data_9IC3
# 
_entry.id   9IC3 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9IC3         pdb_00009ic3 10.2210/pdb9ic3/pdb 
WWPDB D_1292145499 ?            ?                   
EMDB  EMD-52828    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-04 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9IC3 
_pdbx_database_status.recvd_initial_deposition_date   2025-02-14 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'Consensus map'                                                                                                        
EMD-52825 'consensus EM volume'  
EMDB 'Local refinement map of subunit A and DNA'                                                                            
EMD-52826 'focused EM volume'    
EMDB 'Local refinement map of subunit B'                                                                                    
EMD-52827 'focused EM volume'    
PDB  .                                                                                                                      9G74 
unspecified            
PDB  .                                                                                                                      9G75 
unspecified            
PDB  .                                                                                                                      9G77 
unspecified            
EMDB 'Chimeric mitochondrial DNA polymerase gamma ternary complex (hAmB) in mouse-like error-editing conformer (composite)' 
EMD-52828 'associated EM volume' 
PDB  .                                                                                                                      9IBX 
unspecified            
PDB  .                                                                                                                      9IBZ 
unspecified            
PDB  .                                                                                                                      9IC0 
unspecified            
PDB  .                                                                                                                      9IC1 
unspecified            
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              maria.falkenberg@medkem.gu.se 
_pdbx_contact_author.name_first         Maria 
_pdbx_contact_author.name_last          Falkenberg 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-8713-173X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Valenzuela, S.' 1 0000-0001-5153-8431 
'Falkenberg, M.' 2 0000-0001-8713-173X 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                4782 
_citation.page_last                 4782 
_citation.title                     
'Modelling POLG mutations in mice unravels a critical role of POL gamma Beta in regulating phenotypic severity.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-60059-y 
_citation.pdbx_database_id_PubMed   40404629 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Corra, S.'          1  ?                   
primary 'Zuppardo, A.'       2  0000-0001-9601-3567 
primary 'Valenzuela, S.'     3  0000-0001-5153-8431 
primary 'Jenninger, L.'      4  ?                   
primary 'Cerutti, R.'        5  ?                   
primary 'Sillamaa, S.'       6  0000-0001-8077-9963 
primary 'Hoberg, E.'         7  ?                   
primary 'Johansson, K.A.S.'  8  0009-0005-8992-7631 
primary 'Rovsnik, U.'        9  ?                   
primary 'Volta, S.'          10 ?                   
primary 'Silva-Pinheiro, P.' 11 0000-0002-0872-5749 
primary 'Davis, H.'          12 ?                   
primary 'Trifunovic, A.'     13 0000-0002-5472-3517 
primary 'Minczuk, M.'        14 0000-0001-8242-1420 
primary 'Gustafsson, C.M.'   15 0000-0003-3531-8468 
primary 'Suomalainen, A.'    16 0000-0003-4833-5195 
primary 'Zeviani, M.'        17 ?                   
primary 'Macao, B.'          18 0000-0001-6511-6125 
primary 'Zhu, X.'            19 0000-0002-4759-4446 
primary 'Falkenberg, M.'     20 0000-0001-8713-173X 
primary 'Viscomi, C.'        21 0000-0001-6050-0566 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'DNA polymerase subunit gamma-1'   138044.641 1 2.7.7.7,3.1.11.-,4.2.99.- ? ? ? 
2 polymer     man 'DNA polymerase subunit gamma-2'   50778.648  2 ?                         ? ? ? 
3 polymer     syn 'DNA (primer strand)'              7780.008   1 ?                         ? ? ? 
4 polymer     syn 'DNA (template strand)'            12162.783  1 ?                         ? ? ? 
5 non-polymer syn 'CALCIUM ION'                      40.078     3 ?                         ? ? ? 
6 non-polymer syn "2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE" 467.157    1 ?                         ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 
;3'-5' exodeoxyribonuclease,5'-deoxyribose-phosphate lyase,Mitochondrial DNA polymerase catalytic subunit,PolG-alpha
;
2 'DNA polymerase gamma accessory 55 kDa subunit,p55,Mitochondrial DNA polymerase accessory subunit,MtPolB,PolG-beta'   
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'        no no 
;MHHHHHHVSSSVPASDPSDGQRRRQQQQQQQQQQQQQPQQPQVLSSEGGQLRHNPLDIQMLSRGLHEQIFGQGGEMPGEA
AVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRY
GPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQ
RDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARR
GPAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERC
PHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQK
KAKKVKKEPATASKLPIEGAGAPGDPMDQEDLGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCP
RLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPGRRDNLAKLPTGTTLESAGVVCPYRAIESLYRK
HCLEQGKQQLMPQEAGLAEEFLLTDNSAIWQTVEELDYLEVEAEAKMENLRAAVPGQPLALTARGGPKDTQPSYHHGNGP
YNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPR
SALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWI
AAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEA
AEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMF
NKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVR
YLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEAL
DIYQIIELTKGSLEKRSQPGP
;
;MHHHHHHVSSSVPASDPSDGQRRRQQQQQQQQQQQQQPQQPQVLSSEGGQLRHNPLDIQMLSRGLHEQIFGQGGEMPGEA
AVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRY
GPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQ
RDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARR
GPAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERC
PHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQK
KAKKVKKEPATASKLPIEGAGAPGDPMDQEDLGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCP
RLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPGRRDNLAKLPTGTTLESAGVVCPYRAIESLYRK
HCLEQGKQQLMPQEAGLAEEFLLTDNSAIWQTVEELDYLEVEAEAKMENLRAAVPGQPLALTARGGPKDTQPSYHHGNGP
YNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPR
SALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWI
AAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEA
AEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMF
NKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVR
YLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEAL
DIYQIIELTKGSLEKRSQPGP
;
A   ? 
2 'polypeptide(L)'        no no 
;MWLSGYAGPADGTQQPDAPEHAVAREALVDLCRRRHFFSGTPQQLSTAALLSGCHARFGPLGVELRKNLASQWWSSMVVF
REQVFAVDSLHQEPGSSQPRDSAFRLVSPESIREILQDREPSKEQLVAFLENLLKTSGKLRATLLHGALEHYVNCLDLVN
RKLPFGLAQIGVCFHPVSNSNQTPSSVTRVGEKTEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAMSPSNFSSADCQDE
LGRKGSKLYYSFPWGKEPIETLWNLGDQELLHTYPGNVSTIQGRDGRKNVVPCVLSVSGDVDLGTLAYLYDSFQLAENSF
ARKKSLQRKVLKLHPCLAPIKVALDVGKGPTVELRQVCQGLLNELLENGISVWPGYSETVHSSLEQLHSKYDEMSVLFSV
LVTETTLENGLIQLRSRDTTMKEMMHISKLRDFLVKYLASASNVHHHHHH
;
;MWLSGYAGPADGTQQPDAPEHAVAREALVDLCRRRHFFSGTPQQLSTAALLSGCHARFGPLGVELRKNLASQWWSSMVVF
REQVFAVDSLHQEPGSSQPRDSAFRLVSPESIREILQDREPSKEQLVAFLENLLKTSGKLRATLLHGALEHYVNCLDLVN
RKLPFGLAQIGVCFHPVSNSNQTPSSVTRVGEKTEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAMSPSNFSSADCQDE
LGRKGSKLYYSFPWGKEPIETLWNLGDQELLHTYPGNVSTIQGRDGRKNVVPCVLSVSGDVDLGTLAYLYDSFQLAENSF
ARKKSLQRKVLKLHPCLAPIKVALDVGKGPTVELRQVCQGLLNELLENGISVWPGYSETVHSSLEQLHSKYDEMSVLFSV
LVTETTLENGLIQLRSRDTTMKEMMHISKLRDFLVKYLASASNVHHHHHH
;
B,C ? 
3 polydeoxyribonucleotide no no 
;(DG)(DC)(DA)(DT)(DG)(DC)(DG)(DG)(DT)(DC)(DG)(DA)(DG)(DT)(DC)(DT)(DA)(DG)(DA)(DG)
(DG)(DA)(DG)(DC)(DT)
;
GCATGCGGTCGAGTCTAGAGGAGCT P   ? 
4 polydeoxyribonucleotide no no 
;(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DA)(DT)(DC)(DC)(DG)(DG)(DG)(DC)(DT)(DC)
(DC)(DT)(DC)(DT)(DA)(DG)(DA)(DC)(DT)(DC)(DG)(DA)(DC)(DC)(DG)(DC)(DA)(DT)(DG)(DC)
;
TTTTTTTTTTATCCGGGCTCCTCTAGACTCGACCGCATGC T   ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
5 'CALCIUM ION'                      CA  
6 "2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE" DCP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1    MET n 
1 2    HIS n 
1 3    HIS n 
1 4    HIS n 
1 5    HIS n 
1 6    HIS n 
1 7    HIS n 
1 8    VAL n 
1 9    SER n 
1 10   SER n 
1 11   SER n 
1 12   VAL n 
1 13   PRO n 
1 14   ALA n 
1 15   SER n 
1 16   ASP n 
1 17   PRO n 
1 18   SER n 
1 19   ASP n 
1 20   GLY n 
1 21   GLN n 
1 22   ARG n 
1 23   ARG n 
1 24   ARG n 
1 25   GLN n 
1 26   GLN n 
1 27   GLN n 
1 28   GLN n 
1 29   GLN n 
1 30   GLN n 
1 31   GLN n 
1 32   GLN n 
1 33   GLN n 
1 34   GLN n 
1 35   GLN n 
1 36   GLN n 
1 37   GLN n 
1 38   PRO n 
1 39   GLN n 
1 40   GLN n 
1 41   PRO n 
1 42   GLN n 
1 43   VAL n 
1 44   LEU n 
1 45   SER n 
1 46   SER n 
1 47   GLU n 
1 48   GLY n 
1 49   GLY n 
1 50   GLN n 
1 51   LEU n 
1 52   ARG n 
1 53   HIS n 
1 54   ASN n 
1 55   PRO n 
1 56   LEU n 
1 57   ASP n 
1 58   ILE n 
1 59   GLN n 
1 60   MET n 
1 61   LEU n 
1 62   SER n 
1 63   ARG n 
1 64   GLY n 
1 65   LEU n 
1 66   HIS n 
1 67   GLU n 
1 68   GLN n 
1 69   ILE n 
1 70   PHE n 
1 71   GLY n 
1 72   GLN n 
1 73   GLY n 
1 74   GLY n 
1 75   GLU n 
1 76   MET n 
1 77   PRO n 
1 78   GLY n 
1 79   GLU n 
1 80   ALA n 
1 81   ALA n 
1 82   VAL n 
1 83   ARG n 
1 84   ARG n 
1 85   SER n 
1 86   VAL n 
1 87   GLU n 
1 88   HIS n 
1 89   LEU n 
1 90   GLN n 
1 91   LYS n 
1 92   HIS n 
1 93   GLY n 
1 94   LEU n 
1 95   TRP n 
1 96   GLY n 
1 97   GLN n 
1 98   PRO n 
1 99   ALA n 
1 100  VAL n 
1 101  PRO n 
1 102  LEU n 
1 103  PRO n 
1 104  ASP n 
1 105  VAL n 
1 106  GLU n 
1 107  LEU n 
1 108  ARG n 
1 109  LEU n 
1 110  PRO n 
1 111  PRO n 
1 112  LEU n 
1 113  TYR n 
1 114  GLY n 
1 115  ASP n 
1 116  ASN n 
1 117  LEU n 
1 118  ASP n 
1 119  GLN n 
1 120  HIS n 
1 121  PHE n 
1 122  ARG n 
1 123  LEU n 
1 124  LEU n 
1 125  ALA n 
1 126  GLN n 
1 127  LYS n 
1 128  GLN n 
1 129  SER n 
1 130  LEU n 
1 131  PRO n 
1 132  TYR n 
1 133  LEU n 
1 134  GLU n 
1 135  ALA n 
1 136  ALA n 
1 137  ASN n 
1 138  LEU n 
1 139  LEU n 
1 140  LEU n 
1 141  GLN n 
1 142  ALA n 
1 143  GLN n 
1 144  LEU n 
1 145  PRO n 
1 146  PRO n 
1 147  LYS n 
1 148  PRO n 
1 149  PRO n 
1 150  ALA n 
1 151  TRP n 
1 152  ALA n 
1 153  TRP n 
1 154  ALA n 
1 155  GLU n 
1 156  GLY n 
1 157  TRP n 
1 158  THR n 
1 159  ARG n 
1 160  TYR n 
1 161  GLY n 
1 162  PRO n 
1 163  GLU n 
1 164  GLY n 
1 165  GLU n 
1 166  ALA n 
1 167  VAL n 
1 168  PRO n 
1 169  VAL n 
1 170  ALA n 
1 171  ILE n 
1 172  PRO n 
1 173  GLU n 
1 174  GLU n 
1 175  ARG n 
1 176  ALA n 
1 177  LEU n 
1 178  VAL n 
1 179  PHE n 
1 180  ASP n 
1 181  VAL n 
1 182  GLU n 
1 183  VAL n 
1 184  CYS n 
1 185  LEU n 
1 186  ALA n 
1 187  GLU n 
1 188  GLY n 
1 189  THR n 
1 190  CYS n 
1 191  PRO n 
1 192  THR n 
1 193  LEU n 
1 194  ALA n 
1 195  VAL n 
1 196  ALA n 
1 197  ILE n 
1 198  SER n 
1 199  PRO n 
1 200  SER n 
1 201  ALA n 
1 202  TRP n 
1 203  TYR n 
1 204  SER n 
1 205  TRP n 
1 206  CYS n 
1 207  SER n 
1 208  GLN n 
1 209  ARG n 
1 210  LEU n 
1 211  VAL n 
1 212  GLU n 
1 213  GLU n 
1 214  ARG n 
1 215  TYR n 
1 216  SER n 
1 217  TRP n 
1 218  THR n 
1 219  SER n 
1 220  GLN n 
1 221  LEU n 
1 222  SER n 
1 223  PRO n 
1 224  ALA n 
1 225  ASP n 
1 226  LEU n 
1 227  ILE n 
1 228  PRO n 
1 229  LEU n 
1 230  GLU n 
1 231  VAL n 
1 232  PRO n 
1 233  THR n 
1 234  GLY n 
1 235  ALA n 
1 236  SER n 
1 237  SER n 
1 238  PRO n 
1 239  THR n 
1 240  GLN n 
1 241  ARG n 
1 242  ASP n 
1 243  TRP n 
1 244  GLN n 
1 245  GLU n 
1 246  GLN n 
1 247  LEU n 
1 248  VAL n 
1 249  VAL n 
1 250  GLY n 
1 251  HIS n 
1 252  ASN n 
1 253  VAL n 
1 254  SER n 
1 255  PHE n 
1 256  ASP n 
1 257  ARG n 
1 258  ALA n 
1 259  HIS n 
1 260  ILE n 
1 261  ARG n 
1 262  GLU n 
1 263  GLN n 
1 264  TYR n 
1 265  LEU n 
1 266  ILE n 
1 267  GLN n 
1 268  GLY n 
1 269  SER n 
1 270  ARG n 
1 271  MET n 
1 272  ARG n 
1 273  PHE n 
1 274  LEU n 
1 275  ASP n 
1 276  THR n 
1 277  MET n 
1 278  SER n 
1 279  MET n 
1 280  HIS n 
1 281  MET n 
1 282  ALA n 
1 283  ILE n 
1 284  SER n 
1 285  GLY n 
1 286  LEU n 
1 287  SER n 
1 288  SER n 
1 289  PHE n 
1 290  GLN n 
1 291  ARG n 
1 292  SER n 
1 293  LEU n 
1 294  TRP n 
1 295  ILE n 
1 296  ALA n 
1 297  ALA n 
1 298  LYS n 
1 299  GLN n 
1 300  GLY n 
1 301  LYS n 
1 302  HIS n 
1 303  LYS n 
1 304  VAL n 
1 305  GLN n 
1 306  PRO n 
1 307  PRO n 
1 308  THR n 
1 309  LYS n 
1 310  GLN n 
1 311  GLY n 
1 312  GLN n 
1 313  LYS n 
1 314  SER n 
1 315  GLN n 
1 316  ARG n 
1 317  LYS n 
1 318  ALA n 
1 319  ARG n 
1 320  ARG n 
1 321  GLY n 
1 322  PRO n 
1 323  ALA n 
1 324  ILE n 
1 325  SER n 
1 326  SER n 
1 327  TRP n 
1 328  ASP n 
1 329  TRP n 
1 330  LEU n 
1 331  ASP n 
1 332  ILE n 
1 333  SER n 
1 334  SER n 
1 335  VAL n 
1 336  ASN n 
1 337  SER n 
1 338  LEU n 
1 339  ALA n 
1 340  GLU n 
1 341  VAL n 
1 342  HIS n 
1 343  ARG n 
1 344  LEU n 
1 345  TYR n 
1 346  VAL n 
1 347  GLY n 
1 348  GLY n 
1 349  PRO n 
1 350  PRO n 
1 351  LEU n 
1 352  GLU n 
1 353  LYS n 
1 354  GLU n 
1 355  PRO n 
1 356  ARG n 
1 357  GLU n 
1 358  LEU n 
1 359  PHE n 
1 360  VAL n 
1 361  LYS n 
1 362  GLY n 
1 363  THR n 
1 364  MET n 
1 365  LYS n 
1 366  ASP n 
1 367  ILE n 
1 368  ARG n 
1 369  GLU n 
1 370  ASN n 
1 371  PHE n 
1 372  GLN n 
1 373  ASP n 
1 374  LEU n 
1 375  MET n 
1 376  GLN n 
1 377  TYR n 
1 378  CYS n 
1 379  ALA n 
1 380  GLN n 
1 381  ASP n 
1 382  VAL n 
1 383  TRP n 
1 384  ALA n 
1 385  THR n 
1 386  HIS n 
1 387  GLU n 
1 388  VAL n 
1 389  PHE n 
1 390  GLN n 
1 391  GLN n 
1 392  GLN n 
1 393  LEU n 
1 394  PRO n 
1 395  LEU n 
1 396  PHE n 
1 397  LEU n 
1 398  GLU n 
1 399  ARG n 
1 400  CYS n 
1 401  PRO n 
1 402  HIS n 
1 403  PRO n 
1 404  VAL n 
1 405  THR n 
1 406  LEU n 
1 407  ALA n 
1 408  GLY n 
1 409  MET n 
1 410  LEU n 
1 411  GLU n 
1 412  MET n 
1 413  GLY n 
1 414  VAL n 
1 415  SER n 
1 416  TYR n 
1 417  LEU n 
1 418  PRO n 
1 419  VAL n 
1 420  ASN n 
1 421  GLN n 
1 422  ASN n 
1 423  TRP n 
1 424  GLU n 
1 425  ARG n 
1 426  TYR n 
1 427  LEU n 
1 428  ALA n 
1 429  GLU n 
1 430  ALA n 
1 431  GLN n 
1 432  GLY n 
1 433  THR n 
1 434  TYR n 
1 435  GLU n 
1 436  GLU n 
1 437  LEU n 
1 438  GLN n 
1 439  ARG n 
1 440  GLU n 
1 441  MET n 
1 442  LYS n 
1 443  LYS n 
1 444  SER n 
1 445  LEU n 
1 446  MET n 
1 447  ASP n 
1 448  LEU n 
1 449  ALA n 
1 450  ASN n 
1 451  ASP n 
1 452  ALA n 
1 453  CYS n 
1 454  GLN n 
1 455  LEU n 
1 456  LEU n 
1 457  SER n 
1 458  GLY n 
1 459  GLU n 
1 460  ARG n 
1 461  TYR n 
1 462  LYS n 
1 463  GLU n 
1 464  ASP n 
1 465  PRO n 
1 466  TRP n 
1 467  LEU n 
1 468  TRP n 
1 469  ASP n 
1 470  LEU n 
1 471  GLU n 
1 472  TRP n 
1 473  ASP n 
1 474  LEU n 
1 475  GLN n 
1 476  GLU n 
1 477  PHE n 
1 478  LYS n 
1 479  GLN n 
1 480  LYS n 
1 481  LYS n 
1 482  ALA n 
1 483  LYS n 
1 484  LYS n 
1 485  VAL n 
1 486  LYS n 
1 487  LYS n 
1 488  GLU n 
1 489  PRO n 
1 490  ALA n 
1 491  THR n 
1 492  ALA n 
1 493  SER n 
1 494  LYS n 
1 495  LEU n 
1 496  PRO n 
1 497  ILE n 
1 498  GLU n 
1 499  GLY n 
1 500  ALA n 
1 501  GLY n 
1 502  ALA n 
1 503  PRO n 
1 504  GLY n 
1 505  ASP n 
1 506  PRO n 
1 507  MET n 
1 508  ASP n 
1 509  GLN n 
1 510  GLU n 
1 511  ASP n 
1 512  LEU n 
1 513  GLY n 
1 514  PRO n 
1 515  CYS n 
1 516  SER n 
1 517  GLU n 
1 518  GLU n 
1 519  GLU n 
1 520  GLU n 
1 521  PHE n 
1 522  GLN n 
1 523  GLN n 
1 524  ASP n 
1 525  VAL n 
1 526  MET n 
1 527  ALA n 
1 528  ARG n 
1 529  ALA n 
1 530  CYS n 
1 531  LEU n 
1 532  GLN n 
1 533  LYS n 
1 534  LEU n 
1 535  LYS n 
1 536  GLY n 
1 537  THR n 
1 538  THR n 
1 539  GLU n 
1 540  LEU n 
1 541  LEU n 
1 542  PRO n 
1 543  LYS n 
1 544  ARG n 
1 545  PRO n 
1 546  GLN n 
1 547  HIS n 
1 548  LEU n 
1 549  PRO n 
1 550  GLY n 
1 551  HIS n 
1 552  PRO n 
1 553  GLY n 
1 554  TRP n 
1 555  TYR n 
1 556  ARG n 
1 557  LYS n 
1 558  LEU n 
1 559  CYS n 
1 560  PRO n 
1 561  ARG n 
1 562  LEU n 
1 563  ASP n 
1 564  ASP n 
1 565  PRO n 
1 566  ALA n 
1 567  TRP n 
1 568  THR n 
1 569  PRO n 
1 570  GLY n 
1 571  PRO n 
1 572  SER n 
1 573  LEU n 
1 574  LEU n 
1 575  SER n 
1 576  LEU n 
1 577  GLN n 
1 578  MET n 
1 579  ARG n 
1 580  VAL n 
1 581  THR n 
1 582  PRO n 
1 583  LYS n 
1 584  LEU n 
1 585  MET n 
1 586  ALA n 
1 587  LEU n 
1 588  THR n 
1 589  TRP n 
1 590  ASP n 
1 591  GLY n 
1 592  PHE n 
1 593  PRO n 
1 594  LEU n 
1 595  HIS n 
1 596  TYR n 
1 597  SER n 
1 598  GLU n 
1 599  ARG n 
1 600  HIS n 
1 601  GLY n 
1 602  TRP n 
1 603  GLY n 
1 604  TYR n 
1 605  LEU n 
1 606  VAL n 
1 607  PRO n 
1 608  GLY n 
1 609  ARG n 
1 610  ARG n 
1 611  ASP n 
1 612  ASN n 
1 613  LEU n 
1 614  ALA n 
1 615  LYS n 
1 616  LEU n 
1 617  PRO n 
1 618  THR n 
1 619  GLY n 
1 620  THR n 
1 621  THR n 
1 622  LEU n 
1 623  GLU n 
1 624  SER n 
1 625  ALA n 
1 626  GLY n 
1 627  VAL n 
1 628  VAL n 
1 629  CYS n 
1 630  PRO n 
1 631  TYR n 
1 632  ARG n 
1 633  ALA n 
1 634  ILE n 
1 635  GLU n 
1 636  SER n 
1 637  LEU n 
1 638  TYR n 
1 639  ARG n 
1 640  LYS n 
1 641  HIS n 
1 642  CYS n 
1 643  LEU n 
1 644  GLU n 
1 645  GLN n 
1 646  GLY n 
1 647  LYS n 
1 648  GLN n 
1 649  GLN n 
1 650  LEU n 
1 651  MET n 
1 652  PRO n 
1 653  GLN n 
1 654  GLU n 
1 655  ALA n 
1 656  GLY n 
1 657  LEU n 
1 658  ALA n 
1 659  GLU n 
1 660  GLU n 
1 661  PHE n 
1 662  LEU n 
1 663  LEU n 
1 664  THR n 
1 665  ASP n 
1 666  ASN n 
1 667  SER n 
1 668  ALA n 
1 669  ILE n 
1 670  TRP n 
1 671  GLN n 
1 672  THR n 
1 673  VAL n 
1 674  GLU n 
1 675  GLU n 
1 676  LEU n 
1 677  ASP n 
1 678  TYR n 
1 679  LEU n 
1 680  GLU n 
1 681  VAL n 
1 682  GLU n 
1 683  ALA n 
1 684  GLU n 
1 685  ALA n 
1 686  LYS n 
1 687  MET n 
1 688  GLU n 
1 689  ASN n 
1 690  LEU n 
1 691  ARG n 
1 692  ALA n 
1 693  ALA n 
1 694  VAL n 
1 695  PRO n 
1 696  GLY n 
1 697  GLN n 
1 698  PRO n 
1 699  LEU n 
1 700  ALA n 
1 701  LEU n 
1 702  THR n 
1 703  ALA n 
1 704  ARG n 
1 705  GLY n 
1 706  GLY n 
1 707  PRO n 
1 708  LYS n 
1 709  ASP n 
1 710  THR n 
1 711  GLN n 
1 712  PRO n 
1 713  SER n 
1 714  TYR n 
1 715  HIS n 
1 716  HIS n 
1 717  GLY n 
1 718  ASN n 
1 719  GLY n 
1 720  PRO n 
1 721  TYR n 
1 722  ASN n 
1 723  ASP n 
1 724  VAL n 
1 725  ASP n 
1 726  ILE n 
1 727  PRO n 
1 728  GLY n 
1 729  CYS n 
1 730  TRP n 
1 731  PHE n 
1 732  PHE n 
1 733  LYS n 
1 734  LEU n 
1 735  PRO n 
1 736  HIS n 
1 737  LYS n 
1 738  ASP n 
1 739  GLY n 
1 740  ASN n 
1 741  SER n 
1 742  CYS n 
1 743  ASN n 
1 744  VAL n 
1 745  GLY n 
1 746  SER n 
1 747  PRO n 
1 748  PHE n 
1 749  ALA n 
1 750  LYS n 
1 751  ASP n 
1 752  PHE n 
1 753  LEU n 
1 754  PRO n 
1 755  LYS n 
1 756  MET n 
1 757  GLU n 
1 758  ASP n 
1 759  GLY n 
1 760  THR n 
1 761  LEU n 
1 762  GLN n 
1 763  ALA n 
1 764  GLY n 
1 765  PRO n 
1 766  GLY n 
1 767  GLY n 
1 768  ALA n 
1 769  SER n 
1 770  GLY n 
1 771  PRO n 
1 772  ARG n 
1 773  ALA n 
1 774  LEU n 
1 775  GLU n 
1 776  ILE n 
1 777  ASN n 
1 778  LYS n 
1 779  MET n 
1 780  ILE n 
1 781  SER n 
1 782  PHE n 
1 783  TRP n 
1 784  ARG n 
1 785  ASN n 
1 786  ALA n 
1 787  HIS n 
1 788  LYS n 
1 789  ARG n 
1 790  ILE n 
1 791  SER n 
1 792  SER n 
1 793  GLN n 
1 794  MET n 
1 795  VAL n 
1 796  VAL n 
1 797  TRP n 
1 798  LEU n 
1 799  PRO n 
1 800  ARG n 
1 801  SER n 
1 802  ALA n 
1 803  LEU n 
1 804  PRO n 
1 805  ARG n 
1 806  ALA n 
1 807  VAL n 
1 808  ILE n 
1 809  ARG n 
1 810  HIS n 
1 811  PRO n 
1 812  ASP n 
1 813  TYR n 
1 814  ASP n 
1 815  GLU n 
1 816  GLU n 
1 817  GLY n 
1 818  LEU n 
1 819  TYR n 
1 820  GLY n 
1 821  ALA n 
1 822  ILE n 
1 823  LEU n 
1 824  PRO n 
1 825  GLN n 
1 826  VAL n 
1 827  VAL n 
1 828  THR n 
1 829  ALA n 
1 830  GLY n 
1 831  THR n 
1 832  ILE n 
1 833  THR n 
1 834  ARG n 
1 835  ARG n 
1 836  ALA n 
1 837  VAL n 
1 838  GLU n 
1 839  PRO n 
1 840  THR n 
1 841  TRP n 
1 842  LEU n 
1 843  THR n 
1 844  ALA n 
1 845  SER n 
1 846  ASN n 
1 847  ALA n 
1 848  ARG n 
1 849  PRO n 
1 850  ASP n 
1 851  ARG n 
1 852  VAL n 
1 853  GLY n 
1 854  SER n 
1 855  GLU n 
1 856  LEU n 
1 857  LYS n 
1 858  ALA n 
1 859  MET n 
1 860  VAL n 
1 861  GLN n 
1 862  ALA n 
1 863  PRO n 
1 864  PRO n 
1 865  GLY n 
1 866  TYR n 
1 867  THR n 
1 868  LEU n 
1 869  VAL n 
1 870  GLY n 
1 871  ALA n 
1 872  ASP n 
1 873  VAL n 
1 874  ASP n 
1 875  SER n 
1 876  GLN n 
1 877  GLU n 
1 878  LEU n 
1 879  TRP n 
1 880  ILE n 
1 881  ALA n 
1 882  ALA n 
1 883  VAL n 
1 884  LEU n 
1 885  GLY n 
1 886  ASP n 
1 887  ALA n 
1 888  HIS n 
1 889  PHE n 
1 890  ALA n 
1 891  GLY n 
1 892  MET n 
1 893  HIS n 
1 894  GLY n 
1 895  CYS n 
1 896  THR n 
1 897  ALA n 
1 898  PHE n 
1 899  GLY n 
1 900  TRP n 
1 901  MET n 
1 902  THR n 
1 903  LEU n 
1 904  GLN n 
1 905  GLY n 
1 906  ARG n 
1 907  LYS n 
1 908  SER n 
1 909  ARG n 
1 910  GLY n 
1 911  THR n 
1 912  ASP n 
1 913  LEU n 
1 914  HIS n 
1 915  SER n 
1 916  LYS n 
1 917  THR n 
1 918  ALA n 
1 919  THR n 
1 920  THR n 
1 921  VAL n 
1 922  GLY n 
1 923  ILE n 
1 924  SER n 
1 925  ARG n 
1 926  GLU n 
1 927  HIS n 
1 928  ALA n 
1 929  LYS n 
1 930  ILE n 
1 931  PHE n 
1 932  ASN n 
1 933  TYR n 
1 934  GLY n 
1 935  ARG n 
1 936  ILE n 
1 937  TYR n 
1 938  GLY n 
1 939  ALA n 
1 940  GLY n 
1 941  GLN n 
1 942  PRO n 
1 943  PHE n 
1 944  ALA n 
1 945  GLU n 
1 946  ARG n 
1 947  LEU n 
1 948  LEU n 
1 949  MET n 
1 950  GLN n 
1 951  PHE n 
1 952  ASN n 
1 953  HIS n 
1 954  ARG n 
1 955  LEU n 
1 956  THR n 
1 957  GLN n 
1 958  GLN n 
1 959  GLU n 
1 960  ALA n 
1 961  ALA n 
1 962  GLU n 
1 963  LYS n 
1 964  ALA n 
1 965  GLN n 
1 966  GLN n 
1 967  MET n 
1 968  TYR n 
1 969  ALA n 
1 970  ALA n 
1 971  THR n 
1 972  LYS n 
1 973  GLY n 
1 974  LEU n 
1 975  ARG n 
1 976  TRP n 
1 977  TYR n 
1 978  ARG n 
1 979  LEU n 
1 980  SER n 
1 981  ASP n 
1 982  GLU n 
1 983  GLY n 
1 984  GLU n 
1 985  TRP n 
1 986  LEU n 
1 987  VAL n 
1 988  ARG n 
1 989  GLU n 
1 990  LEU n 
1 991  ASN n 
1 992  LEU n 
1 993  PRO n 
1 994  VAL n 
1 995  ASP n 
1 996  ARG n 
1 997  THR n 
1 998  GLU n 
1 999  GLY n 
1 1000 GLY n 
1 1001 TRP n 
1 1002 ILE n 
1 1003 SER n 
1 1004 LEU n 
1 1005 GLN n 
1 1006 ASP n 
1 1007 LEU n 
1 1008 ARG n 
1 1009 LYS n 
1 1010 VAL n 
1 1011 GLN n 
1 1012 ARG n 
1 1013 GLU n 
1 1014 THR n 
1 1015 ALA n 
1 1016 ARG n 
1 1017 LYS n 
1 1018 SER n 
1 1019 GLN n 
1 1020 TRP n 
1 1021 LYS n 
1 1022 LYS n 
1 1023 TRP n 
1 1024 GLU n 
1 1025 VAL n 
1 1026 VAL n 
1 1027 ALA n 
1 1028 GLU n 
1 1029 ARG n 
1 1030 ALA n 
1 1031 TRP n 
1 1032 LYS n 
1 1033 GLY n 
1 1034 GLY n 
1 1035 THR n 
1 1036 GLU n 
1 1037 SER n 
1 1038 GLU n 
1 1039 MET n 
1 1040 PHE n 
1 1041 ASN n 
1 1042 LYS n 
1 1043 LEU n 
1 1044 GLU n 
1 1045 SER n 
1 1046 ILE n 
1 1047 ALA n 
1 1048 THR n 
1 1049 SER n 
1 1050 ASP n 
1 1051 ILE n 
1 1052 PRO n 
1 1053 ARG n 
1 1054 THR n 
1 1055 PRO n 
1 1056 VAL n 
1 1057 LEU n 
1 1058 GLY n 
1 1059 CYS n 
1 1060 CYS n 
1 1061 ILE n 
1 1062 SER n 
1 1063 ARG n 
1 1064 ALA n 
1 1065 LEU n 
1 1066 GLU n 
1 1067 PRO n 
1 1068 SER n 
1 1069 ALA n 
1 1070 VAL n 
1 1071 GLN n 
1 1072 GLU n 
1 1073 GLU n 
1 1074 PHE n 
1 1075 MET n 
1 1076 THR n 
1 1077 SER n 
1 1078 ARG n 
1 1079 VAL n 
1 1080 ASN n 
1 1081 TRP n 
1 1082 VAL n 
1 1083 VAL n 
1 1084 GLN n 
1 1085 SER n 
1 1086 SER n 
1 1087 ALA n 
1 1088 VAL n 
1 1089 ASP n 
1 1090 TYR n 
1 1091 LEU n 
1 1092 HIS n 
1 1093 LEU n 
1 1094 MET n 
1 1095 LEU n 
1 1096 VAL n 
1 1097 ALA n 
1 1098 MET n 
1 1099 LYS n 
1 1100 TRP n 
1 1101 LEU n 
1 1102 PHE n 
1 1103 GLU n 
1 1104 GLU n 
1 1105 PHE n 
1 1106 ALA n 
1 1107 ILE n 
1 1108 ASP n 
1 1109 GLY n 
1 1110 ARG n 
1 1111 PHE n 
1 1112 CYS n 
1 1113 ILE n 
1 1114 SER n 
1 1115 ILE n 
1 1116 HIS n 
1 1117 ASP n 
1 1118 GLU n 
1 1119 VAL n 
1 1120 ARG n 
1 1121 TYR n 
1 1122 LEU n 
1 1123 VAL n 
1 1124 ARG n 
1 1125 GLU n 
1 1126 GLU n 
1 1127 ASP n 
1 1128 ARG n 
1 1129 TYR n 
1 1130 ARG n 
1 1131 ALA n 
1 1132 ALA n 
1 1133 LEU n 
1 1134 ALA n 
1 1135 LEU n 
1 1136 GLN n 
1 1137 ILE n 
1 1138 THR n 
1 1139 ASN n 
1 1140 LEU n 
1 1141 LEU n 
1 1142 THR n 
1 1143 ARG n 
1 1144 CYS n 
1 1145 MET n 
1 1146 PHE n 
1 1147 ALA n 
1 1148 TYR n 
1 1149 LYS n 
1 1150 LEU n 
1 1151 GLY n 
1 1152 LEU n 
1 1153 ASN n 
1 1154 ASP n 
1 1155 LEU n 
1 1156 PRO n 
1 1157 GLN n 
1 1158 SER n 
1 1159 VAL n 
1 1160 ALA n 
1 1161 PHE n 
1 1162 PHE n 
1 1163 SER n 
1 1164 ALA n 
1 1165 VAL n 
1 1166 ASP n 
1 1167 ILE n 
1 1168 ASP n 
1 1169 ARG n 
1 1170 CYS n 
1 1171 LEU n 
1 1172 ARG n 
1 1173 LYS n 
1 1174 GLU n 
1 1175 VAL n 
1 1176 THR n 
1 1177 MET n 
1 1178 ASP n 
1 1179 CYS n 
1 1180 LYS n 
1 1181 THR n 
1 1182 PRO n 
1 1183 SER n 
1 1184 ASN n 
1 1185 PRO n 
1 1186 THR n 
1 1187 GLY n 
1 1188 MET n 
1 1189 GLU n 
1 1190 ARG n 
1 1191 ARG n 
1 1192 TYR n 
1 1193 GLY n 
1 1194 ILE n 
1 1195 PRO n 
1 1196 GLN n 
1 1197 GLY n 
1 1198 GLU n 
1 1199 ALA n 
1 1200 LEU n 
1 1201 ASP n 
1 1202 ILE n 
1 1203 TYR n 
1 1204 GLN n 
1 1205 ILE n 
1 1206 ILE n 
1 1207 GLU n 
1 1208 LEU n 
1 1209 THR n 
1 1210 LYS n 
1 1211 GLY n 
1 1212 SER n 
1 1213 LEU n 
1 1214 GLU n 
1 1215 LYS n 
1 1216 ARG n 
1 1217 SER n 
1 1218 GLN n 
1 1219 PRO n 
1 1220 GLY n 
1 1221 PRO n 
2 1    MET n 
2 2    TRP n 
2 3    LEU n 
2 4    SER n 
2 5    GLY n 
2 6    TYR n 
2 7    ALA n 
2 8    GLY n 
2 9    PRO n 
2 10   ALA n 
2 11   ASP n 
2 12   GLY n 
2 13   THR n 
2 14   GLN n 
2 15   GLN n 
2 16   PRO n 
2 17   ASP n 
2 18   ALA n 
2 19   PRO n 
2 20   GLU n 
2 21   HIS n 
2 22   ALA n 
2 23   VAL n 
2 24   ALA n 
2 25   ARG n 
2 26   GLU n 
2 27   ALA n 
2 28   LEU n 
2 29   VAL n 
2 30   ASP n 
2 31   LEU n 
2 32   CYS n 
2 33   ARG n 
2 34   ARG n 
2 35   ARG n 
2 36   HIS n 
2 37   PHE n 
2 38   PHE n 
2 39   SER n 
2 40   GLY n 
2 41   THR n 
2 42   PRO n 
2 43   GLN n 
2 44   GLN n 
2 45   LEU n 
2 46   SER n 
2 47   THR n 
2 48   ALA n 
2 49   ALA n 
2 50   LEU n 
2 51   LEU n 
2 52   SER n 
2 53   GLY n 
2 54   CYS n 
2 55   HIS n 
2 56   ALA n 
2 57   ARG n 
2 58   PHE n 
2 59   GLY n 
2 60   PRO n 
2 61   LEU n 
2 62   GLY n 
2 63   VAL n 
2 64   GLU n 
2 65   LEU n 
2 66   ARG n 
2 67   LYS n 
2 68   ASN n 
2 69   LEU n 
2 70   ALA n 
2 71   SER n 
2 72   GLN n 
2 73   TRP n 
2 74   TRP n 
2 75   SER n 
2 76   SER n 
2 77   MET n 
2 78   VAL n 
2 79   VAL n 
2 80   PHE n 
2 81   ARG n 
2 82   GLU n 
2 83   GLN n 
2 84   VAL n 
2 85   PHE n 
2 86   ALA n 
2 87   VAL n 
2 88   ASP n 
2 89   SER n 
2 90   LEU n 
2 91   HIS n 
2 92   GLN n 
2 93   GLU n 
2 94   PRO n 
2 95   GLY n 
2 96   SER n 
2 97   SER n 
2 98   GLN n 
2 99   PRO n 
2 100  ARG n 
2 101  ASP n 
2 102  SER n 
2 103  ALA n 
2 104  PHE n 
2 105  ARG n 
2 106  LEU n 
2 107  VAL n 
2 108  SER n 
2 109  PRO n 
2 110  GLU n 
2 111  SER n 
2 112  ILE n 
2 113  ARG n 
2 114  GLU n 
2 115  ILE n 
2 116  LEU n 
2 117  GLN n 
2 118  ASP n 
2 119  ARG n 
2 120  GLU n 
2 121  PRO n 
2 122  SER n 
2 123  LYS n 
2 124  GLU n 
2 125  GLN n 
2 126  LEU n 
2 127  VAL n 
2 128  ALA n 
2 129  PHE n 
2 130  LEU n 
2 131  GLU n 
2 132  ASN n 
2 133  LEU n 
2 134  LEU n 
2 135  LYS n 
2 136  THR n 
2 137  SER n 
2 138  GLY n 
2 139  LYS n 
2 140  LEU n 
2 141  ARG n 
2 142  ALA n 
2 143  THR n 
2 144  LEU n 
2 145  LEU n 
2 146  HIS n 
2 147  GLY n 
2 148  ALA n 
2 149  LEU n 
2 150  GLU n 
2 151  HIS n 
2 152  TYR n 
2 153  VAL n 
2 154  ASN n 
2 155  CYS n 
2 156  LEU n 
2 157  ASP n 
2 158  LEU n 
2 159  VAL n 
2 160  ASN n 
2 161  ARG n 
2 162  LYS n 
2 163  LEU n 
2 164  PRO n 
2 165  PHE n 
2 166  GLY n 
2 167  LEU n 
2 168  ALA n 
2 169  GLN n 
2 170  ILE n 
2 171  GLY n 
2 172  VAL n 
2 173  CYS n 
2 174  PHE n 
2 175  HIS n 
2 176  PRO n 
2 177  VAL n 
2 178  SER n 
2 179  ASN n 
2 180  SER n 
2 181  ASN n 
2 182  GLN n 
2 183  THR n 
2 184  PRO n 
2 185  SER n 
2 186  SER n 
2 187  VAL n 
2 188  THR n 
2 189  ARG n 
2 190  VAL n 
2 191  GLY n 
2 192  GLU n 
2 193  LYS n 
2 194  THR n 
2 195  GLU n 
2 196  ALA n 
2 197  SER n 
2 198  LEU n 
2 199  VAL n 
2 200  TRP n 
2 201  PHE n 
2 202  THR n 
2 203  PRO n 
2 204  THR n 
2 205  ARG n 
2 206  THR n 
2 207  SER n 
2 208  SER n 
2 209  GLN n 
2 210  TRP n 
2 211  LEU n 
2 212  ASP n 
2 213  PHE n 
2 214  TRP n 
2 215  LEU n 
2 216  ARG n 
2 217  HIS n 
2 218  ARG n 
2 219  LEU n 
2 220  LEU n 
2 221  TRP n 
2 222  TRP n 
2 223  ARG n 
2 224  LYS n 
2 225  PHE n 
2 226  ALA n 
2 227  MET n 
2 228  SER n 
2 229  PRO n 
2 230  SER n 
2 231  ASN n 
2 232  PHE n 
2 233  SER n 
2 234  SER n 
2 235  ALA n 
2 236  ASP n 
2 237  CYS n 
2 238  GLN n 
2 239  ASP n 
2 240  GLU n 
2 241  LEU n 
2 242  GLY n 
2 243  ARG n 
2 244  LYS n 
2 245  GLY n 
2 246  SER n 
2 247  LYS n 
2 248  LEU n 
2 249  TYR n 
2 250  TYR n 
2 251  SER n 
2 252  PHE n 
2 253  PRO n 
2 254  TRP n 
2 255  GLY n 
2 256  LYS n 
2 257  GLU n 
2 258  PRO n 
2 259  ILE n 
2 260  GLU n 
2 261  THR n 
2 262  LEU n 
2 263  TRP n 
2 264  ASN n 
2 265  LEU n 
2 266  GLY n 
2 267  ASP n 
2 268  GLN n 
2 269  GLU n 
2 270  LEU n 
2 271  LEU n 
2 272  HIS n 
2 273  THR n 
2 274  TYR n 
2 275  PRO n 
2 276  GLY n 
2 277  ASN n 
2 278  VAL n 
2 279  SER n 
2 280  THR n 
2 281  ILE n 
2 282  GLN n 
2 283  GLY n 
2 284  ARG n 
2 285  ASP n 
2 286  GLY n 
2 287  ARG n 
2 288  LYS n 
2 289  ASN n 
2 290  VAL n 
2 291  VAL n 
2 292  PRO n 
2 293  CYS n 
2 294  VAL n 
2 295  LEU n 
2 296  SER n 
2 297  VAL n 
2 298  SER n 
2 299  GLY n 
2 300  ASP n 
2 301  VAL n 
2 302  ASP n 
2 303  LEU n 
2 304  GLY n 
2 305  THR n 
2 306  LEU n 
2 307  ALA n 
2 308  TYR n 
2 309  LEU n 
2 310  TYR n 
2 311  ASP n 
2 312  SER n 
2 313  PHE n 
2 314  GLN n 
2 315  LEU n 
2 316  ALA n 
2 317  GLU n 
2 318  ASN n 
2 319  SER n 
2 320  PHE n 
2 321  ALA n 
2 322  ARG n 
2 323  LYS n 
2 324  LYS n 
2 325  SER n 
2 326  LEU n 
2 327  GLN n 
2 328  ARG n 
2 329  LYS n 
2 330  VAL n 
2 331  LEU n 
2 332  LYS n 
2 333  LEU n 
2 334  HIS n 
2 335  PRO n 
2 336  CYS n 
2 337  LEU n 
2 338  ALA n 
2 339  PRO n 
2 340  ILE n 
2 341  LYS n 
2 342  VAL n 
2 343  ALA n 
2 344  LEU n 
2 345  ASP n 
2 346  VAL n 
2 347  GLY n 
2 348  LYS n 
2 349  GLY n 
2 350  PRO n 
2 351  THR n 
2 352  VAL n 
2 353  GLU n 
2 354  LEU n 
2 355  ARG n 
2 356  GLN n 
2 357  VAL n 
2 358  CYS n 
2 359  GLN n 
2 360  GLY n 
2 361  LEU n 
2 362  LEU n 
2 363  ASN n 
2 364  GLU n 
2 365  LEU n 
2 366  LEU n 
2 367  GLU n 
2 368  ASN n 
2 369  GLY n 
2 370  ILE n 
2 371  SER n 
2 372  VAL n 
2 373  TRP n 
2 374  PRO n 
2 375  GLY n 
2 376  TYR n 
2 377  SER n 
2 378  GLU n 
2 379  THR n 
2 380  VAL n 
2 381  HIS n 
2 382  SER n 
2 383  SER n 
2 384  LEU n 
2 385  GLU n 
2 386  GLN n 
2 387  LEU n 
2 388  HIS n 
2 389  SER n 
2 390  LYS n 
2 391  TYR n 
2 392  ASP n 
2 393  GLU n 
2 394  MET n 
2 395  SER n 
2 396  VAL n 
2 397  LEU n 
2 398  PHE n 
2 399  SER n 
2 400  VAL n 
2 401  LEU n 
2 402  VAL n 
2 403  THR n 
2 404  GLU n 
2 405  THR n 
2 406  THR n 
2 407  LEU n 
2 408  GLU n 
2 409  ASN n 
2 410  GLY n 
2 411  LEU n 
2 412  ILE n 
2 413  GLN n 
2 414  LEU n 
2 415  ARG n 
2 416  SER n 
2 417  ARG n 
2 418  ASP n 
2 419  THR n 
2 420  THR n 
2 421  MET n 
2 422  LYS n 
2 423  GLU n 
2 424  MET n 
2 425  MET n 
2 426  HIS n 
2 427  ILE n 
2 428  SER n 
2 429  LYS n 
2 430  LEU n 
2 431  ARG n 
2 432  ASP n 
2 433  PHE n 
2 434  LEU n 
2 435  VAL n 
2 436  LYS n 
2 437  TYR n 
2 438  LEU n 
2 439  ALA n 
2 440  SER n 
2 441  ALA n 
2 442  SER n 
2 443  ASN n 
2 444  VAL n 
2 445  HIS n 
2 446  HIS n 
2 447  HIS n 
2 448  HIS n 
2 449  HIS n 
2 450  HIS n 
3 1    DG  n 
3 2    DC  n 
3 3    DA  n 
3 4    DT  n 
3 5    DG  n 
3 6    DC  n 
3 7    DG  n 
3 8    DG  n 
3 9    DT  n 
3 10   DC  n 
3 11   DG  n 
3 12   DA  n 
3 13   DG  n 
3 14   DT  n 
3 15   DC  n 
3 16   DT  n 
3 17   DA  n 
3 18   DG  n 
3 19   DA  n 
3 20   DG  n 
3 21   DG  n 
3 22   DA  n 
3 23   DG  n 
3 24   DC  n 
3 25   DT  n 
4 1    DT  n 
4 2    DT  n 
4 3    DT  n 
4 4    DT  n 
4 5    DT  n 
4 6    DT  n 
4 7    DT  n 
4 8    DT  n 
4 9    DT  n 
4 10   DT  n 
4 11   DA  n 
4 12   DT  n 
4 13   DC  n 
4 14   DC  n 
4 15   DG  n 
4 16   DG  n 
4 17   DG  n 
4 18   DC  n 
4 19   DT  n 
4 20   DC  n 
4 21   DC  n 
4 22   DT  n 
4 23   DC  n 
4 24   DT  n 
4 25   DA  n 
4 26   DG  n 
4 27   DA  n 
4 28   DC  n 
4 29   DT  n 
4 30   DC  n 
4 31   DG  n 
4 32   DA  n 
4 33   DC  n 
4 34   DC  n 
4 35   DG  n 
4 36   DC  n 
4 37   DA  n 
4 38   DT  n 
4 39   DG  n 
4 40   DC  n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 1221 human         ? 'POLG, MDP1, POLG1, POLGA' ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? 
? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 450  'house mouse' ? 'Polg2, Mtpolb'            ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? 
? 'Escherichia coli'      562  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_pdbx_entity_src_syn.entity_id 
_pdbx_entity_src_syn.pdbx_src_id 
_pdbx_entity_src_syn.pdbx_alt_source_flag 
_pdbx_entity_src_syn.pdbx_beg_seq_num 
_pdbx_entity_src_syn.pdbx_end_seq_num 
_pdbx_entity_src_syn.organism_scientific 
_pdbx_entity_src_syn.organism_common_name 
_pdbx_entity_src_syn.ncbi_taxonomy_id 
_pdbx_entity_src_syn.details 
3 1 sample 1 25 'synthetic construct' ? 32630 ? 
4 1 sample 1 40 'synthetic construct' ? 32630 ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                              ? 'C3 H7 N O2'       89.093  
ARG 'L-peptide linking' y ARGININE                             ? 'C6 H15 N4 O2 1'   175.209 
ASN 'L-peptide linking' y ASPARAGINE                           ? 'C4 H8 N2 O3'      132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                      ? 'C4 H7 N O4'       133.103 
CA  non-polymer         . 'CALCIUM ION'                        ? 'Ca 2'             40.078  
CYS 'L-peptide linking' y CYSTEINE                             ? 'C3 H7 N O2 S'     121.158 
DA  'DNA linking'       y "2'-DEOXYADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O6 P'  331.222 
DC  'DNA linking'       y "2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O7 P'   307.197 
DCP non-polymer         . "2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE"   ? 'C9 H16 N3 O13 P3' 467.157 
DG  'DNA linking'       y "2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P'  347.221 
DT  'DNA linking'       y "THYMIDINE-5'-MONOPHOSPHATE"         ? 'C10 H15 N2 O8 P'  322.208 
GLN 'L-peptide linking' y GLUTAMINE                            ? 'C5 H10 N2 O3'     146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                      ? 'C5 H9 N O4'       147.129 
GLY 'peptide linking'   y GLYCINE                              ? 'C2 H5 N O2'       75.067  
HIS 'L-peptide linking' y HISTIDINE                            ? 'C6 H10 N3 O2 1'   156.162 
ILE 'L-peptide linking' y ISOLEUCINE                           ? 'C6 H13 N O2'      131.173 
LEU 'L-peptide linking' y LEUCINE                              ? 'C6 H13 N O2'      131.173 
LYS 'L-peptide linking' y LYSINE                               ? 'C6 H15 N2 O2 1'   147.195 
MET 'L-peptide linking' y METHIONINE                           ? 'C5 H11 N O2 S'    149.211 
PHE 'L-peptide linking' y PHENYLALANINE                        ? 'C9 H11 N O2'      165.189 
PRO 'L-peptide linking' y PROLINE                              ? 'C5 H9 N O2'       115.130 
SER 'L-peptide linking' y SERINE                               ? 'C3 H7 N O3'       105.093 
THR 'L-peptide linking' y THREONINE                            ? 'C4 H9 N O3'       119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                           ? 'C11 H12 N2 O2'    204.225 
TYR 'L-peptide linking' y TYROSINE                             ? 'C9 H11 N O3'      181.189 
VAL 'L-peptide linking' y VALINE                               ? 'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1    MET 1    19   ?    ?   ?   A . n 
A 1 2    HIS 2    20   ?    ?   ?   A . n 
A 1 3    HIS 3    21   ?    ?   ?   A . n 
A 1 4    HIS 4    22   ?    ?   ?   A . n 
A 1 5    HIS 5    23   ?    ?   ?   A . n 
A 1 6    HIS 6    24   ?    ?   ?   A . n 
A 1 7    HIS 7    25   ?    ?   ?   A . n 
A 1 8    VAL 8    26   ?    ?   ?   A . n 
A 1 9    SER 9    27   ?    ?   ?   A . n 
A 1 10   SER 10   28   ?    ?   ?   A . n 
A 1 11   SER 11   29   ?    ?   ?   A . n 
A 1 12   VAL 12   30   ?    ?   ?   A . n 
A 1 13   PRO 13   31   ?    ?   ?   A . n 
A 1 14   ALA 14   32   ?    ?   ?   A . n 
A 1 15   SER 15   33   ?    ?   ?   A . n 
A 1 16   ASP 16   34   ?    ?   ?   A . n 
A 1 17   PRO 17   35   ?    ?   ?   A . n 
A 1 18   SER 18   36   ?    ?   ?   A . n 
A 1 19   ASP 19   37   ?    ?   ?   A . n 
A 1 20   GLY 20   38   ?    ?   ?   A . n 
A 1 21   GLN 21   39   ?    ?   ?   A . n 
A 1 22   ARG 22   40   ?    ?   ?   A . n 
A 1 23   ARG 23   41   ?    ?   ?   A . n 
A 1 24   ARG 24   42   ?    ?   ?   A . n 
A 1 25   GLN 25   43   ?    ?   ?   A . n 
A 1 26   GLN 26   44   ?    ?   ?   A . n 
A 1 27   GLN 27   45   ?    ?   ?   A . n 
A 1 28   GLN 28   46   ?    ?   ?   A . n 
A 1 29   GLN 29   47   ?    ?   ?   A . n 
A 1 30   GLN 30   48   ?    ?   ?   A . n 
A 1 31   GLN 31   49   ?    ?   ?   A . n 
A 1 32   GLN 32   50   ?    ?   ?   A . n 
A 1 33   GLN 33   51   ?    ?   ?   A . n 
A 1 34   GLN 34   52   ?    ?   ?   A . n 
A 1 35   GLN 35   53   ?    ?   ?   A . n 
A 1 36   GLN 36   54   ?    ?   ?   A . n 
A 1 37   GLN 37   55   ?    ?   ?   A . n 
A 1 38   PRO 38   56   ?    ?   ?   A . n 
A 1 39   GLN 39   57   ?    ?   ?   A . n 
A 1 40   GLN 40   58   ?    ?   ?   A . n 
A 1 41   PRO 41   59   ?    ?   ?   A . n 
A 1 42   GLN 42   60   ?    ?   ?   A . n 
A 1 43   VAL 43   61   ?    ?   ?   A . n 
A 1 44   LEU 44   62   ?    ?   ?   A . n 
A 1 45   SER 45   63   ?    ?   ?   A . n 
A 1 46   SER 46   64   ?    ?   ?   A . n 
A 1 47   GLU 47   65   ?    ?   ?   A . n 
A 1 48   GLY 48   66   ?    ?   ?   A . n 
A 1 49   GLY 49   67   ?    ?   ?   A . n 
A 1 50   GLN 50   68   ?    ?   ?   A . n 
A 1 51   LEU 51   69   ?    ?   ?   A . n 
A 1 52   ARG 52   70   70   ARG ARG A . n 
A 1 53   HIS 53   71   71   HIS HIS A . n 
A 1 54   ASN 54   72   72   ASN ASN A . n 
A 1 55   PRO 55   73   73   PRO PRO A . n 
A 1 56   LEU 56   74   74   LEU LEU A . n 
A 1 57   ASP 57   75   75   ASP ASP A . n 
A 1 58   ILE 58   76   76   ILE ILE A . n 
A 1 59   GLN 59   77   77   GLN GLN A . n 
A 1 60   MET 60   78   78   MET MET A . n 
A 1 61   LEU 61   79   79   LEU LEU A . n 
A 1 62   SER 62   80   80   SER SER A . n 
A 1 63   ARG 63   81   81   ARG ARG A . n 
A 1 64   GLY 64   82   82   GLY GLY A . n 
A 1 65   LEU 65   83   83   LEU LEU A . n 
A 1 66   HIS 66   84   84   HIS HIS A . n 
A 1 67   GLU 67   85   85   GLU GLU A . n 
A 1 68   GLN 68   86   86   GLN GLN A . n 
A 1 69   ILE 69   87   87   ILE ILE A . n 
A 1 70   PHE 70   88   88   PHE PHE A . n 
A 1 71   GLY 71   89   89   GLY GLY A . n 
A 1 72   GLN 72   90   90   GLN GLN A . n 
A 1 73   GLY 73   91   91   GLY GLY A . n 
A 1 74   GLY 74   92   92   GLY GLY A . n 
A 1 75   GLU 75   93   93   GLU GLU A . n 
A 1 76   MET 76   94   94   MET MET A . n 
A 1 77   PRO 77   95   95   PRO PRO A . n 
A 1 78   GLY 78   96   96   GLY GLY A . n 
A 1 79   GLU 79   97   97   GLU GLU A . n 
A 1 80   ALA 80   98   98   ALA ALA A . n 
A 1 81   ALA 81   99   99   ALA ALA A . n 
A 1 82   VAL 82   100  100  VAL VAL A . n 
A 1 83   ARG 83   101  101  ARG ARG A . n 
A 1 84   ARG 84   102  102  ARG ARG A . n 
A 1 85   SER 85   103  103  SER SER A . n 
A 1 86   VAL 86   104  104  VAL VAL A . n 
A 1 87   GLU 87   105  105  GLU GLU A . n 
A 1 88   HIS 88   106  106  HIS HIS A . n 
A 1 89   LEU 89   107  107  LEU LEU A . n 
A 1 90   GLN 90   108  108  GLN GLN A . n 
A 1 91   LYS 91   109  109  LYS LYS A . n 
A 1 92   HIS 92   110  110  HIS HIS A . n 
A 1 93   GLY 93   111  111  GLY GLY A . n 
A 1 94   LEU 94   112  112  LEU LEU A . n 
A 1 95   TRP 95   113  113  TRP TRP A . n 
A 1 96   GLY 96   114  114  GLY GLY A . n 
A 1 97   GLN 97   115  115  GLN GLN A . n 
A 1 98   PRO 98   116  116  PRO PRO A . n 
A 1 99   ALA 99   117  117  ALA ALA A . n 
A 1 100  VAL 100  118  118  VAL VAL A . n 
A 1 101  PRO 101  119  119  PRO PRO A . n 
A 1 102  LEU 102  120  120  LEU LEU A . n 
A 1 103  PRO 103  121  121  PRO PRO A . n 
A 1 104  ASP 104  122  122  ASP ASP A . n 
A 1 105  VAL 105  123  123  VAL VAL A . n 
A 1 106  GLU 106  124  124  GLU GLU A . n 
A 1 107  LEU 107  125  125  LEU LEU A . n 
A 1 108  ARG 108  126  126  ARG ARG A . n 
A 1 109  LEU 109  127  127  LEU LEU A . n 
A 1 110  PRO 110  128  128  PRO PRO A . n 
A 1 111  PRO 111  129  129  PRO PRO A . n 
A 1 112  LEU 112  130  130  LEU LEU A . n 
A 1 113  TYR 113  131  131  TYR TYR A . n 
A 1 114  GLY 114  132  132  GLY GLY A . n 
A 1 115  ASP 115  133  133  ASP ASP A . n 
A 1 116  ASN 116  134  134  ASN ASN A . n 
A 1 117  LEU 117  135  135  LEU LEU A . n 
A 1 118  ASP 118  136  136  ASP ASP A . n 
A 1 119  GLN 119  137  137  GLN GLN A . n 
A 1 120  HIS 120  138  138  HIS HIS A . n 
A 1 121  PHE 121  139  139  PHE PHE A . n 
A 1 122  ARG 122  140  140  ARG ARG A . n 
A 1 123  LEU 123  141  141  LEU LEU A . n 
A 1 124  LEU 124  142  142  LEU LEU A . n 
A 1 125  ALA 125  143  143  ALA ALA A . n 
A 1 126  GLN 126  144  144  GLN GLN A . n 
A 1 127  LYS 127  145  145  LYS LYS A . n 
A 1 128  GLN 128  146  146  GLN GLN A . n 
A 1 129  SER 129  147  147  SER SER A . n 
A 1 130  LEU 130  148  148  LEU LEU A . n 
A 1 131  PRO 131  149  149  PRO PRO A . n 
A 1 132  TYR 132  150  150  TYR TYR A . n 
A 1 133  LEU 133  151  151  LEU LEU A . n 
A 1 134  GLU 134  152  152  GLU GLU A . n 
A 1 135  ALA 135  153  153  ALA ALA A . n 
A 1 136  ALA 136  154  154  ALA ALA A . n 
A 1 137  ASN 137  155  155  ASN ASN A . n 
A 1 138  LEU 138  156  156  LEU LEU A . n 
A 1 139  LEU 139  157  157  LEU LEU A . n 
A 1 140  LEU 140  158  158  LEU LEU A . n 
A 1 141  GLN 141  159  159  GLN GLN A . n 
A 1 142  ALA 142  160  160  ALA ALA A . n 
A 1 143  GLN 143  161  161  GLN GLN A . n 
A 1 144  LEU 144  162  162  LEU LEU A . n 
A 1 145  PRO 145  163  163  PRO PRO A . n 
A 1 146  PRO 146  164  164  PRO PRO A . n 
A 1 147  LYS 147  165  165  LYS LYS A . n 
A 1 148  PRO 148  166  166  PRO PRO A . n 
A 1 149  PRO 149  167  167  PRO PRO A . n 
A 1 150  ALA 150  168  168  ALA ALA A . n 
A 1 151  TRP 151  169  169  TRP TRP A . n 
A 1 152  ALA 152  170  170  ALA ALA A . n 
A 1 153  TRP 153  171  171  TRP TRP A . n 
A 1 154  ALA 154  172  172  ALA ALA A . n 
A 1 155  GLU 155  173  173  GLU GLU A . n 
A 1 156  GLY 156  174  174  GLY GLY A . n 
A 1 157  TRP 157  175  175  TRP TRP A . n 
A 1 158  THR 158  176  176  THR THR A . n 
A 1 159  ARG 159  177  177  ARG ARG A . n 
A 1 160  TYR 160  178  178  TYR TYR A . n 
A 1 161  GLY 161  179  179  GLY GLY A . n 
A 1 162  PRO 162  180  180  PRO PRO A . n 
A 1 163  GLU 163  181  181  GLU GLU A . n 
A 1 164  GLY 164  182  182  GLY GLY A . n 
A 1 165  GLU 165  183  183  GLU GLU A . n 
A 1 166  ALA 166  184  184  ALA ALA A . n 
A 1 167  VAL 167  185  185  VAL VAL A . n 
A 1 168  PRO 168  186  186  PRO PRO A . n 
A 1 169  VAL 169  187  187  VAL VAL A . n 
A 1 170  ALA 170  188  188  ALA ALA A . n 
A 1 171  ILE 171  189  189  ILE ILE A . n 
A 1 172  PRO 172  190  190  PRO PRO A . n 
A 1 173  GLU 173  191  191  GLU GLU A . n 
A 1 174  GLU 174  192  192  GLU GLU A . n 
A 1 175  ARG 175  193  193  ARG ARG A . n 
A 1 176  ALA 176  194  194  ALA ALA A . n 
A 1 177  LEU 177  195  195  LEU LEU A . n 
A 1 178  VAL 178  196  196  VAL VAL A . n 
A 1 179  PHE 179  197  197  PHE PHE A . n 
A 1 180  ASP 180  198  198  ASP ASP A . n 
A 1 181  VAL 181  199  199  VAL VAL A . n 
A 1 182  GLU 182  200  200  GLU GLU A . n 
A 1 183  VAL 183  201  201  VAL VAL A . n 
A 1 184  CYS 184  202  202  CYS CYS A . n 
A 1 185  LEU 185  203  203  LEU LEU A . n 
A 1 186  ALA 186  204  204  ALA ALA A . n 
A 1 187  GLU 187  205  205  GLU GLU A . n 
A 1 188  GLY 188  206  206  GLY GLY A . n 
A 1 189  THR 189  207  207  THR THR A . n 
A 1 190  CYS 190  208  208  CYS CYS A . n 
A 1 191  PRO 191  209  209  PRO PRO A . n 
A 1 192  THR 192  210  210  THR THR A . n 
A 1 193  LEU 193  211  211  LEU LEU A . n 
A 1 194  ALA 194  212  212  ALA ALA A . n 
A 1 195  VAL 195  213  213  VAL VAL A . n 
A 1 196  ALA 196  214  214  ALA ALA A . n 
A 1 197  ILE 197  215  215  ILE ILE A . n 
A 1 198  SER 198  216  216  SER SER A . n 
A 1 199  PRO 199  217  217  PRO PRO A . n 
A 1 200  SER 200  218  218  SER SER A . n 
A 1 201  ALA 201  219  219  ALA ALA A . n 
A 1 202  TRP 202  220  220  TRP TRP A . n 
A 1 203  TYR 203  221  221  TYR TYR A . n 
A 1 204  SER 204  222  222  SER SER A . n 
A 1 205  TRP 205  223  223  TRP TRP A . n 
A 1 206  CYS 206  224  224  CYS CYS A . n 
A 1 207  SER 207  225  225  SER SER A . n 
A 1 208  GLN 208  226  226  GLN GLN A . n 
A 1 209  ARG 209  227  227  ARG ARG A . n 
A 1 210  LEU 210  228  228  LEU LEU A . n 
A 1 211  VAL 211  229  229  VAL VAL A . n 
A 1 212  GLU 212  230  230  GLU GLU A . n 
A 1 213  GLU 213  231  231  GLU GLU A . n 
A 1 214  ARG 214  232  232  ARG ARG A . n 
A 1 215  TYR 215  233  233  TYR TYR A . n 
A 1 216  SER 216  234  234  SER SER A . n 
A 1 217  TRP 217  235  235  TRP TRP A . n 
A 1 218  THR 218  236  236  THR THR A . n 
A 1 219  SER 219  237  237  SER SER A . n 
A 1 220  GLN 220  238  238  GLN GLN A . n 
A 1 221  LEU 221  239  239  LEU LEU A . n 
A 1 222  SER 222  240  240  SER SER A . n 
A 1 223  PRO 223  241  241  PRO PRO A . n 
A 1 224  ALA 224  242  242  ALA ALA A . n 
A 1 225  ASP 225  243  243  ASP ASP A . n 
A 1 226  LEU 226  244  244  LEU LEU A . n 
A 1 227  ILE 227  245  245  ILE ILE A . n 
A 1 228  PRO 228  246  246  PRO PRO A . n 
A 1 229  LEU 229  247  247  LEU LEU A . n 
A 1 230  GLU 230  248  248  GLU GLU A . n 
A 1 231  VAL 231  249  249  VAL VAL A . n 
A 1 232  PRO 232  250  250  PRO PRO A . n 
A 1 233  THR 233  251  ?    ?   ?   A . n 
A 1 234  GLY 234  252  ?    ?   ?   A . n 
A 1 235  ALA 235  253  ?    ?   ?   A . n 
A 1 236  SER 236  254  ?    ?   ?   A . n 
A 1 237  SER 237  255  ?    ?   ?   A . n 
A 1 238  PRO 238  256  ?    ?   ?   A . n 
A 1 239  THR 239  257  ?    ?   ?   A . n 
A 1 240  GLN 240  258  ?    ?   ?   A . n 
A 1 241  ARG 241  259  ?    ?   ?   A . n 
A 1 242  ASP 242  260  ?    ?   ?   A . n 
A 1 243  TRP 243  261  ?    ?   ?   A . n 
A 1 244  GLN 244  262  262  GLN GLN A . n 
A 1 245  GLU 245  263  263  GLU GLU A . n 
A 1 246  GLN 246  264  264  GLN GLN A . n 
A 1 247  LEU 247  265  265  LEU LEU A . n 
A 1 248  VAL 248  266  266  VAL VAL A . n 
A 1 249  VAL 249  267  267  VAL VAL A . n 
A 1 250  GLY 250  268  268  GLY GLY A . n 
A 1 251  HIS 251  269  269  HIS HIS A . n 
A 1 252  ASN 252  270  270  ASN ASN A . n 
A 1 253  VAL 253  271  271  VAL VAL A . n 
A 1 254  SER 254  272  272  SER SER A . n 
A 1 255  PHE 255  273  273  PHE PHE A . n 
A 1 256  ASP 256  274  274  ASP ASP A . n 
A 1 257  ARG 257  275  275  ARG ARG A . n 
A 1 258  ALA 258  276  276  ALA ALA A . n 
A 1 259  HIS 259  277  277  HIS HIS A . n 
A 1 260  ILE 260  278  278  ILE ILE A . n 
A 1 261  ARG 261  279  279  ARG ARG A . n 
A 1 262  GLU 262  280  280  GLU GLU A . n 
A 1 263  GLN 263  281  281  GLN GLN A . n 
A 1 264  TYR 264  282  282  TYR TYR A . n 
A 1 265  LEU 265  283  283  LEU LEU A . n 
A 1 266  ILE 266  284  284  ILE ILE A . n 
A 1 267  GLN 267  285  285  GLN GLN A . n 
A 1 268  GLY 268  286  286  GLY GLY A . n 
A 1 269  SER 269  287  287  SER SER A . n 
A 1 270  ARG 270  288  288  ARG ARG A . n 
A 1 271  MET 271  289  289  MET MET A . n 
A 1 272  ARG 272  290  290  ARG ARG A . n 
A 1 273  PHE 273  291  291  PHE PHE A . n 
A 1 274  LEU 274  292  292  LEU LEU A . n 
A 1 275  ASP 275  293  293  ASP ASP A . n 
A 1 276  THR 276  294  294  THR THR A . n 
A 1 277  MET 277  295  295  MET MET A . n 
A 1 278  SER 278  296  296  SER SER A . n 
A 1 279  MET 279  297  297  MET MET A . n 
A 1 280  HIS 280  298  298  HIS HIS A . n 
A 1 281  MET 281  299  299  MET MET A . n 
A 1 282  ALA 282  300  300  ALA ALA A . n 
A 1 283  ILE 283  301  301  ILE ILE A . n 
A 1 284  SER 284  302  302  SER SER A . n 
A 1 285  GLY 285  303  303  GLY GLY A . n 
A 1 286  LEU 286  304  304  LEU LEU A . n 
A 1 287  SER 287  305  305  SER SER A . n 
A 1 288  SER 288  306  306  SER SER A . n 
A 1 289  PHE 289  307  307  PHE PHE A . n 
A 1 290  GLN 290  308  308  GLN GLN A . n 
A 1 291  ARG 291  309  309  ARG ARG A . n 
A 1 292  SER 292  310  310  SER SER A . n 
A 1 293  LEU 293  311  311  LEU LEU A . n 
A 1 294  TRP 294  312  312  TRP TRP A . n 
A 1 295  ILE 295  313  313  ILE ILE A . n 
A 1 296  ALA 296  314  ?    ?   ?   A . n 
A 1 297  ALA 297  315  ?    ?   ?   A . n 
A 1 298  LYS 298  316  ?    ?   ?   A . n 
A 1 299  GLN 299  317  ?    ?   ?   A . n 
A 1 300  GLY 300  318  ?    ?   ?   A . n 
A 1 301  LYS 301  319  ?    ?   ?   A . n 
A 1 302  HIS 302  320  ?    ?   ?   A . n 
A 1 303  LYS 303  321  ?    ?   ?   A . n 
A 1 304  VAL 304  322  ?    ?   ?   A . n 
A 1 305  GLN 305  323  ?    ?   ?   A . n 
A 1 306  PRO 306  324  ?    ?   ?   A . n 
A 1 307  PRO 307  325  ?    ?   ?   A . n 
A 1 308  THR 308  326  ?    ?   ?   A . n 
A 1 309  LYS 309  327  ?    ?   ?   A . n 
A 1 310  GLN 310  328  ?    ?   ?   A . n 
A 1 311  GLY 311  329  ?    ?   ?   A . n 
A 1 312  GLN 312  330  ?    ?   ?   A . n 
A 1 313  LYS 313  331  ?    ?   ?   A . n 
A 1 314  SER 314  332  ?    ?   ?   A . n 
A 1 315  GLN 315  333  ?    ?   ?   A . n 
A 1 316  ARG 316  334  ?    ?   ?   A . n 
A 1 317  LYS 317  335  ?    ?   ?   A . n 
A 1 318  ALA 318  336  ?    ?   ?   A . n 
A 1 319  ARG 319  337  ?    ?   ?   A . n 
A 1 320  ARG 320  338  ?    ?   ?   A . n 
A 1 321  GLY 321  339  ?    ?   ?   A . n 
A 1 322  PRO 322  340  ?    ?   ?   A . n 
A 1 323  ALA 323  341  ?    ?   ?   A . n 
A 1 324  ILE 324  342  ?    ?   ?   A . n 
A 1 325  SER 325  343  ?    ?   ?   A . n 
A 1 326  SER 326  344  ?    ?   ?   A . n 
A 1 327  TRP 327  345  ?    ?   ?   A . n 
A 1 328  ASP 328  346  ?    ?   ?   A . n 
A 1 329  TRP 329  347  347  TRP TRP A . n 
A 1 330  LEU 330  348  348  LEU LEU A . n 
A 1 331  ASP 331  349  349  ASP ASP A . n 
A 1 332  ILE 332  350  350  ILE ILE A . n 
A 1 333  SER 333  351  351  SER SER A . n 
A 1 334  SER 334  352  352  SER SER A . n 
A 1 335  VAL 335  353  353  VAL VAL A . n 
A 1 336  ASN 336  354  354  ASN ASN A . n 
A 1 337  SER 337  355  355  SER SER A . n 
A 1 338  LEU 338  356  356  LEU LEU A . n 
A 1 339  ALA 339  357  357  ALA ALA A . n 
A 1 340  GLU 340  358  358  GLU GLU A . n 
A 1 341  VAL 341  359  359  VAL VAL A . n 
A 1 342  HIS 342  360  360  HIS HIS A . n 
A 1 343  ARG 343  361  361  ARG ARG A . n 
A 1 344  LEU 344  362  362  LEU LEU A . n 
A 1 345  TYR 345  363  363  TYR TYR A . n 
A 1 346  VAL 346  364  364  VAL VAL A . n 
A 1 347  GLY 347  365  365  GLY GLY A . n 
A 1 348  GLY 348  366  366  GLY GLY A . n 
A 1 349  PRO 349  367  367  PRO PRO A . n 
A 1 350  PRO 350  368  368  PRO PRO A . n 
A 1 351  LEU 351  369  369  LEU LEU A . n 
A 1 352  GLU 352  370  370  GLU GLU A . n 
A 1 353  LYS 353  371  371  LYS LYS A . n 
A 1 354  GLU 354  372  372  GLU GLU A . n 
A 1 355  PRO 355  373  373  PRO PRO A . n 
A 1 356  ARG 356  374  374  ARG ARG A . n 
A 1 357  GLU 357  375  375  GLU GLU A . n 
A 1 358  LEU 358  376  376  LEU LEU A . n 
A 1 359  PHE 359  377  377  PHE PHE A . n 
A 1 360  VAL 360  378  378  VAL VAL A . n 
A 1 361  LYS 361  379  379  LYS LYS A . n 
A 1 362  GLY 362  380  380  GLY GLY A . n 
A 1 363  THR 363  381  381  THR THR A . n 
A 1 364  MET 364  382  382  MET MET A . n 
A 1 365  LYS 365  383  383  LYS LYS A . n 
A 1 366  ASP 366  384  384  ASP ASP A . n 
A 1 367  ILE 367  385  385  ILE ILE A . n 
A 1 368  ARG 368  386  386  ARG ARG A . n 
A 1 369  GLU 369  387  387  GLU GLU A . n 
A 1 370  ASN 370  388  388  ASN ASN A . n 
A 1 371  PHE 371  389  389  PHE PHE A . n 
A 1 372  GLN 372  390  390  GLN GLN A . n 
A 1 373  ASP 373  391  391  ASP ASP A . n 
A 1 374  LEU 374  392  392  LEU LEU A . n 
A 1 375  MET 375  393  393  MET MET A . n 
A 1 376  GLN 376  394  394  GLN GLN A . n 
A 1 377  TYR 377  395  395  TYR TYR A . n 
A 1 378  CYS 378  396  396  CYS CYS A . n 
A 1 379  ALA 379  397  397  ALA ALA A . n 
A 1 380  GLN 380  398  398  GLN GLN A . n 
A 1 381  ASP 381  399  399  ASP ASP A . n 
A 1 382  VAL 382  400  400  VAL VAL A . n 
A 1 383  TRP 383  401  401  TRP TRP A . n 
A 1 384  ALA 384  402  402  ALA ALA A . n 
A 1 385  THR 385  403  403  THR THR A . n 
A 1 386  HIS 386  404  404  HIS HIS A . n 
A 1 387  GLU 387  405  405  GLU GLU A . n 
A 1 388  VAL 388  406  406  VAL VAL A . n 
A 1 389  PHE 389  407  407  PHE PHE A . n 
A 1 390  GLN 390  408  408  GLN GLN A . n 
A 1 391  GLN 391  409  409  GLN GLN A . n 
A 1 392  GLN 392  410  410  GLN GLN A . n 
A 1 393  LEU 393  411  411  LEU LEU A . n 
A 1 394  PRO 394  412  412  PRO PRO A . n 
A 1 395  LEU 395  413  413  LEU LEU A . n 
A 1 396  PHE 396  414  414  PHE PHE A . n 
A 1 397  LEU 397  415  415  LEU LEU A . n 
A 1 398  GLU 398  416  416  GLU GLU A . n 
A 1 399  ARG 399  417  417  ARG ARG A . n 
A 1 400  CYS 400  418  418  CYS CYS A . n 
A 1 401  PRO 401  419  419  PRO PRO A . n 
A 1 402  HIS 402  420  420  HIS HIS A . n 
A 1 403  PRO 403  421  421  PRO PRO A . n 
A 1 404  VAL 404  422  422  VAL VAL A . n 
A 1 405  THR 405  423  423  THR THR A . n 
A 1 406  LEU 406  424  424  LEU LEU A . n 
A 1 407  ALA 407  425  425  ALA ALA A . n 
A 1 408  GLY 408  426  426  GLY GLY A . n 
A 1 409  MET 409  427  427  MET MET A . n 
A 1 410  LEU 410  428  428  LEU LEU A . n 
A 1 411  GLU 411  429  429  GLU GLU A . n 
A 1 412  MET 412  430  430  MET MET A . n 
A 1 413  GLY 413  431  431  GLY GLY A . n 
A 1 414  VAL 414  432  432  VAL VAL A . n 
A 1 415  SER 415  433  433  SER SER A . n 
A 1 416  TYR 416  434  434  TYR TYR A . n 
A 1 417  LEU 417  435  435  LEU LEU A . n 
A 1 418  PRO 418  436  436  PRO PRO A . n 
A 1 419  VAL 419  437  437  VAL VAL A . n 
A 1 420  ASN 420  438  438  ASN ASN A . n 
A 1 421  GLN 421  439  439  GLN GLN A . n 
A 1 422  ASN 422  440  440  ASN ASN A . n 
A 1 423  TRP 423  441  441  TRP TRP A . n 
A 1 424  GLU 424  442  442  GLU GLU A . n 
A 1 425  ARG 425  443  443  ARG ARG A . n 
A 1 426  TYR 426  444  444  TYR TYR A . n 
A 1 427  LEU 427  445  445  LEU LEU A . n 
A 1 428  ALA 428  446  446  ALA ALA A . n 
A 1 429  GLU 429  447  447  GLU GLU A . n 
A 1 430  ALA 430  448  448  ALA ALA A . n 
A 1 431  GLN 431  449  449  GLN GLN A . n 
A 1 432  GLY 432  450  450  GLY GLY A . n 
A 1 433  THR 433  451  451  THR THR A . n 
A 1 434  TYR 434  452  452  TYR TYR A . n 
A 1 435  GLU 435  453  453  GLU GLU A . n 
A 1 436  GLU 436  454  454  GLU GLU A . n 
A 1 437  LEU 437  455  455  LEU LEU A . n 
A 1 438  GLN 438  456  456  GLN GLN A . n 
A 1 439  ARG 439  457  457  ARG ARG A . n 
A 1 440  GLU 440  458  458  GLU GLU A . n 
A 1 441  MET 441  459  459  MET MET A . n 
A 1 442  LYS 442  460  460  LYS LYS A . n 
A 1 443  LYS 443  461  461  LYS LYS A . n 
A 1 444  SER 444  462  462  SER SER A . n 
A 1 445  LEU 445  463  463  LEU LEU A . n 
A 1 446  MET 446  464  464  MET MET A . n 
A 1 447  ASP 447  465  465  ASP ASP A . n 
A 1 448  LEU 448  466  466  LEU LEU A . n 
A 1 449  ALA 449  467  467  ALA ALA A . n 
A 1 450  ASN 450  468  468  ASN ASN A . n 
A 1 451  ASP 451  469  469  ASP ASP A . n 
A 1 452  ALA 452  470  470  ALA ALA A . n 
A 1 453  CYS 453  471  471  CYS CYS A . n 
A 1 454  GLN 454  472  472  GLN GLN A . n 
A 1 455  LEU 455  473  473  LEU LEU A . n 
A 1 456  LEU 456  474  474  LEU LEU A . n 
A 1 457  SER 457  475  475  SER SER A . n 
A 1 458  GLY 458  476  476  GLY GLY A . n 
A 1 459  GLU 459  477  477  GLU GLU A . n 
A 1 460  ARG 460  478  478  ARG ARG A . n 
A 1 461  TYR 461  479  479  TYR TYR A . n 
A 1 462  LYS 462  480  480  LYS LYS A . n 
A 1 463  GLU 463  481  481  GLU GLU A . n 
A 1 464  ASP 464  482  482  ASP ASP A . n 
A 1 465  PRO 465  483  483  PRO PRO A . n 
A 1 466  TRP 466  484  484  TRP TRP A . n 
A 1 467  LEU 467  485  485  LEU LEU A . n 
A 1 468  TRP 468  486  486  TRP TRP A . n 
A 1 469  ASP 469  487  487  ASP ASP A . n 
A 1 470  LEU 470  488  488  LEU LEU A . n 
A 1 471  GLU 471  489  489  GLU GLU A . n 
A 1 472  TRP 472  490  490  TRP TRP A . n 
A 1 473  ASP 473  491  491  ASP ASP A . n 
A 1 474  LEU 474  492  492  LEU LEU A . n 
A 1 475  GLN 475  493  493  GLN GLN A . n 
A 1 476  GLU 476  494  494  GLU GLU A . n 
A 1 477  PHE 477  495  495  PHE PHE A . n 
A 1 478  LYS 478  496  496  LYS LYS A . n 
A 1 479  GLN 479  497  497  GLN GLN A . n 
A 1 480  LYS 480  498  498  LYS LYS A . n 
A 1 481  LYS 481  499  ?    ?   ?   A . n 
A 1 482  ALA 482  500  ?    ?   ?   A . n 
A 1 483  LYS 483  501  ?    ?   ?   A . n 
A 1 484  LYS 484  502  ?    ?   ?   A . n 
A 1 485  VAL 485  503  ?    ?   ?   A . n 
A 1 486  LYS 486  504  ?    ?   ?   A . n 
A 1 487  LYS 487  505  ?    ?   ?   A . n 
A 1 488  GLU 488  506  ?    ?   ?   A . n 
A 1 489  PRO 489  507  ?    ?   ?   A . n 
A 1 490  ALA 490  508  ?    ?   ?   A . n 
A 1 491  THR 491  509  ?    ?   ?   A . n 
A 1 492  ALA 492  510  ?    ?   ?   A . n 
A 1 493  SER 493  511  ?    ?   ?   A . n 
A 1 494  LYS 494  512  ?    ?   ?   A . n 
A 1 495  LEU 495  513  ?    ?   ?   A . n 
A 1 496  PRO 496  514  ?    ?   ?   A . n 
A 1 497  ILE 497  515  ?    ?   ?   A . n 
A 1 498  GLU 498  516  ?    ?   ?   A . n 
A 1 499  GLY 499  517  ?    ?   ?   A . n 
A 1 500  ALA 500  518  ?    ?   ?   A . n 
A 1 501  GLY 501  519  ?    ?   ?   A . n 
A 1 502  ALA 502  520  ?    ?   ?   A . n 
A 1 503  PRO 503  521  ?    ?   ?   A . n 
A 1 504  GLY 504  522  ?    ?   ?   A . n 
A 1 505  ASP 505  523  ?    ?   ?   A . n 
A 1 506  PRO 506  524  ?    ?   ?   A . n 
A 1 507  MET 507  525  ?    ?   ?   A . n 
A 1 508  ASP 508  526  ?    ?   ?   A . n 
A 1 509  GLN 509  527  ?    ?   ?   A . n 
A 1 510  GLU 510  528  ?    ?   ?   A . n 
A 1 511  ASP 511  529  ?    ?   ?   A . n 
A 1 512  LEU 512  530  530  LEU LEU A . n 
A 1 513  GLY 513  531  531  GLY GLY A . n 
A 1 514  PRO 514  532  532  PRO PRO A . n 
A 1 515  CYS 515  533  533  CYS CYS A . n 
A 1 516  SER 516  534  534  SER SER A . n 
A 1 517  GLU 517  535  535  GLU GLU A . n 
A 1 518  GLU 518  536  536  GLU GLU A . n 
A 1 519  GLU 519  537  537  GLU GLU A . n 
A 1 520  GLU 520  538  538  GLU GLU A . n 
A 1 521  PHE 521  539  539  PHE PHE A . n 
A 1 522  GLN 522  540  540  GLN GLN A . n 
A 1 523  GLN 523  541  541  GLN GLN A . n 
A 1 524  ASP 524  542  542  ASP ASP A . n 
A 1 525  VAL 525  543  543  VAL VAL A . n 
A 1 526  MET 526  544  544  MET MET A . n 
A 1 527  ALA 527  545  545  ALA ALA A . n 
A 1 528  ARG 528  546  546  ARG ARG A . n 
A 1 529  ALA 529  547  547  ALA ALA A . n 
A 1 530  CYS 530  548  548  CYS CYS A . n 
A 1 531  LEU 531  549  549  LEU LEU A . n 
A 1 532  GLN 532  550  550  GLN GLN A . n 
A 1 533  LYS 533  551  551  LYS LYS A . n 
A 1 534  LEU 534  552  552  LEU LEU A . n 
A 1 535  LYS 535  553  553  LYS LYS A . n 
A 1 536  GLY 536  554  554  GLY GLY A . n 
A 1 537  THR 537  555  555  THR THR A . n 
A 1 538  THR 538  556  556  THR THR A . n 
A 1 539  GLU 539  557  557  GLU GLU A . n 
A 1 540  LEU 540  558  558  LEU LEU A . n 
A 1 541  LEU 541  559  559  LEU LEU A . n 
A 1 542  PRO 542  560  560  PRO PRO A . n 
A 1 543  LYS 543  561  561  LYS LYS A . n 
A 1 544  ARG 544  562  562  ARG ARG A . n 
A 1 545  PRO 545  563  563  PRO PRO A . n 
A 1 546  GLN 546  564  564  GLN GLN A . n 
A 1 547  HIS 547  565  565  HIS HIS A . n 
A 1 548  LEU 548  566  566  LEU LEU A . n 
A 1 549  PRO 549  567  567  PRO PRO A . n 
A 1 550  GLY 550  568  568  GLY GLY A . n 
A 1 551  HIS 551  569  569  HIS HIS A . n 
A 1 552  PRO 552  570  570  PRO PRO A . n 
A 1 553  GLY 553  571  571  GLY GLY A . n 
A 1 554  TRP 554  572  572  TRP TRP A . n 
A 1 555  TYR 555  573  573  TYR TYR A . n 
A 1 556  ARG 556  574  574  ARG ARG A . n 
A 1 557  LYS 557  575  575  LYS LYS A . n 
A 1 558  LEU 558  576  576  LEU LEU A . n 
A 1 559  CYS 559  577  577  CYS CYS A . n 
A 1 560  PRO 560  578  578  PRO PRO A . n 
A 1 561  ARG 561  579  579  ARG ARG A . n 
A 1 562  LEU 562  580  580  LEU LEU A . n 
A 1 563  ASP 563  581  581  ASP ASP A . n 
A 1 564  ASP 564  582  582  ASP ASP A . n 
A 1 565  PRO 565  583  583  PRO PRO A . n 
A 1 566  ALA 566  584  584  ALA ALA A . n 
A 1 567  TRP 567  585  585  TRP TRP A . n 
A 1 568  THR 568  586  586  THR THR A . n 
A 1 569  PRO 569  587  587  PRO PRO A . n 
A 1 570  GLY 570  588  588  GLY GLY A . n 
A 1 571  PRO 571  589  589  PRO PRO A . n 
A 1 572  SER 572  590  590  SER SER A . n 
A 1 573  LEU 573  591  591  LEU LEU A . n 
A 1 574  LEU 574  592  592  LEU LEU A . n 
A 1 575  SER 575  593  593  SER SER A . n 
A 1 576  LEU 576  594  594  LEU LEU A . n 
A 1 577  GLN 577  595  595  GLN GLN A . n 
A 1 578  MET 578  596  596  MET MET A . n 
A 1 579  ARG 579  597  597  ARG ARG A . n 
A 1 580  VAL 580  598  598  VAL VAL A . n 
A 1 581  THR 581  599  599  THR THR A . n 
A 1 582  PRO 582  600  600  PRO PRO A . n 
A 1 583  LYS 583  601  601  LYS LYS A . n 
A 1 584  LEU 584  602  602  LEU LEU A . n 
A 1 585  MET 585  603  603  MET MET A . n 
A 1 586  ALA 586  604  604  ALA ALA A . n 
A 1 587  LEU 587  605  605  LEU LEU A . n 
A 1 588  THR 588  606  606  THR THR A . n 
A 1 589  TRP 589  607  607  TRP TRP A . n 
A 1 590  ASP 590  608  608  ASP ASP A . n 
A 1 591  GLY 591  609  609  GLY GLY A . n 
A 1 592  PHE 592  610  610  PHE PHE A . n 
A 1 593  PRO 593  611  611  PRO PRO A . n 
A 1 594  LEU 594  612  612  LEU LEU A . n 
A 1 595  HIS 595  613  613  HIS HIS A . n 
A 1 596  TYR 596  614  614  TYR TYR A . n 
A 1 597  SER 597  615  615  SER SER A . n 
A 1 598  GLU 598  616  616  GLU GLU A . n 
A 1 599  ARG 599  617  617  ARG ARG A . n 
A 1 600  HIS 600  618  618  HIS HIS A . n 
A 1 601  GLY 601  619  619  GLY GLY A . n 
A 1 602  TRP 602  620  620  TRP TRP A . n 
A 1 603  GLY 603  621  621  GLY GLY A . n 
A 1 604  TYR 604  622  622  TYR TYR A . n 
A 1 605  LEU 605  623  623  LEU LEU A . n 
A 1 606  VAL 606  624  624  VAL VAL A . n 
A 1 607  PRO 607  625  ?    ?   ?   A . n 
A 1 608  GLY 608  626  ?    ?   ?   A . n 
A 1 609  ARG 609  627  ?    ?   ?   A . n 
A 1 610  ARG 610  628  ?    ?   ?   A . n 
A 1 611  ASP 611  629  ?    ?   ?   A . n 
A 1 612  ASN 612  630  ?    ?   ?   A . n 
A 1 613  LEU 613  631  ?    ?   ?   A . n 
A 1 614  ALA 614  632  ?    ?   ?   A . n 
A 1 615  LYS 615  633  ?    ?   ?   A . n 
A 1 616  LEU 616  634  ?    ?   ?   A . n 
A 1 617  PRO 617  635  ?    ?   ?   A . n 
A 1 618  THR 618  636  ?    ?   ?   A . n 
A 1 619  GLY 619  637  ?    ?   ?   A . n 
A 1 620  THR 620  638  ?    ?   ?   A . n 
A 1 621  THR 621  639  ?    ?   ?   A . n 
A 1 622  LEU 622  640  ?    ?   ?   A . n 
A 1 623  GLU 623  641  ?    ?   ?   A . n 
A 1 624  SER 624  642  ?    ?   ?   A . n 
A 1 625  ALA 625  643  ?    ?   ?   A . n 
A 1 626  GLY 626  644  ?    ?   ?   A . n 
A 1 627  VAL 627  645  ?    ?   ?   A . n 
A 1 628  VAL 628  646  ?    ?   ?   A . n 
A 1 629  CYS 629  647  ?    ?   ?   A . n 
A 1 630  PRO 630  648  ?    ?   ?   A . n 
A 1 631  TYR 631  649  ?    ?   ?   A . n 
A 1 632  ARG 632  650  ?    ?   ?   A . n 
A 1 633  ALA 633  651  ?    ?   ?   A . n 
A 1 634  ILE 634  652  ?    ?   ?   A . n 
A 1 635  GLU 635  653  ?    ?   ?   A . n 
A 1 636  SER 636  654  ?    ?   ?   A . n 
A 1 637  LEU 637  655  ?    ?   ?   A . n 
A 1 638  TYR 638  656  ?    ?   ?   A . n 
A 1 639  ARG 639  657  ?    ?   ?   A . n 
A 1 640  LYS 640  658  ?    ?   ?   A . n 
A 1 641  HIS 641  659  ?    ?   ?   A . n 
A 1 642  CYS 642  660  ?    ?   ?   A . n 
A 1 643  LEU 643  661  ?    ?   ?   A . n 
A 1 644  GLU 644  662  ?    ?   ?   A . n 
A 1 645  GLN 645  663  ?    ?   ?   A . n 
A 1 646  GLY 646  664  ?    ?   ?   A . n 
A 1 647  LYS 647  665  ?    ?   ?   A . n 
A 1 648  GLN 648  666  ?    ?   ?   A . n 
A 1 649  GLN 649  667  ?    ?   ?   A . n 
A 1 650  LEU 650  668  ?    ?   ?   A . n 
A 1 651  MET 651  669  ?    ?   ?   A . n 
A 1 652  PRO 652  670  ?    ?   ?   A . n 
A 1 653  GLN 653  671  ?    ?   ?   A . n 
A 1 654  GLU 654  672  ?    ?   ?   A . n 
A 1 655  ALA 655  673  ?    ?   ?   A . n 
A 1 656  GLY 656  674  ?    ?   ?   A . n 
A 1 657  LEU 657  675  ?    ?   ?   A . n 
A 1 658  ALA 658  676  ?    ?   ?   A . n 
A 1 659  GLU 659  677  ?    ?   ?   A . n 
A 1 660  GLU 660  678  ?    ?   ?   A . n 
A 1 661  PHE 661  679  ?    ?   ?   A . n 
A 1 662  LEU 662  680  ?    ?   ?   A . n 
A 1 663  LEU 663  681  ?    ?   ?   A . n 
A 1 664  THR 664  682  ?    ?   ?   A . n 
A 1 665  ASP 665  683  ?    ?   ?   A . n 
A 1 666  ASN 666  684  ?    ?   ?   A . n 
A 1 667  SER 667  685  ?    ?   ?   A . n 
A 1 668  ALA 668  686  ?    ?   ?   A . n 
A 1 669  ILE 669  687  ?    ?   ?   A . n 
A 1 670  TRP 670  688  ?    ?   ?   A . n 
A 1 671  GLN 671  689  ?    ?   ?   A . n 
A 1 672  THR 672  690  ?    ?   ?   A . n 
A 1 673  VAL 673  691  ?    ?   ?   A . n 
A 1 674  GLU 674  692  ?    ?   ?   A . n 
A 1 675  GLU 675  693  ?    ?   ?   A . n 
A 1 676  LEU 676  694  ?    ?   ?   A . n 
A 1 677  ASP 677  695  ?    ?   ?   A . n 
A 1 678  TYR 678  696  ?    ?   ?   A . n 
A 1 679  LEU 679  697  ?    ?   ?   A . n 
A 1 680  GLU 680  698  ?    ?   ?   A . n 
A 1 681  VAL 681  699  ?    ?   ?   A . n 
A 1 682  GLU 682  700  ?    ?   ?   A . n 
A 1 683  ALA 683  701  ?    ?   ?   A . n 
A 1 684  GLU 684  702  ?    ?   ?   A . n 
A 1 685  ALA 685  703  ?    ?   ?   A . n 
A 1 686  LYS 686  704  ?    ?   ?   A . n 
A 1 687  MET 687  705  ?    ?   ?   A . n 
A 1 688  GLU 688  706  ?    ?   ?   A . n 
A 1 689  ASN 689  707  ?    ?   ?   A . n 
A 1 690  LEU 690  708  ?    ?   ?   A . n 
A 1 691  ARG 691  709  ?    ?   ?   A . n 
A 1 692  ALA 692  710  ?    ?   ?   A . n 
A 1 693  ALA 693  711  ?    ?   ?   A . n 
A 1 694  VAL 694  712  ?    ?   ?   A . n 
A 1 695  PRO 695  713  ?    ?   ?   A . n 
A 1 696  GLY 696  714  ?    ?   ?   A . n 
A 1 697  GLN 697  715  ?    ?   ?   A . n 
A 1 698  PRO 698  716  ?    ?   ?   A . n 
A 1 699  LEU 699  717  ?    ?   ?   A . n 
A 1 700  ALA 700  718  ?    ?   ?   A . n 
A 1 701  LEU 701  719  ?    ?   ?   A . n 
A 1 702  THR 702  720  ?    ?   ?   A . n 
A 1 703  ALA 703  721  ?    ?   ?   A . n 
A 1 704  ARG 704  722  ?    ?   ?   A . n 
A 1 705  GLY 705  723  ?    ?   ?   A . n 
A 1 706  GLY 706  724  ?    ?   ?   A . n 
A 1 707  PRO 707  725  ?    ?   ?   A . n 
A 1 708  LYS 708  726  ?    ?   ?   A . n 
A 1 709  ASP 709  727  ?    ?   ?   A . n 
A 1 710  THR 710  728  ?    ?   ?   A . n 
A 1 711  GLN 711  729  ?    ?   ?   A . n 
A 1 712  PRO 712  730  ?    ?   ?   A . n 
A 1 713  SER 713  731  ?    ?   ?   A . n 
A 1 714  TYR 714  732  ?    ?   ?   A . n 
A 1 715  HIS 715  733  ?    ?   ?   A . n 
A 1 716  HIS 716  734  ?    ?   ?   A . n 
A 1 717  GLY 717  735  ?    ?   ?   A . n 
A 1 718  ASN 718  736  736  ASN ASN A . n 
A 1 719  GLY 719  737  737  GLY GLY A . n 
A 1 720  PRO 720  738  738  PRO PRO A . n 
A 1 721  TYR 721  739  739  TYR TYR A . n 
A 1 722  ASN 722  740  740  ASN ASN A . n 
A 1 723  ASP 723  741  741  ASP ASP A . n 
A 1 724  VAL 724  742  742  VAL VAL A . n 
A 1 725  ASP 725  743  743  ASP ASP A . n 
A 1 726  ILE 726  744  744  ILE ILE A . n 
A 1 727  PRO 727  745  745  PRO PRO A . n 
A 1 728  GLY 728  746  746  GLY GLY A . n 
A 1 729  CYS 729  747  747  CYS CYS A . n 
A 1 730  TRP 730  748  748  TRP TRP A . n 
A 1 731  PHE 731  749  749  PHE PHE A . n 
A 1 732  PHE 732  750  750  PHE PHE A . n 
A 1 733  LYS 733  751  751  LYS LYS A . n 
A 1 734  LEU 734  752  752  LEU LEU A . n 
A 1 735  PRO 735  753  753  PRO PRO A . n 
A 1 736  HIS 736  754  754  HIS HIS A . n 
A 1 737  LYS 737  755  755  LYS LYS A . n 
A 1 738  ASP 738  756  756  ASP ASP A . n 
A 1 739  GLY 739  757  757  GLY GLY A . n 
A 1 740  ASN 740  758  758  ASN ASN A . n 
A 1 741  SER 741  759  759  SER SER A . n 
A 1 742  CYS 742  760  760  CYS CYS A . n 
A 1 743  ASN 743  761  761  ASN ASN A . n 
A 1 744  VAL 744  762  762  VAL VAL A . n 
A 1 745  GLY 745  763  763  GLY GLY A . n 
A 1 746  SER 746  764  764  SER SER A . n 
A 1 747  PRO 747  765  765  PRO PRO A . n 
A 1 748  PHE 748  766  766  PHE PHE A . n 
A 1 749  ALA 749  767  767  ALA ALA A . n 
A 1 750  LYS 750  768  768  LYS LYS A . n 
A 1 751  ASP 751  769  769  ASP ASP A . n 
A 1 752  PHE 752  770  770  PHE PHE A . n 
A 1 753  LEU 753  771  771  LEU LEU A . n 
A 1 754  PRO 754  772  772  PRO PRO A . n 
A 1 755  LYS 755  773  773  LYS LYS A . n 
A 1 756  MET 756  774  ?    ?   ?   A . n 
A 1 757  GLU 757  775  ?    ?   ?   A . n 
A 1 758  ASP 758  776  ?    ?   ?   A . n 
A 1 759  GLY 759  777  ?    ?   ?   A . n 
A 1 760  THR 760  778  ?    ?   ?   A . n 
A 1 761  LEU 761  779  779  LEU LEU A . n 
A 1 762  GLN 762  780  780  GLN GLN A . n 
A 1 763  ALA 763  781  781  ALA ALA A . n 
A 1 764  GLY 764  782  782  GLY GLY A . n 
A 1 765  PRO 765  783  783  PRO PRO A . n 
A 1 766  GLY 766  784  784  GLY GLY A . n 
A 1 767  GLY 767  785  785  GLY GLY A . n 
A 1 768  ALA 768  786  786  ALA ALA A . n 
A 1 769  SER 769  787  787  SER SER A . n 
A 1 770  GLY 770  788  788  GLY GLY A . n 
A 1 771  PRO 771  789  789  PRO PRO A . n 
A 1 772  ARG 772  790  790  ARG ARG A . n 
A 1 773  ALA 773  791  791  ALA ALA A . n 
A 1 774  LEU 774  792  792  LEU LEU A . n 
A 1 775  GLU 775  793  793  GLU GLU A . n 
A 1 776  ILE 776  794  794  ILE ILE A . n 
A 1 777  ASN 777  795  795  ASN ASN A . n 
A 1 778  LYS 778  796  796  LYS LYS A . n 
A 1 779  MET 779  797  797  MET MET A . n 
A 1 780  ILE 780  798  798  ILE ILE A . n 
A 1 781  SER 781  799  799  SER SER A . n 
A 1 782  PHE 782  800  800  PHE PHE A . n 
A 1 783  TRP 783  801  801  TRP TRP A . n 
A 1 784  ARG 784  802  802  ARG ARG A . n 
A 1 785  ASN 785  803  803  ASN ASN A . n 
A 1 786  ALA 786  804  804  ALA ALA A . n 
A 1 787  HIS 787  805  805  HIS HIS A . n 
A 1 788  LYS 788  806  806  LYS LYS A . n 
A 1 789  ARG 789  807  807  ARG ARG A . n 
A 1 790  ILE 790  808  808  ILE ILE A . n 
A 1 791  SER 791  809  809  SER SER A . n 
A 1 792  SER 792  810  810  SER SER A . n 
A 1 793  GLN 793  811  811  GLN GLN A . n 
A 1 794  MET 794  812  812  MET MET A . n 
A 1 795  VAL 795  813  813  VAL VAL A . n 
A 1 796  VAL 796  814  814  VAL VAL A . n 
A 1 797  TRP 797  815  815  TRP TRP A . n 
A 1 798  LEU 798  816  816  LEU LEU A . n 
A 1 799  PRO 799  817  817  PRO PRO A . n 
A 1 800  ARG 800  818  818  ARG ARG A . n 
A 1 801  SER 801  819  819  SER SER A . n 
A 1 802  ALA 802  820  820  ALA ALA A . n 
A 1 803  LEU 803  821  821  LEU LEU A . n 
A 1 804  PRO 804  822  822  PRO PRO A . n 
A 1 805  ARG 805  823  823  ARG ARG A . n 
A 1 806  ALA 806  824  824  ALA ALA A . n 
A 1 807  VAL 807  825  825  VAL VAL A . n 
A 1 808  ILE 808  826  826  ILE ILE A . n 
A 1 809  ARG 809  827  827  ARG ARG A . n 
A 1 810  HIS 810  828  828  HIS HIS A . n 
A 1 811  PRO 811  829  829  PRO PRO A . n 
A 1 812  ASP 812  830  830  ASP ASP A . n 
A 1 813  TYR 813  831  831  TYR TYR A . n 
A 1 814  ASP 814  832  832  ASP ASP A . n 
A 1 815  GLU 815  833  833  GLU GLU A . n 
A 1 816  GLU 816  834  834  GLU GLU A . n 
A 1 817  GLY 817  835  835  GLY GLY A . n 
A 1 818  LEU 818  836  836  LEU LEU A . n 
A 1 819  TYR 819  837  837  TYR TYR A . n 
A 1 820  GLY 820  838  838  GLY GLY A . n 
A 1 821  ALA 821  839  839  ALA ALA A . n 
A 1 822  ILE 822  840  840  ILE ILE A . n 
A 1 823  LEU 823  841  841  LEU LEU A . n 
A 1 824  PRO 824  842  842  PRO PRO A . n 
A 1 825  GLN 825  843  843  GLN GLN A . n 
A 1 826  VAL 826  844  844  VAL VAL A . n 
A 1 827  VAL 827  845  845  VAL VAL A . n 
A 1 828  THR 828  846  846  THR THR A . n 
A 1 829  ALA 829  847  847  ALA ALA A . n 
A 1 830  GLY 830  848  848  GLY GLY A . n 
A 1 831  THR 831  849  849  THR THR A . n 
A 1 832  ILE 832  850  850  ILE ILE A . n 
A 1 833  THR 833  851  851  THR THR A . n 
A 1 834  ARG 834  852  852  ARG ARG A . n 
A 1 835  ARG 835  853  853  ARG ARG A . n 
A 1 836  ALA 836  854  854  ALA ALA A . n 
A 1 837  VAL 837  855  855  VAL VAL A . n 
A 1 838  GLU 838  856  856  GLU GLU A . n 
A 1 839  PRO 839  857  857  PRO PRO A . n 
A 1 840  THR 840  858  858  THR THR A . n 
A 1 841  TRP 841  859  859  TRP TRP A . n 
A 1 842  LEU 842  860  860  LEU LEU A . n 
A 1 843  THR 843  861  861  THR THR A . n 
A 1 844  ALA 844  862  862  ALA ALA A . n 
A 1 845  SER 845  863  863  SER SER A . n 
A 1 846  ASN 846  864  864  ASN ASN A . n 
A 1 847  ALA 847  865  865  ALA ALA A . n 
A 1 848  ARG 848  866  866  ARG ARG A . n 
A 1 849  PRO 849  867  867  PRO PRO A . n 
A 1 850  ASP 850  868  868  ASP ASP A . n 
A 1 851  ARG 851  869  869  ARG ARG A . n 
A 1 852  VAL 852  870  870  VAL VAL A . n 
A 1 853  GLY 853  871  871  GLY GLY A . n 
A 1 854  SER 854  872  872  SER SER A . n 
A 1 855  GLU 855  873  873  GLU GLU A . n 
A 1 856  LEU 856  874  874  LEU LEU A . n 
A 1 857  LYS 857  875  875  LYS LYS A . n 
A 1 858  ALA 858  876  876  ALA ALA A . n 
A 1 859  MET 859  877  877  MET MET A . n 
A 1 860  VAL 860  878  878  VAL VAL A . n 
A 1 861  GLN 861  879  879  GLN GLN A . n 
A 1 862  ALA 862  880  880  ALA ALA A . n 
A 1 863  PRO 863  881  881  PRO PRO A . n 
A 1 864  PRO 864  882  882  PRO PRO A . n 
A 1 865  GLY 865  883  883  GLY GLY A . n 
A 1 866  TYR 866  884  884  TYR TYR A . n 
A 1 867  THR 867  885  885  THR THR A . n 
A 1 868  LEU 868  886  886  LEU LEU A . n 
A 1 869  VAL 869  887  887  VAL VAL A . n 
A 1 870  GLY 870  888  888  GLY GLY A . n 
A 1 871  ALA 871  889  889  ALA ALA A . n 
A 1 872  ASP 872  890  890  ASP ASP A . n 
A 1 873  VAL 873  891  891  VAL VAL A . n 
A 1 874  ASP 874  892  892  ASP ASP A . n 
A 1 875  SER 875  893  893  SER SER A . n 
A 1 876  GLN 876  894  894  GLN GLN A . n 
A 1 877  GLU 877  895  895  GLU GLU A . n 
A 1 878  LEU 878  896  896  LEU LEU A . n 
A 1 879  TRP 879  897  897  TRP TRP A . n 
A 1 880  ILE 880  898  898  ILE ILE A . n 
A 1 881  ALA 881  899  899  ALA ALA A . n 
A 1 882  ALA 882  900  900  ALA ALA A . n 
A 1 883  VAL 883  901  901  VAL VAL A . n 
A 1 884  LEU 884  902  902  LEU LEU A . n 
A 1 885  GLY 885  903  903  GLY GLY A . n 
A 1 886  ASP 886  904  904  ASP ASP A . n 
A 1 887  ALA 887  905  905  ALA ALA A . n 
A 1 888  HIS 888  906  906  HIS HIS A . n 
A 1 889  PHE 889  907  907  PHE PHE A . n 
A 1 890  ALA 890  908  908  ALA ALA A . n 
A 1 891  GLY 891  909  909  GLY GLY A . n 
A 1 892  MET 892  910  910  MET MET A . n 
A 1 893  HIS 893  911  911  HIS HIS A . n 
A 1 894  GLY 894  912  912  GLY GLY A . n 
A 1 895  CYS 895  913  913  CYS CYS A . n 
A 1 896  THR 896  914  914  THR THR A . n 
A 1 897  ALA 897  915  915  ALA ALA A . n 
A 1 898  PHE 898  916  916  PHE PHE A . n 
A 1 899  GLY 899  917  917  GLY GLY A . n 
A 1 900  TRP 900  918  918  TRP TRP A . n 
A 1 901  MET 901  919  919  MET MET A . n 
A 1 902  THR 902  920  920  THR THR A . n 
A 1 903  LEU 903  921  921  LEU LEU A . n 
A 1 904  GLN 904  922  922  GLN GLN A . n 
A 1 905  GLY 905  923  923  GLY GLY A . n 
A 1 906  ARG 906  924  924  ARG ARG A . n 
A 1 907  LYS 907  925  925  LYS LYS A . n 
A 1 908  SER 908  926  926  SER SER A . n 
A 1 909  ARG 909  927  927  ARG ARG A . n 
A 1 910  GLY 910  928  928  GLY GLY A . n 
A 1 911  THR 911  929  929  THR THR A . n 
A 1 912  ASP 912  930  930  ASP ASP A . n 
A 1 913  LEU 913  931  931  LEU LEU A . n 
A 1 914  HIS 914  932  932  HIS HIS A . n 
A 1 915  SER 915  933  933  SER SER A . n 
A 1 916  LYS 916  934  934  LYS LYS A . n 
A 1 917  THR 917  935  935  THR THR A . n 
A 1 918  ALA 918  936  936  ALA ALA A . n 
A 1 919  THR 919  937  937  THR THR A . n 
A 1 920  THR 920  938  938  THR THR A . n 
A 1 921  VAL 921  939  939  VAL VAL A . n 
A 1 922  GLY 922  940  940  GLY GLY A . n 
A 1 923  ILE 923  941  941  ILE ILE A . n 
A 1 924  SER 924  942  942  SER SER A . n 
A 1 925  ARG 925  943  943  ARG ARG A . n 
A 1 926  GLU 926  944  944  GLU GLU A . n 
A 1 927  HIS 927  945  945  HIS HIS A . n 
A 1 928  ALA 928  946  946  ALA ALA A . n 
A 1 929  LYS 929  947  947  LYS LYS A . n 
A 1 930  ILE 930  948  948  ILE ILE A . n 
A 1 931  PHE 931  949  949  PHE PHE A . n 
A 1 932  ASN 932  950  950  ASN ASN A . n 
A 1 933  TYR 933  951  951  TYR TYR A . n 
A 1 934  GLY 934  952  952  GLY GLY A . n 
A 1 935  ARG 935  953  953  ARG ARG A . n 
A 1 936  ILE 936  954  954  ILE ILE A . n 
A 1 937  TYR 937  955  955  TYR TYR A . n 
A 1 938  GLY 938  956  956  GLY GLY A . n 
A 1 939  ALA 939  957  957  ALA ALA A . n 
A 1 940  GLY 940  958  958  GLY GLY A . n 
A 1 941  GLN 941  959  959  GLN GLN A . n 
A 1 942  PRO 942  960  960  PRO PRO A . n 
A 1 943  PHE 943  961  961  PHE PHE A . n 
A 1 944  ALA 944  962  962  ALA ALA A . n 
A 1 945  GLU 945  963  963  GLU GLU A . n 
A 1 946  ARG 946  964  964  ARG ARG A . n 
A 1 947  LEU 947  965  965  LEU LEU A . n 
A 1 948  LEU 948  966  966  LEU LEU A . n 
A 1 949  MET 949  967  967  MET MET A . n 
A 1 950  GLN 950  968  968  GLN GLN A . n 
A 1 951  PHE 951  969  969  PHE PHE A . n 
A 1 952  ASN 952  970  970  ASN ASN A . n 
A 1 953  HIS 953  971  971  HIS HIS A . n 
A 1 954  ARG 954  972  972  ARG ARG A . n 
A 1 955  LEU 955  973  973  LEU LEU A . n 
A 1 956  THR 956  974  974  THR THR A . n 
A 1 957  GLN 957  975  975  GLN GLN A . n 
A 1 958  GLN 958  976  976  GLN GLN A . n 
A 1 959  GLU 959  977  977  GLU GLU A . n 
A 1 960  ALA 960  978  978  ALA ALA A . n 
A 1 961  ALA 961  979  979  ALA ALA A . n 
A 1 962  GLU 962  980  980  GLU GLU A . n 
A 1 963  LYS 963  981  981  LYS LYS A . n 
A 1 964  ALA 964  982  982  ALA ALA A . n 
A 1 965  GLN 965  983  983  GLN GLN A . n 
A 1 966  GLN 966  984  984  GLN GLN A . n 
A 1 967  MET 967  985  985  MET MET A . n 
A 1 968  TYR 968  986  986  TYR TYR A . n 
A 1 969  ALA 969  987  987  ALA ALA A . n 
A 1 970  ALA 970  988  988  ALA ALA A . n 
A 1 971  THR 971  989  989  THR THR A . n 
A 1 972  LYS 972  990  990  LYS LYS A . n 
A 1 973  GLY 973  991  991  GLY GLY A . n 
A 1 974  LEU 974  992  992  LEU LEU A . n 
A 1 975  ARG 975  993  993  ARG ARG A . n 
A 1 976  TRP 976  994  ?    ?   ?   A . n 
A 1 977  TYR 977  995  ?    ?   ?   A . n 
A 1 978  ARG 978  996  ?    ?   ?   A . n 
A 1 979  LEU 979  997  ?    ?   ?   A . n 
A 1 980  SER 980  998  ?    ?   ?   A . n 
A 1 981  ASP 981  999  ?    ?   ?   A . n 
A 1 982  GLU 982  1000 ?    ?   ?   A . n 
A 1 983  GLY 983  1001 ?    ?   ?   A . n 
A 1 984  GLU 984  1002 ?    ?   ?   A . n 
A 1 985  TRP 985  1003 ?    ?   ?   A . n 
A 1 986  LEU 986  1004 ?    ?   ?   A . n 
A 1 987  VAL 987  1005 ?    ?   ?   A . n 
A 1 988  ARG 988  1006 ?    ?   ?   A . n 
A 1 989  GLU 989  1007 ?    ?   ?   A . n 
A 1 990  LEU 990  1008 ?    ?   ?   A . n 
A 1 991  ASN 991  1009 ?    ?   ?   A . n 
A 1 992  LEU 992  1010 ?    ?   ?   A . n 
A 1 993  PRO 993  1011 ?    ?   ?   A . n 
A 1 994  VAL 994  1012 ?    ?   ?   A . n 
A 1 995  ASP 995  1013 ?    ?   ?   A . n 
A 1 996  ARG 996  1014 ?    ?   ?   A . n 
A 1 997  THR 997  1015 ?    ?   ?   A . n 
A 1 998  GLU 998  1016 ?    ?   ?   A . n 
A 1 999  GLY 999  1017 ?    ?   ?   A . n 
A 1 1000 GLY 1000 1018 ?    ?   ?   A . n 
A 1 1001 TRP 1001 1019 ?    ?   ?   A . n 
A 1 1002 ILE 1002 1020 ?    ?   ?   A . n 
A 1 1003 SER 1003 1021 ?    ?   ?   A . n 
A 1 1004 LEU 1004 1022 ?    ?   ?   A . n 
A 1 1005 GLN 1005 1023 ?    ?   ?   A . n 
A 1 1006 ASP 1006 1024 ?    ?   ?   A . n 
A 1 1007 LEU 1007 1025 ?    ?   ?   A . n 
A 1 1008 ARG 1008 1026 ?    ?   ?   A . n 
A 1 1009 LYS 1009 1027 ?    ?   ?   A . n 
A 1 1010 VAL 1010 1028 ?    ?   ?   A . n 
A 1 1011 GLN 1011 1029 ?    ?   ?   A . n 
A 1 1012 ARG 1012 1030 ?    ?   ?   A . n 
A 1 1013 GLU 1013 1031 ?    ?   ?   A . n 
A 1 1014 THR 1014 1032 ?    ?   ?   A . n 
A 1 1015 ALA 1015 1033 ?    ?   ?   A . n 
A 1 1016 ARG 1016 1034 ?    ?   ?   A . n 
A 1 1017 LYS 1017 1035 ?    ?   ?   A . n 
A 1 1018 SER 1018 1036 ?    ?   ?   A . n 
A 1 1019 GLN 1019 1037 ?    ?   ?   A . n 
A 1 1020 TRP 1020 1038 ?    ?   ?   A . n 
A 1 1021 LYS 1021 1039 ?    ?   ?   A . n 
A 1 1022 LYS 1022 1040 ?    ?   ?   A . n 
A 1 1023 TRP 1023 1041 ?    ?   ?   A . n 
A 1 1024 GLU 1024 1042 ?    ?   ?   A . n 
A 1 1025 VAL 1025 1043 ?    ?   ?   A . n 
A 1 1026 VAL 1026 1044 ?    ?   ?   A . n 
A 1 1027 ALA 1027 1045 ?    ?   ?   A . n 
A 1 1028 GLU 1028 1046 ?    ?   ?   A . n 
A 1 1029 ARG 1029 1047 ?    ?   ?   A . n 
A 1 1030 ALA 1030 1048 ?    ?   ?   A . n 
A 1 1031 TRP 1031 1049 1049 TRP TRP A . n 
A 1 1032 LYS 1032 1050 1050 LYS LYS A . n 
A 1 1033 GLY 1033 1051 1051 GLY GLY A . n 
A 1 1034 GLY 1034 1052 1052 GLY GLY A . n 
A 1 1035 THR 1035 1053 1053 THR THR A . n 
A 1 1036 GLU 1036 1054 1054 GLU GLU A . n 
A 1 1037 SER 1037 1055 1055 SER SER A . n 
A 1 1038 GLU 1038 1056 1056 GLU GLU A . n 
A 1 1039 MET 1039 1057 1057 MET MET A . n 
A 1 1040 PHE 1040 1058 1058 PHE PHE A . n 
A 1 1041 ASN 1041 1059 1059 ASN ASN A . n 
A 1 1042 LYS 1042 1060 1060 LYS LYS A . n 
A 1 1043 LEU 1043 1061 1061 LEU LEU A . n 
A 1 1044 GLU 1044 1062 1062 GLU GLU A . n 
A 1 1045 SER 1045 1063 1063 SER SER A . n 
A 1 1046 ILE 1046 1064 1064 ILE ILE A . n 
A 1 1047 ALA 1047 1065 1065 ALA ALA A . n 
A 1 1048 THR 1048 1066 1066 THR THR A . n 
A 1 1049 SER 1049 1067 1067 SER SER A . n 
A 1 1050 ASP 1050 1068 1068 ASP ASP A . n 
A 1 1051 ILE 1051 1069 1069 ILE ILE A . n 
A 1 1052 PRO 1052 1070 1070 PRO PRO A . n 
A 1 1053 ARG 1053 1071 1071 ARG ARG A . n 
A 1 1054 THR 1054 1072 1072 THR THR A . n 
A 1 1055 PRO 1055 1073 1073 PRO PRO A . n 
A 1 1056 VAL 1056 1074 1074 VAL VAL A . n 
A 1 1057 LEU 1057 1075 1075 LEU LEU A . n 
A 1 1058 GLY 1058 1076 1076 GLY GLY A . n 
A 1 1059 CYS 1059 1077 1077 CYS CYS A . n 
A 1 1060 CYS 1060 1078 1078 CYS CYS A . n 
A 1 1061 ILE 1061 1079 1079 ILE ILE A . n 
A 1 1062 SER 1062 1080 1080 SER SER A . n 
A 1 1063 ARG 1063 1081 1081 ARG ARG A . n 
A 1 1064 ALA 1064 1082 1082 ALA ALA A . n 
A 1 1065 LEU 1065 1083 1083 LEU LEU A . n 
A 1 1066 GLU 1066 1084 1084 GLU GLU A . n 
A 1 1067 PRO 1067 1085 1085 PRO PRO A . n 
A 1 1068 SER 1068 1086 1086 SER SER A . n 
A 1 1069 ALA 1069 1087 1087 ALA ALA A . n 
A 1 1070 VAL 1070 1088 1088 VAL VAL A . n 
A 1 1071 GLN 1071 1089 1089 GLN GLN A . n 
A 1 1072 GLU 1072 1090 1090 GLU GLU A . n 
A 1 1073 GLU 1073 1091 1091 GLU GLU A . n 
A 1 1074 PHE 1074 1092 1092 PHE PHE A . n 
A 1 1075 MET 1075 1093 1093 MET MET A . n 
A 1 1076 THR 1076 1094 1094 THR THR A . n 
A 1 1077 SER 1077 1095 1095 SER SER A . n 
A 1 1078 ARG 1078 1096 1096 ARG ARG A . n 
A 1 1079 VAL 1079 1097 1097 VAL VAL A . n 
A 1 1080 ASN 1080 1098 1098 ASN ASN A . n 
A 1 1081 TRP 1081 1099 1099 TRP TRP A . n 
A 1 1082 VAL 1082 1100 1100 VAL VAL A . n 
A 1 1083 VAL 1083 1101 1101 VAL VAL A . n 
A 1 1084 GLN 1084 1102 1102 GLN GLN A . n 
A 1 1085 SER 1085 1103 1103 SER SER A . n 
A 1 1086 SER 1086 1104 1104 SER SER A . n 
A 1 1087 ALA 1087 1105 1105 ALA ALA A . n 
A 1 1088 VAL 1088 1106 1106 VAL VAL A . n 
A 1 1089 ASP 1089 1107 1107 ASP ASP A . n 
A 1 1090 TYR 1090 1108 1108 TYR TYR A . n 
A 1 1091 LEU 1091 1109 1109 LEU LEU A . n 
A 1 1092 HIS 1092 1110 1110 HIS HIS A . n 
A 1 1093 LEU 1093 1111 1111 LEU LEU A . n 
A 1 1094 MET 1094 1112 1112 MET MET A . n 
A 1 1095 LEU 1095 1113 1113 LEU LEU A . n 
A 1 1096 VAL 1096 1114 1114 VAL VAL A . n 
A 1 1097 ALA 1097 1115 1115 ALA ALA A . n 
A 1 1098 MET 1098 1116 1116 MET MET A . n 
A 1 1099 LYS 1099 1117 1117 LYS LYS A . n 
A 1 1100 TRP 1100 1118 1118 TRP TRP A . n 
A 1 1101 LEU 1101 1119 1119 LEU LEU A . n 
A 1 1102 PHE 1102 1120 1120 PHE PHE A . n 
A 1 1103 GLU 1103 1121 1121 GLU GLU A . n 
A 1 1104 GLU 1104 1122 1122 GLU GLU A . n 
A 1 1105 PHE 1105 1123 1123 PHE PHE A . n 
A 1 1106 ALA 1106 1124 1124 ALA ALA A . n 
A 1 1107 ILE 1107 1125 1125 ILE ILE A . n 
A 1 1108 ASP 1108 1126 1126 ASP ASP A . n 
A 1 1109 GLY 1109 1127 1127 GLY GLY A . n 
A 1 1110 ARG 1110 1128 1128 ARG ARG A . n 
A 1 1111 PHE 1111 1129 1129 PHE PHE A . n 
A 1 1112 CYS 1112 1130 1130 CYS CYS A . n 
A 1 1113 ILE 1113 1131 1131 ILE ILE A . n 
A 1 1114 SER 1114 1132 1132 SER SER A . n 
A 1 1115 ILE 1115 1133 1133 ILE ILE A . n 
A 1 1116 HIS 1116 1134 1134 HIS HIS A . n 
A 1 1117 ASP 1117 1135 1135 ASP ASP A . n 
A 1 1118 GLU 1118 1136 1136 GLU GLU A . n 
A 1 1119 VAL 1119 1137 1137 VAL VAL A . n 
A 1 1120 ARG 1120 1138 1138 ARG ARG A . n 
A 1 1121 TYR 1121 1139 1139 TYR TYR A . n 
A 1 1122 LEU 1122 1140 1140 LEU LEU A . n 
A 1 1123 VAL 1123 1141 1141 VAL VAL A . n 
A 1 1124 ARG 1124 1142 1142 ARG ARG A . n 
A 1 1125 GLU 1125 1143 1143 GLU GLU A . n 
A 1 1126 GLU 1126 1144 1144 GLU GLU A . n 
A 1 1127 ASP 1127 1145 1145 ASP ASP A . n 
A 1 1128 ARG 1128 1146 1146 ARG ARG A . n 
A 1 1129 TYR 1129 1147 1147 TYR TYR A . n 
A 1 1130 ARG 1130 1148 1148 ARG ARG A . n 
A 1 1131 ALA 1131 1149 1149 ALA ALA A . n 
A 1 1132 ALA 1132 1150 1150 ALA ALA A . n 
A 1 1133 LEU 1133 1151 1151 LEU LEU A . n 
A 1 1134 ALA 1134 1152 1152 ALA ALA A . n 
A 1 1135 LEU 1135 1153 1153 LEU LEU A . n 
A 1 1136 GLN 1136 1154 1154 GLN GLN A . n 
A 1 1137 ILE 1137 1155 1155 ILE ILE A . n 
A 1 1138 THR 1138 1156 1156 THR THR A . n 
A 1 1139 ASN 1139 1157 1157 ASN ASN A . n 
A 1 1140 LEU 1140 1158 1158 LEU LEU A . n 
A 1 1141 LEU 1141 1159 1159 LEU LEU A . n 
A 1 1142 THR 1142 1160 1160 THR THR A . n 
A 1 1143 ARG 1143 1161 1161 ARG ARG A . n 
A 1 1144 CYS 1144 1162 1162 CYS CYS A . n 
A 1 1145 MET 1145 1163 1163 MET MET A . n 
A 1 1146 PHE 1146 1164 1164 PHE PHE A . n 
A 1 1147 ALA 1147 1165 1165 ALA ALA A . n 
A 1 1148 TYR 1148 1166 1166 TYR TYR A . n 
A 1 1149 LYS 1149 1167 1167 LYS LYS A . n 
A 1 1150 LEU 1150 1168 1168 LEU LEU A . n 
A 1 1151 GLY 1151 1169 1169 GLY GLY A . n 
A 1 1152 LEU 1152 1170 1170 LEU LEU A . n 
A 1 1153 ASN 1153 1171 1171 ASN ASN A . n 
A 1 1154 ASP 1154 1172 1172 ASP ASP A . n 
A 1 1155 LEU 1155 1173 1173 LEU LEU A . n 
A 1 1156 PRO 1156 1174 1174 PRO PRO A . n 
A 1 1157 GLN 1157 1175 1175 GLN GLN A . n 
A 1 1158 SER 1158 1176 1176 SER SER A . n 
A 1 1159 VAL 1159 1177 1177 VAL VAL A . n 
A 1 1160 ALA 1160 1178 1178 ALA ALA A . n 
A 1 1161 PHE 1161 1179 1179 PHE PHE A . n 
A 1 1162 PHE 1162 1180 1180 PHE PHE A . n 
A 1 1163 SER 1163 1181 1181 SER SER A . n 
A 1 1164 ALA 1164 1182 1182 ALA ALA A . n 
A 1 1165 VAL 1165 1183 1183 VAL VAL A . n 
A 1 1166 ASP 1166 1184 1184 ASP ASP A . n 
A 1 1167 ILE 1167 1185 1185 ILE ILE A . n 
A 1 1168 ASP 1168 1186 1186 ASP ASP A . n 
A 1 1169 ARG 1169 1187 1187 ARG ARG A . n 
A 1 1170 CYS 1170 1188 1188 CYS CYS A . n 
A 1 1171 LEU 1171 1189 1189 LEU LEU A . n 
A 1 1172 ARG 1172 1190 1190 ARG ARG A . n 
A 1 1173 LYS 1173 1191 1191 LYS LYS A . n 
A 1 1174 GLU 1174 1192 1192 GLU GLU A . n 
A 1 1175 VAL 1175 1193 1193 VAL VAL A . n 
A 1 1176 THR 1176 1194 1194 THR THR A . n 
A 1 1177 MET 1177 1195 1195 MET MET A . n 
A 1 1178 ASP 1178 1196 1196 ASP ASP A . n 
A 1 1179 CYS 1179 1197 1197 CYS CYS A . n 
A 1 1180 LYS 1180 1198 1198 LYS LYS A . n 
A 1 1181 THR 1181 1199 1199 THR THR A . n 
A 1 1182 PRO 1182 1200 1200 PRO PRO A . n 
A 1 1183 SER 1183 1201 1201 SER SER A . n 
A 1 1184 ASN 1184 1202 1202 ASN ASN A . n 
A 1 1185 PRO 1185 1203 1203 PRO PRO A . n 
A 1 1186 THR 1186 1204 1204 THR THR A . n 
A 1 1187 GLY 1187 1205 1205 GLY GLY A . n 
A 1 1188 MET 1188 1206 1206 MET MET A . n 
A 1 1189 GLU 1189 1207 1207 GLU GLU A . n 
A 1 1190 ARG 1190 1208 1208 ARG ARG A . n 
A 1 1191 ARG 1191 1209 1209 ARG ARG A . n 
A 1 1192 TYR 1192 1210 1210 TYR TYR A . n 
A 1 1193 GLY 1193 1211 1211 GLY GLY A . n 
A 1 1194 ILE 1194 1212 1212 ILE ILE A . n 
A 1 1195 PRO 1195 1213 1213 PRO PRO A . n 
A 1 1196 GLN 1196 1214 1214 GLN GLN A . n 
A 1 1197 GLY 1197 1215 1215 GLY GLY A . n 
A 1 1198 GLU 1198 1216 1216 GLU GLU A . n 
A 1 1199 ALA 1199 1217 1217 ALA ALA A . n 
A 1 1200 LEU 1200 1218 1218 LEU LEU A . n 
A 1 1201 ASP 1201 1219 1219 ASP ASP A . n 
A 1 1202 ILE 1202 1220 1220 ILE ILE A . n 
A 1 1203 TYR 1203 1221 1221 TYR TYR A . n 
A 1 1204 GLN 1204 1222 1222 GLN GLN A . n 
A 1 1205 ILE 1205 1223 1223 ILE ILE A . n 
A 1 1206 ILE 1206 1224 1224 ILE ILE A . n 
A 1 1207 GLU 1207 1225 1225 GLU GLU A . n 
A 1 1208 LEU 1208 1226 1226 LEU LEU A . n 
A 1 1209 THR 1209 1227 1227 THR THR A . n 
A 1 1210 LYS 1210 1228 1228 LYS LYS A . n 
A 1 1211 GLY 1211 1229 1229 GLY GLY A . n 
A 1 1212 SER 1212 1230 1230 SER SER A . n 
A 1 1213 LEU 1213 1231 1231 LEU LEU A . n 
A 1 1214 GLU 1214 1232 1232 GLU GLU A . n 
A 1 1215 LYS 1215 1233 1233 LYS LYS A . n 
A 1 1216 ARG 1216 1234 ?    ?   ?   A . n 
A 1 1217 SER 1217 1235 ?    ?   ?   A . n 
A 1 1218 GLN 1218 1236 ?    ?   ?   A . n 
A 1 1219 PRO 1219 1237 ?    ?   ?   A . n 
A 1 1220 GLY 1220 1238 ?    ?   ?   A . n 
A 1 1221 PRO 1221 1239 ?    ?   ?   A . n 
B 2 1    MET 1    16   ?    ?   ?   B . n 
B 2 2    TRP 2    17   ?    ?   ?   B . n 
B 2 3    LEU 3    18   ?    ?   ?   B . n 
B 2 4    SER 4    19   ?    ?   ?   B . n 
B 2 5    GLY 5    20   ?    ?   ?   B . n 
B 2 6    TYR 6    21   ?    ?   ?   B . n 
B 2 7    ALA 7    22   ?    ?   ?   B . n 
B 2 8    GLY 8    23   ?    ?   ?   B . n 
B 2 9    PRO 9    24   ?    ?   ?   B . n 
B 2 10   ALA 10   25   ?    ?   ?   B . n 
B 2 11   ASP 11   26   ?    ?   ?   B . n 
B 2 12   GLY 12   27   ?    ?   ?   B . n 
B 2 13   THR 13   28   ?    ?   ?   B . n 
B 2 14   GLN 14   29   ?    ?   ?   B . n 
B 2 15   GLN 15   30   ?    ?   ?   B . n 
B 2 16   PRO 16   31   ?    ?   ?   B . n 
B 2 17   ASP 17   32   ?    ?   ?   B . n 
B 2 18   ALA 18   33   ?    ?   ?   B . n 
B 2 19   PRO 19   34   ?    ?   ?   B . n 
B 2 20   GLU 20   35   ?    ?   ?   B . n 
B 2 21   HIS 21   36   ?    ?   ?   B . n 
B 2 22   ALA 22   37   ?    ?   ?   B . n 
B 2 23   VAL 23   38   ?    ?   ?   B . n 
B 2 24   ALA 24   39   ?    ?   ?   B . n 
B 2 25   ARG 25   40   ?    ?   ?   B . n 
B 2 26   GLU 26   41   41   GLU GLU B . n 
B 2 27   ALA 27   42   42   ALA ALA B . n 
B 2 28   LEU 28   43   43   LEU LEU B . n 
B 2 29   VAL 29   44   44   VAL VAL B . n 
B 2 30   ASP 30   45   45   ASP ASP B . n 
B 2 31   LEU 31   46   46   LEU LEU B . n 
B 2 32   CYS 32   47   47   CYS CYS B . n 
B 2 33   ARG 33   48   48   ARG ARG B . n 
B 2 34   ARG 34   49   49   ARG ARG B . n 
B 2 35   ARG 35   50   50   ARG ARG B . n 
B 2 36   HIS 36   51   51   HIS HIS B . n 
B 2 37   PHE 37   52   52   PHE PHE B . n 
B 2 38   PHE 38   53   53   PHE PHE B . n 
B 2 39   SER 39   54   54   SER SER B . n 
B 2 40   GLY 40   55   55   GLY GLY B . n 
B 2 41   THR 41   56   56   THR THR B . n 
B 2 42   PRO 42   57   57   PRO PRO B . n 
B 2 43   GLN 43   58   58   GLN GLN B . n 
B 2 44   GLN 44   59   59   GLN GLN B . n 
B 2 45   LEU 45   60   60   LEU LEU B . n 
B 2 46   SER 46   61   61   SER SER B . n 
B 2 47   THR 47   62   62   THR THR B . n 
B 2 48   ALA 48   63   63   ALA ALA B . n 
B 2 49   ALA 49   64   64   ALA ALA B . n 
B 2 50   LEU 50   65   65   LEU LEU B . n 
B 2 51   LEU 51   66   66   LEU LEU B . n 
B 2 52   SER 52   67   67   SER SER B . n 
B 2 53   GLY 53   68   68   GLY GLY B . n 
B 2 54   CYS 54   69   69   CYS CYS B . n 
B 2 55   HIS 55   70   70   HIS HIS B . n 
B 2 56   ALA 56   71   71   ALA ALA B . n 
B 2 57   ARG 57   72   72   ARG ARG B . n 
B 2 58   PHE 58   73   73   PHE PHE B . n 
B 2 59   GLY 59   74   74   GLY GLY B . n 
B 2 60   PRO 60   75   75   PRO PRO B . n 
B 2 61   LEU 61   76   76   LEU LEU B . n 
B 2 62   GLY 62   77   77   GLY GLY B . n 
B 2 63   VAL 63   78   78   VAL VAL B . n 
B 2 64   GLU 64   79   79   GLU GLU B . n 
B 2 65   LEU 65   80   80   LEU LEU B . n 
B 2 66   ARG 66   81   81   ARG ARG B . n 
B 2 67   LYS 67   82   82   LYS LYS B . n 
B 2 68   ASN 68   83   83   ASN ASN B . n 
B 2 69   LEU 69   84   84   LEU LEU B . n 
B 2 70   ALA 70   85   85   ALA ALA B . n 
B 2 71   SER 71   86   86   SER SER B . n 
B 2 72   GLN 72   87   87   GLN GLN B . n 
B 2 73   TRP 73   88   88   TRP TRP B . n 
B 2 74   TRP 74   89   89   TRP TRP B . n 
B 2 75   SER 75   90   90   SER SER B . n 
B 2 76   SER 76   91   91   SER SER B . n 
B 2 77   MET 77   92   92   MET MET B . n 
B 2 78   VAL 78   93   93   VAL VAL B . n 
B 2 79   VAL 79   94   94   VAL VAL B . n 
B 2 80   PHE 80   95   95   PHE PHE B . n 
B 2 81   ARG 81   96   96   ARG ARG B . n 
B 2 82   GLU 82   97   97   GLU GLU B . n 
B 2 83   GLN 83   98   98   GLN GLN B . n 
B 2 84   VAL 84   99   99   VAL VAL B . n 
B 2 85   PHE 85   100  100  PHE PHE B . n 
B 2 86   ALA 86   101  101  ALA ALA B . n 
B 2 87   VAL 87   102  102  VAL VAL B . n 
B 2 88   ASP 88   103  103  ASP ASP B . n 
B 2 89   SER 89   104  104  SER SER B . n 
B 2 90   LEU 90   105  105  LEU LEU B . n 
B 2 91   HIS 91   106  106  HIS HIS B . n 
B 2 92   GLN 92   107  107  GLN GLN B . n 
B 2 93   GLU 93   108  108  GLU GLU B . n 
B 2 94   PRO 94   109  109  PRO PRO B . n 
B 2 95   GLY 95   110  110  GLY GLY B . n 
B 2 96   SER 96   111  ?    ?   ?   B . n 
B 2 97   SER 97   112  ?    ?   ?   B . n 
B 2 98   GLN 98   113  ?    ?   ?   B . n 
B 2 99   PRO 99   114  ?    ?   ?   B . n 
B 2 100  ARG 100  115  ?    ?   ?   B . n 
B 2 101  ASP 101  116  116  ASP ASP B . n 
B 2 102  SER 102  117  117  SER SER B . n 
B 2 103  ALA 103  118  118  ALA ALA B . n 
B 2 104  PHE 104  119  119  PHE PHE B . n 
B 2 105  ARG 105  120  120  ARG ARG B . n 
B 2 106  LEU 106  121  121  LEU LEU B . n 
B 2 107  VAL 107  122  122  VAL VAL B . n 
B 2 108  SER 108  123  123  SER SER B . n 
B 2 109  PRO 109  124  124  PRO PRO B . n 
B 2 110  GLU 110  125  125  GLU GLU B . n 
B 2 111  SER 111  126  126  SER SER B . n 
B 2 112  ILE 112  127  127  ILE ILE B . n 
B 2 113  ARG 113  128  ?    ?   ?   B . n 
B 2 114  GLU 114  129  ?    ?   ?   B . n 
B 2 115  ILE 115  130  ?    ?   ?   B . n 
B 2 116  LEU 116  131  ?    ?   ?   B . n 
B 2 117  GLN 117  132  ?    ?   ?   B . n 
B 2 118  ASP 118  133  ?    ?   ?   B . n 
B 2 119  ARG 119  134  ?    ?   ?   B . n 
B 2 120  GLU 120  135  ?    ?   ?   B . n 
B 2 121  PRO 121  136  ?    ?   ?   B . n 
B 2 122  SER 122  137  ?    ?   ?   B . n 
B 2 123  LYS 123  138  ?    ?   ?   B . n 
B 2 124  GLU 124  139  ?    ?   ?   B . n 
B 2 125  GLN 125  140  ?    ?   ?   B . n 
B 2 126  LEU 126  141  ?    ?   ?   B . n 
B 2 127  VAL 127  142  ?    ?   ?   B . n 
B 2 128  ALA 128  143  ?    ?   ?   B . n 
B 2 129  PHE 129  144  ?    ?   ?   B . n 
B 2 130  LEU 130  145  145  LEU LEU B . n 
B 2 131  GLU 131  146  146  GLU GLU B . n 
B 2 132  ASN 132  147  147  ASN ASN B . n 
B 2 133  LEU 133  148  148  LEU LEU B . n 
B 2 134  LEU 134  149  149  LEU LEU B . n 
B 2 135  LYS 135  150  150  LYS LYS B . n 
B 2 136  THR 136  151  151  THR THR B . n 
B 2 137  SER 137  152  152  SER SER B . n 
B 2 138  GLY 138  153  153  GLY GLY B . n 
B 2 139  LYS 139  154  154  LYS LYS B . n 
B 2 140  LEU 140  155  155  LEU LEU B . n 
B 2 141  ARG 141  156  156  ARG ARG B . n 
B 2 142  ALA 142  157  157  ALA ALA B . n 
B 2 143  THR 143  158  158  THR THR B . n 
B 2 144  LEU 144  159  159  LEU LEU B . n 
B 2 145  LEU 145  160  160  LEU LEU B . n 
B 2 146  HIS 146  161  161  HIS HIS B . n 
B 2 147  GLY 147  162  162  GLY GLY B . n 
B 2 148  ALA 148  163  163  ALA ALA B . n 
B 2 149  LEU 149  164  164  LEU LEU B . n 
B 2 150  GLU 150  165  165  GLU GLU B . n 
B 2 151  HIS 151  166  166  HIS HIS B . n 
B 2 152  TYR 152  167  167  TYR TYR B . n 
B 2 153  VAL 153  168  168  VAL VAL B . n 
B 2 154  ASN 154  169  169  ASN ASN B . n 
B 2 155  CYS 155  170  ?    ?   ?   B . n 
B 2 156  LEU 156  171  ?    ?   ?   B . n 
B 2 157  ASP 157  172  ?    ?   ?   B . n 
B 2 158  LEU 158  173  ?    ?   ?   B . n 
B 2 159  VAL 159  174  ?    ?   ?   B . n 
B 2 160  ASN 160  175  ?    ?   ?   B . n 
B 2 161  ARG 161  176  176  ARG ARG B . n 
B 2 162  LYS 162  177  177  LYS LYS B . n 
B 2 163  LEU 163  178  178  LEU LEU B . n 
B 2 164  PRO 164  179  179  PRO PRO B . n 
B 2 165  PHE 165  180  180  PHE PHE B . n 
B 2 166  GLY 166  181  181  GLY GLY B . n 
B 2 167  LEU 167  182  182  LEU LEU B . n 
B 2 168  ALA 168  183  183  ALA ALA B . n 
B 2 169  GLN 169  184  184  GLN GLN B . n 
B 2 170  ILE 170  185  185  ILE ILE B . n 
B 2 171  GLY 171  186  186  GLY GLY B . n 
B 2 172  VAL 172  187  187  VAL VAL B . n 
B 2 173  CYS 173  188  188  CYS CYS B . n 
B 2 174  PHE 174  189  189  PHE PHE B . n 
B 2 175  HIS 175  190  190  HIS HIS B . n 
B 2 176  PRO 176  191  191  PRO PRO B . n 
B 2 177  VAL 177  192  192  VAL VAL B . n 
B 2 178  SER 178  193  ?    ?   ?   B . n 
B 2 179  ASN 179  194  ?    ?   ?   B . n 
B 2 180  SER 180  195  ?    ?   ?   B . n 
B 2 181  ASN 181  196  ?    ?   ?   B . n 
B 2 182  GLN 182  197  ?    ?   ?   B . n 
B 2 183  THR 183  198  ?    ?   ?   B . n 
B 2 184  PRO 184  199  ?    ?   ?   B . n 
B 2 185  SER 185  200  ?    ?   ?   B . n 
B 2 186  SER 186  201  ?    ?   ?   B . n 
B 2 187  VAL 187  202  ?    ?   ?   B . n 
B 2 188  THR 188  203  203  THR THR B . n 
B 2 189  ARG 189  204  204  ARG ARG B . n 
B 2 190  VAL 190  205  205  VAL VAL B . n 
B 2 191  GLY 191  206  206  GLY GLY B . n 
B 2 192  GLU 192  207  207  GLU GLU B . n 
B 2 193  LYS 193  208  208  LYS LYS B . n 
B 2 194  THR 194  209  209  THR THR B . n 
B 2 195  GLU 195  210  210  GLU GLU B . n 
B 2 196  ALA 196  211  211  ALA ALA B . n 
B 2 197  SER 197  212  212  SER SER B . n 
B 2 198  LEU 198  213  213  LEU LEU B . n 
B 2 199  VAL 199  214  214  VAL VAL B . n 
B 2 200  TRP 200  215  215  TRP TRP B . n 
B 2 201  PHE 201  216  216  PHE PHE B . n 
B 2 202  THR 202  217  217  THR THR B . n 
B 2 203  PRO 203  218  218  PRO PRO B . n 
B 2 204  THR 204  219  219  THR THR B . n 
B 2 205  ARG 205  220  220  ARG ARG B . n 
B 2 206  THR 206  221  221  THR THR B . n 
B 2 207  SER 207  222  222  SER SER B . n 
B 2 208  SER 208  223  223  SER SER B . n 
B 2 209  GLN 209  224  224  GLN GLN B . n 
B 2 210  TRP 210  225  225  TRP TRP B . n 
B 2 211  LEU 211  226  226  LEU LEU B . n 
B 2 212  ASP 212  227  227  ASP ASP B . n 
B 2 213  PHE 213  228  228  PHE PHE B . n 
B 2 214  TRP 214  229  229  TRP TRP B . n 
B 2 215  LEU 215  230  230  LEU LEU B . n 
B 2 216  ARG 216  231  231  ARG ARG B . n 
B 2 217  HIS 217  232  232  HIS HIS B . n 
B 2 218  ARG 218  233  233  ARG ARG B . n 
B 2 219  LEU 219  234  234  LEU LEU B . n 
B 2 220  LEU 220  235  235  LEU LEU B . n 
B 2 221  TRP 221  236  236  TRP TRP B . n 
B 2 222  TRP 222  237  237  TRP TRP B . n 
B 2 223  ARG 223  238  238  ARG ARG B . n 
B 2 224  LYS 224  239  239  LYS LYS B . n 
B 2 225  PHE 225  240  240  PHE PHE B . n 
B 2 226  ALA 226  241  241  ALA ALA B . n 
B 2 227  MET 227  242  242  MET MET B . n 
B 2 228  SER 228  243  243  SER SER B . n 
B 2 229  PRO 229  244  244  PRO PRO B . n 
B 2 230  SER 230  245  245  SER SER B . n 
B 2 231  ASN 231  246  246  ASN ASN B . n 
B 2 232  PHE 232  247  247  PHE PHE B . n 
B 2 233  SER 233  248  248  SER SER B . n 
B 2 234  SER 234  249  249  SER SER B . n 
B 2 235  ALA 235  250  250  ALA ALA B . n 
B 2 236  ASP 236  251  251  ASP ASP B . n 
B 2 237  CYS 237  252  252  CYS CYS B . n 
B 2 238  GLN 238  253  253  GLN GLN B . n 
B 2 239  ASP 239  254  254  ASP ASP B . n 
B 2 240  GLU 240  255  255  GLU GLU B . n 
B 2 241  LEU 241  256  256  LEU LEU B . n 
B 2 242  GLY 242  257  257  GLY GLY B . n 
B 2 243  ARG 243  258  258  ARG ARG B . n 
B 2 244  LYS 244  259  259  LYS LYS B . n 
B 2 245  GLY 245  260  260  GLY GLY B . n 
B 2 246  SER 246  261  261  SER SER B . n 
B 2 247  LYS 247  262  262  LYS LYS B . n 
B 2 248  LEU 248  263  263  LEU LEU B . n 
B 2 249  TYR 249  264  264  TYR TYR B . n 
B 2 250  TYR 250  265  265  TYR TYR B . n 
B 2 251  SER 251  266  266  SER SER B . n 
B 2 252  PHE 252  267  267  PHE PHE B . n 
B 2 253  PRO 253  268  268  PRO PRO B . n 
B 2 254  TRP 254  269  269  TRP TRP B . n 
B 2 255  GLY 255  270  270  GLY GLY B . n 
B 2 256  LYS 256  271  271  LYS LYS B . n 
B 2 257  GLU 257  272  272  GLU GLU B . n 
B 2 258  PRO 258  273  273  PRO PRO B . n 
B 2 259  ILE 259  274  274  ILE ILE B . n 
B 2 260  GLU 260  275  275  GLU GLU B . n 
B 2 261  THR 261  276  276  THR THR B . n 
B 2 262  LEU 262  277  277  LEU LEU B . n 
B 2 263  TRP 263  278  278  TRP TRP B . n 
B 2 264  ASN 264  279  279  ASN ASN B . n 
B 2 265  LEU 265  280  280  LEU LEU B . n 
B 2 266  GLY 266  281  281  GLY GLY B . n 
B 2 267  ASP 267  282  282  ASP ASP B . n 
B 2 268  GLN 268  283  283  GLN GLN B . n 
B 2 269  GLU 269  284  284  GLU GLU B . n 
B 2 270  LEU 270  285  285  LEU LEU B . n 
B 2 271  LEU 271  286  286  LEU LEU B . n 
B 2 272  HIS 272  287  287  HIS HIS B . n 
B 2 273  THR 273  288  288  THR THR B . n 
B 2 274  TYR 274  289  289  TYR TYR B . n 
B 2 275  PRO 275  290  290  PRO PRO B . n 
B 2 276  GLY 276  291  291  GLY GLY B . n 
B 2 277  ASN 277  292  292  ASN ASN B . n 
B 2 278  VAL 278  293  293  VAL VAL B . n 
B 2 279  SER 279  294  294  SER SER B . n 
B 2 280  THR 280  295  295  THR THR B . n 
B 2 281  ILE 281  296  296  ILE ILE B . n 
B 2 282  GLN 282  297  ?    ?   ?   B . n 
B 2 283  GLY 283  298  ?    ?   ?   B . n 
B 2 284  ARG 284  299  ?    ?   ?   B . n 
B 2 285  ASP 285  300  ?    ?   ?   B . n 
B 2 286  GLY 286  301  ?    ?   ?   B . n 
B 2 287  ARG 287  302  ?    ?   ?   B . n 
B 2 288  LYS 288  303  ?    ?   ?   B . n 
B 2 289  ASN 289  304  304  ASN ASN B . n 
B 2 290  VAL 290  305  305  VAL VAL B . n 
B 2 291  VAL 291  306  306  VAL VAL B . n 
B 2 292  PRO 292  307  307  PRO PRO B . n 
B 2 293  CYS 293  308  308  CYS CYS B . n 
B 2 294  VAL 294  309  309  VAL VAL B . n 
B 2 295  LEU 295  310  310  LEU LEU B . n 
B 2 296  SER 296  311  311  SER SER B . n 
B 2 297  VAL 297  312  312  VAL VAL B . n 
B 2 298  SER 298  313  313  SER SER B . n 
B 2 299  GLY 299  314  314  GLY GLY B . n 
B 2 300  ASP 300  315  315  ASP ASP B . n 
B 2 301  VAL 301  316  316  VAL VAL B . n 
B 2 302  ASP 302  317  317  ASP ASP B . n 
B 2 303  LEU 303  318  318  LEU LEU B . n 
B 2 304  GLY 304  319  319  GLY GLY B . n 
B 2 305  THR 305  320  320  THR THR B . n 
B 2 306  LEU 306  321  321  LEU LEU B . n 
B 2 307  ALA 307  322  322  ALA ALA B . n 
B 2 308  TYR 308  323  323  TYR TYR B . n 
B 2 309  LEU 309  324  324  LEU LEU B . n 
B 2 310  TYR 310  325  325  TYR TYR B . n 
B 2 311  ASP 311  326  326  ASP ASP B . n 
B 2 312  SER 312  327  327  SER SER B . n 
B 2 313  PHE 313  328  328  PHE PHE B . n 
B 2 314  GLN 314  329  329  GLN GLN B . n 
B 2 315  LEU 315  330  330  LEU LEU B . n 
B 2 316  ALA 316  331  ?    ?   ?   B . n 
B 2 317  GLU 317  332  ?    ?   ?   B . n 
B 2 318  ASN 318  333  ?    ?   ?   B . n 
B 2 319  SER 319  334  ?    ?   ?   B . n 
B 2 320  PHE 320  335  ?    ?   ?   B . n 
B 2 321  ALA 321  336  ?    ?   ?   B . n 
B 2 322  ARG 322  337  ?    ?   ?   B . n 
B 2 323  LYS 323  338  ?    ?   ?   B . n 
B 2 324  LYS 324  339  ?    ?   ?   B . n 
B 2 325  SER 325  340  ?    ?   ?   B . n 
B 2 326  LEU 326  341  ?    ?   ?   B . n 
B 2 327  GLN 327  342  342  GLN GLN B . n 
B 2 328  ARG 328  343  343  ARG ARG B . n 
B 2 329  LYS 329  344  344  LYS LYS B . n 
B 2 330  VAL 330  345  345  VAL VAL B . n 
B 2 331  LEU 331  346  346  LEU LEU B . n 
B 2 332  LYS 332  347  347  LYS LYS B . n 
B 2 333  LEU 333  348  348  LEU LEU B . n 
B 2 334  HIS 334  349  349  HIS HIS B . n 
B 2 335  PRO 335  350  350  PRO PRO B . n 
B 2 336  CYS 336  351  351  CYS CYS B . n 
B 2 337  LEU 337  352  352  LEU LEU B . n 
B 2 338  ALA 338  353  353  ALA ALA B . n 
B 2 339  PRO 339  354  354  PRO PRO B . n 
B 2 340  ILE 340  355  355  ILE ILE B . n 
B 2 341  LYS 341  356  356  LYS LYS B . n 
B 2 342  VAL 342  357  357  VAL VAL B . n 
B 2 343  ALA 343  358  358  ALA ALA B . n 
B 2 344  LEU 344  359  359  LEU LEU B . n 
B 2 345  ASP 345  360  360  ASP ASP B . n 
B 2 346  VAL 346  361  361  VAL VAL B . n 
B 2 347  GLY 347  362  362  GLY GLY B . n 
B 2 348  LYS 348  363  363  LYS LYS B . n 
B 2 349  GLY 349  364  364  GLY GLY B . n 
B 2 350  PRO 350  365  365  PRO PRO B . n 
B 2 351  THR 351  366  366  THR THR B . n 
B 2 352  VAL 352  367  367  VAL VAL B . n 
B 2 353  GLU 353  368  368  GLU GLU B . n 
B 2 354  LEU 354  369  369  LEU LEU B . n 
B 2 355  ARG 355  370  370  ARG ARG B . n 
B 2 356  GLN 356  371  371  GLN GLN B . n 
B 2 357  VAL 357  372  372  VAL VAL B . n 
B 2 358  CYS 358  373  373  CYS CYS B . n 
B 2 359  GLN 359  374  374  GLN GLN B . n 
B 2 360  GLY 360  375  375  GLY GLY B . n 
B 2 361  LEU 361  376  376  LEU LEU B . n 
B 2 362  LEU 362  377  377  LEU LEU B . n 
B 2 363  ASN 363  378  378  ASN ASN B . n 
B 2 364  GLU 364  379  379  GLU GLU B . n 
B 2 365  LEU 365  380  380  LEU LEU B . n 
B 2 366  LEU 366  381  381  LEU LEU B . n 
B 2 367  GLU 367  382  382  GLU GLU B . n 
B 2 368  ASN 368  383  383  ASN ASN B . n 
B 2 369  GLY 369  384  384  GLY GLY B . n 
B 2 370  ILE 370  385  385  ILE ILE B . n 
B 2 371  SER 371  386  386  SER SER B . n 
B 2 372  VAL 372  387  387  VAL VAL B . n 
B 2 373  TRP 373  388  388  TRP TRP B . n 
B 2 374  PRO 374  389  389  PRO PRO B . n 
B 2 375  GLY 375  390  390  GLY GLY B . n 
B 2 376  TYR 376  391  391  TYR TYR B . n 
B 2 377  SER 377  392  392  SER SER B . n 
B 2 378  GLU 378  393  393  GLU GLU B . n 
B 2 379  THR 379  394  394  THR THR B . n 
B 2 380  VAL 380  395  395  VAL VAL B . n 
B 2 381  HIS 381  396  396  HIS HIS B . n 
B 2 382  SER 382  397  397  SER SER B . n 
B 2 383  SER 383  398  398  SER SER B . n 
B 2 384  LEU 384  399  399  LEU LEU B . n 
B 2 385  GLU 385  400  400  GLU GLU B . n 
B 2 386  GLN 386  401  401  GLN GLN B . n 
B 2 387  LEU 387  402  402  LEU LEU B . n 
B 2 388  HIS 388  403  403  HIS HIS B . n 
B 2 389  SER 389  404  404  SER SER B . n 
B 2 390  LYS 390  405  405  LYS LYS B . n 
B 2 391  TYR 391  406  406  TYR TYR B . n 
B 2 392  ASP 392  407  407  ASP ASP B . n 
B 2 393  GLU 393  408  408  GLU GLU B . n 
B 2 394  MET 394  409  409  MET MET B . n 
B 2 395  SER 395  410  410  SER SER B . n 
B 2 396  VAL 396  411  411  VAL VAL B . n 
B 2 397  LEU 397  412  412  LEU LEU B . n 
B 2 398  PHE 398  413  413  PHE PHE B . n 
B 2 399  SER 399  414  414  SER SER B . n 
B 2 400  VAL 400  415  415  VAL VAL B . n 
B 2 401  LEU 401  416  416  LEU LEU B . n 
B 2 402  VAL 402  417  417  VAL VAL B . n 
B 2 403  THR 403  418  418  THR THR B . n 
B 2 404  GLU 404  419  419  GLU GLU B . n 
B 2 405  THR 405  420  420  THR THR B . n 
B 2 406  THR 406  421  421  THR THR B . n 
B 2 407  LEU 407  422  422  LEU LEU B . n 
B 2 408  GLU 408  423  423  GLU GLU B . n 
B 2 409  ASN 409  424  424  ASN ASN B . n 
B 2 410  GLY 410  425  425  GLY GLY B . n 
B 2 411  LEU 411  426  426  LEU LEU B . n 
B 2 412  ILE 412  427  427  ILE ILE B . n 
B 2 413  GLN 413  428  428  GLN GLN B . n 
B 2 414  LEU 414  429  429  LEU LEU B . n 
B 2 415  ARG 415  430  430  ARG ARG B . n 
B 2 416  SER 416  431  431  SER SER B . n 
B 2 417  ARG 417  432  432  ARG ARG B . n 
B 2 418  ASP 418  433  433  ASP ASP B . n 
B 2 419  THR 419  434  434  THR THR B . n 
B 2 420  THR 420  435  435  THR THR B . n 
B 2 421  MET 421  436  436  MET MET B . n 
B 2 422  LYS 422  437  437  LYS LYS B . n 
B 2 423  GLU 423  438  438  GLU GLU B . n 
B 2 424  MET 424  439  439  MET MET B . n 
B 2 425  MET 425  440  440  MET MET B . n 
B 2 426  HIS 426  441  441  HIS HIS B . n 
B 2 427  ILE 427  442  442  ILE ILE B . n 
B 2 428  SER 428  443  443  SER SER B . n 
B 2 429  LYS 429  444  444  LYS LYS B . n 
B 2 430  LEU 430  445  445  LEU LEU B . n 
B 2 431  ARG 431  446  446  ARG ARG B . n 
B 2 432  ASP 432  447  447  ASP ASP B . n 
B 2 433  PHE 433  448  448  PHE PHE B . n 
B 2 434  LEU 434  449  449  LEU LEU B . n 
B 2 435  VAL 435  450  450  VAL VAL B . n 
B 2 436  LYS 436  451  451  LYS LYS B . n 
B 2 437  TYR 437  452  452  TYR TYR B . n 
B 2 438  LEU 438  453  453  LEU LEU B . n 
B 2 439  ALA 439  454  454  ALA ALA B . n 
B 2 440  SER 440  455  455  SER SER B . n 
B 2 441  ALA 441  456  456  ALA ALA B . n 
B 2 442  SER 442  457  457  SER SER B . n 
B 2 443  ASN 443  458  458  ASN ASN B . n 
B 2 444  VAL 444  459  ?    ?   ?   B . n 
B 2 445  HIS 445  460  ?    ?   ?   B . n 
B 2 446  HIS 446  461  ?    ?   ?   B . n 
B 2 447  HIS 447  462  ?    ?   ?   B . n 
B 2 448  HIS 448  463  ?    ?   ?   B . n 
B 2 449  HIS 449  464  ?    ?   ?   B . n 
B 2 450  HIS 450  465  ?    ?   ?   B . n 
C 2 1    MET 1    16   ?    ?   ?   C . n 
C 2 2    TRP 2    17   ?    ?   ?   C . n 
C 2 3    LEU 3    18   ?    ?   ?   C . n 
C 2 4    SER 4    19   ?    ?   ?   C . n 
C 2 5    GLY 5    20   ?    ?   ?   C . n 
C 2 6    TYR 6    21   ?    ?   ?   C . n 
C 2 7    ALA 7    22   ?    ?   ?   C . n 
C 2 8    GLY 8    23   ?    ?   ?   C . n 
C 2 9    PRO 9    24   ?    ?   ?   C . n 
C 2 10   ALA 10   25   ?    ?   ?   C . n 
C 2 11   ASP 11   26   ?    ?   ?   C . n 
C 2 12   GLY 12   27   ?    ?   ?   C . n 
C 2 13   THR 13   28   ?    ?   ?   C . n 
C 2 14   GLN 14   29   ?    ?   ?   C . n 
C 2 15   GLN 15   30   ?    ?   ?   C . n 
C 2 16   PRO 16   31   ?    ?   ?   C . n 
C 2 17   ASP 17   32   ?    ?   ?   C . n 
C 2 18   ALA 18   33   ?    ?   ?   C . n 
C 2 19   PRO 19   34   ?    ?   ?   C . n 
C 2 20   GLU 20   35   ?    ?   ?   C . n 
C 2 21   HIS 21   36   ?    ?   ?   C . n 
C 2 22   ALA 22   37   ?    ?   ?   C . n 
C 2 23   VAL 23   38   ?    ?   ?   C . n 
C 2 24   ALA 24   39   ?    ?   ?   C . n 
C 2 25   ARG 25   40   ?    ?   ?   C . n 
C 2 26   GLU 26   41   ?    ?   ?   C . n 
C 2 27   ALA 27   42   42   ALA ALA C . n 
C 2 28   LEU 28   43   43   LEU LEU C . n 
C 2 29   VAL 29   44   44   VAL VAL C . n 
C 2 30   ASP 30   45   45   ASP ASP C . n 
C 2 31   LEU 31   46   46   LEU LEU C . n 
C 2 32   CYS 32   47   47   CYS CYS C . n 
C 2 33   ARG 33   48   48   ARG ARG C . n 
C 2 34   ARG 34   49   49   ARG ARG C . n 
C 2 35   ARG 35   50   50   ARG ARG C . n 
C 2 36   HIS 36   51   51   HIS HIS C . n 
C 2 37   PHE 37   52   52   PHE PHE C . n 
C 2 38   PHE 38   53   53   PHE PHE C . n 
C 2 39   SER 39   54   54   SER SER C . n 
C 2 40   GLY 40   55   ?    ?   ?   C . n 
C 2 41   THR 41   56   ?    ?   ?   C . n 
C 2 42   PRO 42   57   ?    ?   ?   C . n 
C 2 43   GLN 43   58   ?    ?   ?   C . n 
C 2 44   GLN 44   59   ?    ?   ?   C . n 
C 2 45   LEU 45   60   ?    ?   ?   C . n 
C 2 46   SER 46   61   ?    ?   ?   C . n 
C 2 47   THR 47   62   ?    ?   ?   C . n 
C 2 48   ALA 48   63   ?    ?   ?   C . n 
C 2 49   ALA 49   64   ?    ?   ?   C . n 
C 2 50   LEU 50   65   ?    ?   ?   C . n 
C 2 51   LEU 51   66   ?    ?   ?   C . n 
C 2 52   SER 52   67   ?    ?   ?   C . n 
C 2 53   GLY 53   68   ?    ?   ?   C . n 
C 2 54   CYS 54   69   ?    ?   ?   C . n 
C 2 55   HIS 55   70   ?    ?   ?   C . n 
C 2 56   ALA 56   71   ?    ?   ?   C . n 
C 2 57   ARG 57   72   72   ARG ARG C . n 
C 2 58   PHE 58   73   73   PHE PHE C . n 
C 2 59   GLY 59   74   74   GLY GLY C . n 
C 2 60   PRO 60   75   75   PRO PRO C . n 
C 2 61   LEU 61   76   76   LEU LEU C . n 
C 2 62   GLY 62   77   77   GLY GLY C . n 
C 2 63   VAL 63   78   78   VAL VAL C . n 
C 2 64   GLU 64   79   79   GLU GLU C . n 
C 2 65   LEU 65   80   80   LEU LEU C . n 
C 2 66   ARG 66   81   81   ARG ARG C . n 
C 2 67   LYS 67   82   82   LYS LYS C . n 
C 2 68   ASN 68   83   83   ASN ASN C . n 
C 2 69   LEU 69   84   84   LEU LEU C . n 
C 2 70   ALA 70   85   85   ALA ALA C . n 
C 2 71   SER 71   86   86   SER SER C . n 
C 2 72   GLN 72   87   87   GLN GLN C . n 
C 2 73   TRP 73   88   88   TRP TRP C . n 
C 2 74   TRP 74   89   89   TRP TRP C . n 
C 2 75   SER 75   90   90   SER SER C . n 
C 2 76   SER 76   91   91   SER SER C . n 
C 2 77   MET 77   92   92   MET MET C . n 
C 2 78   VAL 78   93   93   VAL VAL C . n 
C 2 79   VAL 79   94   94   VAL VAL C . n 
C 2 80   PHE 80   95   95   PHE PHE C . n 
C 2 81   ARG 81   96   96   ARG ARG C . n 
C 2 82   GLU 82   97   97   GLU GLU C . n 
C 2 83   GLN 83   98   98   GLN GLN C . n 
C 2 84   VAL 84   99   99   VAL VAL C . n 
C 2 85   PHE 85   100  100  PHE PHE C . n 
C 2 86   ALA 86   101  101  ALA ALA C . n 
C 2 87   VAL 87   102  102  VAL VAL C . n 
C 2 88   ASP 88   103  103  ASP ASP C . n 
C 2 89   SER 89   104  104  SER SER C . n 
C 2 90   LEU 90   105  105  LEU LEU C . n 
C 2 91   HIS 91   106  106  HIS HIS C . n 
C 2 92   GLN 92   107  107  GLN GLN C . n 
C 2 93   GLU 93   108  108  GLU GLU C . n 
C 2 94   PRO 94   109  109  PRO PRO C . n 
C 2 95   GLY 95   110  110  GLY GLY C . n 
C 2 96   SER 96   111  111  SER SER C . n 
C 2 97   SER 97   112  112  SER SER C . n 
C 2 98   GLN 98   113  113  GLN GLN C . n 
C 2 99   PRO 99   114  114  PRO PRO C . n 
C 2 100  ARG 100  115  115  ARG ARG C . n 
C 2 101  ASP 101  116  116  ASP ASP C . n 
C 2 102  SER 102  117  117  SER SER C . n 
C 2 103  ALA 103  118  118  ALA ALA C . n 
C 2 104  PHE 104  119  119  PHE PHE C . n 
C 2 105  ARG 105  120  120  ARG ARG C . n 
C 2 106  LEU 106  121  121  LEU LEU C . n 
C 2 107  VAL 107  122  122  VAL VAL C . n 
C 2 108  SER 108  123  123  SER SER C . n 
C 2 109  PRO 109  124  124  PRO PRO C . n 
C 2 110  GLU 110  125  125  GLU GLU C . n 
C 2 111  SER 111  126  126  SER SER C . n 
C 2 112  ILE 112  127  ?    ?   ?   C . n 
C 2 113  ARG 113  128  ?    ?   ?   C . n 
C 2 114  GLU 114  129  ?    ?   ?   C . n 
C 2 115  ILE 115  130  ?    ?   ?   C . n 
C 2 116  LEU 116  131  ?    ?   ?   C . n 
C 2 117  GLN 117  132  ?    ?   ?   C . n 
C 2 118  ASP 118  133  ?    ?   ?   C . n 
C 2 119  ARG 119  134  ?    ?   ?   C . n 
C 2 120  GLU 120  135  ?    ?   ?   C . n 
C 2 121  PRO 121  136  ?    ?   ?   C . n 
C 2 122  SER 122  137  ?    ?   ?   C . n 
C 2 123  LYS 123  138  ?    ?   ?   C . n 
C 2 124  GLU 124  139  ?    ?   ?   C . n 
C 2 125  GLN 125  140  ?    ?   ?   C . n 
C 2 126  LEU 126  141  ?    ?   ?   C . n 
C 2 127  VAL 127  142  ?    ?   ?   C . n 
C 2 128  ALA 128  143  ?    ?   ?   C . n 
C 2 129  PHE 129  144  ?    ?   ?   C . n 
C 2 130  LEU 130  145  145  LEU LEU C . n 
C 2 131  GLU 131  146  146  GLU GLU C . n 
C 2 132  ASN 132  147  147  ASN ASN C . n 
C 2 133  LEU 133  148  148  LEU LEU C . n 
C 2 134  LEU 134  149  149  LEU LEU C . n 
C 2 135  LYS 135  150  150  LYS LYS C . n 
C 2 136  THR 136  151  151  THR THR C . n 
C 2 137  SER 137  152  152  SER SER C . n 
C 2 138  GLY 138  153  153  GLY GLY C . n 
C 2 139  LYS 139  154  154  LYS LYS C . n 
C 2 140  LEU 140  155  155  LEU LEU C . n 
C 2 141  ARG 141  156  156  ARG ARG C . n 
C 2 142  ALA 142  157  157  ALA ALA C . n 
C 2 143  THR 143  158  158  THR THR C . n 
C 2 144  LEU 144  159  159  LEU LEU C . n 
C 2 145  LEU 145  160  160  LEU LEU C . n 
C 2 146  HIS 146  161  161  HIS HIS C . n 
C 2 147  GLY 147  162  162  GLY GLY C . n 
C 2 148  ALA 148  163  163  ALA ALA C . n 
C 2 149  LEU 149  164  164  LEU LEU C . n 
C 2 150  GLU 150  165  165  GLU GLU C . n 
C 2 151  HIS 151  166  166  HIS HIS C . n 
C 2 152  TYR 152  167  167  TYR TYR C . n 
C 2 153  VAL 153  168  168  VAL VAL C . n 
C 2 154  ASN 154  169  169  ASN ASN C . n 
C 2 155  CYS 155  170  170  CYS CYS C . n 
C 2 156  LEU 156  171  171  LEU LEU C . n 
C 2 157  ASP 157  172  172  ASP ASP C . n 
C 2 158  LEU 158  173  173  LEU LEU C . n 
C 2 159  VAL 159  174  174  VAL VAL C . n 
C 2 160  ASN 160  175  175  ASN ASN C . n 
C 2 161  ARG 161  176  176  ARG ARG C . n 
C 2 162  LYS 162  177  177  LYS LYS C . n 
C 2 163  LEU 163  178  178  LEU LEU C . n 
C 2 164  PRO 164  179  179  PRO PRO C . n 
C 2 165  PHE 165  180  180  PHE PHE C . n 
C 2 166  GLY 166  181  181  GLY GLY C . n 
C 2 167  LEU 167  182  182  LEU LEU C . n 
C 2 168  ALA 168  183  183  ALA ALA C . n 
C 2 169  GLN 169  184  184  GLN GLN C . n 
C 2 170  ILE 170  185  185  ILE ILE C . n 
C 2 171  GLY 171  186  186  GLY GLY C . n 
C 2 172  VAL 172  187  187  VAL VAL C . n 
C 2 173  CYS 173  188  188  CYS CYS C . n 
C 2 174  PHE 174  189  189  PHE PHE C . n 
C 2 175  HIS 175  190  190  HIS HIS C . n 
C 2 176  PRO 176  191  191  PRO PRO C . n 
C 2 177  VAL 177  192  192  VAL VAL C . n 
C 2 178  SER 178  193  ?    ?   ?   C . n 
C 2 179  ASN 179  194  ?    ?   ?   C . n 
C 2 180  SER 180  195  ?    ?   ?   C . n 
C 2 181  ASN 181  196  ?    ?   ?   C . n 
C 2 182  GLN 182  197  ?    ?   ?   C . n 
C 2 183  THR 183  198  ?    ?   ?   C . n 
C 2 184  PRO 184  199  ?    ?   ?   C . n 
C 2 185  SER 185  200  ?    ?   ?   C . n 
C 2 186  SER 186  201  ?    ?   ?   C . n 
C 2 187  VAL 187  202  ?    ?   ?   C . n 
C 2 188  THR 188  203  ?    ?   ?   C . n 
C 2 189  ARG 189  204  204  ARG ARG C . n 
C 2 190  VAL 190  205  205  VAL VAL C . n 
C 2 191  GLY 191  206  206  GLY GLY C . n 
C 2 192  GLU 192  207  207  GLU GLU C . n 
C 2 193  LYS 193  208  208  LYS LYS C . n 
C 2 194  THR 194  209  209  THR THR C . n 
C 2 195  GLU 195  210  210  GLU GLU C . n 
C 2 196  ALA 196  211  211  ALA ALA C . n 
C 2 197  SER 197  212  212  SER SER C . n 
C 2 198  LEU 198  213  213  LEU LEU C . n 
C 2 199  VAL 199  214  214  VAL VAL C . n 
C 2 200  TRP 200  215  215  TRP TRP C . n 
C 2 201  PHE 201  216  216  PHE PHE C . n 
C 2 202  THR 202  217  217  THR THR C . n 
C 2 203  PRO 203  218  218  PRO PRO C . n 
C 2 204  THR 204  219  219  THR THR C . n 
C 2 205  ARG 205  220  220  ARG ARG C . n 
C 2 206  THR 206  221  221  THR THR C . n 
C 2 207  SER 207  222  222  SER SER C . n 
C 2 208  SER 208  223  223  SER SER C . n 
C 2 209  GLN 209  224  224  GLN GLN C . n 
C 2 210  TRP 210  225  225  TRP TRP C . n 
C 2 211  LEU 211  226  226  LEU LEU C . n 
C 2 212  ASP 212  227  227  ASP ASP C . n 
C 2 213  PHE 213  228  228  PHE PHE C . n 
C 2 214  TRP 214  229  229  TRP TRP C . n 
C 2 215  LEU 215  230  230  LEU LEU C . n 
C 2 216  ARG 216  231  231  ARG ARG C . n 
C 2 217  HIS 217  232  232  HIS HIS C . n 
C 2 218  ARG 218  233  233  ARG ARG C . n 
C 2 219  LEU 219  234  234  LEU LEU C . n 
C 2 220  LEU 220  235  235  LEU LEU C . n 
C 2 221  TRP 221  236  236  TRP TRP C . n 
C 2 222  TRP 222  237  237  TRP TRP C . n 
C 2 223  ARG 223  238  238  ARG ARG C . n 
C 2 224  LYS 224  239  239  LYS LYS C . n 
C 2 225  PHE 225  240  240  PHE PHE C . n 
C 2 226  ALA 226  241  241  ALA ALA C . n 
C 2 227  MET 227  242  242  MET MET C . n 
C 2 228  SER 228  243  243  SER SER C . n 
C 2 229  PRO 229  244  244  PRO PRO C . n 
C 2 230  SER 230  245  245  SER SER C . n 
C 2 231  ASN 231  246  246  ASN ASN C . n 
C 2 232  PHE 232  247  247  PHE PHE C . n 
C 2 233  SER 233  248  248  SER SER C . n 
C 2 234  SER 234  249  249  SER SER C . n 
C 2 235  ALA 235  250  250  ALA ALA C . n 
C 2 236  ASP 236  251  251  ASP ASP C . n 
C 2 237  CYS 237  252  252  CYS CYS C . n 
C 2 238  GLN 238  253  253  GLN GLN C . n 
C 2 239  ASP 239  254  254  ASP ASP C . n 
C 2 240  GLU 240  255  255  GLU GLU C . n 
C 2 241  LEU 241  256  256  LEU LEU C . n 
C 2 242  GLY 242  257  257  GLY GLY C . n 
C 2 243  ARG 243  258  258  ARG ARG C . n 
C 2 244  LYS 244  259  259  LYS LYS C . n 
C 2 245  GLY 245  260  260  GLY GLY C . n 
C 2 246  SER 246  261  261  SER SER C . n 
C 2 247  LYS 247  262  262  LYS LYS C . n 
C 2 248  LEU 248  263  263  LEU LEU C . n 
C 2 249  TYR 249  264  264  TYR TYR C . n 
C 2 250  TYR 250  265  265  TYR TYR C . n 
C 2 251  SER 251  266  266  SER SER C . n 
C 2 252  PHE 252  267  267  PHE PHE C . n 
C 2 253  PRO 253  268  268  PRO PRO C . n 
C 2 254  TRP 254  269  269  TRP TRP C . n 
C 2 255  GLY 255  270  270  GLY GLY C . n 
C 2 256  LYS 256  271  271  LYS LYS C . n 
C 2 257  GLU 257  272  272  GLU GLU C . n 
C 2 258  PRO 258  273  273  PRO PRO C . n 
C 2 259  ILE 259  274  274  ILE ILE C . n 
C 2 260  GLU 260  275  275  GLU GLU C . n 
C 2 261  THR 261  276  276  THR THR C . n 
C 2 262  LEU 262  277  277  LEU LEU C . n 
C 2 263  TRP 263  278  278  TRP TRP C . n 
C 2 264  ASN 264  279  279  ASN ASN C . n 
C 2 265  LEU 265  280  280  LEU LEU C . n 
C 2 266  GLY 266  281  281  GLY GLY C . n 
C 2 267  ASP 267  282  282  ASP ASP C . n 
C 2 268  GLN 268  283  283  GLN GLN C . n 
C 2 269  GLU 269  284  284  GLU GLU C . n 
C 2 270  LEU 270  285  285  LEU LEU C . n 
C 2 271  LEU 271  286  286  LEU LEU C . n 
C 2 272  HIS 272  287  287  HIS HIS C . n 
C 2 273  THR 273  288  288  THR THR C . n 
C 2 274  TYR 274  289  289  TYR TYR C . n 
C 2 275  PRO 275  290  290  PRO PRO C . n 
C 2 276  GLY 276  291  291  GLY GLY C . n 
C 2 277  ASN 277  292  292  ASN ASN C . n 
C 2 278  VAL 278  293  293  VAL VAL C . n 
C 2 279  SER 279  294  294  SER SER C . n 
C 2 280  THR 280  295  295  THR THR C . n 
C 2 281  ILE 281  296  296  ILE ILE C . n 
C 2 282  GLN 282  297  ?    ?   ?   C . n 
C 2 283  GLY 283  298  ?    ?   ?   C . n 
C 2 284  ARG 284  299  ?    ?   ?   C . n 
C 2 285  ASP 285  300  300  ASP ASP C . n 
C 2 286  GLY 286  301  301  GLY GLY C . n 
C 2 287  ARG 287  302  302  ARG ARG C . n 
C 2 288  LYS 288  303  303  LYS LYS C . n 
C 2 289  ASN 289  304  304  ASN ASN C . n 
C 2 290  VAL 290  305  305  VAL VAL C . n 
C 2 291  VAL 291  306  306  VAL VAL C . n 
C 2 292  PRO 292  307  307  PRO PRO C . n 
C 2 293  CYS 293  308  308  CYS CYS C . n 
C 2 294  VAL 294  309  309  VAL VAL C . n 
C 2 295  LEU 295  310  310  LEU LEU C . n 
C 2 296  SER 296  311  311  SER SER C . n 
C 2 297  VAL 297  312  312  VAL VAL C . n 
C 2 298  SER 298  313  313  SER SER C . n 
C 2 299  GLY 299  314  314  GLY GLY C . n 
C 2 300  ASP 300  315  315  ASP ASP C . n 
C 2 301  VAL 301  316  316  VAL VAL C . n 
C 2 302  ASP 302  317  317  ASP ASP C . n 
C 2 303  LEU 303  318  318  LEU LEU C . n 
C 2 304  GLY 304  319  319  GLY GLY C . n 
C 2 305  THR 305  320  320  THR THR C . n 
C 2 306  LEU 306  321  321  LEU LEU C . n 
C 2 307  ALA 307  322  322  ALA ALA C . n 
C 2 308  TYR 308  323  323  TYR TYR C . n 
C 2 309  LEU 309  324  324  LEU LEU C . n 
C 2 310  TYR 310  325  325  TYR TYR C . n 
C 2 311  ASP 311  326  326  ASP ASP C . n 
C 2 312  SER 312  327  327  SER SER C . n 
C 2 313  PHE 313  328  328  PHE PHE C . n 
C 2 314  GLN 314  329  ?    ?   ?   C . n 
C 2 315  LEU 315  330  ?    ?   ?   C . n 
C 2 316  ALA 316  331  ?    ?   ?   C . n 
C 2 317  GLU 317  332  ?    ?   ?   C . n 
C 2 318  ASN 318  333  ?    ?   ?   C . n 
C 2 319  SER 319  334  ?    ?   ?   C . n 
C 2 320  PHE 320  335  ?    ?   ?   C . n 
C 2 321  ALA 321  336  ?    ?   ?   C . n 
C 2 322  ARG 322  337  ?    ?   ?   C . n 
C 2 323  LYS 323  338  ?    ?   ?   C . n 
C 2 324  LYS 324  339  ?    ?   ?   C . n 
C 2 325  SER 325  340  ?    ?   ?   C . n 
C 2 326  LEU 326  341  ?    ?   ?   C . n 
C 2 327  GLN 327  342  ?    ?   ?   C . n 
C 2 328  ARG 328  343  ?    ?   ?   C . n 
C 2 329  LYS 329  344  ?    ?   ?   C . n 
C 2 330  VAL 330  345  345  VAL VAL C . n 
C 2 331  LEU 331  346  346  LEU LEU C . n 
C 2 332  LYS 332  347  347  LYS LYS C . n 
C 2 333  LEU 333  348  348  LEU LEU C . n 
C 2 334  HIS 334  349  349  HIS HIS C . n 
C 2 335  PRO 335  350  350  PRO PRO C . n 
C 2 336  CYS 336  351  351  CYS CYS C . n 
C 2 337  LEU 337  352  352  LEU LEU C . n 
C 2 338  ALA 338  353  353  ALA ALA C . n 
C 2 339  PRO 339  354  354  PRO PRO C . n 
C 2 340  ILE 340  355  355  ILE ILE C . n 
C 2 341  LYS 341  356  356  LYS LYS C . n 
C 2 342  VAL 342  357  357  VAL VAL C . n 
C 2 343  ALA 343  358  358  ALA ALA C . n 
C 2 344  LEU 344  359  359  LEU LEU C . n 
C 2 345  ASP 345  360  360  ASP ASP C . n 
C 2 346  VAL 346  361  361  VAL VAL C . n 
C 2 347  GLY 347  362  362  GLY GLY C . n 
C 2 348  LYS 348  363  363  LYS LYS C . n 
C 2 349  GLY 349  364  ?    ?   ?   C . n 
C 2 350  PRO 350  365  ?    ?   ?   C . n 
C 2 351  THR 351  366  366  THR THR C . n 
C 2 352  VAL 352  367  367  VAL VAL C . n 
C 2 353  GLU 353  368  368  GLU GLU C . n 
C 2 354  LEU 354  369  369  LEU LEU C . n 
C 2 355  ARG 355  370  370  ARG ARG C . n 
C 2 356  GLN 356  371  371  GLN GLN C . n 
C 2 357  VAL 357  372  372  VAL VAL C . n 
C 2 358  CYS 358  373  373  CYS CYS C . n 
C 2 359  GLN 359  374  374  GLN GLN C . n 
C 2 360  GLY 360  375  375  GLY GLY C . n 
C 2 361  LEU 361  376  376  LEU LEU C . n 
C 2 362  LEU 362  377  377  LEU LEU C . n 
C 2 363  ASN 363  378  378  ASN ASN C . n 
C 2 364  GLU 364  379  379  GLU GLU C . n 
C 2 365  LEU 365  380  380  LEU LEU C . n 
C 2 366  LEU 366  381  381  LEU LEU C . n 
C 2 367  GLU 367  382  382  GLU GLU C . n 
C 2 368  ASN 368  383  383  ASN ASN C . n 
C 2 369  GLY 369  384  384  GLY GLY C . n 
C 2 370  ILE 370  385  385  ILE ILE C . n 
C 2 371  SER 371  386  386  SER SER C . n 
C 2 372  VAL 372  387  387  VAL VAL C . n 
C 2 373  TRP 373  388  388  TRP TRP C . n 
C 2 374  PRO 374  389  389  PRO PRO C . n 
C 2 375  GLY 375  390  390  GLY GLY C . n 
C 2 376  TYR 376  391  391  TYR TYR C . n 
C 2 377  SER 377  392  392  SER SER C . n 
C 2 378  GLU 378  393  393  GLU GLU C . n 
C 2 379  THR 379  394  394  THR THR C . n 
C 2 380  VAL 380  395  395  VAL VAL C . n 
C 2 381  HIS 381  396  ?    ?   ?   C . n 
C 2 382  SER 382  397  ?    ?   ?   C . n 
C 2 383  SER 383  398  398  SER SER C . n 
C 2 384  LEU 384  399  399  LEU LEU C . n 
C 2 385  GLU 385  400  400  GLU GLU C . n 
C 2 386  GLN 386  401  401  GLN GLN C . n 
C 2 387  LEU 387  402  402  LEU LEU C . n 
C 2 388  HIS 388  403  403  HIS HIS C . n 
C 2 389  SER 389  404  404  SER SER C . n 
C 2 390  LYS 390  405  405  LYS LYS C . n 
C 2 391  TYR 391  406  406  TYR TYR C . n 
C 2 392  ASP 392  407  407  ASP ASP C . n 
C 2 393  GLU 393  408  408  GLU GLU C . n 
C 2 394  MET 394  409  409  MET MET C . n 
C 2 395  SER 395  410  410  SER SER C . n 
C 2 396  VAL 396  411  411  VAL VAL C . n 
C 2 397  LEU 397  412  412  LEU LEU C . n 
C 2 398  PHE 398  413  413  PHE PHE C . n 
C 2 399  SER 399  414  414  SER SER C . n 
C 2 400  VAL 400  415  415  VAL VAL C . n 
C 2 401  LEU 401  416  416  LEU LEU C . n 
C 2 402  VAL 402  417  417  VAL VAL C . n 
C 2 403  THR 403  418  418  THR THR C . n 
C 2 404  GLU 404  419  419  GLU GLU C . n 
C 2 405  THR 405  420  420  THR THR C . n 
C 2 406  THR 406  421  421  THR THR C . n 
C 2 407  LEU 407  422  422  LEU LEU C . n 
C 2 408  GLU 408  423  423  GLU GLU C . n 
C 2 409  ASN 409  424  424  ASN ASN C . n 
C 2 410  GLY 410  425  425  GLY GLY C . n 
C 2 411  LEU 411  426  426  LEU LEU C . n 
C 2 412  ILE 412  427  427  ILE ILE C . n 
C 2 413  GLN 413  428  428  GLN GLN C . n 
C 2 414  LEU 414  429  429  LEU LEU C . n 
C 2 415  ARG 415  430  430  ARG ARG C . n 
C 2 416  SER 416  431  431  SER SER C . n 
C 2 417  ARG 417  432  432  ARG ARG C . n 
C 2 418  ASP 418  433  433  ASP ASP C . n 
C 2 419  THR 419  434  434  THR THR C . n 
C 2 420  THR 420  435  435  THR THR C . n 
C 2 421  MET 421  436  436  MET MET C . n 
C 2 422  LYS 422  437  437  LYS LYS C . n 
C 2 423  GLU 423  438  438  GLU GLU C . n 
C 2 424  MET 424  439  439  MET MET C . n 
C 2 425  MET 425  440  440  MET MET C . n 
C 2 426  HIS 426  441  441  HIS HIS C . n 
C 2 427  ILE 427  442  442  ILE ILE C . n 
C 2 428  SER 428  443  443  SER SER C . n 
C 2 429  LYS 429  444  444  LYS LYS C . n 
C 2 430  LEU 430  445  445  LEU LEU C . n 
C 2 431  ARG 431  446  446  ARG ARG C . n 
C 2 432  ASP 432  447  447  ASP ASP C . n 
C 2 433  PHE 433  448  448  PHE PHE C . n 
C 2 434  LEU 434  449  449  LEU LEU C . n 
C 2 435  VAL 435  450  450  VAL VAL C . n 
C 2 436  LYS 436  451  451  LYS LYS C . n 
C 2 437  TYR 437  452  452  TYR TYR C . n 
C 2 438  LEU 438  453  453  LEU LEU C . n 
C 2 439  ALA 439  454  454  ALA ALA C . n 
C 2 440  SER 440  455  455  SER SER C . n 
C 2 441  ALA 441  456  456  ALA ALA C . n 
C 2 442  SER 442  457  457  SER SER C . n 
C 2 443  ASN 443  458  ?    ?   ?   C . n 
C 2 444  VAL 444  459  ?    ?   ?   C . n 
C 2 445  HIS 445  460  ?    ?   ?   C . n 
C 2 446  HIS 446  461  ?    ?   ?   C . n 
C 2 447  HIS 447  462  ?    ?   ?   C . n 
C 2 448  HIS 448  463  ?    ?   ?   C . n 
C 2 449  HIS 449  464  ?    ?   ?   C . n 
C 2 450  HIS 450  465  ?    ?   ?   C . n 
D 3 1    DG  1    1    ?    ?   ?   P . n 
D 3 2    DC  2    2    ?    ?   ?   P . n 
D 3 3    DA  3    3    ?    ?   ?   P . n 
D 3 4    DT  4    4    ?    ?   ?   P . n 
D 3 5    DG  5    5    5    DG  DG  P . n 
D 3 6    DC  6    6    6    DC  DC  P . n 
D 3 7    DG  7    7    7    DG  DG  P . n 
D 3 8    DG  8    8    8    DG  DG  P . n 
D 3 9    DT  9    9    9    DT  DT  P . n 
D 3 10   DC  10   10   10   DC  DC  P . n 
D 3 11   DG  11   11   11   DG  DG  P . n 
D 3 12   DA  12   12   12   DA  DA  P . n 
D 3 13   DG  13   13   13   DG  DG  P . n 
D 3 14   DT  14   14   14   DT  DT  P . n 
D 3 15   DC  15   15   15   DC  DC  P . n 
D 3 16   DT  16   16   16   DT  DT  P . n 
D 3 17   DA  17   17   17   DA  DA  P . n 
D 3 18   DG  18   18   18   DG  DG  P . n 
D 3 19   DA  19   19   19   DA  DA  P . n 
D 3 20   DG  20   20   20   DG  DG  P . n 
D 3 21   DG  21   21   21   DG  DG  P . n 
D 3 22   DA  22   22   22   DA  DA  P . n 
D 3 23   DG  23   23   23   DG  DG  P . n 
D 3 24   DC  24   24   24   DC  DC  P . n 
D 3 25   DT  25   25   25   DT  DT  P . n 
E 4 1    DT  1    1    ?    ?   ?   T . n 
E 4 2    DT  2    2    ?    ?   ?   T . n 
E 4 3    DT  3    3    ?    ?   ?   T . n 
E 4 4    DT  4    4    ?    ?   ?   T . n 
E 4 5    DT  5    5    ?    ?   ?   T . n 
E 4 6    DT  6    6    ?    ?   ?   T . n 
E 4 7    DT  7    7    ?    ?   ?   T . n 
E 4 8    DT  8    8    ?    ?   ?   T . n 
E 4 9    DT  9    9    ?    ?   ?   T . n 
E 4 10   DT  10   10   ?    ?   ?   T . n 
E 4 11   DA  11   11   ?    ?   ?   T . n 
E 4 12   DT  12   12   ?    ?   ?   T . n 
E 4 13   DC  13   13   ?    ?   ?   T . n 
E 4 14   DC  14   14   ?    ?   ?   T . n 
E 4 15   DG  15   15   ?    ?   ?   T . n 
E 4 16   DG  16   16   ?    ?   ?   T . n 
E 4 17   DG  17   17   17   DG  DG  T . n 
E 4 18   DC  18   18   18   DC  DC  T . n 
E 4 19   DT  19   19   19   DT  DT  T . n 
E 4 20   DC  20   20   20   DC  DC  T . n 
E 4 21   DC  21   21   21   DC  DC  T . n 
E 4 22   DT  22   22   22   DT  DT  T . n 
E 4 23   DC  23   23   23   DC  DC  T . n 
E 4 24   DT  24   24   24   DT  DT  T . n 
E 4 25   DA  25   25   25   DA  DA  T . n 
E 4 26   DG  26   26   26   DG  DG  T . n 
E 4 27   DA  27   27   27   DA  DA  T . n 
E 4 28   DC  28   28   28   DC  DC  T . n 
E 4 29   DT  29   29   29   DT  DT  T . n 
E 4 30   DC  30   30   30   DC  DC  T . n 
E 4 31   DG  31   31   31   DG  DG  T . n 
E 4 32   DA  32   32   32   DA  DA  T . n 
E 4 33   DC  33   33   33   DC  DC  T . n 
E 4 34   DC  34   34   34   DC  DC  T . n 
E 4 35   DG  35   35   35   DG  DG  T . n 
E 4 36   DC  36   36   36   DC  DC  T . n 
E 4 37   DA  37   37   ?    ?   ?   T . n 
E 4 38   DT  38   38   ?    ?   ?   T . n 
E 4 39   DG  39   39   ?    ?   ?   T . n 
E 4 40   DC  40   40   ?    ?   ?   T . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 CA  ? ? CA  ? ? 'SUBJECT OF INVESTIGATION' ? 
2 DCP ? ? DCP ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
F 5 CA  1 1301 1301 CA  CA  A . 
G 5 CA  1 1302 1302 CA  CA  A . 
H 5 CA  1 1303 1303 CA  CA  A . 
I 6 DCP 1 1304 1304 DCP DCP A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LYS 990 ? CG  ? A LYS 972 CG  
2  1 Y 1 A LYS 990 ? CD  ? A LYS 972 CD  
3  1 Y 1 A LYS 990 ? CE  ? A LYS 972 CE  
4  1 Y 1 A LYS 990 ? NZ  ? A LYS 972 NZ  
5  1 Y 1 C ARG 115 ? CG  ? C ARG 100 CG  
6  1 Y 1 C ARG 115 ? CD  ? C ARG 100 CD  
7  1 Y 1 C ARG 115 ? NE  ? C ARG 100 NE  
8  1 Y 1 C ARG 115 ? CZ  ? C ARG 100 CZ  
9  1 Y 1 C ARG 115 ? NH1 ? C ARG 100 NH1 
10 1 Y 1 C ARG 115 ? NH2 ? C ARG 100 NH2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9IC3 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9IC3 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9IC3 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9IC3 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.96 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.correlation_coeff_I_to_Fcsqd_work        ? 
_refine.correlation_coeff_I_to_Fcsqd_free        ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'REAL-SPACE (WEIGHTED MAP SUM AT ATOM CENTERS)' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_struct.entry_id                     9IC3 
_struct.title                        
'Chimeric mitochondrial DNA polymerase gamma ternary complex (hAmB) in mouse-like error-editing conformer (composite)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9IC3 
_struct_keywords.text            'Mitochondrial DNA polymerase, TRANSFERASE' 
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
F N N 5 ? 
G N N 5 ? 
H N N 5 ? 
I N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP DPOG1_HUMAN P54098 ? 1 
;VSSSVPASDPSDGQRRRQQQQQQQQQQQQQPQQPQVLSSEGGQLRHNPLDIQMLSRGLHEQIFGQGGEMPGEAAVRRSVE
HLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAV
PVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQRDWQEQL
VVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARRGPAISSW
DWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLA
GMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKK
EPATASKLPIEGAGAPGDPMDQEDLGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAW
TPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPGRRDNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEQGK
QQLMPQEAGLAEEFLLTDNSAIWQTVEELDYLEVEAEAKMENLRAAVPGQPLALTARGGPKDTQPSYHHGNGPYNDVDIP
GCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAV
IRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDA
HFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQM
YAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIA
TSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREED
RYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIE
LTKGSLEKRSQPGP
;
26 
2 UNP DPOG2_MOUSE Q9QZM2 ? 2 
;WLSGYAGPADGTQQPDAPEHAVAREALVDLCRRRHFFSGTPQQLSTAALLSGCHARFGPLGVELRKNLASQWWSSMVVFR
EQVFAVDSLHQEPGSSQPRDSAFRLVSPESIREILQDREPSKEQLVAFLENLLKTSGKLRATLLHGALEHYVNCLDLVNR
KLPFGLAQIGVCFHPVSNSNQTPSSVTRVGEKTEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAMSPSNFSSADCQDEL
GRKGSKLYYSFPWGKEPIETLWNLGDQELLHTYPGNVSTIQGRDGRKNVVPCVLSVSGDVDLGTLAYLYDSFQLAENSFA
RKKSLQRKVLKLHPCLAPIKVALDVGKGPTVELRQVCQGLLNELLENGISVWPGYSETVHSSLEQLHSKYDEMSVLFSVL
VTETTLENGLIQLRSRDTTMKEMMHISKLRDFLVKYLASASNV
;
17 
3 PDB 9IC3        9IC3   ? 3 ? 1  
4 PDB 9IC3        9IC3   ? 4 ? 1  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9IC3 A 8 ? 1221 ? P54098 26 ? 1239 ? 26 1239 
2 2 9IC3 B 2 ? 444  ? Q9QZM2 17 ? 459  ? 17 459  
3 2 9IC3 C 2 ? 444  ? Q9QZM2 17 ? 459  ? 17 459  
4 3 9IC3 P 1 ? 25   ? 9IC3   1  ? 25   ? 1  25   
5 4 9IC3 T 1 ? 40   ? 9IC3   1  ? 40   ? 1  40   
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9IC3 MET A 1   ? UNP P54098 ? ? 'initiating methionine' 19  1  
1 9IC3 HIS A 2   ? UNP P54098 ? ? 'expression tag'        20  2  
1 9IC3 HIS A 3   ? UNP P54098 ? ? 'expression tag'        21  3  
1 9IC3 HIS A 4   ? UNP P54098 ? ? 'expression tag'        22  4  
1 9IC3 HIS A 5   ? UNP P54098 ? ? 'expression tag'        23  5  
1 9IC3 HIS A 6   ? UNP P54098 ? ? 'expression tag'        24  6  
1 9IC3 HIS A 7   ? UNP P54098 ? ? 'expression tag'        25  7  
2 9IC3 MET B 1   ? UNP Q9QZM2 ? ? 'initiating methionine' 16  8  
2 9IC3 HIS B 445 ? UNP Q9QZM2 ? ? 'expression tag'        460 9  
2 9IC3 HIS B 446 ? UNP Q9QZM2 ? ? 'expression tag'        461 10 
2 9IC3 HIS B 447 ? UNP Q9QZM2 ? ? 'expression tag'        462 11 
2 9IC3 HIS B 448 ? UNP Q9QZM2 ? ? 'expression tag'        463 12 
2 9IC3 HIS B 449 ? UNP Q9QZM2 ? ? 'expression tag'        464 13 
2 9IC3 HIS B 450 ? UNP Q9QZM2 ? ? 'expression tag'        465 14 
3 9IC3 MET C 1   ? UNP Q9QZM2 ? ? 'initiating methionine' 16  15 
3 9IC3 HIS C 445 ? UNP Q9QZM2 ? ? 'expression tag'        460 16 
3 9IC3 HIS C 446 ? UNP Q9QZM2 ? ? 'expression tag'        461 17 
3 9IC3 HIS C 447 ? UNP Q9QZM2 ? ? 'expression tag'        462 18 
3 9IC3 HIS C 448 ? UNP Q9QZM2 ? ? 'expression tag'        463 19 
3 9IC3 HIS C 449 ? UNP Q9QZM2 ? ? 'expression tag'        464 20 
3 9IC3 HIS C 450 ? UNP Q9QZM2 ? ? 'expression tag'        465 21 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 62   ? GLU A 67   ? SER A 80   GLU A 85   1 ? 6  
HELX_P HELX_P2  AA2 GLY A 78   ? HIS A 92   ? GLY A 96   HIS A 110  1 ? 15 
HELX_P HELX_P3  AA3 ASN A 116  ? SER A 129  ? ASN A 134  SER A 147  1 ? 14 
HELX_P HELX_P4  AA4 SER A 129  ? GLN A 141  ? SER A 147  GLN A 159  1 ? 13 
HELX_P HELX_P5  AA5 SER A 207  ? GLU A 212  ? SER A 225  GLU A 230  1 ? 6  
HELX_P HELX_P6  AA6 SER A 222  ? LEU A 226  ? SER A 240  LEU A 244  5 ? 5  
HELX_P HELX_P7  AA7 ASN A 252  ? ALA A 258  ? ASN A 270  ALA A 276  1 ? 7  
HELX_P HELX_P8  AA8 THR A 276  ? GLY A 285  ? THR A 294  GLY A 303  1 ? 10 
HELX_P HELX_P9  AA9 SER A 287  ? ILE A 295  ? SER A 305  ILE A 313  1 ? 9  
HELX_P HELX_P10 AB1 SER A 337  ? VAL A 346  ? SER A 355  VAL A 364  1 ? 10 
HELX_P HELX_P11 AB2 THR A 363  ? ASN A 370  ? THR A 381  ASN A 388  1 ? 8  
HELX_P HELX_P12 AB3 ASN A 370  ? CYS A 400  ? ASN A 388  CYS A 418  1 ? 31 
HELX_P HELX_P13 AB4 HIS A 402  ? GLY A 413  ? HIS A 420  GLY A 431  1 ? 12 
HELX_P HELX_P14 AB5 GLN A 421  ? GLN A 454  ? GLN A 439  GLN A 472  1 ? 34 
HELX_P HELX_P15 AB6 GLU A 459  ? ASP A 464  ? GLU A 477  ASP A 482  5 ? 6  
HELX_P HELX_P16 AB7 SER A 516  ? LYS A 535  ? SER A 534  LYS A 553  1 ? 20 
HELX_P HELX_P17 AB8 PRO A 552  ? CYS A 559  ? PRO A 570  CYS A 577  1 ? 8  
HELX_P HELX_P18 AB9 VAL A 580  ? MET A 585  ? VAL A 598  MET A 603  1 ? 6  
HELX_P HELX_P19 AC1 ALA A 749  ? LEU A 753  ? ALA A 767  LEU A 771  5 ? 5  
HELX_P HELX_P20 AC2 SER A 769  ? ALA A 786  ? SER A 787  ALA A 804  1 ? 18 
HELX_P HELX_P21 AC3 ALA A 786  ? SER A 792  ? ALA A 804  SER A 810  1 ? 7  
HELX_P HELX_P22 AC4 PRO A 804  ? ARG A 809  ? PRO A 822  ARG A 827  1 ? 6  
HELX_P HELX_P23 AC5 LEU A 856  ? VAL A 860  ? LEU A 874  VAL A 878  5 ? 5  
HELX_P HELX_P24 AC6 SER A 875  ? ALA A 890  ? SER A 893  ALA A 908  1 ? 16 
HELX_P HELX_P25 AC7 THR A 896  ? GLY A 905  ? THR A 914  GLY A 923  1 ? 10 
HELX_P HELX_P26 AC8 ASP A 912  ? GLY A 922  ? ASP A 930  GLY A 940  1 ? 11 
HELX_P HELX_P27 AC9 SER A 924  ? TYR A 937  ? SER A 942  TYR A 955  1 ? 14 
HELX_P HELX_P28 AD1 GLY A 940  ? ASN A 952  ? GLY A 958  ASN A 970  1 ? 13 
HELX_P HELX_P29 AD2 THR A 956  ? ALA A 970  ? THR A 974  ALA A 988  1 ? 15 
HELX_P HELX_P30 AD3 GLU A 1036 ? THR A 1048 ? GLU A 1054 THR A 1066 1 ? 13 
HELX_P HELX_P31 AD4 PHE A 1074 ? ALA A 1106 ? PHE A 1092 ALA A 1124 1 ? 33 
HELX_P HELX_P32 AD5 ASP A 1127 ? LYS A 1149 ? ASP A 1145 LYS A 1167 1 ? 23 
HELX_P HELX_P33 AD6 GLY A 1187 ? GLY A 1193 ? GLY A 1205 GLY A 1211 1 ? 7  
HELX_P HELX_P34 AD7 ASP A 1201 ? LYS A 1210 ? ASP A 1219 LYS A 1228 1 ? 10 
HELX_P HELX_P35 AD8 ALA B 27   ? ARG B 35   ? ALA B 42   ARG B 50   1 ? 9  
HELX_P HELX_P36 AD9 THR B 41   ? LEU B 45   ? THR B 56   LEU B 60   5 ? 5  
HELX_P HELX_P37 AE1 SER B 46   ? GLY B 53   ? SER B 61   GLY B 68   1 ? 8  
HELX_P HELX_P38 AE2 GLY B 59   ? VAL B 79   ? GLY B 74   VAL B 94   1 ? 21 
HELX_P HELX_P39 AE3 SER B 108  ? ILE B 112  ? SER B 123  ILE B 127  5 ? 5  
HELX_P HELX_P40 AE4 LEU B 144  ? HIS B 151  ? LEU B 159  HIS B 166  1 ? 8  
HELX_P HELX_P41 AE5 THR B 206  ? PHE B 225  ? THR B 221  PHE B 240  1 ? 20 
HELX_P HELX_P42 AE6 SER B 228  ? PHE B 232  ? SER B 243  PHE B 247  5 ? 5  
HELX_P HELX_P43 AE7 GLN B 268  ? TYR B 274  ? GLN B 283  TYR B 289  1 ? 7  
HELX_P HELX_P44 AE8 VAL B 301  ? PHE B 313  ? VAL B 316  PHE B 328  1 ? 13 
HELX_P HELX_P45 AE9 PRO B 350  ? GLY B 369  ? PRO B 365  GLY B 384  1 ? 20 
HELX_P HELX_P46 AF1 SER B 383  ? MET B 394  ? SER B 398  MET B 409  1 ? 12 
HELX_P HELX_P47 AF2 THR B 403  ? GLU B 408  ? THR B 418  GLU B 423  5 ? 6  
HELX_P HELX_P48 AF3 HIS B 426  ? SER B 442  ? HIS B 441  SER B 457  1 ? 17 
HELX_P HELX_P49 AF4 LEU C 28   ? ARG C 35   ? LEU C 43   ARG C 50   1 ? 8  
HELX_P HELX_P50 AF5 GLY C 59   ? VAL C 79   ? GLY C 74   VAL C 94   1 ? 21 
HELX_P HELX_P51 AF6 LEU C 144  ? GLU C 150  ? LEU C 159  GLU C 165  1 ? 7  
HELX_P HELX_P52 AF7 HIS C 151  ? ASP C 157  ? HIS C 166  ASP C 172  1 ? 7  
HELX_P HELX_P53 AF8 THR C 206  ? PHE C 225  ? THR C 221  PHE C 240  1 ? 20 
HELX_P HELX_P54 AF9 GLY C 266  ? TYR C 274  ? GLY C 281  TYR C 289  1 ? 9  
HELX_P HELX_P55 AG1 ASN C 277  ? ILE C 281  ? ASN C 292  ILE C 296  5 ? 5  
HELX_P HELX_P56 AG2 VAL C 301  ? SER C 312  ? VAL C 316  SER C 327  1 ? 12 
HELX_P HELX_P57 AG3 VAL C 352  ? GLY C 369  ? VAL C 367  GLY C 384  1 ? 18 
HELX_P HELX_P58 AG4 TYR C 376  ? GLU C 378  ? TYR C 391  GLU C 393  5 ? 3  
HELX_P HELX_P59 AG5 LEU C 384  ? MET C 394  ? LEU C 399  MET C 409  1 ? 11 
HELX_P HELX_P60 AG6 GLU C 404  ? ASN C 409  ? GLU C 419  ASN C 424  1 ? 6  
HELX_P HELX_P61 AG7 LYS C 429  ? SER C 442  ? LYS C 444  SER C 457  1 ? 14 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A ASP 180  OD1 ? ? ? 1_555 G CA  .  CA  ? ? A ASP 198  A CA  1302 1_555 ? ? ? ? ? ? ?            2.471 ? ? 
metalc2  metalc ? ? A ASP 180  OD2 ? ? ? 1_555 H CA  .  CA  ? ? A ASP 198  A CA  1303 1_555 ? ? ? ? ? ? ?            2.303 ? ? 
metalc3  metalc ? ? A GLU 182  OE2 ? ? ? 1_555 H CA  .  CA  ? ? A GLU 200  A CA  1303 1_555 ? ? ? ? ? ? ?            2.359 ? ? 
metalc4  metalc ? ? A HIS 251  O   ? ? ? 1_555 G CA  .  CA  ? ? A HIS 269  A CA  1302 1_555 ? ? ? ? ? ? ?            2.433 ? ? 
metalc5  metalc ? ? A ASP 381  OD2 ? ? ? 1_555 H CA  .  CA  ? ? A ASP 399  A CA  1303 1_555 ? ? ? ? ? ? ?            2.790 ? ? 
metalc6  metalc ? ? A ASP 872  OD1 ? ? ? 1_555 F CA  .  CA  ? ? A ASP 890  A CA  1301 1_555 ? ? ? ? ? ? ?            2.341 ? ? 
metalc7  metalc ? ? A VAL 873  O   ? ? ? 1_555 F CA  .  CA  ? ? A VAL 891  A CA  1301 1_555 ? ? ? ? ? ? ?            2.393 ? ? 
metalc8  metalc ? ? A ASP 1117 OD2 ? ? ? 1_555 F CA  .  CA  ? ? A ASP 1135 A CA  1301 1_555 ? ? ? ? ? ? ?            2.399 ? ? 
metalc9  metalc ? ? F CA  .    CA  ? ? ? 1_555 I DCP .  O2A ? ? A CA  1301 A DCP 1304 1_555 ? ? ? ? ? ? ?            2.422 ? ? 
metalc10 metalc ? ? F CA  .    CA  ? ? ? 1_555 I DCP .  O1A ? ? A CA  1301 A DCP 1304 1_555 ? ? ? ? ? ? ?            3.078 ? ? 
metalc11 metalc ? ? H CA  .    CA  ? ? ? 1_555 D DT  25 OP1 ? ? A CA  1303 P DT  25   1_555 ? ? ? ? ? ? ?            2.404 ? ? 
hydrog1  hydrog ? ? D DG  5    N1  ? ? ? 1_555 E DC  36 N3  ? ? P DG  5    T DC  36   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog2  hydrog ? ? D DG  5    N2  ? ? ? 1_555 E DC  36 O2  ? ? P DG  5    T DC  36   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog3  hydrog ? ? D DG  5    O6  ? ? ? 1_555 E DC  36 N4  ? ? P DG  5    T DC  36   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog4  hydrog ? ? D DC  6    N3  ? ? ? 1_555 E DG  35 N1  ? ? P DC  6    T DG  35   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog5  hydrog ? ? D DC  6    N4  ? ? ? 1_555 E DG  35 O6  ? ? P DC  6    T DG  35   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog6  hydrog ? ? D DC  6    O2  ? ? ? 1_555 E DG  35 N2  ? ? P DC  6    T DG  35   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog7  hydrog ? ? D DG  7    N1  ? ? ? 1_555 E DC  34 N3  ? ? P DG  7    T DC  34   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog8  hydrog ? ? D DG  7    N2  ? ? ? 1_555 E DC  34 O2  ? ? P DG  7    T DC  34   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog9  hydrog ? ? D DG  7    O6  ? ? ? 1_555 E DC  34 N4  ? ? P DG  7    T DC  34   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog10 hydrog ? ? D DG  8    N1  ? ? ? 1_555 E DC  33 N3  ? ? P DG  8    T DC  33   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog11 hydrog ? ? D DG  8    N2  ? ? ? 1_555 E DC  33 O2  ? ? P DG  8    T DC  33   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog12 hydrog ? ? D DG  8    O6  ? ? ? 1_555 E DC  33 N4  ? ? P DG  8    T DC  33   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog13 hydrog ? ? D DT  9    N3  ? ? ? 1_555 E DA  32 N1  ? ? P DT  9    T DA  32   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog14 hydrog ? ? D DT  9    O4  ? ? ? 1_555 E DA  32 N6  ? ? P DT  9    T DA  32   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog15 hydrog ? ? D DC  10   N3  ? ? ? 1_555 E DG  31 N1  ? ? P DC  10   T DG  31   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog16 hydrog ? ? D DC  10   N4  ? ? ? 1_555 E DG  31 O6  ? ? P DC  10   T DG  31   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog17 hydrog ? ? D DC  10   O2  ? ? ? 1_555 E DG  31 N2  ? ? P DC  10   T DG  31   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog18 hydrog ? ? D DG  11   N1  ? ? ? 1_555 E DC  30 N3  ? ? P DG  11   T DC  30   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog19 hydrog ? ? D DG  11   N2  ? ? ? 1_555 E DC  30 O2  ? ? P DG  11   T DC  30   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog20 hydrog ? ? D DG  11   O6  ? ? ? 1_555 E DC  30 N4  ? ? P DG  11   T DC  30   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog21 hydrog ? ? D DA  12   N1  ? ? ? 1_555 E DT  29 N3  ? ? P DA  12   T DT  29   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog22 hydrog ? ? D DA  12   N6  ? ? ? 1_555 E DT  29 O4  ? ? P DA  12   T DT  29   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog23 hydrog ? ? D DG  13   N1  ? ? ? 1_555 E DC  28 N3  ? ? P DG  13   T DC  28   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog24 hydrog ? ? D DG  13   N2  ? ? ? 1_555 E DC  28 O2  ? ? P DG  13   T DC  28   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog25 hydrog ? ? D DG  13   O6  ? ? ? 1_555 E DC  28 N4  ? ? P DG  13   T DC  28   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog26 hydrog ? ? D DT  14   N3  ? ? ? 1_555 E DA  27 N1  ? ? P DT  14   T DA  27   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog27 hydrog ? ? D DT  14   O4  ? ? ? 1_555 E DA  27 N6  ? ? P DT  14   T DA  27   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog28 hydrog ? ? D DC  15   N3  ? ? ? 1_555 E DG  26 N1  ? ? P DC  15   T DG  26   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog29 hydrog ? ? D DC  15   N4  ? ? ? 1_555 E DG  26 O6  ? ? P DC  15   T DG  26   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog30 hydrog ? ? D DC  15   O2  ? ? ? 1_555 E DG  26 N2  ? ? P DC  15   T DG  26   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog31 hydrog ? ? D DT  16   N3  ? ? ? 1_555 E DA  25 N1  ? ? P DT  16   T DA  25   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog32 hydrog ? ? D DT  16   O4  ? ? ? 1_555 E DA  25 N6  ? ? P DT  16   T DA  25   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog33 hydrog ? ? D DA  17   N1  ? ? ? 1_555 E DT  24 N3  ? ? P DA  17   T DT  24   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog34 hydrog ? ? D DA  17   N6  ? ? ? 1_555 E DT  24 O4  ? ? P DA  17   T DT  24   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog35 hydrog ? ? D DG  18   N1  ? ? ? 1_555 E DC  23 N3  ? ? P DG  18   T DC  23   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog36 hydrog ? ? D DG  18   N2  ? ? ? 1_555 E DC  23 O2  ? ? P DG  18   T DC  23   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog37 hydrog ? ? D DG  18   O6  ? ? ? 1_555 E DC  23 N4  ? ? P DG  18   T DC  23   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog38 hydrog ? ? D DA  19   N1  ? ? ? 1_555 E DT  22 N3  ? ? P DA  19   T DT  22   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog39 hydrog ? ? D DA  19   N6  ? ? ? 1_555 E DT  22 O4  ? ? P DA  19   T DT  22   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog40 hydrog ? ? D DG  20   N1  ? ? ? 1_555 E DC  21 N3  ? ? P DG  20   T DC  21   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog41 hydrog ? ? D DG  20   N2  ? ? ? 1_555 E DC  21 O2  ? ? P DG  20   T DC  21   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog42 hydrog ? ? D DG  20   O6  ? ? ? 1_555 E DC  21 N4  ? ? P DG  20   T DC  21   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog43 hydrog ? ? D DG  21   N1  ? ? ? 1_555 E DC  20 N3  ? ? P DG  21   T DC  20   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog44 hydrog ? ? D DG  21   N2  ? ? ? 1_555 E DC  20 O2  ? ? P DG  21   T DC  20   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog45 hydrog ? ? D DG  21   O6  ? ? ? 1_555 E DC  20 N4  ? ? P DG  21   T DC  20   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog46 hydrog ? ? D DA  22   N1  ? ? ? 1_555 E DT  19 N3  ? ? P DA  22   T DT  19   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog47 hydrog ? ? D DA  22   N6  ? ? ? 1_555 E DT  19 O4  ? ? P DA  22   T DT  19   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
metalc ? ? 
hydrog ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OD1 ? A ASP 180  ? A ASP 198  ? 1_555 CA ? G CA . ? A CA 1302 ? 1_555 O   ? A HIS 251  ? A HIS 269  ? 1_555 112.3 ? 
2  OD2 ? A ASP 180  ? A ASP 198  ? 1_555 CA ? H CA . ? A CA 1303 ? 1_555 OE2 ? A GLU 182  ? A GLU 200  ? 1_555 99.6  ? 
3  OD2 ? A ASP 180  ? A ASP 198  ? 1_555 CA ? H CA . ? A CA 1303 ? 1_555 OD2 ? A ASP 381  ? A ASP 399  ? 1_555 128.3 ? 
4  OE2 ? A GLU 182  ? A GLU 200  ? 1_555 CA ? H CA . ? A CA 1303 ? 1_555 OD2 ? A ASP 381  ? A ASP 399  ? 1_555 127.1 ? 
5  OD2 ? A ASP 180  ? A ASP 198  ? 1_555 CA ? H CA . ? A CA 1303 ? 1_555 OP1 ? D DT  25   ? P DT  25   ? 1_555 75.9  ? 
6  OE2 ? A GLU 182  ? A GLU 200  ? 1_555 CA ? H CA . ? A CA 1303 ? 1_555 OP1 ? D DT  25   ? P DT  25   ? 1_555 110.5 ? 
7  OD2 ? A ASP 381  ? A ASP 399  ? 1_555 CA ? H CA . ? A CA 1303 ? 1_555 OP1 ? D DT  25   ? P DT  25   ? 1_555 102.6 ? 
8  OD1 ? A ASP 872  ? A ASP 890  ? 1_555 CA ? F CA . ? A CA 1301 ? 1_555 O   ? A VAL 873  ? A VAL 891  ? 1_555 72.7  ? 
9  OD1 ? A ASP 872  ? A ASP 890  ? 1_555 CA ? F CA . ? A CA 1301 ? 1_555 OD2 ? A ASP 1117 ? A ASP 1135 ? 1_555 91.7  ? 
10 O   ? A VAL 873  ? A VAL 891  ? 1_555 CA ? F CA . ? A CA 1301 ? 1_555 OD2 ? A ASP 1117 ? A ASP 1135 ? 1_555 91.4  ? 
11 OD1 ? A ASP 872  ? A ASP 890  ? 1_555 CA ? F CA . ? A CA 1301 ? 1_555 O2A ? I DCP .    ? A DCP 1304 ? 1_555 155.2 ? 
12 O   ? A VAL 873  ? A VAL 891  ? 1_555 CA ? F CA . ? A CA 1301 ? 1_555 O2A ? I DCP .    ? A DCP 1304 ? 1_555 127.6 ? 
13 OD2 ? A ASP 1117 ? A ASP 1135 ? 1_555 CA ? F CA . ? A CA 1301 ? 1_555 O2A ? I DCP .    ? A DCP 1304 ? 1_555 75.4  ? 
14 OD1 ? A ASP 872  ? A ASP 890  ? 1_555 CA ? F CA . ? A CA 1301 ? 1_555 O1A ? I DCP .    ? A DCP 1304 ? 1_555 102.5 ? 
15 O   ? A VAL 873  ? A VAL 891  ? 1_555 CA ? F CA . ? A CA 1301 ? 1_555 O1A ? I DCP .    ? A DCP 1304 ? 1_555 171.3 ? 
16 OD2 ? A ASP 1117 ? A ASP 1135 ? 1_555 CA ? F CA . ? A CA 1301 ? 1_555 O1A ? I DCP .    ? A DCP 1304 ? 1_555 81.5  ? 
17 O2A ? I DCP .    ? A DCP 1304 ? 1_555 CA ? F CA . ? A CA 1301 ? 1_555 O1A ? I DCP .    ? A DCP 1304 ? 1_555 55.3  ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 LEU 163 B . ? LEU 178 B PRO 164 B ? PRO 179 B 1 -0.51 
2 GLY 349 B . ? GLY 364 B PRO 350 B ? PRO 365 B 1 0.12  
3 LEU 163 C . ? LEU 178 C PRO 164 C ? PRO 179 C 1 -4.04 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 3 ? 
AA3 ? 3 ? 
AA4 ? 2 ? 
AA5 ? 4 ? 
AA6 ? 3 ? 
AA7 ? 2 ? 
AA8 ? 7 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 7 ? 
AB3 ? 2 ? 
AB4 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA8 6 7 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? parallel      
AB1 3 4 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? anti-parallel 
AB2 5 6 ? anti-parallel 
AB2 6 7 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? parallel      
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 167  ? VAL A 169  ? VAL A 185  VAL A 187  
AA1 2 TRP A 157  ? TYR A 160  ? TRP A 175  TYR A 178  
AA1 3 ALA A 201  ? CYS A 206  ? ALA A 219  CYS A 224  
AA1 4 LEU A 193  ? SER A 198  ? LEU A 211  SER A 216  
AA1 5 VAL A 181  ? GLU A 182  ? VAL A 199  GLU A 200  
AA2 1 ALA A 176  ? PHE A 179  ? ALA A 194  PHE A 197  
AA2 2 GLN A 246  ? GLY A 250  ? GLN A 264  GLY A 268  
AA2 3 MET A 271  ? ASP A 275  ? MET A 289  ASP A 293  
AA3 1 LEU A 417  ? VAL A 419  ? LEU A 435  VAL A 437  
AA3 2 TYR A 819  ? ILE A 822  ? TYR A 837  ILE A 840  
AA3 3 VAL A 796  ? LEU A 798  ? VAL A 814  LEU A 816  
AA4 1 LEU A 587  ? THR A 588  ? LEU A 605  THR A 606  
AA4 2 GLN A 762  ? ALA A 763  ? GLN A 780  ALA A 781  
AA5 1 LEU A 594  ? SER A 597  ? LEU A 612  SER A 615  
AA5 2 GLY A 601  ? TYR A 604  ? GLY A 619  TYR A 622  
AA5 3 PHE A 731  ? LYS A 733  ? PHE A 749  LYS A 751  
AA5 4 PRO A 720  ? TYR A 721  ? PRO A 738  TYR A 739  
AA6 1 TYR A 866  ? GLY A 870  ? TYR A 884  GLY A 888  
AA6 2 ARG A 1120 ? ARG A 1124 ? ARG A 1138 ARG A 1142 
AA6 3 PHE A 1111 ? ILE A 1113 ? PHE A 1129 ILE A 1131 
AA7 1 ASP A 1166 ? ILE A 1167 ? ASP A 1184 ILE A 1185 
AA7 2 GLU A 1198 ? ALA A 1199 ? GLU A 1216 ALA A 1217 
AA8 1 VAL B 84   ? ALA B 86   ? VAL B 99   ALA B 101  
AA8 2 PHE B 165  ? PRO B 176  ? PHE B 180  PRO B 191  
AA8 3 VAL B 190  ? PHE B 201  ? VAL B 205  PHE B 216  
AA8 4 VAL B 297  ? ASP B 300  ? VAL B 312  ASP B 315  
AA8 5 LYS B 256  ? THR B 261  ? LYS B 271  THR B 276  
AA8 6 LYS B 244  ? SER B 251  ? LYS B 259  SER B 266  
AA8 7 ASP B 236  ? GLN B 238  ? ASP B 251  GLN B 253  
AA9 1 GLN B 92   ? GLU B 93   ? GLN B 107  GLU B 108  
AA9 2 GLY B 138  ? LEU B 140  ? GLY B 153  LEU B 155  
AA9 3 ARG B 105  ? VAL B 107  ? ARG B 120  VAL B 122  
AA9 4 ARG C 105  ? VAL C 107  ? ARG C 120  VAL C 122  
AB1 1 VAL B 372  ? PRO B 374  ? VAL B 387  PRO B 389  
AB1 2 VAL B 342  ? LEU B 344  ? VAL B 357  LEU B 359  
AB1 3 PHE B 398  ? SER B 399  ? PHE B 413  SER B 414  
AB1 4 ARG B 415  ? SER B 416  ? ARG B 430  SER B 431  
AB2 1 VAL C 84   ? ALA C 86   ? VAL C 99   ALA C 101  
AB2 2 PHE C 165  ? HIS C 175  ? PHE C 180  HIS C 190  
AB2 3 GLY C 191  ? PHE C 201  ? GLY C 206  PHE C 216  
AB2 4 LEU C 295  ? ASP C 300  ? LEU C 310  ASP C 315  
AB2 5 GLY C 255  ? ASN C 264  ? GLY C 270  ASN C 279  
AB2 6 LYS C 244  ? PHE C 252  ? LYS C 259  PHE C 267  
AB2 7 PHE C 232  ? GLN C 238  ? PHE C 247  GLN C 253  
AB3 1 GLN C 92   ? GLU C 93   ? GLN C 107  GLU C 108  
AB3 2 LYS C 139  ? LEU C 140  ? LYS C 154  LEU C 155  
AB4 1 VAL C 372  ? PRO C 374  ? VAL C 387  PRO C 389  
AB4 2 ILE C 340  ? LEU C 344  ? ILE C 355  LEU C 359  
AB4 3 VAL C 396  ? LEU C 401  ? VAL C 411  LEU C 416  
AB4 4 LEU C 411  ? SER C 416  ? LEU C 426  SER C 431  
AB4 5 LYS C 422  ? HIS C 426  ? LYS C 437  HIS C 441  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O VAL A 169  ? O VAL A 187  N TRP A 157  ? N TRP A 175  
AA1 2 3 N THR A 158  ? N THR A 176  O SER A 204  ? O SER A 222  
AA1 3 4 O TYR A 203  ? O TYR A 221  N ALA A 196  ? N ALA A 214  
AA1 4 5 O LEU A 193  ? O LEU A 211  N GLU A 182  ? N GLU A 200  
AA2 1 2 N LEU A 177  ? N LEU A 195  O VAL A 249  ? O VAL A 267  
AA2 2 3 N GLN A 246  ? N GLN A 264  O ARG A 272  ? O ARG A 290  
AA3 1 2 N LEU A 417  ? N LEU A 435  O ILE A 822  ? O ILE A 840  
AA3 2 3 O TYR A 819  ? O TYR A 837  N LEU A 798  ? N LEU A 816  
AA4 1 2 N THR A 588  ? N THR A 606  O GLN A 762  ? O GLN A 780  
AA5 1 2 N HIS A 595  ? N HIS A 613  O GLY A 603  ? O GLY A 621  
AA5 2 3 N TYR A 604  ? N TYR A 622  O PHE A 732  ? O PHE A 750  
AA5 3 4 O PHE A 731  ? O PHE A 749  N TYR A 721  ? N TYR A 739  
AA6 1 2 N VAL A 869  ? N VAL A 887  O TYR A 1121 ? O TYR A 1139 
AA6 2 3 O ARG A 1120 ? O ARG A 1138 N CYS A 1112 ? N CYS A 1130 
AA7 1 2 N ILE A 1167 ? N ILE A 1185 O GLU A 1198 ? O GLU A 1216 
AA8 1 2 N PHE B 85   ? N PHE B 100  O GLY B 166  ? O GLY B 181  
AA8 2 3 N HIS B 175  ? N HIS B 190  O GLY B 191  ? O GLY B 206  
AA8 3 4 N LEU B 198  ? N LEU B 213  O VAL B 297  ? O VAL B 312  
AA8 4 5 O ASP B 300  ? O ASP B 315  N ILE B 259  ? N ILE B 274  
AA8 5 6 O GLU B 260  ? O GLU B 275  N LEU B 248  ? N LEU B 263  
AA8 6 7 O GLY B 245  ? O GLY B 260  N CYS B 237  ? N CYS B 252  
AA9 1 2 N GLU B 93   ? N GLU B 108  O LYS B 139  ? O LYS B 154  
AA9 2 3 O GLY B 138  ? O GLY B 153  N LEU B 106  ? N LEU B 121  
AA9 3 4 N VAL B 107  ? N VAL B 122  O ARG C 105  ? O ARG C 120  
AB1 1 2 O TRP B 373  ? O TRP B 388  N VAL B 342  ? N VAL B 357  
AB1 2 3 N ALA B 343  ? N ALA B 358  O PHE B 398  ? O PHE B 413  
AB1 3 4 N SER B 399  ? N SER B 414  O ARG B 415  ? O ARG B 430  
AB2 1 2 N PHE C 85   ? N PHE C 100  O ALA C 168  ? O ALA C 183  
AB2 2 3 N CYS C 173  ? N CYS C 188  O LYS C 193  ? O LYS C 208  
AB2 3 4 N LEU C 198  ? N LEU C 213  O VAL C 297  ? O VAL C 312  
AB2 4 5 O ASP C 300  ? O ASP C 315  N ILE C 259  ? N ILE C 274  
AB2 5 6 O LEU C 262  ? O LEU C 277  N SER C 246  ? N SER C 261  
AB2 6 7 O TYR C 249  ? O TYR C 264  N SER C 233  ? N SER C 248  
AB3 1 2 N GLU C 93   ? N GLU C 108  O LYS C 139  ? O LYS C 154  
AB4 1 2 O TRP C 373  ? O TRP C 388  N VAL C 342  ? N VAL C 357  
AB4 2 3 N LYS C 341  ? N LYS C 356  O PHE C 398  ? O PHE C 413  
AB4 3 4 N LEU C 401  ? N LEU C 416  O GLN C 413  ? O GLN C 428  
AB4 4 5 N LEU C 414  ? N LEU C 429  O GLU C 423  ? O GLU C 438  
# 
_pdbx_entry_details.entry_id                   9IC3 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO A 73   ? ? -57.59  -5.84   
2  1 ILE A 87   ? ? -122.19 -61.58  
3  1 TRP A 171  ? ? -93.63  59.11   
4  1 ASN A 388  ? ? -90.13  43.94   
5  1 GLN A 497  ? ? 62.62   -137.00 
6  1 PRO A 589  ? ? -70.00  69.16   
7  1 PRO A 783  ? ? -68.31  -174.81 
8  1 ARG A 852  ? ? 80.71   13.23   
9  1 THR A 858  ? ? -91.71  -62.73  
10 1 ARG A 869  ? ? -162.50 111.17  
11 1 VAL A 1074 ? ? -92.42  -61.21  
12 1 GLN A 1089 ? ? 63.02   -127.24 
13 1 CYS A 1130 ? ? -99.47  -60.23  
14 1 HIS A 1134 ? ? 59.68   -120.27 
15 1 ASP A 1184 ? ? -61.86  98.60   
16 1 LEU A 1218 ? ? -79.34  -166.94 
17 1 HIS B 166  ? ? -97.13  36.02   
18 1 VAL B 168  ? ? -124.41 -58.70  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9IC3 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9IC3 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.96 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               516159 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.name 
_em_entity_assembly.details 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
_em_entity_assembly.entity_id_list 
1 0 'MULTIPLE SOURCES' COMPLEX                           
'Chimeric mitochondrial DNA polymerase gamma ternary complex (hAmB) in mouse-like error-editing conformer (composite)' ? ? ? 
'1, 2, 3, 4' 
2 1 RECOMBINANT        'ORGANELLE OR CELLULAR COMPONENT' 'DNA polymerase subunit gamma-1' ? ? ? 1            
3 1 RECOMBINANT        'ORGANELLE OR CELLULAR COMPONENT' 'DNA polymerase subunit gamma-2' ? ? ? 2            
# 
_em_imaging.entry_id                        9IC3 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2200 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           105000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
_em_imaging.objective_aperture              ? 
_em_imaging.microscope_serial_number        ? 
_em_imaging.microscope_version              ? 
# 
_em_vitrification.entry_id              9IC3 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9IC3 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9IC3 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 19   ? A MET 1    
2   1 Y 1 A HIS 20   ? A HIS 2    
3   1 Y 1 A HIS 21   ? A HIS 3    
4   1 Y 1 A HIS 22   ? A HIS 4    
5   1 Y 1 A HIS 23   ? A HIS 5    
6   1 Y 1 A HIS 24   ? A HIS 6    
7   1 Y 1 A HIS 25   ? A HIS 7    
8   1 Y 1 A VAL 26   ? A VAL 8    
9   1 Y 1 A SER 27   ? A SER 9    
10  1 Y 1 A SER 28   ? A SER 10   
11  1 Y 1 A SER 29   ? A SER 11   
12  1 Y 1 A VAL 30   ? A VAL 12   
13  1 Y 1 A PRO 31   ? A PRO 13   
14  1 Y 1 A ALA 32   ? A ALA 14   
15  1 Y 1 A SER 33   ? A SER 15   
16  1 Y 1 A ASP 34   ? A ASP 16   
17  1 Y 1 A PRO 35   ? A PRO 17   
18  1 Y 1 A SER 36   ? A SER 18   
19  1 Y 1 A ASP 37   ? A ASP 19   
20  1 Y 1 A GLY 38   ? A GLY 20   
21  1 Y 1 A GLN 39   ? A GLN 21   
22  1 Y 1 A ARG 40   ? A ARG 22   
23  1 Y 1 A ARG 41   ? A ARG 23   
24  1 Y 1 A ARG 42   ? A ARG 24   
25  1 Y 1 A GLN 43   ? A GLN 25   
26  1 Y 1 A GLN 44   ? A GLN 26   
27  1 Y 1 A GLN 45   ? A GLN 27   
28  1 Y 1 A GLN 46   ? A GLN 28   
29  1 Y 1 A GLN 47   ? A GLN 29   
30  1 Y 1 A GLN 48   ? A GLN 30   
31  1 Y 1 A GLN 49   ? A GLN 31   
32  1 Y 1 A GLN 50   ? A GLN 32   
33  1 Y 1 A GLN 51   ? A GLN 33   
34  1 Y 1 A GLN 52   ? A GLN 34   
35  1 Y 1 A GLN 53   ? A GLN 35   
36  1 Y 1 A GLN 54   ? A GLN 36   
37  1 Y 1 A GLN 55   ? A GLN 37   
38  1 Y 1 A PRO 56   ? A PRO 38   
39  1 Y 1 A GLN 57   ? A GLN 39   
40  1 Y 1 A GLN 58   ? A GLN 40   
41  1 Y 1 A PRO 59   ? A PRO 41   
42  1 Y 1 A GLN 60   ? A GLN 42   
43  1 Y 1 A VAL 61   ? A VAL 43   
44  1 Y 1 A LEU 62   ? A LEU 44   
45  1 Y 1 A SER 63   ? A SER 45   
46  1 Y 1 A SER 64   ? A SER 46   
47  1 Y 1 A GLU 65   ? A GLU 47   
48  1 Y 1 A GLY 66   ? A GLY 48   
49  1 Y 1 A GLY 67   ? A GLY 49   
50  1 Y 1 A GLN 68   ? A GLN 50   
51  1 Y 1 A LEU 69   ? A LEU 51   
52  1 Y 1 A THR 251  ? A THR 233  
53  1 Y 1 A GLY 252  ? A GLY 234  
54  1 Y 1 A ALA 253  ? A ALA 235  
55  1 Y 1 A SER 254  ? A SER 236  
56  1 Y 1 A SER 255  ? A SER 237  
57  1 Y 1 A PRO 256  ? A PRO 238  
58  1 Y 1 A THR 257  ? A THR 239  
59  1 Y 1 A GLN 258  ? A GLN 240  
60  1 Y 1 A ARG 259  ? A ARG 241  
61  1 Y 1 A ASP 260  ? A ASP 242  
62  1 Y 1 A TRP 261  ? A TRP 243  
63  1 Y 1 A ALA 314  ? A ALA 296  
64  1 Y 1 A ALA 315  ? A ALA 297  
65  1 Y 1 A LYS 316  ? A LYS 298  
66  1 Y 1 A GLN 317  ? A GLN 299  
67  1 Y 1 A GLY 318  ? A GLY 300  
68  1 Y 1 A LYS 319  ? A LYS 301  
69  1 Y 1 A HIS 320  ? A HIS 302  
70  1 Y 1 A LYS 321  ? A LYS 303  
71  1 Y 1 A VAL 322  ? A VAL 304  
72  1 Y 1 A GLN 323  ? A GLN 305  
73  1 Y 1 A PRO 324  ? A PRO 306  
74  1 Y 1 A PRO 325  ? A PRO 307  
75  1 Y 1 A THR 326  ? A THR 308  
76  1 Y 1 A LYS 327  ? A LYS 309  
77  1 Y 1 A GLN 328  ? A GLN 310  
78  1 Y 1 A GLY 329  ? A GLY 311  
79  1 Y 1 A GLN 330  ? A GLN 312  
80  1 Y 1 A LYS 331  ? A LYS 313  
81  1 Y 1 A SER 332  ? A SER 314  
82  1 Y 1 A GLN 333  ? A GLN 315  
83  1 Y 1 A ARG 334  ? A ARG 316  
84  1 Y 1 A LYS 335  ? A LYS 317  
85  1 Y 1 A ALA 336  ? A ALA 318  
86  1 Y 1 A ARG 337  ? A ARG 319  
87  1 Y 1 A ARG 338  ? A ARG 320  
88  1 Y 1 A GLY 339  ? A GLY 321  
89  1 Y 1 A PRO 340  ? A PRO 322  
90  1 Y 1 A ALA 341  ? A ALA 323  
91  1 Y 1 A ILE 342  ? A ILE 324  
92  1 Y 1 A SER 343  ? A SER 325  
93  1 Y 1 A SER 344  ? A SER 326  
94  1 Y 1 A TRP 345  ? A TRP 327  
95  1 Y 1 A ASP 346  ? A ASP 328  
96  1 Y 1 A LYS 499  ? A LYS 481  
97  1 Y 1 A ALA 500  ? A ALA 482  
98  1 Y 1 A LYS 501  ? A LYS 483  
99  1 Y 1 A LYS 502  ? A LYS 484  
100 1 Y 1 A VAL 503  ? A VAL 485  
101 1 Y 1 A LYS 504  ? A LYS 486  
102 1 Y 1 A LYS 505  ? A LYS 487  
103 1 Y 1 A GLU 506  ? A GLU 488  
104 1 Y 1 A PRO 507  ? A PRO 489  
105 1 Y 1 A ALA 508  ? A ALA 490  
106 1 Y 1 A THR 509  ? A THR 491  
107 1 Y 1 A ALA 510  ? A ALA 492  
108 1 Y 1 A SER 511  ? A SER 493  
109 1 Y 1 A LYS 512  ? A LYS 494  
110 1 Y 1 A LEU 513  ? A LEU 495  
111 1 Y 1 A PRO 514  ? A PRO 496  
112 1 Y 1 A ILE 515  ? A ILE 497  
113 1 Y 1 A GLU 516  ? A GLU 498  
114 1 Y 1 A GLY 517  ? A GLY 499  
115 1 Y 1 A ALA 518  ? A ALA 500  
116 1 Y 1 A GLY 519  ? A GLY 501  
117 1 Y 1 A ALA 520  ? A ALA 502  
118 1 Y 1 A PRO 521  ? A PRO 503  
119 1 Y 1 A GLY 522  ? A GLY 504  
120 1 Y 1 A ASP 523  ? A ASP 505  
121 1 Y 1 A PRO 524  ? A PRO 506  
122 1 Y 1 A MET 525  ? A MET 507  
123 1 Y 1 A ASP 526  ? A ASP 508  
124 1 Y 1 A GLN 527  ? A GLN 509  
125 1 Y 1 A GLU 528  ? A GLU 510  
126 1 Y 1 A ASP 529  ? A ASP 511  
127 1 Y 1 A PRO 625  ? A PRO 607  
128 1 Y 1 A GLY 626  ? A GLY 608  
129 1 Y 1 A ARG 627  ? A ARG 609  
130 1 Y 1 A ARG 628  ? A ARG 610  
131 1 Y 1 A ASP 629  ? A ASP 611  
132 1 Y 1 A ASN 630  ? A ASN 612  
133 1 Y 1 A LEU 631  ? A LEU 613  
134 1 Y 1 A ALA 632  ? A ALA 614  
135 1 Y 1 A LYS 633  ? A LYS 615  
136 1 Y 1 A LEU 634  ? A LEU 616  
137 1 Y 1 A PRO 635  ? A PRO 617  
138 1 Y 1 A THR 636  ? A THR 618  
139 1 Y 1 A GLY 637  ? A GLY 619  
140 1 Y 1 A THR 638  ? A THR 620  
141 1 Y 1 A THR 639  ? A THR 621  
142 1 Y 1 A LEU 640  ? A LEU 622  
143 1 Y 1 A GLU 641  ? A GLU 623  
144 1 Y 1 A SER 642  ? A SER 624  
145 1 Y 1 A ALA 643  ? A ALA 625  
146 1 Y 1 A GLY 644  ? A GLY 626  
147 1 Y 1 A VAL 645  ? A VAL 627  
148 1 Y 1 A VAL 646  ? A VAL 628  
149 1 Y 1 A CYS 647  ? A CYS 629  
150 1 Y 1 A PRO 648  ? A PRO 630  
151 1 Y 1 A TYR 649  ? A TYR 631  
152 1 Y 1 A ARG 650  ? A ARG 632  
153 1 Y 1 A ALA 651  ? A ALA 633  
154 1 Y 1 A ILE 652  ? A ILE 634  
155 1 Y 1 A GLU 653  ? A GLU 635  
156 1 Y 1 A SER 654  ? A SER 636  
157 1 Y 1 A LEU 655  ? A LEU 637  
158 1 Y 1 A TYR 656  ? A TYR 638  
159 1 Y 1 A ARG 657  ? A ARG 639  
160 1 Y 1 A LYS 658  ? A LYS 640  
161 1 Y 1 A HIS 659  ? A HIS 641  
162 1 Y 1 A CYS 660  ? A CYS 642  
163 1 Y 1 A LEU 661  ? A LEU 643  
164 1 Y 1 A GLU 662  ? A GLU 644  
165 1 Y 1 A GLN 663  ? A GLN 645  
166 1 Y 1 A GLY 664  ? A GLY 646  
167 1 Y 1 A LYS 665  ? A LYS 647  
168 1 Y 1 A GLN 666  ? A GLN 648  
169 1 Y 1 A GLN 667  ? A GLN 649  
170 1 Y 1 A LEU 668  ? A LEU 650  
171 1 Y 1 A MET 669  ? A MET 651  
172 1 Y 1 A PRO 670  ? A PRO 652  
173 1 Y 1 A GLN 671  ? A GLN 653  
174 1 Y 1 A GLU 672  ? A GLU 654  
175 1 Y 1 A ALA 673  ? A ALA 655  
176 1 Y 1 A GLY 674  ? A GLY 656  
177 1 Y 1 A LEU 675  ? A LEU 657  
178 1 Y 1 A ALA 676  ? A ALA 658  
179 1 Y 1 A GLU 677  ? A GLU 659  
180 1 Y 1 A GLU 678  ? A GLU 660  
181 1 Y 1 A PHE 679  ? A PHE 661  
182 1 Y 1 A LEU 680  ? A LEU 662  
183 1 Y 1 A LEU 681  ? A LEU 663  
184 1 Y 1 A THR 682  ? A THR 664  
185 1 Y 1 A ASP 683  ? A ASP 665  
186 1 Y 1 A ASN 684  ? A ASN 666  
187 1 Y 1 A SER 685  ? A SER 667  
188 1 Y 1 A ALA 686  ? A ALA 668  
189 1 Y 1 A ILE 687  ? A ILE 669  
190 1 Y 1 A TRP 688  ? A TRP 670  
191 1 Y 1 A GLN 689  ? A GLN 671  
192 1 Y 1 A THR 690  ? A THR 672  
193 1 Y 1 A VAL 691  ? A VAL 673  
194 1 Y 1 A GLU 692  ? A GLU 674  
195 1 Y 1 A GLU 693  ? A GLU 675  
196 1 Y 1 A LEU 694  ? A LEU 676  
197 1 Y 1 A ASP 695  ? A ASP 677  
198 1 Y 1 A TYR 696  ? A TYR 678  
199 1 Y 1 A LEU 697  ? A LEU 679  
200 1 Y 1 A GLU 698  ? A GLU 680  
201 1 Y 1 A VAL 699  ? A VAL 681  
202 1 Y 1 A GLU 700  ? A GLU 682  
203 1 Y 1 A ALA 701  ? A ALA 683  
204 1 Y 1 A GLU 702  ? A GLU 684  
205 1 Y 1 A ALA 703  ? A ALA 685  
206 1 Y 1 A LYS 704  ? A LYS 686  
207 1 Y 1 A MET 705  ? A MET 687  
208 1 Y 1 A GLU 706  ? A GLU 688  
209 1 Y 1 A ASN 707  ? A ASN 689  
210 1 Y 1 A LEU 708  ? A LEU 690  
211 1 Y 1 A ARG 709  ? A ARG 691  
212 1 Y 1 A ALA 710  ? A ALA 692  
213 1 Y 1 A ALA 711  ? A ALA 693  
214 1 Y 1 A VAL 712  ? A VAL 694  
215 1 Y 1 A PRO 713  ? A PRO 695  
216 1 Y 1 A GLY 714  ? A GLY 696  
217 1 Y 1 A GLN 715  ? A GLN 697  
218 1 Y 1 A PRO 716  ? A PRO 698  
219 1 Y 1 A LEU 717  ? A LEU 699  
220 1 Y 1 A ALA 718  ? A ALA 700  
221 1 Y 1 A LEU 719  ? A LEU 701  
222 1 Y 1 A THR 720  ? A THR 702  
223 1 Y 1 A ALA 721  ? A ALA 703  
224 1 Y 1 A ARG 722  ? A ARG 704  
225 1 Y 1 A GLY 723  ? A GLY 705  
226 1 Y 1 A GLY 724  ? A GLY 706  
227 1 Y 1 A PRO 725  ? A PRO 707  
228 1 Y 1 A LYS 726  ? A LYS 708  
229 1 Y 1 A ASP 727  ? A ASP 709  
230 1 Y 1 A THR 728  ? A THR 710  
231 1 Y 1 A GLN 729  ? A GLN 711  
232 1 Y 1 A PRO 730  ? A PRO 712  
233 1 Y 1 A SER 731  ? A SER 713  
234 1 Y 1 A TYR 732  ? A TYR 714  
235 1 Y 1 A HIS 733  ? A HIS 715  
236 1 Y 1 A HIS 734  ? A HIS 716  
237 1 Y 1 A GLY 735  ? A GLY 717  
238 1 Y 1 A MET 774  ? A MET 756  
239 1 Y 1 A GLU 775  ? A GLU 757  
240 1 Y 1 A ASP 776  ? A ASP 758  
241 1 Y 1 A GLY 777  ? A GLY 759  
242 1 Y 1 A THR 778  ? A THR 760  
243 1 Y 1 A TRP 994  ? A TRP 976  
244 1 Y 1 A TYR 995  ? A TYR 977  
245 1 Y 1 A ARG 996  ? A ARG 978  
246 1 Y 1 A LEU 997  ? A LEU 979  
247 1 Y 1 A SER 998  ? A SER 980  
248 1 Y 1 A ASP 999  ? A ASP 981  
249 1 Y 1 A GLU 1000 ? A GLU 982  
250 1 Y 1 A GLY 1001 ? A GLY 983  
251 1 Y 1 A GLU 1002 ? A GLU 984  
252 1 Y 1 A TRP 1003 ? A TRP 985  
253 1 Y 1 A LEU 1004 ? A LEU 986  
254 1 Y 1 A VAL 1005 ? A VAL 987  
255 1 Y 1 A ARG 1006 ? A ARG 988  
256 1 Y 1 A GLU 1007 ? A GLU 989  
257 1 Y 1 A LEU 1008 ? A LEU 990  
258 1 Y 1 A ASN 1009 ? A ASN 991  
259 1 Y 1 A LEU 1010 ? A LEU 992  
260 1 Y 1 A PRO 1011 ? A PRO 993  
261 1 Y 1 A VAL 1012 ? A VAL 994  
262 1 Y 1 A ASP 1013 ? A ASP 995  
263 1 Y 1 A ARG 1014 ? A ARG 996  
264 1 Y 1 A THR 1015 ? A THR 997  
265 1 Y 1 A GLU 1016 ? A GLU 998  
266 1 Y 1 A GLY 1017 ? A GLY 999  
267 1 Y 1 A GLY 1018 ? A GLY 1000 
268 1 Y 1 A TRP 1019 ? A TRP 1001 
269 1 Y 1 A ILE 1020 ? A ILE 1002 
270 1 Y 1 A SER 1021 ? A SER 1003 
271 1 Y 1 A LEU 1022 ? A LEU 1004 
272 1 Y 1 A GLN 1023 ? A GLN 1005 
273 1 Y 1 A ASP 1024 ? A ASP 1006 
274 1 Y 1 A LEU 1025 ? A LEU 1007 
275 1 Y 1 A ARG 1026 ? A ARG 1008 
276 1 Y 1 A LYS 1027 ? A LYS 1009 
277 1 Y 1 A VAL 1028 ? A VAL 1010 
278 1 Y 1 A GLN 1029 ? A GLN 1011 
279 1 Y 1 A ARG 1030 ? A ARG 1012 
280 1 Y 1 A GLU 1031 ? A GLU 1013 
281 1 Y 1 A THR 1032 ? A THR 1014 
282 1 Y 1 A ALA 1033 ? A ALA 1015 
283 1 Y 1 A ARG 1034 ? A ARG 1016 
284 1 Y 1 A LYS 1035 ? A LYS 1017 
285 1 Y 1 A SER 1036 ? A SER 1018 
286 1 Y 1 A GLN 1037 ? A GLN 1019 
287 1 Y 1 A TRP 1038 ? A TRP 1020 
288 1 Y 1 A LYS 1039 ? A LYS 1021 
289 1 Y 1 A LYS 1040 ? A LYS 1022 
290 1 Y 1 A TRP 1041 ? A TRP 1023 
291 1 Y 1 A GLU 1042 ? A GLU 1024 
292 1 Y 1 A VAL 1043 ? A VAL 1025 
293 1 Y 1 A VAL 1044 ? A VAL 1026 
294 1 Y 1 A ALA 1045 ? A ALA 1027 
295 1 Y 1 A GLU 1046 ? A GLU 1028 
296 1 Y 1 A ARG 1047 ? A ARG 1029 
297 1 Y 1 A ALA 1048 ? A ALA 1030 
298 1 Y 1 A ARG 1234 ? A ARG 1216 
299 1 Y 1 A SER 1235 ? A SER 1217 
300 1 Y 1 A GLN 1236 ? A GLN 1218 
301 1 Y 1 A PRO 1237 ? A PRO 1219 
302 1 Y 1 A GLY 1238 ? A GLY 1220 
303 1 Y 1 A PRO 1239 ? A PRO 1221 
304 1 Y 1 B MET 16   ? B MET 1    
305 1 Y 1 B TRP 17   ? B TRP 2    
306 1 Y 1 B LEU 18   ? B LEU 3    
307 1 Y 1 B SER 19   ? B SER 4    
308 1 Y 1 B GLY 20   ? B GLY 5    
309 1 Y 1 B TYR 21   ? B TYR 6    
310 1 Y 1 B ALA 22   ? B ALA 7    
311 1 Y 1 B GLY 23   ? B GLY 8    
312 1 Y 1 B PRO 24   ? B PRO 9    
313 1 Y 1 B ALA 25   ? B ALA 10   
314 1 Y 1 B ASP 26   ? B ASP 11   
315 1 Y 1 B GLY 27   ? B GLY 12   
316 1 Y 1 B THR 28   ? B THR 13   
317 1 Y 1 B GLN 29   ? B GLN 14   
318 1 Y 1 B GLN 30   ? B GLN 15   
319 1 Y 1 B PRO 31   ? B PRO 16   
320 1 Y 1 B ASP 32   ? B ASP 17   
321 1 Y 1 B ALA 33   ? B ALA 18   
322 1 Y 1 B PRO 34   ? B PRO 19   
323 1 Y 1 B GLU 35   ? B GLU 20   
324 1 Y 1 B HIS 36   ? B HIS 21   
325 1 Y 1 B ALA 37   ? B ALA 22   
326 1 Y 1 B VAL 38   ? B VAL 23   
327 1 Y 1 B ALA 39   ? B ALA 24   
328 1 Y 1 B ARG 40   ? B ARG 25   
329 1 Y 1 B SER 111  ? B SER 96   
330 1 Y 1 B SER 112  ? B SER 97   
331 1 Y 1 B GLN 113  ? B GLN 98   
332 1 Y 1 B PRO 114  ? B PRO 99   
333 1 Y 1 B ARG 115  ? B ARG 100  
334 1 Y 1 B ARG 128  ? B ARG 113  
335 1 Y 1 B GLU 129  ? B GLU 114  
336 1 Y 1 B ILE 130  ? B ILE 115  
337 1 Y 1 B LEU 131  ? B LEU 116  
338 1 Y 1 B GLN 132  ? B GLN 117  
339 1 Y 1 B ASP 133  ? B ASP 118  
340 1 Y 1 B ARG 134  ? B ARG 119  
341 1 Y 1 B GLU 135  ? B GLU 120  
342 1 Y 1 B PRO 136  ? B PRO 121  
343 1 Y 1 B SER 137  ? B SER 122  
344 1 Y 1 B LYS 138  ? B LYS 123  
345 1 Y 1 B GLU 139  ? B GLU 124  
346 1 Y 1 B GLN 140  ? B GLN 125  
347 1 Y 1 B LEU 141  ? B LEU 126  
348 1 Y 1 B VAL 142  ? B VAL 127  
349 1 Y 1 B ALA 143  ? B ALA 128  
350 1 Y 1 B PHE 144  ? B PHE 129  
351 1 Y 1 B CYS 170  ? B CYS 155  
352 1 Y 1 B LEU 171  ? B LEU 156  
353 1 Y 1 B ASP 172  ? B ASP 157  
354 1 Y 1 B LEU 173  ? B LEU 158  
355 1 Y 1 B VAL 174  ? B VAL 159  
356 1 Y 1 B ASN 175  ? B ASN 160  
357 1 Y 1 B SER 193  ? B SER 178  
358 1 Y 1 B ASN 194  ? B ASN 179  
359 1 Y 1 B SER 195  ? B SER 180  
360 1 Y 1 B ASN 196  ? B ASN 181  
361 1 Y 1 B GLN 197  ? B GLN 182  
362 1 Y 1 B THR 198  ? B THR 183  
363 1 Y 1 B PRO 199  ? B PRO 184  
364 1 Y 1 B SER 200  ? B SER 185  
365 1 Y 1 B SER 201  ? B SER 186  
366 1 Y 1 B VAL 202  ? B VAL 187  
367 1 Y 1 B GLN 297  ? B GLN 282  
368 1 Y 1 B GLY 298  ? B GLY 283  
369 1 Y 1 B ARG 299  ? B ARG 284  
370 1 Y 1 B ASP 300  ? B ASP 285  
371 1 Y 1 B GLY 301  ? B GLY 286  
372 1 Y 1 B ARG 302  ? B ARG 287  
373 1 Y 1 B LYS 303  ? B LYS 288  
374 1 Y 1 B ALA 331  ? B ALA 316  
375 1 Y 1 B GLU 332  ? B GLU 317  
376 1 Y 1 B ASN 333  ? B ASN 318  
377 1 Y 1 B SER 334  ? B SER 319  
378 1 Y 1 B PHE 335  ? B PHE 320  
379 1 Y 1 B ALA 336  ? B ALA 321  
380 1 Y 1 B ARG 337  ? B ARG 322  
381 1 Y 1 B LYS 338  ? B LYS 323  
382 1 Y 1 B LYS 339  ? B LYS 324  
383 1 Y 1 B SER 340  ? B SER 325  
384 1 Y 1 B LEU 341  ? B LEU 326  
385 1 Y 1 B VAL 459  ? B VAL 444  
386 1 Y 1 B HIS 460  ? B HIS 445  
387 1 Y 1 B HIS 461  ? B HIS 446  
388 1 Y 1 B HIS 462  ? B HIS 447  
389 1 Y 1 B HIS 463  ? B HIS 448  
390 1 Y 1 B HIS 464  ? B HIS 449  
391 1 Y 1 B HIS 465  ? B HIS 450  
392 1 Y 1 C MET 16   ? C MET 1    
393 1 Y 1 C TRP 17   ? C TRP 2    
394 1 Y 1 C LEU 18   ? C LEU 3    
395 1 Y 1 C SER 19   ? C SER 4    
396 1 Y 1 C GLY 20   ? C GLY 5    
397 1 Y 1 C TYR 21   ? C TYR 6    
398 1 Y 1 C ALA 22   ? C ALA 7    
399 1 Y 1 C GLY 23   ? C GLY 8    
400 1 Y 1 C PRO 24   ? C PRO 9    
401 1 Y 1 C ALA 25   ? C ALA 10   
402 1 Y 1 C ASP 26   ? C ASP 11   
403 1 Y 1 C GLY 27   ? C GLY 12   
404 1 Y 1 C THR 28   ? C THR 13   
405 1 Y 1 C GLN 29   ? C GLN 14   
406 1 Y 1 C GLN 30   ? C GLN 15   
407 1 Y 1 C PRO 31   ? C PRO 16   
408 1 Y 1 C ASP 32   ? C ASP 17   
409 1 Y 1 C ALA 33   ? C ALA 18   
410 1 Y 1 C PRO 34   ? C PRO 19   
411 1 Y 1 C GLU 35   ? C GLU 20   
412 1 Y 1 C HIS 36   ? C HIS 21   
413 1 Y 1 C ALA 37   ? C ALA 22   
414 1 Y 1 C VAL 38   ? C VAL 23   
415 1 Y 1 C ALA 39   ? C ALA 24   
416 1 Y 1 C ARG 40   ? C ARG 25   
417 1 Y 1 C GLU 41   ? C GLU 26   
418 1 Y 1 C GLY 55   ? C GLY 40   
419 1 Y 1 C THR 56   ? C THR 41   
420 1 Y 1 C PRO 57   ? C PRO 42   
421 1 Y 1 C GLN 58   ? C GLN 43   
422 1 Y 1 C GLN 59   ? C GLN 44   
423 1 Y 1 C LEU 60   ? C LEU 45   
424 1 Y 1 C SER 61   ? C SER 46   
425 1 Y 1 C THR 62   ? C THR 47   
426 1 Y 1 C ALA 63   ? C ALA 48   
427 1 Y 1 C ALA 64   ? C ALA 49   
428 1 Y 1 C LEU 65   ? C LEU 50   
429 1 Y 1 C LEU 66   ? C LEU 51   
430 1 Y 1 C SER 67   ? C SER 52   
431 1 Y 1 C GLY 68   ? C GLY 53   
432 1 Y 1 C CYS 69   ? C CYS 54   
433 1 Y 1 C HIS 70   ? C HIS 55   
434 1 Y 1 C ALA 71   ? C ALA 56   
435 1 Y 1 C ILE 127  ? C ILE 112  
436 1 Y 1 C ARG 128  ? C ARG 113  
437 1 Y 1 C GLU 129  ? C GLU 114  
438 1 Y 1 C ILE 130  ? C ILE 115  
439 1 Y 1 C LEU 131  ? C LEU 116  
440 1 Y 1 C GLN 132  ? C GLN 117  
441 1 Y 1 C ASP 133  ? C ASP 118  
442 1 Y 1 C ARG 134  ? C ARG 119  
443 1 Y 1 C GLU 135  ? C GLU 120  
444 1 Y 1 C PRO 136  ? C PRO 121  
445 1 Y 1 C SER 137  ? C SER 122  
446 1 Y 1 C LYS 138  ? C LYS 123  
447 1 Y 1 C GLU 139  ? C GLU 124  
448 1 Y 1 C GLN 140  ? C GLN 125  
449 1 Y 1 C LEU 141  ? C LEU 126  
450 1 Y 1 C VAL 142  ? C VAL 127  
451 1 Y 1 C ALA 143  ? C ALA 128  
452 1 Y 1 C PHE 144  ? C PHE 129  
453 1 Y 1 C SER 193  ? C SER 178  
454 1 Y 1 C ASN 194  ? C ASN 179  
455 1 Y 1 C SER 195  ? C SER 180  
456 1 Y 1 C ASN 196  ? C ASN 181  
457 1 Y 1 C GLN 197  ? C GLN 182  
458 1 Y 1 C THR 198  ? C THR 183  
459 1 Y 1 C PRO 199  ? C PRO 184  
460 1 Y 1 C SER 200  ? C SER 185  
461 1 Y 1 C SER 201  ? C SER 186  
462 1 Y 1 C VAL 202  ? C VAL 187  
463 1 Y 1 C THR 203  ? C THR 188  
464 1 Y 1 C GLN 297  ? C GLN 282  
465 1 Y 1 C GLY 298  ? C GLY 283  
466 1 Y 1 C ARG 299  ? C ARG 284  
467 1 Y 1 C GLN 329  ? C GLN 314  
468 1 Y 1 C LEU 330  ? C LEU 315  
469 1 Y 1 C ALA 331  ? C ALA 316  
470 1 Y 1 C GLU 332  ? C GLU 317  
471 1 Y 1 C ASN 333  ? C ASN 318  
472 1 Y 1 C SER 334  ? C SER 319  
473 1 Y 1 C PHE 335  ? C PHE 320  
474 1 Y 1 C ALA 336  ? C ALA 321  
475 1 Y 1 C ARG 337  ? C ARG 322  
476 1 Y 1 C LYS 338  ? C LYS 323  
477 1 Y 1 C LYS 339  ? C LYS 324  
478 1 Y 1 C SER 340  ? C SER 325  
479 1 Y 1 C LEU 341  ? C LEU 326  
480 1 Y 1 C GLN 342  ? C GLN 327  
481 1 Y 1 C ARG 343  ? C ARG 328  
482 1 Y 1 C LYS 344  ? C LYS 329  
483 1 Y 1 C GLY 364  ? C GLY 349  
484 1 Y 1 C PRO 365  ? C PRO 350  
485 1 Y 1 C HIS 396  ? C HIS 381  
486 1 Y 1 C SER 397  ? C SER 382  
487 1 Y 1 C ASN 458  ? C ASN 443  
488 1 Y 1 C VAL 459  ? C VAL 444  
489 1 Y 1 C HIS 460  ? C HIS 445  
490 1 Y 1 C HIS 461  ? C HIS 446  
491 1 Y 1 C HIS 462  ? C HIS 447  
492 1 Y 1 C HIS 463  ? C HIS 448  
493 1 Y 1 C HIS 464  ? C HIS 449  
494 1 Y 1 C HIS 465  ? C HIS 450  
495 1 Y 1 P DG  1    ? D DG  1    
496 1 Y 1 P DC  2    ? D DC  2    
497 1 Y 1 P DA  3    ? D DA  3    
498 1 Y 1 P DT  4    ? D DT  4    
499 1 Y 1 T DT  1    ? E DT  1    
500 1 Y 1 T DT  2    ? E DT  2    
501 1 Y 1 T DT  3    ? E DT  3    
502 1 Y 1 T DT  4    ? E DT  4    
503 1 Y 1 T DT  5    ? E DT  5    
504 1 Y 1 T DT  6    ? E DT  6    
505 1 Y 1 T DT  7    ? E DT  7    
506 1 Y 1 T DT  8    ? E DT  8    
507 1 Y 1 T DT  9    ? E DT  9    
508 1 Y 1 T DT  10   ? E DT  10   
509 1 Y 1 T DA  11   ? E DA  11   
510 1 Y 1 T DT  12   ? E DT  12   
511 1 Y 1 T DC  13   ? E DC  13   
512 1 Y 1 T DC  14   ? E DC  14   
513 1 Y 1 T DG  15   ? E DG  15   
514 1 Y 1 T DG  16   ? E DG  16   
515 1 Y 1 T DA  37   ? E DA  37   
516 1 Y 1 T DT  38   ? E DT  38   
517 1 Y 1 T DG  39   ? E DG  39   
518 1 Y 1 T DC  40   ? E DC  40   
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N  N N 1   
ALA CA     C  N S 2   
ALA C      C  N N 3   
ALA O      O  N N 4   
ALA CB     C  N N 5   
ALA OXT    O  N N 6   
ALA H      H  N N 7   
ALA H2     H  N N 8   
ALA HA     H  N N 9   
ALA HB1    H  N N 10  
ALA HB2    H  N N 11  
ALA HB3    H  N N 12  
ALA HXT    H  N N 13  
ARG N      N  N N 14  
ARG CA     C  N S 15  
ARG C      C  N N 16  
ARG O      O  N N 17  
ARG CB     C  N N 18  
ARG CG     C  N N 19  
ARG CD     C  N N 20  
ARG NE     N  N N 21  
ARG CZ     C  N N 22  
ARG NH1    N  N N 23  
ARG NH2    N  N N 24  
ARG OXT    O  N N 25  
ARG H      H  N N 26  
ARG H2     H  N N 27  
ARG HA     H  N N 28  
ARG HB2    H  N N 29  
ARG HB3    H  N N 30  
ARG HG2    H  N N 31  
ARG HG3    H  N N 32  
ARG HD2    H  N N 33  
ARG HD3    H  N N 34  
ARG HE     H  N N 35  
ARG HH11   H  N N 36  
ARG HH12   H  N N 37  
ARG HH21   H  N N 38  
ARG HH22   H  N N 39  
ARG HXT    H  N N 40  
ASN N      N  N N 41  
ASN CA     C  N S 42  
ASN C      C  N N 43  
ASN O      O  N N 44  
ASN CB     C  N N 45  
ASN CG     C  N N 46  
ASN OD1    O  N N 47  
ASN ND2    N  N N 48  
ASN OXT    O  N N 49  
ASN H      H  N N 50  
ASN H2     H  N N 51  
ASN HA     H  N N 52  
ASN HB2    H  N N 53  
ASN HB3    H  N N 54  
ASN HD21   H  N N 55  
ASN HD22   H  N N 56  
ASN HXT    H  N N 57  
ASP N      N  N N 58  
ASP CA     C  N S 59  
ASP C      C  N N 60  
ASP O      O  N N 61  
ASP CB     C  N N 62  
ASP CG     C  N N 63  
ASP OD1    O  N N 64  
ASP OD2    O  N N 65  
ASP OXT    O  N N 66  
ASP H      H  N N 67  
ASP H2     H  N N 68  
ASP HA     H  N N 69  
ASP HB2    H  N N 70  
ASP HB3    H  N N 71  
ASP HD2    H  N N 72  
ASP HXT    H  N N 73  
CA  CA     CA N N 74  
CYS N      N  N N 75  
CYS CA     C  N R 76  
CYS C      C  N N 77  
CYS O      O  N N 78  
CYS CB     C  N N 79  
CYS SG     S  N N 80  
CYS OXT    O  N N 81  
CYS H      H  N N 82  
CYS H2     H  N N 83  
CYS HA     H  N N 84  
CYS HB2    H  N N 85  
CYS HB3    H  N N 86  
CYS HG     H  N N 87  
CYS HXT    H  N N 88  
DA  OP3    O  N N 89  
DA  P      P  N N 90  
DA  OP1    O  N N 91  
DA  OP2    O  N N 92  
DA  "O5'"  O  N N 93  
DA  "C5'"  C  N N 94  
DA  "C4'"  C  N R 95  
DA  "O4'"  O  N N 96  
DA  "C3'"  C  N S 97  
DA  "O3'"  O  N N 98  
DA  "C2'"  C  N N 99  
DA  "C1'"  C  N R 100 
DA  N9     N  Y N 101 
DA  C8     C  Y N 102 
DA  N7     N  Y N 103 
DA  C5     C  Y N 104 
DA  C6     C  Y N 105 
DA  N6     N  N N 106 
DA  N1     N  Y N 107 
DA  C2     C  Y N 108 
DA  N3     N  Y N 109 
DA  C4     C  Y N 110 
DA  HOP3   H  N N 111 
DA  HOP2   H  N N 112 
DA  "H5'"  H  N N 113 
DA  "H5''" H  N N 114 
DA  "H4'"  H  N N 115 
DA  "H3'"  H  N N 116 
DA  "HO3'" H  N N 117 
DA  "H2'"  H  N N 118 
DA  "H2''" H  N N 119 
DA  "H1'"  H  N N 120 
DA  H8     H  N N 121 
DA  H61    H  N N 122 
DA  H62    H  N N 123 
DA  H2     H  N N 124 
DC  OP3    O  N N 125 
DC  P      P  N N 126 
DC  OP1    O  N N 127 
DC  OP2    O  N N 128 
DC  "O5'"  O  N N 129 
DC  "C5'"  C  N N 130 
DC  "C4'"  C  N R 131 
DC  "O4'"  O  N N 132 
DC  "C3'"  C  N S 133 
DC  "O3'"  O  N N 134 
DC  "C2'"  C  N N 135 
DC  "C1'"  C  N R 136 
DC  N1     N  N N 137 
DC  C2     C  N N 138 
DC  O2     O  N N 139 
DC  N3     N  N N 140 
DC  C4     C  N N 141 
DC  N4     N  N N 142 
DC  C5     C  N N 143 
DC  C6     C  N N 144 
DC  HOP3   H  N N 145 
DC  HOP2   H  N N 146 
DC  "H5'"  H  N N 147 
DC  "H5''" H  N N 148 
DC  "H4'"  H  N N 149 
DC  "H3'"  H  N N 150 
DC  "HO3'" H  N N 151 
DC  "H2'"  H  N N 152 
DC  "H2''" H  N N 153 
DC  "H1'"  H  N N 154 
DC  H41    H  N N 155 
DC  H42    H  N N 156 
DC  H5     H  N N 157 
DC  H6     H  N N 158 
DCP N1     N  N N 159 
DCP C2     C  N N 160 
DCP N3     N  N N 161 
DCP C4     C  N N 162 
DCP C5     C  N N 163 
DCP C6     C  N N 164 
DCP O2     O  N N 165 
DCP N4     N  N N 166 
DCP "C1'"  C  N R 167 
DCP "C2'"  C  N N 168 
DCP "C3'"  C  N S 169 
DCP "C4'"  C  N R 170 
DCP "O4'"  O  N N 171 
DCP "O3'"  O  N N 172 
DCP "C5'"  C  N N 173 
DCP "O5'"  O  N N 174 
DCP PA     P  N R 175 
DCP O1A    O  N N 176 
DCP O2A    O  N N 177 
DCP O3A    O  N N 178 
DCP PB     P  N S 179 
DCP O1B    O  N N 180 
DCP O2B    O  N N 181 
DCP O3B    O  N N 182 
DCP PG     P  N N 183 
DCP O1G    O  N N 184 
DCP O2G    O  N N 185 
DCP O3G    O  N N 186 
DCP H5     H  N N 187 
DCP H6     H  N N 188 
DCP HN41   H  N N 189 
DCP HN42   H  N N 190 
DCP "H1'"  H  N N 191 
DCP "H2'1" H  N N 192 
DCP "H2'2" H  N N 193 
DCP "H3'"  H  N N 194 
DCP "H4'"  H  N N 195 
DCP "HO3'" H  N N 196 
DCP "H5'1" H  N N 197 
DCP "H5'2" H  N N 198 
DCP HOA2   H  N N 199 
DCP HOB2   H  N N 200 
DCP HOG2   H  N N 201 
DCP HOG3   H  N N 202 
DG  OP3    O  N N 203 
DG  P      P  N N 204 
DG  OP1    O  N N 205 
DG  OP2    O  N N 206 
DG  "O5'"  O  N N 207 
DG  "C5'"  C  N N 208 
DG  "C4'"  C  N R 209 
DG  "O4'"  O  N N 210 
DG  "C3'"  C  N S 211 
DG  "O3'"  O  N N 212 
DG  "C2'"  C  N N 213 
DG  "C1'"  C  N R 214 
DG  N9     N  Y N 215 
DG  C8     C  Y N 216 
DG  N7     N  Y N 217 
DG  C5     C  Y N 218 
DG  C6     C  N N 219 
DG  O6     O  N N 220 
DG  N1     N  N N 221 
DG  C2     C  N N 222 
DG  N2     N  N N 223 
DG  N3     N  N N 224 
DG  C4     C  Y N 225 
DG  HOP3   H  N N 226 
DG  HOP2   H  N N 227 
DG  "H5'"  H  N N 228 
DG  "H5''" H  N N 229 
DG  "H4'"  H  N N 230 
DG  "H3'"  H  N N 231 
DG  "HO3'" H  N N 232 
DG  "H2'"  H  N N 233 
DG  "H2''" H  N N 234 
DG  "H1'"  H  N N 235 
DG  H8     H  N N 236 
DG  H1     H  N N 237 
DG  H21    H  N N 238 
DG  H22    H  N N 239 
DT  OP3    O  N N 240 
DT  P      P  N N 241 
DT  OP1    O  N N 242 
DT  OP2    O  N N 243 
DT  "O5'"  O  N N 244 
DT  "C5'"  C  N N 245 
DT  "C4'"  C  N R 246 
DT  "O4'"  O  N N 247 
DT  "C3'"  C  N S 248 
DT  "O3'"  O  N N 249 
DT  "C2'"  C  N N 250 
DT  "C1'"  C  N R 251 
DT  N1     N  N N 252 
DT  C2     C  N N 253 
DT  O2     O  N N 254 
DT  N3     N  N N 255 
DT  C4     C  N N 256 
DT  O4     O  N N 257 
DT  C5     C  N N 258 
DT  C7     C  N N 259 
DT  C6     C  N N 260 
DT  HOP3   H  N N 261 
DT  HOP2   H  N N 262 
DT  "H5'"  H  N N 263 
DT  "H5''" H  N N 264 
DT  "H4'"  H  N N 265 
DT  "H3'"  H  N N 266 
DT  "HO3'" H  N N 267 
DT  "H2'"  H  N N 268 
DT  "H2''" H  N N 269 
DT  "H1'"  H  N N 270 
DT  H3     H  N N 271 
DT  H71    H  N N 272 
DT  H72    H  N N 273 
DT  H73    H  N N 274 
DT  H6     H  N N 275 
GLN N      N  N N 276 
GLN CA     C  N S 277 
GLN C      C  N N 278 
GLN O      O  N N 279 
GLN CB     C  N N 280 
GLN CG     C  N N 281 
GLN CD     C  N N 282 
GLN OE1    O  N N 283 
GLN NE2    N  N N 284 
GLN OXT    O  N N 285 
GLN H      H  N N 286 
GLN H2     H  N N 287 
GLN HA     H  N N 288 
GLN HB2    H  N N 289 
GLN HB3    H  N N 290 
GLN HG2    H  N N 291 
GLN HG3    H  N N 292 
GLN HE21   H  N N 293 
GLN HE22   H  N N 294 
GLN HXT    H  N N 295 
GLU N      N  N N 296 
GLU CA     C  N S 297 
GLU C      C  N N 298 
GLU O      O  N N 299 
GLU CB     C  N N 300 
GLU CG     C  N N 301 
GLU CD     C  N N 302 
GLU OE1    O  N N 303 
GLU OE2    O  N N 304 
GLU OXT    O  N N 305 
GLU H      H  N N 306 
GLU H2     H  N N 307 
GLU HA     H  N N 308 
GLU HB2    H  N N 309 
GLU HB3    H  N N 310 
GLU HG2    H  N N 311 
GLU HG3    H  N N 312 
GLU HE2    H  N N 313 
GLU HXT    H  N N 314 
GLY N      N  N N 315 
GLY CA     C  N N 316 
GLY C      C  N N 317 
GLY O      O  N N 318 
GLY OXT    O  N N 319 
GLY H      H  N N 320 
GLY H2     H  N N 321 
GLY HA2    H  N N 322 
GLY HA3    H  N N 323 
GLY HXT    H  N N 324 
HIS N      N  N N 325 
HIS CA     C  N S 326 
HIS C      C  N N 327 
HIS O      O  N N 328 
HIS CB     C  N N 329 
HIS CG     C  Y N 330 
HIS ND1    N  Y N 331 
HIS CD2    C  Y N 332 
HIS CE1    C  Y N 333 
HIS NE2    N  Y N 334 
HIS OXT    O  N N 335 
HIS H      H  N N 336 
HIS H2     H  N N 337 
HIS HA     H  N N 338 
HIS HB2    H  N N 339 
HIS HB3    H  N N 340 
HIS HD1    H  N N 341 
HIS HD2    H  N N 342 
HIS HE1    H  N N 343 
HIS HE2    H  N N 344 
HIS HXT    H  N N 345 
ILE N      N  N N 346 
ILE CA     C  N S 347 
ILE C      C  N N 348 
ILE O      O  N N 349 
ILE CB     C  N S 350 
ILE CG1    C  N N 351 
ILE CG2    C  N N 352 
ILE CD1    C  N N 353 
ILE OXT    O  N N 354 
ILE H      H  N N 355 
ILE H2     H  N N 356 
ILE HA     H  N N 357 
ILE HB     H  N N 358 
ILE HG12   H  N N 359 
ILE HG13   H  N N 360 
ILE HG21   H  N N 361 
ILE HG22   H  N N 362 
ILE HG23   H  N N 363 
ILE HD11   H  N N 364 
ILE HD12   H  N N 365 
ILE HD13   H  N N 366 
ILE HXT    H  N N 367 
LEU N      N  N N 368 
LEU CA     C  N S 369 
LEU C      C  N N 370 
LEU O      O  N N 371 
LEU CB     C  N N 372 
LEU CG     C  N N 373 
LEU CD1    C  N N 374 
LEU CD2    C  N N 375 
LEU OXT    O  N N 376 
LEU H      H  N N 377 
LEU H2     H  N N 378 
LEU HA     H  N N 379 
LEU HB2    H  N N 380 
LEU HB3    H  N N 381 
LEU HG     H  N N 382 
LEU HD11   H  N N 383 
LEU HD12   H  N N 384 
LEU HD13   H  N N 385 
LEU HD21   H  N N 386 
LEU HD22   H  N N 387 
LEU HD23   H  N N 388 
LEU HXT    H  N N 389 
LYS N      N  N N 390 
LYS CA     C  N S 391 
LYS C      C  N N 392 
LYS O      O  N N 393 
LYS CB     C  N N 394 
LYS CG     C  N N 395 
LYS CD     C  N N 396 
LYS CE     C  N N 397 
LYS NZ     N  N N 398 
LYS OXT    O  N N 399 
LYS H      H  N N 400 
LYS H2     H  N N 401 
LYS HA     H  N N 402 
LYS HB2    H  N N 403 
LYS HB3    H  N N 404 
LYS HG2    H  N N 405 
LYS HG3    H  N N 406 
LYS HD2    H  N N 407 
LYS HD3    H  N N 408 
LYS HE2    H  N N 409 
LYS HE3    H  N N 410 
LYS HZ1    H  N N 411 
LYS HZ2    H  N N 412 
LYS HZ3    H  N N 413 
LYS HXT    H  N N 414 
MET N      N  N N 415 
MET CA     C  N S 416 
MET C      C  N N 417 
MET O      O  N N 418 
MET CB     C  N N 419 
MET CG     C  N N 420 
MET SD     S  N N 421 
MET CE     C  N N 422 
MET OXT    O  N N 423 
MET H      H  N N 424 
MET H2     H  N N 425 
MET HA     H  N N 426 
MET HB2    H  N N 427 
MET HB3    H  N N 428 
MET HG2    H  N N 429 
MET HG3    H  N N 430 
MET HE1    H  N N 431 
MET HE2    H  N N 432 
MET HE3    H  N N 433 
MET HXT    H  N N 434 
PHE N      N  N N 435 
PHE CA     C  N S 436 
PHE C      C  N N 437 
PHE O      O  N N 438 
PHE CB     C  N N 439 
PHE CG     C  Y N 440 
PHE CD1    C  Y N 441 
PHE CD2    C  Y N 442 
PHE CE1    C  Y N 443 
PHE CE2    C  Y N 444 
PHE CZ     C  Y N 445 
PHE OXT    O  N N 446 
PHE H      H  N N 447 
PHE H2     H  N N 448 
PHE HA     H  N N 449 
PHE HB2    H  N N 450 
PHE HB3    H  N N 451 
PHE HD1    H  N N 452 
PHE HD2    H  N N 453 
PHE HE1    H  N N 454 
PHE HE2    H  N N 455 
PHE HZ     H  N N 456 
PHE HXT    H  N N 457 
PRO N      N  N N 458 
PRO CA     C  N S 459 
PRO C      C  N N 460 
PRO O      O  N N 461 
PRO CB     C  N N 462 
PRO CG     C  N N 463 
PRO CD     C  N N 464 
PRO OXT    O  N N 465 
PRO H      H  N N 466 
PRO HA     H  N N 467 
PRO HB2    H  N N 468 
PRO HB3    H  N N 469 
PRO HG2    H  N N 470 
PRO HG3    H  N N 471 
PRO HD2    H  N N 472 
PRO HD3    H  N N 473 
PRO HXT    H  N N 474 
SER N      N  N N 475 
SER CA     C  N S 476 
SER C      C  N N 477 
SER O      O  N N 478 
SER CB     C  N N 479 
SER OG     O  N N 480 
SER OXT    O  N N 481 
SER H      H  N N 482 
SER H2     H  N N 483 
SER HA     H  N N 484 
SER HB2    H  N N 485 
SER HB3    H  N N 486 
SER HG     H  N N 487 
SER HXT    H  N N 488 
THR N      N  N N 489 
THR CA     C  N S 490 
THR C      C  N N 491 
THR O      O  N N 492 
THR CB     C  N R 493 
THR OG1    O  N N 494 
THR CG2    C  N N 495 
THR OXT    O  N N 496 
THR H      H  N N 497 
THR H2     H  N N 498 
THR HA     H  N N 499 
THR HB     H  N N 500 
THR HG1    H  N N 501 
THR HG21   H  N N 502 
THR HG22   H  N N 503 
THR HG23   H  N N 504 
THR HXT    H  N N 505 
TRP N      N  N N 506 
TRP CA     C  N S 507 
TRP C      C  N N 508 
TRP O      O  N N 509 
TRP CB     C  N N 510 
TRP CG     C  Y N 511 
TRP CD1    C  Y N 512 
TRP CD2    C  Y N 513 
TRP NE1    N  Y N 514 
TRP CE2    C  Y N 515 
TRP CE3    C  Y N 516 
TRP CZ2    C  Y N 517 
TRP CZ3    C  Y N 518 
TRP CH2    C  Y N 519 
TRP OXT    O  N N 520 
TRP H      H  N N 521 
TRP H2     H  N N 522 
TRP HA     H  N N 523 
TRP HB2    H  N N 524 
TRP HB3    H  N N 525 
TRP HD1    H  N N 526 
TRP HE1    H  N N 527 
TRP HE3    H  N N 528 
TRP HZ2    H  N N 529 
TRP HZ3    H  N N 530 
TRP HH2    H  N N 531 
TRP HXT    H  N N 532 
TYR N      N  N N 533 
TYR CA     C  N S 534 
TYR C      C  N N 535 
TYR O      O  N N 536 
TYR CB     C  N N 537 
TYR CG     C  Y N 538 
TYR CD1    C  Y N 539 
TYR CD2    C  Y N 540 
TYR CE1    C  Y N 541 
TYR CE2    C  Y N 542 
TYR CZ     C  Y N 543 
TYR OH     O  N N 544 
TYR OXT    O  N N 545 
TYR H      H  N N 546 
TYR H2     H  N N 547 
TYR HA     H  N N 548 
TYR HB2    H  N N 549 
TYR HB3    H  N N 550 
TYR HD1    H  N N 551 
TYR HD2    H  N N 552 
TYR HE1    H  N N 553 
TYR HE2    H  N N 554 
TYR HH     H  N N 555 
TYR HXT    H  N N 556 
VAL N      N  N N 557 
VAL CA     C  N S 558 
VAL C      C  N N 559 
VAL O      O  N N 560 
VAL CB     C  N N 561 
VAL CG1    C  N N 562 
VAL CG2    C  N N 563 
VAL OXT    O  N N 564 
VAL H      H  N N 565 
VAL H2     H  N N 566 
VAL HA     H  N N 567 
VAL HB     H  N N 568 
VAL HG11   H  N N 569 
VAL HG12   H  N N 570 
VAL HG13   H  N N 571 
VAL HG21   H  N N 572 
VAL HG22   H  N N 573 
VAL HG23   H  N N 574 
VAL HXT    H  N N 575 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
DA  OP3   P      sing N N 83  
DA  OP3   HOP3   sing N N 84  
DA  P     OP1    doub N N 85  
DA  P     OP2    sing N N 86  
DA  P     "O5'"  sing N N 87  
DA  OP2   HOP2   sing N N 88  
DA  "O5'" "C5'"  sing N N 89  
DA  "C5'" "C4'"  sing N N 90  
DA  "C5'" "H5'"  sing N N 91  
DA  "C5'" "H5''" sing N N 92  
DA  "C4'" "O4'"  sing N N 93  
DA  "C4'" "C3'"  sing N N 94  
DA  "C4'" "H4'"  sing N N 95  
DA  "O4'" "C1'"  sing N N 96  
DA  "C3'" "O3'"  sing N N 97  
DA  "C3'" "C2'"  sing N N 98  
DA  "C3'" "H3'"  sing N N 99  
DA  "O3'" "HO3'" sing N N 100 
DA  "C2'" "C1'"  sing N N 101 
DA  "C2'" "H2'"  sing N N 102 
DA  "C2'" "H2''" sing N N 103 
DA  "C1'" N9     sing N N 104 
DA  "C1'" "H1'"  sing N N 105 
DA  N9    C8     sing Y N 106 
DA  N9    C4     sing Y N 107 
DA  C8    N7     doub Y N 108 
DA  C8    H8     sing N N 109 
DA  N7    C5     sing Y N 110 
DA  C5    C6     sing Y N 111 
DA  C5    C4     doub Y N 112 
DA  C6    N6     sing N N 113 
DA  C6    N1     doub Y N 114 
DA  N6    H61    sing N N 115 
DA  N6    H62    sing N N 116 
DA  N1    C2     sing Y N 117 
DA  C2    N3     doub Y N 118 
DA  C2    H2     sing N N 119 
DA  N3    C4     sing Y N 120 
DC  OP3   P      sing N N 121 
DC  OP3   HOP3   sing N N 122 
DC  P     OP1    doub N N 123 
DC  P     OP2    sing N N 124 
DC  P     "O5'"  sing N N 125 
DC  OP2   HOP2   sing N N 126 
DC  "O5'" "C5'"  sing N N 127 
DC  "C5'" "C4'"  sing N N 128 
DC  "C5'" "H5'"  sing N N 129 
DC  "C5'" "H5''" sing N N 130 
DC  "C4'" "O4'"  sing N N 131 
DC  "C4'" "C3'"  sing N N 132 
DC  "C4'" "H4'"  sing N N 133 
DC  "O4'" "C1'"  sing N N 134 
DC  "C3'" "O3'"  sing N N 135 
DC  "C3'" "C2'"  sing N N 136 
DC  "C3'" "H3'"  sing N N 137 
DC  "O3'" "HO3'" sing N N 138 
DC  "C2'" "C1'"  sing N N 139 
DC  "C2'" "H2'"  sing N N 140 
DC  "C2'" "H2''" sing N N 141 
DC  "C1'" N1     sing N N 142 
DC  "C1'" "H1'"  sing N N 143 
DC  N1    C2     sing N N 144 
DC  N1    C6     sing N N 145 
DC  C2    O2     doub N N 146 
DC  C2    N3     sing N N 147 
DC  N3    C4     doub N N 148 
DC  C4    N4     sing N N 149 
DC  C4    C5     sing N N 150 
DC  N4    H41    sing N N 151 
DC  N4    H42    sing N N 152 
DC  C5    C6     doub N N 153 
DC  C5    H5     sing N N 154 
DC  C6    H6     sing N N 155 
DCP N1    C2     sing N N 156 
DCP N1    C6     sing N N 157 
DCP N1    "C1'"  sing N N 158 
DCP C2    N3     sing N N 159 
DCP C2    O2     doub N N 160 
DCP N3    C4     doub N N 161 
DCP C4    C5     sing N N 162 
DCP C4    N4     sing N N 163 
DCP C5    C6     doub N N 164 
DCP C5    H5     sing N N 165 
DCP C6    H6     sing N N 166 
DCP N4    HN41   sing N N 167 
DCP N4    HN42   sing N N 168 
DCP "C1'" "C2'"  sing N N 169 
DCP "C1'" "O4'"  sing N N 170 
DCP "C1'" "H1'"  sing N N 171 
DCP "C2'" "C3'"  sing N N 172 
DCP "C2'" "H2'1" sing N N 173 
DCP "C2'" "H2'2" sing N N 174 
DCP "C3'" "C4'"  sing N N 175 
DCP "C3'" "O3'"  sing N N 176 
DCP "C3'" "H3'"  sing N N 177 
DCP "C4'" "O4'"  sing N N 178 
DCP "C4'" "C5'"  sing N N 179 
DCP "C4'" "H4'"  sing N N 180 
DCP "O3'" "HO3'" sing N N 181 
DCP "C5'" "O5'"  sing N N 182 
DCP "C5'" "H5'1" sing N N 183 
DCP "C5'" "H5'2" sing N N 184 
DCP "O5'" PA     sing N N 185 
DCP PA    O1A    doub N N 186 
DCP PA    O2A    sing N N 187 
DCP PA    O3A    sing N N 188 
DCP O2A   HOA2   sing N N 189 
DCP O3A   PB     sing N N 190 
DCP PB    O1B    doub N N 191 
DCP PB    O2B    sing N N 192 
DCP PB    O3B    sing N N 193 
DCP O2B   HOB2   sing N N 194 
DCP O3B   PG     sing N N 195 
DCP PG    O1G    doub N N 196 
DCP PG    O2G    sing N N 197 
DCP PG    O3G    sing N N 198 
DCP O2G   HOG2   sing N N 199 
DCP O3G   HOG3   sing N N 200 
DG  OP3   P      sing N N 201 
DG  OP3   HOP3   sing N N 202 
DG  P     OP1    doub N N 203 
DG  P     OP2    sing N N 204 
DG  P     "O5'"  sing N N 205 
DG  OP2   HOP2   sing N N 206 
DG  "O5'" "C5'"  sing N N 207 
DG  "C5'" "C4'"  sing N N 208 
DG  "C5'" "H5'"  sing N N 209 
DG  "C5'" "H5''" sing N N 210 
DG  "C4'" "O4'"  sing N N 211 
DG  "C4'" "C3'"  sing N N 212 
DG  "C4'" "H4'"  sing N N 213 
DG  "O4'" "C1'"  sing N N 214 
DG  "C3'" "O3'"  sing N N 215 
DG  "C3'" "C2'"  sing N N 216 
DG  "C3'" "H3'"  sing N N 217 
DG  "O3'" "HO3'" sing N N 218 
DG  "C2'" "C1'"  sing N N 219 
DG  "C2'" "H2'"  sing N N 220 
DG  "C2'" "H2''" sing N N 221 
DG  "C1'" N9     sing N N 222 
DG  "C1'" "H1'"  sing N N 223 
DG  N9    C8     sing Y N 224 
DG  N9    C4     sing Y N 225 
DG  C8    N7     doub Y N 226 
DG  C8    H8     sing N N 227 
DG  N7    C5     sing Y N 228 
DG  C5    C6     sing N N 229 
DG  C5    C4     doub Y N 230 
DG  C6    O6     doub N N 231 
DG  C6    N1     sing N N 232 
DG  N1    C2     sing N N 233 
DG  N1    H1     sing N N 234 
DG  C2    N2     sing N N 235 
DG  C2    N3     doub N N 236 
DG  N2    H21    sing N N 237 
DG  N2    H22    sing N N 238 
DG  N3    C4     sing N N 239 
DT  OP3   P      sing N N 240 
DT  OP3   HOP3   sing N N 241 
DT  P     OP1    doub N N 242 
DT  P     OP2    sing N N 243 
DT  P     "O5'"  sing N N 244 
DT  OP2   HOP2   sing N N 245 
DT  "O5'" "C5'"  sing N N 246 
DT  "C5'" "C4'"  sing N N 247 
DT  "C5'" "H5'"  sing N N 248 
DT  "C5'" "H5''" sing N N 249 
DT  "C4'" "O4'"  sing N N 250 
DT  "C4'" "C3'"  sing N N 251 
DT  "C4'" "H4'"  sing N N 252 
DT  "O4'" "C1'"  sing N N 253 
DT  "C3'" "O3'"  sing N N 254 
DT  "C3'" "C2'"  sing N N 255 
DT  "C3'" "H3'"  sing N N 256 
DT  "O3'" "HO3'" sing N N 257 
DT  "C2'" "C1'"  sing N N 258 
DT  "C2'" "H2'"  sing N N 259 
DT  "C2'" "H2''" sing N N 260 
DT  "C1'" N1     sing N N 261 
DT  "C1'" "H1'"  sing N N 262 
DT  N1    C2     sing N N 263 
DT  N1    C6     sing N N 264 
DT  C2    O2     doub N N 265 
DT  C2    N3     sing N N 266 
DT  N3    C4     sing N N 267 
DT  N3    H3     sing N N 268 
DT  C4    O4     doub N N 269 
DT  C4    C5     sing N N 270 
DT  C5    C7     sing N N 271 
DT  C5    C6     doub N N 272 
DT  C7    H71    sing N N 273 
DT  C7    H72    sing N N 274 
DT  C7    H73    sing N N 275 
DT  C6    H6     sing N N 276 
GLN N     CA     sing N N 277 
GLN N     H      sing N N 278 
GLN N     H2     sing N N 279 
GLN CA    C      sing N N 280 
GLN CA    CB     sing N N 281 
GLN CA    HA     sing N N 282 
GLN C     O      doub N N 283 
GLN C     OXT    sing N N 284 
GLN CB    CG     sing N N 285 
GLN CB    HB2    sing N N 286 
GLN CB    HB3    sing N N 287 
GLN CG    CD     sing N N 288 
GLN CG    HG2    sing N N 289 
GLN CG    HG3    sing N N 290 
GLN CD    OE1    doub N N 291 
GLN CD    NE2    sing N N 292 
GLN NE2   HE21   sing N N 293 
GLN NE2   HE22   sing N N 294 
GLN OXT   HXT    sing N N 295 
GLU N     CA     sing N N 296 
GLU N     H      sing N N 297 
GLU N     H2     sing N N 298 
GLU CA    C      sing N N 299 
GLU CA    CB     sing N N 300 
GLU CA    HA     sing N N 301 
GLU C     O      doub N N 302 
GLU C     OXT    sing N N 303 
GLU CB    CG     sing N N 304 
GLU CB    HB2    sing N N 305 
GLU CB    HB3    sing N N 306 
GLU CG    CD     sing N N 307 
GLU CG    HG2    sing N N 308 
GLU CG    HG3    sing N N 309 
GLU CD    OE1    doub N N 310 
GLU CD    OE2    sing N N 311 
GLU OE2   HE2    sing N N 312 
GLU OXT   HXT    sing N N 313 
GLY N     CA     sing N N 314 
GLY N     H      sing N N 315 
GLY N     H2     sing N N 316 
GLY CA    C      sing N N 317 
GLY CA    HA2    sing N N 318 
GLY CA    HA3    sing N N 319 
GLY C     O      doub N N 320 
GLY C     OXT    sing N N 321 
GLY OXT   HXT    sing N N 322 
HIS N     CA     sing N N 323 
HIS N     H      sing N N 324 
HIS N     H2     sing N N 325 
HIS CA    C      sing N N 326 
HIS CA    CB     sing N N 327 
HIS CA    HA     sing N N 328 
HIS C     O      doub N N 329 
HIS C     OXT    sing N N 330 
HIS CB    CG     sing N N 331 
HIS CB    HB2    sing N N 332 
HIS CB    HB3    sing N N 333 
HIS CG    ND1    sing Y N 334 
HIS CG    CD2    doub Y N 335 
HIS ND1   CE1    doub Y N 336 
HIS ND1   HD1    sing N N 337 
HIS CD2   NE2    sing Y N 338 
HIS CD2   HD2    sing N N 339 
HIS CE1   NE2    sing Y N 340 
HIS CE1   HE1    sing N N 341 
HIS NE2   HE2    sing N N 342 
HIS OXT   HXT    sing N N 343 
ILE N     CA     sing N N 344 
ILE N     H      sing N N 345 
ILE N     H2     sing N N 346 
ILE CA    C      sing N N 347 
ILE CA    CB     sing N N 348 
ILE CA    HA     sing N N 349 
ILE C     O      doub N N 350 
ILE C     OXT    sing N N 351 
ILE CB    CG1    sing N N 352 
ILE CB    CG2    sing N N 353 
ILE CB    HB     sing N N 354 
ILE CG1   CD1    sing N N 355 
ILE CG1   HG12   sing N N 356 
ILE CG1   HG13   sing N N 357 
ILE CG2   HG21   sing N N 358 
ILE CG2   HG22   sing N N 359 
ILE CG2   HG23   sing N N 360 
ILE CD1   HD11   sing N N 361 
ILE CD1   HD12   sing N N 362 
ILE CD1   HD13   sing N N 363 
ILE OXT   HXT    sing N N 364 
LEU N     CA     sing N N 365 
LEU N     H      sing N N 366 
LEU N     H2     sing N N 367 
LEU CA    C      sing N N 368 
LEU CA    CB     sing N N 369 
LEU CA    HA     sing N N 370 
LEU C     O      doub N N 371 
LEU C     OXT    sing N N 372 
LEU CB    CG     sing N N 373 
LEU CB    HB2    sing N N 374 
LEU CB    HB3    sing N N 375 
LEU CG    CD1    sing N N 376 
LEU CG    CD2    sing N N 377 
LEU CG    HG     sing N N 378 
LEU CD1   HD11   sing N N 379 
LEU CD1   HD12   sing N N 380 
LEU CD1   HD13   sing N N 381 
LEU CD2   HD21   sing N N 382 
LEU CD2   HD22   sing N N 383 
LEU CD2   HD23   sing N N 384 
LEU OXT   HXT    sing N N 385 
LYS N     CA     sing N N 386 
LYS N     H      sing N N 387 
LYS N     H2     sing N N 388 
LYS CA    C      sing N N 389 
LYS CA    CB     sing N N 390 
LYS CA    HA     sing N N 391 
LYS C     O      doub N N 392 
LYS C     OXT    sing N N 393 
LYS CB    CG     sing N N 394 
LYS CB    HB2    sing N N 395 
LYS CB    HB3    sing N N 396 
LYS CG    CD     sing N N 397 
LYS CG    HG2    sing N N 398 
LYS CG    HG3    sing N N 399 
LYS CD    CE     sing N N 400 
LYS CD    HD2    sing N N 401 
LYS CD    HD3    sing N N 402 
LYS CE    NZ     sing N N 403 
LYS CE    HE2    sing N N 404 
LYS CE    HE3    sing N N 405 
LYS NZ    HZ1    sing N N 406 
LYS NZ    HZ2    sing N N 407 
LYS NZ    HZ3    sing N N 408 
LYS OXT   HXT    sing N N 409 
MET N     CA     sing N N 410 
MET N     H      sing N N 411 
MET N     H2     sing N N 412 
MET CA    C      sing N N 413 
MET CA    CB     sing N N 414 
MET CA    HA     sing N N 415 
MET C     O      doub N N 416 
MET C     OXT    sing N N 417 
MET CB    CG     sing N N 418 
MET CB    HB2    sing N N 419 
MET CB    HB3    sing N N 420 
MET CG    SD     sing N N 421 
MET CG    HG2    sing N N 422 
MET CG    HG3    sing N N 423 
MET SD    CE     sing N N 424 
MET CE    HE1    sing N N 425 
MET CE    HE2    sing N N 426 
MET CE    HE3    sing N N 427 
MET OXT   HXT    sing N N 428 
PHE N     CA     sing N N 429 
PHE N     H      sing N N 430 
PHE N     H2     sing N N 431 
PHE CA    C      sing N N 432 
PHE CA    CB     sing N N 433 
PHE CA    HA     sing N N 434 
PHE C     O      doub N N 435 
PHE C     OXT    sing N N 436 
PHE CB    CG     sing N N 437 
PHE CB    HB2    sing N N 438 
PHE CB    HB3    sing N N 439 
PHE CG    CD1    doub Y N 440 
PHE CG    CD2    sing Y N 441 
PHE CD1   CE1    sing Y N 442 
PHE CD1   HD1    sing N N 443 
PHE CD2   CE2    doub Y N 444 
PHE CD2   HD2    sing N N 445 
PHE CE1   CZ     doub Y N 446 
PHE CE1   HE1    sing N N 447 
PHE CE2   CZ     sing Y N 448 
PHE CE2   HE2    sing N N 449 
PHE CZ    HZ     sing N N 450 
PHE OXT   HXT    sing N N 451 
PRO N     CA     sing N N 452 
PRO N     CD     sing N N 453 
PRO N     H      sing N N 454 
PRO CA    C      sing N N 455 
PRO CA    CB     sing N N 456 
PRO CA    HA     sing N N 457 
PRO C     O      doub N N 458 
PRO C     OXT    sing N N 459 
PRO CB    CG     sing N N 460 
PRO CB    HB2    sing N N 461 
PRO CB    HB3    sing N N 462 
PRO CG    CD     sing N N 463 
PRO CG    HG2    sing N N 464 
PRO CG    HG3    sing N N 465 
PRO CD    HD2    sing N N 466 
PRO CD    HD3    sing N N 467 
PRO OXT   HXT    sing N N 468 
SER N     CA     sing N N 469 
SER N     H      sing N N 470 
SER N     H2     sing N N 471 
SER CA    C      sing N N 472 
SER CA    CB     sing N N 473 
SER CA    HA     sing N N 474 
SER C     O      doub N N 475 
SER C     OXT    sing N N 476 
SER CB    OG     sing N N 477 
SER CB    HB2    sing N N 478 
SER CB    HB3    sing N N 479 
SER OG    HG     sing N N 480 
SER OXT   HXT    sing N N 481 
THR N     CA     sing N N 482 
THR N     H      sing N N 483 
THR N     H2     sing N N 484 
THR CA    C      sing N N 485 
THR CA    CB     sing N N 486 
THR CA    HA     sing N N 487 
THR C     O      doub N N 488 
THR C     OXT    sing N N 489 
THR CB    OG1    sing N N 490 
THR CB    CG2    sing N N 491 
THR CB    HB     sing N N 492 
THR OG1   HG1    sing N N 493 
THR CG2   HG21   sing N N 494 
THR CG2   HG22   sing N N 495 
THR CG2   HG23   sing N N 496 
THR OXT   HXT    sing N N 497 
TRP N     CA     sing N N 498 
TRP N     H      sing N N 499 
TRP N     H2     sing N N 500 
TRP CA    C      sing N N 501 
TRP CA    CB     sing N N 502 
TRP CA    HA     sing N N 503 
TRP C     O      doub N N 504 
TRP C     OXT    sing N N 505 
TRP CB    CG     sing N N 506 
TRP CB    HB2    sing N N 507 
TRP CB    HB3    sing N N 508 
TRP CG    CD1    doub Y N 509 
TRP CG    CD2    sing Y N 510 
TRP CD1   NE1    sing Y N 511 
TRP CD1   HD1    sing N N 512 
TRP CD2   CE2    doub Y N 513 
TRP CD2   CE3    sing Y N 514 
TRP NE1   CE2    sing Y N 515 
TRP NE1   HE1    sing N N 516 
TRP CE2   CZ2    sing Y N 517 
TRP CE3   CZ3    doub Y N 518 
TRP CE3   HE3    sing N N 519 
TRP CZ2   CH2    doub Y N 520 
TRP CZ2   HZ2    sing N N 521 
TRP CZ3   CH2    sing Y N 522 
TRP CZ3   HZ3    sing N N 523 
TRP CH2   HH2    sing N N 524 
TRP OXT   HXT    sing N N 525 
TYR N     CA     sing N N 526 
TYR N     H      sing N N 527 
TYR N     H2     sing N N 528 
TYR CA    C      sing N N 529 
TYR CA    CB     sing N N 530 
TYR CA    HA     sing N N 531 
TYR C     O      doub N N 532 
TYR C     OXT    sing N N 533 
TYR CB    CG     sing N N 534 
TYR CB    HB2    sing N N 535 
TYR CB    HB3    sing N N 536 
TYR CG    CD1    doub Y N 537 
TYR CG    CD2    sing Y N 538 
TYR CD1   CE1    sing Y N 539 
TYR CD1   HD1    sing N N 540 
TYR CD2   CE2    doub Y N 541 
TYR CD2   HD2    sing N N 542 
TYR CE1   CZ     doub Y N 543 
TYR CE1   HE1    sing N N 544 
TYR CE2   CZ     sing Y N 545 
TYR CE2   HE2    sing N N 546 
TYR CZ    OH     sing N N 547 
TYR OH    HH     sing N N 548 
TYR OXT   HXT    sing N N 549 
VAL N     CA     sing N N 550 
VAL N     H      sing N N 551 
VAL N     H2     sing N N 552 
VAL CA    C      sing N N 553 
VAL CA    CB     sing N N 554 
VAL CA    HA     sing N N 555 
VAL C     O      doub N N 556 
VAL C     OXT    sing N N 557 
VAL CB    CG1    sing N N 558 
VAL CB    CG2    sing N N 559 
VAL CB    HB     sing N N 560 
VAL CG1   HG11   sing N N 561 
VAL CG1   HG12   sing N N 562 
VAL CG1   HG13   sing N N 563 
VAL CG2   HG21   sing N N 564 
VAL CG2   HG22   sing N N 565 
VAL CG2   HG23   sing N N 566 
VAL OXT   HXT    sing N N 567 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2025-02-14 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9IC3 
_em_admin.last_update        2025-06-04 
_em_admin.map_release_date   2025-06-04 
_em_admin.title              
'Chimeric mitochondrial DNA polymerase gamma ternary complex (hAmB) in mouse-like error-editing conformer (composite)' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 1 2 10090 'Mus musculus' ? ? ? ? ? 
? ? 2 3 9606  'Homo sapiens' ? ? ? ? ? 
? ? 3 4 10090 'Mus musculus' ? ? ? ? ? 
# 
loop_
_em_entity_assembly_recombinant.cell 
_em_entity_assembly_recombinant.entity_assembly_id 
_em_entity_assembly_recombinant.id 
_em_entity_assembly_recombinant.ncbi_tax_id 
_em_entity_assembly_recombinant.organism 
_em_entity_assembly_recombinant.plasmid 
_em_entity_assembly_recombinant.strain 
? 1 2 7108 'Spodoptera frugiperda' ? ? 
? 2 3 7108 'Spodoptera frugiperda' ? ? 
? 3 4 562  'Escherichia coli'      ? ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         40 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'              ? 2  ? ? ? PHENIX 1.20.1_4487: 
'IMAGE ACQUISITION'             ? 3  1 ? 1 ?      ?            
MASKING                         ? 4  1 1 1 ?      ?            
'CTF CORRECTION'                ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'            ? 6  1 1 1 ?      ?            
'DIFFRACTION INDEXING'          ? 7  1 1 1 ?      ?            
'MODEL FITTING'                 ? 8  1 1 1 ?      ?            
OTHER                           ? 9  1 1 1 ?      ?            
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?      ?            
CLASSIFICATION                  ? 12 1 ? ? ?      ?            
RECONSTRUCTION                  ? 13 1 ? ? ?      ?            
'VOLUME SELECTION'              ? 14 1 1 1 ?      ?            
'SERIES ALIGNMENT'              ? 15 1 1 1 ?      ?            
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?      ?            
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?      ?            
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?      ?            
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
9IC3 'double helix'        
9IC3 'a-form double helix' 
9IC3 'b-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 D DG 5  1_555 E DC 36 1_555 -0.171 -0.151 0.389  1.208  -5.228 -0.198 1  P_DG5:DC36_T  P 5  ? T 36 ? 19 1 
1 D DC 6  1_555 E DG 35 1_555 0.177  -0.172 0.523  -2.172 -4.313 0.187  2  P_DC6:DG35_T  P 6  ? T 35 ? 19 1 
1 D DG 7  1_555 E DC 34 1_555 -0.193 -0.153 0.229  -4.337 -3.847 -0.660 3  P_DG7:DC34_T  P 7  ? T 34 ? 19 1 
1 D DG 8  1_555 E DC 33 1_555 -0.212 -0.133 -0.225 -2.757 -2.774 0.667  4  P_DG8:DC33_T  P 8  ? T 33 ? 19 1 
1 D DT 9  1_555 E DA 32 1_555 -0.147 -0.132 0.162  -1.854 -6.633 -1.411 5  P_DT9:DA32_T  P 9  ? T 32 ? 20 1 
1 D DC 10 1_555 E DG 31 1_555 0.212  -0.152 -0.304 -1.292 -3.007 0.966  6  P_DC10:DG31_T P 10 ? T 31 ? 19 1 
1 D DG 11 1_555 E DC 30 1_555 -0.173 -0.222 -0.803 -2.530 -1.207 0.532  7  P_DG11:DC30_T P 11 ? T 30 ? 19 1 
1 D DA 12 1_555 E DT 29 1_555 0.170  -0.183 -0.814 -2.774 -2.072 -3.726 8  P_DA12:DT29_T P 12 ? T 29 ? 20 1 
1 D DG 13 1_555 E DC 28 1_555 -0.175 -0.155 -0.404 -4.178 -2.044 -1.585 9  P_DG13:DC28_T P 13 ? T 28 ? 19 1 
1 D DT 14 1_555 E DA 27 1_555 -0.129 -0.155 0.451  -3.218 -0.751 1.486  10 P_DT14:DA27_T P 14 ? T 27 ? 20 1 
1 D DC 15 1_555 E DG 26 1_555 0.183  -0.191 0.667  -0.158 0.605  -0.020 11 P_DC15:DG26_T P 15 ? T 26 ? 19 1 
1 D DT 16 1_555 E DA 25 1_555 -0.140 -0.304 1.036  2.140  0.654  -0.058 12 P_DT16:DA25_T P 16 ? T 25 ? 20 1 
1 D DA 17 1_555 E DT 24 1_555 0.140  -0.315 1.100  2.532  1.235  -0.548 13 P_DA17:DT24_T P 17 ? T 24 ? 20 1 
1 D DG 18 1_555 E DC 23 1_555 -0.183 -0.284 0.950  0.263  1.260  -0.086 14 P_DG18:DC23_T P 18 ? T 23 ? 19 1 
1 D DA 19 1_555 E DT 22 1_555 0.092  -0.279 0.923  -1.802 3.684  1.060  15 P_DA19:DT22_T P 19 ? T 22 ? 20 1 
1 D DG 20 1_555 E DC 21 1_555 -0.198 -0.138 0.312  0.618  6.777  0.698  16 P_DG20:DC21_T P 20 ? T 21 ? 19 1 
1 D DG 21 1_555 E DC 20 1_555 -0.212 -0.132 -0.168 -2.903 -6.152 0.742  17 P_DG21:DC20_T P 21 ? T 20 ? 19 1 
1 D DA 22 1_555 E DT 19 1_555 0.068  -0.134 -0.180 -4.579 -3.106 2.565  18 P_DA22:DT19_T P 22 ? T 19 ? 20 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 D DG 5  1_555 E DC 36 1_555 D DC 6  1_555 E DG 35 1_555 0.411  0.135  3.807 2.420  -2.191  40.500 0.478  -0.278 3.812 -3.159  
-3.489 40.626 1  PP_DG5DC6:DG35DC36_TT   P 5  ? T 36 ? P 6  ? T 35 ? 
1 D DC 6  1_555 E DG 35 1_555 D DG 7  1_555 E DC 34 1_555 -0.495 1.636  3.662 -0.588 -0.517  39.693 2.477  0.652  3.648 -0.761  
0.867  39.701 2  PP_DC6DG7:DC34DG35_TT   P 6  ? T 35 ? P 7  ? T 34 ? 
1 D DG 7  1_555 E DC 34 1_555 D DG 8  1_555 E DC 33 1_555 -0.461 -0.562 3.414 -1.654 1.995   34.171 -1.280 0.512  3.394 3.389   
2.809  34.267 3  PP_DG7DG8:DC33DC34_TT   P 7  ? T 34 ? P 8  ? T 33 ? 
1 D DG 8  1_555 E DC 33 1_555 D DT 9  1_555 E DA 32 1_555 0.169  -0.492 3.227 -3.218 -0.058  34.769 -0.812 -0.761 3.200 -0.097  
5.370  34.913 4  PP_DG8DT9:DA32DC33_TT   P 8  ? T 33 ? P 9  ? T 32 ? 
1 D DT 9  1_555 E DA 32 1_555 D DC 10 1_555 E DG 31 1_555 0.196  0.130  3.351 0.781  2.791   40.289 -0.133 -0.194 3.355 4.045   
-1.133 40.389 5  PP_DT9DC10:DG31DA32_TT  P 9  ? T 32 ? P 10 ? T 31 ? 
1 D DC 10 1_555 E DG 31 1_555 D DG 11 1_555 E DC 30 1_555 -0.806 0.811  3.935 -2.384 2.571   32.207 0.901  0.931  4.033 4.617   
4.282  32.392 6  PP_DC10DG11:DC30DG31_TT P 10 ? T 31 ? P 11 ? T 30 ? 
1 D DG 11 1_555 E DC 30 1_555 D DA 12 1_555 E DT 29 1_555 -0.310 -0.034 3.261 -0.837 1.554   35.882 -0.277 0.384  3.263 2.521   
1.358  35.924 7  PP_DG11DA12:DT29DC30_TT P 11 ? T 30 ? P 12 ? T 29 ? 
1 D DA 12 1_555 E DT 29 1_555 D DG 13 1_555 E DC 28 1_555 -0.409 -0.795 3.388 -2.694 -0.387  35.020 -1.257 0.259  3.417 -0.642  
4.468  35.123 8  PP_DA12DG13:DC28DT29_TT P 12 ? T 29 ? P 13 ? T 28 ? 
1 D DG 13 1_555 E DC 28 1_555 D DT 14 1_555 E DA 27 1_555 0.833  -0.084 3.398 -2.493 0.486   36.585 -0.203 -1.675 3.335 0.774   
3.966  36.670 9  PP_DG13DT14:DA27DC28_TT P 13 ? T 28 ? P 14 ? T 27 ? 
1 D DT 14 1_555 E DA 27 1_555 D DC 15 1_555 E DG 26 1_555 0.311  -0.644 3.170 -1.958 2.480   33.176 -1.519 -0.856 3.093 4.331   
3.419  33.322 10 PP_DT14DC15:DG26DA27_TT P 14 ? T 27 ? P 15 ? T 26 ? 
1 D DC 15 1_555 E DG 26 1_555 D DT 16 1_555 E DA 25 1_555 0.629  -0.429 3.372 0.163  2.385   32.632 -1.185 -1.087 3.336 4.238   
-0.290 32.717 11 PP_DC15DT16:DA25DG26_TT P 15 ? T 26 ? P 16 ? T 25 ? 
1 D DT 16 1_555 E DA 25 1_555 D DA 17 1_555 E DT 24 1_555 -0.334 -0.045 3.143 -1.368 2.875   36.783 -0.445 0.349  3.141 4.546   
2.163  36.916 12 PP_DT16DA17:DT24DA25_TT P 16 ? T 25 ? P 17 ? T 24 ? 
1 D DA 17 1_555 E DT 24 1_555 D DG 18 1_555 E DC 23 1_555 -0.023 -1.219 3.340 -1.795 0.592   30.621 -2.422 -0.316 3.313 1.119   
3.395  30.678 13 PP_DA17DG18:DC23DT24_TT P 17 ? T 24 ? P 18 ? T 23 ? 
1 D DG 18 1_555 E DC 23 1_555 D DA 19 1_555 E DT 22 1_555 0.280  -0.898 3.397 -0.864 1.099   36.259 -1.600 -0.575 3.362 1.765   
1.388  36.285 14 PP_DG18DA19:DT22DC23_TT P 18 ? T 23 ? P 19 ? T 22 ? 
1 D DA 19 1_555 E DT 22 1_555 D DG 20 1_555 E DC 21 1_555 -1.047 -0.438 3.591 -2.153 3.583   36.502 -1.234 1.339  3.587 5.698   
3.423  36.732 15 PP_DA19DG20:DC21DT22_TT P 19 ? T 22 ? P 20 ? T 21 ? 
1 D DG 20 1_555 E DC 21 1_555 D DG 21 1_555 E DC 20 1_555 0.776  -2.006 3.296 4.870  12.378  27.754 -5.980 -0.602 2.312 24.127  
-9.493 30.720 16 PP_DG20DG21:DC20DC21_TT P 20 ? T 21 ? P 21 ? T 20 ? 
1 D DG 21 1_555 E DC 20 1_555 D DA 22 1_555 E DT 19 1_555 0.482  -1.839 3.661 0.298  -10.292 33.758 -1.198 -0.742 4.036 -17.231 
-0.499 35.249 17 PP_DG21DA22:DT19DC20_TT P 21 ? T 20 ? P 22 ? T 19 ? 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Swedish Research Council'             Sweden ? 1 
Cancerfonden                           Sweden ? 2 
'Knut and Alice Wallenberg Foundation' Sweden ? 3 
# 
_atom_sites.entry_id                    9IC3 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CA 
N  
O  
P  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N     . ARG A 1 52   ? 161.216 105.206 79.070  1.00 42.48  ? 70   ARG A N     1 
ATOM   2     C  CA    . ARG A 1 52   ? 161.490 105.567 80.455  1.00 42.48  ? 70   ARG A CA    1 
ATOM   3     C  C     . ARG A 1 52   ? 162.285 106.862 80.548  1.00 42.48  ? 70   ARG A C     1 
ATOM   4     O  O     . ARG A 1 52   ? 162.711 107.260 81.629  1.00 42.48  ? 70   ARG A O     1 
ATOM   5     C  CB    . ARG A 1 52   ? 162.236 104.438 81.166  1.00 42.48  ? 70   ARG A CB    1 
ATOM   6     C  CG    . ARG A 1 52   ? 161.338 103.307 81.630  1.00 42.48  ? 70   ARG A CG    1 
ATOM   7     C  CD    . ARG A 1 52   ? 162.126 102.228 82.350  1.00 42.48  ? 70   ARG A CD    1 
ATOM   8     N  NE    . ARG A 1 52   ? 161.259 101.379 83.157  1.00 42.48  ? 70   ARG A NE    1 
ATOM   9     C  CZ    . ARG A 1 52   ? 160.605 100.321 82.697  1.00 42.48  ? 70   ARG A CZ    1 
ATOM   10    N  NH1   . ARG A 1 52   ? 160.695 99.949  81.432  1.00 42.48  ? 70   ARG A NH1   1 
ATOM   11    N  NH2   . ARG A 1 52   ? 159.839 99.620  83.529  1.00 42.48  ? 70   ARG A NH2   1 
ATOM   12    N  N     . HIS A 1 53   ? 162.481 107.517 79.408  1.00 46.35  ? 71   HIS A N     1 
ATOM   13    C  CA    . HIS A 1 53   ? 163.132 108.819 79.369  1.00 46.35  ? 71   HIS A CA    1 
ATOM   14    C  C     . HIS A 1 53   ? 162.739 109.512 78.074  1.00 46.35  ? 71   HIS A C     1 
ATOM   15    O  O     . HIS A 1 53   ? 162.259 108.879 77.131  1.00 46.35  ? 71   HIS A O     1 
ATOM   16    C  CB    . HIS A 1 53   ? 164.658 108.704 79.480  1.00 46.35  ? 71   HIS A CB    1 
ATOM   17    C  CG    . HIS A 1 53   ? 165.169 108.753 80.887  1.00 46.35  ? 71   HIS A CG    1 
ATOM   18    N  ND1   . HIS A 1 53   ? 165.041 107.697 81.764  1.00 46.35  ? 71   HIS A ND1   1 
ATOM   19    C  CD2   . HIS A 1 53   ? 165.810 109.732 81.569  1.00 46.35  ? 71   HIS A CD2   1 
ATOM   20    C  CE1   . HIS A 1 53   ? 165.581 108.023 82.925  1.00 46.35  ? 71   HIS A CE1   1 
ATOM   21    N  NE2   . HIS A 1 53   ? 166.054 109.252 82.834  1.00 46.35  ? 71   HIS A NE2   1 
ATOM   22    N  N     . ASN A 1 54   ? 162.952 110.824 78.042  1.00 55.31  ? 72   ASN A N     1 
ATOM   23    C  CA    . ASN A 1 54   ? 162.594 111.624 76.879  1.00 55.31  ? 72   ASN A CA    1 
ATOM   24    C  C     . ASN A 1 54   ? 163.838 112.334 76.358  1.00 55.31  ? 72   ASN A C     1 
ATOM   25    O  O     . ASN A 1 54   ? 164.887 112.293 77.011  1.00 55.31  ? 72   ASN A O     1 
ATOM   26    C  CB    . ASN A 1 54   ? 161.490 112.625 77.235  1.00 55.31  ? 72   ASN A CB    1 
ATOM   27    C  CG    . ASN A 1 54   ? 162.007 113.822 78.006  1.00 55.31  ? 72   ASN A CG    1 
ATOM   28    O  OD1   . ASN A 1 54   ? 162.905 113.700 78.837  1.00 55.31  ? 72   ASN A OD1   1 
ATOM   29    N  ND2   . ASN A 1 54   ? 161.436 114.991 77.734  1.00 55.31  ? 72   ASN A ND2   1 
ATOM   30    N  N     . PRO A 1 55   ? 163.773 112.986 75.184  1.00 64.32  ? 73   PRO A N     1 
ATOM   31    C  CA    . PRO A 1 55   ? 164.932 113.752 74.699  1.00 64.32  ? 73   PRO A CA    1 
ATOM   32    C  C     . PRO A 1 55   ? 165.411 114.841 75.651  1.00 64.32  ? 73   PRO A C     1 
ATOM   33    O  O     . PRO A 1 55   ? 166.441 115.476 75.400  1.00 64.32  ? 73   PRO A O     1 
ATOM   34    C  CB    . PRO A 1 55   ? 164.417 114.353 73.388  1.00 64.32  ? 73   PRO A CB    1 
ATOM   35    C  CG    . PRO A 1 55   ? 163.430 113.360 72.901  1.00 64.32  ? 73   PRO A CG    1 
ATOM   36    C  CD    . PRO A 1 55   ? 162.756 112.813 74.129  1.00 64.32  ? 73   PRO A CD    1 
ATOM   37    N  N     . LEU A 1 56   ? 164.682 115.071 76.744  1.00 61.65  ? 74   LEU A N     1 
ATOM   38    C  CA    . LEU A 1 56   ? 165.071 116.041 77.759  1.00 61.65  ? 74   LEU A CA    1 
ATOM   39    C  C     . LEU A 1 56   ? 165.427 115.377 79.084  1.00 61.65  ? 74   LEU A C     1 
ATOM   40    O  O     . LEU A 1 56   ? 165.485 116.053 80.116  1.00 61.65  ? 74   LEU A O     1 
ATOM   41    C  CB    . LEU A 1 56   ? 163.957 117.066 77.963  1.00 61.65  ? 74   LEU A CB    1 
ATOM   42    C  CG    . LEU A 1 56   ? 163.474 117.760 76.691  1.00 61.65  ? 74   LEU A CG    1 
ATOM   43    C  CD1   . LEU A 1 56   ? 162.278 118.636 76.996  1.00 61.65  ? 74   LEU A CD1   1 
ATOM   44    C  CD2   . LEU A 1 56   ? 164.599 118.571 76.067  1.00 61.65  ? 74   LEU A CD2   1 
ATOM   45    N  N     . ASP A 1 57   ? 165.647 114.061 79.074  1.00 61.44  ? 75   ASP A N     1 
ATOM   46    C  CA    . ASP A 1 57   ? 166.066 113.283 80.239  1.00 61.44  ? 75   ASP A CA    1 
ATOM   47    C  C     . ASP A 1 57   ? 165.028 113.288 81.358  1.00 61.44  ? 75   ASP A C     1 
ATOM   48    O  O     . ASP A 1 57   ? 165.328 112.887 82.487  1.00 61.44  ? 75   ASP A O     1 
ATOM   49    C  CB    . ASP A 1 57   ? 167.420 113.763 80.773  1.00 61.44  ? 75   ASP A CB    1 
ATOM   50    C  CG    . ASP A 1 57   ? 168.519 113.669 79.736  1.00 61.44  ? 75   ASP A CG    1 
ATOM   51    O  OD1   . ASP A 1 57   ? 168.225 113.248 78.598  1.00 61.44  ? 75   ASP A OD1   1 
ATOM   52    O  OD2   . ASP A 1 57   ? 169.674 114.017 80.056  1.00 61.44  ? 75   ASP A OD2   1 
ATOM   53    N  N     . ILE A 1 58   ? 163.810 113.732 81.069  1.00 53.24  ? 76   ILE A N     1 
ATOM   54    C  CA    . ILE A 1 58   ? 162.713 113.639 82.026  1.00 53.24  ? 76   ILE A CA    1 
ATOM   55    C  C     . ILE A 1 58   ? 162.141 112.231 81.948  1.00 53.24  ? 76   ILE A C     1 
ATOM   56    O  O     . ILE A 1 58   ? 161.746 111.772 80.871  1.00 53.24  ? 76   ILE A O     1 
ATOM   57    C  CB    . ILE A 1 58   ? 161.635 114.693 81.739  1.00 53.24  ? 76   ILE A CB    1 
ATOM   58    C  CG1   . ILE A 1 58   ? 162.223 116.097 81.870  1.00 53.24  ? 76   ILE A CG1   1 
ATOM   59    C  CG2   . ILE A 1 58   ? 160.450 114.516 82.674  1.00 53.24  ? 76   ILE A CG2   1 
ATOM   60    C  CD1   . ILE A 1 58   ? 161.234 117.200 81.593  1.00 53.24  ? 76   ILE A CD1   1 
ATOM   61    N  N     . GLN A 1 59   ? 162.104 111.539 83.082  1.00 43.37  ? 77   GLN A N     1 
ATOM   62    C  CA    . GLN A 1 59   ? 161.649 110.153 83.097  1.00 43.37  ? 77   GLN A CA    1 
ATOM   63    C  C     . GLN A 1 59   ? 160.167 110.101 82.761  1.00 43.37  ? 77   GLN A C     1 
ATOM   64    O  O     . GLN A 1 59   ? 159.321 110.486 83.575  1.00 43.37  ? 77   GLN A O     1 
ATOM   65    C  CB    . GLN A 1 59   ? 161.915 109.509 84.452  1.00 43.37  ? 77   GLN A CB    1 
ATOM   66    C  CG    . GLN A 1 59   ? 161.471 108.060 84.507  1.00 43.37  ? 77   GLN A CG    1 
ATOM   67    C  CD    . GLN A 1 59   ? 161.477 107.500 85.906  1.00 43.37  ? 77   GLN A CD    1 
ATOM   68    O  OE1   . GLN A 1 59   ? 161.901 108.165 86.850  1.00 43.37  ? 77   GLN A OE1   1 
ATOM   69    N  NE2   . GLN A 1 59   ? 160.999 106.271 86.053  1.00 43.37  ? 77   GLN A NE2   1 
ATOM   70    N  N     . MET A 1 60   ? 159.851 109.619 81.565  1.00 38.26  ? 78   MET A N     1 
ATOM   71    C  CA    . MET A 1 60   ? 158.469 109.478 81.136  1.00 38.26  ? 78   MET A CA    1 
ATOM   72    C  C     . MET A 1 60   ? 157.863 108.243 81.795  1.00 38.26  ? 78   MET A C     1 
ATOM   73    O  O     . MET A 1 60   ? 158.444 107.634 82.697  1.00 38.26  ? 78   MET A O     1 
ATOM   74    C  CB    . MET A 1 60   ? 158.388 109.417 79.615  1.00 38.26  ? 78   MET A CB    1 
ATOM   75    C  CG    . MET A 1 60   ? 159.161 110.516 78.916  1.00 38.26  ? 78   MET A CG    1 
ATOM   76    S  SD    . MET A 1 60   ? 158.739 112.166 79.500  1.00 38.26  ? 78   MET A SD    1 
ATOM   77    C  CE    . MET A 1 60   ? 157.041 112.297 78.956  1.00 38.26  ? 78   MET A CE    1 
ATOM   78    N  N     . LEU A 1 61   ? 156.673 107.864 81.349  1.00 35.73  ? 79   LEU A N     1 
ATOM   79    C  CA    . LEU A 1 61   ? 155.959 106.755 81.957  1.00 35.73  ? 79   LEU A CA    1 
ATOM   80    C  C     . LEU A 1 61   ? 156.679 105.438 81.687  1.00 35.73  ? 79   LEU A C     1 
ATOM   81    O  O     . LEU A 1 61   ? 157.382 105.281 80.685  1.00 35.73  ? 79   LEU A O     1 
ATOM   82    C  CB    . LEU A 1 61   ? 154.530 106.701 81.417  1.00 35.73  ? 79   LEU A CB    1 
ATOM   83    C  CG    . LEU A 1 61   ? 153.513 105.832 82.146  1.00 35.73  ? 79   LEU A CG    1 
ATOM   84    C  CD1   . LEU A 1 61   ? 153.359 106.312 83.571  1.00 35.73  ? 79   LEU A CD1   1 
ATOM   85    C  CD2   . LEU A 1 61   ? 152.186 105.870 81.418  1.00 35.73  ? 79   LEU A CD2   1 
ATOM   86    N  N     . SER A 1 62   ? 156.501 104.485 82.598  1.00 40.74  ? 80   SER A N     1 
ATOM   87    C  CA    . SER A 1 62   ? 157.104 103.170 82.431  1.00 40.74  ? 80   SER A CA    1 
ATOM   88    C  C     . SER A 1 62   ? 156.465 102.431 81.261  1.00 40.74  ? 80   SER A C     1 
ATOM   89    O  O     . SER A 1 62   ? 155.297 102.646 80.923  1.00 40.74  ? 80   SER A O     1 
ATOM   90    C  CB    . SER A 1 62   ? 156.964 102.349 83.712  1.00 40.74  ? 80   SER A CB    1 
ATOM   91    O  OG    . SER A 1 62   ? 155.608 102.049 83.985  1.00 40.74  ? 80   SER A OG    1 
ATOM   92    N  N     . ARG A 1 63   ? 157.249 101.549 80.637  1.00 48.87  ? 81   ARG A N     1 
ATOM   93    C  CA    . ARG A 1 63   ? 156.776 100.823 79.462  1.00 48.87  ? 81   ARG A CA    1 
ATOM   94    C  C     . ARG A 1 63   ? 155.614 99.890  79.776  1.00 48.87  ? 81   ARG A C     1 
ATOM   95    O  O     . ARG A 1 63   ? 154.869 99.521  78.863  1.00 48.87  ? 81   ARG A O     1 
ATOM   96    C  CB    . ARG A 1 63   ? 157.922 100.024 78.840  1.00 48.87  ? 81   ARG A CB    1 
ATOM   97    C  CG    . ARG A 1 63   ? 159.105 100.874 78.414  1.00 48.87  ? 81   ARG A CG    1 
ATOM   98    C  CD    . ARG A 1 63   ? 160.174 100.042 77.727  1.00 48.87  ? 81   ARG A CD    1 
ATOM   99    N  NE    . ARG A 1 63   ? 161.318 100.859 77.342  1.00 48.87  ? 81   ARG A NE    1 
ATOM   100   C  CZ    . ARG A 1 63   ? 161.427 101.496 76.184  1.00 48.87  ? 81   ARG A CZ    1 
ATOM   101   N  NH1   . ARG A 1 63   ? 160.486 101.413 75.259  1.00 48.87  ? 81   ARG A NH1   1 
ATOM   102   N  NH2   . ARG A 1 63   ? 162.507 102.236 75.950  1.00 48.87  ? 81   ARG A NH2   1 
ATOM   103   N  N     . GLY A 1 64   ? 155.449 99.487  81.036  1.00 47.12  ? 82   GLY A N     1 
ATOM   104   C  CA    . GLY A 1 64   ? 154.319 98.641  81.384  1.00 47.12  ? 82   GLY A CA    1 
ATOM   105   C  C     . GLY A 1 64   ? 152.989 99.344  81.198  1.00 47.12  ? 82   GLY A C     1 
ATOM   106   O  O     . GLY A 1 64   ? 152.004 98.731  80.781  1.00 47.12  ? 82   GLY A O     1 
ATOM   107   N  N     . LEU A 1 65   ? 152.943 100.638 81.507  1.00 42.64  ? 83   LEU A N     1 
ATOM   108   C  CA    . LEU A 1 65   ? 151.731 101.434 81.362  1.00 42.64  ? 83   LEU A CA    1 
ATOM   109   C  C     . LEU A 1 65   ? 151.676 102.164 80.026  1.00 42.64  ? 83   LEU A C     1 
ATOM   110   O  O     . LEU A 1 65   ? 150.604 102.266 79.421  1.00 42.64  ? 83   LEU A O     1 
ATOM   111   C  CB    . LEU A 1 65   ? 151.630 102.444 82.507  1.00 42.64  ? 83   LEU A CB    1 
ATOM   112   C  CG    . LEU A 1 65   ? 151.780 101.895 83.925  1.00 42.64  ? 83   LEU A CG    1 
ATOM   113   C  CD1   . LEU A 1 65   ? 151.745 103.024 84.935  1.00 42.64  ? 83   LEU A CD1   1 
ATOM   114   C  CD2   . LEU A 1 65   ? 150.695 100.879 84.217  1.00 42.64  ? 83   LEU A CD2   1 
ATOM   115   N  N     . HIS A 1 66   ? 152.817 102.681 79.561  1.00 45.11  ? 84   HIS A N     1 
ATOM   116   C  CA    . HIS A 1 66   ? 152.836 103.465 78.331  1.00 45.11  ? 84   HIS A CA    1 
ATOM   117   C  C     . HIS A 1 66   ? 152.409 102.633 77.128  1.00 45.11  ? 84   HIS A C     1 
ATOM   118   O  O     . HIS A 1 66   ? 151.705 103.130 76.242  1.00 45.11  ? 84   HIS A O     1 
ATOM   119   C  CB    . HIS A 1 66   ? 154.228 104.053 78.107  1.00 45.11  ? 84   HIS A CB    1 
ATOM   120   C  CG    . HIS A 1 66   ? 154.318 104.957 76.919  1.00 45.11  ? 84   HIS A CG    1 
ATOM   121   N  ND1   . HIS A 1 66   ? 154.368 104.485 75.625  1.00 45.11  ? 84   HIS A ND1   1 
ATOM   122   C  CD2   . HIS A 1 66   ? 154.374 106.307 76.828  1.00 45.11  ? 84   HIS A CD2   1 
ATOM   123   C  CE1   . HIS A 1 66   ? 154.447 105.504 74.789  1.00 45.11  ? 84   HIS A CE1   1 
ATOM   124   N  NE2   . HIS A 1 66   ? 154.453 106.621 75.493  1.00 45.11  ? 84   HIS A NE2   1 
ATOM   125   N  N     . GLU A 1 67   ? 152.831 101.367 77.072  1.00 55.05  ? 85   GLU A N     1 
ATOM   126   C  CA    . GLU A 1 67   ? 152.469 100.514 75.945  1.00 55.05  ? 85   GLU A CA    1 
ATOM   127   C  C     . GLU A 1 67   ? 150.973 100.236 75.877  1.00 55.05  ? 85   GLU A C     1 
ATOM   128   O  O     . GLU A 1 67   ? 150.480 99.831  74.819  1.00 55.05  ? 85   GLU A O     1 
ATOM   129   C  CB    . GLU A 1 67   ? 153.238 99.192  76.008  1.00 55.05  ? 85   GLU A CB    1 
ATOM   130   C  CG    . GLU A 1 67   ? 154.719 99.321  75.684  1.00 55.05  ? 85   GLU A CG    1 
ATOM   131   C  CD    . GLU A 1 67   ? 155.413 97.976  75.577  1.00 55.05  ? 85   GLU A CD    1 
ATOM   132   O  OE1   . GLU A 1 67   ? 154.715 96.941  75.609  1.00 55.05  ? 85   GLU A OE1   1 
ATOM   133   O  OE2   . GLU A 1 67   ? 156.656 97.955  75.458  1.00 55.05  ? 85   GLU A OE2   1 
ATOM   134   N  N     . GLN A 1 68   ? 150.242 100.436 76.974  1.00 47.58  ? 86   GLN A N     1 
ATOM   135   C  CA    . GLN A 1 68   ? 148.798 100.242 76.992  1.00 47.58  ? 86   GLN A CA    1 
ATOM   136   C  C     . GLN A 1 68   ? 148.039 101.546 77.211  1.00 47.58  ? 86   GLN A C     1 
ATOM   137   O  O     . GLN A 1 68   ? 146.854 101.518 77.553  1.00 47.58  ? 86   GLN A O     1 
ATOM   138   C  CB    . GLN A 1 68   ? 148.411 99.214  78.055  1.00 47.58  ? 86   GLN A CB    1 
ATOM   139   C  CG    . GLN A 1 68   ? 149.085 99.412  79.397  1.00 47.58  ? 86   GLN A CG    1 
ATOM   140   C  CD    . GLN A 1 68   ? 148.710 98.335  80.393  1.00 47.58  ? 86   GLN A CD    1 
ATOM   141   O  OE1   . GLN A 1 68   ? 147.641 97.734  80.301  1.00 47.58  ? 86   GLN A OE1   1 
ATOM   142   N  NE2   . GLN A 1 68   ? 149.594 98.081  81.350  1.00 47.58  ? 86   GLN A NE2   1 
ATOM   143   N  N     . ILE A 1 69   ? 148.699 102.687 77.025  1.00 40.96  ? 87   ILE A N     1 
ATOM   144   C  CA    . ILE A 1 69   ? 148.021 103.976 77.092  1.00 40.96  ? 87   ILE A CA    1 
ATOM   145   C  C     . ILE A 1 69   ? 148.219 104.713 75.775  1.00 40.96  ? 87   ILE A C     1 
ATOM   146   O  O     . ILE A 1 69   ? 147.252 104.997 75.061  1.00 40.96  ? 87   ILE A O     1 
ATOM   147   C  CB    . ILE A 1 69   ? 148.517 104.816 78.283  1.00 40.96  ? 87   ILE A CB    1 
ATOM   148   C  CG1   . ILE A 1 69   ? 147.919 104.289 79.589  1.00 40.96  ? 87   ILE A CG1   1 
ATOM   149   C  CG2   . ILE A 1 69   ? 148.166 106.281 78.090  1.00 40.96  ? 87   ILE A CG2   1 
ATOM   150   C  CD1   . ILE A 1 69   ? 148.206 105.158 80.787  1.00 40.96  ? 87   ILE A CD1   1 
ATOM   151   N  N     . PHE A 1 70   ? 149.470 105.008 75.434  1.00 41.42  ? 88   PHE A N     1 
ATOM   152   C  CA    . PHE A 1 70   ? 149.762 105.751 74.221  1.00 41.42  ? 88   PHE A CA    1 
ATOM   153   C  C     . PHE A 1 70   ? 150.011 104.798 73.055  1.00 41.42  ? 88   PHE A C     1 
ATOM   154   O  O     . PHE A 1 70   ? 149.971 103.573 73.193  1.00 41.42  ? 88   PHE A O     1 
ATOM   155   C  CB    . PHE A 1 70   ? 150.949 106.685 74.444  1.00 41.42  ? 88   PHE A CB    1 
ATOM   156   C  CG    . PHE A 1 70   ? 150.666 107.797 75.410  1.00 41.42  ? 88   PHE A CG    1 
ATOM   157   C  CD1   . PHE A 1 70   ? 149.913 108.889 75.025  1.00 41.42  ? 88   PHE A CD1   1 
ATOM   158   C  CD2   . PHE A 1 70   ? 151.151 107.748 76.704  1.00 41.42  ? 88   PHE A CD2   1 
ATOM   159   C  CE1   . PHE A 1 70   ? 149.650 109.913 75.908  1.00 41.42  ? 88   PHE A CE1   1 
ATOM   160   C  CE2   . PHE A 1 70   ? 150.891 108.769 77.593  1.00 41.42  ? 88   PHE A CE2   1 
ATOM   161   C  CZ    . PHE A 1 70   ? 150.139 109.853 77.193  1.00 41.42  ? 88   PHE A CZ    1 
ATOM   162   N  N     . GLY A 1 71   ? 150.270 105.374 71.883  1.00 56.78  ? 89   GLY A N     1 
ATOM   163   C  CA    . GLY A 1 71   ? 150.418 104.574 70.685  1.00 56.78  ? 89   GLY A CA    1 
ATOM   164   C  C     . GLY A 1 71   ? 151.759 103.868 70.617  1.00 56.78  ? 89   GLY A C     1 
ATOM   165   O  O     . GLY A 1 71   ? 152.779 104.360 71.099  1.00 56.78  ? 89   GLY A O     1 
ATOM   166   N  N     . GLN A 1 72   ? 151.742 102.682 70.007  1.00 65.31  ? 90   GLN A N     1 
ATOM   167   C  CA    . GLN A 1 72   ? 152.975 101.932 69.799  1.00 65.31  ? 90   GLN A CA    1 
ATOM   168   C  C     . GLN A 1 72   ? 153.925 102.696 68.886  1.00 65.31  ? 90   GLN A C     1 
ATOM   169   O  O     . GLN A 1 72   ? 155.028 103.080 69.292  1.00 65.31  ? 90   GLN A O     1 
ATOM   170   C  CB    . GLN A 1 72   ? 152.656 100.553 69.220  1.00 65.31  ? 90   GLN A CB    1 
ATOM   171   C  CG    . GLN A 1 72   ? 153.884 99.713  68.919  1.00 65.31  ? 90   GLN A CG    1 
ATOM   172   C  CD    . GLN A 1 72   ? 153.535 98.394  68.261  1.00 65.31  ? 90   GLN A CD    1 
ATOM   173   O  OE1   . GLN A 1 72   ? 152.368 98.111  67.993  1.00 65.31  ? 90   GLN A OE1   1 
ATOM   174   N  NE2   . GLN A 1 72   ? 154.549 97.579  67.995  1.00 65.31  ? 90   GLN A NE2   1 
ATOM   175   N  N     . GLY A 1 73   ? 153.512 102.923 67.638  1.00 63.21  ? 91   GLY A N     1 
ATOM   176   C  CA    . GLY A 1 73   ? 154.322 103.735 66.745  1.00 63.21  ? 91   GLY A CA    1 
ATOM   177   C  C     . GLY A 1 73   ? 154.399 105.181 67.197  1.00 63.21  ? 91   GLY A C     1 
ATOM   178   O  O     . GLY A 1 73   ? 155.488 105.751 67.312  1.00 63.21  ? 91   GLY A O     1 
ATOM   179   N  N     . GLY A 1 74   ? 153.245 105.783 67.476  1.00 67.11  ? 92   GLY A N     1 
ATOM   180   C  CA    . GLY A 1 74   ? 153.215 107.152 67.967  1.00 67.11  ? 92   GLY A CA    1 
ATOM   181   C  C     . GLY A 1 74   ? 153.901 108.109 67.018  1.00 67.11  ? 92   GLY A C     1 
ATOM   182   O  O     . GLY A 1 74   ? 153.679 108.083 65.801  1.00 67.11  ? 92   GLY A O     1 
ATOM   183   N  N     . GLU A 1 75   ? 154.750 108.968 67.576  1.00 78.50  ? 93   GLU A N     1 
ATOM   184   C  CA    . GLU A 1 75   ? 155.545 109.896 66.787  1.00 78.50  ? 93   GLU A CA    1 
ATOM   185   C  C     . GLU A 1 75   ? 156.692 110.403 67.648  1.00 78.50  ? 93   GLU A C     1 
ATOM   186   O  O     . GLU A 1 75   ? 156.499 110.713 68.826  1.00 78.50  ? 93   GLU A O     1 
ATOM   187   C  CB    . GLU A 1 75   ? 154.701 111.069 66.273  1.00 78.50  ? 93   GLU A CB    1 
ATOM   188   C  CG    . GLU A 1 75   ? 155.490 112.109 65.492  1.00 78.50  ? 93   GLU A CG    1 
ATOM   189   C  CD    . GLU A 1 75   ? 156.187 111.526 64.277  1.00 78.50  ? 93   GLU A CD    1 
ATOM   190   O  OE1   . GLU A 1 75   ? 155.621 110.611 63.643  1.00 78.50  ? 93   GLU A OE1   1 
ATOM   191   O  OE2   . GLU A 1 75   ? 157.305 111.982 63.957  1.00 78.50  ? 93   GLU A OE2   1 
ATOM   192   N  N     . MET A 1 76   ? 157.879 110.481 67.053  1.00 85.69  ? 94   MET A N     1 
ATOM   193   C  CA    . MET A 1 76   ? 159.054 110.959 67.768  1.00 85.69  ? 94   MET A CA    1 
ATOM   194   C  C     . MET A 1 76   ? 159.378 112.378 67.339  1.00 85.69  ? 94   MET A C     1 
ATOM   195   O  O     . MET A 1 76   ? 159.305 112.687 66.141  1.00 85.69  ? 94   MET A O     1 
ATOM   196   C  CB    . MET A 1 76   ? 160.250 110.050 67.501  1.00 85.69  ? 94   MET A CB    1 
ATOM   197   C  CG    . MET A 1 76   ? 160.031 108.610 67.933  1.00 85.69  ? 94   MET A CG    1 
ATOM   198   S  SD    . MET A 1 76   ? 161.413 107.533 67.510  1.00 85.69  ? 94   MET A SD    1 
ATOM   199   C  CE    . MET A 1 76   ? 160.846 105.977 68.190  1.00 85.69  ? 94   MET A CE    1 
ATOM   200   N  N     . PRO A 1 77   ? 159.718 113.265 68.273  1.00 81.60  ? 95   PRO A N     1 
ATOM   201   C  CA    . PRO A 1 77   ? 160.033 114.647 67.895  1.00 81.60  ? 95   PRO A CA    1 
ATOM   202   C  C     . PRO A 1 77   ? 161.245 114.708 66.978  1.00 81.60  ? 95   PRO A C     1 
ATOM   203   O  O     . PRO A 1 77   ? 162.184 113.919 67.102  1.00 81.60  ? 95   PRO A O     1 
ATOM   204   C  CB    . PRO A 1 77   ? 160.306 115.330 69.240  1.00 81.60  ? 95   PRO A CB    1 
ATOM   205   C  CG    . PRO A 1 77   ? 159.622 114.470 70.253  1.00 81.60  ? 95   PRO A CG    1 
ATOM   206   C  CD    . PRO A 1 77   ? 159.741 113.071 69.732  1.00 81.60  ? 95   PRO A CD    1 
ATOM   207   N  N     . GLY A 1 78   ? 161.216 115.661 66.054  1.00 73.99  ? 96   GLY A N     1 
ATOM   208   C  CA    . GLY A 1 78   ? 162.299 115.813 65.108  1.00 73.99  ? 96   GLY A CA    1 
ATOM   209   C  C     . GLY A 1 78   ? 163.554 116.365 65.754  1.00 73.99  ? 96   GLY A C     1 
ATOM   210   O  O     . GLY A 1 78   ? 163.563 116.829 66.894  1.00 73.99  ? 96   GLY A O     1 
ATOM   211   N  N     . GLU A 1 79   ? 164.648 116.303 64.991  1.00 72.50  ? 97   GLU A N     1 
ATOM   212   C  CA    . GLU A 1 79   ? 165.924 116.810 65.486  1.00 72.50  ? 97   GLU A CA    1 
ATOM   213   C  C     . GLU A 1 79   ? 165.863 118.312 65.736  1.00 72.50  ? 97   GLU A C     1 
ATOM   214   O  O     . GLU A 1 79   ? 166.393 118.803 66.738  1.00 72.50  ? 97   GLU A O     1 
ATOM   215   C  CB    . GLU A 1 79   ? 167.042 116.475 64.500  1.00 72.50  ? 97   GLU A CB    1 
ATOM   216   C  CG    . GLU A 1 79   ? 168.385 117.099 64.849  1.00 72.50  ? 97   GLU A CG    1 
ATOM   217   C  CD    . GLU A 1 79   ? 168.911 116.644 66.198  1.00 72.50  ? 97   GLU A CD    1 
ATOM   218   O  OE1   . GLU A 1 79   ? 168.657 115.482 66.578  1.00 72.50  ? 97   GLU A OE1   1 
ATOM   219   O  OE2   . GLU A 1 79   ? 169.575 117.452 66.880  1.00 72.50  ? 97   GLU A OE2   1 
ATOM   220   N  N     . ALA A 1 80   ? 165.223 119.058 64.833  1.00 68.08  ? 98   ALA A N     1 
ATOM   221   C  CA    . ALA A 1 80   ? 165.105 120.501 65.018  1.00 68.08  ? 98   ALA A CA    1 
ATOM   222   C  C     . ALA A 1 80   ? 164.257 120.837 66.238  1.00 68.08  ? 98   ALA A C     1 
ATOM   223   O  O     . ALA A 1 80   ? 164.595 121.745 67.007  1.00 68.08  ? 98   ALA A O     1 
ATOM   224   C  CB    . ALA A 1 80   ? 164.519 121.146 63.763  1.00 68.08  ? 98   ALA A CB    1 
ATOM   225   N  N     . ALA A 1 81   ? 163.149 120.118 66.432  1.00 66.17  ? 99   ALA A N     1 
ATOM   226   C  CA    . ALA A 1 81   ? 162.286 120.376 67.582  1.00 66.17  ? 99   ALA A CA    1 
ATOM   227   C  C     . ALA A 1 81   ? 163.013 120.091 68.890  1.00 66.17  ? 99   ALA A C     1 
ATOM   228   O  O     . ALA A 1 81   ? 162.955 120.887 69.836  1.00 66.17  ? 99   ALA A O     1 
ATOM   229   C  CB    . ALA A 1 81   ? 161.012 119.539 67.478  1.00 66.17  ? 99   ALA A CB    1 
ATOM   230   N  N     . VAL A 1 82   ? 163.708 118.954 68.960  1.00 64.54  ? 100  VAL A N     1 
ATOM   231   C  CA    . VAL A 1 82   ? 164.443 118.607 70.171  1.00 64.54  ? 100  VAL A CA    1 
ATOM   232   C  C     . VAL A 1 82   ? 165.570 119.600 70.412  1.00 64.54  ? 100  VAL A C     1 
ATOM   233   O  O     . VAL A 1 82   ? 165.837 119.989 71.554  1.00 64.54  ? 100  VAL A O     1 
ATOM   234   C  CB    . VAL A 1 82   ? 164.966 117.162 70.080  1.00 64.54  ? 100  VAL A CB    1 
ATOM   235   C  CG1   . VAL A 1 82   ? 165.888 116.856 71.247  1.00 64.54  ? 100  VAL A CG1   1 
ATOM   236   C  CG2   . VAL A 1 82   ? 163.806 116.182 70.049  1.00 64.54  ? 100  VAL A CG2   1 
ATOM   237   N  N     . ARG A 1 83   ? 166.245 120.030 69.345  1.00 68.43  ? 101  ARG A N     1 
ATOM   238   C  CA    . ARG A 1 83   ? 167.316 121.010 69.490  1.00 68.43  ? 101  ARG A CA    1 
ATOM   239   C  C     . ARG A 1 83   ? 166.782 122.333 70.025  1.00 68.43  ? 101  ARG A C     1 
ATOM   240   O  O     . ARG A 1 83   ? 167.391 122.943 70.912  1.00 68.43  ? 101  ARG A O     1 
ATOM   241   C  CB    . ARG A 1 83   ? 168.019 121.207 68.146  1.00 68.43  ? 101  ARG A CB    1 
ATOM   242   C  CG    . ARG A 1 83   ? 169.228 122.130 68.183  1.00 68.43  ? 101  ARG A CG    1 
ATOM   243   C  CD    . ARG A 1 83   ? 168.877 123.532 67.706  1.00 68.43  ? 101  ARG A CD    1 
ATOM   244   N  NE    . ARG A 1 83   ? 168.213 123.516 66.409  1.00 68.43  ? 101  ARG A NE    1 
ATOM   245   C  CZ    . ARG A 1 83   ? 168.844 123.544 65.242  1.00 68.43  ? 101  ARG A CZ    1 
ATOM   246   N  NH1   . ARG A 1 83   ? 170.164 123.590 65.171  1.00 68.43  ? 101  ARG A NH1   1 
ATOM   247   N  NH2   . ARG A 1 83   ? 168.131 123.526 64.119  1.00 68.43  ? 101  ARG A NH2   1 
ATOM   248   N  N     . ARG A 1 84   ? 165.640 122.788 69.503  1.00 65.32  ? 102  ARG A N     1 
ATOM   249   C  CA    . ARG A 1 84   ? 165.043 124.027 69.990  1.00 65.32  ? 102  ARG A CA    1 
ATOM   250   C  C     . ARG A 1 84   ? 164.611 123.897 71.445  1.00 65.32  ? 102  ARG A C     1 
ATOM   251   O  O     . ARG A 1 84   ? 164.797 124.825 72.243  1.00 65.32  ? 102  ARG A O     1 
ATOM   252   C  CB    . ARG A 1 84   ? 163.857 124.415 69.106  1.00 65.32  ? 102  ARG A CB    1 
ATOM   253   C  CG    . ARG A 1 84   ? 163.183 125.720 69.499  1.00 65.32  ? 102  ARG A CG    1 
ATOM   254   C  CD    . ARG A 1 84   ? 162.061 126.088 68.537  1.00 65.32  ? 102  ARG A CD    1 
ATOM   255   N  NE    . ARG A 1 84   ? 160.976 125.114 68.543  1.00 65.32  ? 102  ARG A NE    1 
ATOM   256   C  CZ    . ARG A 1 84   ? 160.799 124.180 67.619  1.00 65.32  ? 102  ARG A CZ    1 
ATOM   257   N  NH1   . ARG A 1 84   ? 161.622 124.061 66.589  1.00 65.32  ? 102  ARG A NH1   1 
ATOM   258   N  NH2   . ARG A 1 84   ? 159.770 123.344 67.729  1.00 65.32  ? 102  ARG A NH2   1 
ATOM   259   N  N     . SER A 1 85   ? 164.032 122.750 71.811  1.00 61.97  ? 103  SER A N     1 
ATOM   260   C  CA    . SER A 1 85   ? 163.633 122.532 73.198  1.00 61.97  ? 103  SER A CA    1 
ATOM   261   C  C     . SER A 1 85   ? 164.838 122.536 74.131  1.00 61.97  ? 103  SER A C     1 
ATOM   262   O  O     . SER A 1 85   ? 164.790 123.124 75.219  1.00 61.97  ? 103  SER A O     1 
ATOM   263   C  CB    . SER A 1 85   ? 162.869 121.217 73.318  1.00 61.97  ? 103  SER A CB    1 
ATOM   264   O  OG    . SER A 1 85   ? 162.757 120.825 74.672  1.00 61.97  ? 103  SER A OG    1 
ATOM   265   N  N     . VAL A 1 86   ? 165.926 121.881 73.724  1.00 67.13  ? 104  VAL A N     1 
ATOM   266   C  CA    . VAL A 1 86   ? 167.133 121.853 74.545  1.00 67.13  ? 104  VAL A CA    1 
ATOM   267   C  C     . VAL A 1 86   ? 167.722 123.252 74.674  1.00 67.13  ? 104  VAL A C     1 
ATOM   268   O  O     . VAL A 1 86   ? 168.192 123.644 75.747  1.00 67.13  ? 104  VAL A O     1 
ATOM   269   C  CB    . VAL A 1 86   ? 168.153 120.854 73.965  1.00 67.13  ? 104  VAL A CB    1 
ATOM   270   C  CG1   . VAL A 1 86   ? 169.499 121.000 74.656  1.00 67.13  ? 104  VAL A CG1   1 
ATOM   271   C  CG2   . VAL A 1 86   ? 167.639 119.431 74.113  1.00 67.13  ? 104  VAL A CG2   1 
ATOM   272   N  N     . GLU A 1 87   ? 167.709 124.025 73.585  1.00 67.73  ? 105  GLU A N     1 
ATOM   273   C  CA    . GLU A 1 87   ? 168.189 125.401 73.656  1.00 67.73  ? 105  GLU A CA    1 
ATOM   274   C  C     . GLU A 1 87   ? 167.351 126.229 74.620  1.00 67.73  ? 105  GLU A C     1 
ATOM   275   O  O     . GLU A 1 87   ? 167.892 127.015 75.408  1.00 67.73  ? 105  GLU A O     1 
ATOM   276   C  CB    . GLU A 1 87   ? 168.186 126.035 72.266  1.00 67.73  ? 105  GLU A CB    1 
ATOM   277   C  CG    . GLU A 1 87   ? 169.292 125.540 71.353  1.00 67.73  ? 105  GLU A CG    1 
ATOM   278   C  CD    . GLU A 1 87   ? 169.302 126.251 70.014  1.00 67.73  ? 105  GLU A CD    1 
ATOM   279   O  OE1   . GLU A 1 87   ? 168.281 126.882 69.667  1.00 67.73  ? 105  GLU A OE1   1 
ATOM   280   O  OE2   . GLU A 1 87   ? 170.331 126.183 69.311  1.00 67.73  ? 105  GLU A OE2   1 
ATOM   281   N  N     . HIS A 1 88   ? 166.026 126.069 74.573  1.00 64.03  ? 106  HIS A N     1 
ATOM   282   C  CA    . HIS A 1 88   ? 165.161 126.811 75.484  1.00 64.03  ? 106  HIS A CA    1 
ATOM   283   C  C     . HIS A 1 88   ? 165.417 126.418 76.934  1.00 64.03  ? 106  HIS A C     1 
ATOM   284   O  O     . HIS A 1 88   ? 165.464 127.280 77.819  1.00 64.03  ? 106  HIS A O     1 
ATOM   285   C  CB    . HIS A 1 88   ? 163.695 126.586 75.120  1.00 64.03  ? 106  HIS A CB    1 
ATOM   286   C  CG    . HIS A 1 88   ? 162.733 127.277 76.036  1.00 64.03  ? 106  HIS A CG    1 
ATOM   287   N  ND1   . HIS A 1 88   ? 162.644 128.649 76.126  1.00 64.03  ? 106  HIS A ND1   1 
ATOM   288   C  CD2   . HIS A 1 88   ? 161.818 126.784 76.904  1.00 64.03  ? 106  HIS A CD2   1 
ATOM   289   C  CE1   . HIS A 1 88   ? 161.716 128.972 77.009  1.00 64.03  ? 106  HIS A CE1   1 
ATOM   290   N  NE2   . HIS A 1 88   ? 161.200 127.858 77.496  1.00 64.03  ? 106  HIS A NE2   1 
ATOM   291   N  N     . LEU A 1 89   ? 165.578 125.119 77.197  1.00 67.12  ? 107  LEU A N     1 
ATOM   292   C  CA    . LEU A 1 89   ? 165.850 124.670 78.559  1.00 67.12  ? 107  LEU A CA    1 
ATOM   293   C  C     . LEU A 1 89   ? 167.201 125.171 79.056  1.00 67.12  ? 107  LEU A C     1 
ATOM   294   O  O     . LEU A 1 89   ? 167.327 125.585 80.215  1.00 67.12  ? 107  LEU A O     1 
ATOM   295   C  CB    . LEU A 1 89   ? 165.782 123.145 78.632  1.00 67.12  ? 107  LEU A CB    1 
ATOM   296   C  CG    . LEU A 1 89   ? 164.399 122.550 78.884  1.00 67.12  ? 107  LEU A CG    1 
ATOM   297   C  CD1   . LEU A 1 89   ? 164.459 121.034 78.867  1.00 67.12  ? 107  LEU A CD1   1 
ATOM   298   C  CD2   . LEU A 1 89   ? 163.855 123.049 80.209  1.00 67.12  ? 107  LEU A CD2   1 
ATOM   299   N  N     . GLN A 1 90   ? 168.222 125.144 78.197  1.00 71.12  ? 108  GLN A N     1 
ATOM   300   C  CA    . GLN A 1 90   ? 169.557 125.572 78.595  1.00 71.12  ? 108  GLN A CA    1 
ATOM   301   C  C     . GLN A 1 90   ? 169.668 127.085 78.718  1.00 71.12  ? 108  GLN A C     1 
ATOM   302   O  O     . GLN A 1 90   ? 170.550 127.574 79.433  1.00 71.12  ? 108  GLN A O     1 
ATOM   303   C  CB    . GLN A 1 90   ? 170.586 125.046 77.592  1.00 71.12  ? 108  GLN A CB    1 
ATOM   304   C  CG    . GLN A 1 90   ? 172.031 125.179 78.037  1.00 71.12  ? 108  GLN A CG    1 
ATOM   305   C  CD    . GLN A 1 90   ? 173.002 124.615 77.021  1.00 71.12  ? 108  GLN A CD    1 
ATOM   306   O  OE1   . GLN A 1 90   ? 172.604 124.166 75.947  1.00 71.12  ? 108  GLN A OE1   1 
ATOM   307   N  NE2   . GLN A 1 90   ? 174.286 124.633 77.358  1.00 71.12  ? 108  GLN A NE2   1 
ATOM   308   N  N     . LYS A 1 91   ? 168.796 127.835 78.040  1.00 67.88  ? 109  LYS A N     1 
ATOM   309   C  CA    . LYS A 1 91   ? 168.823 129.289 78.156  1.00 67.88  ? 109  LYS A CA    1 
ATOM   310   C  C     . LYS A 1 91   ? 168.523 129.733 79.582  1.00 67.88  ? 109  LYS A C     1 
ATOM   311   O  O     . LYS A 1 91   ? 169.131 130.685 80.085  1.00 67.88  ? 109  LYS A O     1 
ATOM   312   C  CB    . LYS A 1 91   ? 167.825 129.905 77.175  1.00 67.88  ? 109  LYS A CB    1 
ATOM   313   C  CG    . LYS A 1 91   ? 167.703 131.416 77.266  1.00 67.88  ? 109  LYS A CG    1 
ATOM   314   C  CD    . LYS A 1 91   ? 166.730 131.947 76.226  1.00 67.88  ? 109  LYS A CD    1 
ATOM   315   C  CE    . LYS A 1 91   ? 166.478 133.433 76.413  1.00 67.88  ? 109  LYS A CE    1 
ATOM   316   N  NZ    . LYS A 1 91   ? 165.839 133.722 77.727  1.00 67.88  ? 109  LYS A NZ    1 
ATOM   317   N  N     . HIS A 1 92   ? 167.594 129.054 80.248  1.00 67.74  ? 110  HIS A N     1 
ATOM   318   C  CA    . HIS A 1 92   ? 167.239 129.362 81.626  1.00 67.74  ? 110  HIS A CA    1 
ATOM   319   C  C     . HIS A 1 92   ? 168.062 128.578 82.640  1.00 67.74  ? 110  HIS A C     1 
ATOM   320   O  O     . HIS A 1 92   ? 167.862 128.753 83.846  1.00 67.74  ? 110  HIS A O     1 
ATOM   321   C  CB    . HIS A 1 92   ? 165.748 129.097 81.856  1.00 67.74  ? 110  HIS A CB    1 
ATOM   322   C  CG    . HIS A 1 92   ? 164.848 129.919 80.986  1.00 67.74  ? 110  HIS A CG    1 
ATOM   323   N  ND1   . HIS A 1 92   ? 164.239 131.074 81.425  1.00 67.74  ? 110  HIS A ND1   1 
ATOM   324   C  CD2   . HIS A 1 92   ? 164.459 129.754 79.699  1.00 67.74  ? 110  HIS A CD2   1 
ATOM   325   C  CE1   . HIS A 1 92   ? 163.512 131.585 80.448  1.00 67.74  ? 110  HIS A CE1   1 
ATOM   326   N  NE2   . HIS A 1 92   ? 163.628 130.804 79.390  1.00 67.74  ? 110  HIS A NE2   1 
ATOM   327   N  N     . GLY A 1 93   ? 168.974 127.721 82.186  1.00 69.07  ? 111  GLY A N     1 
ATOM   328   C  CA    . GLY A 1 93   ? 169.795 126.941 83.088  1.00 69.07  ? 111  GLY A CA    1 
ATOM   329   C  C     . GLY A 1 93   ? 169.150 125.685 83.626  1.00 69.07  ? 111  GLY A C     1 
ATOM   330   O  O     . GLY A 1 93   ? 169.756 125.010 84.466  1.00 69.07  ? 111  GLY A O     1 
ATOM   331   N  N     . LEU A 1 94   ? 167.943 125.348 83.175  1.00 70.33  ? 112  LEU A N     1 
ATOM   332   C  CA    . LEU A 1 94   ? 167.254 124.156 83.652  1.00 70.33  ? 112  LEU A CA    1 
ATOM   333   C  C     . LEU A 1 94   ? 167.726 122.880 82.971  1.00 70.33  ? 112  LEU A C     1 
ATOM   334   O  O     . LEU A 1 94   ? 167.424 121.788 83.465  1.00 70.33  ? 112  LEU A O     1 
ATOM   335   C  CB    . LEU A 1 94   ? 165.745 124.308 83.454  1.00 70.33  ? 112  LEU A CB    1 
ATOM   336   C  CG    . LEU A 1 94   ? 165.079 125.466 84.194  1.00 70.33  ? 112  LEU A CG    1 
ATOM   337   C  CD1   . LEU A 1 94   ? 163.604 125.541 83.848  1.00 70.33  ? 112  LEU A CD1   1 
ATOM   338   C  CD2   . LEU A 1 94   ? 165.273 125.314 85.692  1.00 70.33  ? 112  LEU A CD2   1 
ATOM   339   N  N     . TRP A 1 95   ? 168.449 122.983 81.860  1.00 73.89  ? 113  TRP A N     1 
ATOM   340   C  CA    . TRP A 1 95   ? 168.940 121.812 81.148  1.00 73.89  ? 113  TRP A CA    1 
ATOM   341   C  C     . TRP A 1 95   ? 170.278 121.380 81.732  1.00 73.89  ? 113  TRP A C     1 
ATOM   342   O  O     . TRP A 1 95   ? 171.220 122.176 81.802  1.00 73.89  ? 113  TRP A O     1 
ATOM   343   C  CB    . TRP A 1 95   ? 169.075 122.102 79.653  1.00 73.89  ? 113  TRP A CB    1 
ATOM   344   C  CG    . TRP A 1 95   ? 169.673 120.975 78.867  1.00 73.89  ? 113  TRP A CG    1 
ATOM   345   C  CD1   . TRP A 1 95   ? 170.779 121.030 78.072  1.00 73.89  ? 113  TRP A CD1   1 
ATOM   346   C  CD2   . TRP A 1 95   ? 169.204 119.621 78.806  1.00 73.89  ? 113  TRP A CD2   1 
ATOM   347   N  NE1   . TRP A 1 95   ? 171.025 119.799 77.515  1.00 73.89  ? 113  TRP A NE1   1 
ATOM   348   C  CE2   . TRP A 1 95   ? 170.073 118.917 77.951  1.00 73.89  ? 113  TRP A CE2   1 
ATOM   349   C  CE3   . TRP A 1 95   ? 168.132 118.938 79.389  1.00 73.89  ? 113  TRP A CE3   1 
ATOM   350   C  CZ2   . TRP A 1 95   ? 169.904 117.564 77.665  1.00 73.89  ? 113  TRP A CZ2   1 
ATOM   351   C  CZ3   . TRP A 1 95   ? 167.968 117.597 79.106  1.00 73.89  ? 113  TRP A CZ3   1 
ATOM   352   C  CH2   . TRP A 1 95   ? 168.848 116.924 78.251  1.00 73.89  ? 113  TRP A CH2   1 
ATOM   353   N  N     . GLY A 1 96   ? 170.354 120.122 82.145  1.00 74.00  ? 114  GLY A N     1 
ATOM   354   C  CA    . GLY A 1 96   ? 171.518 119.598 82.814  1.00 74.00  ? 114  GLY A CA    1 
ATOM   355   C  C     . GLY A 1 96   ? 171.388 119.461 84.314  1.00 74.00  ? 114  GLY A C     1 
ATOM   356   O  O     . GLY A 1 96   ? 172.406 119.519 85.012  1.00 74.00  ? 114  GLY A O     1 
ATOM   357   N  N     . GLN A 1 97   ? 170.174 119.282 84.831  1.00 70.56  ? 115  GLN A N     1 
ATOM   358   C  CA    . GLN A 1 97   ? 169.930 119.116 86.264  1.00 70.56  ? 115  GLN A CA    1 
ATOM   359   C  C     . GLN A 1 97   ? 169.095 117.860 86.474  1.00 70.56  ? 115  GLN A C     1 
ATOM   360   O  O     . GLN A 1 97   ? 167.915 117.935 86.838  1.00 70.56  ? 115  GLN A O     1 
ATOM   361   C  CB    . GLN A 1 97   ? 169.228 120.341 86.852  1.00 70.56  ? 115  GLN A CB    1 
ATOM   362   C  CG    . GLN A 1 97   ? 169.604 121.665 86.202  1.00 70.56  ? 115  GLN A CG    1 
ATOM   363   C  CD    . GLN A 1 97   ? 171.054 122.048 86.430  1.00 70.56  ? 115  GLN A CD    1 
ATOM   364   O  OE1   . GLN A 1 97   ? 171.680 121.613 87.396  1.00 70.56  ? 115  GLN A OE1   1 
ATOM   365   N  NE2   . GLN A 1 97   ? 171.595 122.869 85.538  1.00 70.56  ? 115  GLN A NE2   1 
ATOM   366   N  N     . PRO A 1 98   ? 169.676 116.683 86.249  1.00 62.22  ? 116  PRO A N     1 
ATOM   367   C  CA    . PRO A 1 98   ? 168.904 115.446 86.392  1.00 62.22  ? 116  PRO A CA    1 
ATOM   368   C  C     . PRO A 1 98   ? 168.477 115.212 87.831  1.00 62.22  ? 116  PRO A C     1 
ATOM   369   O  O     . PRO A 1 98   ? 169.161 115.600 88.781  1.00 62.22  ? 116  PRO A O     1 
ATOM   370   C  CB    . PRO A 1 98   ? 169.878 114.363 85.917  1.00 62.22  ? 116  PRO A CB    1 
ATOM   371   C  CG    . PRO A 1 98   ? 171.224 114.938 86.183  1.00 62.22  ? 116  PRO A CG    1 
ATOM   372   C  CD    . PRO A 1 98   ? 171.093 116.417 85.944  1.00 62.22  ? 116  PRO A CD    1 
ATOM   373   N  N     . ALA A 1 99   ? 167.326 114.566 87.981  1.00 57.63  ? 117  ALA A N     1 
ATOM   374   C  CA    . ALA A 1 99   ? 166.761 114.251 89.281  1.00 57.63  ? 117  ALA A CA    1 
ATOM   375   C  C     . ALA A 1 99   ? 166.708 112.741 89.464  1.00 57.63  ? 117  ALA A C     1 
ATOM   376   O  O     . ALA A 1 99   ? 166.734 111.975 88.497  1.00 57.63  ? 117  ALA A O     1 
ATOM   377   C  CB    . ALA A 1 99   ? 165.358 114.852 89.442  1.00 57.63  ? 117  ALA A CB    1 
ATOM   378   N  N     . VAL A 1 100  ? 166.645 112.322 90.722  1.00 55.70  ? 118  VAL A N     1 
ATOM   379   C  CA    . VAL A 1 100  ? 166.613 110.888 91.032  1.00 55.70  ? 118  VAL A CA    1 
ATOM   380   C  C     . VAL A 1 100  ? 165.338 110.279 90.461  1.00 55.70  ? 118  VAL A C     1 
ATOM   381   O  O     . VAL A 1 100  ? 164.285 110.942 90.458  1.00 55.70  ? 118  VAL A O     1 
ATOM   382   C  CB    . VAL A 1 100  ? 166.706 110.665 92.544  1.00 55.70  ? 118  VAL A CB    1 
ATOM   383   C  CG1   . VAL A 1 100  ? 168.072 111.095 93.056  1.00 55.70  ? 118  VAL A CG1   1 
ATOM   384   C  CG2   . VAL A 1 100  ? 165.603 111.422 93.268  1.00 55.70  ? 118  VAL A CG2   1 
ATOM   385   N  N     . PRO A 1 101  ? 165.377 109.047 89.960  1.00 53.48  ? 119  PRO A N     1 
ATOM   386   C  CA    . PRO A 1 101  ? 164.177 108.463 89.353  1.00 53.48  ? 119  PRO A CA    1 
ATOM   387   C  C     . PRO A 1 101  ? 163.263 107.840 90.394  1.00 53.48  ? 119  PRO A C     1 
ATOM   388   O  O     . PRO A 1 101  ? 163.713 107.217 91.358  1.00 53.48  ? 119  PRO A O     1 
ATOM   389   C  CB    . PRO A 1 101  ? 164.750 107.398 88.411  1.00 53.48  ? 119  PRO A CB    1 
ATOM   390   C  CG    . PRO A 1 101  ? 166.002 106.962 89.090  1.00 53.48  ? 119  PRO A CG    1 
ATOM   391   C  CD    . PRO A 1 101  ? 166.556 108.177 89.801  1.00 53.48  ? 119  PRO A CD    1 
ATOM   392   N  N     . LEU A 1 102  ? 161.963 108.025 90.194  1.00 50.10  ? 120  LEU A N     1 
ATOM   393   C  CA    . LEU A 1 102  ? 160.991 107.343 91.025  1.00 50.10  ? 120  LEU A CA    1 
ATOM   394   C  C     . LEU A 1 102  ? 160.998 105.851 90.704  1.00 50.10  ? 120  LEU A C     1 
ATOM   395   O  O     . LEU A 1 102  ? 161.282 105.455 89.570  1.00 50.10  ? 120  LEU A O     1 
ATOM   396   C  CB    . LEU A 1 102  ? 159.589 107.910 90.805  1.00 50.10  ? 120  LEU A CB    1 
ATOM   397   C  CG    . LEU A 1 102  ? 159.323 109.382 91.132  1.00 50.10  ? 120  LEU A CG    1 
ATOM   398   C  CD1   . LEU A 1 102  ? 159.581 110.277 89.927  1.00 50.10  ? 120  LEU A CD1   1 
ATOM   399   C  CD2   . LEU A 1 102  ? 157.906 109.564 91.646  1.00 50.10  ? 120  LEU A CD2   1 
ATOM   400   N  N     . PRO A 1 103  ? 160.711 105.000 91.688  1.00 52.78  ? 121  PRO A N     1 
ATOM   401   C  CA    . PRO A 1 103  ? 160.567 103.571 91.395  1.00 52.78  ? 121  PRO A CA    1 
ATOM   402   C  C     . PRO A 1 103  ? 159.469 103.346 90.368  1.00 52.78  ? 121  PRO A C     1 
ATOM   403   O  O     . PRO A 1 103  ? 158.408 103.972 90.416  1.00 52.78  ? 121  PRO A O     1 
ATOM   404   C  CB    . PRO A 1 103  ? 160.206 102.965 92.754  1.00 52.78  ? 121  PRO A CB    1 
ATOM   405   C  CG    . PRO A 1 103  ? 160.760 103.924 93.748  1.00 52.78  ? 121  PRO A CG    1 
ATOM   406   C  CD    . PRO A 1 103  ? 160.617 105.283 93.129  1.00 52.78  ? 121  PRO A CD    1 
ATOM   407   N  N     . ASP A 1 104  ? 159.733 102.443 89.431  1.00 55.18  ? 122  ASP A N     1 
ATOM   408   C  CA    . ASP A 1 104  ? 158.802 102.223 88.336  1.00 55.18  ? 122  ASP A CA    1 
ATOM   409   C  C     . ASP A 1 104  ? 157.569 101.467 88.814  1.00 55.18  ? 122  ASP A C     1 
ATOM   410   O  O     . ASP A 1 104  ? 157.604 100.725 89.799  1.00 55.18  ? 122  ASP A O     1 
ATOM   411   C  CB    . ASP A 1 104  ? 159.482 101.466 87.197  1.00 55.18  ? 122  ASP A CB    1 
ATOM   412   C  CG    . ASP A 1 104  ? 160.437 102.341 86.412  1.00 55.18  ? 122  ASP A CG    1 
ATOM   413   O  OD1   . ASP A 1 104  ? 160.594 103.526 86.777  1.00 55.18  ? 122  ASP A OD1   1 
ATOM   414   O  OD2   . ASP A 1 104  ? 161.027 101.847 85.429  1.00 55.18  ? 122  ASP A OD2   1 
ATOM   415   N  N     . VAL A 1 105  ? 156.470 101.667 88.095  1.00 48.42  ? 123  VAL A N     1 
ATOM   416   C  CA    . VAL A 1 105  ? 155.167 101.121 88.448  1.00 48.42  ? 123  VAL A CA    1 
ATOM   417   C  C     . VAL A 1 105  ? 154.742 100.158 87.350  1.00 48.42  ? 123  VAL A C     1 
ATOM   418   O  O     . VAL A 1 105  ? 154.804 100.497 86.163  1.00 48.42  ? 123  VAL A O     1 
ATOM   419   C  CB    . VAL A 1 105  ? 154.124 102.239 88.634  1.00 48.42  ? 123  VAL A CB    1 
ATOM   420   C  CG1   . VAL A 1 105  ? 152.720 101.669 88.629  1.00 48.42  ? 123  VAL A CG1   1 
ATOM   421   C  CG2   . VAL A 1 105  ? 154.389 103.004 89.921  1.00 48.42  ? 123  VAL A CG2   1 
ATOM   422   N  N     . GLU A 1 106  ? 154.323 98.959  87.745  1.00 51.30  ? 124  GLU A N     1 
ATOM   423   C  CA    . GLU A 1 106  ? 153.835 97.943  86.817  1.00 51.30  ? 124  GLU A CA    1 
ATOM   424   C  C     . GLU A 1 106  ? 152.401 97.602  87.198  1.00 51.30  ? 124  GLU A C     1 
ATOM   425   O  O     . GLU A 1 106  ? 152.167 96.892  88.182  1.00 51.30  ? 124  GLU A O     1 
ATOM   426   C  CB    . GLU A 1 106  ? 154.722 96.697  86.842  1.00 51.30  ? 124  GLU A CB    1 
ATOM   427   C  CG    . GLU A 1 106  ? 156.152 96.925  86.362  1.00 51.30  ? 124  GLU A CG    1 
ATOM   428   C  CD    . GLU A 1 106  ? 156.244 97.187  84.867  1.00 51.30  ? 124  GLU A CD    1 
ATOM   429   O  OE1   . GLU A 1 106  ? 155.263 96.909  84.146  1.00 51.30  ? 124  GLU A OE1   1 
ATOM   430   O  OE2   . GLU A 1 106  ? 157.302 97.670  84.412  1.00 51.30  ? 124  GLU A OE2   1 
ATOM   431   N  N     . LEU A 1 107  ? 151.446 98.104  86.421  1.00 46.23  ? 125  LEU A N     1 
ATOM   432   C  CA    . LEU A 1 107  ? 150.033 97.861  86.662  1.00 46.23  ? 125  LEU A CA    1 
ATOM   433   C  C     . LEU A 1 107  ? 149.389 97.286  85.410  1.00 46.23  ? 125  LEU A C     1 
ATOM   434   O  O     . LEU A 1 107  ? 149.788 97.600  84.286  1.00 46.23  ? 125  LEU A O     1 
ATOM   435   C  CB    . LEU A 1 107  ? 149.295 99.145  87.068  1.00 46.23  ? 125  LEU A CB    1 
ATOM   436   C  CG    . LEU A 1 107  ? 149.618 99.800  88.409  1.00 46.23  ? 125  LEU A CG    1 
ATOM   437   C  CD1   . LEU A 1 107  ? 149.039 101.201 88.454  1.00 46.23  ? 125  LEU A CD1   1 
ATOM   438   C  CD2   . LEU A 1 107  ? 149.071 98.969  89.550  1.00 46.23  ? 125  LEU A CD2   1 
ATOM   439   N  N     . ARG A 1 108  ? 148.386 96.438  85.620  1.00 53.41  ? 126  ARG A N     1 
ATOM   440   C  CA    . ARG A 1 108  ? 147.538 95.945  84.536  1.00 53.41  ? 126  ARG A CA    1 
ATOM   441   C  C     . ARG A 1 108  ? 146.318 96.853  84.473  1.00 53.41  ? 126  ARG A C     1 
ATOM   442   O  O     . ARG A 1 108  ? 145.295 96.603  85.112  1.00 53.41  ? 126  ARG A O     1 
ATOM   443   C  CB    . ARG A 1 108  ? 147.152 94.489  84.761  1.00 53.41  ? 126  ARG A CB    1 
ATOM   444   C  CG    . ARG A 1 108  ? 148.200 93.478  84.323  1.00 53.41  ? 126  ARG A CG    1 
ATOM   445   C  CD    . ARG A 1 108  ? 148.266 93.363  82.806  1.00 53.41  ? 126  ARG A CD    1 
ATOM   446   N  NE    . ARG A 1 108  ? 149.247 94.266  82.217  1.00 53.41  ? 126  ARG A NE    1 
ATOM   447   C  CZ    . ARG A 1 108  ? 149.452 94.398  80.913  1.00 53.41  ? 126  ARG A CZ    1 
ATOM   448   N  NH1   . ARG A 1 108  ? 148.742 93.716  80.030  1.00 53.41  ? 126  ARG A NH1   1 
ATOM   449   N  NH2   . ARG A 1 108  ? 150.392 95.236  80.485  1.00 53.41  ? 126  ARG A NH2   1 
ATOM   450   N  N     . LEU A 1 109  ? 146.435 97.926  83.696  1.00 45.15  ? 127  LEU A N     1 
ATOM   451   C  CA    . LEU A 1 109  ? 145.365 98.903  83.603  1.00 45.15  ? 127  LEU A CA    1 
ATOM   452   C  C     . LEU A 1 109  ? 144.122 98.274  82.977  1.00 45.15  ? 127  LEU A C     1 
ATOM   453   O  O     . LEU A 1 109  ? 144.223 97.307  82.217  1.00 45.15  ? 127  LEU A O     1 
ATOM   454   C  CB    . LEU A 1 109  ? 145.808 100.103 82.773  1.00 45.15  ? 127  LEU A CB    1 
ATOM   455   C  CG    . LEU A 1 109  ? 147.024 100.869 83.285  1.00 45.15  ? 127  LEU A CG    1 
ATOM   456   C  CD1   . LEU A 1 109  ? 147.360 102.001 82.343  1.00 45.15  ? 127  LEU A CD1   1 
ATOM   457   C  CD2   . LEU A 1 109  ? 146.765 101.393 84.682  1.00 45.15  ? 127  LEU A CD2   1 
ATOM   458   N  N     . PRO A 1 110  ? 142.938 98.790  83.299  1.00 43.34  ? 128  PRO A N     1 
ATOM   459   C  CA    . PRO A 1 110  ? 141.734 98.301  82.641  1.00 43.34  ? 128  PRO A CA    1 
ATOM   460   C  C     . PRO A 1 110  ? 141.819 98.533  81.145  1.00 43.34  ? 128  PRO A C     1 
ATOM   461   O  O     . PRO A 1 110  ? 142.398 99.535  80.687  1.00 43.34  ? 128  PRO A O     1 
ATOM   462   C  CB    . PRO A 1 110  ? 140.617 99.136  83.280  1.00 43.34  ? 128  PRO A CB    1 
ATOM   463   C  CG    . PRO A 1 110  ? 141.173 99.567  84.588  1.00 43.34  ? 128  PRO A CG    1 
ATOM   464   C  CD    . PRO A 1 110  ? 142.634 99.775  84.350  1.00 43.34  ? 128  PRO A CD    1 
ATOM   465   N  N     . PRO A 1 111  ? 141.266 97.623  80.344  1.00 46.09  ? 129  PRO A N     1 
ATOM   466   C  CA    . PRO A 1 111  ? 141.399 97.750  78.886  1.00 46.09  ? 129  PRO A CA    1 
ATOM   467   C  C     . PRO A 1 111  ? 140.737 99.008  78.352  1.00 46.09  ? 129  PRO A C     1 
ATOM   468   O  O     . PRO A 1 111  ? 139.512 99.150  78.417  1.00 46.09  ? 129  PRO A O     1 
ATOM   469   C  CB    . PRO A 1 111  ? 140.711 96.483  78.361  1.00 46.09  ? 129  PRO A CB    1 
ATOM   470   C  CG    . PRO A 1 111  ? 139.774 96.081  79.455  1.00 46.09  ? 129  PRO A CG    1 
ATOM   471   C  CD    . PRO A 1 111  ? 140.468 96.449  80.730  1.00 46.09  ? 129  PRO A CD    1 
ATOM   472   N  N     . LEU A 1 112  ? 141.541 99.930  77.827  1.00 47.07  ? 130  LEU A N     1 
ATOM   473   C  CA    . LEU A 1 112  ? 141.003 101.178 77.304  1.00 47.07  ? 130  LEU A CA    1 
ATOM   474   C  C     . LEU A 1 112  ? 140.158 100.905 76.067  1.00 47.07  ? 130  LEU A C     1 
ATOM   475   O  O     . LEU A 1 112  ? 140.587 100.193 75.153  1.00 47.07  ? 130  LEU A O     1 
ATOM   476   C  CB    . LEU A 1 112  ? 142.135 102.149 76.971  1.00 47.07  ? 130  LEU A CB    1 
ATOM   477   C  CG    . LEU A 1 112  ? 143.134 102.484 78.082  1.00 47.07  ? 130  LEU A CG    1 
ATOM   478   C  CD1   . LEU A 1 112  ? 143.966 103.698 77.700  1.00 47.07  ? 130  LEU A CD1   1 
ATOM   479   C  CD2   . LEU A 1 112  ? 142.430 102.707 79.410  1.00 47.07  ? 130  LEU A CD2   1 
ATOM   480   N  N     . TYR A 1 113  ? 138.956 101.472 76.038  1.00 50.03  ? 131  TYR A N     1 
ATOM   481   C  CA    . TYR A 1 113  ? 138.055 101.273 74.916  1.00 50.03  ? 131  TYR A CA    1 
ATOM   482   C  C     . TYR A 1 113  ? 138.496 102.110 73.719  1.00 50.03  ? 131  TYR A C     1 
ATOM   483   O  O     . TYR A 1 113  ? 139.305 103.035 73.831  1.00 50.03  ? 131  TYR A O     1 
ATOM   484   C  CB    . TYR A 1 113  ? 136.621 101.620 75.310  1.00 50.03  ? 131  TYR A CB    1 
ATOM   485   C  CG    . TYR A 1 113  ? 136.073 100.755 76.419  1.00 50.03  ? 131  TYR A CG    1 
ATOM   486   C  CD1   . TYR A 1 113  ? 135.870 99.397  76.227  1.00 50.03  ? 131  TYR A CD1   1 
ATOM   487   C  CD2   . TYR A 1 113  ? 135.755 101.296 77.656  1.00 50.03  ? 131  TYR A CD2   1 
ATOM   488   C  CE1   . TYR A 1 113  ? 135.370 98.600  77.238  1.00 50.03  ? 131  TYR A CE1   1 
ATOM   489   C  CE2   . TYR A 1 113  ? 135.253 100.507 78.672  1.00 50.03  ? 131  TYR A CE2   1 
ATOM   490   C  CZ    . TYR A 1 113  ? 135.063 99.160  78.458  1.00 50.03  ? 131  TYR A CZ    1 
ATOM   491   O  OH    . TYR A 1 113  ? 134.564 98.371  79.467  1.00 50.03  ? 131  TYR A OH    1 
ATOM   492   N  N     . GLY A 1 114  ? 137.949 101.770 72.553  1.00 54.38  ? 132  GLY A N     1 
ATOM   493   C  CA    . GLY A 1 114  ? 138.307 102.485 71.346  1.00 54.38  ? 132  GLY A CA    1 
ATOM   494   C  C     . GLY A 1 114  ? 139.748 102.227 70.940  1.00 54.38  ? 132  GLY A C     1 
ATOM   495   O  O     . GLY A 1 114  ? 140.353 101.207 71.284  1.00 54.38  ? 132  GLY A O     1 
ATOM   496   N  N     . ASP A 1 115  ? 140.306 103.177 70.192  1.00 56.05  ? 133  ASP A N     1 
ATOM   497   C  CA    . ASP A 1 115  ? 141.684 103.092 69.721  1.00 56.05  ? 133  ASP A CA    1 
ATOM   498   C  C     . ASP A 1 115  ? 142.637 103.887 70.607  1.00 56.05  ? 133  ASP A C     1 
ATOM   499   O  O     . ASP A 1 115  ? 143.619 103.341 71.117  1.00 56.05  ? 133  ASP A O     1 
ATOM   500   C  CB    . ASP A 1 115  ? 141.772 103.581 68.270  1.00 56.05  ? 133  ASP A CB    1 
ATOM   501   C  CG    . ASP A 1 115  ? 141.135 102.615 67.293  1.00 56.05  ? 133  ASP A CG    1 
ATOM   502   O  OD1   . ASP A 1 115  ? 140.881 101.455 67.679  1.00 56.05  ? 133  ASP A OD1   1 
ATOM   503   O  OD2   . ASP A 1 115  ? 140.893 103.017 66.135  1.00 56.05  ? 133  ASP A OD2   1 
ATOM   504   N  N     . ASN A 1 116  ? 142.365 105.173 70.796  1.00 45.96  ? 134  ASN A N     1 
ATOM   505   C  CA    . ASN A 1 116  ? 143.200 106.055 71.593  1.00 45.96  ? 134  ASN A CA    1 
ATOM   506   C  C     . ASN A 1 116  ? 142.482 106.428 72.888  1.00 45.96  ? 134  ASN A C     1 
ATOM   507   O  O     . ASN A 1 116  ? 141.413 105.897 73.212  1.00 45.96  ? 134  ASN A O     1 
ATOM   508   C  CB    . ASN A 1 116  ? 143.586 107.290 70.775  1.00 45.96  ? 134  ASN A CB    1 
ATOM   509   C  CG    . ASN A 1 116  ? 142.396 107.936 70.097  1.00 45.96  ? 134  ASN A CG    1 
ATOM   510   O  OD1   . ASN A 1 116  ? 141.252 107.727 70.495  1.00 45.96  ? 134  ASN A OD1   1 
ATOM   511   N  ND2   . ASN A 1 116  ? 142.661 108.724 69.064  1.00 45.96  ? 134  ASN A ND2   1 
ATOM   512   N  N     . LEU A 1 117  ? 143.098 107.333 73.651  1.00 40.92  ? 135  LEU A N     1 
ATOM   513   C  CA    . LEU A 1 117  ? 142.466 107.846 74.862  1.00 40.92  ? 135  LEU A CA    1 
ATOM   514   C  C     . LEU A 1 117  ? 141.202 108.630 74.539  1.00 40.92  ? 135  LEU A C     1 
ATOM   515   O  O     . LEU A 1 117  ? 140.208 108.545 75.271  1.00 40.92  ? 135  LEU A O     1 
ATOM   516   C  CB    . LEU A 1 117  ? 143.450 108.725 75.630  1.00 40.92  ? 135  LEU A CB    1 
ATOM   517   C  CG    . LEU A 1 117  ? 144.597 108.033 76.360  1.00 40.92  ? 135  LEU A CG    1 
ATOM   518   C  CD1   . LEU A 1 117  ? 145.785 108.964 76.435  1.00 40.92  ? 135  LEU A CD1   1 
ATOM   519   C  CD2   . LEU A 1 117  ? 144.154 107.617 77.751  1.00 40.92  ? 135  LEU A CD2   1 
ATOM   520   N  N     . ASP A 1 118  ? 141.230 109.413 73.459  1.00 39.48  ? 136  ASP A N     1 
ATOM   521   C  CA    . ASP A 1 118  ? 140.105 110.284 73.137  1.00 39.48  ? 136  ASP A CA    1 
ATOM   522   C  C     . ASP A 1 118  ? 138.842 109.479 72.868  1.00 39.48  ? 136  ASP A C     1 
ATOM   523   O  O     . ASP A 1 118  ? 137.765 109.808 73.377  1.00 39.48  ? 136  ASP A O     1 
ATOM   524   C  CB    . ASP A 1 118  ? 140.454 111.160 71.934  1.00 39.48  ? 136  ASP A CB    1 
ATOM   525   C  CG    . ASP A 1 118  ? 139.521 112.341 71.784  1.00 39.48  ? 136  ASP A CG    1 
ATOM   526   O  OD1   . ASP A 1 118  ? 138.627 112.509 72.640  1.00 39.48  ? 136  ASP A OD1   1 
ATOM   527   O  OD2   . ASP A 1 118  ? 139.684 113.108 70.813  1.00 39.48  ? 136  ASP A OD2   1 
ATOM   528   N  N     . GLN A 1 119  ? 138.953 108.410 72.077  1.00 41.76  ? 137  GLN A N     1 
ATOM   529   C  CA    . GLN A 1 119  ? 137.788 107.573 71.812  1.00 41.76  ? 137  GLN A CA    1 
ATOM   530   C  C     . GLN A 1 119  ? 137.330 106.852 73.072  1.00 41.76  ? 137  GLN A C     1 
ATOM   531   O  O     . GLN A 1 119  ? 136.127 106.666 73.284  1.00 41.76  ? 137  GLN A O     1 
ATOM   532   C  CB    . GLN A 1 119  ? 138.097 106.572 70.701  1.00 41.76  ? 137  GLN A CB    1 
ATOM   533   C  CG    . GLN A 1 119  ? 138.337 107.214 69.348  1.00 41.76  ? 137  GLN A CG    1 
ATOM   534   C  CD    . GLN A 1 119  ? 138.674 106.203 68.274  1.00 41.76  ? 137  GLN A CD    1 
ATOM   535   O  OE1   . GLN A 1 119  ? 138.303 105.033 68.366  1.00 41.76  ? 137  GLN A OE1   1 
ATOM   536   N  NE2   . GLN A 1 119  ? 139.387 106.650 67.247  1.00 41.76  ? 137  GLN A NE2   1 
ATOM   537   N  N     . HIS A 1 120  ? 138.276 106.450 73.922  1.00 39.58  ? 138  HIS A N     1 
ATOM   538   C  CA    . HIS A 1 120  ? 137.925 105.823 75.191  1.00 39.58  ? 138  HIS A CA    1 
ATOM   539   C  C     . HIS A 1 120  ? 137.066 106.752 76.038  1.00 39.58  ? 138  HIS A C     1 
ATOM   540   O  O     . HIS A 1 120  ? 136.000 106.361 76.534  1.00 39.58  ? 138  HIS A O     1 
ATOM   541   C  CB    . HIS A 1 120  ? 139.204 105.438 75.936  1.00 39.58  ? 138  HIS A CB    1 
ATOM   542   C  CG    . HIS A 1 120  ? 138.978 104.950 77.332  1.00 39.58  ? 138  HIS A CG    1 
ATOM   543   N  ND1   . HIS A 1 120  ? 138.188 103.859 77.623  1.00 39.58  ? 138  HIS A ND1   1 
ATOM   544   C  CD2   . HIS A 1 120  ? 139.458 105.393 78.518  1.00 39.58  ? 138  HIS A CD2   1 
ATOM   545   C  CE1   . HIS A 1 120  ? 138.185 103.656 78.929  1.00 39.58  ? 138  HIS A CE1   1 
ATOM   546   N  NE2   . HIS A 1 120  ? 138.947 104.574 79.495  1.00 39.58  ? 138  HIS A NE2   1 
ATOM   547   N  N     . PHE A 1 121  ? 137.524 107.981 76.217  1.00 33.30  ? 139  PHE A N     1 
ATOM   548   C  CA    . PHE A 1 121  ? 136.745 108.918 77.002  1.00 33.30  ? 139  PHE A CA    1 
ATOM   549   C  C     . PHE A 1 121  ? 135.403 109.136 76.327  1.00 33.30  ? 139  PHE A C     1 
ATOM   550   O  O     . PHE A 1 121  ? 134.355 108.999 76.955  1.00 33.30  ? 139  PHE A O     1 
ATOM   551   C  CB    . PHE A 1 121  ? 137.497 110.225 77.213  1.00 33.30  ? 139  PHE A CB    1 
ATOM   552   C  CG    . PHE A 1 121  ? 138.236 110.271 78.514  1.00 33.30  ? 139  PHE A CG    1 
ATOM   553   C  CD1   . PHE A 1 121  ? 137.578 109.980 79.697  1.00 33.30  ? 139  PHE A CD1   1 
ATOM   554   C  CD2   . PHE A 1 121  ? 139.580 110.581 78.561  1.00 33.30  ? 139  PHE A CD2   1 
ATOM   555   C  CE1   . PHE A 1 121  ? 138.243 110.008 80.903  1.00 33.30  ? 139  PHE A CE1   1 
ATOM   556   C  CE2   . PHE A 1 121  ? 140.253 110.611 79.766  1.00 33.30  ? 139  PHE A CE2   1 
ATOM   557   C  CZ    . PHE A 1 121  ? 139.584 110.325 80.938  1.00 33.30  ? 139  PHE A CZ    1 
ATOM   558   N  N     . ARG A 1 122  ? 135.427 109.439 75.037  1.00 30.31  ? 140  ARG A N     1 
ATOM   559   C  CA    . ARG A 1 122  ? 134.171 109.727 74.356  1.00 30.31  ? 140  ARG A CA    1 
ATOM   560   C  C     . ARG A 1 122  ? 133.156 108.621 74.591  1.00 30.31  ? 140  ARG A C     1 
ATOM   561   O  O     . ARG A 1 122  ? 131.986 108.898 74.867  1.00 30.31  ? 140  ARG A O     1 
ATOM   562   C  CB    . ARG A 1 122  ? 134.408 109.928 72.861  1.00 30.31  ? 140  ARG A CB    1 
ATOM   563   C  CG    . ARG A 1 122  ? 134.995 111.279 72.516  1.00 30.31  ? 140  ARG A CG    1 
ATOM   564   C  CD    . ARG A 1 122  ? 135.057 111.486 71.018  1.00 30.31  ? 140  ARG A CD    1 
ATOM   565   N  NE    . ARG A 1 122  ? 135.622 112.785 70.679  1.00 30.31  ? 140  ARG A NE    1 
ATOM   566   C  CZ    . ARG A 1 122  ? 134.907 113.882 70.476  1.00 30.31  ? 140  ARG A CZ    1 
ATOM   567   N  NH1   . ARG A 1 122  ? 133.587 113.871 70.559  1.00 30.31  ? 140  ARG A NH1   1 
ATOM   568   N  NH2   . ARG A 1 122  ? 135.531 115.019 70.183  1.00 30.31  ? 140  ARG A NH2   1 
ATOM   569   N  N     . LEU A 1 123  ? 133.584 107.360 74.503  1.00 30.82  ? 141  LEU A N     1 
ATOM   570   C  CA    . LEU A 1 123  ? 132.662 106.259 74.763  1.00 30.82  ? 141  LEU A CA    1 
ATOM   571   C  C     . LEU A 1 123  ? 132.203 106.257 76.214  1.00 30.82  ? 141  LEU A C     1 
ATOM   572   O  O     . LEU A 1 123  ? 131.022 106.018 76.497  1.00 30.82  ? 141  LEU A O     1 
ATOM   573   C  CB    . LEU A 1 123  ? 133.309 104.923 74.402  1.00 30.82  ? 141  LEU A CB    1 
ATOM   574   C  CG    . LEU A 1 123  ? 133.621 104.688 72.923  1.00 30.82  ? 141  LEU A CG    1 
ATOM   575   C  CD1   . LEU A 1 123  ? 134.021 103.240 72.681  1.00 30.82  ? 141  LEU A CD1   1 
ATOM   576   C  CD2   . LEU A 1 123  ? 132.440 105.076 72.051  1.00 30.82  ? 141  LEU A CD2   1 
ATOM   577   N  N     . LEU A 1 124  ? 133.118 106.533 77.147  1.00 31.62  ? 142  LEU A N     1 
ATOM   578   C  CA    . LEU A 1 124  ? 132.741 106.607 78.556  1.00 31.62  ? 142  LEU A CA    1 
ATOM   579   C  C     . LEU A 1 124  ? 131.685 107.680 78.786  1.00 31.62  ? 142  LEU A C     1 
ATOM   580   O  O     . LEU A 1 124  ? 130.635 107.422 79.390  1.00 31.62  ? 142  LEU A O     1 
ATOM   581   C  CB    . LEU A 1 124  ? 133.976 106.888 79.412  1.00 31.62  ? 142  LEU A CB    1 
ATOM   582   C  CG    . LEU A 1 124  ? 134.707 105.710 80.052  1.00 31.62  ? 142  LEU A CG    1 
ATOM   583   C  CD1   . LEU A 1 124  ? 134.876 104.570 79.066  1.00 31.62  ? 142  LEU A CD1   1 
ATOM   584   C  CD2   . LEU A 1 124  ? 136.054 106.176 80.570  1.00 31.62  ? 142  LEU A CD2   1 
ATOM   585   N  N     . ALA A 1 125  ? 131.946 108.892 78.297  1.00 28.72  ? 143  ALA A N     1 
ATOM   586   C  CA    . ALA A 1 125  ? 131.029 110.002 78.517  1.00 28.72  ? 143  ALA A CA    1 
ATOM   587   C  C     . ALA A 1 125  ? 129.702 109.779 77.805  1.00 28.72  ? 143  ALA A C     1 
ATOM   588   O  O     . ALA A 1 125  ? 128.651 110.182 78.311  1.00 28.72  ? 143  ALA A O     1 
ATOM   589   C  CB    . ALA A 1 125  ? 131.676 111.306 78.064  1.00 28.72  ? 143  ALA A CB    1 
ATOM   590   N  N     . GLN A 1 126  ? 129.725 109.154 76.626  1.00 26.99  ? 144  GLN A N     1 
ATOM   591   C  CA    . GLN A 1 126  ? 128.479 108.851 75.932  1.00 26.99  ? 144  GLN A CA    1 
ATOM   592   C  C     . GLN A 1 126  ? 127.647 107.841 76.711  1.00 26.99  ? 144  GLN A C     1 
ATOM   593   O  O     . GLN A 1 126  ? 126.436 108.025 76.882  1.00 26.99  ? 144  GLN A O     1 
ATOM   594   C  CB    . GLN A 1 126  ? 128.770 108.339 74.522  1.00 26.99  ? 144  GLN A CB    1 
ATOM   595   C  CG    . GLN A 1 126  ? 129.168 109.426 73.543  1.00 26.99  ? 144  GLN A CG    1 
ATOM   596   C  CD    . GLN A 1 126  ? 129.394 108.892 72.145  1.00 26.99  ? 144  GLN A CD    1 
ATOM   597   O  OE1   . GLN A 1 126  ? 129.282 107.692 71.901  1.00 26.99  ? 144  GLN A OE1   1 
ATOM   598   N  NE2   . GLN A 1 126  ? 129.713 109.785 71.216  1.00 26.99  ? 144  GLN A NE2   1 
ATOM   599   N  N     . LYS A 1 127  ? 128.276 106.769 77.200  1.00 27.98  ? 145  LYS A N     1 
ATOM   600   C  CA    . LYS A 1 127  ? 127.529 105.797 77.990  1.00 27.98  ? 145  LYS A CA    1 
ATOM   601   C  C     . LYS A 1 127  ? 127.025 106.407 79.290  1.00 27.98  ? 145  LYS A C     1 
ATOM   602   O  O     . LYS A 1 127  ? 125.993 105.979 79.819  1.00 27.98  ? 145  LYS A O     1 
ATOM   603   C  CB    . LYS A 1 127  ? 128.391 104.570 78.280  1.00 27.98  ? 145  LYS A CB    1 
ATOM   604   C  CG    . LYS A 1 127  ? 127.640 103.449 78.978  1.00 27.98  ? 145  LYS A CG    1 
ATOM   605   C  CD    . LYS A 1 127  ? 128.542 102.266 79.262  1.00 27.98  ? 145  LYS A CD    1 
ATOM   606   C  CE    . LYS A 1 127  ? 127.776 101.153 79.954  1.00 27.98  ? 145  LYS A CE    1 
ATOM   607   N  NZ    . LYS A 1 127  ? 128.646 99.984  80.255  1.00 27.98  ? 145  LYS A NZ    1 
ATOM   608   N  N     . GLN A 1 128  ? 127.731 107.408 79.817  1.00 28.38  ? 146  GLN A N     1 
ATOM   609   C  CA    . GLN A 1 128  ? 127.272 108.069 81.034  1.00 28.38  ? 146  GLN A CA    1 
ATOM   610   C  C     . GLN A 1 128  ? 126.074 108.970 80.757  1.00 28.38  ? 146  GLN A C     1 
ATOM   611   O  O     . GLN A 1 128  ? 124.994 108.782 81.330  1.00 28.38  ? 146  GLN A O     1 
ATOM   612   C  CB    . GLN A 1 128  ? 128.419 108.863 81.661  1.00 28.38  ? 146  GLN A CB    1 
ATOM   613   C  CG    . GLN A 1 128  ? 129.471 107.993 82.320  1.00 28.38  ? 146  GLN A CG    1 
ATOM   614   C  CD    . GLN A 1 128  ? 130.581 108.799 82.955  1.00 28.38  ? 146  GLN A CD    1 
ATOM   615   O  OE1   . GLN A 1 128  ? 130.586 110.026 82.890  1.00 28.38  ? 146  GLN A OE1   1 
ATOM   616   N  NE2   . GLN A 1 128  ? 131.532 108.110 83.574  1.00 28.38  ? 146  GLN A NE2   1 
ATOM   617   N  N     . SER A 1 129  ? 126.244 109.954 79.870  1.00 29.42  ? 147  SER A N     1 
ATOM   618   C  CA    . SER A 1 129  ? 125.230 110.971 79.613  1.00 29.42  ? 147  SER A CA    1 
ATOM   619   C  C     . SER A 1 129  ? 124.310 110.618 78.453  1.00 29.42  ? 147  SER A C     1 
ATOM   620   O  O     . SER A 1 129  ? 123.724 111.518 77.840  1.00 29.42  ? 147  SER A O     1 
ATOM   621   C  CB    . SER A 1 129  ? 125.898 112.322 79.358  1.00 29.42  ? 147  SER A CB    1 
ATOM   622   O  OG    . SER A 1 129  ? 126.546 112.337 78.100  1.00 29.42  ? 147  SER A OG    1 
ATOM   623   N  N     . LEU A 1 130  ? 124.168 109.340 78.126  1.00 34.07  ? 148  LEU A N     1 
ATOM   624   C  CA    . LEU A 1 130  ? 123.208 108.954 77.101  1.00 34.07  ? 148  LEU A CA    1 
ATOM   625   C  C     . LEU A 1 130  ? 121.772 109.065 77.616  1.00 34.07  ? 148  LEU A C     1 
ATOM   626   O  O     . LEU A 1 130  ? 120.966 109.772 77.000  1.00 34.07  ? 148  LEU A O     1 
ATOM   627   C  CB    . LEU A 1 130  ? 123.498 107.540 76.589  1.00 34.07  ? 148  LEU A CB    1 
ATOM   628   C  CG    . LEU A 1 130  ? 122.540 106.992 75.532  1.00 34.07  ? 148  LEU A CG    1 
ATOM   629   C  CD1   . LEU A 1 130  ? 122.732 107.711 74.206  1.00 34.07  ? 148  LEU A CD1   1 
ATOM   630   C  CD2   . LEU A 1 130  ? 122.718 105.491 75.369  1.00 34.07  ? 148  LEU A CD2   1 
ATOM   631   N  N     . PRO A 1 131  ? 121.397 108.402 78.721  1.00 37.19  ? 149  PRO A N     1 
ATOM   632   C  CA    . PRO A 1 131  ? 119.982 108.423 79.132  1.00 37.19  ? 149  PRO A CA    1 
ATOM   633   C  C     . PRO A 1 131  ? 119.487 109.783 79.592  1.00 37.19  ? 149  PRO A C     1 
ATOM   634   O  O     . PRO A 1 131  ? 118.268 109.973 79.684  1.00 37.19  ? 149  PRO A O     1 
ATOM   635   C  CB    . PRO A 1 131  ? 119.929 107.407 80.283  1.00 37.19  ? 149  PRO A CB    1 
ATOM   636   C  CG    . PRO A 1 131  ? 121.207 106.645 80.205  1.00 37.19  ? 149  PRO A CG    1 
ATOM   637   C  CD    . PRO A 1 131  ? 122.201 107.616 79.672  1.00 37.19  ? 149  PRO A CD    1 
ATOM   638   N  N     . TYR A 1 132  ? 120.378 110.726 79.888  1.00 34.14  ? 150  TYR A N     1 
ATOM   639   C  CA    . TYR A 1 132  ? 119.976 112.052 80.339  1.00 34.14  ? 150  TYR A CA    1 
ATOM   640   C  C     . TYR A 1 132  ? 119.892 113.062 79.210  1.00 34.14  ? 150  TYR A C     1 
ATOM   641   O  O     . TYR A 1 132  ? 119.025 113.942 79.240  1.00 34.14  ? 150  TYR A O     1 
ATOM   642   C  CB    . TYR A 1 132  ? 120.950 112.556 81.407  1.00 34.14  ? 150  TYR A CB    1 
ATOM   643   C  CG    . TYR A 1 132  ? 121.043 111.619 82.584  1.00 34.14  ? 150  TYR A CG    1 
ATOM   644   C  CD1   . TYR A 1 132  ? 119.901 111.217 83.260  1.00 34.14  ? 150  TYR A CD1   1 
ATOM   645   C  CD2   . TYR A 1 132  ? 122.262 111.107 82.999  1.00 34.14  ? 150  TYR A CD2   1 
ATOM   646   C  CE1   . TYR A 1 132  ? 119.972 110.355 84.326  1.00 34.14  ? 150  TYR A CE1   1 
ATOM   647   C  CE2   . TYR A 1 132  ? 122.340 110.237 84.066  1.00 34.14  ? 150  TYR A CE2   1 
ATOM   648   C  CZ    . TYR A 1 132  ? 121.189 109.867 84.725  1.00 34.14  ? 150  TYR A CZ    1 
ATOM   649   O  OH    . TYR A 1 132  ? 121.250 109.004 85.791  1.00 34.14  ? 150  TYR A OH    1 
ATOM   650   N  N     . LEU A 1 133  ? 120.764 112.950 78.208  1.00 31.24  ? 151  LEU A N     1 
ATOM   651   C  CA    . LEU A 1 133  ? 120.600 113.759 77.008  1.00 31.24  ? 151  LEU A CA    1 
ATOM   652   C  C     . LEU A 1 133  ? 119.319 113.388 76.274  1.00 31.24  ? 151  LEU A C     1 
ATOM   653   O  O     . LEU A 1 133  ? 118.688 114.251 75.652  1.00 31.24  ? 151  LEU A O     1 
ATOM   654   C  CB    . LEU A 1 133  ? 121.816 113.598 76.101  1.00 31.24  ? 151  LEU A CB    1 
ATOM   655   C  CG    . LEU A 1 133  ? 122.082 114.759 75.148  1.00 31.24  ? 151  LEU A CG    1 
ATOM   656   C  CD1   . LEU A 1 133  ? 121.960 116.067 75.897  1.00 31.24  ? 151  LEU A CD1   1 
ATOM   657   C  CD2   . LEU A 1 133  ? 123.459 114.628 74.529  1.00 31.24  ? 151  LEU A CD2   1 
ATOM   658   N  N     . GLU A 1 134  ? 118.910 112.120 76.352  1.00 37.58  ? 152  GLU A N     1 
ATOM   659   C  CA    . GLU A 1 134  ? 117.620 111.722 75.801  1.00 37.58  ? 152  GLU A CA    1 
ATOM   660   C  C     . GLU A 1 134  ? 116.476 112.453 76.492  1.00 37.58  ? 152  GLU A C     1 
ATOM   661   O  O     . GLU A 1 134  ? 115.553 112.940 75.831  1.00 37.58  ? 152  GLU A O     1 
ATOM   662   C  CB    . GLU A 1 134  ? 117.435 110.210 75.929  1.00 37.58  ? 152  GLU A CB    1 
ATOM   663   C  CG    . GLU A 1 134  ? 118.414 109.381 75.120  1.00 37.58  ? 152  GLU A CG    1 
ATOM   664   C  CD    . GLU A 1 134  ? 118.292 107.897 75.407  1.00 37.58  ? 152  GLU A CD    1 
ATOM   665   O  OE1   . GLU A 1 134  ? 117.443 107.517 76.241  1.00 37.58  ? 152  GLU A OE1   1 
ATOM   666   O  OE2   . GLU A 1 134  ? 119.048 107.110 74.800  1.00 37.58  ? 152  GLU A OE2   1 
ATOM   667   N  N     . ALA A 1 135  ? 116.517 112.539 77.824  1.00 33.50  ? 153  ALA A N     1 
ATOM   668   C  CA    . ALA A 1 135  ? 115.466 113.243 78.552  1.00 33.50  ? 153  ALA A CA    1 
ATOM   669   C  C     . ALA A 1 135  ? 115.499 114.737 78.258  1.00 33.50  ? 153  ALA A C     1 
ATOM   670   O  O     . ALA A 1 135  ? 114.447 115.379 78.142  1.00 33.50  ? 153  ALA A O     1 
ATOM   671   C  CB    . ALA A 1 135  ? 115.601 112.982 80.051  1.00 33.50  ? 153  ALA A CB    1 
ATOM   672   N  N     . ALA A 1 136  ? 116.699 115.307 78.138  1.00 35.06  ? 154  ALA A N     1 
ATOM   673   C  CA    . ALA A 1 136  ? 116.814 116.713 77.766  1.00 35.06  ? 154  ALA A CA    1 
ATOM   674   C  C     . ALA A 1 136  ? 116.195 116.971 76.398  1.00 35.06  ? 154  ALA A C     1 
ATOM   675   O  O     . ALA A 1 136  ? 115.500 117.973 76.203  1.00 35.06  ? 154  ALA A O     1 
ATOM   676   C  CB    . ALA A 1 136  ? 118.278 117.147 77.784  1.00 35.06  ? 154  ALA A CB    1 
ATOM   677   N  N     . ASN A 1 137  ? 116.435 116.076 75.435  1.00 36.58  ? 155  ASN A N     1 
ATOM   678   C  CA    . ASN A 1 137  ? 115.818 116.224 74.120  1.00 36.58  ? 155  ASN A CA    1 
ATOM   679   C  C     . ASN A 1 137  ? 114.307 116.040 74.188  1.00 36.58  ? 155  ASN A C     1 
ATOM   680   O  O     . ASN A 1 137  ? 113.561 116.746 73.499  1.00 36.58  ? 155  ASN A O     1 
ATOM   681   C  CB    . ASN A 1 137  ? 116.439 115.239 73.132  1.00 36.58  ? 155  ASN A CB    1 
ATOM   682   C  CG    . ASN A 1 137  ? 117.831 115.651 72.700  1.00 36.58  ? 155  ASN A CG    1 
ATOM   683   O  OD1   . ASN A 1 137  ? 118.169 116.834 72.710  1.00 36.58  ? 155  ASN A OD1   1 
ATOM   684   N  ND2   . ASN A 1 137  ? 118.646 114.676 72.316  1.00 36.58  ? 155  ASN A ND2   1 
ATOM   685   N  N     . LEU A 1 138  ? 113.837 115.091 75.002  1.00 32.21  ? 156  LEU A N     1 
ATOM   686   C  CA    . LEU A 1 138  ? 112.400 114.904 75.178  1.00 32.21  ? 156  LEU A CA    1 
ATOM   687   C  C     . LEU A 1 138  ? 111.745 116.172 75.701  1.00 32.21  ? 156  LEU A C     1 
ATOM   688   O  O     . LEU A 1 138  ? 110.650 116.545 75.265  1.00 32.21  ? 156  LEU A O     1 
ATOM   689   C  CB    . LEU A 1 138  ? 112.129 113.745 76.137  1.00 32.21  ? 156  LEU A CB    1 
ATOM   690   C  CG    . LEU A 1 138  ? 111.596 112.433 75.568  1.00 32.21  ? 156  LEU A CG    1 
ATOM   691   C  CD1   . LEU A 1 138  ? 112.684 111.701 74.807  1.00 32.21  ? 156  LEU A CD1   1 
ATOM   692   C  CD2   . LEU A 1 138  ? 111.035 111.566 76.683  1.00 32.21  ? 156  LEU A CD2   1 
ATOM   693   N  N     . LEU A 1 139  ? 112.401 116.841 76.645  1.00 36.97  ? 157  LEU A N     1 
ATOM   694   C  CA    . LEU A 1 139  ? 111.871 118.081 77.197  1.00 36.97  ? 157  LEU A CA    1 
ATOM   695   C  C     . LEU A 1 139  ? 112.020 119.247 76.227  1.00 36.97  ? 157  LEU A C     1 
ATOM   696   O  O     . LEU A 1 139  ? 111.218 120.186 76.267  1.00 36.97  ? 157  LEU A O     1 
ATOM   697   C  CB    . LEU A 1 139  ? 112.574 118.394 78.517  1.00 36.97  ? 157  LEU A CB    1 
ATOM   698   C  CG    . LEU A 1 139  ? 111.984 119.488 79.400  1.00 36.97  ? 157  LEU A CG    1 
ATOM   699   C  CD1   . LEU A 1 139  ? 110.613 119.084 79.912  1.00 36.97  ? 157  LEU A CD1   1 
ATOM   700   C  CD2   . LEU A 1 139  ? 112.928 119.765 80.545  1.00 36.97  ? 157  LEU A CD2   1 
ATOM   701   N  N     . LEU A 1 140  ? 113.036 119.206 75.362  1.00 38.80  ? 158  LEU A N     1 
ATOM   702   C  CA    . LEU A 1 140  ? 113.278 120.304 74.432  1.00 38.80  ? 158  LEU A CA    1 
ATOM   703   C  C     . LEU A 1 140  ? 112.136 120.458 73.434  1.00 38.80  ? 158  LEU A C     1 
ATOM   704   O  O     . LEU A 1 140  ? 111.726 121.581 73.118  1.00 38.80  ? 158  LEU A O     1 
ATOM   705   C  CB    . LEU A 1 140  ? 114.605 120.078 73.705  1.00 38.80  ? 158  LEU A CB    1 
ATOM   706   C  CG    . LEU A 1 140  ? 114.867 120.798 72.382  1.00 38.80  ? 158  LEU A CG    1 
ATOM   707   C  CD1   . LEU A 1 140  ? 114.870 122.299 72.567  1.00 38.80  ? 158  LEU A CD1   1 
ATOM   708   C  CD2   . LEU A 1 140  ? 116.185 120.332 71.782  1.00 38.80  ? 158  LEU A CD2   1 
ATOM   709   N  N     . GLN A 1 141  ? 111.611 119.348 72.927  1.00 44.12  ? 159  GLN A N     1 
ATOM   710   C  CA    . GLN A 1 141  ? 110.529 119.365 71.945  1.00 44.12  ? 159  GLN A CA    1 
ATOM   711   C  C     . GLN A 1 141  ? 109.313 118.685 72.564  1.00 44.12  ? 159  GLN A C     1 
ATOM   712   O  O     . GLN A 1 141  ? 109.249 117.454 72.641  1.00 44.12  ? 159  GLN A O     1 
ATOM   713   C  CB    . GLN A 1 141  ? 110.958 118.689 70.644  1.00 44.12  ? 159  GLN A CB    1 
ATOM   714   C  CG    . GLN A 1 141  ? 111.746 117.401 70.827  1.00 44.12  ? 159  GLN A CG    1 
ATOM   715   C  CD    . GLN A 1 141  ? 112.074 116.728 69.510  1.00 44.12  ? 159  GLN A CD    1 
ATOM   716   O  OE1   . GLN A 1 141  ? 111.826 117.282 68.439  1.00 44.12  ? 159  GLN A OE1   1 
ATOM   717   N  NE2   . GLN A 1 141  ? 112.632 115.525 69.582  1.00 44.12  ? 159  GLN A NE2   1 
ATOM   718   N  N     . ALA A 1 142  ? 108.347 119.487 73.006  1.00 51.32  ? 160  ALA A N     1 
ATOM   719   C  CA    . ALA A 1 142  ? 107.147 118.957 73.632  1.00 51.32  ? 160  ALA A CA    1 
ATOM   720   C  C     . ALA A 1 142  ? 106.011 119.953 73.469  1.00 51.32  ? 160  ALA A C     1 
ATOM   721   O  O     . ALA A 1 142  ? 106.223 121.124 73.145  1.00 51.32  ? 160  ALA A O     1 
ATOM   722   C  CB    . ALA A 1 142  ? 107.374 118.647 75.116  1.00 51.32  ? 160  ALA A CB    1 
ATOM   723   N  N     . GLN A 1 143  ? 104.795 119.466 73.696  1.00 58.22  ? 161  GLN A N     1 
ATOM   724   C  CA    . GLN A 1 143  ? 103.592 120.283 73.654  1.00 58.22  ? 161  GLN A CA    1 
ATOM   725   C  C     . GLN A 1 143  ? 102.995 120.355 75.052  1.00 58.22  ? 161  GLN A C     1 
ATOM   726   O  O     . GLN A 1 143  ? 102.751 119.321 75.683  1.00 58.22  ? 161  GLN A O     1 
ATOM   727   C  CB    . GLN A 1 143  ? 102.580 119.712 72.658  1.00 58.22  ? 161  GLN A CB    1 
ATOM   728   C  CG    . GLN A 1 143  ? 102.420 118.203 72.734  1.00 58.22  ? 161  GLN A CG    1 
ATOM   729   C  CD    . GLN A 1 143  ? 101.548 117.653 71.624  1.00 58.22  ? 161  GLN A CD    1 
ATOM   730   O  OE1   . GLN A 1 143  ? 100.934 118.407 70.870  1.00 58.22  ? 161  GLN A OE1   1 
ATOM   731   N  NE2   . GLN A 1 143  ? 101.493 116.330 71.516  1.00 58.22  ? 161  GLN A NE2   1 
ATOM   732   N  N     . LEU A 1 144  ? 102.766 121.575 75.532  1.00 49.70  ? 162  LEU A N     1 
ATOM   733   C  CA    . LEU A 1 144  ? 102.353 121.804 76.905  1.00 49.70  ? 162  LEU A CA    1 
ATOM   734   C  C     . LEU A 1 144  ? 100.933 122.338 76.962  1.00 49.70  ? 162  LEU A C     1 
ATOM   735   O  O     . LEU A 1 144  ? 100.628 123.341 76.303  1.00 49.70  ? 162  LEU A O     1 
ATOM   736   C  CB    . LEU A 1 144  ? 103.304 122.793 77.586  1.00 49.70  ? 162  LEU A CB    1 
ATOM   737   C  CG    . LEU A 1 144  ? 104.715 122.296 77.891  1.00 49.70  ? 162  LEU A CG    1 
ATOM   738   C  CD1   . LEU A 1 144  ? 105.673 123.466 78.006  1.00 49.70  ? 162  LEU A CD1   1 
ATOM   739   C  CD2   . LEU A 1 144  ? 104.716 121.477 79.171  1.00 49.70  ? 162  LEU A CD2   1 
ATOM   740   N  N     . PRO A 1 145  ? 100.047 121.707 77.726  1.00 54.50  ? 163  PRO A N     1 
ATOM   741   C  CA    . PRO A 1 145  ? 98.712  122.271 77.939  1.00 54.50  ? 163  PRO A CA    1 
ATOM   742   C  C     . PRO A 1 145  ? 98.798  123.570 78.718  1.00 54.50  ? 163  PRO A C     1 
ATOM   743   O  O     . PRO A 1 145  ? 99.788  123.812 79.426  1.00 54.50  ? 163  PRO A O     1 
ATOM   744   C  CB    . PRO A 1 145  ? 97.990  121.180 78.747  1.00 54.50  ? 163  PRO A CB    1 
ATOM   745   C  CG    . PRO A 1 145  ? 98.772  119.932 78.498  1.00 54.50  ? 163  PRO A CG    1 
ATOM   746   C  CD    . PRO A 1 145  ? 100.191 120.379 78.343  1.00 54.50  ? 163  PRO A CD    1 
ATOM   747   N  N     . PRO A 1 146  ? 97.795  124.438 78.605  1.00 53.08  ? 164  PRO A N     1 
ATOM   748   C  CA    . PRO A 1 146  ? 97.835  125.707 79.339  1.00 53.08  ? 164  PRO A CA    1 
ATOM   749   C  C     . PRO A 1 146  ? 97.777  125.493 80.843  1.00 53.08  ? 164  PRO A C     1 
ATOM   750   O  O     . PRO A 1 146  ? 97.252  124.489 81.333  1.00 53.08  ? 164  PRO A O     1 
ATOM   751   C  CB    . PRO A 1 146  ? 96.592  126.447 78.835  1.00 53.08  ? 164  PRO A CB    1 
ATOM   752   C  CG    . PRO A 1 146  ? 95.672  125.364 78.383  1.00 53.08  ? 164  PRO A CG    1 
ATOM   753   C  CD    . PRO A 1 146  ? 96.562  124.298 77.813  1.00 53.08  ? 164  PRO A CD    1 
ATOM   754   N  N     . LYS A 1 147  ? 98.338  126.452 81.573  1.00 50.87  ? 165  LYS A N     1 
ATOM   755   C  CA    . LYS A 1 147  ? 98.343  126.379 83.027  1.00 50.87  ? 165  LYS A CA    1 
ATOM   756   C  C     . LYS A 1 147  ? 96.908  126.333 83.542  1.00 50.87  ? 165  LYS A C     1 
ATOM   757   O  O     . LYS A 1 147  ? 96.102  127.207 83.193  1.00 50.87  ? 165  LYS A O     1 
ATOM   758   C  CB    . LYS A 1 147  ? 99.072  127.580 83.622  1.00 50.87  ? 165  LYS A CB    1 
ATOM   759   C  CG    . LYS A 1 147  ? 100.350 127.949 82.899  1.00 50.87  ? 165  LYS A CG    1 
ATOM   760   C  CD    . LYS A 1 147  ? 100.962 129.206 83.483  1.00 50.87  ? 165  LYS A CD    1 
ATOM   761   C  CE    . LYS A 1 147  ? 102.137 129.675 82.652  1.00 50.87  ? 165  LYS A CE    1 
ATOM   762   N  NZ    . LYS A 1 147  ? 101.727 129.977 81.256  1.00 50.87  ? 165  LYS A NZ    1 
ATOM   763   N  N     . PRO A 1 148  ? 96.547  125.337 84.348  1.00 54.84  ? 166  PRO A N     1 
ATOM   764   C  CA    . PRO A 1 148  ? 95.168  125.242 84.813  1.00 54.84  ? 166  PRO A CA    1 
ATOM   765   C  C     . PRO A 1 148  ? 94.799  126.451 85.650  1.00 54.84  ? 166  PRO A C     1 
ATOM   766   O  O     . PRO A 1 148  ? 95.635  126.988 86.401  1.00 54.84  ? 166  PRO A O     1 
ATOM   767   C  CB    . PRO A 1 148  ? 95.165  123.955 85.648  1.00 54.84  ? 166  PRO A CB    1 
ATOM   768   C  CG    . PRO A 1 148  ? 96.322  123.170 85.134  1.00 54.84  ? 166  PRO A CG    1 
ATOM   769   C  CD    . PRO A 1 148  ? 97.357  124.187 84.779  1.00 54.84  ? 166  PRO A CD    1 
ATOM   770   N  N     . PRO A 1 149  ? 93.556  126.922 85.543  1.00 53.88  ? 167  PRO A N     1 
ATOM   771   C  CA    . PRO A 1 149  ? 93.143  128.084 86.347  1.00 53.88  ? 167  PRO A CA    1 
ATOM   772   C  C     . PRO A 1 149  ? 93.189  127.835 87.844  1.00 53.88  ? 167  PRO A C     1 
ATOM   773   O  O     . PRO A 1 149  ? 93.465  128.766 88.610  1.00 53.88  ? 167  PRO A O     1 
ATOM   774   C  CB    . PRO A 1 149  ? 91.712  128.350 85.862  1.00 53.88  ? 167  PRO A CB    1 
ATOM   775   C  CG    . PRO A 1 149  ? 91.241  127.030 85.341  1.00 53.88  ? 167  PRO A CG    1 
ATOM   776   C  CD    . PRO A 1 149  ? 92.450  126.385 84.732  1.00 53.88  ? 167  PRO A CD    1 
ATOM   777   N  N     . ALA A 1 150  ? 92.930  126.607 88.285  1.00 54.23  ? 168  ALA A N     1 
ATOM   778   C  CA    . ALA A 1 150  ? 92.874  126.277 89.699  1.00 54.23  ? 168  ALA A CA    1 
ATOM   779   C  C     . ALA A 1 150  ? 93.906  125.210 90.033  1.00 54.23  ? 168  ALA A C     1 
ATOM   780   O  O     . ALA A 1 150  ? 94.383  124.476 89.162  1.00 54.23  ? 168  ALA A O     1 
ATOM   781   C  CB    . ALA A 1 150  ? 91.475  125.793 90.101  1.00 54.23  ? 168  ALA A CB    1 
ATOM   782   N  N     . TRP A 1 151  ? 94.247  125.134 91.316  1.00 52.63  ? 169  TRP A N     1 
ATOM   783   C  CA    . TRP A 1 151  ? 95.199  124.159 91.824  1.00 52.63  ? 169  TRP A CA    1 
ATOM   784   C  C     . TRP A 1 151  ? 94.576  123.420 92.998  1.00 52.63  ? 169  TRP A C     1 
ATOM   785   O  O     . TRP A 1 151  ? 93.684  123.940 93.674  1.00 52.63  ? 169  TRP A O     1 
ATOM   786   C  CB    . TRP A 1 151  ? 96.507  124.827 92.254  1.00 52.63  ? 169  TRP A CB    1 
ATOM   787   C  CG    . TRP A 1 151  ? 97.005  125.857 91.287  1.00 52.63  ? 169  TRP A CG    1 
ATOM   788   C  CD1   . TRP A 1 151  ? 96.691  127.183 91.269  1.00 52.63  ? 169  TRP A CD1   1 
ATOM   789   C  CD2   . TRP A 1 151  ? 97.911  125.647 90.199  1.00 52.63  ? 169  TRP A CD2   1 
ATOM   790   N  NE1   . TRP A 1 151  ? 97.342  127.812 90.239  1.00 52.63  ? 169  TRP A NE1   1 
ATOM   791   C  CE2   . TRP A 1 151  ? 98.099  126.891 89.566  1.00 52.63  ? 169  TRP A CE2   1 
ATOM   792   C  CE3   . TRP A 1 151  ? 98.583  124.528 89.699  1.00 52.63  ? 169  TRP A CE3   1 
ATOM   793   C  CZ2   . TRP A 1 151  ? 98.928  127.047 88.457  1.00 52.63  ? 169  TRP A CZ2   1 
ATOM   794   C  CZ3   . TRP A 1 151  ? 99.405  124.684 88.599  1.00 52.63  ? 169  TRP A CZ3   1 
ATOM   795   C  CH2   . TRP A 1 151  ? 99.571  125.933 87.990  1.00 52.63  ? 169  TRP A CH2   1 
ATOM   796   N  N     . ALA A 1 152  ? 95.049  122.200 93.234  1.00 55.81  ? 170  ALA A N     1 
ATOM   797   C  CA    . ALA A 1 152  ? 94.473  121.342 94.260  1.00 55.81  ? 170  ALA A CA    1 
ATOM   798   C  C     . ALA A 1 152  ? 95.128  121.592 95.611  1.00 55.81  ? 170  ALA A C     1 
ATOM   799   O  O     . ALA A 1 152  ? 96.351  121.719 95.712  1.00 55.81  ? 170  ALA A O     1 
ATOM   800   C  CB    . ALA A 1 152  ? 94.621  119.870 93.875  1.00 55.81  ? 170  ALA A CB    1 
ATOM   801   N  N     . TRP A 1 153  ? 94.300  121.657 96.649  1.00 57.94  ? 171  TRP A N     1 
ATOM   802   C  CA    . TRP A 1 153  ? 94.772  121.807 98.026  1.00 57.94  ? 171  TRP A CA    1 
ATOM   803   C  C     . TRP A 1 153  ? 94.913  120.435 98.684  1.00 57.94  ? 171  TRP A C     1 
ATOM   804   O  O     . TRP A 1 153  ? 94.281  120.118 99.691  1.00 57.94  ? 171  TRP A O     1 
ATOM   805   C  CB    . TRP A 1 153  ? 93.823  122.711 98.808  1.00 57.94  ? 171  TRP A CB    1 
ATOM   806   C  CG    . TRP A 1 153  ? 94.342  123.171 100.140 1.00 57.94  ? 171  TRP A CG    1 
ATOM   807   C  CD1   . TRP A 1 153  ? 94.179  122.549 101.345 1.00 57.94  ? 171  TRP A CD1   1 
ATOM   808   C  CD2   . TRP A 1 153  ? 95.088  124.364 100.405 1.00 57.94  ? 171  TRP A CD2   1 
ATOM   809   N  NE1   . TRP A 1 153  ? 94.785  123.276 102.339 1.00 57.94  ? 171  TRP A NE1   1 
ATOM   810   C  CE2   . TRP A 1 153  ? 95.349  124.396 101.788 1.00 57.94  ? 171  TRP A CE2   1 
ATOM   811   C  CE3   . TRP A 1 153  ? 95.563  125.407 99.605  1.00 57.94  ? 171  TRP A CE3   1 
ATOM   812   C  CZ2   . TRP A 1 153  ? 96.065  125.428 102.389 1.00 57.94  ? 171  TRP A CZ2   1 
ATOM   813   C  CZ3   . TRP A 1 153  ? 96.272  126.429 100.204 1.00 57.94  ? 171  TRP A CZ3   1 
ATOM   814   C  CH2   . TRP A 1 153  ? 96.517  126.433 101.581 1.00 57.94  ? 171  TRP A CH2   1 
ATOM   815   N  N     . ALA A 1 154  ? 95.751  119.605 98.074  1.00 67.78  ? 172  ALA A N     1 
ATOM   816   C  CA    . ALA A 1 154  ? 96.020  118.266 98.572  1.00 67.78  ? 172  ALA A CA    1 
ATOM   817   C  C     . ALA A 1 154  ? 97.198  118.310 99.544  1.00 67.78  ? 172  ALA A C     1 
ATOM   818   O  O     . ALA A 1 154  ? 97.640  119.378 99.974  1.00 67.78  ? 172  ALA A O     1 
ATOM   819   C  CB    . ALA A 1 154  ? 96.274  117.309 97.410  1.00 67.78  ? 172  ALA A CB    1 
ATOM   820   N  N     . GLU A 1 155  ? 97.714  117.137 99.912  1.00 66.74  ? 173  GLU A N     1 
ATOM   821   C  CA    . GLU A 1 155  ? 98.863  117.047 100.799 1.00 66.74  ? 173  GLU A CA    1 
ATOM   822   C  C     . GLU A 1 155  ? 100.139 116.608 100.093 1.00 66.74  ? 173  GLU A C     1 
ATOM   823   O  O     . GLU A 1 155  ? 101.229 116.834 100.629 1.00 66.74  ? 173  GLU A O     1 
ATOM   824   C  CB    . GLU A 1 155  ? 98.569  116.084 101.961 1.00 66.74  ? 173  GLU A CB    1 
ATOM   825   C  CG    . GLU A 1 155  ? 98.474  114.613 101.570 1.00 66.74  ? 173  GLU A CG    1 
ATOM   826   C  CD    . GLU A 1 155  ? 97.156  114.256 100.910 1.00 66.74  ? 173  GLU A CD    1 
ATOM   827   O  OE1   . GLU A 1 155  ? 96.266  115.129 100.836 1.00 66.74  ? 173  GLU A OE1   1 
ATOM   828   O  OE2   . GLU A 1 155  ? 97.010  113.098 100.465 1.00 66.74  ? 173  GLU A OE2   1 
ATOM   829   N  N     . GLY A 1 156  ? 100.037 115.998 98.915  1.00 53.58  ? 174  GLY A N     1 
ATOM   830   C  CA    . GLY A 1 156  ? 101.182 115.519 98.176  1.00 53.58  ? 174  GLY A CA    1 
ATOM   831   C  C     . GLY A 1 156  ? 101.212 116.090 96.770  1.00 53.58  ? 174  GLY A C     1 
ATOM   832   O  O     . GLY A 1 156  ? 100.780 117.215 96.518  1.00 53.58  ? 174  GLY A O     1 
ATOM   833   N  N     . TRP A 1 157  ? 101.742 115.289 95.849  1.00 39.29  ? 175  TRP A N     1 
ATOM   834   C  CA    . TRP A 1 157  ? 101.840 115.707 94.459  1.00 39.29  ? 175  TRP A CA    1 
ATOM   835   C  C     . TRP A 1 157  ? 100.467 115.745 93.802  1.00 39.29  ? 175  TRP A C     1 
ATOM   836   O  O     . TRP A 1 157  ? 99.554  115.000 94.167  1.00 39.29  ? 175  TRP A O     1 
ATOM   837   C  CB    . TRP A 1 157  ? 102.757 114.768 93.676  1.00 39.29  ? 175  TRP A CB    1 
ATOM   838   C  CG    . TRP A 1 157  ? 104.177 115.193 93.688  1.00 39.29  ? 175  TRP A CG    1 
ATOM   839   C  CD1   . TRP A 1 157  ? 105.212 114.584 94.331  1.00 39.29  ? 175  TRP A CD1   1 
ATOM   840   C  CD2   . TRP A 1 157  ? 104.725 116.337 93.035  1.00 39.29  ? 175  TRP A CD2   1 
ATOM   841   N  NE1   . TRP A 1 157  ? 106.375 115.279 94.112  1.00 39.29  ? 175  TRP A NE1   1 
ATOM   842   C  CE2   . TRP A 1 157  ? 106.100 116.361 93.319  1.00 39.29  ? 175  TRP A CE2   1 
ATOM   843   C  CE3   . TRP A 1 157  ? 104.184 117.344 92.234  1.00 39.29  ? 175  TRP A CE3   1 
ATOM   844   C  CZ2   . TRP A 1 157  ? 106.942 117.352 92.832  1.00 39.29  ? 175  TRP A CZ2   1 
ATOM   845   C  CZ3   . TRP A 1 157  ? 105.020 118.328 91.754  1.00 39.29  ? 175  TRP A CZ3   1 
ATOM   846   C  CH2   . TRP A 1 157  ? 106.383 118.325 92.051  1.00 39.29  ? 175  TRP A CH2   1 
ATOM   847   N  N     . THR A 1 158  ? 100.324 116.631 92.822  1.00 44.06  ? 176  THR A N     1 
ATOM   848   C  CA    . THR A 1 158  ? 99.107  116.710 92.032  1.00 44.06  ? 176  THR A CA    1 
ATOM   849   C  C     . THR A 1 158  ? 99.474  116.941 90.575  1.00 44.06  ? 176  THR A C     1 
ATOM   850   O  O     . THR A 1 158  ? 100.469 117.603 90.268  1.00 44.06  ? 176  THR A O     1 
ATOM   851   C  CB    . THR A 1 158  ? 98.179  117.825 92.526  1.00 44.06  ? 176  THR A CB    1 
ATOM   852   O  OG1   . THR A 1 158  ? 98.207  117.871 93.958  1.00 44.06  ? 176  THR A OG1   1 
ATOM   853   C  CG2   . THR A 1 158  ? 96.754  117.559 92.070  1.00 44.06  ? 176  THR A CG2   1 
ATOM   854   N  N     . ARG A 1 159  ? 98.660  116.386 89.679  1.00 48.35  ? 177  ARG A N     1 
ATOM   855   C  CA    . ARG A 1 159  ? 98.871  116.496 88.243  1.00 48.35  ? 177  ARG A CA    1 
ATOM   856   C  C     . ARG A 1 159  ? 97.568  116.901 87.574  1.00 48.35  ? 177  ARG A C     1 
ATOM   857   O  O     . ARG A 1 159  ? 96.521  116.297 87.831  1.00 48.35  ? 177  ARG A O     1 
ATOM   858   C  CB    . ARG A 1 159  ? 99.378  115.174 87.658  1.00 48.35  ? 177  ARG A CB    1 
ATOM   859   C  CG    . ARG A 1 159  ? 99.593  115.193 86.157  1.00 48.35  ? 177  ARG A CG    1 
ATOM   860   C  CD    . ARG A 1 159  ? 99.815  113.786 85.628  1.00 48.35  ? 177  ARG A CD    1 
ATOM   861   N  NE    . ARG A 1 159  ? 100.047 113.771 84.189  1.00 48.35  ? 177  ARG A NE    1 
ATOM   862   C  CZ    . ARG A 1 159  ? 100.198 112.669 83.469  1.00 48.35  ? 177  ARG A CZ    1 
ATOM   863   N  NH1   . ARG A 1 159  ? 100.135 111.469 84.021  1.00 48.35  ? 177  ARG A NH1   1 
ATOM   864   N  NH2   . ARG A 1 159  ? 100.419 112.773 82.161  1.00 48.35  ? 177  ARG A NH2   1 
ATOM   865   N  N     . TYR A 1 160  ? 97.640  117.925 86.719  1.00 53.49  ? 178  TYR A N     1 
ATOM   866   C  CA    . TYR A 1 160  ? 96.472  118.377 85.972  1.00 53.49  ? 178  TYR A CA    1 
ATOM   867   C  C     . TYR A 1 160  ? 96.766  118.321 84.484  1.00 53.49  ? 178  TYR A C     1 
ATOM   868   O  O     . TYR A 1 160  ? 97.764  118.882 84.034  1.00 53.49  ? 178  TYR A O     1 
ATOM   869   C  CB    . TYR A 1 160  ? 96.100  119.811 86.330  1.00 53.49  ? 178  TYR A CB    1 
ATOM   870   C  CG    . TYR A 1 160  ? 96.502  120.269 87.707  1.00 53.49  ? 178  TYR A CG    1 
ATOM   871   C  CD1   . TYR A 1 160  ? 95.707  119.995 88.807  1.00 53.49  ? 178  TYR A CD1   1 
ATOM   872   C  CD2   . TYR A 1 160  ? 97.661  121.006 87.901  1.00 53.49  ? 178  TYR A CD2   1 
ATOM   873   C  CE1   . TYR A 1 160  ? 96.064  120.427 90.067  1.00 53.49  ? 178  TYR A CE1   1 
ATOM   874   C  CE2   . TYR A 1 160  ? 98.026  121.441 89.158  1.00 53.49  ? 178  TYR A CE2   1 
ATOM   875   C  CZ    . TYR A 1 160  ? 97.222  121.148 90.235  1.00 53.49  ? 178  TYR A CZ    1 
ATOM   876   O  OH    . TYR A 1 160  ? 97.571  121.578 91.489  1.00 53.49  ? 178  TYR A OH    1 
ATOM   877   N  N     . GLY A 1 161  ? 95.914  117.662 83.712  1.00 66.23  ? 179  GLY A N     1 
ATOM   878   C  CA    . GLY A 1 161  ? 96.083  117.545 82.285  1.00 66.23  ? 179  GLY A CA    1 
ATOM   879   C  C     . GLY A 1 161  ? 95.011  118.298 81.527  1.00 66.23  ? 179  GLY A C     1 
ATOM   880   O  O     . GLY A 1 161  ? 94.554  119.367 81.946  1.00 66.23  ? 179  GLY A O     1 
ATOM   881   N  N     . PRO A 1 162  ? 94.599  117.756 80.380  1.00 73.28  ? 180  PRO A N     1 
ATOM   882   C  CA    . PRO A 1 162  ? 93.514  118.397 79.618  1.00 73.28  ? 180  PRO A CA    1 
ATOM   883   C  C     . PRO A 1 162  ? 92.210  118.497 80.390  1.00 73.28  ? 180  PRO A C     1 
ATOM   884   O  O     . PRO A 1 162  ? 91.477  119.479 80.223  1.00 73.28  ? 180  PRO A O     1 
ATOM   885   C  CB    . PRO A 1 162  ? 93.372  117.491 78.387  1.00 73.28  ? 180  PRO A CB    1 
ATOM   886   C  CG    . PRO A 1 162  ? 94.688  116.793 78.271  1.00 73.28  ? 180  PRO A CG    1 
ATOM   887   C  CD    . PRO A 1 162  ? 95.159  116.591 79.677  1.00 73.28  ? 180  PRO A CD    1 
ATOM   888   N  N     . GLU A 1 163  ? 91.896  117.510 81.227  1.00 83.36  ? 181  GLU A N     1 
ATOM   889   C  CA    . GLU A 1 163  ? 90.657  117.512 81.992  1.00 83.36  ? 181  GLU A CA    1 
ATOM   890   C  C     . GLU A 1 163  ? 90.771  118.245 83.322  1.00 83.36  ? 181  GLU A C     1 
ATOM   891   O  O     . GLU A 1 163  ? 89.740  118.545 83.933  1.00 83.36  ? 181  GLU A O     1 
ATOM   892   C  CB    . GLU A 1 163  ? 90.194  116.075 82.251  1.00 83.36  ? 181  GLU A CB    1 
ATOM   893   C  CG    . GLU A 1 163  ? 89.975  115.251 80.994  1.00 83.36  ? 181  GLU A CG    1 
ATOM   894   C  CD    . GLU A 1 163  ? 89.542  113.830 81.299  1.00 83.36  ? 181  GLU A CD    1 
ATOM   895   O  OE1   . GLU A 1 163  ? 89.423  113.487 82.495  1.00 83.36  ? 181  GLU A OE1   1 
ATOM   896   O  OE2   . GLU A 1 163  ? 89.321  113.056 80.344  1.00 83.36  ? 181  GLU A OE2   1 
ATOM   897   N  N     . GLY A 1 164  ? 91.985  118.540 83.781  1.00 70.86  ? 182  GLY A N     1 
ATOM   898   C  CA    . GLY A 1 164  ? 92.159  119.176 85.076  1.00 70.86  ? 182  GLY A CA    1 
ATOM   899   C  C     . GLY A 1 164  ? 91.644  118.349 86.231  1.00 70.86  ? 182  GLY A C     1 
ATOM   900   O  O     . GLY A 1 164  ? 91.175  118.909 87.228  1.00 70.86  ? 182  GLY A O     1 
ATOM   901   N  N     . GLU A 1 165  ? 91.715  117.026 86.122  1.00 72.61  ? 183  GLU A N     1 
ATOM   902   C  CA    . GLU A 1 165  ? 91.200  116.151 87.163  1.00 72.61  ? 183  GLU A CA    1 
ATOM   903   C  C     . GLU A 1 165  ? 92.085  116.208 88.403  1.00 72.61  ? 183  GLU A C     1 
ATOM   904   O  O     . GLU A 1 165  ? 93.301  116.404 88.320  1.00 72.61  ? 183  GLU A O     1 
ATOM   905   C  CB    . GLU A 1 165  ? 91.110  114.714 86.645  1.00 72.61  ? 183  GLU A CB    1 
ATOM   906   C  CG    . GLU A 1 165  ? 90.456  113.731 87.602  1.00 72.61  ? 183  GLU A CG    1 
ATOM   907   C  CD    . GLU A 1 165  ? 90.542  112.301 87.111  1.00 72.61  ? 183  GLU A CD    1 
ATOM   908   O  OE1   . GLU A 1 165  ? 91.061  112.084 85.997  1.00 72.61  ? 183  GLU A OE1   1 
ATOM   909   O  OE2   . GLU A 1 165  ? 90.093  111.392 87.841  1.00 72.61  ? 183  GLU A OE2   1 
ATOM   910   N  N     . ALA A 1 166  ? 91.458  116.035 89.568  1.00 67.53  ? 184  ALA A N     1 
ATOM   911   C  CA    . ALA A 1 166  ? 92.181  115.980 90.837  1.00 67.53  ? 184  ALA A CA    1 
ATOM   912   C  C     . ALA A 1 166  ? 92.859  114.616 90.938  1.00 67.53  ? 184  ALA A C     1 
ATOM   913   O  O     . ALA A 1 166  ? 92.370  113.679 91.573  1.00 67.53  ? 184  ALA A O     1 
ATOM   914   C  CB    . ALA A 1 166  ? 91.240  116.233 92.008  1.00 67.53  ? 184  ALA A CB    1 
ATOM   915   N  N     . VAL A 1 167  ? 94.014  114.512 90.289  1.00 60.42  ? 185  VAL A N     1 
ATOM   916   C  CA    . VAL A 1 167  ? 94.759  113.257 90.221  1.00 60.42  ? 185  VAL A CA    1 
ATOM   917   C  C     . VAL A 1 167  ? 95.601  113.089 91.480  1.00 60.42  ? 185  VAL A C     1 
ATOM   918   O  O     . VAL A 1 167  ? 96.459  113.935 91.770  1.00 60.42  ? 185  VAL A O     1 
ATOM   919   C  CB    . VAL A 1 167  ? 95.640  113.204 88.964  1.00 60.42  ? 185  VAL A CB    1 
ATOM   920   C  CG1   . VAL A 1 167  ? 96.327  111.853 88.860  1.00 60.42  ? 185  VAL A CG1   1 
ATOM   921   C  CG2   . VAL A 1 167  ? 94.810  113.486 87.723  1.00 60.42  ? 185  VAL A CG2   1 
ATOM   922   N  N     . PRO A 1 168  ? 95.398  112.021 92.252  1.00 57.07  ? 186  PRO A N     1 
ATOM   923   C  CA    . PRO A 1 168  ? 96.257  111.771 93.420  1.00 57.07  ? 186  PRO A CA    1 
ATOM   924   C  C     . PRO A 1 168  ? 97.609  111.229 92.977  1.00 57.07  ? 186  PRO A C     1 
ATOM   925   O  O     . PRO A 1 168  ? 97.703  110.128 92.431  1.00 57.07  ? 186  PRO A O     1 
ATOM   926   C  CB    . PRO A 1 168  ? 95.465  110.738 94.228  1.00 57.07  ? 186  PRO A CB    1 
ATOM   927   C  CG    . PRO A 1 168  ? 94.640  110.025 93.207  1.00 57.07  ? 186  PRO A CG    1 
ATOM   928   C  CD    . PRO A 1 168  ? 94.305  111.039 92.144  1.00 57.07  ? 186  PRO A CD    1 
ATOM   929   N  N     . VAL A 1 169  ? 98.658  112.012 93.214  1.00 47.23  ? 187  VAL A N     1 
ATOM   930   C  CA    . VAL A 1 169  ? 100.004 111.685 92.762  1.00 47.23  ? 187  VAL A CA    1 
ATOM   931   C  C     . VAL A 1 169  ? 100.943 111.733 93.958  1.00 47.23  ? 187  VAL A C     1 
ATOM   932   O  O     . VAL A 1 169  ? 100.834 112.627 94.804  1.00 47.23  ? 187  VAL A O     1 
ATOM   933   C  CB    . VAL A 1 169  ? 100.487 112.650 91.660  1.00 47.23  ? 187  VAL A CB    1 
ATOM   934   C  CG1   . VAL A 1 169  ? 101.843 112.220 91.128  1.00 47.23  ? 187  VAL A CG1   1 
ATOM   935   C  CG2   . VAL A 1 169  ? 99.471  112.725 90.534  1.00 47.23  ? 187  VAL A CG2   1 
ATOM   936   N  N     . ALA A 1 170  ? 101.840 110.754 94.044  1.00 43.00  ? 188  ALA A N     1 
ATOM   937   C  CA    . ALA A 1 170  ? 102.951 110.785 94.986  1.00 43.00  ? 188  ALA A CA    1 
ATOM   938   C  C     . ALA A 1 170  ? 104.294 110.951 94.291  1.00 43.00  ? 188  ALA A C     1 
ATOM   939   O  O     . ALA A 1 170  ? 105.208 111.562 94.850  1.00 43.00  ? 188  ALA A O     1 
ATOM   940   C  CB    . ALA A 1 170  ? 102.969 109.510 95.833  1.00 43.00  ? 188  ALA A CB    1 
ATOM   941   N  N     . ILE A 1 171  ? 104.422 110.425 93.077  1.00 47.76  ? 189  ILE A N     1 
ATOM   942   C  CA    . ILE A 1 171  ? 105.663 110.488 92.311  1.00 47.76  ? 189  ILE A CA    1 
ATOM   943   C  C     . ILE A 1 171  ? 105.341 110.933 90.890  1.00 47.76  ? 189  ILE A C     1 
ATOM   944   O  O     . ILE A 1 171  ? 104.401 110.407 90.276  1.00 47.76  ? 189  ILE A O     1 
ATOM   945   C  CB    . ILE A 1 171  ? 106.389 109.134 92.324  1.00 47.76  ? 189  ILE A CB    1 
ATOM   946   C  CG1   . ILE A 1 171  ? 105.390 107.995 92.101  1.00 47.76  ? 189  ILE A CG1   1 
ATOM   947   C  CG2   . ILE A 1 171  ? 107.142 108.941 93.634  1.00 47.76  ? 189  ILE A CG2   1 
ATOM   948   C  CD1   . ILE A 1 171  ? 105.991 106.615 92.245  1.00 47.76  ? 189  ILE A CD1   1 
ATOM   949   N  N     . PRO A 1 172  ? 106.078 111.899 90.334  1.00 47.07  ? 190  PRO A N     1 
ATOM   950   C  CA    . PRO A 1 172  ? 105.794 112.337 88.957  1.00 47.07  ? 190  PRO A CA    1 
ATOM   951   C  C     . PRO A 1 172  ? 105.883 111.224 87.930  1.00 47.07  ? 190  PRO A C     1 
ATOM   952   O  O     . PRO A 1 172  ? 105.152 111.261 86.932  1.00 47.07  ? 190  PRO A O     1 
ATOM   953   C  CB    . PRO A 1 172  ? 106.857 113.417 88.713  1.00 47.07  ? 190  PRO A CB    1 
ATOM   954   C  CG    . PRO A 1 172  ? 107.179 113.929 90.065  1.00 47.07  ? 190  PRO A CG    1 
ATOM   955   C  CD    . PRO A 1 172  ? 107.102 112.738 90.977  1.00 47.07  ? 190  PRO A CD    1 
ATOM   956   N  N     . GLU A 1 173  ? 106.759 110.239 88.141  1.00 54.68  ? 191  GLU A N     1 
ATOM   957   C  CA    . GLU A 1 173  ? 106.901 109.096 87.237  1.00 54.68  ? 191  GLU A CA    1 
ATOM   958   C  C     . GLU A 1 173  ? 107.266 109.549 85.824  1.00 54.68  ? 191  GLU A C     1 
ATOM   959   O  O     . GLU A 1 173  ? 106.826 108.969 84.830  1.00 54.68  ? 191  GLU A O     1 
ATOM   960   C  CB    . GLU A 1 173  ? 105.628 108.242 87.227  1.00 54.68  ? 191  GLU A CB    1 
ATOM   961   C  CG    . GLU A 1 173  ? 105.818 106.807 86.758  1.00 54.68  ? 191  GLU A CG    1 
ATOM   962   C  CD    . GLU A 1 173  ? 106.375 105.909 87.841  1.00 54.68  ? 191  GLU A CD    1 
ATOM   963   O  OE1   . GLU A 1 173  ? 106.362 106.320 89.020  1.00 54.68  ? 191  GLU A OE1   1 
ATOM   964   O  OE2   . GLU A 1 173  ? 106.826 104.792 87.514  1.00 54.68  ? 191  GLU A OE2   1 
ATOM   965   N  N     . GLU A 1 174  ? 108.074 110.602 85.729  1.00 47.49  ? 192  GLU A N     1 
ATOM   966   C  CA    . GLU A 1 174  ? 108.507 111.130 84.445  1.00 47.49  ? 192  GLU A CA    1 
ATOM   967   C  C     . GLU A 1 174  ? 110.005 111.387 84.467  1.00 47.49  ? 192  GLU A C     1 
ATOM   968   O  O     . GLU A 1 174  ? 110.580 111.730 85.503  1.00 47.49  ? 192  GLU A O     1 
ATOM   969   C  CB    . GLU A 1 174  ? 107.764 112.420 84.079  1.00 47.49  ? 192  GLU A CB    1 
ATOM   970   C  CG    . GLU A 1 174  ? 106.256 112.263 83.978  1.00 47.49  ? 192  GLU A CG    1 
ATOM   971   C  CD    . GLU A 1 174  ? 105.835 111.233 82.949  1.00 47.49  ? 192  GLU A CD    1 
ATOM   972   O  OE1   . GLU A 1 174  ? 106.466 111.163 81.874  1.00 47.49  ? 192  GLU A OE1   1 
ATOM   973   O  OE2   . GLU A 1 174  ? 104.870 110.489 83.220  1.00 47.49  ? 192  GLU A OE2   1 
ATOM   974   N  N     . ARG A 1 175  ? 110.630 111.222 83.306  1.00 36.40  ? 193  ARG A N     1 
ATOM   975   C  CA    . ARG A 1 175  ? 112.071 111.358 83.164  1.00 36.40  ? 193  ARG A CA    1 
ATOM   976   C  C     . ARG A 1 175  ? 112.527 112.795 82.956  1.00 36.40  ? 193  ARG A C     1 
ATOM   977   O  O     . ARG A 1 175  ? 113.735 113.036 82.879  1.00 36.40  ? 193  ARG A O     1 
ATOM   978   C  CB    . ARG A 1 175  ? 112.567 110.501 81.997  1.00 36.40  ? 193  ARG A CB    1 
ATOM   979   C  CG    . ARG A 1 175  ? 112.800 109.039 82.332  1.00 36.40  ? 193  ARG A CG    1 
ATOM   980   C  CD    . ARG A 1 175  ? 113.339 108.305 81.115  1.00 36.40  ? 193  ARG A CD    1 
ATOM   981   N  NE    . ARG A 1 175  ? 114.135 109.192 80.274  1.00 36.40  ? 193  ARG A NE    1 
ATOM   982   C  CZ    . ARG A 1 175  ? 114.721 108.830 79.141  1.00 36.40  ? 193  ARG A CZ    1 
ATOM   983   N  NH1   . ARG A 1 175  ? 114.650 107.588 78.691  1.00 36.40  ? 193  ARG A NH1   1 
ATOM   984   N  NH2   . ARG A 1 175  ? 115.393 109.738 78.441  1.00 36.40  ? 193  ARG A NH2   1 
ATOM   985   N  N     . ALA A 1 176  ? 111.607 113.753 82.858  1.00 34.78  ? 194  ALA A N     1 
ATOM   986   C  CA    . ALA A 1 176  ? 111.992 115.140 82.605  1.00 34.78  ? 194  ALA A CA    1 
ATOM   987   C  C     . ALA A 1 176  ? 110.961 116.062 83.238  1.00 34.78  ? 194  ALA A C     1 
ATOM   988   O  O     . ALA A 1 176  ? 109.804 116.088 82.807  1.00 34.78  ? 194  ALA A O     1 
ATOM   989   C  CB    . ALA A 1 176  ? 112.117 115.406 81.108  1.00 34.78  ? 194  ALA A CB    1 
ATOM   990   N  N     . LEU A 1 177  ? 111.349 116.804 84.276  1.00 30.69  ? 195  LEU A N     1 
ATOM   991   C  CA    . LEU A 1 177  ? 110.417 117.673 84.984  1.00 30.69  ? 195  LEU A CA    1 
ATOM   992   C  C     . LEU A 1 177  ? 111.013 119.030 85.294  1.00 30.69  ? 195  LEU A C     1 
ATOM   993   O  O     . LEU A 1 177  ? 111.904 119.107 86.136  1.00 30.69  ? 195  LEU A O     1 
ATOM   994   C  CB    . LEU A 1 177  ? 110.057 117.031 86.310  1.00 30.69  ? 195  LEU A CB    1 
ATOM   995   C  CG    . LEU A 1 177  ? 109.683 115.554 86.290  1.00 30.69  ? 195  LEU A CG    1 
ATOM   996   C  CD1   . LEU A 1 177  ? 109.858 114.945 87.669  1.00 30.69  ? 195  LEU A CD1   1 
ATOM   997   C  CD2   . LEU A 1 177  ? 108.260 115.373 85.795  1.00 30.69  ? 195  LEU A CD2   1 
ATOM   998   N  N     . VAL A 1 178  ? 110.559 120.114 84.656  1.00 28.12  ? 196  VAL A N     1 
ATOM   999   C  CA    . VAL A 1 178  ? 111.067 121.442 85.060  1.00 28.12  ? 196  VAL A CA    1 
ATOM   1000  C  C     . VAL A 1 178  ? 110.558 121.643 86.480  1.00 28.12  ? 196  VAL A C     1 
ATOM   1001  O  O     . VAL A 1 178  ? 109.533 121.076 86.837  1.00 28.12  ? 196  VAL A O     1 
ATOM   1002  C  CB    . VAL A 1 178  ? 110.701 122.572 84.097  1.00 28.12  ? 196  VAL A CB    1 
ATOM   1003  C  CG1   . VAL A 1 178  ? 111.486 123.826 84.445  1.00 28.12  ? 196  VAL A CG1   1 
ATOM   1004  C  CG2   . VAL A 1 178  ? 110.997 122.150 82.670  1.00 28.12  ? 196  VAL A CG2   1 
ATOM   1005  N  N     . PHE A 1 179  ? 111.234 122.437 87.305  1.00 28.48  ? 197  PHE A N     1 
ATOM   1006  C  CA    . PHE A 1 179  ? 110.857 122.485 88.706  1.00 28.48  ? 197  PHE A CA    1 
ATOM   1007  C  C     . PHE A 1 179  ? 111.091 123.873 89.276  1.00 28.48  ? 197  PHE A C     1 
ATOM   1008  O  O     . PHE A 1 179  ? 111.944 124.625 88.799  1.00 28.48  ? 197  PHE A O     1 
ATOM   1009  C  CB    . PHE A 1 179  ? 111.655 121.458 89.515  1.00 28.48  ? 197  PHE A CB    1 
ATOM   1010  C  CG    . PHE A 1 179  ? 110.875 120.814 90.615  1.00 28.48  ? 197  PHE A CG    1 
ATOM   1011  C  CD1   . PHE A 1 179  ? 110.653 121.476 91.806  1.00 28.48  ? 197  PHE A CD1   1 
ATOM   1012  C  CD2   . PHE A 1 179  ? 110.367 119.541 90.460  1.00 28.48  ? 197  PHE A CD2   1 
ATOM   1013  C  CE1   . PHE A 1 179  ? 109.932 120.882 92.818  1.00 28.48  ? 197  PHE A CE1   1 
ATOM   1014  C  CE2   . PHE A 1 179  ? 109.651 118.944 91.470  1.00 28.48  ? 197  PHE A CE2   1 
ATOM   1015  C  CZ    . PHE A 1 179  ? 109.434 119.617 92.651  1.00 28.48  ? 197  PHE A CZ    1 
ATOM   1016  N  N     . ASP A 1 180  ? 110.311 124.207 90.300  1.00 31.12  ? 198  ASP A N     1 
ATOM   1017  C  CA    . ASP A 1 180  ? 110.564 125.403 91.097  1.00 31.12  ? 198  ASP A CA    1 
ATOM   1018  C  C     . ASP A 1 180  ? 109.920 125.206 92.457  1.00 31.12  ? 198  ASP A C     1 
ATOM   1019  O  O     . ASP A 1 180  ? 108.712 124.964 92.539  1.00 31.12  ? 198  ASP A O     1 
ATOM   1020  C  CB    . ASP A 1 180  ? 110.023 126.649 90.412  1.00 31.12  ? 198  ASP A CB    1 
ATOM   1021  C  CG    . ASP A 1 180  ? 110.947 127.835 90.561  1.00 31.12  ? 198  ASP A CG    1 
ATOM   1022  O  OD1   . ASP A 1 180  ? 112.117 127.732 90.135  1.00 31.12  ? 198  ASP A OD1   1 
ATOM   1023  O  OD2   . ASP A 1 180  ? 110.506 128.870 91.101  1.00 31.12  ? 198  ASP A OD2   1 
ATOM   1024  N  N     . VAL A 1 181  ? 110.720 125.300 93.514  1.00 32.58  ? 199  VAL A N     1 
ATOM   1025  C  CA    . VAL A 1 181  ? 110.262 125.089 94.882  1.00 32.58  ? 199  VAL A CA    1 
ATOM   1026  C  C     . VAL A 1 181  ? 110.079 126.441 95.548  1.00 32.58  ? 199  VAL A C     1 
ATOM   1027  O  O     . VAL A 1 181  ? 110.928 127.331 95.416  1.00 32.58  ? 199  VAL A O     1 
ATOM   1028  C  CB    . VAL A 1 181  ? 111.254 124.221 95.678  1.00 32.58  ? 199  VAL A CB    1 
ATOM   1029  C  CG1   . VAL A 1 181  ? 110.640 123.786 96.997  1.00 32.58  ? 199  VAL A CG1   1 
ATOM   1030  C  CG2   . VAL A 1 181  ? 111.685 123.020 94.866  1.00 32.58  ? 199  VAL A CG2   1 
ATOM   1031  N  N     . GLU A 1 182  ? 108.968 126.599 96.261  1.00 40.77  ? 200  GLU A N     1 
ATOM   1032  C  CA    . GLU A 1 182  ? 108.670 127.818 96.998  1.00 40.77  ? 200  GLU A CA    1 
ATOM   1033  C  C     . GLU A 1 182  ? 108.749 127.534 98.491  1.00 40.77  ? 200  GLU A C     1 
ATOM   1034  O  O     . GLU A 1 182  ? 108.076 126.628 98.991  1.00 40.77  ? 200  GLU A O     1 
ATOM   1035  C  CB    . GLU A 1 182  ? 107.286 128.351 96.626  1.00 40.77  ? 200  GLU A CB    1 
ATOM   1036  C  CG    . GLU A 1 182  ? 107.074 128.554 95.132  1.00 40.77  ? 200  GLU A CG    1 
ATOM   1037  C  CD    . GLU A 1 182  ? 107.876 129.712 94.566  1.00 40.77  ? 200  GLU A CD    1 
ATOM   1038  O  OE1   . GLU A 1 182  ? 108.469 130.476 95.354  1.00 40.77  ? 200  GLU A OE1   1 
ATOM   1039  O  OE2   . GLU A 1 182  ? 107.909 129.860 93.327  1.00 40.77  ? 200  GLU A OE2   1 
ATOM   1040  N  N     . VAL A 1 183  ? 109.571 128.309 99.195  1.00 44.51  ? 201  VAL A N     1 
ATOM   1041  C  CA    . VAL A 1 183  ? 109.813 128.126 100.622 1.00 44.51  ? 201  VAL A CA    1 
ATOM   1042  C  C     . VAL A 1 183  ? 109.602 129.459 101.325 1.00 44.51  ? 201  VAL A C     1 
ATOM   1043  O  O     . VAL A 1 183  ? 110.179 130.475 100.922 1.00 44.51  ? 201  VAL A O     1 
ATOM   1044  C  CB    . VAL A 1 183  ? 111.233 127.594 100.896 1.00 44.51  ? 201  VAL A CB    1 
ATOM   1045  C  CG1   . VAL A 1 183  ? 111.457 127.414 102.386 1.00 44.51  ? 201  VAL A CG1   1 
ATOM   1046  C  CG2   . VAL A 1 183  ? 111.468 126.287 100.157 1.00 44.51  ? 201  VAL A CG2   1 
ATOM   1047  N  N     . CYS A 1 184  ? 108.785 129.455 102.376 1.00 45.85  ? 202  CYS A N     1 
ATOM   1048  C  CA    . CYS A 1 184  ? 108.553 130.653 103.178 1.00 45.85  ? 202  CYS A CA    1 
ATOM   1049  C  C     . CYS A 1 184  ? 109.756 130.872 104.086 1.00 45.85  ? 202  CYS A C     1 
ATOM   1050  O  O     . CYS A 1 184  ? 110.018 130.065 104.983 1.00 45.85  ? 202  CYS A O     1 
ATOM   1051  C  CB    . CYS A 1 184  ? 107.270 130.515 103.990 1.00 45.85  ? 202  CYS A CB    1 
ATOM   1052  S  SG    . CYS A 1 184  ? 106.960 131.878 105.131 1.00 45.85  ? 202  CYS A SG    1 
ATOM   1053  N  N     . LEU A 1 185  ? 110.480 131.970 103.862 1.00 45.30  ? 203  LEU A N     1 
ATOM   1054  C  CA    . LEU A 1 185  ? 111.732 132.194 104.580 1.00 45.30  ? 203  LEU A CA    1 
ATOM   1055  C  C     . LEU A 1 185  ? 111.499 132.322 106.081 1.00 45.30  ? 203  LEU A C     1 
ATOM   1056  O  O     . LEU A 1 185  ? 112.275 131.789 106.883 1.00 45.30  ? 203  LEU A O     1 
ATOM   1057  C  CB    . LEU A 1 185  ? 112.429 133.441 104.030 1.00 45.30  ? 203  LEU A CB    1 
ATOM   1058  C  CG    . LEU A 1 185  ? 113.903 133.694 104.365 1.00 45.30  ? 203  LEU A CG    1 
ATOM   1059  C  CD1   . LEU A 1 185  ? 114.526 134.579 103.302 1.00 45.30  ? 203  LEU A CD1   1 
ATOM   1060  C  CD2   . LEU A 1 185  ? 114.079 134.332 105.736 1.00 45.30  ? 203  LEU A CD2   1 
ATOM   1061  N  N     . ALA A 1 186  ? 110.440 133.027 106.480 1.00 43.56  ? 204  ALA A N     1 
ATOM   1062  C  CA    . ALA A 1 186  ? 110.223 133.301 107.897 1.00 43.56  ? 204  ALA A CA    1 
ATOM   1063  C  C     . ALA A 1 186  ? 109.893 132.029 108.670 1.00 43.56  ? 204  ALA A C     1 
ATOM   1064  O  O     . ALA A 1 186  ? 110.485 131.760 109.722 1.00 43.56  ? 204  ALA A O     1 
ATOM   1065  C  CB    . ALA A 1 186  ? 109.114 134.338 108.064 1.00 43.56  ? 204  ALA A CB    1 
ATOM   1066  N  N     . GLU A 1 187  ? 108.948 131.232 108.165 1.00 44.93  ? 205  GLU A N     1 
ATOM   1067  C  CA    . GLU A 1 187  ? 108.475 130.076 108.922 1.00 44.93  ? 205  GLU A CA    1 
ATOM   1068  C  C     . GLU A 1 187  ? 109.556 129.009 109.056 1.00 44.93  ? 205  GLU A C     1 
ATOM   1069  O  O     . GLU A 1 187  ? 109.711 128.411 110.126 1.00 44.93  ? 205  GLU A O     1 
ATOM   1070  C  CB    . GLU A 1 187  ? 107.220 129.501 108.266 1.00 44.93  ? 205  GLU A CB    1 
ATOM   1071  C  CG    . GLU A 1 187  ? 106.496 128.462 109.107 1.00 44.93  ? 205  GLU A CG    1 
ATOM   1072  C  CD    . GLU A 1 187  ? 106.997 127.053 108.862 1.00 44.93  ? 205  GLU A CD    1 
ATOM   1073  O  OE1   . GLU A 1 187  ? 107.710 126.837 107.859 1.00 44.93  ? 205  GLU A OE1   1 
ATOM   1074  O  OE2   . GLU A 1 187  ? 106.676 126.159 109.673 1.00 44.93  ? 205  GLU A OE2   1 
ATOM   1075  N  N     . GLY A 1 188  ? 110.303 128.750 107.991 1.00 41.59  ? 206  GLY A N     1 
ATOM   1076  C  CA    . GLY A 1 188  ? 111.374 127.776 108.057 1.00 41.59  ? 206  GLY A CA    1 
ATOM   1077  C  C     . GLY A 1 188  ? 111.831 127.380 106.671 1.00 41.59  ? 206  GLY A C     1 
ATOM   1078  O  O     . GLY A 1 188  ? 111.227 127.747 105.660 1.00 41.59  ? 206  GLY A O     1 
ATOM   1079  N  N     . THR A 1 189  ? 112.913 126.601 106.644 1.00 33.86  ? 207  THR A N     1 
ATOM   1080  C  CA    . THR A 1 189  ? 113.479 126.151 105.378 1.00 33.86  ? 207  THR A CA    1 
ATOM   1081  C  C     . THR A 1 189  ? 112.698 125.004 104.753 1.00 33.86  ? 207  THR A C     1 
ATOM   1082  O  O     . THR A 1 189  ? 113.002 124.618 103.621 1.00 33.86  ? 207  THR A O     1 
ATOM   1083  C  CB    . THR A 1 189  ? 114.938 125.730 105.562 1.00 33.86  ? 207  THR A CB    1 
ATOM   1084  O  OG1   . THR A 1 189  ? 115.029 124.747 106.600 1.00 33.86  ? 207  THR A OG1   1 
ATOM   1085  C  CG2   . THR A 1 189  ? 115.801 126.926 105.926 1.00 33.86  ? 207  THR A CG2   1 
ATOM   1086  N  N     . CYS A 1 190  ? 111.719 124.449 105.458 1.00 41.48  ? 208  CYS A N     1 
ATOM   1087  C  CA    . CYS A 1 190  ? 110.882 123.410 104.879 1.00 41.48  ? 208  CYS A CA    1 
ATOM   1088  C  C     . CYS A 1 190  ? 110.058 123.986 103.728 1.00 41.48  ? 208  CYS A C     1 
ATOM   1089  O  O     . CYS A 1 190  ? 109.561 125.114 103.824 1.00 41.48  ? 208  CYS A O     1 
ATOM   1090  C  CB    . CYS A 1 190  ? 109.962 122.820 105.946 1.00 41.48  ? 208  CYS A CB    1 
ATOM   1091  S  SG    . CYS A 1 190  ? 109.031 121.359 105.442 1.00 41.48  ? 208  CYS A SG    1 
ATOM   1092  N  N     . PRO A 1 191  ? 109.895 123.244 102.631 1.00 35.19  ? 209  PRO A N     1 
ATOM   1093  C  CA    . PRO A 1 191  ? 109.157 123.779 101.482 1.00 35.19  ? 209  PRO A CA    1 
ATOM   1094  C  C     . PRO A 1 191  ? 107.699 124.050 101.813 1.00 35.19  ? 209  PRO A C     1 
ATOM   1095  O  O     . PRO A 1 191  ? 107.095 123.392 102.662 1.00 35.19  ? 209  PRO A O     1 
ATOM   1096  C  CB    . PRO A 1 191  ? 109.286 122.671 100.429 1.00 35.19  ? 209  PRO A CB    1 
ATOM   1097  C  CG    . PRO A 1 191  ? 110.469 121.888 100.844 1.00 35.19  ? 209  PRO A CG    1 
ATOM   1098  C  CD    . PRO A 1 191  ? 110.479 121.926 102.337 1.00 35.19  ? 209  PRO A CD    1 
ATOM   1099  N  N     . THR A 1 192  ? 107.138 125.050 101.136 1.00 38.26  ? 210  THR A N     1 
ATOM   1100  C  CA    . THR A 1 192  ? 105.704 125.309 101.214 1.00 38.26  ? 210  THR A CA    1 
ATOM   1101  C  C     . THR A 1 192  ? 104.963 124.604 100.082 1.00 38.26  ? 210  THR A C     1 
ATOM   1102  O  O     . THR A 1 192  ? 104.101 123.754 100.327 1.00 38.26  ? 210  THR A O     1 
ATOM   1103  C  CB    . THR A 1 192  ? 105.440 126.818 101.178 1.00 38.26  ? 210  THR A CB    1 
ATOM   1104  O  OG1   . THR A 1 192  ? 105.926 127.362 99.946  1.00 38.26  ? 210  THR A OG1   1 
ATOM   1105  C  CG2   . THR A 1 192  ? 106.146 127.500 102.330 1.00 38.26  ? 210  THR A CG2   1 
ATOM   1106  N  N     . LEU A 1 193  ? 105.310 124.931 98.840  1.00 38.04  ? 211  LEU A N     1 
ATOM   1107  C  CA    . LEU A 1 193  ? 104.669 124.346 97.674  1.00 38.04  ? 211  LEU A CA    1 
ATOM   1108  C  C     . LEU A 1 193  ? 105.634 124.416 96.499  1.00 38.04  ? 211  LEU A C     1 
ATOM   1109  O  O     . LEU A 1 193  ? 106.652 125.111 96.543  1.00 38.04  ? 211  LEU A O     1 
ATOM   1110  C  CB    . LEU A 1 193  ? 103.343 125.049 97.353  1.00 38.04  ? 211  LEU A CB    1 
ATOM   1111  C  CG    . LEU A 1 193  ? 103.317 126.581 97.407  1.00 38.04  ? 211  LEU A CG    1 
ATOM   1112  C  CD1   . LEU A 1 193  ? 103.816 127.210 96.113  1.00 38.04  ? 211  LEU A CD1   1 
ATOM   1113  C  CD2   . LEU A 1 193  ? 101.921 127.083 97.745  1.00 38.04  ? 211  LEU A CD2   1 
ATOM   1114  N  N     . ALA A 1 194  ? 105.305 123.678 95.441  1.00 33.50  ? 212  ALA A N     1 
ATOM   1115  C  CA    . ALA A 1 194  ? 106.129 123.671 94.242  1.00 33.50  ? 212  ALA A CA    1 
ATOM   1116  C  C     . ALA A 1 194  ? 105.268 123.300 93.047  1.00 33.50  ? 212  ALA A C     1 
ATOM   1117  O  O     . ALA A 1 194  ? 104.376 122.455 93.147  1.00 33.50  ? 212  ALA A O     1 
ATOM   1118  C  CB    . ALA A 1 194  ? 107.302 122.698 94.375  1.00 33.50  ? 212  ALA A CB    1 
ATOM   1119  N  N     . VAL A 1 195  ? 105.551 123.939 91.915  1.00 34.62  ? 213  VAL A N     1 
ATOM   1120  C  CA    . VAL A 1 195  ? 104.863 123.683 90.655  1.00 34.62  ? 213  VAL A CA    1 
ATOM   1121  C  C     . VAL A 1 195  ? 105.889 123.168 89.657  1.00 34.62  ? 213  VAL A C     1 
ATOM   1122  O  O     . VAL A 1 195  ? 106.943 123.786 89.471  1.00 34.62  ? 213  VAL A O     1 
ATOM   1123  C  CB    . VAL A 1 195  ? 104.165 124.948 90.121  1.00 34.62  ? 213  VAL A CB    1 
ATOM   1124  C  CG1   . VAL A 1 195  ? 103.266 124.607 88.943  1.00 34.62  ? 213  VAL A CG1   1 
ATOM   1125  C  CG2   . VAL A 1 195  ? 103.374 125.629 91.225  1.00 34.62  ? 213  VAL A CG2   1 
ATOM   1126  N  N     . ALA A 1 196  ? 105.584 122.039 89.022  1.00 33.95  ? 214  ALA A N     1 
ATOM   1127  C  CA    . ALA A 1 196  ? 106.494 121.399 88.086  1.00 33.95  ? 214  ALA A CA    1 
ATOM   1128  C  C     . ALA A 1 196  ? 105.754 121.056 86.802  1.00 33.95  ? 214  ALA A C     1 
ATOM   1129  O  O     . ALA A 1 196  ? 104.525 120.971 86.777  1.00 33.95  ? 214  ALA A O     1 
ATOM   1130  C  CB    . ALA A 1 196  ? 107.113 120.132 88.685  1.00 33.95  ? 214  ALA A CB    1 
ATOM   1131  N  N     . ILE A 1 197  ? 106.512 120.878 85.721  1.00 36.91  ? 215  ILE A N     1 
ATOM   1132  C  CA    . ILE A 1 197  ? 105.952 120.474 84.438  1.00 36.91  ? 215  ILE A CA    1 
ATOM   1133  C  C     . ILE A 1 197  ? 106.769 119.331 83.854  1.00 36.91  ? 215  ILE A C     1 
ATOM   1134  O  O     . ILE A 1 197  ? 108.004 119.369 83.848  1.00 36.91  ? 215  ILE A O     1 
ATOM   1135  C  CB    . ILE A 1 197  ? 105.883 121.644 83.433  1.00 36.91  ? 215  ILE A CB    1 
ATOM   1136  C  CG1   . ILE A 1 197  ? 107.273 122.160 83.086  1.00 36.91  ? 215  ILE A CG1   1 
ATOM   1137  C  CG2   . ILE A 1 197  ? 105.072 122.778 83.988  1.00 36.91  ? 215  ILE A CG2   1 
ATOM   1138  C  CD1   . ILE A 1 197  ? 107.246 123.290 82.109  1.00 36.91  ? 215  ILE A CD1   1 
ATOM   1139  N  N     . SER A 1 198  ? 106.074 118.303 83.379  1.00 42.68  ? 216  SER A N     1 
ATOM   1140  C  CA    . SER A 1 198  ? 106.647 117.340 82.462  1.00 42.68  ? 216  SER A CA    1 
ATOM   1141  C  C     . SER A 1 198  ? 105.897 117.435 81.141  1.00 42.68  ? 216  SER A C     1 
ATOM   1142  O  O     . SER A 1 198  ? 104.759 117.917 81.123  1.00 42.68  ? 216  SER A O     1 
ATOM   1143  C  CB    . SER A 1 198  ? 106.562 115.905 83.007  1.00 42.68  ? 216  SER A CB    1 
ATOM   1144  O  OG    . SER A 1 198  ? 105.248 115.388 82.901  1.00 42.68  ? 216  SER A OG    1 
ATOM   1145  N  N     . PRO A 1 199  ? 106.509 117.033 80.020  1.00 46.79  ? 217  PRO A N     1 
ATOM   1146  C  CA    . PRO A 1 199  ? 105.787 117.069 78.740  1.00 46.79  ? 217  PRO A CA    1 
ATOM   1147  C  C     . PRO A 1 199  ? 104.411 116.432 78.841  1.00 46.79  ? 217  PRO A C     1 
ATOM   1148  O  O     . PRO A 1 199  ? 104.281 115.281 79.272  1.00 46.79  ? 217  PRO A O     1 
ATOM   1149  C  CB    . PRO A 1 199  ? 106.707 116.290 77.789  1.00 46.79  ? 217  PRO A CB    1 
ATOM   1150  C  CG    . PRO A 1 199  ? 107.756 115.648 78.666  1.00 46.79  ? 217  PRO A CG    1 
ATOM   1151  C  CD    . PRO A 1 199  ? 107.883 116.539 79.852  1.00 46.79  ? 217  PRO A CD    1 
ATOM   1152  N  N     . SER A 1 200  ? 103.382 117.208 78.489  1.00 52.12  ? 218  SER A N     1 
ATOM   1153  C  CA    . SER A 1 200  ? 101.980 116.798 78.510  1.00 52.12  ? 218  SER A CA    1 
ATOM   1154  C  C     . SER A 1 200  ? 101.442 116.662 79.931  1.00 52.12  ? 218  SER A C     1 
ATOM   1155  O  O     . SER A 1 200  ? 100.504 115.894 80.166  1.00 52.12  ? 218  SER A O     1 
ATOM   1156  C  CB    . SER A 1 200  ? 101.773 115.489 77.741  1.00 52.12  ? 218  SER A CB    1 
ATOM   1157  O  OG    . SER A 1 200  ? 102.283 114.382 78.465  1.00 52.12  ? 218  SER A OG    1 
ATOM   1158  N  N     . ALA A 1 201  ? 102.015 117.394 80.883  1.00 48.75  ? 219  ALA A N     1 
ATOM   1159  C  CA    . ALA A 1 201  ? 101.494 117.387 82.246  1.00 48.75  ? 219  ALA A CA    1 
ATOM   1160  C  C     . ALA A 1 201  ? 101.898 118.677 82.947  1.00 48.75  ? 219  ALA A C     1 
ATOM   1161  O  O     . ALA A 1 201  ? 102.860 119.347 82.560  1.00 48.75  ? 219  ALA A O     1 
ATOM   1162  C  CB    . ALA A 1 201  ? 101.988 116.169 83.030  1.00 48.75  ? 219  ALA A CB    1 
ATOM   1163  N  N     . TRP A 1 202  ? 101.138 119.018 83.988  1.00 44.03  ? 220  TRP A N     1 
ATOM   1164  C  CA    . TRP A 1 202  ? 101.471 120.093 84.915  1.00 44.03  ? 220  TRP A CA    1 
ATOM   1165  C  C     . TRP A 1 202  ? 101.377 119.551 86.334  1.00 44.03  ? 220  TRP A C     1 
ATOM   1166  O  O     . TRP A 1 202  ? 100.383 118.913 86.690  1.00 44.03  ? 220  TRP A O     1 
ATOM   1167  C  CB    . TRP A 1 202  ? 100.544 121.294 84.732  1.00 44.03  ? 220  TRP A CB    1 
ATOM   1168  C  CG    . TRP A 1 202  ? 101.060 122.283 83.741  1.00 44.03  ? 220  TRP A CG    1 
ATOM   1169  C  CD1   . TRP A 1 202  ? 100.942 122.223 82.386  1.00 44.03  ? 220  TRP A CD1   1 
ATOM   1170  C  CD2   . TRP A 1 202  ? 101.785 123.484 84.028  1.00 44.03  ? 220  TRP A CD2   1 
ATOM   1171  N  NE1   . TRP A 1 202  ? 101.549 123.311 81.809  1.00 44.03  ? 220  TRP A NE1   1 
ATOM   1172  C  CE2   . TRP A 1 202  ? 102.074 124.101 82.796  1.00 44.03  ? 220  TRP A CE2   1 
ATOM   1173  C  CE3   . TRP A 1 202  ? 102.215 124.099 85.207  1.00 44.03  ? 220  TRP A CE3   1 
ATOM   1174  C  CZ2   . TRP A 1 202  ? 102.776 125.300 82.709  1.00 44.03  ? 220  TRP A CZ2   1 
ATOM   1175  C  CZ3   . TRP A 1 202  ? 102.916 125.288 85.118  1.00 44.03  ? 220  TRP A CZ3   1 
ATOM   1176  C  CH2   . TRP A 1 202  ? 103.187 125.877 83.877  1.00 44.03  ? 220  TRP A CH2   1 
ATOM   1177  N  N     . TYR A 1 203  ? 102.410 119.800 87.138  1.00 41.04  ? 221  TYR A N     1 
ATOM   1178  C  CA    . TYR A 1 203  ? 102.554 119.179 88.447  1.00 41.04  ? 221  TYR A CA    1 
ATOM   1179  C  C     . TYR A 1 203  ? 102.552 120.222 89.554  1.00 41.04  ? 221  TYR A C     1 
ATOM   1180  O  O     . TYR A 1 203  ? 102.977 121.364 89.358  1.00 41.04  ? 221  TYR A O     1 
ATOM   1181  C  CB    . TYR A 1 203  ? 103.849 118.364 88.542  1.00 41.04  ? 221  TYR A CB    1 
ATOM   1182  C  CG    . TYR A 1 203  ? 103.857 117.114 87.705  1.00 41.04  ? 221  TYR A CG    1 
ATOM   1183  C  CD1   . TYR A 1 203  ? 102.966 116.083 87.962  1.00 41.04  ? 221  TYR A CD1   1 
ATOM   1184  C  CD2   . TYR A 1 203  ? 104.762 116.956 86.669  1.00 41.04  ? 221  TYR A CD2   1 
ATOM   1185  C  CE1   . TYR A 1 203  ? 102.968 114.937 87.204  1.00 41.04  ? 221  TYR A CE1   1 
ATOM   1186  C  CE2   . TYR A 1 203  ? 104.770 115.813 85.907  1.00 41.04  ? 221  TYR A CE2   1 
ATOM   1187  C  CZ    . TYR A 1 203  ? 103.871 114.806 86.178  1.00 41.04  ? 221  TYR A CZ    1 
ATOM   1188  O  OH    . TYR A 1 203  ? 103.871 113.660 85.421  1.00 41.04  ? 221  TYR A OH    1 
ATOM   1189  N  N     . SER A 1 204  ? 102.085 119.810 90.731  1.00 41.17  ? 222  SER A N     1 
ATOM   1190  C  CA    . SER A 1 204  ? 102.120 120.664 91.907  1.00 41.17  ? 222  SER A CA    1 
ATOM   1191  C  C     . SER A 1 204  ? 102.189 119.798 93.155  1.00 41.17  ? 222  SER A C     1 
ATOM   1192  O  O     . SER A 1 204  ? 101.529 118.759 93.239  1.00 41.17  ? 222  SER A O     1 
ATOM   1193  C  CB    . SER A 1 204  ? 100.897 121.583 91.976  1.00 41.17  ? 222  SER A CB    1 
ATOM   1194  O  OG    . SER A 1 204  ? 99.717  120.842 92.231  1.00 41.17  ? 222  SER A OG    1 
ATOM   1195  N  N     . TRP A 1 205  ? 102.997 120.235 94.119  1.00 37.46  ? 223  TRP A N     1 
ATOM   1196  C  CA    . TRP A 1 205  ? 103.121 119.574 95.410  1.00 37.46  ? 223  TRP A CA    1 
ATOM   1197  C  C     . TRP A 1 205  ? 103.159 120.642 96.487  1.00 37.46  ? 223  TRP A C     1 
ATOM   1198  O  O     . TRP A 1 205  ? 103.906 121.616 96.363  1.00 37.46  ? 223  TRP A O     1 
ATOM   1199  C  CB    . TRP A 1 205  ? 104.384 118.712 95.477  1.00 37.46  ? 223  TRP A CB    1 
ATOM   1200  C  CG    . TRP A 1 205  ? 104.701 118.192 96.844  1.00 37.46  ? 223  TRP A CG    1 
ATOM   1201  C  CD1   . TRP A 1 205  ? 104.309 117.001 97.377  1.00 37.46  ? 223  TRP A CD1   1 
ATOM   1202  C  CD2   . TRP A 1 205  ? 105.493 118.839 97.847  1.00 37.46  ? 223  TRP A CD2   1 
ATOM   1203  N  NE1   . TRP A 1 205  ? 104.801 116.868 98.652  1.00 37.46  ? 223  TRP A NE1   1 
ATOM   1204  C  CE2   . TRP A 1 205  ? 105.531 117.983 98.964  1.00 37.46  ? 223  TRP A CE2   1 
ATOM   1205  C  CE3   . TRP A 1 205  ? 106.169 120.060 97.909  1.00 37.46  ? 223  TRP A CE3   1 
ATOM   1206  C  CZ2   . TRP A 1 205  ? 106.217 118.309 100.129 1.00 37.46  ? 223  TRP A CZ2   1 
ATOM   1207  C  CZ3   . TRP A 1 205  ? 106.849 120.382 99.066  1.00 37.46  ? 223  TRP A CZ3   1 
ATOM   1208  C  CH2   . TRP A 1 205  ? 106.869 119.511 100.160 1.00 37.46  ? 223  TRP A CH2   1 
ATOM   1209  N  N     . CYS A 1 206  ? 102.362 120.458 97.535  1.00 42.28  ? 224  CYS A N     1 
ATOM   1210  C  CA    . CYS A 1 206  ? 102.299 121.399 98.643  1.00 42.28  ? 224  CYS A CA    1 
ATOM   1211  C  C     . CYS A 1 206  ? 102.498 120.652 99.952  1.00 42.28  ? 224  CYS A C     1 
ATOM   1212  O  O     . CYS A 1 206  ? 101.937 119.571 100.152 1.00 42.28  ? 224  CYS A O     1 
ATOM   1213  C  CB    . CYS A 1 206  ? 100.966 122.155 98.654  1.00 42.28  ? 224  CYS A CB    1 
ATOM   1214  S  SG    . CYS A 1 206  ? 99.528  121.144 98.246  1.00 42.28  ? 224  CYS A SG    1 
ATOM   1215  N  N     . SER A 1 207  ? 103.293 121.241 100.840 1.00 44.39  ? 225  SER A N     1 
ATOM   1216  C  CA    . SER A 1 207  ? 103.682 120.575 102.073 1.00 44.39  ? 225  SER A CA    1 
ATOM   1217  C  C     . SER A 1 207  ? 102.515 120.496 103.053 1.00 44.39  ? 225  SER A C     1 
ATOM   1218  O  O     . SER A 1 207  ? 101.513 121.207 102.935 1.00 44.39  ? 225  SER A O     1 
ATOM   1219  C  CB    . SER A 1 207  ? 104.853 121.304 102.726 1.00 44.39  ? 225  SER A CB    1 
ATOM   1220  O  OG    . SER A 1 207  ? 104.562 122.678 102.910 1.00 44.39  ? 225  SER A OG    1 
ATOM   1221  N  N     . GLN A 1 208  ? 102.661 119.605 104.037 1.00 53.12  ? 226  GLN A N     1 
ATOM   1222  C  CA    . GLN A 1 208  ? 101.668 119.498 105.099 1.00 53.12  ? 226  GLN A CA    1 
ATOM   1223  C  C     . GLN A 1 208  ? 101.671 120.710 106.018 1.00 53.12  ? 226  GLN A C     1 
ATOM   1224  O  O     . GLN A 1 208  ? 100.718 120.893 106.781 1.00 53.12  ? 226  GLN A O     1 
ATOM   1225  C  CB    . GLN A 1 208  ? 101.898 118.230 105.922 1.00 53.12  ? 226  GLN A CB    1 
ATOM   1226  C  CG    . GLN A 1 208  ? 101.627 116.942 105.169 1.00 53.12  ? 226  GLN A CG    1 
ATOM   1227  C  CD    . GLN A 1 208  ? 101.565 115.737 106.086 1.00 53.12  ? 226  GLN A CD    1 
ATOM   1228  O  OE1   . GLN A 1 208  ? 101.309 115.867 107.283 1.00 53.12  ? 226  GLN A OE1   1 
ATOM   1229  N  NE2   . GLN A 1 208  ? 101.800 114.556 105.528 1.00 53.12  ? 226  GLN A NE2   1 
ATOM   1230  N  N     . ARG A 1 209  ? 102.717 121.537 105.970 1.00 55.57  ? 227  ARG A N     1 
ATOM   1231  C  CA    . ARG A 1 209  ? 102.744 122.753 106.770 1.00 55.57  ? 227  ARG A CA    1 
ATOM   1232  C  C     . ARG A 1 209  ? 101.703 123.773 106.329 1.00 55.57  ? 227  ARG A C     1 
ATOM   1233  O  O     . ARG A 1 209  ? 101.439 124.722 107.076 1.00 55.57  ? 227  ARG A O     1 
ATOM   1234  C  CB    . ARG A 1 209  ? 104.137 123.382 106.730 1.00 55.57  ? 227  ARG A CB    1 
ATOM   1235  C  CG    . ARG A 1 209  ? 105.196 122.564 107.447 1.00 55.57  ? 227  ARG A CG    1 
ATOM   1236  C  CD    . ARG A 1 209  ? 106.424 123.398 107.768 1.00 55.57  ? 227  ARG A CD    1 
ATOM   1237  N  NE    . ARG A 1 209  ? 107.386 122.655 108.574 1.00 55.57  ? 227  ARG A NE    1 
ATOM   1238  C  CZ    . ARG A 1 209  ? 108.471 123.182 109.123 1.00 55.57  ? 227  ARG A CZ    1 
ATOM   1239  N  NH1   . ARG A 1 209  ? 108.764 124.464 108.983 1.00 55.57  ? 227  ARG A NH1   1 
ATOM   1240  N  NH2   . ARG A 1 209  ? 109.282 122.404 109.833 1.00 55.57  ? 227  ARG A NH2   1 
ATOM   1241  N  N     . LEU A 1 210  ? 101.112 123.608 105.147 1.00 52.37  ? 228  LEU A N     1 
ATOM   1242  C  CA    . LEU A 1 210  ? 100.060 124.492 104.664 1.00 52.37  ? 228  LEU A CA    1 
ATOM   1243  C  C     . LEU A 1 210  ? 98.679  123.862 104.749 1.00 52.37  ? 228  LEU A C     1 
ATOM   1244  O  O     . LEU A 1 210  ? 97.729  124.515 105.192 1.00 52.37  ? 228  LEU A O     1 
ATOM   1245  C  CB    . LEU A 1 210  ? 100.342 124.923 103.218 1.00 52.37  ? 228  LEU A CB    1 
ATOM   1246  C  CG    . LEU A 1 210  ? 101.544 125.843 103.000 1.00 52.37  ? 228  LEU A CG    1 
ATOM   1247  C  CD1   . LEU A 1 210  ? 101.341 126.690 101.754 1.00 52.37  ? 228  LEU A CD1   1 
ATOM   1248  C  CD2   . LEU A 1 210  ? 101.799 126.719 104.219 1.00 52.37  ? 228  LEU A CD2   1 
ATOM   1249  N  N     . VAL A 1 211  ? 98.540  122.602 104.330 1.00 65.19  ? 229  VAL A N     1 
ATOM   1250  C  CA    . VAL A 1 211  ? 97.234  121.949 104.365 1.00 65.19  ? 229  VAL A CA    1 
ATOM   1251  C  C     . VAL A 1 211  ? 96.725  121.831 105.797 1.00 65.19  ? 229  VAL A C     1 
ATOM   1252  O  O     . VAL A 1 211  ? 95.511  121.801 106.032 1.00 65.19  ? 229  VAL A O     1 
ATOM   1253  C  CB    . VAL A 1 211  ? 97.303  120.577 103.662 1.00 65.19  ? 229  VAL A CB    1 
ATOM   1254  C  CG1   . VAL A 1 211  ? 98.116  119.588 104.478 1.00 65.19  ? 229  VAL A CG1   1 
ATOM   1255  C  CG2   . VAL A 1 211  ? 95.903  120.040 103.393 1.00 65.19  ? 229  VAL A CG2   1 
ATOM   1256  N  N     . GLU A 1 212  ? 97.629  121.774 106.771 1.00 68.04  ? 230  GLU A N     1 
ATOM   1257  C  CA    . GLU A 1 212  ? 97.269  121.765 108.181 1.00 68.04  ? 230  GLU A CA    1 
ATOM   1258  C  C     . GLU A 1 212  ? 97.909  122.965 108.865 1.00 68.04  ? 230  GLU A C     1 
ATOM   1259  O  O     . GLU A 1 212  ? 99.062  123.308 108.587 1.00 68.04  ? 230  GLU A O     1 
ATOM   1260  C  CB    . GLU A 1 212  ? 97.698  120.460 108.857 1.00 68.04  ? 230  GLU A CB    1 
ATOM   1261  C  CG    . GLU A 1 212  ? 97.120  119.221 108.188 1.00 68.04  ? 230  GLU A CG    1 
ATOM   1262  C  CD    . GLU A 1 212  ? 97.127  118.005 109.091 1.00 68.04  ? 230  GLU A CD    1 
ATOM   1263  O  OE1   . GLU A 1 212  ? 97.468  118.148 110.284 1.00 68.04  ? 230  GLU A OE1   1 
ATOM   1264  O  OE2   . GLU A 1 212  ? 96.787  116.904 108.608 1.00 68.04  ? 230  GLU A OE2   1 
ATOM   1265  N  N     . GLU A 1 213  ? 97.153  123.600 109.757 1.00 74.75  ? 231  GLU A N     1 
ATOM   1266  C  CA    . GLU A 1 213  ? 97.502  124.908 110.294 1.00 74.75  ? 231  GLU A CA    1 
ATOM   1267  C  C     . GLU A 1 213  ? 98.134  124.848 111.681 1.00 74.75  ? 231  GLU A C     1 
ATOM   1268  O  O     . GLU A 1 213  ? 98.317  125.897 112.307 1.00 74.75  ? 231  GLU A O     1 
ATOM   1269  C  CB    . GLU A 1 213  ? 96.263  125.807 110.325 1.00 74.75  ? 231  GLU A CB    1 
ATOM   1270  C  CG    . GLU A 1 213  ? 95.070  125.228 111.081 1.00 74.75  ? 231  GLU A CG    1 
ATOM   1271  C  CD    . GLU A 1 213  ? 94.224  124.286 110.237 1.00 74.75  ? 231  GLU A CD    1 
ATOM   1272  O  OE1   . GLU A 1 213  ? 94.727  123.775 109.214 1.00 74.75  ? 231  GLU A OE1   1 
ATOM   1273  O  OE2   . GLU A 1 213  ? 93.050  124.060 110.597 1.00 74.75  ? 231  GLU A OE2   1 
ATOM   1274  N  N     . ARG A 1 214  ? 98.469  123.661 112.177 1.00 76.83  ? 232  ARG A N     1 
ATOM   1275  C  CA    . ARG A 1 214  ? 99.114  123.565 113.478 1.00 76.83  ? 232  ARG A CA    1 
ATOM   1276  C  C     . ARG A 1 214  ? 100.526 124.138 113.415 1.00 76.83  ? 232  ARG A C     1 
ATOM   1277  O  O     . ARG A 1 214  ? 101.166 124.162 112.360 1.00 76.83  ? 232  ARG A O     1 
ATOM   1278  C  CB    . ARG A 1 214  ? 99.150  122.114 113.958 1.00 76.83  ? 232  ARG A CB    1 
ATOM   1279  C  CG    . ARG A 1 214  ? 100.218 121.259 113.303 1.00 76.83  ? 232  ARG A CG    1 
ATOM   1280  C  CD    . ARG A 1 214  ? 99.965  119.776 113.528 1.00 76.83  ? 232  ARG A CD    1 
ATOM   1281  N  NE    . ARG A 1 214  ? 98.821  119.296 112.762 1.00 76.83  ? 232  ARG A NE    1 
ATOM   1282  C  CZ    . ARG A 1 214  ? 97.598  119.142 113.252 1.00 76.83  ? 232  ARG A CZ    1 
ATOM   1283  N  NH1   . ARG A 1 214  ? 97.322  119.404 114.519 1.00 76.83  ? 232  ARG A NH1   1 
ATOM   1284  N  NH2   . ARG A 1 214  ? 96.627  118.715 112.449 1.00 76.83  ? 232  ARG A NH2   1 
ATOM   1285  N  N     . TYR A 1 215  ? 101.006 124.618 114.561 1.00 81.80  ? 233  TYR A N     1 
ATOM   1286  C  CA    . TYR A 1 215  ? 102.296 125.291 114.649 1.00 81.80  ? 233  TYR A CA    1 
ATOM   1287  C  C     . TYR A 1 215  ? 103.367 124.439 115.318 1.00 81.80  ? 233  TYR A C     1 
ATOM   1288  O  O     . TYR A 1 215  ? 104.438 124.958 115.649 1.00 81.80  ? 233  TYR A O     1 
ATOM   1289  C  CB    . TYR A 1 215  ? 102.145 126.619 115.394 1.00 81.80  ? 233  TYR A CB    1 
ATOM   1290  C  CG    . TYR A 1 215  ? 101.387 126.505 116.698 1.00 81.80  ? 233  TYR A CG    1 
ATOM   1291  C  CD1   . TYR A 1 215  ? 102.030 126.119 117.868 1.00 81.80  ? 233  TYR A CD1   1 
ATOM   1292  C  CD2   . TYR A 1 215  ? 100.029 126.786 116.760 1.00 81.80  ? 233  TYR A CD2   1 
ATOM   1293  C  CE1   . TYR A 1 215  ? 101.340 126.013 119.060 1.00 81.80  ? 233  TYR A CE1   1 
ATOM   1294  C  CE2   . TYR A 1 215  ? 99.331  126.683 117.948 1.00 81.80  ? 233  TYR A CE2   1 
ATOM   1295  C  CZ    . TYR A 1 215  ? 99.992  126.297 119.095 1.00 81.80  ? 233  TYR A CZ    1 
ATOM   1296  O  OH    . TYR A 1 215  ? 99.302  126.194 120.281 1.00 81.80  ? 233  TYR A OH    1 
ATOM   1297  N  N     . SER A 1 216  ? 103.110 123.148 115.525 1.00 78.58  ? 234  SER A N     1 
ATOM   1298  C  CA    . SER A 1 216  ? 104.071 122.267 116.189 1.00 78.58  ? 234  SER A CA    1 
ATOM   1299  C  C     . SER A 1 216  ? 105.088 121.759 115.165 1.00 78.58  ? 234  SER A C     1 
ATOM   1300  O  O     . SER A 1 216  ? 105.170 120.572 114.842 1.00 78.58  ? 234  SER A O     1 
ATOM   1301  C  CB    . SER A 1 216  ? 103.351 121.119 116.883 1.00 78.58  ? 234  SER A CB    1 
ATOM   1302  O  OG    . SER A 1 216  ? 104.270 120.264 117.540 1.00 78.58  ? 234  SER A OG    1 
ATOM   1303  N  N     . TRP A 1 217  ? 105.881 122.696 114.653 1.00 70.97  ? 235  TRP A N     1 
ATOM   1304  C  CA    . TRP A 1 217  ? 106.930 122.398 113.686 1.00 70.97  ? 235  TRP A CA    1 
ATOM   1305  C  C     . TRP A 1 217  ? 108.284 122.640 114.337 1.00 70.97  ? 235  TRP A C     1 
ATOM   1306  O  O     . TRP A 1 217  ? 108.557 123.744 114.820 1.00 70.97  ? 235  TRP A O     1 
ATOM   1307  C  CB    . TRP A 1 217  ? 106.779 123.250 112.425 1.00 70.97  ? 235  TRP A CB    1 
ATOM   1308  C  CG    . TRP A 1 217  ? 105.396 123.244 111.839 1.00 70.97  ? 235  TRP A CG    1 
ATOM   1309  C  CD1   . TRP A 1 217  ? 104.647 124.335 111.509 1.00 70.97  ? 235  TRP A CD1   1 
ATOM   1310  C  CD2   . TRP A 1 217  ? 104.595 122.097 111.520 1.00 70.97  ? 235  TRP A CD2   1 
ATOM   1311  N  NE1   . TRP A 1 217  ? 103.434 123.941 111.000 1.00 70.97  ? 235  TRP A NE1   1 
ATOM   1312  C  CE2   . TRP A 1 217  ? 103.377 122.572 110.996 1.00 70.97  ? 235  TRP A CE2   1 
ATOM   1313  C  CE3   . TRP A 1 217  ? 104.790 120.716 111.622 1.00 70.97  ? 235  TRP A CE3   1 
ATOM   1314  C  CZ2   . TRP A 1 217  ? 102.360 121.718 110.579 1.00 70.97  ? 235  TRP A CZ2   1 
ATOM   1315  C  CZ3   . TRP A 1 217  ? 103.779 119.870 111.209 1.00 70.97  ? 235  TRP A CZ3   1 
ATOM   1316  C  CH2   . TRP A 1 217  ? 102.580 120.374 110.693 1.00 70.97  ? 235  TRP A CH2   1 
ATOM   1317  N  N     . THR A 1 218  ? 109.124 121.611 114.346 1.00 64.14  ? 236  THR A N     1 
ATOM   1318  C  CA    . THR A 1 218  ? 110.442 121.684 114.953 1.00 64.14  ? 236  THR A CA    1 
ATOM   1319  C  C     . THR A 1 218  ? 111.468 122.221 113.961 1.00 64.14  ? 236  THR A C     1 
ATOM   1320  O  O     . THR A 1 218  ? 111.242 122.254 112.749 1.00 64.14  ? 236  THR A O     1 
ATOM   1321  C  CB    . THR A 1 218  ? 110.879 120.308 115.456 1.00 64.14  ? 236  THR A CB    1 
ATOM   1322  O  OG1   . THR A 1 218  ? 110.812 119.362 114.381 1.00 64.14  ? 236  THR A OG1   1 
ATOM   1323  C  CG2   . THR A 1 218  ? 109.978 119.843 116.589 1.00 64.14  ? 236  THR A CG2   1 
ATOM   1324  N  N     . SER A 1 219  ? 112.609 122.651 114.498 1.00 57.99  ? 237  SER A N     1 
ATOM   1325  C  CA    . SER A 1 219  ? 113.738 123.039 113.663 1.00 57.99  ? 237  SER A CA    1 
ATOM   1326  C  C     . SER A 1 219  ? 114.533 121.840 113.166 1.00 57.99  ? 237  SER A C     1 
ATOM   1327  O  O     . SER A 1 219  ? 115.356 121.996 112.257 1.00 57.99  ? 237  SER A O     1 
ATOM   1328  C  CB    . SER A 1 219  ? 114.664 123.986 114.431 1.00 57.99  ? 237  SER A CB    1 
ATOM   1329  O  OG    . SER A 1 219  ? 113.993 125.183 114.781 1.00 57.99  ? 237  SER A OG    1 
ATOM   1330  N  N     . GLN A 1 220  ? 114.313 120.662 113.742 1.00 43.13  ? 238  GLN A N     1 
ATOM   1331  C  CA    . GLN A 1 220  ? 114.937 119.446 113.243 1.00 43.13  ? 238  GLN A CA    1 
ATOM   1332  C  C     . GLN A 1 220  ? 114.360 119.095 111.878 1.00 43.13  ? 238  GLN A C     1 
ATOM   1333  O  O     . GLN A 1 220  ? 113.140 119.094 111.690 1.00 43.13  ? 238  GLN A O     1 
ATOM   1334  C  CB    . GLN A 1 220  ? 114.720 118.301 114.232 1.00 43.13  ? 238  GLN A CB    1 
ATOM   1335  C  CG    . GLN A 1 220  ? 115.291 116.963 113.797 1.00 43.13  ? 238  GLN A CG    1 
ATOM   1336  C  CD    . GLN A 1 220  ? 114.230 116.020 113.264 1.00 43.13  ? 238  GLN A CD    1 
ATOM   1337  O  OE1   . GLN A 1 220  ? 113.141 116.445 112.881 1.00 43.13  ? 238  GLN A OE1   1 
ATOM   1338  N  NE2   . GLN A 1 220  ? 114.543 114.730 113.243 1.00 43.13  ? 238  GLN A NE2   1 
ATOM   1339  N  N     . LEU A 1 221  ? 115.237 118.801 110.924 1.00 31.71  ? 239  LEU A N     1 
ATOM   1340  C  CA    . LEU A 1 221  ? 114.843 118.525 109.550 1.00 31.71  ? 239  LEU A CA    1 
ATOM   1341  C  C     . LEU A 1 221  ? 115.089 117.060 109.226 1.00 31.71  ? 239  LEU A C     1 
ATOM   1342  O  O     . LEU A 1 221  ? 116.184 116.540 109.460 1.00 31.71  ? 239  LEU A O     1 
ATOM   1343  C  CB    . LEU A 1 221  ? 115.598 119.426 108.571 1.00 31.71  ? 239  LEU A CB    1 
ATOM   1344  C  CG    . LEU A 1 221  ? 114.926 120.762 108.254 1.00 31.71  ? 239  LEU A CG    1 
ATOM   1345  C  CD1   . LEU A 1 221  ? 115.918 121.734 107.650 1.00 31.71  ? 239  LEU A CD1   1 
ATOM   1346  C  CD2   . LEU A 1 221  ? 113.749 120.545 107.317 1.00 31.71  ? 239  LEU A CD2   1 
ATOM   1347  N  N     . SER A 1 222  ? 114.066 116.406 108.689 1.00 34.19  ? 240  SER A N     1 
ATOM   1348  C  CA    . SER A 1 222  ? 114.076 115.009 108.295 1.00 34.19  ? 240  SER A CA    1 
ATOM   1349  C  C     . SER A 1 222  ? 113.581 114.911 106.861 1.00 34.19  ? 240  SER A C     1 
ATOM   1350  O  O     . SER A 1 222  ? 112.803 115.762 106.417 1.00 34.19  ? 240  SER A O     1 
ATOM   1351  C  CB    . SER A 1 222  ? 113.177 114.179 109.226 1.00 34.19  ? 240  SER A CB    1 
ATOM   1352  O  OG    . SER A 1 222  ? 113.409 112.789 109.095 1.00 34.19  ? 240  SER A OG    1 
ATOM   1353  N  N     . PRO A 1 223  ? 114.017 113.898 106.104 1.00 34.86  ? 241  PRO A N     1 
ATOM   1354  C  CA    . PRO A 1 223  ? 113.617 113.829 104.688 1.00 34.86  ? 241  PRO A CA    1 
ATOM   1355  C  C     . PRO A 1 223  ? 112.122 113.672 104.480 1.00 34.86  ? 241  PRO A C     1 
ATOM   1356  O  O     . PRO A 1 223  ? 111.639 113.929 103.370 1.00 34.86  ? 241  PRO A O     1 
ATOM   1357  C  CB    . PRO A 1 223  ? 114.389 112.611 104.163 1.00 34.86  ? 241  PRO A CB    1 
ATOM   1358  C  CG    . PRO A 1 223  ? 114.664 111.789 105.369 1.00 34.86  ? 241  PRO A CG    1 
ATOM   1359  C  CD    . PRO A 1 223  ? 114.897 112.775 106.472 1.00 34.86  ? 241  PRO A CD    1 
ATOM   1360  N  N     . ALA A 1 224  ? 111.370 113.266 105.506 1.00 35.35  ? 242  ALA A N     1 
ATOM   1361  C  CA    . ALA A 1 224  ? 109.924 113.130 105.382 1.00 35.35  ? 242  ALA A CA    1 
ATOM   1362  C  C     . ALA A 1 224  ? 109.211 114.470 105.269 1.00 35.35  ? 242  ALA A C     1 
ATOM   1363  O  O     . ALA A 1 224  ? 107.986 114.486 105.113 1.00 35.35  ? 242  ALA A O     1 
ATOM   1364  C  CB    . ALA A 1 224  ? 109.364 112.347 106.569 1.00 35.35  ? 242  ALA A CB    1 
ATOM   1365  N  N     . ASP A 1 225  ? 109.936 115.583 105.350 1.00 40.26  ? 243  ASP A N     1 
ATOM   1366  C  CA    . ASP A 1 225  ? 109.364 116.912 105.197 1.00 40.26  ? 243  ASP A CA    1 
ATOM   1367  C  C     . ASP A 1 225  ? 109.636 117.517 103.825 1.00 40.26  ? 243  ASP A C     1 
ATOM   1368  O  O     . ASP A 1 225  ? 109.365 118.704 103.621 1.00 40.26  ? 243  ASP A O     1 
ATOM   1369  C  CB    . ASP A 1 225  ? 109.900 117.844 106.285 1.00 40.26  ? 243  ASP A CB    1 
ATOM   1370  C  CG    . ASP A 1 225  ? 109.666 117.305 107.683 1.00 40.26  ? 243  ASP A CG    1 
ATOM   1371  O  OD1   . ASP A 1 225  ? 108.634 116.637 107.899 1.00 40.26  ? 243  ASP A OD1   1 
ATOM   1372  O  OD2   . ASP A 1 225  ? 110.517 117.547 108.565 1.00 40.26  ? 243  ASP A OD2   1 
ATOM   1373  N  N     . LEU A 1 226  ? 110.163 116.740 102.886 1.00 30.37  ? 244  LEU A N     1 
ATOM   1374  C  CA    . LEU A 1 226  ? 110.661 117.268 101.624 1.00 30.37  ? 244  LEU A CA    1 
ATOM   1375  C  C     . LEU A 1 226  ? 109.892 116.663 100.448 1.00 30.37  ? 244  LEU A C     1 
ATOM   1376  O  O     . LEU A 1 226  ? 108.918 115.927 100.625 1.00 30.37  ? 244  LEU A O     1 
ATOM   1377  C  CB    . LEU A 1 226  ? 112.165 117.013 101.510 1.00 30.37  ? 244  LEU A CB    1 
ATOM   1378  C  CG    . LEU A 1 226  ? 113.001 117.662 102.607 1.00 30.37  ? 244  LEU A CG    1 
ATOM   1379  C  CD1   . LEU A 1 226  ? 114.464 117.291 102.469 1.00 30.37  ? 244  LEU A CD1   1 
ATOM   1380  C  CD2   . LEU A 1 226  ? 112.815 119.157 102.542 1.00 30.37  ? 244  LEU A CD2   1 
ATOM   1381  N  N     . ILE A 1 227  ? 110.352 116.976 99.241  1.00 27.60  ? 245  ILE A N     1 
ATOM   1382  C  CA    . ILE A 1 227  ? 109.636 116.648 98.012  1.00 27.60  ? 245  ILE A CA    1 
ATOM   1383  C  C     . ILE A 1 227  ? 110.113 115.282 97.529  1.00 27.60  ? 245  ILE A C     1 
ATOM   1384  O  O     . ILE A 1 227  ? 111.295 115.143 97.179  1.00 27.60  ? 245  ILE A O     1 
ATOM   1385  C  CB    . ILE A 1 227  ? 109.870 117.711 96.935  1.00 27.60  ? 245  ILE A CB    1 
ATOM   1386  C  CG1   . ILE A 1 227  ? 109.754 119.111 97.535  1.00 27.60  ? 245  ILE A CG1   1 
ATOM   1387  C  CG2   . ILE A 1 227  ? 108.891 117.533 95.789  1.00 27.60  ? 245  ILE A CG2   1 
ATOM   1388  C  CD1   . ILE A 1 227  ? 110.044 120.207 96.555  1.00 27.60  ? 245  ILE A CD1   1 
ATOM   1389  N  N     . PRO A 1 228  ? 109.250 114.266 97.487  1.00 30.16  ? 246  PRO A N     1 
ATOM   1390  C  CA    . PRO A 1 228  ? 109.649 112.968 96.923  1.00 30.16  ? 246  PRO A CA    1 
ATOM   1391  C  C     . PRO A 1 228  ? 109.480 112.955 95.410  1.00 30.16  ? 246  PRO A C     1 
ATOM   1392  O  O     . PRO A 1 228  ? 108.375 113.132 94.894  1.00 30.16  ? 246  PRO A O     1 
ATOM   1393  C  CB    . PRO A 1 228  ? 108.696 111.980 97.607  1.00 30.16  ? 246  PRO A CB    1 
ATOM   1394  C  CG    . PRO A 1 228  ? 107.482 112.783 97.886  1.00 30.16  ? 246  PRO A CG    1 
ATOM   1395  C  CD    . PRO A 1 228  ? 107.935 114.201 98.143  1.00 30.16  ? 246  PRO A CD    1 
ATOM   1396  N  N     . LEU A 1 229  ? 110.585 112.746 94.697  1.00 34.85  ? 247  LEU A N     1 
ATOM   1397  C  CA    . LEU A 1 229  ? 110.574 112.672 93.241  1.00 34.85  ? 247  LEU A CA    1 
ATOM   1398  C  C     . LEU A 1 229  ? 110.927 111.289 92.721  1.00 34.85  ? 247  LEU A C     1 
ATOM   1399  O  O     . LEU A 1 229  ? 110.180 110.729 91.910  1.00 34.85  ? 247  LEU A O     1 
ATOM   1400  C  CB    . LEU A 1 229  ? 111.543 113.705 92.642  1.00 34.85  ? 247  LEU A CB    1 
ATOM   1401  C  CG    . LEU A 1 229  ? 111.131 115.176 92.665  1.00 34.85  ? 247  LEU A CG    1 
ATOM   1402  C  CD1   . LEU A 1 229  ? 112.116 116.015 91.871  1.00 34.85  ? 247  LEU A CD1   1 
ATOM   1403  C  CD2   . LEU A 1 229  ? 109.733 115.343 92.114  1.00 34.85  ? 247  LEU A CD2   1 
ATOM   1404  N  N     . GLU A 1 230  ? 112.046 110.720 93.166  1.00 44.32  ? 248  GLU A N     1 
ATOM   1405  C  CA    . GLU A 1 230  ? 112.561 109.491 92.580  1.00 44.32  ? 248  GLU A CA    1 
ATOM   1406  C  C     . GLU A 1 230  ? 111.632 108.312 92.844  1.00 44.32  ? 248  GLU A C     1 
ATOM   1407  O  O     . GLU A 1 230  ? 110.912 108.264 93.845  1.00 44.32  ? 248  GLU A O     1 
ATOM   1408  C  CB    . GLU A 1 230  ? 113.953 109.182 93.127  1.00 44.32  ? 248  GLU A CB    1 
ATOM   1409  C  CG    . GLU A 1 230  ? 114.930 110.333 93.013  1.00 44.32  ? 248  GLU A CG    1 
ATOM   1410  C  CD    . GLU A 1 230  ? 116.365 109.884 93.168  1.00 44.32  ? 248  GLU A CD    1 
ATOM   1411  O  OE1   . GLU A 1 230  ? 116.614 108.663 93.098  1.00 44.32  ? 248  GLU A OE1   1 
ATOM   1412  O  OE2   . GLU A 1 230  ? 117.245 110.749 93.360  1.00 44.32  ? 248  GLU A OE2   1 
ATOM   1413  N  N     . VAL A 1 231  ? 111.659 107.352 91.925  1.00 52.79  ? 249  VAL A N     1 
ATOM   1414  C  CA    . VAL A 1 231  ? 110.844 106.144 92.023  1.00 52.79  ? 249  VAL A CA    1 
ATOM   1415  C  C     . VAL A 1 231  ? 111.540 105.146 92.941  1.00 52.79  ? 249  VAL A C     1 
ATOM   1416  O  O     . VAL A 1 231  ? 112.777 105.141 93.024  1.00 52.79  ? 249  VAL A O     1 
ATOM   1417  C  CB    . VAL A 1 231  ? 110.584 105.537 90.636  1.00 52.79  ? 249  VAL A CB    1 
ATOM   1418  C  CG1   . VAL A 1 231  ? 109.804 106.512 89.771  1.00 52.79  ? 249  VAL A CG1   1 
ATOM   1419  C  CG2   . VAL A 1 231  ? 111.897 105.160 89.967  1.00 52.79  ? 249  VAL A CG2   1 
ATOM   1420  N  N     . PRO A 1 232  ? 110.795 104.292 93.656  1.00 56.17  ? 250  PRO A N     1 
ATOM   1421  C  CA    . PRO A 1 232  ? 111.395 103.252 94.495  1.00 56.17  ? 250  PRO A CA    1 
ATOM   1422  C  C     . PRO A 1 232  ? 111.777 102.009 93.697  1.00 56.17  ? 250  PRO A C     1 
ATOM   1423  O  O     . PRO A 1 232  ? 111.134 101.728 92.686  1.00 56.17  ? 250  PRO A O     1 
ATOM   1424  C  CB    . PRO A 1 232  ? 110.287 102.937 95.498  1.00 56.17  ? 250  PRO A CB    1 
ATOM   1425  C  CG    . PRO A 1 232  ? 109.033 103.204 94.743  1.00 56.17  ? 250  PRO A CG    1 
ATOM   1426  C  CD    . PRO A 1 232  ? 109.333 104.362 93.827  1.00 56.17  ? 250  PRO A CD    1 
ATOM   1427  N  N     . GLN A 1 244  ? 114.952 104.026 84.697  1.00 52.52  ? 262  GLN A N     1 
ATOM   1428  C  CA    . GLN A 1 244  ? 115.662 104.247 85.951  1.00 52.52  ? 262  GLN A CA    1 
ATOM   1429  C  C     . GLN A 1 244  ? 116.305 105.627 85.977  1.00 52.52  ? 262  GLN A C     1 
ATOM   1430  O  O     . GLN A 1 244  ? 116.120 106.390 86.924  1.00 52.52  ? 262  GLN A O     1 
ATOM   1431  C  CB    . GLN A 1 244  ? 116.723 103.166 86.169  1.00 52.52  ? 262  GLN A CB    1 
ATOM   1432  C  CG    . GLN A 1 244  ? 116.167 101.805 86.574  1.00 52.52  ? 262  GLN A CG    1 
ATOM   1433  C  CD    . GLN A 1 244  ? 115.517 101.058 85.423  1.00 52.52  ? 262  GLN A CD    1 
ATOM   1434  O  OE1   . GLN A 1 244  ? 115.523 101.521 84.282  1.00 52.52  ? 262  GLN A OE1   1 
ATOM   1435  N  NE2   . GLN A 1 244  ? 114.955 99.892  85.718  1.00 52.52  ? 262  GLN A NE2   1 
ATOM   1436  N  N     . GLU A 1 245  ? 117.068 105.937 84.933  1.00 47.27  ? 263  GLU A N     1 
ATOM   1437  C  CA    . GLU A 1 245  ? 117.701 107.244 84.831  1.00 47.27  ? 263  GLU A CA    1 
ATOM   1438  C  C     . GLU A 1 245  ? 116.650 108.336 84.684  1.00 47.27  ? 263  GLU A C     1 
ATOM   1439  O  O     . GLU A 1 245  ? 115.657 108.175 83.970  1.00 47.27  ? 263  GLU A O     1 
ATOM   1440  C  CB    . GLU A 1 245  ? 118.663 107.280 83.643  1.00 47.27  ? 263  GLU A CB    1 
ATOM   1441  C  CG    . GLU A 1 245  ? 119.957 106.512 83.850  1.00 47.27  ? 263  GLU A CG    1 
ATOM   1442  C  CD    . GLU A 1 245  ? 119.794 105.021 83.641  1.00 47.27  ? 263  GLU A CD    1 
ATOM   1443  O  OE1   . GLU A 1 245  ? 118.708 104.595 83.195  1.00 47.27  ? 263  GLU A OE1   1 
ATOM   1444  O  OE2   . GLU A 1 245  ? 120.754 104.274 83.923  1.00 47.27  ? 263  GLU A OE2   1 
ATOM   1445  N  N     . GLN A 1 246  ? 116.873 109.457 85.368  1.00 36.99  ? 264  GLN A N     1 
ATOM   1446  C  CA    . GLN A 1 246  ? 115.942 110.573 85.344  1.00 36.99  ? 264  GLN A CA    1 
ATOM   1447  C  C     . GLN A 1 246  ? 116.709 111.881 85.245  1.00 36.99  ? 264  GLN A C     1 
ATOM   1448  O  O     . GLN A 1 246  ? 117.840 111.994 85.719  1.00 36.99  ? 264  GLN A O     1 
ATOM   1449  C  CB    . GLN A 1 246  ? 115.055 110.607 86.593  1.00 36.99  ? 264  GLN A CB    1 
ATOM   1450  C  CG    . GLN A 1 246  ? 114.492 109.267 87.007  1.00 36.99  ? 264  GLN A CG    1 
ATOM   1451  C  CD    . GLN A 1 246  ? 113.450 109.401 88.088  1.00 36.99  ? 264  GLN A CD    1 
ATOM   1452  O  OE1   . GLN A 1 246  ? 112.659 110.342 88.083  1.00 36.99  ? 264  GLN A OE1   1 
ATOM   1453  N  NE2   . GLN A 1 246  ? 113.447 108.467 89.030  1.00 36.99  ? 264  GLN A NE2   1 
ATOM   1454  N  N     . LEU A 1 247  ? 116.073 112.873 84.633  1.00 28.74  ? 265  LEU A N     1 
ATOM   1455  C  CA    . LEU A 1 247  ? 116.600 114.227 84.572  1.00 28.74  ? 265  LEU A CA    1 
ATOM   1456  C  C     . LEU A 1 247  ? 115.561 115.182 85.136  1.00 28.74  ? 265  LEU A C     1 
ATOM   1457  O  O     . LEU A 1 247  ? 114.410 115.186 84.691  1.00 28.74  ? 265  LEU A O     1 
ATOM   1458  C  CB    . LEU A 1 247  ? 116.961 114.622 83.140  1.00 28.74  ? 265  LEU A CB    1 
ATOM   1459  C  CG    . LEU A 1 247  ? 117.603 115.996 82.964  1.00 28.74  ? 265  LEU A CG    1 
ATOM   1460  C  CD1   . LEU A 1 247  ? 118.961 116.045 83.634  1.00 28.74  ? 265  LEU A CD1   1 
ATOM   1461  C  CD2   . LEU A 1 247  ? 117.719 116.333 81.494  1.00 28.74  ? 265  LEU A CD2   1 
ATOM   1462  N  N     . VAL A 1 248  ? 115.968 115.985 86.113  1.00 26.02  ? 266  VAL A N     1 
ATOM   1463  C  CA    . VAL A 1 248  ? 115.108 116.982 86.735  1.00 26.02  ? 266  VAL A CA    1 
ATOM   1464  C  C     . VAL A 1 248  ? 115.717 118.345 86.456  1.00 26.02  ? 266  VAL A C     1 
ATOM   1465  O  O     . VAL A 1 248  ? 116.893 118.579 86.763  1.00 26.02  ? 266  VAL A O     1 
ATOM   1466  C  CB    . VAL A 1 248  ? 114.954 116.739 88.241  1.00 26.02  ? 266  VAL A CB    1 
ATOM   1467  C  CG1   . VAL A 1 248  ? 114.254 117.909 88.897  1.00 26.02  ? 266  VAL A CG1   1 
ATOM   1468  C  CG2   . VAL A 1 248  ? 114.192 115.456 88.477  1.00 26.02  ? 266  VAL A CG2   1 
ATOM   1469  N  N     . VAL A 1 249  ? 114.927 119.237 85.870  1.00 24.99  ? 267  VAL A N     1 
ATOM   1470  C  CA    . VAL A 1 249  ? 115.425 120.516 85.393  1.00 24.99  ? 267  VAL A CA    1 
ATOM   1471  C  C     . VAL A 1 249  ? 114.786 121.637 86.201  1.00 24.99  ? 267  VAL A C     1 
ATOM   1472  O  O     . VAL A 1 249  ? 113.728 121.480 86.817  1.00 24.99  ? 267  VAL A O     1 
ATOM   1473  C  CB    . VAL A 1 249  ? 115.156 120.695 83.885  1.00 24.99  ? 267  VAL A CB    1 
ATOM   1474  C  CG1   . VAL A 1 249  ? 116.099 121.728 83.285  1.00 24.99  ? 267  VAL A CG1   1 
ATOM   1475  C  CG2   . VAL A 1 249  ? 115.292 119.366 83.170  1.00 24.99  ? 267  VAL A CG2   1 
ATOM   1476  N  N     . GLY A 1 250  ? 115.449 122.785 86.195  1.00 24.21  ? 268  GLY A N     1 
ATOM   1477  C  CA    . GLY A 1 250  ? 114.938 123.953 86.884  1.00 24.21  ? 268  GLY A CA    1 
ATOM   1478  C  C     . GLY A 1 250  ? 115.904 125.099 86.714  1.00 24.21  ? 268  GLY A C     1 
ATOM   1479  O  O     . GLY A 1 250  ? 116.944 124.976 86.060  1.00 24.21  ? 268  GLY A O     1 
ATOM   1480  N  N     . HIS A 1 251  ? 115.539 126.231 87.301  1.00 31.03  ? 269  HIS A N     1 
ATOM   1481  C  CA    . HIS A 1 251  ? 116.437 127.370 87.404  1.00 31.03  ? 269  HIS A CA    1 
ATOM   1482  C  C     . HIS A 1 251  ? 116.958 127.414 88.832  1.00 31.03  ? 269  HIS A C     1 
ATOM   1483  O  O     . HIS A 1 251  ? 116.165 127.473 89.780  1.00 31.03  ? 269  HIS A O     1 
ATOM   1484  C  CB    . HIS A 1 251  ? 115.735 128.678 87.042  1.00 31.03  ? 269  HIS A CB    1 
ATOM   1485  C  CG    . HIS A 1 251  ? 116.672 129.831 86.869  1.00 31.03  ? 269  HIS A CG    1 
ATOM   1486  N  ND1   . HIS A 1 251  ? 117.176 130.202 85.642  1.00 31.03  ? 269  HIS A ND1   1 
ATOM   1487  C  CD2   . HIS A 1 251  ? 117.208 130.687 87.771  1.00 31.03  ? 269  HIS A CD2   1 
ATOM   1488  C  CE1   . HIS A 1 251  ? 117.976 131.243 85.794  1.00 31.03  ? 269  HIS A CE1   1 
ATOM   1489  N  NE2   . HIS A 1 251  ? 118.012 131.557 87.075  1.00 31.03  ? 269  HIS A NE2   1 
ATOM   1490  N  N     . ASN A 1 252  ? 118.283 127.381 88.980  1.00 33.48  ? 270  ASN A N     1 
ATOM   1491  C  CA    . ASN A 1 252  ? 118.937 127.215 90.275  1.00 33.48  ? 270  ASN A CA    1 
ATOM   1492  C  C     . ASN A 1 252  ? 118.439 125.937 90.957  1.00 33.48  ? 270  ASN A C     1 
ATOM   1493  O  O     . ASN A 1 252  ? 117.836 125.962 92.033  1.00 33.48  ? 270  ASN A O     1 
ATOM   1494  C  CB    . ASN A 1 252  ? 118.724 128.445 91.163  1.00 33.48  ? 270  ASN A CB    1 
ATOM   1495  C  CG    . ASN A 1 252  ? 119.958 128.811 91.953  1.00 33.48  ? 270  ASN A CG    1 
ATOM   1496  O  OD1   . ASN A 1 252  ? 120.786 127.957 92.268  1.00 33.48  ? 270  ASN A OD1   1 
ATOM   1497  N  ND2   . ASN A 1 252  ? 120.090 130.089 92.280  1.00 33.48  ? 270  ASN A ND2   1 
ATOM   1498  N  N     . VAL A 1 253  ? 118.694 124.808 90.290  1.00 25.47  ? 271  VAL A N     1 
ATOM   1499  C  CA    . VAL A 1 253  ? 118.183 123.524 90.761  1.00 25.47  ? 271  VAL A CA    1 
ATOM   1500  C  C     . VAL A 1 253  ? 118.804 123.150 92.093  1.00 25.47  ? 271  VAL A C     1 
ATOM   1501  O  O     . VAL A 1 253  ? 118.214 122.389 92.871  1.00 25.47  ? 271  VAL A O     1 
ATOM   1502  C  CB    . VAL A 1 253  ? 118.430 122.428 89.709  1.00 25.47  ? 271  VAL A CB    1 
ATOM   1503  C  CG1   . VAL A 1 253  ? 117.627 121.187 90.045  1.00 25.47  ? 271  VAL A CG1   1 
ATOM   1504  C  CG2   . VAL A 1 253  ? 118.072 122.935 88.336  1.00 25.47  ? 271  VAL A CG2   1 
ATOM   1505  N  N     . SER A 1 254  ? 120.003 123.662 92.379  1.00 25.16  ? 272  SER A N     1 
ATOM   1506  C  CA    . SER A 1 254  ? 120.638 123.377 93.658  1.00 25.16  ? 272  SER A CA    1 
ATOM   1507  C  C     . SER A 1 254  ? 119.755 123.803 94.822  1.00 25.16  ? 272  SER A C     1 
ATOM   1508  O  O     . SER A 1 254  ? 119.846 123.229 95.913  1.00 25.16  ? 272  SER A O     1 
ATOM   1509  C  CB    . SER A 1 254  ? 121.998 124.067 93.725  1.00 25.16  ? 272  SER A CB    1 
ATOM   1510  O  OG    . SER A 1 254  ? 121.908 125.410 93.288  1.00 25.16  ? 272  SER A OG    1 
ATOM   1511  N  N     . PHE A 1 255  ? 118.894 124.800 94.612  1.00 30.42  ? 273  PHE A N     1 
ATOM   1512  C  CA    . PHE A 1 255  ? 117.875 125.119 95.604  1.00 30.42  ? 273  PHE A CA    1 
ATOM   1513  C  C     . PHE A 1 255  ? 116.794 124.046 95.645  1.00 30.42  ? 273  PHE A C     1 
ATOM   1514  O  O     . PHE A 1 255  ? 116.321 123.678 96.725  1.00 30.42  ? 273  PHE A O     1 
ATOM   1515  C  CB    . PHE A 1 255  ? 117.268 126.488 95.305  1.00 30.42  ? 273  PHE A CB    1 
ATOM   1516  C  CG    . PHE A 1 255  ? 116.131 126.861 96.213  1.00 30.42  ? 273  PHE A CG    1 
ATOM   1517  C  CD1   . PHE A 1 255  ? 116.375 127.433 97.448  1.00 30.42  ? 273  PHE A CD1   1 
ATOM   1518  C  CD2   . PHE A 1 255  ? 114.818 126.649 95.826  1.00 30.42  ? 273  PHE A CD2   1 
ATOM   1519  C  CE1   . PHE A 1 255  ? 115.336 127.783 98.281  1.00 30.42  ? 273  PHE A CE1   1 
ATOM   1520  C  CE2   . PHE A 1 255  ? 113.775 126.994 96.656  1.00 30.42  ? 273  PHE A CE2   1 
ATOM   1521  C  CZ    . PHE A 1 255  ? 114.034 127.561 97.885  1.00 30.42  ? 273  PHE A CZ    1 
ATOM   1522  N  N     . ASP A 1 256  ? 116.381 123.541 94.481  1.00 25.80  ? 274  ASP A N     1 
ATOM   1523  C  CA    . ASP A 1 256  ? 115.361 122.497 94.452  1.00 25.80  ? 274  ASP A CA    1 
ATOM   1524  C  C     . ASP A 1 256  ? 115.894 121.188 95.017  1.00 25.80  ? 274  ASP A C     1 
ATOM   1525  O  O     . ASP A 1 256  ? 115.227 120.537 95.829  1.00 25.80  ? 274  ASP A O     1 
ATOM   1526  C  CB    . ASP A 1 256  ? 114.850 122.284 93.029  1.00 25.80  ? 274  ASP A CB    1 
ATOM   1527  C  CG    . ASP A 1 256  ? 114.187 123.507 92.461  1.00 25.80  ? 274  ASP A CG    1 
ATOM   1528  O  OD1   . ASP A 1 256  ? 114.265 124.578 93.095  1.00 25.80  ? 274  ASP A OD1   1 
ATOM   1529  O  OD2   . ASP A 1 256  ? 113.583 123.396 91.376  1.00 25.80  ? 274  ASP A OD2   1 
ATOM   1530  N  N     . ARG A 1 257  ? 117.095 120.783 94.591  1.00 19.15  ? 275  ARG A N     1 
ATOM   1531  C  CA    . ARG A 1 257  ? 117.647 119.504 95.030  1.00 19.15  ? 275  ARG A CA    1 
ATOM   1532  C  C     . ARG A 1 257  ? 117.773 119.447 96.545  1.00 19.15  ? 275  ARG A C     1 
ATOM   1533  O  O     . ARG A 1 257  ? 117.478 118.416 97.161  1.00 19.15  ? 275  ARG A O     1 
ATOM   1534  C  CB    . ARG A 1 257  ? 119.005 119.259 94.375  1.00 19.15  ? 275  ARG A CB    1 
ATOM   1535  C  CG    . ARG A 1 257  ? 119.708 118.016 94.895  1.00 19.15  ? 275  ARG A CG    1 
ATOM   1536  C  CD    . ARG A 1 257  ? 120.909 117.651 94.051  1.00 19.15  ? 275  ARG A CD    1 
ATOM   1537  N  NE    . ARG A 1 257  ? 121.695 116.587 94.662  1.00 19.15  ? 275  ARG A NE    1 
ATOM   1538  C  CZ    . ARG A 1 257  ? 122.817 116.785 95.338  1.00 19.15  ? 275  ARG A CZ    1 
ATOM   1539  N  NH1   . ARG A 1 257  ? 123.320 117.998 95.501  1.00 19.15  ? 275  ARG A NH1   1 
ATOM   1540  N  NH2   . ARG A 1 257  ? 123.454 115.741 95.858  1.00 19.15  ? 275  ARG A NH2   1 
ATOM   1541  N  N     . ALA A 1 258  ? 118.195 120.551 97.165  1.00 19.45  ? 276  ALA A N     1 
ATOM   1542  C  CA    . ALA A 1 258  ? 118.307 120.591 98.616  1.00 19.45  ? 276  ALA A CA    1 
ATOM   1543  C  C     . ALA A 1 258  ? 116.969 120.366 99.303  1.00 19.45  ? 276  ALA A C     1 
ATOM   1544  O  O     . ALA A 1 258  ? 116.947 120.003 100.482 1.00 19.45  ? 276  ALA A O     1 
ATOM   1545  C  CB    . ALA A 1 258  ? 118.903 121.925 99.063  1.00 19.45  ? 276  ALA A CB    1 
ATOM   1546  N  N     . HIS A 1 259  ? 115.858 120.564 98.596  1.00 22.69  ? 277  HIS A N     1 
ATOM   1547  C  CA    . HIS A 1 259  ? 114.531 120.346 99.151  1.00 22.69  ? 277  HIS A CA    1 
ATOM   1548  C  C     . HIS A 1 259  ? 113.903 119.044 98.675  1.00 22.69  ? 277  HIS A C     1 
ATOM   1549  O  O     . HIS A 1 259  ? 112.701 118.843 98.865  1.00 22.69  ? 277  HIS A O     1 
ATOM   1550  C  CB    . HIS A 1 259  ? 113.619 121.523 98.808  1.00 22.69  ? 277  HIS A CB    1 
ATOM   1551  C  CG    . HIS A 1 259  ? 114.095 122.830 99.357  1.00 22.69  ? 277  HIS A CG    1 
ATOM   1552  N  ND1   . HIS A 1 259  ? 115.041 123.603 98.721  1.00 22.69  ? 277  HIS A ND1   1 
ATOM   1553  C  CD2   . HIS A 1 259  ? 113.762 123.497 100.486 1.00 22.69  ? 277  HIS A CD2   1 
ATOM   1554  C  CE1   . HIS A 1 259  ? 115.268 124.692 99.432  1.00 22.69  ? 277  HIS A CE1   1 
ATOM   1555  N  NE2   . HIS A 1 259  ? 114.504 124.652 100.508 1.00 22.69  ? 277  HIS A NE2   1 
ATOM   1556  N  N     . ILE A 1 260  ? 114.686 118.162 98.062  1.00 22.12  ? 278  ILE A N     1 
ATOM   1557  C  CA    . ILE A 1 260  ? 114.212 116.862 97.599  1.00 22.12  ? 278  ILE A CA    1 
ATOM   1558  C  C     . ILE A 1 260  ? 114.608 115.807 98.619  1.00 22.12  ? 278  ILE A C     1 
ATOM   1559  O  O     . ILE A 1 260  ? 115.678 115.891 99.236  1.00 22.12  ? 278  ILE A O     1 
ATOM   1560  C  CB    . ILE A 1 260  ? 114.771 116.540 96.200  1.00 22.12  ? 278  ILE A CB    1 
ATOM   1561  C  CG1   . ILE A 1 260  ? 114.338 117.619 95.211  1.00 22.12  ? 278  ILE A CG1   1 
ATOM   1562  C  CG2   . ILE A 1 260  ? 114.288 115.184 95.717  1.00 22.12  ? 278  ILE A CG2   1 
ATOM   1563  C  CD1   . ILE A 1 260  ? 114.826 117.400 93.811  1.00 22.12  ? 278  ILE A CD1   1 
ATOM   1564  N  N     . ARG A 1 261  ? 113.745 114.808 98.799  1.00 27.95  ? 279  ARG A N     1 
ATOM   1565  C  CA    . ARG A 1 261  ? 113.911 113.847 99.882  1.00 27.95  ? 279  ARG A CA    1 
ATOM   1566  C  C     . ARG A 1 261  ? 114.907 112.750 99.527  1.00 27.95  ? 279  ARG A C     1 
ATOM   1567  O  O     . ARG A 1 261  ? 115.808 112.442 100.315 1.00 27.95  ? 279  ARG A O     1 
ATOM   1568  C  CB    . ARG A 1 261  ? 112.557 113.238 100.232 1.00 27.95  ? 279  ARG A CB    1 
ATOM   1569  C  CG    . ARG A 1 261  ? 112.637 111.966 101.034 1.00 27.95  ? 279  ARG A CG    1 
ATOM   1570  C  CD    . ARG A 1 261  ? 111.272 111.326 101.115 1.00 27.95  ? 279  ARG A CD    1 
ATOM   1571  N  NE    . ARG A 1 261  ? 110.261 112.287 101.536 1.00 27.95  ? 279  ARG A NE    1 
ATOM   1572  C  CZ    . ARG A 1 261  ? 108.954 112.083 101.451 1.00 27.95  ? 279  ARG A CZ    1 
ATOM   1573  N  NH1   . ARG A 1 261  ? 108.461 110.964 100.948 1.00 27.95  ? 279  ARG A NH1   1 
ATOM   1574  N  NH2   . ARG A 1 261  ? 108.122 113.027 101.879 1.00 27.95  ? 279  ARG A NH2   1 
ATOM   1575  N  N     . GLU A 1 262  ? 114.765 112.152 98.344  1.00 30.52  ? 280  GLU A N     1 
ATOM   1576  C  CA    . GLU A 1 262  ? 115.600 111.020 97.962  1.00 30.52  ? 280  GLU A CA    1 
ATOM   1577  C  C     . GLU A 1 262  ? 117.060 111.392 97.757  1.00 30.52  ? 280  GLU A C     1 
ATOM   1578  O  O     . GLU A 1 262  ? 117.897 110.492 97.638  1.00 30.52  ? 280  GLU A O     1 
ATOM   1579  C  CB    . GLU A 1 262  ? 115.053 110.375 96.688  1.00 30.52  ? 280  GLU A CB    1 
ATOM   1580  C  CG    . GLU A 1 262  ? 113.763 109.598 96.886  1.00 30.52  ? 280  GLU A CG    1 
ATOM   1581  C  CD    . GLU A 1 262  ? 112.544 110.491 97.000  1.00 30.52  ? 280  GLU A CD    1 
ATOM   1582  O  OE1   . GLU A 1 262  ? 112.706 111.714 97.186  1.00 30.52  ? 280  GLU A OE1   1 
ATOM   1583  O  OE2   . GLU A 1 262  ? 111.417 109.965 96.896  1.00 30.52  ? 280  GLU A OE2   1 
ATOM   1584  N  N     . GLN A 1 263  ? 117.385 112.679 97.704  1.00 20.51  ? 281  GLN A N     1 
ATOM   1585  C  CA    . GLN A 1 263  ? 118.760 113.114 97.532  1.00 20.51  ? 281  GLN A CA    1 
ATOM   1586  C  C     . GLN A 1 263  ? 119.527 113.189 98.844  1.00 20.51  ? 281  GLN A C     1 
ATOM   1587  O  O     . GLN A 1 263  ? 120.745 113.400 98.821  1.00 20.51  ? 281  GLN A O     1 
ATOM   1588  C  CB    . GLN A 1 263  ? 118.787 114.476 96.836  1.00 20.51  ? 281  GLN A CB    1 
ATOM   1589  C  CG    . GLN A 1 263  ? 118.369 114.422 95.385  1.00 20.51  ? 281  GLN A CG    1 
ATOM   1590  C  CD    . GLN A 1 263  ? 119.470 113.901 94.494  1.00 20.51  ? 281  GLN A CD    1 
ATOM   1591  O  OE1   . GLN A 1 263  ? 120.581 114.429 94.495  1.00 20.51  ? 281  GLN A OE1   1 
ATOM   1592  N  NE2   . GLN A 1 263  ? 119.174 112.856 93.730  1.00 20.51  ? 281  GLN A NE2   1 
ATOM   1593  N  N     . TYR A 1 264  ? 118.850 113.026 99.976  1.00 17.94  ? 282  TYR A N     1 
ATOM   1594  C  CA    . TYR A 1 264  ? 119.505 112.955 101.283 1.00 17.94  ? 282  TYR A CA    1 
ATOM   1595  C  C     . TYR A 1 264  ? 119.678 111.500 101.717 1.00 17.94  ? 282  TYR A C     1 
ATOM   1596  O  O     . TYR A 1 264  ? 119.093 111.033 102.690 1.00 17.94  ? 282  TYR A O     1 
ATOM   1597  C  CB    . TYR A 1 264  ? 118.712 113.755 102.315 1.00 17.94  ? 282  TYR A CB    1 
ATOM   1598  C  CG    . TYR A 1 264  ? 119.036 115.230 102.317 1.00 17.94  ? 282  TYR A CG    1 
ATOM   1599  C  CD1   . TYR A 1 264  ? 120.193 115.698 102.916 1.00 17.94  ? 282  TYR A CD1   1 
ATOM   1600  C  CD2   . TYR A 1 264  ? 118.189 116.154 101.722 1.00 17.94  ? 282  TYR A CD2   1 
ATOM   1601  C  CE1   . TYR A 1 264  ? 120.502 117.039 102.923 1.00 17.94  ? 282  TYR A CE1   1 
ATOM   1602  C  CE2   . TYR A 1 264  ? 118.494 117.503 101.726 1.00 17.94  ? 282  TYR A CE2   1 
ATOM   1603  C  CZ    . TYR A 1 264  ? 119.655 117.937 102.330 1.00 17.94  ? 282  TYR A CZ    1 
ATOM   1604  O  OH    . TYR A 1 264  ? 119.987 119.271 102.352 1.00 17.94  ? 282  TYR A OH    1 
ATOM   1605  N  N     . LEU A 1 265  ? 120.499 110.780 100.959 1.00 21.27  ? 283  LEU A N     1 
ATOM   1606  C  CA    . LEU A 1 265  ? 120.791 109.379 101.227 1.00 21.27  ? 283  LEU A CA    1 
ATOM   1607  C  C     . LEU A 1 265  ? 122.258 109.121 100.926 1.00 21.27  ? 283  LEU A C     1 
ATOM   1608  O  O     . LEU A 1 265  ? 122.800 109.658 99.957  1.00 21.27  ? 283  LEU A O     1 
ATOM   1609  C  CB    . LEU A 1 265  ? 119.904 108.448 100.394 1.00 21.27  ? 283  LEU A CB    1 
ATOM   1610  C  CG    . LEU A 1 265  ? 118.463 108.296 100.877 1.00 21.27  ? 283  LEU A CG    1 
ATOM   1611  C  CD1   . LEU A 1 265  ? 117.645 107.461 99.905  1.00 21.27  ? 283  LEU A CD1   1 
ATOM   1612  C  CD2   . LEU A 1 265  ? 118.445 107.677 102.262 1.00 21.27  ? 283  LEU A CD2   1 
ATOM   1613  N  N     . ILE A 1 266  ? 122.894 108.294 101.757 1.00 21.67  ? 284  ILE A N     1 
ATOM   1614  C  CA    . ILE A 1 266  ? 124.343 108.139 101.675 1.00 21.67  ? 284  ILE A CA    1 
ATOM   1615  C  C     . ILE A 1 266  ? 124.739 107.399 100.404 1.00 21.67  ? 284  ILE A C     1 
ATOM   1616  O  O     . ILE A 1 266  ? 125.726 107.753 99.749  1.00 21.67  ? 284  ILE A O     1 
ATOM   1617  C  CB    . ILE A 1 266  ? 124.877 107.443 102.939 1.00 21.67  ? 284  ILE A CB    1 
ATOM   1618  C  CG1   . ILE A 1 266  ? 124.257 108.076 104.186 1.00 21.67  ? 284  ILE A CG1   1 
ATOM   1619  C  CG2   . ILE A 1 266  ? 126.385 107.558 103.001 1.00 21.67  ? 284  ILE A CG2   1 
ATOM   1620  C  CD1   . ILE A 1 266  ? 124.886 107.628 105.486 1.00 21.67  ? 284  ILE A CD1   1 
ATOM   1621  N  N     . GLN A 1 267  ? 123.989 106.367 100.032 1.00 25.14  ? 285  GLN A N     1 
ATOM   1622  C  CA    . GLN A 1 267  ? 124.254 105.692 98.772  1.00 25.14  ? 285  GLN A CA    1 
ATOM   1623  C  C     . GLN A 1 267  ? 123.935 106.617 97.603  1.00 25.14  ? 285  GLN A C     1 
ATOM   1624  O  O     . GLN A 1 267  ? 123.105 107.524 97.708  1.00 25.14  ? 285  GLN A O     1 
ATOM   1625  C  CB    . GLN A 1 267  ? 123.442 104.399 98.662  1.00 25.14  ? 285  GLN A CB    1 
ATOM   1626  C  CG    . GLN A 1 267  ? 121.953 104.593 98.423  1.00 25.14  ? 285  GLN A CG    1 
ATOM   1627  C  CD    . GLN A 1 267  ? 121.191 104.938 99.685  1.00 25.14  ? 285  GLN A CD    1 
ATOM   1628  O  OE1   . GLN A 1 267  ? 121.781 105.160 100.743 1.00 25.14  ? 285  GLN A OE1   1 
ATOM   1629  N  NE2   . GLN A 1 267  ? 119.868 104.980 99.581  1.00 25.14  ? 285  GLN A NE2   1 
ATOM   1630  N  N     . GLY A 1 268  ? 124.616 106.388 96.483  1.00 25.25  ? 286  GLY A N     1 
ATOM   1631  C  CA    . GLY A 1 268  ? 124.455 107.257 95.334  1.00 25.25  ? 286  GLY A CA    1 
ATOM   1632  C  C     . GLY A 1 268  ? 123.059 107.191 94.745  1.00 25.25  ? 286  GLY A C     1 
ATOM   1633  O  O     . GLY A 1 268  ? 122.271 106.285 95.020  1.00 25.25  ? 286  GLY A O     1 
ATOM   1634  N  N     . SER A 1 269  ? 122.755 108.185 93.916  1.00 31.60  ? 287  SER A N     1 
ATOM   1635  C  CA    . SER A 1 269  ? 121.464 108.303 93.259  1.00 31.60  ? 287  SER A CA    1 
ATOM   1636  C  C     . SER A 1 269  ? 121.657 108.305 91.750  1.00 31.60  ? 287  SER A C     1 
ATOM   1637  O  O     . SER A 1 269  ? 122.648 108.832 91.236  1.00 31.60  ? 287  SER A O     1 
ATOM   1638  C  CB    . SER A 1 269  ? 120.733 109.577 93.695  1.00 31.60  ? 287  SER A CB    1 
ATOM   1639  O  OG    . SER A 1 269  ? 119.456 109.667 93.090  1.00 31.60  ? 287  SER A OG    1 
ATOM   1640  N  N     . ARG A 1 270  ? 120.699 107.711 91.041  1.00 38.18  ? 288  ARG A N     1 
ATOM   1641  C  CA    . ARG A 1 270  ? 120.758 107.603 89.590  1.00 38.18  ? 288  ARG A CA    1 
ATOM   1642  C  C     . ARG A 1 270  ? 120.030 108.742 88.885  1.00 38.18  ? 288  ARG A C     1 
ATOM   1643  O  O     . ARG A 1 270  ? 119.903 108.717 87.657  1.00 38.18  ? 288  ARG A O     1 
ATOM   1644  C  CB    . ARG A 1 270  ? 120.193 106.253 89.141  1.00 38.18  ? 288  ARG A CB    1 
ATOM   1645  C  CG    . ARG A 1 270  ? 120.812 105.729 87.859  1.00 38.18  ? 288  ARG A CG    1 
ATOM   1646  C  CD    . ARG A 1 270  ? 120.516 104.257 87.665  1.00 38.18  ? 288  ARG A CD    1 
ATOM   1647  N  NE    . ARG A 1 270  ? 121.153 103.442 88.691  1.00 38.18  ? 288  ARG A NE    1 
ATOM   1648  C  CZ    . ARG A 1 270  ? 121.085 102.119 88.746  1.00 38.18  ? 288  ARG A CZ    1 
ATOM   1649  N  NH1   . ARG A 1 270  ? 120.407 101.423 87.849  1.00 38.18  ? 288  ARG A NH1   1 
ATOM   1650  N  NH2   . ARG A 1 270  ? 121.714 101.478 89.727  1.00 38.18  ? 288  ARG A NH2   1 
ATOM   1651  N  N     . MET A 1 271  ? 119.554 109.733 89.630  1.00 31.63  ? 289  MET A N     1 
ATOM   1652  C  CA    . MET A 1 271  ? 118.910 110.910 89.067  1.00 31.63  ? 289  MET A CA    1 
ATOM   1653  C  C     . MET A 1 271  ? 119.905 112.058 89.022  1.00 31.63  ? 289  MET A C     1 
ATOM   1654  O  O     . MET A 1 271  ? 120.536 112.376 90.034  1.00 31.63  ? 289  MET A O     1 
ATOM   1655  C  CB    . MET A 1 271  ? 117.686 111.304 89.892  1.00 31.63  ? 289  MET A CB    1 
ATOM   1656  C  CG    . MET A 1 271  ? 117.199 112.716 89.637  1.00 31.63  ? 289  MET A CG    1 
ATOM   1657  S  SD    . MET A 1 271  ? 115.788 113.154 90.664  1.00 31.63  ? 289  MET A SD    1 
ATOM   1658  C  CE    . MET A 1 271  ? 114.512 112.136 89.937  1.00 31.63  ? 289  MET A CE    1 
ATOM   1659  N  N     . ARG A 1 272  ? 120.038 112.682 87.858  1.00 26.07  ? 290  ARG A N     1 
ATOM   1660  C  CA    . ARG A 1 272  ? 120.949 113.799 87.678  1.00 26.07  ? 290  ARG A CA    1 
ATOM   1661  C  C     . ARG A 1 272  ? 120.156 115.069 87.415  1.00 26.07  ? 290  ARG A C     1 
ATOM   1662  O  O     . ARG A 1 272  ? 119.033 115.027 86.908  1.00 26.07  ? 290  ARG A O     1 
ATOM   1663  C  CB    . ARG A 1 272  ? 121.929 113.545 86.529  1.00 26.07  ? 290  ARG A CB    1 
ATOM   1664  C  CG    . ARG A 1 272  ? 122.823 112.331 86.733  1.00 26.07  ? 290  ARG A CG    1 
ATOM   1665  C  CD    . ARG A 1 272  ? 123.713 112.472 87.959  1.00 26.07  ? 290  ARG A CD    1 
ATOM   1666  N  NE    . ARG A 1 272  ? 124.475 111.256 88.214  1.00 26.07  ? 290  ARG A NE    1 
ATOM   1667  C  CZ    . ARG A 1 272  ? 124.021 110.223 88.910  1.00 26.07  ? 290  ARG A CZ    1 
ATOM   1668  N  NH1   . ARG A 1 272  ? 122.814 110.230 89.448  1.00 26.07  ? 290  ARG A NH1   1 
ATOM   1669  N  NH2   . ARG A 1 272  ? 124.796 109.154 89.066  1.00 26.07  ? 290  ARG A NH2   1 
ATOM   1670  N  N     . PHE A 1 273  ? 120.754 116.199 87.771  1.00 23.61  ? 291  PHE A N     1 
ATOM   1671  C  CA    . PHE A 1 273  ? 120.076 117.485 87.780  1.00 23.61  ? 291  PHE A CA    1 
ATOM   1672  C  C     . PHE A 1 273  ? 120.774 118.437 86.824  1.00 23.61  ? 291  PHE A C     1 
ATOM   1673  O  O     . PHE A 1 273  ? 122.001 118.576 86.864  1.00 23.61  ? 291  PHE A O     1 
ATOM   1674  C  CB    . PHE A 1 273  ? 120.043 118.066 89.195  1.00 23.61  ? 291  PHE A CB    1 
ATOM   1675  C  CG    . PHE A 1 273  ? 119.185 117.281 90.142  1.00 23.61  ? 291  PHE A CG    1 
ATOM   1676  C  CD1   . PHE A 1 273  ? 119.640 116.100 90.694  1.00 23.61  ? 291  PHE A CD1   1 
ATOM   1677  C  CD2   . PHE A 1 273  ? 117.916 117.717 90.465  1.00 23.61  ? 291  PHE A CD2   1 
ATOM   1678  C  CE1   . PHE A 1 273  ? 118.849 115.373 91.551  1.00 23.61  ? 291  PHE A CE1   1 
ATOM   1679  C  CE2   . PHE A 1 273  ? 117.125 116.995 91.322  1.00 23.61  ? 291  PHE A CE2   1 
ATOM   1680  C  CZ    . PHE A 1 273  ? 117.591 115.823 91.868  1.00 23.61  ? 291  PHE A CZ    1 
ATOM   1681  N  N     . LEU A 1 274  ? 119.990 119.090 85.973  1.00 23.39  ? 292  LEU A N     1 
ATOM   1682  C  CA    . LEU A 1 274  ? 120.497 120.030 84.987  1.00 23.39  ? 292  LEU A CA    1 
ATOM   1683  C  C     . LEU A 1 274  ? 119.883 121.394 85.256  1.00 23.39  ? 292  LEU A C     1 
ATOM   1684  O  O     . LEU A 1 274  ? 118.679 121.506 85.496  1.00 23.39  ? 292  LEU A O     1 
ATOM   1685  C  CB    . LEU A 1 274  ? 120.182 119.559 83.564  1.00 23.39  ? 292  LEU A CB    1 
ATOM   1686  C  CG    . LEU A 1 274  ? 120.862 120.291 82.410  1.00 23.39  ? 292  LEU A CG    1 
ATOM   1687  C  CD1   . LEU A 1 274  ? 122.310 120.586 82.746  1.00 23.39  ? 292  LEU A CD1   1 
ATOM   1688  C  CD2   . LEU A 1 274  ? 120.772 119.444 81.159  1.00 23.39  ? 292  LEU A CD2   1 
ATOM   1689  N  N     . ASP A 1 275  ? 120.715 122.428 85.218  1.00 26.86  ? 293  ASP A N     1 
ATOM   1690  C  CA    . ASP A 1 275  ? 120.343 123.748 85.704  1.00 26.86  ? 293  ASP A CA    1 
ATOM   1691  C  C     . ASP A 1 275  ? 120.327 124.735 84.549  1.00 26.86  ? 293  ASP A C     1 
ATOM   1692  O  O     . ASP A 1 275  ? 121.316 124.859 83.819  1.00 26.86  ? 293  ASP A O     1 
ATOM   1693  C  CB    . ASP A 1 275  ? 121.313 124.215 86.791  1.00 26.86  ? 293  ASP A CB    1 
ATOM   1694  C  CG    . ASP A 1 275  ? 120.684 125.198 87.750  1.00 26.86  ? 293  ASP A CG    1 
ATOM   1695  O  OD1   . ASP A 1 275  ? 120.055 126.170 87.282  1.00 26.86  ? 293  ASP A OD1   1 
ATOM   1696  O  OD2   . ASP A 1 275  ? 120.812 124.991 88.975  1.00 26.86  ? 293  ASP A OD2   1 
ATOM   1697  N  N     . THR A 1 276  ? 119.205 125.438 84.394  1.00 28.55  ? 294  THR A N     1 
ATOM   1698  C  CA    . THR A 1 276  ? 119.095 126.432 83.334  1.00 28.55  ? 294  THR A CA    1 
ATOM   1699  C  C     . THR A 1 276  ? 120.044 127.599 83.566  1.00 28.55  ? 294  THR A C     1 
ATOM   1700  O  O     . THR A 1 276  ? 120.585 128.155 82.606  1.00 28.55  ? 294  THR A O     1 
ATOM   1701  C  CB    . THR A 1 276  ? 117.651 126.924 83.232  1.00 28.55  ? 294  THR A CB    1 
ATOM   1702  O  OG1   . THR A 1 276  ? 116.825 125.870 82.722  1.00 28.55  ? 294  THR A OG1   1 
ATOM   1703  C  CG2   . THR A 1 276  ? 117.552 128.122 82.316  1.00 28.55  ? 294  THR A CG2   1 
ATOM   1704  N  N     . MET A 1 277  ? 120.271 127.973 84.825  1.00 33.06  ? 295  MET A N     1 
ATOM   1705  C  CA    . MET A 1 277  ? 121.237 129.026 85.111  1.00 33.06  ? 295  MET A CA    1 
ATOM   1706  C  C     . MET A 1 277  ? 122.639 128.612 84.683  1.00 33.06  ? 295  MET A C     1 
ATOM   1707  O  O     . MET A 1 277  ? 123.383 129.413 84.109  1.00 33.06  ? 295  MET A O     1 
ATOM   1708  C  CB    . MET A 1 277  ? 121.214 129.375 86.598  1.00 33.06  ? 295  MET A CB    1 
ATOM   1709  C  CG    . MET A 1 277  ? 122.150 130.511 86.973  1.00 33.06  ? 295  MET A CG    1 
ATOM   1710  S  SD    . MET A 1 277  ? 122.287 130.764 88.751  1.00 33.06  ? 295  MET A SD    1 
ATOM   1711  C  CE    . MET A 1 277  ? 120.581 131.079 89.185  1.00 33.06  ? 295  MET A CE    1 
ATOM   1712  N  N     . SER A 1 278  ? 123.010 127.356 84.942  1.00 28.31  ? 296  SER A N     1 
ATOM   1713  C  CA    . SER A 1 278  ? 124.335 126.876 84.567  1.00 28.31  ? 296  SER A CA    1 
ATOM   1714  C  C     . SER A 1 278  ? 124.509 126.857 83.052  1.00 28.31  ? 296  SER A C     1 
ATOM   1715  O  O     . SER A 1 278  ? 125.533 127.311 82.526  1.00 28.31  ? 296  SER A O     1 
ATOM   1716  C  CB    . SER A 1 278  ? 124.563 125.484 85.152  1.00 28.31  ? 296  SER A CB    1 
ATOM   1717  O  OG    . SER A 1 278  ? 123.644 124.553 84.608  1.00 28.31  ? 296  SER A OG    1 
ATOM   1718  N  N     . MET A 1 279  ? 123.514 126.334 82.330  1.00 29.10  ? 297  MET A N     1 
ATOM   1719  C  CA    . MET A 1 279  ? 123.608 126.297 80.874  1.00 29.10  ? 297  MET A CA    1 
ATOM   1720  C  C     . MET A 1 279  ? 123.611 127.700 80.285  1.00 29.10  ? 297  MET A C     1 
ATOM   1721  O  O     . MET A 1 279  ? 124.310 127.964 79.302  1.00 29.10  ? 297  MET A O     1 
ATOM   1722  C  CB    . MET A 1 279  ? 122.467 125.469 80.291  1.00 29.10  ? 297  MET A CB    1 
ATOM   1723  C  CG    . MET A 1 279  ? 122.503 124.018 80.708  1.00 29.10  ? 297  MET A CG    1 
ATOM   1724  S  SD    . MET A 1 279  ? 121.532 122.947 79.637  1.00 29.10  ? 297  MET A SD    1 
ATOM   1725  C  CE    . MET A 1 279  ? 119.908 123.671 79.821  1.00 29.10  ? 297  MET A CE    1 
ATOM   1726  N  N     . HIS A 1 280  ? 122.829 128.613 80.865  1.00 35.31  ? 298  HIS A N     1 
ATOM   1727  C  CA    . HIS A 1 280  ? 122.868 130.003 80.424  1.00 35.31  ? 298  HIS A CA    1 
ATOM   1728  C  C     . HIS A 1 280  ? 124.243 130.609 80.643  1.00 35.31  ? 298  HIS A C     1 
ATOM   1729  O  O     . HIS A 1 280  ? 124.761 131.325 79.780  1.00 35.31  ? 298  HIS A O     1 
ATOM   1730  C  CB    . HIS A 1 280  ? 121.814 130.823 81.163  1.00 35.31  ? 298  HIS A CB    1 
ATOM   1731  C  CG    . HIS A 1 280  ? 122.088 132.294 81.158  1.00 35.31  ? 298  HIS A CG    1 
ATOM   1732  N  ND1   . HIS A 1 280  ? 122.247 133.017 79.996  1.00 35.31  ? 298  HIS A ND1   1 
ATOM   1733  C  CD2   . HIS A 1 280  ? 122.243 133.176 82.173  1.00 35.31  ? 298  HIS A CD2   1 
ATOM   1734  C  CE1   . HIS A 1 280  ? 122.484 134.281 80.295  1.00 35.31  ? 298  HIS A CE1   1 
ATOM   1735  N  NE2   . HIS A 1 280  ? 122.487 134.404 81.609  1.00 35.31  ? 298  HIS A NE2   1 
ATOM   1736  N  N     . MET A 1 281  ? 124.846 130.342 81.800  1.00 33.88  ? 299  MET A N     1 
ATOM   1737  C  CA    . MET A 1 281  ? 126.167 130.882 82.087  1.00 33.88  ? 299  MET A CA    1 
ATOM   1738  C  C     . MET A 1 281  ? 127.209 130.291 81.147  1.00 33.88  ? 299  MET A C     1 
ATOM   1739  O  O     . MET A 1 281  ? 128.206 130.945 80.821  1.00 33.88  ? 299  MET A O     1 
ATOM   1740  C  CB    . MET A 1 281  ? 126.524 130.606 83.546  1.00 33.88  ? 299  MET A CB    1 
ATOM   1741  C  CG    . MET A 1 281  ? 127.453 131.623 84.171  1.00 33.88  ? 299  MET A CG    1 
ATOM   1742  S  SD    . MET A 1 281  ? 126.744 133.274 84.249  1.00 33.88  ? 299  MET A SD    1 
ATOM   1743  C  CE    . MET A 1 281  ? 127.932 134.094 85.307  1.00 33.88  ? 299  MET A CE    1 
ATOM   1744  N  N     . ALA A 1 282  ? 126.993 129.052 80.707  1.00 33.50  ? 300  ALA A N     1 
ATOM   1745  C  CA    . ALA A 1 282  ? 127.885 128.449 79.722  1.00 33.50  ? 300  ALA A CA    1 
ATOM   1746  C  C     . ALA A 1 282  ? 127.711 129.087 78.348  1.00 33.50  ? 300  ALA A C     1 
ATOM   1747  O  O     . ALA A 1 282  ? 128.697 129.391 77.668  1.00 33.50  ? 300  ALA A O     1 
ATOM   1748  C  CB    . ALA A 1 282  ? 127.639 126.943 79.648  1.00 33.50  ? 300  ALA A CB    1 
ATOM   1749  N  N     . ILE A 1 283  ? 126.465 129.302 77.928  1.00 34.03  ? 301  ILE A N     1 
ATOM   1750  C  CA    . ILE A 1 283  ? 126.160 129.746 76.572  1.00 34.03  ? 301  ILE A CA    1 
ATOM   1751  C  C     . ILE A 1 283  ? 126.428 131.235 76.406  1.00 34.03  ? 301  ILE A C     1 
ATOM   1752  O  O     . ILE A 1 283  ? 127.292 131.636 75.620  1.00 34.03  ? 301  ILE A O     1 
ATOM   1753  C  CB    . ILE A 1 283  ? 124.699 129.423 76.215  1.00 34.03  ? 301  ILE A CB    1 
ATOM   1754  C  CG1   . ILE A 1 283  ? 124.472 127.916 76.207  1.00 34.03  ? 301  ILE A CG1   1 
ATOM   1755  C  CG2   . ILE A 1 283  ? 124.333 130.021 74.871  1.00 34.03  ? 301  ILE A CG2   1 
ATOM   1756  C  CD1   . ILE A 1 283  ? 123.023 127.539 76.177  1.00 34.03  ? 301  ILE A CD1   1 
ATOM   1757  N  N     . SER A 1 284  ? 125.696 132.063 77.146  1.00 36.12  ? 302  SER A N     1 
ATOM   1758  C  CA    . SER A 1 284  ? 125.750 133.516 77.011  1.00 36.12  ? 302  SER A CA    1 
ATOM   1759  C  C     . SER A 1 284  ? 125.851 134.175 78.377  1.00 36.12  ? 302  SER A C     1 
ATOM   1760  O  O     . SER A 1 284  ? 125.138 135.130 78.691  1.00 36.12  ? 302  SER A O     1 
ATOM   1761  C  CB    . SER A 1 284  ? 124.532 134.038 76.259  1.00 36.12  ? 302  SER A CB    1 
ATOM   1762  O  OG    . SER A 1 284  ? 123.351 133.838 77.014  1.00 36.12  ? 302  SER A OG    1 
ATOM   1763  N  N     . GLY A 1 285  ? 126.744 133.664 79.216  1.00 36.31  ? 303  GLY A N     1 
ATOM   1764  C  CA    . GLY A 1 285  ? 126.906 134.220 80.540  1.00 36.31  ? 303  GLY A CA    1 
ATOM   1765  C  C     . GLY A 1 285  ? 127.664 135.531 80.527  1.00 36.31  ? 303  GLY A C     1 
ATOM   1766  O  O     . GLY A 1 285  ? 128.295 135.918 79.544  1.00 36.31  ? 303  GLY A O     1 
ATOM   1767  N  N     . LEU A 1 286  ? 127.594 136.227 81.656  1.00 45.36  ? 304  LEU A N     1 
ATOM   1768  C  CA    . LEU A 1 286  ? 128.263 137.504 81.844  1.00 45.36  ? 304  LEU A CA    1 
ATOM   1769  C  C     . LEU A 1 286  ? 129.261 137.396 82.985  1.00 45.36  ? 304  LEU A C     1 
ATOM   1770  O  O     . LEU A 1 286  ? 128.947 136.845 84.043  1.00 45.36  ? 304  LEU A O     1 
ATOM   1771  C  CB    . LEU A 1 286  ? 127.260 138.618 82.162  1.00 45.36  ? 304  LEU A CB    1 
ATOM   1772  C  CG    . LEU A 1 286  ? 126.254 139.062 81.103  1.00 45.36  ? 304  LEU A CG    1 
ATOM   1773  C  CD1   . LEU A 1 286  ? 125.241 139.999 81.725  1.00 45.36  ? 304  LEU A CD1   1 
ATOM   1774  C  CD2   . LEU A 1 286  ? 126.969 139.745 79.961  1.00 45.36  ? 304  LEU A CD2   1 
ATOM   1775  N  N     . SER A 1 287  ? 130.460 137.929 82.775  1.00 53.51  ? 305  SER A N     1 
ATOM   1776  C  CA    . SER A 1 287  ? 131.359 138.120 83.898  1.00 53.51  ? 305  SER A CA    1 
ATOM   1777  C  C     . SER A 1 287  ? 130.768 139.160 84.849  1.00 53.51  ? 305  SER A C     1 
ATOM   1778  O  O     . SER A 1 287  ? 129.832 139.890 84.510  1.00 53.51  ? 305  SER A O     1 
ATOM   1779  C  CB    . SER A 1 287  ? 132.746 138.539 83.413  1.00 53.51  ? 305  SER A CB    1 
ATOM   1780  O  OG    . SER A 1 287  ? 132.657 139.452 82.336  1.00 53.51  ? 305  SER A OG    1 
ATOM   1781  N  N     . SER A 1 288  ? 131.320 139.218 86.063  1.00 63.26  ? 306  SER A N     1 
ATOM   1782  C  CA    . SER A 1 288  ? 130.774 140.123 87.069  1.00 63.26  ? 306  SER A CA    1 
ATOM   1783  C  C     . SER A 1 288  ? 130.844 141.572 86.604  1.00 63.26  ? 306  SER A C     1 
ATOM   1784  O  O     . SER A 1 288  ? 129.908 142.349 86.827  1.00 63.26  ? 306  SER A O     1 
ATOM   1785  C  CB    . SER A 1 288  ? 131.510 139.944 88.396  1.00 63.26  ? 306  SER A CB    1 
ATOM   1786  O  OG    . SER A 1 288  ? 131.230 138.676 88.961  1.00 63.26  ? 306  SER A OG    1 
ATOM   1787  N  N     . PHE A 1 289  ? 131.942 141.952 85.950  1.00 76.55  ? 307  PHE A N     1 
ATOM   1788  C  CA    . PHE A 1 289  ? 132.019 143.282 85.355  1.00 76.55  ? 307  PHE A CA    1 
ATOM   1789  C  C     . PHE A 1 289  ? 130.991 143.446 84.242  1.00 76.55  ? 307  PHE A C     1 
ATOM   1790  O  O     . PHE A 1 289  ? 130.353 144.499 84.124  1.00 76.55  ? 307  PHE A O     1 
ATOM   1791  C  CB    . PHE A 1 289  ? 133.429 143.536 84.828  1.00 76.55  ? 307  PHE A CB    1 
ATOM   1792  C  CG    . PHE A 1 289  ? 133.686 144.964 84.454  1.00 76.55  ? 307  PHE A CG    1 
ATOM   1793  C  CD1   . PHE A 1 289  ? 134.016 145.897 85.422  1.00 76.55  ? 307  PHE A CD1   1 
ATOM   1794  C  CD2   . PHE A 1 289  ? 133.604 145.374 83.136  1.00 76.55  ? 307  PHE A CD2   1 
ATOM   1795  C  CE1   . PHE A 1 289  ? 134.256 147.214 85.082  1.00 76.55  ? 307  PHE A CE1   1 
ATOM   1796  C  CE2   . PHE A 1 289  ? 133.845 146.690 82.788  1.00 76.55  ? 307  PHE A CE2   1 
ATOM   1797  C  CZ    . PHE A 1 289  ? 134.170 147.611 83.763  1.00 76.55  ? 307  PHE A CZ    1 
ATOM   1798  N  N     . GLN A 1 290  ? 130.813 142.413 83.416  1.00 57.62  ? 308  GLN A N     1 
ATOM   1799  C  CA    . GLN A 1 290  ? 129.786 142.469 82.381  1.00 57.62  ? 308  GLN A CA    1 
ATOM   1800  C  C     . GLN A 1 290  ? 128.386 142.469 82.979  1.00 57.62  ? 308  GLN A C     1 
ATOM   1801  O  O     . GLN A 1 290  ? 127.481 143.102 82.426  1.00 57.62  ? 308  GLN A O     1 
ATOM   1802  C  CB    . GLN A 1 290  ? 129.947 141.305 81.405  1.00 57.62  ? 308  GLN A CB    1 
ATOM   1803  C  CG    . GLN A 1 290  ? 131.054 141.502 80.386  1.00 57.62  ? 308  GLN A CG    1 
ATOM   1804  C  CD    . GLN A 1 290  ? 130.988 140.493 79.261  1.00 57.62  ? 308  GLN A CD    1 
ATOM   1805  O  OE1   . GLN A 1 290  ? 130.207 139.544 79.309  1.00 57.62  ? 308  GLN A OE1   1 
ATOM   1806  N  NE2   . GLN A 1 290  ? 131.804 140.697 78.235  1.00 57.62  ? 308  GLN A NE2   1 
ATOM   1807  N  N     . ARG A 1 291  ? 128.187 141.772 84.100  1.00 65.86  ? 309  ARG A N     1 
ATOM   1808  C  CA    . ARG A 1 291  ? 126.904 141.851 84.791  1.00 65.86  ? 309  ARG A CA    1 
ATOM   1809  C  C     . ARG A 1 291  ? 126.638 143.265 85.293  1.00 65.86  ? 309  ARG A C     1 
ATOM   1810  O  O     . ARG A 1 291  ? 125.516 143.771 85.182  1.00 65.86  ? 309  ARG A O     1 
ATOM   1811  C  CB    . ARG A 1 291  ? 126.868 140.862 85.954  1.00 65.86  ? 309  ARG A CB    1 
ATOM   1812  C  CG    . ARG A 1 291  ? 125.723 141.105 86.916  1.00 65.86  ? 309  ARG A CG    1 
ATOM   1813  C  CD    . ARG A 1 291  ? 126.009 140.507 88.275  1.00 65.86  ? 309  ARG A CD    1 
ATOM   1814  N  NE    . ARG A 1 291  ? 125.941 139.052 88.262  1.00 65.86  ? 309  ARG A NE    1 
ATOM   1815  C  CZ    . ARG A 1 291  ? 126.184 138.285 89.316  1.00 65.86  ? 309  ARG A CZ    1 
ATOM   1816  N  NH1   . ARG A 1 291  ? 126.523 138.804 90.485  1.00 65.86  ? 309  ARG A NH1   1 
ATOM   1817  N  NH2   . ARG A 1 291  ? 126.083 136.965 89.195  1.00 65.86  ? 309  ARG A NH2   1 
ATOM   1818  N  N     . SER A 1 292  ? 127.661 143.914 85.853  1.00 67.19  ? 310  SER A N     1 
ATOM   1819  C  CA    . SER A 1 292  ? 127.508 145.292 86.309  1.00 67.19  ? 310  SER A CA    1 
ATOM   1820  C  C     . SER A 1 292  ? 127.200 146.229 85.149  1.00 67.19  ? 310  SER A C     1 
ATOM   1821  O  O     . SER A 1 292  ? 126.339 147.109 85.263  1.00 67.19  ? 310  SER A O     1 
ATOM   1822  C  CB    . SER A 1 292  ? 128.772 145.743 87.039  1.00 67.19  ? 310  SER A CB    1 
ATOM   1823  O  OG    . SER A 1 292  ? 128.741 147.134 87.293  1.00 67.19  ? 310  SER A OG    1 
ATOM   1824  N  N     . LEU A 1 293  ? 127.899 146.060 84.026  1.00 53.09  ? 311  LEU A N     1 
ATOM   1825  C  CA    . LEU A 1 293  ? 127.652 146.897 82.859  1.00 53.09  ? 311  LEU A CA    1 
ATOM   1826  C  C     . LEU A 1 293  ? 126.303 146.616 82.214  1.00 53.09  ? 311  LEU A C     1 
ATOM   1827  O  O     . LEU A 1 293  ? 125.763 147.491 81.530  1.00 53.09  ? 311  LEU A O     1 
ATOM   1828  C  CB    . LEU A 1 293  ? 128.762 146.706 81.827  1.00 53.09  ? 311  LEU A CB    1 
ATOM   1829  C  CG    . LEU A 1 293  ? 129.899 147.728 81.840  1.00 53.09  ? 311  LEU A CG    1 
ATOM   1830  C  CD1   . LEU A 1 293  ? 130.525 147.835 83.220  1.00 53.09  ? 311  LEU A CD1   1 
ATOM   1831  C  CD2   . LEU A 1 293  ? 130.943 147.359 80.802  1.00 53.09  ? 311  LEU A CD2   1 
ATOM   1832  N  N     . TRP A 1 294  ? 125.751 145.420 82.409  1.00 46.81  ? 312  TRP A N     1 
ATOM   1833  C  CA    . TRP A 1 294  ? 124.484 145.078 81.779  1.00 46.81  ? 312  TRP A CA    1 
ATOM   1834  C  C     . TRP A 1 294  ? 123.299 145.725 82.483  1.00 46.81  ? 312  TRP A C     1 
ATOM   1835  O  O     . TRP A 1 294  ? 122.303 146.056 81.831  1.00 46.81  ? 312  TRP A O     1 
ATOM   1836  C  CB    . TRP A 1 294  ? 124.317 143.560 81.744  1.00 46.81  ? 312  TRP A CB    1 
ATOM   1837  C  CG    . TRP A 1 294  ? 123.254 143.091 80.816  1.00 46.81  ? 312  TRP A CG    1 
ATOM   1838  C  CD1   . TRP A 1 294  ? 123.382 142.838 79.484  1.00 46.81  ? 312  TRP A CD1   1 
ATOM   1839  C  CD2   . TRP A 1 294  ? 121.895 142.804 81.151  1.00 46.81  ? 312  TRP A CD2   1 
ATOM   1840  N  NE1   . TRP A 1 294  ? 122.184 142.414 78.965  1.00 46.81  ? 312  TRP A NE1   1 
ATOM   1841  C  CE2   . TRP A 1 294  ? 121.254 142.385 79.970  1.00 46.81  ? 312  TRP A CE2   1 
ATOM   1842  C  CE3   . TRP A 1 294  ? 121.157 142.865 82.335  1.00 46.81  ? 312  TRP A CE3   1 
ATOM   1843  C  CZ2   . TRP A 1 294  ? 119.909 142.028 79.939  1.00 46.81  ? 312  TRP A CZ2   1 
ATOM   1844  C  CZ3   . TRP A 1 294  ? 119.825 142.509 82.303  1.00 46.81  ? 312  TRP A CZ3   1 
ATOM   1845  C  CH2   . TRP A 1 294  ? 119.213 142.097 81.114  1.00 46.81  ? 312  TRP A CH2   1 
ATOM   1846  N  N     . ILE A 1 295  ? 123.385 145.916 83.796  1.00 44.17  ? 313  ILE A N     1 
ATOM   1847  C  CA    . ILE A 1 295  ? 122.318 146.565 84.547  1.00 44.17  ? 313  ILE A CA    1 
ATOM   1848  C  C     . ILE A 1 295  ? 122.485 148.078 84.500  1.00 44.17  ? 313  ILE A C     1 
ATOM   1849  O  O     . ILE A 1 295  ? 121.925 148.747 83.631  1.00 44.17  ? 313  ILE A O     1 
ATOM   1850  C  CB    . ILE A 1 295  ? 122.277 146.065 86.001  1.00 44.17  ? 313  ILE A CB    1 
ATOM   1851  C  CG1   . ILE A 1 295  ? 121.701 144.649 86.062  1.00 44.17  ? 313  ILE A CG1   1 
ATOM   1852  C  CG2   . ILE A 1 295  ? 121.471 147.017 86.871  1.00 44.17  ? 313  ILE A CG2   1 
ATOM   1853  C  CD1   . ILE A 1 295  ? 121.521 144.122 87.467  1.00 44.17  ? 313  ILE A CD1   1 
ATOM   1854  N  N     . TRP A 1 329  ? 127.164 143.000 72.396  1.00 56.61  ? 347  TRP A N     1 
ATOM   1855  C  CA    . TRP A 1 329  ? 127.020 141.799 73.210  1.00 56.61  ? 347  TRP A CA    1 
ATOM   1856  C  C     . TRP A 1 329  ? 125.869 141.939 74.199  1.00 56.61  ? 347  TRP A C     1 
ATOM   1857  O  O     . TRP A 1 329  ? 125.471 140.970 74.844  1.00 56.61  ? 347  TRP A O     1 
ATOM   1858  C  CB    . TRP A 1 329  ? 128.319 141.499 73.958  1.00 56.61  ? 347  TRP A CB    1 
ATOM   1859  C  CG    . TRP A 1 329  ? 128.814 142.635 74.802  1.00 56.61  ? 347  TRP A CG    1 
ATOM   1860  C  CD1   . TRP A 1 329  ? 129.717 143.590 74.441  1.00 56.61  ? 347  TRP A CD1   1 
ATOM   1861  C  CD2   . TRP A 1 329  ? 128.437 142.930 76.152  1.00 56.61  ? 347  TRP A CD2   1 
ATOM   1862  N  NE1   . TRP A 1 329  ? 129.927 144.462 75.481  1.00 56.61  ? 347  TRP A NE1   1 
ATOM   1863  C  CE2   . TRP A 1 329  ? 129.152 144.079 76.543  1.00 56.61  ? 347  TRP A CE2   1 
ATOM   1864  C  CE3   . TRP A 1 329  ? 127.564 142.335 77.068  1.00 56.61  ? 347  TRP A CE3   1 
ATOM   1865  C  CZ2   . TRP A 1 329  ? 129.020 144.645 77.809  1.00 56.61  ? 347  TRP A CZ2   1 
ATOM   1866  C  CZ3   . TRP A 1 329  ? 127.435 142.899 78.323  1.00 56.61  ? 347  TRP A CZ3   1 
ATOM   1867  C  CH2   . TRP A 1 329  ? 128.159 144.041 78.682  1.00 56.61  ? 347  TRP A CH2   1 
ATOM   1868  N  N     . LEU A 1 330  ? 125.342 143.159 74.314  1.00 52.79  ? 348  LEU A N     1 
ATOM   1869  C  CA    . LEU A 1 330  ? 124.250 143.408 75.249  1.00 52.79  ? 348  LEU A CA    1 
ATOM   1870  C  C     . LEU A 1 330  ? 122.964 142.722 74.808  1.00 52.79  ? 348  LEU A C     1 
ATOM   1871  O  O     . LEU A 1 330  ? 122.159 142.318 75.654  1.00 52.79  ? 348  LEU A O     1 
ATOM   1872  C  CB    . LEU A 1 330  ? 124.034 144.912 75.402  1.00 52.79  ? 348  LEU A CB    1 
ATOM   1873  C  CG    . LEU A 1 330  ? 125.148 145.654 76.139  1.00 52.79  ? 348  LEU A CG    1 
ATOM   1874  C  CD1   . LEU A 1 330  ? 125.251 147.092 75.665  1.00 52.79  ? 348  LEU A CD1   1 
ATOM   1875  C  CD2   . LEU A 1 330  ? 124.900 145.603 77.635  1.00 52.79  ? 348  LEU A CD2   1 
ATOM   1876  N  N     . ASP A 1 331  ? 122.756 142.579 73.502  1.00 61.22  ? 349  ASP A N     1 
ATOM   1877  C  CA    . ASP A 1 331  ? 121.554 141.949 72.974  1.00 61.22  ? 349  ASP A CA    1 
ATOM   1878  C  C     . ASP A 1 331  ? 121.659 140.432 72.911  1.00 61.22  ? 349  ASP A C     1 
ATOM   1879  O  O     . ASP A 1 331  ? 120.688 139.776 72.520  1.00 61.22  ? 349  ASP A O     1 
ATOM   1880  C  CB    . ASP A 1 331  ? 121.245 142.499 71.579  1.00 61.22  ? 349  ASP A CB    1 
ATOM   1881  C  CG    . ASP A 1 331  ? 121.176 144.013 71.553  1.00 61.22  ? 349  ASP A CG    1 
ATOM   1882  O  OD1   . ASP A 1 331  ? 120.764 144.609 72.570  1.00 61.22  ? 349  ASP A OD1   1 
ATOM   1883  O  OD2   . ASP A 1 331  ? 121.536 144.608 70.515  1.00 61.22  ? 349  ASP A OD2   1 
ATOM   1884  N  N     . ILE A 1 332  ? 122.805 139.862 73.281  1.00 50.00  ? 350  ILE A N     1 
ATOM   1885  C  CA    . ILE A 1 332  ? 123.042 138.427 73.183  1.00 50.00  ? 350  ILE A CA    1 
ATOM   1886  C  C     . ILE A 1 332  ? 123.258 137.781 74.542  1.00 50.00  ? 350  ILE A C     1 
ATOM   1887  O  O     . ILE A 1 332  ? 123.387 136.551 74.619  1.00 50.00  ? 350  ILE A O     1 
ATOM   1888  C  CB    . ILE A 1 332  ? 124.230 138.131 72.245  1.00 50.00  ? 350  ILE A CB    1 
ATOM   1889  C  CG1   . ILE A 1 332  ? 124.099 136.743 71.616  1.00 50.00  ? 350  ILE A CG1   1 
ATOM   1890  C  CG2   . ILE A 1 332  ? 125.551 138.279 72.983  1.00 50.00  ? 350  ILE A CG2   1 
ATOM   1891  C  CD1   . ILE A 1 332  ? 122.901 136.603 70.712  1.00 50.00  ? 350  ILE A CD1   1 
ATOM   1892  N  N     . SER A 1 333  ? 123.273 138.564 75.619  1.00 46.60  ? 351  SER A N     1 
ATOM   1893  C  CA    . SER A 1 333  ? 123.536 138.053 76.956  1.00 46.60  ? 351  SER A CA    1 
ATOM   1894  C  C     . SER A 1 333  ? 122.584 138.711 77.946  1.00 46.60  ? 351  SER A C     1 
ATOM   1895  O  O     . SER A 1 333  ? 121.892 139.680 77.626  1.00 46.60  ? 351  SER A O     1 
ATOM   1896  C  CB    . SER A 1 333  ? 124.992 138.297 77.365  1.00 46.60  ? 351  SER A CB    1 
ATOM   1897  O  OG    . SER A 1 333  ? 125.339 139.663 77.220  1.00 46.60  ? 351  SER A OG    1 
ATOM   1898  N  N     . SER A 1 334  ? 122.608 138.193 79.172  1.00 44.65  ? 352  SER A N     1 
ATOM   1899  C  CA    . SER A 1 334  ? 121.782 138.750 80.223  1.00 44.65  ? 352  SER A CA    1 
ATOM   1900  C  C     . SER A 1 334  ? 122.330 138.362 81.570  1.00 44.65  ? 352  SER A C     1 
ATOM   1901  O  O     . SER A 1 334  ? 123.306 137.626 81.655  1.00 44.65  ? 352  SER A O     1 
ATOM   1902  C  CB    . SER A 1 334  ? 120.353 138.229 80.123  1.00 44.65  ? 352  SER A CB    1 
ATOM   1903  O  OG    . SER A 1 334  ? 120.219 136.978 80.772  1.00 44.65  ? 352  SER A OG    1 
ATOM   1904  N  N     . VAL A 1 335  ? 121.722 138.861 82.630  1.00 51.05  ? 353  VAL A N     1 
ATOM   1905  C  CA    . VAL A 1 335  ? 122.093 138.494 83.991  1.00 51.05  ? 353  VAL A CA    1 
ATOM   1906  C  C     . VAL A 1 335  ? 121.353 137.222 84.382  1.00 51.05  ? 353  VAL A C     1 
ATOM   1907  O  O     . VAL A 1 335  ? 120.421 136.796 83.693  1.00 51.05  ? 353  VAL A O     1 
ATOM   1908  C  CB    . VAL A 1 335  ? 121.811 139.635 84.985  1.00 51.05  ? 353  VAL A CB    1 
ATOM   1909  C  CG1   . VAL A 1 335  ? 122.748 140.800 84.722  1.00 51.05  ? 353  VAL A CG1   1 
ATOM   1910  C  CG2   . VAL A 1 335  ? 120.364 140.076 84.893  1.00 51.05  ? 353  VAL A CG2   1 
ATOM   1911  N  N     . ASN A 1 336  ? 121.764 136.613 85.495  1.00 55.84  ? 354  ASN A N     1 
ATOM   1912  C  CA    . ASN A 1 336  ? 121.340 135.262 85.839  1.00 55.84  ? 354  ASN A CA    1 
ATOM   1913  C  C     . ASN A 1 336  ? 119.872 135.162 86.232  1.00 55.84  ? 354  ASN A C     1 
ATOM   1914  O  O     . ASN A 1 336  ? 119.360 134.043 86.336  1.00 55.84  ? 354  ASN A O     1 
ATOM   1915  C  CB    . ASN A 1 336  ? 122.210 134.724 86.977  1.00 55.84  ? 354  ASN A CB    1 
ATOM   1916  C  CG    . ASN A 1 336  ? 123.693 134.801 86.666  1.00 55.84  ? 354  ASN A CG    1 
ATOM   1917  O  OD1   . ASN A 1 336  ? 124.284 133.842 86.171  1.00 55.84  ? 354  ASN A OD1   1 
ATOM   1918  N  ND2   . ASN A 1 336  ? 124.302 135.945 86.956  1.00 55.84  ? 354  ASN A ND2   1 
ATOM   1919  N  N     . SER A 1 337  ? 119.191 136.284 86.456  1.00 54.74  ? 355  SER A N     1 
ATOM   1920  C  CA    . SER A 1 337  ? 117.805 136.239 86.903  1.00 54.74  ? 355  SER A CA    1 
ATOM   1921  C  C     . SER A 1 337  ? 116.903 135.644 85.827  1.00 54.74  ? 355  SER A C     1 
ATOM   1922  O  O     . SER A 1 337  ? 117.127 135.823 84.629  1.00 54.74  ? 355  SER A O     1 
ATOM   1923  C  CB    . SER A 1 337  ? 117.325 137.640 87.277  1.00 54.74  ? 355  SER A CB    1 
ATOM   1924  O  OG    . SER A 1 337  ? 118.142 138.207 88.286  1.00 54.74  ? 355  SER A OG    1 
ATOM   1925  N  N     . LEU A 1 338  ? 115.859 134.940 86.274  1.00 41.55  ? 356  LEU A N     1 
ATOM   1926  C  CA    . LEU A 1 338  ? 115.002 134.199 85.350  1.00 41.55  ? 356  LEU A CA    1 
ATOM   1927  C  C     . LEU A 1 338  ? 114.318 135.123 84.351  1.00 41.55  ? 356  LEU A C     1 
ATOM   1928  O  O     . LEU A 1 338  ? 114.222 134.797 83.162  1.00 41.55  ? 356  LEU A O     1 
ATOM   1929  C  CB    . LEU A 1 338  ? 113.961 133.397 86.130  1.00 41.55  ? 356  LEU A CB    1 
ATOM   1930  C  CG    . LEU A 1 338  ? 112.920 132.624 85.320  1.00 41.55  ? 356  LEU A CG    1 
ATOM   1931  C  CD1   . LEU A 1 338  ? 113.594 131.718 84.306  1.00 41.55  ? 356  LEU A CD1   1 
ATOM   1932  C  CD2   . LEU A 1 338  ? 112.023 131.819 86.244  1.00 41.55  ? 356  LEU A CD2   1 
ATOM   1933  N  N     . ALA A 1 339  ? 113.826 136.273 84.815  1.00 45.17  ? 357  ALA A N     1 
ATOM   1934  C  CA    . ALA A 1 339  ? 113.110 137.185 83.928  1.00 45.17  ? 357  ALA A CA    1 
ATOM   1935  C  C     . ALA A 1 339  ? 114.022 137.709 82.825  1.00 45.17  ? 357  ALA A C     1 
ATOM   1936  O  O     . ALA A 1 339  ? 113.648 137.721 81.647  1.00 45.17  ? 357  ALA A O     1 
ATOM   1937  C  CB    . ALA A 1 339  ? 112.518 138.339 84.734  1.00 45.17  ? 357  ALA A CB    1 
ATOM   1938  N  N     . GLU A 1 340  ? 115.231 138.138 83.191  1.00 47.01  ? 358  GLU A N     1 
ATOM   1939  C  CA    . GLU A 1 340  ? 116.164 138.658 82.199  1.00 47.01  ? 358  GLU A CA    1 
ATOM   1940  C  C     . GLU A 1 340  ? 116.617 137.571 81.233  1.00 47.01  ? 358  GLU A C     1 
ATOM   1941  O  O     . GLU A 1 340  ? 116.762 137.823 80.033  1.00 47.01  ? 358  GLU A O     1 
ATOM   1942  C  CB    . GLU A 1 340  ? 117.364 139.296 82.896  1.00 47.01  ? 358  GLU A CB    1 
ATOM   1943  C  CG    . GLU A 1 340  ? 117.071 140.646 83.539  1.00 47.01  ? 358  GLU A CG    1 
ATOM   1944  C  CD    . GLU A 1 340  ? 116.211 140.550 84.788  1.00 47.01  ? 358  GLU A CD    1 
ATOM   1945  O  OE1   . GLU A 1 340  ? 115.799 139.430 85.157  1.00 47.01  ? 358  GLU A OE1   1 
ATOM   1946  O  OE2   . GLU A 1 340  ? 115.945 141.604 85.404  1.00 47.01  ? 358  GLU A OE2   1 
ATOM   1947  N  N     . VAL A 1 341  ? 116.845 136.357 81.736  1.00 44.06  ? 359  VAL A N     1 
ATOM   1948  C  CA    . VAL A 1 341  ? 117.248 135.258 80.862  1.00 44.06  ? 359  VAL A CA    1 
ATOM   1949  C  C     . VAL A 1 341  ? 116.136 134.934 79.870  1.00 44.06  ? 359  VAL A C     1 
ATOM   1950  O  O     . VAL A 1 341  ? 116.389 134.716 78.677  1.00 44.06  ? 359  VAL A O     1 
ATOM   1951  C  CB    . VAL A 1 341  ? 117.648 134.030 81.701  1.00 44.06  ? 359  VAL A CB    1 
ATOM   1952  C  CG1   . VAL A 1 341  ? 117.909 132.847 80.814  1.00 44.06  ? 359  VAL A CG1   1 
ATOM   1953  C  CG2   . VAL A 1 341  ? 118.892 134.329 82.512  1.00 44.06  ? 359  VAL A CG2   1 
ATOM   1954  N  N     . HIS A 1 342  ? 114.889 134.904 80.344  1.00 43.16  ? 360  HIS A N     1 
ATOM   1955  C  CA    . HIS A 1 342  ? 113.763 134.633 79.456  1.00 43.16  ? 360  HIS A CA    1 
ATOM   1956  C  C     . HIS A 1 342  ? 113.591 135.742 78.429  1.00 43.16  ? 360  HIS A C     1 
ATOM   1957  O  O     . HIS A 1 342  ? 113.251 135.476 77.271  1.00 43.16  ? 360  HIS A O     1 
ATOM   1958  C  CB    . HIS A 1 342  ? 112.483 134.454 80.269  1.00 43.16  ? 360  HIS A CB    1 
ATOM   1959  C  CG    . HIS A 1 342  ? 111.254 134.298 79.431  1.00 43.16  ? 360  HIS A CG    1 
ATOM   1960  N  ND1   . HIS A 1 342  ? 110.379 135.335 79.193  1.00 43.16  ? 360  HIS A ND1   1 
ATOM   1961  C  CD2   . HIS A 1 342  ? 110.755 133.227 78.772  1.00 43.16  ? 360  HIS A CD2   1 
ATOM   1962  C  CE1   . HIS A 1 342  ? 109.392 134.909 78.426  1.00 43.16  ? 360  HIS A CE1   1 
ATOM   1963  N  NE2   . HIS A 1 342  ? 109.597 133.633 78.156  1.00 43.16  ? 360  HIS A NE2   1 
ATOM   1964  N  N     . ARG A 1 343  ? 113.811 136.991 78.837  1.00 47.79  ? 361  ARG A N     1 
ATOM   1965  C  CA    . ARG A 1 343  ? 113.759 138.100 77.891  1.00 47.79  ? 361  ARG A CA    1 
ATOM   1966  C  C     . ARG A 1 343  ? 114.858 137.979 76.842  1.00 47.79  ? 361  ARG A C     1 
ATOM   1967  O  O     . ARG A 1 343  ? 114.640 138.284 75.663  1.00 47.79  ? 361  ARG A O     1 
ATOM   1968  C  CB    . ARG A 1 343  ? 113.868 139.426 78.644  1.00 47.79  ? 361  ARG A CB    1 
ATOM   1969  C  CG    . ARG A 1 343  ? 113.884 140.657 77.759  1.00 47.79  ? 361  ARG A CG    1 
ATOM   1970  C  CD    . ARG A 1 343  ? 113.988 141.920 78.595  1.00 47.79  ? 361  ARG A CD    1 
ATOM   1971  N  NE    . ARG A 1 343  ? 114.027 143.117 77.765  1.00 47.79  ? 361  ARG A NE    1 
ATOM   1972  C  CZ    . ARG A 1 343  ? 115.141 143.684 77.324  1.00 47.79  ? 361  ARG A CZ    1 
ATOM   1973  N  NH1   . ARG A 1 343  ? 116.332 143.190 77.621  1.00 47.79  ? 361  ARG A NH1   1 
ATOM   1974  N  NH2   . ARG A 1 343  ? 115.058 144.775 76.569  1.00 47.79  ? 361  ARG A NH2   1 
ATOM   1975  N  N     . LEU A 1 344  ? 116.048 137.535 77.252  1.00 43.51  ? 362  LEU A N     1 
ATOM   1976  C  CA    . LEU A 1 344  ? 117.164 137.414 76.319  1.00 43.51  ? 362  LEU A CA    1 
ATOM   1977  C  C     . LEU A 1 344  ? 116.924 136.301 75.307  1.00 43.51  ? 362  LEU A C     1 
ATOM   1978  O  O     . LEU A 1 344  ? 117.105 136.497 74.100  1.00 43.51  ? 362  LEU A O     1 
ATOM   1979  C  CB    . LEU A 1 344  ? 118.463 137.173 77.091  1.00 43.51  ? 362  LEU A CB    1 
ATOM   1980  C  CG    . LEU A 1 344  ? 119.801 137.278 76.350  1.00 43.51  ? 362  LEU A CG    1 
ATOM   1981  C  CD1   . LEU A 1 344  ? 120.171 135.980 75.641  1.00 43.51  ? 362  LEU A CD1   1 
ATOM   1982  C  CD2   . LEU A 1 344  ? 119.775 138.438 75.368  1.00 43.51  ? 362  LEU A CD2   1 
ATOM   1983  N  N     . TYR A 1 345  ? 116.521 135.121 75.775  1.00 40.88  ? 363  TYR A N     1 
ATOM   1984  C  CA    . TYR A 1 345  ? 116.408 133.970 74.884  1.00 40.88  ? 363  TYR A CA    1 
ATOM   1985  C  C     . TYR A 1 345  ? 115.052 133.912 74.186  1.00 40.88  ? 363  TYR A C     1 
ATOM   1986  O  O     . TYR A 1 345  ? 114.984 133.882 72.954  1.00 40.88  ? 363  TYR A O     1 
ATOM   1987  C  CB    . TYR A 1 345  ? 116.675 132.674 75.658  1.00 40.88  ? 363  TYR A CB    1 
ATOM   1988  C  CG    . TYR A 1 345  ? 118.129 132.487 76.025  1.00 40.88  ? 363  TYR A CG    1 
ATOM   1989  C  CD1   . TYR A 1 345  ? 118.640 133.007 77.205  1.00 40.88  ? 363  TYR A CD1   1 
ATOM   1990  C  CD2   . TYR A 1 345  ? 118.995 131.801 75.184  1.00 40.88  ? 363  TYR A CD2   1 
ATOM   1991  C  CE1   . TYR A 1 345  ? 119.968 132.845 77.541  1.00 40.88  ? 363  TYR A CE1   1 
ATOM   1992  C  CE2   . TYR A 1 345  ? 120.327 131.636 75.513  1.00 40.88  ? 363  TYR A CE2   1 
ATOM   1993  C  CZ    . TYR A 1 345  ? 120.805 132.160 76.693  1.00 40.88  ? 363  TYR A CZ    1 
ATOM   1994  O  OH    . TYR A 1 345  ? 122.128 131.998 77.027  1.00 40.88  ? 363  TYR A OH    1 
ATOM   1995  N  N     . VAL A 1 346  ? 113.969 133.902 74.955  1.00 45.50  ? 364  VAL A N     1 
ATOM   1996  C  CA    . VAL A 1 346  ? 112.638 133.737 74.377  1.00 45.50  ? 364  VAL A CA    1 
ATOM   1997  C  C     . VAL A 1 346  ? 112.037 135.074 73.967  1.00 45.50  ? 364  VAL A C     1 
ATOM   1998  O  O     . VAL A 1 346  ? 111.616 135.252 72.822  1.00 45.50  ? 364  VAL A O     1 
ATOM   1999  C  CB    . VAL A 1 346  ? 111.723 132.989 75.368  1.00 45.50  ? 364  VAL A CB    1 
ATOM   2000  C  CG1   . VAL A 1 346  ? 110.435 132.570 74.682  1.00 45.50  ? 364  VAL A CG1   1 
ATOM   2001  C  CG2   . VAL A 1 346  ? 112.449 131.787 75.943  1.00 45.50  ? 364  VAL A CG2   1 
ATOM   2002  N  N     . GLY A 1 347  ? 111.983 136.031 74.889  1.00 52.98  ? 365  GLY A N     1 
ATOM   2003  C  CA    . GLY A 1 347  ? 111.430 137.335 74.588  1.00 52.98  ? 365  GLY A CA    1 
ATOM   2004  C  C     . GLY A 1 347  ? 109.913 137.329 74.552  1.00 52.98  ? 365  GLY A C     1 
ATOM   2005  O  O     . GLY A 1 347  ? 109.249 136.301 74.700  1.00 52.98  ? 365  GLY A O     1 
ATOM   2006  N  N     . GLY A 1 348  ? 109.357 138.520 74.347  1.00 62.57  ? 366  GLY A N     1 
ATOM   2007  C  CA    . GLY A 1 348  ? 107.927 138.686 74.248  1.00 62.57  ? 366  GLY A CA    1 
ATOM   2008  C  C     . GLY A 1 348  ? 107.315 139.261 75.509  1.00 62.57  ? 366  GLY A C     1 
ATOM   2009  O  O     . GLY A 1 348  ? 107.818 140.228 76.089  1.00 62.57  ? 366  GLY A O     1 
ATOM   2010  N  N     . PRO A 1 349  ? 106.205 138.676 75.952  1.00 61.59  ? 367  PRO A N     1 
ATOM   2011  C  CA    . PRO A 1 349  ? 105.548 139.151 77.174  1.00 61.59  ? 367  PRO A CA    1 
ATOM   2012  C  C     . PRO A 1 349  ? 106.442 138.946 78.383  1.00 61.59  ? 367  PRO A C     1 
ATOM   2013  O  O     . PRO A 1 349  ? 106.789 137.805 78.724  1.00 61.59  ? 367  PRO A O     1 
ATOM   2014  C  CB    . PRO A 1 349  ? 104.285 138.280 77.258  1.00 61.59  ? 367  PRO A CB    1 
ATOM   2015  C  CG    . PRO A 1 349  ? 104.613 137.059 76.466  1.00 61.59  ? 367  PRO A CG    1 
ATOM   2016  C  CD    . PRO A 1 349  ? 105.499 137.532 75.351  1.00 61.59  ? 367  PRO A CD    1 
ATOM   2017  N  N     . PRO A 1 350  ? 106.838 140.024 79.053  1.00 62.26  ? 368  PRO A N     1 
ATOM   2018  C  CA    . PRO A 1 350  ? 107.770 139.891 80.176  1.00 62.26  ? 368  PRO A CA    1 
ATOM   2019  C  C     . PRO A 1 350  ? 107.149 139.147 81.347  1.00 62.26  ? 368  PRO A C     1 
ATOM   2020  O  O     . PRO A 1 350  ? 105.933 139.162 81.554  1.00 62.26  ? 368  PRO A O     1 
ATOM   2021  C  CB    . PRO A 1 350  ? 108.086 141.343 80.547  1.00 62.26  ? 368  PRO A CB    1 
ATOM   2022  C  CG    . PRO A 1 350  ? 106.886 142.103 80.103  1.00 62.26  ? 368  PRO A CG    1 
ATOM   2023  C  CD    . PRO A 1 350  ? 106.412 141.419 78.851  1.00 62.26  ? 368  PRO A CD    1 
ATOM   2024  N  N     . LEU A 1 351  ? 108.010 138.483 82.113  1.00 57.63  ? 369  LEU A N     1 
ATOM   2025  C  CA    . LEU A 1 351  ? 107.581 137.787 83.317  1.00 57.63  ? 369  LEU A CA    1 
ATOM   2026  C  C     . LEU A 1 351  ? 107.321 138.797 84.426  1.00 57.63  ? 369  LEU A C     1 
ATOM   2027  O  O     . LEU A 1 351  ? 108.155 139.668 84.693  1.00 57.63  ? 369  LEU A O     1 
ATOM   2028  C  CB    . LEU A 1 351  ? 108.639 136.774 83.755  1.00 57.63  ? 369  LEU A CB    1 
ATOM   2029  C  CG    . LEU A 1 351  ? 108.494 135.331 83.265  1.00 57.63  ? 369  LEU A CG    1 
ATOM   2030  C  CD1   . LEU A 1 351  ? 107.419 134.603 84.052  1.00 57.63  ? 369  LEU A CD1   1 
ATOM   2031  C  CD2   . LEU A 1 351  ? 108.188 135.280 81.776  1.00 57.63  ? 369  LEU A CD2   1 
ATOM   2032  N  N     . GLU A 1 352  ? 106.166 138.677 85.073  1.00 62.04  ? 370  GLU A N     1 
ATOM   2033  C  CA    . GLU A 1 352  ? 105.759 139.641 86.087  1.00 62.04  ? 370  GLU A CA    1 
ATOM   2034  C  C     . GLU A 1 352  ? 106.440 139.319 87.410  1.00 62.04  ? 370  GLU A C     1 
ATOM   2035  O  O     . GLU A 1 352  ? 106.171 138.277 88.017  1.00 62.04  ? 370  GLU A O     1 
ATOM   2036  C  CB    . GLU A 1 352  ? 104.240 139.635 86.252  1.00 62.04  ? 370  GLU A CB    1 
ATOM   2037  C  CG    . GLU A 1 352  ? 103.461 140.111 85.032  1.00 62.04  ? 370  GLU A CG    1 
ATOM   2038  C  CD    . GLU A 1 352  ? 103.278 139.027 83.986  1.00 62.04  ? 370  GLU A CD    1 
ATOM   2039  O  OE1   . GLU A 1 352  ? 103.838 137.924 84.161  1.00 62.04  ? 370  GLU A OE1   1 
ATOM   2040  O  OE2   . GLU A 1 352  ? 102.569 139.277 82.989  1.00 62.04  ? 370  GLU A OE2   1 
ATOM   2041  N  N     . LYS A 1 353  ? 107.326 140.207 87.853  1.00 66.62  ? 371  LYS A N     1 
ATOM   2042  C  CA    . LYS A 1 353  ? 107.895 140.097 89.189  1.00 66.62  ? 371  LYS A CA    1 
ATOM   2043  C  C     . LYS A 1 353  ? 106.846 140.513 90.210  1.00 66.62  ? 371  LYS A C     1 
ATOM   2044  O  O     . LYS A 1 353  ? 106.353 141.644 90.174  1.00 66.62  ? 371  LYS A O     1 
ATOM   2045  C  CB    . LYS A 1 353  ? 109.140 140.971 89.311  1.00 66.62  ? 371  LYS A CB    1 
ATOM   2046  C  CG    . LYS A 1 353  ? 110.302 140.535 88.438  1.00 66.62  ? 371  LYS A CG    1 
ATOM   2047  C  CD    . LYS A 1 353  ? 111.401 141.585 88.426  1.00 66.62  ? 371  LYS A CD    1 
ATOM   2048  C  CE    . LYS A 1 353  ? 111.806 141.984 89.837  1.00 66.62  ? 371  LYS A CE    1 
ATOM   2049  N  NZ    . LYS A 1 353  ? 112.301 140.825 90.628  1.00 66.62  ? 371  LYS A NZ    1 
ATOM   2050  N  N     . GLU A 1 354  ? 106.501 139.608 91.111  1.00 64.94  ? 372  GLU A N     1 
ATOM   2051  C  CA    . GLU A 1 354  ? 105.448 139.896 92.075  1.00 64.94  ? 372  GLU A CA    1 
ATOM   2052  C  C     . GLU A 1 354  ? 105.940 140.894 93.114  1.00 64.94  ? 372  GLU A C     1 
ATOM   2053  O  O     . GLU A 1 354  ? 106.926 140.615 93.809  1.00 64.94  ? 372  GLU A O     1 
ATOM   2054  C  CB    . GLU A 1 354  ? 104.984 138.611 92.753  1.00 64.94  ? 372  GLU A CB    1 
ATOM   2055  C  CG    . GLU A 1 354  ? 103.881 138.819 93.775  1.00 64.94  ? 372  GLU A CG    1 
ATOM   2056  C  CD    . GLU A 1 354  ? 103.206 137.522 94.173  1.00 64.94  ? 372  GLU A CD    1 
ATOM   2057  O  OE1   . GLU A 1 354  ? 103.523 136.475 93.569  1.00 64.94  ? 372  GLU A OE1   1 
ATOM   2058  O  OE2   . GLU A 1 354  ? 102.357 137.549 95.087  1.00 64.94  ? 372  GLU A OE2   1 
ATOM   2059  N  N     . PRO A 1 355  ? 105.298 142.058 93.257  1.00 62.94  ? 373  PRO A N     1 
ATOM   2060  C  CA    . PRO A 1 355  ? 105.658 142.970 94.349  1.00 62.94  ? 373  PRO A CA    1 
ATOM   2061  C  C     . PRO A 1 355  ? 105.106 142.539 95.694  1.00 62.94  ? 373  PRO A C     1 
ATOM   2062  O  O     . PRO A 1 355  ? 105.593 143.014 96.729  1.00 62.94  ? 373  PRO A O     1 
ATOM   2063  C  CB    . PRO A 1 355  ? 105.039 144.299 93.903  1.00 62.94  ? 373  PRO A CB    1 
ATOM   2064  C  CG    . PRO A 1 355  ? 103.845 143.885 93.111  1.00 62.94  ? 373  PRO A CG    1 
ATOM   2065  C  CD    . PRO A 1 355  ? 104.229 142.608 92.405  1.00 62.94  ? 373  PRO A CD    1 
ATOM   2066  N  N     . ARG A 1 356  ? 104.106 141.660 95.705  1.00 68.35  ? 374  ARG A N     1 
ATOM   2067  C  CA    . ARG A 1 356  ? 103.552 141.105 96.939  1.00 68.35  ? 374  ARG A CA    1 
ATOM   2068  C  C     . ARG A 1 356  ? 104.396 139.900 97.356  1.00 68.35  ? 374  ARG A C     1 
ATOM   2069  O  O     . ARG A 1 356  ? 104.030 138.737 97.176  1.00 68.35  ? 374  ARG A O     1 
ATOM   2070  C  CB    . ARG A 1 356  ? 102.088 140.738 96.737  1.00 68.35  ? 374  ARG A CB    1 
ATOM   2071  C  CG    . ARG A 1 356  ? 101.332 140.391 98.004  1.00 68.35  ? 374  ARG A CG    1 
ATOM   2072  C  CD    . ARG A 1 356  ? 99.879  140.072 97.689  1.00 68.35  ? 374  ARG A CD    1 
ATOM   2073  N  NE    . ARG A 1 356  ? 99.765  139.054 96.650  1.00 68.35  ? 374  ARG A NE    1 
ATOM   2074  C  CZ    . ARG A 1 356  ? 98.623  138.673 96.096  1.00 68.35  ? 374  ARG A CZ    1 
ATOM   2075  N  NH1   . ARG A 1 356  ? 97.466  139.201 96.462  1.00 68.35  ? 374  ARG A NH1   1 
ATOM   2076  N  NH2   . ARG A 1 356  ? 98.641  137.740 95.148  1.00 68.35  ? 374  ARG A NH2   1 
ATOM   2077  N  N     . GLU A 1 357  ? 105.563 140.209 97.925  1.00 61.77  ? 375  GLU A N     1 
ATOM   2078  C  CA    . GLU A 1 357  ? 106.572 139.201 98.252  1.00 61.77  ? 375  GLU A CA    1 
ATOM   2079  C  C     . GLU A 1 357  ? 106.115 138.414 99.476  1.00 61.77  ? 375  GLU A C     1 
ATOM   2080  O  O     . GLU A 1 357  ? 106.533 138.654 100.610 1.00 61.77  ? 375  GLU A O     1 
ATOM   2081  C  CB    . GLU A 1 357  ? 107.927 139.857 98.487  1.00 61.77  ? 375  GLU A CB    1 
ATOM   2082  C  CG    . GLU A 1 357  ? 108.451 140.632 97.293  1.00 61.77  ? 375  GLU A CG    1 
ATOM   2083  C  CD    . GLU A 1 357  ? 109.797 141.272 97.560  1.00 61.77  ? 375  GLU A CD    1 
ATOM   2084  O  OE1   . GLU A 1 357  ? 110.350 141.060 98.660  1.00 61.77  ? 375  GLU A OE1   1 
ATOM   2085  O  OE2   . GLU A 1 357  ? 110.302 141.988 96.671  1.00 61.77  ? 375  GLU A OE2   1 
ATOM   2086  N  N     . LEU A 1 358  ? 105.233 137.447 99.231  1.00 55.67  ? 376  LEU A N     1 
ATOM   2087  C  CA    . LEU A 1 358  ? 104.688 136.600 100.282 1.00 55.67  ? 376  LEU A CA    1 
ATOM   2088  C  C     . LEU A 1 358  ? 105.551 135.374 100.556 1.00 55.67  ? 376  LEU A C     1 
ATOM   2089  O  O     . LEU A 1 358  ? 105.067 134.406 101.154 1.00 55.67  ? 376  LEU A O     1 
ATOM   2090  C  CB    . LEU A 1 358  ? 103.262 136.178 99.922  1.00 55.67  ? 376  LEU A CB    1 
ATOM   2091  C  CG    . LEU A 1 358  ? 102.309 137.348 99.668  1.00 55.67  ? 376  LEU A CG    1 
ATOM   2092  C  CD1   . LEU A 1 358  ? 100.935 136.861 99.242  1.00 55.67  ? 376  LEU A CD1   1 
ATOM   2093  C  CD2   . LEU A 1 358  ? 102.210 138.235 100.898 1.00 55.67  ? 376  LEU A CD2   1 
ATOM   2094  N  N     . PHE A 1 359  ? 106.816 135.397 100.133 1.00 46.25  ? 377  PHE A N     1 
ATOM   2095  C  CA    . PHE A 1 359  ? 107.755 134.312 100.399 1.00 46.25  ? 377  PHE A CA    1 
ATOM   2096  C  C     . PHE A 1 359  ? 109.078 134.772 100.989 1.00 46.25  ? 377  PHE A C     1 
ATOM   2097  O  O     . PHE A 1 359  ? 109.813 133.934 101.523 1.00 46.25  ? 377  PHE A O     1 
ATOM   2098  C  CB    . PHE A 1 359  ? 108.037 133.517 99.116  1.00 46.25  ? 377  PHE A CB    1 
ATOM   2099  C  CG    . PHE A 1 359  ? 107.009 132.470 98.818  1.00 46.25  ? 377  PHE A CG    1 
ATOM   2100  C  CD1   . PHE A 1 359  ? 106.584 131.602 99.806  1.00 46.25  ? 377  PHE A CD1   1 
ATOM   2101  C  CD2   . PHE A 1 359  ? 106.461 132.357 97.556  1.00 46.25  ? 377  PHE A CD2   1 
ATOM   2102  C  CE1   . PHE A 1 359  ? 105.639 130.635 99.537  1.00 46.25  ? 377  PHE A CE1   1 
ATOM   2103  C  CE2   . PHE A 1 359  ? 105.513 131.394 97.282  1.00 46.25  ? 377  PHE A CE2   1 
ATOM   2104  C  CZ    . PHE A 1 359  ? 105.101 130.532 98.275  1.00 46.25  ? 377  PHE A CZ    1 
ATOM   2105  N  N     . VAL A 1 360  ? 109.409 136.059 100.912 1.00 52.67  ? 378  VAL A N     1 
ATOM   2106  C  CA    . VAL A 1 360  ? 110.605 136.604 101.540 1.00 52.67  ? 378  VAL A CA    1 
ATOM   2107  C  C     . VAL A 1 360  ? 110.278 137.423 102.774 1.00 52.67  ? 378  VAL A C     1 
ATOM   2108  O  O     . VAL A 1 360  ? 111.105 137.499 103.695 1.00 52.67  ? 378  VAL A O     1 
ATOM   2109  C  CB    . VAL A 1 360  ? 111.420 137.448 100.542 1.00 52.67  ? 378  VAL A CB    1 
ATOM   2110  C  CG1   . VAL A 1 360  ? 112.834 137.665 101.055 1.00 52.67  ? 378  VAL A CG1   1 
ATOM   2111  C  CG2   . VAL A 1 360  ? 111.429 136.785 99.174  1.00 52.67  ? 378  VAL A CG2   1 
ATOM   2112  N  N     . LYS A 1 361  ? 109.097 138.037 102.826 1.00 52.64  ? 379  LYS A N     1 
ATOM   2113  C  CA    . LYS A 1 361  ? 108.677 138.827 103.975 1.00 52.64  ? 379  LYS A CA    1 
ATOM   2114  C  C     . LYS A 1 361  ? 107.212 138.567 104.306 1.00 52.64  ? 379  LYS A C     1 
ATOM   2115  O  O     . LYS A 1 361  ? 106.454 139.506 104.567 1.00 52.64  ? 379  LYS A O     1 
ATOM   2116  C  CB    . LYS A 1 361  ? 108.918 140.311 103.704 1.00 52.64  ? 379  LYS A CB    1 
ATOM   2117  C  CG    . LYS A 1 361  ? 108.521 140.752 102.308 1.00 52.64  ? 379  LYS A CG    1 
ATOM   2118  C  CD    . LYS A 1 361  ? 109.057 142.137 102.005 1.00 52.64  ? 379  LYS A CD    1 
ATOM   2119  C  CE    . LYS A 1 361  ? 110.566 142.179 102.164 1.00 52.64  ? 379  LYS A CE    1 
ATOM   2120  N  NZ    . LYS A 1 361  ? 111.232 141.162 101.306 1.00 52.64  ? 379  LYS A NZ    1 
ATOM   2121  N  N     . GLY A 1 362  ? 106.801 137.298 104.291 1.00 49.11  ? 380  GLY A N     1 
ATOM   2122  C  CA    . GLY A 1 362  ? 105.425 136.935 104.556 1.00 49.11  ? 380  GLY A CA    1 
ATOM   2123  C  C     . GLY A 1 362  ? 105.337 135.828 105.587 1.00 49.11  ? 380  GLY A C     1 
ATOM   2124  O  O     . GLY A 1 362  ? 106.349 135.307 106.055 1.00 49.11  ? 380  GLY A O     1 
ATOM   2125  N  N     . THR A 1 363  ? 104.103 135.479 105.929 1.00 54.36  ? 381  THR A N     1 
ATOM   2126  C  CA    . THR A 1 363  ? 103.808 134.480 106.946 1.00 54.36  ? 381  THR A CA    1 
ATOM   2127  C  C     . THR A 1 363  ? 103.038 133.320 106.321 1.00 54.36  ? 381  THR A C     1 
ATOM   2128  O  O     . THR A 1 363  ? 102.799 133.281 105.112 1.00 54.36  ? 381  THR A O     1 
ATOM   2129  C  CB    . THR A 1 363  ? 103.016 135.096 108.103 1.00 54.36  ? 381  THR A CB    1 
ATOM   2130  O  OG1   . THR A 1 363  ? 101.697 135.432 107.655 1.00 54.36  ? 381  THR A OG1   1 
ATOM   2131  C  CG2   . THR A 1 363  ? 103.703 136.355 108.604 1.00 54.36  ? 381  THR A CG2   1 
ATOM   2132  N  N     . MET A 1 364  ? 102.659 132.359 107.166 1.00 59.08  ? 382  MET A N     1 
ATOM   2133  C  CA    . MET A 1 364  ? 101.893 131.214 106.685 1.00 59.08  ? 382  MET A CA    1 
ATOM   2134  C  C     . MET A 1 364  ? 100.524 131.640 106.171 1.00 59.08  ? 382  MET A C     1 
ATOM   2135  O  O     . MET A 1 364  ? 100.049 131.128 105.151 1.00 59.08  ? 382  MET A O     1 
ATOM   2136  C  CB    . MET A 1 364  ? 101.755 130.175 107.799 1.00 59.08  ? 382  MET A CB    1 
ATOM   2137  C  CG    . MET A 1 364  ? 101.250 128.809 107.344 1.00 59.08  ? 382  MET A CG    1 
ATOM   2138  S  SD    . MET A 1 364  ? 99.461  128.701 107.137 1.00 59.08  ? 382  MET A SD    1 
ATOM   2139  C  CE    . MET A 1 364  ? 98.904  129.098 108.791 1.00 59.08  ? 382  MET A CE    1 
ATOM   2140  N  N     . LYS A 1 365  ? 99.870  132.573 106.867 1.00 61.77  ? 383  LYS A N     1 
ATOM   2141  C  CA    . LYS A 1 365  ? 98.527  132.994 106.480 1.00 61.77  ? 383  LYS A CA    1 
ATOM   2142  C  C     . LYS A 1 365  ? 98.538  133.754 105.159 1.00 61.77  ? 383  LYS A C     1 
ATOM   2143  O  O     . LYS A 1 365  ? 97.628  133.598 104.336 1.00 61.77  ? 383  LYS A O     1 
ATOM   2144  C  CB    . LYS A 1 365  ? 97.908  133.848 107.589 1.00 61.77  ? 383  LYS A CB    1 
ATOM   2145  C  CG    . LYS A 1 365  ? 96.455  134.229 107.349 1.00 61.77  ? 383  LYS A CG    1 
ATOM   2146  C  CD    . LYS A 1 365  ? 95.880  134.996 108.530 1.00 61.77  ? 383  LYS A CD    1 
ATOM   2147  C  CE    . LYS A 1 365  ? 94.434  135.388 108.280 1.00 61.77  ? 383  LYS A CE    1 
ATOM   2148  N  NZ    . LYS A 1 365  ? 94.298  136.268 107.087 1.00 61.77  ? 383  LYS A NZ    1 
ATOM   2149  N  N     . ASP A 1 366  ? 99.571  134.564 104.938 1.00 60.71  ? 384  ASP A N     1 
ATOM   2150  C  CA    . ASP A 1 366  ? 99.686  135.330 103.693 1.00 60.71  ? 384  ASP A CA    1 
ATOM   2151  C  C     . ASP A 1 366  ? 99.735  134.418 102.479 1.00 60.71  ? 384  ASP A C     1 
ATOM   2152  O  O     . ASP A 1 366  ? 99.357  134.821 101.383 1.00 60.71  ? 384  ASP A O     1 
ATOM   2153  C  CB    . ASP A 1 366  ? 100.940 136.199 103.723 1.00 60.71  ? 384  ASP A CB    1 
ATOM   2154  C  CG    . ASP A 1 366  ? 101.139 136.888 105.051 1.00 60.71  ? 384  ASP A CG    1 
ATOM   2155  O  OD1   . ASP A 1 366  ? 100.217 136.844 105.891 1.00 60.71  ? 384  ASP A OD1   1 
ATOM   2156  O  OD2   . ASP A 1 366  ? 102.221 137.474 105.258 1.00 60.71  ? 384  ASP A OD2   1 
ATOM   2157  N  N     . ILE A 1 367  ? 100.199 133.193 102.663 1.00 58.31  ? 385  ILE A N     1 
ATOM   2158  C  CA    . ILE A 1 367  ? 100.306 132.232 101.575 1.00 58.31  ? 385  ILE A CA    1 
ATOM   2159  C  C     . ILE A 1 367  ? 99.026  131.411 101.523 1.00 58.31  ? 385  ILE A C     1 
ATOM   2160  O  O     . ILE A 1 367  ? 98.484  131.142 100.444 1.00 58.31  ? 385  ILE A O     1 
ATOM   2161  C  CB    . ILE A 1 367  ? 101.542 131.335 101.760 1.00 58.31  ? 385  ILE A CB    1 
ATOM   2162  C  CG1   . ILE A 1 367  ? 102.795 132.201 101.897 1.00 58.31  ? 385  ILE A CG1   1 
ATOM   2163  C  CG2   . ILE A 1 367  ? 101.677 130.360 100.603 1.00 58.31  ? 385  ILE A CG2   1 
ATOM   2164  C  CD1   . ILE A 1 367  ? 103.975 131.473 102.488 1.00 58.31  ? 385  ILE A CD1   1 
ATOM   2165  N  N     . ARG A 1 368  ? 98.528  131.015 102.696 1.00 63.42  ? 386  ARG A N     1 
ATOM   2166  C  CA    . ARG A 1 368  ? 97.309  130.216 102.740 1.00 63.42  ? 386  ARG A CA    1 
ATOM   2167  C  C     . ARG A 1 368  ? 96.131  130.979 102.150 1.00 63.42  ? 386  ARG A C     1 
ATOM   2168  O  O     . ARG A 1 368  ? 95.162  130.365 101.689 1.00 63.42  ? 386  ARG A O     1 
ATOM   2169  C  CB    . ARG A 1 368  ? 97.023  129.784 104.181 1.00 63.42  ? 386  ARG A CB    1 
ATOM   2170  C  CG    . ARG A 1 368  ? 96.016  128.649 104.322 1.00 63.42  ? 386  ARG A CG    1 
ATOM   2171  C  CD    . ARG A 1 368  ? 94.611  129.179 104.566 1.00 63.42  ? 386  ARG A CD    1 
ATOM   2172  N  NE    . ARG A 1 368  ? 94.537  129.961 105.794 1.00 63.42  ? 386  ARG A NE    1 
ATOM   2173  C  CZ    . ARG A 1 368  ? 93.516  130.737 106.129 1.00 63.42  ? 386  ARG A CZ    1 
ATOM   2174  N  NH1   . ARG A 1 368  ? 92.461  130.870 105.341 1.00 63.42  ? 386  ARG A NH1   1 
ATOM   2175  N  NH2   . ARG A 1 368  ? 93.555  131.398 107.282 1.00 63.42  ? 386  ARG A NH2   1 
ATOM   2176  N  N     . GLU A 1 369  ? 96.202  132.309 102.135 1.00 67.59  ? 387  GLU A N     1 
ATOM   2177  C  CA    . GLU A 1 369  ? 95.178  133.117 101.486 1.00 67.59  ? 387  GLU A CA    1 
ATOM   2178  C  C     . GLU A 1 369  ? 95.424  133.287 99.989  1.00 67.59  ? 387  GLU A C     1 
ATOM   2179  O  O     . GLU A 1 369  ? 94.560  132.926 99.184  1.00 67.59  ? 387  GLU A O     1 
ATOM   2180  C  CB    . GLU A 1 369  ? 95.073  134.486 102.167 1.00 67.59  ? 387  GLU A CB    1 
ATOM   2181  C  CG    . GLU A 1 369  ? 94.626  134.407 103.617 1.00 67.59  ? 387  GLU A CG    1 
ATOM   2182  C  CD    . GLU A 1 369  ? 93.563  135.429 103.959 1.00 67.59  ? 387  GLU A CD    1 
ATOM   2183  O  OE1   . GLU A 1 369  ? 93.145  136.181 103.054 1.00 67.59  ? 387  GLU A OE1   1 
ATOM   2184  O  OE2   . GLU A 1 369  ? 93.143  135.478 105.134 1.00 67.59  ? 387  GLU A OE2   1 
ATOM   2185  N  N     . ASN A 1 370  ? 96.581  133.828 99.589  1.00 62.07  ? 388  ASN A N     1 
ATOM   2186  C  CA    . ASN A 1 370  ? 96.880  133.993 98.164  1.00 62.07  ? 388  ASN A CA    1 
ATOM   2187  C  C     . ASN A 1 370  ? 97.593  132.782 97.566  1.00 62.07  ? 388  ASN A C     1 
ATOM   2188  O  O     . ASN A 1 370  ? 98.539  132.918 96.781  1.00 62.07  ? 388  ASN A O     1 
ATOM   2189  C  CB    . ASN A 1 370  ? 97.713  135.259 97.983  1.00 62.07  ? 388  ASN A CB    1 
ATOM   2190  C  CG    . ASN A 1 370  ? 97.260  136.387 98.889  1.00 62.07  ? 388  ASN A CG    1 
ATOM   2191  O  OD1   . ASN A 1 370  ? 96.428  137.208 98.507  1.00 62.07  ? 388  ASN A OD1   1 
ATOM   2192  N  ND2   . ASN A 1 370  ? 97.803  136.430 100.100 1.00 62.07  ? 388  ASN A ND2   1 
ATOM   2193  N  N     . PHE A 1 371  ? 97.109  131.589 97.912  1.00 57.53  ? 389  PHE A N     1 
ATOM   2194  C  CA    . PHE A 1 371  ? 97.595  130.343 97.327  1.00 57.53  ? 389  PHE A CA    1 
ATOM   2195  C  C     . PHE A 1 371  ? 97.427  130.319 95.813  1.00 57.53  ? 389  PHE A C     1 
ATOM   2196  O  O     . PHE A 1 371  ? 98.376  130.015 95.078  1.00 57.53  ? 389  PHE A O     1 
ATOM   2197  C  CB    . PHE A 1 371  ? 96.855  129.178 97.988  1.00 57.53  ? 389  PHE A CB    1 
ATOM   2198  C  CG    . PHE A 1 371  ? 97.102  127.844 97.352  1.00 57.53  ? 389  PHE A CG    1 
ATOM   2199  C  CD1   . PHE A 1 371  ? 98.320  127.205 97.499  1.00 57.53  ? 389  PHE A CD1   1 
ATOM   2200  C  CD2   . PHE A 1 371  ? 96.097  127.208 96.646  1.00 57.53  ? 389  PHE A CD2   1 
ATOM   2201  C  CE1   . PHE A 1 371  ? 98.539  125.968 96.928  1.00 57.53  ? 389  PHE A CE1   1 
ATOM   2202  C  CE2   . PHE A 1 371  ? 96.310  125.972 96.075  1.00 57.53  ? 389  PHE A CE2   1 
ATOM   2203  C  CZ    . PHE A 1 371  ? 97.531  125.351 96.217  1.00 57.53  ? 389  PHE A CZ    1 
ATOM   2204  N  N     . GLN A 1 372  ? 96.225  130.632 95.326  1.00 53.59  ? 390  GLN A N     1 
ATOM   2205  C  CA    . GLN A 1 372  ? 95.928  130.503 93.906  1.00 53.59  ? 390  GLN A CA    1 
ATOM   2206  C  C     . GLN A 1 372  ? 96.632  131.547 93.051  1.00 53.59  ? 390  GLN A C     1 
ATOM   2207  O  O     . GLN A 1 372  ? 96.647  131.404 91.824  1.00 53.59  ? 390  GLN A O     1 
ATOM   2208  C  CB    . GLN A 1 372  ? 94.418  130.582 93.679  1.00 53.59  ? 390  GLN A CB    1 
ATOM   2209  C  CG    . GLN A 1 372  ? 93.607  129.607 94.524  1.00 53.59  ? 390  GLN A CG    1 
ATOM   2210  C  CD    . GLN A 1 372  ? 93.806  128.159 94.115  1.00 53.59  ? 390  GLN A CD    1 
ATOM   2211  O  OE1   . GLN A 1 372  ? 94.371  127.871 93.061  1.00 53.59  ? 390  GLN A OE1   1 
ATOM   2212  N  NE2   . GLN A 1 372  ? 93.336  127.239 94.949  1.00 53.59  ? 390  GLN A NE2   1 
ATOM   2213  N  N     . ASP A 1 373  ? 97.208  132.583 93.654  1.00 58.48  ? 391  ASP A N     1 
ATOM   2214  C  CA    . ASP A 1 373  ? 97.993  133.559 92.910  1.00 58.48  ? 391  ASP A CA    1 
ATOM   2215  C  C     . ASP A 1 373  ? 99.488  133.315 93.020  1.00 58.48  ? 391  ASP A C     1 
ATOM   2216  O  O     . ASP A 1 373  ? 100.213 133.492 92.031  1.00 58.48  ? 391  ASP A O     1 
ATOM   2217  C  CB    . ASP A 1 373  ? 97.676  134.978 93.394  1.00 58.48  ? 391  ASP A CB    1 
ATOM   2218  C  CG    . ASP A 1 373  ? 98.185  136.048 92.444  1.00 58.48  ? 391  ASP A CG    1 
ATOM   2219  O  OD1   . ASP A 1 373  ? 98.614  135.700 91.323  1.00 58.48  ? 391  ASP A OD1   1 
ATOM   2220  O  OD2   . ASP A 1 373  ? 98.154  137.239 92.819  1.00 58.48  ? 391  ASP A OD2   1 
ATOM   2221  N  N     . LEU A 1 374  ? 99.966  132.890 94.193  1.00 53.53  ? 392  LEU A N     1 
ATOM   2222  C  CA    . LEU A 1 374  ? 101.363 132.494 94.301  1.00 53.53  ? 392  LEU A CA    1 
ATOM   2223  C  C     . LEU A 1 374  ? 101.655 131.287 93.420  1.00 53.53  ? 392  LEU A C     1 
ATOM   2224  O  O     . LEU A 1 374  ? 102.720 131.206 92.795  1.00 53.53  ? 392  LEU A O     1 
ATOM   2225  C  CB    . LEU A 1 374  ? 101.716 132.210 95.760  1.00 53.53  ? 392  LEU A CB    1 
ATOM   2226  C  CG    . LEU A 1 374  ? 101.700 133.434 96.677  1.00 53.53  ? 392  LEU A CG    1 
ATOM   2227  C  CD1   . LEU A 1 374  ? 101.958 133.027 98.113  1.00 53.53  ? 392  LEU A CD1   1 
ATOM   2228  C  CD2   . LEU A 1 374  ? 102.721 134.460 96.220  1.00 53.53  ? 392  LEU A CD2   1 
ATOM   2229  N  N     . MET A 1 375  ? 100.727 130.343 93.320  1.00 48.16  ? 393  MET A N     1 
ATOM   2230  C  CA    . MET A 1 375  ? 100.931 129.217 92.412  1.00 48.16  ? 393  MET A CA    1 
ATOM   2231  C  C     . MET A 1 375  ? 100.919 129.663 90.961  1.00 48.16  ? 393  MET A C     1 
ATOM   2232  O  O     . MET A 1 375  ? 101.672 129.139 90.154  1.00 48.16  ? 393  MET A O     1 
ATOM   2233  C  CB    . MET A 1 375  ? 99.890  128.126 92.626  1.00 48.16  ? 393  MET A CB    1 
ATOM   2234  C  CG    . MET A 1 375  ? 100.238 127.178 93.759  1.00 48.16  ? 393  MET A CG    1 
ATOM   2235  S  SD    . MET A 1 375  ? 99.798  125.472 93.380  1.00 48.16  ? 393  MET A SD    1 
ATOM   2236  C  CE    . MET A 1 375  ? 100.743 124.586 94.613  1.00 48.16  ? 393  MET A CE    1 
ATOM   2237  N  N     . GLN A 1 376  ? 100.080 130.629 90.614  1.00 52.30  ? 394  GLN A N     1 
ATOM   2238  C  CA    . GLN A 1 376  ? 100.121 131.137 89.244  1.00 52.30  ? 394  GLN A CA    1 
ATOM   2239  C  C     . GLN A 1 376  ? 101.470 131.773 88.929  1.00 52.30  ? 394  GLN A C     1 
ATOM   2240  O  O     . GLN A 1 376  ? 102.021 131.573 87.839  1.00 52.30  ? 394  GLN A O     1 
ATOM   2241  C  CB    . GLN A 1 376  ? 98.989  132.139 89.017  1.00 52.30  ? 394  GLN A CB    1 
ATOM   2242  C  CG    . GLN A 1 376  ? 97.717  131.519 88.467  1.00 52.30  ? 394  GLN A CG    1 
ATOM   2243  C  CD    . GLN A 1 376  ? 97.869  131.065 87.029  1.00 52.30  ? 394  GLN A CD    1 
ATOM   2244  O  OE1   . GLN A 1 376  ? 98.742  131.543 86.305  1.00 52.30  ? 394  GLN A OE1   1 
ATOM   2245  N  NE2   . GLN A 1 376  ? 97.019  130.136 86.608  1.00 52.30  ? 394  GLN A NE2   1 
ATOM   2246  N  N     . TYR A 1 377  ? 102.014 132.549 89.869  1.00 54.05  ? 395  TYR A N     1 
ATOM   2247  C  CA    . TYR A 1 377  ? 103.335 133.134 89.649  1.00 54.05  ? 395  TYR A CA    1 
ATOM   2248  C  C     . TYR A 1 377  ? 104.406 132.055 89.527  1.00 54.05  ? 395  TYR A C     1 
ATOM   2249  O  O     . TYR A 1 377  ? 105.292 132.137 88.664  1.00 54.05  ? 395  TYR A O     1 
ATOM   2250  C  CB    . TYR A 1 377  ? 103.676 134.111 90.773  1.00 54.05  ? 395  TYR A CB    1 
ATOM   2251  C  CG    . TYR A 1 377  ? 103.204 135.521 90.505  1.00 54.05  ? 395  TYR A CG    1 
ATOM   2252  C  CD1   . TYR A 1 377  ? 101.915 135.918 90.833  1.00 54.05  ? 395  TYR A CD1   1 
ATOM   2253  C  CD2   . TYR A 1 377  ? 104.046 136.455 89.918  1.00 54.05  ? 395  TYR A CD2   1 
ATOM   2254  C  CE1   . TYR A 1 377  ? 101.480 137.205 90.586  1.00 54.05  ? 395  TYR A CE1   1 
ATOM   2255  C  CE2   . TYR A 1 377  ? 103.620 137.743 89.667  1.00 54.05  ? 395  TYR A CE2   1 
ATOM   2256  C  CZ    . TYR A 1 377  ? 102.337 138.113 90.004  1.00 54.05  ? 395  TYR A CZ    1 
ATOM   2257  O  OH    . TYR A 1 377  ? 101.910 139.396 89.756  1.00 54.05  ? 395  TYR A OH    1 
ATOM   2258  N  N     . CYS A 1 378  ? 104.335 131.024 90.371  1.00 48.28  ? 396  CYS A N     1 
ATOM   2259  C  CA    . CYS A 1 378  ? 105.291 129.926 90.266  1.00 48.28  ? 396  CYS A CA    1 
ATOM   2260  C  C     . CYS A 1 378  ? 105.151 129.202 88.933  1.00 48.28  ? 396  CYS A C     1 
ATOM   2261  O  O     . CYS A 1 378  ? 106.152 128.821 88.314  1.00 48.28  ? 396  CYS A O     1 
ATOM   2262  C  CB    . CYS A 1 378  ? 105.105 128.953 91.428  1.00 48.28  ? 396  CYS A CB    1 
ATOM   2263  S  SG    . CYS A 1 378  ? 106.359 127.658 91.516  1.00 48.28  ? 396  CYS A SG    1 
ATOM   2264  N  N     . ALA A 1 379  ? 103.913 129.001 88.478  1.00 43.74  ? 397  ALA A N     1 
ATOM   2265  C  CA    . ALA A 1 379  ? 103.681 128.327 87.208  1.00 43.74  ? 397  ALA A CA    1 
ATOM   2266  C  C     . ALA A 1 379  ? 104.246 129.127 86.046  1.00 43.74  ? 397  ALA A C     1 
ATOM   2267  O  O     . ALA A 1 379  ? 104.830 128.555 85.119  1.00 43.74  ? 397  ALA A O     1 
ATOM   2268  C  CB    . ALA A 1 379  ? 102.186 128.081 87.015  1.00 43.74  ? 397  ALA A CB    1 
ATOM   2269  N  N     . GLN A 1 380  ? 104.086 130.451 86.070  1.00 46.41  ? 398  GLN A N     1 
ATOM   2270  C  CA    . GLN A 1 380  ? 104.657 131.247 84.988  1.00 46.41  ? 398  GLN A CA    1 
ATOM   2271  C  C     . GLN A 1 380  ? 106.181 131.264 85.054  1.00 46.41  ? 398  GLN A C     1 
ATOM   2272  O  O     . GLN A 1 380  ? 106.842 131.299 84.009  1.00 46.41  ? 398  GLN A O     1 
ATOM   2273  C  CB    . GLN A 1 380  ? 104.086 132.668 84.997  1.00 46.41  ? 398  GLN A CB    1 
ATOM   2274  C  CG    . GLN A 1 380  ? 104.637 133.595 86.061  1.00 46.41  ? 398  GLN A CG    1 
ATOM   2275  C  CD    . GLN A 1 380  ? 104.211 135.033 85.851  1.00 46.41  ? 398  GLN A CD    1 
ATOM   2276  O  OE1   . GLN A 1 380  ? 103.211 135.305 85.187  1.00 46.41  ? 398  GLN A OE1   1 
ATOM   2277  N  NE2   . GLN A 1 380  ? 104.975 135.964 86.410  1.00 46.41  ? 398  GLN A NE2   1 
ATOM   2278  N  N     . ASP A 1 381  ? 106.759 131.208 86.260  1.00 45.95  ? 399  ASP A N     1 
ATOM   2279  C  CA    . ASP A 1 381  ? 108.210 131.062 86.363  1.00 45.95  ? 399  ASP A CA    1 
ATOM   2280  C  C     . ASP A 1 381  ? 108.675 129.747 85.746  1.00 45.95  ? 399  ASP A C     1 
ATOM   2281  O  O     . ASP A 1 381  ? 109.672 129.711 85.012  1.00 45.95  ? 399  ASP A O     1 
ATOM   2282  C  CB    . ASP A 1 381  ? 108.648 131.145 87.824  1.00 45.95  ? 399  ASP A CB    1 
ATOM   2283  C  CG    . ASP A 1 381  ? 108.446 132.522 88.416  1.00 45.95  ? 399  ASP A CG    1 
ATOM   2284  O  OD1   . ASP A 1 381  ? 108.441 133.505 87.646  1.00 45.95  ? 399  ASP A OD1   1 
ATOM   2285  O  OD2   . ASP A 1 381  ? 108.296 132.623 89.652  1.00 45.95  ? 399  ASP A OD2   1 
ATOM   2286  N  N     . VAL A 1 382  ? 107.961 128.658 86.033  1.00 37.35  ? 400  VAL A N     1 
ATOM   2287  C  CA    . VAL A 1 382  ? 108.300 127.359 85.457  1.00 37.35  ? 400  VAL A CA    1 
ATOM   2288  C  C     . VAL A 1 382  ? 108.170 127.396 83.940  1.00 37.35  ? 400  VAL A C     1 
ATOM   2289  O  O     . VAL A 1 382  ? 108.991 126.821 83.215  1.00 37.35  ? 400  VAL A O     1 
ATOM   2290  C  CB    . VAL A 1 382  ? 107.418 126.257 86.073  1.00 37.35  ? 400  VAL A CB    1 
ATOM   2291  C  CG1   . VAL A 1 382  ? 107.671 124.929 85.393  1.00 37.35  ? 400  VAL A CG1   1 
ATOM   2292  C  CG2   . VAL A 1 382  ? 107.679 126.150 87.556  1.00 37.35  ? 400  VAL A CG2   1 
ATOM   2293  N  N     . TRP A 1 383  ? 107.129 128.059 83.436  1.00 40.54  ? 401  TRP A N     1 
ATOM   2294  C  CA    . TRP A 1 383  ? 106.942 128.162 81.992  1.00 40.54  ? 401  TRP A CA    1 
ATOM   2295  C  C     . TRP A 1 383  ? 108.082 128.935 81.340  1.00 40.54  ? 401  TRP A C     1 
ATOM   2296  O  O     . TRP A 1 383  ? 108.574 128.550 80.271  1.00 40.54  ? 401  TRP A O     1 
ATOM   2297  C  CB    . TRP A 1 383  ? 105.600 128.824 81.689  1.00 40.54  ? 401  TRP A CB    1 
ATOM   2298  C  CG    . TRP A 1 383  ? 105.280 128.898 80.235  1.00 40.54  ? 401  TRP A CG    1 
ATOM   2299  C  CD1   . TRP A 1 383  ? 105.606 129.903 79.375  1.00 40.54  ? 401  TRP A CD1   1 
ATOM   2300  C  CD2   . TRP A 1 383  ? 104.564 127.928 79.468  1.00 40.54  ? 401  TRP A CD2   1 
ATOM   2301  N  NE1   . TRP A 1 383  ? 105.138 129.618 78.117  1.00 40.54  ? 401  TRP A NE1   1 
ATOM   2302  C  CE2   . TRP A 1 383  ? 104.494 128.409 78.147  1.00 40.54  ? 401  TRP A CE2   1 
ATOM   2303  C  CE3   . TRP A 1 383  ? 103.975 126.698 79.769  1.00 40.54  ? 401  TRP A CE3   1 
ATOM   2304  C  CZ2   . TRP A 1 383  ? 103.859 127.704 77.129  1.00 40.54  ? 401  TRP A CZ2   1 
ATOM   2305  C  CZ3   . TRP A 1 383  ? 103.345 126.002 78.761  1.00 40.54  ? 401  TRP A CZ3   1 
ATOM   2306  C  CH2   . TRP A 1 383  ? 103.292 126.504 77.455  1.00 40.54  ? 401  TRP A CH2   1 
ATOM   2307  N  N     . ALA A 1 384  ? 108.510 130.034 81.963  1.00 37.34  ? 402  ALA A N     1 
ATOM   2308  C  CA    . ALA A 1 384  ? 109.640 130.784 81.426  1.00 37.34  ? 402  ALA A CA    1 
ATOM   2309  C  C     . ALA A 1 384  ? 110.907 129.943 81.436  1.00 37.34  ? 402  ALA A C     1 
ATOM   2310  O  O     . ALA A 1 384  ? 111.692 129.972 80.479  1.00 37.34  ? 402  ALA A O     1 
ATOM   2311  C  CB    . ALA A 1 384  ? 109.846 132.071 82.221  1.00 37.34  ? 402  ALA A CB    1 
ATOM   2312  N  N     . THR A 1 385  ? 111.120 129.182 82.513  1.00 36.03  ? 403  THR A N     1 
ATOM   2313  C  CA    . THR A 1 385  ? 112.290 128.312 82.580  1.00 36.03  ? 403  THR A CA    1 
ATOM   2314  C  C     . THR A 1 385  ? 112.253 127.258 81.483  1.00 36.03  ? 403  THR A C     1 
ATOM   2315  O  O     . THR A 1 385  ? 113.278 126.964 80.862  1.00 36.03  ? 403  THR A O     1 
ATOM   2316  C  CB    . THR A 1 385  ? 112.378 127.651 83.955  1.00 36.03  ? 403  THR A CB    1 
ATOM   2317  O  OG1   . THR A 1 385  ? 112.353 128.659 84.974  1.00 36.03  ? 403  THR A OG1   1 
ATOM   2318  C  CG2   . THR A 1 385  ? 113.667 126.853 84.076  1.00 36.03  ? 403  THR A CG2   1 
ATOM   2319  N  N     . HIS A 1 386  ? 111.079 126.682 81.226  1.00 36.19  ? 404  HIS A N     1 
ATOM   2320  C  CA    . HIS A 1 386  ? 110.960 125.680 80.171  1.00 36.19  ? 404  HIS A CA    1 
ATOM   2321  C  C     . HIS A 1 386  ? 111.229 126.280 78.797  1.00 36.19  ? 404  HIS A C     1 
ATOM   2322  O  O     . HIS A 1 386  ? 111.923 125.675 77.970  1.00 36.19  ? 404  HIS A O     1 
ATOM   2323  C  CB    . HIS A 1 386  ? 109.573 125.051 80.208  1.00 36.19  ? 404  HIS A CB    1 
ATOM   2324  C  CG    . HIS A 1 386  ? 109.371 123.979 79.187  1.00 36.19  ? 404  HIS A CG    1 
ATOM   2325  N  ND1   . HIS A 1 386  ? 109.473 122.639 79.486  1.00 36.19  ? 404  HIS A ND1   1 
ATOM   2326  C  CD2   . HIS A 1 386  ? 109.076 124.049 77.868  1.00 36.19  ? 404  HIS A CD2   1 
ATOM   2327  C  CE1   . HIS A 1 386  ? 109.246 121.928 78.396  1.00 36.19  ? 404  HIS A CE1   1 
ATOM   2328  N  NE2   . HIS A 1 386  ? 109.003 122.760 77.400  1.00 36.19  ? 404  HIS A NE2   1 
ATOM   2329  N  N     . GLU A 1 387  ? 110.676 127.465 78.528  1.00 40.60  ? 405  GLU A N     1 
ATOM   2330  C  CA    . GLU A 1 387  ? 110.913 128.106 77.238  1.00 40.60  ? 405  GLU A CA    1 
ATOM   2331  C  C     . GLU A 1 387  ? 112.390 128.415 77.042  1.00 40.60  ? 405  GLU A C     1 
ATOM   2332  O  O     . GLU A 1 387  ? 112.951 128.175 75.962  1.00 40.60  ? 405  GLU A O     1 
ATOM   2333  C  CB    . GLU A 1 387  ? 110.085 129.385 77.123  1.00 40.60  ? 405  GLU A CB    1 
ATOM   2334  C  CG    . GLU A 1 387  ? 108.593 129.166 77.005  1.00 40.60  ? 405  GLU A CG    1 
ATOM   2335  C  CD    . GLU A 1 387  ? 107.840 130.467 76.826  1.00 40.60  ? 405  GLU A CD    1 
ATOM   2336  O  OE1   . GLU A 1 387  ? 108.430 131.535 77.091  1.00 40.60  ? 405  GLU A OE1   1 
ATOM   2337  O  OE2   . GLU A 1 387  ? 106.661 130.423 76.416  1.00 40.60  ? 405  GLU A OE2   1 
ATOM   2338  N  N     . VAL A 1 388  ? 113.047 128.939 78.076  1.00 36.75  ? 406  VAL A N     1 
ATOM   2339  C  CA    . VAL A 1 388  ? 114.456 129.265 77.911  1.00 36.75  ? 406  VAL A CA    1 
ATOM   2340  C  C     . VAL A 1 388  ? 115.303 127.999 77.850  1.00 36.75  ? 406  VAL A C     1 
ATOM   2341  O  O     . VAL A 1 388  ? 116.347 127.983 77.193  1.00 36.75  ? 406  VAL A O     1 
ATOM   2342  C  CB    . VAL A 1 388  ? 114.924 130.228 79.014  1.00 36.75  ? 406  VAL A CB    1 
ATOM   2343  C  CG1   . VAL A 1 388  ? 114.958 129.541 80.356  1.00 36.75  ? 406  VAL A CG1   1 
ATOM   2344  C  CG2   . VAL A 1 388  ? 116.274 130.783 78.656  1.00 36.75  ? 406  VAL A CG2   1 
ATOM   2345  N  N     . PHE A 1 389  ? 114.872 126.914 78.499  1.00 36.07  ? 407  PHE A N     1 
ATOM   2346  C  CA    . PHE A 1 389  ? 115.562 125.639 78.323  1.00 36.07  ? 407  PHE A CA    1 
ATOM   2347  C  C     . PHE A 1 389  ? 115.464 125.165 76.881  1.00 36.07  ? 407  PHE A C     1 
ATOM   2348  O  O     . PHE A 1 389  ? 116.439 124.652 76.317  1.00 36.07  ? 407  PHE A O     1 
ATOM   2349  C  CB    . PHE A 1 389  ? 114.987 124.581 79.265  1.00 36.07  ? 407  PHE A CB    1 
ATOM   2350  C  CG    . PHE A 1 389  ? 115.351 123.175 78.879  1.00 36.07  ? 407  PHE A CG    1 
ATOM   2351  C  CD1   . PHE A 1 389  ? 116.612 122.672 79.149  1.00 36.07  ? 407  PHE A CD1   1 
ATOM   2352  C  CD2   . PHE A 1 389  ? 114.436 122.361 78.236  1.00 36.07  ? 407  PHE A CD2   1 
ATOM   2353  C  CE1   . PHE A 1 389  ? 116.952 121.384 78.788  1.00 36.07  ? 407  PHE A CE1   1 
ATOM   2354  C  CE2   . PHE A 1 389  ? 114.772 121.075 77.871  1.00 36.07  ? 407  PHE A CE2   1 
ATOM   2355  C  CZ    . PHE A 1 389  ? 116.030 120.585 78.150  1.00 36.07  ? 407  PHE A CZ    1 
ATOM   2356  N  N     . GLN A 1 390  ? 114.284 125.313 76.276  1.00 36.46  ? 408  GLN A N     1 
ATOM   2357  C  CA    . GLN A 1 390  ? 114.141 124.990 74.862  1.00 36.46  ? 408  GLN A CA    1 
ATOM   2358  C  C     . GLN A 1 390  ? 115.080 125.836 74.015  1.00 36.46  ? 408  GLN A C     1 
ATOM   2359  O  O     . GLN A 1 390  ? 115.693 125.337 73.065  1.00 36.46  ? 408  GLN A O     1 
ATOM   2360  C  CB    . GLN A 1 390  ? 112.695 125.194 74.415  1.00 36.46  ? 408  GLN A CB    1 
ATOM   2361  C  CG    . GLN A 1 390  ? 111.713 124.194 74.985  1.00 36.46  ? 408  GLN A CG    1 
ATOM   2362  C  CD    . GLN A 1 390  ? 110.363 124.266 74.302  1.00 36.46  ? 408  GLN A CD    1 
ATOM   2363  O  OE1   . GLN A 1 390  ? 110.064 125.228 73.595  1.00 36.46  ? 408  GLN A OE1   1 
ATOM   2364  N  NE2   . GLN A 1 390  ? 109.542 123.243 74.502  1.00 36.46  ? 408  GLN A NE2   1 
ATOM   2365  N  N     . GLN A 1 391  ? 115.206 127.120 74.346  1.00 38.10  ? 409  GLN A N     1 
ATOM   2366  C  CA    . GLN A 1 391  ? 116.079 127.991 73.565  1.00 38.10  ? 409  GLN A CA    1 
ATOM   2367  C  C     . GLN A 1 391  ? 117.560 127.765 73.854  1.00 38.10  ? 409  GLN A C     1 
ATOM   2368  O  O     . GLN A 1 391  ? 118.403 128.209 73.068  1.00 38.10  ? 409  GLN A O     1 
ATOM   2369  C  CB    . GLN A 1 391  ? 115.721 129.456 73.815  1.00 38.10  ? 409  GLN A CB    1 
ATOM   2370  C  CG    . GLN A 1 391  ? 114.323 129.823 73.361  1.00 38.10  ? 409  GLN A CG    1 
ATOM   2371  C  CD    . GLN A 1 391  ? 114.084 129.483 71.907  1.00 38.10  ? 409  GLN A CD    1 
ATOM   2372  O  OE1   . GLN A 1 391  ? 113.142 128.765 71.572  1.00 38.10  ? 409  GLN A OE1   1 
ATOM   2373  N  NE2   . GLN A 1 391  ? 114.938 129.998 71.032  1.00 38.10  ? 409  GLN A NE2   1 
ATOM   2374  N  N     . GLN A 1 392  ? 117.898 127.096 74.956  1.00 33.28  ? 410  GLN A N     1 
ATOM   2375  C  CA    . GLN A 1 392  ? 119.288 126.946 75.375  1.00 33.28  ? 410  GLN A CA    1 
ATOM   2376  C  C     . GLN A 1 392  ? 119.895 125.589 75.052  1.00 33.28  ? 410  GLN A C     1 
ATOM   2377  O  O     . GLN A 1 392  ? 121.063 125.528 74.658  1.00 33.28  ? 410  GLN A O     1 
ATOM   2378  C  CB    . GLN A 1 392  ? 119.413 127.194 76.879  1.00 33.28  ? 410  GLN A CB    1 
ATOM   2379  C  CG    . GLN A 1 392  ? 119.394 128.651 77.268  1.00 33.28  ? 410  GLN A CG    1 
ATOM   2380  C  CD    . GLN A 1 392  ? 119.415 128.838 78.763  1.00 33.28  ? 410  GLN A CD    1 
ATOM   2381  O  OE1   . GLN A 1 392  ? 119.406 127.869 79.519  1.00 33.28  ? 410  GLN A OE1   1 
ATOM   2382  N  NE2   . GLN A 1 392  ? 119.440 130.088 79.201  1.00 33.28  ? 410  GLN A NE2   1 
ATOM   2383  N  N     . LEU A 1 393  ? 119.148 124.497 75.224  1.00 33.14  ? 411  LEU A N     1 
ATOM   2384  C  CA    . LEU A 1 393  ? 119.746 123.169 75.083  1.00 33.14  ? 411  LEU A CA    1 
ATOM   2385  C  C     . LEU A 1 393  ? 120.429 122.957 73.737  1.00 33.14  ? 411  LEU A C     1 
ATOM   2386  O  O     . LEU A 1 393  ? 121.577 122.476 73.725  1.00 33.14  ? 411  LEU A O     1 
ATOM   2387  C  CB    . LEU A 1 393  ? 118.689 122.092 75.345  1.00 33.14  ? 411  LEU A CB    1 
ATOM   2388  C  CG    . LEU A 1 393  ? 119.197 120.659 75.185  1.00 33.14  ? 411  LEU A CG    1 
ATOM   2389  C  CD1   . LEU A 1 393  ? 120.153 120.305 76.309  1.00 33.14  ? 411  LEU A CD1   1 
ATOM   2390  C  CD2   . LEU A 1 393  ? 118.044 119.680 75.128  1.00 33.14  ? 411  LEU A CD2   1 
ATOM   2391  N  N     . PRO A 1 394  ? 119.810 123.264 72.587  1.00 31.31  ? 412  PRO A N     1 
ATOM   2392  C  CA    . PRO A 1 394  ? 120.563 123.146 71.327  1.00 31.31  ? 412  PRO A CA    1 
ATOM   2393  C  C     . PRO A 1 394  ? 121.805 124.013 71.300  1.00 31.31  ? 412  PRO A C     1 
ATOM   2394  O  O     . PRO A 1 394  ? 122.850 123.576 70.805  1.00 31.31  ? 412  PRO A O     1 
ATOM   2395  C  CB    . PRO A 1 394  ? 119.541 123.579 70.268  1.00 31.31  ? 412  PRO A CB    1 
ATOM   2396  C  CG    . PRO A 1 394  ? 118.226 123.321 70.888  1.00 31.31  ? 412  PRO A CG    1 
ATOM   2397  C  CD    . PRO A 1 394  ? 118.407 123.636 72.338  1.00 31.31  ? 412  PRO A CD    1 
ATOM   2398  N  N     . LEU A 1 395  ? 121.726 125.226 71.850  1.00 31.08  ? 413  LEU A N     1 
ATOM   2399  C  CA    . LEU A 1 395  ? 122.897 126.095 71.890  1.00 31.08  ? 413  LEU A CA    1 
ATOM   2400  C  C     . LEU A 1 395  ? 123.999 125.495 72.749  1.00 31.08  ? 413  LEU A C     1 
ATOM   2401  O  O     . LEU A 1 395  ? 125.181 125.571 72.397  1.00 31.08  ? 413  LEU A O     1 
ATOM   2402  C  CB    . LEU A 1 395  ? 122.512 127.476 72.418  1.00 31.08  ? 413  LEU A CB    1 
ATOM   2403  C  CG    . LEU A 1 395  ? 121.417 128.240 71.679  1.00 31.08  ? 413  LEU A CG    1 
ATOM   2404  C  CD1   . LEU A 1 395  ? 121.248 129.621 72.288  1.00 31.08  ? 413  LEU A CD1   1 
ATOM   2405  C  CD2   . LEU A 1 395  ? 121.739 128.338 70.200  1.00 31.08  ? 413  LEU A CD2   1 
ATOM   2406  N  N     . PHE A 1 396  ? 123.633 124.899 73.885  1.00 30.48  ? 414  PHE A N     1 
ATOM   2407  C  CA    . PHE A 1 396  ? 124.633 124.291 74.753  1.00 30.48  ? 414  PHE A CA    1 
ATOM   2408  C  C     . PHE A 1 396  ? 125.298 123.102 74.074  1.00 30.48  ? 414  PHE A C     1 
ATOM   2409  O  O     . PHE A 1 396  ? 126.530 122.989 74.065  1.00 30.48  ? 414  PHE A O     1 
ATOM   2410  C  CB    . PHE A 1 396  ? 123.998 123.871 76.078  1.00 30.48  ? 414  PHE A CB    1 
ATOM   2411  C  CG    . PHE A 1 396  ? 124.976 123.294 77.056  1.00 30.48  ? 414  PHE A CG    1 
ATOM   2412  C  CD1   . PHE A 1 396  ? 125.929 124.100 77.654  1.00 30.48  ? 414  PHE A CD1   1 
ATOM   2413  C  CD2   . PHE A 1 396  ? 124.945 121.949 77.377  1.00 30.48  ? 414  PHE A CD2   1 
ATOM   2414  C  CE1   . PHE A 1 396  ? 126.832 123.576 78.551  1.00 30.48  ? 414  PHE A CE1   1 
ATOM   2415  C  CE2   . PHE A 1 396  ? 125.847 121.420 78.276  1.00 30.48  ? 414  PHE A CE2   1 
ATOM   2416  C  CZ    . PHE A 1 396  ? 126.791 122.235 78.862  1.00 30.48  ? 414  PHE A CZ    1 
ATOM   2417  N  N     . LEU A 1 397  ? 124.498 122.203 73.493  1.00 28.88  ? 415  LEU A N     1 
ATOM   2418  C  CA    . LEU A 1 397  ? 125.077 121.044 72.819  1.00 28.88  ? 415  LEU A CA    1 
ATOM   2419  C  C     . LEU A 1 397  ? 125.891 121.449 71.597  1.00 28.88  ? 415  LEU A C     1 
ATOM   2420  O  O     . LEU A 1 397  ? 126.802 120.720 71.192  1.00 28.88  ? 415  LEU A O     1 
ATOM   2421  C  CB    . LEU A 1 397  ? 123.981 120.060 72.420  1.00 28.88  ? 415  LEU A CB    1 
ATOM   2422  C  CG    . LEU A 1 397  ? 123.242 119.379 73.568  1.00 28.88  ? 415  LEU A CG    1 
ATOM   2423  C  CD1   . LEU A 1 397  ? 122.288 118.329 73.032  1.00 28.88  ? 415  LEU A CD1   1 
ATOM   2424  C  CD2   . LEU A 1 397  ? 124.229 118.763 74.539  1.00 28.88  ? 415  LEU A CD2   1 
ATOM   2425  N  N     . GLU A 1 398  ? 125.578 122.597 70.991  1.00 32.46  ? 416  GLU A N     1 
ATOM   2426  C  CA    . GLU A 1 398  ? 126.401 123.092 69.893  1.00 32.46  ? 416  GLU A CA    1 
ATOM   2427  C  C     . GLU A 1 398  ? 127.719 123.659 70.401  1.00 32.46  ? 416  GLU A C     1 
ATOM   2428  O  O     . GLU A 1 398  ? 128.776 123.415 69.807  1.00 32.46  ? 416  GLU A O     1 
ATOM   2429  C  CB    . GLU A 1 398  ? 125.635 124.154 69.106  1.00 32.46  ? 416  GLU A CB    1 
ATOM   2430  C  CG    . GLU A 1 398  ? 126.526 125.087 68.306  1.00 32.46  ? 416  GLU A CG    1 
ATOM   2431  C  CD    . GLU A 1 398  ? 125.821 126.366 67.910  1.00 32.46  ? 416  GLU A CD    1 
ATOM   2432  O  OE1   . GLU A 1 398  ? 124.579 126.347 67.782  1.00 32.46  ? 416  GLU A OE1   1 
ATOM   2433  O  OE2   . GLU A 1 398  ? 126.509 127.394 67.736  1.00 32.46  ? 416  GLU A OE2   1 
ATOM   2434  N  N     . ARG A 1 399  ? 127.678 124.416 71.495  1.00 33.04  ? 417  ARG A N     1 
ATOM   2435  C  CA    . ARG A 1 399  ? 128.853 125.106 72.009  1.00 33.04  ? 417  ARG A CA    1 
ATOM   2436  C  C     . ARG A 1 399  ? 129.689 124.256 72.957  1.00 33.04  ? 417  ARG A C     1 
ATOM   2437  O  O     . ARG A 1 399  ? 130.836 124.619 73.237  1.00 33.04  ? 417  ARG A O     1 
ATOM   2438  C  CB    . ARG A 1 399  ? 128.430 126.399 72.713  1.00 33.04  ? 417  ARG A CB    1 
ATOM   2439  C  CG    . ARG A 1 399  ? 127.656 127.352 71.821  1.00 33.04  ? 417  ARG A CG    1 
ATOM   2440  C  CD    . ARG A 1 399  ? 127.315 128.635 72.544  1.00 33.04  ? 417  ARG A CD    1 
ATOM   2441  N  NE    . ARG A 1 399  ? 128.506 129.429 72.809  1.00 33.04  ? 417  ARG A NE    1 
ATOM   2442  C  CZ    . ARG A 1 399  ? 129.071 130.239 71.925  1.00 33.04  ? 417  ARG A CZ    1 
ATOM   2443  N  NH1   . ARG A 1 399  ? 128.582 130.379 70.705  1.00 33.04  ? 417  ARG A NH1   1 
ATOM   2444  N  NH2   . ARG A 1 399  ? 130.155 130.926 72.273  1.00 33.04  ? 417  ARG A NH2   1 
ATOM   2445  N  N     . CYS A 1 400  ? 129.151 123.144 73.453  1.00 30.37  ? 418  CYS A N     1 
ATOM   2446  C  CA    . CYS A 1 400  ? 129.882 122.212 74.312  1.00 30.37  ? 418  CYS A CA    1 
ATOM   2447  C  C     . CYS A 1 400  ? 129.744 120.824 73.704  1.00 30.37  ? 418  CYS A C     1 
ATOM   2448  O  O     . CYS A 1 400  ? 128.985 119.983 74.204  1.00 30.37  ? 418  CYS A O     1 
ATOM   2449  C  CB    . CYS A 1 400  ? 129.365 122.256 75.750  1.00 30.37  ? 418  CYS A CB    1 
ATOM   2450  S  SG    . CYS A 1 400  ? 129.767 123.779 76.638  1.00 30.37  ? 418  CYS A SG    1 
ATOM   2451  N  N     . PRO A 1 401  ? 130.478 120.547 72.622  1.00 29.40  ? 419  PRO A N     1 
ATOM   2452  C  CA    . PRO A 1 401  ? 130.209 119.317 71.859  1.00 29.40  ? 419  PRO A CA    1 
ATOM   2453  C  C     . PRO A 1 401  ? 130.657 118.049 72.562  1.00 29.40  ? 419  PRO A C     1 
ATOM   2454  O  O     . PRO A 1 401  ? 129.990 117.015 72.434  1.00 29.40  ? 419  PRO A O     1 
ATOM   2455  C  CB    . PRO A 1 401  ? 130.986 119.542 70.551  1.00 29.40  ? 419  PRO A CB    1 
ATOM   2456  C  CG    . PRO A 1 401  ? 131.388 120.997 70.556  1.00 29.40  ? 419  PRO A CG    1 
ATOM   2457  C  CD    . PRO A 1 401  ? 131.518 121.371 71.990  1.00 29.40  ? 419  PRO A CD    1 
ATOM   2458  N  N     . HIS A 1 402  ? 131.766 118.094 73.293  1.00 29.98  ? 420  HIS A N     1 
ATOM   2459  C  CA    . HIS A 1 402  ? 132.325 116.880 73.881  1.00 29.98  ? 420  HIS A CA    1 
ATOM   2460  C  C     . HIS A 1 402  ? 131.388 116.330 74.951  1.00 29.98  ? 420  HIS A C     1 
ATOM   2461  O  O     . HIS A 1 402  ? 130.966 117.078 75.841  1.00 29.98  ? 420  HIS A O     1 
ATOM   2462  C  CB    . HIS A 1 402  ? 133.698 117.162 74.484  1.00 29.98  ? 420  HIS A CB    1 
ATOM   2463  C  CG    . HIS A 1 402  ? 134.646 116.008 74.391  1.00 29.98  ? 420  HIS A CG    1 
ATOM   2464  N  ND1   . HIS A 1 402  ? 134.371 114.771 74.933  1.00 29.98  ? 420  HIS A ND1   1 
ATOM   2465  C  CD2   . HIS A 1 402  ? 135.868 115.904 73.819  1.00 29.98  ? 420  HIS A CD2   1 
ATOM   2466  C  CE1   . HIS A 1 402  ? 135.382 113.954 74.696  1.00 29.98  ? 420  HIS A CE1   1 
ATOM   2467  N  NE2   . HIS A 1 402  ? 136.304 114.617 74.024  1.00 29.98  ? 420  HIS A NE2   1 
ATOM   2468  N  N     . PRO A 1 403  ? 131.045 115.041 74.903  1.00 25.90  ? 421  PRO A N     1 
ATOM   2469  C  CA    . PRO A 1 403  ? 130.163 114.474 75.936  1.00 25.90  ? 421  PRO A CA    1 
ATOM   2470  C  C     . PRO A 1 403  ? 130.748 114.537 77.335  1.00 25.90  ? 421  PRO A C     1 
ATOM   2471  O  O     . PRO A 1 403  ? 129.991 114.456 78.313  1.00 25.90  ? 421  PRO A O     1 
ATOM   2472  C  CB    . PRO A 1 403  ? 129.972 113.022 75.476  1.00 25.90  ? 421  PRO A CB    1 
ATOM   2473  C  CG    . PRO A 1 403  ? 130.307 113.030 74.023  1.00 25.90  ? 421  PRO A CG    1 
ATOM   2474  C  CD    . PRO A 1 403  ? 131.376 114.058 73.860  1.00 25.90  ? 421  PRO A CD    1 
ATOM   2475  N  N     . VAL A 1 404  ? 132.069 114.673 77.462  1.00 26.39  ? 422  VAL A N     1 
ATOM   2476  C  CA    . VAL A 1 404  ? 132.690 114.751 78.781  1.00 26.39  ? 422  VAL A CA    1 
ATOM   2477  C  C     . VAL A 1 404  ? 132.199 115.982 79.528  1.00 26.39  ? 422  VAL A C     1 
ATOM   2478  O  O     . VAL A 1 404  ? 132.011 115.947 80.748  1.00 26.39  ? 422  VAL A O     1 
ATOM   2479  C  CB    . VAL A 1 404  ? 134.225 114.736 78.655  1.00 26.39  ? 422  VAL A CB    1 
ATOM   2480  C  CG1   . VAL A 1 404  ? 134.872 114.920 80.014  1.00 26.39  ? 422  VAL A CG1   1 
ATOM   2481  C  CG2   . VAL A 1 404  ? 134.685 113.438 78.023  1.00 26.39  ? 422  VAL A CG2   1 
ATOM   2482  N  N     . THR A 1 405  ? 131.976 117.086 78.812  1.00 24.95  ? 423  THR A N     1 
ATOM   2483  C  CA    . THR A 1 405  ? 131.501 118.304 79.463  1.00 24.95  ? 423  THR A CA    1 
ATOM   2484  C  C     . THR A 1 405  ? 130.150 118.081 80.129  1.00 24.95  ? 423  THR A C     1 
ATOM   2485  O  O     . THR A 1 405  ? 129.975 118.364 81.321  1.00 24.95  ? 423  THR A O     1 
ATOM   2486  C  CB    . THR A 1 405  ? 131.407 119.439 78.446  1.00 24.95  ? 423  THR A CB    1 
ATOM   2487  O  OG1   . THR A 1 405  ? 132.723 119.853 78.063  1.00 24.95  ? 423  THR A OG1   1 
ATOM   2488  C  CG2   . THR A 1 405  ? 130.666 120.616 79.043  1.00 24.95  ? 423  THR A CG2   1 
ATOM   2489  N  N     . LEU A 1 406  ? 129.184 117.559 79.373  1.00 23.98  ? 424  LEU A N     1 
ATOM   2490  C  CA    . LEU A 1 406  ? 127.860 117.328 79.935  1.00 23.98  ? 424  LEU A CA    1 
ATOM   2491  C  C     . LEU A 1 406  ? 127.901 116.268 81.026  1.00 23.98  ? 424  LEU A C     1 
ATOM   2492  O  O     . LEU A 1 406  ? 127.205 116.390 82.038  1.00 23.98  ? 424  LEU A O     1 
ATOM   2493  C  CB    . LEU A 1 406  ? 126.878 116.925 78.837  1.00 23.98  ? 424  LEU A CB    1 
ATOM   2494  C  CG    . LEU A 1 406  ? 125.431 116.806 79.314  1.00 23.98  ? 424  LEU A CG    1 
ATOM   2495  C  CD1   . LEU A 1 406  ? 124.847 118.182 79.574  1.00 23.98  ? 424  LEU A CD1   1 
ATOM   2496  C  CD2   . LEU A 1 406  ? 124.586 116.038 78.320  1.00 23.98  ? 424  LEU A CD2   1 
ATOM   2497  N  N     . ALA A 1 407  ? 128.704 115.216 80.841  1.00 23.40  ? 425  ALA A N     1 
ATOM   2498  C  CA    . ALA A 1 407  ? 128.771 114.170 81.856  1.00 23.40  ? 425  ALA A CA    1 
ATOM   2499  C  C     . ALA A 1 407  ? 129.348 114.704 83.162  1.00 23.40  ? 425  ALA A C     1 
ATOM   2500  O  O     . ALA A 1 407  ? 128.818 114.426 84.248  1.00 23.40  ? 425  ALA A O     1 
ATOM   2501  C  CB    . ALA A 1 407  ? 129.592 112.991 81.341  1.00 23.40  ? 425  ALA A CB    1 
ATOM   2502  N  N     . GLY A 1 408  ? 130.422 115.489 83.076  1.00 22.72  ? 426  GLY A N     1 
ATOM   2503  C  CA    . GLY A 1 408  ? 130.986 116.091 84.270  1.00 22.72  ? 426  GLY A CA    1 
ATOM   2504  C  C     . GLY A 1 408  ? 130.027 117.053 84.939  1.00 22.72  ? 426  GLY A C     1 
ATOM   2505  O  O     . GLY A 1 408  ? 129.917 117.076 86.165  1.00 22.72  ? 426  GLY A O     1 
ATOM   2506  N  N     . MET A 1 409  ? 129.309 117.852 84.143  1.00 22.12  ? 427  MET A N     1 
ATOM   2507  C  CA    . MET A 1 409  ? 128.304 118.742 84.717  1.00 22.12  ? 427  MET A CA    1 
ATOM   2508  C  C     . MET A 1 409  ? 127.210 117.958 85.424  1.00 22.12  ? 427  MET A C     1 
ATOM   2509  O  O     . MET A 1 409  ? 126.745 118.356 86.497  1.00 22.12  ? 427  MET A O     1 
ATOM   2510  C  CB    . MET A 1 409  ? 127.705 119.633 83.631  1.00 22.12  ? 427  MET A CB    1 
ATOM   2511  C  CG    . MET A 1 409  ? 128.407 120.967 83.470  1.00 22.12  ? 427  MET A CG    1 
ATOM   2512  S  SD    . MET A 1 409  ? 127.599 122.027 82.258  1.00 22.12  ? 427  MET A SD    1 
ATOM   2513  C  CE    . MET A 1 409  ? 125.894 121.942 82.806  1.00 22.12  ? 427  MET A CE    1 
ATOM   2514  N  N     . LEU A 1 410  ? 126.780 116.842 84.836  1.00 20.43  ? 428  LEU A N     1 
ATOM   2515  C  CA    . LEU A 1 410  ? 125.750 116.024 85.465  1.00 20.43  ? 428  LEU A CA    1 
ATOM   2516  C  C     . LEU A 1 410  ? 126.254 115.360 86.737  1.00 20.43  ? 428  LEU A C     1 
ATOM   2517  O  O     . LEU A 1 410  ? 125.456 115.062 87.631  1.00 20.43  ? 428  LEU A O     1 
ATOM   2518  C  CB    . LEU A 1 410  ? 125.242 114.964 84.488  1.00 20.43  ? 428  LEU A CB    1 
ATOM   2519  C  CG    . LEU A 1 410  ? 124.452 115.444 83.270  1.00 20.43  ? 428  LEU A CG    1 
ATOM   2520  C  CD1   . LEU A 1 410  ? 124.021 114.264 82.418  1.00 20.43  ? 428  LEU A CD1   1 
ATOM   2521  C  CD2   . LEU A 1 410  ? 123.252 116.262 83.700  1.00 20.43  ? 428  LEU A CD2   1 
ATOM   2522  N  N     . GLU A 1 411  ? 127.561 115.115 86.841  1.00 20.80  ? 429  GLU A N     1 
ATOM   2523  C  CA    . GLU A 1 411  ? 128.108 114.507 88.048  1.00 20.80  ? 429  GLU A CA    1 
ATOM   2524  C  C     . GLU A 1 411  ? 128.740 115.514 89.004  1.00 20.80  ? 429  GLU A C     1 
ATOM   2525  O  O     . GLU A 1 411  ? 128.884 115.208 90.191  1.00 20.80  ? 429  GLU A O     1 
ATOM   2526  C  CB    . GLU A 1 411  ? 129.136 113.426 87.682  1.00 20.80  ? 429  GLU A CB    1 
ATOM   2527  C  CG    . GLU A 1 411  ? 129.510 112.478 88.825  1.00 20.80  ? 429  GLU A CG    1 
ATOM   2528  C  CD    . GLU A 1 411  ? 128.360 111.589 89.287  1.00 20.80  ? 429  GLU A CD    1 
ATOM   2529  O  OE1   . GLU A 1 411  ? 127.271 111.629 88.676  1.00 20.80  ? 429  GLU A OE1   1 
ATOM   2530  O  OE2   . GLU A 1 411  ? 128.552 110.839 90.268  1.00 20.80  ? 429  GLU A OE2   1 
ATOM   2531  N  N     . MET A 1 412  ? 129.120 116.700 88.523  1.00 18.67  ? 430  MET A N     1 
ATOM   2532  C  CA    . MET A 1 412  ? 129.607 117.744 89.416  1.00 18.67  ? 430  MET A CA    1 
ATOM   2533  C  C     . MET A 1 412  ? 128.503 118.303 90.307  1.00 18.67  ? 430  MET A C     1 
ATOM   2534  O  O     . MET A 1 412  ? 128.797 118.845 91.376  1.00 18.67  ? 430  MET A O     1 
ATOM   2535  C  CB    . MET A 1 412  ? 130.251 118.865 88.596  1.00 18.67  ? 430  MET A CB    1 
ATOM   2536  C  CG    . MET A 1 412  ? 130.684 120.078 89.385  1.00 18.67  ? 430  MET A CG    1 
ATOM   2537  S  SD    . MET A 1 412  ? 131.762 119.665 90.762  1.00 18.67  ? 430  MET A SD    1 
ATOM   2538  C  CE    . MET A 1 412  ? 131.493 121.091 91.807  1.00 18.67  ? 430  MET A CE    1 
ATOM   2539  N  N     . GLY A 1 413  ? 127.242 118.150 89.915  1.00 15.02  ? 431  GLY A N     1 
ATOM   2540  C  CA    . GLY A 1 413  ? 126.155 118.724 90.681  1.00 15.02  ? 431  GLY A CA    1 
ATOM   2541  C  C     . GLY A 1 413  ? 125.351 117.730 91.493  1.00 15.02  ? 431  GLY A C     1 
ATOM   2542  O  O     . GLY A 1 413  ? 124.144 117.909 91.670  1.00 15.02  ? 431  GLY A O     1 
ATOM   2543  N  N     . VAL A 1 414  ? 125.999 116.679 91.988  1.00 15.97  ? 432  VAL A N     1 
ATOM   2544  C  CA    . VAL A 1 414  ? 125.365 115.762 92.931  1.00 15.97  ? 432  VAL A CA    1 
ATOM   2545  C  C     . VAL A 1 414  ? 126.200 115.680 94.202  1.00 15.97  ? 432  VAL A C     1 
ATOM   2546  O  O     . VAL A 1 414  ? 126.291 114.618 94.828  1.00 15.97  ? 432  VAL A O     1 
ATOM   2547  C  CB    . VAL A 1 414  ? 125.151 114.364 92.323  1.00 15.97  ? 432  VAL A CB    1 
ATOM   2548  C  CG1   . VAL A 1 414  ? 123.924 114.361 91.429  1.00 15.97  ? 432  VAL A CG1   1 
ATOM   2549  C  CG2   . VAL A 1 414  ? 126.376 113.931 91.554  1.00 15.97  ? 432  VAL A CG2   1 
ATOM   2550  N  N     . SER A 1 415  ? 126.828 116.793 94.579  1.00 15.59  ? 433  SER A N     1 
ATOM   2551  C  CA    . SER A 1 415  ? 127.673 116.833 95.763  1.00 15.59  ? 433  SER A CA    1 
ATOM   2552  C  C     . SER A 1 415  ? 126.895 116.406 97.005  1.00 15.59  ? 433  SER A C     1 
ATOM   2553  O  O     . SER A 1 415  ? 125.666 116.502 97.069  1.00 15.59  ? 433  SER A O     1 
ATOM   2554  C  CB    . SER A 1 415  ? 128.245 118.234 95.961  1.00 15.59  ? 433  SER A CB    1 
ATOM   2555  O  OG    . SER A 1 415  ? 128.956 118.652 94.811  1.00 15.59  ? 433  SER A OG    1 
ATOM   2556  N  N     . TYR A 1 416  ? 127.635 115.936 98.009  1.00 16.45  ? 434  TYR A N     1 
ATOM   2557  C  CA    . TYR A 1 416  ? 127.022 115.278 99.162  1.00 16.45  ? 434  TYR A CA    1 
ATOM   2558  C  C     . TYR A 1 416  ? 128.001 115.336 100.326 1.00 16.45  ? 434  TYR A C     1 
ATOM   2559  O  O     . TYR A 1 416  ? 129.078 114.739 100.251 1.00 16.45  ? 434  TYR A O     1 
ATOM   2560  C  CB    . TYR A 1 416  ? 126.666 113.841 98.816  1.00 16.45  ? 434  TYR A CB    1 
ATOM   2561  C  CG    . TYR A 1 416  ? 125.907 113.115 99.892  1.00 16.45  ? 434  TYR A CG    1 
ATOM   2562  C  CD1   . TYR A 1 416  ? 126.568 112.435 100.898 1.00 16.45  ? 434  TYR A CD1   1 
ATOM   2563  C  CD2   . TYR A 1 416  ? 124.525 113.097 99.891  1.00 16.45  ? 434  TYR A CD2   1 
ATOM   2564  C  CE1   . TYR A 1 416  ? 125.872 111.768 101.877 1.00 16.45  ? 434  TYR A CE1   1 
ATOM   2565  C  CE2   . TYR A 1 416  ? 123.822 112.434 100.867 1.00 16.45  ? 434  TYR A CE2   1 
ATOM   2566  C  CZ    . TYR A 1 416  ? 124.500 111.767 101.853 1.00 16.45  ? 434  TYR A CZ    1 
ATOM   2567  O  OH    . TYR A 1 416  ? 123.793 111.108 102.828 1.00 16.45  ? 434  TYR A OH    1 
ATOM   2568  N  N     . LEU A 1 417  ? 127.625 116.028 101.394 1.00 14.66  ? 435  LEU A N     1 
ATOM   2569  C  CA    . LEU A 1 417  ? 128.479 116.177 102.572 1.00 14.66  ? 435  LEU A CA    1 
ATOM   2570  C  C     . LEU A 1 417  ? 127.823 115.545 103.789 1.00 14.66  ? 435  LEU A C     1 
ATOM   2571  O  O     . LEU A 1 417  ? 126.882 116.134 104.355 1.00 14.66  ? 435  LEU A O     1 
ATOM   2572  C  CB    . LEU A 1 417  ? 128.775 117.651 102.840 1.00 14.66  ? 435  LEU A CB    1 
ATOM   2573  C  CG    . LEU A 1 417  ? 129.516 118.378 101.722 1.00 14.66  ? 435  LEU A CG    1 
ATOM   2574  C  CD1   . LEU A 1 417  ? 130.010 119.727 102.193 1.00 14.66  ? 435  LEU A CD1   1 
ATOM   2575  C  CD2   . LEU A 1 417  ? 130.669 117.535 101.221 1.00 14.66  ? 435  LEU A CD2   1 
ATOM   2576  N  N     . PRO A 1 418  ? 128.267 114.373 104.235 1.00 16.99  ? 436  PRO A N     1 
ATOM   2577  C  CA    . PRO A 1 418  ? 127.650 113.754 105.409 1.00 16.99  ? 436  PRO A CA    1 
ATOM   2578  C  C     . PRO A 1 418  ? 128.060 114.468 106.685 1.00 16.99  ? 436  PRO A C     1 
ATOM   2579  O  O     . PRO A 1 418  ? 129.100 115.125 106.765 1.00 16.99  ? 436  PRO A O     1 
ATOM   2580  C  CB    . PRO A 1 418  ? 128.178 112.315 105.382 1.00 16.99  ? 436  PRO A CB    1 
ATOM   2581  C  CG    . PRO A 1 418  ? 129.102 112.230 104.198 1.00 16.99  ? 436  PRO A CG    1 
ATOM   2582  C  CD    . PRO A 1 418  ? 129.439 113.617 103.782 1.00 16.99  ? 436  PRO A CD    1 
ATOM   2583  N  N     . VAL A 1 419  ? 127.204 114.335 107.694 1.00 20.53  ? 437  VAL A N     1 
ATOM   2584  C  CA    . VAL A 1 419  ? 127.383 114.963 108.990 1.00 20.53  ? 437  VAL A CA    1 
ATOM   2585  C  C     . VAL A 1 419  ? 126.868 114.009 110.062 1.00 20.53  ? 437  VAL A C     1 
ATOM   2586  O  O     . VAL A 1 419  ? 126.398 112.907 109.773 1.00 20.53  ? 437  VAL A O     1 
ATOM   2587  C  CB    . VAL A 1 419  ? 126.670 116.328 109.083 1.00 20.53  ? 437  VAL A CB    1 
ATOM   2588  C  CG1   . VAL A 1 419  ? 127.472 117.400 108.362 1.00 20.53  ? 437  VAL A CG1   1 
ATOM   2589  C  CG2   . VAL A 1 419  ? 125.273 116.227 108.504 1.00 20.53  ? 437  VAL A CG2   1 
ATOM   2590  N  N     . ASN A 1 420  ? 126.975 114.443 111.313 1.00 24.69  ? 438  ASN A N     1 
ATOM   2591  C  CA    . ASN A 1 420  ? 126.567 113.656 112.466 1.00 24.69  ? 438  ASN A CA    1 
ATOM   2592  C  C     . ASN A 1 420  ? 126.074 114.621 113.535 1.00 24.69  ? 438  ASN A C     1 
ATOM   2593  O  O     . ASN A 1 420  ? 125.917 115.819 113.284 1.00 24.69  ? 438  ASN A O     1 
ATOM   2594  C  CB    . ASN A 1 420  ? 127.730 112.786 112.952 1.00 24.69  ? 438  ASN A CB    1 
ATOM   2595  C  CG    . ASN A 1 420  ? 129.057 113.507 112.872 1.00 24.69  ? 438  ASN A CG    1 
ATOM   2596  O  OD1   . ASN A 1 420  ? 129.106 114.709 112.610 1.00 24.69  ? 438  ASN A OD1   1 
ATOM   2597  N  ND2   . ASN A 1 420  ? 130.143 112.779 113.092 1.00 24.69  ? 438  ASN A ND2   1 
ATOM   2598  N  N     . GLN A 1 421  ? 125.838 114.105 114.742 1.00 24.58  ? 439  GLN A N     1 
ATOM   2599  C  CA    . GLN A 1 421  ? 125.347 114.967 115.812 1.00 24.58  ? 439  GLN A CA    1 
ATOM   2600  C  C     . GLN A 1 421  ? 126.368 116.018 116.226 1.00 24.58  ? 439  GLN A C     1 
ATOM   2601  O  O     . GLN A 1 421  ? 126.003 116.980 116.906 1.00 24.58  ? 439  GLN A O     1 
ATOM   2602  C  CB    . GLN A 1 421  ? 124.936 114.138 117.028 1.00 24.58  ? 439  GLN A CB    1 
ATOM   2603  C  CG    . GLN A 1 421  ? 126.083 113.728 117.928 1.00 24.58  ? 439  GLN A CG    1 
ATOM   2604  C  CD    . GLN A 1 421  ? 126.838 112.532 117.399 1.00 24.58  ? 439  GLN A CD    1 
ATOM   2605  O  OE1   . GLN A 1 421  ? 126.304 111.739 116.626 1.00 24.58  ? 439  GLN A OE1   1 
ATOM   2606  N  NE2   . GLN A 1 421  ? 128.091 112.396 117.812 1.00 24.58  ? 439  GLN A NE2   1 
ATOM   2607  N  N     . ASN A 1 422  ? 127.632 115.862 115.830 1.00 23.73  ? 440  ASN A N     1 
ATOM   2608  C  CA    . ASN A 1 422  ? 128.651 116.855 116.143 1.00 23.73  ? 440  ASN A CA    1 
ATOM   2609  C  C     . ASN A 1 422  ? 128.492 118.135 115.336 1.00 23.73  ? 440  ASN A C     1 
ATOM   2610  O  O     . ASN A 1 422  ? 129.209 119.104 115.604 1.00 23.73  ? 440  ASN A O     1 
ATOM   2611  C  CB    . ASN A 1 422  ? 130.046 116.278 115.906 1.00 23.73  ? 440  ASN A CB    1 
ATOM   2612  C  CG    . ASN A 1 422  ? 130.266 114.970 116.634 1.00 23.73  ? 440  ASN A CG    1 
ATOM   2613  O  OD1   . ASN A 1 422  ? 129.320 114.346 117.110 1.00 23.73  ? 440  ASN A OD1   1 
ATOM   2614  N  ND2   . ASN A 1 422  ? 131.518 114.543 116.718 1.00 23.73  ? 440  ASN A ND2   1 
ATOM   2615  N  N     . TRP A 1 423  ? 127.597 118.159 114.347 1.00 22.29  ? 441  TRP A N     1 
ATOM   2616  C  CA    . TRP A 1 423  ? 127.312 119.412 113.656 1.00 22.29  ? 441  TRP A CA    1 
ATOM   2617  C  C     . TRP A 1 423  ? 126.567 120.379 114.567 1.00 22.29  ? 441  TRP A C     1 
ATOM   2618  O  O     . TRP A 1 423  ? 126.910 121.565 114.637 1.00 22.29  ? 441  TRP A O     1 
ATOM   2619  C  CB    . TRP A 1 423  ? 126.517 119.146 112.378 1.00 22.29  ? 441  TRP A CB    1 
ATOM   2620  C  CG    . TRP A 1 423  ? 126.136 120.396 111.648 1.00 22.29  ? 441  TRP A CG    1 
ATOM   2621  C  CD1   . TRP A 1 423  ? 124.892 120.938 111.552 1.00 22.29  ? 441  TRP A CD1   1 
ATOM   2622  C  CD2   . TRP A 1 423  ? 127.012 121.272 110.927 1.00 22.29  ? 441  TRP A CD2   1 
ATOM   2623  N  NE1   . TRP A 1 423  ? 124.933 122.093 110.812 1.00 22.29  ? 441  TRP A NE1   1 
ATOM   2624  C  CE2   . TRP A 1 423  ? 126.224 122.321 110.415 1.00 22.29  ? 441  TRP A CE2   1 
ATOM   2625  C  CE3   . TRP A 1 423  ? 128.383 121.270 110.661 1.00 22.29  ? 441  TRP A CE3   1 
ATOM   2626  C  CZ2   . TRP A 1 423  ? 126.761 123.357 109.654 1.00 22.29  ? 441  TRP A CZ2   1 
ATOM   2627  C  CZ3   . TRP A 1 423  ? 128.915 122.301 109.905 1.00 22.29  ? 441  TRP A CZ3   1 
ATOM   2628  C  CH2   . TRP A 1 423  ? 128.105 123.330 109.411 1.00 22.29  ? 441  TRP A CH2   1 
ATOM   2629  N  N     . GLU A 1 424  ? 125.551 119.888 115.280 1.00 24.57  ? 442  GLU A N     1 
ATOM   2630  C  CA    . GLU A 1 424  ? 124.868 120.729 116.257 1.00 24.57  ? 442  GLU A CA    1 
ATOM   2631  C  C     . GLU A 1 424  ? 125.796 121.098 117.405 1.00 24.57  ? 442  GLU A C     1 
ATOM   2632  O  O     . GLU A 1 424  ? 125.714 122.207 117.940 1.00 24.57  ? 442  GLU A O     1 
ATOM   2633  C  CB    . GLU A 1 424  ? 123.614 120.029 116.777 1.00 24.57  ? 442  GLU A CB    1 
ATOM   2634  C  CG    . GLU A 1 424  ? 122.451 120.055 115.800 1.00 24.57  ? 442  GLU A CG    1 
ATOM   2635  C  CD    . GLU A 1 424  ? 121.158 119.551 116.411 1.00 24.57  ? 442  GLU A CD    1 
ATOM   2636  O  OE1   . GLU A 1 424  ? 121.219 118.848 117.441 1.00 24.57  ? 442  GLU A OE1   1 
ATOM   2637  O  OE2   . GLU A 1 424  ? 120.079 119.863 115.863 1.00 24.57  ? 442  GLU A OE2   1 
ATOM   2638  N  N     . ARG A 1 425  ? 126.735 120.247 117.775 1.00 24.22  ? 443  ARG A N     1 
ATOM   2639  C  CA    . ARG A 1 425  ? 127.696 120.644 118.797 1.00 24.22  ? 443  ARG A CA    1 
ATOM   2640  C  C     . ARG A 1 425  ? 128.632 121.684 118.227 1.00 24.22  ? 443  ARG A C     1 
ATOM   2641  O  O     . ARG A 1 425  ? 128.996 122.631 118.910 1.00 24.22  ? 443  ARG A O     1 
ATOM   2642  C  CB    . ARG A 1 425  ? 128.503 119.457 119.287 1.00 24.22  ? 443  ARG A CB    1 
ATOM   2643  C  CG    . ARG A 1 425  ? 127.669 118.347 119.893 1.00 24.22  ? 443  ARG A CG    1 
ATOM   2644  C  CD    . ARG A 1 425  ? 128.525 117.124 120.160 1.00 24.22  ? 443  ARG A CD    1 
ATOM   2645  N  NE    . ARG A 1 425  ? 127.750 116.031 120.736 1.00 24.22  ? 443  ARG A NE    1 
ATOM   2646  C  CZ    . ARG A 1 425  ? 128.244 114.825 120.987 1.00 24.22  ? 443  ARG A CZ    1 
ATOM   2647  N  NH1   . ARG A 1 425  ? 129.511 114.557 120.709 1.00 24.22  ? 443  ARG A NH1   1 
ATOM   2648  N  NH2   . ARG A 1 425  ? 127.471 113.887 121.513 1.00 24.22  ? 443  ARG A NH2   1 
ATOM   2649  N  N     . TYR A 1 426  ? 129.021 121.527 116.965 1.00 22.85  ? 444  TYR A N     1 
ATOM   2650  C  CA    . TYR A 1 426  ? 129.861 122.557 116.364 1.00 22.85  ? 444  TYR A CA    1 
ATOM   2651  C  C     . TYR A 1 426  ? 129.160 123.906 116.368 1.00 22.85  ? 444  TYR A C     1 
ATOM   2652  O  O     . TYR A 1 426  ? 129.733 124.910 116.798 1.00 22.85  ? 444  TYR A O     1 
ATOM   2653  C  CB    . TYR A 1 426  ? 130.245 122.163 114.939 1.00 22.85  ? 444  TYR A CB    1 
ATOM   2654  C  CG    . TYR A 1 426  ? 130.739 123.318 114.097 1.00 22.85  ? 444  TYR A CG    1 
ATOM   2655  C  CD1   . TYR A 1 426  ? 131.915 123.974 114.409 1.00 22.85  ? 444  TYR A CD1   1 
ATOM   2656  C  CD2   . TYR A 1 426  ? 130.032 123.742 112.986 1.00 22.85  ? 444  TYR A CD2   1 
ATOM   2657  C  CE1   . TYR A 1 426  ? 132.370 125.024 113.642 1.00 22.85  ? 444  TYR A CE1   1 
ATOM   2658  C  CE2   . TYR A 1 426  ? 130.482 124.791 112.214 1.00 22.85  ? 444  TYR A CE2   1 
ATOM   2659  C  CZ    . TYR A 1 426  ? 131.651 125.427 112.548 1.00 22.85  ? 444  TYR A CZ    1 
ATOM   2660  O  OH    . TYR A 1 426  ? 132.105 126.472 111.785 1.00 22.85  ? 444  TYR A OH    1 
ATOM   2661  N  N     . LEU A 1 427  ? 127.909 123.944 115.902 1.00 24.30  ? 445  LEU A N     1 
ATOM   2662  C  CA    . LEU A 1 427  ? 127.176 125.205 115.839 1.00 24.30  ? 445  LEU A CA    1 
ATOM   2663  C  C     . LEU A 1 427  ? 126.952 125.782 117.228 1.00 24.30  ? 445  LEU A C     1 
ATOM   2664  O  O     . LEU A 1 427  ? 127.159 126.979 117.458 1.00 24.30  ? 445  LEU A O     1 
ATOM   2665  C  CB    . LEU A 1 427  ? 125.838 125.003 115.130 1.00 24.30  ? 445  LEU A CB    1 
ATOM   2666  C  CG    . LEU A 1 427  ? 125.864 124.765 113.625 1.00 24.30  ? 445  LEU A CG    1 
ATOM   2667  C  CD1   . LEU A 1 427  ? 124.449 124.745 113.087 1.00 24.30  ? 445  LEU A CD1   1 
ATOM   2668  C  CD2   . LEU A 1 427  ? 126.690 125.834 112.937 1.00 24.30  ? 445  LEU A CD2   1 
ATOM   2669  N  N     . ALA A 1 428  ? 126.528 124.939 118.171 1.00 26.82  ? 446  ALA A N     1 
ATOM   2670  C  CA    . ALA A 1 428  ? 126.247 125.406 119.522 1.00 26.82  ? 446  ALA A CA    1 
ATOM   2671  C  C     . ALA A 1 428  ? 127.503 125.944 120.189 1.00 26.82  ? 446  ALA A C     1 
ATOM   2672  O  O     . ALA A 1 428  ? 127.489 127.033 120.769 1.00 26.82  ? 446  ALA A O     1 
ATOM   2673  C  CB    . ALA A 1 428  ? 125.640 124.273 120.349 1.00 26.82  ? 446  ALA A CB    1 
ATOM   2674  N  N     . GLU A 1 429  ? 128.609 125.225 120.078 1.00 27.76  ? 447  GLU A N     1 
ATOM   2675  C  CA    . GLU A 1 429  ? 129.848 125.645 120.722 1.00 27.76  ? 447  GLU A CA    1 
ATOM   2676  C  C     . GLU A 1 429  ? 130.445 126.848 120.048 1.00 27.76  ? 447  GLU A C     1 
ATOM   2677  O  O     . GLU A 1 429  ? 131.024 127.704 120.706 1.00 27.76  ? 447  GLU A O     1 
ATOM   2678  C  CB    . GLU A 1 429  ? 130.860 124.510 120.702 1.00 27.76  ? 447  GLU A CB    1 
ATOM   2679  C  CG    . GLU A 1 429  ? 130.455 123.302 121.527 1.00 27.76  ? 447  GLU A CG    1 
ATOM   2680  C  CD    . GLU A 1 429  ? 131.332 122.097 121.258 1.00 27.76  ? 447  GLU A CD    1 
ATOM   2681  O  OE1   . GLU A 1 429  ? 132.097 122.126 120.272 1.00 27.76  ? 447  GLU A OE1   1 
ATOM   2682  O  OE2   . GLU A 1 429  ? 131.255 121.118 122.029 1.00 27.76  ? 447  GLU A OE2   1 
ATOM   2683  N  N     . ALA A 1 430  ? 130.318 126.923 118.734 1.00 24.13  ? 448  ALA A N     1 
ATOM   2684  C  CA    . ALA A 1 430  ? 130.812 128.091 118.016 1.00 24.13  ? 448  ALA A CA    1 
ATOM   2685  C  C     . ALA A 1 430  ? 130.018 129.338 118.378 1.00 24.13  ? 448  ALA A C     1 
ATOM   2686  O  O     . ALA A 1 430  ? 130.602 130.398 118.617 1.00 24.13  ? 448  ALA A O     1 
ATOM   2687  C  CB    . ALA A 1 430  ? 130.762 127.840 116.511 1.00 24.13  ? 448  ALA A CB    1 
ATOM   2688  N  N     . GLN A 1 431  ? 128.689 129.230 118.442 1.00 26.20  ? 449  GLN A N     1 
ATOM   2689  C  CA    . GLN A 1 431  ? 127.882 130.383 118.823 1.00 26.20  ? 449  GLN A CA    1 
ATOM   2690  C  C     . GLN A 1 431  ? 128.114 130.762 120.279 1.00 26.20  ? 449  GLN A C     1 
ATOM   2691  O  O     . GLN A 1 431  ? 128.169 131.951 120.616 1.00 26.20  ? 449  GLN A O     1 
ATOM   2692  C  CB    . GLN A 1 431  ? 126.402 130.100 118.573 1.00 26.20  ? 449  GLN A CB    1 
ATOM   2693  C  CG    . GLN A 1 431  ? 125.508 131.299 118.825 1.00 26.20  ? 449  GLN A CG    1 
ATOM   2694  C  CD    . GLN A 1 431  ? 125.860 132.477 117.937 1.00 26.20  ? 449  GLN A CD    1 
ATOM   2695  O  OE1   . GLN A 1 431  ? 126.159 132.309 116.756 1.00 26.20  ? 449  GLN A OE1   1 
ATOM   2696  N  NE2   . GLN A 1 431  ? 125.832 133.676 118.504 1.00 26.20  ? 449  GLN A NE2   1 
ATOM   2697  N  N     . GLY A 1 432  ? 128.247 129.768 121.158 1.00 26.04  ? 450  GLY A N     1 
ATOM   2698  C  CA    . GLY A 1 432  ? 128.521 130.062 122.552 1.00 26.04  ? 450  GLY A CA    1 
ATOM   2699  C  C     . GLY A 1 432  ? 129.863 130.733 122.744 1.00 26.04  ? 450  GLY A C     1 
ATOM   2700  O  O     . GLY A 1 432  ? 129.985 131.681 123.518 1.00 26.04  ? 450  GLY A O     1 
ATOM   2701  N  N     . THR A 1 433  ? 130.886 130.260 122.033 1.00 23.71  ? 451  THR A N     1 
ATOM   2702  C  CA    . THR A 1 433  ? 132.192 130.899 122.095 1.00 23.71  ? 451  THR A CA    1 
ATOM   2703  C  C     . THR A 1 433  ? 132.164 132.285 121.469 1.00 23.71  ? 451  THR A C     1 
ATOM   2704  O  O     . THR A 1 433  ? 132.852 133.188 121.947 1.00 23.71  ? 451  THR A O     1 
ATOM   2705  C  CB    . THR A 1 433  ? 133.231 130.020 121.402 1.00 23.71  ? 451  THR A CB    1 
ATOM   2706  O  OG1   . THR A 1 433  ? 133.214 128.714 121.989 1.00 23.71  ? 451  THR A OG1   1 
ATOM   2707  C  CG2   . THR A 1 433  ? 134.615 130.612 121.550 1.00 23.71  ? 451  THR A CG2   1 
ATOM   2708  N  N     . TYR A 1 434  ? 131.370 132.478 120.416 1.00 20.40  ? 452  TYR A N     1 
ATOM   2709  C  CA    . TYR A 1 434  ? 131.232 133.803 119.823 1.00 20.40  ? 452  TYR A CA    1 
ATOM   2710  C  C     . TYR A 1 434  ? 130.612 134.775 120.815 1.00 20.40  ? 452  TYR A C     1 
ATOM   2711  O  O     . TYR A 1 434  ? 131.096 135.896 120.989 1.00 20.40  ? 452  TYR A O     1 
ATOM   2712  C  CB    . TYR A 1 434  ? 130.395 133.709 118.546 1.00 20.40  ? 452  TYR A CB    1 
ATOM   2713  C  CG    . TYR A 1 434  ? 130.204 135.017 117.813 1.00 20.40  ? 452  TYR A CG    1 
ATOM   2714  C  CD1   . TYR A 1 434  ? 131.291 135.773 117.408 1.00 20.40  ? 452  TYR A CD1   1 
ATOM   2715  C  CD2   . TYR A 1 434  ? 128.934 135.480 117.504 1.00 20.40  ? 452  TYR A CD2   1 
ATOM   2716  C  CE1   . TYR A 1 434  ? 131.119 136.961 116.734 1.00 20.40  ? 452  TYR A CE1   1 
ATOM   2717  C  CE2   . TYR A 1 434  ? 128.755 136.666 116.827 1.00 20.40  ? 452  TYR A CE2   1 
ATOM   2718  C  CZ    . TYR A 1 434  ? 129.851 137.401 116.445 1.00 20.40  ? 452  TYR A CZ    1 
ATOM   2719  O  OH    . TYR A 1 434  ? 129.682 138.586 115.770 1.00 20.40  ? 452  TYR A OH    1 
ATOM   2720  N  N     . GLU A 1 435  ? 129.546 134.349 121.494 1.00 22.58  ? 453  GLU A N     1 
ATOM   2721  C  CA    . GLU A 1 435  ? 128.919 135.196 122.503 1.00 22.58  ? 453  GLU A CA    1 
ATOM   2722  C  C     . GLU A 1 435  ? 129.846 135.432 123.689 1.00 22.58  ? 453  GLU A C     1 
ATOM   2723  O  O     . GLU A 1 435  ? 129.913 136.545 124.219 1.00 22.58  ? 453  GLU A O     1 
ATOM   2724  C  CB    . GLU A 1 435  ? 127.602 134.574 122.962 1.00 22.58  ? 453  GLU A CB    1 
ATOM   2725  C  CG    . GLU A 1 435  ? 126.522 134.574 121.893 1.00 22.58  ? 453  GLU A CG    1 
ATOM   2726  C  CD    . GLU A 1 435  ? 125.266 133.842 122.325 1.00 22.58  ? 453  GLU A CD    1 
ATOM   2727  O  OE1   . GLU A 1 435  ? 125.335 133.051 123.289 1.00 22.58  ? 453  GLU A OE1   1 
ATOM   2728  O  OE2   . GLU A 1 435  ? 124.208 134.057 121.698 1.00 22.58  ? 453  GLU A OE2   1 
ATOM   2729  N  N     . GLU A 1 436  ? 130.569 134.397 124.120 1.00 22.00  ? 454  GLU A N     1 
ATOM   2730  C  CA    . GLU A 1 436  ? 131.485 134.532 125.247 1.00 22.00  ? 454  GLU A CA    1 
ATOM   2731  C  C     . GLU A 1 436  ? 132.626 135.482 124.921 1.00 22.00  ? 454  GLU A C     1 
ATOM   2732  O  O     . GLU A 1 436  ? 132.999 136.320 125.747 1.00 22.00  ? 454  GLU A O     1 
ATOM   2733  C  CB    . GLU A 1 436  ? 132.027 133.159 125.636 1.00 22.00  ? 454  GLU A CB    1 
ATOM   2734  C  CG    . GLU A 1 436  ? 133.152 133.193 126.647 1.00 22.00  ? 454  GLU A CG    1 
ATOM   2735  C  CD    . GLU A 1 436  ? 133.755 131.823 126.881 1.00 22.00  ? 454  GLU A CD    1 
ATOM   2736  O  OE1   . GLU A 1 436  ? 133.479 130.907 126.079 1.00 22.00  ? 454  GLU A OE1   1 
ATOM   2737  O  OE2   . GLU A 1 436  ? 134.502 131.663 127.869 1.00 22.00  ? 454  GLU A OE2   1 
ATOM   2738  N  N     . LEU A 1 437  ? 133.186 135.376 123.718 1.00 18.73  ? 455  LEU A N     1 
ATOM   2739  C  CA    . LEU A 1 437  ? 134.261 136.271 123.324 1.00 18.73  ? 455  LEU A CA    1 
ATOM   2740  C  C     . LEU A 1 437  ? 133.740 137.671 123.041 1.00 18.73  ? 455  LEU A C     1 
ATOM   2741  O  O     . LEU A 1 437  ? 134.465 138.644 123.242 1.00 18.73  ? 455  LEU A O     1 
ATOM   2742  C  CB    . LEU A 1 437  ? 134.995 135.708 122.109 1.00 18.73  ? 455  LEU A CB    1 
ATOM   2743  C  CG    . LEU A 1 437  ? 136.200 134.809 122.407 1.00 18.73  ? 455  LEU A CG    1 
ATOM   2744  C  CD1   . LEU A 1 437  ? 135.804 133.572 123.192 1.00 18.73  ? 455  LEU A CD1   1 
ATOM   2745  C  CD2   . LEU A 1 437  ? 136.919 134.425 121.126 1.00 18.73  ? 455  LEU A CD2   1 
ATOM   2746  N  N     . GLN A 1 438  ? 132.484 137.801 122.613 1.00 19.87  ? 456  GLN A N     1 
ATOM   2747  C  CA    . GLN A 1 438  ? 131.893 139.129 122.491 1.00 19.87  ? 456  GLN A CA    1 
ATOM   2748  C  C     . GLN A 1 438  ? 131.713 139.779 123.855 1.00 19.87  ? 456  GLN A C     1 
ATOM   2749  O  O     . GLN A 1 438  ? 131.972 140.973 124.014 1.00 19.87  ? 456  GLN A O     1 
ATOM   2750  C  CB    . GLN A 1 438  ? 130.558 139.049 121.760 1.00 19.87  ? 456  GLN A CB    1 
ATOM   2751  C  CG    . GLN A 1 438  ? 130.654 139.325 120.280 1.00 19.87  ? 456  GLN A CG    1 
ATOM   2752  C  CD    . GLN A 1 438  ? 129.295 139.501 119.649 1.00 19.87  ? 456  GLN A CD    1 
ATOM   2753  O  OE1   . GLN A 1 438  ? 128.288 139.034 120.180 1.00 19.87  ? 456  GLN A OE1   1 
ATOM   2754  N  NE2   . GLN A 1 438  ? 129.253 140.187 118.514 1.00 19.87  ? 456  GLN A NE2   1 
ATOM   2755  N  N     . ARG A 1 439  ? 131.263 139.011 124.849 1.00 19.12  ? 457  ARG A N     1 
ATOM   2756  C  CA    . ARG A 1 439  ? 131.176 139.541 126.206 1.00 19.12  ? 457  ARG A CA    1 
ATOM   2757  C  C     . ARG A 1 439  ? 132.552 139.903 126.740 1.00 19.12  ? 457  ARG A C     1 
ATOM   2758  O  O     . ARG A 1 439  ? 132.717 140.936 127.394 1.00 19.12  ? 457  ARG A O     1 
ATOM   2759  C  CB    . ARG A 1 439  ? 130.502 138.534 127.133 1.00 19.12  ? 457  ARG A CB    1 
ATOM   2760  C  CG    . ARG A 1 439  ? 129.046 138.285 126.829 1.00 19.12  ? 457  ARG A CG    1 
ATOM   2761  C  CD    . ARG A 1 439  ? 128.361 137.651 128.021 1.00 19.12  ? 457  ARG A CD    1 
ATOM   2762  N  NE    . ARG A 1 439  ? 128.946 136.363 128.370 1.00 19.12  ? 457  ARG A NE    1 
ATOM   2763  C  CZ    . ARG A 1 439  ? 128.389 135.192 128.097 1.00 19.12  ? 457  ARG A CZ    1 
ATOM   2764  N  NH1   . ARG A 1 439  ? 127.224 135.109 127.475 1.00 19.12  ? 457  ARG A NH1   1 
ATOM   2765  N  NH2   . ARG A 1 439  ? 129.015 134.075 128.459 1.00 19.12  ? 457  ARG A NH2   1 
ATOM   2766  N  N     . GLU A 1 440  ? 133.550 139.058 126.483 1.00 16.53  ? 458  GLU A N     1 
ATOM   2767  C  CA    . GLU A 1 440  ? 134.906 139.348 126.932 1.00 16.53  ? 458  GLU A CA    1 
ATOM   2768  C  C     . GLU A 1 440  ? 135.454 140.598 126.257 1.00 16.53  ? 458  GLU A C     1 
ATOM   2769  O  O     . GLU A 1 440  ? 136.112 141.424 126.899 1.00 16.53  ? 458  GLU A O     1 
ATOM   2770  C  CB    . GLU A 1 440  ? 135.801 138.140 126.665 1.00 16.53  ? 458  GLU A CB    1 
ATOM   2771  C  CG    . GLU A 1 440  ? 137.267 138.358 126.954 1.00 16.53  ? 458  GLU A CG    1 
ATOM   2772  C  CD    . GLU A 1 440  ? 138.087 137.098 126.754 1.00 16.53  ? 458  GLU A CD    1 
ATOM   2773  O  OE1   . GLU A 1 440  ? 137.515 135.993 126.855 1.00 16.53  ? 458  GLU A OE1   1 
ATOM   2774  O  OE2   . GLU A 1 440  ? 139.302 137.216 126.490 1.00 16.53  ? 458  GLU A OE2   1 
ATOM   2775  N  N     . MET A 1 441  ? 135.168 140.770 124.967 1.00 18.25  ? 459  MET A N     1 
ATOM   2776  C  CA    . MET A 1 441  ? 135.619 141.958 124.254 1.00 18.25  ? 459  MET A CA    1 
ATOM   2777  C  C     . MET A 1 441  ? 134.892 143.204 124.737 1.00 18.25  ? 459  MET A C     1 
ATOM   2778  O  O     . MET A 1 441  ? 135.500 144.269 124.870 1.00 18.25  ? 459  MET A O     1 
ATOM   2779  C  CB    . MET A 1 441  ? 135.422 141.768 122.753 1.00 18.25  ? 459  MET A CB    1 
ATOM   2780  C  CG    . MET A 1 441  ? 135.912 142.925 121.909 1.00 18.25  ? 459  MET A CG    1 
ATOM   2781  S  SD    . MET A 1 441  ? 135.744 142.584 120.151 1.00 18.25  ? 459  MET A SD    1 
ATOM   2782  C  CE    . MET A 1 441  ? 134.047 142.017 120.090 1.00 18.25  ? 459  MET A CE    1 
ATOM   2783  N  N     . LYS A 1 442  ? 133.590 143.094 125.005 1.00 18.47  ? 460  LYS A N     1 
ATOM   2784  C  CA    . LYS A 1 442  ? 132.848 144.234 125.530 1.00 18.47  ? 460  LYS A CA    1 
ATOM   2785  C  C     . LYS A 1 442  ? 133.344 144.617 126.913 1.00 18.47  ? 460  LYS A C     1 
ATOM   2786  O  O     . LYS A 1 442  ? 133.466 145.804 127.229 1.00 18.47  ? 460  LYS A O     1 
ATOM   2787  C  CB    . LYS A 1 442  ? 131.354 143.925 125.570 1.00 18.47  ? 460  LYS A CB    1 
ATOM   2788  C  CG    . LYS A 1 442  ? 130.510 145.118 125.967 1.00 18.47  ? 460  LYS A CG    1 
ATOM   2789  C  CD    . LYS A 1 442  ? 129.041 144.764 126.022 1.00 18.47  ? 460  LYS A CD    1 
ATOM   2790  C  CE    . LYS A 1 442  ? 128.221 145.940 126.510 1.00 18.47  ? 460  LYS A CE    1 
ATOM   2791  N  NZ    . LYS A 1 442  ? 126.776 145.602 126.611 1.00 18.47  ? 460  LYS A NZ    1 
ATOM   2792  N  N     . LYS A 1 443  ? 133.653 143.643 127.758 1.00 14.61  ? 461  LYS A N     1 
ATOM   2793  C  CA    . LYS A 1 443  ? 134.184 143.932 129.084 1.00 14.61  ? 461  LYS A CA    1 
ATOM   2794  C  C     . LYS A 1 443  ? 135.558 144.539 128.971 1.00 14.61  ? 461  LYS A C     1 
ATOM   2795  O  O     . LYS A 1 443  ? 135.917 145.392 129.760 1.00 14.61  ? 461  LYS A O     1 
ATOM   2796  C  CB    . LYS A 1 443  ? 134.232 142.676 129.924 1.00 14.61  ? 461  LYS A CB    1 
ATOM   2797  C  CG    . LYS A 1 443  ? 134.954 142.833 131.246 1.00 14.61  ? 461  LYS A CG    1 
ATOM   2798  C  CD    . LYS A 1 443  ? 135.419 141.483 131.766 1.00 14.61  ? 461  LYS A CD    1 
ATOM   2799  C  CE    . LYS A 1 443  ? 134.282 140.475 131.774 1.00 14.61  ? 461  LYS A CE    1 
ATOM   2800  N  NZ    . LYS A 1 443  ? 134.737 139.119 132.187 1.00 14.61  ? 461  LYS A NZ    1 
ATOM   2801  N  N     . SER A 1 444  ? 136.347 144.102 128.010 1.00 15.98  ? 462  SER A N     1 
ATOM   2802  C  CA    . SER A 1 444  ? 137.640 144.739 127.789 1.00 15.98  ? 462  SER A CA    1 
ATOM   2803  C  C     . SER A 1 444  ? 137.476 146.180 127.326 1.00 15.98  ? 462  SER A C     1 
ATOM   2804  O  O     . SER A 1 444  ? 138.248 147.059 127.719 1.00 15.98  ? 462  SER A O     1 
ATOM   2805  C  CB    . SER A 1 444  ? 138.447 143.941 126.771 1.00 15.98  ? 462  SER A CB    1 
ATOM   2806  O  OG    . SER A 1 444  ? 139.623 144.639 126.415 1.00 15.98  ? 462  SER A OG    1 
ATOM   2807  N  N     . LEU A 1 445  ? 136.475 146.442 126.486 1.00 17.81  ? 463  LEU A N     1 
ATOM   2808  C  CA    . LEU A 1 445  ? 136.213 147.808 126.041 1.00 17.81  ? 463  LEU A CA    1 
ATOM   2809  C  C     . LEU A 1 445  ? 135.747 148.687 127.195 1.00 17.81  ? 463  LEU A C     1 
ATOM   2810  O  O     . LEU A 1 445  ? 136.181 149.837 127.325 1.00 17.81  ? 463  LEU A O     1 
ATOM   2811  C  CB    . LEU A 1 445  ? 135.176 147.799 124.922 1.00 17.81  ? 463  LEU A CB    1 
ATOM   2812  C  CG    . LEU A 1 445  ? 135.627 147.196 123.595 1.00 17.81  ? 463  LEU A CG    1 
ATOM   2813  C  CD1   . LEU A 1 445  ? 134.456 147.103 122.641 1.00 17.81  ? 463  LEU A CD1   1 
ATOM   2814  C  CD2   . LEU A 1 445  ? 136.738 148.037 123.011 1.00 17.81  ? 463  LEU A CD2   1 
ATOM   2815  N  N     . MET A 1 446  ? 134.850 148.167 128.033 1.00 38.40  ? 464  MET A N     1 
ATOM   2816  C  CA    . MET A 1 446  ? 134.408 148.915 129.203 1.00 38.40  ? 464  MET A CA    1 
ATOM   2817  C  C     . MET A 1 446  ? 135.565 149.168 130.156 1.00 38.40  ? 464  MET A C     1 
ATOM   2818  O  O     . MET A 1 446  ? 135.653 150.240 130.761 1.00 38.40  ? 464  MET A O     1 
ATOM   2819  C  CB    . MET A 1 446  ? 133.280 148.173 129.917 1.00 38.40  ? 464  MET A CB    1 
ATOM   2820  C  CG    . MET A 1 446  ? 132.036 147.993 129.079 1.00 38.40  ? 464  MET A CG    1 
ATOM   2821  S  SD    . MET A 1 446  ? 130.618 147.432 130.034 1.00 38.40  ? 464  MET A SD    1 
ATOM   2822  C  CE    . MET A 1 446  ? 131.234 145.891 130.694 1.00 38.40  ? 464  MET A CE    1 
ATOM   2823  N  N     . ASP A 1 447  ? 136.458 148.191 130.313 1.00 20.63  ? 465  ASP A N     1 
ATOM   2824  C  CA    . ASP A 1 447  ? 137.629 148.397 131.154 1.00 20.63  ? 465  ASP A CA    1 
ATOM   2825  C  C     . ASP A 1 447  ? 138.557 149.446 130.558 1.00 20.63  ? 465  ASP A C     1 
ATOM   2826  O  O     . ASP A 1 447  ? 139.154 150.238 131.293 1.00 20.63  ? 465  ASP A O     1 
ATOM   2827  C  CB    . ASP A 1 447  ? 138.364 147.077 131.364 1.00 20.63  ? 465  ASP A CB    1 
ATOM   2828  C  CG    . ASP A 1 447  ? 137.550 146.076 132.159 1.00 20.63  ? 465  ASP A CG    1 
ATOM   2829  O  OD1   . ASP A 1 447  ? 136.366 146.359 132.440 1.00 20.63  ? 465  ASP A OD1   1 
ATOM   2830  O  OD2   . ASP A 1 447  ? 138.094 145.005 132.504 1.00 20.63  ? 465  ASP A OD2   1 
ATOM   2831  N  N     . LEU A 1 448  ? 138.690 149.469 129.231 1.00 21.67  ? 466  LEU A N     1 
ATOM   2832  C  CA    . LEU A 1 448  ? 139.473 150.516 128.582 1.00 21.67  ? 466  LEU A CA    1 
ATOM   2833  C  C     . LEU A 1 448  ? 138.856 151.887 128.823 1.00 21.67  ? 466  LEU A C     1 
ATOM   2834  O  O     . LEU A 1 448  ? 139.568 152.863 129.087 1.00 21.67  ? 466  LEU A O     1 
ATOM   2835  C  CB    . LEU A 1 448  ? 139.575 150.243 127.083 1.00 21.67  ? 466  LEU A CB    1 
ATOM   2836  C  CG    . LEU A 1 448  ? 140.450 149.100 126.580 1.00 21.67  ? 466  LEU A CG    1 
ATOM   2837  C  CD1   . LEU A 1 448  ? 140.193 148.878 125.104 1.00 21.67  ? 466  LEU A CD1   1 
ATOM   2838  C  CD2   . LEU A 1 448  ? 141.908 149.418 126.821 1.00 21.67  ? 466  LEU A CD2   1 
ATOM   2839  N  N     . ALA A 1 449  ? 137.530 151.975 128.733 1.00 22.96  ? 467  ALA A N     1 
ATOM   2840  C  CA    . ALA A 1 449  ? 136.843 153.230 129.014 1.00 22.96  ? 467  ALA A CA    1 
ATOM   2841  C  C     . ALA A 1 449  ? 137.070 153.664 130.456 1.00 22.96  ? 467  ALA A C     1 
ATOM   2842  O  O     . ALA A 1 449  ? 137.399 154.824 130.723 1.00 22.96  ? 467  ALA A O     1 
ATOM   2843  C  CB    . ALA A 1 449  ? 135.351 153.086 128.725 1.00 22.96  ? 467  ALA A CB    1 
ATOM   2844  N  N     . ASN A 1 450  ? 136.907 152.733 131.400 1.00 38.40  ? 468  ASN A N     1 
ATOM   2845  C  CA    . ASN A 1 450  ? 137.097 153.053 132.810 1.00 38.40  ? 468  ASN A CA    1 
ATOM   2846  C  C     . ASN A 1 450  ? 138.519 153.520 133.083 1.00 38.40  ? 468  ASN A C     1 
ATOM   2847  O  O     . ASN A 1 450  ? 138.729 154.496 133.810 1.00 38.40  ? 468  ASN A O     1 
ATOM   2848  C  CB    . ASN A 1 450  ? 136.758 151.839 133.670 1.00 38.40  ? 468  ASN A CB    1 
ATOM   2849  C  CG    . ASN A 1 450  ? 135.311 151.429 133.543 1.00 38.40  ? 468  ASN A CG    1 
ATOM   2850  O  OD1   . ASN A 1 450  ? 134.495 152.172 133.011 1.00 38.40  ? 468  ASN A OD1   1 
ATOM   2851  N  ND2   . ASN A 1 450  ? 134.983 150.243 134.038 1.00 38.40  ? 468  ASN A ND2   1 
ATOM   2852  N  N     . ASP A 1 451  ? 139.510 152.842 132.506 1.00 23.84  ? 469  ASP A N     1 
ATOM   2853  C  CA    . ASP A 1 451  ? 140.886 153.302 132.619 1.00 23.84  ? 469  ASP A CA    1 
ATOM   2854  C  C     . ASP A 1 451  ? 141.136 154.580 131.835 1.00 23.84  ? 469  ASP A C     1 
ATOM   2855  O  O     . ASP A 1 451  ? 142.196 155.191 132.006 1.00 23.84  ? 469  ASP A O     1 
ATOM   2856  C  CB    . ASP A 1 451  ? 141.851 152.217 132.143 1.00 23.84  ? 469  ASP A CB    1 
ATOM   2857  C  CG    . ASP A 1 451  ? 141.663 150.908 132.878 1.00 23.84  ? 469  ASP A CG    1 
ATOM   2858  O  OD1   . ASP A 1 451  ? 140.727 150.813 133.699 1.00 23.84  ? 469  ASP A OD1   1 
ATOM   2859  O  OD2   . ASP A 1 451  ? 142.452 149.970 132.633 1.00 23.84  ? 469  ASP A OD2   1 
ATOM   2860  N  N     . ALA A 1 452  ? 140.199 154.990 130.982 1.00 26.19  ? 470  ALA A N     1 
ATOM   2861  C  CA    . ALA A 1 452  ? 140.342 156.225 130.226 1.00 26.19  ? 470  ALA A CA    1 
ATOM   2862  C  C     . ALA A 1 452  ? 139.797 157.441 130.962 1.00 26.19  ? 470  ALA A C     1 
ATOM   2863  O  O     . ALA A 1 452  ? 140.247 158.560 130.696 1.00 26.19  ? 470  ALA A O     1 
ATOM   2864  C  CB    . ALA A 1 452  ? 139.642 156.096 128.873 1.00 26.19  ? 470  ALA A CB    1 
ATOM   2865  N  N     . CYS A 1 453  ? 138.847 157.275 131.873 1.00 38.40  ? 471  CYS A N     1 
ATOM   2866  C  CA    . CYS A 1 453  ? 138.358 158.415 132.629 1.00 38.40  ? 471  CYS A CA    1 
ATOM   2867  C  C     . CYS A 1 453  ? 139.473 159.058 133.427 1.00 38.40  ? 471  CYS A C     1 
ATOM   2868  O  O     . CYS A 1 453  ? 139.591 160.270 133.485 1.00 38.40  ? 471  CYS A O     1 
ATOM   2869  C  CB    . CYS A 1 453  ? 137.253 157.977 133.565 1.00 38.40  ? 471  CYS A CB    1 
ATOM   2870  S  SG    . CYS A 1 453  ? 135.918 157.119 132.741 1.00 38.40  ? 471  CYS A SG    1 
ATOM   2871  N  N     . GLN A 1 454  ? 140.310 158.248 134.028 1.00 25.81  ? 472  GLN A N     1 
ATOM   2872  C  CA    . GLN A 1 454  ? 141.356 158.767 134.895 1.00 25.81  ? 472  GLN A CA    1 
ATOM   2873  C  C     . GLN A 1 454  ? 142.260 159.775 134.199 1.00 25.81  ? 472  GLN A C     1 
ATOM   2874  O  O     . GLN A 1 454  ? 143.044 160.444 134.879 1.00 25.81  ? 472  GLN A O     1 
ATOM   2875  C  CB    . GLN A 1 454  ? 142.178 157.602 135.444 1.00 25.81  ? 472  GLN A CB    1 
ATOM   2876  C  CG    . GLN A 1 454  ? 141.332 156.552 136.145 1.00 25.81  ? 472  GLN A CG    1 
ATOM   2877  C  CD    . GLN A 1 454  ? 142.069 155.248 136.349 1.00 25.81  ? 472  GLN A CD    1 
ATOM   2878  O  OE1   . GLN A 1 454  ? 143.293 155.191 136.251 1.00 25.81  ? 472  GLN A OE1   1 
ATOM   2879  N  NE2   . GLN A 1 454  ? 141.323 154.185 136.627 1.00 25.81  ? 472  GLN A NE2   1 
ATOM   2880  N  N     . LEU A 1 455  ? 142.176 159.900 132.872 1.00 26.56  ? 473  LEU A N     1 
ATOM   2881  C  CA    . LEU A 1 455  ? 142.841 161.002 132.186 1.00 26.56  ? 473  LEU A CA    1 
ATOM   2882  C  C     . LEU A 1 455  ? 142.204 162.343 132.518 1.00 26.56  ? 473  LEU A C     1 
ATOM   2883  O  O     . LEU A 1 455  ? 142.842 163.384 132.330 1.00 26.56  ? 473  LEU A O     1 
ATOM   2884  C  CB    . LEU A 1 455  ? 142.818 160.786 130.672 1.00 26.56  ? 473  LEU A CB    1 
ATOM   2885  C  CG    . LEU A 1 455  ? 143.779 159.772 130.047 1.00 26.56  ? 473  LEU A CG    1 
ATOM   2886  C  CD1   . LEU A 1 455  ? 145.199 160.044 130.505 1.00 26.56  ? 473  LEU A CD1   1 
ATOM   2887  C  CD2   . LEU A 1 455  ? 143.379 158.337 130.351 1.00 26.56  ? 473  LEU A CD2   1 
ATOM   2888  N  N     . LEU A 1 456  ? 140.955 162.341 132.990 1.00 24.36  ? 474  LEU A N     1 
ATOM   2889  C  CA    . LEU A 1 456  ? 140.306 163.587 133.380 1.00 24.36  ? 474  LEU A CA    1 
ATOM   2890  C  C     . LEU A 1 456  ? 141.014 164.228 134.563 1.00 24.36  ? 474  LEU A C     1 
ATOM   2891  O  O     . LEU A 1 456  ? 141.205 165.449 134.593 1.00 24.36  ? 474  LEU A O     1 
ATOM   2892  C  CB    . LEU A 1 456  ? 138.836 163.332 133.709 1.00 24.36  ? 474  LEU A CB    1 
ATOM   2893  C  CG    . LEU A 1 456  ? 138.026 164.511 134.241 1.00 24.36  ? 474  LEU A CG    1 
ATOM   2894  C  CD1   . LEU A 1 456  ? 138.122 165.694 133.297 1.00 24.36  ? 474  LEU A CD1   1 
ATOM   2895  C  CD2   . LEU A 1 456  ? 136.580 164.105 134.441 1.00 24.36  ? 474  LEU A CD2   1 
ATOM   2896  N  N     . SER A 1 457  ? 141.408 163.421 135.547 1.00 28.69  ? 475  SER A N     1 
ATOM   2897  C  CA    . SER A 1 457  ? 142.101 163.924 136.725 1.00 28.69  ? 475  SER A CA    1 
ATOM   2898  C  C     . SER A 1 457  ? 143.377 164.648 136.321 1.00 28.69  ? 475  SER A C     1 
ATOM   2899  O  O     . SER A 1 457  ? 144.319 164.027 135.821 1.00 28.69  ? 475  SER A O     1 
ATOM   2900  C  CB    . SER A 1 457  ? 142.416 162.780 137.689 1.00 28.69  ? 475  SER A CB    1 
ATOM   2901  O  OG    . SER A 1 457  ? 141.234 162.101 138.075 1.00 28.69  ? 475  SER A OG    1 
ATOM   2902  N  N     . GLY A 1 458  ? 143.414 165.959 136.534 1.00 34.06  ? 476  GLY A N     1 
ATOM   2903  C  CA    . GLY A 1 458  ? 144.535 166.759 136.091 1.00 34.06  ? 476  GLY A CA    1 
ATOM   2904  C  C     . GLY A 1 458  ? 144.529 167.095 134.620 1.00 34.06  ? 476  GLY A C     1 
ATOM   2905  O  O     . GLY A 1 458  ? 145.533 167.612 134.117 1.00 34.06  ? 476  GLY A O     1 
ATOM   2906  N  N     . GLU A 1 459  ? 143.428 166.820 133.917 1.00 33.85  ? 477  GLU A N     1 
ATOM   2907  C  CA    . GLU A 1 459  ? 143.305 167.079 132.482 1.00 33.85  ? 477  GLU A CA    1 
ATOM   2908  C  C     . GLU A 1 459  ? 144.435 166.411 131.700 1.00 33.85  ? 477  GLU A C     1 
ATOM   2909  O  O     . GLU A 1 459  ? 145.076 167.020 130.841 1.00 33.85  ? 477  GLU A O     1 
ATOM   2910  C  CB    . GLU A 1 459  ? 143.254 168.581 132.194 1.00 33.85  ? 477  GLU A CB    1 
ATOM   2911  C  CG    . GLU A 1 459  ? 142.095 169.299 132.858 1.00 33.85  ? 477  GLU A CG    1 
ATOM   2912  C  CD    . GLU A 1 459  ? 142.049 170.770 132.502 1.00 33.85  ? 477  GLU A CD    1 
ATOM   2913  O  OE1   . GLU A 1 459  ? 142.803 171.186 131.598 1.00 33.85  ? 477  GLU A OE1   1 
ATOM   2914  O  OE2   . GLU A 1 459  ? 141.261 171.510 133.128 1.00 33.85  ? 477  GLU A OE2   1 
ATOM   2915  N  N     . ARG A 1 460  ? 144.683 165.140 132.013 1.00 31.33  ? 478  ARG A N     1 
ATOM   2916  C  CA    . ARG A 1 460  ? 145.691 164.376 131.292 1.00 31.33  ? 478  ARG A CA    1 
ATOM   2917  C  C     . ARG A 1 460  ? 145.216 163.926 129.919 1.00 31.33  ? 478  ARG A C     1 
ATOM   2918  O  O     . ARG A 1 460  ? 146.042 163.492 129.110 1.00 31.33  ? 478  ARG A O     1 
ATOM   2919  C  CB    . ARG A 1 460  ? 146.121 163.153 132.108 1.00 31.33  ? 478  ARG A CB    1 
ATOM   2920  C  CG    . ARG A 1 460  ? 146.608 163.472 133.511 1.00 31.33  ? 478  ARG A CG    1 
ATOM   2921  C  CD    . ARG A 1 460  ? 147.464 162.345 134.071 1.00 31.33  ? 478  ARG A CD    1 
ATOM   2922  N  NE    . ARG A 1 460  ? 146.815 161.044 133.971 1.00 31.33  ? 478  ARG A NE    1 
ATOM   2923  C  CZ    . ARG A 1 460  ? 146.096 160.487 134.936 1.00 31.33  ? 478  ARG A CZ    1 
ATOM   2924  N  NH1   . ARG A 1 460  ? 145.895 161.100 136.090 1.00 31.33  ? 478  ARG A NH1   1 
ATOM   2925  N  NH2   . ARG A 1 460  ? 145.567 159.283 134.738 1.00 31.33  ? 478  ARG A NH2   1 
ATOM   2926  N  N     . TYR A 1 461  ? 143.914 164.012 129.639 1.00 28.50  ? 479  TYR A N     1 
ATOM   2927  C  CA    . TYR A 1 461  ? 143.409 163.614 128.331 1.00 28.50  ? 479  TYR A CA    1 
ATOM   2928  C  C     . TYR A 1 461  ? 143.924 164.505 127.212 1.00 28.50  ? 479  TYR A C     1 
ATOM   2929  O  O     . TYR A 1 461  ? 143.946 164.073 126.056 1.00 28.50  ? 479  TYR A O     1 
ATOM   2930  C  CB    . TYR A 1 461  ? 141.881 163.613 128.327 1.00 28.50  ? 479  TYR A CB    1 
ATOM   2931  C  CG    . TYR A 1 461  ? 141.226 164.951 128.615 1.00 28.50  ? 479  TYR A CG    1 
ATOM   2932  C  CD1   . TYR A 1 461  ? 141.053 165.897 127.612 1.00 28.50  ? 479  TYR A CD1   1 
ATOM   2933  C  CD2   . TYR A 1 461  ? 140.756 165.253 129.885 1.00 28.50  ? 479  TYR A CD2   1 
ATOM   2934  C  CE1   . TYR A 1 461  ? 140.450 167.112 127.872 1.00 28.50  ? 479  TYR A CE1   1 
ATOM   2935  C  CE2   . TYR A 1 461  ? 140.150 166.465 130.153 1.00 28.50  ? 479  TYR A CE2   1 
ATOM   2936  C  CZ    . TYR A 1 461  ? 139.999 167.389 129.144 1.00 28.50  ? 479  TYR A CZ    1 
ATOM   2937  O  OH    . TYR A 1 461  ? 139.396 168.597 129.410 1.00 28.50  ? 479  TYR A OH    1 
ATOM   2938  N  N     . LYS A 1 462  ? 144.338 165.732 127.523 1.00 29.53  ? 480  LYS A N     1 
ATOM   2939  C  CA    . LYS A 1 462  ? 144.773 166.660 126.488 1.00 29.53  ? 480  LYS A CA    1 
ATOM   2940  C  C     . LYS A 1 462  ? 146.063 166.219 125.808 1.00 29.53  ? 480  LYS A C     1 
ATOM   2941  O  O     . LYS A 1 462  ? 146.415 166.780 124.766 1.00 29.53  ? 480  LYS A O     1 
ATOM   2942  C  CB    . LYS A 1 462  ? 144.941 168.058 127.086 1.00 29.53  ? 480  LYS A CB    1 
ATOM   2943  C  CG    . LYS A 1 462  ? 144.829 169.186 126.075 1.00 29.53  ? 480  LYS A CG    1 
ATOM   2944  C  CD    . LYS A 1 462  ? 144.637 170.526 126.765 1.00 29.53  ? 480  LYS A CD    1 
ATOM   2945  C  CE    . LYS A 1 462  ? 143.375 170.533 127.614 1.00 29.53  ? 480  LYS A CE    1 
ATOM   2946  N  NZ    . LYS A 1 462  ? 143.181 171.837 128.306 1.00 29.53  ? 480  LYS A NZ    1 
ATOM   2947  N  N     . GLU A 1 463  ? 146.765 165.231 126.361 1.00 29.33  ? 481  GLU A N     1 
ATOM   2948  C  CA    . GLU A 1 463  ? 147.982 164.710 125.761 1.00 29.33  ? 481  GLU A CA    1 
ATOM   2949  C  C     . GLU A 1 463  ? 147.837 163.290 125.234 1.00 29.33  ? 481  GLU A C     1 
ATOM   2950  O  O     . GLU A 1 463  ? 148.759 162.796 124.575 1.00 29.33  ? 481  GLU A O     1 
ATOM   2951  C  CB    . GLU A 1 463  ? 149.135 164.763 126.773 1.00 29.33  ? 481  GLU A CB    1 
ATOM   2952  C  CG    . GLU A 1 463  ? 149.352 166.142 127.369 1.00 29.33  ? 481  GLU A CG    1 
ATOM   2953  C  CD    . GLU A 1 463  ? 149.586 167.203 126.311 1.00 29.33  ? 481  GLU A CD    1 
ATOM   2954  O  OE1   . GLU A 1 463  ? 150.273 166.908 125.310 1.00 29.33  ? 481  GLU A OE1   1 
ATOM   2955  O  OE2   . GLU A 1 463  ? 149.077 168.331 126.477 1.00 29.33  ? 481  GLU A OE2   1 
ATOM   2956  N  N     . ASP A 1 464  ? 146.723 162.625 125.507 1.00 19.87  ? 482  ASP A N     1 
ATOM   2957  C  CA    . ASP A 1 464  ? 146.509 161.285 124.977 1.00 19.87  ? 482  ASP A CA    1 
ATOM   2958  C  C     . ASP A 1 464  ? 146.337 161.365 123.464 1.00 19.87  ? 482  ASP A C     1 
ATOM   2959  O  O     . ASP A 1 464  ? 145.481 162.114 122.982 1.00 19.87  ? 482  ASP A O     1 
ATOM   2960  C  CB    . ASP A 1 464  ? 145.283 160.648 125.626 1.00 19.87  ? 482  ASP A CB    1 
ATOM   2961  C  CG    . ASP A 1 464  ? 145.213 159.148 125.407 1.00 19.87  ? 482  ASP A CG    1 
ATOM   2962  O  OD1   . ASP A 1 464  ? 145.436 158.691 124.269 1.00 19.87  ? 482  ASP A OD1   1 
ATOM   2963  O  OD2   . ASP A 1 464  ? 144.934 158.419 126.381 1.00 19.87  ? 482  ASP A OD2   1 
ATOM   2964  N  N     . PRO A 1 465  ? 147.126 160.620 122.687 1.00 15.25  ? 483  PRO A N     1 
ATOM   2965  C  CA    . PRO A 1 465  ? 147.033 160.730 121.223 1.00 15.25  ? 483  PRO A CA    1 
ATOM   2966  C  C     . PRO A 1 465  ? 145.713 160.253 120.649 1.00 15.25  ? 483  PRO A C     1 
ATOM   2967  O  O     . PRO A 1 465  ? 145.441 160.513 119.471 1.00 15.25  ? 483  PRO A O     1 
ATOM   2968  C  CB    . PRO A 1 465  ? 148.200 159.862 120.731 1.00 15.25  ? 483  PRO A CB    1 
ATOM   2969  C  CG    . PRO A 1 465  ? 149.132 159.773 121.894 1.00 15.25  ? 483  PRO A CG    1 
ATOM   2970  C  CD    . PRO A 1 465  ? 148.255 159.775 123.106 1.00 15.25  ? 483  PRO A CD    1 
ATOM   2971  N  N     . TRP A 1 466  ? 144.885 159.560 121.428 1.00 18.09  ? 484  TRP A N     1 
ATOM   2972  C  CA    . TRP A 1 466  ? 143.640 159.005 120.916 1.00 18.09  ? 484  TRP A CA    1 
ATOM   2973  C  C     . TRP A 1 466  ? 142.386 159.683 121.444 1.00 18.09  ? 484  TRP A C     1 
ATOM   2974  O  O     . TRP A 1 466  ? 141.414 159.804 120.698 1.00 18.09  ? 484  TRP A O     1 
ATOM   2975  C  CB    . TRP A 1 466  ? 143.557 157.508 121.235 1.00 18.09  ? 484  TRP A CB    1 
ATOM   2976  C  CG    . TRP A 1 466  ? 144.557 156.682 120.497 1.00 18.09  ? 484  TRP A CG    1 
ATOM   2977  C  CD1   . TRP A 1 466  ? 144.370 156.038 119.312 1.00 18.09  ? 484  TRP A CD1   1 
ATOM   2978  C  CD2   . TRP A 1 466  ? 145.904 156.407 120.895 1.00 18.09  ? 484  TRP A CD2   1 
ATOM   2979  N  NE1   . TRP A 1 466  ? 145.518 155.378 118.945 1.00 18.09  ? 484  TRP A NE1   1 
ATOM   2980  C  CE2   . TRP A 1 466  ? 146.475 155.590 119.901 1.00 18.09  ? 484  TRP A CE2   1 
ATOM   2981  C  CE3   . TRP A 1 466  ? 146.683 156.774 121.995 1.00 18.09  ? 484  TRP A CE3   1 
ATOM   2982  C  CZ2   . TRP A 1 466  ? 147.787 155.132 119.975 1.00 18.09  ? 484  TRP A CZ2   1 
ATOM   2983  C  CZ3   . TRP A 1 466  ? 147.985 156.320 122.066 1.00 18.09  ? 484  TRP A CZ3   1 
ATOM   2984  C  CH2   . TRP A 1 466  ? 148.524 155.509 121.062 1.00 18.09  ? 484  TRP A CH2   1 
ATOM   2985  N  N     . LEU A 1 467  ? 142.371 160.123 122.702 1.00 15.02  ? 485  LEU A N     1 
ATOM   2986  C  CA    . LEU A 1 467  ? 141.165 160.663 123.320 1.00 15.02  ? 485  LEU A CA    1 
ATOM   2987  C  C     . LEU A 1 467  ? 141.218 162.175 123.492 1.00 15.02  ? 485  LEU A C     1 
ATOM   2988  O  O     . LEU A 1 467  ? 140.431 162.733 124.262 1.00 15.02  ? 485  LEU A O     1 
ATOM   2989  C  CB    . LEU A 1 467  ? 140.919 159.989 124.668 1.00 15.02  ? 485  LEU A CB    1 
ATOM   2990  C  CG    . LEU A 1 467  ? 140.732 158.478 124.620 1.00 15.02  ? 485  LEU A CG    1 
ATOM   2991  C  CD1   . LEU A 1 467  ? 140.741 157.901 126.015 1.00 15.02  ? 485  LEU A CD1   1 
ATOM   2992  C  CD2   . LEU A 1 467  ? 139.437 158.148 123.916 1.00 15.02  ? 485  LEU A CD2   1 
ATOM   2993  N  N     . TRP A 1 468  ? 142.131 162.850 122.794 1.00 20.08  ? 486  TRP A N     1 
ATOM   2994  C  CA    . TRP A 1 468  ? 142.298 164.285 122.991 1.00 20.08  ? 486  TRP A CA    1 
ATOM   2995  C  C     . TRP A 1 468  ? 141.121 165.080 122.442 1.00 20.08  ? 486  TRP A C     1 
ATOM   2996  O  O     . TRP A 1 468  ? 140.792 166.143 122.979 1.00 20.08  ? 486  TRP A O     1 
ATOM   2997  C  CB    . TRP A 1 468  ? 143.596 164.756 122.337 1.00 20.08  ? 486  TRP A CB    1 
ATOM   2998  C  CG    . TRP A 1 468  ? 143.531 164.781 120.844 1.00 20.08  ? 486  TRP A CG    1 
ATOM   2999  C  CD1   . TRP A 1 468  ? 143.865 163.773 119.990 1.00 20.08  ? 486  TRP A CD1   1 
ATOM   3000  C  CD2   . TRP A 1 468  ? 143.098 165.873 120.027 1.00 20.08  ? 486  TRP A CD2   1 
ATOM   3001  N  NE1   . TRP A 1 468  ? 143.669 164.170 118.690 1.00 20.08  ? 486  TRP A NE1   1 
ATOM   3002  C  CE2   . TRP A 1 468  ? 143.197 165.456 118.687 1.00 20.08  ? 486  TRP A CE2   1 
ATOM   3003  C  CE3   . TRP A 1 468  ? 142.635 167.163 120.299 1.00 20.08  ? 486  TRP A CE3   1 
ATOM   3004  C  CZ2   . TRP A 1 468  ? 142.853 166.282 117.623 1.00 20.08  ? 486  TRP A CZ2   1 
ATOM   3005  C  CZ3   . TRP A 1 468  ? 142.294 167.981 119.242 1.00 20.08  ? 486  TRP A CZ3   1 
ATOM   3006  C  CH2   . TRP A 1 468  ? 142.404 167.539 117.920 1.00 20.08  ? 486  TRP A CH2   1 
ATOM   3007  N  N     . ASP A 1 469  ? 140.478 164.593 121.384 1.00 20.69  ? 487  ASP A N     1 
ATOM   3008  C  CA    . ASP A 1 469  ? 139.463 165.358 120.673 1.00 20.69  ? 487  ASP A CA    1 
ATOM   3009  C  C     . ASP A 1 469  ? 138.041 164.974 121.061 1.00 20.69  ? 487  ASP A C     1 
ATOM   3010  O  O     . ASP A 1 469  ? 137.096 165.381 120.380 1.00 20.69  ? 487  ASP A O     1 
ATOM   3011  C  CB    . ASP A 1 469  ? 139.651 165.206 119.161 1.00 20.69  ? 487  ASP A CB    1 
ATOM   3012  C  CG    . ASP A 1 469  ? 139.648 163.757 118.711 1.00 20.69  ? 487  ASP A CG    1 
ATOM   3013  O  OD1   . ASP A 1 469  ? 139.463 162.861 119.560 1.00 20.69  ? 487  ASP A OD1   1 
ATOM   3014  O  OD2   . ASP A 1 469  ? 139.835 163.513 117.501 1.00 20.69  ? 487  ASP A OD2   1 
ATOM   3015  N  N     . LEU A 1 470  ? 137.865 164.208 122.132 1.00 21.97  ? 488  LEU A N     1 
ATOM   3016  C  CA    . LEU A 1 470  ? 136.532 163.825 122.575 1.00 21.97  ? 488  LEU A CA    1 
ATOM   3017  C  C     . LEU A 1 470  ? 135.924 164.956 123.402 1.00 21.97  ? 488  LEU A C     1 
ATOM   3018  O  O     . LEU A 1 470  ? 136.487 166.048 123.522 1.00 21.97  ? 488  LEU A O     1 
ATOM   3019  C  CB    . LEU A 1 470  ? 136.585 162.516 123.355 1.00 21.97  ? 488  LEU A CB    1 
ATOM   3020  C  CG    . LEU A 1 470  ? 136.195 161.264 122.575 1.00 21.97  ? 488  LEU A CG    1 
ATOM   3021  C  CD1   . LEU A 1 470  ? 137.083 161.110 121.359 1.00 21.97  ? 488  LEU A CD1   1 
ATOM   3022  C  CD2   . LEU A 1 470  ? 136.278 160.037 123.459 1.00 21.97  ? 488  LEU A CD2   1 
ATOM   3023  N  N     . GLU A 1 471  ? 134.751 164.675 123.975 1.00 30.87  ? 489  GLU A N     1 
ATOM   3024  C  CA    . GLU A 1 471  ? 134.069 165.649 124.825 1.00 30.87  ? 489  GLU A CA    1 
ATOM   3025  C  C     . GLU A 1 471  ? 134.203 165.256 126.278 1.00 30.87  ? 489  GLU A C     1 
ATOM   3026  O  O     . GLU A 1 471  ? 133.590 164.289 126.717 1.00 30.87  ? 489  GLU A O     1 
ATOM   3027  C  CB    . GLU A 1 471  ? 132.595 165.713 124.473 1.00 30.87  ? 489  GLU A CB    1 
ATOM   3028  C  CG    . GLU A 1 471  ? 132.317 166.016 123.015 1.00 30.87  ? 489  GLU A CG    1 
ATOM   3029  C  CD    . GLU A 1 471  ? 130.839 165.953 122.691 1.00 30.87  ? 489  GLU A CD    1 
ATOM   3030  O  OE1   . GLU A 1 471  ? 130.051 165.601 123.594 1.00 30.87  ? 489  GLU A OE1   1 
ATOM   3031  O  OE2   . GLU A 1 471  ? 130.468 166.253 121.537 1.00 30.87  ? 489  GLU A OE2   1 
ATOM   3032  N  N     . TRP A 1 472  ? 134.988 166.001 127.035 1.00 23.91  ? 490  TRP A N     1 
ATOM   3033  C  CA    . TRP A 1 472  ? 135.240 165.708 128.440 1.00 23.91  ? 490  TRP A CA    1 
ATOM   3034  C  C     . TRP A 1 472  ? 134.477 166.628 129.387 1.00 23.91  ? 490  TRP A C     1 
ATOM   3035  O  O     . TRP A 1 472  ? 134.760 166.628 130.588 1.00 23.91  ? 490  TRP A O     1 
ATOM   3036  C  CB    . TRP A 1 472  ? 136.740 165.791 128.737 1.00 23.91  ? 490  TRP A CB    1 
ATOM   3037  C  CG    . TRP A 1 472  ? 137.550 164.713 128.085 1.00 23.91  ? 490  TRP A CG    1 
ATOM   3038  C  CD1   . TRP A 1 472  ? 138.048 164.718 126.818 1.00 23.91  ? 490  TRP A CD1   1 
ATOM   3039  C  CD2   . TRP A 1 472  ? 137.960 163.473 128.672 1.00 23.91  ? 490  TRP A CD2   1 
ATOM   3040  N  NE1   . TRP A 1 472  ? 138.740 163.557 126.576 1.00 23.91  ? 490  TRP A NE1   1 
ATOM   3041  C  CE2   . TRP A 1 472  ? 138.699 162.775 127.699 1.00 23.91  ? 490  TRP A CE2   1 
ATOM   3042  C  CE3   . TRP A 1 472  ? 137.769 162.884 129.923 1.00 23.91  ? 490  TRP A CE3   1 
ATOM   3043  C  CZ2   . TRP A 1 472  ? 139.248 161.519 127.940 1.00 23.91  ? 490  TRP A CZ2   1 
ATOM   3044  C  CZ3   . TRP A 1 472  ? 138.314 161.640 130.160 1.00 23.91  ? 490  TRP A CZ3   1 
ATOM   3045  C  CH2   . TRP A 1 472  ? 139.046 160.971 129.174 1.00 23.91  ? 490  TRP A CH2   1 
ATOM   3046  N  N     . ASP A 1 473  ? 133.524 167.407 128.879 1.00 26.93  ? 491  ASP A N     1 
ATOM   3047  C  CA    . ASP A 1 473  ? 132.883 168.437 129.687 1.00 26.93  ? 491  ASP A CA    1 
ATOM   3048  C  C     . ASP A 1 473  ? 132.130 167.833 130.868 1.00 26.93  ? 491  ASP A C     1 
ATOM   3049  O  O     . ASP A 1 473  ? 131.635 166.705 130.813 1.00 26.93  ? 491  ASP A O     1 
ATOM   3050  C  CB    . ASP A 1 473  ? 131.923 169.265 128.832 1.00 26.93  ? 491  ASP A CB    1 
ATOM   3051  C  CG    . ASP A 1 473  ? 132.645 170.249 127.934 1.00 26.93  ? 491  ASP A CG    1 
ATOM   3052  O  OD1   . ASP A 1 473  ? 133.894 170.229 127.911 1.00 26.93  ? 491  ASP A OD1   1 
ATOM   3053  O  OD2   . ASP A 1 473  ? 131.965 171.046 127.254 1.00 26.93  ? 491  ASP A OD2   1 
ATOM   3054  N  N     . LEU A 1 474  ? 132.050 168.610 131.946 1.00 26.68  ? 492  LEU A N     1 
ATOM   3055  C  CA    . LEU A 1 474  ? 131.393 168.225 133.184 1.00 26.68  ? 492  LEU A CA    1 
ATOM   3056  C  C     . LEU A 1 474  ? 130.150 169.073 133.423 1.00 26.68  ? 492  LEU A C     1 
ATOM   3057  O  O     . LEU A 1 474  ? 130.040 170.206 132.948 1.00 26.68  ? 492  LEU A O     1 
ATOM   3058  C  CB    . LEU A 1 474  ? 132.342 168.369 134.378 1.00 26.68  ? 492  LEU A CB    1 
ATOM   3059  C  CG    . LEU A 1 474  ? 133.432 167.313 134.517 1.00 26.68  ? 492  LEU A CG    1 
ATOM   3060  C  CD1   . LEU A 1 474  ? 134.253 167.554 135.771 1.00 26.68  ? 492  LEU A CD1   1 
ATOM   3061  C  CD2   . LEU A 1 474  ? 132.789 165.953 134.554 1.00 26.68  ? 492  LEU A CD2   1 
ATOM   3062  N  N     . GLN A 1 475  ? 129.214 168.507 134.179 1.00 27.19  ? 493  GLN A N     1 
ATOM   3063  C  CA    . GLN A 1 475  ? 127.998 169.200 134.571 1.00 27.19  ? 493  GLN A CA    1 
ATOM   3064  C  C     . GLN A 1 475  ? 127.905 169.240 136.088 1.00 27.19  ? 493  GLN A C     1 
ATOM   3065  O  O     . GLN A 1 475  ? 128.412 168.356 136.782 1.00 27.19  ? 493  GLN A O     1 
ATOM   3066  C  CB    . GLN A 1 475  ? 126.751 168.527 133.997 1.00 27.19  ? 493  GLN A CB    1 
ATOM   3067  C  CG    . GLN A 1 475  ? 126.638 168.612 132.492 1.00 27.19  ? 493  GLN A CG    1 
ATOM   3068  C  CD    . GLN A 1 475  ? 125.367 167.975 131.977 1.00 27.19  ? 493  GLN A CD    1 
ATOM   3069  O  OE1   . GLN A 1 475  ? 124.733 167.180 132.670 1.00 27.19  ? 493  GLN A OE1   1 
ATOM   3070  N  NE2   . GLN A 1 475  ? 124.982 168.326 130.756 1.00 27.19  ? 493  GLN A NE2   1 
ATOM   3071  N  N     . GLU A 1 476  ? 127.258 170.280 136.596 1.00 28.12  ? 494  GLU A N     1 
ATOM   3072  C  CA    . GLU A 1 476  ? 127.080 170.468 138.026 1.00 28.12  ? 494  GLU A CA    1 
ATOM   3073  C  C     . GLU A 1 476  ? 125.700 169.989 138.456 1.00 28.12  ? 494  GLU A C     1 
ATOM   3074  O  O     . GLU A 1 476  ? 124.751 169.964 137.670 1.00 28.12  ? 494  GLU A O     1 
ATOM   3075  C  CB    . GLU A 1 476  ? 127.266 171.939 138.399 1.00 28.12  ? 494  GLU A CB    1 
ATOM   3076  C  CG    . GLU A 1 476  ? 128.582 172.526 137.924 1.00 28.12  ? 494  GLU A CG    1 
ATOM   3077  C  CD    . GLU A 1 476  ? 128.625 174.034 138.051 1.00 28.12  ? 494  GLU A CD    1 
ATOM   3078  O  OE1   . GLU A 1 476  ? 127.568 174.641 138.325 1.00 28.12  ? 494  GLU A OE1   1 
ATOM   3079  O  OE2   . GLU A 1 476  ? 129.716 174.612 137.875 1.00 28.12  ? 494  GLU A OE2   1 
ATOM   3080  N  N     . PHE A 1 477  ? 125.601 169.617 139.722 1.00 25.63  ? 495  PHE A N     1 
ATOM   3081  C  CA    . PHE A 1 477  ? 124.316 169.205 140.234 1.00 25.63  ? 495  PHE A CA    1 
ATOM   3082  C  C     . PHE A 1 477  ? 123.406 170.420 140.140 1.00 25.63  ? 495  PHE A C     1 
ATOM   3083  O  O     . PHE A 1 477  ? 123.885 171.544 139.985 1.00 25.63  ? 495  PHE A O     1 
ATOM   3084  C  CB    . PHE A 1 477  ? 124.440 168.658 141.654 1.00 25.63  ? 495  PHE A CB    1 
ATOM   3085  C  CG    . PHE A 1 477  ? 123.626 167.426 141.901 1.00 25.63  ? 495  PHE A CG    1 
ATOM   3086  C  CD1   . PHE A 1 477  ? 123.876 166.269 141.194 1.00 25.63  ? 495  PHE A CD1   1 
ATOM   3087  C  CD2   . PHE A 1 477  ? 122.621 167.422 142.846 1.00 25.63  ? 495  PHE A CD2   1 
ATOM   3088  C  CE1   . PHE A 1 477  ? 123.133 165.129 141.418 1.00 25.63  ? 495  PHE A CE1   1 
ATOM   3089  C  CE2   . PHE A 1 477  ? 121.873 166.287 143.078 1.00 25.63  ? 495  PHE A CE2   1 
ATOM   3090  C  CZ    . PHE A 1 477  ? 122.130 165.138 142.363 1.00 25.63  ? 495  PHE A CZ    1 
ATOM   3091  N  N     . LYS A 1 478  ? 122.104 170.217 140.241 1.00 33.20  ? 496  LYS A N     1 
ATOM   3092  C  CA    . LYS A 1 478  ? 121.143 171.298 140.048 1.00 33.20  ? 496  LYS A CA    1 
ATOM   3093  C  C     . LYS A 1 478  ? 120.297 171.538 141.293 1.00 33.20  ? 496  LYS A C     1 
ATOM   3094  O  O     . LYS A 1 478  ? 120.299 172.650 141.824 1.00 33.20  ? 496  LYS A O     1 
ATOM   3095  C  CB    . LYS A 1 478  ? 120.254 170.999 138.838 1.00 33.20  ? 496  LYS A CB    1 
ATOM   3096  C  CG    . LYS A 1 478  ? 120.945 171.179 137.499 1.00 33.20  ? 496  LYS A CG    1 
ATOM   3097  C  CD    . LYS A 1 478  ? 121.367 172.623 137.283 1.00 33.20  ? 496  LYS A CD    1 
ATOM   3098  C  CE    . LYS A 1 478  ? 122.092 172.792 135.957 1.00 33.20  ? 496  LYS A CE    1 
ATOM   3099  N  NZ    . LYS A 1 478  ? 121.258 172.344 134.806 1.00 33.20  ? 496  LYS A NZ    1 
ATOM   3100  N  N     . GLN A 1 479  ? 119.509 170.533 141.681 1.00 43.08  ? 497  GLN A N     1 
ATOM   3101  C  CA    . GLN A 1 479  ? 118.582 170.692 142.805 1.00 43.08  ? 497  GLN A CA    1 
ATOM   3102  C  C     . GLN A 1 479  ? 117.584 171.772 142.430 1.00 43.08  ? 497  GLN A C     1 
ATOM   3103  O  O     . GLN A 1 479  ? 117.091 171.776 141.305 1.00 43.08  ? 497  GLN A O     1 
ATOM   3104  C  CB    . GLN A 1 479  ? 119.324 171.027 144.095 1.00 43.08  ? 497  GLN A CB    1 
ATOM   3105  C  CG    . GLN A 1 479  ? 118.826 170.281 145.323 1.00 43.08  ? 497  GLN A CG    1 
ATOM   3106  C  CD    . GLN A 1 479  ? 119.118 168.793 145.275 1.00 43.08  ? 497  GLN A CD    1 
ATOM   3107  O  OE1   . GLN A 1 479  ? 119.444 168.242 144.226 1.00 43.08  ? 497  GLN A OE1   1 
ATOM   3108  N  NE2   . GLN A 1 479  ? 118.995 168.133 146.418 1.00 43.08  ? 497  GLN A NE2   1 
ATOM   3109  N  N     . LYS A 1 480  ? 117.261 172.677 143.349 1.00 50.68  ? 498  LYS A N     1 
ATOM   3110  C  CA    . LYS A 1 480  ? 116.391 173.803 143.011 1.00 50.68  ? 498  LYS A CA    1 
ATOM   3111  C  C     . LYS A 1 480  ? 116.876 175.083 143.679 1.00 50.68  ? 498  LYS A C     1 
ATOM   3112  O  O     . LYS A 1 480  ? 116.076 175.881 144.164 1.00 50.68  ? 498  LYS A O     1 
ATOM   3113  C  CB    . LYS A 1 480  ? 114.942 173.521 143.415 1.00 50.68  ? 498  LYS A CB    1 
ATOM   3114  C  CG    . LYS A 1 480  ? 114.221 172.544 142.504 1.00 50.68  ? 498  LYS A CG    1 
ATOM   3115  C  CD    . LYS A 1 480  ? 112.850 172.189 143.049 1.00 50.68  ? 498  LYS A CD    1 
ATOM   3116  C  CE    . LYS A 1 480  ? 112.162 171.154 142.174 1.00 50.68  ? 498  LYS A CE    1 
ATOM   3117  N  NZ    . LYS A 1 480  ? 110.847 170.734 142.731 1.00 50.68  ? 498  LYS A NZ    1 
ATOM   3118  N  N     . LEU A 1 512  ? 136.472 155.124 179.317 1.00 72.08  ? 530  LEU A N     1 
ATOM   3119  C  CA    . LEU A 1 512  ? 136.586 153.903 178.527 1.00 72.08  ? 530  LEU A CA    1 
ATOM   3120  C  C     . LEU A 1 512  ? 135.874 152.741 179.211 1.00 72.08  ? 530  LEU A C     1 
ATOM   3121  O  O     . LEU A 1 512  ? 136.211 152.370 180.335 1.00 72.08  ? 530  LEU A O     1 
ATOM   3122  C  CB    . LEU A 1 512  ? 138.057 153.554 178.290 1.00 72.08  ? 530  LEU A CB    1 
ATOM   3123  C  CG    . LEU A 1 512  ? 138.893 154.615 177.572 1.00 72.08  ? 530  LEU A CG    1 
ATOM   3124  C  CD1   . LEU A 1 512  ? 140.322 154.134 177.383 1.00 72.08  ? 530  LEU A CD1   1 
ATOM   3125  C  CD2   . LEU A 1 512  ? 138.266 154.980 176.237 1.00 72.08  ? 530  LEU A CD2   1 
ATOM   3126  N  N     . GLY A 1 513  ? 134.887 152.171 178.525 1.00 55.34  ? 531  GLY A N     1 
ATOM   3127  C  CA    . GLY A 1 513  ? 134.130 151.064 179.056 1.00 55.34  ? 531  GLY A CA    1 
ATOM   3128  C  C     . GLY A 1 513  ? 132.878 150.788 178.250 1.00 55.34  ? 531  GLY A C     1 
ATOM   3129  O  O     . GLY A 1 513  ? 132.624 151.417 177.219 1.00 55.34  ? 531  GLY A O     1 
ATOM   3130  N  N     . PRO A 1 514  ? 132.073 149.836 178.706 1.00 50.81  ? 532  PRO A N     1 
ATOM   3131  C  CA    . PRO A 1 514  ? 130.831 149.515 178.000 1.00 50.81  ? 532  PRO A CA    1 
ATOM   3132  C  C     . PRO A 1 514  ? 129.747 150.548 178.269 1.00 50.81  ? 532  PRO A C     1 
ATOM   3133  O  O     . PRO A 1 514  ? 129.835 151.368 179.184 1.00 50.81  ? 532  PRO A O     1 
ATOM   3134  C  CB    . PRO A 1 514  ? 130.444 148.151 178.578 1.00 50.81  ? 532  PRO A CB    1 
ATOM   3135  C  CG    . PRO A 1 514  ? 130.996 148.179 179.957 1.00 50.81  ? 532  PRO A CG    1 
ATOM   3136  C  CD    . PRO A 1 514  ? 132.278 148.973 179.882 1.00 50.81  ? 532  PRO A CD    1 
ATOM   3137  N  N     . CYS A 1 515  ? 128.709 150.490 177.442 1.00 57.79  ? 533  CYS A N     1 
ATOM   3138  C  CA    . CYS A 1 515  ? 127.539 151.342 177.581 1.00 57.79  ? 533  CYS A CA    1 
ATOM   3139  C  C     . CYS A 1 515  ? 126.338 150.502 177.990 1.00 57.79  ? 533  CYS A C     1 
ATOM   3140  O  O     . CYS A 1 515  ? 126.199 149.347 177.577 1.00 57.79  ? 533  CYS A O     1 
ATOM   3141  C  CB    . CYS A 1 515  ? 127.237 152.085 176.276 1.00 57.79  ? 533  CYS A CB    1 
ATOM   3142  S  SG    . CYS A 1 515  ? 128.547 153.201 175.734 1.00 57.79  ? 533  CYS A SG    1 
ATOM   3143  N  N     . SER A 1 516  ? 125.474 151.090 178.811 1.00 61.01  ? 534  SER A N     1 
ATOM   3144  C  CA    . SER A 1 516  ? 124.295 150.382 179.279 1.00 61.01  ? 534  SER A CA    1 
ATOM   3145  C  C     . SER A 1 516  ? 123.334 150.119 178.123 1.00 61.01  ? 534  SER A C     1 
ATOM   3146  O  O     . SER A 1 516  ? 123.420 150.729 177.054 1.00 61.01  ? 534  SER A O     1 
ATOM   3147  C  CB    . SER A 1 516  ? 123.591 151.176 180.379 1.00 61.01  ? 534  SER A CB    1 
ATOM   3148  O  OG    . SER A 1 516  ? 123.149 152.432 179.898 1.00 61.01  ? 534  SER A OG    1 
ATOM   3149  N  N     . GLU A 1 517  ? 122.411 149.181 178.350 1.00 65.66  ? 535  GLU A N     1 
ATOM   3150  C  CA    . GLU A 1 517  ? 121.451 148.822 177.312 1.00 65.66  ? 535  GLU A CA    1 
ATOM   3151  C  C     . GLU A 1 517  ? 120.568 150.008 176.943 1.00 65.66  ? 535  GLU A C     1 
ATOM   3152  O  O     . GLU A 1 517  ? 120.300 150.251 175.759 1.00 65.66  ? 535  GLU A O     1 
ATOM   3153  C  CB    . GLU A 1 517  ? 120.600 147.640 177.779 1.00 65.66  ? 535  GLU A CB    1 
ATOM   3154  C  CG    . GLU A 1 517  ? 119.855 146.919 176.665 1.00 65.66  ? 535  GLU A CG    1 
ATOM   3155  C  CD    . GLU A 1 517  ? 120.754 146.008 175.848 1.00 65.66  ? 535  GLU A CD    1 
ATOM   3156  O  OE1   . GLU A 1 517  ? 121.804 145.578 176.370 1.00 65.66  ? 535  GLU A OE1   1 
ATOM   3157  O  OE2   . GLU A 1 517  ? 120.409 145.723 174.683 1.00 65.66  ? 535  GLU A OE2   1 
ATOM   3158  N  N     . GLU A 1 518  ? 120.112 150.764 177.946 1.00 68.78  ? 536  GLU A N     1 
ATOM   3159  C  CA    . GLU A 1 518  ? 119.265 151.921 177.677 1.00 68.78  ? 536  GLU A CA    1 
ATOM   3160  C  C     . GLU A 1 518  ? 120.013 152.987 176.887 1.00 68.78  ? 536  GLU A C     1 
ATOM   3161  O  O     . GLU A 1 518  ? 119.460 153.577 175.953 1.00 68.78  ? 536  GLU A O     1 
ATOM   3162  C  CB    . GLU A 1 518  ? 118.734 152.499 178.989 1.00 68.78  ? 536  GLU A CB    1 
ATOM   3163  C  CG    . GLU A 1 518  ? 117.754 153.645 178.805 1.00 68.78  ? 536  GLU A CG    1 
ATOM   3164  C  CD    . GLU A 1 518  ? 116.481 153.216 178.102 1.00 68.78  ? 536  GLU A CD    1 
ATOM   3165  O  OE1   . GLU A 1 518  ? 116.067 152.050 178.277 1.00 68.78  ? 536  GLU A OE1   1 
ATOM   3166  O  OE2   . GLU A 1 518  ? 115.896 154.042 177.372 1.00 68.78  ? 536  GLU A OE2   1 
ATOM   3167  N  N     . GLU A 1 519  ? 121.271 153.253 177.249 1.00 67.12  ? 537  GLU A N     1 
ATOM   3168  C  CA    . GLU A 1 519  ? 122.054 154.250 176.524 1.00 67.12  ? 537  GLU A CA    1 
ATOM   3169  C  C     . GLU A 1 519  ? 122.309 153.816 175.086 1.00 67.12  ? 537  GLU A C     1 
ATOM   3170  O  O     . GLU A 1 519  ? 122.241 154.633 174.159 1.00 67.12  ? 537  GLU A O     1 
ATOM   3171  C  CB    . GLU A 1 519  ? 123.374 154.508 177.249 1.00 67.12  ? 537  GLU A CB    1 
ATOM   3172  C  CG    . GLU A 1 519  ? 124.296 155.481 176.536 1.00 67.12  ? 537  GLU A CG    1 
ATOM   3173  C  CD    . GLU A 1 519  ? 125.589 155.715 177.291 1.00 67.12  ? 537  GLU A CD    1 
ATOM   3174  O  OE1   . GLU A 1 519  ? 125.676 155.301 178.466 1.00 67.12  ? 537  GLU A OE1   1 
ATOM   3175  O  OE2   . GLU A 1 519  ? 126.520 156.310 176.709 1.00 67.12  ? 537  GLU A OE2   1 
ATOM   3176  N  N     . GLU A 1 520  ? 122.610 152.532 174.881 1.00 62.78  ? 538  GLU A N     1 
ATOM   3177  C  CA    . GLU A 1 520  ? 122.811 152.018 173.530 1.00 62.78  ? 538  GLU A CA    1 
ATOM   3178  C  C     . GLU A 1 520  ? 121.543 152.158 172.697 1.00 62.78  ? 538  GLU A C     1 
ATOM   3179  O  O     . GLU A 1 520  ? 121.592 152.597 171.539 1.00 62.78  ? 538  GLU A O     1 
ATOM   3180  C  CB    . GLU A 1 520  ? 123.258 150.558 173.603 1.00 62.78  ? 538  GLU A CB    1 
ATOM   3181  C  CG    . GLU A 1 520  ? 123.605 149.916 172.273 1.00 62.78  ? 538  GLU A CG    1 
ATOM   3182  C  CD    . GLU A 1 520  ? 124.073 148.481 172.438 1.00 62.78  ? 538  GLU A CD    1 
ATOM   3183  O  OE1   . GLU A 1 520  ? 124.052 147.977 173.580 1.00 62.78  ? 538  GLU A OE1   1 
ATOM   3184  O  OE2   . GLU A 1 520  ? 124.463 147.859 171.427 1.00 62.78  ? 538  GLU A OE2   1 
ATOM   3185  N  N     . PHE A 1 521  ? 120.394 151.803 173.279 1.00 64.49  ? 539  PHE A N     1 
ATOM   3186  C  CA    . PHE A 1 521  ? 119.122 151.944 172.577 1.00 64.49  ? 539  PHE A CA    1 
ATOM   3187  C  C     . PHE A 1 521  ? 118.833 153.403 172.248 1.00 64.49  ? 539  PHE A C     1 
ATOM   3188  O  O     . PHE A 1 521  ? 118.366 153.721 171.148 1.00 64.49  ? 539  PHE A O     1 
ATOM   3189  C  CB    . PHE A 1 521  ? 118.001 151.341 173.426 1.00 64.49  ? 539  PHE A CB    1 
ATOM   3190  C  CG    . PHE A 1 521  ? 116.645 151.394 172.782 1.00 64.49  ? 539  PHE A CG    1 
ATOM   3191  C  CD1   . PHE A 1 521  ? 116.298 150.494 171.788 1.00 64.49  ? 539  PHE A CD1   1 
ATOM   3192  C  CD2   . PHE A 1 521  ? 115.706 152.326 173.190 1.00 64.49  ? 539  PHE A CD2   1 
ATOM   3193  C  CE1   . PHE A 1 521  ? 115.047 150.534 171.202 1.00 64.49  ? 539  PHE A CE1   1 
ATOM   3194  C  CE2   . PHE A 1 521  ? 114.454 152.372 172.609 1.00 64.49  ? 539  PHE A CE2   1 
ATOM   3195  C  CZ    . PHE A 1 521  ? 114.124 151.474 171.614 1.00 64.49  ? 539  PHE A CZ    1 
ATOM   3196  N  N     . GLN A 1 522  ? 119.114 154.306 173.191 1.00 65.48  ? 540  GLN A N     1 
ATOM   3197  C  CA    . GLN A 1 522  ? 118.874 155.726 172.958 1.00 65.48  ? 540  GLN A CA    1 
ATOM   3198  C  C     . GLN A 1 522  ? 119.754 156.260 171.836 1.00 65.48  ? 540  GLN A C     1 
ATOM   3199  O  O     . GLN A 1 522  ? 119.285 157.020 170.982 1.00 65.48  ? 540  GLN A O     1 
ATOM   3200  C  CB    . GLN A 1 522  ? 119.111 156.513 174.247 1.00 65.48  ? 540  GLN A CB    1 
ATOM   3201  C  CG    . GLN A 1 522  ? 118.576 157.932 174.213 1.00 65.48  ? 540  GLN A CG    1 
ATOM   3202  C  CD    . GLN A 1 522  ? 117.060 157.984 174.240 1.00 65.48  ? 540  GLN A CD    1 
ATOM   3203  O  OE1   . GLN A 1 522  ? 116.401 157.018 174.626 1.00 65.48  ? 540  GLN A OE1   1 
ATOM   3204  N  NE2   . GLN A 1 522  ? 116.499 159.115 173.829 1.00 65.48  ? 540  GLN A NE2   1 
ATOM   3205  N  N     . GLN A 1 523  ? 121.034 155.877 171.820 1.00 62.43  ? 541  GLN A N     1 
ATOM   3206  C  CA    . GLN A 1 523  ? 121.923 156.331 170.754 1.00 62.43  ? 541  GLN A CA    1 
ATOM   3207  C  C     . GLN A 1 523  ? 121.485 155.787 169.400 1.00 62.43  ? 541  GLN A C     1 
ATOM   3208  O  O     . GLN A 1 523  ? 121.512 156.509 168.394 1.00 62.43  ? 541  GLN A O     1 
ATOM   3209  C  CB    . GLN A 1 523  ? 123.363 155.922 171.054 1.00 62.43  ? 541  GLN A CB    1 
ATOM   3210  C  CG    . GLN A 1 523  ? 123.957 156.599 172.274 1.00 62.43  ? 541  GLN A CG    1 
ATOM   3211  C  CD    . GLN A 1 523  ? 125.379 156.158 172.549 1.00 62.43  ? 541  GLN A CD    1 
ATOM   3212  O  OE1   . GLN A 1 523  ? 125.957 155.377 171.792 1.00 62.43  ? 541  GLN A OE1   1 
ATOM   3213  N  NE2   . GLN A 1 523  ? 125.953 156.658 173.637 1.00 62.43  ? 541  GLN A NE2   1 
ATOM   3214  N  N     . ASP A 1 524  ? 121.075 154.517 169.354 1.00 59.24  ? 542  ASP A N     1 
ATOM   3215  C  CA    . ASP A 1 524  ? 120.592 153.942 168.101 1.00 59.24  ? 542  ASP A CA    1 
ATOM   3216  C  C     . ASP A 1 524  ? 119.358 154.681 167.597 1.00 59.24  ? 542  ASP A C     1 
ATOM   3217  O  O     . ASP A 1 524  ? 119.261 155.024 166.410 1.00 59.24  ? 542  ASP A O     1 
ATOM   3218  C  CB    . ASP A 1 524  ? 120.291 152.456 168.292 1.00 59.24  ? 542  ASP A CB    1 
ATOM   3219  C  CG    . ASP A 1 524  ? 119.535 151.860 167.123 1.00 59.24  ? 542  ASP A CG    1 
ATOM   3220  O  OD1   . ASP A 1 524  ? 120.132 151.716 166.036 1.00 59.24  ? 542  ASP A OD1   1 
ATOM   3221  O  OD2   . ASP A 1 524  ? 118.341 151.534 167.292 1.00 59.24  ? 542  ASP A OD2   1 
ATOM   3222  N  N     . VAL A 1 525  ? 118.403 154.941 168.495 1.00 55.54  ? 543  VAL A N     1 
ATOM   3223  C  CA    . VAL A 1 525  ? 117.182 155.640 168.106 1.00 55.54  ? 543  VAL A CA    1 
ATOM   3224  C  C     . VAL A 1 525  ? 117.502 157.050 167.632 1.00 55.54  ? 543  VAL A C     1 
ATOM   3225  O  O     . VAL A 1 525  ? 116.940 157.528 166.640 1.00 55.54  ? 543  VAL A O     1 
ATOM   3226  C  CB    . VAL A 1 525  ? 116.175 155.644 169.272 1.00 55.54  ? 543  VAL A CB    1 
ATOM   3227  C  CG1   . VAL A 1 525  ? 115.036 156.609 168.992 1.00 55.54  ? 543  VAL A CG1   1 
ATOM   3228  C  CG2   . VAL A 1 525  ? 115.635 154.243 169.504 1.00 55.54  ? 543  VAL A CG2   1 
ATOM   3229  N  N     . MET A 1 526  ? 118.408 157.738 168.329 1.00 53.45  ? 544  MET A N     1 
ATOM   3230  C  CA    . MET A 1 526  ? 118.772 159.096 167.939 1.00 53.45  ? 544  MET A CA    1 
ATOM   3231  C  C     . MET A 1 526  ? 119.422 159.123 166.560 1.00 53.45  ? 544  MET A C     1 
ATOM   3232  O  O     . MET A 1 526  ? 119.106 159.987 165.732 1.00 53.45  ? 544  MET A O     1 
ATOM   3233  C  CB    . MET A 1 526  ? 119.700 159.700 168.991 1.00 53.45  ? 544  MET A CB    1 
ATOM   3234  C  CG    . MET A 1 526  ? 120.003 161.172 168.798 1.00 53.45  ? 544  MET A CG    1 
ATOM   3235  S  SD    . MET A 1 526  ? 121.068 161.814 170.104 1.00 53.45  ? 544  MET A SD    1 
ATOM   3236  C  CE    . MET A 1 526  ? 121.218 163.528 169.609 1.00 53.45  ? 544  MET A CE    1 
ATOM   3237  N  N     . ALA A 1 527  ? 120.327 158.177 166.290 1.00 47.65  ? 545  ALA A N     1 
ATOM   3238  C  CA    . ALA A 1 527  ? 120.967 158.128 164.979 1.00 47.65  ? 545  ALA A CA    1 
ATOM   3239  C  C     . ALA A 1 527  ? 119.957 157.837 163.876 1.00 47.65  ? 545  ALA A C     1 
ATOM   3240  O  O     . ALA A 1 527  ? 119.974 158.483 162.819 1.00 47.65  ? 545  ALA A O     1 
ATOM   3241  C  CB    . ALA A 1 527  ? 122.081 157.083 164.976 1.00 47.65  ? 545  ALA A CB    1 
ATOM   3242  N  N     . ARG A 1 528  ? 119.063 156.870 164.105 1.00 48.34  ? 546  ARG A N     1 
ATOM   3243  C  CA    . ARG A 1 528  ? 118.059 156.554 163.093 1.00 48.34  ? 546  ARG A CA    1 
ATOM   3244  C  C     . ARG A 1 528  ? 117.125 157.735 162.857 1.00 48.34  ? 546  ARG A C     1 
ATOM   3245  O  O     . ARG A 1 528  ? 116.737 158.012 161.716 1.00 48.34  ? 546  ARG A O     1 
ATOM   3246  C  CB    . ARG A 1 528  ? 117.268 155.312 163.501 1.00 48.34  ? 546  ARG A CB    1 
ATOM   3247  C  CG    . ARG A 1 528  ? 116.199 154.911 162.495 1.00 48.34  ? 546  ARG A CG    1 
ATOM   3248  C  CD    . ARG A 1 528  ? 115.515 153.606 162.872 1.00 48.34  ? 546  ARG A CD    1 
ATOM   3249  N  NE    . ARG A 1 528  ? 116.408 152.460 162.756 1.00 48.34  ? 546  ARG A NE    1 
ATOM   3250  C  CZ    . ARG A 1 528  ? 117.048 151.902 163.775 1.00 48.34  ? 546  ARG A CZ    1 
ATOM   3251  N  NH1   . ARG A 1 528  ? 116.910 152.356 165.010 1.00 48.34  ? 546  ARG A NH1   1 
ATOM   3252  N  NH2   . ARG A 1 528  ? 117.844 150.861 163.550 1.00 48.34  ? 546  ARG A NH2   1 
ATOM   3253  N  N     . ALA A 1 529  ? 116.753 158.444 163.925 1.00 46.24  ? 547  ALA A N     1 
ATOM   3254  C  CA    . ALA A 1 529  ? 115.892 159.611 163.778 1.00 46.24  ? 547  ALA A CA    1 
ATOM   3255  C  C     . ALA A 1 529  ? 116.582 160.712 162.987 1.00 46.24  ? 547  ALA A C     1 
ATOM   3256  O  O     . ALA A 1 529  ? 115.955 161.368 162.149 1.00 46.24  ? 547  ALA A O     1 
ATOM   3257  C  CB    . ALA A 1 529  ? 115.464 160.125 165.152 1.00 46.24  ? 547  ALA A CB    1 
ATOM   3258  N  N     . CYS A 1 530  ? 117.873 160.936 163.243 1.00 44.63  ? 548  CYS A N     1 
ATOM   3259  C  CA    . CYS A 1 530  ? 118.601 161.943 162.477 1.00 44.63  ? 548  CYS A CA    1 
ATOM   3260  C  C     . CYS A 1 530  ? 118.677 161.560 161.003 1.00 44.63  ? 548  CYS A C     1 
ATOM   3261  O  O     . CYS A 1 530  ? 118.511 162.413 160.120 1.00 44.63  ? 548  CYS A O     1 
ATOM   3262  C  CB    . CYS A 1 530  ? 119.999 162.136 163.058 1.00 44.63  ? 548  CYS A CB    1 
ATOM   3263  S  SG    . CYS A 1 530  ? 120.835 163.628 162.486 1.00 44.63  ? 548  CYS A SG    1 
ATOM   3264  N  N     . LEU A 1 531  ? 118.910 160.276 160.718 1.00 45.77  ? 549  LEU A N     1 
ATOM   3265  C  CA    . LEU A 1 531  ? 118.933 159.826 159.329 1.00 45.77  ? 549  LEU A CA    1 
ATOM   3266  C  C     . LEU A 1 531  ? 117.580 160.033 158.656 1.00 45.77  ? 549  LEU A C     1 
ATOM   3267  O  O     . LEU A 1 531  ? 117.511 160.501 157.513 1.00 45.77  ? 549  LEU A O     1 
ATOM   3268  C  CB    . LEU A 1 531  ? 119.342 158.355 159.255 1.00 45.77  ? 549  LEU A CB    1 
ATOM   3269  C  CG    . LEU A 1 531  ? 119.287 157.720 157.864 1.00 45.77  ? 549  LEU A CG    1 
ATOM   3270  C  CD1   . LEU A 1 531  ? 120.326 158.343 156.947 1.00 45.77  ? 549  LEU A CD1   1 
ATOM   3271  C  CD2   . LEU A 1 531  ? 119.467 156.212 157.945 1.00 45.77  ? 549  LEU A CD2   1 
ATOM   3272  N  N     . GLN A 1 532  ? 116.493 159.689 159.349 1.00 44.78  ? 550  GLN A N     1 
ATOM   3273  C  CA    . GLN A 1 532  ? 115.164 159.858 158.768 1.00 44.78  ? 550  GLN A CA    1 
ATOM   3274  C  C     . GLN A 1 532  ? 114.838 161.329 158.550 1.00 44.78  ? 550  GLN A C     1 
ATOM   3275  O  O     . GLN A 1 532  ? 114.186 161.688 157.563 1.00 44.78  ? 550  GLN A O     1 
ATOM   3276  C  CB    . GLN A 1 532  ? 114.111 159.199 159.657 1.00 44.78  ? 550  GLN A CB    1 
ATOM   3277  C  CG    . GLN A 1 532  ? 114.076 157.687 159.543 1.00 44.78  ? 550  GLN A CG    1 
ATOM   3278  C  CD    . GLN A 1 532  ? 113.648 157.219 158.167 1.00 44.78  ? 550  GLN A CD    1 
ATOM   3279  O  OE1   . GLN A 1 532  ? 112.967 157.939 157.435 1.00 44.78  ? 550  GLN A OE1   1 
ATOM   3280  N  NE2   . GLN A 1 532  ? 114.049 156.006 157.805 1.00 44.78  ? 550  GLN A NE2   1 
ATOM   3281  N  N     . LYS A 1 533  ? 115.270 162.193 159.469 1.00 46.79  ? 551  LYS A N     1 
ATOM   3282  C  CA    . LYS A 1 533  ? 115.089 163.627 159.276 1.00 46.79  ? 551  LYS A CA    1 
ATOM   3283  C  C     . LYS A 1 533  ? 115.851 164.111 158.050 1.00 46.79  ? 551  LYS A C     1 
ATOM   3284  O  O     . LYS A 1 533  ? 115.351 164.948 157.289 1.00 46.79  ? 551  LYS A O     1 
ATOM   3285  C  CB    . LYS A 1 533  ? 115.536 164.382 160.530 1.00 46.79  ? 551  LYS A CB    1 
ATOM   3286  C  CG    . LYS A 1 533  ? 115.543 165.896 160.395 1.00 46.79  ? 551  LYS A CG    1 
ATOM   3287  C  CD    . LYS A 1 533  ? 116.957 166.426 160.209 1.00 46.79  ? 551  LYS A CD    1 
ATOM   3288  C  CE    . LYS A 1 533  ? 116.965 167.935 160.038 1.00 46.79  ? 551  LYS A CE    1 
ATOM   3289  N  NZ    . LYS A 1 533  ? 118.345 168.464 159.858 1.00 46.79  ? 551  LYS A NZ    1 
ATOM   3290  N  N     . LEU A 1 534  ? 117.064 163.595 157.841 1.00 41.88  ? 552  LEU A N     1 
ATOM   3291  C  CA    . LEU A 1 534  ? 117.827 163.988 156.661 1.00 41.88  ? 552  LEU A CA    1 
ATOM   3292  C  C     . LEU A 1 534  ? 117.207 163.455 155.375 1.00 41.88  ? 552  LEU A C     1 
ATOM   3293  O  O     . LEU A 1 534  ? 117.322 164.098 154.325 1.00 41.88  ? 552  LEU A O     1 
ATOM   3294  C  CB    . LEU A 1 534  ? 119.275 163.520 156.784 1.00 41.88  ? 552  LEU A CB    1 
ATOM   3295  C  CG    . LEU A 1 534  ? 120.215 164.596 157.321 1.00 41.88  ? 552  LEU A CG    1 
ATOM   3296  C  CD1   . LEU A 1 534  ? 121.667 164.178 157.175 1.00 41.88  ? 552  LEU A CD1   1 
ATOM   3297  C  CD2   . LEU A 1 534  ? 119.952 165.901 156.598 1.00 41.88  ? 552  LEU A CD2   1 
ATOM   3298  N  N     . LYS A 1 535  ? 116.549 162.297 155.430 1.00 46.16  ? 553  LYS A N     1 
ATOM   3299  C  CA    . LYS A 1 535  ? 115.928 161.708 154.248 1.00 46.16  ? 553  LYS A CA    1 
ATOM   3300  C  C     . LYS A 1 535  ? 114.591 162.344 153.892 1.00 46.16  ? 553  LYS A C     1 
ATOM   3301  O  O     . LYS A 1 535  ? 113.856 161.785 153.069 1.00 46.16  ? 553  LYS A O     1 
ATOM   3302  C  CB    . LYS A 1 535  ? 115.741 160.202 154.438 1.00 46.16  ? 553  LYS A CB    1 
ATOM   3303  C  CG    . LYS A 1 535  ? 117.024 159.406 154.384 1.00 46.16  ? 553  LYS A CG    1 
ATOM   3304  C  CD    . LYS A 1 535  ? 116.747 157.955 154.034 1.00 46.16  ? 553  LYS A CD    1 
ATOM   3305  C  CE    . LYS A 1 535  ? 115.793 157.323 155.030 1.00 46.16  ? 553  LYS A CE    1 
ATOM   3306  N  NZ    . LYS A 1 535  ? 115.478 155.913 154.672 1.00 46.16  ? 553  LYS A NZ    1 
ATOM   3307  N  N     . GLY A 1 536  ? 114.254 163.484 154.484 1.00 55.23  ? 554  GLY A N     1 
ATOM   3308  C  CA    . GLY A 1 536  ? 113.011 164.153 154.162 1.00 55.23  ? 554  GLY A CA    1 
ATOM   3309  C  C     . GLY A 1 536  ? 113.229 165.457 153.426 1.00 55.23  ? 554  GLY A C     1 
ATOM   3310  O  O     . GLY A 1 536  ? 112.279 166.203 153.172 1.00 55.23  ? 554  GLY A O     1 
ATOM   3311  N  N     . THR A 1 537  ? 114.472 165.733 153.044 1.00 55.07  ? 555  THR A N     1 
ATOM   3312  C  CA    . THR A 1 537  ? 114.785 166.997 152.382 1.00 55.07  ? 555  THR A CA    1 
ATOM   3313  C  C     . THR A 1 537  ? 114.704 166.899 150.858 1.00 55.07  ? 555  THR A C     1 
ATOM   3314  O  O     . THR A 1 537  ? 115.241 167.744 150.147 1.00 55.07  ? 555  THR A O     1 
ATOM   3315  C  CB    . THR A 1 537  ? 116.183 167.497 152.790 1.00 55.07  ? 555  THR A CB    1 
ATOM   3316  O  OG1   . THR A 1 537  ? 116.430 167.166 154.162 1.00 55.07  ? 555  THR A OG1   1 
ATOM   3317  C  CG2   . THR A 1 537  ? 116.291 169.004 152.609 1.00 55.07  ? 555  THR A CG2   1 
ATOM   3318  N  N     . THR A 1 538  ? 114.029 165.877 150.352 1.00 55.62  ? 556  THR A N     1 
ATOM   3319  C  CA    . THR A 1 538  ? 113.883 165.711 148.911 1.00 55.62  ? 556  THR A CA    1 
ATOM   3320  C  C     . THR A 1 538  ? 113.072 166.826 148.268 1.00 55.62  ? 556  THR A C     1 
ATOM   3321  O  O     . THR A 1 538  ? 112.872 166.801 147.050 1.00 55.62  ? 556  THR A O     1 
ATOM   3322  C  CB    . THR A 1 538  ? 113.230 164.363 148.594 1.00 55.62  ? 556  THR A CB    1 
ATOM   3323  O  OG1   . THR A 1 538  ? 111.881 164.359 149.077 1.00 55.62  ? 556  THR A OG1   1 
ATOM   3324  C  CG2   . THR A 1 538  ? 113.996 163.231 149.253 1.00 55.62  ? 556  THR A CG2   1 
ATOM   3325  N  N     . GLU A 1 539  ? 112.591 167.792 149.053 1.00 58.78  ? 557  GLU A N     1 
ATOM   3326  C  CA    . GLU A 1 539  ? 111.775 168.871 148.513 1.00 58.78  ? 557  GLU A CA    1 
ATOM   3327  C  C     . GLU A 1 539  ? 112.563 169.800 147.600 1.00 58.78  ? 557  GLU A C     1 
ATOM   3328  O  O     . GLU A 1 539  ? 111.957 170.596 146.876 1.00 58.78  ? 557  GLU A O     1 
ATOM   3329  C  CB    . GLU A 1 539  ? 111.155 169.674 149.657 1.00 58.78  ? 557  GLU A CB    1 
ATOM   3330  C  CG    . GLU A 1 539  ? 110.797 168.837 150.877 1.00 58.78  ? 557  GLU A CG    1 
ATOM   3331  C  CD    . GLU A 1 539  ? 109.813 167.727 150.563 1.00 58.78  ? 557  GLU A CD    1 
ATOM   3332  O  OE1   . GLU A 1 539  ? 108.925 167.936 149.709 1.00 58.78  ? 557  GLU A OE1   1 
ATOM   3333  O  OE2   . GLU A 1 539  ? 109.931 166.640 151.168 1.00 58.78  ? 557  GLU A OE2   1 
ATOM   3334  N  N     . LEU A 1 540  ? 113.893 169.726 147.622 1.00 50.28  ? 558  LEU A N     1 
ATOM   3335  C  CA    . LEU A 1 540  ? 114.719 170.641 146.848 1.00 50.28  ? 558  LEU A CA    1 
ATOM   3336  C  C     . LEU A 1 540  ? 115.301 170.013 145.588 1.00 50.28  ? 558  LEU A C     1 
ATOM   3337  O  O     . LEU A 1 540  ? 115.727 170.747 144.691 1.00 50.28  ? 558  LEU A O     1 
ATOM   3338  C  CB    . LEU A 1 540  ? 115.855 171.183 147.722 1.00 50.28  ? 558  LEU A CB    1 
ATOM   3339  C  CG    . LEU A 1 540  ? 116.543 172.464 147.248 1.00 50.28  ? 558  LEU A CG    1 
ATOM   3340  C  CD1   . LEU A 1 540  ? 115.528 173.584 147.099 1.00 50.28  ? 558  LEU A CD1   1 
ATOM   3341  C  CD2   . LEU A 1 540  ? 117.655 172.866 148.203 1.00 50.28  ? 558  LEU A CD2   1 
ATOM   3342  N  N     . LEU A 1 541  ? 115.333 168.686 145.492 1.00 49.33  ? 559  LEU A N     1 
ATOM   3343  C  CA    . LEU A 1 541  ? 115.907 168.050 144.317 1.00 49.33  ? 559  LEU A CA    1 
ATOM   3344  C  C     . LEU A 1 541  ? 115.002 168.270 143.103 1.00 49.33  ? 559  LEU A C     1 
ATOM   3345  O  O     . LEU A 1 541  ? 113.784 168.407 143.246 1.00 49.33  ? 559  LEU A O     1 
ATOM   3346  C  CB    . LEU A 1 541  ? 116.130 166.556 144.566 1.00 49.33  ? 559  LEU A CB    1 
ATOM   3347  C  CG    . LEU A 1 541  ? 114.999 165.638 145.037 1.00 49.33  ? 559  LEU A CG    1 
ATOM   3348  C  CD1   . LEU A 1 541  ? 114.092 165.195 143.894 1.00 49.33  ? 559  LEU A CD1   1 
ATOM   3349  C  CD2   . LEU A 1 541  ? 115.582 164.430 145.752 1.00 49.33  ? 559  LEU A CD2   1 
ATOM   3350  N  N     . PRO A 1 542  ? 115.568 168.310 141.898 1.00 49.37  ? 560  PRO A N     1 
ATOM   3351  C  CA    . PRO A 1 542  ? 114.759 168.623 140.718 1.00 49.37  ? 560  PRO A CA    1 
ATOM   3352  C  C     . PRO A 1 542  ? 113.868 167.457 140.322 1.00 49.37  ? 560  PRO A C     1 
ATOM   3353  O  O     . PRO A 1 542  ? 114.059 166.314 140.742 1.00 49.37  ? 560  PRO A O     1 
ATOM   3354  C  CB    . PRO A 1 542  ? 115.807 168.914 139.641 1.00 49.37  ? 560  PRO A CB    1 
ATOM   3355  C  CG    . PRO A 1 542  ? 116.955 168.056 140.024 1.00 49.37  ? 560  PRO A CG    1 
ATOM   3356  C  CD    . PRO A 1 542  ? 116.958 167.982 141.532 1.00 49.37  ? 560  PRO A CD    1 
ATOM   3357  N  N     . LYS A 1 543  ? 112.866 167.773 139.499 1.00 64.98  ? 561  LYS A N     1 
ATOM   3358  C  CA    . LYS A 1 543  ? 111.910 166.759 139.066 1.00 64.98  ? 561  LYS A CA    1 
ATOM   3359  C  C     . LYS A 1 543  ? 112.579 165.708 138.189 1.00 64.98  ? 561  LYS A C     1 
ATOM   3360  O  O     . LYS A 1 543  ? 112.376 164.503 138.379 1.00 64.98  ? 561  LYS A O     1 
ATOM   3361  C  CB    . LYS A 1 543  ? 110.747 167.422 138.329 1.00 64.98  ? 561  LYS A CB    1 
ATOM   3362  C  CG    . LYS A 1 543  ? 109.965 168.412 139.177 1.00 64.98  ? 561  LYS A CG    1 
ATOM   3363  C  CD    . LYS A 1 543  ? 108.910 169.135 138.359 1.00 64.98  ? 561  LYS A CD    1 
ATOM   3364  C  CE    . LYS A 1 543  ? 108.004 168.153 137.637 1.00 64.98  ? 561  LYS A CE    1 
ATOM   3365  N  NZ    . LYS A 1 543  ? 107.340 167.217 138.585 1.00 64.98  ? 561  LYS A NZ    1 
ATOM   3366  N  N     . ARG A 1 544  ? 113.383 166.146 137.220 1.00 67.39  ? 562  ARG A N     1 
ATOM   3367  C  CA    . ARG A 1 544  ? 114.111 165.226 136.360 1.00 67.39  ? 562  ARG A CA    1 
ATOM   3368  C  C     . ARG A 1 544  ? 115.533 165.086 136.877 1.00 67.39  ? 562  ARG A C     1 
ATOM   3369  O  O     . ARG A 1 544  ? 116.304 166.056 136.807 1.00 67.39  ? 562  ARG A O     1 
ATOM   3370  C  CB    . ARG A 1 544  ? 114.118 165.720 134.915 1.00 67.39  ? 562  ARG A CB    1 
ATOM   3371  C  CG    . ARG A 1 544  ? 112.769 165.666 134.223 1.00 67.39  ? 562  ARG A CG    1 
ATOM   3372  C  CD    . ARG A 1 544  ? 112.886 166.112 132.774 1.00 67.39  ? 562  ARG A CD    1 
ATOM   3373  N  NE    . ARG A 1 544  ? 113.416 167.466 132.664 1.00 67.39  ? 562  ARG A NE    1 
ATOM   3374  C  CZ    . ARG A 1 544  ? 112.670 168.561 132.631 1.00 67.39  ? 562  ARG A CZ    1 
ATOM   3375  N  NH1   . ARG A 1 544  ? 111.350 168.499 132.690 1.00 67.39  ? 562  ARG A NH1   1 
ATOM   3376  N  NH2   . ARG A 1 544  ? 113.263 169.748 132.538 1.00 67.39  ? 562  ARG A NH2   1 
ATOM   3377  N  N     . PRO A 1 545  ? 115.926 163.929 137.405 1.00 44.45  ? 563  PRO A N     1 
ATOM   3378  C  CA    . PRO A 1 545  ? 117.299 163.772 137.898 1.00 44.45  ? 563  PRO A CA    1 
ATOM   3379  C  C     . PRO A 1 545  ? 118.306 163.925 136.769 1.00 44.45  ? 563  PRO A C     1 
ATOM   3380  O  O     . PRO A 1 545  ? 118.063 163.503 135.636 1.00 44.45  ? 563  PRO A O     1 
ATOM   3381  C  CB    . PRO A 1 545  ? 117.311 162.352 138.477 1.00 44.45  ? 563  PRO A CB    1 
ATOM   3382  C  CG    . PRO A 1 545  ? 115.871 162.008 138.699 1.00 44.45  ? 563  PRO A CG    1 
ATOM   3383  C  CD    . PRO A 1 545  ? 115.122 162.714 137.616 1.00 44.45  ? 563  PRO A CD    1 
ATOM   3384  N  N     . GLN A 1 546  ? 119.444 164.536 137.086 1.00 26.90  ? 564  GLN A N     1 
ATOM   3385  C  CA    . GLN A 1 546  ? 120.524 164.609 136.119 1.00 26.90  ? 564  GLN A CA    1 
ATOM   3386  C  C     . GLN A 1 546  ? 121.081 163.217 135.855 1.00 26.90  ? 564  GLN A C     1 
ATOM   3387  O  O     . GLN A 1 546  ? 120.798 162.255 136.573 1.00 26.90  ? 564  GLN A O     1 
ATOM   3388  C  CB    . GLN A 1 546  ? 121.633 165.530 136.614 1.00 26.90  ? 564  GLN A CB    1 
ATOM   3389  C  CG    . GLN A 1 546  ? 121.359 166.992 136.374 1.00 26.90  ? 564  GLN A CG    1 
ATOM   3390  C  CD    . GLN A 1 546  ? 122.555 167.855 136.689 1.00 26.90  ? 564  GLN A CD    1 
ATOM   3391  O  OE1   . GLN A 1 546  ? 123.320 167.561 137.604 1.00 26.90  ? 564  GLN A OE1   1 
ATOM   3392  N  NE2   . GLN A 1 546  ? 122.733 168.921 135.922 1.00 26.90  ? 564  GLN A NE2   1 
ATOM   3393  N  N     . HIS A 1 547  ? 121.887 163.113 134.807 1.00 23.31  ? 565  HIS A N     1 
ATOM   3394  C  CA    . HIS A 1 547  ? 122.473 161.842 134.403 1.00 23.31  ? 565  HIS A CA    1 
ATOM   3395  C  C     . HIS A 1 547  ? 123.987 161.959 134.498 1.00 23.31  ? 565  HIS A C     1 
ATOM   3396  O  O     . HIS A 1 547  ? 124.635 162.479 133.587 1.00 23.31  ? 565  HIS A O     1 
ATOM   3397  C  CB    . HIS A 1 547  ? 122.036 161.458 132.995 1.00 23.31  ? 565  HIS A CB    1 
ATOM   3398  C  CG    . HIS A 1 547  ? 122.549 160.126 132.554 1.00 23.31  ? 565  HIS A CG    1 
ATOM   3399  N  ND1   . HIS A 1 547  ? 123.388 159.972 131.472 1.00 23.31  ? 565  HIS A ND1   1 
ATOM   3400  C  CD2   . HIS A 1 547  ? 122.356 158.886 133.062 1.00 23.31  ? 565  HIS A CD2   1 
ATOM   3401  C  CE1   . HIS A 1 547  ? 123.681 158.693 131.326 1.00 23.31  ? 565  HIS A CE1   1 
ATOM   3402  N  NE2   . HIS A 1 547  ? 123.069 158.013 132.278 1.00 23.31  ? 565  HIS A NE2   1 
ATOM   3403  N  N     . LEU A 1 548  ? 124.539 161.464 135.602 1.00 20.66  ? 566  LEU A N     1 
ATOM   3404  C  CA    . LEU A 1 548  ? 125.978 161.401 135.825 1.00 20.66  ? 566  LEU A CA    1 
ATOM   3405  C  C     . LEU A 1 548  ? 126.685 162.718 135.490 1.00 20.66  ? 566  LEU A C     1 
ATOM   3406  O  O     . LEU A 1 548  ? 127.554 162.757 134.616 1.00 20.66  ? 566  LEU A O     1 
ATOM   3407  C  CB    . LEU A 1 548  ? 126.589 160.253 135.033 1.00 20.66  ? 566  LEU A CB    1 
ATOM   3408  C  CG    . LEU A 1 548  ? 125.859 158.910 135.086 1.00 20.66  ? 566  LEU A CG    1 
ATOM   3409  C  CD1   . LEU A 1 548  ? 126.647 157.857 134.339 1.00 20.66  ? 566  LEU A CD1   1 
ATOM   3410  C  CD2   . LEU A 1 548  ? 125.602 158.474 136.516 1.00 20.66  ? 566  LEU A CD2   1 
ATOM   3411  N  N     . PRO A 1 549  ? 126.330 163.814 136.164 1.00 21.47  ? 567  PRO A N     1 
ATOM   3412  C  CA    . PRO A 1 549  ? 127.003 165.087 135.876 1.00 21.47  ? 567  PRO A CA    1 
ATOM   3413  C  C     . PRO A 1 549  ? 128.477 165.080 136.229 1.00 21.47  ? 567  PRO A C     1 
ATOM   3414  O  O     . PRO A 1 549  ? 129.223 165.916 135.708 1.00 21.47  ? 567  PRO A O     1 
ATOM   3415  C  CB    . PRO A 1 549  ? 126.227 166.090 136.733 1.00 21.47  ? 567  PRO A CB    1 
ATOM   3416  C  CG    . PRO A 1 549  ? 125.744 165.281 137.875 1.00 21.47  ? 567  PRO A CG    1 
ATOM   3417  C  CD    . PRO A 1 549  ? 125.415 163.929 137.310 1.00 21.47  ? 567  PRO A CD    1 
ATOM   3418  N  N     . GLY A 1 550  ? 128.924 164.162 137.089 1.00 26.71  ? 568  GLY A N     1 
ATOM   3419  C  CA    . GLY A 1 550  ? 130.327 164.111 137.455 1.00 26.71  ? 568  GLY A CA    1 
ATOM   3420  C  C     . GLY A 1 550  ? 131.216 163.422 136.445 1.00 26.71  ? 568  GLY A C     1 
ATOM   3421  O  O     . GLY A 1 550  ? 132.435 163.605 136.486 1.00 26.71  ? 568  GLY A O     1 
ATOM   3422  N  N     . HIS A 1 551  ? 130.639 162.628 135.554 1.00 38.40  ? 569  HIS A N     1 
ATOM   3423  C  CA    . HIS A 1 551  ? 131.421 161.944 134.540 1.00 38.40  ? 569  HIS A CA    1 
ATOM   3424  C  C     . HIS A 1 551  ? 131.666 162.860 133.344 1.00 38.40  ? 569  HIS A C     1 
ATOM   3425  O  O     . HIS A 1 551  ? 130.899 163.794 133.103 1.00 38.40  ? 569  HIS A O     1 
ATOM   3426  C  CB    . HIS A 1 551  ? 130.708 160.676 134.088 1.00 38.40  ? 569  HIS A CB    1 
ATOM   3427  C  CG    . HIS A 1 551  ? 130.615 159.632 135.152 1.00 38.40  ? 569  HIS A CG    1 
ATOM   3428  N  ND1   . HIS A 1 551  ? 130.154 158.357 134.907 1.00 38.40  ? 569  HIS A ND1   1 
ATOM   3429  C  CD2   . HIS A 1 551  ? 130.924 159.672 136.469 1.00 38.40  ? 569  HIS A CD2   1 
ATOM   3430  C  CE1   . HIS A 1 551  ? 130.183 157.656 136.026 1.00 38.40  ? 569  HIS A CE1   1 
ATOM   3431  N  NE2   . HIS A 1 551  ? 130.647 158.431 136.989 1.00 38.40  ? 569  HIS A NE2   1 
ATOM   3432  N  N     . PRO A 1 552  ? 132.732 162.620 132.584 1.00 27.28  ? 570  PRO A N     1 
ATOM   3433  C  CA    . PRO A 1 552  ? 133.024 163.478 131.434 1.00 27.28  ? 570  PRO A CA    1 
ATOM   3434  C  C     . PRO A 1 552  ? 132.005 163.281 130.322 1.00 27.28  ? 570  PRO A C     1 
ATOM   3435  O  O     . PRO A 1 552  ? 131.203 162.346 130.322 1.00 27.28  ? 570  PRO A O     1 
ATOM   3436  C  CB    . PRO A 1 552  ? 134.425 163.039 131.003 1.00 27.28  ? 570  PRO A CB    1 
ATOM   3437  C  CG    . PRO A 1 552  ? 134.579 161.679 131.545 1.00 27.28  ? 570  PRO A CG    1 
ATOM   3438  C  CD    . PRO A 1 552  ? 133.813 161.653 132.827 1.00 27.28  ? 570  PRO A CD    1 
ATOM   3439  N  N     . GLY A 1 553  ? 132.045 164.208 129.362 1.00 30.64  ? 571  GLY A N     1 
ATOM   3440  C  CA    . GLY A 1 553  ? 130.988 164.278 128.366 1.00 30.64  ? 571  GLY A CA    1 
ATOM   3441  C  C     . GLY A 1 553  ? 130.870 163.020 127.528 1.00 30.64  ? 571  GLY A C     1 
ATOM   3442  O  O     . GLY A 1 553  ? 129.776 162.482 127.347 1.00 30.64  ? 571  GLY A O     1 
ATOM   3443  N  N     . TRP A 1 554  ? 131.997 162.529 127.008 1.00 38.40  ? 572  TRP A N     1 
ATOM   3444  C  CA    . TRP A 1 554  ? 131.954 161.347 126.156 1.00 38.40  ? 572  TRP A CA    1 
ATOM   3445  C  C     . TRP A 1 554  ? 131.547 160.098 126.919 1.00 38.40  ? 572  TRP A C     1 
ATOM   3446  O  O     . TRP A 1 554  ? 131.198 159.093 126.293 1.00 38.40  ? 572  TRP A O     1 
ATOM   3447  C  CB    . TRP A 1 554  ? 133.306 161.117 125.484 1.00 38.40  ? 572  TRP A CB    1 
ATOM   3448  C  CG    . TRP A 1 554  ? 134.416 160.828 126.429 1.00 38.40  ? 572  TRP A CG    1 
ATOM   3449  C  CD1   . TRP A 1 554  ? 135.296 161.723 126.943 1.00 38.40  ? 572  TRP A CD1   1 
ATOM   3450  C  CD2   . TRP A 1 554  ? 134.780 159.552 126.967 1.00 38.40  ? 572  TRP A CD2   1 
ATOM   3451  N  NE1   . TRP A 1 554  ? 136.182 161.091 127.774 1.00 38.40  ? 572  TRP A NE1   1 
ATOM   3452  C  CE2   . TRP A 1 554  ? 135.888 159.756 127.805 1.00 38.40  ? 572  TRP A CE2   1 
ATOM   3453  C  CE3   . TRP A 1 554  ? 134.274 158.259 126.823 1.00 38.40  ? 572  TRP A CE3   1 
ATOM   3454  C  CZ2   . TRP A 1 554  ? 136.499 158.720 128.496 1.00 38.40  ? 572  TRP A CZ2   1 
ATOM   3455  C  CZ3   . TRP A 1 554  ? 134.882 157.232 127.512 1.00 38.40  ? 572  TRP A CZ3   1 
ATOM   3456  C  CH2   . TRP A 1 554  ? 135.982 157.467 128.337 1.00 38.40  ? 572  TRP A CH2   1 
ATOM   3457  N  N     . TYR A 1 555  ? 131.587 160.136 128.251 1.00 38.40  ? 573  TYR A N     1 
ATOM   3458  C  CA    . TYR A 1 555  ? 131.201 158.973 129.040 1.00 38.40  ? 573  TYR A CA    1 
ATOM   3459  C  C     . TYR A 1 555  ? 129.692 158.897 129.204 1.00 38.40  ? 573  TYR A C     1 
ATOM   3460  O  O     . TYR A 1 555  ? 129.112 157.811 129.097 1.00 38.40  ? 573  TYR A O     1 
ATOM   3461  C  CB    . TYR A 1 555  ? 131.891 159.013 130.406 1.00 38.40  ? 573  TYR A CB    1 
ATOM   3462  C  CG    . TYR A 1 555  ? 131.900 157.700 131.172 1.00 38.40  ? 573  TYR A CG    1 
ATOM   3463  C  CD1   . TYR A 1 555  ? 130.730 157.005 131.429 1.00 38.40  ? 573  TYR A CD1   1 
ATOM   3464  C  CD2   . TYR A 1 555  ? 133.083 157.168 131.647 1.00 38.40  ? 573  TYR A CD2   1 
ATOM   3465  C  CE1   . TYR A 1 555  ? 130.741 155.825 132.121 1.00 38.40  ? 573  TYR A CE1   1 
ATOM   3466  C  CE2   . TYR A 1 555  ? 133.098 155.987 132.340 1.00 38.40  ? 573  TYR A CE2   1 
ATOM   3467  C  CZ    . TYR A 1 555  ? 131.929 155.322 132.575 1.00 38.40  ? 573  TYR A CZ    1 
ATOM   3468  O  OH    . TYR A 1 555  ? 131.946 154.144 133.273 1.00 38.40  ? 573  TYR A OH    1 
ATOM   3469  N  N     . ARG A 1 556  ? 129.042 160.034 129.462 1.00 29.80  ? 574  ARG A N     1 
ATOM   3470  C  CA    . ARG A 1 556  ? 127.609 160.018 129.729 1.00 29.80  ? 574  ARG A CA    1 
ATOM   3471  C  C     . ARG A 1 556  ? 126.829 159.405 128.574 1.00 29.80  ? 574  ARG A C     1 
ATOM   3472  O  O     . ARG A 1 556  ? 125.792 158.772 128.796 1.00 29.80  ? 574  ARG A O     1 
ATOM   3473  C  CB    . ARG A 1 556  ? 127.112 161.433 130.020 1.00 29.80  ? 574  ARG A CB    1 
ATOM   3474  C  CG    . ARG A 1 556  ? 127.648 162.019 131.309 1.00 29.80  ? 574  ARG A CG    1 
ATOM   3475  C  CD    . ARG A 1 556  ? 127.024 163.369 131.605 1.00 29.80  ? 574  ARG A CD    1 
ATOM   3476  N  NE    . ARG A 1 556  ? 127.482 164.404 130.690 1.00 29.80  ? 574  ARG A NE    1 
ATOM   3477  C  CZ    . ARG A 1 556  ? 128.502 165.216 130.929 1.00 29.80  ? 574  ARG A CZ    1 
ATOM   3478  N  NH1   . ARG A 1 556  ? 129.202 165.135 132.048 1.00 29.80  ? 574  ARG A NH1   1 
ATOM   3479  N  NH2   . ARG A 1 556  ? 128.827 166.134 130.024 1.00 29.80  ? 574  ARG A NH2   1 
ATOM   3480  N  N     . LYS A 1 557  ? 127.308 159.579 127.340 1.00 38.40  ? 575  LYS A N     1 
ATOM   3481  C  CA    . LYS A 1 557  ? 126.690 158.895 126.210 1.00 38.40  ? 575  LYS A CA    1 
ATOM   3482  C  C     . LYS A 1 557  ? 126.814 157.385 126.350 1.00 38.40  ? 575  LYS A C     1 
ATOM   3483  O  O     . LYS A 1 557  ? 125.853 156.648 126.106 1.00 38.40  ? 575  LYS A O     1 
ATOM   3484  C  CB    . LYS A 1 557  ? 127.330 159.356 124.905 1.00 38.40  ? 575  LYS A CB    1 
ATOM   3485  C  CG    . LYS A 1 557  ? 127.417 160.857 124.755 1.00 38.40  ? 575  LYS A CG    1 
ATOM   3486  C  CD    . LYS A 1 557  ? 128.170 161.223 123.493 1.00 38.40  ? 575  LYS A CD    1 
ATOM   3487  C  CE    . LYS A 1 557  ? 128.368 162.722 123.389 1.00 38.40  ? 575  LYS A CE    1 
ATOM   3488  N  NZ    . LYS A 1 557  ? 129.199 163.084 122.211 1.00 38.40  ? 575  LYS A NZ    1 
ATOM   3489  N  N     . LEU A 1 558  ? 127.996 156.906 126.742 1.00 25.28  ? 576  LEU A N     1 
ATOM   3490  C  CA    . LEU A 1 558  ? 128.217 155.469 126.851 1.00 25.28  ? 576  LEU A CA    1 
ATOM   3491  C  C     . LEU A 1 558  ? 127.366 154.866 127.958 1.00 25.28  ? 576  LEU A C     1 
ATOM   3492  O  O     . LEU A 1 558  ? 126.650 153.884 127.740 1.00 25.28  ? 576  LEU A O     1 
ATOM   3493  C  CB    . LEU A 1 558  ? 129.698 155.184 127.099 1.00 25.28  ? 576  LEU A CB    1 
ATOM   3494  C  CG    . LEU A 1 558  ? 130.676 155.893 126.163 1.00 25.28  ? 576  LEU A CG    1 
ATOM   3495  C  CD1   . LEU A 1 558  ? 132.097 155.462 126.447 1.00 25.28  ? 576  LEU A CD1   1 
ATOM   3496  C  CD2   . LEU A 1 558  ? 130.313 155.626 124.717 1.00 25.28  ? 576  LEU A CD2   1 
ATOM   3497  N  N     . CYS A 1 559  ? 127.421 155.446 129.146 1.00 23.71  ? 577  CYS A N     1 
ATOM   3498  C  CA    . CYS A 1 559  ? 126.706 154.879 130.278 1.00 23.71  ? 577  CYS A CA    1 
ATOM   3499  C  C     . CYS A 1 559  ? 125.207 155.083 130.100 1.00 23.71  ? 577  CYS A C     1 
ATOM   3500  O  O     . CYS A 1 559  ? 124.772 156.193 129.777 1.00 23.71  ? 577  CYS A O     1 
ATOM   3501  C  CB    . CYS A 1 559  ? 127.181 155.516 131.577 1.00 23.71  ? 577  CYS A CB    1 
ATOM   3502  S  SG    . CYS A 1 559  ? 126.776 154.560 133.048 1.00 23.71  ? 577  CYS A SG    1 
ATOM   3503  N  N     . PRO A 1 560  ? 124.390 154.051 130.301 1.00 23.86  ? 578  PRO A N     1 
ATOM   3504  C  CA    . PRO A 1 560  ? 122.947 154.185 130.073 1.00 23.86  ? 578  PRO A CA    1 
ATOM   3505  C  C     . PRO A 1 560  ? 122.310 155.173 131.038 1.00 23.86  ? 578  PRO A C     1 
ATOM   3506  O  O     . PRO A 1 560  ? 122.917 155.638 132.004 1.00 23.86  ? 578  PRO A O     1 
ATOM   3507  C  CB    . PRO A 1 560  ? 122.415 152.765 130.299 1.00 23.86  ? 578  PRO A CB    1 
ATOM   3508  C  CG    . PRO A 1 560  ? 123.608 151.877 130.183 1.00 23.86  ? 578  PRO A CG    1 
ATOM   3509  C  CD    . PRO A 1 560  ? 124.765 152.681 130.680 1.00 23.86  ? 578  PRO A CD    1 
ATOM   3510  N  N     . ARG A 1 561  ? 121.041 155.471 130.814 1.00 32.03  ? 579  ARG A N     1 
ATOM   3511  C  CA    . ARG A 1 561  ? 120.331 156.372 131.710 1.00 32.03  ? 579  ARG A CA    1 
ATOM   3512  C  C     . ARG A 1 561  ? 120.070 155.699 133.030 1.00 32.03  ? 579  ARG A C     1 
ATOM   3513  O  O     . ARG A 1 561  ? 119.533 154.595 133.075 1.00 32.03  ? 579  ARG A O     1 
ATOM   3514  C  CB    . ARG A 1 561  ? 119.000 156.791 131.098 1.00 32.03  ? 579  ARG A CB    1 
ATOM   3515  C  CG    . ARG A 1 561  ? 119.111 157.846 130.014 1.00 32.03  ? 579  ARG A CG    1 
ATOM   3516  C  CD    . ARG A 1 561  ? 119.369 159.217 130.613 1.00 32.03  ? 579  ARG A CD    1 
ATOM   3517  N  NE    . ARG A 1 561  ? 118.408 159.534 131.666 1.00 32.03  ? 579  ARG A NE    1 
ATOM   3518  C  CZ    . ARG A 1 561  ? 118.298 160.726 132.241 1.00 32.03  ? 579  ARG A CZ    1 
ATOM   3519  N  NH1   . ARG A 1 561  ? 119.079 161.724 131.856 1.00 32.03  ? 579  ARG A NH1   1 
ATOM   3520  N  NH2   . ARG A 1 561  ? 117.399 160.925 133.193 1.00 32.03  ? 579  ARG A NH2   1 
ATOM   3521  N  N     . LEU A 1 562  ? 120.439 156.367 134.114 1.00 32.52  ? 580  LEU A N     1 
ATOM   3522  C  CA    . LEU A 1 562  ? 120.226 155.809 135.443 1.00 32.52  ? 580  LEU A CA    1 
ATOM   3523  C  C     . LEU A 1 562  ? 118.773 155.410 135.694 1.00 32.52  ? 580  LEU A C     1 
ATOM   3524  O  O     . LEU A 1 562  ? 118.507 154.566 136.546 1.00 32.52  ? 580  LEU A O     1 
ATOM   3525  C  CB    . LEU A 1 562  ? 120.690 156.809 136.501 1.00 32.52  ? 580  LEU A CB    1 
ATOM   3526  C  CG    . LEU A 1 562  ? 121.687 156.254 137.518 1.00 32.52  ? 580  LEU A CG    1 
ATOM   3527  C  CD1   . LEU A 1 562  ? 122.356 157.372 138.300 1.00 32.52  ? 580  LEU A CD1   1 
ATOM   3528  C  CD2   . LEU A 1 562  ? 121.022 155.255 138.450 1.00 32.52  ? 580  LEU A CD2   1 
ATOM   3529  N  N     . ASP A 1 563  ? 117.836 155.994 134.957 1.00 38.59  ? 581  ASP A N     1 
ATOM   3530  C  CA    . ASP A 1 563  ? 116.408 155.729 135.190 1.00 38.59  ? 581  ASP A CA    1 
ATOM   3531  C  C     . ASP A 1 563  ? 115.813 154.663 134.283 1.00 38.59  ? 581  ASP A C     1 
ATOM   3532  O  O     . ASP A 1 563  ? 114.630 154.347 134.390 1.00 38.59  ? 581  ASP A O     1 
ATOM   3533  C  CB    . ASP A 1 563  ? 115.624 157.026 135.015 1.00 38.59  ? 581  ASP A CB    1 
ATOM   3534  C  CG    . ASP A 1 563  ? 115.943 157.724 133.708 1.00 38.59  ? 581  ASP A CG    1 
ATOM   3535  O  OD1   . ASP A 1 563  ? 116.437 157.056 132.778 1.00 38.59  ? 581  ASP A OD1   1 
ATOM   3536  O  OD2   . ASP A 1 563  ? 115.698 158.943 133.610 1.00 38.59  ? 581  ASP A OD2   1 
ATOM   3537  N  N     . ASP A 1 564  ? 116.619 154.105 133.393 1.00 40.53  ? 582  ASP A N     1 
ATOM   3538  C  CA    . ASP A 1 564  ? 116.145 153.106 132.450 1.00 40.53  ? 582  ASP A CA    1 
ATOM   3539  C  C     . ASP A 1 564  ? 115.762 151.816 133.175 1.00 40.53  ? 582  ASP A C     1 
ATOM   3540  O  O     . ASP A 1 564  ? 116.381 151.448 134.177 1.00 40.53  ? 582  ASP A O     1 
ATOM   3541  C  CB    . ASP A 1 564  ? 117.212 152.806 131.401 1.00 40.53  ? 582  ASP A CB    1 
ATOM   3542  C  CG    . ASP A 1 564  ? 117.314 153.888 130.348 1.00 40.53  ? 582  ASP A CG    1 
ATOM   3543  O  OD1   . ASP A 1 564  ? 116.487 154.823 130.372 1.00 40.53  ? 582  ASP A OD1   1 
ATOM   3544  O  OD2   . ASP A 1 564  ? 118.221 153.805 129.493 1.00 40.53  ? 582  ASP A OD2   1 
ATOM   3545  N  N     . PRO A 1 565  ? 114.737 151.111 132.688 1.00 46.09  ? 583  PRO A N     1 
ATOM   3546  C  CA    . PRO A 1 565  ? 114.395 149.805 133.273 1.00 46.09  ? 583  PRO A CA    1 
ATOM   3547  C  C     . PRO A 1 565  ? 115.367 148.698 132.902 1.00 46.09  ? 583  PRO A C     1 
ATOM   3548  O  O     . PRO A 1 565  ? 115.255 147.594 133.451 1.00 46.09  ? 583  PRO A O     1 
ATOM   3549  C  CB    . PRO A 1 565  ? 112.997 149.526 132.709 1.00 46.09  ? 583  PRO A CB    1 
ATOM   3550  C  CG    . PRO A 1 565  ? 112.972 150.265 131.415 1.00 46.09  ? 583  PRO A CG    1 
ATOM   3551  C  CD    . PRO A 1 565  ? 113.793 151.509 131.630 1.00 46.09  ? 583  PRO A CD    1 
ATOM   3552  N  N     . ALA A 1 566  ? 116.307 148.953 131.997 1.00 38.75  ? 584  ALA A N     1 
ATOM   3553  C  CA    . ALA A 1 566  ? 117.311 147.981 131.578 1.00 38.75  ? 584  ALA A CA    1 
ATOM   3554  C  C     . ALA A 1 566  ? 118.705 148.576 131.717 1.00 38.75  ? 584  ALA A C     1 
ATOM   3555  O  O     . ALA A 1 566  ? 119.552 148.469 130.829 1.00 38.75  ? 584  ALA A O     1 
ATOM   3556  C  CB    . ALA A 1 566  ? 117.061 147.517 130.146 1.00 38.75  ? 584  ALA A CB    1 
ATOM   3557  N  N     . TRP A 1 567  ? 118.953 149.223 132.851 1.00 23.91  ? 585  TRP A N     1 
ATOM   3558  C  CA    . TRP A 1 567  ? 120.234 149.865 133.095 1.00 23.91  ? 585  TRP A CA    1 
ATOM   3559  C  C     . TRP A 1 567  ? 121.254 148.859 133.607 1.00 23.91  ? 585  TRP A C     1 
ATOM   3560  O  O     . TRP A 1 567  ? 120.942 148.001 134.438 1.00 23.91  ? 585  TRP A O     1 
ATOM   3561  C  CB    . TRP A 1 567  ? 120.070 151.003 134.102 1.00 23.91  ? 585  TRP A CB    1 
ATOM   3562  C  CG    . TRP A 1 567  ? 121.351 151.512 134.675 1.00 23.91  ? 585  TRP A CG    1 
ATOM   3563  C  CD1   . TRP A 1 567  ? 122.131 152.511 134.179 1.00 23.91  ? 585  TRP A CD1   1 
ATOM   3564  C  CD2   . TRP A 1 567  ? 121.992 151.057 135.870 1.00 23.91  ? 585  TRP A CD2   1 
ATOM   3565  N  NE1   . TRP A 1 567  ? 123.225 152.703 134.988 1.00 23.91  ? 585  TRP A NE1   1 
ATOM   3566  C  CE2   . TRP A 1 567  ? 123.162 151.821 136.033 1.00 23.91  ? 585  TRP A CE2   1 
ATOM   3567  C  CE3   . TRP A 1 567  ? 121.693 150.073 136.815 1.00 23.91  ? 585  TRP A CE3   1 
ATOM   3568  C  CZ2   . TRP A 1 567  ? 124.031 151.634 137.103 1.00 23.91  ? 585  TRP A CZ2   1 
ATOM   3569  C  CZ3   . TRP A 1 567  ? 122.556 149.889 137.874 1.00 23.91  ? 585  TRP A CZ3   1 
ATOM   3570  C  CH2   . TRP A 1 567  ? 123.711 150.664 138.011 1.00 23.91  ? 585  TRP A CH2   1 
ATOM   3571  N  N     . THR A 1 568  ? 122.488 148.983 133.103 1.00 23.07  ? 586  THR A N     1 
ATOM   3572  C  CA    . THR A 1 568  ? 123.598 148.137 133.552 1.00 23.07  ? 586  THR A CA    1 
ATOM   3573  C  C     . THR A 1 568  ? 124.758 149.111 133.780 1.00 23.07  ? 586  THR A C     1 
ATOM   3574  O  O     . THR A 1 568  ? 124.843 150.123 133.098 1.00 23.07  ? 586  THR A O     1 
ATOM   3575  C  CB    . THR A 1 568  ? 123.906 147.016 132.563 1.00 23.07  ? 586  THR A CB    1 
ATOM   3576  O  OG1   . THR A 1 568  ? 123.726 147.500 131.229 1.00 23.07  ? 586  THR A OG1   1 
ATOM   3577  C  CG2   . THR A 1 568  ? 122.970 145.847 132.791 1.00 23.07  ? 586  THR A CG2   1 
ATOM   3578  N  N     . PRO A 1 569  ? 125.664 148.823 134.723 1.00 21.21  ? 587  PRO A N     1 
ATOM   3579  C  CA    . PRO A 1 569  ? 126.685 149.799 135.108 1.00 21.21  ? 587  PRO A CA    1 
ATOM   3580  C  C     . PRO A 1 569  ? 127.836 149.860 134.120 1.00 21.21  ? 587  PRO A C     1 
ATOM   3581  O  O     . PRO A 1 569  ? 128.072 148.946 133.328 1.00 21.21  ? 587  PRO A O     1 
ATOM   3582  C  CB    . PRO A 1 569  ? 127.160 149.287 136.468 1.00 21.21  ? 587  PRO A CB    1 
ATOM   3583  C  CG    . PRO A 1 569  ? 126.940 147.826 136.398 1.00 21.21  ? 587  PRO A CG    1 
ATOM   3584  C  CD    . PRO A 1 569  ? 125.687 147.637 135.594 1.00 21.21  ? 587  PRO A CD    1 
ATOM   3585  N  N     . GLY A 1 570  ? 128.570 150.966 134.194 1.00 27.60  ? 588  GLY A N     1 
ATOM   3586  C  CA    . GLY A 1 570  ? 129.711 151.179 133.339 1.00 27.60  ? 588  GLY A CA    1 
ATOM   3587  C  C     . GLY A 1 570  ? 129.279 151.585 131.950 1.00 27.60  ? 588  GLY A C     1 
ATOM   3588  O  O     . GLY A 1 570  ? 128.089 151.769 131.678 1.00 27.60  ? 588  GLY A O     1 
ATOM   3589  N  N     . PRO A 1 571  ? 130.231 151.738 131.042 1.00 38.40  ? 589  PRO A N     1 
ATOM   3590  C  CA    . PRO A 1 571  ? 129.874 152.092 129.664 1.00 38.40  ? 589  PRO A CA    1 
ATOM   3591  C  C     . PRO A 1 571  ? 129.184 150.948 128.947 1.00 38.40  ? 589  PRO A C     1 
ATOM   3592  O  O     . PRO A 1 571  ? 129.743 150.360 128.019 1.00 38.40  ? 589  PRO A O     1 
ATOM   3593  C  CB    . PRO A 1 571  ? 131.228 152.416 129.025 1.00 38.40  ? 589  PRO A CB    1 
ATOM   3594  C  CG    . PRO A 1 571  ? 132.112 152.745 130.166 1.00 38.40  ? 589  PRO A CG    1 
ATOM   3595  C  CD    . PRO A 1 571  ? 131.675 151.852 131.277 1.00 38.40  ? 589  PRO A CD    1 
ATOM   3596  N  N     . SER A 1 572  ? 127.958 150.630 129.362 1.00 23.99  ? 590  SER A N     1 
ATOM   3597  C  CA    . SER A 1 572  ? 127.309 149.426 128.864 1.00 23.99  ? 590  SER A CA    1 
ATOM   3598  C  C     . SER A 1 572  ? 126.809 149.561 127.434 1.00 23.99  ? 590  SER A C     1 
ATOM   3599  O  O     . SER A 1 572  ? 126.351 148.565 126.868 1.00 23.99  ? 590  SER A O     1 
ATOM   3600  C  CB    . SER A 1 572  ? 126.148 149.040 129.773 1.00 23.99  ? 590  SER A CB    1 
ATOM   3601  O  OG    . SER A 1 572  ? 125.683 147.744 129.449 1.00 23.99  ? 590  SER A OG    1 
ATOM   3602  N  N     . LEU A 1 573  ? 126.875 150.749 126.841 1.00 38.40  ? 591  LEU A N     1 
ATOM   3603  C  CA    . LEU A 1 573  ? 126.492 150.931 125.448 1.00 38.40  ? 591  LEU A CA    1 
ATOM   3604  C  C     . LEU A 1 573  ? 127.686 150.994 124.508 1.00 38.40  ? 591  LEU A C     1 
ATOM   3605  O  O     . LEU A 1 573  ? 127.498 151.192 123.306 1.00 38.40  ? 591  LEU A O     1 
ATOM   3606  C  CB    . LEU A 1 573  ? 125.647 152.198 125.287 1.00 38.40  ? 591  LEU A CB    1 
ATOM   3607  C  CG    . LEU A 1 573  ? 124.357 152.275 126.103 1.00 38.40  ? 591  LEU A CG    1 
ATOM   3608  C  CD1   . LEU A 1 573  ? 123.597 153.547 125.777 1.00 38.40  ? 591  LEU A CD1   1 
ATOM   3609  C  CD2   . LEU A 1 573  ? 123.494 151.051 125.861 1.00 38.40  ? 591  LEU A CD2   1 
ATOM   3610  N  N     . LEU A 1 574  ? 128.901 150.830 125.020 1.00 20.61  ? 592  LEU A N     1 
ATOM   3611  C  CA    . LEU A 1 574  ? 130.084 150.895 124.173 1.00 20.61  ? 592  LEU A CA    1 
ATOM   3612  C  C     . LEU A 1 574  ? 130.128 149.701 123.227 1.00 20.61  ? 592  LEU A C     1 
ATOM   3613  O  O     . LEU A 1 574  ? 129.731 148.589 123.584 1.00 20.61  ? 592  LEU A O     1 
ATOM   3614  C  CB    . LEU A 1 574  ? 131.343 150.940 125.034 1.00 20.61  ? 592  LEU A CB    1 
ATOM   3615  C  CG    . LEU A 1 574  ? 132.682 151.185 124.347 1.00 20.61  ? 592  LEU A CG    1 
ATOM   3616  C  CD1   . LEU A 1 574  ? 132.653 152.465 123.538 1.00 20.61  ? 592  LEU A CD1   1 
ATOM   3617  C  CD2   . LEU A 1 574  ? 133.771 151.244 125.391 1.00 20.61  ? 592  LEU A CD2   1 
ATOM   3618  N  N     . SER A 1 575  ? 130.616 149.941 122.012 1.00 22.99  ? 593  SER A N     1 
ATOM   3619  C  CA    . SER A 1 575  ? 130.657 148.917 120.978 1.00 22.99  ? 593  SER A CA    1 
ATOM   3620  C  C     . SER A 1 575  ? 131.801 149.218 120.021 1.00 22.99  ? 593  SER A C     1 
ATOM   3621  O  O     . SER A 1 575  ? 132.405 150.292 120.058 1.00 22.99  ? 593  SER A O     1 
ATOM   3622  C  CB    . SER A 1 575  ? 129.329 148.831 120.225 1.00 22.99  ? 593  SER A CB    1 
ATOM   3623  O  OG    . SER A 1 575  ? 129.001 150.085 119.656 1.00 22.99  ? 593  SER A OG    1 
ATOM   3624  N  N     . LEU A 1 576  ? 132.094 148.243 119.158 1.00 20.90  ? 594  LEU A N     1 
ATOM   3625  C  CA    . LEU A 1 576  ? 133.207 148.373 118.223 1.00 20.90  ? 594  LEU A CA    1 
ATOM   3626  C  C     . LEU A 1 576  ? 132.942 149.447 117.175 1.00 20.90  ? 594  LEU A C     1 
ATOM   3627  O  O     . LEU A 1 576  ? 133.866 150.157 116.759 1.00 20.90  ? 594  LEU A O     1 
ATOM   3628  C  CB    . LEU A 1 576  ? 133.472 147.031 117.540 1.00 20.90  ? 594  LEU A CB    1 
ATOM   3629  C  CG    . LEU A 1 576  ? 134.449 146.048 118.177 1.00 20.90  ? 594  LEU A CG    1 
ATOM   3630  C  CD1   . LEU A 1 576  ? 134.295 144.684 117.534 1.00 20.90  ? 594  LEU A CD1   1 
ATOM   3631  C  CD2   . LEU A 1 576  ? 135.861 146.551 118.005 1.00 20.90  ? 594  LEU A CD2   1 
ATOM   3632  N  N     . GLN A 1 577  ? 131.692 149.577 116.732 1.00 28.09  ? 595  GLN A N     1 
ATOM   3633  C  CA    . GLN A 1 577  ? 131.386 150.435 115.594 1.00 28.09  ? 595  GLN A CA    1 
ATOM   3634  C  C     . GLN A 1 577  ? 131.442 151.916 115.937 1.00 28.09  ? 595  GLN A C     1 
ATOM   3635  O  O     . GLN A 1 577  ? 131.528 152.744 115.024 1.00 28.09  ? 595  GLN A O     1 
ATOM   3636  C  CB    . GLN A 1 577  ? 130.009 150.089 115.031 1.00 28.09  ? 595  GLN A CB    1 
ATOM   3637  C  CG    . GLN A 1 577  ? 129.930 148.718 114.383 1.00 28.09  ? 595  GLN A CG    1 
ATOM   3638  C  CD    . GLN A 1 577  ? 129.863 147.594 115.393 1.00 28.09  ? 595  GLN A CD    1 
ATOM   3639  O  OE1   . GLN A 1 577  ? 129.673 147.828 116.586 1.00 28.09  ? 595  GLN A OE1   1 
ATOM   3640  N  NE2   . GLN A 1 577  ? 130.020 146.364 114.921 1.00 28.09  ? 595  GLN A NE2   1 
ATOM   3641  N  N     . MET A 1 578  ? 131.392 152.270 117.217 1.00 24.86  ? 596  MET A N     1 
ATOM   3642  C  CA    . MET A 1 578  ? 131.435 153.671 117.598 1.00 24.86  ? 596  MET A CA    1 
ATOM   3643  C  C     . MET A 1 578  ? 132.783 154.285 117.240 1.00 24.86  ? 596  MET A C     1 
ATOM   3644  O  O     . MET A 1 578  ? 133.799 153.599 117.120 1.00 24.86  ? 596  MET A O     1 
ATOM   3645  C  CB    . MET A 1 578  ? 131.175 153.829 119.094 1.00 24.86  ? 596  MET A CB    1 
ATOM   3646  C  CG    . MET A 1 578  ? 129.804 153.368 119.538 1.00 24.86  ? 596  MET A CG    1 
ATOM   3647  S  SD    . MET A 1 578  ? 129.385 153.962 121.185 1.00 24.86  ? 596  MET A SD    1 
ATOM   3648  C  CE    . MET A 1 578  ? 127.624 153.643 121.211 1.00 24.86  ? 596  MET A CE    1 
ATOM   3649  N  N     . ARG A 1 579  ? 132.783 155.605 117.079 1.00 31.76  ? 597  ARG A N     1 
ATOM   3650  C  CA    . ARG A 1 579  ? 134.004 156.347 116.796 1.00 31.76  ? 597  ARG A CA    1 
ATOM   3651  C  C     . ARG A 1 579  ? 134.895 156.499 118.019 1.00 31.76  ? 597  ARG A C     1 
ATOM   3652  O  O     . ARG A 1 579  ? 135.857 157.272 117.978 1.00 31.76  ? 597  ARG A O     1 
ATOM   3653  C  CB    . ARG A 1 579  ? 133.663 157.729 116.236 1.00 31.76  ? 597  ARG A CB    1 
ATOM   3654  C  CG    . ARG A 1 579  ? 132.869 157.694 114.945 1.00 31.76  ? 597  ARG A CG    1 
ATOM   3655  C  CD    . ARG A 1 579  ? 132.574 159.098 114.449 1.00 31.76  ? 597  ARG A CD    1 
ATOM   3656  N  NE    . ARG A 1 579  ? 131.737 159.090 113.257 1.00 31.76  ? 597  ARG A NE    1 
ATOM   3657  C  CZ    . ARG A 1 579  ? 131.311 160.181 112.637 1.00 31.76  ? 597  ARG A CZ    1 
ATOM   3658  N  NH1   . ARG A 1 579  ? 131.631 161.390 113.068 1.00 31.76  ? 597  ARG A NH1   1 
ATOM   3659  N  NH2   . ARG A 1 579  ? 130.547 160.057 111.556 1.00 31.76  ? 597  ARG A NH2   1 
ATOM   3660  N  N     . VAL A 1 580  ? 134.591 155.789 119.102 1.00 38.40  ? 598  VAL A N     1 
ATOM   3661  C  CA    . VAL A 1 580  ? 135.375 155.841 120.323 1.00 38.40  ? 598  VAL A CA    1 
ATOM   3662  C  C     . VAL A 1 580  ? 136.272 154.620 120.466 1.00 38.40  ? 598  VAL A C     1 
ATOM   3663  O  O     . VAL A 1 580  ? 137.426 154.742 120.882 1.00 38.40  ? 598  VAL A O     1 
ATOM   3664  C  CB    . VAL A 1 580  ? 134.457 155.993 121.554 1.00 38.40  ? 598  VAL A CB    1 
ATOM   3665  C  CG1   . VAL A 1 580  ? 133.718 157.316 121.499 1.00 38.40  ? 598  VAL A CG1   1 
ATOM   3666  C  CG2   . VAL A 1 580  ? 133.488 154.829 121.640 1.00 38.40  ? 598  VAL A CG2   1 
ATOM   3667  N  N     . THR A 1 581  ? 135.756 153.438 120.139 1.00 22.05  ? 599  THR A N     1 
ATOM   3668  C  CA    . THR A 1 581  ? 136.441 152.174 120.379 1.00 22.05  ? 599  THR A CA    1 
ATOM   3669  C  C     . THR A 1 581  ? 137.845 152.142 119.776 1.00 22.05  ? 599  THR A C     1 
ATOM   3670  O  O     . THR A 1 581  ? 138.788 151.749 120.474 1.00 22.05  ? 599  THR A O     1 
ATOM   3671  C  CB    . THR A 1 581  ? 135.599 151.009 119.854 1.00 22.05  ? 599  THR A CB    1 
ATOM   3672  O  OG1   . THR A 1 581  ? 134.447 150.838 120.684 1.00 22.05  ? 599  THR A OG1   1 
ATOM   3673  C  CG2   . THR A 1 581  ? 136.406 149.732 119.845 1.00 22.05  ? 599  THR A CG2   1 
ATOM   3674  N  N     . PRO A 1 582  ? 138.055 152.557 118.510 1.00 17.30  ? 600  PRO A N     1 
ATOM   3675  C  CA    . PRO A 1 582  ? 139.430 152.587 117.989 1.00 17.30  ? 600  PRO A CA    1 
ATOM   3676  C  C     . PRO A 1 582  ? 140.274 153.707 118.577 1.00 17.30  ? 600  PRO A C     1 
ATOM   3677  O  O     . PRO A 1 582  ? 141.403 153.935 118.136 1.00 17.30  ? 600  PRO A O     1 
ATOM   3678  C  CB    . PRO A 1 582  ? 139.234 152.764 116.480 1.00 17.30  ? 600  PRO A CB    1 
ATOM   3679  C  CG    . PRO A 1 582  ? 137.913 153.351 116.340 1.00 17.30  ? 600  PRO A CG    1 
ATOM   3680  C  CD    . PRO A 1 582  ? 137.078 152.806 117.436 1.00 17.30  ? 600  PRO A CD    1 
ATOM   3681  N  N     . LYS A 1 583  ? 139.736 154.419 119.565 1.00 22.03  ? 601  LYS A N     1 
ATOM   3682  C  CA    . LYS A 1 583  ? 140.524 155.327 120.385 1.00 22.03  ? 601  LYS A CA    1 
ATOM   3683  C  C     . LYS A 1 583  ? 140.757 154.802 121.788 1.00 22.03  ? 601  LYS A C     1 
ATOM   3684  O  O     . LYS A 1 583  ? 141.787 155.111 122.388 1.00 22.03  ? 601  LYS A O     1 
ATOM   3685  C  CB    . LYS A 1 583  ? 139.841 156.697 120.479 1.00 22.03  ? 601  LYS A CB    1 
ATOM   3686  C  CG    . LYS A 1 583  ? 139.716 157.408 119.154 1.00 22.03  ? 601  LYS A CG    1 
ATOM   3687  C  CD    . LYS A 1 583  ? 138.826 158.623 119.276 1.00 22.03  ? 601  LYS A CD    1 
ATOM   3688  C  CE    . LYS A 1 583  ? 138.807 159.418 117.988 1.00 22.03  ? 601  LYS A CE    1 
ATOM   3689  N  NZ    . LYS A 1 583  ? 137.939 160.617 118.120 1.00 22.03  ? 601  LYS A NZ    1 
ATOM   3690  N  N     . LEU A 1 584  ? 139.823 154.014 122.320 1.00 38.40  ? 602  LEU A N     1 
ATOM   3691  C  CA    . LEU A 1 584  ? 140.037 153.350 123.599 1.00 38.40  ? 602  LEU A CA    1 
ATOM   3692  C  C     . LEU A 1 584  ? 140.985 152.167 123.456 1.00 38.40  ? 602  LEU A C     1 
ATOM   3693  O  O     . LEU A 1 584  ? 141.782 151.897 124.359 1.00 38.40  ? 602  LEU A O     1 
ATOM   3694  C  CB    . LEU A 1 584  ? 138.702 152.904 124.184 1.00 38.40  ? 602  LEU A CB    1 
ATOM   3695  C  CG    . LEU A 1 584  ? 137.766 154.059 124.523 1.00 38.40  ? 602  LEU A CG    1 
ATOM   3696  C  CD1   . LEU A 1 584  ? 136.487 153.527 125.116 1.00 38.40  ? 602  LEU A CD1   1 
ATOM   3697  C  CD2   . LEU A 1 584  ? 138.445 155.026 125.476 1.00 38.40  ? 602  LEU A CD2   1 
ATOM   3698  N  N     . MET A 1 585  ? 140.904 151.444 122.336 1.00 18.93  ? 603  MET A N     1 
ATOM   3699  C  CA    . MET A 1 585  ? 141.907 150.433 122.031 1.00 18.93  ? 603  MET A CA    1 
ATOM   3700  C  C     . MET A 1 585  ? 143.258 151.047 121.711 1.00 18.93  ? 603  MET A C     1 
ATOM   3701  O  O     . MET A 1 585  ? 144.262 150.330 121.703 1.00 18.93  ? 603  MET A O     1 
ATOM   3702  C  CB    . MET A 1 585  ? 141.469 149.576 120.849 1.00 18.93  ? 603  MET A CB    1 
ATOM   3703  C  CG    . MET A 1 585  ? 140.305 148.670 121.118 1.00 18.93  ? 603  MET A CG    1 
ATOM   3704  S  SD    . MET A 1 585  ? 140.074 147.588 119.708 1.00 18.93  ? 603  MET A SD    1 
ATOM   3705  C  CE    . MET A 1 585  ? 138.588 146.734 120.191 1.00 18.93  ? 603  MET A CE    1 
ATOM   3706  N  N     . ALA A 1 586  ? 143.297 152.350 121.442 1.00 19.48  ? 604  ALA A N     1 
ATOM   3707  C  CA    . ALA A 1 586  ? 144.513 153.036 121.018 1.00 19.48  ? 604  ALA A CA    1 
ATOM   3708  C  C     . ALA A 1 586  ? 145.105 152.382 119.775 1.00 19.48  ? 604  ALA A C     1 
ATOM   3709  O  O     . ALA A 1 586  ? 146.318 152.191 119.673 1.00 19.48  ? 604  ALA A O     1 
ATOM   3710  C  CB    . ALA A 1 586  ? 145.541 153.093 122.148 1.00 19.48  ? 604  ALA A CB    1 
ATOM   3711  N  N     . LEU A 1 587  ? 144.238 152.035 118.823 1.00 18.69  ? 605  LEU A N     1 
ATOM   3712  C  CA    . LEU A 1 587  ? 144.679 151.323 117.631 1.00 18.69  ? 605  LEU A CA    1 
ATOM   3713  C  C     . LEU A 1 587  ? 145.771 152.096 116.913 1.00 18.69  ? 605  LEU A C     1 
ATOM   3714  O  O     . LEU A 1 587  ? 145.692 153.317 116.753 1.00 18.69  ? 605  LEU A O     1 
ATOM   3715  C  CB    . LEU A 1 587  ? 143.510 151.083 116.679 1.00 18.69  ? 605  LEU A CB    1 
ATOM   3716  C  CG    . LEU A 1 587  ? 142.581 149.920 117.006 1.00 18.69  ? 605  LEU A CG    1 
ATOM   3717  C  CD1   . LEU A 1 587  ? 141.831 149.496 115.766 1.00 18.69  ? 605  LEU A CD1   1 
ATOM   3718  C  CD2   . LEU A 1 587  ? 143.370 148.765 117.572 1.00 18.69  ? 605  LEU A CD2   1 
ATOM   3719  N  N     . THR A 1 588  ? 146.810 151.377 116.502 1.00 27.05  ? 606  THR A N     1 
ATOM   3720  C  CA    . THR A 1 588  ? 147.908 151.945 115.735 1.00 27.05  ? 606  THR A CA    1 
ATOM   3721  C  C     . THR A 1 588  ? 147.997 151.207 114.410 1.00 27.05  ? 606  THR A C     1 
ATOM   3722  O  O     . THR A 1 588  ? 148.064 149.974 114.386 1.00 27.05  ? 606  THR A O     1 
ATOM   3723  C  CB    . THR A 1 588  ? 149.231 151.840 116.495 1.00 27.05  ? 606  THR A CB    1 
ATOM   3724  O  OG1   . THR A 1 588  ? 149.564 150.461 116.686 1.00 27.05  ? 606  THR A OG1   1 
ATOM   3725  C  CG2   . THR A 1 588  ? 149.122 152.516 117.850 1.00 27.05  ? 606  THR A CG2   1 
ATOM   3726  N  N     . TRP A 1 589  ? 147.989 151.957 113.314 1.00 37.93  ? 607  TRP A N     1 
ATOM   3727  C  CA    . TRP A 1 589  ? 148.220 151.397 111.988 1.00 37.93  ? 607  TRP A CA    1 
ATOM   3728  C  C     . TRP A 1 589  ? 149.682 151.632 111.634 1.00 37.93  ? 607  TRP A C     1 
ATOM   3729  O  O     . TRP A 1 589  ? 150.086 152.770 111.376 1.00 37.93  ? 607  TRP A O     1 
ATOM   3730  C  CB    . TRP A 1 589  ? 147.288 152.035 110.961 1.00 37.93  ? 607  TRP A CB    1 
ATOM   3731  C  CG    . TRP A 1 589  ? 147.540 151.594 109.549 1.00 37.93  ? 607  TRP A CG    1 
ATOM   3732  C  CD1   . TRP A 1 589  ? 148.561 151.989 108.734 1.00 37.93  ? 607  TRP A CD1   1 
ATOM   3733  C  CD2   . TRP A 1 589  ? 146.742 150.691 108.779 1.00 37.93  ? 607  TRP A CD2   1 
ATOM   3734  N  NE1   . TRP A 1 589  ? 148.453 151.379 107.509 1.00 37.93  ? 607  TRP A NE1   1 
ATOM   3735  C  CE2   . TRP A 1 589  ? 147.343 150.578 107.511 1.00 37.93  ? 607  TRP A CE2   1 
ATOM   3736  C  CE3   . TRP A 1 589  ? 145.578 149.964 109.040 1.00 37.93  ? 607  TRP A CE3   1 
ATOM   3737  C  CZ2   . TRP A 1 589  ? 146.820 149.769 106.509 1.00 37.93  ? 607  TRP A CZ2   1 
ATOM   3738  C  CZ3   . TRP A 1 589  ? 145.063 149.162 108.046 1.00 37.93  ? 607  TRP A CZ3   1 
ATOM   3739  C  CH2   . TRP A 1 589  ? 145.682 149.072 106.795 1.00 37.93  ? 607  TRP A CH2   1 
ATOM   3740  N  N     . ASP A 1 590  ? 150.468 150.555 111.612 1.00 45.75  ? 608  ASP A N     1 
ATOM   3741  C  CA    . ASP A 1 590  ? 151.912 150.645 111.397 1.00 45.75  ? 608  ASP A CA    1 
ATOM   3742  C  C     . ASP A 1 590  ? 152.547 151.596 112.409 1.00 45.75  ? 608  ASP A C     1 
ATOM   3743  O  O     . ASP A 1 590  ? 153.389 152.431 112.073 1.00 45.75  ? 608  ASP A O     1 
ATOM   3744  C  CB    . ASP A 1 590  ? 152.227 151.073 109.960 1.00 45.75  ? 608  ASP A CB    1 
ATOM   3745  C  CG    . ASP A 1 590  ? 153.675 150.833 109.583 1.00 45.75  ? 608  ASP A CG    1 
ATOM   3746  O  OD1   . ASP A 1 590  ? 154.069 149.655 109.458 1.00 45.75  ? 608  ASP A OD1   1 
ATOM   3747  O  OD2   . ASP A 1 590  ? 154.418 151.823 109.405 1.00 45.75  ? 608  ASP A OD2   1 
ATOM   3748  N  N     . GLY A 1 591  ? 152.127 151.472 113.666 1.00 42.23  ? 609  GLY A N     1 
ATOM   3749  C  CA    . GLY A 1 591  ? 152.625 152.347 114.707 1.00 42.23  ? 609  GLY A CA    1 
ATOM   3750  C  C     . GLY A 1 591  ? 152.095 153.761 114.658 1.00 42.23  ? 609  GLY A C     1 
ATOM   3751  O  O     . GLY A 1 591  ? 152.744 154.671 115.180 1.00 42.23  ? 609  GLY A O     1 
ATOM   3752  N  N     . PHE A 1 592  ? 150.929 153.976 114.050 1.00 39.00  ? 610  PHE A N     1 
ATOM   3753  C  CA    . PHE A 1 592  ? 150.367 155.309 113.892 1.00 39.00  ? 610  PHE A CA    1 
ATOM   3754  C  C     . PHE A 1 592  ? 148.941 155.328 114.431 1.00 39.00  ? 610  PHE A C     1 
ATOM   3755  O  O     . PHE A 1 592  ? 148.106 154.515 114.000 1.00 39.00  ? 610  PHE A O     1 
ATOM   3756  C  CB    . PHE A 1 592  ? 150.389 155.735 112.422 1.00 39.00  ? 610  PHE A CB    1 
ATOM   3757  C  CG    . PHE A 1 592  ? 151.767 155.981 111.887 1.00 39.00  ? 610  PHE A CG    1 
ATOM   3758  C  CD1   . PHE A 1 592  ? 152.745 156.546 112.688 1.00 39.00  ? 610  PHE A CD1   1 
ATOM   3759  C  CD2   . PHE A 1 592  ? 152.087 155.642 110.585 1.00 39.00  ? 610  PHE A CD2   1 
ATOM   3760  C  CE1   . PHE A 1 592  ? 154.016 156.773 112.198 1.00 39.00  ? 610  PHE A CE1   1 
ATOM   3761  C  CE2   . PHE A 1 592  ? 153.355 155.866 110.089 1.00 39.00  ? 610  PHE A CE2   1 
ATOM   3762  C  CZ    . PHE A 1 592  ? 154.321 156.432 110.896 1.00 39.00  ? 610  PHE A CZ    1 
ATOM   3763  N  N     . PRO A 1 593  ? 148.621 156.233 115.355 1.00 25.79  ? 611  PRO A N     1 
ATOM   3764  C  CA    . PRO A 1 593  ? 147.281 156.240 115.953 1.00 25.79  ? 611  PRO A CA    1 
ATOM   3765  C  C     . PRO A 1 593  ? 146.200 156.565 114.936 1.00 25.79  ? 611  PRO A C     1 
ATOM   3766  O  O     . PRO A 1 593  ? 146.406 157.340 114.001 1.00 25.79  ? 611  PRO A O     1 
ATOM   3767  C  CB    . PRO A 1 593  ? 147.381 157.330 117.026 1.00 25.79  ? 611  PRO A CB    1 
ATOM   3768  C  CG    . PRO A 1 593  ? 148.493 158.211 116.564 1.00 25.79  ? 611  PRO A CG    1 
ATOM   3769  C  CD    . PRO A 1 593  ? 149.477 157.300 115.900 1.00 25.79  ? 611  PRO A CD    1 
ATOM   3770  N  N     . LEU A 1 594  ? 145.030 155.966 115.138 1.00 22.13  ? 612  LEU A N     1 
ATOM   3771  C  CA    . LEU A 1 594  ? 143.904 156.167 114.238 1.00 22.13  ? 612  LEU A CA    1 
ATOM   3772  C  C     . LEU A 1 594  ? 143.163 157.453 114.580 1.00 22.13  ? 612  LEU A C     1 
ATOM   3773  O  O     . LEU A 1 594  ? 142.933 157.762 115.751 1.00 22.13  ? 612  LEU A O     1 
ATOM   3774  C  CB    . LEU A 1 594  ? 142.946 154.980 114.310 1.00 22.13  ? 612  LEU A CB    1 
ATOM   3775  C  CG    . LEU A 1 594  ? 143.185 153.826 113.339 1.00 22.13  ? 612  LEU A CG    1 
ATOM   3776  C  CD1   . LEU A 1 594  ? 144.610 153.310 113.430 1.00 22.13  ? 612  LEU A CD1   1 
ATOM   3777  C  CD2   . LEU A 1 594  ? 142.200 152.712 113.612 1.00 22.13  ? 612  LEU A CD2   1 
ATOM   3778  N  N     . HIS A 1 595  ? 142.782 158.198 113.545 1.00 28.85  ? 613  HIS A N     1 
ATOM   3779  C  CA    . HIS A 1 595  ? 142.092 159.469 113.704 1.00 28.85  ? 613  HIS A CA    1 
ATOM   3780  C  C     . HIS A 1 595  ? 140.901 159.528 112.760 1.00 28.85  ? 613  HIS A C     1 
ATOM   3781  O  O     . HIS A 1 595  ? 140.943 158.992 111.650 1.00 28.85  ? 613  HIS A O     1 
ATOM   3782  C  CB    . HIS A 1 595  ? 143.030 160.647 113.434 1.00 28.85  ? 613  HIS A CB    1 
ATOM   3783  C  CG    . HIS A 1 595  ? 142.356 161.981 113.491 1.00 28.85  ? 613  HIS A CG    1 
ATOM   3784  N  ND1   . HIS A 1 595  ? 141.513 162.347 114.517 1.00 28.85  ? 613  HIS A ND1   1 
ATOM   3785  C  CD2   . HIS A 1 595  ? 142.402 163.039 112.647 1.00 28.85  ? 613  HIS A CD2   1 
ATOM   3786  C  CE1   . HIS A 1 595  ? 141.069 163.572 114.305 1.00 28.85  ? 613  HIS A CE1   1 
ATOM   3787  N  NE2   . HIS A 1 595  ? 141.593 164.015 113.176 1.00 28.85  ? 613  HIS A NE2   1 
ATOM   3788  N  N     . TYR A 1 596  ? 139.838 160.190 113.206 1.00 28.80  ? 614  TYR A N     1 
ATOM   3789  C  CA    . TYR A 1 596  ? 138.618 160.315 112.424 1.00 28.80  ? 614  TYR A CA    1 
ATOM   3790  C  C     . TYR A 1 596  ? 138.418 161.758 111.992 1.00 28.80  ? 614  TYR A C     1 
ATOM   3791  O  O     . TYR A 1 596  ? 138.589 162.686 112.789 1.00 28.80  ? 614  TYR A O     1 
ATOM   3792  C  CB    . TYR A 1 596  ? 137.396 159.849 113.213 1.00 28.80  ? 614  TYR A CB    1 
ATOM   3793  C  CG    . TYR A 1 596  ? 136.162 159.632 112.364 1.00 28.80  ? 614  TYR A CG    1 
ATOM   3794  C  CD1   . TYR A 1 596  ? 135.401 160.699 111.910 1.00 28.80  ? 614  TYR A CD1   1 
ATOM   3795  C  CD2   . TYR A 1 596  ? 135.749 158.356 112.030 1.00 28.80  ? 614  TYR A CD2   1 
ATOM   3796  C  CE1   . TYR A 1 596  ? 134.275 160.496 111.138 1.00 28.80  ? 614  TYR A CE1   1 
ATOM   3797  C  CE2   . TYR A 1 596  ? 134.625 158.142 111.265 1.00 28.80  ? 614  TYR A CE2   1 
ATOM   3798  C  CZ    . TYR A 1 596  ? 133.891 159.213 110.821 1.00 28.80  ? 614  TYR A CZ    1 
ATOM   3799  O  OH    . TYR A 1 596  ? 132.770 158.998 110.055 1.00 28.80  ? 614  TYR A OH    1 
ATOM   3800  N  N     . SER A 1 597  ? 138.052 161.938 110.727 1.00 44.04  ? 615  SER A N     1 
ATOM   3801  C  CA    . SER A 1 597  ? 137.667 163.231 110.186 1.00 44.04  ? 615  SER A CA    1 
ATOM   3802  C  C     . SER A 1 597  ? 136.324 163.089 109.486 1.00 44.04  ? 615  SER A C     1 
ATOM   3803  O  O     . SER A 1 597  ? 136.092 162.111 108.770 1.00 44.04  ? 615  SER A O     1 
ATOM   3804  C  CB    . SER A 1 597  ? 138.718 163.767 109.212 1.00 44.04  ? 615  SER A CB    1 
ATOM   3805  O  OG    . SER A 1 597  ? 138.362 165.052 108.734 1.00 44.04  ? 615  SER A OG    1 
ATOM   3806  N  N     . GLU A 1 598  ? 135.440 164.066 109.700 1.00 52.29  ? 616  GLU A N     1 
ATOM   3807  C  CA    . GLU A 1 598  ? 134.119 164.016 109.080 1.00 52.29  ? 616  GLU A CA    1 
ATOM   3808  C  C     . GLU A 1 598  ? 134.221 164.054 107.561 1.00 52.29  ? 616  GLU A C     1 
ATOM   3809  O  O     . GLU A 1 598  ? 133.476 163.358 106.861 1.00 52.29  ? 616  GLU A O     1 
ATOM   3810  C  CB    . GLU A 1 598  ? 133.258 165.176 109.581 1.00 52.29  ? 616  GLU A CB    1 
ATOM   3811  C  CG    . GLU A 1 598  ? 133.000 165.174 111.077 1.00 52.29  ? 616  GLU A CG    1 
ATOM   3812  C  CD    . GLU A 1 598  ? 131.854 164.266 111.474 1.00 52.29  ? 616  GLU A CD    1 
ATOM   3813  O  OE1   . GLU A 1 598  ? 131.274 163.609 110.585 1.00 52.29  ? 616  GLU A OE1   1 
ATOM   3814  O  OE2   . GLU A 1 598  ? 131.528 164.215 112.679 1.00 52.29  ? 616  GLU A OE2   1 
ATOM   3815  N  N     . ARG A 1 599  ? 135.133 164.872 107.035 1.00 57.03  ? 617  ARG A N     1 
ATOM   3816  C  CA    . ARG A 1 599  ? 135.255 165.036 105.591 1.00 57.03  ? 617  ARG A CA    1 
ATOM   3817  C  C     . ARG A 1 599  ? 135.719 163.751 104.914 1.00 57.03  ? 617  ARG A C     1 
ATOM   3818  O  O     . ARG A 1 599  ? 135.200 163.374 103.857 1.00 57.03  ? 617  ARG A O     1 
ATOM   3819  C  CB    . ARG A 1 599  ? 136.220 166.181 105.283 1.00 57.03  ? 617  ARG A CB    1 
ATOM   3820  C  CG    . ARG A 1 599  ? 135.841 167.511 105.919 1.00 57.03  ? 617  ARG A CG    1 
ATOM   3821  C  CD    . ARG A 1 599  ? 134.998 168.368 104.984 1.00 57.03  ? 617  ARG A CD    1 
ATOM   3822  N  NE    . ARG A 1 599  ? 133.729 167.739 104.640 1.00 57.03  ? 617  ARG A NE    1 
ATOM   3823  C  CZ    . ARG A 1 599  ? 132.619 167.851 105.357 1.00 57.03  ? 617  ARG A CZ    1 
ATOM   3824  N  NH1   . ARG A 1 599  ? 132.587 168.555 106.476 1.00 57.03  ? 617  ARG A NH1   1 
ATOM   3825  N  NH2   . ARG A 1 599  ? 131.513 167.241 104.940 1.00 57.03  ? 617  ARG A NH2   1 
ATOM   3826  N  N     . HIS A 1 600  ? 136.693 163.063 105.506 1.00 47.41  ? 618  HIS A N     1 
ATOM   3827  C  CA    . HIS A 1 600  ? 137.400 161.984 104.828 1.00 47.41  ? 618  HIS A CA    1 
ATOM   3828  C  C     . HIS A 1 600  ? 137.119 160.606 105.406 1.00 47.41  ? 618  HIS A C     1 
ATOM   3829  O  O     . HIS A 1 600  ? 136.998 159.638 104.651 1.00 47.41  ? 618  HIS A O     1 
ATOM   3830  C  CB    . HIS A 1 600  ? 138.906 162.268 104.853 1.00 47.41  ? 618  HIS A CB    1 
ATOM   3831  C  CG    . HIS A 1 600  ? 139.271 163.603 104.286 1.00 47.41  ? 618  HIS A CG    1 
ATOM   3832  N  ND1   . HIS A 1 600  ? 138.949 163.976 102.999 1.00 47.41  ? 618  HIS A ND1   1 
ATOM   3833  C  CD2   . HIS A 1 600  ? 139.924 164.656 104.831 1.00 47.41  ? 618  HIS A CD2   1 
ATOM   3834  C  CE1   . HIS A 1 600  ? 139.390 165.201 102.775 1.00 47.41  ? 618  HIS A CE1   1 
ATOM   3835  N  NE2   . HIS A 1 600  ? 139.987 165.635 103.870 1.00 47.41  ? 618  HIS A NE2   1 
ATOM   3836  N  N     . GLY A 1 601  ? 137.029 160.479 106.726 1.00 35.49  ? 619  GLY A N     1 
ATOM   3837  C  CA    . GLY A 1 601  ? 136.721 159.204 107.330 1.00 35.49  ? 619  GLY A CA    1 
ATOM   3838  C  C     . GLY A 1 601  ? 137.843 158.755 108.233 1.00 35.49  ? 619  GLY A C     1 
ATOM   3839  O  O     . GLY A 1 601  ? 138.637 159.566 108.721 1.00 35.49  ? 619  GLY A O     1 
ATOM   3840  N  N     . TRP A 1 602  ? 137.908 157.446 108.465 1.00 25.14  ? 620  TRP A N     1 
ATOM   3841  C  CA    . TRP A 1 602  ? 138.905 156.884 109.367 1.00 25.14  ? 620  TRP A CA    1 
ATOM   3842  C  C     . TRP A 1 602  ? 140.268 156.848 108.692 1.00 25.14  ? 620  TRP A C     1 
ATOM   3843  O  O     . TRP A 1 602  ? 140.437 156.206 107.651 1.00 25.14  ? 620  TRP A O     1 
ATOM   3844  C  CB    . TRP A 1 602  ? 138.493 155.487 109.822 1.00 25.14  ? 620  TRP A CB    1 
ATOM   3845  C  CG    . TRP A 1 602  ? 137.778 155.507 111.126 1.00 25.14  ? 620  TRP A CG    1 
ATOM   3846  C  CD1   . TRP A 1 602  ? 136.484 155.149 111.362 1.00 25.14  ? 620  TRP A CD1   1 
ATOM   3847  C  CD2   . TRP A 1 602  ? 138.310 155.938 112.381 1.00 25.14  ? 620  TRP A CD2   1 
ATOM   3848  N  NE1   . TRP A 1 602  ? 136.182 155.316 112.690 1.00 25.14  ? 620  TRP A NE1   1 
ATOM   3849  C  CE2   . TRP A 1 602  ? 137.288 155.801 113.337 1.00 25.14  ? 620  TRP A CE2   1 
ATOM   3850  C  CE3   . TRP A 1 602  ? 139.556 156.420 112.791 1.00 25.14  ? 620  TRP A CE3   1 
ATOM   3851  C  CZ2   . TRP A 1 602  ? 137.470 156.138 114.672 1.00 25.14  ? 620  TRP A CZ2   1 
ATOM   3852  C  CZ3   . TRP A 1 602  ? 139.736 156.745 114.115 1.00 25.14  ? 620  TRP A CZ3   1 
ATOM   3853  C  CH2   . TRP A 1 602  ? 138.701 156.600 115.043 1.00 25.14  ? 620  TRP A CH2   1 
ATOM   3854  N  N     . GLY A 1 603  ? 141.238 157.537 109.284 1.00 25.03  ? 621  GLY A N     1 
ATOM   3855  C  CA    . GLY A 1 603  ? 142.599 157.560 108.803 1.00 25.03  ? 621  GLY A CA    1 
ATOM   3856  C  C     . GLY A 1 603  ? 143.575 157.244 109.920 1.00 25.03  ? 621  GLY A C     1 
ATOM   3857  O  O     . GLY A 1 603  ? 143.278 156.488 110.842 1.00 25.03  ? 621  GLY A O     1 
ATOM   3858  N  N     . TYR A 1 604  ? 144.760 157.837 109.815 1.00 34.16  ? 622  TYR A N     1 
ATOM   3859  C  CA    . TYR A 1 604  ? 145.758 157.722 110.868 1.00 34.16  ? 622  TYR A CA    1 
ATOM   3860  C  C     . TYR A 1 604  ? 146.696 158.913 110.776 1.00 34.16  ? 622  TYR A C     1 
ATOM   3861  O  O     . TYR A 1 604  ? 146.773 159.587 109.747 1.00 34.16  ? 622  TYR A O     1 
ATOM   3862  C  CB    . TYR A 1 604  ? 146.531 156.397 110.787 1.00 34.16  ? 622  TYR A CB    1 
ATOM   3863  C  CG    . TYR A 1 604  ? 147.233 156.131 109.471 1.00 34.16  ? 622  TYR A CG    1 
ATOM   3864  C  CD1   . TYR A 1 604  ? 148.499 156.641 109.217 1.00 34.16  ? 622  TYR A CD1   1 
ATOM   3865  C  CD2   . TYR A 1 604  ? 146.638 155.347 108.493 1.00 34.16  ? 622  TYR A CD2   1 
ATOM   3866  C  CE1   . TYR A 1 604  ? 149.141 156.394 108.020 1.00 34.16  ? 622  TYR A CE1   1 
ATOM   3867  C  CE2   . TYR A 1 604  ? 147.273 155.095 107.295 1.00 34.16  ? 622  TYR A CE2   1 
ATOM   3868  C  CZ    . TYR A 1 604  ? 148.522 155.621 107.064 1.00 34.16  ? 622  TYR A CZ    1 
ATOM   3869  O  OH    . TYR A 1 604  ? 149.155 155.369 105.869 1.00 34.16  ? 622  TYR A OH    1 
ATOM   3870  N  N     . LEU A 1 605  ? 147.400 159.168 111.872 1.00 37.25  ? 623  LEU A N     1 
ATOM   3871  C  CA    . LEU A 1 605  ? 148.300 160.306 111.988 1.00 37.25  ? 623  LEU A CA    1 
ATOM   3872  C  C     . LEU A 1 605  ? 149.723 159.815 112.196 1.00 37.25  ? 623  LEU A C     1 
ATOM   3873  O  O     . LEU A 1 605  ? 149.946 158.785 112.837 1.00 37.25  ? 623  LEU A O     1 
ATOM   3874  C  CB    . LEU A 1 605  ? 147.894 161.217 113.149 1.00 37.25  ? 623  LEU A CB    1 
ATOM   3875  C  CG    . LEU A 1 605  ? 146.469 161.764 113.136 1.00 37.25  ? 623  LEU A CG    1 
ATOM   3876  C  CD1   . LEU A 1 605  ? 146.169 162.502 114.430 1.00 37.25  ? 623  LEU A CD1   1 
ATOM   3877  C  CD2   . LEU A 1 605  ? 146.267 162.676 111.942 1.00 37.25  ? 623  LEU A CD2   1 
ATOM   3878  N  N     . VAL A 1 606  ? 150.683 160.565 111.670 1.00 42.92  ? 624  VAL A N     1 
ATOM   3879  C  CA    . VAL A 1 606  ? 152.086 160.200 111.796 1.00 42.92  ? 624  VAL A CA    1 
ATOM   3880  C  C     . VAL A 1 606  ? 152.737 160.955 112.948 1.00 42.92  ? 624  VAL A C     1 
ATOM   3881  O  O     . VAL A 1 606  ? 153.134 162.110 112.801 1.00 42.92  ? 624  VAL A O     1 
ATOM   3882  C  CB    . VAL A 1 606  ? 152.840 160.455 110.485 1.00 42.92  ? 624  VAL A CB    1 
ATOM   3883  C  CG1   . VAL A 1 606  ? 154.295 160.033 110.621 1.00 42.92  ? 624  VAL A CG1   1 
ATOM   3884  C  CG2   . VAL A 1 606  ? 152.168 159.714 109.343 1.00 42.92  ? 624  VAL A CG2   1 
ATOM   3885  N  N     . ASN A 1 718  ? 146.172 157.387 102.191 1.00 42.24  ? 736  ASN A N     1 
ATOM   3886  C  CA    . ASN A 1 718  ? 145.879 157.811 100.828 1.00 42.24  ? 736  ASN A CA    1 
ATOM   3887  C  C     . ASN A 1 718  ? 146.158 159.295 100.644 1.00 42.24  ? 736  ASN A C     1 
ATOM   3888  O  O     . ASN A 1 718  ? 145.334 160.027 100.096 1.00 42.24  ? 736  ASN A O     1 
ATOM   3889  C  CB    . ASN A 1 718  ? 144.424 157.505 100.467 1.00 42.24  ? 736  ASN A CB    1 
ATOM   3890  C  CG    . ASN A 1 718  ? 144.108 156.027 100.528 1.00 42.24  ? 736  ASN A CG    1 
ATOM   3891  O  OD1   . ASN A 1 718  ? 142.991 155.631 100.862 1.00 42.24  ? 736  ASN A OD1   1 
ATOM   3892  N  ND2   . ASN A 1 718  ? 145.096 155.199 100.214 1.00 42.24  ? 736  ASN A ND2   1 
ATOM   3893  N  N     . GLY A 1 719  ? 147.323 159.736 101.107 1.00 43.77  ? 737  GLY A N     1 
ATOM   3894  C  CA    . GLY A 1 719  ? 147.740 161.105 100.931 1.00 43.77  ? 737  GLY A CA    1 
ATOM   3895  C  C     . GLY A 1 719  ? 147.468 161.969 102.144 1.00 43.77  ? 737  GLY A C     1 
ATOM   3896  O  O     . GLY A 1 719  ? 146.528 161.734 102.909 1.00 43.77  ? 737  GLY A O     1 
ATOM   3897  N  N     . PRO A 1 720  ? 148.301 162.988 102.346 1.00 44.97  ? 738  PRO A N     1 
ATOM   3898  C  CA    . PRO A 1 720  ? 148.143 163.926 103.478 1.00 44.97  ? 738  PRO A CA    1 
ATOM   3899  C  C     . PRO A 1 720  ? 147.102 165.012 103.216 1.00 44.97  ? 738  PRO A C     1 
ATOM   3900  O  O     . PRO A 1 720  ? 147.392 166.126 102.783 1.00 44.97  ? 738  PRO A O     1 
ATOM   3901  C  CB    . PRO A 1 720  ? 149.551 164.507 103.626 1.00 44.97  ? 738  PRO A CB    1 
ATOM   3902  C  CG    . PRO A 1 720  ? 150.102 164.477 102.245 1.00 44.97  ? 738  PRO A CG    1 
ATOM   3903  C  CD    . PRO A 1 720  ? 149.523 163.260 101.571 1.00 44.97  ? 738  PRO A CD    1 
ATOM   3904  N  N     . TYR A 1 721  ? 145.840 164.672 103.473 1.00 48.13  ? 739  TYR A N     1 
ATOM   3905  C  CA    . TYR A 1 721  ? 144.756 165.631 103.300 1.00 48.13  ? 739  TYR A CA    1 
ATOM   3906  C  C     . TYR A 1 721  ? 144.950 166.824 104.228 1.00 48.13  ? 739  TYR A C     1 
ATOM   3907  O  O     . TYR A 1 721  ? 145.268 166.663 105.409 1.00 48.13  ? 739  TYR A O     1 
ATOM   3908  C  CB    . TYR A 1 721  ? 143.410 164.966 103.574 1.00 48.13  ? 739  TYR A CB    1 
ATOM   3909  C  CG    . TYR A 1 721  ? 143.071 163.843 102.624 1.00 48.13  ? 739  TYR A CG    1 
ATOM   3910  C  CD1   . TYR A 1 721  ? 143.563 162.565 102.830 1.00 48.13  ? 739  TYR A CD1   1 
ATOM   3911  C  CD2   . TYR A 1 721  ? 142.251 164.059 101.527 1.00 48.13  ? 739  TYR A CD2   1 
ATOM   3912  C  CE1   . TYR A 1 721  ? 143.257 161.536 101.968 1.00 48.13  ? 739  TYR A CE1   1 
ATOM   3913  C  CE2   . TYR A 1 721  ? 141.936 163.034 100.661 1.00 48.13  ? 739  TYR A CE2   1 
ATOM   3914  C  CZ    . TYR A 1 721  ? 142.442 161.774 100.887 1.00 48.13  ? 739  TYR A CZ    1 
ATOM   3915  O  OH    . TYR A 1 721  ? 142.134 160.745 100.027 1.00 48.13  ? 739  TYR A OH    1 
ATOM   3916  N  N     . ASN A 1 722  ? 144.757 168.023 103.686 1.00 58.91  ? 740  ASN A N     1 
ATOM   3917  C  CA    . ASN A 1 722  ? 144.951 169.254 104.439 1.00 58.91  ? 740  ASN A CA    1 
ATOM   3918  C  C     . ASN A 1 722  ? 143.673 169.771 105.086 1.00 58.91  ? 740  ASN A C     1 
ATOM   3919  O  O     . ASN A 1 722  ? 143.720 170.792 105.780 1.00 58.91  ? 740  ASN A O     1 
ATOM   3920  C  CB    . ASN A 1 722  ? 145.542 170.338 103.533 1.00 58.91  ? 740  ASN A CB    1 
ATOM   3921  C  CG    . ASN A 1 722  ? 146.979 170.053 103.147 1.00 58.91  ? 740  ASN A CG    1 
ATOM   3922  O  OD1   . ASN A 1 722  ? 147.445 168.918 103.238 1.00 58.91  ? 740  ASN A OD1   1 
ATOM   3923  N  ND2   . ASN A 1 722  ? 147.692 171.087 102.716 1.00 58.91  ? 740  ASN A ND2   1 
ATOM   3924  N  N     . ASP A 1 723  ? 142.536 169.106 104.871 1.00 59.50  ? 741  ASP A N     1 
ATOM   3925  C  CA    . ASP A 1 723  ? 141.313 169.503 105.563 1.00 59.50  ? 741  ASP A CA    1 
ATOM   3926  C  C     . ASP A 1 723  ? 141.451 169.309 107.066 1.00 59.50  ? 741  ASP A C     1 
ATOM   3927  O  O     . ASP A 1 723  ? 141.004 170.151 107.854 1.00 59.50  ? 741  ASP A O     1 
ATOM   3928  C  CB    . ASP A 1 723  ? 140.121 168.711 105.028 1.00 59.50  ? 741  ASP A CB    1 
ATOM   3929  C  CG    . ASP A 1 723  ? 139.985 168.809 103.523 1.00 59.50  ? 741  ASP A CG    1 
ATOM   3930  O  OD1   . ASP A 1 723  ? 140.904 169.354 102.877 1.00 59.50  ? 741  ASP A OD1   1 
ATOM   3931  O  OD2   . ASP A 1 723  ? 138.959 168.343 102.987 1.00 59.50  ? 741  ASP A OD2   1 
ATOM   3932  N  N     . VAL A 1 724  ? 142.087 168.205 107.449 1.00 55.93  ? 742  VAL A N     1 
ATOM   3933  C  CA    . VAL A 1 724  ? 142.328 167.936 108.855 1.00 55.93  ? 742  VAL A CA    1 
ATOM   3934  C  C     . VAL A 1 724  ? 143.514 168.779 109.292 1.00 55.93  ? 742  VAL A C     1 
ATOM   3935  O  O     . VAL A 1 724  ? 144.553 168.763 108.637 1.00 55.93  ? 742  VAL A O     1 
ATOM   3936  C  CB    . VAL A 1 724  ? 142.595 166.445 109.084 1.00 55.93  ? 742  VAL A CB    1 
ATOM   3937  C  CG1   . VAL A 1 724  ? 142.510 166.117 110.564 1.00 55.93  ? 742  VAL A CG1   1 
ATOM   3938  C  CG2   . VAL A 1 724  ? 141.596 165.611 108.300 1.00 55.93  ? 742  VAL A CG2   1 
ATOM   3939  N  N     . ASP A 1 725  ? 143.377 169.513 110.388 1.00 59.37  ? 743  ASP A N     1 
ATOM   3940  C  CA    . ASP A 1 725  ? 144.420 170.425 110.846 1.00 59.37  ? 743  ASP A CA    1 
ATOM   3941  C  C     . ASP A 1 725  ? 144.998 170.001 112.194 1.00 59.37  ? 743  ASP A C     1 
ATOM   3942  O  O     . ASP A 1 725  ? 145.244 170.833 113.069 1.00 59.37  ? 743  ASP A O     1 
ATOM   3943  C  CB    . ASP A 1 725  ? 143.889 171.854 110.923 1.00 59.37  ? 743  ASP A CB    1 
ATOM   3944  C  CG    . ASP A 1 725  ? 142.639 171.968 111.775 1.00 59.37  ? 743  ASP A CG    1 
ATOM   3945  O  OD1   . ASP A 1 725  ? 142.115 170.923 112.214 1.00 59.37  ? 743  ASP A OD1   1 
ATOM   3946  O  OD2   . ASP A 1 725  ? 142.180 173.106 112.007 1.00 59.37  ? 743  ASP A OD2   1 
ATOM   3947  N  N     . ILE A 1 726  ? 145.212 168.702 112.377 1.00 58.04  ? 744  ILE A N     1 
ATOM   3948  C  CA    . ILE A 1 726  ? 145.839 168.235 113.618 1.00 58.04  ? 744  ILE A CA    1 
ATOM   3949  C  C     . ILE A 1 726  ? 147.267 168.765 113.679 1.00 58.04  ? 744  ILE A C     1 
ATOM   3950  O  O     . ILE A 1 726  ? 148.027 168.608 112.703 1.00 58.04  ? 744  ILE A O     1 
ATOM   3951  C  CB    . ILE A 1 726  ? 145.815 166.699 113.691 1.00 58.04  ? 744  ILE A CB    1 
ATOM   3952  C  CG1   . ILE A 1 726  ? 144.424 166.170 113.338 1.00 58.04  ? 744  ILE A CG1   1 
ATOM   3953  C  CG2   . ILE A 1 726  ? 146.228 166.225 115.075 1.00 58.04  ? 744  ILE A CG2   1 
ATOM   3954  C  CD1   . ILE A 1 726  ? 143.314 166.738 114.190 1.00 58.04  ? 744  ILE A CD1   1 
ATOM   3955  N  N     . PRO A 1 727  ? 147.681 169.402 114.774 1.00 63.82  ? 745  PRO A N     1 
ATOM   3956  C  CA    . PRO A 1 727  ? 148.996 170.065 114.801 1.00 63.82  ? 745  PRO A CA    1 
ATOM   3957  C  C     . PRO A 1 727  ? 150.142 169.077 114.643 1.00 63.82  ? 745  PRO A C     1 
ATOM   3958  O  O     . PRO A 1 727  ? 150.349 168.195 115.480 1.00 63.82  ? 745  PRO A O     1 
ATOM   3959  C  CB    . PRO A 1 727  ? 149.019 170.740 116.178 1.00 63.82  ? 745  PRO A CB    1 
ATOM   3960  C  CG    . PRO A 1 727  ? 147.581 170.874 116.565 1.00 63.82  ? 745  PRO A CG    1 
ATOM   3961  C  CD    . PRO A 1 727  ? 146.903 169.667 115.995 1.00 63.82  ? 745  PRO A CD    1 
ATOM   3962  N  N     . GLY A 1 728  ? 150.893 169.235 113.554 1.00 68.42  ? 746  GLY A N     1 
ATOM   3963  C  CA    . GLY A 1 728  ? 152.088 168.454 113.317 1.00 68.42  ? 746  GLY A CA    1 
ATOM   3964  C  C     . GLY A 1 728  ? 151.864 167.060 112.775 1.00 68.42  ? 746  GLY A C     1 
ATOM   3965  O  O     . GLY A 1 728  ? 152.842 166.325 112.590 1.00 68.42  ? 746  GLY A O     1 
ATOM   3966  N  N     . CYS A 1 729  ? 150.621 166.670 112.511 1.00 66.97  ? 747  CYS A N     1 
ATOM   3967  C  CA    . CYS A 1 729  ? 150.305 165.334 112.030 1.00 66.97  ? 747  CYS A CA    1 
ATOM   3968  C  C     . CYS A 1 729  ? 149.784 165.392 110.600 1.00 66.97  ? 747  CYS A C     1 
ATOM   3969  O  O     . CYS A 1 729  ? 149.192 166.388 110.174 1.00 66.97  ? 747  CYS A O     1 
ATOM   3970  C  CB    . CYS A 1 729  ? 149.270 164.653 112.930 1.00 66.97  ? 747  CYS A CB    1 
ATOM   3971  S  SG    . CYS A 1 729  ? 149.867 164.259 114.588 1.00 66.97  ? 747  CYS A SG    1 
ATOM   3972  N  N     . TRP A 1 730  ? 150.012 164.309 109.865 1.00 57.50  ? 748  TRP A N     1 
ATOM   3973  C  CA    . TRP A 1 730  ? 149.556 164.167 108.488 1.00 57.50  ? 748  TRP A CA    1 
ATOM   3974  C  C     . TRP A 1 730  ? 148.456 163.118 108.453 1.00 57.50  ? 748  TRP A C     1 
ATOM   3975  O  O     . TRP A 1 730  ? 148.709 161.943 108.740 1.00 57.50  ? 748  TRP A O     1 
ATOM   3976  C  CB    . TRP A 1 730  ? 150.708 163.767 107.568 1.00 57.50  ? 748  TRP A CB    1 
ATOM   3977  C  CG    . TRP A 1 730  ? 151.864 164.710 107.594 1.00 57.50  ? 748  TRP A CG    1 
ATOM   3978  C  CD1   . TRP A 1 730  ? 152.144 165.685 106.684 1.00 57.50  ? 748  TRP A CD1   1 
ATOM   3979  C  CD2   . TRP A 1 730  ? 152.902 164.769 108.578 1.00 57.50  ? 748  TRP A CD2   1 
ATOM   3980  N  NE1   . TRP A 1 730  ? 153.292 166.349 107.040 1.00 57.50  ? 748  TRP A NE1   1 
ATOM   3981  C  CE2   . TRP A 1 730  ? 153.777 165.805 108.200 1.00 57.50  ? 748  TRP A CE2   1 
ATOM   3982  C  CE3   . TRP A 1 730  ? 153.176 164.046 109.743 1.00 57.50  ? 748  TRP A CE3   1 
ATOM   3983  C  CZ2   . TRP A 1 730  ? 154.906 166.137 108.944 1.00 57.50  ? 748  TRP A CZ2   1 
ATOM   3984  C  CZ3   . TRP A 1 730  ? 154.297 164.377 110.480 1.00 57.50  ? 748  TRP A CZ3   1 
ATOM   3985  C  CH2   . TRP A 1 730  ? 155.148 165.413 110.078 1.00 57.50  ? 748  TRP A CH2   1 
ATOM   3986  N  N     . PHE A 1 731  ? 147.245 163.536 108.101 1.00 38.49  ? 749  PHE A N     1 
ATOM   3987  C  CA    . PHE A 1 731  ? 146.099 162.631 108.102 1.00 38.49  ? 749  PHE A CA    1 
ATOM   3988  C  C     . PHE A 1 731  ? 146.110 161.820 106.814 1.00 38.49  ? 749  PHE A C     1 
ATOM   3989  O  O     . PHE A 1 731  ? 145.685 162.299 105.760 1.00 38.49  ? 749  PHE A O     1 
ATOM   3990  C  CB    . PHE A 1 731  ? 144.797 163.410 108.254 1.00 38.49  ? 749  PHE A CB    1 
ATOM   3991  C  CG    . PHE A 1 731  ? 143.569 162.549 108.201 1.00 38.49  ? 749  PHE A CG    1 
ATOM   3992  C  CD1   . PHE A 1 731  ? 143.174 161.818 109.305 1.00 38.49  ? 749  PHE A CD1   1 
ATOM   3993  C  CD2   . PHE A 1 731  ? 142.808 162.474 107.049 1.00 38.49  ? 749  PHE A CD2   1 
ATOM   3994  C  CE1   . PHE A 1 731  ? 142.046 161.027 109.259 1.00 38.49  ? 749  PHE A CE1   1 
ATOM   3995  C  CE2   . PHE A 1 731  ? 141.680 161.686 106.999 1.00 38.49  ? 749  PHE A CE2   1 
ATOM   3996  C  CZ    . PHE A 1 731  ? 141.299 160.961 108.105 1.00 38.49  ? 749  PHE A CZ    1 
ATOM   3997  N  N     . PHE A 1 732  ? 146.598 160.587 106.897 1.00 39.85  ? 750  PHE A N     1 
ATOM   3998  C  CA    . PHE A 1 732  ? 146.540 159.640 105.792 1.00 39.85  ? 750  PHE A CA    1 
ATOM   3999  C  C     . PHE A 1 732  ? 145.317 158.757 105.978 1.00 39.85  ? 750  PHE A C     1 
ATOM   4000  O  O     . PHE A 1 732  ? 145.176 158.102 107.016 1.00 39.85  ? 750  PHE A O     1 
ATOM   4001  C  CB    . PHE A 1 732  ? 147.801 158.780 105.728 1.00 39.85  ? 750  PHE A CB    1 
ATOM   4002  C  CG    . PHE A 1 732  ? 149.041 159.542 105.388 1.00 39.85  ? 750  PHE A CG    1 
ATOM   4003  C  CD1   . PHE A 1 732  ? 149.339 159.852 104.074 1.00 39.85  ? 750  PHE A CD1   1 
ATOM   4004  C  CD2   . PHE A 1 732  ? 149.917 159.935 106.380 1.00 39.85  ? 750  PHE A CD2   1 
ATOM   4005  C  CE1   . PHE A 1 732  ? 150.486 160.549 103.757 1.00 39.85  ? 750  PHE A CE1   1 
ATOM   4006  C  CE2   . PHE A 1 732  ? 151.066 160.630 106.070 1.00 39.85  ? 750  PHE A CE2   1 
ATOM   4007  C  CZ    . PHE A 1 732  ? 151.351 160.938 104.757 1.00 39.85  ? 750  PHE A CZ    1 
ATOM   4008  N  N     . LYS A 1 733  ? 144.443 158.734 104.980 1.00 37.24  ? 751  LYS A N     1 
ATOM   4009  C  CA    . LYS A 1 733  ? 143.264 157.888 105.058 1.00 37.24  ? 751  LYS A CA    1 
ATOM   4010  C  C     . LYS A 1 733  ? 143.659 156.418 105.087 1.00 37.24  ? 751  LYS A C     1 
ATOM   4011  O  O     . LYS A 1 733  ? 144.714 156.023 104.584 1.00 37.24  ? 751  LYS A O     1 
ATOM   4012  C  CB    . LYS A 1 733  ? 142.342 158.147 103.871 1.00 37.24  ? 751  LYS A CB    1 
ATOM   4013  C  CG    . LYS A 1 733  ? 141.427 159.338 104.033 1.00 37.24  ? 751  LYS A CG    1 
ATOM   4014  C  CD    . LYS A 1 733  ? 140.551 159.501 102.805 1.00 37.24  ? 751  LYS A CD    1 
ATOM   4015  C  CE    . LYS A 1 733  ? 139.921 158.180 102.404 1.00 37.24  ? 751  LYS A CE    1 
ATOM   4016  N  NZ    . LYS A 1 733  ? 139.021 157.640 103.458 1.00 37.24  ? 751  LYS A NZ    1 
ATOM   4017  N  N     . LEU A 1 734  ? 142.808 155.608 105.695 1.00 34.10  ? 752  LEU A N     1 
ATOM   4018  C  CA    . LEU A 1 734  ? 142.991 154.167 105.625 1.00 34.10  ? 752  LEU A CA    1 
ATOM   4019  C  C     . LEU A 1 734  ? 142.650 153.694 104.218 1.00 34.10  ? 752  LEU A C     1 
ATOM   4020  O  O     . LEU A 1 734  ? 141.603 154.075 103.682 1.00 34.10  ? 752  LEU A O     1 
ATOM   4021  C  CB    . LEU A 1 734  ? 142.110 153.455 106.647 1.00 34.10  ? 752  LEU A CB    1 
ATOM   4022  C  CG    . LEU A 1 734  ? 142.503 153.560 108.119 1.00 34.10  ? 752  LEU A CG    1 
ATOM   4023  C  CD1   . LEU A 1 734  ? 141.558 152.740 108.973 1.00 34.10  ? 752  LEU A CD1   1 
ATOM   4024  C  CD2   . LEU A 1 734  ? 143.931 153.104 108.321 1.00 34.10  ? 752  LEU A CD2   1 
ATOM   4025  N  N     . PRO A 1 735  ? 143.503 152.891 103.582 1.00 40.75  ? 753  PRO A N     1 
ATOM   4026  C  CA    . PRO A 1 735  ? 143.191 152.409 102.232 1.00 40.75  ? 753  PRO A CA    1 
ATOM   4027  C  C     . PRO A 1 735  ? 141.877 151.643 102.205 1.00 40.75  ? 753  PRO A C     1 
ATOM   4028  O  O     . PRO A 1 735  ? 141.598 150.815 103.074 1.00 40.75  ? 753  PRO A O     1 
ATOM   4029  C  CB    . PRO A 1 735  ? 144.380 151.503 101.898 1.00 40.75  ? 753  PRO A CB    1 
ATOM   4030  C  CG    . PRO A 1 735  ? 145.489 152.015 102.752 1.00 40.75  ? 753  PRO A CG    1 
ATOM   4031  C  CD    . PRO A 1 735  ? 144.839 152.459 104.027 1.00 40.75  ? 753  PRO A CD    1 
ATOM   4032  N  N     . HIS A 1 736  ? 141.071 151.926 101.187 1.00 62.09  ? 754  HIS A N     1 
ATOM   4033  C  CA    . HIS A 1 736  ? 139.763 151.312 101.018 1.00 62.09  ? 754  HIS A CA    1 
ATOM   4034  C  C     . HIS A 1 736  ? 139.751 150.494 99.734  1.00 62.09  ? 754  HIS A C     1 
ATOM   4035  O  O     . HIS A 1 736  ? 140.495 150.779 98.791  1.00 62.09  ? 754  HIS A O     1 
ATOM   4036  C  CB    . HIS A 1 736  ? 138.653 152.374 100.983 1.00 62.09  ? 754  HIS A CB    1 
ATOM   4037  C  CG    . HIS A 1 736  ? 137.272 151.814 101.131 1.00 62.09  ? 754  HIS A CG    1 
ATOM   4038  N  ND1   . HIS A 1 736  ? 136.551 151.319 100.066 1.00 62.09  ? 754  HIS A ND1   1 
ATOM   4039  C  CD2   . HIS A 1 736  ? 136.477 151.679 102.218 1.00 62.09  ? 754  HIS A CD2   1 
ATOM   4040  C  CE1   . HIS A 1 736  ? 135.373 150.898 100.491 1.00 62.09  ? 754  HIS A CE1   1 
ATOM   4041  N  NE2   . HIS A 1 736  ? 135.303 151.106 101.794 1.00 62.09  ? 754  HIS A NE2   1 
ATOM   4042  N  N     . LYS A 1 737  ? 138.900 149.467 99.707  1.00 72.46  ? 755  LYS A N     1 
ATOM   4043  C  CA    . LYS A 1 737  ? 138.839 148.585 98.547  1.00 72.46  ? 755  LYS A CA    1 
ATOM   4044  C  C     . LYS A 1 737  ? 138.302 149.287 97.306  1.00 72.46  ? 755  LYS A C     1 
ATOM   4045  O  O     . LYS A 1 737  ? 138.442 148.752 96.201  1.00 72.46  ? 755  LYS A O     1 
ATOM   4046  C  CB    . LYS A 1 737  ? 137.976 147.362 98.856  1.00 72.46  ? 755  LYS A CB    1 
ATOM   4047  C  CG    . LYS A 1 737  ? 136.501 147.675 99.028  1.00 72.46  ? 755  LYS A CG    1 
ATOM   4048  C  CD    . LYS A 1 737  ? 135.680 146.403 99.138  1.00 72.46  ? 755  LYS A CD    1 
ATOM   4049  C  CE    . LYS A 1 737  ? 134.193 146.708 99.179  1.00 72.46  ? 755  LYS A CE    1 
ATOM   4050  N  NZ    . LYS A 1 737  ? 133.375 145.465 99.221  1.00 72.46  ? 755  LYS A NZ    1 
ATOM   4051  N  N     . ASP A 1 738  ? 137.693 150.462 97.458  1.00 74.98  ? 756  ASP A N     1 
ATOM   4052  C  CA    . ASP A 1 738  ? 137.116 151.196 96.340  1.00 74.98  ? 756  ASP A CA    1 
ATOM   4053  C  C     . ASP A 1 738  ? 137.960 152.393 95.918  1.00 74.98  ? 756  ASP A C     1 
ATOM   4054  O  O     . ASP A 1 738  ? 137.491 153.220 95.130  1.00 74.98  ? 756  ASP A O     1 
ATOM   4055  C  CB    . ASP A 1 738  ? 135.696 151.648 96.682  1.00 74.98  ? 756  ASP A CB    1 
ATOM   4056  C  CG    . ASP A 1 738  ? 134.750 150.485 96.899  1.00 74.98  ? 756  ASP A CG    1 
ATOM   4057  O  OD1   . ASP A 1 738  ? 135.061 149.369 96.431  1.00 74.98  ? 756  ASP A OD1   1 
ATOM   4058  O  OD2   . ASP A 1 738  ? 133.693 150.686 97.533  1.00 74.98  ? 756  ASP A OD2   1 
ATOM   4059  N  N     . GLY A 1 739  ? 139.183 152.509 96.417  1.00 67.23  ? 757  GLY A N     1 
ATOM   4060  C  CA    . GLY A 1 739  ? 140.079 153.565 95.990  1.00 67.23  ? 757  GLY A CA    1 
ATOM   4061  C  C     . GLY A 1 739  ? 140.160 154.716 96.973  1.00 67.23  ? 757  GLY A C     1 
ATOM   4062  O  O     . GLY A 1 739  ? 139.676 154.661 98.107  1.00 67.23  ? 757  GLY A O     1 
ATOM   4063  N  N     . ASN A 1 740  ? 140.803 155.802 96.550  1.00 59.65  ? 758  ASN A N     1 
ATOM   4064  C  CA    . ASN A 1 740  ? 141.004 156.949 97.445  1.00 59.65  ? 758  ASN A CA    1 
ATOM   4065  C  C     . ASN A 1 740  ? 139.938 158.020 97.304  1.00 59.65  ? 758  ASN A C     1 
ATOM   4066  O  O     . ASN A 1 740  ? 140.101 159.128 97.810  1.00 59.65  ? 758  ASN A O     1 
ATOM   4067  C  CB    . ASN A 1 740  ? 142.375 157.572 97.190  1.00 59.65  ? 758  ASN A CB    1 
ATOM   4068  C  CG    . ASN A 1 740  ? 143.488 156.544 97.174  1.00 59.65  ? 758  ASN A CG    1 
ATOM   4069  O  OD1   . ASN A 1 740  ? 143.248 155.345 97.322  1.00 59.65  ? 758  ASN A OD1   1 
ATOM   4070  N  ND2   . ASN A 1 740  ? 144.718 157.009 96.990  1.00 59.65  ? 758  ASN A ND2   1 
ATOM   4071  N  N     . SER A 1 741  ? 138.860 157.710 96.603  1.00 61.60  ? 759  SER A N     1 
ATOM   4072  C  CA    . SER A 1 741  ? 137.752 158.647 96.480  1.00 61.60  ? 759  SER A CA    1 
ATOM   4073  C  C     . SER A 1 741  ? 136.608 158.353 97.441  1.00 61.60  ? 759  SER A C     1 
ATOM   4074  O  O     . SER A 1 741  ? 135.573 159.022 97.371  1.00 61.60  ? 759  SER A O     1 
ATOM   4075  C  CB    . SER A 1 741  ? 137.223 158.650 95.042  1.00 61.60  ? 759  SER A CB    1 
ATOM   4076  O  OG    . SER A 1 741  ? 136.089 159.491 94.920  1.00 61.60  ? 759  SER A OG    1 
ATOM   4077  N  N     . CYS A 1 742  ? 136.765 157.378 98.329  1.00 62.13  ? 760  CYS A N     1 
ATOM   4078  C  CA    . CYS A 1 742  ? 135.716 156.972 99.251  1.00 62.13  ? 760  CYS A CA    1 
ATOM   4079  C  C     . CYS A 1 742  ? 136.124 157.296 100.685 1.00 62.13  ? 760  CYS A C     1 
ATOM   4080  O  O     . CYS A 1 742  ? 137.205 157.829 100.947 1.00 62.13  ? 760  CYS A O     1 
ATOM   4081  C  CB    . CYS A 1 742  ? 135.406 155.483 99.085  1.00 62.13  ? 760  CYS A CB    1 
ATOM   4082  S  SG    . CYS A 1 742  ? 134.863 155.031 97.423  1.00 62.13  ? 760  CYS A SG    1 
ATOM   4083  N  N     . ASN A 1 743  ? 135.231 156.979 101.619 1.00 54.64  ? 761  ASN A N     1 
ATOM   4084  C  CA    . ASN A 1 743  ? 135.440 157.214 103.039 1.00 54.64  ? 761  ASN A CA    1 
ATOM   4085  C  C     . ASN A 1 743  ? 135.407 155.893 103.793 1.00 54.64  ? 761  ASN A C     1 
ATOM   4086  O  O     . ASN A 1 743  ? 134.730 154.945 103.387 1.00 54.64  ? 761  ASN A O     1 
ATOM   4087  C  CB    . ASN A 1 743  ? 134.374 158.155 103.611 1.00 54.64  ? 761  ASN A CB    1 
ATOM   4088  C  CG    . ASN A 1 743  ? 134.486 159.564 103.070 1.00 54.64  ? 761  ASN A CG    1 
ATOM   4089  O  OD1   . ASN A 1 743  ? 135.192 159.815 102.095 1.00 54.64  ? 761  ASN A OD1   1 
ATOM   4090  N  ND2   . ASN A 1 743  ? 133.788 160.497 103.707 1.00 54.64  ? 761  ASN A ND2   1 
ATOM   4091  N  N     . VAL A 1 744  ? 136.144 155.834 104.898 1.00 39.40  ? 762  VAL A N     1 
ATOM   4092  C  CA    . VAL A 1 744  ? 136.135 154.644 105.730 1.00 39.40  ? 762  VAL A CA    1 
ATOM   4093  C  C     . VAL A 1 744  ? 135.482 155.020 107.039 1.00 39.40  ? 762  VAL A C     1 
ATOM   4094  O  O     . VAL A 1 744  ? 135.829 156.030 107.639 1.00 39.40  ? 762  VAL A O     1 
ATOM   4095  C  CB    . VAL A 1 744  ? 137.544 154.098 105.980 1.00 39.40  ? 762  VAL A CB    1 
ATOM   4096  C  CG1   . VAL A 1 744  ? 137.465 152.662 106.470 1.00 39.40  ? 762  VAL A CG1   1 
ATOM   4097  C  CG2   . VAL A 1 744  ? 138.376 154.181 104.713 1.00 39.40  ? 762  VAL A CG2   1 
ATOM   4098  N  N     . GLY A 1 745  ? 134.540 154.218 107.488 1.00 34.81  ? 763  GLY A N     1 
ATOM   4099  C  CA    . GLY A 1 745  ? 133.795 154.500 108.696 1.00 34.81  ? 763  GLY A CA    1 
ATOM   4100  C  C     . GLY A 1 745  ? 134.004 153.481 109.795 1.00 34.81  ? 763  GLY A C     1 
ATOM   4101  O  O     . GLY A 1 745  ? 133.483 153.640 110.902 1.00 34.81  ? 763  GLY A O     1 
ATOM   4102  N  N     . SER A 1 746  ? 134.766 152.431 109.504 1.00 27.66  ? 764  SER A N     1 
ATOM   4103  C  CA    . SER A 1 746  ? 135.016 151.383 110.484 1.00 27.66  ? 764  SER A CA    1 
ATOM   4104  C  C     . SER A 1 746  ? 136.366 150.725 110.228 1.00 27.66  ? 764  SER A C     1 
ATOM   4105  O  O     . SER A 1 746  ? 136.510 149.960 109.264 1.00 27.66  ? 764  SER A O     1 
ATOM   4106  C  CB    . SER A 1 746  ? 133.901 150.337 110.450 1.00 27.66  ? 764  SER A CB    1 
ATOM   4107  O  OG    . SER A 1 746  ? 134.118 149.332 111.423 1.00 27.66  ? 764  SER A OG    1 
ATOM   4108  N  N     . PRO A 1 747  ? 137.377 150.990 111.060 1.00 21.80  ? 765  PRO A N     1 
ATOM   4109  C  CA    . PRO A 1 747  ? 138.680 150.345 110.861 1.00 21.80  ? 765  PRO A CA    1 
ATOM   4110  C  C     . PRO A 1 747  ? 138.691 148.905 111.343 1.00 21.80  ? 765  PRO A C     1 
ATOM   4111  O  O     . PRO A 1 747  ? 139.745 148.267 111.408 1.00 21.80  ? 765  PRO A O     1 
ATOM   4112  C  CB    . PRO A 1 747  ? 139.628 151.220 111.686 1.00 21.80  ? 765  PRO A CB    1 
ATOM   4113  C  CG    . PRO A 1 747  ? 138.777 151.751 112.764 1.00 21.80  ? 765  PRO A CG    1 
ATOM   4114  C  CD    . PRO A 1 747  ? 137.408 151.957 112.168 1.00 21.80  ? 765  PRO A CD    1 
ATOM   4115  N  N     . PHE A 1 748  ? 137.513 148.385 111.682 1.00 22.71  ? 766  PHE A N     1 
ATOM   4116  C  CA    . PHE A 1 748  ? 137.332 146.977 112.001 1.00 22.71  ? 766  PHE A CA    1 
ATOM   4117  C  C     . PHE A 1 748  ? 136.577 146.249 110.899 1.00 22.71  ? 766  PHE A C     1 
ATOM   4118  O  O     . PHE A 1 748  ? 135.951 145.215 111.151 1.00 22.71  ? 766  PHE A O     1 
ATOM   4119  C  CB    . PHE A 1 748  ? 136.611 146.826 113.338 1.00 22.71  ? 766  PHE A CB    1 
ATOM   4120  C  CG    . PHE A 1 748  ? 137.326 147.478 114.479 1.00 22.71  ? 766  PHE A CG    1 
ATOM   4121  C  CD1   . PHE A 1 748  ? 138.345 146.818 115.138 1.00 22.71  ? 766  PHE A CD1   1 
ATOM   4122  C  CD2   . PHE A 1 748  ? 136.989 148.756 114.884 1.00 22.71  ? 766  PHE A CD2   1 
ATOM   4123  C  CE1   . PHE A 1 748  ? 139.009 147.417 116.182 1.00 22.71  ? 766  PHE A CE1   1 
ATOM   4124  C  CE2   . PHE A 1 748  ? 137.650 149.361 115.927 1.00 22.71  ? 766  PHE A CE2   1 
ATOM   4125  C  CZ    . PHE A 1 748  ? 138.658 148.689 116.579 1.00 22.71  ? 766  PHE A CZ    1 
ATOM   4126  N  N     . ALA A 1 749  ? 136.627 146.777 109.679 1.00 39.77  ? 767  ALA A N     1 
ATOM   4127  C  CA    . ALA A 1 749  ? 135.920 146.204 108.550 1.00 39.77  ? 767  ALA A CA    1 
ATOM   4128  C  C     . ALA A 1 749  ? 136.670 144.990 108.008 1.00 39.77  ? 767  ALA A C     1 
ATOM   4129  O  O     . ALA A 1 749  ? 137.838 144.748 108.323 1.00 39.77  ? 767  ALA A O     1 
ATOM   4130  C  CB    . ALA A 1 749  ? 135.732 147.248 107.451 1.00 39.77  ? 767  ALA A CB    1 
ATOM   4131  N  N     . LYS A 1 750  ? 135.968 144.218 107.175 1.00 50.34  ? 768  LYS A N     1 
ATOM   4132  C  CA    . LYS A 1 750  ? 136.539 142.996 106.621 1.00 50.34  ? 768  LYS A CA    1 
ATOM   4133  C  C     . LYS A 1 750  ? 137.816 143.267 105.836 1.00 50.34  ? 768  LYS A C     1 
ATOM   4134  O  O     . LYS A 1 750  ? 138.718 142.423 105.810 1.00 50.34  ? 768  LYS A O     1 
ATOM   4135  C  CB    . LYS A 1 750  ? 135.503 142.305 105.737 1.00 50.34  ? 768  LYS A CB    1 
ATOM   4136  C  CG    . LYS A 1 750  ? 134.211 141.980 106.467 1.00 50.34  ? 768  LYS A CG    1 
ATOM   4137  C  CD    . LYS A 1 750  ? 133.040 141.846 105.510 1.00 50.34  ? 768  LYS A CD    1 
ATOM   4138  C  CE    . LYS A 1 750  ? 133.293 140.773 104.469 1.00 50.34  ? 768  LYS A CE    1 
ATOM   4139  N  NZ    . LYS A 1 750  ? 132.164 140.674 103.505 1.00 50.34  ? 768  LYS A NZ    1 
ATOM   4140  N  N     . ASP A 1 751  ? 137.913 144.432 105.193 1.00 44.15  ? 769  ASP A N     1 
ATOM   4141  C  CA    . ASP A 1 751  ? 139.086 144.745 104.385 1.00 44.15  ? 769  ASP A CA    1 
ATOM   4142  C  C     . ASP A 1 751  ? 140.350 144.912 105.219 1.00 44.15  ? 769  ASP A C     1 
ATOM   4143  O  O     . ASP A 1 751  ? 141.453 144.737 104.690 1.00 44.15  ? 769  ASP A O     1 
ATOM   4144  C  CB    . ASP A 1 751  ? 138.828 146.012 103.566 1.00 44.15  ? 769  ASP A CB    1 
ATOM   4145  C  CG    . ASP A 1 751  ? 140.027 146.424 102.734 1.00 44.15  ? 769  ASP A CG    1 
ATOM   4146  O  OD1   . ASP A 1 751  ? 140.396 145.674 101.806 1.00 44.15  ? 769  ASP A OD1   1 
ATOM   4147  O  OD2   . ASP A 1 751  ? 140.600 147.500 103.007 1.00 44.15  ? 769  ASP A OD2   1 
ATOM   4148  N  N     . PHE A 1 752  ? 140.221 145.237 106.502 1.00 33.10  ? 770  PHE A N     1 
ATOM   4149  C  CA    . PHE A 1 752  ? 141.372 145.533 107.345 1.00 33.10  ? 770  PHE A CA    1 
ATOM   4150  C  C     . PHE A 1 752  ? 141.845 144.344 108.165 1.00 33.10  ? 770  PHE A C     1 
ATOM   4151  O  O     . PHE A 1 752  ? 142.842 144.468 108.882 1.00 33.10  ? 770  PHE A O     1 
ATOM   4152  C  CB    . PHE A 1 752  ? 141.051 146.700 108.276 1.00 33.10  ? 770  PHE A CB    1 
ATOM   4153  C  CG    . PHE A 1 752  ? 140.791 147.979 107.556 1.00 33.10  ? 770  PHE A CG    1 
ATOM   4154  C  CD1   . PHE A 1 752  ? 141.836 148.804 107.197 1.00 33.10  ? 770  PHE A CD1   1 
ATOM   4155  C  CD2   . PHE A 1 752  ? 139.502 148.350 107.225 1.00 33.10  ? 770  PHE A CD2   1 
ATOM   4156  C  CE1   . PHE A 1 752  ? 141.605 149.978 106.531 1.00 33.10  ? 770  PHE A CE1   1 
ATOM   4157  C  CE2   . PHE A 1 752  ? 139.263 149.526 106.557 1.00 33.10  ? 770  PHE A CE2   1 
ATOM   4158  C  CZ    . PHE A 1 752  ? 140.318 150.342 106.209 1.00 33.10  ? 770  PHE A CZ    1 
ATOM   4159  N  N     . LEU A 1 753  ? 141.155 143.209 108.090 1.00 29.68  ? 771  LEU A N     1 
ATOM   4160  C  CA    . LEU A 1 753  ? 141.562 142.045 108.874 1.00 29.68  ? 771  LEU A CA    1 
ATOM   4161  C  C     . LEU A 1 753  ? 143.000 141.615 108.605 1.00 29.68  ? 771  LEU A C     1 
ATOM   4162  O  O     . LEU A 1 753  ? 143.729 141.351 109.577 1.00 29.68  ? 771  LEU A O     1 
ATOM   4163  C  CB    . LEU A 1 753  ? 140.580 140.895 108.633 1.00 29.68  ? 771  LEU A CB    1 
ATOM   4164  C  CG    . LEU A 1 753  ? 140.632 139.766 109.659 1.00 29.68  ? 771  LEU A CG    1 
ATOM   4165  C  CD1   . LEU A 1 753  ? 140.123 140.262 110.999 1.00 29.68  ? 771  LEU A CD1   1 
ATOM   4166  C  CD2   . LEU A 1 753  ? 139.826 138.573 109.183 1.00 29.68  ? 771  LEU A CD2   1 
ATOM   4167  N  N     . PRO A 1 754  ? 143.476 141.516 107.355 1.00 30.76  ? 772  PRO A N     1 
ATOM   4168  C  CA    . PRO A 1 754  ? 144.873 141.097 107.151 1.00 30.76  ? 772  PRO A CA    1 
ATOM   4169  C  C     . PRO A 1 754  ? 145.893 142.025 107.785 1.00 30.76  ? 772  PRO A C     1 
ATOM   4170  O  O     . PRO A 1 754  ? 146.946 141.555 108.231 1.00 30.76  ? 772  PRO A O     1 
ATOM   4171  C  CB    . PRO A 1 754  ? 145.010 141.075 105.623 1.00 30.76  ? 772  PRO A CB    1 
ATOM   4172  C  CG    . PRO A 1 754  ? 143.635 140.862 105.131 1.00 30.76  ? 772  PRO A CG    1 
ATOM   4173  C  CD    . PRO A 1 754  ? 142.760 141.623 106.071 1.00 30.76  ? 772  PRO A CD    1 
ATOM   4174  N  N     . LYS A 1 755  ? 145.617 143.323 107.840 1.00 27.88  ? 773  LYS A N     1 
ATOM   4175  C  CA    . LYS A 1 755  ? 146.585 144.280 108.365 1.00 27.88  ? 773  LYS A CA    1 
ATOM   4176  C  C     . LYS A 1 755  ? 146.525 144.345 109.886 1.00 27.88  ? 773  LYS A C     1 
ATOM   4177  O  O     . LYS A 1 755  ? 147.484 144.762 110.534 1.00 27.88  ? 773  LYS A O     1 
ATOM   4178  C  CB    . LYS A 1 755  ? 146.351 145.670 107.772 1.00 27.88  ? 773  LYS A CB    1 
ATOM   4179  C  CG    . LYS A 1 755  ? 146.305 145.708 106.253 1.00 27.88  ? 773  LYS A CG    1 
ATOM   4180  C  CD    . LYS A 1 755  ? 144.874 145.641 105.744 1.00 27.88  ? 773  LYS A CD    1 
ATOM   4181  C  CE    . LYS A 1 755  ? 144.816 145.723 104.229 1.00 27.88  ? 773  LYS A CE    1 
ATOM   4182  N  NZ    . LYS A 1 755  ? 143.413 145.727 103.732 1.00 27.88  ? 773  LYS A NZ    1 
ATOM   4183  N  N     . LEU A 1 761  ? 147.710 147.359 111.874 1.00 25.81  ? 779  LEU A N     1 
ATOM   4184  C  CA    . LEU A 1 761  ? 146.516 147.538 112.691 1.00 25.81  ? 779  LEU A CA    1 
ATOM   4185  C  C     . LEU A 1 761  ? 146.631 146.752 113.990 1.00 25.81  ? 779  LEU A C     1 
ATOM   4186  O  O     . LEU A 1 761  ? 146.222 145.594 114.062 1.00 25.81  ? 779  LEU A O     1 
ATOM   4187  C  CB    . LEU A 1 761  ? 145.268 147.101 111.926 1.00 25.81  ? 779  LEU A CB    1 
ATOM   4188  C  CG    . LEU A 1 761  ? 143.938 147.608 112.480 1.00 25.81  ? 779  LEU A CG    1 
ATOM   4189  C  CD1   . LEU A 1 761  ? 143.781 149.083 112.163 1.00 25.81  ? 779  LEU A CD1   1 
ATOM   4190  C  CD2   . LEU A 1 761  ? 142.767 146.807 111.933 1.00 25.81  ? 779  LEU A CD2   1 
ATOM   4191  N  N     . GLN A 1 762  ? 147.187 147.387 115.019 1.00 24.95  ? 780  GLN A N     1 
ATOM   4192  C  CA    . GLN A 1 762  ? 147.402 146.737 116.301 1.00 24.95  ? 780  GLN A CA    1 
ATOM   4193  C  C     . GLN A 1 762  ? 147.192 147.738 117.425 1.00 24.95  ? 780  GLN A C     1 
ATOM   4194  O  O     . GLN A 1 762  ? 147.394 148.942 117.249 1.00 24.95  ? 780  GLN A O     1 
ATOM   4195  C  CB    . GLN A 1 762  ? 148.809 146.138 116.389 1.00 24.95  ? 780  GLN A CB    1 
ATOM   4196  C  CG    . GLN A 1 762  ? 149.907 147.112 116.001 1.00 24.95  ? 780  GLN A CG    1 
ATOM   4197  C  CD    . GLN A 1 762  ? 151.282 146.480 116.019 1.00 24.95  ? 780  GLN A CD    1 
ATOM   4198  O  OE1   . GLN A 1 762  ? 151.466 145.381 116.543 1.00 24.95  ? 780  GLN A OE1   1 
ATOM   4199  N  NE2   . GLN A 1 762  ? 152.258 147.170 115.441 1.00 24.95  ? 780  GLN A NE2   1 
ATOM   4200  N  N     . ALA A 1 763  ? 146.781 147.227 118.584 1.00 22.07  ? 781  ALA A N     1 
ATOM   4201  C  CA    . ALA A 1 763  ? 146.662 148.067 119.766 1.00 22.07  ? 781  ALA A CA    1 
ATOM   4202  C  C     . ALA A 1 763  ? 148.034 148.590 120.174 1.00 22.07  ? 781  ALA A C     1 
ATOM   4203  O  O     . ALA A 1 763  ? 149.060 147.942 119.958 1.00 22.07  ? 781  ALA A O     1 
ATOM   4204  C  CB    . ALA A 1 763  ? 146.024 147.289 120.914 1.00 22.07  ? 781  ALA A CB    1 
ATOM   4205  N  N     . GLY A 1 764  ? 148.047 149.775 120.777 1.00 27.33  ? 782  GLY A N     1 
ATOM   4206  C  CA    . GLY A 1 764  ? 149.276 150.506 120.978 1.00 27.33  ? 782  GLY A CA    1 
ATOM   4207  C  C     . GLY A 1 764  ? 149.900 150.334 122.347 1.00 27.33  ? 782  GLY A C     1 
ATOM   4208  O  O     . GLY A 1 764  ? 150.508 149.304 122.657 1.00 27.33  ? 782  GLY A O     1 
ATOM   4209  N  N     . PRO A 1 765  ? 149.768 151.357 123.195 1.00 37.44  ? 783  PRO A N     1 
ATOM   4210  C  CA    . PRO A 1 765  ? 150.484 151.361 124.478 1.00 37.44  ? 783  PRO A CA    1 
ATOM   4211  C  C     . PRO A 1 765  ? 149.987 150.312 125.458 1.00 37.44  ? 783  PRO A C     1 
ATOM   4212  O  O     . PRO A 1 765  ? 149.129 149.488 125.125 1.00 37.44  ? 783  PRO A O     1 
ATOM   4213  C  CB    . PRO A 1 765  ? 150.238 152.780 125.008 1.00 37.44  ? 783  PRO A CB    1 
ATOM   4214  C  CG    . PRO A 1 765  ? 148.968 153.203 124.359 1.00 37.44  ? 783  PRO A CG    1 
ATOM   4215  C  CD    . PRO A 1 765  ? 148.999 152.594 122.988 1.00 37.44  ? 783  PRO A CD    1 
ATOM   4216  N  N     . GLY A 1 766  ? 150.532 150.347 126.673 1.00 44.57  ? 784  GLY A N     1 
ATOM   4217  C  CA    . GLY A 1 766  ? 150.308 149.325 127.677 1.00 44.57  ? 784  GLY A CA    1 
ATOM   4218  C  C     . GLY A 1 766  ? 148.861 149.006 127.991 1.00 44.57  ? 784  GLY A C     1 
ATOM   4219  O  O     . GLY A 1 766  ? 147.948 149.754 127.626 1.00 44.57  ? 784  GLY A O     1 
ATOM   4220  N  N     . GLY A 1 767  ? 148.648 147.891 128.681 1.00 30.74  ? 785  GLY A N     1 
ATOM   4221  C  CA    . GLY A 1 767  ? 147.316 147.385 128.928 1.00 30.74  ? 785  GLY A CA    1 
ATOM   4222  C  C     . GLY A 1 767  ? 147.059 146.140 128.109 1.00 30.74  ? 785  GLY A C     1 
ATOM   4223  O  O     . GLY A 1 767  ? 147.116 146.179 126.878 1.00 30.74  ? 785  GLY A O     1 
ATOM   4224  N  N     . ALA A 1 768  ? 146.784 145.026 128.781 1.00 24.60  ? 786  ALA A N     1 
ATOM   4225  C  CA    . ALA A 1 768  ? 146.576 143.748 128.118 1.00 24.60  ? 786  ALA A CA    1 
ATOM   4226  C  C     . ALA A 1 768  ? 145.119 143.508 127.756 1.00 24.60  ? 786  ALA A C     1 
ATOM   4227  O  O     . ALA A 1 768  ? 144.726 142.357 127.537 1.00 24.60  ? 786  ALA A O     1 
ATOM   4228  C  CB    . ALA A 1 768  ? 147.091 142.607 128.997 1.00 24.60  ? 786  ALA A CB    1 
ATOM   4229  N  N     . SER A 1 769  ? 144.308 144.562 127.697 1.00 18.85  ? 787  SER A N     1 
ATOM   4230  C  CA    . SER A 1 769  ? 142.906 144.430 127.330 1.00 18.85  ? 787  SER A CA    1 
ATOM   4231  C  C     . SER A 1 769  ? 142.605 144.946 125.932 1.00 18.85  ? 787  SER A C     1 
ATOM   4232  O  O     . SER A 1 769  ? 141.633 144.500 125.316 1.00 18.85  ? 787  SER A O     1 
ATOM   4233  C  CB    . SER A 1 769  ? 142.025 145.163 128.346 1.00 18.85  ? 787  SER A CB    1 
ATOM   4234  O  OG    . SER A 1 769  ? 142.488 146.483 128.565 1.00 18.85  ? 787  SER A OG    1 
ATOM   4235  N  N     . GLY A 1 770  ? 143.413 145.868 125.418 1.00 17.93  ? 788  GLY A N     1 
ATOM   4236  C  CA    . GLY A 1 770  ? 143.293 146.323 124.054 1.00 17.93  ? 788  GLY A CA    1 
ATOM   4237  C  C     . GLY A 1 770  ? 143.716 145.262 123.058 1.00 17.93  ? 788  GLY A C     1 
ATOM   4238  O  O     . GLY A 1 770  ? 142.938 144.844 122.190 1.00 17.93  ? 788  GLY A O     1 
ATOM   4239  N  N     . PRO A 1 771  ? 144.973 144.812 123.155 1.00 14.87  ? 789  PRO A N     1 
ATOM   4240  C  CA    . PRO A 1 771  ? 145.412 143.709 122.287 1.00 14.87  ? 789  PRO A CA    1 
ATOM   4241  C  C     . PRO A 1 771  ? 144.543 142.479 122.417 1.00 14.87  ? 789  PRO A C     1 
ATOM   4242  O  O     . PRO A 1 771  ? 144.287 141.800 121.418 1.00 14.87  ? 789  PRO A O     1 
ATOM   4243  C  CB    . PRO A 1 771  ? 146.846 143.447 122.761 1.00 14.87  ? 789  PRO A CB    1 
ATOM   4244  C  CG    . PRO A 1 771  ? 147.298 144.750 123.304 1.00 14.87  ? 789  PRO A CG    1 
ATOM   4245  C  CD    . PRO A 1 771  ? 146.089 145.373 123.936 1.00 14.87  ? 789  PRO A CD    1 
ATOM   4246  N  N     . ARG A 1 772  ? 144.069 142.176 123.626 1.00 14.03  ? 790  ARG A N     1 
ATOM   4247  C  CA    . ARG A 1 772  ? 143.154 141.053 123.788 1.00 14.03  ? 790  ARG A CA    1 
ATOM   4248  C  C     . ARG A 1 772  ? 141.853 141.294 123.037 1.00 14.03  ? 790  ARG A C     1 
ATOM   4249  O  O     . ARG A 1 772  ? 141.297 140.370 122.438 1.00 14.03  ? 790  ARG A O     1 
ATOM   4250  C  CB    . ARG A 1 772  ? 142.885 140.802 125.270 1.00 14.03  ? 790  ARG A CB    1 
ATOM   4251  C  CG    . ARG A 1 772  ? 141.991 139.608 125.535 1.00 14.03  ? 790  ARG A CG    1 
ATOM   4252  C  CD    . ARG A 1 772  ? 142.495 138.387 124.794 1.00 14.03  ? 790  ARG A CD    1 
ATOM   4253  N  NE    . ARG A 1 772  ? 141.577 137.260 124.898 1.00 14.03  ? 790  ARG A NE    1 
ATOM   4254  C  CZ    . ARG A 1 772  ? 141.704 136.130 124.217 1.00 14.03  ? 790  ARG A CZ    1 
ATOM   4255  N  NH1   . ARG A 1 772  ? 142.700 135.945 123.368 1.00 14.03  ? 790  ARG A NH1   1 
ATOM   4256  N  NH2   . ARG A 1 772  ? 140.807 135.165 124.390 1.00 14.03  ? 790  ARG A NH2   1 
ATOM   4257  N  N     . ALA A 1 773  ? 141.354 142.532 123.047 1.00 16.51  ? 791  ALA A N     1 
ATOM   4258  C  CA    . ALA A 1 773  ? 140.141 142.840 122.295 1.00 16.51  ? 791  ALA A CA    1 
ATOM   4259  C  C     . ALA A 1 773  ? 140.362 142.665 120.798 1.00 16.51  ? 791  ALA A C     1 
ATOM   4260  O  O     . ALA A 1 773  ? 139.494 142.141 120.091 1.00 16.51  ? 791  ALA A O     1 
ATOM   4261  C  CB    . ALA A 1 773  ? 139.673 144.258 122.611 1.00 16.51  ? 791  ALA A CB    1 
ATOM   4262  N  N     . LEU A 1 774  ? 141.522 143.094 120.296 1.00 22.16  ? 792  LEU A N     1 
ATOM   4263  C  CA    . LEU A 1 774  ? 141.823 142.892 118.881 1.00 22.16  ? 792  LEU A CA    1 
ATOM   4264  C  C     . LEU A 1 774  ? 141.930 141.410 118.541 1.00 22.16  ? 792  LEU A C     1 
ATOM   4265  O  O     . LEU A 1 774  ? 141.480 140.974 117.474 1.00 22.16  ? 792  LEU A O     1 
ATOM   4266  C  CB    . LEU A 1 774  ? 143.110 143.621 118.503 1.00 22.16  ? 792  LEU A CB    1 
ATOM   4267  C  CG    . LEU A 1 774  ? 142.907 144.830 117.597 1.00 22.16  ? 792  LEU A CG    1 
ATOM   4268  C  CD1   . LEU A 1 774  ? 144.229 145.290 117.036 1.00 22.16  ? 792  LEU A CD1   1 
ATOM   4269  C  CD2   . LEU A 1 774  ? 141.945 144.482 116.481 1.00 22.16  ? 792  LEU A CD2   1 
ATOM   4270  N  N     . GLU A 1 775  ? 142.539 140.620 119.428 1.00 19.63  ? 793  GLU A N     1 
ATOM   4271  C  CA    . GLU A 1 775  ? 142.617 139.184 119.190 1.00 19.63  ? 793  GLU A CA    1 
ATOM   4272  C  C     . GLU A 1 775  ? 141.231 138.556 119.194 1.00 19.63  ? 793  GLU A C     1 
ATOM   4273  O  O     . GLU A 1 775  ? 140.952 137.658 118.396 1.00 19.63  ? 793  GLU A O     1 
ATOM   4274  C  CB    . GLU A 1 775  ? 143.514 138.512 120.227 1.00 19.63  ? 793  GLU A CB    1 
ATOM   4275  C  CG    . GLU A 1 775  ? 144.934 139.046 120.270 1.00 19.63  ? 793  GLU A CG    1 
ATOM   4276  C  CD    . GLU A 1 775  ? 145.581 139.112 118.904 1.00 19.63  ? 793  GLU A CD    1 
ATOM   4277  O  OE1   . GLU A 1 775  ? 145.458 138.136 118.134 1.00 19.63  ? 793  GLU A OE1   1 
ATOM   4278  O  OE2   . GLU A 1 775  ? 146.213 140.145 118.598 1.00 19.63  ? 793  GLU A OE2   1 
ATOM   4279  N  N     . ILE A 1 776  ? 140.350 139.014 120.084 1.00 38.40  ? 794  ILE A N     1 
ATOM   4280  C  CA    . ILE A 1 776  ? 138.972 138.534 120.079 1.00 38.40  ? 794  ILE A CA    1 
ATOM   4281  C  C     . ILE A 1 776  ? 138.303 138.869 118.755 1.00 38.40  ? 794  ILE A C     1 
ATOM   4282  O  O     . ILE A 1 776  ? 137.593 138.042 118.169 1.00 38.40  ? 794  ILE A O     1 
ATOM   4283  C  CB    . ILE A 1 776  ? 138.183 139.130 121.260 1.00 38.40  ? 794  ILE A CB    1 
ATOM   4284  C  CG1   . ILE A 1 776  ? 138.780 138.708 122.601 1.00 38.40  ? 794  ILE A CG1   1 
ATOM   4285  C  CG2   . ILE A 1 776  ? 136.738 138.711 121.174 1.00 38.40  ? 794  ILE A CG2   1 
ATOM   4286  C  CD1   . ILE A 1 776  ? 138.747 137.234 122.845 1.00 38.40  ? 794  ILE A CD1   1 
ATOM   4287  N  N     . ASN A 1 777  ? 138.519 140.091 118.267 1.00 23.81  ? 795  ASN A N     1 
ATOM   4288  C  CA    . ASN A 1 777  ? 137.926 140.508 117.000 1.00 23.81  ? 795  ASN A CA    1 
ATOM   4289  C  C     . ASN A 1 777  ? 138.398 139.623 115.855 1.00 23.81  ? 795  ASN A C     1 
ATOM   4290  O  O     . ASN A 1 777  ? 137.597 139.182 115.025 1.00 23.81  ? 795  ASN A O     1 
ATOM   4291  C  CB    . ASN A 1 777  ? 138.271 141.969 116.719 1.00 23.81  ? 795  ASN A CB    1 
ATOM   4292  C  CG    . ASN A 1 777  ? 137.771 142.432 115.372 1.00 23.81  ? 795  ASN A CG    1 
ATOM   4293  O  OD1   . ASN A 1 777  ? 136.693 142.040 114.929 1.00 23.81  ? 795  ASN A OD1   1 
ATOM   4294  N  ND2   . ASN A 1 777  ? 138.558 143.265 114.706 1.00 23.81  ? 795  ASN A ND2   1 
ATOM   4295  N  N     . LYS A 1 778  ? 139.706 139.367 115.784 1.00 17.71  ? 796  LYS A N     1 
ATOM   4296  C  CA    . LYS A 1 778  ? 140.230 138.522 114.716 1.00 17.71  ? 796  LYS A CA    1 
ATOM   4297  C  C     . LYS A 1 778  ? 139.739 137.087 114.850 1.00 17.71  ? 796  LYS A C     1 
ATOM   4298  O  O     . LYS A 1 778  ? 139.449 136.432 113.844 1.00 17.71  ? 796  LYS A O     1 
ATOM   4299  C  CB    . LYS A 1 778  ? 141.754 138.573 114.694 1.00 17.71  ? 796  LYS A CB    1 
ATOM   4300  C  CG    . LYS A 1 778  ? 142.299 139.863 114.124 1.00 17.71  ? 796  LYS A CG    1 
ATOM   4301  C  CD    . LYS A 1 778  ? 143.803 139.811 113.960 1.00 17.71  ? 796  LYS A CD    1 
ATOM   4302  C  CE    . LYS A 1 778  ? 144.501 139.768 115.304 1.00 17.71  ? 796  LYS A CE    1 
ATOM   4303  N  NZ    . LYS A 1 778  ? 145.977 139.869 115.148 1.00 17.71  ? 796  LYS A NZ    1 
ATOM   4304  N  N     . MET A 1 779  ? 139.650 136.576 116.079 1.00 19.82  ? 797  MET A N     1 
ATOM   4305  C  CA    . MET A 1 779  ? 139.127 135.230 116.283 1.00 19.82  ? 797  MET A CA    1 
ATOM   4306  C  C     . MET A 1 779  ? 137.688 135.120 115.810 1.00 19.82  ? 797  MET A C     1 
ATOM   4307  O  O     . MET A 1 779  ? 137.289 134.095 115.248 1.00 19.82  ? 797  MET A O     1 
ATOM   4308  C  CB    . MET A 1 779  ? 139.214 134.837 117.757 1.00 19.82  ? 797  MET A CB    1 
ATOM   4309  C  CG    . MET A 1 779  ? 140.605 134.542 118.268 1.00 19.82  ? 797  MET A CG    1 
ATOM   4310  S  SD    . MET A 1 779  ? 140.575 133.998 119.985 1.00 19.82  ? 797  MET A SD    1 
ATOM   4311  C  CE    . MET A 1 779  ? 142.327 133.887 120.328 1.00 19.82  ? 797  MET A CE    1 
ATOM   4312  N  N     . ILE A 1 780  ? 136.885 136.156 116.045 1.00 18.00  ? 798  ILE A N     1 
ATOM   4313  C  CA    . ILE A 1 780  ? 135.466 136.056 115.732 1.00 18.00  ? 798  ILE A CA    1 
ATOM   4314  C  C     . ILE A 1 780  ? 135.130 136.440 114.296 1.00 18.00  ? 798  ILE A C     1 
ATOM   4315  O  O     . ILE A 1 780  ? 134.110 135.973 113.780 1.00 18.00  ? 798  ILE A O     1 
ATOM   4316  C  CB    . ILE A 1 780  ? 134.613 136.900 116.697 1.00 18.00  ? 798  ILE A CB    1 
ATOM   4317  C  CG1   . ILE A 1 780  ? 134.937 138.386 116.566 1.00 18.00  ? 798  ILE A CG1   1 
ATOM   4318  C  CG2   . ILE A 1 780  ? 134.805 136.442 118.128 1.00 18.00  ? 798  ILE A CG2   1 
ATOM   4319  C  CD1   . ILE A 1 780  ? 134.193 139.244 117.560 1.00 18.00  ? 798  ILE A CD1   1 
ATOM   4320  N  N     . SER A 1 781  ? 135.973 137.237 113.631 1.00 18.75  ? 799  SER A N     1 
ATOM   4321  C  CA    . SER A 1 781  ? 135.689 137.805 112.313 1.00 18.75  ? 799  SER A CA    1 
ATOM   4322  C  C     . SER A 1 781  ? 135.012 136.844 111.343 1.00 18.75  ? 799  SER A C     1 
ATOM   4323  O  O     . SER A 1 781  ? 133.985 137.183 110.744 1.00 18.75  ? 799  SER A O     1 
ATOM   4324  C  CB    . SER A 1 781  ? 136.983 138.321 111.685 1.00 18.75  ? 799  SER A CB    1 
ATOM   4325  O  OG    . SER A 1 781  ? 137.909 137.266 111.502 1.00 18.75  ? 799  SER A OG    1 
ATOM   4326  N  N     . PHE A 1 782  ? 135.588 135.653 111.173 1.00 17.97  ? 800  PHE A N     1 
ATOM   4327  C  CA    . PHE A 1 782  ? 135.030 134.666 110.255 1.00 17.97  ? 800  PHE A CA    1 
ATOM   4328  C  C     . PHE A 1 782  ? 133.585 134.330 110.607 1.00 17.97  ? 800  PHE A C     1 
ATOM   4329  O  O     . PHE A 1 782  ? 132.691 134.390 109.757 1.00 17.97  ? 800  PHE A O     1 
ATOM   4330  C  CB    . PHE A 1 782  ? 135.898 133.406 110.269 1.00 17.97  ? 800  PHE A CB    1 
ATOM   4331  C  CG    . PHE A 1 782  ? 135.246 132.206 109.645 1.00 17.97  ? 800  PHE A CG    1 
ATOM   4332  C  CD1   . PHE A 1 782  ? 134.589 131.272 110.426 1.00 17.97  ? 800  PHE A CD1   1 
ATOM   4333  C  CD2   . PHE A 1 782  ? 135.299 132.006 108.279 1.00 17.97  ? 800  PHE A CD2   1 
ATOM   4334  C  CE1   . PHE A 1 782  ? 133.991 130.170 109.855 1.00 17.97  ? 800  PHE A CE1   1 
ATOM   4335  C  CE2   . PHE A 1 782  ? 134.704 130.903 107.705 1.00 17.97  ? 800  PHE A CE2   1 
ATOM   4336  C  CZ    . PHE A 1 782  ? 134.050 129.985 108.495 1.00 17.97  ? 800  PHE A CZ    1 
ATOM   4337  N  N     . TRP A 1 783  ? 133.340 133.974 111.868 1.00 17.72  ? 801  TRP A N     1 
ATOM   4338  C  CA    . TRP A 1 783  ? 132.004 133.552 112.273 1.00 17.72  ? 801  TRP A CA    1 
ATOM   4339  C  C     . TRP A 1 783  ? 131.040 134.729 112.289 1.00 17.72  ? 801  TRP A C     1 
ATOM   4340  O  O     . TRP A 1 783  ? 129.843 134.571 112.040 1.00 17.72  ? 801  TRP A O     1 
ATOM   4341  C  CB    . TRP A 1 783  ? 132.071 132.886 113.641 1.00 17.72  ? 801  TRP A CB    1 
ATOM   4342  C  CG    . TRP A 1 783  ? 130.800 132.273 114.070 1.00 17.72  ? 801  TRP A CG    1 
ATOM   4343  C  CD1   . TRP A 1 783  ? 129.852 132.834 114.862 1.00 17.72  ? 801  TRP A CD1   1 
ATOM   4344  C  CD2   . TRP A 1 783  ? 130.329 130.966 113.742 1.00 17.72  ? 801  TRP A CD2   1 
ATOM   4345  N  NE1   . TRP A 1 783  ? 128.813 131.958 115.051 1.00 17.72  ? 801  TRP A NE1   1 
ATOM   4346  C  CE2   . TRP A 1 783  ? 129.083 130.801 114.371 1.00 17.72  ? 801  TRP A CE2   1 
ATOM   4347  C  CE3   . TRP A 1 783  ? 130.841 129.918 112.976 1.00 17.72  ? 801  TRP A CE3   1 
ATOM   4348  C  CZ2   . TRP A 1 783  ? 128.339 129.629 114.258 1.00 17.72  ? 801  TRP A CZ2   1 
ATOM   4349  C  CZ3   . TRP A 1 783  ? 130.103 128.758 112.865 1.00 17.72  ? 801  TRP A CZ3   1 
ATOM   4350  C  CH2   . TRP A 1 783  ? 128.866 128.622 113.502 1.00 17.72  ? 801  TRP A CH2   1 
ATOM   4351  N  N     . ARG A 1 784  ? 131.550 135.920 112.585 1.00 19.64  ? 802  ARG A N     1 
ATOM   4352  C  CA    . ARG A 1 784  ? 130.731 137.124 112.529 1.00 19.64  ? 802  ARG A CA    1 
ATOM   4353  C  C     . ARG A 1 784  ? 130.221 137.366 111.116 1.00 19.64  ? 802  ARG A C     1 
ATOM   4354  O  O     . ARG A 1 784  ? 129.022 137.577 110.900 1.00 19.64  ? 802  ARG A O     1 
ATOM   4355  C  CB    . ARG A 1 784  ? 131.542 138.322 113.018 1.00 19.64  ? 802  ARG A CB    1 
ATOM   4356  C  CG    . ARG A 1 784  ? 130.905 139.662 112.721 1.00 19.64  ? 802  ARG A CG    1 
ATOM   4357  C  CD    . ARG A 1 784  ? 131.953 140.756 112.663 1.00 19.64  ? 802  ARG A CD    1 
ATOM   4358  N  NE    . ARG A 1 784  ? 132.665 140.903 113.926 1.00 19.64  ? 802  ARG A NE    1 
ATOM   4359  C  CZ    . ARG A 1 784  ? 133.764 141.626 114.083 1.00 19.64  ? 802  ARG A CZ    1 
ATOM   4360  N  NH1   . ARG A 1 784  ? 134.319 142.270 113.070 1.00 19.64  ? 802  ARG A NH1   1 
ATOM   4361  N  NH2   . ARG A 1 784  ? 134.324 141.704 115.287 1.00 19.64  ? 802  ARG A NH2   1 
ATOM   4362  N  N     . ASN A 1 785  ? 131.125 137.327 110.137 1.00 25.07  ? 803  ASN A N     1 
ATOM   4363  C  CA    . ASN A 1 785  ? 130.761 137.619 108.756 1.00 25.07  ? 803  ASN A CA    1 
ATOM   4364  C  C     . ASN A 1 785  ? 130.068 136.458 108.057 1.00 25.07  ? 803  ASN A C     1 
ATOM   4365  O  O     . ASN A 1 785  ? 129.430 136.674 107.023 1.00 25.07  ? 803  ASN A O     1 
ATOM   4366  C  CB    . ASN A 1 785  ? 132.003 138.018 107.957 1.00 25.07  ? 803  ASN A CB    1 
ATOM   4367  C  CG    . ASN A 1 785  ? 132.654 139.280 108.486 1.00 25.07  ? 803  ASN A CG    1 
ATOM   4368  O  OD1   . ASN A 1 785  ? 133.855 139.306 108.757 1.00 25.07  ? 803  ASN A OD1   1 
ATOM   4369  N  ND2   . ASN A 1 785  ? 131.863 140.335 108.636 1.00 25.07  ? 803  ASN A ND2   1 
ATOM   4370  N  N     . ALA A 1 786  ? 130.178 135.237 108.582 1.00 18.74  ? 804  ALA A N     1 
ATOM   4371  C  CA    . ALA A 1 786  ? 129.608 134.075 107.912 1.00 18.74  ? 804  ALA A CA    1 
ATOM   4372  C  C     . ALA A 1 786  ? 128.869 133.147 108.866 1.00 18.74  ? 804  ALA A C     1 
ATOM   4373  O  O     . ALA A 1 786  ? 128.903 131.931 108.681 1.00 18.74  ? 804  ALA A O     1 
ATOM   4374  C  CB    . ALA A 1 786  ? 130.703 133.302 107.176 1.00 18.74  ? 804  ALA A CB    1 
ATOM   4375  N  N     . HIS A 1 787  ? 128.205 133.686 109.884 1.00 19.55  ? 805  HIS A N     1 
ATOM   4376  C  CA    . HIS A 1 787  ? 127.467 132.821 110.794 1.00 19.55  ? 805  HIS A CA    1 
ATOM   4377  C  C     . HIS A 1 787  ? 126.008 132.689 110.393 1.00 19.55  ? 805  HIS A C     1 
ATOM   4378  O  O     . HIS A 1 787  ? 125.331 131.758 110.838 1.00 19.55  ? 805  HIS A O     1 
ATOM   4379  C  CB    . HIS A 1 787  ? 127.579 133.336 112.230 1.00 19.55  ? 805  HIS A CB    1 
ATOM   4380  C  CG    . HIS A 1 787  ? 126.863 134.626 112.477 1.00 19.55  ? 805  HIS A CG    1 
ATOM   4381  N  ND1   . HIS A 1 787  ? 127.435 135.855 112.231 1.00 19.55  ? 805  HIS A ND1   1 
ATOM   4382  C  CD2   . HIS A 1 787  ? 125.627 134.878 112.968 1.00 19.55  ? 805  HIS A CD2   1 
ATOM   4383  C  CE1   . HIS A 1 787  ? 126.579 136.809 112.550 1.00 19.55  ? 805  HIS A CE1   1 
ATOM   4384  N  NE2   . HIS A 1 787  ? 125.474 136.243 113.000 1.00 19.55  ? 805  HIS A NE2   1 
ATOM   4385  N  N     . LYS A 1 788  ? 125.507 133.608 109.568 1.00 18.63  ? 806  LYS A N     1 
ATOM   4386  C  CA    . LYS A 1 788  ? 124.157 133.463 109.037 1.00 18.63  ? 806  LYS A CA    1 
ATOM   4387  C  C     . LYS A 1 788  ? 124.075 132.284 108.079 1.00 18.63  ? 806  LYS A C     1 
ATOM   4388  O  O     . LYS A 1 788  ? 123.134 131.487 108.135 1.00 18.63  ? 806  LYS A O     1 
ATOM   4389  C  CB    . LYS A 1 788  ? 123.729 134.753 108.339 1.00 18.63  ? 806  LYS A CB    1 
ATOM   4390  C  CG    . LYS A 1 788  ? 123.584 135.942 109.267 1.00 18.63  ? 806  LYS A CG    1 
ATOM   4391  C  CD    . LYS A 1 788  ? 122.501 135.692 110.299 1.00 18.63  ? 806  LYS A CD    1 
ATOM   4392  C  CE    . LYS A 1 788  ? 122.337 136.885 111.222 1.00 18.63  ? 806  LYS A CE    1 
ATOM   4393  N  NZ    . LYS A 1 788  ? 121.305 136.638 112.263 1.00 18.63  ? 806  LYS A NZ    1 
ATOM   4394  N  N     . ARG A 1 789  ? 125.053 132.167 107.179 1.00 18.94  ? 807  ARG A N     1 
ATOM   4395  C  CA    . ARG A 1 789  ? 125.048 131.077 106.211 1.00 18.94  ? 807  ARG A CA    1 
ATOM   4396  C  C     . ARG A 1 789  ? 125.212 129.727 106.896 1.00 18.94  ? 807  ARG A C     1 
ATOM   4397  O  O     . ARG A 1 789  ? 124.402 128.816 106.696 1.00 18.94  ? 807  ARG A O     1 
ATOM   4398  C  CB    . ARG A 1 789  ? 126.158 131.288 105.186 1.00 18.94  ? 807  ARG A CB    1 
ATOM   4399  C  CG    . ARG A 1 789  ? 126.199 132.682 104.608 1.00 18.94  ? 807  ARG A CG    1 
ATOM   4400  C  CD    . ARG A 1 789  ? 127.043 132.719 103.355 1.00 18.94  ? 807  ARG A CD    1 
ATOM   4401  N  NE    . ARG A 1 789  ? 128.426 132.348 103.620 1.00 18.94  ? 807  ARG A NE    1 
ATOM   4402  C  CZ    . ARG A 1 789  ? 129.429 133.211 103.701 1.00 18.94  ? 807  ARG A CZ    1 
ATOM   4403  N  NH1   . ARG A 1 789  ? 129.239 134.508 103.529 1.00 18.94  ? 807  ARG A NH1   1 
ATOM   4404  N  NH2   . ARG A 1 789  ? 130.653 132.760 103.955 1.00 18.94  ? 807  ARG A NH2   1 
ATOM   4405  N  N     . ILE A 1 790  ? 126.252 129.589 107.719 1.00 18.18  ? 808  ILE A N     1 
ATOM   4406  C  CA    . ILE A 1 790  ? 126.579 128.297 108.315 1.00 18.18  ? 808  ILE A CA    1 
ATOM   4407  C  C     . ILE A 1 790  ? 125.446 127.819 109.212 1.00 18.18  ? 808  ILE A C     1 
ATOM   4408  O  O     . ILE A 1 790  ? 125.043 126.652 109.166 1.00 18.18  ? 808  ILE A O     1 
ATOM   4409  C  CB    . ILE A 1 790  ? 127.910 128.388 109.079 1.00 18.18  ? 808  ILE A CB    1 
ATOM   4410  C  CG1   . ILE A 1 790  ? 129.016 128.854 108.137 1.00 18.18  ? 808  ILE A CG1   1 
ATOM   4411  C  CG2   . ILE A 1 790  ? 128.268 127.050 109.684 1.00 18.18  ? 808  ILE A CG2   1 
ATOM   4412  C  CD1   . ILE A 1 790  ? 130.341 129.033 108.807 1.00 18.18  ? 808  ILE A CD1   1 
ATOM   4413  N  N     . SER A 1 791  ? 124.910 128.717 110.039 1.00 17.25  ? 809  SER A N     1 
ATOM   4414  C  CA    . SER A 1 791  ? 123.839 128.335 110.948 1.00 17.25  ? 809  SER A CA    1 
ATOM   4415  C  C     . SER A 1 791  ? 122.548 128.009 110.213 1.00 17.25  ? 809  SER A C     1 
ATOM   4416  O  O     . SER A 1 791  ? 121.711 127.281 110.754 1.00 17.25  ? 809  SER A O     1 
ATOM   4417  C  CB    . SER A 1 791  ? 123.588 129.450 111.960 1.00 17.25  ? 809  SER A CB    1 
ATOM   4418  O  OG    . SER A 1 791  ? 124.808 129.935 112.492 1.00 17.25  ? 809  SER A OG    1 
ATOM   4419  N  N     . SER A 1 792  ? 122.373 128.528 109.002 1.00 16.33  ? 810  SER A N     1 
ATOM   4420  C  CA    . SER A 1 792  ? 121.167 128.311 108.217 1.00 16.33  ? 810  SER A CA    1 
ATOM   4421  C  C     . SER A 1 792  ? 121.314 127.206 107.183 1.00 16.33  ? 810  SER A C     1 
ATOM   4422  O  O     . SER A 1 792  ? 120.392 127.002 106.389 1.00 16.33  ? 810  SER A O     1 
ATOM   4423  C  CB    . SER A 1 792  ? 120.759 129.603 107.512 1.00 16.33  ? 810  SER A CB    1 
ATOM   4424  O  OG    . SER A 1 792  ? 121.787 130.029 106.638 1.00 16.33  ? 810  SER A OG    1 
ATOM   4425  N  N     . GLN A 1 793  ? 122.452 126.513 107.148 1.00 18.44  ? 811  GLN A N     1 
ATOM   4426  C  CA    . GLN A 1 793  ? 122.615 125.413 106.207 1.00 18.44  ? 811  GLN A CA    1 
ATOM   4427  C  C     . GLN A 1 793  ? 121.552 124.359 106.460 1.00 18.44  ? 811  GLN A C     1 
ATOM   4428  O  O     . GLN A 1 793  ? 121.321 123.952 107.602 1.00 18.44  ? 811  GLN A O     1 
ATOM   4429  C  CB    . GLN A 1 793  ? 124.008 124.800 106.330 1.00 18.44  ? 811  GLN A CB    1 
ATOM   4430  C  CG    . GLN A 1 793  ? 125.149 125.773 106.122 1.00 18.44  ? 811  GLN A CG    1 
ATOM   4431  C  CD    . GLN A 1 793  ? 125.432 126.071 104.664 1.00 18.44  ? 811  GLN A CD    1 
ATOM   4432  O  OE1   . GLN A 1 793  ? 126.374 126.792 104.345 1.00 18.44  ? 811  GLN A OE1   1 
ATOM   4433  N  NE2   . GLN A 1 793  ? 124.625 125.512 103.770 1.00 18.44  ? 811  GLN A NE2   1 
ATOM   4434  N  N     . MET A 1 794  ? 120.901 123.916 105.388 1.00 19.25  ? 812  MET A N     1 
ATOM   4435  C  CA    . MET A 1 794  ? 119.729 123.056 105.511 1.00 19.25  ? 812  MET A CA    1 
ATOM   4436  C  C     . MET A 1 794  ? 120.191 121.615 105.709 1.00 19.25  ? 812  MET A C     1 
ATOM   4437  O  O     . MET A 1 794  ? 120.191 120.788 104.794 1.00 19.25  ? 812  MET A O     1 
ATOM   4438  C  CB    . MET A 1 794  ? 118.828 123.201 104.293 1.00 19.25  ? 812  MET A CB    1 
ATOM   4439  C  CG    . MET A 1 794  ? 117.490 122.541 104.479 1.00 19.25  ? 812  MET A CG    1 
ATOM   4440  S  SD    . MET A 1 794  ? 116.724 122.055 102.935 1.00 19.25  ? 812  MET A SD    1 
ATOM   4441  C  CE    . MET A 1 794  ? 115.860 120.590 103.480 1.00 19.25  ? 812  MET A CE    1 
ATOM   4442  N  N     . VAL A 1 795  ? 120.601 121.321 106.941 1.00 17.14  ? 813  VAL A N     1 
ATOM   4443  C  CA    . VAL A 1 795  ? 120.936 119.956 107.316 1.00 17.14  ? 813  VAL A CA    1 
ATOM   4444  C  C     . VAL A 1 795  ? 119.670 119.117 107.363 1.00 17.14  ? 813  VAL A C     1 
ATOM   4445  O  O     . VAL A 1 795  ? 118.584 119.610 107.686 1.00 17.14  ? 813  VAL A O     1 
ATOM   4446  C  CB    . VAL A 1 795  ? 121.655 119.931 108.675 1.00 17.14  ? 813  VAL A CB    1 
ATOM   4447  C  CG1   . VAL A 1 795  ? 122.356 118.602 108.885 1.00 17.14  ? 813  VAL A CG1   1 
ATOM   4448  C  CG2   . VAL A 1 795  ? 122.620 121.088 108.779 1.00 17.14  ? 813  VAL A CG2   1 
ATOM   4449  N  N     . VAL A 1 796  ? 119.804 117.836 107.043 1.00 18.56  ? 814  VAL A N     1 
ATOM   4450  C  CA    . VAL A 1 796  ? 118.719 116.880 107.203 1.00 18.56  ? 814  VAL A CA    1 
ATOM   4451  C  C     . VAL A 1 796  ? 119.286 115.649 107.888 1.00 18.56  ? 814  VAL A C     1 
ATOM   4452  O  O     . VAL A 1 796  ? 120.211 115.018 107.366 1.00 18.56  ? 814  VAL A O     1 
ATOM   4453  C  CB    . VAL A 1 796  ? 118.061 116.515 105.863 1.00 18.56  ? 814  VAL A CB    1 
ATOM   4454  C  CG1   . VAL A 1 796  ? 117.366 115.178 105.962 1.00 18.56  ? 814  VAL A CG1   1 
ATOM   4455  C  CG2   . VAL A 1 796  ? 117.066 117.585 105.470 1.00 18.56  ? 814  VAL A CG2   1 
ATOM   4456  N  N     . TRP A 1 797  ? 118.740 115.315 109.054 1.00 24.59  ? 815  TRP A N     1 
ATOM   4457  C  CA    . TRP A 1 797  ? 119.224 114.196 109.852 1.00 24.59  ? 815  TRP A CA    1 
ATOM   4458  C  C     . TRP A 1 797  ? 118.467 112.934 109.465 1.00 24.59  ? 815  TRP A C     1 
ATOM   4459  O  O     . TRP A 1 797  ? 117.239 112.881 109.585 1.00 24.59  ? 815  TRP A O     1 
ATOM   4460  C  CB    . TRP A 1 797  ? 119.044 114.468 111.343 1.00 24.59  ? 815  TRP A CB    1 
ATOM   4461  C  CG    . TRP A 1 797  ? 119.436 115.833 111.780 1.00 24.59  ? 815  TRP A CG    1 
ATOM   4462  C  CD1   . TRP A 1 797  ? 118.600 116.851 112.116 1.00 24.59  ? 815  TRP A CD1   1 
ATOM   4463  C  CD2   . TRP A 1 797  ? 120.765 116.334 111.945 1.00 24.59  ? 815  TRP A CD2   1 
ATOM   4464  N  NE1   . TRP A 1 797  ? 119.323 117.959 112.479 1.00 24.59  ? 815  TRP A NE1   1 
ATOM   4465  C  CE2   . TRP A 1 797  ? 120.657 117.667 112.382 1.00 24.59  ? 815  TRP A CE2   1 
ATOM   4466  C  CE3   . TRP A 1 797  ? 122.037 115.785 111.766 1.00 24.59  ? 815  TRP A CE3   1 
ATOM   4467  C  CZ2   . TRP A 1 797  ? 121.773 118.461 112.640 1.00 24.59  ? 815  TRP A CZ2   1 
ATOM   4468  C  CZ3   . TRP A 1 797  ? 123.142 116.575 112.021 1.00 24.59  ? 815  TRP A CZ3   1 
ATOM   4469  C  CH2   . TRP A 1 797  ? 123.004 117.897 112.454 1.00 24.59  ? 815  TRP A CH2   1 
ATOM   4470  N  N     . LEU A 1 798  ? 119.174 111.954 109.033 1.00 29.87  ? 816  LEU A N     1 
ATOM   4471  C  CA    . LEU A 1 798  ? 118.419 110.749 108.743 1.00 29.87  ? 816  LEU A CA    1 
ATOM   4472  C  C     . LEU A 1 798  ? 118.210 109.932 110.011 1.00 29.87  ? 816  LEU A C     1 
ATOM   4473  O  O     . LEU A 1 798  ? 119.033 109.975 110.930 1.00 29.87  ? 816  LEU A O     1 
ATOM   4474  C  CB    . LEU A 1 798  ? 119.149 109.896 107.712 1.00 29.87  ? 816  LEU A CB    1 
ATOM   4475  C  CG    . LEU A 1 798  ? 119.527 110.541 106.382 1.00 29.87  ? 816  LEU A CG    1 
ATOM   4476  C  CD1   . LEU A 1 798  ? 120.077 109.488 105.437 1.00 29.87  ? 816  LEU A CD1   1 
ATOM   4477  C  CD2   . LEU A 1 798  ? 118.327 111.242 105.777 1.00 29.87  ? 816  LEU A CD2   1 
ATOM   4478  N  N     . PRO A 1 799  ? 117.127 109.179 110.083 1.00 44.09  ? 817  PRO A N     1 
ATOM   4479  C  CA    . PRO A 1 799  ? 116.963 108.240 111.198 1.00 44.09  ? 817  PRO A CA    1 
ATOM   4480  C  C     . PRO A 1 799  ? 117.633 106.911 110.895 1.00 44.09  ? 817  PRO A C     1 
ATOM   4481  O  O     . PRO A 1 799  ? 118.281 106.764 109.854 1.00 44.09  ? 817  PRO A O     1 
ATOM   4482  C  CB    . PRO A 1 799  ? 115.443 108.105 111.312 1.00 44.09  ? 817  PRO A CB    1 
ATOM   4483  C  CG    . PRO A 1 799  ? 114.963 108.298 109.911 1.00 44.09  ? 817  PRO A CG    1 
ATOM   4484  C  CD    . PRO A 1 799  ? 115.911 109.277 109.258 1.00 44.09  ? 817  PRO A CD    1 
ATOM   4485  N  N     . ARG A 1 800  ? 117.499 105.937 111.796 1.00 55.73  ? 818  ARG A N     1 
ATOM   4486  C  CA    . ARG A 1 800  ? 118.025 104.609 111.512 1.00 55.73  ? 818  ARG A CA    1 
ATOM   4487  C  C     . ARG A 1 800  ? 117.264 103.911 110.394 1.00 55.73  ? 818  ARG A C     1 
ATOM   4488  O  O     . ARG A 1 800  ? 117.736 102.886 109.893 1.00 55.73  ? 818  ARG A O     1 
ATOM   4489  C  CB    . ARG A 1 800  ? 117.993 103.739 112.769 1.00 55.73  ? 818  ARG A CB    1 
ATOM   4490  C  CG    . ARG A 1 800  ? 116.602 103.274 113.165 1.00 55.73  ? 818  ARG A CG    1 
ATOM   4491  C  CD    . ARG A 1 800  ? 116.650 101.911 113.835 1.00 55.73  ? 818  ARG A CD    1 
ATOM   4492  N  NE    . ARG A 1 800  ? 117.360 100.936 113.015 1.00 55.73  ? 818  ARG A NE    1 
ATOM   4493  C  CZ    . ARG A 1 800  ? 116.820 100.272 112.003 1.00 55.73  ? 818  ARG A CZ    1 
ATOM   4494  N  NH1   . ARG A 1 800  ? 115.555 100.449 111.656 1.00 55.73  ? 818  ARG A NH1   1 
ATOM   4495  N  NH2   . ARG A 1 800  ? 117.567 99.411  111.318 1.00 55.73  ? 818  ARG A NH2   1 
ATOM   4496  N  N     . SER A 1 801  ? 116.105 104.440 109.996 1.00 61.34  ? 819  SER A N     1 
ATOM   4497  C  CA    . SER A 1 801  ? 115.297 103.837 108.944 1.00 61.34  ? 819  SER A CA    1 
ATOM   4498  C  C     . SER A 1 801  ? 115.885 104.031 107.554 1.00 61.34  ? 819  SER A C     1 
ATOM   4499  O  O     . SER A 1 801  ? 115.389 103.419 106.603 1.00 61.34  ? 819  SER A O     1 
ATOM   4500  C  CB    . SER A 1 801  ? 113.880 104.412 108.985 1.00 61.34  ? 819  SER A CB    1 
ATOM   4501  O  OG    . SER A 1 801  ? 113.315 104.276 110.277 1.00 61.34  ? 819  SER A OG    1 
ATOM   4502  N  N     . ALA A 1 802  ? 116.919 104.860 107.407 1.00 59.02  ? 820  ALA A N     1 
ATOM   4503  C  CA    . ALA A 1 802  ? 117.504 105.120 106.101 1.00 59.02  ? 820  ALA A CA    1 
ATOM   4504  C  C     . ALA A 1 802  ? 119.018 104.994 106.058 1.00 59.02  ? 820  ALA A C     1 
ATOM   4505  O  O     . ALA A 1 802  ? 119.590 105.092 104.966 1.00 59.02  ? 820  ALA A O     1 
ATOM   4506  C  CB    . ALA A 1 802  ? 117.113 106.522 105.606 1.00 59.02  ? 820  ALA A CB    1 
ATOM   4507  N  N     . LEU A 1 803  ? 119.684 104.785 107.190 1.00 56.79  ? 821  LEU A N     1 
ATOM   4508  C  CA    . LEU A 1 803  ? 121.127 104.613 107.176 1.00 56.79  ? 821  LEU A CA    1 
ATOM   4509  C  C     . LEU A 1 803  ? 121.496 103.267 106.553 1.00 56.79  ? 821  LEU A C     1 
ATOM   4510  O  O     . LEU A 1 803  ? 120.741 102.297 106.656 1.00 56.79  ? 821  LEU A O     1 
ATOM   4511  C  CB    . LEU A 1 803  ? 121.692 104.709 108.591 1.00 56.79  ? 821  LEU A CB    1 
ATOM   4512  C  CG    . LEU A 1 803  ? 121.726 106.107 109.208 1.00 56.79  ? 821  LEU A CG    1 
ATOM   4513  C  CD1   . LEU A 1 803  ? 122.114 106.032 110.673 1.00 56.79  ? 821  LEU A CD1   1 
ATOM   4514  C  CD2   . LEU A 1 803  ? 122.691 106.998 108.445 1.00 56.79  ? 821  LEU A CD2   1 
ATOM   4515  N  N     . PRO A 1 804  ? 122.647 103.187 105.890 1.00 57.80  ? 822  PRO A N     1 
ATOM   4516  C  CA    . PRO A 1 804  ? 123.053 101.925 105.265 1.00 57.80  ? 822  PRO A CA    1 
ATOM   4517  C  C     . PRO A 1 804  ? 123.382 100.863 106.302 1.00 57.80  ? 822  PRO A C     1 
ATOM   4518  O  O     . PRO A 1 804  ? 123.701 101.152 107.458 1.00 57.80  ? 822  PRO A O     1 
ATOM   4519  C  CB    . PRO A 1 804  ? 124.300 102.308 104.457 1.00 57.80  ? 822  PRO A CB    1 
ATOM   4520  C  CG    . PRO A 1 804  ? 124.244 103.793 104.327 1.00 57.80  ? 822  PRO A CG    1 
ATOM   4521  C  CD    . PRO A 1 804  ? 123.579 104.280 105.572 1.00 57.80  ? 822  PRO A CD    1 
ATOM   4522  N  N     . ARG A 1 805  ? 123.289 99.605  105.862 1.00 68.05  ? 823  ARG A N     1 
ATOM   4523  C  CA    . ARG A 1 805  ? 123.683 98.489  106.715 1.00 68.05  ? 823  ARG A CA    1 
ATOM   4524  C  C     . ARG A 1 805  ? 125.152 98.583  107.112 1.00 68.05  ? 823  ARG A C     1 
ATOM   4525  O  O     . ARG A 1 805  ? 125.541 98.092  108.177 1.00 68.05  ? 823  ARG A O     1 
ATOM   4526  C  CB    . ARG A 1 805  ? 123.400 97.165  106.003 1.00 68.05  ? 823  ARG A CB    1 
ATOM   4527  C  CG    . ARG A 1 805  ? 123.820 95.930  106.782 1.00 68.05  ? 823  ARG A CG    1 
ATOM   4528  C  CD    . ARG A 1 805  ? 123.513 94.651  106.021 1.00 68.05  ? 823  ARG A CD    1 
ATOM   4529  N  NE    . ARG A 1 805  ? 122.080 94.399  105.930 1.00 68.05  ? 823  ARG A NE    1 
ATOM   4530  C  CZ    . ARG A 1 805  ? 121.364 93.810  106.877 1.00 68.05  ? 823  ARG A CZ    1 
ATOM   4531  N  NH1   . ARG A 1 805  ? 121.915 93.407  108.010 1.00 68.05  ? 823  ARG A NH1   1 
ATOM   4532  N  NH2   . ARG A 1 805  ? 120.061 93.625  106.684 1.00 68.05  ? 823  ARG A NH2   1 
ATOM   4533  N  N     . ALA A 1 806  ? 125.973 99.232  106.289 1.00 53.85  ? 824  ALA A N     1 
ATOM   4534  C  CA    . ALA A 1 806  ? 127.391 99.416  106.583 1.00 53.85  ? 824  ALA A CA    1 
ATOM   4535  C  C     . ALA A 1 806  ? 127.641 100.455 107.661 1.00 53.85  ? 824  ALA A C     1 
ATOM   4536  O  O     . ALA A 1 806  ? 128.795 100.850 107.872 1.00 53.85  ? 824  ALA A O     1 
ATOM   4537  C  CB    . ALA A 1 806  ? 128.145 99.798  105.309 1.00 53.85  ? 824  ALA A CB    1 
ATOM   4538  N  N     . VAL A 1 807  ? 126.590 100.911 108.342 1.00 55.60  ? 825  VAL A N     1 
ATOM   4539  C  CA    . VAL A 1 807  ? 126.704 101.827 109.470 1.00 55.60  ? 825  VAL A CA    1 
ATOM   4540  C  C     . VAL A 1 807  ? 126.153 101.204 110.747 1.00 55.60  ? 825  VAL A C     1 
ATOM   4541  O  O     . VAL A 1 807  ? 126.799 101.245 111.798 1.00 55.60  ? 825  VAL A O     1 
ATOM   4542  C  CB    . VAL A 1 807  ? 126.008 103.174 109.173 1.00 55.60  ? 825  VAL A CB    1 
ATOM   4543  C  CG1   . VAL A 1 807  ? 125.879 103.997 110.443 1.00 55.60  ? 825  VAL A CG1   1 
ATOM   4544  C  CG2   . VAL A 1 807  ? 126.783 103.945 108.118 1.00 55.60  ? 825  VAL A CG2   1 
ATOM   4545  N  N     . ILE A 1 808  ? 124.962 100.603 110.670 1.00 63.39  ? 826  ILE A N     1 
ATOM   4546  C  CA    . ILE A 1 808  ? 124.352 100.000 111.854 1.00 63.39  ? 826  ILE A CA    1 
ATOM   4547  C  C     . ILE A 1 808  ? 125.232 98.881  112.399 1.00 63.39  ? 826  ILE A C     1 
ATOM   4548  O  O     . ILE A 1 808  ? 125.464 98.787  113.610 1.00 63.39  ? 826  ILE A O     1 
ATOM   4549  C  CB    . ILE A 1 808  ? 122.929 99.499  111.533 1.00 63.39  ? 826  ILE A CB    1 
ATOM   4550  C  CG1   . ILE A 1 808  ? 121.904 100.628 111.681 1.00 63.39  ? 826  ILE A CG1   1 
ATOM   4551  C  CG2   . ILE A 1 808  ? 122.545 98.334  112.433 1.00 63.39  ? 826  ILE A CG2   1 
ATOM   4552  C  CD1   . ILE A 1 808  ? 121.932 101.645 110.567 1.00 63.39  ? 826  ILE A CD1   1 
ATOM   4553  N  N     . ARG A 1 809  ? 125.745 98.021  111.516 1.00 65.98  ? 827  ARG A N     1 
ATOM   4554  C  CA    . ARG A 1 809  ? 126.594 96.923  111.960 1.00 65.98  ? 827  ARG A CA    1 
ATOM   4555  C  C     . ARG A 1 809  ? 127.954 97.399  112.452 1.00 65.98  ? 827  ARG A C     1 
ATOM   4556  O  O     . ARG A 1 809  ? 128.577 96.710  113.268 1.00 65.98  ? 827  ARG A O     1 
ATOM   4557  C  CB    . ARG A 1 809  ? 126.784 95.911  110.832 1.00 65.98  ? 827  ARG A CB    1 
ATOM   4558  C  CG    . ARG A 1 809  ? 125.500 95.270  110.348 1.00 65.98  ? 827  ARG A CG    1 
ATOM   4559  C  CD    . ARG A 1 809  ? 125.797 94.210  109.307 1.00 65.98  ? 827  ARG A CD    1 
ATOM   4560  N  NE    . ARG A 1 809  ? 126.636 94.731  108.235 1.00 65.98  ? 827  ARG A NE    1 
ATOM   4561  C  CZ    . ARG A 1 809  ? 127.050 94.022  107.194 1.00 65.98  ? 827  ARG A CZ    1 
ATOM   4562  N  NH1   . ARG A 1 809  ? 126.719 92.749  107.049 1.00 65.98  ? 827  ARG A NH1   1 
ATOM   4563  N  NH2   . ARG A 1 809  ? 127.815 94.604  106.275 1.00 65.98  ? 827  ARG A NH2   1 
ATOM   4564  N  N     . HIS A 1 810  ? 128.429 98.542  111.976 1.00 51.52  ? 828  HIS A N     1 
ATOM   4565  C  CA    . HIS A 1 810  ? 129.735 99.035  112.394 1.00 51.52  ? 828  HIS A CA    1 
ATOM   4566  C  C     . HIS A 1 810  ? 129.696 99.405  113.872 1.00 51.52  ? 828  HIS A C     1 
ATOM   4567  O  O     . HIS A 1 810  ? 128.792 100.133 114.300 1.00 51.52  ? 828  HIS A O     1 
ATOM   4568  C  CB    . HIS A 1 810  ? 130.145 100.238 111.552 1.00 51.52  ? 828  HIS A CB    1 
ATOM   4569  C  CG    . HIS A 1 810  ? 131.597 100.580 111.656 1.00 51.52  ? 828  HIS A CG    1 
ATOM   4570  N  ND1   . HIS A 1 810  ? 132.113 101.328 112.693 1.00 51.52  ? 828  HIS A ND1   1 
ATOM   4571  C  CD2   . HIS A 1 810  ? 132.645 100.279 110.854 1.00 51.52  ? 828  HIS A CD2   1 
ATOM   4572  C  CE1   . HIS A 1 810  ? 133.415 101.472 112.524 1.00 51.52  ? 828  HIS A CE1   1 
ATOM   4573  N  NE2   . HIS A 1 810  ? 133.763 100.845 111.415 1.00 51.52  ? 828  HIS A NE2   1 
ATOM   4574  N  N     . PRO A 1 811  ? 130.643 98.923  114.681 1.00 56.53  ? 829  PRO A N     1 
ATOM   4575  C  CA    . PRO A 1 811  ? 130.571 99.168  116.131 1.00 56.53  ? 829  PRO A CA    1 
ATOM   4576  C  C     . PRO A 1 811  ? 130.669 100.632 116.523 1.00 56.53  ? 829  PRO A C     1 
ATOM   4577  O  O     . PRO A 1 811  ? 130.239 100.987 117.628 1.00 56.53  ? 829  PRO A O     1 
ATOM   4578  C  CB    . PRO A 1 811  ? 131.757 98.363  116.680 1.00 56.53  ? 829  PRO A CB    1 
ATOM   4579  C  CG    . PRO A 1 811  ? 132.696 98.241  115.526 1.00 56.53  ? 829  PRO A CG    1 
ATOM   4580  C  CD    . PRO A 1 811  ? 131.827 98.132  114.311 1.00 56.53  ? 829  PRO A CD    1 
ATOM   4581  N  N     . ASP A 1 812  ? 131.218 101.495 115.667 1.00 57.35  ? 830  ASP A N     1 
ATOM   4582  C  CA    . ASP A 1 812  ? 131.332 102.909 116.004 1.00 57.35  ? 830  ASP A CA    1 
ATOM   4583  C  C     . ASP A 1 812  ? 129.989 103.629 115.973 1.00 57.35  ? 830  ASP A C     1 
ATOM   4584  O  O     . ASP A 1 812  ? 129.914 104.786 116.400 1.00 57.35  ? 830  ASP A O     1 
ATOM   4585  C  CB    . ASP A 1 812  ? 132.317 103.595 115.056 1.00 57.35  ? 830  ASP A CB    1 
ATOM   4586  C  CG    . ASP A 1 812  ? 132.891 104.876 115.632 1.00 57.35  ? 830  ASP A CG    1 
ATOM   4587  O  OD1   . ASP A 1 812  ? 132.654 105.156 116.825 1.00 57.35  ? 830  ASP A OD1   1 
ATOM   4588  O  OD2   . ASP A 1 812  ? 133.583 105.603 114.889 1.00 57.35  ? 830  ASP A OD2   1 
ATOM   4589  N  N     . TYR A 1 813  ? 128.936 102.979 115.485 1.00 60.37  ? 831  TYR A N     1 
ATOM   4590  C  CA    . TYR A 1 813  ? 127.612 103.582 115.443 1.00 60.37  ? 831  TYR A CA    1 
ATOM   4591  C  C     . TYR A 1 813  ? 126.946 103.499 116.810 1.00 60.37  ? 831  TYR A C     1 
ATOM   4592  O  O     . TYR A 1 813  ? 126.955 102.445 117.454 1.00 60.37  ? 831  TYR A O     1 
ATOM   4593  C  CB    . TYR A 1 813  ? 126.753 102.884 114.391 1.00 60.37  ? 831  TYR A CB    1 
ATOM   4594  C  CG    . TYR A 1 813  ? 125.263 103.017 114.598 1.00 60.37  ? 831  TYR A CG    1 
ATOM   4595  C  CD1   . TYR A 1 813  ? 124.594 104.179 114.246 1.00 60.37  ? 831  TYR A CD1   1 
ATOM   4596  C  CD2   . TYR A 1 813  ? 124.521 101.971 115.127 1.00 60.37  ? 831  TYR A CD2   1 
ATOM   4597  C  CE1   . TYR A 1 813  ? 123.230 104.301 114.427 1.00 60.37  ? 831  TYR A CE1   1 
ATOM   4598  C  CE2   . TYR A 1 813  ? 123.158 102.084 115.312 1.00 60.37  ? 831  TYR A CE2   1 
ATOM   4599  C  CZ    . TYR A 1 813  ? 122.518 103.250 114.960 1.00 60.37  ? 831  TYR A CZ    1 
ATOM   4600  O  OH    . TYR A 1 813  ? 121.160 103.363 115.143 1.00 60.37  ? 831  TYR A OH    1 
ATOM   4601  N  N     . ASP A 1 814  ? 126.364 104.612 117.248 1.00 65.03  ? 832  ASP A N     1 
ATOM   4602  C  CA    . ASP A 1 814  ? 125.651 104.687 118.513 1.00 65.03  ? 832  ASP A CA    1 
ATOM   4603  C  C     . ASP A 1 814  ? 124.209 105.102 118.261 1.00 65.03  ? 832  ASP A C     1 
ATOM   4604  O  O     . ASP A 1 814  ? 123.939 105.966 117.422 1.00 65.03  ? 832  ASP A O     1 
ATOM   4605  C  CB    . ASP A 1 814  ? 126.325 105.672 119.475 1.00 65.03  ? 832  ASP A CB    1 
ATOM   4606  C  CG    . ASP A 1 814  ? 126.661 106.995 118.817 1.00 65.03  ? 832  ASP A CG    1 
ATOM   4607  O  OD1   . ASP A 1 814  ? 126.500 107.109 117.585 1.00 65.03  ? 832  ASP A OD1   1 
ATOM   4608  O  OD2   . ASP A 1 814  ? 127.089 107.923 119.534 1.00 65.03  ? 832  ASP A OD2   1 
ATOM   4609  N  N     . GLU A 1 815  ? 123.283 104.478 118.991 1.00 72.75  ? 833  GLU A N     1 
ATOM   4610  C  CA    . GLU A 1 815  ? 121.864 104.753 118.804 1.00 72.75  ? 833  GLU A CA    1 
ATOM   4611  C  C     . GLU A 1 815  ? 121.463 106.148 119.261 1.00 72.75  ? 833  GLU A C     1 
ATOM   4612  O  O     . GLU A 1 815  ? 120.342 106.575 118.967 1.00 72.75  ? 833  GLU A O     1 
ATOM   4613  C  CB    . GLU A 1 815  ? 121.021 103.711 119.545 1.00 72.75  ? 833  GLU A CB    1 
ATOM   4614  C  CG    . GLU A 1 815  ? 121.037 102.319 118.922 1.00 72.75  ? 833  GLU A CG    1 
ATOM   4615  C  CD    . GLU A 1 815  ? 122.305 101.544 119.231 1.00 72.75  ? 833  GLU A CD    1 
ATOM   4616  O  OE1   . GLU A 1 815  ? 123.138 102.046 120.016 1.00 72.75  ? 833  GLU A OE1   1 
ATOM   4617  O  OE2   . GLU A 1 815  ? 122.467 100.430 118.690 1.00 72.75  ? 833  GLU A OE2   1 
ATOM   4618  N  N     . GLU A 1 816  ? 122.336 106.865 119.966 1.00 69.86  ? 834  GLU A N     1 
ATOM   4619  C  CA    . GLU A 1 816  ? 122.031 108.198 120.463 1.00 69.86  ? 834  GLU A CA    1 
ATOM   4620  C  C     . GLU A 1 816  ? 122.690 109.298 119.641 1.00 69.86  ? 834  GLU A C     1 
ATOM   4621  O  O     . GLU A 1 816  ? 122.815 110.428 120.123 1.00 69.86  ? 834  GLU A O     1 
ATOM   4622  C  CB    . GLU A 1 816  ? 122.444 108.321 121.931 1.00 69.86  ? 834  GLU A CB    1 
ATOM   4623  C  CG    . GLU A 1 816  ? 121.844 107.251 122.834 1.00 69.86  ? 834  GLU A CG    1 
ATOM   4624  C  CD    . GLU A 1 816  ? 120.325 107.292 122.875 1.00 69.86  ? 834  GLU A CD    1 
ATOM   4625  O  OE1   . GLU A 1 816  ? 119.747 108.381 122.674 1.00 69.86  ? 834  GLU A OE1   1 
ATOM   4626  O  OE2   . GLU A 1 816  ? 119.709 106.231 123.108 1.00 69.86  ? 834  GLU A OE2   1 
ATOM   4627  N  N     . GLY A 1 817  ? 123.117 108.996 118.421 1.00 52.36  ? 835  GLY A N     1 
ATOM   4628  C  CA    . GLY A 1 817  ? 123.684 109.984 117.515 1.00 52.36  ? 835  GLY A CA    1 
ATOM   4629  C  C     . GLY A 1 817  ? 122.833 110.094 116.262 1.00 52.36  ? 835  GLY A C     1 
ATOM   4630  O  O     . GLY A 1 817  ? 122.377 109.083 115.722 1.00 52.36  ? 835  GLY A O     1 
ATOM   4631  N  N     . LEU A 1 818  ? 122.622 111.325 115.808 1.00 36.91  ? 836  LEU A N     1 
ATOM   4632  C  CA    . LEU A 1 818  ? 121.829 111.594 114.615 1.00 36.91  ? 836  LEU A CA    1 
ATOM   4633  C  C     . LEU A 1 818  ? 122.763 111.791 113.429 1.00 36.91  ? 836  LEU A C     1 
ATOM   4634  O  O     . LEU A 1 818  ? 123.656 112.644 113.471 1.00 36.91  ? 836  LEU A O     1 
ATOM   4635  C  CB    . LEU A 1 818  ? 120.941 112.823 114.809 1.00 36.91  ? 836  LEU A CB    1 
ATOM   4636  C  CG    . LEU A 1 818  ? 119.496 112.567 115.242 1.00 36.91  ? 836  LEU A CG    1 
ATOM   4637  C  CD1   . LEU A 1 818  ? 118.771 113.879 115.487 1.00 36.91  ? 836  LEU A CD1   1 
ATOM   4638  C  CD2   . LEU A 1 818  ? 118.764 111.740 114.199 1.00 36.91  ? 836  LEU A CD2   1 
ATOM   4639  N  N     . TYR A 1 819  ? 122.551 111.006 112.379 1.00 38.47  ? 837  TYR A N     1 
ATOM   4640  C  CA    . TYR A 1 819  ? 123.327 111.087 111.154 1.00 38.47  ? 837  TYR A CA    1 
ATOM   4641  C  C     . TYR A 1 819  ? 122.472 111.684 110.048 1.00 38.47  ? 837  TYR A C     1 
ATOM   4642  O  O     . TYR A 1 819  ? 121.253 111.499 110.016 1.00 38.47  ? 837  TYR A O     1 
ATOM   4643  C  CB    . TYR A 1 819  ? 123.836 109.708 110.726 1.00 38.47  ? 837  TYR A CB    1 
ATOM   4644  C  CG    . TYR A 1 819  ? 124.739 109.052 111.741 1.00 38.47  ? 837  TYR A CG    1 
ATOM   4645  C  CD1   . TYR A 1 819  ? 126.090 109.364 111.799 1.00 38.47  ? 837  TYR A CD1   1 
ATOM   4646  C  CD2   . TYR A 1 819  ? 124.241 108.121 112.643 1.00 38.47  ? 837  TYR A CD2   1 
ATOM   4647  C  CE1   . TYR A 1 819  ? 126.920 108.769 112.728 1.00 38.47  ? 837  TYR A CE1   1 
ATOM   4648  C  CE2   . TYR A 1 819  ? 125.064 107.521 113.575 1.00 38.47  ? 837  TYR A CE2   1 
ATOM   4649  C  CZ    . TYR A 1 819  ? 126.401 107.847 113.612 1.00 38.47  ? 837  TYR A CZ    1 
ATOM   4650  O  OH    . TYR A 1 819  ? 127.223 107.250 114.539 1.00 38.47  ? 837  TYR A OH    1 
ATOM   4651  N  N     . GLY A 1 820  ? 123.113 112.407 109.155 1.00 22.87  ? 838  GLY A N     1 
ATOM   4652  C  CA    . GLY A 1 820  ? 122.425 112.999 108.026 1.00 22.87  ? 838  GLY A CA    1 
ATOM   4653  C  C     . GLY A 1 820  ? 123.396 113.420 106.963 1.00 22.87  ? 838  GLY A C     1 
ATOM   4654  O  O     . GLY A 1 820  ? 124.411 112.760 106.729 1.00 22.87  ? 838  GLY A O     1 
ATOM   4655  N  N     . ALA A 1 821  ? 123.087 114.537 106.312 1.00 15.16  ? 839  ALA A N     1 
ATOM   4656  C  CA    . ALA A 1 821  ? 123.937 115.061 105.256 1.00 15.16  ? 839  ALA A CA    1 
ATOM   4657  C  C     . ALA A 1 821  ? 123.540 116.494 104.962 1.00 15.16  ? 839  ALA A C     1 
ATOM   4658  O  O     . ALA A 1 821  ? 122.440 116.936 105.295 1.00 15.16  ? 839  ALA A O     1 
ATOM   4659  C  CB    . ALA A 1 821  ? 123.841 114.219 103.984 1.00 15.16  ? 839  ALA A CB    1 
ATOM   4660  N  N     . ILE A 1 822  ? 124.462 117.211 104.334 1.00 16.37  ? 840  ILE A N     1 
ATOM   4661  C  CA    . ILE A 1 822  ? 124.215 118.541 103.797 1.00 16.37  ? 840  ILE A CA    1 
ATOM   4662  C  C     . ILE A 1 822  ? 124.472 118.473 102.300 1.00 16.37  ? 840  ILE A C     1 
ATOM   4663  O  O     . ILE A 1 822  ? 125.571 118.100 101.870 1.00 16.37  ? 840  ILE A O     1 
ATOM   4664  C  CB    . ILE A 1 822  ? 125.100 119.604 104.463 1.00 16.37  ? 840  ILE A CB    1 
ATOM   4665  C  CG1   . ILE A 1 822  ? 124.705 119.785 105.923 1.00 16.37  ? 840  ILE A CG1   1 
ATOM   4666  C  CG2   . ILE A 1 822  ? 124.999 120.926 103.732 1.00 16.37  ? 840  ILE A CG2   1 
ATOM   4667  C  CD1   . ILE A 1 822  ? 125.443 120.898 106.604 1.00 16.37  ? 840  ILE A CD1   1 
ATOM   4668  N  N     . LEU A 1 823  ? 123.460 118.806 101.513 1.00 13.08  ? 841  LEU A N     1 
ATOM   4669  C  CA    . LEU A 1 823  ? 123.582 118.829 100.063 1.00 13.08  ? 841  LEU A CA    1 
ATOM   4670  C  C     . LEU A 1 823  ? 123.885 120.251 99.631  1.00 13.08  ? 841  LEU A C     1 
ATOM   4671  O  O     . LEU A 1 823  ? 122.968 121.075 99.537  1.00 13.08  ? 841  LEU A O     1 
ATOM   4672  C  CB    . LEU A 1 823  ? 122.301 118.341 99.395  1.00 13.08  ? 841  LEU A CB    1 
ATOM   4673  C  CG    . LEU A 1 823  ? 122.118 116.851 99.119  1.00 13.08  ? 841  LEU A CG    1 
ATOM   4674  C  CD1   . LEU A 1 823  ? 122.628 115.990 100.254 1.00 13.08  ? 841  LEU A CD1   1 
ATOM   4675  C  CD2   . LEU A 1 823  ? 120.654 116.587 98.884  1.00 13.08  ? 841  LEU A CD2   1 
ATOM   4676  N  N     . PRO A 1 824  ? 125.147 120.577 99.367  1.00 16.39  ? 842  PRO A N     1 
ATOM   4677  C  CA    . PRO A 1 824  ? 125.502 121.969 99.085  1.00 16.39  ? 842  PRO A CA    1 
ATOM   4678  C  C     . PRO A 1 824  ? 124.701 122.513 97.914  1.00 16.39  ? 842  PRO A C     1 
ATOM   4679  O  O     . PRO A 1 824  ? 124.484 121.832 96.910  1.00 16.39  ? 842  PRO A O     1 
ATOM   4680  C  CB    . PRO A 1 824  ? 126.997 121.891 98.757  1.00 16.39  ? 842  PRO A CB    1 
ATOM   4681  C  CG    . PRO A 1 824  ? 127.459 120.634 99.375  1.00 16.39  ? 842  PRO A CG    1 
ATOM   4682  C  CD    . PRO A 1 824  ? 126.310 119.685 99.266  1.00 16.39  ? 842  PRO A CD    1 
ATOM   4683  N  N     . GLN A 1 825  ? 124.250 123.756 98.060  1.00 20.36  ? 843  GLN A N     1 
ATOM   4684  C  CA    . GLN A 1 825  ? 123.451 124.412 97.028  1.00 20.36  ? 843  GLN A CA    1 
ATOM   4685  C  C     . GLN A 1 825  ? 124.387 125.152 96.076  1.00 20.36  ? 843  GLN A C     1 
ATOM   4686  O  O     . GLN A 1 825  ? 124.467 126.381 96.041  1.00 20.36  ? 843  GLN A O     1 
ATOM   4687  C  CB    . GLN A 1 825  ? 122.426 125.339 97.662  1.00 20.36  ? 843  GLN A CB    1 
ATOM   4688  C  CG    . GLN A 1 825  ? 121.428 124.621 98.546  1.00 20.36  ? 843  GLN A CG    1 
ATOM   4689  C  CD    . GLN A 1 825  ? 120.592 125.579 99.358  1.00 20.36  ? 843  GLN A CD    1 
ATOM   4690  O  OE1   . GLN A 1 825  ? 120.747 126.794 99.252  1.00 20.36  ? 843  GLN A OE1   1 
ATOM   4691  N  NE2   . GLN A 1 825  ? 119.702 125.039 100.180 1.00 20.36  ? 843  GLN A NE2   1 
ATOM   4692  N  N     . VAL A 1 826  ? 125.109 124.358 95.292  1.00 19.80  ? 844  VAL A N     1 
ATOM   4693  C  CA    . VAL A 1 826  ? 126.161 124.848 94.413  1.00 19.80  ? 844  VAL A CA    1 
ATOM   4694  C  C     . VAL A 1 826  ? 125.669 124.766 92.976  1.00 19.80  ? 844  VAL A C     1 
ATOM   4695  O  O     . VAL A 1 826  ? 125.109 123.745 92.557  1.00 19.80  ? 844  VAL A O     1 
ATOM   4696  C  CB    . VAL A 1 826  ? 127.467 124.056 94.606  1.00 19.80  ? 844  VAL A CB    1 
ATOM   4697  C  CG1   . VAL A 1 826  ? 127.225 122.562 94.450  1.00 19.80  ? 844  VAL A CG1   1 
ATOM   4698  C  CG2   . VAL A 1 826  ? 128.530 124.539 93.640  1.00 19.80  ? 844  VAL A CG2   1 
ATOM   4699  N  N     . VAL A 1 827  ? 125.850 125.851 92.234  1.00 21.06  ? 845  VAL A N     1 
ATOM   4700  C  CA    . VAL A 1 827  ? 125.541 125.861 90.811  1.00 21.06  ? 845  VAL A CA    1 
ATOM   4701  C  C     . VAL A 1 827  ? 126.718 125.259 90.060  1.00 21.06  ? 845  VAL A C     1 
ATOM   4702  O  O     . VAL A 1 827  ? 127.869 125.667 90.255  1.00 21.06  ? 845  VAL A O     1 
ATOM   4703  C  CB    . VAL A 1 827  ? 125.233 127.287 90.331  1.00 21.06  ? 845  VAL A CB    1 
ATOM   4704  C  CG1   . VAL A 1 827  ? 123.818 127.674 90.718  1.00 21.06  ? 845  VAL A CG1   1 
ATOM   4705  C  CG2   . VAL A 1 827  ? 126.225 128.267 90.927  1.00 21.06  ? 845  VAL A CG2   1 
ATOM   4706  N  N     . THR A 1 828  ? 126.434 124.271 89.211  1.00 20.33  ? 846  THR A N     1 
ATOM   4707  C  CA    . THR A 1 828  ? 127.506 123.539 88.544  1.00 20.33  ? 846  THR A CA    1 
ATOM   4708  C  C     . THR A 1 828  ? 128.367 124.466 87.699  1.00 20.33  ? 846  THR A C     1 
ATOM   4709  O  O     . THR A 1 828  ? 129.594 124.328 87.668  1.00 20.33  ? 846  THR A O     1 
ATOM   4710  C  CB    . THR A 1 828  ? 126.920 122.425 87.682  1.00 20.33  ? 846  THR A CB    1 
ATOM   4711  O  OG1   . THR A 1 828  ? 126.215 122.999 86.576  1.00 20.33  ? 846  THR A OG1   1 
ATOM   4712  C  CG2   . THR A 1 828  ? 125.958 121.589 88.496  1.00 20.33  ? 846  THR A CG2   1 
ATOM   4713  N  N     . ALA A 1 829  ? 127.746 125.417 87.009  1.00 21.14  ? 847  ALA A N     1 
ATOM   4714  C  CA    . ALA A 1 829  ? 128.455 126.400 86.195  1.00 21.14  ? 847  ALA A CA    1 
ATOM   4715  C  C     . ALA A 1 829  ? 128.017 127.780 86.670  1.00 21.14  ? 847  ALA A C     1 
ATOM   4716  O  O     . ALA A 1 829  ? 127.082 128.368 86.124  1.00 21.14  ? 847  ALA A O     1 
ATOM   4717  C  CB    . ALA A 1 829  ? 128.171 126.196 84.713  1.00 21.14  ? 847  ALA A CB    1 
ATOM   4718  N  N     . GLY A 1 830  ? 128.693 128.294 87.690  1.00 22.36  ? 848  GLY A N     1 
ATOM   4719  C  CA    . GLY A 1 830  ? 128.359 129.574 88.272  1.00 22.36  ? 848  GLY A CA    1 
ATOM   4720  C  C     . GLY A 1 830  ? 129.162 130.748 87.765  1.00 22.36  ? 848  GLY A C     1 
ATOM   4721  O  O     . GLY A 1 830  ? 129.025 131.850 88.307  1.00 22.36  ? 848  GLY A O     1 
ATOM   4722  N  N     . THR A 1 831  ? 129.992 130.556 86.743  1.00 25.60  ? 849  THR A N     1 
ATOM   4723  C  CA    . THR A 1 831  ? 130.789 131.630 86.167  1.00 25.60  ? 849  THR A CA    1 
ATOM   4724  C  C     . THR A 1 831  ? 130.865 131.426 84.661  1.00 25.60  ? 849  THR A C     1 
ATOM   4725  O  O     . THR A 1 831  ? 130.389 130.421 84.124  1.00 25.60  ? 849  THR A O     1 
ATOM   4726  C  CB    . THR A 1 831  ? 132.201 131.677 86.771  1.00 25.60  ? 849  THR A CB    1 
ATOM   4727  O  OG1   . THR A 1 831  ? 132.791 130.372 86.718  1.00 25.60  ? 849  THR A OG1   1 
ATOM   4728  C  CG2   . THR A 1 831  ? 132.173 132.163 88.211  1.00 25.60  ? 849  THR A CG2   1 
ATOM   4729  N  N     . ILE A 1 832  ? 131.475 132.394 83.972  1.00 30.75  ? 850  ILE A N     1 
ATOM   4730  C  CA    . ILE A 1 832  ? 131.786 132.210 82.557  1.00 30.75  ? 850  ILE A CA    1 
ATOM   4731  C  C     . ILE A 1 832  ? 132.724 131.028 82.377  1.00 30.75  ? 850  ILE A C     1 
ATOM   4732  O  O     . ILE A 1 832  ? 132.738 130.385 81.320  1.00 30.75  ? 850  ILE A O     1 
ATOM   4733  C  CB    . ILE A 1 832  ? 132.391 133.497 81.967  1.00 30.75  ? 850  ILE A CB    1 
ATOM   4734  C  CG1   . ILE A 1 832  ? 133.602 133.939 82.788  1.00 30.75  ? 850  ILE A CG1   1 
ATOM   4735  C  CG2   . ILE A 1 832  ? 131.348 134.594 81.904  1.00 30.75  ? 850  ILE A CG2   1 
ATOM   4736  C  CD1   . ILE A 1 832  ? 134.364 135.092 82.186  1.00 30.75  ? 850  ILE A CD1   1 
ATOM   4737  N  N     . THR A 1 833  ? 133.525 130.730 83.401  1.00 26.39  ? 851  THR A N     1 
ATOM   4738  C  CA    . THR A 1 833  ? 134.436 129.594 83.363  1.00 26.39  ? 851  THR A CA    1 
ATOM   4739  C  C     . THR A 1 833  ? 133.692 128.267 83.296  1.00 26.39  ? 851  THR A C     1 
ATOM   4740  O  O     . THR A 1 833  ? 134.180 127.323 82.663  1.00 26.39  ? 851  THR A O     1 
ATOM   4741  C  CB    . THR A 1 833  ? 135.332 129.636 84.600  1.00 26.39  ? 851  THR A CB    1 
ATOM   4742  O  OG1   . THR A 1 833  ? 136.348 130.630 84.422  1.00 26.39  ? 851  THR A OG1   1 
ATOM   4743  C  CG2   . THR A 1 833  ? 135.966 128.284 84.863  1.00 26.39  ? 851  THR A CG2   1 
ATOM   4744  N  N     . ARG A 1 834  ? 132.494 128.205 83.879  1.00 25.11  ? 852  ARG A N     1 
ATOM   4745  C  CA    . ARG A 1 834  ? 131.750 127.003 84.275  1.00 25.11  ? 852  ARG A CA    1 
ATOM   4746  C  C     . ARG A 1 834  ? 132.279 126.488 85.605  1.00 25.11  ? 852  ARG A C     1 
ATOM   4747  O  O     . ARG A 1 834  ? 131.965 125.359 86.002  1.00 25.11  ? 852  ARG A O     1 
ATOM   4748  C  CB    . ARG A 1 834  ? 131.771 125.880 83.231  1.00 25.11  ? 852  ARG A CB    1 
ATOM   4749  C  CG    . ARG A 1 834  ? 130.771 126.076 82.105  1.00 25.11  ? 852  ARG A CG    1 
ATOM   4750  C  CD    . ARG A 1 834  ? 131.292 125.574 80.766  1.00 25.11  ? 852  ARG A CD    1 
ATOM   4751  N  NE    . ARG A 1 834  ? 131.745 124.191 80.815  1.00 25.11  ? 852  ARG A NE    1 
ATOM   4752  C  CZ    . ARG A 1 834  ? 133.000 123.810 80.622  1.00 25.11  ? 852  ARG A CZ    1 
ATOM   4753  N  NH1   . ARG A 1 834  ? 133.954 124.686 80.355  1.00 25.11  ? 852  ARG A NH1   1 
ATOM   4754  N  NH2   . ARG A 1 834  ? 133.304 122.517 80.690  1.00 25.11  ? 852  ARG A NH2   1 
ATOM   4755  N  N     . ARG A 1 835  ? 133.075 127.292 86.305  1.00 24.37  ? 853  ARG A N     1 
ATOM   4756  C  CA    . ARG A 1 835  ? 133.510 126.963 87.654  1.00 24.37  ? 853  ARG A CA    1 
ATOM   4757  C  C     . ARG A 1 835  ? 132.326 127.006 88.609  1.00 24.37  ? 853  ARG A C     1 
ATOM   4758  O  O     . ARG A 1 835  ? 131.559 127.974 88.618  1.00 24.37  ? 853  ARG A O     1 
ATOM   4759  C  CB    . ARG A 1 835  ? 134.584 127.953 88.098  1.00 24.37  ? 853  ARG A CB    1 
ATOM   4760  C  CG    . ARG A 1 835  ? 135.322 127.597 89.364  1.00 24.37  ? 853  ARG A CG    1 
ATOM   4761  C  CD    . ARG A 1 835  ? 136.370 128.657 89.648  1.00 24.37  ? 853  ARG A CD    1 
ATOM   4762  N  NE    . ARG A 1 835  ? 137.214 128.327 90.789  1.00 24.37  ? 853  ARG A NE    1 
ATOM   4763  C  CZ    . ARG A 1 835  ? 138.205 129.091 91.226  1.00 24.37  ? 853  ARG A CZ    1 
ATOM   4764  N  NH1   . ARG A 1 835  ? 138.497 130.243 90.646  1.00 24.37  ? 853  ARG A NH1   1 
ATOM   4765  N  NH2   . ARG A 1 835  ? 138.922 128.689 92.271  1.00 24.37  ? 853  ARG A NH2   1 
ATOM   4766  N  N     . ALA A 1 836  ? 132.174 125.959 89.412  1.00 19.33  ? 854  ALA A N     1 
ATOM   4767  C  CA    . ALA A 1 836  ? 131.085 125.919 90.376  1.00 19.33  ? 854  ALA A CA    1 
ATOM   4768  C  C     . ALA A 1 836  ? 131.276 126.992 91.441  1.00 19.33  ? 854  ALA A C     1 
ATOM   4769  O  O     . ALA A 1 836  ? 132.400 127.326 91.826  1.00 19.33  ? 854  ALA A O     1 
ATOM   4770  C  CB    . ALA A 1 836  ? 130.996 124.541 91.026  1.00 19.33  ? 854  ALA A CB    1 
ATOM   4771  N  N     . VAL A 1 837  ? 130.161 127.540 91.916  1.00 19.97  ? 855  VAL A N     1 
ATOM   4772  C  CA    . VAL A 1 837  ? 130.173 128.657 92.852  1.00 19.97  ? 855  VAL A CA    1 
ATOM   4773  C  C     . VAL A 1 837  ? 129.302 128.310 94.049  1.00 19.97  ? 855  VAL A C     1 
ATOM   4774  O  O     . VAL A 1 837  ? 128.160 127.867 93.885  1.00 19.97  ? 855  VAL A O     1 
ATOM   4775  C  CB    . VAL A 1 837  ? 129.682 129.959 92.189  1.00 19.97  ? 855  VAL A CB    1 
ATOM   4776  C  CG1   . VAL A 1 837  ? 129.506 131.050 93.228  1.00 19.97  ? 855  VAL A CG1   1 
ATOM   4777  C  CG2   . VAL A 1 837  ? 130.659 130.401 91.117  1.00 19.97  ? 855  VAL A CG2   1 
ATOM   4778  N  N     . GLU A 1 838  ? 129.850 128.501 95.251  1.00 22.75  ? 856  GLU A N     1 
ATOM   4779  C  CA    . GLU A 1 838  ? 129.096 128.404 96.491  1.00 22.75  ? 856  GLU A CA    1 
ATOM   4780  C  C     . GLU A 1 838  ? 129.851 129.195 97.540  1.00 22.75  ? 856  GLU A C     1 
ATOM   4781  O  O     . GLU A 1 838  ? 131.083 129.088 97.602  1.00 22.75  ? 856  GLU A O     1 
ATOM   4782  C  CB    . GLU A 1 838  ? 128.914 126.954 96.945  1.00 22.75  ? 856  GLU A CB    1 
ATOM   4783  C  CG    . GLU A 1 838  ? 128.061 126.813 98.186  1.00 22.75  ? 856  GLU A CG    1 
ATOM   4784  C  CD    . GLU A 1 838  ? 127.608 125.399 98.408  1.00 22.75  ? 856  GLU A CD    1 
ATOM   4785  O  OE1   . GLU A 1 838  ? 128.125 124.508 97.708  1.00 22.75  ? 856  GLU A OE1   1 
ATOM   4786  O  OE2   . GLU A 1 838  ? 126.735 125.179 99.271  1.00 22.75  ? 856  GLU A OE2   1 
ATOM   4787  N  N     . PRO A 1 839  ? 129.171 129.994 98.367  1.00 23.73  ? 857  PRO A N     1 
ATOM   4788  C  CA    . PRO A 1 839  ? 129.919 130.886 99.264  1.00 23.73  ? 857  PRO A CA    1 
ATOM   4789  C  C     . PRO A 1 839  ? 130.520 130.187 100.468 1.00 23.73  ? 857  PRO A C     1 
ATOM   4790  O  O     . PRO A 1 839  ? 131.597 130.587 100.924 1.00 23.73  ? 857  PRO A O     1 
ATOM   4791  C  CB    . PRO A 1 839  ? 128.863 131.921 99.671  1.00 23.73  ? 857  PRO A CB    1 
ATOM   4792  C  CG    . PRO A 1 839  ? 127.576 131.189 99.572  1.00 23.73  ? 857  PRO A CG    1 
ATOM   4793  C  CD    . PRO A 1 839  ? 127.723 130.257 98.406  1.00 23.73  ? 857  PRO A CD    1 
ATOM   4794  N  N     . THR A 1 840  ? 129.841 129.192 101.019 1.00 21.98  ? 858  THR A N     1 
ATOM   4795  C  CA    . THR A 1 840  ? 130.323 128.573 102.256 1.00 21.98  ? 858  THR A CA    1 
ATOM   4796  C  C     . THR A 1 840  ? 131.226 127.377 102.063 1.00 21.98  ? 858  THR A C     1 
ATOM   4797  O  O     . THR A 1 840  ? 132.390 127.414 102.449 1.00 21.98  ? 858  THR A O     1 
ATOM   4798  C  CB    . THR A 1 840  ? 129.146 128.105 103.142 1.00 21.98  ? 858  THR A CB    1 
ATOM   4799  O  OG1   . THR A 1 840  ? 128.558 126.923 102.591 1.00 21.98  ? 858  THR A OG1   1 
ATOM   4800  C  CG2   . THR A 1 840  ? 128.094 129.186 103.228 1.00 21.98  ? 858  THR A CG2   1 
ATOM   4801  N  N     . TRP A 1 841  ? 130.714 126.319 101.462 1.00 21.22  ? 859  TRP A N     1 
ATOM   4802  C  CA    . TRP A 1 841  ? 131.481 125.082 101.355 1.00 21.22  ? 859  TRP A CA    1 
ATOM   4803  C  C     . TRP A 1 841  ? 132.690 125.248 100.445 1.00 21.22  ? 859  TRP A C     1 
ATOM   4804  O  O     . TRP A 1 841  ? 133.816 124.908 100.824 1.00 21.22  ? 859  TRP A O     1 
ATOM   4805  C  CB    . TRP A 1 841  ? 130.586 123.953 100.854 1.00 21.22  ? 859  TRP A CB    1 
ATOM   4806  C  CG    . TRP A 1 841  ? 129.472 123.609 101.779 1.00 21.22  ? 859  TRP A CG    1 
ATOM   4807  C  CD1   . TRP A 1 841  ? 128.140 123.748 101.540 1.00 21.22  ? 859  TRP A CD1   1 
ATOM   4808  C  CD2   . TRP A 1 841  ? 129.588 123.065 103.098 1.00 21.22  ? 859  TRP A CD2   1 
ATOM   4809  N  NE1   . TRP A 1 841  ? 127.415 123.321 102.626 1.00 21.22  ? 859  TRP A NE1   1 
ATOM   4810  C  CE2   . TRP A 1 841  ? 128.283 122.897 103.597 1.00 21.22  ? 859  TRP A CE2   1 
ATOM   4811  C  CE3   . TRP A 1 841  ? 130.669 122.703 103.906 1.00 21.22  ? 859  TRP A CE3   1 
ATOM   4812  C  CZ2   . TRP A 1 841  ? 128.029 122.385 104.866 1.00 21.22  ? 859  TRP A CZ2   1 
ATOM   4813  C  CZ3   . TRP A 1 841  ? 130.415 122.192 105.165 1.00 21.22  ? 859  TRP A CZ3   1 
ATOM   4814  C  CH2   . TRP A 1 841  ? 129.106 122.038 105.632 1.00 21.22  ? 859  TRP A CH2   1 
ATOM   4815  N  N     . LEU A 1 842  ? 132.480 125.773 99.239  1.00 23.04  ? 860  LEU A N     1 
ATOM   4816  C  CA    . LEU A 1 842  ? 133.552 125.889 98.248  1.00 23.04  ? 860  LEU A CA    1 
ATOM   4817  C  C     . LEU A 1 842  ? 134.389 127.133 98.544  1.00 23.04  ? 860  LEU A C     1 
ATOM   4818  O  O     . LEU A 1 842  ? 134.328 128.154 97.857  1.00 23.04  ? 860  LEU A O     1 
ATOM   4819  C  CB    . LEU A 1 842  ? 132.981 125.919 96.837  1.00 23.04  ? 860  LEU A CB    1 
ATOM   4820  C  CG    . LEU A 1 842  ? 132.702 124.572 96.169  1.00 23.04  ? 860  LEU A CG    1 
ATOM   4821  C  CD1   . LEU A 1 842  ? 131.544 123.844 96.831  1.00 23.04  ? 860  LEU A CD1   1 
ATOM   4822  C  CD2   . LEU A 1 842  ? 132.445 124.756 94.684  1.00 23.04  ? 860  LEU A CD2   1 
ATOM   4823  N  N     . THR A 1 843  ? 135.199 126.999 99.578  1.00 30.51  ? 861  THR A N     1 
ATOM   4824  C  CA    . THR A 1 843  ? 136.086 128.078 99.939  1.00 30.51  ? 861  THR A CA    1 
ATOM   4825  C  C     . THR A 1 843  ? 137.462 127.524 100.242 1.00 30.51  ? 861  THR A C     1 
ATOM   4826  O  O     . THR A 1 843  ? 137.605 126.332 100.493 1.00 30.51  ? 861  THR A O     1 
ATOM   4827  C  CB    . THR A 1 843  ? 135.582 128.803 101.180 1.00 30.51  ? 861  THR A CB    1 
ATOM   4828  O  OG1   . THR A 1 843  ? 135.169 127.836 102.155 1.00 30.51  ? 861  THR A OG1   1 
ATOM   4829  C  CG2   . THR A 1 843  ? 134.402 129.682 100.828 1.00 30.51  ? 861  THR A CG2   1 
ATOM   4830  N  N     . ALA A 1 844  ? 138.478 128.368 100.214 1.00 40.90  ? 862  ALA A N     1 
ATOM   4831  C  CA    . ALA A 1 844  ? 139.848 127.974 100.509 1.00 40.90  ? 862  ALA A CA    1 
ATOM   4832  C  C     . ALA A 1 844  ? 140.182 128.043 101.992 1.00 40.90  ? 862  ALA A C     1 
ATOM   4833  O  O     . ALA A 1 844  ? 141.289 127.656 102.380 1.00 40.90  ? 862  ALA A O     1 
ATOM   4834  C  CB    . ALA A 1 844  ? 140.830 128.849 99.723  1.00 40.90  ? 862  ALA A CB    1 
ATOM   4835  N  N     . SER A 1 845  ? 139.261 128.523 102.822 1.00 47.07  ? 863  SER A N     1 
ATOM   4836  C  CA    . SER A 1 845  ? 139.517 128.622 104.251 1.00 47.07  ? 863  SER A CA    1 
ATOM   4837  C  C     . SER A 1 845  ? 139.543 127.238 104.888 1.00 47.07  ? 863  SER A C     1 
ATOM   4838  O  O     . SER A 1 845  ? 138.714 126.377 104.580 1.00 47.07  ? 863  SER A O     1 
ATOM   4839  C  CB    . SER A 1 845  ? 138.454 129.492 104.920 1.00 47.07  ? 863  SER A CB    1 
ATOM   4840  O  OG    . SER A 1 845  ? 138.432 130.793 104.358 1.00 47.07  ? 863  SER A OG    1 
ATOM   4841  N  N     . ASN A 1 846  ? 140.505 127.031 105.783 1.00 42.30  ? 864  ASN A N     1 
ATOM   4842  C  CA    . ASN A 1 846  ? 140.679 125.773 106.490 1.00 42.30  ? 864  ASN A CA    1 
ATOM   4843  C  C     . ASN A 1 846  ? 140.787 126.048 107.984 1.00 42.30  ? 864  ASN A C     1 
ATOM   4844  O  O     . ASN A 1 846  ? 140.891 127.198 108.419 1.00 42.30  ? 864  ASN A O     1 
ATOM   4845  C  CB    . ASN A 1 846  ? 141.915 125.019 105.985 1.00 42.30  ? 864  ASN A CB    1 
ATOM   4846  C  CG    . ASN A 1 846  ? 143.063 125.948 105.653 1.00 42.30  ? 864  ASN A CG    1 
ATOM   4847  O  OD1   . ASN A 1 846  ? 143.069 127.112 106.051 1.00 42.30  ? 864  ASN A OD1   1 
ATOM   4848  N  ND2   . ASN A 1 846  ? 144.041 125.439 104.913 1.00 42.30  ? 864  ASN A ND2   1 
ATOM   4849  N  N     . ALA A 1 847  ? 140.752 124.973 108.770 1.00 33.35  ? 865  ALA A N     1 
ATOM   4850  C  CA    . ALA A 1 847  ? 140.797 125.102 110.220 1.00 33.35  ? 865  ALA A CA    1 
ATOM   4851  C  C     . ALA A 1 847  ? 142.076 125.800 110.661 1.00 33.35  ? 865  ALA A C     1 
ATOM   4852  O  O     . ALA A 1 847  ? 143.162 125.534 110.140 1.00 33.35  ? 865  ALA A O     1 
ATOM   4853  C  CB    . ALA A 1 847  ? 140.698 123.727 110.878 1.00 33.35  ? 865  ALA A CB    1 
ATOM   4854  N  N     . ARG A 1 848  ? 141.941 126.705 111.623 1.00 28.09  ? 866  ARG A N     1 
ATOM   4855  C  CA    . ARG A 1 848  ? 143.064 127.464 112.144 1.00 28.09  ? 866  ARG A CA    1 
ATOM   4856  C  C     . ARG A 1 848  ? 142.970 127.516 113.659 1.00 28.09  ? 866  ARG A C     1 
ATOM   4857  O  O     . ARG A 1 848  ? 141.873 127.410 114.219 1.00 28.09  ? 866  ARG A O     1 
ATOM   4858  C  CB    . ARG A 1 848  ? 143.092 128.893 111.579 1.00 28.09  ? 866  ARG A CB    1 
ATOM   4859  C  CG    . ARG A 1 848  ? 143.155 128.956 110.069 1.00 28.09  ? 866  ARG A CG    1 
ATOM   4860  C  CD    . ARG A 1 848  ? 143.055 130.380 109.571 1.00 28.09  ? 866  ARG A CD    1 
ATOM   4861  N  NE    . ARG A 1 848  ? 144.130 131.213 110.093 1.00 28.09  ? 866  ARG A NE    1 
ATOM   4862  C  CZ    . ARG A 1 848  ? 144.402 132.436 109.662 1.00 28.09  ? 866  ARG A CZ    1 
ATOM   4863  N  NH1   . ARG A 1 848  ? 143.700 132.999 108.693 1.00 28.09  ? 866  ARG A NH1   1 
ATOM   4864  N  NH2   . ARG A 1 848  ? 145.406 133.110 110.215 1.00 28.09  ? 866  ARG A NH2   1 
ATOM   4865  N  N     . PRO A 1 849  ? 144.101 127.674 114.350 1.00 24.79  ? 867  PRO A N     1 
ATOM   4866  C  CA    . PRO A 1 849  ? 144.064 127.867 115.803 1.00 24.79  ? 867  PRO A CA    1 
ATOM   4867  C  C     . PRO A 1 849  ? 143.669 129.269 116.234 1.00 24.79  ? 867  PRO A C     1 
ATOM   4868  O  O     . PRO A 1 849  ? 143.644 129.541 117.440 1.00 24.79  ? 867  PRO A O     1 
ATOM   4869  C  CB    . PRO A 1 849  ? 145.505 127.551 116.223 1.00 24.79  ? 867  PRO A CB    1 
ATOM   4870  C  CG    . PRO A 1 849  ? 146.317 127.928 115.036 1.00 24.79  ? 867  PRO A CG    1 
ATOM   4871  C  CD    . PRO A 1 849  ? 145.480 127.566 113.842 1.00 24.79  ? 867  PRO A CD    1 
ATOM   4872  N  N     . ASP A 1 850  ? 143.358 130.159 115.297 1.00 23.28  ? 868  ASP A N     1 
ATOM   4873  C  CA    . ASP A 1 850  ? 143.036 131.551 115.583 1.00 23.28  ? 868  ASP A CA    1 
ATOM   4874  C  C     . ASP A 1 850  ? 141.786 131.973 114.823 1.00 23.28  ? 868  ASP A C     1 
ATOM   4875  O  O     . ASP A 1 850  ? 141.741 133.028 114.188 1.00 23.28  ? 868  ASP A O     1 
ATOM   4876  C  CB    . ASP A 1 850  ? 144.218 132.449 115.226 1.00 23.28  ? 868  ASP A CB    1 
ATOM   4877  C  CG    . ASP A 1 850  ? 144.072 133.855 115.772 1.00 23.28  ? 868  ASP A CG    1 
ATOM   4878  O  OD1   . ASP A 1 850  ? 143.313 134.043 116.743 1.00 23.28  ? 868  ASP A OD1   1 
ATOM   4879  O  OD2   . ASP A 1 850  ? 144.712 134.776 115.222 1.00 23.28  ? 868  ASP A OD2   1 
ATOM   4880  N  N     . ARG A 1 851  ? 140.748 131.135 114.863 1.00 19.24  ? 869  ARG A N     1 
ATOM   4881  C  CA    . ARG A 1 851  ? 139.518 131.441 114.129 1.00 19.24  ? 869  ARG A CA    1 
ATOM   4882  C  C     . ARG A 1 851  ? 138.336 130.638 114.605 1.00 19.24  ? 869  ARG A C     1 
ATOM   4883  O  O     . ARG A 1 851  ? 138.277 129.445 114.381 1.00 19.24  ? 869  ARG A O     1 
ATOM   4884  C  CB    . ARG A 1 851  ? 139.720 131.198 112.652 1.00 19.24  ? 869  ARG A CB    1 
ATOM   4885  C  CG    . ARG A 1 851  ? 138.820 132.021 111.755 1.00 19.24  ? 869  ARG A CG    1 
ATOM   4886  C  CD    . ARG A 1 851  ? 138.916 133.491 112.111 1.00 19.24  ? 869  ARG A CD    1 
ATOM   4887  N  NE    . ARG A 1 851  ? 140.293 133.904 112.342 1.00 19.24  ? 869  ARG A NE    1 
ATOM   4888  C  CZ    . ARG A 1 851  ? 141.079 134.435 111.417 1.00 19.24  ? 869  ARG A CZ    1 
ATOM   4889  N  NH1   . ARG A 1 851  ? 140.623 134.624 110.190 1.00 19.24  ? 869  ARG A NH1   1 
ATOM   4890  N  NH2   . ARG A 1 851  ? 142.320 134.782 111.723 1.00 19.24  ? 869  ARG A NH2   1 
ATOM   4891  N  N     . VAL A 1 852  ? 137.374 131.290 115.237 1.00 17.12  ? 870  VAL A N     1 
ATOM   4892  C  CA    . VAL A 1 852  ? 136.225 130.596 115.805 1.00 17.12  ? 870  VAL A CA    1 
ATOM   4893  C  C     . VAL A 1 852  ? 135.396 129.982 114.686 1.00 17.12  ? 870  VAL A C     1 
ATOM   4894  O  O     . VAL A 1 852  ? 135.120 130.628 113.668 1.00 17.12  ? 870  VAL A O     1 
ATOM   4895  C  CB    . VAL A 1 852  ? 135.380 131.555 116.657 1.00 17.12  ? 870  VAL A CB    1 
ATOM   4896  C  CG1   . VAL A 1 852  ? 134.204 130.816 117.285 1.00 17.12  ? 870  VAL A CG1   1 
ATOM   4897  C  CG2   . VAL A 1 852  ? 136.239 132.212 117.726 1.00 17.12  ? 870  VAL A CG2   1 
ATOM   4898  N  N     . GLY A 1 853  ? 134.991 128.729 114.873 1.00 18.30  ? 871  GLY A N     1 
ATOM   4899  C  CA    . GLY A 1 853  ? 134.126 128.072 113.914 1.00 18.30  ? 871  GLY A CA    1 
ATOM   4900  C  C     . GLY A 1 853  ? 134.758 127.772 112.576 1.00 18.30  ? 871  GLY A C     1 
ATOM   4901  O  O     . GLY A 1 853  ? 134.040 127.504 111.612 1.00 18.30  ? 871  GLY A O     1 
ATOM   4902  N  N     . SER A 1 854  ? 136.086 127.797 112.490 1.00 21.44  ? 872  SER A N     1 
ATOM   4903  C  CA    . SER A 1 854  ? 136.777 127.556 111.233 1.00 21.44  ? 872  SER A CA    1 
ATOM   4904  C  C     . SER A 1 854  ? 136.952 126.077 110.924 1.00 21.44  ? 872  SER A C     1 
ATOM   4905  O  O     . SER A 1 854  ? 137.488 125.745 109.863 1.00 21.44  ? 872  SER A O     1 
ATOM   4906  C  CB    . SER A 1 854  ? 138.144 128.237 111.246 1.00 21.44  ? 872  SER A CB    1 
ATOM   4907  O  OG    . SER A 1 854  ? 138.727 128.209 109.958 1.00 21.44  ? 872  SER A OG    1 
ATOM   4908  N  N     . GLU A 1 855  ? 136.518 125.188 111.816 1.00 22.77  ? 873  GLU A N     1 
ATOM   4909  C  CA    . GLU A 1 855  ? 136.610 123.750 111.603 1.00 22.77  ? 873  GLU A CA    1 
ATOM   4910  C  C     . GLU A 1 855  ? 135.389 123.178 110.887 1.00 22.77  ? 873  GLU A C     1 
ATOM   4911  O  O     . GLU A 1 855  ? 135.115 121.979 111.012 1.00 22.77  ? 873  GLU A O     1 
ATOM   4912  C  CB    . GLU A 1 855  ? 136.824 123.031 112.938 1.00 22.77  ? 873  GLU A CB    1 
ATOM   4913  C  CG    . GLU A 1 855  ? 135.620 123.028 113.880 1.00 22.77  ? 873  GLU A CG    1 
ATOM   4914  C  CD    . GLU A 1 855  ? 135.603 124.213 114.823 1.00 22.77  ? 873  GLU A CD    1 
ATOM   4915  O  OE1   . GLU A 1 855  ? 136.422 125.132 114.635 1.00 22.77  ? 873  GLU A OE1   1 
ATOM   4916  O  OE2   . GLU A 1 855  ? 134.776 124.225 115.758 1.00 22.77  ? 873  GLU A OE2   1 
ATOM   4917  N  N     . LEU A 1 856  ? 134.655 124.000 110.128 1.00 22.49  ? 874  LEU A N     1 
ATOM   4918  C  CA    . LEU A 1 856  ? 133.385 123.546 109.565 1.00 22.49  ? 874  LEU A CA    1 
ATOM   4919  C  C     . LEU A 1 856  ? 133.583 122.385 108.600 1.00 22.49  ? 874  LEU A C     1 
ATOM   4920  O  O     . LEU A 1 856  ? 132.791 121.436 108.592 1.00 22.49  ? 874  LEU A O     1 
ATOM   4921  C  CB    . LEU A 1 856  ? 132.659 124.702 108.872 1.00 22.49  ? 874  LEU A CB    1 
ATOM   4922  C  CG    . LEU A 1 856  ? 133.179 125.255 107.544 1.00 22.49  ? 874  LEU A CG    1 
ATOM   4923  C  CD1   . LEU A 1 856  ? 132.020 125.719 106.682 1.00 22.49  ? 874  LEU A CD1   1 
ATOM   4924  C  CD2   . LEU A 1 856  ? 134.157 126.391 107.777 1.00 22.49  ? 874  LEU A CD2   1 
ATOM   4925  N  N     . LYS A 1 857  ? 134.629 122.443 107.773 1.00 23.49  ? 875  LYS A N     1 
ATOM   4926  C  CA    . LYS A 1 857  ? 134.912 121.336 106.867 1.00 23.49  ? 875  LYS A CA    1 
ATOM   4927  C  C     . LYS A 1 857  ? 135.281 120.081 107.641 1.00 23.49  ? 875  LYS A C     1 
ATOM   4928  O  O     . LYS A 1 857  ? 134.899 118.970 107.258 1.00 23.49  ? 875  LYS A O     1 
ATOM   4929  C  CB    . LYS A 1 857  ? 136.018 121.729 105.892 1.00 23.49  ? 875  LYS A CB    1 
ATOM   4930  C  CG    . LYS A 1 857  ? 135.545 122.682 104.811 1.00 23.49  ? 875  LYS A CG    1 
ATOM   4931  C  CD    . LYS A 1 857  ? 136.691 123.459 104.200 1.00 23.49  ? 875  LYS A CD    1 
ATOM   4932  C  CE    . LYS A 1 857  ? 136.171 124.518 103.246 1.00 23.49  ? 875  LYS A CE    1 
ATOM   4933  N  NZ    . LYS A 1 857  ? 137.232 125.478 102.843 1.00 23.49  ? 875  LYS A NZ    1 
ATOM   4934  N  N     . ALA A 1 858  ? 136.010 120.239 108.747 1.00 22.19  ? 876  ALA A N     1 
ATOM   4935  C  CA    . ALA A 1 858  ? 136.316 119.104 109.608 1.00 22.19  ? 876  ALA A CA    1 
ATOM   4936  C  C     . ALA A 1 858  ? 135.065 118.496 110.225 1.00 22.19  ? 876  ALA A C     1 
ATOM   4937  O  O     . ALA A 1 858  ? 135.125 117.373 110.735 1.00 22.19  ? 876  ALA A O     1 
ATOM   4938  C  CB    . ALA A 1 858  ? 137.286 119.526 110.707 1.00 22.19  ? 876  ALA A CB    1 
ATOM   4939  N  N     . MET A 1 859  ? 133.940 119.207 110.200 1.00 22.53  ? 877  MET A N     1 
ATOM   4940  C  CA    . MET A 1 859  ? 132.685 118.659 110.694 1.00 22.53  ? 877  MET A CA    1 
ATOM   4941  C  C     . MET A 1 859  ? 131.976 117.810 109.654 1.00 22.53  ? 877  MET A C     1 
ATOM   4942  O  O     . MET A 1 859  ? 130.875 117.320 109.922 1.00 22.53  ? 877  MET A O     1 
ATOM   4943  C  CB    . MET A 1 859  ? 131.754 119.780 111.161 1.00 22.53  ? 877  MET A CB    1 
ATOM   4944  C  CG    . MET A 1 859  ? 132.415 120.818 112.053 1.00 22.53  ? 877  MET A CG    1 
ATOM   4945  S  SD    . MET A 1 859  ? 133.369 120.114 113.409 1.00 22.53  ? 877  MET A SD    1 
ATOM   4946  C  CE    . MET A 1 859  ? 132.111 119.172 114.263 1.00 22.53  ? 877  MET A CE    1 
ATOM   4947  N  N     . VAL A 1 860  ? 132.573 117.643 108.479 1.00 19.06  ? 878  VAL A N     1 
ATOM   4948  C  CA    . VAL A 1 860  ? 132.065 116.692 107.479 1.00 19.06  ? 878  VAL A CA    1 
ATOM   4949  C  C     . VAL A 1 860  ? 132.731 115.362 107.803 1.00 19.06  ? 878  VAL A C     1 
ATOM   4950  O  O     . VAL A 1 860  ? 133.758 114.977 107.242 1.00 19.06  ? 878  VAL A O     1 
ATOM   4951  C  CB    . VAL A 1 860  ? 132.336 117.153 106.047 1.00 19.06  ? 878  VAL A CB    1 
ATOM   4952  C  CG1   . VAL A 1 860  ? 131.737 116.167 105.064 1.00 19.06  ? 878  VAL A CG1   1 
ATOM   4953  C  CG2   . VAL A 1 860  ? 131.785 118.550 105.823 1.00 19.06  ? 878  VAL A CG2   1 
ATOM   4954  N  N     . GLN A 1 861  ? 132.134 114.645 108.742 1.00 20.58  ? 879  GLN A N     1 
ATOM   4955  C  CA    . GLN A 1 861  ? 132.696 113.405 109.254 1.00 20.58  ? 879  GLN A CA    1 
ATOM   4956  C  C     . GLN A 1 861  ? 131.940 112.233 108.646 1.00 20.58  ? 879  GLN A C     1 
ATOM   4957  O  O     . GLN A 1 861  ? 130.728 112.102 108.848 1.00 20.58  ? 879  GLN A O     1 
ATOM   4958  C  CB    . GLN A 1 861  ? 132.629 113.380 110.779 1.00 20.58  ? 879  GLN A CB    1 
ATOM   4959  C  CG    . GLN A 1 861  ? 133.574 114.371 111.441 1.00 20.58  ? 879  GLN A CG    1 
ATOM   4960  C  CD    . GLN A 1 861  ? 133.012 114.946 112.724 1.00 20.58  ? 879  GLN A CD    1 
ATOM   4961  O  OE1   . GLN A 1 861  ? 131.935 114.556 113.169 1.00 20.58  ? 879  GLN A OE1   1 
ATOM   4962  N  NE2   . GLN A 1 861  ? 133.737 115.885 113.321 1.00 20.58  ? 879  GLN A NE2   1 
ATOM   4963  N  N     . ALA A 1 862  ? 132.655 111.396 107.905 1.00 15.99  ? 880  ALA A N     1 
ATOM   4964  C  CA    . ALA A 1 862  ? 132.030 110.259 107.253 1.00 15.99  ? 880  ALA A CA    1 
ATOM   4965  C  C     . ALA A 1 862  ? 131.388 109.351 108.295 1.00 15.99  ? 880  ALA A C     1 
ATOM   4966  O  O     . ALA A 1 862  ? 131.931 109.186 109.393 1.00 15.99  ? 880  ALA A O     1 
ATOM   4967  C  CB    . ALA A 1 862  ? 133.058 109.477 106.437 1.00 15.99  ? 880  ALA A CB    1 
ATOM   4968  N  N     . PRO A 1 863  ? 130.237 108.760 107.996 1.00 21.54  ? 881  PRO A N     1 
ATOM   4969  C  CA    . PRO A 1 863  ? 129.569 107.891 108.969 1.00 21.54  ? 881  PRO A CA    1 
ATOM   4970  C  C     . PRO A 1 863  ? 130.428 106.685 109.301 1.00 21.54  ? 881  PRO A C     1 
ATOM   4971  O  O     . PRO A 1 863  ? 131.358 106.353 108.551 1.00 21.54  ? 881  PRO A O     1 
ATOM   4972  C  CB    . PRO A 1 863  ? 128.274 107.481 108.247 1.00 21.54  ? 881  PRO A CB    1 
ATOM   4973  C  CG    . PRO A 1 863  ? 128.541 107.718 106.808 1.00 21.54  ? 881  PRO A CG    1 
ATOM   4974  C  CD    . PRO A 1 863  ? 129.468 108.887 106.748 1.00 21.54  ? 881  PRO A CD    1 
ATOM   4975  N  N     . PRO A 1 864  ? 130.160 106.013 110.420 1.00 32.84  ? 882  PRO A N     1 
ATOM   4976  C  CA    . PRO A 1 864  ? 130.968 104.844 110.788 1.00 32.84  ? 882  PRO A CA    1 
ATOM   4977  C  C     . PRO A 1 864  ? 130.924 103.775 109.707 1.00 32.84  ? 882  PRO A C     1 
ATOM   4978  O  O     . PRO A 1 864  ? 129.861 103.253 109.364 1.00 32.84  ? 882  PRO A O     1 
ATOM   4979  C  CB    . PRO A 1 864  ? 130.321 104.360 112.091 1.00 32.84  ? 882  PRO A CB    1 
ATOM   4980  C  CG    . PRO A 1 864  ? 128.955 104.955 112.089 1.00 32.84  ? 882  PRO A CG    1 
ATOM   4981  C  CD    . PRO A 1 864  ? 129.101 106.274 111.407 1.00 32.84  ? 882  PRO A CD    1 
ATOM   4982  N  N     . GLY A 1 865  ? 132.098 103.450 109.175 1.00 29.76  ? 883  GLY A N     1 
ATOM   4983  C  CA    . GLY A 1 865  ? 132.233 102.500 108.092 1.00 29.76  ? 883  GLY A CA    1 
ATOM   4984  C  C     . GLY A 1 865  ? 132.653 103.114 106.778 1.00 29.76  ? 883  GLY A C     1 
ATOM   4985  O  O     . GLY A 1 865  ? 132.966 102.371 105.840 1.00 29.76  ? 883  GLY A O     1 
ATOM   4986  N  N     . TYR A 1 866  ? 132.680 104.439 106.678 1.00 22.06  ? 884  TYR A N     1 
ATOM   4987  C  CA    . TYR A 1 866  ? 133.040 105.126 105.449 1.00 22.06  ? 884  TYR A CA    1 
ATOM   4988  C  C     . TYR A 1 866  ? 134.301 105.948 105.653 1.00 22.06  ? 884  TYR A C     1 
ATOM   4989  O  O     . TYR A 1 866  ? 134.551 106.477 106.737 1.00 22.06  ? 884  TYR A O     1 
ATOM   4990  C  CB    . TYR A 1 866  ? 131.920 106.045 104.970 1.00 22.06  ? 884  TYR A CB    1 
ATOM   4991  C  CG    . TYR A 1 866  ? 130.751 105.328 104.356 1.00 22.06  ? 884  TYR A CG    1 
ATOM   4992  C  CD1   . TYR A 1 866  ? 129.730 104.832 105.145 1.00 22.06  ? 884  TYR A CD1   1 
ATOM   4993  C  CD2   . TYR A 1 866  ? 130.664 105.155 102.986 1.00 22.06  ? 884  TYR A CD2   1 
ATOM   4994  C  CE1   . TYR A 1 866  ? 128.658 104.182 104.589 1.00 22.06  ? 884  TYR A CE1   1 
ATOM   4995  C  CE2   . TYR A 1 866  ? 129.594 104.503 102.420 1.00 22.06  ? 884  TYR A CE2   1 
ATOM   4996  C  CZ    . TYR A 1 866  ? 128.593 104.019 103.227 1.00 22.06  ? 884  TYR A CZ    1 
ATOM   4997  O  OH    . TYR A 1 866  ? 127.518 103.368 102.672 1.00 22.06  ? 884  TYR A OH    1 
ATOM   4998  N  N     . THR A 1 867  ? 135.086 106.061 104.589 1.00 19.13  ? 885  THR A N     1 
ATOM   4999  C  CA    . THR A 1 867  ? 136.324 106.824 104.608 1.00 19.13  ? 885  THR A CA    1 
ATOM   5000  C  C     . THR A 1 867  ? 136.279 107.854 103.494 1.00 19.13  ? 885  THR A C     1 
ATOM   5001  O  O     . THR A 1 867  ? 135.985 107.515 102.346 1.00 19.13  ? 885  THR A O     1 
ATOM   5002  C  CB    . THR A 1 867  ? 137.541 105.911 104.432 1.00 19.13  ? 885  THR A CB    1 
ATOM   5003  O  OG1   . THR A 1 867  ? 137.421 105.193 103.199 1.00 19.13  ? 885  THR A OG1   1 
ATOM   5004  C  CG2   . THR A 1 867  ? 137.631 104.917 105.574 1.00 19.13  ? 885  THR A CG2   1 
ATOM   5005  N  N     . LEU A 1 868  ? 136.578 109.107 103.831 1.00 18.55  ? 886  LEU A N     1 
ATOM   5006  C  CA    . LEU A 1 868  ? 136.571 110.189 102.847 1.00 18.55  ? 886  LEU A CA    1 
ATOM   5007  C  C     . LEU A 1 868  ? 137.863 110.133 102.031 1.00 18.55  ? 886  LEU A C     1 
ATOM   5008  O  O     . LEU A 1 868  ? 138.751 110.980 102.135 1.00 18.55  ? 886  LEU A O     1 
ATOM   5009  C  CB    . LEU A 1 868  ? 136.391 111.537 103.530 1.00 18.55  ? 886  LEU A CB    1 
ATOM   5010  C  CG    . LEU A 1 868  ? 135.010 111.797 104.136 1.00 18.55  ? 886  LEU A CG    1 
ATOM   5011  C  CD1   . LEU A 1 868  ? 135.020 113.041 105.002 1.00 18.55  ? 886  LEU A CD1   1 
ATOM   5012  C  CD2   . LEU A 1 868  ? 133.970 111.923 103.041 1.00 18.55  ? 886  LEU A CD2   1 
ATOM   5013  N  N     . VAL A 1 869  ? 137.952 109.093 101.204 1.00 17.70  ? 887  VAL A N     1 
ATOM   5014  C  CA    . VAL A 1 869  ? 139.093 108.940 100.312 1.00 17.70  ? 887  VAL A CA    1 
ATOM   5015  C  C     . VAL A 1 869  ? 139.118 110.109 99.342  1.00 17.70  ? 887  VAL A C     1 
ATOM   5016  O  O     . VAL A 1 869  ? 138.164 110.329 98.586  1.00 17.70  ? 887  VAL A O     1 
ATOM   5017  C  CB    . VAL A 1 869  ? 139.019 107.604 99.573  1.00 17.70  ? 887  VAL A CB    1 
ATOM   5018  C  CG1   . VAL A 1 869  ? 140.265 107.391 98.751  1.00 17.70  ? 887  VAL A CG1   1 
ATOM   5019  C  CG2   . VAL A 1 869  ? 138.824 106.473 100.561 1.00 17.70  ? 887  VAL A CG2   1 
ATOM   5020  N  N     . GLY A 1 870  ? 140.213 110.865 99.352  1.00 16.92  ? 888  GLY A N     1 
ATOM   5021  C  CA    . GLY A 1 870  ? 140.329 112.019 98.486  1.00 16.92  ? 888  GLY A CA    1 
ATOM   5022  C  C     . GLY A 1 870  ? 141.774 112.276 98.131  1.00 16.92  ? 888  GLY A C     1 
ATOM   5023  O  O     . GLY A 1 870  ? 142.693 111.723 98.736  1.00 16.92  ? 888  GLY A O     1 
ATOM   5024  N  N     . ALA A 1 871  ? 141.968 113.137 97.133  1.00 17.94  ? 889  ALA A N     1 
ATOM   5025  C  CA    . ALA A 1 871  ? 143.318 113.429 96.660  1.00 17.94  ? 889  ALA A CA    1 
ATOM   5026  C  C     . ALA A 1 871  ? 143.319 114.823 96.035  1.00 17.94  ? 889  ALA A C     1 
ATOM   5027  O  O     . ALA A 1 871  ? 142.851 114.993 94.907  1.00 17.94  ? 889  ALA A O     1 
ATOM   5028  C  CB    . ALA A 1 871  ? 143.784 112.376 95.670  1.00 17.94  ? 889  ALA A CB    1 
ATOM   5029  N  N     . ASP A 1 872  ? 143.841 115.799 96.771  1.00 25.37  ? 890  ASP A N     1 
ATOM   5030  C  CA    . ASP A 1 872  ? 144.076 117.112 96.191  1.00 25.37  ? 890  ASP A CA    1 
ATOM   5031  C  C     . ASP A 1 872  ? 144.988 116.966 94.984  1.00 25.37  ? 890  ASP A C     1 
ATOM   5032  O  O     . ASP A 1 872  ? 146.036 116.319 95.059  1.00 25.37  ? 890  ASP A O     1 
ATOM   5033  C  CB    . ASP A 1 872  ? 144.700 118.045 97.234  1.00 25.37  ? 890  ASP A CB    1 
ATOM   5034  C  CG    . ASP A 1 872  ? 144.915 119.462 96.714  1.00 25.37  ? 890  ASP A CG    1 
ATOM   5035  O  OD1   . ASP A 1 872  ? 145.698 119.648 95.761  1.00 25.37  ? 890  ASP A OD1   1 
ATOM   5036  O  OD2   . ASP A 1 872  ? 144.302 120.398 97.269  1.00 25.37  ? 890  ASP A OD2   1 
ATOM   5037  N  N     . VAL A 1 873  ? 144.586 117.564 93.864  1.00 28.27  ? 891  VAL A N     1 
ATOM   5038  C  CA    . VAL A 1 873  ? 145.379 117.455 92.648  1.00 28.27  ? 891  VAL A CA    1 
ATOM   5039  C  C     . VAL A 1 873  ? 146.635 118.297 92.799  1.00 28.27  ? 891  VAL A C     1 
ATOM   5040  O  O     . VAL A 1 873  ? 146.568 119.496 93.099  1.00 28.27  ? 891  VAL A O     1 
ATOM   5041  C  CB    . VAL A 1 873  ? 144.557 117.879 91.423  1.00 28.27  ? 891  VAL A CB    1 
ATOM   5042  C  CG1   . VAL A 1 873  ? 145.362 117.668 90.158  1.00 28.27  ? 891  VAL A CG1   1 
ATOM   5043  C  CG2   . VAL A 1 873  ? 143.260 117.092 91.364  1.00 28.27  ? 891  VAL A CG2   1 
ATOM   5044  N  N     . ASP A 1 874  ? 147.788 117.671 92.590  1.00 31.69  ? 892  ASP A N     1 
ATOM   5045  C  CA    . ASP A 1 874  ? 149.079 118.294 92.869  1.00 31.69  ? 892  ASP A CA    1 
ATOM   5046  C  C     . ASP A 1 874  ? 149.381 119.317 91.782  1.00 31.69  ? 892  ASP A C     1 
ATOM   5047  O  O     . ASP A 1 874  ? 149.825 118.966 90.688  1.00 31.69  ? 892  ASP A O     1 
ATOM   5048  C  CB    . ASP A 1 874  ? 150.170 117.234 92.952  1.00 31.69  ? 892  ASP A CB    1 
ATOM   5049  C  CG    . ASP A 1 874  ? 149.744 116.023 93.759  1.00 31.69  ? 892  ASP A CG    1 
ATOM   5050  O  OD1   . ASP A 1 874  ? 148.899 116.175 94.666  1.00 31.69  ? 892  ASP A OD1   1 
ATOM   5051  O  OD2   . ASP A 1 874  ? 150.255 114.918 93.484  1.00 31.69  ? 892  ASP A OD2   1 
ATOM   5052  N  N     . SER A 1 875  ? 149.139 120.592 92.092  1.00 34.92  ? 893  SER A N     1 
ATOM   5053  C  CA    . SER A 1 875  ? 149.402 121.704 91.181  1.00 34.92  ? 893  SER A CA    1 
ATOM   5054  C  C     . SER A 1 875  ? 148.646 121.516 89.864  1.00 34.92  ? 893  SER A C     1 
ATOM   5055  O  O     . SER A 1 875  ? 149.231 121.362 88.791  1.00 34.92  ? 893  SER A O     1 
ATOM   5056  C  CB    . SER A 1 875  ? 150.905 121.870 90.945  1.00 34.92  ? 893  SER A CB    1 
ATOM   5057  O  OG    . SER A 1 875  ? 151.173 123.041 90.204  1.00 34.92  ? 893  SER A OG    1 
ATOM   5058  N  N     . GLN A 1 876  ? 147.317 121.521 89.977  1.00 32.13  ? 894  GLN A N     1 
ATOM   5059  C  CA    . GLN A 1 876  ? 146.458 121.187 88.845  1.00 32.13  ? 894  GLN A CA    1 
ATOM   5060  C  C     . GLN A 1 876  ? 146.594 122.200 87.716  1.00 32.13  ? 894  GLN A C     1 
ATOM   5061  O  O     . GLN A 1 876  ? 147.041 121.867 86.612  1.00 32.13  ? 894  GLN A O     1 
ATOM   5062  C  CB    . GLN A 1 876  ? 145.007 121.104 89.313  1.00 32.13  ? 894  GLN A CB    1 
ATOM   5063  C  CG    . GLN A 1 876  ? 144.018 120.807 88.213  1.00 32.13  ? 894  GLN A CG    1 
ATOM   5064  C  CD    . GLN A 1 876  ? 142.590 120.879 88.699  1.00 32.13  ? 894  GLN A CD    1 
ATOM   5065  O  OE1   . GLN A 1 876  ? 142.221 121.793 89.433  1.00 32.13  ? 894  GLN A OE1   1 
ATOM   5066  N  NE2   . GLN A 1 876  ? 141.779 119.909 88.302  1.00 32.13  ? 894  GLN A NE2   1 
ATOM   5067  N  N     . GLU A 1 877  ? 146.202 123.448 87.976  1.00 38.84  ? 895  GLU A N     1 
ATOM   5068  C  CA    . GLU A 1 877  ? 146.117 124.431 86.901  1.00 38.84  ? 895  GLU A CA    1 
ATOM   5069  C  C     . GLU A 1 877  ? 147.493 124.837 86.395  1.00 38.84  ? 895  GLU A C     1 
ATOM   5070  O  O     . GLU A 1 877  ? 147.649 125.136 85.205  1.00 38.84  ? 895  GLU A O     1 
ATOM   5071  C  CB    . GLU A 1 877  ? 145.326 125.648 87.372  1.00 38.84  ? 895  GLU A CB    1 
ATOM   5072  C  CG    . GLU A 1 877  ? 143.901 125.312 87.790  1.00 38.84  ? 895  GLU A CG    1 
ATOM   5073  C  CD    . GLU A 1 877  ? 143.094 126.537 88.155  1.00 38.84  ? 895  GLU A CD    1 
ATOM   5074  O  OE1   . GLU A 1 877  ? 143.614 127.658 87.988  1.00 38.84  ? 895  GLU A OE1   1 
ATOM   5075  O  OE2   . GLU A 1 877  ? 141.941 126.381 88.607  1.00 38.84  ? 895  GLU A OE2   1 
ATOM   5076  N  N     . LEU A 1 878  ? 148.500 124.842 87.271  1.00 41.00  ? 896  LEU A N     1 
ATOM   5077  C  CA    . LEU A 1 878  ? 149.860 125.090 86.810  1.00 41.00  ? 896  LEU A CA    1 
ATOM   5078  C  C     . LEU A 1 878  ? 150.306 124.015 85.828  1.00 41.00  ? 896  LEU A C     1 
ATOM   5079  O  O     . LEU A 1 878  ? 150.885 124.326 84.783  1.00 41.00  ? 896  LEU A O     1 
ATOM   5080  C  CB    . LEU A 1 878  ? 150.818 125.165 87.997  1.00 41.00  ? 896  LEU A CB    1 
ATOM   5081  C  CG    . LEU A 1 878  ? 150.655 126.342 88.958  1.00 41.00  ? 896  LEU A CG    1 
ATOM   5082  C  CD1   . LEU A 1 878  ? 151.678 126.257 90.074  1.00 41.00  ? 896  LEU A CD1   1 
ATOM   5083  C  CD2   . LEU A 1 878  ? 150.785 127.659 88.216  1.00 41.00  ? 896  LEU A CD2   1 
ATOM   5084  N  N     . TRP A 1 879  ? 150.014 122.747 86.128  1.00 33.87  ? 897  TRP A N     1 
ATOM   5085  C  CA    . TRP A 1 879  ? 150.349 121.673 85.197  1.00 33.87  ? 897  TRP A CA    1 
ATOM   5086  C  C     . TRP A 1 879  ? 149.549 121.783 83.906  1.00 33.87  ? 897  TRP A C     1 
ATOM   5087  O  O     . TRP A 1 879  ? 150.063 121.476 82.826  1.00 33.87  ? 897  TRP A O     1 
ATOM   5088  C  CB    . TRP A 1 879  ? 150.115 120.310 85.845  1.00 33.87  ? 897  TRP A CB    1 
ATOM   5089  C  CG    . TRP A 1 879  ? 150.399 119.169 84.917  1.00 33.87  ? 897  TRP A CG    1 
ATOM   5090  C  CD1   . TRP A 1 879  ? 151.607 118.580 84.689  1.00 33.87  ? 897  TRP A CD1   1 
ATOM   5091  C  CD2   . TRP A 1 879  ? 149.456 118.485 84.084  1.00 33.87  ? 897  TRP A CD2   1 
ATOM   5092  N  NE1   . TRP A 1 879  ? 151.475 117.569 83.768  1.00 33.87  ? 897  TRP A NE1   1 
ATOM   5093  C  CE2   . TRP A 1 879  ? 150.163 117.489 83.384  1.00 33.87  ? 897  TRP A CE2   1 
ATOM   5094  C  CE3   . TRP A 1 879  ? 148.082 118.616 83.864  1.00 33.87  ? 897  TRP A CE3   1 
ATOM   5095  C  CZ2   . TRP A 1 879  ? 149.544 116.631 82.479  1.00 33.87  ? 897  TRP A CZ2   1 
ATOM   5096  C  CZ3   . TRP A 1 879  ? 147.471 117.762 82.966  1.00 33.87  ? 897  TRP A CZ3   1 
ATOM   5097  C  CH2   . TRP A 1 879  ? 148.201 116.784 82.284  1.00 33.87  ? 897  TRP A CH2   1 
ATOM   5098  N  N     . ILE A 1 880  ? 148.283 122.192 83.999  1.00 34.50  ? 898  ILE A N     1 
ATOM   5099  C  CA    . ILE A 1 880  ? 147.455 122.333 82.803  1.00 34.50  ? 898  ILE A CA    1 
ATOM   5100  C  C     . ILE A 1 880  ? 148.041 123.389 81.874  1.00 34.50  ? 898  ILE A C     1 
ATOM   5101  O  O     . ILE A 1 880  ? 148.240 123.154 80.674  1.00 34.50  ? 898  ILE A O     1 
ATOM   5102  C  CB    . ILE A 1 880  ? 146.006 122.666 83.197  1.00 34.50  ? 898  ILE A CB    1 
ATOM   5103  C  CG1   . ILE A 1 880  ? 145.354 121.456 83.862  1.00 34.50  ? 898  ILE A CG1   1 
ATOM   5104  C  CG2   . ILE A 1 880  ? 145.209 123.118 81.990  1.00 34.50  ? 898  ILE A CG2   1 
ATOM   5105  C  CD1   . ILE A 1 880  ? 143.989 121.730 84.401  1.00 34.50  ? 898  ILE A CD1   1 
ATOM   5106  N  N     . ALA A 1 881  ? 148.342 124.565 82.422  1.00 40.80  ? 899  ALA A N     1 
ATOM   5107  C  CA    . ALA A 1 881  ? 148.953 125.614 81.616  1.00 40.80  ? 899  ALA A CA    1 
ATOM   5108  C  C     . ALA A 1 881  ? 150.328 125.188 81.113  1.00 40.80  ? 899  ALA A C     1 
ATOM   5109  O  O     . ALA A 1 881  ? 150.724 125.530 79.990  1.00 40.80  ? 899  ALA A O     1 
ATOM   5110  C  CB    . ALA A 1 881  ? 149.038 126.903 82.430  1.00 40.80  ? 899  ALA A CB    1 
ATOM   5111  N  N     . ALA A 1 882  ? 151.060 124.418 81.923  1.00 41.35  ? 900  ALA A N     1 
ATOM   5112  C  CA    . ALA A 1 882  ? 152.377 123.944 81.522  1.00 41.35  ? 900  ALA A CA    1 
ATOM   5113  C  C     . ALA A 1 882  ? 152.291 123.026 80.313  1.00 41.35  ? 900  ALA A C     1 
ATOM   5114  O  O     . ALA A 1 882  ? 153.071 123.161 79.368  1.00 41.35  ? 900  ALA A O     1 
ATOM   5115  C  CB    . ALA A 1 882  ? 153.053 123.229 82.691  1.00 41.35  ? 900  ALA A CB    1 
ATOM   5116  N  N     . VAL A 1 883  ? 151.353 122.076 80.324  1.00 38.08  ? 901  VAL A N     1 
ATOM   5117  C  CA    . VAL A 1 883  ? 151.242 121.172 79.183  1.00 38.08  ? 901  VAL A CA    1 
ATOM   5118  C  C     . VAL A 1 883  ? 150.689 121.902 77.968  1.00 38.08  ? 901  VAL A C     1 
ATOM   5119  O  O     . VAL A 1 883  ? 151.032 121.560 76.831  1.00 38.08  ? 901  VAL A O     1 
ATOM   5120  C  CB    . VAL A 1 883  ? 150.408 119.921 79.521  1.00 38.08  ? 901  VAL A CB    1 
ATOM   5121  C  CG1   . VAL A 1 883  ? 151.115 119.099 80.580  1.00 38.08  ? 901  VAL A CG1   1 
ATOM   5122  C  CG2   . VAL A 1 883  ? 149.012 120.291 79.963  1.00 38.08  ? 901  VAL A CG2   1 
ATOM   5123  N  N     . LEU A 1 884  ? 149.843 122.916 78.170  1.00 41.57  ? 902  LEU A N     1 
ATOM   5124  C  CA    . LEU A 1 884  ? 149.435 123.747 77.038  1.00 41.57  ? 902  LEU A CA    1 
ATOM   5125  C  C     . LEU A 1 884  ? 150.647 124.399 76.383  1.00 41.57  ? 902  LEU A C     1 
ATOM   5126  O  O     . LEU A 1 884  ? 150.821 124.339 75.157  1.00 41.57  ? 902  LEU A O     1 
ATOM   5127  C  CB    . LEU A 1 884  ? 148.432 124.809 77.493  1.00 41.57  ? 902  LEU A CB    1 
ATOM   5128  C  CG    . LEU A 1 884  ? 147.066 124.340 78.001  1.00 41.57  ? 902  LEU A CG    1 
ATOM   5129  C  CD1   . LEU A 1 884  ? 146.166 125.525 78.317  1.00 41.57  ? 902  LEU A CD1   1 
ATOM   5130  C  CD2   . LEU A 1 884  ? 146.406 123.425 76.996  1.00 41.57  ? 902  LEU A CD2   1 
ATOM   5131  N  N     . GLY A 1 885  ? 151.511 125.011 77.194  1.00 45.05  ? 903  GLY A N     1 
ATOM   5132  C  CA    . GLY A 1 885  ? 152.713 125.625 76.651  1.00 45.05  ? 903  GLY A CA    1 
ATOM   5133  C  C     . GLY A 1 885  ? 153.659 124.616 76.027  1.00 45.05  ? 903  GLY A C     1 
ATOM   5134  O  O     . GLY A 1 885  ? 154.311 124.901 75.020  1.00 45.05  ? 903  GLY A O     1 
ATOM   5135  N  N     . ASP A 1 886  ? 153.754 123.426 76.625  1.00 46.32  ? 904  ASP A N     1 
ATOM   5136  C  CA    . ASP A 1 886  ? 154.605 122.377 76.077  1.00 46.32  ? 904  ASP A CA    1 
ATOM   5137  C  C     . ASP A 1 886  ? 154.123 121.949 74.699  1.00 46.32  ? 904  ASP A C     1 
ATOM   5138  O  O     . ASP A 1 886  ? 154.916 121.828 73.760  1.00 46.32  ? 904  ASP A O     1 
ATOM   5139  C  CB    . ASP A 1 886  ? 154.643 121.177 77.026  1.00 46.32  ? 904  ASP A CB    1 
ATOM   5140  C  CG    . ASP A 1 886  ? 155.277 121.508 78.363  1.00 46.32  ? 904  ASP A CG    1 
ATOM   5141  O  OD1   . ASP A 1 886  ? 156.125 122.422 78.411  1.00 46.32  ? 904  ASP A OD1   1 
ATOM   5142  O  OD2   . ASP A 1 886  ? 154.924 120.855 79.369  1.00 46.32  ? 904  ASP A OD2   1 
ATOM   5143  N  N     . ALA A 1 887  ? 152.815 121.723 74.560  1.00 42.01  ? 905  ALA A N     1 
ATOM   5144  C  CA    . ALA A 1 887  ? 152.260 121.341 73.267  1.00 42.01  ? 905  ALA A CA    1 
ATOM   5145  C  C     . ALA A 1 887  ? 152.454 122.442 72.236  1.00 42.01  ? 905  ALA A C     1 
ATOM   5146  O  O     . ALA A 1 887  ? 152.751 122.161 71.069  1.00 42.01  ? 905  ALA A O     1 
ATOM   5147  C  CB    . ALA A 1 887  ? 150.779 121.004 73.411  1.00 42.01  ? 905  ALA A CB    1 
ATOM   5148  N  N     . HIS A 1 888  ? 152.278 123.702 72.640  1.00 46.05  ? 906  HIS A N     1 
ATOM   5149  C  CA    . HIS A 1 888  ? 152.512 124.793 71.700  1.00 46.05  ? 906  HIS A CA    1 
ATOM   5150  C  C     . HIS A 1 888  ? 153.970 124.841 71.256  1.00 46.05  ? 906  HIS A C     1 
ATOM   5151  O  O     . HIS A 1 888  ? 154.259 125.058 70.074  1.00 46.05  ? 906  HIS A O     1 
ATOM   5152  C  CB    . HIS A 1 888  ? 152.099 126.129 72.316  1.00 46.05  ? 906  HIS A CB    1 
ATOM   5153  C  CG    . HIS A 1 888  ? 152.286 127.298 71.398  1.00 46.05  ? 906  HIS A CG    1 
ATOM   5154  N  ND1   . HIS A 1 888  ? 153.474 127.989 71.306  1.00 46.05  ? 906  HIS A ND1   1 
ATOM   5155  C  CD2   . HIS A 1 888  ? 151.436 127.893 70.528  1.00 46.05  ? 906  HIS A CD2   1 
ATOM   5156  C  CE1   . HIS A 1 888  ? 153.349 128.962 70.421  1.00 46.05  ? 906  HIS A CE1   1 
ATOM   5157  N  NE2   . HIS A 1 888  ? 152.121 128.926 69.935  1.00 46.05  ? 906  HIS A NE2   1 
ATOM   5158  N  N     . PHE A 1 889  ? 154.903 124.634 72.187  1.00 50.30  ? 907  PHE A N     1 
ATOM   5159  C  CA    . PHE A 1 889  ? 156.319 124.787 71.866  1.00 50.30  ? 907  PHE A CA    1 
ATOM   5160  C  C     . PHE A 1 889  ? 156.866 123.574 71.120  1.00 50.30  ? 907  PHE A C     1 
ATOM   5161  O  O     . PHE A 1 889  ? 157.569 123.722 70.114  1.00 50.30  ? 907  PHE A O     1 
ATOM   5162  C  CB    . PHE A 1 889  ? 157.116 125.033 73.147  1.00 50.30  ? 907  PHE A CB    1 
ATOM   5163  C  CG    . PHE A 1 889  ? 158.555 125.382 72.911  1.00 50.30  ? 907  PHE A CG    1 
ATOM   5164  C  CD1   . PHE A 1 889  ? 158.898 126.538 72.232  1.00 50.30  ? 907  PHE A CD1   1 
ATOM   5165  C  CD2   . PHE A 1 889  ? 159.565 124.565 73.382  1.00 50.30  ? 907  PHE A CD2   1 
ATOM   5166  C  CE1   . PHE A 1 889  ? 160.219 126.867 72.020  1.00 50.30  ? 907  PHE A CE1   1 
ATOM   5167  C  CE2   . PHE A 1 889  ? 160.889 124.889 73.173  1.00 50.30  ? 907  PHE A CE2   1 
ATOM   5168  C  CZ    . PHE A 1 889  ? 161.217 126.041 72.491  1.00 50.30  ? 907  PHE A CZ    1 
ATOM   5169  N  N     . ALA A 1 890  ? 156.562 122.375 71.599  1.00 48.42  ? 908  ALA A N     1 
ATOM   5170  C  CA    . ALA A 1 890  ? 157.071 121.148 70.996  1.00 48.42  ? 908  ALA A CA    1 
ATOM   5171  C  C     . ALA A 1 890  ? 156.044 120.045 71.227  1.00 48.42  ? 908  ALA A C     1 
ATOM   5172  O  O     . ALA A 1 890  ? 154.881 120.317 71.539  1.00 48.42  ? 908  ALA A O     1 
ATOM   5173  C  CB    . ALA A 1 890  ? 158.461 120.808 71.561  1.00 48.42  ? 908  ALA A CB    1 
ATOM   5174  N  N     . GLY A 1 891  ? 156.464 118.794 71.049  1.00 51.39  ? 909  GLY A N     1 
ATOM   5175  C  CA    . GLY A 1 891  ? 155.600 117.654 71.270  1.00 51.39  ? 909  GLY A CA    1 
ATOM   5176  C  C     . GLY A 1 891  ? 155.888 116.842 72.512  1.00 51.39  ? 909  GLY A C     1 
ATOM   5177  O  O     . GLY A 1 891  ? 155.347 115.736 72.645  1.00 51.39  ? 909  GLY A O     1 
ATOM   5178  N  N     . MET A 1 892  ? 156.720 117.334 73.427  1.00 55.86  ? 910  MET A N     1 
ATOM   5179  C  CA    . MET A 1 892  ? 157.122 116.568 74.596  1.00 55.86  ? 910  MET A CA    1 
ATOM   5180  C  C     . MET A 1 892  ? 157.065 117.447 75.836  1.00 55.86  ? 910  MET A C     1 
ATOM   5181  O  O     . MET A 1 892  ? 157.188 118.672 75.758  1.00 55.86  ? 910  MET A O     1 
ATOM   5182  C  CB    . MET A 1 892  ? 158.532 115.991 74.422  1.00 55.86  ? 910  MET A CB    1 
ATOM   5183  C  CG    . MET A 1 892  ? 159.562 117.020 73.994  1.00 55.86  ? 910  MET A CG    1 
ATOM   5184  S  SD    . MET A 1 892  ? 161.112 116.273 73.464  1.00 55.86  ? 910  MET A SD    1 
ATOM   5185  C  CE    . MET A 1 892  ? 161.995 117.719 72.892  1.00 55.86  ? 910  MET A CE    1 
ATOM   5186  N  N     . HIS A 1 893  ? 156.877 116.801 76.984  1.00 44.42  ? 911  HIS A N     1 
ATOM   5187  C  CA    . HIS A 1 893  ? 156.804 117.513 78.250  1.00 44.42  ? 911  HIS A CA    1 
ATOM   5188  C  C     . HIS A 1 893  ? 158.161 118.093 78.626  1.00 44.42  ? 911  HIS A C     1 
ATOM   5189  O  O     . HIS A 1 893  ? 159.213 117.527 78.320  1.00 44.42  ? 911  HIS A O     1 
ATOM   5190  C  CB    . HIS A 1 893  ? 156.315 116.579 79.356  1.00 44.42  ? 911  HIS A CB    1 
ATOM   5191  C  CG    . HIS A 1 893  ? 155.027 115.891 79.038  1.00 44.42  ? 911  HIS A CG    1 
ATOM   5192  N  ND1   . HIS A 1 893  ? 153.830 116.247 79.619  1.00 44.42  ? 911  HIS A ND1   1 
ATOM   5193  C  CD2   . HIS A 1 893  ? 154.747 114.868 78.196  1.00 44.42  ? 911  HIS A CD2   1 
ATOM   5194  C  CE1   . HIS A 1 893  ? 152.868 115.472 79.152  1.00 44.42  ? 911  HIS A CE1   1 
ATOM   5195  N  NE2   . HIS A 1 893  ? 153.398 114.628 78.286  1.00 44.42  ? 911  HIS A NE2   1 
ATOM   5196  N  N     . GLY A 1 894  ? 158.128 119.242 79.294  1.00 51.75  ? 912  GLY A N     1 
ATOM   5197  C  CA    . GLY A 1 894  ? 159.334 119.891 79.756  1.00 51.75  ? 912  GLY A CA    1 
ATOM   5198  C  C     . GLY A 1 894  ? 160.075 120.700 78.717  1.00 51.75  ? 912  GLY A C     1 
ATOM   5199  O  O     . GLY A 1 894  ? 161.142 121.244 79.030  1.00 51.75  ? 912  GLY A O     1 
ATOM   5200  N  N     . CYS A 1 895  ? 159.556 120.800 77.492  1.00 51.51  ? 913  CYS A N     1 
ATOM   5201  C  CA    . CYS A 1 895  ? 160.225 121.600 76.474  1.00 51.51  ? 913  CYS A CA    1 
ATOM   5202  C  C     . CYS A 1 895  ? 160.188 123.087 76.798  1.00 51.51  ? 913  CYS A C     1 
ATOM   5203  O  O     . CYS A 1 895  ? 161.015 123.844 76.282  1.00 51.51  ? 913  CYS A O     1 
ATOM   5204  C  CB    . CYS A 1 895  ? 159.598 121.343 75.104  1.00 51.51  ? 913  CYS A CB    1 
ATOM   5205  S  SG    . CYS A 1 895  ? 157.862 121.784 74.988  1.00 51.51  ? 913  CYS A SG    1 
ATOM   5206  N  N     . THR A 1 896  ? 159.251 123.514 77.634  1.00 52.01  ? 914  THR A N     1 
ATOM   5207  C  CA    . THR A 1 896  ? 159.204 124.874 78.144  1.00 52.01  ? 914  THR A CA    1 
ATOM   5208  C  C     . THR A 1 896  ? 159.755 124.907 79.563  1.00 52.01  ? 914  THR A C     1 
ATOM   5209  O  O     . THR A 1 896  ? 159.602 123.952 80.328  1.00 52.01  ? 914  THR A O     1 
ATOM   5210  C  CB    . THR A 1 896  ? 157.774 125.418 78.132  1.00 52.01  ? 914  THR A CB    1 
ATOM   5211  O  OG1   . THR A 1 896  ? 156.894 124.464 78.738  1.00 52.01  ? 914  THR A OG1   1 
ATOM   5212  C  CG2   . THR A 1 896  ? 157.319 125.690 76.712  1.00 52.01  ? 914  THR A CG2   1 
ATOM   5213  N  N     . ALA A 1 897  ? 160.409 126.020 79.904  1.00 52.50  ? 915  ALA A N     1 
ATOM   5214  C  CA    . ALA A 1 897  ? 160.972 126.167 81.242  1.00 52.50  ? 915  ALA A CA    1 
ATOM   5215  C  C     . ALA A 1 897  ? 159.901 126.004 82.314  1.00 52.50  ? 915  ALA A C     1 
ATOM   5216  O  O     . ALA A 1 897  ? 160.160 125.433 83.381  1.00 52.50  ? 915  ALA A O     1 
ATOM   5217  C  CB    . ALA A 1 897  ? 161.663 127.523 81.372  1.00 52.50  ? 915  ALA A CB    1 
ATOM   5218  N  N     . PHE A 1 898  ? 158.690 126.494 82.045  1.00 52.08  ? 916  PHE A N     1 
ATOM   5219  C  CA    . PHE A 1 898  ? 157.596 126.338 82.997  1.00 52.08  ? 916  PHE A CA    1 
ATOM   5220  C  C     . PHE A 1 898  ? 157.257 124.868 83.208  1.00 52.08  ? 916  PHE A C     1 
ATOM   5221  O  O     . PHE A 1 898  ? 156.999 124.440 84.338  1.00 52.08  ? 916  PHE A O     1 
ATOM   5222  C  CB    . PHE A 1 898  ? 156.374 127.119 82.513  1.00 52.08  ? 916  PHE A CB    1 
ATOM   5223  C  CG    . PHE A 1 898  ? 155.215 127.092 83.466  1.00 52.08  ? 916  PHE A CG    1 
ATOM   5224  C  CD1   . PHE A 1 898  ? 155.371 127.495 84.779  1.00 52.08  ? 916  PHE A CD1   1 
ATOM   5225  C  CD2   . PHE A 1 898  ? 153.964 126.681 83.042  1.00 52.08  ? 916  PHE A CD2   1 
ATOM   5226  C  CE1   . PHE A 1 898  ? 154.305 127.473 85.655  1.00 52.08  ? 916  PHE A CE1   1 
ATOM   5227  C  CE2   . PHE A 1 898  ? 152.893 126.659 83.914  1.00 52.08  ? 916  PHE A CE2   1 
ATOM   5228  C  CZ    . PHE A 1 898  ? 153.064 127.056 85.221  1.00 52.08  ? 916  PHE A CZ    1 
ATOM   5229  N  N     . GLY A 1 899  ? 157.268 124.077 82.133  1.00 53.48  ? 917  GLY A N     1 
ATOM   5230  C  CA    . GLY A 1 899  ? 157.015 122.653 82.275  1.00 53.48  ? 917  GLY A CA    1 
ATOM   5231  C  C     . GLY A 1 899  ? 158.089 121.942 83.076  1.00 53.48  ? 917  GLY A C     1 
ATOM   5232  O  O     . GLY A 1 899  ? 157.792 121.049 83.874  1.00 53.48  ? 917  GLY A O     1 
ATOM   5233  N  N     . TRP A 1 900  ? 159.352 122.325 82.877  1.00 62.17  ? 918  TRP A N     1 
ATOM   5234  C  CA    . TRP A 1 900  ? 160.432 121.750 83.673  1.00 62.17  ? 918  TRP A CA    1 
ATOM   5235  C  C     . TRP A 1 900  ? 160.266 122.098 85.146  1.00 62.17  ? 918  TRP A C     1 
ATOM   5236  O  O     . TRP A 1 900  ? 160.375 121.228 86.018  1.00 62.17  ? 918  TRP A O     1 
ATOM   5237  C  CB    . TRP A 1 900  ? 161.787 122.235 83.155  1.00 62.17  ? 918  TRP A CB    1 
ATOM   5238  C  CG    . TRP A 1 900  ? 162.955 121.726 83.956  1.00 62.17  ? 918  TRP A CG    1 
ATOM   5239  C  CD1   . TRP A 1 900  ? 163.486 122.286 85.082  1.00 62.17  ? 918  TRP A CD1   1 
ATOM   5240  C  CD2   . TRP A 1 900  ? 163.735 120.554 83.688  1.00 62.17  ? 918  TRP A CD2   1 
ATOM   5241  N  NE1   . TRP A 1 900  ? 164.545 121.537 85.531  1.00 62.17  ? 918  TRP A NE1   1 
ATOM   5242  C  CE2   . TRP A 1 900  ? 164.719 120.468 84.693  1.00 62.17  ? 918  TRP A CE2   1 
ATOM   5243  C  CE3   . TRP A 1 900  ? 163.696 119.570 82.696  1.00 62.17  ? 918  TRP A CE3   1 
ATOM   5244  C  CZ2   . TRP A 1 900  ? 165.655 119.437 84.734  1.00 62.17  ? 918  TRP A CZ2   1 
ATOM   5245  C  CZ3   . TRP A 1 900  ? 164.627 118.548 82.739  1.00 62.17  ? 918  TRP A CZ3   1 
ATOM   5246  C  CH2   . TRP A 1 900  ? 165.593 118.489 83.751  1.00 62.17  ? 918  TRP A CH2   1 
ATOM   5247  N  N     . MET A 1 901  ? 160.007 123.374 85.443  1.00 57.23  ? 919  MET A N     1 
ATOM   5248  C  CA    . MET A 1 901  ? 159.853 123.790 86.833  1.00 57.23  ? 919  MET A CA    1 
ATOM   5249  C  C     . MET A 1 901  ? 158.667 123.097 87.489  1.00 57.23  ? 919  MET A C     1 
ATOM   5250  O  O     . MET A 1 901  ? 158.726 122.732 88.668  1.00 57.23  ? 919  MET A O     1 
ATOM   5251  C  CB    . MET A 1 901  ? 159.707 125.308 86.914  1.00 57.23  ? 919  MET A CB    1 
ATOM   5252  C  CG    . MET A 1 901  ? 160.947 126.064 86.471  1.00 57.23  ? 919  MET A CG    1 
ATOM   5253  S  SD    . MET A 1 901  ? 160.749 127.853 86.539  1.00 57.23  ? 919  MET A SD    1 
ATOM   5254  C  CE    . MET A 1 901  ? 162.359 128.392 85.970  1.00 57.23  ? 919  MET A CE    1 
ATOM   5255  N  N     . THR A 1 902  ? 157.576 122.914 86.745  1.00 53.52  ? 920  THR A N     1 
ATOM   5256  C  CA    . THR A 1 902  ? 156.440 122.175 87.283  1.00 53.52  ? 920  THR A CA    1 
ATOM   5257  C  C     . THR A 1 902  ? 156.798 120.714 87.525  1.00 53.52  ? 920  THR A C     1 
ATOM   5258  O  O     . THR A 1 902  ? 156.396 120.130 88.538  1.00 53.52  ? 920  THR A O     1 
ATOM   5259  C  CB    . THR A 1 902  ? 155.245 122.288 86.337  1.00 53.52  ? 920  THR A CB    1 
ATOM   5260  O  OG1   . THR A 1 902  ? 154.917 123.670 86.150  1.00 53.52  ? 920  THR A OG1   1 
ATOM   5261  C  CG2   . THR A 1 902  ? 154.041 121.566 86.912  1.00 53.52  ? 920  THR A CG2   1 
ATOM   5262  N  N     . LEU A 1 903  ? 157.562 120.109 86.614  1.00 55.22  ? 921  LEU A N     1 
ATOM   5263  C  CA    . LEU A 1 903  ? 157.858 118.684 86.714  1.00 55.22  ? 921  LEU A CA    1 
ATOM   5264  C  C     . LEU A 1 903  ? 159.056 118.414 87.618  1.00 55.22  ? 921  LEU A C     1 
ATOM   5265  O  O     . LEU A 1 903  ? 158.947 117.689 88.613  1.00 55.22  ? 921  LEU A O     1 
ATOM   5266  C  CB    . LEU A 1 903  ? 158.101 118.103 85.319  1.00 55.22  ? 921  LEU A CB    1 
ATOM   5267  C  CG    . LEU A 1 903  ? 156.900 117.999 84.380  1.00 55.22  ? 921  LEU A CG    1 
ATOM   5268  C  CD1   . LEU A 1 903  ? 157.347 117.535 83.006  1.00 55.22  ? 921  LEU A CD1   1 
ATOM   5269  C  CD2   . LEU A 1 903  ? 155.857 117.057 84.948  1.00 55.22  ? 921  LEU A CD2   1 
ATOM   5270  N  N     . GLN A 1 904  ? 160.211 118.989 87.286  1.00 60.64  ? 922  GLN A N     1 
ATOM   5271  C  CA    . GLN A 1 904  ? 161.453 118.639 87.962  1.00 60.64  ? 922  GLN A CA    1 
ATOM   5272  C  C     . GLN A 1 904  ? 161.730 119.481 89.200  1.00 60.64  ? 922  GLN A C     1 
ATOM   5273  O  O     . GLN A 1 904  ? 162.516 119.056 90.054  1.00 60.64  ? 922  GLN A O     1 
ATOM   5274  C  CB    . GLN A 1 904  ? 162.628 118.755 86.987  1.00 60.64  ? 922  GLN A CB    1 
ATOM   5275  C  CG    . GLN A 1 904  ? 162.437 117.954 85.707  1.00 60.64  ? 922  GLN A CG    1 
ATOM   5276  C  CD    . GLN A 1 904  ? 162.079 116.501 85.971  1.00 60.64  ? 922  GLN A CD    1 
ATOM   5277  O  OE1   . GLN A 1 904  ? 160.904 116.138 86.026  1.00 60.64  ? 922  GLN A OE1   1 
ATOM   5278  N  NE2   . GLN A 1 904  ? 163.095 115.661 86.131  1.00 60.64  ? 922  GLN A NE2   1 
ATOM   5279  N  N     . GLY A 1 905  ? 161.116 120.654 89.320  1.00 64.17  ? 923  GLY A N     1 
ATOM   5280  C  CA    . GLY A 1 905  ? 161.284 121.445 90.522  1.00 64.17  ? 923  GLY A CA    1 
ATOM   5281  C  C     . GLY A 1 905  ? 160.574 120.824 91.710  1.00 64.17  ? 923  GLY A C     1 
ATOM   5282  O  O     . GLY A 1 905  ? 159.518 120.204 91.584  1.00 64.17  ? 923  GLY A O     1 
ATOM   5283  N  N     . ARG A 1 906  ? 161.170 120.997 92.887  1.00 73.11  ? 924  ARG A N     1 
ATOM   5284  C  CA    . ARG A 1 906  ? 160.630 120.442 94.119  1.00 73.11  ? 924  ARG A CA    1 
ATOM   5285  C  C     . ARG A 1 906  ? 160.601 121.508 95.203  1.00 73.11  ? 924  ARG A C     1 
ATOM   5286  O  O     . ARG A 1 906  ? 161.431 122.421 95.225  1.00 73.11  ? 924  ARG A O     1 
ATOM   5287  C  CB    . ARG A 1 906  ? 161.446 119.235 94.603  1.00 73.11  ? 924  ARG A CB    1 
ATOM   5288  C  CG    . ARG A 1 906  ? 161.281 117.990 93.749  1.00 73.11  ? 924  ARG A CG    1 
ATOM   5289  C  CD    . ARG A 1 906  ? 159.818 117.594 93.632  1.00 73.11  ? 924  ARG A CD    1 
ATOM   5290  N  NE    . ARG A 1 906  ? 159.652 116.303 92.977  1.00 73.11  ? 924  ARG A NE    1 
ATOM   5291  C  CZ    . ARG A 1 906  ? 159.627 116.125 91.663  1.00 73.11  ? 924  ARG A CZ    1 
ATOM   5292  N  NH1   . ARG A 1 906  ? 159.766 117.140 90.826  1.00 73.11  ? 924  ARG A NH1   1 
ATOM   5293  N  NH2   . ARG A 1 906  ? 159.459 114.898 91.178  1.00 73.11  ? 924  ARG A NH2   1 
ATOM   5294  N  N     . LYS A 1 907  ? 159.627 121.378 96.106  1.00 75.93  ? 925  LYS A N     1 
ATOM   5295  C  CA    . LYS A 1 907  ? 159.499 122.313 97.217  1.00 75.93  ? 925  LYS A CA    1 
ATOM   5296  C  C     . LYS A 1 907  ? 160.563 122.091 98.284  1.00 75.93  ? 925  LYS A C     1 
ATOM   5297  O  O     . LYS A 1 907  ? 160.890 123.029 99.020  1.00 75.93  ? 925  LYS A O     1 
ATOM   5298  C  CB    . LYS A 1 907  ? 158.100 122.201 97.829  1.00 75.93  ? 925  LYS A CB    1 
ATOM   5299  C  CG    . LYS A 1 907  ? 157.796 123.230 98.907  1.00 75.93  ? 925  LYS A CG    1 
ATOM   5300  C  CD    . LYS A 1 907  ? 156.306 123.304 99.200  1.00 75.93  ? 925  LYS A CD    1 
ATOM   5301  C  CE    . LYS A 1 907  ? 155.751 121.962 99.642  1.00 75.93  ? 925  LYS A CE    1 
ATOM   5302  N  NZ    . LYS A 1 907  ? 154.291 122.046 99.922  1.00 75.93  ? 925  LYS A NZ    1 
ATOM   5303  N  N     . SER A 1 908  ? 161.113 120.878 98.381  1.00 79.15  ? 926  SER A N     1 
ATOM   5304  C  CA    . SER A 1 908  ? 162.128 120.602 99.394  1.00 79.15  ? 926  SER A CA    1 
ATOM   5305  C  C     . SER A 1 908  ? 163.361 121.473 99.195  1.00 79.15  ? 926  SER A C     1 
ATOM   5306  O  O     . SER A 1 908  ? 163.904 122.024 100.160 1.00 79.15  ? 926  SER A O     1 
ATOM   5307  C  CB    . SER A 1 908  ? 162.508 119.122 99.365  1.00 79.15  ? 926  SER A CB    1 
ATOM   5308  O  OG    . SER A 1 908  ? 163.115 118.778 98.132  1.00 79.15  ? 926  SER A OG    1 
ATOM   5309  N  N     . ARG A 1 909  ? 163.817 121.611 97.954  1.00 79.52  ? 927  ARG A N     1 
ATOM   5310  C  CA    . ARG A 1 909  ? 164.955 122.460 97.634  1.00 79.52  ? 927  ARG A CA    1 
ATOM   5311  C  C     . ARG A 1 909  ? 164.551 123.885 97.286  1.00 79.52  ? 927  ARG A C     1 
ATOM   5312  O  O     . ARG A 1 909  ? 165.427 124.709 97.001  1.00 79.52  ? 927  ARG A O     1 
ATOM   5313  C  CB    . ARG A 1 909  ? 165.750 121.865 96.469  1.00 79.52  ? 927  ARG A CB    1 
ATOM   5314  C  CG    . ARG A 1 909  ? 166.518 120.602 96.803  1.00 79.52  ? 927  ARG A CG    1 
ATOM   5315  C  CD    . ARG A 1 909  ? 167.180 120.045 95.556  1.00 79.52  ? 927  ARG A CD    1 
ATOM   5316  N  NE    . ARG A 1 909  ? 167.823 121.098 94.778  1.00 79.52  ? 927  ARG A NE    1 
ATOM   5317  C  CZ    . ARG A 1 909  ? 168.418 120.909 93.608  1.00 79.52  ? 927  ARG A CZ    1 
ATOM   5318  N  NH1   . ARG A 1 909  ? 168.478 119.712 93.049  1.00 79.52  ? 927  ARG A NH1   1 
ATOM   5319  N  NH2   . ARG A 1 909  ? 168.964 121.948 92.984  1.00 79.52  ? 927  ARG A NH2   1 
ATOM   5320  N  N     . GLY A 1 910  ? 163.258 124.196 97.302  1.00 73.63  ? 928  GLY A N     1 
ATOM   5321  C  CA    . GLY A 1 910  ? 162.814 125.503 96.865  1.00 73.63  ? 928  GLY A CA    1 
ATOM   5322  C  C     . GLY A 1 910  ? 162.955 125.739 95.380  1.00 73.63  ? 928  GLY A C     1 
ATOM   5323  O  O     . GLY A 1 910  ? 163.019 126.893 94.948  1.00 73.63  ? 928  GLY A O     1 
ATOM   5324  N  N     . THR A 1 911  ? 163.007 124.674 94.584  1.00 73.78  ? 929  THR A N     1 
ATOM   5325  C  CA    . THR A 1 911  ? 163.214 124.770 93.146  1.00 73.78  ? 929  THR A CA    1 
ATOM   5326  C  C     . THR A 1 911  ? 161.916 124.834 92.352  1.00 73.78  ? 929  THR A C     1 
ATOM   5327  O  O     . THR A 1 911  ? 161.966 125.006 91.130  1.00 73.78  ? 929  THR A O     1 
ATOM   5328  C  CB    . THR A 1 911  ? 164.049 123.584 92.653  1.00 73.78  ? 929  THR A CB    1 
ATOM   5329  O  OG1   . THR A 1 911  ? 163.421 122.358 93.050  1.00 73.78  ? 929  THR A OG1   1 
ATOM   5330  C  CG2   . THR A 1 911  ? 165.452 123.642 93.234  1.00 73.78  ? 929  THR A CG2   1 
ATOM   5331  N  N     . ASP A 1 912  ? 160.762 124.697 93.001  1.00 71.07  ? 930  ASP A N     1 
ATOM   5332  C  CA    . ASP A 1 912  ? 159.501 124.764 92.281  1.00 71.07  ? 930  ASP A CA    1 
ATOM   5333  C  C     . ASP A 1 912  ? 159.145 126.219 91.985  1.00 71.07  ? 930  ASP A C     1 
ATOM   5334  O  O     . ASP A 1 912  ? 159.858 127.152 92.363  1.00 71.07  ? 930  ASP A O     1 
ATOM   5335  C  CB    . ASP A 1 912  ? 158.396 124.061 93.066  1.00 71.07  ? 930  ASP A CB    1 
ATOM   5336  C  CG    . ASP A 1 912  ? 158.119 124.716 94.399  1.00 71.07  ? 930  ASP A CG    1 
ATOM   5337  O  OD1   . ASP A 1 912  ? 159.069 125.253 95.004  1.00 71.07  ? 930  ASP A OD1   1 
ATOM   5338  O  OD2   . ASP A 1 912  ? 156.952 124.693 94.842  1.00 71.07  ? 930  ASP A OD2   1 
ATOM   5339  N  N     . LEU A 1 913  ? 158.019 126.414 91.296  1.00 65.58  ? 931  LEU A N     1 
ATOM   5340  C  CA    . LEU A 1 913  ? 157.658 127.741 90.806  1.00 65.58  ? 931  LEU A CA    1 
ATOM   5341  C  C     . LEU A 1 913  ? 157.438 128.723 91.950  1.00 65.58  ? 931  LEU A C     1 
ATOM   5342  O  O     . LEU A 1 913  ? 157.989 129.830 91.947  1.00 65.58  ? 931  LEU A O     1 
ATOM   5343  C  CB    . LEU A 1 913  ? 156.407 127.650 89.934  1.00 65.58  ? 931  LEU A CB    1 
ATOM   5344  C  CG    . LEU A 1 913  ? 155.881 128.984 89.405  1.00 65.58  ? 931  LEU A CG    1 
ATOM   5345  C  CD1   . LEU A 1 913  ? 156.814 129.544 88.341  1.00 65.58  ? 931  LEU A CD1   1 
ATOM   5346  C  CD2   . LEU A 1 913  ? 154.467 128.835 88.871  1.00 65.58  ? 931  LEU A CD2   1 
ATOM   5347  N  N     . HIS A 1 914  ? 156.627 128.337 92.937  1.00 65.52  ? 932  HIS A N     1 
ATOM   5348  C  CA    . HIS A 1 914  ? 156.255 129.263 94.003  1.00 65.52  ? 932  HIS A CA    1 
ATOM   5349  C  C     . HIS A 1 914  ? 157.471 129.690 94.817  1.00 65.52  ? 932  HIS A C     1 
ATOM   5350  O  O     . HIS A 1 914  ? 157.673 130.883 95.077  1.00 65.52  ? 932  HIS A O     1 
ATOM   5351  C  CB    . HIS A 1 914  ? 155.200 128.621 94.903  1.00 65.52  ? 932  HIS A CB    1 
ATOM   5352  C  CG    . HIS A 1 914  ? 153.903 128.340 94.209  1.00 65.52  ? 932  HIS A CG    1 
ATOM   5353  N  ND1   . HIS A 1 914  ? 153.529 128.975 93.045  1.00 65.52  ? 932  HIS A ND1   1 
ATOM   5354  C  CD2   . HIS A 1 914  ? 152.893 127.493 94.517  1.00 65.52  ? 932  HIS A CD2   1 
ATOM   5355  C  CE1   . HIS A 1 914  ? 152.343 128.533 92.666  1.00 65.52  ? 932  HIS A CE1   1 
ATOM   5356  N  NE2   . HIS A 1 914  ? 151.935 127.633 93.542  1.00 65.52  ? 932  HIS A NE2   1 
ATOM   5357  N  N     . SER A 1 915  ? 158.301 128.727 95.221  1.00 67.43  ? 933  SER A N     1 
ATOM   5358  C  CA    . SER A 1 915  ? 159.475 129.060 96.021  1.00 67.43  ? 933  SER A CA    1 
ATOM   5359  C  C     . SER A 1 915  ? 160.498 129.838 95.205  1.00 67.43  ? 933  SER A C     1 
ATOM   5360  O  O     . SER A 1 915  ? 161.164 130.736 95.733  1.00 67.43  ? 933  SER A O     1 
ATOM   5361  C  CB    . SER A 1 915  ? 160.095 127.790 96.597  1.00 67.43  ? 933  SER A CB    1 
ATOM   5362  O  OG    . SER A 1 915  ? 159.166 127.095 97.410  1.00 67.43  ? 933  SER A OG    1 
ATOM   5363  N  N     . LYS A 1 916  ? 160.642 129.508 93.920  1.00 64.00  ? 934  LYS A N     1 
ATOM   5364  C  CA    . LYS A 1 916  ? 161.547 130.269 93.064  1.00 64.00  ? 934  LYS A CA    1 
ATOM   5365  C  C     . LYS A 1 916  ? 161.100 131.721 92.953  1.00 64.00  ? 934  LYS A C     1 
ATOM   5366  O  O     . LYS A 1 916  ? 161.922 132.641 93.044  1.00 64.00  ? 934  LYS A O     1 
ATOM   5367  C  CB    . LYS A 1 916  ? 161.627 129.628 91.679  1.00 64.00  ? 934  LYS A CB    1 
ATOM   5368  C  CG    . LYS A 1 916  ? 162.601 130.305 90.731  1.00 64.00  ? 934  LYS A CG    1 
ATOM   5369  C  CD    . LYS A 1 916  ? 164.040 129.976 91.089  1.00 64.00  ? 934  LYS A CD    1 
ATOM   5370  C  CE    . LYS A 1 916  ? 164.321 128.492 90.918  1.00 64.00  ? 934  LYS A CE    1 
ATOM   5371  N  NZ    . LYS A 1 916  ? 165.743 128.156 91.202  1.00 64.00  ? 934  LYS A NZ    1 
ATOM   5372  N  N     . THR A 1 917  ? 159.797 131.944 92.765  1.00 63.55  ? 935  THR A N     1 
ATOM   5373  C  CA    . THR A 1 917  ? 159.278 133.307 92.704  1.00 63.55  ? 935  THR A CA    1 
ATOM   5374  C  C     . THR A 1 917  ? 159.496 134.034 94.024  1.00 63.55  ? 935  THR A C     1 
ATOM   5375  O  O     . THR A 1 917  ? 159.894 135.205 94.040  1.00 63.55  ? 935  THR A O     1 
ATOM   5376  C  CB    . THR A 1 917  ? 157.793 133.286 92.342  1.00 63.55  ? 935  THR A CB    1 
ATOM   5377  O  OG1   . THR A 1 917  ? 157.609 132.574 91.112  1.00 63.55  ? 935  THR A OG1   1 
ATOM   5378  C  CG2   . THR A 1 917  ? 157.262 134.701 92.183  1.00 63.55  ? 935  THR A CG2   1 
ATOM   5379  N  N     . ALA A 1 918  ? 159.248 133.348 95.143  1.00 66.93  ? 936  ALA A N     1 
ATOM   5380  C  CA    . ALA A 1 918  ? 159.444 133.966 96.450  1.00 66.93  ? 936  ALA A CA    1 
ATOM   5381  C  C     . ALA A 1 918  ? 160.899 134.366 96.660  1.00 66.93  ? 936  ALA A C     1 
ATOM   5382  O  O     . ALA A 1 918  ? 161.183 135.452 97.177  1.00 66.93  ? 936  ALA A O     1 
ATOM   5383  C  CB    . ALA A 1 918  ? 158.983 133.015 97.553  1.00 66.93  ? 936  ALA A CB    1 
ATOM   5384  N  N     . THR A 1 919  ? 161.835 133.498 96.271  1.00 66.71  ? 937  THR A N     1 
ATOM   5385  C  CA    . THR A 1 919  ? 163.251 133.824 96.413  1.00 66.71  ? 937  THR A CA    1 
ATOM   5386  C  C     . THR A 1 919  ? 163.654 134.972 95.496  1.00 66.71  ? 937  THR A C     1 
ATOM   5387  O  O     . THR A 1 919  ? 164.426 135.850 95.898  1.00 66.71  ? 937  THR A O     1 
ATOM   5388  C  CB    . THR A 1 919  ? 164.110 132.591 96.130  1.00 66.71  ? 937  THR A CB    1 
ATOM   5389  O  OG1   . THR A 1 919  ? 163.735 132.024 94.868  1.00 66.71  ? 937  THR A OG1   1 
ATOM   5390  C  CG2   . THR A 1 919  ? 163.932 131.553 97.227  1.00 66.71  ? 937  THR A CG2   1 
ATOM   5391  N  N     . THR A 1 920  ? 163.149 134.982 94.260  1.00 63.49  ? 938  THR A N     1 
ATOM   5392  C  CA    . THR A 1 920  ? 163.517 136.041 93.325  1.00 63.49  ? 938  THR A CA    1 
ATOM   5393  C  C     . THR A 1 920  ? 162.962 137.394 93.749  1.00 63.49  ? 938  THR A C     1 
ATOM   5394  O  O     . THR A 1 920  ? 163.611 138.423 93.528  1.00 63.49  ? 938  THR A O     1 
ATOM   5395  C  CB    . THR A 1 920  ? 163.038 135.698 91.914  1.00 63.49  ? 938  THR A CB    1 
ATOM   5396  O  OG1   . THR A 1 920  ? 161.650 135.347 91.950  1.00 63.49  ? 938  THR A OG1   1 
ATOM   5397  C  CG2   . THR A 1 920  ? 163.841 134.539 91.343  1.00 63.49  ? 938  THR A CG2   1 
ATOM   5398  N  N     . VAL A 1 921  ? 161.779 137.420 94.352  1.00 63.14  ? 939  VAL A N     1 
ATOM   5399  C  CA    . VAL A 1 921  ? 161.114 138.669 94.711  1.00 63.14  ? 939  VAL A CA    1 
ATOM   5400  C  C     . VAL A 1 921  ? 161.347 139.034 96.170  1.00 63.14  ? 939  VAL A C     1 
ATOM   5401  O  O     . VAL A 1 921  ? 161.709 140.168 96.483  1.00 63.14  ? 939  VAL A O     1 
ATOM   5402  C  CB    . VAL A 1 921  ? 159.607 138.579 94.388  1.00 63.14  ? 939  VAL A CB    1 
ATOM   5403  C  CG1   . VAL A 1 921  ? 158.925 139.906 94.672  1.00 63.14  ? 939  VAL A CG1   1 
ATOM   5404  C  CG2   . VAL A 1 921  ? 159.414 138.169 92.944  1.00 63.14  ? 939  VAL A CG2   1 
ATOM   5405  N  N     . GLY A 1 922  ? 161.144 138.085 97.080  1.00 64.07  ? 940  GLY A N     1 
ATOM   5406  C  CA    . GLY A 1 922  ? 161.313 138.358 98.493  1.00 64.07  ? 940  GLY A CA    1 
ATOM   5407  C  C     . GLY A 1 922  ? 160.003 138.498 99.240  1.00 64.07  ? 940  GLY A C     1 
ATOM   5408  O  O     . GLY A 1 922  ? 159.863 139.365 100.107 1.00 64.07  ? 940  GLY A O     1 
ATOM   5409  N  N     . ILE A 1 923  ? 159.033 137.646 98.910  1.00 66.92  ? 941  ILE A N     1 
ATOM   5410  C  CA    . ILE A 1 923  ? 157.737 137.626 99.571  1.00 66.92  ? 941  ILE A CA    1 
ATOM   5411  C  C     . ILE A 1 923  ? 157.481 136.214 100.081 1.00 66.92  ? 941  ILE A C     1 
ATOM   5412  O  O     . ILE A 1 923  ? 158.197 135.269 99.750  1.00 66.92  ? 941  ILE A O     1 
ATOM   5413  C  CB    . ILE A 1 923  ? 156.593 138.082 98.643  1.00 66.92  ? 941  ILE A CB    1 
ATOM   5414  C  CG1   . ILE A 1 923  ? 156.440 137.115 97.468  1.00 66.92  ? 941  ILE A CG1   1 
ATOM   5415  C  CG2   . ILE A 1 923  ? 156.841 139.497 98.146  1.00 66.92  ? 941  ILE A CG2   1 
ATOM   5416  C  CD1   . ILE A 1 923  ? 155.286 137.449 96.548  1.00 66.92  ? 941  ILE A CD1   1 
ATOM   5417  N  N     . SER A 1 924  ? 156.444 136.082 100.902 1.00 79.11  ? 942  SER A N     1 
ATOM   5418  C  CA    . SER A 1 924  ? 156.096 134.782 101.449 1.00 79.11  ? 942  SER A CA    1 
ATOM   5419  C  C     . SER A 1 924  ? 155.477 133.895 100.372 1.00 79.11  ? 942  SER A C     1 
ATOM   5420  O  O     . SER A 1 924  ? 155.028 134.363 99.322  1.00 79.11  ? 942  SER A O     1 
ATOM   5421  C  CB    . SER A 1 924  ? 155.130 134.931 102.623 1.00 79.11  ? 942  SER A CB    1 
ATOM   5422  O  OG    . SER A 1 924  ? 154.825 133.669 103.191 1.00 79.11  ? 942  SER A OG    1 
ATOM   5423  N  N     . ARG A 1 925  ? 155.462 132.589 100.647 1.00 75.80  ? 943  ARG A N     1 
ATOM   5424  C  CA    . ARG A 1 925  ? 154.883 131.645 99.698  1.00 75.80  ? 943  ARG A CA    1 
ATOM   5425  C  C     . ARG A 1 925  ? 153.376 131.825 99.569  1.00 75.80  ? 943  ARG A C     1 
ATOM   5426  O  O     . ARG A 1 925  ? 152.816 131.584 98.494  1.00 75.80  ? 943  ARG A O     1 
ATOM   5427  C  CB    . ARG A 1 925  ? 155.208 130.210 100.114 1.00 75.80  ? 943  ARG A CB    1 
ATOM   5428  C  CG    . ARG A 1 925  ? 154.691 129.161 99.145  1.00 75.80  ? 943  ARG A CG    1 
ATOM   5429  C  CD    . ARG A 1 925  ? 154.849 127.756 99.694  1.00 75.80  ? 943  ARG A CD    1 
ATOM   5430  N  NE    . ARG A 1 925  ? 154.310 126.762 98.774  1.00 75.80  ? 943  ARG A NE    1 
ATOM   5431  C  CZ    . ARG A 1 925  ? 155.010 126.175 97.814  1.00 75.80  ? 943  ARG A CZ    1 
ATOM   5432  N  NH1   . ARG A 1 925  ? 156.291 126.448 97.627  1.00 75.80  ? 943  ARG A NH1   1 
ATOM   5433  N  NH2   . ARG A 1 925  ? 154.410 125.291 97.022  1.00 75.80  ? 943  ARG A NH2   1 
ATOM   5434  N  N     . GLU A 1 926  ? 152.704 132.242 100.644 1.00 78.09  ? 944  GLU A N     1 
ATOM   5435  C  CA    . GLU A 1 926  ? 151.253 132.395 100.594 1.00 78.09  ? 944  GLU A CA    1 
ATOM   5436  C  C     . GLU A 1 926  ? 150.842 133.483 99.609  1.00 78.09  ? 944  GLU A C     1 
ATOM   5437  O  O     . GLU A 1 926  ? 149.878 133.315 98.854  1.00 78.09  ? 944  GLU A O     1 
ATOM   5438  C  CB    . GLU A 1 926  ? 150.705 132.695 101.989 1.00 78.09  ? 944  GLU A CB    1 
ATOM   5439  C  CG    . GLU A 1 926  ? 150.822 131.539 102.975 1.00 78.09  ? 944  GLU A CG    1 
ATOM   5440  C  CD    . GLU A 1 926  ? 152.236 131.338 103.487 1.00 78.09  ? 944  GLU A CD    1 
ATOM   5441  O  OE1   . GLU A 1 926  ? 153.043 132.287 103.396 1.00 78.09  ? 944  GLU A OE1   1 
ATOM   5442  O  OE2   . GLU A 1 926  ? 152.542 130.231 103.977 1.00 78.09  ? 944  GLU A OE2   1 
ATOM   5443  N  N     . HIS A 1 927  ? 151.559 134.609 99.603  1.00 75.08  ? 945  HIS A N     1 
ATOM   5444  C  CA    . HIS A 1 927  ? 151.267 135.668 98.644  1.00 75.08  ? 945  HIS A CA    1 
ATOM   5445  C  C     . HIS A 1 927  ? 151.785 135.332 97.253  1.00 75.08  ? 945  HIS A C     1 
ATOM   5446  O  O     . HIS A 1 927  ? 151.162 135.713 96.253  1.00 75.08  ? 945  HIS A O     1 
ATOM   5447  C  CB    . HIS A 1 927  ? 151.868 136.990 99.121  1.00 75.08  ? 945  HIS A CB    1 
ATOM   5448  C  CG    . HIS A 1 927  ? 151.486 137.358 100.520 1.00 75.08  ? 945  HIS A CG    1 
ATOM   5449  N  ND1   . HIS A 1 927  ? 150.175 137.503 100.920 1.00 75.08  ? 945  HIS A ND1   1 
ATOM   5450  C  CD2   . HIS A 1 927  ? 152.243 137.613 101.613 1.00 75.08  ? 945  HIS A CD2   1 
ATOM   5451  C  CE1   . HIS A 1 927  ? 150.141 137.829 102.199 1.00 75.08  ? 945  HIS A CE1   1 
ATOM   5452  N  NE2   . HIS A 1 927  ? 151.383 137.902 102.644 1.00 75.08  ? 945  HIS A NE2   1 
ATOM   5453  N  N     . ALA A 1 928  ? 152.921 134.634 97.173  1.00 71.40  ? 946  ALA A N     1 
ATOM   5454  C  CA    . ALA A 1 928  ? 153.450 134.222 95.879  1.00 71.40  ? 946  ALA A CA    1 
ATOM   5455  C  C     . ALA A 1 928  ? 152.484 133.291 95.165  1.00 71.40  ? 946  ALA A C     1 
ATOM   5456  O  O     . ALA A 1 928  ? 152.333 133.364 93.943  1.00 71.40  ? 946  ALA A O     1 
ATOM   5457  C  CB    . ALA A 1 928  ? 154.811 133.549 96.055  1.00 71.40  ? 946  ALA A CB    1 
ATOM   5458  N  N     . LYS A 1 929  ? 151.824 132.405 95.911  1.00 71.37  ? 947  LYS A N     1 
ATOM   5459  C  CA    . LYS A 1 929  ? 150.837 131.513 95.312  1.00 71.37  ? 947  LYS A CA    1 
ATOM   5460  C  C     . LYS A 1 929  ? 149.693 132.303 94.691  1.00 71.37  ? 947  LYS A C     1 
ATOM   5461  O  O     . LYS A 1 929  ? 149.289 132.045 93.549  1.00 71.37  ? 947  LYS A O     1 
ATOM   5462  C  CB    . LYS A 1 929  ? 150.311 130.545 96.370  1.00 71.37  ? 947  LYS A CB    1 
ATOM   5463  C  CG    . LYS A 1 929  ? 149.206 129.627 95.885  1.00 71.37  ? 947  LYS A CG    1 
ATOM   5464  C  CD    . LYS A 1 929  ? 148.711 128.737 97.011  1.00 71.37  ? 947  LYS A CD    1 
ATOM   5465  C  CE    . LYS A 1 929  ? 149.867 128.024 97.691  1.00 71.37  ? 947  LYS A CE    1 
ATOM   5466  N  NZ    . LYS A 1 929  ? 149.403 127.117 98.777  1.00 71.37  ? 947  LYS A NZ    1 
ATOM   5467  N  N     . ILE A 1 930  ? 149.162 133.278 95.431  1.00 71.20  ? 948  ILE A N     1 
ATOM   5468  C  CA    . ILE A 1 930  ? 148.064 134.094 94.921  1.00 71.20  ? 948  ILE A CA    1 
ATOM   5469  C  C     . ILE A 1 930  ? 148.503 134.845 93.672  1.00 71.20  ? 948  ILE A C     1 
ATOM   5470  O  O     . ILE A 1 930  ? 147.802 134.855 92.653  1.00 71.20  ? 948  ILE A O     1 
ATOM   5471  C  CB    . ILE A 1 930  ? 147.561 135.057 96.011  1.00 71.20  ? 948  ILE A CB    1 
ATOM   5472  C  CG1   . ILE A 1 930  ? 146.949 134.276 97.176  1.00 71.20  ? 948  ILE A CG1   1 
ATOM   5473  C  CG2   . ILE A 1 930  ? 146.555 136.042 95.435  1.00 71.20  ? 948  ILE A CG2   1 
ATOM   5474  C  CD1   . ILE A 1 930  ? 145.704 133.505 96.806  1.00 71.20  ? 948  ILE A CD1   1 
ATOM   5475  N  N     . PHE A 1 931  ? 149.685 135.467 93.727  1.00 67.24  ? 949  PHE A N     1 
ATOM   5476  C  CA    . PHE A 1 931  ? 150.167 136.221 92.575  1.00 67.24  ? 949  PHE A CA    1 
ATOM   5477  C  C     . PHE A 1 931  ? 150.369 135.322 91.362  1.00 67.24  ? 949  PHE A C     1 
ATOM   5478  O  O     . PHE A 1 931  ? 149.999 135.689 90.241  1.00 67.24  ? 949  PHE A O     1 
ATOM   5479  C  CB    . PHE A 1 931  ? 151.473 136.942 92.904  1.00 67.24  ? 949  PHE A CB    1 
ATOM   5480  C  CG    . PHE A 1 931  ? 152.318 137.198 91.695  1.00 67.24  ? 949  PHE A CG    1 
ATOM   5481  C  CD1   . PHE A 1 931  ? 151.989 138.210 90.811  1.00 67.24  ? 949  PHE A CD1   1 
ATOM   5482  C  CD2   . PHE A 1 931  ? 153.416 136.403 91.419  1.00 67.24  ? 949  PHE A CD2   1 
ATOM   5483  C  CE1   . PHE A 1 931  ? 152.748 138.437 89.684  1.00 67.24  ? 949  PHE A CE1   1 
ATOM   5484  C  CE2   . PHE A 1 931  ? 154.177 136.622 90.293  1.00 67.24  ? 949  PHE A CE2   1 
ATOM   5485  C  CZ    . PHE A 1 931  ? 153.842 137.641 89.423  1.00 67.24  ? 949  PHE A CZ    1 
ATOM   5486  N  N     . ASN A 1 932  ? 150.976 134.150 91.559  1.00 63.27  ? 950  ASN A N     1 
ATOM   5487  C  CA    . ASN A 1 932  ? 151.254 133.260 90.439  1.00 63.27  ? 950  ASN A CA    1 
ATOM   5488  C  C     . ASN A 1 932  ? 149.965 132.758 89.806  1.00 63.27  ? 950  ASN A C     1 
ATOM   5489  O  O     . ASN A 1 932  ? 149.812 132.794 88.579  1.00 63.27  ? 950  ASN A O     1 
ATOM   5490  C  CB    . ASN A 1 932  ? 152.121 132.088 90.899  1.00 63.27  ? 950  ASN A CB    1 
ATOM   5491  C  CG    . ASN A 1 932  ? 153.560 132.491 91.144  1.00 63.27  ? 950  ASN A CG    1 
ATOM   5492  O  OD1   . ASN A 1 932  ? 154.069 133.425 90.525  1.00 63.27  ? 950  ASN A OD1   1 
ATOM   5493  N  ND2   . ASN A 1 932  ? 154.226 131.785 92.047  1.00 63.27  ? 950  ASN A ND2   1 
ATOM   5494  N  N     . TYR A 1 933  ? 149.021 132.290 90.625  1.00 62.52  ? 951  TYR A N     1 
ATOM   5495  C  CA    . TYR A 1 933  ? 147.760 131.813 90.070  1.00 62.52  ? 951  TYR A CA    1 
ATOM   5496  C  C     . TYR A 1 933  ? 146.973 132.939 89.410  1.00 62.52  ? 951  TYR A C     1 
ATOM   5497  O  O     . TYR A 1 933  ? 146.235 132.690 88.451  1.00 62.52  ? 951  TYR A O     1 
ATOM   5498  C  CB    . TYR A 1 933  ? 146.928 131.131 91.153  1.00 62.52  ? 951  TYR A CB    1 
ATOM   5499  C  CG    . TYR A 1 933  ? 147.346 129.704 91.434  1.00 62.52  ? 951  TYR A CG    1 
ATOM   5500  C  CD1   . TYR A 1 933  ? 148.459 129.426 92.216  1.00 62.52  ? 951  TYR A CD1   1 
ATOM   5501  C  CD2   . TYR A 1 933  ? 146.625 128.634 90.918  1.00 62.52  ? 951  TYR A CD2   1 
ATOM   5502  C  CE1   . TYR A 1 933  ? 148.844 128.126 92.475  1.00 62.52  ? 951  TYR A CE1   1 
ATOM   5503  C  CE2   . TYR A 1 933  ? 147.002 127.329 91.172  1.00 62.52  ? 951  TYR A CE2   1 
ATOM   5504  C  CZ    . TYR A 1 933  ? 148.112 127.082 91.951  1.00 62.52  ? 951  TYR A CZ    1 
ATOM   5505  O  OH    . TYR A 1 933  ? 148.494 125.787 92.209  1.00 62.52  ? 951  TYR A OH    1 
ATOM   5506  N  N     . GLY A 1 934  ? 147.113 134.174 89.895  1.00 60.39  ? 952  GLY A N     1 
ATOM   5507  C  CA    . GLY A 1 934  ? 146.502 135.297 89.202  1.00 60.39  ? 952  GLY A CA    1 
ATOM   5508  C  C     . GLY A 1 934  ? 147.154 135.576 87.861  1.00 60.39  ? 952  GLY A C     1 
ATOM   5509  O  O     . GLY A 1 934  ? 146.473 135.898 86.884  1.00 60.39  ? 952  GLY A O     1 
ATOM   5510  N  N     . ARG A 1 935  ? 148.483 135.465 87.801  1.00 55.61  ? 953  ARG A N     1 
ATOM   5511  C  CA    . ARG A 1 935  ? 149.198 135.668 86.545  1.00 55.61  ? 953  ARG A CA    1 
ATOM   5512  C  C     . ARG A 1 935  ? 148.825 134.607 85.518  1.00 55.61  ? 953  ARG A C     1 
ATOM   5513  O  O     . ARG A 1 935  ? 148.697 134.906 84.325  1.00 55.61  ? 953  ARG A O     1 
ATOM   5514  C  CB    . ARG A 1 935  ? 150.704 135.674 86.802  1.00 55.61  ? 953  ARG A CB    1 
ATOM   5515  C  CG    . ARG A 1 935  ? 151.550 135.337 85.590  1.00 55.61  ? 953  ARG A CG    1 
ATOM   5516  C  CD    . ARG A 1 935  ? 152.967 135.853 85.749  1.00 55.61  ? 953  ARG A CD    1 
ATOM   5517  N  NE    . ARG A 1 935  ? 153.571 135.429 87.005  1.00 55.61  ? 953  ARG A NE    1 
ATOM   5518  C  CZ    . ARG A 1 935  ? 154.275 134.317 87.159  1.00 55.61  ? 953  ARG A CZ    1 
ATOM   5519  N  NH1   . ARG A 1 935  ? 154.476 133.482 86.154  1.00 55.61  ? 953  ARG A NH1   1 
ATOM   5520  N  NH2   . ARG A 1 935  ? 154.792 134.036 88.352  1.00 55.61  ? 953  ARG A NH2   1 
ATOM   5521  N  N     . ILE A 1 936  ? 148.640 133.361 85.964  1.00 49.48  ? 954  ILE A N     1 
ATOM   5522  C  CA    . ILE A 1 936  ? 148.208 132.298 85.059  1.00 49.48  ? 954  ILE A CA    1 
ATOM   5523  C  C     . ILE A 1 936  ? 146.853 132.632 84.446  1.00 49.48  ? 954  ILE A C     1 
ATOM   5524  O  O     . ILE A 1 936  ? 146.533 132.183 83.338  1.00 49.48  ? 954  ILE A O     1 
ATOM   5525  C  CB    . ILE A 1 936  ? 148.183 130.944 85.802  1.00 49.48  ? 954  ILE A CB    1 
ATOM   5526  C  CG1   . ILE A 1 936  ? 149.555 130.635 86.402  1.00 49.48  ? 954  ILE A CG1   1 
ATOM   5527  C  CG2   . ILE A 1 936  ? 147.765 129.815 84.876  1.00 49.48  ? 954  ILE A CG2   1 
ATOM   5528  C  CD1   . ILE A 1 936  ? 150.692 130.703 85.411  1.00 49.48  ? 954  ILE A CD1   1 
ATOM   5529  N  N     . TYR A 1 937  ? 146.051 133.445 85.132  1.00 46.72  ? 955  TYR A N     1 
ATOM   5530  C  CA    . TYR A 1 937  ? 144.726 133.830 84.664  1.00 46.72  ? 955  TYR A CA    1 
ATOM   5531  C  C     . TYR A 1 937  ? 144.750 135.048 83.751  1.00 46.72  ? 955  TYR A C     1 
ATOM   5532  O  O     . TYR A 1 937  ? 143.685 135.568 83.406  1.00 46.72  ? 955  TYR A O     1 
ATOM   5533  C  CB    . TYR A 1 937  ? 143.807 134.102 85.857  1.00 46.72  ? 955  TYR A CB    1 
ATOM   5534  C  CG    . TYR A 1 937  ? 143.576 132.893 86.727  1.00 46.72  ? 955  TYR A CG    1 
ATOM   5535  C  CD1   . TYR A 1 937  ? 143.696 131.614 86.208  1.00 46.72  ? 955  TYR A CD1   1 
ATOM   5536  C  CD2   . TYR A 1 937  ? 143.241 133.028 88.065  1.00 46.72  ? 955  TYR A CD2   1 
ATOM   5537  C  CE1   . TYR A 1 937  ? 143.489 130.506 86.994  1.00 46.72  ? 955  TYR A CE1   1 
ATOM   5538  C  CE2   . TYR A 1 937  ? 143.033 131.922 88.862  1.00 46.72  ? 955  TYR A CE2   1 
ATOM   5539  C  CZ    . TYR A 1 937  ? 143.159 130.663 88.320  1.00 46.72  ? 955  TYR A CZ    1 
ATOM   5540  O  OH    . TYR A 1 937  ? 142.951 129.555 89.109  1.00 46.72  ? 955  TYR A OH    1 
ATOM   5541  N  N     . GLY A 1 938  ? 145.930 135.517 83.359  1.00 47.67  ? 956  GLY A N     1 
ATOM   5542  C  CA    . GLY A 1 938  ? 146.022 136.652 82.467  1.00 47.67  ? 956  GLY A CA    1 
ATOM   5543  C  C     . GLY A 1 938  ? 145.858 138.001 83.123  1.00 47.67  ? 956  GLY A C     1 
ATOM   5544  O  O     . GLY A 1 938  ? 145.669 138.995 82.414  1.00 47.67  ? 956  GLY A O     1 
ATOM   5545  N  N     . ALA A 1 939  ? 145.912 138.070 84.451  1.00 50.23  ? 957  ALA A N     1 
ATOM   5546  C  CA    . ALA A 1 939  ? 145.846 139.354 85.132  1.00 50.23  ? 957  ALA A CA    1 
ATOM   5547  C  C     . ALA A 1 939  ? 147.033 140.217 84.730  1.00 50.23  ? 957  ALA A C     1 
ATOM   5548  O  O     . ALA A 1 939  ? 148.184 139.773 84.770  1.00 50.23  ? 957  ALA A O     1 
ATOM   5549  C  CB    . ALA A 1 939  ? 145.820 139.148 86.646  1.00 50.23  ? 957  ALA A CB    1 
ATOM   5550  N  N     . GLY A 1 940  ? 146.751 141.456 84.346  1.00 51.36  ? 958  GLY A N     1 
ATOM   5551  C  CA    . GLY A 1 940  ? 147.773 142.310 83.783  1.00 51.36  ? 958  GLY A CA    1 
ATOM   5552  C  C     . GLY A 1 940  ? 148.763 142.806 84.817  1.00 51.36  ? 958  GLY A C     1 
ATOM   5553  O  O     . GLY A 1 940  ? 148.635 142.582 86.021  1.00 51.36  ? 958  GLY A O     1 
ATOM   5554  N  N     . GLN A 1 941  ? 149.791 143.488 84.314  1.00 58.58  ? 959  GLN A N     1 
ATOM   5555  C  CA    . GLN A 1 941  ? 150.790 144.080 85.198  1.00 58.58  ? 959  GLN A CA    1 
ATOM   5556  C  C     . GLN A 1 941  ? 150.208 145.065 86.206  1.00 58.58  ? 959  GLN A C     1 
ATOM   5557  O  O     . GLN A 1 941  ? 150.643 145.030 87.369  1.00 58.58  ? 959  GLN A O     1 
ATOM   5558  C  CB    . GLN A 1 941  ? 151.896 144.742 84.367  1.00 58.58  ? 959  GLN A CB    1 
ATOM   5559  C  CG    . GLN A 1 941  ? 152.800 143.760 83.647  1.00 58.58  ? 959  GLN A CG    1 
ATOM   5560  C  CD    . GLN A 1 941  ? 154.082 144.403 83.161  1.00 58.58  ? 959  GLN A CD    1 
ATOM   5561  O  OE1   . GLN A 1 941  ? 154.302 145.598 83.355  1.00 58.58  ? 959  GLN A OE1   1 
ATOM   5562  N  NE2   . GLN A 1 941  ? 154.939 143.611 82.528  1.00 58.58  ? 959  GLN A NE2   1 
ATOM   5563  N  N     . PRO A 1 942  ? 149.274 145.964 85.853  1.00 60.09  ? 960  PRO A N     1 
ATOM   5564  C  CA    . PRO A 1 942  ? 148.700 146.841 86.890  1.00 60.09  ? 960  PRO A CA    1 
ATOM   5565  C  C     . PRO A 1 942  ? 148.078 146.080 88.047  1.00 60.09  ? 960  PRO A C     1 
ATOM   5566  O  O     . PRO A 1 942  ? 148.167 146.527 89.199  1.00 60.09  ? 960  PRO A O     1 
ATOM   5567  C  CB    . PRO A 1 942  ? 147.653 147.652 86.115  1.00 60.09  ? 960  PRO A CB    1 
ATOM   5568  C  CG    . PRO A 1 942  ? 148.168 147.686 84.730  1.00 60.09  ? 960  PRO A CG    1 
ATOM   5569  C  CD    . PRO A 1 942  ? 148.811 146.350 84.506  1.00 60.09  ? 960  PRO A CD    1 
ATOM   5570  N  N     . PHE A 1 943  ? 147.447 144.937 87.770  1.00 62.74  ? 961  PHE A N     1 
ATOM   5571  C  CA    . PHE A 1 943  ? 146.927 144.102 88.848  1.00 62.74  ? 961  PHE A CA    1 
ATOM   5572  C  C     . PHE A 1 943  ? 148.049 143.647 89.771  1.00 62.74  ? 961  PHE A C     1 
ATOM   5573  O  O     . PHE A 1 943  ? 147.901 143.670 90.997  1.00 62.74  ? 961  PHE A O     1 
ATOM   5574  C  CB    . PHE A 1 943  ? 146.183 142.899 88.266  1.00 62.74  ? 961  PHE A CB    1 
ATOM   5575  C  CG    . PHE A 1 943  ? 145.720 141.908 89.300  1.00 62.74  ? 961  PHE A CG    1 
ATOM   5576  C  CD1   . PHE A 1 943  ? 144.489 142.054 89.915  1.00 62.74  ? 961  PHE A CD1   1 
ATOM   5577  C  CD2   . PHE A 1 943  ? 146.513 140.826 89.650  1.00 62.74  ? 961  PHE A CD2   1 
ATOM   5578  C  CE1   . PHE A 1 943  ? 144.060 141.144 90.863  1.00 62.74  ? 961  PHE A CE1   1 
ATOM   5579  C  CE2   . PHE A 1 943  ? 146.090 139.915 90.597  1.00 62.74  ? 961  PHE A CE2   1 
ATOM   5580  C  CZ    . PHE A 1 943  ? 144.862 140.074 91.203  1.00 62.74  ? 961  PHE A CZ    1 
ATOM   5581  N  N     . ALA A 1 944  ? 149.182 143.235 89.198  1.00 59.50  ? 962  ALA A N     1 
ATOM   5582  C  CA    . ALA A 1 944  ? 150.313 142.811 90.015  1.00 59.50  ? 962  ALA A CA    1 
ATOM   5583  C  C     . ALA A 1 944  ? 150.863 143.966 90.839  1.00 59.50  ? 962  ALA A C     1 
ATOM   5584  O  O     . ALA A 1 944  ? 151.232 143.785 92.004  1.00 59.50  ? 962  ALA A O     1 
ATOM   5585  C  CB    . ALA A 1 944  ? 151.405 142.212 89.131  1.00 59.50  ? 962  ALA A CB    1 
ATOM   5586  N  N     . GLU A 1 945  ? 150.934 145.161 90.248  1.00 64.14  ? 963  GLU A N     1 
ATOM   5587  C  CA    . GLU A 1 945  ? 151.427 146.327 90.976  1.00 64.14  ? 963  GLU A CA    1 
ATOM   5588  C  C     . GLU A 1 945  ? 150.527 146.649 92.162  1.00 64.14  ? 963  GLU A C     1 
ATOM   5589  O  O     . GLU A 1 945  ? 151.004 146.871 93.284  1.00 64.14  ? 963  GLU A O     1 
ATOM   5590  C  CB    . GLU A 1 945  ? 151.517 147.527 90.034  1.00 64.14  ? 963  GLU A CB    1 
ATOM   5591  C  CG    . GLU A 1 945  ? 152.282 147.251 88.755  1.00 64.14  ? 963  GLU A CG    1 
ATOM   5592  C  CD    . GLU A 1 945  ? 151.913 148.204 87.636  1.00 64.14  ? 963  GLU A CD    1 
ATOM   5593  O  OE1   . GLU A 1 945  ? 151.294 149.250 87.923  1.00 64.14  ? 963  GLU A OE1   1 
ATOM   5594  O  OE2   . GLU A 1 945  ? 152.236 147.902 86.468  1.00 64.14  ? 963  GLU A OE2   1 
ATOM   5595  N  N     . ARG A 1 946  ? 149.213 146.664 91.931  1.00 68.62  ? 964  ARG A N     1 
ATOM   5596  C  CA    . ARG A 1 946  ? 148.275 146.946 93.012  1.00 68.62  ? 964  ARG A CA    1 
ATOM   5597  C  C     . ARG A 1 946  ? 148.325 145.863 94.082  1.00 68.62  ? 964  ARG A C     1 
ATOM   5598  O  O     . ARG A 1 946  ? 148.250 146.161 95.278  1.00 68.62  ? 964  ARG A O     1 
ATOM   5599  C  CB    . ARG A 1 946  ? 146.860 147.093 92.455  1.00 68.62  ? 964  ARG A CB    1 
ATOM   5600  C  CG    . ARG A 1 946  ? 145.816 147.421 93.508  1.00 68.62  ? 964  ARG A CG    1 
ATOM   5601  C  CD    . ARG A 1 946  ? 144.454 147.690 92.889  1.00 68.62  ? 964  ARG A CD    1 
ATOM   5602  N  NE    . ARG A 1 946  ? 143.958 146.548 92.130  1.00 68.62  ? 964  ARG A NE    1 
ATOM   5603  C  CZ    . ARG A 1 946  ? 143.968 146.467 90.807  1.00 68.62  ? 964  ARG A CZ    1 
ATOM   5604  N  NH1   . ARG A 1 946  ? 144.436 147.451 90.058  1.00 68.62  ? 964  ARG A NH1   1 
ATOM   5605  N  NH2   . ARG A 1 946  ? 143.494 145.371 90.221  1.00 68.62  ? 964  ARG A NH2   1 
ATOM   5606  N  N     . LEU A 1 947  ? 148.454 144.599 93.673  1.00 66.59  ? 965  LEU A N     1 
ATOM   5607  C  CA    . LEU A 1 947  ? 148.516 143.511 94.642  1.00 66.59  ? 965  LEU A CA    1 
ATOM   5608  C  C     . LEU A 1 947  ? 149.790 143.579 95.476  1.00 66.59  ? 965  LEU A C     1 
ATOM   5609  O  O     . LEU A 1 947  ? 149.767 143.290 96.677  1.00 66.59  ? 965  LEU A O     1 
ATOM   5610  C  CB    . LEU A 1 947  ? 148.413 142.168 93.922  1.00 66.59  ? 965  LEU A CB    1 
ATOM   5611  C  CG    . LEU A 1 947  ? 147.934 140.991 94.768  1.00 66.59  ? 965  LEU A CG    1 
ATOM   5612  C  CD1   . LEU A 1 947  ? 146.540 141.266 95.307  1.00 66.59  ? 965  LEU A CD1   1 
ATOM   5613  C  CD2   . LEU A 1 947  ? 147.954 139.710 93.956  1.00 66.59  ? 965  LEU A CD2   1 
ATOM   5614  N  N     . LEU A 1 948  ? 150.914 143.941 94.854  1.00 62.85  ? 966  LEU A N     1 
ATOM   5615  C  CA    . LEU A 1 948  ? 152.157 144.092 95.602  1.00 62.85  ? 966  LEU A CA    1 
ATOM   5616  C  C     . LEU A 1 948  ? 152.081 145.270 96.563  1.00 62.85  ? 966  LEU A C     1 
ATOM   5617  O  O     . LEU A 1 948  ? 152.641 145.215 97.664  1.00 62.85  ? 966  LEU A O     1 
ATOM   5618  C  CB    . LEU A 1 948  ? 153.335 144.256 94.642  1.00 62.85  ? 966  LEU A CB    1 
ATOM   5619  C  CG    . LEU A 1 948  ? 154.209 143.017 94.436  1.00 62.85  ? 966  LEU A CG    1 
ATOM   5620  C  CD1   . LEU A 1 948  ? 153.365 141.823 94.026  1.00 62.85  ? 966  LEU A CD1   1 
ATOM   5621  C  CD2   . LEU A 1 948  ? 155.284 143.293 93.402  1.00 62.85  ? 966  LEU A CD2   1 
ATOM   5622  N  N     . MET A 1 949  ? 151.407 146.350 96.161  1.00 67.54  ? 967  MET A N     1 
ATOM   5623  C  CA    . MET A 1 949  ? 151.179 147.451 97.093  1.00 67.54  ? 967  MET A CA    1 
ATOM   5624  C  C     . MET A 1 949  ? 150.292 147.013 98.254  1.00 67.54  ? 967  MET A C     1 
ATOM   5625  O  O     . MET A 1 949  ? 150.534 147.388 99.407  1.00 67.54  ? 967  MET A O     1 
ATOM   5626  C  CB    . MET A 1 949  ? 150.559 148.644 96.365  1.00 67.54  ? 967  MET A CB    1 
ATOM   5627  C  CG    . MET A 1 949  ? 151.508 149.348 95.412  1.00 67.54  ? 967  MET A CG    1 
ATOM   5628  S  SD    . MET A 1 949  ? 150.832 150.875 94.734  1.00 67.54  ? 967  MET A SD    1 
ATOM   5629  C  CE    . MET A 1 949  ? 150.661 151.859 96.220  1.00 67.54  ? 967  MET A CE    1 
ATOM   5630  N  N     . GLN A 1 950  ? 149.260 146.219 97.965  1.00 68.62  ? 968  GLN A N     1 
ATOM   5631  C  CA    . GLN A 1 950  ? 148.319 145.797 98.997  1.00 68.62  ? 968  GLN A CA    1 
ATOM   5632  C  C     . GLN A 1 950  ? 148.973 144.859 100.005 1.00 68.62  ? 968  GLN A C     1 
ATOM   5633  O  O     . GLN A 1 950  ? 148.853 145.058 101.219 1.00 68.62  ? 968  GLN A O     1 
ATOM   5634  C  CB    . GLN A 1 950  ? 147.109 145.128 98.344  1.00 68.62  ? 968  GLN A CB    1 
ATOM   5635  C  CG    . GLN A 1 950  ? 146.221 144.359 99.301  1.00 68.62  ? 968  GLN A CG    1 
ATOM   5636  C  CD    . GLN A 1 950  ? 145.042 143.715 98.600  1.00 68.62  ? 968  GLN A CD    1 
ATOM   5637  O  OE1   . GLN A 1 950  ? 144.608 144.173 97.543  1.00 68.62  ? 968  GLN A OE1   1 
ATOM   5638  N  NE2   . GLN A 1 950  ? 144.519 142.643 99.183  1.00 68.62  ? 968  GLN A NE2   1 
ATOM   5639  N  N     . PHE A 1 951  ? 149.667 143.826 99.520  1.00 69.01  ? 969  PHE A N     1 
ATOM   5640  C  CA    . PHE A 1 951  ? 150.295 142.869 100.426 1.00 69.01  ? 969  PHE A CA    1 
ATOM   5641  C  C     . PHE A 1 951  ? 151.373 143.533 101.269 1.00 69.01  ? 969  PHE A C     1 
ATOM   5642  O  O     . PHE A 1 951  ? 151.492 143.259 102.469 1.00 69.01  ? 969  PHE A O     1 
ATOM   5643  C  CB    . PHE A 1 951  ? 150.883 141.700 99.636  1.00 69.01  ? 969  PHE A CB    1 
ATOM   5644  C  CG    . PHE A 1 951  ? 149.850 140.795 99.034  1.00 69.01  ? 969  PHE A CG    1 
ATOM   5645  C  CD1   . PHE A 1 951  ? 148.545 140.804 99.497  1.00 69.01  ? 969  PHE A CD1   1 
ATOM   5646  C  CD2   . PHE A 1 951  ? 150.186 139.931 98.007  1.00 69.01  ? 969  PHE A CD2   1 
ATOM   5647  C  CE1   . PHE A 1 951  ? 147.593 139.970 98.944  1.00 69.01  ? 969  PHE A CE1   1 
ATOM   5648  C  CE2   . PHE A 1 951  ? 149.239 139.093 97.451  1.00 69.01  ? 969  PHE A CE2   1 
ATOM   5649  C  CZ    . PHE A 1 951  ? 147.941 139.114 97.920  1.00 69.01  ? 969  PHE A CZ    1 
ATOM   5650  N  N     . ASN A 1 952  ? 152.170 144.405 100.661 1.00 63.33  ? 970  ASN A N     1 
ATOM   5651  C  CA    . ASN A 1 952  ? 153.238 145.117 101.357 1.00 63.33  ? 970  ASN A CA    1 
ATOM   5652  C  C     . ASN A 1 952  ? 153.029 146.606 101.101 1.00 63.33  ? 970  ASN A C     1 
ATOM   5653  O  O     . ASN A 1 952  ? 153.439 147.126 100.060 1.00 63.33  ? 970  ASN A O     1 
ATOM   5654  C  CB    . ASN A 1 952  ? 154.611 144.651 100.883 1.00 63.33  ? 970  ASN A CB    1 
ATOM   5655  C  CG    . ASN A 1 952  ? 155.728 145.095 101.806 1.00 63.33  ? 970  ASN A CG    1 
ATOM   5656  O  OD1   . ASN A 1 952  ? 155.582 146.055 102.558 1.00 63.33  ? 970  ASN A OD1   1 
ATOM   5657  N  ND2   . ASN A 1 952  ? 156.854 144.394 101.750 1.00 63.33  ? 970  ASN A ND2   1 
ATOM   5658  N  N     . HIS A 1 953  ? 152.388 147.288 102.053 1.00 65.04  ? 971  HIS A N     1 
ATOM   5659  C  CA    . HIS A 1 953  ? 152.115 148.712 101.903 1.00 65.04  ? 971  HIS A CA    1 
ATOM   5660  C  C     . HIS A 1 953  ? 153.378 149.561 101.917 1.00 65.04  ? 971  HIS A C     1 
ATOM   5661  O  O     . HIS A 1 953  ? 153.314 150.737 101.544 1.00 65.04  ? 971  HIS A O     1 
ATOM   5662  C  CB    . HIS A 1 953  ? 151.153 149.185 102.995 1.00 65.04  ? 971  HIS A CB    1 
ATOM   5663  C  CG    . HIS A 1 953  ? 151.311 148.466 104.299 1.00 65.04  ? 971  HIS A CG    1 
ATOM   5664  N  ND1   . HIS A 1 953  ? 150.493 147.424 104.677 1.00 65.04  ? 971  HIS A ND1   1 
ATOM   5665  C  CD2   . HIS A 1 953  ? 152.189 148.643 105.314 1.00 65.04  ? 971  HIS A CD2   1 
ATOM   5666  C  CE1   . HIS A 1 953  ? 150.861 146.988 105.869 1.00 65.04  ? 971  HIS A CE1   1 
ATOM   5667  N  NE2   . HIS A 1 953  ? 151.888 147.711 106.277 1.00 65.04  ? 971  HIS A NE2   1 
ATOM   5668  N  N     . ARG A 1 954  ? 154.516 149.002 102.331 1.00 65.30  ? 972  ARG A N     1 
ATOM   5669  C  CA    . ARG A 1 954  ? 155.778 149.723 102.232 1.00 65.30  ? 972  ARG A CA    1 
ATOM   5670  C  C     . ARG A 1 954  ? 156.245 149.883 100.791 1.00 65.30  ? 972  ARG A C     1 
ATOM   5671  O  O     . ARG A 1 954  ? 157.169 150.664 100.541 1.00 65.30  ? 972  ARG A O     1 
ATOM   5672  C  CB    . ARG A 1 954  ? 156.860 149.009 103.044 1.00 65.30  ? 972  ARG A CB    1 
ATOM   5673  C  CG    . ARG A 1 954  ? 156.409 148.540 104.418 1.00 65.30  ? 972  ARG A CG    1 
ATOM   5674  C  CD    . ARG A 1 954  ? 155.916 149.688 105.278 1.00 65.30  ? 972  ARG A CD    1 
ATOM   5675  N  NE    . ARG A 1 954  ? 155.638 149.253 106.641 1.00 65.30  ? 972  ARG A NE    1 
ATOM   5676  C  CZ    . ARG A 1 954  ? 156.530 149.254 107.622 1.00 65.30  ? 972  ARG A CZ    1 
ATOM   5677  N  NH1   . ARG A 1 954  ? 157.769 149.675 107.428 1.00 65.30  ? 972  ARG A NH1   1 
ATOM   5678  N  NH2   . ARG A 1 954  ? 156.171 148.820 108.826 1.00 65.30  ? 972  ARG A NH2   1 
ATOM   5679  N  N     . LEU A 1 955  ? 155.633 149.169 99.848  1.00 68.54  ? 973  LEU A N     1 
ATOM   5680  C  CA    . LEU A 1 955  ? 155.985 149.264 98.438  1.00 68.54  ? 973  LEU A CA    1 
ATOM   5681  C  C     . LEU A 1 955  ? 155.212 150.415 97.806  1.00 68.54  ? 973  LEU A C     1 
ATOM   5682  O  O     . LEU A 1 955  ? 153.976 150.429 97.835  1.00 68.54  ? 973  LEU A O     1 
ATOM   5683  C  CB    . LEU A 1 955  ? 155.679 147.954 97.712  1.00 68.54  ? 973  LEU A CB    1 
ATOM   5684  C  CG    . LEU A 1 955  ? 156.788 146.902 97.617  1.00 68.54  ? 973  LEU A CG    1 
ATOM   5685  C  CD1   . LEU A 1 955  ? 157.295 146.497 98.992  1.00 68.54  ? 973  LEU A CD1   1 
ATOM   5686  C  CD2   . LEU A 1 955  ? 156.293 145.687 96.847  1.00 68.54  ? 973  LEU A CD2   1 
ATOM   5687  N  N     . THR A 1 956  ? 155.938 151.373 97.235  1.00 78.59  ? 974  THR A N     1 
ATOM   5688  C  CA    . THR A 1 956  ? 155.307 152.520 96.603  1.00 78.59  ? 974  THR A CA    1 
ATOM   5689  C  C     . THR A 1 956  ? 154.710 152.115 95.256  1.00 78.59  ? 974  THR A C     1 
ATOM   5690  O  O     . THR A 1 956  ? 154.730 150.948 94.858  1.00 78.59  ? 974  THR A O     1 
ATOM   5691  C  CB    . THR A 1 956  ? 156.315 153.654 96.433  1.00 78.59  ? 974  THR A CB    1 
ATOM   5692  O  OG1   . THR A 1 956  ? 157.302 153.277 95.465  1.00 78.59  ? 974  THR A OG1   1 
ATOM   5693  C  CG2   . THR A 1 956  ? 157.002 153.952 97.756  1.00 78.59  ? 974  THR A CG2   1 
ATOM   5694  N  N     . GLN A 1 957  ? 154.163 153.101 94.545  1.00 78.62  ? 975  GLN A N     1 
ATOM   5695  C  CA    . GLN A 1 957  ? 153.587 152.828 93.232  1.00 78.62  ? 975  GLN A CA    1 
ATOM   5696  C  C     . GLN A 1 957  ? 154.677 152.527 92.210  1.00 78.62  ? 975  GLN A C     1 
ATOM   5697  O  O     . GLN A 1 957  ? 154.577 151.561 91.445  1.00 78.62  ? 975  GLN A O     1 
ATOM   5698  C  CB    . GLN A 1 957  ? 152.728 154.012 92.783  1.00 78.62  ? 975  GLN A CB    1 
ATOM   5699  C  CG    . GLN A 1 957  ? 151.635 153.658 91.783  1.00 78.62  ? 975  GLN A CG    1 
ATOM   5700  C  CD    . GLN A 1 957  ? 152.170 153.384 90.392  1.00 78.62  ? 975  GLN A CD    1 
ATOM   5701  O  OE1   . GLN A 1 957  ? 153.168 153.970 89.972  1.00 78.62  ? 975  GLN A OE1   1 
ATOM   5702  N  NE2   . GLN A 1 957  ? 151.510 152.487 89.670  1.00 78.62  ? 975  GLN A NE2   1 
ATOM   5703  N  N     . GLN A 1 958  ? 155.732 153.345 92.187  1.00 81.82  ? 976  GLN A N     1 
ATOM   5704  C  CA    . GLN A 1 958  ? 156.810 153.143 91.224  1.00 81.82  ? 976  GLN A CA    1 
ATOM   5705  C  C     . GLN A 1 958  ? 157.574 151.854 91.504  1.00 81.82  ? 976  GLN A C     1 
ATOM   5706  O  O     . GLN A 1 958  ? 157.907 151.109 90.574  1.00 81.82  ? 976  GLN A O     1 
ATOM   5707  C  CB    . GLN A 1 958  ? 157.752 154.348 91.239  1.00 81.82  ? 976  GLN A CB    1 
ATOM   5708  C  CG    . GLN A 1 958  ? 158.859 154.304 90.196  1.00 81.82  ? 976  GLN A CG    1 
ATOM   5709  C  CD    . GLN A 1 958  ? 160.111 153.607 90.695  1.00 81.82  ? 976  GLN A CD    1 
ATOM   5710  O  OE1   . GLN A 1 958  ? 160.231 153.292 91.879  1.00 81.82  ? 976  GLN A OE1   1 
ATOM   5711  N  NE2   . GLN A 1 958  ? 161.051 153.363 89.790  1.00 81.82  ? 976  GLN A NE2   1 
ATOM   5712  N  N     . GLU A 1 959  ? 157.872 151.578 92.776  1.00 81.07  ? 977  GLU A N     1 
ATOM   5713  C  CA    . GLU A 1 959  ? 158.593 150.354 93.113  1.00 81.07  ? 977  GLU A CA    1 
ATOM   5714  C  C     . GLU A 1 959  ? 157.762 149.118 92.793  1.00 81.07  ? 977  GLU A C     1 
ATOM   5715  O  O     . GLU A 1 959  ? 158.289 148.121 92.287  1.00 81.07  ? 977  GLU A O     1 
ATOM   5716  C  CB    . GLU A 1 959  ? 158.997 150.366 94.587  1.00 81.07  ? 977  GLU A CB    1 
ATOM   5717  C  CG    . GLU A 1 959  ? 159.973 151.475 94.966  1.00 81.07  ? 977  GLU A CG    1 
ATOM   5718  C  CD    . GLU A 1 959  ? 161.384 151.236 94.452  1.00 81.07  ? 977  GLU A CD    1 
ATOM   5719  O  OE1   . GLU A 1 959  ? 161.647 150.158 93.876  1.00 81.07  ? 977  GLU A OE1   1 
ATOM   5720  O  OE2   . GLU A 1 959  ? 162.237 152.130 94.632  1.00 81.07  ? 977  GLU A OE2   1 
ATOM   5721  N  N     . ALA A 1 960  ? 156.458 149.164 93.081  1.00 71.28  ? 978  ALA A N     1 
ATOM   5722  C  CA    . ALA A 1 960  ? 155.592 148.043 92.734  1.00 71.28  ? 978  ALA A CA    1 
ATOM   5723  C  C     . ALA A 1 960  ? 155.506 147.862 91.226  1.00 71.28  ? 978  ALA A C     1 
ATOM   5724  O  O     . ALA A 1 960  ? 155.483 146.730 90.732  1.00 71.28  ? 978  ALA A O     1 
ATOM   5725  C  CB    . ALA A 1 960  ? 154.199 148.242 93.327  1.00 71.28  ? 978  ALA A CB    1 
ATOM   5726  N  N     . ALA A 1 961  ? 155.448 148.966 90.478  1.00 67.26  ? 979  ALA A N     1 
ATOM   5727  C  CA    . ALA A 1 961  ? 155.429 148.872 89.022  1.00 67.26  ? 979  ALA A CA    1 
ATOM   5728  C  C     . ALA A 1 961  ? 156.701 148.217 88.500  1.00 67.26  ? 979  ALA A C     1 
ATOM   5729  O  O     . ALA A 1 961  ? 156.649 147.327 87.644  1.00 67.26  ? 979  ALA A O     1 
ATOM   5730  C  CB    . ALA A 1 961  ? 155.242 150.260 88.410  1.00 67.26  ? 979  ALA A CB    1 
ATOM   5731  N  N     . GLU A 1 962  ? 157.856 148.642 89.018  1.00 67.42  ? 980  GLU A N     1 
ATOM   5732  C  CA    . GLU A 1 962  ? 159.122 148.043 88.605  1.00 67.42  ? 980  GLU A CA    1 
ATOM   5733  C  C     . GLU A 1 962  ? 159.171 146.559 88.947  1.00 67.42  ? 980  GLU A C     1 
ATOM   5734  O  O     . GLU A 1 962  ? 159.580 145.733 88.118  1.00 67.42  ? 980  GLU A O     1 
ATOM   5735  C  CB    . GLU A 1 962  ? 160.285 148.784 89.268  1.00 67.42  ? 980  GLU A CB    1 
ATOM   5736  C  CG    . GLU A 1 962  ? 161.604 148.024 89.265  1.00 67.42  ? 980  GLU A CG    1 
ATOM   5737  C  CD    . GLU A 1 962  ? 162.263 147.989 87.900  1.00 67.42  ? 980  GLU A CD    1 
ATOM   5738  O  OE1   . GLU A 1 962  ? 161.876 148.793 87.027  1.00 67.42  ? 980  GLU A OE1   1 
ATOM   5739  O  OE2   . GLU A 1 962  ? 163.172 147.156 87.703  1.00 67.42  ? 980  GLU A OE2   1 
ATOM   5740  N  N     . LYS A 1 963  ? 158.756 146.213 90.155  1.00 68.62  ? 981  LYS A N     1 
ATOM   5741  C  CA    . LYS A 1 963  ? 158.769 144.819 90.570  1.00 68.62  ? 981  LYS A CA    1 
ATOM   5742  C  C     . LYS A 1 963  ? 157.896 143.991 89.656  1.00 68.62  ? 981  LYS A C     1 
ATOM   5743  O  O     . LYS A 1 963  ? 158.333 142.971 89.131  1.00 68.62  ? 981  LYS A O     1 
ATOM   5744  C  CB    . LYS A 1 963  ? 158.273 144.690 92.007  1.00 68.62  ? 981  LYS A CB    1 
ATOM   5745  C  CG    . LYS A 1 963  ? 159.138 143.806 92.888  1.00 68.62  ? 981  LYS A CG    1 
ATOM   5746  C  CD    . LYS A 1 963  ? 158.684 143.870 94.336  1.00 68.62  ? 981  LYS A CD    1 
ATOM   5747  C  CE    . LYS A 1 963  ? 159.680 143.184 95.255  1.00 68.62  ? 981  LYS A CE    1 
ATOM   5748  N  NZ    . LYS A 1 963  ? 159.232 143.207 96.674  1.00 68.62  ? 981  LYS A NZ    1 
ATOM   5749  N  N     . ALA A 1 964  ? 156.660 144.426 89.459  1.00 64.42  ? 982  ALA A N     1 
ATOM   5750  C  CA    . ALA A 1 964  ? 155.729 143.660 88.636  1.00 64.42  ? 982  ALA A CA    1 
ATOM   5751  C  C     . ALA A 1 964  ? 156.227 143.535 87.202  1.00 64.42  ? 982  ALA A C     1 
ATOM   5752  O  O     . ALA A 1 964  ? 156.076 142.479 86.578  1.00 64.42  ? 982  ALA A O     1 
ATOM   5753  C  CB    . ALA A 1 964  ? 154.346 144.306 88.669  1.00 64.42  ? 982  ALA A CB    1 
ATOM   5754  N  N     . GLN A 1 965  ? 156.818 144.603 86.659  1.00 65.41  ? 983  GLN A N     1 
ATOM   5755  C  CA    . GLN A 1 965  ? 157.370 144.531 85.311  1.00 65.41  ? 983  GLN A CA    1 
ATOM   5756  C  C     . GLN A 1 965  ? 158.484 143.496 85.232  1.00 65.41  ? 983  GLN A C     1 
ATOM   5757  O  O     . GLN A 1 965  ? 158.533 142.698 84.288  1.00 65.41  ? 983  GLN A O     1 
ATOM   5758  C  CB    . GLN A 1 965  ? 157.875 145.909 84.879  1.00 65.41  ? 983  GLN A CB    1 
ATOM   5759  C  CG    . GLN A 1 965  ? 158.526 145.947 83.504  1.00 65.41  ? 983  GLN A CG    1 
ATOM   5760  C  CD    . GLN A 1 965  ? 160.027 145.732 83.559  1.00 65.41  ? 983  GLN A CD    1 
ATOM   5761  O  OE1   . GLN A 1 965  ? 160.621 145.689 84.636  1.00 65.41  ? 983  GLN A OE1   1 
ATOM   5762  N  NE2   . GLN A 1 965  ? 160.648 145.595 82.393  1.00 65.41  ? 983  GLN A NE2   1 
ATOM   5763  N  N     . GLN A 1 966  ? 159.383 143.486 86.219  1.00 65.70  ? 984  GLN A N     1 
ATOM   5764  C  CA    . GLN A 1 966  ? 160.449 142.488 86.224  1.00 65.70  ? 984  GLN A CA    1 
ATOM   5765  C  C     . GLN A 1 966  ? 159.907 141.084 86.457  1.00 65.70  ? 984  GLN A C     1 
ATOM   5766  O  O     . GLN A 1 966  ? 160.448 140.113 85.916  1.00 65.70  ? 984  GLN A O     1 
ATOM   5767  C  CB    . GLN A 1 966  ? 161.492 142.837 87.285  1.00 65.70  ? 984  GLN A CB    1 
ATOM   5768  C  CG    . GLN A 1 966  ? 162.262 144.114 86.999  1.00 65.70  ? 984  GLN A CG    1 
ATOM   5769  C  CD    . GLN A 1 966  ? 163.101 144.021 85.739  1.00 65.70  ? 984  GLN A CD    1 
ATOM   5770  O  OE1   . GLN A 1 966  ? 163.485 142.932 85.313  1.00 65.70  ? 984  GLN A OE1   1 
ATOM   5771  N  NE2   . GLN A 1 966  ? 163.387 145.168 85.135  1.00 65.70  ? 984  GLN A NE2   1 
ATOM   5772  N  N     . MET A 1 967  ? 158.848 140.957 87.254  1.00 63.69  ? 985  MET A N     1 
ATOM   5773  C  CA    . MET A 1 967  ? 158.285 139.655 87.582  1.00 63.69  ? 985  MET A CA    1 
ATOM   5774  C  C     . MET A 1 967  ? 157.473 139.078 86.430  1.00 63.69  ? 985  MET A C     1 
ATOM   5775  O  O     . MET A 1 967  ? 157.287 137.859 86.357  1.00 63.69  ? 985  MET A O     1 
ATOM   5776  C  CB    . MET A 1 967  ? 157.422 139.791 88.836  1.00 63.69  ? 985  MET A CB    1 
ATOM   5777  C  CG    . MET A 1 967  ? 157.128 138.507 89.570  1.00 63.69  ? 985  MET A CG    1 
ATOM   5778  S  SD    . MET A 1 967  ? 156.513 138.871 91.227  1.00 63.69  ? 985  MET A SD    1 
ATOM   5779  C  CE    . MET A 1 967  ? 155.491 140.309 90.914  1.00 63.69  ? 985  MET A CE    1 
ATOM   5780  N  N     . TYR A 1 968  ? 156.982 139.933 85.535  1.00 56.83  ? 986  TYR A N     1 
ATOM   5781  C  CA    . TYR A 1 968  ? 156.266 139.474 84.352  1.00 56.83  ? 986  TYR A CA    1 
ATOM   5782  C  C     . TYR A 1 968  ? 157.176 139.294 83.146  1.00 56.83  ? 986  TYR A C     1 
ATOM   5783  O  O     . TYR A 1 968  ? 156.927 138.408 82.321  1.00 56.83  ? 986  TYR A O     1 
ATOM   5784  C  CB    . TYR A 1 968  ? 155.143 140.455 84.001  1.00 56.83  ? 986  TYR A CB    1 
ATOM   5785  C  CG    . TYR A 1 968  ? 153.804 140.101 84.609  1.00 56.83  ? 986  TYR A CG    1 
ATOM   5786  C  CD1   . TYR A 1 968  ? 153.570 140.267 85.964  1.00 56.83  ? 986  TYR A CD1   1 
ATOM   5787  C  CD2   . TYR A 1 968  ? 152.773 139.610 83.822  1.00 56.83  ? 986  TYR A CD2   1 
ATOM   5788  C  CE1   . TYR A 1 968  ? 152.348 139.946 86.520  1.00 56.83  ? 986  TYR A CE1   1 
ATOM   5789  C  CE2   . TYR A 1 968  ? 151.548 139.287 84.369  1.00 56.83  ? 986  TYR A CE2   1 
ATOM   5790  C  CZ    . TYR A 1 968  ? 151.342 139.458 85.718  1.00 56.83  ? 986  TYR A CZ    1 
ATOM   5791  O  OH    . TYR A 1 968  ? 150.123 139.138 86.268  1.00 56.83  ? 986  TYR A OH    1 
ATOM   5792  N  N     . ALA A 1 969  ? 158.226 140.109 83.024  1.00 54.64  ? 987  ALA A N     1 
ATOM   5793  C  CA    . ALA A 1 969  ? 159.126 139.990 81.881  1.00 54.64  ? 987  ALA A CA    1 
ATOM   5794  C  C     . ALA A 1 969  ? 159.873 138.663 81.898  1.00 54.64  ? 987  ALA A C     1 
ATOM   5795  O  O     . ALA A 1 969  ? 160.177 138.102 80.840  1.00 54.64  ? 987  ALA A O     1 
ATOM   5796  C  CB    . ALA A 1 969  ? 160.110 141.159 81.863  1.00 54.64  ? 987  ALA A CB    1 
ATOM   5797  N  N     . ALA A 1 970  ? 160.178 138.146 83.090  1.00 50.92  ? 988  ALA A N     1 
ATOM   5798  C  CA    . ALA A 1 970  ? 160.903 136.887 83.188  1.00 50.92  ? 988  ALA A CA    1 
ATOM   5799  C  C     . ALA A 1 970  ? 160.031 135.686 82.851  1.00 50.92  ? 988  ALA A C     1 
ATOM   5800  O  O     . ALA A 1 970  ? 160.558 134.665 82.397  1.00 50.92  ? 988  ALA A O     1 
ATOM   5801  C  CB    . ALA A 1 970  ? 161.490 136.725 84.590  1.00 50.92  ? 988  ALA A CB    1 
ATOM   5802  N  N     . THR A 1 971  ? 158.719 135.778 83.057  1.00 53.65  ? 989  THR A N     1 
ATOM   5803  C  CA    . THR A 1 971  ? 157.811 134.670 82.787  1.00 53.65  ? 989  THR A CA    1 
ATOM   5804  C  C     . THR A 1 971  ? 156.958 134.893 81.548  1.00 53.65  ? 989  THR A C     1 
ATOM   5805  O  O     . THR A 1 971  ? 156.949 134.050 80.647  1.00 53.65  ? 989  THR A O     1 
ATOM   5806  C  CB    . THR A 1 971  ? 156.902 134.419 83.997  1.00 53.65  ? 989  THR A CB    1 
ATOM   5807  O  OG1   . THR A 1 971  ? 156.096 135.578 84.242  1.00 53.65  ? 989  THR A OG1   1 
ATOM   5808  C  CG2   . THR A 1 971  ? 157.733 134.116 85.232  1.00 53.65  ? 989  THR A CG2   1 
ATOM   5809  N  N     . LYS A 1 972  ? 156.230 136.009 81.478  1.00 53.32  ? 990  LYS A N     1 
ATOM   5810  C  CA    . LYS A 1 972  ? 155.419 136.279 80.296  1.00 53.32  ? 990  LYS A CA    1 
ATOM   5811  C  C     . LYS A 1 972  ? 156.297 136.576 79.088  1.00 53.32  ? 990  LYS A C     1 
ATOM   5812  O  O     . LYS A 1 972  ? 156.108 135.997 78.014  1.00 53.32  ? 990  LYS A O     1 
ATOM   5813  C  CB    . LYS A 1 972  ? 154.459 137.438 80.567  1.00 53.32  ? 990  LYS A CB    1 
ATOM   5814  N  N     . GLY A 1 973  ? 157.273 137.460 79.250  1.00 53.94  ? 991  GLY A N     1 
ATOM   5815  C  CA    . GLY A 1 973  ? 158.180 137.804 78.174  1.00 53.94  ? 991  GLY A CA    1 
ATOM   5816  C  C     . GLY A 1 973  ? 157.868 139.153 77.557  1.00 53.94  ? 991  GLY A C     1 
ATOM   5817  O  O     . GLY A 1 973  ? 157.063 139.944 78.058  1.00 53.94  ? 991  GLY A O     1 
ATOM   5818  N  N     . LEU A 1 974  ? 158.538 139.413 76.438  1.00 59.29  ? 992  LEU A N     1 
ATOM   5819  C  CA    . LEU A 1 974  ? 158.360 140.636 75.669  1.00 59.29  ? 992  LEU A CA    1 
ATOM   5820  C  C     . LEU A 1 974  ? 157.799 140.281 74.300  1.00 59.29  ? 992  LEU A C     1 
ATOM   5821  O  O     . LEU A 1 974  ? 158.313 139.378 73.632  1.00 59.29  ? 992  LEU A O     1 
ATOM   5822  C  CB    . LEU A 1 974  ? 159.680 141.399 75.514  1.00 59.29  ? 992  LEU A CB    1 
ATOM   5823  C  CG    . LEU A 1 974  ? 160.451 141.791 76.778  1.00 59.29  ? 992  LEU A CG    1 
ATOM   5824  C  CD1   . LEU A 1 974  ? 161.405 140.685 77.212  1.00 59.29  ? 992  LEU A CD1   1 
ATOM   5825  C  CD2   . LEU A 1 974  ? 161.203 143.094 76.562  1.00 59.29  ? 992  LEU A CD2   1 
ATOM   5826  N  N     . ARG A 1 975  ? 156.753 140.988 73.886  1.00 58.72  ? 993  ARG A N     1 
ATOM   5827  C  CA    . ARG A 1 975  ? 156.119 140.724 72.599  1.00 58.72  ? 993  ARG A CA    1 
ATOM   5828  C  C     . ARG A 1 975  ? 156.303 141.895 71.641  1.00 58.72  ? 993  ARG A C     1 
ATOM   5829  O  O     . ARG A 1 975  ? 156.536 143.026 72.067  1.00 58.72  ? 993  ARG A O     1 
ATOM   5830  C  CB    . ARG A 1 975  ? 154.632 140.429 72.785  1.00 58.72  ? 993  ARG A CB    1 
ATOM   5831  C  CG    . ARG A 1 975  ? 153.811 141.625 73.231  1.00 58.72  ? 993  ARG A CG    1 
ATOM   5832  C  CD    . ARG A 1 975  ? 152.423 141.195 73.661  1.00 58.72  ? 993  ARG A CD    1 
ATOM   5833  N  NE    . ARG A 1 975  ? 151.859 140.210 72.747  1.00 58.72  ? 993  ARG A NE    1 
ATOM   5834  C  CZ    . ARG A 1 975  ? 150.679 139.629 72.908  1.00 58.72  ? 993  ARG A CZ    1 
ATOM   5835  N  NH1   . ARG A 1 975  ? 149.900 139.920 73.938  1.00 58.72  ? 993  ARG A NH1   1 
ATOM   5836  N  NH2   . ARG A 1 975  ? 150.269 138.733 72.016  1.00 58.72  ? 993  ARG A NH2   1 
ATOM   5837  N  N     . TRP A 1 1031 ? 154.823 136.771 72.721  1.00 56.55  ? 1049 TRP A N     1 
ATOM   5838  C  CA    . TRP A 1 1031 ? 155.966 137.022 73.590  1.00 56.55  ? 1049 TRP A CA    1 
ATOM   5839  C  C     . TRP A 1 1031 ? 157.133 136.099 73.265  1.00 56.55  ? 1049 TRP A C     1 
ATOM   5840  O  O     . TRP A 1 1031 ? 156.964 135.073 72.607  1.00 56.55  ? 1049 TRP A O     1 
ATOM   5841  C  CB    . TRP A 1 1031 ? 155.577 136.851 75.057  1.00 56.55  ? 1049 TRP A CB    1 
ATOM   5842  C  CG    . TRP A 1 1031 ? 154.679 137.918 75.597  1.00 56.55  ? 1049 TRP A CG    1 
ATOM   5843  C  CD1   . TRP A 1 1031 ? 155.028 139.195 75.925  1.00 56.55  ? 1049 TRP A CD1   1 
ATOM   5844  C  CD2   . TRP A 1 1031 ? 153.286 137.792 75.902  1.00 56.55  ? 1049 TRP A CD2   1 
ATOM   5845  N  NE1   . TRP A 1 1031 ? 153.935 139.877 76.403  1.00 56.55  ? 1049 TRP A NE1   1 
ATOM   5846  C  CE2   . TRP A 1 1031 ? 152.853 139.037 76.399  1.00 56.55  ? 1049 TRP A CE2   1 
ATOM   5847  C  CE3   . TRP A 1 1031 ? 152.361 136.750 75.796  1.00 56.55  ? 1049 TRP A CE3   1 
ATOM   5848  C  CZ2   . TRP A 1 1031 ? 151.538 139.267 76.789  1.00 56.55  ? 1049 TRP A CZ2   1 
ATOM   5849  C  CZ3   . TRP A 1 1031 ? 151.057 136.981 76.183  1.00 56.55  ? 1049 TRP A CZ3   1 
ATOM   5850  C  CH2   . TRP A 1 1031 ? 150.657 138.228 76.675  1.00 56.55  ? 1049 TRP A CH2   1 
ATOM   5851  N  N     . LYS A 1 1032 ? 158.320 136.473 73.737  1.00 61.13  ? 1050 LYS A N     1 
ATOM   5852  C  CA    . LYS A 1 1032 ? 159.514 135.665 73.544  1.00 61.13  ? 1050 LYS A CA    1 
ATOM   5853  C  C     . LYS A 1 1032 ? 160.515 136.015 74.635  1.00 61.13  ? 1050 LYS A C     1 
ATOM   5854  O  O     . LYS A 1 1032 ? 160.694 137.189 74.964  1.00 61.13  ? 1050 LYS A O     1 
ATOM   5855  C  CB    . LYS A 1 1032 ? 160.121 135.895 72.154  1.00 61.13  ? 1050 LYS A CB    1 
ATOM   5856  C  CG    . LYS A 1 1032 ? 161.035 134.778 71.661  1.00 61.13  ? 1050 LYS A CG    1 
ATOM   5857  C  CD    . LYS A 1 1032 ? 162.472 134.962 72.126  1.00 61.13  ? 1050 LYS A CD    1 
ATOM   5858  C  CE    . LYS A 1 1032 ? 163.362 133.845 71.607  1.00 61.13  ? 1050 LYS A CE    1 
ATOM   5859  N  NZ    . LYS A 1 1032 ? 164.769 133.999 72.067  1.00 61.13  ? 1050 LYS A NZ    1 
ATOM   5860  N  N     . GLY A 1 1033 ? 161.165 134.991 75.185  1.00 58.78  ? 1051 GLY A N     1 
ATOM   5861  C  CA    . GLY A 1 1033 ? 162.170 135.177 76.210  1.00 58.78  ? 1051 GLY A CA    1 
ATOM   5862  C  C     . GLY A 1 1033 ? 161.721 134.889 77.625  1.00 58.78  ? 1051 GLY A C     1 
ATOM   5863  O  O     . GLY A 1 1033 ? 162.527 135.037 78.552  1.00 58.78  ? 1051 GLY A O     1 
ATOM   5864  N  N     . GLY A 1 1034 ? 160.469 134.486 77.826  1.00 52.50  ? 1052 GLY A N     1 
ATOM   5865  C  CA    . GLY A 1 1034 ? 159.986 134.167 79.155  1.00 52.50  ? 1052 GLY A CA    1 
ATOM   5866  C  C     . GLY A 1 1034 ? 159.682 132.695 79.327  1.00 52.50  ? 1052 GLY A C     1 
ATOM   5867  O  O     . GLY A 1 1034 ? 159.467 131.982 78.342  1.00 52.50  ? 1052 GLY A O     1 
ATOM   5868  N  N     . THR A 1 1035 ? 159.656 132.226 80.576  1.00 53.36  ? 1053 THR A N     1 
ATOM   5869  C  CA    . THR A 1 1035 ? 159.403 130.815 80.841  1.00 53.36  ? 1053 THR A CA    1 
ATOM   5870  C  C     . THR A 1 1035 ? 157.986 130.400 80.473  1.00 53.36  ? 1053 THR A C     1 
ATOM   5871  O  O     . THR A 1 1035 ? 157.722 129.202 80.326  1.00 53.36  ? 1053 THR A O     1 
ATOM   5872  C  CB    . THR A 1 1035 ? 159.659 130.500 82.314  1.00 53.36  ? 1053 THR A CB    1 
ATOM   5873  O  OG1   . THR A 1 1035 ? 158.575 131.001 83.105  1.00 53.36  ? 1053 THR A OG1   1 
ATOM   5874  C  CG2   . THR A 1 1035 ? 160.949 131.155 82.775  1.00 53.36  ? 1053 THR A CG2   1 
ATOM   5875  N  N     . GLU A 1 1036 ? 157.074 131.356 80.322  1.00 56.05  ? 1054 GLU A N     1 
ATOM   5876  C  CA    . GLU A 1 1036 ? 155.685 131.079 79.981  1.00 56.05  ? 1054 GLU A CA    1 
ATOM   5877  C  C     . GLU A 1 1036 ? 155.283 131.788 78.693  1.00 56.05  ? 1054 GLU A C     1 
ATOM   5878  O  O     . GLU A 1 1036 ? 154.115 132.129 78.501  1.00 56.05  ? 1054 GLU A O     1 
ATOM   5879  C  CB    . GLU A 1 1036 ? 154.763 131.478 81.131  1.00 56.05  ? 1054 GLU A CB    1 
ATOM   5880  C  CG    . GLU A 1 1036 ? 155.034 130.720 82.420  1.00 56.05  ? 1054 GLU A CG    1 
ATOM   5881  C  CD    . GLU A 1 1036 ? 154.258 131.271 83.597  1.00 56.05  ? 1054 GLU A CD    1 
ATOM   5882  O  OE1   . GLU A 1 1036 ? 153.599 132.319 83.438  1.00 56.05  ? 1054 GLU A OE1   1 
ATOM   5883  O  OE2   . GLU A 1 1036 ? 154.310 130.657 84.683  1.00 56.05  ? 1054 GLU A OE2   1 
ATOM   5884  N  N     . SER A 1 1037 ? 156.253 132.026 77.808  1.00 57.56  ? 1055 SER A N     1 
ATOM   5885  C  CA    . SER A 1 1037 ? 155.957 132.695 76.546  1.00 57.56  ? 1055 SER A CA    1 
ATOM   5886  C  C     . SER A 1 1037 ? 155.000 131.869 75.700  1.00 57.56  ? 1055 SER A C     1 
ATOM   5887  O  O     . SER A 1 1037 ? 153.965 132.370 75.249  1.00 57.56  ? 1055 SER A O     1 
ATOM   5888  C  CB    . SER A 1 1037 ? 157.252 132.966 75.781  1.00 57.56  ? 1055 SER A CB    1 
ATOM   5889  O  OG    . SER A 1 1037 ? 158.173 133.683 76.580  1.00 57.56  ? 1055 SER A OG    1 
ATOM   5890  N  N     . GLU A 1 1038 ? 155.321 130.592 75.488  1.00 54.61  ? 1056 GLU A N     1 
ATOM   5891  C  CA    . GLU A 1 1038 ? 154.465 129.750 74.659  1.00 54.61  ? 1056 GLU A CA    1 
ATOM   5892  C  C     . GLU A 1 1038 ? 153.133 129.468 75.336  1.00 54.61  ? 1056 GLU A C     1 
ATOM   5893  O  O     . GLU A 1 1038 ? 152.107 129.364 74.658  1.00 54.61  ? 1056 GLU A O     1 
ATOM   5894  C  CB    . GLU A 1 1038 ? 155.176 128.442 74.315  1.00 54.61  ? 1056 GLU A CB    1 
ATOM   5895  C  CG    . GLU A 1 1038 ? 156.342 128.610 73.358  1.00 54.61  ? 1056 GLU A CG    1 
ATOM   5896  C  CD    . GLU A 1 1038 ? 157.574 129.184 74.028  1.00 54.61  ? 1056 GLU A CD    1 
ATOM   5897  O  OE1   . GLU A 1 1038 ? 157.622 129.198 75.276  1.00 54.61  ? 1056 GLU A OE1   1 
ATOM   5898  O  OE2   . GLU A 1 1038 ? 158.495 129.623 73.306  1.00 54.61  ? 1056 GLU A OE2   1 
ATOM   5899  N  N     . MET A 1 1039 ? 153.129 129.355 76.663  1.00 54.30  ? 1057 MET A N     1 
ATOM   5900  C  CA    . MET A 1 1039 ? 151.882 129.152 77.392  1.00 54.30  ? 1057 MET A CA    1 
ATOM   5901  C  C     . MET A 1 1039 ? 150.916 130.308 77.159  1.00 54.30  ? 1057 MET A C     1 
ATOM   5902  O  O     . MET A 1 1039 ? 149.772 130.107 76.726  1.00 54.30  ? 1057 MET A O     1 
ATOM   5903  C  CB    . MET A 1 1039 ? 152.200 128.997 78.879  1.00 54.30  ? 1057 MET A CB    1 
ATOM   5904  C  CG    . MET A 1 1039 ? 151.013 128.785 79.785  1.00 54.30  ? 1057 MET A CG    1 
ATOM   5905  S  SD    . MET A 1 1039 ? 151.529 128.962 81.502  1.00 54.30  ? 1057 MET A SD    1 
ATOM   5906  C  CE    . MET A 1 1039 ? 151.273 130.711 81.758  1.00 54.30  ? 1057 MET A CE    1 
ATOM   5907  N  N     . PHE A 1 1040 ? 151.378 131.536 77.402  1.00 54.36  ? 1058 PHE A N     1 
ATOM   5908  C  CA    . PHE A 1 1040 ? 150.525 132.703 77.215  1.00 54.36  ? 1058 PHE A CA    1 
ATOM   5909  C  C     . PHE A 1 1040 ? 150.182 132.909 75.747  1.00 54.36  ? 1058 PHE A C     1 
ATOM   5910  O  O     . PHE A 1 1040 ? 149.076 133.354 75.420  1.00 54.36  ? 1058 PHE A O     1 
ATOM   5911  C  CB    . PHE A 1 1040 ? 151.206 133.945 77.785  1.00 54.36  ? 1058 PHE A CB    1 
ATOM   5912  C  CG    . PHE A 1 1040 ? 151.028 134.106 79.264  1.00 54.36  ? 1058 PHE A CG    1 
ATOM   5913  C  CD1   . PHE A 1 1040 ? 149.908 133.599 79.898  1.00 54.36  ? 1058 PHE A CD1   1 
ATOM   5914  C  CD2   . PHE A 1 1040 ? 151.980 134.767 80.019  1.00 54.36  ? 1058 PHE A CD2   1 
ATOM   5915  C  CE1   . PHE A 1 1040 ? 149.740 133.751 81.256  1.00 54.36  ? 1058 PHE A CE1   1 
ATOM   5916  C  CE2   . PHE A 1 1040 ? 151.819 134.919 81.377  1.00 54.36  ? 1058 PHE A CE2   1 
ATOM   5917  C  CZ    . PHE A 1 1040 ? 150.699 134.409 81.998  1.00 54.36  ? 1058 PHE A CZ    1 
ATOM   5918  N  N     . ASN A 1 1041 ? 151.119 132.600 74.848  1.00 51.71  ? 1059 ASN A N     1 
ATOM   5919  C  CA    . ASN A 1 1041 ? 150.835 132.721 73.423  1.00 51.71  ? 1059 ASN A CA    1 
ATOM   5920  C  C     . ASN A 1 1041 ? 149.721 131.775 73.002  1.00 51.71  ? 1059 ASN A C     1 
ATOM   5921  O  O     . ASN A 1 1041 ? 148.827 132.162 72.245  1.00 51.71  ? 1059 ASN A O     1 
ATOM   5922  C  CB    . ASN A 1 1041 ? 152.098 132.460 72.605  1.00 51.71  ? 1059 ASN A CB    1 
ATOM   5923  C  CG    . ASN A 1 1041 ? 153.074 133.610 72.666  1.00 51.71  ? 1059 ASN A CG    1 
ATOM   5924  O  OD1   . ASN A 1 1041 ? 154.287 133.415 72.612  1.00 51.71  ? 1059 ASN A OD1   1 
ATOM   5925  N  ND2   . ASN A 1 1041 ? 152.549 134.822 72.794  1.00 51.71  ? 1059 ASN A ND2   1 
ATOM   5926  N  N     . LYS A 1 1042 ? 149.749 130.532 73.488  1.00 48.30  ? 1060 LYS A N     1 
ATOM   5927  C  CA    . LYS A 1 1042 ? 148.667 129.608 73.172  1.00 48.30  ? 1060 LYS A CA    1 
ATOM   5928  C  C     . LYS A 1 1042 ? 147.352 130.075 73.777  1.00 48.30  ? 1060 LYS A C     1 
ATOM   5929  O  O     . LYS A 1 1042 ? 146.300 129.978 73.133  1.00 48.30  ? 1060 LYS A O     1 
ATOM   5930  C  CB    . LYS A 1 1042 ? 149.002 128.199 73.653  1.00 48.30  ? 1060 LYS A CB    1 
ATOM   5931  C  CG    . LYS A 1 1042 ? 147.857 127.223 73.444  1.00 48.30  ? 1060 LYS A CG    1 
ATOM   5932  C  CD    . LYS A 1 1042 ? 148.309 125.783 73.530  1.00 48.30  ? 1060 LYS A CD    1 
ATOM   5933  C  CE    . LYS A 1 1042 ? 147.164 124.847 73.193  1.00 48.30  ? 1060 LYS A CE    1 
ATOM   5934  N  NZ    . LYS A 1 1042 ? 146.570 125.176 71.868  1.00 48.30  ? 1060 LYS A NZ    1 
ATOM   5935  N  N     . LEU A 1 1043 ? 147.388 130.586 75.010  1.00 48.65  ? 1061 LEU A N     1 
ATOM   5936  C  CA    . LEU A 1 1043 ? 146.159 131.067 75.634  1.00 48.65  ? 1061 LEU A CA    1 
ATOM   5937  C  C     . LEU A 1 1043 ? 145.543 132.202 74.823  1.00 48.65  ? 1061 LEU A C     1 
ATOM   5938  O  O     . LEU A 1 1043 ? 144.337 132.207 74.551  1.00 48.65  ? 1061 LEU A O     1 
ATOM   5939  C  CB    . LEU A 1 1043 ? 146.434 131.521 77.067  1.00 48.65  ? 1061 LEU A CB    1 
ATOM   5940  C  CG    . LEU A 1 1043 ? 147.000 130.487 78.041  1.00 48.65  ? 1061 LEU A CG    1 
ATOM   5941  C  CD1   . LEU A 1 1043 ? 147.209 131.106 79.414  1.00 48.65  ? 1061 LEU A CD1   1 
ATOM   5942  C  CD2   . LEU A 1 1043 ? 146.110 129.261 78.124  1.00 48.65  ? 1061 LEU A CD2   1 
ATOM   5943  N  N     . GLU A 1 1044 ? 146.367 133.163 74.403  1.00 53.54  ? 1062 GLU A N     1 
ATOM   5944  C  CA    . GLU A 1 1044 ? 145.860 134.280 73.612  1.00 53.54  ? 1062 GLU A CA    1 
ATOM   5945  C  C     . GLU A 1 1044 ? 145.399 133.827 72.232  1.00 53.54  ? 1062 GLU A C     1 
ATOM   5946  O  O     . GLU A 1 1044 ? 144.391 134.323 71.719  1.00 53.54  ? 1062 GLU A O     1 
ATOM   5947  C  CB    . GLU A 1 1044 ? 146.927 135.365 73.490  1.00 53.54  ? 1062 GLU A CB    1 
ATOM   5948  C  CG    . GLU A 1 1044 ? 147.168 136.129 74.773  1.00 53.54  ? 1062 GLU A CG    1 
ATOM   5949  C  CD    . GLU A 1 1044 ? 148.102 137.300 74.578  1.00 53.54  ? 1062 GLU A CD    1 
ATOM   5950  O  OE1   . GLU A 1 1044 ? 149.031 137.186 73.752  1.00 53.54  ? 1062 GLU A OE1   1 
ATOM   5951  O  OE2   . GLU A 1 1044 ? 147.902 138.337 75.244  1.00 53.54  ? 1062 GLU A OE2   1 
ATOM   5952  N  N     . SER A 1 1045 ? 146.124 132.895 71.610  1.00 50.56  ? 1063 SER A N     1 
ATOM   5953  C  CA    . SER A 1 1045 ? 145.744 132.427 70.282  1.00 50.56  ? 1063 SER A CA    1 
ATOM   5954  C  C     . SER A 1 1045 ? 144.421 131.675 70.317  1.00 50.56  ? 1063 SER A C     1 
ATOM   5955  O  O     . SER A 1 1045 ? 143.628 131.761 69.373  1.00 50.56  ? 1063 SER A O     1 
ATOM   5956  C  CB    . SER A 1 1045 ? 146.849 131.544 69.704  1.00 50.56  ? 1063 SER A CB    1 
ATOM   5957  O  OG    . SER A 1 1045 ? 148.094 132.218 69.712  1.00 50.56  ? 1063 SER A OG    1 
ATOM   5958  N  N     . ILE A 1 1046 ? 144.164 130.931 71.396  1.00 42.53  ? 1064 ILE A N     1 
ATOM   5959  C  CA    . ILE A 1 1046 ? 142.913 130.189 71.506  1.00 42.53  ? 1064 ILE A CA    1 
ATOM   5960  C  C     . ILE A 1 1046 ? 141.795 131.026 72.110  1.00 42.53  ? 1064 ILE A C     1 
ATOM   5961  O  O     . ILE A 1 1046 ? 140.626 130.615 72.053  1.00 42.53  ? 1064 ILE A O     1 
ATOM   5962  C  CB    . ILE A 1 1046 ? 143.124 128.896 72.319  1.00 42.53  ? 1064 ILE A CB    1 
ATOM   5963  C  CG1   . ILE A 1 1046 ? 142.143 127.816 71.866  1.00 42.53  ? 1064 ILE A CG1   1 
ATOM   5964  C  CG2   . ILE A 1 1046 ? 142.969 129.164 73.801  1.00 42.53  ? 1064 ILE A CG2   1 
ATOM   5965  C  CD1   . ILE A 1 1046 ? 142.535 126.425 72.297  1.00 42.53  ? 1064 ILE A CD1   1 
ATOM   5966  N  N     . ALA A 1 1047 ? 142.110 132.187 72.682  1.00 48.82  ? 1065 ALA A N     1 
ATOM   5967  C  CA    . ALA A 1 1047 ? 141.081 133.124 73.111  1.00 48.82  ? 1065 ALA A CA    1 
ATOM   5968  C  C     . ALA A 1 1047 ? 140.694 134.120 72.028  1.00 48.82  ? 1065 ALA A C     1 
ATOM   5969  O  O     . ALA A 1 1047 ? 139.579 134.652 72.066  1.00 48.82  ? 1065 ALA A O     1 
ATOM   5970  C  CB    . ALA A 1 1047 ? 141.546 133.889 74.354  1.00 48.82  ? 1065 ALA A CB    1 
ATOM   5971  N  N     . THR A 1 1048 ? 141.589 134.369 71.074  1.00 52.29  ? 1066 THR A N     1 
ATOM   5972  C  CA    . THR A 1 1048 ? 141.327 135.344 70.017  1.00 52.29  ? 1066 THR A CA    1 
ATOM   5973  C  C     . THR A 1 1048 ? 140.759 134.711 68.744  1.00 52.29  ? 1066 THR A C     1 
ATOM   5974  O  O     . THR A 1 1048 ? 140.526 135.402 67.757  1.00 52.29  ? 1066 THR A O     1 
ATOM   5975  C  CB    . THR A 1 1048 ? 142.606 136.128 69.666  1.00 52.29  ? 1066 THR A CB    1 
ATOM   5976  O  OG1   . THR A 1 1048 ? 143.316 136.451 70.866  1.00 52.29  ? 1066 THR A OG1   1 
ATOM   5977  C  CG2   . THR A 1 1048 ? 142.267 137.415 68.934  1.00 52.29  ? 1066 THR A CG2   1 
ATOM   5978  N  N     . SER A 1 1049 ? 140.525 133.405 68.754  1.00 49.69  ? 1067 SER A N     1 
ATOM   5979  C  CA    . SER A 1 1049 ? 139.926 132.769 67.593  1.00 49.69  ? 1067 SER A CA    1 
ATOM   5980  C  C     . SER A 1 1049 ? 138.464 133.186 67.461  1.00 49.69  ? 1067 SER A C     1 
ATOM   5981  O  O     . SER A 1 1049 ? 137.858 133.721 68.392  1.00 49.69  ? 1067 SER A O     1 
ATOM   5982  C  CB    . SER A 1 1049 ? 140.036 131.247 67.690  1.00 49.69  ? 1067 SER A CB    1 
ATOM   5983  O  OG    . SER A 1 1049 ? 139.245 130.742 68.749  1.00 49.69  ? 1067 SER A OG    1 
ATOM   5984  N  N     . ASP A 1 1050 ? 137.897 132.931 66.279  1.00 54.47  ? 1068 ASP A N     1 
ATOM   5985  C  CA    . ASP A 1 1050 ? 136.528 133.362 66.007  1.00 54.47  ? 1068 ASP A CA    1 
ATOM   5986  C  C     . ASP A 1 1050 ? 135.545 132.721 66.978  1.00 54.47  ? 1068 ASP A C     1 
ATOM   5987  O  O     . ASP A 1 1050 ? 134.621 133.382 67.466  1.00 54.47  ? 1068 ASP A O     1 
ATOM   5988  C  CB    . ASP A 1 1050 ? 136.152 133.036 64.563  1.00 54.47  ? 1068 ASP A CB    1 
ATOM   5989  C  CG    . ASP A 1 1050 ? 136.969 133.823 63.558  1.00 54.47  ? 1068 ASP A CG    1 
ATOM   5990  O  OD1   . ASP A 1 1050 ? 138.186 133.566 63.447  1.00 54.47  ? 1068 ASP A OD1   1 
ATOM   5991  O  OD2   . ASP A 1 1050 ? 136.395 134.700 62.880  1.00 54.47  ? 1068 ASP A OD2   1 
ATOM   5992  N  N     . ILE A 1 1051 ? 135.723 131.437 67.264  1.00 46.77  ? 1069 ILE A N     1 
ATOM   5993  C  CA    . ILE A 1 1051 ? 134.971 130.765 68.318  1.00 46.77  ? 1069 ILE A CA    1 
ATOM   5994  C  C     . ILE A 1 1051 ? 135.985 130.150 69.274  1.00 46.77  ? 1069 ILE A C     1 
ATOM   5995  O  O     . ILE A 1 1051 ? 136.477 129.042 69.016  1.00 46.77  ? 1069 ILE A O     1 
ATOM   5996  C  CB    . ILE A 1 1051 ? 134.017 129.702 67.752  1.00 46.77  ? 1069 ILE A CB    1 
ATOM   5997  C  CG1   . ILE A 1 1051 ? 133.123 130.297 66.663  1.00 46.77  ? 1069 ILE A CG1   1 
ATOM   5998  C  CG2   . ILE A 1 1051 ? 133.165 129.111 68.862  1.00 46.77  ? 1069 ILE A CG2   1 
ATOM   5999  C  CD1   . ILE A 1 1051 ? 133.578 129.979 65.254  1.00 46.77  ? 1069 ILE A CD1   1 
ATOM   6000  N  N     . PRO A 1 1052 ? 136.353 130.833 70.357  1.00 41.61  ? 1070 PRO A N     1 
ATOM   6001  C  CA    . PRO A 1 1052 ? 137.337 130.263 71.285  1.00 41.61  ? 1070 PRO A CA    1 
ATOM   6002  C  C     . PRO A 1 1052 ? 136.848 128.950 71.878  1.00 41.61  ? 1070 PRO A C     1 
ATOM   6003  O  O     . PRO A 1 1052 ? 135.673 128.798 72.221  1.00 41.61  ? 1070 PRO A O     1 
ATOM   6004  C  CB    . PRO A 1 1052 ? 137.483 131.349 72.357  1.00 41.61  ? 1070 PRO A CB    1 
ATOM   6005  C  CG    . PRO A 1 1052 ? 137.070 132.610 71.673  1.00 41.61  ? 1070 PRO A CG    1 
ATOM   6006  C  CD    . PRO A 1 1052 ? 135.978 132.208 70.726  1.00 41.61  ? 1070 PRO A CD    1 
ATOM   6007  N  N     . ARG A 1 1053 ? 137.770 127.999 71.999  1.00 36.54  ? 1071 ARG A N     1 
ATOM   6008  C  CA    . ARG A 1 1053 ? 137.467 126.665 72.492  1.00 36.54  ? 1071 ARG A CA    1 
ATOM   6009  C  C     . ARG A 1 1053 ? 138.468 126.278 73.569  1.00 36.54  ? 1071 ARG A C     1 
ATOM   6010  O  O     . ARG A 1 1053 ? 139.610 126.743 73.573  1.00 36.54  ? 1071 ARG A O     1 
ATOM   6011  C  CB    . ARG A 1 1053 ? 137.507 125.616 71.369  1.00 36.54  ? 1071 ARG A CB    1 
ATOM   6012  C  CG    . ARG A 1 1053 ? 136.850 126.051 70.074  1.00 36.54  ? 1071 ARG A CG    1 
ATOM   6013  C  CD    . ARG A 1 1053 ? 135.363 126.249 70.255  1.00 36.54  ? 1071 ARG A CD    1 
ATOM   6014  N  NE    . ARG A 1 1053 ? 134.600 125.075 69.851  1.00 36.54  ? 1071 ARG A NE    1 
ATOM   6015  C  CZ    . ARG A 1 1053 ? 134.038 124.926 68.660  1.00 36.54  ? 1071 ARG A CZ    1 
ATOM   6016  N  NH1   . ARG A 1 1053 ? 134.137 125.859 67.727  1.00 36.54  ? 1071 ARG A NH1   1 
ATOM   6017  N  NH2   . ARG A 1 1053 ? 133.356 123.815 68.399  1.00 36.54  ? 1071 ARG A NH2   1 
ATOM   6018  N  N     . THR A 1 1054 ? 138.025 125.433 74.486  1.00 31.98  ? 1072 THR A N     1 
ATOM   6019  C  CA    . THR A 1 1054 ? 138.956 124.797 75.405  1.00 31.98  ? 1072 THR A CA    1 
ATOM   6020  C  C     . THR A 1 1054 ? 139.765 123.761 74.633  1.00 31.98  ? 1072 THR A C     1 
ATOM   6021  O  O     . THR A 1 1054 ? 139.180 122.900 73.966  1.00 31.98  ? 1072 THR A O     1 
ATOM   6022  C  CB    . THR A 1 1054 ? 138.215 124.139 76.563  1.00 31.98  ? 1072 THR A CB    1 
ATOM   6023  O  OG1   . THR A 1 1054 ? 137.369 123.101 76.059  1.00 31.98  ? 1072 THR A OG1   1 
ATOM   6024  C  CG2   . THR A 1 1054 ? 137.365 125.159 77.294  1.00 31.98  ? 1072 THR A CG2   1 
ATOM   6025  N  N     . PRO A 1 1055 ? 141.097 123.807 74.692  1.00 30.92  ? 1073 PRO A N     1 
ATOM   6026  C  CA    . PRO A 1 1055 ? 141.902 122.927 73.829  1.00 30.92  ? 1073 PRO A CA    1 
ATOM   6027  C  C     . PRO A 1 1055 ? 141.686 121.443 74.074  1.00 30.92  ? 1073 PRO A C     1 
ATOM   6028  O  O     . PRO A 1 1055 ? 142.059 120.634 73.217  1.00 30.92  ? 1073 PRO A O     1 
ATOM   6029  C  CB    . PRO A 1 1055 ? 143.344 123.343 74.153  1.00 30.92  ? 1073 PRO A CB    1 
ATOM   6030  C  CG    . PRO A 1 1055 ? 143.261 124.027 75.472  1.00 30.92  ? 1073 PRO A CG    1 
ATOM   6031  C  CD    . PRO A 1 1055 ? 141.934 124.702 75.506  1.00 30.92  ? 1073 PRO A CD    1 
ATOM   6032  N  N     . VAL A 1 1056 ? 141.099 121.055 75.204  1.00 31.08  ? 1074 VAL A N     1 
ATOM   6033  C  CA    . VAL A 1 1056 ? 140.909 119.642 75.509  1.00 31.08  ? 1074 VAL A CA    1 
ATOM   6034  C  C     . VAL A 1 1056 ? 139.545 119.165 75.026  1.00 31.08  ? 1074 VAL A C     1 
ATOM   6035  O  O     . VAL A 1 1056 ? 139.455 118.270 74.180  1.00 31.08  ? 1074 VAL A O     1 
ATOM   6036  C  CB    . VAL A 1 1056 ? 141.075 119.377 77.015  1.00 31.08  ? 1074 VAL A CB    1 
ATOM   6037  C  CG1   . VAL A 1 1056 ? 140.760 117.925 77.333  1.00 31.08  ? 1074 VAL A CG1   1 
ATOM   6038  C  CG2   . VAL A 1 1056 ? 142.481 119.727 77.449  1.00 31.08  ? 1074 VAL A CG2   1 
ATOM   6039  N  N     . LEU A 1 1057 ? 138.474 119.754 75.557  1.00 28.87  ? 1075 LEU A N     1 
ATOM   6040  C  CA    . LEU A 1 1057 ? 137.126 119.300 75.247  1.00 28.87  ? 1075 LEU A CA    1 
ATOM   6041  C  C     . LEU A 1 1057 ? 136.430 120.136 74.181  1.00 28.87  ? 1075 LEU A C     1 
ATOM   6042  O  O     . LEU A 1 1057 ? 135.383 119.718 73.679  1.00 28.87  ? 1075 LEU A O     1 
ATOM   6043  C  CB    . LEU A 1 1057 ? 136.268 119.280 76.517  1.00 28.87  ? 1075 LEU A CB    1 
ATOM   6044  C  CG    . LEU A 1 1057 ? 136.699 118.283 77.592  1.00 28.87  ? 1075 LEU A CG    1 
ATOM   6045  C  CD1   . LEU A 1 1057 ? 135.663 118.194 78.698  1.00 28.87  ? 1075 LEU A CD1   1 
ATOM   6046  C  CD2   . LEU A 1 1057 ? 136.940 116.920 76.976  1.00 28.87  ? 1075 LEU A CD2   1 
ATOM   6047  N  N     . GLY A 1 1058 ? 136.974 121.297 73.826  1.00 31.49  ? 1076 GLY A N     1 
ATOM   6048  C  CA    . GLY A 1 1058 ? 136.416 122.075 72.738  1.00 31.49  ? 1076 GLY A CA    1 
ATOM   6049  C  C     . GLY A 1 1058 ? 135.179 122.876 73.066  1.00 31.49  ? 1076 GLY A C     1 
ATOM   6050  O  O     . GLY A 1 1058 ? 134.484 123.314 72.145  1.00 31.49  ? 1076 GLY A O     1 
ATOM   6051  N  N     . CYS A 1 1059 ? 134.873 123.079 74.344  1.00 32.82  ? 1077 CYS A N     1 
ATOM   6052  C  CA    . CYS A 1 1059 ? 133.717 123.884 74.711  1.00 32.82  ? 1077 CYS A CA    1 
ATOM   6053  C  C     . CYS A 1 1059 ? 133.932 125.341 74.316  1.00 32.82  ? 1077 CYS A C     1 
ATOM   6054  O  O     . CYS A 1 1059 ? 135.050 125.858 74.348  1.00 32.82  ? 1077 CYS A O     1 
ATOM   6055  C  CB    . CYS A 1 1059 ? 133.449 123.783 76.211  1.00 32.82  ? 1077 CYS A CB    1 
ATOM   6056  S  SG    . CYS A 1 1059 ? 133.107 122.112 76.786  1.00 32.82  ? 1077 CYS A SG    1 
ATOM   6057  N  N     . CYS A 1 1060 ? 132.840 126.007 73.953  1.00 33.79  ? 1078 CYS A N     1 
ATOM   6058  C  CA    . CYS A 1 1060 ? 132.907 127.366 73.438  1.00 33.79  ? 1078 CYS A CA    1 
ATOM   6059  C  C     . CYS A 1 1060 ? 132.764 128.388 74.559  1.00 33.79  ? 1078 CYS A C     1 
ATOM   6060  O  O     . CYS A 1 1060 ? 132.089 128.152 75.564  1.00 33.79  ? 1078 CYS A O     1 
ATOM   6061  C  CB    . CYS A 1 1060 ? 131.819 127.600 72.388  1.00 33.79  ? 1078 CYS A CB    1 
ATOM   6062  S  SG    . CYS A 1 1060 ? 131.892 126.498 70.959  1.00 33.79  ? 1078 CYS A SG    1 
ATOM   6063  N  N     . ILE A 1 1061 ? 133.410 129.537 74.368  1.00 36.37  ? 1079 ILE A N     1 
ATOM   6064  C  CA    . ILE A 1 1061 ? 133.331 130.652 75.306  1.00 36.37  ? 1079 ILE A CA    1 
ATOM   6065  C  C     . ILE A 1 1061 ? 131.940 131.265 75.215  1.00 36.37  ? 1079 ILE A C     1 
ATOM   6066  O  O     . ILE A 1 1061 ? 131.179 130.966 74.288  1.00 36.37  ? 1079 ILE A O     1 
ATOM   6067  C  CB    . ILE A 1 1061 ? 134.429 131.693 75.016  1.00 36.37  ? 1079 ILE A CB    1 
ATOM   6068  C  CG1   . ILE A 1 1061 ? 134.688 132.578 76.236  1.00 36.37  ? 1079 ILE A CG1   1 
ATOM   6069  C  CG2   . ILE A 1 1061 ? 134.050 132.543 73.819  1.00 36.37  ? 1079 ILE A CG2   1 
ATOM   6070  C  CD1   . ILE A 1 1061 ? 135.817 133.563 76.042  1.00 36.37  ? 1079 ILE A CD1   1 
ATOM   6071  N  N     . SER A 1 1062 ? 131.594 132.119 76.175  1.00 39.27  ? 1080 SER A N     1 
ATOM   6072  C  CA    . SER A 1 1062 ? 130.280 132.744 76.198  1.00 39.27  ? 1080 SER A CA    1 
ATOM   6073  C  C     . SER A 1 1062 ? 130.096 133.679 75.007  1.00 39.27  ? 1080 SER A C     1 
ATOM   6074  O  O     . SER A 1 1062 ? 131.049 134.277 74.501  1.00 39.27  ? 1080 SER A O     1 
ATOM   6075  C  CB    . SER A 1 1062 ? 130.084 133.517 77.500  1.00 39.27  ? 1080 SER A CB    1 
ATOM   6076  O  OG    . SER A 1 1062 ? 128.863 134.231 77.490  1.00 39.27  ? 1080 SER A OG    1 
ATOM   6077  N  N     . ARG A 1 1063 ? 128.842 133.803 74.561  1.00 42.63  ? 1081 ARG A N     1 
ATOM   6078  C  CA    . ARG A 1 1063 ? 128.535 134.677 73.434  1.00 42.63  ? 1081 ARG A CA    1 
ATOM   6079  C  C     . ARG A 1 1063 ? 128.837 136.137 73.734  1.00 42.63  ? 1081 ARG A C     1 
ATOM   6080  O  O     . ARG A 1 1063 ? 129.008 136.927 72.800  1.00 42.63  ? 1081 ARG A O     1 
ATOM   6081  C  CB    . ARG A 1 1063 ? 127.068 134.529 73.032  1.00 42.63  ? 1081 ARG A CB    1 
ATOM   6082  C  CG    . ARG A 1 1063 ? 126.712 133.168 72.480  1.00 42.63  ? 1081 ARG A CG    1 
ATOM   6083  C  CD    . ARG A 1 1063 ? 125.304 133.161 71.924  1.00 42.63  ? 1081 ARG A CD    1 
ATOM   6084  N  NE    . ARG A 1 1063 ? 124.314 133.475 72.945  1.00 42.63  ? 1081 ARG A NE    1 
ATOM   6085  C  CZ    . ARG A 1 1063 ? 123.007 133.527 72.730  1.00 42.63  ? 1081 ARG A CZ    1 
ATOM   6086  N  NH1   . ARG A 1 1063 ? 122.494 133.293 71.534  1.00 42.63  ? 1081 ARG A NH1   1 
ATOM   6087  N  NH2   . ARG A 1 1063 ? 122.194 133.819 73.741  1.00 42.63  ? 1081 ARG A NH2   1 
ATOM   6088  N  N     . ALA A 1 1064 ? 128.908 136.513 75.009  1.00 47.31  ? 1082 ALA A N     1 
ATOM   6089  C  CA    . ALA A 1 1064 ? 129.248 137.878 75.386  1.00 47.31  ? 1082 ALA A CA    1 
ATOM   6090  C  C     . ALA A 1 1064 ? 130.748 138.140 75.381  1.00 47.31  ? 1082 ALA A C     1 
ATOM   6091  O  O     . ALA A 1 1064 ? 131.159 139.285 75.599  1.00 47.31  ? 1082 ALA A O     1 
ATOM   6092  C  CB    . ALA A 1 1064 ? 128.676 138.198 76.768  1.00 47.31  ? 1082 ALA A CB    1 
ATOM   6093  N  N     . LEU A 1 1065 ? 131.571 137.119 75.146  1.00 47.97  ? 1083 LEU A N     1 
ATOM   6094  C  CA    . LEU A 1 1065 ? 133.017 137.273 75.159  1.00 47.97  ? 1083 LEU A CA    1 
ATOM   6095  C  C     . LEU A 1 1065 ? 133.684 136.859 73.855  1.00 47.97  ? 1083 LEU A C     1 
ATOM   6096  O  O     . LEU A 1 1065 ? 134.918 136.861 73.782  1.00 47.97  ? 1083 LEU A O     1 
ATOM   6097  C  CB    . LEU A 1 1065 ? 133.623 136.473 76.320  1.00 47.97  ? 1083 LEU A CB    1 
ATOM   6098  C  CG    . LEU A 1 1065 ? 133.300 136.984 77.725  1.00 47.97  ? 1083 LEU A CG    1 
ATOM   6099  C  CD1   . LEU A 1 1065 ? 133.249 135.834 78.713  1.00 47.97  ? 1083 LEU A CD1   1 
ATOM   6100  C  CD2   . LEU A 1 1065 ? 134.322 138.021 78.161  1.00 47.97  ? 1083 LEU A CD2   1 
ATOM   6101  N  N     . GLU A 1 1066 ? 132.914 136.507 72.829  1.00 53.52  ? 1084 GLU A N     1 
ATOM   6102  C  CA    . GLU A 1 1066 ? 133.500 136.160 71.546  1.00 53.52  ? 1084 GLU A CA    1 
ATOM   6103  C  C     . GLU A 1 1066 ? 134.056 137.407 70.861  1.00 53.52  ? 1084 GLU A C     1 
ATOM   6104  O  O     . GLU A 1 1066 ? 133.570 138.518 71.087  1.00 53.52  ? 1084 GLU A O     1 
ATOM   6105  C  CB    . GLU A 1 1066 ? 132.463 135.492 70.650  1.00 53.52  ? 1084 GLU A CB    1 
ATOM   6106  C  CG    . GLU A 1 1066 ? 131.986 134.147 71.161  1.00 53.52  ? 1084 GLU A CG    1 
ATOM   6107  C  CD    . GLU A 1 1066 ? 130.916 133.540 70.280  1.00 53.52  ? 1084 GLU A CD    1 
ATOM   6108  O  OE1   . GLU A 1 1066 ? 130.328 134.281 69.464  1.00 53.52  ? 1084 GLU A OE1   1 
ATOM   6109  O  OE2   . GLU A 1 1066 ? 130.665 132.323 70.400  1.00 53.52  ? 1084 GLU A OE2   1 
ATOM   6110  N  N     . PRO A 1 1067 ? 135.080 137.250 70.017  1.00 61.40  ? 1085 PRO A N     1 
ATOM   6111  C  CA    . PRO A 1 1067 ? 135.661 138.422 69.342  1.00 61.40  ? 1085 PRO A CA    1 
ATOM   6112  C  C     . PRO A 1 1067 ? 134.706 139.130 68.397  1.00 61.40  ? 1085 PRO A C     1 
ATOM   6113  O  O     . PRO A 1 1067 ? 134.983 140.270 68.007  1.00 61.40  ? 1085 PRO A O     1 
ATOM   6114  C  CB    . PRO A 1 1067 ? 136.858 137.831 68.586  1.00 61.40  ? 1085 PRO A CB    1 
ATOM   6115  C  CG    . PRO A 1 1067 ? 137.204 136.602 69.345  1.00 61.40  ? 1085 PRO A CG    1 
ATOM   6116  C  CD    . PRO A 1 1067 ? 135.891 136.040 69.805  1.00 61.40  ? 1085 PRO A CD    1 
ATOM   6117  N  N     . SER A 1 1068 ? 133.605 138.494 67.996  1.00 65.68  ? 1086 SER A N     1 
ATOM   6118  C  CA    . SER A 1 1068 ? 132.643 139.172 67.136  1.00 65.68  ? 1086 SER A CA    1 
ATOM   6119  C  C     . SER A 1 1068 ? 131.707 140.063 67.945  1.00 65.68  ? 1086 SER A C     1 
ATOM   6120  O  O     . SER A 1 1068 ? 131.487 141.227 67.593  1.00 65.68  ? 1086 SER A O     1 
ATOM   6121  C  CB    . SER A 1 1068 ? 131.844 138.147 66.328  1.00 65.68  ? 1086 SER A CB    1 
ATOM   6122  O  OG    . SER A 1 1068 ? 131.072 137.318 67.178  1.00 65.68  ? 1086 SER A OG    1 
ATOM   6123  N  N     . ALA A 1 1069 ? 131.148 139.532 69.035  1.00 68.16  ? 1087 ALA A N     1 
ATOM   6124  C  CA    . ALA A 1 1069 ? 130.173 140.290 69.815  1.00 68.16  ? 1087 ALA A CA    1 
ATOM   6125  C  C     . ALA A 1 1069 ? 130.839 141.392 70.633  1.00 68.16  ? 1087 ALA A C     1 
ATOM   6126  O  O     . ALA A 1 1069 ? 130.347 142.525 70.679  1.00 68.16  ? 1087 ALA A O     1 
ATOM   6127  C  CB    . ALA A 1 1069 ? 129.384 139.348 70.723  1.00 68.16  ? 1087 ALA A CB    1 
ATOM   6128  N  N     . VAL A 1 1070 ? 131.957 141.081 71.288  1.00 69.90  ? 1088 VAL A N     1 
ATOM   6129  C  CA    . VAL A 1 1070 ? 132.603 142.009 72.211  1.00 69.90  ? 1088 VAL A CA    1 
ATOM   6130  C  C     . VAL A 1 1070 ? 133.885 142.599 71.643  1.00 69.90  ? 1088 VAL A C     1 
ATOM   6131  O  O     . VAL A 1 1070 ? 134.565 143.369 72.340  1.00 69.90  ? 1088 VAL A O     1 
ATOM   6132  C  CB    . VAL A 1 1070 ? 132.866 141.338 73.575  1.00 69.90  ? 1088 VAL A CB    1 
ATOM   6133  C  CG1   . VAL A 1 1070 ? 134.125 140.492 73.534  1.00 69.90  ? 1088 VAL A CG1   1 
ATOM   6134  C  CG2   . VAL A 1 1070 ? 132.924 142.371 74.698  1.00 69.90  ? 1088 VAL A CG2   1 
ATOM   6135  N  N     . GLN A 1 1071 ? 134.229 142.279 70.397  1.00 73.28  ? 1089 GLN A N     1 
ATOM   6136  C  CA    . GLN A 1 1071 ? 135.377 142.863 69.684  1.00 73.28  ? 1089 GLN A CA    1 
ATOM   6137  C  C     . GLN A 1 1071 ? 136.652 142.477 70.432  1.00 73.28  ? 1089 GLN A C     1 
ATOM   6138  O  O     . GLN A 1 1071 ? 136.865 141.282 70.688  1.00 73.28  ? 1089 GLN A O     1 
ATOM   6139  C  CB    . GLN A 1 1071 ? 135.145 144.358 69.499  1.00 73.28  ? 1089 GLN A CB    1 
ATOM   6140  C  CG    . GLN A 1 1071 ? 133.885 144.694 68.724  1.00 73.28  ? 1089 GLN A CG    1 
ATOM   6141  C  CD    . GLN A 1 1071 ? 133.891 144.109 67.328  1.00 73.28  ? 1089 GLN A CD    1 
ATOM   6142  O  OE1   . GLN A 1 1071 ? 134.921 144.095 66.652  1.00 73.28  ? 1089 GLN A OE1   1 
ATOM   6143  N  NE2   . GLN A 1 1071 ? 132.740 143.614 66.889  1.00 73.28  ? 1089 GLN A NE2   1 
ATOM   6144  N  N     . GLU A 1 1072 ? 137.514 143.427 70.796  1.00 74.06  ? 1090 GLU A N     1 
ATOM   6145  C  CA    . GLU A 1 1072 ? 138.779 143.142 71.462  1.00 74.06  ? 1090 GLU A CA    1 
ATOM   6146  C  C     . GLU A 1 1072 ? 138.741 143.518 72.939  1.00 74.06  ? 1090 GLU A C     1 
ATOM   6147  O  O     . GLU A 1 1072 ? 139.737 143.987 73.494  1.00 74.06  ? 1090 GLU A O     1 
ATOM   6148  C  CB    . GLU A 1 1072 ? 139.927 143.866 70.762  1.00 74.06  ? 1090 GLU A CB    1 
ATOM   6149  C  CG    . GLU A 1 1072 ? 140.154 143.436 69.323  1.00 74.06  ? 1090 GLU A CG    1 
ATOM   6150  C  CD    . GLU A 1 1072 ? 141.347 144.128 68.693  1.00 74.06  ? 1090 GLU A CD    1 
ATOM   6151  O  OE1   . GLU A 1 1072 ? 141.994 144.946 69.381  1.00 74.06  ? 1090 GLU A OE1   1 
ATOM   6152  O  OE2   . GLU A 1 1072 ? 141.639 143.854 67.510  1.00 74.06  ? 1090 GLU A OE2   1 
ATOM   6153  N  N     . GLU A 1 1073 ? 137.599 143.318 73.585  1.00 71.15  ? 1091 GLU A N     1 
ATOM   6154  C  CA    . GLU A 1 1073 ? 137.409 143.696 74.976  1.00 71.15  ? 1091 GLU A CA    1 
ATOM   6155  C  C     . GLU A 1 1073 ? 137.483 142.468 75.875  1.00 71.15  ? 1091 GLU A C     1 
ATOM   6156  O  O     . GLU A 1 1073 ? 137.154 141.353 75.462  1.00 71.15  ? 1091 GLU A O     1 
ATOM   6157  C  CB    . GLU A 1 1073 ? 136.066 144.405 75.165  1.00 71.15  ? 1091 GLU A CB    1 
ATOM   6158  C  CG    . GLU A 1 1073 ? 135.991 145.297 76.394  1.00 71.15  ? 1091 GLU A CG    1 
ATOM   6159  C  CD    . GLU A 1 1073 ? 136.799 146.572 76.244  1.00 71.15  ? 1091 GLU A CD    1 
ATOM   6160  O  OE1   . GLU A 1 1073 ? 137.185 146.907 75.104  1.00 71.15  ? 1091 GLU A OE1   1 
ATOM   6161  O  OE2   . GLU A 1 1073 ? 137.047 147.240 77.269  1.00 71.15  ? 1091 GLU A OE2   1 
ATOM   6162  N  N     . PHE A 1 1074 ? 137.933 142.691 77.113  1.00 67.21  ? 1092 PHE A N     1 
ATOM   6163  C  CA    . PHE A 1 1074 ? 138.019 141.649 78.141  1.00 67.21  ? 1092 PHE A CA    1 
ATOM   6164  C  C     . PHE A 1 1074 ? 139.010 140.551 77.747  1.00 67.21  ? 1092 PHE A C     1 
ATOM   6165  O  O     . PHE A 1 1074 ? 138.688 139.362 77.764  1.00 67.21  ? 1092 PHE A O     1 
ATOM   6166  C  CB    . PHE A 1 1074 ? 136.640 141.056 78.449  1.00 67.21  ? 1092 PHE A CB    1 
ATOM   6167  C  CG    . PHE A 1 1074 ? 135.596 142.083 78.782  1.00 67.21  ? 1092 PHE A CG    1 
ATOM   6168  C  CD1   . PHE A 1 1074 ? 135.593 142.716 80.013  1.00 67.21  ? 1092 PHE A CD1   1 
ATOM   6169  C  CD2   . PHE A 1 1074 ? 134.608 142.404 77.867  1.00 67.21  ? 1092 PHE A CD2   1 
ATOM   6170  C  CE1   . PHE A 1 1074 ? 134.628 143.657 80.321  1.00 67.21  ? 1092 PHE A CE1   1 
ATOM   6171  C  CE2   . PHE A 1 1074 ? 133.642 143.344 78.170  1.00 67.21  ? 1092 PHE A CE2   1 
ATOM   6172  C  CZ    . PHE A 1 1074 ? 133.652 143.971 79.397  1.00 67.21  ? 1092 PHE A CZ    1 
ATOM   6173  N  N     . MET A 1 1075 ? 140.229 140.961 77.388  1.00 61.43  ? 1093 MET A N     1 
ATOM   6174  C  CA    . MET A 1 1075 ? 141.281 139.987 77.109  1.00 61.43  ? 1093 MET A CA    1 
ATOM   6175  C  C     . MET A 1 1075 ? 141.629 139.181 78.353  1.00 61.43  ? 1093 MET A C     1 
ATOM   6176  O  O     . MET A 1 1075 ? 141.822 137.960 78.277  1.00 61.43  ? 1093 MET A O     1 
ATOM   6177  C  CB    . MET A 1 1075 ? 142.521 140.691 76.562  1.00 61.43  ? 1093 MET A CB    1 
ATOM   6178  C  CG    . MET A 1 1075 ? 142.429 141.048 75.091  1.00 61.43  ? 1093 MET A CG    1 
ATOM   6179  S  SD    . MET A 1 1075 ? 142.241 139.589 74.050  1.00 61.43  ? 1093 MET A SD    1 
ATOM   6180  C  CE    . MET A 1 1075 ? 142.206 140.334 72.423  1.00 61.43  ? 1093 MET A CE    1 
ATOM   6181  N  N     . THR A 1 1076 ? 141.713 139.848 79.507  1.00 55.46  ? 1094 THR A N     1 
ATOM   6182  C  CA    . THR A 1 1076 ? 141.984 139.146 80.757  1.00 55.46  ? 1094 THR A CA    1 
ATOM   6183  C  C     . THR A 1 1076 ? 140.913 138.104 81.044  1.00 55.46  ? 1094 THR A C     1 
ATOM   6184  O  O     . THR A 1 1076 ? 141.221 136.991 81.486  1.00 55.46  ? 1094 THR A O     1 
ATOM   6185  C  CB    . THR A 1 1076 ? 142.079 140.147 81.908  1.00 55.46  ? 1094 THR A CB    1 
ATOM   6186  O  OG1   . THR A 1 1076 ? 143.207 141.007 81.705  1.00 55.46  ? 1094 THR A OG1   1 
ATOM   6187  C  CG2   . THR A 1 1076 ? 142.228 139.425 83.237  1.00 55.46  ? 1094 THR A CG2   1 
ATOM   6188  N  N     . SER A 1 1077 ? 139.647 138.445 80.793  1.00 52.50  ? 1095 SER A N     1 
ATOM   6189  C  CA    . SER A 1 1077 ? 138.563 137.502 81.040  1.00 52.50  ? 1095 SER A CA    1 
ATOM   6190  C  C     . SER A 1 1077 ? 138.694 136.264 80.162  1.00 52.50  ? 1095 SER A C     1 
ATOM   6191  O  O     . SER A 1 1077 ? 138.519 135.138 80.639  1.00 52.50  ? 1095 SER A O     1 
ATOM   6192  C  CB    . SER A 1 1077 ? 137.216 138.185 80.812  1.00 52.50  ? 1095 SER A CB    1 
ATOM   6193  O  OG    . SER A 1 1077 ? 137.091 139.340 81.624  1.00 52.50  ? 1095 SER A OG    1 
ATOM   6194  N  N     . ARG A 1 1078 ? 139.022 136.447 78.880  1.00 53.38  ? 1096 ARG A N     1 
ATOM   6195  C  CA    . ARG A 1 1078 ? 139.185 135.303 77.986  1.00 53.38  ? 1096 ARG A CA    1 
ATOM   6196  C  C     . ARG A 1 1078 ? 140.378 134.442 78.387  1.00 53.38  ? 1096 ARG A C     1 
ATOM   6197  O  O     . ARG A 1 1078 ? 140.291 133.205 78.386  1.00 53.38  ? 1096 ARG A O     1 
ATOM   6198  C  CB    . ARG A 1 1078 ? 139.355 135.779 76.545  1.00 53.38  ? 1096 ARG A CB    1 
ATOM   6199  C  CG    . ARG A 1 1078 ? 138.267 136.693 76.019  1.00 53.38  ? 1096 ARG A CG    1 
ATOM   6200  C  CD    . ARG A 1 1078 ? 138.672 137.187 74.645  1.00 53.38  ? 1096 ARG A CD    1 
ATOM   6201  N  NE    . ARG A 1 1078 ? 137.663 138.015 74.000  1.00 53.38  ? 1096 ARG A NE    1 
ATOM   6202  C  CZ    . ARG A 1 1078 ? 137.838 138.608 72.828  1.00 53.38  ? 1096 ARG A CZ    1 
ATOM   6203  N  NH1   . ARG A 1 1078 ? 138.969 138.484 72.153  1.00 53.38  ? 1096 ARG A NH1   1 
ATOM   6204  N  NH2   . ARG A 1 1078 ? 136.856 139.346 72.320  1.00 53.38  ? 1096 ARG A NH2   1 
ATOM   6205  N  N     . VAL A 1 1079 ? 141.510 135.076 78.703  1.00 43.44  ? 1097 VAL A N     1 
ATOM   6206  C  CA    . VAL A 1 1079 ? 142.700 134.320 79.083  1.00 43.44  ? 1097 VAL A CA    1 
ATOM   6207  C  C     . VAL A 1 1079 ? 142.445 133.532 80.361  1.00 43.44  ? 1097 VAL A C     1 
ATOM   6208  O  O     . VAL A 1 1079 ? 142.847 132.369 80.481  1.00 43.44  ? 1097 VAL A O     1 
ATOM   6209  C  CB    . VAL A 1 1079 ? 143.911 135.260 79.218  1.00 43.44  ? 1097 VAL A CB    1 
ATOM   6210  C  CG1   . VAL A 1 1079 ? 145.126 134.490 79.696  1.00 43.44  ? 1097 VAL A CG1   1 
ATOM   6211  C  CG2   . VAL A 1 1079 ? 144.206 135.928 77.888  1.00 43.44  ? 1097 VAL A CG2   1 
ATOM   6212  N  N     . ASN A 1 1080 ? 141.776 134.151 81.338  1.00 38.12  ? 1098 ASN A N     1 
ATOM   6213  C  CA    . ASN A 1 1080 ? 141.391 133.428 82.544  1.00 38.12  ? 1098 ASN A CA    1 
ATOM   6214  C  C     . ASN A 1 1080 ? 140.444 132.283 82.219  1.00 38.12  ? 1098 ASN A C     1 
ATOM   6215  O  O     . ASN A 1 1080 ? 140.553 131.193 82.799  1.00 38.12  ? 1098 ASN A O     1 
ATOM   6216  C  CB    . ASN A 1 1080 ? 140.745 134.386 83.545  1.00 38.12  ? 1098 ASN A CB    1 
ATOM   6217  C  CG    . ASN A 1 1080 ? 139.936 133.664 84.605  1.00 38.12  ? 1098 ASN A CG    1 
ATOM   6218  O  OD1   . ASN A 1 1080 ? 138.731 133.465 84.454  1.00 38.12  ? 1098 ASN A OD1   1 
ATOM   6219  N  ND2   . ASN A 1 1080 ? 140.595 133.269 85.687  1.00 38.12  ? 1098 ASN A ND2   1 
ATOM   6220  N  N     . TRP A 1 1081 ? 139.497 132.517 81.308  1.00 33.62  ? 1099 TRP A N     1 
ATOM   6221  C  CA    . TRP A 1 1081 ? 138.527 131.486 80.976  1.00 33.62  ? 1099 TRP A CA    1 
ATOM   6222  C  C     . TRP A 1 1081 ? 139.205 130.268 80.379  1.00 33.62  ? 1099 TRP A C     1 
ATOM   6223  O  O     . TRP A 1 1081 ? 138.824 129.137 80.682  1.00 33.62  ? 1099 TRP A O     1 
ATOM   6224  C  CB    . TRP A 1 1081 ? 137.474 132.024 80.011  1.00 33.62  ? 1099 TRP A CB    1 
ATOM   6225  C  CG    . TRP A 1 1081 ? 136.631 130.935 79.426  1.00 33.62  ? 1099 TRP A CG    1 
ATOM   6226  C  CD1   . TRP A 1 1081 ? 135.486 130.415 79.947  1.00 33.62  ? 1099 TRP A CD1   1 
ATOM   6227  C  CD2   . TRP A 1 1081 ? 136.879 130.220 78.210  1.00 33.62  ? 1099 TRP A CD2   1 
ATOM   6228  N  NE1   . TRP A 1 1081 ? 135.000 129.424 79.130  1.00 33.62  ? 1099 TRP A NE1   1 
ATOM   6229  C  CE2   . TRP A 1 1081 ? 135.839 129.284 78.056  1.00 33.62  ? 1099 TRP A CE2   1 
ATOM   6230  C  CE3   . TRP A 1 1081 ? 137.879 130.282 77.236  1.00 33.62  ? 1099 TRP A CE3   1 
ATOM   6231  C  CZ2   . TRP A 1 1081 ? 135.770 128.420 76.968  1.00 33.62  ? 1099 TRP A CZ2   1 
ATOM   6232  C  CZ3   . TRP A 1 1081 ? 137.810 129.425 76.160  1.00 33.62  ? 1099 TRP A CZ3   1 
ATOM   6233  C  CH2   . TRP A 1 1081 ? 136.763 128.507 76.032  1.00 33.62  ? 1099 TRP A CH2   1 
ATOM   6234  N  N     . VAL A 1 1082 ? 140.212 130.474 79.529  1.00 32.71  ? 1100 VAL A N     1 
ATOM   6235  C  CA    . VAL A 1 1082 ? 140.852 129.330 78.880  1.00 32.71  ? 1100 VAL A CA    1 
ATOM   6236  C  C     . VAL A 1 1082 ? 141.395 128.363 79.926  1.00 32.71  ? 1100 VAL A C     1 
ATOM   6237  O  O     . VAL A 1 1082 ? 141.048 127.175 79.939  1.00 32.71  ? 1100 VAL A O     1 
ATOM   6238  C  CB    . VAL A 1 1082 ? 141.962 129.796 77.923  1.00 32.71  ? 1100 VAL A CB    1 
ATOM   6239  C  CG1   . VAL A 1 1082 ? 142.682 128.594 77.352  1.00 32.71  ? 1100 VAL A CG1   1 
ATOM   6240  C  CG2   . VAL A 1 1082 ? 141.381 130.643 76.810  1.00 32.71  ? 1100 VAL A CG2   1 
ATOM   6241  N  N     . VAL A 1 1083 ? 142.193 128.876 80.865  1.00 31.07  ? 1101 VAL A N     1 
ATOM   6242  C  CA    . VAL A 1 1083 ? 142.829 128.016 81.857  1.00 31.07  ? 1101 VAL A CA    1 
ATOM   6243  C  C     . VAL A 1 1083 ? 141.804 127.465 82.839  1.00 31.07  ? 1101 VAL A C     1 
ATOM   6244  O  O     . VAL A 1 1083 ? 141.828 126.275 83.177  1.00 31.07  ? 1101 VAL A O     1 
ATOM   6245  C  CB    . VAL A 1 1083 ? 143.950 128.777 82.586  1.00 31.07  ? 1101 VAL A CB    1 
ATOM   6246  C  CG1   . VAL A 1 1083 ? 144.559 127.904 83.669  1.00 31.07  ? 1101 VAL A CG1   1 
ATOM   6247  C  CG2   . VAL A 1 1083 ? 145.010 129.223 81.601  1.00 31.07  ? 1101 VAL A CG2   1 
ATOM   6248  N  N     . GLN A 1 1084 ? 140.888 128.309 83.320  1.00 31.14  ? 1102 GLN A N     1 
ATOM   6249  C  CA    . GLN A 1 1084 ? 139.960 127.845 84.344  1.00 31.14  ? 1102 GLN A CA    1 
ATOM   6250  C  C     . GLN A 1 1084 ? 138.947 126.855 83.779  1.00 31.14  ? 1102 GLN A C     1 
ATOM   6251  O  O     . GLN A 1 1084 ? 138.562 125.896 84.458  1.00 31.14  ? 1102 GLN A O     1 
ATOM   6252  C  CB    . GLN A 1 1084 ? 139.270 129.038 84.996  1.00 31.14  ? 1102 GLN A CB    1 
ATOM   6253  C  CG    . GLN A 1 1084 ? 140.110 129.729 86.044  1.00 31.14  ? 1102 GLN A CG    1 
ATOM   6254  C  CD    . GLN A 1 1084 ? 139.265 130.349 87.132  1.00 31.14  ? 1102 GLN A CD    1 
ATOM   6255  O  OE1   . GLN A 1 1084 ? 139.291 129.909 88.281  1.00 31.14  ? 1102 GLN A OE1   1 
ATOM   6256  N  NE2   . GLN A 1 1084 ? 138.502 131.374 86.775  1.00 31.14  ? 1102 GLN A NE2   1 
ATOM   6257  N  N     . SER A 1 1085 ? 138.521 127.042 82.530  1.00 28.57  ? 1103 SER A N     1 
ATOM   6258  C  CA    . SER A 1 1085 ? 137.633 126.079 81.899  1.00 28.57  ? 1103 SER A CA    1 
ATOM   6259  C  C     . SER A 1 1085 ? 138.372 124.816 81.481  1.00 28.57  ? 1103 SER A C     1 
ATOM   6260  O  O     . SER A 1 1085 ? 137.768 123.742 81.448  1.00 28.57  ? 1103 SER A O     1 
ATOM   6261  C  CB    . SER A 1 1085 ? 136.940 126.713 80.696  1.00 28.57  ? 1103 SER A CB    1 
ATOM   6262  O  OG    . SER A 1 1085 ? 135.937 125.854 80.185  1.00 28.57  ? 1103 SER A OG    1 
ATOM   6263  N  N     . SER A 1 1086 ? 139.672 124.907 81.182  1.00 25.47  ? 1104 SER A N     1 
ATOM   6264  C  CA    . SER A 1 1086 ? 140.457 123.688 81.029  1.00 25.47  ? 1104 SER A CA    1 
ATOM   6265  C  C     . SER A 1 1086 ? 140.525 122.920 82.342  1.00 25.47  ? 1104 SER A C     1 
ATOM   6266  O  O     . SER A 1 1086 ? 140.480 121.687 82.352  1.00 25.47  ? 1104 SER A O     1 
ATOM   6267  C  CB    . SER A 1 1086 ? 141.859 124.021 80.525  1.00 25.47  ? 1104 SER A CB    1 
ATOM   6268  O  OG    . SER A 1 1086 ? 141.813 124.528 79.206  1.00 25.47  ? 1104 SER A OG    1 
ATOM   6269  N  N     . ALA A 1 1087 ? 140.644 123.635 83.462  1.00 23.79  ? 1105 ALA A N     1 
ATOM   6270  C  CA    . ALA A 1 1087 ? 140.606 122.978 84.765  1.00 23.79  ? 1105 ALA A CA    1 
ATOM   6271  C  C     . ALA A 1 1087 ? 139.247 122.336 85.021  1.00 23.79  ? 1105 ALA A C     1 
ATOM   6272  O  O     . ALA A 1 1087 ? 139.158 121.246 85.603  1.00 23.79  ? 1105 ALA A O     1 
ATOM   6273  C  CB    . ALA A 1 1087 ? 140.946 123.981 85.866  1.00 23.79  ? 1105 ALA A CB    1 
ATOM   6274  N  N     . VAL A 1 1088 ? 138.172 122.999 84.598  1.00 25.21  ? 1106 VAL A N     1 
ATOM   6275  C  CA    . VAL A 1 1088 ? 136.846 122.401 84.721  1.00 25.21  ? 1106 VAL A CA    1 
ATOM   6276  C  C     . VAL A 1 1088 ? 136.733 121.161 83.840  1.00 25.21  ? 1106 VAL A C     1 
ATOM   6277  O  O     . VAL A 1 1088 ? 136.090 120.174 84.213  1.00 25.21  ? 1106 VAL A O     1 
ATOM   6278  C  CB    . VAL A 1 1088 ? 135.760 123.440 84.390  1.00 25.21  ? 1106 VAL A CB    1 
ATOM   6279  C  CG1   . VAL A 1 1088 ? 134.390 122.801 84.445  1.00 25.21  ? 1106 VAL A CG1   1 
ATOM   6280  C  CG2   . VAL A 1 1088 ? 135.835 124.595 85.364  1.00 25.21  ? 1106 VAL A CG2   1 
ATOM   6281  N  N     . ASP A 1 1089 ? 137.358 121.188 82.662  1.00 27.04  ? 1107 ASP A N     1 
ATOM   6282  C  CA    . ASP A 1 1089 ? 137.399 120.002 81.810  1.00 27.04  ? 1107 ASP A CA    1 
ATOM   6283  C  C     . ASP A 1 1089 ? 138.195 118.882 82.466  1.00 27.04  ? 1107 ASP A C     1 
ATOM   6284  O  O     . ASP A 1 1089 ? 137.850 117.705 82.336  1.00 27.04  ? 1107 ASP A O     1 
ATOM   6285  C  CB    . ASP A 1 1089 ? 137.996 120.354 80.449  1.00 27.04  ? 1107 ASP A CB    1 
ATOM   6286  C  CG    . ASP A 1 1089 ? 137.097 121.260 79.634  1.00 27.04  ? 1107 ASP A CG    1 
ATOM   6287  O  OD1   . ASP A 1 1089 ? 136.013 121.633 80.128  1.00 27.04  ? 1107 ASP A OD1   1 
ATOM   6288  O  OD2   . ASP A 1 1089 ? 137.475 121.596 78.494  1.00 27.04  ? 1107 ASP A OD2   1 
ATOM   6289  N  N     . TYR A 1 1090 ? 139.283 119.236 83.150  1.00 26.84  ? 1108 TYR A N     1 
ATOM   6290  C  CA    . TYR A 1 1090 ? 140.039 118.268 83.938  1.00 26.84  ? 1108 TYR A CA    1 
ATOM   6291  C  C     . TYR A 1 1090 ? 139.143 117.611 84.978  1.00 26.84  ? 1108 TYR A C     1 
ATOM   6292  O  O     . TYR A 1 1090 ? 139.160 116.387 85.151  1.00 26.84  ? 1108 TYR A O     1 
ATOM   6293  C  CB    . TYR A 1 1090 ? 141.225 118.971 84.605  1.00 26.84  ? 1108 TYR A CB    1 
ATOM   6294  C  CG    . TYR A 1 1090 ? 142.245 118.069 85.269  1.00 26.84  ? 1108 TYR A CG    1 
ATOM   6295  C  CD1   . TYR A 1 1090 ? 141.933 117.356 86.417  1.00 26.84  ? 1108 TYR A CD1   1 
ATOM   6296  C  CD2   . TYR A 1 1090 ? 143.534 117.958 84.765  1.00 26.84  ? 1108 TYR A CD2   1 
ATOM   6297  C  CE1   . TYR A 1 1090 ? 142.859 116.543 87.026  1.00 26.84  ? 1108 TYR A CE1   1 
ATOM   6298  C  CE2   . TYR A 1 1090 ? 144.469 117.146 85.372  1.00 26.84  ? 1108 TYR A CE2   1 
ATOM   6299  C  CZ    . TYR A 1 1090 ? 144.122 116.441 86.502  1.00 26.84  ? 1108 TYR A CZ    1 
ATOM   6300  O  OH    . TYR A 1 1090 ? 145.039 115.629 87.122  1.00 26.84  ? 1108 TYR A OH    1 
ATOM   6301  N  N     . LEU A 1 1091 ? 138.356 118.420 85.687  1.00 23.27  ? 1109 LEU A N     1 
ATOM   6302  C  CA    . LEU A 1 1091 ? 137.439 117.874 86.682  1.00 23.27  ? 1109 LEU A CA    1 
ATOM   6303  C  C     . LEU A 1 1091 ? 136.388 116.981 86.034  1.00 23.27  ? 1109 LEU A C     1 
ATOM   6304  O  O     . LEU A 1 1091 ? 136.015 115.943 86.593  1.00 23.27  ? 1109 LEU A O     1 
ATOM   6305  C  CB    . LEU A 1 1091 ? 136.773 119.006 87.462  1.00 23.27  ? 1109 LEU A CB    1 
ATOM   6306  C  CG    . LEU A 1 1091 ? 135.661 118.597 88.428  1.00 23.27  ? 1109 LEU A CG    1 
ATOM   6307  C  CD1   . LEU A 1 1091 ? 136.167 117.587 89.443  1.00 23.27  ? 1109 LEU A CD1   1 
ATOM   6308  C  CD2   . LEU A 1 1091 ? 135.090 119.819 89.125  1.00 23.27  ? 1109 LEU A CD2   1 
ATOM   6309  N  N     . HIS A 1 1092 ? 135.890 117.373 84.860  1.00 23.13  ? 1110 HIS A N     1 
ATOM   6310  C  CA    . HIS A 1 1092 ? 134.913 116.547 84.157  1.00 23.13  ? 1110 HIS A CA    1 
ATOM   6311  C  C     . HIS A 1 1092 ? 135.515 115.206 83.758  1.00 23.13  ? 1110 HIS A C     1 
ATOM   6312  O  O     . HIS A 1 1092 ? 134.877 114.158 83.912  1.00 23.13  ? 1110 HIS A O     1 
ATOM   6313  C  CB    . HIS A 1 1092 ? 134.387 117.284 82.925  1.00 23.13  ? 1110 HIS A CB    1 
ATOM   6314  C  CG    . HIS A 1 1092 ? 133.569 118.495 83.244  1.00 23.13  ? 1110 HIS A CG    1 
ATOM   6315  N  ND1   . HIS A 1 1092 ? 132.963 118.685 84.467  1.00 23.13  ? 1110 HIS A ND1   1 
ATOM   6316  C  CD2   . HIS A 1 1092 ? 133.257 119.582 82.498  1.00 23.13  ? 1110 HIS A CD2   1 
ATOM   6317  C  CE1   . HIS A 1 1092 ? 132.313 119.835 84.461  1.00 23.13  ? 1110 HIS A CE1   1 
ATOM   6318  N  NE2   . HIS A 1 1092 ? 132.475 120.399 83.278  1.00 23.13  ? 1110 HIS A NE2   1 
ATOM   6319  N  N     . LEU A 1 1093 ? 136.747 115.223 83.243  1.00 24.40  ? 1111 LEU A N     1 
ATOM   6320  C  CA    . LEU A 1 1093 ? 137.433 113.983 82.896  1.00 24.40  ? 1111 LEU A CA    1 
ATOM   6321  C  C     . LEU A 1 1093 ? 137.634 113.109 84.124  1.00 24.40  ? 1111 LEU A C     1 
ATOM   6322  O  O     . LEU A 1 1093 ? 137.421 111.892 84.071  1.00 24.40  ? 1111 LEU A O     1 
ATOM   6323  C  CB    . LEU A 1 1093 ? 138.780 114.294 82.244  1.00 24.40  ? 1111 LEU A CB    1 
ATOM   6324  C  CG    . LEU A 1 1093 ? 138.798 115.012 80.897  1.00 24.40  ? 1111 LEU A CG    1 
ATOM   6325  C  CD1   . LEU A 1 1093 ? 140.175 115.583 80.625  1.00 24.40  ? 1111 LEU A CD1   1 
ATOM   6326  C  CD2   . LEU A 1 1093 ? 138.399 114.060 79.794  1.00 24.40  ? 1111 LEU A CD2   1 
ATOM   6327  N  N     . MET A 1 1094 ? 138.042 113.716 85.241  1.00 24.96  ? 1112 MET A N     1 
ATOM   6328  C  CA    . MET A 1 1094 ? 138.220 112.957 86.472  1.00 24.96  ? 1112 MET A CA    1 
ATOM   6329  C  C     . MET A 1 1094 ? 136.916 112.317 86.916  1.00 24.96  ? 1112 MET A C     1 
ATOM   6330  O  O     . MET A 1 1094 ? 136.893 111.143 87.294  1.00 24.96  ? 1112 MET A O     1 
ATOM   6331  C  CB    . MET A 1 1094 ? 138.763 113.853 87.582  1.00 24.96  ? 1112 MET A CB    1 
ATOM   6332  C  CG    . MET A 1 1094 ? 140.234 114.175 87.471  1.00 24.96  ? 1112 MET A CG    1 
ATOM   6333  S  SD    . MET A 1 1094 ? 140.912 114.671 89.062  1.00 24.96  ? 1112 MET A SD    1 
ATOM   6334  C  CE    . MET A 1 1094 ? 140.693 113.163 90.001  1.00 24.96  ? 1112 MET A CE    1 
ATOM   6335  N  N     . LEU A 1 1095 ? 135.817 113.072 86.877  1.00 21.11  ? 1113 LEU A N     1 
ATOM   6336  C  CA    . LEU A 1 1095 ? 134.541 112.529 87.326  1.00 21.11  ? 1113 LEU A CA    1 
ATOM   6337  C  C     . LEU A 1 1095 ? 134.061 111.409 86.413  1.00 21.11  ? 1113 LEU A C     1 
ATOM   6338  O  O     . LEU A 1 1095 ? 133.571 110.380 86.894  1.00 21.11  ? 1113 LEU A O     1 
ATOM   6339  C  CB    . LEU A 1 1095 ? 133.499 113.642 87.417  1.00 21.11  ? 1113 LEU A CB    1 
ATOM   6340  C  CG    . LEU A 1 1095 ? 133.708 114.643 88.556  1.00 21.11  ? 1113 LEU A CG    1 
ATOM   6341  C  CD1   . LEU A 1 1095 ? 132.700 115.774 88.480  1.00 21.11  ? 1113 LEU A CD1   1 
ATOM   6342  C  CD2   . LEU A 1 1095 ? 133.614 113.935 89.892  1.00 21.11  ? 1113 LEU A CD2   1 
ATOM   6343  N  N     . VAL A 1 1096 ? 134.214 111.575 85.096  1.00 23.41  ? 1114 VAL A N     1 
ATOM   6344  C  CA    . VAL A 1 1096 ? 133.806 110.526 84.164  1.00 23.41  ? 1114 VAL A CA    1 
ATOM   6345  C  C     . VAL A 1 1096 ? 134.625 109.261 84.394  1.00 23.41  ? 1114 VAL A C     1 
ATOM   6346  O  O     . VAL A 1 1096 ? 134.081 108.152 84.490  1.00 23.41  ? 1114 VAL A O     1 
ATOM   6347  C  CB    . VAL A 1 1096 ? 133.934 111.017 82.711  1.00 23.41  ? 1114 VAL A CB    1 
ATOM   6348  C  CG1   . VAL A 1 1096 ? 133.698 109.871 81.745  1.00 23.41  ? 1114 VAL A CG1   1 
ATOM   6349  C  CG2   . VAL A 1 1096 ? 132.961 112.145 82.443  1.00 23.41  ? 1114 VAL A CG2   1 
ATOM   6350  N  N     . ALA A 1 1097 ? 135.949 109.413 84.495  1.00 24.46  ? 1115 ALA A N     1 
ATOM   6351  C  CA    . ALA A 1 1097 ? 136.819 108.260 84.689  1.00 24.46  ? 1115 ALA A CA    1 
ATOM   6352  C  C     . ALA A 1 1097 ? 136.532 107.567 86.013  1.00 24.46  ? 1115 ALA A C     1 
ATOM   6353  O  O     . ALA A 1 1097 ? 136.509 106.334 86.084  1.00 24.46  ? 1115 ALA A O     1 
ATOM   6354  C  CB    . ALA A 1 1097 ? 138.282 108.691 84.616  1.00 24.46  ? 1115 ALA A CB    1 
ATOM   6355  N  N     . MET A 1 1098 ? 136.318 108.344 87.076  1.00 26.14  ? 1116 MET A N     1 
ATOM   6356  C  CA    . MET A 1 1098 ? 136.063 107.755 88.383  1.00 26.14  ? 1116 MET A CA    1 
ATOM   6357  C  C     . MET A 1 1098 ? 134.722 107.040 88.420  1.00 26.14  ? 1116 MET A C     1 
ATOM   6358  O  O     . MET A 1 1098 ? 134.608 105.973 89.029  1.00 26.14  ? 1116 MET A O     1 
ATOM   6359  C  CB    . MET A 1 1098 ? 136.129 108.829 89.463  1.00 26.14  ? 1116 MET A CB    1 
ATOM   6360  C  CG    . MET A 1 1098 ? 137.534 109.289 89.786  1.00 26.14  ? 1116 MET A CG    1 
ATOM   6361  S  SD    . MET A 1 1098 ? 138.490 108.016 90.623  1.00 26.14  ? 1116 MET A SD    1 
ATOM   6362  C  CE    . MET A 1 1098 ? 137.628 107.943 92.184  1.00 26.14  ? 1116 MET A CE    1 
ATOM   6363  N  N     . LYS A 1 1099 ? 133.695 107.601 87.779  1.00 28.42  ? 1117 LYS A N     1 
ATOM   6364  C  CA    . LYS A 1 1099 ? 132.420 106.896 87.724  1.00 28.42  ? 1117 LYS A CA    1 
ATOM   6365  C  C     . LYS A 1 1099 ? 132.543 105.609 86.920  1.00 28.42  ? 1117 LYS A C     1 
ATOM   6366  O  O     . LYS A 1 1099 ? 131.965 104.581 87.293  1.00 28.42  ? 1117 LYS A O     1 
ATOM   6367  C  CB    . LYS A 1 1099 ? 131.334 107.794 87.139  1.00 28.42  ? 1117 LYS A CB    1 
ATOM   6368  C  CG    . LYS A 1 1099 ? 129.953 107.165 87.188  1.00 28.42  ? 1117 LYS A CG    1 
ATOM   6369  C  CD    . LYS A 1 1099 ? 128.856 108.178 86.933  1.00 28.42  ? 1117 LYS A CD    1 
ATOM   6370  C  CE    . LYS A 1 1099 ? 127.490 107.520 87.014  1.00 28.42  ? 1117 LYS A CE    1 
ATOM   6371  N  NZ    . LYS A 1 1099 ? 127.268 106.864 88.333  1.00 28.42  ? 1117 LYS A NZ    1 
ATOM   6372  N  N     . TRP A 1 1100 ? 133.305 105.641 85.823  1.00 31.82  ? 1118 TRP A N     1 
ATOM   6373  C  CA    . TRP A 1 1100 ? 133.533 104.424 85.051  1.00 31.82  ? 1118 TRP A CA    1 
ATOM   6374  C  C     . TRP A 1 1100 ? 134.247 103.365 85.881  1.00 31.82  ? 1118 TRP A C     1 
ATOM   6375  O  O     . TRP A 1 1100 ? 133.865 102.189 85.865  1.00 31.82  ? 1118 TRP A O     1 
ATOM   6376  C  CB    . TRP A 1 1100 ? 134.334 104.748 83.793  1.00 31.82  ? 1118 TRP A CB    1 
ATOM   6377  C  CG    . TRP A 1 1100 ? 134.991 103.558 83.176  1.00 31.82  ? 1118 TRP A CG    1 
ATOM   6378  C  CD1   . TRP A 1 1100 ? 134.382 102.420 82.734  1.00 31.82  ? 1118 TRP A CD1   1 
ATOM   6379  C  CD2   . TRP A 1 1100 ? 136.387 103.395 82.912  1.00 31.82  ? 1118 TRP A CD2   1 
ATOM   6380  N  NE1   . TRP A 1 1100 ? 135.315 101.554 82.221  1.00 31.82  ? 1118 TRP A NE1   1 
ATOM   6381  C  CE2   . TRP A 1 1100 ? 136.555 102.130 82.317  1.00 31.82  ? 1118 TRP A CE2   1 
ATOM   6382  C  CE3   . TRP A 1 1100 ? 137.513 104.194 83.125  1.00 31.82  ? 1118 TRP A CE3   1 
ATOM   6383  C  CZ2   . TRP A 1 1100 ? 137.802 101.647 81.932  1.00 31.82  ? 1118 TRP A CZ2   1 
ATOM   6384  C  CZ3   . TRP A 1 1100 ? 138.748 103.713 82.742  1.00 31.82  ? 1118 TRP A CZ3   1 
ATOM   6385  C  CH2   . TRP A 1 1100 ? 138.884 102.452 82.153  1.00 31.82  ? 1118 TRP A CH2   1 
ATOM   6386  N  N     . LEU A 1 1101 ? 135.290 103.764 86.611  1.00 30.86  ? 1119 LEU A N     1 
ATOM   6387  C  CA    . LEU A 1 1101 ? 136.024 102.815 87.442  1.00 30.86  ? 1119 LEU A CA    1 
ATOM   6388  C  C     . LEU A 1 1101 ? 135.152 102.268 88.564  1.00 30.86  ? 1119 LEU A C     1 
ATOM   6389  O  O     . LEU A 1 1101 ? 135.225 101.079 88.889  1.00 30.86  ? 1119 LEU A O     1 
ATOM   6390  C  CB    . LEU A 1 1101 ? 137.280 103.475 88.006  1.00 30.86  ? 1119 LEU A CB    1 
ATOM   6391  C  CG    . LEU A 1 1101 ? 138.442 103.632 87.024  1.00 30.86  ? 1119 LEU A CG    1 
ATOM   6392  C  CD1   . LEU A 1 1101 ? 139.573 104.426 87.644  1.00 30.86  ? 1119 LEU A CD1   1 
ATOM   6393  C  CD2   . LEU A 1 1101 ? 138.936 102.270 86.570  1.00 30.86  ? 1119 LEU A CD2   1 
ATOM   6394  N  N     . PHE A 1 1102 ? 134.326 103.120 89.171  1.00 31.11  ? 1120 PHE A N     1 
ATOM   6395  C  CA    . PHE A 1 1102 ? 133.459 102.663 90.249  1.00 31.11  ? 1120 PHE A CA    1 
ATOM   6396  C  C     . PHE A 1 1102 ? 132.402 101.694 89.741  1.00 31.11  ? 1120 PHE A C     1 
ATOM   6397  O  O     . PHE A 1 1102 ? 132.093 100.702 90.409  1.00 31.11  ? 1120 PHE A O     1 
ATOM   6398  C  CB    . PHE A 1 1102 ? 132.808 103.859 90.939  1.00 31.11  ? 1120 PHE A CB    1 
ATOM   6399  C  CG    . PHE A 1 1102 ? 133.675 104.505 91.978  1.00 31.11  ? 1120 PHE A CG    1 
ATOM   6400  C  CD1   . PHE A 1 1102 ? 135.040 104.608 91.793  1.00 31.11  ? 1120 PHE A CD1   1 
ATOM   6401  C  CD2   . PHE A 1 1102 ? 133.121 105.017 93.137  1.00 31.11  ? 1120 PHE A CD2   1 
ATOM   6402  C  CE1   . PHE A 1 1102 ? 135.835 105.196 92.745  1.00 31.11  ? 1120 PHE A CE1   1 
ATOM   6403  C  CE2   . PHE A 1 1102 ? 133.915 105.613 94.091  1.00 31.11  ? 1120 PHE A CE2   1 
ATOM   6404  C  CZ    . PHE A 1 1102 ? 135.273 105.704 93.894  1.00 31.11  ? 1120 PHE A CZ    1 
ATOM   6405  N  N     . GLU A 1 1103 ? 131.837 101.959 88.562  1.00 40.72  ? 1121 GLU A N     1 
ATOM   6406  C  CA    . GLU A 1 1103 ? 130.791 101.083 88.046  1.00 40.72  ? 1121 GLU A CA    1 
ATOM   6407  C  C     . GLU A 1 1103 ? 131.361 99.771  87.521  1.00 40.72  ? 1121 GLU A C     1 
ATOM   6408  O  O     . GLU A 1 1103 ? 130.766 98.706  87.726  1.00 40.72  ? 1121 GLU A O     1 
ATOM   6409  C  CB    . GLU A 1 1103 ? 129.997 101.802 86.956  1.00 40.72  ? 1121 GLU A CB    1 
ATOM   6410  C  CG    . GLU A 1 1103 ? 129.007 102.818 87.498  1.00 40.72  ? 1121 GLU A CG    1 
ATOM   6411  C  CD    . GLU A 1 1103 ? 127.914 102.174 88.332  1.00 40.72  ? 1121 GLU A CD    1 
ATOM   6412  O  OE1   . GLU A 1 1103 ? 127.521 101.030 88.021  1.00 40.72  ? 1121 GLU A OE1   1 
ATOM   6413  O  OE2   . GLU A 1 1103 ? 127.450 102.811 89.301  1.00 40.72  ? 1121 GLU A OE2   1 
ATOM   6414  N  N     . GLU A 1 1104 ? 132.508 99.823  86.839  1.00 42.66  ? 1122 GLU A N     1 
ATOM   6415  C  CA    . GLU A 1 1104 ? 133.064 98.618  86.230  1.00 42.66  ? 1122 GLU A CA    1 
ATOM   6416  C  C     . GLU A 1 1104 ? 133.497 97.607  87.285  1.00 42.66  ? 1122 GLU A C     1 
ATOM   6417  O  O     . GLU A 1 1104 ? 133.164 96.420  87.196  1.00 42.66  ? 1122 GLU A O     1 
ATOM   6418  C  CB    . GLU A 1 1104 ? 134.237 98.986  85.322  1.00 42.66  ? 1122 GLU A CB    1 
ATOM   6419  C  CG    . GLU A 1 1104 ? 135.078 97.799  84.878  1.00 42.66  ? 1122 GLU A CG    1 
ATOM   6420  C  CD    . GLU A 1 1104 ? 134.275 96.753  84.126  1.00 42.66  ? 1122 GLU A CD    1 
ATOM   6421  O  OE1   . GLU A 1 1104 ? 133.338 97.129  83.390  1.00 42.66  ? 1122 GLU A OE1   1 
ATOM   6422  O  OE2   . GLU A 1 1104 ? 134.581 95.551  84.274  1.00 42.66  ? 1122 GLU A OE2   1 
ATOM   6423  N  N     . PHE A 1 1105 ? 134.237 98.058  88.294  1.00 41.26  ? 1123 PHE A N     1 
ATOM   6424  C  CA    . PHE A 1 1105 ? 134.801 97.170  89.301  1.00 41.26  ? 1123 PHE A CA    1 
ATOM   6425  C  C     . PHE A 1 1105 ? 133.952 97.075  90.559  1.00 41.26  ? 1123 PHE A C     1 
ATOM   6426  O  O     . PHE A 1 1105 ? 134.371 96.427  91.522  1.00 41.26  ? 1123 PHE A O     1 
ATOM   6427  C  CB    . PHE A 1 1105 ? 136.217 97.620  89.660  1.00 41.26  ? 1123 PHE A CB    1 
ATOM   6428  C  CG    . PHE A 1 1105 ? 137.170 97.569  88.506  1.00 41.26  ? 1123 PHE A CG    1 
ATOM   6429  C  CD1   . PHE A 1 1105 ? 137.545 96.354  87.957  1.00 41.26  ? 1123 PHE A CD1   1 
ATOM   6430  C  CD2   . PHE A 1 1105 ? 137.689 98.732  87.966  1.00 41.26  ? 1123 PHE A CD2   1 
ATOM   6431  C  CE1   . PHE A 1 1105 ? 138.420 96.301  86.893  1.00 41.26  ? 1123 PHE A CE1   1 
ATOM   6432  C  CE2   . PHE A 1 1105 ? 138.566 98.684  86.902  1.00 41.26  ? 1123 PHE A CE2   1 
ATOM   6433  C  CZ    . PHE A 1 1105 ? 138.932 97.467  86.365  1.00 41.26  ? 1123 PHE A CZ    1 
ATOM   6434  N  N     . ALA A 1 1106 ? 132.778 97.705  90.572  1.00 39.04  ? 1124 ALA A N     1 
ATOM   6435  C  CA    . ALA A 1 1106 ? 131.827 97.613  91.679  1.00 39.04  ? 1124 ALA A CA    1 
ATOM   6436  C  C     . ALA A 1 1106 ? 132.450 98.098  92.990  1.00 39.04  ? 1124 ALA A C     1 
ATOM   6437  O  O     . ALA A 1 1106 ? 132.577 97.356  93.966  1.00 39.04  ? 1124 ALA A O     1 
ATOM   6438  C  CB    . ALA A 1 1106 ? 131.286 96.186  91.817  1.00 39.04  ? 1124 ALA A CB    1 
ATOM   6439  N  N     . ILE A 1 1107 ? 132.840 99.368  92.992  1.00 31.13  ? 1125 ILE A N     1 
ATOM   6440  C  CA    . ILE A 1 1107 ? 133.315 100.036 94.198  1.00 31.13  ? 1125 ILE A CA    1 
ATOM   6441  C  C     . ILE A 1 1107 ? 132.137 100.746 94.851  1.00 31.13  ? 1125 ILE A C     1 
ATOM   6442  O  O     . ILE A 1 1107 ? 131.412 101.500 94.192  1.00 31.13  ? 1125 ILE A O     1 
ATOM   6443  C  CB    . ILE A 1 1107 ? 134.445 101.026 93.870  1.00 31.13  ? 1125 ILE A CB    1 
ATOM   6444  C  CG1   . ILE A 1 1107 ? 135.671 100.282 93.348  1.00 31.13  ? 1125 ILE A CG1   1 
ATOM   6445  C  CG2   . ILE A 1 1107 ? 134.808 101.850 95.091  1.00 31.13  ? 1125 ILE A CG2   1 
ATOM   6446  C  CD1   . ILE A 1 1107 ? 136.845 101.186 93.073  1.00 31.13  ? 1125 ILE A CD1   1 
ATOM   6447  N  N     . ASP A 1 1108 ? 131.929 100.494 96.144  1.00 30.20  ? 1126 ASP A N     1 
ATOM   6448  C  CA    . ASP A 1 1108 ? 130.812 101.096 96.876  1.00 30.20  ? 1126 ASP A CA    1 
ATOM   6449  C  C     . ASP A 1 1108 ? 131.185 102.486 97.296  1.00 30.20  ? 1126 ASP A C     1 
ATOM   6450  O  O     . ASP A 1 1108 ? 131.433 102.739 98.469  1.00 30.20  ? 1126 ASP A O     1 
ATOM   6451  C  CB    . ASP A 1 1108 ? 130.461 100.268 98.103  1.00 30.20  ? 1126 ASP A CB    1 
ATOM   6452  C  CG    . ASP A 1 1108 ? 130.576 98.776  97.858  1.00 30.20  ? 1126 ASP A CG    1 
ATOM   6453  O  OD1   . ASP A 1 1108 ? 130.718 98.365  96.688  1.00 30.20  ? 1126 ASP A OD1   1 
ATOM   6454  O  OD2   . ASP A 1 1108 ? 130.523 98.010  98.842  1.00 30.20  ? 1126 ASP A OD2   1 
ATOM   6455  N  N     . GLY A 1 1109 ? 131.217 103.398 96.350  1.00 25.81  ? 1127 GLY A N     1 
ATOM   6456  C  CA    . GLY A 1 1109 ? 131.614 104.766 96.601  1.00 25.81  ? 1127 GLY A CA    1 
ATOM   6457  C  C     . GLY A 1 1109 ? 130.593 105.749 96.065  1.00 25.81  ? 1127 GLY A C     1 
ATOM   6458  O  O     . GLY A 1 1109 ? 129.538 105.366 95.559  1.00 25.81  ? 1127 GLY A O     1 
ATOM   6459  N  N     . ARG A 1 1110 ? 130.939 107.029 96.182  1.00 18.99  ? 1128 ARG A N     1 
ATOM   6460  C  CA    . ARG A 1 1110 ? 130.077 108.127 95.774  1.00 18.99  ? 1128 ARG A CA    1 
ATOM   6461  C  C     . ARG A 1 1110 ? 130.895 109.406 95.785  1.00 18.99  ? 1128 ARG A C     1 
ATOM   6462  O  O     . ARG A 1 1110 ? 131.743 109.590 96.659  1.00 18.99  ? 1128 ARG A O     1 
ATOM   6463  C  CB    . ARG A 1 1110 ? 128.871 108.263 96.711  1.00 18.99  ? 1128 ARG A CB    1 
ATOM   6464  C  CG    . ARG A 1 1110 ? 128.003 109.470 96.426  1.00 18.99  ? 1128 ARG A CG    1 
ATOM   6465  C  CD    . ARG A 1 1110 ? 126.732 109.460 97.251  1.00 18.99  ? 1128 ARG A CD    1 
ATOM   6466  N  NE    . ARG A 1 1110 ? 125.830 110.528 96.840  1.00 18.99  ? 1128 ARG A NE    1 
ATOM   6467  C  CZ    . ARG A 1 1110 ? 124.565 110.627 97.222  1.00 18.99  ? 1128 ARG A CZ    1 
ATOM   6468  N  NH1   . ARG A 1 1110 ? 124.019 109.742 98.038  1.00 18.99  ? 1128 ARG A NH1   1 
ATOM   6469  N  NH2   . ARG A 1 1110 ? 123.827 111.636 96.768  1.00 18.99  ? 1128 ARG A NH2   1 
ATOM   6470  N  N     . PHE A 1 1111 ? 130.646 110.275 94.812  1.00 15.25  ? 1129 PHE A N     1 
ATOM   6471  C  CA    . PHE A 1 1111 ? 131.285 111.582 94.800  1.00 15.25  ? 1129 PHE A CA    1 
ATOM   6472  C  C     . PHE A 1 1111 ? 130.801 112.395 95.991  1.00 15.25  ? 1129 PHE A C     1 
ATOM   6473  O  O     . PHE A 1 1111 ? 129.596 112.486 96.244  1.00 15.25  ? 1129 PHE A O     1 
ATOM   6474  C  CB    . PHE A 1 1111 ? 130.974 112.304 93.492  1.00 15.25  ? 1129 PHE A CB    1 
ATOM   6475  C  CG    . PHE A 1 1111 ? 131.575 113.672 93.393  1.00 15.25  ? 1129 PHE A CG    1 
ATOM   6476  C  CD1   . PHE A 1 1111 ? 132.912 113.877 93.665  1.00 15.25  ? 1129 PHE A CD1   1 
ATOM   6477  C  CD2   . PHE A 1 1111 ? 130.804 114.750 93.003  1.00 15.25  ? 1129 PHE A CD2   1 
ATOM   6478  C  CE1   . PHE A 1 1111 ? 133.465 115.134 93.566  1.00 15.25  ? 1129 PHE A CE1   1 
ATOM   6479  C  CE2   . PHE A 1 1111 ? 131.353 116.009 92.901  1.00 15.25  ? 1129 PHE A CE2   1 
ATOM   6480  C  CZ    . PHE A 1 1111 ? 132.685 116.200 93.182  1.00 15.25  ? 1129 PHE A CZ    1 
ATOM   6481  N  N     . CYS A 1 1112 ? 131.739 112.981 96.732  1.00 15.76  ? 1130 CYS A N     1 
ATOM   6482  C  CA    . CYS A 1 1112 ? 131.400 113.733 97.934  1.00 15.76  ? 1130 CYS A CA    1 
ATOM   6483  C  C     . CYS A 1 1112 ? 131.369 115.235 97.676  1.00 15.76  ? 1130 CYS A C     1 
ATOM   6484  O  O     . CYS A 1 1112 ? 130.329 115.876 97.849  1.00 15.76  ? 1130 CYS A O     1 
ATOM   6485  C  CB    . CYS A 1 1112 ? 132.398 113.401 99.050  1.00 15.76  ? 1130 CYS A CB    1 
ATOM   6486  S  SG    . CYS A 1 1112 ? 132.185 114.368 100.551 1.00 15.76  ? 1130 CYS A SG    1 
ATOM   6487  N  N     . ILE A 1 1113 ? 132.495 115.808 97.252  1.00 15.80  ? 1131 ILE A N     1 
ATOM   6488  C  CA    . ILE A 1 1113 ? 132.558 117.220 96.897  1.00 15.80  ? 1131 ILE A CA    1 
ATOM   6489  C  C     . ILE A 1 1113 ? 133.843 117.440 96.120  1.00 15.80  ? 1131 ILE A C     1 
ATOM   6490  O  O     . ILE A 1 1113 ? 134.762 116.617 96.178  1.00 15.80  ? 1131 ILE A O     1 
ATOM   6491  C  CB    . ILE A 1 1113 ? 132.489 118.112 98.165  1.00 15.80  ? 1131 ILE A CB    1 
ATOM   6492  C  CG1   . ILE A 1 1113 ? 132.081 119.540 97.791  1.00 15.80  ? 1131 ILE A CG1   1 
ATOM   6493  C  CG2   . ILE A 1 1113 ? 133.819 118.109 98.888  1.00 15.80  ? 1131 ILE A CG2   1 
ATOM   6494  C  CD1   . ILE A 1 1113 ? 131.795 120.437 98.973  1.00 15.80  ? 1131 ILE A CD1   1 
ATOM   6495  N  N     . SER A 1 1114 ? 133.902 118.535 95.371  1.00 18.81  ? 1132 SER A N     1 
ATOM   6496  C  CA    . SER A 1 1114 ? 135.132 118.959 94.706  1.00 18.81  ? 1132 SER A CA    1 
ATOM   6497  C  C     . SER A 1 1114 ? 135.366 120.414 95.090  1.00 18.81  ? 1132 SER A C     1 
ATOM   6498  O  O     . SER A 1 1114 ? 134.977 121.332 94.368  1.00 18.81  ? 1132 SER A O     1 
ATOM   6499  C  CB    . SER A 1 1114 ? 135.044 118.773 93.200  1.00 18.81  ? 1132 SER A CB    1 
ATOM   6500  O  OG    . SER A 1 1114 ? 134.222 119.765 92.618  1.00 18.81  ? 1132 SER A OG    1 
ATOM   6501  N  N     . ILE A 1 1115 ? 136.020 120.616 96.231  1.00 26.46  ? 1133 ILE A N     1 
ATOM   6502  C  CA    . ILE A 1 1115 ? 136.340 121.955 96.717  1.00 26.46  ? 1133 ILE A CA    1 
ATOM   6503  C  C     . ILE A 1 1115 ? 137.584 122.414 95.967  1.00 26.46  ? 1133 ILE A C     1 
ATOM   6504  O  O     . ILE A 1 1115 ? 138.700 122.004 96.288  1.00 26.46  ? 1133 ILE A O     1 
ATOM   6505  C  CB    . ILE A 1 1115 ? 136.554 121.978 98.231  1.00 26.46  ? 1133 ILE A CB    1 
ATOM   6506  C  CG1   . ILE A 1 1115 ? 135.314 121.449 98.949  1.00 26.46  ? 1133 ILE A CG1   1 
ATOM   6507  C  CG2   . ILE A 1 1115 ? 136.897 123.387 98.694  1.00 26.46  ? 1133 ILE A CG2   1 
ATOM   6508  C  CD1   . ILE A 1 1115 ? 135.484 121.339 100.444 1.00 26.46  ? 1133 ILE A CD1   1 
ATOM   6509  N  N     . HIS A 1 1116 ? 137.392 123.266 94.961  1.00 35.95  ? 1134 HIS A N     1 
ATOM   6510  C  CA    . HIS A 1 1116 ? 138.464 123.726 94.075  1.00 35.95  ? 1134 HIS A CA    1 
ATOM   6511  C  C     . HIS A 1 1116 ? 139.053 122.494 93.399  1.00 35.95  ? 1134 HIS A C     1 
ATOM   6512  O  O     . HIS A 1 1116 ? 138.305 121.779 92.709  1.00 35.95  ? 1134 HIS A O     1 
ATOM   6513  C  CB    . HIS A 1 1116 ? 139.448 124.591 94.865  1.00 35.95  ? 1134 HIS A CB    1 
ATOM   6514  C  CG    . HIS A 1 1116 ? 138.834 125.829 95.441  1.00 35.95  ? 1134 HIS A CG    1 
ATOM   6515  N  ND1   . HIS A 1 1116 ? 138.785 127.024 94.756  1.00 35.95  ? 1134 HIS A ND1   1 
ATOM   6516  C  CD2   . HIS A 1 1116 ? 138.245 126.057 96.638  1.00 35.95  ? 1134 HIS A CD2   1 
ATOM   6517  C  CE1   . HIS A 1 1116 ? 138.191 127.935 95.506  1.00 35.95  ? 1134 HIS A CE1   1 
ATOM   6518  N  NE2   . HIS A 1 1116 ? 137.854 127.375 96.653  1.00 35.95  ? 1134 HIS A NE2   1 
ATOM   6519  N  N     . ASP A 1 1117 ? 140.343 122.197 93.559  1.00 34.99  ? 1135 ASP A N     1 
ATOM   6520  C  CA    . ASP A 1 1117 ? 140.950 121.056 92.889  1.00 34.99  ? 1135 ASP A CA    1 
ATOM   6521  C  C     . ASP A 1 1117 ? 140.812 119.754 93.663  1.00 34.99  ? 1135 ASP A C     1 
ATOM   6522  O  O     . ASP A 1 1117 ? 141.020 118.684 93.082  1.00 34.99  ? 1135 ASP A O     1 
ATOM   6523  C  CB    . ASP A 1 1117 ? 142.431 121.331 92.621  1.00 34.99  ? 1135 ASP A CB    1 
ATOM   6524  C  CG    . ASP A 1 1117 ? 143.168 121.797 93.854  1.00 34.99  ? 1135 ASP A CG    1 
ATOM   6525  O  OD1   . ASP A 1 1117 ? 142.534 121.906 94.923  1.00 34.99  ? 1135 ASP A OD1   1 
ATOM   6526  O  OD2   . ASP A 1 1117 ? 144.384 122.057 93.751  1.00 34.99  ? 1135 ASP A OD2   1 
ATOM   6527  N  N     . GLU A 1 1118 ? 140.466 119.809 94.945  1.00 26.37  ? 1136 GLU A N     1 
ATOM   6528  C  CA    . GLU A 1 1118 ? 140.286 118.585 95.710  1.00 26.37  ? 1136 GLU A CA    1 
ATOM   6529  C  C     . GLU A 1 1118 ? 139.142 117.763 95.135  1.00 26.37  ? 1136 GLU A C     1 
ATOM   6530  O  O     . GLU A 1 1118 ? 138.188 118.296 94.568  1.00 26.37  ? 1136 GLU A O     1 
ATOM   6531  C  CB    . GLU A 1 1118 ? 140.008 118.900 97.178  1.00 26.37  ? 1136 GLU A CB    1 
ATOM   6532  C  CG    . GLU A 1 1118 ? 141.182 119.506 97.916  1.00 26.37  ? 1136 GLU A CG    1 
ATOM   6533  C  CD    . GLU A 1 1118 ? 140.981 119.500 99.416  1.00 26.37  ? 1136 GLU A CD    1 
ATOM   6534  O  OE1   . GLU A 1 1118 ? 140.036 118.832 99.887  1.00 26.37  ? 1136 GLU A OE1   1 
ATOM   6535  O  OE2   . GLU A 1 1118 ? 141.766 120.161 100.125 1.00 26.37  ? 1136 GLU A OE2   1 
ATOM   6536  N  N     . VAL A 1 1119 ? 139.260 116.447 95.261  1.00 17.99  ? 1137 VAL A N     1 
ATOM   6537  C  CA    . VAL A 1 1119 ? 138.222 115.516 94.842  1.00 17.99  ? 1137 VAL A CA    1 
ATOM   6538  C  C     . VAL A 1 1119 ? 138.093 114.462 95.927  1.00 17.99  ? 1137 VAL A C     1 
ATOM   6539  O  O     . VAL A 1 1119 ? 138.999 113.642 96.107  1.00 17.99  ? 1137 VAL A O     1 
ATOM   6540  C  CB    . VAL A 1 1119 ? 138.541 114.860 93.489  1.00 17.99  ? 1137 VAL A CB    1 
ATOM   6541  C  CG1   . VAL A 1 1119 ? 137.488 113.828 93.152  1.00 17.99  ? 1137 VAL A CG1   1 
ATOM   6542  C  CG2   . VAL A 1 1119 ? 138.631 115.908 92.390  1.00 17.99  ? 1137 VAL A CG2   1 
ATOM   6543  N  N     . ARG A 1 1120 ? 136.976 114.476 96.641  1.00 14.55  ? 1138 ARG A N     1 
ATOM   6544  C  CA    . ARG A 1 1120 ? 136.756 113.575 97.759  1.00 14.55  ? 1138 ARG A CA    1 
ATOM   6545  C  C     . ARG A 1 1120 ? 135.681 112.569 97.393  1.00 14.55  ? 1138 ARG A C     1 
ATOM   6546  O  O     . ARG A 1 1120 ? 134.699 112.910 96.730  1.00 14.55  ? 1138 ARG A O     1 
ATOM   6547  C  CB    . ARG A 1 1120 ? 136.344 114.342 99.011  1.00 14.55  ? 1138 ARG A CB    1 
ATOM   6548  C  CG    . ARG A 1 1120 ? 137.294 115.459 99.383  1.00 14.55  ? 1138 ARG A CG    1 
ATOM   6549  C  CD    . ARG A 1 1120 ? 138.531 114.917 100.064 1.00 14.55  ? 1138 ARG A CD    1 
ATOM   6550  N  NE    . ARG A 1 1120 ? 139.602 115.903 100.118 1.00 14.55  ? 1138 ARG A NE    1 
ATOM   6551  C  CZ    . ARG A 1 1120 ? 140.740 115.732 100.775 1.00 14.55  ? 1138 ARG A CZ    1 
ATOM   6552  N  NH1   . ARG A 1 1120 ? 140.973 114.636 101.477 1.00 14.55  ? 1138 ARG A NH1   1 
ATOM   6553  N  NH2   . ARG A 1 1120 ? 141.666 116.684 100.726 1.00 14.55  ? 1138 ARG A NH2   1 
ATOM   6554  N  N     . TYR A 1 1121 ? 135.868 111.332 97.829  1.00 16.77  ? 1139 TYR A N     1 
ATOM   6555  C  CA    . TYR A 1 1121 ? 134.912 110.270 97.568  1.00 16.77  ? 1139 TYR A CA    1 
ATOM   6556  C  C     . TYR A 1 1121 ? 134.545 109.585 98.871  1.00 16.77  ? 1139 TYR A C     1 
ATOM   6557  O  O     . TYR A 1 1121 ? 135.402 109.363 99.729  1.00 16.77  ? 1139 TYR A O     1 
ATOM   6558  C  CB    . TYR A 1 1121 ? 135.470 109.263 96.562  1.00 16.77  ? 1139 TYR A CB    1 
ATOM   6559  C  CG    . TYR A 1 1121 ? 135.166 109.639 95.134  1.00 16.77  ? 1139 TYR A CG    1 
ATOM   6560  C  CD1   . TYR A 1 1121 ? 136.000 110.490 94.426  1.00 16.77  ? 1139 TYR A CD1   1 
ATOM   6561  C  CD2   . TYR A 1 1121 ? 134.030 109.160 94.503  1.00 16.77  ? 1139 TYR A CD2   1 
ATOM   6562  C  CE1   . TYR A 1 1121 ? 135.714 110.841 93.125  1.00 16.77  ? 1139 TYR A CE1   1 
ATOM   6563  C  CE2   . TYR A 1 1121 ? 133.737 109.506 93.206  1.00 16.77  ? 1139 TYR A CE2   1 
ATOM   6564  C  CZ    . TYR A 1 1121 ? 134.581 110.345 92.522  1.00 16.77  ? 1139 TYR A CZ    1 
ATOM   6565  O  OH    . TYR A 1 1121 ? 134.284 110.690 91.226  1.00 16.77  ? 1139 TYR A OH    1 
ATOM   6566  N  N     . LEU A 1 1122 ? 133.264 109.255 99.012  1.00 18.27  ? 1140 LEU A N     1 
ATOM   6567  C  CA    . LEU A 1 1122 ? 132.735 108.650 100.232 1.00 18.27  ? 1140 LEU A CA    1 
ATOM   6568  C  C     . LEU A 1 1122 ? 132.723 107.136 100.047 1.00 18.27  ? 1140 LEU A C     1 
ATOM   6569  O  O     . LEU A 1 1122 ? 131.680 106.504 99.887  1.00 18.27  ? 1140 LEU A O     1 
ATOM   6570  C  CB    . LEU A 1 1122 ? 131.349 109.201 100.536 1.00 18.27  ? 1140 LEU A CB    1 
ATOM   6571  C  CG    . LEU A 1 1122 ? 130.684 108.775 101.840 1.00 18.27  ? 1140 LEU A CG    1 
ATOM   6572  C  CD1   . LEU A 1 1122 ? 131.521 109.205 103.026 1.00 18.27  ? 1140 LEU A CD1   1 
ATOM   6573  C  CD2   . LEU A 1 1122 ? 129.296 109.370 101.916 1.00 18.27  ? 1140 LEU A CD2   1 
ATOM   6574  N  N     . VAL A 1 1123 ? 133.908 106.554 100.070 1.00 21.06  ? 1141 VAL A N     1 
ATOM   6575  C  CA    . VAL A 1 1123 ? 134.072 105.134 99.791  1.00 21.06  ? 1141 VAL A CA    1 
ATOM   6576  C  C     . VAL A 1 1123 ? 133.978 104.349 101.088 1.00 21.06  ? 1141 VAL A C     1 
ATOM   6577  O  O     . VAL A 1 1123 ? 134.343 104.831 102.163 1.00 21.06  ? 1141 VAL A O     1 
ATOM   6578  C  CB    . VAL A 1 1123 ? 135.409 104.868 99.075  1.00 21.06  ? 1141 VAL A CB    1 
ATOM   6579  C  CG1   . VAL A 1 1123 ? 135.348 103.546 98.330  1.00 21.06  ? 1141 VAL A CG1   1 
ATOM   6580  C  CG2   . VAL A 1 1123 ? 135.734 106.010 98.140  1.00 21.06  ? 1141 VAL A CG2   1 
ATOM   6581  N  N     . ARG A 1 1124 ? 133.480 103.121 100.985 1.00 28.67  ? 1142 ARG A N     1 
ATOM   6582  C  CA    . ARG A 1 1124 ? 133.392 102.265 102.154 1.00 28.67  ? 1142 ARG A CA    1 
ATOM   6583  C  C     . ARG A 1 1124 ? 134.792 101.866 102.618 1.00 28.67  ? 1142 ARG A C     1 
ATOM   6584  O  O     . ARG A 1 1124 ? 135.764 101.912 101.859 1.00 28.67  ? 1142 ARG A O     1 
ATOM   6585  C  CB    . ARG A 1 1124 ? 132.545 101.032 101.852 1.00 28.67  ? 1142 ARG A CB    1 
ATOM   6586  C  CG    . ARG A 1 1124 ? 131.942 100.394 103.088 1.00 28.67  ? 1142 ARG A CG    1 
ATOM   6587  C  CD    . ARG A 1 1124 ? 130.844 99.420  102.724 1.00 28.67  ? 1142 ARG A CD    1 
ATOM   6588  N  NE    . ARG A 1 1124 ? 129.661 100.098 102.208 1.00 28.67  ? 1142 ARG A NE    1 
ATOM   6589  C  CZ    . ARG A 1 1124 ? 128.595 99.474  101.727 1.00 28.67  ? 1142 ARG A CZ    1 
ATOM   6590  N  NH1   . ARG A 1 1124 ? 128.534 98.154  101.671 1.00 28.67  ? 1142 ARG A NH1   1 
ATOM   6591  N  NH2   . ARG A 1 1124 ? 127.565 100.192 101.287 1.00 28.67  ? 1142 ARG A NH2   1 
ATOM   6592  N  N     . GLU A 1 1125 ? 134.884 101.479 103.893 1.00 35.52  ? 1143 GLU A N     1 
ATOM   6593  C  CA    . GLU A 1 1125 ? 136.186 101.307 104.532 1.00 35.52  ? 1143 GLU A CA    1 
ATOM   6594  C  C     . GLU A 1 1125 ? 137.000 100.200 103.874 1.00 35.52  ? 1143 GLU A C     1 
ATOM   6595  O  O     . GLU A 1 1125 ? 138.217 100.333 103.707 1.00 35.52  ? 1143 GLU A O     1 
ATOM   6596  C  CB    . GLU A 1 1125 ? 136.000 101.025 106.022 1.00 35.52  ? 1143 GLU A CB    1 
ATOM   6597  C  CG    . GLU A 1 1125 ? 137.130 101.545 106.890 1.00 35.52  ? 1143 GLU A CG    1 
ATOM   6598  C  CD    . GLU A 1 1125 ? 136.736 101.669 108.348 1.00 35.52  ? 1143 GLU A CD    1 
ATOM   6599  O  OE1   . GLU A 1 1125 ? 135.954 100.824 108.832 1.00 35.52  ? 1143 GLU A OE1   1 
ATOM   6600  O  OE2   . GLU A 1 1125 ? 137.203 102.621 109.009 1.00 35.52  ? 1143 GLU A OE2   1 
ATOM   6601  N  N     . GLU A 1 1126 ? 136.351 99.094  103.507 1.00 33.39  ? 1144 GLU A N     1 
ATOM   6602  C  CA    . GLU A 1 1126 ? 137.074 97.984  102.895 1.00 33.39  ? 1144 GLU A CA    1 
ATOM   6603  C  C     . GLU A 1 1126 ? 137.691 98.391  101.564 1.00 33.39  ? 1144 GLU A C     1 
ATOM   6604  O  O     . GLU A 1 1126 ? 138.791 97.946  101.218 1.00 33.39  ? 1144 GLU A O     1 
ATOM   6605  C  CB    . GLU A 1 1126 ? 136.143 96.789  102.700 1.00 33.39  ? 1144 GLU A CB    1 
ATOM   6606  C  CG    . GLU A 1 1126 ? 135.144 96.590  103.821 1.00 33.39  ? 1144 GLU A CG    1 
ATOM   6607  C  CD    . GLU A 1 1126 ? 133.865 97.365  103.594 1.00 33.39  ? 1144 GLU A CD    1 
ATOM   6608  O  OE1   . GLU A 1 1126 ? 133.529 97.624  102.420 1.00 33.39  ? 1144 GLU A OE1   1 
ATOM   6609  O  OE2   . GLU A 1 1126 ? 133.201 97.722  104.589 1.00 33.39  ? 1144 GLU A OE2   1 
ATOM   6610  N  N     . ASP A 1 1127 ? 136.998 99.234  100.805 1.00 31.63  ? 1145 ASP A N     1 
ATOM   6611  C  CA    . ASP A 1 1127 ? 137.426 99.624  99.471  1.00 31.63  ? 1145 ASP A CA    1 
ATOM   6612  C  C     . ASP A 1 1127 ? 138.341 100.840 99.472  1.00 31.63  ? 1145 ASP A C     1 
ATOM   6613  O  O     . ASP A 1 1127 ? 138.610 101.392 98.402  1.00 31.63  ? 1145 ASP A O     1 
ATOM   6614  C  CB    . ASP A 1 1127 ? 136.205 99.897  98.593  1.00 31.63  ? 1145 ASP A CB    1 
ATOM   6615  C  CG    . ASP A 1 1127 ? 135.192 98.774  98.644  1.00 31.63  ? 1145 ASP A CG    1 
ATOM   6616  O  OD1   . ASP A 1 1127 ? 135.604 97.609  98.822  1.00 31.63  ? 1145 ASP A OD1   1 
ATOM   6617  O  OD2   . ASP A 1 1127 ? 133.983 99.053  98.514  1.00 31.63  ? 1145 ASP A OD2   1 
ATOM   6618  N  N     . ARG A 1 1128 ? 138.826 101.270 100.639 1.00 33.97  ? 1146 ARG A N     1 
ATOM   6619  C  CA    . ARG A 1 1128 ? 139.652 102.470 100.700 1.00 33.97  ? 1146 ARG A CA    1 
ATOM   6620  C  C     . ARG A 1 1128 ? 140.950 102.324 99.917  1.00 33.97  ? 1146 ARG A C     1 
ATOM   6621  O  O     . ARG A 1 1128 ? 141.513 103.334 99.484  1.00 33.97  ? 1146 ARG A O     1 
ATOM   6622  C  CB    . ARG A 1 1128 ? 139.962 102.826 102.155 1.00 33.97  ? 1146 ARG A CB    1 
ATOM   6623  C  CG    . ARG A 1 1128 ? 140.849 101.821 102.876 1.00 33.97  ? 1146 ARG A CG    1 
ATOM   6624  C  CD    . ARG A 1 1128 ? 140.996 102.165 104.352 1.00 33.97  ? 1146 ARG A CD    1 
ATOM   6625  N  NE    . ARG A 1 1128 ? 141.670 101.109 105.096 1.00 33.97  ? 1146 ARG A NE    1 
ATOM   6626  C  CZ    . ARG A 1 1128 ? 141.060 100.049 105.609 1.00 33.97  ? 1146 ARG A CZ    1 
ATOM   6627  N  NH1   . ARG A 1 1128 ? 139.756 99.870  105.475 1.00 33.97  ? 1146 ARG A NH1   1 
ATOM   6628  N  NH2   . ARG A 1 1128 ? 141.775 99.146  106.271 1.00 33.97  ? 1146 ARG A NH2   1 
ATOM   6629  N  N     . TYR A 1 1129 ? 141.435 101.097 99.722  1.00 37.22  ? 1147 TYR A N     1 
ATOM   6630  C  CA    . TYR A 1 1129 ? 142.648 100.872 98.945  1.00 37.22  ? 1147 TYR A CA    1 
ATOM   6631  C  C     . TYR A 1 1129 ? 142.344 100.629 97.475  1.00 37.22  ? 1147 TYR A C     1 
ATOM   6632  O  O     . TYR A 1 1129 ? 143.086 101.093 96.602  1.00 37.22  ? 1147 TYR A O     1 
ATOM   6633  C  CB    . TYR A 1 1129 ? 143.430 99.690  99.517  1.00 37.22  ? 1147 TYR A CB    1 
ATOM   6634  C  CG    . TYR A 1 1129 ? 143.749 99.841  100.982 1.00 37.22  ? 1147 TYR A CG    1 
ATOM   6635  C  CD1   . TYR A 1 1129 ? 144.605 100.837 101.421 1.00 37.22  ? 1147 TYR A CD1   1 
ATOM   6636  C  CD2   . TYR A 1 1129 ? 143.195 98.990  101.926 1.00 37.22  ? 1147 TYR A CD2   1 
ATOM   6637  C  CE1   . TYR A 1 1129 ? 144.900 100.986 102.757 1.00 37.22  ? 1147 TYR A CE1   1 
ATOM   6638  C  CE2   . TYR A 1 1129 ? 143.486 99.129  103.265 1.00 37.22  ? 1147 TYR A CE2   1 
ATOM   6639  C  CZ    . TYR A 1 1129 ? 144.339 100.129 103.675 1.00 37.22  ? 1147 TYR A CZ    1 
ATOM   6640  O  OH    . TYR A 1 1129 ? 144.634 100.273 105.010 1.00 37.22  ? 1147 TYR A OH    1 
ATOM   6641  N  N     . ARG A 1 1130 ? 141.258 99.910  97.186  1.00 35.46  ? 1148 ARG A N     1 
ATOM   6642  C  CA    . ARG A 1 1130 ? 140.789 99.824  95.810  1.00 35.46  ? 1148 ARG A CA    1 
ATOM   6643  C  C     . ARG A 1 1130 ? 140.434 101.200 95.275  1.00 35.46  ? 1148 ARG A C     1 
ATOM   6644  O  O     . ARG A 1 1130 ? 140.763 101.533 94.134  1.00 35.46  ? 1148 ARG A O     1 
ATOM   6645  C  CB    . ARG A 1 1130 ? 139.584 98.894  95.716  1.00 35.46  ? 1148 ARG A CB    1 
ATOM   6646  C  CG    . ARG A 1 1130 ? 139.905 97.437  95.932  1.00 35.46  ? 1148 ARG A CG    1 
ATOM   6647  C  CD    . ARG A 1 1130 ? 138.865 96.573  95.252  1.00 35.46  ? 1148 ARG A CD    1 
ATOM   6648  N  NE    . ARG A 1 1130 ? 137.521 96.848  95.744  1.00 35.46  ? 1148 ARG A NE    1 
ATOM   6649  C  CZ    . ARG A 1 1130 ? 136.410 96.435  95.151  1.00 35.46  ? 1148 ARG A CZ    1 
ATOM   6650  N  NH1   . ARG A 1 1130 ? 136.446 95.753  94.019  1.00 35.46  ? 1148 ARG A NH1   1 
ATOM   6651  N  NH2   . ARG A 1 1130 ? 135.235 96.716  95.706  1.00 35.46  ? 1148 ARG A NH2   1 
ATOM   6652  N  N     . ALA A 1 1131 ? 139.766 102.019 96.091  1.00 31.44  ? 1149 ALA A N     1 
ATOM   6653  C  CA    . ALA A 1 1131 ? 139.438 103.375 95.668  1.00 31.44  ? 1149 ALA A CA    1 
ATOM   6654  C  C     . ALA A 1 1131 ? 140.684 104.233 95.528  1.00 31.44  ? 1149 ALA A C     1 
ATOM   6655  O  O     . ALA A 1 1131 ? 140.734 105.108 94.660  1.00 31.44  ? 1149 ALA A O     1 
ATOM   6656  C  CB    . ALA A 1 1131 ? 138.466 104.019 96.650  1.00 31.44  ? 1149 ALA A CB    1 
ATOM   6657  N  N     . ALA A 1 1132 ? 141.695 104.009 96.369  1.00 31.92  ? 1150 ALA A N     1 
ATOM   6658  C  CA    . ALA A 1 1132 ? 142.954 104.726 96.201  1.00 31.92  ? 1150 ALA A CA    1 
ATOM   6659  C  C     . ALA A 1 1132 ? 143.615 104.364 94.877  1.00 31.92  ? 1150 ALA A C     1 
ATOM   6660  O  O     . ALA A 1 1132 ? 144.105 105.242 94.155  1.00 31.92  ? 1150 ALA A O     1 
ATOM   6661  C  CB    . ALA A 1 1132 ? 143.885 104.428 97.375  1.00 31.92  ? 1150 ALA A CB    1 
ATOM   6662  N  N     . LEU A 1 1133 ? 143.616 103.075 94.529  1.00 34.41  ? 1151 LEU A N     1 
ATOM   6663  C  CA    . LEU A 1 1133 ? 144.152 102.665 93.236  1.00 34.41  ? 1151 LEU A CA    1 
ATOM   6664  C  C     . LEU A 1 1133 ? 143.326 103.244 92.095  1.00 34.41  ? 1151 LEU A C     1 
ATOM   6665  O  O     . LEU A 1 1133 ? 143.873 103.631 91.056  1.00 34.41  ? 1151 LEU A O     1 
ATOM   6666  C  CB    . LEU A 1 1133 ? 144.203 101.142 93.140  1.00 34.41  ? 1151 LEU A CB    1 
ATOM   6667  C  CG    . LEU A 1 1133 ? 144.921 100.601 91.904  1.00 34.41  ? 1151 LEU A CG    1 
ATOM   6668  C  CD1   . LEU A 1 1133 ? 146.306 101.215 91.792  1.00 34.41  ? 1151 LEU A CD1   1 
ATOM   6669  C  CD2   . LEU A 1 1133 ? 145.006 99.087  91.950  1.00 34.41  ? 1151 LEU A CD2   1 
ATOM   6670  N  N     . ALA A 1 1134 ? 142.004 103.298 92.267  1.00 29.79  ? 1152 ALA A N     1 
ATOM   6671  C  CA    . ALA A 1 1134 ? 141.141 103.888 91.251  1.00 29.79  ? 1152 ALA A CA    1 
ATOM   6672  C  C     . ALA A 1 1134 ? 141.446 105.367 91.062  1.00 29.79  ? 1152 ALA A C     1 
ATOM   6673  O  O     . ALA A 1 1134 ? 141.446 105.866 89.935  1.00 29.79  ? 1152 ALA A O     1 
ATOM   6674  C  CB    . ALA A 1 1134 ? 139.674 103.686 91.626  1.00 29.79  ? 1152 ALA A CB    1 
ATOM   6675  N  N     . LEU A 1 1135 ? 141.783 106.064 92.134  1.00 28.51  ? 1153 LEU A N     1 
ATOM   6676  C  CA    . LEU A 1 1135 ? 142.104 107.488 92.043  1.00 28.51  ? 1153 LEU A CA    1 
ATOM   6677  C  C     . LEU A 1 1135 ? 143.455 107.694 91.418  1.00 28.51  ? 1153 LEU A C     1 
ATOM   6678  O  O     . LEU A 1 1135 ? 143.688 108.705 90.769  1.00 28.51  ? 1153 LEU A O     1 
ATOM   6679  C  CB    . LEU A 1 1135 ? 142.048 108.159 93.417  1.00 28.51  ? 1153 LEU A CB    1 
ATOM   6680  C  CG    . LEU A 1 1135 ? 140.721 108.753 93.875  1.00 28.51  ? 1153 LEU A CG    1 
ATOM   6681  C  CD1   . LEU A 1 1135 ? 140.615 108.716 95.389  1.00 28.51  ? 1153 LEU A CD1   1 
ATOM   6682  C  CD2   . LEU A 1 1135 ? 140.589 110.173 93.352  1.00 28.51  ? 1153 LEU A CD2   1 
ATOM   6683  N  N     . GLN A 1 1136 ? 144.372 106.771 91.645  1.00 29.59  ? 1154 GLN A N     1 
ATOM   6684  C  CA    . GLN A 1 1136 ? 145.664 106.844 90.970  1.00 29.59  ? 1154 GLN A CA    1 
ATOM   6685  C  C     . GLN A 1 1136 ? 145.519 106.585 89.474  1.00 29.59  ? 1154 GLN A C     1 
ATOM   6686  O  O     . GLN A 1 1136 ? 146.108 107.295 88.648  1.00 29.59  ? 1154 GLN A O     1 
ATOM   6687  C  CB    . GLN A 1 1136 ? 146.639 105.850 91.600  1.00 29.59  ? 1154 GLN A CB    1 
ATOM   6688  C  CG    . GLN A 1 1136 ? 146.922 106.097 93.075  1.00 29.59  ? 1154 GLN A CG    1 
ATOM   6689  C  CD    . GLN A 1 1136 ? 147.844 107.276 93.311  1.00 29.59  ? 1154 GLN A CD    1 
ATOM   6690  O  OE1   . GLN A 1 1136 ? 148.217 107.983 92.379  1.00 29.59  ? 1154 GLN A OE1   1 
ATOM   6691  N  NE2   . GLN A 1 1136 ? 148.223 107.487 94.562  1.00 29.59  ? 1154 GLN A NE2   1 
ATOM   6692  N  N     . ILE A 1 1137 ? 144.720 105.582 89.107  1.00 28.70  ? 1155 ILE A N     1 
ATOM   6693  C  CA    . ILE A 1 1137 ? 144.482 105.281 87.698  1.00 28.70  ? 1155 ILE A CA    1 
ATOM   6694  C  C     . ILE A 1 1137 ? 143.740 106.425 87.019  1.00 28.70  ? 1155 ILE A C     1 
ATOM   6695  O  O     . ILE A 1 1137 ? 144.021 106.763 85.865  1.00 28.70  ? 1155 ILE A O     1 
ATOM   6696  C  CB    . ILE A 1 1137 ? 143.725 103.948 87.563  1.00 28.70  ? 1155 ILE A CB    1 
ATOM   6697  C  CG1   . ILE A 1 1137 ? 144.595 102.805 88.074  1.00 28.70  ? 1155 ILE A CG1   1 
ATOM   6698  C  CG2   . ILE A 1 1137 ? 143.327 103.696 86.120  1.00 28.70  ? 1155 ILE A CG2   1 
ATOM   6699  C  CD1   . ILE A 1 1137 ? 143.907 101.478 88.056  1.00 28.70  ? 1155 ILE A CD1   1 
ATOM   6700  N  N     . THR A 1 1138 ? 142.770 107.028 87.713  1.00 28.27  ? 1156 THR A N     1 
ATOM   6701  C  CA    . THR A 1 1138 ? 142.040 108.157 87.145  1.00 28.27  ? 1156 THR A CA    1 
ATOM   6702  C  C     . THR A 1 1138 ? 142.960 109.343 86.902  1.00 28.27  ? 1156 THR A C     1 
ATOM   6703  O  O     . THR A 1 1138 ? 142.877 109.992 85.854  1.00 28.27  ? 1156 THR A O     1 
ATOM   6704  C  CB    . THR A 1 1138 ? 140.892 108.562 88.064  1.00 28.27  ? 1156 THR A CB    1 
ATOM   6705  O  OG1   . THR A 1 1138 ? 139.861 107.568 88.013  1.00 28.27  ? 1156 THR A OG1   1 
ATOM   6706  C  CG2   . THR A 1 1138 ? 140.320 109.901 87.638  1.00 28.27  ? 1156 THR A CG2   1 
ATOM   6707  N  N     . ASN A 1 1139 ? 143.846 109.643 87.855  1.00 28.03  ? 1157 ASN A N     1 
ATOM   6708  C  CA    . ASN A 1 1139 ? 144.817 110.709 87.639  1.00 28.03  ? 1157 ASN A CA    1 
ATOM   6709  C  C     . ASN A 1 1139 ? 145.720 110.393 86.456  1.00 28.03  ? 1157 ASN A C     1 
ATOM   6710  O  O     . ASN A 1 1139 ? 145.968 111.259 85.609  1.00 28.03  ? 1157 ASN A O     1 
ATOM   6711  C  CB    . ASN A 1 1139 ? 145.651 110.934 88.900  1.00 28.03  ? 1157 ASN A CB    1 
ATOM   6712  C  CG    . ASN A 1 1139 ? 146.552 112.150 88.790  1.00 28.03  ? 1157 ASN A CG    1 
ATOM   6713  O  OD1   . ASN A 1 1139 ? 146.351 113.009 87.935  1.00 28.03  ? 1157 ASN A OD1   1 
ATOM   6714  N  ND2   . ASN A 1 1139 ? 147.549 112.228 89.662  1.00 28.03  ? 1157 ASN A ND2   1 
ATOM   6715  N  N     . LEU A 1 1140 ? 146.206 109.152 86.370  1.00 28.37  ? 1158 LEU A N     1 
ATOM   6716  C  CA    . LEU A 1 1140 ? 147.059 108.765 85.250  1.00 28.37  ? 1158 LEU A CA    1 
ATOM   6717  C  C     . LEU A 1 1140 ? 146.343 108.963 83.920  1.00 28.37  ? 1158 LEU A C     1 
ATOM   6718  O  O     . LEU A 1 1140 ? 146.873 109.602 83.002  1.00 28.37  ? 1158 LEU A O     1 
ATOM   6719  C  CB    . LEU A 1 1140 ? 147.500 107.309 85.411  1.00 28.37  ? 1158 LEU A CB    1 
ATOM   6720  C  CG    . LEU A 1 1140 ? 148.303 106.668 84.278  1.00 28.37  ? 1158 LEU A CG    1 
ATOM   6721  C  CD1   . LEU A 1 1140 ? 149.677 107.299 84.164  1.00 28.37  ? 1158 LEU A CD1   1 
ATOM   6722  C  CD2   . LEU A 1 1140 ? 148.412 105.167 84.481  1.00 28.37  ? 1158 LEU A CD2   1 
ATOM   6723  N  N     . LEU A 1 1141 ? 145.125 108.427 83.805  1.00 28.97  ? 1159 LEU A N     1 
ATOM   6724  C  CA    . LEU A 1 1141 ? 144.381 108.509 82.553  1.00 28.97  ? 1159 LEU A CA    1 
ATOM   6725  C  C     . LEU A 1 1141 ? 144.034 109.948 82.206  1.00 28.97  ? 1159 LEU A C     1 
ATOM   6726  O  O     . LEU A 1 1141 ? 144.075 110.336 81.036  1.00 28.97  ? 1159 LEU A O     1 
ATOM   6727  C  CB    . LEU A 1 1141 ? 143.114 107.662 82.640  1.00 28.97  ? 1159 LEU A CB    1 
ATOM   6728  C  CG    . LEU A 1 1141 ? 143.329 106.159 82.801  1.00 28.97  ? 1159 LEU A CG    1 
ATOM   6729  C  CD1   . LEU A 1 1141 ? 141.997 105.424 82.844  1.00 28.97  ? 1159 LEU A CD1   1 
ATOM   6730  C  CD2   . LEU A 1 1141 ? 144.211 105.631 81.684  1.00 28.97  ? 1159 LEU A CD2   1 
ATOM   6731  N  N     . THR A 1 1142 ? 143.669 110.752 83.207  1.00 28.04  ? 1160 THR A N     1 
ATOM   6732  C  CA    . THR A 1 1142 ? 143.334 112.148 82.954  1.00 28.04  ? 1160 THR A CA    1 
ATOM   6733  C  C     . THR A 1 1142 ? 144.543 112.929 82.463  1.00 28.04  ? 1160 THR A C     1 
ATOM   6734  O  O     . THR A 1 1142 ? 144.434 113.714 81.514  1.00 28.04  ? 1160 THR A O     1 
ATOM   6735  C  CB    . THR A 1 1142 ? 142.766 112.780 84.221  1.00 28.04  ? 1160 THR A CB    1 
ATOM   6736  O  OG1   . THR A 1 1142 ? 141.583 112.076 84.612  1.00 28.04  ? 1160 THR A OG1   1 
ATOM   6737  C  CG2   . THR A 1 1142 ? 142.423 114.230 83.977  1.00 28.04  ? 1160 THR A CG2   1 
ATOM   6738  N  N     . ARG A 1 1143 ? 145.704 112.735 83.095  1.00 28.32  ? 1161 ARG A N     1 
ATOM   6739  C  CA    . ARG A 1 1143 ? 146.907 113.408 82.616  1.00 28.32  ? 1161 ARG A CA    1 
ATOM   6740  C  C     . ARG A 1 1143 ? 147.267 112.951 81.208  1.00 28.32  ? 1161 ARG A C     1 
ATOM   6741  O  O     . ARG A 1 1143 ? 147.668 113.770 80.370  1.00 28.32  ? 1161 ARG A O     1 
ATOM   6742  C  CB    . ARG A 1 1143 ? 148.079 113.160 83.568  1.00 28.32  ? 1161 ARG A CB    1 
ATOM   6743  C  CG    . ARG A 1 1143 ? 147.840 113.550 85.019  1.00 28.32  ? 1161 ARG A CG    1 
ATOM   6744  C  CD    . ARG A 1 1143 ? 147.397 114.987 85.154  1.00 28.32  ? 1161 ARG A CD    1 
ATOM   6745  N  NE    . ARG A 1 1143 ? 148.430 115.845 85.723  1.00 28.32  ? 1161 ARG A NE    1 
ATOM   6746  C  CZ    . ARG A 1 1143 ? 148.558 116.109 87.016  1.00 28.32  ? 1161 ARG A CZ    1 
ATOM   6747  N  NH1   . ARG A 1 1143 ? 147.753 115.569 87.915  1.00 28.32  ? 1161 ARG A NH1   1 
ATOM   6748  N  NH2   . ARG A 1 1143 ? 149.514 116.941 87.416  1.00 28.32  ? 1161 ARG A NH2   1 
ATOM   6749  N  N     . CYS A 1 1144 ? 147.120 111.653 80.928  1.00 36.14  ? 1162 CYS A N     1 
ATOM   6750  C  CA    . CYS A 1 1144 ? 147.421 111.147 79.594  1.00 36.14  ? 1162 CYS A CA    1 
ATOM   6751  C  C     . CYS A 1 1144 ? 146.466 111.718 78.555  1.00 36.14  ? 1162 CYS A C     1 
ATOM   6752  O  O     . CYS A 1 1144 ? 146.879 112.031 77.437  1.00 36.14  ? 1162 CYS A O     1 
ATOM   6753  C  CB    . CYS A 1 1144 ? 147.372 109.621 79.587  1.00 36.14  ? 1162 CYS A CB    1 
ATOM   6754  S  SG    . CYS A 1 1144 ? 148.693 108.829 80.519  1.00 36.14  ? 1162 CYS A SG    1 
ATOM   6755  N  N     . MET A 1 1145 ? 145.184 111.848 78.901  1.00 34.83  ? 1163 MET A N     1 
ATOM   6756  C  CA    . MET A 1 1145 ? 144.210 112.453 77.997  1.00 34.83  ? 1163 MET A CA    1 
ATOM   6757  C  C     . MET A 1 1145 ? 144.520 113.922 77.751  1.00 34.83  ? 1163 MET A C     1 
ATOM   6758  O  O     . MET A 1 1145 ? 144.424 114.405 76.617  1.00 34.83  ? 1163 MET A O     1 
ATOM   6759  C  CB    . MET A 1 1145 ? 142.805 112.296 78.573  1.00 34.83  ? 1163 MET A CB    1 
ATOM   6760  C  CG    . MET A 1 1145 ? 141.738 113.115 77.873  1.00 34.83  ? 1163 MET A CG    1 
ATOM   6761  S  SD    . MET A 1 1145 ? 141.236 112.421 76.290  1.00 34.83  ? 1163 MET A SD    1 
ATOM   6762  C  CE    . MET A 1 1145 ? 139.737 113.351 75.984  1.00 34.83  ? 1163 MET A CE    1 
ATOM   6763  N  N     . PHE A 1 1146 ? 144.888 114.647 78.784  1.00 30.47  ? 1164 PHE A N     1 
ATOM   6764  C  CA    . PHE A 1 1146 ? 145.245 116.036 78.619  1.00 30.47  ? 1164 PHE A CA    1 
ATOM   6765  C  C     . PHE A 1 1146 ? 146.460 116.194 77.734  1.00 30.47  ? 1164 PHE A C     1 
ATOM   6766  O  O     . PHE A 1 1146 ? 146.517 117.121 76.938  1.00 30.47  ? 1164 PHE A O     1 
ATOM   6767  C  CB    . PHE A 1 1146 ? 145.539 116.662 79.973  1.00 30.47  ? 1164 PHE A CB    1 
ATOM   6768  C  CG    . PHE A 1 1146 ? 144.598 117.761 80.356  1.00 30.47  ? 1164 PHE A CG    1 
ATOM   6769  C  CD1   . PHE A 1 1146 ? 143.373 117.472 80.926  1.00 30.47  ? 1164 PHE A CD1   1 
ATOM   6770  C  CD2   . PHE A 1 1146 ? 144.950 119.085 80.161  1.00 30.47  ? 1164 PHE A CD2   1 
ATOM   6771  C  CE1   . PHE A 1 1146 ? 142.507 118.484 81.282  1.00 30.47  ? 1164 PHE A CE1   1 
ATOM   6772  C  CE2   . PHE A 1 1146 ? 144.091 120.101 80.516  1.00 30.47  ? 1164 PHE A CE2   1 
ATOM   6773  C  CZ    . PHE A 1 1146 ? 142.869 119.801 81.080  1.00 30.47  ? 1164 PHE A CZ    1 
ATOM   6774  N  N     . ALA A 1 1147 ? 147.447 115.307 77.870  1.00 38.07  ? 1165 ALA A N     1 
ATOM   6775  C  CA    . ALA A 1 1147 ? 148.612 115.372 76.998  1.00 38.07  ? 1165 ALA A CA    1 
ATOM   6776  C  C     . ALA A 1 1147 ? 148.300 114.908 75.580  1.00 38.07  ? 1165 ALA A C     1 
ATOM   6777  O  O     . ALA A 1 1147 ? 148.885 115.425 74.622  1.00 38.07  ? 1165 ALA A O     1 
ATOM   6778  C  CB    . ALA A 1 1147 ? 149.752 114.537 77.580  1.00 38.07  ? 1165 ALA A CB    1 
ATOM   6779  N  N     . TYR A 1 1148 ? 147.389 113.945 75.424  1.00 37.54  ? 1166 TYR A N     1 
ATOM   6780  C  CA    . TYR A 1 1148 ? 147.089 113.408 74.102  1.00 37.54  ? 1166 TYR A CA    1 
ATOM   6781  C  C     . TYR A 1 1148 ? 146.266 114.384 73.276  1.00 37.54  ? 1166 TYR A C     1 
ATOM   6782  O  O     . TYR A 1 1148 ? 146.532 114.568 72.083  1.00 37.54  ? 1166 TYR A O     1 
ATOM   6783  C  CB    . TYR A 1 1148 ? 146.359 112.074 74.231  1.00 37.54  ? 1166 TYR A CB    1 
ATOM   6784  C  CG    . TYR A 1 1148 ? 145.833 111.554 72.916  1.00 37.54  ? 1166 TYR A CG    1 
ATOM   6785  C  CD1   . TYR A 1 1148 ? 146.686 110.985 71.981  1.00 37.54  ? 1166 TYR A CD1   1 
ATOM   6786  C  CD2   . TYR A 1 1148 ? 144.483 111.630 72.608  1.00 37.54  ? 1166 TYR A CD2   1 
ATOM   6787  C  CE1   . TYR A 1 1148 ? 146.209 110.510 70.776  1.00 37.54  ? 1166 TYR A CE1   1 
ATOM   6788  C  CE2   . TYR A 1 1148 ? 143.998 111.157 71.407  1.00 37.54  ? 1166 TYR A CE2   1 
ATOM   6789  C  CZ    . TYR A 1 1148 ? 144.864 110.598 70.496  1.00 37.54  ? 1166 TYR A CZ    1 
ATOM   6790  O  OH    . TYR A 1 1148 ? 144.381 110.127 69.299  1.00 37.54  ? 1166 TYR A OH    1 
ATOM   6791  N  N     . LYS A 1 1149 ? 145.257 115.013 73.884  1.00 36.32  ? 1167 LYS A N     1 
ATOM   6792  C  CA    . LYS A 1 1149 ? 144.464 115.995 73.153  1.00 36.32  ? 1167 LYS A CA    1 
ATOM   6793  C  C     . LYS A 1 1149 ? 145.293 117.202 72.750  1.00 36.32  ? 1167 LYS A C     1 
ATOM   6794  O  O     . LYS A 1 1149 ? 144.862 117.982 71.894  1.00 36.32  ? 1167 LYS A O     1 
ATOM   6795  C  CB    . LYS A 1 1149 ? 143.268 116.444 73.991  1.00 36.32  ? 1167 LYS A CB    1 
ATOM   6796  C  CG    . LYS A 1 1149 ? 142.289 115.336 74.314  1.00 36.32  ? 1167 LYS A CG    1 
ATOM   6797  C  CD    . LYS A 1 1149 ? 141.592 114.829 73.065  1.00 36.32  ? 1167 LYS A CD    1 
ATOM   6798  C  CE    . LYS A 1 1149 ? 140.754 115.920 72.421  1.00 36.32  ? 1167 LYS A CE    1 
ATOM   6799  N  NZ    . LYS A 1 1149 ? 139.965 115.415 71.265  1.00 36.32  ? 1167 LYS A NZ    1 
ATOM   6800  N  N     . LEU A 1 1150 ? 146.464 117.377 73.350  1.00 37.42  ? 1168 LEU A N     1 
ATOM   6801  C  CA    . LEU A 1 1150 ? 147.401 118.419 72.967  1.00 37.42  ? 1168 LEU A CA    1 
ATOM   6802  C  C     . LEU A 1 1150 ? 148.468 117.928 71.998  1.00 37.42  ? 1168 LEU A C     1 
ATOM   6803  O  O     . LEU A 1 1150 ? 149.277 118.735 71.532  1.00 37.42  ? 1168 LEU A O     1 
ATOM   6804  C  CB    . LEU A 1 1150 ? 148.066 119.001 74.214  1.00 37.42  ? 1168 LEU A CB    1 
ATOM   6805  C  CG    . LEU A 1 1150 ? 147.148 119.718 75.200  1.00 37.42  ? 1168 LEU A CG    1 
ATOM   6806  C  CD1   . LEU A 1 1150 ? 147.948 120.249 76.377  1.00 37.42  ? 1168 LEU A CD1   1 
ATOM   6807  C  CD2   . LEU A 1 1150 ? 146.402 120.836 74.501  1.00 37.42  ? 1168 LEU A CD2   1 
ATOM   6808  N  N     . GLY A 1 1151 ? 148.489 116.635 71.684  1.00 41.80  ? 1169 GLY A N     1 
ATOM   6809  C  CA    . GLY A 1 1151 ? 149.488 116.086 70.791  1.00 41.80  ? 1169 GLY A CA    1 
ATOM   6810  C  C     . GLY A 1 1151 ? 150.811 115.738 71.433  1.00 41.80  ? 1169 GLY A C     1 
ATOM   6811  O  O     . GLY A 1 1151 ? 151.781 115.482 70.711  1.00 41.80  ? 1169 GLY A O     1 
ATOM   6812  N  N     . LEU A 1 1152 ? 150.887 115.723 72.766  1.00 43.32  ? 1170 LEU A N     1 
ATOM   6813  C  CA    . LEU A 1 1152 ? 152.134 115.362 73.433  1.00 43.32  ? 1170 LEU A CA    1 
ATOM   6814  C  C     . LEU A 1 1152 ? 152.412 113.869 73.315  1.00 43.32  ? 1170 LEU A C     1 
ATOM   6815  O  O     . LEU A 1 1152 ? 153.557 113.463 73.085  1.00 43.32  ? 1170 LEU A O     1 
ATOM   6816  C  CB    . LEU A 1 1152 ? 152.084 115.785 74.899  1.00 43.32  ? 1170 LEU A CB    1 
ATOM   6817  C  CG    . LEU A 1 1152 ? 151.971 117.290 75.131  1.00 43.32  ? 1170 LEU A CG    1 
ATOM   6818  C  CD1   . LEU A 1 1152 ? 151.817 117.595 76.609  1.00 43.32  ? 1170 LEU A CD1   1 
ATOM   6819  C  CD2   . LEU A 1 1152 ? 153.186 117.997 74.559  1.00 43.32  ? 1170 LEU A CD2   1 
ATOM   6820  N  N     . ASN A 1 1153 ? 151.379 113.041 73.480  1.00 44.34  ? 1171 ASN A N     1 
ATOM   6821  C  CA    . ASN A 1 1153 ? 151.474 111.594 73.273  1.00 44.34  ? 1171 ASN A CA    1 
ATOM   6822  C  C     . ASN A 1 1153 ? 152.509 110.957 74.200  1.00 44.34  ? 1171 ASN A C     1 
ATOM   6823  O  O     . ASN A 1 1153 ? 153.197 110.004 73.827  1.00 44.34  ? 1171 ASN A O     1 
ATOM   6824  C  CB    . ASN A 1 1153 ? 151.783 111.273 71.808  1.00 44.34  ? 1171 ASN A CB    1 
ATOM   6825  C  CG    . ASN A 1 1153 ? 151.246 109.923 71.379  1.00 44.34  ? 1171 ASN A CG    1 
ATOM   6826  O  OD1   . ASN A 1 1153 ? 150.334 109.380 71.998  1.00 44.34  ? 1171 ASN A OD1   1 
ATOM   6827  N  ND2   . ASN A 1 1153 ? 151.806 109.380 70.305  1.00 44.34  ? 1171 ASN A ND2   1 
ATOM   6828  N  N     . ASP A 1 1154 ? 152.622 111.486 75.417  1.00 44.40  ? 1172 ASP A N     1 
ATOM   6829  C  CA    . ASP A 1 1154 ? 153.543 110.961 76.418  1.00 44.40  ? 1172 ASP A CA    1 
ATOM   6830  C  C     . ASP A 1 1154 ? 153.195 111.580 77.763  1.00 44.40  ? 1172 ASP A C     1 
ATOM   6831  O  O     . ASP A 1 1154 ? 152.505 112.601 77.830  1.00 44.40  ? 1172 ASP A O     1 
ATOM   6832  C  CB    . ASP A 1 1154 ? 155.003 111.251 76.051  1.00 44.40  ? 1172 ASP A CB    1 
ATOM   6833  C  CG    . ASP A 1 1154 ? 155.939 110.140 76.473  1.00 44.40  ? 1172 ASP A CG    1 
ATOM   6834  O  OD1   . ASP A 1 1154 ? 155.470 109.184 77.124  1.00 44.40  ? 1172 ASP A OD1   1 
ATOM   6835  O  OD2   . ASP A 1 1154 ? 157.142 110.220 76.151  1.00 44.40  ? 1172 ASP A OD2   1 
ATOM   6836  N  N     . LEU A 1 1155 ? 153.683 110.952 78.838  1.00 35.16  ? 1173 LEU A N     1 
ATOM   6837  C  CA    . LEU A 1 1155 ? 153.436 111.474 80.181  1.00 35.16  ? 1173 LEU A CA    1 
ATOM   6838  C  C     . LEU A 1 1155 ? 154.594 111.142 81.115  1.00 35.16  ? 1173 LEU A C     1 
ATOM   6839  O  O     . LEU A 1 1155 ? 155.013 109.976 81.170  1.00 35.16  ? 1173 LEU A O     1 
ATOM   6840  C  CB    . LEU A 1 1155 ? 152.134 110.925 80.766  1.00 35.16  ? 1173 LEU A CB    1 
ATOM   6841  C  CG    . LEU A 1 1155 ? 151.728 111.529 82.111  1.00 35.16  ? 1173 LEU A CG    1 
ATOM   6842  C  CD1   . LEU A 1 1155 ? 151.297 112.977 81.942  1.00 35.16  ? 1173 LEU A CD1   1 
ATOM   6843  C  CD2   . LEU A 1 1155 ? 150.639 110.708 82.773  1.00 35.16  ? 1173 LEU A CD2   1 
ATOM   6844  N  N     . PRO A 1 1156 ? 155.122 112.123 81.843  1.00 36.08  ? 1174 PRO A N     1 
ATOM   6845  C  CA    . PRO A 1 1156 ? 156.208 111.845 82.788  1.00 36.08  ? 1174 PRO A CA    1 
ATOM   6846  C  C     . PRO A 1 1156 ? 155.734 111.026 83.978  1.00 36.08  ? 1174 PRO A C     1 
ATOM   6847  O  O     . PRO A 1 1156 ? 154.553 110.998 84.327  1.00 36.08  ? 1174 PRO A O     1 
ATOM   6848  C  CB    . PRO A 1 1156 ? 156.666 113.241 83.227  1.00 36.08  ? 1174 PRO A CB    1 
ATOM   6849  C  CG    . PRO A 1 1156 ? 156.165 114.162 82.170  1.00 36.08  ? 1174 PRO A CG    1 
ATOM   6850  C  CD    . PRO A 1 1156 ? 154.881 113.566 81.697  1.00 36.08  ? 1174 PRO A CD    1 
ATOM   6851  N  N     . GLN A 1 1157 ? 156.695 110.341 84.603  1.00 35.74  ? 1175 GLN A N     1 
ATOM   6852  C  CA    . GLN A 1 1157 ? 156.406 109.554 85.796  1.00 35.74  ? 1175 GLN A CA    1 
ATOM   6853  C  C     . GLN A 1 1157 ? 156.116 110.434 87.006  1.00 35.74  ? 1175 GLN A C     1 
ATOM   6854  O  O     . GLN A 1 1157 ? 155.481 109.969 87.959  1.00 35.74  ? 1175 GLN A O     1 
ATOM   6855  C  CB    . GLN A 1 1157 ? 157.580 108.621 86.095  1.00 35.74  ? 1175 GLN A CB    1 
ATOM   6856  C  CG    . GLN A 1 1157 ? 157.300 107.540 87.125  1.00 35.74  ? 1175 GLN A CG    1 
ATOM   6857  C  CD    . GLN A 1 1157 ? 156.466 106.403 86.571  1.00 35.74  ? 1175 GLN A CD    1 
ATOM   6858  O  OE1   . GLN A 1 1157 ? 156.295 106.276 85.360  1.00 35.74  ? 1175 GLN A OE1   1 
ATOM   6859  N  NE2   . GLN A 1 1157 ? 155.942 105.568 87.459  1.00 35.74  ? 1175 GLN A NE2   1 
ATOM   6860  N  N     . SER A 1 1158 ? 156.565 111.690 86.983  1.00 37.75  ? 1176 SER A N     1 
ATOM   6861  C  CA    . SER A 1 1158 ? 156.359 112.584 88.118  1.00 37.75  ? 1176 SER A CA    1 
ATOM   6862  C  C     . SER A 1 1158 ? 154.877 112.793 88.399  1.00 37.75  ? 1176 SER A C     1 
ATOM   6863  O  O     . SER A 1 1158 ? 154.416 112.618 89.533  1.00 37.75  ? 1176 SER A O     1 
ATOM   6864  C  CB    . SER A 1 1158 ? 157.049 113.922 87.851  1.00 37.75  ? 1176 SER A CB    1 
ATOM   6865  O  OG    . SER A 1 1158 ? 156.651 114.900 88.794  1.00 37.75  ? 1176 SER A OG    1 
ATOM   6866  N  N     . VAL A 1 1159 ? 154.110 113.154 87.370  1.00 28.22  ? 1177 VAL A N     1 
ATOM   6867  C  CA    . VAL A 1 1159 ? 152.706 113.515 87.525  1.00 28.22  ? 1177 VAL A CA    1 
ATOM   6868  C  C     . VAL A 1 1159 ? 151.776 112.356 87.190  1.00 28.22  ? 1177 VAL A C     1 
ATOM   6869  O  O     . VAL A 1 1159 ? 150.557 112.532 87.167  1.00 28.22  ? 1177 VAL A O     1 
ATOM   6870  C  CB    . VAL A 1 1159 ? 152.362 114.745 86.674  1.00 28.22  ? 1177 VAL A CB    1 
ATOM   6871  C  CG1   . VAL A 1 1159 ? 153.160 115.948 87.141  1.00 28.22  ? 1177 VAL A CG1   1 
ATOM   6872  C  CG2   . VAL A 1 1159 ? 152.636 114.457 85.216  1.00 28.22  ? 1177 VAL A CG2   1 
ATOM   6873  N  N     . ALA A 1 1160 ? 152.325 111.173 86.929  1.00 29.31  ? 1178 ALA A N     1 
ATOM   6874  C  CA    . ALA A 1 1160 ? 151.511 110.041 86.512  1.00 29.31  ? 1178 ALA A CA    1 
ATOM   6875  C  C     . ALA A 1 1160 ? 150.601 109.517 87.613  1.00 29.31  ? 1178 ALA A C     1 
ATOM   6876  O  O     . ALA A 1 1160 ? 149.681 108.749 87.312  1.00 29.31  ? 1178 ALA A O     1 
ATOM   6877  C  CB    . ALA A 1 1160 ? 152.409 108.912 86.009  1.00 29.31  ? 1178 ALA A CB    1 
ATOM   6878  N  N     . PHE A 1 1161 ? 150.827 109.900 88.868  1.00 29.36  ? 1179 PHE A N     1 
ATOM   6879  C  CA    . PHE A 1 1161 ? 150.072 109.339 89.978  1.00 29.36  ? 1179 PHE A CA    1 
ATOM   6880  C  C     . PHE A 1 1161 ? 149.947 110.375 91.085  1.00 29.36  ? 1179 PHE A C     1 
ATOM   6881  O  O     . PHE A 1 1161 ? 150.722 111.333 91.158  1.00 29.36  ? 1179 PHE A O     1 
ATOM   6882  C  CB    . PHE A 1 1161 ? 150.734 108.066 90.521  1.00 29.36  ? 1179 PHE A CB    1 
ATOM   6883  C  CG    . PHE A 1 1161 ? 150.680 106.900 89.579  1.00 29.36  ? 1179 PHE A CG    1 
ATOM   6884  C  CD1   . PHE A 1 1161 ? 149.557 106.098 89.515  1.00 29.36  ? 1179 PHE A CD1   1 
ATOM   6885  C  CD2   . PHE A 1 1161 ? 151.759 106.597 88.770  1.00 29.36  ? 1179 PHE A CD2   1 
ATOM   6886  C  CE1   . PHE A 1 1161 ? 149.506 105.021 88.658  1.00 29.36  ? 1179 PHE A CE1   1 
ATOM   6887  C  CE2   . PHE A 1 1161 ? 151.713 105.522 87.909  1.00 29.36  ? 1179 PHE A CE2   1 
ATOM   6888  C  CZ    . PHE A 1 1161 ? 150.586 104.733 87.854  1.00 29.36  ? 1179 PHE A CZ    1 
ATOM   6889  N  N     . PHE A 1 1162 ? 148.958 110.169 91.950  1.00 27.19  ? 1180 PHE A N     1 
ATOM   6890  C  CA    . PHE A 1 1162 ? 148.758 111.054 93.088  1.00 27.19  ? 1180 PHE A CA    1 
ATOM   6891  C  C     . PHE A 1 1162 ? 149.898 110.903 94.084  1.00 27.19  ? 1180 PHE A C     1 
ATOM   6892  O  O     . PHE A 1 1162 ? 150.331 109.789 94.391  1.00 27.19  ? 1180 PHE A O     1 
ATOM   6893  C  CB    . PHE A 1 1162 ? 147.430 110.747 93.780  1.00 27.19  ? 1180 PHE A CB    1 
ATOM   6894  C  CG    . PHE A 1 1162 ? 146.245 111.416 93.153  1.00 27.19  ? 1180 PHE A CG    1 
ATOM   6895  C  CD1   . PHE A 1 1162 ? 146.261 112.773 92.884  1.00 27.19  ? 1180 PHE A CD1   1 
ATOM   6896  C  CD2   . PHE A 1 1162 ? 145.113 110.686 92.834  1.00 27.19  ? 1180 PHE A CD2   1 
ATOM   6897  C  CE1   . PHE A 1 1162 ? 145.171 113.388 92.309  1.00 27.19  ? 1180 PHE A CE1   1 
ATOM   6898  C  CE2   . PHE A 1 1162 ? 144.023 111.296 92.258  1.00 27.19  ? 1180 PHE A CE2   1 
ATOM   6899  C  CZ    . PHE A 1 1162 ? 144.051 112.649 91.996  1.00 27.19  ? 1180 PHE A CZ    1 
ATOM   6900  N  N     . SER A 1 1163 ? 150.382 112.037 94.594  1.00 28.02  ? 1181 SER A N     1 
ATOM   6901  C  CA    . SER A 1 1163 ? 151.425 112.001 95.614  1.00 28.02  ? 1181 SER A CA    1 
ATOM   6902  C  C     . SER A 1 1163 ? 150.934 111.289 96.868  1.00 28.02  ? 1181 SER A C     1 
ATOM   6903  O  O     . SER A 1 1163 ? 151.656 110.481 97.462  1.00 28.02  ? 1181 SER A O     1 
ATOM   6904  C  CB    . SER A 1 1163 ? 151.888 113.420 95.944  1.00 28.02  ? 1181 SER A CB    1 
ATOM   6905  O  OG    . SER A 1 1163 ? 152.379 114.079 94.791  1.00 28.02  ? 1181 SER A OG    1 
ATOM   6906  N  N     . ALA A 1 1164 ? 149.703 111.574 97.283  1.00 23.51  ? 1182 ALA A N     1 
ATOM   6907  C  CA    . ALA A 1 1164 ? 149.146 110.969 98.488  1.00 23.51  ? 1182 ALA A CA    1 
ATOM   6908  C  C     . ALA A 1 1164 ? 147.631 110.969 98.370  1.00 23.51  ? 1182 ALA A C     1 
ATOM   6909  O  O     . ALA A 1 1164 ? 147.024 112.029 98.197  1.00 23.51  ? 1182 ALA A O     1 
ATOM   6910  C  CB    . ALA A 1 1164 ? 149.600 111.716 99.737  1.00 23.51  ? 1182 ALA A CB    1 
ATOM   6911  N  N     . VAL A 1 1165 ? 147.029 109.789 98.457  1.00 21.34  ? 1183 VAL A N     1 
ATOM   6912  C  CA    . VAL A 1 1165 ? 145.576 109.667 98.474  1.00 21.34  ? 1183 VAL A CA    1 
ATOM   6913  C  C     . VAL A 1 1165 ? 145.119 109.588 99.924  1.00 21.34  ? 1183 VAL A C     1 
ATOM   6914  O  O     . VAL A 1 1165 ? 145.128 108.512 100.532 1.00 21.34  ? 1183 VAL A O     1 
ATOM   6915  C  CB    . VAL A 1 1165 ? 145.112 108.442 97.676  1.00 21.34  ? 1183 VAL A CB    1 
ATOM   6916  C  CG1   . VAL A 1 1165 ? 143.602 108.330 97.714  1.00 21.34  ? 1183 VAL A CG1   1 
ATOM   6917  C  CG2   . VAL A 1 1165 ? 145.597 108.539 96.246  1.00 21.34  ? 1183 VAL A CG2   1 
ATOM   6918  N  N     . ASP A 1 1166 ? 144.744 110.733 100.477 1.00 20.46  ? 1184 ASP A N     1 
ATOM   6919  C  CA    . ASP A 1 1166 ? 144.358 110.824 101.880 1.00 20.46  ? 1184 ASP A CA    1 
ATOM   6920  C  C     . ASP A 1 1166 ? 143.163 110.025 102.319 1.00 20.46  ? 1184 ASP A C     1 
ATOM   6921  O  O     . ASP A 1 1166 ? 142.034 110.456 102.150 1.00 20.46  ? 1184 ASP A O     1 
ATOM   6922  C  CB    . ASP A 1 1166 ? 144.091 112.294 102.199 1.00 20.46  ? 1184 ASP A CB    1 
ATOM   6923  C  CG    . ASP A 1 1166 ? 145.111 113.220 101.580 1.00 20.46  ? 1184 ASP A CG    1 
ATOM   6924  O  OD1   . ASP A 1 1166 ? 146.078 112.726 100.971 1.00 20.46  ? 1184 ASP A OD1   1 
ATOM   6925  O  OD2   . ASP A 1 1166 ? 144.946 114.449 101.700 1.00 20.46  ? 1184 ASP A OD2   1 
ATOM   6926  N  N     . ILE A 1 1167 ? 143.398 108.875 102.903 1.00 24.70  ? 1185 ILE A N     1 
ATOM   6927  C  CA    . ILE A 1 1167 ? 142.311 108.075 103.453 1.00 24.70  ? 1185 ILE A CA    1 
ATOM   6928  C  C     . ILE A 1 1167 ? 142.033 108.632 104.844 1.00 24.70  ? 1185 ILE A C     1 
ATOM   6929  O  O     . ILE A 1 1167 ? 142.890 108.590 105.727 1.00 24.70  ? 1185 ILE A O     1 
ATOM   6930  C  CB    . ILE A 1 1167 ? 142.656 106.588 103.489 1.00 24.70  ? 1185 ILE A CB    1 
ATOM   6931  C  CG1   . ILE A 1 1167 ? 143.050 106.105 102.096 1.00 24.70  ? 1185 ILE A CG1   1 
ATOM   6932  C  CG2   . ILE A 1 1167 ? 141.480 105.788 104.014 1.00 24.70  ? 1185 ILE A CG2   1 
ATOM   6933  C  CD1   . ILE A 1 1167 ? 143.191 104.614 101.994 1.00 24.70  ? 1185 ILE A CD1   1 
ATOM   6934  N  N     . ASP A 1 1168 ? 140.827 109.163 105.039 1.00 25.47  ? 1186 ASP A N     1 
ATOM   6935  C  CA    . ASP A 1 1168 ? 140.514 109.893 106.261 1.00 25.47  ? 1186 ASP A CA    1 
ATOM   6936  C  C     . ASP A 1 1168 ? 139.083 109.621 106.704 1.00 25.47  ? 1186 ASP A C     1 
ATOM   6937  O  O     . ASP A 1 1168 ? 138.421 108.728 106.167 1.00 25.47  ? 1186 ASP A O     1 
ATOM   6938  C  CB    . ASP A 1 1168 ? 140.734 111.390 106.040 1.00 25.47  ? 1186 ASP A CB    1 
ATOM   6939  C  CG    . ASP A 1 1168 ? 141.055 112.129 107.318 1.00 25.47  ? 1186 ASP A CG    1 
ATOM   6940  O  OD1   . ASP A 1 1168 ? 140.602 111.688 108.393 1.00 25.47  ? 1186 ASP A OD1   1 
ATOM   6941  O  OD2   . ASP A 1 1168 ? 141.762 113.154 107.250 1.00 25.47  ? 1186 ASP A OD2   1 
ATOM   6942  N  N     . ARG A 1 1169 ? 138.600 110.379 107.690 1.00 22.21  ? 1187 ARG A N     1 
ATOM   6943  C  CA    . ARG A 1 1169 ? 137.206 110.320 108.108 1.00 22.21  ? 1187 ARG A CA    1 
ATOM   6944  C  C     . ARG A 1 1169 ? 136.619 111.704 108.348 1.00 22.21  ? 1187 ARG A C     1 
ATOM   6945  O  O     . ARG A 1 1169 ? 135.497 111.808 108.852 1.00 22.21  ? 1187 ARG A O     1 
ATOM   6946  C  CB    . ARG A 1 1169 ? 137.041 109.467 109.370 1.00 22.21  ? 1187 ARG A CB    1 
ATOM   6947  C  CG    . ARG A 1 1169 ? 137.053 107.972 109.120 1.00 22.21  ? 1187 ARG A CG    1 
ATOM   6948  C  CD    . ARG A 1 1169 ? 136.119 107.256 110.081 1.00 22.21  ? 1187 ARG A CD    1 
ATOM   6949  N  NE    . ARG A 1 1169 ? 136.402 107.596 111.469 1.00 22.21  ? 1187 ARG A NE    1 
ATOM   6950  C  CZ    . ARG A 1 1169 ? 135.677 107.193 112.504 1.00 22.21  ? 1187 ARG A CZ    1 
ATOM   6951  N  NH1   . ARG A 1 1169 ? 134.605 106.436 112.344 1.00 22.21  ? 1187 ARG A NH1   1 
ATOM   6952  N  NH2   . ARG A 1 1169 ? 136.037 107.560 113.730 1.00 22.21  ? 1187 ARG A NH2   1 
ATOM   6953  N  N     . CYS A 1 1170 ? 137.348 112.764 108.012 1.00 21.58  ? 1188 CYS A N     1 
ATOM   6954  C  CA    . CYS A 1 1170 ? 136.822 114.123 108.108 1.00 21.58  ? 1188 CYS A CA    1 
ATOM   6955  C  C     . CYS A 1 1170 ? 137.653 115.004 107.192 1.00 21.58  ? 1188 CYS A C     1 
ATOM   6956  O  O     . CYS A 1 1170 ? 138.882 114.890 107.179 1.00 21.58  ? 1188 CYS A O     1 
ATOM   6957  C  CB    . CYS A 1 1170 ? 136.854 114.636 109.548 1.00 21.58  ? 1188 CYS A CB    1 
ATOM   6958  S  SG    . CYS A 1 1170 ? 138.491 115.006 110.209 1.00 21.58  ? 1188 CYS A SG    1 
ATOM   6959  N  N     . LEU A 1 1171 ? 136.990 115.858 106.418 1.00 19.65  ? 1189 LEU A N     1 
ATOM   6960  C  CA    . LEU A 1 1171 ? 137.688 116.693 105.452 1.00 19.65  ? 1189 LEU A CA    1 
ATOM   6961  C  C     . LEU A 1 1171 ? 138.717 117.576 106.142 1.00 19.65  ? 1189 LEU A C     1 
ATOM   6962  O  O     . LEU A 1 1171 ? 138.417 118.247 107.132 1.00 19.65  ? 1189 LEU A O     1 
ATOM   6963  C  CB    . LEU A 1 1171 ? 136.682 117.550 104.684 1.00 19.65  ? 1189 LEU A CB    1 
ATOM   6964  C  CG    . LEU A 1 1171 ? 135.620 116.757 103.925 1.00 19.65  ? 1189 LEU A CG    1 
ATOM   6965  C  CD1   . LEU A 1 1171 ? 134.670 117.683 103.189 1.00 19.65  ? 1189 LEU A CD1   1 
ATOM   6966  C  CD2   . LEU A 1 1171 ? 136.291 115.796 102.963 1.00 19.65  ? 1189 LEU A CD2   1 
ATOM   6967  N  N     . ARG A 1 1172 ? 139.934 117.567 105.609 1.00 29.01  ? 1190 ARG A N     1 
ATOM   6968  C  CA    . ARG A 1 1172 ? 141.036 118.373 106.113 1.00 29.01  ? 1190 ARG A CA    1 
ATOM   6969  C  C     . ARG A 1 1172 ? 142.185 118.276 105.125 1.00 29.01  ? 1190 ARG A C     1 
ATOM   6970  O  O     . ARG A 1 1172 ? 142.312 117.283 104.402 1.00 29.01  ? 1190 ARG A O     1 
ATOM   6971  C  CB    . ARG A 1 1172 ? 141.481 117.920 107.510 1.00 29.01  ? 1190 ARG A CB    1 
ATOM   6972  C  CG    . ARG A 1 1172 ? 141.668 116.421 107.647 1.00 29.01  ? 1190 ARG A CG    1 
ATOM   6973  C  CD    . ARG A 1 1172 ? 141.787 116.001 109.105 1.00 29.01  ? 1190 ARG A CD    1 
ATOM   6974  N  NE    . ARG A 1 1172 ? 141.754 114.551 109.249 1.00 29.01  ? 1190 ARG A NE    1 
ATOM   6975  C  CZ    . ARG A 1 1172 ? 141.667 113.911 110.407 1.00 29.01  ? 1190 ARG A CZ    1 
ATOM   6976  N  NH1   . ARG A 1 1172 ? 141.616 114.565 111.555 1.00 29.01  ? 1190 ARG A NH1   1 
ATOM   6977  N  NH2   . ARG A 1 1172 ? 141.621 112.583 110.412 1.00 29.01  ? 1190 ARG A NH2   1 
ATOM   6978  N  N     . LYS A 1 1173 ? 143.014 119.321 105.097 1.00 46.78  ? 1191 LYS A N     1 
ATOM   6979  C  CA    . LYS A 1 1173 ? 144.108 119.372 104.132 1.00 46.78  ? 1191 LYS A CA    1 
ATOM   6980  C  C     . LYS A 1 1173 ? 145.080 118.213 104.322 1.00 46.78  ? 1191 LYS A C     1 
ATOM   6981  O  O     . LYS A 1 1173 ? 145.506 117.585 103.346 1.00 46.78  ? 1191 LYS A O     1 
ATOM   6982  C  CB    . LYS A 1 1173 ? 144.838 120.711 104.240 1.00 46.78  ? 1191 LYS A CB    1 
ATOM   6983  C  CG    . LYS A 1 1173 ? 144.185 121.834 103.456 1.00 46.78  ? 1191 LYS A CG    1 
ATOM   6984  C  CD    . LYS A 1 1173 ? 144.155 121.508 101.972 1.00 46.78  ? 1191 LYS A CD    1 
ATOM   6985  C  CE    . LYS A 1 1173 ? 143.555 122.646 101.164 1.00 46.78  ? 1191 LYS A CE    1 
ATOM   6986  N  NZ    . LYS A 1 1173 ? 143.456 122.297 99.720  1.00 46.78  ? 1191 LYS A NZ    1 
ATOM   6987  N  N     . GLU A 1 1174 ? 145.440 117.910 105.567 1.00 46.64  ? 1192 GLU A N     1 
ATOM   6988  C  CA    . GLU A 1 1174 ? 146.344 116.811 105.869 1.00 46.64  ? 1192 GLU A CA    1 
ATOM   6989  C  C     . GLU A 1 1174 ? 145.706 115.897 106.904 1.00 46.64  ? 1192 GLU A C     1 
ATOM   6990  O  O     . GLU A 1 1174 ? 144.937 116.343 107.759 1.00 46.64  ? 1192 GLU A O     1 
ATOM   6991  C  CB    . GLU A 1 1174 ? 147.697 117.320 106.377 1.00 46.64  ? 1192 GLU A CB    1 
ATOM   6992  C  CG    . GLU A 1 1174 ? 148.440 118.205 105.388 1.00 46.64  ? 1192 GLU A CG    1 
ATOM   6993  C  CD    . GLU A 1 1174 ? 149.832 118.578 105.867 1.00 46.64  ? 1192 GLU A CD    1 
ATOM   6994  O  OE1   . GLU A 1 1174 ? 150.245 118.089 106.940 1.00 46.64  ? 1192 GLU A OE1   1 
ATOM   6995  O  OE2   . GLU A 1 1174 ? 150.513 119.358 105.170 1.00 46.64  ? 1192 GLU A OE2   1 
ATOM   6996  N  N     . VAL A 1 1175 ? 146.036 114.606 106.822 1.00 36.81  ? 1193 VAL A N     1 
ATOM   6997  C  CA    . VAL A 1 1175 ? 145.468 113.625 107.740 1.00 36.81  ? 1193 VAL A CA    1 
ATOM   6998  C  C     . VAL A 1 1175 ? 146.061 113.706 109.136 1.00 36.81  ? 1193 VAL A C     1 
ATOM   6999  O  O     . VAL A 1 1175 ? 145.592 113.005 110.039 1.00 36.81  ? 1193 VAL A O     1 
ATOM   7000  C  CB    . VAL A 1 1175 ? 145.650 112.199 107.186 1.00 36.81  ? 1193 VAL A CB    1 
ATOM   7001  C  CG1   . VAL A 1 1175 ? 144.715 111.967 106.013 1.00 36.81  ? 1193 VAL A CG1   1 
ATOM   7002  C  CG2   . VAL A 1 1175 ? 147.091 111.981 106.769 1.00 36.81  ? 1193 VAL A CG2   1 
ATOM   7003  N  N     . THR A 1 1176 ? 147.083 114.533 109.335 1.00 43.82  ? 1194 THR A N     1 
ATOM   7004  C  CA    . THR A 1 1176 ? 147.695 114.717 110.643 1.00 43.82  ? 1194 THR A CA    1 
ATOM   7005  C  C     . THR A 1 1176 ? 147.071 115.853 111.443 1.00 43.82  ? 1194 THR A C     1 
ATOM   7006  O  O     . THR A 1 1176 ? 147.390 116.000 112.628 1.00 43.82  ? 1194 THR A O     1 
ATOM   7007  C  CB    . THR A 1 1176 ? 149.193 114.990 110.489 1.00 43.82  ? 1194 THR A CB    1 
ATOM   7008  O  OG1   . THR A 1 1176 ? 149.383 116.284 109.904 1.00 43.82  ? 1194 THR A OG1   1 
ATOM   7009  C  CG2   . THR A 1 1176 ? 149.836 113.942 109.596 1.00 43.82  ? 1194 THR A CG2   1 
ATOM   7010  N  N     . MET A 1 1177 ? 146.205 116.656 110.830 1.00 46.22  ? 1195 MET A N     1 
ATOM   7011  C  CA    . MET A 1 1177 ? 145.636 117.811 111.511 1.00 46.22  ? 1195 MET A CA    1 
ATOM   7012  C  C     . MET A 1 1177 ? 144.740 117.378 112.662 1.00 46.22  ? 1195 MET A C     1 
ATOM   7013  O  O     . MET A 1 1177 ? 144.035 116.369 112.577 1.00 46.22  ? 1195 MET A O     1 
ATOM   7014  C  CB    . MET A 1 1177 ? 144.837 118.666 110.529 1.00 46.22  ? 1195 MET A CB    1 
ATOM   7015  C  CG    . MET A 1 1177 ? 145.660 119.260 109.403 1.00 46.22  ? 1195 MET A CG    1 
ATOM   7016  S  SD    . MET A 1 1177 ? 147.018 120.279 110.004 1.00 46.22  ? 1195 MET A SD    1 
ATOM   7017  C  CE    . MET A 1 1177 ? 147.698 120.880 108.460 1.00 46.22  ? 1195 MET A CE    1 
ATOM   7018  N  N     . ASP A 1 1178 ? 144.764 118.156 113.743 1.00 39.77  ? 1196 ASP A N     1 
ATOM   7019  C  CA    . ASP A 1 1178 ? 143.916 117.899 114.898 1.00 39.77  ? 1196 ASP A CA    1 
ATOM   7020  C  C     . ASP A 1 1178 ? 142.824 118.944 115.074 1.00 39.77  ? 1196 ASP A C     1 
ATOM   7021  O  O     . ASP A 1 1178 ? 142.029 118.833 116.012 1.00 39.77  ? 1196 ASP A O     1 
ATOM   7022  C  CB    . ASP A 1 1178 ? 144.764 117.811 116.171 1.00 39.77  ? 1196 ASP A CB    1 
ATOM   7023  C  CG    . ASP A 1 1178 ? 144.246 116.763 117.139 1.00 39.77  ? 1196 ASP A CG    1 
ATOM   7024  O  OD1   . ASP A 1 1178 ? 143.192 116.161 116.849 1.00 39.77  ? 1196 ASP A OD1   1 
ATOM   7025  O  OD2   . ASP A 1 1178 ? 144.894 116.536 118.183 1.00 39.77  ? 1196 ASP A OD2   1 
ATOM   7026  N  N     . CYS A 1 1179 ? 142.770 119.955 114.202 1.00 35.19  ? 1197 CYS A N     1 
ATOM   7027  C  CA    . CYS A 1 1179 ? 141.652 120.900 114.132 1.00 35.19  ? 1197 CYS A CA    1 
ATOM   7028  C  C     . CYS A 1 1179 ? 141.444 121.643 115.452 1.00 35.19  ? 1197 CYS A C     1 
ATOM   7029  O  O     . CYS A 1 1179 ? 140.329 121.739 115.969 1.00 35.19  ? 1197 CYS A O     1 
ATOM   7030  C  CB    . CYS A 1 1179 ? 140.366 120.189 113.702 1.00 35.19  ? 1197 CYS A CB    1 
ATOM   7031  S  SG    . CYS A 1 1179 ? 140.520 119.208 112.196 1.00 35.19  ? 1197 CYS A SG    1 
ATOM   7032  N  N     . LYS A 1 1180 ? 142.531 122.176 115.998 1.00 30.69  ? 1198 LYS A N     1 
ATOM   7033  C  CA    . LYS A 1 1180 ? 142.450 122.984 117.208 1.00 30.69  ? 1198 LYS A CA    1 
ATOM   7034  C  C     . LYS A 1 1180 ? 142.091 124.416 116.833 1.00 30.69  ? 1198 LYS A C     1 
ATOM   7035  O  O     . LYS A 1 1180 ? 142.852 125.086 116.129 1.00 30.69  ? 1198 LYS A O     1 
ATOM   7036  C  CB    . LYS A 1 1180 ? 143.769 122.942 117.974 1.00 30.69  ? 1198 LYS A CB    1 
ATOM   7037  C  CG    . LYS A 1 1180 ? 143.880 121.784 118.944 1.00 30.69  ? 1198 LYS A CG    1 
ATOM   7038  C  CD    . LYS A 1 1180 ? 145.235 121.755 119.623 1.00 30.69  ? 1198 LYS A CD    1 
ATOM   7039  C  CE    . LYS A 1 1180 ? 145.269 120.707 120.720 1.00 30.69  ? 1198 LYS A CE    1 
ATOM   7040  N  NZ    . LYS A 1 1180 ? 144.851 119.372 120.216 1.00 30.69  ? 1198 LYS A NZ    1 
ATOM   7041  N  N     . THR A 1 1181 ? 140.934 124.874 117.289 1.00 26.03  ? 1199 THR A N     1 
ATOM   7042  C  CA    . THR A 1 1181 ? 140.424 126.213 117.046 1.00 26.03  ? 1199 THR A CA    1 
ATOM   7043  C  C     . THR A 1 1181 ? 139.977 126.806 118.371 1.00 26.03  ? 1199 THR A C     1 
ATOM   7044  O  O     . THR A 1 1181 ? 139.797 126.078 119.352 1.00 26.03  ? 1199 THR A O     1 
ATOM   7045  C  CB    . THR A 1 1181 ? 139.245 126.208 116.058 1.00 26.03  ? 1199 THR A CB    1 
ATOM   7046  O  OG1   . THR A 1 1181 ? 138.083 125.668 116.699 1.00 26.03  ? 1199 THR A OG1   1 
ATOM   7047  C  CG2   . THR A 1 1181 ? 139.566 125.376 114.828 1.00 26.03  ? 1199 THR A CG2   1 
ATOM   7048  N  N     . PRO A 1 1182 ? 139.815 128.131 118.446 1.00 23.80  ? 1200 PRO A N     1 
ATOM   7049  C  CA    . PRO A 1 1182 ? 139.259 128.720 119.673 1.00 23.80  ? 1200 PRO A CA    1 
ATOM   7050  C  C     . PRO A 1 1182 ? 137.920 128.131 120.079 1.00 23.80  ? 1200 PRO A C     1 
ATOM   7051  O  O     . PRO A 1 1182 ? 137.563 128.191 121.261 1.00 23.80  ? 1200 PRO A O     1 
ATOM   7052  C  CB    . PRO A 1 1182 ? 139.142 130.205 119.316 1.00 23.80  ? 1200 PRO A CB    1 
ATOM   7053  C  CG    . PRO A 1 1182 ? 140.249 130.425 118.353 1.00 23.80  ? 1200 PRO A CG    1 
ATOM   7054  C  CD    . PRO A 1 1182 ? 140.351 129.162 117.540 1.00 23.80  ? 1200 PRO A CD    1 
ATOM   7055  N  N     . SER A 1 1183 ? 137.161 127.571 119.139 1.00 28.55  ? 1201 SER A N     1 
ATOM   7056  C  CA    . SER A 1 1183 ? 135.953 126.834 119.477 1.00 28.55  ? 1201 SER A CA    1 
ATOM   7057  C  C     . SER A 1 1183 ? 136.204 125.345 119.668 1.00 28.55  ? 1201 SER A C     1 
ATOM   7058  O  O     . SER A 1 1183 ? 135.283 124.624 120.066 1.00 28.55  ? 1201 SER A O     1 
ATOM   7059  C  CB    . SER A 1 1183 ? 134.890 127.026 118.393 1.00 28.55  ? 1201 SER A CB    1 
ATOM   7060  O  OG    . SER A 1 1183 ? 135.110 126.148 117.304 1.00 28.55  ? 1201 SER A OG    1 
ATOM   7061  N  N     . ASN A 1 1184 ? 137.417 124.871 119.389 1.00 32.42  ? 1202 ASN A N     1 
ATOM   7062  C  CA    . ASN A 1 1184 ? 137.771 123.457 119.526 1.00 32.42  ? 1202 ASN A CA    1 
ATOM   7063  C  C     . ASN A 1 1184 ? 139.147 123.360 120.169 1.00 32.42  ? 1202 ASN A C     1 
ATOM   7064  O  O     . ASN A 1 1184 ? 140.121 122.933 119.538 1.00 32.42  ? 1202 ASN A O     1 
ATOM   7065  C  CB    . ASN A 1 1184 ? 137.745 122.762 118.164 1.00 32.42  ? 1202 ASN A CB    1 
ATOM   7066  C  CG    . ASN A 1 1184 ? 137.796 121.261 118.275 1.00 32.42  ? 1202 ASN A CG    1 
ATOM   7067  O  OD1   . ASN A 1 1184 ? 137.616 120.700 119.354 1.00 32.42  ? 1202 ASN A OD1   1 
ATOM   7068  N  ND2   . ASN A 1 1184 ? 138.032 120.595 117.153 1.00 32.42  ? 1202 ASN A ND2   1 
ATOM   7069  N  N     . PRO A 1 1185 ? 139.266 123.758 121.439 1.00 31.67  ? 1203 PRO A N     1 
ATOM   7070  C  CA    . PRO A 1 1185 ? 140.602 123.845 122.046 1.00 31.67  ? 1203 PRO A CA    1 
ATOM   7071  C  C     . PRO A 1 1185 ? 141.258 122.497 122.280 1.00 31.67  ? 1203 PRO A C     1 
ATOM   7072  O  O     . PRO A 1 1185 ? 142.492 122.414 122.261 1.00 31.67  ? 1203 PRO A O     1 
ATOM   7073  C  CB    . PRO A 1 1185 ? 140.336 124.578 123.366 1.00 31.67  ? 1203 PRO A CB    1 
ATOM   7074  C  CG    . PRO A 1 1185 ? 138.938 124.213 123.706 1.00 31.67  ? 1203 PRO A CG    1 
ATOM   7075  C  CD    . PRO A 1 1185 ? 138.200 124.087 122.401 1.00 31.67  ? 1203 PRO A CD    1 
ATOM   7076  N  N     . THR A 1 1186 ? 140.480 121.439 122.498 1.00 35.36  ? 1204 THR A N     1 
ATOM   7077  C  CA    . THR A 1 1186 ? 141.050 120.139 122.823 1.00 35.36  ? 1204 THR A CA    1 
ATOM   7078  C  C     . THR A 1 1186 ? 141.508 119.359 121.598 1.00 35.36  ? 1204 THR A C     1 
ATOM   7079  O  O     . THR A 1 1186 ? 142.147 118.315 121.757 1.00 35.36  ? 1204 THR A O     1 
ATOM   7080  C  CB    . THR A 1 1186 ? 140.036 119.299 123.598 1.00 35.36  ? 1204 THR A CB    1 
ATOM   7081  O  OG1   . THR A 1 1186 ? 138.930 118.982 122.747 1.00 35.36  ? 1204 THR A OG1   1 
ATOM   7082  C  CG2   . THR A 1 1186 ? 139.530 120.066 124.808 1.00 35.36  ? 1204 THR A CG2   1 
ATOM   7083  N  N     . GLY A 1 1187 ? 141.212 119.832 120.394 1.00 37.81  ? 1205 GLY A N     1 
ATOM   7084  C  CA    . GLY A 1 1187 ? 141.555 119.120 119.182 1.00 37.81  ? 1205 GLY A CA    1 
ATOM   7085  C  C     . GLY A 1 1187 ? 140.416 118.245 118.687 1.00 37.81  ? 1205 GLY A C     1 
ATOM   7086  O  O     . GLY A 1 1187 ? 139.376 118.083 119.331 1.00 37.81  ? 1205 GLY A O     1 
ATOM   7087  N  N     . MET A 1 1188 ? 140.630 117.671 117.503 1.00 38.52  ? 1206 MET A N     1 
ATOM   7088  C  CA    . MET A 1 1188 ? 139.598 116.845 116.888 1.00 38.52  ? 1206 MET A CA    1 
ATOM   7089  C  C     . MET A 1 1188 ? 139.520 115.476 117.552 1.00 38.52  ? 1206 MET A C     1 
ATOM   7090  O  O     . MET A 1 1188 ? 138.433 115.013 117.917 1.00 38.52  ? 1206 MET A O     1 
ATOM   7091  C  CB    . MET A 1 1188 ? 139.867 116.709 115.389 1.00 38.52  ? 1206 MET A CB    1 
ATOM   7092  C  CG    . MET A 1 1188 ? 138.875 115.841 114.635 1.00 38.52  ? 1206 MET A CG    1 
ATOM   7093  S  SD    . MET A 1 1188 ? 137.179 116.440 114.729 1.00 38.52  ? 1206 MET A SD    1 
ATOM   7094  C  CE    . MET A 1 1188 ? 137.382 118.140 114.210 1.00 38.52  ? 1206 MET A CE    1 
ATOM   7095  N  N     . GLU A 1 1189 ? 140.669 114.819 117.729 1.00 38.93  ? 1207 GLU A N     1 
ATOM   7096  C  CA    . GLU A 1 1189 ? 140.676 113.462 118.265 1.00 38.93  ? 1207 GLU A CA    1 
ATOM   7097  C  C     . GLU A 1 1189 ? 140.187 113.425 119.707 1.00 38.93  ? 1207 GLU A C     1 
ATOM   7098  O  O     . GLU A 1 1189 ? 139.427 112.527 120.088 1.00 38.93  ? 1207 GLU A O     1 
ATOM   7099  C  CB    . GLU A 1 1189 ? 142.079 112.869 118.163 1.00 38.93  ? 1207 GLU A CB    1 
ATOM   7100  C  CG    . GLU A 1 1189 ? 142.181 111.439 118.653 1.00 38.93  ? 1207 GLU A CG    1 
ATOM   7101  C  CD    . GLU A 1 1189 ? 143.538 110.833 118.378 1.00 38.93  ? 1207 GLU A CD    1 
ATOM   7102  O  OE1   . GLU A 1 1189 ? 144.472 111.593 118.050 1.00 38.93  ? 1207 GLU A OE1   1 
ATOM   7103  O  OE2   . GLU A 1 1189 ? 143.670 109.596 118.482 1.00 38.93  ? 1207 GLU A OE2   1 
ATOM   7104  N  N     . ARG A 1 1190 ? 140.620 114.385 120.524 1.00 43.40  ? 1208 ARG A N     1 
ATOM   7105  C  CA    . ARG A 1 1190 ? 140.206 114.412 121.923 1.00 43.40  ? 1208 ARG A CA    1 
ATOM   7106  C  C     . ARG A 1 1190 ? 138.706 114.646 122.051 1.00 43.40  ? 1208 ARG A C     1 
ATOM   7107  O  O     . ARG A 1 1190 ? 138.006 113.903 122.747 1.00 43.40  ? 1208 ARG A O     1 
ATOM   7108  C  CB    . ARG A 1 1190 ? 140.985 115.492 122.673 1.00 43.40  ? 1208 ARG A CB    1 
ATOM   7109  C  CG    . ARG A 1 1190 ? 142.479 115.226 122.785 1.00 43.40  ? 1208 ARG A CG    1 
ATOM   7110  C  CD    . ARG A 1 1190 ? 142.777 114.148 123.818 1.00 43.40  ? 1208 ARG A CD    1 
ATOM   7111  N  NE    . ARG A 1 1190 ? 144.206 113.995 124.061 1.00 43.40  ? 1208 ARG A NE    1 
ATOM   7112  C  CZ    . ARG A 1 1190 ? 144.729 113.196 124.981 1.00 43.40  ? 1208 ARG A CZ    1 
ATOM   7113  N  NH1   . ARG A 1 1190 ? 143.965 112.457 125.770 1.00 43.40  ? 1208 ARG A NH1   1 
ATOM   7114  N  NH2   . ARG A 1 1190 ? 146.051 113.136 125.115 1.00 43.40  ? 1208 ARG A NH2   1 
ATOM   7115  N  N     . ARG A 1 1191 ? 138.191 115.672 121.373 1.00 37.03  ? 1209 ARG A N     1 
ATOM   7116  C  CA    . ARG A 1 1191 ? 136.801 116.072 121.565 1.00 37.03  ? 1209 ARG A CA    1 
ATOM   7117  C  C     . ARG A 1 1191 ? 135.843 115.162 120.804 1.00 37.03  ? 1209 ARG A C     1 
ATOM   7118  O  O     . ARG A 1 1191 ? 134.982 114.510 121.403 1.00 37.03  ? 1209 ARG A O     1 
ATOM   7119  C  CB    . ARG A 1 1191 ? 136.613 117.529 121.137 1.00 37.03  ? 1209 ARG A CB    1 
ATOM   7120  C  CG    . ARG A 1 1191 ? 135.483 118.244 121.858 1.00 37.03  ? 1209 ARG A CG    1 
ATOM   7121  C  CD    . ARG A 1 1191 ? 135.545 119.740 121.613 1.00 37.03  ? 1209 ARG A CD    1 
ATOM   7122  N  NE    . ARG A 1 1191 ? 134.641 120.486 122.480 1.00 37.03  ? 1209 ARG A NE    1 
ATOM   7123  C  CZ    . ARG A 1 1191 ? 134.565 121.809 122.514 1.00 37.03  ? 1209 ARG A CZ    1 
ATOM   7124  N  NH1   . ARG A 1 1191 ? 135.320 122.565 121.734 1.00 37.03  ? 1209 ARG A NH1   1 
ATOM   7125  N  NH2   . ARG A 1 1191 ? 133.712 122.389 123.354 1.00 37.03  ? 1209 ARG A NH2   1 
ATOM   7126  N  N     . TYR A 1 1192 ? 135.979 115.105 119.481 1.00 35.15  ? 1210 TYR A N     1 
ATOM   7127  C  CA    . TYR A 1 1192 ? 135.011 114.421 118.637 1.00 35.15  ? 1210 TYR A CA    1 
ATOM   7128  C  C     . TYR A 1 1192 ? 135.371 112.965 118.366 1.00 35.15  ? 1210 TYR A C     1 
ATOM   7129  O  O     . TYR A 1 1192 ? 134.588 112.261 117.720 1.00 35.15  ? 1210 TYR A O     1 
ATOM   7130  C  CB    . TYR A 1 1192 ? 134.850 115.180 117.317 1.00 35.15  ? 1210 TYR A CB    1 
ATOM   7131  C  CG    . TYR A 1 1192 ? 134.502 116.643 117.506 1.00 35.15  ? 1210 TYR A CG    1 
ATOM   7132  C  CD1   . TYR A 1 1192 ? 133.202 117.039 117.786 1.00 35.15  ? 1210 TYR A CD1   1 
ATOM   7133  C  CD2   . TYR A 1 1192 ? 135.476 117.626 117.412 1.00 35.15  ? 1210 TYR A CD2   1 
ATOM   7134  C  CE1   . TYR A 1 1192 ? 132.883 118.372 117.963 1.00 35.15  ? 1210 TYR A CE1   1 
ATOM   7135  C  CE2   . TYR A 1 1192 ? 135.165 118.961 117.584 1.00 35.15  ? 1210 TYR A CE2   1 
ATOM   7136  C  CZ    . TYR A 1 1192 ? 133.869 119.328 117.860 1.00 35.15  ? 1210 TYR A CZ    1 
ATOM   7137  O  OH    . TYR A 1 1192 ? 133.564 120.658 118.033 1.00 35.15  ? 1210 TYR A OH    1 
ATOM   7138  N  N     . GLY A 1 1193 ? 136.517 112.494 118.850 1.00 35.34  ? 1211 GLY A N     1 
ATOM   7139  C  CA    . GLY A 1 1193 ? 136.879 111.096 118.713 1.00 35.34  ? 1211 GLY A CA    1 
ATOM   7140  C  C     . GLY A 1 1193 ? 137.114 110.637 117.289 1.00 35.34  ? 1211 GLY A C     1 
ATOM   7141  O  O     . GLY A 1 1193 ? 136.619 109.581 116.885 1.00 35.34  ? 1211 GLY A O     1 
ATOM   7142  N  N     . ILE A 1 1194 ? 137.863 111.418 116.519 1.00 31.55  ? 1212 ILE A N     1 
ATOM   7143  C  CA    . ILE A 1 1194 ? 138.154 111.114 115.124 1.00 31.55  ? 1212 ILE A CA    1 
ATOM   7144  C  C     . ILE A 1 1194 ? 139.624 110.706 115.032 1.00 31.55  ? 1212 ILE A C     1 
ATOM   7145  O  O     . ILE A 1 1194 ? 140.511 111.569 115.109 1.00 31.55  ? 1212 ILE A O     1 
ATOM   7146  C  CB    . ILE A 1 1194 ? 137.848 112.306 114.208 1.00 31.55  ? 1212 ILE A CB    1 
ATOM   7147  C  CG1   . ILE A 1 1194 ? 136.355 112.639 114.237 1.00 31.55  ? 1212 ILE A CG1   1 
ATOM   7148  C  CG2   . ILE A 1 1194 ? 138.293 112.015 112.786 1.00 31.55  ? 1212 ILE A CG2   1 
ATOM   7149  C  CD1   . ILE A 1 1194 ? 135.480 111.587 113.600 1.00 31.55  ? 1212 ILE A CD1   1 
ATOM   7150  N  N     . PRO A 1 1195 ? 139.930 109.420 114.880 1.00 31.52  ? 1213 PRO A N     1 
ATOM   7151  C  CA    . PRO A 1 1195 ? 141.328 109.010 114.724 1.00 31.52  ? 1213 PRO A CA    1 
ATOM   7152  C  C     . PRO A 1 1195 ? 141.908 109.499 113.409 1.00 31.52  ? 1213 PRO A C     1 
ATOM   7153  O  O     . PRO A 1 1195 ? 141.199 109.673 112.416 1.00 31.52  ? 1213 PRO A O     1 
ATOM   7154  C  CB    . PRO A 1 1195 ? 141.256 107.479 114.759 1.00 31.52  ? 1213 PRO A CB    1 
ATOM   7155  C  CG    . PRO A 1 1195 ? 139.960 107.171 115.432 1.00 31.52  ? 1213 PRO A CG    1 
ATOM   7156  C  CD    . PRO A 1 1195 ? 139.030 108.264 115.008 1.00 31.52  ? 1213 PRO A CD    1 
ATOM   7157  N  N     . GLN A 1 1196 ? 143.218 109.719 113.415 1.00 35.57  ? 1214 GLN A N     1 
ATOM   7158  C  CA    . GLN A 1 1196 ? 143.904 110.192 112.222 1.00 35.57  ? 1214 GLN A CA    1 
ATOM   7159  C  C     . GLN A 1 1196 ? 143.883 109.133 111.125 1.00 35.57  ? 1214 GLN A C     1 
ATOM   7160  O  O     . GLN A 1 1196 ? 143.837 107.929 111.390 1.00 35.57  ? 1214 GLN A O     1 
ATOM   7161  C  CB    . GLN A 1 1196 ? 145.345 110.569 112.551 1.00 35.57  ? 1214 GLN A CB    1 
ATOM   7162  C  CG    . GLN A 1 1196 ? 145.472 111.711 113.530 1.00 35.57  ? 1214 GLN A CG    1 
ATOM   7163  C  CD    . GLN A 1 1196 ? 146.911 111.994 113.883 1.00 35.57  ? 1214 GLN A CD    1 
ATOM   7164  O  OE1   . GLN A 1 1196 ? 147.816 111.282 113.449 1.00 35.57  ? 1214 GLN A OE1   1 
ATOM   7165  N  NE2   . GLN A 1 1196 ? 147.135 113.036 114.673 1.00 35.57  ? 1214 GLN A NE2   1 
ATOM   7166  N  N     . GLY A 1 1197 ? 143.911 109.601 109.876 1.00 36.10  ? 1215 GLY A N     1 
ATOM   7167  C  CA    . GLY A 1 1197 ? 143.944 108.729 108.725 1.00 36.10  ? 1215 GLY A CA    1 
ATOM   7168  C  C     . GLY A 1 1197 ? 145.337 108.628 108.122 1.00 36.10  ? 1215 GLY A C     1 
ATOM   7169  O  O     . GLY A 1 1197 ? 146.297 109.241 108.580 1.00 36.10  ? 1215 GLY A O     1 
ATOM   7170  N  N     . GLU A 1 1198 ? 145.430 107.831 107.061 1.00 33.78  ? 1216 GLU A N     1 
ATOM   7171  C  CA    . GLU A 1 1198 ? 146.704 107.509 106.430 1.00 33.78  ? 1216 GLU A CA    1 
ATOM   7172  C  C     . GLU A 1 1198 ? 146.769 108.118 105.038 1.00 33.78  ? 1216 GLU A C     1 
ATOM   7173  O  O     . GLU A 1 1198 ? 145.889 107.874 104.206 1.00 33.78  ? 1216 GLU A O     1 
ATOM   7174  C  CB    . GLU A 1 1198 ? 146.909 105.997 106.365 1.00 33.78  ? 1216 GLU A CB    1 
ATOM   7175  C  CG    . GLU A 1 1198 ? 145.669 105.213 105.994 1.00 33.78  ? 1216 GLU A CG    1 
ATOM   7176  C  CD    . GLU A 1 1198 ? 145.923 103.724 105.975 1.00 33.78  ? 1216 GLU A CD    1 
ATOM   7177  O  OE1   . GLU A 1 1198 ? 147.104 103.329 105.892 1.00 33.78  ? 1216 GLU A OE1   1 
ATOM   7178  O  OE2   . GLU A 1 1198 ? 144.947 102.948 106.051 1.00 33.78  ? 1216 GLU A OE2   1 
ATOM   7179  N  N     . ALA A 1 1199 ? 147.813 108.903 104.789 1.00 30.45  ? 1217 ALA A N     1 
ATOM   7180  C  CA    . ALA A 1 1199 ? 148.084 109.457 103.465 1.00 30.45  ? 1217 ALA A CA    1 
ATOM   7181  C  C     . ALA A 1 1199 ? 148.986 108.473 102.733 1.00 30.45  ? 1217 ALA A C     1 
ATOM   7182  O  O     . ALA A 1 1199 ? 150.200 108.448 102.942 1.00 30.45  ? 1217 ALA A O     1 
ATOM   7183  C  CB    . ALA A 1 1199 ? 148.722 110.836 103.572 1.00 30.45  ? 1217 ALA A CB    1 
ATOM   7184  N  N     . LEU A 1 1200 ? 148.391 107.665 101.864 1.00 35.57  ? 1218 LEU A N     1 
ATOM   7185  C  CA    . LEU A 1 1200 ? 149.105 106.583 101.202 1.00 35.57  ? 1218 LEU A CA    1 
ATOM   7186  C  C     . LEU A 1 1200 ? 149.935 107.122 100.042 1.00 35.57  ? 1218 LEU A C     1 
ATOM   7187  O  O     . LEU A 1 1200 ? 150.174 108.324 99.907  1.00 35.57  ? 1218 LEU A O     1 
ATOM   7188  C  CB    . LEU A 1 1200 ? 148.129 105.514 100.727 1.00 35.57  ? 1218 LEU A CB    1 
ATOM   7189  C  CG    . LEU A 1 1200 ? 147.361 104.757 101.802 1.00 35.57  ? 1218 LEU A CG    1 
ATOM   7190  C  CD1   . LEU A 1 1200 ? 146.599 103.626 101.158 1.00 35.57  ? 1218 LEU A CD1   1 
ATOM   7191  C  CD2   . LEU A 1 1200 ? 148.306 104.234 102.865 1.00 35.57  ? 1218 LEU A CD2   1 
ATOM   7192  N  N     . ASP A 1 1201 ? 150.411 106.209 99.204  1.00 47.96  ? 1219 ASP A N     1 
ATOM   7193  C  CA    . ASP A 1 1201 ? 151.182 106.543 98.019  1.00 47.96  ? 1219 ASP A CA    1 
ATOM   7194  C  C     . ASP A 1 1201 ? 150.990 105.414 97.019  1.00 47.96  ? 1219 ASP A C     1 
ATOM   7195  O  O     . ASP A 1 1201 ? 150.496 104.338 97.361  1.00 47.96  ? 1219 ASP A O     1 
ATOM   7196  C  CB    . ASP A 1 1201 ? 152.662 106.757 98.356  1.00 47.96  ? 1219 ASP A CB    1 
ATOM   7197  C  CG    . ASP A 1 1201 ? 153.415 107.469 97.252  1.00 47.96  ? 1219 ASP A CG    1 
ATOM   7198  O  OD1   . ASP A 1 1201 ? 152.802 107.759 96.202  1.00 47.96  ? 1219 ASP A OD1   1 
ATOM   7199  O  OD2   . ASP A 1 1201 ? 154.620 107.742 97.434  1.00 47.96  ? 1219 ASP A OD2   1 
ATOM   7200  N  N     . ILE A 1 1202 ? 151.389 105.666 95.771  1.00 45.64  ? 1220 ILE A N     1 
ATOM   7201  C  CA    . ILE A 1 1202 ? 151.099 104.717 94.699  1.00 45.64  ? 1220 ILE A CA    1 
ATOM   7202  C  C     . ILE A 1 1202 ? 151.771 103.374 94.963  1.00 45.64  ? 1220 ILE A C     1 
ATOM   7203  O  O     . ILE A 1 1202 ? 151.164 102.314 94.770  1.00 45.64  ? 1220 ILE A O     1 
ATOM   7204  C  CB    . ILE A 1 1202 ? 151.506 105.307 93.335  1.00 45.64  ? 1220 ILE A CB    1 
ATOM   7205  C  CG1   . ILE A 1 1202 ? 151.431 104.235 92.247  1.00 45.64  ? 1220 ILE A CG1   1 
ATOM   7206  C  CG2   . ILE A 1 1202 ? 152.880 105.958 93.407  1.00 45.64  ? 1220 ILE A CG2   1 
ATOM   7207  C  CD1   . ILE A 1 1202 ? 150.036 103.678 92.039  1.00 45.64  ? 1220 ILE A CD1   1 
ATOM   7208  N  N     . TYR A 1 1203 ? 153.028 103.391 95.413  1.00 48.34  ? 1221 TYR A N     1 
ATOM   7209  C  CA    . TYR A 1 1203 ? 153.725 102.140 95.698  1.00 48.34  ? 1221 TYR A CA    1 
ATOM   7210  C  C     . TYR A 1 1203 ? 153.058 101.381 96.838  1.00 48.34  ? 1221 TYR A C     1 
ATOM   7211  O  O     . TYR A 1 1203 ? 152.881 100.158 96.764  1.00 48.34  ? 1221 TYR A O     1 
ATOM   7212  C  CB    . TYR A 1 1203 ? 155.188 102.428 96.022  1.00 48.34  ? 1221 TYR A CB    1 
ATOM   7213  C  CG    . TYR A 1 1203 ? 155.780 103.503 95.147  1.00 48.34  ? 1221 TYR A CG    1 
ATOM   7214  C  CD1   . TYR A 1 1203 ? 156.128 103.238 93.832  1.00 48.34  ? 1221 TYR A CD1   1 
ATOM   7215  C  CD2   . TYR A 1 1203 ? 155.983 104.785 95.632  1.00 48.34  ? 1221 TYR A CD2   1 
ATOM   7216  C  CE1   . TYR A 1 1203 ? 156.665 104.218 93.027  1.00 48.34  ? 1221 TYR A CE1   1 
ATOM   7217  C  CE2   . TYR A 1 1203 ? 156.520 105.771 94.834  1.00 48.34  ? 1221 TYR A CE2   1 
ATOM   7218  C  CZ    . TYR A 1 1203 ? 156.859 105.483 93.534  1.00 48.34  ? 1221 TYR A CZ    1 
ATOM   7219  O  OH    . TYR A 1 1203 ? 157.394 106.467 92.737  1.00 48.34  ? 1221 TYR A OH    1 
ATOM   7220  N  N     . GLN A 1 1204 ? 152.677 102.091 97.901  1.00 52.76  ? 1222 GLN A N     1 
ATOM   7221  C  CA    . GLN A 1 1204 ? 151.969 101.453 99.007  1.00 52.76  ? 1222 GLN A CA    1 
ATOM   7222  C  C     . GLN A 1 1204 ? 150.607 100.937 98.562  1.00 52.76  ? 1222 GLN A C     1 
ATOM   7223  O  O     . GLN A 1 1204 ? 150.166 99.869  99.000  1.00 52.76  ? 1222 GLN A O     1 
ATOM   7224  C  CB    . GLN A 1 1204 ? 151.826 102.438 100.166 1.00 52.76  ? 1222 GLN A CB    1 
ATOM   7225  C  CG    . GLN A 1 1204 ? 153.060 103.296 100.386 1.00 52.76  ? 1222 GLN A CG    1 
ATOM   7226  C  CD    . GLN A 1 1204 ? 152.973 104.139 101.639 1.00 52.76  ? 1222 GLN A CD    1 
ATOM   7227  O  OE1   . GLN A 1 1204 ? 152.376 103.733 102.635 1.00 52.76  ? 1222 GLN A OE1   1 
ATOM   7228  N  NE2   . GLN A 1 1204 ? 153.569 105.324 101.596 1.00 52.76  ? 1222 GLN A NE2   1 
ATOM   7229  N  N     . ILE A 1 1205 ? 149.930 101.681 97.687  1.00 48.05  ? 1223 ILE A N     1 
ATOM   7230  C  CA    . ILE A 1 1205 ? 148.639 101.236 97.171  1.00 48.05  ? 1223 ILE A CA    1 
ATOM   7231  C  C     . ILE A 1 1205 ? 148.800 99.945  96.381  1.00 48.05  ? 1223 ILE A C     1 
ATOM   7232  O  O     . ILE A 1 1205 ? 147.997 99.012  96.515  1.00 48.05  ? 1223 ILE A O     1 
ATOM   7233  C  CB    . ILE A 1 1205 ? 147.999 102.349 96.321  1.00 48.05  ? 1223 ILE A CB    1 
ATOM   7234  C  CG1   . ILE A 1 1205 ? 147.524 103.491 97.219  1.00 48.05  ? 1223 ILE A CG1   1 
ATOM   7235  C  CG2   . ILE A 1 1205 ? 146.852 101.800 95.506  1.00 48.05  ? 1223 ILE A CG2   1 
ATOM   7236  C  CD1   . ILE A 1 1205 ? 147.371 104.806 96.501  1.00 48.05  ? 1223 ILE A CD1   1 
ATOM   7237  N  N     . ILE A 1 1206 ? 149.842 99.868  95.551  1.00 51.49  ? 1224 ILE A N     1 
ATOM   7238  C  CA    . ILE A 1 1206 ? 150.098 98.654  94.783  1.00 51.49  ? 1224 ILE A CA    1 
ATOM   7239  C  C     . ILE A 1 1206 ? 150.420 97.492  95.712  1.00 51.49  ? 1224 ILE A C     1 
ATOM   7240  O  O     . ILE A 1 1206 ? 149.939 96.371  95.514  1.00 51.49  ? 1224 ILE A O     1 
ATOM   7241  C  CB    . ILE A 1 1206 ? 151.230 98.891  93.767  1.00 51.49  ? 1224 ILE A CB    1 
ATOM   7242  C  CG1   . ILE A 1 1206 ? 150.822 99.949  92.745  1.00 51.49  ? 1224 ILE A CG1   1 
ATOM   7243  C  CG2   . ILE A 1 1206 ? 151.593 97.596  93.063  1.00 51.49  ? 1224 ILE A CG2   1 
ATOM   7244  C  CD1   . ILE A 1 1206 ? 151.978 100.468 91.931  1.00 51.49  ? 1224 ILE A CD1   1 
ATOM   7245  N  N     . GLU A 1 1207 ? 151.243 97.735  96.736  1.00 54.20  ? 1225 GLU A N     1 
ATOM   7246  C  CA    . GLU A 1 1207 ? 151.590 96.659  97.660  1.00 54.20  ? 1225 GLU A CA    1 
ATOM   7247  C  C     . GLU A 1 1207 ? 150.370 96.165  98.428  1.00 54.20  ? 1225 GLU A C     1 
ATOM   7248  O  O     . GLU A 1 1207 ? 150.277 94.974  98.745  1.00 54.20  ? 1225 GLU A O     1 
ATOM   7249  C  CB    . GLU A 1 1207 ? 152.693 97.116  98.621  1.00 54.20  ? 1225 GLU A CB    1 
ATOM   7250  C  CG    . GLU A 1 1207 ? 152.209 97.674  99.951  1.00 54.20  ? 1225 GLU A CG    1 
ATOM   7251  C  CD    . GLU A 1 1207 ? 153.336 98.215  100.805 1.00 54.20  ? 1225 GLU A CD    1 
ATOM   7252  O  OE1   . GLU A 1 1207 ? 154.493 98.213  100.334 1.00 54.20  ? 1225 GLU A OE1   1 
ATOM   7253  O  OE2   . GLU A 1 1207 ? 153.066 98.643  101.947 1.00 54.20  ? 1225 GLU A OE2   1 
ATOM   7254  N  N     . LEU A 1 1208 ? 149.426 97.056  98.736  1.00 52.49  ? 1226 LEU A N     1 
ATOM   7255  C  CA    . LEU A 1 1208 ? 148.223 96.639  99.446  1.00 52.49  ? 1226 LEU A CA    1 
ATOM   7256  C  C     . LEU A 1 1208 ? 147.255 95.891  98.535  1.00 52.49  ? 1226 LEU A C     1 
ATOM   7257  O  O     . LEU A 1 1208 ? 146.692 94.866  98.934  1.00 52.49  ? 1226 LEU A O     1 
ATOM   7258  C  CB    . LEU A 1 1208 ? 147.542 97.856  100.072 1.00 52.49  ? 1226 LEU A CB    1 
ATOM   7259  C  CG    . LEU A 1 1208 ? 148.221 98.389  101.334 1.00 52.49  ? 1226 LEU A CG    1 
ATOM   7260  C  CD1   . LEU A 1 1208 ? 148.040 99.889  101.463 1.00 52.49  ? 1226 LEU A CD1   1 
ATOM   7261  C  CD2   . LEU A 1 1208 ? 147.676 97.678  102.562 1.00 52.49  ? 1226 LEU A CD2   1 
ATOM   7262  N  N     . THR A 1 1209 ? 147.052 96.382  97.314  1.00 52.31  ? 1227 THR A N     1 
ATOM   7263  C  CA    . THR A 1 1209 ? 146.066 95.821  96.400  1.00 52.31  ? 1227 THR A CA    1 
ATOM   7264  C  C     . THR A 1 1209 ? 146.657 94.833  95.402  1.00 52.31  ? 1227 THR A C     1 
ATOM   7265  O  O     . THR A 1 1209 ? 145.916 94.311  94.563  1.00 52.31  ? 1227 THR A O     1 
ATOM   7266  C  CB    . THR A 1 1209 ? 145.354 96.946  95.640  1.00 52.31  ? 1227 THR A CB    1 
ATOM   7267  O  OG1   . THR A 1 1209 ? 146.322 97.896  95.179  1.00 52.31  ? 1227 THR A OG1   1 
ATOM   7268  C  CG2   . THR A 1 1209 ? 144.355 97.648  96.538  1.00 52.31  ? 1227 THR A CG2   1 
ATOM   7269  N  N     . LYS A 1 1210 ? 147.963 94.574  95.464  1.00 59.33  ? 1228 LYS A N     1 
ATOM   7270  C  CA    . LYS A 1 1210 ? 148.672 93.730  94.501  1.00 59.33  ? 1228 LYS A CA    1 
ATOM   7271  C  C     . LYS A 1 1210 ? 148.576 94.274  93.078  1.00 59.33  ? 1228 LYS A C     1 
ATOM   7272  O  O     . LYS A 1 1210 ? 148.834 93.548  92.114  1.00 59.33  ? 1228 LYS A O     1 
ATOM   7273  C  CB    . LYS A 1 1210 ? 148.175 92.279  94.552  1.00 59.33  ? 1228 LYS A CB    1 
ATOM   7274  C  CG    . LYS A 1 1210 ? 148.441 91.578  95.875  1.00 59.33  ? 1228 LYS A CG    1 
ATOM   7275  C  CD    . LYS A 1 1210 ? 147.807 90.198  95.902  1.00 59.33  ? 1228 LYS A CD    1 
ATOM   7276  C  CE    . LYS A 1 1210 ? 148.289 89.347  94.739  1.00 59.33  ? 1228 LYS A CE    1 
ATOM   7277  N  NZ    . LYS A 1 1210 ? 147.605 88.027  94.703  1.00 59.33  ? 1228 LYS A NZ    1 
ATOM   7278  N  N     . GLY A 1 1211 ? 148.215 95.548  92.933  1.00 56.70  ? 1229 GLY A N     1 
ATOM   7279  C  CA    . GLY A 1 1211 ? 148.111 96.183  91.637  1.00 56.70  ? 1229 GLY A CA    1 
ATOM   7280  C  C     . GLY A 1 1211 ? 146.809 95.958  90.902  1.00 56.70  ? 1229 GLY A C     1 
ATOM   7281  O  O     . GLY A 1 1211 ? 146.651 96.474  89.789  1.00 56.70  ? 1229 GLY A O     1 
ATOM   7282  N  N     . SER A 1 1212 ? 145.872 95.214  91.480  1.00 51.47  ? 1230 SER A N     1 
ATOM   7283  C  CA    . SER A 1 1212 ? 144.624 94.865  90.820  1.00 51.47  ? 1230 SER A CA    1 
ATOM   7284  C  C     . SER A 1 1212 ? 143.448 95.403  91.619  1.00 51.47  ? 1230 SER A C     1 
ATOM   7285  O  O     . SER A 1 1212 ? 143.447 95.351  92.853  1.00 51.47  ? 1230 SER A O     1 
ATOM   7286  C  CB    . SER A 1 1212 ? 144.495 93.348  90.652  1.00 51.47  ? 1230 SER A CB    1 
ATOM   7287  O  OG    . SER A 1 1212 ? 143.315 93.013  89.943  1.00 51.47  ? 1230 SER A OG    1 
ATOM   7288  N  N     . LEU A 1 1213 ? 142.450 95.924  90.909  1.00 44.42  ? 1231 LEU A N     1 
ATOM   7289  C  CA    . LEU A 1 1213 ? 141.261 96.490  91.528  1.00 44.42  ? 1231 LEU A CA    1 
ATOM   7290  C  C     . LEU A 1 1213 ? 140.150 95.468  91.713  1.00 44.42  ? 1231 LEU A C     1 
ATOM   7291  O  O     . LEU A 1 1213 ? 139.054 95.838  92.146  1.00 44.42  ? 1231 LEU A O     1 
ATOM   7292  C  CB    . LEU A 1 1213 ? 140.732 97.666  90.700  1.00 44.42  ? 1231 LEU A CB    1 
ATOM   7293  C  CG    . LEU A 1 1213 ? 141.724 98.738  90.248  1.00 44.42  ? 1231 LEU A CG    1 
ATOM   7294  C  CD1   . LEU A 1 1213 ? 142.319 98.381  88.895  1.00 44.42  ? 1231 LEU A CD1   1 
ATOM   7295  C  CD2   . LEU A 1 1213 ? 141.059 100.102 90.201  1.00 44.42  ? 1231 LEU A CD2   1 
ATOM   7296  N  N     . GLU A 1 1214 ? 140.397 94.205  91.387  1.00 48.44  ? 1232 GLU A N     1 
ATOM   7297  C  CA    . GLU A 1 1214 ? 139.384 93.181  91.568  1.00 48.44  ? 1232 GLU A CA    1 
ATOM   7298  C  C     . GLU A 1 1214 ? 139.153 92.917  93.053  1.00 48.44  ? 1232 GLU A C     1 
ATOM   7299  O  O     . GLU A 1 1214 ? 139.967 93.269  93.911  1.00 48.44  ? 1232 GLU A O     1 
ATOM   7300  C  CB    . GLU A 1 1214 ? 139.795 91.892  90.856  1.00 48.44  ? 1232 GLU A CB    1 
ATOM   7301  C  CG    . GLU A 1 1214 ? 139.972 92.043  89.352  1.00 48.44  ? 1232 GLU A CG    1 
ATOM   7302  C  CD    . GLU A 1 1214 ? 138.659 92.267  88.624  1.00 48.44  ? 1232 GLU A CD    1 
ATOM   7303  O  OE1   . GLU A 1 1214 ? 137.595 91.931  89.188  1.00 48.44  ? 1232 GLU A OE1   1 
ATOM   7304  O  OE2   . GLU A 1 1214 ? 138.689 92.779  87.486  1.00 48.44  ? 1232 GLU A OE2   1 
ATOM   7305  N  N     . LYS A 1 1215 ? 138.019 92.294  93.350  1.00 46.28  ? 1233 LYS A N     1 
ATOM   7306  C  CA    . LYS A 1 1215 ? 137.650 92.005  94.729  1.00 46.28  ? 1233 LYS A CA    1 
ATOM   7307  C  C     . LYS A 1 1215 ? 137.967 90.557  95.092  1.00 46.28  ? 1233 LYS A C     1 
ATOM   7308  O  O     . LYS A 1 1215 ? 138.932 89.979  94.592  1.00 46.28  ? 1233 LYS A O     1 
ATOM   7309  C  CB    . LYS A 1 1215 ? 136.166 92.294  94.953  1.00 46.28  ? 1233 LYS A CB    1 
ATOM   7310  C  CG    . LYS A 1 1215 ? 135.735 92.254  96.406  1.00 46.28  ? 1233 LYS A CG    1 
ATOM   7311  C  CD    . LYS A 1 1215 ? 134.283 92.671  96.553  1.00 46.28  ? 1233 LYS A CD    1 
ATOM   7312  C  CE    . LYS A 1 1215 ? 133.876 92.757  98.014  1.00 46.28  ? 1233 LYS A CE    1 
ATOM   7313  N  NZ    . LYS A 1 1215 ? 132.456 93.180  98.175  1.00 46.28  ? 1233 LYS A NZ    1 
ATOM   7314  N  N     . GLU B 2 26   ? 155.692 147.529 142.651 1.00 38.15  ? 41   GLU B N     1 
ATOM   7315  C  CA    . GLU B 2 26   ? 155.569 146.647 143.806 1.00 38.15  ? 41   GLU B CA    1 
ATOM   7316  C  C     . GLU B 2 26   ? 154.898 145.332 143.427 1.00 38.15  ? 41   GLU B C     1 
ATOM   7317  O  O     . GLU B 2 26   ? 153.920 145.316 142.682 1.00 38.15  ? 41   GLU B O     1 
ATOM   7318  C  CB    . GLU B 2 26   ? 154.783 147.334 144.924 1.00 38.15  ? 41   GLU B CB    1 
ATOM   7319  C  CG    . GLU B 2 26   ? 154.500 146.441 146.122 1.00 38.15  ? 41   GLU B CG    1 
ATOM   7320  C  CD    . GLU B 2 26   ? 153.712 147.146 147.209 1.00 38.15  ? 41   GLU B CD    1 
ATOM   7321  O  OE1   . GLU B 2 26   ? 153.742 148.394 147.258 1.00 38.15  ? 41   GLU B OE1   1 
ATOM   7322  O  OE2   . GLU B 2 26   ? 153.060 146.448 148.014 1.00 38.15  ? 41   GLU B OE2   1 
ATOM   7323  N  N     . ALA B 2 27   ? 155.436 144.231 143.943 1.00 35.00  ? 42   ALA B N     1 
ATOM   7324  C  CA    . ALA B 2 27   ? 154.852 142.926 143.690 1.00 35.00  ? 42   ALA B CA    1 
ATOM   7325  C  C     . ALA B 2 27   ? 153.484 142.817 144.355 1.00 35.00  ? 42   ALA B C     1 
ATOM   7326  O  O     . ALA B 2 27   ? 153.162 143.540 145.301 1.00 35.00  ? 42   ALA B O     1 
ATOM   7327  C  CB    . ALA B 2 27   ? 155.774 141.816 144.193 1.00 35.00  ? 42   ALA B CB    1 
ATOM   7328  N  N     . LEU B 2 28   ? 152.666 141.901 143.834 1.00 28.51  ? 43   LEU B N     1 
ATOM   7329  C  CA    . LEU B 2 28   ? 151.328 141.713 144.383 1.00 28.51  ? 43   LEU B CA    1 
ATOM   7330  C  C     . LEU B 2 28   ? 151.379 141.249 145.830 1.00 28.51  ? 43   LEU B C     1 
ATOM   7331  O  O     . LEU B 2 28   ? 150.594 141.716 146.664 1.00 28.51  ? 43   LEU B O     1 
ATOM   7332  C  CB    . LEU B 2 28   ? 150.543 140.705 143.549 1.00 28.51  ? 43   LEU B CB    1 
ATOM   7333  C  CG    . LEU B 2 28   ? 149.258 140.277 144.259 1.00 28.51  ? 43   LEU B CG    1 
ATOM   7334  C  CD1   . LEU B 2 28   ? 148.156 141.294 144.026 1.00 28.51  ? 43   LEU B CD1   1 
ATOM   7335  C  CD2   . LEU B 2 28   ? 148.824 138.883 143.863 1.00 28.51  ? 43   LEU B CD2   1 
ATOM   7336  N  N     . VAL B 2 29   ? 152.289 140.327 146.148 1.00 31.12  ? 44   VAL B N     1 
ATOM   7337  C  CA    . VAL B 2 29   ? 152.279 139.714 147.472 1.00 31.12  ? 44   VAL B CA    1 
ATOM   7338  C  C     . VAL B 2 29   ? 152.599 140.745 148.543 1.00 31.12  ? 44   VAL B C     1 
ATOM   7339  O  O     . VAL B 2 29   ? 152.053 140.693 149.651 1.00 31.12  ? 44   VAL B O     1 
ATOM   7340  C  CB    . VAL B 2 29   ? 153.252 138.523 147.521 1.00 31.12  ? 44   VAL B CB    1 
ATOM   7341  C  CG1   . VAL B 2 29   ? 152.967 137.669 148.744 1.00 31.12  ? 44   VAL B CG1   1 
ATOM   7342  C  CG2   . VAL B 2 29   ? 153.143 137.699 146.251 1.00 31.12  ? 44   VAL B CG2   1 
ATOM   7343  N  N     . ASP B 2 30   ? 153.473 141.704 148.234 1.00 34.91  ? 45   ASP B N     1 
ATOM   7344  C  CA    . ASP B 2 30   ? 153.716 142.798 149.169 1.00 34.91  ? 45   ASP B CA    1 
ATOM   7345  C  C     . ASP B 2 30   ? 152.436 143.575 149.445 1.00 34.91  ? 45   ASP B C     1 
ATOM   7346  O  O     . ASP B 2 30   ? 152.141 143.914 150.597 1.00 34.91  ? 45   ASP B O     1 
ATOM   7347  C  CB    . ASP B 2 30   ? 154.796 143.731 148.621 1.00 34.91  ? 45   ASP B CB    1 
ATOM   7348  C  CG    . ASP B 2 30   ? 156.180 143.114 148.666 1.00 34.91  ? 45   ASP B CG    1 
ATOM   7349  O  OD1   . ASP B 2 30   ? 156.337 142.037 149.278 1.00 34.91  ? 45   ASP B OD1   1 
ATOM   7350  O  OD2   . ASP B 2 30   ? 157.111 143.711 148.086 1.00 34.91  ? 45   ASP B OD2   1 
ATOM   7351  N  N     . LEU B 2 31   ? 151.662 143.862 148.397 1.00 28.64  ? 46   LEU B N     1 
ATOM   7352  C  CA    . LEU B 2 31   ? 150.404 144.582 148.571 1.00 28.64  ? 46   LEU B CA    1 
ATOM   7353  C  C     . LEU B 2 31   ? 149.416 143.780 149.408 1.00 28.64  ? 46   LEU B C     1 
ATOM   7354  O  O     . LEU B 2 31   ? 148.827 144.300 150.362 1.00 28.64  ? 46   LEU B O     1 
ATOM   7355  C  CB    . LEU B 2 31   ? 149.805 144.910 147.205 1.00 28.64  ? 46   LEU B CB    1 
ATOM   7356  C  CG    . LEU B 2 31   ? 148.365 145.415 147.225 1.00 28.64  ? 46   LEU B CG    1 
ATOM   7357  C  CD1   . LEU B 2 31   ? 148.306 146.759 147.918 1.00 28.64  ? 46   LEU B CD1   1 
ATOM   7358  C  CD2   . LEU B 2 31   ? 147.795 145.500 145.818 1.00 28.64  ? 46   LEU B CD2   1 
ATOM   7359  N  N     . CYS B 2 32   ? 149.226 142.505 149.069 1.00 26.39  ? 47   CYS B N     1 
ATOM   7360  C  CA    . CYS B 2 32   ? 148.273 141.673 149.791 1.00 26.39  ? 47   CYS B CA    1 
ATOM   7361  C  C     . CYS B 2 32   ? 148.721 141.383 151.216 1.00 26.39  ? 47   CYS B C     1 
ATOM   7362  O  O     . CYS B 2 32   ? 147.887 141.019 152.051 1.00 26.39  ? 47   CYS B O     1 
ATOM   7363  C  CB    . CYS B 2 32   ? 148.044 140.365 149.041 1.00 26.39  ? 47   CYS B CB    1 
ATOM   7364  S  SG    . CYS B 2 32   ? 147.200 140.561 147.463 1.00 26.39  ? 47   CYS B SG    1 
ATOM   7365  N  N     . ARG B 2 33   ? 150.012 141.527 151.512 1.00 29.42  ? 48   ARG B N     1 
ATOM   7366  C  CA    . ARG B 2 33   ? 150.464 141.432 152.894 1.00 29.42  ? 48   ARG B CA    1 
ATOM   7367  C  C     . ARG B 2 33   ? 150.245 142.743 153.635 1.00 29.42  ? 48   ARG B C     1 
ATOM   7368  O  O     . ARG B 2 33   ? 149.894 142.739 154.819 1.00 29.42  ? 48   ARG B O     1 
ATOM   7369  C  CB    . ARG B 2 33   ? 151.941 141.038 152.939 1.00 29.42  ? 48   ARG B CB    1 
ATOM   7370  C  CG    . ARG B 2 33   ? 152.474 140.763 154.336 1.00 29.42  ? 48   ARG B CG    1 
ATOM   7371  C  CD    . ARG B 2 33   ? 151.951 139.441 154.878 1.00 29.42  ? 48   ARG B CD    1 
ATOM   7372  N  NE    . ARG B 2 33   ? 152.454 139.165 156.218 1.00 29.42  ? 48   ARG B NE    1 
ATOM   7373  C  CZ    . ARG B 2 33   ? 151.853 139.543 157.337 1.00 29.42  ? 48   ARG B CZ    1 
ATOM   7374  N  NH1   . ARG B 2 33   ? 150.707 140.204 157.318 1.00 29.42  ? 48   ARG B NH1   1 
ATOM   7375  N  NH2   . ARG B 2 33   ? 152.416 139.252 158.506 1.00 29.42  ? 48   ARG B NH2   1 
ATOM   7376  N  N     . ARG B 2 34   ? 150.449 143.873 152.954 1.00 24.82  ? 49   ARG B N     1 
ATOM   7377  C  CA    . ARG B 2 34   ? 150.247 145.170 153.589 1.00 24.82  ? 49   ARG B CA    1 
ATOM   7378  C  C     . ARG B 2 34   ? 148.770 145.426 153.865 1.00 24.82  ? 49   ARG B C     1 
ATOM   7379  O  O     . ARG B 2 34   ? 148.400 145.856 154.964 1.00 24.82  ? 49   ARG B O     1 
ATOM   7380  C  CB    . ARG B 2 34   ? 150.833 146.278 152.719 1.00 24.82  ? 49   ARG B CB    1 
ATOM   7381  C  CG    . ARG B 2 34   ? 150.615 147.669 153.282 1.00 24.82  ? 49   ARG B CG    1 
ATOM   7382  C  CD    . ARG B 2 34   ? 151.333 148.736 152.474 1.00 24.82  ? 49   ARG B CD    1 
ATOM   7383  N  NE    . ARG B 2 34   ? 150.916 148.749 151.078 1.00 24.82  ? 49   ARG B NE    1 
ATOM   7384  C  CZ    . ARG B 2 34   ? 151.621 148.232 150.083 1.00 24.82  ? 49   ARG B CZ    1 
ATOM   7385  N  NH1   . ARG B 2 34   ? 152.792 147.653 150.294 1.00 24.82  ? 49   ARG B NH1   1 
ATOM   7386  N  NH2   . ARG B 2 34   ? 151.142 148.296 148.844 1.00 24.82  ? 49   ARG B NH2   1 
ATOM   7387  N  N     . ARG B 2 35   ? 147.910 145.166 152.879 1.00 21.78  ? 50   ARG B N     1 
ATOM   7388  C  CA    . ARG B 2 35   ? 146.478 145.399 153.008 1.00 21.78  ? 50   ARG B CA    1 
ATOM   7389  C  C     . ARG B 2 35   ? 145.745 144.205 153.591 1.00 21.78  ? 50   ARG B C     1 
ATOM   7390  O  O     . ARG B 2 35   ? 144.533 144.074 153.390 1.00 21.78  ? 50   ARG B O     1 
ATOM   7391  C  CB    . ARG B 2 35   ? 145.874 145.768 151.654 1.00 21.78  ? 50   ARG B CB    1 
ATOM   7392  C  CG    . ARG B 2 35   ? 146.439 147.037 151.064 1.00 21.78  ? 50   ARG B CG    1 
ATOM   7393  C  CD    . ARG B 2 35   ? 146.393 148.166 152.068 1.00 21.78  ? 50   ARG B CD    1 
ATOM   7394  N  NE    . ARG B 2 35   ? 146.968 149.388 151.524 1.00 21.78  ? 50   ARG B NE    1 
ATOM   7395  C  CZ    . ARG B 2 35   ? 147.206 150.481 152.234 1.00 21.78  ? 50   ARG B CZ    1 
ATOM   7396  N  NH1   . ARG B 2 35   ? 146.947 150.533 153.529 1.00 21.78  ? 50   ARG B NH1   1 
ATOM   7397  N  NH2   . ARG B 2 35   ? 147.718 151.548 151.629 1.00 21.78  ? 50   ARG B NH2   1 
ATOM   7398  N  N     . HIS B 2 36   ? 146.456 143.329 154.292 1.00 23.98  ? 51   HIS B N     1 
ATOM   7399  C  CA    . HIS B 2 36   ? 145.868 142.271 155.104 1.00 23.98  ? 51   HIS B CA    1 
ATOM   7400  C  C     . HIS B 2 36   ? 145.042 141.284 154.292 1.00 23.98  ? 51   HIS B C     1 
ATOM   7401  O  O     . HIS B 2 36   ? 144.156 140.621 154.837 1.00 23.98  ? 51   HIS B O     1 
ATOM   7402  C  CB    . HIS B 2 36   ? 145.033 142.863 156.242 1.00 23.98  ? 51   HIS B CB    1 
ATOM   7403  C  CG    . HIS B 2 36   ? 145.834 143.683 157.202 1.00 23.98  ? 51   HIS B CG    1 
ATOM   7404  N  ND1   . HIS B 2 36   ? 146.272 144.956 156.909 1.00 23.98  ? 51   HIS B ND1   1 
ATOM   7405  C  CD2   . HIS B 2 36   ? 146.298 143.401 158.442 1.00 23.98  ? 51   HIS B CD2   1 
ATOM   7406  C  CE1   . HIS B 2 36   ? 146.960 145.430 157.933 1.00 23.98  ? 51   HIS B CE1   1 
ATOM   7407  N  NE2   . HIS B 2 36   ? 146.990 144.505 158.876 1.00 23.98  ? 51   HIS B NE2   1 
ATOM   7408  N  N     . PHE B 2 37   ? 145.308 141.172 152.991 1.00 19.75  ? 52   PHE B N     1 
ATOM   7409  C  CA    . PHE B 2 37   ? 144.858 139.991 152.267 1.00 19.75  ? 52   PHE B CA    1 
ATOM   7410  C  C     . PHE B 2 37   ? 145.706 138.782 152.633 1.00 19.75  ? 52   PHE B C     1 
ATOM   7411  O  O     . PHE B 2 37   ? 145.226 137.644 152.578 1.00 19.75  ? 52   PHE B O     1 
ATOM   7412  C  CB    . PHE B 2 37   ? 144.908 140.231 150.758 1.00 19.75  ? 52   PHE B CB    1 
ATOM   7413  C  CG    . PHE B 2 37   ? 143.769 141.054 150.230 1.00 19.75  ? 52   PHE B CG    1 
ATOM   7414  C  CD1   . PHE B 2 37   ? 142.513 140.497 150.071 1.00 19.75  ? 52   PHE B CD1   1 
ATOM   7415  C  CD2   . PHE B 2 37   ? 143.959 142.376 149.871 1.00 19.75  ? 52   PHE B CD2   1 
ATOM   7416  C  CE1   . PHE B 2 37   ? 141.471 141.245 149.582 1.00 19.75  ? 52   PHE B CE1   1 
ATOM   7417  C  CE2   . PHE B 2 37   ? 142.919 143.125 149.381 1.00 19.75  ? 52   PHE B CE2   1 
ATOM   7418  C  CZ    . PHE B 2 37   ? 141.674 142.559 149.237 1.00 19.75  ? 52   PHE B CZ    1 
ATOM   7419  N  N     . PHE B 2 38   ? 146.969 139.033 152.984 1.00 25.92  ? 53   PHE B N     1 
ATOM   7420  C  CA    . PHE B 2 38   ? 147.901 137.958 153.330 1.00 25.92  ? 53   PHE B CA    1 
ATOM   7421  C  C     . PHE B 2 38   ? 148.592 138.150 154.675 1.00 25.92  ? 53   PHE B C     1 
ATOM   7422  O  O     . PHE B 2 38   ? 149.043 139.249 154.984 1.00 25.92  ? 53   PHE B O     1 
ATOM   7423  C  CB    . PHE B 2 38   ? 148.963 137.834 152.247 1.00 25.92  ? 53   PHE B CB    1 
ATOM   7424  C  CG    . PHE B 2 38   ? 148.517 137.054 151.056 1.00 25.92  ? 53   PHE B CG    1 
ATOM   7425  C  CD1   . PHE B 2 38   ? 147.580 136.050 151.189 1.00 25.92  ? 53   PHE B CD1   1 
ATOM   7426  C  CD2   . PHE B 2 38   ? 149.050 137.311 149.808 1.00 25.92  ? 53   PHE B CD2   1 
ATOM   7427  C  CE1   . PHE B 2 38   ? 147.167 135.325 150.093 1.00 25.92  ? 53   PHE B CE1   1 
ATOM   7428  C  CE2   . PHE B 2 38   ? 148.642 136.590 148.706 1.00 25.92  ? 53   PHE B CE2   1 
ATOM   7429  C  CZ    . PHE B 2 38   ? 147.699 135.594 148.849 1.00 25.92  ? 53   PHE B CZ    1 
ATOM   7430  N  N     . SER B 2 39   ? 148.689 137.090 155.463 1.00 30.55  ? 54   SER B N     1 
ATOM   7431  C  CA    . SER B 2 39   ? 149.313 137.121 156.774 1.00 30.55  ? 54   SER B CA    1 
ATOM   7432  C  C     . SER B 2 39   ? 150.502 136.174 156.789 1.00 30.55  ? 54   SER B C     1 
ATOM   7433  O  O     . SER B 2 39   ? 150.590 135.240 155.989 1.00 30.55  ? 54   SER B O     1 
ATOM   7434  C  CB    . SER B 2 39   ? 148.330 136.726 157.882 1.00 30.55  ? 54   SER B CB    1 
ATOM   7435  O  OG    . SER B 2 39   ? 148.057 135.337 157.839 1.00 30.55  ? 54   SER B OG    1 
ATOM   7436  N  N     . GLY B 2 40   ? 151.422 136.427 157.714 1.00 40.21  ? 55   GLY B N     1 
ATOM   7437  C  CA    . GLY B 2 40   ? 152.572 135.562 157.877 1.00 40.21  ? 55   GLY B CA    1 
ATOM   7438  C  C     . GLY B 2 40   ? 153.896 136.273 157.705 1.00 40.21  ? 55   GLY B C     1 
ATOM   7439  O  O     . GLY B 2 40   ? 153.960 137.368 157.139 1.00 40.21  ? 55   GLY B O     1 
ATOM   7440  N  N     . THR B 2 41   ? 154.963 135.651 158.195 1.00 50.98  ? 56   THR B N     1 
ATOM   7441  C  CA    . THR B 2 41   ? 156.289 136.221 158.072 1.00 50.98  ? 56   THR B CA    1 
ATOM   7442  C  C     . THR B 2 41   ? 156.747 136.180 156.617 1.00 50.98  ? 56   THR B C     1 
ATOM   7443  O  O     . THR B 2 41   ? 156.253 135.375 155.824 1.00 50.98  ? 56   THR B O     1 
ATOM   7444  C  CB    . THR B 2 41   ? 157.270 135.461 158.959 1.00 50.98  ? 56   THR B CB    1 
ATOM   7445  O  OG1   . THR B 2 41   ? 157.206 134.064 158.650 1.00 50.98  ? 56   THR B OG1   1 
ATOM   7446  C  CG2   . THR B 2 41   ? 156.925 135.665 160.425 1.00 50.98  ? 56   THR B CG2   1 
ATOM   7447  N  N     . PRO B 2 42   ? 157.687 137.052 156.238 1.00 58.58  ? 57   PRO B N     1 
ATOM   7448  C  CA    . PRO B 2 42   ? 158.186 137.022 154.853 1.00 58.58  ? 57   PRO B CA    1 
ATOM   7449  C  C     . PRO B 2 42   ? 158.791 135.688 154.458 1.00 58.58  ? 57   PRO B C     1 
ATOM   7450  O  O     . PRO B 2 42   ? 158.841 135.372 153.263 1.00 58.58  ? 57   PRO B O     1 
ATOM   7451  C  CB    . PRO B 2 42   ? 159.233 138.145 154.838 1.00 58.58  ? 57   PRO B CB    1 
ATOM   7452  C  CG    . PRO B 2 42   ? 158.791 139.076 155.909 1.00 58.58  ? 57   PRO B CG    1 
ATOM   7453  C  CD    . PRO B 2 42   ? 158.209 138.208 156.986 1.00 58.58  ? 57   PRO B CD    1 
ATOM   7454  N  N     . GLN B 2 43   ? 159.258 134.895 155.425 1.00 61.04  ? 58   GLN B N     1 
ATOM   7455  C  CA    . GLN B 2 43   ? 159.684 133.534 155.126 1.00 61.04  ? 58   GLN B CA    1 
ATOM   7456  C  C     . GLN B 2 43   ? 158.512 132.644 154.739 1.00 61.04  ? 58   GLN B C     1 
ATOM   7457  O  O     . GLN B 2 43   ? 158.718 131.617 154.084 1.00 61.04  ? 58   GLN B O     1 
ATOM   7458  C  CB    . GLN B 2 43   ? 160.423 132.928 156.322 1.00 61.04  ? 58   GLN B CB    1 
ATOM   7459  C  CG    . GLN B 2 43   ? 161.741 133.608 156.662 1.00 61.04  ? 58   GLN B CG    1 
ATOM   7460  C  CD    . GLN B 2 43   ? 161.555 134.920 157.399 1.00 61.04  ? 58   GLN B CD    1 
ATOM   7461  O  OE1   . GLN B 2 43   ? 160.610 135.083 158.170 1.00 61.04  ? 58   GLN B OE1   1 
ATOM   7462  N  NE2   . GLN B 2 43   ? 162.456 135.865 157.161 1.00 61.04  ? 58   GLN B NE2   1 
ATOM   7463  N  N     . GLN B 2 44   ? 157.295 133.010 155.133 1.00 48.30  ? 59   GLN B N     1 
ATOM   7464  C  CA    . GLN B 2 44   ? 156.094 132.285 154.749 1.00 48.30  ? 59   GLN B CA    1 
ATOM   7465  C  C     . GLN B 2 44   ? 155.433 132.856 153.503 1.00 48.30  ? 59   GLN B C     1 
ATOM   7466  O  O     . GLN B 2 44   ? 154.445 132.287 153.027 1.00 48.30  ? 59   GLN B O     1 
ATOM   7467  C  CB    . GLN B 2 44   ? 155.090 132.281 155.905 1.00 48.30  ? 59   GLN B CB    1 
ATOM   7468  C  CG    . GLN B 2 44   ? 155.567 131.545 157.143 1.00 48.30  ? 59   GLN B CG    1 
ATOM   7469  C  CD    . GLN B 2 44   ? 154.561 131.603 158.274 1.00 48.30  ? 59   GLN B CD    1 
ATOM   7470  O  OE1   . GLN B 2 44   ? 153.643 132.422 158.262 1.00 48.30  ? 59   GLN B OE1   1 
ATOM   7471  N  NE2   . GLN B 2 44   ? 154.727 130.728 159.259 1.00 48.30  ? 59   GLN B NE2   1 
ATOM   7472  N  N     . LEU B 2 45   ? 155.948 133.960 152.967 1.00 51.00  ? 60   LEU B N     1 
ATOM   7473  C  CA    . LEU B 2 45   ? 155.423 134.554 151.745 1.00 51.00  ? 60   LEU B CA    1 
ATOM   7474  C  C     . LEU B 2 45   ? 156.082 133.998 150.492 1.00 51.00  ? 60   LEU B C     1 
ATOM   7475  O  O     . LEU B 2 45   ? 155.792 134.477 149.392 1.00 51.00  ? 60   LEU B O     1 
ATOM   7476  C  CB    . LEU B 2 45   ? 155.586 136.077 151.778 1.00 51.00  ? 60   LEU B CB    1 
ATOM   7477  C  CG    . LEU B 2 45   ? 154.673 136.837 152.740 1.00 51.00  ? 60   LEU B CG    1 
ATOM   7478  C  CD1   . LEU B 2 45   ? 154.873 138.336 152.593 1.00 51.00  ? 60   LEU B CD1   1 
ATOM   7479  C  CD2   . LEU B 2 45   ? 153.219 136.460 152.506 1.00 51.00  ? 60   LEU B CD2   1 
ATOM   7480  N  N     . SER B 2 46   ? 156.967 133.016 150.633 1.00 49.02  ? 61   SER B N     1 
ATOM   7481  C  CA    . SER B 2 46   ? 157.579 132.387 149.477 1.00 49.02  ? 61   SER B CA    1 
ATOM   7482  C  C     . SER B 2 46   ? 156.525 131.645 148.661 1.00 49.02  ? 61   SER B C     1 
ATOM   7483  O  O     . SER B 2 46   ? 155.468 131.256 149.165 1.00 49.02  ? 61   SER B O     1 
ATOM   7484  C  CB    . SER B 2 46   ? 158.684 131.425 149.910 1.00 49.02  ? 61   SER B CB    1 
ATOM   7485  O  OG    . SER B 2 46   ? 159.663 132.094 150.685 1.00 49.02  ? 61   SER B OG    1 
ATOM   7486  N  N     . THR B 2 47   ? 156.828 131.462 147.374 1.00 42.78  ? 62   THR B N     1 
ATOM   7487  C  CA    . THR B 2 47   ? 155.875 130.833 146.467 1.00 42.78  ? 62   THR B CA    1 
ATOM   7488  C  C     . THR B 2 47   ? 155.509 129.427 146.930 1.00 42.78  ? 62   THR B C     1 
ATOM   7489  O  O     . THR B 2 47   ? 154.329 129.061 146.953 1.00 42.78  ? 62   THR B O     1 
ATOM   7490  C  CB    . THR B 2 47   ? 156.450 130.801 145.052 1.00 42.78  ? 62   THR B CB    1 
ATOM   7491  O  OG1   . THR B 2 47   ? 156.668 132.141 144.597 1.00 42.78  ? 62   THR B OG1   1 
ATOM   7492  C  CG2   . THR B 2 47   ? 155.498 130.099 144.105 1.00 42.78  ? 62   THR B CG2   1 
ATOM   7493  N  N     . ALA B 2 48   ? 156.508 128.630 147.320 1.00 40.38  ? 63   ALA B N     1 
ATOM   7494  C  CA    . ALA B 2 48   ? 156.235 127.271 147.775 1.00 40.38  ? 63   ALA B CA    1 
ATOM   7495  C  C     . ALA B 2 48   ? 155.410 127.272 149.055 1.00 40.38  ? 63   ALA B C     1 
ATOM   7496  O  O     . ALA B 2 48   ? 154.521 126.431 149.231 1.00 40.38  ? 63   ALA B O     1 
ATOM   7497  C  CB    . ALA B 2 48   ? 157.545 126.512 147.979 1.00 40.38  ? 63   ALA B CB    1 
ATOM   7498  N  N     . ALA B 2 49   ? 155.693 128.207 149.965 1.00 43.08  ? 64   ALA B N     1 
ATOM   7499  C  CA    . ALA B 2 49   ? 154.909 128.303 151.192 1.00 43.08  ? 64   ALA B CA    1 
ATOM   7500  C  C     . ALA B 2 49   ? 153.462 128.671 150.893 1.00 43.08  ? 64   ALA B C     1 
ATOM   7501  O  O     . ALA B 2 49   ? 152.535 128.117 151.497 1.00 43.08  ? 64   ALA B O     1 
ATOM   7502  C  CB    . ALA B 2 49   ? 155.538 129.322 152.139 1.00 43.08  ? 64   ALA B CB    1 
ATOM   7503  N  N     . LEU B 2 50   ? 153.248 129.608 149.966 1.00 38.63  ? 65   LEU B N     1 
ATOM   7504  C  CA    . LEU B 2 50   ? 151.888 129.975 149.587 1.00 38.63  ? 65   LEU B CA    1 
ATOM   7505  C  C     . LEU B 2 50   ? 151.157 128.804 148.947 1.00 38.63  ? 65   LEU B C     1 
ATOM   7506  O  O     . LEU B 2 50   ? 149.984 128.556 149.246 1.00 38.63  ? 65   LEU B O     1 
ATOM   7507  C  CB    . LEU B 2 50   ? 151.910 131.172 148.637 1.00 38.63  ? 65   LEU B CB    1 
ATOM   7508  C  CG    . LEU B 2 50   ? 152.285 132.521 149.246 1.00 38.63  ? 65   LEU B CG    1 
ATOM   7509  C  CD1   . LEU B 2 50   ? 152.313 133.603 148.180 1.00 38.63  ? 65   LEU B CD1   1 
ATOM   7510  C  CD2   . LEU B 2 50   ? 151.312 132.881 150.352 1.00 38.63  ? 65   LEU B CD2   1 
ATOM   7511  N  N     . LEU B 2 51   ? 151.834 128.068 148.069 1.00 38.36  ? 66   LEU B N     1 
ATOM   7512  C  CA    . LEU B 2 51   ? 151.198 126.989 147.323 1.00 38.36  ? 66   LEU B CA    1 
ATOM   7513  C  C     . LEU B 2 51   ? 151.158 125.671 148.085 1.00 38.36  ? 66   LEU B C     1 
ATOM   7514  O  O     . LEU B 2 51   ? 150.600 124.698 147.568 1.00 38.36  ? 66   LEU B O     1 
ATOM   7515  C  CB    . LEU B 2 51   ? 151.913 126.782 145.984 1.00 38.36  ? 66   LEU B CB    1 
ATOM   7516  C  CG    . LEU B 2 51   ? 152.087 128.002 145.075 1.00 38.36  ? 66   LEU B CG    1 
ATOM   7517  C  CD1   . LEU B 2 51   ? 152.711 127.594 143.752 1.00 38.36  ? 66   LEU B CD1   1 
ATOM   7518  C  CD2   . LEU B 2 51   ? 150.770 128.724 144.854 1.00 38.36  ? 66   LEU B CD2   1 
ATOM   7519  N  N     . SER B 2 52   ? 151.737 125.604 149.283 1.00 42.24  ? 67   SER B N     1 
ATOM   7520  C  CA    . SER B 2 52   ? 151.716 124.387 150.085 1.00 42.24  ? 67   SER B CA    1 
ATOM   7521  C  C     . SER B 2 52   ? 150.605 124.376 151.126 1.00 42.24  ? 67   SER B C     1 
ATOM   7522  O  O     . SER B 2 52   ? 149.968 123.339 151.334 1.00 42.24  ? 67   SER B O     1 
ATOM   7523  C  CB    . SER B 2 52   ? 153.065 124.189 150.780 1.00 42.24  ? 67   SER B CB    1 
ATOM   7524  O  OG    . SER B 2 52   ? 153.398 125.315 151.571 1.00 42.24  ? 67   SER B OG    1 
ATOM   7525  N  N     . GLY B 2 53   ? 150.359 125.504 151.786 1.00 46.27  ? 68   GLY B N     1 
ATOM   7526  C  CA    . GLY B 2 53   ? 149.290 125.583 152.758 1.00 46.27  ? 68   GLY B CA    1 
ATOM   7527  C  C     . GLY B 2 53   ? 149.672 125.194 154.165 1.00 46.27  ? 68   GLY B C     1 
ATOM   7528  O  O     . GLY B 2 53   ? 148.803 124.774 154.937 1.00 46.27  ? 68   GLY B O     1 
ATOM   7529  N  N     . CYS B 2 54   ? 150.946 125.315 154.526 1.00 49.43  ? 69   CYS B N     1 
ATOM   7530  C  CA    . CYS B 2 54   ? 151.426 124.921 155.843 1.00 49.43  ? 69   CYS B CA    1 
ATOM   7531  C  C     . CYS B 2 54   ? 151.331 126.038 156.875 1.00 49.43  ? 69   CYS B C     1 
ATOM   7532  O  O     . CYS B 2 54   ? 151.648 125.804 158.045 1.00 49.43  ? 69   CYS B O     1 
ATOM   7533  C  CB    . CYS B 2 54   ? 152.874 124.433 155.746 1.00 49.43  ? 69   CYS B CB    1 
ATOM   7534  S  SG    . CYS B 2 54   ? 154.031 125.663 155.109 1.00 49.43  ? 69   CYS B SG    1 
ATOM   7535  N  N     . HIS B 2 55   ? 150.912 127.238 156.479 1.00 42.71  ? 70   HIS B N     1 
ATOM   7536  C  CA    . HIS B 2 55   ? 150.802 128.357 157.402 1.00 42.71  ? 70   HIS B CA    1 
ATOM   7537  C  C     . HIS B 2 55   ? 149.552 129.160 157.075 1.00 42.71  ? 70   HIS B C     1 
ATOM   7538  O  O     . HIS B 2 55   ? 149.030 129.108 155.959 1.00 42.71  ? 70   HIS B O     1 
ATOM   7539  C  CB    . HIS B 2 55   ? 152.045 129.259 157.354 1.00 42.71  ? 70   HIS B CB    1 
ATOM   7540  C  CG    . HIS B 2 55   ? 152.092 130.167 156.164 1.00 42.71  ? 70   HIS B CG    1 
ATOM   7541  N  ND1   . HIS B 2 55   ? 151.575 131.444 156.182 1.00 42.71  ? 70   HIS B ND1   1 
ATOM   7542  C  CD2   . HIS B 2 55   ? 152.601 129.985 154.923 1.00 42.71  ? 70   HIS B CD2   1 
ATOM   7543  C  CE1   . HIS B 2 55   ? 151.761 132.009 155.003 1.00 42.71  ? 70   HIS B CE1   1 
ATOM   7544  N  NE2   . HIS B 2 55   ? 152.382 131.145 154.220 1.00 42.71  ? 70   HIS B NE2   1 
ATOM   7545  N  N     . ALA B 2 56   ? 149.074 129.904 158.069 1.00 35.77  ? 71   ALA B N     1 
ATOM   7546  C  CA    . ALA B 2 56   ? 147.902 130.759 157.894 1.00 35.77  ? 71   ALA B CA    1 
ATOM   7547  C  C     . ALA B 2 56   ? 148.289 131.927 156.999 1.00 35.77  ? 71   ALA B C     1 
ATOM   7548  O  O     . ALA B 2 56   ? 148.878 132.909 157.455 1.00 35.77  ? 71   ALA B O     1 
ATOM   7549  C  CB    . ALA B 2 56   ? 147.384 131.239 159.244 1.00 35.77  ? 71   ALA B CB    1 
ATOM   7550  N  N     . ARG B 2 57   ? 147.958 131.822 155.714 1.00 30.89  ? 72   ARG B N     1 
ATOM   7551  C  CA    . ARG B 2 57   ? 148.375 132.814 154.734 1.00 30.89  ? 72   ARG B CA    1 
ATOM   7552  C  C     . ARG B 2 57   ? 147.407 133.978 154.604 1.00 30.89  ? 72   ARG B C     1 
ATOM   7553  O  O     . ARG B 2 57   ? 147.846 135.112 154.393 1.00 30.89  ? 72   ARG B O     1 
ATOM   7554  C  CB    . ARG B 2 57   ? 148.552 132.152 153.367 1.00 30.89  ? 72   ARG B CB    1 
ATOM   7555  C  CG    . ARG B 2 57   ? 147.523 131.080 153.088 1.00 30.89  ? 72   ARG B CG    1 
ATOM   7556  C  CD    . ARG B 2 57   ? 147.855 130.294 151.837 1.00 30.89  ? 72   ARG B CD    1 
ATOM   7557  N  NE    . ARG B 2 57   ? 147.191 128.997 151.847 1.00 30.89  ? 72   ARG B NE    1 
ATOM   7558  C  CZ    . ARG B 2 57   ? 147.176 128.153 150.825 1.00 30.89  ? 72   ARG B CZ    1 
ATOM   7559  N  NH1   . ARG B 2 57   ? 147.761 128.448 149.676 1.00 30.89  ? 72   ARG B NH1   1 
ATOM   7560  N  NH2   . ARG B 2 57   ? 146.554 126.986 150.958 1.00 30.89  ? 72   ARG B NH2   1 
ATOM   7561  N  N     . PHE B 2 58   ? 146.107 133.732 154.731 1.00 22.00  ? 73   PHE B N     1 
ATOM   7562  C  CA    . PHE B 2 58   ? 145.095 134.735 154.428 1.00 22.00  ? 73   PHE B CA    1 
ATOM   7563  C  C     . PHE B 2 58   ? 144.851 135.623 155.639 1.00 22.00  ? 73   PHE B C     1 
ATOM   7564  O  O     . PHE B 2 58   ? 144.488 135.132 156.713 1.00 22.00  ? 73   PHE B O     1 
ATOM   7565  C  CB    . PHE B 2 58   ? 143.794 134.066 153.995 1.00 22.00  ? 73   PHE B CB    1 
ATOM   7566  C  CG    . PHE B 2 58   ? 143.865 133.423 152.647 1.00 22.00  ? 73   PHE B CG    1 
ATOM   7567  C  CD1   . PHE B 2 58   ? 144.547 134.033 151.608 1.00 22.00  ? 73   PHE B CD1   1 
ATOM   7568  C  CD2   . PHE B 2 58   ? 143.253 132.207 152.418 1.00 22.00  ? 73   PHE B CD2   1 
ATOM   7569  C  CE1   . PHE B 2 58   ? 144.612 133.441 150.369 1.00 22.00  ? 73   PHE B CE1   1 
ATOM   7570  C  CE2   . PHE B 2 58   ? 143.316 131.612 151.182 1.00 22.00  ? 73   PHE B CE2   1 
ATOM   7571  C  CZ    . PHE B 2 58   ? 143.997 132.230 150.156 1.00 22.00  ? 73   PHE B CZ    1 
ATOM   7572  N  N     . GLY B 2 59   ? 145.046 136.927 155.463 1.00 19.23  ? 74   GLY B N     1 
ATOM   7573  C  CA    . GLY B 2 59   ? 144.682 137.896 156.466 1.00 19.23  ? 74   GLY B CA    1 
ATOM   7574  C  C     . GLY B 2 59   ? 143.178 138.066 156.545 1.00 19.23  ? 74   GLY B C     1 
ATOM   7575  O  O     . GLY B 2 59   ? 142.416 137.290 155.962 1.00 19.23  ? 74   GLY B O     1 
ATOM   7576  N  N     . PRO B 2 60   ? 142.719 139.087 157.274 1.00 16.49  ? 75   PRO B N     1 
ATOM   7577  C  CA    . PRO B 2 60   ? 141.263 139.291 157.396 1.00 16.49  ? 75   PRO B CA    1 
ATOM   7578  C  C     . PRO B 2 60   ? 140.569 139.492 156.062 1.00 16.49  ? 75   PRO B C     1 
ATOM   7579  O  O     . PRO B 2 60   ? 139.605 138.779 155.749 1.00 16.49  ? 75   PRO B O     1 
ATOM   7580  C  CB    . PRO B 2 60   ? 141.164 140.536 158.289 1.00 16.49  ? 75   PRO B CB    1 
ATOM   7581  C  CG    . PRO B 2 60   ? 142.462 140.598 159.011 1.00 16.49  ? 75   PRO B CG    1 
ATOM   7582  C  CD    . PRO B 2 60   ? 143.485 140.070 158.056 1.00 16.49  ? 75   PRO B CD    1 
ATOM   7583  N  N     . LEU B 2 61   ? 141.031 140.455 155.262 1.00 16.02  ? 76   LEU B N     1 
ATOM   7584  C  CA    . LEU B 2 61   ? 140.413 140.694 153.963 1.00 16.02  ? 76   LEU B CA    1 
ATOM   7585  C  C     . LEU B 2 61   ? 140.553 139.480 153.060 1.00 16.02  ? 76   LEU B C     1 
ATOM   7586  O  O     . LEU B 2 61   ? 139.658 139.184 152.264 1.00 16.02  ? 76   LEU B O     1 
ATOM   7587  C  CB    . LEU B 2 61   ? 141.025 141.929 153.303 1.00 16.02  ? 76   LEU B CB    1 
ATOM   7588  C  CG    . LEU B 2 61   ? 140.524 143.305 153.745 1.00 16.02  ? 76   LEU B CG    1 
ATOM   7589  C  CD1   . LEU B 2 61   ? 140.957 143.637 155.163 1.00 16.02  ? 76   LEU B CD1   1 
ATOM   7590  C  CD2   . LEU B 2 61   ? 141.002 144.371 152.781 1.00 16.02  ? 76   LEU B CD2   1 
ATOM   7591  N  N     . GLY B 2 62   ? 141.675 138.770 153.158 1.00 17.44  ? 77   GLY B N     1 
ATOM   7592  C  CA    . GLY B 2 62   ? 141.823 137.545 152.393 1.00 17.44  ? 77   GLY B CA    1 
ATOM   7593  C  C     . GLY B 2 62   ? 140.805 136.495 152.789 1.00 17.44  ? 77   GLY B C     1 
ATOM   7594  O  O     . GLY B 2 62   ? 140.247 135.806 151.934 1.00 17.44  ? 77   GLY B O     1 
ATOM   7595  N  N     . VAL B 2 63   ? 140.540 136.366 154.090 1.00 17.38  ? 78   VAL B N     1 
ATOM   7596  C  CA    . VAL B 2 63   ? 139.532 135.415 154.543 1.00 17.38  ? 78   VAL B CA    1 
ATOM   7597  C  C     . VAL B 2 63   ? 138.148 135.838 154.068 1.00 17.38  ? 78   VAL B C     1 
ATOM   7598  O  O     . VAL B 2 63   ? 137.328 134.998 153.687 1.00 17.38  ? 78   VAL B O     1 
ATOM   7599  C  CB    . VAL B 2 63   ? 139.584 135.264 156.074 1.00 17.38  ? 78   VAL B CB    1 
ATOM   7600  C  CG1   . VAL B 2 63   ? 138.421 134.422 156.560 1.00 17.38  ? 78   VAL B CG1   1 
ATOM   7601  C  CG2   . VAL B 2 63   ? 140.893 134.629 156.485 1.00 17.38  ? 78   VAL B CG2   1 
ATOM   7602  N  N     . GLU B 2 64   ? 137.865 137.143 154.073 1.00 15.24  ? 79   GLU B N     1 
ATOM   7603  C  CA    . GLU B 2 64   ? 136.566 137.605 153.594 1.00 15.24  ? 79   GLU B CA    1 
ATOM   7604  C  C     . GLU B 2 64   ? 136.405 137.362 152.098 1.00 15.24  ? 79   GLU B C     1 
ATOM   7605  O  O     . GLU B 2 64   ? 135.327 136.967 151.641 1.00 15.24  ? 79   GLU B O     1 
ATOM   7606  C  CB    . GLU B 2 64   ? 136.374 139.082 153.922 1.00 15.24  ? 79   GLU B CB    1 
ATOM   7607  C  CG    . GLU B 2 64   ? 134.966 139.584 153.649 1.00 15.24  ? 79   GLU B CG    1 
ATOM   7608  C  CD    . GLU B 2 64   ? 133.915 138.850 154.462 1.00 15.24  ? 79   GLU B CD    1 
ATOM   7609  O  OE1   . GLU B 2 64   ? 134.225 138.425 155.595 1.00 15.24  ? 79   GLU B OE1   1 
ATOM   7610  O  OE2   . GLU B 2 64   ? 132.780 138.696 153.966 1.00 15.24  ? 79   GLU B OE2   1 
ATOM   7611  N  N     . LEU B 2 65   ? 137.463 137.592 151.318 1.00 17.67  ? 80   LEU B N     1 
ATOM   7612  C  CA    . LEU B 2 65   ? 137.410 137.298 149.890 1.00 17.67  ? 80   LEU B CA    1 
ATOM   7613  C  C     . LEU B 2 65   ? 137.246 135.805 149.643 1.00 17.67  ? 80   LEU B C     1 
ATOM   7614  O  O     . LEU B 2 65   ? 136.512 135.395 148.738 1.00 17.67  ? 80   LEU B O     1 
ATOM   7615  C  CB    . LEU B 2 65   ? 138.664 137.831 149.198 1.00 17.67  ? 80   LEU B CB    1 
ATOM   7616  C  CG    . LEU B 2 65   ? 139.207 137.128 147.952 1.00 17.67  ? 80   LEU B CG    1 
ATOM   7617  C  CD1   . LEU B 2 65   ? 138.221 137.132 146.801 1.00 17.67  ? 80   LEU B CD1   1 
ATOM   7618  C  CD2   . LEU B 2 65   ? 140.504 137.780 147.524 1.00 17.67  ? 80   LEU B CD2   1 
ATOM   7619  N  N     . ARG B 2 66   ? 137.920 134.972 150.435 1.00 20.01  ? 81   ARG B N     1 
ATOM   7620  C  CA    . ARG B 2 66   ? 137.748 133.533 150.286 1.00 20.01  ? 81   ARG B CA    1 
ATOM   7621  C  C     . ARG B 2 66   ? 136.340 133.104 150.663 1.00 20.01  ? 81   ARG B C     1 
ATOM   7622  O  O     . ARG B 2 66   ? 135.788 132.184 150.052 1.00 20.01  ? 81   ARG B O     1 
ATOM   7623  C  CB    . ARG B 2 66   ? 138.778 132.794 151.133 1.00 20.01  ? 81   ARG B CB    1 
ATOM   7624  C  CG    . ARG B 2 66   ? 138.849 131.311 150.849 1.00 20.01  ? 81   ARG B CG    1 
ATOM   7625  C  CD    . ARG B 2 66   ? 139.815 130.637 151.795 1.00 20.01  ? 81   ARG B CD    1 
ATOM   7626  N  NE    . ARG B 2 66   ? 139.285 130.556 153.149 1.00 20.01  ? 81   ARG B NE    1 
ATOM   7627  C  CZ    . ARG B 2 66   ? 140.015 130.291 154.222 1.00 20.01  ? 81   ARG B CZ    1 
ATOM   7628  N  NH1   . ARG B 2 66   ? 141.322 130.105 154.138 1.00 20.01  ? 81   ARG B NH1   1 
ATOM   7629  N  NH2   . ARG B 2 66   ? 139.422 130.215 155.409 1.00 20.01  ? 81   ARG B NH2   1 
ATOM   7630  N  N     . LYS B 2 67   ? 135.741 133.766 151.652 1.00 16.96  ? 82   LYS B N     1 
ATOM   7631  C  CA    . LYS B 2 67   ? 134.355 133.490 152.005 1.00 16.96  ? 82   LYS B CA    1 
ATOM   7632  C  C     . LYS B 2 67   ? 133.410 133.912 150.887 1.00 16.96  ? 82   LYS B C     1 
ATOM   7633  O  O     . LYS B 2 67   ? 132.430 133.218 150.603 1.00 16.96  ? 82   LYS B O     1 
ATOM   7634  C  CB    . LYS B 2 67   ? 134.007 134.201 153.311 1.00 16.96  ? 82   LYS B CB    1 
ATOM   7635  C  CG    . LYS B 2 67   ? 132.658 133.833 153.886 1.00 16.96  ? 82   LYS B CG    1 
ATOM   7636  C  CD    . LYS B 2 67   ? 132.438 134.527 155.219 1.00 16.96  ? 82   LYS B CD    1 
ATOM   7637  C  CE    . LYS B 2 67   ? 131.110 134.130 155.833 1.00 16.96  ? 82   LYS B CE    1 
ATOM   7638  N  NZ    . LYS B 2 67   ? 131.040 132.671 156.123 1.00 16.96  ? 82   LYS B NZ    1 
ATOM   7639  N  N     . ASN B 2 68   ? 133.694 135.042 150.236 1.00 17.30  ? 83   ASN B N     1 
ATOM   7640  C  CA    . ASN B 2 68   ? 132.915 135.448 149.068 1.00 17.30  ? 83   ASN B CA    1 
ATOM   7641  C  C     . ASN B 2 68   ? 133.037 134.430 147.943 1.00 17.30  ? 83   ASN B C     1 
ATOM   7642  O  O     . ASN B 2 68   ? 132.046 134.095 147.286 1.00 17.30  ? 83   ASN B O     1 
ATOM   7643  C  CB    . ASN B 2 68   ? 133.367 136.823 148.579 1.00 17.30  ? 83   ASN B CB    1 
ATOM   7644  C  CG    . ASN B 2 68   ? 133.164 137.906 149.611 1.00 17.30  ? 83   ASN B CG    1 
ATOM   7645  O  OD1   . ASN B 2 68   ? 132.423 137.728 150.575 1.00 17.30  ? 83   ASN B OD1   1 
ATOM   7646  N  ND2   . ASN B 2 68   ? 133.818 139.044 149.411 1.00 17.30  ? 83   ASN B ND2   1 
ATOM   7647  N  N     . LEU B 2 69   ? 134.254 133.944 147.694 1.00 14.24  ? 84   LEU B N     1 
ATOM   7648  C  CA    . LEU B 2 69   ? 134.467 132.939 146.657 1.00 14.24  ? 84   LEU B CA    1 
ATOM   7649  C  C     . LEU B 2 69   ? 133.709 131.659 146.972 1.00 14.24  ? 84   LEU B C     1 
ATOM   7650  O  O     . LEU B 2 69   ? 133.080 131.063 146.088 1.00 14.24  ? 84   LEU B O     1 
ATOM   7651  C  CB    . LEU B 2 69   ? 135.961 132.655 146.514 1.00 14.24  ? 84   LEU B CB    1 
ATOM   7652  C  CG    . LEU B 2 69   ? 136.398 131.697 145.410 1.00 14.24  ? 84   LEU B CG    1 
ATOM   7653  C  CD1   . LEU B 2 69   ? 136.038 132.278 144.062 1.00 14.24  ? 84   LEU B CD1   1 
ATOM   7654  C  CD2   . LEU B 2 69   ? 137.889 131.433 145.499 1.00 14.24  ? 84   LEU B CD2   1 
ATOM   7655  N  N     . ALA B 2 70   ? 133.752 131.225 148.232 1.00 14.60  ? 85   ALA B N     1 
ATOM   7656  C  CA    . ALA B 2 70   ? 133.012 130.037 148.636 1.00 14.60  ? 85   ALA B CA    1 
ATOM   7657  C  C     . ALA B 2 70   ? 131.513 130.258 148.517 1.00 14.60  ? 85   ALA B C     1 
ATOM   7658  O  O     . ALA B 2 70   ? 130.773 129.338 148.162 1.00 14.60  ? 85   ALA B O     1 
ATOM   7659  C  CB    . ALA B 2 70   ? 133.385 129.647 150.065 1.00 14.60  ? 85   ALA B CB    1 
ATOM   7660  N  N     . SER B 2 71   ? 131.044 131.474 148.807 1.00 13.13  ? 86   SER B N     1 
ATOM   7661  C  CA    . SER B 2 71   ? 129.623 131.772 148.668 1.00 13.13  ? 86   SER B CA    1 
ATOM   7662  C  C     . SER B 2 71   ? 129.186 131.729 147.211 1.00 13.13  ? 86   SER B C     1 
ATOM   7663  O  O     . SER B 2 71   ? 128.122 131.187 146.894 1.00 13.13  ? 86   SER B O     1 
ATOM   7664  C  CB    . SER B 2 71   ? 129.306 133.135 149.275 1.00 13.13  ? 86   SER B CB    1 
ATOM   7665  O  OG    . SER B 2 71   ? 127.938 133.452 149.096 1.00 13.13  ? 86   SER B OG    1 
ATOM   7666  N  N     . GLN B 2 72   ? 129.983 132.314 146.315 1.00 15.65  ? 87   GLN B N     1 
ATOM   7667  C  CA    . GLN B 2 72   ? 129.670 132.243 144.892 1.00 15.65  ? 87   GLN B CA    1 
ATOM   7668  C  C     . GLN B 2 72   ? 129.647 130.798 144.417 1.00 15.65  ? 87   GLN B C     1 
ATOM   7669  O  O     . GLN B 2 72   ? 128.725 130.379 143.707 1.00 15.65  ? 87   GLN B O     1 
ATOM   7670  C  CB    . GLN B 2 72   ? 130.683 133.052 144.083 1.00 15.65  ? 87   GLN B CB    1 
ATOM   7671  C  CG    . GLN B 2 72   ? 130.790 134.508 144.478 1.00 15.65  ? 87   GLN B CG    1 
ATOM   7672  C  CD    . GLN B 2 72   ? 129.601 135.324 144.037 1.00 15.65  ? 87   GLN B CD    1 
ATOM   7673  O  OE1   . GLN B 2 72   ? 129.202 136.271 144.712 1.00 15.65  ? 87   GLN B OE1   1 
ATOM   7674  N  NE2   . GLN B 2 72   ? 129.031 134.971 142.893 1.00 15.65  ? 87   GLN B NE2   1 
ATOM   7675  N  N     . TRP B 2 73   ? 130.655 130.018 144.812 1.00 16.83  ? 88   TRP B N     1 
ATOM   7676  C  CA    . TRP B 2 73   ? 130.693 128.605 144.457 1.00 16.83  ? 88   TRP B CA    1 
ATOM   7677  C  C     . TRP B 2 73   ? 129.450 127.888 144.961 1.00 16.83  ? 88   TRP B C     1 
ATOM   7678  O  O     . TRP B 2 73   ? 128.793 127.153 144.215 1.00 16.83  ? 88   TRP B O     1 
ATOM   7679  C  CB    . TRP B 2 73   ? 131.958 127.969 145.036 1.00 16.83  ? 88   TRP B CB    1 
ATOM   7680  C  CG    . TRP B 2 73   ? 132.323 126.632 144.465 1.00 16.83  ? 88   TRP B CG    1 
ATOM   7681  C  CD1   . TRP B 2 73   ? 133.211 126.390 143.464 1.00 16.83  ? 88   TRP B CD1   1 
ATOM   7682  C  CD2   . TRP B 2 73   ? 131.826 125.354 144.878 1.00 16.83  ? 88   TRP B CD2   1 
ATOM   7683  N  NE1   . TRP B 2 73   ? 133.292 125.042 143.216 1.00 16.83  ? 88   TRP B NE1   1 
ATOM   7684  C  CE2   . TRP B 2 73   ? 132.451 124.384 144.073 1.00 16.83  ? 88   TRP B CE2   1 
ATOM   7685  C  CE3   . TRP B 2 73   ? 130.910 124.937 145.847 1.00 16.83  ? 88   TRP B CE3   1 
ATOM   7686  C  CZ2   . TRP B 2 73   ? 132.189 123.025 144.207 1.00 16.83  ? 88   TRP B CZ2   1 
ATOM   7687  C  CZ3   . TRP B 2 73   ? 130.652 123.591 145.977 1.00 16.83  ? 88   TRP B CZ3   1 
ATOM   7688  C  CH2   . TRP B 2 73   ? 131.288 122.650 145.163 1.00 16.83  ? 88   TRP B CH2   1 
ATOM   7689  N  N     . TRP B 2 74   ? 129.092 128.122 146.221 1.00 15.07  ? 89   TRP B N     1 
ATOM   7690  C  CA    . TRP B 2 74   ? 127.985 127.400 146.830 1.00 15.07  ? 89   TRP B CA    1 
ATOM   7691  C  C     . TRP B 2 74   ? 126.665 127.756 146.165 1.00 15.07  ? 89   TRP B C     1 
ATOM   7692  O  O     . TRP B 2 74   ? 125.863 126.871 145.849 1.00 15.07  ? 89   TRP B O     1 
ATOM   7693  C  CB    . TRP B 2 74   ? 127.939 127.696 148.326 1.00 15.07  ? 89   TRP B CB    1 
ATOM   7694  C  CG    . TRP B 2 74   ? 127.050 126.775 149.075 1.00 15.07  ? 89   TRP B CG    1 
ATOM   7695  C  CD1   . TRP B 2 74   ? 125.811 127.052 149.568 1.00 15.07  ? 89   TRP B CD1   1 
ATOM   7696  C  CD2   . TRP B 2 74   ? 127.324 125.413 149.413 1.00 15.07  ? 89   TRP B CD2   1 
ATOM   7697  N  NE1   . TRP B 2 74   ? 125.296 125.947 150.198 1.00 15.07  ? 89   TRP B NE1   1 
ATOM   7698  C  CE2   . TRP B 2 74   ? 126.207 124.926 150.116 1.00 15.07  ? 89   TRP B CE2   1 
ATOM   7699  C  CE3   . TRP B 2 74   ? 128.405 124.559 149.191 1.00 15.07  ? 89   TRP B CE3   1 
ATOM   7700  C  CZ2   . TRP B 2 74   ? 126.142 123.624 150.599 1.00 15.07  ? 89   TRP B CZ2   1 
ATOM   7701  C  CZ3   . TRP B 2 74   ? 128.338 123.270 149.671 1.00 15.07  ? 89   TRP B CZ3   1 
ATOM   7702  C  CH2   . TRP B 2 74   ? 127.215 122.813 150.366 1.00 15.07  ? 89   TRP B CH2   1 
ATOM   7703  N  N     . SER B 2 75   ? 126.422 129.047 145.934 1.00 19.24  ? 90   SER B N     1 
ATOM   7704  C  CA    . SER B 2 75   ? 125.188 129.449 145.269 1.00 19.24  ? 90   SER B CA    1 
ATOM   7705  C  C     . SER B 2 75   ? 125.122 128.879 143.860 1.00 19.24  ? 90   SER B C     1 
ATOM   7706  O  O     . SER B 2 75   ? 124.167 128.177 143.510 1.00 19.24  ? 90   SER B O     1 
ATOM   7707  C  CB    . SER B 2 75   ? 125.080 130.973 145.238 1.00 19.24  ? 90   SER B CB    1 
ATOM   7708  O  OG    . SER B 2 75   ? 126.082 131.535 144.410 1.00 19.24  ? 90   SER B OG    1 
ATOM   7709  N  N     . SER B 2 76   ? 126.165 129.117 143.057 1.00 19.10  ? 91   SER B N     1 
ATOM   7710  C  CA    . SER B 2 76   ? 126.174 128.683 141.666 1.00 19.10  ? 91   SER B CA    1 
ATOM   7711  C  C     . SER B 2 76   ? 126.167 127.170 141.510 1.00 19.10  ? 91   SER B C     1 
ATOM   7712  O  O     . SER B 2 76   ? 125.855 126.680 140.421 1.00 19.10  ? 91   SER B O     1 
ATOM   7713  C  CB    . SER B 2 76   ? 127.395 129.258 140.953 1.00 19.10  ? 91   SER B CB    1 
ATOM   7714  O  OG    . SER B 2 76   ? 127.647 128.560 139.749 1.00 19.10  ? 91   SER B OG    1 
ATOM   7715  N  N     . MET B 2 77   ? 126.511 126.415 142.552 1.00 20.56  ? 92   MET B N     1 
ATOM   7716  C  CA    . MET B 2 77   ? 126.581 124.970 142.417 1.00 20.56  ? 92   MET B CA    1 
ATOM   7717  C  C     . MET B 2 77   ? 125.482 124.210 143.142 1.00 20.56  ? 92   MET B C     1 
ATOM   7718  O  O     . MET B 2 77   ? 125.224 123.061 142.779 1.00 20.56  ? 92   MET B O     1 
ATOM   7719  C  CB    . MET B 2 77   ? 127.941 124.458 142.912 1.00 20.56  ? 92   MET B CB    1 
ATOM   7720  C  CG    . MET B 2 77   ? 129.112 124.909 142.060 1.00 20.56  ? 92   MET B CG    1 
ATOM   7721  S  SD    . MET B 2 77   ? 129.183 124.061 140.478 1.00 20.56  ? 92   MET B SD    1 
ATOM   7722  C  CE    . MET B 2 77   ? 129.406 122.379 141.035 1.00 20.56  ? 92   MET B CE    1 
ATOM   7723  N  N     . VAL B 2 78   ? 124.829 124.800 144.144 1.00 20.56  ? 93   VAL B N     1 
ATOM   7724  C  CA    . VAL B 2 78   ? 123.825 124.066 144.905 1.00 20.56  ? 93   VAL B CA    1 
ATOM   7725  C  C     . VAL B 2 78   ? 122.493 124.809 144.908 1.00 20.56  ? 93   VAL B C     1 
ATOM   7726  O  O     . VAL B 2 78   ? 121.427 124.188 144.989 1.00 20.56  ? 93   VAL B O     1 
ATOM   7727  C  CB    . VAL B 2 78   ? 124.314 123.817 146.344 1.00 20.56  ? 93   VAL B CB    1 
ATOM   7728  C  CG1   . VAL B 2 78   ? 123.309 122.990 147.125 1.00 20.56  ? 93   VAL B CG1   1 
ATOM   7729  C  CG2   . VAL B 2 78   ? 125.673 123.135 146.336 1.00 20.56  ? 93   VAL B CG2   1 
ATOM   7730  N  N     . VAL B 2 79   ? 122.535 126.136 144.796 1.00 24.23  ? 94   VAL B N     1 
ATOM   7731  C  CA    . VAL B 2 79   ? 121.320 126.938 144.865 1.00 24.23  ? 94   VAL B CA    1 
ATOM   7732  C  C     . VAL B 2 79   ? 120.803 127.176 143.454 1.00 24.23  ? 94   VAL B C     1 
ATOM   7733  O  O     . VAL B 2 79   ? 119.668 126.812 143.127 1.00 24.23  ? 94   VAL B O     1 
ATOM   7734  C  CB    . VAL B 2 79   ? 121.571 128.266 145.603 1.00 24.23  ? 94   VAL B CB    1 
ATOM   7735  C  CG1   . VAL B 2 79   ? 120.364 129.174 145.484 1.00 24.23  ? 94   VAL B CG1   1 
ATOM   7736  C  CG2   . VAL B 2 79   ? 121.892 128.000 147.065 1.00 24.23  ? 94   VAL B CG2   1 
ATOM   7737  N  N     . PHE B 2 80   ? 121.637 127.778 142.605 1.00 26.63  ? 95   PHE B N     1 
ATOM   7738  C  CA    . PHE B 2 80   ? 121.277 127.978 141.208 1.00 26.63  ? 95   PHE B CA    1 
ATOM   7739  C  C     . PHE B 2 80   ? 121.289 126.683 140.411 1.00 26.63  ? 95   PHE B C     1 
ATOM   7740  O  O     . PHE B 2 80   ? 120.907 126.694 139.237 1.00 26.63  ? 95   PHE B O     1 
ATOM   7741  C  CB    . PHE B 2 80   ? 122.222 128.990 140.559 1.00 26.63  ? 95   PHE B CB    1 
ATOM   7742  C  CG    . PHE B 2 80   ? 122.097 130.377 141.116 1.00 26.63  ? 95   PHE B CG    1 
ATOM   7743  C  CD1   . PHE B 2 80   ? 120.936 130.777 141.754 1.00 26.63  ? 95   PHE B CD1   1 
ATOM   7744  C  CD2   . PHE B 2 80   ? 123.140 131.281 141.004 1.00 26.63  ? 95   PHE B CD2   1 
ATOM   7745  C  CE1   . PHE B 2 80   ? 120.816 132.049 142.269 1.00 26.63  ? 95   PHE B CE1   1 
ATOM   7746  C  CE2   . PHE B 2 80   ? 123.026 132.556 141.518 1.00 26.63  ? 95   PHE B CE2   1 
ATOM   7747  C  CZ    . PHE B 2 80   ? 121.862 132.940 142.151 1.00 26.63  ? 95   PHE B CZ    1 
ATOM   7748  N  N     . ARG B 2 81   ? 121.719 125.579 141.014 1.00 24.97  ? 96   ARG B N     1 
ATOM   7749  C  CA    . ARG B 2 81   ? 121.847 124.298 140.338 1.00 24.97  ? 96   ARG B CA    1 
ATOM   7750  C  C     . ARG B 2 81   ? 120.952 123.276 141.020 1.00 24.97  ? 96   ARG B C     1 
ATOM   7751  O  O     . ARG B 2 81   ? 120.984 123.137 142.246 1.00 24.97  ? 96   ARG B O     1 
ATOM   7752  C  CB    . ARG B 2 81   ? 123.301 123.824 140.355 1.00 24.97  ? 96   ARG B CB    1 
ATOM   7753  C  CG    . ARG B 2 81   ? 123.538 122.478 139.704 1.00 24.97  ? 96   ARG B CG    1 
ATOM   7754  C  CD    . ARG B 2 81   ? 123.351 122.545 138.204 1.00 24.97  ? 96   ARG B CD    1 
ATOM   7755  N  NE    . ARG B 2 81   ? 123.783 123.830 137.671 1.00 24.97  ? 96   ARG B NE    1 
ATOM   7756  C  CZ    . ARG B 2 81   ? 125.048 124.183 137.493 1.00 24.97  ? 96   ARG B CZ    1 
ATOM   7757  N  NH1   . ARG B 2 81   ? 126.043 123.372 137.809 1.00 24.97  ? 96   ARG B NH1   1 
ATOM   7758  N  NH2   . ARG B 2 81   ? 125.320 125.384 136.993 1.00 24.97  ? 96   ARG B NH2   1 
ATOM   7759  N  N     . GLU B 2 82   ? 120.148 122.576 140.229 1.00 34.87  ? 97   GLU B N     1 
ATOM   7760  C  CA    . GLU B 2 82   ? 119.339 121.496 140.764 1.00 34.87  ? 97   GLU B CA    1 
ATOM   7761  C  C     . GLU B 2 82   ? 120.161 120.215 140.862 1.00 34.87  ? 97   GLU B C     1 
ATOM   7762  O  O     . GLU B 2 82   ? 121.222 120.075 140.247 1.00 34.87  ? 97   GLU B O     1 
ATOM   7763  C  CB    . GLU B 2 82   ? 118.103 121.263 139.893 1.00 34.87  ? 97   GLU B CB    1 
ATOM   7764  C  CG    . GLU B 2 82   ? 117.027 122.330 140.031 1.00 34.87  ? 97   GLU B CG    1 
ATOM   7765  C  CD    . GLU B 2 82   ? 116.249 122.211 141.327 1.00 34.87  ? 97   GLU B CD    1 
ATOM   7766  O  OE1   . GLU B 2 82   ? 116.371 121.167 142.003 1.00 34.87  ? 97   GLU B OE1   1 
ATOM   7767  O  OE2   . GLU B 2 82   ? 115.514 123.160 141.671 1.00 34.87  ? 97   GLU B OE2   1 
ATOM   7768  N  N     . GLN B 2 83   ? 119.658 119.277 141.662 1.00 33.33  ? 98   GLN B N     1 
ATOM   7769  C  CA    . GLN B 2 83   ? 120.216 117.938 141.830 1.00 33.33  ? 98   GLN B CA    1 
ATOM   7770  C  C     . GLN B 2 83   ? 121.603 117.939 142.464 1.00 33.33  ? 98   GLN B C     1 
ATOM   7771  O  O     . GLN B 2 83   ? 122.307 116.925 142.400 1.00 33.33  ? 98   GLN B O     1 
ATOM   7772  C  CB    . GLN B 2 83   ? 120.251 117.178 140.499 1.00 33.33  ? 98   GLN B CB    1 
ATOM   7773  C  CG    . GLN B 2 83   ? 118.901 117.106 139.810 1.00 33.33  ? 98   GLN B CG    1 
ATOM   7774  C  CD    . GLN B 2 83   ? 117.825 116.530 140.709 1.00 33.33  ? 98   GLN B CD    1 
ATOM   7775  O  OE1   . GLN B 2 83   ? 118.053 115.551 141.420 1.00 33.33  ? 98   GLN B OE1   1 
ATOM   7776  N  NE2   . GLN B 2 83   ? 116.646 117.141 140.688 1.00 33.33  ? 98   GLN B NE2   1 
ATOM   7777  N  N     . VAL B 2 84   ? 122.022 119.045 143.073 1.00 23.81  ? 99   VAL B N     1 
ATOM   7778  C  CA    . VAL B 2 84   ? 123.268 119.109 143.827 1.00 23.81  ? 99   VAL B CA    1 
ATOM   7779  C  C     . VAL B 2 84   ? 122.927 119.464 145.265 1.00 23.81  ? 99   VAL B C     1 
ATOM   7780  O  O     . VAL B 2 84   ? 122.177 120.415 145.514 1.00 23.81  ? 99   VAL B O     1 
ATOM   7781  C  CB    . VAL B 2 84   ? 124.248 120.127 143.222 1.00 23.81  ? 99   VAL B CB    1 
ATOM   7782  C  CG1   . VAL B 2 84   ? 125.500 120.207 144.070 1.00 23.81  ? 99   VAL B CG1   1 
ATOM   7783  C  CG2   . VAL B 2 84   ? 124.593 119.744 141.801 1.00 23.81  ? 99   VAL B CG2   1 
ATOM   7784  N  N     . PHE B 2 85   ? 123.473 118.706 146.206 1.00 22.84  ? 100  PHE B N     1 
ATOM   7785  C  CA    . PHE B 2 85   ? 123.112 118.831 147.609 1.00 22.84  ? 100  PHE B CA    1 
ATOM   7786  C  C     . PHE B 2 85   ? 124.336 119.220 148.436 1.00 22.84  ? 100  PHE B C     1 
ATOM   7787  O  O     . PHE B 2 85   ? 125.400 119.546 147.905 1.00 22.84  ? 100  PHE B O     1 
ATOM   7788  C  CB    . PHE B 2 85   ? 122.485 117.530 148.106 1.00 22.84  ? 100  PHE B CB    1 
ATOM   7789  C  CG    . PHE B 2 85   ? 121.380 117.024 147.230 1.00 22.84  ? 100  PHE B CG    1 
ATOM   7790  C  CD1   . PHE B 2 85   ? 120.102 117.542 147.339 1.00 22.84  ? 100  PHE B CD1   1 
ATOM   7791  C  CD2   . PHE B 2 85   ? 121.619 116.031 146.297 1.00 22.84  ? 100  PHE B CD2   1 
ATOM   7792  C  CE1   . PHE B 2 85   ? 119.084 117.079 146.535 1.00 22.84  ? 100  PHE B CE1   1 
ATOM   7793  C  CE2   . PHE B 2 85   ? 120.605 115.564 145.490 1.00 22.84  ? 100  PHE B CE2   1 
ATOM   7794  C  CZ    . PHE B 2 85   ? 119.335 116.088 145.609 1.00 22.84  ? 100  PHE B CZ    1 
ATOM   7795  N  N     . ALA B 2 86   ? 124.167 119.187 149.754 1.00 23.09  ? 101  ALA B N     1 
ATOM   7796  C  CA    . ALA B 2 86   ? 125.205 119.558 150.702 1.00 23.09  ? 101  ALA B CA    1 
ATOM   7797  C  C     . ALA B 2 86   ? 125.632 118.336 151.501 1.00 23.09  ? 101  ALA B C     1 
ATOM   7798  O  O     . ALA B 2 86   ? 124.818 117.452 151.785 1.00 23.09  ? 101  ALA B O     1 
ATOM   7799  C  CB    . ALA B 2 86   ? 124.714 120.651 151.652 1.00 23.09  ? 101  ALA B CB    1 
ATOM   7800  N  N     . VAL B 2 87   ? 126.911 118.291 151.863 1.00 26.74  ? 102  VAL B N     1 
ATOM   7801  C  CA    . VAL B 2 87   ? 127.486 117.164 152.583 1.00 26.74  ? 102  VAL B CA    1 
ATOM   7802  C  C     . VAL B 2 87   ? 128.318 117.687 153.745 1.00 26.74  ? 102  VAL B C     1 
ATOM   7803  O  O     . VAL B 2 87   ? 129.050 118.672 153.604 1.00 26.74  ? 102  VAL B O     1 
ATOM   7804  C  CB    . VAL B 2 87   ? 128.338 116.281 151.645 1.00 26.74  ? 102  VAL B CB    1 
ATOM   7805  C  CG1   . VAL B 2 87   ? 129.239 115.357 152.440 1.00 26.74  ? 102  VAL B CG1   1 
ATOM   7806  C  CG2   . VAL B 2 87   ? 127.437 115.476 150.742 1.00 26.74  ? 102  VAL B CG2   1 
ATOM   7807  N  N     . ASP B 2 88   ? 128.192 117.032 154.897 1.00 35.70  ? 103  ASP B N     1 
ATOM   7808  C  CA    . ASP B 2 88   ? 129.020 117.301 156.064 1.00 35.70  ? 103  ASP B CA    1 
ATOM   7809  C  C     . ASP B 2 88   ? 129.920 116.100 156.312 1.00 35.70  ? 103  ASP B C     1 
ATOM   7810  O  O     . ASP B 2 88   ? 129.438 114.965 156.386 1.00 35.70  ? 103  ASP B O     1 
ATOM   7811  C  CB    . ASP B 2 88   ? 128.157 117.585 157.295 1.00 35.70  ? 103  ASP B CB    1 
ATOM   7812  C  CG    . ASP B 2 88   ? 127.057 116.559 157.479 1.00 35.70  ? 103  ASP B CG    1 
ATOM   7813  O  OD1   . ASP B 2 88   ? 126.426 116.174 156.471 1.00 35.70  ? 103  ASP B OD1   1 
ATOM   7814  O  OD2   . ASP B 2 88   ? 126.826 116.133 158.630 1.00 35.70  ? 103  ASP B OD2   1 
ATOM   7815  N  N     . SER B 2 89   ? 131.221 116.348 156.436 1.00 33.01  ? 104  SER B N     1 
ATOM   7816  C  CA    . SER B 2 89   ? 132.192 115.280 156.611 1.00 33.01  ? 104  SER B CA    1 
ATOM   7817  C  C     . SER B 2 89   ? 133.176 115.655 157.707 1.00 33.01  ? 104  SER B C     1 
ATOM   7818  O  O     . SER B 2 89   ? 133.560 116.819 157.847 1.00 33.01  ? 104  SER B O     1 
ATOM   7819  C  CB    . SER B 2 89   ? 132.947 114.986 155.311 1.00 33.01  ? 104  SER B CB    1 
ATOM   7820  O  OG    . SER B 2 89   ? 132.055 114.590 154.286 1.00 33.01  ? 104  SER B OG    1 
ATOM   7821  N  N     . LEU B 2 90   ? 133.584 114.652 158.477 1.00 38.59  ? 105  LEU B N     1 
ATOM   7822  C  CA    . LEU B 2 90   ? 134.521 114.856 159.569 1.00 38.59  ? 105  LEU B CA    1 
ATOM   7823  C  C     . LEU B 2 90   ? 135.940 115.030 159.035 1.00 38.59  ? 105  LEU B C     1 
ATOM   7824  O  O     . LEU B 2 90   ? 136.261 114.651 157.906 1.00 38.59  ? 105  LEU B O     1 
ATOM   7825  C  CB    . LEU B 2 90   ? 134.468 113.682 160.544 1.00 38.59  ? 105  LEU B CB    1 
ATOM   7826  C  CG    . LEU B 2 90   ? 133.077 113.300 161.050 1.00 38.59  ? 105  LEU B CG    1 
ATOM   7827  C  CD1   . LEU B 2 90   ? 133.152 112.115 161.998 1.00 38.59  ? 105  LEU B CD1   1 
ATOM   7828  C  CD2   . LEU B 2 90   ? 132.410 114.488 161.721 1.00 38.59  ? 105  LEU B CD2   1 
ATOM   7829  N  N     . HIS B 2 91   ? 136.794 115.618 159.871 1.00 40.65  ? 106  HIS B N     1 
ATOM   7830  C  CA    . HIS B 2 91   ? 138.198 115.828 159.540 1.00 40.65  ? 106  HIS B CA    1 
ATOM   7831  C  C     . HIS B 2 91   ? 139.060 114.600 159.799 1.00 40.65  ? 106  HIS B C     1 
ATOM   7832  O  O     . HIS B 2 91   ? 140.289 114.718 159.790 1.00 40.65  ? 106  HIS B O     1 
ATOM   7833  C  CB    . HIS B 2 91   ? 138.766 117.007 160.335 1.00 40.65  ? 106  HIS B CB    1 
ATOM   7834  C  CG    . HIS B 2 91   ? 138.119 118.321 160.031 1.00 40.65  ? 106  HIS B CG    1 
ATOM   7835  N  ND1   . HIS B 2 91   ? 136.753 118.502 160.038 1.00 40.65  ? 106  HIS B ND1   1 
ATOM   7836  C  CD2   . HIS B 2 91   ? 138.656 119.527 159.731 1.00 40.65  ? 106  HIS B CD2   1 
ATOM   7837  C  CE1   . HIS B 2 91   ? 136.476 119.760 159.746 1.00 40.65  ? 106  HIS B CE1   1 
ATOM   7838  N  NE2   . HIS B 2 91   ? 137.614 120.404 159.555 1.00 40.65  ? 106  HIS B NE2   1 
ATOM   7839  N  N     . GLN B 2 92   ? 138.461 113.437 160.042 1.00 51.98  ? 107  GLN B N     1 
ATOM   7840  C  CA    . GLN B 2 92   ? 139.210 112.226 160.356 1.00 51.98  ? 107  GLN B CA    1 
ATOM   7841  C  C     . GLN B 2 92   ? 138.609 111.047 159.608 1.00 51.98  ? 107  GLN B C     1 
ATOM   7842  O  O     . GLN B 2 92   ? 137.449 110.687 159.837 1.00 51.98  ? 107  GLN B O     1 
ATOM   7843  C  CB    . GLN B 2 92   ? 139.220 111.958 161.864 1.00 51.98  ? 107  GLN B CB    1 
ATOM   7844  C  CG    . GLN B 2 92   ? 137.874 112.134 162.542 1.00 51.98  ? 107  GLN B CG    1 
ATOM   7845  C  CD    . GLN B 2 92   ? 137.870 111.611 163.961 1.00 51.98  ? 107  GLN B CD    1 
ATOM   7846  O  OE1   . GLN B 2 92   ? 138.797 110.920 164.382 1.00 51.98  ? 107  GLN B OE1   1 
ATOM   7847  N  NE2   . GLN B 2 92   ? 136.824 111.939 164.710 1.00 51.98  ? 107  GLN B NE2   1 
ATOM   7848  N  N     . GLU B 2 93   ? 139.390 110.457 158.713 1.00 57.62  ? 108  GLU B N     1 
ATOM   7849  C  CA    . GLU B 2 93   ? 138.975 109.222 158.065 1.00 57.62  ? 108  GLU B CA    1 
ATOM   7850  C  C     . GLU B 2 93   ? 139.152 108.047 159.024 1.00 57.62  ? 108  GLU B C     1 
ATOM   7851  O  O     . GLU B 2 93   ? 140.156 107.975 159.737 1.00 57.62  ? 108  GLU B O     1 
ATOM   7852  C  CB    . GLU B 2 93   ? 139.790 108.978 156.799 1.00 57.62  ? 108  GLU B CB    1 
ATOM   7853  C  CG    . GLU B 2 93   ? 139.766 110.121 155.803 1.00 57.62  ? 108  GLU B CG    1 
ATOM   7854  C  CD    . GLU B 2 93   ? 140.672 109.865 154.617 1.00 57.62  ? 108  GLU B CD    1 
ATOM   7855  O  OE1   . GLU B 2 93   ? 141.330 108.804 154.591 1.00 57.62  ? 108  GLU B OE1   1 
ATOM   7856  O  OE2   . GLU B 2 93   ? 140.728 110.722 153.711 1.00 57.62  ? 108  GLU B OE2   1 
ATOM   7857  N  N     . PRO B 2 94   ? 138.196 107.121 159.070 1.00 57.33  ? 109  PRO B N     1 
ATOM   7858  C  CA    . PRO B 2 94   ? 138.362 105.941 159.924 1.00 57.33  ? 109  PRO B CA    1 
ATOM   7859  C  C     . PRO B 2 94   ? 139.524 105.080 159.453 1.00 57.33  ? 109  PRO B C     1 
ATOM   7860  O  O     . PRO B 2 94   ? 139.786 104.950 158.256 1.00 57.33  ? 109  PRO B O     1 
ATOM   7861  C  CB    . PRO B 2 94   ? 137.024 105.207 159.780 1.00 57.33  ? 109  PRO B CB    1 
ATOM   7862  C  CG    . PRO B 2 94   ? 136.490 105.657 158.461 1.00 57.33  ? 109  PRO B CG    1 
ATOM   7863  C  CD    . PRO B 2 94   ? 136.935 107.085 158.309 1.00 57.33  ? 109  PRO B CD    1 
ATOM   7864  N  N     . GLY B 2 95   ? 140.221 104.486 160.416 1.00 56.39  ? 110  GLY B N     1 
ATOM   7865  C  CA    . GLY B 2 95   ? 141.358 103.634 160.117 1.00 56.39  ? 110  GLY B CA    1 
ATOM   7866  C  C     . GLY B 2 95   ? 142.523 104.376 159.491 1.00 56.39  ? 110  GLY B C     1 
ATOM   7867  O  O     . GLY B 2 95   ? 143.136 103.897 158.537 1.00 56.39  ? 110  GLY B O     1 
ATOM   7868  N  N     . ASP B 2 101  ? 148.906 104.767 151.998 1.00 60.12  ? 116  ASP B N     1 
ATOM   7869  C  CA    . ASP B 2 101  ? 148.515 106.152 152.235 1.00 60.12  ? 116  ASP B CA    1 
ATOM   7870  C  C     . ASP B 2 101  ? 149.607 106.925 152.964 1.00 60.12  ? 116  ASP B C     1 
ATOM   7871  O  O     . ASP B 2 101  ? 150.371 106.357 153.744 1.00 60.12  ? 116  ASP B O     1 
ATOM   7872  C  CB    . ASP B 2 101  ? 147.215 106.214 153.041 1.00 60.12  ? 116  ASP B CB    1 
ATOM   7873  C  CG    . ASP B 2 101  ? 146.027 105.664 152.279 1.00 60.12  ? 116  ASP B CG    1 
ATOM   7874  O  OD1   . ASP B 2 101  ? 145.995 105.809 151.039 1.00 60.12  ? 116  ASP B OD1   1 
ATOM   7875  O  OD2   . ASP B 2 101  ? 145.125 105.088 152.922 1.00 60.12  ? 116  ASP B OD2   1 
ATOM   7876  N  N     . SER B 2 102  ? 149.675 108.227 152.700 1.00 57.66  ? 117  SER B N     1 
ATOM   7877  C  CA    . SER B 2 102  ? 150.575 109.128 153.405 1.00 57.66  ? 117  SER B CA    1 
ATOM   7878  C  C     . SER B 2 102  ? 149.838 110.015 154.399 1.00 57.66  ? 117  SER B C     1 
ATOM   7879  O  O     . SER B 2 102  ? 150.404 111.006 154.872 1.00 57.66  ? 117  SER B O     1 
ATOM   7880  C  CB    . SER B 2 102  ? 151.350 109.989 152.406 1.00 57.66  ? 117  SER B CB    1 
ATOM   7881  O  OG    . SER B 2 102  ? 152.252 110.857 153.071 1.00 57.66  ? 117  SER B OG    1 
ATOM   7882  N  N     . ALA B 2 103  ? 148.589 109.685 154.718 1.00 55.59  ? 118  ALA B N     1 
ATOM   7883  C  CA    . ALA B 2 103  ? 147.799 110.502 155.627 1.00 55.59  ? 118  ALA B CA    1 
ATOM   7884  C  C     . ALA B 2 103  ? 148.367 110.443 157.039 1.00 55.59  ? 118  ALA B C     1 
ATOM   7885  O  O     . ALA B 2 103  ? 148.796 109.386 157.511 1.00 55.59  ? 118  ALA B O     1 
ATOM   7886  C  CB    . ALA B 2 103  ? 146.343 110.036 155.627 1.00 55.59  ? 118  ALA B CB    1 
ATOM   7887  N  N     . PHE B 2 104  ? 148.368 111.590 157.713 1.00 52.71  ? 119  PHE B N     1 
ATOM   7888  C  CA    . PHE B 2 104  ? 148.839 111.652 159.087 1.00 52.71  ? 119  PHE B CA    1 
ATOM   7889  C  C     . PHE B 2 104  ? 147.918 110.857 160.002 1.00 52.71  ? 119  PHE B C     1 
ATOM   7890  O  O     . PHE B 2 104  ? 146.726 110.698 159.734 1.00 52.71  ? 119  PHE B O     1 
ATOM   7891  C  CB    . PHE B 2 104  ? 148.916 113.098 159.565 1.00 52.71  ? 119  PHE B CB    1 
ATOM   7892  C  CG    . PHE B 2 104  ? 149.734 113.977 158.679 1.00 52.71  ? 119  PHE B CG    1 
ATOM   7893  C  CD1   . PHE B 2 104  ? 151.089 114.132 158.901 1.00 52.71  ? 119  PHE B CD1   1 
ATOM   7894  C  CD2   . PHE B 2 104  ? 149.150 114.647 157.621 1.00 52.71  ? 119  PHE B CD2   1 
ATOM   7895  C  CE1   . PHE B 2 104  ? 151.848 114.942 158.084 1.00 52.71  ? 119  PHE B CE1   1 
ATOM   7896  C  CE2   . PHE B 2 104  ? 149.901 115.458 156.800 1.00 52.71  ? 119  PHE B CE2   1 
ATOM   7897  C  CZ    . PHE B 2 104  ? 151.253 115.607 157.031 1.00 52.71  ? 119  PHE B CZ    1 
ATOM   7898  N  N     . ARG B 2 105  ? 148.485 110.360 161.093 1.00 53.97  ? 120  ARG B N     1 
ATOM   7899  C  CA    . ARG B 2 105  ? 147.766 109.517 162.032 1.00 53.97  ? 120  ARG B CA    1 
ATOM   7900  C  C     . ARG B 2 105  ? 147.522 110.268 163.333 1.00 53.97  ? 120  ARG B C     1 
ATOM   7901  O  O     . ARG B 2 105  ? 148.290 111.155 163.714 1.00 53.97  ? 120  ARG B O     1 
ATOM   7902  C  CB    . ARG B 2 105  ? 148.543 108.229 162.311 1.00 53.97  ? 120  ARG B CB    1 
ATOM   7903  C  CG    . ARG B 2 105  ? 148.806 107.395 161.073 1.00 53.97  ? 120  ARG B CG    1 
ATOM   7904  C  CD    . ARG B 2 105  ? 147.536 106.733 160.573 1.00 53.97  ? 120  ARG B CD    1 
ATOM   7905  N  NE    . ARG B 2 105  ? 147.736 106.084 159.284 1.00 53.97  ? 120  ARG B NE    1 
ATOM   7906  C  CZ    . ARG B 2 105  ? 146.836 105.319 158.684 1.00 53.97  ? 120  ARG B CZ    1 
ATOM   7907  N  NH1   . ARG B 2 105  ? 145.663 105.065 159.240 1.00 53.97  ? 120  ARG B NH1   1 
ATOM   7908  N  NH2   . ARG B 2 105  ? 147.120 104.794 157.495 1.00 53.97  ? 120  ARG B NH2   1 
ATOM   7909  N  N     . LEU B 2 106  ? 146.438 109.904 164.010 1.00 57.27  ? 121  LEU B N     1 
ATOM   7910  C  CA    . LEU B 2 106  ? 146.072 110.493 165.292 1.00 57.27  ? 121  LEU B CA    1 
ATOM   7911  C  C     . LEU B 2 106  ? 146.419 109.493 166.389 1.00 57.27  ? 121  LEU B C     1 
ATOM   7912  O  O     . LEU B 2 106  ? 145.740 108.473 166.546 1.00 57.27  ? 121  LEU B O     1 
ATOM   7913  C  CB    . LEU B 2 106  ? 144.588 110.852 165.324 1.00 57.27  ? 121  LEU B CB    1 
ATOM   7914  C  CG    . LEU B 2 106  ? 144.059 111.717 164.178 1.00 57.27  ? 121  LEU B CG    1 
ATOM   7915  C  CD1   . LEU B 2 106  ? 142.578 112.001 164.359 1.00 57.27  ? 121  LEU B CD1   1 
ATOM   7916  C  CD2   . LEU B 2 106  ? 144.844 113.010 164.071 1.00 57.27  ? 121  LEU B CD2   1 
ATOM   7917  N  N     . VAL B 2 107  ? 147.471 109.788 167.148 1.00 60.76  ? 122  VAL B N     1 
ATOM   7918  C  CA    . VAL B 2 107  ? 147.951 108.914 168.211 1.00 60.76  ? 122  VAL B CA    1 
ATOM   7919  C  C     . VAL B 2 107  ? 147.690 109.591 169.550 1.00 60.76  ? 122  VAL B C     1 
ATOM   7920  O  O     . VAL B 2 107  ? 148.060 110.754 169.751 1.00 60.76  ? 122  VAL B O     1 
ATOM   7921  C  CB    . VAL B 2 107  ? 149.442 108.574 168.033 1.00 60.76  ? 122  VAL B CB    1 
ATOM   7922  C  CG1   . VAL B 2 107  ? 149.624 107.634 166.854 1.00 60.76  ? 122  VAL B CG1   1 
ATOM   7923  C  CG2   . VAL B 2 107  ? 150.265 109.835 167.825 1.00 60.76  ? 122  VAL B CG2   1 
ATOM   7924  N  N     . SER B 2 108  ? 147.036 108.871 170.452 1.00 63.55  ? 123  SER B N     1 
ATOM   7925  C  CA    . SER B 2 108  ? 146.719 109.417 171.764 1.00 63.55  ? 123  SER B CA    1 
ATOM   7926  C  C     . SER B 2 108  ? 147.959 109.382 172.650 1.00 63.55  ? 123  SER B C     1 
ATOM   7927  O  O     . SER B 2 108  ? 148.540 108.308 172.839 1.00 63.55  ? 123  SER B O     1 
ATOM   7928  C  CB    . SER B 2 108  ? 145.587 108.630 172.411 1.00 63.55  ? 123  SER B CB    1 
ATOM   7929  O  OG    . SER B 2 108  ? 145.230 109.187 173.663 1.00 63.55  ? 123  SER B OG    1 
ATOM   7930  N  N     . PRO B 2 109  ? 148.399 110.516 173.199 1.00 60.19  ? 124  PRO B N     1 
ATOM   7931  C  CA    . PRO B 2 109  ? 149.569 110.491 174.092 1.00 60.19  ? 124  PRO B CA    1 
ATOM   7932  C  C     . PRO B 2 109  ? 149.341 109.710 175.374 1.00 60.19  ? 124  PRO B C     1 
ATOM   7933  O  O     . PRO B 2 109  ? 150.320 109.345 176.037 1.00 60.19  ? 124  PRO B O     1 
ATOM   7934  C  CB    . PRO B 2 109  ? 149.827 111.978 174.375 1.00 60.19  ? 124  PRO B CB    1 
ATOM   7935  C  CG    . PRO B 2 109  ? 148.518 112.644 174.126 1.00 60.19  ? 124  PRO B CG    1 
ATOM   7936  C  CD    . PRO B 2 109  ? 147.869 111.877 173.014 1.00 60.19  ? 124  PRO B CD    1 
ATOM   7937  N  N     . GLU B 2 110  ? 148.086 109.451 175.753 1.00 61.89  ? 125  GLU B N     1 
ATOM   7938  C  CA    . GLU B 2 110  ? 147.824 108.620 176.924 1.00 61.89  ? 125  GLU B CA    1 
ATOM   7939  C  C     . GLU B 2 110  ? 148.358 107.207 176.726 1.00 61.89  ? 125  GLU B C     1 
ATOM   7940  O  O     . GLU B 2 110  ? 148.931 106.616 177.649 1.00 61.89  ? 125  GLU B O     1 
ATOM   7941  C  CB    . GLU B 2 110  ? 146.327 108.586 177.226 1.00 61.89  ? 125  GLU B CB    1 
ATOM   7942  C  CG    . GLU B 2 110  ? 145.772 109.881 177.790 1.00 61.89  ? 125  GLU B CG    1 
ATOM   7943  C  CD    . GLU B 2 110  ? 144.337 109.740 178.253 1.00 61.89  ? 125  GLU B CD    1 
ATOM   7944  O  OE1   . GLU B 2 110  ? 143.743 108.666 178.024 1.00 61.89  ? 125  GLU B OE1   1 
ATOM   7945  O  OE2   . GLU B 2 110  ? 143.804 110.700 178.848 1.00 61.89  ? 125  GLU B OE2   1 
ATOM   7946  N  N     . SER B 2 111  ? 148.180 106.649 175.529 1.00 59.07  ? 126  SER B N     1 
ATOM   7947  C  CA    . SER B 2 111  ? 148.697 105.323 175.225 1.00 59.07  ? 126  SER B CA    1 
ATOM   7948  C  C     . SER B 2 111  ? 150.188 105.325 174.920 1.00 59.07  ? 126  SER B C     1 
ATOM   7949  O  O     . SER B 2 111  ? 150.770 104.249 174.748 1.00 59.07  ? 126  SER B O     1 
ATOM   7950  C  CB    . SER B 2 111  ? 147.934 104.720 174.043 1.00 59.07  ? 126  SER B CB    1 
ATOM   7951  O  OG    . SER B 2 111  ? 146.544 104.658 174.311 1.00 59.07  ? 126  SER B OG    1 
ATOM   7952  N  N     . ILE B 2 112  ? 150.816 106.495 174.848 1.00 61.54  ? 127  ILE B N     1 
ATOM   7953  C  CA    . ILE B 2 112  ? 152.246 106.585 174.586 1.00 61.54  ? 127  ILE B CA    1 
ATOM   7954  C  C     . ILE B 2 112  ? 152.960 107.220 175.773 1.00 61.54  ? 127  ILE B C     1 
ATOM   7955  O  O     . ILE B 2 112  ? 153.410 106.525 176.683 1.00 61.54  ? 127  ILE B O     1 
ATOM   7956  C  CB    . ILE B 2 112  ? 152.527 107.374 173.298 1.00 61.54  ? 127  ILE B CB    1 
ATOM   7957  C  CG1   . ILE B 2 112  ? 151.883 106.678 172.097 1.00 61.54  ? 127  ILE B CG1   1 
ATOM   7958  C  CG2   . ILE B 2 112  ? 154.024 107.533 173.089 1.00 61.54  ? 127  ILE B CG2   1 
ATOM   7959  C  CD1   . ILE B 2 112  ? 152.102 107.399 170.785 1.00 61.54  ? 127  ILE B CD1   1 
ATOM   7960  N  N     . LEU B 2 130  ? 154.575 100.920 167.761 1.00 68.60  ? 145  LEU B N     1 
ATOM   7961  C  CA    . LEU B 2 130  ? 154.555 101.425 166.393 1.00 68.60  ? 145  LEU B CA    1 
ATOM   7962  C  C     . LEU B 2 130  ? 153.669 100.572 165.495 1.00 68.60  ? 145  LEU B C     1 
ATOM   7963  O  O     . LEU B 2 130  ? 153.091 101.069 164.530 1.00 68.60  ? 145  LEU B O     1 
ATOM   7964  C  CB    . LEU B 2 130  ? 155.974 101.486 165.825 1.00 68.60  ? 145  LEU B CB    1 
ATOM   7965  C  CG    . LEU B 2 130  ? 156.775 102.748 166.142 1.00 68.60  ? 145  LEU B CG    1 
ATOM   7966  C  CD1   . LEU B 2 130  ? 158.238 102.558 165.781 1.00 68.60  ? 145  LEU B CD1   1 
ATOM   7967  C  CD2   . LEU B 2 130  ? 156.193 103.944 165.402 1.00 68.60  ? 145  LEU B CD2   1 
ATOM   7968  N  N     . GLU B 2 131  ? 153.572 99.279  165.812 1.00 71.89  ? 146  GLU B N     1 
ATOM   7969  C  CA    . GLU B 2 131  ? 152.714 98.395  165.030 1.00 71.89  ? 146  GLU B CA    1 
ATOM   7970  C  C     . GLU B 2 131  ? 151.245 98.760  165.197 1.00 71.89  ? 146  GLU B C     1 
ATOM   7971  O  O     . GLU B 2 131  ? 150.475 98.717  164.231 1.00 71.89  ? 146  GLU B O     1 
ATOM   7972  C  CB    . GLU B 2 131  ? 152.954 96.939  165.426 1.00 71.89  ? 146  GLU B CB    1 
ATOM   7973  C  CG    . GLU B 2 131  ? 152.015 95.959  164.744 1.00 71.89  ? 146  GLU B CG    1 
ATOM   7974  C  CD    . GLU B 2 131  ? 152.047 96.079  163.233 1.00 71.89  ? 146  GLU B CD    1 
ATOM   7975  O  OE1   . GLU B 2 131  ? 153.156 96.175  162.667 1.00 71.89  ? 146  GLU B OE1   1 
ATOM   7976  O  OE2   . GLU B 2 131  ? 150.964 96.085  162.612 1.00 71.89  ? 146  GLU B OE2   1 
ATOM   7977  N  N     . ASN B 2 132  ? 150.839 99.122  166.412 1.00 73.38  ? 147  ASN B N     1 
ATOM   7978  C  CA    . ASN B 2 132  ? 149.446 99.449  166.680 1.00 73.38  ? 147  ASN B CA    1 
ATOM   7979  C  C     . ASN B 2 132  ? 149.068 100.856 166.234 1.00 73.38  ? 147  ASN B C     1 
ATOM   7980  O  O     . ASN B 2 132  ? 147.883 101.204 166.281 1.00 73.38  ? 147  ASN B O     1 
ATOM   7981  C  CB    . ASN B 2 132  ? 149.151 99.284  168.173 1.00 73.38  ? 147  ASN B CB    1 
ATOM   7982  C  CG    . ASN B 2 132  ? 147.684 99.023  168.451 1.00 73.38  ? 147  ASN B CG    1 
ATOM   7983  O  OD1   . ASN B 2 132  ? 146.983 98.423  167.636 1.00 73.38  ? 147  ASN B OD1   1 
ATOM   7984  N  ND2   . ASN B 2 132  ? 147.213 99.473  169.607 1.00 73.38  ? 147  ASN B ND2   1 
ATOM   7985  N  N     . LEU B 2 133  ? 150.034 101.669 165.807 1.00 69.90  ? 148  LEU B N     1 
ATOM   7986  C  CA    . LEU B 2 133  ? 149.745 103.028 165.370 1.00 69.90  ? 148  LEU B CA    1 
ATOM   7987  C  C     . LEU B 2 133  ? 149.354 103.116 163.901 1.00 69.90  ? 148  LEU B C     1 
ATOM   7988  O  O     . LEU B 2 133  ? 148.998 104.205 163.440 1.00 69.90  ? 148  LEU B O     1 
ATOM   7989  C  CB    . LEU B 2 133  ? 150.953 103.935 165.619 1.00 69.90  ? 148  LEU B CB    1 
ATOM   7990  C  CG    . LEU B 2 133  ? 151.473 104.035 167.054 1.00 69.90  ? 148  LEU B CG    1 
ATOM   7991  C  CD1   . LEU B 2 133  ? 152.500 105.151 167.163 1.00 69.90  ? 148  LEU B CD1   1 
ATOM   7992  C  CD2   . LEU B 2 133  ? 150.333 104.247 168.037 1.00 69.90  ? 148  LEU B CD2   1 
ATOM   7993  N  N     . LEU B 2 134  ? 149.414 102.011 163.157 1.00 66.69  ? 149  LEU B N     1 
ATOM   7994  C  CA    . LEU B 2 134  ? 149.105 102.020 161.732 1.00 66.69  ? 149  LEU B CA    1 
ATOM   7995  C  C     . LEU B 2 134  ? 148.018 101.015 161.369 1.00 66.69  ? 149  LEU B C     1 
ATOM   7996  O  O     . LEU B 2 134  ? 147.853 100.686 160.190 1.00 66.69  ? 149  LEU B O     1 
ATOM   7997  C  CB    . LEU B 2 134  ? 150.369 101.756 160.911 1.00 66.69  ? 149  LEU B CB    1 
ATOM   7998  C  CG    . LEU B 2 134  ? 151.527 102.734 161.122 1.00 66.69  ? 149  LEU B CG    1 
ATOM   7999  C  CD1   . LEU B 2 134  ? 152.707 102.374 160.233 1.00 66.69  ? 149  LEU B CD1   1 
ATOM   8000  C  CD2   . LEU B 2 134  ? 151.078 104.163 160.868 1.00 66.69  ? 149  LEU B CD2   1 
ATOM   8001  N  N     . LYS B 2 135  ? 147.277 100.523 162.347 1.00 73.43  ? 150  LYS B N     1 
ATOM   8002  C  CA    . LYS B 2 135  ? 146.194 99.584  162.073 1.00 73.43  ? 150  LYS B CA    1 
ATOM   8003  C  C     . LYS B 2 135  ? 144.858 100.037 162.638 1.00 73.43  ? 150  LYS B C     1 
ATOM   8004  O  O     . LYS B 2 135  ? 143.822 99.816  162.004 1.00 73.43  ? 150  LYS B O     1 
ATOM   8005  C  CB    . LYS B 2 135  ? 146.548 98.190  162.625 1.00 73.43  ? 150  LYS B CB    1 
ATOM   8006  C  CG    . LYS B 2 135  ? 145.470 97.142  162.392 1.00 73.43  ? 150  LYS B CG    1 
ATOM   8007  C  CD    . LYS B 2 135  ? 145.885 95.779  162.919 1.00 73.43  ? 150  LYS B CD    1 
ATOM   8008  C  CE    . LYS B 2 135  ? 147.041 95.204  162.119 1.00 73.43  ? 150  LYS B CE    1 
ATOM   8009  N  NZ    . LYS B 2 135  ? 147.396 93.832  162.576 1.00 73.43  ? 150  LYS B NZ    1 
ATOM   8010  N  N     . THR B 2 136  ? 144.851 100.673 163.810 1.00 73.99  ? 151  THR B N     1 
ATOM   8011  C  CA    . THR B 2 136  ? 143.622 101.138 164.430 1.00 73.99  ? 151  THR B CA    1 
ATOM   8012  C  C     . THR B 2 136  ? 143.568 102.646 164.626 1.00 73.99  ? 151  THR B C     1 
ATOM   8013  O  O     . THR B 2 136  ? 142.509 103.163 165.000 1.00 73.99  ? 151  THR B O     1 
ATOM   8014  C  CB    . THR B 2 136  ? 143.418 100.457 165.793 1.00 73.99  ? 151  THR B CB    1 
ATOM   8015  O  OG1   . THR B 2 136  ? 144.461 100.859 166.689 1.00 73.99  ? 151  THR B OG1   1 
ATOM   8016  C  CG2   . THR B 2 136  ? 143.449 98.944  165.641 1.00 73.99  ? 151  THR B CG2   1 
ATOM   8017  N  N     . SER B 2 137  ? 144.664 103.360 164.388 1.00 62.97  ? 152  SER B N     1 
ATOM   8018  C  CA    . SER B 2 137  ? 144.685 104.800 164.593 1.00 62.97  ? 152  SER B CA    1 
ATOM   8019  C  C     . SER B 2 137  ? 143.898 105.520 163.503 1.00 62.97  ? 152  SER B C     1 
ATOM   8020  O  O     . SER B 2 137  ? 143.847 105.085 162.350 1.00 62.97  ? 152  SER B O     1 
ATOM   8021  C  CB    . SER B 2 137  ? 146.125 105.311 164.617 1.00 62.97  ? 152  SER B CB    1 
ATOM   8022  O  OG    . SER B 2 137  ? 146.162 106.718 164.774 1.00 62.97  ? 152  SER B OG    1 
ATOM   8023  N  N     . GLY B 2 138  ? 143.275 106.633 163.884 1.00 57.27  ? 153  GLY B N     1 
ATOM   8024  C  CA    . GLY B 2 138  ? 142.582 107.455 162.916 1.00 57.27  ? 153  GLY B CA    1 
ATOM   8025  C  C     . GLY B 2 138  ? 143.542 108.224 162.030 1.00 57.27  ? 153  GLY B C     1 
ATOM   8026  O  O     . GLY B 2 138  ? 144.723 108.386 162.332 1.00 57.27  ? 153  GLY B O     1 
ATOM   8027  N  N     . LYS B 2 139  ? 143.019 108.710 160.908 1.00 53.18  ? 154  LYS B N     1 
ATOM   8028  C  CA    . LYS B 2 139  ? 143.840 109.407 159.930 1.00 53.18  ? 154  LYS B CA    1 
ATOM   8029  C  C     . LYS B 2 139  ? 143.130 110.660 159.446 1.00 53.18  ? 154  LYS B C     1 
ATOM   8030  O  O     . LYS B 2 139  ? 141.917 110.648 159.220 1.00 53.18  ? 154  LYS B O     1 
ATOM   8031  C  CB    . LYS B 2 139  ? 144.171 108.499 158.741 1.00 53.18  ? 154  LYS B CB    1 
ATOM   8032  C  CG    . LYS B 2 139  ? 142.962 107.824 158.123 1.00 53.18  ? 154  LYS B CG    1 
ATOM   8033  C  CD    . LYS B 2 139  ? 143.367 106.891 157.000 1.00 53.18  ? 154  LYS B CD    1 
ATOM   8034  C  CE    . LYS B 2 139  ? 142.160 106.197 156.401 1.00 53.18  ? 154  LYS B CE    1 
ATOM   8035  N  NZ    . LYS B 2 139  ? 142.547 105.250 155.323 1.00 53.18  ? 154  LYS B NZ    1 
ATOM   8036  N  N     . LEU B 2 140  ? 143.892 111.739 159.293 1.00 42.42  ? 155  LEU B N     1 
ATOM   8037  C  CA    . LEU B 2 140  ? 143.344 112.967 158.739 1.00 42.42  ? 155  LEU B CA    1 
ATOM   8038  C  C     . LEU B 2 140  ? 143.022 112.789 157.262 1.00 42.42  ? 155  LEU B C     1 
ATOM   8039  O  O     . LEU B 2 140  ? 143.696 112.051 156.538 1.00 42.42  ? 155  LEU B O     1 
ATOM   8040  C  CB    . LEU B 2 140  ? 144.323 114.125 158.917 1.00 42.42  ? 155  LEU B CB    1 
ATOM   8041  C  CG    . LEU B 2 140  ? 144.615 114.571 160.346 1.00 42.42  ? 155  LEU B CG    1 
ATOM   8042  C  CD1   . LEU B 2 140  ? 145.415 115.859 160.337 1.00 42.42  ? 155  LEU B CD1   1 
ATOM   8043  C  CD2   . LEU B 2 140  ? 143.321 114.747 161.112 1.00 42.42  ? 155  LEU B CD2   1 
ATOM   8044  N  N     . ARG B 2 141  ? 141.979 113.479 156.814 1.00 38.02  ? 156  ARG B N     1 
ATOM   8045  C  CA    . ARG B 2 141  ? 141.550 113.378 155.428 1.00 38.02  ? 156  ARG B CA    1 
ATOM   8046  C  C     . ARG B 2 141  ? 142.480 114.165 154.514 1.00 38.02  ? 156  ARG B C     1 
ATOM   8047  O  O     . ARG B 2 141  ? 142.945 115.255 154.860 1.00 38.02  ? 156  ARG B O     1 
ATOM   8048  C  CB    . ARG B 2 141  ? 140.116 113.882 155.276 1.00 38.02  ? 156  ARG B CB    1 
ATOM   8049  C  CG    . ARG B 2 141  ? 139.938 115.352 155.590 1.00 38.02  ? 156  ARG B CG    1 
ATOM   8050  C  CD    . ARG B 2 141  ? 138.482 115.745 155.500 1.00 38.02  ? 156  ARG B CD    1 
ATOM   8051  N  NE    . ARG B 2 141  ? 138.301 117.188 155.569 1.00 38.02  ? 156  ARG B NE    1 
ATOM   8052  C  CZ    . ARG B 2 141  ? 137.121 117.784 155.647 1.00 38.02  ? 156  ARG B CZ    1 
ATOM   8053  N  NH1   . ARG B 2 141  ? 135.998 117.088 155.686 1.00 38.02  ? 156  ARG B NH1   1 
ATOM   8054  N  NH2   . ARG B 2 141  ? 137.067 119.111 155.688 1.00 38.02  ? 156  ARG B NH2   1 
ATOM   8055  N  N     . ALA B 2 142  ? 142.762 113.594 153.346 1.00 35.72  ? 157  ALA B N     1 
ATOM   8056  C  CA    . ALA B 2 142  ? 143.528 114.282 152.317 1.00 35.72  ? 157  ALA B CA    1 
ATOM   8057  C  C     . ALA B 2 142  ? 142.649 114.886 151.235 1.00 35.72  ? 157  ALA B C     1 
ATOM   8058  O  O     . ALA B 2 142  ? 143.044 115.876 150.611 1.00 35.72  ? 157  ALA B O     1 
ATOM   8059  C  CB    . ALA B 2 142  ? 144.534 113.324 151.671 1.00 35.72  ? 157  ALA B CB    1 
ATOM   8060  N  N     . THR B 2 143  ? 141.471 114.309 151.007 1.00 32.93  ? 158  THR B N     1 
ATOM   8061  C  CA    . THR B 2 143  ? 140.481 114.852 150.090 1.00 32.93  ? 158  THR B CA    1 
ATOM   8062  C  C     . THR B 2 143  ? 139.098 114.615 150.674 1.00 32.93  ? 158  THR B C     1 
ATOM   8063  O  O     . THR B 2 143  ? 138.899 113.731 151.510 1.00 32.93  ? 158  THR B O     1 
ATOM   8064  C  CB    . THR B 2 143  ? 140.570 114.219 148.695 1.00 32.93  ? 158  THR B CB    1 
ATOM   8065  O  OG1   . THR B 2 143  ? 140.714 112.799 148.820 1.00 32.93  ? 158  THR B OG1   1 
ATOM   8066  C  CG2   . THR B 2 143  ? 141.747 114.788 147.913 1.00 32.93  ? 158  THR B CG2   1 
ATOM   8067  N  N     . LEU B 2 144  ? 138.137 115.414 150.218 1.00 27.28  ? 159  LEU B N     1 
ATOM   8068  C  CA    . LEU B 2 144  ? 136.754 115.279 150.654 1.00 27.28  ? 159  LEU B CA    1 
ATOM   8069  C  C     . LEU B 2 144  ? 135.988 114.229 149.866 1.00 27.28  ? 159  LEU B C     1 
ATOM   8070  O  O     . LEU B 2 144  ? 134.800 114.024 150.134 1.00 27.28  ? 159  LEU B O     1 
ATOM   8071  C  CB    . LEU B 2 144  ? 136.032 116.622 150.545 1.00 27.28  ? 159  LEU B CB    1 
ATOM   8072  C  CG    . LEU B 2 144  ? 136.592 117.756 151.396 1.00 27.28  ? 159  LEU B CG    1 
ATOM   8073  C  CD1   . LEU B 2 144  ? 136.854 118.962 150.532 1.00 27.28  ? 159  LEU B CD1   1 
ATOM   8074  C  CD2   . LEU B 2 144  ? 135.626 118.099 152.506 1.00 27.28  ? 159  LEU B CD2   1 
ATOM   8075  N  N     . LEU B 2 145  ? 136.634 113.573 148.901 1.00 35.68  ? 160  LEU B N     1 
ATOM   8076  C  CA    . LEU B 2 145  ? 135.946 112.585 148.077 1.00 35.68  ? 160  LEU B CA    1 
ATOM   8077  C  C     . LEU B 2 145  ? 135.409 111.434 148.915 1.00 35.68  ? 160  LEU B C     1 
ATOM   8078  O  O     . LEU B 2 145  ? 134.283 110.972 148.696 1.00 35.68  ? 160  LEU B O     1 
ATOM   8079  C  CB    . LEU B 2 145  ? 136.893 112.063 146.998 1.00 35.68  ? 160  LEU B CB    1 
ATOM   8080  C  CG    . LEU B 2 145  ? 136.498 110.759 146.307 1.00 35.68  ? 160  LEU B CG    1 
ATOM   8081  C  CD1   . LEU B 2 145  ? 135.207 110.921 145.522 1.00 35.68  ? 160  LEU B CD1   1 
ATOM   8082  C  CD2   . LEU B 2 145  ? 137.621 110.284 145.405 1.00 35.68  ? 160  LEU B CD2   1 
ATOM   8083  N  N     . HIS B 2 146  ? 136.194 110.955 149.880 1.00 41.19  ? 161  HIS B N     1 
ATOM   8084  C  CA    . HIS B 2 146  ? 135.742 109.828 150.686 1.00 41.19  ? 161  HIS B CA    1 
ATOM   8085  C  C     . HIS B 2 146  ? 134.627 110.233 151.638 1.00 41.19  ? 161  HIS B C     1 
ATOM   8086  O  O     . HIS B 2 146  ? 133.790 109.399 152.000 1.00 41.19  ? 161  HIS B O     1 
ATOM   8087  C  CB    . HIS B 2 146  ? 136.920 109.222 151.448 1.00 41.19  ? 161  HIS B CB    1 
ATOM   8088  C  CG    . HIS B 2 146  ? 137.977 108.651 150.555 1.00 41.19  ? 161  HIS B CG    1 
ATOM   8089  N  ND1   . HIS B 2 146  ? 139.091 109.365 150.169 1.00 41.19  ? 161  HIS B ND1   1 
ATOM   8090  C  CD2   . HIS B 2 146  ? 138.081 107.440 149.958 1.00 41.19  ? 161  HIS B CD2   1 
ATOM   8091  C  CE1   . HIS B 2 146  ? 139.840 108.616 149.380 1.00 41.19  ? 161  HIS B CE1   1 
ATOM   8092  N  NE2   . HIS B 2 146  ? 139.249 107.443 149.236 1.00 41.19  ? 161  HIS B NE2   1 
ATOM   8093  N  N     . GLY B 2 147  ? 134.595 111.500 152.053 1.00 37.09  ? 162  GLY B N     1 
ATOM   8094  C  CA    . GLY B 2 147  ? 133.461 111.982 152.823 1.00 37.09  ? 162  GLY B CA    1 
ATOM   8095  C  C     . GLY B 2 147  ? 132.186 112.025 152.004 1.00 37.09  ? 162  GLY B C     1 
ATOM   8096  O  O     . GLY B 2 147  ? 131.108 111.683 152.498 1.00 37.09  ? 162  GLY B O     1 
ATOM   8097  N  N     . ALA B 2 148  ? 132.290 112.448 150.741 1.00 38.26  ? 163  ALA B N     1 
ATOM   8098  C  CA    . ALA B 2 148  ? 131.122 112.477 149.867 1.00 38.26  ? 163  ALA B CA    1 
ATOM   8099  C  C     . ALA B 2 148  ? 130.567 111.078 149.640 1.00 38.26  ? 163  ALA B C     1 
ATOM   8100  O  O     . ALA B 2 148  ? 129.348 110.874 149.670 1.00 38.26  ? 163  ALA B O     1 
ATOM   8101  C  CB    . ALA B 2 148  ? 131.480 113.133 148.536 1.00 38.26  ? 163  ALA B CB    1 
ATOM   8102  N  N     . LEU B 2 149  ? 131.445 110.099 149.415 1.00 43.29  ? 164  LEU B N     1 
ATOM   8103  C  CA    . LEU B 2 149  ? 131.000 108.731 149.181 1.00 43.29  ? 164  LEU B CA    1 
ATOM   8104  C  C     . LEU B 2 149  ? 130.378 108.094 150.416 1.00 43.29  ? 164  LEU B C     1 
ATOM   8105  O  O     . LEU B 2 149  ? 129.731 107.050 150.290 1.00 43.29  ? 164  LEU B O     1 
ATOM   8106  C  CB    . LEU B 2 149  ? 132.170 107.875 148.688 1.00 43.29  ? 164  LEU B CB    1 
ATOM   8107  C  CG    . LEU B 2 149  ? 132.883 108.354 147.420 1.00 43.29  ? 164  LEU B CG    1 
ATOM   8108  C  CD1   . LEU B 2 149  ? 133.945 107.360 146.984 1.00 43.29  ? 164  LEU B CD1   1 
ATOM   8109  C  CD2   . LEU B 2 149  ? 131.888 108.595 146.302 1.00 43.29  ? 164  LEU B CD2   1 
ATOM   8110  N  N     . GLU B 2 150  ? 130.555 108.690 151.597 1.00 47.84  ? 165  GLU B N     1 
ATOM   8111  C  CA    . GLU B 2 150  ? 129.872 108.209 152.792 1.00 47.84  ? 165  GLU B CA    1 
ATOM   8112  C  C     . GLU B 2 150  ? 128.403 108.613 152.811 1.00 47.84  ? 165  GLU B C     1 
ATOM   8113  O  O     . GLU B 2 150  ? 127.568 107.875 153.345 1.00 47.84  ? 165  GLU B O     1 
ATOM   8114  C  CB    . GLU B 2 150  ? 130.575 108.732 154.045 1.00 47.84  ? 165  GLU B CB    1 
ATOM   8115  C  CG    . GLU B 2 150  ? 131.887 108.035 154.359 1.00 47.84  ? 165  GLU B CG    1 
ATOM   8116  C  CD    . GLU B 2 150  ? 131.686 106.718 155.081 1.00 47.84  ? 165  GLU B CD    1 
ATOM   8117  O  OE1   . GLU B 2 150  ? 130.642 106.562 155.749 1.00 47.84  ? 165  GLU B OE1   1 
ATOM   8118  O  OE2   . GLU B 2 150  ? 132.568 105.840 154.981 1.00 47.84  ? 165  GLU B OE2   1 
ATOM   8119  N  N     . HIS B 2 151  ? 128.076 109.770 152.237 1.00 49.47  ? 166  HIS B N     1 
ATOM   8120  C  CA    . HIS B 2 151  ? 126.713 110.295 152.172 1.00 49.47  ? 166  HIS B CA    1 
ATOM   8121  C  C     . HIS B 2 151  ? 126.052 109.976 150.839 1.00 49.47  ? 166  HIS B C     1 
ATOM   8122  O  O     . HIS B 2 151  ? 125.297 110.792 150.303 1.00 49.47  ? 166  HIS B O     1 
ATOM   8123  C  CB    . HIS B 2 151  ? 126.710 111.801 152.418 1.00 49.47  ? 166  HIS B CB    1 
ATOM   8124  C  CG    . HIS B 2 151  ? 127.185 112.194 153.782 1.00 49.47  ? 166  HIS B CG    1 
ATOM   8125  N  ND1   . HIS B 2 151  ? 126.322 112.439 154.828 1.00 49.47  ? 166  HIS B ND1   1 
ATOM   8126  C  CD2   . HIS B 2 151  ? 128.432 112.390 154.269 1.00 49.47  ? 166  HIS B CD2   1 
ATOM   8127  C  CE1   . HIS B 2 151  ? 127.018 112.766 155.902 1.00 49.47  ? 166  HIS B CE1   1 
ATOM   8128  N  NE2   . HIS B 2 151  ? 128.301 112.744 155.590 1.00 49.47  ? 166  HIS B NE2   1 
ATOM   8129  N  N     . TYR B 2 152  ? 126.340 108.799 150.279 1.00 58.13  ? 167  TYR B N     1 
ATOM   8130  C  CA    . TYR B 2 152  ? 125.925 108.489 148.914 1.00 58.13  ? 167  TYR B CA    1 
ATOM   8131  C  C     . TYR B 2 152  ? 124.408 108.540 148.757 1.00 58.13  ? 167  TYR B C     1 
ATOM   8132  O  O     . TYR B 2 152  ? 123.895 109.125 147.796 1.00 58.13  ? 167  TYR B O     1 
ATOM   8133  C  CB    . TYR B 2 152  ? 126.472 107.119 148.516 1.00 58.13  ? 167  TYR B CB    1 
ATOM   8134  C  CG    . TYR B 2 152  ? 125.970 106.608 147.189 1.00 58.13  ? 167  TYR B CG    1 
ATOM   8135  C  CD1   . TYR B 2 152  ? 126.466 107.110 145.994 1.00 58.13  ? 167  TYR B CD1   1 
ATOM   8136  C  CD2   . TYR B 2 152  ? 125.012 105.608 147.132 1.00 58.13  ? 167  TYR B CD2   1 
ATOM   8137  C  CE1   . TYR B 2 152  ? 126.010 106.637 144.782 1.00 58.13  ? 167  TYR B CE1   1 
ATOM   8138  C  CE2   . TYR B 2 152  ? 124.550 105.131 145.928 1.00 58.13  ? 167  TYR B CE2   1 
ATOM   8139  C  CZ    . TYR B 2 152  ? 125.052 105.646 144.757 1.00 58.13  ? 167  TYR B CZ    1 
ATOM   8140  O  OH    . TYR B 2 152  ? 124.586 105.162 143.559 1.00 58.13  ? 167  TYR B OH    1 
ATOM   8141  N  N     . VAL B 2 153  ? 123.670 107.936 149.688 1.00 69.51  ? 168  VAL B N     1 
ATOM   8142  C  CA    . VAL B 2 153  ? 122.211 108.006 149.659 1.00 69.51  ? 168  VAL B CA    1 
ATOM   8143  C  C     . VAL B 2 153  ? 121.697 108.557 150.981 1.00 69.51  ? 168  VAL B C     1 
ATOM   8144  O  O     . VAL B 2 153  ? 121.014 109.587 151.009 1.00 69.51  ? 168  VAL B O     1 
ATOM   8145  C  CB    . VAL B 2 153  ? 121.581 106.633 149.354 1.00 69.51  ? 168  VAL B CB    1 
ATOM   8146  C  CG1   . VAL B 2 153  ? 120.114 106.624 149.756 1.00 69.51  ? 168  VAL B CG1   1 
ATOM   8147  C  CG2   . VAL B 2 153  ? 121.713 106.307 147.876 1.00 69.51  ? 168  VAL B CG2   1 
ATOM   8148  N  N     . ASN B 2 154  ? 122.024 107.877 152.078 1.00 66.56  ? 169  ASN B N     1 
ATOM   8149  C  CA    . ASN B 2 154  ? 121.577 108.263 153.416 1.00 66.56  ? 169  ASN B CA    1 
ATOM   8150  C  C     . ASN B 2 154  ? 120.063 108.445 153.487 1.00 66.56  ? 169  ASN B C     1 
ATOM   8151  O  O     . ASN B 2 154  ? 119.564 109.282 154.239 1.00 66.56  ? 169  ASN B O     1 
ATOM   8152  C  CB    . ASN B 2 154  ? 122.278 109.545 153.866 1.00 66.56  ? 169  ASN B CB    1 
ATOM   8153  C  CG    . ASN B 2 154  ? 123.763 109.350 154.083 1.00 66.56  ? 169  ASN B CG    1 
ATOM   8154  O  OD1   . ASN B 2 154  ? 124.366 108.429 153.533 1.00 66.56  ? 169  ASN B OD1   1 
ATOM   8155  N  ND2   . ASN B 2 154  ? 124.360 110.214 154.893 1.00 66.56  ? 169  ASN B ND2   1 
ATOM   8156  N  N     . ARG B 2 161  ? 117.347 108.885 145.432 1.00 73.13  ? 176  ARG B N     1 
ATOM   8157  C  CA    . ARG B 2 161  ? 117.613 107.634 144.732 1.00 73.13  ? 176  ARG B CA    1 
ATOM   8158  C  C     . ARG B 2 161  ? 117.632 107.845 143.221 1.00 73.13  ? 176  ARG B C     1 
ATOM   8159  O  O     . ARG B 2 161  ? 117.568 106.887 142.452 1.00 73.13  ? 176  ARG B O     1 
ATOM   8160  C  CB    . ARG B 2 161  ? 116.569 106.580 145.100 1.00 73.13  ? 176  ARG B CB    1 
ATOM   8161  C  CG    . ARG B 2 161  ? 116.395 106.370 146.593 1.00 73.13  ? 176  ARG B CG    1 
ATOM   8162  C  CD    . ARG B 2 161  ? 115.424 105.237 146.876 1.00 73.13  ? 176  ARG B CD    1 
ATOM   8163  N  NE    . ARG B 2 161  ? 115.943 103.952 146.422 1.00 73.13  ? 176  ARG B NE    1 
ATOM   8164  C  CZ    . ARG B 2 161  ? 116.666 103.132 147.172 1.00 73.13  ? 176  ARG B CZ    1 
ATOM   8165  N  NH1   . ARG B 2 161  ? 116.973 103.430 148.424 1.00 73.13  ? 176  ARG B NH1   1 
ATOM   8166  N  NH2   . ARG B 2 161  ? 117.090 101.983 146.654 1.00 73.13  ? 176  ARG B NH2   1 
ATOM   8167  N  N     . LYS B 2 162  ? 117.719 109.105 142.803 1.00 59.47  ? 177  LYS B N     1 
ATOM   8168  C  CA    . LYS B 2 162  ? 117.732 109.448 141.392 1.00 59.47  ? 177  LYS B CA    1 
ATOM   8169  C  C     . LYS B 2 162  ? 119.168 109.525 140.877 1.00 59.47  ? 177  LYS B C     1 
ATOM   8170  O  O     . LYS B 2 162  ? 120.134 109.272 141.600 1.00 59.47  ? 177  LYS B O     1 
ATOM   8171  C  CB    . LYS B 2 162  ? 116.994 110.764 141.157 1.00 59.47  ? 177  LYS B CB    1 
ATOM   8172  C  CG    . LYS B 2 162  ? 115.536 110.740 141.578 1.00 59.47  ? 177  LYS B CG    1 
ATOM   8173  C  CD    . LYS B 2 162  ? 114.757 109.688 140.811 1.00 59.47  ? 177  LYS B CD    1 
ATOM   8174  C  CE    . LYS B 2 162  ? 113.300 109.669 141.238 1.00 59.47  ? 177  LYS B CE    1 
ATOM   8175  N  NZ    . LYS B 2 162  ? 112.514 108.654 140.483 1.00 59.47  ? 177  LYS B NZ    1 
ATOM   8176  N  N     . LEU B 2 163  ? 119.305 109.884 139.604 1.00 42.04  ? 178  LEU B N     1 
ATOM   8177  C  CA    . LEU B 2 163  ? 120.591 109.951 138.924 1.00 42.04  ? 178  LEU B CA    1 
ATOM   8178  C  C     . LEU B 2 163  ? 120.414 110.701 137.609 1.00 42.04  ? 178  LEU B C     1 
ATOM   8179  O  O     . LEU B 2 163  ? 119.448 110.443 136.881 1.00 42.04  ? 178  LEU B O     1 
ATOM   8180  C  CB    . LEU B 2 163  ? 121.140 108.545 138.678 1.00 42.04  ? 178  LEU B CB    1 
ATOM   8181  C  CG    . LEU B 2 163  ? 122.586 108.407 138.206 1.00 42.04  ? 178  LEU B CG    1 
ATOM   8182  C  CD1   . LEU B 2 163  ? 123.545 108.867 139.290 1.00 42.04  ? 178  LEU B CD1   1 
ATOM   8183  C  CD2   . LEU B 2 163  ? 122.875 106.971 137.810 1.00 42.04  ? 178  LEU B CD2   1 
ATOM   8184  N  N     . PRO B 2 164  ? 121.312 111.631 137.260 1.00 34.45  ? 179  PRO B N     1 
ATOM   8185  C  CA    . PRO B 2 164  ? 122.507 112.075 137.994 1.00 34.45  ? 179  PRO B CA    1 
ATOM   8186  C  C     . PRO B 2 164  ? 122.188 112.961 139.190 1.00 34.45  ? 179  PRO B C     1 
ATOM   8187  O  O     . PRO B 2 164  ? 121.073 113.452 139.338 1.00 34.45  ? 179  PRO B O     1 
ATOM   8188  C  CB    . PRO B 2 164  ? 123.300 112.863 136.933 1.00 34.45  ? 179  PRO B CB    1 
ATOM   8189  C  CG    . PRO B 2 164  ? 122.677 112.522 135.608 1.00 34.45  ? 179  PRO B CG    1 
ATOM   8190  C  CD    . PRO B 2 164  ? 121.244 112.249 135.929 1.00 34.45  ? 179  PRO B CD    1 
ATOM   8191  N  N     . PHE B 2 165  ? 123.174 113.175 140.054 1.00 30.93  ? 180  PHE B N     1 
ATOM   8192  C  CA    . PHE B 2 165  ? 123.069 114.123 141.154 1.00 30.93  ? 180  PHE B CA    1 
ATOM   8193  C  C     . PHE B 2 165  ? 124.481 114.474 141.601 1.00 30.93  ? 180  PHE B C     1 
ATOM   8194  O  O     . PHE B 2 165  ? 125.467 113.976 141.053 1.00 30.93  ? 180  PHE B O     1 
ATOM   8195  C  CB    . PHE B 2 165  ? 122.234 113.563 142.307 1.00 30.93  ? 180  PHE B CB    1 
ATOM   8196  C  CG    . PHE B 2 165  ? 122.822 112.342 142.950 1.00 30.93  ? 180  PHE B CG    1 
ATOM   8197  C  CD1   . PHE B 2 165  ? 122.532 111.081 142.462 1.00 30.93  ? 180  PHE B CD1   1 
ATOM   8198  C  CD2   . PHE B 2 165  ? 123.648 112.453 144.055 1.00 30.93  ? 180  PHE B CD2   1 
ATOM   8199  C  CE1   . PHE B 2 165  ? 123.061 109.956 143.055 1.00 30.93  ? 180  PHE B CE1   1 
ATOM   8200  C  CE2   . PHE B 2 165  ? 124.181 111.331 144.652 1.00 30.93  ? 180  PHE B CE2   1 
ATOM   8201  C  CZ    . PHE B 2 165  ? 123.887 110.081 144.151 1.00 30.93  ? 180  PHE B CZ    1 
ATOM   8202  N  N     . GLY B 2 166  ? 124.573 115.338 142.608 1.00 26.87  ? 181  GLY B N     1 
ATOM   8203  C  CA    . GLY B 2 166  ? 125.860 115.776 143.103 1.00 26.87  ? 181  GLY B CA    1 
ATOM   8204  C  C     . GLY B 2 166  ? 125.842 115.929 144.609 1.00 26.87  ? 181  GLY B C     1 
ATOM   8205  O  O     . GLY B 2 166  ? 124.789 116.072 145.233 1.00 26.87  ? 181  GLY B O     1 
ATOM   8206  N  N     . LEU B 2 167  ? 127.043 115.894 145.186 1.00 22.13  ? 182  LEU B N     1 
ATOM   8207  C  CA    . LEU B 2 167  ? 127.242 116.050 146.628 1.00 22.13  ? 182  LEU B CA    1 
ATOM   8208  C  C     . LEU B 2 167  ? 128.390 117.039 146.807 1.00 22.13  ? 182  LEU B C     1 
ATOM   8209  O  O     . LEU B 2 167  ? 129.553 116.642 146.896 1.00 22.13  ? 182  LEU B O     1 
ATOM   8210  C  CB    . LEU B 2 167  ? 127.539 114.714 147.291 1.00 22.13  ? 182  LEU B CB    1 
ATOM   8211  C  CG    . LEU B 2 167  ? 126.453 113.644 147.214 1.00 22.13  ? 182  LEU B CG    1 
ATOM   8212  C  CD1   . LEU B 2 167  ? 127.002 112.296 147.637 1.00 22.13  ? 182  LEU B CD1   1 
ATOM   8213  C  CD2   . LEU B 2 167  ? 125.277 114.033 148.083 1.00 22.13  ? 182  LEU B CD2   1 
ATOM   8214  N  N     . ALA B 2 168  ? 128.056 118.322 146.865 1.00 17.68  ? 183  ALA B N     1 
ATOM   8215  C  CA    . ALA B 2 168  ? 129.059 119.372 146.940 1.00 17.68  ? 183  ALA B CA    1 
ATOM   8216  C  C     . ALA B 2 168  ? 129.391 119.696 148.388 1.00 17.68  ? 183  ALA B C     1 
ATOM   8217  O  O     . ALA B 2 168  ? 128.551 119.574 149.283 1.00 17.68  ? 183  ALA B O     1 
ATOM   8218  C  CB    . ALA B 2 168  ? 128.579 120.633 146.222 1.00 17.68  ? 183  ALA B CB    1 
ATOM   8219  N  N     . GLN B 2 169  ? 130.631 120.117 148.610 1.00 17.88  ? 184  GLN B N     1 
ATOM   8220  C  CA    . GLN B 2 169  ? 131.103 120.389 149.957 1.00 17.88  ? 184  GLN B CA    1 
ATOM   8221  C  C     . GLN B 2 169  ? 132.317 121.297 149.882 1.00 17.88  ? 184  GLN B C     1 
ATOM   8222  O  O     . GLN B 2 169  ? 133.099 121.234 148.932 1.00 17.88  ? 184  GLN B O     1 
ATOM   8223  C  CB    . GLN B 2 169  ? 131.449 119.091 150.692 1.00 17.88  ? 184  GLN B CB    1 
ATOM   8224  C  CG    . GLN B 2 169  ? 131.875 119.266 152.134 1.00 17.88  ? 184  GLN B CG    1 
ATOM   8225  C  CD    . GLN B 2 169  ? 132.219 117.949 152.788 1.00 17.88  ? 184  GLN B CD    1 
ATOM   8226  O  OE1   . GLN B 2 169  ? 132.482 117.888 153.987 1.00 17.88  ? 184  GLN B OE1   1 
ATOM   8227  N  NE2   . GLN B 2 169  ? 132.222 116.883 151.999 1.00 17.88  ? 184  GLN B NE2   1 
ATOM   8228  N  N     . ILE B 2 170  ? 132.459 122.143 150.894 1.00 15.94  ? 185  ILE B N     1 
ATOM   8229  C  CA    . ILE B 2 170  ? 133.634 122.982 151.072 1.00 15.94  ? 185  ILE B CA    1 
ATOM   8230  C  C     . ILE B 2 170  ? 134.192 122.701 152.459 1.00 15.94  ? 185  ILE B C     1 
ATOM   8231  O  O     . ILE B 2 170  ? 133.446 122.703 153.444 1.00 15.94  ? 185  ILE B O     1 
ATOM   8232  C  CB    . ILE B 2 170  ? 133.301 124.473 150.897 1.00 15.94  ? 185  ILE B CB    1 
ATOM   8233  C  CG1   . ILE B 2 170  ? 132.728 124.719 149.501 1.00 15.94  ? 185  ILE B CG1   1 
ATOM   8234  C  CG2   . ILE B 2 170  ? 134.531 125.327 151.139 1.00 15.94  ? 185  ILE B CG2   1 
ATOM   8235  C  CD1   . ILE B 2 170  ? 132.421 126.160 149.209 1.00 15.94  ? 185  ILE B CD1   1 
ATOM   8236  N  N     . GLY B 2 171  ? 135.490 122.447 152.531 1.00 21.56  ? 186  GLY B N     1 
ATOM   8237  C  CA    . GLY B 2 171  ? 136.095 122.085 153.794 1.00 21.56  ? 186  GLY B CA    1 
ATOM   8238  C  C     . GLY B 2 171  ? 137.601 122.138 153.703 1.00 21.56  ? 186  GLY B C     1 
ATOM   8239  O  O     . GLY B 2 171  ? 138.168 122.534 152.684 1.00 21.56  ? 186  GLY B O     1 
ATOM   8240  N  N     . VAL B 2 172  ? 138.246 121.725 154.789 1.00 32.07  ? 187  VAL B N     1 
ATOM   8241  C  CA    . VAL B 2 172  ? 139.697 121.769 154.908 1.00 32.07  ? 187  VAL B CA    1 
ATOM   8242  C  C     . VAL B 2 172  ? 140.250 120.371 154.679 1.00 32.07  ? 187  VAL B C     1 
ATOM   8243  O  O     . VAL B 2 172  ? 139.750 119.395 155.254 1.00 32.07  ? 187  VAL B O     1 
ATOM   8244  C  CB    . VAL B 2 172  ? 140.125 122.315 156.280 1.00 32.07  ? 187  VAL B CB    1 
ATOM   8245  C  CG1   . VAL B 2 172  ? 141.636 122.408 156.365 1.00 32.07  ? 187  VAL B CG1   1 
ATOM   8246  C  CG2   . VAL B 2 172  ? 139.490 123.672 156.527 1.00 32.07  ? 187  VAL B CG2   1 
ATOM   8247  N  N     . CYS B 2 173  ? 141.268 120.271 153.829 1.00 37.59  ? 188  CYS B N     1 
ATOM   8248  C  CA    . CYS B 2 173  ? 141.970 119.024 153.573 1.00 37.59  ? 188  CYS B CA    1 
ATOM   8249  C  C     . CYS B 2 173  ? 143.435 119.192 153.945 1.00 37.59  ? 188  CYS B C     1 
ATOM   8250  O  O     . CYS B 2 173  ? 144.005 120.278 153.808 1.00 37.59  ? 188  CYS B O     1 
ATOM   8251  C  CB    . CYS B 2 173  ? 141.843 118.600 152.110 1.00 37.59  ? 188  CYS B CB    1 
ATOM   8252  S  SG    . CYS B 2 173  ? 140.170 118.155 151.625 1.00 37.59  ? 188  CYS B SG    1 
ATOM   8253  N  N     . PHE B 2 174  ? 144.042 118.107 154.416 1.00 41.54  ? 189  PHE B N     1 
ATOM   8254  C  CA    . PHE B 2 174  ? 145.387 118.135 154.973 1.00 41.54  ? 189  PHE B CA    1 
ATOM   8255  C  C     . PHE B 2 174  ? 146.364 117.513 153.986 1.00 41.54  ? 189  PHE B C     1 
ATOM   8256  O  O     . PHE B 2 174  ? 146.143 116.397 153.505 1.00 41.54  ? 189  PHE B O     1 
ATOM   8257  C  CB    . PHE B 2 174  ? 145.429 117.394 156.312 1.00 41.54  ? 189  PHE B CB    1 
ATOM   8258  C  CG    . PHE B 2 174  ? 144.364 117.830 157.280 1.00 41.54  ? 189  PHE B CG    1 
ATOM   8259  C  CD1   . PHE B 2 174  ? 143.124 117.217 157.288 1.00 41.54  ? 189  PHE B CD1   1 
ATOM   8260  C  CD2   . PHE B 2 174  ? 144.602 118.852 158.180 1.00 41.54  ? 189  PHE B CD2   1 
ATOM   8261  C  CE1   . PHE B 2 174  ? 142.143 117.616 158.173 1.00 41.54  ? 189  PHE B CE1   1 
ATOM   8262  C  CE2   . PHE B 2 174  ? 143.624 119.254 159.067 1.00 41.54  ? 189  PHE B CE2   1 
ATOM   8263  C  CZ    . PHE B 2 174  ? 142.394 118.635 159.063 1.00 41.54  ? 189  PHE B CZ    1 
ATOM   8264  N  N     . HIS B 2 175  ? 147.443 118.236 153.691 1.00 49.59  ? 190  HIS B N     1 
ATOM   8265  C  CA    . HIS B 2 175  ? 148.420 117.827 152.699 1.00 49.59  ? 190  HIS B CA    1 
ATOM   8266  C  C     . HIS B 2 175  ? 149.790 117.664 153.341 1.00 49.59  ? 190  HIS B C     1 
ATOM   8267  O  O     . HIS B 2 175  ? 150.268 118.594 154.007 1.00 49.59  ? 190  HIS B O     1 
ATOM   8268  C  CB    . HIS B 2 175  ? 148.512 118.859 151.565 1.00 49.59  ? 190  HIS B CB    1 
ATOM   8269  C  CG    . HIS B 2 175  ? 147.241 119.030 150.797 1.00 49.59  ? 190  HIS B CG    1 
ATOM   8270  N  ND1   . HIS B 2 175  ? 146.380 117.985 150.540 1.00 49.59  ? 190  HIS B ND1   1 
ATOM   8271  C  CD2   . HIS B 2 175  ? 146.683 120.126 150.231 1.00 49.59  ? 190  HIS B CD2   1 
ATOM   8272  C  CE1   . HIS B 2 175  ? 145.347 118.429 149.846 1.00 49.59  ? 190  HIS B CE1   1 
ATOM   8273  N  NE2   . HIS B 2 175  ? 145.506 119.725 149.646 1.00 49.59  ? 190  HIS B NE2   1 
ATOM   8274  N  N     . PRO B 2 176  ? 150.446 116.515 153.183 1.00 50.94  ? 191  PRO B N     1 
ATOM   8275  C  CA    . PRO B 2 176  ? 151.856 116.422 153.574 1.00 50.94  ? 191  PRO B CA    1 
ATOM   8276  C  C     . PRO B 2 176  ? 152.700 117.384 152.753 1.00 50.94  ? 191  PRO B C     1 
ATOM   8277  O  O     . PRO B 2 176  ? 152.490 117.552 151.551 1.00 50.94  ? 191  PRO B O     1 
ATOM   8278  C  CB    . PRO B 2 176  ? 152.214 114.962 153.278 1.00 50.94  ? 191  PRO B CB    1 
ATOM   8279  C  CG    . PRO B 2 176  ? 150.907 114.242 153.266 1.00 50.94  ? 191  PRO B CG    1 
ATOM   8280  C  CD    . PRO B 2 176  ? 149.911 115.222 152.727 1.00 50.94  ? 191  PRO B CD    1 
ATOM   8281  N  N     . VAL B 2 177  ? 153.662 118.020 153.412 1.00 57.30  ? 192  VAL B N     1 
ATOM   8282  C  CA    . VAL B 2 177  ? 154.524 118.986 152.740 1.00 57.30  ? 192  VAL B CA    1 
ATOM   8283  C  C     . VAL B 2 177  ? 155.987 118.590 152.901 1.00 57.30  ? 192  VAL B C     1 
ATOM   8284  O  O     . VAL B 2 177  ? 156.678 119.076 153.797 1.00 57.30  ? 192  VAL B O     1 
ATOM   8285  C  CB    . VAL B 2 177  ? 154.289 120.414 153.267 1.00 57.30  ? 192  VAL B CB    1 
ATOM   8286  C  CG1   . VAL B 2 177  ? 155.017 121.426 152.396 1.00 57.30  ? 192  VAL B CG1   1 
ATOM   8287  C  CG2   . VAL B 2 177  ? 152.805 120.727 153.324 1.00 57.30  ? 192  VAL B CG2   1 
ATOM   8288  N  N     . THR B 2 188  ? 157.792 115.150 158.228 1.00 64.73  ? 203  THR B N     1 
ATOM   8289  C  CA    . THR B 2 188  ? 157.106 115.963 157.232 1.00 64.73  ? 203  THR B CA    1 
ATOM   8290  C  C     . THR B 2 188  ? 156.108 116.906 157.893 1.00 64.73  ? 203  THR B C     1 
ATOM   8291  O  O     . THR B 2 188  ? 155.401 116.519 158.824 1.00 64.73  ? 203  THR B O     1 
ATOM   8292  C  CB    . THR B 2 188  ? 156.365 115.091 156.202 1.00 64.73  ? 203  THR B CB    1 
ATOM   8293  O  OG1   . THR B 2 188  ? 155.363 114.311 156.867 1.00 64.73  ? 203  THR B OG1   1 
ATOM   8294  C  CG2   . THR B 2 188  ? 157.335 114.160 155.496 1.00 64.73  ? 203  THR B CG2   1 
ATOM   8295  N  N     . ARG B 2 189  ? 156.054 118.143 157.408 1.00 63.62  ? 204  ARG B N     1 
ATOM   8296  C  CA    . ARG B 2 189  ? 155.112 119.114 157.938 1.00 63.62  ? 204  ARG B CA    1 
ATOM   8297  C  C     . ARG B 2 189  ? 153.699 118.811 157.441 1.00 63.62  ? 204  ARG B C     1 
ATOM   8298  O  O     . ARG B 2 189  ? 153.476 117.942 156.594 1.00 63.62  ? 204  ARG B O     1 
ATOM   8299  C  CB    . ARG B 2 189  ? 155.521 120.532 157.546 1.00 63.62  ? 204  ARG B CB    1 
ATOM   8300  C  CG    . ARG B 2 189  ? 156.805 121.003 158.199 1.00 63.62  ? 204  ARG B CG    1 
ATOM   8301  C  CD    . ARG B 2 189  ? 157.017 122.489 157.980 1.00 63.62  ? 204  ARG B CD    1 
ATOM   8302  N  NE    . ARG B 2 189  ? 157.161 122.819 156.568 1.00 63.62  ? 204  ARG B NE    1 
ATOM   8303  C  CZ    . ARG B 2 189  ? 157.375 124.043 156.105 1.00 63.62  ? 204  ARG B CZ    1 
ATOM   8304  N  NH1   . ARG B 2 189  ? 157.470 125.082 156.917 1.00 63.62  ? 204  ARG B NH1   1 
ATOM   8305  N  NH2   . ARG B 2 189  ? 157.499 124.228 154.793 1.00 63.62  ? 204  ARG B NH2   1 
ATOM   8306  N  N     . VAL B 2 190  ? 152.734 119.545 157.985 1.00 52.52  ? 205  VAL B N     1 
ATOM   8307  C  CA    . VAL B 2 190  ? 151.329 119.384 157.635 1.00 52.52  ? 205  VAL B CA    1 
ATOM   8308  C  C     . VAL B 2 190  ? 150.855 120.677 156.988 1.00 52.52  ? 205  VAL B C     1 
ATOM   8309  O  O     . VAL B 2 190  ? 150.975 121.758 157.577 1.00 52.52  ? 205  VAL B O     1 
ATOM   8310  C  CB    . VAL B 2 190  ? 150.472 119.037 158.861 1.00 52.52  ? 205  VAL B CB    1 
ATOM   8311  C  CG1   . VAL B 2 190  ? 149.099 118.547 158.427 1.00 52.52  ? 205  VAL B CG1   1 
ATOM   8312  C  CG2   . VAL B 2 190  ? 151.172 118.001 159.723 1.00 52.52  ? 205  VAL B CG2   1 
ATOM   8313  N  N     . GLY B 2 191  ? 150.324 120.567 155.775 1.00 46.40  ? 206  GLY B N     1 
ATOM   8314  C  CA    . GLY B 2 191  ? 149.730 121.690 155.078 1.00 46.40  ? 206  GLY B CA    1 
ATOM   8315  C  C     . GLY B 2 191  ? 148.239 121.464 154.927 1.00 46.40  ? 206  GLY B C     1 
ATOM   8316  O  O     . GLY B 2 191  ? 147.781 120.327 154.801 1.00 46.40  ? 206  GLY B O     1 
ATOM   8317  N  N     . GLU B 2 192  ? 147.479 122.553 154.946 1.00 39.94  ? 207  GLU B N     1 
ATOM   8318  C  CA    . GLU B 2 192  ? 146.032 122.476 154.849 1.00 39.94  ? 207  GLU B CA    1 
ATOM   8319  C  C     . GLU B 2 192  ? 145.544 123.389 153.739 1.00 39.94  ? 207  GLU B C     1 
ATOM   8320  O  O     . GLU B 2 192  ? 146.002 124.528 153.612 1.00 39.94  ? 207  GLU B O     1 
ATOM   8321  C  CB    . GLU B 2 192  ? 145.367 122.854 156.168 1.00 39.94  ? 207  GLU B CB    1 
ATOM   8322  C  CG    . GLU B 2 192  ? 145.818 122.004 157.332 1.00 39.94  ? 207  GLU B CG    1 
ATOM   8323  C  CD    . GLU B 2 192  ? 145.041 122.294 158.589 1.00 39.94  ? 207  GLU B CD    1 
ATOM   8324  O  OE1   . GLU B 2 192  ? 144.067 123.070 158.516 1.00 39.94  ? 207  GLU B OE1   1 
ATOM   8325  O  OE2   . GLU B 2 192  ? 145.404 121.748 159.650 1.00 39.94  ? 207  GLU B OE2   1 
ATOM   8326  N  N     . LYS B 2 193  ? 144.615 122.879 152.940 1.00 32.35  ? 208  LYS B N     1 
ATOM   8327  C  CA    . LYS B 2 193  ? 144.024 123.633 151.849 1.00 32.35  ? 208  LYS B CA    1 
ATOM   8328  C  C     . LYS B 2 193  ? 142.514 123.475 151.888 1.00 32.35  ? 208  LYS B C     1 
ATOM   8329  O  O     . LYS B 2 193  ? 142.002 122.402 152.220 1.00 32.35  ? 208  LYS B O     1 
ATOM   8330  C  CB    . LYS B 2 193  ? 144.571 123.178 150.498 1.00 32.35  ? 208  LYS B CB    1 
ATOM   8331  C  CG    . LYS B 2 193  ? 145.904 123.807 150.146 1.00 32.35  ? 208  LYS B CG    1 
ATOM   8332  C  CD    . LYS B 2 193  ? 146.406 123.309 148.809 1.00 32.35  ? 208  LYS B CD    1 
ATOM   8333  C  CE    . LYS B 2 193  ? 147.541 124.169 148.292 1.00 32.35  ? 208  LYS B CE    1 
ATOM   8334  N  NZ    . LYS B 2 193  ? 148.077 123.639 147.011 1.00 32.35  ? 208  LYS B NZ    1 
ATOM   8335  N  N     . THR B 2 194  ? 141.807 124.550 151.553 1.00 22.32  ? 209  THR B N     1 
ATOM   8336  C  CA    . THR B 2 194  ? 140.349 124.558 151.563 1.00 22.32  ? 209  THR B CA    1 
ATOM   8337  C  C     . THR B 2 194  ? 139.859 124.093 150.198 1.00 22.32  ? 209  THR B C     1 
ATOM   8338  O  O     . THR B 2 194  ? 139.950 124.829 149.211 1.00 22.32  ? 209  THR B O     1 
ATOM   8339  C  CB    . THR B 2 194  ? 139.816 125.947 151.899 1.00 22.32  ? 209  THR B CB    1 
ATOM   8340  O  OG1   . THR B 2 194  ? 140.590 126.512 152.963 1.00 22.32  ? 209  THR B OG1   1 
ATOM   8341  C  CG2   . THR B 2 194  ? 138.362 125.864 152.335 1.00 22.32  ? 209  THR B CG2   1 
ATOM   8342  N  N     . GLU B 2 195  ? 139.341 122.873 150.142 1.00 19.53  ? 210  GLU B N     1 
ATOM   8343  C  CA    . GLU B 2 195  ? 138.937 122.251 148.892 1.00 19.53  ? 210  GLU B CA    1 
ATOM   8344  C  C     . GLU B 2 195  ? 137.423 122.285 148.761 1.00 19.53  ? 210  GLU B C     1 
ATOM   8345  O  O     . GLU B 2 195  ? 136.705 121.945 149.705 1.00 19.53  ? 210  GLU B O     1 
ATOM   8346  C  CB    . GLU B 2 195  ? 139.443 120.811 148.819 1.00 19.53  ? 210  GLU B CB    1 
ATOM   8347  C  CG    . GLU B 2 195  ? 138.934 120.039 147.624 1.00 19.53  ? 210  GLU B CG    1 
ATOM   8348  C  CD    . GLU B 2 195  ? 139.472 118.630 147.579 1.00 19.53  ? 210  GLU B CD    1 
ATOM   8349  O  OE1   . GLU B 2 195  ? 140.528 118.380 148.196 1.00 19.53  ? 210  GLU B OE1   1 
ATOM   8350  O  OE2   . GLU B 2 195  ? 138.838 117.772 146.933 1.00 19.53  ? 210  GLU B OE2   1 
ATOM   8351  N  N     . ALA B 2 196  ? 136.945 122.710 147.598 1.00 15.42  ? 211  ALA B N     1 
ATOM   8352  C  CA    . ALA B 2 196  ? 135.527 122.692 147.267 1.00 15.42  ? 211  ALA B CA    1 
ATOM   8353  C  C     . ALA B 2 196  ? 135.311 121.580 146.254 1.00 15.42  ? 211  ALA B C     1 
ATOM   8354  O  O     . ALA B 2 196  ? 135.670 121.725 145.082 1.00 15.42  ? 211  ALA B O     1 
ATOM   8355  C  CB    . ALA B 2 196  ? 135.075 124.039 146.714 1.00 15.42  ? 211  ALA B CB    1 
ATOM   8356  N  N     . SER B 2 197  ? 134.726 120.477 146.700 1.00 15.78  ? 212  SER B N     1 
ATOM   8357  C  CA    . SER B 2 197  ? 134.603 119.278 145.886 1.00 15.78  ? 212  SER B CA    1 
ATOM   8358  C  C     . SER B 2 197  ? 133.153 119.055 145.488 1.00 15.78  ? 212  SER B C     1 
ATOM   8359  O  O     . SER B 2 197  ? 132.257 119.108 146.335 1.00 15.78  ? 212  SER B O     1 
ATOM   8360  C  CB    . SER B 2 197  ? 135.121 118.052 146.637 1.00 15.78  ? 212  SER B CB    1 
ATOM   8361  O  OG    . SER B 2 197  ? 134.150 117.590 147.559 1.00 15.78  ? 212  SER B OG    1 
ATOM   8362  N  N     . LEU B 2 198  ? 132.930 118.800 144.204 1.00 18.56  ? 213  LEU B N     1 
ATOM   8363  C  CA    . LEU B 2 198  ? 131.661 118.291 143.705 1.00 18.56  ? 213  LEU B CA    1 
ATOM   8364  C  C     . LEU B 2 198  ? 131.882 116.868 143.222 1.00 18.56  ? 213  LEU B C     1 
ATOM   8365  O  O     . LEU B 2 198  ? 132.644 116.643 142.278 1.00 18.56  ? 213  LEU B O     1 
ATOM   8366  C  CB    . LEU B 2 198  ? 131.110 119.152 142.570 1.00 18.56  ? 213  LEU B CB    1 
ATOM   8367  C  CG    . LEU B 2 198  ? 129.924 118.511 141.841 1.00 18.56  ? 213  LEU B CG    1 
ATOM   8368  C  CD1   . LEU B 2 198  ? 128.612 118.827 142.541 1.00 18.56  ? 213  LEU B CD1   1 
ATOM   8369  C  CD2   . LEU B 2 198  ? 129.881 118.923 140.381 1.00 18.56  ? 213  LEU B CD2   1 
ATOM   8370  N  N     . VAL B 2 199  ? 131.218 115.916 143.861 1.00 23.41  ? 214  VAL B N     1 
ATOM   8371  C  CA    . VAL B 2 199  ? 131.299 114.514 143.477 1.00 23.41  ? 214  VAL B CA    1 
ATOM   8372  C  C     . VAL B 2 199  ? 130.029 114.205 142.696 1.00 23.41  ? 214  VAL B C     1 
ATOM   8373  O  O     . VAL B 2 199  ? 128.952 114.029 143.271 1.00 23.41  ? 214  VAL B O     1 
ATOM   8374  C  CB    . VAL B 2 199  ? 131.475 113.602 144.691 1.00 23.41  ? 214  VAL B CB    1 
ATOM   8375  C  CG1   . VAL B 2 199  ? 131.311 112.153 144.287 1.00 23.41  ? 214  VAL B CG1   1 
ATOM   8376  C  CG2   . VAL B 2 199  ? 132.846 113.829 145.300 1.00 23.41  ? 214  VAL B CG2   1 
ATOM   8377  N  N     . TRP B 2 200  ? 130.159 114.141 141.377 1.00 27.19  ? 215  TRP B N     1 
ATOM   8378  C  CA    . TRP B 2 200  ? 129.017 114.047 140.482 1.00 27.19  ? 215  TRP B CA    1 
ATOM   8379  C  C     . TRP B 2 200  ? 128.874 112.612 139.990 1.00 27.19  ? 215  TRP B C     1 
ATOM   8380  O  O     . TRP B 2 200  ? 129.817 112.048 139.427 1.00 27.19  ? 215  TRP B O     1 
ATOM   8381  C  CB    . TRP B 2 200  ? 129.199 115.019 139.318 1.00 27.19  ? 215  TRP B CB    1 
ATOM   8382  C  CG    . TRP B 2 200  ? 128.045 115.086 138.389 1.00 27.19  ? 215  TRP B CG    1 
ATOM   8383  C  CD1   . TRP B 2 200  ? 127.948 114.496 137.174 1.00 27.19  ? 215  TRP B CD1   1 
ATOM   8384  C  CD2   . TRP B 2 200  ? 126.820 115.795 138.591 1.00 27.19  ? 215  TRP B CD2   1 
ATOM   8385  N  NE1   . TRP B 2 200  ? 126.736 114.784 136.599 1.00 27.19  ? 215  TRP B NE1   1 
ATOM   8386  C  CE2   . TRP B 2 200  ? 126.023 115.582 137.453 1.00 27.19  ? 215  TRP B CE2   1 
ATOM   8387  C  CE3   . TRP B 2 200  ? 126.319 116.587 139.626 1.00 27.19  ? 215  TRP B CE3   1 
ATOM   8388  C  CZ2   . TRP B 2 200  ? 124.753 116.130 137.318 1.00 27.19  ? 215  TRP B CZ2   1 
ATOM   8389  C  CZ3   . TRP B 2 200  ? 125.059 117.129 139.492 1.00 27.19  ? 215  TRP B CZ3   1 
ATOM   8390  C  CH2   . TRP B 2 200  ? 124.290 116.900 138.347 1.00 27.19  ? 215  TRP B CH2   1 
ATOM   8391  N  N     . PHE B 2 201  ? 127.702 112.025 140.208 1.00 31.83  ? 216  PHE B N     1 
ATOM   8392  C  CA    . PHE B 2 201  ? 127.432 110.642 139.840 1.00 31.83  ? 216  PHE B CA    1 
ATOM   8393  C  C     . PHE B 2 201  ? 126.630 110.606 138.546 1.00 31.83  ? 216  PHE B C     1 
ATOM   8394  O  O     . PHE B 2 201  ? 125.648 111.339 138.401 1.00 31.83  ? 216  PHE B O     1 
ATOM   8395  C  CB    . PHE B 2 201  ? 126.665 109.921 140.948 1.00 31.83  ? 216  PHE B CB    1 
ATOM   8396  C  CG    . PHE B 2 201  ? 127.378 109.893 142.268 1.00 31.83  ? 216  PHE B CG    1 
ATOM   8397  C  CD1   . PHE B 2 201  ? 127.317 110.976 143.128 1.00 31.83  ? 216  PHE B CD1   1 
ATOM   8398  C  CD2   . PHE B 2 201  ? 128.092 108.775 142.661 1.00 31.83  ? 216  PHE B CD2   1 
ATOM   8399  C  CE1   . PHE B 2 201  ? 127.964 110.949 144.346 1.00 31.83  ? 216  PHE B CE1   1 
ATOM   8400  C  CE2   . PHE B 2 201  ? 128.740 108.743 143.880 1.00 31.83  ? 216  PHE B CE2   1 
ATOM   8401  C  CZ    . PHE B 2 201  ? 128.675 109.831 144.722 1.00 31.83  ? 216  PHE B CZ    1 
ATOM   8402  N  N     . THR B 2 202  ? 127.048 109.756 137.614 1.00 31.76  ? 217  THR B N     1 
ATOM   8403  C  CA    . THR B 2 202  ? 126.421 109.650 136.305 1.00 31.76  ? 217  THR B CA    1 
ATOM   8404  C  C     . THR B 2 202  ? 126.274 108.182 135.952 1.00 31.76  ? 217  THR B C     1 
ATOM   8405  O  O     . THR B 2 202  ? 126.997 107.335 136.490 1.00 31.76  ? 217  THR B O     1 
ATOM   8406  C  CB    . THR B 2 202  ? 127.250 110.346 135.218 1.00 31.76  ? 217  THR B CB    1 
ATOM   8407  O  OG1   . THR B 2 202  ? 128.576 109.806 135.210 1.00 31.76  ? 217  THR B OG1   1 
ATOM   8408  C  CG2   . THR B 2 202  ? 127.322 111.820 135.463 1.00 31.76  ? 217  THR B CG2   1 
ATOM   8409  N  N     . PRO B 2 203  ? 125.353 107.845 135.052 1.00 35.29  ? 218  PRO B N     1 
ATOM   8410  C  CA    . PRO B 2 203  ? 125.421 106.536 134.399 1.00 35.29  ? 218  PRO B CA    1 
ATOM   8411  C  C     . PRO B 2 203  ? 126.700 106.435 133.583 1.00 35.29  ? 218  PRO B C     1 
ATOM   8412  O  O     . PRO B 2 203  ? 127.279 107.443 133.172 1.00 35.29  ? 218  PRO B O     1 
ATOM   8413  C  CB    . PRO B 2 203  ? 124.175 106.514 133.508 1.00 35.29  ? 218  PRO B CB    1 
ATOM   8414  C  CG    . PRO B 2 203  ? 123.247 107.495 134.135 1.00 35.29  ? 218  PRO B CG    1 
ATOM   8415  C  CD    . PRO B 2 203  ? 124.125 108.574 134.696 1.00 35.29  ? 218  PRO B CD    1 
ATOM   8416  N  N     . THR B 2 204  ? 127.146 105.198 133.361 1.00 38.11  ? 219  THR B N     1 
ATOM   8417  C  CA    . THR B 2 204  ? 128.456 104.980 132.756 1.00 38.11  ? 219  THR B CA    1 
ATOM   8418  C  C     . THR B 2 204  ? 128.537 105.578 131.356 1.00 38.11  ? 219  THR B C     1 
ATOM   8419  O  O     . THR B 2 204  ? 129.562 106.160 130.980 1.00 38.11  ? 219  THR B O     1 
ATOM   8420  C  CB    . THR B 2 204  ? 128.770 103.485 132.713 1.00 38.11  ? 219  THR B CB    1 
ATOM   8421  O  OG1   . THR B 2 204  ? 128.502 102.904 133.995 1.00 38.11  ? 219  THR B OG1   1 
ATOM   8422  C  CG2   . THR B 2 204  ? 130.232 103.263 132.365 1.00 38.11  ? 219  THR B CG2   1 
ATOM   8423  N  N     . ARG B 2 205  ? 127.469 105.438 130.569 1.00 37.52  ? 220  ARG B N     1 
ATOM   8424  C  CA    . ARG B 2 205  ? 127.496 105.879 129.177 1.00 37.52  ? 220  ARG B CA    1 
ATOM   8425  C  C     . ARG B 2 205  ? 127.692 107.388 129.061 1.00 37.52  ? 220  ARG B C     1 
ATOM   8426  O  O     . ARG B 2 205  ? 128.450 107.857 128.205 1.00 37.52  ? 220  ARG B O     1 
ATOM   8427  C  CB    . ARG B 2 205  ? 126.207 105.449 128.477 1.00 37.52  ? 220  ARG B CB    1 
ATOM   8428  C  CG    . ARG B 2 205  ? 124.945 105.824 129.239 1.00 37.52  ? 220  ARG B CG    1 
ATOM   8429  C  CD    . ARG B 2 205  ? 123.690 105.398 128.502 1.00 37.52  ? 220  ARG B CD    1 
ATOM   8430  N  NE    . ARG B 2 205  ? 122.489 105.912 129.150 1.00 37.52  ? 220  ARG B NE    1 
ATOM   8431  C  CZ    . ARG B 2 205  ? 121.909 107.064 128.844 1.00 37.52  ? 220  ARG B CZ    1 
ATOM   8432  N  NH1   . ARG B 2 205  ? 122.386 107.844 127.888 1.00 37.52  ? 220  ARG B NH1   1 
ATOM   8433  N  NH2   . ARG B 2 205  ? 120.822 107.441 129.510 1.00 37.52  ? 220  ARG B NH2   1 
ATOM   8434  N  N     . THR B 2 206  ? 127.018 108.162 129.906 1.00 32.21  ? 221  THR B N     1 
ATOM   8435  C  CA    . THR B 2 206  ? 127.009 109.615 129.805 1.00 32.21  ? 221  THR B CA    1 
ATOM   8436  C  C     . THR B 2 206  ? 128.198 110.272 130.489 1.00 32.21  ? 221  THR B C     1 
ATOM   8437  O  O     . THR B 2 206  ? 128.280 111.505 130.502 1.00 32.21  ? 221  THR B O     1 
ATOM   8438  C  CB    . THR B 2 206  ? 125.714 110.175 130.400 1.00 32.21  ? 221  THR B CB    1 
ATOM   8439  O  OG1   . THR B 2 206  ? 125.699 109.940 131.813 1.00 32.21  ? 221  THR B OG1   1 
ATOM   8440  C  CG2   . THR B 2 206  ? 124.509 109.499 129.776 1.00 32.21  ? 221  THR B CG2   1 
ATOM   8441  N  N     . SER B 2 207  ? 129.111 109.483 131.058 1.00 30.11  ? 222  SER B N     1 
ATOM   8442  C  CA    . SER B 2 207  ? 130.169 110.043 131.893 1.00 30.11  ? 222  SER B CA    1 
ATOM   8443  C  C     . SER B 2 207  ? 131.048 111.016 131.118 1.00 30.11  ? 222  SER B C     1 
ATOM   8444  O  O     . SER B 2 207  ? 131.416 112.076 131.636 1.00 30.11  ? 222  SER B O     1 
ATOM   8445  C  CB    . SER B 2 207  ? 131.008 108.912 132.484 1.00 30.11  ? 222  SER B CB    1 
ATOM   8446  O  OG    . SER B 2 207  ? 131.220 107.883 131.534 1.00 30.11  ? 222  SER B OG    1 
ATOM   8447  N  N     . SER B 2 208  ? 131.401 110.676 129.878 1.00 29.45  ? 223  SER B N     1 
ATOM   8448  C  CA    . SER B 2 208  ? 132.249 111.566 129.091 1.00 29.45  ? 223  SER B CA    1 
ATOM   8449  C  C     . SER B 2 208  ? 131.549 112.889 128.803 1.00 29.45  ? 223  SER B C     1 
ATOM   8450  O  O     . SER B 2 208  ? 132.150 113.962 128.939 1.00 29.45  ? 223  SER B O     1 
ATOM   8451  C  CB    . SER B 2 208  ? 132.658 110.881 127.789 1.00 29.45  ? 223  SER B CB    1 
ATOM   8452  O  OG    . SER B 2 208  ? 133.566 111.687 127.060 1.00 29.45  ? 223  SER B OG    1 
ATOM   8453  N  N     . GLN B 2 209  ? 130.275 112.831 128.406 1.00 29.57  ? 224  GLN B N     1 
ATOM   8454  C  CA    . GLN B 2 209  ? 129.524 114.051 128.130 1.00 29.57  ? 224  GLN B CA    1 
ATOM   8455  C  C     . GLN B 2 209  ? 129.401 114.918 129.374 1.00 29.57  ? 224  GLN B C     1 
ATOM   8456  O  O     . GLN B 2 209  ? 129.574 116.141 129.309 1.00 29.57  ? 224  GLN B O     1 
ATOM   8457  C  CB    . GLN B 2 209  ? 128.137 113.701 127.594 1.00 29.57  ? 224  GLN B CB    1 
ATOM   8458  C  CG    . GLN B 2 209  ? 127.111 114.808 127.769 1.00 29.57  ? 224  GLN B CG    1 
ATOM   8459  C  CD    . GLN B 2 209  ? 125.751 114.272 128.161 1.00 29.57  ? 224  GLN B CD    1 
ATOM   8460  O  OE1   . GLN B 2 209  ? 125.437 113.110 127.911 1.00 29.57  ? 224  GLN B OE1   1 
ATOM   8461  N  NE2   . GLN B 2 209  ? 124.941 115.114 128.791 1.00 29.57  ? 224  GLN B NE2   1 
ATOM   8462  N  N     . TRP B 2 210  ? 129.093 114.303 130.517 1.00 25.39  ? 225  TRP B N     1 
ATOM   8463  C  CA    . TRP B 2 210  ? 128.973 115.072 131.747 1.00 25.39  ? 225  TRP B CA    1 
ATOM   8464  C  C     . TRP B 2 210  ? 130.314 115.644 132.171 1.00 25.39  ? 225  TRP B C     1 
ATOM   8465  O  O     . TRP B 2 210  ? 130.374 116.754 132.706 1.00 25.39  ? 225  TRP B O     1 
ATOM   8466  C  CB    . TRP B 2 210  ? 128.385 114.209 132.856 1.00 25.39  ? 225  TRP B CB    1 
ATOM   8467  C  CG    . TRP B 2 210  ? 126.901 114.161 132.829 1.00 25.39  ? 225  TRP B CG    1 
ATOM   8468  C  CD1   . TRP B 2 210  ? 126.123 113.093 132.504 1.00 25.39  ? 225  TRP B CD1   1 
ATOM   8469  C  CD2   . TRP B 2 210  ? 126.006 115.233 133.136 1.00 25.39  ? 225  TRP B CD2   1 
ATOM   8470  N  NE1   . TRP B 2 210  ? 124.795 113.429 132.597 1.00 25.39  ? 225  TRP B NE1   1 
ATOM   8471  C  CE2   . TRP B 2 210  ? 124.697 114.740 132.981 1.00 25.39  ? 225  TRP B CE2   1 
ATOM   8472  C  CE3   . TRP B 2 210  ? 126.184 116.562 133.528 1.00 25.39  ? 225  TRP B CE3   1 
ATOM   8473  C  CZ2   . TRP B 2 210  ? 123.573 115.527 133.205 1.00 25.39  ? 225  TRP B CZ2   1 
ATOM   8474  C  CZ3   . TRP B 2 210  ? 125.067 117.341 133.750 1.00 25.39  ? 225  TRP B CZ3   1 
ATOM   8475  C  CH2   . TRP B 2 210  ? 123.779 116.823 133.587 1.00 25.39  ? 225  TRP B CH2   1 
ATOM   8476  N  N     . LEU B 2 211  ? 131.400 114.905 131.943 1.00 24.96  ? 226  LEU B N     1 
ATOM   8477  C  CA    . LEU B 2 211  ? 132.721 115.449 132.230 1.00 24.96  ? 226  LEU B CA    1 
ATOM   8478  C  C     . LEU B 2 211  ? 133.006 116.673 131.372 1.00 24.96  ? 226  LEU B C     1 
ATOM   8479  O  O     . LEU B 2 211  ? 133.531 117.676 131.866 1.00 24.96  ? 226  LEU B O     1 
ATOM   8480  C  CB    . LEU B 2 211  ? 133.795 114.385 132.008 1.00 24.96  ? 226  LEU B CB    1 
ATOM   8481  C  CG    . LEU B 2 211  ? 135.235 114.895 132.095 1.00 24.96  ? 226  LEU B CG    1 
ATOM   8482  C  CD1   . LEU B 2 211  ? 135.519 115.449 133.478 1.00 24.96  ? 226  LEU B CD1   1 
ATOM   8483  C  CD2   . LEU B 2 211  ? 136.222 113.796 131.743 1.00 24.96  ? 226  LEU B CD2   1 
ATOM   8484  N  N     . ASP B 2 212  ? 132.660 116.611 130.085 1.00 22.79  ? 227  ASP B N     1 
ATOM   8485  C  CA    . ASP B 2 212  ? 132.862 117.764 129.213 1.00 22.79  ? 227  ASP B CA    1 
ATOM   8486  C  C     . ASP B 2 212  ? 132.025 118.952 129.668 1.00 22.79  ? 227  ASP B C     1 
ATOM   8487  O  O     . ASP B 2 212  ? 132.509 120.093 129.706 1.00 22.79  ? 227  ASP B O     1 
ATOM   8488  C  CB    . ASP B 2 212  ? 132.521 117.392 127.771 1.00 22.79  ? 227  ASP B CB    1 
ATOM   8489  C  CG    . ASP B 2 212  ? 133.324 116.207 127.269 1.00 22.79  ? 227  ASP B CG    1 
ATOM   8490  O  OD1   . ASP B 2 212  ? 134.243 115.760 127.987 1.00 22.79  ? 227  ASP B OD1   1 
ATOM   8491  O  OD2   . ASP B 2 212  ? 133.034 115.716 126.158 1.00 22.79  ? 227  ASP B OD2   1 
ATOM   8492  N  N     . PHE B 2 213  ? 130.764 118.700 130.023 1.00 21.32  ? 228  PHE B N     1 
ATOM   8493  C  CA    . PHE B 2 213  ? 129.900 119.780 130.483 1.00 21.32  ? 228  PHE B CA    1 
ATOM   8494  C  C     . PHE B 2 213  ? 130.435 120.405 131.760 1.00 21.32  ? 228  PHE B C     1 
ATOM   8495  O  O     . PHE B 2 213  ? 130.431 121.631 131.903 1.00 21.32  ? 228  PHE B O     1 
ATOM   8496  C  CB    . PHE B 2 213  ? 128.477 119.274 130.703 1.00 21.32  ? 228  PHE B CB    1 
ATOM   8497  C  CG    . PHE B 2 213  ? 127.648 120.181 131.565 1.00 21.32  ? 228  PHE B CG    1 
ATOM   8498  C  CD1   . PHE B 2 213  ? 127.333 121.460 131.142 1.00 21.32  ? 228  PHE B CD1   1 
ATOM   8499  C  CD2   . PHE B 2 213  ? 127.188 119.757 132.797 1.00 21.32  ? 228  PHE B CD2   1 
ATOM   8500  C  CE1   . PHE B 2 213  ? 126.575 122.299 131.934 1.00 21.32  ? 228  PHE B CE1   1 
ATOM   8501  C  CE2   . PHE B 2 213  ? 126.426 120.590 133.591 1.00 21.32  ? 228  PHE B CE2   1 
ATOM   8502  C  CZ    . PHE B 2 213  ? 126.120 121.863 133.159 1.00 21.32  ? 228  PHE B CZ    1 
ATOM   8503  N  N     . TRP B 2 214  ? 130.882 119.580 132.706 1.00 21.51  ? 229  TRP B N     1 
ATOM   8504  C  CA    . TRP B 2 214  ? 131.419 120.115 133.949 1.00 21.51  ? 229  TRP B CA    1 
ATOM   8505  C  C     . TRP B 2 214  ? 132.698 120.894 133.706 1.00 21.51  ? 229  TRP B C     1 
ATOM   8506  O  O     . TRP B 2 214  ? 132.910 121.941 134.319 1.00 21.51  ? 229  TRP B O     1 
ATOM   8507  C  CB    . TRP B 2 214  ? 131.654 118.994 134.957 1.00 21.51  ? 229  TRP B CB    1 
ATOM   8508  C  CG    . TRP B 2 214  ? 130.410 118.592 135.664 1.00 21.51  ? 229  TRP B CG    1 
ATOM   8509  C  CD1   . TRP B 2 214  ? 129.853 117.353 135.698 1.00 21.51  ? 229  TRP B CD1   1 
ATOM   8510  C  CD2   . TRP B 2 214  ? 129.548 119.442 136.428 1.00 21.51  ? 229  TRP B CD2   1 
ATOM   8511  N  NE1   . TRP B 2 214  ? 128.702 117.372 136.445 1.00 21.51  ? 229  TRP B NE1   1 
ATOM   8512  C  CE2   . TRP B 2 214  ? 128.493 118.644 136.905 1.00 21.51  ? 229  TRP B CE2   1 
ATOM   8513  C  CE3   . TRP B 2 214  ? 129.570 120.799 136.761 1.00 21.51  ? 229  TRP B CE3   1 
ATOM   8514  C  CZ2   . TRP B 2 214  ? 127.469 119.156 137.694 1.00 21.51  ? 229  TRP B CZ2   1 
ATOM   8515  C  CZ3   . TRP B 2 214  ? 128.554 121.305 137.543 1.00 21.51  ? 229  TRP B CZ3   1 
ATOM   8516  C  CH2   . TRP B 2 214  ? 127.517 120.485 138.002 1.00 21.51  ? 229  TRP B CH2   1 
ATOM   8517  N  N     . LEU B 2 215  ? 133.556 120.411 132.809 1.00 18.99  ? 230  LEU B N     1 
ATOM   8518  C  CA    . LEU B 2 215  ? 134.757 121.164 132.469 1.00 18.99  ? 230  LEU B CA    1 
ATOM   8519  C  C     . LEU B 2 215  ? 134.397 122.546 131.941 1.00 18.99  ? 230  LEU B C     1 
ATOM   8520  O  O     . LEU B 2 215  ? 134.916 123.563 132.422 1.00 18.99  ? 230  LEU B O     1 
ATOM   8521  C  CB    . LEU B 2 215  ? 135.583 120.392 131.442 1.00 18.99  ? 230  LEU B CB    1 
ATOM   8522  C  CG    . LEU B 2 215  ? 136.703 121.179 130.768 1.00 18.99  ? 230  LEU B CG    1 
ATOM   8523  C  CD1   . LEU B 2 215  ? 137.709 121.657 131.799 1.00 18.99  ? 230  LEU B CD1   1 
ATOM   8524  C  CD2   . LEU B 2 215  ? 137.382 120.339 129.698 1.00 18.99  ? 230  LEU B CD2   1 
ATOM   8525  N  N     . ARG B 2 216  ? 133.467 122.661 131.003 1.00 18.73  ? 231  ARG B N     1 
ATOM   8526  C  CA    . ARG B 2 216  ? 133.208 124.009 130.476 1.00 18.73  ? 231  ARG B CA    1 
ATOM   8527  C  C     . ARG B 2 216  ? 132.405 124.857 131.445 1.00 18.73  ? 231  ARG B C     1 
ATOM   8528  O  O     . ARG B 2 216  ? 132.589 126.064 131.506 1.00 18.73  ? 231  ARG B O     1 
ATOM   8529  C  CB    . ARG B 2 216  ? 132.496 124.004 129.127 1.00 18.73  ? 231  ARG B CB    1 
ATOM   8530  C  CG    . ARG B 2 216  ? 132.483 125.387 128.498 1.00 18.73  ? 231  ARG B CG    1 
ATOM   8531  C  CD    . ARG B 2 216  ? 131.529 125.514 127.325 1.00 18.73  ? 231  ARG B CD    1 
ATOM   8532  N  NE    . ARG B 2 216  ? 131.474 126.897 126.861 1.00 18.73  ? 231  ARG B NE    1 
ATOM   8533  C  CZ    . ARG B 2 216  ? 130.692 127.336 125.880 1.00 18.73  ? 231  ARG B CZ    1 
ATOM   8534  N  NH1   . ARG B 2 216  ? 129.883 126.503 125.245 1.00 18.73  ? 231  ARG B NH1   1 
ATOM   8535  N  NH2   . ARG B 2 216  ? 130.718 128.615 125.538 1.00 18.73  ? 231  ARG B NH2   1 
ATOM   8536  N  N     . HIS B 2 217  ? 131.526 124.242 132.218 1.00 18.44  ? 232  HIS B N     1 
ATOM   8537  C  CA    . HIS B 2 217  ? 130.813 125.049 133.202 1.00 18.44  ? 232  HIS B CA    1 
ATOM   8538  C  C     . HIS B 2 217  ? 131.754 125.587 134.270 1.00 18.44  ? 232  HIS B C     1 
ATOM   8539  O  O     . HIS B 2 217  ? 131.656 126.756 134.652 1.00 18.44  ? 232  HIS B O     1 
ATOM   8540  C  CB    . HIS B 2 217  ? 129.692 124.235 133.844 1.00 18.44  ? 232  HIS B CB    1 
ATOM   8541  C  CG    . HIS B 2 217  ? 129.052 124.917 135.012 1.00 18.44  ? 232  HIS B CG    1 
ATOM   8542  N  ND1   . HIS B 2 217  ? 129.075 124.392 136.286 1.00 18.44  ? 232  HIS B ND1   1 
ATOM   8543  C  CD2   . HIS B 2 217  ? 128.384 126.091 135.102 1.00 18.44  ? 232  HIS B CD2   1 
ATOM   8544  C  CE1   . HIS B 2 217  ? 128.443 125.209 137.109 1.00 18.44  ? 232  HIS B CE1   1 
ATOM   8545  N  NE2   . HIS B 2 217  ? 128.015 126.249 136.416 1.00 18.44  ? 232  HIS B NE2   1 
ATOM   8546  N  N     . ARG B 2 218  ? 132.661 124.750 134.776 1.00 15.67  ? 233  ARG B N     1 
ATOM   8547  C  CA    . ARG B 2 218  ? 133.616 125.220 135.770 1.00 15.67  ? 233  ARG B CA    1 
ATOM   8548  C  C     . ARG B 2 218  ? 134.539 126.270 135.177 1.00 15.67  ? 233  ARG B C     1 
ATOM   8549  O  O     . ARG B 2 218  ? 134.886 127.246 135.847 1.00 15.67  ? 233  ARG B O     1 
ATOM   8550  C  CB    . ARG B 2 218  ? 134.423 124.050 136.335 1.00 15.67  ? 233  ARG B CB    1 
ATOM   8551  C  CG    . ARG B 2 218  ? 133.607 123.014 137.106 1.00 15.67  ? 233  ARG B CG    1 
ATOM   8552  C  CD    . ARG B 2 218  ? 132.529 123.654 137.963 1.00 15.67  ? 233  ARG B CD    1 
ATOM   8553  N  NE    . ARG B 2 218  ? 133.071 124.607 138.922 1.00 15.67  ? 233  ARG B NE    1 
ATOM   8554  C  CZ    . ARG B 2 218  ? 132.343 125.494 139.585 1.00 15.67  ? 233  ARG B CZ    1 
ATOM   8555  N  NH1   . ARG B 2 218  ? 131.034 125.572 139.424 1.00 15.67  ? 233  ARG B NH1   1 
ATOM   8556  N  NH2   . ARG B 2 218  ? 132.946 126.330 140.424 1.00 15.67  ? 233  ARG B NH2   1 
ATOM   8557  N  N     . LEU B 2 219  ? 134.939 126.096 133.916 1.00 12.70  ? 234  LEU B N     1 
ATOM   8558  C  CA    . LEU B 2 219  ? 135.783 127.101 133.283 1.00 12.70  ? 234  LEU B CA    1 
ATOM   8559  C  C     . LEU B 2 219  ? 135.041 128.423 133.128 1.00 12.70  ? 234  LEU B C     1 
ATOM   8560  O  O     . LEU B 2 219  ? 135.613 129.495 133.355 1.00 12.70  ? 234  LEU B O     1 
ATOM   8561  C  CB    . LEU B 2 219  ? 136.278 126.591 131.933 1.00 12.70  ? 234  LEU B CB    1 
ATOM   8562  C  CG    . LEU B 2 219  ? 137.475 127.358 131.388 1.00 12.70  ? 234  LEU B CG    1 
ATOM   8563  C  CD1   . LEU B 2 219  ? 138.532 127.463 132.467 1.00 12.70  ? 234  LEU B CD1   1 
ATOM   8564  C  CD2   . LEU B 2 219  ? 138.027 126.671 130.158 1.00 12.70  ? 234  LEU B CD2   1 
ATOM   8565  N  N     . LEU B 2 220  ? 133.758 128.367 132.758 1.00 15.95  ? 235  LEU B N     1 
ATOM   8566  C  CA    . LEU B 2 220  ? 132.959 129.585 132.664 1.00 15.95  ? 235  LEU B CA    1 
ATOM   8567  C  C     . LEU B 2 220  ? 132.790 130.243 134.025 1.00 15.95  ? 235  LEU B C     1 
ATOM   8568  O  O     . LEU B 2 220  ? 132.854 131.471 134.139 1.00 15.95  ? 235  LEU B O     1 
ATOM   8569  C  CB    . LEU B 2 220  ? 131.592 129.282 132.055 1.00 15.95  ? 235  LEU B CB    1 
ATOM   8570  C  CG    . LEU B 2 220  ? 131.581 128.932 130.570 1.00 15.95  ? 235  LEU B CG    1 
ATOM   8571  C  CD1   . LEU B 2 220  ? 130.158 128.720 130.081 1.00 15.95  ? 235  LEU B CD1   1 
ATOM   8572  C  CD2   . LEU B 2 220  ? 132.276 130.017 129.766 1.00 15.95  ? 235  LEU B CD2   1 
ATOM   8573  N  N     . TRP B 2 221  ? 132.549 129.445 135.065 1.00 13.67  ? 236  TRP B N     1 
ATOM   8574  C  CA    . TRP B 2 221  ? 132.403 129.997 136.406 1.00 13.67  ? 236  TRP B CA    1 
ATOM   8575  C  C     . TRP B 2 221  ? 133.685 130.674 136.862 1.00 13.67  ? 236  TRP B C     1 
ATOM   8576  O  O     . TRP B 2 221  ? 133.651 131.773 137.425 1.00 13.67  ? 236  TRP B O     1 
ATOM   8577  C  CB    . TRP B 2 221  ? 132.004 128.893 137.383 1.00 13.67  ? 236  TRP B CB    1 
ATOM   8578  C  CG    . TRP B 2 221  ? 131.714 129.386 138.761 1.00 13.67  ? 236  TRP B CG    1 
ATOM   8579  C  CD1   . TRP B 2 221  ? 130.494 129.714 139.272 1.00 13.67  ? 236  TRP B CD1   1 
ATOM   8580  C  CD2   . TRP B 2 221  ? 132.660 129.607 139.810 1.00 13.67  ? 236  TRP B CD2   1 
ATOM   8581  N  NE1   . TRP B 2 221  ? 130.622 130.126 140.575 1.00 13.67  ? 236  TRP B NE1   1 
ATOM   8582  C  CE2   . TRP B 2 221  ? 131.944 130.069 140.928 1.00 13.67  ? 236  TRP B CE2   1 
ATOM   8583  C  CE3   . TRP B 2 221  ? 134.045 129.457 139.912 1.00 13.67  ? 236  TRP B CE3   1 
ATOM   8584  C  CZ2   . TRP B 2 221  ? 132.565 130.386 142.131 1.00 13.67  ? 236  TRP B CZ2   1 
ATOM   8585  C  CZ3   . TRP B 2 221  ? 134.657 129.771 141.105 1.00 13.67  ? 236  TRP B CZ3   1 
ATOM   8586  C  CH2   . TRP B 2 221  ? 133.919 130.228 142.199 1.00 13.67  ? 236  TRP B CH2   1 
ATOM   8587  N  N     . TRP B 2 222  ? 134.829 130.033 136.629 1.00 15.32  ? 237  TRP B N     1 
ATOM   8588  C  CA    . TRP B 2 222  ? 136.090 130.627 137.050 1.00 15.32  ? 237  TRP B CA    1 
ATOM   8589  C  C     . TRP B 2 222  ? 136.430 131.860 136.226 1.00 15.32  ? 237  TRP B C     1 
ATOM   8590  O  O     . TRP B 2 222  ? 137.038 132.798 136.749 1.00 15.32  ? 237  TRP B O     1 
ATOM   8591  C  CB    . TRP B 2 222  ? 137.212 129.590 136.977 1.00 15.32  ? 237  TRP B CB    1 
ATOM   8592  C  CG    . TRP B 2 222  ? 137.214 128.627 138.133 1.00 15.32  ? 237  TRP B CG    1 
ATOM   8593  C  CD1   . TRP B 2 222  ? 136.620 127.400 138.184 1.00 15.32  ? 237  TRP B CD1   1 
ATOM   8594  C  CD2   . TRP B 2 222  ? 137.840 128.819 139.407 1.00 15.32  ? 237  TRP B CD2   1 
ATOM   8595  N  NE1   . TRP B 2 222  ? 136.837 126.816 139.407 1.00 15.32  ? 237  TRP B NE1   1 
ATOM   8596  C  CE2   . TRP B 2 222  ? 137.584 127.668 140.176 1.00 15.32  ? 237  TRP B CE2   1 
ATOM   8597  C  CE3   . TRP B 2 222  ? 138.591 129.853 139.971 1.00 15.32  ? 237  TRP B CE3   1 
ATOM   8598  C  CZ2   . TRP B 2 222  ? 138.053 127.522 141.477 1.00 15.32  ? 237  TRP B CZ2   1 
ATOM   8599  C  CZ3   . TRP B 2 222  ? 139.054 129.706 141.258 1.00 15.32  ? 237  TRP B CZ3   1 
ATOM   8600  C  CH2   . TRP B 2 222  ? 138.784 128.551 141.999 1.00 15.32  ? 237  TRP B CH2   1 
ATOM   8601  N  N     . ARG B 2 223  ? 136.044 131.887 134.949 1.00 18.32  ? 238  ARG B N     1 
ATOM   8602  C  CA    . ARG B 2 223  ? 136.291 133.050 134.107 1.00 18.32  ? 238  ARG B CA    1 
ATOM   8603  C  C     . ARG B 2 223  ? 135.276 134.165 134.313 1.00 18.32  ? 238  ARG B C     1 
ATOM   8604  O  O     . ARG B 2 223  ? 135.518 135.289 133.862 1.00 18.32  ? 238  ARG B O     1 
ATOM   8605  C  CB    . ARG B 2 223  ? 136.292 132.638 132.635 1.00 18.32  ? 238  ARG B CB    1 
ATOM   8606  C  CG    . ARG B 2 223  ? 137.525 131.880 132.204 1.00 18.32  ? 238  ARG B CG    1 
ATOM   8607  C  CD    . ARG B 2 223  ? 137.358 131.348 130.799 1.00 18.32  ? 238  ARG B CD    1 
ATOM   8608  N  NE    . ARG B 2 223  ? 138.628 130.934 130.220 1.00 18.32  ? 238  ARG B NE    1 
ATOM   8609  C  CZ    . ARG B 2 223  ? 138.745 130.285 129.071 1.00 18.32  ? 238  ARG B CZ    1 
ATOM   8610  N  NH1   . ARG B 2 223  ? 137.684 129.948 128.358 1.00 18.32  ? 238  ARG B NH1   1 
ATOM   8611  N  NH2   . ARG B 2 223  ? 139.956 129.965 128.627 1.00 18.32  ? 238  ARG B NH2   1 
ATOM   8612  N  N     . LYS B 2 224  ? 134.152 133.876 134.971 1.00 17.80  ? 239  LYS B N     1 
ATOM   8613  C  CA    . LYS B 2 224  ? 133.102 134.871 135.154 1.00 17.80  ? 239  LYS B CA    1 
ATOM   8614  C  C     . LYS B 2 224  ? 133.597 136.054 135.975 1.00 17.80  ? 239  LYS B C     1 
ATOM   8615  O  O     . LYS B 2 224  ? 133.377 137.214 135.611 1.00 17.80  ? 239  LYS B O     1 
ATOM   8616  C  CB    . LYS B 2 224  ? 131.897 134.216 135.825 1.00 17.80  ? 239  LYS B CB    1 
ATOM   8617  C  CG    . LYS B 2 224  ? 130.783 135.169 136.190 1.00 17.80  ? 239  LYS B CG    1 
ATOM   8618  C  CD    . LYS B 2 224  ? 129.823 134.521 137.172 1.00 17.80  ? 239  LYS B CD    1 
ATOM   8619  C  CE    . LYS B 2 224  ? 129.351 133.170 136.668 1.00 17.80  ? 239  LYS B CE    1 
ATOM   8620  N  NZ    . LYS B 2 224  ? 128.517 132.454 137.672 1.00 17.80  ? 239  LYS B NZ    1 
ATOM   8621  N  N     . PHE B 2 225  ? 134.272 135.778 137.086 1.00 17.64  ? 240  PHE B N     1 
ATOM   8622  C  CA    . PHE B 2 225  ? 134.830 136.812 137.944 1.00 17.64  ? 240  PHE B CA    1 
ATOM   8623  C  C     . PHE B 2 225  ? 136.211 137.266 137.504 1.00 17.64  ? 240  PHE B C     1 
ATOM   8624  O  O     . PHE B 2 225  ? 136.793 138.143 138.150 1.00 17.64  ? 240  PHE B O     1 
ATOM   8625  C  CB    . PHE B 2 225  ? 134.915 136.317 139.387 1.00 17.64  ? 240  PHE B CB    1 
ATOM   8626  C  CG    . PHE B 2 225  ? 133.744 135.496 139.819 1.00 17.64  ? 240  PHE B CG    1 
ATOM   8627  C  CD1   . PHE B 2 225  ? 132.567 136.099 140.208 1.00 17.64  ? 240  PHE B CD1   1 
ATOM   8628  C  CD2   . PHE B 2 225  ? 133.829 134.120 139.852 1.00 17.64  ? 240  PHE B CD2   1 
ATOM   8629  C  CE1   . PHE B 2 225  ? 131.492 135.345 140.612 1.00 17.64  ? 240  PHE B CE1   1 
ATOM   8630  C  CE2   . PHE B 2 225  ? 132.759 133.361 140.255 1.00 17.64  ? 240  PHE B CE2   1 
ATOM   8631  C  CZ    . PHE B 2 225  ? 131.588 133.974 140.636 1.00 17.64  ? 240  PHE B CZ    1 
ATOM   8632  N  N     . ALA B 2 226  ? 136.752 136.692 136.437 1.00 16.09  ? 241  ALA B N     1 
ATOM   8633  C  CA    . ALA B 2 226  ? 138.136 136.925 136.056 1.00 16.09  ? 241  ALA B CA    1 
ATOM   8634  C  C     . ALA B 2 226  ? 138.242 138.149 135.159 1.00 16.09  ? 241  ALA B C     1 
ATOM   8635  O  O     . ALA B 2 226  ? 137.478 138.296 134.202 1.00 16.09  ? 241  ALA B O     1 
ATOM   8636  C  CB    . ALA B 2 226  ? 138.710 135.700 135.347 1.00 16.09  ? 241  ALA B CB    1 
ATOM   8637  N  N     . MET B 2 227  ? 139.190 139.029 135.480 1.00 38.40  ? 242  MET B N     1 
ATOM   8638  C  CA    . MET B 2 227  ? 139.471 140.161 134.605 1.00 38.40  ? 242  MET B CA    1 
ATOM   8639  C  C     . MET B 2 227  ? 140.000 139.693 133.256 1.00 38.40  ? 242  MET B C     1 
ATOM   8640  O  O     . MET B 2 227  ? 139.621 140.234 132.210 1.00 38.40  ? 242  MET B O     1 
ATOM   8641  C  CB    . MET B 2 227  ? 140.468 141.105 135.274 1.00 38.40  ? 242  MET B CB    1 
ATOM   8642  C  CG    . MET B 2 227  ? 139.888 141.903 136.425 1.00 38.40  ? 242  MET B CG    1 
ATOM   8643  S  SD    . MET B 2 227  ? 139.012 143.370 135.858 1.00 38.40  ? 242  MET B SD    1 
ATOM   8644  C  CE    . MET B 2 227  ? 140.360 144.275 135.105 1.00 38.40  ? 242  MET B CE    1 
ATOM   8645  N  N     . SER B 2 228  ? 140.878 138.689 133.260 1.00 22.65  ? 243  SER B N     1 
ATOM   8646  C  CA    . SER B 2 228  ? 141.455 138.117 132.044 1.00 22.65  ? 243  SER B CA    1 
ATOM   8647  C  C     . SER B 2 228  ? 141.051 136.651 131.986 1.00 22.65  ? 243  SER B C     1 
ATOM   8648  O  O     . SER B 2 228  ? 141.749 135.782 132.530 1.00 22.65  ? 243  SER B O     1 
ATOM   8649  C  CB    . SER B 2 228  ? 142.973 138.274 132.027 1.00 22.65  ? 243  SER B CB    1 
ATOM   8650  O  OG    . SER B 2 228  ? 143.350 139.602 132.338 1.00 22.65  ? 243  SER B OG    1 
ATOM   8651  N  N     . PRO B 2 229  ? 139.929 136.331 131.343 1.00 15.70  ? 244  PRO B N     1 
ATOM   8652  C  CA    . PRO B 2 229  ? 139.460 134.937 131.329 1.00 15.70  ? 244  PRO B CA    1 
ATOM   8653  C  C     . PRO B 2 229  ? 140.382 133.983 130.594 1.00 15.70  ? 244  PRO B C     1 
ATOM   8654  O  O     . PRO B 2 229  ? 140.256 132.766 130.773 1.00 15.70  ? 244  PRO B O     1 
ATOM   8655  C  CB    . PRO B 2 229  ? 138.094 135.037 130.635 1.00 15.70  ? 244  PRO B CB    1 
ATOM   8656  C  CG    . PRO B 2 229  ? 137.686 136.468 130.792 1.00 15.70  ? 244  PRO B CG    1 
ATOM   8657  C  CD    . PRO B 2 229  ? 138.961 137.245 130.721 1.00 15.70  ? 244  PRO B CD    1 
ATOM   8658  N  N     . SER B 2 230  ? 141.296 134.484 129.763 1.00 21.29  ? 245  SER B N     1 
ATOM   8659  C  CA    . SER B 2 230  ? 142.162 133.596 128.999 1.00 21.29  ? 245  SER B CA    1 
ATOM   8660  C  C     . SER B 2 230  ? 143.172 132.867 129.875 1.00 21.29  ? 245  SER B C     1 
ATOM   8661  O  O     . SER B 2 230  ? 143.644 131.794 129.485 1.00 21.29  ? 245  SER B O     1 
ATOM   8662  C  CB    . SER B 2 230  ? 142.894 134.381 127.912 1.00 21.29  ? 245  SER B CB    1 
ATOM   8663  O  OG    . SER B 2 230  ? 143.711 135.388 128.475 1.00 21.29  ? 245  SER B OG    1 
ATOM   8664  N  N     . ASN B 2 231  ? 143.515 133.418 131.041 1.00 12.53  ? 246  ASN B N     1 
ATOM   8665  C  CA    . ASN B 2 231  ? 144.505 132.772 131.894 1.00 12.53  ? 246  ASN B CA    1 
ATOM   8666  C  C     . ASN B 2 231  ? 143.999 131.448 132.447 1.00 12.53  ? 246  ASN B C     1 
ATOM   8667  O  O     . ASN B 2 231  ? 144.789 130.517 132.636 1.00 12.53  ? 246  ASN B O     1 
ATOM   8668  C  CB    . ASN B 2 231  ? 144.908 133.703 133.035 1.00 12.53  ? 246  ASN B CB    1 
ATOM   8669  C  CG    . ASN B 2 231  ? 145.769 134.855 132.565 1.00 12.53  ? 246  ASN B CG    1 
ATOM   8670  O  OD1   . ASN B 2 231  ? 146.412 134.779 131.521 1.00 12.53  ? 246  ASN B OD1   1 
ATOM   8671  N  ND2   . ASN B 2 231  ? 145.791 135.930 133.341 1.00 12.53  ? 246  ASN B ND2   1 
ATOM   8672  N  N     . PHE B 2 232  ? 142.699 131.335 132.700 1.00 11.43  ? 247  PHE B N     1 
ATOM   8673  C  CA    . PHE B 2 232  ? 142.122 130.099 133.223 1.00 11.43  ? 247  PHE B CA    1 
ATOM   8674  C  C     . PHE B 2 232  ? 142.073 129.088 132.088 1.00 11.43  ? 247  PHE B C     1 
ATOM   8675  O  O     . PHE B 2 232  ? 141.077 128.958 131.377 1.00 11.43  ? 247  PHE B O     1 
ATOM   8676  C  CB    . PHE B 2 232  ? 140.746 130.357 133.821 1.00 11.43  ? 247  PHE B CB    1 
ATOM   8677  C  CG    . PHE B 2 232  ? 140.789 131.112 135.113 1.00 11.43  ? 247  PHE B CG    1 
ATOM   8678  C  CD1   . PHE B 2 232  ? 141.035 132.472 135.127 1.00 11.43  ? 247  PHE B CD1   1 
ATOM   8679  C  CD2   . PHE B 2 232  ? 140.594 130.462 136.315 1.00 11.43  ? 247  PHE B CD2   1 
ATOM   8680  C  CE1   . PHE B 2 232  ? 141.083 133.164 136.310 1.00 11.43  ? 247  PHE B CE1   1 
ATOM   8681  C  CE2   . PHE B 2 232  ? 140.639 131.153 137.501 1.00 11.43  ? 247  PHE B CE2   1 
ATOM   8682  C  CZ    . PHE B 2 232  ? 140.884 132.504 137.499 1.00 11.43  ? 247  PHE B CZ    1 
ATOM   8683  N  N     . SER B 2 233  ? 143.175 128.368 131.917 1.00 15.80  ? 248  SER B N     1 
ATOM   8684  C  CA    . SER B 2 233  ? 143.339 127.427 130.818 1.00 15.80  ? 248  SER B CA    1 
ATOM   8685  C  C     . SER B 2 233  ? 142.685 126.092 131.169 1.00 15.80  ? 248  SER B C     1 
ATOM   8686  O  O     . SER B 2 233  ? 141.949 125.965 132.150 1.00 15.80  ? 248  SER B O     1 
ATOM   8687  C  CB    . SER B 2 233  ? 144.820 127.263 130.491 1.00 15.80  ? 248  SER B CB    1 
ATOM   8688  O  OG    . SER B 2 233  ? 145.462 128.523 130.398 1.00 15.80  ? 248  SER B OG    1 
ATOM   8689  N  N     . SER B 2 234  ? 142.950 125.077 130.354 1.00 14.33  ? 249  SER B N     1 
ATOM   8690  C  CA    . SER B 2 234  ? 142.499 123.718 130.622 1.00 14.33  ? 249  SER B CA    1 
ATOM   8691  C  C     . SER B 2 234  ? 143.445 122.762 129.911 1.00 14.33  ? 249  SER B C     1 
ATOM   8692  O  O     . SER B 2 234  ? 144.221 123.160 129.041 1.00 14.33  ? 249  SER B O     1 
ATOM   8693  C  CB    . SER B 2 234  ? 141.051 123.504 130.173 1.00 14.33  ? 249  SER B CB    1 
ATOM   8694  O  OG    . SER B 2 234  ? 140.639 122.168 130.399 1.00 14.33  ? 249  SER B OG    1 
ATOM   8695  N  N     . ALA B 2 235  ? 143.376 121.492 130.297 1.00 18.93  ? 250  ALA B N     1 
ATOM   8696  C  CA    . ALA B 2 235  ? 144.240 120.470 129.724 1.00 18.93  ? 250  ALA B CA    1 
ATOM   8697  C  C     . ALA B 2 235  ? 143.575 119.112 129.911 1.00 18.93  ? 250  ALA B C     1 
ATOM   8698  O  O     . ALA B 2 235  ? 142.432 119.015 130.363 1.00 18.93  ? 250  ALA B O     1 
ATOM   8699  C  CB    . ALA B 2 235  ? 145.634 120.508 130.354 1.00 18.93  ? 250  ALA B CB    1 
ATOM   8700  N  N     . ASP B 2 236  ? 144.303 118.060 129.550 1.00 33.48  ? 251  ASP B N     1 
ATOM   8701  C  CA    . ASP B 2 236  ? 143.838 116.690 129.705 1.00 33.48  ? 251  ASP B CA    1 
ATOM   8702  C  C     . ASP B 2 236  ? 144.933 115.858 130.353 1.00 33.48  ? 251  ASP B C     1 
ATOM   8703  O  O     . ASP B 2 236  ? 146.120 116.067 130.090 1.00 33.48  ? 251  ASP B O     1 
ATOM   8704  C  CB    . ASP B 2 236  ? 143.443 116.075 128.361 1.00 33.48  ? 251  ASP B CB    1 
ATOM   8705  C  CG    . ASP B 2 236  ? 142.215 116.725 127.763 1.00 33.48  ? 251  ASP B CG    1 
ATOM   8706  O  OD1   . ASP B 2 236  ? 142.312 117.892 127.329 1.00 33.48  ? 251  ASP B OD1   1 
ATOM   8707  O  OD2   . ASP B 2 236  ? 141.152 116.069 127.727 1.00 33.48  ? 251  ASP B OD2   1 
ATOM   8708  N  N     . CYS B 2 237  ? 144.528 114.910 131.196 1.00 45.21  ? 252  CYS B N     1 
ATOM   8709  C  CA    . CYS B 2 237  ? 145.481 114.105 131.944 1.00 45.21  ? 252  CYS B CA    1 
ATOM   8710  C  C     . CYS B 2 237  ? 144.926 112.701 132.126 1.00 45.21  ? 252  CYS B C     1 
ATOM   8711  O  O     . CYS B 2 237  ? 143.727 112.458 131.969 1.00 45.21  ? 252  CYS B O     1 
ATOM   8712  C  CB    . CYS B 2 237  ? 145.797 114.731 133.309 1.00 45.21  ? 252  CYS B CB    1 
ATOM   8713  S  SG    . CYS B 2 237  ? 146.562 116.368 133.239 1.00 45.21  ? 252  CYS B SG    1 
ATOM   8714  N  N     . GLN B 2 238  ? 145.823 111.773 132.450 1.00 59.54  ? 253  GLN B N     1 
ATOM   8715  C  CA    . GLN B 2 238  ? 145.460 110.402 132.777 1.00 59.54  ? 253  GLN B CA    1 
ATOM   8716  C  C     . GLN B 2 238  ? 146.121 110.007 134.088 1.00 59.54  ? 253  GLN B C     1 
ATOM   8717  O  O     . GLN B 2 238  ? 147.263 110.390 134.358 1.00 59.54  ? 253  GLN B O     1 
ATOM   8718  C  CB    . GLN B 2 238  ? 145.873 109.426 131.670 1.00 59.54  ? 253  GLN B CB    1 
ATOM   8719  C  CG    . GLN B 2 238  ? 145.154 109.637 130.349 1.00 59.54  ? 253  GLN B CG    1 
ATOM   8720  C  CD    . GLN B 2 238  ? 145.267 108.434 129.435 1.00 59.54  ? 253  GLN B CD    1 
ATOM   8721  O  OE1   . GLN B 2 238  ? 145.670 107.353 129.862 1.00 59.54  ? 253  GLN B OE1   1 
ATOM   8722  N  NE2   . GLN B 2 238  ? 144.910 108.616 128.169 1.00 59.54  ? 253  GLN B NE2   1 
ATOM   8723  N  N     . ASP B 2 239  ? 145.401 109.239 134.899 1.00 63.48  ? 254  ASP B N     1 
ATOM   8724  C  CA    . ASP B 2 239  ? 145.893 108.820 136.201 1.00 63.48  ? 254  ASP B CA    1 
ATOM   8725  C  C     . ASP B 2 239  ? 146.626 107.484 136.074 1.00 63.48  ? 254  ASP B C     1 
ATOM   8726  O  O     . ASP B 2 239  ? 146.955 107.031 134.974 1.00 63.48  ? 254  ASP B O     1 
ATOM   8727  C  CB    . ASP B 2 239  ? 144.744 108.753 137.205 1.00 63.48  ? 254  ASP B CB    1 
ATOM   8728  C  CG    . ASP B 2 239  ? 143.619 107.848 136.746 1.00 63.48  ? 254  ASP B CG    1 
ATOM   8729  O  OD1   . ASP B 2 239  ? 143.754 107.220 135.676 1.00 63.48  ? 254  ASP B OD1   1 
ATOM   8730  O  OD2   . ASP B 2 239  ? 142.597 107.768 137.458 1.00 63.48  ? 254  ASP B OD2   1 
ATOM   8731  N  N     . GLU B 2 240  ? 146.896 106.845 137.215 1.00 70.14  ? 255  GLU B N     1 
ATOM   8732  C  CA    . GLU B 2 240  ? 147.647 105.593 137.212 1.00 70.14  ? 255  GLU B CA    1 
ATOM   8733  C  C     . GLU B 2 240  ? 146.905 104.496 136.459 1.00 70.14  ? 255  GLU B C     1 
ATOM   8734  O  O     . GLU B 2 240  ? 147.498 103.787 135.638 1.00 70.14  ? 255  GLU B O     1 
ATOM   8735  C  CB    . GLU B 2 240  ? 147.935 105.148 138.646 1.00 70.14  ? 255  GLU B CB    1 
ATOM   8736  C  CG    . GLU B 2 240  ? 148.594 106.204 139.520 1.00 70.14  ? 255  GLU B CG    1 
ATOM   8737  C  CD    . GLU B 2 240  ? 147.596 107.179 140.118 1.00 70.14  ? 255  GLU B CD    1 
ATOM   8738  O  OE1   . GLU B 2 240  ? 146.378 106.969 139.939 1.00 70.14  ? 255  GLU B OE1   1 
ATOM   8739  O  OE2   . GLU B 2 240  ? 148.031 108.155 140.763 1.00 70.14  ? 255  GLU B OE2   1 
ATOM   8740  N  N     . LEU B 2 241  ? 145.609 104.344 136.718 1.00 63.43  ? 256  LEU B N     1 
ATOM   8741  C  CA    . LEU B 2 241  ? 144.820 103.287 136.100 1.00 63.43  ? 256  LEU B CA    1 
ATOM   8742  C  C     . LEU B 2 241  ? 144.400 103.614 134.673 1.00 63.43  ? 256  LEU B C     1 
ATOM   8743  O  O     . LEU B 2 241  ? 143.581 102.886 134.103 1.00 63.43  ? 256  LEU B O     1 
ATOM   8744  C  CB    . LEU B 2 241  ? 143.579 102.990 136.947 1.00 63.43  ? 256  LEU B CB    1 
ATOM   8745  C  CG    . LEU B 2 241  ? 143.817 102.633 138.416 1.00 63.43  ? 256  LEU B CG    1 
ATOM   8746  C  CD1   . LEU B 2 241  ? 142.527 102.164 139.068 1.00 63.43  ? 256  LEU B CD1   1 
ATOM   8747  C  CD2   . LEU B 2 241  ? 144.903 101.578 138.551 1.00 63.43  ? 256  LEU B CD2   1 
ATOM   8748  N  N     . GLY B 2 242  ? 144.936 104.681 134.086 1.00 59.00  ? 257  GLY B N     1 
ATOM   8749  C  CA    . GLY B 2 242  ? 144.590 105.050 132.731 1.00 59.00  ? 257  GLY B CA    1 
ATOM   8750  C  C     . GLY B 2 242  ? 143.273 105.773 132.574 1.00 59.00  ? 257  GLY B C     1 
ATOM   8751  O  O     . GLY B 2 242  ? 142.842 105.992 131.436 1.00 59.00  ? 257  GLY B O     1 
ATOM   8752  N  N     . ARG B 2 243  ? 142.616 106.144 133.670 1.00 51.88  ? 258  ARG B N     1 
ATOM   8753  C  CA    . ARG B 2 243  ? 141.355 106.862 133.572 1.00 51.88  ? 258  ARG B CA    1 
ATOM   8754  C  C     . ARG B 2 243  ? 141.575 108.253 132.989 1.00 51.88  ? 258  ARG B C     1 
ATOM   8755  O  O     . ARG B 2 243  ? 142.615 108.884 133.197 1.00 51.88  ? 258  ARG B O     1 
ATOM   8756  C  CB    . ARG B 2 243  ? 140.684 106.982 134.940 1.00 51.88  ? 258  ARG B CB    1 
ATOM   8757  C  CG    . ARG B 2 243  ? 140.727 105.729 135.791 1.00 51.88  ? 258  ARG B CG    1 
ATOM   8758  C  CD    . ARG B 2 243  ? 139.767 105.860 136.961 1.00 51.88  ? 258  ARG B CD    1 
ATOM   8759  N  NE    . ARG B 2 243  ? 140.220 105.151 138.151 1.00 51.88  ? 258  ARG B NE    1 
ATOM   8760  C  CZ    . ARG B 2 243  ? 140.907 105.711 139.136 1.00 51.88  ? 258  ARG B CZ    1 
ATOM   8761  N  NH1   . ARG B 2 243  ? 141.264 106.983 139.093 1.00 51.88  ? 258  ARG B NH1   1 
ATOM   8762  N  NH2   . ARG B 2 243  ? 141.242 104.977 140.193 1.00 51.88  ? 258  ARG B NH2   1 
ATOM   8763  N  N     . LYS B 2 244  ? 140.578 108.727 132.252 1.00 43.73  ? 259  LYS B N     1 
ATOM   8764  C  CA    . LYS B 2 244  ? 140.646 110.038 131.629 1.00 43.73  ? 259  LYS B CA    1 
ATOM   8765  C  C     . LYS B 2 244  ? 140.229 111.122 132.613 1.00 43.73  ? 259  LYS B C     1 
ATOM   8766  O  O     . LYS B 2 244  ? 139.474 110.878 133.559 1.00 43.73  ? 259  LYS B O     1 
ATOM   8767  C  CB    . LYS B 2 244  ? 139.749 110.082 130.394 1.00 43.73  ? 259  LYS B CB    1 
ATOM   8768  C  CG    . LYS B 2 244  ? 138.325 109.634 130.669 1.00 43.73  ? 259  LYS B CG    1 
ATOM   8769  C  CD    . LYS B 2 244  ? 137.493 109.611 129.404 1.00 43.73  ? 259  LYS B CD    1 
ATOM   8770  C  CE    . LYS B 2 244  ? 136.104 109.068 129.680 1.00 43.73  ? 259  LYS B CE    1 
ATOM   8771  N  NZ    . LYS B 2 244  ? 135.290 108.997 128.439 1.00 43.73  ? 259  LYS B NZ    1 
ATOM   8772  N  N     . GLY B 2 245  ? 140.736 112.329 132.386 1.00 32.59  ? 260  GLY B N     1 
ATOM   8773  C  CA    . GLY B 2 245  ? 140.379 113.454 133.224 1.00 32.59  ? 260  GLY B CA    1 
ATOM   8774  C  C     . GLY B 2 245  ? 141.028 114.749 132.789 1.00 32.59  ? 260  GLY B C     1 
ATOM   8775  O  O     . GLY B 2 245  ? 142.142 114.746 132.260 1.00 32.59  ? 260  GLY B O     1 
ATOM   8776  N  N     . SER B 2 246  ? 140.343 115.862 133.014 1.00 22.14  ? 261  SER B N     1 
ATOM   8777  C  CA    . SER B 2 246  ? 140.846 117.180 132.664 1.00 22.14  ? 261  SER B CA    1 
ATOM   8778  C  C     . SER B 2 246  ? 141.404 117.864 133.902 1.00 22.14  ? 261  SER B C     1 
ATOM   8779  O  O     . SER B 2 246  ? 141.296 117.366 135.024 1.00 22.14  ? 261  SER B O     1 
ATOM   8780  C  CB    . SER B 2 246  ? 139.746 118.035 132.026 1.00 22.14  ? 261  SER B CB    1 
ATOM   8781  O  OG    . SER B 2 246  ? 138.636 118.167 132.895 1.00 22.14  ? 261  SER B OG    1 
ATOM   8782  N  N     . LYS B 2 247  ? 142.007 119.026 133.685 1.00 17.66  ? 262  LYS B N     1 
ATOM   8783  C  CA    . LYS B 2 247  ? 142.685 119.733 134.765 1.00 17.66  ? 262  LYS B CA    1 
ATOM   8784  C  C     . LYS B 2 247  ? 142.723 121.212 134.419 1.00 17.66  ? 262  LYS B C     1 
ATOM   8785  O  O     . LYS B 2 247  ? 143.441 121.614 133.500 1.00 17.66  ? 262  LYS B O     1 
ATOM   8786  C  CB    . LYS B 2 247  ? 144.091 119.184 134.973 1.00 17.66  ? 262  LYS B CB    1 
ATOM   8787  C  CG    . LYS B 2 247  ? 144.950 120.027 135.887 1.00 17.66  ? 262  LYS B CG    1 
ATOM   8788  C  CD    . LYS B 2 247  ? 146.323 119.415 136.061 1.00 17.66  ? 262  LYS B CD    1 
ATOM   8789  C  CE    . LYS B 2 247  ? 146.249 118.076 136.770 1.00 17.66  ? 262  LYS B CE    1 
ATOM   8790  N  NZ    . LYS B 2 247  ? 147.609 117.530 137.021 1.00 17.66  ? 262  LYS B NZ    1 
ATOM   8791  N  N     . LEU B 2 248  ? 141.955 122.013 135.150 1.00 12.10  ? 263  LEU B N     1 
ATOM   8792  C  CA    . LEU B 2 248  ? 141.997 123.450 134.962 1.00 12.10  ? 263  LEU B CA    1 
ATOM   8793  C  C     . LEU B 2 248  ? 143.331 124.007 135.439 1.00 12.10  ? 263  LEU B C     1 
ATOM   8794  O  O     . LEU B 2 248  ? 144.116 123.342 136.116 1.00 12.10  ? 263  LEU B O     1 
ATOM   8795  C  CB    . LEU B 2 248  ? 140.859 124.138 135.711 1.00 12.10  ? 263  LEU B CB    1 
ATOM   8796  C  CG    . LEU B 2 248  ? 139.500 124.229 135.022 1.00 12.10  ? 263  LEU B CG    1 
ATOM   8797  C  CD1   . LEU B 2 248  ? 138.782 122.899 135.073 1.00 12.10  ? 263  LEU B CD1   1 
ATOM   8798  C  CD2   . LEU B 2 248  ? 138.662 125.321 135.661 1.00 12.10  ? 263  LEU B CD2   1 
ATOM   8799  N  N     . TYR B 2 249  ? 143.579 125.257 135.077 1.00 11.57  ? 264  TYR B N     1 
ATOM   8800  C  CA    . TYR B 2 249  ? 144.824 125.912 135.426 1.00 11.57  ? 264  TYR B CA    1 
ATOM   8801  C  C     . TYR B 2 249  ? 144.556 127.388 135.643 1.00 11.57  ? 264  TYR B C     1 
ATOM   8802  O  O     . TYR B 2 249  ? 143.505 127.912 135.273 1.00 11.57  ? 264  TYR B O     1 
ATOM   8803  C  CB    . TYR B 2 249  ? 145.882 125.744 134.330 1.00 11.57  ? 264  TYR B CB    1 
ATOM   8804  C  CG    . TYR B 2 249  ? 146.565 124.397 134.285 1.00 11.57  ? 264  TYR B CG    1 
ATOM   8805  C  CD1   . TYR B 2 249  ? 146.024 123.346 133.565 1.00 11.57  ? 264  TYR B CD1   1 
ATOM   8806  C  CD2   . TYR B 2 249  ? 147.765 124.187 134.944 1.00 11.57  ? 264  TYR B CD2   1 
ATOM   8807  C  CE1   . TYR B 2 249  ? 146.651 122.117 133.517 1.00 11.57  ? 264  TYR B CE1   1 
ATOM   8808  C  CE2   . TYR B 2 249  ? 148.400 122.964 134.900 1.00 11.57  ? 264  TYR B CE2   1 
ATOM   8809  C  CZ    . TYR B 2 249  ? 147.840 121.933 134.186 1.00 11.57  ? 264  TYR B CZ    1 
ATOM   8810  O  OH    . TYR B 2 249  ? 148.476 120.713 134.142 1.00 11.57  ? 264  TYR B OH    1 
ATOM   8811  N  N     . TYR B 2 250  ? 145.526 128.053 136.253 1.00 14.96  ? 265  TYR B N     1 
ATOM   8812  C  CA    . TYR B 2 250  ? 145.642 129.499 136.178 1.00 14.96  ? 265  TYR B CA    1 
ATOM   8813  C  C     . TYR B 2 250  ? 147.096 129.826 135.902 1.00 14.96  ? 265  TYR B C     1 
ATOM   8814  O  O     . TYR B 2 250  ? 147.991 129.261 136.534 1.00 14.96  ? 265  TYR B O     1 
ATOM   8815  C  CB    . TYR B 2 250  ? 145.169 130.196 137.455 1.00 14.96  ? 265  TYR B CB    1 
ATOM   8816  C  CG    . TYR B 2 250  ? 145.489 131.674 137.441 1.00 14.96  ? 265  TYR B CG    1 
ATOM   8817  C  CD1   . TYR B 2 250  ? 144.740 132.558 136.685 1.00 14.96  ? 265  TYR B CD1   1 
ATOM   8818  C  CD2   . TYR B 2 250  ? 146.558 132.178 138.160 1.00 14.96  ? 265  TYR B CD2   1 
ATOM   8819  C  CE1   . TYR B 2 250  ? 145.041 133.901 136.658 1.00 14.96  ? 265  TYR B CE1   1 
ATOM   8820  C  CE2   . TYR B 2 250  ? 146.862 133.518 138.137 1.00 14.96  ? 265  TYR B CE2   1 
ATOM   8821  C  CZ    . TYR B 2 250  ? 146.104 134.373 137.386 1.00 14.96  ? 265  TYR B CZ    1 
ATOM   8822  O  OH    . TYR B 2 250  ? 146.414 135.710 137.368 1.00 14.96  ? 265  TYR B OH    1 
ATOM   8823  N  N     . SER B 2 251  ? 147.331 130.734 134.959 1.00 14.42  ? 266  SER B N     1 
ATOM   8824  C  CA    . SER B 2 251  ? 148.689 131.085 134.557 1.00 14.42  ? 266  SER B CA    1 
ATOM   8825  C  C     . SER B 2 251  ? 149.262 132.081 135.559 1.00 14.42  ? 266  SER B C     1 
ATOM   8826  O  O     . SER B 2 251  ? 149.317 133.290 135.324 1.00 14.42  ? 266  SER B O     1 
ATOM   8827  C  CB    . SER B 2 251  ? 148.702 131.649 133.143 1.00 14.42  ? 266  SER B CB    1 
ATOM   8828  O  OG    . SER B 2 251  ? 148.227 130.695 132.212 1.00 14.42  ? 266  SER B OG    1 
ATOM   8829  N  N     . PHE B 2 252  ? 149.699 131.552 136.703 1.00 12.09  ? 267  PHE B N     1 
ATOM   8830  C  CA    . PHE B 2 252  ? 150.402 132.371 137.674 1.00 12.09  ? 267  PHE B CA    1 
ATOM   8831  C  C     . PHE B 2 252  ? 151.686 132.903 137.045 1.00 12.09  ? 267  PHE B C     1 
ATOM   8832  O  O     . PHE B 2 252  ? 152.207 132.313 136.094 1.00 12.09  ? 267  PHE B O     1 
ATOM   8833  C  CB    . PHE B 2 252  ? 150.734 131.564 138.928 1.00 12.09  ? 267  PHE B CB    1 
ATOM   8834  C  CG    . PHE B 2 252  ? 149.544 131.222 139.776 1.00 12.09  ? 267  PHE B CG    1 
ATOM   8835  C  CD1   . PHE B 2 252  ? 149.131 132.070 140.784 1.00 12.09  ? 267  PHE B CD1   1 
ATOM   8836  C  CD2   . PHE B 2 252  ? 148.856 130.042 139.582 1.00 12.09  ? 267  PHE B CD2   1 
ATOM   8837  C  CE1   . PHE B 2 252  ? 148.047 131.753 141.571 1.00 12.09  ? 267  PHE B CE1   1 
ATOM   8838  C  CE2   . PHE B 2 252  ? 147.771 129.720 140.368 1.00 12.09  ? 267  PHE B CE2   1 
ATOM   8839  C  CZ    . PHE B 2 252  ? 147.366 130.577 141.362 1.00 12.09  ? 267  PHE B CZ    1 
ATOM   8840  N  N     . PRO B 2 253  ? 152.211 134.022 137.552 1.00 18.38  ? 268  PRO B N     1 
ATOM   8841  C  CA    . PRO B 2 253  ? 153.420 134.598 136.937 1.00 18.38  ? 268  PRO B CA    1 
ATOM   8842  C  C     . PRO B 2 253  ? 154.587 133.630 136.854 1.00 18.38  ? 268  PRO B C     1 
ATOM   8843  O  O     . PRO B 2 253  ? 155.348 133.668 135.880 1.00 18.38  ? 268  PRO B O     1 
ATOM   8844  C  CB    . PRO B 2 253  ? 153.735 135.788 137.855 1.00 18.38  ? 268  PRO B CB    1 
ATOM   8845  C  CG    . PRO B 2 253  ? 152.425 136.167 138.422 1.00 18.38  ? 268  PRO B CG    1 
ATOM   8846  C  CD    . PRO B 2 253  ? 151.677 134.881 138.620 1.00 18.38  ? 268  PRO B CD    1 
ATOM   8847  N  N     . TRP B 2 254  ? 154.755 132.762 137.852 1.00 19.98  ? 269  TRP B N     1 
ATOM   8848  C  CA    . TRP B 2 254  ? 155.818 131.765 137.785 1.00 19.98  ? 269  TRP B CA    1 
ATOM   8849  C  C     . TRP B 2 254  ? 155.459 130.617 136.850 1.00 19.98  ? 269  TRP B C     1 
ATOM   8850  O  O     . TRP B 2 254  ? 156.331 130.088 136.154 1.00 19.98  ? 269  TRP B O     1 
ATOM   8851  C  CB    . TRP B 2 254  ? 156.138 131.235 139.182 1.00 19.98  ? 269  TRP B CB    1 
ATOM   8852  C  CG    . TRP B 2 254  ? 154.966 130.657 139.902 1.00 19.98  ? 269  TRP B CG    1 
ATOM   8853  C  CD1   . TRP B 2 254  ? 154.484 129.386 139.802 1.00 19.98  ? 269  TRP B CD1   1 
ATOM   8854  C  CD2   . TRP B 2 254  ? 154.134 131.327 140.852 1.00 19.98  ? 269  TRP B CD2   1 
ATOM   8855  N  NE1   . TRP B 2 254  ? 153.397 129.225 140.626 1.00 19.98  ? 269  TRP B NE1   1 
ATOM   8856  C  CE2   . TRP B 2 254  ? 153.163 130.404 141.282 1.00 19.98  ? 269  TRP B CE2   1 
ATOM   8857  C  CE3   . TRP B 2 254  ? 154.114 132.621 141.378 1.00 19.98  ? 269  TRP B CE3   1 
ATOM   8858  C  CZ2   . TRP B 2 254  ? 152.184 130.733 142.212 1.00 19.98  ? 269  TRP B CZ2   1 
ATOM   8859  C  CZ3   . TRP B 2 254  ? 153.143 132.945 142.300 1.00 19.98  ? 269  TRP B CZ3   1 
ATOM   8860  C  CH2   . TRP B 2 254  ? 152.191 132.006 142.708 1.00 19.98  ? 269  TRP B CH2   1 
ATOM   8861  N  N     . GLY B 2 255  ? 154.194 130.219 136.817 1.00 14.47  ? 270  GLY B N     1 
ATOM   8862  C  CA    . GLY B 2 255  ? 153.786 129.123 135.960 1.00 14.47  ? 270  GLY B CA    1 
ATOM   8863  C  C     . GLY B 2 255  ? 152.395 128.651 136.310 1.00 14.47  ? 270  GLY B C     1 
ATOM   8864  O  O     . GLY B 2 255  ? 151.812 129.036 137.327 1.00 14.47  ? 270  GLY B O     1 
ATOM   8865  N  N     . LYS B 2 256  ? 151.871 127.795 135.441 1.00 13.97  ? 271  LYS B N     1 
ATOM   8866  C  CA    . LYS B 2 256  ? 150.498 127.333 135.577 1.00 13.97  ? 271  LYS B CA    1 
ATOM   8867  C  C     . LYS B 2 256  ? 150.373 126.322 136.709 1.00 13.97  ? 271  LYS B C     1 
ATOM   8868  O  O     . LYS B 2 256  ? 151.206 125.424 136.858 1.00 13.97  ? 271  LYS B O     1 
ATOM   8869  C  CB    . LYS B 2 256  ? 150.026 126.719 134.264 1.00 13.97  ? 271  LYS B CB    1 
ATOM   8870  C  CG    . LYS B 2 256  ? 150.337 127.581 133.058 1.00 13.97  ? 271  LYS B CG    1 
ATOM   8871  C  CD    . LYS B 2 256  ? 149.868 126.932 131.775 1.00 13.97  ? 271  LYS B CD    1 
ATOM   8872  C  CE    . LYS B 2 256  ? 150.255 127.777 130.578 1.00 13.97  ? 271  LYS B CE    1 
ATOM   8873  N  NZ    . LYS B 2 256  ? 149.855 127.140 129.297 1.00 13.97  ? 271  LYS B NZ    1 
ATOM   8874  N  N     . GLU B 2 257  ? 149.318 126.471 137.511 1.00 16.72  ? 272  GLU B N     1 
ATOM   8875  C  CA    . GLU B 2 257  ? 149.053 125.591 138.637 1.00 16.72  ? 272  GLU B CA    1 
ATOM   8876  C  C     . GLU B 2 257  ? 147.629 125.059 138.552 1.00 16.72  ? 272  GLU B C     1 
ATOM   8877  O  O     . GLU B 2 257  ? 146.717 125.783 138.139 1.00 16.72  ? 272  GLU B O     1 
ATOM   8878  C  CB    . GLU B 2 257  ? 149.245 126.323 139.972 1.00 16.72  ? 272  GLU B CB    1 
ATOM   8879  C  CG    . GLU B 2 257  ? 150.548 127.101 140.088 1.00 16.72  ? 272  GLU B CG    1 
ATOM   8880  C  CD    . GLU B 2 257  ? 151.716 126.255 140.557 1.00 16.72  ? 272  GLU B CD    1 
ATOM   8881  O  OE1   . GLU B 2 257  ? 151.498 125.081 140.926 1.00 16.72  ? 272  GLU B OE1   1 
ATOM   8882  O  OE2   . GLU B 2 257  ? 152.853 126.772 140.562 1.00 16.72  ? 272  GLU B OE2   1 
ATOM   8883  N  N     . PRO B 2 258  ? 147.406 123.813 138.945 1.00 11.77  ? 273  PRO B N     1 
ATOM   8884  C  CA    . PRO B 2 258  ? 146.068 123.223 138.810 1.00 11.77  ? 273  PRO B CA    1 
ATOM   8885  C  C     . PRO B 2 258  ? 145.092 123.658 139.892 1.00 11.77  ? 273  PRO B C     1 
ATOM   8886  O  O     . PRO B 2 258  ? 144.927 122.961 140.898 1.00 11.77  ? 273  PRO B O     1 
ATOM   8887  C  CB    . PRO B 2 258  ? 146.347 121.718 138.890 1.00 11.77  ? 273  PRO B CB    1 
ATOM   8888  C  CG    . PRO B 2 258  ? 147.571 121.619 139.716 1.00 11.77  ? 273  PRO B CG    1 
ATOM   8889  C  CD    . PRO B 2 258  ? 148.405 122.824 139.381 1.00 11.77  ? 273  PRO B CD    1 
ATOM   8890  N  N     . ILE B 2 259  ? 144.434 124.805 139.700 1.00 13.80  ? 274  ILE B N     1 
ATOM   8891  C  CA    . ILE B 2 259  ? 143.452 125.263 140.676 1.00 13.80  ? 274  ILE B CA    1 
ATOM   8892  C  C     . ILE B 2 259  ? 142.254 124.331 140.763 1.00 13.80  ? 274  ILE B C     1 
ATOM   8893  O  O     . ILE B 2 259  ? 141.497 124.395 141.736 1.00 13.80  ? 274  ILE B O     1 
ATOM   8894  C  CB    . ILE B 2 259  ? 142.965 126.687 140.356 1.00 13.80  ? 274  ILE B CB    1 
ATOM   8895  C  CG1   . ILE B 2 259  ? 141.940 126.645 139.228 1.00 13.80  ? 274  ILE B CG1   1 
ATOM   8896  C  CG2   . ILE B 2 259  ? 144.126 127.590 139.984 1.00 13.80  ? 274  ILE B CG2   1 
ATOM   8897  C  CD1   . ILE B 2 259  ? 141.421 127.993 138.833 1.00 13.80  ? 274  ILE B CD1   1 
ATOM   8898  N  N     . GLU B 2 260  ? 142.047 123.469 139.770 1.00 13.60  ? 275  GLU B N     1 
ATOM   8899  C  CA    . GLU B 2 260  ? 140.911 122.560 139.792 1.00 13.60  ? 275  GLU B CA    1 
ATOM   8900  C  C     . GLU B 2 260  ? 141.204 121.379 138.881 1.00 13.60  ? 275  GLU B C     1 
ATOM   8901  O  O     . GLU B 2 260  ? 141.785 121.549 137.808 1.00 13.60  ? 275  GLU B O     1 
ATOM   8902  C  CB    . GLU B 2 260  ? 139.623 123.270 139.356 1.00 13.60  ? 275  GLU B CB    1 
ATOM   8903  C  CG    . GLU B 2 260  ? 138.372 122.414 139.482 1.00 13.60  ? 275  GLU B CG    1 
ATOM   8904  C  CD    . GLU B 2 260  ? 137.138 123.223 139.842 1.00 13.60  ? 275  GLU B CD    1 
ATOM   8905  O  OE1   . GLU B 2 260  ? 137.206 124.470 139.808 1.00 13.60  ? 275  GLU B OE1   1 
ATOM   8906  O  OE2   . GLU B 2 260  ? 136.100 122.610 140.167 1.00 13.60  ? 275  GLU B OE2   1 
ATOM   8907  N  N     . THR B 2 261  ? 140.800 120.187 139.317 1.00 20.04  ? 276  THR B N     1 
ATOM   8908  C  CA    . THR B 2 261  ? 141.005 118.960 138.562 1.00 20.04  ? 276  THR B CA    1 
ATOM   8909  C  C     . THR B 2 261  ? 139.716 118.154 138.527 1.00 20.04  ? 276  THR B C     1 
ATOM   8910  O  O     . THR B 2 261  ? 138.924 118.176 139.472 1.00 20.04  ? 276  THR B O     1 
ATOM   8911  C  CB    . THR B 2 261  ? 142.112 118.086 139.165 1.00 20.04  ? 276  THR B CB    1 
ATOM   8912  O  OG1   . THR B 2 261  ? 141.694 117.605 140.448 1.00 20.04  ? 276  THR B OG1   1 
ATOM   8913  C  CG2   . THR B 2 261  ? 143.403 118.870 139.319 1.00 20.04  ? 276  THR B CG2   1 
ATOM   8914  N  N     . LEU B 2 262  ? 139.522 117.427 137.431 1.00 24.68  ? 277  LEU B N     1 
ATOM   8915  C  CA    . LEU B 2 262  ? 138.387 116.528 137.269 1.00 24.68  ? 277  LEU B CA    1 
ATOM   8916  C  C     . LEU B 2 262  ? 138.907 115.173 136.821 1.00 24.68  ? 277  LEU B C     1 
ATOM   8917  O  O     . LEU B 2 262  ? 139.744 115.099 135.917 1.00 24.68  ? 277  LEU B O     1 
ATOM   8918  C  CB    . LEU B 2 262  ? 137.378 117.067 136.249 1.00 24.68  ? 277  LEU B CB    1 
ATOM   8919  C  CG    . LEU B 2 262  ? 136.819 118.480 136.437 1.00 24.68  ? 277  LEU B CG    1 
ATOM   8920  C  CD1   . LEU B 2 262  ? 137.732 119.525 135.817 1.00 24.68  ? 277  LEU B CD1   1 
ATOM   8921  C  CD2   . LEU B 2 262  ? 135.416 118.586 135.862 1.00 24.68  ? 277  LEU B CD2   1 
ATOM   8922  N  N     . TRP B 2 263  ? 138.417 114.107 137.448 1.00 32.98  ? 278  TRP B N     1 
ATOM   8923  C  CA    . TRP B 2 263  ? 138.846 112.750 137.132 1.00 32.98  ? 278  TRP B CA    1 
ATOM   8924  C  C     . TRP B 2 263  ? 137.622 111.878 136.923 1.00 32.98  ? 278  TRP B C     1 
ATOM   8925  O  O     . TRP B 2 263  ? 136.797 111.739 137.829 1.00 32.98  ? 278  TRP B O     1 
ATOM   8926  C  CB    . TRP B 2 263  ? 139.721 112.167 138.244 1.00 32.98  ? 278  TRP B CB    1 
ATOM   8927  C  CG    . TRP B 2 263  ? 140.987 112.911 138.440 1.00 32.98  ? 278  TRP B CG    1 
ATOM   8928  C  CD1   . TRP B 2 263  ? 141.285 113.759 139.460 1.00 32.98  ? 278  TRP B CD1   1 
ATOM   8929  C  CD2   . TRP B 2 263  ? 142.133 112.888 137.585 1.00 32.98  ? 278  TRP B CD2   1 
ATOM   8930  N  NE1   . TRP B 2 263  ? 142.550 114.266 139.298 1.00 32.98  ? 278  TRP B NE1   1 
ATOM   8931  C  CE2   . TRP B 2 263  ? 143.092 113.747 138.152 1.00 32.98  ? 278  TRP B CE2   1 
ATOM   8932  C  CE3   . TRP B 2 263  ? 142.442 112.224 136.395 1.00 32.98  ? 278  TRP B CE3   1 
ATOM   8933  C  CZ2   . TRP B 2 263  ? 144.339 113.959 137.571 1.00 32.98  ? 278  TRP B CZ2   1 
ATOM   8934  C  CZ3   . TRP B 2 263  ? 143.678 112.436 135.820 1.00 32.98  ? 278  TRP B CZ3   1 
ATOM   8935  C  CH2   . TRP B 2 263  ? 144.612 113.295 136.408 1.00 32.98  ? 278  TRP B CH2   1 
ATOM   8936  N  N     . ASN B 2 264  ? 137.517 111.271 135.744 1.00 34.54  ? 279  ASN B N     1 
ATOM   8937  C  CA    . ASN B 2 264  ? 136.396 110.382 135.449 1.00 34.54  ? 279  ASN B CA    1 
ATOM   8938  C  C     . ASN B 2 264  ? 136.657 109.027 136.107 1.00 34.54  ? 279  ASN B C     1 
ATOM   8939  O  O     . ASN B 2 264  ? 136.937 108.017 135.457 1.00 34.54  ? 279  ASN B O     1 
ATOM   8940  C  CB    . ASN B 2 264  ? 136.190 110.249 133.947 1.00 34.54  ? 279  ASN B CB    1 
ATOM   8941  C  CG    . ASN B 2 264  ? 134.873 109.585 133.601 1.00 34.54  ? 279  ASN B CG    1 
ATOM   8942  O  OD1   . ASN B 2 264  ? 133.913 110.251 133.221 1.00 34.54  ? 279  ASN B OD1   1 
ATOM   8943  N  ND2   . ASN B 2 264  ? 134.820 108.266 133.738 1.00 34.54  ? 279  ASN B ND2   1 
ATOM   8944  N  N     . LEU B 2 265  ? 136.574 109.029 137.435 1.00 36.91  ? 280  LEU B N     1 
ATOM   8945  C  CA    . LEU B 2 265  ? 136.739 107.803 138.200 1.00 36.91  ? 280  LEU B CA    1 
ATOM   8946  C  C     . LEU B 2 265  ? 135.687 106.788 137.779 1.00 36.91  ? 280  LEU B C     1 
ATOM   8947  O  O     . LEU B 2 265  ? 134.497 107.105 137.704 1.00 36.91  ? 280  LEU B O     1 
ATOM   8948  C  CB    . LEU B 2 265  ? 136.624 108.100 139.693 1.00 36.91  ? 280  LEU B CB    1 
ATOM   8949  C  CG    . LEU B 2 265  ? 137.407 109.312 140.203 1.00 36.91  ? 280  LEU B CG    1 
ATOM   8950  C  CD1   . LEU B 2 265  ? 137.075 109.596 141.655 1.00 36.91  ? 280  LEU B CD1   1 
ATOM   8951  C  CD2   . LEU B 2 265  ? 138.899 109.107 140.028 1.00 36.91  ? 280  LEU B CD2   1 
ATOM   8952  N  N     . GLY B 2 266  ? 136.125 105.568 137.502 1.00 46.92  ? 281  GLY B N     1 
ATOM   8953  C  CA    . GLY B 2 266  ? 135.241 104.531 137.008 1.00 46.92  ? 281  GLY B CA    1 
ATOM   8954  C  C     . GLY B 2 266  ? 134.402 103.912 138.103 1.00 46.92  ? 281  GLY B C     1 
ATOM   8955  O  O     . GLY B 2 266  ? 133.981 104.577 139.056 1.00 46.92  ? 281  GLY B O     1 
ATOM   8956  N  N     . ASP B 2 267  ? 134.154 102.609 137.965 1.00 63.87  ? 282  ASP B N     1 
ATOM   8957  C  CA    . ASP B 2 267  ? 133.382 101.872 138.957 1.00 63.87  ? 282  ASP B CA    1 
ATOM   8958  C  C     . ASP B 2 267  ? 134.203 101.512 140.188 1.00 63.87  ? 282  ASP B C     1 
ATOM   8959  O  O     . ASP B 2 267  ? 133.644 100.968 141.146 1.00 63.87  ? 282  ASP B O     1 
ATOM   8960  C  CB    . ASP B 2 267  ? 132.810 100.601 138.325 1.00 63.87  ? 282  ASP B CB    1 
ATOM   8961  C  CG    . ASP B 2 267  ? 131.603 100.072 139.069 1.00 63.87  ? 282  ASP B CG    1 
ATOM   8962  O  OD1   . ASP B 2 267  ? 131.095 100.783 139.960 1.00 63.87  ? 282  ASP B OD1   1 
ATOM   8963  O  OD2   . ASP B 2 267  ? 131.160 98.945  138.762 1.00 63.87  ? 282  ASP B OD2   1 
ATOM   8964  N  N     . GLN B 2 268  ? 135.506 101.803 140.184 1.00 65.53  ? 283  GLN B N     1 
ATOM   8965  C  CA    . GLN B 2 268  ? 136.376 101.376 141.276 1.00 65.53  ? 283  GLN B CA    1 
ATOM   8966  C  C     . GLN B 2 268  ? 136.030 102.073 142.587 1.00 65.53  ? 283  GLN B C     1 
ATOM   8967  O  O     . GLN B 2 268  ? 136.098 101.456 143.657 1.00 65.53  ? 283  GLN B O     1 
ATOM   8968  C  CB    . GLN B 2 268  ? 137.840 101.631 140.912 1.00 65.53  ? 283  GLN B CB    1 
ATOM   8969  C  CG    . GLN B 2 268  ? 138.334 100.861 139.695 1.00 65.53  ? 283  GLN B CG    1 
ATOM   8970  C  CD    . GLN B 2 268  ? 137.992 101.548 138.389 1.00 65.53  ? 283  GLN B CD    1 
ATOM   8971  O  OE1   . GLN B 2 268  ? 137.525 102.686 138.378 1.00 65.53  ? 283  GLN B OE1   1 
ATOM   8972  N  NE2   . GLN B 2 268  ? 138.224 100.859 137.277 1.00 65.53  ? 283  GLN B NE2   1 
ATOM   8973  N  N     . GLU B 2 269  ? 135.675 103.359 142.531 1.00 61.20  ? 284  GLU B N     1 
ATOM   8974  C  CA    . GLU B 2 269  ? 135.567 104.148 143.756 1.00 61.20  ? 284  GLU B CA    1 
ATOM   8975  C  C     . GLU B 2 269  ? 134.478 103.621 144.680 1.00 61.20  ? 284  GLU B C     1 
ATOM   8976  O  O     . GLU B 2 269  ? 134.686 103.516 145.894 1.00 61.20  ? 284  GLU B O     1 
ATOM   8977  C  CB    . GLU B 2 269  ? 135.320 105.613 143.411 1.00 61.20  ? 284  GLU B CB    1 
ATOM   8978  C  CG    . GLU B 2 269  ? 136.481 106.249 142.683 1.00 61.20  ? 284  GLU B CG    1 
ATOM   8979  C  CD    . GLU B 2 269  ? 137.772 106.184 143.475 1.00 61.20  ? 284  GLU B CD    1 
ATOM   8980  O  OE1   . GLU B 2 269  ? 137.719 106.314 144.716 1.00 61.20  ? 284  GLU B OE1   1 
ATOM   8981  O  OE2   . GLU B 2 269  ? 138.840 105.999 142.856 1.00 61.20  ? 284  GLU B OE2   1 
ATOM   8982  N  N     . LEU B 2 270  ? 133.313 103.278 144.132 1.00 66.36  ? 285  LEU B N     1 
ATOM   8983  C  CA    . LEU B 2 270  ? 132.259 102.720 144.969 1.00 66.36  ? 285  LEU B CA    1 
ATOM   8984  C  C     . LEU B 2 270  ? 132.576 101.311 145.451 1.00 66.36  ? 285  LEU B C     1 
ATOM   8985  O  O     . LEU B 2 270  ? 131.864 100.799 146.321 1.00 66.36  ? 285  LEU B O     1 
ATOM   8986  C  CB    . LEU B 2 270  ? 130.924 102.724 144.221 1.00 66.36  ? 285  LEU B CB    1 
ATOM   8987  C  CG    . LEU B 2 270  ? 130.208 104.072 144.132 1.00 66.36  ? 285  LEU B CG    1 
ATOM   8988  C  CD1   . LEU B 2 270  ? 128.857 103.920 143.452 1.00 66.36  ? 285  LEU B CD1   1 
ATOM   8989  C  CD2   . LEU B 2 270  ? 130.047 104.673 145.515 1.00 66.36  ? 285  LEU B CD2   1 
ATOM   8990  N  N     . LEU B 2 271  ? 133.611 100.671 144.904 1.00 69.87  ? 286  LEU B N     1 
ATOM   8991  C  CA    . LEU B 2 271  ? 133.986 99.339  145.365 1.00 69.87  ? 286  LEU B CA    1 
ATOM   8992  C  C     . LEU B 2 271  ? 134.770 99.388  146.672 1.00 69.87  ? 286  LEU B C     1 
ATOM   8993  O  O     . LEU B 2 271  ? 134.539 98.564  147.563 1.00 69.87  ? 286  LEU B O     1 
ATOM   8994  C  CB    . LEU B 2 271  ? 134.790 98.615  144.286 1.00 69.87  ? 286  LEU B CB    1 
ATOM   8995  C  CG    . LEU B 2 271  ? 134.041 98.358  142.978 1.00 69.87  ? 286  LEU B CG    1 
ATOM   8996  C  CD1   . LEU B 2 271  ? 134.901 97.558  142.013 1.00 69.87  ? 286  LEU B CD1   1 
ATOM   8997  C  CD2   . LEU B 2 271  ? 132.720 97.652  143.242 1.00 69.87  ? 286  LEU B CD2   1 
ATOM   8998  N  N     . HIS B 2 272  ? 135.695 100.337 146.815 1.00 74.81  ? 287  HIS B N     1 
ATOM   8999  C  CA    . HIS B 2 272  ? 136.527 100.395 148.011 1.00 74.81  ? 287  HIS B CA    1 
ATOM   9000  C  C     . HIS B 2 272  ? 135.954 101.300 149.096 1.00 74.81  ? 287  HIS B C     1 
ATOM   9001  O  O     . HIS B 2 272  ? 136.612 101.505 150.121 1.00 74.81  ? 287  HIS B O     1 
ATOM   9002  C  CB    . HIS B 2 272  ? 137.956 100.833 147.655 1.00 74.81  ? 287  HIS B CB    1 
ATOM   9003  C  CG    . HIS B 2 272  ? 138.069 102.251 147.188 1.00 74.81  ? 287  HIS B CG    1 
ATOM   9004  N  ND1   . HIS B 2 272  ? 137.944 103.329 148.038 1.00 74.81  ? 287  HIS B ND1   1 
ATOM   9005  C  CD2   . HIS B 2 272  ? 138.323 102.767 145.962 1.00 74.81  ? 287  HIS B CD2   1 
ATOM   9006  C  CE1   . HIS B 2 272  ? 138.101 104.448 147.354 1.00 74.81  ? 287  HIS B CE1   1 
ATOM   9007  N  NE2   . HIS B 2 272  ? 138.333 104.135 146.092 1.00 74.81  ? 287  HIS B NE2   1 
ATOM   9008  N  N     . THR B 2 273  ? 134.754 101.848 148.895 1.00 72.25  ? 288  THR B N     1 
ATOM   9009  C  CA    . THR B 2 273  ? 134.006 102.484 149.969 1.00 72.25  ? 288  THR B CA    1 
ATOM   9010  C  C     . THR B 2 273  ? 132.752 101.716 150.352 1.00 72.25  ? 288  THR B C     1 
ATOM   9011  O  O     . THR B 2 273  ? 132.235 101.919 151.454 1.00 72.25  ? 288  THR B O     1 
ATOM   9012  C  CB    . THR B 2 273  ? 133.611 103.918 149.587 1.00 72.25  ? 288  THR B CB    1 
ATOM   9013  O  OG1   . THR B 2 273  ? 132.986 103.918 148.297 1.00 72.25  ? 288  THR B OG1   1 
ATOM   9014  C  CG2   . THR B 2 273  ? 134.834 104.818 149.562 1.00 72.25  ? 288  THR B CG2   1 
ATOM   9015  N  N     . TYR B 2 274  ? 132.253 100.853 149.471 1.00 69.44  ? 289  TYR B N     1 
ATOM   9016  C  CA    . TYR B 2 274  ? 131.173 99.918  149.782 1.00 69.44  ? 289  TYR B CA    1 
ATOM   9017  C  C     . TYR B 2 274  ? 131.588 98.535  149.298 1.00 69.44  ? 289  TYR B C     1 
ATOM   9018  O  O     . TYR B 2 274  ? 131.033 98.009  148.326 1.00 69.44  ? 289  TYR B O     1 
ATOM   9019  C  CB    . TYR B 2 274  ? 129.856 100.351 149.137 1.00 69.44  ? 289  TYR B CB    1 
ATOM   9020  C  CG    . TYR B 2 274  ? 129.245 101.613 149.710 1.00 69.44  ? 289  TYR B CG    1 
ATOM   9021  C  CD1   . TYR B 2 274  ? 129.706 102.867 149.333 1.00 69.44  ? 289  TYR B CD1   1 
ATOM   9022  C  CD2   . TYR B 2 274  ? 128.189 101.549 150.611 1.00 69.44  ? 289  TYR B CD2   1 
ATOM   9023  C  CE1   . TYR B 2 274  ? 129.145 104.020 149.848 1.00 69.44  ? 289  TYR B CE1   1 
ATOM   9024  C  CE2   . TYR B 2 274  ? 127.621 102.698 151.130 1.00 69.44  ? 289  TYR B CE2   1 
ATOM   9025  C  CZ    . TYR B 2 274  ? 128.103 103.930 150.745 1.00 69.44  ? 289  TYR B CZ    1 
ATOM   9026  O  OH    . TYR B 2 274  ? 127.540 105.075 151.259 1.00 69.44  ? 289  TYR B OH    1 
ATOM   9027  N  N     . PRO B 2 275  ? 132.573 97.914  149.957 1.00 63.32  ? 290  PRO B N     1 
ATOM   9028  C  CA    . PRO B 2 275  ? 133.051 96.601  149.495 1.00 63.32  ? 290  PRO B CA    1 
ATOM   9029  C  C     . PRO B 2 275  ? 132.070 95.469  149.740 1.00 63.32  ? 290  PRO B C     1 
ATOM   9030  O  O     . PRO B 2 275  ? 132.329 94.346  149.291 1.00 63.32  ? 290  PRO B O     1 
ATOM   9031  C  CB    . PRO B 2 275  ? 134.341 96.400  150.298 1.00 63.32  ? 290  PRO B CB    1 
ATOM   9032  C  CG    . PRO B 2 275  ? 134.104 97.160  151.556 1.00 63.32  ? 290  PRO B CG    1 
ATOM   9033  C  CD    . PRO B 2 275  ? 133.280 98.362  151.170 1.00 63.32  ? 290  PRO B CD    1 
ATOM   9034  N  N     . GLY B 2 276  ? 130.961 95.723  150.429 1.00 58.41  ? 291  GLY B N     1 
ATOM   9035  C  CA    . GLY B 2 276  ? 129.988 94.686  150.706 1.00 58.41  ? 291  GLY B CA    1 
ATOM   9036  C  C     . GLY B 2 276  ? 129.008 94.465  149.573 1.00 58.41  ? 291  GLY B C     1 
ATOM   9037  O  O     . GLY B 2 276  ? 129.408 94.297  148.417 1.00 58.41  ? 291  GLY B O     1 
ATOM   9038  N  N     . ASN B 2 277  ? 127.718 94.453  149.900 1.00 65.59  ? 292  ASN B N     1 
ATOM   9039  C  CA    . ASN B 2 277  ? 126.689 94.224  148.895 1.00 65.59  ? 292  ASN B CA    1 
ATOM   9040  C  C     . ASN B 2 277  ? 126.694 95.339  147.857 1.00 65.59  ? 292  ASN B C     1 
ATOM   9041  O  O     . ASN B 2 277  ? 126.946 96.506  148.172 1.00 65.59  ? 292  ASN B O     1 
ATOM   9042  C  CB    . ASN B 2 277  ? 125.317 94.127  149.565 1.00 65.59  ? 292  ASN B CB    1 
ATOM   9043  C  CG    . ASN B 2 277  ? 124.206 93.824  148.580 1.00 65.59  ? 292  ASN B CG    1 
ATOM   9044  O  OD1   . ASN B 2 277  ? 124.453 93.364  147.466 1.00 65.59  ? 292  ASN B OD1   1 
ATOM   9045  N  ND2   . ASN B 2 277  ? 122.970 94.079  148.991 1.00 65.59  ? 292  ASN B ND2   1 
ATOM   9046  N  N     . VAL B 2 278  ? 126.416 94.970  146.603 1.00 62.72  ? 293  VAL B N     1 
ATOM   9047  C  CA    . VAL B 2 278  ? 126.388 95.942  145.513 1.00 62.72  ? 293  VAL B CA    1 
ATOM   9048  C  C     . VAL B 2 278  ? 125.036 96.627  145.378 1.00 62.72  ? 293  VAL B C     1 
ATOM   9049  O  O     . VAL B 2 278  ? 124.939 97.656  144.690 1.00 62.72  ? 293  VAL B O     1 
ATOM   9050  C  CB    . VAL B 2 278  ? 126.765 95.274  144.175 1.00 62.72  ? 293  VAL B CB    1 
ATOM   9051  C  CG1   . VAL B 2 278  ? 127.347 96.298  143.207 1.00 62.72  ? 293  VAL B CG1   1 
ATOM   9052  C  CG2   . VAL B 2 278  ? 127.744 94.134  144.408 1.00 62.72  ? 293  VAL B CG2   1 
ATOM   9053  N  N     . SER B 2 279  ? 123.987 96.097  146.013 1.00 58.15  ? 294  SER B N     1 
ATOM   9054  C  CA    . SER B 2 279  ? 122.686 96.754  145.959 1.00 58.15  ? 294  SER B CA    1 
ATOM   9055  C  C     . SER B 2 279  ? 122.706 98.102  146.666 1.00 58.15  ? 294  SER B C     1 
ATOM   9056  O  O     . SER B 2 279  ? 121.905 98.985  146.338 1.00 58.15  ? 294  SER B O     1 
ATOM   9057  C  CB    . SER B 2 279  ? 121.613 95.853  146.568 1.00 58.15  ? 294  SER B CB    1 
ATOM   9058  O  OG    . SER B 2 279  ? 120.349 96.493  146.561 1.00 58.15  ? 294  SER B OG    1 
ATOM   9059  N  N     . THR B 2 280  ? 123.602 98.277  147.641 1.00 58.40  ? 295  THR B N     1 
ATOM   9060  C  CA    . THR B 2 280  ? 123.717 99.564  148.319 1.00 58.40  ? 295  THR B CA    1 
ATOM   9061  C  C     . THR B 2 280  ? 124.165 100.655 147.356 1.00 58.40  ? 295  THR B C     1 
ATOM   9062  O  O     . THR B 2 280  ? 123.659 101.782 147.402 1.00 58.40  ? 295  THR B O     1 
ATOM   9063  C  CB    . THR B 2 280  ? 124.690 99.456  149.493 1.00 58.40  ? 295  THR B CB    1 
ATOM   9064  O  OG1   . THR B 2 280  ? 126.004 99.163  149.002 1.00 58.40  ? 295  THR B OG1   1 
ATOM   9065  C  CG2   . THR B 2 280  ? 124.254 98.351  150.444 1.00 58.40  ? 295  THR B CG2   1 
ATOM   9066  N  N     . ILE B 2 281  ? 125.112 100.340 146.478 1.00 59.30  ? 296  ILE B N     1 
ATOM   9067  C  CA    . ILE B 2 281  ? 125.604 101.299 145.497 1.00 59.30  ? 296  ILE B CA    1 
ATOM   9068  C  C     . ILE B 2 281  ? 124.865 101.142 144.174 1.00 59.30  ? 296  ILE B C     1 
ATOM   9069  O  O     . ILE B 2 281  ? 124.918 102.023 143.316 1.00 59.30  ? 296  ILE B O     1 
ATOM   9070  C  CB    . ILE B 2 281  ? 127.120 101.152 145.292 1.00 59.30  ? 296  ILE B CB    1 
ATOM   9071  C  CG1   . ILE B 2 281  ? 127.493 99.679  145.118 1.00 59.30  ? 296  ILE B CG1   1 
ATOM   9072  C  CG2   . ILE B 2 281  ? 127.875 101.772 146.453 1.00 59.30  ? 296  ILE B CG2   1 
ATOM   9073  C  CD1   . ILE B 2 281  ? 128.979 99.437  144.973 1.00 59.30  ? 296  ILE B CD1   1 
ATOM   9074  N  N     . ASN B 2 289  ? 119.130 101.257 137.436 1.00 54.81  ? 304  ASN B N     1 
ATOM   9075  C  CA    . ASN B 2 289  ? 119.904 100.872 138.610 1.00 54.81  ? 304  ASN B CA    1 
ATOM   9076  C  C     . ASN B 2 289  ? 121.379 100.700 138.267 1.00 54.81  ? 304  ASN B C     1 
ATOM   9077  O  O     . ASN B 2 289  ? 122.038 99.788  138.763 1.00 54.81  ? 304  ASN B O     1 
ATOM   9078  C  CB    . ASN B 2 289  ? 119.354 99.579  139.218 1.00 54.81  ? 304  ASN B CB    1 
ATOM   9079  C  CG    . ASN B 2 289  ? 117.939 99.734  139.734 1.00 54.81  ? 304  ASN B CG    1 
ATOM   9080  O  OD1   . ASN B 2 289  ? 117.518 100.830 140.103 1.00 54.81  ? 304  ASN B OD1   1 
ATOM   9081  N  ND2   . ASN B 2 289  ? 117.195 98.634  139.764 1.00 54.81  ? 304  ASN B ND2   1 
ATOM   9082  N  N     . VAL B 2 290  ? 121.891 101.586 137.414 1.00 52.08  ? 305  VAL B N     1 
ATOM   9083  C  CA    . VAL B 2 290  ? 123.296 101.531 137.033 1.00 52.08  ? 305  VAL B CA    1 
ATOM   9084  C  C     . VAL B 2 290  ? 124.154 102.000 138.199 1.00 52.08  ? 305  VAL B C     1 
ATOM   9085  O  O     . VAL B 2 290  ? 123.931 103.082 138.758 1.00 52.08  ? 305  VAL B O     1 
ATOM   9086  C  CB    . VAL B 2 290  ? 123.549 102.384 135.781 1.00 52.08  ? 305  VAL B CB    1 
ATOM   9087  C  CG1   . VAL B 2 290  ? 125.040 102.486 135.498 1.00 52.08  ? 305  VAL B CG1   1 
ATOM   9088  C  CG2   . VAL B 2 290  ? 122.813 101.801 134.586 1.00 52.08  ? 305  VAL B CG2   1 
ATOM   9089  N  N     . VAL B 2 291  ? 125.128 101.181 138.582 1.00 49.52  ? 306  VAL B N     1 
ATOM   9090  C  CA    . VAL B 2 291  ? 126.111 101.577 139.586 1.00 49.52  ? 306  VAL B CA    1 
ATOM   9091  C  C     . VAL B 2 291  ? 126.879 102.763 139.020 1.00 49.52  ? 306  VAL B C     1 
ATOM   9092  O  O     . VAL B 2 291  ? 127.684 102.595 138.093 1.00 49.52  ? 306  VAL B O     1 
ATOM   9093  C  CB    . VAL B 2 291  ? 127.046 100.415 139.951 1.00 49.52  ? 306  VAL B CB    1 
ATOM   9094  C  CG1   . VAL B 2 291  ? 128.048 100.856 141.002 1.00 49.52  ? 306  VAL B CG1   1 
ATOM   9095  C  CG2   . VAL B 2 291  ? 126.238 99.226  140.444 1.00 49.52  ? 306  VAL B CG2   1 
ATOM   9096  N  N     . PRO B 2 292  ? 126.670 103.968 139.543 1.00 40.43  ? 307  PRO B N     1 
ATOM   9097  C  CA    . PRO B 2 292  ? 127.177 105.164 138.867 1.00 40.43  ? 307  PRO B CA    1 
ATOM   9098  C  C     . PRO B 2 292  ? 128.691 105.265 138.931 1.00 40.43  ? 307  PRO B C     1 
ATOM   9099  O  O     . PRO B 2 292  ? 129.351 104.685 139.795 1.00 40.43  ? 307  PRO B O     1 
ATOM   9100  C  CB    . PRO B 2 292  ? 126.514 106.309 139.636 1.00 40.43  ? 307  PRO B CB    1 
ATOM   9101  C  CG    . PRO B 2 292  ? 126.343 105.763 141.003 1.00 40.43  ? 307  PRO B CG    1 
ATOM   9102  C  CD    . PRO B 2 292  ? 126.035 104.295 140.831 1.00 40.43  ? 307  PRO B CD    1 
ATOM   9103  N  N     . CYS B 2 293  ? 129.241 106.012 137.978 1.00 35.06  ? 308  CYS B N     1 
ATOM   9104  C  CA    . CYS B 2 293  ? 130.644 106.390 138.032 1.00 35.06  ? 308  CYS B CA    1 
ATOM   9105  C  C     . CYS B 2 293  ? 130.799 107.602 138.938 1.00 35.06  ? 308  CYS B C     1 
ATOM   9106  O  O     . CYS B 2 293  ? 129.842 108.013 139.601 1.00 35.06  ? 308  CYS B O     1 
ATOM   9107  C  CB    . CYS B 2 293  ? 131.181 106.690 136.634 1.00 35.06  ? 308  CYS B CB    1 
ATOM   9108  S  SG    . CYS B 2 293  ? 130.515 108.195 135.904 1.00 35.06  ? 308  CYS B SG    1 
ATOM   9109  N  N     . VAL B 2 294  ? 131.996 108.180 138.978 1.00 32.19  ? 309  VAL B N     1 
ATOM   9110  C  CA    . VAL B 2 294  ? 132.267 109.351 139.800 1.00 32.19  ? 309  VAL B CA    1 
ATOM   9111  C  C     . VAL B 2 294  ? 133.126 110.306 138.988 1.00 32.19  ? 309  VAL B C     1 
ATOM   9112  O  O     . VAL B 2 294  ? 134.093 109.897 138.342 1.00 32.19  ? 309  VAL B O     1 
ATOM   9113  C  CB    . VAL B 2 294  ? 132.964 108.963 141.126 1.00 32.19  ? 309  VAL B CB    1 
ATOM   9114  C  CG1   . VAL B 2 294  ? 133.375 110.200 141.895 1.00 32.19  ? 309  VAL B CG1   1 
ATOM   9115  C  CG2   . VAL B 2 294  ? 132.059 108.084 141.977 1.00 32.19  ? 309  VAL B CG2   1 
ATOM   9116  N  N     . LEU B 2 295  ? 132.776 111.591 139.028 1.00 27.80  ? 310  LEU B N     1 
ATOM   9117  C  CA    . LEU B 2 295  ? 133.506 112.600 138.270 1.00 27.80  ? 310  LEU B CA    1 
ATOM   9118  C  C     . LEU B 2 295  ? 134.478 113.410 139.109 1.00 27.80  ? 310  LEU B C     1 
ATOM   9119  O  O     . LEU B 2 295  ? 135.460 113.915 138.566 1.00 27.80  ? 310  LEU B O     1 
ATOM   9120  C  CB    . LEU B 2 295  ? 132.534 113.555 137.568 1.00 27.80  ? 310  LEU B CB    1 
ATOM   9121  C  CG    . LEU B 2 295  ? 131.624 112.906 136.523 1.00 27.80  ? 310  LEU B CG    1 
ATOM   9122  C  CD1   . LEU B 2 295  ? 130.970 113.952 135.633 1.00 27.80  ? 310  LEU B CD1   1 
ATOM   9123  C  CD2   . LEU B 2 295  ? 132.404 111.906 135.690 1.00 27.80  ? 310  LEU B CD2   1 
ATOM   9124  N  N     . SER B 2 296  ? 134.222 113.557 140.408 1.00 23.48  ? 311  SER B N     1 
ATOM   9125  C  CA    . SER B 2 296  ? 135.189 114.115 141.352 1.00 23.48  ? 311  SER B CA    1 
ATOM   9126  C  C     . SER B 2 296  ? 135.726 115.471 140.889 1.00 23.48  ? 311  SER B C     1 
ATOM   9127  O  O     . SER B 2 296  ? 136.918 115.646 140.636 1.00 23.48  ? 311  SER B O     1 
ATOM   9128  C  CB    . SER B 2 296  ? 136.337 113.131 141.588 1.00 23.48  ? 311  SER B CB    1 
ATOM   9129  O  OG    . SER B 2 296  ? 137.420 113.768 142.240 1.00 23.48  ? 311  SER B OG    1 
ATOM   9130  N  N     . VAL B 2 297  ? 134.818 116.433 140.781 1.00 18.44  ? 312  VAL B N     1 
ATOM   9131  C  CA    . VAL B 2 297  ? 135.206 117.812 140.508 1.00 18.44  ? 312  VAL B CA    1 
ATOM   9132  C  C     . VAL B 2 297  ? 135.677 118.431 141.817 1.00 18.44  ? 312  VAL B C     1 
ATOM   9133  O  O     . VAL B 2 297  ? 134.931 118.464 142.800 1.00 18.44  ? 312  VAL B O     1 
ATOM   9134  C  CB    . VAL B 2 297  ? 134.040 118.608 139.909 1.00 18.44  ? 312  VAL B CB    1 
ATOM   9135  C  CG1   . VAL B 2 297  ? 134.540 119.915 139.322 1.00 18.44  ? 312  VAL B CG1   1 
ATOM   9136  C  CG2   . VAL B 2 297  ? 133.315 117.780 138.863 1.00 18.44  ? 312  VAL B CG2   1 
ATOM   9137  N  N     . SER B 2 298  ? 136.933 118.878 141.833 1.00 15.21  ? 313  SER B N     1 
ATOM   9138  C  CA    . SER B 2 298  ? 137.522 119.425 143.053 1.00 15.21  ? 313  SER B CA    1 
ATOM   9139  C  C     . SER B 2 298  ? 138.379 120.644 142.825 1.00 15.21  ? 313  SER B C     1 
ATOM   9140  O  O     . SER B 2 298  ? 139.457 120.533 142.262 1.00 15.21  ? 313  SER B O     1 
ATOM   9141  C  CB    . SER B 2 298  ? 138.387 118.371 143.704 1.00 15.21  ? 313  SER B CB    1 
ATOM   9142  O  OG    . SER B 2 298  ? 139.367 118.974 144.527 1.00 15.21  ? 313  SER B OG    1 
ATOM   9143  N  N     . GLY B 2 299  ? 137.932 121.799 143.286 1.00 14.87  ? 314  GLY B N     1 
ATOM   9144  C  CA    . GLY B 2 299  ? 138.639 123.061 143.114 1.00 14.87  ? 314  GLY B CA    1 
ATOM   9145  C  C     . GLY B 2 299  ? 139.246 123.514 144.429 1.00 14.87  ? 314  GLY B C     1 
ATOM   9146  O  O     . GLY B 2 299  ? 138.671 123.291 145.496 1.00 14.87  ? 314  GLY B O     1 
ATOM   9147  N  N     . ASP B 2 300  ? 140.407 124.155 144.343 1.00 17.32  ? 315  ASP B N     1 
ATOM   9148  C  CA    . ASP B 2 300  ? 141.136 124.633 145.513 1.00 17.32  ? 315  ASP B CA    1 
ATOM   9149  C  C     . ASP B 2 300  ? 140.814 126.110 145.710 1.00 17.32  ? 315  ASP B C     1 
ATOM   9150  O  O     . ASP B 2 300  ? 141.314 126.964 144.970 1.00 17.32  ? 315  ASP B O     1 
ATOM   9151  C  CB    . ASP B 2 300  ? 142.638 124.414 145.338 1.00 17.32  ? 315  ASP B CB    1 
ATOM   9152  C  CG    . ASP B 2 300  ? 143.420 124.667 146.613 1.00 17.32  ? 315  ASP B CG    1 
ATOM   9153  O  OD1   . ASP B 2 300  ? 142.796 124.856 147.678 1.00 17.32  ? 315  ASP B OD1   1 
ATOM   9154  O  OD2   . ASP B 2 300  ? 144.667 124.676 146.547 1.00 17.32  ? 315  ASP B OD2   1 
ATOM   9155  N  N     . VAL B 2 301  ? 139.987 126.412 146.714 1.00 17.31  ? 316  VAL B N     1 
ATOM   9156  C  CA    . VAL B 2 301  ? 139.556 127.792 146.903 1.00 17.31  ? 316  VAL B CA    1 
ATOM   9157  C  C     . VAL B 2 301  ? 140.621 128.643 147.580 1.00 17.31  ? 316  VAL B C     1 
ATOM   9158  O  O     . VAL B 2 301  ? 140.552 129.871 147.497 1.00 17.31  ? 316  VAL B O     1 
ATOM   9159  C  CB    . VAL B 2 301  ? 138.240 127.874 147.695 1.00 17.31  ? 316  VAL B CB    1 
ATOM   9160  C  CG1   . VAL B 2 301  ? 137.263 126.823 147.210 1.00 17.31  ? 316  VAL B CG1   1 
ATOM   9161  C  CG2   . VAL B 2 301  ? 138.496 127.740 149.175 1.00 17.31  ? 316  VAL B CG2   1 
ATOM   9162  N  N     . ASP B 2 302  ? 141.604 128.038 148.249 1.00 18.72  ? 317  ASP B N     1 
ATOM   9163  C  CA    . ASP B 2 302  ? 142.768 128.810 148.675 1.00 18.72  ? 317  ASP B CA    1 
ATOM   9164  C  C     . ASP B 2 302  ? 143.613 129.202 147.471 1.00 18.72  ? 317  ASP B C     1 
ATOM   9165  O  O     . ASP B 2 302  ? 143.963 130.377 147.288 1.00 18.72  ? 317  ASP B O     1 
ATOM   9166  C  CB    . ASP B 2 302  ? 143.599 128.007 149.673 1.00 18.72  ? 317  ASP B CB    1 
ATOM   9167  C  CG    . ASP B 2 302  ? 142.868 127.753 150.974 1.00 18.72  ? 317  ASP B CG    1 
ATOM   9168  O  OD1   . ASP B 2 302  ? 142.216 128.684 151.484 1.00 18.72  ? 317  ASP B OD1   1 
ATOM   9169  O  OD2   . ASP B 2 302  ? 142.945 126.621 151.488 1.00 18.72  ? 317  ASP B OD2   1 
ATOM   9170  N  N     . LEU B 2 303  ? 143.920 128.227 146.615 1.00 13.92  ? 318  LEU B N     1 
ATOM   9171  C  CA    . LEU B 2 303  ? 144.620 128.525 145.376 1.00 13.92  ? 318  LEU B CA    1 
ATOM   9172  C  C     . LEU B 2 303  ? 143.757 129.359 144.444 1.00 13.92  ? 318  LEU B C     1 
ATOM   9173  O  O     . LEU B 2 303  ? 144.278 130.212 143.725 1.00 13.92  ? 318  LEU B O     1 
ATOM   9174  C  CB    . LEU B 2 303  ? 145.059 127.229 144.695 1.00 13.92  ? 318  LEU B CB    1 
ATOM   9175  C  CG    . LEU B 2 303  ? 146.145 127.359 143.629 1.00 13.92  ? 318  LEU B CG    1 
ATOM   9176  C  CD1   . LEU B 2 303  ? 147.264 128.245 144.134 1.00 13.92  ? 318  LEU B CD1   1 
ATOM   9177  C  CD2   . LEU B 2 303  ? 146.679 125.989 143.254 1.00 13.92  ? 318  LEU B CD2   1 
ATOM   9178  N  N     . GLY B 2 304  ? 142.441 129.140 144.447 1.00 11.84  ? 319  GLY B N     1 
ATOM   9179  C  CA    . GLY B 2 304  ? 141.561 129.997 143.667 1.00 11.84  ? 319  GLY B CA    1 
ATOM   9180  C  C     . GLY B 2 304  ? 141.555 131.433 144.158 1.00 11.84  ? 319  GLY B C     1 
ATOM   9181  O  O     . GLY B 2 304  ? 141.541 132.373 143.360 1.00 11.84  ? 319  GLY B O     1 
ATOM   9182  N  N     . THR B 2 305  ? 141.553 131.620 145.479 1.00 15.79  ? 320  THR B N     1 
ATOM   9183  C  CA    . THR B 2 305  ? 141.620 132.960 146.047 1.00 15.79  ? 320  THR B CA    1 
ATOM   9184  C  C     . THR B 2 305  ? 142.924 133.646 145.673 1.00 15.79  ? 320  THR B C     1 
ATOM   9185  O  O     . THR B 2 305  ? 142.937 134.831 145.318 1.00 15.79  ? 320  THR B O     1 
ATOM   9186  C  CB    . THR B 2 305  ? 141.465 132.882 147.564 1.00 15.79  ? 320  THR B CB    1 
ATOM   9187  O  OG1   . THR B 2 305  ? 140.213 132.265 147.883 1.00 15.79  ? 320  THR B OG1   1 
ATOM   9188  C  CG2   . THR B 2 305  ? 141.512 134.261 148.180 1.00 15.79  ? 320  THR B CG2   1 
ATOM   9189  N  N     . LEU B 2 306  ? 144.035 132.912 145.730 1.00 16.71  ? 321  LEU B N     1 
ATOM   9190  C  CA    . LEU B 2 306  ? 145.302 133.490 145.290 1.00 16.71  ? 321  LEU B CA    1 
ATOM   9191  C  C     . LEU B 2 306  ? 145.296 133.766 143.789 1.00 16.71  ? 321  LEU B C     1 
ATOM   9192  O  O     . LEU B 2 306  ? 145.897 134.746 143.335 1.00 16.71  ? 321  LEU B O     1 
ATOM   9193  C  CB    . LEU B 2 306  ? 146.454 132.564 145.680 1.00 16.71  ? 321  LEU B CB    1 
ATOM   9194  C  CG    . LEU B 2 306  ? 147.884 132.991 145.348 1.00 16.71  ? 321  LEU B CG    1 
ATOM   9195  C  CD1   . LEU B 2 306  ? 148.102 134.455 145.659 1.00 16.71  ? 321  LEU B CD1   1 
ATOM   9196  C  CD2   . LEU B 2 306  ? 148.870 132.134 146.121 1.00 16.71  ? 321  LEU B CD2   1 
ATOM   9197  N  N     . ALA B 2 307  ? 144.602 132.933 143.011 1.00 14.05  ? 322  ALA B N     1 
ATOM   9198  C  CA    . ALA B 2 307  ? 144.479 133.174 141.579 1.00 14.05  ? 322  ALA B CA    1 
ATOM   9199  C  C     . ALA B 2 307  ? 143.733 134.467 141.303 1.00 14.05  ? 322  ALA B C     1 
ATOM   9200  O  O     . ALA B 2 307  ? 144.129 135.246 140.432 1.00 14.05  ? 322  ALA B O     1 
ATOM   9201  C  CB    . ALA B 2 307  ? 143.767 132.000 140.910 1.00 14.05  ? 322  ALA B CB    1 
ATOM   9202  N  N     . TYR B 2 308  ? 142.643 134.707 142.029 1.00 14.26  ? 323  TYR B N     1 
ATOM   9203  C  CA    . TYR B 2 308  ? 141.870 135.931 141.859 1.00 14.26  ? 323  TYR B CA    1 
ATOM   9204  C  C     . TYR B 2 308  ? 142.560 137.147 142.452 1.00 14.26  ? 323  TYR B C     1 
ATOM   9205  O  O     . TYR B 2 308  ? 142.243 138.273 142.061 1.00 14.26  ? 323  TYR B O     1 
ATOM   9206  C  CB    . TYR B 2 308  ? 140.487 135.768 142.481 1.00 14.26  ? 323  TYR B CB    1 
ATOM   9207  C  CG    . TYR B 2 308  ? 139.537 135.015 141.590 1.00 14.26  ? 323  TYR B CG    1 
ATOM   9208  C  CD1   . TYR B 2 308  ? 139.570 135.189 140.221 1.00 14.26  ? 323  TYR B CD1   1 
ATOM   9209  C  CD2   . TYR B 2 308  ? 138.620 134.123 142.112 1.00 14.26  ? 323  TYR B CD2   1 
ATOM   9210  C  CE1   . TYR B 2 308  ? 138.714 134.508 139.398 1.00 14.26  ? 323  TYR B CE1   1 
ATOM   9211  C  CE2   . TYR B 2 308  ? 137.760 133.435 141.292 1.00 14.26  ? 323  TYR B CE2   1 
ATOM   9212  C  CZ    . TYR B 2 308  ? 137.812 133.633 139.936 1.00 14.26  ? 323  TYR B CZ    1 
ATOM   9213  O  OH    . TYR B 2 308  ? 136.955 132.951 139.110 1.00 14.26  ? 323  TYR B OH    1 
ATOM   9214  N  N     . LEU B 2 309  ? 143.478 136.949 143.395 1.00 17.12  ? 324  LEU B N     1 
ATOM   9215  C  CA    . LEU B 2 309  ? 144.301 138.056 143.863 1.00 17.12  ? 324  LEU B CA    1 
ATOM   9216  C  C     . LEU B 2 309  ? 145.397 138.405 142.868 1.00 17.12  ? 324  LEU B C     1 
ATOM   9217  O  O     . LEU B 2 309  ? 145.790 139.570 142.771 1.00 17.12  ? 324  LEU B O     1 
ATOM   9218  C  CB    . LEU B 2 309  ? 144.920 137.721 145.219 1.00 17.12  ? 324  LEU B CB    1 
ATOM   9219  C  CG    . LEU B 2 309  ? 144.036 137.852 146.455 1.00 17.12  ? 324  LEU B CG    1 
ATOM   9220  C  CD1   . LEU B 2 309  ? 144.741 137.277 147.667 1.00 17.12  ? 324  LEU B CD1   1 
ATOM   9221  C  CD2   . LEU B 2 309  ? 143.704 139.309 146.677 1.00 17.12  ? 324  LEU B CD2   1 
ATOM   9222  N  N     . TYR B 2 310  ? 145.913 137.412 142.141 1.00 18.80  ? 325  TYR B N     1 
ATOM   9223  C  CA    . TYR B 2 310  ? 146.906 137.688 141.108 1.00 18.80  ? 325  TYR B CA    1 
ATOM   9224  C  C     . TYR B 2 310  ? 146.271 138.221 139.832 1.00 18.80  ? 325  TYR B C     1 
ATOM   9225  O  O     . TYR B 2 310  ? 146.877 139.040 139.135 1.00 18.80  ? 325  TYR B O     1 
ATOM   9226  C  CB    . TYR B 2 310  ? 147.724 136.428 140.804 1.00 18.80  ? 325  TYR B CB    1 
ATOM   9227  C  CG    . TYR B 2 310  ? 149.107 136.453 141.413 1.00 18.80  ? 325  TYR B CG    1 
ATOM   9228  C  CD1   . TYR B 2 310  ? 150.065 137.347 140.958 1.00 18.80  ? 325  TYR B CD1   1 
ATOM   9229  C  CD2   . TYR B 2 310  ? 149.453 135.593 142.446 1.00 18.80  ? 325  TYR B CD2   1 
ATOM   9230  C  CE1   . TYR B 2 310  ? 151.328 137.390 141.511 1.00 18.80  ? 325  TYR B CE1   1 
ATOM   9231  C  CE2   . TYR B 2 310  ? 150.719 135.626 143.006 1.00 18.80  ? 325  TYR B CE2   1 
ATOM   9232  C  CZ    . TYR B 2 310  ? 151.653 136.528 142.531 1.00 18.80  ? 325  TYR B CZ    1 
ATOM   9233  O  OH    . TYR B 2 310  ? 152.917 136.578 143.072 1.00 18.80  ? 325  TYR B OH    1 
ATOM   9234  N  N     . ASP B 2 311  ? 145.058 137.772 139.521 1.00 13.35  ? 326  ASP B N     1 
ATOM   9235  C  CA    . ASP B 2 311  ? 144.381 138.156 138.289 1.00 13.35  ? 326  ASP B CA    1 
ATOM   9236  C  C     . ASP B 2 311  ? 143.827 139.571 138.365 1.00 13.35  ? 326  ASP B C     1 
ATOM   9237  O  O     . ASP B 2 311  ? 143.864 140.308 137.375 1.00 13.35  ? 326  ASP B O     1 
ATOM   9238  C  CB    . ASP B 2 311  ? 143.264 137.156 137.997 1.00 13.35  ? 326  ASP B CB    1 
ATOM   9239  C  CG    . ASP B 2 311  ? 142.264 137.681 137.006 1.00 13.35  ? 326  ASP B CG    1 
ATOM   9240  O  OD1   . ASP B 2 311  ? 142.672 138.049 135.886 1.00 13.35  ? 326  ASP B OD1   1 
ATOM   9241  O  OD2   . ASP B 2 311  ? 141.067 137.723 137.346 1.00 13.35  ? 326  ASP B OD2   1 
ATOM   9242  N  N     . SER B 2 312  ? 143.306 139.960 139.531 1.00 14.98  ? 327  SER B N     1 
ATOM   9243  C  CA    . SER B 2 312  ? 142.771 141.305 139.698 1.00 14.98  ? 327  SER B CA    1 
ATOM   9244  C  C     . SER B 2 312  ? 143.860 142.354 139.532 1.00 14.98  ? 327  SER B C     1 
ATOM   9245  O  O     . SER B 2 312  ? 143.641 143.393 138.901 1.00 14.98  ? 327  SER B O     1 
ATOM   9246  C  CB    . SER B 2 312  ? 142.111 141.430 141.066 1.00 14.98  ? 327  SER B CB    1 
ATOM   9247  O  OG    . SER B 2 312  ? 143.027 141.105 142.093 1.00 14.98  ? 327  SER B OG    1 
ATOM   9248  N  N     . PHE B 2 313  ? 145.035 142.106 140.098 1.00 19.87  ? 328  PHE B N     1 
ATOM   9249  C  CA    . PHE B 2 313  ? 146.167 142.989 139.874 1.00 19.87  ? 328  PHE B CA    1 
ATOM   9250  C  C     . PHE B 2 313  ? 146.585 142.929 138.410 1.00 19.87  ? 328  PHE B C     1 
ATOM   9251  O  O     . PHE B 2 313  ? 146.498 141.880 137.768 1.00 19.87  ? 328  PHE B O     1 
ATOM   9252  C  CB    . PHE B 2 313  ? 147.329 142.596 140.781 1.00 19.87  ? 328  PHE B CB    1 
ATOM   9253  C  CG    . PHE B 2 313  ? 148.280 143.718 141.065 1.00 19.87  ? 328  PHE B CG    1 
ATOM   9254  C  CD1   . PHE B 2 313  ? 147.979 144.671 142.020 1.00 19.87  ? 328  PHE B CD1   1 
ATOM   9255  C  CD2   . PHE B 2 313  ? 149.476 143.819 140.380 1.00 19.87  ? 328  PHE B CD2   1 
ATOM   9256  C  CE1   . PHE B 2 313  ? 148.850 145.705 142.284 1.00 19.87  ? 328  PHE B CE1   1 
ATOM   9257  C  CE2   . PHE B 2 313  ? 150.351 144.851 140.640 1.00 19.87  ? 328  PHE B CE2   1 
ATOM   9258  C  CZ    . PHE B 2 313  ? 150.037 145.796 141.594 1.00 19.87  ? 328  PHE B CZ    1 
ATOM   9259  N  N     . GLN B 2 314  ? 147.033 144.069 137.877 1.00 24.62  ? 329  GLN B N     1 
ATOM   9260  C  CA    . GLN B 2 314  ? 147.285 144.155 136.442 1.00 24.62  ? 329  GLN B CA    1 
ATOM   9261  C  C     . GLN B 2 314  ? 148.483 143.317 136.016 1.00 24.62  ? 329  GLN B C     1 
ATOM   9262  O  O     . GLN B 2 314  ? 148.553 142.896 134.856 1.00 24.62  ? 329  GLN B O     1 
ATOM   9263  C  CB    . GLN B 2 314  ? 147.485 145.613 136.022 1.00 24.62  ? 329  GLN B CB    1 
ATOM   9264  C  CG    . GLN B 2 314  ? 148.819 146.221 136.432 1.00 24.62  ? 329  GLN B CG    1 
ATOM   9265  C  CD    . GLN B 2 314  ? 148.740 146.993 137.734 1.00 24.62  ? 329  GLN B CD    1 
ATOM   9266  O  OE1   . GLN B 2 314  ? 147.679 147.087 138.351 1.00 24.62  ? 329  GLN B OE1   1 
ATOM   9267  N  NE2   . GLN B 2 314  ? 149.866 147.555 138.156 1.00 24.62  ? 329  GLN B NE2   1 
ATOM   9268  N  N     . LEU B 2 315  ? 149.425 143.068 136.923 1.00 25.77  ? 330  LEU B N     1 
ATOM   9269  C  CA    . LEU B 2 315  ? 150.646 142.321 136.613 1.00 25.77  ? 330  LEU B CA    1 
ATOM   9270  C  C     . LEU B 2 315  ? 151.403 142.930 135.436 1.00 25.77  ? 330  LEU B C     1 
ATOM   9271  O  O     . LEU B 2 315  ? 151.307 142.448 134.307 1.00 25.77  ? 330  LEU B O     1 
ATOM   9272  C  CB    . LEU B 2 315  ? 150.325 140.852 136.322 1.00 25.77  ? 330  LEU B CB    1 
ATOM   9273  C  CG    . LEU B 2 315  ? 149.808 140.016 137.493 1.00 25.77  ? 330  LEU B CG    1 
ATOM   9274  C  CD1   . LEU B 2 315  ? 149.459 138.609 137.035 1.00 25.77  ? 330  LEU B CD1   1 
ATOM   9275  C  CD2   . LEU B 2 315  ? 150.837 139.980 138.610 1.00 25.77  ? 330  LEU B CD2   1 
ATOM   9276  N  N     . GLN B 2 327  ? 150.226 154.103 136.510 1.00 33.89  ? 342  GLN B N     1 
ATOM   9277  C  CA    . GLN B 2 327  ? 148.886 153.650 136.864 1.00 33.89  ? 342  GLN B CA    1 
ATOM   9278  C  C     . GLN B 2 327  ? 148.606 153.827 138.347 1.00 33.89  ? 342  GLN B C     1 
ATOM   9279  O  O     . GLN B 2 327  ? 149.361 154.479 139.066 1.00 33.89  ? 342  GLN B O     1 
ATOM   9280  C  CB    . GLN B 2 327  ? 148.693 152.181 136.486 1.00 33.89  ? 342  GLN B CB    1 
ATOM   9281  C  CG    . GLN B 2 327  ? 148.574 151.916 135.000 1.00 33.89  ? 342  GLN B CG    1 
ATOM   9282  C  CD    . GLN B 2 327  ? 148.242 150.467 134.702 1.00 33.89  ? 342  GLN B CD    1 
ATOM   9283  O  OE1   . GLN B 2 327  ? 148.216 149.628 135.603 1.00 33.89  ? 342  GLN B OE1   1 
ATOM   9284  N  NE2   . GLN B 2 327  ? 147.983 150.167 133.435 1.00 33.89  ? 342  GLN B NE2   1 
ATOM   9285  N  N     . ARG B 2 328  ? 147.504 153.237 138.793 1.00 23.85  ? 343  ARG B N     1 
ATOM   9286  C  CA    . ARG B 2 328  ? 147.139 153.194 140.199 1.00 23.85  ? 343  ARG B CA    1 
ATOM   9287  C  C     . ARG B 2 328  ? 147.025 151.743 140.637 1.00 23.85  ? 343  ARG B C     1 
ATOM   9288  O  O     . ARG B 2 328  ? 146.481 150.905 139.909 1.00 23.85  ? 343  ARG B O     1 
ATOM   9289  C  CB    . ARG B 2 328  ? 145.818 153.925 140.457 1.00 23.85  ? 343  ARG B CB    1 
ATOM   9290  C  CG    . ARG B 2 328  ? 144.672 153.442 139.590 1.00 23.85  ? 343  ARG B CG    1 
ATOM   9291  C  CD    . ARG B 2 328  ? 143.343 153.549 140.309 1.00 23.85  ? 343  ARG B CD    1 
ATOM   9292  N  NE    . ARG B 2 328  ? 142.252 153.058 139.479 1.00 23.85  ? 343  ARG B NE    1 
ATOM   9293  C  CZ    . ARG B 2 328  ? 141.035 152.784 139.926 1.00 23.85  ? 343  ARG B CZ    1 
ATOM   9294  N  NH1   . ARG B 2 328  ? 140.720 152.928 141.201 1.00 23.85  ? 343  ARG B NH1   1 
ATOM   9295  N  NH2   . ARG B 2 328  ? 140.113 152.352 139.072 1.00 23.85  ? 343  ARG B NH2   1 
ATOM   9296  N  N     . LYS B 2 329  ? 147.550 151.443 141.819 1.00 22.01  ? 344  LYS B N     1 
ATOM   9297  C  CA    . LYS B 2 329  ? 147.453 150.097 142.362 1.00 22.01  ? 344  LYS B CA    1 
ATOM   9298  C  C     . LYS B 2 329  ? 146.025 149.851 142.822 1.00 22.01  ? 344  LYS B C     1 
ATOM   9299  O  O     . LYS B 2 329  ? 145.568 150.451 143.800 1.00 22.01  ? 344  LYS B O     1 
ATOM   9300  C  CB    . LYS B 2 329  ? 148.435 149.907 143.513 1.00 22.01  ? 344  LYS B CB    1 
ATOM   9301  C  CG    . LYS B 2 329  ? 149.882 149.931 143.084 1.00 22.01  ? 344  LYS B CG    1 
ATOM   9302  C  CD    . LYS B 2 329  ? 150.801 149.675 144.256 1.00 22.01  ? 344  LYS B CD    1 
ATOM   9303  C  CE    . LYS B 2 329  ? 152.251 149.698 143.816 1.00 22.01  ? 344  LYS B CE    1 
ATOM   9304  N  NZ    . LYS B 2 329  ? 152.530 148.652 142.792 1.00 22.01  ? 344  LYS B NZ    1 
ATOM   9305  N  N     . VAL B 2 330  ? 145.324 148.971 142.119 1.00 17.82  ? 345  VAL B N     1 
ATOM   9306  C  CA    . VAL B 2 330  ? 143.937 148.661 142.424 1.00 17.82  ? 345  VAL B CA    1 
ATOM   9307  C  C     . VAL B 2 330  ? 143.695 147.191 142.128 1.00 17.82  ? 345  VAL B C     1 
ATOM   9308  O  O     . VAL B 2 330  ? 144.090 146.675 141.079 1.00 17.82  ? 345  VAL B O     1 
ATOM   9309  C  CB    . VAL B 2 330  ? 142.967 149.554 141.619 1.00 17.82  ? 345  VAL B CB    1 
ATOM   9310  C  CG1   . VAL B 2 330  ? 143.439 149.684 140.184 1.00 17.82  ? 345  VAL B CG1   1 
ATOM   9311  C  CG2   . VAL B 2 330  ? 141.560 148.995 141.666 1.00 17.82  ? 345  VAL B CG2   1 
ATOM   9312  N  N     . LEU B 2 331  ? 143.051 146.512 143.065 1.00 16.48  ? 346  LEU B N     1 
ATOM   9313  C  CA    . LEU B 2 331  ? 142.636 145.128 142.880 1.00 16.48  ? 346  LEU B CA    1 
ATOM   9314  C  C     . LEU B 2 331  ? 141.238 145.168 142.273 1.00 16.48  ? 346  LEU B C     1 
ATOM   9315  O  O     . LEU B 2 331  ? 140.245 145.336 142.979 1.00 16.48  ? 346  LEU B O     1 
ATOM   9316  C  CB    . LEU B 2 331  ? 142.655 144.349 144.187 1.00 16.48  ? 346  LEU B CB    1 
ATOM   9317  C  CG    . LEU B 2 331  ? 144.000 144.116 144.869 1.00 16.48  ? 346  LEU B CG    1 
ATOM   9318  C  CD1   . LEU B 2 331  ? 143.871 143.007 145.896 1.00 16.48  ? 346  LEU B CD1   1 
ATOM   9319  C  CD2   . LEU B 2 331  ? 145.072 143.786 143.851 1.00 16.48  ? 346  LEU B CD2   1 
ATOM   9320  N  N     . LYS B 2 332  ? 141.166 144.996 140.956 1.00 11.14  ? 347  LYS B N     1 
ATOM   9321  C  CA    . LYS B 2 332  ? 139.886 145.037 140.264 1.00 11.14  ? 347  LYS B CA    1 
ATOM   9322  C  C     . LYS B 2 332  ? 139.115 143.750 140.502 1.00 11.14  ? 347  LYS B C     1 
ATOM   9323  O  O     . LYS B 2 332  ? 138.765 143.043 139.555 1.00 11.14  ? 347  LYS B O     1 
ATOM   9324  C  CB    . LYS B 2 332  ? 140.090 145.252 138.764 1.00 11.14  ? 347  LYS B CB    1 
ATOM   9325  C  CG    . LYS B 2 332  ? 140.583 146.634 138.390 1.00 11.14  ? 347  LYS B CG    1 
ATOM   9326  C  CD    . LYS B 2 332  ? 139.564 147.691 138.759 1.00 11.14  ? 347  LYS B CD    1 
ATOM   9327  C  CE    . LYS B 2 332  ? 139.926 149.032 138.158 1.00 11.14  ? 347  LYS B CE    1 
ATOM   9328  N  NZ    . LYS B 2 332  ? 139.882 148.998 136.671 1.00 11.14  ? 347  LYS B NZ    1 
ATOM   9329  N  N     . LEU B 2 333  ? 138.859 143.450 141.751 1.00 15.84  ? 348  LEU B N     1 
ATOM   9330  C  CA    . LEU B 2 333  ? 138.090 142.264 142.050 1.00 15.84  ? 348  LEU B CA    1 
ATOM   9331  C  C     . LEU B 2 333  ? 136.619 142.416 141.705 1.00 15.84  ? 348  LEU B C     1 
ATOM   9332  O  O     . LEU B 2 333  ? 136.056 143.496 141.794 1.00 15.84  ? 348  LEU B O     1 
ATOM   9333  C  CB    . LEU B 2 333  ? 138.255 141.868 143.521 1.00 15.84  ? 348  LEU B CB    1 
ATOM   9334  C  CG    . LEU B 2 333  ? 139.452 141.017 143.935 1.00 15.84  ? 348  LEU B CG    1 
ATOM   9335  C  CD1   . LEU B 2 333  ? 140.431 141.847 144.744 1.00 15.84  ? 348  LEU B CD1   1 
ATOM   9336  C  CD2   . LEU B 2 333  ? 138.965 139.837 144.756 1.00 15.84  ? 348  LEU B CD2   1 
ATOM   9337  N  N     . HIS B 2 334  ? 135.984 141.322 141.337 1.00 18.81  ? 349  HIS B N     1 
ATOM   9338  C  CA    . HIS B 2 334  ? 134.598 141.368 140.911 1.00 18.81  ? 349  HIS B CA    1 
ATOM   9339  C  C     . HIS B 2 334  ? 133.733 141.925 142.038 1.00 18.81  ? 349  HIS B C     1 
ATOM   9340  O  O     . HIS B 2 334  ? 133.973 141.620 143.213 1.00 18.81  ? 349  HIS B O     1 
ATOM   9341  C  CB    . HIS B 2 334  ? 134.121 139.973 140.515 1.00 18.81  ? 349  HIS B CB    1 
ATOM   9342  C  CG    . HIS B 2 334  ? 132.877 139.968 139.685 1.00 18.81  ? 349  HIS B CG    1 
ATOM   9343  N  ND1   . HIS B 2 334  ? 131.772 139.212 140.007 1.00 18.81  ? 349  HIS B ND1   1 
ATOM   9344  C  CD2   . HIS B 2 334  ? 132.568 140.616 138.538 1.00 18.81  ? 349  HIS B CD2   1 
ATOM   9345  C  CE1   . HIS B 2 334  ? 130.833 139.396 139.096 1.00 18.81  ? 349  HIS B CE1   1 
ATOM   9346  N  NE2   . HIS B 2 334  ? 131.291 140.246 138.195 1.00 18.81  ? 349  HIS B NE2   1 
ATOM   9347  N  N     . PRO B 2 335  ? 132.741 142.763 141.724 1.00 21.13  ? 350  PRO B N     1 
ATOM   9348  C  CA    . PRO B 2 335  ? 131.832 143.258 142.770 1.00 21.13  ? 350  PRO B CA    1 
ATOM   9349  C  C     . PRO B 2 335  ? 131.154 142.164 143.575 1.00 21.13  ? 350  PRO B C     1 
ATOM   9350  O  O     . PRO B 2 335  ? 130.607 142.458 144.643 1.00 21.13  ? 350  PRO B O     1 
ATOM   9351  C  CB    . PRO B 2 335  ? 130.816 144.083 141.974 1.00 21.13  ? 350  PRO B CB    1 
ATOM   9352  C  CG    . PRO B 2 335  ? 131.602 144.587 140.815 1.00 21.13  ? 350  PRO B CG    1 
ATOM   9353  C  CD    . PRO B 2 335  ? 132.551 143.478 140.450 1.00 21.13  ? 350  PRO B CD    1 
ATOM   9354  N  N     . CYS B 2 336  ? 131.162 140.920 143.102 1.00 20.05  ? 351  CYS B N     1 
ATOM   9355  C  CA    . CYS B 2 336  ? 130.618 139.805 143.862 1.00 20.05  ? 351  CYS B CA    1 
ATOM   9356  C  C     . CYS B 2 336  ? 131.664 139.098 144.712 1.00 20.05  ? 351  CYS B C     1 
ATOM   9357  O  O     . CYS B 2 336  ? 131.309 138.194 145.474 1.00 20.05  ? 351  CYS B O     1 
ATOM   9358  C  CB    . CYS B 2 336  ? 129.968 138.794 142.918 1.00 20.05  ? 351  CYS B CB    1 
ATOM   9359  S  SG    . CYS B 2 336  ? 128.778 139.527 141.785 1.00 20.05  ? 351  CYS B SG    1 
ATOM   9360  N  N     . LEU B 2 337  ? 132.935 139.482 144.592 1.00 17.04  ? 352  LEU B N     1 
ATOM   9361  C  CA    . LEU B 2 337  ? 134.011 138.906 145.383 1.00 17.04  ? 352  LEU B CA    1 
ATOM   9362  C  C     . LEU B 2 337  ? 134.707 139.901 146.293 1.00 17.04  ? 352  LEU B C     1 
ATOM   9363  O  O     . LEU B 2 337  ? 135.361 139.473 147.249 1.00 17.04  ? 352  LEU B O     1 
ATOM   9364  C  CB    . LEU B 2 337  ? 135.076 138.272 144.475 1.00 17.04  ? 352  LEU B CB    1 
ATOM   9365  C  CG    . LEU B 2 337  ? 134.704 137.061 143.626 1.00 17.04  ? 352  LEU B CG    1 
ATOM   9366  C  CD1   . LEU B 2 337  ? 135.924 136.596 142.868 1.00 17.04  ? 352  LEU B CD1   1 
ATOM   9367  C  CD2   . LEU B 2 337  ? 134.149 135.950 144.493 1.00 17.04  ? 352  LEU B CD2   1 
ATOM   9368  N  N     . ALA B 2 338  ? 134.602 141.197 146.020 1.00 22.81  ? 353  ALA B N     1 
ATOM   9369  C  CA    . ALA B 2 338  ? 135.299 142.184 146.830 1.00 22.81  ? 353  ALA B CA    1 
ATOM   9370  C  C     . ALA B 2 338  ? 134.872 142.060 148.290 1.00 22.81  ? 353  ALA B C     1 
ATOM   9371  O  O     . ALA B 2 338  ? 133.680 141.894 148.578 1.00 22.81  ? 353  ALA B O     1 
ATOM   9372  C  CB    . ALA B 2 338  ? 135.016 143.597 146.317 1.00 22.81  ? 353  ALA B CB    1 
ATOM   9373  N  N     . PRO B 2 339  ? 135.813 142.118 149.235 1.00 18.25  ? 354  PRO B N     1 
ATOM   9374  C  CA    . PRO B 2 339  ? 135.421 141.976 150.645 1.00 18.25  ? 354  PRO B CA    1 
ATOM   9375  C  C     . PRO B 2 339  ? 134.727 143.206 151.198 1.00 18.25  ? 354  PRO B C     1 
ATOM   9376  O  O     . PRO B 2 339  ? 133.801 143.079 152.008 1.00 18.25  ? 354  PRO B O     1 
ATOM   9377  C  CB    . PRO B 2 339  ? 136.759 141.710 151.344 1.00 18.25  ? 354  PRO B CB    1 
ATOM   9378  C  CG    . PRO B 2 339  ? 137.757 142.411 150.493 1.00 18.25  ? 354  PRO B CG    1 
ATOM   9379  C  CD    . PRO B 2 339  ? 137.270 142.273 149.078 1.00 18.25  ? 354  PRO B CD    1 
ATOM   9380  N  N     . ILE B 2 340  ? 135.153 144.395 150.781 1.00 23.19  ? 355  ILE B N     1 
ATOM   9381  C  CA    . ILE B 2 340  ? 134.623 145.663 151.268 1.00 23.19  ? 355  ILE B CA    1 
ATOM   9382  C  C     . ILE B 2 340  ? 133.979 146.381 150.094 1.00 23.19  ? 355  ILE B C     1 
ATOM   9383  O  O     . ILE B 2 340  ? 134.636 146.628 149.076 1.00 23.19  ? 355  ILE B O     1 
ATOM   9384  C  CB    . ILE B 2 340  ? 135.721 146.530 151.897 1.00 23.19  ? 355  ILE B CB    1 
ATOM   9385  C  CG1   . ILE B 2 340  ? 136.214 145.898 153.193 1.00 23.19  ? 355  ILE B CG1   1 
ATOM   9386  C  CG2   . ILE B 2 340  ? 135.210 147.929 152.143 1.00 23.19  ? 355  ILE B CG2   1 
ATOM   9387  C  CD1   . ILE B 2 340  ? 137.268 146.710 153.874 1.00 23.19  ? 355  ILE B CD1   1 
ATOM   9388  N  N     . LYS B 2 341  ? 132.700 146.724 150.238 1.00 15.08  ? 356  LYS B N     1 
ATOM   9389  C  CA    . LYS B 2 341  ? 131.931 147.334 149.163 1.00 15.08  ? 356  LYS B CA    1 
ATOM   9390  C  C     . LYS B 2 341  ? 131.636 148.808 149.377 1.00 15.08  ? 356  LYS B C     1 
ATOM   9391  O  O     . LYS B 2 341  ? 131.564 149.555 148.401 1.00 15.08  ? 356  LYS B O     1 
ATOM   9392  C  CB    . LYS B 2 341  ? 130.616 146.574 148.974 1.00 15.08  ? 356  LYS B CB    1 
ATOM   9393  C  CG    . LYS B 2 341  ? 130.836 145.079 148.872 1.00 15.08  ? 356  LYS B CG    1 
ATOM   9394  C  CD    . LYS B 2 341  ? 129.545 144.311 148.777 1.00 15.08  ? 356  LYS B CD    1 
ATOM   9395  C  CE    . LYS B 2 341  ? 129.814 142.819 148.767 1.00 15.08  ? 356  LYS B CE    1 
ATOM   9396  N  NZ    . LYS B 2 341  ? 130.767 142.433 147.697 1.00 15.08  ? 356  LYS B NZ    1 
ATOM   9397  N  N     . VAL B 2 342  ? 131.465 149.248 150.621 1.00 15.79  ? 357  VAL B N     1 
ATOM   9398  C  CA    . VAL B 2 342  ? 131.221 150.648 150.940 1.00 15.79  ? 357  VAL B CA    1 
ATOM   9399  C  C     . VAL B 2 342  ? 132.253 151.086 151.968 1.00 15.79  ? 357  VAL B C     1 
ATOM   9400  O  O     . VAL B 2 342  ? 132.599 150.322 152.875 1.00 15.79  ? 357  VAL B O     1 
ATOM   9401  C  CB    . VAL B 2 342  ? 129.791 150.872 151.474 1.00 15.79  ? 357  VAL B CB    1 
ATOM   9402  C  CG1   . VAL B 2 342  ? 129.489 152.354 151.587 1.00 15.79  ? 357  VAL B CG1   1 
ATOM   9403  C  CG2   . VAL B 2 342  ? 128.776 150.193 150.578 1.00 15.79  ? 357  VAL B CG2   1 
ATOM   9404  N  N     . ALA B 2 343  ? 132.754 152.311 151.824 1.00 17.24  ? 358  ALA B N     1 
ATOM   9405  C  CA    . ALA B 2 343  ? 133.754 152.862 152.738 1.00 17.24  ? 358  ALA B CA    1 
ATOM   9406  C  C     . ALA B 2 343  ? 133.287 154.242 153.188 1.00 17.24  ? 358  ALA B C     1 
ATOM   9407  O  O     . ALA B 2 343  ? 133.616 155.251 152.560 1.00 17.24  ? 358  ALA B O     1 
ATOM   9408  C  CB    . ALA B 2 343  ? 135.119 152.921 152.080 1.00 17.24  ? 358  ALA B CB    1 
ATOM   9409  N  N     . LEU B 2 344  ? 132.529 154.281 154.280 1.00 17.84  ? 359  LEU B N     1 
ATOM   9410  C  CA    . LEU B 2 344  ? 132.005 155.537 154.788 1.00 17.84  ? 359  LEU B CA    1 
ATOM   9411  C  C     . LEU B 2 344  ? 133.127 156.422 155.316 1.00 17.84  ? 359  LEU B C     1 
ATOM   9412  O  O     . LEU B 2 344  ? 134.216 155.961 155.665 1.00 17.84  ? 359  LEU B O     1 
ATOM   9413  C  CB    . LEU B 2 344  ? 130.983 155.287 155.892 1.00 17.84  ? 359  LEU B CB    1 
ATOM   9414  C  CG    . LEU B 2 344  ? 129.776 154.438 155.507 1.00 17.84  ? 359  LEU B CG    1 
ATOM   9415  C  CD1   . LEU B 2 344  ? 128.758 154.439 156.625 1.00 17.84  ? 359  LEU B CD1   1 
ATOM   9416  C  CD2   . LEU B 2 344  ? 129.159 154.952 154.226 1.00 17.84  ? 359  LEU B CD2   1 
ATOM   9417  N  N     . ASP B 2 345  ? 132.844 157.719 155.368 1.00 23.77  ? 360  ASP B N     1 
ATOM   9418  C  CA    . ASP B 2 345  ? 133.800 158.692 155.868 1.00 23.77  ? 360  ASP B CA    1 
ATOM   9419  C  C     . ASP B 2 345  ? 133.040 159.954 156.242 1.00 23.77  ? 360  ASP B C     1 
ATOM   9420  O  O     . ASP B 2 345  ? 131.884 160.142 155.855 1.00 23.77  ? 360  ASP B O     1 
ATOM   9421  C  CB    . ASP B 2 345  ? 134.890 158.995 154.836 1.00 23.77  ? 360  ASP B CB    1 
ATOM   9422  C  CG    . ASP B 2 345  ? 136.054 159.770 155.425 1.00 23.77  ? 360  ASP B CG    1 
ATOM   9423  O  OD1   . ASP B 2 345  ? 136.210 159.762 156.664 1.00 23.77  ? 360  ASP B OD1   1 
ATOM   9424  O  OD2   . ASP B 2 345  ? 136.805 160.399 154.651 1.00 23.77  ? 360  ASP B OD2   1 
ATOM   9425  N  N     . VAL B 2 346  ? 133.707 160.819 156.996 1.00 25.99  ? 361  VAL B N     1 
ATOM   9426  C  CA    . VAL B 2 346  ? 133.130 162.069 157.468 1.00 25.99  ? 361  VAL B CA    1 
ATOM   9427  C  C     . VAL B 2 346  ? 134.059 163.203 157.062 1.00 25.99  ? 361  VAL B C     1 
ATOM   9428  O  O     . VAL B 2 346  ? 135.276 163.115 157.258 1.00 25.99  ? 361  VAL B O     1 
ATOM   9429  C  CB    . VAL B 2 346  ? 132.909 162.045 158.991 1.00 25.99  ? 361  VAL B CB    1 
ATOM   9430  C  CG1   . VAL B 2 346  ? 132.642 163.441 159.509 1.00 25.99  ? 361  VAL B CG1   1 
ATOM   9431  C  CG2   . VAL B 2 346  ? 131.755 161.117 159.336 1.00 25.99  ? 361  VAL B CG2   1 
ATOM   9432  N  N     . GLY B 2 347  ? 133.486 164.258 156.492 1.00 30.55  ? 362  GLY B N     1 
ATOM   9433  C  CA    . GLY B 2 347  ? 134.273 165.348 155.952 1.00 30.55  ? 362  GLY B CA    1 
ATOM   9434  C  C     . GLY B 2 347  ? 134.971 166.213 156.981 1.00 30.55  ? 362  GLY B C     1 
ATOM   9435  O  O     . GLY B 2 347  ? 136.203 166.223 157.054 1.00 30.55  ? 362  GLY B O     1 
ATOM   9436  N  N     . LYS B 2 348  ? 134.200 166.941 157.781 1.00 45.50  ? 363  LYS B N     1 
ATOM   9437  C  CA    . LYS B 2 348  ? 134.765 167.934 158.688 1.00 45.50  ? 363  LYS B CA    1 
ATOM   9438  C  C     . LYS B 2 348  ? 133.768 168.179 159.820 1.00 45.50  ? 363  LYS B C     1 
ATOM   9439  O  O     . LYS B 2 348  ? 132.845 167.384 160.027 1.00 45.50  ? 363  LYS B O     1 
ATOM   9440  C  CB    . LYS B 2 348  ? 135.122 169.214 157.914 1.00 45.50  ? 363  LYS B CB    1 
ATOM   9441  C  CG    . LYS B 2 348  ? 134.008 169.717 157.016 1.00 45.50  ? 363  LYS B CG    1 
ATOM   9442  C  CD    . LYS B 2 348  ? 134.460 170.914 156.200 1.00 45.50  ? 363  LYS B CD    1 
ATOM   9443  C  CE    . LYS B 2 348  ? 133.391 171.338 155.208 1.00 45.50  ? 363  LYS B CE    1 
ATOM   9444  N  NZ    . LYS B 2 348  ? 133.823 172.508 154.396 1.00 45.50  ? 363  LYS B NZ    1 
ATOM   9445  N  N     . GLY B 2 349  ? 133.966 169.265 160.565 1.00 50.91  ? 364  GLY B N     1 
ATOM   9446  C  CA    . GLY B 2 349  ? 133.091 169.609 161.660 1.00 50.91  ? 364  GLY B CA    1 
ATOM   9447  C  C     . GLY B 2 349  ? 131.711 170.023 161.188 1.00 50.91  ? 364  GLY B C     1 
ATOM   9448  O  O     . GLY B 2 349  ? 131.531 170.473 160.053 1.00 50.91  ? 364  GLY B O     1 
ATOM   9449  N  N     . PRO B 2 350  ? 130.700 169.877 162.056 1.00 49.96  ? 365  PRO B N     1 
ATOM   9450  C  CA    . PRO B 2 350  ? 130.751 169.361 163.433 1.00 49.96  ? 365  PRO B CA    1 
ATOM   9451  C  C     . PRO B 2 350  ? 130.909 167.847 163.482 1.00 49.96  ? 365  PRO B C     1 
ATOM   9452  O  O     . PRO B 2 350  ? 130.321 167.121 162.685 1.00 49.96  ? 365  PRO B O     1 
ATOM   9453  C  CB    . PRO B 2 350  ? 129.406 169.813 164.012 1.00 49.96  ? 365  PRO B CB    1 
ATOM   9454  C  CG    . PRO B 2 350  ? 128.488 169.800 162.830 1.00 49.96  ? 365  PRO B CG    1 
ATOM   9455  C  CD    . PRO B 2 350  ? 129.334 170.284 161.680 1.00 49.96  ? 365  PRO B CD    1 
ATOM   9456  N  N     . THR B 2 351  ? 131.705 167.348 164.427 1.00 52.84  ? 366  THR B N     1 
ATOM   9457  C  CA    . THR B 2 351  ? 132.012 165.923 164.455 1.00 52.84  ? 366  THR B CA    1 
ATOM   9458  C  C     . THR B 2 351  ? 130.826 165.101 164.941 1.00 52.84  ? 366  THR B C     1 
ATOM   9459  O  O     . THR B 2 351  ? 130.535 164.038 164.383 1.00 52.84  ? 366  THR B O     1 
ATOM   9460  C  CB    . THR B 2 351  ? 133.233 165.669 165.336 1.00 52.84  ? 366  THR B CB    1 
ATOM   9461  O  OG1   . THR B 2 351  ? 132.967 166.130 166.666 1.00 52.84  ? 366  THR B OG1   1 
ATOM   9462  C  CG2   . THR B 2 351  ? 134.445 166.402 164.786 1.00 52.84  ? 366  THR B CG2   1 
ATOM   9463  N  N     . VAL B 2 352  ? 130.131 165.572 165.978 1.00 51.93  ? 367  VAL B N     1 
ATOM   9464  C  CA    . VAL B 2 352  ? 129.115 164.748 166.628 1.00 51.93  ? 367  VAL B CA    1 
ATOM   9465  C  C     . VAL B 2 352  ? 127.947 164.484 165.687 1.00 51.93  ? 367  VAL B C     1 
ATOM   9466  O  O     . VAL B 2 352  ? 127.513 163.338 165.519 1.00 51.93  ? 367  VAL B O     1 
ATOM   9467  C  CB    . VAL B 2 352  ? 128.643 165.412 167.934 1.00 51.93  ? 367  VAL B CB    1 
ATOM   9468  C  CG1   . VAL B 2 352  ? 127.651 164.511 168.651 1.00 51.93  ? 367  VAL B CG1   1 
ATOM   9469  C  CG2   . VAL B 2 352  ? 129.831 165.731 168.827 1.00 51.93  ? 367  VAL B CG2   1 
ATOM   9470  N  N     . GLU B 2 353  ? 127.422 165.537 165.056 1.00 49.43  ? 368  GLU B N     1 
ATOM   9471  C  CA    . GLU B 2 353  ? 126.259 165.375 164.189 1.00 49.43  ? 368  GLU B CA    1 
ATOM   9472  C  C     . GLU B 2 353  ? 126.596 164.556 162.951 1.00 49.43  ? 368  GLU B C     1 
ATOM   9473  O  O     . GLU B 2 353  ? 125.831 163.665 162.560 1.00 49.43  ? 368  GLU B O     1 
ATOM   9474  C  CB    . GLU B 2 353  ? 125.708 166.743 163.792 1.00 49.43  ? 368  GLU B CB    1 
ATOM   9475  C  CG    . GLU B 2 353  ? 125.111 167.524 164.946 1.00 49.43  ? 368  GLU B CG    1 
ATOM   9476  C  CD    . GLU B 2 353  ? 123.855 166.878 165.498 1.00 49.43  ? 368  GLU B CD    1 
ATOM   9477  O  OE1   . GLU B 2 353  ? 123.173 166.153 164.743 1.00 49.43  ? 368  GLU B OE1   1 
ATOM   9478  O  OE2   . GLU B 2 353  ? 123.550 167.096 166.689 1.00 49.43  ? 368  GLU B OE2   1 
ATOM   9479  N  N     . LEU B 2 354  ? 127.733 164.849 162.317 1.00 40.61  ? 369  LEU B N     1 
ATOM   9480  C  CA    . LEU B 2 354  ? 128.134 164.090 161.140 1.00 40.61  ? 369  LEU B CA    1 
ATOM   9481  C  C     . LEU B 2 354  ? 128.366 162.628 161.481 1.00 40.61  ? 369  LEU B C     1 
ATOM   9482  O  O     . LEU B 2 354  ? 127.993 161.739 160.710 1.00 40.61  ? 369  LEU B O     1 
ATOM   9483  C  CB    . LEU B 2 354  ? 129.390 164.696 160.518 1.00 40.61  ? 369  LEU B CB    1 
ATOM   9484  C  CG    . LEU B 2 354  ? 129.166 165.982 159.730 1.00 40.61  ? 369  LEU B CG    1 
ATOM   9485  C  CD1   . LEU B 2 354  ? 130.314 166.218 158.781 1.00 40.61  ? 369  LEU B CD1   1 
ATOM   9486  C  CD2   . LEU B 2 354  ? 127.859 165.905 158.970 1.00 40.61  ? 369  LEU B CD2   1 
ATOM   9487  N  N     . ARG B 2 355  ? 128.984 162.357 162.630 1.00 42.30  ? 370  ARG B N     1 
ATOM   9488  C  CA    . ARG B 2 355  ? 129.230 160.974 163.017 1.00 42.30  ? 370  ARG B CA    1 
ATOM   9489  C  C     . ARG B 2 355  ? 127.934 160.254 163.356 1.00 42.30  ? 370  ARG B C     1 
ATOM   9490  O  O     . ARG B 2 355  ? 127.790 159.063 163.066 1.00 42.30  ? 370  ARG B O     1 
ATOM   9491  C  CB    . ARG B 2 355  ? 130.211 160.923 164.186 1.00 42.30  ? 370  ARG B CB    1 
ATOM   9492  C  CG    . ARG B 2 355  ? 131.658 160.999 163.743 1.00 42.30  ? 370  ARG B CG    1 
ATOM   9493  C  CD    . ARG B 2 355  ? 132.615 160.812 164.900 1.00 42.30  ? 370  ARG B CD    1 
ATOM   9494  N  NE    . ARG B 2 355  ? 133.966 160.535 164.428 1.00 42.30  ? 370  ARG B NE    1 
ATOM   9495  C  CZ    . ARG B 2 355  ? 134.818 161.460 164.007 1.00 42.30  ? 370  ARG B CZ    1 
ATOM   9496  N  NH1   . ARG B 2 355  ? 134.489 162.741 163.980 1.00 42.30  ? 370  ARG B NH1   1 
ATOM   9497  N  NH2   . ARG B 2 355  ? 136.028 161.090 163.599 1.00 42.30  ? 370  ARG B NH2   1 
ATOM   9498  N  N     . GLN B 2 356  ? 126.971 160.957 163.955 1.00 43.47  ? 371  GLN B N     1 
ATOM   9499  C  CA    . GLN B 2 356  ? 125.670 160.345 164.196 1.00 43.47  ? 371  GLN B CA    1 
ATOM   9500  C  C     . GLN B 2 356  ? 124.972 160.008 162.883 1.00 43.47  ? 371  GLN B C     1 
ATOM   9501  O  O     . GLN B 2 356  ? 124.393 158.924 162.736 1.00 43.47  ? 371  GLN B O     1 
ATOM   9502  C  CB    . GLN B 2 356  ? 124.806 161.272 165.047 1.00 43.47  ? 371  GLN B CB    1 
ATOM   9503  C  CG    . GLN B 2 356  ? 123.446 160.699 165.386 1.00 43.47  ? 371  GLN B CG    1 
ATOM   9504  C  CD    . GLN B 2 356  ? 122.711 161.521 166.423 1.00 43.47  ? 371  GLN B CD    1 
ATOM   9505  O  OE1   . GLN B 2 356  ? 121.653 162.086 166.148 1.00 43.47  ? 371  GLN B OE1   1 
ATOM   9506  N  NE2   . GLN B 2 356  ? 123.267 161.587 167.626 1.00 43.47  ? 371  GLN B NE2   1 
ATOM   9507  N  N     . VAL B 2 357  ? 125.030 160.923 161.912 1.00 38.95  ? 372  VAL B N     1 
ATOM   9508  C  CA    . VAL B 2 357  ? 124.429 160.666 160.605 1.00 38.95  ? 372  VAL B CA    1 
ATOM   9509  C  C     . VAL B 2 357  ? 125.112 159.488 159.926 1.00 38.95  ? 372  VAL B C     1 
ATOM   9510  O  O     . VAL B 2 357  ? 124.452 158.621 159.339 1.00 38.95  ? 372  VAL B O     1 
ATOM   9511  C  CB    . VAL B 2 357  ? 124.494 161.930 159.729 1.00 38.95  ? 372  VAL B CB    1 
ATOM   9512  C  CG1   . VAL B 2 357  ? 124.119 161.598 158.295 1.00 38.95  ? 372  VAL B CG1   1 
ATOM   9513  C  CG2   . VAL B 2 357  ? 123.577 163.000 160.283 1.00 38.95  ? 372  VAL B CG2   1 
ATOM   9514  N  N     . CYS B 2 358  ? 126.444 159.449 159.979 1.00 37.18  ? 373  CYS B N     1 
ATOM   9515  C  CA    . CYS B 2 358  ? 127.188 158.368 159.347 1.00 37.18  ? 373  CYS B CA    1 
ATOM   9516  C  C     . CYS B 2 358  ? 126.894 157.033 160.015 1.00 37.18  ? 373  CYS B C     1 
ATOM   9517  O  O     . CYS B 2 358  ? 126.799 156.006 159.338 1.00 37.18  ? 373  CYS B O     1 
ATOM   9518  C  CB    . CYS B 2 358  ? 128.683 158.676 159.382 1.00 37.18  ? 373  CYS B CB    1 
ATOM   9519  S  SG    . CYS B 2 358  ? 129.674 157.653 158.276 1.00 37.18  ? 373  CYS B SG    1 
ATOM   9520  N  N     . GLN B 2 359  ? 126.746 157.025 161.341 1.00 35.59  ? 374  GLN B N     1 
ATOM   9521  C  CA    . GLN B 2 359  ? 126.371 155.798 162.032 1.00 35.59  ? 374  GLN B CA    1 
ATOM   9522  C  C     . GLN B 2 359  ? 124.977 155.343 161.628 1.00 35.59  ? 374  GLN B C     1 
ATOM   9523  O  O     . GLN B 2 359  ? 124.741 154.144 161.437 1.00 35.59  ? 374  GLN B O     1 
ATOM   9524  C  CB    . GLN B 2 359  ? 126.452 155.995 163.544 1.00 35.59  ? 374  GLN B CB    1 
ATOM   9525  C  CG    . GLN B 2 359  ? 126.065 154.759 164.337 1.00 35.59  ? 374  GLN B CG    1 
ATOM   9526  C  CD    . GLN B 2 359  ? 126.153 154.973 165.832 1.00 35.59  ? 374  GLN B CD    1 
ATOM   9527  O  OE1   . GLN B 2 359  ? 126.704 155.970 166.298 1.00 35.59  ? 374  GLN B OE1   1 
ATOM   9528  N  NE2   . GLN B 2 359  ? 125.604 154.035 166.595 1.00 35.59  ? 374  GLN B NE2   1 
ATOM   9529  N  N     . GLY B 2 360  ? 124.037 156.281 161.498 1.00 33.98  ? 375  GLY B N     1 
ATOM   9530  C  CA    . GLY B 2 360  ? 122.715 155.912 161.018 1.00 33.98  ? 375  GLY B CA    1 
ATOM   9531  C  C     . GLY B 2 360  ? 122.754 155.329 159.619 1.00 33.98  ? 375  GLY B C     1 
ATOM   9532  O  O     . GLY B 2 360  ? 122.101 154.321 159.333 1.00 33.98  ? 375  GLY B O     1 
ATOM   9533  N  N     . LEU B 2 361  ? 123.540 155.945 158.735 1.00 28.63  ? 376  LEU B N     1 
ATOM   9534  C  CA    . LEU B 2 361  ? 123.690 155.431 157.378 1.00 28.63  ? 376  LEU B CA    1 
ATOM   9535  C  C     . LEU B 2 361  ? 124.301 154.036 157.385 1.00 28.63  ? 376  LEU B C     1 
ATOM   9536  O  O     . LEU B 2 361  ? 123.856 153.150 156.647 1.00 28.63  ? 376  LEU B O     1 
ATOM   9537  C  CB    . LEU B 2 361  ? 124.546 156.396 156.558 1.00 28.63  ? 376  LEU B CB    1 
ATOM   9538  C  CG    . LEU B 2 361  ? 124.824 156.073 155.091 1.00 28.63  ? 376  LEU B CG    1 
ATOM   9539  C  CD1   . LEU B 2 361  ? 123.525 155.927 154.323 1.00 28.63  ? 376  LEU B CD1   1 
ATOM   9540  C  CD2   . LEU B 2 361  ? 125.697 157.152 154.472 1.00 28.63  ? 376  LEU B CD2   1 
ATOM   9541  N  N     . LEU B 2 362  ? 125.322 153.827 158.218 1.00 26.69  ? 377  LEU B N     1 
ATOM   9542  C  CA    . LEU B 2 362  ? 125.953 152.518 158.329 1.00 26.69  ? 377  LEU B CA    1 
ATOM   9543  C  C     . LEU B 2 362  ? 124.964 151.468 158.812 1.00 26.69  ? 377  LEU B C     1 
ATOM   9544  O  O     . LEU B 2 362  ? 124.920 150.355 158.278 1.00 26.69  ? 377  LEU B O     1 
ATOM   9545  C  CB    . LEU B 2 362  ? 127.156 152.610 159.268 1.00 26.69  ? 377  LEU B CB    1 
ATOM   9546  C  CG    . LEU B 2 362  ? 127.805 151.340 159.810 1.00 26.69  ? 377  LEU B CG    1 
ATOM   9547  C  CD1   . LEU B 2 362  ? 128.174 150.398 158.692 1.00 26.69  ? 377  LEU B CD1   1 
ATOM   9548  C  CD2   . LEU B 2 362  ? 129.036 151.697 160.617 1.00 26.69  ? 377  LEU B CD2   1 
ATOM   9549  N  N     . ASN B 2 363  ? 124.154 151.805 159.815 1.00 30.28  ? 378  ASN B N     1 
ATOM   9550  C  CA    . ASN B 2 363  ? 123.129 150.873 160.269 1.00 30.28  ? 378  ASN B CA    1 
ATOM   9551  C  C     . ASN B 2 363  ? 122.130 150.579 159.158 1.00 30.28  ? 378  ASN B C     1 
ATOM   9552  O  O     . ASN B 2 363  ? 121.636 149.451 159.039 1.00 30.28  ? 378  ASN B O     1 
ATOM   9553  C  CB    . ASN B 2 363  ? 122.416 151.427 161.501 1.00 30.28  ? 378  ASN B CB    1 
ATOM   9554  C  CG    . ASN B 2 363  ? 123.347 151.601 162.680 1.00 30.28  ? 378  ASN B CG    1 
ATOM   9555  O  OD1   . ASN B 2 363  ? 123.348 152.641 163.337 1.00 30.28  ? 378  ASN B OD1   1 
ATOM   9556  N  ND2   . ASN B 2 363  ? 124.151 150.582 162.954 1.00 30.28  ? 378  ASN B ND2   1 
ATOM   9557  N  N     . GLU B 2 364  ? 121.818 151.583 158.334 1.00 34.99  ? 379  GLU B N     1 
ATOM   9558  C  CA    . GLU B 2 364  ? 120.900 151.365 157.220 1.00 34.99  ? 379  GLU B CA    1 
ATOM   9559  C  C     . GLU B 2 364  ? 121.490 150.410 156.189 1.00 34.99  ? 379  GLU B C     1 
ATOM   9560  O  O     . GLU B 2 364  ? 120.788 149.531 155.673 1.00 34.99  ? 379  GLU B O     1 
ATOM   9561  C  CB    . GLU B 2 364  ? 120.539 152.697 156.565 1.00 34.99  ? 379  GLU B CB    1 
ATOM   9562  C  CG    . GLU B 2 364  ? 119.499 152.581 155.462 1.00 34.99  ? 379  GLU B CG    1 
ATOM   9563  C  CD    . GLU B 2 364  ? 118.143 152.136 155.981 1.00 34.99  ? 379  GLU B CD    1 
ATOM   9564  O  OE1   . GLU B 2 364  ? 117.835 152.414 157.160 1.00 34.99  ? 379  GLU B OE1   1 
ATOM   9565  O  OE2   . GLU B 2 364  ? 117.385 151.508 155.212 1.00 34.99  ? 379  GLU B OE2   1 
ATOM   9566  N  N     . LEU B 2 365  ? 122.774 150.579 155.863 1.00 25.17  ? 380  LEU B N     1 
ATOM   9567  C  CA    . LEU B 2 365  ? 123.413 149.726 154.865 1.00 25.17  ? 380  LEU B CA    1 
ATOM   9568  C  C     . LEU B 2 365  ? 123.475 148.274 155.324 1.00 25.17  ? 380  LEU B C     1 
ATOM   9569  O  O     . LEU B 2 365  ? 123.205 147.357 154.541 1.00 25.17  ? 380  LEU B O     1 
ATOM   9570  C  CB    . LEU B 2 365  ? 124.817 150.244 154.554 1.00 25.17  ? 380  LEU B CB    1 
ATOM   9571  C  CG    . LEU B 2 365  ? 124.917 151.621 153.899 1.00 25.17  ? 380  LEU B CG    1 
ATOM   9572  C  CD1   . LEU B 2 365  ? 126.368 152.028 153.705 1.00 25.17  ? 380  LEU B CD1   1 
ATOM   9573  C  CD2   . LEU B 2 365  ? 124.183 151.624 152.576 1.00 25.17  ? 380  LEU B CD2   1 
ATOM   9574  N  N     . LEU B 2 366  ? 123.828 148.048 156.592 1.00 24.45  ? 381  LEU B N     1 
ATOM   9575  C  CA    . LEU B 2 366  ? 124.060 146.691 157.077 1.00 24.45  ? 381  LEU B CA    1 
ATOM   9576  C  C     . LEU B 2 366  ? 122.788 145.855 157.082 1.00 24.45  ? 381  LEU B C     1 
ATOM   9577  O  O     . LEU B 2 366  ? 122.854 144.639 156.873 1.00 24.45  ? 381  LEU B O     1 
ATOM   9578  C  CB    . LEU B 2 366  ? 124.665 146.733 158.478 1.00 24.45  ? 381  LEU B CB    1 
ATOM   9579  C  CG    . LEU B 2 366  ? 126.045 147.374 158.604 1.00 24.45  ? 381  LEU B CG    1 
ATOM   9580  C  CD1   . LEU B 2 366  ? 126.506 147.372 160.048 1.00 24.45  ? 381  LEU B CD1   1 
ATOM   9581  C  CD2   . LEU B 2 366  ? 127.039 146.648 157.723 1.00 24.45  ? 381  LEU B CD2   1 
ATOM   9582  N  N     . GLU B 2 367  ? 121.631 146.474 157.327 1.00 33.67  ? 382  GLU B N     1 
ATOM   9583  C  CA    . GLU B 2 367  ? 120.393 145.705 157.428 1.00 33.67  ? 382  GLU B CA    1 
ATOM   9584  C  C     . GLU B 2 367  ? 120.063 145.004 156.116 1.00 33.67  ? 382  GLU B C     1 
ATOM   9585  O  O     . GLU B 2 367  ? 119.602 143.857 156.116 1.00 33.67  ? 382  GLU B O     1 
ATOM   9586  C  CB    . GLU B 2 367  ? 119.241 146.612 157.859 1.00 33.67  ? 382  GLU B CB    1 
ATOM   9587  C  CG    . GLU B 2 367  ? 119.381 147.150 159.271 1.00 33.67  ? 382  GLU B CG    1 
ATOM   9588  C  CD    . GLU B 2 367  ? 118.144 147.888 159.739 1.00 33.67  ? 382  GLU B CD    1 
ATOM   9589  O  OE1   . GLU B 2 367  ? 117.130 147.874 159.011 1.00 33.67  ? 382  GLU B OE1   1 
ATOM   9590  O  OE2   . GLU B 2 367  ? 118.186 148.483 160.837 1.00 33.67  ? 382  GLU B OE2   1 
ATOM   9591  N  N     . ASN B 2 368  ? 120.283 145.680 154.987 1.00 31.39  ? 383  ASN B N     1 
ATOM   9592  C  CA    . ASN B 2 368  ? 120.059 145.043 153.694 1.00 31.39  ? 383  ASN B CA    1 
ATOM   9593  C  C     . ASN B 2 368  ? 121.078 143.943 153.425 1.00 31.39  ? 383  ASN B C     1 
ATOM   9594  O  O     . ASN B 2 368  ? 120.733 142.918 152.826 1.00 31.39  ? 383  ASN B O     1 
ATOM   9595  C  CB    . ASN B 2 368  ? 120.088 146.089 152.581 1.00 31.39  ? 383  ASN B CB    1 
ATOM   9596  C  CG    . ASN B 2 368  ? 118.954 147.085 152.696 1.00 31.39  ? 383  ASN B CG    1 
ATOM   9597  O  OD1   . ASN B 2 368  ? 117.821 146.798 152.311 1.00 31.39  ? 383  ASN B OD1   1 
ATOM   9598  N  ND2   . ASN B 2 368  ? 119.251 148.262 153.229 1.00 31.39  ? 383  ASN B ND2   1 
ATOM   9599  N  N     . GLY B 2 369  ? 122.321 144.125 153.867 1.00 24.63  ? 384  GLY B N     1 
ATOM   9600  C  CA    . GLY B 2 369  ? 123.347 143.118 153.673 1.00 24.63  ? 384  GLY B CA    1 
ATOM   9601  C  C     . GLY B 2 369  ? 124.550 143.578 152.876 1.00 24.63  ? 384  GLY B C     1 
ATOM   9602  O  O     . GLY B 2 369  ? 125.201 142.770 152.208 1.00 24.63  ? 384  GLY B O     1 
ATOM   9603  N  N     . ILE B 2 370  ? 124.864 144.867 152.942 1.00 18.50  ? 385  ILE B N     1 
ATOM   9604  C  CA    . ILE B 2 370  ? 125.995 145.445 152.225 1.00 18.50  ? 385  ILE B CA    1 
ATOM   9605  C  C     . ILE B 2 370  ? 127.139 145.615 153.215 1.00 18.50  ? 385  ILE B C     1 
ATOM   9606  O  O     . ILE B 2 370  ? 126.978 146.266 154.254 1.00 18.50  ? 385  ILE B O     1 
ATOM   9607  C  CB    . ILE B 2 370  ? 125.623 146.781 151.568 1.00 18.50  ? 385  ILE B CB    1 
ATOM   9608  C  CG1   . ILE B 2 370  ? 124.372 146.617 150.704 1.00 18.50  ? 385  ILE B CG1   1 
ATOM   9609  C  CG2   . ILE B 2 370  ? 126.765 147.289 150.722 1.00 18.50  ? 385  ILE B CG2   1 
ATOM   9610  C  CD1   . ILE B 2 370  ? 123.933 147.892 150.026 1.00 18.50  ? 385  ILE B CD1   1 
ATOM   9611  N  N     . SER B 2 371  ? 128.290 145.030 152.897 1.00 15.51  ? 386  SER B N     1 
ATOM   9612  C  CA    . SER B 2 371  ? 129.428 145.025 153.809 1.00 15.51  ? 386  SER B CA    1 
ATOM   9613  C  C     . SER B 2 371  ? 130.128 146.377 153.768 1.00 15.51  ? 386  SER B C     1 
ATOM   9614  O  O     . SER B 2 371  ? 130.652 146.781 152.726 1.00 15.51  ? 386  SER B O     1 
ATOM   9615  C  CB    . SER B 2 371  ? 130.397 143.906 153.444 1.00 15.51  ? 386  SER B CB    1 
ATOM   9616  O  OG    . SER B 2 371  ? 130.949 144.119 152.159 1.00 15.51  ? 386  SER B OG    1 
ATOM   9617  N  N     . VAL B 2 372  ? 130.141 147.068 154.899 1.00 16.41  ? 387  VAL B N     1 
ATOM   9618  C  CA    . VAL B 2 372  ? 130.673 148.419 154.991 1.00 16.41  ? 387  VAL B CA    1 
ATOM   9619  C  C     . VAL B 2 372  ? 131.989 148.390 155.753 1.00 16.41  ? 387  VAL B C     1 
ATOM   9620  O  O     . VAL B 2 372  ? 132.228 147.516 156.592 1.00 16.41  ? 387  VAL B O     1 
ATOM   9621  C  CB    . VAL B 2 372  ? 129.660 149.359 155.676 1.00 16.41  ? 387  VAL B CB    1 
ATOM   9622  C  CG1   . VAL B 2 372  ? 130.059 150.811 155.504 1.00 16.41  ? 387  VAL B CG1   1 
ATOM   9623  C  CG2   . VAL B 2 372  ? 128.264 149.115 155.134 1.00 16.41  ? 387  VAL B CG2   1 
ATOM   9624  N  N     . TRP B 2 373  ? 132.845 149.359 155.453 1.00 15.93  ? 388  TRP B N     1 
ATOM   9625  C  CA    . TRP B 2 373  ? 134.079 149.578 156.195 1.00 15.93  ? 388  TRP B CA    1 
ATOM   9626  C  C     . TRP B 2 373  ? 133.980 150.902 156.934 1.00 15.93  ? 388  TRP B C     1 
ATOM   9627  O  O     . TRP B 2 373  ? 134.029 151.964 156.293 1.00 15.93  ? 388  TRP B O     1 
ATOM   9628  C  CB    . TRP B 2 373  ? 135.280 149.580 155.250 1.00 15.93  ? 388  TRP B CB    1 
ATOM   9629  C  CG    . TRP B 2 373  ? 136.534 150.134 155.840 1.00 15.93  ? 388  TRP B CG    1 
ATOM   9630  C  CD1   . TRP B 2 373  ? 137.006 151.405 155.712 1.00 15.93  ? 388  TRP B CD1   1 
ATOM   9631  C  CD2   . TRP B 2 373  ? 137.487 149.431 156.644 1.00 15.93  ? 388  TRP B CD2   1 
ATOM   9632  N  NE1   . TRP B 2 373  ? 138.192 151.541 156.389 1.00 15.93  ? 388  TRP B NE1   1 
ATOM   9633  C  CE2   . TRP B 2 373  ? 138.509 150.343 156.970 1.00 15.93  ? 388  TRP B CE2   1 
ATOM   9634  C  CE3   . TRP B 2 373  ? 137.574 148.121 157.122 1.00 15.93  ? 388  TRP B CE3   1 
ATOM   9635  C  CZ2   . TRP B 2 373  ? 139.603 149.988 157.751 1.00 15.93  ? 388  TRP B CZ2   1 
ATOM   9636  C  CZ3   . TRP B 2 373  ? 138.659 147.770 157.895 1.00 15.93  ? 388  TRP B CZ3   1 
ATOM   9637  C  CH2   . TRP B 2 373  ? 139.660 148.699 158.203 1.00 15.93  ? 388  TRP B CH2   1 
ATOM   9638  N  N     . PRO B 2 374  ? 133.831 150.909 158.254 1.00 20.77  ? 389  PRO B N     1 
ATOM   9639  C  CA    . PRO B 2 374  ? 133.714 152.188 158.964 1.00 20.77  ? 389  PRO B CA    1 
ATOM   9640  C  C     . PRO B 2 374  ? 135.029 152.947 158.976 1.00 20.77  ? 389  PRO B C     1 
ATOM   9641  O  O     . PRO B 2 374  ? 135.951 152.592 159.714 1.00 20.77  ? 389  PRO B O     1 
ATOM   9642  C  CB    . PRO B 2 374  ? 133.299 151.768 160.380 1.00 20.77  ? 389  PRO B CB    1 
ATOM   9643  C  CG    . PRO B 2 374  ? 132.809 150.356 160.251 1.00 20.77  ? 389  PRO B CG    1 
ATOM   9644  C  CD    . PRO B 2 374  ? 133.605 149.759 159.143 1.00 20.77  ? 389  PRO B CD    1 
ATOM   9645  N  N     . GLY B 2 375  ? 135.121 153.997 158.169 1.00 27.56  ? 390  GLY B N     1 
ATOM   9646  C  CA    . GLY B 2 375  ? 136.325 154.800 158.121 1.00 27.56  ? 390  GLY B CA    1 
ATOM   9647  C  C     . GLY B 2 375  ? 136.172 156.103 158.871 1.00 27.56  ? 390  GLY B C     1 
ATOM   9648  O  O     . GLY B 2 375  ? 137.129 156.867 159.018 1.00 27.56  ? 390  GLY B O     1 
ATOM   9649  N  N     . TYR B 2 376  ? 134.956 156.373 159.341 1.00 33.06  ? 391  TYR B N     1 
ATOM   9650  C  CA    . TYR B 2 376  ? 134.721 157.575 160.128 1.00 33.06  ? 391  TYR B CA    1 
ATOM   9651  C  C     . TYR B 2 376  ? 135.248 157.416 161.547 1.00 33.06  ? 391  TYR B C     1 
ATOM   9652  O  O     . TYR B 2 376  ? 135.773 158.370 162.129 1.00 33.06  ? 391  TYR B O     1 
ATOM   9653  C  CB    . TYR B 2 376  ? 133.229 157.907 160.142 1.00 33.06  ? 391  TYR B CB    1 
ATOM   9654  C  CG    . TYR B 2 376  ? 132.371 156.850 160.793 1.00 33.06  ? 391  TYR B CG    1 
ATOM   9655  C  CD1   . TYR B 2 376  ? 131.943 155.739 160.084 1.00 33.06  ? 391  TYR B CD1   1 
ATOM   9656  C  CD2   . TYR B 2 376  ? 131.987 156.965 162.118 1.00 33.06  ? 391  TYR B CD2   1 
ATOM   9657  C  CE1   . TYR B 2 376  ? 131.160 154.772 160.677 1.00 33.06  ? 391  TYR B CE1   1 
ATOM   9658  C  CE2   . TYR B 2 376  ? 131.205 156.003 162.719 1.00 33.06  ? 391  TYR B CE2   1 
ATOM   9659  C  CZ    . TYR B 2 376  ? 130.795 154.910 161.995 1.00 33.06  ? 391  TYR B CZ    1 
ATOM   9660  O  OH    . TYR B 2 376  ? 130.014 153.953 162.598 1.00 33.06  ? 391  TYR B OH    1 
ATOM   9661  N  N     . SER B 2 377  ? 135.121 156.215 162.112 1.00 36.12  ? 392  SER B N     1 
ATOM   9662  C  CA    . SER B 2 377  ? 135.591 155.937 163.461 1.00 36.12  ? 392  SER B CA    1 
ATOM   9663  C  C     . SER B 2 377  ? 137.101 155.778 163.543 1.00 36.12  ? 392  SER B C     1 
ATOM   9664  O  O     . SER B 2 377  ? 137.637 155.683 164.651 1.00 36.12  ? 392  SER B O     1 
ATOM   9665  C  CB    . SER B 2 377  ? 134.917 154.674 164.000 1.00 36.12  ? 392  SER B CB    1 
ATOM   9666  O  OG    . SER B 2 377  ? 135.202 153.557 163.178 1.00 36.12  ? 392  SER B OG    1 
ATOM   9667  N  N     . GLU B 2 378  ? 137.794 155.740 162.410 1.00 51.94  ? 393  GLU B N     1 
ATOM   9668  C  CA    . GLU B 2 378  ? 139.244 155.611 162.420 1.00 51.94  ? 393  GLU B CA    1 
ATOM   9669  C  C     . GLU B 2 378  ? 139.869 156.887 162.967 1.00 51.94  ? 393  GLU B C     1 
ATOM   9670  O  O     . GLU B 2 378  ? 139.679 157.971 162.406 1.00 51.94  ? 393  GLU B O     1 
ATOM   9671  C  CB    . GLU B 2 378  ? 139.755 155.321 161.012 1.00 51.94  ? 393  GLU B CB    1 
ATOM   9672  C  CG    . GLU B 2 378  ? 141.262 155.184 160.911 1.00 51.94  ? 393  GLU B CG    1 
ATOM   9673  C  CD    . GLU B 2 378  ? 141.723 154.954 159.487 1.00 51.94  ? 393  GLU B CD    1 
ATOM   9674  O  OE1   . GLU B 2 378  ? 140.898 155.117 158.563 1.00 51.94  ? 393  GLU B OE1   1 
ATOM   9675  O  OE2   . GLU B 2 378  ? 142.907 154.607 159.292 1.00 51.94  ? 393  GLU B OE2   1 
ATOM   9676  N  N     . THR B 2 379  ? 140.612 156.758 164.066 1.00 63.72  ? 394  THR B N     1 
ATOM   9677  C  CA    . THR B 2 379  ? 141.252 157.911 164.684 1.00 63.72  ? 394  THR B CA    1 
ATOM   9678  C  C     . THR B 2 379  ? 142.464 158.397 163.904 1.00 63.72  ? 394  THR B C     1 
ATOM   9679  O  O     . THR B 2 379  ? 142.881 159.546 164.084 1.00 63.72  ? 394  THR B O     1 
ATOM   9680  C  CB    . THR B 2 379  ? 141.669 157.576 166.117 1.00 63.72  ? 394  THR B CB    1 
ATOM   9681  O  OG1   . THR B 2 379  ? 142.608 156.495 166.101 1.00 63.72  ? 394  THR B OG1   1 
ATOM   9682  C  CG2   . THR B 2 379  ? 140.455 157.171 166.938 1.00 63.72  ? 394  THR B CG2   1 
ATOM   9683  N  N     . VAL B 2 380  ? 143.035 157.556 163.046 1.00 66.36  ? 395  VAL B N     1 
ATOM   9684  C  CA    . VAL B 2 380  ? 144.178 157.947 162.228 1.00 66.36  ? 395  VAL B CA    1 
ATOM   9685  C  C     . VAL B 2 380  ? 143.653 158.764 161.053 1.00 66.36  ? 395  VAL B C     1 
ATOM   9686  O  O     . VAL B 2 380  ? 142.969 158.237 160.173 1.00 66.36  ? 395  VAL B O     1 
ATOM   9687  C  CB    . VAL B 2 380  ? 144.970 156.726 161.748 1.00 66.36  ? 395  VAL B CB    1 
ATOM   9688  C  CG1   . VAL B 2 380  ? 146.130 157.161 160.869 1.00 66.36  ? 395  VAL B CG1   1 
ATOM   9689  C  CG2   . VAL B 2 380  ? 145.468 155.920 162.938 1.00 66.36  ? 395  VAL B CG2   1 
ATOM   9690  N  N     . HIS B 2 381  ? 143.969 160.056 161.039 1.00 70.71  ? 396  HIS B N     1 
ATOM   9691  C  CA    . HIS B 2 381  ? 143.498 160.953 159.996 1.00 70.71  ? 396  HIS B CA    1 
ATOM   9692  C  C     . HIS B 2 381  ? 144.522 161.044 158.873 1.00 70.71  ? 396  HIS B C     1 
ATOM   9693  O  O     . HIS B 2 381  ? 145.725 161.169 159.119 1.00 70.71  ? 396  HIS B O     1 
ATOM   9694  C  CB    . HIS B 2 381  ? 143.216 162.342 160.569 1.00 70.71  ? 396  HIS B CB    1 
ATOM   9695  C  CG    . HIS B 2 381  ? 142.196 162.346 161.664 1.00 70.71  ? 396  HIS B CG    1 
ATOM   9696  N  ND1   . HIS B 2 381  ? 140.843 162.243 161.420 1.00 70.71  ? 396  HIS B ND1   1 
ATOM   9697  C  CD2   . HIS B 2 381  ? 142.330 162.438 163.008 1.00 70.71  ? 396  HIS B CD2   1 
ATOM   9698  C  CE1   . HIS B 2 381  ? 140.188 162.272 162.567 1.00 70.71  ? 396  HIS B CE1   1 
ATOM   9699  N  NE2   . HIS B 2 381  ? 141.067 162.390 163.546 1.00 70.71  ? 396  HIS B NE2   1 
ATOM   9700  N  N     . SER B 2 382  ? 144.033 160.979 157.637 1.00 59.33  ? 397  SER B N     1 
ATOM   9701  C  CA    . SER B 2 382  ? 144.887 160.995 156.460 1.00 59.33  ? 397  SER B CA    1 
ATOM   9702  C  C     . SER B 2 382  ? 144.204 161.785 155.354 1.00 59.33  ? 397  SER B C     1 
ATOM   9703  O  O     . SER B 2 382  ? 142.997 162.035 155.394 1.00 59.33  ? 397  SER B O     1 
ATOM   9704  C  CB    . SER B 2 382  ? 145.208 159.574 155.977 1.00 59.33  ? 397  SER B CB    1 
ATOM   9705  O  OG    . SER B 2 382  ? 144.021 158.865 155.668 1.00 59.33  ? 397  SER B OG    1 
ATOM   9706  N  N     . SER B 2 383  ? 144.997 162.182 154.363 1.00 54.26  ? 398  SER B N     1 
ATOM   9707  C  CA    . SER B 2 383  ? 144.469 162.927 153.233 1.00 54.26  ? 398  SER B CA    1 
ATOM   9708  C  C     . SER B 2 383  ? 143.523 162.057 152.409 1.00 54.26  ? 398  SER B C     1 
ATOM   9709  O  O     . SER B 2 383  ? 143.528 160.826 152.497 1.00 54.26  ? 398  SER B O     1 
ATOM   9710  C  CB    . SER B 2 383  ? 145.606 163.445 152.352 1.00 54.26  ? 398  SER B CB    1 
ATOM   9711  O  OG    . SER B 2 383  ? 146.368 162.375 151.822 1.00 54.26  ? 398  SER B OG    1 
ATOM   9712  N  N     . LEU B 2 384  ? 142.695 162.723 151.602 1.00 48.55  ? 399  LEU B N     1 
ATOM   9713  C  CA    . LEU B 2 384  ? 141.730 162.008 150.773 1.00 48.55  ? 399  LEU B CA    1 
ATOM   9714  C  C     . LEU B 2 384  ? 142.424 161.117 149.752 1.00 48.55  ? 399  LEU B C     1 
ATOM   9715  O  O     . LEU B 2 384  ? 141.936 160.025 149.441 1.00 48.55  ? 399  LEU B O     1 
ATOM   9716  C  CB    . LEU B 2 384  ? 140.803 163.000 150.072 1.00 48.55  ? 399  LEU B CB    1 
ATOM   9717  C  CG    . LEU B 2 384  ? 139.772 163.704 150.952 1.00 48.55  ? 399  LEU B CG    1 
ATOM   9718  C  CD1   . LEU B 2 384  ? 139.016 164.750 150.151 1.00 48.55  ? 399  LEU B CD1   1 
ATOM   9719  C  CD2   . LEU B 2 384  ? 138.812 162.689 151.551 1.00 48.55  ? 399  LEU B CD2   1 
ATOM   9720  N  N     . GLU B 2 385  ? 143.552 161.573 149.205 1.00 47.41  ? 400  GLU B N     1 
ATOM   9721  C  CA    . GLU B 2 385  ? 144.259 160.788 148.197 1.00 47.41  ? 400  GLU B CA    1 
ATOM   9722  C  C     . GLU B 2 385  ? 144.727 159.453 148.762 1.00 47.41  ? 400  GLU B C     1 
ATOM   9723  O  O     . GLU B 2 385  ? 144.531 158.399 148.143 1.00 47.41  ? 400  GLU B O     1 
ATOM   9724  C  CB    . GLU B 2 385  ? 145.442 161.587 147.653 1.00 47.41  ? 400  GLU B CB    1 
ATOM   9725  C  CG    . GLU B 2 385  ? 146.361 160.793 146.742 1.00 47.41  ? 400  GLU B CG    1 
ATOM   9726  C  CD    . GLU B 2 385  ? 147.545 161.607 146.262 1.00 47.41  ? 400  GLU B CD    1 
ATOM   9727  O  OE1   . GLU B 2 385  ? 147.527 162.843 146.437 1.00 47.41  ? 400  GLU B OE1   1 
ATOM   9728  O  OE2   . GLU B 2 385  ? 148.496 161.011 145.712 1.00 47.41  ? 400  GLU B OE2   1 
ATOM   9729  N  N     . GLN B 2 386  ? 145.349 159.477 149.943 1.00 41.69  ? 401  GLN B N     1 
ATOM   9730  C  CA    . GLN B 2 386  ? 145.820 158.240 150.557 1.00 41.69  ? 401  GLN B CA    1 
ATOM   9731  C  C     . GLN B 2 386  ? 144.657 157.338 150.947 1.00 41.69  ? 401  GLN B C     1 
ATOM   9732  O  O     . GLN B 2 386  ? 144.744 156.113 150.815 1.00 41.69  ? 401  GLN B O     1 
ATOM   9733  C  CB    . GLN B 2 386  ? 146.688 158.555 151.773 1.00 41.69  ? 401  GLN B CB    1 
ATOM   9734  C  CG    . GLN B 2 386  ? 147.912 159.393 151.454 1.00 41.69  ? 401  GLN B CG    1 
ATOM   9735  C  CD    . GLN B 2 386  ? 148.741 159.701 152.684 1.00 41.69  ? 401  GLN B CD    1 
ATOM   9736  O  OE1   . GLN B 2 386  ? 148.527 159.125 153.750 1.00 41.69  ? 401  GLN B OE1   1 
ATOM   9737  N  NE2   . GLN B 2 386  ? 149.692 160.616 152.542 1.00 41.69  ? 401  GLN B NE2   1 
ATOM   9738  N  N     . LEU B 2 387  ? 143.563 157.926 151.431 1.00 33.45  ? 402  LEU B N     1 
ATOM   9739  C  CA    . LEU B 2 387  ? 142.380 157.140 151.764 1.00 33.45  ? 402  LEU B CA    1 
ATOM   9740  C  C     . LEU B 2 387  ? 141.823 156.438 150.533 1.00 33.45  ? 402  LEU B C     1 
ATOM   9741  O  O     . LEU B 2 387  ? 141.469 155.252 150.583 1.00 33.45  ? 402  LEU B O     1 
ATOM   9742  C  CB    . LEU B 2 387  ? 141.325 158.053 152.387 1.00 33.45  ? 402  LEU B CB    1 
ATOM   9743  C  CG    . LEU B 2 387  ? 140.093 157.425 153.028 1.00 33.45  ? 402  LEU B CG    1 
ATOM   9744  C  CD1   . LEU B 2 387  ? 140.458 156.750 154.337 1.00 33.45  ? 402  LEU B CD1   1 
ATOM   9745  C  CD2   . LEU B 2 387  ? 139.021 158.477 153.241 1.00 33.45  ? 402  LEU B CD2   1 
ATOM   9746  N  N     . HIS B 2 388  ? 141.752 157.155 149.411 1.00 29.72  ? 403  HIS B N     1 
ATOM   9747  C  CA    . HIS B 2 388  ? 141.236 156.570 148.180 1.00 29.72  ? 403  HIS B CA    1 
ATOM   9748  C  C     . HIS B 2 388  ? 142.168 155.492 147.648 1.00 29.72  ? 403  HIS B C     1 
ATOM   9749  O  O     . HIS B 2 388  ? 141.707 154.463 147.145 1.00 29.72  ? 403  HIS B O     1 
ATOM   9750  C  CB    . HIS B 2 388  ? 141.016 157.664 147.136 1.00 29.72  ? 403  HIS B CB    1 
ATOM   9751  C  CG    . HIS B 2 388  ? 139.852 158.556 147.434 1.00 29.72  ? 403  HIS B CG    1 
ATOM   9752  N  ND1   . HIS B 2 388  ? 138.735 158.118 148.112 1.00 29.72  ? 403  HIS B ND1   1 
ATOM   9753  C  CD2   . HIS B 2 388  ? 139.633 159.861 147.151 1.00 29.72  ? 403  HIS B CD2   1 
ATOM   9754  C  CE1   . HIS B 2 388  ? 137.876 159.114 148.231 1.00 29.72  ? 403  HIS B CE1   1 
ATOM   9755  N  NE2   . HIS B 2 388  ? 138.397 160.183 147.656 1.00 29.72  ? 403  HIS B NE2   1 
ATOM   9756  N  N     . SER B 2 389  ? 143.482 155.707 147.745 1.00 26.03  ? 404  SER B N     1 
ATOM   9757  C  CA    . SER B 2 389  ? 144.430 154.674 147.336 1.00 26.03  ? 404  SER B CA    1 
ATOM   9758  C  C     . SER B 2 389  ? 144.291 153.425 148.199 1.00 26.03  ? 404  SER B C     1 
ATOM   9759  O  O     . SER B 2 389  ? 144.308 152.297 147.688 1.00 26.03  ? 404  SER B O     1 
ATOM   9760  C  CB    . SER B 2 389  ? 145.855 155.218 147.403 1.00 26.03  ? 404  SER B CB    1 
ATOM   9761  O  OG    . SER B 2 389  ? 146.793 154.229 147.021 1.00 26.03  ? 404  SER B OG    1 
ATOM   9762  N  N     . LYS B 2 390  ? 144.150 153.611 149.512 1.00 22.37  ? 405  LYS B N     1 
ATOM   9763  C  CA    . LYS B 2 390  ? 143.954 152.484 150.414 1.00 22.37  ? 405  LYS B CA    1 
ATOM   9764  C  C     . LYS B 2 390  ? 142.691 151.712 150.064 1.00 22.37  ? 405  LYS B C     1 
ATOM   9765  O  O     . LYS B 2 390  ? 142.684 150.476 150.084 1.00 22.37  ? 405  LYS B O     1 
ATOM   9766  C  CB    . LYS B 2 390  ? 143.899 152.982 151.855 1.00 22.37  ? 405  LYS B CB    1 
ATOM   9767  C  CG    . LYS B 2 390  ? 143.167 152.060 152.800 1.00 22.37  ? 405  LYS B CG    1 
ATOM   9768  C  CD    . LYS B 2 390  ? 143.197 152.591 154.217 1.00 22.37  ? 405  LYS B CD    1 
ATOM   9769  C  CE    . LYS B 2 390  ? 142.401 151.698 155.148 1.00 22.37  ? 405  LYS B CE    1 
ATOM   9770  N  NZ    . LYS B 2 390  ? 142.518 152.132 156.564 1.00 22.37  ? 405  LYS B NZ    1 
ATOM   9771  N  N     . TYR B 2 391  ? 141.608 152.422 149.749 1.00 20.51  ? 406  TYR B N     1 
ATOM   9772  C  CA    . TYR B 2 391  ? 140.377 151.739 149.371 1.00 20.51  ? 406  TYR B CA    1 
ATOM   9773  C  C     . TYR B 2 391  ? 140.501 151.053 148.017 1.00 20.51  ? 406  TYR B C     1 
ATOM   9774  O  O     . TYR B 2 391  ? 139.883 150.007 147.798 1.00 20.51  ? 406  TYR B O     1 
ATOM   9775  C  CB    . TYR B 2 391  ? 139.212 152.724 149.370 1.00 20.51  ? 406  TYR B CB    1 
ATOM   9776  C  CG    . TYR B 2 391  ? 138.830 153.181 150.754 1.00 20.51  ? 406  TYR B CG    1 
ATOM   9777  C  CD1   . TYR B 2 391  ? 138.972 152.338 151.843 1.00 20.51  ? 406  TYR B CD1   1 
ATOM   9778  C  CD2   . TYR B 2 391  ? 138.339 154.454 150.974 1.00 20.51  ? 406  TYR B CD2   1 
ATOM   9779  C  CE1   . TYR B 2 391  ? 138.629 152.748 153.111 1.00 20.51  ? 406  TYR B CE1   1 
ATOM   9780  C  CE2   . TYR B 2 391  ? 137.992 154.872 152.239 1.00 20.51  ? 406  TYR B CE2   1 
ATOM   9781  C  CZ    . TYR B 2 391  ? 138.141 154.016 153.304 1.00 20.51  ? 406  TYR B CZ    1 
ATOM   9782  O  OH    . TYR B 2 391  ? 137.797 154.431 154.569 1.00 20.51  ? 406  TYR B OH    1 
ATOM   9783  N  N     . ASP B 2 392  ? 141.276 151.629 147.095 1.00 21.92  ? 407  ASP B N     1 
ATOM   9784  C  CA    . ASP B 2 392  ? 141.536 150.962 145.824 1.00 21.92  ? 407  ASP B CA    1 
ATOM   9785  C  C     . ASP B 2 392  ? 142.246 149.634 146.046 1.00 21.92  ? 407  ASP B C     1 
ATOM   9786  O  O     . ASP B 2 392  ? 141.836 148.599 145.509 1.00 21.92  ? 407  ASP B O     1 
ATOM   9787  C  CB    . ASP B 2 392  ? 142.368 151.864 144.914 1.00 21.92  ? 407  ASP B CB    1 
ATOM   9788  C  CG    . ASP B 2 392  ? 141.603 153.075 144.435 1.00 21.92  ? 407  ASP B CG    1 
ATOM   9789  O  OD1   . ASP B 2 392  ? 140.426 153.224 144.820 1.00 21.92  ? 407  ASP B OD1   1 
ATOM   9790  O  OD2   . ASP B 2 392  ? 142.180 153.878 143.675 1.00 21.92  ? 407  ASP B OD2   1 
ATOM   9791  N  N     . GLU B 2 393  ? 143.315 149.647 146.846 1.00 19.54  ? 408  GLU B N     1 
ATOM   9792  C  CA    . GLU B 2 393  ? 144.083 148.428 147.080 1.00 19.54  ? 408  GLU B CA    1 
ATOM   9793  C  C     . GLU B 2 393  ? 143.241 147.362 147.768 1.00 19.54  ? 408  GLU B C     1 
ATOM   9794  O  O     . GLU B 2 393  ? 143.357 146.173 147.454 1.00 19.54  ? 408  GLU B O     1 
ATOM   9795  C  CB    . GLU B 2 393  ? 145.327 148.747 147.903 1.00 19.54  ? 408  GLU B CB    1 
ATOM   9796  C  CG    . GLU B 2 393  ? 146.259 149.736 147.233 1.00 19.54  ? 408  GLU B CG    1 
ATOM   9797  C  CD    . GLU B 2 393  ? 147.418 150.137 148.119 1.00 19.54  ? 408  GLU B CD    1 
ATOM   9798  O  OE1   . GLU B 2 393  ? 147.466 149.676 149.278 1.00 19.54  ? 408  GLU B OE1   1 
ATOM   9799  O  OE2   . GLU B 2 393  ? 148.280 150.912 147.658 1.00 19.54  ? 408  GLU B OE2   1 
ATOM   9800  N  N     . MET B 2 394  ? 142.392 147.763 148.711 1.00 15.73  ? 409  MET B N     1 
ATOM   9801  C  CA    . MET B 2 394  ? 141.506 146.832 149.395 1.00 15.73  ? 409  MET B CA    1 
ATOM   9802  C  C     . MET B 2 394  ? 140.300 146.435 148.558 1.00 15.73  ? 409  MET B C     1 
ATOM   9803  O  O     . MET B 2 394  ? 139.438 145.707 149.060 1.00 15.73  ? 409  MET B O     1 
ATOM   9804  C  CB    . MET B 2 394  ? 141.028 147.433 150.717 1.00 15.73  ? 409  MET B CB    1 
ATOM   9805  C  CG    . MET B 2 394  ? 142.153 147.777 151.666 1.00 15.73  ? 409  MET B CG    1 
ATOM   9806  S  SD    . MET B 2 394  ? 141.663 148.915 152.970 1.00 15.73  ? 409  MET B SD    1 
ATOM   9807  C  CE    . MET B 2 394  ? 140.600 147.877 153.959 1.00 15.73  ? 409  MET B CE    1 
ATOM   9808  N  N     . SER B 2 395  ? 140.215 146.901 147.311 1.00 21.72  ? 410  SER B N     1 
ATOM   9809  C  CA    . SER B 2 395  ? 139.110 146.579 146.411 1.00 21.72  ? 410  SER B CA    1 
ATOM   9810  C  C     . SER B 2 395  ? 137.771 147.020 147.004 1.00 21.72  ? 410  SER B C     1 
ATOM   9811  O  O     . SER B 2 395  ? 136.854 146.222 147.213 1.00 21.72  ? 410  SER B O     1 
ATOM   9812  C  CB    . SER B 2 395  ? 139.095 145.087 146.071 1.00 21.72  ? 410  SER B CB    1 
ATOM   9813  O  OG    . SER B 2 395  ? 137.934 144.755 145.334 1.00 21.72  ? 410  SER B OG    1 
ATOM   9814  N  N     . VAL B 2 396  ? 137.676 148.318 147.273 1.00 14.50  ? 411  VAL B N     1 
ATOM   9815  C  CA    . VAL B 2 396  ? 136.453 148.918 147.787 1.00 14.50  ? 411  VAL B CA    1 
ATOM   9816  C  C     . VAL B 2 396  ? 135.673 149.480 146.610 1.00 14.50  ? 411  VAL B C     1 
ATOM   9817  O  O     . VAL B 2 396  ? 136.145 150.390 145.921 1.00 14.50  ? 411  VAL B O     1 
ATOM   9818  C  CB    . VAL B 2 396  ? 136.758 150.012 148.819 1.00 14.50  ? 411  VAL B CB    1 
ATOM   9819  C  CG1   . VAL B 2 396  ? 135.469 150.617 149.335 1.00 14.50  ? 411  VAL B CG1   1 
ATOM   9820  C  CG2   . VAL B 2 396  ? 137.582 149.446 149.958 1.00 14.50  ? 411  VAL B CG2   1 
ATOM   9821  N  N     . LEU B 2 397  ? 134.474 148.941 146.385 1.00 27.52  ? 412  LEU B N     1 
ATOM   9822  C  CA    . LEU B 2 397  ? 133.679 149.330 145.225 1.00 27.52  ? 412  LEU B CA    1 
ATOM   9823  C  C     . LEU B 2 397  ? 133.301 150.805 145.277 1.00 27.52  ? 412  LEU B C     1 
ATOM   9824  O  O     . LEU B 2 397  ? 133.527 151.549 144.316 1.00 27.52  ? 412  LEU B O     1 
ATOM   9825  C  CB    . LEU B 2 397  ? 132.428 148.459 145.140 1.00 27.52  ? 412  LEU B CB    1 
ATOM   9826  C  CG    . LEU B 2 397  ? 132.646 146.966 144.917 1.00 27.52  ? 412  LEU B CG    1 
ATOM   9827  C  CD1   . LEU B 2 397  ? 131.345 146.209 145.042 1.00 27.52  ? 412  LEU B CD1   1 
ATOM   9828  C  CD2   . LEU B 2 397  ? 133.253 146.746 143.556 1.00 27.52  ? 412  LEU B CD2   1 
ATOM   9829  N  N     . PHE B 2 398  ? 132.727 151.248 146.397 1.00 38.40  ? 413  PHE B N     1 
ATOM   9830  C  CA    . PHE B 2 398  ? 132.177 152.591 146.522 1.00 38.40  ? 413  PHE B CA    1 
ATOM   9831  C  C     . PHE B 2 398  ? 132.698 153.271 147.777 1.00 38.40  ? 413  PHE B C     1 
ATOM   9832  O  O     . PHE B 2 398  ? 132.810 152.644 148.833 1.00 38.40  ? 413  PHE B O     1 
ATOM   9833  C  CB    . PHE B 2 398  ? 130.651 152.556 146.561 1.00 38.40  ? 413  PHE B CB    1 
ATOM   9834  C  CG    . PHE B 2 398  ? 130.032 151.993 145.322 1.00 38.40  ? 413  PHE B CG    1 
ATOM   9835  C  CD1   . PHE B 2 398  ? 130.057 152.708 144.140 1.00 38.40  ? 413  PHE B CD1   1 
ATOM   9836  C  CD2   . PHE B 2 398  ? 129.425 150.752 145.339 1.00 38.40  ? 413  PHE B CD2   1 
ATOM   9837  C  CE1   . PHE B 2 398  ? 129.492 152.196 143.000 1.00 38.40  ? 413  PHE B CE1   1 
ATOM   9838  C  CE2   . PHE B 2 398  ? 128.857 150.236 144.202 1.00 38.40  ? 413  PHE B CE2   1 
ATOM   9839  C  CZ    . PHE B 2 398  ? 128.891 150.958 143.030 1.00 38.40  ? 413  PHE B CZ    1 
ATOM   9840  N  N     . SER B 2 399  ? 133.000 154.560 147.659 1.00 16.53  ? 414  SER B N     1 
ATOM   9841  C  CA    . SER B 2 399  ? 133.455 155.375 148.776 1.00 16.53  ? 414  SER B CA    1 
ATOM   9842  C  C     . SER B 2 399  ? 132.464 156.506 149.003 1.00 16.53  ? 414  SER B C     1 
ATOM   9843  O  O     . SER B 2 399  ? 132.165 157.268 148.077 1.00 16.53  ? 414  SER B O     1 
ATOM   9844  C  CB    . SER B 2 399  ? 134.852 155.936 148.514 1.00 16.53  ? 414  SER B CB    1 
ATOM   9845  O  OG    . SER B 2 399  ? 135.204 156.895 149.493 1.00 16.53  ? 414  SER B OG    1 
ATOM   9846  N  N     . VAL B 2 400  ? 131.963 156.616 150.230 1.00 20.48  ? 415  VAL B N     1 
ATOM   9847  C  CA    . VAL B 2 400  ? 130.940 157.589 150.595 1.00 20.48  ? 415  VAL B CA    1 
ATOM   9848  C  C     . VAL B 2 400  ? 131.559 158.612 151.534 1.00 20.48  ? 415  VAL B C     1 
ATOM   9849  O  O     . VAL B 2 400  ? 132.297 158.250 152.457 1.00 20.48  ? 415  VAL B O     1 
ATOM   9850  C  CB    . VAL B 2 400  ? 129.728 156.909 151.254 1.00 20.48  ? 415  VAL B CB    1 
ATOM   9851  C  CG1   . VAL B 2 400  ? 128.671 157.935 151.597 1.00 20.48  ? 415  VAL B CG1   1 
ATOM   9852  C  CG2   . VAL B 2 400  ? 129.165 155.833 150.350 1.00 20.48  ? 415  VAL B CG2   1 
ATOM   9853  N  N     . LEU B 2 401  ? 131.265 159.886 151.296 1.00 20.32  ? 416  LEU B N     1 
ATOM   9854  C  CA    . LEU B 2 401  ? 131.714 160.973 152.154 1.00 20.32  ? 416  LEU B CA    1 
ATOM   9855  C  C     . LEU B 2 401  ? 130.500 161.754 152.630 1.00 20.32  ? 416  LEU B C     1 
ATOM   9856  O  O     . LEU B 2 401  ? 129.692 162.212 151.816 1.00 20.32  ? 416  LEU B O     1 
ATOM   9857  C  CB    . LEU B 2 401  ? 132.686 161.896 151.420 1.00 20.32  ? 416  LEU B CB    1 
ATOM   9858  C  CG    . LEU B 2 401  ? 133.300 163.024 152.246 1.00 20.32  ? 416  LEU B CG    1 
ATOM   9859  C  CD1   . LEU B 2 401  ? 134.127 162.451 153.379 1.00 20.32  ? 416  LEU B CD1   1 
ATOM   9860  C  CD2   . LEU B 2 401  ? 134.145 163.934 151.374 1.00 20.32  ? 416  LEU B CD2   1 
ATOM   9861  N  N     . VAL B 2 402  ? 130.375 161.904 153.942 1.00 24.52  ? 417  VAL B N     1 
ATOM   9862  C  CA    . VAL B 2 402  ? 129.251 162.593 154.561 1.00 24.52  ? 417  VAL B CA    1 
ATOM   9863  C  C     . VAL B 2 402  ? 129.797 163.883 155.155 1.00 24.52  ? 417  VAL B C     1 
ATOM   9864  O  O     . VAL B 2 402  ? 130.347 163.886 156.261 1.00 24.52  ? 417  VAL B O     1 
ATOM   9865  C  CB    . VAL B 2 402  ? 128.567 161.730 155.625 1.00 24.52  ? 417  VAL B CB    1 
ATOM   9866  C  CG1   . VAL B 2 402  ? 127.401 162.479 156.241 1.00 24.52  ? 417  VAL B CG1   1 
ATOM   9867  C  CG2   . VAL B 2 402  ? 128.105 160.414 155.025 1.00 24.52  ? 417  VAL B CG2   1 
ATOM   9868  N  N     . THR B 2 403  ? 129.625 164.982 154.437 1.00 32.48  ? 418  THR B N     1 
ATOM   9869  C  CA    . THR B 2 403  ? 130.145 166.256 154.905 1.00 32.48  ? 418  THR B CA    1 
ATOM   9870  C  C     . THR B 2 403  ? 129.061 167.072 155.569 1.00 32.48  ? 418  THR B C     1 
ATOM   9871  O  O     . THR B 2 403  ? 127.908 166.662 155.612 1.00 32.48  ? 418  THR B O     1 
ATOM   9872  C  CB    . THR B 2 403  ? 130.756 167.072 153.759 1.00 32.48  ? 418  THR B CB    1 
ATOM   9873  O  OG1   . THR B 2 403  ? 129.819 167.150 152.679 1.00 32.48  ? 418  THR B OG1   1 
ATOM   9874  C  CG2   . THR B 2 403  ? 132.028 166.414 153.264 1.00 32.48  ? 418  THR B CG2   1 
ATOM   9875  N  N     . GLU B 2 404  ? 129.426 168.234 156.088 1.00 43.22  ? 419  GLU B N     1 
ATOM   9876  C  CA    . GLU B 2 404  ? 128.458 169.053 156.811 1.00 43.22  ? 419  GLU B CA    1 
ATOM   9877  C  C     . GLU B 2 404  ? 127.301 169.472 155.916 1.00 43.22  ? 419  GLU B C     1 
ATOM   9878  O  O     . GLU B 2 404  ? 126.176 169.648 156.398 1.00 43.22  ? 419  GLU B O     1 
ATOM   9879  C  CB    . GLU B 2 404  ? 129.146 170.282 157.406 1.00 43.22  ? 419  GLU B CB    1 
ATOM   9880  C  CG    . GLU B 2 404  ? 129.856 171.157 156.390 1.00 43.22  ? 419  GLU B CG    1 
ATOM   9881  C  CD    . GLU B 2 404  ? 130.470 172.390 157.020 1.00 43.22  ? 419  GLU B CD    1 
ATOM   9882  O  OE1   . GLU B 2 404  ? 130.467 172.487 158.265 1.00 43.22  ? 419  GLU B OE1   1 
ATOM   9883  O  OE2   . GLU B 2 404  ? 130.954 173.264 156.271 1.00 43.22  ? 419  GLU B OE2   1 
ATOM   9884  N  N     . THR B 2 405  ? 127.553 169.632 154.615 1.00 39.65  ? 420  THR B N     1 
ATOM   9885  C  CA    . THR B 2 405  ? 126.483 169.965 153.684 1.00 39.65  ? 420  THR B CA    1 
ATOM   9886  C  C     . THR B 2 405  ? 125.434 168.865 153.610 1.00 39.65  ? 420  THR B C     1 
ATOM   9887  O  O     . THR B 2 405  ? 124.290 169.137 153.229 1.00 39.65  ? 420  THR B O     1 
ATOM   9888  C  CB    . THR B 2 405  ? 127.067 170.231 152.297 1.00 39.65  ? 420  THR B CB    1 
ATOM   9889  O  OG1   . THR B 2 405  ? 128.251 171.028 152.427 1.00 39.65  ? 420  THR B OG1   1 
ATOM   9890  C  CG2   . THR B 2 405  ? 126.065 170.973 151.429 1.00 39.65  ? 420  THR B CG2   1 
ATOM   9891  N  N     . THR B 2 406  ? 125.795 167.634 153.973 1.00 36.27  ? 421  THR B N     1 
ATOM   9892  C  CA    . THR B 2 406  ? 124.817 166.553 154.003 1.00 36.27  ? 421  THR B CA    1 
ATOM   9893  C  C     . THR B 2 406  ? 123.700 166.839 154.997 1.00 36.27  ? 421  THR B C     1 
ATOM   9894  O  O     . THR B 2 406  ? 122.562 166.398 154.799 1.00 36.27  ? 421  THR B O     1 
ATOM   9895  C  CB    . THR B 2 406  ? 125.519 165.236 154.340 1.00 36.27  ? 421  THR B CB    1 
ATOM   9896  O  OG1   . THR B 2 406  ? 126.490 164.942 153.329 1.00 36.27  ? 421  THR B OG1   1 
ATOM   9897  C  CG2   . THR B 2 406  ? 124.532 164.098 154.418 1.00 36.27  ? 421  THR B CG2   1 
ATOM   9898  N  N     . LEU B 2 407  ? 123.994 167.596 156.056 1.00 43.76  ? 422  LEU B N     1 
ATOM   9899  C  CA    . LEU B 2 407  ? 122.974 167.944 157.038 1.00 43.76  ? 422  LEU B CA    1 
ATOM   9900  C  C     . LEU B 2 407  ? 121.913 168.876 156.472 1.00 43.76  ? 422  LEU B C     1 
ATOM   9901  O  O     . LEU B 2 407  ? 120.803 168.933 157.012 1.00 43.76  ? 422  LEU B O     1 
ATOM   9902  C  CB    . LEU B 2 407  ? 123.621 168.594 158.260 1.00 43.76  ? 422  LEU B CB    1 
ATOM   9903  C  CG    . LEU B 2 407  ? 124.727 167.788 158.938 1.00 43.76  ? 422  LEU B CG    1 
ATOM   9904  C  CD1   . LEU B 2 407  ? 125.318 168.560 160.105 1.00 43.76  ? 422  LEU B CD1   1 
ATOM   9905  C  CD2   . LEU B 2 407  ? 124.188 166.447 159.394 1.00 43.76  ? 422  LEU B CD2   1 
ATOM   9906  N  N     . GLU B 2 408  ? 122.226 169.611 155.406 1.00 46.18  ? 423  GLU B N     1 
ATOM   9907  C  CA    . GLU B 2 408  ? 121.296 170.586 154.846 1.00 46.18  ? 423  GLU B CA    1 
ATOM   9908  C  C     . GLU B 2 408  ? 120.331 169.941 153.855 1.00 46.18  ? 423  GLU B C     1 
ATOM   9909  O  O     . GLU B 2 408  ? 119.114 169.967 154.057 1.00 46.18  ? 423  GLU B O     1 
ATOM   9910  C  CB    . GLU B 2 408  ? 122.078 171.720 154.177 1.00 46.18  ? 423  GLU B CB    1 
ATOM   9911  C  CG    . GLU B 2 408  ? 123.187 172.285 155.043 1.00 46.18  ? 423  GLU B CG    1 
ATOM   9912  C  CD    . GLU B 2 408  ? 124.136 173.170 154.265 1.00 46.18  ? 423  GLU B CD    1 
ATOM   9913  O  OE1   . GLU B 2 408  ? 123.851 173.456 153.084 1.00 46.18  ? 423  GLU B OE1   1 
ATOM   9914  O  OE2   . GLU B 2 408  ? 125.172 173.576 154.833 1.00 46.18  ? 423  GLU B OE2   1 
ATOM   9915  N  N     . ASN B 2 409  ? 120.862 169.349 152.784 1.00 39.20  ? 424  ASN B N     1 
ATOM   9916  C  CA    . ASN B 2 409  ? 120.039 168.801 151.718 1.00 39.20  ? 424  ASN B CA    1 
ATOM   9917  C  C     . ASN B 2 409  ? 120.135 167.292 151.560 1.00 39.20  ? 424  ASN B C     1 
ATOM   9918  O  O     . ASN B 2 409  ? 119.145 166.672 151.157 1.00 39.20  ? 424  ASN B O     1 
ATOM   9919  C  CB    . ASN B 2 409  ? 120.399 169.461 150.378 1.00 39.20  ? 424  ASN B CB    1 
ATOM   9920  C  CG    . ASN B 2 409  ? 121.888 169.648 150.210 1.00 39.20  ? 424  ASN B CG    1 
ATOM   9921  O  OD1   . ASN B 2 409  ? 122.684 168.950 150.834 1.00 39.20  ? 424  ASN B OD1   1 
ATOM   9922  N  ND2   . ASN B 2 409  ? 122.276 170.600 149.371 1.00 39.20  ? 424  ASN B ND2   1 
ATOM   9923  N  N     . GLY B 2 410  ? 121.276 166.685 151.855 1.00 30.40  ? 425  GLY B N     1 
ATOM   9924  C  CA    . GLY B 2 410  ? 121.421 165.251 151.753 1.00 30.40  ? 425  GLY B CA    1 
ATOM   9925  C  C     . GLY B 2 410  ? 122.313 164.756 150.639 1.00 30.40  ? 425  GLY B C     1 
ATOM   9926  O  O     . GLY B 2 410  ? 122.176 163.598 150.234 1.00 30.40  ? 425  GLY B O     1 
ATOM   9927  N  N     . LEU B 2 411  ? 123.223 165.585 150.136 1.00 28.79  ? 426  LEU B N     1 
ATOM   9928  C  CA    . LEU B 2 411  ? 124.093 165.203 149.033 1.00 28.79  ? 426  LEU B CA    1 
ATOM   9929  C  C     . LEU B 2 411  ? 125.404 164.656 149.585 1.00 28.79  ? 426  LEU B C     1 
ATOM   9930  O  O     . LEU B 2 411  ? 126.118 165.355 150.312 1.00 28.79  ? 426  LEU B O     1 
ATOM   9931  C  CB    . LEU B 2 411  ? 124.349 166.394 148.112 1.00 28.79  ? 426  LEU B CB    1 
ATOM   9932  C  CG    . LEU B 2 411  ? 123.115 167.035 147.476 1.00 28.79  ? 426  LEU B CG    1 
ATOM   9933  C  CD1   . LEU B 2 411  ? 123.528 168.044 146.418 1.00 28.79  ? 426  LEU B CD1   1 
ATOM   9934  C  CD2   . LEU B 2 411  ? 122.195 165.978 146.888 1.00 28.79  ? 426  LEU B CD2   1 
ATOM   9935  N  N     . ILE B 2 412  ? 125.720 163.412 149.235 1.00 23.03  ? 427  ILE B N     1 
ATOM   9936  C  CA    . ILE B 2 412  ? 126.930 162.738 149.688 1.00 23.03  ? 427  ILE B CA    1 
ATOM   9937  C  C     . ILE B 2 412  ? 127.777 162.409 148.468 1.00 23.03  ? 427  ILE B C     1 
ATOM   9938  O  O     . ILE B 2 412  ? 127.262 161.902 147.464 1.00 23.03  ? 427  ILE B O     1 
ATOM   9939  C  CB    . ILE B 2 412  ? 126.608 161.474 150.505 1.00 23.03  ? 427  ILE B CB    1 
ATOM   9940  C  CG1   . ILE B 2 412  ? 125.613 160.590 149.765 1.00 23.03  ? 427  ILE B CG1   1 
ATOM   9941  C  CG2   . ILE B 2 412  ? 126.043 161.850 151.861 1.00 23.03  ? 427  ILE B CG2   1 
ATOM   9942  C  CD1   . ILE B 2 412  ? 125.075 159.472 150.604 1.00 23.03  ? 427  ILE B CD1   1 
ATOM   9943  N  N     . GLN B 2 413  ? 129.069 162.708 148.552 1.00 22.09  ? 428  GLN B N     1 
ATOM   9944  C  CA    . GLN B 2 413  ? 129.972 162.634 147.406 1.00 22.09  ? 428  GLN B CA    1 
ATOM   9945  C  C     . GLN B 2 413  ? 130.420 161.193 147.209 1.00 22.09  ? 428  GLN B C     1 
ATOM   9946  O  O     . GLN B 2 413  ? 131.531 160.807 147.572 1.00 22.09  ? 428  GLN B O     1 
ATOM   9947  C  CB    . GLN B 2 413  ? 131.158 163.563 147.612 1.00 22.09  ? 428  GLN B CB    1 
ATOM   9948  C  CG    . GLN B 2 413  ? 131.960 163.821 146.361 1.00 22.09  ? 428  GLN B CG    1 
ATOM   9949  C  CD    . GLN B 2 413  ? 133.080 164.807 146.597 1.00 22.09  ? 428  GLN B CD    1 
ATOM   9950  O  OE1   . GLN B 2 413  ? 133.586 164.930 147.712 1.00 22.09  ? 428  GLN B OE1   1 
ATOM   9951  N  NE2   . GLN B 2 413  ? 133.469 165.524 145.550 1.00 22.09  ? 428  GLN B NE2   1 
ATOM   9952  N  N     . LEU B 2 414  ? 129.543 160.387 146.620 1.00 20.36  ? 429  LEU B N     1 
ATOM   9953  C  CA    . LEU B 2 414  ? 129.852 158.992 146.343 1.00 20.36  ? 429  LEU B CA    1 
ATOM   9954  C  C     . LEU B 2 414  ? 130.899 158.877 145.241 1.00 20.36  ? 429  LEU B C     1 
ATOM   9955  O  O     . LEU B 2 414  ? 130.903 159.654 144.282 1.00 20.36  ? 429  LEU B O     1 
ATOM   9956  C  CB    . LEU B 2 414  ? 128.582 158.243 145.945 1.00 20.36  ? 429  LEU B CB    1 
ATOM   9957  C  CG    . LEU B 2 414  ? 128.726 156.758 145.631 1.00 20.36  ? 429  LEU B CG    1 
ATOM   9958  C  CD1   . LEU B 2 414  ? 129.436 156.052 146.764 1.00 20.36  ? 429  LEU B CD1   1 
ATOM   9959  C  CD2   . LEU B 2 414  ? 127.368 156.138 145.395 1.00 20.36  ? 429  LEU B CD2   1 
ATOM   9960  N  N     . ARG B 2 415  ? 131.789 157.897 145.383 1.00 20.47  ? 430  ARG B N     1 
ATOM   9961  C  CA    . ARG B 2 415  ? 132.864 157.651 144.434 1.00 20.47  ? 430  ARG B CA    1 
ATOM   9962  C  C     . ARG B 2 415  ? 132.902 156.166 144.099 1.00 20.47  ? 430  ARG B C     1 
ATOM   9963  O  O     . ARG B 2 415  ? 132.543 155.322 144.922 1.00 20.47  ? 430  ARG B O     1 
ATOM   9964  C  CB    . ARG B 2 415  ? 134.211 158.114 145.004 1.00 20.47  ? 430  ARG B CB    1 
ATOM   9965  C  CG    . ARG B 2 415  ? 135.414 157.829 144.133 1.00 20.47  ? 430  ARG B CG    1 
ATOM   9966  C  CD    . ARG B 2 415  ? 136.692 158.171 144.868 1.00 20.47  ? 430  ARG B CD    1 
ATOM   9967  N  NE    . ARG B 2 415  ? 137.885 157.863 144.091 1.00 20.47  ? 430  ARG B NE    1 
ATOM   9968  C  CZ    . ARG B 2 415  ? 138.495 156.686 144.088 1.00 20.47  ? 430  ARG B CZ    1 
ATOM   9969  N  NH1   . ARG B 2 415  ? 138.024 155.662 144.781 1.00 20.47  ? 430  ARG B NH1   1 
ATOM   9970  N  NH2   . ARG B 2 415  ? 139.606 156.532 143.374 1.00 20.47  ? 430  ARG B NH2   1 
ATOM   9971  N  N     . SER B 2 416  ? 133.329 155.853 142.879 1.00 25.11  ? 431  SER B N     1 
ATOM   9972  C  CA    . SER B 2 416  ? 133.351 154.486 142.380 1.00 25.11  ? 431  SER B CA    1 
ATOM   9973  C  C     . SER B 2 416  ? 134.780 154.076 142.055 1.00 25.11  ? 431  SER B C     1 
ATOM   9974  O  O     . SER B 2 416  ? 135.550 154.862 141.496 1.00 25.11  ? 431  SER B O     1 
ATOM   9975  C  CB    . SER B 2 416  ? 132.468 154.338 141.138 1.00 25.11  ? 431  SER B CB    1 
ATOM   9976  O  OG    . SER B 2 416  ? 132.316 152.977 140.778 1.00 25.11  ? 431  SER B OG    1 
ATOM   9977  N  N     . ARG B 2 417  ? 135.128 152.837 142.412 1.00 11.12  ? 432  ARG B N     1 
ATOM   9978  C  CA    . ARG B 2 417  ? 136.491 152.354 142.209 1.00 11.12  ? 432  ARG B CA    1 
ATOM   9979  C  C     . ARG B 2 417  ? 136.852 152.288 140.732 1.00 11.12  ? 432  ARG B C     1 
ATOM   9980  O  O     . ARG B 2 417  ? 137.955 152.685 140.340 1.00 11.12  ? 432  ARG B O     1 
ATOM   9981  C  CB    . ARG B 2 417  ? 136.654 150.979 142.852 1.00 11.12  ? 432  ARG B CB    1 
ATOM   9982  C  CG    . ARG B 2 417  ? 138.000 150.318 142.606 1.00 11.12  ? 432  ARG B CG    1 
ATOM   9983  C  CD    . ARG B 2 417  ? 137.931 148.838 142.925 1.00 11.12  ? 432  ARG B CD    1 
ATOM   9984  N  NE    . ARG B 2 417  ? 137.045 148.138 142.006 1.00 11.12  ? 432  ARG B NE    1 
ATOM   9985  C  CZ    . ARG B 2 417  ? 136.480 146.967 142.256 1.00 11.12  ? 432  ARG B CZ    1 
ATOM   9986  N  NH1   . ARG B 2 417  ? 136.662 146.344 143.406 1.00 11.12  ? 432  ARG B NH1   1 
ATOM   9987  N  NH2   . ARG B 2 417  ? 135.708 146.408 141.330 1.00 11.12  ? 432  ARG B NH2   1 
ATOM   9988  N  N     . ASP B 2 418  ? 135.940 151.778 139.902 1.00 25.16  ? 433  ASP B N     1 
ATOM   9989  C  CA    . ASP B 2 418  ? 136.254 151.527 138.499 1.00 25.16  ? 433  ASP B CA    1 
ATOM   9990  C  C     . ASP B 2 418  ? 136.581 152.818 137.762 1.00 25.16  ? 433  ASP B C     1 
ATOM   9991  O  O     . ASP B 2 418  ? 137.608 152.917 137.083 1.00 25.16  ? 433  ASP B O     1 
ATOM   9992  C  CB    . ASP B 2 418  ? 135.085 150.808 137.832 1.00 25.16  ? 433  ASP B CB    1 
ATOM   9993  C  CG    . ASP B 2 418  ? 134.850 149.427 138.404 1.00 25.16  ? 433  ASP B CG    1 
ATOM   9994  O  OD1   . ASP B 2 418  ? 135.822 148.653 138.505 1.00 25.16  ? 433  ASP B OD1   1 
ATOM   9995  O  OD2   . ASP B 2 418  ? 133.695 149.118 138.764 1.00 25.16  ? 433  ASP B OD2   1 
ATOM   9996  N  N     . THR B 2 419  ? 135.717 153.820 137.882 1.00 22.46  ? 434  THR B N     1 
ATOM   9997  C  CA    . THR B 2 419  ? 135.889 155.058 137.136 1.00 22.46  ? 434  THR B CA    1 
ATOM   9998  C  C     . THR B 2 419  ? 136.683 156.110 137.898 1.00 22.46  ? 434  THR B C     1 
ATOM   9999  O  O     . THR B 2 419  ? 137.362 156.929 137.269 1.00 22.46  ? 434  THR B O     1 
ATOM   10000 C  CB    . THR B 2 419  ? 134.523 155.629 136.758 1.00 22.46  ? 434  THR B CB    1 
ATOM   10001 O  OG1   . THR B 2 419  ? 134.036 156.441 137.830 1.00 22.46  ? 434  THR B OG1   1 
ATOM   10002 C  CG2   . THR B 2 419  ? 133.536 154.502 136.516 1.00 22.46  ? 434  THR B CG2   1 
ATOM   10003 N  N     . THR B 2 420  ? 136.609 156.102 139.232 1.00 38.40  ? 435  THR B N     1 
ATOM   10004 C  CA    . THR B 2 420  ? 137.236 157.114 140.090 1.00 38.40  ? 435  THR B CA    1 
ATOM   10005 C  C     . THR B 2 420  ? 136.654 158.502 139.834 1.00 38.40  ? 435  THR B C     1 
ATOM   10006 O  O     . THR B 2 420  ? 137.374 159.501 139.802 1.00 38.40  ? 435  THR B O     1 
ATOM   10007 C  CB    . THR B 2 420  ? 138.760 157.136 139.939 1.00 38.40  ? 435  THR B CB    1 
ATOM   10008 O  OG1   . THR B 2 420  ? 139.112 157.633 138.644 1.00 38.40  ? 435  THR B OG1   1 
ATOM   10009 C  CG2   . THR B 2 420  ? 139.334 155.744 140.120 1.00 38.40  ? 435  THR B CG2   1 
ATOM   10010 N  N     . MET B 2 421  ? 135.337 158.565 139.661 1.00 24.65  ? 436  MET B N     1 
ATOM   10011 C  CA    . MET B 2 421  ? 134.625 159.813 139.428 1.00 24.65  ? 436  MET B CA    1 
ATOM   10012 C  C     . MET B 2 421  ? 133.576 159.999 140.515 1.00 24.65  ? 436  MET B C     1 
ATOM   10013 O  O     . MET B 2 421  ? 132.888 159.047 140.895 1.00 24.65  ? 436  MET B O     1 
ATOM   10014 C  CB    . MET B 2 421  ? 133.972 159.829 138.042 1.00 24.65  ? 436  MET B CB    1 
ATOM   10015 C  CG    . MET B 2 421  ? 134.931 159.606 136.876 1.00 24.65  ? 436  MET B CG    1 
ATOM   10016 S  SD    . MET B 2 421  ? 135.576 161.124 136.150 1.00 24.65  ? 436  MET B SD    1 
ATOM   10017 C  CE    . MET B 2 421  ? 136.944 161.489 137.240 1.00 24.65  ? 436  MET B CE    1 
ATOM   10018 N  N     . LYS B 2 422  ? 133.449 161.232 140.999 1.00 19.69  ? 437  LYS B N     1 
ATOM   10019 C  CA    . LYS B 2 422  ? 132.679 161.536 142.197 1.00 19.69  ? 437  LYS B CA    1 
ATOM   10020 C  C     . LYS B 2 422  ? 131.281 162.014 141.839 1.00 19.69  ? 437  LYS B C     1 
ATOM   10021 O  O     . LYS B 2 422  ? 131.120 162.933 141.030 1.00 19.69  ? 437  LYS B O     1 
ATOM   10022 C  CB    . LYS B 2 422  ? 133.389 162.599 143.032 1.00 19.69  ? 437  LYS B CB    1 
ATOM   10023 C  CG    . LYS B 2 422  ? 134.830 162.265 143.327 1.00 19.69  ? 437  LYS B CG    1 
ATOM   10024 C  CD    . LYS B 2 422  ? 135.534 163.426 143.982 1.00 19.69  ? 437  LYS B CD    1 
ATOM   10025 C  CE    . LYS B 2 422  ? 137.007 163.130 144.147 1.00 19.69  ? 437  LYS B CE    1 
ATOM   10026 N  NZ    . LYS B 2 422  ? 137.652 162.848 142.839 1.00 19.69  ? 437  LYS B NZ    1 
ATOM   10027 N  N     . GLU B 2 423  ? 130.280 161.396 142.454 1.00 24.60  ? 438  GLU B N     1 
ATOM   10028 C  CA    . GLU B 2 423  ? 128.889 161.784 142.295 1.00 24.60  ? 438  GLU B CA    1 
ATOM   10029 C  C     . GLU B 2 423  ? 128.494 162.760 143.403 1.00 24.60  ? 438  GLU B C     1 
ATOM   10030 O  O     . GLU B 2 423  ? 129.313 163.161 144.234 1.00 24.60  ? 438  GLU B O     1 
ATOM   10031 C  CB    . GLU B 2 423  ? 127.996 160.547 142.309 1.00 24.60  ? 438  GLU B CB    1 
ATOM   10032 C  CG    . GLU B 2 423  ? 128.294 159.544 141.219 1.00 24.60  ? 438  GLU B CG    1 
ATOM   10033 C  CD    . GLU B 2 423  ? 127.617 159.894 139.915 1.00 24.60  ? 438  GLU B CD    1 
ATOM   10034 O  OE1   . GLU B 2 423  ? 127.915 160.969 139.354 1.00 24.60  ? 438  GLU B OE1   1 
ATOM   10035 O  OE2   . GLU B 2 423  ? 126.774 159.097 139.458 1.00 24.60  ? 438  GLU B OE2   1 
ATOM   10036 N  N     . MET B 2 424  ? 127.223 163.150 143.422 1.00 24.64  ? 439  MET B N     1 
ATOM   10037 C  CA    . MET B 2 424  ? 126.642 163.940 144.502 1.00 24.64  ? 439  MET B CA    1 
ATOM   10038 C  C     . MET B 2 424  ? 125.269 163.380 144.850 1.00 24.64  ? 439  MET B C     1 
ATOM   10039 O  O     . MET B 2 424  ? 124.296 164.111 145.031 1.00 24.64  ? 439  MET B O     1 
ATOM   10040 C  CB    . MET B 2 424  ? 126.559 165.417 144.125 1.00 24.64  ? 439  MET B CB    1 
ATOM   10041 C  CG    . MET B 2 424  ? 127.896 166.130 144.106 1.00 24.64  ? 439  MET B CG    1 
ATOM   10042 S  SD    . MET B 2 424  ? 128.664 166.193 145.733 1.00 24.64  ? 439  MET B SD    1 
ATOM   10043 C  CE    . MET B 2 424  ? 130.183 167.059 145.354 1.00 24.64  ? 439  MET B CE    1 
ATOM   10044 N  N     . MET B 2 425  ? 125.188 162.057 144.936 1.00 23.67  ? 440  MET B N     1 
ATOM   10045 C  CA    . MET B 2 425  ? 123.911 161.379 145.117 1.00 23.67  ? 440  MET B CA    1 
ATOM   10046 C  C     . MET B 2 425  ? 123.249 161.772 146.433 1.00 23.67  ? 440  MET B C     1 
ATOM   10047 O  O     . MET B 2 425  ? 123.914 161.940 147.459 1.00 23.67  ? 440  MET B O     1 
ATOM   10048 C  CB    . MET B 2 425  ? 124.125 159.868 145.058 1.00 23.67  ? 440  MET B CB    1 
ATOM   10049 C  CG    . MET B 2 425  ? 122.923 159.041 145.446 1.00 23.67  ? 440  MET B CG    1 
ATOM   10050 S  SD    . MET B 2 425  ? 123.174 157.309 145.045 1.00 23.67  ? 440  MET B SD    1 
ATOM   10051 C  CE    . MET B 2 425  ? 123.328 157.414 143.266 1.00 23.67  ? 440  MET B CE    1 
ATOM   10052 N  N     . HIS B 2 426  ? 121.929 161.931 146.392 1.00 28.09  ? 441  HIS B N     1 
ATOM   10053 C  CA    . HIS B 2 426  ? 121.144 162.230 147.580 1.00 28.09  ? 441  HIS B CA    1 
ATOM   10054 C  C     . HIS B 2 426  ? 121.061 161.005 148.486 1.00 28.09  ? 441  HIS B C     1 
ATOM   10055 O  O     . HIS B 2 426  ? 121.159 159.863 148.029 1.00 28.09  ? 441  HIS B O     1 
ATOM   10056 C  CB    . HIS B 2 426  ? 119.742 162.696 147.183 1.00 28.09  ? 441  HIS B CB    1 
ATOM   10057 C  CG    . HIS B 2 426  ? 118.877 163.092 148.339 1.00 28.09  ? 441  HIS B CG    1 
ATOM   10058 N  ND1   . HIS B 2 426  ? 117.994 162.221 148.940 1.00 28.09  ? 441  HIS B ND1   1 
ATOM   10059 C  CD2   . HIS B 2 426  ? 118.754 164.267 148.999 1.00 28.09  ? 441  HIS B CD2   1 
ATOM   10060 C  CE1   . HIS B 2 426  ? 117.368 162.841 149.924 1.00 28.09  ? 441  HIS B CE1   1 
ATOM   10061 N  NE2   . HIS B 2 426  ? 117.810 164.084 149.981 1.00 28.09  ? 441  HIS B NE2   1 
ATOM   10062 N  N     . ILE B 2 427  ? 120.878 161.258 149.787 1.00 27.14  ? 442  ILE B N     1 
ATOM   10063 C  CA    . ILE B 2 427  ? 120.905 160.182 150.780 1.00 27.14  ? 442  ILE B CA    1 
ATOM   10064 C  C     . ILE B 2 427  ? 119.849 159.131 150.470 1.00 27.14  ? 442  ILE B C     1 
ATOM   10065 O  O     . ILE B 2 427  ? 120.118 157.924 150.502 1.00 27.14  ? 442  ILE B O     1 
ATOM   10066 C  CB    . ILE B 2 427  ? 120.703 160.749 152.196 1.00 27.14  ? 442  ILE B CB    1 
ATOM   10067 C  CG1   . ILE B 2 427  ? 121.918 161.543 152.654 1.00 27.14  ? 442  ILE B CG1   1 
ATOM   10068 C  CG2   . ILE B 2 427  ? 120.427 159.626 153.176 1.00 27.14  ? 442  ILE B CG2   1 
ATOM   10069 C  CD1   . ILE B 2 427  ? 121.780 162.020 154.077 1.00 27.14  ? 442  ILE B CD1   1 
ATOM   10070 N  N     . SER B 2 428  ? 118.625 159.577 150.178 1.00 28.18  ? 443  SER B N     1 
ATOM   10071 C  CA    . SER B 2 428  ? 117.514 158.649 150.003 1.00 28.18  ? 443  SER B CA    1 
ATOM   10072 C  C     . SER B 2 428  ? 117.769 157.660 148.877 1.00 28.18  ? 443  SER B C     1 
ATOM   10073 O  O     . SER B 2 428  ? 117.186 156.570 148.861 1.00 28.18  ? 443  SER B O     1 
ATOM   10074 C  CB    . SER B 2 428  ? 116.223 159.424 149.739 1.00 28.18  ? 443  SER B CB    1 
ATOM   10075 O  OG    . SER B 2 428  ? 115.900 160.255 150.837 1.00 28.18  ? 443  SER B OG    1 
ATOM   10076 N  N     . LYS B 2 429  ? 118.632 158.018 147.931 1.00 27.76  ? 444  LYS B N     1 
ATOM   10077 C  CA    . LYS B 2 429  ? 118.925 157.159 146.796 1.00 27.76  ? 444  LYS B CA    1 
ATOM   10078 C  C     . LYS B 2 429  ? 120.131 156.257 147.011 1.00 27.76  ? 444  LYS B C     1 
ATOM   10079 O  O     . LYS B 2 429  ? 120.352 155.359 146.197 1.00 27.76  ? 444  LYS B O     1 
ATOM   10080 C  CB    . LYS B 2 429  ? 119.171 158.007 145.546 1.00 27.76  ? 444  LYS B CB    1 
ATOM   10081 C  CG    . LYS B 2 429  ? 118.239 159.188 145.387 1.00 27.76  ? 444  LYS B CG    1 
ATOM   10082 C  CD    . LYS B 2 429  ? 118.717 160.075 144.255 1.00 27.76  ? 444  LYS B CD    1 
ATOM   10083 C  CE    . LYS B 2 429  ? 117.955 161.381 144.212 1.00 27.76  ? 444  LYS B CE    1 
ATOM   10084 N  NZ    . LYS B 2 429  ? 118.519 162.295 143.184 1.00 27.76  ? 444  LYS B NZ    1 
ATOM   10085 N  N     . LEU B 2 430  ? 120.914 156.470 148.072 1.00 22.17  ? 445  LEU B N     1 
ATOM   10086 C  CA    . LEU B 2 430  ? 122.199 155.784 148.187 1.00 22.17  ? 445  LEU B CA    1 
ATOM   10087 C  C     . LEU B 2 430  ? 122.021 154.283 148.367 1.00 22.17  ? 445  LEU B C     1 
ATOM   10088 O  O     . LEU B 2 430  ? 122.636 153.485 147.649 1.00 22.17  ? 445  LEU B O     1 
ATOM   10089 C  CB    . LEU B 2 430  ? 123.003 156.363 149.349 1.00 22.17  ? 445  LEU B CB    1 
ATOM   10090 C  CG    . LEU B 2 430  ? 124.433 155.839 149.468 1.00 22.17  ? 445  LEU B CG    1 
ATOM   10091 C  CD1   . LEU B 2 430  ? 125.342 156.570 148.496 1.00 22.17  ? 445  LEU B CD1   1 
ATOM   10092 C  CD2   . LEU B 2 430  ? 124.951 155.949 150.892 1.00 22.17  ? 445  LEU B CD2   1 
ATOM   10093 N  N     . ARG B 2 431  ? 121.193 153.879 149.329 1.00 23.51  ? 446  ARG B N     1 
ATOM   10094 C  CA    . ARG B 2 431  ? 121.019 152.457 149.597 1.00 23.51  ? 446  ARG B CA    1 
ATOM   10095 C  C     . ARG B 2 431  ? 120.401 151.746 148.405 1.00 23.51  ? 446  ARG B C     1 
ATOM   10096 O  O     . ARG B 2 431  ? 120.825 150.642 148.038 1.00 23.51  ? 446  ARG B O     1 
ATOM   10097 C  CB    . ARG B 2 431  ? 120.164 152.261 150.846 1.00 23.51  ? 446  ARG B CB    1 
ATOM   10098 C  CG    . ARG B 2 431  ? 119.738 150.831 151.081 1.00 23.51  ? 446  ARG B CG    1 
ATOM   10099 C  CD    . ARG B 2 431  ? 118.245 150.693 150.900 1.00 23.51  ? 446  ARG B CD    1 
ATOM   10100 N  NE    . ARG B 2 431  ? 117.518 151.613 151.765 1.00 23.51  ? 446  ARG B NE    1 
ATOM   10101 C  CZ    . ARG B 2 431  ? 116.205 151.789 151.735 1.00 23.51  ? 446  ARG B CZ    1 
ATOM   10102 N  NH1   . ARG B 2 431  ? 115.438 151.123 150.888 1.00 23.51  ? 446  ARG B NH1   1 
ATOM   10103 N  NH2   . ARG B 2 431  ? 115.647 152.657 152.574 1.00 23.51  ? 446  ARG B NH2   1 
ATOM   10104 N  N     . ASP B 2 432  ? 119.402 152.368 147.779 1.00 22.63  ? 447  ASP B N     1 
ATOM   10105 C  CA    . ASP B 2 432  ? 118.766 151.750 146.622 1.00 22.63  ? 447  ASP B CA    1 
ATOM   10106 C  C     . ASP B 2 432  ? 119.737 151.638 145.456 1.00 22.63  ? 447  ASP B C     1 
ATOM   10107 O  O     . ASP B 2 432  ? 119.747 150.627 144.747 1.00 22.63  ? 447  ASP B O     1 
ATOM   10108 C  CB    . ASP B 2 432  ? 117.525 152.540 146.217 1.00 22.63  ? 447  ASP B CB    1 
ATOM   10109 C  CG    . ASP B 2 432  ? 116.548 151.709 145.414 1.00 22.63  ? 447  ASP B CG    1 
ATOM   10110 O  OD1   . ASP B 2 432  ? 116.839 150.517 145.174 1.00 22.63  ? 447  ASP B OD1   1 
ATOM   10111 O  OD2   . ASP B 2 432  ? 115.487 152.243 145.029 1.00 22.63  ? 447  ASP B OD2   1 
ATOM   10112 N  N     . PHE B 2 433  ? 120.568 152.662 145.246 1.00 20.29  ? 448  PHE B N     1 
ATOM   10113 C  CA    . PHE B 2 433  ? 121.562 152.614 144.182 1.00 20.29  ? 448  PHE B CA    1 
ATOM   10114 C  C     . PHE B 2 433  ? 122.577 151.508 144.424 1.00 20.29  ? 448  PHE B C     1 
ATOM   10115 O  O     . PHE B 2 433  ? 122.950 150.787 143.493 1.00 20.29  ? 448  PHE B O     1 
ATOM   10116 C  CB    . PHE B 2 433  ? 122.253 153.970 144.068 1.00 20.29  ? 448  PHE B CB    1 
ATOM   10117 C  CG    . PHE B 2 433  ? 123.515 153.948 143.260 1.00 20.29  ? 448  PHE B CG    1 
ATOM   10118 C  CD1   . PHE B 2 433  ? 123.472 153.984 141.879 1.00 20.29  ? 448  PHE B CD1   1 
ATOM   10119 C  CD2   . PHE B 2 433  ? 124.749 153.916 143.885 1.00 20.29  ? 448  PHE B CD2   1 
ATOM   10120 C  CE1   . PHE B 2 433  ? 124.635 153.973 141.138 1.00 20.29  ? 448  PHE B CE1   1 
ATOM   10121 C  CE2   . PHE B 2 433  ? 125.912 153.903 143.149 1.00 20.29  ? 448  PHE B CE2   1 
ATOM   10122 C  CZ    . PHE B 2 433  ? 125.856 153.933 141.774 1.00 20.29  ? 448  PHE B CZ    1 
ATOM   10123 N  N     . LEU B 2 434  ? 123.042 151.363 145.667 1.00 20.12  ? 449  LEU B N     1 
ATOM   10124 C  CA    . LEU B 2 434  ? 124.000 150.303 145.967 1.00 20.12  ? 449  LEU B CA    1 
ATOM   10125 C  C     . LEU B 2 434  ? 123.379 148.926 145.775 1.00 20.12  ? 449  LEU B C     1 
ATOM   10126 O  O     . LEU B 2 434  ? 124.019 148.024 145.221 1.00 20.12  ? 449  LEU B O     1 
ATOM   10127 C  CB    . LEU B 2 434  ? 124.536 150.455 147.390 1.00 20.12  ? 449  LEU B CB    1 
ATOM   10128 C  CG    . LEU B 2 434  ? 125.291 151.745 147.713 1.00 20.12  ? 449  LEU B CG    1 
ATOM   10129 C  CD1   . LEU B 2 434  ? 125.783 151.729 149.146 1.00 20.12  ? 449  LEU B CD1   1 
ATOM   10130 C  CD2   . LEU B 2 434  ? 126.442 151.967 146.752 1.00 20.12  ? 449  LEU B CD2   1 
ATOM   10131 N  N     . VAL B 2 435  ? 122.132 148.745 146.215 1.00 18.91  ? 450  VAL B N     1 
ATOM   10132 C  CA    . VAL B 2 435  ? 121.472 147.455 146.031 1.00 18.91  ? 450  VAL B CA    1 
ATOM   10133 C  C     . VAL B 2 435  ? 121.288 147.156 144.549 1.00 18.91  ? 450  VAL B C     1 
ATOM   10134 O  O     . VAL B 2 435  ? 121.520 146.029 144.096 1.00 18.91  ? 450  VAL B O     1 
ATOM   10135 C  CB    . VAL B 2 435  ? 120.132 147.418 146.787 1.00 18.91  ? 450  VAL B CB    1 
ATOM   10136 C  CG1   . VAL B 2 435  ? 119.369 146.151 146.445 1.00 18.91  ? 450  VAL B CG1   1 
ATOM   10137 C  CG2   . VAL B 2 435  ? 120.366 147.499 148.282 1.00 18.91  ? 450  VAL B CG2   1 
ATOM   10138 N  N     . LYS B 2 436  ? 120.872 148.157 143.770 1.00 20.45  ? 451  LYS B N     1 
ATOM   10139 C  CA    . LYS B 2 436  ? 120.687 147.948 142.338 1.00 20.45  ? 451  LYS B CA    1 
ATOM   10140 C  C     . LYS B 2 436  ? 122.004 147.602 141.657 1.00 20.45  ? 451  LYS B C     1 
ATOM   10141 O  O     . LYS B 2 436  ? 122.056 146.704 140.808 1.00 20.45  ? 451  LYS B O     1 
ATOM   10142 C  CB    . LYS B 2 436  ? 120.071 149.193 141.703 1.00 20.45  ? 451  LYS B CB    1 
ATOM   10143 C  CG    . LYS B 2 436  ? 119.231 148.907 140.472 1.00 20.45  ? 451  LYS B CG    1 
ATOM   10144 C  CD    . LYS B 2 436  ? 119.344 150.024 139.448 1.00 20.45  ? 451  LYS B CD    1 
ATOM   10145 C  CE    . LYS B 2 436  ? 119.126 151.390 140.072 1.00 20.45  ? 451  LYS B CE    1 
ATOM   10146 N  NZ    . LYS B 2 436  ? 119.392 152.480 139.093 1.00 20.45  ? 451  LYS B NZ    1 
ATOM   10147 N  N     . TYR B 2 437  ? 123.079 148.306 142.017 1.00 18.34  ? 452  TYR B N     1 
ATOM   10148 C  CA    . TYR B 2 437  ? 124.385 148.026 141.433 1.00 18.34  ? 452  TYR B CA    1 
ATOM   10149 C  C     . TYR B 2 437  ? 124.839 146.610 141.761 1.00 18.34  ? 452  TYR B C     1 
ATOM   10150 O  O     . TYR B 2 437  ? 125.303 145.873 140.882 1.00 18.34  ? 452  TYR B O     1 
ATOM   10151 C  CB    . TYR B 2 437  ? 125.403 149.050 141.931 1.00 18.34  ? 452  TYR B CB    1 
ATOM   10152 C  CG    . TYR B 2 437  ? 126.765 148.924 141.298 1.00 18.34  ? 452  TYR B CG    1 
ATOM   10153 C  CD1   . TYR B 2 437  ? 127.686 148.000 141.764 1.00 18.34  ? 452  TYR B CD1   1 
ATOM   10154 C  CD2   . TYR B 2 437  ? 127.135 149.735 140.239 1.00 18.34  ? 452  TYR B CD2   1 
ATOM   10155 C  CE1   . TYR B 2 437  ? 128.930 147.881 141.190 1.00 18.34  ? 452  TYR B CE1   1 
ATOM   10156 C  CE2   . TYR B 2 437  ? 128.381 149.626 139.661 1.00 18.34  ? 452  TYR B CE2   1 
ATOM   10157 C  CZ    . TYR B 2 437  ? 129.273 148.696 140.140 1.00 18.34  ? 452  TYR B CZ    1 
ATOM   10158 O  OH    . TYR B 2 437  ? 130.518 148.578 139.568 1.00 18.34  ? 452  TYR B OH    1 
ATOM   10159 N  N     . LEU B 2 438  ? 124.708 146.208 143.026 1.00 20.21  ? 453  LEU B N     1 
ATOM   10160 C  CA    . LEU B 2 438  ? 125.164 144.887 143.435 1.00 20.21  ? 453  LEU B CA    1 
ATOM   10161 C  C     . LEU B 2 438  ? 124.226 143.774 142.994 1.00 20.21  ? 453  LEU B C     1 
ATOM   10162 O  O     . LEU B 2 438  ? 124.598 142.601 143.089 1.00 20.21  ? 453  LEU B O     1 
ATOM   10163 C  CB    . LEU B 2 438  ? 125.348 144.840 144.954 1.00 20.21  ? 453  LEU B CB    1 
ATOM   10164 C  CG    . LEU B 2 438  ? 126.355 145.834 145.543 1.00 20.21  ? 453  LEU B CG    1 
ATOM   10165 C  CD1   . LEU B 2 438  ? 126.585 145.557 147.019 1.00 20.21  ? 453  LEU B CD1   1 
ATOM   10166 C  CD2   . LEU B 2 438  ? 127.666 145.813 144.775 1.00 20.21  ? 453  LEU B CD2   1 
ATOM   10167 N  N     . ALA B 2 439  ? 123.024 144.106 142.530 1.00 21.73  ? 454  ALA B N     1 
ATOM   10168 C  CA    . ALA B 2 439  ? 122.167 143.111 141.900 1.00 21.73  ? 454  ALA B CA    1 
ATOM   10169 C  C     . ALA B 2 439  ? 122.420 142.998 140.405 1.00 21.73  ? 454  ALA B C     1 
ATOM   10170 O  O     . ALA B 2 439  ? 122.240 141.918 139.833 1.00 21.73  ? 454  ALA B O     1 
ATOM   10171 C  CB    . ALA B 2 439  ? 120.693 143.445 142.147 1.00 21.73  ? 454  ALA B CB    1 
ATOM   10172 N  N     . SER B 2 440  ? 122.830 144.094 139.762 1.00 21.68  ? 455  SER B N     1 
ATOM   10173 C  CA    . SER B 2 440  ? 123.195 144.038 138.352 1.00 21.68  ? 455  SER B CA    1 
ATOM   10174 C  C     . SER B 2 440  ? 124.548 143.374 138.141 1.00 21.68  ? 455  SER B C     1 
ATOM   10175 O  O     . SER B 2 440  ? 124.739 142.676 137.140 1.00 21.68  ? 455  SER B O     1 
ATOM   10176 C  CB    . SER B 2 440  ? 123.218 145.443 137.753 1.00 21.68  ? 455  SER B CB    1 
ATOM   10177 O  OG    . SER B 2 440  ? 124.445 146.087 138.045 1.00 21.68  ? 455  SER B OG    1 
ATOM   10178 N  N     . ALA B 2 441  ? 125.496 143.589 139.058 1.00 21.17  ? 456  ALA B N     1 
ATOM   10179 C  CA    . ALA B 2 441  ? 126.810 142.969 138.921 1.00 21.17  ? 456  ALA B CA    1 
ATOM   10180 C  C     . ALA B 2 441  ? 126.723 141.449 139.006 1.00 21.17  ? 456  ALA B C     1 
ATOM   10181 O  O     . ALA B 2 441  ? 127.400 140.740 138.253 1.00 21.17  ? 456  ALA B O     1 
ATOM   10182 C  CB    . ALA B 2 441  ? 127.762 143.511 139.985 1.00 21.17  ? 456  ALA B CB    1 
ATOM   10183 N  N     . SER B 2 442  ? 125.899 140.931 139.914 1.00 26.30  ? 457  SER B N     1 
ATOM   10184 C  CA    . SER B 2 442  ? 125.767 139.491 140.088 1.00 26.30  ? 457  SER B CA    1 
ATOM   10185 C  C     . SER B 2 442  ? 124.934 138.827 139.001 1.00 26.30  ? 457  SER B C     1 
ATOM   10186 O  O     . SER B 2 442  ? 124.907 137.593 138.936 1.00 26.30  ? 457  SER B O     1 
ATOM   10187 C  CB    . SER B 2 442  ? 125.155 139.180 141.456 1.00 26.30  ? 457  SER B CB    1 
ATOM   10188 O  OG    . SER B 2 442  ? 124.995 137.784 141.632 1.00 26.30  ? 457  SER B OG    1 
ATOM   10189 N  N     . ASN B 2 443  ? 124.262 139.599 138.155 1.00 29.51  ? 458  ASN B N     1 
ATOM   10190 C  CA    . ASN B 2 443  ? 123.424 139.028 137.108 1.00 29.51  ? 458  ASN B CA    1 
ATOM   10191 C  C     . ASN B 2 443  ? 123.819 139.562 135.736 1.00 29.51  ? 458  ASN B C     1 
ATOM   10192 O  O     . ASN B 2 443  ? 124.873 139.213 135.205 1.00 29.51  ? 458  ASN B O     1 
ATOM   10193 C  CB    . ASN B 2 443  ? 121.949 139.321 137.386 1.00 29.51  ? 458  ASN B CB    1 
ATOM   10194 C  CG    . ASN B 2 443  ? 121.493 138.797 138.736 1.00 29.51  ? 458  ASN B CG    1 
ATOM   10195 O  OD1   . ASN B 2 443  ? 120.974 137.686 138.840 1.00 29.51  ? 458  ASN B OD1   1 
ATOM   10196 N  ND2   . ASN B 2 443  ? 121.688 139.597 139.778 1.00 29.51  ? 458  ASN B ND2   1 
ATOM   10197 N  N     . ALA C 2 27   ? 108.391 111.697 169.859 1.00 87.39  ? 42   ALA C N     1 
ATOM   10198 C  CA    . ALA C 2 27   ? 109.347 112.596 170.493 1.00 87.39  ? 42   ALA C CA    1 
ATOM   10199 C  C     . ALA C 2 27   ? 110.008 113.507 169.464 1.00 87.39  ? 42   ALA C C     1 
ATOM   10200 O  O     . ALA C 2 27   ? 109.725 113.418 168.269 1.00 87.39  ? 42   ALA C O     1 
ATOM   10201 C  CB    . ALA C 2 27   ? 110.399 111.802 171.252 1.00 87.39  ? 42   ALA C CB    1 
ATOM   10202 N  N     . LEU C 2 28   ? 110.891 114.387 169.939 1.00 77.59  ? 43   LEU C N     1 
ATOM   10203 C  CA    . LEU C 2 28   ? 111.571 115.322 169.051 1.00 77.59  ? 43   LEU C CA    1 
ATOM   10204 C  C     . LEU C 2 28   ? 112.679 114.656 168.247 1.00 77.59  ? 43   LEU C C     1 
ATOM   10205 O  O     . LEU C 2 28   ? 112.906 115.029 167.090 1.00 77.59  ? 43   LEU C O     1 
ATOM   10206 C  CB    . LEU C 2 28   ? 112.145 116.489 169.855 1.00 77.59  ? 43   LEU C CB    1 
ATOM   10207 C  CG    . LEU C 2 28   ? 113.044 117.454 169.079 1.00 77.59  ? 43   LEU C CG    1 
ATOM   10208 C  CD1   . LEU C 2 28   ? 112.268 118.137 167.964 1.00 77.59  ? 43   LEU C CD1   1 
ATOM   10209 C  CD2   . LEU C 2 28   ? 113.668 118.477 170.003 1.00 77.59  ? 43   LEU C CD2   1 
ATOM   10210 N  N     . VAL C 2 29   ? 113.378 113.683 168.836 1.00 76.59  ? 44   VAL C N     1 
ATOM   10211 C  CA    . VAL C 2 29   ? 114.507 113.060 168.151 1.00 76.59  ? 44   VAL C CA    1 
ATOM   10212 C  C     . VAL C 2 29   ? 114.042 112.365 166.879 1.00 76.59  ? 44   VAL C C     1 
ATOM   10213 O  O     . VAL C 2 29   ? 114.700 112.445 165.836 1.00 76.59  ? 44   VAL C O     1 
ATOM   10214 C  CB    . VAL C 2 29   ? 115.236 112.088 169.097 1.00 76.59  ? 44   VAL C CB    1 
ATOM   10215 C  CG1   . VAL C 2 29   ? 116.411 111.436 168.385 1.00 76.59  ? 44   VAL C CG1   1 
ATOM   10216 C  CG2   . VAL C 2 29   ? 115.705 112.817 170.347 1.00 76.59  ? 44   VAL C CG2   1 
ATOM   10217 N  N     . ASP C 2 30   ? 112.898 111.679 166.941 1.00 79.94  ? 45   ASP C N     1 
ATOM   10218 C  CA    . ASP C 2 30   ? 112.357 111.034 165.748 1.00 79.94  ? 45   ASP C CA    1 
ATOM   10219 C  C     . ASP C 2 30   ? 112.020 112.054 164.668 1.00 79.94  ? 45   ASP C C     1 
ATOM   10220 O  O     . ASP C 2 30   ? 112.306 111.835 163.484 1.00 79.94  ? 45   ASP C O     1 
ATOM   10221 C  CB    . ASP C 2 30   ? 111.120 110.213 166.111 1.00 79.94  ? 45   ASP C CB    1 
ATOM   10222 C  CG    . ASP C 2 30   ? 110.315 109.805 164.894 1.00 79.94  ? 45   ASP C CG    1 
ATOM   10223 O  OD1   . ASP C 2 30   ? 110.821 108.999 164.086 1.00 79.94  ? 45   ASP C OD1   1 
ATOM   10224 O  OD2   . ASP C 2 30   ? 109.174 110.292 164.745 1.00 79.94  ? 45   ASP C OD2   1 
ATOM   10225 N  N     . LEU C 2 31   ? 111.407 113.175 165.058 1.00 73.72  ? 46   LEU C N     1 
ATOM   10226 C  CA    . LEU C 2 31   ? 111.037 114.196 164.083 1.00 73.72  ? 46   LEU C CA    1 
ATOM   10227 C  C     . LEU C 2 31   ? 112.269 114.810 163.431 1.00 73.72  ? 46   LEU C C     1 
ATOM   10228 O  O     . LEU C 2 31   ? 112.279 115.067 162.222 1.00 73.72  ? 46   LEU C O     1 
ATOM   10229 C  CB    . LEU C 2 31   ? 110.188 115.275 164.752 1.00 73.72  ? 46   LEU C CB    1 
ATOM   10230 C  CG    . LEU C 2 31   ? 109.541 116.292 163.812 1.00 73.72  ? 46   LEU C CG    1 
ATOM   10231 C  CD1   . LEU C 2 31   ? 108.629 115.584 162.826 1.00 73.72  ? 46   LEU C CD1   1 
ATOM   10232 C  CD2   . LEU C 2 31   ? 108.773 117.340 164.600 1.00 73.72  ? 46   LEU C CD2   1 
ATOM   10233 N  N     . CYS C 2 32   ? 113.316 115.063 164.219 1.00 67.86  ? 47   CYS C N     1 
ATOM   10234 C  CA    . CYS C 2 32   ? 114.549 115.595 163.650 1.00 67.86  ? 47   CYS C CA    1 
ATOM   10235 C  C     . CYS C 2 32   ? 115.228 114.571 162.749 1.00 67.86  ? 47   CYS C C     1 
ATOM   10236 O  O     . CYS C 2 32   ? 115.813 114.931 161.721 1.00 67.86  ? 47   CYS C O     1 
ATOM   10237 C  CB    . CYS C 2 32   ? 115.493 116.042 164.765 1.00 67.86  ? 47   CYS C CB    1 
ATOM   10238 S  SG    . CYS C 2 32   ? 114.990 117.561 165.603 1.00 67.86  ? 47   CYS C SG    1 
ATOM   10239 N  N     . ARG C 2 33   ? 115.164 113.291 163.118 1.00 68.29  ? 48   ARG C N     1 
ATOM   10240 C  CA    . ARG C 2 33   ? 115.779 112.247 162.307 1.00 68.29  ? 48   ARG C CA    1 
ATOM   10241 C  C     . ARG C 2 33   ? 115.080 112.109 160.960 1.00 68.29  ? 48   ARG C C     1 
ATOM   10242 O  O     . ARG C 2 33   ? 115.736 112.013 159.916 1.00 68.29  ? 48   ARG C O     1 
ATOM   10243 C  CB    . ARG C 2 33   ? 115.756 110.921 163.070 1.00 68.29  ? 48   ARG C CB    1 
ATOM   10244 C  CG    . ARG C 2 33   ? 116.276 109.723 162.291 1.00 68.29  ? 48   ARG C CG    1 
ATOM   10245 C  CD    . ARG C 2 33   ? 117.759 109.850 161.987 1.00 68.29  ? 48   ARG C CD    1 
ATOM   10246 N  NE    . ARG C 2 33   ? 118.315 108.602 161.479 1.00 68.29  ? 48   ARG C NE    1 
ATOM   10247 C  CZ    . ARG C 2 33   ? 118.288 108.232 160.206 1.00 68.29  ? 48   ARG C CZ    1 
ATOM   10248 N  NH1   . ARG C 2 33   ? 117.734 108.993 159.277 1.00 68.29  ? 48   ARG C NH1   1 
ATOM   10249 N  NH2   . ARG C 2 33   ? 118.829 107.068 159.857 1.00 68.29  ? 48   ARG C NH2   1 
ATOM   10250 N  N     . ARG C 2 34   ? 113.745 112.100 160.962 1.00 72.22  ? 49   ARG C N     1 
ATOM   10251 C  CA    . ARG C 2 34   ? 113.012 111.875 159.720 1.00 72.22  ? 49   ARG C CA    1 
ATOM   10252 C  C     . ARG C 2 34   ? 113.102 113.079 158.788 1.00 72.22  ? 49   ARG C C     1 
ATOM   10253 O  O     . ARG C 2 34   ? 113.178 112.917 157.565 1.00 72.22  ? 49   ARG C O     1 
ATOM   10254 C  CB    . ARG C 2 34   ? 111.553 111.529 160.022 1.00 72.22  ? 49   ARG C CB    1 
ATOM   10255 C  CG    . ARG C 2 34   ? 110.786 112.605 160.767 1.00 72.22  ? 49   ARG C CG    1 
ATOM   10256 C  CD    . ARG C 2 34   ? 109.371 112.159 161.082 1.00 72.22  ? 49   ARG C CD    1 
ATOM   10257 N  NE    . ARG C 2 34   ? 108.640 111.783 159.878 1.00 72.22  ? 49   ARG C NE    1 
ATOM   10258 C  CZ    . ARG C 2 34   ? 107.356 111.451 159.855 1.00 72.22  ? 49   ARG C CZ    1 
ATOM   10259 N  NH1   . ARG C 2 34   ? 106.624 111.446 160.957 1.00 72.22  ? 49   ARG C NH1   1 
ATOM   10260 N  NH2   . ARG C 2 34   ? 106.793 111.117 158.697 1.00 72.22  ? 49   ARG C NH2   1 
ATOM   10261 N  N     . ARG C 2 35   ? 113.098 114.295 159.343 1.00 65.89  ? 50   ARG C N     1 
ATOM   10262 C  CA    . ARG C 2 35   ? 113.129 115.518 158.548 1.00 65.89  ? 50   ARG C CA    1 
ATOM   10263 C  C     . ARG C 2 35   ? 114.541 116.042 158.329 1.00 65.89  ? 50   ARG C C     1 
ATOM   10264 O  O     . ARG C 2 35   ? 114.724 117.248 158.110 1.00 65.89  ? 50   ARG C O     1 
ATOM   10265 C  CB    . ARG C 2 35   ? 112.255 116.592 159.196 1.00 65.89  ? 50   ARG C CB    1 
ATOM   10266 C  CG    . ARG C 2 35   ? 110.787 116.221 159.274 1.00 65.89  ? 50   ARG C CG    1 
ATOM   10267 C  CD    . ARG C 2 35   ? 110.275 115.727 157.934 1.00 65.89  ? 50   ARG C CD    1 
ATOM   10268 N  NE    . ARG C 2 35   ? 108.849 115.430 157.973 1.00 65.89  ? 50   ARG C NE    1 
ATOM   10269 C  CZ    . ARG C 2 35   ? 108.180 114.833 156.997 1.00 65.89  ? 50   ARG C CZ    1 
ATOM   10270 N  NH1   . ARG C 2 35   ? 108.783 114.433 155.889 1.00 65.89  ? 50   ARG C NH1   1 
ATOM   10271 N  NH2   . ARG C 2 35   ? 106.873 114.631 157.135 1.00 65.89  ? 50   ARG C NH2   1 
ATOM   10272 N  N     . HIS C 2 36   ? 115.544 115.166 158.393 1.00 59.38  ? 51   HIS C N     1 
ATOM   10273 C  CA    . HIS C 2 36   ? 116.926 115.500 158.049 1.00 59.38  ? 51   HIS C CA    1 
ATOM   10274 C  C     . HIS C 2 36   ? 117.503 116.595 158.940 1.00 59.38  ? 51   HIS C C     1 
ATOM   10275 O  O     . HIS C 2 36   ? 118.336 117.390 158.501 1.00 59.38  ? 51   HIS C O     1 
ATOM   10276 C  CB    . HIS C 2 36   ? 117.047 115.889 156.573 1.00 59.38  ? 51   HIS C CB    1 
ATOM   10277 C  CG    . HIS C 2 36   ? 116.864 114.738 155.634 1.00 59.38  ? 51   HIS C CG    1 
ATOM   10278 N  ND1   . HIS C 2 36   ? 116.751 114.899 154.271 1.00 59.38  ? 51   HIS C ND1   1 
ATOM   10279 C  CD2   . HIS C 2 36   ? 116.777 113.407 155.865 1.00 59.38  ? 51   HIS C CD2   1 
ATOM   10280 C  CE1   . HIS C 2 36   ? 116.601 113.717 153.701 1.00 59.38  ? 51   HIS C CE1   1 
ATOM   10281 N  NE2   . HIS C 2 36   ? 116.613 112.794 154.647 1.00 59.38  ? 51   HIS C NE2   1 
ATOM   10282 N  N     . PHE C 2 37   ? 117.067 116.649 160.196 1.00 53.40  ? 52   PHE C N     1 
ATOM   10283 C  CA    . PHE C 2 37   ? 117.739 117.452 161.210 1.00 53.40  ? 52   PHE C CA    1 
ATOM   10284 C  C     . PHE C 2 37   ? 118.718 116.634 162.038 1.00 53.40  ? 52   PHE C C     1 
ATOM   10285 O  O     . PHE C 2 37   ? 119.750 117.158 162.469 1.00 53.40  ? 52   PHE C O     1 
ATOM   10286 C  CB    . PHE C 2 37   ? 116.717 118.118 162.136 1.00 53.40  ? 52   PHE C CB    1 
ATOM   10287 C  CG    . PHE C 2 37   ? 116.141 119.392 161.589 1.00 53.40  ? 52   PHE C CG    1 
ATOM   10288 C  CD1   . PHE C 2 37   ? 116.939 120.509 161.422 1.00 53.40  ? 52   PHE C CD1   1 
ATOM   10289 C  CD2   . PHE C 2 37   ? 114.800 119.477 161.259 1.00 53.40  ? 52   PHE C CD2   1 
ATOM   10290 C  CE1   . PHE C 2 37   ? 116.416 121.681 160.924 1.00 53.40  ? 52   PHE C CE1   1 
ATOM   10291 C  CE2   . PHE C 2 37   ? 114.271 120.648 160.762 1.00 53.40  ? 52   PHE C CE2   1 
ATOM   10292 C  CZ    . PHE C 2 37   ? 115.080 121.751 160.595 1.00 53.40  ? 52   PHE C CZ    1 
ATOM   10293 N  N     . PHE C 2 38   ? 118.420 115.358 162.264 1.00 61.99  ? 53   PHE C N     1 
ATOM   10294 C  CA    . PHE C 2 38   ? 119.322 114.435 162.937 1.00 61.99  ? 53   PHE C CA    1 
ATOM   10295 C  C     . PHE C 2 38   ? 119.785 113.364 161.960 1.00 61.99  ? 53   PHE C C     1 
ATOM   10296 O  O     . PHE C 2 38   ? 118.977 112.788 161.225 1.00 61.99  ? 53   PHE C O     1 
ATOM   10297 C  CB    . PHE C 2 38   ? 118.648 113.778 164.144 1.00 61.99  ? 53   PHE C CB    1 
ATOM   10298 C  CG    . PHE C 2 38   ? 118.736 114.588 165.403 1.00 61.99  ? 53   PHE C CG    1 
ATOM   10299 C  CD1   . PHE C 2 38   ? 119.579 115.682 165.480 1.00 61.99  ? 53   PHE C CD1   1 
ATOM   10300 C  CD2   . PHE C 2 38   ? 117.983 114.248 166.513 1.00 61.99  ? 53   PHE C CD2   1 
ATOM   10301 C  CE1   . PHE C 2 38   ? 119.664 116.426 166.639 1.00 61.99  ? 53   PHE C CE1   1 
ATOM   10302 C  CE2   . PHE C 2 38   ? 118.063 114.988 167.674 1.00 61.99  ? 53   PHE C CE2   1 
ATOM   10303 C  CZ    . PHE C 2 38   ? 118.904 116.078 167.737 1.00 61.99  ? 53   PHE C CZ    1 
ATOM   10304 N  N     . SER C 2 39   ? 121.088 113.102 161.955 1.00 50.01  ? 54   SER C N     1 
ATOM   10305 C  CA    . SER C 2 39   ? 121.663 112.093 161.074 1.00 50.01  ? 54   SER C CA    1 
ATOM   10306 C  C     . SER C 2 39   ? 121.763 110.748 161.784 1.00 50.01  ? 54   SER C C     1 
ATOM   10307 O  O     . SER C 2 39   ? 121.556 110.658 162.994 1.00 50.01  ? 54   SER C O     1 
ATOM   10308 C  CB    . SER C 2 39   ? 123.043 112.535 160.581 1.00 50.01  ? 54   SER C CB    1 
ATOM   10309 O  OG    . SER C 2 39   ? 123.627 111.558 159.738 1.00 50.01  ? 54   SER C OG    1 
ATOM   10310 N  N     . ARG C 2 57   ? 125.122 113.400 163.110 1.00 46.96  ? 72   ARG C N     1 
ATOM   10311 C  CA    . ARG C 2 57   ? 124.339 114.184 164.055 1.00 46.96  ? 72   ARG C CA    1 
ATOM   10312 C  C     . ARG C 2 57   ? 123.432 115.172 163.345 1.00 46.96  ? 72   ARG C C     1 
ATOM   10313 O  O     . ARG C 2 57   ? 122.213 115.118 163.487 1.00 46.96  ? 72   ARG C O     1 
ATOM   10314 C  CB    . ARG C 2 57   ? 125.268 114.927 165.014 1.00 46.96  ? 72   ARG C CB    1 
ATOM   10315 C  CG    . ARG C 2 57   ? 126.329 115.778 164.330 1.00 46.96  ? 72   ARG C CG    1 
ATOM   10316 C  CD    . ARG C 2 57   ? 127.319 116.351 165.328 1.00 46.96  ? 72   ARG C CD    1 
ATOM   10317 N  NE    . ARG C 2 57   ? 126.653 116.897 166.505 1.00 46.96  ? 72   ARG C NE    1 
ATOM   10318 C  CZ    . ARG C 2 57   ? 127.286 117.497 167.506 1.00 46.96  ? 72   ARG C CZ    1 
ATOM   10319 N  NH1   . ARG C 2 57   ? 128.603 117.637 167.472 1.00 46.96  ? 72   ARG C NH1   1 
ATOM   10320 N  NH2   . ARG C 2 57   ? 126.601 117.962 168.541 1.00 46.96  ? 72   ARG C NH2   1 
ATOM   10321 N  N     . PHE C 2 58   ? 124.020 116.077 162.578 1.00 45.20  ? 73   PHE C N     1 
ATOM   10322 C  CA    . PHE C 2 58   ? 123.225 117.105 161.918 1.00 45.20  ? 73   PHE C CA    1 
ATOM   10323 C  C     . PHE C 2 58   ? 122.960 116.677 160.481 1.00 45.20  ? 73   PHE C C     1 
ATOM   10324 O  O     . PHE C 2 58   ? 123.894 116.541 159.684 1.00 45.20  ? 73   PHE C O     1 
ATOM   10325 C  CB    . PHE C 2 58   ? 123.940 118.454 161.960 1.00 45.20  ? 73   PHE C CB    1 
ATOM   10326 C  CG    . PHE C 2 58   ? 123.992 119.072 163.327 1.00 45.20  ? 73   PHE C CG    1 
ATOM   10327 C  CD1   . PHE C 2 58   ? 122.981 118.843 164.245 1.00 45.20  ? 73   PHE C CD1   1 
ATOM   10328 C  CD2   . PHE C 2 58   ? 125.052 119.882 163.691 1.00 45.20  ? 73   PHE C CD2   1 
ATOM   10329 C  CE1   . PHE C 2 58   ? 123.028 119.411 165.501 1.00 45.20  ? 73   PHE C CE1   1 
ATOM   10330 C  CE2   . PHE C 2 58   ? 125.105 120.452 164.944 1.00 45.20  ? 73   PHE C CE2   1 
ATOM   10331 C  CZ    . PHE C 2 58   ? 124.093 120.217 165.851 1.00 45.20  ? 73   PHE C CZ    1 
ATOM   10332 N  N     . GLY C 2 59   ? 121.684 116.464 160.151 1.00 49.43  ? 74   GLY C N     1 
ATOM   10333 C  CA    . GLY C 2 59   ? 121.297 116.210 158.794 1.00 49.43  ? 74   GLY C CA    1 
ATOM   10334 C  C     . GLY C 2 59   ? 121.426 117.456 157.936 1.00 49.43  ? 74   GLY C C     1 
ATOM   10335 O  O     . GLY C 2 59   ? 121.856 118.519 158.404 1.00 49.43  ? 74   GLY C O     1 
ATOM   10336 N  N     . PRO C 2 60   ? 121.063 117.331 156.656 1.00 46.98  ? 75   PRO C N     1 
ATOM   10337 C  CA    . PRO C 2 60   ? 121.177 118.494 155.757 1.00 46.98  ? 75   PRO C CA    1 
ATOM   10338 C  C     . PRO C 2 60   ? 120.434 119.718 156.261 1.00 46.98  ? 75   PRO C C     1 
ATOM   10339 O  O     . PRO C 2 60   ? 120.982 120.829 156.235 1.00 46.98  ? 75   PRO C O     1 
ATOM   10340 C  CB    . PRO C 2 60   ? 120.587 117.971 154.439 1.00 46.98  ? 75   PRO C CB    1 
ATOM   10341 C  CG    . PRO C 2 60   ? 120.770 116.495 154.505 1.00 46.98  ? 75   PRO C CG    1 
ATOM   10342 C  CD    . PRO C 2 60   ? 120.601 116.126 155.950 1.00 46.98  ? 75   PRO C CD    1 
ATOM   10343 N  N     . LEU C 2 61   ? 119.204 119.542 156.747 1.00 46.08  ? 76   LEU C N     1 
ATOM   10344 C  CA    . LEU C 2 61   ? 118.492 120.664 157.349 1.00 46.08  ? 76   LEU C CA    1 
ATOM   10345 C  C     . LEU C 2 61   ? 119.157 121.097 158.646 1.00 46.08  ? 76   LEU C C     1 
ATOM   10346 O  O     . LEU C 2 61   ? 119.203 122.292 158.956 1.00 46.08  ? 76   LEU C O     1 
ATOM   10347 C  CB    . LEU C 2 61   ? 117.027 120.299 157.585 1.00 46.08  ? 76   LEU C CB    1 
ATOM   10348 C  CG    . LEU C 2 61   ? 116.058 120.691 156.467 1.00 46.08  ? 76   LEU C CG    1 
ATOM   10349 C  CD1   . LEU C 2 61   ? 116.427 120.009 155.160 1.00 46.08  ? 76   LEU C CD1   1 
ATOM   10350 C  CD2   . LEU C 2 61   ? 114.624 120.374 156.853 1.00 46.08  ? 76   LEU C CD2   1 
ATOM   10351 N  N     . GLY C 2 62   ? 119.684 120.143 159.413 1.00 40.15  ? 77   GLY C N     1 
ATOM   10352 C  CA    . GLY C 2 62   ? 120.430 120.503 160.607 1.00 40.15  ? 77   GLY C CA    1 
ATOM   10353 C  C     . GLY C 2 62   ? 121.679 121.300 160.290 1.00 40.15  ? 77   GLY C C     1 
ATOM   10354 O  O     . GLY C 2 62   ? 122.001 122.270 160.980 1.00 40.15  ? 77   GLY C O     1 
ATOM   10355 N  N     . VAL C 2 63   ? 122.396 120.911 159.234 1.00 39.42  ? 78   VAL C N     1 
ATOM   10356 C  CA    . VAL C 2 63   ? 123.595 121.648 158.848 1.00 39.42  ? 78   VAL C CA    1 
ATOM   10357 C  C     . VAL C 2 63   ? 123.228 123.036 158.340 1.00 39.42  ? 78   VAL C C     1 
ATOM   10358 O  O     . VAL C 2 63   ? 123.936 124.012 158.606 1.00 39.42  ? 78   VAL C O     1 
ATOM   10359 C  CB    . VAL C 2 63   ? 124.401 120.853 157.805 1.00 39.42  ? 78   VAL C CB    1 
ATOM   10360 C  CG1   . VAL C 2 63   ? 125.585 121.669 157.312 1.00 39.42  ? 78   VAL C CG1   1 
ATOM   10361 C  CG2   . VAL C 2 63   ? 124.879 119.542 158.399 1.00 39.42  ? 78   VAL C CG2   1 
ATOM   10362 N  N     . GLU C 2 64   ? 122.114 123.152 157.612 1.00 38.75  ? 79   GLU C N     1 
ATOM   10363 C  CA    . GLU C 2 64   ? 121.671 124.467 157.157 1.00 38.75  ? 79   GLU C CA    1 
ATOM   10364 C  C     . GLU C 2 64   ? 121.271 125.359 158.329 1.00 38.75  ? 79   GLU C C     1 
ATOM   10365 O  O     . GLU C 2 64   ? 121.584 126.555 158.342 1.00 38.75  ? 79   GLU C O     1 
ATOM   10366 C  CB    . GLU C 2 64   ? 120.515 124.320 156.170 1.00 38.75  ? 79   GLU C CB    1 
ATOM   10367 C  CG    . GLU C 2 64   ? 120.938 123.856 154.782 1.00 38.75  ? 79   GLU C CG    1 
ATOM   10368 C  CD    . GLU C 2 64   ? 121.785 124.884 154.050 1.00 38.75  ? 79   GLU C CD    1 
ATOM   10369 O  OE1   . GLU C 2 64   ? 121.684 126.087 154.374 1.00 38.75  ? 79   GLU C OE1   1 
ATOM   10370 O  OE2   . GLU C 2 64   ? 122.555 124.487 153.150 1.00 38.75  ? 79   GLU C OE2   1 
ATOM   10371 N  N     . LEU C 2 65   ? 120.576 124.797 159.321 1.00 34.30  ? 80   LEU C N     1 
ATOM   10372 C  CA    . LEU C 2 65   ? 120.237 125.562 160.516 1.00 34.30  ? 80   LEU C CA    1 
ATOM   10373 C  C     . LEU C 2 65   ? 121.489 125.986 161.269 1.00 34.30  ? 80   LEU C C     1 
ATOM   10374 O  O     . LEU C 2 65   ? 121.564 127.107 161.782 1.00 34.30  ? 80   LEU C O     1 
ATOM   10375 C  CB    . LEU C 2 65   ? 119.320 124.746 161.424 1.00 34.30  ? 80   LEU C CB    1 
ATOM   10376 C  CG    . LEU C 2 65   ? 119.217 125.205 162.879 1.00 34.30  ? 80   LEU C CG    1 
ATOM   10377 C  CD1   . LEU C 2 65   ? 118.627 126.602 162.979 1.00 34.30  ? 80   LEU C CD1   1 
ATOM   10378 C  CD2   . LEU C 2 65   ? 118.398 124.221 163.685 1.00 34.30  ? 80   LEU C CD2   1 
ATOM   10379 N  N     . ARG C 2 66   ? 122.480 125.100 161.356 1.00 35.93  ? 81   ARG C N     1 
ATOM   10380 C  CA    . ARG C 2 66   ? 123.725 125.459 162.024 1.00 35.93  ? 81   ARG C CA    1 
ATOM   10381 C  C     . ARG C 2 66   ? 124.463 126.548 161.259 1.00 35.93  ? 81   ARG C C     1 
ATOM   10382 O  O     . ARG C 2 66   ? 125.082 127.428 161.865 1.00 35.93  ? 81   ARG C O     1 
ATOM   10383 C  CB    . ARG C 2 66   ? 124.605 124.223 162.187 1.00 35.93  ? 81   ARG C CB    1 
ATOM   10384 C  CG    . ARG C 2 66   ? 125.771 124.422 163.132 1.00 35.93  ? 81   ARG C CG    1 
ATOM   10385 C  CD    . ARG C 2 66   ? 126.652 123.190 163.166 1.00 35.93  ? 81   ARG C CD    1 
ATOM   10386 N  NE    . ARG C 2 66   ? 127.471 123.071 161.967 1.00 35.93  ? 81   ARG C NE    1 
ATOM   10387 C  CZ    . ARG C 2 66   ? 128.081 121.957 161.587 1.00 35.93  ? 81   ARG C CZ    1 
ATOM   10388 N  NH1   . ARG C 2 66   ? 127.959 120.835 162.276 1.00 35.93  ? 81   ARG C NH1   1 
ATOM   10389 N  NH2   . ARG C 2 66   ? 128.826 121.969 160.486 1.00 35.93  ? 81   ARG C NH2   1 
ATOM   10390 N  N     . LYS C 2 67   ? 124.409 126.506 159.927 1.00 32.30  ? 82   LYS C N     1 
ATOM   10391 C  CA    . LYS C 2 67   ? 125.011 127.564 159.125 1.00 32.30  ? 82   LYS C CA    1 
ATOM   10392 C  C     . LYS C 2 67   ? 124.300 128.892 159.347 1.00 32.30  ? 82   LYS C C     1 
ATOM   10393 O  O     . LYS C 2 67   ? 124.947 129.940 159.446 1.00 32.30  ? 82   LYS C O     1 
ATOM   10394 C  CB    . LYS C 2 67   ? 124.986 127.172 157.648 1.00 32.30  ? 82   LYS C CB    1 
ATOM   10395 C  CG    . LYS C 2 67   ? 125.769 128.096 156.732 1.00 32.30  ? 82   LYS C CG    1 
ATOM   10396 C  CD    . LYS C 2 67   ? 125.939 127.465 155.356 1.00 32.30  ? 82   LYS C CD    1 
ATOM   10397 C  CE    . LYS C 2 67   ? 126.685 128.382 154.402 1.00 32.30  ? 82   LYS C CE    1 
ATOM   10398 N  NZ    . LYS C 2 67   ? 125.883 129.583 154.045 1.00 32.30  ? 82   LYS C NZ    1 
ATOM   10399 N  N     . ASN C 2 68   ? 122.967 128.864 159.441 1.00 30.42  ? 83   ASN C N     1 
ATOM   10400 C  CA    . ASN C 2 68   ? 122.218 130.076 159.765 1.00 30.42  ? 83   ASN C CA    1 
ATOM   10401 C  C     . ASN C 2 68   ? 122.591 130.604 161.144 1.00 30.42  ? 83   ASN C C     1 
ATOM   10402 O  O     . ASN C 2 68   ? 122.743 131.814 161.333 1.00 30.42  ? 83   ASN C O     1 
ATOM   10403 C  CB    . ASN C 2 68   ? 120.715 129.810 159.694 1.00 30.42  ? 83   ASN C CB    1 
ATOM   10404 C  CG    . ASN C 2 68   ? 120.220 129.616 158.279 1.00 30.42  ? 83   ASN C CG    1 
ATOM   10405 O  OD1   . ASN C 2 68   ? 120.887 129.996 157.318 1.00 30.42  ? 83   ASN C OD1   1 
ATOM   10406 N  ND2   . ASN C 2 68   ? 119.037 129.031 158.144 1.00 30.42  ? 83   ASN C ND2   1 
ATOM   10407 N  N     . LEU C 2 69   ? 122.719 129.708 162.125 1.00 27.51  ? 84   LEU C N     1 
ATOM   10408 C  CA    . LEU C 2 69   ? 123.096 130.121 163.473 1.00 27.51  ? 84   LEU C CA    1 
ATOM   10409 C  C     . LEU C 2 69   ? 124.483 130.743 163.487 1.00 27.51  ? 84   LEU C C     1 
ATOM   10410 O  O     . LEU C 2 69   ? 124.711 131.767 164.144 1.00 27.51  ? 84   LEU C O     1 
ATOM   10411 C  CB    . LEU C 2 69   ? 123.040 128.920 164.415 1.00 27.51  ? 84   LEU C CB    1 
ATOM   10412 C  CG    . LEU C 2 69   ? 123.301 129.200 165.891 1.00 27.51  ? 84   LEU C CG    1 
ATOM   10413 C  CD1   . LEU C 2 69   ? 122.213 130.102 166.425 1.00 27.51  ? 84   LEU C CD1   1 
ATOM   10414 C  CD2   . LEU C 2 69   ? 123.366 127.906 166.682 1.00 27.51  ? 84   LEU C CD2   1 
ATOM   10415 N  N     . ALA C 2 70   ? 125.423 130.139 162.759 1.00 26.15  ? 85   ALA C N     1 
ATOM   10416 C  CA    . ALA C 2 70   ? 126.766 130.695 162.668 1.00 26.15  ? 85   ALA C CA    1 
ATOM   10417 C  C     . ALA C 2 70   ? 126.753 132.046 161.970 1.00 26.15  ? 85   ALA C C     1 
ATOM   10418 O  O     . ALA C 2 70   ? 127.503 132.950 162.346 1.00 26.15  ? 85   ALA C O     1 
ATOM   10419 C  CB    . ALA C 2 70   ? 127.688 129.720 161.937 1.00 26.15  ? 85   ALA C CB    1 
ATOM   10420 N  N     . SER C 2 71   ? 125.899 132.209 160.958 1.00 25.26  ? 86   SER C N     1 
ATOM   10421 C  CA    . SER C 2 71   ? 125.812 133.491 160.266 1.00 25.26  ? 86   SER C CA    1 
ATOM   10422 C  C     . SER C 2 71   ? 125.216 134.569 161.163 1.00 25.26  ? 86   SER C C     1 
ATOM   10423 O  O     . SER C 2 71   ? 125.667 135.719 161.140 1.00 25.26  ? 86   SER C O     1 
ATOM   10424 C  CB    . SER C 2 71   ? 124.988 133.342 158.989 1.00 25.26  ? 86   SER C CB    1 
ATOM   10425 O  OG    . SER C 2 71   ? 123.679 132.891 159.283 1.00 25.26  ? 86   SER C OG    1 
ATOM   10426 N  N     . GLN C 2 72   ? 124.192 134.224 161.946 1.00 26.19  ? 87   GLN C N     1 
ATOM   10427 C  CA    . GLN C 2 72   ? 123.629 135.185 162.891 1.00 26.19  ? 87   GLN C CA    1 
ATOM   10428 C  C     . GLN C 2 72   ? 124.656 135.581 163.940 1.00 26.19  ? 87   GLN C C     1 
ATOM   10429 O  O     . GLN C 2 72   ? 124.794 136.766 164.269 1.00 26.19  ? 87   GLN C O     1 
ATOM   10430 C  CB    . GLN C 2 72   ? 122.383 134.611 163.564 1.00 26.19  ? 87   GLN C CB    1 
ATOM   10431 C  CG    . GLN C 2 72   ? 121.267 134.219 162.615 1.00 26.19  ? 87   GLN C CG    1 
ATOM   10432 C  CD    . GLN C 2 72   ? 120.708 135.391 161.840 1.00 26.19  ? 87   GLN C CD    1 
ATOM   10433 O  OE1   . GLN C 2 72   ? 120.763 136.534 162.291 1.00 26.19  ? 87   GLN C OE1   1 
ATOM   10434 N  NE2   . GLN C 2 72   ? 120.167 135.112 160.661 1.00 26.19  ? 87   GLN C NE2   1 
ATOM   10435 N  N     . TRP C 2 73   ? 125.383 134.599 164.480 1.00 25.16  ? 88   TRP C N     1 
ATOM   10436 C  CA    . TRP C 2 73   ? 126.469 134.898 165.406 1.00 25.16  ? 88   TRP C CA    1 
ATOM   10437 C  C     . TRP C 2 73   ? 127.484 135.827 164.759 1.00 25.16  ? 88   TRP C C     1 
ATOM   10438 O  O     . TRP C 2 73   ? 127.901 136.826 165.354 1.00 25.16  ? 88   TRP C O     1 
ATOM   10439 C  CB    . TRP C 2 73   ? 127.137 133.597 165.858 1.00 25.16  ? 88   TRP C CB    1 
ATOM   10440 C  CG    . TRP C 2 73   ? 128.107 133.753 166.993 1.00 25.16  ? 88   TRP C CG    1 
ATOM   10441 C  CD1   . TRP C 2 73   ? 127.870 133.497 168.307 1.00 25.16  ? 88   TRP C CD1   1 
ATOM   10442 C  CD2   . TRP C 2 73   ? 129.470 134.188 166.909 1.00 25.16  ? 88   TRP C CD2   1 
ATOM   10443 N  NE1   . TRP C 2 73   ? 128.995 133.751 169.052 1.00 25.16  ? 88   TRP C NE1   1 
ATOM   10444 C  CE2   . TRP C 2 73   ? 129.992 134.177 168.215 1.00 25.16  ? 88   TRP C CE2   1 
ATOM   10445 C  CE3   . TRP C 2 73   ? 130.298 134.588 165.856 1.00 25.16  ? 88   TRP C CE3   1 
ATOM   10446 C  CZ2   . TRP C 2 73   ? 131.301 134.552 168.497 1.00 25.16  ? 88   TRP C CZ2   1 
ATOM   10447 C  CZ3   . TRP C 2 73   ? 131.595 134.961 166.138 1.00 25.16  ? 88   TRP C CZ3   1 
ATOM   10448 C  CH2   . TRP C 2 73   ? 132.085 134.940 167.447 1.00 25.16  ? 88   TRP C CH2   1 
ATOM   10449 N  N     . TRP C 2 74   ? 127.873 135.522 163.522 1.00 24.51  ? 89   TRP C N     1 
ATOM   10450 C  CA    . TRP C 2 74   ? 128.888 136.313 162.844 1.00 24.51  ? 89   TRP C CA    1 
ATOM   10451 C  C     . TRP C 2 74   ? 128.425 137.748 162.655 1.00 24.51  ? 89   TRP C C     1 
ATOM   10452 O  O     . TRP C 2 74   ? 129.159 138.691 162.961 1.00 24.51  ? 89   TRP C O     1 
ATOM   10453 C  CB    . TRP C 2 74   ? 129.230 135.674 161.500 1.00 24.51  ? 89   TRP C CB    1 
ATOM   10454 C  CG    . TRP C 2 74   ? 130.465 136.229 160.907 1.00 24.51  ? 89   TRP C CG    1 
ATOM   10455 C  CD1   . TRP C 2 74   ? 130.557 137.090 159.858 1.00 24.51  ? 89   TRP C CD1   1 
ATOM   10456 C  CD2   . TRP C 2 74   ? 131.803 135.977 161.342 1.00 24.51  ? 89   TRP C CD2   1 
ATOM   10457 N  NE1   . TRP C 2 74   ? 131.873 137.386 159.604 1.00 24.51  ? 89   TRP C NE1   1 
ATOM   10458 C  CE2   . TRP C 2 74   ? 132.658 136.714 160.504 1.00 24.51  ? 89   TRP C CE2   1 
ATOM   10459 C  CE3   . TRP C 2 74   ? 132.360 135.197 162.357 1.00 24.51  ? 89   TRP C CE3   1 
ATOM   10460 C  CZ2   . TRP C 2 74   ? 134.040 136.693 160.649 1.00 24.51  ? 89   TRP C CZ2   1 
ATOM   10461 C  CZ3   . TRP C 2 74   ? 133.729 135.177 162.499 1.00 24.51  ? 89   TRP C CZ3   1 
ATOM   10462 C  CH2   . TRP C 2 74   ? 134.556 135.920 161.650 1.00 24.51  ? 89   TRP C CH2   1 
ATOM   10463 N  N     . SER C 2 75   ? 127.194 137.933 162.176 1.00 26.28  ? 90   SER C N     1 
ATOM   10464 C  CA    . SER C 2 75   ? 126.683 139.282 161.967 1.00 26.28  ? 90   SER C CA    1 
ATOM   10465 C  C     . SER C 2 75   ? 126.609 140.043 163.282 1.00 26.28  ? 90   SER C C     1 
ATOM   10466 O  O     . SER C 2 75   ? 127.202 141.118 163.422 1.00 26.28  ? 90   SER C O     1 
ATOM   10467 C  CB    . SER C 2 75   ? 125.308 139.226 161.303 1.00 26.28  ? 90   SER C CB    1 
ATOM   10468 O  OG    . SER C 2 75   ? 124.358 138.619 162.160 1.00 26.28  ? 90   SER C OG    1 
ATOM   10469 N  N     . SER C 2 76   ? 125.941 139.460 164.281 1.00 26.42  ? 91   SER C N     1 
ATOM   10470 C  CA    . SER C 2 76   ? 125.695 140.152 165.538 1.00 26.42  ? 91   SER C CA    1 
ATOM   10471 C  C     . SER C 2 76   ? 126.961 140.389 166.349 1.00 26.42  ? 91   SER C C     1 
ATOM   10472 O  O     . SER C 2 76   ? 126.963 141.269 167.216 1.00 26.42  ? 91   SER C O     1 
ATOM   10473 C  CB    . SER C 2 76   ? 124.691 139.362 166.372 1.00 26.42  ? 91   SER C CB    1 
ATOM   10474 O  OG    . SER C 2 76   ? 124.477 139.981 167.625 1.00 26.42  ? 91   SER C OG    1 
ATOM   10475 N  N     . MET C 2 77   ? 128.034 139.638 166.100 1.00 27.01  ? 92   MET C N     1 
ATOM   10476 C  CA    . MET C 2 77   ? 129.245 139.787 166.891 1.00 27.01  ? 92   MET C CA    1 
ATOM   10477 C  C     . MET C 2 77   ? 130.404 140.419 166.138 1.00 27.01  ? 92   MET C C     1 
ATOM   10478 O  O     . MET C 2 77   ? 131.378 140.821 166.780 1.00 27.01  ? 92   MET C O     1 
ATOM   10479 C  CB    . MET C 2 77   ? 129.691 138.422 167.435 1.00 27.01  ? 92   MET C CB    1 
ATOM   10480 C  CG    . MET C 2 77   ? 128.637 137.709 168.262 1.00 27.01  ? 92   MET C CG    1 
ATOM   10481 S  SD    . MET C 2 77   ? 128.361 138.455 169.875 1.00 27.01  ? 92   MET C SD    1 
ATOM   10482 C  CE    . MET C 2 77   ? 129.978 138.243 170.601 1.00 27.01  ? 92   MET C CE    1 
ATOM   10483 N  N     . VAL C 2 78   ? 130.337 140.527 164.810 1.00 25.50  ? 93   VAL C N     1 
ATOM   10484 C  CA    . VAL C 2 78   ? 131.422 141.069 164.003 1.00 25.50  ? 93   VAL C CA    1 
ATOM   10485 C  C     . VAL C 2 78   ? 130.948 142.230 163.137 1.00 25.50  ? 93   VAL C C     1 
ATOM   10486 O  O     . VAL C 2 78   ? 131.618 143.262 163.043 1.00 25.50  ? 93   VAL C O     1 
ATOM   10487 C  CB    . VAL C 2 78   ? 132.073 139.972 163.132 1.00 25.50  ? 93   VAL C CB    1 
ATOM   10488 C  CG1   . VAL C 2 78   ? 133.231 140.544 162.332 1.00 25.50  ? 93   VAL C CG1   1 
ATOM   10489 C  CG2   . VAL C 2 78   ? 132.535 138.811 163.996 1.00 25.50  ? 93   VAL C CG2   1 
ATOM   10490 N  N     . VAL C 2 79   ? 129.801 142.071 162.479 1.00 25.80  ? 94   VAL C N     1 
ATOM   10491 C  CA    . VAL C 2 79   ? 129.333 143.097 161.553 1.00 25.80  ? 94   VAL C CA    1 
ATOM   10492 C  C     . VAL C 2 79   ? 128.671 144.240 162.309 1.00 25.80  ? 94   VAL C C     1 
ATOM   10493 O  O     . VAL C 2 79   ? 129.096 145.398 162.216 1.00 25.80  ? 94   VAL C O     1 
ATOM   10494 C  CB    . VAL C 2 79   ? 128.380 142.485 160.511 1.00 25.80  ? 94   VAL C CB    1 
ATOM   10495 C  CG1   . VAL C 2 79   ? 127.988 143.529 159.484 1.00 25.80  ? 94   VAL C CG1   1 
ATOM   10496 C  CG2   . VAL C 2 79   ? 129.031 141.288 159.840 1.00 25.80  ? 94   VAL C CG2   1 
ATOM   10497 N  N     . PHE C 2 80   ? 127.614 143.933 163.066 1.00 27.06  ? 95   PHE C N     1 
ATOM   10498 C  CA    . PHE C 2 80   ? 126.961 144.962 163.867 1.00 27.06  ? 95   PHE C CA    1 
ATOM   10499 C  C     . PHE C 2 80   ? 127.901 145.500 164.938 1.00 27.06  ? 95   PHE C C     1 
ATOM   10500 O  O     . PHE C 2 80   ? 127.946 146.711 165.185 1.00 27.06  ? 95   PHE C O     1 
ATOM   10501 C  CB    . PHE C 2 80   ? 125.684 144.408 164.500 1.00 27.06  ? 95   PHE C CB    1 
ATOM   10502 C  CG    . PHE C 2 80   ? 124.606 144.073 163.506 1.00 27.06  ? 95   PHE C CG    1 
ATOM   10503 C  CD1   . PHE C 2 80   ? 124.651 144.571 162.215 1.00 27.06  ? 95   PHE C CD1   1 
ATOM   10504 C  CD2   . PHE C 2 80   ? 123.541 143.265 163.867 1.00 27.06  ? 95   PHE C CD2   1 
ATOM   10505 C  CE1   . PHE C 2 80   ? 123.662 144.263 161.304 1.00 27.06  ? 95   PHE C CE1   1 
ATOM   10506 C  CE2   . PHE C 2 80   ? 122.549 142.955 162.959 1.00 27.06  ? 95   PHE C CE2   1 
ATOM   10507 C  CZ    . PHE C 2 80   ? 122.610 143.455 161.676 1.00 27.06  ? 95   PHE C CZ    1 
ATOM   10508 N  N     . ARG C 2 81   ? 128.662 144.618 165.577 1.00 30.06  ? 96   ARG C N     1 
ATOM   10509 C  CA    . ARG C 2 81   ? 129.595 145.027 166.615 1.00 30.06  ? 96   ARG C CA    1 
ATOM   10510 C  C     . ARG C 2 81   ? 130.825 145.680 166.002 1.00 30.06  ? 96   ARG C C     1 
ATOM   10511 O  O     . ARG C 2 81   ? 131.393 145.179 165.028 1.00 30.06  ? 96   ARG C O     1 
ATOM   10512 C  CB    . ARG C 2 81   ? 130.013 143.823 167.457 1.00 30.06  ? 96   ARG C CB    1 
ATOM   10513 C  CG    . ARG C 2 81   ? 130.217 144.138 168.922 1.00 30.06  ? 96   ARG C CG    1 
ATOM   10514 C  CD    . ARG C 2 81   ? 128.883 144.339 169.606 1.00 30.06  ? 96   ARG C CD    1 
ATOM   10515 N  NE    . ARG C 2 81   ? 128.025 143.172 169.446 1.00 30.06  ? 96   ARG C NE    1 
ATOM   10516 C  CZ    . ARG C 2 81   ? 126.757 143.119 169.828 1.00 30.06  ? 96   ARG C CZ    1 
ATOM   10517 N  NH1   . ARG C 2 81   ? 126.161 144.159 170.387 1.00 30.06  ? 96   ARG C NH1   1 
ATOM   10518 N  NH2   . ARG C 2 81   ? 126.070 141.996 169.643 1.00 30.06  ? 96   ARG C NH2   1 
ATOM   10519 N  N     . GLU C 2 82   ? 131.236 146.804 166.575 1.00 43.48  ? 97   GLU C N     1 
ATOM   10520 C  CA    . GLU C 2 82   ? 132.445 147.465 166.115 1.00 43.48  ? 97   GLU C CA    1 
ATOM   10521 C  C     . GLU C 2 82   ? 133.680 146.708 166.599 1.00 43.48  ? 97   GLU C C     1 
ATOM   10522 O  O     . GLU C 2 82   ? 133.611 145.849 167.482 1.00 43.48  ? 97   GLU C O     1 
ATOM   10523 C  CB    . GLU C 2 82   ? 132.486 148.914 166.600 1.00 43.48  ? 97   GLU C CB    1 
ATOM   10524 C  CG    . GLU C 2 82   ? 131.470 149.831 165.934 1.00 43.48  ? 97   GLU C CG    1 
ATOM   10525 C  CD    . GLU C 2 82   ? 131.878 150.236 164.528 1.00 43.48  ? 97   GLU C CD    1 
ATOM   10526 O  OE1   . GLU C 2 82   ? 133.072 150.099 164.192 1.00 43.48  ? 97   GLU C OE1   1 
ATOM   10527 O  OE2   . GLU C 2 82   ? 131.004 150.691 163.760 1.00 43.48  ? 97   GLU C OE2   1 
ATOM   10528 N  N     . GLN C 2 83   ? 134.822 147.048 165.994 1.00 51.24  ? 98   GLN C N     1 
ATOM   10529 C  CA    . GLN C 2 83   ? 136.157 146.574 166.362 1.00 51.24  ? 98   GLN C CA    1 
ATOM   10530 C  C     . GLN C 2 83   ? 136.218 145.090 166.719 1.00 51.24  ? 98   GLN C C     1 
ATOM   10531 O  O     . GLN C 2 83   ? 136.888 144.704 167.682 1.00 51.24  ? 98   GLN C O     1 
ATOM   10532 C  CB    . GLN C 2 83   ? 136.723 147.424 167.511 1.00 51.24  ? 98   GLN C CB    1 
ATOM   10533 C  CG    . GLN C 2 83   ? 135.902 147.455 168.794 1.00 51.24  ? 98   GLN C CG    1 
ATOM   10534 C  CD    . GLN C 2 83   ? 136.146 148.705 169.612 1.00 51.24  ? 98   GLN C CD    1 
ATOM   10535 O  OE1   . GLN C 2 83   ? 137.016 149.512 169.289 1.00 51.24  ? 98   GLN C OE1   1 
ATOM   10536 N  NE2   . GLN C 2 83   ? 135.371 148.875 170.676 1.00 51.24  ? 98   GLN C NE2   1 
ATOM   10537 N  N     . VAL C 2 84   ? 135.536 144.250 165.942 1.00 37.86  ? 99   VAL C N     1 
ATOM   10538 C  CA    . VAL C 2 84   ? 135.645 142.799 166.051 1.00 37.86  ? 99   VAL C CA    1 
ATOM   10539 C  C     . VAL C 2 84   ? 135.929 142.252 164.660 1.00 37.86  ? 99   VAL C C     1 
ATOM   10540 O  O     . VAL C 2 84   ? 135.249 142.621 163.696 1.00 37.86  ? 99   VAL C O     1 
ATOM   10541 C  CB    . VAL C 2 84   ? 134.373 142.161 166.638 1.00 37.86  ? 99   VAL C CB    1 
ATOM   10542 C  CG1   . VAL C 2 84   ? 134.515 140.654 166.668 1.00 37.86  ? 99   VAL C CG1   1 
ATOM   10543 C  CG2   . VAL C 2 84   ? 134.110 142.694 168.032 1.00 37.86  ? 99   VAL C CG2   1 
ATOM   10544 N  N     . PHE C 2 85   ? 136.933 141.384 164.552 1.00 36.06  ? 100  PHE C N     1 
ATOM   10545 C  CA    . PHE C 2 85   ? 137.458 140.966 163.260 1.00 36.06  ? 100  PHE C CA    1 
ATOM   10546 C  C     . PHE C 2 85   ? 137.476 139.449 163.150 1.00 36.06  ? 100  PHE C C     1 
ATOM   10547 O  O     . PHE C 2 85   ? 137.166 138.723 164.098 1.00 36.06  ? 100  PHE C O     1 
ATOM   10548 C  CB    . PHE C 2 85   ? 138.867 141.522 163.030 1.00 36.06  ? 100  PHE C CB    1 
ATOM   10549 C  CG    . PHE C 2 85   ? 138.942 143.014 163.108 1.00 36.06  ? 100  PHE C CG    1 
ATOM   10550 C  CD1   . PHE C 2 85   ? 139.090 143.648 164.328 1.00 36.06  ? 100  PHE C CD1   1 
ATOM   10551 C  CD2   . PHE C 2 85   ? 138.862 143.785 161.963 1.00 36.06  ? 100  PHE C CD2   1 
ATOM   10552 C  CE1   . PHE C 2 85   ? 139.155 145.019 164.406 1.00 36.06  ? 100  PHE C CE1   1 
ATOM   10553 C  CE2   . PHE C 2 85   ? 138.931 145.161 162.034 1.00 36.06  ? 100  PHE C CE2   1 
ATOM   10554 C  CZ    . PHE C 2 85   ? 139.079 145.779 163.257 1.00 36.06  ? 100  PHE C CZ    1 
ATOM   10555 N  N     . ALA C 2 86   ? 137.852 138.981 161.965 1.00 32.01  ? 101  ALA C N     1 
ATOM   10556 C  CA    . ALA C 2 86   ? 137.919 137.562 161.652 1.00 32.01  ? 101  ALA C CA    1 
ATOM   10557 C  C     . ALA C 2 86   ? 139.344 137.054 161.816 1.00 32.01  ? 101  ALA C C     1 
ATOM   10558 O  O     . ALA C 2 86   ? 140.307 137.757 161.496 1.00 32.01  ? 101  ALA C O     1 
ATOM   10559 C  CB    . ALA C 2 86   ? 137.437 137.297 160.226 1.00 32.01  ? 101  ALA C CB    1 
ATOM   10560 N  N     . VAL C 2 87   ? 139.470 135.828 162.312 1.00 32.69  ? 102  VAL C N     1 
ATOM   10561 C  CA    . VAL C 2 87   ? 140.760 135.190 162.533 1.00 32.69  ? 102  VAL C CA    1 
ATOM   10562 C  C     . VAL C 2 87   ? 140.736 133.819 161.877 1.00 32.69  ? 102  VAL C C     1 
ATOM   10563 O  O     . VAL C 2 87   ? 139.792 133.048 162.077 1.00 32.69  ? 102  VAL C O     1 
ATOM   10564 C  CB    . VAL C 2 87   ? 141.083 135.071 164.034 1.00 32.69  ? 102  VAL C CB    1 
ATOM   10565 C  CG1   . VAL C 2 87   ? 142.086 133.962 164.282 1.00 32.69  ? 102  VAL C CG1   1 
ATOM   10566 C  CG2   . VAL C 2 87   ? 141.615 136.389 164.556 1.00 32.69  ? 102  VAL C CG2   1 
ATOM   10567 N  N     . ASP C 2 88   ? 141.764 133.521 161.086 1.00 34.94  ? 103  ASP C N     1 
ATOM   10568 C  CA    . ASP C 2 88   ? 141.944 132.204 160.494 1.00 34.94  ? 103  ASP C CA    1 
ATOM   10569 C  C     . ASP C 2 88   ? 143.235 131.602 161.025 1.00 34.94  ? 103  ASP C C     1 
ATOM   10570 O  O     . ASP C 2 88   ? 144.296 132.229 160.946 1.00 34.94  ? 103  ASP C O     1 
ATOM   10571 C  CB    . ASP C 2 88   ? 141.985 132.279 158.967 1.00 34.94  ? 103  ASP C CB    1 
ATOM   10572 C  CG    . ASP C 2 88   ? 141.896 130.912 158.313 1.00 34.94  ? 103  ASP C CG    1 
ATOM   10573 O  OD1   . ASP C 2 88   ? 141.657 129.919 159.032 1.00 34.94  ? 103  ASP C OD1   1 
ATOM   10574 O  OD2   . ASP C 2 88   ? 142.064 130.830 157.077 1.00 34.94  ? 103  ASP C OD2   1 
ATOM   10575 N  N     . SER C 2 89   ? 143.145 130.386 161.556 1.00 38.04  ? 104  SER C N     1 
ATOM   10576 C  CA    . SER C 2 89   ? 144.309 129.696 162.086 1.00 38.04  ? 104  SER C CA    1 
ATOM   10577 C  C     . SER C 2 89   ? 144.163 128.204 161.837 1.00 38.04  ? 104  SER C C     1 
ATOM   10578 O  O     . SER C 2 89   ? 143.051 127.676 161.751 1.00 38.04  ? 104  SER C O     1 
ATOM   10579 C  CB    . SER C 2 89   ? 144.500 129.976 163.580 1.00 38.04  ? 104  SER C CB    1 
ATOM   10580 O  OG    . SER C 2 89   ? 144.820 131.340 163.794 1.00 38.04  ? 104  SER C OG    1 
ATOM   10581 N  N     . LEU C 2 90   ? 145.305 127.532 161.721 1.00 38.21  ? 105  LEU C N     1 
ATOM   10582 C  CA    . LEU C 2 90   ? 145.324 126.132 161.334 1.00 38.21  ? 105  LEU C CA    1 
ATOM   10583 C  C     . LEU C 2 90   ? 144.799 125.247 162.459 1.00 38.21  ? 105  LEU C C     1 
ATOM   10584 O  O     . LEU C 2 90   ? 144.799 125.615 163.636 1.00 38.21  ? 105  LEU C O     1 
ATOM   10585 C  CB    . LEU C 2 90   ? 146.739 125.711 160.945 1.00 38.21  ? 105  LEU C CB    1 
ATOM   10586 C  CG    . LEU C 2 90   ? 147.362 126.542 159.823 1.00 38.21  ? 105  LEU C CG    1 
ATOM   10587 C  CD1   . LEU C 2 90   ? 148.747 126.028 159.482 1.00 38.21  ? 105  LEU C CD1   1 
ATOM   10588 C  CD2   . LEU C 2 90   ? 146.467 126.536 158.595 1.00 38.21  ? 105  LEU C CD2   1 
ATOM   10589 N  N     . HIS C 2 91   ? 144.345 124.055 162.073 1.00 37.42  ? 106  HIS C N     1 
ATOM   10590 C  CA    . HIS C 2 91   ? 143.778 123.114 163.027 1.00 37.42  ? 106  HIS C CA    1 
ATOM   10591 C  C     . HIS C 2 91   ? 144.832 122.443 163.896 1.00 37.42  ? 106  HIS C C     1 
ATOM   10592 O  O     . HIS C 2 91   ? 144.504 121.980 164.992 1.00 37.42  ? 106  HIS C O     1 
ATOM   10593 C  CB    . HIS C 2 91   ? 142.968 122.042 162.293 1.00 37.42  ? 106  HIS C CB    1 
ATOM   10594 C  CG    . HIS C 2 91   ? 141.842 122.585 161.472 1.00 37.42  ? 106  HIS C CG    1 
ATOM   10595 N  ND1   . HIS C 2 91   ? 140.594 122.001 161.449 1.00 37.42  ? 106  HIS C ND1   1 
ATOM   10596 C  CD2   . HIS C 2 91   ? 141.775 123.649 160.638 1.00 37.42  ? 106  HIS C CD2   1 
ATOM   10597 C  CE1   . HIS C 2 91   ? 139.805 122.685 160.640 1.00 37.42  ? 106  HIS C CE1   1 
ATOM   10598 N  NE2   . HIS C 2 91   ? 140.497 123.691 160.135 1.00 37.42  ? 106  HIS C NE2   1 
ATOM   10599 N  N     . GLN C 2 92   ? 146.077 122.376 163.442 1.00 44.06  ? 107  GLN C N     1 
ATOM   10600 C  CA    . GLN C 2 92   ? 147.131 121.718 164.197 1.00 44.06  ? 107  GLN C CA    1 
ATOM   10601 C  C     . GLN C 2 92   ? 147.971 122.749 164.941 1.00 44.06  ? 107  GLN C C     1 
ATOM   10602 O  O     . GLN C 2 92   ? 148.132 123.889 164.497 1.00 44.06  ? 107  GLN C O     1 
ATOM   10603 C  CB    . GLN C 2 92   ? 148.021 120.868 163.286 1.00 44.06  ? 107  GLN C CB    1 
ATOM   10604 C  CG    . GLN C 2 92   ? 149.242 121.581 162.733 1.00 44.06  ? 107  GLN C CG    1 
ATOM   10605 C  CD    . GLN C 2 92   ? 148.897 122.569 161.644 1.00 44.06  ? 107  GLN C CD    1 
ATOM   10606 O  OE1   . GLN C 2 92   ? 147.863 122.452 160.989 1.00 44.06  ? 107  GLN C OE1   1 
ATOM   10607 N  NE2   . GLN C 2 92   ? 149.764 123.553 161.444 1.00 44.06  ? 107  GLN C NE2   1 
ATOM   10608 N  N     . GLU C 2 93   ? 148.491 122.338 166.083 1.00 49.68  ? 108  GLU C N     1 
ATOM   10609 C  CA    . GLU C 2 93   ? 149.277 123.198 166.950 1.00 49.68  ? 108  GLU C CA    1 
ATOM   10610 C  C     . GLU C 2 93   ? 150.759 122.883 166.822 1.00 49.68  ? 108  GLU C C     1 
ATOM   10611 O  O     . GLU C 2 93   ? 151.138 121.780 166.417 1.00 49.68  ? 108  GLU C O     1 
ATOM   10612 C  CB    . GLU C 2 93   ? 148.824 123.032 168.403 1.00 49.68  ? 108  GLU C CB    1 
ATOM   10613 C  CG    . GLU C 2 93   ? 147.374 123.414 168.627 1.00 49.68  ? 108  GLU C CG    1 
ATOM   10614 C  CD    . GLU C 2 93   ? 147.063 123.683 170.081 1.00 49.68  ? 108  GLU C CD    1 
ATOM   10615 O  OE1   . GLU C 2 93   ? 147.975 123.534 170.919 1.00 49.68  ? 108  GLU C OE1   1 
ATOM   10616 O  OE2   . GLU C 2 93   ? 145.909 124.049 170.385 1.00 49.68  ? 108  GLU C OE2   1 
ATOM   10617 N  N     . PRO C 2 94   ? 151.631 123.844 167.145 1.00 52.66  ? 109  PRO C N     1 
ATOM   10618 C  CA    . PRO C 2 94   ? 153.076 123.606 166.985 1.00 52.66  ? 109  PRO C CA    1 
ATOM   10619 C  C     . PRO C 2 94   ? 153.598 122.424 167.781 1.00 52.66  ? 109  PRO C C     1 
ATOM   10620 O  O     . PRO C 2 94   ? 154.563 121.780 167.350 1.00 52.66  ? 109  PRO C O     1 
ATOM   10621 C  CB    . PRO C 2 94   ? 153.698 124.925 167.465 1.00 52.66  ? 109  PRO C CB    1 
ATOM   10622 C  CG    . PRO C 2 94   ? 152.635 125.942 167.240 1.00 52.66  ? 109  PRO C CG    1 
ATOM   10623 C  CD    . PRO C 2 94   ? 151.341 125.239 167.522 1.00 52.66  ? 109  PRO C CD    1 
ATOM   10624 N  N     . GLY C 2 95   ? 153.001 122.120 168.931 1.00 58.10  ? 110  GLY C N     1 
ATOM   10625 C  CA    . GLY C 2 95   ? 153.415 120.967 169.705 1.00 58.10  ? 110  GLY C CA    1 
ATOM   10626 C  C     . GLY C 2 95   ? 154.306 121.310 170.880 1.00 58.10  ? 110  GLY C C     1 
ATOM   10627 O  O     . GLY C 2 95   ? 155.434 121.777 170.700 1.00 58.10  ? 110  GLY C O     1 
ATOM   10628 N  N     . SER C 2 96   ? 153.808 121.079 172.089 1.00 65.82  ? 111  SER C N     1 
ATOM   10629 C  CA    . SER C 2 96   ? 154.549 121.348 173.311 1.00 65.82  ? 111  SER C CA    1 
ATOM   10630 C  C     . SER C 2 96   ? 155.264 120.089 173.788 1.00 65.82  ? 111  SER C C     1 
ATOM   10631 O  O     . SER C 2 96   ? 155.045 118.988 173.278 1.00 65.82  ? 111  SER C O     1 
ATOM   10632 C  CB    . SER C 2 96   ? 153.615 121.867 174.408 1.00 65.82  ? 111  SER C CB    1 
ATOM   10633 O  OG    . SER C 2 96   ? 152.956 123.053 174.000 1.00 65.82  ? 111  SER C OG    1 
ATOM   10634 N  N     . SER C 2 97   ? 156.131 120.269 174.780 1.00 75.59  ? 112  SER C N     1 
ATOM   10635 C  CA    . SER C 2 97   ? 156.879 119.168 175.369 1.00 75.59  ? 112  SER C CA    1 
ATOM   10636 C  C     . SER C 2 97   ? 156.186 118.557 176.579 1.00 75.59  ? 112  SER C C     1 
ATOM   10637 O  O     . SER C 2 97   ? 156.715 117.605 177.162 1.00 75.59  ? 112  SER C O     1 
ATOM   10638 C  CB    . SER C 2 97   ? 158.282 119.639 175.766 1.00 75.59  ? 112  SER C CB    1 
ATOM   10639 O  OG    . SER C 2 97   ? 158.215 120.678 176.726 1.00 75.59  ? 112  SER C OG    1 
ATOM   10640 N  N     . GLN C 2 98   ? 155.027 119.075 176.970 1.00 83.78  ? 113  GLN C N     1 
ATOM   10641 C  CA    . GLN C 2 98   ? 154.349 118.600 178.170 1.00 83.78  ? 113  GLN C CA    1 
ATOM   10642 C  C     . GLN C 2 98   ? 153.473 117.398 177.840 1.00 83.78  ? 113  GLN C C     1 
ATOM   10643 O  O     . GLN C 2 98   ? 152.527 117.531 177.056 1.00 83.78  ? 113  GLN C O     1 
ATOM   10644 C  CB    . GLN C 2 98   ? 153.505 119.714 178.773 1.00 83.78  ? 113  GLN C CB    1 
ATOM   10645 C  CG    . GLN C 2 98   ? 154.271 121.002 179.015 1.00 83.78  ? 113  GLN C CG    1 
ATOM   10646 C  CD    . GLN C 2 98   ? 153.376 122.135 179.473 1.00 83.78  ? 113  GLN C CD    1 
ATOM   10647 O  OE1   . GLN C 2 98   ? 152.193 121.934 179.748 1.00 83.78  ? 113  GLN C OE1   1 
ATOM   10648 N  NE2   . GLN C 2 98   ? 153.936 123.336 179.553 1.00 83.78  ? 113  GLN C NE2   1 
ATOM   10649 N  N     . PRO C 2 99   ? 153.743 116.218 178.409 1.00 82.50  ? 114  PRO C N     1 
ATOM   10650 C  CA    . PRO C 2 99   ? 152.877 115.057 178.149 1.00 82.50  ? 114  PRO C CA    1 
ATOM   10651 C  C     . PRO C 2 99   ? 151.511 115.151 178.807 1.00 82.50  ? 114  PRO C C     1 
ATOM   10652 O  O     . PRO C 2 99   ? 150.638 114.333 178.490 1.00 82.50  ? 114  PRO C O     1 
ATOM   10653 C  CB    . PRO C 2 99   ? 153.681 113.879 178.723 1.00 82.50  ? 114  PRO C CB    1 
ATOM   10654 C  CG    . PRO C 2 99   ? 155.080 114.399 178.902 1.00 82.50  ? 114  PRO C CG    1 
ATOM   10655 C  CD    . PRO C 2 99   ? 154.926 115.854 179.203 1.00 82.50  ? 114  PRO C CD    1 
ATOM   10656 N  N     . ARG C 2 100  ? 151.298 116.112 179.711 1.00 78.04  ? 115  ARG C N     1 
ATOM   10657 C  CA    . ARG C 2 100  ? 150.025 116.220 180.413 1.00 78.04  ? 115  ARG C CA    1 
ATOM   10658 C  C     . ARG C 2 100  ? 148.866 116.542 179.479 1.00 78.04  ? 115  ARG C C     1 
ATOM   10659 O  O     . ARG C 2 100  ? 147.713 116.260 179.825 1.00 78.04  ? 115  ARG C O     1 
ATOM   10660 C  CB    . ARG C 2 100  ? 150.118 117.283 181.508 1.00 78.04  ? 115  ARG C CB    1 
ATOM   10661 N  N     . ASP C 2 101  ? 149.139 117.127 178.317 1.00 75.42  ? 116  ASP C N     1 
ATOM   10662 C  CA    . ASP C 2 101  ? 148.080 117.436 177.367 1.00 75.42  ? 116  ASP C CA    1 
ATOM   10663 C  C     . ASP C 2 101  ? 147.484 116.154 176.797 1.00 75.42  ? 116  ASP C C     1 
ATOM   10664 O  O     . ASP C 2 101  ? 148.200 115.192 176.506 1.00 75.42  ? 116  ASP C O     1 
ATOM   10665 C  CB    . ASP C 2 101  ? 148.619 118.314 176.240 1.00 75.42  ? 116  ASP C CB    1 
ATOM   10666 C  CG    . ASP C 2 101  ? 149.374 119.523 176.756 1.00 75.42  ? 116  ASP C CG    1 
ATOM   10667 O  OD1   . ASP C 2 101  ? 149.613 119.598 177.979 1.00 75.42  ? 116  ASP C OD1   1 
ATOM   10668 O  OD2   . ASP C 2 101  ? 149.726 120.399 175.939 1.00 75.42  ? 116  ASP C OD2   1 
ATOM   10669 N  N     . SER C 2 102  ? 146.163 116.145 176.642 1.00 61.20  ? 117  SER C N     1 
ATOM   10670 C  CA    . SER C 2 102  ? 145.447 114.994 176.109 1.00 61.20  ? 117  SER C CA    1 
ATOM   10671 C  C     . SER C 2 102  ? 145.170 115.104 174.616 1.00 61.20  ? 117  SER C C     1 
ATOM   10672 O  O     . SER C 2 102  ? 144.495 114.232 174.060 1.00 61.20  ? 117  SER C O     1 
ATOM   10673 C  CB    . SER C 2 102  ? 144.127 114.799 176.861 1.00 61.20  ? 117  SER C CB    1 
ATOM   10674 O  OG    . SER C 2 102  ? 143.396 113.707 176.332 1.00 61.20  ? 117  SER C OG    1 
ATOM   10675 N  N     . ALA C 2 103  ? 145.664 116.149 173.958 1.00 56.80  ? 118  ALA C N     1 
ATOM   10676 C  CA    . ALA C 2 103  ? 145.391 116.336 172.541 1.00 56.80  ? 118  ALA C CA    1 
ATOM   10677 C  C     . ALA C 2 103  ? 146.105 115.281 171.707 1.00 56.80  ? 118  ALA C C     1 
ATOM   10678 O  O     . ALA C 2 103  ? 147.260 114.934 171.968 1.00 56.80  ? 118  ALA C O     1 
ATOM   10679 C  CB    . ALA C 2 103  ? 145.820 117.734 172.098 1.00 56.80  ? 118  ALA C CB    1 
ATOM   10680 N  N     . PHE C 2 104  ? 145.407 114.771 170.696 1.00 60.30  ? 119  PHE C N     1 
ATOM   10681 C  CA    . PHE C 2 104  ? 145.985 113.781 169.801 1.00 60.30  ? 119  PHE C CA    1 
ATOM   10682 C  C     . PHE C 2 104  ? 147.128 114.385 168.995 1.00 60.30  ? 119  PHE C C     1 
ATOM   10683 O  O     . PHE C 2 104  ? 147.124 115.572 168.663 1.00 60.30  ? 119  PHE C O     1 
ATOM   10684 C  CB    . PHE C 2 104  ? 144.918 113.226 168.861 1.00 60.30  ? 119  PHE C CB    1 
ATOM   10685 C  CG    . PHE C 2 104  ? 143.903 112.370 169.549 1.00 60.30  ? 119  PHE C CG    1 
ATOM   10686 C  CD1   . PHE C 2 104  ? 142.855 112.941 170.249 1.00 60.30  ? 119  PHE C CD1   1 
ATOM   10687 C  CD2   . PHE C 2 104  ? 144.000 110.991 169.502 1.00 60.30  ? 119  PHE C CD2   1 
ATOM   10688 C  CE1   . PHE C 2 104  ? 141.921 112.152 170.888 1.00 60.30  ? 119  PHE C CE1   1 
ATOM   10689 C  CE2   . PHE C 2 104  ? 143.069 110.196 170.137 1.00 60.30  ? 119  PHE C CE2   1 
ATOM   10690 C  CZ    . PHE C 2 104  ? 142.028 110.777 170.833 1.00 60.30  ? 119  PHE C CZ    1 
ATOM   10691 N  N     . ARG C 2 105  ? 148.109 113.550 168.677 1.00 58.62  ? 120  ARG C N     1 
ATOM   10692 C  CA    . ARG C 2 105  ? 149.316 113.983 167.992 1.00 58.62  ? 120  ARG C CA    1 
ATOM   10693 C  C     . ARG C 2 105  ? 149.272 113.596 166.519 1.00 58.62  ? 120  ARG C C     1 
ATOM   10694 O  O     . ARG C 2 105  ? 148.597 112.645 166.119 1.00 58.62  ? 120  ARG C O     1 
ATOM   10695 C  CB    . ARG C 2 105  ? 150.555 113.376 168.652 1.00 58.62  ? 120  ARG C CB    1 
ATOM   10696 C  CG    . ARG C 2 105  ? 150.694 113.695 170.127 1.00 58.62  ? 120  ARG C CG    1 
ATOM   10697 C  CD    . ARG C 2 105  ? 151.175 115.116 170.345 1.00 58.62  ? 120  ARG C CD    1 
ATOM   10698 N  NE    . ARG C 2 105  ? 151.273 115.434 171.764 1.00 58.62  ? 120  ARG C NE    1 
ATOM   10699 C  CZ    . ARG C 2 105  ? 151.811 116.544 172.249 1.00 58.62  ? 120  ARG C CZ    1 
ATOM   10700 N  NH1   . ARG C 2 105  ? 152.325 117.468 171.454 1.00 58.62  ? 120  ARG C NH1   1 
ATOM   10701 N  NH2   . ARG C 2 105  ? 151.836 116.731 173.566 1.00 58.62  ? 120  ARG C NH2   1 
ATOM   10702 N  N     . LEU C 2 106  ? 150.010 114.354 165.710 1.00 55.52  ? 121  LEU C N     1 
ATOM   10703 C  CA    . LEU C 2 106  ? 150.126 114.106 164.277 1.00 55.52  ? 121  LEU C CA    1 
ATOM   10704 C  C     . LEU C 2 106  ? 151.475 113.451 164.006 1.00 55.52  ? 121  LEU C C     1 
ATOM   10705 O  O     . LEU C 2 106  ? 152.524 114.075 164.197 1.00 55.52  ? 121  LEU C O     1 
ATOM   10706 C  CB    . LEU C 2 106  ? 149.985 115.403 163.483 1.00 55.52  ? 121  LEU C CB    1 
ATOM   10707 C  CG    . LEU C 2 106  ? 148.668 116.168 163.596 1.00 55.52  ? 121  LEU C CG    1 
ATOM   10708 C  CD1   . LEU C 2 106  ? 148.680 117.373 162.674 1.00 55.52  ? 121  LEU C CD1   1 
ATOM   10709 C  CD2   . LEU C 2 106  ? 147.499 115.263 163.276 1.00 55.52  ? 121  LEU C CD2   1 
ATOM   10710 N  N     . VAL C 2 107  ? 151.448 112.201 163.554 1.00 58.02  ? 122  VAL C N     1 
ATOM   10711 C  CA    . VAL C 2 107  ? 152.655 111.441 163.251 1.00 58.02  ? 122  VAL C CA    1 
ATOM   10712 C  C     . VAL C 2 107  ? 152.610 111.023 161.788 1.00 58.02  ? 122  VAL C C     1 
ATOM   10713 O  O     . VAL C 2 107  ? 151.605 110.474 161.322 1.00 58.02  ? 122  VAL C O     1 
ATOM   10714 C  CB    . VAL C 2 107  ? 152.806 110.219 164.178 1.00 58.02  ? 122  VAL C CB    1 
ATOM   10715 C  CG1   . VAL C 2 107  ? 153.128 110.674 165.588 1.00 58.02  ? 122  VAL C CG1   1 
ATOM   10716 C  CG2   . VAL C 2 107  ? 151.542 109.378 164.177 1.00 58.02  ? 122  VAL C CG2   1 
ATOM   10717 N  N     . SER C 2 108  ? 153.685 111.304 161.065 1.00 57.40  ? 123  SER C N     1 
ATOM   10718 C  CA    . SER C 2 108  ? 153.755 110.928 159.659 1.00 57.40  ? 123  SER C CA    1 
ATOM   10719 C  C     . SER C 2 108  ? 154.083 109.444 159.537 1.00 57.40  ? 123  SER C C     1 
ATOM   10720 O  O     . SER C 2 108  ? 155.075 108.987 160.114 1.00 57.40  ? 123  SER C O     1 
ATOM   10721 C  CB    . SER C 2 108  ? 154.802 111.759 158.927 1.00 57.40  ? 123  SER C CB    1 
ATOM   10722 O  OG    . SER C 2 108  ? 154.756 111.514 157.533 1.00 57.40  ? 123  SER C OG    1 
ATOM   10723 N  N     . PRO C 2 109  ? 153.280 108.666 158.808 1.00 57.28  ? 124  PRO C N     1 
ATOM   10724 C  CA    . PRO C 2 109  ? 153.550 107.223 158.706 1.00 57.28  ? 124  PRO C CA    1 
ATOM   10725 C  C     . PRO C 2 109  ? 154.860 106.889 158.011 1.00 57.28  ? 124  PRO C C     1 
ATOM   10726 O  O     . PRO C 2 109  ? 155.355 105.766 158.169 1.00 57.28  ? 124  PRO C O     1 
ATOM   10727 C  CB    . PRO C 2 109  ? 152.345 106.696 157.915 1.00 57.28  ? 124  PRO C CB    1 
ATOM   10728 C  CG    . PRO C 2 109  ? 151.850 107.878 157.152 1.00 57.28  ? 124  PRO C CG    1 
ATOM   10729 C  CD    . PRO C 2 109  ? 152.097 109.068 158.031 1.00 57.28  ? 124  PRO C CD    1 
ATOM   10730 N  N     . GLU C 2 110  ? 155.437 107.821 157.248 1.00 59.86  ? 125  GLU C N     1 
ATOM   10731 C  CA    . GLU C 2 110  ? 156.712 107.578 156.583 1.00 59.86  ? 125  GLU C CA    1 
ATOM   10732 C  C     . GLU C 2 110  ? 157.883 107.499 157.554 1.00 59.86  ? 125  GLU C C     1 
ATOM   10733 O  O     . GLU C 2 110  ? 158.974 107.085 157.147 1.00 59.86  ? 125  GLU C O     1 
ATOM   10734 C  CB    . GLU C 2 110  ? 156.983 108.672 155.548 1.00 59.86  ? 125  GLU C CB    1 
ATOM   10735 C  CG    . GLU C 2 110  ? 155.933 108.768 154.453 1.00 59.86  ? 125  GLU C CG    1 
ATOM   10736 C  CD    . GLU C 2 110  ? 155.910 107.547 153.553 1.00 59.86  ? 125  GLU C CD    1 
ATOM   10737 O  OE1   . GLU C 2 110  ? 156.943 106.852 153.459 1.00 59.86  ? 125  GLU C OE1   1 
ATOM   10738 O  OE2   . GLU C 2 110  ? 154.855 107.283 152.940 1.00 59.86  ? 125  GLU C OE2   1 
ATOM   10739 N  N     . SER C 2 111  ? 157.690 107.883 158.811 1.00 55.52  ? 126  SER C N     1 
ATOM   10740 C  CA    . SER C 2 111  ? 158.753 107.820 159.803 1.00 55.52  ? 126  SER C CA    1 
ATOM   10741 C  C     . SER C 2 111  ? 158.476 106.720 160.821 1.00 55.52  ? 126  SER C C     1 
ATOM   10742 O  O     . SER C 2 111  ? 157.555 105.922 160.650 1.00 55.52  ? 126  SER C O     1 
ATOM   10743 C  CB    . SER C 2 111  ? 158.910 109.167 160.509 1.00 55.52  ? 126  SER C CB    1 
ATOM   10744 O  OG    . SER C 2 111  ? 159.217 110.194 159.584 1.00 55.52  ? 126  SER C OG    1 
ATOM   10745 N  N     . LEU C 2 130  ? 158.948 106.124 169.845 1.00 72.00  ? 145  LEU C N     1 
ATOM   10746 C  CA    . LEU C 2 130  ? 157.678 106.565 170.409 1.00 72.00  ? 145  LEU C CA    1 
ATOM   10747 C  C     . LEU C 2 130  ? 157.887 107.640 171.467 1.00 72.00  ? 145  LEU C C     1 
ATOM   10748 O  O     . LEU C 2 130  ? 157.005 108.462 171.712 1.00 72.00  ? 145  LEU C O     1 
ATOM   10749 C  CB    . LEU C 2 130  ? 156.916 105.383 171.009 1.00 72.00  ? 145  LEU C CB    1 
ATOM   10750 C  CG    . LEU C 2 130  ? 156.463 104.298 170.032 1.00 72.00  ? 145  LEU C CG    1 
ATOM   10751 C  CD1   . LEU C 2 130  ? 155.606 103.262 170.741 1.00 72.00  ? 145  LEU C CD1   1 
ATOM   10752 C  CD2   . LEU C 2 130  ? 155.707 104.916 168.876 1.00 72.00  ? 145  LEU C CD2   1 
ATOM   10753 N  N     . GLU C 2 131  ? 159.064 107.630 172.095 1.00 74.48  ? 146  GLU C N     1 
ATOM   10754 C  CA    . GLU C 2 131  ? 159.365 108.625 173.116 1.00 74.48  ? 146  GLU C CA    1 
ATOM   10755 C  C     . GLU C 2 131  ? 159.625 110.002 172.521 1.00 74.48  ? 146  GLU C C     1 
ATOM   10756 O  O     . GLU C 2 131  ? 159.608 110.994 173.256 1.00 74.48  ? 146  GLU C O     1 
ATOM   10757 C  CB    . GLU C 2 131  ? 160.567 108.179 173.951 1.00 74.48  ? 146  GLU C CB    1 
ATOM   10758 C  CG    . GLU C 2 131  ? 160.366 106.848 174.660 1.00 74.48  ? 146  GLU C CG    1 
ATOM   10759 C  CD    . GLU C 2 131  ? 159.207 106.875 175.640 1.00 74.48  ? 146  GLU C CD    1 
ATOM   10760 O  OE1   . GLU C 2 131  ? 158.958 107.938 176.246 1.00 74.48  ? 146  GLU C OE1   1 
ATOM   10761 O  OE2   . GLU C 2 131  ? 158.542 105.831 175.802 1.00 74.48  ? 146  GLU C OE2   1 
ATOM   10762 N  N     . ASN C 2 132  ? 159.873 110.084 171.217 1.00 72.97  ? 147  ASN C N     1 
ATOM   10763 C  CA    . ASN C 2 132  ? 160.021 111.360 170.532 1.00 72.97  ? 147  ASN C CA    1 
ATOM   10764 C  C     . ASN C 2 132  ? 158.719 111.844 169.903 1.00 72.97  ? 147  ASN C C     1 
ATOM   10765 O  O     . ASN C 2 132  ? 158.692 112.938 169.330 1.00 72.97  ? 147  ASN C O     1 
ATOM   10766 C  CB    . ASN C 2 132  ? 161.113 111.255 169.462 1.00 72.97  ? 147  ASN C CB    1 
ATOM   10767 C  CG    . ASN C 2 132  ? 161.615 112.610 169.007 1.00 72.97  ? 147  ASN C CG    1 
ATOM   10768 O  OD1   . ASN C 2 132  ? 162.478 113.212 169.645 1.00 72.97  ? 147  ASN C OD1   1 
ATOM   10769 N  ND2   . ASN C 2 132  ? 161.077 113.097 167.896 1.00 72.97  ? 147  ASN C ND2   1 
ATOM   10770 N  N     . LEU C 2 133  ? 157.641 111.061 170.000 1.00 72.81  ? 148  LEU C N     1 
ATOM   10771 C  CA    . LEU C 2 133  ? 156.345 111.483 169.480 1.00 72.81  ? 148  LEU C CA    1 
ATOM   10772 C  C     . LEU C 2 133  ? 155.679 112.537 170.349 1.00 72.81  ? 148  LEU C C     1 
ATOM   10773 O  O     . LEU C 2 133  ? 154.709 113.160 169.904 1.00 72.81  ? 148  LEU C O     1 
ATOM   10774 C  CB    . LEU C 2 133  ? 155.409 110.282 169.339 1.00 72.81  ? 148  LEU C CB    1 
ATOM   10775 C  CG    . LEU C 2 133  ? 155.810 109.202 168.338 1.00 72.81  ? 148  LEU C CG    1 
ATOM   10776 C  CD1   . LEU C 2 133  ? 154.622 108.304 168.035 1.00 72.81  ? 148  LEU C CD1   1 
ATOM   10777 C  CD2   . LEU C 2 133  ? 156.364 109.825 167.066 1.00 72.81  ? 148  LEU C CD2   1 
ATOM   10778 N  N     . LEU C 2 134  ? 156.160 112.741 171.571 1.00 69.01  ? 149  LEU C N     1 
ATOM   10779 C  CA    . LEU C 2 134  ? 155.635 113.762 172.461 1.00 69.01  ? 149  LEU C CA    1 
ATOM   10780 C  C     . LEU C 2 134  ? 156.531 114.990 172.520 1.00 69.01  ? 149  LEU C C     1 
ATOM   10781 O  O     . LEU C 2 134  ? 156.376 115.817 173.424 1.00 69.01  ? 149  LEU C O     1 
ATOM   10782 C  CB    . LEU C 2 134  ? 155.442 113.186 173.865 1.00 69.01  ? 149  LEU C CB    1 
ATOM   10783 C  CG    . LEU C 2 134  ? 154.738 111.830 173.949 1.00 69.01  ? 149  LEU C CG    1 
ATOM   10784 C  CD1   . LEU C 2 134  ? 154.588 111.392 175.398 1.00 69.01  ? 149  LEU C CD1   1 
ATOM   10785 C  CD2   . LEU C 2 134  ? 153.385 111.875 173.257 1.00 69.01  ? 149  LEU C CD2   1 
ATOM   10786 N  N     . LYS C 2 135  ? 157.466 115.126 171.581 1.00 70.38  ? 150  LYS C N     1 
ATOM   10787 C  CA    . LYS C 2 135  ? 158.441 116.208 171.603 1.00 70.38  ? 150  LYS C CA    1 
ATOM   10788 C  C     . LYS C 2 135  ? 158.312 117.149 170.417 1.00 70.38  ? 150  LYS C C     1 
ATOM   10789 O  O     . LYS C 2 135  ? 158.208 118.366 170.608 1.00 70.38  ? 150  LYS C O     1 
ATOM   10790 C  CB    . LYS C 2 135  ? 159.863 115.626 171.654 1.00 70.38  ? 150  LYS C CB    1 
ATOM   10791 C  CG    . LYS C 2 135  ? 160.961 116.674 171.670 1.00 70.38  ? 150  LYS C CG    1 
ATOM   10792 C  CD    . LYS C 2 135  ? 162.334 116.026 171.689 1.00 70.38  ? 150  LYS C CD    1 
ATOM   10793 C  CE    . LYS C 2 135  ? 162.499 115.123 172.898 1.00 70.38  ? 150  LYS C CE    1 
ATOM   10794 N  NZ    . LYS C 2 135  ? 163.833 114.463 172.915 1.00 70.38  ? 150  LYS C NZ    1 
ATOM   10795 N  N     . THR C 2 136  ? 158.322 116.624 169.190 1.00 65.19  ? 151  THR C N     1 
ATOM   10796 C  CA    . THR C 2 136  ? 158.303 117.455 167.991 1.00 65.19  ? 151  THR C CA    1 
ATOM   10797 C  C     . THR C 2 136  ? 157.135 117.119 167.070 1.00 65.19  ? 151  THR C C     1 
ATOM   10798 O  O     . THR C 2 136  ? 157.177 117.446 165.880 1.00 65.19  ? 151  THR C O     1 
ATOM   10799 C  CB    . THR C 2 136  ? 159.625 117.327 167.230 1.00 65.19  ? 151  THR C CB    1 
ATOM   10800 O  OG1   . THR C 2 136  ? 159.850 115.955 166.885 1.00 65.19  ? 151  THR C OG1   1 
ATOM   10801 C  CG2   . THR C 2 136  ? 160.782 117.828 168.082 1.00 65.19  ? 151  THR C CG2   1 
ATOM   10802 N  N     . SER C 2 137  ? 156.093 116.480 167.592 1.00 62.08  ? 152  SER C N     1 
ATOM   10803 C  CA    . SER C 2 137  ? 154.933 116.100 166.798 1.00 62.08  ? 152  SER C CA    1 
ATOM   10804 C  C     . SER C 2 137  ? 153.778 117.046 167.097 1.00 62.08  ? 152  SER C C     1 
ATOM   10805 O  O     . SER C 2 137  ? 153.406 117.230 168.260 1.00 62.08  ? 152  SER C O     1 
ATOM   10806 C  CB    . SER C 2 137  ? 154.527 114.655 167.088 1.00 62.08  ? 152  SER C CB    1 
ATOM   10807 O  OG    . SER C 2 137  ? 153.412 114.272 166.306 1.00 62.08  ? 152  SER C OG    1 
ATOM   10808 N  N     . GLY C 2 138  ? 153.216 117.641 166.046 1.00 58.22  ? 153  GLY C N     1 
ATOM   10809 C  CA    . GLY C 2 138  ? 152.119 118.566 166.226 1.00 58.22  ? 153  GLY C CA    1 
ATOM   10810 C  C     . GLY C 2 138  ? 150.864 117.880 166.727 1.00 58.22  ? 153  GLY C C     1 
ATOM   10811 O  O     . GLY C 2 138  ? 150.668 116.674 166.570 1.00 58.22  ? 153  GLY C O     1 
ATOM   10812 N  N     . LYS C 2 139  ? 149.993 118.671 167.346 1.00 52.56  ? 154  LYS C N     1 
ATOM   10813 C  CA    . LYS C 2 139  ? 148.769 118.155 167.934 1.00 52.56  ? 154  LYS C CA    1 
ATOM   10814 C  C     . LYS C 2 139  ? 147.577 118.983 167.479 1.00 52.56  ? 154  LYS C C     1 
ATOM   10815 O  O     . LYS C 2 139  ? 147.695 120.183 167.217 1.00 52.56  ? 154  LYS C O     1 
ATOM   10816 C  CB    . LYS C 2 139  ? 148.838 118.147 169.465 1.00 52.56  ? 154  LYS C CB    1 
ATOM   10817 C  CG    . LYS C 2 139  ? 148.967 119.519 170.096 1.00 52.56  ? 154  LYS C CG    1 
ATOM   10818 C  CD    . LYS C 2 139  ? 148.959 119.411 171.609 1.00 52.56  ? 154  LYS C CD    1 
ATOM   10819 C  CE    . LYS C 2 139  ? 148.893 120.775 172.265 1.00 52.56  ? 154  LYS C CE    1 
ATOM   10820 N  NZ    . LYS C 2 139  ? 148.783 120.663 173.745 1.00 52.56  ? 154  LYS C NZ    1 
ATOM   10821 N  N     . LEU C 2 140  ? 146.428 118.321 167.382 1.00 45.97  ? 155  LEU C N     1 
ATOM   10822 C  CA    . LEU C 2 140  ? 145.197 119.000 167.011 1.00 45.97  ? 155  LEU C CA    1 
ATOM   10823 C  C     . LEU C 2 140  ? 144.778 119.973 168.105 1.00 45.97  ? 155  LEU C C     1 
ATOM   10824 O  O     . LEU C 2 140  ? 144.908 119.685 169.298 1.00 45.97  ? 155  LEU C O     1 
ATOM   10825 C  CB    . LEU C 2 140  ? 144.086 117.984 166.760 1.00 45.97  ? 155  LEU C CB    1 
ATOM   10826 C  CG    . LEU C 2 140  ? 144.297 117.004 165.608 1.00 45.97  ? 155  LEU C CG    1 
ATOM   10827 C  CD1   . LEU C 2 140  ? 143.155 116.009 165.551 1.00 45.97  ? 155  LEU C CD1   1 
ATOM   10828 C  CD2   . LEU C 2 140  ? 144.419 117.751 164.294 1.00 45.97  ? 155  LEU C CD2   1 
ATOM   10829 N  N     . ARG C 2 141  ? 144.274 121.133 167.693 1.00 39.39  ? 156  ARG C N     1 
ATOM   10830 C  CA    . ARG C 2 141  ? 143.842 122.139 168.652 1.00 39.39  ? 156  ARG C CA    1 
ATOM   10831 C  C     . ARG C 2 141  ? 142.625 121.654 169.430 1.00 39.39  ? 156  ARG C C     1 
ATOM   10832 O  O     . ARG C 2 141  ? 141.726 121.011 168.880 1.00 39.39  ? 156  ARG C O     1 
ATOM   10833 C  CB    . ARG C 2 141  ? 143.526 123.454 167.940 1.00 39.39  ? 156  ARG C CB    1 
ATOM   10834 C  CG    . ARG C 2 141  ? 142.349 123.380 166.985 1.00 39.39  ? 156  ARG C CG    1 
ATOM   10835 C  CD    . ARG C 2 141  ? 142.171 124.677 166.218 1.00 39.39  ? 156  ARG C CD    1 
ATOM   10836 N  NE    . ARG C 2 141  ? 140.969 124.656 165.393 1.00 39.39  ? 156  ARG C NE    1 
ATOM   10837 C  CZ    . ARG C 2 141  ? 140.661 125.581 164.496 1.00 39.39  ? 156  ARG C CZ    1 
ATOM   10838 N  NH1   . ARG C 2 141  ? 141.450 126.620 164.276 1.00 39.39  ? 156  ARG C NH1   1 
ATOM   10839 N  NH2   . ARG C 2 141  ? 139.534 125.462 163.802 1.00 39.39  ? 156  ARG C NH2   1 
ATOM   10840 N  N     . ALA C 2 142  ? 142.609 121.951 170.728 1.00 40.21  ? 157  ALA C N     1 
ATOM   10841 C  CA    . ALA C 2 142  ? 141.474 121.627 171.581 1.00 40.21  ? 157  ALA C CA    1 
ATOM   10842 C  C     . ALA C 2 142  ? 140.514 122.791 171.754 1.00 40.21  ? 157  ALA C C     1 
ATOM   10843 O  O     . ALA C 2 142  ? 139.307 122.571 171.894 1.00 40.21  ? 157  ALA C O     1 
ATOM   10844 C  CB    . ALA C 2 142  ? 141.959 121.169 172.960 1.00 40.21  ? 157  ALA C CB    1 
ATOM   10845 N  N     . THR C 2 143  ? 141.026 124.020 171.752 1.00 41.61  ? 158  THR C N     1 
ATOM   10846 C  CA    . THR C 2 143  ? 140.206 125.219 171.821 1.00 41.61  ? 158  THR C CA    1 
ATOM   10847 C  C     . THR C 2 143  ? 140.783 126.265 170.880 1.00 41.61  ? 158  THR C C     1 
ATOM   10848 O  O     . THR C 2 143  ? 141.990 126.299 170.631 1.00 41.61  ? 158  THR C O     1 
ATOM   10849 C  CB    . THR C 2 143  ? 140.137 125.785 173.246 1.00 41.61  ? 158  THR C CB    1 
ATOM   10850 O  OG1   . THR C 2 143  ? 141.455 125.838 173.804 1.00 41.61  ? 158  THR C OG1   1 
ATOM   10851 C  CG2   . THR C 2 143  ? 139.245 124.922 174.127 1.00 41.61  ? 158  THR C CG2   1 
ATOM   10852 N  N     . LEU C 2 144  ? 139.905 127.126 170.364 1.00 37.36  ? 159  LEU C N     1 
ATOM   10853 C  CA    . LEU C 2 144  ? 140.326 128.185 169.455 1.00 37.36  ? 159  LEU C CA    1 
ATOM   10854 C  C     . LEU C 2 144  ? 141.121 129.281 170.148 1.00 37.36  ? 159  LEU C C     1 
ATOM   10855 O  O     . LEU C 2 144  ? 141.648 130.162 169.461 1.00 37.36  ? 159  LEU C O     1 
ATOM   10856 C  CB    . LEU C 2 144  ? 139.113 128.813 168.770 1.00 37.36  ? 159  LEU C CB    1 
ATOM   10857 C  CG    . LEU C 2 144  ? 138.200 127.903 167.955 1.00 37.36  ? 159  LEU C CG    1 
ATOM   10858 C  CD1   . LEU C 2 144  ? 137.252 128.738 167.120 1.00 37.36  ? 159  LEU C CD1   1 
ATOM   10859 C  CD2   . LEU C 2 144  ? 139.022 126.990 167.076 1.00 37.36  ? 159  LEU C CD2   1 
ATOM   10860 N  N     . LEU C 2 145  ? 141.206 129.253 171.479 1.00 41.14  ? 160  LEU C N     1 
ATOM   10861 C  CA    . LEU C 2 145  ? 141.804 130.360 172.217 1.00 41.14  ? 160  LEU C CA    1 
ATOM   10862 C  C     . LEU C 2 145  ? 143.246 130.610 171.796 1.00 41.14  ? 160  LEU C C     1 
ATOM   10863 O  O     . LEU C 2 145  ? 143.648 131.762 171.597 1.00 41.14  ? 160  LEU C O     1 
ATOM   10864 C  CB    . LEU C 2 145  ? 141.728 130.081 173.716 1.00 41.14  ? 160  LEU C CB    1 
ATOM   10865 C  CG    . LEU C 2 145  ? 142.469 131.056 174.626 1.00 41.14  ? 160  LEU C CG    1 
ATOM   10866 C  CD1   . LEU C 2 145  ? 141.825 132.430 174.575 1.00 41.14  ? 160  LEU C CD1   1 
ATOM   10867 C  CD2   . LEU C 2 145  ? 142.503 130.520 176.043 1.00 41.14  ? 160  LEU C CD2   1 
ATOM   10868 N  N     . HIS C 2 146  ? 144.041 129.547 171.649 1.00 47.37  ? 161  HIS C N     1 
ATOM   10869 C  CA    . HIS C 2 146  ? 145.454 129.732 171.336 1.00 47.37  ? 161  HIS C CA    1 
ATOM   10870 C  C     . HIS C 2 146  ? 145.661 130.228 169.911 1.00 47.37  ? 161  HIS C C     1 
ATOM   10871 O  O     . HIS C 2 146  ? 146.632 130.944 169.643 1.00 47.37  ? 161  HIS C O     1 
ATOM   10872 C  CB    . HIS C 2 146  ? 146.222 128.430 171.559 1.00 47.37  ? 161  HIS C CB    1 
ATOM   10873 C  CG    . HIS C 2 146  ? 147.700 128.564 171.361 1.00 47.37  ? 161  HIS C CG    1 
ATOM   10874 N  ND1   . HIS C 2 146  ? 148.309 128.356 170.143 1.00 47.37  ? 161  HIS C ND1   1 
ATOM   10875 C  CD2   . HIS C 2 146  ? 148.689 128.891 172.226 1.00 47.37  ? 161  HIS C CD2   1 
ATOM   10876 C  CE1   . HIS C 2 146  ? 149.611 128.546 170.266 1.00 47.37  ? 161  HIS C CE1   1 
ATOM   10877 N  NE2   . HIS C 2 146  ? 149.867 128.872 171.520 1.00 47.37  ? 161  HIS C NE2   1 
ATOM   10878 N  N     . GLY C 2 147  ? 144.774 129.858 168.988 1.00 44.74  ? 162  GLY C N     1 
ATOM   10879 C  CA    . GLY C 2 147  ? 144.885 130.365 167.630 1.00 44.74  ? 162  GLY C CA    1 
ATOM   10880 C  C     . GLY C 2 147  ? 144.667 131.864 167.549 1.00 44.74  ? 162  GLY C C     1 
ATOM   10881 O  O     . GLY C 2 147  ? 145.345 132.558 166.786 1.00 44.74  ? 162  GLY C O     1 
ATOM   10882 N  N     . ALA C 2 148  ? 143.715 132.382 168.329 1.00 46.89  ? 163  ALA C N     1 
ATOM   10883 C  CA    . ALA C 2 148  ? 143.454 133.817 168.332 1.00 46.89  ? 163  ALA C CA    1 
ATOM   10884 C  C     . ALA C 2 148  ? 144.643 134.600 168.873 1.00 46.89  ? 163  ALA C C     1 
ATOM   10885 O  O     . ALA C 2 148  ? 144.987 135.661 168.342 1.00 46.89  ? 163  ALA C O     1 
ATOM   10886 C  CB    . ALA C 2 148  ? 142.200 134.120 169.150 1.00 46.89  ? 163  ALA C CB    1 
ATOM   10887 N  N     . LEU C 2 149  ? 145.284 134.090 169.928 1.00 48.59  ? 164  LEU C N     1 
ATOM   10888 C  CA    . LEU C 2 149  ? 146.381 134.810 170.565 1.00 48.59  ? 164  LEU C CA    1 
ATOM   10889 C  C     . LEU C 2 149  ? 147.588 134.975 169.652 1.00 48.59  ? 164  LEU C C     1 
ATOM   10890 O  O     . LEU C 2 149  ? 148.407 135.867 169.892 1.00 48.59  ? 164  LEU C O     1 
ATOM   10891 C  CB    . LEU C 2 149  ? 146.806 134.099 171.849 1.00 48.59  ? 164  LEU C CB    1 
ATOM   10892 C  CG    . LEU C 2 149  ? 146.150 134.540 173.159 1.00 48.59  ? 164  LEU C CG    1 
ATOM   10893 C  CD1   . LEU C 2 149  ? 144.639 134.410 173.096 1.00 48.59  ? 164  LEU C CD1   1 
ATOM   10894 C  CD2   . LEU C 2 149  ? 146.704 133.737 174.324 1.00 48.59  ? 164  LEU C CD2   1 
ATOM   10895 N  N     . GLU C 2 150  ? 147.723 134.143 168.620 1.00 52.31  ? 165  GLU C N     1 
ATOM   10896 C  CA    . GLU C 2 150  ? 148.834 134.293 167.689 1.00 52.31  ? 165  GLU C CA    1 
ATOM   10897 C  C     . GLU C 2 150  ? 148.593 135.389 166.661 1.00 52.31  ? 165  GLU C C     1 
ATOM   10898 O  O     . GLU C 2 150  ? 149.548 135.841 166.022 1.00 52.31  ? 165  GLU C O     1 
ATOM   10899 C  CB    . GLU C 2 150  ? 149.112 132.968 166.979 1.00 52.31  ? 165  GLU C CB    1 
ATOM   10900 C  CG    . GLU C 2 150  ? 149.715 131.907 167.883 1.00 52.31  ? 165  GLU C CG    1 
ATOM   10901 C  CD    . GLU C 2 150  ? 149.969 130.601 167.162 1.00 52.31  ? 165  GLU C CD    1 
ATOM   10902 O  OE1   . GLU C 2 150  ? 149.342 130.372 166.107 1.00 52.31  ? 165  GLU C OE1   1 
ATOM   10903 O  OE2   . GLU C 2 150  ? 150.798 129.805 167.650 1.00 52.31  ? 165  GLU C OE2   1 
ATOM   10904 N  N     . HIS C 2 151  ? 147.347 135.823 166.491 1.00 49.60  ? 166  HIS C N     1 
ATOM   10905 C  CA    . HIS C 2 151  ? 147.006 136.910 165.585 1.00 49.60  ? 166  HIS C CA    1 
ATOM   10906 C  C     . HIS C 2 151  ? 146.985 138.265 166.274 1.00 49.60  ? 166  HIS C C     1 
ATOM   10907 O  O     . HIS C 2 151  ? 146.557 139.248 165.661 1.00 49.60  ? 166  HIS C O     1 
ATOM   10908 C  CB    . HIS C 2 151  ? 145.652 136.646 164.926 1.00 49.60  ? 166  HIS C CB    1 
ATOM   10909 C  CG    . HIS C 2 151  ? 145.715 135.675 163.792 1.00 49.60  ? 166  HIS C CG    1 
ATOM   10910 N  ND1   . HIS C 2 151  ? 145.854 136.074 162.480 1.00 49.60  ? 166  HIS C ND1   1 
ATOM   10911 C  CD2   . HIS C 2 151  ? 145.662 134.323 163.771 1.00 49.60  ? 166  HIS C CD2   1 
ATOM   10912 C  CE1   . HIS C 2 151  ? 145.882 135.009 161.699 1.00 49.60  ? 166  HIS C CE1   1 
ATOM   10913 N  NE2   . HIS C 2 151  ? 145.767 133.934 162.458 1.00 49.60  ? 166  HIS C NE2   1 
ATOM   10914 N  N     . TYR C 2 152  ? 147.417 138.331 167.536 1.00 63.29  ? 167  TYR C N     1 
ATOM   10915 C  CA    . TYR C 2 152  ? 147.395 139.593 168.270 1.00 63.29  ? 167  TYR C CA    1 
ATOM   10916 C  C     . TYR C 2 152  ? 148.175 140.674 167.532 1.00 63.29  ? 167  TYR C C     1 
ATOM   10917 O  O     . TYR C 2 152  ? 147.667 141.777 167.308 1.00 63.29  ? 167  TYR C O     1 
ATOM   10918 C  CB    . TYR C 2 152  ? 147.953 139.383 169.679 1.00 63.29  ? 167  TYR C CB    1 
ATOM   10919 C  CG    . TYR C 2 152  ? 148.176 140.661 170.453 1.00 63.29  ? 167  TYR C CG    1 
ATOM   10920 C  CD1   . TYR C 2 152  ? 147.129 141.294 171.106 1.00 63.29  ? 167  TYR C CD1   1 
ATOM   10921 C  CD2   . TYR C 2 152  ? 149.439 141.232 170.537 1.00 63.29  ? 167  TYR C CD2   1 
ATOM   10922 C  CE1   . TYR C 2 152  ? 147.332 142.463 171.815 1.00 63.29  ? 167  TYR C CE1   1 
ATOM   10923 C  CE2   . TYR C 2 152  ? 149.650 142.398 171.242 1.00 63.29  ? 167  TYR C CE2   1 
ATOM   10924 C  CZ    . TYR C 2 152  ? 148.596 143.009 171.880 1.00 63.29  ? 167  TYR C CZ    1 
ATOM   10925 O  OH    . TYR C 2 152  ? 148.807 144.172 172.585 1.00 63.29  ? 167  TYR C OH    1 
ATOM   10926 N  N     . VAL C 2 153  ? 149.411 140.371 167.132 1.00 65.11  ? 168  VAL C N     1 
ATOM   10927 C  CA    . VAL C 2 153  ? 150.188 141.329 166.350 1.00 65.11  ? 168  VAL C CA    1 
ATOM   10928 C  C     . VAL C 2 153  ? 149.575 141.510 164.966 1.00 65.11  ? 168  VAL C C     1 
ATOM   10929 O  O     . VAL C 2 153  ? 149.591 142.612 164.404 1.00 65.11  ? 168  VAL C O     1 
ATOM   10930 C  CB    . VAL C 2 153  ? 151.660 140.887 166.268 1.00 65.11  ? 168  VAL C CB    1 
ATOM   10931 C  CG1   . VAL C 2 153  ? 152.460 141.844 165.396 1.00 65.11  ? 168  VAL C CG1   1 
ATOM   10932 C  CG2   . VAL C 2 153  ? 152.265 140.808 167.659 1.00 65.11  ? 168  VAL C CG2   1 
ATOM   10933 N  N     . ASN C 2 154  ? 149.023 140.434 164.399 1.00 67.96  ? 169  ASN C N     1 
ATOM   10934 C  CA    . ASN C 2 154  ? 148.496 140.496 163.039 1.00 67.96  ? 169  ASN C CA    1 
ATOM   10935 C  C     . ASN C 2 154  ? 147.351 141.494 162.928 1.00 67.96  ? 169  ASN C C     1 
ATOM   10936 O  O     . ASN C 2 154  ? 147.282 142.265 161.964 1.00 67.96  ? 169  ASN C O     1 
ATOM   10937 C  CB    . ASN C 2 154  ? 148.042 139.107 162.591 1.00 67.96  ? 169  ASN C CB    1 
ATOM   10938 C  CG    . ASN C 2 154  ? 149.138 138.068 162.716 1.00 67.96  ? 169  ASN C CG    1 
ATOM   10939 O  OD1   . ASN C 2 154  ? 150.317 138.404 162.823 1.00 67.96  ? 169  ASN C OD1   1 
ATOM   10940 N  ND2   . ASN C 2 154  ? 148.754 136.798 162.699 1.00 67.96  ? 169  ASN C ND2   1 
ATOM   10941 N  N     . CYS C 2 155  ? 146.443 141.496 163.901 1.00 71.04  ? 170  CYS C N     1 
ATOM   10942 C  CA    . CYS C 2 155  ? 145.337 142.443 163.924 1.00 71.04  ? 170  CYS C CA    1 
ATOM   10943 C  C     . CYS C 2 155  ? 145.620 143.662 164.792 1.00 71.04  ? 170  CYS C C     1 
ATOM   10944 O  O     . CYS C 2 155  ? 144.750 144.529 164.920 1.00 71.04  ? 170  CYS C O     1 
ATOM   10945 C  CB    . CYS C 2 155  ? 144.058 141.750 164.401 1.00 71.04  ? 170  CYS C CB    1 
ATOM   10946 S  SG    . CYS C 2 155  ? 143.437 140.491 163.263 1.00 71.04  ? 170  CYS C SG    1 
ATOM   10947 N  N     . LEU C 2 156  ? 146.807 143.746 165.395 1.00 69.06  ? 171  LEU C N     1 
ATOM   10948 C  CA    . LEU C 2 156  ? 147.164 144.931 166.167 1.00 69.06  ? 171  LEU C CA    1 
ATOM   10949 C  C     . LEU C 2 156  ? 147.376 146.135 165.257 1.00 69.06  ? 171  LEU C C     1 
ATOM   10950 O  O     . LEU C 2 156  ? 146.960 147.251 165.588 1.00 69.06  ? 171  LEU C O     1 
ATOM   10951 C  CB    . LEU C 2 156  ? 148.418 144.650 166.995 1.00 69.06  ? 171  LEU C CB    1 
ATOM   10952 C  CG    . LEU C 2 156  ? 148.738 145.600 168.151 1.00 69.06  ? 171  LEU C CG    1 
ATOM   10953 C  CD1   . LEU C 2 156  ? 147.774 145.386 169.306 1.00 69.06  ? 171  LEU C CD1   1 
ATOM   10954 C  CD2   . LEU C 2 156  ? 150.178 145.426 168.606 1.00 69.06  ? 171  LEU C CD2   1 
ATOM   10955 N  N     . ASP C 2 157  ? 148.021 145.927 164.107 1.00 68.52  ? 172  ASP C N     1 
ATOM   10956 C  CA    . ASP C 2 157  ? 148.241 147.023 163.170 1.00 68.52  ? 172  ASP C CA    1 
ATOM   10957 C  C     . ASP C 2 157  ? 146.957 147.406 162.447 1.00 68.52  ? 172  ASP C C     1 
ATOM   10958 O  O     . ASP C 2 157  ? 146.821 148.545 161.986 1.00 68.52  ? 172  ASP C O     1 
ATOM   10959 C  CB    . ASP C 2 157  ? 149.325 146.639 162.163 1.00 68.52  ? 172  ASP C CB    1 
ATOM   10960 C  CG    . ASP C 2 157  ? 149.807 147.820 161.342 1.00 68.52  ? 172  ASP C CG    1 
ATOM   10961 O  OD1   . ASP C 2 157  ? 149.559 148.974 161.748 1.00 68.52  ? 172  ASP C OD1   1 
ATOM   10962 O  OD2   . ASP C 2 157  ? 150.433 147.593 160.285 1.00 68.52  ? 172  ASP C OD2   1 
ATOM   10963 N  N     . LEU C 2 158  ? 146.010 146.472 162.334 1.00 63.85  ? 173  LEU C N     1 
ATOM   10964 C  CA    . LEU C 2 158  ? 144.749 146.769 161.663 1.00 63.85  ? 173  LEU C CA    1 
ATOM   10965 C  C     . LEU C 2 158  ? 143.951 147.819 162.427 1.00 63.85  ? 173  LEU C C     1 
ATOM   10966 O  O     . LEU C 2 158  ? 143.320 148.694 161.821 1.00 63.85  ? 173  LEU C O     1 
ATOM   10967 C  CB    . LEU C 2 158  ? 143.936 145.487 161.491 1.00 63.85  ? 173  LEU C CB    1 
ATOM   10968 C  CG    . LEU C 2 158  ? 142.627 145.587 160.708 1.00 63.85  ? 173  LEU C CG    1 
ATOM   10969 C  CD1   . LEU C 2 158  ? 142.849 146.297 159.383 1.00 63.85  ? 173  LEU C CD1   1 
ATOM   10970 C  CD2   . LEU C 2 158  ? 142.048 144.202 160.480 1.00 63.85  ? 173  LEU C CD2   1 
ATOM   10971 N  N     . VAL C 2 159  ? 143.965 147.749 163.756 1.00 69.78  ? 174  VAL C N     1 
ATOM   10972 C  CA    . VAL C 2 159  ? 143.246 148.703 164.594 1.00 69.78  ? 174  VAL C CA    1 
ATOM   10973 C  C     . VAL C 2 159  ? 144.178 149.846 164.969 1.00 69.78  ? 174  VAL C C     1 
ATOM   10974 O  O     . VAL C 2 159  ? 143.831 150.697 165.796 1.00 69.78  ? 174  VAL C O     1 
ATOM   10975 C  CB    . VAL C 2 159  ? 142.683 148.021 165.853 1.00 69.78  ? 174  VAL C CB    1 
ATOM   10976 C  CG1   . VAL C 2 159  ? 141.845 146.822 165.469 1.00 69.78  ? 174  VAL C CG1   1 
ATOM   10977 C  CG2   . VAL C 2 159  ? 143.815 147.604 166.780 1.00 69.78  ? 174  VAL C CG2   1 
ATOM   10978 N  N     . ASN C 2 160  ? 145.363 149.872 164.355 1.00 70.29  ? 175  ASN C N     1 
ATOM   10979 C  CA    . ASN C 2 160  ? 146.411 150.841 164.685 1.00 70.29  ? 175  ASN C CA    1 
ATOM   10980 C  C     . ASN C 2 160  ? 146.769 150.785 166.168 1.00 70.29  ? 175  ASN C C     1 
ATOM   10981 O  O     . ASN C 2 160  ? 147.017 151.811 166.805 1.00 70.29  ? 175  ASN C O     1 
ATOM   10982 C  CB    . ASN C 2 160  ? 146.012 152.260 164.272 1.00 70.29  ? 175  ASN C CB    1 
ATOM   10983 C  CG    . ASN C 2 160  ? 145.891 152.417 162.770 1.00 70.29  ? 175  ASN C CG    1 
ATOM   10984 O  OD1   . ASN C 2 160  ? 146.852 152.780 162.093 1.00 70.29  ? 175  ASN C OD1   1 
ATOM   10985 N  ND2   . ASN C 2 160  ? 144.704 152.142 162.240 1.00 70.29  ? 175  ASN C ND2   1 
ATOM   10986 N  N     . ARG C 2 161  ? 146.795 149.568 166.720 1.00 72.34  ? 176  ARG C N     1 
ATOM   10987 C  CA    . ARG C 2 161  ? 147.215 149.327 168.102 1.00 72.34  ? 176  ARG C CA    1 
ATOM   10988 C  C     . ARG C 2 161  ? 146.357 150.106 169.097 1.00 72.34  ? 176  ARG C C     1 
ATOM   10989 O  O     . ARG C 2 161  ? 146.856 150.639 170.090 1.00 72.34  ? 176  ARG C O     1 
ATOM   10990 C  CB    . ARG C 2 161  ? 148.698 149.658 168.284 1.00 72.34  ? 176  ARG C CB    1 
ATOM   10991 C  CG    . ARG C 2 161  ? 149.607 148.947 167.297 1.00 72.34  ? 176  ARG C CG    1 
ATOM   10992 C  CD    . ARG C 2 161  ? 151.005 149.535 167.297 1.00 72.34  ? 176  ARG C CD    1 
ATOM   10993 N  NE    . ARG C 2 161  ? 151.030 150.870 166.713 1.00 72.34  ? 176  ARG C NE    1 
ATOM   10994 C  CZ    . ARG C 2 161  ? 152.133 151.577 166.509 1.00 72.34  ? 176  ARG C CZ    1 
ATOM   10995 N  NH1   . ARG C 2 161  ? 153.326 151.104 166.830 1.00 72.34  ? 176  ARG C NH1   1 
ATOM   10996 N  NH2   . ARG C 2 161  ? 152.037 152.788 165.968 1.00 72.34  ? 176  ARG C NH2   1 
ATOM   10997 N  N     . LYS C 2 162  ? 145.054 150.170 168.833 1.00 70.22  ? 177  LYS C N     1 
ATOM   10998 C  CA    . LYS C 2 162  ? 144.120 150.923 169.669 1.00 70.22  ? 177  LYS C CA    1 
ATOM   10999 C  C     . LYS C 2 162  ? 143.277 149.940 170.475 1.00 70.22  ? 177  LYS C C     1 
ATOM   11000 O  O     . LYS C 2 162  ? 142.294 149.389 169.974 1.00 70.22  ? 177  LYS C O     1 
ATOM   11001 C  CB    . LYS C 2 162  ? 143.242 151.834 168.817 1.00 70.22  ? 177  LYS C CB    1 
ATOM   11002 C  CG    . LYS C 2 162  ? 142.216 152.618 169.618 1.00 70.22  ? 177  LYS C CG    1 
ATOM   11003 C  CD    . LYS C 2 162  ? 141.289 153.410 168.714 1.00 70.22  ? 177  LYS C CD    1 
ATOM   11004 C  CE    . LYS C 2 162  ? 140.230 154.143 169.522 1.00 70.22  ? 177  LYS C CE    1 
ATOM   11005 N  NZ    . LYS C 2 162  ? 139.405 153.206 170.333 1.00 70.22  ? 177  LYS C NZ    1 
ATOM   11006 N  N     . LEU C 2 163  ? 143.668 149.722 171.727 1.00 65.14  ? 178  LEU C N     1 
ATOM   11007 C  CA    . LEU C 2 163  ? 142.857 148.921 172.625 1.00 65.14  ? 178  LEU C CA    1 
ATOM   11008 C  C     . LEU C 2 163  ? 141.566 149.662 172.970 1.00 65.14  ? 178  LEU C C     1 
ATOM   11009 O  O     . LEU C 2 163  ? 141.549 150.893 173.049 1.00 65.14  ? 178  LEU C O     1 
ATOM   11010 C  CB    . LEU C 2 163  ? 143.628 148.602 173.904 1.00 65.14  ? 178  LEU C CB    1 
ATOM   11011 C  CG    . LEU C 2 163  ? 144.693 147.508 173.816 1.00 65.14  ? 178  LEU C CG    1 
ATOM   11012 C  CD1   . LEU C 2 163  ? 145.521 147.455 175.090 1.00 65.14  ? 178  LEU C CD1   1 
ATOM   11013 C  CD2   . LEU C 2 163  ? 144.036 146.166 173.551 1.00 65.14  ? 178  LEU C CD2   1 
ATOM   11014 N  N     . PRO C 2 164  ? 140.464 148.933 173.176 1.00 59.87  ? 179  PRO C N     1 
ATOM   11015 C  CA    . PRO C 2 164  ? 140.314 147.482 173.032 1.00 59.87  ? 179  PRO C CA    1 
ATOM   11016 C  C     . PRO C 2 164  ? 140.020 147.069 171.595 1.00 59.87  ? 179  PRO C C     1 
ATOM   11017 O  O     . PRO C 2 164  ? 139.566 147.869 170.783 1.00 59.87  ? 179  PRO C O     1 
ATOM   11018 C  CB    . PRO C 2 164  ? 139.143 147.176 173.969 1.00 59.87  ? 179  PRO C CB    1 
ATOM   11019 C  CG    . PRO C 2 164  ? 138.276 148.389 173.848 1.00 59.87  ? 179  PRO C CG    1 
ATOM   11020 C  CD    . PRO C 2 164  ? 139.239 149.550 173.715 1.00 59.87  ? 179  PRO C CD    1 
ATOM   11021 N  N     . PHE C 2 165  ? 140.278 145.807 171.265 1.00 57.13  ? 180  PHE C N     1 
ATOM   11022 C  CA    . PHE C 2 165  ? 139.947 145.259 169.959 1.00 57.13  ? 180  PHE C CA    1 
ATOM   11023 C  C     . PHE C 2 165  ? 139.699 143.769 170.129 1.00 57.13  ? 180  PHE C C     1 
ATOM   11024 O  O     . PHE C 2 165  ? 140.163 143.152 171.090 1.00 57.13  ? 180  PHE C O     1 
ATOM   11025 C  CB    . PHE C 2 165  ? 141.054 145.531 168.928 1.00 57.13  ? 180  PHE C CB    1 
ATOM   11026 C  CG    . PHE C 2 165  ? 142.327 144.770 169.179 1.00 57.13  ? 180  PHE C CG    1 
ATOM   11027 C  CD1   . PHE C 2 165  ? 143.154 145.103 170.239 1.00 57.13  ? 180  PHE C CD1   1 
ATOM   11028 C  CD2   . PHE C 2 165  ? 142.706 143.736 168.341 1.00 57.13  ? 180  PHE C CD2   1 
ATOM   11029 C  CE1   . PHE C 2 165  ? 144.323 144.408 170.466 1.00 57.13  ? 180  PHE C CE1   1 
ATOM   11030 C  CE2   . PHE C 2 165  ? 143.875 143.040 168.561 1.00 57.13  ? 180  PHE C CE2   1 
ATOM   11031 C  CZ    . PHE C 2 165  ? 144.684 143.376 169.625 1.00 57.13  ? 180  PHE C CZ    1 
ATOM   11032 N  N     . GLY C 2 166  ? 138.956 143.192 169.186 1.00 43.71  ? 181  GLY C N     1 
ATOM   11033 C  CA    . GLY C 2 166  ? 138.470 141.841 169.338 1.00 43.71  ? 181  GLY C CA    1 
ATOM   11034 C  C     . GLY C 2 166  ? 138.839 140.959 168.163 1.00 43.71  ? 181  GLY C C     1 
ATOM   11035 O  O     . GLY C 2 166  ? 139.090 141.425 167.052 1.00 43.71  ? 181  GLY C O     1 
ATOM   11036 N  N     . LEU C 2 167  ? 138.864 139.658 168.441 1.00 38.52  ? 182  LEU C N     1 
ATOM   11037 C  CA    . LEU C 2 167  ? 139.107 138.624 167.445 1.00 38.52  ? 182  LEU C CA    1 
ATOM   11038 C  C     . LEU C 2 167  ? 138.026 137.568 167.579 1.00 38.52  ? 182  LEU C C     1 
ATOM   11039 O  O     . LEU C 2 167  ? 137.751 137.099 168.687 1.00 38.52  ? 182  LEU C O     1 
ATOM   11040 C  CB    . LEU C 2 167  ? 140.486 137.987 167.622 1.00 38.52  ? 182  LEU C CB    1 
ATOM   11041 C  CG    . LEU C 2 167  ? 141.696 138.912 167.520 1.00 38.52  ? 182  LEU C CG    1 
ATOM   11042 C  CD1   . LEU C 2 167  ? 142.979 138.118 167.666 1.00 38.52  ? 182  LEU C CD1   1 
ATOM   11043 C  CD2   . LEU C 2 167  ? 141.673 139.657 166.203 1.00 38.52  ? 182  LEU C CD2   1 
ATOM   11044 N  N     . ALA C 2 168  ? 137.417 137.195 166.460 1.00 28.66  ? 183  ALA C N     1 
ATOM   11045 C  CA    . ALA C 2 168  ? 136.359 136.199 166.451 1.00 28.66  ? 183  ALA C CA    1 
ATOM   11046 C  C     . ALA C 2 168  ? 136.620 135.193 165.345 1.00 28.66  ? 183  ALA C C     1 
ATOM   11047 O  O     . ALA C 2 168  ? 137.232 135.513 164.323 1.00 28.66  ? 183  ALA C O     1 
ATOM   11048 C  CB    . ALA C 2 168  ? 134.980 136.839 166.263 1.00 28.66  ? 183  ALA C CB    1 
ATOM   11049 N  N     . GLN C 2 169  ? 136.140 133.972 165.557 1.00 29.53  ? 184  GLN C N     1 
ATOM   11050 C  CA    . GLN C 2 169  ? 136.375 132.891 164.616 1.00 29.53  ? 184  GLN C CA    1 
ATOM   11051 C  C     . GLN C 2 169  ? 135.401 131.762 164.906 1.00 29.53  ? 184  GLN C C     1 
ATOM   11052 O  O     . GLN C 2 169  ? 135.133 131.450 166.067 1.00 29.53  ? 184  GLN C O     1 
ATOM   11053 C  CB    . GLN C 2 169  ? 137.817 132.383 164.709 1.00 29.53  ? 184  GLN C CB    1 
ATOM   11054 C  CG    . GLN C 2 169  ? 138.089 131.119 163.920 1.00 29.53  ? 184  GLN C CG    1 
ATOM   11055 C  CD    . GLN C 2 169  ? 139.478 130.577 164.168 1.00 29.53  ? 184  GLN C CD    1 
ATOM   11056 O  OE1   . GLN C 2 169  ? 140.048 130.772 165.241 1.00 29.53  ? 184  GLN C OE1   1 
ATOM   11057 N  NE2   . GLN C 2 169  ? 140.035 129.897 163.175 1.00 29.53  ? 184  GLN C NE2   1 
ATOM   11058 N  N     . ILE C 2 170  ? 134.872 131.166 163.845 1.00 27.05  ? 185  ILE C N     1 
ATOM   11059 C  CA    . ILE C 2 170  ? 134.052 129.967 163.934 1.00 27.05  ? 185  ILE C CA    1 
ATOM   11060 C  C     . ILE C 2 170  ? 134.819 128.854 163.238 1.00 27.05  ? 185  ILE C C     1 
ATOM   11061 O  O     . ILE C 2 170  ? 134.898 128.817 162.004 1.00 27.05  ? 185  ILE C O     1 
ATOM   11062 C  CB    . ILE C 2 170  ? 132.667 130.172 163.308 1.00 27.05  ? 185  ILE C CB    1 
ATOM   11063 C  CG1   . ILE C 2 170  ? 131.917 131.274 164.051 1.00 27.05  ? 185  ILE C CG1   1 
ATOM   11064 C  CG2   . ILE C 2 170  ? 131.878 128.874 163.320 1.00 27.05  ? 185  ILE C CG2   1 
ATOM   11065 C  CD1   . ILE C 2 170  ? 130.483 131.425 163.630 1.00 27.05  ? 185  ILE C CD1   1 
ATOM   11066 N  N     . GLY C 2 171  ? 135.393 127.952 164.026 1.00 38.49  ? 186  GLY C N     1 
ATOM   11067 C  CA    . GLY C 2 171  ? 136.158 126.850 163.483 1.00 38.49  ? 186  GLY C CA    1 
ATOM   11068 C  C     . GLY C 2 171  ? 135.796 125.536 164.136 1.00 38.49  ? 186  GLY C C     1 
ATOM   11069 O  O     . GLY C 2 171  ? 134.762 125.431 164.801 1.00 38.49  ? 186  GLY C O     1 
ATOM   11070 N  N     . VAL C 2 172  ? 136.638 124.524 163.957 1.00 40.12  ? 187  VAL C N     1 
ATOM   11071 C  CA    . VAL C 2 172  ? 136.409 123.203 164.524 1.00 40.12  ? 187  VAL C CA    1 
ATOM   11072 C  C     . VAL C 2 172  ? 137.397 122.985 165.658 1.00 40.12  ? 187  VAL C C     1 
ATOM   11073 O  O     . VAL C 2 172  ? 138.591 123.284 165.520 1.00 40.12  ? 187  VAL C O     1 
ATOM   11074 C  CB    . VAL C 2 172  ? 136.545 122.107 163.454 1.00 40.12  ? 187  VAL C CB    1 
ATOM   11075 C  CG1   . VAL C 2 172  ? 135.901 120.819 163.937 1.00 40.12  ? 187  VAL C CG1   1 
ATOM   11076 C  CG2   . VAL C 2 172  ? 135.928 122.567 162.146 1.00 40.12  ? 187  VAL C CG2   1 
ATOM   11077 N  N     . CYS C 2 173  ? 136.900 122.483 166.783 1.00 47.55  ? 188  CYS C N     1 
ATOM   11078 C  CA    . CYS C 2 173  ? 137.728 122.124 167.924 1.00 47.55  ? 188  CYS C CA    1 
ATOM   11079 C  C     . CYS C 2 173  ? 137.707 120.614 168.104 1.00 47.55  ? 188  CYS C C     1 
ATOM   11080 O  O     . CYS C 2 173  ? 136.652 119.981 167.997 1.00 47.55  ? 188  CYS C O     1 
ATOM   11081 C  CB    . CYS C 2 173  ? 137.244 122.808 169.202 1.00 47.55  ? 188  CYS C CB    1 
ATOM   11082 S  SG    . CYS C 2 173  ? 137.563 124.580 169.265 1.00 47.55  ? 188  CYS C SG    1 
ATOM   11083 N  N     . PHE C 2 174  ? 138.875 120.043 168.376 1.00 45.40  ? 189  PHE C N     1 
ATOM   11084 C  CA    . PHE C 2 174  ? 139.036 118.603 168.523 1.00 45.40  ? 189  PHE C CA    1 
ATOM   11085 C  C     . PHE C 2 174  ? 139.218 118.281 169.999 1.00 45.40  ? 189  PHE C C     1 
ATOM   11086 O  O     . PHE C 2 174  ? 140.225 118.668 170.601 1.00 45.40  ? 189  PHE C O     1 
ATOM   11087 C  CB    . PHE C 2 174  ? 140.233 118.101 167.714 1.00 45.40  ? 189  PHE C CB    1 
ATOM   11088 C  CG    . PHE C 2 174  ? 140.279 118.624 166.305 1.00 45.40  ? 189  PHE C CG    1 
ATOM   11089 C  CD1   . PHE C 2 174  ? 139.645 117.945 165.278 1.00 45.40  ? 189  PHE C CD1   1 
ATOM   11090 C  CD2   . PHE C 2 174  ? 140.963 119.790 166.007 1.00 45.40  ? 189  PHE C CD2   1 
ATOM   11091 C  CE1   . PHE C 2 174  ? 139.689 118.423 163.984 1.00 45.40  ? 189  PHE C CE1   1 
ATOM   11092 C  CE2   . PHE C 2 174  ? 141.010 120.272 164.715 1.00 45.40  ? 189  PHE C CE2   1 
ATOM   11093 C  CZ    . PHE C 2 174  ? 140.374 119.588 163.703 1.00 45.40  ? 189  PHE C CZ    1 
ATOM   11094 N  N     . HIS C 2 175  ? 138.249 117.574 170.578 1.00 52.41  ? 190  HIS C N     1 
ATOM   11095 C  CA    . HIS C 2 175  ? 138.355 117.198 171.975 1.00 52.41  ? 190  HIS C CA    1 
ATOM   11096 C  C     . HIS C 2 175  ? 138.271 115.684 172.124 1.00 52.41  ? 190  HIS C C     1 
ATOM   11097 O  O     . HIS C 2 175  ? 137.473 115.037 171.437 1.00 52.41  ? 190  HIS C O     1 
ATOM   11098 C  CB    . HIS C 2 175  ? 137.256 117.864 172.824 1.00 52.41  ? 190  HIS C CB    1 
ATOM   11099 C  CG    . HIS C 2 175  ? 135.864 117.454 172.452 1.00 52.41  ? 190  HIS C CG    1 
ATOM   11100 N  ND1   . HIS C 2 175  ? 135.045 118.232 171.663 1.00 52.41  ? 190  HIS C ND1   1 
ATOM   11101 C  CD2   . HIS C 2 175  ? 135.142 116.354 172.773 1.00 52.41  ? 190  HIS C CD2   1 
ATOM   11102 C  CE1   . HIS C 2 175  ? 133.882 117.625 171.506 1.00 52.41  ? 190  HIS C CE1   1 
ATOM   11103 N  NE2   . HIS C 2 175  ? 133.915 116.483 172.169 1.00 52.41  ? 190  HIS C NE2   1 
ATOM   11104 N  N     . PRO C 2 176  ? 139.082 115.091 173.001 1.00 51.80  ? 191  PRO C N     1 
ATOM   11105 C  CA    . PRO C 2 176  ? 139.045 113.631 173.181 1.00 51.80  ? 191  PRO C CA    1 
ATOM   11106 C  C     . PRO C 2 176  ? 137.762 113.206 173.880 1.00 51.80  ? 191  PRO C C     1 
ATOM   11107 O  O     . PRO C 2 176  ? 137.490 113.614 175.010 1.00 51.80  ? 191  PRO C O     1 
ATOM   11108 C  CB    . PRO C 2 176  ? 140.282 113.348 174.039 1.00 51.80  ? 191  PRO C CB    1 
ATOM   11109 C  CG    . PRO C 2 176  ? 140.537 114.626 174.762 1.00 51.80  ? 191  PRO C CG    1 
ATOM   11110 C  CD    . PRO C 2 176  ? 140.121 115.727 173.828 1.00 51.80  ? 191  PRO C CD    1 
ATOM   11111 N  N     . VAL C 2 177  ? 136.973 112.382 173.198 1.00 53.69  ? 192  VAL C N     1 
ATOM   11112 C  CA    . VAL C 2 177  ? 135.706 111.909 173.741 1.00 53.69  ? 192  VAL C CA    1 
ATOM   11113 C  C     . VAL C 2 177  ? 135.941 110.808 174.769 1.00 53.69  ? 192  VAL C C     1 
ATOM   11114 O  O     . VAL C 2 177  ? 137.038 110.670 175.309 1.00 53.69  ? 192  VAL C O     1 
ATOM   11115 C  CB    . VAL C 2 177  ? 134.772 111.411 172.625 1.00 53.69  ? 192  VAL C CB    1 
ATOM   11116 C  CG1   . VAL C 2 177  ? 135.386 110.217 171.913 1.00 53.69  ? 192  VAL C CG1   1 
ATOM   11117 C  CG2   . VAL C 2 177  ? 133.408 111.053 173.196 1.00 53.69  ? 192  VAL C CG2   1 
ATOM   11118 N  N     . ARG C 2 189  ? 138.439 107.933 171.399 1.00 58.53  ? 204  ARG C N     1 
ATOM   11119 C  CA    . ARG C 2 189  ? 138.444 108.479 170.048 1.00 58.53  ? 204  ARG C CA    1 
ATOM   11120 C  C     . ARG C 2 189  ? 138.653 109.987 170.057 1.00 58.53  ? 204  ARG C C     1 
ATOM   11121 O  O     . ARG C 2 189  ? 138.929 110.580 171.099 1.00 58.53  ? 204  ARG C O     1 
ATOM   11122 C  CB    . ARG C 2 189  ? 137.138 108.147 169.325 1.00 58.53  ? 204  ARG C CB    1 
ATOM   11123 C  CG    . ARG C 2 189  ? 136.949 106.677 169.011 1.00 58.53  ? 204  ARG C CG    1 
ATOM   11124 C  CD    . ARG C 2 189  ? 135.780 106.486 168.063 1.00 58.53  ? 204  ARG C CD    1 
ATOM   11125 N  NE    . ARG C 2 189  ? 135.953 107.264 166.842 1.00 58.53  ? 204  ARG C NE    1 
ATOM   11126 C  CZ    . ARG C 2 189  ? 135.044 107.368 165.883 1.00 58.53  ? 204  ARG C CZ    1 
ATOM   11127 N  NH1   . ARG C 2 189  ? 133.873 106.758 165.971 1.00 58.53  ? 204  ARG C NH1   1 
ATOM   11128 N  NH2   . ARG C 2 189  ? 135.315 108.104 164.809 1.00 58.53  ? 204  ARG C NH2   1 
ATOM   11129 N  N     . VAL C 2 190  ? 138.511 110.601 168.887 1.00 53.06  ? 205  VAL C N     1 
ATOM   11130 C  CA    . VAL C 2 190  ? 138.632 112.044 168.724 1.00 53.06  ? 205  VAL C CA    1 
ATOM   11131 C  C     . VAL C 2 190  ? 137.252 112.598 168.411 1.00 53.06  ? 205  VAL C C     1 
ATOM   11132 O  O     . VAL C 2 190  ? 136.562 112.095 167.516 1.00 53.06  ? 205  VAL C O     1 
ATOM   11133 C  CB    . VAL C 2 190  ? 139.632 112.407 167.613 1.00 53.06  ? 205  VAL C CB    1 
ATOM   11134 C  CG1   . VAL C 2 190  ? 140.112 113.840 167.780 1.00 53.06  ? 205  VAL C CG1   1 
ATOM   11135 C  CG2   . VAL C 2 190  ? 140.798 111.434 167.604 1.00 53.06  ? 205  VAL C CG2   1 
ATOM   11136 N  N     . GLY C 2 191  ? 136.850 113.627 169.145 1.00 51.80  ? 206  GLY C N     1 
ATOM   11137 C  CA    . GLY C 2 191  ? 135.560 114.274 168.953 1.00 51.80  ? 206  GLY C CA    1 
ATOM   11138 C  C     . GLY C 2 191  ? 135.755 115.681 168.419 1.00 51.80  ? 206  GLY C C     1 
ATOM   11139 O  O     . GLY C 2 191  ? 136.697 116.376 168.807 1.00 51.80  ? 206  GLY C O     1 
ATOM   11140 N  N     . GLU C 2 192  ? 134.858 116.094 167.531 1.00 46.95  ? 207  GLU C N     1 
ATOM   11141 C  CA    . GLU C 2 192  ? 134.925 117.403 166.903 1.00 46.95  ? 207  GLU C CA    1 
ATOM   11142 C  C     . GLU C 2 192  ? 133.676 118.195 167.253 1.00 46.95  ? 207  GLU C C     1 
ATOM   11143 O  O     . GLU C 2 192  ? 132.556 117.698 167.095 1.00 46.95  ? 207  GLU C O     1 
ATOM   11144 C  CB    . GLU C 2 192  ? 135.062 117.275 165.387 1.00 46.95  ? 207  GLU C CB    1 
ATOM   11145 C  CG    . GLU C 2 192  ? 136.329 116.578 164.948 1.00 46.95  ? 207  GLU C CG    1 
ATOM   11146 C  CD    . GLU C 2 192  ? 136.328 116.268 163.471 1.00 46.95  ? 207  GLU C CD    1 
ATOM   11147 O  OE1   . GLU C 2 192  ? 135.285 116.489 162.821 1.00 46.95  ? 207  GLU C OE1   1 
ATOM   11148 O  OE2   . GLU C 2 192  ? 137.367 115.801 162.962 1.00 46.95  ? 207  GLU C OE2   1 
ATOM   11149 N  N     . LYS C 2 193  ? 133.873 119.421 167.726 1.00 49.35  ? 208  LYS C N     1 
ATOM   11150 C  CA    . LYS C 2 193  ? 132.781 120.342 167.988 1.00 49.35  ? 208  LYS C CA    1 
ATOM   11151 C  C     . LYS C 2 193  ? 133.085 121.669 167.310 1.00 49.35  ? 208  LYS C C     1 
ATOM   11152 O  O     . LYS C 2 193  ? 134.244 122.076 167.197 1.00 49.35  ? 208  LYS C O     1 
ATOM   11153 C  CB    . LYS C 2 193  ? 132.556 120.553 169.492 1.00 49.35  ? 208  LYS C CB    1 
ATOM   11154 C  CG    . LYS C 2 193  ? 133.582 121.451 170.159 1.00 49.35  ? 208  LYS C CG    1 
ATOM   11155 C  CD    . LYS C 2 193  ? 133.219 121.719 171.606 1.00 49.35  ? 208  LYS C CD    1 
ATOM   11156 C  CE    . LYS C 2 193  ? 134.073 122.832 172.188 1.00 49.35  ? 208  LYS C CE    1 
ATOM   11157 N  NZ    . LYS C 2 193  ? 135.525 122.511 172.126 1.00 49.35  ? 208  LYS C NZ    1 
ATOM   11158 N  N     . THR C 2 194  ? 132.032 122.330 166.839 1.00 44.88  ? 209  THR C N     1 
ATOM   11159 C  CA    . THR C 2 194  ? 132.160 123.625 166.181 1.00 44.88  ? 209  THR C CA    1 
ATOM   11160 C  C     . THR C 2 194  ? 132.011 124.712 167.236 1.00 44.88  ? 209  THR C C     1 
ATOM   11161 O  O     . THR C 2 194  ? 130.903 124.986 167.705 1.00 44.88  ? 209  THR C O     1 
ATOM   11162 C  CB    . THR C 2 194  ? 131.116 123.785 165.080 1.00 44.88  ? 209  THR C CB    1 
ATOM   11163 O  OG1   . THR C 2 194  ? 131.055 122.586 164.299 1.00 44.88  ? 209  THR C OG1   1 
ATOM   11164 C  CG2   . THR C 2 194  ? 131.479 124.951 164.176 1.00 44.88  ? 209  THR C CG2   1 
ATOM   11165 N  N     . GLU C 2 195  ? 133.125 125.325 167.616 1.00 41.98  ? 210  GLU C N     1 
ATOM   11166 C  CA    . GLU C 2 195  ? 133.142 126.348 168.649 1.00 41.98  ? 210  GLU C CA    1 
ATOM   11167 C  C     . GLU C 2 195  ? 133.293 127.719 168.010 1.00 41.98  ? 210  GLU C C     1 
ATOM   11168 O  O     . GLU C 2 195  ? 134.230 127.948 167.240 1.00 41.98  ? 210  GLU C O     1 
ATOM   11169 C  CB    . GLU C 2 195  ? 134.275 126.103 169.643 1.00 41.98  ? 210  GLU C CB    1 
ATOM   11170 C  CG    . GLU C 2 195  ? 134.601 127.307 170.498 1.00 41.98  ? 210  GLU C CG    1 
ATOM   11171 C  CD    . GLU C 2 195  ? 135.606 126.991 171.578 1.00 41.98  ? 210  GLU C CD    1 
ATOM   11172 O  OE1   . GLU C 2 195  ? 135.516 125.891 172.163 1.00 41.98  ? 210  GLU C OE1   1 
ATOM   11173 O  OE2   . GLU C 2 195  ? 136.488 127.836 171.838 1.00 41.98  ? 210  GLU C OE2   1 
ATOM   11174 N  N     . ALA C 2 196  ? 132.369 128.620 168.327 1.00 30.70  ? 211  ALA C N     1 
ATOM   11175 C  CA    . ALA C 2 196  ? 132.439 130.011 167.901 1.00 30.70  ? 211  ALA C CA    1 
ATOM   11176 C  C     . ALA C 2 196  ? 133.015 130.814 169.057 1.00 30.70  ? 211  ALA C C     1 
ATOM   11177 O  O     . ALA C 2 196  ? 132.349 131.009 170.078 1.00 30.70  ? 211  ALA C O     1 
ATOM   11178 C  CB    . ALA C 2 196  ? 131.064 130.533 167.497 1.00 30.70  ? 211  ALA C CB    1 
ATOM   11179 N  N     . SER C 2 197  ? 134.250 131.274 168.900 1.00 31.63  ? 212  SER C N     1 
ATOM   11180 C  CA    . SER C 2 197  ? 134.988 131.906 169.982 1.00 31.63  ? 212  SER C CA    1 
ATOM   11181 C  C     . SER C 2 197  ? 135.064 133.406 169.755 1.00 31.63  ? 212  SER C C     1 
ATOM   11182 O  O     . SER C 2 197  ? 135.371 133.857 168.649 1.00 31.63  ? 212  SER C O     1 
ATOM   11183 C  CB    . SER C 2 197  ? 136.400 131.332 170.092 1.00 31.63  ? 212  SER C CB    1 
ATOM   11184 O  OG    . SER C 2 197  ? 137.281 131.997 169.204 1.00 31.63  ? 212  SER C OG    1 
ATOM   11185 N  N     . LEU C 2 198  ? 134.782 134.168 170.804 1.00 35.79  ? 213  LEU C N     1 
ATOM   11186 C  CA    . LEU C 2 198  ? 135.076 135.593 170.851 1.00 35.79  ? 213  LEU C CA    1 
ATOM   11187 C  C     . LEU C 2 198  ? 136.136 135.811 171.917 1.00 35.79  ? 213  LEU C C     1 
ATOM   11188 O  O     . LEU C 2 198  ? 135.913 135.496 173.090 1.00 35.79  ? 213  LEU C O     1 
ATOM   11189 C  CB    . LEU C 2 198  ? 133.827 136.415 171.167 1.00 35.79  ? 213  LEU C CB    1 
ATOM   11190 C  CG    . LEU C 2 198  ? 134.107 137.892 171.464 1.00 35.79  ? 213  LEU C CG    1 
ATOM   11191 C  CD1   . LEU C 2 198  ? 134.208 138.711 170.182 1.00 35.79  ? 213  LEU C CD1   1 
ATOM   11192 C  CD2   . LEU C 2 198  ? 133.068 138.472 172.408 1.00 35.79  ? 213  LEU C CD2   1 
ATOM   11193 N  N     . VAL C 2 199  ? 137.282 136.345 171.513 1.00 40.98  ? 214  VAL C N     1 
ATOM   11194 C  CA    . VAL C 2 199  ? 138.373 136.654 172.426 1.00 40.98  ? 214  VAL C CA    1 
ATOM   11195 C  C     . VAL C 2 199  ? 138.512 138.166 172.470 1.00 40.98  ? 214  VAL C C     1 
ATOM   11196 O  O     . VAL C 2 199  ? 138.799 138.801 171.448 1.00 40.98  ? 214  VAL C O     1 
ATOM   11197 C  CB    . VAL C 2 199  ? 139.683 135.980 171.995 1.00 40.98  ? 214  VAL C CB    1 
ATOM   11198 C  CG1   . VAL C 2 199  ? 140.840 136.489 172.830 1.00 40.98  ? 214  VAL C CG1   1 
ATOM   11199 C  CG2   . VAL C 2 199  ? 139.559 134.469 172.117 1.00 40.98  ? 214  VAL C CG2   1 
ATOM   11200 N  N     . TRP C 2 200  ? 138.308 138.742 173.649 1.00 46.35  ? 215  TRP C N     1 
ATOM   11201 C  CA    . TRP C 2 200  ? 138.252 140.187 173.819 1.00 46.35  ? 215  TRP C CA    1 
ATOM   11202 C  C     . TRP C 2 200  ? 139.509 140.652 174.540 1.00 46.35  ? 215  TRP C C     1 
ATOM   11203 O  O     . TRP C 2 200  ? 139.818 140.166 175.633 1.00 46.35  ? 215  TRP C O     1 
ATOM   11204 C  CB    . TRP C 2 200  ? 136.992 140.589 174.586 1.00 46.35  ? 215  TRP C CB    1 
ATOM   11205 C  CG    . TRP C 2 200  ? 136.772 142.068 174.660 1.00 46.35  ? 215  TRP C CG    1 
ATOM   11206 C  CD1   . TRP C 2 200  ? 136.677 142.825 175.789 1.00 46.35  ? 215  TRP C CD1   1 
ATOM   11207 C  CD2   . TRP C 2 200  ? 136.628 142.974 173.557 1.00 46.35  ? 215  TRP C CD2   1 
ATOM   11208 N  NE1   . TRP C 2 200  ? 136.480 144.144 175.460 1.00 46.35  ? 215  TRP C NE1   1 
ATOM   11209 C  CE2   . TRP C 2 200  ? 136.446 144.261 174.096 1.00 46.35  ? 215  TRP C CE2   1 
ATOM   11210 C  CE3   . TRP C 2 200  ? 136.632 142.819 172.167 1.00 46.35  ? 215  TRP C CE3   1 
ATOM   11211 C  CZ2   . TRP C 2 200  ? 136.271 145.387 173.295 1.00 46.35  ? 215  TRP C CZ2   1 
ATOM   11212 C  CZ3   . TRP C 2 200  ? 136.460 143.938 171.376 1.00 46.35  ? 215  TRP C CZ3   1 
ATOM   11213 C  CH2   . TRP C 2 200  ? 136.283 145.205 171.941 1.00 46.35  ? 215  TRP C CH2   1 
ATOM   11214 N  N     . PHE C 2 201  ? 140.229 141.589 173.925 1.00 52.64  ? 216  PHE C N     1 
ATOM   11215 C  CA    . PHE C 2 201  ? 141.488 142.096 174.466 1.00 52.64  ? 216  PHE C CA    1 
ATOM   11216 C  C     . PHE C 2 201  ? 141.208 143.412 175.186 1.00 52.64  ? 216  PHE C C     1 
ATOM   11217 O  O     . PHE C 2 201  ? 141.460 144.503 174.676 1.00 52.64  ? 216  PHE C O     1 
ATOM   11218 C  CB    . PHE C 2 201  ? 142.522 142.265 173.355 1.00 52.64  ? 216  PHE C CB    1 
ATOM   11219 C  CG    . PHE C 2 201  ? 142.882 140.983 172.654 1.00 52.64  ? 216  PHE C CG    1 
ATOM   11220 C  CD1   . PHE C 2 201  ? 142.092 140.491 171.628 1.00 52.64  ? 216  PHE C CD1   1 
ATOM   11221 C  CD2   . PHE C 2 201  ? 144.020 140.280 173.010 1.00 52.64  ? 216  PHE C CD2   1 
ATOM   11222 C  CE1   . PHE C 2 201  ? 142.422 139.317 170.981 1.00 52.64  ? 216  PHE C CE1   1 
ATOM   11223 C  CE2   . PHE C 2 201  ? 144.355 139.105 172.364 1.00 52.64  ? 216  PHE C CE2   1 
ATOM   11224 C  CZ    . PHE C 2 201  ? 143.555 138.625 171.349 1.00 52.64  ? 216  PHE C CZ    1 
ATOM   11225 N  N     . THR C 2 202  ? 140.676 143.295 176.403 1.00 55.49  ? 217  THR C N     1 
ATOM   11226 C  CA    . THR C 2 202  ? 140.319 144.452 177.206 1.00 55.49  ? 217  THR C CA    1 
ATOM   11227 C  C     . THR C 2 202  ? 141.395 144.750 178.243 1.00 55.49  ? 217  THR C C     1 
ATOM   11228 O  O     . THR C 2 202  ? 142.070 143.837 178.729 1.00 55.49  ? 217  THR C O     1 
ATOM   11229 C  CB    . THR C 2 202  ? 138.985 144.222 177.923 1.00 55.49  ? 217  THR C CB    1 
ATOM   11230 O  OG1   . THR C 2 202  ? 138.803 145.221 178.932 1.00 55.49  ? 217  THR C OG1   1 
ATOM   11231 C  CG2   . THR C 2 202  ? 138.960 142.850 178.570 1.00 55.49  ? 217  THR C CG2   1 
ATOM   11232 N  N     . PRO C 2 203  ? 141.584 146.022 178.593 1.00 59.61  ? 218  PRO C N     1 
ATOM   11233 C  CA    . PRO C 2 203  ? 142.510 146.358 179.678 1.00 59.61  ? 218  PRO C CA    1 
ATOM   11234 C  C     . PRO C 2 203  ? 142.056 145.767 181.005 1.00 59.61  ? 218  PRO C C     1 
ATOM   11235 O  O     . PRO C 2 203  ? 140.915 145.328 181.169 1.00 59.61  ? 218  PRO C O     1 
ATOM   11236 C  CB    . PRO C 2 203  ? 142.484 147.891 179.708 1.00 59.61  ? 218  PRO C CB    1 
ATOM   11237 C  CG    . PRO C 2 203  ? 142.081 148.281 178.326 1.00 59.61  ? 218  PRO C CG    1 
ATOM   11238 C  CD    . PRO C 2 203  ? 141.122 147.220 177.870 1.00 59.61  ? 218  PRO C CD    1 
ATOM   11239 N  N     . THR C 2 204  ? 142.982 145.761 181.966 1.00 62.40  ? 219  THR C N     1 
ATOM   11240 C  CA    . THR C 2 204  ? 142.740 145.077 183.233 1.00 62.40  ? 219  THR C CA    1 
ATOM   11241 C  C     . THR C 2 204  ? 141.669 145.775 184.063 1.00 62.40  ? 219  THR C C     1 
ATOM   11242 O  O     . THR C 2 204  ? 140.855 145.110 184.715 1.00 62.40  ? 219  THR C O     1 
ATOM   11243 C  CB    . THR C 2 204  ? 144.042 144.975 184.026 1.00 62.40  ? 219  THR C CB    1 
ATOM   11244 O  OG1   . THR C 2 204  ? 144.532 146.290 184.312 1.00 62.40  ? 219  THR C OG1   1 
ATOM   11245 C  CG2   . THR C 2 204  ? 145.090 144.216 183.229 1.00 62.40  ? 219  THR C CG2   1 
ATOM   11246 N  N     . ARG C 2 205  ? 141.657 147.110 184.062 1.00 66.57  ? 220  ARG C N     1 
ATOM   11247 C  CA    . ARG C 2 205  ? 140.743 147.838 184.938 1.00 66.57  ? 220  ARG C CA    1 
ATOM   11248 C  C     . ARG C 2 205  ? 139.289 147.626 184.534 1.00 66.57  ? 220  ARG C C     1 
ATOM   11249 O  O     . ARG C 2 205  ? 138.402 147.572 185.394 1.00 66.57  ? 220  ARG C O     1 
ATOM   11250 C  CB    . ARG C 2 205  ? 141.090 149.328 184.948 1.00 66.57  ? 220  ARG C CB    1 
ATOM   11251 C  CG    . ARG C 2 205  ? 140.940 150.034 183.609 1.00 66.57  ? 220  ARG C CG    1 
ATOM   11252 C  CD    . ARG C 2 205  ? 140.858 151.541 183.798 1.00 66.57  ? 220  ARG C CD    1 
ATOM   11253 N  NE    . ARG C 2 205  ? 140.540 152.241 182.560 1.00 66.57  ? 220  ARG C NE    1 
ATOM   11254 C  CZ    . ARG C 2 205  ? 141.422 152.905 181.826 1.00 66.57  ? 220  ARG C CZ    1 
ATOM   11255 N  NH1   . ARG C 2 205  ? 142.695 152.983 182.177 1.00 66.57  ? 220  ARG C NH1   1 
ATOM   11256 N  NH2   . ARG C 2 205  ? 141.016 153.511 180.714 1.00 66.57  ? 220  ARG C NH2   1 
ATOM   11257 N  N     . THR C 2 206  ? 139.022 147.504 183.235 1.00 58.20  ? 221  THR C N     1 
ATOM   11258 C  CA    . THR C 2 206  ? 137.673 147.309 182.726 1.00 58.20  ? 221  THR C CA    1 
ATOM   11259 C  C     . THR C 2 206  ? 137.364 145.842 182.450 1.00 58.20  ? 221  THR C C     1 
ATOM   11260 O  O     . THR C 2 206  ? 136.439 145.544 181.688 1.00 58.20  ? 221  THR C O     1 
ATOM   11261 C  CB    . THR C 2 206  ? 137.463 148.137 181.459 1.00 58.20  ? 221  THR C CB    1 
ATOM   11262 O  OG1   . THR C 2 206  ? 138.325 147.653 180.423 1.00 58.20  ? 221  THR C OG1   1 
ATOM   11263 C  CG2   . THR C 2 206  ? 137.779 149.599 181.723 1.00 58.20  ? 221  THR C CG2   1 
ATOM   11264 N  N     . SER C 2 207  ? 138.122 144.923 183.051 1.00 56.75  ? 222  SER C N     1 
ATOM   11265 C  CA    . SER C 2 207  ? 137.946 143.504 182.760 1.00 56.75  ? 222  SER C CA    1 
ATOM   11266 C  C     . SER C 2 207  ? 136.560 143.020 183.165 1.00 56.75  ? 222  SER C C     1 
ATOM   11267 O  O     . SER C 2 207  ? 135.841 142.418 182.360 1.00 56.75  ? 222  SER C O     1 
ATOM   11268 C  CB    . SER C 2 207  ? 139.026 142.688 183.469 1.00 56.75  ? 222  SER C CB    1 
ATOM   11269 O  OG    . SER C 2 207  ? 138.923 142.819 184.876 1.00 56.75  ? 222  SER C OG    1 
ATOM   11270 N  N     . SER C 2 208  ? 136.163 143.279 184.412 1.00 51.13  ? 223  SER C N     1 
ATOM   11271 C  CA    . SER C 2 208  ? 134.868 142.796 184.879 1.00 51.13  ? 223  SER C CA    1 
ATOM   11272 C  C     . SER C 2 208  ? 133.714 143.546 184.228 1.00 51.13  ? 223  SER C C     1 
ATOM   11273 O  O     . SER C 2 208  ? 132.652 142.960 183.993 1.00 51.13  ? 223  SER C O     1 
ATOM   11274 C  CB    . SER C 2 208  ? 134.781 142.905 186.400 1.00 51.13  ? 223  SER C CB    1 
ATOM   11275 O  OG    . SER C 2 208  ? 133.569 142.344 186.876 1.00 51.13  ? 223  SER C OG    1 
ATOM   11276 N  N     . GLN C 2 209  ? 133.901 144.833 183.926 1.00 53.97  ? 224  GLN C N     1 
ATOM   11277 C  CA    . GLN C 2 209  ? 132.856 145.593 183.245 1.00 53.97  ? 224  GLN C CA    1 
ATOM   11278 C  C     . GLN C 2 209  ? 132.560 145.003 181.873 1.00 53.97  ? 224  GLN C C     1 
ATOM   11279 O  O     . GLN C 2 209  ? 131.403 144.713 181.544 1.00 53.97  ? 224  GLN C O     1 
ATOM   11280 C  CB    . GLN C 2 209  ? 133.266 147.061 183.121 1.00 53.97  ? 224  GLN C CB    1 
ATOM   11281 C  CG    . GLN C 2 209  ? 133.238 147.840 184.427 1.00 53.97  ? 224  GLN C CG    1 
ATOM   11282 C  CD    . GLN C 2 209  ? 134.373 147.470 185.363 1.00 53.97  ? 224  GLN C CD    1 
ATOM   11283 O  OE1   . GLN C 2 209  ? 135.305 146.762 184.980 1.00 53.97  ? 224  GLN C OE1   1 
ATOM   11284 N  NE2   . GLN C 2 209  ? 134.298 147.948 186.598 1.00 53.97  ? 224  GLN C NE2   1 
ATOM   11285 N  N     . TRP C 2 210  ? 133.601 144.810 181.059 1.00 45.52  ? 225  TRP C N     1 
ATOM   11286 C  CA    . TRP C 2 210  ? 133.402 144.196 179.753 1.00 45.52  ? 225  TRP C CA    1 
ATOM   11287 C  C     . TRP C 2 210  ? 132.933 142.756 179.878 1.00 45.52  ? 225  TRP C C     1 
ATOM   11288 O  O     . TRP C 2 210  ? 132.177 142.283 179.027 1.00 45.52  ? 225  TRP C O     1 
ATOM   11289 C  CB    . TRP C 2 210  ? 134.686 144.257 178.931 1.00 45.52  ? 225  TRP C CB    1 
ATOM   11290 C  CG    . TRP C 2 210  ? 134.988 145.603 178.364 1.00 45.52  ? 225  TRP C CG    1 
ATOM   11291 C  CD1   . TRP C 2 210  ? 135.797 146.554 178.905 1.00 45.52  ? 225  TRP C CD1   1 
ATOM   11292 C  CD2   . TRP C 2 210  ? 134.499 146.144 177.133 1.00 45.52  ? 225  TRP C CD2   1 
ATOM   11293 N  NE1   . TRP C 2 210  ? 135.840 147.658 178.091 1.00 45.52  ? 225  TRP C NE1   1 
ATOM   11294 C  CE2   . TRP C 2 210  ? 135.051 147.431 176.995 1.00 45.52  ? 225  TRP C CE2   1 
ATOM   11295 C  CE3   . TRP C 2 210  ? 133.647 145.666 176.135 1.00 45.52  ? 225  TRP C CE3   1 
ATOM   11296 C  CZ2   . TRP C 2 210  ? 134.778 148.247 175.901 1.00 45.52  ? 225  TRP C CZ2   1 
ATOM   11297 C  CZ3   . TRP C 2 210  ? 133.377 146.476 175.050 1.00 45.52  ? 225  TRP C CZ3   1 
ATOM   11298 C  CH2   . TRP C 2 210  ? 133.941 147.752 174.941 1.00 45.52  ? 225  TRP C CH2   1 
ATOM   11299 N  N     . LEU C 2 211  ? 133.362 142.045 180.922 1.00 45.33  ? 226  LEU C N     1 
ATOM   11300 C  CA    . LEU C 2 211  ? 132.902 140.675 181.114 1.00 45.33  ? 226  LEU C CA    1 
ATOM   11301 C  C     . LEU C 2 211  ? 131.399 140.631 181.350 1.00 45.33  ? 226  LEU C C     1 
ATOM   11302 O  O     . LEU C 2 211  ? 130.690 139.816 180.752 1.00 45.33  ? 226  LEU C O     1 
ATOM   11303 C  CB    . LEU C 2 211  ? 133.650 140.022 182.277 1.00 45.33  ? 226  LEU C CB    1 
ATOM   11304 C  CG    . LEU C 2 211  ? 133.229 138.587 182.602 1.00 45.33  ? 226  LEU C CG    1 
ATOM   11305 C  CD1   . LEU C 2 211  ? 133.346 137.706 181.372 1.00 45.33  ? 226  LEU C CD1   1 
ATOM   11306 C  CD2   . LEU C 2 211  ? 134.064 138.032 183.741 1.00 45.33  ? 226  LEU C CD2   1 
ATOM   11307 N  N     . ASP C 2 212  ? 130.888 141.514 182.210 1.00 45.53  ? 227  ASP C N     1 
ATOM   11308 C  CA    . ASP C 2 212  ? 129.450 141.549 182.456 1.00 45.53  ? 227  ASP C CA    1 
ATOM   11309 C  C     . ASP C 2 212  ? 128.693 142.048 181.231 1.00 45.53  ? 227  ASP C C     1 
ATOM   11310 O  O     . ASP C 2 212  ? 127.592 141.566 180.933 1.00 45.53  ? 227  ASP C O     1 
ATOM   11311 C  CB    . ASP C 2 212  ? 129.142 142.423 183.670 1.00 45.53  ? 227  ASP C CB    1 
ATOM   11312 C  CG    . ASP C 2 212  ? 127.666 142.439 184.014 1.00 45.53  ? 227  ASP C CG    1 
ATOM   11313 O  OD1   . ASP C 2 212  ? 127.124 141.367 184.357 1.00 45.53  ? 227  ASP C OD1   1 
ATOM   11314 O  OD2   . ASP C 2 212  ? 127.049 143.522 183.940 1.00 45.53  ? 227  ASP C OD2   1 
ATOM   11315 N  N     . PHE C 2 213  ? 129.266 143.018 180.515 1.00 39.58  ? 228  PHE C N     1 
ATOM   11316 C  CA    . PHE C 2 213  ? 128.652 143.498 179.283 1.00 39.58  ? 228  PHE C CA    1 
ATOM   11317 C  C     . PHE C 2 213  ? 128.499 142.369 178.274 1.00 39.58  ? 228  PHE C C     1 
ATOM   11318 O  O     . PHE C 2 213  ? 127.417 142.164 177.711 1.00 39.58  ? 228  PHE C O     1 
ATOM   11319 C  CB    . PHE C 2 213  ? 129.486 144.641 178.705 1.00 39.58  ? 228  PHE C CB    1 
ATOM   11320 C  CG    . PHE C 2 213  ? 129.383 144.780 177.215 1.00 39.58  ? 228  PHE C CG    1 
ATOM   11321 C  CD1   . PHE C 2 213  ? 128.237 145.280 176.627 1.00 39.58  ? 228  PHE C CD1   1 
ATOM   11322 C  CD2   . PHE C 2 213  ? 130.445 144.426 176.404 1.00 39.58  ? 228  PHE C CD2   1 
ATOM   11323 C  CE1   . PHE C 2 213  ? 128.150 145.414 175.256 1.00 39.58  ? 228  PHE C CE1   1 
ATOM   11324 C  CE2   . PHE C 2 213  ? 130.362 144.559 175.034 1.00 39.58  ? 228  PHE C CE2   1 
ATOM   11325 C  CZ    . PHE C 2 213  ? 129.213 145.052 174.460 1.00 39.58  ? 228  PHE C CZ    1 
ATOM   11326 N  N     . TRP C 2 214  ? 129.575 141.614 178.044 1.00 35.02  ? 229  TRP C N     1 
ATOM   11327 C  CA    . TRP C 2 214  ? 129.508 140.490 177.121 1.00 35.02  ? 229  TRP C CA    1 
ATOM   11328 C  C     . TRP C 2 214  ? 128.598 139.391 177.642 1.00 35.02  ? 229  TRP C C     1 
ATOM   11329 O  O     . TRP C 2 214  ? 127.921 138.737 176.850 1.00 35.02  ? 229  TRP C O     1 
ATOM   11330 C  CB    . TRP C 2 214  ? 130.904 139.934 176.855 1.00 35.02  ? 229  TRP C CB    1 
ATOM   11331 C  CG    . TRP C 2 214  ? 131.721 140.775 175.934 1.00 35.02  ? 229  TRP C CG    1 
ATOM   11332 C  CD1   . TRP C 2 214  ? 132.893 141.406 176.225 1.00 35.02  ? 229  TRP C CD1   1 
ATOM   11333 C  CD2   . TRP C 2 214  ? 131.428 141.082 174.567 1.00 35.02  ? 229  TRP C CD2   1 
ATOM   11334 N  NE1   . TRP C 2 214  ? 133.352 142.085 175.123 1.00 35.02  ? 229  TRP C NE1   1 
ATOM   11335 C  CE2   . TRP C 2 214  ? 132.470 141.903 174.092 1.00 35.02  ? 229  TRP C CE2   1 
ATOM   11336 C  CE3   . TRP C 2 214  ? 130.388 140.743 173.698 1.00 35.02  ? 229  TRP C CE3   1 
ATOM   11337 C  CZ2   . TRP C 2 214  ? 132.501 142.388 172.787 1.00 35.02  ? 229  TRP C CZ2   1 
ATOM   11338 C  CZ3   . TRP C 2 214  ? 130.421 141.226 172.405 1.00 35.02  ? 229  TRP C CZ3   1 
ATOM   11339 C  CH2   . TRP C 2 214  ? 131.470 142.039 171.961 1.00 35.02  ? 229  TRP C CH2   1 
ATOM   11340 N  N     . LEU C 2 215  ? 128.554 139.179 178.957 1.00 35.55  ? 230  LEU C N     1 
ATOM   11341 C  CA    . LEU C 2 215  ? 127.652 138.176 179.511 1.00 35.55  ? 230  LEU C CA    1 
ATOM   11342 C  C     . LEU C 2 215  ? 126.202 138.512 179.191 1.00 35.55  ? 230  LEU C C     1 
ATOM   11343 O  O     . LEU C 2 215  ? 125.457 137.674 178.667 1.00 35.55  ? 230  LEU C O     1 
ATOM   11344 C  CB    . LEU C 2 215  ? 127.864 138.066 181.021 1.00 35.55  ? 230  LEU C CB    1 
ATOM   11345 C  CG    . LEU C 2 215  ? 126.928 137.130 181.784 1.00 35.55  ? 230  LEU C CG    1 
ATOM   11346 C  CD1   . LEU C 2 215  ? 127.090 135.702 181.299 1.00 35.55  ? 230  LEU C CD1   1 
ATOM   11347 C  CD2   . LEU C 2 215  ? 127.185 137.226 183.278 1.00 35.55  ? 230  LEU C CD2   1 
ATOM   11348 N  N     . ARG C 2 216  ? 125.790 139.751 179.474 1.00 43.33  ? 231  ARG C N     1 
ATOM   11349 C  CA    . ARG C 2 216  ? 124.404 140.125 179.213 1.00 43.33  ? 231  ARG C CA    1 
ATOM   11350 C  C     . ARG C 2 216  ? 124.116 140.178 177.717 1.00 43.33  ? 231  ARG C C     1 
ATOM   11351 O  O     . ARG C 2 216  ? 123.027 139.789 177.281 1.00 43.33  ? 231  ARG C O     1 
ATOM   11352 C  CB    . ARG C 2 216  ? 124.065 141.456 179.887 1.00 43.33  ? 231  ARG C CB    1 
ATOM   11353 C  CG    . ARG C 2 216  ? 124.677 142.689 179.251 1.00 43.33  ? 231  ARG C CG    1 
ATOM   11354 C  CD    . ARG C 2 216  ? 123.900 143.938 179.637 1.00 43.33  ? 231  ARG C CD    1 
ATOM   11355 N  NE    . ARG C 2 216  ? 124.485 145.145 179.065 1.00 43.33  ? 231  ARG C NE    1 
ATOM   11356 C  CZ    . ARG C 2 216  ? 125.347 145.928 179.698 1.00 43.33  ? 231  ARG C CZ    1 
ATOM   11357 N  NH1   . ARG C 2 216  ? 125.737 145.670 180.935 1.00 43.33  ? 231  ARG C NH1   1 
ATOM   11358 N  NH2   . ARG C 2 216  ? 125.830 146.998 179.073 1.00 43.33  ? 231  ARG C NH2   1 
ATOM   11359 N  N     . HIS C 2 217  ? 125.081 140.627 176.907 1.00 37.99  ? 232  HIS C N     1 
ATOM   11360 C  CA    . HIS C 2 217  ? 124.859 140.678 175.465 1.00 37.99  ? 232  HIS C CA    1 
ATOM   11361 C  C     . HIS C 2 217  ? 124.740 139.282 174.866 1.00 37.99  ? 232  HIS C C     1 
ATOM   11362 O  O     . HIS C 2 217  ? 123.893 139.047 174.000 1.00 37.99  ? 232  HIS C O     1 
ATOM   11363 C  CB    . HIS C 2 217  ? 125.974 141.467 174.786 1.00 37.99  ? 232  HIS C CB    1 
ATOM   11364 C  CG    . HIS C 2 217  ? 125.644 142.911 174.582 1.00 37.99  ? 232  HIS C CG    1 
ATOM   11365 N  ND1   . HIS C 2 217  ? 125.748 143.533 173.357 1.00 37.99  ? 232  HIS C ND1   1 
ATOM   11366 C  CD2   . HIS C 2 217  ? 125.192 143.852 175.444 1.00 37.99  ? 232  HIS C CD2   1 
ATOM   11367 C  CE1   . HIS C 2 217  ? 125.383 144.797 173.474 1.00 37.99  ? 232  HIS C CE1   1 
ATOM   11368 N  NE2   . HIS C 2 217  ? 125.041 145.016 174.731 1.00 37.99  ? 232  HIS C NE2   1 
ATOM   11369 N  N     . ARG C 2 218  ? 125.572 138.340 175.314 1.00 30.63  ? 233  ARG C N     1 
ATOM   11370 C  CA    . ARG C 2 218  ? 125.471 136.972 174.820 1.00 30.63  ? 233  ARG C CA    1 
ATOM   11371 C  C     . ARG C 2 218  ? 124.186 136.312 175.296 1.00 30.63  ? 233  ARG C C     1 
ATOM   11372 O  O     . ARG C 2 218  ? 123.576 135.530 174.559 1.00 30.63  ? 233  ARG C O     1 
ATOM   11373 C  CB    . ARG C 2 218  ? 126.689 136.160 175.257 1.00 30.63  ? 233  ARG C CB    1 
ATOM   11374 C  CG    . ARG C 2 218  ? 127.999 136.603 174.622 1.00 30.63  ? 233  ARG C CG    1 
ATOM   11375 C  CD    . ARG C 2 218  ? 127.853 136.739 173.122 1.00 30.63  ? 233  ARG C CD    1 
ATOM   11376 N  NE    . ARG C 2 218  ? 127.358 135.509 172.520 1.00 30.63  ? 233  ARG C NE    1 
ATOM   11377 C  CZ    . ARG C 2 218  ? 126.802 135.435 171.320 1.00 30.63  ? 233  ARG C CZ    1 
ATOM   11378 N  NH1   . ARG C 2 218  ? 126.653 136.508 170.561 1.00 30.63  ? 233  ARG C NH1   1 
ATOM   11379 N  NH2   . ARG C 2 218  ? 126.376 134.257 170.874 1.00 30.63  ? 233  ARG C NH2   1 
ATOM   11380 N  N     . LEU C 2 219  ? 123.753 136.615 176.522 1.00 32.22  ? 234  LEU C N     1 
ATOM   11381 C  CA    . LEU C 2 219  ? 122.480 136.078 176.988 1.00 32.22  ? 234  LEU C CA    1 
ATOM   11382 C  C     . LEU C 2 219  ? 121.322 136.622 176.159 1.00 32.22  ? 234  LEU C C     1 
ATOM   11383 O  O     . LEU C 2 219  ? 120.405 135.876 175.797 1.00 32.22  ? 234  LEU C O     1 
ATOM   11384 C  CB    . LEU C 2 219  ? 122.291 136.391 178.471 1.00 32.22  ? 234  LEU C CB    1 
ATOM   11385 C  CG    . LEU C 2 219  ? 121.186 135.604 179.175 1.00 32.22  ? 234  LEU C CG    1 
ATOM   11386 C  CD1   . LEU C 2 219  ? 121.309 134.121 178.865 1.00 32.22  ? 234  LEU C CD1   1 
ATOM   11387 C  CD2   . LEU C 2 219  ? 121.236 135.841 180.674 1.00 32.22  ? 234  LEU C CD2   1 
ATOM   11388 N  N     . LEU C 2 220  ? 121.358 137.918 175.832 1.00 35.87  ? 235  LEU C N     1 
ATOM   11389 C  CA    . LEU C 2 220  ? 120.337 138.494 174.961 1.00 35.87  ? 235  LEU C CA    1 
ATOM   11390 C  C     . LEU C 2 220  ? 120.377 137.868 173.574 1.00 35.87  ? 235  LEU C C     1 
ATOM   11391 O  O     . LEU C 2 220  ? 119.330 137.596 172.977 1.00 35.87  ? 235  LEU C O     1 
ATOM   11392 C  CB    . LEU C 2 220  ? 120.516 140.008 174.863 1.00 35.87  ? 235  LEU C CB    1 
ATOM   11393 C  CG    . LEU C 2 220  ? 120.229 140.822 176.124 1.00 35.87  ? 235  LEU C CG    1 
ATOM   11394 C  CD1   . LEU C 2 220  ? 120.426 142.303 175.853 1.00 35.87  ? 235  LEU C CD1   1 
ATOM   11395 C  CD2   . LEU C 2 220  ? 118.824 140.549 176.637 1.00 35.87  ? 235  LEU C CD2   1 
ATOM   11396 N  N     . TRP C 2 221  ? 121.579 137.647 173.039 1.00 29.42  ? 236  TRP C N     1 
ATOM   11397 C  CA    . TRP C 2 221  ? 121.710 137.033 171.723 1.00 29.42  ? 236  TRP C CA    1 
ATOM   11398 C  C     . TRP C 2 221  ? 121.126 135.627 171.709 1.00 29.42  ? 236  TRP C C     1 
ATOM   11399 O  O     . TRP C 2 221  ? 120.425 135.246 170.765 1.00 29.42  ? 236  TRP C O     1 
ATOM   11400 C  CB    . TRP C 2 221  ? 123.182 137.008 171.311 1.00 29.42  ? 236  TRP C CB    1 
ATOM   11401 C  CG    . TRP C 2 221  ? 123.432 136.498 169.926 1.00 29.42  ? 236  TRP C CG    1 
ATOM   11402 C  CD1   . TRP C 2 221  ? 123.676 137.243 168.814 1.00 29.42  ? 236  TRP C CD1   1 
ATOM   11403 C  CD2   . TRP C 2 221  ? 123.473 135.127 169.507 1.00 29.42  ? 236  TRP C CD2   1 
ATOM   11404 N  NE1   . TRP C 2 221  ? 123.862 136.426 167.727 1.00 29.42  ? 236  TRP C NE1   1 
ATOM   11405 C  CE2   . TRP C 2 221  ? 123.742 135.121 168.127 1.00 29.42  ? 236  TRP C CE2   1 
ATOM   11406 C  CE3   . TRP C 2 221  ? 123.307 133.905 170.165 1.00 29.42  ? 236  TRP C CE3   1 
ATOM   11407 C  CZ2   . TRP C 2 221  ? 123.845 133.944 167.394 1.00 29.42  ? 236  TRP C CZ2   1 
ATOM   11408 C  CZ3   . TRP C 2 221  ? 123.409 132.741 169.436 1.00 29.42  ? 236  TRP C CZ3   1 
ATOM   11409 C  CH2   . TRP C 2 221  ? 123.678 132.767 168.067 1.00 29.42  ? 236  TRP C CH2   1 
ATOM   11410 N  N     . TRP C 2 222  ? 121.412 134.835 172.743 1.00 29.95  ? 237  TRP C N     1 
ATOM   11411 C  CA    . TRP C 2 222  ? 120.914 133.464 172.768 1.00 29.95  ? 237  TRP C CA    1 
ATOM   11412 C  C     . TRP C 2 222  ? 119.417 133.412 173.047 1.00 29.95  ? 237  TRP C C     1 
ATOM   11413 O  O     . TRP C 2 222  ? 118.731 132.511 172.556 1.00 29.95  ? 237  TRP C O     1 
ATOM   11414 C  CB    . TRP C 2 222  ? 121.692 132.638 173.794 1.00 29.95  ? 237  TRP C CB    1 
ATOM   11415 C  CG    . TRP C 2 222  ? 123.044 132.210 173.295 1.00 29.95  ? 237  TRP C CG    1 
ATOM   11416 C  CD1   . TRP C 2 222  ? 124.228 132.869 173.459 1.00 29.95  ? 237  TRP C CD1   1 
ATOM   11417 C  CD2   . TRP C 2 222  ? 123.346 131.033 172.538 1.00 29.95  ? 237  TRP C CD2   1 
ATOM   11418 N  NE1   . TRP C 2 222  ? 125.246 132.175 172.855 1.00 29.95  ? 237  TRP C NE1   1 
ATOM   11419 C  CE2   . TRP C 2 222  ? 124.731 131.043 172.283 1.00 29.95  ? 237  TRP C CE2   1 
ATOM   11420 C  CE3   . TRP C 2 222  ? 122.579 129.972 172.054 1.00 29.95  ? 237  TRP C CE3   1 
ATOM   11421 C  CZ2   . TRP C 2 222  ? 125.363 130.033 171.566 1.00 29.95  ? 237  TRP C CZ2   1 
ATOM   11422 C  CZ3   . TRP C 2 222  ? 123.208 128.972 171.344 1.00 29.95  ? 237  TRP C CZ3   1 
ATOM   11423 C  CH2   . TRP C 2 222  ? 124.586 129.008 171.106 1.00 29.95  ? 237  TRP C CH2   1 
ATOM   11424 N  N     . ARG C 2 223  ? 118.893 134.361 173.825 1.00 34.38  ? 238  ARG C N     1 
ATOM   11425 C  CA    . ARG C 2 223  ? 117.460 134.422 174.082 1.00 34.38  ? 238  ARG C CA    1 
ATOM   11426 C  C     . ARG C 2 223  ? 116.667 134.976 172.907 1.00 34.38  ? 238  ARG C C     1 
ATOM   11427 O  O     . ARG C 2 223  ? 115.475 134.675 172.787 1.00 34.38  ? 238  ARG C O     1 
ATOM   11428 C  CB    . ARG C 2 223  ? 117.192 135.274 175.322 1.00 34.38  ? 238  ARG C CB    1 
ATOM   11429 C  CG    . ARG C 2 223  ? 117.547 134.596 176.627 1.00 34.38  ? 238  ARG C CG    1 
ATOM   11430 C  CD    . ARG C 2 223  ? 117.581 135.593 177.766 1.00 34.38  ? 238  ARG C CD    1 
ATOM   11431 N  NE    . ARG C 2 223  ? 117.564 134.935 179.065 1.00 34.38  ? 238  ARG C NE    1 
ATOM   11432 C  CZ    . ARG C 2 223  ? 117.742 135.560 180.220 1.00 34.38  ? 238  ARG C CZ    1 
ATOM   11433 N  NH1   . ARG C 2 223  ? 117.980 136.860 180.271 1.00 34.38  ? 238  ARG C NH1   1 
ATOM   11434 N  NH2   . ARG C 2 223  ? 117.683 134.863 181.351 1.00 34.38  ? 238  ARG C NH2   1 
ATOM   11435 N  N     . LYS C 2 224  ? 117.300 135.779 172.048 1.00 31.94  ? 239  LYS C N     1 
ATOM   11436 C  CA    . LYS C 2 224  ? 116.572 136.488 171.000 1.00 31.94  ? 239  LYS C CA    1 
ATOM   11437 C  C     . LYS C 2 224  ? 115.901 135.529 170.026 1.00 31.94  ? 239  LYS C C     1 
ATOM   11438 O  O     . LYS C 2 224  ? 114.740 135.727 169.651 1.00 31.94  ? 239  LYS C O     1 
ATOM   11439 C  CB    . LYS C 2 224  ? 117.523 137.427 170.260 1.00 31.94  ? 239  LYS C CB    1 
ATOM   11440 C  CG    . LYS C 2 224  ? 116.966 137.978 168.967 1.00 31.94  ? 239  LYS C CG    1 
ATOM   11441 C  CD    . LYS C 2 224  ? 117.806 139.135 168.460 1.00 31.94  ? 239  LYS C CD    1 
ATOM   11442 C  CE    . LYS C 2 224  ? 119.275 138.764 168.385 1.00 31.94  ? 239  LYS C CE    1 
ATOM   11443 N  NZ    . LYS C 2 224  ? 120.112 139.922 167.970 1.00 31.94  ? 239  LYS C NZ    1 
ATOM   11444 N  N     . PHE C 2 225  ? 116.609 134.485 169.610 1.00 33.87  ? 240  PHE C N     1 
ATOM   11445 C  CA    . PHE C 2 225  ? 116.069 133.533 168.651 1.00 33.87  ? 240  PHE C CA    1 
ATOM   11446 C  C     . PHE C 2 225  ? 115.207 132.460 169.299 1.00 33.87  ? 240  PHE C C     1 
ATOM   11447 O  O     . PHE C 2 225  ? 114.647 131.623 168.583 1.00 33.87  ? 240  PHE C O     1 
ATOM   11448 C  CB    . PHE C 2 225  ? 117.206 132.868 167.875 1.00 33.87  ? 240  PHE C CB    1 
ATOM   11449 C  CG    . PHE C 2 225  ? 118.144 133.838 167.225 1.00 33.87  ? 240  PHE C CG    1 
ATOM   11450 C  CD1   . PHE C 2 225  ? 117.869 134.354 165.974 1.00 33.87  ? 240  PHE C CD1   1 
ATOM   11451 C  CD2   . PHE C 2 225  ? 119.306 134.227 167.863 1.00 33.87  ? 240  PHE C CD2   1 
ATOM   11452 C  CE1   . PHE C 2 225  ? 118.732 135.244 165.374 1.00 33.87  ? 240  PHE C CE1   1 
ATOM   11453 C  CE2   . PHE C 2 225  ? 120.173 135.116 167.268 1.00 33.87  ? 240  PHE C CE2   1 
ATOM   11454 C  CZ    . PHE C 2 225  ? 119.886 135.625 166.022 1.00 33.87  ? 240  PHE C CZ    1 
ATOM   11455 N  N     . ALA C 2 226  ? 115.083 132.464 170.621 1.00 42.21  ? 241  ALA C N     1 
ATOM   11456 C  CA    . ALA C 2 226  ? 114.396 131.405 171.344 1.00 42.21  ? 241  ALA C CA    1 
ATOM   11457 C  C     . ALA C 2 226  ? 112.951 131.791 171.623 1.00 42.21  ? 241  ALA C C     1 
ATOM   11458 O  O     . ALA C 2 226  ? 112.662 132.928 172.005 1.00 42.21  ? 241  ALA C O     1 
ATOM   11459 C  CB    . ALA C 2 226  ? 115.112 131.094 172.658 1.00 42.21  ? 241  ALA C CB    1 
ATOM   11460 N  N     . MET C 2 227  ? 112.046 130.831 171.425 1.00 60.62  ? 242  MET C N     1 
ATOM   11461 C  CA    . MET C 2 227  ? 110.648 131.050 171.780 1.00 60.62  ? 242  MET C CA    1 
ATOM   11462 C  C     . MET C 2 227  ? 110.476 131.243 173.279 1.00 60.62  ? 242  MET C C     1 
ATOM   11463 O  O     . MET C 2 227  ? 109.580 131.976 173.712 1.00 60.62  ? 242  MET C O     1 
ATOM   11464 C  CB    . MET C 2 227  ? 109.795 129.874 171.307 1.00 60.62  ? 242  MET C CB    1 
ATOM   11465 C  CG    . MET C 2 227  ? 109.862 129.607 169.818 1.00 60.62  ? 242  MET C CG    1 
ATOM   11466 S  SD    . MET C 2 227  ? 109.010 128.082 169.377 1.00 60.62  ? 242  MET C SD    1 
ATOM   11467 C  CE    . MET C 2 227  ? 107.384 128.391 170.062 1.00 60.62  ? 242  MET C CE    1 
ATOM   11468 N  N     . SER C 2 228  ? 111.319 130.596 174.085 1.00 52.23  ? 243  SER C N     1 
ATOM   11469 C  CA    . SER C 2 228  ? 111.228 130.632 175.543 1.00 52.23  ? 243  SER C CA    1 
ATOM   11470 C  C     . SER C 2 228  ? 112.564 131.104 176.098 1.00 52.23  ? 243  SER C C     1 
ATOM   11471 O  O     . SER C 2 228  ? 113.444 130.285 176.406 1.00 52.23  ? 243  SER C O     1 
ATOM   11472 C  CB    . SER C 2 228  ? 110.852 129.262 176.104 1.00 52.23  ? 243  SER C CB    1 
ATOM   11473 O  OG    . SER C 2 228  ? 109.667 128.771 175.503 1.00 52.23  ? 243  SER C OG    1 
ATOM   11474 N  N     . PRO C 2 229  ? 112.765 132.417 176.242 1.00 45.58  ? 244  PRO C N     1 
ATOM   11475 C  CA    . PRO C 2 229  ? 114.039 132.921 176.774 1.00 45.58  ? 244  PRO C CA    1 
ATOM   11476 C  C     . PRO C 2 229  ? 114.248 132.637 178.252 1.00 45.58  ? 244  PRO C C     1 
ATOM   11477 O  O     . PRO C 2 229  ? 115.314 132.969 178.782 1.00 45.58  ? 244  PRO C O     1 
ATOM   11478 C  CB    . PRO C 2 229  ? 113.951 134.431 176.511 1.00 45.58  ? 244  PRO C CB    1 
ATOM   11479 C  CG    . PRO C 2 229  ? 112.495 134.720 176.471 1.00 45.58  ? 244  PRO C CG    1 
ATOM   11480 C  CD    . PRO C 2 229  ? 111.847 133.507 175.868 1.00 45.58  ? 244  PRO C CD    1 
ATOM   11481 N  N     . SER C 2 230  ? 113.268 132.038 178.934 1.00 48.80  ? 245  SER C N     1 
ATOM   11482 C  CA    . SER C 2 230  ? 113.440 131.671 180.334 1.00 48.80  ? 245  SER C CA    1 
ATOM   11483 C  C     . SER C 2 230  ? 114.299 130.424 180.496 1.00 48.80  ? 245  SER C C     1 
ATOM   11484 O  O     . SER C 2 230  ? 114.978 130.276 181.518 1.00 48.80  ? 245  SER C O     1 
ATOM   11485 C  CB    . SER C 2 230  ? 112.077 131.456 180.992 1.00 48.80  ? 245  SER C CB    1 
ATOM   11486 O  OG    . SER C 2 230  ? 111.365 130.409 180.355 1.00 48.80  ? 245  SER C OG    1 
ATOM   11487 N  N     . ASN C 2 231  ? 114.275 129.521 179.513 1.00 44.21  ? 246  ASN C N     1 
ATOM   11488 C  CA    . ASN C 2 231  ? 115.083 128.308 179.597 1.00 44.21  ? 246  ASN C CA    1 
ATOM   11489 C  C     . ASN C 2 231  ? 116.570 128.635 179.605 1.00 44.21  ? 246  ASN C C     1 
ATOM   11490 O  O     . ASN C 2 231  ? 117.347 128.005 180.332 1.00 44.21  ? 246  ASN C O     1 
ATOM   11491 C  CB    . ASN C 2 231  ? 114.741 127.370 178.442 1.00 44.21  ? 246  ASN C CB    1 
ATOM   11492 C  CG    . ASN C 2 231  ? 113.379 126.730 178.601 1.00 44.21  ? 246  ASN C CG    1 
ATOM   11493 O  OD1   . ASN C 2 231  ? 112.603 127.110 179.478 1.00 44.21  ? 246  ASN C OD1   1 
ATOM   11494 N  ND2   . ASN C 2 231  ? 113.078 125.755 177.753 1.00 44.21  ? 246  ASN C ND2   1 
ATOM   11495 N  N     . PHE C 2 232  ? 116.986 129.607 178.801 1.00 38.99  ? 247  PHE C N     1 
ATOM   11496 C  CA    . PHE C 2 232  ? 118.367 130.062 178.846 1.00 38.99  ? 247  PHE C CA    1 
ATOM   11497 C  C     . PHE C 2 232  ? 118.653 130.714 180.190 1.00 38.99  ? 247  PHE C C     1 
ATOM   11498 O  O     . PHE C 2 232  ? 117.817 131.437 180.738 1.00 38.99  ? 247  PHE C O     1 
ATOM   11499 C  CB    . PHE C 2 232  ? 118.643 131.042 177.709 1.00 38.99  ? 247  PHE C CB    1 
ATOM   11500 C  CG    . PHE C 2 232  ? 118.700 130.397 176.357 1.00 38.99  ? 247  PHE C CG    1 
ATOM   11501 C  CD1   . PHE C 2 232  ? 117.547 129.939 175.743 1.00 38.99  ? 247  PHE C CD1   1 
ATOM   11502 C  CD2   . PHE C 2 232  ? 119.906 130.251 175.698 1.00 38.99  ? 247  PHE C CD2   1 
ATOM   11503 C  CE1   . PHE C 2 232  ? 117.598 129.344 174.502 1.00 38.99  ? 247  PHE C CE1   1 
ATOM   11504 C  CE2   . PHE C 2 232  ? 119.961 129.658 174.456 1.00 38.99  ? 247  PHE C CE2   1 
ATOM   11505 C  CZ    . PHE C 2 232  ? 118.807 129.204 173.857 1.00 38.99  ? 247  PHE C CZ    1 
ATOM   11506 N  N     . SER C 2 233  ? 119.839 130.447 180.727 1.00 37.07  ? 248  SER C N     1 
ATOM   11507 C  CA    . SER C 2 233  ? 120.204 130.914 182.054 1.00 37.07  ? 248  SER C CA    1 
ATOM   11508 C  C     . SER C 2 233  ? 121.684 131.259 182.073 1.00 37.07  ? 248  SER C C     1 
ATOM   11509 O  O     . SER C 2 233  ? 122.426 130.971 181.131 1.00 37.07  ? 248  SER C O     1 
ATOM   11510 C  CB    . SER C 2 233  ? 119.878 129.865 183.121 1.00 37.07  ? 248  SER C CB    1 
ATOM   11511 O  OG    . SER C 2 233  ? 118.521 129.463 183.039 1.00 37.07  ? 248  SER C OG    1 
ATOM   11512 N  N     . SER C 2 234  ? 122.111 131.887 183.164 1.00 37.92  ? 249  SER C N     1 
ATOM   11513 C  CA    . SER C 2 234  ? 123.510 132.229 183.360 1.00 37.92  ? 249  SER C CA    1 
ATOM   11514 C  C     . SER C 2 234  ? 123.895 131.933 184.802 1.00 37.92  ? 249  SER C C     1 
ATOM   11515 O  O     . SER C 2 234  ? 123.044 131.851 185.691 1.00 37.92  ? 249  SER C O     1 
ATOM   11516 C  CB    . SER C 2 234  ? 123.790 133.698 183.019 1.00 37.92  ? 249  SER C CB    1 
ATOM   11517 O  OG    . SER C 2 234  ? 123.042 134.566 183.850 1.00 37.92  ? 249  SER C OG    1 
ATOM   11518 N  N     . ALA C 2 235  ? 125.196 131.766 185.023 1.00 46.84  ? 250  ALA C N     1 
ATOM   11519 C  CA    . ALA C 2 235  ? 125.719 131.468 186.349 1.00 46.84  ? 250  ALA C CA    1 
ATOM   11520 C  C     . ALA C 2 235  ? 127.197 131.826 186.377 1.00 46.84  ? 250  ALA C C     1 
ATOM   11521 O  O     . ALA C 2 235  ? 127.799 132.143 185.348 1.00 46.84  ? 250  ALA C O     1 
ATOM   11522 C  CB    . ALA C 2 235  ? 125.499 129.999 186.720 1.00 46.84  ? 250  ALA C CB    1 
ATOM   11523 N  N     . ASP C 2 236  ? 127.775 131.773 187.571 1.00 57.29  ? 251  ASP C N     1 
ATOM   11524 C  CA    . ASP C 2 236  ? 129.179 132.092 187.778 1.00 57.29  ? 251  ASP C CA    1 
ATOM   11525 C  C     . ASP C 2 236  ? 129.938 130.867 188.272 1.00 57.29  ? 251  ASP C C     1 
ATOM   11526 O  O     . ASP C 2 236  ? 129.354 129.871 188.709 1.00 57.29  ? 251  ASP C O     1 
ATOM   11527 C  CB    . ASP C 2 236  ? 129.336 133.249 188.771 1.00 57.29  ? 251  ASP C CB    1 
ATOM   11528 C  CG    . ASP C 2 236  ? 128.730 134.539 188.262 1.00 57.29  ? 251  ASP C CG    1 
ATOM   11529 O  OD1   . ASP C 2 236  ? 128.651 134.712 187.028 1.00 57.29  ? 251  ASP C OD1   1 
ATOM   11530 O  OD2   . ASP C 2 236  ? 128.333 135.380 189.095 1.00 57.29  ? 251  ASP C OD2   1 
ATOM   11531 N  N     . CYS C 2 237  ? 131.262 130.962 188.200 1.00 63.02  ? 252  CYS C N     1 
ATOM   11532 C  CA    . CYS C 2 237  ? 132.165 129.904 188.635 1.00 63.02  ? 252  CYS C CA    1 
ATOM   11533 C  C     . CYS C 2 237  ? 133.574 130.479 188.664 1.00 63.02  ? 252  CYS C C     1 
ATOM   11534 O  O     . CYS C 2 237  ? 133.812 131.607 188.225 1.00 63.02  ? 252  CYS C O     1 
ATOM   11535 C  CB    . CYS C 2 237  ? 132.083 128.680 187.720 1.00 63.02  ? 252  CYS C CB    1 
ATOM   11536 S  SG    . CYS C 2 237  ? 131.997 129.084 185.966 1.00 63.02  ? 252  CYS C SG    1 
ATOM   11537 N  N     . GLN C 2 238  ? 134.509 129.689 189.183 1.00 75.74  ? 253  GLN C N     1 
ATOM   11538 C  CA    . GLN C 2 238  ? 135.881 130.140 189.360 1.00 75.74  ? 253  GLN C CA    1 
ATOM   11539 C  C     . GLN C 2 238  ? 136.840 129.170 188.686 1.00 75.74  ? 253  GLN C C     1 
ATOM   11540 O  O     . GLN C 2 238  ? 136.609 127.958 188.657 1.00 75.74  ? 253  GLN C O     1 
ATOM   11541 C  CB    . GLN C 2 238  ? 136.229 130.285 190.845 1.00 75.74  ? 253  GLN C CB    1 
ATOM   11542 C  CG    . GLN C 2 238  ? 137.399 131.209 191.118 1.00 75.74  ? 253  GLN C CG    1 
ATOM   11543 C  CD    . GLN C 2 238  ? 137.437 131.681 192.556 1.00 75.74  ? 253  GLN C CD    1 
ATOM   11544 O  OE1   . GLN C 2 238  ? 136.605 131.285 193.372 1.00 75.74  ? 253  GLN C OE1   1 
ATOM   11545 N  NE2   . GLN C 2 238  ? 138.402 132.535 192.874 1.00 75.74  ? 253  GLN C NE2   1 
ATOM   11546 N  N     . ASP C 2 239  ? 137.922 129.722 188.144 1.00 74.88  ? 254  ASP C N     1 
ATOM   11547 C  CA    . ASP C 2 239  ? 138.899 128.943 187.402 1.00 74.88  ? 254  ASP C CA    1 
ATOM   11548 C  C     . ASP C 2 239  ? 139.822 128.195 188.365 1.00 74.88  ? 254  ASP C C     1 
ATOM   11549 O  O     . ASP C 2 239  ? 139.708 128.299 189.590 1.00 74.88  ? 254  ASP C O     1 
ATOM   11550 C  CB    . ASP C 2 239  ? 139.689 129.853 186.463 1.00 74.88  ? 254  ASP C CB    1 
ATOM   11551 C  CG    . ASP C 2 239  ? 140.334 129.098 185.317 1.00 74.88  ? 254  ASP C CG    1 
ATOM   11552 O  OD1   . ASP C 2 239  ? 140.178 127.860 185.256 1.00 74.88  ? 254  ASP C OD1   1 
ATOM   11553 O  OD2   . ASP C 2 239  ? 140.995 129.743 184.477 1.00 74.88  ? 254  ASP C OD2   1 
ATOM   11554 N  N     . GLU C 2 240  ? 140.747 127.420 187.795 1.00 76.87  ? 255  GLU C N     1 
ATOM   11555 C  CA    . GLU C 2 240  ? 141.717 126.693 188.608 1.00 76.87  ? 255  GLU C CA    1 
ATOM   11556 C  C     . GLU C 2 240  ? 142.615 127.649 189.381 1.00 76.87  ? 255  GLU C C     1 
ATOM   11557 O  O     . GLU C 2 240  ? 142.905 127.425 190.562 1.00 76.87  ? 255  GLU C O     1 
ATOM   11558 C  CB    . GLU C 2 240  ? 142.556 125.775 187.720 1.00 76.87  ? 255  GLU C CB    1 
ATOM   11559 C  CG    . GLU C 2 240  ? 141.741 124.901 186.784 1.00 76.87  ? 255  GLU C CG    1 
ATOM   11560 C  CD    . GLU C 2 240  ? 142.607 124.138 185.801 1.00 76.87  ? 255  GLU C CD    1 
ATOM   11561 O  OE1   . GLU C 2 240  ? 143.848 124.193 185.933 1.00 76.87  ? 255  GLU C OE1   1 
ATOM   11562 O  OE2   . GLU C 2 240  ? 142.047 123.487 184.894 1.00 76.87  ? 255  GLU C OE2   1 
ATOM   11563 N  N     . LEU C 2 241  ? 143.063 128.722 188.732 1.00 77.56  ? 256  LEU C N     1 
ATOM   11564 C  CA    . LEU C 2 241  ? 143.939 129.711 189.343 1.00 77.56  ? 256  LEU C CA    1 
ATOM   11565 C  C     . LEU C 2 241  ? 143.178 130.766 190.136 1.00 77.56  ? 256  LEU C C     1 
ATOM   11566 O  O     . LEU C 2 241  ? 143.739 131.830 190.425 1.00 77.56  ? 256  LEU C O     1 
ATOM   11567 C  CB    . LEU C 2 241  ? 144.800 130.391 188.274 1.00 77.56  ? 256  LEU C CB    1 
ATOM   11568 C  CG    . LEU C 2 241  ? 145.922 129.595 187.597 1.00 77.56  ? 256  LEU C CG    1 
ATOM   11569 C  CD1   . LEU C 2 241  ? 145.386 128.607 186.568 1.00 77.56  ? 256  LEU C CD1   1 
ATOM   11570 C  CD2   . LEU C 2 241  ? 146.928 130.540 186.957 1.00 77.56  ? 256  LEU C CD2   1 
ATOM   11571 N  N     . GLY C 2 242  ? 141.923 130.503 190.492 1.00 72.68  ? 257  GLY C N     1 
ATOM   11572 C  CA    . GLY C 2 242  ? 141.114 131.471 191.198 1.00 72.68  ? 257  GLY C CA    1 
ATOM   11573 C  C     . GLY C 2 242  ? 140.508 132.552 190.334 1.00 72.68  ? 257  GLY C C     1 
ATOM   11574 O  O     . GLY C 2 242  ? 139.861 133.461 190.871 1.00 72.68  ? 257  GLY C O     1 
ATOM   11575 N  N     . ARG C 2 243  ? 140.696 132.491 189.019 1.00 69.71  ? 258  ARG C N     1 
ATOM   11576 C  CA    . ARG C 2 243  ? 140.125 133.493 188.132 1.00 69.71  ? 258  ARG C CA    1 
ATOM   11577 C  C     . ARG C 2 243  ? 138.613 133.329 188.043 1.00 69.71  ? 258  ARG C C     1 
ATOM   11578 O  O     . ARG C 2 243  ? 138.095 132.211 187.979 1.00 69.71  ? 258  ARG C O     1 
ATOM   11579 C  CB    . ARG C 2 243  ? 140.760 133.389 186.747 1.00 69.71  ? 258  ARG C CB    1 
ATOM   11580 C  CG    . ARG C 2 243  ? 142.277 133.467 186.779 1.00 69.71  ? 258  ARG C CG    1 
ATOM   11581 C  CD    . ARG C 2 243  ? 142.885 133.370 185.392 1.00 69.71  ? 258  ARG C CD    1 
ATOM   11582 N  NE    . ARG C 2 243  ? 142.637 132.079 184.763 1.00 69.71  ? 258  ARG C NE    1 
ATOM   11583 C  CZ    . ARG C 2 243  ? 143.237 131.659 183.658 1.00 69.71  ? 258  ARG C CZ    1 
ATOM   11584 N  NH1   . ARG C 2 243  ? 144.139 132.402 183.037 1.00 69.71  ? 258  ARG C NH1   1 
ATOM   11585 N  NH2   . ARG C 2 243  ? 142.927 130.463 183.166 1.00 69.71  ? 258  ARG C NH2   1 
ATOM   11586 N  N     . LYS C 2 244  ? 137.906 134.455 188.042 1.00 66.78  ? 259  LYS C N     1 
ATOM   11587 C  CA    . LYS C 2 244  ? 136.450 134.457 188.024 1.00 66.78  ? 259  LYS C CA    1 
ATOM   11588 C  C     . LYS C 2 244  ? 135.939 134.418 186.590 1.00 66.78  ? 259  LYS C C     1 
ATOM   11589 O  O     . LYS C 2 244  ? 136.527 135.023 185.690 1.00 66.78  ? 259  LYS C O     1 
ATOM   11590 C  CB    . LYS C 2 244  ? 135.909 135.694 188.744 1.00 66.78  ? 259  LYS C CB    1 
ATOM   11591 C  CG    . LYS C 2 244  ? 134.391 135.789 188.786 1.00 66.78  ? 259  LYS C CG    1 
ATOM   11592 C  CD    . LYS C 2 244  ? 133.777 134.602 189.510 1.00 66.78  ? 259  LYS C CD    1 
ATOM   11593 C  CE    . LYS C 2 244  ? 134.210 134.559 190.966 1.00 66.78  ? 259  LYS C CE    1 
ATOM   11594 N  NZ    . LYS C 2 244  ? 133.606 133.408 191.691 1.00 66.78  ? 259  LYS C NZ    1 
ATOM   11595 N  N     . GLY C 2 245  ? 134.839 133.699 186.384 1.00 53.69  ? 260  GLY C N     1 
ATOM   11596 C  CA    . GLY C 2 245  ? 134.252 133.591 185.062 1.00 53.69  ? 260  GLY C CA    1 
ATOM   11597 C  C     . GLY C 2 245  ? 132.778 133.262 185.144 1.00 53.69  ? 260  GLY C C     1 
ATOM   11598 O  O     . GLY C 2 245  ? 132.280 132.781 186.166 1.00 53.69  ? 260  GLY C O     1 
ATOM   11599 N  N     . SER C 2 246  ? 132.083 133.528 184.043 1.00 46.56  ? 261  SER C N     1 
ATOM   11600 C  CA    . SER C 2 246  ? 130.646 133.323 183.945 1.00 46.56  ? 261  SER C CA    1 
ATOM   11601 C  C     . SER C 2 246  ? 130.351 132.255 182.905 1.00 46.56  ? 261  SER C C     1 
ATOM   11602 O  O     . SER C 2 246  ? 131.010 132.190 181.863 1.00 46.56  ? 261  SER C O     1 
ATOM   11603 C  CB    . SER C 2 246  ? 129.926 134.623 183.575 1.00 46.56  ? 261  SER C CB    1 
ATOM   11604 O  OG    . SER C 2 246  ? 130.231 135.657 184.495 1.00 46.56  ? 261  SER C OG    1 
ATOM   11605 N  N     . LYS C 2 247  ? 129.355 131.420 183.188 1.00 38.65  ? 262  LYS C N     1 
ATOM   11606 C  CA    . LYS C 2 247  ? 128.948 130.349 182.292 1.00 38.65  ? 262  LYS C CA    1 
ATOM   11607 C  C     . LYS C 2 247  ? 127.488 130.526 181.912 1.00 38.65  ? 262  LYS C C     1 
ATOM   11608 O  O     . LYS C 2 247  ? 126.623 130.624 182.788 1.00 38.65  ? 262  LYS C O     1 
ATOM   11609 C  CB    . LYS C 2 247  ? 129.151 128.976 182.935 1.00 38.65  ? 262  LYS C CB    1 
ATOM   11610 C  CG    . LYS C 2 247  ? 130.553 128.424 182.805 1.00 38.65  ? 262  LYS C CG    1 
ATOM   11611 C  CD    . LYS C 2 247  ? 130.599 126.962 183.211 1.00 38.65  ? 262  LYS C CD    1 
ATOM   11612 C  CE    . LYS C 2 247  ? 131.971 126.360 182.958 1.00 38.65  ? 262  LYS C CE    1 
ATOM   11613 N  NZ    . LYS C 2 247  ? 132.007 124.907 183.284 1.00 38.65  ? 262  LYS C NZ    1 
ATOM   11614 N  N     . LEU C 2 248  ? 127.220 130.566 180.613 1.00 33.32  ? 263  LEU C N     1 
ATOM   11615 C  CA    . LEU C 2 248  ? 125.856 130.552 180.111 1.00 33.32  ? 263  LEU C CA    1 
ATOM   11616 C  C     . LEU C 2 248  ? 125.341 129.122 180.071 1.00 33.32  ? 263  LEU C C     1 
ATOM   11617 O  O     . LEU C 2 248  ? 126.108 128.168 179.930 1.00 33.32  ? 263  LEU C O     1 
ATOM   11618 C  CB    . LEU C 2 248  ? 125.777 131.178 178.720 1.00 33.32  ? 263  LEU C CB    1 
ATOM   11619 C  CG    . LEU C 2 248  ? 125.977 132.689 178.649 1.00 33.32  ? 263  LEU C CG    1 
ATOM   11620 C  CD1   . LEU C 2 248  ? 125.933 133.159 177.211 1.00 33.32  ? 263  LEU C CD1   1 
ATOM   11621 C  CD2   . LEU C 2 248  ? 124.914 133.387 179.470 1.00 33.32  ? 263  LEU C CD2   1 
ATOM   11622 N  N     . TYR C 2 249  ? 124.028 128.980 180.199 1.00 35.99  ? 264  TYR C N     1 
ATOM   11623 C  CA    . TYR C 2 249  ? 123.410 127.668 180.271 1.00 35.99  ? 264  TYR C CA    1 
ATOM   11624 C  C     . TYR C 2 249  ? 122.139 127.652 179.442 1.00 35.99  ? 264  TYR C C     1 
ATOM   11625 O  O     . TYR C 2 249  ? 121.513 128.688 179.212 1.00 35.99  ? 264  TYR C O     1 
ATOM   11626 C  CB    . TYR C 2 249  ? 123.070 127.278 181.716 1.00 35.99  ? 264  TYR C CB    1 
ATOM   11627 C  CG    . TYR C 2 249  ? 124.251 126.853 182.557 1.00 35.99  ? 264  TYR C CG    1 
ATOM   11628 C  CD1   . TYR C 2 249  ? 125.100 127.792 183.122 1.00 35.99  ? 264  TYR C CD1   1 
ATOM   11629 C  CD2   . TYR C 2 249  ? 124.505 125.511 182.801 1.00 35.99  ? 264  TYR C CD2   1 
ATOM   11630 C  CE1   . TYR C 2 249  ? 126.174 127.407 183.895 1.00 35.99  ? 264  TYR C CE1   1 
ATOM   11631 C  CE2   . TYR C 2 249  ? 125.576 125.116 183.574 1.00 35.99  ? 264  TYR C CE2   1 
ATOM   11632 C  CZ    . TYR C 2 249  ? 126.409 126.069 184.118 1.00 35.99  ? 264  TYR C CZ    1 
ATOM   11633 O  OH    . TYR C 2 249  ? 127.480 125.683 184.890 1.00 35.99  ? 264  TYR C OH    1 
ATOM   11634 N  N     . TYR C 2 250  ? 121.770 126.460 178.990 1.00 42.44  ? 265  TYR C N     1 
ATOM   11635 C  CA    . TYR C 2 250  ? 120.440 126.189 178.473 1.00 42.44  ? 265  TYR C CA    1 
ATOM   11636 C  C     . TYR C 2 250  ? 119.859 125.022 179.254 1.00 42.44  ? 265  TYR C C     1 
ATOM   11637 O  O     . TYR C 2 250  ? 120.548 124.030 179.505 1.00 42.44  ? 265  TYR C O     1 
ATOM   11638 C  CB    . TYR C 2 250  ? 120.456 125.868 176.976 1.00 42.44  ? 265  TYR C CB    1 
ATOM   11639 C  CG    . TYR C 2 250  ? 119.112 125.413 176.453 1.00 42.44  ? 265  TYR C CG    1 
ATOM   11640 C  CD1   . TYR C 2 250  ? 118.148 126.330 176.068 1.00 42.44  ? 265  TYR C CD1   1 
ATOM   11641 C  CD2   . TYR C 2 250  ? 118.804 124.064 176.355 1.00 42.44  ? 265  TYR C CD2   1 
ATOM   11642 C  CE1   . TYR C 2 250  ? 116.917 125.917 175.597 1.00 42.44  ? 265  TYR C CE1   1 
ATOM   11643 C  CE2   . TYR C 2 250  ? 117.577 123.643 175.888 1.00 42.44  ? 265  TYR C CE2   1 
ATOM   11644 C  CZ    . TYR C 2 250  ? 116.638 124.573 175.510 1.00 42.44  ? 265  TYR C CZ    1 
ATOM   11645 O  OH    . TYR C 2 250  ? 115.415 124.153 175.043 1.00 42.44  ? 265  TYR C OH    1 
ATOM   11646 N  N     . SER C 2 251  ? 118.593 125.143 179.639 1.00 43.85  ? 266  SER C N     1 
ATOM   11647 C  CA    . SER C 2 251  ? 117.936 124.107 180.433 1.00 43.85  ? 266  SER C CA    1 
ATOM   11648 C  C     . SER C 2 251  ? 117.399 123.040 179.489 1.00 43.85  ? 266  SER C C     1 
ATOM   11649 O  O     . SER C 2 251  ? 116.234 123.059 179.088 1.00 43.85  ? 266  SER C O     1 
ATOM   11650 C  CB    . SER C 2 251  ? 116.828 124.703 181.289 1.00 43.85  ? 266  SER C CB    1 
ATOM   11651 O  OG    . SER C 2 251  ? 115.754 125.153 180.485 1.00 43.85  ? 266  SER C OG    1 
ATOM   11652 N  N     . PHE C 2 252  ? 118.263 122.094 179.129 1.00 46.18  ? 267  PHE C N     1 
ATOM   11653 C  CA    . PHE C 2 252  ? 117.844 120.962 178.324 1.00 46.18  ? 267  PHE C CA    1 
ATOM   11654 C  C     . PHE C 2 252  ? 116.883 120.086 179.123 1.00 46.18  ? 267  PHE C C     1 
ATOM   11655 O  O     . PHE C 2 252  ? 116.860 120.140 180.355 1.00 46.18  ? 267  PHE C O     1 
ATOM   11656 C  CB    . PHE C 2 252  ? 119.054 120.146 177.878 1.00 46.18  ? 267  PHE C CB    1 
ATOM   11657 C  CG    . PHE C 2 252  ? 119.830 120.769 176.756 1.00 46.18  ? 267  PHE C CG    1 
ATOM   11658 C  CD1   . PHE C 2 252  ? 119.432 120.593 175.444 1.00 46.18  ? 267  PHE C CD1   1 
ATOM   11659 C  CD2   . PHE C 2 252  ? 120.963 121.519 177.012 1.00 46.18  ? 267  PHE C CD2   1 
ATOM   11660 C  CE1   . PHE C 2 252  ? 120.145 121.158 174.409 1.00 46.18  ? 267  PHE C CE1   1 
ATOM   11661 C  CE2   . PHE C 2 252  ? 121.681 122.088 175.980 1.00 46.18  ? 267  PHE C CE2   1 
ATOM   11662 C  CZ    . PHE C 2 252  ? 121.270 121.907 174.678 1.00 46.18  ? 267  PHE C CZ    1 
ATOM   11663 N  N     . PRO C 2 253  ? 116.068 119.274 178.443 1.00 53.79  ? 268  PRO C N     1 
ATOM   11664 C  CA    . PRO C 2 253  ? 115.124 118.414 179.176 1.00 53.79  ? 268  PRO C CA    1 
ATOM   11665 C  C     . PRO C 2 253  ? 115.794 117.462 180.153 1.00 53.79  ? 268  PRO C C     1 
ATOM   11666 O  O     . PRO C 2 253  ? 115.165 117.069 181.144 1.00 53.79  ? 268  PRO C O     1 
ATOM   11667 C  CB    . PRO C 2 253  ? 114.397 117.655 178.054 1.00 53.79  ? 268  PRO C CB    1 
ATOM   11668 C  CG    . PRO C 2 253  ? 115.278 117.792 176.853 1.00 53.79  ? 268  PRO C CG    1 
ATOM   11669 C  CD    . PRO C 2 253  ? 115.912 119.137 176.986 1.00 53.79  ? 268  PRO C CD    1 
ATOM   11670 N  N     . TRP C 2 254  ? 117.044 117.077 179.912 1.00 52.26  ? 269  TRP C N     1 
ATOM   11671 C  CA    . TRP C 2 254  ? 117.781 116.241 180.850 1.00 52.26  ? 269  TRP C CA    1 
ATOM   11672 C  C     . TRP C 2 254  ? 118.568 117.048 181.874 1.00 52.26  ? 269  TRP C C     1 
ATOM   11673 O  O     . TRP C 2 254  ? 119.192 116.455 182.760 1.00 52.26  ? 269  TRP C O     1 
ATOM   11674 C  CB    . TRP C 2 254  ? 118.732 115.304 180.097 1.00 52.26  ? 269  TRP C CB    1 
ATOM   11675 C  CG    . TRP C 2 254  ? 119.757 116.013 179.270 1.00 52.26  ? 269  TRP C CG    1 
ATOM   11676 C  CD1   . TRP C 2 254  ? 120.897 116.618 179.714 1.00 52.26  ? 269  TRP C CD1   1 
ATOM   11677 C  CD2   . TRP C 2 254  ? 119.742 116.182 177.849 1.00 52.26  ? 269  TRP C CD2   1 
ATOM   11678 N  NE1   . TRP C 2 254  ? 121.588 117.159 178.658 1.00 52.26  ? 269  TRP C NE1   1 
ATOM   11679 C  CE2   . TRP C 2 254  ? 120.900 116.904 177.501 1.00 52.26  ? 269  TRP C CE2   1 
ATOM   11680 C  CE3   . TRP C 2 254  ? 118.860 115.795 176.837 1.00 52.26  ? 269  TRP C CE3   1 
ATOM   11681 C  CZ2   . TRP C 2 254  ? 121.199 117.246 176.186 1.00 52.26  ? 269  TRP C CZ2   1 
ATOM   11682 C  CZ3   . TRP C 2 254  ? 119.158 116.136 175.532 1.00 52.26  ? 269  TRP C CZ3   1 
ATOM   11683 C  CH2   . TRP C 2 254  ? 120.317 116.854 175.218 1.00 52.26  ? 269  TRP C CH2   1 
ATOM   11684 N  N     . GLY C 2 255  ? 118.559 118.372 181.781 1.00 48.73  ? 270  GLY C N     1 
ATOM   11685 C  CA    . GLY C 2 255  ? 119.278 119.223 182.707 1.00 48.73  ? 270  GLY C CA    1 
ATOM   11686 C  C     . GLY C 2 255  ? 120.132 120.246 181.985 1.00 48.73  ? 270  GLY C C     1 
ATOM   11687 O  O     . GLY C 2 255  ? 120.287 120.230 180.766 1.00 48.73  ? 270  GLY C O     1 
ATOM   11688 N  N     . LYS C 2 256  ? 120.694 121.150 182.784 1.00 40.94  ? 271  LYS C N     1 
ATOM   11689 C  CA    . LYS C 2 256  ? 121.500 122.233 182.238 1.00 40.94  ? 271  LYS C CA    1 
ATOM   11690 C  C     . LYS C 2 256  ? 122.768 121.704 181.581 1.00 40.94  ? 271  LYS C C     1 
ATOM   11691 O  O     . LYS C 2 256  ? 123.463 120.845 182.130 1.00 40.94  ? 271  LYS C O     1 
ATOM   11692 C  CB    . LYS C 2 256  ? 121.870 123.228 183.335 1.00 40.94  ? 271  LYS C CB    1 
ATOM   11693 C  CG    . LYS C 2 256  ? 120.854 124.330 183.565 1.00 40.94  ? 271  LYS C CG    1 
ATOM   11694 C  CD    . LYS C 2 256  ? 121.429 125.395 184.484 1.00 40.94  ? 271  LYS C CD    1 
ATOM   11695 C  CE    . LYS C 2 256  ? 120.519 126.604 184.579 1.00 40.94  ? 271  LYS C CE    1 
ATOM   11696 N  NZ    . LYS C 2 256  ? 121.112 127.663 185.442 1.00 40.94  ? 271  LYS C NZ    1 
ATOM   11697 N  N     . GLU C 2 257  ? 123.066 122.230 180.395 1.00 41.78  ? 272  GLU C N     1 
ATOM   11698 C  CA    . GLU C 2 257  ? 124.315 121.956 179.693 1.00 41.78  ? 272  GLU C CA    1 
ATOM   11699 C  C     . GLU C 2 257  ? 124.881 123.293 179.240 1.00 41.78  ? 272  GLU C C     1 
ATOM   11700 O  O     . GLU C 2 257  ? 124.215 124.013 178.468 1.00 41.78  ? 272  GLU C O     1 
ATOM   11701 C  CB    . GLU C 2 257  ? 124.104 121.017 178.503 1.00 41.78  ? 272  GLU C CB    1 
ATOM   11702 C  CG    . GLU C 2 257  ? 124.090 119.540 178.861 1.00 41.78  ? 272  GLU C CG    1 
ATOM   11703 C  CD    . GLU C 2 257  ? 125.473 119.000 179.176 1.00 41.78  ? 272  GLU C CD    1 
ATOM   11704 O  OE1   . GLU C 2 257  ? 126.469 119.699 178.893 1.00 41.78  ? 272  GLU C OE1   1 
ATOM   11705 O  OE2   . GLU C 2 257  ? 125.563 117.873 179.706 1.00 41.78  ? 272  GLU C OE2   1 
ATOM   11706 N  N     . PRO C 2 258  ? 126.079 123.672 179.675 1.00 33.56  ? 273  PRO C N     1 
ATOM   11707 C  CA    . PRO C 2 258  ? 126.588 125.009 179.344 1.00 33.56  ? 273  PRO C CA    1 
ATOM   11708 C  C     . PRO C 2 258  ? 126.904 125.163 177.866 1.00 33.56  ? 273  PRO C C     1 
ATOM   11709 O  O     . PRO C 2 258  ? 127.869 124.582 177.362 1.00 33.56  ? 273  PRO C O     1 
ATOM   11710 C  CB    . PRO C 2 258  ? 127.852 125.124 180.205 1.00 33.56  ? 273  PRO C CB    1 
ATOM   11711 C  CG    . PRO C 2 258  ? 128.281 123.721 180.425 1.00 33.56  ? 273  PRO C CG    1 
ATOM   11712 C  CD    . PRO C 2 258  ? 127.022 122.910 180.509 1.00 33.56  ? 273  PRO C CD    1 
ATOM   11713 N  N     . ILE C 2 259  ? 126.087 125.952 177.164 1.00 32.72  ? 274  ILE C N     1 
ATOM   11714 C  CA    . ILE C 2 259  ? 126.301 126.197 175.739 1.00 32.72  ? 274  ILE C CA    1 
ATOM   11715 C  C     . ILE C 2 259  ? 127.295 127.312 175.475 1.00 32.72  ? 274  ILE C C     1 
ATOM   11716 O  O     . ILE C 2 259  ? 127.679 127.523 174.319 1.00 32.72  ? 274  ILE C O     1 
ATOM   11717 C  CB    . ILE C 2 259  ? 124.976 126.544 175.038 1.00 32.72  ? 274  ILE C CB    1 
ATOM   11718 C  CG1   . ILE C 2 259  ? 124.426 127.853 175.595 1.00 32.72  ? 274  ILE C CG1   1 
ATOM   11719 C  CG2   . ILE C 2 259  ? 123.967 125.428 175.223 1.00 32.72  ? 274  ILE C CG2   1 
ATOM   11720 C  CD1   . ILE C 2 259  ? 123.049 128.188 175.100 1.00 32.72  ? 274  ILE C CD1   1 
ATOM   11721 N  N     . GLU C 2 260  ? 127.718 128.036 176.505 1.00 30.89  ? 275  GLU C N     1 
ATOM   11722 C  CA    . GLU C 2 260  ? 128.698 129.098 176.339 1.00 30.89  ? 275  GLU C CA    1 
ATOM   11723 C  C     . GLU C 2 260  ? 129.381 129.323 177.677 1.00 30.89  ? 275  GLU C C     1 
ATOM   11724 O  O     . GLU C 2 260  ? 128.843 128.982 178.731 1.00 30.89  ? 275  GLU C O     1 
ATOM   11725 C  CB    . GLU C 2 260  ? 128.045 130.382 175.820 1.00 30.89  ? 275  GLU C CB    1 
ATOM   11726 C  CG    . GLU C 2 260  ? 129.020 131.424 175.308 1.00 30.89  ? 275  GLU C CG    1 
ATOM   11727 C  CD    . GLU C 2 260  ? 128.366 132.409 174.365 1.00 30.89  ? 275  GLU C CD    1 
ATOM   11728 O  OE1   . GLU C 2 260  ? 127.253 132.119 173.881 1.00 30.89  ? 275  GLU C OE1   1 
ATOM   11729 O  OE2   . GLU C 2 260  ? 128.965 133.472 174.106 1.00 30.89  ? 275  GLU C OE2   1 
ATOM   11730 N  N     . THR C 2 261  ? 130.576 129.904 177.622 1.00 36.52  ? 276  THR C N     1 
ATOM   11731 C  CA    . THR C 2 261  ? 131.393 130.058 178.818 1.00 36.52  ? 276  THR C CA    1 
ATOM   11732 C  C     . THR C 2 261  ? 132.317 131.254 178.649 1.00 36.52  ? 276  THR C C     1 
ATOM   11733 O  O     . THR C 2 261  ? 132.962 131.399 177.607 1.00 36.52  ? 276  THR C O     1 
ATOM   11734 C  CB    . THR C 2 261  ? 132.206 128.788 179.088 1.00 36.52  ? 276  THR C CB    1 
ATOM   11735 O  OG1   . THR C 2 261  ? 131.316 127.685 179.299 1.00 36.52  ? 276  THR C OG1   1 
ATOM   11736 C  CG2   . THR C 2 261  ? 133.075 128.963 180.313 1.00 36.52  ? 276  THR C CG2   1 
ATOM   11737 N  N     . LEU C 2 262  ? 132.374 132.103 179.670 1.00 40.71  ? 277  LEU C N     1 
ATOM   11738 C  CA    . LEU C 2 262  ? 133.222 133.286 179.671 1.00 40.71  ? 277  LEU C CA    1 
ATOM   11739 C  C     . LEU C 2 262  ? 134.185 133.210 180.846 1.00 40.71  ? 277  LEU C C     1 
ATOM   11740 O  O     . LEU C 2 262  ? 133.755 133.042 181.991 1.00 40.71  ? 277  LEU C O     1 
ATOM   11741 C  CB    . LEU C 2 262  ? 132.387 134.568 179.756 1.00 40.71  ? 277  LEU C CB    1 
ATOM   11742 C  CG    . LEU C 2 262  ? 131.346 134.845 178.665 1.00 40.71  ? 277  LEU C CG    1 
ATOM   11743 C  CD1   . LEU C 2 262  ? 129.999 134.202 178.982 1.00 40.71  ? 277  LEU C CD1   1 
ATOM   11744 C  CD2   . LEU C 2 262  ? 131.190 136.340 178.448 1.00 40.71  ? 277  LEU C CD2   1 
ATOM   11745 N  N     . TRP C 2 263  ? 135.479 133.334 180.562 1.00 48.64  ? 278  TRP C N     1 
ATOM   11746 C  CA    . TRP C 2 263  ? 136.516 133.334 181.583 1.00 48.64  ? 278  TRP C CA    1 
ATOM   11747 C  C     . TRP C 2 263  ? 137.284 134.644 181.535 1.00 48.64  ? 278  TRP C C     1 
ATOM   11748 O  O     . TRP C 2 263  ? 137.470 135.230 180.468 1.00 48.64  ? 278  TRP C O     1 
ATOM   11749 C  CB    . TRP C 2 263  ? 137.510 132.182 181.398 1.00 48.64  ? 278  TRP C CB    1 
ATOM   11750 C  CG    . TRP C 2 263  ? 136.913 130.827 181.492 1.00 48.64  ? 278  TRP C CG    1 
ATOM   11751 C  CD1   . TRP C 2 263  ? 136.845 129.897 180.502 1.00 48.64  ? 278  TRP C CD1   1 
ATOM   11752 C  CD2   . TRP C 2 263  ? 136.299 130.238 182.642 1.00 48.64  ? 278  TRP C CD2   1 
ATOM   11753 N  NE1   . TRP C 2 263  ? 136.228 128.761 180.962 1.00 48.64  ? 278  TRP C NE1   1 
ATOM   11754 C  CE2   . TRP C 2 263  ? 135.880 128.946 182.274 1.00 48.64  ? 278  TRP C CE2   1 
ATOM   11755 C  CE3   . TRP C 2 263  ? 136.062 130.677 183.947 1.00 48.64  ? 278  TRP C CE3   1 
ATOM   11756 C  CZ2   . TRP C 2 263  ? 135.236 128.089 183.161 1.00 48.64  ? 278  TRP C CZ2   1 
ATOM   11757 C  CZ3   . TRP C 2 263  ? 135.422 129.826 184.827 1.00 48.64  ? 278  TRP C CZ3   1 
ATOM   11758 C  CH2   . TRP C 2 263  ? 135.017 128.546 184.430 1.00 48.64  ? 278  TRP C CH2   1 
ATOM   11759 N  N     . ASN C 2 264  ? 137.739 135.096 182.703 1.00 55.16  ? 279  ASN C N     1 
ATOM   11760 C  CA    . ASN C 2 264  ? 138.605 136.270 182.788 1.00 55.16  ? 279  ASN C CA    1 
ATOM   11761 C  C     . ASN C 2 264  ? 140.033 135.772 182.992 1.00 55.16  ? 279  ASN C C     1 
ATOM   11762 O  O     . ASN C 2 264  ? 140.553 135.707 184.106 1.00 55.16  ? 279  ASN C O     1 
ATOM   11763 C  CB    . ASN C 2 264  ? 138.153 137.204 183.904 1.00 55.16  ? 279  ASN C CB    1 
ATOM   11764 C  CG    . ASN C 2 264  ? 138.731 138.596 183.762 1.00 55.16  ? 279  ASN C CG    1 
ATOM   11765 O  OD1   . ASN C 2 264  ? 139.045 139.040 182.658 1.00 55.16  ? 279  ASN C OD1   1 
ATOM   11766 N  ND2   . ASN C 2 264  ? 138.877 139.294 184.882 1.00 55.16  ? 279  ASN C ND2   1 
ATOM   11767 N  N     . LEU C 2 265  ? 140.671 135.416 181.876 1.00 58.92  ? 280  LEU C N     1 
ATOM   11768 C  CA    . LEU C 2 265  ? 141.982 134.779 181.933 1.00 58.92  ? 280  LEU C CA    1 
ATOM   11769 C  C     . LEU C 2 265  ? 143.063 135.751 182.390 1.00 58.92  ? 280  LEU C C     1 
ATOM   11770 O  O     . LEU C 2 265  ? 143.935 135.386 183.186 1.00 58.92  ? 280  LEU C O     1 
ATOM   11771 C  CB    . LEU C 2 265  ? 142.329 134.194 180.567 1.00 58.92  ? 280  LEU C CB    1 
ATOM   11772 C  CG    . LEU C 2 265  ? 141.264 133.296 179.937 1.00 58.92  ? 280  LEU C CG    1 
ATOM   11773 C  CD1   . LEU C 2 265  ? 141.609 133.005 178.492 1.00 58.92  ? 280  LEU C CD1   1 
ATOM   11774 C  CD2   . LEU C 2 265  ? 141.117 132.005 180.723 1.00 58.92  ? 280  LEU C CD2   1 
ATOM   11775 N  N     . GLY C 2 266  ? 143.031 136.980 181.898 1.00 66.32  ? 281  GLY C N     1 
ATOM   11776 C  CA    . GLY C 2 266  ? 144.039 137.953 182.264 1.00 66.32  ? 281  GLY C CA    1 
ATOM   11777 C  C     . GLY C 2 266  ? 145.209 137.985 181.303 1.00 66.32  ? 281  GLY C C     1 
ATOM   11778 O  O     . GLY C 2 266  ? 145.235 137.324 180.261 1.00 66.32  ? 281  GLY C O     1 
ATOM   11779 N  N     . ASP C 2 267  ? 146.207 138.788 181.677 1.00 71.80  ? 282  ASP C N     1 
ATOM   11780 C  CA    . ASP C 2 267  ? 147.410 138.946 180.867 1.00 71.80  ? 282  ASP C CA    1 
ATOM   11781 C  C     . ASP C 2 267  ? 148.288 137.701 180.855 1.00 71.80  ? 282  ASP C C     1 
ATOM   11782 O  O     . ASP C 2 267  ? 149.234 137.642 180.061 1.00 71.80  ? 282  ASP C O     1 
ATOM   11783 C  CB    . ASP C 2 267  ? 148.225 140.141 181.367 1.00 71.80  ? 282  ASP C CB    1 
ATOM   11784 C  CG    . ASP C 2 267  ? 148.650 139.991 182.816 1.00 71.80  ? 282  ASP C CG    1 
ATOM   11785 O  OD1   . ASP C 2 267  ? 147.854 139.458 183.618 1.00 71.80  ? 282  ASP C OD1   1 
ATOM   11786 O  OD2   . ASP C 2 267  ? 149.779 140.406 183.153 1.00 71.80  ? 282  ASP C OD2   1 
ATOM   11787 N  N     . GLN C 2 268  ? 148.008 136.719 181.714 1.00 70.47  ? 283  GLN C N     1 
ATOM   11788 C  CA    . GLN C 2 268  ? 148.851 135.529 181.786 1.00 70.47  ? 283  GLN C CA    1 
ATOM   11789 C  C     . GLN C 2 268  ? 148.820 134.738 180.484 1.00 70.47  ? 283  GLN C C     1 
ATOM   11790 O  O     . GLN C 2 268  ? 149.852 134.218 180.042 1.00 70.47  ? 283  GLN C O     1 
ATOM   11791 C  CB    . GLN C 2 268  ? 148.413 134.653 182.959 1.00 70.47  ? 283  GLN C CB    1 
ATOM   11792 C  CG    . GLN C 2 268  ? 149.209 133.368 183.103 1.00 70.47  ? 283  GLN C CG    1 
ATOM   11793 C  CD    . GLN C 2 268  ? 148.829 132.581 184.340 1.00 70.47  ? 283  GLN C CD    1 
ATOM   11794 O  OE1   . GLN C 2 268  ? 148.285 133.131 185.298 1.00 70.47  ? 283  GLN C OE1   1 
ATOM   11795 N  NE2   . GLN C 2 268  ? 149.112 131.284 184.326 1.00 70.47  ? 283  GLN C NE2   1 
ATOM   11796 N  N     . GLU C 2 269  ? 147.646 134.626 179.858 1.00 67.37  ? 284  GLU C N     1 
ATOM   11797 C  CA    . GLU C 2 269  ? 147.536 133.832 178.636 1.00 67.37  ? 284  GLU C CA    1 
ATOM   11798 C  C     . GLU C 2 269  ? 148.363 134.428 177.504 1.00 67.37  ? 284  GLU C C     1 
ATOM   11799 O  O     . GLU C 2 269  ? 149.044 133.699 176.774 1.00 67.37  ? 284  GLU C O     1 
ATOM   11800 C  CB    . GLU C 2 269  ? 146.072 133.702 178.223 1.00 67.37  ? 284  GLU C CB    1 
ATOM   11801 C  CG    . GLU C 2 269  ? 145.262 132.793 179.124 1.00 67.37  ? 284  GLU C CG    1 
ATOM   11802 C  CD    . GLU C 2 269  ? 145.686 131.341 179.027 1.00 67.37  ? 284  GLU C CD    1 
ATOM   11803 O  OE1   . GLU C 2 269  ? 146.257 130.950 177.986 1.00 67.37  ? 284  GLU C OE1   1 
ATOM   11804 O  OE2   . GLU C 2 269  ? 145.449 130.588 179.994 1.00 67.37  ? 284  GLU C OE2   1 
ATOM   11805 N  N     . LEU C 2 270  ? 148.315 135.751 177.336 1.00 63.79  ? 285  LEU C N     1 
ATOM   11806 C  CA    . LEU C 2 270  ? 149.117 136.393 176.302 1.00 63.79  ? 285  LEU C CA    1 
ATOM   11807 C  C     . LEU C 2 270  ? 150.609 136.315 176.601 1.00 63.79  ? 285  LEU C C     1 
ATOM   11808 O  O     . LEU C 2 270  ? 151.422 136.458 175.683 1.00 63.79  ? 285  LEU C O     1 
ATOM   11809 C  CB    . LEU C 2 270  ? 148.688 137.854 176.137 1.00 63.79  ? 285  LEU C CB    1 
ATOM   11810 C  CG    . LEU C 2 270  ? 149.197 138.601 174.903 1.00 63.79  ? 285  LEU C CG    1 
ATOM   11811 C  CD1   . LEU C 2 270  ? 148.704 137.927 173.635 1.00 63.79  ? 285  LEU C CD1   1 
ATOM   11812 C  CD2   . LEU C 2 270  ? 148.771 140.059 174.936 1.00 63.79  ? 285  LEU C CD2   1 
ATOM   11813 N  N     . LEU C 2 271  ? 150.981 136.088 177.863 1.00 65.27  ? 286  LEU C N     1 
ATOM   11814 C  CA    . LEU C 2 271  ? 152.392 135.982 178.220 1.00 65.27  ? 286  LEU C CA    1 
ATOM   11815 C  C     . LEU C 2 271  ? 153.041 134.757 177.586 1.00 65.27  ? 286  LEU C C     1 
ATOM   11816 O  O     . LEU C 2 271  ? 154.178 134.829 177.106 1.00 65.27  ? 286  LEU C O     1 
ATOM   11817 C  CB    . LEU C 2 271  ? 152.536 135.947 179.744 1.00 65.27  ? 286  LEU C CB    1 
ATOM   11818 C  CG    . LEU C 2 271  ? 153.907 135.685 180.371 1.00 65.27  ? 286  LEU C CG    1 
ATOM   11819 C  CD1   . LEU C 2 271  ? 154.082 136.542 181.612 1.00 65.27  ? 286  LEU C CD1   1 
ATOM   11820 C  CD2   . LEU C 2 271  ? 154.074 134.214 180.725 1.00 65.27  ? 286  LEU C CD2   1 
ATOM   11821 N  N     . HIS C 2 272  ? 152.336 133.623 177.575 1.00 65.68  ? 287  HIS C N     1 
ATOM   11822 C  CA    . HIS C 2 272  ? 152.937 132.378 177.106 1.00 65.68  ? 287  HIS C CA    1 
ATOM   11823 C  C     . HIS C 2 272  ? 153.237 132.430 175.612 1.00 65.68  ? 287  HIS C C     1 
ATOM   11824 O  O     . HIS C 2 272  ? 154.341 132.078 175.180 1.00 65.68  ? 287  HIS C O     1 
ATOM   11825 C  CB    . HIS C 2 272  ? 152.020 131.199 177.428 1.00 65.68  ? 287  HIS C CB    1 
ATOM   11826 C  CG    . HIS C 2 272  ? 152.544 129.881 176.951 1.00 65.68  ? 287  HIS C CG    1 
ATOM   11827 N  ND1   . HIS C 2 272  ? 153.733 129.346 177.399 1.00 65.68  ? 287  HIS C ND1   1 
ATOM   11828 C  CD2   . HIS C 2 272  ? 152.044 128.992 176.060 1.00 65.68  ? 287  HIS C CD2   1 
ATOM   11829 C  CE1   . HIS C 2 272  ? 153.942 128.184 176.807 1.00 65.68  ? 287  HIS C CE1   1 
ATOM   11830 N  NE2   . HIS C 2 272  ? 152.932 127.946 175.990 1.00 65.68  ? 287  HIS C NE2   1 
ATOM   11831 N  N     . THR C 2 273  ? 152.266 132.864 174.806 1.00 63.52  ? 288  THR C N     1 
ATOM   11832 C  CA    . THR C 2 273  ? 152.454 132.878 173.360 1.00 63.52  ? 288  THR C CA    1 
ATOM   11833 C  C     . THR C 2 273  ? 153.473 133.916 172.912 1.00 63.52  ? 288  THR C C     1 
ATOM   11834 O  O     . THR C 2 273  ? 153.987 133.817 171.793 1.00 63.52  ? 288  THR C O     1 
ATOM   11835 C  CB    . THR C 2 273  ? 151.122 133.132 172.654 1.00 63.52  ? 288  THR C CB    1 
ATOM   11836 O  OG1   . THR C 2 273  ? 150.571 134.374 173.105 1.00 63.52  ? 288  THR C OG1   1 
ATOM   11837 C  CG2   . THR C 2 273  ? 150.143 132.012 172.953 1.00 63.52  ? 288  THR C CG2   1 
ATOM   11838 N  N     . TYR C 2 274  ? 153.774 134.906 173.749 1.00 63.54  ? 289  TYR C N     1 
ATOM   11839 C  CA    . TYR C 2 274  ? 154.755 135.945 173.436 1.00 63.54  ? 289  TYR C CA    1 
ATOM   11840 C  C     . TYR C 2 274  ? 155.737 136.052 174.593 1.00 63.54  ? 289  TYR C C     1 
ATOM   11841 O  O     . TYR C 2 274  ? 155.663 136.986 175.403 1.00 63.54  ? 289  TYR C O     1 
ATOM   11842 C  CB    . TYR C 2 274  ? 154.075 137.287 173.163 1.00 63.54  ? 289  TYR C CB    1 
ATOM   11843 C  CG    . TYR C 2 274  ? 153.293 137.336 171.871 1.00 63.54  ? 289  TYR C CG    1 
ATOM   11844 C  CD1   . TYR C 2 274  ? 152.005 136.824 171.795 1.00 63.54  ? 289  TYR C CD1   1 
ATOM   11845 C  CD2   . TYR C 2 274  ? 153.839 137.903 170.728 1.00 63.54  ? 289  TYR C CD2   1 
ATOM   11846 C  CE1   . TYR C 2 274  ? 151.286 136.870 170.617 1.00 63.54  ? 289  TYR C CE1   1 
ATOM   11847 C  CE2   . TYR C 2 274  ? 153.126 137.953 169.546 1.00 63.54  ? 289  TYR C CE2   1 
ATOM   11848 C  CZ    . TYR C 2 274  ? 151.850 137.435 169.497 1.00 63.54  ? 289  TYR C CZ    1 
ATOM   11849 O  OH    . TYR C 2 274  ? 151.135 137.482 168.323 1.00 63.54  ? 289  TYR C OH    1 
ATOM   11850 N  N     . PRO C 2 275  ? 156.674 135.108 174.707 1.00 62.65  ? 290  PRO C N     1 
ATOM   11851 C  CA    . PRO C 2 275  ? 157.686 135.189 175.765 1.00 62.65  ? 290  PRO C CA    1 
ATOM   11852 C  C     . PRO C 2 275  ? 158.788 136.199 175.492 1.00 62.65  ? 290  PRO C C     1 
ATOM   11853 O  O     . PRO C 2 275  ? 159.639 136.408 176.364 1.00 62.65  ? 290  PRO C O     1 
ATOM   11854 C  CB    . PRO C 2 275  ? 158.247 133.761 175.802 1.00 62.65  ? 290  PRO C CB    1 
ATOM   11855 C  CG    . PRO C 2 275  ? 158.117 133.292 174.397 1.00 62.65  ? 290  PRO C CG    1 
ATOM   11856 C  CD    . PRO C 2 275  ? 156.848 133.910 173.866 1.00 62.65  ? 290  PRO C CD    1 
ATOM   11857 N  N     . GLY C 2 276  ? 158.795 136.827 174.319 1.00 63.98  ? 291  GLY C N     1 
ATOM   11858 C  CA    . GLY C 2 276  ? 159.858 137.740 173.948 1.00 63.98  ? 291  GLY C CA    1 
ATOM   11859 C  C     . GLY C 2 276  ? 159.696 139.146 174.485 1.00 63.98  ? 291  GLY C C     1 
ATOM   11860 O  O     . GLY C 2 276  ? 159.371 139.338 175.661 1.00 63.98  ? 291  GLY C O     1 
ATOM   11861 N  N     . ASN C 2 277  ? 159.928 140.138 173.626 1.00 66.72  ? 292  ASN C N     1 
ATOM   11862 C  CA    . ASN C 2 277  ? 159.886 141.531 174.050 1.00 66.72  ? 292  ASN C CA    1 
ATOM   11863 C  C     . ASN C 2 277  ? 158.484 141.922 174.501 1.00 66.72  ? 292  ASN C C     1 
ATOM   11864 O  O     . ASN C 2 277  ? 157.482 141.512 173.907 1.00 66.72  ? 292  ASN C O     1 
ATOM   11865 C  CB    . ASN C 2 277  ? 160.349 142.440 172.911 1.00 66.72  ? 292  ASN C CB    1 
ATOM   11866 C  CG    . ASN C 2 277  ? 160.524 143.879 173.350 1.00 66.72  ? 292  ASN C CG    1 
ATOM   11867 O  OD1   . ASN C 2 277  ? 159.603 144.687 173.244 1.00 66.72  ? 292  ASN C OD1   1 
ATOM   11868 N  ND2   . ASN C 2 277  ? 161.709 144.205 173.850 1.00 66.72  ? 292  ASN C ND2   1 
ATOM   11869 N  N     . VAL C 2 278  ? 158.421 142.725 175.565 1.00 68.78  ? 293  VAL C N     1 
ATOM   11870 C  CA    . VAL C 2 278  ? 157.140 143.083 176.165 1.00 68.78  ? 293  VAL C CA    1 
ATOM   11871 C  C     . VAL C 2 278  ? 156.351 144.036 175.275 1.00 68.78  ? 293  VAL C C     1 
ATOM   11872 O  O     . VAL C 2 278  ? 155.116 143.975 175.235 1.00 68.78  ? 293  VAL C O     1 
ATOM   11873 C  CB    . VAL C 2 278  ? 157.363 143.678 177.568 1.00 68.78  ? 293  VAL C CB    1 
ATOM   11874 C  CG1   . VAL C 2 278  ? 156.036 143.869 178.285 1.00 68.78  ? 293  VAL C CG1   1 
ATOM   11875 C  CG2   . VAL C 2 278  ? 158.290 142.785 178.377 1.00 68.78  ? 293  VAL C CG2   1 
ATOM   11876 N  N     . SER C 2 279  ? 157.037 144.930 174.555 1.00 70.33  ? 294  SER C N     1 
ATOM   11877 C  CA    . SER C 2 279  ? 156.340 145.968 173.799 1.00 70.33  ? 294  SER C CA    1 
ATOM   11878 C  C     . SER C 2 279  ? 155.413 145.384 172.740 1.00 70.33  ? 294  SER C C     1 
ATOM   11879 O  O     . SER C 2 279  ? 154.419 146.019 172.369 1.00 70.33  ? 294  SER C O     1 
ATOM   11880 C  CB    . SER C 2 279  ? 157.351 146.916 173.151 1.00 70.33  ? 294  SER C CB    1 
ATOM   11881 O  OG    . SER C 2 279  ? 158.192 146.223 172.246 1.00 70.33  ? 294  SER C OG    1 
ATOM   11882 N  N     . THR C 2 280  ? 155.712 144.187 172.243 1.00 72.14  ? 295  THR C N     1 
ATOM   11883 C  CA    . THR C 2 280  ? 154.863 143.527 171.261 1.00 72.14  ? 295  THR C CA    1 
ATOM   11884 C  C     . THR C 2 280  ? 153.827 142.606 171.894 1.00 72.14  ? 295  THR C C     1 
ATOM   11885 O  O     . THR C 2 280  ? 153.009 142.029 171.171 1.00 72.14  ? 295  THR C O     1 
ATOM   11886 C  CB    . THR C 2 280  ? 155.717 142.730 170.270 1.00 72.14  ? 295  THR C CB    1 
ATOM   11887 O  OG1   . THR C 2 280  ? 156.513 141.774 170.980 1.00 72.14  ? 295  THR C OG1   1 
ATOM   11888 C  CG2   . THR C 2 280  ? 156.629 143.661 169.485 1.00 72.14  ? 295  THR C CG2   1 
ATOM   11889 N  N     . ILE C 2 281  ? 153.839 142.455 173.215 1.00 67.56  ? 296  ILE C N     1 
ATOM   11890 C  CA    . ILE C 2 281  ? 152.873 141.602 173.896 1.00 67.56  ? 296  ILE C CA    1 
ATOM   11891 C  C     . ILE C 2 281  ? 151.534 142.318 174.012 1.00 67.56  ? 296  ILE C C     1 
ATOM   11892 O  O     . ILE C 2 281  ? 151.376 143.233 174.821 1.00 67.56  ? 296  ILE C O     1 
ATOM   11893 C  CB    . ILE C 2 281  ? 153.381 141.176 175.283 1.00 67.56  ? 296  ILE C CB    1 
ATOM   11894 C  CG1   . ILE C 2 281  ? 154.702 140.416 175.161 1.00 67.56  ? 296  ILE C CG1   1 
ATOM   11895 C  CG2   . ILE C 2 281  ? 152.342 140.323 175.993 1.00 67.56  ? 296  ILE C CG2   1 
ATOM   11896 C  CD1   . ILE C 2 281  ? 155.273 139.973 176.491 1.00 67.56  ? 296  ILE C CD1   1 
ATOM   11897 N  N     . ASP C 2 285  ? 144.141 151.625 175.227 1.00 68.10  ? 300  ASP C N     1 
ATOM   11898 C  CA    . ASP C 2 285  ? 143.735 152.099 176.544 1.00 68.10  ? 300  ASP C CA    1 
ATOM   11899 C  C     . ASP C 2 285  ? 144.191 153.539 176.753 1.00 68.10  ? 300  ASP C C     1 
ATOM   11900 O  O     . ASP C 2 285  ? 145.177 153.793 177.445 1.00 68.10  ? 300  ASP C O     1 
ATOM   11901 C  CB    . ASP C 2 285  ? 144.305 151.194 177.639 1.00 68.10  ? 300  ASP C CB    1 
ATOM   11902 C  CG    . ASP C 2 285  ? 143.675 151.448 178.995 1.00 68.10  ? 300  ASP C CG    1 
ATOM   11903 O  OD1   . ASP C 2 285  ? 142.788 152.321 179.091 1.00 68.10  ? 300  ASP C OD1   1 
ATOM   11904 O  OD2   . ASP C 2 285  ? 144.066 150.770 179.967 1.00 68.10  ? 300  ASP C OD2   1 
ATOM   11905 N  N     . GLY C 2 286  ? 143.457 154.478 176.162 1.00 67.12  ? 301  GLY C N     1 
ATOM   11906 C  CA    . GLY C 2 286  ? 143.864 155.872 176.231 1.00 67.12  ? 301  GLY C CA    1 
ATOM   11907 C  C     . GLY C 2 286  ? 145.205 156.067 175.556 1.00 67.12  ? 301  GLY C C     1 
ATOM   11908 O  O     . GLY C 2 286  ? 145.417 155.652 174.411 1.00 67.12  ? 301  GLY C O     1 
ATOM   11909 N  N     . ARG C 2 287  ? 146.131 156.708 176.267 1.00 73.24  ? 302  ARG C N     1 
ATOM   11910 C  CA    . ARG C 2 287  ? 147.483 156.882 175.753 1.00 73.24  ? 302  ARG C CA    1 
ATOM   11911 C  C     . ARG C 2 287  ? 148.439 155.810 176.255 1.00 73.24  ? 302  ARG C C     1 
ATOM   11912 O  O     . ARG C 2 287  ? 149.365 155.428 175.529 1.00 73.24  ? 302  ARG C O     1 
ATOM   11913 C  CB    . ARG C 2 287  ? 148.016 158.270 176.122 1.00 73.24  ? 302  ARG C CB    1 
ATOM   11914 C  CG    . ARG C 2 287  ? 149.357 158.608 175.487 1.00 73.24  ? 302  ARG C CG    1 
ATOM   11915 C  CD    . ARG C 2 287  ? 149.657 160.094 175.577 1.00 73.24  ? 302  ARG C CD    1 
ATOM   11916 N  NE    . ARG C 2 287  ? 148.686 160.889 174.834 1.00 73.24  ? 302  ARG C NE    1 
ATOM   11917 C  CZ    . ARG C 2 287  ? 148.785 161.177 173.543 1.00 73.24  ? 302  ARG C CZ    1 
ATOM   11918 N  NH1   . ARG C 2 287  ? 149.803 160.750 172.816 1.00 73.24  ? 302  ARG C NH1   1 
ATOM   11919 N  NH2   . ARG C 2 287  ? 147.837 161.912 172.968 1.00 73.24  ? 302  ARG C NH2   1 
ATOM   11920 N  N     . LYS C 2 288  ? 148.236 155.311 177.471 1.00 74.23  ? 303  LYS C N     1 
ATOM   11921 C  CA    . LYS C 2 288  ? 149.077 154.245 177.988 1.00 74.23  ? 303  LYS C CA    1 
ATOM   11922 C  C     . LYS C 2 288  ? 148.769 152.929 177.278 1.00 74.23  ? 303  LYS C C     1 
ATOM   11923 O  O     . LYS C 2 288  ? 147.685 152.726 176.724 1.00 74.23  ? 303  LYS C O     1 
ATOM   11924 C  CB    . LYS C 2 288  ? 148.881 154.081 179.495 1.00 74.23  ? 303  LYS C CB    1 
ATOM   11925 C  CG    . LYS C 2 288  ? 147.527 153.509 179.886 1.00 74.23  ? 303  LYS C CG    1 
ATOM   11926 C  CD    . LYS C 2 288  ? 147.481 153.161 181.365 1.00 74.23  ? 303  LYS C CD    1 
ATOM   11927 C  CE    . LYS C 2 288  ? 146.160 152.507 181.738 1.00 74.23  ? 303  LYS C CE    1 
ATOM   11928 N  NZ    . LYS C 2 288  ? 146.131 152.075 183.163 1.00 74.23  ? 303  LYS C NZ    1 
ATOM   11929 N  N     . ASN C 2 289  ? 149.748 152.029 177.296 1.00 66.79  ? 304  ASN C N     1 
ATOM   11930 C  CA    . ASN C 2 289  ? 149.621 150.711 176.692 1.00 66.79  ? 304  ASN C CA    1 
ATOM   11931 C  C     . ASN C 2 289  ? 149.866 149.650 177.754 1.00 66.79  ? 304  ASN C C     1 
ATOM   11932 O  O     . ASN C 2 289  ? 150.877 149.695 178.461 1.00 66.79  ? 304  ASN C O     1 
ATOM   11933 C  CB    . ASN C 2 289  ? 150.602 150.540 175.529 1.00 66.79  ? 304  ASN C CB    1 
ATOM   11934 C  CG    . ASN C 2 289  ? 150.344 151.519 174.401 1.00 66.79  ? 304  ASN C CG    1 
ATOM   11935 O  OD1   . ASN C 2 289  ? 149.199 151.867 174.114 1.00 66.79  ? 304  ASN C OD1   1 
ATOM   11936 N  ND2   . ASN C 2 289  ? 151.413 151.972 173.755 1.00 66.79  ? 304  ASN C ND2   1 
ATOM   11937 N  N     . VAL C 2 290  ? 148.939 148.698 177.861 1.00 60.55  ? 305  VAL C N     1 
ATOM   11938 C  CA    . VAL C 2 290  ? 149.030 147.622 178.836 1.00 60.55  ? 305  VAL C CA    1 
ATOM   11939 C  C     . VAL C 2 290  ? 148.740 146.304 178.130 1.00 60.55  ? 305  VAL C C     1 
ATOM   11940 O  O     . VAL C 2 290  ? 148.105 146.262 177.074 1.00 60.55  ? 305  VAL C O     1 
ATOM   11941 C  CB    . VAL C 2 290  ? 148.061 147.829 180.025 1.00 60.55  ? 305  VAL C CB    1 
ATOM   11942 C  CG1   . VAL C 2 290  ? 146.637 147.457 179.635 1.00 60.55  ? 305  VAL C CG1   1 
ATOM   11943 C  CG2   . VAL C 2 290  ? 148.522 147.045 181.249 1.00 60.55  ? 305  VAL C CG2   1 
ATOM   11944 N  N     . VAL C 2 291  ? 149.232 145.220 178.723 1.00 63.20  ? 306  VAL C N     1 
ATOM   11945 C  CA    . VAL C 2 291  ? 148.932 143.879 178.233 1.00 63.20  ? 306  VAL C CA    1 
ATOM   11946 C  C     . VAL C 2 291  ? 147.472 143.597 178.562 1.00 63.20  ? 306  VAL C C     1 
ATOM   11947 O  O     . VAL C 2 291  ? 147.088 143.627 179.741 1.00 63.20  ? 306  VAL C O     1 
ATOM   11948 C  CB    . VAL C 2 291  ? 149.868 142.830 178.851 1.00 63.20  ? 306  VAL C CB    1 
ATOM   11949 C  CG1   . VAL C 2 291  ? 149.565 141.452 178.287 1.00 63.20  ? 306  VAL C CG1   1 
ATOM   11950 C  CG2   . VAL C 2 291  ? 151.319 143.206 178.600 1.00 63.20  ? 306  VAL C CG2   1 
ATOM   11951 N  N     . PRO C 2 292  ? 146.630 143.325 177.567 1.00 57.92  ? 307  PRO C N     1 
ATOM   11952 C  CA    . PRO C 2 292  ? 145.191 143.236 177.828 1.00 57.92  ? 307  PRO C CA    1 
ATOM   11953 C  C     . PRO C 2 292  ? 144.849 142.081 178.753 1.00 57.92  ? 307  PRO C C     1 
ATOM   11954 O  O     . PRO C 2 292  ? 145.499 141.034 178.747 1.00 57.92  ? 307  PRO C O     1 
ATOM   11955 C  CB    . PRO C 2 292  ? 144.592 143.028 176.433 1.00 57.92  ? 307  PRO C CB    1 
ATOM   11956 C  CG    . PRO C 2 292  ? 145.696 142.421 175.639 1.00 57.92  ? 307  PRO C CG    1 
ATOM   11957 C  CD    . PRO C 2 292  ? 146.955 143.050 176.158 1.00 57.92  ? 307  PRO C CD    1 
ATOM   11958 N  N     . CYS C 2 293  ? 143.812 142.291 179.563 1.00 61.52  ? 308  CYS C N     1 
ATOM   11959 C  CA    . CYS C 2 293  ? 143.261 141.239 180.414 1.00 61.52  ? 308  CYS C CA    1 
ATOM   11960 C  C     . CYS C 2 293  ? 142.379 140.358 179.538 1.00 61.52  ? 308  CYS C C     1 
ATOM   11961 O  O     . CYS C 2 293  ? 141.148 140.440 179.546 1.00 61.52  ? 308  CYS C O     1 
ATOM   11962 C  CB    . CYS C 2 293  ? 142.489 141.835 181.584 1.00 61.52  ? 308  CYS C CB    1 
ATOM   11963 S  SG    . CYS C 2 293  ? 141.803 140.615 182.722 1.00 61.52  ? 308  CYS C SG    1 
ATOM   11964 N  N     . VAL C 2 294  ? 143.042 139.503 178.758 1.00 58.07  ? 309  VAL C N     1 
ATOM   11965 C  CA    . VAL C 2 294  ? 142.360 138.701 177.748 1.00 58.07  ? 309  VAL C CA    1 
ATOM   11966 C  C     . VAL C 2 294  ? 141.296 137.842 178.413 1.00 58.07  ? 309  VAL C C     1 
ATOM   11967 O  O     . VAL C 2 294  ? 141.602 136.973 179.238 1.00 58.07  ? 309  VAL C O     1 
ATOM   11968 C  CB    . VAL C 2 294  ? 143.368 137.840 176.980 1.00 58.07  ? 309  VAL C CB    1 
ATOM   11969 C  CG1   . VAL C 2 294  ? 142.648 136.899 176.026 1.00 58.07  ? 309  VAL C CG1   1 
ATOM   11970 C  CG2   . VAL C 2 294  ? 144.352 138.720 176.230 1.00 58.07  ? 309  VAL C CG2   1 
ATOM   11971 N  N     . LEU C 2 295  ? 140.040 138.083 178.054 1.00 46.59  ? 310  LEU C N     1 
ATOM   11972 C  CA    . LEU C 2 295  ? 138.929 137.244 178.471 1.00 46.59  ? 310  LEU C CA    1 
ATOM   11973 C  C     . LEU C 2 295  ? 138.356 136.545 177.247 1.00 46.59  ? 310  LEU C C     1 
ATOM   11974 O  O     . LEU C 2 295  ? 138.303 137.114 176.154 1.00 46.59  ? 310  LEU C O     1 
ATOM   11975 C  CB    . LEU C 2 295  ? 137.848 138.059 179.196 1.00 46.59  ? 310  LEU C CB    1 
ATOM   11976 C  CG    . LEU C 2 295  ? 136.831 138.926 178.449 1.00 46.59  ? 310  LEU C CG    1 
ATOM   11977 C  CD1   . LEU C 2 295  ? 135.542 138.160 178.186 1.00 46.59  ? 310  LEU C CD1   1 
ATOM   11978 C  CD2   . LEU C 2 295  ? 136.542 140.189 179.240 1.00 46.59  ? 310  LEU C CD2   1 
ATOM   11979 N  N     . SER C 2 296  ? 137.940 135.299 177.435 1.00 39.84  ? 311  SER C N     1 
ATOM   11980 C  CA    . SER C 2 296  ? 137.559 134.428 176.334 1.00 39.84  ? 311  SER C CA    1 
ATOM   11981 C  C     . SER C 2 296  ? 136.072 134.121 176.408 1.00 39.84  ? 311  SER C C     1 
ATOM   11982 O  O     . SER C 2 296  ? 135.581 133.651 177.439 1.00 39.84  ? 311  SER C O     1 
ATOM   11983 C  CB    . SER C 2 296  ? 138.368 133.130 176.363 1.00 39.84  ? 311  SER C CB    1 
ATOM   11984 O  OG    . SER C 2 296  ? 138.039 132.300 175.263 1.00 39.84  ? 311  SER C OG    1 
ATOM   11985 N  N     . VAL C 2 297  ? 135.365 134.386 175.318 1.00 36.88  ? 312  VAL C N     1 
ATOM   11986 C  CA    . VAL C 2 297  ? 133.956 134.042 175.181 1.00 36.88  ? 312  VAL C CA    1 
ATOM   11987 C  C     . VAL C 2 297  ? 133.874 132.941 174.135 1.00 36.88  ? 312  VAL C C     1 
ATOM   11988 O  O     . VAL C 2 297  ? 134.146 133.178 172.952 1.00 36.88  ? 312  VAL C O     1 
ATOM   11989 C  CB    . VAL C 2 297  ? 133.109 135.257 174.782 1.00 36.88  ? 312  VAL C CB    1 
ATOM   11990 C  CG1   . VAL C 2 297  ? 131.635 134.956 174.962 1.00 36.88  ? 312  VAL C CG1   1 
ATOM   11991 C  CG2   . VAL C 2 297  ? 133.514 136.479 175.589 1.00 36.88  ? 312  VAL C CG2   1 
ATOM   11992 N  N     . SER C 2 298  ? 133.505 131.735 174.560 1.00 36.57  ? 313  SER C N     1 
ATOM   11993 C  CA    . SER C 2 298  ? 133.454 130.581 173.673 1.00 36.57  ? 313  SER C CA    1 
ATOM   11994 C  C     . SER C 2 298  ? 132.084 129.931 173.765 1.00 36.57  ? 313  SER C C     1 
ATOM   11995 O  O     . SER C 2 298  ? 131.636 129.573 174.858 1.00 36.57  ? 313  SER C O     1 
ATOM   11996 C  CB    . SER C 2 298  ? 134.538 129.560 174.026 1.00 36.57  ? 313  SER C CB    1 
ATOM   11997 O  OG    . SER C 2 298  ? 134.255 128.932 175.263 1.00 36.57  ? 313  SER C OG    1 
ATOM   11998 N  N     . GLY C 2 299  ? 131.430 129.769 172.620 1.00 32.77  ? 314  GLY C N     1 
ATOM   11999 C  CA    . GLY C 2 299  ? 130.117 129.162 172.561 1.00 32.77  ? 314  GLY C CA    1 
ATOM   12000 C  C     . GLY C 2 299  ? 130.128 127.937 171.669 1.00 32.77  ? 314  GLY C C     1 
ATOM   12001 O  O     . GLY C 2 299  ? 130.861 127.875 170.682 1.00 32.77  ? 314  GLY C O     1 
ATOM   12002 N  N     . ASP C 2 300  ? 129.305 126.957 172.027 1.00 37.93  ? 315  ASP C N     1 
ATOM   12003 C  CA    . ASP C 2 300  ? 129.200 125.702 171.288 1.00 37.93  ? 315  ASP C CA    1 
ATOM   12004 C  C     . ASP C 2 300  ? 128.011 125.821 170.344 1.00 37.93  ? 315  ASP C C     1 
ATOM   12005 O  O     . ASP C 2 300  ? 126.860 125.665 170.757 1.00 37.93  ? 315  ASP C O     1 
ATOM   12006 C  CB    . ASP C 2 300  ? 129.041 124.523 172.243 1.00 37.93  ? 315  ASP C CB    1 
ATOM   12007 C  CG    . ASP C 2 300  ? 129.231 123.180 171.557 1.00 37.93  ? 315  ASP C CG    1 
ATOM   12008 O  OD1   . ASP C 2 300  ? 129.151 123.118 170.313 1.00 37.93  ? 315  ASP C OD1   1 
ATOM   12009 O  OD2   . ASP C 2 300  ? 129.458 122.179 172.270 1.00 37.93  ? 315  ASP C OD2   1 
ATOM   12010 N  N     . VAL C 2 301  ? 128.288 126.096 169.068 1.00 37.58  ? 316  VAL C N     1 
ATOM   12011 C  CA    . VAL C 2 301  ? 127.195 126.234 168.114 1.00 37.58  ? 316  VAL C CA    1 
ATOM   12012 C  C     . VAL C 2 301  ? 126.600 124.888 167.730 1.00 37.58  ? 316  VAL C C     1 
ATOM   12013 O  O     . VAL C 2 301  ? 125.486 124.848 167.199 1.00 37.58  ? 316  VAL C O     1 
ATOM   12014 C  CB    . VAL C 2 301  ? 127.633 126.996 166.851 1.00 37.58  ? 316  VAL C CB    1 
ATOM   12015 C  CG1   . VAL C 2 301  ? 128.337 128.284 167.232 1.00 37.58  ? 316  VAL C CG1   1 
ATOM   12016 C  CG2   . VAL C 2 301  ? 128.509 126.130 165.980 1.00 37.58  ? 316  VAL C CG2   1 
ATOM   12017 N  N     . ASP C 2 302  ? 127.296 123.780 167.995 1.00 43.10  ? 317  ASP C N     1 
ATOM   12018 C  CA    . ASP C 2 302  ? 126.674 122.470 167.828 1.00 43.10  ? 317  ASP C CA    1 
ATOM   12019 C  C     . ASP C 2 302  ? 125.684 122.200 168.954 1.00 43.10  ? 317  ASP C C     1 
ATOM   12020 O  O     . ASP C 2 302  ? 124.514 121.876 168.710 1.00 43.10  ? 317  ASP C O     1 
ATOM   12021 C  CB    . ASP C 2 302  ? 127.744 121.381 167.778 1.00 43.10  ? 317  ASP C CB    1 
ATOM   12022 C  CG    . ASP C 2 302  ? 128.719 121.574 166.637 1.00 43.10  ? 317  ASP C CG    1 
ATOM   12023 O  OD1   . ASP C 2 302  ? 128.323 122.162 165.611 1.00 43.10  ? 317  ASP C OD1   1 
ATOM   12024 O  OD2   . ASP C 2 302  ? 129.882 121.139 166.764 1.00 43.10  ? 317  ASP C OD2   1 
ATOM   12025 N  N     . LEU C 2 303  ? 126.134 122.352 170.200 1.00 39.22  ? 318  LEU C N     1 
ATOM   12026 C  CA    . LEU C 2 303  ? 125.215 122.273 171.326 1.00 39.22  ? 318  LEU C CA    1 
ATOM   12027 C  C     . LEU C 2 303  ? 124.204 123.409 171.293 1.00 39.22  ? 318  LEU C C     1 
ATOM   12028 O  O     . LEU C 2 303  ? 123.068 123.238 171.741 1.00 39.22  ? 318  LEU C O     1 
ATOM   12029 C  CB    . LEU C 2 303  ? 125.993 122.281 172.641 1.00 39.22  ? 318  LEU C CB    1 
ATOM   12030 C  CG    . LEU C 2 303  ? 125.208 121.931 173.904 1.00 39.22  ? 318  LEU C CG    1 
ATOM   12031 C  CD1   . LEU C 2 303  ? 124.481 120.611 173.723 1.00 39.22  ? 318  LEU C CD1   1 
ATOM   12032 C  CD2   . LEU C 2 303  ? 126.144 121.867 175.096 1.00 39.22  ? 318  LEU C CD2   1 
ATOM   12033 N  N     . GLY C 2 304  ? 124.591 124.570 170.759 1.00 37.58  ? 319  GLY C N     1 
ATOM   12034 C  CA    . GLY C 2 304  ? 123.631 125.649 170.591 1.00 37.58  ? 319  GLY C CA    1 
ATOM   12035 C  C     . GLY C 2 304  ? 122.546 125.313 169.586 1.00 37.58  ? 319  GLY C C     1 
ATOM   12036 O  O     . GLY C 2 304  ? 121.372 125.624 169.800 1.00 37.58  ? 319  GLY C O     1 
ATOM   12037 N  N     . THR C 2 305  ? 122.925 124.683 168.473 1.00 40.13  ? 320  THR C N     1 
ATOM   12038 C  CA    . THR C 2 305  ? 121.938 124.221 167.507 1.00 40.13  ? 320  THR C CA    1 
ATOM   12039 C  C     . THR C 2 305  ? 121.034 123.162 168.120 1.00 40.13  ? 320  THR C C     1 
ATOM   12040 O  O     . THR C 2 305  ? 119.825 123.141 167.865 1.00 40.13  ? 320  THR C O     1 
ATOM   12041 C  CB    . THR C 2 305  ? 122.642 123.680 166.264 1.00 40.13  ? 320  THR C CB    1 
ATOM   12042 O  OG1   . THR C 2 305  ? 123.535 124.676 165.751 1.00 40.13  ? 320  THR C OG1   1 
ATOM   12043 C  CG2   . THR C 2 305  ? 121.634 123.322 165.193 1.00 40.13  ? 320  THR C CG2   1 
ATOM   12044 N  N     . LEU C 2 306  ? 121.603 122.278 168.943 1.00 42.93  ? 321  LEU C N     1 
ATOM   12045 C  CA    . LEU C 2 306  ? 120.782 121.311 169.667 1.00 42.93  ? 321  LEU C CA    1 
ATOM   12046 C  C     . LEU C 2 306  ? 119.799 122.012 170.599 1.00 42.93  ? 321  LEU C C     1 
ATOM   12047 O  O     . LEU C 2 306  ? 118.630 121.618 170.698 1.00 42.93  ? 321  LEU C O     1 
ATOM   12048 C  CB    . LEU C 2 306  ? 121.675 120.353 170.455 1.00 42.93  ? 321  LEU C CB    1 
ATOM   12049 C  CG    . LEU C 2 306  ? 121.600 118.875 170.078 1.00 42.93  ? 321  LEU C CG    1 
ATOM   12050 C  CD1   . LEU C 2 306  ? 122.422 118.032 171.040 1.00 42.93  ? 321  LEU C CD1   1 
ATOM   12051 C  CD2   . LEU C 2 306  ? 120.157 118.411 170.053 1.00 42.93  ? 321  LEU C CD2   1 
ATOM   12052 N  N     . ALA C 2 307  ? 120.261 123.053 171.295 1.00 43.03  ? 322  ALA C N     1 
ATOM   12053 C  CA    . ALA C 2 307  ? 119.391 123.807 172.190 1.00 43.03  ? 322  ALA C CA    1 
ATOM   12054 C  C     . ALA C 2 307  ? 118.262 124.477 171.425 1.00 43.03  ? 322  ALA C C     1 
ATOM   12055 O  O     . ALA C 2 307  ? 117.116 124.487 171.882 1.00 43.03  ? 322  ALA C O     1 
ATOM   12056 C  CB    . ALA C 2 307  ? 120.203 124.848 172.957 1.00 43.03  ? 322  ALA C CB    1 
ATOM   12057 N  N     . TYR C 2 308  ? 118.570 125.056 170.265 1.00 38.22  ? 323  TYR C N     1 
ATOM   12058 C  CA    . TYR C 2 308  ? 117.538 125.726 169.481 1.00 38.22  ? 323  TYR C CA    1 
ATOM   12059 C  C     . TYR C 2 308  ? 116.590 124.733 168.826 1.00 38.22  ? 323  TYR C C     1 
ATOM   12060 O  O     . TYR C 2 308  ? 115.442 125.079 168.532 1.00 38.22  ? 323  TYR C O     1 
ATOM   12061 C  CB    . TYR C 2 308  ? 118.178 126.631 168.431 1.00 38.22  ? 323  TYR C CB    1 
ATOM   12062 C  CG    . TYR C 2 308  ? 118.509 127.998 168.968 1.00 38.22  ? 323  TYR C CG    1 
ATOM   12063 C  CD1   . TYR C 2 308  ? 117.764 128.552 169.993 1.00 38.22  ? 323  TYR C CD1   1 
ATOM   12064 C  CD2   . TYR C 2 308  ? 119.566 128.729 168.460 1.00 38.22  ? 323  TYR C CD2   1 
ATOM   12065 C  CE1   . TYR C 2 308  ? 118.057 129.797 170.493 1.00 38.22  ? 323  TYR C CE1   1 
ATOM   12066 C  CE2   . TYR C 2 308  ? 119.867 129.976 168.956 1.00 38.22  ? 323  TYR C CE2   1 
ATOM   12067 C  CZ    . TYR C 2 308  ? 119.110 130.504 169.971 1.00 38.22  ? 323  TYR C CZ    1 
ATOM   12068 O  OH    . TYR C 2 308  ? 119.407 131.750 170.466 1.00 38.22  ? 323  TYR C OH    1 
ATOM   12069 N  N     . LEU C 2 309  ? 117.047 123.505 168.582 1.00 47.91  ? 324  LEU C N     1 
ATOM   12070 C  CA    . LEU C 2 309  ? 116.140 122.475 168.090 1.00 47.91  ? 324  LEU C CA    1 
ATOM   12071 C  C     . LEU C 2 309  ? 115.220 121.978 169.198 1.00 47.91  ? 324  LEU C C     1 
ATOM   12072 O  O     . LEU C 2 309  ? 114.052 121.661 168.948 1.00 47.91  ? 324  LEU C O     1 
ATOM   12073 C  CB    . LEU C 2 309  ? 116.937 121.319 167.487 1.00 47.91  ? 324  LEU C CB    1 
ATOM   12074 C  CG    . LEU C 2 309  ? 117.483 121.530 166.074 1.00 47.91  ? 324  LEU C CG    1 
ATOM   12075 C  CD1   . LEU C 2 309  ? 118.449 120.420 165.694 1.00 47.91  ? 324  LEU C CD1   1 
ATOM   12076 C  CD2   . LEU C 2 309  ? 116.335 121.597 165.083 1.00 47.91  ? 324  LEU C CD2   1 
ATOM   12077 N  N     . TYR C 2 310  ? 115.732 121.895 170.428 1.00 52.76  ? 325  TYR C N     1 
ATOM   12078 C  CA    . TYR C 2 310  ? 114.890 121.495 171.553 1.00 52.76  ? 325  TYR C CA    1 
ATOM   12079 C  C     . TYR C 2 310  ? 113.886 122.585 171.908 1.00 52.76  ? 325  TYR C C     1 
ATOM   12080 O  O     . TYR C 2 310  ? 112.694 122.313 172.095 1.00 52.76  ? 325  TYR C O     1 
ATOM   12081 C  CB    . TYR C 2 310  ? 115.758 121.153 172.767 1.00 52.76  ? 325  TYR C CB    1 
ATOM   12082 C  CG    . TYR C 2 310  ? 116.182 119.705 172.834 1.00 52.76  ? 325  TYR C CG    1 
ATOM   12083 C  CD1   . TYR C 2 310  ? 115.259 118.707 173.102 1.00 52.76  ? 325  TYR C CD1   1 
ATOM   12084 C  CD2   . TYR C 2 310  ? 117.505 119.337 172.641 1.00 52.76  ? 325  TYR C CD2   1 
ATOM   12085 C  CE1   . TYR C 2 310  ? 115.636 117.382 173.166 1.00 52.76  ? 325  TYR C CE1   1 
ATOM   12086 C  CE2   . TYR C 2 310  ? 117.893 118.013 172.706 1.00 52.76  ? 325  TYR C CE2   1 
ATOM   12087 C  CZ    . TYR C 2 310  ? 116.954 117.041 172.968 1.00 52.76  ? 325  TYR C CZ    1 
ATOM   12088 O  OH    . TYR C 2 310  ? 117.333 115.721 173.033 1.00 52.76  ? 325  TYR C OH    1 
ATOM   12089 N  N     . ASP C 2 311  ? 114.357 123.828 172.008 1.00 55.95  ? 326  ASP C N     1 
ATOM   12090 C  CA    . ASP C 2 311  ? 113.516 124.931 172.458 1.00 55.95  ? 326  ASP C CA    1 
ATOM   12091 C  C     . ASP C 2 311  ? 112.399 125.232 171.468 1.00 55.95  ? 326  ASP C C     1 
ATOM   12092 O  O     . ASP C 2 311  ? 111.257 125.481 171.870 1.00 55.95  ? 326  ASP C O     1 
ATOM   12093 C  CB    . ASP C 2 311  ? 114.378 126.172 172.684 1.00 55.95  ? 326  ASP C CB    1 
ATOM   12094 C  CG    . ASP C 2 311  ? 113.574 127.449 172.658 1.00 55.95  ? 326  ASP C CG    1 
ATOM   12095 O  OD1   . ASP C 2 311  ? 112.771 127.668 173.588 1.00 55.95  ? 326  ASP C OD1   1 
ATOM   12096 O  OD2   . ASP C 2 311  ? 113.745 128.234 171.703 1.00 55.95  ? 326  ASP C OD2   1 
ATOM   12097 N  N     . SER C 2 312  ? 112.708 125.214 170.172 1.00 54.88  ? 327  SER C N     1 
ATOM   12098 C  CA    . SER C 2 312  ? 111.725 125.579 169.163 1.00 54.88  ? 327  SER C CA    1 
ATOM   12099 C  C     . SER C 2 312  ? 110.590 124.573 169.047 1.00 54.88  ? 327  SER C C     1 
ATOM   12100 O  O     . SER C 2 312  ? 109.569 124.891 168.429 1.00 54.88  ? 327  SER C O     1 
ATOM   12101 C  CB    . SER C 2 312  ? 112.412 125.745 167.809 1.00 54.88  ? 327  SER C CB    1 
ATOM   12102 O  OG    . SER C 2 312  ? 113.443 126.713 167.885 1.00 54.88  ? 327  SER C OG    1 
ATOM   12103 N  N     . PHE C 2 313  ? 110.735 123.384 169.618 1.00 64.56  ? 328  PHE C N     1 
ATOM   12104 C  CA    . PHE C 2 313  ? 109.686 122.377 169.549 1.00 64.56  ? 328  PHE C CA    1 
ATOM   12105 C  C     . PHE C 2 313  ? 108.472 122.800 170.370 1.00 64.56  ? 328  PHE C C     1 
ATOM   12106 O  O     . PHE C 2 313  ? 107.384 122.999 169.829 1.00 64.56  ? 328  PHE C O     1 
ATOM   12107 C  CB    . PHE C 2 313  ? 110.212 121.025 170.031 1.00 64.56  ? 328  PHE C CB    1 
ATOM   12108 C  CG    . PHE C 2 313  ? 109.207 119.914 169.932 1.00 64.56  ? 328  PHE C CG    1 
ATOM   12109 C  CD1   . PHE C 2 313  ? 109.002 119.254 168.732 1.00 64.56  ? 328  PHE C CD1   1 
ATOM   12110 C  CD2   . PHE C 2 313  ? 108.472 119.525 171.039 1.00 64.56  ? 328  PHE C CD2   1 
ATOM   12111 C  CE1   . PHE C 2 313  ? 108.080 118.230 168.636 1.00 64.56  ? 328  PHE C CE1   1 
ATOM   12112 C  CE2   . PHE C 2 313  ? 107.548 118.502 170.949 1.00 64.56  ? 328  PHE C CE2   1 
ATOM   12113 C  CZ    . PHE C 2 313  ? 107.352 117.853 169.746 1.00 64.56  ? 328  PHE C CZ    1 
ATOM   12114 N  N     . VAL C 2 330  ? 105.440 120.277 165.271 1.00 55.13  ? 345  VAL C N     1 
ATOM   12115 C  CA    . VAL C 2 330  ? 105.743 121.475 164.506 1.00 55.13  ? 345  VAL C CA    1 
ATOM   12116 C  C     . VAL C 2 330  ? 106.883 122.267 165.127 1.00 55.13  ? 345  VAL C C     1 
ATOM   12117 O  O     . VAL C 2 330  ? 106.799 122.691 166.275 1.00 55.13  ? 345  VAL C O     1 
ATOM   12118 C  CB    . VAL C 2 330  ? 104.508 122.381 164.393 1.00 55.13  ? 345  VAL C CB    1 
ATOM   12119 C  CG1   . VAL C 2 330  ? 103.822 122.527 165.743 1.00 55.13  ? 345  VAL C CG1   1 
ATOM   12120 C  CG2   . VAL C 2 330  ? 104.892 123.736 163.818 1.00 55.13  ? 345  VAL C CG2   1 
ATOM   12121 N  N     . LEU C 2 331  ? 107.953 122.466 164.372 1.00 57.76  ? 346  LEU C N     1 
ATOM   12122 C  CA    . LEU C 2 331  ? 109.090 123.218 164.884 1.00 57.76  ? 346  LEU C CA    1 
ATOM   12123 C  C     . LEU C 2 331  ? 108.941 124.681 164.490 1.00 57.76  ? 346  LEU C C     1 
ATOM   12124 O  O     . LEU C 2 331  ? 108.966 125.012 163.300 1.00 57.76  ? 346  LEU C O     1 
ATOM   12125 C  CB    . LEU C 2 331  ? 110.404 122.652 164.346 1.00 57.76  ? 346  LEU C CB    1 
ATOM   12126 C  CG    . LEU C 2 331  ? 110.792 121.235 164.765 1.00 57.76  ? 346  LEU C CG    1 
ATOM   12127 C  CD1   . LEU C 2 331  ? 112.159 120.873 164.209 1.00 57.76  ? 346  LEU C CD1   1 
ATOM   12128 C  CD2   . LEU C 2 331  ? 110.778 121.105 166.275 1.00 57.76  ? 346  LEU C CD2   1 
ATOM   12129 N  N     . LYS C 2 332  ? 108.791 125.551 165.485 1.00 52.68  ? 347  LYS C N     1 
ATOM   12130 C  CA    . LYS C 2 332  ? 108.660 126.987 165.243 1.00 52.68  ? 347  LYS C CA    1 
ATOM   12131 C  C     . LYS C 2 332  ? 110.012 127.674 165.427 1.00 52.68  ? 347  LYS C C     1 
ATOM   12132 O  O     . LYS C 2 332  ? 110.225 128.480 166.332 1.00 52.68  ? 347  LYS C O     1 
ATOM   12133 C  CB    . LYS C 2 332  ? 107.598 127.586 166.157 1.00 52.68  ? 347  LYS C CB    1 
ATOM   12134 C  CG    . LYS C 2 332  ? 106.177 127.410 165.661 1.00 52.68  ? 347  LYS C CG    1 
ATOM   12135 C  CD    . LYS C 2 332  ? 105.216 128.253 166.477 1.00 52.68  ? 347  LYS C CD    1 
ATOM   12136 C  CE    . LYS C 2 332  ? 103.819 128.225 165.885 1.00 52.68  ? 347  LYS C CE    1 
ATOM   12137 N  NZ    . LYS C 2 332  ? 102.890 129.119 166.627 1.00 52.68  ? 347  LYS C NZ    1 
ATOM   12138 N  N     . LEU C 2 333  ? 110.936 127.336 164.534 1.00 45.70  ? 348  LEU C N     1 
ATOM   12139 C  CA    . LEU C 2 333  ? 112.238 127.980 164.543 1.00 45.70  ? 348  LEU C CA    1 
ATOM   12140 C  C     . LEU C 2 333  ? 112.112 129.448 164.147 1.00 45.70  ? 348  LEU C C     1 
ATOM   12141 O  O     . LEU C 2 333  ? 111.135 129.874 163.526 1.00 45.70  ? 348  LEU C O     1 
ATOM   12142 C  CB    . LEU C 2 333  ? 113.204 127.268 163.597 1.00 45.70  ? 348  LEU C CB    1 
ATOM   12143 C  CG    . LEU C 2 333  ? 114.026 126.098 164.143 1.00 45.70  ? 348  LEU C CG    1 
ATOM   12144 C  CD1   . LEU C 2 333  ? 113.156 124.892 164.414 1.00 45.70  ? 348  LEU C CD1   1 
ATOM   12145 C  CD2   . LEU C 2 333  ? 115.134 125.745 163.174 1.00 45.70  ? 348  LEU C CD2   1 
ATOM   12146 N  N     . HIS C 2 334  ? 113.122 130.226 164.520 1.00 35.77  ? 349  HIS C N     1 
ATOM   12147 C  CA    . HIS C 2 334  ? 113.125 131.645 164.217 1.00 35.77  ? 349  HIS C CA    1 
ATOM   12148 C  C     . HIS C 2 334  ? 113.259 131.868 162.710 1.00 35.77  ? 349  HIS C C     1 
ATOM   12149 O  O     . HIS C 2 334  ? 113.934 131.100 162.019 1.00 35.77  ? 349  HIS C O     1 
ATOM   12150 C  CB    . HIS C 2 334  ? 114.269 132.335 164.953 1.00 35.77  ? 349  HIS C CB    1 
ATOM   12151 C  CG    . HIS C 2 334  ? 114.156 133.826 164.999 1.00 35.77  ? 349  HIS C CG    1 
ATOM   12152 N  ND1   . HIS C 2 334  ? 115.014 134.659 164.316 1.00 35.77  ? 349  HIS C ND1   1 
ATOM   12153 C  CD2   . HIS C 2 334  ? 113.292 134.634 165.658 1.00 35.77  ? 349  HIS C CD2   1 
ATOM   12154 C  CE1   . HIS C 2 334  ? 114.682 135.916 164.548 1.00 35.77  ? 349  HIS C CE1   1 
ATOM   12155 N  NE2   . HIS C 2 334  ? 113.640 135.928 165.358 1.00 35.77  ? 349  HIS C NE2   1 
ATOM   12156 N  N     . PRO C 2 335  ? 112.611 132.907 162.175 1.00 35.29  ? 350  PRO C N     1 
ATOM   12157 C  CA    . PRO C 2 335  ? 112.757 133.200 160.740 1.00 35.29  ? 350  PRO C CA    1 
ATOM   12158 C  C     . PRO C 2 335  ? 114.188 133.466 160.314 1.00 35.29  ? 350  PRO C C     1 
ATOM   12159 O  O     . PRO C 2 335  ? 114.549 133.158 159.172 1.00 35.29  ? 350  PRO C O     1 
ATOM   12160 C  CB    . PRO C 2 335  ? 111.873 134.438 160.549 1.00 35.29  ? 350  PRO C CB    1 
ATOM   12161 C  CG    . PRO C 2 335  ? 110.850 134.325 161.619 1.00 35.29  ? 350  PRO C CG    1 
ATOM   12162 C  CD    . PRO C 2 335  ? 111.562 133.730 162.799 1.00 35.29  ? 350  PRO C CD    1 
ATOM   12163 N  N     . CYS C 2 336  ? 115.015 134.034 161.190 1.00 33.32  ? 351  CYS C N     1 
ATOM   12164 C  CA    . CYS C 2 336  ? 116.415 134.261 160.861 1.00 33.32  ? 351  CYS C CA    1 
ATOM   12165 C  C     . CYS C 2 336  ? 117.271 133.014 161.028 1.00 33.32  ? 351  CYS C C     1 
ATOM   12166 O  O     . CYS C 2 336  ? 118.460 133.051 160.697 1.00 33.32  ? 351  CYS C O     1 
ATOM   12167 C  CB    . CYS C 2 336  ? 116.983 135.391 161.723 1.00 33.32  ? 351  CYS C CB    1 
ATOM   12168 S  SG    . CYS C 2 336  ? 116.222 137.002 161.431 1.00 33.32  ? 351  CYS C SG    1 
ATOM   12169 N  N     . LEU C 2 337  ? 116.701 131.922 161.536 1.00 32.21  ? 352  LEU C N     1 
ATOM   12170 C  CA    . LEU C 2 337  ? 117.418 130.667 161.720 1.00 32.21  ? 352  LEU C CA    1 
ATOM   12171 C  C     . LEU C 2 337  ? 116.914 129.537 160.842 1.00 32.21  ? 352  LEU C C     1 
ATOM   12172 O  O     . LEU C 2 337  ? 117.697 128.651 160.499 1.00 32.21  ? 352  LEU C O     1 
ATOM   12173 C  CB    . LEU C 2 337  ? 117.336 130.210 163.181 1.00 32.21  ? 352  LEU C CB    1 
ATOM   12174 C  CG    . LEU C 2 337  ? 118.132 130.993 164.220 1.00 32.21  ? 352  LEU C CG    1 
ATOM   12175 C  CD1   . LEU C 2 337  ? 118.063 130.280 165.553 1.00 32.21  ? 352  LEU C CD1   1 
ATOM   12176 C  CD2   . LEU C 2 337  ? 119.567 131.155 163.768 1.00 32.21  ? 352  LEU C CD2   1 
ATOM   12177 N  N     . ALA C 2 338  ? 115.632 129.542 160.486 1.00 32.06  ? 353  ALA C N     1 
ATOM   12178 C  CA    . ALA C 2 338  ? 115.052 128.413 159.776 1.00 32.06  ? 353  ALA C CA    1 
ATOM   12179 C  C     . ALA C 2 338  ? 115.813 128.159 158.478 1.00 32.06  ? 353  ALA C C     1 
ATOM   12180 O  O     . ALA C 2 338  ? 116.217 129.109 157.797 1.00 32.06  ? 353  ALA C O     1 
ATOM   12181 C  CB    . ALA C 2 338  ? 113.573 128.666 159.479 1.00 32.06  ? 353  ALA C CB    1 
ATOM   12182 N  N     . PRO C 2 339  ? 116.044 126.895 158.116 1.00 34.73  ? 354  PRO C N     1 
ATOM   12183 C  CA    . PRO C 2 339  ? 116.838 126.626 156.908 1.00 34.73  ? 354  PRO C CA    1 
ATOM   12184 C  C     . PRO C 2 339  ? 116.119 126.981 155.620 1.00 34.73  ? 354  PRO C C     1 
ATOM   12185 O  O     . PRO C 2 339  ? 116.750 127.489 154.685 1.00 34.73  ? 354  PRO C O     1 
ATOM   12186 C  CB    . PRO C 2 339  ? 117.118 125.121 157.012 1.00 34.73  ? 354  PRO C CB    1 
ATOM   12187 C  CG    . PRO C 2 339  ? 115.978 124.587 157.808 1.00 34.73  ? 354  PRO C CG    1 
ATOM   12188 C  CD    . PRO C 2 339  ? 115.631 125.657 158.800 1.00 34.73  ? 354  PRO C CD    1 
ATOM   12189 N  N     . ILE C 2 340  ? 114.814 126.730 155.546 1.00 37.53  ? 355  ILE C N     1 
ATOM   12190 C  CA    . ILE C 2 340  ? 114.032 126.895 154.326 1.00 37.53  ? 355  ILE C CA    1 
ATOM   12191 C  C     . ILE C 2 340  ? 112.945 127.928 154.579 1.00 37.53  ? 355  ILE C C     1 
ATOM   12192 O  O     . ILE C 2 340  ? 112.146 127.779 155.511 1.00 37.53  ? 355  ILE C O     1 
ATOM   12193 C  CB    . ILE C 2 340  ? 113.414 125.562 153.872 1.00 37.53  ? 355  ILE C CB    1 
ATOM   12194 C  CG1   . ILE C 2 340  ? 114.499 124.629 153.334 1.00 37.53  ? 355  ILE C CG1   1 
ATOM   12195 C  CG2   . ILE C 2 340  ? 112.331 125.806 152.840 1.00 37.53  ? 355  ILE C CG2   1 
ATOM   12196 C  CD1   . ILE C 2 340  ? 114.002 123.239 153.027 1.00 37.53  ? 355  ILE C CD1   1 
ATOM   12197 N  N     . LYS C 2 341  ? 112.906 128.963 153.740 1.00 36.80  ? 356  LYS C N     1 
ATOM   12198 C  CA    . LYS C 2 341  ? 111.938 130.044 153.883 1.00 36.80  ? 356  LYS C CA    1 
ATOM   12199 C  C     . LYS C 2 341  ? 110.647 129.784 153.111 1.00 36.80  ? 356  LYS C C     1 
ATOM   12200 O  O     . LYS C 2 341  ? 109.552 129.985 153.646 1.00 36.80  ? 356  LYS C O     1 
ATOM   12201 C  CB    . LYS C 2 341  ? 112.555 131.368 153.423 1.00 36.80  ? 356  LYS C CB    1 
ATOM   12202 C  CG    . LYS C 2 341  ? 113.246 132.165 154.517 1.00 36.80  ? 356  LYS C CG    1 
ATOM   12203 C  CD    . LYS C 2 341  ? 114.640 131.649 154.823 1.00 36.80  ? 356  LYS C CD    1 
ATOM   12204 C  CE    . LYS C 2 341  ? 115.324 132.541 155.845 1.00 36.80  ? 356  LYS C CE    1 
ATOM   12205 N  NZ    . LYS C 2 341  ? 116.748 132.178 156.062 1.00 36.80  ? 356  LYS C NZ    1 
ATOM   12206 N  N     . VAL C 2 342  ? 110.751 129.343 151.858 1.00 42.20  ? 357  VAL C N     1 
ATOM   12207 C  CA    . VAL C 2 342  ? 109.605 129.227 150.965 1.00 42.20  ? 357  VAL C CA    1 
ATOM   12208 C  C     . VAL C 2 342  ? 109.562 127.820 150.387 1.00 42.20  ? 357  VAL C C     1 
ATOM   12209 O  O     . VAL C 2 342  ? 110.599 127.258 150.019 1.00 42.20  ? 357  VAL C O     1 
ATOM   12210 C  CB    . VAL C 2 342  ? 109.664 130.271 149.830 1.00 42.20  ? 357  VAL C CB    1 
ATOM   12211 C  CG1   . VAL C 2 342  ? 108.361 130.288 149.055 1.00 42.20  ? 357  VAL C CG1   1 
ATOM   12212 C  CG2   . VAL C 2 342  ? 109.977 131.650 150.387 1.00 42.20  ? 357  VAL C CG2   1 
ATOM   12213 N  N     . ALA C 2 343  ? 108.361 127.253 150.303 1.00 47.39  ? 358  ALA C N     1 
ATOM   12214 C  CA    . ALA C 2 343  ? 108.141 125.922 149.741 1.00 47.39  ? 358  ALA C CA    1 
ATOM   12215 C  C     . ALA C 2 343  ? 107.129 126.040 148.604 1.00 47.39  ? 358  ALA C C     1 
ATOM   12216 O  O     . ALA C 2 343  ? 105.917 126.010 148.831 1.00 47.39  ? 358  ALA C O     1 
ATOM   12217 C  CB    . ALA C 2 343  ? 107.668 124.943 150.812 1.00 47.39  ? 358  ALA C CB    1 
ATOM   12218 N  N     . LEU C 2 344  ? 107.631 126.174 147.379 1.00 55.23  ? 359  LEU C N     1 
ATOM   12219 C  CA    . LEU C 2 344  ? 106.768 126.258 146.212 1.00 55.23  ? 359  LEU C CA    1 
ATOM   12220 C  C     . LEU C 2 344  ? 106.105 124.912 145.936 1.00 55.23  ? 359  LEU C C     1 
ATOM   12221 O  O     . LEU C 2 344  ? 106.559 123.860 146.392 1.00 55.23  ? 359  LEU C O     1 
ATOM   12222 C  CB    . LEU C 2 344  ? 107.563 126.700 144.986 1.00 55.23  ? 359  LEU C CB    1 
ATOM   12223 C  CG    . LEU C 2 344  ? 108.418 127.952 145.161 1.00 55.23  ? 359  LEU C CG    1 
ATOM   12224 C  CD1   . LEU C 2 344  ? 109.115 128.300 143.864 1.00 55.23  ? 359  LEU C CD1   1 
ATOM   12225 C  CD2   . LEU C 2 344  ? 107.567 129.111 145.636 1.00 55.23  ? 359  LEU C CD2   1 
ATOM   12226 N  N     . ASP C 2 345  ? 105.071 124.977 145.104 1.00 64.02  ? 360  ASP C N     1 
ATOM   12227 C  CA    . ASP C 2 345  ? 104.360 123.769 144.723 1.00 64.02  ? 360  ASP C CA    1 
ATOM   12228 C  C     . ASP C 2 345  ? 103.394 124.062 143.587 1.00 64.02  ? 360  ASP C C     1 
ATOM   12229 O  O     . ASP C 2 345  ? 103.372 125.173 143.060 1.00 64.02  ? 360  ASP C O     1 
ATOM   12230 C  CB    . ASP C 2 345  ? 103.602 123.191 145.917 1.00 64.02  ? 360  ASP C CB    1 
ATOM   12231 C  CG    . ASP C 2 345  ? 104.256 121.947 146.472 1.00 64.02  ? 360  ASP C CG    1 
ATOM   12232 O  OD1   . ASP C 2 345  ? 104.886 121.208 145.690 1.00 64.02  ? 360  ASP C OD1   1 
ATOM   12233 O  OD2   . ASP C 2 345  ? 104.130 121.701 147.689 1.00 64.02  ? 360  ASP C OD2   1 
ATOM   12234 N  N     . VAL C 2 346  ? 102.604 123.075 143.197 1.00 67.44  ? 361  VAL C N     1 
ATOM   12235 C  CA    . VAL C 2 346  ? 101.614 123.219 142.140 1.00 67.44  ? 361  VAL C CA    1 
ATOM   12236 C  C     . VAL C 2 346  ? 100.337 122.519 142.584 1.00 67.44  ? 361  VAL C C     1 
ATOM   12237 O  O     . VAL C 2 346  ? 100.339 121.684 143.490 1.00 67.44  ? 361  VAL C O     1 
ATOM   12238 C  CB    . VAL C 2 346  ? 102.096 122.644 140.791 1.00 67.44  ? 361  VAL C CB    1 
ATOM   12239 C  CG1   . VAL C 2 346  ? 103.374 123.331 140.340 1.00 67.44  ? 361  VAL C CG1   1 
ATOM   12240 C  CG2   . VAL C 2 346  ? 102.299 121.141 140.898 1.00 67.44  ? 361  VAL C CG2   1 
ATOM   12241 N  N     . GLY C 2 347  ? 99.236  122.874 141.931 1.00 63.67  ? 362  GLY C N     1 
ATOM   12242 C  CA    . GLY C 2 347  ? 97.954  122.281 142.271 1.00 63.67  ? 362  GLY C CA    1 
ATOM   12243 C  C     . GLY C 2 347  ? 96.924  122.588 141.209 1.00 63.67  ? 362  GLY C C     1 
ATOM   12244 O  O     . GLY C 2 347  ? 97.144  123.412 140.316 1.00 63.67  ? 362  GLY C O     1 
ATOM   12245 N  N     . LYS C 2 348  ? 95.788  121.903 141.326 1.00 68.48  ? 363  LYS C N     1 
ATOM   12246 C  CA    . LYS C 2 348  ? 94.662  122.066 140.408 1.00 68.48  ? 363  LYS C CA    1 
ATOM   12247 C  C     . LYS C 2 348  ? 95.073  121.836 138.956 1.00 68.48  ? 363  LYS C C     1 
ATOM   12248 O  O     . LYS C 2 348  ? 94.729  120.818 138.358 1.00 68.48  ? 363  LYS C O     1 
ATOM   12249 C  CB    . LYS C 2 348  ? 94.040  123.456 140.566 1.00 68.48  ? 363  LYS C CB    1 
ATOM   12250 C  CG    . LYS C 2 348  ? 93.372  123.687 141.911 1.00 68.48  ? 363  LYS C CG    1 
ATOM   12251 C  CD    . LYS C 2 348  ? 93.098  125.164 142.145 1.00 68.48  ? 363  LYS C CD    1 
ATOM   12252 C  CE    . LYS C 2 348  ? 92.306  125.774 141.001 1.00 68.48  ? 363  LYS C CE    1 
ATOM   12253 N  NZ    . LYS C 2 348  ? 92.116  127.240 141.182 1.00 68.48  ? 363  LYS C NZ    1 
ATOM   12254 N  N     . THR C 2 351  ? 99.805  122.583 133.255 1.00 76.79  ? 366  THR C N     1 
ATOM   12255 C  CA    . THR C 2 351  ? 100.852 121.824 133.929 1.00 76.79  ? 366  THR C CA    1 
ATOM   12256 C  C     . THR C 2 351  ? 102.229 122.387 133.608 1.00 76.79  ? 366  THR C C     1 
ATOM   12257 O  O     . THR C 2 351  ? 102.934 122.871 134.493 1.00 76.79  ? 366  THR C O     1 
ATOM   12258 C  CB    . THR C 2 351  ? 100.816 120.338 133.536 1.00 76.79  ? 366  THR C CB    1 
ATOM   12259 O  OG1   . THR C 2 351  ? 99.566  119.765 133.939 1.00 76.79  ? 366  THR C OG1   1 
ATOM   12260 C  CG2   . THR C 2 351  ? 101.956 119.585 134.204 1.00 76.79  ? 366  THR C CG2   1 
ATOM   12261 N  N     . VAL C 2 352  ? 102.610 122.311 132.331 1.00 78.33  ? 367  VAL C N     1 
ATOM   12262 C  CA    . VAL C 2 352  ? 103.896 122.853 131.904 1.00 78.33  ? 367  VAL C CA    1 
ATOM   12263 C  C     . VAL C 2 352  ? 103.924 124.364 132.096 1.00 78.33  ? 367  VAL C C     1 
ATOM   12264 O  O     . VAL C 2 352  ? 104.958 124.942 132.451 1.00 78.33  ? 367  VAL C O     1 
ATOM   12265 C  CB    . VAL C 2 352  ? 104.184 122.459 130.444 1.00 78.33  ? 367  VAL C CB    1 
ATOM   12266 C  CG1   . VAL C 2 352  ? 105.595 122.865 130.051 1.00 78.33  ? 367  VAL C CG1   1 
ATOM   12267 C  CG2   . VAL C 2 352  ? 103.978 120.965 130.250 1.00 78.33  ? 367  VAL C CG2   1 
ATOM   12268 N  N     . GLU C 2 353  ? 102.791 125.028 131.852 1.00 78.52  ? 368  GLU C N     1 
ATOM   12269 C  CA    . GLU C 2 353  ? 102.703 126.461 132.117 1.00 78.52  ? 368  GLU C CA    1 
ATOM   12270 C  C     . GLU C 2 353  ? 102.912 126.753 133.596 1.00 78.52  ? 368  GLU C C     1 
ATOM   12271 O  O     . GLU C 2 353  ? 103.642 127.684 133.960 1.00 78.52  ? 368  GLU C O     1 
ATOM   12272 C  CB    . GLU C 2 353  ? 101.349 127.001 131.651 1.00 78.52  ? 368  GLU C CB    1 
ATOM   12273 C  CG    . GLU C 2 353  ? 100.961 126.620 130.227 1.00 78.52  ? 368  GLU C CG    1 
ATOM   12274 C  CD    . GLU C 2 353  ? 100.338 125.238 130.132 1.00 78.52  ? 368  GLU C CD    1 
ATOM   12275 O  OE1   . GLU C 2 353  ? 100.161 124.589 131.185 1.00 78.52  ? 368  GLU C OE1   1 
ATOM   12276 O  OE2   . GLU C 2 353  ? 100.027 124.801 129.004 1.00 78.52  ? 368  GLU C OE2   1 
ATOM   12277 N  N     . LEU C 2 354  ? 102.279 125.960 134.464 1.00 71.16  ? 369  LEU C N     1 
ATOM   12278 C  CA    . LEU C 2 354  ? 102.514 126.094 135.897 1.00 71.16  ? 369  LEU C CA    1 
ATOM   12279 C  C     . LEU C 2 354  ? 103.968 125.803 136.235 1.00 71.16  ? 369  LEU C C     1 
ATOM   12280 O  O     . LEU C 2 354  ? 104.548 126.443 137.120 1.00 71.16  ? 369  LEU C O     1 
ATOM   12281 C  CB    . LEU C 2 354  ? 101.587 125.159 136.670 1.00 71.16  ? 369  LEU C CB    1 
ATOM   12282 C  CG    . LEU C 2 354  ? 100.098 125.280 136.349 1.00 71.16  ? 369  LEU C CG    1 
ATOM   12283 C  CD1   . LEU C 2 354  ? 99.278  124.358 137.238 1.00 71.16  ? 369  LEU C CD1   1 
ATOM   12284 C  CD2   . LEU C 2 354  ? 99.640  126.721 136.492 1.00 71.16  ? 369  LEU C CD2   1 
ATOM   12285 N  N     . ARG C 2 355  ? 104.570 124.834 135.542 1.00 72.16  ? 370  ARG C N     1 
ATOM   12286 C  CA    . ARG C 2 355  ? 105.982 124.540 135.754 1.00 72.16  ? 370  ARG C CA    1 
ATOM   12287 C  C     . ARG C 2 355  ? 106.846 125.753 135.448 1.00 72.16  ? 370  ARG C C     1 
ATOM   12288 O  O     . ARG C 2 355  ? 107.755 126.086 136.215 1.00 72.16  ? 370  ARG C O     1 
ATOM   12289 C  CB    . ARG C 2 355  ? 106.409 123.353 134.892 1.00 72.16  ? 370  ARG C CB    1 
ATOM   12290 C  CG    . ARG C 2 355  ? 105.941 122.006 135.404 1.00 72.16  ? 370  ARG C CG    1 
ATOM   12291 C  CD    . ARG C 2 355  ? 106.577 121.687 136.742 1.00 72.16  ? 370  ARG C CD    1 
ATOM   12292 N  NE    . ARG C 2 355  ? 106.245 120.342 137.196 1.00 72.16  ? 370  ARG C NE    1 
ATOM   12293 C  CZ    . ARG C 2 355  ? 105.135 120.027 137.848 1.00 72.16  ? 370  ARG C CZ    1 
ATOM   12294 N  NH1   . ARG C 2 355  ? 104.218 120.937 138.130 1.00 72.16  ? 370  ARG C NH1   1 
ATOM   12295 N  NH2   . ARG C 2 355  ? 104.940 118.766 138.224 1.00 72.16  ? 370  ARG C NH2   1 
ATOM   12296 N  N     . GLN C 2 356  ? 106.573 126.434 134.333 1.00 70.32  ? 371  GLN C N     1 
ATOM   12297 C  CA    . GLN C 2 356  ? 107.363 127.609 133.979 1.00 70.32  ? 371  GLN C CA    1 
ATOM   12298 C  C     . GLN C 2 356  ? 107.118 128.755 134.952 1.00 70.32  ? 371  GLN C C     1 
ATOM   12299 O  O     . GLN C 2 356  ? 108.048 129.499 135.290 1.00 70.32  ? 371  GLN C O     1 
ATOM   12300 C  CB    . GLN C 2 356  ? 107.054 128.044 132.548 1.00 70.32  ? 371  GLN C CB    1 
ATOM   12301 C  CG    . GLN C 2 356  ? 107.927 129.186 132.062 1.00 70.32  ? 371  GLN C CG    1 
ATOM   12302 C  CD    . GLN C 2 356  ? 109.406 128.879 132.194 1.00 70.32  ? 371  GLN C CD    1 
ATOM   12303 O  OE1   . GLN C 2 356  ? 109.847 127.763 131.921 1.00 70.32  ? 371  GLN C OE1   1 
ATOM   12304 N  NE2   . GLN C 2 356  ? 110.181 129.869 132.623 1.00 70.32  ? 371  GLN C NE2   1 
ATOM   12305 N  N     . VAL C 2 357  ? 105.874 128.919 135.407 1.00 66.00  ? 372  VAL C N     1 
ATOM   12306 C  CA    . VAL C 2 357  ? 105.577 129.959 136.390 1.00 66.00  ? 372  VAL C CA    1 
ATOM   12307 C  C     . VAL C 2 357  ? 106.365 129.714 137.670 1.00 66.00  ? 372  VAL C C     1 
ATOM   12308 O  O     . VAL C 2 357  ? 106.996 130.627 138.221 1.00 66.00  ? 372  VAL C O     1 
ATOM   12309 C  CB    . VAL C 2 357  ? 104.064 130.023 136.664 1.00 66.00  ? 372  VAL C CB    1 
ATOM   12310 C  CG1   . VAL C 2 357  ? 103.782 130.902 137.871 1.00 66.00  ? 372  VAL C CG1   1 
ATOM   12311 C  CG2   . VAL C 2 357  ? 103.327 130.546 135.444 1.00 66.00  ? 372  VAL C CG2   1 
ATOM   12312 N  N     . CYS C 2 358  ? 106.345 128.470 138.155 1.00 64.71  ? 373  CYS C N     1 
ATOM   12313 C  CA    . CYS C 2 358  ? 107.101 128.126 139.353 1.00 64.71  ? 373  CYS C CA    1 
ATOM   12314 C  C     . CYS C 2 358  ? 108.593 128.305 139.128 1.00 64.71  ? 373  CYS C C     1 
ATOM   12315 O  O     . CYS C 2 358  ? 109.312 128.744 140.029 1.00 64.71  ? 373  CYS C O     1 
ATOM   12316 C  CB    . CYS C 2 358  ? 106.797 126.690 139.778 1.00 64.71  ? 373  CYS C CB    1 
ATOM   12317 S  SG    . CYS C 2 358  ? 105.107 126.419 140.343 1.00 64.71  ? 373  CYS C SG    1 
ATOM   12318 N  N     . GLN C 2 359  ? 109.077 127.962 137.934 1.00 60.12  ? 374  GLN C N     1 
ATOM   12319 C  CA    . GLN C 2 359  ? 110.494 128.116 137.631 1.00 60.12  ? 374  GLN C CA    1 
ATOM   12320 C  C     . GLN C 2 359  ? 110.909 129.579 137.700 1.00 60.12  ? 374  GLN C C     1 
ATOM   12321 O  O     . GLN C 2 359  ? 111.937 129.919 138.296 1.00 60.12  ? 374  GLN C O     1 
ATOM   12322 C  CB    . GLN C 2 359  ? 110.791 127.533 136.249 1.00 60.12  ? 374  GLN C CB    1 
ATOM   12323 C  CG    . GLN C 2 359  ? 112.243 127.164 136.024 1.00 60.12  ? 374  GLN C CG    1 
ATOM   12324 C  CD    . GLN C 2 359  ? 112.620 125.865 136.704 1.00 60.12  ? 374  GLN C CD    1 
ATOM   12325 O  OE1   . GLN C 2 359  ? 111.754 125.099 137.126 1.00 60.12  ? 374  GLN C OE1   1 
ATOM   12326 N  NE2   . GLN C 2 359  ? 113.918 125.610 136.814 1.00 60.12  ? 374  GLN C NE2   1 
ATOM   12327 N  N     . GLY C 2 360  ? 110.110 130.462 137.101 1.00 56.28  ? 375  GLY C N     1 
ATOM   12328 C  CA    . GLY C 2 360  ? 110.426 131.880 137.150 1.00 56.28  ? 375  GLY C CA    1 
ATOM   12329 C  C     . GLY C 2 360  ? 110.361 132.442 138.556 1.00 56.28  ? 375  GLY C C     1 
ATOM   12330 O  O     . GLY C 2 360  ? 111.233 133.215 138.969 1.00 56.28  ? 375  GLY C O     1 
ATOM   12331 N  N     . LEU C 2 361  ? 109.330 132.058 139.314 1.00 53.22  ? 376  LEU C N     1 
ATOM   12332 C  CA    . LEU C 2 361  ? 109.216 132.515 140.695 1.00 53.22  ? 376  LEU C CA    1 
ATOM   12333 C  C     . LEU C 2 361  ? 110.402 132.045 141.529 1.00 53.22  ? 376  LEU C C     1 
ATOM   12334 O  O     . LEU C 2 361  ? 110.985 132.825 142.293 1.00 53.22  ? 376  LEU C O     1 
ATOM   12335 C  CB    . LEU C 2 361  ? 107.901 132.017 141.294 1.00 53.22  ? 376  LEU C CB    1 
ATOM   12336 C  CG    . LEU C 2 361  ? 107.621 132.313 142.766 1.00 53.22  ? 376  LEU C CG    1 
ATOM   12337 C  CD1   . LEU C 2 361  ? 107.656 133.808 143.023 1.00 53.22  ? 376  LEU C CD1   1 
ATOM   12338 C  CD2   . LEU C 2 361  ? 106.279 131.726 143.172 1.00 53.22  ? 376  LEU C CD2   1 
ATOM   12339 N  N     . LEU C 2 362  ? 110.777 130.772 141.384 1.00 52.94  ? 377  LEU C N     1 
ATOM   12340 C  CA    . LEU C 2 362  ? 111.915 130.227 142.112 1.00 52.94  ? 377  LEU C CA    1 
ATOM   12341 C  C     . LEU C 2 362  ? 113.202 130.940 141.735 1.00 52.94  ? 377  LEU C C     1 
ATOM   12342 O  O     . LEU C 2 362  ? 114.025 131.247 142.604 1.00 52.94  ? 377  LEU C O     1 
ATOM   12343 C  CB    . LEU C 2 362  ? 112.035 128.729 141.833 1.00 52.94  ? 377  LEU C CB    1 
ATOM   12344 C  CG    . LEU C 2 362  ? 113.326 128.035 142.262 1.00 52.94  ? 377  LEU C CG    1 
ATOM   12345 C  CD1   . LEU C 2 362  ? 113.490 128.113 143.763 1.00 52.94  ? 377  LEU C CD1   1 
ATOM   12346 C  CD2   . LEU C 2 362  ? 113.334 126.590 141.798 1.00 52.94  ? 377  LEU C CD2   1 
ATOM   12347 N  N     . ASN C 2 363  ? 113.401 131.202 140.443 1.00 54.14  ? 378  ASN C N     1 
ATOM   12348 C  CA    . ASN C 2 363  ? 114.616 131.883 140.015 1.00 54.14  ? 378  ASN C CA    1 
ATOM   12349 C  C     . ASN C 2 363  ? 114.685 133.290 140.589 1.00 54.14  ? 378  ASN C C     1 
ATOM   12350 O  O     . ASN C 2 363  ? 115.747 133.729 141.045 1.00 54.14  ? 378  ASN C O     1 
ATOM   12351 C  CB    . ASN C 2 363  ? 114.691 131.915 138.490 1.00 54.14  ? 378  ASN C CB    1 
ATOM   12352 C  CG    . ASN C 2 363  ? 116.109 131.798 137.979 1.00 54.14  ? 378  ASN C CG    1 
ATOM   12353 O  OD1   . ASN C 2 363  ? 116.840 132.785 137.908 1.00 54.14  ? 378  ASN C OD1   1 
ATOM   12354 N  ND2   . ASN C 2 363  ? 116.509 130.583 137.622 1.00 54.14  ? 378  ASN C ND2   1 
ATOM   12355 N  N     . GLU C 2 364  ? 113.560 134.010 140.590 1.00 57.62  ? 379  GLU C N     1 
ATOM   12356 C  CA    . GLU C 2 364  ? 113.549 135.352 141.167 1.00 57.62  ? 379  GLU C CA    1 
ATOM   12357 C  C     . GLU C 2 364  ? 113.857 135.308 142.659 1.00 57.62  ? 379  GLU C C     1 
ATOM   12358 O  O     . GLU C 2 364  ? 114.672 136.094 143.164 1.00 57.62  ? 379  GLU C O     1 
ATOM   12359 C  CB    . GLU C 2 364  ? 112.199 136.022 140.916 1.00 57.62  ? 379  GLU C CB    1 
ATOM   12360 C  CG    . GLU C 2 364  ? 112.094 137.425 141.492 1.00 57.62  ? 379  GLU C CG    1 
ATOM   12361 C  CD    . GLU C 2 364  ? 110.755 138.075 141.204 1.00 57.62  ? 379  GLU C CD    1 
ATOM   12362 O  OE1   . GLU C 2 364  ? 109.928 137.450 140.510 1.00 57.62  ? 379  GLU C OE1   1 
ATOM   12363 O  OE2   . GLU C 2 364  ? 110.531 139.211 141.673 1.00 57.62  ? 379  GLU C OE2   1 
ATOM   12364 N  N     . LEU C 2 365  ? 113.223 134.378 143.381 1.00 53.32  ? 380  LEU C N     1 
ATOM   12365 C  CA    . LEU C 2 365  ? 113.458 134.271 144.818 1.00 53.32  ? 380  LEU C CA    1 
ATOM   12366 C  C     . LEU C 2 365  ? 114.913 133.936 145.118 1.00 53.32  ? 380  LEU C C     1 
ATOM   12367 O  O     . LEU C 2 365  ? 115.515 134.513 146.030 1.00 53.32  ? 380  LEU C O     1 
ATOM   12368 C  CB    . LEU C 2 365  ? 112.528 133.223 145.426 1.00 53.32  ? 380  LEU C CB    1 
ATOM   12369 C  CG    . LEU C 2 365  ? 111.046 133.591 145.484 1.00 53.32  ? 380  LEU C CG    1 
ATOM   12370 C  CD1   . LEU C 2 365  ? 110.233 132.473 146.117 1.00 53.32  ? 380  LEU C CD1   1 
ATOM   12371 C  CD2   . LEU C 2 365  ? 110.860 134.890 146.246 1.00 53.32  ? 380  LEU C CD2   1 
ATOM   12372 N  N     . LEU C 2 366  ? 115.496 133.002 144.361 1.00 47.28  ? 381  LEU C N     1 
ATOM   12373 C  CA    . LEU C 2 366  ? 116.894 132.641 144.575 1.00 47.28  ? 381  LEU C CA    1 
ATOM   12374 C  C     . LEU C 2 366  ? 117.824 133.801 144.250 1.00 47.28  ? 381  LEU C C     1 
ATOM   12375 O  O     . LEU C 2 366  ? 118.814 134.022 144.956 1.00 47.28  ? 381  LEU C O     1 
ATOM   12376 C  CB    . LEU C 2 366  ? 117.257 131.415 143.738 1.00 47.28  ? 381  LEU C CB    1 
ATOM   12377 C  CG    . LEU C 2 366  ? 116.564 130.110 144.123 1.00 47.28  ? 381  LEU C CG    1 
ATOM   12378 C  CD1   . LEU C 2 366  ? 117.082 128.963 143.275 1.00 47.28  ? 381  LEU C CD1   1 
ATOM   12379 C  CD2   . LEU C 2 366  ? 116.747 129.822 145.602 1.00 47.28  ? 381  LEU C CD2   1 
ATOM   12380 N  N     . GLU C 2 367  ? 117.532 134.547 143.181 1.00 51.87  ? 382  GLU C N     1 
ATOM   12381 C  CA    . GLU C 2 367  ? 118.363 135.697 142.845 1.00 51.87  ? 382  GLU C CA    1 
ATOM   12382 C  C     . GLU C 2 367  ? 118.316 136.745 143.947 1.00 51.87  ? 382  GLU C C     1 
ATOM   12383 O  O     . GLU C 2 367  ? 119.333 137.376 144.257 1.00 51.87  ? 382  GLU C O     1 
ATOM   12384 C  CB    . GLU C 2 367  ? 117.922 136.300 141.513 1.00 51.87  ? 382  GLU C CB    1 
ATOM   12385 C  CG    . GLU C 2 367  ? 118.294 135.466 140.302 1.00 51.87  ? 382  GLU C CG    1 
ATOM   12386 C  CD    . GLU C 2 367  ? 117.871 136.112 138.999 1.00 51.87  ? 382  GLU C CD    1 
ATOM   12387 O  OE1   . GLU C 2 367  ? 117.509 137.307 139.017 1.00 51.87  ? 382  GLU C OE1   1 
ATOM   12388 O  OE2   . GLU C 2 367  ? 117.898 135.424 137.957 1.00 51.87  ? 382  GLU C OE2   1 
ATOM   12389 N  N     . ASN C 2 368  ? 117.143 136.946 144.548 1.00 54.38  ? 383  ASN C N     1 
ATOM   12390 C  CA    . ASN C 2 368  ? 117.044 137.914 145.636 1.00 54.38  ? 383  ASN C CA    1 
ATOM   12391 C  C     . ASN C 2 368  ? 117.861 137.480 146.847 1.00 54.38  ? 383  ASN C C     1 
ATOM   12392 O  O     . ASN C 2 368  ? 118.528 138.307 147.479 1.00 54.38  ? 383  ASN C O     1 
ATOM   12393 C  CB    . ASN C 2 368  ? 115.581 138.130 146.010 1.00 54.38  ? 383  ASN C CB    1 
ATOM   12394 C  CG    . ASN C 2 368  ? 114.834 138.920 144.961 1.00 54.38  ? 383  ASN C CG    1 
ATOM   12395 O  OD1   . ASN C 2 368  ? 114.829 140.150 144.983 1.00 54.38  ? 383  ASN C OD1   1 
ATOM   12396 N  ND2   . ASN C 2 368  ? 114.202 138.218 144.029 1.00 54.38  ? 383  ASN C ND2   1 
ATOM   12397 N  N     . GLY C 2 369  ? 117.829 136.193 147.184 1.00 51.31  ? 384  GLY C N     1 
ATOM   12398 C  CA    . GLY C 2 369  ? 118.596 135.698 148.312 1.00 51.31  ? 384  GLY C CA    1 
ATOM   12399 C  C     . GLY C 2 369  ? 117.781 134.890 149.299 1.00 51.31  ? 384  GLY C C     1 
ATOM   12400 O  O     . GLY C 2 369  ? 118.225 134.632 150.421 1.00 51.31  ? 384  GLY C O     1 
ATOM   12401 N  N     . ILE C 2 370  ? 116.585 134.482 148.891 1.00 48.77  ? 385  ILE C N     1 
ATOM   12402 C  CA    . ILE C 2 370  ? 115.681 133.711 149.735 1.00 48.77  ? 385  ILE C CA    1 
ATOM   12403 C  C     . ILE C 2 370  ? 115.874 132.237 149.415 1.00 48.77  ? 385  ILE C C     1 
ATOM   12404 O  O     . ILE C 2 370  ? 115.727 131.819 148.260 1.00 48.77  ? 385  ILE C O     1 
ATOM   12405 C  CB    . ILE C 2 370  ? 114.221 134.137 149.520 1.00 48.77  ? 385  ILE C CB    1 
ATOM   12406 C  CG1   . ILE C 2 370  ? 114.052 135.621 149.844 1.00 48.77  ? 385  ILE C CG1   1 
ATOM   12407 C  CG2   . ILE C 2 370  ? 113.286 133.293 150.367 1.00 48.77  ? 385  ILE C CG2   1 
ATOM   12408 C  CD1   . ILE C 2 370  ? 112.698 136.169 149.476 1.00 48.77  ? 385  ILE C CD1   1 
ATOM   12409 N  N     . SER C 2 371  ? 116.215 131.448 150.430 1.00 42.39  ? 386  SER C N     1 
ATOM   12410 C  CA    . SER C 2 371  ? 116.337 130.009 150.242 1.00 42.39  ? 386  SER C CA    1 
ATOM   12411 C  C     . SER C 2 371  ? 114.954 129.398 150.063 1.00 42.39  ? 386  SER C C     1 
ATOM   12412 O  O     . SER C 2 371  ? 114.042 129.660 150.851 1.00 42.39  ? 386  SER C O     1 
ATOM   12413 C  CB    . SER C 2 371  ? 117.053 129.377 151.431 1.00 42.39  ? 386  SER C CB    1 
ATOM   12414 O  OG    . SER C 2 371  ? 116.364 129.648 152.637 1.00 42.39  ? 386  SER C OG    1 
ATOM   12415 N  N     . VAL C 2 372  ? 114.798 128.586 149.023 1.00 44.25  ? 387  VAL C N     1 
ATOM   12416 C  CA    . VAL C 2 372  ? 113.502 128.050 148.631 1.00 44.25  ? 387  VAL C CA    1 
ATOM   12417 C  C     . VAL C 2 372  ? 113.595 126.535 148.535 1.00 44.25  ? 387  VAL C C     1 
ATOM   12418 O  O     . VAL C 2 372  ? 114.605 125.992 148.073 1.00 44.25  ? 387  VAL C O     1 
ATOM   12419 C  CB    . VAL C 2 372  ? 113.024 128.644 147.289 1.00 44.25  ? 387  VAL C CB    1 
ATOM   12420 C  CG1   . VAL C 2 372  ? 111.602 128.206 146.983 1.00 44.25  ? 387  VAL C CG1   1 
ATOM   12421 C  CG2   . VAL C 2 372  ? 113.126 130.158 147.306 1.00 44.25  ? 387  VAL C CG2   1 
ATOM   12422 N  N     . TRP C 2 373  ? 112.540 125.855 148.975 1.00 49.56  ? 388  TRP C N     1 
ATOM   12423 C  CA    . TRP C 2 373  ? 112.418 124.419 148.797 1.00 49.56  ? 388  TRP C CA    1 
ATOM   12424 C  C     . TRP C 2 373  ? 111.596 124.161 147.545 1.00 49.56  ? 388  TRP C C     1 
ATOM   12425 O  O     . TRP C 2 373  ? 110.376 124.380 147.564 1.00 49.56  ? 388  TRP C O     1 
ATOM   12426 C  CB    . TRP C 2 373  ? 111.754 123.784 150.016 1.00 49.56  ? 388  TRP C CB    1 
ATOM   12427 C  CG    . TRP C 2 373  ? 111.348 122.361 149.837 1.00 49.56  ? 388  TRP C CG    1 
ATOM   12428 C  CD1   . TRP C 2 373  ? 110.095 121.896 149.575 1.00 49.56  ? 388  TRP C CD1   1 
ATOM   12429 C  CD2   . TRP C 2 373  ? 112.196 121.211 149.916 1.00 49.56  ? 388  TRP C CD2   1 
ATOM   12430 N  NE1   . TRP C 2 373  ? 110.108 120.526 149.483 1.00 49.56  ? 388  TRP C NE1   1 
ATOM   12431 C  CE2   . TRP C 2 373  ? 111.387 120.081 149.688 1.00 49.56  ? 388  TRP C CE2   1 
ATOM   12432 C  CE3   . TRP C 2 373  ? 113.560 121.027 150.155 1.00 49.56  ? 388  TRP C CE3   1 
ATOM   12433 C  CZ2   . TRP C 2 373  ? 111.896 118.786 149.692 1.00 49.56  ? 388  TRP C CZ2   1 
ATOM   12434 C  CZ3   . TRP C 2 373  ? 114.064 119.741 150.159 1.00 49.56  ? 388  TRP C CZ3   1 
ATOM   12435 C  CH2   . TRP C 2 373  ? 113.234 118.637 149.929 1.00 49.56  ? 388  TRP C CH2   1 
ATOM   12436 N  N     . PRO C 2 374  ? 112.199 123.709 146.449 1.00 52.78  ? 389  PRO C N     1 
ATOM   12437 C  CA    . PRO C 2 374  ? 111.429 123.526 145.213 1.00 52.78  ? 389  PRO C CA    1 
ATOM   12438 C  C     . PRO C 2 374  ? 110.548 122.291 145.261 1.00 52.78  ? 389  PRO C C     1 
ATOM   12439 O  O     . PRO C 2 374  ? 110.917 121.234 144.741 1.00 52.78  ? 389  PRO C O     1 
ATOM   12440 C  CB    . PRO C 2 374  ? 112.516 123.401 144.141 1.00 52.78  ? 389  PRO C CB    1 
ATOM   12441 C  CG    . PRO C 2 374  ? 113.685 122.848 144.871 1.00 52.78  ? 389  PRO C CG    1 
ATOM   12442 C  CD    . PRO C 2 374  ? 113.632 123.434 146.254 1.00 52.78  ? 389  PRO C CD    1 
ATOM   12443 N  N     . GLY C 2 375  ? 109.376 122.417 145.881 1.00 56.69  ? 390  GLY C N     1 
ATOM   12444 C  CA    . GLY C 2 375  ? 108.464 121.296 145.998 1.00 56.69  ? 390  GLY C CA    1 
ATOM   12445 C  C     . GLY C 2 375  ? 107.729 120.930 144.730 1.00 56.69  ? 390  GLY C C     1 
ATOM   12446 O  O     . GLY C 2 375  ? 107.064 119.890 144.693 1.00 56.69  ? 390  GLY C O     1 
ATOM   12447 N  N     . TYR C 2 376  ? 107.823 121.758 143.690 1.00 62.08  ? 391  TYR C N     1 
ATOM   12448 C  CA    . TYR C 2 376  ? 107.223 121.410 142.411 1.00 62.08  ? 391  TYR C CA    1 
ATOM   12449 C  C     . TYR C 2 376  ? 108.020 120.344 141.673 1.00 62.08  ? 391  TYR C C     1 
ATOM   12450 O  O     . TYR C 2 376  ? 107.476 119.692 140.775 1.00 62.08  ? 391  TYR C O     1 
ATOM   12451 C  CB    . TYR C 2 376  ? 107.085 122.657 141.535 1.00 62.08  ? 391  TYR C CB    1 
ATOM   12452 C  CG    . TYR C 2 376  ? 108.397 123.197 141.015 1.00 62.08  ? 391  TYR C CG    1 
ATOM   12453 C  CD1   . TYR C 2 376  ? 109.201 124.004 141.805 1.00 62.08  ? 391  TYR C CD1   1 
ATOM   12454 C  CD2   . TYR C 2 376  ? 108.825 122.907 139.729 1.00 62.08  ? 391  TYR C CD2   1 
ATOM   12455 C  CE1   . TYR C 2 376  ? 110.399 124.501 141.331 1.00 62.08  ? 391  TYR C CE1   1 
ATOM   12456 C  CE2   . TYR C 2 376  ? 110.020 123.398 139.246 1.00 62.08  ? 391  TYR C CE2   1 
ATOM   12457 C  CZ    . TYR C 2 376  ? 110.802 124.195 140.050 1.00 62.08  ? 391  TYR C CZ    1 
ATOM   12458 O  OH    . TYR C 2 376  ? 111.993 124.686 139.570 1.00 62.08  ? 391  TYR C OH    1 
ATOM   12459 N  N     . SER C 2 377  ? 109.287 120.155 142.032 1.00 61.36  ? 392  SER C N     1 
ATOM   12460 C  CA    . SER C 2 377  ? 110.136 119.130 141.440 1.00 61.36  ? 392  SER C CA    1 
ATOM   12461 C  C     . SER C 2 377  ? 109.969 117.769 142.101 1.00 61.36  ? 392  SER C C     1 
ATOM   12462 O  O     . SER C 2 377  ? 110.624 116.810 141.682 1.00 61.36  ? 392  SER C O     1 
ATOM   12463 C  CB    . SER C 2 377  ? 111.606 119.556 141.510 1.00 61.36  ? 392  SER C CB    1 
ATOM   12464 O  OG    . SER C 2 377  ? 111.824 120.765 140.804 1.00 61.36  ? 392  SER C OG    1 
ATOM   12465 N  N     . GLU C 2 378  ? 109.124 117.664 143.123 1.00 65.12  ? 393  GLU C N     1 
ATOM   12466 C  CA    . GLU C 2 378  ? 108.914 116.395 143.798 1.00 65.12  ? 393  GLU C CA    1 
ATOM   12467 C  C     . GLU C 2 378  ? 108.253 115.390 142.859 1.00 65.12  ? 393  GLU C C     1 
ATOM   12468 O  O     . GLU C 2 378  ? 107.630 115.749 141.856 1.00 65.12  ? 393  GLU C O     1 
ATOM   12469 C  CB    . GLU C 2 378  ? 108.057 116.585 145.049 1.00 65.12  ? 393  GLU C CB    1 
ATOM   12470 C  CG    . GLU C 2 378  ? 108.666 117.513 146.085 1.00 65.12  ? 393  GLU C CG    1 
ATOM   12471 C  CD    . GLU C 2 378  ? 107.735 117.769 147.253 1.00 65.12  ? 393  GLU C CD    1 
ATOM   12472 O  OE1   . GLU C 2 378  ? 106.739 117.029 147.394 1.00 65.12  ? 393  GLU C OE1   1 
ATOM   12473 O  OE2   . GLU C 2 378  ? 107.996 118.713 148.028 1.00 65.12  ? 393  GLU C OE2   1 
ATOM   12474 N  N     . THR C 2 379  ? 108.408 114.108 143.197 1.00 66.41  ? 394  THR C N     1 
ATOM   12475 C  CA    . THR C 2 379  ? 107.846 113.049 142.364 1.00 66.41  ? 394  THR C CA    1 
ATOM   12476 C  C     . THR C 2 379  ? 106.326 113.132 142.308 1.00 66.41  ? 394  THR C C     1 
ATOM   12477 O  O     . THR C 2 379  ? 105.727 112.979 141.237 1.00 66.41  ? 394  THR C O     1 
ATOM   12478 C  CB    . THR C 2 379  ? 108.289 111.683 142.886 1.00 66.41  ? 394  THR C CB    1 
ATOM   12479 O  OG1   . THR C 2 379  ? 107.875 111.535 144.250 1.00 66.41  ? 394  THR C OG1   1 
ATOM   12480 C  CG2   . THR C 2 379  ? 109.801 111.548 142.803 1.00 66.41  ? 394  THR C CG2   1 
ATOM   12481 N  N     . VAL C 2 380  ? 105.685 113.375 143.447 1.00 68.11  ? 395  VAL C N     1 
ATOM   12482 C  CA    . VAL C 2 380  ? 104.231 113.477 143.498 1.00 68.11  ? 395  VAL C CA    1 
ATOM   12483 C  C     . VAL C 2 380  ? 103.816 114.827 144.068 1.00 68.11  ? 395  VAL C C     1 
ATOM   12484 O  O     . VAL C 2 380  ? 103.896 115.053 145.276 1.00 68.11  ? 395  VAL C O     1 
ATOM   12485 C  CB    . VAL C 2 380  ? 103.619 112.330 144.321 1.00 68.11  ? 395  VAL C CB    1 
ATOM   12486 C  CG1   . VAL C 2 380  ? 102.102 112.448 144.344 1.00 68.11  ? 395  VAL C CG1   1 
ATOM   12487 C  CG2   . VAL C 2 380  ? 104.045 110.982 143.759 1.00 68.11  ? 395  VAL C CG2   1 
ATOM   12488 N  N     . SER C 2 383  ? 99.218  114.570 149.266 1.00 84.67  ? 398  SER C N     1 
ATOM   12489 C  CA    . SER C 2 383  ? 98.067  115.429 149.518 1.00 84.67  ? 398  SER C CA    1 
ATOM   12490 C  C     . SER C 2 383  ? 98.506  116.807 149.997 1.00 84.67  ? 398  SER C C     1 
ATOM   12491 O  O     . SER C 2 383  ? 99.638  116.987 150.446 1.00 84.67  ? 398  SER C O     1 
ATOM   12492 C  CB    . SER C 2 383  ? 97.132  114.789 150.546 1.00 84.67  ? 398  SER C CB    1 
ATOM   12493 O  OG    . SER C 2 383  ? 96.022  115.628 150.815 1.00 84.67  ? 398  SER C OG    1 
ATOM   12494 N  N     . LEU C 2 384  ? 97.598  117.780 149.892 1.00 83.23  ? 399  LEU C N     1 
ATOM   12495 C  CA    . LEU C 2 384  ? 97.913  119.140 150.318 1.00 83.23  ? 399  LEU C CA    1 
ATOM   12496 C  C     . LEU C 2 384  ? 98.159  119.206 151.821 1.00 83.23  ? 399  LEU C C     1 
ATOM   12497 O  O     . LEU C 2 384  ? 99.077  119.897 152.278 1.00 83.23  ? 399  LEU C O     1 
ATOM   12498 C  CB    . LEU C 2 384  ? 96.783  120.086 149.914 1.00 83.23  ? 399  LEU C CB    1 
ATOM   12499 C  CG    . LEU C 2 384  ? 97.101  121.581 149.896 1.00 83.23  ? 399  LEU C CG    1 
ATOM   12500 C  CD1   . LEU C 2 384  ? 98.176  121.885 148.864 1.00 83.23  ? 399  LEU C CD1   1 
ATOM   12501 C  CD2   . LEU C 2 384  ? 95.846  122.395 149.623 1.00 83.23  ? 399  LEU C CD2   1 
ATOM   12502 N  N     . GLU C 2 385  ? 97.346  118.494 152.606 1.00 83.14  ? 400  GLU C N     1 
ATOM   12503 C  CA    . GLU C 2 385  ? 97.534  118.477 154.054 1.00 83.14  ? 400  GLU C CA    1 
ATOM   12504 C  C     . GLU C 2 385  ? 98.854  117.818 154.433 1.00 83.14  ? 400  GLU C C     1 
ATOM   12505 O  O     . GLU C 2 385  ? 99.520  118.244 155.385 1.00 83.14  ? 400  GLU C O     1 
ATOM   12506 C  CB    . GLU C 2 385  ? 96.362  117.760 154.721 1.00 83.14  ? 400  GLU C CB    1 
ATOM   12507 C  CG    . GLU C 2 385  ? 95.003  118.338 154.366 1.00 83.14  ? 400  GLU C CG    1 
ATOM   12508 C  CD    . GLU C 2 385  ? 93.857  117.508 154.909 1.00 83.14  ? 400  GLU C CD    1 
ATOM   12509 O  OE1   . GLU C 2 385  ? 94.123  116.440 155.500 1.00 83.14  ? 400  GLU C OE1   1 
ATOM   12510 O  OE2   . GLU C 2 385  ? 92.691  117.923 154.744 1.00 83.14  ? 400  GLU C OE2   1 
ATOM   12511 N  N     . GLN C 2 386  ? 99.241  116.767 153.706 1.00 82.63  ? 401  GLN C N     1 
ATOM   12512 C  CA    . GLN C 2 386  ? 100.534 116.137 153.948 1.00 82.63  ? 401  GLN C CA    1 
ATOM   12513 C  C     . GLN C 2 386  ? 101.674 117.111 153.679 1.00 82.63  ? 401  GLN C C     1 
ATOM   12514 O  O     . GLN C 2 386  ? 102.647 117.165 154.440 1.00 82.63  ? 401  GLN C O     1 
ATOM   12515 C  CB    . GLN C 2 386  ? 100.677 114.888 153.080 1.00 82.63  ? 401  GLN C CB    1 
ATOM   12516 C  CG    . GLN C 2 386  ? 99.518  113.914 153.207 1.00 82.63  ? 401  GLN C CG    1 
ATOM   12517 C  CD    . GLN C 2 386  ? 99.626  112.753 152.240 1.00 82.63  ? 401  GLN C CD    1 
ATOM   12518 O  OE1   . GLN C 2 386  ? 100.687 112.503 151.667 1.00 82.63  ? 401  GLN C OE1   1 
ATOM   12519 N  NE2   . GLN C 2 386  ? 98.523  112.037 152.049 1.00 82.63  ? 401  GLN C NE2   1 
ATOM   12520 N  N     . LEU C 2 387  ? 101.569 117.888 152.598 1.00 77.38  ? 402  LEU C N     1 
ATOM   12521 C  CA    . LEU C 2 387  ? 102.575 118.907 152.319 1.00 77.38  ? 402  LEU C CA    1 
ATOM   12522 C  C     . LEU C 2 387  ? 102.603 119.966 153.412 1.00 77.38  ? 402  LEU C C     1 
ATOM   12523 O  O     . LEU C 2 387  ? 103.677 120.435 153.804 1.00 77.38  ? 402  LEU C O     1 
ATOM   12524 C  CB    . LEU C 2 387  ? 102.308 119.549 150.957 1.00 77.38  ? 402  LEU C CB    1 
ATOM   12525 C  CG    . LEU C 2 387  ? 102.425 118.626 149.744 1.00 77.38  ? 402  LEU C CG    1 
ATOM   12526 C  CD1   . LEU C 2 387  ? 102.052 119.366 148.470 1.00 77.38  ? 402  LEU C CD1   1 
ATOM   12527 C  CD2   . LEU C 2 387  ? 103.830 118.055 149.645 1.00 77.38  ? 402  LEU C CD2   1 
ATOM   12528 N  N     . HIS C 2 388  ? 101.428 120.365 153.907 1.00 76.83  ? 403  HIS C N     1 
ATOM   12529 C  CA    . HIS C 2 388  ? 101.370 121.319 155.011 1.00 76.83  ? 403  HIS C CA    1 
ATOM   12530 C  C     . HIS C 2 388  ? 102.116 120.789 156.227 1.00 76.83  ? 403  HIS C C     1 
ATOM   12531 O  O     . HIS C 2 388  ? 102.944 121.490 156.821 1.00 76.83  ? 403  HIS C O     1 
ATOM   12532 C  CB    . HIS C 2 388  ? 99.915  121.618 155.372 1.00 76.83  ? 403  HIS C CB    1 
ATOM   12533 C  CG    . HIS C 2 388  ? 99.129  122.242 154.263 1.00 76.83  ? 403  HIS C CG    1 
ATOM   12534 N  ND1   . HIS C 2 388  ? 97.751  122.250 154.242 1.00 76.83  ? 403  HIS C ND1   1 
ATOM   12535 C  CD2   . HIS C 2 388  ? 99.526  122.885 153.139 1.00 76.83  ? 403  HIS C CD2   1 
ATOM   12536 C  CE1   . HIS C 2 388  ? 97.333  122.868 153.153 1.00 76.83  ? 403  HIS C CE1   1 
ATOM   12537 N  NE2   . HIS C 2 388  ? 98.390  123.264 152.466 1.00 76.83  ? 403  HIS C NE2   1 
ATOM   12538 N  N     . SER C 2 389  ? 101.835 119.541 156.606 1.00 73.71  ? 404  SER C N     1 
ATOM   12539 C  CA    . SER C 2 389  ? 102.502 118.946 157.760 1.00 73.71  ? 404  SER C CA    1 
ATOM   12540 C  C     . SER C 2 389  ? 104.007 118.853 157.540 1.00 73.71  ? 404  SER C C     1 
ATOM   12541 O  O     . SER C 2 389  ? 104.794 119.152 158.446 1.00 73.71  ? 404  SER C O     1 
ATOM   12542 C  CB    . SER C 2 389  ? 101.916 117.565 158.049 1.00 73.71  ? 404  SER C CB    1 
ATOM   12543 O  OG    . SER C 2 389  ? 102.570 116.955 159.148 1.00 73.71  ? 404  SER C OG    1 
ATOM   12544 N  N     . LYS C 2 390  ? 104.424 118.440 156.341 1.00 69.42  ? 405  LYS C N     1 
ATOM   12545 C  CA    . LYS C 2 390  ? 105.848 118.307 156.054 1.00 69.42  ? 405  LYS C CA    1 
ATOM   12546 C  C     . LYS C 2 390  ? 106.557 119.651 156.137 1.00 69.42  ? 405  LYS C C     1 
ATOM   12547 O  O     . LYS C 2 390  ? 107.641 119.753 156.722 1.00 69.42  ? 405  LYS C O     1 
ATOM   12548 C  CB    . LYS C 2 390  ? 106.045 117.679 154.675 1.00 69.42  ? 405  LYS C CB    1 
ATOM   12549 C  CG    . LYS C 2 390  ? 107.496 117.583 154.237 1.00 69.42  ? 405  LYS C CG    1 
ATOM   12550 C  CD    . LYS C 2 390  ? 107.626 116.833 152.921 1.00 69.42  ? 405  LYS C CD    1 
ATOM   12551 C  CE    . LYS C 2 390  ? 106.812 117.496 151.822 1.00 69.42  ? 405  LYS C CE    1 
ATOM   12552 N  NZ    . LYS C 2 390  ? 106.897 116.741 150.542 1.00 69.42  ? 405  LYS C NZ    1 
ATOM   12553 N  N     . TYR C 2 391  ? 105.962 120.696 155.559 1.00 61.75  ? 406  TYR C N     1 
ATOM   12554 C  CA    . TYR C 2 391  ? 106.584 122.013 155.608 1.00 61.75  ? 406  TYR C CA    1 
ATOM   12555 C  C     . TYR C 2 391  ? 106.554 122.592 157.015 1.00 61.75  ? 406  TYR C C     1 
ATOM   12556 O  O     . TYR C 2 391  ? 107.412 123.411 157.364 1.00 61.75  ? 406  TYR C O     1 
ATOM   12557 C  CB    . TYR C 2 391  ? 105.895 122.956 154.621 1.00 61.75  ? 406  TYR C CB    1 
ATOM   12558 C  CG    . TYR C 2 391  ? 105.956 122.480 153.185 1.00 61.75  ? 406  TYR C CG    1 
ATOM   12559 C  CD1   . TYR C 2 391  ? 107.026 121.722 152.731 1.00 61.75  ? 406  TYR C CD1   1 
ATOM   12560 C  CD2   . TYR C 2 391  ? 104.942 122.783 152.288 1.00 61.75  ? 406  TYR C CD2   1 
ATOM   12561 C  CE1   . TYR C 2 391  ? 107.085 121.282 151.424 1.00 61.75  ? 406  TYR C CE1   1 
ATOM   12562 C  CE2   . TYR C 2 391  ? 104.993 122.344 150.978 1.00 61.75  ? 406  TYR C CE2   1 
ATOM   12563 C  CZ    . TYR C 2 391  ? 106.068 121.596 150.553 1.00 61.75  ? 406  TYR C CZ    1 
ATOM   12564 O  OH    . TYR C 2 391  ? 106.127 121.157 149.251 1.00 61.75  ? 406  TYR C OH    1 
ATOM   12565 N  N     . ASP C 2 392  ? 105.581 122.187 157.833 1.00 68.75  ? 407  ASP C N     1 
ATOM   12566 C  CA    . ASP C 2 392  ? 105.570 122.607 159.230 1.00 68.75  ? 407  ASP C CA    1 
ATOM   12567 C  C     . ASP C 2 392  ? 106.703 121.950 160.008 1.00 68.75  ? 407  ASP C C     1 
ATOM   12568 O  O     . ASP C 2 392  ? 107.414 122.615 160.770 1.00 68.75  ? 407  ASP C O     1 
ATOM   12569 C  CB    . ASP C 2 392  ? 104.219 122.281 159.867 1.00 68.75  ? 407  ASP C CB    1 
ATOM   12570 C  CG    . ASP C 2 392  ? 103.104 123.176 159.362 1.00 68.75  ? 407  ASP C CG    1 
ATOM   12571 O  OD1   . ASP C 2 392  ? 103.389 124.091 158.561 1.00 68.75  ? 407  ASP C OD1   1 
ATOM   12572 O  OD2   . ASP C 2 392  ? 101.942 122.965 159.768 1.00 68.75  ? 407  ASP C OD2   1 
ATOM   12573 N  N     . GLU C 2 393  ? 106.884 120.639 159.828 1.00 67.63  ? 408  GLU C N     1 
ATOM   12574 C  CA    . GLU C 2 393  ? 107.929 119.927 160.556 1.00 67.63  ? 408  GLU C CA    1 
ATOM   12575 C  C     . GLU C 2 393  ? 109.322 120.378 160.135 1.00 67.63  ? 408  GLU C C     1 
ATOM   12576 O  O     . GLU C 2 393  ? 110.250 120.360 160.951 1.00 67.63  ? 408  GLU C O     1 
ATOM   12577 C  CB    . GLU C 2 393  ? 107.776 118.421 160.353 1.00 67.63  ? 408  GLU C CB    1 
ATOM   12578 C  CG    . GLU C 2 393  ? 106.463 117.863 160.871 1.00 67.63  ? 408  GLU C CG    1 
ATOM   12579 C  CD    . GLU C 2 393  ? 106.225 116.432 160.432 1.00 67.63  ? 408  GLU C CD    1 
ATOM   12580 O  OE1   . GLU C 2 393  ? 107.044 115.904 159.653 1.00 67.63  ? 408  GLU C OE1   1 
ATOM   12581 O  OE2   . GLU C 2 393  ? 105.218 115.836 160.867 1.00 67.63  ? 408  GLU C OE2   1 
ATOM   12582 N  N     . MET C 2 394  ? 109.488 120.780 158.878 1.00 57.54  ? 409  MET C N     1 
ATOM   12583 C  CA    . MET C 2 394  ? 110.765 121.283 158.390 1.00 57.54  ? 409  MET C CA    1 
ATOM   12584 C  C     . MET C 2 394  ? 110.989 122.747 158.735 1.00 57.54  ? 409  MET C C     1 
ATOM   12585 O  O     . MET C 2 394  ? 112.042 123.293 158.386 1.00 57.54  ? 409  MET C O     1 
ATOM   12586 C  CB    . MET C 2 394  ? 110.860 121.092 156.874 1.00 57.54  ? 409  MET C CB    1 
ATOM   12587 C  CG    . MET C 2 394  ? 110.842 119.639 156.437 1.00 57.54  ? 409  MET C CG    1 
ATOM   12588 S  SD    . MET C 2 394  ? 110.568 119.446 154.667 1.00 57.54  ? 409  MET C SD    1 
ATOM   12589 C  CE    . MET C 2 394  ? 111.927 120.404 154.009 1.00 57.54  ? 409  MET C CE    1 
ATOM   12590 N  N     . SER C 2 395  ? 110.027 123.387 159.402 1.00 51.31  ? 410  SER C N     1 
ATOM   12591 C  CA    . SER C 2 395  ? 110.093 124.803 159.755 1.00 51.31  ? 410  SER C CA    1 
ATOM   12592 C  C     . SER C 2 395  ? 110.267 125.666 158.504 1.00 51.31  ? 410  SER C C     1 
ATOM   12593 O  O     . SER C 2 395  ? 111.265 126.368 158.327 1.00 51.31  ? 410  SER C O     1 
ATOM   12594 C  CB    . SER C 2 395  ? 111.208 125.070 160.771 1.00 51.31  ? 410  SER C CB    1 
ATOM   12595 O  OG    . SER C 2 395  ? 112.485 124.940 160.170 1.00 51.31  ? 410  SER C OG    1 
ATOM   12596 N  N     . VAL C 2 396  ? 109.271 125.592 157.628 1.00 46.38  ? 411  VAL C N     1 
ATOM   12597 C  CA    . VAL C 2 396  ? 109.210 126.425 156.435 1.00 46.38  ? 411  VAL C CA    1 
ATOM   12598 C  C     . VAL C 2 396  ? 108.257 127.573 156.729 1.00 46.38  ? 411  VAL C C     1 
ATOM   12599 O  O     . VAL C 2 396  ? 107.099 127.349 157.101 1.00 46.38  ? 411  VAL C O     1 
ATOM   12600 C  CB    . VAL C 2 396  ? 108.753 125.623 155.208 1.00 46.38  ? 411  VAL C CB    1 
ATOM   12601 C  CG1   . VAL C 2 396  ? 108.778 126.500 153.970 1.00 46.38  ? 411  VAL C CG1   1 
ATOM   12602 C  CG2   . VAL C 2 396  ? 109.633 124.399 155.019 1.00 46.38  ? 411  VAL C CG2   1 
ATOM   12603 N  N     . LEU C 2 397  ? 108.748 128.804 156.566 1.00 43.25  ? 412  LEU C N     1 
ATOM   12604 C  CA    . LEU C 2 397  ? 107.978 129.974 156.979 1.00 43.25  ? 412  LEU C CA    1 
ATOM   12605 C  C     . LEU C 2 397  ? 106.678 130.095 156.194 1.00 43.25  ? 412  LEU C C     1 
ATOM   12606 O  O     . LEU C 2 397  ? 105.620 130.371 156.772 1.00 43.25  ? 412  LEU C O     1 
ATOM   12607 C  CB    . LEU C 2 397  ? 108.818 131.239 156.809 1.00 43.25  ? 412  LEU C CB    1 
ATOM   12608 C  CG    . LEU C 2 397  ? 110.229 131.208 157.392 1.00 43.25  ? 412  LEU C CG    1 
ATOM   12609 C  CD1   . LEU C 2 397  ? 110.890 132.563 157.258 1.00 43.25  ? 412  LEU C CD1   1 
ATOM   12610 C  CD2   . LEU C 2 397  ? 110.186 130.779 158.839 1.00 43.25  ? 412  LEU C CD2   1 
ATOM   12611 N  N     . PHE C 2 398  ? 106.734 129.889 154.880 1.00 46.38  ? 413  PHE C N     1 
ATOM   12612 C  CA    . PHE C 2 398  ? 105.583 130.102 154.016 1.00 46.38  ? 413  PHE C CA    1 
ATOM   12613 C  C     . PHE C 2 398  ? 105.533 129.044 152.927 1.00 46.38  ? 413  PHE C C     1 
ATOM   12614 O  O     . PHE C 2 398  ? 106.554 128.726 152.311 1.00 46.38  ? 413  PHE C O     1 
ATOM   12615 C  CB    . PHE C 2 398  ? 105.620 131.492 153.376 1.00 46.38  ? 413  PHE C CB    1 
ATOM   12616 C  CG    . PHE C 2 398  ? 105.488 132.613 154.359 1.00 46.38  ? 413  PHE C CG    1 
ATOM   12617 C  CD1   . PHE C 2 398  ? 104.285 132.849 154.999 1.00 46.38  ? 413  PHE C CD1   1 
ATOM   12618 C  CD2   . PHE C 2 398  ? 106.564 133.436 154.638 1.00 46.38  ? 413  PHE C CD2   1 
ATOM   12619 C  CE1   . PHE C 2 398  ? 104.159 133.881 155.903 1.00 46.38  ? 413  PHE C CE1   1 
ATOM   12620 C  CE2   . PHE C 2 398  ? 106.443 134.472 155.540 1.00 46.38  ? 413  PHE C CE2   1 
ATOM   12621 C  CZ    . PHE C 2 398  ? 105.238 134.694 156.175 1.00 46.38  ? 413  PHE C CZ    1 
ATOM   12622 N  N     . SER C 2 399  ? 104.338 128.512 152.688 1.00 48.16  ? 414  SER C N     1 
ATOM   12623 C  CA    . SER C 2 399  ? 104.089 127.558 151.616 1.00 48.16  ? 414  SER C CA    1 
ATOM   12624 C  C     . SER C 2 399  ? 103.354 128.272 150.490 1.00 48.16  ? 414  SER C C     1 
ATOM   12625 O  O     . SER C 2 399  ? 102.246 128.780 150.694 1.00 48.16  ? 414  SER C O     1 
ATOM   12626 C  CB    . SER C 2 399  ? 103.277 126.366 152.122 1.00 48.16  ? 414  SER C CB    1 
ATOM   12627 O  OG    . SER C 2 399  ? 102.947 125.488 151.061 1.00 48.16  ? 414  SER C OG    1 
ATOM   12628 N  N     . VAL C 2 400  ? 103.969 128.309 149.311 1.00 52.13  ? 415  VAL C N     1 
ATOM   12629 C  CA    . VAL C 2 400  ? 103.408 128.974 148.140 1.00 52.13  ? 415  VAL C CA    1 
ATOM   12630 C  C     . VAL C 2 400  ? 102.795 127.921 147.231 1.00 52.13  ? 415  VAL C C     1 
ATOM   12631 O  O     . VAL C 2 400  ? 103.457 126.942 146.868 1.00 52.13  ? 415  VAL C O     1 
ATOM   12632 C  CB    . VAL C 2 400  ? 104.480 129.783 147.390 1.00 52.13  ? 415  VAL C CB    1 
ATOM   12633 C  CG1   . VAL C 2 400  ? 103.969 130.199 146.022 1.00 52.13  ? 415  VAL C CG1   1 
ATOM   12634 C  CG2   . VAL C 2 400  ? 104.894 130.996 148.197 1.00 52.13  ? 415  VAL C CG2   1 
ATOM   12635 N  N     . LEU C 2 401  ? 101.532 128.118 146.864 1.00 60.14  ? 416  LEU C N     1 
ATOM   12636 C  CA    . LEU C 2 401  ? 100.827 127.215 145.963 1.00 60.14  ? 416  LEU C CA    1 
ATOM   12637 C  C     . LEU C 2 401  ? 100.512 127.959 144.674 1.00 60.14  ? 416  LEU C C     1 
ATOM   12638 O  O     . LEU C 2 401  ? 99.822  128.983 144.698 1.00 60.14  ? 416  LEU C O     1 
ATOM   12639 C  CB    . LEU C 2 401  ? 99.546  126.681 146.608 1.00 60.14  ? 416  LEU C CB    1 
ATOM   12640 C  CG    . LEU C 2 401  ? 98.776  125.640 145.794 1.00 60.14  ? 416  LEU C CG    1 
ATOM   12641 C  CD1   . LEU C 2 401  ? 99.695  124.503 145.386 1.00 60.14  ? 416  LEU C CD1   1 
ATOM   12642 C  CD2   . LEU C 2 401  ? 97.588  125.109 146.580 1.00 60.14  ? 416  LEU C CD2   1 
ATOM   12643 N  N     . VAL C 2 402  ? 101.019 127.445 143.559 1.00 64.06  ? 417  VAL C N     1 
ATOM   12644 C  CA    . VAL C 2 402  ? 100.769 128.013 142.240 1.00 64.06  ? 417  VAL C CA    1 
ATOM   12645 C  C     . VAL C 2 402  ? 99.774  127.113 141.524 1.00 64.06  ? 417  VAL C C     1 
ATOM   12646 O  O     . VAL C 2 402  ? 100.032 125.919 141.330 1.00 64.06  ? 417  VAL C O     1 
ATOM   12647 C  CB    . VAL C 2 402  ? 102.068 128.157 141.432 1.00 64.06  ? 417  VAL C CB    1 
ATOM   12648 C  CG1   . VAL C 2 402  ? 101.756 128.530 139.992 1.00 64.06  ? 417  VAL C CG1   1 
ATOM   12649 C  CG2   . VAL C 2 402  ? 102.973 129.196 142.069 1.00 64.06  ? 417  VAL C CG2   1 
ATOM   12650 N  N     . THR C 2 403  ? 98.637  127.681 141.131 1.00 66.41  ? 418  THR C N     1 
ATOM   12651 C  CA    . THR C 2 403  ? 97.577  126.909 140.497 1.00 66.41  ? 418  THR C CA    1 
ATOM   12652 C  C     . THR C 2 403  ? 97.180  127.523 139.161 1.00 66.41  ? 418  THR C C     1 
ATOM   12653 O  O     . THR C 2 403  ? 97.846  128.439 138.669 1.00 66.41  ? 418  THR C O     1 
ATOM   12654 C  CB    . THR C 2 403  ? 96.358  126.815 141.416 1.00 66.41  ? 418  THR C CB    1 
ATOM   12655 O  OG1   . THR C 2 403  ? 95.973  128.130 141.834 1.00 66.41  ? 418  THR C OG1   1 
ATOM   12656 C  CG2   . THR C 2 403  ? 96.677  125.973 142.640 1.00 66.41  ? 418  THR C CG2   1 
ATOM   12657 N  N     . GLU C 2 404  ? 96.095  127.018 138.567 1.00 75.06  ? 419  GLU C N     1 
ATOM   12658 C  CA    . GLU C 2 404  ? 95.627  127.553 137.293 1.00 75.06  ? 419  GLU C CA    1 
ATOM   12659 C  C     . GLU C 2 404  ? 95.219  129.015 137.414 1.00 75.06  ? 419  GLU C C     1 
ATOM   12660 O  O     . GLU C 2 404  ? 95.324  129.771 136.442 1.00 75.06  ? 419  GLU C O     1 
ATOM   12661 C  CB    . GLU C 2 404  ? 94.458  126.716 136.775 1.00 75.06  ? 419  GLU C CB    1 
ATOM   12662 C  CG    . GLU C 2 404  ? 94.759  125.228 136.682 1.00 75.06  ? 419  GLU C CG    1 
ATOM   12663 C  CD    . GLU C 2 404  ? 93.539  124.405 136.316 1.00 75.06  ? 419  GLU C CD    1 
ATOM   12664 O  OE1   . GLU C 2 404  ? 92.458  124.997 136.115 1.00 75.06  ? 419  GLU C OE1   1 
ATOM   12665 O  OE2   . GLU C 2 404  ? 93.661  123.164 136.231 1.00 75.06  ? 419  GLU C OE2   1 
ATOM   12666 N  N     . THR C 2 405  ? 94.750  129.428 138.594 1.00 74.11  ? 420  THR C N     1 
ATOM   12667 C  CA    . THR C 2 405  ? 94.351  130.817 138.795 1.00 74.11  ? 420  THR C CA    1 
ATOM   12668 C  C     . THR C 2 405  ? 95.535  131.767 138.655 1.00 74.11  ? 420  THR C C     1 
ATOM   12669 O  O     . THR C 2 405  ? 95.353  132.938 138.300 1.00 74.11  ? 420  THR C O     1 
ATOM   12670 C  CB    . THR C 2 405  ? 93.694  130.975 140.167 1.00 74.11  ? 420  THR C CB    1 
ATOM   12671 O  OG1   . THR C 2 405  ? 92.734  129.929 140.357 1.00 74.11  ? 420  THR C OG1   1 
ATOM   12672 C  CG2   . THR C 2 405  ? 92.988  132.317 140.275 1.00 74.11  ? 420  THR C CG2   1 
ATOM   12673 N  N     . THR C 2 406  ? 96.752  131.285 138.920 1.00 71.26  ? 421  THR C N     1 
ATOM   12674 C  CA    . THR C 2 406  ? 97.936  132.120 138.756 1.00 71.26  ? 421  THR C CA    1 
ATOM   12675 C  C     . THR C 2 406  ? 98.132  132.559 137.313 1.00 71.26  ? 421  THR C C     1 
ATOM   12676 O  O     . THR C 2 406  ? 98.795  133.572 137.067 1.00 71.26  ? 421  THR C O     1 
ATOM   12677 C  CB    . THR C 2 406  ? 99.177  131.374 139.240 1.00 71.26  ? 421  THR C CB    1 
ATOM   12678 O  OG1   . THR C 2 406  ? 99.393  130.224 138.413 1.00 71.26  ? 421  THR C OG1   1 
ATOM   12679 C  CG2   . THR C 2 406  ? 98.987  130.922 140.674 1.00 71.26  ? 421  THR C CG2   1 
ATOM   12680 N  N     . LEU C 2 407  ? 97.586  131.814 136.355 1.00 76.55  ? 422  LEU C N     1 
ATOM   12681 C  CA    . LEU C 2 407  ? 97.572  132.249 134.966 1.00 76.55  ? 422  LEU C CA    1 
ATOM   12682 C  C     . LEU C 2 407  ? 96.396  133.173 134.678 1.00 76.55  ? 422  LEU C C     1 
ATOM   12683 O  O     . LEU C 2 407  ? 96.528  134.123 133.900 1.00 76.55  ? 422  LEU C O     1 
ATOM   12684 C  CB    . LEU C 2 407  ? 97.519  131.034 134.035 1.00 76.55  ? 422  LEU C CB    1 
ATOM   12685 C  CG    . LEU C 2 407  ? 98.596  129.969 134.249 1.00 76.55  ? 422  LEU C CG    1 
ATOM   12686 C  CD1   . LEU C 2 407  ? 98.336  128.759 133.366 1.00 76.55  ? 422  LEU C CD1   1 
ATOM   12687 C  CD2   . LEU C 2 407  ? 99.978  130.543 133.982 1.00 76.55  ? 422  LEU C CD2   1 
ATOM   12688 N  N     . GLU C 2 408  ? 95.246  132.907 135.299 1.00 82.06  ? 423  GLU C N     1 
ATOM   12689 C  CA    . GLU C 2 408  ? 94.053  133.709 135.056 1.00 82.06  ? 423  GLU C CA    1 
ATOM   12690 C  C     . GLU C 2 408  ? 94.112  135.053 135.773 1.00 82.06  ? 423  GLU C C     1 
ATOM   12691 O  O     . GLU C 2 408  ? 93.700  136.075 135.214 1.00 82.06  ? 423  GLU C O     1 
ATOM   12692 C  CB    . GLU C 2 408  ? 92.811  132.929 135.486 1.00 82.06  ? 423  GLU C CB    1 
ATOM   12693 C  CG    . GLU C 2 408  ? 92.734  131.532 134.894 1.00 82.06  ? 423  GLU C CG    1 
ATOM   12694 C  CD    . GLU C 2 408  ? 91.676  130.674 135.557 1.00 82.06  ? 423  GLU C CD    1 
ATOM   12695 O  OE1   . GLU C 2 408  ? 90.996  131.172 136.479 1.00 82.06  ? 423  GLU C OE1   1 
ATOM   12696 O  OE2   . GLU C 2 408  ? 91.526  129.500 135.158 1.00 82.06  ? 423  GLU C OE2   1 
ATOM   12697 N  N     . ASN C 2 409  ? 94.622  135.076 137.007 1.00 75.07  ? 424  ASN C N     1 
ATOM   12698 C  CA    . ASN C 2 409  ? 94.627  136.287 137.815 1.00 75.07  ? 424  ASN C CA    1 
ATOM   12699 C  C     . ASN C 2 409  ? 95.999  136.702 138.320 1.00 75.07  ? 424  ASN C C     1 
ATOM   12700 O  O     . ASN C 2 409  ? 96.159  137.858 138.727 1.00 75.07  ? 424  ASN C O     1 
ATOM   12701 C  CB    . ASN C 2 409  ? 93.697  136.127 139.029 1.00 75.07  ? 424  ASN C CB    1 
ATOM   12702 C  CG    . ASN C 2 409  ? 92.261  135.865 138.632 1.00 75.07  ? 424  ASN C CG    1 
ATOM   12703 O  OD1   . ASN C 2 409  ? 91.837  136.210 137.530 1.00 75.07  ? 424  ASN C OD1   1 
ATOM   12704 N  ND2   . ASN C 2 409  ? 91.501  135.255 139.534 1.00 75.07  ? 424  ASN C ND2   1 
ATOM   12705 N  N     . GLY C 2 410  ? 96.986  135.810 138.308 1.00 64.30  ? 425  GLY C N     1 
ATOM   12706 C  CA    . GLY C 2 410  ? 98.284  136.137 138.861 1.00 64.30  ? 425  GLY C CA    1 
ATOM   12707 C  C     . GLY C 2 410  ? 98.342  136.141 140.369 1.00 64.30  ? 425  GLY C C     1 
ATOM   12708 O  O     . GLY C 2 410  ? 99.252  136.748 140.941 1.00 64.30  ? 425  GLY C O     1 
ATOM   12709 N  N     . LEU C 2 411  ? 97.400  135.479 141.033 1.00 65.73  ? 426  LEU C N     1 
ATOM   12710 C  CA    . LEU C 2 411  ? 97.345  135.418 142.486 1.00 65.73  ? 426  LEU C CA    1 
ATOM   12711 C  C     . LEU C 2 411  ? 97.795  134.041 142.951 1.00 65.73  ? 426  LEU C C     1 
ATOM   12712 O  O     . LEU C 2 411  ? 97.283  133.022 142.477 1.00 65.73  ? 426  LEU C O     1 
ATOM   12713 C  CB    . LEU C 2 411  ? 95.932  135.711 142.996 1.00 65.73  ? 426  LEU C CB    1 
ATOM   12714 C  CG    . LEU C 2 411  ? 95.375  137.108 142.723 1.00 65.73  ? 426  LEU C CG    1 
ATOM   12715 C  CD1   . LEU C 2 411  ? 94.001  137.259 143.353 1.00 65.73  ? 426  LEU C CD1   1 
ATOM   12716 C  CD2   . LEU C 2 411  ? 96.325  138.175 143.241 1.00 65.73  ? 426  LEU C CD2   1 
ATOM   12717 N  N     . ILE C 2 412  ? 98.747  134.017 143.879 1.00 60.03  ? 427  ILE C N     1 
ATOM   12718 C  CA    . ILE C 2 412  ? 99.311  132.783 144.414 1.00 60.03  ? 427  ILE C CA    1 
ATOM   12719 C  C     . ILE C 2 412  ? 98.830  132.613 145.846 1.00 60.03  ? 427  ILE C C     1 
ATOM   12720 O  O     . ILE C 2 412  ? 98.861  133.564 146.636 1.00 60.03  ? 427  ILE C O     1 
ATOM   12721 C  CB    . ILE C 2 412  ? 100.848 132.791 144.350 1.00 60.03  ? 427  ILE C CB    1 
ATOM   12722 C  CG1   . ILE C 2 412  ? 101.388 134.155 144.776 1.00 60.03  ? 427  ILE C CG1   1 
ATOM   12723 C  CG2   . ILE C 2 412  ? 101.330 132.431 142.958 1.00 60.03  ? 427  ILE C CG2   1 
ATOM   12724 C  CD1   . ILE C 2 412  ? 102.866 134.310 144.572 1.00 60.03  ? 427  ILE C CD1   1 
ATOM   12725 N  N     . GLN C 2 413  ? 98.377  131.407 146.175 1.00 63.41  ? 428  GLN C N     1 
ATOM   12726 C  CA    . GLN C 2 413  ? 97.994  131.107 147.547 1.00 63.41  ? 428  GLN C CA    1 
ATOM   12727 C  C     . GLN C 2 413  ? 99.229  131.087 148.437 1.00 63.41  ? 428  GLN C C     1 
ATOM   12728 O  O     . GLN C 2 413  ? 100.226 130.433 148.119 1.00 63.41  ? 428  GLN C O     1 
ATOM   12729 C  CB    . GLN C 2 413  ? 97.272  129.765 147.615 1.00 63.41  ? 428  GLN C CB    1 
ATOM   12730 C  CG    . GLN C 2 413  ? 97.115  129.229 149.024 1.00 63.41  ? 428  GLN C CG    1 
ATOM   12731 C  CD    . GLN C 2 413  ? 96.508  127.845 149.050 1.00 63.41  ? 428  GLN C CD    1 
ATOM   12732 O  OE1   . GLN C 2 413  ? 95.864  127.421 148.092 1.00 63.41  ? 428  GLN C OE1   1 
ATOM   12733 N  NE2   . GLN C 2 413  ? 96.714  127.129 150.149 1.00 63.41  ? 428  GLN C NE2   1 
ATOM   12734 N  N     . LEU C 2 414  ? 99.163  131.806 149.553 1.00 57.05  ? 429  LEU C N     1 
ATOM   12735 C  CA    . LEU C 2 414  ? 100.271 131.898 150.493 1.00 57.05  ? 429  LEU C CA    1 
ATOM   12736 C  C     . LEU C 2 414  ? 99.781  131.481 151.871 1.00 57.05  ? 429  LEU C C     1 
ATOM   12737 O  O     . LEU C 2 414  ? 98.795  132.029 152.376 1.00 57.05  ? 429  LEU C O     1 
ATOM   12738 C  CB    . LEU C 2 414  ? 100.846 133.313 150.525 1.00 57.05  ? 429  LEU C CB    1 
ATOM   12739 C  CG    . LEU C 2 414  ? 102.113 133.480 151.358 1.00 57.05  ? 429  LEU C CG    1 
ATOM   12740 C  CD1   . LEU C 2 414  ? 103.107 132.397 151.000 1.00 57.05  ? 429  LEU C CD1   1 
ATOM   12741 C  CD2   . LEU C 2 414  ? 102.713 134.847 151.122 1.00 57.05  ? 429  LEU C CD2   1 
ATOM   12742 N  N     . ARG C 2 415  ? 100.469 130.518 152.475 1.00 59.67  ? 430  ARG C N     1 
ATOM   12743 C  CA    . ARG C 2 415  ? 100.112 129.986 153.781 1.00 59.67  ? 430  ARG C CA    1 
ATOM   12744 C  C     . ARG C 2 415  ? 101.259 130.222 154.750 1.00 59.67  ? 430  ARG C C     1 
ATOM   12745 O  O     . ARG C 2 415  ? 102.426 130.013 154.406 1.00 59.67  ? 430  ARG C O     1 
ATOM   12746 C  CB    . ARG C 2 415  ? 99.789  128.494 153.692 1.00 59.67  ? 430  ARG C CB    1 
ATOM   12747 C  CG    . ARG C 2 415  ? 99.381  127.864 155.005 1.00 59.67  ? 430  ARG C CG    1 
ATOM   12748 C  CD    . ARG C 2 415  ? 99.211  126.366 154.852 1.00 59.67  ? 430  ARG C CD    1 
ATOM   12749 N  NE    . ARG C 2 415  ? 98.790  125.736 156.096 1.00 59.67  ? 430  ARG C NE    1 
ATOM   12750 C  CZ    . ARG C 2 415  ? 99.619  125.345 157.054 1.00 59.67  ? 430  ARG C CZ    1 
ATOM   12751 N  NH1   . ARG C 2 415  ? 100.926 125.517 156.949 1.00 59.67  ? 430  ARG C NH1   1 
ATOM   12752 N  NH2   . ARG C 2 415  ? 99.123  124.768 158.144 1.00 59.67  ? 430  ARG C NH2   1 
ATOM   12753 N  N     . SER C 2 416  ? 100.926 130.659 155.960 1.00 64.34  ? 431  SER C N     1 
ATOM   12754 C  CA    . SER C 2 416  ? 101.920 131.031 156.958 1.00 64.34  ? 431  SER C CA    1 
ATOM   12755 C  C     . SER C 2 416  ? 102.059 129.925 157.993 1.00 64.34  ? 431  SER C C     1 
ATOM   12756 O  O     . SER C 2 416  ? 101.057 129.385 158.470 1.00 64.34  ? 431  SER C O     1 
ATOM   12757 C  CB    . SER C 2 416  ? 101.536 132.342 157.644 1.00 64.34  ? 431  SER C CB    1 
ATOM   12758 O  OG    . SER C 2 416  ? 100.325 132.200 158.363 1.00 64.34  ? 431  SER C OG    1 
ATOM   12759 N  N     . ARG C 2 417  ? 103.304 129.587 158.332 1.00 58.19  ? 432  ARG C N     1 
ATOM   12760 C  CA    . ARG C 2 417  ? 103.542 128.613 159.391 1.00 58.19  ? 432  ARG C CA    1 
ATOM   12761 C  C     . ARG C 2 417  ? 103.069 129.140 160.741 1.00 58.19  ? 432  ARG C C     1 
ATOM   12762 O  O     . ARG C 2 417  ? 102.500 128.388 161.542 1.00 58.19  ? 432  ARG C O     1 
ATOM   12763 C  CB    . ARG C 2 417  ? 105.026 128.247 159.440 1.00 58.19  ? 432  ARG C CB    1 
ATOM   12764 C  CG    . ARG C 2 417  ? 105.458 127.545 160.717 1.00 58.19  ? 432  ARG C CG    1 
ATOM   12765 C  CD    . ARG C 2 417  ? 106.282 128.469 161.597 1.00 58.19  ? 432  ARG C CD    1 
ATOM   12766 N  NE    . ARG C 2 417  ? 107.711 128.343 161.341 1.00 58.19  ? 432  ARG C NE    1 
ATOM   12767 C  CZ    . ARG C 2 417  ? 108.621 129.219 161.740 1.00 58.19  ? 432  ARG C CZ    1 
ATOM   12768 N  NH1   . ARG C 2 417  ? 108.281 130.326 162.379 1.00 58.19  ? 432  ARG C NH1   1 
ATOM   12769 N  NH2   . ARG C 2 417  ? 109.905 128.979 161.492 1.00 58.19  ? 432  ARG C NH2   1 
ATOM   12770 N  N     . ASP C 2 418  ? 103.290 130.431 161.007 1.00 71.65  ? 433  ASP C N     1 
ATOM   12771 C  CA    . ASP C 2 418  ? 102.960 130.994 162.312 1.00 71.65  ? 433  ASP C CA    1 
ATOM   12772 C  C     . ASP C 2 418  ? 101.464 130.950 162.597 1.00 71.65  ? 433  ASP C C     1 
ATOM   12773 O  O     . ASP C 2 418  ? 101.059 130.650 163.726 1.00 71.65  ? 433  ASP C O     1 
ATOM   12774 C  CB    . ASP C 2 418  ? 103.472 132.433 162.409 1.00 71.65  ? 433  ASP C CB    1 
ATOM   12775 C  CG    . ASP C 2 418  ? 104.985 132.510 162.494 1.00 71.65  ? 433  ASP C CG    1 
ATOM   12776 O  OD1   . ASP C 2 418  ? 105.606 131.539 162.975 1.00 71.65  ? 433  ASP C OD1   1 
ATOM   12777 O  OD2   . ASP C 2 418  ? 105.554 133.544 162.085 1.00 71.65  ? 433  ASP C OD2   1 
ATOM   12778 N  N     . THR C 2 419  ? 100.627 131.243 161.600 1.00 69.31  ? 434  THR C N     1 
ATOM   12779 C  CA    . THR C 2 419  ? 99.190  131.330 161.809 1.00 69.31  ? 434  THR C CA    1 
ATOM   12780 C  C     . THR C 2 419  ? 98.393  130.217 161.145 1.00 69.31  ? 434  THR C C     1 
ATOM   12781 O  O     . THR C 2 419  ? 97.218  130.043 161.488 1.00 69.31  ? 434  THR C O     1 
ATOM   12782 C  CB    . THR C 2 419  ? 98.653  132.682 161.311 1.00 69.31  ? 434  THR C CB    1 
ATOM   12783 O  OG1   . THR C 2 419  ? 98.793  132.759 159.887 1.00 69.31  ? 434  THR C OG1   1 
ATOM   12784 C  CG2   . THR C 2 419  ? 99.421  133.827 161.951 1.00 69.31  ? 434  THR C CG2   1 
ATOM   12785 N  N     . THR C 2 420  ? 98.989  129.463 160.220 1.00 67.67  ? 435  THR C N     1 
ATOM   12786 C  CA    . THR C 2 420  ? 98.304  128.375 159.515 1.00 67.67  ? 435  THR C CA    1 
ATOM   12787 C  C     . THR C 2 420  ? 97.028  128.867 158.836 1.00 67.67  ? 435  THR C C     1 
ATOM   12788 O  O     . THR C 2 420  ? 95.974  128.231 158.906 1.00 67.67  ? 435  THR C O     1 
ATOM   12789 C  CB    . THR C 2 420  ? 98.005  127.205 160.456 1.00 67.67  ? 435  THR C CB    1 
ATOM   12790 O  OG1   . THR C 2 420  ? 96.995  127.587 161.398 1.00 67.67  ? 435  THR C OG1   1 
ATOM   12791 C  CG2   . THR C 2 420  ? 99.263  126.796 161.209 1.00 67.67  ? 435  THR C CG2   1 
ATOM   12792 N  N     . MET C 2 421  ? 97.126  130.013 158.166 1.00 69.47  ? 436  MET C N     1 
ATOM   12793 C  CA    . MET C 2 421  ? 96.003  130.605 157.458 1.00 69.47  ? 436  MET C CA    1 
ATOM   12794 C  C     . MET C 2 421  ? 96.407  130.909 156.021 1.00 69.47  ? 436  MET C C     1 
ATOM   12795 O  O     . MET C 2 421  ? 97.585  131.102 155.711 1.00 69.47  ? 436  MET C O     1 
ATOM   12796 C  CB    . MET C 2 421  ? 95.508  131.882 158.151 1.00 69.47  ? 436  MET C CB    1 
ATOM   12797 C  CG    . MET C 2 421  ? 95.065  131.670 159.590 1.00 69.47  ? 436  MET C CG    1 
ATOM   12798 S  SD    . MET C 2 421  ? 93.764  130.432 159.746 1.00 69.47  ? 436  MET C SD    1 
ATOM   12799 C  CE    . MET C 2 421  ? 93.610  130.330 161.528 1.00 69.47  ? 436  MET C CE    1 
ATOM   12800 N  N     . LYS C 2 422  ? 95.408  130.954 155.145 1.00 64.37  ? 437  LYS C N     1 
ATOM   12801 C  CA    . LYS C 2 422  ? 95.622  131.120 153.714 1.00 64.37  ? 437  LYS C CA    1 
ATOM   12802 C  C     . LYS C 2 422  ? 95.485  132.583 153.313 1.00 64.37  ? 437  LYS C C     1 
ATOM   12803 O  O     . LYS C 2 422  ? 94.583  133.286 153.779 1.00 64.37  ? 437  LYS C O     1 
ATOM   12804 C  CB    . LYS C 2 422  ? 94.634  130.268 152.918 1.00 64.37  ? 437  LYS C CB    1 
ATOM   12805 C  CG    . LYS C 2 422  ? 94.825  128.773 153.103 1.00 64.37  ? 437  LYS C CG    1 
ATOM   12806 C  CD    . LYS C 2 422  ? 93.737  127.987 152.393 1.00 64.37  ? 437  LYS C CD    1 
ATOM   12807 C  CE    . LYS C 2 422  ? 93.646  128.373 150.927 1.00 64.37  ? 437  LYS C CE    1 
ATOM   12808 N  NZ    . LYS C 2 422  ? 92.577  127.616 150.219 1.00 64.37  ? 437  LYS C NZ    1 
ATOM   12809 N  N     . GLU C 2 423  ? 96.388  133.035 152.446 1.00 63.85  ? 438  GLU C N     1 
ATOM   12810 C  CA    . GLU C 2 423  ? 96.391  134.403 151.952 1.00 63.85  ? 438  GLU C CA    1 
ATOM   12811 C  C     . GLU C 2 423  ? 96.652  134.391 150.452 1.00 63.85  ? 438  GLU C C     1 
ATOM   12812 O  O     . GLU C 2 423  ? 97.362  133.522 149.938 1.00 63.85  ? 438  GLU C O     1 
ATOM   12813 C  CB    . GLU C 2 423  ? 97.449  135.252 152.673 1.00 63.85  ? 438  GLU C CB    1 
ATOM   12814 C  CG    . GLU C 2 423  ? 97.520  136.702 152.223 1.00 63.85  ? 438  GLU C CG    1 
ATOM   12815 C  CD    . GLU C 2 423  ? 98.668  137.455 152.864 1.00 63.85  ? 438  GLU C CD    1 
ATOM   12816 O  OE1   . GLU C 2 423  ? 99.152  137.011 153.927 1.00 63.85  ? 438  GLU C OE1   1 
ATOM   12817 O  OE2   . GLU C 2 423  ? 99.090  138.487 152.303 1.00 63.85  ? 438  GLU C OE2   1 
ATOM   12818 N  N     . MET C 2 424  ? 96.070  135.362 149.755 1.00 65.82  ? 439  MET C N     1 
ATOM   12819 C  CA    . MET C 2 424  ? 96.239  135.516 148.317 1.00 65.82  ? 439  MET C CA    1 
ATOM   12820 C  C     . MET C 2 424  ? 97.024  136.787 148.023 1.00 65.82  ? 439  MET C C     1 
ATOM   12821 O  O     . MET C 2 424  ? 96.762  137.840 148.612 1.00 65.82  ? 439  MET C O     1 
ATOM   12822 C  CB    . MET C 2 424  ? 94.884  135.563 147.607 1.00 65.82  ? 439  MET C CB    1 
ATOM   12823 C  CG    . MET C 2 424  ? 94.039  134.315 147.800 1.00 65.82  ? 439  MET C CG    1 
ATOM   12824 S  SD    . MET C 2 424  ? 94.803  132.843 147.092 1.00 65.82  ? 439  MET C SD    1 
ATOM   12825 C  CE    . MET C 2 424  ? 93.579  131.597 147.490 1.00 65.82  ? 439  MET C CE    1 
ATOM   12826 N  N     . MET C 2 425  ? 97.988  136.682 147.112 1.00 58.95  ? 440  MET C N     1 
ATOM   12827 C  CA    . MET C 2 425  ? 98.838  137.811 146.765 1.00 58.95  ? 440  MET C CA    1 
ATOM   12828 C  C     . MET C 2 425  ? 99.255  137.692 145.307 1.00 58.95  ? 440  MET C C     1 
ATOM   12829 O  O     . MET C 2 425  ? 99.344  136.590 144.761 1.00 58.95  ? 440  MET C O     1 
ATOM   12830 C  CB    . MET C 2 425  ? 100.071 137.874 147.676 1.00 58.95  ? 440  MET C CB    1 
ATOM   12831 C  CG    . MET C 2 425  ? 100.989 139.057 147.424 1.00 58.95  ? 440  MET C CG    1 
ATOM   12832 S  SD    . MET C 2 425  ? 102.404 139.073 148.535 1.00 58.95  ? 440  MET C SD    1 
ATOM   12833 C  CE    . MET C 2 425  ? 101.573 139.180 150.116 1.00 58.95  ? 440  MET C CE    1 
ATOM   12834 N  N     . HIS C 2 426  ? 99.505  138.839 144.680 1.00 56.68  ? 441  HIS C N     1 
ATOM   12835 C  CA    . HIS C 2 426  ? 100.011 138.848 143.316 1.00 56.68  ? 441  HIS C CA    1 
ATOM   12836 C  C     . HIS C 2 426  ? 101.457 138.364 143.284 1.00 56.68  ? 441  HIS C C     1 
ATOM   12837 O  O     . HIS C 2 426  ? 102.226 138.567 144.227 1.00 56.68  ? 441  HIS C O     1 
ATOM   12838 C  CB    . HIS C 2 426  ? 99.909  140.250 142.715 1.00 56.68  ? 441  HIS C CB    1 
ATOM   12839 C  CG    . HIS C 2 426  ? 100.234 140.305 141.255 1.00 56.68  ? 441  HIS C CG    1 
ATOM   12840 N  ND1   . HIS C 2 426  ? 101.346 140.954 140.763 1.00 56.68  ? 441  HIS C ND1   1 
ATOM   12841 C  CD2   . HIS C 2 426  ? 99.595  139.785 140.181 1.00 56.68  ? 441  HIS C CD2   1 
ATOM   12842 C  CE1   . HIS C 2 426  ? 101.376 140.835 139.448 1.00 56.68  ? 441  HIS C CE1   1 
ATOM   12843 N  NE2   . HIS C 2 426  ? 100.325 140.130 139.069 1.00 56.68  ? 441  HIS C NE2   1 
ATOM   12844 N  N     . ILE C 2 427  ? 101.821 137.713 142.176 1.00 55.82  ? 442  ILE C N     1 
ATOM   12845 C  CA    . ILE C 2 427  ? 103.137 137.085 142.071 1.00 55.82  ? 442  ILE C CA    1 
ATOM   12846 C  C     . ILE C 2 427  ? 104.245 138.128 142.144 1.00 55.82  ? 442  ILE C C     1 
ATOM   12847 O  O     . ILE C 2 427  ? 105.265 137.923 142.814 1.00 55.82  ? 442  ILE C O     1 
ATOM   12848 C  CB    . ILE C 2 427  ? 103.229 136.254 140.778 1.00 55.82  ? 442  ILE C CB    1 
ATOM   12849 C  CG1   . ILE C 2 427  ? 102.189 135.133 140.791 1.00 55.82  ? 442  ILE C CG1   1 
ATOM   12850 C  CG2   . ILE C 2 427  ? 104.628 135.687 140.606 1.00 55.82  ? 442  ILE C CG2   1 
ATOM   12851 C  CD1   . ILE C 2 427  ? 102.298 134.180 139.620 1.00 55.82  ? 442  ILE C CD1   1 
ATOM   12852 N  N     . SER C 2 428  ? 104.068 139.260 141.458 1.00 54.01  ? 443  SER C N     1 
ATOM   12853 C  CA    . SER C 2 428  ? 105.116 140.273 141.407 1.00 54.01  ? 443  SER C CA    1 
ATOM   12854 C  C     . SER C 2 428  ? 105.427 140.865 142.775 1.00 54.01  ? 443  SER C C     1 
ATOM   12855 O  O     . SER C 2 428  ? 106.516 141.417 142.965 1.00 54.01  ? 443  SER C O     1 
ATOM   12856 C  CB    . SER C 2 428  ? 104.722 141.392 140.442 1.00 54.01  ? 443  SER C CB    1 
ATOM   12857 O  OG    . SER C 2 428  ? 105.701 142.417 140.426 1.00 54.01  ? 443  SER C OG    1 
ATOM   12858 N  N     . LYS C 2 429  ? 104.504 140.765 143.728 1.00 55.59  ? 444  LYS C N     1 
ATOM   12859 C  CA    . LYS C 2 429  ? 104.691 141.333 145.054 1.00 55.59  ? 444  LYS C CA    1 
ATOM   12860 C  C     . LYS C 2 429  ? 105.009 140.282 146.110 1.00 55.59  ? 444  LYS C C     1 
ATOM   12861 O  O     . LYS C 2 429  ? 105.054 140.610 147.300 1.00 55.59  ? 444  LYS C O     1 
ATOM   12862 C  CB    . LYS C 2 429  ? 103.449 142.129 145.456 1.00 55.59  ? 444  LYS C CB    1 
ATOM   12863 C  CG    . LYS C 2 429  ? 103.083 143.216 144.459 1.00 55.59  ? 444  LYS C CG    1 
ATOM   12864 C  CD    . LYS C 2 429  ? 101.813 143.940 144.862 1.00 55.59  ? 444  LYS C CD    1 
ATOM   12865 C  CE    . LYS C 2 429  ? 101.427 144.983 143.828 1.00 55.59  ? 444  LYS C CE    1 
ATOM   12866 N  NZ    . LYS C 2 429  ? 100.184 145.704 144.212 1.00 55.59  ? 444  LYS C NZ    1 
ATOM   12867 N  N     . LEU C 2 430  ? 105.233 139.030 145.707 1.00 52.75  ? 445  LEU C N     1 
ATOM   12868 C  CA    . LEU C 2 430  ? 105.603 138.002 146.675 1.00 52.75  ? 445  LEU C CA    1 
ATOM   12869 C  C     . LEU C 2 430  ? 107.028 138.201 147.173 1.00 52.75  ? 445  LEU C C     1 
ATOM   12870 O  O     . LEU C 2 430  ? 107.300 138.054 148.370 1.00 52.75  ? 445  LEU C O     1 
ATOM   12871 C  CB    . LEU C 2 430  ? 105.446 136.612 146.060 1.00 52.75  ? 445  LEU C CB    1 
ATOM   12872 C  CG    . LEU C 2 430  ? 105.626 135.445 147.032 1.00 52.75  ? 445  LEU C CG    1 
ATOM   12873 C  CD1   . LEU C 2 430  ? 104.364 135.237 147.854 1.00 52.75  ? 445  LEU C CD1   1 
ATOM   12874 C  CD2   . LEU C 2 430  ? 106.018 134.171 146.302 1.00 52.75  ? 445  LEU C CD2   1 
ATOM   12875 N  N     . ARG C 2 431  ? 107.951 138.526 146.265 1.00 53.36  ? 446  ARG C N     1 
ATOM   12876 C  CA    . ARG C 2 431  ? 109.342 138.734 146.653 1.00 53.36  ? 446  ARG C CA    1 
ATOM   12877 C  C     . ARG C 2 431  ? 109.468 139.874 147.653 1.00 53.36  ? 446  ARG C C     1 
ATOM   12878 O  O     . ARG C 2 431  ? 110.155 139.749 148.675 1.00 53.36  ? 446  ARG C O     1 
ATOM   12879 C  CB    . ARG C 2 431  ? 110.189 139.010 145.409 1.00 53.36  ? 446  ARG C CB    1 
ATOM   12880 C  CG    . ARG C 2 431  ? 111.619 139.440 145.698 1.00 53.36  ? 446  ARG C CG    1 
ATOM   12881 C  CD    . ARG C 2 431  ? 111.782 140.956 145.673 1.00 53.36  ? 446  ARG C CD    1 
ATOM   12882 N  NE    . ARG C 2 431  ? 113.099 141.373 146.141 1.00 53.36  ? 446  ARG C NE    1 
ATOM   12883 C  CZ    . ARG C 2 431  ? 113.414 142.616 146.479 1.00 53.36  ? 446  ARG C CZ    1 
ATOM   12884 N  NH1   . ARG C 2 431  ? 112.525 143.594 146.426 1.00 53.36  ? 446  ARG C NH1   1 
ATOM   12885 N  NH2   . ARG C 2 431  ? 114.652 142.884 146.885 1.00 53.36  ? 446  ARG C NH2   1 
ATOM   12886 N  N     . ASP C 2 432  ? 108.817 141.003 147.366 1.00 56.77  ? 447  ASP C N     1 
ATOM   12887 C  CA    . ASP C 2 432  ? 108.895 142.145 148.269 1.00 56.77  ? 447  ASP C CA    1 
ATOM   12888 C  C     . ASP C 2 432  ? 108.266 141.819 149.615 1.00 56.77  ? 447  ASP C C     1 
ATOM   12889 O  O     . ASP C 2 432  ? 108.790 142.212 150.663 1.00 56.77  ? 447  ASP C O     1 
ATOM   12890 C  CB    . ASP C 2 432  ? 108.218 143.362 147.641 1.00 56.77  ? 447  ASP C CB    1 
ATOM   12891 C  CG    . ASP C 2 432  ? 108.481 144.636 148.416 1.00 56.77  ? 447  ASP C CG    1 
ATOM   12892 O  OD1   . ASP C 2 432  ? 109.390 144.635 149.274 1.00 56.77  ? 447  ASP C OD1   1 
ATOM   12893 O  OD2   . ASP C 2 432  ? 107.777 145.638 148.173 1.00 56.77  ? 447  ASP C OD2   1 
ATOM   12894 N  N     . PHE C 2 433  ? 107.144 141.096 149.607 1.00 53.38  ? 448  PHE C N     1 
ATOM   12895 C  CA    . PHE C 2 433  ? 106.509 140.706 150.861 1.00 53.38  ? 448  PHE C CA    1 
ATOM   12896 C  C     . PHE C 2 433  ? 107.426 139.821 151.693 1.00 53.38  ? 448  PHE C C     1 
ATOM   12897 O  O     . PHE C 2 433  ? 107.535 140.001 152.910 1.00 53.38  ? 448  PHE C O     1 
ATOM   12898 C  CB    . PHE C 2 433  ? 105.190 139.988 150.587 1.00 53.38  ? 448  PHE C CB    1 
ATOM   12899 C  CG    . PHE C 2 433  ? 104.639 139.263 151.781 1.00 53.38  ? 448  PHE C CG    1 
ATOM   12900 C  CD1   . PHE C 2 433  ? 103.921 139.943 152.750 1.00 53.38  ? 448  PHE C CD1   1 
ATOM   12901 C  CD2   . PHE C 2 433  ? 104.836 137.901 151.936 1.00 53.38  ? 448  PHE C CD2   1 
ATOM   12902 C  CE1   . PHE C 2 433  ? 103.413 139.279 153.850 1.00 53.38  ? 448  PHE C CE1   1 
ATOM   12903 C  CE2   . PHE C 2 433  ? 104.333 137.234 153.034 1.00 53.38  ? 448  PHE C CE2   1 
ATOM   12904 C  CZ    . PHE C 2 433  ? 103.619 137.923 153.991 1.00 53.38  ? 448  PHE C CZ    1 
ATOM   12905 N  N     . LEU C 2 434  ? 108.086 138.852 151.054 1.00 52.01  ? 449  LEU C N     1 
ATOM   12906 C  CA    . LEU C 2 434  ? 108.977 137.959 151.788 1.00 52.01  ? 449  LEU C CA    1 
ATOM   12907 C  C     . LEU C 2 434  ? 110.184 138.708 152.340 1.00 52.01  ? 449  LEU C C     1 
ATOM   12908 O  O     . LEU C 2 434  ? 110.592 138.478 153.485 1.00 52.01  ? 449  LEU C O     1 
ATOM   12909 C  CB    . LEU C 2 434  ? 109.418 136.806 150.889 1.00 52.01  ? 449  LEU C CB    1 
ATOM   12910 C  CG    . LEU C 2 434  ? 108.330 135.780 150.579 1.00 52.01  ? 449  LEU C CG    1 
ATOM   12911 C  CD1   . LEU C 2 434  ? 108.726 134.914 149.399 1.00 52.01  ? 449  LEU C CD1   1 
ATOM   12912 C  CD2   . LEU C 2 434  ? 108.062 134.926 151.803 1.00 52.01  ? 449  LEU C CD2   1 
ATOM   12913 N  N     . VAL C 2 435  ? 110.766 139.607 151.544 1.00 51.83  ? 450  VAL C N     1 
ATOM   12914 C  CA    . VAL C 2 435  ? 111.895 140.396 152.030 1.00 51.83  ? 450  VAL C CA    1 
ATOM   12915 C  C     . VAL C 2 435  ? 111.470 141.267 153.205 1.00 51.83  ? 450  VAL C C     1 
ATOM   12916 O  O     . VAL C 2 435  ? 112.187 141.375 154.208 1.00 51.83  ? 450  VAL C O     1 
ATOM   12917 C  CB    . VAL C 2 435  ? 112.498 141.234 150.888 1.00 51.83  ? 450  VAL C CB    1 
ATOM   12918 C  CG1   . VAL C 2 435  ? 113.570 142.168 151.425 1.00 51.83  ? 450  VAL C CG1   1 
ATOM   12919 C  CG2   . VAL C 2 435  ? 113.078 140.327 149.819 1.00 51.83  ? 450  VAL C CG2   1 
ATOM   12920 N  N     . LYS C 2 436  ? 110.294 141.893 153.107 1.00 53.53  ? 451  LYS C N     1 
ATOM   12921 C  CA    . LYS C 2 436  ? 109.796 142.717 154.203 1.00 53.53  ? 451  LYS C CA    1 
ATOM   12922 C  C     . LYS C 2 436  ? 109.554 141.887 155.457 1.00 53.53  ? 451  LYS C C     1 
ATOM   12923 O  O     . LYS C 2 436  ? 109.879 142.322 156.567 1.00 53.53  ? 451  LYS C O     1 
ATOM   12924 C  CB    . LYS C 2 436  ? 108.512 143.435 153.783 1.00 53.53  ? 451  LYS C CB    1 
ATOM   12925 C  CG    . LYS C 2 436  ? 108.733 144.689 152.953 1.00 53.53  ? 451  LYS C CG    1 
ATOM   12926 C  CD    . LYS C 2 436  ? 107.417 145.404 152.686 1.00 53.53  ? 451  LYS C CD    1 
ATOM   12927 C  CE    . LYS C 2 436  ? 107.642 146.780 152.082 1.00 53.53  ? 451  LYS C CE    1 
ATOM   12928 N  NZ    . LYS C 2 436  ? 108.341 146.712 150.771 1.00 53.53  ? 451  LYS C NZ    1 
ATOM   12929 N  N     . TYR C 2 437  ? 108.976 140.693 155.303 1.00 45.87  ? 452  TYR C N     1 
ATOM   12930 C  CA    . TYR C 2 437  ? 108.721 139.840 156.458 1.00 45.87  ? 452  TYR C CA    1 
ATOM   12931 C  C     . TYR C 2 437  ? 110.019 139.410 157.126 1.00 45.87  ? 452  TYR C C     1 
ATOM   12932 O  O     . TYR C 2 437  ? 110.121 139.409 158.359 1.00 45.87  ? 452  TYR C O     1 
ATOM   12933 C  CB    . TYR C 2 437  ? 107.905 138.620 156.036 1.00 45.87  ? 452  TYR C CB    1 
ATOM   12934 C  CG    . TYR C 2 437  ? 107.697 137.605 157.136 1.00 45.87  ? 452  TYR C CG    1 
ATOM   12935 C  CD1   . TYR C 2 437  ? 106.661 137.742 158.046 1.00 45.87  ? 452  TYR C CD1   1 
ATOM   12936 C  CD2   . TYR C 2 437  ? 108.533 136.506 157.259 1.00 45.87  ? 452  TYR C CD2   1 
ATOM   12937 C  CE1   . TYR C 2 437  ? 106.465 136.815 159.051 1.00 45.87  ? 452  TYR C CE1   1 
ATOM   12938 C  CE2   . TYR C 2 437  ? 108.346 135.575 158.260 1.00 45.87  ? 452  TYR C CE2   1 
ATOM   12939 C  CZ    . TYR C 2 437  ? 107.311 135.733 159.152 1.00 45.87  ? 452  TYR C CZ    1 
ATOM   12940 O  OH    . TYR C 2 437  ? 107.122 134.806 160.150 1.00 45.87  ? 452  TYR C OH    1 
ATOM   12941 N  N     . LEU C 2 438  ? 111.023 139.035 156.330 1.00 46.56  ? 453  LEU C N     1 
ATOM   12942 C  CA    . LEU C 2 438  ? 112.306 138.643 156.904 1.00 46.56  ? 453  LEU C CA    1 
ATOM   12943 C  C     . LEU C 2 438  ? 112.985 139.817 157.598 1.00 46.56  ? 453  LEU C C     1 
ATOM   12944 O  O     . LEU C 2 438  ? 113.584 139.650 158.667 1.00 46.56  ? 453  LEU C O     1 
ATOM   12945 C  CB    . LEU C 2 438  ? 113.213 138.054 155.824 1.00 46.56  ? 453  LEU C CB    1 
ATOM   12946 C  CG    . LEU C 2 438  ? 112.717 136.758 155.182 1.00 46.56  ? 453  LEU C CG    1 
ATOM   12947 C  CD1   . LEU C 2 438  ? 113.807 136.124 154.334 1.00 46.56  ? 453  LEU C CD1   1 
ATOM   12948 C  CD2   . LEU C 2 438  ? 112.221 135.791 156.243 1.00 46.56  ? 453  LEU C CD2   1 
ATOM   12949 N  N     . ALA C 2 439  ? 112.912 141.011 157.003 1.00 47.22  ? 454  ALA C N     1 
ATOM   12950 C  CA    . ALA C 2 439  ? 113.509 142.184 157.634 1.00 47.22  ? 454  ALA C CA    1 
ATOM   12951 C  C     . ALA C 2 439  ? 112.801 142.535 158.936 1.00 47.22  ? 454  ALA C C     1 
ATOM   12952 O  O     . ALA C 2 439  ? 113.449 142.911 159.919 1.00 47.22  ? 454  ALA C O     1 
ATOM   12953 C  CB    . ALA C 2 439  ? 113.480 143.368 156.669 1.00 47.22  ? 454  ALA C CB    1 
ATOM   12954 N  N     . SER C 2 440  ? 111.471 142.420 158.963 1.00 48.29  ? 455  SER C N     1 
ATOM   12955 C  CA    . SER C 2 440  ? 110.727 142.742 160.175 1.00 48.29  ? 455  SER C CA    1 
ATOM   12956 C  C     . SER C 2 440  ? 110.949 141.703 161.265 1.00 48.29  ? 455  SER C C     1 
ATOM   12957 O  O     . SER C 2 440  ? 110.954 142.048 162.452 1.00 48.29  ? 455  SER C O     1 
ATOM   12958 C  CB    . SER C 2 440  ? 109.237 142.869 159.859 1.00 48.29  ? 455  SER C CB    1 
ATOM   12959 O  OG    . SER C 2 440  ? 108.695 141.627 159.447 1.00 48.29  ? 455  SER C OG    1 
ATOM   12960 N  N     . ALA C 2 441  ? 111.125 140.434 160.888 1.00 45.82  ? 456  ALA C N     1 
ATOM   12961 C  CA    . ALA C 2 441  ? 111.391 139.400 161.884 1.00 45.82  ? 456  ALA C CA    1 
ATOM   12962 C  C     . ALA C 2 441  ? 112.702 139.661 162.612 1.00 45.82  ? 456  ALA C C     1 
ATOM   12963 O  O     . ALA C 2 441  ? 112.796 139.460 163.828 1.00 45.82  ? 456  ALA C O     1 
ATOM   12964 C  CB    . ALA C 2 441  ? 111.409 138.023 161.222 1.00 45.82  ? 456  ALA C CB    1 
ATOM   12965 N  N     . SER C 2 442  ? 113.724 140.104 161.887 1.00 45.53  ? 457  SER C N     1 
ATOM   12966 C  CA    . SER C 2 442  ? 115.009 140.425 162.496 1.00 45.53  ? 457  SER C CA    1 
ATOM   12967 C  C     . SER C 2 442  ? 114.902 141.661 163.383 1.00 45.53  ? 457  SER C C     1 
ATOM   12968 O  O     . SER C 2 442  ? 113.973 142.457 163.248 1.00 45.53  ? 457  SER C O     1 
ATOM   12969 C  CB    . SER C 2 442  ? 116.074 140.643 161.421 1.00 45.53  ? 457  SER C CB    1 
ATOM   12970 O  OG    . SER C 2 442  ? 117.328 140.952 162.005 1.00 45.53  ? 457  SER C OG    1 
ATOM   12971 P  P     . DG  D 3 5    ? 105.359 185.905 126.817 1.00 158.16 ? 5    DG  P P     1 
ATOM   12972 O  OP1   . DG  D 3 5    ? 104.650 184.653 127.161 1.00 158.16 ? 5    DG  P OP1   1 
ATOM   12973 O  OP2   . DG  D 3 5    ? 104.929 187.189 127.414 1.00 158.16 ? 5    DG  P OP2   1 
ATOM   12974 O  "O5'" . DG  D 3 5    ? 106.918 185.720 127.122 1.00 158.16 ? 5    DG  P "O5'" 1 
ATOM   12975 C  "C5'" . DG  D 3 5    ? 107.670 186.805 127.651 1.00 158.16 ? 5    DG  P "C5'" 1 
ATOM   12976 C  "C4'" . DG  D 3 5    ? 109.052 186.348 128.086 1.00 158.16 ? 5    DG  P "C4'" 1 
ATOM   12977 O  "O4'" . DG  D 3 5    ? 108.937 185.449 129.219 1.00 158.16 ? 5    DG  P "O4'" 1 
ATOM   12978 C  "C3'" . DG  D 3 5    ? 109.853 185.594 127.025 1.00 158.16 ? 5    DG  P "C3'" 1 
ATOM   12979 O  "O3'" . DG  D 3 5    ? 111.214 185.996 127.082 1.00 158.16 ? 5    DG  P "O3'" 1 
ATOM   12980 C  "C2'" . DG  D 3 5    ? 109.682 184.132 127.437 1.00 158.16 ? 5    DG  P "C2'" 1 
ATOM   12981 C  "C1'" . DG  D 3 5    ? 109.639 184.255 128.951 1.00 158.16 ? 5    DG  P "C1'" 1 
ATOM   12982 N  N9    . DG  D 3 5    ? 108.942 183.158 129.618 1.00 158.16 ? 5    DG  P N9    1 
ATOM   12983 C  C8    . DG  D 3 5    ? 107.642 182.760 129.421 1.00 158.16 ? 5    DG  P C8    1 
ATOM   12984 N  N7    . DG  D 3 5    ? 107.287 181.754 130.172 1.00 158.16 ? 5    DG  P N7    1 
ATOM   12985 C  C5    . DG  D 3 5    ? 108.424 181.470 130.918 1.00 158.16 ? 5    DG  P C5    1 
ATOM   12986 C  C6    . DG  D 3 5    ? 108.643 180.479 131.904 1.00 158.16 ? 5    DG  P C6    1 
ATOM   12987 O  O6    . DG  D 3 5    ? 107.850 179.627 132.327 1.00 158.16 ? 5    DG  P O6    1 
ATOM   12988 N  N1    . DG  D 3 5    ? 109.939 180.536 132.413 1.00 158.16 ? 5    DG  P N1    1 
ATOM   12989 C  C2    . DG  D 3 5    ? 110.899 181.437 132.019 1.00 158.16 ? 5    DG  P C2    1 
ATOM   12990 N  N2    . DG  D 3 5    ? 112.094 181.343 132.620 1.00 158.16 ? 5    DG  P N2    1 
ATOM   12991 N  N3    . DG  D 3 5    ? 110.705 182.370 131.096 1.00 158.16 ? 5    DG  P N3    1 
ATOM   12992 C  C4    . DG  D 3 5    ? 109.449 182.327 130.591 1.00 158.16 ? 5    DG  P C4    1 
ATOM   12993 P  P     . DC  D 3 6    ? 112.188 185.743 125.831 1.00 154.71 ? 6    DC  P P     1 
ATOM   12994 O  OP1   . DC  D 3 6    ? 112.967 186.982 125.613 1.00 154.71 ? 6    DC  P OP1   1 
ATOM   12995 O  OP2   . DC  D 3 6    ? 111.374 185.185 124.730 1.00 154.71 ? 6    DC  P OP2   1 
ATOM   12996 O  "O5'" . DC  D 3 6    ? 113.176 184.597 126.347 1.00 154.71 ? 6    DC  P "O5'" 1 
ATOM   12997 C  "C5'" . DC  D 3 6    ? 113.904 184.780 127.557 1.00 154.71 ? 6    DC  P "C5'" 1 
ATOM   12998 C  "C4'" . DC  D 3 6    ? 114.619 183.503 127.960 1.00 154.71 ? 6    DC  P "C4'" 1 
ATOM   12999 O  "O4'" . DC  D 3 6    ? 113.666 182.562 128.524 1.00 154.71 ? 6    DC  P "O4'" 1 
ATOM   13000 C  "C3'" . DC  D 3 6    ? 115.316 182.761 126.818 1.00 154.71 ? 6    DC  P "C3'" 1 
ATOM   13001 O  "O3'" . DC  D 3 6    ? 116.563 182.249 127.267 1.00 154.71 ? 6    DC  P "O3'" 1 
ATOM   13002 C  "C2'" . DC  D 3 6    ? 114.335 181.636 126.498 1.00 154.71 ? 6    DC  P "C2'" 1 
ATOM   13003 C  "C1'" . DC  D 3 6    ? 113.813 181.315 127.886 1.00 154.71 ? 6    DC  P "C1'" 1 
ATOM   13004 N  N1    . DC  D 3 6    ? 112.497 180.617 127.897 1.00 154.71 ? 6    DC  P N1    1 
ATOM   13005 C  C2    . DC  D 3 6    ? 112.280 179.580 128.807 1.00 154.71 ? 6    DC  P C2    1 
ATOM   13006 O  O2    . DC  D 3 6    ? 113.191 179.263 129.579 1.00 154.71 ? 6    DC  P O2    1 
ATOM   13007 N  N3    . DC  D 3 6    ? 111.078 178.952 128.813 1.00 154.71 ? 6    DC  P N3    1 
ATOM   13008 C  C4    . DC  D 3 6    ? 110.124 179.329 127.960 1.00 154.71 ? 6    DC  P C4    1 
ATOM   13009 N  N4    . DC  D 3 6    ? 108.954 178.682 128.002 1.00 154.71 ? 6    DC  P N4    1 
ATOM   13010 C  C5    . DC  D 3 6    ? 110.328 180.386 127.024 1.00 154.71 ? 6    DC  P C5    1 
ATOM   13011 C  C6    . DC  D 3 6    ? 111.518 180.997 127.028 1.00 154.71 ? 6    DC  P C6    1 
ATOM   13012 P  P     . DG  D 3 7    ? 117.802 182.128 126.252 1.00 146.66 ? 7    DG  P P     1 
ATOM   13013 O  OP1   . DG  D 3 7    ? 118.597 183.371 126.366 1.00 146.66 ? 7    DG  P OP1   1 
ATOM   13014 O  OP2   . DG  D 3 7    ? 117.265 181.715 124.937 1.00 146.66 ? 7    DG  P OP2   1 
ATOM   13015 O  "O5'" . DG  D 3 7    ? 118.659 180.910 126.836 1.00 146.66 ? 7    DG  P "O5'" 1 
ATOM   13016 C  "C5'" . DG  D 3 7    ? 119.366 181.059 128.062 1.00 146.66 ? 7    DG  P "C5'" 1 
ATOM   13017 C  "C4'" . DG  D 3 7    ? 119.450 179.740 128.815 1.00 146.66 ? 7    DG  P "C4'" 1 
ATOM   13018 O  "O4'" . DG  D 3 7    ? 118.125 179.161 128.941 1.00 146.66 ? 7    DG  P "O4'" 1 
ATOM   13019 C  "C3'" . DG  D 3 7    ? 120.303 178.661 128.161 1.00 146.66 ? 7    DG  P "C3'" 1 
ATOM   13020 O  "O3'" . DG  D 3 7    ? 120.854 177.822 129.176 1.00 146.66 ? 7    DG  P "O3'" 1 
ATOM   13021 C  "C2'" . DG  D 3 7    ? 119.279 177.916 127.306 1.00 146.66 ? 7    DG  P "C2'" 1 
ATOM   13022 C  "C1'" . DG  D 3 7    ? 118.048 177.953 128.204 1.00 146.66 ? 7    DG  P "C1'" 1 
ATOM   13023 N  N9    . DG  D 3 7    ? 116.782 177.955 127.477 1.00 146.66 ? 7    DG  P N9    1 
ATOM   13024 C  C8    . DG  D 3 7    ? 116.423 178.791 126.450 1.00 146.66 ? 7    DG  P C8    1 
ATOM   13025 N  N7    . DG  D 3 7    ? 115.219 178.576 126.001 1.00 146.66 ? 7    DG  P N7    1 
ATOM   13026 C  C5    . DG  D 3 7    ? 114.743 177.537 126.788 1.00 146.66 ? 7    DG  P C5    1 
ATOM   13027 C  C6    . DG  D 3 7    ? 113.493 176.879 126.763 1.00 146.66 ? 7    DG  P C6    1 
ATOM   13028 O  O6    . DG  D 3 7    ? 112.530 177.093 126.016 1.00 146.66 ? 7    DG  P O6    1 
ATOM   13029 N  N1    . DG  D 3 7    ? 113.417 175.879 127.727 1.00 146.66 ? 7    DG  P N1    1 
ATOM   13030 C  C2    . DG  D 3 7    ? 114.423 175.558 128.606 1.00 146.66 ? 7    DG  P C2    1 
ATOM   13031 N  N2    . DG  D 3 7    ? 114.169 174.563 129.466 1.00 146.66 ? 7    DG  P N2    1 
ATOM   13032 N  N3    . DG  D 3 7    ? 115.602 176.168 128.639 1.00 146.66 ? 7    DG  P N3    1 
ATOM   13033 C  C4    . DG  D 3 7    ? 115.690 177.144 127.705 1.00 146.66 ? 7    DG  P C4    1 
ATOM   13034 P  P     . DG  D 3 8    ? 122.016 176.762 128.841 1.00 142.13 ? 8    DG  P P     1 
ATOM   13035 O  OP1   . DG  D 3 8    ? 123.208 177.153 129.626 1.00 142.13 ? 8    DG  P OP1   1 
ATOM   13036 O  OP2   . DG  D 3 8    ? 122.125 176.621 127.373 1.00 142.13 ? 8    DG  P OP2   1 
ATOM   13037 O  "O5'" . DG  D 3 8    ? 121.440 175.390 129.427 1.00 142.13 ? 8    DG  P "O5'" 1 
ATOM   13038 C  "C5'" . DG  D 3 8    ? 120.063 175.086 129.259 1.00 142.13 ? 8    DG  P "C5'" 1 
ATOM   13039 C  "C4'" . DG  D 3 8    ? 119.694 173.779 129.931 1.00 142.13 ? 8    DG  P "C4'" 1 
ATOM   13040 O  "O4'" . DG  D 3 8    ? 118.295 173.514 129.690 1.00 142.13 ? 8    DG  P "O4'" 1 
ATOM   13041 C  "C3'" . DG  D 3 8    ? 120.404 172.559 129.381 1.00 142.13 ? 8    DG  P "C3'" 1 
ATOM   13042 O  "O3'" . DG  D 3 8    ? 120.332 171.489 130.314 1.00 142.13 ? 8    DG  P "O3'" 1 
ATOM   13043 C  "C2'" . DG  D 3 8    ? 119.580 172.263 128.137 1.00 142.13 ? 8    DG  P "C2'" 1 
ATOM   13044 C  "C1'" . DG  D 3 8    ? 118.163 172.633 128.587 1.00 142.13 ? 8    DG  P "C1'" 1 
ATOM   13045 N  N9    . DG  D 3 8    ? 117.382 173.301 127.547 1.00 142.13 ? 8    DG  P N9    1 
ATOM   13046 C  C8    . DG  D 3 8    ? 117.785 174.350 126.756 1.00 142.13 ? 8    DG  P C8    1 
ATOM   13047 N  N7    . DG  D 3 8    ? 116.876 174.739 125.906 1.00 142.13 ? 8    DG  P N7    1 
ATOM   13048 C  C5    . DG  D 3 8    ? 115.799 173.897 126.149 1.00 142.13 ? 8    DG  P C5    1 
ATOM   13049 C  C6    . DG  D 3 8    ? 114.525 173.846 125.534 1.00 142.13 ? 8    DG  P C6    1 
ATOM   13050 O  O6    . DG  D 3 8    ? 114.085 174.560 124.624 1.00 142.13 ? 8    DG  P O6    1 
ATOM   13051 N  N1    . DG  D 3 8    ? 113.729 172.844 126.079 1.00 142.13 ? 8    DG  P N1    1 
ATOM   13052 C  C2    . DG  D 3 8    ? 114.116 171.996 127.090 1.00 142.13 ? 8    DG  P C2    1 
ATOM   13053 N  N2    . DG  D 3 8    ? 113.214 171.089 127.489 1.00 142.13 ? 8    DG  P N2    1 
ATOM   13054 N  N3    . DG  D 3 8    ? 115.307 172.033 127.675 1.00 142.13 ? 8    DG  P N3    1 
ATOM   13055 C  C4    . DG  D 3 8    ? 116.094 173.005 127.156 1.00 142.13 ? 8    DG  P C4    1 
ATOM   13056 P  P     . DT  D 3 9    ? 120.851 170.022 129.910 1.00 138.92 ? 9    DT  P P     1 
ATOM   13057 O  OP1   . DT  D 3 9    ? 121.244 169.332 131.157 1.00 138.92 ? 9    DT  P OP1   1 
ATOM   13058 O  OP2   . DT  D 3 9    ? 121.835 170.166 128.814 1.00 138.92 ? 9    DT  P OP2   1 
ATOM   13059 O  "O5'" . DT  D 3 9    ? 119.551 169.301 129.319 1.00 138.92 ? 9    DT  P "O5'" 1 
ATOM   13060 C  "C5'" . DT  D 3 9    ? 118.382 169.192 130.120 1.00 138.92 ? 9    DT  P "C5'" 1 
ATOM   13061 C  "C4'" . DT  D 3 9    ? 117.316 168.354 129.433 1.00 138.92 ? 9    DT  P "C4'" 1 
ATOM   13062 O  "O4'" . DT  D 3 9    ? 116.632 169.144 128.425 1.00 138.92 ? 9    DT  P "O4'" 1 
ATOM   13063 C  "C3'" . DT  D 3 9    ? 117.816 167.101 128.718 1.00 138.92 ? 9    DT  P "C3'" 1 
ATOM   13064 O  "O3'" . DT  D 3 9    ? 116.886 166.050 128.929 1.00 138.92 ? 9    DT  P "O3'" 1 
ATOM   13065 C  "C2'" . DT  D 3 9    ? 117.845 167.539 127.253 1.00 138.92 ? 9    DT  P "C2'" 1 
ATOM   13066 C  "C1'" . DT  D 3 9    ? 116.622 168.437 127.203 1.00 138.92 ? 9    DT  P "C1'" 1 
ATOM   13067 N  N1    . DT  D 3 9    ? 116.625 169.438 126.094 1.00 138.92 ? 9    DT  P N1    1 
ATOM   13068 C  C2    . DT  D 3 9    ? 115.499 169.581 125.316 1.00 138.92 ? 9    DT  P C2    1 
ATOM   13069 O  O2    . DT  D 3 9    ? 114.493 168.910 125.466 1.00 138.92 ? 9    DT  P O2    1 
ATOM   13070 N  N3    . DT  D 3 9    ? 115.596 170.541 124.343 1.00 138.92 ? 9    DT  P N3    1 
ATOM   13071 C  C4    . DT  D 3 9    ? 116.677 171.358 124.081 1.00 138.92 ? 9    DT  P C4    1 
ATOM   13072 O  O4    . DT  D 3 9    ? 116.669 172.192 123.182 1.00 138.92 ? 9    DT  P O4    1 
ATOM   13073 C  C5    . DT  D 3 9    ? 117.819 171.164 124.935 1.00 138.92 ? 9    DT  P C5    1 
ATOM   13074 C  C7    . DT  D 3 9    ? 119.052 171.994 124.734 1.00 138.92 ? 9    DT  P C7    1 
ATOM   13075 C  C6    . DT  D 3 9    ? 117.740 170.227 125.893 1.00 138.92 ? 9    DT  P C6    1 
ATOM   13076 P  P     . DC  D 3 10   ? 117.243 164.538 128.522 1.00 138.32 ? 10   DC  P P     1 
ATOM   13077 O  OP1   . DC  D 3 10   ? 116.898 163.686 129.680 1.00 138.32 ? 10   DC  P OP1   1 
ATOM   13078 O  OP2   . DC  D 3 10   ? 118.613 164.512 127.966 1.00 138.32 ? 10   DC  P OP2   1 
ATOM   13079 O  "O5'" . DC  D 3 10   ? 116.212 164.212 127.346 1.00 138.32 ? 10   DC  P "O5'" 1 
ATOM   13080 C  "C5'" . DC  D 3 10   ? 114.817 164.174 127.623 1.00 138.32 ? 10   DC  P "C5'" 1 
ATOM   13081 C  "C4'" . DC  D 3 10   ? 114.009 164.014 126.347 1.00 138.32 ? 10   DC  P "C4'" 1 
ATOM   13082 O  "O4'" . DC  D 3 10   ? 114.137 165.210 125.535 1.00 138.32 ? 10   DC  P "O4'" 1 
ATOM   13083 C  "C3'" . DC  D 3 10   ? 114.432 162.852 125.452 1.00 138.32 ? 10   DC  P "C3'" 1 
ATOM   13084 O  "O3'" . DC  D 3 10   ? 113.287 162.266 124.861 1.00 138.32 ? 10   DC  P "O3'" 1 
ATOM   13085 C  "C2'" . DC  D 3 10   ? 115.307 163.535 124.406 1.00 138.32 ? 10   DC  P "C2'" 1 
ATOM   13086 C  "C1'" . DC  D 3 10   ? 114.579 164.858 124.243 1.00 138.32 ? 10   DC  P "C1'" 1 
ATOM   13087 N  N1    . DC  D 3 10   ? 115.435 165.957 123.727 1.00 138.32 ? 10   DC  P N1    1 
ATOM   13088 C  C2    . DC  D 3 10   ? 114.951 166.782 122.709 1.00 138.32 ? 10   DC  P C2    1 
ATOM   13089 O  O2    . DC  D 3 10   ? 113.820 166.573 122.258 1.00 138.32 ? 10   DC  P O2    1 
ATOM   13090 N  N3    . DC  D 3 10   ? 115.737 167.788 122.250 1.00 138.32 ? 10   DC  P N3    1 
ATOM   13091 C  C4    . DC  D 3 10   ? 116.951 167.975 122.771 1.00 138.32 ? 10   DC  P C4    1 
ATOM   13092 N  N4    . DC  D 3 10   ? 117.693 168.977 122.289 1.00 138.32 ? 10   DC  P N4    1 
ATOM   13093 C  C5    . DC  D 3 10   ? 117.459 167.143 123.810 1.00 138.32 ? 10   DC  P C5    1 
ATOM   13094 C  C6    . DC  D 3 10   ? 116.674 166.157 124.254 1.00 138.32 ? 10   DC  P C6    1 
ATOM   13095 P  P     . DG  D 3 11   ? 113.179 160.670 124.720 1.00 139.34 ? 11   DG  P P     1 
ATOM   13096 O  OP1   . DG  D 3 11   ? 112.297 160.184 125.803 1.00 139.34 ? 11   DG  P OP1   1 
ATOM   13097 O  OP2   . DG  D 3 11   ? 114.555 160.141 124.598 1.00 139.34 ? 11   DG  P OP2   1 
ATOM   13098 O  "O5'" . DG  D 3 11   ? 112.443 160.462 123.315 1.00 139.34 ? 11   DG  P "O5'" 1 
ATOM   13099 C  "C5'" . DG  D 3 11   ? 111.166 161.046 123.087 1.00 139.34 ? 11   DG  P "C5'" 1 
ATOM   13100 C  "C4'" . DG  D 3 11   ? 110.948 161.319 121.608 1.00 139.34 ? 11   DG  P "C4'" 1 
ATOM   13101 O  "O4'" . DG  D 3 11   ? 111.742 162.465 121.199 1.00 139.34 ? 11   DG  P "O4'" 1 
ATOM   13102 C  "C3'" . DG  D 3 11   ? 111.340 160.177 120.672 1.00 139.34 ? 11   DG  P "C3'" 1 
ATOM   13103 O  "O3'" . DG  D 3 11   ? 110.403 160.083 119.607 1.00 139.34 ? 11   DG  P "O3'" 1 
ATOM   13104 C  "C2'" . DG  D 3 11   ? 112.719 160.602 120.172 1.00 139.34 ? 11   DG  P "C2'" 1 
ATOM   13105 C  "C1'" . DG  D 3 11   ? 112.564 162.113 120.107 1.00 139.34 ? 11   DG  P "C1'" 1 
ATOM   13106 N  N9    . DG  D 3 11   ? 113.826 162.837 120.233 1.00 139.34 ? 11   DG  P N9    1 
ATOM   13107 C  C8    . DG  D 3 11   ? 114.823 162.604 121.146 1.00 139.34 ? 11   DG  P C8    1 
ATOM   13108 N  N7    . DG  D 3 11   ? 115.837 163.416 121.028 1.00 139.34 ? 11   DG  P N7    1 
ATOM   13109 C  C5    . DG  D 3 11   ? 115.488 164.243 119.970 1.00 139.34 ? 11   DG  P C5    1 
ATOM   13110 C  C6    . DG  D 3 11   ? 116.196 165.318 119.383 1.00 139.34 ? 11   DG  P C6    1 
ATOM   13111 O  O6    . DG  D 3 11   ? 117.308 165.766 119.693 1.00 139.34 ? 11   DG  P O6    1 
ATOM   13112 N  N1    . DG  D 3 11   ? 115.485 165.891 118.332 1.00 139.34 ? 11   DG  P N1    1 
ATOM   13113 C  C2    . DG  D 3 11   ? 114.247 165.476 117.903 1.00 139.34 ? 11   DG  P C2    1 
ATOM   13114 N  N2    . DG  D 3 11   ? 113.714 166.151 116.874 1.00 139.34 ? 11   DG  P N2    1 
ATOM   13115 N  N3    . DG  D 3 11   ? 113.573 164.470 118.446 1.00 139.34 ? 11   DG  P N3    1 
ATOM   13116 C  C4    . DG  D 3 11   ? 114.252 163.902 119.471 1.00 139.34 ? 11   DG  P C4    1 
ATOM   13117 P  P     . DA  D 3 12   ? 110.356 158.770 118.683 1.00 133.06 ? 12   DA  P P     1 
ATOM   13118 O  OP1   . DA  D 3 12   ? 109.068 158.778 117.954 1.00 133.06 ? 12   DA  P OP1   1 
ATOM   13119 O  OP2   . DA  D 3 12   ? 110.706 157.612 119.535 1.00 133.06 ? 12   DA  P OP2   1 
ATOM   13120 O  "O5'" . DA  D 3 12   ? 111.554 158.990 117.645 1.00 133.06 ? 12   DA  P "O5'" 1 
ATOM   13121 C  "C5'" . DA  D 3 12   ? 111.339 158.799 116.252 1.00 133.06 ? 12   DA  P "C5'" 1 
ATOM   13122 C  "C4'" . DA  D 3 12   ? 110.864 160.084 115.595 1.00 133.06 ? 12   DA  P "C4'" 1 
ATOM   13123 O  "O4'" . DA  D 3 12   ? 111.526 161.217 116.213 1.00 133.06 ? 12   DA  P "O4'" 1 
ATOM   13124 C  "C3'" . DA  D 3 12   ? 111.185 160.196 114.115 1.00 133.06 ? 12   DA  P "C3'" 1 
ATOM   13125 O  "O3'" . DA  D 3 12   ? 110.255 161.060 113.475 1.00 133.06 ? 12   DA  P "O3'" 1 
ATOM   13126 C  "C2'" . DA  D 3 12   ? 112.580 160.801 114.139 1.00 133.06 ? 12   DA  P "C2'" 1 
ATOM   13127 C  "C1'" . DA  D 3 12   ? 112.490 161.758 115.326 1.00 133.06 ? 12   DA  P "C1'" 1 
ATOM   13128 N  N9    . DA  D 3 12   ? 113.749 161.898 116.051 1.00 133.06 ? 12   DA  P N9    1 
ATOM   13129 C  C8    . DA  D 3 12   ? 114.174 161.142 117.106 1.00 133.06 ? 12   DA  P C8    1 
ATOM   13130 N  N7    . DA  D 3 12   ? 115.352 161.487 117.566 1.00 133.06 ? 12   DA  P N7    1 
ATOM   13131 C  C5    . DA  D 3 12   ? 115.729 162.543 116.754 1.00 133.06 ? 12   DA  P C5    1 
ATOM   13132 C  C6    . DA  D 3 12   ? 116.882 163.349 116.728 1.00 133.06 ? 12   DA  P C6    1 
ATOM   13133 N  N6    . DA  D 3 12   ? 117.897 163.197 117.581 1.00 133.06 ? 12   DA  P N6    1 
ATOM   13134 N  N1    . DA  D 3 12   ? 116.951 164.319 115.791 1.00 133.06 ? 12   DA  P N1    1 
ATOM   13135 C  C2    . DA  D 3 12   ? 115.926 164.464 114.940 1.00 133.06 ? 12   DA  P C2    1 
ATOM   13136 N  N3    . DA  D 3 12   ? 114.789 163.767 114.869 1.00 133.06 ? 12   DA  P N3    1 
ATOM   13137 C  C4    . DA  D 3 12   ? 114.755 162.812 115.813 1.00 133.06 ? 12   DA  P C4    1 
ATOM   13138 P  P     . DG  D 3 13   ? 109.978 160.918 111.898 1.00 117.82 ? 13   DG  P P     1 
ATOM   13139 O  OP1   . DG  D 3 13   ? 108.757 161.693 111.588 1.00 117.82 ? 13   DG  P OP1   1 
ATOM   13140 O  OP2   . DG  D 3 13   ? 110.037 159.479 111.561 1.00 117.82 ? 13   DG  P OP2   1 
ATOM   13141 O  "O5'" . DG  D 3 13   ? 111.239 161.633 111.215 1.00 117.82 ? 13   DG  P "O5'" 1 
ATOM   13142 C  "C5'" . DG  D 3 13   ? 111.456 163.029 111.401 1.00 117.82 ? 13   DG  P "C5'" 1 
ATOM   13143 C  "C4'" . DG  D 3 13   ? 112.471 163.562 110.401 1.00 117.82 ? 13   DG  P "C4'" 1 
ATOM   13144 O  "O4'" . DG  D 3 13   ? 113.748 163.774 111.060 1.00 117.82 ? 13   DG  P "O4'" 1 
ATOM   13145 C  "C3'" . DG  D 3 13   ? 112.748 162.653 109.209 1.00 117.82 ? 13   DG  P "C3'" 1 
ATOM   13146 O  "O3'" . DG  D 3 13   ? 112.891 163.434 108.026 1.00 117.82 ? 13   DG  P "O3'" 1 
ATOM   13147 C  "C2'" . DG  D 3 13   ? 114.052 161.954 109.594 1.00 117.82 ? 13   DG  P "C2'" 1 
ATOM   13148 C  "C1'" . DG  D 3 13   ? 114.760 163.006 110.439 1.00 117.82 ? 13   DG  P "C1'" 1 
ATOM   13149 N  N9    . DG  D 3 13   ? 115.591 162.427 111.492 1.00 117.82 ? 13   DG  P N9    1 
ATOM   13150 C  C8    . DG  D 3 13   ? 115.249 161.390 112.322 1.00 117.82 ? 13   DG  P C8    1 
ATOM   13151 N  N7    . DG  D 3 13   ? 116.176 161.079 113.179 1.00 117.82 ? 13   DG  P N7    1 
ATOM   13152 C  C5    . DG  D 3 13   ? 117.206 161.965 112.903 1.00 117.82 ? 13   DG  P C5    1 
ATOM   13153 C  C6    . DG  D 3 13   ? 118.471 162.099 113.515 1.00 117.82 ? 13   DG  P C6    1 
ATOM   13154 O  O6    . DG  D 3 13   ? 118.939 161.437 114.448 1.00 117.82 ? 13   DG  P O6    1 
ATOM   13155 N  N1    . DG  D 3 13   ? 119.218 163.121 112.940 1.00 117.82 ? 13   DG  P N1    1 
ATOM   13156 C  C2    . DG  D 3 13   ? 118.795 163.915 111.900 1.00 117.82 ? 13   DG  P C2    1 
ATOM   13157 N  N2    . DG  D 3 13   ? 119.658 164.853 111.476 1.00 117.82 ? 13   DG  P N2    1 
ATOM   13158 N  N3    . DG  D 3 13   ? 117.605 163.801 111.315 1.00 117.82 ? 13   DG  P N3    1 
ATOM   13159 C  C4    . DG  D 3 13   ? 116.865 162.807 111.868 1.00 117.82 ? 13   DG  P C4    1 
ATOM   13160 P  P     . DT  D 3 14   ? 113.362 162.754 106.647 1.00 109.54 ? 14   DT  P P     1 
ATOM   13161 O  OP1   . DT  D 3 14   ? 112.803 163.562 105.541 1.00 109.54 ? 14   DT  P OP1   1 
ATOM   13162 O  OP2   . DT  D 3 14   ? 113.068 161.305 106.710 1.00 109.54 ? 14   DT  P OP2   1 
ATOM   13163 O  "O5'" . DT  D 3 14   ? 114.947 162.950 106.656 1.00 109.54 ? 14   DT  P "O5'" 1 
ATOM   13164 C  "C5'" . DT  D 3 14   ? 115.492 164.235 106.925 1.00 109.54 ? 14   DT  P "C5'" 1 
ATOM   13165 C  "C4'" . DT  D 3 14   ? 116.988 164.255 106.677 1.00 109.54 ? 14   DT  P "C4'" 1 
ATOM   13166 O  "O4'" . DT  D 3 14   ? 117.681 163.675 107.811 1.00 109.54 ? 14   DT  P "O4'" 1 
ATOM   13167 C  "C3'" . DT  D 3 14   ? 117.447 163.486 105.443 1.00 109.54 ? 14   DT  P "C3'" 1 
ATOM   13168 O  "O3'" . DT  D 3 14   ? 118.395 164.259 104.726 1.00 109.54 ? 14   DT  P "O3'" 1 
ATOM   13169 C  "C2'" . DT  D 3 14   ? 118.064 162.207 106.018 1.00 109.54 ? 14   DT  P "C2'" 1 
ATOM   13170 C  "C1'" . DT  D 3 14   ? 118.567 162.667 107.379 1.00 109.54 ? 14   DT  P "C1'" 1 
ATOM   13171 N  N1    . DT  D 3 14   ? 118.568 161.589 108.412 1.00 109.54 ? 14   DT  P N1    1 
ATOM   13172 C  C2    . DT  D 3 14   ? 119.682 161.405 109.199 1.00 109.54 ? 14   DT  P C2    1 
ATOM   13173 O  O2    . DT  D 3 14   ? 120.694 162.075 109.092 1.00 109.54 ? 14   DT  P O2    1 
ATOM   13174 N  N3    . DT  D 3 14   ? 119.571 160.395 110.119 1.00 109.54 ? 14   DT  P N3    1 
ATOM   13175 C  C4    . DT  D 3 14   ? 118.481 159.572 110.330 1.00 109.54 ? 14   DT  P C4    1 
ATOM   13176 O  O4    . DT  D 3 14   ? 118.478 158.691 111.184 1.00 109.54 ? 14   DT  P O4    1 
ATOM   13177 C  C5    . DT  D 3 14   ? 117.346 159.821 109.476 1.00 109.54 ? 14   DT  P C5    1 
ATOM   13178 C  C7    . DT  D 3 14   ? 116.106 158.990 109.613 1.00 109.54 ? 14   DT  P C7    1 
ATOM   13179 C  C6    . DT  D 3 14   ? 117.442 160.806 108.571 1.00 109.54 ? 14   DT  P C6    1 
ATOM   13180 P  P     . DC  D 3 15   ? 118.907 163.787 103.279 1.00 102.93 ? 15   DC  P P     1 
ATOM   13181 O  OP1   . DC  D 3 15   ? 119.005 164.987 102.421 1.00 102.93 ? 15   DC  P OP1   1 
ATOM   13182 O  OP2   . DC  D 3 15   ? 118.080 162.638 102.848 1.00 102.93 ? 15   DC  P OP2   1 
ATOM   13183 O  "O5'" . DC  D 3 15   ? 120.380 163.253 103.571 1.00 102.93 ? 15   DC  P "O5'" 1 
ATOM   13184 C  "C5'" . DC  D 3 15   ? 121.228 163.986 104.442 1.00 102.93 ? 15   DC  P "C5'" 1 
ATOM   13185 C  "C4'" . DC  D 3 15   ? 122.376 163.123 104.918 1.00 102.93 ? 15   DC  P "C4'" 1 
ATOM   13186 O  "O4'" . DC  D 3 15   ? 121.936 162.285 106.004 1.00 102.93 ? 15   DC  P "O4'" 1 
ATOM   13187 C  "C3'" . DC  D 3 15   ? 122.938 162.176 103.861 1.00 102.93 ? 15   DC  P "C3'" 1 
ATOM   13188 O  "O3'" . DC  D 3 15   ? 124.218 162.626 103.450 1.00 102.93 ? 15   DC  P "O3'" 1 
ATOM   13189 C  "C2'" . DC  D 3 15   ? 123.007 160.805 104.557 1.00 102.93 ? 15   DC  P "C2'" 1 
ATOM   13190 C  "C1'" . DC  D 3 15   ? 122.729 161.132 106.019 1.00 102.93 ? 15   DC  P "C1'" 1 
ATOM   13191 N  N1    . DC  D 3 15   ? 121.982 160.062 106.740 1.00 102.93 ? 15   DC  P N1    1 
ATOM   13192 C  C2    . DC  D 3 15   ? 122.607 159.348 107.772 1.00 102.93 ? 15   DC  P C2    1 
ATOM   13193 O  O2    . DC  D 3 15   ? 123.777 159.614 108.068 1.00 102.93 ? 15   DC  P O2    1 
ATOM   13194 N  N3    . DC  D 3 15   ? 121.907 158.380 108.417 1.00 102.93 ? 15   DC  P N3    1 
ATOM   13195 C  C4    . DC  D 3 15   ? 120.644 158.124 108.065 1.00 102.93 ? 15   DC  P C4    1 
ATOM   13196 N  N4    . DC  D 3 15   ? 119.991 157.162 108.726 1.00 102.93 ? 15   DC  P N4    1 
ATOM   13197 C  C5    . DC  D 3 15   ? 119.994 158.842 107.019 1.00 102.93 ? 15   DC  P C5    1 
ATOM   13198 C  C6    . DC  D 3 15   ? 120.693 159.792 106.392 1.00 102.93 ? 15   DC  P C6    1 
ATOM   13199 P  P     . DT  D 3 16   ? 125.008 161.864 102.279 1.00 92.17  ? 16   DT  P P     1 
ATOM   13200 O  OP1   . DT  D 3 16   ? 125.896 162.848 101.623 1.00 92.17  ? 16   DT  P OP1   1 
ATOM   13201 O  OP2   . DT  D 3 16   ? 124.021 161.109 101.478 1.00 92.17  ? 16   DT  P OP2   1 
ATOM   13202 O  "O5'" . DT  D 3 16   ? 125.907 160.808 103.066 1.00 92.17  ? 16   DT  P "O5'" 1 
ATOM   13203 C  "C5'" . DT  D 3 16   ? 126.599 161.208 104.241 1.00 92.17  ? 16   DT  P "C5'" 1 
ATOM   13204 C  "C4'" . DT  D 3 16   ? 127.254 160.013 104.900 1.00 92.17  ? 16   DT  P "C4'" 1 
ATOM   13205 O  "O4'" . DT  D 3 16   ? 126.258 159.259 105.643 1.00 92.17  ? 16   DT  P "O4'" 1 
ATOM   13206 C  "C3'" . DT  D 3 16   ? 127.889 159.028 103.919 1.00 92.17  ? 16   DT  P "C3'" 1 
ATOM   13207 O  "O3'" . DT  D 3 16   ? 129.158 158.615 104.392 1.00 92.17  ? 16   DT  P "O3'" 1 
ATOM   13208 C  "C2'" . DT  D 3 16   ? 126.893 157.874 103.898 1.00 92.17  ? 16   DT  P "C2'" 1 
ATOM   13209 C  "C1'" . DT  D 3 16   ? 126.392 157.897 105.329 1.00 92.17  ? 16   DT  P "C1'" 1 
ATOM   13210 N  N1    . DT  D 3 16   ? 125.076 157.216 105.511 1.00 92.17  ? 16   DT  P N1    1 
ATOM   13211 C  C2    . DT  D 3 16   ? 124.950 156.249 106.480 1.00 92.17  ? 16   DT  P C2    1 
ATOM   13212 O  O2    . DT  D 3 16   ? 125.862 155.920 107.215 1.00 92.17  ? 16   DT  P O2    1 
ATOM   13213 N  N3    . DT  D 3 16   ? 123.707 155.679 106.565 1.00 92.17  ? 16   DT  P N3    1 
ATOM   13214 C  C4    . DT  D 3 16   ? 122.603 155.970 105.788 1.00 92.17  ? 16   DT  P C4    1 
ATOM   13215 O  O4    . DT  D 3 16   ? 121.527 155.403 105.939 1.00 92.17  ? 16   DT  P O4    1 
ATOM   13216 C  C5    . DT  D 3 16   ? 122.805 156.990 104.786 1.00 92.17  ? 16   DT  P C5    1 
ATOM   13217 C  C7    . DT  D 3 16   ? 121.677 157.392 103.883 1.00 92.17  ? 16   DT  P C7    1 
ATOM   13218 C  C6    . DT  D 3 16   ? 124.020 157.554 104.695 1.00 92.17  ? 16   DT  P C6    1 
ATOM   13219 P  P     . DA  D 3 17   ? 130.342 158.318 103.349 1.00 78.93  ? 17   DA  P P     1 
ATOM   13220 O  OP1   . DA  D 3 17   ? 131.393 159.335 103.560 1.00 78.93  ? 17   DA  P OP1   1 
ATOM   13221 O  OP2   . DA  D 3 17   ? 129.724 158.165 102.014 1.00 78.93  ? 17   DA  P OP2   1 
ATOM   13222 O  "O5'" . DA  D 3 17   ? 130.901 156.888 103.797 1.00 78.93  ? 17   DA  P "O5'" 1 
ATOM   13223 C  "C5'" . DA  D 3 17   ? 131.468 156.719 105.090 1.00 78.93  ? 17   DA  P "C5'" 1 
ATOM   13224 C  "C4'" . DA  D 3 17   ? 131.139 155.346 105.638 1.00 78.93  ? 17   DA  P "C4'" 1 
ATOM   13225 O  "O4'" . DA  D 3 17   ? 129.721 155.259 105.854 1.00 78.93  ? 17   DA  P "O4'" 1 
ATOM   13226 C  "C3'" . DA  D 3 17   ? 131.495 154.190 104.707 1.00 78.93  ? 17   DA  P "C3'" 1 
ATOM   13227 O  "O3'" . DA  D 3 17   ? 132.637 153.498 105.194 1.00 78.93  ? 17   DA  P "O3'" 1 
ATOM   13228 C  "C2'" . DA  D 3 17   ? 130.254 153.288 104.701 1.00 78.93  ? 17   DA  P "C2'" 1 
ATOM   13229 C  "C1'" . DA  D 3 17   ? 129.315 153.927 105.718 1.00 78.93  ? 17   DA  P "C1'" 1 
ATOM   13230 N  N9    . DA  D 3 17   ? 127.927 153.920 105.278 1.00 78.93  ? 17   DA  P N9    1 
ATOM   13231 C  C8    . DA  D 3 17   ? 127.372 154.720 104.325 1.00 78.93  ? 17   DA  P C8    1 
ATOM   13232 N  N7    . DA  D 3 17   ? 126.099 154.497 104.119 1.00 78.93  ? 17   DA  P N7    1 
ATOM   13233 C  C5    . DA  D 3 17   ? 125.797 153.469 104.991 1.00 78.93  ? 17   DA  P C5    1 
ATOM   13234 C  C6    . DA  D 3 17   ? 124.604 152.772 105.255 1.00 78.93  ? 17   DA  P C6    1 
ATOM   13235 N  N6    . DA  D 3 17   ? 123.453 153.029 104.629 1.00 78.93  ? 17   DA  P N6    1 
ATOM   13236 N  N1    . DA  D 3 17   ? 124.641 151.799 106.189 1.00 78.93  ? 17   DA  P N1    1 
ATOM   13237 C  C2    . DA  D 3 17   ? 125.800 151.550 106.811 1.00 78.93  ? 17   DA  P C2    1 
ATOM   13238 N  N3    . DA  D 3 17   ? 126.985 152.136 106.645 1.00 78.93  ? 17   DA  P N3    1 
ATOM   13239 C  C4    . DA  D 3 17   ? 126.913 153.098 105.715 1.00 78.93  ? 17   DA  P C4    1 
ATOM   13240 P  P     . DG  D 3 18   ? 133.228 152.244 104.381 1.00 78.68  ? 18   DG  P P     1 
ATOM   13241 O  OP1   . DG  D 3 18   ? 134.639 152.070 104.780 1.00 78.68  ? 18   DG  P OP1   1 
ATOM   13242 O  OP2   . DG  D 3 18   ? 132.887 152.426 102.953 1.00 78.68  ? 18   DG  P OP2   1 
ATOM   13243 O  "O5'" . DG  D 3 18   ? 132.394 151.000 104.933 1.00 78.68  ? 18   DG  P "O5'" 1 
ATOM   13244 C  "C5'" . DG  D 3 18   ? 132.460 150.659 106.304 1.00 78.68  ? 18   DG  P "C5'" 1 
ATOM   13245 C  "C4'" . DG  D 3 18   ? 131.429 149.601 106.639 1.00 78.68  ? 18   DG  P "C4'" 1 
ATOM   13246 O  "O4'" . DG  D 3 18   ? 130.114 150.105 106.329 1.00 78.68  ? 18   DG  P "O4'" 1 
ATOM   13247 C  "C3'" . DG  D 3 18   ? 131.581 148.295 105.858 1.00 78.68  ? 18   DG  P "C3'" 1 
ATOM   13248 O  "O3'" . DG  D 3 18   ? 131.928 147.232 106.737 1.00 78.68  ? 18   DG  P "O3'" 1 
ATOM   13249 C  "C2'" . DG  D 3 18   ? 130.212 148.063 105.201 1.00 78.68  ? 18   DG  P "C2'" 1 
ATOM   13250 C  "C1'" . DG  D 3 18   ? 129.296 149.044 105.918 1.00 78.68  ? 18   DG  P "C1'" 1 
ATOM   13251 N  N9    . DG  D 3 18   ? 128.252 149.588 105.053 1.00 78.68  ? 18   DG  P N9    1 
ATOM   13252 C  C8    . DG  D 3 18   ? 128.378 150.638 104.181 1.00 78.68  ? 18   DG  P C8    1 
ATOM   13253 N  N7    . DG  D 3 18   ? 127.284 150.910 103.530 1.00 78.68  ? 18   DG  P N7    1 
ATOM   13254 C  C5    . DG  D 3 18   ? 126.372 149.976 103.994 1.00 78.68  ? 18   DG  P C5    1 
ATOM   13255 C  C6    . DG  D 3 18   ? 125.016 149.783 103.648 1.00 78.68  ? 18   DG  P C6    1 
ATOM   13256 O  O6    . DG  D 3 18   ? 124.335 150.420 102.834 1.00 78.68  ? 18   DG  P O6    1 
ATOM   13257 N  N1    . DG  D 3 18   ? 124.448 148.727 104.351 1.00 78.68  ? 18   DG  P N1    1 
ATOM   13258 C  C2    . DG  D 3 18   ? 125.108 147.954 105.275 1.00 78.68  ? 18   DG  P C2    1 
ATOM   13259 N  N2    . DG  D 3 18   ? 124.391 146.979 105.852 1.00 78.68  ? 18   DG  P N2    1 
ATOM   13260 N  N3    . DG  D 3 18   ? 126.383 148.124 105.613 1.00 78.68  ? 18   DG  P N3    1 
ATOM   13261 C  C4    . DG  D 3 18   ? 126.950 149.151 104.933 1.00 78.68  ? 18   DG  P C4    1 
ATOM   13262 P  P     . DA  D 3 19   ? 132.401 145.817 106.142 1.00 88.82  ? 19   DA  P P     1 
ATOM   13263 O  OP1   . DA  D 3 19   ? 133.147 145.100 107.196 1.00 88.82  ? 19   DA  P OP1   1 
ATOM   13264 O  OP2   . DA  D 3 19   ? 133.041 146.073 104.834 1.00 88.82  ? 19   DA  P OP2   1 
ATOM   13265 O  "O5'" . DA  D 3 19   ? 131.033 145.040 105.878 1.00 88.82  ? 19   DA  P "O5'" 1 
ATOM   13266 C  "C5'" . DA  D 3 19   ? 130.124 144.838 106.946 1.00 88.82  ? 19   DA  P "C5'" 1 
ATOM   13267 C  "C4'" . DA  D 3 19   ? 128.872 144.135 106.462 1.00 88.82  ? 19   DA  P "C4'" 1 
ATOM   13268 O  "O4'" . DA  D 3 19   ? 128.019 145.078 105.768 1.00 88.82  ? 19   DA  P "O4'" 1 
ATOM   13269 C  "C3'" . DA  D 3 19   ? 129.115 142.975 105.494 1.00 88.82  ? 19   DA  P "C3'" 1 
ATOM   13270 O  "O3'" . DA  D 3 19   ? 128.421 141.823 105.940 1.00 88.82  ? 19   DA  P "O3'" 1 
ATOM   13271 C  "C2'" . DA  D 3 19   ? 128.566 143.485 104.158 1.00 88.82  ? 19   DA  P "C2'" 1 
ATOM   13272 C  "C1'" . DA  D 3 19   ? 127.505 144.476 104.608 1.00 88.82  ? 19   DA  P "C1'" 1 
ATOM   13273 N  N9    . DA  D 3 19   ? 127.236 145.524 103.629 1.00 88.82  ? 19   DA  P N9    1 
ATOM   13274 C  C8    . DA  D 3 19   ? 128.097 146.499 103.211 1.00 88.82  ? 19   DA  P C8    1 
ATOM   13275 N  N7    . DA  D 3 19   ? 127.585 147.313 102.321 1.00 88.82  ? 19   DA  P N7    1 
ATOM   13276 C  C5    . DA  D 3 19   ? 126.298 146.839 102.140 1.00 88.82  ? 19   DA  P C5    1 
ATOM   13277 C  C6    . DA  D 3 19   ? 125.238 147.267 101.320 1.00 88.82  ? 19   DA  P C6    1 
ATOM   13278 N  N6    . DA  D 3 19   ? 125.324 148.318 100.498 1.00 88.82  ? 19   DA  P N6    1 
ATOM   13279 N  N1    . DA  D 3 19   ? 124.082 146.573 101.378 1.00 88.82  ? 19   DA  P N1    1 
ATOM   13280 C  C2    . DA  D 3 19   ? 124.003 145.523 102.205 1.00 88.82  ? 19   DA  P C2    1 
ATOM   13281 N  N3    . DA  D 3 19   ? 124.931 145.025 103.020 1.00 88.82  ? 19   DA  P N3    1 
ATOM   13282 C  C4    . DA  D 3 19   ? 126.065 145.736 102.939 1.00 88.82  ? 19   DA  P C4    1 
ATOM   13283 P  P     . DG  D 3 20   ? 128.784 140.380 105.339 1.00 103.11 ? 20   DG  P P     1 
ATOM   13284 O  OP1   . DG  D 3 20   ? 128.905 139.440 106.475 1.00 103.11 ? 20   DG  P OP1   1 
ATOM   13285 O  OP2   . DG  D 3 20   ? 129.917 140.557 104.404 1.00 103.11 ? 20   DG  P OP2   1 
ATOM   13286 O  "O5'" . DG  D 3 20   ? 127.490 139.990 104.487 1.00 103.11 ? 20   DG  P "O5'" 1 
ATOM   13287 C  "C5'" . DG  D 3 20   ? 127.446 138.759 103.782 1.00 103.11 ? 20   DG  P "C5'" 1 
ATOM   13288 C  "C4'" . DG  D 3 20   ? 126.047 138.493 103.260 1.00 103.11 ? 20   DG  P "C4'" 1 
ATOM   13289 O  "O4'" . DG  D 3 20   ? 125.226 139.673 103.459 1.00 103.11 ? 20   DG  P "O4'" 1 
ATOM   13290 C  "C3'" . DG  D 3 20   ? 125.968 138.186 101.772 1.00 103.11 ? 20   DG  P "C3'" 1 
ATOM   13291 O  "O3'" . DG  D 3 20   ? 126.067 136.782 101.561 1.00 103.11 ? 20   DG  P "O3'" 1 
ATOM   13292 C  "C2'" . DG  D 3 20   ? 124.585 138.712 101.405 1.00 103.11 ? 20   DG  P "C2'" 1 
ATOM   13293 C  "C1'" . DG  D 3 20   ? 124.485 139.952 102.287 1.00 103.11 ? 20   DG  P "C1'" 1 
ATOM   13294 N  N9    . DG  D 3 20   ? 125.036 141.155 101.672 1.00 103.11 ? 20   DG  P N9    1 
ATOM   13295 C  C8    . DG  D 3 20   ? 126.259 141.726 101.927 1.00 103.11 ? 20   DG  P C8    1 
ATOM   13296 N  N7    . DG  D 3 20   ? 126.485 142.804 101.232 1.00 103.11 ? 20   DG  P N7    1 
ATOM   13297 C  C5    . DG  D 3 20   ? 125.338 142.962 100.466 1.00 103.11 ? 20   DG  P C5    1 
ATOM   13298 C  C6    . DG  D 3 20   ? 125.008 143.958 99.519  1.00 103.11 ? 20   DG  P C6    1 
ATOM   13299 O  O6    . DG  D 3 20   ? 125.686 144.930 99.162  1.00 103.11 ? 20   DG  P O6    1 
ATOM   13300 N  N1    . DG  D 3 20   ? 123.745 143.749 98.969  1.00 103.11 ? 20   DG  P N1    1 
ATOM   13301 C  C2    . DG  D 3 20   ? 122.908 142.706 99.295  1.00 103.11 ? 20   DG  P C2    1 
ATOM   13302 N  N2    . DG  D 3 20   ? 121.727 142.667 98.659  1.00 103.11 ? 20   DG  P N2    1 
ATOM   13303 N  N3    . DG  D 3 20   ? 123.208 141.764 100.181 1.00 103.11 ? 20   DG  P N3    1 
ATOM   13304 C  C4    . DG  D 3 20   ? 124.434 141.956 100.725 1.00 103.11 ? 20   DG  P C4    1 
ATOM   13305 P  P     . DG  D 3 21   ? 126.657 136.212 100.179 1.00 112.85 ? 21   DG  P P     1 
ATOM   13306 O  OP1   . DG  D 3 21   ? 125.961 134.940 99.883  1.00 112.85 ? 21   DG  P OP1   1 
ATOM   13307 O  OP2   . DG  D 3 21   ? 128.133 136.235 100.274 1.00 112.85 ? 21   DG  P OP2   1 
ATOM   13308 O  "O5'" . DG  D 3 21   ? 126.216 137.306 99.100  1.00 112.85 ? 21   DG  P "O5'" 1 
ATOM   13309 C  "C5'" . DG  D 3 21   ? 125.978 136.927 97.753  1.00 112.85 ? 21   DG  P "C5'" 1 
ATOM   13310 C  "C4'" . DG  D 3 21   ? 124.600 137.380 97.307  1.00 112.85 ? 21   DG  P "C4'" 1 
ATOM   13311 O  "O4'" . DG  D 3 21   ? 124.210 138.553 98.066  1.00 112.85 ? 21   DG  P "O4'" 1 
ATOM   13312 C  "C3'" . DG  D 3 21   ? 124.499 137.774 95.839  1.00 112.85 ? 21   DG  P "C3'" 1 
ATOM   13313 O  "O3'" . DG  D 3 21   ? 124.058 136.660 95.074  1.00 112.85 ? 21   DG  P "O3'" 1 
ATOM   13314 C  "C2'" . DG  D 3 21   ? 123.452 138.882 95.857  1.00 112.85 ? 21   DG  P "C2'" 1 
ATOM   13315 C  "C1'" . DG  D 3 21   ? 123.719 139.553 97.198  1.00 112.85 ? 21   DG  P "C1'" 1 
ATOM   13316 N  N9    . DG  D 3 21   ? 124.700 140.634 97.141  1.00 112.85 ? 21   DG  P N9    1 
ATOM   13317 C  C8    . DG  D 3 21   ? 125.873 140.719 97.851  1.00 112.85 ? 21   DG  P C8    1 
ATOM   13318 N  N7    . DG  D 3 21   ? 126.550 141.806 97.608  1.00 112.85 ? 21   DG  P N7    1 
ATOM   13319 C  C5    . DG  D 3 21   ? 125.777 142.487 96.678  1.00 112.85 ? 21   DG  P C5    1 
ATOM   13320 C  C6    . DG  D 3 21   ? 126.004 143.730 96.044  1.00 112.85 ? 21   DG  P C6    1 
ATOM   13321 O  O6    . DG  D 3 21   ? 126.966 144.498 96.185  1.00 112.85 ? 21   DG  P O6    1 
ATOM   13322 N  N1    . DG  D 3 21   ? 124.973 144.059 95.169  1.00 112.85 ? 21   DG  P N1    1 
ATOM   13323 C  C2    . DG  D 3 21   ? 123.862 143.283 94.937  1.00 112.85 ? 21   DG  P C2    1 
ATOM   13324 N  N2    . DG  D 3 21   ? 122.969 143.763 94.060  1.00 112.85 ? 21   DG  P N2    1 
ATOM   13325 N  N3    . DG  D 3 21   ? 123.637 142.115 95.526  1.00 112.85 ? 21   DG  P N3    1 
ATOM   13326 C  C4    . DG  D 3 21   ? 124.633 141.781 96.381  1.00 112.85 ? 21   DG  P C4    1 
ATOM   13327 P  P     . DA  D 3 22   ? 124.744 136.317 93.662  1.00 107.92 ? 22   DA  P P     1 
ATOM   13328 O  OP1   . DA  D 3 22   ? 124.219 135.009 93.212  1.00 107.92 ? 22   DA  P OP1   1 
ATOM   13329 O  OP2   . DA  D 3 22   ? 126.202 136.513 93.813  1.00 107.92 ? 22   DA  P OP2   1 
ATOM   13330 O  "O5'" . DA  D 3 22   ? 124.195 137.453 92.682  1.00 107.92 ? 22   DA  P "O5'" 1 
ATOM   13331 C  "C5'" . DA  D 3 22   ? 122.795 137.663 92.544  1.00 107.92 ? 22   DA  P "C5'" 1 
ATOM   13332 C  "C4'" . DA  D 3 22   ? 122.518 139.069 92.055  1.00 107.92 ? 22   DA  P "C4'" 1 
ATOM   13333 O  "O4'" . DA  D 3 22   ? 123.257 139.993 92.871  1.00 107.92 ? 22   DA  P "O4'" 1 
ATOM   13334 C  "C3'" . DA  D 3 22   ? 122.972 139.341 90.631  1.00 107.92 ? 22   DA  P "C3'" 1 
ATOM   13335 O  "O3'" . DA  D 3 22   ? 121.901 139.090 89.732  1.00 107.92 ? 22   DA  P "O3'" 1 
ATOM   13336 C  "C2'" . DA  D 3 22   ? 123.349 140.826 90.642  1.00 107.92 ? 22   DA  P "C2'" 1 
ATOM   13337 C  "C1'" . DA  D 3 22   ? 123.585 141.140 92.122  1.00 107.92 ? 22   DA  P "C1'" 1 
ATOM   13338 N  N9    . DA  D 3 22   ? 124.957 141.520 92.442  1.00 107.92 ? 22   DA  P N9    1 
ATOM   13339 C  C8    . DA  D 3 22   ? 125.855 140.815 93.195  1.00 107.92 ? 22   DA  P C8    1 
ATOM   13340 N  N7    . DA  D 3 22   ? 127.017 141.410 93.327  1.00 107.92 ? 22   DA  P N7    1 
ATOM   13341 C  C5    . DA  D 3 22   ? 126.870 142.588 92.614  1.00 107.92 ? 22   DA  P C5    1 
ATOM   13342 C  C6    . DA  D 3 22   ? 127.745 143.664 92.364  1.00 107.92 ? 22   DA  P C6    1 
ATOM   13343 N  N6    . DA  D 3 22   ? 128.997 143.721 92.830  1.00 107.92 ? 22   DA  P N6    1 
ATOM   13344 N  N1    . DA  D 3 22   ? 127.281 144.684 91.613  1.00 107.92 ? 22   DA  P N1    1 
ATOM   13345 C  C2    . DA  D 3 22   ? 126.030 144.624 91.146  1.00 107.92 ? 22   DA  P C2    1 
ATOM   13346 N  N3    . DA  D 3 22   ? 125.116 143.671 91.315  1.00 107.92 ? 22   DA  P N3    1 
ATOM   13347 C  C4    . DA  D 3 22   ? 125.605 142.672 92.064  1.00 107.92 ? 22   DA  P C4    1 
ATOM   13348 P  P     . DG  D 3 23   ? 121.951 137.819 88.751  1.00 80.47  ? 23   DG  P P     1 
ATOM   13349 O  OP1   . DG  D 3 23   ? 123.358 137.636 88.333  1.00 80.47  ? 23   DG  P OP1   1 
ATOM   13350 O  OP2   . DG  D 3 23   ? 120.893 137.993 87.731  1.00 80.47  ? 23   DG  P OP2   1 
ATOM   13351 O  "O5'" . DG  D 3 23   ? 121.560 136.588 89.694  1.00 80.47  ? 23   DG  P "O5'" 1 
ATOM   13352 C  "C5'" . DG  D 3 23   ? 120.254 136.504 90.249  1.00 80.47  ? 23   DG  P "C5'" 1 
ATOM   13353 C  "C4'" . DG  D 3 23   ? 119.792 135.061 90.317  1.00 80.47  ? 23   DG  P "C4'" 1 
ATOM   13354 O  "O4'" . DG  D 3 23   ? 120.655 134.316 91.216  1.00 80.47  ? 23   DG  P "O4'" 1 
ATOM   13355 C  "C3'" . DG  D 3 23   ? 118.378 134.865 90.848  1.00 80.47  ? 23   DG  P "C3'" 1 
ATOM   13356 O  "O3'" . DG  D 3 23   ? 117.789 133.735 90.230  1.00 80.47  ? 23   DG  P "O3'" 1 
ATOM   13357 C  "C2'" . DG  D 3 23   ? 118.619 134.624 92.332  1.00 80.47  ? 23   DG  P "C2'" 1 
ATOM   13358 C  "C1'" . DG  D 3 23   ? 119.893 133.796 92.287  1.00 80.47  ? 23   DG  P "C1'" 1 
ATOM   13359 N  N9    . DG  D 3 23   ? 120.693 133.884 93.505  1.00 80.47  ? 23   DG  P N9    1 
ATOM   13360 C  C8    . DG  D 3 23   ? 121.236 135.018 94.055  1.00 80.47  ? 23   DG  P C8    1 
ATOM   13361 N  N7    . DG  D 3 23   ? 121.911 134.795 95.147  1.00 80.47  ? 23   DG  P N7    1 
ATOM   13362 C  C5    . DG  D 3 23   ? 121.813 133.423 95.333  1.00 80.47  ? 23   DG  P C5    1 
ATOM   13363 C  C6    . DG  D 3 23   ? 122.347 132.603 96.355  1.00 80.47  ? 23   DG  P C6    1 
ATOM   13364 O  O6    . DG  D 3 23   ? 123.035 132.941 97.329  1.00 80.47  ? 23   DG  P O6    1 
ATOM   13365 N  N1    . DG  D 3 23   ? 122.011 131.264 96.170  1.00 80.47  ? 23   DG  P N1    1 
ATOM   13366 C  C2    . DG  D 3 23   ? 121.255 130.780 95.128  1.00 80.47  ? 23   DG  P C2    1 
ATOM   13367 N  N2    . DG  D 3 23   ? 121.035 129.456 95.118  1.00 80.47  ? 23   DG  P N2    1 
ATOM   13368 N  N3    . DG  D 3 23   ? 120.748 131.539 94.163  1.00 80.47  ? 23   DG  P N3    1 
ATOM   13369 C  C4    . DG  D 3 23   ? 121.067 132.846 94.330  1.00 80.47  ? 23   DG  P C4    1 
ATOM   13370 P  P     . DC  D 3 24   ? 116.259 133.783 89.746  1.00 74.73  ? 24   DC  P P     1 
ATOM   13371 O  OP1   . DC  D 3 24   ? 116.236 133.459 88.304  1.00 74.73  ? 24   DC  P OP1   1 
ATOM   13372 O  OP2   . DC  D 3 24   ? 115.675 135.057 90.220  1.00 74.73  ? 24   DC  P OP2   1 
ATOM   13373 O  "O5'" . DC  D 3 24   ? 115.564 132.600 90.566  1.00 74.73  ? 24   DC  P "O5'" 1 
ATOM   13374 C  "C5'" . DC  D 3 24   ? 115.157 132.821 91.906  1.00 74.73  ? 24   DC  P "C5'" 1 
ATOM   13375 C  "C4'" . DC  D 3 24   ? 115.314 131.564 92.740  1.00 74.73  ? 24   DC  P "C4'" 1 
ATOM   13376 O  "O4'" . DC  D 3 24   ? 116.674 131.474 93.217  1.00 74.73  ? 24   DC  P "O4'" 1 
ATOM   13377 C  "C3'" . DC  D 3 24   ? 114.457 131.528 93.991  1.00 74.73  ? 24   DC  P "C3'" 1 
ATOM   13378 O  "O3'" . DC  D 3 24   ? 113.180 130.977 93.685  1.00 74.73  ? 24   DC  P "O3'" 1 
ATOM   13379 C  "C2'" . DC  D 3 24   ? 115.250 130.606 94.917  1.00 74.73  ? 24   DC  P "C2'" 1 
ATOM   13380 C  "C1'" . DC  D 3 24   ? 116.700 130.839 94.482  1.00 74.73  ? 24   DC  P "C1'" 1 
ATOM   13381 N  N1    . DC  D 3 24   ? 117.489 131.687 95.426  1.00 74.73  ? 24   DC  P N1    1 
ATOM   13382 C  C2    . DC  D 3 24   ? 118.136 131.093 96.516  1.00 74.73  ? 24   DC  P C2    1 
ATOM   13383 O  O2    . DC  D 3 24   ? 118.035 129.873 96.686  1.00 74.73  ? 24   DC  P O2    1 
ATOM   13384 N  N3    . DC  D 3 24   ? 118.854 131.876 97.359  1.00 74.73  ? 24   DC  P N3    1 
ATOM   13385 C  C4    . DC  D 3 24   ? 118.939 133.189 97.142  1.00 74.73  ? 24   DC  P C4    1 
ATOM   13386 N  N4    . DC  D 3 24   ? 119.659 133.919 98.000  1.00 74.73  ? 24   DC  P N4    1 
ATOM   13387 C  C5    . DC  D 3 24   ? 118.290 133.811 96.036  1.00 74.73  ? 24   DC  P C5    1 
ATOM   13388 C  C6    . DC  D 3 24   ? 117.584 133.029 95.212  1.00 74.73  ? 24   DC  P C6    1 
ATOM   13389 P  P     . DT  D 3 25   ? 111.926 131.939 93.389  1.00 69.45  ? 25   DT  P P     1 
ATOM   13390 O  OP1   . DT  D 3 25   ? 111.282 131.457 92.147  1.00 69.45  ? 25   DT  P OP1   1 
ATOM   13391 O  OP2   . DT  D 3 25   ? 112.392 133.339 93.478  1.00 69.45  ? 25   DT  P OP2   1 
ATOM   13392 O  "O5'" . DT  D 3 25   ? 110.936 131.676 94.617  1.00 69.45  ? 25   DT  P "O5'" 1 
ATOM   13393 C  "C5'" . DT  D 3 25   ? 111.170 132.307 95.871  1.00 69.45  ? 25   DT  P "C5'" 1 
ATOM   13394 C  "C4'" . DT  D 3 25   ? 112.096 131.472 96.737  1.00 69.45  ? 25   DT  P "C4'" 1 
ATOM   13395 O  "O4'" . DT  D 3 25   ? 113.303 132.211 96.987  1.00 69.45  ? 25   DT  P "O4'" 1 
ATOM   13396 C  "C3'" . DT  D 3 25   ? 111.546 131.135 98.114  1.00 69.45  ? 25   DT  P "C3'" 1 
ATOM   13397 O  "O3'" . DT  D 3 25   ? 110.921 129.860 98.084  1.00 69.45  ? 25   DT  P "O3'" 1 
ATOM   13398 C  "C2'" . DT  D 3 25   ? 112.782 131.132 99.030  1.00 69.45  ? 25   DT  P "C2'" 1 
ATOM   13399 C  "C1'" . DT  D 3 25   ? 113.899 131.732 98.165  1.00 69.45  ? 25   DT  P "C1'" 1 
ATOM   13400 N  N1    . DT  D 3 25   ? 114.620 132.867 98.816  1.00 69.45  ? 25   DT  P N1    1 
ATOM   13401 C  C2    . DT  D 3 25   ? 115.393 132.631 99.932  1.00 69.45  ? 25   DT  P C2    1 
ATOM   13402 O  O2    . DT  D 3 25   ? 115.526 131.530 100.437 1.00 69.45  ? 25   DT  P O2    1 
ATOM   13403 N  N3    . DT  D 3 25   ? 116.012 133.741 100.442 1.00 69.45  ? 25   DT  P N3    1 
ATOM   13404 C  C4    . DT  D 3 25   ? 115.940 135.034 99.960  1.00 69.45  ? 25   DT  P C4    1 
ATOM   13405 O  O4    . DT  D 3 25   ? 116.535 135.966 100.491 1.00 69.45  ? 25   DT  P O4    1 
ATOM   13406 C  C5    . DT  D 3 25   ? 115.116 135.211 98.788  1.00 69.45  ? 25   DT  P C5    1 
ATOM   13407 C  C7    . DT  D 3 25   ? 114.962 136.571 98.173  1.00 69.45  ? 25   DT  P C7    1 
ATOM   13408 C  C6    . DT  D 3 25   ? 114.505 134.132 98.279  1.00 69.45  ? 25   DT  P C6    1 
ATOM   13409 P  P     . DG  E 4 17   ? 141.446 145.362 87.575  1.00 102.22 ? 17   DG  T P     1 
ATOM   13410 O  OP1   . DG  E 4 17   ? 141.093 144.179 86.759  1.00 102.22 ? 17   DG  T OP1   1 
ATOM   13411 O  OP2   . DG  E 4 17   ? 142.845 145.576 88.005  1.00 102.22 ? 17   DG  T OP2   1 
ATOM   13412 O  "O5'" . DG  E 4 17   ? 140.967 146.679 86.806  1.00 102.22 ? 17   DG  T "O5'" 1 
ATOM   13413 C  "C5'" . DG  E 4 17   ? 140.916 147.926 87.490  1.00 102.22 ? 17   DG  T "C5'" 1 
ATOM   13414 C  "C4'" . DG  E 4 17   ? 140.388 149.013 86.575  1.00 102.22 ? 17   DG  T "C4'" 1 
ATOM   13415 O  "O4'" . DG  E 4 17   ? 139.658 148.402 85.493  1.00 102.22 ? 17   DG  T "O4'" 1 
ATOM   13416 C  "C3'" . DG  E 4 17   ? 139.378 149.941 87.211  1.00 102.22 ? 17   DG  T "C3'" 1 
ATOM   13417 O  "O3'" . DG  E 4 17   ? 139.242 151.115 86.420  1.00 102.22 ? 17   DG  T "O3'" 1 
ATOM   13418 C  "C2'" . DG  E 4 17   ? 138.114 149.088 87.161  1.00 102.22 ? 17   DG  T "C2'" 1 
ATOM   13419 C  "C1'" . DG  E 4 17   ? 138.284 148.337 85.835  1.00 102.22 ? 17   DG  T "C1'" 1 
ATOM   13420 N  N9    . DG  E 4 17   ? 137.903 146.932 85.910  1.00 102.22 ? 17   DG  T N9    1 
ATOM   13421 C  C8    . DG  E 4 17   ? 137.876 146.139 87.032  1.00 102.22 ? 17   DG  T C8    1 
ATOM   13422 N  N7    . DG  E 4 17   ? 137.498 144.915 86.793  1.00 102.22 ? 17   DG  T N7    1 
ATOM   13423 C  C5    . DG  E 4 17   ? 137.263 144.894 85.424  1.00 102.22 ? 17   DG  T C5    1 
ATOM   13424 C  C6    . DG  E 4 17   ? 136.832 143.836 84.590  1.00 102.22 ? 17   DG  T C6    1 
ATOM   13425 O  O6    . DG  E 4 17   ? 136.563 142.669 84.907  1.00 102.22 ? 17   DG  T O6    1 
ATOM   13426 N  N1    . DG  E 4 17   ? 136.720 144.242 83.261  1.00 102.22 ? 17   DG  T N1    1 
ATOM   13427 C  C2    . DG  E 4 17   ? 136.993 145.508 82.799  1.00 102.22 ? 17   DG  T C2    1 
ATOM   13428 N  N2    . DG  E 4 17   ? 136.827 145.712 81.484  1.00 102.22 ? 17   DG  T N2    1 
ATOM   13429 N  N3    . DG  E 4 17   ? 137.397 146.507 83.571  1.00 102.22 ? 17   DG  T N3    1 
ATOM   13430 C  C4    . DG  E 4 17   ? 137.510 146.128 84.867  1.00 102.22 ? 17   DG  T C4    1 
ATOM   13431 P  P     . DC  E 4 18   ? 138.520 152.419 87.018  1.00 124.23 ? 18   DC  T P     1 
ATOM   13432 O  OP1   . DC  E 4 18   ? 138.874 153.565 86.152  1.00 124.23 ? 18   DC  T OP1   1 
ATOM   13433 O  OP2   . DC  E 4 18   ? 138.817 152.472 88.467  1.00 124.23 ? 18   DC  T OP2   1 
ATOM   13434 O  "O5'" . DC  E 4 18   ? 136.960 152.107 86.849  1.00 124.23 ? 18   DC  T "O5'" 1 
ATOM   13435 C  "C5'" . DC  E 4 18   ? 136.139 151.950 87.999  1.00 124.23 ? 18   DC  T "C5'" 1 
ATOM   13436 C  "C4'" . DC  E 4 18   ? 134.695 151.711 87.602  1.00 124.23 ? 18   DC  T "C4'" 1 
ATOM   13437 O  "O4'" . DC  E 4 18   ? 134.572 150.406 86.986  1.00 124.23 ? 18   DC  T "O4'" 1 
ATOM   13438 C  "C3'" . DC  E 4 18   ? 133.713 151.695 88.757  1.00 124.23 ? 18   DC  T "C3'" 1 
ATOM   13439 O  "O3'" . DC  E 4 18   ? 133.274 153.021 89.032  1.00 124.23 ? 18   DC  T "O3'" 1 
ATOM   13440 C  "C2'" . DC  E 4 18   ? 132.583 150.831 88.208  1.00 124.23 ? 18   DC  T "C2'" 1 
ATOM   13441 C  "C1'" . DC  E 4 18   ? 133.343 149.807 87.362  1.00 124.23 ? 18   DC  T "C1'" 1 
ATOM   13442 N  N1    . DC  E 4 18   ? 133.636 148.528 88.078  1.00 124.23 ? 18   DC  T N1    1 
ATOM   13443 C  C2    . DC  E 4 18   ? 132.613 147.594 88.280  1.00 124.23 ? 18   DC  T C2    1 
ATOM   13444 O  O2    . DC  E 4 18   ? 131.475 147.846 87.866  1.00 124.23 ? 18   DC  T O2    1 
ATOM   13445 N  N3    . DC  E 4 18   ? 132.899 146.439 88.928  1.00 124.23 ? 18   DC  T N3    1 
ATOM   13446 C  C4    . DC  E 4 18   ? 134.139 146.203 89.359  1.00 124.23 ? 18   DC  T C4    1 
ATOM   13447 N  N4    . DC  E 4 18   ? 134.371 145.049 89.993  1.00 124.23 ? 18   DC  T N4    1 
ATOM   13448 C  C5    . DC  E 4 18   ? 135.194 147.140 89.160  1.00 124.23 ? 18   DC  T C5    1 
ATOM   13449 C  C6    . DC  E 4 18   ? 134.902 148.276 88.521  1.00 124.23 ? 18   DC  T C6    1 
ATOM   13450 P  P     . DT  E 4 19   ? 132.227 153.299 90.218  1.00 129.08 ? 19   DT  T P     1 
ATOM   13451 O  OP1   . DT  E 4 19   ? 132.384 154.711 90.632  1.00 129.08 ? 19   DT  T OP1   1 
ATOM   13452 O  OP2   . DT  E 4 19   ? 132.380 152.218 91.216  1.00 129.08 ? 19   DT  T OP2   1 
ATOM   13453 O  "O5'" . DT  E 4 19   ? 130.802 153.120 89.515  1.00 129.08 ? 19   DT  T "O5'" 1 
ATOM   13454 C  "C5'" . DT  E 4 19   ? 129.629 153.032 90.304  1.00 129.08 ? 19   DT  T "C5'" 1 
ATOM   13455 C  "C4'" . DT  E 4 19   ? 128.510 152.369 89.524  1.00 129.08 ? 19   DT  T "C4'" 1 
ATOM   13456 O  "O4'" . DT  E 4 19   ? 129.016 151.171 88.883  1.00 129.08 ? 19   DT  T "O4'" 1 
ATOM   13457 C  "C3'" . DT  E 4 19   ? 127.328 151.920 90.370  1.00 129.08 ? 19   DT  T "C3'" 1 
ATOM   13458 O  "O3'" . DT  E 4 19   ? 126.353 152.956 90.415  1.00 129.08 ? 19   DT  T "O3'" 1 
ATOM   13459 C  "C2'" . DT  E 4 19   ? 126.812 150.702 89.612  1.00 129.08 ? 19   DT  T "C2'" 1 
ATOM   13460 C  "C1'" . DT  E 4 19   ? 128.096 150.108 89.031  1.00 129.08 ? 19   DT  T "C1'" 1 
ATOM   13461 N  N1    . DT  E 4 19   ? 128.728 149.048 89.883  1.00 129.08 ? 19   DT  T N1    1 
ATOM   13462 C  C2    . DT  E 4 19   ? 128.052 147.872 90.119  1.00 129.08 ? 19   DT  T C2    1 
ATOM   13463 O  O2    . DT  E 4 19   ? 126.941 147.635 89.679  1.00 129.08 ? 19   DT  T O2    1 
ATOM   13464 N  N3    . DT  E 4 19   ? 128.726 146.972 90.900  1.00 129.08 ? 19   DT  T N3    1 
ATOM   13465 C  C4    . DT  E 4 19   ? 129.983 147.121 91.453  1.00 129.08 ? 19   DT  T C4    1 
ATOM   13466 O  O4    . DT  E 4 19   ? 130.502 146.251 92.144  1.00 129.08 ? 19   DT  T O4    1 
ATOM   13467 C  C5    . DT  E 4 19   ? 130.640 148.373 91.163  1.00 129.08 ? 19   DT  T C5    1 
ATOM   13468 C  C7    . DT  E 4 19   ? 132.008 148.650 91.710  1.00 129.08 ? 19   DT  T C7    1 
ATOM   13469 C  C6    . DT  E 4 19   ? 129.990 149.263 90.399  1.00 129.08 ? 19   DT  T C6    1 
ATOM   13470 P  P     . DC  E 4 20   ? 125.457 153.171 91.731  1.00 132.48 ? 20   DC  T P     1 
ATOM   13471 O  OP1   . DC  E 4 20   ? 124.761 154.469 91.590  1.00 132.48 ? 20   DC  T OP1   1 
ATOM   13472 O  OP2   . DC  E 4 20   ? 126.319 152.924 92.908  1.00 132.48 ? 20   DC  T OP2   1 
ATOM   13473 O  "O5'" . DC  E 4 20   ? 124.376 151.997 91.652  1.00 132.48 ? 20   DC  T "O5'" 1 
ATOM   13474 C  "C5'" . DC  E 4 20   ? 123.506 151.909 90.531  1.00 132.48 ? 20   DC  T "C5'" 1 
ATOM   13475 C  "C4'" . DC  E 4 20   ? 122.754 150.592 90.536  1.00 132.48 ? 20   DC  T "C4'" 1 
ATOM   13476 O  "O4'" . DC  E 4 20   ? 123.691 149.499 90.374  1.00 132.48 ? 20   DC  T "O4'" 1 
ATOM   13477 C  "C3'" . DC  E 4 20   ? 122.020 150.282 91.825  1.00 132.48 ? 20   DC  T "C3'" 1 
ATOM   13478 O  "O3'" . DC  E 4 20   ? 120.738 150.890 91.815  1.00 132.48 ? 20   DC  T "O3'" 1 
ATOM   13479 C  "C2'" . DC  E 4 20   ? 121.920 148.763 91.769  1.00 132.48 ? 20   DC  T "C2'" 1 
ATOM   13480 C  "C1'" . DC  E 4 20   ? 123.262 148.383 91.139  1.00 132.48 ? 20   DC  T "C1'" 1 
ATOM   13481 N  N1    . DC  E 4 20   ? 124.319 148.055 92.141  1.00 132.48 ? 20   DC  T N1    1 
ATOM   13482 C  C2    . DC  E 4 20   ? 124.299 146.814 92.788  1.00 132.48 ? 20   DC  T C2    1 
ATOM   13483 O  O2    . DC  E 4 20   ? 123.403 146.007 92.512  1.00 132.48 ? 20   DC  T O2    1 
ATOM   13484 N  N3    . DC  E 4 20   ? 125.268 146.530 93.694  1.00 132.48 ? 20   DC  T N3    1 
ATOM   13485 C  C4    . DC  E 4 20   ? 126.218 147.429 93.959  1.00 132.48 ? 20   DC  T C4    1 
ATOM   13486 N  N4    . DC  E 4 20   ? 127.152 147.109 94.860  1.00 132.48 ? 20   DC  T N4    1 
ATOM   13487 C  C5    . DC  E 4 20   ? 126.253 148.699 93.311  1.00 132.48 ? 20   DC  T C5    1 
ATOM   13488 C  C6    . DC  E 4 20   ? 125.295 148.966 92.418  1.00 132.48 ? 20   DC  T C6    1 
ATOM   13489 P  P     . DC  E 4 21   ? 120.088 151.421 93.185  1.00 127.60 ? 21   DC  T P     1 
ATOM   13490 O  OP1   . DC  E 4 21   ? 118.924 152.264 92.836  1.00 127.60 ? 21   DC  T OP1   1 
ATOM   13491 O  OP2   . DC  E 4 21   ? 121.183 151.981 94.007  1.00 127.60 ? 21   DC  T OP2   1 
ATOM   13492 O  "O5'" . DC  E 4 21   ? 119.569 150.090 93.904  1.00 127.60 ? 21   DC  T "O5'" 1 
ATOM   13493 C  "C5'" . DC  E 4 21   ? 118.607 149.262 93.260  1.00 127.60 ? 21   DC  T "C5'" 1 
ATOM   13494 C  "C4'" . DC  E 4 21   ? 118.333 148.017 94.083  1.00 127.60 ? 21   DC  T "C4'" 1 
ATOM   13495 O  "O4'" . DC  E 4 21   ? 119.500 147.170 94.072  1.00 127.60 ? 21   DC  T "O4'" 1 
ATOM   13496 C  "C3'" . DC  E 4 21   ? 118.042 148.278 95.548  1.00 127.60 ? 21   DC  T "C3'" 1 
ATOM   13497 O  "O3'" . DC  E 4 21   ? 116.644 148.484 95.727  1.00 127.60 ? 21   DC  T "O3'" 1 
ATOM   13498 C  "C2'" . DC  E 4 21   ? 118.508 146.991 96.232  1.00 127.60 ? 21   DC  T "C2'" 1 
ATOM   13499 C  "C1'" . DC  E 4 21   ? 119.591 146.454 95.289  1.00 127.60 ? 21   DC  T "C1'" 1 
ATOM   13500 N  N1    . DC  E 4 21   ? 120.984 146.593 95.811  1.00 127.60 ? 21   DC  T N1    1 
ATOM   13501 C  C2    . DC  E 4 21   ? 121.456 145.710 96.794  1.00 127.60 ? 21   DC  T C2    1 
ATOM   13502 O  O2    . DC  E 4 21   ? 120.703 144.833 97.232  1.00 127.60 ? 21   DC  T O2    1 
ATOM   13503 N  N3    . DC  E 4 21   ? 122.730 145.850 97.241  1.00 127.60 ? 21   DC  T N3    1 
ATOM   13504 C  C4    . DC  E 4 21   ? 123.512 146.810 96.742  1.00 127.60 ? 21   DC  T C4    1 
ATOM   13505 N  N4    . DC  E 4 21   ? 124.760 146.912 97.212  1.00 127.60 ? 21   DC  T N4    1 
ATOM   13506 C  C5    . DC  E 4 21   ? 123.049 147.711 95.740  1.00 127.60 ? 21   DC  T C5    1 
ATOM   13507 C  C6    . DC  E 4 21   ? 121.795 147.565 95.306  1.00 127.60 ? 21   DC  T C6    1 
ATOM   13508 P  P     . DT  E 4 22   ? 116.103 149.395 96.934  1.00 124.14 ? 22   DT  T P     1 
ATOM   13509 O  OP1   . DT  E 4 22   ? 114.675 149.685 96.676  1.00 124.14 ? 22   DT  T OP1   1 
ATOM   13510 O  OP2   . DT  E 4 22   ? 117.059 150.509 97.117  1.00 124.14 ? 22   DT  T OP2   1 
ATOM   13511 O  "O5'" . DT  E 4 22   ? 116.203 148.435 98.209  1.00 124.14 ? 22   DT  T "O5'" 1 
ATOM   13512 C  "C5'" . DT  E 4 22   ? 115.551 147.170 98.198  1.00 124.14 ? 22   DT  T "C5'" 1 
ATOM   13513 C  "C4'" . DT  E 4 22   ? 116.104 146.269 99.287  1.00 124.14 ? 22   DT  T "C4'" 1 
ATOM   13514 O  "O4'" . DT  E 4 22   ? 117.554 146.246 99.206  1.00 124.14 ? 22   DT  T "O4'" 1 
ATOM   13515 C  "C3'" . DT  E 4 22   ? 115.762 146.703 100.711 1.00 124.14 ? 22   DT  T "C3'" 1 
ATOM   13516 O  "O3'" . DT  E 4 22   ? 115.435 145.572 101.503 1.00 124.14 ? 22   DT  T "O3'" 1 
ATOM   13517 C  "C2'" . DT  E 4 22   ? 117.045 147.374 101.192 1.00 124.14 ? 22   DT  T "C2'" 1 
ATOM   13518 C  "C1'" . DT  E 4 22   ? 118.109 146.570 100.461 1.00 124.14 ? 22   DT  T "C1'" 1 
ATOM   13519 N  N1    . DT  E 4 22   ? 119.371 147.332 100.241 1.00 124.14 ? 22   DT  T N1    1 
ATOM   13520 C  C2    . DT  E 4 22   ? 120.492 147.002 100.967 1.00 124.14 ? 22   DT  T C2    1 
ATOM   13521 O  O2    . DT  E 4 22   ? 120.515 146.103 101.787 1.00 124.14 ? 22   DT  T O2    1 
ATOM   13522 N  N3    . DT  E 4 22   ? 121.596 147.765 100.694 1.00 124.14 ? 22   DT  T N3    1 
ATOM   13523 C  C4    . DT  E 4 22   ? 121.687 148.808 99.789  1.00 124.14 ? 22   DT  T C4    1 
ATOM   13524 O  O4    . DT  E 4 22   ? 122.725 149.436 99.614  1.00 124.14 ? 22   DT  T O4    1 
ATOM   13525 C  C5    . DT  E 4 22   ? 120.474 149.104 99.065  1.00 124.14 ? 22   DT  T C5    1 
ATOM   13526 C  C7    . DT  E 4 22   ? 120.451 150.213 98.056  1.00 124.14 ? 22   DT  T C7    1 
ATOM   13527 C  C6    . DT  E 4 22   ? 119.388 148.362 99.325  1.00 124.14 ? 22   DT  T C6    1 
ATOM   13528 P  P     . DC  E 4 23   ? 114.562 145.754 102.840 1.00 117.47 ? 23   DC  T P     1 
ATOM   13529 O  OP1   . DC  E 4 23   ? 113.651 144.593 102.946 1.00 117.47 ? 23   DC  T OP1   1 
ATOM   13530 O  OP2   . DC  E 4 23   ? 114.008 147.125 102.825 1.00 117.47 ? 23   DC  T OP2   1 
ATOM   13531 O  "O5'" . DC  E 4 23   ? 115.643 145.677 104.016 1.00 117.47 ? 23   DC  T "O5'" 1 
ATOM   13532 C  "C5'" . DC  E 4 23   ? 116.380 144.480 104.222 1.00 117.47 ? 23   DC  T "C5'" 1 
ATOM   13533 C  "C4'" . DC  E 4 23   ? 117.424 144.668 105.308 1.00 117.47 ? 23   DC  T "C4'" 1 
ATOM   13534 O  "O4'" . DC  E 4 23   ? 118.567 145.379 104.768 1.00 117.47 ? 23   DC  T "O4'" 1 
ATOM   13535 C  "C3'" . DC  E 4 23   ? 116.955 145.465 106.528 1.00 117.47 ? 23   DC  T "C3'" 1 
ATOM   13536 O  "O3'" . DC  E 4 23   ? 117.268 144.751 107.719 1.00 117.47 ? 23   DC  T "O3'" 1 
ATOM   13537 C  "C2'" . DC  E 4 23   ? 117.733 146.780 106.429 1.00 117.47 ? 23   DC  T "C2'" 1 
ATOM   13538 C  "C1'" . DC  E 4 23   ? 118.988 146.352 105.689 1.00 117.47 ? 23   DC  T "C1'" 1 
ATOM   13539 N  N1    . DC  E 4 23   ? 119.635 147.461 104.937 1.00 117.47 ? 23   DC  T N1    1 
ATOM   13540 C  C2    . DC  E 4 23   ? 120.974 147.783 105.185 1.00 117.47 ? 23   DC  T C2    1 
ATOM   13541 O  O2    . DC  E 4 23   ? 121.608 147.135 106.025 1.00 117.47 ? 23   DC  T O2    1 
ATOM   13542 N  N3    . DC  E 4 23   ? 121.545 148.796 104.488 1.00 117.47 ? 23   DC  T N3    1 
ATOM   13543 C  C4    . DC  E 4 23   ? 120.829 149.471 103.588 1.00 117.47 ? 23   DC  T C4    1 
ATOM   13544 N  N4    . DC  E 4 23   ? 121.432 150.463 102.926 1.00 117.47 ? 23   DC  T N4    1 
ATOM   13545 C  C5    . DC  E 4 23   ? 119.464 149.159 103.325 1.00 117.47 ? 23   DC  T C5    1 
ATOM   13546 C  C6    . DC  E 4 23   ? 118.914 148.157 104.015 1.00 117.47 ? 23   DC  T C6    1 
ATOM   13547 P  P     . DT  E 4 24   ? 117.047 145.425 109.161 1.00 104.89 ? 24   DT  T P     1 
ATOM   13548 O  OP1   . DT  E 4 24   ? 116.816 144.328 110.126 1.00 104.89 ? 24   DT  T OP1   1 
ATOM   13549 O  OP2   . DT  E 4 24   ? 116.043 146.506 109.033 1.00 104.89 ? 24   DT  T OP2   1 
ATOM   13550 O  "O5'" . DT  E 4 24   ? 118.462 146.092 109.485 1.00 104.89 ? 24   DT  T "O5'" 1 
ATOM   13551 C  "C5'" . DT  E 4 24   ? 119.647 145.315 109.371 1.00 104.89 ? 24   DT  T "C5'" 1 
ATOM   13552 C  "C4'" . DT  E 4 24   ? 120.800 145.979 110.098 1.00 104.89 ? 24   DT  T "C4'" 1 
ATOM   13553 O  "O4'" . DT  E 4 24   ? 121.442 146.942 109.223 1.00 104.89 ? 24   DT  T "O4'" 1 
ATOM   13554 C  "C3'" . DT  E 4 24   ? 120.409 146.744 111.360 1.00 104.89 ? 24   DT  T "C3'" 1 
ATOM   13555 O  "O3'" . DT  E 4 24   ? 121.380 146.527 112.367 1.00 104.89 ? 24   DT  T "O3'" 1 
ATOM   13556 C  "C2'" . DT  E 4 24   ? 120.401 148.197 110.892 1.00 104.89 ? 24   DT  T "C2'" 1 
ATOM   13557 C  "C1'" . DT  E 4 24   ? 121.530 148.187 109.876 1.00 104.89 ? 24   DT  T "C1'" 1 
ATOM   13558 N  N1    . DT  E 4 24   ? 121.418 149.258 108.851 1.00 104.89 ? 24   DT  T N1    1 
ATOM   13559 C  C2    . DT  E 4 24   ? 122.515 150.038 108.568 1.00 104.89 ? 24   DT  T C2    1 
ATOM   13560 O  O2    . DT  E 4 24   ? 123.591 149.902 109.120 1.00 104.89 ? 24   DT  T O2    1 
ATOM   13561 N  N3    . DT  E 4 24   ? 122.309 150.989 107.607 1.00 104.89 ? 24   DT  T N3    1 
ATOM   13562 C  C4    . DT  E 4 24   ? 121.138 151.235 106.917 1.00 104.89 ? 24   DT  T C4    1 
ATOM   13563 O  O4    . DT  E 4 24   ? 121.050 152.116 106.070 1.00 104.89 ? 24   DT  T O4    1 
ATOM   13564 C  C5    . DT  E 4 24   ? 120.026 150.381 107.262 1.00 104.89 ? 24   DT  T C5    1 
ATOM   13565 C  C7    . DT  E 4 24   ? 118.703 150.552 106.578 1.00 104.89 ? 24   DT  T C7    1 
ATOM   13566 C  C6    . DT  E 4 24   ? 120.219 149.444 108.201 1.00 104.89 ? 24   DT  T C6    1 
ATOM   13567 P  P     . DA  E 4 25   ? 121.065 146.898 113.898 1.00 95.10  ? 25   DA  T P     1 
ATOM   13568 O  OP1   . DA  E 4 25   ? 121.318 145.688 114.709 1.00 95.10  ? 25   DA  T OP1   1 
ATOM   13569 O  OP2   . DA  E 4 25   ? 119.742 147.560 113.953 1.00 95.10  ? 25   DA  T OP2   1 
ATOM   13570 O  "O5'" . DA  E 4 25   ? 122.177 147.986 114.250 1.00 95.10  ? 25   DA  T "O5'" 1 
ATOM   13571 C  "C5'" . DA  E 4 25   ? 123.534 147.721 113.941 1.00 95.10  ? 25   DA  T "C5'" 1 
ATOM   13572 C  "C4'" . DA  E 4 25   ? 124.311 149.011 113.786 1.00 95.10  ? 25   DA  T "C4'" 1 
ATOM   13573 O  "O4'" . DA  E 4 25   ? 123.906 149.683 112.567 1.00 95.10  ? 25   DA  T "O4'" 1 
ATOM   13574 C  "C3'" . DA  E 4 25   ? 124.111 150.023 114.917 1.00 95.10  ? 25   DA  T "C3'" 1 
ATOM   13575 O  "O3'" . DA  E 4 25   ? 125.367 150.510 115.348 1.00 95.10  ? 25   DA  T "O3'" 1 
ATOM   13576 C  "C2'" . DA  E 4 25   ? 123.276 151.127 114.267 1.00 95.10  ? 25   DA  T "C2'" 1 
ATOM   13577 C  "C1'" . DA  E 4 25   ? 123.761 151.054 112.833 1.00 95.10  ? 25   DA  T "C1'" 1 
ATOM   13578 N  N9    . DA  E 4 25   ? 122.830 151.625 111.865 1.00 95.10  ? 25   DA  T N9    1 
ATOM   13579 C  C8    . DA  E 4 25   ? 121.529 151.262 111.655 1.00 95.10  ? 25   DA  T C8    1 
ATOM   13580 N  N7    . DA  E 4 25   ? 120.934 151.951 110.710 1.00 95.10  ? 25   DA  T N7    1 
ATOM   13581 C  C5    . DA  E 4 25   ? 121.913 152.827 110.271 1.00 95.10  ? 25   DA  T C5    1 
ATOM   13582 C  C6    . DA  E 4 25   ? 121.917 153.828 109.279 1.00 95.10  ? 25   DA  T C6    1 
ATOM   13583 N  N6    . DA  E 4 25   ? 120.853 154.119 108.525 1.00 95.10  ? 25   DA  T N6    1 
ATOM   13584 N  N1    . DA  E 4 25   ? 123.063 154.519 109.091 1.00 95.10  ? 25   DA  T N1    1 
ATOM   13585 C  C2    . DA  E 4 25   ? 124.124 154.223 109.853 1.00 95.10  ? 25   DA  T C2    1 
ATOM   13586 N  N3    . DA  E 4 25   ? 124.238 153.306 110.812 1.00 95.10  ? 25   DA  T N3    1 
ATOM   13587 C  C4    . DA  E 4 25   ? 123.088 152.637 110.972 1.00 95.10  ? 25   DA  T C4    1 
ATOM   13588 P  P     . DG  E 4 26   ? 125.542 151.077 116.838 1.00 74.25  ? 26   DG  T P     1 
ATOM   13589 O  OP1   . DG  E 4 26   ? 126.523 150.214 117.528 1.00 74.25  ? 26   DG  T OP1   1 
ATOM   13590 O  OP2   . DG  E 4 26   ? 124.190 151.259 117.411 1.00 74.25  ? 26   DG  T OP2   1 
ATOM   13591 O  "O5'" . DG  E 4 26   ? 126.196 152.516 116.614 1.00 74.25  ? 26   DG  T "O5'" 1 
ATOM   13592 C  "C5'" . DG  E 4 26   ? 127.452 152.613 115.977 1.00 74.25  ? 26   DG  T "C5'" 1 
ATOM   13593 C  "C4'" . DG  E 4 26   ? 127.668 153.998 115.398 1.00 74.25  ? 26   DG  T "C4'" 1 
ATOM   13594 O  "O4'" . DG  E 4 26   ? 126.735 154.227 114.313 1.00 74.25  ? 26   DG  T "O4'" 1 
ATOM   13595 C  "C3'" . DG  E 4 26   ? 127.479 155.154 116.379 1.00 74.25  ? 26   DG  T "C3'" 1 
ATOM   13596 O  "O3'" . DG  E 4 26   ? 128.544 156.074 116.229 1.00 74.25  ? 26   DG  T "O3'" 1 
ATOM   13597 C  "C2'" . DG  E 4 26   ? 126.143 155.765 115.955 1.00 74.25  ? 26   DG  T "C2'" 1 
ATOM   13598 C  "C1'" . DG  E 4 26   ? 126.152 155.498 114.460 1.00 74.25  ? 26   DG  T "C1'" 1 
ATOM   13599 N  N9    . DG  E 4 26   ? 124.823 155.458 113.857 1.00 74.25  ? 26   DG  T N9    1 
ATOM   13600 C  C8    . DG  E 4 26   ? 123.791 154.614 114.187 1.00 74.25  ? 26   DG  T C8    1 
ATOM   13601 N  N7    . DG  E 4 26   ? 122.720 154.796 113.467 1.00 74.25  ? 26   DG  T N7    1 
ATOM   13602 C  C5    . DG  E 4 26   ? 123.064 155.823 112.599 1.00 74.25  ? 26   DG  T C5    1 
ATOM   13603 C  C6    . DG  E 4 26   ? 122.303 156.448 111.583 1.00 74.25  ? 26   DG  T C6    1 
ATOM   13604 O  O6    . DG  E 4 26   ? 121.137 156.210 111.241 1.00 74.25  ? 26   DG  T O6    1 
ATOM   13605 N  N1    . DG  E 4 26   ? 123.028 157.444 110.934 1.00 74.25  ? 26   DG  T N1    1 
ATOM   13606 C  C2    . DG  E 4 26   ? 124.326 157.791 111.231 1.00 74.25  ? 26   DG  T C2    1 
ATOM   13607 N  N2    . DG  E 4 26   ? 124.861 158.780 110.498 1.00 74.25  ? 26   DG  T N2    1 
ATOM   13608 N  N3    . DG  E 4 26   ? 125.051 157.212 112.183 1.00 74.25  ? 26   DG  T N3    1 
ATOM   13609 C  C4    . DG  E 4 26   ? 124.357 156.240 112.823 1.00 74.25  ? 26   DG  T C4    1 
ATOM   13610 P  P     . DA  E 4 27   ? 128.732 157.276 117.274 1.00 69.51  ? 27   DA  T P     1 
ATOM   13611 O  OP1   . DA  E 4 27   ? 130.176 157.399 117.569 1.00 69.51  ? 27   DA  T OP1   1 
ATOM   13612 O  OP2   . DA  E 4 27   ? 127.772 157.063 118.377 1.00 69.51  ? 27   DA  T OP2   1 
ATOM   13613 O  "O5'" . DA  E 4 27   ? 128.278 158.563 116.447 1.00 69.51  ? 27   DA  T "O5'" 1 
ATOM   13614 C  "C5'" . DA  E 4 27   ? 128.992 158.933 115.279 1.00 69.51  ? 27   DA  T "C5'" 1 
ATOM   13615 C  "C4'" . DA  E 4 27   ? 128.389 160.170 114.642 1.00 69.51  ? 27   DA  T "C4'" 1 
ATOM   13616 O  "O4'" . DA  E 4 27   ? 127.142 159.824 113.989 1.00 69.51  ? 27   DA  T "O4'" 1 
ATOM   13617 C  "C3'" . DA  E 4 27   ? 128.055 161.300 115.612 1.00 69.51  ? 27   DA  T "C3'" 1 
ATOM   13618 O  "O3'" . DA  E 4 27   ? 128.357 162.540 115.010 1.00 69.51  ? 27   DA  T "O3'" 1 
ATOM   13619 C  "C2'" . DA  E 4 27   ? 126.555 161.135 115.812 1.00 69.51  ? 27   DA  T "C2'" 1 
ATOM   13620 C  "C1'" . DA  E 4 27   ? 126.137 160.706 114.421 1.00 69.51  ? 27   DA  T "C1'" 1 
ATOM   13621 N  N9    . DA  E 4 27   ? 124.861 160.007 114.377 1.00 69.51  ? 27   DA  T N9    1 
ATOM   13622 C  C8    . DA  E 4 27   ? 124.444 158.995 115.192 1.00 69.51  ? 27   DA  T C8    1 
ATOM   13623 N  N7    . DA  E 4 27   ? 123.241 158.552 114.910 1.00 69.51  ? 27   DA  T N7    1 
ATOM   13624 C  C5    . DA  E 4 27   ? 122.848 159.326 113.832 1.00 69.51  ? 27   DA  T C5    1 
ATOM   13625 C  C6    . DA  E 4 27   ? 121.670 159.353 113.063 1.00 69.51  ? 27   DA  T C6    1 
ATOM   13626 N  N6    . DA  E 4 27   ? 120.632 158.540 113.278 1.00 69.51  ? 27   DA  T N6    1 
ATOM   13627 N  N1    . DA  E 4 27   ? 121.601 160.251 112.056 1.00 69.51  ? 27   DA  T N1    1 
ATOM   13628 C  C2    . DA  E 4 27   ? 122.642 161.062 111.844 1.00 69.51  ? 27   DA  T C2    1 
ATOM   13629 N  N3    . DA  E 4 27   ? 123.797 161.130 112.501 1.00 69.51  ? 27   DA  T N3    1 
ATOM   13630 C  C4    . DA  E 4 27   ? 123.836 160.226 113.491 1.00 69.51  ? 27   DA  T C4    1 
ATOM   13631 P  P     . DC  E 4 28   ? 128.678 163.825 115.917 1.00 87.41  ? 28   DC  T P     1 
ATOM   13632 O  OP1   . DC  E 4 28   ? 130.136 164.068 115.850 1.00 87.41  ? 28   DC  T OP1   1 
ATOM   13633 O  OP2   . DC  E 4 28   ? 128.028 163.623 117.228 1.00 87.41  ? 28   DC  T OP2   1 
ATOM   13634 O  "O5'" . DC  E 4 28   ? 127.922 165.014 115.164 1.00 87.41  ? 28   DC  T "O5'" 1 
ATOM   13635 C  "C5'" . DC  E 4 28   ? 128.217 165.287 113.802 1.00 87.41  ? 28   DC  T "C5'" 1 
ATOM   13636 C  "C4'" . DC  E 4 28   ? 127.090 166.063 113.148 1.00 87.41  ? 28   DC  T "C4'" 1 
ATOM   13637 O  "O4'" . DC  E 4 28   ? 125.954 165.187 112.926 1.00 87.41  ? 28   DC  T "O4'" 1 
ATOM   13638 C  "C3'" . DC  E 4 28   ? 126.573 167.249 113.957 1.00 87.41  ? 28   DC  T "C3'" 1 
ATOM   13639 O  "O3'" . DC  E 4 28   ? 126.421 168.376 113.109 1.00 87.41  ? 28   DC  T "O3'" 1 
ATOM   13640 C  "C2'" . DC  E 4 28   ? 125.232 166.759 114.506 1.00 87.41  ? 28   DC  T "C2'" 1 
ATOM   13641 C  "C1'" . DC  E 4 28   ? 124.780 165.770 113.443 1.00 87.41  ? 28   DC  T "C1'" 1 
ATOM   13642 N  N1    . DC  E 4 28   ? 123.931 164.680 113.988 1.00 87.41  ? 28   DC  T N1    1 
ATOM   13643 C  C2    . DC  E 4 28   ? 122.699 164.382 113.392 1.00 87.41  ? 28   DC  T C2    1 
ATOM   13644 O  O2    . DC  E 4 28   ? 122.326 165.036 112.412 1.00 87.41  ? 28   DC  T O2    1 
ATOM   13645 N  N3    . DC  E 4 28   ? 121.948 163.379 113.910 1.00 87.41  ? 28   DC  T N3    1 
ATOM   13646 C  C4    . DC  E 4 28   ? 122.385 162.699 114.969 1.00 87.41  ? 28   DC  T C4    1 
ATOM   13647 N  N4    . DC  E 4 28   ? 121.617 161.717 115.447 1.00 87.41  ? 28   DC  T N4    1 
ATOM   13648 C  C5    . DC  E 4 28   ? 123.633 162.990 115.585 1.00 87.41  ? 28   DC  T C5    1 
ATOM   13649 C  C6    . DC  E 4 28   ? 124.367 163.974 115.066 1.00 87.41  ? 28   DC  T C6    1 
ATOM   13650 P  P     . DT  E 4 29   ? 125.743 169.725 113.656 1.00 111.40 ? 29   DT  T P     1 
ATOM   13651 O  OP1   . DT  E 4 29   ? 126.296 170.842 112.860 1.00 111.40 ? 29   DT  T OP1   1 
ATOM   13652 O  OP2   . DT  E 4 29   ? 125.861 169.752 115.131 1.00 111.40 ? 29   DT  T OP2   1 
ATOM   13653 O  "O5'" . DT  E 4 29   ? 124.203 169.544 113.278 1.00 111.40 ? 29   DT  T "O5'" 1 
ATOM   13654 C  "C5'" . DT  E 4 29   ? 123.845 169.090 111.978 1.00 111.40 ? 29   DT  T "C5'" 1 
ATOM   13655 C  "C4'" . DT  E 4 29   ? 122.362 169.283 111.734 1.00 111.40 ? 29   DT  T "C4'" 1 
ATOM   13656 O  "O4'" . DT  E 4 29   ? 121.635 168.103 112.169 1.00 111.40 ? 29   DT  T "O4'" 1 
ATOM   13657 C  "C3'" . DT  E 4 29   ? 121.746 170.465 112.473 1.00 111.40 ? 29   DT  T "C3'" 1 
ATOM   13658 O  "O3'" . DT  E 4 29   ? 120.823 171.133 111.633 1.00 111.40 ? 29   DT  T "O3'" 1 
ATOM   13659 C  "C2'" . DT  E 4 29   ? 121.055 169.810 113.667 1.00 111.40 ? 29   DT  T "C2'" 1 
ATOM   13660 C  "C1'" . DT  E 4 29   ? 120.630 168.467 113.091 1.00 111.40 ? 29   DT  T "C1'" 1 
ATOM   13661 N  N1    . DT  E 4 29   ? 120.533 167.391 114.117 1.00 111.40 ? 29   DT  T N1    1 
ATOM   13662 C  C2    . DT  E 4 29   ? 119.447 166.543 114.117 1.00 111.40 ? 29   DT  T C2    1 
ATOM   13663 O  O2    . DT  E 4 29   ? 118.539 166.620 113.311 1.00 111.40 ? 29   DT  T O2    1 
ATOM   13664 N  N3    . DT  E 4 29   ? 119.468 165.589 115.102 1.00 111.40 ? 29   DT  T N3    1 
ATOM   13665 C  C4    . DT  E 4 29   ? 120.443 165.409 116.064 1.00 111.40 ? 29   DT  T C4    1 
ATOM   13666 O  O4    . DT  E 4 29   ? 120.378 164.525 116.909 1.00 111.40 ? 29   DT  T O4    1 
ATOM   13667 C  C5    . DT  E 4 29   ? 121.549 166.333 116.005 1.00 111.40 ? 29   DT  T C5    1 
ATOM   13668 C  C7    . DT  E 4 29   ? 122.665 166.236 117.000 1.00 111.40 ? 29   DT  T C7    1 
ATOM   13669 C  C6    . DT  E 4 29   ? 121.540 167.266 115.046 1.00 111.40 ? 29   DT  T C6    1 
ATOM   13670 P  P     . DC  E 4 30   ? 120.399 172.650 111.948 1.00 129.77 ? 30   DC  T P     1 
ATOM   13671 O  OP1   . DC  E 4 30   ? 120.554 173.423 110.697 1.00 129.77 ? 30   DC  T OP1   1 
ATOM   13672 O  OP2   . DC  E 4 30   ? 121.119 173.078 113.168 1.00 129.77 ? 30   DC  T OP2   1 
ATOM   13673 O  "O5'" . DC  E 4 30   ? 118.845 172.536 112.305 1.00 129.77 ? 30   DC  T "O5'" 1 
ATOM   13674 C  "C5'" . DC  E 4 30   ? 117.954 171.925 111.381 1.00 129.77 ? 30   DC  T "C5'" 1 
ATOM   13675 C  "C4'" . DC  E 4 30   ? 116.714 171.408 112.086 1.00 129.77 ? 30   DC  T "C4'" 1 
ATOM   13676 O  "O4'" . DC  E 4 30   ? 116.997 170.136 112.694 1.00 129.77 ? 30   DC  T "O4'" 1 
ATOM   13677 C  "C3'" . DC  E 4 30   ? 116.223 172.274 113.229 1.00 129.77 ? 30   DC  T "C3'" 1 
ATOM   13678 O  "O3'" . DC  E 4 30   ? 115.359 173.287 112.726 1.00 129.77 ? 30   DC  T "O3'" 1 
ATOM   13679 C  "C2'" . DC  E 4 30   ? 115.465 171.277 114.113 1.00 129.77 ? 30   DC  T "C2'" 1 
ATOM   13680 C  "C1'" . DC  E 4 30   ? 116.098 169.923 113.764 1.00 129.77 ? 30   DC  T "C1'" 1 
ATOM   13681 N  N1    . DC  E 4 30   ? 116.846 169.292 114.893 1.00 129.77 ? 30   DC  T N1    1 
ATOM   13682 C  C2    . DC  E 4 30   ? 116.313 168.170 115.539 1.00 129.77 ? 30   DC  T C2    1 
ATOM   13683 O  O2    . DC  E 4 30   ? 115.222 167.724 115.172 1.00 129.77 ? 30   DC  T O2    1 
ATOM   13684 N  N3    . DC  E 4 30   ? 117.010 167.605 116.556 1.00 129.77 ? 30   DC  T N3    1 
ATOM   13685 C  C4    . DC  E 4 30   ? 118.186 168.116 116.923 1.00 129.77 ? 30   DC  T C4    1 
ATOM   13686 N  N4    . DC  E 4 30   ? 118.839 167.526 117.929 1.00 129.77 ? 30   DC  T N4    1 
ATOM   13687 C  C5    . DC  E 4 30   ? 118.746 169.256 116.275 1.00 129.77 ? 30   DC  T C5    1 
ATOM   13688 C  C6    . DC  E 4 30   ? 118.048 169.805 115.276 1.00 129.77 ? 30   DC  T C6    1 
ATOM   13689 P  P     . DG  E 4 31   ? 114.779 174.421 113.705 1.00 145.58 ? 31   DG  T P     1 
ATOM   13690 O  OP1   . DG  E 4 31   ? 114.437 175.597 112.876 1.00 145.58 ? 31   DG  T OP1   1 
ATOM   13691 O  OP2   . DG  E 4 31   ? 115.724 174.565 114.833 1.00 145.58 ? 31   DG  T OP2   1 
ATOM   13692 O  "O5'" . DG  E 4 31   ? 113.429 173.780 114.278 1.00 145.58 ? 31   DG  T "O5'" 1 
ATOM   13693 C  "C5'" . DG  E 4 31   ? 112.473 173.212 113.387 1.00 145.58 ? 31   DG  T "C5'" 1 
ATOM   13694 C  "C4'" . DG  E 4 31   ? 111.566 172.234 114.116 1.00 145.58 ? 31   DG  T "C4'" 1 
ATOM   13695 O  "O4'" . DG  E 4 31   ? 112.371 171.350 114.939 1.00 145.58 ? 31   DG  T "O4'" 1 
ATOM   13696 C  "C3'" . DG  E 4 31   ? 110.555 172.872 115.062 1.00 145.58 ? 31   DG  T "C3'" 1 
ATOM   13697 O  "O3'" . DG  E 4 31   ? 109.368 172.093 115.105 1.00 145.58 ? 31   DG  T "O3'" 1 
ATOM   13698 C  "C2'" . DG  E 4 31   ? 111.286 172.846 116.398 1.00 145.58 ? 31   DG  T "C2'" 1 
ATOM   13699 C  "C1'" . DG  E 4 31   ? 112.047 171.530 116.305 1.00 145.58 ? 31   DG  T "C1'" 1 
ATOM   13700 N  N9    . DG  E 4 31   ? 113.285 171.523 117.079 1.00 145.58 ? 31   DG  T N9    1 
ATOM   13701 C  C8    . DG  E 4 31   ? 114.324 172.416 116.984 1.00 145.58 ? 31   DG  T C8    1 
ATOM   13702 N  N7    . DG  E 4 31   ? 115.305 172.160 117.802 1.00 145.58 ? 31   DG  T N7    1 
ATOM   13703 C  C5    . DG  E 4 31   ? 114.889 171.028 118.488 1.00 145.58 ? 31   DG  T C5    1 
ATOM   13704 C  C6    . DG  E 4 31   ? 115.538 170.292 119.504 1.00 145.58 ? 31   DG  T C6    1 
ATOM   13705 O  O6    . DG  E 4 31   ? 116.646 170.504 120.014 1.00 145.58 ? 31   DG  T O6    1 
ATOM   13706 N  N1    . DG  E 4 31   ? 114.770 169.212 119.928 1.00 145.58 ? 31   DG  T N1    1 
ATOM   13707 C  C2    . DG  E 4 31   ? 113.529 168.886 119.432 1.00 145.58 ? 31   DG  T C2    1 
ATOM   13708 N  N2    . DG  E 4 31   ? 112.937 167.807 119.961 1.00 145.58 ? 31   DG  T N2    1 
ATOM   13709 N  N3    . DG  E 4 31   ? 112.911 169.569 118.478 1.00 145.58 ? 31   DG  T N3    1 
ATOM   13710 C  C4    . DG  E 4 31   ? 113.647 170.623 118.055 1.00 145.58 ? 31   DG  T C4    1 
ATOM   13711 P  P     . DA  E 4 32   ? 108.030 172.700 115.758 1.00 148.31 ? 32   DA  T P     1 
ATOM   13712 O  OP1   . DA  E 4 32   ? 106.899 172.333 114.879 1.00 148.31 ? 32   DA  T OP1   1 
ATOM   13713 O  OP2   . DA  E 4 32   ? 108.289 174.123 116.069 1.00 148.31 ? 32   DA  T OP2   1 
ATOM   13714 O  "O5'" . DA  E 4 32   ? 107.882 171.911 117.143 1.00 148.31 ? 32   DA  T "O5'" 1 
ATOM   13715 C  "C5'" . DA  E 4 32   ? 107.521 170.534 117.138 1.00 148.31 ? 32   DA  T "C5'" 1 
ATOM   13716 C  "C4'" . DA  E 4 32   ? 107.468 169.970 118.551 1.00 148.31 ? 32   DA  T "C4'" 1 
ATOM   13717 O  "O4'" . DA  E 4 32   ? 108.792 170.002 119.147 1.00 148.31 ? 32   DA  T "O4'" 1 
ATOM   13718 C  "C3'" . DA  E 4 32   ? 106.553 170.709 119.523 1.00 148.31 ? 32   DA  T "C3'" 1 
ATOM   13719 O  "O3'" . DA  E 4 32   ? 105.927 169.765 120.384 1.00 148.31 ? 32   DA  T "O3'" 1 
ATOM   13720 C  "C2'" . DA  E 4 32   ? 107.526 171.609 120.285 1.00 148.31 ? 32   DA  T "C2'" 1 
ATOM   13721 C  "C1'" . DA  E 4 32   ? 108.751 170.716 120.367 1.00 148.31 ? 32   DA  T "C1'" 1 
ATOM   13722 N  N9    . DA  E 4 32   ? 110.007 171.444 120.499 1.00 148.31 ? 32   DA  T N9    1 
ATOM   13723 C  C8    . DA  E 4 32   ? 110.399 172.546 119.792 1.00 148.31 ? 32   DA  T C8    1 
ATOM   13724 N  N7    . DA  E 4 32   ? 111.595 172.979 120.110 1.00 148.31 ? 32   DA  T N7    1 
ATOM   13725 C  C5    . DA  E 4 32   ? 112.019 172.096 121.087 1.00 148.31 ? 32   DA  T C5    1 
ATOM   13726 C  C6    . DA  E 4 32   ? 113.208 172.009 121.834 1.00 148.31 ? 32   DA  T C6    1 
ATOM   13727 N  N6    . DA  E 4 32   ? 114.223 172.866 121.696 1.00 148.31 ? 32   DA  T N6    1 
ATOM   13728 N  N1    . DA  E 4 32   ? 113.312 171.005 122.731 1.00 148.31 ? 32   DA  T N1    1 
ATOM   13729 C  C2    . DA  E 4 32   ? 112.292 170.150 122.864 1.00 148.31 ? 32   DA  T C2    1 
ATOM   13730 N  N3    . DA  E 4 32   ? 111.126 170.131 122.219 1.00 148.31 ? 32   DA  T N3    1 
ATOM   13731 C  C4    . DA  E 4 32   ? 111.054 171.140 121.336 1.00 148.31 ? 32   DA  T C4    1 
ATOM   13732 P  P     . DC  E 4 33   ? 104.886 170.236 121.513 1.00 143.23 ? 33   DC  T P     1 
ATOM   13733 O  OP1   . DC  E 4 33   ? 103.746 169.296 121.461 1.00 143.23 ? 33   DC  T OP1   1 
ATOM   13734 O  OP2   . DC  E 4 33   ? 104.638 171.688 121.369 1.00 143.23 ? 33   DC  T OP2   1 
ATOM   13735 O  "O5'" . DC  E 4 33   ? 105.678 169.988 122.881 1.00 143.23 ? 33   DC  T "O5'" 1 
ATOM   13736 C  "C5'" . DC  E 4 33   ? 106.138 168.678 123.198 1.00 143.23 ? 33   DC  T "C5'" 1 
ATOM   13737 C  "C4'" . DC  E 4 33   ? 106.779 168.634 124.575 1.00 143.23 ? 33   DC  T "C4'" 1 
ATOM   13738 O  "O4'" . DC  E 4 33   ? 108.092 169.248 124.530 1.00 143.23 ? 33   DC  T "O4'" 1 
ATOM   13739 C  "C3'" . DC  E 4 33   ? 106.009 169.354 125.679 1.00 143.23 ? 33   DC  T "C3'" 1 
ATOM   13740 O  "O3'" . DC  E 4 33   ? 106.074 168.588 126.874 1.00 143.23 ? 33   DC  T "O3'" 1 
ATOM   13741 C  "C2'" . DC  E 4 33   ? 106.757 170.682 125.813 1.00 143.23 ? 33   DC  T "C2'" 1 
ATOM   13742 C  "C1'" . DC  E 4 33   ? 108.185 170.260 125.510 1.00 143.23 ? 33   DC  T "C1'" 1 
ATOM   13743 N  N1    . DC  E 4 33   ? 109.033 171.350 124.957 1.00 143.23 ? 33   DC  T N1    1 
ATOM   13744 C  C2    . DC  E 4 33   ? 110.352 171.485 125.399 1.00 143.23 ? 33   DC  T C2    1 
ATOM   13745 O  O2    . DC  E 4 33   ? 110.779 170.700 126.252 1.00 143.23 ? 33   DC  T O2    1 
ATOM   13746 N  N3    . DC  E 4 33   ? 111.121 172.472 124.878 1.00 143.23 ? 33   DC  T N3    1 
ATOM   13747 C  C4    . DC  E 4 33   ? 110.616 173.294 123.956 1.00 143.23 ? 33   DC  T C4    1 
ATOM   13748 N  N4    . DC  E 4 33   ? 111.408 174.254 123.469 1.00 143.23 ? 33   DC  T N4    1 
ATOM   13749 C  C5    . DC  E 4 33   ? 109.274 173.167 123.490 1.00 143.23 ? 33   DC  T C5    1 
ATOM   13750 C  C6    . DC  E 4 33   ? 108.527 172.190 124.011 1.00 143.23 ? 33   DC  T C6    1 
ATOM   13751 P  P     . DC  E 4 34   ? 105.364 169.103 128.219 1.00 137.19 ? 34   DC  T P     1 
ATOM   13752 O  OP1   . DC  E 4 34   ? 104.879 167.908 128.946 1.00 137.19 ? 34   DC  T OP1   1 
ATOM   13753 O  OP2   . DC  E 4 34   ? 104.412 170.178 127.861 1.00 137.19 ? 34   DC  T OP2   1 
ATOM   13754 O  "O5'" . DC  E 4 34   ? 106.564 169.751 129.051 1.00 137.19 ? 34   DC  T "O5'" 1 
ATOM   13755 C  "C5'" . DC  E 4 34   ? 107.745 168.995 129.291 1.00 137.19 ? 34   DC  T "C5'" 1 
ATOM   13756 C  "C4'" . DC  E 4 34   ? 108.667 169.720 130.254 1.00 137.19 ? 34   DC  T "C4'" 1 
ATOM   13757 O  "O4'" . DC  E 4 34   ? 109.453 170.707 129.534 1.00 137.19 ? 34   DC  T "O4'" 1 
ATOM   13758 C  "C3'" . DC  E 4 34   ? 107.959 170.477 131.378 1.00 137.19 ? 34   DC  T "C3'" 1 
ATOM   13759 O  "O3'" . DC  E 4 34   ? 108.666 170.300 132.595 1.00 137.19 ? 34   DC  T "O3'" 1 
ATOM   13760 C  "C2'" . DC  E 4 34   ? 108.019 171.926 130.904 1.00 137.19 ? 34   DC  T "C2'" 1 
ATOM   13761 C  "C1'" . DC  E 4 34   ? 109.363 171.948 130.196 1.00 137.19 ? 34   DC  T "C1'" 1 
ATOM   13762 N  N1    . DC  E 4 34   ? 109.491 173.035 129.185 1.00 137.19 ? 34   DC  T N1    1 
ATOM   13763 C  C2    . DC  E 4 34   ? 110.718 173.690 129.019 1.00 137.19 ? 34   DC  T C2    1 
ATOM   13764 O  O2    . DC  E 4 34   ? 111.679 173.350 129.719 1.00 137.19 ? 34   DC  T O2    1 
ATOM   13765 N  N3    . DC  E 4 34   ? 110.814 174.677 128.093 1.00 137.19 ? 34   DC  T N3    1 
ATOM   13766 C  C4    . DC  E 4 34   ? 109.750 175.008 127.360 1.00 137.19 ? 34   DC  T C4    1 
ATOM   13767 N  N4    . DC  E 4 34   ? 109.887 175.986 126.460 1.00 137.19 ? 34   DC  T N4    1 
ATOM   13768 C  C5    . DC  E 4 34   ? 108.494 174.352 127.517 1.00 137.19 ? 34   DC  T C5    1 
ATOM   13769 C  C6    . DC  E 4 34   ? 108.411 173.382 128.431 1.00 137.19 ? 34   DC  T C6    1 
ATOM   13770 P  P     . DG  E 4 35   ? 107.869 170.148 133.981 1.00 133.93 ? 35   DG  T P     1 
ATOM   13771 O  OP1   . DG  E 4 35   ? 107.747 168.704 134.278 1.00 133.93 ? 35   DG  T OP1   1 
ATOM   13772 O  OP2   . DG  E 4 35   ? 106.655 170.990 133.894 1.00 133.93 ? 35   DG  T OP2   1 
ATOM   13773 O  "O5'" . DG  E 4 35   ? 108.851 170.808 135.056 1.00 133.93 ? 35   DG  T "O5'" 1 
ATOM   13774 C  "C5'" . DG  E 4 35   ? 110.172 170.306 135.209 1.00 133.93 ? 35   DG  T "C5'" 1 
ATOM   13775 C  "C4'" . DG  E 4 35   ? 111.166 171.440 135.383 1.00 133.93 ? 35   DG  T "C4'" 1 
ATOM   13776 O  "O4'" . DG  E 4 35   ? 111.088 172.334 134.242 1.00 133.93 ? 35   DG  T "O4'" 1 
ATOM   13777 C  "C3'" . DG  E 4 35   ? 110.947 172.313 136.617 1.00 133.93 ? 35   DG  T "C3'" 1 
ATOM   13778 O  "O3'" . DG  E 4 35   ? 112.201 172.709 137.153 1.00 133.93 ? 35   DG  T "O3'" 1 
ATOM   13779 C  "C2'" . DG  E 4 35   ? 110.182 173.506 136.053 1.00 133.93 ? 35   DG  T "C2'" 1 
ATOM   13780 C  "C1'" . DG  E 4 35   ? 110.830 173.648 134.686 1.00 133.93 ? 35   DG  T "C1'" 1 
ATOM   13781 N  N9    . DG  E 4 35   ? 109.984 174.311 133.698 1.00 133.93 ? 35   DG  T N9    1 
ATOM   13782 C  C8    . DG  E 4 35   ? 108.659 174.060 133.438 1.00 133.93 ? 35   DG  T C8    1 
ATOM   13783 N  N7    . DG  E 4 35   ? 108.165 174.810 132.492 1.00 133.93 ? 35   DG  T N7    1 
ATOM   13784 C  C5    . DG  E 4 35   ? 109.233 175.606 132.097 1.00 133.93 ? 35   DG  T C5    1 
ATOM   13785 C  C6    . DG  E 4 35   ? 109.303 176.614 131.106 1.00 133.93 ? 35   DG  T C6    1 
ATOM   13786 O  O6    . DG  E 4 35   ? 108.406 177.016 130.354 1.00 133.93 ? 35   DG  T O6    1 
ATOM   13787 N  N1    . DG  E 4 35   ? 110.577 177.173 131.031 1.00 133.93 ? 35   DG  T N1    1 
ATOM   13788 C  C2    . DG  E 4 35   ? 111.645 176.804 131.813 1.00 133.93 ? 35   DG  T C2    1 
ATOM   13789 N  N2    . DG  E 4 35   ? 112.798 177.453 131.603 1.00 133.93 ? 35   DG  T N2    1 
ATOM   13790 N  N3    . DG  E 4 35   ? 111.590 175.863 132.744 1.00 133.93 ? 35   DG  T N3    1 
ATOM   13791 C  C4    . DG  E 4 35   ? 110.359 175.309 132.830 1.00 133.93 ? 35   DG  T C4    1 
ATOM   13792 P  P     . DC  E 4 36   ? 112.328 173.105 138.704 1.00 132.44 ? 36   DC  T P     1 
ATOM   13793 O  OP1   . DC  E 4 36   ? 113.333 172.205 139.309 1.00 132.44 ? 36   DC  T OP1   1 
ATOM   13794 O  OP2   . DC  E 4 36   ? 110.962 173.166 139.267 1.00 132.44 ? 36   DC  T OP2   1 
ATOM   13795 O  "O5'" . DC  E 4 36   ? 112.923 174.589 138.676 1.00 132.44 ? 36   DC  T "O5'" 1 
ATOM   13796 C  "C5'" . DC  E 4 36   ? 114.304 174.794 138.406 1.00 132.44 ? 36   DC  T "C5'" 1 
ATOM   13797 C  "C4'" . DC  E 4 36   ? 114.565 176.224 137.971 1.00 132.44 ? 36   DC  T "C4'" 1 
ATOM   13798 O  "O4'" . DC  E 4 36   ? 113.983 176.443 136.669 1.00 132.44 ? 36   DC  T "O4'" 1 
ATOM   13799 C  "C3'" . DC  E 4 36   ? 113.940 177.286 138.855 1.00 132.44 ? 36   DC  T "C3'" 1 
ATOM   13800 O  "O3'" . DC  E 4 36   ? 114.805 177.581 139.944 1.00 132.44 ? 36   DC  T "O3'" 1 
ATOM   13801 C  "C2'" . DC  E 4 36   ? 113.819 178.474 137.901 1.00 132.44 ? 36   DC  T "C2'" 1 
ATOM   13802 C  "C1'" . DC  E 4 36   ? 113.596 177.799 136.541 1.00 132.44 ? 36   DC  T "C1'" 1 
ATOM   13803 N  N1    . DC  E 4 36   ? 112.180 177.850 136.066 1.00 132.44 ? 36   DC  T N1    1 
ATOM   13804 C  C2    . DC  E 4 36   ? 111.814 178.779 135.086 1.00 132.44 ? 36   DC  T C2    1 
ATOM   13805 O  O2    . DC  E 4 36   ? 112.675 179.543 134.635 1.00 132.44 ? 36   DC  T O2    1 
ATOM   13806 N  N3    . DC  E 4 36   ? 110.526 178.814 134.662 1.00 132.44 ? 36   DC  T N3    1 
ATOM   13807 C  C4    . DC  E 4 36   ? 109.631 177.969 135.177 1.00 132.44 ? 36   DC  T C4    1 
ATOM   13808 N  N4    . DC  E 4 36   ? 108.372 178.039 134.731 1.00 132.44 ? 36   DC  T N4    1 
ATOM   13809 C  C5    . DC  E 4 36   ? 109.985 177.016 136.176 1.00 132.44 ? 36   DC  T C5    1 
ATOM   13810 C  C6    . DC  E 4 36   ? 111.257 176.990 136.585 1.00 132.44 ? 36   DC  T C6    1 
HETATM 13811 CA CA    . CA  F 5 .    ? 146.570 121.426 94.513  1.00 54.56  ? 1301 CA  A CA    1 
HETATM 13812 CA CA    . CA  G 5 .    ? 114.266 127.367 91.298  1.00 29.93  ? 1302 CA  A CA    1 
HETATM 13813 CA CA    . CA  H 5 .    ? 109.115 130.669 91.468  1.00 50.99  ? 1303 CA  A CA    1 
HETATM 13814 N  N1    . DCP I 6 .    ? 143.380 129.644 93.301  1.00 68.70  ? 1304 DCP A N1    1 
HETATM 13815 C  C2    . DCP I 6 .    ? 142.933 130.769 92.576  1.00 68.70  ? 1304 DCP A C2    1 
HETATM 13816 N  N3    . DCP I 6 .    ? 143.641 131.918 92.605  1.00 68.70  ? 1304 DCP A N3    1 
HETATM 13817 C  C4    . DCP I 6 .    ? 144.777 132.007 93.328  1.00 68.70  ? 1304 DCP A C4    1 
HETATM 13818 C  C5    . DCP I 6 .    ? 145.230 130.909 94.050  1.00 68.70  ? 1304 DCP A C5    1 
HETATM 13819 C  C6    . DCP I 6 .    ? 144.504 129.726 94.023  1.00 68.70  ? 1304 DCP A C6    1 
HETATM 13820 O  O2    . DCP I 6 .    ? 141.882 130.716 91.901  1.00 68.70  ? 1304 DCP A O2    1 
HETATM 13821 N  N4    . DCP I 6 .    ? 145.475 133.167 93.344  1.00 68.70  ? 1304 DCP A N4    1 
HETATM 13822 C  "C1'" . DCP I 6 .    ? 142.623 128.387 93.292  1.00 68.70  ? 1304 DCP A "C1'" 1 
HETATM 13823 C  "C2'" . DCP I 6 .    ? 142.451 127.837 91.882  1.00 68.70  ? 1304 DCP A "C2'" 1 
HETATM 13824 C  "C3'" . DCP I 6 .    ? 143.199 126.521 91.862  1.00 68.70  ? 1304 DCP A "C3'" 1 
HETATM 13825 C  "C4'" . DCP I 6 .    ? 143.569 126.223 93.299  1.00 68.70  ? 1304 DCP A "C4'" 1 
HETATM 13826 O  "O4'" . DCP I 6 .    ? 143.337 127.410 94.054  1.00 68.70  ? 1304 DCP A "O4'" 1 
HETATM 13827 O  "O3'" . DCP I 6 .    ? 142.372 125.479 91.343  1.00 68.70  ? 1304 DCP A "O3'" 1 
HETATM 13828 C  "C5'" . DCP I 6 .    ? 145.028 125.809 93.395  1.00 68.70  ? 1304 DCP A "C5'" 1 
HETATM 13829 O  "O5'" . DCP I 6 .    ? 145.415 125.642 94.755  1.00 68.70  ? 1304 DCP A "O5'" 1 
HETATM 13830 P  PA    . DCP I 6 .    ? 146.531 124.541 95.106  1.00 68.70  ? 1304 DCP A PA    1 
HETATM 13831 O  O1A   . DCP I 6 .    ? 146.115 123.835 96.374  1.00 68.70  ? 1304 DCP A O1A   1 
HETATM 13832 O  O2A   . DCP I 6 .    ? 146.799 123.744 93.851  1.00 68.70  ? 1304 DCP A O2A   1 
HETATM 13833 O  O3A   . DCP I 6 .    ? 147.837 125.425 95.426  1.00 68.70  ? 1304 DCP A O3A   1 
HETATM 13834 P  PB    . DCP I 6 .    ? 149.296 124.744 95.410  1.00 68.70  ? 1304 DCP A PB    1 
HETATM 13835 O  O1B   . DCP I 6 .    ? 149.122 123.245 95.440  1.00 68.70  ? 1304 DCP A O1B   1 
HETATM 13836 O  O2B   . DCP I 6 .    ? 150.107 125.388 94.311  1.00 68.70  ? 1304 DCP A O2B   1 
HETATM 13837 O  O3B   . DCP I 6 .    ? 149.900 125.212 96.826  1.00 68.70  ? 1304 DCP A O3B   1 
HETATM 13838 P  PG    . DCP I 6 .    ? 151.174 124.484 97.487  1.00 68.70  ? 1304 DCP A PG    1 
HETATM 13839 O  O1G   . DCP I 6 .    ? 151.918 125.606 98.169  1.00 68.70  ? 1304 DCP A O1G   1 
HETATM 13840 O  O2G   . DCP I 6 .    ? 151.905 123.878 96.313  1.00 68.70  ? 1304 DCP A O2G   1 
HETATM 13841 O  O3G   . DCP I 6 .    ? 150.564 123.477 98.432  1.00 68.70  ? 1304 DCP A O3G   1 
# 
