data_9HZ1
# 
_entry.id   9HZ1 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9HZ1         pdb_00009hz1 10.2210/pdb9hz1/pdb 
WWPDB D_1292144543 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-04 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9HZ1 
_pdbx_database_status.recvd_initial_deposition_date   2025-01-12 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB . 8OZU unspecified 
PDB . 9HY7 unspecified 
PDB . 9HYJ unspecified 
PDB . 9HYX unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              fgallego@ibv.csic.es 
_pdbx_contact_author.name_first         Francisca 
_pdbx_contact_author.name_last          'Gallego del Sol' 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-9862-4505 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Marina, A.'          1 0000-0002-1334-5273 
'Gallego del Sol, F.' 2 0000-0001-9862-4505 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Int.J.Biol.Macromol. 
_citation.journal_id_ASTM           IJBMDR 
_citation.journal_id_CSD            0708 
_citation.journal_id_ISSN           0141-8130 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            311 
_citation.language                  ? 
_citation.page_first                143462 
_citation.page_last                 143462 
_citation.title                     
'Unveiling the structural bases of alpha-L-fucosidase B activity through mutants boosting transfucosylation efficiency.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.ijbiomac.2025.143462 
_citation.pdbx_database_id_PubMed   40286956 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Becerra, J.E.'       1 ? 
primary 'Gallego Del Sol, F.' 2 ? 
primary 'Rubio-Del-Campo, A.' 3 ? 
primary 'Rodriguez-Diaz, J.'  4 ? 
primary 'Monedero, V.'        5 ? 
primary 'Marina, A.'          6 ? 
primary 'Yebra, M.J.'         7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Alpha-L-fucosidase                                46882.848 6    ? ? ? ? 
2 non-polymer syn '4-nitrophenyl 6-deoxy-alpha-L-galactopyranoside' 285.250   6    ? ? ? ? 
3 water       nat water                                             18.015    1135 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MTEPLPRIQHYEDLGLGLFIHWGLYSQMAVGEWTELIHHRNQHDYEQLIKTFTAAQFDAKKIAHAAKAVGAKYIVLTTKH
HEGFFLYDTKGLSDFDVMHAPARRDLIAEFVAACREEDLLPFFYMATYDWHTPLYDDDFPAYLTYLQKSVEVLCRNYGPV
GGFWFDGNWNKKDADWHLPELYGMIRHYQPNAIIVSNTGLKNRGQVSDPEIDVVTYERRTPDEIYHGAPNEKYVAGEISI
TLNQHWGIAANDLNYKSPAEMIETVAHARHIGANILVNIGLTGTGAIPAAAQTYMHLLGRWTAMAAPVLYKGRPVPVTSA
HGTRDFVLHTSKHDFLCILDLQVVGKDNVVLGGEGVNPRSFVGIGQPIQRIHWLDNDEVLSFTQDLDKKVLTVDATGYPY
GSDWVVRIAQIDYE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MTEPLPRIQHYEDLGLGLFIHWGLYSQMAVGEWTELIHHRNQHDYEQLIKTFTAAQFDAKKIAHAAKAVGAKYIVLTTKH
HEGFFLYDTKGLSDFDVMHAPARRDLIAEFVAACREEDLLPFFYMATYDWHTPLYDDDFPAYLTYLQKSVEVLCRNYGPV
GGFWFDGNWNKKDADWHLPELYGMIRHYQPNAIIVSNTGLKNRGQVSDPEIDVVTYERRTPDEIYHGAPNEKYVAGEISI
TLNQHWGIAANDLNYKSPAEMIETVAHARHIGANILVNIGLTGTGAIPAAAQTYMHLLGRWTAMAAPVLYKGRPVPVTSA
HGTRDFVLHTSKHDFLCILDLQVVGKDNVVLGGEGVNPRSFVGIGQPIQRIHWLDNDEVLSFTQDLDKKVLTVDATGYPY
GSDWVVRIAQIDYE
;
_entity_poly.pdbx_strand_id                 A,B,C,D,E,F 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '4-nitrophenyl 6-deoxy-alpha-L-galactopyranoside' JFZ 
3 water                                             HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   THR n 
1 3   GLU n 
1 4   PRO n 
1 5   LEU n 
1 6   PRO n 
1 7   ARG n 
1 8   ILE n 
1 9   GLN n 
1 10  HIS n 
1 11  TYR n 
1 12  GLU n 
1 13  ASP n 
1 14  LEU n 
1 15  GLY n 
1 16  LEU n 
1 17  GLY n 
1 18  LEU n 
1 19  PHE n 
1 20  ILE n 
1 21  HIS n 
1 22  TRP n 
1 23  GLY n 
1 24  LEU n 
1 25  TYR n 
1 26  SER n 
1 27  GLN n 
1 28  MET n 
1 29  ALA n 
1 30  VAL n 
1 31  GLY n 
1 32  GLU n 
1 33  TRP n 
1 34  THR n 
1 35  GLU n 
1 36  LEU n 
1 37  ILE n 
1 38  HIS n 
1 39  HIS n 
1 40  ARG n 
1 41  ASN n 
1 42  GLN n 
1 43  HIS n 
1 44  ASP n 
1 45  TYR n 
1 46  GLU n 
1 47  GLN n 
1 48  LEU n 
1 49  ILE n 
1 50  LYS n 
1 51  THR n 
1 52  PHE n 
1 53  THR n 
1 54  ALA n 
1 55  ALA n 
1 56  GLN n 
1 57  PHE n 
1 58  ASP n 
1 59  ALA n 
1 60  LYS n 
1 61  LYS n 
1 62  ILE n 
1 63  ALA n 
1 64  HIS n 
1 65  ALA n 
1 66  ALA n 
1 67  LYS n 
1 68  ALA n 
1 69  VAL n 
1 70  GLY n 
1 71  ALA n 
1 72  LYS n 
1 73  TYR n 
1 74  ILE n 
1 75  VAL n 
1 76  LEU n 
1 77  THR n 
1 78  THR n 
1 79  LYS n 
1 80  HIS n 
1 81  HIS n 
1 82  GLU n 
1 83  GLY n 
1 84  PHE n 
1 85  PHE n 
1 86  LEU n 
1 87  TYR n 
1 88  ASP n 
1 89  THR n 
1 90  LYS n 
1 91  GLY n 
1 92  LEU n 
1 93  SER n 
1 94  ASP n 
1 95  PHE n 
1 96  ASP n 
1 97  VAL n 
1 98  MET n 
1 99  HIS n 
1 100 ALA n 
1 101 PRO n 
1 102 ALA n 
1 103 ARG n 
1 104 ARG n 
1 105 ASP n 
1 106 LEU n 
1 107 ILE n 
1 108 ALA n 
1 109 GLU n 
1 110 PHE n 
1 111 VAL n 
1 112 ALA n 
1 113 ALA n 
1 114 CYS n 
1 115 ARG n 
1 116 GLU n 
1 117 GLU n 
1 118 ASP n 
1 119 LEU n 
1 120 LEU n 
1 121 PRO n 
1 122 PHE n 
1 123 PHE n 
1 124 TYR n 
1 125 MET n 
1 126 ALA n 
1 127 THR n 
1 128 TYR n 
1 129 ASP n 
1 130 TRP n 
1 131 HIS n 
1 132 THR n 
1 133 PRO n 
1 134 LEU n 
1 135 TYR n 
1 136 ASP n 
1 137 ASP n 
1 138 ASP n 
1 139 PHE n 
1 140 PRO n 
1 141 ALA n 
1 142 TYR n 
1 143 LEU n 
1 144 THR n 
1 145 TYR n 
1 146 LEU n 
1 147 GLN n 
1 148 LYS n 
1 149 SER n 
1 150 VAL n 
1 151 GLU n 
1 152 VAL n 
1 153 LEU n 
1 154 CYS n 
1 155 ARG n 
1 156 ASN n 
1 157 TYR n 
1 158 GLY n 
1 159 PRO n 
1 160 VAL n 
1 161 GLY n 
1 162 GLY n 
1 163 PHE n 
1 164 TRP n 
1 165 PHE n 
1 166 ASP n 
1 167 GLY n 
1 168 ASN n 
1 169 TRP n 
1 170 ASN n 
1 171 LYS n 
1 172 LYS n 
1 173 ASP n 
1 174 ALA n 
1 175 ASP n 
1 176 TRP n 
1 177 HIS n 
1 178 LEU n 
1 179 PRO n 
1 180 GLU n 
1 181 LEU n 
1 182 TYR n 
1 183 GLY n 
1 184 MET n 
1 185 ILE n 
1 186 ARG n 
1 187 HIS n 
1 188 TYR n 
1 189 GLN n 
1 190 PRO n 
1 191 ASN n 
1 192 ALA n 
1 193 ILE n 
1 194 ILE n 
1 195 VAL n 
1 196 SER n 
1 197 ASN n 
1 198 THR n 
1 199 GLY n 
1 200 LEU n 
1 201 LYS n 
1 202 ASN n 
1 203 ARG n 
1 204 GLY n 
1 205 GLN n 
1 206 VAL n 
1 207 SER n 
1 208 ASP n 
1 209 PRO n 
1 210 GLU n 
1 211 ILE n 
1 212 ASP n 
1 213 VAL n 
1 214 VAL n 
1 215 THR n 
1 216 TYR n 
1 217 GLU n 
1 218 ARG n 
1 219 ARG n 
1 220 THR n 
1 221 PRO n 
1 222 ASP n 
1 223 GLU n 
1 224 ILE n 
1 225 TYR n 
1 226 HIS n 
1 227 GLY n 
1 228 ALA n 
1 229 PRO n 
1 230 ASN n 
1 231 GLU n 
1 232 LYS n 
1 233 TYR n 
1 234 VAL n 
1 235 ALA n 
1 236 GLY n 
1 237 GLU n 
1 238 ILE n 
1 239 SER n 
1 240 ILE n 
1 241 THR n 
1 242 LEU n 
1 243 ASN n 
1 244 GLN n 
1 245 HIS n 
1 246 TRP n 
1 247 GLY n 
1 248 ILE n 
1 249 ALA n 
1 250 ALA n 
1 251 ASN n 
1 252 ASP n 
1 253 LEU n 
1 254 ASN n 
1 255 TYR n 
1 256 LYS n 
1 257 SER n 
1 258 PRO n 
1 259 ALA n 
1 260 GLU n 
1 261 MET n 
1 262 ILE n 
1 263 GLU n 
1 264 THR n 
1 265 VAL n 
1 266 ALA n 
1 267 HIS n 
1 268 ALA n 
1 269 ARG n 
1 270 HIS n 
1 271 ILE n 
1 272 GLY n 
1 273 ALA n 
1 274 ASN n 
1 275 ILE n 
1 276 LEU n 
1 277 VAL n 
1 278 ASN n 
1 279 ILE n 
1 280 GLY n 
1 281 LEU n 
1 282 THR n 
1 283 GLY n 
1 284 THR n 
1 285 GLY n 
1 286 ALA n 
1 287 ILE n 
1 288 PRO n 
1 289 ALA n 
1 290 ALA n 
1 291 ALA n 
1 292 GLN n 
1 293 THR n 
1 294 TYR n 
1 295 MET n 
1 296 HIS n 
1 297 LEU n 
1 298 LEU n 
1 299 GLY n 
1 300 ARG n 
1 301 TRP n 
1 302 THR n 
1 303 ALA n 
1 304 MET n 
1 305 ALA n 
1 306 ALA n 
1 307 PRO n 
1 308 VAL n 
1 309 LEU n 
1 310 TYR n 
1 311 LYS n 
1 312 GLY n 
1 313 ARG n 
1 314 PRO n 
1 315 VAL n 
1 316 PRO n 
1 317 VAL n 
1 318 THR n 
1 319 SER n 
1 320 ALA n 
1 321 HIS n 
1 322 GLY n 
1 323 THR n 
1 324 ARG n 
1 325 ASP n 
1 326 PHE n 
1 327 VAL n 
1 328 LEU n 
1 329 HIS n 
1 330 THR n 
1 331 SER n 
1 332 LYS n 
1 333 HIS n 
1 334 ASP n 
1 335 PHE n 
1 336 LEU n 
1 337 CYS n 
1 338 ILE n 
1 339 LEU n 
1 340 ASP n 
1 341 LEU n 
1 342 GLN n 
1 343 VAL n 
1 344 VAL n 
1 345 GLY n 
1 346 LYS n 
1 347 ASP n 
1 348 ASN n 
1 349 VAL n 
1 350 VAL n 
1 351 LEU n 
1 352 GLY n 
1 353 GLY n 
1 354 GLU n 
1 355 GLY n 
1 356 VAL n 
1 357 ASN n 
1 358 PRO n 
1 359 ARG n 
1 360 SER n 
1 361 PHE n 
1 362 VAL n 
1 363 GLY n 
1 364 ILE n 
1 365 GLY n 
1 366 GLN n 
1 367 PRO n 
1 368 ILE n 
1 369 GLN n 
1 370 ARG n 
1 371 ILE n 
1 372 HIS n 
1 373 TRP n 
1 374 LEU n 
1 375 ASP n 
1 376 ASN n 
1 377 ASP n 
1 378 GLU n 
1 379 VAL n 
1 380 LEU n 
1 381 SER n 
1 382 PHE n 
1 383 THR n 
1 384 GLN n 
1 385 ASP n 
1 386 LEU n 
1 387 ASP n 
1 388 LYS n 
1 389 LYS n 
1 390 VAL n 
1 391 LEU n 
1 392 THR n 
1 393 VAL n 
1 394 ASP n 
1 395 ALA n 
1 396 THR n 
1 397 GLY n 
1 398 TYR n 
1 399 PRO n 
1 400 TYR n 
1 401 GLY n 
1 402 SER n 
1 403 ASP n 
1 404 TRP n 
1 405 VAL n 
1 406 VAL n 
1 407 ARG n 
1 408 ILE n 
1 409 ALA n 
1 410 GLN n 
1 411 ILE n 
1 412 ASP n 
1 413 TYR n 
1 414 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   414 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 LCBD_2849 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      Lactobacillaceae 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     33958 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                           ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                          ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                        ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                   ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                          ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                                         ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                   ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                           ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                         ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                                             ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                        ? 'C6 H13 N O2'    131.173 
JFZ L-saccharide        n '4-nitrophenyl 6-deoxy-alpha-L-galactopyranoside' 
;4-nitrophenyl-alpha-L-fucose; 4-nitrophenyl 6-deoxy-alpha-L-galactoside; 4-nitrophenyl 6-deoxy-L-galactoside; 4-nitrophenyl 6-deoxy-galactoside
;
'C12 H15 N O7'   285.250 
LEU 'L-peptide linking' y LEUCINE                                           ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                            ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                        ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                     ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                           ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                            ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                         ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                        ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                          ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                            ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   THR 2   2   2   THR THR A . n 
A 1 3   GLU 3   3   3   GLU GLU A . n 
A 1 4   PRO 4   4   4   PRO PRO A . n 
A 1 5   LEU 5   5   5   LEU LEU A . n 
A 1 6   PRO 6   6   6   PRO PRO A . n 
A 1 7   ARG 7   7   7   ARG ARG A . n 
A 1 8   ILE 8   8   8   ILE ILE A . n 
A 1 9   GLN 9   9   9   GLN GLN A . n 
A 1 10  HIS 10  10  10  HIS HIS A . n 
A 1 11  TYR 11  11  11  TYR TYR A . n 
A 1 12  GLU 12  12  12  GLU GLU A . n 
A 1 13  ASP 13  13  13  ASP ASP A . n 
A 1 14  LEU 14  14  14  LEU LEU A . n 
A 1 15  GLY 15  15  15  GLY GLY A . n 
A 1 16  LEU 16  16  16  LEU LEU A . n 
A 1 17  GLY 17  17  17  GLY GLY A . n 
A 1 18  LEU 18  18  18  LEU LEU A . n 
A 1 19  PHE 19  19  19  PHE PHE A . n 
A 1 20  ILE 20  20  20  ILE ILE A . n 
A 1 21  HIS 21  21  21  HIS HIS A . n 
A 1 22  TRP 22  22  22  TRP TRP A . n 
A 1 23  GLY 23  23  23  GLY GLY A . n 
A 1 24  LEU 24  24  24  LEU LEU A . n 
A 1 25  TYR 25  25  25  TYR TYR A . n 
A 1 26  SER 26  26  26  SER SER A . n 
A 1 27  GLN 27  27  27  GLN GLN A . n 
A 1 28  MET 28  28  28  MET MET A . n 
A 1 29  ALA 29  29  29  ALA ALA A . n 
A 1 30  VAL 30  30  30  VAL VAL A . n 
A 1 31  GLY 31  31  31  GLY GLY A . n 
A 1 32  GLU 32  32  32  GLU GLU A . n 
A 1 33  TRP 33  33  33  TRP TRP A . n 
A 1 34  THR 34  34  34  THR THR A . n 
A 1 35  GLU 35  35  35  GLU GLU A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  ILE 37  37  37  ILE ILE A . n 
A 1 38  HIS 38  38  38  HIS HIS A . n 
A 1 39  HIS 39  39  39  HIS HIS A . n 
A 1 40  ARG 40  40  40  ARG ARG A . n 
A 1 41  ASN 41  41  41  ASN ASN A . n 
A 1 42  GLN 42  42  42  GLN GLN A . n 
A 1 43  HIS 43  43  43  HIS HIS A . n 
A 1 44  ASP 44  44  44  ASP ASP A . n 
A 1 45  TYR 45  45  45  TYR TYR A . n 
A 1 46  GLU 46  46  46  GLU GLU A . n 
A 1 47  GLN 47  47  47  GLN GLN A . n 
A 1 48  LEU 48  48  48  LEU LEU A . n 
A 1 49  ILE 49  49  49  ILE ILE A . n 
A 1 50  LYS 50  50  50  LYS LYS A . n 
A 1 51  THR 51  51  51  THR THR A . n 
A 1 52  PHE 52  52  52  PHE PHE A . n 
A 1 53  THR 53  53  53  THR THR A . n 
A 1 54  ALA 54  54  54  ALA ALA A . n 
A 1 55  ALA 55  55  55  ALA ALA A . n 
A 1 56  GLN 56  56  56  GLN GLN A . n 
A 1 57  PHE 57  57  57  PHE PHE A . n 
A 1 58  ASP 58  58  58  ASP ASP A . n 
A 1 59  ALA 59  59  59  ALA ALA A . n 
A 1 60  LYS 60  60  60  LYS LYS A . n 
A 1 61  LYS 61  61  61  LYS LYS A . n 
A 1 62  ILE 62  62  62  ILE ILE A . n 
A 1 63  ALA 63  63  63  ALA ALA A . n 
A 1 64  HIS 64  64  64  HIS HIS A . n 
A 1 65  ALA 65  65  65  ALA ALA A . n 
A 1 66  ALA 66  66  66  ALA ALA A . n 
A 1 67  LYS 67  67  67  LYS LYS A . n 
A 1 68  ALA 68  68  68  ALA ALA A . n 
A 1 69  VAL 69  69  69  VAL VAL A . n 
A 1 70  GLY 70  70  70  GLY GLY A . n 
A 1 71  ALA 71  71  71  ALA ALA A . n 
A 1 72  LYS 72  72  72  LYS LYS A . n 
A 1 73  TYR 73  73  73  TYR TYR A . n 
A 1 74  ILE 74  74  74  ILE ILE A . n 
A 1 75  VAL 75  75  75  VAL VAL A . n 
A 1 76  LEU 76  76  76  LEU LEU A . n 
A 1 77  THR 77  77  77  THR THR A . n 
A 1 78  THR 78  78  78  THR THR A . n 
A 1 79  LYS 79  79  79  LYS LYS A . n 
A 1 80  HIS 80  80  80  HIS HIS A . n 
A 1 81  HIS 81  81  81  HIS HIS A . n 
A 1 82  GLU 82  82  82  GLU GLU A . n 
A 1 83  GLY 83  83  83  GLY GLY A . n 
A 1 84  PHE 84  84  84  PHE PHE A . n 
A 1 85  PHE 85  85  85  PHE PHE A . n 
A 1 86  LEU 86  86  86  LEU LEU A . n 
A 1 87  TYR 87  87  87  TYR TYR A . n 
A 1 88  ASP 88  88  88  ASP ASP A . n 
A 1 89  THR 89  89  89  THR THR A . n 
A 1 90  LYS 90  90  90  LYS LYS A . n 
A 1 91  GLY 91  91  91  GLY GLY A . n 
A 1 92  LEU 92  92  92  LEU LEU A . n 
A 1 93  SER 93  93  93  SER SER A . n 
A 1 94  ASP 94  94  94  ASP ASP A . n 
A 1 95  PHE 95  95  95  PHE PHE A . n 
A 1 96  ASP 96  96  96  ASP ASP A . n 
A 1 97  VAL 97  97  97  VAL VAL A . n 
A 1 98  MET 98  98  98  MET MET A . n 
A 1 99  HIS 99  99  99  HIS HIS A . n 
A 1 100 ALA 100 100 100 ALA ALA A . n 
A 1 101 PRO 101 101 101 PRO PRO A . n 
A 1 102 ALA 102 102 102 ALA ALA A . n 
A 1 103 ARG 103 103 103 ARG ARG A . n 
A 1 104 ARG 104 104 104 ARG ARG A . n 
A 1 105 ASP 105 105 105 ASP ASP A . n 
A 1 106 LEU 106 106 106 LEU LEU A . n 
A 1 107 ILE 107 107 107 ILE ILE A . n 
A 1 108 ALA 108 108 108 ALA ALA A . n 
A 1 109 GLU 109 109 109 GLU GLU A . n 
A 1 110 PHE 110 110 110 PHE PHE A . n 
A 1 111 VAL 111 111 111 VAL VAL A . n 
A 1 112 ALA 112 112 112 ALA ALA A . n 
A 1 113 ALA 113 113 113 ALA ALA A . n 
A 1 114 CYS 114 114 114 CYS CYS A . n 
A 1 115 ARG 115 115 115 ARG ARG A . n 
A 1 116 GLU 116 116 116 GLU GLU A . n 
A 1 117 GLU 117 117 117 GLU GLU A . n 
A 1 118 ASP 118 118 118 ASP ASP A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 LEU 120 120 120 LEU LEU A . n 
A 1 121 PRO 121 121 121 PRO PRO A . n 
A 1 122 PHE 122 122 122 PHE PHE A . n 
A 1 123 PHE 123 123 123 PHE PHE A . n 
A 1 124 TYR 124 124 124 TYR TYR A . n 
A 1 125 MET 125 125 125 MET MET A . n 
A 1 126 ALA 126 126 126 ALA ALA A . n 
A 1 127 THR 127 127 127 THR THR A . n 
A 1 128 TYR 128 128 128 TYR TYR A . n 
A 1 129 ASP 129 129 129 ASP ASP A . n 
A 1 130 TRP 130 130 130 TRP TRP A . n 
A 1 131 HIS 131 131 131 HIS HIS A . n 
A 1 132 THR 132 132 132 THR THR A . n 
A 1 133 PRO 133 133 133 PRO PRO A . n 
A 1 134 LEU 134 134 134 LEU LEU A . n 
A 1 135 TYR 135 135 135 TYR TYR A . n 
A 1 136 ASP 136 136 136 ASP ASP A . n 
A 1 137 ASP 137 137 137 ASP ASP A . n 
A 1 138 ASP 138 138 138 ASP ASP A . n 
A 1 139 PHE 139 139 139 PHE PHE A . n 
A 1 140 PRO 140 140 140 PRO PRO A . n 
A 1 141 ALA 141 141 141 ALA ALA A . n 
A 1 142 TYR 142 142 142 TYR TYR A . n 
A 1 143 LEU 143 143 143 LEU LEU A . n 
A 1 144 THR 144 144 144 THR THR A . n 
A 1 145 TYR 145 145 145 TYR TYR A . n 
A 1 146 LEU 146 146 146 LEU LEU A . n 
A 1 147 GLN 147 147 147 GLN GLN A . n 
A 1 148 LYS 148 148 148 LYS LYS A . n 
A 1 149 SER 149 149 149 SER SER A . n 
A 1 150 VAL 150 150 150 VAL VAL A . n 
A 1 151 GLU 151 151 151 GLU GLU A . n 
A 1 152 VAL 152 152 152 VAL VAL A . n 
A 1 153 LEU 153 153 153 LEU LEU A . n 
A 1 154 CYS 154 154 154 CYS CYS A . n 
A 1 155 ARG 155 155 155 ARG ARG A . n 
A 1 156 ASN 156 156 156 ASN ASN A . n 
A 1 157 TYR 157 157 157 TYR TYR A . n 
A 1 158 GLY 158 158 158 GLY GLY A . n 
A 1 159 PRO 159 159 159 PRO PRO A . n 
A 1 160 VAL 160 160 160 VAL VAL A . n 
A 1 161 GLY 161 161 161 GLY GLY A . n 
A 1 162 GLY 162 162 162 GLY GLY A . n 
A 1 163 PHE 163 163 163 PHE PHE A . n 
A 1 164 TRP 164 164 164 TRP TRP A . n 
A 1 165 PHE 165 165 165 PHE PHE A . n 
A 1 166 ASP 166 166 166 ASP ASP A . n 
A 1 167 GLY 167 167 167 GLY GLY A . n 
A 1 168 ASN 168 168 168 ASN ASN A . n 
A 1 169 TRP 169 169 169 TRP TRP A . n 
A 1 170 ASN 170 170 170 ASN ASN A . n 
A 1 171 LYS 171 171 171 LYS LYS A . n 
A 1 172 LYS 172 172 172 LYS LYS A . n 
A 1 173 ASP 173 173 173 ASP ASP A . n 
A 1 174 ALA 174 174 174 ALA ALA A . n 
A 1 175 ASP 175 175 175 ASP ASP A . n 
A 1 176 TRP 176 176 176 TRP TRP A . n 
A 1 177 HIS 177 177 177 HIS HIS A . n 
A 1 178 LEU 178 178 178 LEU LEU A . n 
A 1 179 PRO 179 179 179 PRO PRO A . n 
A 1 180 GLU 180 180 180 GLU GLU A . n 
A 1 181 LEU 181 181 181 LEU LEU A . n 
A 1 182 TYR 182 182 182 TYR TYR A . n 
A 1 183 GLY 183 183 183 GLY GLY A . n 
A 1 184 MET 184 184 184 MET MET A . n 
A 1 185 ILE 185 185 185 ILE ILE A . n 
A 1 186 ARG 186 186 186 ARG ARG A . n 
A 1 187 HIS 187 187 187 HIS HIS A . n 
A 1 188 TYR 188 188 188 TYR TYR A . n 
A 1 189 GLN 189 189 189 GLN GLN A . n 
A 1 190 PRO 190 190 190 PRO PRO A . n 
A 1 191 ASN 191 191 191 ASN ASN A . n 
A 1 192 ALA 192 192 192 ALA ALA A . n 
A 1 193 ILE 193 193 193 ILE ILE A . n 
A 1 194 ILE 194 194 194 ILE ILE A . n 
A 1 195 VAL 195 195 195 VAL VAL A . n 
A 1 196 SER 196 196 196 SER SER A . n 
A 1 197 ASN 197 197 197 ASN ASN A . n 
A 1 198 THR 198 198 198 THR THR A . n 
A 1 199 GLY 199 199 199 GLY GLY A . n 
A 1 200 LEU 200 200 200 LEU LEU A . n 
A 1 201 LYS 201 201 201 LYS LYS A . n 
A 1 202 ASN 202 202 ?   ?   ?   A . n 
A 1 203 ARG 203 203 ?   ?   ?   A . n 
A 1 204 GLY 204 204 ?   ?   ?   A . n 
A 1 205 GLN 205 205 205 GLN GLN A . n 
A 1 206 VAL 206 206 206 VAL VAL A . n 
A 1 207 SER 207 207 207 SER SER A . n 
A 1 208 ASP 208 208 208 ASP ASP A . n 
A 1 209 PRO 209 209 209 PRO PRO A . n 
A 1 210 GLU 210 210 210 GLU GLU A . n 
A 1 211 ILE 211 211 211 ILE ILE A . n 
A 1 212 ASP 212 212 212 ASP ASP A . n 
A 1 213 VAL 213 213 213 VAL VAL A . n 
A 1 214 VAL 214 214 214 VAL VAL A . n 
A 1 215 THR 215 215 215 THR THR A . n 
A 1 216 TYR 216 216 216 TYR TYR A . n 
A 1 217 GLU 217 217 217 GLU GLU A . n 
A 1 218 ARG 218 218 218 ARG ARG A . n 
A 1 219 ARG 219 219 219 ARG ARG A . n 
A 1 220 THR 220 220 220 THR THR A . n 
A 1 221 PRO 221 221 221 PRO PRO A . n 
A 1 222 ASP 222 222 222 ASP ASP A . n 
A 1 223 GLU 223 223 223 GLU GLU A . n 
A 1 224 ILE 224 224 224 ILE ILE A . n 
A 1 225 TYR 225 225 225 TYR TYR A . n 
A 1 226 HIS 226 226 226 HIS HIS A . n 
A 1 227 GLY 227 227 227 GLY GLY A . n 
A 1 228 ALA 228 228 228 ALA ALA A . n 
A 1 229 PRO 229 229 229 PRO PRO A . n 
A 1 230 ASN 230 230 230 ASN ASN A . n 
A 1 231 GLU 231 231 231 GLU GLU A . n 
A 1 232 LYS 232 232 232 LYS LYS A . n 
A 1 233 TYR 233 233 233 TYR TYR A . n 
A 1 234 VAL 234 234 234 VAL VAL A . n 
A 1 235 ALA 235 235 235 ALA ALA A . n 
A 1 236 GLY 236 236 236 GLY GLY A . n 
A 1 237 GLU 237 237 237 GLU GLU A . n 
A 1 238 ILE 238 238 238 ILE ILE A . n 
A 1 239 SER 239 239 239 SER SER A . n 
A 1 240 ILE 240 240 240 ILE ILE A . n 
A 1 241 THR 241 241 241 THR THR A . n 
A 1 242 LEU 242 242 242 LEU LEU A . n 
A 1 243 ASN 243 243 243 ASN ASN A . n 
A 1 244 GLN 244 244 244 GLN GLN A . n 
A 1 245 HIS 245 245 245 HIS HIS A . n 
A 1 246 TRP 246 246 246 TRP TRP A . n 
A 1 247 GLY 247 247 247 GLY GLY A . n 
A 1 248 ILE 248 248 248 ILE ILE A . n 
A 1 249 ALA 249 249 249 ALA ALA A . n 
A 1 250 ALA 250 250 250 ALA ALA A . n 
A 1 251 ASN 251 251 251 ASN ASN A . n 
A 1 252 ASP 252 252 252 ASP ASP A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 ASN 254 254 254 ASN ASN A . n 
A 1 255 TYR 255 255 255 TYR TYR A . n 
A 1 256 LYS 256 256 256 LYS LYS A . n 
A 1 257 SER 257 257 257 SER SER A . n 
A 1 258 PRO 258 258 258 PRO PRO A . n 
A 1 259 ALA 259 259 259 ALA ALA A . n 
A 1 260 GLU 260 260 260 GLU GLU A . n 
A 1 261 MET 261 261 261 MET MET A . n 
A 1 262 ILE 262 262 262 ILE ILE A . n 
A 1 263 GLU 263 263 263 GLU GLU A . n 
A 1 264 THR 264 264 264 THR THR A . n 
A 1 265 VAL 265 265 265 VAL VAL A . n 
A 1 266 ALA 266 266 266 ALA ALA A . n 
A 1 267 HIS 267 267 267 HIS HIS A . n 
A 1 268 ALA 268 268 268 ALA ALA A . n 
A 1 269 ARG 269 269 269 ARG ARG A . n 
A 1 270 HIS 270 270 270 HIS HIS A . n 
A 1 271 ILE 271 271 271 ILE ILE A . n 
A 1 272 GLY 272 272 272 GLY GLY A . n 
A 1 273 ALA 273 273 273 ALA ALA A . n 
A 1 274 ASN 274 274 274 ASN ASN A . n 
A 1 275 ILE 275 275 275 ILE ILE A . n 
A 1 276 LEU 276 276 276 LEU LEU A . n 
A 1 277 VAL 277 277 277 VAL VAL A . n 
A 1 278 ASN 278 278 278 ASN ASN A . n 
A 1 279 ILE 279 279 279 ILE ILE A . n 
A 1 280 GLY 280 280 280 GLY GLY A . n 
A 1 281 LEU 281 281 281 LEU LEU A . n 
A 1 282 THR 282 282 282 THR THR A . n 
A 1 283 GLY 283 283 283 GLY GLY A . n 
A 1 284 THR 284 284 284 THR THR A . n 
A 1 285 GLY 285 285 285 GLY GLY A . n 
A 1 286 ALA 286 286 286 ALA ALA A . n 
A 1 287 ILE 287 287 287 ILE ILE A . n 
A 1 288 PRO 288 288 288 PRO PRO A . n 
A 1 289 ALA 289 289 289 ALA ALA A . n 
A 1 290 ALA 290 290 290 ALA ALA A . n 
A 1 291 ALA 291 291 291 ALA ALA A . n 
A 1 292 GLN 292 292 292 GLN GLN A . n 
A 1 293 THR 293 293 293 THR THR A . n 
A 1 294 TYR 294 294 294 TYR TYR A . n 
A 1 295 MET 295 295 295 MET MET A . n 
A 1 296 HIS 296 296 296 HIS HIS A . n 
A 1 297 LEU 297 297 297 LEU LEU A . n 
A 1 298 LEU 298 298 298 LEU LEU A . n 
A 1 299 GLY 299 299 299 GLY GLY A . n 
A 1 300 ARG 300 300 300 ARG ARG A . n 
A 1 301 TRP 301 301 301 TRP TRP A . n 
A 1 302 THR 302 302 302 THR THR A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 MET 304 304 304 MET MET A . n 
A 1 305 ALA 305 305 305 ALA ALA A . n 
A 1 306 ALA 306 306 306 ALA ALA A . n 
A 1 307 PRO 307 307 307 PRO PRO A . n 
A 1 308 VAL 308 308 308 VAL VAL A . n 
A 1 309 LEU 309 309 309 LEU LEU A . n 
A 1 310 TYR 310 310 310 TYR TYR A . n 
A 1 311 LYS 311 311 311 LYS LYS A . n 
A 1 312 GLY 312 312 312 GLY GLY A . n 
A 1 313 ARG 313 313 313 ARG ARG A . n 
A 1 314 PRO 314 314 314 PRO PRO A . n 
A 1 315 VAL 315 315 315 VAL VAL A . n 
A 1 316 PRO 316 316 316 PRO PRO A . n 
A 1 317 VAL 317 317 317 VAL VAL A . n 
A 1 318 THR 318 318 318 THR THR A . n 
A 1 319 SER 319 319 319 SER SER A . n 
A 1 320 ALA 320 320 320 ALA ALA A . n 
A 1 321 HIS 321 321 321 HIS HIS A . n 
A 1 322 GLY 322 322 322 GLY GLY A . n 
A 1 323 THR 323 323 323 THR THR A . n 
A 1 324 ARG 324 324 324 ARG ARG A . n 
A 1 325 ASP 325 325 325 ASP ASP A . n 
A 1 326 PHE 326 326 326 PHE PHE A . n 
A 1 327 VAL 327 327 327 VAL VAL A . n 
A 1 328 LEU 328 328 328 LEU LEU A . n 
A 1 329 HIS 329 329 329 HIS HIS A . n 
A 1 330 THR 330 330 330 THR THR A . n 
A 1 331 SER 331 331 331 SER SER A . n 
A 1 332 LYS 332 332 332 LYS LYS A . n 
A 1 333 HIS 333 333 333 HIS HIS A . n 
A 1 334 ASP 334 334 334 ASP ASP A . n 
A 1 335 PHE 335 335 335 PHE PHE A . n 
A 1 336 LEU 336 336 336 LEU LEU A . n 
A 1 337 CYS 337 337 337 CYS CYS A . n 
A 1 338 ILE 338 338 338 ILE ILE A . n 
A 1 339 LEU 339 339 339 LEU LEU A . n 
A 1 340 ASP 340 340 340 ASP ASP A . n 
A 1 341 LEU 341 341 341 LEU LEU A . n 
A 1 342 GLN 342 342 342 GLN GLN A . n 
A 1 343 VAL 343 343 343 VAL VAL A . n 
A 1 344 VAL 344 344 344 VAL VAL A . n 
A 1 345 GLY 345 345 345 GLY GLY A . n 
A 1 346 LYS 346 346 346 LYS LYS A . n 
A 1 347 ASP 347 347 347 ASP ASP A . n 
A 1 348 ASN 348 348 348 ASN ASN A . n 
A 1 349 VAL 349 349 349 VAL VAL A . n 
A 1 350 VAL 350 350 350 VAL VAL A . n 
A 1 351 LEU 351 351 351 LEU LEU A . n 
A 1 352 GLY 352 352 352 GLY GLY A . n 
A 1 353 GLY 353 353 353 GLY GLY A . n 
A 1 354 GLU 354 354 354 GLU GLU A . n 
A 1 355 GLY 355 355 355 GLY GLY A . n 
A 1 356 VAL 356 356 356 VAL VAL A . n 
A 1 357 ASN 357 357 357 ASN ASN A . n 
A 1 358 PRO 358 358 358 PRO PRO A . n 
A 1 359 ARG 359 359 359 ARG ARG A . n 
A 1 360 SER 360 360 360 SER SER A . n 
A 1 361 PHE 361 361 361 PHE PHE A . n 
A 1 362 VAL 362 362 362 VAL VAL A . n 
A 1 363 GLY 363 363 363 GLY GLY A . n 
A 1 364 ILE 364 364 364 ILE ILE A . n 
A 1 365 GLY 365 365 365 GLY GLY A . n 
A 1 366 GLN 366 366 366 GLN GLN A . n 
A 1 367 PRO 367 367 367 PRO PRO A . n 
A 1 368 ILE 368 368 368 ILE ILE A . n 
A 1 369 GLN 369 369 369 GLN GLN A . n 
A 1 370 ARG 370 370 370 ARG ARG A . n 
A 1 371 ILE 371 371 371 ILE ILE A . n 
A 1 372 HIS 372 372 372 HIS HIS A . n 
A 1 373 TRP 373 373 373 TRP TRP A . n 
A 1 374 LEU 374 374 374 LEU LEU A . n 
A 1 375 ASP 375 375 375 ASP ASP A . n 
A 1 376 ASN 376 376 376 ASN ASN A . n 
A 1 377 ASP 377 377 377 ASP ASP A . n 
A 1 378 GLU 378 378 378 GLU GLU A . n 
A 1 379 VAL 379 379 379 VAL VAL A . n 
A 1 380 LEU 380 380 380 LEU LEU A . n 
A 1 381 SER 381 381 381 SER SER A . n 
A 1 382 PHE 382 382 382 PHE PHE A . n 
A 1 383 THR 383 383 383 THR THR A . n 
A 1 384 GLN 384 384 384 GLN GLN A . n 
A 1 385 ASP 385 385 385 ASP ASP A . n 
A 1 386 LEU 386 386 386 LEU LEU A . n 
A 1 387 ASP 387 387 387 ASP ASP A . n 
A 1 388 LYS 388 388 388 LYS LYS A . n 
A 1 389 LYS 389 389 389 LYS LYS A . n 
A 1 390 VAL 390 390 390 VAL VAL A . n 
A 1 391 LEU 391 391 391 LEU LEU A . n 
A 1 392 THR 392 392 392 THR THR A . n 
A 1 393 VAL 393 393 393 VAL VAL A . n 
A 1 394 ASP 394 394 394 ASP ASP A . n 
A 1 395 ALA 395 395 395 ALA ALA A . n 
A 1 396 THR 396 396 396 THR THR A . n 
A 1 397 GLY 397 397 397 GLY GLY A . n 
A 1 398 TYR 398 398 398 TYR TYR A . n 
A 1 399 PRO 399 399 399 PRO PRO A . n 
A 1 400 TYR 400 400 400 TYR TYR A . n 
A 1 401 GLY 401 401 401 GLY GLY A . n 
A 1 402 SER 402 402 402 SER SER A . n 
A 1 403 ASP 403 403 403 ASP ASP A . n 
A 1 404 TRP 404 404 404 TRP TRP A . n 
A 1 405 VAL 405 405 405 VAL VAL A . n 
A 1 406 VAL 406 406 406 VAL VAL A . n 
A 1 407 ARG 407 407 407 ARG ARG A . n 
A 1 408 ILE 408 408 408 ILE ILE A . n 
A 1 409 ALA 409 409 409 ALA ALA A . n 
A 1 410 GLN 410 410 410 GLN GLN A . n 
A 1 411 ILE 411 411 411 ILE ILE A . n 
A 1 412 ASP 412 412 412 ASP ASP A . n 
A 1 413 TYR 413 413 413 TYR TYR A . n 
A 1 414 GLU 414 414 414 GLU GLU A . n 
B 1 1   MET 1   1   1   MET MET B . n 
B 1 2   THR 2   2   2   THR THR B . n 
B 1 3   GLU 3   3   3   GLU GLU B . n 
B 1 4   PRO 4   4   4   PRO PRO B . n 
B 1 5   LEU 5   5   5   LEU LEU B . n 
B 1 6   PRO 6   6   6   PRO PRO B . n 
B 1 7   ARG 7   7   7   ARG ARG B . n 
B 1 8   ILE 8   8   8   ILE ILE B . n 
B 1 9   GLN 9   9   9   GLN GLN B . n 
B 1 10  HIS 10  10  10  HIS HIS B . n 
B 1 11  TYR 11  11  11  TYR TYR B . n 
B 1 12  GLU 12  12  12  GLU GLU B . n 
B 1 13  ASP 13  13  13  ASP ASP B . n 
B 1 14  LEU 14  14  14  LEU LEU B . n 
B 1 15  GLY 15  15  15  GLY GLY B . n 
B 1 16  LEU 16  16  16  LEU LEU B . n 
B 1 17  GLY 17  17  17  GLY GLY B . n 
B 1 18  LEU 18  18  18  LEU LEU B . n 
B 1 19  PHE 19  19  19  PHE PHE B . n 
B 1 20  ILE 20  20  20  ILE ILE B . n 
B 1 21  HIS 21  21  21  HIS HIS B . n 
B 1 22  TRP 22  22  22  TRP TRP B . n 
B 1 23  GLY 23  23  23  GLY GLY B . n 
B 1 24  LEU 24  24  24  LEU LEU B . n 
B 1 25  TYR 25  25  25  TYR TYR B . n 
B 1 26  SER 26  26  26  SER SER B . n 
B 1 27  GLN 27  27  27  GLN GLN B . n 
B 1 28  MET 28  28  28  MET MET B . n 
B 1 29  ALA 29  29  29  ALA ALA B . n 
B 1 30  VAL 30  30  30  VAL VAL B . n 
B 1 31  GLY 31  31  31  GLY GLY B . n 
B 1 32  GLU 32  32  32  GLU GLU B . n 
B 1 33  TRP 33  33  33  TRP TRP B . n 
B 1 34  THR 34  34  34  THR THR B . n 
B 1 35  GLU 35  35  35  GLU GLU B . n 
B 1 36  LEU 36  36  36  LEU LEU B . n 
B 1 37  ILE 37  37  37  ILE ILE B . n 
B 1 38  HIS 38  38  38  HIS HIS B . n 
B 1 39  HIS 39  39  39  HIS HIS B . n 
B 1 40  ARG 40  40  40  ARG ARG B . n 
B 1 41  ASN 41  41  41  ASN ASN B . n 
B 1 42  GLN 42  42  42  GLN GLN B . n 
B 1 43  HIS 43  43  43  HIS HIS B . n 
B 1 44  ASP 44  44  44  ASP ASP B . n 
B 1 45  TYR 45  45  45  TYR TYR B . n 
B 1 46  GLU 46  46  46  GLU GLU B . n 
B 1 47  GLN 47  47  47  GLN GLN B . n 
B 1 48  LEU 48  48  48  LEU LEU B . n 
B 1 49  ILE 49  49  49  ILE ILE B . n 
B 1 50  LYS 50  50  50  LYS LYS B . n 
B 1 51  THR 51  51  51  THR THR B . n 
B 1 52  PHE 52  52  52  PHE PHE B . n 
B 1 53  THR 53  53  53  THR THR B . n 
B 1 54  ALA 54  54  54  ALA ALA B . n 
B 1 55  ALA 55  55  55  ALA ALA B . n 
B 1 56  GLN 56  56  56  GLN GLN B . n 
B 1 57  PHE 57  57  57  PHE PHE B . n 
B 1 58  ASP 58  58  58  ASP ASP B . n 
B 1 59  ALA 59  59  59  ALA ALA B . n 
B 1 60  LYS 60  60  60  LYS LYS B . n 
B 1 61  LYS 61  61  61  LYS LYS B . n 
B 1 62  ILE 62  62  62  ILE ILE B . n 
B 1 63  ALA 63  63  63  ALA ALA B . n 
B 1 64  HIS 64  64  64  HIS HIS B . n 
B 1 65  ALA 65  65  65  ALA ALA B . n 
B 1 66  ALA 66  66  66  ALA ALA B . n 
B 1 67  LYS 67  67  67  LYS LYS B . n 
B 1 68  ALA 68  68  68  ALA ALA B . n 
B 1 69  VAL 69  69  69  VAL VAL B . n 
B 1 70  GLY 70  70  70  GLY GLY B . n 
B 1 71  ALA 71  71  71  ALA ALA B . n 
B 1 72  LYS 72  72  72  LYS LYS B . n 
B 1 73  TYR 73  73  73  TYR TYR B . n 
B 1 74  ILE 74  74  74  ILE ILE B . n 
B 1 75  VAL 75  75  75  VAL VAL B . n 
B 1 76  LEU 76  76  76  LEU LEU B . n 
B 1 77  THR 77  77  77  THR THR B . n 
B 1 78  THR 78  78  78  THR THR B . n 
B 1 79  LYS 79  79  79  LYS LYS B . n 
B 1 80  HIS 80  80  80  HIS HIS B . n 
B 1 81  HIS 81  81  81  HIS HIS B . n 
B 1 82  GLU 82  82  82  GLU GLU B . n 
B 1 83  GLY 83  83  83  GLY GLY B . n 
B 1 84  PHE 84  84  84  PHE PHE B . n 
B 1 85  PHE 85  85  85  PHE PHE B . n 
B 1 86  LEU 86  86  86  LEU LEU B . n 
B 1 87  TYR 87  87  87  TYR TYR B . n 
B 1 88  ASP 88  88  88  ASP ASP B . n 
B 1 89  THR 89  89  89  THR THR B . n 
B 1 90  LYS 90  90  90  LYS LYS B . n 
B 1 91  GLY 91  91  91  GLY GLY B . n 
B 1 92  LEU 92  92  92  LEU LEU B . n 
B 1 93  SER 93  93  93  SER SER B . n 
B 1 94  ASP 94  94  94  ASP ASP B . n 
B 1 95  PHE 95  95  95  PHE PHE B . n 
B 1 96  ASP 96  96  96  ASP ASP B . n 
B 1 97  VAL 97  97  97  VAL VAL B . n 
B 1 98  MET 98  98  98  MET MET B . n 
B 1 99  HIS 99  99  99  HIS HIS B . n 
B 1 100 ALA 100 100 100 ALA ALA B . n 
B 1 101 PRO 101 101 101 PRO PRO B . n 
B 1 102 ALA 102 102 102 ALA ALA B . n 
B 1 103 ARG 103 103 103 ARG ARG B . n 
B 1 104 ARG 104 104 104 ARG ARG B . n 
B 1 105 ASP 105 105 105 ASP ASP B . n 
B 1 106 LEU 106 106 106 LEU LEU B . n 
B 1 107 ILE 107 107 107 ILE ILE B . n 
B 1 108 ALA 108 108 108 ALA ALA B . n 
B 1 109 GLU 109 109 109 GLU GLU B . n 
B 1 110 PHE 110 110 110 PHE PHE B . n 
B 1 111 VAL 111 111 111 VAL VAL B . n 
B 1 112 ALA 112 112 112 ALA ALA B . n 
B 1 113 ALA 113 113 113 ALA ALA B . n 
B 1 114 CYS 114 114 114 CYS CYS B . n 
B 1 115 ARG 115 115 115 ARG ARG B . n 
B 1 116 GLU 116 116 116 GLU GLU B . n 
B 1 117 GLU 117 117 117 GLU GLU B . n 
B 1 118 ASP 118 118 118 ASP ASP B . n 
B 1 119 LEU 119 119 119 LEU LEU B . n 
B 1 120 LEU 120 120 120 LEU LEU B . n 
B 1 121 PRO 121 121 121 PRO PRO B . n 
B 1 122 PHE 122 122 122 PHE PHE B . n 
B 1 123 PHE 123 123 123 PHE PHE B . n 
B 1 124 TYR 124 124 124 TYR TYR B . n 
B 1 125 MET 125 125 125 MET MET B . n 
B 1 126 ALA 126 126 126 ALA ALA B . n 
B 1 127 THR 127 127 127 THR THR B . n 
B 1 128 TYR 128 128 128 TYR TYR B . n 
B 1 129 ASP 129 129 129 ASP ASP B . n 
B 1 130 TRP 130 130 130 TRP TRP B . n 
B 1 131 HIS 131 131 131 HIS HIS B . n 
B 1 132 THR 132 132 132 THR THR B . n 
B 1 133 PRO 133 133 133 PRO PRO B . n 
B 1 134 LEU 134 134 134 LEU LEU B . n 
B 1 135 TYR 135 135 135 TYR TYR B . n 
B 1 136 ASP 136 136 136 ASP ASP B . n 
B 1 137 ASP 137 137 137 ASP ASP B . n 
B 1 138 ASP 138 138 138 ASP ASP B . n 
B 1 139 PHE 139 139 139 PHE PHE B . n 
B 1 140 PRO 140 140 140 PRO PRO B . n 
B 1 141 ALA 141 141 141 ALA ALA B . n 
B 1 142 TYR 142 142 142 TYR TYR B . n 
B 1 143 LEU 143 143 143 LEU LEU B . n 
B 1 144 THR 144 144 144 THR THR B . n 
B 1 145 TYR 145 145 145 TYR TYR B . n 
B 1 146 LEU 146 146 146 LEU LEU B . n 
B 1 147 GLN 147 147 147 GLN GLN B . n 
B 1 148 LYS 148 148 148 LYS LYS B . n 
B 1 149 SER 149 149 149 SER SER B . n 
B 1 150 VAL 150 150 150 VAL VAL B . n 
B 1 151 GLU 151 151 151 GLU GLU B . n 
B 1 152 VAL 152 152 152 VAL VAL B . n 
B 1 153 LEU 153 153 153 LEU LEU B . n 
B 1 154 CYS 154 154 154 CYS CYS B . n 
B 1 155 ARG 155 155 155 ARG ARG B . n 
B 1 156 ASN 156 156 156 ASN ASN B . n 
B 1 157 TYR 157 157 157 TYR TYR B . n 
B 1 158 GLY 158 158 158 GLY GLY B . n 
B 1 159 PRO 159 159 159 PRO PRO B . n 
B 1 160 VAL 160 160 160 VAL VAL B . n 
B 1 161 GLY 161 161 161 GLY GLY B . n 
B 1 162 GLY 162 162 162 GLY GLY B . n 
B 1 163 PHE 163 163 163 PHE PHE B . n 
B 1 164 TRP 164 164 164 TRP TRP B . n 
B 1 165 PHE 165 165 165 PHE PHE B . n 
B 1 166 ASP 166 166 166 ASP ASP B . n 
B 1 167 GLY 167 167 167 GLY GLY B . n 
B 1 168 ASN 168 168 168 ASN ASN B . n 
B 1 169 TRP 169 169 169 TRP TRP B . n 
B 1 170 ASN 170 170 170 ASN ASN B . n 
B 1 171 LYS 171 171 171 LYS LYS B . n 
B 1 172 LYS 172 172 172 LYS LYS B . n 
B 1 173 ASP 173 173 173 ASP ASP B . n 
B 1 174 ALA 174 174 174 ALA ALA B . n 
B 1 175 ASP 175 175 175 ASP ASP B . n 
B 1 176 TRP 176 176 176 TRP TRP B . n 
B 1 177 HIS 177 177 177 HIS HIS B . n 
B 1 178 LEU 178 178 178 LEU LEU B . n 
B 1 179 PRO 179 179 179 PRO PRO B . n 
B 1 180 GLU 180 180 180 GLU GLU B . n 
B 1 181 LEU 181 181 181 LEU LEU B . n 
B 1 182 TYR 182 182 182 TYR TYR B . n 
B 1 183 GLY 183 183 183 GLY GLY B . n 
B 1 184 MET 184 184 184 MET MET B . n 
B 1 185 ILE 185 185 185 ILE ILE B . n 
B 1 186 ARG 186 186 186 ARG ARG B . n 
B 1 187 HIS 187 187 187 HIS HIS B . n 
B 1 188 TYR 188 188 188 TYR TYR B . n 
B 1 189 GLN 189 189 189 GLN GLN B . n 
B 1 190 PRO 190 190 190 PRO PRO B . n 
B 1 191 ASN 191 191 191 ASN ASN B . n 
B 1 192 ALA 192 192 192 ALA ALA B . n 
B 1 193 ILE 193 193 193 ILE ILE B . n 
B 1 194 ILE 194 194 194 ILE ILE B . n 
B 1 195 VAL 195 195 195 VAL VAL B . n 
B 1 196 SER 196 196 196 SER SER B . n 
B 1 197 ASN 197 197 197 ASN ASN B . n 
B 1 198 THR 198 198 198 THR THR B . n 
B 1 199 GLY 199 199 199 GLY GLY B . n 
B 1 200 LEU 200 200 200 LEU LEU B . n 
B 1 201 LYS 201 201 ?   ?   ?   B . n 
B 1 202 ASN 202 202 ?   ?   ?   B . n 
B 1 203 ARG 203 203 ?   ?   ?   B . n 
B 1 204 GLY 204 204 204 GLY GLY B . n 
B 1 205 GLN 205 205 205 GLN GLN B . n 
B 1 206 VAL 206 206 206 VAL VAL B . n 
B 1 207 SER 207 207 207 SER SER B . n 
B 1 208 ASP 208 208 208 ASP ASP B . n 
B 1 209 PRO 209 209 209 PRO PRO B . n 
B 1 210 GLU 210 210 210 GLU GLU B . n 
B 1 211 ILE 211 211 211 ILE ILE B . n 
B 1 212 ASP 212 212 212 ASP ASP B . n 
B 1 213 VAL 213 213 213 VAL VAL B . n 
B 1 214 VAL 214 214 214 VAL VAL B . n 
B 1 215 THR 215 215 215 THR THR B . n 
B 1 216 TYR 216 216 216 TYR TYR B . n 
B 1 217 GLU 217 217 217 GLU GLU B . n 
B 1 218 ARG 218 218 218 ARG ARG B . n 
B 1 219 ARG 219 219 219 ARG ARG B . n 
B 1 220 THR 220 220 220 THR THR B . n 
B 1 221 PRO 221 221 221 PRO PRO B . n 
B 1 222 ASP 222 222 222 ASP ASP B . n 
B 1 223 GLU 223 223 223 GLU GLU B . n 
B 1 224 ILE 224 224 224 ILE ILE B . n 
B 1 225 TYR 225 225 225 TYR TYR B . n 
B 1 226 HIS 226 226 226 HIS HIS B . n 
B 1 227 GLY 227 227 227 GLY GLY B . n 
B 1 228 ALA 228 228 228 ALA ALA B . n 
B 1 229 PRO 229 229 229 PRO PRO B . n 
B 1 230 ASN 230 230 230 ASN ASN B . n 
B 1 231 GLU 231 231 231 GLU GLU B . n 
B 1 232 LYS 232 232 232 LYS LYS B . n 
B 1 233 TYR 233 233 233 TYR TYR B . n 
B 1 234 VAL 234 234 234 VAL VAL B . n 
B 1 235 ALA 235 235 235 ALA ALA B . n 
B 1 236 GLY 236 236 236 GLY GLY B . n 
B 1 237 GLU 237 237 237 GLU GLU B . n 
B 1 238 ILE 238 238 238 ILE ILE B . n 
B 1 239 SER 239 239 239 SER SER B . n 
B 1 240 ILE 240 240 240 ILE ILE B . n 
B 1 241 THR 241 241 241 THR THR B . n 
B 1 242 LEU 242 242 242 LEU LEU B . n 
B 1 243 ASN 243 243 243 ASN ASN B . n 
B 1 244 GLN 244 244 244 GLN GLN B . n 
B 1 245 HIS 245 245 245 HIS HIS B . n 
B 1 246 TRP 246 246 246 TRP TRP B . n 
B 1 247 GLY 247 247 247 GLY GLY B . n 
B 1 248 ILE 248 248 248 ILE ILE B . n 
B 1 249 ALA 249 249 249 ALA ALA B . n 
B 1 250 ALA 250 250 250 ALA ALA B . n 
B 1 251 ASN 251 251 251 ASN ASN B . n 
B 1 252 ASP 252 252 252 ASP ASP B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 ASN 254 254 254 ASN ASN B . n 
B 1 255 TYR 255 255 255 TYR TYR B . n 
B 1 256 LYS 256 256 256 LYS LYS B . n 
B 1 257 SER 257 257 257 SER SER B . n 
B 1 258 PRO 258 258 258 PRO PRO B . n 
B 1 259 ALA 259 259 259 ALA ALA B . n 
B 1 260 GLU 260 260 260 GLU GLU B . n 
B 1 261 MET 261 261 261 MET MET B . n 
B 1 262 ILE 262 262 262 ILE ILE B . n 
B 1 263 GLU 263 263 263 GLU GLU B . n 
B 1 264 THR 264 264 264 THR THR B . n 
B 1 265 VAL 265 265 265 VAL VAL B . n 
B 1 266 ALA 266 266 266 ALA ALA B . n 
B 1 267 HIS 267 267 267 HIS HIS B . n 
B 1 268 ALA 268 268 268 ALA ALA B . n 
B 1 269 ARG 269 269 269 ARG ARG B . n 
B 1 270 HIS 270 270 270 HIS HIS B . n 
B 1 271 ILE 271 271 271 ILE ILE B . n 
B 1 272 GLY 272 272 272 GLY GLY B . n 
B 1 273 ALA 273 273 273 ALA ALA B . n 
B 1 274 ASN 274 274 274 ASN ASN B . n 
B 1 275 ILE 275 275 275 ILE ILE B . n 
B 1 276 LEU 276 276 276 LEU LEU B . n 
B 1 277 VAL 277 277 277 VAL VAL B . n 
B 1 278 ASN 278 278 278 ASN ASN B . n 
B 1 279 ILE 279 279 279 ILE ILE B . n 
B 1 280 GLY 280 280 280 GLY GLY B . n 
B 1 281 LEU 281 281 281 LEU LEU B . n 
B 1 282 THR 282 282 282 THR THR B . n 
B 1 283 GLY 283 283 283 GLY GLY B . n 
B 1 284 THR 284 284 284 THR THR B . n 
B 1 285 GLY 285 285 285 GLY GLY B . n 
B 1 286 ALA 286 286 286 ALA ALA B . n 
B 1 287 ILE 287 287 287 ILE ILE B . n 
B 1 288 PRO 288 288 288 PRO PRO B . n 
B 1 289 ALA 289 289 289 ALA ALA B . n 
B 1 290 ALA 290 290 290 ALA ALA B . n 
B 1 291 ALA 291 291 291 ALA ALA B . n 
B 1 292 GLN 292 292 292 GLN GLN B . n 
B 1 293 THR 293 293 293 THR THR B . n 
B 1 294 TYR 294 294 294 TYR TYR B . n 
B 1 295 MET 295 295 295 MET MET B . n 
B 1 296 HIS 296 296 296 HIS HIS B . n 
B 1 297 LEU 297 297 297 LEU LEU B . n 
B 1 298 LEU 298 298 298 LEU LEU B . n 
B 1 299 GLY 299 299 299 GLY GLY B . n 
B 1 300 ARG 300 300 300 ARG ARG B . n 
B 1 301 TRP 301 301 301 TRP TRP B . n 
B 1 302 THR 302 302 302 THR THR B . n 
B 1 303 ALA 303 303 303 ALA ALA B . n 
B 1 304 MET 304 304 304 MET MET B . n 
B 1 305 ALA 305 305 305 ALA ALA B . n 
B 1 306 ALA 306 306 306 ALA ALA B . n 
B 1 307 PRO 307 307 307 PRO PRO B . n 
B 1 308 VAL 308 308 308 VAL VAL B . n 
B 1 309 LEU 309 309 309 LEU LEU B . n 
B 1 310 TYR 310 310 310 TYR TYR B . n 
B 1 311 LYS 311 311 311 LYS LYS B . n 
B 1 312 GLY 312 312 312 GLY GLY B . n 
B 1 313 ARG 313 313 313 ARG ARG B . n 
B 1 314 PRO 314 314 314 PRO PRO B . n 
B 1 315 VAL 315 315 315 VAL VAL B . n 
B 1 316 PRO 316 316 316 PRO PRO B . n 
B 1 317 VAL 317 317 317 VAL VAL B . n 
B 1 318 THR 318 318 318 THR THR B . n 
B 1 319 SER 319 319 319 SER SER B . n 
B 1 320 ALA 320 320 320 ALA ALA B . n 
B 1 321 HIS 321 321 321 HIS HIS B . n 
B 1 322 GLY 322 322 322 GLY GLY B . n 
B 1 323 THR 323 323 323 THR THR B . n 
B 1 324 ARG 324 324 324 ARG ARG B . n 
B 1 325 ASP 325 325 325 ASP ASP B . n 
B 1 326 PHE 326 326 326 PHE PHE B . n 
B 1 327 VAL 327 327 327 VAL VAL B . n 
B 1 328 LEU 328 328 328 LEU LEU B . n 
B 1 329 HIS 329 329 329 HIS HIS B . n 
B 1 330 THR 330 330 330 THR THR B . n 
B 1 331 SER 331 331 331 SER SER B . n 
B 1 332 LYS 332 332 332 LYS LYS B . n 
B 1 333 HIS 333 333 333 HIS HIS B . n 
B 1 334 ASP 334 334 334 ASP ASP B . n 
B 1 335 PHE 335 335 335 PHE PHE B . n 
B 1 336 LEU 336 336 336 LEU LEU B . n 
B 1 337 CYS 337 337 337 CYS CYS B . n 
B 1 338 ILE 338 338 338 ILE ILE B . n 
B 1 339 LEU 339 339 339 LEU LEU B . n 
B 1 340 ASP 340 340 340 ASP ASP B . n 
B 1 341 LEU 341 341 341 LEU LEU B . n 
B 1 342 GLN 342 342 342 GLN GLN B . n 
B 1 343 VAL 343 343 343 VAL VAL B . n 
B 1 344 VAL 344 344 344 VAL VAL B . n 
B 1 345 GLY 345 345 345 GLY GLY B . n 
B 1 346 LYS 346 346 346 LYS LYS B . n 
B 1 347 ASP 347 347 347 ASP ASP B . n 
B 1 348 ASN 348 348 348 ASN ASN B . n 
B 1 349 VAL 349 349 349 VAL VAL B . n 
B 1 350 VAL 350 350 350 VAL VAL B . n 
B 1 351 LEU 351 351 351 LEU LEU B . n 
B 1 352 GLY 352 352 352 GLY GLY B . n 
B 1 353 GLY 353 353 353 GLY GLY B . n 
B 1 354 GLU 354 354 354 GLU GLU B . n 
B 1 355 GLY 355 355 355 GLY GLY B . n 
B 1 356 VAL 356 356 356 VAL VAL B . n 
B 1 357 ASN 357 357 357 ASN ASN B . n 
B 1 358 PRO 358 358 358 PRO PRO B . n 
B 1 359 ARG 359 359 359 ARG ARG B . n 
B 1 360 SER 360 360 360 SER SER B . n 
B 1 361 PHE 361 361 361 PHE PHE B . n 
B 1 362 VAL 362 362 362 VAL VAL B . n 
B 1 363 GLY 363 363 363 GLY GLY B . n 
B 1 364 ILE 364 364 364 ILE ILE B . n 
B 1 365 GLY 365 365 365 GLY GLY B . n 
B 1 366 GLN 366 366 366 GLN GLN B . n 
B 1 367 PRO 367 367 367 PRO PRO B . n 
B 1 368 ILE 368 368 368 ILE ILE B . n 
B 1 369 GLN 369 369 369 GLN GLN B . n 
B 1 370 ARG 370 370 370 ARG ARG B . n 
B 1 371 ILE 371 371 371 ILE ILE B . n 
B 1 372 HIS 372 372 372 HIS HIS B . n 
B 1 373 TRP 373 373 373 TRP TRP B . n 
B 1 374 LEU 374 374 374 LEU LEU B . n 
B 1 375 ASP 375 375 375 ASP ASP B . n 
B 1 376 ASN 376 376 376 ASN ASN B . n 
B 1 377 ASP 377 377 377 ASP ASP B . n 
B 1 378 GLU 378 378 378 GLU GLU B . n 
B 1 379 VAL 379 379 379 VAL VAL B . n 
B 1 380 LEU 380 380 380 LEU LEU B . n 
B 1 381 SER 381 381 381 SER SER B . n 
B 1 382 PHE 382 382 382 PHE PHE B . n 
B 1 383 THR 383 383 383 THR THR B . n 
B 1 384 GLN 384 384 384 GLN GLN B . n 
B 1 385 ASP 385 385 385 ASP ASP B . n 
B 1 386 LEU 386 386 386 LEU LEU B . n 
B 1 387 ASP 387 387 387 ASP ASP B . n 
B 1 388 LYS 388 388 388 LYS LYS B . n 
B 1 389 LYS 389 389 389 LYS LYS B . n 
B 1 390 VAL 390 390 390 VAL VAL B . n 
B 1 391 LEU 391 391 391 LEU LEU B . n 
B 1 392 THR 392 392 392 THR THR B . n 
B 1 393 VAL 393 393 393 VAL VAL B . n 
B 1 394 ASP 394 394 394 ASP ASP B . n 
B 1 395 ALA 395 395 395 ALA ALA B . n 
B 1 396 THR 396 396 396 THR THR B . n 
B 1 397 GLY 397 397 397 GLY GLY B . n 
B 1 398 TYR 398 398 398 TYR TYR B . n 
B 1 399 PRO 399 399 399 PRO PRO B . n 
B 1 400 TYR 400 400 400 TYR TYR B . n 
B 1 401 GLY 401 401 401 GLY GLY B . n 
B 1 402 SER 402 402 402 SER SER B . n 
B 1 403 ASP 403 403 403 ASP ASP B . n 
B 1 404 TRP 404 404 404 TRP TRP B . n 
B 1 405 VAL 405 405 405 VAL VAL B . n 
B 1 406 VAL 406 406 406 VAL VAL B . n 
B 1 407 ARG 407 407 407 ARG ARG B . n 
B 1 408 ILE 408 408 408 ILE ILE B . n 
B 1 409 ALA 409 409 409 ALA ALA B . n 
B 1 410 GLN 410 410 410 GLN GLN B . n 
B 1 411 ILE 411 411 411 ILE ILE B . n 
B 1 412 ASP 412 412 412 ASP ASP B . n 
B 1 413 TYR 413 413 413 TYR TYR B . n 
B 1 414 GLU 414 414 414 GLU GLU B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   THR 2   2   2   THR THR C . n 
C 1 3   GLU 3   3   3   GLU GLU C . n 
C 1 4   PRO 4   4   4   PRO PRO C . n 
C 1 5   LEU 5   5   5   LEU LEU C . n 
C 1 6   PRO 6   6   6   PRO PRO C . n 
C 1 7   ARG 7   7   7   ARG ARG C . n 
C 1 8   ILE 8   8   8   ILE ILE C . n 
C 1 9   GLN 9   9   9   GLN GLN C . n 
C 1 10  HIS 10  10  10  HIS HIS C . n 
C 1 11  TYR 11  11  11  TYR TYR C . n 
C 1 12  GLU 12  12  12  GLU GLU C . n 
C 1 13  ASP 13  13  13  ASP ASP C . n 
C 1 14  LEU 14  14  14  LEU LEU C . n 
C 1 15  GLY 15  15  15  GLY GLY C . n 
C 1 16  LEU 16  16  16  LEU LEU C . n 
C 1 17  GLY 17  17  17  GLY GLY C . n 
C 1 18  LEU 18  18  18  LEU LEU C . n 
C 1 19  PHE 19  19  19  PHE PHE C . n 
C 1 20  ILE 20  20  20  ILE ILE C . n 
C 1 21  HIS 21  21  21  HIS HIS C . n 
C 1 22  TRP 22  22  22  TRP TRP C . n 
C 1 23  GLY 23  23  23  GLY GLY C . n 
C 1 24  LEU 24  24  24  LEU LEU C . n 
C 1 25  TYR 25  25  25  TYR TYR C . n 
C 1 26  SER 26  26  26  SER SER C . n 
C 1 27  GLN 27  27  27  GLN GLN C . n 
C 1 28  MET 28  28  28  MET MET C . n 
C 1 29  ALA 29  29  29  ALA ALA C . n 
C 1 30  VAL 30  30  30  VAL VAL C . n 
C 1 31  GLY 31  31  31  GLY GLY C . n 
C 1 32  GLU 32  32  32  GLU GLU C . n 
C 1 33  TRP 33  33  33  TRP TRP C . n 
C 1 34  THR 34  34  34  THR THR C . n 
C 1 35  GLU 35  35  35  GLU GLU C . n 
C 1 36  LEU 36  36  36  LEU LEU C . n 
C 1 37  ILE 37  37  37  ILE ILE C . n 
C 1 38  HIS 38  38  38  HIS HIS C . n 
C 1 39  HIS 39  39  39  HIS HIS C . n 
C 1 40  ARG 40  40  40  ARG ARG C . n 
C 1 41  ASN 41  41  41  ASN ASN C . n 
C 1 42  GLN 42  42  42  GLN GLN C . n 
C 1 43  HIS 43  43  43  HIS HIS C . n 
C 1 44  ASP 44  44  44  ASP ASP C . n 
C 1 45  TYR 45  45  45  TYR TYR C . n 
C 1 46  GLU 46  46  46  GLU GLU C . n 
C 1 47  GLN 47  47  47  GLN GLN C . n 
C 1 48  LEU 48  48  48  LEU LEU C . n 
C 1 49  ILE 49  49  49  ILE ILE C . n 
C 1 50  LYS 50  50  50  LYS LYS C . n 
C 1 51  THR 51  51  51  THR THR C . n 
C 1 52  PHE 52  52  52  PHE PHE C . n 
C 1 53  THR 53  53  53  THR THR C . n 
C 1 54  ALA 54  54  54  ALA ALA C . n 
C 1 55  ALA 55  55  55  ALA ALA C . n 
C 1 56  GLN 56  56  56  GLN GLN C . n 
C 1 57  PHE 57  57  57  PHE PHE C . n 
C 1 58  ASP 58  58  58  ASP ASP C . n 
C 1 59  ALA 59  59  59  ALA ALA C . n 
C 1 60  LYS 60  60  60  LYS LYS C . n 
C 1 61  LYS 61  61  61  LYS LYS C . n 
C 1 62  ILE 62  62  62  ILE ILE C . n 
C 1 63  ALA 63  63  63  ALA ALA C . n 
C 1 64  HIS 64  64  64  HIS HIS C . n 
C 1 65  ALA 65  65  65  ALA ALA C . n 
C 1 66  ALA 66  66  66  ALA ALA C . n 
C 1 67  LYS 67  67  67  LYS LYS C . n 
C 1 68  ALA 68  68  68  ALA ALA C . n 
C 1 69  VAL 69  69  69  VAL VAL C . n 
C 1 70  GLY 70  70  70  GLY GLY C . n 
C 1 71  ALA 71  71  71  ALA ALA C . n 
C 1 72  LYS 72  72  72  LYS LYS C . n 
C 1 73  TYR 73  73  73  TYR TYR C . n 
C 1 74  ILE 74  74  74  ILE ILE C . n 
C 1 75  VAL 75  75  75  VAL VAL C . n 
C 1 76  LEU 76  76  76  LEU LEU C . n 
C 1 77  THR 77  77  77  THR THR C . n 
C 1 78  THR 78  78  78  THR THR C . n 
C 1 79  LYS 79  79  79  LYS LYS C . n 
C 1 80  HIS 80  80  80  HIS HIS C . n 
C 1 81  HIS 81  81  81  HIS HIS C . n 
C 1 82  GLU 82  82  82  GLU GLU C . n 
C 1 83  GLY 83  83  83  GLY GLY C . n 
C 1 84  PHE 84  84  84  PHE PHE C . n 
C 1 85  PHE 85  85  85  PHE PHE C . n 
C 1 86  LEU 86  86  86  LEU LEU C . n 
C 1 87  TYR 87  87  87  TYR TYR C . n 
C 1 88  ASP 88  88  88  ASP ASP C . n 
C 1 89  THR 89  89  89  THR THR C . n 
C 1 90  LYS 90  90  90  LYS LYS C . n 
C 1 91  GLY 91  91  91  GLY GLY C . n 
C 1 92  LEU 92  92  92  LEU LEU C . n 
C 1 93  SER 93  93  93  SER SER C . n 
C 1 94  ASP 94  94  94  ASP ASP C . n 
C 1 95  PHE 95  95  95  PHE PHE C . n 
C 1 96  ASP 96  96  96  ASP ASP C . n 
C 1 97  VAL 97  97  97  VAL VAL C . n 
C 1 98  MET 98  98  98  MET MET C . n 
C 1 99  HIS 99  99  99  HIS HIS C . n 
C 1 100 ALA 100 100 100 ALA ALA C . n 
C 1 101 PRO 101 101 101 PRO PRO C . n 
C 1 102 ALA 102 102 102 ALA ALA C . n 
C 1 103 ARG 103 103 103 ARG ARG C . n 
C 1 104 ARG 104 104 104 ARG ARG C . n 
C 1 105 ASP 105 105 105 ASP ASP C . n 
C 1 106 LEU 106 106 106 LEU LEU C . n 
C 1 107 ILE 107 107 107 ILE ILE C . n 
C 1 108 ALA 108 108 108 ALA ALA C . n 
C 1 109 GLU 109 109 109 GLU GLU C . n 
C 1 110 PHE 110 110 110 PHE PHE C . n 
C 1 111 VAL 111 111 111 VAL VAL C . n 
C 1 112 ALA 112 112 112 ALA ALA C . n 
C 1 113 ALA 113 113 113 ALA ALA C . n 
C 1 114 CYS 114 114 114 CYS CYS C . n 
C 1 115 ARG 115 115 115 ARG ARG C . n 
C 1 116 GLU 116 116 116 GLU GLU C . n 
C 1 117 GLU 117 117 117 GLU GLU C . n 
C 1 118 ASP 118 118 118 ASP ASP C . n 
C 1 119 LEU 119 119 119 LEU LEU C . n 
C 1 120 LEU 120 120 120 LEU LEU C . n 
C 1 121 PRO 121 121 121 PRO PRO C . n 
C 1 122 PHE 122 122 122 PHE PHE C . n 
C 1 123 PHE 123 123 123 PHE PHE C . n 
C 1 124 TYR 124 124 124 TYR TYR C . n 
C 1 125 MET 125 125 125 MET MET C . n 
C 1 126 ALA 126 126 126 ALA ALA C . n 
C 1 127 THR 127 127 127 THR THR C . n 
C 1 128 TYR 128 128 128 TYR TYR C . n 
C 1 129 ASP 129 129 129 ASP ASP C . n 
C 1 130 TRP 130 130 130 TRP TRP C . n 
C 1 131 HIS 131 131 131 HIS HIS C . n 
C 1 132 THR 132 132 132 THR THR C . n 
C 1 133 PRO 133 133 133 PRO PRO C . n 
C 1 134 LEU 134 134 134 LEU LEU C . n 
C 1 135 TYR 135 135 135 TYR TYR C . n 
C 1 136 ASP 136 136 136 ASP ASP C . n 
C 1 137 ASP 137 137 137 ASP ASP C . n 
C 1 138 ASP 138 138 138 ASP ASP C . n 
C 1 139 PHE 139 139 139 PHE PHE C . n 
C 1 140 PRO 140 140 140 PRO PRO C . n 
C 1 141 ALA 141 141 141 ALA ALA C . n 
C 1 142 TYR 142 142 142 TYR TYR C . n 
C 1 143 LEU 143 143 143 LEU LEU C . n 
C 1 144 THR 144 144 144 THR THR C . n 
C 1 145 TYR 145 145 145 TYR TYR C . n 
C 1 146 LEU 146 146 146 LEU LEU C . n 
C 1 147 GLN 147 147 147 GLN GLN C . n 
C 1 148 LYS 148 148 148 LYS LYS C . n 
C 1 149 SER 149 149 149 SER SER C . n 
C 1 150 VAL 150 150 150 VAL VAL C . n 
C 1 151 GLU 151 151 151 GLU GLU C . n 
C 1 152 VAL 152 152 152 VAL VAL C . n 
C 1 153 LEU 153 153 153 LEU LEU C . n 
C 1 154 CYS 154 154 154 CYS CYS C . n 
C 1 155 ARG 155 155 155 ARG ARG C . n 
C 1 156 ASN 156 156 156 ASN ASN C . n 
C 1 157 TYR 157 157 157 TYR TYR C . n 
C 1 158 GLY 158 158 158 GLY GLY C . n 
C 1 159 PRO 159 159 159 PRO PRO C . n 
C 1 160 VAL 160 160 160 VAL VAL C . n 
C 1 161 GLY 161 161 161 GLY GLY C . n 
C 1 162 GLY 162 162 162 GLY GLY C . n 
C 1 163 PHE 163 163 163 PHE PHE C . n 
C 1 164 TRP 164 164 164 TRP TRP C . n 
C 1 165 PHE 165 165 165 PHE PHE C . n 
C 1 166 ASP 166 166 166 ASP ASP C . n 
C 1 167 GLY 167 167 167 GLY GLY C . n 
C 1 168 ASN 168 168 168 ASN ASN C . n 
C 1 169 TRP 169 169 169 TRP TRP C . n 
C 1 170 ASN 170 170 170 ASN ASN C . n 
C 1 171 LYS 171 171 171 LYS LYS C . n 
C 1 172 LYS 172 172 172 LYS LYS C . n 
C 1 173 ASP 173 173 173 ASP ASP C . n 
C 1 174 ALA 174 174 174 ALA ALA C . n 
C 1 175 ASP 175 175 175 ASP ASP C . n 
C 1 176 TRP 176 176 176 TRP TRP C . n 
C 1 177 HIS 177 177 177 HIS HIS C . n 
C 1 178 LEU 178 178 178 LEU LEU C . n 
C 1 179 PRO 179 179 179 PRO PRO C . n 
C 1 180 GLU 180 180 180 GLU GLU C . n 
C 1 181 LEU 181 181 181 LEU LEU C . n 
C 1 182 TYR 182 182 182 TYR TYR C . n 
C 1 183 GLY 183 183 183 GLY GLY C . n 
C 1 184 MET 184 184 184 MET MET C . n 
C 1 185 ILE 185 185 185 ILE ILE C . n 
C 1 186 ARG 186 186 186 ARG ARG C . n 
C 1 187 HIS 187 187 187 HIS HIS C . n 
C 1 188 TYR 188 188 188 TYR TYR C . n 
C 1 189 GLN 189 189 189 GLN GLN C . n 
C 1 190 PRO 190 190 190 PRO PRO C . n 
C 1 191 ASN 191 191 191 ASN ASN C . n 
C 1 192 ALA 192 192 192 ALA ALA C . n 
C 1 193 ILE 193 193 193 ILE ILE C . n 
C 1 194 ILE 194 194 194 ILE ILE C . n 
C 1 195 VAL 195 195 195 VAL VAL C . n 
C 1 196 SER 196 196 196 SER SER C . n 
C 1 197 ASN 197 197 197 ASN ASN C . n 
C 1 198 THR 198 198 198 THR THR C . n 
C 1 199 GLY 199 199 ?   ?   ?   C . n 
C 1 200 LEU 200 200 ?   ?   ?   C . n 
C 1 201 LYS 201 201 ?   ?   ?   C . n 
C 1 202 ASN 202 202 ?   ?   ?   C . n 
C 1 203 ARG 203 203 ?   ?   ?   C . n 
C 1 204 GLY 204 204 ?   ?   ?   C . n 
C 1 205 GLN 205 205 205 GLN GLN C . n 
C 1 206 VAL 206 206 206 VAL VAL C . n 
C 1 207 SER 207 207 207 SER SER C . n 
C 1 208 ASP 208 208 208 ASP ASP C . n 
C 1 209 PRO 209 209 209 PRO PRO C . n 
C 1 210 GLU 210 210 210 GLU GLU C . n 
C 1 211 ILE 211 211 211 ILE ILE C . n 
C 1 212 ASP 212 212 212 ASP ASP C . n 
C 1 213 VAL 213 213 213 VAL VAL C . n 
C 1 214 VAL 214 214 214 VAL VAL C . n 
C 1 215 THR 215 215 215 THR THR C . n 
C 1 216 TYR 216 216 216 TYR TYR C . n 
C 1 217 GLU 217 217 217 GLU GLU C . n 
C 1 218 ARG 218 218 218 ARG ARG C . n 
C 1 219 ARG 219 219 219 ARG ARG C . n 
C 1 220 THR 220 220 220 THR THR C . n 
C 1 221 PRO 221 221 221 PRO PRO C . n 
C 1 222 ASP 222 222 222 ASP ASP C . n 
C 1 223 GLU 223 223 223 GLU GLU C . n 
C 1 224 ILE 224 224 224 ILE ILE C . n 
C 1 225 TYR 225 225 225 TYR TYR C . n 
C 1 226 HIS 226 226 226 HIS HIS C . n 
C 1 227 GLY 227 227 227 GLY GLY C . n 
C 1 228 ALA 228 228 228 ALA ALA C . n 
C 1 229 PRO 229 229 229 PRO PRO C . n 
C 1 230 ASN 230 230 230 ASN ASN C . n 
C 1 231 GLU 231 231 231 GLU GLU C . n 
C 1 232 LYS 232 232 232 LYS LYS C . n 
C 1 233 TYR 233 233 233 TYR TYR C . n 
C 1 234 VAL 234 234 234 VAL VAL C . n 
C 1 235 ALA 235 235 235 ALA ALA C . n 
C 1 236 GLY 236 236 236 GLY GLY C . n 
C 1 237 GLU 237 237 237 GLU GLU C . n 
C 1 238 ILE 238 238 238 ILE ILE C . n 
C 1 239 SER 239 239 239 SER SER C . n 
C 1 240 ILE 240 240 240 ILE ILE C . n 
C 1 241 THR 241 241 241 THR THR C . n 
C 1 242 LEU 242 242 242 LEU LEU C . n 
C 1 243 ASN 243 243 243 ASN ASN C . n 
C 1 244 GLN 244 244 244 GLN GLN C . n 
C 1 245 HIS 245 245 245 HIS HIS C . n 
C 1 246 TRP 246 246 246 TRP TRP C . n 
C 1 247 GLY 247 247 247 GLY GLY C . n 
C 1 248 ILE 248 248 248 ILE ILE C . n 
C 1 249 ALA 249 249 249 ALA ALA C . n 
C 1 250 ALA 250 250 250 ALA ALA C . n 
C 1 251 ASN 251 251 251 ASN ASN C . n 
C 1 252 ASP 252 252 252 ASP ASP C . n 
C 1 253 LEU 253 253 253 LEU LEU C . n 
C 1 254 ASN 254 254 254 ASN ASN C . n 
C 1 255 TYR 255 255 255 TYR TYR C . n 
C 1 256 LYS 256 256 256 LYS LYS C . n 
C 1 257 SER 257 257 257 SER SER C . n 
C 1 258 PRO 258 258 258 PRO PRO C . n 
C 1 259 ALA 259 259 259 ALA ALA C . n 
C 1 260 GLU 260 260 260 GLU GLU C . n 
C 1 261 MET 261 261 261 MET MET C . n 
C 1 262 ILE 262 262 262 ILE ILE C . n 
C 1 263 GLU 263 263 263 GLU GLU C . n 
C 1 264 THR 264 264 264 THR THR C . n 
C 1 265 VAL 265 265 265 VAL VAL C . n 
C 1 266 ALA 266 266 266 ALA ALA C . n 
C 1 267 HIS 267 267 267 HIS HIS C . n 
C 1 268 ALA 268 268 268 ALA ALA C . n 
C 1 269 ARG 269 269 269 ARG ARG C . n 
C 1 270 HIS 270 270 270 HIS HIS C . n 
C 1 271 ILE 271 271 271 ILE ILE C . n 
C 1 272 GLY 272 272 272 GLY GLY C . n 
C 1 273 ALA 273 273 273 ALA ALA C . n 
C 1 274 ASN 274 274 274 ASN ASN C . n 
C 1 275 ILE 275 275 275 ILE ILE C . n 
C 1 276 LEU 276 276 276 LEU LEU C . n 
C 1 277 VAL 277 277 277 VAL VAL C . n 
C 1 278 ASN 278 278 278 ASN ASN C . n 
C 1 279 ILE 279 279 279 ILE ILE C . n 
C 1 280 GLY 280 280 280 GLY GLY C . n 
C 1 281 LEU 281 281 281 LEU LEU C . n 
C 1 282 THR 282 282 282 THR THR C . n 
C 1 283 GLY 283 283 283 GLY GLY C . n 
C 1 284 THR 284 284 284 THR THR C . n 
C 1 285 GLY 285 285 285 GLY GLY C . n 
C 1 286 ALA 286 286 286 ALA ALA C . n 
C 1 287 ILE 287 287 287 ILE ILE C . n 
C 1 288 PRO 288 288 288 PRO PRO C . n 
C 1 289 ALA 289 289 289 ALA ALA C . n 
C 1 290 ALA 290 290 290 ALA ALA C . n 
C 1 291 ALA 291 291 291 ALA ALA C . n 
C 1 292 GLN 292 292 292 GLN GLN C . n 
C 1 293 THR 293 293 293 THR THR C . n 
C 1 294 TYR 294 294 294 TYR TYR C . n 
C 1 295 MET 295 295 295 MET MET C . n 
C 1 296 HIS 296 296 296 HIS HIS C . n 
C 1 297 LEU 297 297 297 LEU LEU C . n 
C 1 298 LEU 298 298 298 LEU LEU C . n 
C 1 299 GLY 299 299 299 GLY GLY C . n 
C 1 300 ARG 300 300 300 ARG ARG C . n 
C 1 301 TRP 301 301 301 TRP TRP C . n 
C 1 302 THR 302 302 302 THR THR C . n 
C 1 303 ALA 303 303 303 ALA ALA C . n 
C 1 304 MET 304 304 304 MET MET C . n 
C 1 305 ALA 305 305 305 ALA ALA C . n 
C 1 306 ALA 306 306 306 ALA ALA C . n 
C 1 307 PRO 307 307 307 PRO PRO C . n 
C 1 308 VAL 308 308 308 VAL VAL C . n 
C 1 309 LEU 309 309 309 LEU LEU C . n 
C 1 310 TYR 310 310 310 TYR TYR C . n 
C 1 311 LYS 311 311 311 LYS LYS C . n 
C 1 312 GLY 312 312 312 GLY GLY C . n 
C 1 313 ARG 313 313 313 ARG ARG C . n 
C 1 314 PRO 314 314 314 PRO PRO C . n 
C 1 315 VAL 315 315 315 VAL VAL C . n 
C 1 316 PRO 316 316 316 PRO PRO C . n 
C 1 317 VAL 317 317 317 VAL VAL C . n 
C 1 318 THR 318 318 318 THR THR C . n 
C 1 319 SER 319 319 319 SER SER C . n 
C 1 320 ALA 320 320 320 ALA ALA C . n 
C 1 321 HIS 321 321 321 HIS HIS C . n 
C 1 322 GLY 322 322 322 GLY GLY C . n 
C 1 323 THR 323 323 323 THR THR C . n 
C 1 324 ARG 324 324 324 ARG ARG C . n 
C 1 325 ASP 325 325 325 ASP ASP C . n 
C 1 326 PHE 326 326 326 PHE PHE C . n 
C 1 327 VAL 327 327 327 VAL VAL C . n 
C 1 328 LEU 328 328 328 LEU LEU C . n 
C 1 329 HIS 329 329 329 HIS HIS C . n 
C 1 330 THR 330 330 330 THR THR C . n 
C 1 331 SER 331 331 331 SER SER C . n 
C 1 332 LYS 332 332 332 LYS LYS C . n 
C 1 333 HIS 333 333 333 HIS HIS C . n 
C 1 334 ASP 334 334 334 ASP ASP C . n 
C 1 335 PHE 335 335 335 PHE PHE C . n 
C 1 336 LEU 336 336 336 LEU LEU C . n 
C 1 337 CYS 337 337 337 CYS CYS C . n 
C 1 338 ILE 338 338 338 ILE ILE C . n 
C 1 339 LEU 339 339 339 LEU LEU C . n 
C 1 340 ASP 340 340 340 ASP ASP C . n 
C 1 341 LEU 341 341 341 LEU LEU C . n 
C 1 342 GLN 342 342 342 GLN GLN C . n 
C 1 343 VAL 343 343 343 VAL VAL C . n 
C 1 344 VAL 344 344 344 VAL VAL C . n 
C 1 345 GLY 345 345 345 GLY GLY C . n 
C 1 346 LYS 346 346 346 LYS LYS C . n 
C 1 347 ASP 347 347 347 ASP ASP C . n 
C 1 348 ASN 348 348 348 ASN ASN C . n 
C 1 349 VAL 349 349 349 VAL VAL C . n 
C 1 350 VAL 350 350 350 VAL VAL C . n 
C 1 351 LEU 351 351 351 LEU LEU C . n 
C 1 352 GLY 352 352 352 GLY GLY C . n 
C 1 353 GLY 353 353 353 GLY GLY C . n 
C 1 354 GLU 354 354 354 GLU GLU C . n 
C 1 355 GLY 355 355 355 GLY GLY C . n 
C 1 356 VAL 356 356 356 VAL VAL C . n 
C 1 357 ASN 357 357 357 ASN ASN C . n 
C 1 358 PRO 358 358 358 PRO PRO C . n 
C 1 359 ARG 359 359 359 ARG ARG C . n 
C 1 360 SER 360 360 360 SER SER C . n 
C 1 361 PHE 361 361 361 PHE PHE C . n 
C 1 362 VAL 362 362 362 VAL VAL C . n 
C 1 363 GLY 363 363 363 GLY GLY C . n 
C 1 364 ILE 364 364 364 ILE ILE C . n 
C 1 365 GLY 365 365 365 GLY GLY C . n 
C 1 366 GLN 366 366 366 GLN GLN C . n 
C 1 367 PRO 367 367 367 PRO PRO C . n 
C 1 368 ILE 368 368 368 ILE ILE C . n 
C 1 369 GLN 369 369 369 GLN GLN C . n 
C 1 370 ARG 370 370 370 ARG ARG C . n 
C 1 371 ILE 371 371 371 ILE ILE C . n 
C 1 372 HIS 372 372 372 HIS HIS C . n 
C 1 373 TRP 373 373 373 TRP TRP C . n 
C 1 374 LEU 374 374 374 LEU LEU C . n 
C 1 375 ASP 375 375 375 ASP ASP C . n 
C 1 376 ASN 376 376 376 ASN ASN C . n 
C 1 377 ASP 377 377 377 ASP ASP C . n 
C 1 378 GLU 378 378 378 GLU GLU C . n 
C 1 379 VAL 379 379 379 VAL VAL C . n 
C 1 380 LEU 380 380 380 LEU LEU C . n 
C 1 381 SER 381 381 381 SER SER C . n 
C 1 382 PHE 382 382 382 PHE PHE C . n 
C 1 383 THR 383 383 383 THR THR C . n 
C 1 384 GLN 384 384 384 GLN GLN C . n 
C 1 385 ASP 385 385 385 ASP ASP C . n 
C 1 386 LEU 386 386 386 LEU LEU C . n 
C 1 387 ASP 387 387 387 ASP ASP C . n 
C 1 388 LYS 388 388 388 LYS LYS C . n 
C 1 389 LYS 389 389 389 LYS LYS C . n 
C 1 390 VAL 390 390 390 VAL VAL C . n 
C 1 391 LEU 391 391 391 LEU LEU C . n 
C 1 392 THR 392 392 392 THR THR C . n 
C 1 393 VAL 393 393 393 VAL VAL C . n 
C 1 394 ASP 394 394 394 ASP ASP C . n 
C 1 395 ALA 395 395 395 ALA ALA C . n 
C 1 396 THR 396 396 396 THR THR C . n 
C 1 397 GLY 397 397 397 GLY GLY C . n 
C 1 398 TYR 398 398 398 TYR TYR C . n 
C 1 399 PRO 399 399 399 PRO PRO C . n 
C 1 400 TYR 400 400 400 TYR TYR C . n 
C 1 401 GLY 401 401 401 GLY GLY C . n 
C 1 402 SER 402 402 402 SER SER C . n 
C 1 403 ASP 403 403 403 ASP ASP C . n 
C 1 404 TRP 404 404 404 TRP TRP C . n 
C 1 405 VAL 405 405 405 VAL VAL C . n 
C 1 406 VAL 406 406 406 VAL VAL C . n 
C 1 407 ARG 407 407 407 ARG ARG C . n 
C 1 408 ILE 408 408 408 ILE ILE C . n 
C 1 409 ALA 409 409 409 ALA ALA C . n 
C 1 410 GLN 410 410 410 GLN GLN C . n 
C 1 411 ILE 411 411 411 ILE ILE C . n 
C 1 412 ASP 412 412 412 ASP ASP C . n 
C 1 413 TYR 413 413 413 TYR TYR C . n 
C 1 414 GLU 414 414 414 GLU GLU C . n 
D 1 1   MET 1   1   ?   ?   ?   D . n 
D 1 2   THR 2   2   2   THR THR D . n 
D 1 3   GLU 3   3   3   GLU GLU D . n 
D 1 4   PRO 4   4   4   PRO PRO D . n 
D 1 5   LEU 5   5   5   LEU LEU D . n 
D 1 6   PRO 6   6   6   PRO PRO D . n 
D 1 7   ARG 7   7   7   ARG ARG D . n 
D 1 8   ILE 8   8   8   ILE ILE D . n 
D 1 9   GLN 9   9   9   GLN GLN D . n 
D 1 10  HIS 10  10  10  HIS HIS D . n 
D 1 11  TYR 11  11  11  TYR TYR D . n 
D 1 12  GLU 12  12  12  GLU GLU D . n 
D 1 13  ASP 13  13  13  ASP ASP D . n 
D 1 14  LEU 14  14  14  LEU LEU D . n 
D 1 15  GLY 15  15  15  GLY GLY D . n 
D 1 16  LEU 16  16  16  LEU LEU D . n 
D 1 17  GLY 17  17  17  GLY GLY D . n 
D 1 18  LEU 18  18  18  LEU LEU D . n 
D 1 19  PHE 19  19  19  PHE PHE D . n 
D 1 20  ILE 20  20  20  ILE ILE D . n 
D 1 21  HIS 21  21  21  HIS HIS D . n 
D 1 22  TRP 22  22  22  TRP TRP D . n 
D 1 23  GLY 23  23  23  GLY GLY D . n 
D 1 24  LEU 24  24  24  LEU LEU D . n 
D 1 25  TYR 25  25  25  TYR TYR D . n 
D 1 26  SER 26  26  26  SER SER D . n 
D 1 27  GLN 27  27  27  GLN GLN D . n 
D 1 28  MET 28  28  28  MET MET D . n 
D 1 29  ALA 29  29  29  ALA ALA D . n 
D 1 30  VAL 30  30  30  VAL VAL D . n 
D 1 31  GLY 31  31  31  GLY GLY D . n 
D 1 32  GLU 32  32  32  GLU GLU D . n 
D 1 33  TRP 33  33  33  TRP TRP D . n 
D 1 34  THR 34  34  34  THR THR D . n 
D 1 35  GLU 35  35  35  GLU GLU D . n 
D 1 36  LEU 36  36  36  LEU LEU D . n 
D 1 37  ILE 37  37  37  ILE ILE D . n 
D 1 38  HIS 38  38  38  HIS HIS D . n 
D 1 39  HIS 39  39  39  HIS HIS D . n 
D 1 40  ARG 40  40  40  ARG ARG D . n 
D 1 41  ASN 41  41  41  ASN ASN D . n 
D 1 42  GLN 42  42  42  GLN GLN D . n 
D 1 43  HIS 43  43  43  HIS HIS D . n 
D 1 44  ASP 44  44  44  ASP ASP D . n 
D 1 45  TYR 45  45  45  TYR TYR D . n 
D 1 46  GLU 46  46  46  GLU GLU D . n 
D 1 47  GLN 47  47  47  GLN GLN D . n 
D 1 48  LEU 48  48  48  LEU LEU D . n 
D 1 49  ILE 49  49  49  ILE ILE D . n 
D 1 50  LYS 50  50  50  LYS LYS D . n 
D 1 51  THR 51  51  51  THR THR D . n 
D 1 52  PHE 52  52  52  PHE PHE D . n 
D 1 53  THR 53  53  53  THR THR D . n 
D 1 54  ALA 54  54  54  ALA ALA D . n 
D 1 55  ALA 55  55  55  ALA ALA D . n 
D 1 56  GLN 56  56  56  GLN GLN D . n 
D 1 57  PHE 57  57  57  PHE PHE D . n 
D 1 58  ASP 58  58  58  ASP ASP D . n 
D 1 59  ALA 59  59  59  ALA ALA D . n 
D 1 60  LYS 60  60  60  LYS LYS D . n 
D 1 61  LYS 61  61  61  LYS LYS D . n 
D 1 62  ILE 62  62  62  ILE ILE D . n 
D 1 63  ALA 63  63  63  ALA ALA D . n 
D 1 64  HIS 64  64  64  HIS HIS D . n 
D 1 65  ALA 65  65  65  ALA ALA D . n 
D 1 66  ALA 66  66  66  ALA ALA D . n 
D 1 67  LYS 67  67  67  LYS LYS D . n 
D 1 68  ALA 68  68  68  ALA ALA D . n 
D 1 69  VAL 69  69  69  VAL VAL D . n 
D 1 70  GLY 70  70  70  GLY GLY D . n 
D 1 71  ALA 71  71  71  ALA ALA D . n 
D 1 72  LYS 72  72  72  LYS LYS D . n 
D 1 73  TYR 73  73  73  TYR TYR D . n 
D 1 74  ILE 74  74  74  ILE ILE D . n 
D 1 75  VAL 75  75  75  VAL VAL D . n 
D 1 76  LEU 76  76  76  LEU LEU D . n 
D 1 77  THR 77  77  77  THR THR D . n 
D 1 78  THR 78  78  78  THR THR D . n 
D 1 79  LYS 79  79  79  LYS LYS D . n 
D 1 80  HIS 80  80  80  HIS HIS D . n 
D 1 81  HIS 81  81  81  HIS HIS D . n 
D 1 82  GLU 82  82  82  GLU GLU D . n 
D 1 83  GLY 83  83  83  GLY GLY D . n 
D 1 84  PHE 84  84  84  PHE PHE D . n 
D 1 85  PHE 85  85  85  PHE PHE D . n 
D 1 86  LEU 86  86  86  LEU LEU D . n 
D 1 87  TYR 87  87  87  TYR TYR D . n 
D 1 88  ASP 88  88  88  ASP ASP D . n 
D 1 89  THR 89  89  89  THR THR D . n 
D 1 90  LYS 90  90  90  LYS LYS D . n 
D 1 91  GLY 91  91  91  GLY GLY D . n 
D 1 92  LEU 92  92  92  LEU LEU D . n 
D 1 93  SER 93  93  93  SER SER D . n 
D 1 94  ASP 94  94  94  ASP ASP D . n 
D 1 95  PHE 95  95  95  PHE PHE D . n 
D 1 96  ASP 96  96  96  ASP ASP D . n 
D 1 97  VAL 97  97  97  VAL VAL D . n 
D 1 98  MET 98  98  98  MET MET D . n 
D 1 99  HIS 99  99  99  HIS HIS D . n 
D 1 100 ALA 100 100 100 ALA ALA D . n 
D 1 101 PRO 101 101 101 PRO PRO D . n 
D 1 102 ALA 102 102 102 ALA ALA D . n 
D 1 103 ARG 103 103 103 ARG ARG D . n 
D 1 104 ARG 104 104 104 ARG ARG D . n 
D 1 105 ASP 105 105 105 ASP ASP D . n 
D 1 106 LEU 106 106 106 LEU LEU D . n 
D 1 107 ILE 107 107 107 ILE ILE D . n 
D 1 108 ALA 108 108 108 ALA ALA D . n 
D 1 109 GLU 109 109 109 GLU GLU D . n 
D 1 110 PHE 110 110 110 PHE PHE D . n 
D 1 111 VAL 111 111 111 VAL VAL D . n 
D 1 112 ALA 112 112 112 ALA ALA D . n 
D 1 113 ALA 113 113 113 ALA ALA D . n 
D 1 114 CYS 114 114 114 CYS CYS D . n 
D 1 115 ARG 115 115 115 ARG ARG D . n 
D 1 116 GLU 116 116 116 GLU GLU D . n 
D 1 117 GLU 117 117 117 GLU GLU D . n 
D 1 118 ASP 118 118 118 ASP ASP D . n 
D 1 119 LEU 119 119 119 LEU LEU D . n 
D 1 120 LEU 120 120 120 LEU LEU D . n 
D 1 121 PRO 121 121 121 PRO PRO D . n 
D 1 122 PHE 122 122 122 PHE PHE D . n 
D 1 123 PHE 123 123 123 PHE PHE D . n 
D 1 124 TYR 124 124 124 TYR TYR D . n 
D 1 125 MET 125 125 125 MET MET D . n 
D 1 126 ALA 126 126 126 ALA ALA D . n 
D 1 127 THR 127 127 127 THR THR D . n 
D 1 128 TYR 128 128 128 TYR TYR D . n 
D 1 129 ASP 129 129 129 ASP ASP D . n 
D 1 130 TRP 130 130 130 TRP TRP D . n 
D 1 131 HIS 131 131 131 HIS HIS D . n 
D 1 132 THR 132 132 132 THR THR D . n 
D 1 133 PRO 133 133 133 PRO PRO D . n 
D 1 134 LEU 134 134 134 LEU LEU D . n 
D 1 135 TYR 135 135 135 TYR TYR D . n 
D 1 136 ASP 136 136 136 ASP ASP D . n 
D 1 137 ASP 137 137 137 ASP ASP D . n 
D 1 138 ASP 138 138 138 ASP ASP D . n 
D 1 139 PHE 139 139 139 PHE PHE D . n 
D 1 140 PRO 140 140 140 PRO PRO D . n 
D 1 141 ALA 141 141 141 ALA ALA D . n 
D 1 142 TYR 142 142 142 TYR TYR D . n 
D 1 143 LEU 143 143 143 LEU LEU D . n 
D 1 144 THR 144 144 144 THR THR D . n 
D 1 145 TYR 145 145 145 TYR TYR D . n 
D 1 146 LEU 146 146 146 LEU LEU D . n 
D 1 147 GLN 147 147 147 GLN GLN D . n 
D 1 148 LYS 148 148 148 LYS LYS D . n 
D 1 149 SER 149 149 149 SER SER D . n 
D 1 150 VAL 150 150 150 VAL VAL D . n 
D 1 151 GLU 151 151 151 GLU GLU D . n 
D 1 152 VAL 152 152 152 VAL VAL D . n 
D 1 153 LEU 153 153 153 LEU LEU D . n 
D 1 154 CYS 154 154 154 CYS CYS D . n 
D 1 155 ARG 155 155 155 ARG ARG D . n 
D 1 156 ASN 156 156 156 ASN ASN D . n 
D 1 157 TYR 157 157 157 TYR TYR D . n 
D 1 158 GLY 158 158 158 GLY GLY D . n 
D 1 159 PRO 159 159 159 PRO PRO D . n 
D 1 160 VAL 160 160 160 VAL VAL D . n 
D 1 161 GLY 161 161 161 GLY GLY D . n 
D 1 162 GLY 162 162 162 GLY GLY D . n 
D 1 163 PHE 163 163 163 PHE PHE D . n 
D 1 164 TRP 164 164 164 TRP TRP D . n 
D 1 165 PHE 165 165 165 PHE PHE D . n 
D 1 166 ASP 166 166 166 ASP ASP D . n 
D 1 167 GLY 167 167 167 GLY GLY D . n 
D 1 168 ASN 168 168 168 ASN ASN D . n 
D 1 169 TRP 169 169 169 TRP TRP D . n 
D 1 170 ASN 170 170 170 ASN ASN D . n 
D 1 171 LYS 171 171 171 LYS LYS D . n 
D 1 172 LYS 172 172 172 LYS LYS D . n 
D 1 173 ASP 173 173 173 ASP ASP D . n 
D 1 174 ALA 174 174 174 ALA ALA D . n 
D 1 175 ASP 175 175 175 ASP ASP D . n 
D 1 176 TRP 176 176 176 TRP TRP D . n 
D 1 177 HIS 177 177 177 HIS HIS D . n 
D 1 178 LEU 178 178 178 LEU LEU D . n 
D 1 179 PRO 179 179 179 PRO PRO D . n 
D 1 180 GLU 180 180 180 GLU GLU D . n 
D 1 181 LEU 181 181 181 LEU LEU D . n 
D 1 182 TYR 182 182 182 TYR TYR D . n 
D 1 183 GLY 183 183 183 GLY GLY D . n 
D 1 184 MET 184 184 184 MET MET D . n 
D 1 185 ILE 185 185 185 ILE ILE D . n 
D 1 186 ARG 186 186 186 ARG ARG D . n 
D 1 187 HIS 187 187 187 HIS HIS D . n 
D 1 188 TYR 188 188 188 TYR TYR D . n 
D 1 189 GLN 189 189 189 GLN GLN D . n 
D 1 190 PRO 190 190 190 PRO PRO D . n 
D 1 191 ASN 191 191 191 ASN ASN D . n 
D 1 192 ALA 192 192 192 ALA ALA D . n 
D 1 193 ILE 193 193 193 ILE ILE D . n 
D 1 194 ILE 194 194 194 ILE ILE D . n 
D 1 195 VAL 195 195 195 VAL VAL D . n 
D 1 196 SER 196 196 196 SER SER D . n 
D 1 197 ASN 197 197 197 ASN ASN D . n 
D 1 198 THR 198 198 198 THR THR D . n 
D 1 199 GLY 199 199 ?   ?   ?   D . n 
D 1 200 LEU 200 200 ?   ?   ?   D . n 
D 1 201 LYS 201 201 ?   ?   ?   D . n 
D 1 202 ASN 202 202 ?   ?   ?   D . n 
D 1 203 ARG 203 203 ?   ?   ?   D . n 
D 1 204 GLY 204 204 ?   ?   ?   D . n 
D 1 205 GLN 205 205 205 GLN GLN D . n 
D 1 206 VAL 206 206 206 VAL VAL D . n 
D 1 207 SER 207 207 207 SER SER D . n 
D 1 208 ASP 208 208 208 ASP ASP D . n 
D 1 209 PRO 209 209 209 PRO PRO D . n 
D 1 210 GLU 210 210 210 GLU GLU D . n 
D 1 211 ILE 211 211 211 ILE ILE D . n 
D 1 212 ASP 212 212 212 ASP ASP D . n 
D 1 213 VAL 213 213 213 VAL VAL D . n 
D 1 214 VAL 214 214 214 VAL VAL D . n 
D 1 215 THR 215 215 215 THR THR D . n 
D 1 216 TYR 216 216 216 TYR TYR D . n 
D 1 217 GLU 217 217 217 GLU GLU D . n 
D 1 218 ARG 218 218 218 ARG ARG D . n 
D 1 219 ARG 219 219 219 ARG ARG D . n 
D 1 220 THR 220 220 220 THR THR D . n 
D 1 221 PRO 221 221 221 PRO PRO D . n 
D 1 222 ASP 222 222 222 ASP ASP D . n 
D 1 223 GLU 223 223 223 GLU GLU D . n 
D 1 224 ILE 224 224 224 ILE ILE D . n 
D 1 225 TYR 225 225 225 TYR TYR D . n 
D 1 226 HIS 226 226 226 HIS HIS D . n 
D 1 227 GLY 227 227 227 GLY GLY D . n 
D 1 228 ALA 228 228 228 ALA ALA D . n 
D 1 229 PRO 229 229 229 PRO PRO D . n 
D 1 230 ASN 230 230 230 ASN ASN D . n 
D 1 231 GLU 231 231 231 GLU GLU D . n 
D 1 232 LYS 232 232 232 LYS LYS D . n 
D 1 233 TYR 233 233 233 TYR TYR D . n 
D 1 234 VAL 234 234 234 VAL VAL D . n 
D 1 235 ALA 235 235 235 ALA ALA D . n 
D 1 236 GLY 236 236 236 GLY GLY D . n 
D 1 237 GLU 237 237 237 GLU GLU D . n 
D 1 238 ILE 238 238 238 ILE ILE D . n 
D 1 239 SER 239 239 239 SER SER D . n 
D 1 240 ILE 240 240 240 ILE ILE D . n 
D 1 241 THR 241 241 241 THR THR D . n 
D 1 242 LEU 242 242 242 LEU LEU D . n 
D 1 243 ASN 243 243 243 ASN ASN D . n 
D 1 244 GLN 244 244 244 GLN GLN D . n 
D 1 245 HIS 245 245 245 HIS HIS D . n 
D 1 246 TRP 246 246 246 TRP TRP D . n 
D 1 247 GLY 247 247 247 GLY GLY D . n 
D 1 248 ILE 248 248 248 ILE ILE D . n 
D 1 249 ALA 249 249 249 ALA ALA D . n 
D 1 250 ALA 250 250 250 ALA ALA D . n 
D 1 251 ASN 251 251 251 ASN ASN D . n 
D 1 252 ASP 252 252 252 ASP ASP D . n 
D 1 253 LEU 253 253 253 LEU LEU D . n 
D 1 254 ASN 254 254 254 ASN ASN D . n 
D 1 255 TYR 255 255 255 TYR TYR D . n 
D 1 256 LYS 256 256 256 LYS LYS D . n 
D 1 257 SER 257 257 257 SER SER D . n 
D 1 258 PRO 258 258 258 PRO PRO D . n 
D 1 259 ALA 259 259 259 ALA ALA D . n 
D 1 260 GLU 260 260 260 GLU GLU D . n 
D 1 261 MET 261 261 261 MET MET D . n 
D 1 262 ILE 262 262 262 ILE ILE D . n 
D 1 263 GLU 263 263 263 GLU GLU D . n 
D 1 264 THR 264 264 264 THR THR D . n 
D 1 265 VAL 265 265 265 VAL VAL D . n 
D 1 266 ALA 266 266 266 ALA ALA D . n 
D 1 267 HIS 267 267 267 HIS HIS D . n 
D 1 268 ALA 268 268 268 ALA ALA D . n 
D 1 269 ARG 269 269 269 ARG ARG D . n 
D 1 270 HIS 270 270 270 HIS HIS D . n 
D 1 271 ILE 271 271 271 ILE ILE D . n 
D 1 272 GLY 272 272 272 GLY GLY D . n 
D 1 273 ALA 273 273 273 ALA ALA D . n 
D 1 274 ASN 274 274 274 ASN ASN D . n 
D 1 275 ILE 275 275 275 ILE ILE D . n 
D 1 276 LEU 276 276 276 LEU LEU D . n 
D 1 277 VAL 277 277 277 VAL VAL D . n 
D 1 278 ASN 278 278 278 ASN ASN D . n 
D 1 279 ILE 279 279 279 ILE ILE D . n 
D 1 280 GLY 280 280 280 GLY GLY D . n 
D 1 281 LEU 281 281 281 LEU LEU D . n 
D 1 282 THR 282 282 282 THR THR D . n 
D 1 283 GLY 283 283 283 GLY GLY D . n 
D 1 284 THR 284 284 284 THR THR D . n 
D 1 285 GLY 285 285 285 GLY GLY D . n 
D 1 286 ALA 286 286 286 ALA ALA D . n 
D 1 287 ILE 287 287 287 ILE ILE D . n 
D 1 288 PRO 288 288 288 PRO PRO D . n 
D 1 289 ALA 289 289 289 ALA ALA D . n 
D 1 290 ALA 290 290 290 ALA ALA D . n 
D 1 291 ALA 291 291 291 ALA ALA D . n 
D 1 292 GLN 292 292 292 GLN GLN D . n 
D 1 293 THR 293 293 293 THR THR D . n 
D 1 294 TYR 294 294 294 TYR TYR D . n 
D 1 295 MET 295 295 295 MET MET D . n 
D 1 296 HIS 296 296 296 HIS HIS D . n 
D 1 297 LEU 297 297 297 LEU LEU D . n 
D 1 298 LEU 298 298 298 LEU LEU D . n 
D 1 299 GLY 299 299 299 GLY GLY D . n 
D 1 300 ARG 300 300 300 ARG ARG D . n 
D 1 301 TRP 301 301 301 TRP TRP D . n 
D 1 302 THR 302 302 302 THR THR D . n 
D 1 303 ALA 303 303 303 ALA ALA D . n 
D 1 304 MET 304 304 304 MET MET D . n 
D 1 305 ALA 305 305 305 ALA ALA D . n 
D 1 306 ALA 306 306 306 ALA ALA D . n 
D 1 307 PRO 307 307 307 PRO PRO D . n 
D 1 308 VAL 308 308 308 VAL VAL D . n 
D 1 309 LEU 309 309 309 LEU LEU D . n 
D 1 310 TYR 310 310 310 TYR TYR D . n 
D 1 311 LYS 311 311 311 LYS LYS D . n 
D 1 312 GLY 312 312 312 GLY GLY D . n 
D 1 313 ARG 313 313 313 ARG ARG D . n 
D 1 314 PRO 314 314 314 PRO PRO D . n 
D 1 315 VAL 315 315 315 VAL VAL D . n 
D 1 316 PRO 316 316 316 PRO PRO D . n 
D 1 317 VAL 317 317 317 VAL VAL D . n 
D 1 318 THR 318 318 318 THR THR D . n 
D 1 319 SER 319 319 319 SER SER D . n 
D 1 320 ALA 320 320 320 ALA ALA D . n 
D 1 321 HIS 321 321 321 HIS HIS D . n 
D 1 322 GLY 322 322 322 GLY GLY D . n 
D 1 323 THR 323 323 323 THR THR D . n 
D 1 324 ARG 324 324 324 ARG ARG D . n 
D 1 325 ASP 325 325 325 ASP ASP D . n 
D 1 326 PHE 326 326 326 PHE PHE D . n 
D 1 327 VAL 327 327 327 VAL VAL D . n 
D 1 328 LEU 328 328 328 LEU LEU D . n 
D 1 329 HIS 329 329 329 HIS HIS D . n 
D 1 330 THR 330 330 330 THR THR D . n 
D 1 331 SER 331 331 331 SER SER D . n 
D 1 332 LYS 332 332 332 LYS LYS D . n 
D 1 333 HIS 333 333 333 HIS HIS D . n 
D 1 334 ASP 334 334 334 ASP ASP D . n 
D 1 335 PHE 335 335 335 PHE PHE D . n 
D 1 336 LEU 336 336 336 LEU LEU D . n 
D 1 337 CYS 337 337 337 CYS CYS D . n 
D 1 338 ILE 338 338 338 ILE ILE D . n 
D 1 339 LEU 339 339 339 LEU LEU D . n 
D 1 340 ASP 340 340 340 ASP ASP D . n 
D 1 341 LEU 341 341 341 LEU LEU D . n 
D 1 342 GLN 342 342 342 GLN GLN D . n 
D 1 343 VAL 343 343 343 VAL VAL D . n 
D 1 344 VAL 344 344 344 VAL VAL D . n 
D 1 345 GLY 345 345 345 GLY GLY D . n 
D 1 346 LYS 346 346 346 LYS LYS D . n 
D 1 347 ASP 347 347 347 ASP ASP D . n 
D 1 348 ASN 348 348 348 ASN ASN D . n 
D 1 349 VAL 349 349 349 VAL VAL D . n 
D 1 350 VAL 350 350 350 VAL VAL D . n 
D 1 351 LEU 351 351 351 LEU LEU D . n 
D 1 352 GLY 352 352 352 GLY GLY D . n 
D 1 353 GLY 353 353 353 GLY GLY D . n 
D 1 354 GLU 354 354 354 GLU GLU D . n 
D 1 355 GLY 355 355 355 GLY GLY D . n 
D 1 356 VAL 356 356 356 VAL VAL D . n 
D 1 357 ASN 357 357 357 ASN ASN D . n 
D 1 358 PRO 358 358 358 PRO PRO D . n 
D 1 359 ARG 359 359 359 ARG ARG D . n 
D 1 360 SER 360 360 360 SER SER D . n 
D 1 361 PHE 361 361 361 PHE PHE D . n 
D 1 362 VAL 362 362 362 VAL VAL D . n 
D 1 363 GLY 363 363 363 GLY GLY D . n 
D 1 364 ILE 364 364 364 ILE ILE D . n 
D 1 365 GLY 365 365 365 GLY GLY D . n 
D 1 366 GLN 366 366 366 GLN GLN D . n 
D 1 367 PRO 367 367 367 PRO PRO D . n 
D 1 368 ILE 368 368 368 ILE ILE D . n 
D 1 369 GLN 369 369 369 GLN GLN D . n 
D 1 370 ARG 370 370 370 ARG ARG D . n 
D 1 371 ILE 371 371 371 ILE ILE D . n 
D 1 372 HIS 372 372 372 HIS HIS D . n 
D 1 373 TRP 373 373 373 TRP TRP D . n 
D 1 374 LEU 374 374 374 LEU LEU D . n 
D 1 375 ASP 375 375 375 ASP ASP D . n 
D 1 376 ASN 376 376 376 ASN ASN D . n 
D 1 377 ASP 377 377 377 ASP ASP D . n 
D 1 378 GLU 378 378 378 GLU GLU D . n 
D 1 379 VAL 379 379 379 VAL VAL D . n 
D 1 380 LEU 380 380 380 LEU LEU D . n 
D 1 381 SER 381 381 381 SER SER D . n 
D 1 382 PHE 382 382 382 PHE PHE D . n 
D 1 383 THR 383 383 383 THR THR D . n 
D 1 384 GLN 384 384 384 GLN GLN D . n 
D 1 385 ASP 385 385 385 ASP ASP D . n 
D 1 386 LEU 386 386 386 LEU LEU D . n 
D 1 387 ASP 387 387 387 ASP ASP D . n 
D 1 388 LYS 388 388 388 LYS LYS D . n 
D 1 389 LYS 389 389 389 LYS LYS D . n 
D 1 390 VAL 390 390 390 VAL VAL D . n 
D 1 391 LEU 391 391 391 LEU LEU D . n 
D 1 392 THR 392 392 392 THR THR D . n 
D 1 393 VAL 393 393 393 VAL VAL D . n 
D 1 394 ASP 394 394 394 ASP ASP D . n 
D 1 395 ALA 395 395 395 ALA ALA D . n 
D 1 396 THR 396 396 396 THR THR D . n 
D 1 397 GLY 397 397 397 GLY GLY D . n 
D 1 398 TYR 398 398 398 TYR TYR D . n 
D 1 399 PRO 399 399 399 PRO PRO D . n 
D 1 400 TYR 400 400 400 TYR TYR D . n 
D 1 401 GLY 401 401 401 GLY GLY D . n 
D 1 402 SER 402 402 402 SER SER D . n 
D 1 403 ASP 403 403 403 ASP ASP D . n 
D 1 404 TRP 404 404 404 TRP TRP D . n 
D 1 405 VAL 405 405 405 VAL VAL D . n 
D 1 406 VAL 406 406 406 VAL VAL D . n 
D 1 407 ARG 407 407 407 ARG ARG D . n 
D 1 408 ILE 408 408 408 ILE ILE D . n 
D 1 409 ALA 409 409 409 ALA ALA D . n 
D 1 410 GLN 410 410 410 GLN GLN D . n 
D 1 411 ILE 411 411 411 ILE ILE D . n 
D 1 412 ASP 412 412 412 ASP ASP D . n 
D 1 413 TYR 413 413 413 TYR TYR D . n 
D 1 414 GLU 414 414 414 GLU GLU D . n 
E 1 1   MET 1   1   ?   ?   ?   E . n 
E 1 2   THR 2   2   2   THR THR E . n 
E 1 3   GLU 3   3   3   GLU GLU E . n 
E 1 4   PRO 4   4   4   PRO PRO E . n 
E 1 5   LEU 5   5   5   LEU LEU E . n 
E 1 6   PRO 6   6   6   PRO PRO E . n 
E 1 7   ARG 7   7   7   ARG ARG E . n 
E 1 8   ILE 8   8   8   ILE ILE E . n 
E 1 9   GLN 9   9   9   GLN GLN E . n 
E 1 10  HIS 10  10  10  HIS HIS E . n 
E 1 11  TYR 11  11  11  TYR TYR E . n 
E 1 12  GLU 12  12  12  GLU GLU E . n 
E 1 13  ASP 13  13  13  ASP ASP E . n 
E 1 14  LEU 14  14  14  LEU LEU E . n 
E 1 15  GLY 15  15  15  GLY GLY E . n 
E 1 16  LEU 16  16  16  LEU LEU E . n 
E 1 17  GLY 17  17  17  GLY GLY E . n 
E 1 18  LEU 18  18  18  LEU LEU E . n 
E 1 19  PHE 19  19  19  PHE PHE E . n 
E 1 20  ILE 20  20  20  ILE ILE E . n 
E 1 21  HIS 21  21  21  HIS HIS E . n 
E 1 22  TRP 22  22  22  TRP TRP E . n 
E 1 23  GLY 23  23  23  GLY GLY E . n 
E 1 24  LEU 24  24  24  LEU LEU E . n 
E 1 25  TYR 25  25  25  TYR TYR E . n 
E 1 26  SER 26  26  26  SER SER E . n 
E 1 27  GLN 27  27  27  GLN GLN E . n 
E 1 28  MET 28  28  28  MET MET E . n 
E 1 29  ALA 29  29  29  ALA ALA E . n 
E 1 30  VAL 30  30  30  VAL VAL E . n 
E 1 31  GLY 31  31  31  GLY GLY E . n 
E 1 32  GLU 32  32  32  GLU GLU E . n 
E 1 33  TRP 33  33  33  TRP TRP E . n 
E 1 34  THR 34  34  34  THR THR E . n 
E 1 35  GLU 35  35  35  GLU GLU E . n 
E 1 36  LEU 36  36  36  LEU LEU E . n 
E 1 37  ILE 37  37  37  ILE ILE E . n 
E 1 38  HIS 38  38  38  HIS HIS E . n 
E 1 39  HIS 39  39  39  HIS HIS E . n 
E 1 40  ARG 40  40  40  ARG ARG E . n 
E 1 41  ASN 41  41  41  ASN ASN E . n 
E 1 42  GLN 42  42  42  GLN GLN E . n 
E 1 43  HIS 43  43  43  HIS HIS E . n 
E 1 44  ASP 44  44  44  ASP ASP E . n 
E 1 45  TYR 45  45  45  TYR TYR E . n 
E 1 46  GLU 46  46  46  GLU GLU E . n 
E 1 47  GLN 47  47  47  GLN GLN E . n 
E 1 48  LEU 48  48  48  LEU LEU E . n 
E 1 49  ILE 49  49  49  ILE ILE E . n 
E 1 50  LYS 50  50  50  LYS LYS E . n 
E 1 51  THR 51  51  51  THR THR E . n 
E 1 52  PHE 52  52  52  PHE PHE E . n 
E 1 53  THR 53  53  53  THR THR E . n 
E 1 54  ALA 54  54  54  ALA ALA E . n 
E 1 55  ALA 55  55  55  ALA ALA E . n 
E 1 56  GLN 56  56  56  GLN GLN E . n 
E 1 57  PHE 57  57  57  PHE PHE E . n 
E 1 58  ASP 58  58  58  ASP ASP E . n 
E 1 59  ALA 59  59  59  ALA ALA E . n 
E 1 60  LYS 60  60  60  LYS LYS E . n 
E 1 61  LYS 61  61  61  LYS LYS E . n 
E 1 62  ILE 62  62  62  ILE ILE E . n 
E 1 63  ALA 63  63  63  ALA ALA E . n 
E 1 64  HIS 64  64  64  HIS HIS E . n 
E 1 65  ALA 65  65  65  ALA ALA E . n 
E 1 66  ALA 66  66  66  ALA ALA E . n 
E 1 67  LYS 67  67  67  LYS LYS E . n 
E 1 68  ALA 68  68  68  ALA ALA E . n 
E 1 69  VAL 69  69  69  VAL VAL E . n 
E 1 70  GLY 70  70  70  GLY GLY E . n 
E 1 71  ALA 71  71  71  ALA ALA E . n 
E 1 72  LYS 72  72  72  LYS LYS E . n 
E 1 73  TYR 73  73  73  TYR TYR E . n 
E 1 74  ILE 74  74  74  ILE ILE E . n 
E 1 75  VAL 75  75  75  VAL VAL E . n 
E 1 76  LEU 76  76  76  LEU LEU E . n 
E 1 77  THR 77  77  77  THR THR E . n 
E 1 78  THR 78  78  78  THR THR E . n 
E 1 79  LYS 79  79  79  LYS LYS E . n 
E 1 80  HIS 80  80  80  HIS HIS E . n 
E 1 81  HIS 81  81  81  HIS HIS E . n 
E 1 82  GLU 82  82  82  GLU GLU E . n 
E 1 83  GLY 83  83  83  GLY GLY E . n 
E 1 84  PHE 84  84  84  PHE PHE E . n 
E 1 85  PHE 85  85  85  PHE PHE E . n 
E 1 86  LEU 86  86  86  LEU LEU E . n 
E 1 87  TYR 87  87  87  TYR TYR E . n 
E 1 88  ASP 88  88  88  ASP ASP E . n 
E 1 89  THR 89  89  89  THR THR E . n 
E 1 90  LYS 90  90  90  LYS LYS E . n 
E 1 91  GLY 91  91  91  GLY GLY E . n 
E 1 92  LEU 92  92  92  LEU LEU E . n 
E 1 93  SER 93  93  93  SER SER E . n 
E 1 94  ASP 94  94  94  ASP ASP E . n 
E 1 95  PHE 95  95  95  PHE PHE E . n 
E 1 96  ASP 96  96  96  ASP ASP E . n 
E 1 97  VAL 97  97  97  VAL VAL E . n 
E 1 98  MET 98  98  98  MET MET E . n 
E 1 99  HIS 99  99  99  HIS HIS E . n 
E 1 100 ALA 100 100 100 ALA ALA E . n 
E 1 101 PRO 101 101 101 PRO PRO E . n 
E 1 102 ALA 102 102 102 ALA ALA E . n 
E 1 103 ARG 103 103 103 ARG ARG E . n 
E 1 104 ARG 104 104 104 ARG ARG E . n 
E 1 105 ASP 105 105 105 ASP ASP E . n 
E 1 106 LEU 106 106 106 LEU LEU E . n 
E 1 107 ILE 107 107 107 ILE ILE E . n 
E 1 108 ALA 108 108 108 ALA ALA E . n 
E 1 109 GLU 109 109 109 GLU GLU E . n 
E 1 110 PHE 110 110 110 PHE PHE E . n 
E 1 111 VAL 111 111 111 VAL VAL E . n 
E 1 112 ALA 112 112 112 ALA ALA E . n 
E 1 113 ALA 113 113 113 ALA ALA E . n 
E 1 114 CYS 114 114 114 CYS CYS E . n 
E 1 115 ARG 115 115 115 ARG ARG E . n 
E 1 116 GLU 116 116 116 GLU GLU E . n 
E 1 117 GLU 117 117 117 GLU GLU E . n 
E 1 118 ASP 118 118 118 ASP ASP E . n 
E 1 119 LEU 119 119 119 LEU LEU E . n 
E 1 120 LEU 120 120 120 LEU LEU E . n 
E 1 121 PRO 121 121 121 PRO PRO E . n 
E 1 122 PHE 122 122 122 PHE PHE E . n 
E 1 123 PHE 123 123 123 PHE PHE E . n 
E 1 124 TYR 124 124 124 TYR TYR E . n 
E 1 125 MET 125 125 125 MET MET E . n 
E 1 126 ALA 126 126 126 ALA ALA E . n 
E 1 127 THR 127 127 127 THR THR E . n 
E 1 128 TYR 128 128 128 TYR TYR E . n 
E 1 129 ASP 129 129 129 ASP ASP E . n 
E 1 130 TRP 130 130 130 TRP TRP E . n 
E 1 131 HIS 131 131 131 HIS HIS E . n 
E 1 132 THR 132 132 132 THR THR E . n 
E 1 133 PRO 133 133 133 PRO PRO E . n 
E 1 134 LEU 134 134 134 LEU LEU E . n 
E 1 135 TYR 135 135 135 TYR TYR E . n 
E 1 136 ASP 136 136 136 ASP ASP E . n 
E 1 137 ASP 137 137 137 ASP ASP E . n 
E 1 138 ASP 138 138 138 ASP ASP E . n 
E 1 139 PHE 139 139 139 PHE PHE E . n 
E 1 140 PRO 140 140 140 PRO PRO E . n 
E 1 141 ALA 141 141 141 ALA ALA E . n 
E 1 142 TYR 142 142 142 TYR TYR E . n 
E 1 143 LEU 143 143 143 LEU LEU E . n 
E 1 144 THR 144 144 144 THR THR E . n 
E 1 145 TYR 145 145 145 TYR TYR E . n 
E 1 146 LEU 146 146 146 LEU LEU E . n 
E 1 147 GLN 147 147 147 GLN GLN E . n 
E 1 148 LYS 148 148 148 LYS LYS E . n 
E 1 149 SER 149 149 149 SER SER E . n 
E 1 150 VAL 150 150 150 VAL VAL E . n 
E 1 151 GLU 151 151 151 GLU GLU E . n 
E 1 152 VAL 152 152 152 VAL VAL E . n 
E 1 153 LEU 153 153 153 LEU LEU E . n 
E 1 154 CYS 154 154 154 CYS CYS E . n 
E 1 155 ARG 155 155 155 ARG ARG E . n 
E 1 156 ASN 156 156 156 ASN ASN E . n 
E 1 157 TYR 157 157 157 TYR TYR E . n 
E 1 158 GLY 158 158 158 GLY GLY E . n 
E 1 159 PRO 159 159 159 PRO PRO E . n 
E 1 160 VAL 160 160 160 VAL VAL E . n 
E 1 161 GLY 161 161 161 GLY GLY E . n 
E 1 162 GLY 162 162 162 GLY GLY E . n 
E 1 163 PHE 163 163 163 PHE PHE E . n 
E 1 164 TRP 164 164 164 TRP TRP E . n 
E 1 165 PHE 165 165 165 PHE PHE E . n 
E 1 166 ASP 166 166 166 ASP ASP E . n 
E 1 167 GLY 167 167 167 GLY GLY E . n 
E 1 168 ASN 168 168 168 ASN ASN E . n 
E 1 169 TRP 169 169 169 TRP TRP E . n 
E 1 170 ASN 170 170 170 ASN ASN E . n 
E 1 171 LYS 171 171 171 LYS LYS E . n 
E 1 172 LYS 172 172 172 LYS LYS E . n 
E 1 173 ASP 173 173 173 ASP ASP E . n 
E 1 174 ALA 174 174 174 ALA ALA E . n 
E 1 175 ASP 175 175 175 ASP ASP E . n 
E 1 176 TRP 176 176 176 TRP TRP E . n 
E 1 177 HIS 177 177 177 HIS HIS E . n 
E 1 178 LEU 178 178 178 LEU LEU E . n 
E 1 179 PRO 179 179 179 PRO PRO E . n 
E 1 180 GLU 180 180 180 GLU GLU E . n 
E 1 181 LEU 181 181 181 LEU LEU E . n 
E 1 182 TYR 182 182 182 TYR TYR E . n 
E 1 183 GLY 183 183 183 GLY GLY E . n 
E 1 184 MET 184 184 184 MET MET E . n 
E 1 185 ILE 185 185 185 ILE ILE E . n 
E 1 186 ARG 186 186 186 ARG ARG E . n 
E 1 187 HIS 187 187 187 HIS HIS E . n 
E 1 188 TYR 188 188 188 TYR TYR E . n 
E 1 189 GLN 189 189 189 GLN GLN E . n 
E 1 190 PRO 190 190 190 PRO PRO E . n 
E 1 191 ASN 191 191 191 ASN ASN E . n 
E 1 192 ALA 192 192 192 ALA ALA E . n 
E 1 193 ILE 193 193 193 ILE ILE E . n 
E 1 194 ILE 194 194 194 ILE ILE E . n 
E 1 195 VAL 195 195 195 VAL VAL E . n 
E 1 196 SER 196 196 196 SER SER E . n 
E 1 197 ASN 197 197 197 ASN ASN E . n 
E 1 198 THR 198 198 198 THR THR E . n 
E 1 199 GLY 199 199 ?   ?   ?   E . n 
E 1 200 LEU 200 200 ?   ?   ?   E . n 
E 1 201 LYS 201 201 ?   ?   ?   E . n 
E 1 202 ASN 202 202 ?   ?   ?   E . n 
E 1 203 ARG 203 203 ?   ?   ?   E . n 
E 1 204 GLY 204 204 ?   ?   ?   E . n 
E 1 205 GLN 205 205 ?   ?   ?   E . n 
E 1 206 VAL 206 206 206 VAL VAL E . n 
E 1 207 SER 207 207 207 SER SER E . n 
E 1 208 ASP 208 208 208 ASP ASP E . n 
E 1 209 PRO 209 209 209 PRO PRO E . n 
E 1 210 GLU 210 210 210 GLU GLU E . n 
E 1 211 ILE 211 211 211 ILE ILE E . n 
E 1 212 ASP 212 212 212 ASP ASP E . n 
E 1 213 VAL 213 213 213 VAL VAL E . n 
E 1 214 VAL 214 214 214 VAL VAL E . n 
E 1 215 THR 215 215 215 THR THR E . n 
E 1 216 TYR 216 216 216 TYR TYR E . n 
E 1 217 GLU 217 217 217 GLU GLU E . n 
E 1 218 ARG 218 218 218 ARG ARG E . n 
E 1 219 ARG 219 219 219 ARG ARG E . n 
E 1 220 THR 220 220 220 THR THR E . n 
E 1 221 PRO 221 221 221 PRO PRO E . n 
E 1 222 ASP 222 222 222 ASP ASP E . n 
E 1 223 GLU 223 223 223 GLU GLU E . n 
E 1 224 ILE 224 224 224 ILE ILE E . n 
E 1 225 TYR 225 225 225 TYR TYR E . n 
E 1 226 HIS 226 226 226 HIS HIS E . n 
E 1 227 GLY 227 227 227 GLY GLY E . n 
E 1 228 ALA 228 228 228 ALA ALA E . n 
E 1 229 PRO 229 229 229 PRO PRO E . n 
E 1 230 ASN 230 230 230 ASN ASN E . n 
E 1 231 GLU 231 231 231 GLU GLU E . n 
E 1 232 LYS 232 232 232 LYS LYS E . n 
E 1 233 TYR 233 233 233 TYR TYR E . n 
E 1 234 VAL 234 234 234 VAL VAL E . n 
E 1 235 ALA 235 235 235 ALA ALA E . n 
E 1 236 GLY 236 236 236 GLY GLY E . n 
E 1 237 GLU 237 237 237 GLU GLU E . n 
E 1 238 ILE 238 238 238 ILE ILE E . n 
E 1 239 SER 239 239 239 SER SER E . n 
E 1 240 ILE 240 240 240 ILE ILE E . n 
E 1 241 THR 241 241 241 THR THR E . n 
E 1 242 LEU 242 242 242 LEU LEU E . n 
E 1 243 ASN 243 243 243 ASN ASN E . n 
E 1 244 GLN 244 244 244 GLN GLN E . n 
E 1 245 HIS 245 245 245 HIS HIS E . n 
E 1 246 TRP 246 246 246 TRP TRP E . n 
E 1 247 GLY 247 247 247 GLY GLY E . n 
E 1 248 ILE 248 248 248 ILE ILE E . n 
E 1 249 ALA 249 249 249 ALA ALA E . n 
E 1 250 ALA 250 250 250 ALA ALA E . n 
E 1 251 ASN 251 251 251 ASN ASN E . n 
E 1 252 ASP 252 252 252 ASP ASP E . n 
E 1 253 LEU 253 253 253 LEU LEU E . n 
E 1 254 ASN 254 254 254 ASN ASN E . n 
E 1 255 TYR 255 255 255 TYR TYR E . n 
E 1 256 LYS 256 256 256 LYS LYS E . n 
E 1 257 SER 257 257 257 SER SER E . n 
E 1 258 PRO 258 258 258 PRO PRO E . n 
E 1 259 ALA 259 259 259 ALA ALA E . n 
E 1 260 GLU 260 260 260 GLU GLU E . n 
E 1 261 MET 261 261 261 MET MET E . n 
E 1 262 ILE 262 262 262 ILE ILE E . n 
E 1 263 GLU 263 263 263 GLU GLU E . n 
E 1 264 THR 264 264 264 THR THR E . n 
E 1 265 VAL 265 265 265 VAL VAL E . n 
E 1 266 ALA 266 266 266 ALA ALA E . n 
E 1 267 HIS 267 267 267 HIS HIS E . n 
E 1 268 ALA 268 268 268 ALA ALA E . n 
E 1 269 ARG 269 269 269 ARG ARG E . n 
E 1 270 HIS 270 270 270 HIS HIS E . n 
E 1 271 ILE 271 271 271 ILE ILE E . n 
E 1 272 GLY 272 272 272 GLY GLY E . n 
E 1 273 ALA 273 273 273 ALA ALA E . n 
E 1 274 ASN 274 274 274 ASN ASN E . n 
E 1 275 ILE 275 275 275 ILE ILE E . n 
E 1 276 LEU 276 276 276 LEU LEU E . n 
E 1 277 VAL 277 277 277 VAL VAL E . n 
E 1 278 ASN 278 278 278 ASN ASN E . n 
E 1 279 ILE 279 279 279 ILE ILE E . n 
E 1 280 GLY 280 280 280 GLY GLY E . n 
E 1 281 LEU 281 281 281 LEU LEU E . n 
E 1 282 THR 282 282 282 THR THR E . n 
E 1 283 GLY 283 283 283 GLY GLY E . n 
E 1 284 THR 284 284 284 THR THR E . n 
E 1 285 GLY 285 285 285 GLY GLY E . n 
E 1 286 ALA 286 286 286 ALA ALA E . n 
E 1 287 ILE 287 287 287 ILE ILE E . n 
E 1 288 PRO 288 288 288 PRO PRO E . n 
E 1 289 ALA 289 289 289 ALA ALA E . n 
E 1 290 ALA 290 290 290 ALA ALA E . n 
E 1 291 ALA 291 291 291 ALA ALA E . n 
E 1 292 GLN 292 292 292 GLN GLN E . n 
E 1 293 THR 293 293 293 THR THR E . n 
E 1 294 TYR 294 294 294 TYR TYR E . n 
E 1 295 MET 295 295 295 MET MET E . n 
E 1 296 HIS 296 296 296 HIS HIS E . n 
E 1 297 LEU 297 297 297 LEU LEU E . n 
E 1 298 LEU 298 298 298 LEU LEU E . n 
E 1 299 GLY 299 299 299 GLY GLY E . n 
E 1 300 ARG 300 300 300 ARG ARG E . n 
E 1 301 TRP 301 301 301 TRP TRP E . n 
E 1 302 THR 302 302 302 THR THR E . n 
E 1 303 ALA 303 303 303 ALA ALA E . n 
E 1 304 MET 304 304 304 MET MET E . n 
E 1 305 ALA 305 305 305 ALA ALA E . n 
E 1 306 ALA 306 306 306 ALA ALA E . n 
E 1 307 PRO 307 307 307 PRO PRO E . n 
E 1 308 VAL 308 308 308 VAL VAL E . n 
E 1 309 LEU 309 309 309 LEU LEU E . n 
E 1 310 TYR 310 310 310 TYR TYR E . n 
E 1 311 LYS 311 311 311 LYS LYS E . n 
E 1 312 GLY 312 312 312 GLY GLY E . n 
E 1 313 ARG 313 313 313 ARG ARG E . n 
E 1 314 PRO 314 314 314 PRO PRO E . n 
E 1 315 VAL 315 315 315 VAL VAL E . n 
E 1 316 PRO 316 316 316 PRO PRO E . n 
E 1 317 VAL 317 317 317 VAL VAL E . n 
E 1 318 THR 318 318 318 THR THR E . n 
E 1 319 SER 319 319 319 SER SER E . n 
E 1 320 ALA 320 320 320 ALA ALA E . n 
E 1 321 HIS 321 321 321 HIS HIS E . n 
E 1 322 GLY 322 322 322 GLY GLY E . n 
E 1 323 THR 323 323 323 THR THR E . n 
E 1 324 ARG 324 324 324 ARG ARG E . n 
E 1 325 ASP 325 325 325 ASP ASP E . n 
E 1 326 PHE 326 326 326 PHE PHE E . n 
E 1 327 VAL 327 327 327 VAL VAL E . n 
E 1 328 LEU 328 328 328 LEU LEU E . n 
E 1 329 HIS 329 329 329 HIS HIS E . n 
E 1 330 THR 330 330 330 THR THR E . n 
E 1 331 SER 331 331 331 SER SER E . n 
E 1 332 LYS 332 332 332 LYS LYS E . n 
E 1 333 HIS 333 333 333 HIS HIS E . n 
E 1 334 ASP 334 334 334 ASP ASP E . n 
E 1 335 PHE 335 335 335 PHE PHE E . n 
E 1 336 LEU 336 336 336 LEU LEU E . n 
E 1 337 CYS 337 337 337 CYS CYS E . n 
E 1 338 ILE 338 338 338 ILE ILE E . n 
E 1 339 LEU 339 339 339 LEU LEU E . n 
E 1 340 ASP 340 340 340 ASP ASP E . n 
E 1 341 LEU 341 341 341 LEU LEU E . n 
E 1 342 GLN 342 342 342 GLN GLN E . n 
E 1 343 VAL 343 343 343 VAL VAL E . n 
E 1 344 VAL 344 344 344 VAL VAL E . n 
E 1 345 GLY 345 345 345 GLY GLY E . n 
E 1 346 LYS 346 346 346 LYS LYS E . n 
E 1 347 ASP 347 347 347 ASP ASP E . n 
E 1 348 ASN 348 348 348 ASN ASN E . n 
E 1 349 VAL 349 349 349 VAL VAL E . n 
E 1 350 VAL 350 350 350 VAL VAL E . n 
E 1 351 LEU 351 351 351 LEU LEU E . n 
E 1 352 GLY 352 352 352 GLY GLY E . n 
E 1 353 GLY 353 353 353 GLY GLY E . n 
E 1 354 GLU 354 354 354 GLU GLU E . n 
E 1 355 GLY 355 355 355 GLY GLY E . n 
E 1 356 VAL 356 356 356 VAL VAL E . n 
E 1 357 ASN 357 357 357 ASN ASN E . n 
E 1 358 PRO 358 358 358 PRO PRO E . n 
E 1 359 ARG 359 359 359 ARG ARG E . n 
E 1 360 SER 360 360 360 SER SER E . n 
E 1 361 PHE 361 361 361 PHE PHE E . n 
E 1 362 VAL 362 362 362 VAL VAL E . n 
E 1 363 GLY 363 363 363 GLY GLY E . n 
E 1 364 ILE 364 364 364 ILE ILE E . n 
E 1 365 GLY 365 365 365 GLY GLY E . n 
E 1 366 GLN 366 366 366 GLN GLN E . n 
E 1 367 PRO 367 367 367 PRO PRO E . n 
E 1 368 ILE 368 368 368 ILE ILE E . n 
E 1 369 GLN 369 369 369 GLN GLN E . n 
E 1 370 ARG 370 370 370 ARG ARG E . n 
E 1 371 ILE 371 371 371 ILE ILE E . n 
E 1 372 HIS 372 372 372 HIS HIS E . n 
E 1 373 TRP 373 373 373 TRP TRP E . n 
E 1 374 LEU 374 374 374 LEU LEU E . n 
E 1 375 ASP 375 375 375 ASP ASP E . n 
E 1 376 ASN 376 376 376 ASN ASN E . n 
E 1 377 ASP 377 377 377 ASP ASP E . n 
E 1 378 GLU 378 378 378 GLU GLU E . n 
E 1 379 VAL 379 379 379 VAL VAL E . n 
E 1 380 LEU 380 380 380 LEU LEU E . n 
E 1 381 SER 381 381 381 SER SER E . n 
E 1 382 PHE 382 382 382 PHE PHE E . n 
E 1 383 THR 383 383 383 THR THR E . n 
E 1 384 GLN 384 384 384 GLN GLN E . n 
E 1 385 ASP 385 385 385 ASP ASP E . n 
E 1 386 LEU 386 386 386 LEU LEU E . n 
E 1 387 ASP 387 387 387 ASP ASP E . n 
E 1 388 LYS 388 388 388 LYS LYS E . n 
E 1 389 LYS 389 389 389 LYS LYS E . n 
E 1 390 VAL 390 390 390 VAL VAL E . n 
E 1 391 LEU 391 391 391 LEU LEU E . n 
E 1 392 THR 392 392 392 THR THR E . n 
E 1 393 VAL 393 393 393 VAL VAL E . n 
E 1 394 ASP 394 394 394 ASP ASP E . n 
E 1 395 ALA 395 395 395 ALA ALA E . n 
E 1 396 THR 396 396 396 THR THR E . n 
E 1 397 GLY 397 397 397 GLY GLY E . n 
E 1 398 TYR 398 398 398 TYR TYR E . n 
E 1 399 PRO 399 399 399 PRO PRO E . n 
E 1 400 TYR 400 400 400 TYR TYR E . n 
E 1 401 GLY 401 401 401 GLY GLY E . n 
E 1 402 SER 402 402 402 SER SER E . n 
E 1 403 ASP 403 403 403 ASP ASP E . n 
E 1 404 TRP 404 404 404 TRP TRP E . n 
E 1 405 VAL 405 405 405 VAL VAL E . n 
E 1 406 VAL 406 406 406 VAL VAL E . n 
E 1 407 ARG 407 407 407 ARG ARG E . n 
E 1 408 ILE 408 408 408 ILE ILE E . n 
E 1 409 ALA 409 409 409 ALA ALA E . n 
E 1 410 GLN 410 410 410 GLN GLN E . n 
E 1 411 ILE 411 411 411 ILE ILE E . n 
E 1 412 ASP 412 412 412 ASP ASP E . n 
E 1 413 TYR 413 413 413 TYR TYR E . n 
E 1 414 GLU 414 414 414 GLU GLU E . n 
F 1 1   MET 1   1   ?   ?   ?   F . n 
F 1 2   THR 2   2   2   THR THR F . n 
F 1 3   GLU 3   3   3   GLU GLU F . n 
F 1 4   PRO 4   4   4   PRO PRO F . n 
F 1 5   LEU 5   5   5   LEU LEU F . n 
F 1 6   PRO 6   6   6   PRO PRO F . n 
F 1 7   ARG 7   7   7   ARG ARG F . n 
F 1 8   ILE 8   8   8   ILE ILE F . n 
F 1 9   GLN 9   9   9   GLN GLN F . n 
F 1 10  HIS 10  10  10  HIS HIS F . n 
F 1 11  TYR 11  11  11  TYR TYR F . n 
F 1 12  GLU 12  12  12  GLU GLU F . n 
F 1 13  ASP 13  13  13  ASP ASP F . n 
F 1 14  LEU 14  14  14  LEU LEU F . n 
F 1 15  GLY 15  15  15  GLY GLY F . n 
F 1 16  LEU 16  16  16  LEU LEU F . n 
F 1 17  GLY 17  17  17  GLY GLY F . n 
F 1 18  LEU 18  18  18  LEU LEU F . n 
F 1 19  PHE 19  19  19  PHE PHE F . n 
F 1 20  ILE 20  20  20  ILE ILE F . n 
F 1 21  HIS 21  21  21  HIS HIS F . n 
F 1 22  TRP 22  22  22  TRP TRP F . n 
F 1 23  GLY 23  23  23  GLY GLY F . n 
F 1 24  LEU 24  24  24  LEU LEU F . n 
F 1 25  TYR 25  25  25  TYR TYR F . n 
F 1 26  SER 26  26  26  SER SER F . n 
F 1 27  GLN 27  27  27  GLN GLN F . n 
F 1 28  MET 28  28  28  MET MET F . n 
F 1 29  ALA 29  29  29  ALA ALA F . n 
F 1 30  VAL 30  30  30  VAL VAL F . n 
F 1 31  GLY 31  31  31  GLY GLY F . n 
F 1 32  GLU 32  32  32  GLU GLU F . n 
F 1 33  TRP 33  33  33  TRP TRP F . n 
F 1 34  THR 34  34  34  THR THR F . n 
F 1 35  GLU 35  35  35  GLU GLU F . n 
F 1 36  LEU 36  36  36  LEU LEU F . n 
F 1 37  ILE 37  37  37  ILE ILE F . n 
F 1 38  HIS 38  38  38  HIS HIS F . n 
F 1 39  HIS 39  39  39  HIS HIS F . n 
F 1 40  ARG 40  40  40  ARG ARG F . n 
F 1 41  ASN 41  41  41  ASN ASN F . n 
F 1 42  GLN 42  42  42  GLN GLN F . n 
F 1 43  HIS 43  43  43  HIS HIS F . n 
F 1 44  ASP 44  44  44  ASP ASP F . n 
F 1 45  TYR 45  45  45  TYR TYR F . n 
F 1 46  GLU 46  46  46  GLU GLU F . n 
F 1 47  GLN 47  47  47  GLN GLN F . n 
F 1 48  LEU 48  48  48  LEU LEU F . n 
F 1 49  ILE 49  49  49  ILE ILE F . n 
F 1 50  LYS 50  50  50  LYS LYS F . n 
F 1 51  THR 51  51  51  THR THR F . n 
F 1 52  PHE 52  52  52  PHE PHE F . n 
F 1 53  THR 53  53  53  THR THR F . n 
F 1 54  ALA 54  54  54  ALA ALA F . n 
F 1 55  ALA 55  55  55  ALA ALA F . n 
F 1 56  GLN 56  56  56  GLN GLN F . n 
F 1 57  PHE 57  57  57  PHE PHE F . n 
F 1 58  ASP 58  58  58  ASP ASP F . n 
F 1 59  ALA 59  59  59  ALA ALA F . n 
F 1 60  LYS 60  60  60  LYS LYS F . n 
F 1 61  LYS 61  61  61  LYS LYS F . n 
F 1 62  ILE 62  62  62  ILE ILE F . n 
F 1 63  ALA 63  63  63  ALA ALA F . n 
F 1 64  HIS 64  64  64  HIS HIS F . n 
F 1 65  ALA 65  65  65  ALA ALA F . n 
F 1 66  ALA 66  66  66  ALA ALA F . n 
F 1 67  LYS 67  67  67  LYS LYS F . n 
F 1 68  ALA 68  68  68  ALA ALA F . n 
F 1 69  VAL 69  69  69  VAL VAL F . n 
F 1 70  GLY 70  70  70  GLY GLY F . n 
F 1 71  ALA 71  71  71  ALA ALA F . n 
F 1 72  LYS 72  72  72  LYS LYS F . n 
F 1 73  TYR 73  73  73  TYR TYR F . n 
F 1 74  ILE 74  74  74  ILE ILE F . n 
F 1 75  VAL 75  75  75  VAL VAL F . n 
F 1 76  LEU 76  76  76  LEU LEU F . n 
F 1 77  THR 77  77  77  THR THR F . n 
F 1 78  THR 78  78  78  THR THR F . n 
F 1 79  LYS 79  79  79  LYS LYS F . n 
F 1 80  HIS 80  80  80  HIS HIS F . n 
F 1 81  HIS 81  81  81  HIS HIS F . n 
F 1 82  GLU 82  82  82  GLU GLU F . n 
F 1 83  GLY 83  83  83  GLY GLY F . n 
F 1 84  PHE 84  84  84  PHE PHE F . n 
F 1 85  PHE 85  85  85  PHE PHE F . n 
F 1 86  LEU 86  86  86  LEU LEU F . n 
F 1 87  TYR 87  87  87  TYR TYR F . n 
F 1 88  ASP 88  88  88  ASP ASP F . n 
F 1 89  THR 89  89  89  THR THR F . n 
F 1 90  LYS 90  90  90  LYS LYS F . n 
F 1 91  GLY 91  91  91  GLY GLY F . n 
F 1 92  LEU 92  92  92  LEU LEU F . n 
F 1 93  SER 93  93  93  SER SER F . n 
F 1 94  ASP 94  94  94  ASP ASP F . n 
F 1 95  PHE 95  95  95  PHE PHE F . n 
F 1 96  ASP 96  96  96  ASP ASP F . n 
F 1 97  VAL 97  97  97  VAL VAL F . n 
F 1 98  MET 98  98  98  MET MET F . n 
F 1 99  HIS 99  99  99  HIS HIS F . n 
F 1 100 ALA 100 100 100 ALA ALA F . n 
F 1 101 PRO 101 101 101 PRO PRO F . n 
F 1 102 ALA 102 102 102 ALA ALA F . n 
F 1 103 ARG 103 103 103 ARG ARG F . n 
F 1 104 ARG 104 104 104 ARG ARG F . n 
F 1 105 ASP 105 105 105 ASP ASP F . n 
F 1 106 LEU 106 106 106 LEU LEU F . n 
F 1 107 ILE 107 107 107 ILE ILE F . n 
F 1 108 ALA 108 108 108 ALA ALA F . n 
F 1 109 GLU 109 109 109 GLU GLU F . n 
F 1 110 PHE 110 110 110 PHE PHE F . n 
F 1 111 VAL 111 111 111 VAL VAL F . n 
F 1 112 ALA 112 112 112 ALA ALA F . n 
F 1 113 ALA 113 113 113 ALA ALA F . n 
F 1 114 CYS 114 114 114 CYS CYS F . n 
F 1 115 ARG 115 115 115 ARG ARG F . n 
F 1 116 GLU 116 116 116 GLU GLU F . n 
F 1 117 GLU 117 117 117 GLU GLU F . n 
F 1 118 ASP 118 118 118 ASP ASP F . n 
F 1 119 LEU 119 119 119 LEU LEU F . n 
F 1 120 LEU 120 120 120 LEU LEU F . n 
F 1 121 PRO 121 121 121 PRO PRO F . n 
F 1 122 PHE 122 122 122 PHE PHE F . n 
F 1 123 PHE 123 123 123 PHE PHE F . n 
F 1 124 TYR 124 124 124 TYR TYR F . n 
F 1 125 MET 125 125 125 MET MET F . n 
F 1 126 ALA 126 126 126 ALA ALA F . n 
F 1 127 THR 127 127 127 THR THR F . n 
F 1 128 TYR 128 128 128 TYR TYR F . n 
F 1 129 ASP 129 129 129 ASP ASP F . n 
F 1 130 TRP 130 130 130 TRP TRP F . n 
F 1 131 HIS 131 131 131 HIS HIS F . n 
F 1 132 THR 132 132 132 THR THR F . n 
F 1 133 PRO 133 133 133 PRO PRO F . n 
F 1 134 LEU 134 134 134 LEU LEU F . n 
F 1 135 TYR 135 135 135 TYR TYR F . n 
F 1 136 ASP 136 136 136 ASP ASP F . n 
F 1 137 ASP 137 137 137 ASP ASP F . n 
F 1 138 ASP 138 138 138 ASP ASP F . n 
F 1 139 PHE 139 139 139 PHE PHE F . n 
F 1 140 PRO 140 140 140 PRO PRO F . n 
F 1 141 ALA 141 141 141 ALA ALA F . n 
F 1 142 TYR 142 142 142 TYR TYR F . n 
F 1 143 LEU 143 143 143 LEU LEU F . n 
F 1 144 THR 144 144 144 THR THR F . n 
F 1 145 TYR 145 145 145 TYR TYR F . n 
F 1 146 LEU 146 146 146 LEU LEU F . n 
F 1 147 GLN 147 147 147 GLN GLN F . n 
F 1 148 LYS 148 148 148 LYS LYS F . n 
F 1 149 SER 149 149 149 SER SER F . n 
F 1 150 VAL 150 150 150 VAL VAL F . n 
F 1 151 GLU 151 151 151 GLU GLU F . n 
F 1 152 VAL 152 152 152 VAL VAL F . n 
F 1 153 LEU 153 153 153 LEU LEU F . n 
F 1 154 CYS 154 154 154 CYS CYS F . n 
F 1 155 ARG 155 155 155 ARG ARG F . n 
F 1 156 ASN 156 156 156 ASN ASN F . n 
F 1 157 TYR 157 157 157 TYR TYR F . n 
F 1 158 GLY 158 158 158 GLY GLY F . n 
F 1 159 PRO 159 159 159 PRO PRO F . n 
F 1 160 VAL 160 160 160 VAL VAL F . n 
F 1 161 GLY 161 161 161 GLY GLY F . n 
F 1 162 GLY 162 162 162 GLY GLY F . n 
F 1 163 PHE 163 163 163 PHE PHE F . n 
F 1 164 TRP 164 164 164 TRP TRP F . n 
F 1 165 PHE 165 165 165 PHE PHE F . n 
F 1 166 ASP 166 166 166 ASP ASP F . n 
F 1 167 GLY 167 167 167 GLY GLY F . n 
F 1 168 ASN 168 168 168 ASN ASN F . n 
F 1 169 TRP 169 169 169 TRP TRP F . n 
F 1 170 ASN 170 170 170 ASN ASN F . n 
F 1 171 LYS 171 171 171 LYS LYS F . n 
F 1 172 LYS 172 172 172 LYS LYS F . n 
F 1 173 ASP 173 173 173 ASP ASP F . n 
F 1 174 ALA 174 174 174 ALA ALA F . n 
F 1 175 ASP 175 175 175 ASP ASP F . n 
F 1 176 TRP 176 176 176 TRP TRP F . n 
F 1 177 HIS 177 177 177 HIS HIS F . n 
F 1 178 LEU 178 178 178 LEU LEU F . n 
F 1 179 PRO 179 179 179 PRO PRO F . n 
F 1 180 GLU 180 180 180 GLU GLU F . n 
F 1 181 LEU 181 181 181 LEU LEU F . n 
F 1 182 TYR 182 182 182 TYR TYR F . n 
F 1 183 GLY 183 183 183 GLY GLY F . n 
F 1 184 MET 184 184 184 MET MET F . n 
F 1 185 ILE 185 185 185 ILE ILE F . n 
F 1 186 ARG 186 186 186 ARG ARG F . n 
F 1 187 HIS 187 187 187 HIS HIS F . n 
F 1 188 TYR 188 188 188 TYR TYR F . n 
F 1 189 GLN 189 189 189 GLN GLN F . n 
F 1 190 PRO 190 190 190 PRO PRO F . n 
F 1 191 ASN 191 191 191 ASN ASN F . n 
F 1 192 ALA 192 192 192 ALA ALA F . n 
F 1 193 ILE 193 193 193 ILE ILE F . n 
F 1 194 ILE 194 194 194 ILE ILE F . n 
F 1 195 VAL 195 195 195 VAL VAL F . n 
F 1 196 SER 196 196 196 SER SER F . n 
F 1 197 ASN 197 197 197 ASN ASN F . n 
F 1 198 THR 198 198 198 THR THR F . n 
F 1 199 GLY 199 199 ?   ?   ?   F . n 
F 1 200 LEU 200 200 ?   ?   ?   F . n 
F 1 201 LYS 201 201 ?   ?   ?   F . n 
F 1 202 ASN 202 202 ?   ?   ?   F . n 
F 1 203 ARG 203 203 ?   ?   ?   F . n 
F 1 204 GLY 204 204 ?   ?   ?   F . n 
F 1 205 GLN 205 205 205 GLN GLN F . n 
F 1 206 VAL 206 206 206 VAL VAL F . n 
F 1 207 SER 207 207 207 SER SER F . n 
F 1 208 ASP 208 208 208 ASP ASP F . n 
F 1 209 PRO 209 209 209 PRO PRO F . n 
F 1 210 GLU 210 210 210 GLU GLU F . n 
F 1 211 ILE 211 211 211 ILE ILE F . n 
F 1 212 ASP 212 212 212 ASP ASP F . n 
F 1 213 VAL 213 213 213 VAL VAL F . n 
F 1 214 VAL 214 214 214 VAL VAL F . n 
F 1 215 THR 215 215 215 THR THR F . n 
F 1 216 TYR 216 216 216 TYR TYR F . n 
F 1 217 GLU 217 217 217 GLU GLU F . n 
F 1 218 ARG 218 218 218 ARG ARG F . n 
F 1 219 ARG 219 219 219 ARG ARG F . n 
F 1 220 THR 220 220 220 THR THR F . n 
F 1 221 PRO 221 221 221 PRO PRO F . n 
F 1 222 ASP 222 222 222 ASP ASP F . n 
F 1 223 GLU 223 223 223 GLU GLU F . n 
F 1 224 ILE 224 224 224 ILE ILE F . n 
F 1 225 TYR 225 225 225 TYR TYR F . n 
F 1 226 HIS 226 226 226 HIS HIS F . n 
F 1 227 GLY 227 227 227 GLY GLY F . n 
F 1 228 ALA 228 228 228 ALA ALA F . n 
F 1 229 PRO 229 229 229 PRO PRO F . n 
F 1 230 ASN 230 230 230 ASN ASN F . n 
F 1 231 GLU 231 231 231 GLU GLU F . n 
F 1 232 LYS 232 232 232 LYS LYS F . n 
F 1 233 TYR 233 233 233 TYR TYR F . n 
F 1 234 VAL 234 234 234 VAL VAL F . n 
F 1 235 ALA 235 235 235 ALA ALA F . n 
F 1 236 GLY 236 236 236 GLY GLY F . n 
F 1 237 GLU 237 237 237 GLU GLU F . n 
F 1 238 ILE 238 238 238 ILE ILE F . n 
F 1 239 SER 239 239 239 SER SER F . n 
F 1 240 ILE 240 240 240 ILE ILE F . n 
F 1 241 THR 241 241 241 THR THR F . n 
F 1 242 LEU 242 242 242 LEU LEU F . n 
F 1 243 ASN 243 243 243 ASN ASN F . n 
F 1 244 GLN 244 244 244 GLN GLN F . n 
F 1 245 HIS 245 245 245 HIS HIS F . n 
F 1 246 TRP 246 246 246 TRP TRP F . n 
F 1 247 GLY 247 247 247 GLY GLY F . n 
F 1 248 ILE 248 248 248 ILE ILE F . n 
F 1 249 ALA 249 249 249 ALA ALA F . n 
F 1 250 ALA 250 250 250 ALA ALA F . n 
F 1 251 ASN 251 251 251 ASN ASN F . n 
F 1 252 ASP 252 252 252 ASP ASP F . n 
F 1 253 LEU 253 253 253 LEU LEU F . n 
F 1 254 ASN 254 254 254 ASN ASN F . n 
F 1 255 TYR 255 255 255 TYR TYR F . n 
F 1 256 LYS 256 256 256 LYS LYS F . n 
F 1 257 SER 257 257 257 SER SER F . n 
F 1 258 PRO 258 258 258 PRO PRO F . n 
F 1 259 ALA 259 259 259 ALA ALA F . n 
F 1 260 GLU 260 260 260 GLU GLU F . n 
F 1 261 MET 261 261 261 MET MET F . n 
F 1 262 ILE 262 262 262 ILE ILE F . n 
F 1 263 GLU 263 263 263 GLU GLU F . n 
F 1 264 THR 264 264 264 THR THR F . n 
F 1 265 VAL 265 265 265 VAL VAL F . n 
F 1 266 ALA 266 266 266 ALA ALA F . n 
F 1 267 HIS 267 267 267 HIS HIS F . n 
F 1 268 ALA 268 268 268 ALA ALA F . n 
F 1 269 ARG 269 269 269 ARG ARG F . n 
F 1 270 HIS 270 270 270 HIS HIS F . n 
F 1 271 ILE 271 271 271 ILE ILE F . n 
F 1 272 GLY 272 272 272 GLY GLY F . n 
F 1 273 ALA 273 273 273 ALA ALA F . n 
F 1 274 ASN 274 274 274 ASN ASN F . n 
F 1 275 ILE 275 275 275 ILE ILE F . n 
F 1 276 LEU 276 276 276 LEU LEU F . n 
F 1 277 VAL 277 277 277 VAL VAL F . n 
F 1 278 ASN 278 278 278 ASN ASN F . n 
F 1 279 ILE 279 279 279 ILE ILE F . n 
F 1 280 GLY 280 280 280 GLY GLY F . n 
F 1 281 LEU 281 281 281 LEU LEU F . n 
F 1 282 THR 282 282 282 THR THR F . n 
F 1 283 GLY 283 283 283 GLY GLY F . n 
F 1 284 THR 284 284 284 THR THR F . n 
F 1 285 GLY 285 285 285 GLY GLY F . n 
F 1 286 ALA 286 286 286 ALA ALA F . n 
F 1 287 ILE 287 287 287 ILE ILE F . n 
F 1 288 PRO 288 288 288 PRO PRO F . n 
F 1 289 ALA 289 289 289 ALA ALA F . n 
F 1 290 ALA 290 290 290 ALA ALA F . n 
F 1 291 ALA 291 291 291 ALA ALA F . n 
F 1 292 GLN 292 292 292 GLN GLN F . n 
F 1 293 THR 293 293 293 THR THR F . n 
F 1 294 TYR 294 294 294 TYR TYR F . n 
F 1 295 MET 295 295 295 MET MET F . n 
F 1 296 HIS 296 296 296 HIS HIS F . n 
F 1 297 LEU 297 297 297 LEU LEU F . n 
F 1 298 LEU 298 298 298 LEU LEU F . n 
F 1 299 GLY 299 299 299 GLY GLY F . n 
F 1 300 ARG 300 300 300 ARG ARG F . n 
F 1 301 TRP 301 301 301 TRP TRP F . n 
F 1 302 THR 302 302 302 THR THR F . n 
F 1 303 ALA 303 303 303 ALA ALA F . n 
F 1 304 MET 304 304 304 MET MET F . n 
F 1 305 ALA 305 305 305 ALA ALA F . n 
F 1 306 ALA 306 306 306 ALA ALA F . n 
F 1 307 PRO 307 307 307 PRO PRO F . n 
F 1 308 VAL 308 308 308 VAL VAL F . n 
F 1 309 LEU 309 309 309 LEU LEU F . n 
F 1 310 TYR 310 310 310 TYR TYR F . n 
F 1 311 LYS 311 311 311 LYS LYS F . n 
F 1 312 GLY 312 312 312 GLY GLY F . n 
F 1 313 ARG 313 313 313 ARG ARG F . n 
F 1 314 PRO 314 314 314 PRO PRO F . n 
F 1 315 VAL 315 315 315 VAL VAL F . n 
F 1 316 PRO 316 316 316 PRO PRO F . n 
F 1 317 VAL 317 317 317 VAL VAL F . n 
F 1 318 THR 318 318 318 THR THR F . n 
F 1 319 SER 319 319 319 SER SER F . n 
F 1 320 ALA 320 320 320 ALA ALA F . n 
F 1 321 HIS 321 321 321 HIS HIS F . n 
F 1 322 GLY 322 322 322 GLY GLY F . n 
F 1 323 THR 323 323 323 THR THR F . n 
F 1 324 ARG 324 324 324 ARG ARG F . n 
F 1 325 ASP 325 325 325 ASP ASP F . n 
F 1 326 PHE 326 326 326 PHE PHE F . n 
F 1 327 VAL 327 327 327 VAL VAL F . n 
F 1 328 LEU 328 328 328 LEU LEU F . n 
F 1 329 HIS 329 329 329 HIS HIS F . n 
F 1 330 THR 330 330 330 THR THR F . n 
F 1 331 SER 331 331 331 SER SER F . n 
F 1 332 LYS 332 332 332 LYS LYS F . n 
F 1 333 HIS 333 333 333 HIS HIS F . n 
F 1 334 ASP 334 334 334 ASP ASP F . n 
F 1 335 PHE 335 335 335 PHE PHE F . n 
F 1 336 LEU 336 336 336 LEU LEU F . n 
F 1 337 CYS 337 337 337 CYS CYS F . n 
F 1 338 ILE 338 338 338 ILE ILE F . n 
F 1 339 LEU 339 339 339 LEU LEU F . n 
F 1 340 ASP 340 340 340 ASP ASP F . n 
F 1 341 LEU 341 341 341 LEU LEU F . n 
F 1 342 GLN 342 342 342 GLN GLN F . n 
F 1 343 VAL 343 343 343 VAL VAL F . n 
F 1 344 VAL 344 344 344 VAL VAL F . n 
F 1 345 GLY 345 345 345 GLY GLY F . n 
F 1 346 LYS 346 346 346 LYS LYS F . n 
F 1 347 ASP 347 347 347 ASP ASP F . n 
F 1 348 ASN 348 348 348 ASN ASN F . n 
F 1 349 VAL 349 349 349 VAL VAL F . n 
F 1 350 VAL 350 350 350 VAL VAL F . n 
F 1 351 LEU 351 351 351 LEU LEU F . n 
F 1 352 GLY 352 352 352 GLY GLY F . n 
F 1 353 GLY 353 353 353 GLY GLY F . n 
F 1 354 GLU 354 354 354 GLU GLU F . n 
F 1 355 GLY 355 355 355 GLY GLY F . n 
F 1 356 VAL 356 356 356 VAL VAL F . n 
F 1 357 ASN 357 357 357 ASN ASN F . n 
F 1 358 PRO 358 358 358 PRO PRO F . n 
F 1 359 ARG 359 359 359 ARG ARG F . n 
F 1 360 SER 360 360 360 SER SER F . n 
F 1 361 PHE 361 361 361 PHE PHE F . n 
F 1 362 VAL 362 362 362 VAL VAL F . n 
F 1 363 GLY 363 363 363 GLY GLY F . n 
F 1 364 ILE 364 364 364 ILE ILE F . n 
F 1 365 GLY 365 365 365 GLY GLY F . n 
F 1 366 GLN 366 366 366 GLN GLN F . n 
F 1 367 PRO 367 367 367 PRO PRO F . n 
F 1 368 ILE 368 368 368 ILE ILE F . n 
F 1 369 GLN 369 369 369 GLN GLN F . n 
F 1 370 ARG 370 370 370 ARG ARG F . n 
F 1 371 ILE 371 371 371 ILE ILE F . n 
F 1 372 HIS 372 372 372 HIS HIS F . n 
F 1 373 TRP 373 373 373 TRP TRP F . n 
F 1 374 LEU 374 374 374 LEU LEU F . n 
F 1 375 ASP 375 375 375 ASP ASP F . n 
F 1 376 ASN 376 376 376 ASN ASN F . n 
F 1 377 ASP 377 377 377 ASP ASP F . n 
F 1 378 GLU 378 378 378 GLU GLU F . n 
F 1 379 VAL 379 379 379 VAL VAL F . n 
F 1 380 LEU 380 380 380 LEU LEU F . n 
F 1 381 SER 381 381 381 SER SER F . n 
F 1 382 PHE 382 382 382 PHE PHE F . n 
F 1 383 THR 383 383 383 THR THR F . n 
F 1 384 GLN 384 384 384 GLN GLN F . n 
F 1 385 ASP 385 385 385 ASP ASP F . n 
F 1 386 LEU 386 386 386 LEU LEU F . n 
F 1 387 ASP 387 387 387 ASP ASP F . n 
F 1 388 LYS 388 388 388 LYS LYS F . n 
F 1 389 LYS 389 389 389 LYS LYS F . n 
F 1 390 VAL 390 390 390 VAL VAL F . n 
F 1 391 LEU 391 391 391 LEU LEU F . n 
F 1 392 THR 392 392 392 THR THR F . n 
F 1 393 VAL 393 393 393 VAL VAL F . n 
F 1 394 ASP 394 394 394 ASP ASP F . n 
F 1 395 ALA 395 395 395 ALA ALA F . n 
F 1 396 THR 396 396 396 THR THR F . n 
F 1 397 GLY 397 397 397 GLY GLY F . n 
F 1 398 TYR 398 398 398 TYR TYR F . n 
F 1 399 PRO 399 399 399 PRO PRO F . n 
F 1 400 TYR 400 400 400 TYR TYR F . n 
F 1 401 GLY 401 401 401 GLY GLY F . n 
F 1 402 SER 402 402 402 SER SER F . n 
F 1 403 ASP 403 403 403 ASP ASP F . n 
F 1 404 TRP 404 404 404 TRP TRP F . n 
F 1 405 VAL 405 405 405 VAL VAL F . n 
F 1 406 VAL 406 406 406 VAL VAL F . n 
F 1 407 ARG 407 407 407 ARG ARG F . n 
F 1 408 ILE 408 408 408 ILE ILE F . n 
F 1 409 ALA 409 409 409 ALA ALA F . n 
F 1 410 GLN 410 410 410 GLN GLN F . n 
F 1 411 ILE 411 411 411 ILE ILE F . n 
F 1 412 ASP 412 412 412 ASP ASP F . n 
F 1 413 TYR 413 413 413 TYR TYR F . n 
F 1 414 GLU 414 414 414 GLU GLU F . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        JFZ 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   JFZ 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 2 JFZ 1   1001 1001 JFZ JFZ A . 
H 2 JFZ 1   1001 1001 JFZ JFZ B . 
I 2 JFZ 1   1001 1001 JFZ JFZ C . 
J 2 JFZ 1   1001 1001 JFZ JFZ D . 
K 2 JFZ 1   1001 1001 JFZ JFZ E . 
L 2 JFZ 1   1001 1001 JFZ JFZ F . 
M 3 HOH 1   1101 773  HOH HOH A . 
M 3 HOH 2   1102 19   HOH HOH A . 
M 3 HOH 3   1103 1036 HOH HOH A . 
M 3 HOH 4   1104 832  HOH HOH A . 
M 3 HOH 5   1105 446  HOH HOH A . 
M 3 HOH 6   1106 841  HOH HOH A . 
M 3 HOH 7   1107 307  HOH HOH A . 
M 3 HOH 8   1108 1085 HOH HOH A . 
M 3 HOH 9   1109 745  HOH HOH A . 
M 3 HOH 10  1110 27   HOH HOH A . 
M 3 HOH 11  1111 794  HOH HOH A . 
M 3 HOH 12  1112 842  HOH HOH A . 
M 3 HOH 13  1113 825  HOH HOH A . 
M 3 HOH 14  1114 808  HOH HOH A . 
M 3 HOH 15  1115 836  HOH HOH A . 
M 3 HOH 16  1116 741  HOH HOH A . 
M 3 HOH 17  1117 826  HOH HOH A . 
M 3 HOH 18  1118 51   HOH HOH A . 
M 3 HOH 19  1119 309  HOH HOH A . 
M 3 HOH 20  1120 687  HOH HOH A . 
M 3 HOH 21  1121 49   HOH HOH A . 
M 3 HOH 22  1122 1117 HOH HOH A . 
M 3 HOH 23  1123 1037 HOH HOH A . 
M 3 HOH 24  1124 63   HOH HOH A . 
M 3 HOH 25  1125 586  HOH HOH A . 
M 3 HOH 26  1126 3    HOH HOH A . 
M 3 HOH 27  1127 684  HOH HOH A . 
M 3 HOH 28  1128 830  HOH HOH A . 
M 3 HOH 29  1129 430  HOH HOH A . 
M 3 HOH 30  1130 812  HOH HOH A . 
M 3 HOH 31  1131 813  HOH HOH A . 
M 3 HOH 32  1132 829  HOH HOH A . 
M 3 HOH 33  1133 1080 HOH HOH A . 
M 3 HOH 34  1134 53   HOH HOH A . 
M 3 HOH 35  1135 1086 HOH HOH A . 
M 3 HOH 36  1136 15   HOH HOH A . 
M 3 HOH 37  1137 726  HOH HOH A . 
M 3 HOH 38  1138 677  HOH HOH A . 
M 3 HOH 39  1139 700  HOH HOH A . 
M 3 HOH 40  1140 48   HOH HOH A . 
M 3 HOH 41  1141 166  HOH HOH A . 
M 3 HOH 42  1142 57   HOH HOH A . 
M 3 HOH 43  1143 191  HOH HOH A . 
M 3 HOH 44  1144 1087 HOH HOH A . 
M 3 HOH 45  1145 672  HOH HOH A . 
M 3 HOH 46  1146 760  HOH HOH A . 
M 3 HOH 47  1147 722  HOH HOH A . 
M 3 HOH 48  1148 674  HOH HOH A . 
M 3 HOH 49  1149 1014 HOH HOH A . 
M 3 HOH 50  1150 783  HOH HOH A . 
M 3 HOH 51  1151 820  HOH HOH A . 
M 3 HOH 52  1152 271  HOH HOH A . 
M 3 HOH 53  1153 772  HOH HOH A . 
M 3 HOH 54  1154 437  HOH HOH A . 
M 3 HOH 55  1155 637  HOH HOH A . 
M 3 HOH 56  1156 59   HOH HOH A . 
M 3 HOH 57  1157 688  HOH HOH A . 
M 3 HOH 58  1158 163  HOH HOH A . 
M 3 HOH 59  1159 549  HOH HOH A . 
M 3 HOH 60  1160 106  HOH HOH A . 
M 3 HOH 61  1161 720  HOH HOH A . 
M 3 HOH 62  1162 839  HOH HOH A . 
M 3 HOH 63  1163 670  HOH HOH A . 
M 3 HOH 64  1164 465  HOH HOH A . 
M 3 HOH 65  1165 269  HOH HOH A . 
M 3 HOH 66  1166 1020 HOH HOH A . 
M 3 HOH 67  1167 52   HOH HOH A . 
M 3 HOH 68  1168 445  HOH HOH A . 
M 3 HOH 69  1169 845  HOH HOH A . 
M 3 HOH 70  1170 409  HOH HOH A . 
M 3 HOH 71  1171 16   HOH HOH A . 
M 3 HOH 72  1172 274  HOH HOH A . 
M 3 HOH 73  1173 840  HOH HOH A . 
M 3 HOH 74  1174 807  HOH HOH A . 
M 3 HOH 75  1175 843  HOH HOH A . 
M 3 HOH 76  1176 838  HOH HOH A . 
M 3 HOH 77  1177 62   HOH HOH A . 
M 3 HOH 78  1178 668  HOH HOH A . 
M 3 HOH 79  1179 305  HOH HOH A . 
M 3 HOH 80  1180 455  HOH HOH A . 
M 3 HOH 81  1181 786  HOH HOH A . 
M 3 HOH 82  1182 9    HOH HOH A . 
M 3 HOH 83  1183 270  HOH HOH A . 
M 3 HOH 84  1184 806  HOH HOH A . 
M 3 HOH 85  1185 425  HOH HOH A . 
M 3 HOH 86  1186 54   HOH HOH A . 
M 3 HOH 87  1187 680  HOH HOH A . 
M 3 HOH 88  1188 311  HOH HOH A . 
M 3 HOH 89  1189 635  HOH HOH A . 
M 3 HOH 90  1190 164  HOH HOH A . 
M 3 HOH 91  1191 679  HOH HOH A . 
M 3 HOH 92  1192 8    HOH HOH A . 
M 3 HOH 93  1193 847  HOH HOH A . 
M 3 HOH 94  1194 563  HOH HOH A . 
M 3 HOH 95  1195 312  HOH HOH A . 
M 3 HOH 96  1196 719  HOH HOH A . 
M 3 HOH 97  1197 1082 HOH HOH A . 
M 3 HOH 98  1198 619  HOH HOH A . 
M 3 HOH 99  1199 827  HOH HOH A . 
M 3 HOH 100 1200 484  HOH HOH A . 
M 3 HOH 101 1201 440  HOH HOH A . 
M 3 HOH 102 1202 390  HOH HOH A . 
M 3 HOH 103 1203 172  HOH HOH A . 
M 3 HOH 104 1204 817  HOH HOH A . 
M 3 HOH 105 1205 17   HOH HOH A . 
M 3 HOH 106 1206 834  HOH HOH A . 
M 3 HOH 107 1207 314  HOH HOH A . 
M 3 HOH 108 1208 50   HOH HOH A . 
M 3 HOH 109 1209 815  HOH HOH A . 
M 3 HOH 110 1210 1083 HOH HOH A . 
M 3 HOH 111 1211 1063 HOH HOH A . 
M 3 HOH 112 1212 516  HOH HOH A . 
M 3 HOH 113 1213 1026 HOH HOH A . 
M 3 HOH 114 1214 810  HOH HOH A . 
M 3 HOH 115 1215 14   HOH HOH A . 
M 3 HOH 116 1216 1047 HOH HOH A . 
M 3 HOH 117 1217 691  HOH HOH A . 
M 3 HOH 118 1218 529  HOH HOH A . 
M 3 HOH 119 1219 824  HOH HOH A . 
M 3 HOH 120 1220 855  HOH HOH A . 
M 3 HOH 121 1221 47   HOH HOH A . 
M 3 HOH 122 1222 190  HOH HOH A . 
M 3 HOH 123 1223 620  HOH HOH A . 
M 3 HOH 124 1224 171  HOH HOH A . 
M 3 HOH 125 1225 1023 HOH HOH A . 
M 3 HOH 126 1226 336  HOH HOH A . 
M 3 HOH 127 1227 682  HOH HOH A . 
M 3 HOH 128 1228 56   HOH HOH A . 
M 3 HOH 129 1229 856  HOH HOH A . 
M 3 HOH 130 1230 822  HOH HOH A . 
M 3 HOH 131 1231 578  HOH HOH A . 
M 3 HOH 132 1232 1038 HOH HOH A . 
M 3 HOH 133 1233 436  HOH HOH A . 
M 3 HOH 134 1234 844  HOH HOH A . 
M 3 HOH 135 1235 456  HOH HOH A . 
M 3 HOH 136 1236 548  HOH HOH A . 
M 3 HOH 137 1237 398  HOH HOH A . 
M 3 HOH 138 1238 406  HOH HOH A . 
M 3 HOH 139 1239 809  HOH HOH A . 
M 3 HOH 140 1240 167  HOH HOH A . 
M 3 HOH 141 1241 582  HOH HOH A . 
M 3 HOH 142 1242 526  HOH HOH A . 
M 3 HOH 143 1243 310  HOH HOH A . 
M 3 HOH 144 1244 805  HOH HOH A . 
M 3 HOH 145 1245 18   HOH HOH A . 
M 3 HOH 146 1246 828  HOH HOH A . 
M 3 HOH 147 1247 103  HOH HOH A . 
M 3 HOH 148 1248 1024 HOH HOH A . 
M 3 HOH 149 1249 835  HOH HOH A . 
M 3 HOH 150 1250 469  HOH HOH A . 
M 3 HOH 151 1251 816  HOH HOH A . 
M 3 HOH 152 1252 811  HOH HOH A . 
M 3 HOH 153 1253 833  HOH HOH A . 
M 3 HOH 154 1254 789  HOH HOH A . 
M 3 HOH 155 1255 2    HOH HOH A . 
M 3 HOH 156 1256 793  HOH HOH A . 
M 3 HOH 157 1257 6    HOH HOH A . 
M 3 HOH 158 1258 1019 HOH HOH A . 
M 3 HOH 159 1259 60   HOH HOH A . 
M 3 HOH 160 1260 303  HOH HOH A . 
M 3 HOH 161 1261 779  HOH HOH A . 
M 3 HOH 162 1262 273  HOH HOH A . 
M 3 HOH 163 1263 1116 HOH HOH A . 
M 3 HOH 164 1264 306  HOH HOH A . 
M 3 HOH 165 1265 837  HOH HOH A . 
M 3 HOH 166 1266 846  HOH HOH A . 
M 3 HOH 167 1267 1048 HOH HOH A . 
M 3 HOH 168 1268 692  HOH HOH A . 
M 3 HOH 169 1269 275  HOH HOH A . 
M 3 HOH 170 1270 1021 HOH HOH A . 
M 3 HOH 171 1271 543  HOH HOH A . 
M 3 HOH 172 1272 515  HOH HOH A . 
M 3 HOH 173 1273 264  HOH HOH A . 
M 3 HOH 174 1274 500  HOH HOH A . 
M 3 HOH 175 1275 823  HOH HOH A . 
M 3 HOH 176 1276 567  HOH HOH A . 
M 3 HOH 177 1277 272  HOH HOH A . 
M 3 HOH 178 1278 742  HOH HOH A . 
M 3 HOH 179 1279 13   HOH HOH A . 
M 3 HOH 180 1280 474  HOH HOH A . 
M 3 HOH 181 1281 606  HOH HOH A . 
M 3 HOH 182 1282 754  HOH HOH A . 
M 3 HOH 183 1283 10   HOH HOH A . 
M 3 HOH 184 1284 1124 HOH HOH A . 
M 3 HOH 185 1285 645  HOH HOH A . 
M 3 HOH 186 1286 55   HOH HOH A . 
M 3 HOH 187 1287 634  HOH HOH A . 
M 3 HOH 188 1288 831  HOH HOH A . 
M 3 HOH 189 1289 743  HOH HOH A . 
M 3 HOH 190 1290 633  HOH HOH A . 
M 3 HOH 191 1291 308  HOH HOH A . 
M 3 HOH 192 1292 804  HOH HOH A . 
M 3 HOH 193 1293 105  HOH HOH A . 
M 3 HOH 194 1294 701  HOH HOH A . 
M 3 HOH 195 1295 803  HOH HOH A . 
M 3 HOH 196 1296 1    HOH HOH A . 
M 3 HOH 197 1297 4    HOH HOH A . 
M 3 HOH 198 1298 58   HOH HOH A . 
M 3 HOH 199 1299 821  HOH HOH A . 
M 3 HOH 200 1300 426  HOH HOH A . 
M 3 HOH 201 1301 1013 HOH HOH A . 
M 3 HOH 202 1302 683  HOH HOH A . 
M 3 HOH 203 1303 5    HOH HOH A . 
M 3 HOH 204 1304 818  HOH HOH A . 
M 3 HOH 205 1305 669  HOH HOH A . 
M 3 HOH 206 1306 561  HOH HOH A . 
M 3 HOH 207 1307 61   HOH HOH A . 
M 3 HOH 208 1308 1022 HOH HOH A . 
M 3 HOH 209 1309 20   HOH HOH A . 
M 3 HOH 210 1310 671  HOH HOH A . 
N 3 HOH 1   1101 886  HOH HOH B . 
N 3 HOH 2   1102 480  HOH HOH B . 
N 3 HOH 3   1103 268  HOH HOH B . 
N 3 HOH 4   1104 36   HOH HOH B . 
N 3 HOH 5   1105 1027 HOH HOH B . 
N 3 HOH 6   1106 713  HOH HOH B . 
N 3 HOH 7   1107 520  HOH HOH B . 
N 3 HOH 8   1108 756  HOH HOH B . 
N 3 HOH 9   1109 866  HOH HOH B . 
N 3 HOH 10  1110 25   HOH HOH B . 
N 3 HOH 11  1111 82   HOH HOH B . 
N 3 HOH 12  1112 523  HOH HOH B . 
N 3 HOH 13  1113 1028 HOH HOH B . 
N 3 HOH 14  1114 451  HOH HOH B . 
N 3 HOH 15  1115 66   HOH HOH B . 
N 3 HOH 16  1116 861  HOH HOH B . 
N 3 HOH 17  1117 1115 HOH HOH B . 
N 3 HOH 18  1118 304  HOH HOH B . 
N 3 HOH 19  1119 165  HOH HOH B . 
N 3 HOH 20  1120 41   HOH HOH B . 
N 3 HOH 21  1121 317  HOH HOH B . 
N 3 HOH 22  1122 636  HOH HOH B . 
N 3 HOH 23  1123 276  HOH HOH B . 
N 3 HOH 24  1124 71   HOH HOH B . 
N 3 HOH 25  1125 266  HOH HOH B . 
N 3 HOH 26  1126 757  HOH HOH B . 
N 3 HOH 27  1127 733  HOH HOH B . 
N 3 HOH 28  1128 735  HOH HOH B . 
N 3 HOH 29  1129 648  HOH HOH B . 
N 3 HOH 30  1130 79   HOH HOH B . 
N 3 HOH 31  1131 262  HOH HOH B . 
N 3 HOH 32  1132 490  HOH HOH B . 
N 3 HOH 33  1133 676  HOH HOH B . 
N 3 HOH 34  1134 714  HOH HOH B . 
N 3 HOH 35  1135 321  HOH HOH B . 
N 3 HOH 36  1136 88   HOH HOH B . 
N 3 HOH 37  1137 175  HOH HOH B . 
N 3 HOH 38  1138 259  HOH HOH B . 
N 3 HOH 39  1139 87   HOH HOH B . 
N 3 HOH 40  1140 315  HOH HOH B . 
N 3 HOH 41  1141 494  HOH HOH B . 
N 3 HOH 42  1142 860  HOH HOH B . 
N 3 HOH 43  1143 693  HOH HOH B . 
N 3 HOH 44  1144 39   HOH HOH B . 
N 3 HOH 45  1145 412  HOH HOH B . 
N 3 HOH 46  1146 33   HOH HOH B . 
N 3 HOH 47  1147 473  HOH HOH B . 
N 3 HOH 48  1148 68   HOH HOH B . 
N 3 HOH 49  1149 316  HOH HOH B . 
N 3 HOH 50  1150 533  HOH HOH B . 
N 3 HOH 51  1151 858  HOH HOH B . 
N 3 HOH 52  1152 23   HOH HOH B . 
N 3 HOH 53  1153 80   HOH HOH B . 
N 3 HOH 54  1154 1039 HOH HOH B . 
N 3 HOH 55  1155 1132 HOH HOH B . 
N 3 HOH 56  1156 73   HOH HOH B . 
N 3 HOH 57  1157 81   HOH HOH B . 
N 3 HOH 58  1158 76   HOH HOH B . 
N 3 HOH 59  1159 34   HOH HOH B . 
N 3 HOH 60  1160 1106 HOH HOH B . 
N 3 HOH 61  1161 435  HOH HOH B . 
N 3 HOH 62  1162 739  HOH HOH B . 
N 3 HOH 63  1163 852  HOH HOH B . 
N 3 HOH 64  1164 531  HOH HOH B . 
N 3 HOH 65  1165 876  HOH HOH B . 
N 3 HOH 66  1166 442  HOH HOH B . 
N 3 HOH 67  1167 7    HOH HOH B . 
N 3 HOH 68  1168 667  HOH HOH B . 
N 3 HOH 69  1169 24   HOH HOH B . 
N 3 HOH 70  1170 460  HOH HOH B . 
N 3 HOH 71  1171 434  HOH HOH B . 
N 3 HOH 72  1172 1102 HOH HOH B . 
N 3 HOH 73  1173 857  HOH HOH B . 
N 3 HOH 74  1174 723  HOH HOH B . 
N 3 HOH 75  1175 173  HOH HOH B . 
N 3 HOH 76  1176 753  HOH HOH B . 
N 3 HOH 77  1177 1029 HOH HOH B . 
N 3 HOH 78  1178 496  HOH HOH B . 
N 3 HOH 79  1179 869  HOH HOH B . 
N 3 HOH 80  1180 752  HOH HOH B . 
N 3 HOH 81  1181 851  HOH HOH B . 
N 3 HOH 82  1182 801  HOH HOH B . 
N 3 HOH 83  1183 26   HOH HOH B . 
N 3 HOH 84  1184 67   HOH HOH B . 
N 3 HOH 85  1185 424  HOH HOH B . 
N 3 HOH 86  1186 438  HOH HOH B . 
N 3 HOH 87  1187 864  HOH HOH B . 
N 3 HOH 88  1188 879  HOH HOH B . 
N 3 HOH 89  1189 882  HOH HOH B . 
N 3 HOH 90  1190 738  HOH HOH B . 
N 3 HOH 91  1191 865  HOH HOH B . 
N 3 HOH 92  1192 28   HOH HOH B . 
N 3 HOH 93  1193 267  HOH HOH B . 
N 3 HOH 94  1194 525  HOH HOH B . 
N 3 HOH 95  1195 873  HOH HOH B . 
N 3 HOH 96  1196 38   HOH HOH B . 
N 3 HOH 97  1197 32   HOH HOH B . 
N 3 HOH 98  1198 178  HOH HOH B . 
N 3 HOH 99  1199 65   HOH HOH B . 
N 3 HOH 100 1200 555  HOH HOH B . 
N 3 HOH 101 1201 502  HOH HOH B . 
N 3 HOH 102 1202 887  HOH HOH B . 
N 3 HOH 103 1203 730  HOH HOH B . 
N 3 HOH 104 1204 35   HOH HOH B . 
N 3 HOH 105 1205 410  HOH HOH B . 
N 3 HOH 106 1206 31   HOH HOH B . 
N 3 HOH 107 1207 751  HOH HOH B . 
N 3 HOH 108 1208 85   HOH HOH B . 
N 3 HOH 109 1209 323  HOH HOH B . 
N 3 HOH 110 1210 859  HOH HOH B . 
N 3 HOH 111 1211 427  HOH HOH B . 
N 3 HOH 112 1212 487  HOH HOH B . 
N 3 HOH 113 1213 890  HOH HOH B . 
N 3 HOH 114 1214 872  HOH HOH B . 
N 3 HOH 115 1215 467  HOH HOH B . 
N 3 HOH 116 1216 661  HOH HOH B . 
N 3 HOH 117 1217 870  HOH HOH B . 
N 3 HOH 118 1218 482  HOH HOH B . 
N 3 HOH 119 1219 880  HOH HOH B . 
N 3 HOH 120 1220 814  HOH HOH B . 
N 3 HOH 121 1221 584  HOH HOH B . 
N 3 HOH 122 1222 179  HOH HOH B . 
N 3 HOH 123 1223 1118 HOH HOH B . 
N 3 HOH 124 1224 868  HOH HOH B . 
N 3 HOH 125 1225 319  HOH HOH B . 
N 3 HOH 126 1226 763  HOH HOH B . 
N 3 HOH 127 1227 1126 HOH HOH B . 
N 3 HOH 128 1228 863  HOH HOH B . 
N 3 HOH 129 1229 727  HOH HOH B . 
N 3 HOH 130 1230 867  HOH HOH B . 
N 3 HOH 131 1231 850  HOH HOH B . 
N 3 HOH 132 1232 662  HOH HOH B . 
N 3 HOH 133 1233 75   HOH HOH B . 
N 3 HOH 134 1234 884  HOH HOH B . 
N 3 HOH 135 1235 265  HOH HOH B . 
N 3 HOH 136 1236 891  HOH HOH B . 
N 3 HOH 137 1237 889  HOH HOH B . 
N 3 HOH 138 1238 407  HOH HOH B . 
N 3 HOH 139 1239 853  HOH HOH B . 
N 3 HOH 140 1240 78   HOH HOH B . 
N 3 HOH 141 1241 740  HOH HOH B . 
N 3 HOH 142 1242 862  HOH HOH B . 
N 3 HOH 143 1243 420  HOH HOH B . 
N 3 HOH 144 1244 854  HOH HOH B . 
N 3 HOH 145 1245 888  HOH HOH B . 
N 3 HOH 146 1246 416  HOH HOH B . 
N 3 HOH 147 1247 885  HOH HOH B . 
N 3 HOH 148 1248 176  HOH HOH B . 
N 3 HOH 149 1249 37   HOH HOH B . 
N 3 HOH 150 1250 11   HOH HOH B . 
N 3 HOH 151 1251 675  HOH HOH B . 
N 3 HOH 152 1252 874  HOH HOH B . 
N 3 HOH 153 1253 411  HOH HOH B . 
N 3 HOH 154 1254 177  HOH HOH B . 
N 3 HOH 155 1255 881  HOH HOH B . 
N 3 HOH 156 1256 579  HOH HOH B . 
N 3 HOH 157 1257 74   HOH HOH B . 
N 3 HOH 158 1258 239  HOH HOH B . 
N 3 HOH 159 1259 802  HOH HOH B . 
N 3 HOH 160 1260 30   HOH HOH B . 
N 3 HOH 161 1261 29   HOH HOH B . 
N 3 HOH 162 1262 646  HOH HOH B . 
N 3 HOH 163 1263 871  HOH HOH B . 
N 3 HOH 164 1264 878  HOH HOH B . 
N 3 HOH 165 1265 649  HOH HOH B . 
N 3 HOH 166 1266 647  HOH HOH B . 
N 3 HOH 167 1267 320  HOH HOH B . 
N 3 HOH 168 1268 263  HOH HOH B . 
N 3 HOH 169 1269 557  HOH HOH B . 
N 3 HOH 170 1270 429  HOH HOH B . 
N 3 HOH 171 1271 261  HOH HOH B . 
N 3 HOH 172 1272 734  HOH HOH B . 
N 3 HOH 173 1273 72   HOH HOH B . 
N 3 HOH 174 1274 1081 HOH HOH B . 
N 3 HOH 175 1275 472  HOH HOH B . 
N 3 HOH 176 1276 681  HOH HOH B . 
N 3 HOH 177 1277 689  HOH HOH B . 
N 3 HOH 178 1278 322  HOH HOH B . 
N 3 HOH 179 1279 69   HOH HOH B . 
N 3 HOH 180 1280 84   HOH HOH B . 
N 3 HOH 181 1281 678  HOH HOH B . 
N 3 HOH 182 1282 42   HOH HOH B . 
N 3 HOH 183 1283 174  HOH HOH B . 
N 3 HOH 184 1284 318  HOH HOH B . 
N 3 HOH 185 1285 481  HOH HOH B . 
N 3 HOH 186 1286 1030 HOH HOH B . 
N 3 HOH 187 1287 883  HOH HOH B . 
N 3 HOH 188 1288 1101 HOH HOH B . 
N 3 HOH 189 1289 725  HOH HOH B . 
N 3 HOH 190 1290 370  HOH HOH B . 
N 3 HOH 191 1291 258  HOH HOH B . 
N 3 HOH 192 1292 70   HOH HOH B . 
N 3 HOH 193 1293 583  HOH HOH B . 
N 3 HOH 194 1294 848  HOH HOH B . 
N 3 HOH 195 1295 260  HOH HOH B . 
O 3 HOH 1   1101 334  HOH HOH C . 
O 3 HOH 2   1102 923  HOH HOH C . 
O 3 HOH 3   1103 331  HOH HOH C . 
O 3 HOH 4   1104 89   HOH HOH C . 
O 3 HOH 5   1105 257  HOH HOH C . 
O 3 HOH 6   1106 1103 HOH HOH C . 
O 3 HOH 7   1107 92   HOH HOH C . 
O 3 HOH 8   1108 343  HOH HOH C . 
O 3 HOH 9   1109 245  HOH HOH C . 
O 3 HOH 10  1110 774  HOH HOH C . 
O 3 HOH 11  1111 1041 HOH HOH C . 
O 3 HOH 12  1112 673  HOH HOH C . 
O 3 HOH 13  1113 911  HOH HOH C . 
O 3 HOH 14  1114 188  HOH HOH C . 
O 3 HOH 15  1115 185  HOH HOH C . 
O 3 HOH 16  1116 109  HOH HOH C . 
O 3 HOH 17  1117 778  HOH HOH C . 
O 3 HOH 18  1118 233  HOH HOH C . 
O 3 HOH 19  1119 900  HOH HOH C . 
O 3 HOH 20  1120 1046 HOH HOH C . 
O 3 HOH 21  1121 897  HOH HOH C . 
O 3 HOH 22  1122 250  HOH HOH C . 
O 3 HOH 23  1123 895  HOH HOH C . 
O 3 HOH 24  1124 901  HOH HOH C . 
O 3 HOH 25  1125 915  HOH HOH C . 
O 3 HOH 26  1126 444  HOH HOH C . 
O 3 HOH 27  1127 246  HOH HOH C . 
O 3 HOH 28  1128 1076 HOH HOH C . 
O 3 HOH 29  1129 431  HOH HOH C . 
O 3 HOH 30  1130 532  HOH HOH C . 
O 3 HOH 31  1131 704  HOH HOH C . 
O 3 HOH 32  1132 1050 HOH HOH C . 
O 3 HOH 33  1133 228  HOH HOH C . 
O 3 HOH 34  1134 697  HOH HOH C . 
O 3 HOH 35  1135 330  HOH HOH C . 
O 3 HOH 36  1136 924  HOH HOH C . 
O 3 HOH 37  1137 243  HOH HOH C . 
O 3 HOH 38  1138 920  HOH HOH C . 
O 3 HOH 39  1139 352  HOH HOH C . 
O 3 HOH 40  1140 925  HOH HOH C . 
O 3 HOH 41  1141 351  HOH HOH C . 
O 3 HOH 42  1142 337  HOH HOH C . 
O 3 HOH 43  1143 552  HOH HOH C . 
O 3 HOH 44  1144 249  HOH HOH C . 
O 3 HOH 45  1145 189  HOH HOH C . 
O 3 HOH 46  1146 244  HOH HOH C . 
O 3 HOH 47  1147 255  HOH HOH C . 
O 3 HOH 48  1148 97   HOH HOH C . 
O 3 HOH 49  1149 326  HOH HOH C . 
O 3 HOH 50  1150 909  HOH HOH C . 
O 3 HOH 51  1151 912  HOH HOH C . 
O 3 HOH 52  1152 917  HOH HOH C . 
O 3 HOH 53  1153 12   HOH HOH C . 
O 3 HOH 54  1154 93   HOH HOH C . 
O 3 HOH 55  1155 254  HOH HOH C . 
O 3 HOH 56  1156 98   HOH HOH C . 
O 3 HOH 57  1157 44   HOH HOH C . 
O 3 HOH 58  1158 651  HOH HOH C . 
O 3 HOH 59  1159 182  HOH HOH C . 
O 3 HOH 60  1160 657  HOH HOH C . 
O 3 HOH 61  1161 90   HOH HOH C . 
O 3 HOH 62  1162 168  HOH HOH C . 
O 3 HOH 63  1163 432  HOH HOH C . 
O 3 HOH 64  1164 341  HOH HOH C . 
O 3 HOH 65  1165 750  HOH HOH C . 
O 3 HOH 66  1166 169  HOH HOH C . 
O 3 HOH 67  1167 339  HOH HOH C . 
O 3 HOH 68  1168 346  HOH HOH C . 
O 3 HOH 69  1169 896  HOH HOH C . 
O 3 HOH 70  1170 1104 HOH HOH C . 
O 3 HOH 71  1171 908  HOH HOH C . 
O 3 HOH 72  1172 922  HOH HOH C . 
O 3 HOH 73  1173 349  HOH HOH C . 
O 3 HOH 74  1174 698  HOH HOH C . 
O 3 HOH 75  1175 728  HOH HOH C . 
O 3 HOH 76  1176 574  HOH HOH C . 
O 3 HOH 77  1177 1031 HOH HOH C . 
O 3 HOH 78  1178 916  HOH HOH C . 
O 3 HOH 79  1179 1134 HOH HOH C . 
O 3 HOH 80  1180 102  HOH HOH C . 
O 3 HOH 81  1181 329  HOH HOH C . 
O 3 HOH 82  1182 902  HOH HOH C . 
O 3 HOH 83  1183 344  HOH HOH C . 
O 3 HOH 84  1184 511  HOH HOH C . 
O 3 HOH 85  1185 340  HOH HOH C . 
O 3 HOH 86  1186 477  HOH HOH C . 
O 3 HOH 87  1187 94   HOH HOH C . 
O 3 HOH 88  1188 478  HOH HOH C . 
O 3 HOH 89  1189 350  HOH HOH C . 
O 3 HOH 90  1190 653  HOH HOH C . 
O 3 HOH 91  1191 746  HOH HOH C . 
O 3 HOH 92  1192 99   HOH HOH C . 
O 3 HOH 93  1193 338  HOH HOH C . 
O 3 HOH 94  1194 652  HOH HOH C . 
O 3 HOH 95  1195 251  HOH HOH C . 
O 3 HOH 96  1196 253  HOH HOH C . 
O 3 HOH 97  1197 107  HOH HOH C . 
O 3 HOH 98  1198 769  HOH HOH C . 
O 3 HOH 99  1199 899  HOH HOH C . 
O 3 HOH 100 1200 497  HOH HOH C . 
O 3 HOH 101 1201 332  HOH HOH C . 
O 3 HOH 102 1202 134  HOH HOH C . 
O 3 HOH 103 1203 1077 HOH HOH C . 
O 3 HOH 104 1204 664  HOH HOH C . 
O 3 HOH 105 1205 898  HOH HOH C . 
O 3 HOH 106 1206 1135 HOH HOH C . 
O 3 HOH 107 1207 327  HOH HOH C . 
O 3 HOH 108 1208 921  HOH HOH C . 
O 3 HOH 109 1209 702  HOH HOH C . 
O 3 HOH 110 1210 699  HOH HOH C . 
O 3 HOH 111 1211 765  HOH HOH C . 
O 3 HOH 112 1212 95   HOH HOH C . 
O 3 HOH 113 1213 686  HOH HOH C . 
O 3 HOH 114 1214 913  HOH HOH C . 
O 3 HOH 115 1215 517  HOH HOH C . 
O 3 HOH 116 1216 328  HOH HOH C . 
O 3 HOH 117 1217 1043 HOH HOH C . 
O 3 HOH 118 1218 685  HOH HOH C . 
O 3 HOH 119 1219 1105 HOH HOH C . 
O 3 HOH 120 1220 782  HOH HOH C . 
O 3 HOH 121 1221 892  HOH HOH C . 
O 3 HOH 122 1222 721  HOH HOH C . 
O 3 HOH 123 1223 247  HOH HOH C . 
O 3 HOH 124 1224 905  HOH HOH C . 
O 3 HOH 125 1225 461  HOH HOH C . 
O 3 HOH 126 1226 462  HOH HOH C . 
O 3 HOH 127 1227 96   HOH HOH C . 
O 3 HOH 128 1228 493  HOH HOH C . 
O 3 HOH 129 1229 544  HOH HOH C . 
O 3 HOH 130 1230 747  HOH HOH C . 
O 3 HOH 131 1231 108  HOH HOH C . 
O 3 HOH 132 1232 788  HOH HOH C . 
O 3 HOH 133 1233 1079 HOH HOH C . 
O 3 HOH 134 1234 325  HOH HOH C . 
O 3 HOH 135 1235 894  HOH HOH C . 
O 3 HOH 136 1236 528  HOH HOH C . 
O 3 HOH 137 1237 453  HOH HOH C . 
O 3 HOH 138 1238 428  HOH HOH C . 
O 3 HOH 139 1239 104  HOH HOH C . 
O 3 HOH 140 1240 1032 HOH HOH C . 
O 3 HOH 141 1241 768  HOH HOH C . 
O 3 HOH 142 1242 342  HOH HOH C . 
O 3 HOH 143 1243 893  HOH HOH C . 
O 3 HOH 144 1244 650  HOH HOH C . 
O 3 HOH 145 1245 749  HOH HOH C . 
O 3 HOH 146 1246 907  HOH HOH C . 
O 3 HOH 147 1247 784  HOH HOH C . 
O 3 HOH 148 1248 324  HOH HOH C . 
O 3 HOH 149 1249 951  HOH HOH C . 
O 3 HOH 150 1250 1088 HOH HOH C . 
O 3 HOH 151 1251 690  HOH HOH C . 
O 3 HOH 152 1252 133  HOH HOH C . 
O 3 HOH 153 1253 914  HOH HOH C . 
O 3 HOH 154 1254 787  HOH HOH C . 
O 3 HOH 155 1255 903  HOH HOH C . 
O 3 HOH 156 1256 780  HOH HOH C . 
O 3 HOH 157 1257 241  HOH HOH C . 
O 3 HOH 158 1258 542  HOH HOH C . 
O 3 HOH 159 1259 184  HOH HOH C . 
O 3 HOH 160 1260 918  HOH HOH C . 
O 3 HOH 161 1261 556  HOH HOH C . 
O 3 HOH 162 1262 242  HOH HOH C . 
O 3 HOH 163 1263 1049 HOH HOH C . 
O 3 HOH 164 1264 22   HOH HOH C . 
O 3 HOH 165 1265 906  HOH HOH C . 
O 3 HOH 166 1266 333  HOH HOH C . 
O 3 HOH 167 1267 187  HOH HOH C . 
O 3 HOH 168 1268 43   HOH HOH C . 
O 3 HOH 169 1269 554  HOH HOH C . 
O 3 HOH 170 1270 91   HOH HOH C . 
O 3 HOH 171 1271 1025 HOH HOH C . 
O 3 HOH 172 1272 335  HOH HOH C . 
O 3 HOH 173 1273 475  HOH HOH C . 
O 3 HOH 174 1274 506  HOH HOH C . 
O 3 HOH 175 1275 183  HOH HOH C . 
O 3 HOH 176 1276 186  HOH HOH C . 
O 3 HOH 177 1277 904  HOH HOH C . 
O 3 HOH 178 1278 421  HOH HOH C . 
O 3 HOH 179 1279 703  HOH HOH C . 
O 3 HOH 180 1280 910  HOH HOH C . 
O 3 HOH 181 1281 418  HOH HOH C . 
O 3 HOH 182 1282 551  HOH HOH C . 
O 3 HOH 183 1283 248  HOH HOH C . 
O 3 HOH 184 1284 1044 HOH HOH C . 
O 3 HOH 185 1285 21   HOH HOH C . 
O 3 HOH 186 1286 1078 HOH HOH C . 
P 3 HOH 1   1101 654  HOH HOH D . 
P 3 HOH 2   1102 1045 HOH HOH D . 
P 3 HOH 3   1103 130  HOH HOH D . 
P 3 HOH 4   1104 569  HOH HOH D . 
P 3 HOH 5   1105 356  HOH HOH D . 
P 3 HOH 6   1106 943  HOH HOH D . 
P 3 HOH 7   1107 849  HOH HOH D . 
P 3 HOH 8   1108 785  HOH HOH D . 
P 3 HOH 9   1109 348  HOH HOH D . 
P 3 HOH 10  1110 64   HOH HOH D . 
P 3 HOH 11  1111 931  HOH HOH D . 
P 3 HOH 12  1112 643  HOH HOH D . 
P 3 HOH 13  1113 110  HOH HOH D . 
P 3 HOH 14  1114 731  HOH HOH D . 
P 3 HOH 15  1115 123  HOH HOH D . 
P 3 HOH 16  1116 930  HOH HOH D . 
P 3 HOH 17  1117 238  HOH HOH D . 
P 3 HOH 18  1118 953  HOH HOH D . 
P 3 HOH 19  1119 504  HOH HOH D . 
P 3 HOH 20  1120 125  HOH HOH D . 
P 3 HOH 21  1121 926  HOH HOH D . 
P 3 HOH 22  1122 572  HOH HOH D . 
P 3 HOH 23  1123 277  HOH HOH D . 
P 3 HOH 24  1124 448  HOH HOH D . 
P 3 HOH 25  1125 112  HOH HOH D . 
P 3 HOH 26  1126 565  HOH HOH D . 
P 3 HOH 27  1127 512  HOH HOH D . 
P 3 HOH 28  1128 124  HOH HOH D . 
P 3 HOH 29  1129 537  HOH HOH D . 
P 3 HOH 30  1130 136  HOH HOH D . 
P 3 HOH 31  1131 294  HOH HOH D . 
P 3 HOH 32  1132 121  HOH HOH D . 
P 3 HOH 33  1133 540  HOH HOH D . 
P 3 HOH 34  1134 417  HOH HOH D . 
P 3 HOH 35  1135 282  HOH HOH D . 
P 3 HOH 36  1136 1074 HOH HOH D . 
P 3 HOH 37  1137 371  HOH HOH D . 
P 3 HOH 38  1138 708  HOH HOH D . 
P 3 HOH 39  1139 729  HOH HOH D . 
P 3 HOH 40  1140 945  HOH HOH D . 
P 3 HOH 41  1141 558  HOH HOH D . 
P 3 HOH 42  1142 932  HOH HOH D . 
P 3 HOH 43  1143 280  HOH HOH D . 
P 3 HOH 44  1144 441  HOH HOH D . 
P 3 HOH 45  1145 799  HOH HOH D . 
P 3 HOH 46  1146 227  HOH HOH D . 
P 3 HOH 47  1147 944  HOH HOH D . 
P 3 HOH 48  1148 934  HOH HOH D . 
P 3 HOH 49  1149 936  HOH HOH D . 
P 3 HOH 50  1150 631  HOH HOH D . 
P 3 HOH 51  1151 530  HOH HOH D . 
P 3 HOH 52  1152 1107 HOH HOH D . 
P 3 HOH 53  1153 224  HOH HOH D . 
P 3 HOH 54  1154 724  HOH HOH D . 
P 3 HOH 55  1155 232  HOH HOH D . 
P 3 HOH 56  1156 560  HOH HOH D . 
P 3 HOH 57  1157 457  HOH HOH D . 
P 3 HOH 58  1158 111  HOH HOH D . 
P 3 HOH 59  1159 252  HOH HOH D . 
P 3 HOH 60  1160 536  HOH HOH D . 
P 3 HOH 61  1161 770  HOH HOH D . 
P 3 HOH 62  1162 285  HOH HOH D . 
P 3 HOH 63  1163 360  HOH HOH D . 
P 3 HOH 64  1164 797  HOH HOH D . 
P 3 HOH 65  1165 120  HOH HOH D . 
P 3 HOH 66  1166 877  HOH HOH D . 
P 3 HOH 67  1167 45   HOH HOH D . 
P 3 HOH 68  1168 443  HOH HOH D . 
P 3 HOH 69  1169 413  HOH HOH D . 
P 3 HOH 70  1170 658  HOH HOH D . 
P 3 HOH 71  1171 459  HOH HOH D . 
P 3 HOH 72  1172 941  HOH HOH D . 
P 3 HOH 73  1173 929  HOH HOH D . 
P 3 HOH 74  1174 281  HOH HOH D . 
P 3 HOH 75  1175 364  HOH HOH D . 
P 3 HOH 76  1176 129  HOH HOH D . 
P 3 HOH 77  1177 695  HOH HOH D . 
P 3 HOH 78  1178 938  HOH HOH D . 
P 3 HOH 79  1179 505  HOH HOH D . 
P 3 HOH 80  1180 655  HOH HOH D . 
P 3 HOH 81  1181 1114 HOH HOH D . 
P 3 HOH 82  1182 358  HOH HOH D . 
P 3 HOH 83  1183 118  HOH HOH D . 
P 3 HOH 84  1184 368  HOH HOH D . 
P 3 HOH 85  1185 927  HOH HOH D . 
P 3 HOH 86  1186 570  HOH HOH D . 
P 3 HOH 87  1187 632  HOH HOH D . 
P 3 HOH 88  1188 933  HOH HOH D . 
P 3 HOH 89  1189 470  HOH HOH D . 
P 3 HOH 90  1190 766  HOH HOH D . 
P 3 HOH 91  1191 113  HOH HOH D . 
P 3 HOH 92  1192 562  HOH HOH D . 
P 3 HOH 93  1193 952  HOH HOH D . 
P 3 HOH 94  1194 353  HOH HOH D . 
P 3 HOH 95  1195 115  HOH HOH D . 
P 3 HOH 96  1196 128  HOH HOH D . 
P 3 HOH 97  1197 660  HOH HOH D . 
P 3 HOH 98  1198 114  HOH HOH D . 
P 3 HOH 99  1199 1052 HOH HOH D . 
P 3 HOH 100 1200 736  HOH HOH D . 
P 3 HOH 101 1201 642  HOH HOH D . 
P 3 HOH 102 1202 235  HOH HOH D . 
P 3 HOH 103 1203 223  HOH HOH D . 
P 3 HOH 104 1204 1127 HOH HOH D . 
P 3 HOH 105 1205 777  HOH HOH D . 
P 3 HOH 106 1206 638  HOH HOH D . 
P 3 HOH 107 1207 1034 HOH HOH D . 
P 3 HOH 108 1208 240  HOH HOH D . 
P 3 HOH 109 1209 488  HOH HOH D . 
P 3 HOH 110 1210 492  HOH HOH D . 
P 3 HOH 111 1211 119  HOH HOH D . 
P 3 HOH 112 1212 463  HOH HOH D . 
P 3 HOH 113 1213 510  HOH HOH D . 
P 3 HOH 114 1214 126  HOH HOH D . 
P 3 HOH 115 1215 405  HOH HOH D . 
P 3 HOH 116 1216 942  HOH HOH D . 
P 3 HOH 117 1217 715  HOH HOH D . 
P 3 HOH 118 1218 1035 HOH HOH D . 
P 3 HOH 119 1219 545  HOH HOH D . 
P 3 HOH 120 1220 284  HOH HOH D . 
P 3 HOH 121 1221 452  HOH HOH D . 
P 3 HOH 122 1222 131  HOH HOH D . 
P 3 HOH 123 1223 663  HOH HOH D . 
P 3 HOH 124 1224 180  HOH HOH D . 
P 3 HOH 125 1225 498  HOH HOH D . 
P 3 HOH 126 1226 1125 HOH HOH D . 
P 3 HOH 127 1227 464  HOH HOH D . 
P 3 HOH 128 1228 230  HOH HOH D . 
P 3 HOH 129 1229 948  HOH HOH D . 
P 3 HOH 130 1230 1123 HOH HOH D . 
P 3 HOH 131 1231 100  HOH HOH D . 
P 3 HOH 132 1232 225  HOH HOH D . 
P 3 HOH 133 1233 694  HOH HOH D . 
P 3 HOH 134 1234 798  HOH HOH D . 
P 3 HOH 135 1235 950  HOH HOH D . 
P 3 HOH 136 1236 576  HOH HOH D . 
P 3 HOH 137 1237 939  HOH HOH D . 
P 3 HOH 138 1238 234  HOH HOH D . 
P 3 HOH 139 1239 1131 HOH HOH D . 
P 3 HOH 140 1240 127  HOH HOH D . 
P 3 HOH 141 1241 792  HOH HOH D . 
P 3 HOH 142 1242 485  HOH HOH D . 
P 3 HOH 143 1243 256  HOH HOH D . 
P 3 HOH 144 1244 414  HOH HOH D . 
P 3 HOH 145 1245 566  HOH HOH D . 
P 3 HOH 146 1246 1130 HOH HOH D . 
P 3 HOH 147 1247 116  HOH HOH D . 
P 3 HOH 148 1248 363  HOH HOH D . 
P 3 HOH 149 1249 524  HOH HOH D . 
P 3 HOH 150 1250 761  HOH HOH D . 
P 3 HOH 151 1251 501  HOH HOH D . 
P 3 HOH 152 1252 1042 HOH HOH D . 
P 3 HOH 153 1253 946  HOH HOH D . 
P 3 HOH 154 1254 357  HOH HOH D . 
P 3 HOH 155 1255 509  HOH HOH D . 
P 3 HOH 156 1256 534  HOH HOH D . 
P 3 HOH 157 1257 1051 HOH HOH D . 
P 3 HOH 158 1258 762  HOH HOH D . 
P 3 HOH 159 1259 483  HOH HOH D . 
P 3 HOH 160 1260 361  HOH HOH D . 
P 3 HOH 161 1261 644  HOH HOH D . 
P 3 HOH 162 1262 659  HOH HOH D . 
P 3 HOH 163 1263 365  HOH HOH D . 
P 3 HOH 164 1264 716  HOH HOH D . 
P 3 HOH 165 1265 367  HOH HOH D . 
P 3 HOH 166 1266 40   HOH HOH D . 
P 3 HOH 167 1267 1089 HOH HOH D . 
P 3 HOH 168 1268 639  HOH HOH D . 
P 3 HOH 169 1269 790  HOH HOH D . 
P 3 HOH 170 1270 919  HOH HOH D . 
P 3 HOH 171 1271 755  HOH HOH D . 
P 3 HOH 172 1272 231  HOH HOH D . 
P 3 HOH 173 1273 86   HOH HOH D . 
P 3 HOH 174 1274 46   HOH HOH D . 
P 3 HOH 175 1275 419  HOH HOH D . 
P 3 HOH 176 1276 947  HOH HOH D . 
P 3 HOH 177 1277 77   HOH HOH D . 
P 3 HOH 178 1278 764  HOH HOH D . 
P 3 HOH 179 1279 354  HOH HOH D . 
P 3 HOH 180 1280 359  HOH HOH D . 
P 3 HOH 181 1281 345  HOH HOH D . 
P 3 HOH 182 1282 585  HOH HOH D . 
P 3 HOH 183 1283 641  HOH HOH D . 
P 3 HOH 184 1284 575  HOH HOH D . 
P 3 HOH 185 1285 717  HOH HOH D . 
P 3 HOH 186 1286 132  HOH HOH D . 
P 3 HOH 187 1287 935  HOH HOH D . 
P 3 HOH 188 1288 226  HOH HOH D . 
P 3 HOH 189 1289 1040 HOH HOH D . 
P 3 HOH 190 1290 1122 HOH HOH D . 
P 3 HOH 191 1291 229  HOH HOH D . 
P 3 HOH 192 1292 800  HOH HOH D . 
P 3 HOH 193 1293 135  HOH HOH D . 
P 3 HOH 194 1294 122  HOH HOH D . 
P 3 HOH 195 1295 696  HOH HOH D . 
P 3 HOH 196 1296 767  HOH HOH D . 
P 3 HOH 197 1297 192  HOH HOH D . 
P 3 HOH 198 1298 362  HOH HOH D . 
P 3 HOH 199 1299 279  HOH HOH D . 
P 3 HOH 200 1300 369  HOH HOH D . 
P 3 HOH 201 1301 117  HOH HOH D . 
P 3 HOH 202 1302 347  HOH HOH D . 
P 3 HOH 203 1303 101  HOH HOH D . 
P 3 HOH 204 1304 949  HOH HOH D . 
P 3 HOH 205 1305 513  HOH HOH D . 
P 3 HOH 206 1306 278  HOH HOH D . 
P 3 HOH 207 1307 937  HOH HOH D . 
P 3 HOH 208 1308 1073 HOH HOH D . 
P 3 HOH 209 1309 283  HOH HOH D . 
P 3 HOH 210 1310 795  HOH HOH D . 
P 3 HOH 211 1311 640  HOH HOH D . 
P 3 HOH 212 1312 990  HOH HOH D . 
P 3 HOH 213 1313 1075 HOH HOH D . 
P 3 HOH 214 1314 796  HOH HOH D . 
P 3 HOH 215 1315 732  HOH HOH D . 
P 3 HOH 216 1316 237  HOH HOH D . 
P 3 HOH 217 1317 875  HOH HOH D . 
P 3 HOH 218 1318 1033 HOH HOH D . 
P 3 HOH 219 1319 489  HOH HOH D . 
P 3 HOH 220 1320 737  HOH HOH D . 
P 3 HOH 221 1321 170  HOH HOH D . 
P 3 HOH 222 1322 355  HOH HOH D . 
P 3 HOH 223 1323 656  HOH HOH D . 
P 3 HOH 224 1324 236  HOH HOH D . 
P 3 HOH 225 1325 366  HOH HOH D . 
P 3 HOH 226 1326 181  HOH HOH D . 
P 3 HOH 227 1327 83   HOH HOH D . 
P 3 HOH 228 1328 928  HOH HOH D . 
Q 3 HOH 1   1101 378  HOH HOH E . 
Q 3 HOH 2   1102 375  HOH HOH E . 
Q 3 HOH 3   1103 388  HOH HOH E . 
Q 3 HOH 4   1104 205  HOH HOH E . 
Q 3 HOH 5   1105 508  HOH HOH E . 
Q 3 HOH 6   1106 609  HOH HOH E . 
Q 3 HOH 7   1107 541  HOH HOH E . 
Q 3 HOH 8   1108 373  HOH HOH E . 
Q 3 HOH 9   1109 981  HOH HOH E . 
Q 3 HOH 10  1110 495  HOH HOH E . 
Q 3 HOH 11  1111 978  HOH HOH E . 
Q 3 HOH 12  1112 1067 HOH HOH E . 
Q 3 HOH 13  1113 518  HOH HOH E . 
Q 3 HOH 14  1114 1012 HOH HOH E . 
Q 3 HOH 15  1115 591  HOH HOH E . 
Q 3 HOH 16  1116 573  HOH HOH E . 
Q 3 HOH 17  1117 1094 HOH HOH E . 
Q 3 HOH 18  1118 208  HOH HOH E . 
Q 3 HOH 19  1119 598  HOH HOH E . 
Q 3 HOH 20  1120 977  HOH HOH E . 
Q 3 HOH 21  1121 1133 HOH HOH E . 
Q 3 HOH 22  1122 386  HOH HOH E . 
Q 3 HOH 23  1123 961  HOH HOH E . 
Q 3 HOH 24  1124 289  HOH HOH E . 
Q 3 HOH 25  1125 138  HOH HOH E . 
Q 3 HOH 26  1126 980  HOH HOH E . 
Q 3 HOH 27  1127 527  HOH HOH E . 
Q 3 HOH 28  1128 596  HOH HOH E . 
Q 3 HOH 29  1129 212  HOH HOH E . 
Q 3 HOH 30  1130 963  HOH HOH E . 
Q 3 HOH 31  1131 1053 HOH HOH E . 
Q 3 HOH 32  1132 559  HOH HOH E . 
Q 3 HOH 33  1133 1113 HOH HOH E . 
Q 3 HOH 34  1134 382  HOH HOH E . 
Q 3 HOH 35  1135 380  HOH HOH E . 
Q 3 HOH 36  1136 507  HOH HOH E . 
Q 3 HOH 37  1137 1121 HOH HOH E . 
Q 3 HOH 38  1138 626  HOH HOH E . 
Q 3 HOH 39  1139 290  HOH HOH E . 
Q 3 HOH 40  1140 595  HOH HOH E . 
Q 3 HOH 41  1141 204  HOH HOH E . 
Q 3 HOH 42  1142 154  HOH HOH E . 
Q 3 HOH 43  1143 973  HOH HOH E . 
Q 3 HOH 44  1144 217  HOH HOH E . 
Q 3 HOH 45  1145 476  HOH HOH E . 
Q 3 HOH 46  1146 377  HOH HOH E . 
Q 3 HOH 47  1147 758  HOH HOH E . 
Q 3 HOH 48  1148 603  HOH HOH E . 
Q 3 HOH 49  1149 665  HOH HOH E . 
Q 3 HOH 50  1150 287  HOH HOH E . 
Q 3 HOH 51  1151 666  HOH HOH E . 
Q 3 HOH 52  1152 372  HOH HOH E . 
Q 3 HOH 53  1153 503  HOH HOH E . 
Q 3 HOH 54  1154 300  HOH HOH E . 
Q 3 HOH 55  1155 447  HOH HOH E . 
Q 3 HOH 56  1156 976  HOH HOH E . 
Q 3 HOH 57  1157 1054 HOH HOH E . 
Q 3 HOH 58  1158 957  HOH HOH E . 
Q 3 HOH 59  1159 972  HOH HOH E . 
Q 3 HOH 60  1160 379  HOH HOH E . 
Q 3 HOH 61  1161 376  HOH HOH E . 
Q 3 HOH 62  1162 959  HOH HOH E . 
Q 3 HOH 63  1163 302  HOH HOH E . 
Q 3 HOH 64  1164 546  HOH HOH E . 
Q 3 HOH 65  1165 301  HOH HOH E . 
Q 3 HOH 66  1166 1072 HOH HOH E . 
Q 3 HOH 67  1167 599  HOH HOH E . 
Q 3 HOH 68  1168 384  HOH HOH E . 
Q 3 HOH 69  1169 1069 HOH HOH E . 
Q 3 HOH 70  1170 964  HOH HOH E . 
Q 3 HOH 71  1171 604  HOH HOH E . 
Q 3 HOH 72  1172 374  HOH HOH E . 
Q 3 HOH 73  1173 960  HOH HOH E . 
Q 3 HOH 74  1174 962  HOH HOH E . 
Q 3 HOH 75  1175 592  HOH HOH E . 
Q 3 HOH 76  1176 1090 HOH HOH E . 
Q 3 HOH 77  1177 387  HOH HOH E . 
Q 3 HOH 78  1178 458  HOH HOH E . 
Q 3 HOH 79  1179 203  HOH HOH E . 
Q 3 HOH 80  1180 221  HOH HOH E . 
Q 3 HOH 81  1181 141  HOH HOH E . 
Q 3 HOH 82  1182 215  HOH HOH E . 
Q 3 HOH 83  1183 1093 HOH HOH E . 
Q 3 HOH 84  1184 965  HOH HOH E . 
Q 3 HOH 85  1185 137  HOH HOH E . 
Q 3 HOH 86  1186 975  HOH HOH E . 
Q 3 HOH 87  1187 597  HOH HOH E . 
Q 3 HOH 88  1188 139  HOH HOH E . 
Q 3 HOH 89  1189 385  HOH HOH E . 
Q 3 HOH 90  1190 707  HOH HOH E . 
Q 3 HOH 91  1191 207  HOH HOH E . 
Q 3 HOH 92  1192 521  HOH HOH E . 
Q 3 HOH 93  1193 214  HOH HOH E . 
Q 3 HOH 94  1194 588  HOH HOH E . 
Q 3 HOH 95  1195 616  HOH HOH E . 
Q 3 HOH 96  1196 625  HOH HOH E . 
Q 3 HOH 97  1197 954  HOH HOH E . 
Q 3 HOH 98  1198 593  HOH HOH E . 
Q 3 HOH 99  1199 819  HOH HOH E . 
Q 3 HOH 100 1200 1112 HOH HOH E . 
Q 3 HOH 101 1201 605  HOH HOH E . 
Q 3 HOH 102 1202 955  HOH HOH E . 
Q 3 HOH 103 1203 590  HOH HOH E . 
Q 3 HOH 104 1204 600  HOH HOH E . 
Q 3 HOH 105 1205 209  HOH HOH E . 
Q 3 HOH 106 1206 968  HOH HOH E . 
Q 3 HOH 107 1207 218  HOH HOH E . 
Q 3 HOH 108 1208 956  HOH HOH E . 
Q 3 HOH 109 1209 958  HOH HOH E . 
Q 3 HOH 110 1210 202  HOH HOH E . 
Q 3 HOH 111 1211 589  HOH HOH E . 
Q 3 HOH 112 1212 550  HOH HOH E . 
Q 3 HOH 113 1213 771  HOH HOH E . 
Q 3 HOH 114 1214 568  HOH HOH E . 
Q 3 HOH 115 1215 454  HOH HOH E . 
Q 3 HOH 116 1216 213  HOH HOH E . 
Q 3 HOH 117 1217 286  HOH HOH E . 
Q 3 HOH 118 1218 383  HOH HOH E . 
Q 3 HOH 119 1219 1055 HOH HOH E . 
Q 3 HOH 120 1220 210  HOH HOH E . 
Q 3 HOH 121 1221 571  HOH HOH E . 
Q 3 HOH 122 1222 206  HOH HOH E . 
Q 3 HOH 123 1223 145  HOH HOH E . 
Q 3 HOH 124 1224 966  HOH HOH E . 
Q 3 HOH 125 1225 423  HOH HOH E . 
Q 3 HOH 126 1226 486  HOH HOH E . 
Q 3 HOH 127 1227 422  HOH HOH E . 
Q 3 HOH 128 1228 162  HOH HOH E . 
Q 3 HOH 129 1229 140  HOH HOH E . 
Q 3 HOH 130 1230 1092 HOH HOH E . 
Q 3 HOH 131 1231 718  HOH HOH E . 
Q 3 HOH 132 1232 381  HOH HOH E . 
Q 3 HOH 133 1233 705  HOH HOH E . 
Q 3 HOH 134 1234 967  HOH HOH E . 
Q 3 HOH 135 1235 535  HOH HOH E . 
Q 3 HOH 136 1236 216  HOH HOH E . 
Q 3 HOH 137 1237 1016 HOH HOH E . 
Q 3 HOH 138 1238 706  HOH HOH E . 
Q 3 HOH 139 1239 974  HOH HOH E . 
Q 3 HOH 140 1240 1091 HOH HOH E . 
Q 3 HOH 141 1241 142  HOH HOH E . 
Q 3 HOH 142 1242 222  HOH HOH E . 
Q 3 HOH 143 1243 1071 HOH HOH E . 
Q 3 HOH 144 1244 1065 HOH HOH E . 
Q 3 HOH 145 1245 1068 HOH HOH E . 
Q 3 HOH 146 1246 602  HOH HOH E . 
Q 3 HOH 147 1247 288  HOH HOH E . 
Q 3 HOH 148 1248 601  HOH HOH E . 
Q 3 HOH 149 1249 1057 HOH HOH E . 
R 3 HOH 1   1101 296  HOH HOH F . 
R 3 HOH 2   1102 629  HOH HOH F . 
R 3 HOH 3   1103 1120 HOH HOH F . 
R 3 HOH 4   1104 439  HOH HOH F . 
R 3 HOH 5   1105 1011 HOH HOH F . 
R 3 HOH 6   1106 514  HOH HOH F . 
R 3 HOH 7   1107 1003 HOH HOH F . 
R 3 HOH 8   1108 402  HOH HOH F . 
R 3 HOH 9   1109 1058 HOH HOH F . 
R 3 HOH 10  1110 1062 HOH HOH F . 
R 3 HOH 11  1111 394  HOH HOH F . 
R 3 HOH 12  1112 158  HOH HOH F . 
R 3 HOH 13  1113 775  HOH HOH F . 
R 3 HOH 14  1114 1066 HOH HOH F . 
R 3 HOH 15  1115 1000 HOH HOH F . 
R 3 HOH 16  1116 759  HOH HOH F . 
R 3 HOH 17  1117 969  HOH HOH F . 
R 3 HOH 18  1118 1018 HOH HOH F . 
R 3 HOH 19  1119 479  HOH HOH F . 
R 3 HOH 20  1120 395  HOH HOH F . 
R 3 HOH 21  1121 607  HOH HOH F . 
R 3 HOH 22  1122 710  HOH HOH F . 
R 3 HOH 23  1123 989  HOH HOH F . 
R 3 HOH 24  1124 149  HOH HOH F . 
R 3 HOH 25  1125 150  HOH HOH F . 
R 3 HOH 26  1126 1111 HOH HOH F . 
R 3 HOH 27  1127 1128 HOH HOH F . 
R 3 HOH 28  1128 392  HOH HOH F . 
R 3 HOH 29  1129 295  HOH HOH F . 
R 3 HOH 30  1130 709  HOH HOH F . 
R 3 HOH 31  1131 491  HOH HOH F . 
R 3 HOH 32  1132 1095 HOH HOH F . 
R 3 HOH 33  1133 313  HOH HOH F . 
R 3 HOH 34  1134 748  HOH HOH F . 
R 3 HOH 35  1135 293  HOH HOH F . 
R 3 HOH 36  1136 1005 HOH HOH F . 
R 3 HOH 37  1137 433  HOH HOH F . 
R 3 HOH 38  1138 147  HOH HOH F . 
R 3 HOH 39  1139 195  HOH HOH F . 
R 3 HOH 40  1140 291  HOH HOH F . 
R 3 HOH 41  1141 630  HOH HOH F . 
R 3 HOH 42  1142 161  HOH HOH F . 
R 3 HOH 43  1143 408  HOH HOH F . 
R 3 HOH 44  1144 220  HOH HOH F . 
R 3 HOH 45  1145 547  HOH HOH F . 
R 3 HOH 46  1146 1084 HOH HOH F . 
R 3 HOH 47  1147 628  HOH HOH F . 
R 3 HOH 48  1148 1010 HOH HOH F . 
R 3 HOH 49  1149 622  HOH HOH F . 
R 3 HOH 50  1150 1015 HOH HOH F . 
R 3 HOH 51  1151 144  HOH HOH F . 
R 3 HOH 52  1152 987  HOH HOH F . 
R 3 HOH 53  1153 988  HOH HOH F . 
R 3 HOH 54  1154 298  HOH HOH F . 
R 3 HOH 55  1155 995  HOH HOH F . 
R 3 HOH 56  1156 1129 HOH HOH F . 
R 3 HOH 57  1157 791  HOH HOH F . 
R 3 HOH 58  1158 1007 HOH HOH F . 
R 3 HOH 59  1159 996  HOH HOH F . 
R 3 HOH 60  1160 159  HOH HOH F . 
R 3 HOH 61  1161 1008 HOH HOH F . 
R 3 HOH 62  1162 415  HOH HOH F . 
R 3 HOH 63  1163 1001 HOH HOH F . 
R 3 HOH 64  1164 391  HOH HOH F . 
R 3 HOH 65  1165 1110 HOH HOH F . 
R 3 HOH 66  1166 999  HOH HOH F . 
R 3 HOH 67  1167 553  HOH HOH F . 
R 3 HOH 68  1168 404  HOH HOH F . 
R 3 HOH 69  1169 1109 HOH HOH F . 
R 3 HOH 70  1170 449  HOH HOH F . 
R 3 HOH 71  1171 155  HOH HOH F . 
R 3 HOH 72  1172 1002 HOH HOH F . 
R 3 HOH 73  1173 292  HOH HOH F . 
R 3 HOH 74  1174 399  HOH HOH F . 
R 3 HOH 75  1175 466  HOH HOH F . 
R 3 HOH 76  1176 994  HOH HOH F . 
R 3 HOH 77  1177 997  HOH HOH F . 
R 3 HOH 78  1178 522  HOH HOH F . 
R 3 HOH 79  1179 400  HOH HOH F . 
R 3 HOH 80  1180 624  HOH HOH F . 
R 3 HOH 81  1181 971  HOH HOH F . 
R 3 HOH 82  1182 157  HOH HOH F . 
R 3 HOH 83  1183 499  HOH HOH F . 
R 3 HOH 84  1184 623  HOH HOH F . 
R 3 HOH 85  1185 199  HOH HOH F . 
R 3 HOH 86  1186 471  HOH HOH F . 
R 3 HOH 87  1187 146  HOH HOH F . 
R 3 HOH 88  1188 201  HOH HOH F . 
R 3 HOH 89  1189 143  HOH HOH F . 
R 3 HOH 90  1190 984  HOH HOH F . 
R 3 HOH 91  1191 1017 HOH HOH F . 
R 3 HOH 92  1192 519  HOH HOH F . 
R 3 HOH 93  1193 156  HOH HOH F . 
R 3 HOH 94  1194 148  HOH HOH F . 
R 3 HOH 95  1195 1061 HOH HOH F . 
R 3 HOH 96  1196 160  HOH HOH F . 
R 3 HOH 97  1197 1064 HOH HOH F . 
R 3 HOH 98  1198 1108 HOH HOH F . 
R 3 HOH 99  1199 985  HOH HOH F . 
R 3 HOH 100 1200 299  HOH HOH F . 
R 3 HOH 101 1201 1059 HOH HOH F . 
R 3 HOH 102 1202 401  HOH HOH F . 
R 3 HOH 103 1203 396  HOH HOH F . 
R 3 HOH 104 1204 468  HOH HOH F . 
R 3 HOH 105 1205 993  HOH HOH F . 
R 3 HOH 106 1206 711  HOH HOH F . 
R 3 HOH 107 1207 198  HOH HOH F . 
R 3 HOH 108 1208 611  HOH HOH F . 
R 3 HOH 109 1209 538  HOH HOH F . 
R 3 HOH 110 1210 986  HOH HOH F . 
R 3 HOH 111 1211 610  HOH HOH F . 
R 3 HOH 112 1212 151  HOH HOH F . 
R 3 HOH 113 1213 614  HOH HOH F . 
R 3 HOH 114 1214 744  HOH HOH F . 
R 3 HOH 115 1215 450  HOH HOH F . 
R 3 HOH 116 1216 982  HOH HOH F . 
R 3 HOH 117 1217 618  HOH HOH F . 
R 3 HOH 118 1218 1098 HOH HOH F . 
R 3 HOH 119 1219 776  HOH HOH F . 
R 3 HOH 120 1220 627  HOH HOH F . 
R 3 HOH 121 1221 1097 HOH HOH F . 
R 3 HOH 122 1222 594  HOH HOH F . 
R 3 HOH 123 1223 1006 HOH HOH F . 
R 3 HOH 124 1224 979  HOH HOH F . 
R 3 HOH 125 1225 615  HOH HOH F . 
R 3 HOH 126 1226 397  HOH HOH F . 
R 3 HOH 127 1227 581  HOH HOH F . 
R 3 HOH 128 1228 152  HOH HOH F . 
R 3 HOH 129 1229 998  HOH HOH F . 
R 3 HOH 130 1230 193  HOH HOH F . 
R 3 HOH 131 1231 564  HOH HOH F . 
R 3 HOH 132 1232 613  HOH HOH F . 
R 3 HOH 133 1233 196  HOH HOH F . 
R 3 HOH 134 1234 153  HOH HOH F . 
R 3 HOH 135 1235 577  HOH HOH F . 
R 3 HOH 136 1236 608  HOH HOH F . 
R 3 HOH 137 1237 970  HOH HOH F . 
R 3 HOH 138 1238 621  HOH HOH F . 
R 3 HOH 139 1239 403  HOH HOH F . 
R 3 HOH 140 1240 1100 HOH HOH F . 
R 3 HOH 141 1241 1004 HOH HOH F . 
R 3 HOH 142 1242 1096 HOH HOH F . 
R 3 HOH 143 1243 200  HOH HOH F . 
R 3 HOH 144 1244 991  HOH HOH F . 
R 3 HOH 145 1245 1070 HOH HOH F . 
R 3 HOH 146 1246 197  HOH HOH F . 
R 3 HOH 147 1247 580  HOH HOH F . 
R 3 HOH 148 1248 1056 HOH HOH F . 
R 3 HOH 149 1249 781  HOH HOH F . 
R 3 HOH 150 1250 612  HOH HOH F . 
R 3 HOH 151 1251 992  HOH HOH F . 
R 3 HOH 152 1252 712  HOH HOH F . 
R 3 HOH 153 1253 389  HOH HOH F . 
R 3 HOH 154 1254 211  HOH HOH F . 
R 3 HOH 155 1255 940  HOH HOH F . 
R 3 HOH 156 1256 983  HOH HOH F . 
R 3 HOH 157 1257 539  HOH HOH F . 
R 3 HOH 158 1258 617  HOH HOH F . 
R 3 HOH 159 1259 194  HOH HOH F . 
R 3 HOH 160 1260 1060 HOH HOH F . 
R 3 HOH 161 1261 219  HOH HOH F . 
R 3 HOH 162 1262 297  HOH HOH F . 
R 3 HOH 163 1263 393  HOH HOH F . 
R 3 HOH 164 1264 1009 HOH HOH F . 
R 3 HOH 165 1265 587  HOH HOH F . 
R 3 HOH 166 1266 1099 HOH HOH F . 
R 3 HOH 167 1267 1119 HOH HOH F . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0430 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP  ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9HZ1 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     167.832 
_cell.length_a_esd                 ? 
_cell.length_b                     309.991 
_cell.length_b_esd                 ? 
_cell.length_c                     175.268 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        48 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9HZ1 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9HZ1 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             4.05 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          69.64 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '3% PEG 8000, 25% MPD, 7% Taximate pH 5' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            294 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2014-05-08 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97924 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ALBA BEAMLINE XALOC' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97924 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   XALOC 
_diffrn_source.pdbx_synchrotron_site       ALBA 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9HZ1 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.4 
_reflns.d_resolution_low                               49.2 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     177281 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                7.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          11.0 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.0062 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.4 
_reflns_shell.d_res_low                                     2.44 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.3 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             8725 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               6.5 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.377 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -1.20 
_refine.aniso_B[1][2]                            -0.00 
_refine.aniso_B[1][3]                            0.00 
_refine.aniso_B[2][2]                            0.90 
_refine.aniso_B[2][3]                            -0.00 
_refine.aniso_B[3][3]                            0.30 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               33.514 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.957 
_refine.correlation_coeff_Fo_to_Fc_free          0.947 
_refine.details                                  'HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9HZ1 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.40 
_refine.ls_d_res_low                             48.67 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     168584 
_refine.ls_number_reflns_R_free                  8663 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.96 
_refine.ls_percent_reflns_R_free                 4.9 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.16549 
_refine.ls_R_factor_R_free                       0.18953 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.16426 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.199 
_refine.pdbx_overall_ESU_R_Free                  0.163 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             5.043 
_refine.overall_SU_ML                            0.112 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.40 
_refine_hist.d_res_low                        48.67 
_refine_hist.number_atoms_solvent             1135 
_refine_hist.number_atoms_total               20877 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        19622 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         120 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.009  0.012  20333 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 1.816  1.801  27746 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.378  5.000  2439  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 10.323 5.000  132   ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 13.516 10.000 3102  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.133  0.200  2995  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.008  0.020  16096 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 3.627  3.117  9786  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 5.345  5.574  12212 ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 5.650  3.503  10547 ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 9.434  31.23  30156 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.400 
_refine_ls_shell.d_res_low                        2.462 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             696 
_refine_ls_shell.number_reflns_R_work             12291 
_refine_ls_shell.percent_reflns_obs               99.99 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.272 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.271 
# 
_struct.entry_id                     9HZ1 
_struct.title                        'Crystal structure of AlfB' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9HZ1 
_struct_keywords.text            'Fucosidase, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 1 ? 
F N N 1 ? 
G N N 2 ? 
H N N 2 ? 
I N N 2 ? 
J N N 2 ? 
K N N 2 ? 
L N N 2 ? 
M N N 3 ? 
N N N 3 ? 
O N N 3 ? 
P N N 3 ? 
Q N N 3 ? 
R N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A806EKD1_LACCD 
_struct_ref.pdbx_db_accession          A0A806EKD1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MTEPLPRIQHYEDLGLGLFIHWGLYSQMAVGEWTELIHHRNQHDYEQLIKTFTAAQFDAKKIAHAAKAVGAKYIVLTTKH
HEGFFLYDTKGLSDFDVMHAPARRDLIAEFVAACREEDLLPFFYMATYDWHTPLYDDDFPAYLTYLQKSVEVLCRNYGPV
GGFWFDGNWNKKDADWHLPELYGMIRHYQPNAIIVNNTGLKNRGQVSDPEIDVVTYERRTPDEIYHGAPNEKYVAGEISI
TLNQHWGIAANDLNYKSPAEVIETVAHARHIGANILVNIGLTGTGAIPAAAQTYMHLLGRWTAMAAPVLYKGRPVPVTSA
HGTRDFVLHTSKHDFLCILDLQVVGNDNVVLGGEGVNPRSFVGIGQPIQRIHWLDNDEVLSFTQDLDKKVLTVDATGYPY
GSDWVVRIAQIDYE
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9HZ1 A 1 ? 414 ? A0A806EKD1 1 ? 414 ? 1 414 
2 1 9HZ1 B 1 ? 414 ? A0A806EKD1 1 ? 414 ? 1 414 
3 1 9HZ1 C 1 ? 414 ? A0A806EKD1 1 ? 414 ? 1 414 
4 1 9HZ1 D 1 ? 414 ? A0A806EKD1 1 ? 414 ? 1 414 
5 1 9HZ1 E 1 ? 414 ? A0A806EKD1 1 ? 414 ? 1 414 
6 1 9HZ1 F 1 ? 414 ? A0A806EKD1 1 ? 414 ? 1 414 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9HZ1 SER A 196 ? UNP A0A806EKD1 ASN 196 conflict 196 1  
1 9HZ1 MET A 261 ? UNP A0A806EKD1 VAL 261 conflict 261 2  
1 9HZ1 LYS A 346 ? UNP A0A806EKD1 ASN 346 conflict 346 3  
2 9HZ1 SER B 196 ? UNP A0A806EKD1 ASN 196 conflict 196 4  
2 9HZ1 MET B 261 ? UNP A0A806EKD1 VAL 261 conflict 261 5  
2 9HZ1 LYS B 346 ? UNP A0A806EKD1 ASN 346 conflict 346 6  
3 9HZ1 SER C 196 ? UNP A0A806EKD1 ASN 196 conflict 196 7  
3 9HZ1 MET C 261 ? UNP A0A806EKD1 VAL 261 conflict 261 8  
3 9HZ1 LYS C 346 ? UNP A0A806EKD1 ASN 346 conflict 346 9  
4 9HZ1 SER D 196 ? UNP A0A806EKD1 ASN 196 conflict 196 10 
4 9HZ1 MET D 261 ? UNP A0A806EKD1 VAL 261 conflict 261 11 
4 9HZ1 LYS D 346 ? UNP A0A806EKD1 ASN 346 conflict 346 12 
5 9HZ1 SER E 196 ? UNP A0A806EKD1 ASN 196 conflict 196 13 
5 9HZ1 MET E 261 ? UNP A0A806EKD1 VAL 261 conflict 261 14 
5 9HZ1 LYS E 346 ? UNP A0A806EKD1 ASN 346 conflict 346 15 
6 9HZ1 SER F 196 ? UNP A0A806EKD1 ASN 196 conflict 196 16 
6 9HZ1 MET F 261 ? UNP A0A806EKD1 VAL 261 conflict 261 17 
6 9HZ1 LYS F 346 ? UNP A0A806EKD1 ASN 346 conflict 346 18 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? tetrameric 4 
2 author_defined_assembly ? tetrameric 4 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 10200 ? 
1 MORE         -59   ? 
1 'SSA (A^2)'  62560 ? 
2 'ABSA (A^2)' 10030 ? 
2 MORE         -57   ? 
2 'SSA (A^2)'  62420 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1   A,B,C,D,G,H,I,J,M,N,O,P 
2 1,2 E,F,K,L,Q,R             
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'light scattering' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z         1.0000000000  0.0000000000 0.0000000000 0.0000000000    0.0000000000 
1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000   
2 'crystal symmetry operation' 3_454 -x-1,y,-z-1/2 -1.0000000000 0.0000000000 0.0000000000 -167.8320000000 0.0000000000 
1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 -87.6340000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LEU A 5   ? ASP A 13  ? LEU A 5   ASP A 13  1 ? 9  
HELX_P HELX_P2  AA2 GLY A 23  ? MET A 28  ? GLY A 23  MET A 28  5 ? 6  
HELX_P HELX_P3  AA3 TRP A 33  ? HIS A 38  ? TRP A 33  HIS A 38  1 ? 6  
HELX_P HELX_P4  AA4 ASN A 41  ? GLN A 47  ? ASN A 41  GLN A 47  1 ? 7  
HELX_P HELX_P5  AA5 LEU A 48  ? PHE A 52  ? LEU A 48  PHE A 52  5 ? 5  
HELX_P HELX_P6  AA6 ASP A 58  ? VAL A 69  ? ASP A 58  VAL A 69  1 ? 12 
HELX_P HELX_P7  AA7 ASP A 96  ? ALA A 100 ? ASP A 96  ALA A 100 5 ? 5  
HELX_P HELX_P8  AA8 ASP A 105 ? GLU A 117 ? ASP A 105 GLU A 117 1 ? 13 
HELX_P HELX_P9  AA9 PRO A 133 ? ASP A 138 ? PRO A 133 ASP A 138 1 ? 6  
HELX_P HELX_P10 AB1 ASP A 138 ? ASN A 156 ? ASP A 138 ASN A 156 1 ? 19 
HELX_P HELX_P11 AB2 GLY A 167 ? LYS A 172 ? GLY A 167 LYS A 172 5 ? 6  
HELX_P HELX_P12 AB3 HIS A 177 ? GLN A 189 ? HIS A 177 GLN A 189 1 ? 13 
HELX_P HELX_P13 AB4 SER A 257 ? ILE A 271 ? SER A 257 ILE A 271 1 ? 15 
HELX_P HELX_P14 AB5 PRO A 288 ? TYR A 310 ? PRO A 288 TYR A 310 1 ? 23 
HELX_P HELX_P15 AB6 LEU B 5   ? ASP B 13  ? LEU B 5   ASP B 13  1 ? 9  
HELX_P HELX_P16 AB7 GLY B 23  ? MET B 28  ? GLY B 23  MET B 28  5 ? 6  
HELX_P HELX_P17 AB8 TRP B 33  ? HIS B 38  ? TRP B 33  HIS B 38  1 ? 6  
HELX_P HELX_P18 AB9 ASN B 41  ? GLN B 47  ? ASN B 41  GLN B 47  1 ? 7  
HELX_P HELX_P19 AC1 LEU B 48  ? PHE B 52  ? LEU B 48  PHE B 52  5 ? 5  
HELX_P HELX_P20 AC2 ASP B 58  ? VAL B 69  ? ASP B 58  VAL B 69  1 ? 12 
HELX_P HELX_P21 AC3 ASP B 96  ? ALA B 100 ? ASP B 96  ALA B 100 5 ? 5  
HELX_P HELX_P22 AC4 ASP B 105 ? GLU B 117 ? ASP B 105 GLU B 117 1 ? 13 
HELX_P HELX_P23 AC5 PRO B 133 ? ASP B 138 ? PRO B 133 ASP B 138 1 ? 6  
HELX_P HELX_P24 AC6 ASP B 138 ? ASN B 156 ? ASP B 138 ASN B 156 1 ? 19 
HELX_P HELX_P25 AC7 GLY B 167 ? LYS B 172 ? GLY B 167 LYS B 172 5 ? 6  
HELX_P HELX_P26 AC8 HIS B 177 ? GLN B 189 ? HIS B 177 GLN B 189 1 ? 13 
HELX_P HELX_P27 AC9 SER B 257 ? ILE B 271 ? SER B 257 ILE B 271 1 ? 15 
HELX_P HELX_P28 AD1 PRO B 288 ? TYR B 310 ? PRO B 288 TYR B 310 1 ? 23 
HELX_P HELX_P29 AD2 LEU C 5   ? ASP C 13  ? LEU C 5   ASP C 13  1 ? 9  
HELX_P HELX_P30 AD3 GLY C 23  ? MET C 28  ? GLY C 23  MET C 28  5 ? 6  
HELX_P HELX_P31 AD4 TRP C 33  ? HIS C 38  ? TRP C 33  HIS C 38  1 ? 6  
HELX_P HELX_P32 AD5 ASN C 41  ? GLN C 47  ? ASN C 41  GLN C 47  1 ? 7  
HELX_P HELX_P33 AD6 LEU C 48  ? PHE C 52  ? LEU C 48  PHE C 52  5 ? 5  
HELX_P HELX_P34 AD7 ASP C 58  ? VAL C 69  ? ASP C 58  VAL C 69  1 ? 12 
HELX_P HELX_P35 AD8 ASP C 96  ? ALA C 100 ? ASP C 96  ALA C 100 5 ? 5  
HELX_P HELX_P36 AD9 ASP C 105 ? GLU C 117 ? ASP C 105 GLU C 117 1 ? 13 
HELX_P HELX_P37 AE1 PRO C 133 ? ASP C 138 ? PRO C 133 ASP C 138 1 ? 6  
HELX_P HELX_P38 AE2 ASP C 138 ? ASN C 156 ? ASP C 138 ASN C 156 1 ? 19 
HELX_P HELX_P39 AE3 ASN C 168 ? LYS C 172 ? ASN C 168 LYS C 172 5 ? 5  
HELX_P HELX_P40 AE4 HIS C 177 ? GLN C 189 ? HIS C 177 GLN C 189 1 ? 13 
HELX_P HELX_P41 AE5 SER C 257 ? ILE C 271 ? SER C 257 ILE C 271 1 ? 15 
HELX_P HELX_P42 AE6 PRO C 288 ? TYR C 310 ? PRO C 288 TYR C 310 1 ? 23 
HELX_P HELX_P43 AE7 LEU D 5   ? ASP D 13  ? LEU D 5   ASP D 13  1 ? 9  
HELX_P HELX_P44 AE8 GLY D 23  ? MET D 28  ? GLY D 23  MET D 28  5 ? 6  
HELX_P HELX_P45 AE9 TRP D 33  ? HIS D 38  ? TRP D 33  HIS D 38  1 ? 6  
HELX_P HELX_P46 AF1 ASN D 41  ? GLN D 47  ? ASN D 41  GLN D 47  1 ? 7  
HELX_P HELX_P47 AF2 LEU D 48  ? PHE D 52  ? LEU D 48  PHE D 52  5 ? 5  
HELX_P HELX_P48 AF3 ASP D 58  ? VAL D 69  ? ASP D 58  VAL D 69  1 ? 12 
HELX_P HELX_P49 AF4 ASP D 96  ? ALA D 100 ? ASP D 96  ALA D 100 5 ? 5  
HELX_P HELX_P50 AF5 ASP D 105 ? GLU D 117 ? ASP D 105 GLU D 117 1 ? 13 
HELX_P HELX_P51 AF6 PRO D 133 ? ASP D 138 ? PRO D 133 ASP D 138 1 ? 6  
HELX_P HELX_P52 AF7 ASP D 138 ? ASN D 156 ? ASP D 138 ASN D 156 1 ? 19 
HELX_P HELX_P53 AF8 GLY D 167 ? LYS D 172 ? GLY D 167 LYS D 172 5 ? 6  
HELX_P HELX_P54 AF9 HIS D 177 ? GLN D 189 ? HIS D 177 GLN D 189 1 ? 13 
HELX_P HELX_P55 AG1 SER D 257 ? ILE D 271 ? SER D 257 ILE D 271 1 ? 15 
HELX_P HELX_P56 AG2 PRO D 288 ? TYR D 310 ? PRO D 288 TYR D 310 1 ? 23 
HELX_P HELX_P57 AG3 LEU E 5   ? ASP E 13  ? LEU E 5   ASP E 13  1 ? 9  
HELX_P HELX_P58 AG4 GLY E 23  ? MET E 28  ? GLY E 23  MET E 28  5 ? 6  
HELX_P HELX_P59 AG5 TRP E 33  ? HIS E 38  ? TRP E 33  HIS E 38  1 ? 6  
HELX_P HELX_P60 AG6 ASN E 41  ? GLN E 47  ? ASN E 41  GLN E 47  1 ? 7  
HELX_P HELX_P61 AG7 LEU E 48  ? PHE E 52  ? LEU E 48  PHE E 52  5 ? 5  
HELX_P HELX_P62 AG8 ASP E 58  ? VAL E 69  ? ASP E 58  VAL E 69  1 ? 12 
HELX_P HELX_P63 AG9 ASP E 96  ? ALA E 100 ? ASP E 96  ALA E 100 5 ? 5  
HELX_P HELX_P64 AH1 ASP E 105 ? GLU E 117 ? ASP E 105 GLU E 117 1 ? 13 
HELX_P HELX_P65 AH2 PRO E 133 ? ASP E 138 ? PRO E 133 ASP E 138 1 ? 6  
HELX_P HELX_P66 AH3 ASP E 138 ? ASN E 156 ? ASP E 138 ASN E 156 1 ? 19 
HELX_P HELX_P67 AH4 GLY E 167 ? LYS E 172 ? GLY E 167 LYS E 172 5 ? 6  
HELX_P HELX_P68 AH5 HIS E 177 ? GLN E 189 ? HIS E 177 GLN E 189 1 ? 13 
HELX_P HELX_P69 AH6 SER E 257 ? ILE E 271 ? SER E 257 ILE E 271 1 ? 15 
HELX_P HELX_P70 AH7 PRO E 288 ? TYR E 310 ? PRO E 288 TYR E 310 1 ? 23 
HELX_P HELX_P71 AH8 LEU F 5   ? ASP F 13  ? LEU F 5   ASP F 13  1 ? 9  
HELX_P HELX_P72 AH9 GLY F 23  ? MET F 28  ? GLY F 23  MET F 28  5 ? 6  
HELX_P HELX_P73 AI1 TRP F 33  ? HIS F 38  ? TRP F 33  HIS F 38  1 ? 6  
HELX_P HELX_P74 AI2 ASN F 41  ? GLN F 47  ? ASN F 41  GLN F 47  1 ? 7  
HELX_P HELX_P75 AI3 LEU F 48  ? PHE F 52  ? LEU F 48  PHE F 52  5 ? 5  
HELX_P HELX_P76 AI4 ASP F 58  ? VAL F 69  ? ASP F 58  VAL F 69  1 ? 12 
HELX_P HELX_P77 AI5 ASP F 96  ? ALA F 100 ? ASP F 96  ALA F 100 5 ? 5  
HELX_P HELX_P78 AI6 ASP F 105 ? GLU F 117 ? ASP F 105 GLU F 117 1 ? 13 
HELX_P HELX_P79 AI7 PRO F 133 ? ASP F 138 ? PRO F 133 ASP F 138 1 ? 6  
HELX_P HELX_P80 AI8 ASP F 138 ? ASN F 156 ? ASP F 138 ASN F 156 1 ? 19 
HELX_P HELX_P81 AI9 GLY F 167 ? LYS F 172 ? GLY F 167 LYS F 172 5 ? 6  
HELX_P HELX_P82 AJ1 HIS F 177 ? GLN F 189 ? HIS F 177 GLN F 189 1 ? 13 
HELX_P HELX_P83 AJ2 SER F 257 ? ILE F 271 ? SER F 257 ILE F 271 1 ? 15 
HELX_P HELX_P84 AJ3 PRO F 288 ? TYR F 310 ? PRO F 288 TYR F 310 1 ? 23 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 9 ? 
AA2 ? 2 ? 
AA3 ? 5 ? 
AA4 ? 4 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
AA7 ? 9 ? 
AA8 ? 5 ? 
AA9 ? 4 ? 
AB1 ? 2 ? 
AB2 ? 9 ? 
AB3 ? 2 ? 
AB4 ? 5 ? 
AB5 ? 4 ? 
AB6 ? 2 ? 
AB7 ? 2 ? 
AB8 ? 9 ? 
AB9 ? 5 ? 
AC1 ? 4 ? 
AC2 ? 2 ? 
AC3 ? 9 ? 
AC4 ? 2 ? 
AC5 ? 5 ? 
AC6 ? 4 ? 
AC7 ? 2 ? 
AC8 ? 2 ? 
AC9 ? 9 ? 
AD1 ? 4 ? 
AD2 ? 4 ? 
AD3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA1 7 8 ? parallel      
AA1 8 9 ? parallel      
AA2 1 2 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? parallel      
AA6 1 2 ? parallel      
AA7 1 2 ? parallel      
AA7 2 3 ? parallel      
AA7 3 4 ? parallel      
AA7 4 5 ? parallel      
AA7 5 6 ? parallel      
AA7 6 7 ? parallel      
AA7 7 8 ? parallel      
AA7 8 9 ? parallel      
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB2 1 2 ? parallel      
AB2 2 3 ? parallel      
AB2 3 4 ? parallel      
AB2 4 5 ? parallel      
AB2 5 6 ? parallel      
AB2 6 7 ? parallel      
AB2 7 8 ? parallel      
AB2 8 9 ? parallel      
AB3 1 2 ? parallel      
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? parallel      
AB7 1 2 ? parallel      
AB8 1 2 ? parallel      
AB8 2 3 ? parallel      
AB8 3 4 ? parallel      
AB8 4 5 ? parallel      
AB8 5 6 ? parallel      
AB8 6 7 ? parallel      
AB8 7 8 ? parallel      
AB8 8 9 ? parallel      
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AB9 4 5 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC2 1 2 ? parallel      
AC3 1 2 ? parallel      
AC3 2 3 ? parallel      
AC3 3 4 ? parallel      
AC3 4 5 ? parallel      
AC3 5 6 ? parallel      
AC3 6 7 ? parallel      
AC3 7 8 ? parallel      
AC3 8 9 ? parallel      
AC4 1 2 ? parallel      
AC5 1 2 ? anti-parallel 
AC5 2 3 ? anti-parallel 
AC5 3 4 ? anti-parallel 
AC5 4 5 ? anti-parallel 
AC6 1 2 ? anti-parallel 
AC6 2 3 ? anti-parallel 
AC6 3 4 ? anti-parallel 
AC7 1 2 ? parallel      
AC8 1 2 ? parallel      
AC9 1 2 ? parallel      
AC9 2 3 ? parallel      
AC9 3 4 ? parallel      
AC9 4 5 ? parallel      
AC9 5 6 ? parallel      
AC9 6 7 ? parallel      
AC9 7 8 ? parallel      
AC9 8 9 ? parallel      
AD1 1 2 ? anti-parallel 
AD1 2 3 ? anti-parallel 
AD1 3 4 ? anti-parallel 
AD2 1 2 ? anti-parallel 
AD2 2 3 ? anti-parallel 
AD2 3 4 ? anti-parallel 
AD3 1 2 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 16  ? HIS A 21  ? LEU A 16  HIS A 21  
AA1 2 TYR A 73  ? LYS A 79  ? TYR A 73  LYS A 79  
AA1 3 LEU A 120 ? ALA A 126 ? LEU A 120 ALA A 126 
AA1 4 GLY A 162 ? ASP A 166 ? GLY A 162 ASP A 166 
AA1 5 ILE A 193 ? SER A 196 ? ILE A 193 SER A 196 
AA1 6 VAL A 213 ? THR A 215 ? VAL A 213 THR A 215 
AA1 7 ALA A 235 ? THR A 241 ? ALA A 235 THR A 241 
AA1 8 ASN A 274 ? GLY A 280 ? ASN A 274 GLY A 280 
AA1 9 LEU A 16  ? HIS A 21  ? LEU A 16  HIS A 21  
AA2 1 ASN A 251 ? ASP A 252 ? ASN A 251 ASP A 252 
AA2 2 SER B 402 ? ASP B 403 ? SER B 402 ASP B 403 
AA3 1 ARG A 313 ? PRO A 314 ? ARG A 313 PRO A 314 
AA3 2 PHE A 326 ? HIS A 329 ? PHE A 326 HIS A 329 
AA3 3 ASP A 334 ? ILE A 338 ? ASP A 334 ILE A 338 
AA3 4 ARG A 407 ? TYR A 413 ? ARG A 407 TYR A 413 
AA3 5 ILE A 368 ? TRP A 373 ? ILE A 368 TRP A 373 
AA4 1 THR A 318 ? SER A 319 ? THR A 318 SER A 319 
AA4 2 PRO A 358 ? VAL A 362 ? PRO A 358 VAL A 362 
AA4 3 VAL A 390 ? ASP A 394 ? VAL A 390 ASP A 394 
AA4 4 PHE A 382 ? ASP A 385 ? PHE A 382 ASP A 385 
AA5 1 VAL A 343 ? VAL A 344 ? VAL A 343 VAL A 344 
AA5 2 TYR A 398 ? PRO A 399 ? TYR A 398 PRO A 399 
AA6 1 SER A 402 ? ASP A 403 ? SER A 402 ASP A 403 
AA6 2 ASN B 251 ? ASP B 252 ? ASN B 251 ASP B 252 
AA7 1 LEU B 16  ? HIS B 21  ? LEU B 16  HIS B 21  
AA7 2 TYR B 73  ? LYS B 79  ? TYR B 73  LYS B 79  
AA7 3 LEU B 120 ? ALA B 126 ? LEU B 120 ALA B 126 
AA7 4 GLY B 162 ? ASP B 166 ? GLY B 162 ASP B 166 
AA7 5 ILE B 193 ? SER B 196 ? ILE B 193 SER B 196 
AA7 6 VAL B 213 ? THR B 215 ? VAL B 213 THR B 215 
AA7 7 ALA B 235 ? THR B 241 ? ALA B 235 THR B 241 
AA7 8 ASN B 274 ? GLY B 280 ? ASN B 274 GLY B 280 
AA7 9 LEU B 16  ? HIS B 21  ? LEU B 16  HIS B 21  
AA8 1 ARG B 313 ? PRO B 314 ? ARG B 313 PRO B 314 
AA8 2 PHE B 326 ? HIS B 329 ? PHE B 326 HIS B 329 
AA8 3 ASP B 334 ? LEU B 339 ? ASP B 334 LEU B 339 
AA8 4 VAL B 406 ? TYR B 413 ? VAL B 406 TYR B 413 
AA8 5 ILE B 368 ? TRP B 373 ? ILE B 368 TRP B 373 
AA9 1 THR B 318 ? SER B 319 ? THR B 318 SER B 319 
AA9 2 PRO B 358 ? VAL B 362 ? PRO B 358 VAL B 362 
AA9 3 VAL B 390 ? ASP B 394 ? VAL B 390 ASP B 394 
AA9 4 PHE B 382 ? ASP B 385 ? PHE B 382 ASP B 385 
AB1 1 VAL B 343 ? VAL B 344 ? VAL B 343 VAL B 344 
AB1 2 TYR B 398 ? PRO B 399 ? TYR B 398 PRO B 399 
AB2 1 LEU C 16  ? HIS C 21  ? LEU C 16  HIS C 21  
AB2 2 TYR C 73  ? LYS C 79  ? TYR C 73  LYS C 79  
AB2 3 LEU C 120 ? ALA C 126 ? LEU C 120 ALA C 126 
AB2 4 GLY C 162 ? ASP C 166 ? GLY C 162 ASP C 166 
AB2 5 ILE C 193 ? ASN C 197 ? ILE C 193 ASN C 197 
AB2 6 VAL C 213 ? THR C 215 ? VAL C 213 THR C 215 
AB2 7 ALA C 235 ? THR C 241 ? ALA C 235 THR C 241 
AB2 8 ASN C 274 ? GLY C 280 ? ASN C 274 GLY C 280 
AB2 9 LEU C 16  ? HIS C 21  ? LEU C 16  HIS C 21  
AB3 1 ASN C 251 ? ASP C 252 ? ASN C 251 ASP C 252 
AB3 2 SER D 402 ? ASP D 403 ? SER D 402 ASP D 403 
AB4 1 ARG C 313 ? PRO C 314 ? ARG C 313 PRO C 314 
AB4 2 PHE C 326 ? HIS C 329 ? PHE C 326 HIS C 329 
AB4 3 ASP C 334 ? ILE C 338 ? ASP C 334 ILE C 338 
AB4 4 ARG C 407 ? TYR C 413 ? ARG C 407 TYR C 413 
AB4 5 ILE C 368 ? TRP C 373 ? ILE C 368 TRP C 373 
AB5 1 THR C 318 ? SER C 319 ? THR C 318 SER C 319 
AB5 2 PRO C 358 ? VAL C 362 ? PRO C 358 VAL C 362 
AB5 3 VAL C 390 ? ASP C 394 ? VAL C 390 ASP C 394 
AB5 4 PHE C 382 ? ASP C 385 ? PHE C 382 ASP C 385 
AB6 1 VAL C 343 ? VAL C 344 ? VAL C 343 VAL C 344 
AB6 2 TYR C 398 ? PRO C 399 ? TYR C 398 PRO C 399 
AB7 1 SER C 402 ? ASP C 403 ? SER C 402 ASP C 403 
AB7 2 ASN D 251 ? ASP D 252 ? ASN D 251 ASP D 252 
AB8 1 LEU D 16  ? HIS D 21  ? LEU D 16  HIS D 21  
AB8 2 TYR D 73  ? LYS D 79  ? TYR D 73  LYS D 79  
AB8 3 LEU D 120 ? ALA D 126 ? LEU D 120 ALA D 126 
AB8 4 GLY D 162 ? ASP D 166 ? GLY D 162 ASP D 166 
AB8 5 ILE D 193 ? SER D 196 ? ILE D 193 SER D 196 
AB8 6 VAL D 213 ? THR D 215 ? VAL D 213 THR D 215 
AB8 7 ALA D 235 ? THR D 241 ? ALA D 235 THR D 241 
AB8 8 ASN D 274 ? GLY D 280 ? ASN D 274 GLY D 280 
AB8 9 LEU D 16  ? HIS D 21  ? LEU D 16  HIS D 21  
AB9 1 ARG D 313 ? PRO D 314 ? ARG D 313 PRO D 314 
AB9 2 PHE D 326 ? HIS D 329 ? PHE D 326 HIS D 329 
AB9 3 ASP D 334 ? LEU D 339 ? ASP D 334 LEU D 339 
AB9 4 VAL D 406 ? TYR D 413 ? VAL D 406 TYR D 413 
AB9 5 ILE D 368 ? TRP D 373 ? ILE D 368 TRP D 373 
AC1 1 THR D 318 ? SER D 319 ? THR D 318 SER D 319 
AC1 2 PRO D 358 ? VAL D 362 ? PRO D 358 VAL D 362 
AC1 3 VAL D 390 ? ASP D 394 ? VAL D 390 ASP D 394 
AC1 4 PHE D 382 ? ASP D 385 ? PHE D 382 ASP D 385 
AC2 1 VAL D 343 ? VAL D 344 ? VAL D 343 VAL D 344 
AC2 2 TYR D 398 ? PRO D 399 ? TYR D 398 PRO D 399 
AC3 1 LEU E 16  ? HIS E 21  ? LEU E 16  HIS E 21  
AC3 2 TYR E 73  ? LYS E 79  ? TYR E 73  LYS E 79  
AC3 3 LEU E 120 ? ALA E 126 ? LEU E 120 ALA E 126 
AC3 4 GLY E 162 ? ASP E 166 ? GLY E 162 ASP E 166 
AC3 5 ILE E 193 ? SER E 196 ? ILE E 193 SER E 196 
AC3 6 VAL E 213 ? THR E 215 ? VAL E 213 THR E 215 
AC3 7 ALA E 235 ? THR E 241 ? ALA E 235 THR E 241 
AC3 8 ASN E 274 ? GLY E 280 ? ASN E 274 GLY E 280 
AC3 9 LEU E 16  ? HIS E 21  ? LEU E 16  HIS E 21  
AC4 1 ASN E 251 ? ASP E 252 ? ASN E 251 ASP E 252 
AC4 2 SER F 402 ? ASP F 403 ? SER F 402 ASP F 403 
AC5 1 ARG E 313 ? PRO E 314 ? ARG E 313 PRO E 314 
AC5 2 PHE E 326 ? HIS E 329 ? PHE E 326 HIS E 329 
AC5 3 ASP E 334 ? ILE E 338 ? ASP E 334 ILE E 338 
AC5 4 ARG E 407 ? TYR E 413 ? ARG E 407 TYR E 413 
AC5 5 ILE E 368 ? TRP E 373 ? ILE E 368 TRP E 373 
AC6 1 THR E 318 ? SER E 319 ? THR E 318 SER E 319 
AC6 2 PRO E 358 ? VAL E 362 ? PRO E 358 VAL E 362 
AC6 3 VAL E 390 ? ASP E 394 ? VAL E 390 ASP E 394 
AC6 4 PHE E 382 ? ASP E 385 ? PHE E 382 ASP E 385 
AC7 1 VAL E 343 ? VAL E 344 ? VAL E 343 VAL E 344 
AC7 2 TYR E 398 ? PRO E 399 ? TYR E 398 PRO E 399 
AC8 1 SER E 402 ? ASP E 403 ? SER E 402 ASP E 403 
AC8 2 ASN F 251 ? ASP F 252 ? ASN F 251 ASP F 252 
AC9 1 LEU F 16  ? HIS F 21  ? LEU F 16  HIS F 21  
AC9 2 TYR F 73  ? LYS F 79  ? TYR F 73  LYS F 79  
AC9 3 LEU F 120 ? ALA F 126 ? LEU F 120 ALA F 126 
AC9 4 GLY F 162 ? ASP F 166 ? GLY F 162 ASP F 166 
AC9 5 ILE F 193 ? SER F 196 ? ILE F 193 SER F 196 
AC9 6 VAL F 213 ? THR F 215 ? VAL F 213 THR F 215 
AC9 7 ALA F 235 ? THR F 241 ? ALA F 235 THR F 241 
AC9 8 ASN F 274 ? GLY F 280 ? ASN F 274 GLY F 280 
AC9 9 LEU F 16  ? HIS F 21  ? LEU F 16  HIS F 21  
AD1 1 THR F 318 ? SER F 319 ? THR F 318 SER F 319 
AD1 2 PRO F 358 ? VAL F 362 ? PRO F 358 VAL F 362 
AD1 3 VAL F 390 ? ASP F 394 ? VAL F 390 ASP F 394 
AD1 4 PHE F 382 ? ASP F 385 ? PHE F 382 ASP F 385 
AD2 1 PHE F 326 ? HIS F 329 ? PHE F 326 HIS F 329 
AD2 2 ASP F 334 ? LEU F 339 ? ASP F 334 LEU F 339 
AD2 3 VAL F 406 ? TYR F 413 ? VAL F 406 TYR F 413 
AD2 4 ILE F 368 ? TRP F 373 ? ILE F 368 TRP F 373 
AD3 1 VAL F 343 ? VAL F 344 ? VAL F 343 VAL F 344 
AD3 2 TYR F 398 ? PRO F 399 ? TYR F 398 PRO F 399 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 20  ? N ILE A 20  O VAL A 75  ? O VAL A 75  
AA1 2 3 N LEU A 76  ? N LEU A 76  O TYR A 124 ? O TYR A 124 
AA1 3 4 N PHE A 123 ? N PHE A 123 O TRP A 164 ? O TRP A 164 
AA1 4 5 N PHE A 163 ? N PHE A 163 O VAL A 195 ? O VAL A 195 
AA1 5 6 N SER A 196 ? N SER A 196 O VAL A 213 ? O VAL A 213 
AA1 6 7 N VAL A 214 ? N VAL A 214 O ALA A 235 ? O ALA A 235 
AA1 7 8 N ILE A 240 ? N ILE A 240 O ASN A 278 ? O ASN A 278 
AA1 8 9 O ILE A 279 ? O ILE A 279 N PHE A 19  ? N PHE A 19  
AA2 1 2 N ASN A 251 ? N ASN A 251 O ASP B 403 ? O ASP B 403 
AA3 1 2 N ARG A 313 ? N ARG A 313 O HIS A 329 ? O HIS A 329 
AA3 2 3 N PHE A 326 ? N PHE A 326 O CYS A 337 ? O CYS A 337 
AA3 3 4 N ILE A 338 ? N ILE A 338 O ARG A 407 ? O ARG A 407 
AA3 4 5 O ASP A 412 ? O ASP A 412 N ARG A 370 ? N ARG A 370 
AA4 1 2 N THR A 318 ? N THR A 318 O VAL A 362 ? O VAL A 362 
AA4 2 3 N ARG A 359 ? N ARG A 359 O VAL A 393 ? O VAL A 393 
AA4 3 4 O THR A 392 ? O THR A 392 N THR A 383 ? N THR A 383 
AA5 1 2 N VAL A 344 ? N VAL A 344 O TYR A 398 ? O TYR A 398 
AA6 1 2 N ASP A 403 ? N ASP A 403 O ASN B 251 ? O ASN B 251 
AA7 1 2 N ILE B 20  ? N ILE B 20  O VAL B 75  ? O VAL B 75  
AA7 2 3 N LEU B 76  ? N LEU B 76  O TYR B 124 ? O TYR B 124 
AA7 3 4 N PHE B 123 ? N PHE B 123 O TRP B 164 ? O TRP B 164 
AA7 4 5 N PHE B 163 ? N PHE B 163 O VAL B 195 ? O VAL B 195 
AA7 5 6 N SER B 196 ? N SER B 196 O VAL B 213 ? O VAL B 213 
AA7 6 7 N VAL B 214 ? N VAL B 214 O ALA B 235 ? O ALA B 235 
AA7 7 8 N ILE B 240 ? N ILE B 240 O ASN B 278 ? O ASN B 278 
AA7 8 9 O ILE B 279 ? O ILE B 279 N PHE B 19  ? N PHE B 19  
AA8 1 2 N ARG B 313 ? N ARG B 313 O HIS B 329 ? O HIS B 329 
AA8 2 3 N PHE B 326 ? N PHE B 326 O CYS B 337 ? O CYS B 337 
AA8 3 4 N ILE B 338 ? N ILE B 338 O ARG B 407 ? O ARG B 407 
AA8 4 5 O ASP B 412 ? O ASP B 412 N ARG B 370 ? N ARG B 370 
AA9 1 2 N THR B 318 ? N THR B 318 O VAL B 362 ? O VAL B 362 
AA9 2 3 N ARG B 359 ? N ARG B 359 O VAL B 393 ? O VAL B 393 
AA9 3 4 O THR B 392 ? O THR B 392 N THR B 383 ? N THR B 383 
AB1 1 2 N VAL B 344 ? N VAL B 344 O TYR B 398 ? O TYR B 398 
AB2 1 2 N ILE C 20  ? N ILE C 20  O VAL C 75  ? O VAL C 75  
AB2 2 3 N LEU C 76  ? N LEU C 76  O TYR C 124 ? O TYR C 124 
AB2 3 4 N PHE C 123 ? N PHE C 123 O TRP C 164 ? O TRP C 164 
AB2 4 5 N PHE C 163 ? N PHE C 163 O VAL C 195 ? O VAL C 195 
AB2 5 6 N SER C 196 ? N SER C 196 O VAL C 213 ? O VAL C 213 
AB2 6 7 N VAL C 214 ? N VAL C 214 O ALA C 235 ? O ALA C 235 
AB2 7 8 N ILE C 240 ? N ILE C 240 O ASN C 278 ? O ASN C 278 
AB2 8 9 O ILE C 279 ? O ILE C 279 N PHE C 19  ? N PHE C 19  
AB3 1 2 N ASN C 251 ? N ASN C 251 O ASP D 403 ? O ASP D 403 
AB4 1 2 N ARG C 313 ? N ARG C 313 O HIS C 329 ? O HIS C 329 
AB4 2 3 N PHE C 326 ? N PHE C 326 O CYS C 337 ? O CYS C 337 
AB4 3 4 N ILE C 338 ? N ILE C 338 O ARG C 407 ? O ARG C 407 
AB4 4 5 O ASP C 412 ? O ASP C 412 N ARG C 370 ? N ARG C 370 
AB5 1 2 N THR C 318 ? N THR C 318 O VAL C 362 ? O VAL C 362 
AB5 2 3 N ARG C 359 ? N ARG C 359 O VAL C 393 ? O VAL C 393 
AB5 3 4 O VAL C 390 ? O VAL C 390 N ASP C 385 ? N ASP C 385 
AB6 1 2 N VAL C 344 ? N VAL C 344 O TYR C 398 ? O TYR C 398 
AB7 1 2 N ASP C 403 ? N ASP C 403 O ASN D 251 ? O ASN D 251 
AB8 1 2 N ILE D 20  ? N ILE D 20  O VAL D 75  ? O VAL D 75  
AB8 2 3 N LEU D 76  ? N LEU D 76  O TYR D 124 ? O TYR D 124 
AB8 3 4 N PHE D 123 ? N PHE D 123 O TRP D 164 ? O TRP D 164 
AB8 4 5 N PHE D 163 ? N PHE D 163 O VAL D 195 ? O VAL D 195 
AB8 5 6 N SER D 196 ? N SER D 196 O VAL D 213 ? O VAL D 213 
AB8 6 7 N VAL D 214 ? N VAL D 214 O ALA D 235 ? O ALA D 235 
AB8 7 8 N ILE D 240 ? N ILE D 240 O ASN D 278 ? O ASN D 278 
AB8 8 9 O ILE D 279 ? O ILE D 279 N PHE D 19  ? N PHE D 19  
AB9 1 2 N ARG D 313 ? N ARG D 313 O HIS D 329 ? O HIS D 329 
AB9 2 3 N PHE D 326 ? N PHE D 326 O CYS D 337 ? O CYS D 337 
AB9 3 4 N ILE D 338 ? N ILE D 338 O ARG D 407 ? O ARG D 407 
AB9 4 5 O ASP D 412 ? O ASP D 412 N ARG D 370 ? N ARG D 370 
AC1 1 2 N THR D 318 ? N THR D 318 O VAL D 362 ? O VAL D 362 
AC1 2 3 N ARG D 359 ? N ARG D 359 O VAL D 393 ? O VAL D 393 
AC1 3 4 O THR D 392 ? O THR D 392 N THR D 383 ? N THR D 383 
AC2 1 2 N VAL D 344 ? N VAL D 344 O TYR D 398 ? O TYR D 398 
AC3 1 2 N ILE E 20  ? N ILE E 20  O VAL E 75  ? O VAL E 75  
AC3 2 3 N LEU E 76  ? N LEU E 76  O TYR E 124 ? O TYR E 124 
AC3 3 4 N PHE E 123 ? N PHE E 123 O TRP E 164 ? O TRP E 164 
AC3 4 5 N PHE E 163 ? N PHE E 163 O VAL E 195 ? O VAL E 195 
AC3 5 6 N SER E 196 ? N SER E 196 O VAL E 213 ? O VAL E 213 
AC3 6 7 N VAL E 214 ? N VAL E 214 O ALA E 235 ? O ALA E 235 
AC3 7 8 N ILE E 240 ? N ILE E 240 O ASN E 278 ? O ASN E 278 
AC3 8 9 O ILE E 279 ? O ILE E 279 N PHE E 19  ? N PHE E 19  
AC4 1 2 N ASN E 251 ? N ASN E 251 O ASP F 403 ? O ASP F 403 
AC5 1 2 N ARG E 313 ? N ARG E 313 O HIS E 329 ? O HIS E 329 
AC5 2 3 N PHE E 326 ? N PHE E 326 O CYS E 337 ? O CYS E 337 
AC5 3 4 N ILE E 338 ? N ILE E 338 O ARG E 407 ? O ARG E 407 
AC5 4 5 O ASP E 412 ? O ASP E 412 N ARG E 370 ? N ARG E 370 
AC6 1 2 N THR E 318 ? N THR E 318 O VAL E 362 ? O VAL E 362 
AC6 2 3 N ARG E 359 ? N ARG E 359 O VAL E 393 ? O VAL E 393 
AC6 3 4 O THR E 392 ? O THR E 392 N THR E 383 ? N THR E 383 
AC7 1 2 N VAL E 344 ? N VAL E 344 O TYR E 398 ? O TYR E 398 
AC8 1 2 N ASP E 403 ? N ASP E 403 O ASN F 251 ? O ASN F 251 
AC9 1 2 N ILE F 20  ? N ILE F 20  O VAL F 75  ? O VAL F 75  
AC9 2 3 N LEU F 76  ? N LEU F 76  O TYR F 124 ? O TYR F 124 
AC9 3 4 N PHE F 123 ? N PHE F 123 O TRP F 164 ? O TRP F 164 
AC9 4 5 N PHE F 163 ? N PHE F 163 O VAL F 195 ? O VAL F 195 
AC9 5 6 N SER F 196 ? N SER F 196 O VAL F 213 ? O VAL F 213 
AC9 6 7 N VAL F 214 ? N VAL F 214 O ALA F 235 ? O ALA F 235 
AC9 7 8 N ILE F 240 ? N ILE F 240 O ASN F 278 ? O ASN F 278 
AC9 8 9 O ILE F 279 ? O ILE F 279 N PHE F 19  ? N PHE F 19  
AD1 1 2 N THR F 318 ? N THR F 318 O VAL F 362 ? O VAL F 362 
AD1 2 3 N ARG F 359 ? N ARG F 359 O VAL F 393 ? O VAL F 393 
AD1 3 4 O THR F 392 ? O THR F 392 N THR F 383 ? N THR F 383 
AD2 1 2 N PHE F 326 ? N PHE F 326 O CYS F 337 ? O CYS F 337 
AD2 2 3 N ILE F 338 ? N ILE F 338 O ARG F 407 ? O ARG F 407 
AD2 3 4 O ASP F 412 ? O ASP F 412 N ARG F 370 ? N ARG F 370 
AD3 1 2 N VAL F 344 ? N VAL F 344 O TYR F 398 ? O TYR F 398 
# 
_pdbx_entry_details.entry_id                   9HZ1 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OG1 
_pdbx_validate_close_contact.auth_asym_id_1   A 
_pdbx_validate_close_contact.auth_comp_id_1   THR 
_pdbx_validate_close_contact.auth_seq_id_1    34 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   NH1 
_pdbx_validate_close_contact.auth_asym_id_2   A 
_pdbx_validate_close_contact.auth_comp_id_2   ARG 
_pdbx_validate_close_contact.auth_seq_id_2    40 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.16 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CG B MET 28  ? ? SD B MET 28  ? ? CE  B MET 28  ? ? 86.79  100.20 -13.41 1.60 N 
2 1 CG B MET 295 ? ? SD B MET 295 ? ? CE  B MET 295 ? ? 89.79  100.20 -10.41 1.60 N 
3 1 NE C ARG 300 ? ? CZ C ARG 300 ? ? NH2 C ARG 300 ? ? 116.33 120.30 -3.97  0.50 N 
4 1 NE F ARG 115 ? ? CZ F ARG 115 ? ? NH1 F ARG 115 ? ? 117.12 120.30 -3.18  0.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LYS A 79  ? ? -161.65 118.85  
2  1 ASP A 138 ? ? -162.45 73.43   
3  1 ASN A 243 ? ? -115.24 -140.78 
4  1 ASP A 347 ? ? 55.63   -112.89 
5  1 ASP A 403 ? ? -170.27 109.24  
6  1 VAL A 405 ? ? 72.11   -60.92  
7  1 LYS B 79  ? ? -163.19 118.55  
8  1 ASP B 138 ? ? -161.71 71.91   
9  1 ASN B 243 ? ? -114.72 -140.80 
10 1 ASP B 347 ? ? 55.16   -112.45 
11 1 ASP B 403 ? ? -169.61 108.78  
12 1 VAL B 405 ? ? 72.52   -61.15  
13 1 LYS C 79  ? ? -161.99 119.46  
14 1 ASP C 138 ? ? -162.49 71.84   
15 1 ASN C 230 ? ? 78.25   -4.01   
16 1 ASN C 243 ? ? -115.95 -141.55 
17 1 ASP C 347 ? ? 55.02   -113.83 
18 1 ASP C 403 ? ? -170.32 108.14  
19 1 VAL C 405 ? ? 71.44   -60.86  
20 1 LYS D 79  ? ? -160.77 119.37  
21 1 ASP D 138 ? ? -164.59 72.40   
22 1 ASN D 230 ? ? 77.55   -1.59   
23 1 ASN D 243 ? ? -116.35 -140.88 
24 1 ASP D 347 ? ? 54.72   -116.34 
25 1 ASP D 403 ? ? -169.47 108.55  
26 1 VAL D 405 ? ? 72.05   -61.99  
27 1 LYS E 79  ? ? -161.68 119.33  
28 1 ASN E 230 ? ? 78.53   -3.91   
29 1 ASN E 243 ? ? -116.18 -141.10 
30 1 ASP E 347 ? ? 55.85   -112.34 
31 1 ASP E 403 ? ? -168.41 108.94  
32 1 VAL E 405 ? ? 71.74   -61.73  
33 1 LYS F 79  ? ? -160.78 119.73  
34 1 ASP F 138 ? ? -165.06 73.98   
35 1 ASP F 208 ? ? -170.87 138.26  
36 1 ASN F 243 ? ? -116.14 -141.02 
37 1 ASP F 347 ? ? 55.23   -112.34 
38 1 ASP F 403 ? ? -167.13 109.21  
39 1 VAL F 405 ? ? 72.10   -61.50  
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A ASN 202 ? A ASN 202 
2  1 Y 1 A ARG 203 ? A ARG 203 
3  1 Y 1 A GLY 204 ? A GLY 204 
4  1 Y 1 B LYS 201 ? B LYS 201 
5  1 Y 1 B ASN 202 ? B ASN 202 
6  1 Y 1 B ARG 203 ? B ARG 203 
7  1 Y 1 C MET 1   ? C MET 1   
8  1 Y 1 C GLY 199 ? C GLY 199 
9  1 Y 1 C LEU 200 ? C LEU 200 
10 1 Y 1 C LYS 201 ? C LYS 201 
11 1 Y 1 C ASN 202 ? C ASN 202 
12 1 Y 1 C ARG 203 ? C ARG 203 
13 1 Y 1 C GLY 204 ? C GLY 204 
14 1 Y 1 D MET 1   ? D MET 1   
15 1 Y 1 D GLY 199 ? D GLY 199 
16 1 Y 1 D LEU 200 ? D LEU 200 
17 1 Y 1 D LYS 201 ? D LYS 201 
18 1 Y 1 D ASN 202 ? D ASN 202 
19 1 Y 1 D ARG 203 ? D ARG 203 
20 1 Y 1 D GLY 204 ? D GLY 204 
21 1 Y 1 E MET 1   ? E MET 1   
22 1 Y 1 E GLY 199 ? E GLY 199 
23 1 Y 1 E LEU 200 ? E LEU 200 
24 1 Y 1 E LYS 201 ? E LYS 201 
25 1 Y 1 E ASN 202 ? E ASN 202 
26 1 Y 1 E ARG 203 ? E ARG 203 
27 1 Y 1 E GLY 204 ? E GLY 204 
28 1 Y 1 E GLN 205 ? E GLN 205 
29 1 Y 1 F MET 1   ? F MET 1   
30 1 Y 1 F GLY 199 ? F GLY 199 
31 1 Y 1 F LEU 200 ? F LEU 200 
32 1 Y 1 F LYS 201 ? F LYS 201 
33 1 Y 1 F ASN 202 ? F ASN 202 
34 1 Y 1 F ARG 203 ? F ARG 203 
35 1 Y 1 F GLY 204 ? F GLY 204 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N     N N N 1   
ALA CA    C N S 2   
ALA C     C N N 3   
ALA O     O N N 4   
ALA CB    C N N 5   
ALA OXT   O N N 6   
ALA H     H N N 7   
ALA H2    H N N 8   
ALA HA    H N N 9   
ALA HB1   H N N 10  
ALA HB2   H N N 11  
ALA HB3   H N N 12  
ALA HXT   H N N 13  
ARG N     N N N 14  
ARG CA    C N S 15  
ARG C     C N N 16  
ARG O     O N N 17  
ARG CB    C N N 18  
ARG CG    C N N 19  
ARG CD    C N N 20  
ARG NE    N N N 21  
ARG CZ    C N N 22  
ARG NH1   N N N 23  
ARG NH2   N N N 24  
ARG OXT   O N N 25  
ARG H     H N N 26  
ARG H2    H N N 27  
ARG HA    H N N 28  
ARG HB2   H N N 29  
ARG HB3   H N N 30  
ARG HG2   H N N 31  
ARG HG3   H N N 32  
ARG HD2   H N N 33  
ARG HD3   H N N 34  
ARG HE    H N N 35  
ARG HH11  H N N 36  
ARG HH12  H N N 37  
ARG HH21  H N N 38  
ARG HH22  H N N 39  
ARG HXT   H N N 40  
ASN N     N N N 41  
ASN CA    C N S 42  
ASN C     C N N 43  
ASN O     O N N 44  
ASN CB    C N N 45  
ASN CG    C N N 46  
ASN OD1   O N N 47  
ASN ND2   N N N 48  
ASN OXT   O N N 49  
ASN H     H N N 50  
ASN H2    H N N 51  
ASN HA    H N N 52  
ASN HB2   H N N 53  
ASN HB3   H N N 54  
ASN HD21  H N N 55  
ASN HD22  H N N 56  
ASN HXT   H N N 57  
ASP N     N N N 58  
ASP CA    C N S 59  
ASP C     C N N 60  
ASP O     O N N 61  
ASP CB    C N N 62  
ASP CG    C N N 63  
ASP OD1   O N N 64  
ASP OD2   O N N 65  
ASP OXT   O N N 66  
ASP H     H N N 67  
ASP H2    H N N 68  
ASP HA    H N N 69  
ASP HB2   H N N 70  
ASP HB3   H N N 71  
ASP HD2   H N N 72  
ASP HXT   H N N 73  
CYS N     N N N 74  
CYS CA    C N R 75  
CYS C     C N N 76  
CYS O     O N N 77  
CYS CB    C N N 78  
CYS SG    S N N 79  
CYS OXT   O N N 80  
CYS H     H N N 81  
CYS H2    H N N 82  
CYS HA    H N N 83  
CYS HB2   H N N 84  
CYS HB3   H N N 85  
CYS HG    H N N 86  
CYS HXT   H N N 87  
GLN N     N N N 88  
GLN CA    C N S 89  
GLN C     C N N 90  
GLN O     O N N 91  
GLN CB    C N N 92  
GLN CG    C N N 93  
GLN CD    C N N 94  
GLN OE1   O N N 95  
GLN NE2   N N N 96  
GLN OXT   O N N 97  
GLN H     H N N 98  
GLN H2    H N N 99  
GLN HA    H N N 100 
GLN HB2   H N N 101 
GLN HB3   H N N 102 
GLN HG2   H N N 103 
GLN HG3   H N N 104 
GLN HE21  H N N 105 
GLN HE22  H N N 106 
GLN HXT   H N N 107 
GLU N     N N N 108 
GLU CA    C N S 109 
GLU C     C N N 110 
GLU O     O N N 111 
GLU CB    C N N 112 
GLU CG    C N N 113 
GLU CD    C N N 114 
GLU OE1   O N N 115 
GLU OE2   O N N 116 
GLU OXT   O N N 117 
GLU H     H N N 118 
GLU H2    H N N 119 
GLU HA    H N N 120 
GLU HB2   H N N 121 
GLU HB3   H N N 122 
GLU HG2   H N N 123 
GLU HG3   H N N 124 
GLU HE2   H N N 125 
GLU HXT   H N N 126 
GLY N     N N N 127 
GLY CA    C N N 128 
GLY C     C N N 129 
GLY O     O N N 130 
GLY OXT   O N N 131 
GLY H     H N N 132 
GLY H2    H N N 133 
GLY HA2   H N N 134 
GLY HA3   H N N 135 
GLY HXT   H N N 136 
HIS N     N N N 137 
HIS CA    C N S 138 
HIS C     C N N 139 
HIS O     O N N 140 
HIS CB    C N N 141 
HIS CG    C Y N 142 
HIS ND1   N Y N 143 
HIS CD2   C Y N 144 
HIS CE1   C Y N 145 
HIS NE2   N Y N 146 
HIS OXT   O N N 147 
HIS H     H N N 148 
HIS H2    H N N 149 
HIS HA    H N N 150 
HIS HB2   H N N 151 
HIS HB3   H N N 152 
HIS HD1   H N N 153 
HIS HD2   H N N 154 
HIS HE1   H N N 155 
HIS HE2   H N N 156 
HIS HXT   H N N 157 
HOH O     O N N 158 
HOH H1    H N N 159 
HOH H2    H N N 160 
ILE N     N N N 161 
ILE CA    C N S 162 
ILE C     C N N 163 
ILE O     O N N 164 
ILE CB    C N S 165 
ILE CG1   C N N 166 
ILE CG2   C N N 167 
ILE CD1   C N N 168 
ILE OXT   O N N 169 
ILE H     H N N 170 
ILE H2    H N N 171 
ILE HA    H N N 172 
ILE HB    H N N 173 
ILE HG12  H N N 174 
ILE HG13  H N N 175 
ILE HG21  H N N 176 
ILE HG22  H N N 177 
ILE HG23  H N N 178 
ILE HD11  H N N 179 
ILE HD12  H N N 180 
ILE HD13  H N N 181 
ILE HXT   H N N 182 
JFZ C1    C N S 183 
JFZ C2    C N S 184 
JFZ O2    O N N 185 
JFZ C3    C N R 186 
JFZ O3    O N N 187 
JFZ C4    C N S 188 
JFZ O4    O N N 189 
JFZ C5    C N S 190 
JFZ C6    C N N 191 
JFZ O5    O N N 192 
JFZ O1    O N N 193 
JFZ "C1'" C Y N 194 
JFZ "C2'" C Y N 195 
JFZ "C3'" C Y N 196 
JFZ "C4'" C Y N 197 
JFZ "C5'" C Y N 198 
JFZ "C6'" C Y N 199 
JFZ "N1'" N N N 200 
JFZ "O2'" O N N 201 
JFZ "O3'" O N N 202 
JFZ H1    H N N 203 
JFZ H2    H N N 204 
JFZ HO2   H N N 205 
JFZ H4    H N N 206 
JFZ HO4   H N N 207 
JFZ H5    H N N 208 
JFZ H61   H N N 209 
JFZ H62   H N N 210 
JFZ H63   H N N 211 
JFZ H10   H N N 212 
JFZ H11   H N N 213 
JFZ H12   H N N 214 
JFZ H13   H N N 215 
JFZ H3    H N N 216 
JFZ HO3   H N N 217 
LEU N     N N N 218 
LEU CA    C N S 219 
LEU C     C N N 220 
LEU O     O N N 221 
LEU CB    C N N 222 
LEU CG    C N N 223 
LEU CD1   C N N 224 
LEU CD2   C N N 225 
LEU OXT   O N N 226 
LEU H     H N N 227 
LEU H2    H N N 228 
LEU HA    H N N 229 
LEU HB2   H N N 230 
LEU HB3   H N N 231 
LEU HG    H N N 232 
LEU HD11  H N N 233 
LEU HD12  H N N 234 
LEU HD13  H N N 235 
LEU HD21  H N N 236 
LEU HD22  H N N 237 
LEU HD23  H N N 238 
LEU HXT   H N N 239 
LYS N     N N N 240 
LYS CA    C N S 241 
LYS C     C N N 242 
LYS O     O N N 243 
LYS CB    C N N 244 
LYS CG    C N N 245 
LYS CD    C N N 246 
LYS CE    C N N 247 
LYS NZ    N N N 248 
LYS OXT   O N N 249 
LYS H     H N N 250 
LYS H2    H N N 251 
LYS HA    H N N 252 
LYS HB2   H N N 253 
LYS HB3   H N N 254 
LYS HG2   H N N 255 
LYS HG3   H N N 256 
LYS HD2   H N N 257 
LYS HD3   H N N 258 
LYS HE2   H N N 259 
LYS HE3   H N N 260 
LYS HZ1   H N N 261 
LYS HZ2   H N N 262 
LYS HZ3   H N N 263 
LYS HXT   H N N 264 
MET N     N N N 265 
MET CA    C N S 266 
MET C     C N N 267 
MET O     O N N 268 
MET CB    C N N 269 
MET CG    C N N 270 
MET SD    S N N 271 
MET CE    C N N 272 
MET OXT   O N N 273 
MET H     H N N 274 
MET H2    H N N 275 
MET HA    H N N 276 
MET HB2   H N N 277 
MET HB3   H N N 278 
MET HG2   H N N 279 
MET HG3   H N N 280 
MET HE1   H N N 281 
MET HE2   H N N 282 
MET HE3   H N N 283 
MET HXT   H N N 284 
PHE N     N N N 285 
PHE CA    C N S 286 
PHE C     C N N 287 
PHE O     O N N 288 
PHE CB    C N N 289 
PHE CG    C Y N 290 
PHE CD1   C Y N 291 
PHE CD2   C Y N 292 
PHE CE1   C Y N 293 
PHE CE2   C Y N 294 
PHE CZ    C Y N 295 
PHE OXT   O N N 296 
PHE H     H N N 297 
PHE H2    H N N 298 
PHE HA    H N N 299 
PHE HB2   H N N 300 
PHE HB3   H N N 301 
PHE HD1   H N N 302 
PHE HD2   H N N 303 
PHE HE1   H N N 304 
PHE HE2   H N N 305 
PHE HZ    H N N 306 
PHE HXT   H N N 307 
PRO N     N N N 308 
PRO CA    C N S 309 
PRO C     C N N 310 
PRO O     O N N 311 
PRO CB    C N N 312 
PRO CG    C N N 313 
PRO CD    C N N 314 
PRO OXT   O N N 315 
PRO H     H N N 316 
PRO HA    H N N 317 
PRO HB2   H N N 318 
PRO HB3   H N N 319 
PRO HG2   H N N 320 
PRO HG3   H N N 321 
PRO HD2   H N N 322 
PRO HD3   H N N 323 
PRO HXT   H N N 324 
SER N     N N N 325 
SER CA    C N S 326 
SER C     C N N 327 
SER O     O N N 328 
SER CB    C N N 329 
SER OG    O N N 330 
SER OXT   O N N 331 
SER H     H N N 332 
SER H2    H N N 333 
SER HA    H N N 334 
SER HB2   H N N 335 
SER HB3   H N N 336 
SER HG    H N N 337 
SER HXT   H N N 338 
THR N     N N N 339 
THR CA    C N S 340 
THR C     C N N 341 
THR O     O N N 342 
THR CB    C N R 343 
THR OG1   O N N 344 
THR CG2   C N N 345 
THR OXT   O N N 346 
THR H     H N N 347 
THR H2    H N N 348 
THR HA    H N N 349 
THR HB    H N N 350 
THR HG1   H N N 351 
THR HG21  H N N 352 
THR HG22  H N N 353 
THR HG23  H N N 354 
THR HXT   H N N 355 
TRP N     N N N 356 
TRP CA    C N S 357 
TRP C     C N N 358 
TRP O     O N N 359 
TRP CB    C N N 360 
TRP CG    C Y N 361 
TRP CD1   C Y N 362 
TRP CD2   C Y N 363 
TRP NE1   N Y N 364 
TRP CE2   C Y N 365 
TRP CE3   C Y N 366 
TRP CZ2   C Y N 367 
TRP CZ3   C Y N 368 
TRP CH2   C Y N 369 
TRP OXT   O N N 370 
TRP H     H N N 371 
TRP H2    H N N 372 
TRP HA    H N N 373 
TRP HB2   H N N 374 
TRP HB3   H N N 375 
TRP HD1   H N N 376 
TRP HE1   H N N 377 
TRP HE3   H N N 378 
TRP HZ2   H N N 379 
TRP HZ3   H N N 380 
TRP HH2   H N N 381 
TRP HXT   H N N 382 
TYR N     N N N 383 
TYR CA    C N S 384 
TYR C     C N N 385 
TYR O     O N N 386 
TYR CB    C N N 387 
TYR CG    C Y N 388 
TYR CD1   C Y N 389 
TYR CD2   C Y N 390 
TYR CE1   C Y N 391 
TYR CE2   C Y N 392 
TYR CZ    C Y N 393 
TYR OH    O N N 394 
TYR OXT   O N N 395 
TYR H     H N N 396 
TYR H2    H N N 397 
TYR HA    H N N 398 
TYR HB2   H N N 399 
TYR HB3   H N N 400 
TYR HD1   H N N 401 
TYR HD2   H N N 402 
TYR HE1   H N N 403 
TYR HE2   H N N 404 
TYR HH    H N N 405 
TYR HXT   H N N 406 
VAL N     N N N 407 
VAL CA    C N S 408 
VAL C     C N N 409 
VAL O     O N N 410 
VAL CB    C N N 411 
VAL CG1   C N N 412 
VAL CG2   C N N 413 
VAL OXT   O N N 414 
VAL H     H N N 415 
VAL H2    H N N 416 
VAL HA    H N N 417 
VAL HB    H N N 418 
VAL HG11  H N N 419 
VAL HG12  H N N 420 
VAL HG13  H N N 421 
VAL HG21  H N N 422 
VAL HG22  H N N 423 
VAL HG23  H N N 424 
VAL HXT   H N N 425 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA    sing N N 1   
ALA N     H     sing N N 2   
ALA N     H2    sing N N 3   
ALA CA    C     sing N N 4   
ALA CA    CB    sing N N 5   
ALA CA    HA    sing N N 6   
ALA C     O     doub N N 7   
ALA C     OXT   sing N N 8   
ALA CB    HB1   sing N N 9   
ALA CB    HB2   sing N N 10  
ALA CB    HB3   sing N N 11  
ALA OXT   HXT   sing N N 12  
ARG N     CA    sing N N 13  
ARG N     H     sing N N 14  
ARG N     H2    sing N N 15  
ARG CA    C     sing N N 16  
ARG CA    CB    sing N N 17  
ARG CA    HA    sing N N 18  
ARG C     O     doub N N 19  
ARG C     OXT   sing N N 20  
ARG CB    CG    sing N N 21  
ARG CB    HB2   sing N N 22  
ARG CB    HB3   sing N N 23  
ARG CG    CD    sing N N 24  
ARG CG    HG2   sing N N 25  
ARG CG    HG3   sing N N 26  
ARG CD    NE    sing N N 27  
ARG CD    HD2   sing N N 28  
ARG CD    HD3   sing N N 29  
ARG NE    CZ    sing N N 30  
ARG NE    HE    sing N N 31  
ARG CZ    NH1   sing N N 32  
ARG CZ    NH2   doub N N 33  
ARG NH1   HH11  sing N N 34  
ARG NH1   HH12  sing N N 35  
ARG NH2   HH21  sing N N 36  
ARG NH2   HH22  sing N N 37  
ARG OXT   HXT   sing N N 38  
ASN N     CA    sing N N 39  
ASN N     H     sing N N 40  
ASN N     H2    sing N N 41  
ASN CA    C     sing N N 42  
ASN CA    CB    sing N N 43  
ASN CA    HA    sing N N 44  
ASN C     O     doub N N 45  
ASN C     OXT   sing N N 46  
ASN CB    CG    sing N N 47  
ASN CB    HB2   sing N N 48  
ASN CB    HB3   sing N N 49  
ASN CG    OD1   doub N N 50  
ASN CG    ND2   sing N N 51  
ASN ND2   HD21  sing N N 52  
ASN ND2   HD22  sing N N 53  
ASN OXT   HXT   sing N N 54  
ASP N     CA    sing N N 55  
ASP N     H     sing N N 56  
ASP N     H2    sing N N 57  
ASP CA    C     sing N N 58  
ASP CA    CB    sing N N 59  
ASP CA    HA    sing N N 60  
ASP C     O     doub N N 61  
ASP C     OXT   sing N N 62  
ASP CB    CG    sing N N 63  
ASP CB    HB2   sing N N 64  
ASP CB    HB3   sing N N 65  
ASP CG    OD1   doub N N 66  
ASP CG    OD2   sing N N 67  
ASP OD2   HD2   sing N N 68  
ASP OXT   HXT   sing N N 69  
CYS N     CA    sing N N 70  
CYS N     H     sing N N 71  
CYS N     H2    sing N N 72  
CYS CA    C     sing N N 73  
CYS CA    CB    sing N N 74  
CYS CA    HA    sing N N 75  
CYS C     O     doub N N 76  
CYS C     OXT   sing N N 77  
CYS CB    SG    sing N N 78  
CYS CB    HB2   sing N N 79  
CYS CB    HB3   sing N N 80  
CYS SG    HG    sing N N 81  
CYS OXT   HXT   sing N N 82  
GLN N     CA    sing N N 83  
GLN N     H     sing N N 84  
GLN N     H2    sing N N 85  
GLN CA    C     sing N N 86  
GLN CA    CB    sing N N 87  
GLN CA    HA    sing N N 88  
GLN C     O     doub N N 89  
GLN C     OXT   sing N N 90  
GLN CB    CG    sing N N 91  
GLN CB    HB2   sing N N 92  
GLN CB    HB3   sing N N 93  
GLN CG    CD    sing N N 94  
GLN CG    HG2   sing N N 95  
GLN CG    HG3   sing N N 96  
GLN CD    OE1   doub N N 97  
GLN CD    NE2   sing N N 98  
GLN NE2   HE21  sing N N 99  
GLN NE2   HE22  sing N N 100 
GLN OXT   HXT   sing N N 101 
GLU N     CA    sing N N 102 
GLU N     H     sing N N 103 
GLU N     H2    sing N N 104 
GLU CA    C     sing N N 105 
GLU CA    CB    sing N N 106 
GLU CA    HA    sing N N 107 
GLU C     O     doub N N 108 
GLU C     OXT   sing N N 109 
GLU CB    CG    sing N N 110 
GLU CB    HB2   sing N N 111 
GLU CB    HB3   sing N N 112 
GLU CG    CD    sing N N 113 
GLU CG    HG2   sing N N 114 
GLU CG    HG3   sing N N 115 
GLU CD    OE1   doub N N 116 
GLU CD    OE2   sing N N 117 
GLU OE2   HE2   sing N N 118 
GLU OXT   HXT   sing N N 119 
GLY N     CA    sing N N 120 
GLY N     H     sing N N 121 
GLY N     H2    sing N N 122 
GLY CA    C     sing N N 123 
GLY CA    HA2   sing N N 124 
GLY CA    HA3   sing N N 125 
GLY C     O     doub N N 126 
GLY C     OXT   sing N N 127 
GLY OXT   HXT   sing N N 128 
HIS N     CA    sing N N 129 
HIS N     H     sing N N 130 
HIS N     H2    sing N N 131 
HIS CA    C     sing N N 132 
HIS CA    CB    sing N N 133 
HIS CA    HA    sing N N 134 
HIS C     O     doub N N 135 
HIS C     OXT   sing N N 136 
HIS CB    CG    sing N N 137 
HIS CB    HB2   sing N N 138 
HIS CB    HB3   sing N N 139 
HIS CG    ND1   sing Y N 140 
HIS CG    CD2   doub Y N 141 
HIS ND1   CE1   doub Y N 142 
HIS ND1   HD1   sing N N 143 
HIS CD2   NE2   sing Y N 144 
HIS CD2   HD2   sing N N 145 
HIS CE1   NE2   sing Y N 146 
HIS CE1   HE1   sing N N 147 
HIS NE2   HE2   sing N N 148 
HIS OXT   HXT   sing N N 149 
HOH O     H1    sing N N 150 
HOH O     H2    sing N N 151 
ILE N     CA    sing N N 152 
ILE N     H     sing N N 153 
ILE N     H2    sing N N 154 
ILE CA    C     sing N N 155 
ILE CA    CB    sing N N 156 
ILE CA    HA    sing N N 157 
ILE C     O     doub N N 158 
ILE C     OXT   sing N N 159 
ILE CB    CG1   sing N N 160 
ILE CB    CG2   sing N N 161 
ILE CB    HB    sing N N 162 
ILE CG1   CD1   sing N N 163 
ILE CG1   HG12  sing N N 164 
ILE CG1   HG13  sing N N 165 
ILE CG2   HG21  sing N N 166 
ILE CG2   HG22  sing N N 167 
ILE CG2   HG23  sing N N 168 
ILE CD1   HD11  sing N N 169 
ILE CD1   HD12  sing N N 170 
ILE CD1   HD13  sing N N 171 
ILE OXT   HXT   sing N N 172 
JFZ "O3'" "N1'" sing N N 173 
JFZ "O2'" "N1'" doub N N 174 
JFZ "N1'" "C4'" sing N N 175 
JFZ "C3'" "C4'" doub Y N 176 
JFZ "C3'" "C2'" sing Y N 177 
JFZ "C4'" "C5'" sing Y N 178 
JFZ "C2'" "C1'" doub Y N 179 
JFZ "C5'" "C6'" doub Y N 180 
JFZ "C1'" "C6'" sing Y N 181 
JFZ "C1'" O1    sing N N 182 
JFZ O1    C1    sing N N 183 
JFZ C5    C6    sing N N 184 
JFZ C5    O5    sing N N 185 
JFZ C5    C4    sing N N 186 
JFZ C1    O5    sing N N 187 
JFZ C1    C2    sing N N 188 
JFZ C4    C3    sing N N 189 
JFZ C4    O4    sing N N 190 
JFZ O2    C2    sing N N 191 
JFZ C2    C3    sing N N 192 
JFZ C3    O3    sing N N 193 
JFZ C1    H1    sing N N 194 
JFZ C2    H2    sing N N 195 
JFZ O2    HO2   sing N N 196 
JFZ C4    H4    sing N N 197 
JFZ O4    HO4   sing N N 198 
JFZ C5    H5    sing N N 199 
JFZ C6    H61   sing N N 200 
JFZ C6    H62   sing N N 201 
JFZ C6    H63   sing N N 202 
JFZ "C2'" H10   sing N N 203 
JFZ "C3'" H11   sing N N 204 
JFZ "C5'" H12   sing N N 205 
JFZ "C6'" H13   sing N N 206 
JFZ C3    H3    sing N N 207 
JFZ O3    HO3   sing N N 208 
LEU N     CA    sing N N 209 
LEU N     H     sing N N 210 
LEU N     H2    sing N N 211 
LEU CA    C     sing N N 212 
LEU CA    CB    sing N N 213 
LEU CA    HA    sing N N 214 
LEU C     O     doub N N 215 
LEU C     OXT   sing N N 216 
LEU CB    CG    sing N N 217 
LEU CB    HB2   sing N N 218 
LEU CB    HB3   sing N N 219 
LEU CG    CD1   sing N N 220 
LEU CG    CD2   sing N N 221 
LEU CG    HG    sing N N 222 
LEU CD1   HD11  sing N N 223 
LEU CD1   HD12  sing N N 224 
LEU CD1   HD13  sing N N 225 
LEU CD2   HD21  sing N N 226 
LEU CD2   HD22  sing N N 227 
LEU CD2   HD23  sing N N 228 
LEU OXT   HXT   sing N N 229 
LYS N     CA    sing N N 230 
LYS N     H     sing N N 231 
LYS N     H2    sing N N 232 
LYS CA    C     sing N N 233 
LYS CA    CB    sing N N 234 
LYS CA    HA    sing N N 235 
LYS C     O     doub N N 236 
LYS C     OXT   sing N N 237 
LYS CB    CG    sing N N 238 
LYS CB    HB2   sing N N 239 
LYS CB    HB3   sing N N 240 
LYS CG    CD    sing N N 241 
LYS CG    HG2   sing N N 242 
LYS CG    HG3   sing N N 243 
LYS CD    CE    sing N N 244 
LYS CD    HD2   sing N N 245 
LYS CD    HD3   sing N N 246 
LYS CE    NZ    sing N N 247 
LYS CE    HE2   sing N N 248 
LYS CE    HE3   sing N N 249 
LYS NZ    HZ1   sing N N 250 
LYS NZ    HZ2   sing N N 251 
LYS NZ    HZ3   sing N N 252 
LYS OXT   HXT   sing N N 253 
MET N     CA    sing N N 254 
MET N     H     sing N N 255 
MET N     H2    sing N N 256 
MET CA    C     sing N N 257 
MET CA    CB    sing N N 258 
MET CA    HA    sing N N 259 
MET C     O     doub N N 260 
MET C     OXT   sing N N 261 
MET CB    CG    sing N N 262 
MET CB    HB2   sing N N 263 
MET CB    HB3   sing N N 264 
MET CG    SD    sing N N 265 
MET CG    HG2   sing N N 266 
MET CG    HG3   sing N N 267 
MET SD    CE    sing N N 268 
MET CE    HE1   sing N N 269 
MET CE    HE2   sing N N 270 
MET CE    HE3   sing N N 271 
MET OXT   HXT   sing N N 272 
PHE N     CA    sing N N 273 
PHE N     H     sing N N 274 
PHE N     H2    sing N N 275 
PHE CA    C     sing N N 276 
PHE CA    CB    sing N N 277 
PHE CA    HA    sing N N 278 
PHE C     O     doub N N 279 
PHE C     OXT   sing N N 280 
PHE CB    CG    sing N N 281 
PHE CB    HB2   sing N N 282 
PHE CB    HB3   sing N N 283 
PHE CG    CD1   doub Y N 284 
PHE CG    CD2   sing Y N 285 
PHE CD1   CE1   sing Y N 286 
PHE CD1   HD1   sing N N 287 
PHE CD2   CE2   doub Y N 288 
PHE CD2   HD2   sing N N 289 
PHE CE1   CZ    doub Y N 290 
PHE CE1   HE1   sing N N 291 
PHE CE2   CZ    sing Y N 292 
PHE CE2   HE2   sing N N 293 
PHE CZ    HZ    sing N N 294 
PHE OXT   HXT   sing N N 295 
PRO N     CA    sing N N 296 
PRO N     CD    sing N N 297 
PRO N     H     sing N N 298 
PRO CA    C     sing N N 299 
PRO CA    CB    sing N N 300 
PRO CA    HA    sing N N 301 
PRO C     O     doub N N 302 
PRO C     OXT   sing N N 303 
PRO CB    CG    sing N N 304 
PRO CB    HB2   sing N N 305 
PRO CB    HB3   sing N N 306 
PRO CG    CD    sing N N 307 
PRO CG    HG2   sing N N 308 
PRO CG    HG3   sing N N 309 
PRO CD    HD2   sing N N 310 
PRO CD    HD3   sing N N 311 
PRO OXT   HXT   sing N N 312 
SER N     CA    sing N N 313 
SER N     H     sing N N 314 
SER N     H2    sing N N 315 
SER CA    C     sing N N 316 
SER CA    CB    sing N N 317 
SER CA    HA    sing N N 318 
SER C     O     doub N N 319 
SER C     OXT   sing N N 320 
SER CB    OG    sing N N 321 
SER CB    HB2   sing N N 322 
SER CB    HB3   sing N N 323 
SER OG    HG    sing N N 324 
SER OXT   HXT   sing N N 325 
THR N     CA    sing N N 326 
THR N     H     sing N N 327 
THR N     H2    sing N N 328 
THR CA    C     sing N N 329 
THR CA    CB    sing N N 330 
THR CA    HA    sing N N 331 
THR C     O     doub N N 332 
THR C     OXT   sing N N 333 
THR CB    OG1   sing N N 334 
THR CB    CG2   sing N N 335 
THR CB    HB    sing N N 336 
THR OG1   HG1   sing N N 337 
THR CG2   HG21  sing N N 338 
THR CG2   HG22  sing N N 339 
THR CG2   HG23  sing N N 340 
THR OXT   HXT   sing N N 341 
TRP N     CA    sing N N 342 
TRP N     H     sing N N 343 
TRP N     H2    sing N N 344 
TRP CA    C     sing N N 345 
TRP CA    CB    sing N N 346 
TRP CA    HA    sing N N 347 
TRP C     O     doub N N 348 
TRP C     OXT   sing N N 349 
TRP CB    CG    sing N N 350 
TRP CB    HB2   sing N N 351 
TRP CB    HB3   sing N N 352 
TRP CG    CD1   doub Y N 353 
TRP CG    CD2   sing Y N 354 
TRP CD1   NE1   sing Y N 355 
TRP CD1   HD1   sing N N 356 
TRP CD2   CE2   doub Y N 357 
TRP CD2   CE3   sing Y N 358 
TRP NE1   CE2   sing Y N 359 
TRP NE1   HE1   sing N N 360 
TRP CE2   CZ2   sing Y N 361 
TRP CE3   CZ3   doub Y N 362 
TRP CE3   HE3   sing N N 363 
TRP CZ2   CH2   doub Y N 364 
TRP CZ2   HZ2   sing N N 365 
TRP CZ3   CH2   sing Y N 366 
TRP CZ3   HZ3   sing N N 367 
TRP CH2   HH2   sing N N 368 
TRP OXT   HXT   sing N N 369 
TYR N     CA    sing N N 370 
TYR N     H     sing N N 371 
TYR N     H2    sing N N 372 
TYR CA    C     sing N N 373 
TYR CA    CB    sing N N 374 
TYR CA    HA    sing N N 375 
TYR C     O     doub N N 376 
TYR C     OXT   sing N N 377 
TYR CB    CG    sing N N 378 
TYR CB    HB2   sing N N 379 
TYR CB    HB3   sing N N 380 
TYR CG    CD1   doub Y N 381 
TYR CG    CD2   sing Y N 382 
TYR CD1   CE1   sing Y N 383 
TYR CD1   HD1   sing N N 384 
TYR CD2   CE2   doub Y N 385 
TYR CD2   HD2   sing N N 386 
TYR CE1   CZ    doub Y N 387 
TYR CE1   HE1   sing N N 388 
TYR CE2   CZ    sing Y N 389 
TYR CE2   HE2   sing N N 390 
TYR CZ    OH    sing N N 391 
TYR OH    HH    sing N N 392 
TYR OXT   HXT   sing N N 393 
VAL N     CA    sing N N 394 
VAL N     H     sing N N 395 
VAL N     H2    sing N N 396 
VAL CA    C     sing N N 397 
VAL CA    CB    sing N N 398 
VAL CA    HA    sing N N 399 
VAL C     O     doub N N 400 
VAL C     OXT   sing N N 401 
VAL CB    CG1   sing N N 402 
VAL CB    CG2   sing N N 403 
VAL CB    HB    sing N N 404 
VAL CG1   HG11  sing N N 405 
VAL CG1   HG12  sing N N 406 
VAL CG1   HG13  sing N N 407 
VAL CG2   HG21  sing N N 408 
VAL CG2   HG22  sing N N 409 
VAL CG2   HG23  sing N N 410 
VAL OXT   HXT   sing N N 411 
# 
_pdbx_audit_support.funding_organization   'Ministerio de Ciencia e Innovacion (MCIN)' 
_pdbx_audit_support.country                Spain 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8OZU 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9HZ1 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.005958 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.003226 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005706 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N     . MET A 1 1   ? -67.571  -65.668  1.664   1.00 58.87  ? 1    MET A N     1 
ATOM   2     C CA    . MET A 1 1   ? -69.011  -65.344  1.887   1.00 78.92  ? 1    MET A CA    1 
ATOM   3     C C     . MET A 1 1   ? -69.327  -63.887  1.505   1.00 75.47  ? 1    MET A C     1 
ATOM   4     O O     . MET A 1 1   ? -69.997  -63.664  0.494   1.00 66.82  ? 1    MET A O     1 
ATOM   5     C CB    . MET A 1 1   ? -69.508  -65.737  3.292   1.00 88.69  ? 1    MET A CB    1 
ATOM   6     C CG    . MET A 1 1   ? -71.036  -65.680  3.487   1.00 101.08 ? 1    MET A CG    1 
ATOM   7     S SD    . MET A 1 1   ? -72.118  -66.591  2.355   1.00 116.88 ? 1    MET A SD    1 
ATOM   8     C CE    . MET A 1 1   ? -73.833  -66.307  2.837   1.00 95.98  ? 1    MET A CE    1 
ATOM   9     N N     . THR A 1 2   ? -68.901  -62.881  2.300   1.00 61.01  ? 2    THR A N     1 
ATOM   10    C CA    . THR A 1 2   ? -69.321  -61.533  1.932   1.00 50.74  ? 2    THR A CA    1 
ATOM   11    C C     . THR A 1 2   ? -68.426  -61.002  0.811   1.00 51.01  ? 2    THR A C     1 
ATOM   12    O O     . THR A 1 2   ? -67.283  -61.409  0.673   1.00 49.87  ? 2    THR A O     1 
ATOM   13    C CB    . THR A 1 2   ? -69.395  -60.527  3.077   1.00 52.80  ? 2    THR A CB    1 
ATOM   14    O OG1   . THR A 1 2   ? -68.058  -60.476  3.565   1.00 50.18  ? 2    THR A OG1   1 
ATOM   15    C CG2   . THR A 1 2   ? -70.322  -60.925  4.214   1.00 51.18  ? 2    THR A CG2   1 
ATOM   16    N N     . GLU A 1 3   ? -68.980  -60.079  0.044   1.00 44.73  ? 3    GLU A N     1 
ATOM   17    C CA    . GLU A 1 3   ? -68.308  -59.455  -1.068  1.00 43.36  ? 3    GLU A CA    1 
ATOM   18    C C     . GLU A 1 3   ? -67.889  -58.048  -0.682  1.00 37.44  ? 3    GLU A C     1 
ATOM   19    O O     . GLU A 1 3   ? -68.454  -57.452  0.229   1.00 32.11  ? 3    GLU A O     1 
ATOM   20    C CB    . GLU A 1 3   ? -69.172  -59.513  -2.318  1.00 45.55  ? 3    GLU A CB    1 
ATOM   21    C CG    . GLU A 1 3   ? -68.806  -60.820  -3.007  1.00 69.77  ? 3    GLU A CG    1 
ATOM   22    C CD    . GLU A 1 3   ? -69.373  -61.106  -4.377  1.00 91.10  ? 3    GLU A CD    1 
ATOM   23    O OE1   . GLU A 1 3   ? -70.185  -60.313  -4.902  1.00 90.75  ? 3    GLU A OE1   1 
ATOM   24    O OE2   . GLU A 1 3   ? -68.944  -62.149  -4.896  1.00 95.75  ? 3    GLU A OE2   1 
ATOM   25    N N     . PRO A 1 4   ? -66.828  -57.500  -1.305  1.00 32.96  ? 4    PRO A N     1 
ATOM   26    C CA    . PRO A 1 4   ? -66.352  -56.177  -0.913  1.00 26.32  ? 4    PRO A CA    1 
ATOM   27    C C     . PRO A 1 4   ? -67.384  -55.083  -1.144  1.00 26.03  ? 4    PRO A C     1 
ATOM   28    O O     . PRO A 1 4   ? -68.058  -55.085  -2.167  1.00 26.24  ? 4    PRO A O     1 
ATOM   29    C CB    . PRO A 1 4   ? -65.123  -55.992  -1.787  1.00 26.09  ? 4    PRO A CB    1 
ATOM   30    C CG    . PRO A 1 4   ? -65.134  -57.075  -2.829  1.00 24.15  ? 4    PRO A CG    1 
ATOM   31    C CD    . PRO A 1 4   ? -65.950  -58.188  -2.274  1.00 27.24  ? 4    PRO A CD    1 
ATOM   32    N N     . LEU A 1 5   ? -67.501  -54.144  -0.193  1.00 23.30  ? 5    LEU A N     1 
ATOM   33    C CA    . LEU A 1 5   ? -68.221  -52.901  -0.429  1.00 24.34  ? 5    LEU A CA    1 
ATOM   34    C C     . LEU A 1 5   ? -67.713  -52.228  -1.700  1.00 28.59  ? 5    LEU A C     1 
ATOM   35    O O     . LEU A 1 5   ? -66.556  -52.362  -2.030  1.00 29.67  ? 5    LEU A O     1 
ATOM   36    C CB    . LEU A 1 5   ? -68.044  -52.012  0.808   1.00 24.38  ? 5    LEU A CB    1 
ATOM   37    C CG    . LEU A 1 5   ? -68.817  -52.488  2.046   1.00 26.37  ? 5    LEU A CG    1 
ATOM   38    C CD1   . LEU A 1 5   ? -68.508  -51.681  3.279   1.00 25.42  ? 5    LEU A CD1   1 
ATOM   39    C CD2   . LEU A 1 5   ? -70.317  -52.396  1.739   1.00 26.29  ? 5    LEU A CD2   1 
ATOM   40    N N     . PRO A 1 6   ? -68.534  -51.452  -2.435  1.00 29.26  ? 6    PRO A N     1 
ATOM   41    C CA    . PRO A 1 6   ? -68.044  -50.713  -3.603  1.00 27.20  ? 6    PRO A CA    1 
ATOM   42    C C     . PRO A 1 6   ? -66.694  -50.003  -3.430  1.00 27.37  ? 6    PRO A C     1 
ATOM   43    O O     . PRO A 1 6   ? -65.871  -50.044  -4.348  1.00 25.30  ? 6    PRO A O     1 
ATOM   44    C CB    . PRO A 1 6   ? -69.229  -49.792  -4.013  1.00 25.37  ? 6    PRO A CB    1 
ATOM   45    C CG    . PRO A 1 6   ? -70.432  -50.585  -3.485  1.00 26.33  ? 6    PRO A CG    1 
ATOM   46    C CD    . PRO A 1 6   ? -69.980  -51.248  -2.196  1.00 28.61  ? 6    PRO A CD    1 
ATOM   47    N N     . ARG A 1 7   ? -66.455  -49.323  -2.299  1.00 22.78  ? 7    ARG A N     1 
ATOM   48    C CA    . ARG A 1 7   ? -65.245  -48.509  -2.218  1.00 21.56  ? 7    ARG A CA    1 
ATOM   49    C C     . ARG A 1 7   ? -64.022  -49.437  -2.116  1.00 25.92  ? 7    ARG A C     1 
ATOM   50    O O     . ARG A 1 7   ? -62.927  -49.092  -2.563  1.00 25.35  ? 7    ARG A O     1 
ATOM   51    C CB    . ARG A 1 7   ? -65.230  -47.469  -1.088  1.00 21.21  ? 7    ARG A CB    1 
ATOM   52    C CG    . ARG A 1 7   ? -65.197  -48.025  0.328   1.00 20.82  ? 7    ARG A CG    1 
ATOM   53    C CD    . ARG A 1 7   ? -64.921  -46.965  1.424   1.00 21.76  ? 7    ARG A CD    1 
ATOM   54    N NE    . ARG A 1 7   ? -64.965  -47.636  2.741   1.00 23.10  ? 7    ARG A NE    1 
ATOM   55    C CZ    . ARG A 1 7   ? -66.095  -48.010  3.354   1.00 24.06  ? 7    ARG A CZ    1 
ATOM   56    N NH1   . ARG A 1 7   ? -67.248  -47.602  2.845   1.00 22.27  ? 7    ARG A NH1   1 
ATOM   57    N NH2   . ARG A 1 7   ? -66.077  -48.736  4.467   1.00 23.41  ? 7    ARG A NH2   1 
ATOM   58    N N     . ILE A 1 8   ? -64.227  -50.637  -1.549  1.00 23.23  ? 8    ILE A N     1 
ATOM   59    C CA    . ILE A 1 8   ? -63.166  -51.616  -1.393  1.00 24.31  ? 8    ILE A CA    1 
ATOM   60    C C     . ILE A 1 8   ? -62.895  -52.338  -2.724  1.00 28.10  ? 8    ILE A C     1 
ATOM   61    O O     . ILE A 1 8   ? -61.742  -52.578  -3.059  1.00 24.21  ? 8    ILE A O     1 
ATOM   62    C CB    . ILE A 1 8   ? -63.452  -52.553  -0.206  1.00 22.39  ? 8    ILE A CB    1 
ATOM   63    C CG1   . ILE A 1 8   ? -63.453  -51.751  1.105   1.00 22.24  ? 8    ILE A CG1   1 
ATOM   64    C CG2   . ILE A 1 8   ? -62.426  -53.704  -0.165  1.00 22.12  ? 8    ILE A CG2   1 
ATOM   65    C CD1   . ILE A 1 8   ? -63.740  -52.561  2.352   1.00 25.54  ? 8    ILE A CD1   1 
ATOM   66    N N     . GLN A 1 9   ? -63.953  -52.637  -3.502  1.00 28.30  ? 9    GLN A N     1 
ATOM   67    C CA    . GLN A 1 9   ? -63.820  -53.123  -4.869  1.00 31.72  ? 9    GLN A CA    1 
ATOM   68    C C     . GLN A 1 9   ? -62.987  -52.119  -5.660  1.00 28.55  ? 9    GLN A C     1 
ATOM   69    O O     . GLN A 1 9   ? -62.127  -52.518  -6.417  1.00 28.75  ? 9    GLN A O     1 
ATOM   70    C CB    . GLN A 1 9   ? -65.189  -53.258  -5.555  1.00 34.86  ? 9    GLN A CB    1 
ATOM   71    C CG    . GLN A 1 9   ? -65.400  -54.393  -6.553  1.00 55.55  ? 9    GLN A CG    1 
ATOM   72    C CD    . GLN A 1 9   ? -65.185  -53.930  -7.980  1.00 77.67  ? 9    GLN A CD    1 
ATOM   73    O OE1   . GLN A 1 9   ? -65.857  -53.010  -8.455  1.00 90.26  ? 9    GLN A OE1   1 
ATOM   74    N NE2   . GLN A 1 9   ? -64.232  -54.534  -8.678  1.00 79.42  ? 9    GLN A NE2   1 
ATOM   75    N N     . HIS A 1 10  ? -63.273  -50.824  -5.512  1.00 23.80  ? 10   HIS A N     1 
ATOM   76    C CA    . HIS A 1 10  ? -62.547  -49.808  -6.253  1.00 25.99  ? 10   HIS A CA    1 
ATOM   77    C C     . HIS A 1 10  ? -61.075  -49.818  -5.818  1.00 25.28  ? 10   HIS A C     1 
ATOM   78    O O     . HIS A 1 10  ? -60.185  -49.678  -6.656  1.00 24.78  ? 10   HIS A O     1 
ATOM   79    C CB    . HIS A 1 10  ? -63.275  -48.457  -6.226  1.00 26.71  ? 10   HIS A CB    1 
ATOM   80    C CG    . HIS A 1 10  ? -62.578  -47.382  -7.014  1.00 47.54  ? 10   HIS A CG    1 
ATOM   81    N ND1   . HIS A 1 10  ? -62.279  -47.521  -8.360  1.00 57.44  ? 10   HIS A ND1   1 
ATOM   82    C CD2   . HIS A 1 10  ? -62.062  -46.184  -6.655  1.00 49.79  ? 10   HIS A CD2   1 
ATOM   83    C CE1   . HIS A 1 10  ? -61.646  -46.441  -8.800  1.00 49.11  ? 10   HIS A CE1   1 
ATOM   84    N NE2   . HIS A 1 10  ? -61.512  -45.607  -7.786  1.00 48.43  ? 10   HIS A NE2   1 
ATOM   85    N N     . TYR A 1 11  ? -60.836  -50.034  -4.520  1.00 22.14  ? 11   TYR A N     1 
ATOM   86    C CA    . TYR A 1 11  ? -59.496  -50.082  -3.963  1.00 22.00  ? 11   TYR A CA    1 
ATOM   87    C C     . TYR A 1 11  ? -58.695  -51.219  -4.605  1.00 21.81  ? 11   TYR A C     1 
ATOM   88    O O     . TYR A 1 11  ? -57.563  -51.025  -5.027  1.00 22.62  ? 11   TYR A O     1 
ATOM   89    C CB    . TYR A 1 11  ? -59.556  -50.183  -2.434  1.00 19.81  ? 11   TYR A CB    1 
ATOM   90    C CG    . TYR A 1 11  ? -58.179  -50.462  -1.846  1.00 23.07  ? 11   TYR A CG    1 
ATOM   91    C CD1   . TYR A 1 11  ? -57.274  -49.425  -1.624  1.00 21.26  ? 11   TYR A CD1   1 
ATOM   92    C CD2   . TYR A 1 11  ? -57.766  -51.766  -1.563  1.00 20.48  ? 11   TYR A CD2   1 
ATOM   93    C CE1   . TYR A 1 11  ? -56.008  -49.669  -1.121  1.00 20.91  ? 11   TYR A CE1   1 
ATOM   94    C CE2   . TYR A 1 11  ? -56.497  -52.027  -1.076  1.00 20.63  ? 11   TYR A CE2   1 
ATOM   95    C CZ    . TYR A 1 11  ? -55.622  -50.977  -0.849  1.00 23.91  ? 11   TYR A CZ    1 
ATOM   96    O OH    . TYR A 1 11  ? -54.373  -51.253  -0.361  1.00 23.97  ? 11   TYR A OH    1 
ATOM   97    N N     . GLU A 1 12  ? -59.284  -52.411  -4.681  1.00 23.30  ? 12   GLU A N     1 
ATOM   98    C CA    . GLU A 1 12  ? -58.596  -53.577  -5.223  1.00 23.74  ? 12   GLU A CA    1 
ATOM   99    C C     . GLU A 1 12  ? -58.278  -53.378  -6.704  1.00 21.84  ? 12   GLU A C     1 
ATOM   100   O O     . GLU A 1 12  ? -57.335  -53.981  -7.213  1.00 20.73  ? 12   GLU A O     1 
ATOM   101   C CB    . GLU A 1 12  ? -59.379  -54.867  -4.973  1.00 24.21  ? 12   GLU A CB    1 
ATOM   102   C CG    . GLU A 1 12  ? -59.573  -55.149  -3.483  1.00 27.14  ? 12   GLU A CG    1 
ATOM   103   C CD    . GLU A 1 12  ? -60.134  -56.556  -3.214  1.00 34.62  ? 12   GLU A CD    1 
ATOM   104   O OE1   . GLU A 1 12  ? -61.091  -56.982  -3.915  1.00 35.02  ? 12   GLU A OE1   1 
ATOM   105   O OE2   . GLU A 1 12  ? -59.630  -57.238  -2.292  1.00 31.98  ? 12   GLU A OE2   1 
ATOM   106   N N     . ASP A 1 13  ? -59.053  -52.517  -7.391  1.00 21.65  ? 13   ASP A N     1 
ATOM   107   C CA    . ASP A 1 13  ? -58.796  -52.245  -8.793  1.00 23.99  ? 13   ASP A CA    1 
ATOM   108   C C     . ASP A 1 13  ? -57.627  -51.283  -8.971  1.00 24.83  ? 13   ASP A C     1 
ATOM   109   O O     . ASP A 1 13  ? -57.156  -51.108  -10.089 1.00 24.28  ? 13   ASP A O     1 
ATOM   110   C CB    . ASP A 1 13  ? -60.001  -51.637  -9.483  1.00 24.93  ? 13   ASP A CB    1 
ATOM   111   C CG    . ASP A 1 13  ? -61.064  -52.623  -9.954  1.00 30.55  ? 13   ASP A CG    1 
ATOM   112   O OD1   . ASP A 1 13  ? -60.809  -53.856  -9.922  1.00 29.43  ? 13   ASP A OD1   1 
ATOM   113   O OD2   . ASP A 1 13  ? -62.155  -52.136  -10.335 1.00 32.14  ? 13   ASP A OD2   1 
ATOM   114   N N     . LEU A 1 14  ? -57.210  -50.617  -7.891  1.00 23.86  ? 14   LEU A N     1 
ATOM   115   C CA    . LEU A 1 14  ? -56.109  -49.676  -7.992  1.00 25.15  ? 14   LEU A CA    1 
ATOM   116   C C     . LEU A 1 14  ? -54.822  -50.438  -8.307  1.00 21.84  ? 14   LEU A C     1 
ATOM   117   O O     . LEU A 1 14  ? -54.009  -49.993  -9.115  1.00 22.36  ? 14   LEU A O     1 
ATOM   118   C CB    . LEU A 1 14  ? -55.984  -48.861  -6.709  1.00 22.01  ? 14   LEU A CB    1 
ATOM   119   C CG    . LEU A 1 14  ? -57.203  -48.010  -6.334  1.00 23.25  ? 14   LEU A CG    1 
ATOM   120   C CD1   . LEU A 1 14  ? -56.917  -47.440  -4.932  1.00 23.67  ? 14   LEU A CD1   1 
ATOM   121   C CD2   . LEU A 1 14  ? -57.508  -46.915  -7.334  1.00 17.58  ? 14   LEU A CD2   1 
ATOM   122   N N     . GLY A 1 15  ? -54.636  -51.578  -7.642  1.00 22.60  ? 15   GLY A N     1 
ATOM   123   C CA    . GLY A 1 15  ? -53.524  -52.478  -7.933  1.00 23.12  ? 15   GLY A CA    1 
ATOM   124   C C     . GLY A 1 15  ? -52.199  -51.991  -7.336  1.00 21.59  ? 15   GLY A C     1 
ATOM   125   O O     . GLY A 1 15  ? -51.644  -52.632  -6.439  1.00 22.60  ? 15   GLY A O     1 
ATOM   126   N N     . LEU A 1 16  ? -51.722  -50.850  -7.850  1.00 19.25  ? 16   LEU A N     1 
ATOM   127   C CA    . LEU A 1 16  ? -50.388  -50.365  -7.561  1.00 19.11  ? 16   LEU A CA    1 
ATOM   128   C C     . LEU A 1 16  ? -50.490  -48.921  -7.079  1.00 21.66  ? 16   LEU A C     1 
ATOM   129   O O     . LEU A 1 16  ? -51.152  -48.077  -7.719  1.00 21.65  ? 16   LEU A O     1 
ATOM   130   C CB    . LEU A 1 16  ? -49.525  -50.459  -8.822  1.00 20.23  ? 16   LEU A CB    1 
ATOM   131   C CG    . LEU A 1 16  ? -48.201  -49.679  -8.813  1.00 19.51  ? 16   LEU A CG    1 
ATOM   132   C CD1   . LEU A 1 16  ? -47.194  -50.263  -7.798  1.00 16.42  ? 16   LEU A CD1   1 
ATOM   133   C CD2   . LEU A 1 16  ? -47.602  -49.589  -10.221 1.00 18.87  ? 16   LEU A CD2   1 
ATOM   134   N N     . GLY A 1 17  ? -49.829  -48.653  -5.934  1.00 16.63  ? 17   GLY A N     1 
ATOM   135   C CA    . GLY A 1 17  ? -49.698  -47.278  -5.508  1.00 17.52  ? 17   GLY A CA    1 
ATOM   136   C C     . GLY A 1 17  ? -48.237  -46.903  -5.278  1.00 20.43  ? 17   GLY A C     1 
ATOM   137   O O     . GLY A 1 17  ? -47.386  -47.763  -5.062  1.00 21.33  ? 17   GLY A O     1 
ATOM   138   N N     . LEU A 1 18  ? -47.981  -45.600  -5.249  1.00 19.51  ? 18   LEU A N     1 
ATOM   139   C CA    . LEU A 1 18  ? -46.688  -45.092  -4.845  1.00 20.13  ? 18   LEU A CA    1 
ATOM   140   C C     . LEU A 1 18  ? -46.766  -44.601  -3.405  1.00 21.86  ? 18   LEU A C     1 
ATOM   141   O O     . LEU A 1 18  ? -47.680  -43.842  -3.050  1.00 22.02  ? 18   LEU A O     1 
ATOM   142   C CB    . LEU A 1 18  ? -46.470  -43.947  -5.831  1.00 22.49  ? 18   LEU A CB    1 
ATOM   143   C CG    . LEU A 1 18  ? -45.064  -43.368  -5.844  1.00 26.66  ? 18   LEU A CG    1 
ATOM   144   C CD1   . LEU A 1 18  ? -44.178  -44.482  -6.357  1.00 28.26  ? 18   LEU A CD1   1 
ATOM   145   C CD2   . LEU A 1 18  ? -45.052  -42.173  -6.809  1.00 29.58  ? 18   LEU A CD2   1 
ATOM   146   N N     . PHE A 1 19  ? -45.832  -45.079  -2.562  1.00 22.55  ? 19   PHE A N     1 
ATOM   147   C CA    . PHE A 1 19  ? -45.674  -44.603  -1.200  1.00 19.01  ? 19   PHE A CA    1 
ATOM   148   C C     . PHE A 1 19  ? -44.572  -43.538  -1.201  1.00 21.96  ? 19   PHE A C     1 
ATOM   149   O O     . PHE A 1 19  ? -43.508  -43.761  -1.789  1.00 22.51  ? 19   PHE A O     1 
ATOM   150   C CB    . PHE A 1 19  ? -45.205  -45.794  -0.376  1.00 19.65  ? 19   PHE A CB    1 
ATOM   151   C CG    . PHE A 1 19  ? -45.652  -45.833  1.093   1.00 20.74  ? 19   PHE A CG    1 
ATOM   152   C CD1   . PHE A 1 19  ? -45.970  -44.670  1.794   1.00 20.10  ? 19   PHE A CD1   1 
ATOM   153   C CD2   . PHE A 1 19  ? -45.679  -47.057  1.785   1.00 20.20  ? 19   PHE A CD2   1 
ATOM   154   C CE1   . PHE A 1 19  ? -46.357  -44.729  3.133   1.00 20.24  ? 19   PHE A CE1   1 
ATOM   155   C CE2   . PHE A 1 19  ? -46.057  -47.123  3.118   1.00 20.37  ? 19   PHE A CE2   1 
ATOM   156   C CZ    . PHE A 1 19  ? -46.401  -45.952  3.799   1.00 22.25  ? 19   PHE A CZ    1 
ATOM   157   N N     . ILE A 1 20  ? -44.815  -42.391  -0.536  1.00 20.99  ? 20   ILE A N     1 
ATOM   158   C CA    . ILE A 1 20  ? -43.822  -41.317  -0.492  1.00 20.22  ? 20   ILE A CA    1 
ATOM   159   C C     . ILE A 1 20  ? -43.527  -40.884  0.945   1.00 20.21  ? 20   ILE A C     1 
ATOM   160   O O     . ILE A 1 20  ? -44.423  -40.451  1.661   1.00 19.69  ? 20   ILE A O     1 
ATOM   161   C CB    . ILE A 1 20  ? -44.270  -40.125  -1.342  1.00 19.03  ? 20   ILE A CB    1 
ATOM   162   C CG1   . ILE A 1 20  ? -44.470  -40.564  -2.799  1.00 17.29  ? 20   ILE A CG1   1 
ATOM   163   C CG2   . ILE A 1 20  ? -43.266  -38.963  -1.209  1.00 17.28  ? 20   ILE A CG2   1 
ATOM   164   C CD1   . ILE A 1 20  ? -44.948  -39.438  -3.684  1.00 18.79  ? 20   ILE A CD1   1 
ATOM   165   N N     . HIS A 1 21  ? -42.257  -41.033  1.353   1.00 18.62  ? 21   HIS A N     1 
ATOM   166   C CA    . HIS A 1 21  ? -41.785  -40.621  2.658   1.00 17.97  ? 21   HIS A CA    1 
ATOM   167   C C     . HIS A 1 21  ? -41.000  -39.327  2.494   1.00 19.94  ? 21   HIS A C     1 
ATOM   168   O O     . HIS A 1 21  ? -39.974  -39.273  1.794   1.00 18.69  ? 21   HIS A O     1 
ATOM   169   C CB    . HIS A 1 21  ? -40.878  -41.684  3.285   1.00 16.90  ? 21   HIS A CB    1 
ATOM   170   C CG    . HIS A 1 21  ? -41.659  -42.778  3.931   1.00 18.37  ? 21   HIS A CG    1 
ATOM   171   N ND1   . HIS A 1 21  ? -42.360  -43.727  3.209   1.00 17.32  ? 21   HIS A ND1   1 
ATOM   172   C CD2   . HIS A 1 21  ? -41.882  -43.060  5.233   1.00 17.73  ? 21   HIS A CD2   1 
ATOM   173   C CE1   . HIS A 1 21  ? -42.969  -44.560  4.065   1.00 17.72  ? 21   HIS A CE1   1 
ATOM   174   N NE2   . HIS A 1 21  ? -42.707  -44.155  5.289   1.00 17.14  ? 21   HIS A NE2   1 
ATOM   175   N N     . TRP A 1 22  ? -41.498  -38.281  3.164   1.00 19.66  ? 22   TRP A N     1 
ATOM   176   C CA    . TRP A 1 22  ? -40.821  -37.005  3.152   1.00 20.72  ? 22   TRP A CA    1 
ATOM   177   C C     . TRP A 1 22  ? -41.155  -36.282  4.450   1.00 25.81  ? 22   TRP A C     1 
ATOM   178   O O     . TRP A 1 22  ? -42.336  -36.146  4.780   1.00 20.53  ? 22   TRP A O     1 
ATOM   179   C CB    . TRP A 1 22  ? -41.325  -36.204  1.953   1.00 19.05  ? 22   TRP A CB    1 
ATOM   180   C CG    . TRP A 1 22  ? -40.653  -34.870  1.794   1.00 21.28  ? 22   TRP A CG    1 
ATOM   181   C CD1   . TRP A 1 22  ? -39.347  -34.533  2.043   1.00 19.08  ? 22   TRP A CD1   1 
ATOM   182   C CD2   . TRP A 1 22  ? -41.309  -33.673  1.319   1.00 20.25  ? 22   TRP A CD2   1 
ATOM   183   N NE1   . TRP A 1 22  ? -39.139  -33.208  1.727   1.00 21.14  ? 22   TRP A NE1   1 
ATOM   184   C CE2   . TRP A 1 22  ? -40.323  -32.656  1.290   1.00 20.74  ? 22   TRP A CE2   1 
ATOM   185   C CE3   . TRP A 1 22  ? -42.612  -33.382  0.898   1.00 18.83  ? 22   TRP A CE3   1 
ATOM   186   C CZ2   . TRP A 1 22  ? -40.624  -31.355  0.884   1.00 20.71  ? 22   TRP A CZ2   1 
ATOM   187   C CZ3   . TRP A 1 22  ? -42.906  -32.106  0.481   1.00 19.72  ? 22   TRP A CZ3   1 
ATOM   188   C CH2   . TRP A 1 22  ? -41.923  -31.107  0.488   1.00 20.94  ? 22   TRP A CH2   1 
ATOM   189   N N     . GLY A 1 23  ? -40.108  -35.834  5.164   1.00 23.96  ? 23   GLY A N     1 
ATOM   190   C CA    . GLY A 1 23  ? -40.295  -35.097  6.402   1.00 25.01  ? 23   GLY A CA    1 
ATOM   191   C C     . GLY A 1 23  ? -39.013  -34.343  6.740   1.00 27.90  ? 23   GLY A C     1 
ATOM   192   O O     . GLY A 1 23  ? -38.137  -34.198  5.879   1.00 24.43  ? 23   GLY A O     1 
ATOM   193   N N     . LEU A 1 24  ? -38.885  -33.891  7.996   1.00 23.07  ? 24   LEU A N     1 
ATOM   194   C CA    . LEU A 1 24  ? -37.685  -33.168  8.369   1.00 23.27  ? 24   LEU A CA    1 
ATOM   195   C C     . LEU A 1 24  ? -36.493  -34.126  8.263   1.00 24.48  ? 24   LEU A C     1 
ATOM   196   O O     . LEU A 1 24  ? -35.396  -33.683  7.890   1.00 22.91  ? 24   LEU A O     1 
ATOM   197   C CB    . LEU A 1 24  ? -37.783  -32.552  9.772   1.00 23.10  ? 24   LEU A CB    1 
ATOM   198   C CG    . LEU A 1 24  ? -38.921  -31.548  9.980   1.00 22.19  ? 24   LEU A CG    1 
ATOM   199   C CD1   . LEU A 1 24  ? -38.976  -31.041  11.421  1.00 19.75  ? 24   LEU A CD1   1 
ATOM   200   C CD2   . LEU A 1 24  ? -38.901  -30.380  8.947   1.00 19.62  ? 24   LEU A CD2   1 
ATOM   201   N N     . TYR A 1 25  ? -36.720  -35.425  8.560   1.00 21.58  ? 25   TYR A N     1 
ATOM   202   C CA    . TYR A 1 25  ? -35.676  -36.438  8.522   1.00 20.48  ? 25   TYR A CA    1 
ATOM   203   C C     . TYR A 1 25  ? -34.971  -36.429  7.176   1.00 21.11  ? 25   TYR A C     1 
ATOM   204   O O     . TYR A 1 25  ? -33.790  -36.743  7.102   1.00 24.00  ? 25   TYR A O     1 
ATOM   205   C CB    . TYR A 1 25  ? -36.183  -37.859  8.783   1.00 19.82  ? 25   TYR A CB    1 
ATOM   206   C CG    . TYR A 1 25  ? -37.493  -38.175  8.080   1.00 21.44  ? 25   TYR A CG    1 
ATOM   207   C CD1   . TYR A 1 25  ? -37.520  -38.623  6.752   1.00 20.19  ? 25   TYR A CD1   1 
ATOM   208   C CD2   . TYR A 1 25  ? -38.712  -38.045  8.748   1.00 19.86  ? 25   TYR A CD2   1 
ATOM   209   C CE1   . TYR A 1 25  ? -38.732  -38.907  6.119   1.00 20.99  ? 25   TYR A CE1   1 
ATOM   210   C CE2   . TYR A 1 25  ? -39.921  -38.319  8.126   1.00 20.62  ? 25   TYR A CE2   1 
ATOM   211   C CZ    . TYR A 1 25  ? -39.934  -38.760  6.803   1.00 24.08  ? 25   TYR A CZ    1 
ATOM   212   O OH    . TYR A 1 25  ? -41.132  -38.998  6.181   1.00 24.01  ? 25   TYR A OH    1 
ATOM   213   N N     . SER A 1 26  ? -35.694  -36.079  6.110   1.00 21.03  ? 26   SER A N     1 
ATOM   214   C CA    . SER A 1 26  ? -35.155  -36.168  4.759   1.00 23.38  ? 26   SER A CA    1 
ATOM   215   C C     . SER A 1 26  ? -33.903  -35.302  4.615   1.00 24.05  ? 26   SER A C     1 
ATOM   216   O O     . SER A 1 26  ? -33.007  -35.610  3.814   1.00 23.50  ? 26   SER A O     1 
ATOM   217   C CB    . SER A 1 26  ? -36.198  -35.805  3.731   1.00 21.64  ? 26   SER A CB    1 
ATOM   218   O OG    . SER A 1 26  ? -37.353  -36.627  3.892   1.00 19.70  ? 26   SER A OG    1 
ATOM   219   N N     . GLN A 1 27  ? -33.828  -34.217  5.389   1.00 23.51  ? 27   GLN A N     1 
ATOM   220   C CA    . GLN A 1 27  ? -32.665  -33.342  5.275   1.00 24.12  ? 27   GLN A CA    1 
ATOM   221   C C     . GLN A 1 27  ? -31.385  -34.049  5.720   1.00 23.75  ? 27   GLN A C     1 
ATOM   222   O O     . GLN A 1 27  ? -30.326  -33.664  5.295   1.00 24.54  ? 27   GLN A O     1 
ATOM   223   C CB    . GLN A 1 27  ? -32.797  -32.027  6.038   1.00 25.63  ? 27   GLN A CB    1 
ATOM   224   C CG    . GLN A 1 27  ? -33.734  -31.054  5.319   1.00 27.36  ? 27   GLN A CG    1 
ATOM   225   C CD    . GLN A 1 27  ? -34.128  -29.905  6.214   1.00 28.92  ? 27   GLN A CD    1 
ATOM   226   O OE1   . GLN A 1 27  ? -35.276  -29.829  6.673   1.00 30.30  ? 27   GLN A OE1   1 
ATOM   227   N NE2   . GLN A 1 27  ? -33.159  -29.050  6.516   1.00 28.51  ? 27   GLN A NE2   1 
ATOM   228   N N     . MET A 1 28  ? -31.465  -35.083  6.553   1.00 23.60  ? 28   MET A N     1 
ATOM   229   C CA    . MET A 1 28  ? -30.253  -35.705  7.054   1.00 25.16  ? 28   MET A CA    1 
ATOM   230   C C     . MET A 1 28  ? -29.883  -36.944  6.246   1.00 23.86  ? 28   MET A C     1 
ATOM   231   O O     . MET A 1 28  ? -28.749  -37.400  6.368   1.00 24.23  ? 28   MET A O     1 
ATOM   232   C CB    . MET A 1 28  ? -30.501  -36.247  8.463   1.00 32.43  ? 28   MET A CB    1 
ATOM   233   C CG    . MET A 1 28  ? -31.267  -35.292  9.315   1.00 43.82  ? 28   MET A CG    1 
ATOM   234   S SD    . MET A 1 28  ? -30.081  -34.464  10.365  1.00 60.79  ? 28   MET A SD    1 
ATOM   235   C CE    . MET A 1 28  ? -29.154  -33.403  9.236   1.00 35.66  ? 28   MET A CE    1 
ATOM   236   N N     . ALA A 1 29  ? -30.862  -37.562  5.560   1.00 20.59  ? 29   ALA A N     1 
ATOM   237   C CA    . ALA A 1 29  ? -30.584  -38.657  4.626   1.00 20.87  ? 29   ALA A CA    1 
ATOM   238   C C     . ALA A 1 29  ? -29.944  -39.840  5.346   1.00 21.06  ? 29   ALA A C     1 
ATOM   239   O O     . ALA A 1 29  ? -29.068  -40.513  4.791   1.00 21.80  ? 29   ALA A O     1 
ATOM   240   C CB    . ALA A 1 29  ? -29.723  -38.179  3.442   1.00 16.90  ? 29   ALA A CB    1 
ATOM   241   N N     . VAL A 1 30  ? -30.407  -40.098  6.582   1.00 20.45  ? 30   VAL A N     1 
ATOM   242   C CA    . VAL A 1 30  ? -29.958  -41.276  7.310   1.00 19.87  ? 30   VAL A CA    1 
ATOM   243   C C     . VAL A 1 30  ? -31.182  -42.009  7.859   1.00 22.01  ? 30   VAL A C     1 
ATOM   244   O O     . VAL A 1 30  ? -31.115  -42.562  8.956   1.00 22.19  ? 30   VAL A O     1 
ATOM   245   C CB    . VAL A 1 30  ? -28.898  -40.971  8.407   1.00 21.59  ? 30   VAL A CB    1 
ATOM   246   C CG1   . VAL A 1 30  ? -27.526  -40.587  7.829   1.00 18.86  ? 30   VAL A CG1   1 
ATOM   247   C CG2   . VAL A 1 30  ? -29.365  -39.892  9.389   1.00 17.50  ? 30   VAL A CG2   1 
ATOM   248   N N     . GLY A 1 31  ? -32.299  -42.048  7.106   1.00 23.01  ? 31   GLY A N     1 
ATOM   249   C CA    . GLY A 1 31  ? -33.458  -42.840  7.537   1.00 23.33  ? 31   GLY A CA    1 
ATOM   250   C C     . GLY A 1 31  ? -34.484  -42.009  8.322   1.00 25.25  ? 31   GLY A C     1 
ATOM   251   O O     . GLY A 1 31  ? -34.133  -41.033  8.985   1.00 27.37  ? 31   GLY A O     1 
ATOM   252   N N     . GLU A 1 32  ? -35.755  -42.390  8.241   1.00 23.06  ? 32   GLU A N     1 
ATOM   253   C CA    . GLU A 1 32  ? -36.846  -41.610  8.813   1.00 24.07  ? 32   GLU A CA    1 
ATOM   254   C C     . GLU A 1 32  ? -36.899  -41.744  10.344  1.00 25.70  ? 32   GLU A C     1 
ATOM   255   O O     . GLU A 1 32  ? -37.482  -40.880  11.004  1.00 25.54  ? 32   GLU A O     1 
ATOM   256   C CB    . GLU A 1 32  ? -38.203  -41.916  8.154   1.00 21.08  ? 32   GLU A CB    1 
ATOM   257   C CG    . GLU A 1 32  ? -38.721  -43.320  8.440   1.00 17.60  ? 32   GLU A CG    1 
ATOM   258   C CD    . GLU A 1 32  ? -38.024  -44.537  7.798   1.00 22.04  ? 32   GLU A CD    1 
ATOM   259   O OE1   . GLU A 1 32  ? -37.064  -44.428  6.973   1.00 21.93  ? 32   GLU A OE1   1 
ATOM   260   O OE2   . GLU A 1 32  ? -38.428  -45.674  8.138   1.00 20.16  ? 32   GLU A OE2   1 
ATOM   261   N N     . TRP A 1 33  ? -36.320  -42.818  10.916  1.00 22.23  ? 33   TRP A N     1 
ATOM   262   C CA    . TRP A 1 33  ? -36.317  -42.981  12.360  1.00 22.31  ? 33   TRP A CA    1 
ATOM   263   C C     . TRP A 1 33  ? -35.119  -42.301  13.029  1.00 24.36  ? 33   TRP A C     1 
ATOM   264   O O     . TRP A 1 33  ? -34.844  -42.567  14.199  1.00 25.56  ? 33   TRP A O     1 
ATOM   265   C CB    . TRP A 1 33  ? -36.333  -44.460  12.739  1.00 21.20  ? 33   TRP A CB    1 
ATOM   266   C CG    . TRP A 1 33  ? -37.687  -45.117  12.701  1.00 24.22  ? 33   TRP A CG    1 
ATOM   267   C CD1   . TRP A 1 33  ? -38.455  -45.367  11.598  1.00 22.07  ? 33   TRP A CD1   1 
ATOM   268   C CD2   . TRP A 1 33  ? -38.393  -45.691  13.832  1.00 26.63  ? 33   TRP A CD2   1 
ATOM   269   N NE1   . TRP A 1 33  ? -39.618  -45.988  11.970  1.00 23.67  ? 33   TRP A NE1   1 
ATOM   270   C CE2   . TRP A 1 33  ? -39.604  -46.235  13.321  1.00 24.61  ? 33   TRP A CE2   1 
ATOM   271   C CE3   . TRP A 1 33  ? -38.122  -45.807  15.209  1.00 24.55  ? 33   TRP A CE3   1 
ATOM   272   C CZ2   . TRP A 1 33  ? -40.534  -46.881  14.141  1.00 24.94  ? 33   TRP A CZ2   1 
ATOM   273   C CZ3   . TRP A 1 33  ? -39.041  -46.445  16.020  1.00 24.34  ? 33   TRP A CZ3   1 
ATOM   274   C CH2   . TRP A 1 33  ? -40.239  -46.971  15.497  1.00 25.43  ? 33   TRP A CH2   1 
ATOM   275   N N     . THR A 1 34  ? -34.394  -41.433  12.312  1.00 21.61  ? 34   THR A N     1 
ATOM   276   C CA    . THR A 1 34  ? -33.108  -40.948  12.799  1.00 23.68  ? 34   THR A CA    1 
ATOM   277   C C     . THR A 1 34  ? -33.223  -40.292  14.189  1.00 26.74  ? 34   THR A C     1 
ATOM   278   O O     . THR A 1 34  ? -32.362  -40.508  15.043  1.00 24.68  ? 34   THR A O     1 
ATOM   279   C CB    . THR A 1 34  ? -32.458  -40.041  11.747  1.00 23.55  ? 34   THR A CB    1 
ATOM   280   O OG1   . THR A 1 34  ? -31.225  -39.686  12.327  1.00 21.89  ? 34   THR A OG1   1 
ATOM   281   C CG2   . THR A 1 34  ? -33.201  -38.749  11.477  1.00 18.80  ? 34   THR A CG2   1 
ATOM   282   N N     . GLU A 1 35  ? -34.289  -39.510  14.433  1.00 26.13  ? 35   GLU A N     1 
ATOM   283   C CA    . GLU A 1 35  ? -34.404  -38.790  15.691  1.00 28.92  ? 35   GLU A CA    1 
ATOM   284   C C     . GLU A 1 35  ? -34.332  -39.741  16.887  1.00 27.21  ? 35   GLU A C     1 
ATOM   285   O O     . GLU A 1 35  ? -33.591  -39.487  17.831  1.00 26.02  ? 35   GLU A O     1 
ATOM   286   C CB    . GLU A 1 35  ? -35.613  -37.862  15.789  1.00 34.42  ? 35   GLU A CB    1 
ATOM   287   C CG    . GLU A 1 35  ? -35.668  -37.094  17.108  1.00 33.88  ? 35   GLU A CG    1 
ATOM   288   C CD    . GLU A 1 35  ? -36.892  -36.188  17.236  1.00 38.34  ? 35   GLU A CD    1 
ATOM   289   O OE1   . GLU A 1 35  ? -37.917  -36.407  16.554  1.00 33.35  ? 35   GLU A OE1   1 
ATOM   290   O OE2   . GLU A 1 35  ? -36.816  -35.198  18.000  1.00 41.58  ? 35   GLU A OE2   1 
ATOM   291   N N     . LEU A 1 36  ? -35.097  -40.832  16.844  1.00 26.56  ? 36   LEU A N     1 
ATOM   292   C CA    . LEU A 1 36  ? -35.102  -41.773  17.944  1.00 28.09  ? 36   LEU A CA    1 
ATOM   293   C C     . LEU A 1 36  ? -33.853  -42.653  17.906  1.00 34.82  ? 36   LEU A C     1 
ATOM   294   O O     . LEU A 1 36  ? -33.140  -42.756  18.900  1.00 38.55  ? 36   LEU A O     1 
ATOM   295   C CB    . LEU A 1 36  ? -36.376  -42.608  17.968  1.00 28.17  ? 36   LEU A CB    1 
ATOM   296   C CG    . LEU A 1 36  ? -36.518  -43.530  19.191  1.00 32.70  ? 36   LEU A CG    1 
ATOM   297   C CD1   . LEU A 1 36  ? -37.971  -43.745  19.438  1.00 28.94  ? 36   LEU A CD1   1 
ATOM   298   C CD2   . LEU A 1 36  ? -35.899  -44.899  19.038  1.00 32.15  ? 36   LEU A CD2   1 
ATOM   299   N N     . ILE A 1 37  ? -33.564  -43.282  16.757  1.00 30.52  ? 37   ILE A N     1 
ATOM   300   C CA    . ILE A 1 37  ? -32.559  -44.333  16.748  1.00 25.33  ? 37   ILE A CA    1 
ATOM   301   C C     . ILE A 1 37  ? -31.143  -43.772  16.928  1.00 25.36  ? 37   ILE A C     1 
ATOM   302   O O     . ILE A 1 37  ? -30.305  -44.420  17.537  1.00 24.06  ? 37   ILE A O     1 
ATOM   303   C CB    . ILE A 1 37  ? -32.703  -45.239  15.517  1.00 26.16  ? 37   ILE A CB    1 
ATOM   304   C CG1   . ILE A 1 37  ? -34.006  -46.026  15.599  1.00 26.03  ? 37   ILE A CG1   1 
ATOM   305   C CG2   . ILE A 1 37  ? -31.491  -46.175  15.375  1.00 24.80  ? 37   ILE A CG2   1 
ATOM   306   C CD1   . ILE A 1 37  ? -34.295  -46.817  14.330  1.00 29.87  ? 37   ILE A CD1   1 
ATOM   307   N N     . HIS A 1 38  ? -30.871  -42.566  16.427  1.00 24.44  ? 38   HIS A N     1 
ATOM   308   C CA    . HIS A 1 38  ? -29.561  -41.967  16.622  1.00 26.47  ? 38   HIS A CA    1 
ATOM   309   C C     . HIS A 1 38  ? -29.532  -41.109  17.892  1.00 31.49  ? 38   HIS A C     1 
ATOM   310   O O     . HIS A 1 38  ? -28.580  -40.341  18.055  1.00 26.86  ? 38   HIS A O     1 
ATOM   311   C CB    . HIS A 1 38  ? -29.169  -41.083  15.421  1.00 24.02  ? 38   HIS A CB    1 
ATOM   312   C CG    . HIS A 1 38  ? -28.884  -41.888  14.200  1.00 26.78  ? 38   HIS A CG    1 
ATOM   313   N ND1   . HIS A 1 38  ? -29.485  -41.628  12.988  1.00 27.80  ? 38   HIS A ND1   1 
ATOM   314   C CD2   . HIS A 1 38  ? -28.152  -43.016  14.004  1.00 25.81  ? 38   HIS A CD2   1 
ATOM   315   C CE1   . HIS A 1 38  ? -29.063  -42.527  12.096  1.00 27.23  ? 38   HIS A CE1   1 
ATOM   316   N NE2   . HIS A 1 38  ? -28.289  -43.389  12.701  1.00 25.07  ? 38   HIS A NE2   1 
ATOM   317   N N     . HIS A 1 39  ? -30.586  -41.193  18.745  1.00 33.82  ? 39   HIS A N     1 
ATOM   318   C CA    . HIS A 1 39  ? -30.619  -40.562  20.062  1.00 38.19  ? 39   HIS A CA    1 
ATOM   319   C C     . HIS A 1 39  ? -30.310  -39.067  19.923  1.00 32.80  ? 39   HIS A C     1 
ATOM   320   O O     . HIS A 1 39  ? -29.422  -38.537  20.566  1.00 30.81  ? 39   HIS A O     1 
ATOM   321   C CB    . HIS A 1 39  ? -29.765  -41.355  21.071  1.00 46.80  ? 39   HIS A CB    1 
ATOM   322   C CG    . HIS A 1 39  ? -29.846  -40.875  22.506  1.00 99.05  ? 39   HIS A CG    1 
ATOM   323   N ND1   . HIS A 1 39  ? -30.958  -41.035  23.319  1.00 112.15 ? 39   HIS A ND1   1 
ATOM   324   C CD2   . HIS A 1 39  ? -28.941  -40.210  23.273  1.00 106.13 ? 39   HIS A CD2   1 
ATOM   325   C CE1   . HIS A 1 39  ? -30.736  -40.486  24.512  1.00 93.59  ? 39   HIS A CE1   1 
ATOM   326   N NE2   . HIS A 1 39  ? -29.515  -39.987  24.510  1.00 99.08  ? 39   HIS A NE2   1 
ATOM   327   N N     . ARG A 1 40  ? -31.000  -38.373  19.026  1.00 34.07  ? 40   ARG A N     1 
ATOM   328   C CA    . ARG A 1 40  ? -30.654  -36.981  18.787  1.00 34.94  ? 40   ARG A CA    1 
ATOM   329   C C     . ARG A 1 40  ? -31.274  -36.097  19.873  1.00 35.88  ? 40   ARG A C     1 
ATOM   330   O O     . ARG A 1 40  ? -32.305  -36.444  20.447  1.00 31.99  ? 40   ARG A O     1 
ATOM   331   C CB    . ARG A 1 40  ? -31.189  -36.538  17.424  1.00 32.81  ? 40   ARG A CB    1 
ATOM   332   C CG    . ARG A 1 40  ? -30.406  -37.204  16.302  1.00 35.61  ? 40   ARG A CG    1 
ATOM   333   C CD    . ARG A 1 40  ? -30.793  -36.698  14.953  1.00 39.55  ? 40   ARG A CD    1 
ATOM   334   N NE    . ARG A 1 40  ? -29.480  -36.734  14.276  1.00 45.33  ? 40   ARG A NE    1 
ATOM   335   C CZ    . ARG A 1 40  ? -29.197  -37.246  13.126  1.00 44.96  ? 40   ARG A CZ    1 
ATOM   336   N NH1   . ARG A 1 40  ? -30.119  -37.835  12.418  1.00 64.75  ? 40   ARG A NH1   1 
ATOM   337   N NH2   . ARG A 1 40  ? -28.009  -37.127  12.594  1.00 62.98  ? 40   ARG A NH2   1 
ATOM   338   N N     . ASN A 1 41  ? -30.639  -34.953  20.140  1.00 34.19  ? 41   ASN A N     1 
ATOM   339   C CA    . ASN A 1 41  ? -31.257  -33.896  20.922  1.00 38.19  ? 41   ASN A CA    1 
ATOM   340   C C     . ASN A 1 41  ? -32.536  -33.395  20.223  1.00 34.73  ? 41   ASN A C     1 
ATOM   341   O O     . ASN A 1 41  ? -32.483  -32.839  19.125  1.00 28.14  ? 41   ASN A O     1 
ATOM   342   C CB    . ASN A 1 41  ? -30.249  -32.774  21.175  1.00 38.07  ? 41   ASN A CB    1 
ATOM   343   C CG    . ASN A 1 41  ? -30.876  -31.640  21.952  1.00 41.44  ? 41   ASN A CG    1 
ATOM   344   O OD1   . ASN A 1 41  ? -30.930  -31.677  23.185  1.00 42.03  ? 41   ASN A OD1   1 
ATOM   345   N ND2   . ASN A 1 41  ? -31.384  -30.635  21.250  1.00 33.63  ? 41   ASN A ND2   1 
ATOM   346   N N     . GLN A 1 42  ? -33.683  -33.511  20.894  1.00 28.88  ? 42   GLN A N     1 
ATOM   347   C CA    . GLN A 1 42  ? -34.949  -33.130  20.303  1.00 29.47  ? 42   GLN A CA    1 
ATOM   348   C C     . GLN A 1 42  ? -34.936  -31.681  19.816  1.00 33.07  ? 42   GLN A C     1 
ATOM   349   O O     . GLN A 1 42  ? -35.370  -31.383  18.689  1.00 34.88  ? 42   GLN A O     1 
ATOM   350   C CB    . GLN A 1 42  ? -36.131  -33.407  21.231  1.00 29.37  ? 42   GLN A CB    1 
ATOM   351   C CG    . GLN A 1 42  ? -37.453  -32.988  20.594  1.00 37.93  ? 42   GLN A CG    1 
ATOM   352   C CD    . GLN A 1 42  ? -38.647  -33.521  21.341  1.00 43.15  ? 42   GLN A CD    1 
ATOM   353   O OE1   . GLN A 1 42  ? -38.497  -34.101  22.425  1.00 46.19  ? 42   GLN A OE1   1 
ATOM   354   N NE2   . GLN A 1 42  ? -39.829  -33.333  20.768  1.00 43.75  ? 42   GLN A NE2   1 
ATOM   355   N N     . HIS A 1 43  ? -34.448  -30.769  20.664  1.00 36.71  ? 43   HIS A N     1 
ATOM   356   C CA    . HIS A 1 43  ? -34.489  -29.359  20.337  1.00 32.77  ? 43   HIS A CA    1 
ATOM   357   C C     . HIS A 1 43  ? -33.689  -29.111  19.050  1.00 31.08  ? 43   HIS A C     1 
ATOM   358   O O     . HIS A 1 43  ? -34.099  -28.335  18.194  1.00 34.55  ? 43   HIS A O     1 
ATOM   359   C CB    . HIS A 1 43  ? -34.061  -28.515  21.556  1.00 37.79  ? 43   HIS A CB    1 
ATOM   360   C CG    . HIS A 1 43  ? -33.891  -27.073  21.180  1.00 44.66  ? 43   HIS A CG    1 
ATOM   361   N ND1   . HIS A 1 43  ? -32.703  -26.519  20.706  1.00 47.02  ? 43   HIS A ND1   1 
ATOM   362   C CD2   . HIS A 1 43  ? -34.840  -26.079  21.129  1.00 40.10  ? 43   HIS A CD2   1 
ATOM   363   C CE1   . HIS A 1 43  ? -32.925  -25.241  20.354  1.00 46.51  ? 43   HIS A CE1   1 
ATOM   364   N NE2   . HIS A 1 43  ? -34.212  -24.963  20.601  1.00 46.45  ? 43   HIS A NE2   1 
ATOM   365   N N     . ASP A 1 44  ? -32.517  -29.735  18.944  1.00 28.36  ? 44   ASP A N     1 
ATOM   366   C CA    . ASP A 1 44  ? -31.627  -29.535  17.811  1.00 31.70  ? 44   ASP A CA    1 
ATOM   367   C C     . ASP A 1 44  ? -32.219  -30.128  16.545  1.00 33.84  ? 44   ASP A C     1 
ATOM   368   O O     . ASP A 1 44  ? -32.216  -29.473  15.520  1.00 28.12  ? 44   ASP A O     1 
ATOM   369   C CB    . ASP A 1 44  ? -30.215  -30.020  18.098  1.00 44.23  ? 44   ASP A CB    1 
ATOM   370   C CG    . ASP A 1 44  ? -29.497  -29.273  19.218  1.00 49.91  ? 44   ASP A CG    1 
ATOM   371   O OD1   . ASP A 1 44  ? -29.943  -28.144  19.539  1.00 50.80  ? 44   ASP A OD1   1 
ATOM   372   O OD2   . ASP A 1 44  ? -28.532  -29.840  19.781  1.00 47.55  ? 44   ASP A OD2   1 
ATOM   373   N N     . TYR A 1 45  ? -32.770  -31.345  16.636  1.00 33.69  ? 45   TYR A N     1 
ATOM   374   C CA    . TYR A 1 45  ? -33.410  -31.998  15.500  1.00 32.28  ? 45   TYR A CA    1 
ATOM   375   C C     . TYR A 1 45  ? -34.567  -31.142  14.974  1.00 31.71  ? 45   TYR A C     1 
ATOM   376   O O     . TYR A 1 45  ? -34.651  -30.908  13.765  1.00 28.41  ? 45   TYR A O     1 
ATOM   377   C CB    . TYR A 1 45  ? -33.832  -33.413  15.905  1.00 28.96  ? 45   TYR A CB    1 
ATOM   378   C CG    . TYR A 1 45  ? -34.548  -34.142  14.782  1.00 29.31  ? 45   TYR A CG    1 
ATOM   379   C CD1   . TYR A 1 45  ? -33.837  -34.816  13.779  1.00 27.94  ? 45   TYR A CD1   1 
ATOM   380   C CD2   . TYR A 1 45  ? -35.938  -34.139  14.703  1.00 28.58  ? 45   TYR A CD2   1 
ATOM   381   C CE1   . TYR A 1 45  ? -34.488  -35.481  12.746  1.00 23.64  ? 45   TYR A CE1   1 
ATOM   382   C CE2   . TYR A 1 45  ? -36.597  -34.824  13.693  1.00 27.05  ? 45   TYR A CE2   1 
ATOM   383   C CZ    . TYR A 1 45  ? -35.870  -35.495  12.716  1.00 25.91  ? 45   TYR A CZ    1 
ATOM   384   O OH    . TYR A 1 45  ? -36.557  -36.169  11.746  1.00 28.07  ? 45   TYR A OH    1 
ATOM   385   N N     . GLU A 1 46  ? -35.406  -30.609  15.888  1.00 31.29  ? 46   GLU A N     1 
ATOM   386   C CA    . GLU A 1 46  ? -36.583  -29.851  15.490  1.00 27.89  ? 46   GLU A CA    1 
ATOM   387   C C     . GLU A 1 46  ? -36.232  -28.518  14.825  1.00 29.85  ? 46   GLU A C     1 
ATOM   388   O O     . GLU A 1 46  ? -37.076  -27.920  14.152  1.00 31.27  ? 46   GLU A O     1 
ATOM   389   C CB    . GLU A 1 46  ? -37.609  -29.779  16.605  1.00 27.68  ? 46   GLU A CB    1 
ATOM   390   C CG    . GLU A 1 46  ? -38.107  -31.162  17.022  1.00 32.33  ? 46   GLU A CG    1 
ATOM   391   C CD    . GLU A 1 46  ? -39.284  -31.117  17.991  1.00 39.47  ? 46   GLU A CD    1 
ATOM   392   O OE1   . GLU A 1 46  ? -39.586  -29.976  18.403  1.00 48.40  ? 46   GLU A OE1   1 
ATOM   393   O OE2   . GLU A 1 46  ? -39.954  -32.133  18.266  1.00 36.43  ? 46   GLU A OE2   1 
ATOM   394   N N     . GLN A 1 47  ? -34.984  -28.064  14.956  1.00 28.22  ? 47   GLN A N     1 
ATOM   395   C CA    . GLN A 1 47  ? -34.524  -26.875  14.241  1.00 31.18  ? 47   GLN A CA    1 
ATOM   396   C C     . GLN A 1 47  ? -34.546  -27.075  12.718  1.00 34.77  ? 47   GLN A C     1 
ATOM   397   O O     . GLN A 1 47  ? -34.493  -26.086  11.968  1.00 31.40  ? 47   GLN A O     1 
ATOM   398   C CB    . GLN A 1 47  ? -33.097  -26.489  14.635  1.00 35.80  ? 47   GLN A CB    1 
ATOM   399   C CG    . GLN A 1 47  ? -32.946  -25.990  16.074  1.00 51.18  ? 47   GLN A CG    1 
ATOM   400   C CD    . GLN A 1 47  ? -33.714  -24.711  16.331  1.00 59.51  ? 47   GLN A CD    1 
ATOM   401   O OE1   . GLN A 1 47  ? -33.385  -23.633  15.809  1.00 59.80  ? 47   GLN A OE1   1 
ATOM   402   N NE2   . GLN A 1 47  ? -34.793  -24.836  17.089  1.00 62.20  ? 47   GLN A NE2   1 
ATOM   403   N N     . LEU A 1 48  ? -34.613  -28.343  12.262  1.00 30.04  ? 48   LEU A N     1 
ATOM   404   C CA    . LEU A 1 48  ? -34.688  -28.641  10.836  1.00 29.02  ? 48   LEU A CA    1 
ATOM   405   C C     . LEU A 1 48  ? -35.907  -27.968  10.201  1.00 28.93  ? 48   LEU A C     1 
ATOM   406   O O     . LEU A 1 48  ? -35.918  -27.767  8.979   1.00 27.34  ? 48   LEU A O     1 
ATOM   407   C CB    . LEU A 1 48  ? -34.682  -30.147  10.558  1.00 27.69  ? 48   LEU A CB    1 
ATOM   408   C CG    . LEU A 1 48  ? -33.355  -30.857  10.848  1.00 26.47  ? 48   LEU A CG    1 
ATOM   409   C CD1   . LEU A 1 48  ? -33.498  -32.371  10.791  1.00 20.63  ? 48   LEU A CD1   1 
ATOM   410   C CD2   . LEU A 1 48  ? -32.258  -30.319  9.922   1.00 23.26  ? 48   LEU A CD2   1 
ATOM   411   N N     . ILE A 1 49  ? -36.929  -27.609  11.015  1.00 25.70  ? 49   ILE A N     1 
ATOM   412   C CA    . ILE A 1 49  ? -38.057  -26.856  10.467  1.00 26.31  ? 49   ILE A CA    1 
ATOM   413   C C     . ILE A 1 49  ? -37.589  -25.568  9.772   1.00 29.38  ? 49   ILE A C     1 
ATOM   414   O O     . ILE A 1 49  ? -38.194  -25.124  8.790   1.00 30.45  ? 49   ILE A O     1 
ATOM   415   C CB    . ILE A 1 49  ? -39.158  -26.584  11.503  1.00 25.56  ? 49   ILE A CB    1 
ATOM   416   C CG1   . ILE A 1 49  ? -40.458  -26.105  10.800  1.00 27.88  ? 49   ILE A CG1   1 
ATOM   417   C CG2   . ILE A 1 49  ? -38.704  -25.595  12.595  1.00 20.36  ? 49   ILE A CG2   1 
ATOM   418   C CD1   . ILE A 1 49  ? -41.664  -26.083  11.730  1.00 28.31  ? 49   ILE A CD1   1 
ATOM   419   N N     . LYS A 1 50  ? -36.489  -24.970  10.267  1.00 30.75  ? 50   LYS A N     1 
ATOM   420   C CA    . LYS A 1 50  ? -36.085  -23.660  9.780   1.00 36.14  ? 50   LYS A CA    1 
ATOM   421   C C     . LYS A 1 50  ? -35.490  -23.746  8.381   1.00 40.96  ? 50   LYS A C     1 
ATOM   422   O O     . LYS A 1 50  ? -35.431  -22.725  7.698   1.00 34.89  ? 50   LYS A O     1 
ATOM   423   C CB    . LYS A 1 50  ? -35.104  -22.966  10.727  1.00 40.91  ? 50   LYS A CB    1 
ATOM   424   C CG    . LYS A 1 50  ? -35.806  -22.555  11.999  1.00 45.96  ? 50   LYS A CG    1 
ATOM   425   C CD    . LYS A 1 50  ? -34.824  -22.089  13.053  1.00 57.09  ? 50   LYS A CD    1 
ATOM   426   C CE    . LYS A 1 50  ? -35.672  -21.495  14.129  1.00 67.67  ? 50   LYS A CE    1 
ATOM   427   N NZ    . LYS A 1 50  ? -34.839  -21.063  15.249  1.00 63.27  ? 50   LYS A NZ    1 
ATOM   428   N N     . THR A 1 51  ? -35.045  -24.950  7.971   1.00 34.16  ? 51   THR A N     1 
ATOM   429   C CA    . THR A 1 51  ? -34.466  -25.114  6.642   1.00 34.46  ? 51   THR A CA    1 
ATOM   430   C C     . THR A 1 51  ? -35.383  -25.952  5.745   1.00 35.75  ? 51   THR A C     1 
ATOM   431   O O     . THR A 1 51  ? -34.969  -26.395  4.687   1.00 38.25  ? 51   THR A O     1 
ATOM   432   C CB    . THR A 1 51  ? -33.037  -25.656  6.743   1.00 32.84  ? 51   THR A CB    1 
ATOM   433   O OG1   . THR A 1 51  ? -33.114  -26.684  7.727   1.00 35.69  ? 51   THR A OG1   1 
ATOM   434   C CG2   . THR A 1 51  ? -32.041  -24.596  7.206   1.00 27.33  ? 51   THR A CG2   1 
ATOM   435   N N     . PHE A 1 52  ? -36.635  -26.169  6.173   1.00 32.96  ? 52   PHE A N     1 
ATOM   436   C CA    . PHE A 1 52  ? -37.600  -26.898  5.363   1.00 27.95  ? 52   PHE A CA    1 
ATOM   437   C C     . PHE A 1 52  ? -38.243  -25.930  4.367   1.00 28.31  ? 52   PHE A C     1 
ATOM   438   O O     . PHE A 1 52  ? -39.301  -25.346  4.657   1.00 30.78  ? 52   PHE A O     1 
ATOM   439   C CB    . PHE A 1 52  ? -38.660  -27.562  6.245   1.00 27.34  ? 52   PHE A CB    1 
ATOM   440   C CG    . PHE A 1 52  ? -39.622  -28.490  5.510   1.00 28.61  ? 52   PHE A CG    1 
ATOM   441   C CD1   . PHE A 1 52  ? -39.258  -29.804  5.200   1.00 29.04  ? 52   PHE A CD1   1 
ATOM   442   C CD2   . PHE A 1 52  ? -40.901  -28.075  5.146   1.00 27.63  ? 52   PHE A CD2   1 
ATOM   443   C CE1   . PHE A 1 52  ? -40.129  -30.683  4.545   1.00 24.92  ? 52   PHE A CE1   1 
ATOM   444   C CE2   . PHE A 1 52  ? -41.770  -28.944  4.482   1.00 32.12  ? 52   PHE A CE2   1 
ATOM   445   C CZ    . PHE A 1 52  ? -41.380  -30.245  4.172   1.00 30.28  ? 52   PHE A CZ    1 
ATOM   446   N N     . THR A 1 53  ? -37.617  -25.782  3.188   1.00 24.41  ? 53   THR A N     1 
ATOM   447   C CA    . THR A 1 53  ? -38.073  -24.801  2.203   1.00 26.98  ? 53   THR A CA    1 
ATOM   448   C C     . THR A 1 53  ? -39.049  -25.420  1.209   1.00 25.39  ? 53   THR A C     1 
ATOM   449   O O     . THR A 1 53  ? -39.767  -24.697  0.519   1.00 24.98  ? 53   THR A O     1 
ATOM   450   C CB    . THR A 1 53  ? -36.884  -24.217  1.427   1.00 27.30  ? 53   THR A CB    1 
ATOM   451   O OG1   . THR A 1 53  ? -36.355  -25.367  0.761   1.00 29.23  ? 53   THR A OG1   1 
ATOM   452   C CG2   . THR A 1 53  ? -35.820  -23.577  2.300   1.00 21.98  ? 53   THR A CG2   1 
ATOM   453   N N     . ALA A 1 54  ? -39.002  -26.745  1.057   1.00 25.93  ? 54   ALA A N     1 
ATOM   454   C CA    . ALA A 1 54  ? -39.714  -27.455  0.002   1.00 24.62  ? 54   ALA A CA    1 
ATOM   455   C C     . ALA A 1 54  ? -39.384  -26.879  -1.368  1.00 25.89  ? 54   ALA A C     1 
ATOM   456   O O     . ALA A 1 54  ? -40.219  -26.943  -2.260  1.00 26.38  ? 54   ALA A O     1 
ATOM   457   C CB    . ALA A 1 54  ? -41.206  -27.414  0.230   1.00 21.36  ? 54   ALA A CB    1 
ATOM   458   N N     . ALA A 1 55  ? -38.163  -26.358  -1.540  1.00 27.61  ? 55   ALA A N     1 
ATOM   459   C CA    . ALA A 1 55  ? -37.807  -25.644  -2.766  1.00 29.85  ? 55   ALA A CA    1 
ATOM   460   C C     . ALA A 1 55  ? -37.908  -26.535  -4.016  1.00 30.33  ? 55   ALA A C     1 
ATOM   461   O O     . ALA A 1 55  ? -38.005  -26.027  -5.120  1.00 28.38  ? 55   ALA A O     1 
ATOM   462   C CB    . ALA A 1 55  ? -36.425  -25.018  -2.637  1.00 23.84  ? 55   ALA A CB    1 
ATOM   463   N N     . GLN A 1 56  ? -37.847  -27.863  -3.879  1.00 28.79  ? 56   GLN A N     1 
ATOM   464   C CA    . GLN A 1 56  ? -37.886  -28.681  -5.090  1.00 28.28  ? 56   GLN A CA    1 
ATOM   465   C C     . GLN A 1 56  ? -39.094  -29.592  -5.105  1.00 26.24  ? 56   GLN A C     1 
ATOM   466   O O     . GLN A 1 56  ? -39.155  -30.520  -5.888  1.00 28.61  ? 56   GLN A O     1 
ATOM   467   C CB    . GLN A 1 56  ? -36.605  -29.479  -5.282  1.00 27.73  ? 56   GLN A CB    1 
ATOM   468   C CG    . GLN A 1 56  ? -35.519  -28.683  -5.991  1.00 40.09  ? 56   GLN A CG    1 
ATOM   469   C CD    . GLN A 1 56  ? -34.199  -28.914  -5.315  1.00 52.50  ? 56   GLN A CD    1 
ATOM   470   O OE1   . GLN A 1 56  ? -33.483  -29.874  -5.618  1.00 54.25  ? 56   GLN A OE1   1 
ATOM   471   N NE2   . GLN A 1 56  ? -33.933  -28.083  -4.317  1.00 67.74  ? 56   GLN A NE2   1 
ATOM   472   N N     . PHE A 1 57  ? -40.065  -29.325  -4.236  1.00 28.71  ? 57   PHE A N     1 
ATOM   473   C CA    . PHE A 1 57  ? -41.244  -30.157  -4.217  1.00 25.18  ? 57   PHE A CA    1 
ATOM   474   C C     . PHE A 1 57  ? -42.173  -29.672  -5.313  1.00 28.18  ? 57   PHE A C     1 
ATOM   475   O O     . PHE A 1 57  ? -42.621  -28.529  -5.287  1.00 34.15  ? 57   PHE A O     1 
ATOM   476   C CB    . PHE A 1 57  ? -41.942  -30.100  -2.863  1.00 23.32  ? 57   PHE A CB    1 
ATOM   477   C CG    . PHE A 1 57  ? -43.211  -30.934  -2.812  1.00 22.50  ? 57   PHE A CG    1 
ATOM   478   C CD1   . PHE A 1 57  ? -43.159  -32.333  -2.764  1.00 25.59  ? 57   PHE A CD1   1 
ATOM   479   C CD2   . PHE A 1 57  ? -44.453  -30.324  -2.782  1.00 22.88  ? 57   PHE A CD2   1 
ATOM   480   C CE1   . PHE A 1 57  ? -44.324  -33.100  -2.688  1.00 25.56  ? 57   PHE A CE1   1 
ATOM   481   C CE2   . PHE A 1 57  ? -45.625  -31.094  -2.712  1.00 24.83  ? 57   PHE A CE2   1 
ATOM   482   C CZ    . PHE A 1 57  ? -45.564  -32.480  -2.651  1.00 24.52  ? 57   PHE A CZ    1 
ATOM   483   N N     . ASP A 1 58  ? -42.480  -30.577  -6.251  1.00 27.60  ? 58   ASP A N     1 
ATOM   484   C CA    . ASP A 1 58  ? -43.391  -30.240  -7.318  1.00 28.40  ? 58   ASP A CA    1 
ATOM   485   C C     . ASP A 1 58  ? -44.453  -31.327  -7.398  1.00 28.54  ? 58   ASP A C     1 
ATOM   486   O O     . ASP A 1 58  ? -44.213  -32.387  -7.980  1.00 30.83  ? 58   ASP A O     1 
ATOM   487   C CB    . ASP A 1 58  ? -42.619  -30.032  -8.614  1.00 33.28  ? 58   ASP A CB    1 
ATOM   488   C CG    . ASP A 1 58  ? -43.450  -29.602  -9.824  1.00 36.83  ? 58   ASP A CG    1 
ATOM   489   O OD1   . ASP A 1 58  ? -44.718  -29.612  -9.756  1.00 36.68  ? 58   ASP A OD1   1 
ATOM   490   O OD2   . ASP A 1 58  ? -42.797  -29.253  -10.830 1.00 47.45  ? 58   ASP A OD2   1 
ATOM   491   N N     . ALA A 1 59  ? -45.636  -31.040  -6.834  1.00 26.39  ? 59   ALA A N     1 
ATOM   492   C CA    . ALA A 1 59  ? -46.638  -32.078  -6.698  1.00 25.98  ? 59   ALA A CA    1 
ATOM   493   C C     . ALA A 1 59  ? -47.086  -32.536  -8.081  1.00 26.87  ? 59   ALA A C     1 
ATOM   494   O O     . ALA A 1 59  ? -47.470  -33.697  -8.244  1.00 27.93  ? 59   ALA A O     1 
ATOM   495   C CB    . ALA A 1 59  ? -47.812  -31.609  -5.866  1.00 24.62  ? 59   ALA A CB    1 
ATOM   496   N N     . LYS A 1 60  ? -47.042  -31.616  -9.071  1.00 30.64  ? 60   LYS A N     1 
ATOM   497   C CA    . LYS A 1 60  ? -47.491  -31.947  -10.418 1.00 32.03  ? 60   LYS A CA    1 
ATOM   498   C C     . LYS A 1 60  ? -46.546  -32.987  -11.019 1.00 29.62  ? 60   LYS A C     1 
ATOM   499   O O     . LYS A 1 60  ? -47.010  -33.944  -11.644 1.00 28.36  ? 60   LYS A O     1 
ATOM   500   C CB    . LYS A 1 60  ? -47.683  -30.696  -11.275 1.00 37.94  ? 60   LYS A CB    1 
ATOM   501   C CG    . LYS A 1 60  ? -48.088  -30.706  -12.750 1.00 65.45  ? 60   LYS A CG    1 
ATOM   502   C CD    . LYS A 1 60  ? -49.121  -29.628  -13.123 1.00 92.64  ? 60   LYS A CD    1 
ATOM   503   C CE    . LYS A 1 60  ? -48.975  -28.810  -14.400 1.00 88.89  ? 60   LYS A CE    1 
ATOM   504   N NZ    . LYS A 1 60  ? -48.171  -29.457  -15.440 1.00 76.28  ? 60   LYS A NZ    1 
ATOM   505   N N     . LYS A 1 61  ? -45.233  -32.799  -10.812 1.00 27.37  ? 61   LYS A N     1 
ATOM   506   C CA    . LYS A 1 61  ? -44.257  -33.732  -11.336 1.00 29.28  ? 61   LYS A CA    1 
ATOM   507   C C     . LYS A 1 61  ? -44.430  -35.094  -10.666 1.00 27.69  ? 61   LYS A C     1 
ATOM   508   O O     . LYS A 1 61  ? -44.372  -36.113  -11.354 1.00 28.09  ? 61   LYS A O     1 
ATOM   509   C CB    . LYS A 1 61  ? -42.804  -33.261  -11.205 1.00 37.96  ? 61   LYS A CB    1 
ATOM   510   C CG    . LYS A 1 61  ? -42.211  -32.368  -12.259 1.00 57.31  ? 61   LYS A CG    1 
ATOM   511   C CD    . LYS A 1 61  ? -40.694  -32.370  -12.023 1.00 73.77  ? 61   LYS A CD    1 
ATOM   512   C CE    . LYS A 1 61  ? -40.335  -33.756  -11.489 1.00 68.55  ? 61   LYS A CE    1 
ATOM   513   N NZ    . LYS A 1 61  ? -38.979  -34.234  -11.752 1.00 58.79  ? 61   LYS A NZ    1 
ATOM   514   N N     . ILE A 1 62  ? -44.684  -35.102  -9.351  1.00 22.97  ? 62   ILE A N     1 
ATOM   515   C CA    . ILE A 1 62  ? -44.846  -36.349  -8.641  1.00 24.14  ? 62   ILE A CA    1 
ATOM   516   C C     . ILE A 1 62  ? -46.083  -37.083  -9.156  1.00 24.41  ? 62   ILE A C     1 
ATOM   517   O O     . ILE A 1 62  ? -46.018  -38.274  -9.437  1.00 23.41  ? 62   ILE A O     1 
ATOM   518   C CB    . ILE A 1 62  ? -44.875  -36.109  -7.129  1.00 24.18  ? 62   ILE A CB    1 
ATOM   519   C CG1   . ILE A 1 62  ? -43.491  -35.664  -6.666  1.00 25.65  ? 62   ILE A CG1   1 
ATOM   520   C CG2   . ILE A 1 62  ? -45.348  -37.361  -6.381  1.00 19.36  ? 62   ILE A CG2   1 
ATOM   521   C CD1   . ILE A 1 62  ? -43.456  -35.166  -5.220  1.00 25.57  ? 62   ILE A CD1   1 
ATOM   522   N N     . ALA A 1 63  ? -47.199  -36.373  -9.330  1.00 21.49  ? 63   ALA A N     1 
ATOM   523   C CA    . ALA A 1 63  ? -48.409  -37.025  -9.807  1.00 21.52  ? 63   ALA A CA    1 
ATOM   524   C C     . ALA A 1 63  ? -48.221  -37.552  -11.237 1.00 21.36  ? 63   ALA A C     1 
ATOM   525   O O     . ALA A 1 63  ? -48.655  -38.665  -11.533 1.00 19.87  ? 63   ALA A O     1 
ATOM   526   C CB    . ALA A 1 63  ? -49.565  -36.077  -9.682  1.00 18.56  ? 63   ALA A CB    1 
ATOM   527   N N     . HIS A 1 64  ? -47.546  -36.779  -12.094 1.00 21.49  ? 64   HIS A N     1 
ATOM   528   C CA    . HIS A 1 64  ? -47.258  -37.217  -13.462 1.00 25.28  ? 64   HIS A CA    1 
ATOM   529   C C     . HIS A 1 64  ? -46.426  -38.512  -13.447 1.00 25.46  ? 64   HIS A C     1 
ATOM   530   O O     . HIS A 1 64  ? -46.740  -39.490  -14.137 1.00 28.08  ? 64   HIS A O     1 
ATOM   531   C CB    . HIS A 1 64  ? -46.667  -36.084  -14.316 1.00 23.51  ? 64   HIS A CB    1 
ATOM   532   C CG    . HIS A 1 64  ? -47.703  -35.181  -14.918 1.00 29.69  ? 64   HIS A CG    1 
ATOM   533   N ND1   . HIS A 1 64  ? -48.473  -34.248  -14.233 1.00 37.47  ? 64   HIS A ND1   1 
ATOM   534   C CD2   . HIS A 1 64  ? -48.122  -35.112  -16.152 1.00 33.35  ? 64   HIS A CD2   1 
ATOM   535   C CE1   . HIS A 1 64  ? -49.320  -33.638  -15.044 1.00 31.68  ? 64   HIS A CE1   1 
ATOM   536   N NE2   . HIS A 1 64  ? -49.109  -34.122  -16.218 1.00 34.12  ? 64   HIS A NE2   1 
ATOM   537   N N     . ALA A 1 65  ? -45.364  -38.519  -12.639 1.00 23.18  ? 65   ALA A N     1 
ATOM   538   C CA    . ALA A 1 65  ? -44.514  -39.691  -12.539 1.00 23.88  ? 65   ALA A CA    1 
ATOM   539   C C     . ALA A 1 65  ? -45.317  -40.897  -12.014 1.00 24.02  ? 65   ALA A C     1 
ATOM   540   O O     . ALA A 1 65  ? -45.149  -42.004  -12.497 1.00 27.24  ? 65   ALA A O     1 
ATOM   541   C CB    . ALA A 1 65  ? -43.312  -39.355  -11.666 1.00 21.53  ? 65   ALA A CB    1 
ATOM   542   N N     . ALA A 1 66  ? -46.202  -40.705  -11.034 1.00 19.92  ? 66   ALA A N     1 
ATOM   543   C CA    . ALA A 1 66  ? -47.034  -41.800  -10.543 1.00 22.33  ? 66   ALA A CA    1 
ATOM   544   C C     . ALA A 1 66  ? -47.932  -42.364  -11.652 1.00 23.32  ? 66   ALA A C     1 
ATOM   545   O O     . ALA A 1 66  ? -48.079  -43.587  -11.797 1.00 21.42  ? 66   ALA A O     1 
ATOM   546   C CB    . ALA A 1 66  ? -47.837  -41.367  -9.344  1.00 18.76  ? 66   ALA A CB    1 
ATOM   547   N N     . LYS A 1 67  ? -48.514  -41.464  -12.454 1.00 22.85  ? 67   LYS A N     1 
ATOM   548   C CA    . LYS A 1 67  ? -49.348  -41.877  -13.572 1.00 25.54  ? 67   LYS A CA    1 
ATOM   549   C C     . LYS A 1 67  ? -48.519  -42.696  -14.567 1.00 25.62  ? 67   LYS A C     1 
ATOM   550   O O     . LYS A 1 67  ? -48.938  -43.767  -14.967 1.00 27.15  ? 67   LYS A O     1 
ATOM   551   C CB    . LYS A 1 67  ? -50.080  -40.701  -14.227 1.00 29.77  ? 67   LYS A CB    1 
ATOM   552   C CG    . LYS A 1 67  ? -51.140  -41.174  -15.234 1.00 34.61  ? 67   LYS A CG    1 
ATOM   553   C CD    . LYS A 1 67  ? -52.058  -40.231  -16.017 1.00 38.77  ? 67   LYS A CD    1 
ATOM   554   C CE    . LYS A 1 67  ? -53.363  -41.013  -16.080 1.00 56.41  ? 67   LYS A CE    1 
ATOM   555   N NZ    . LYS A 1 67  ? -54.637  -40.306  -16.200 1.00 57.06  ? 67   LYS A NZ    1 
ATOM   556   N N     . ALA A 1 68  ? -47.335  -42.202  -14.936 1.00 26.63  ? 68   ALA A N     1 
ATOM   557   C CA    . ALA A 1 68  ? -46.433  -42.868  -15.882 1.00 27.22  ? 68   ALA A CA    1 
ATOM   558   C C     . ALA A 1 68  ? -46.002  -44.250  -15.383 1.00 25.63  ? 68   ALA A C     1 
ATOM   559   O O     . ALA A 1 68  ? -45.800  -45.144  -16.177 1.00 33.80  ? 68   ALA A O     1 
ATOM   560   C CB    . ALA A 1 68  ? -45.211  -41.998  -16.184 1.00 21.17  ? 68   ALA A CB    1 
ATOM   561   N N     . VAL A 1 69  ? -45.857  -44.442  -14.077 1.00 22.93  ? 69   VAL A N     1 
ATOM   562   C CA    . VAL A 1 69  ? -45.372  -45.707  -13.554 1.00 25.02  ? 69   VAL A CA    1 
ATOM   563   C C     . VAL A 1 69  ? -46.545  -46.699  -13.483 1.00 25.60  ? 69   VAL A C     1 
ATOM   564   O O     . VAL A 1 69  ? -46.350  -47.877  -13.144 1.00 25.39  ? 69   VAL A O     1 
ATOM   565   C CB    . VAL A 1 69  ? -44.650  -45.555  -12.196 1.00 28.95  ? 69   VAL A CB    1 
ATOM   566   C CG1   . VAL A 1 69  ? -45.602  -45.479  -11.031 1.00 28.37  ? 69   VAL A CG1   1 
ATOM   567   C CG2   . VAL A 1 69  ? -43.780  -46.745  -11.855 1.00 42.31  ? 69   VAL A CG2   1 
ATOM   568   N N     . GLY A 1 70  ? -47.772  -46.228  -13.785 1.00 21.59  ? 70   GLY A N     1 
ATOM   569   C CA    . GLY A 1 70  ? -48.965  -47.067  -13.717 1.00 21.06  ? 70   GLY A CA    1 
ATOM   570   C C     . GLY A 1 70  ? -49.604  -47.150  -12.321 1.00 23.11  ? 70   GLY A C     1 
ATOM   571   O O     . GLY A 1 70  ? -50.489  -47.998  -12.112 1.00 22.35  ? 70   GLY A O     1 
ATOM   572   N N     . ALA A 1 71  ? -49.191  -46.272  -11.373 1.00 18.89  ? 71   ALA A N     1 
ATOM   573   C CA    . ALA A 1 71  ? -49.824  -46.226  -10.051 1.00 19.46  ? 71   ALA A CA    1 
ATOM   574   C C     . ALA A 1 71  ? -51.193  -45.569  -10.174 1.00 21.06  ? 71   ALA A C     1 
ATOM   575   O O     . ALA A 1 71  ? -51.386  -44.694  -11.025 1.00 25.01  ? 71   ALA A O     1 
ATOM   576   C CB    . ALA A 1 71  ? -48.948  -45.478  -9.050  1.00 16.39  ? 71   ALA A CB    1 
ATOM   577   N N     . LYS A 1 72  ? -52.147  -45.971  -9.325  1.00 20.86  ? 72   LYS A N     1 
ATOM   578   C CA    . LYS A 1 72  ? -53.488  -45.397  -9.366  1.00 22.98  ? 72   LYS A CA    1 
ATOM   579   C C     . LYS A 1 72  ? -53.786  -44.614  -8.085  1.00 23.43  ? 72   LYS A C     1 
ATOM   580   O O     . LYS A 1 72  ? -54.858  -44.008  -7.967  1.00 23.18  ? 72   LYS A O     1 
ATOM   581   C CB    . LYS A 1 72  ? -54.524  -46.510  -9.588  1.00 27.73  ? 72   LYS A CB    1 
ATOM   582   C CG    . LYS A 1 72  ? -54.439  -47.192  -10.961 1.00 24.75  ? 72   LYS A CG    1 
ATOM   583   C CD    . LYS A 1 72  ? -54.677  -46.220  -12.095 1.00 29.24  ? 72   LYS A CD    1 
ATOM   584   C CE    . LYS A 1 72  ? -54.664  -46.735  -13.515 1.00 34.52  ? 72   LYS A CE    1 
ATOM   585   N NZ    . LYS A 1 72  ? -55.724  -47.743  -13.656 1.00 36.58  ? 72   LYS A NZ    1 
ATOM   586   N N     . TYR A 1 73  ? -52.848  -44.638  -7.124  1.00 20.52  ? 73   TYR A N     1 
ATOM   587   C CA    . TYR A 1 73  ? -52.972  -43.845  -5.912  1.00 20.74  ? 73   TYR A CA    1 
ATOM   588   C C     . TYR A 1 73  ? -51.583  -43.569  -5.355  1.00 20.43  ? 73   TYR A C     1 
ATOM   589   O O     . TYR A 1 73  ? -50.614  -44.242  -5.744  1.00 19.87  ? 73   TYR A O     1 
ATOM   590   C CB    . TYR A 1 73  ? -53.846  -44.549  -4.874  1.00 22.94  ? 73   TYR A CB    1 
ATOM   591   C CG    . TYR A 1 73  ? -53.392  -45.887  -4.283  1.00 22.51  ? 73   TYR A CG    1 
ATOM   592   C CD1   . TYR A 1 73  ? -53.267  -47.027  -5.084  1.00 18.47  ? 73   TYR A CD1   1 
ATOM   593   C CD2   . TYR A 1 73  ? -53.199  -46.029  -2.904  1.00 21.77  ? 73   TYR A CD2   1 
ATOM   594   C CE1   . TYR A 1 73  ? -52.947  -48.261  -4.526  1.00 19.02  ? 73   TYR A CE1   1 
ATOM   595   C CE2   . TYR A 1 73  ? -52.903  -47.257  -2.330  1.00 20.54  ? 73   TYR A CE2   1 
ATOM   596   C CZ    . TYR A 1 73  ? -52.787  -48.381  -3.149  1.00 21.96  ? 73   TYR A CZ    1 
ATOM   597   O OH    . TYR A 1 73  ? -52.500  -49.593  -2.584  1.00 21.43  ? 73   TYR A OH    1 
ATOM   598   N N     . ILE A 1 74  ? -51.514  -42.552  -4.479  1.00 18.59  ? 74   ILE A N     1 
ATOM   599   C CA    . ILE A 1 74  ? -50.282  -42.173  -3.813  1.00 18.39  ? 74   ILE A CA    1 
ATOM   600   C C     . ILE A 1 74  ? -50.565  -42.023  -2.325  1.00 20.84  ? 74   ILE A C     1 
ATOM   601   O O     . ILE A 1 74  ? -51.544  -41.378  -1.932  1.00 20.75  ? 74   ILE A O     1 
ATOM   602   C CB    . ILE A 1 74  ? -49.729  -40.860  -4.384  1.00 18.43  ? 74   ILE A CB    1 
ATOM   603   C CG1   . ILE A 1 74  ? -49.566  -40.900  -5.916  1.00 18.24  ? 74   ILE A CG1   1 
ATOM   604   C CG2   . ILE A 1 74  ? -48.401  -40.532  -3.711  1.00 17.47  ? 74   ILE A CG2   1 
ATOM   605   C CD1   . ILE A 1 74  ? -49.193  -39.549  -6.500  1.00 18.37  ? 74   ILE A CD1   1 
ATOM   606   N N     . VAL A 1 75  ? -49.721  -42.653  -1.500  1.00 20.91  ? 75   VAL A N     1 
ATOM   607   C CA    . VAL A 1 75  ? -49.755  -42.458  -0.066  1.00 19.48  ? 75   VAL A CA    1 
ATOM   608   C C     . VAL A 1 75  ? -48.607  -41.526  0.302   1.00 21.80  ? 75   VAL A C     1 
ATOM   609   O O     . VAL A 1 75  ? -47.447  -41.910  0.122   1.00 24.64  ? 75   VAL A O     1 
ATOM   610   C CB    . VAL A 1 75  ? -49.607  -43.821  0.634   1.00 18.97  ? 75   VAL A CB    1 
ATOM   611   C CG1   . VAL A 1 75  ? -49.693  -43.653  2.160   1.00 16.24  ? 75   VAL A CG1   1 
ATOM   612   C CG2   . VAL A 1 75  ? -50.681  -44.799  0.147   1.00 17.90  ? 75   VAL A CG2   1 
ATOM   613   N N     . LEU A 1 76  ? -48.934  -40.317  0.797   1.00 20.39  ? 76   LEU A N     1 
ATOM   614   C CA    . LEU A 1 76  ? -47.932  -39.346  1.226   1.00 19.40  ? 76   LEU A CA    1 
ATOM   615   C C     . LEU A 1 76  ? -47.911  -39.249  2.749   1.00 20.13  ? 76   LEU A C     1 
ATOM   616   O O     . LEU A 1 76  ? -48.967  -39.201  3.402   1.00 23.52  ? 76   LEU A O     1 
ATOM   617   C CB    . LEU A 1 76  ? -48.207  -37.989  0.575   1.00 21.28  ? 76   LEU A CB    1 
ATOM   618   C CG    . LEU A 1 76  ? -47.292  -36.829  0.973   1.00 21.25  ? 76   LEU A CG    1 
ATOM   619   C CD1   . LEU A 1 76  ? -45.831  -37.120  0.607   1.00 21.69  ? 76   LEU A CD1   1 
ATOM   620   C CD2   . LEU A 1 76  ? -47.737  -35.569  0.279   1.00 19.32  ? 76   LEU A CD2   1 
ATOM   621   N N     . THR A 1 77  ? -46.696  -39.240  3.330   1.00 20.28  ? 77   THR A N     1 
ATOM   622   C CA    . THR A 1 77  ? -46.553  -39.054  4.769   1.00 20.03  ? 77   THR A CA    1 
ATOM   623   C C     . THR A 1 77  ? -47.000  -37.626  5.117   1.00 23.31  ? 77   THR A C     1 
ATOM   624   O O     . THR A 1 77  ? -46.294  -36.663  4.788   1.00 24.77  ? 77   THR A O     1 
ATOM   625   C CB    . THR A 1 77  ? -45.104  -39.298  5.204   1.00 19.93  ? 77   THR A CB    1 
ATOM   626   O OG1   . THR A 1 77  ? -44.240  -38.489  4.411   1.00 19.52  ? 77   THR A OG1   1 
ATOM   627   C CG2   . THR A 1 77  ? -44.688  -40.756  5.131   1.00 20.03  ? 77   THR A CG2   1 
ATOM   628   N N     . THR A 1 78  ? -48.153  -37.473  5.790   1.00 21.82  ? 78   THR A N     1 
ATOM   629   C CA    . THR A 1 78  ? -48.591  -36.133  6.172   1.00 22.15  ? 78   THR A CA    1 
ATOM   630   C C     . THR A 1 78  ? -47.986  -35.748  7.524   1.00 23.02  ? 78   THR A C     1 
ATOM   631   O O     . THR A 1 78  ? -47.863  -34.553  7.821   1.00 27.58  ? 78   THR A O     1 
ATOM   632   C CB    . THR A 1 78  ? -50.119  -36.011  6.190   1.00 21.83  ? 78   THR A CB    1 
ATOM   633   O OG1   . THR A 1 78  ? -50.582  -36.769  7.311   1.00 22.83  ? 78   THR A OG1   1 
ATOM   634   C CG2   . THR A 1 78  ? -50.764  -36.416  4.873   1.00 20.09  ? 78   THR A CG2   1 
ATOM   635   N N     . LYS A 1 79  ? -47.654  -36.757  8.347   1.00 22.88  ? 79   LYS A N     1 
ATOM   636   C CA    . LYS A 1 79  ? -46.981  -36.582  9.633   1.00 23.23  ? 79   LYS A CA    1 
ATOM   637   C C     . LYS A 1 79  ? -46.384  -37.927  10.025  1.00 23.07  ? 79   LYS A C     1 
ATOM   638   O O     . LYS A 1 79  ? -47.134  -38.895  10.193  1.00 22.83  ? 79   LYS A O     1 
ATOM   639   C CB    . LYS A 1 79  ? -47.961  -36.144  10.737  1.00 24.82  ? 79   LYS A CB    1 
ATOM   640   C CG    . LYS A 1 79  ? -47.280  -35.726  12.059  1.00 24.36  ? 79   LYS A CG    1 
ATOM   641   C CD    . LYS A 1 79  ? -48.077  -35.966  13.348  1.00 25.66  ? 79   LYS A CD    1 
ATOM   642   C CE    . LYS A 1 79  ? -48.186  -37.426  13.677  1.00 26.91  ? 79   LYS A CE    1 
ATOM   643   N NZ    . LYS A 1 79  ? -48.912  -37.719  14.934  1.00 25.69  ? 79   LYS A NZ    1 
ATOM   644   N N     . HIS A 1 80  ? -45.048  -37.990  10.171  1.00 25.69  ? 80   HIS A N     1 
ATOM   645   C CA    . HIS A 1 80  ? -44.367  -39.230  10.560  1.00 23.52  ? 80   HIS A CA    1 
ATOM   646   C C     . HIS A 1 80  ? -44.127  -39.219  12.080  1.00 24.77  ? 80   HIS A C     1 
ATOM   647   O O     . HIS A 1 80  ? -44.618  -38.321  12.775  1.00 24.84  ? 80   HIS A O     1 
ATOM   648   C CB    . HIS A 1 80  ? -43.137  -39.454  9.661   1.00 22.48  ? 80   HIS A CB    1 
ATOM   649   C CG    . HIS A 1 80  ? -42.782  -40.900  9.520   1.00 23.22  ? 80   HIS A CG    1 
ATOM   650   N ND1   . HIS A 1 80  ? -41.958  -41.577  10.416  1.00 22.48  ? 80   HIS A ND1   1 
ATOM   651   C CD2   . HIS A 1 80  ? -43.185  -41.800  8.575   1.00 20.38  ? 80   HIS A CD2   1 
ATOM   652   C CE1   . HIS A 1 80  ? -41.878  -42.858  10.031  1.00 25.20  ? 80   HIS A CE1   1 
ATOM   653   N NE2   . HIS A 1 80  ? -42.607  -43.013  8.897   1.00 22.55  ? 80   HIS A NE2   1 
ATOM   654   N N     . HIS A 1 81  ? -43.348  -40.180  12.615  1.00 21.28  ? 81   HIS A N     1 
ATOM   655   C CA    . HIS A 1 81  ? -43.118  -40.233  14.051  1.00 22.91  ? 81   HIS A CA    1 
ATOM   656   C C     . HIS A 1 81  ? -42.533  -38.926  14.583  1.00 25.21  ? 81   HIS A C     1 
ATOM   657   O O     . HIS A 1 81  ? -42.835  -38.504  15.700  1.00 26.82  ? 81   HIS A O     1 
ATOM   658   C CB    . HIS A 1 81  ? -42.217  -41.411  14.436  1.00 24.72  ? 81   HIS A CB    1 
ATOM   659   C CG    . HIS A 1 81  ? -42.731  -42.726  13.960  1.00 30.31  ? 81   HIS A CG    1 
ATOM   660   N ND1   . HIS A 1 81  ? -44.027  -43.112  14.212  1.00 36.26  ? 81   HIS A ND1   1 
ATOM   661   C CD2   . HIS A 1 81  ? -42.174  -43.733  13.265  1.00 28.51  ? 81   HIS A CD2   1 
ATOM   662   C CE1   . HIS A 1 81  ? -44.243  -44.309  13.672  1.00 31.13  ? 81   HIS A CE1   1 
ATOM   663   N NE2   . HIS A 1 81  ? -43.133  -44.694  13.105  1.00 29.60  ? 81   HIS A NE2   1 
ATOM   664   N N     . GLU A 1 82  ? -41.668  -38.286  13.803  1.00 23.23  ? 82   GLU A N     1 
ATOM   665   C CA    . GLU A 1 82  ? -41.047  -37.045  14.229  1.00 25.31  ? 82   GLU A CA    1 
ATOM   666   C C     . GLU A 1 82  ? -42.119  -36.007  14.589  1.00 28.95  ? 82   GLU A C     1 
ATOM   667   O O     . GLU A 1 82  ? -41.809  -35.033  15.272  1.00 27.77  ? 82   GLU A O     1 
ATOM   668   C CB    . GLU A 1 82  ? -40.094  -36.490  13.159  1.00 25.48  ? 82   GLU A CB    1 
ATOM   669   C CG    . GLU A 1 82  ? -40.805  -36.280  11.818  1.00 22.18  ? 82   GLU A CG    1 
ATOM   670   C CD    . GLU A 1 82  ? -40.033  -35.556  10.725  1.00 25.24  ? 82   GLU A CD    1 
ATOM   671   O OE1   . GLU A 1 82  ? -38.768  -35.449  10.788  1.00 23.94  ? 82   GLU A OE1   1 
ATOM   672   O OE2   . GLU A 1 82  ? -40.734  -35.054  9.786   1.00 26.37  ? 82   GLU A OE2   1 
ATOM   673   N N     . GLY A 1 83  ? -43.346  -36.144  14.046  1.00 29.04  ? 83   GLY A N     1 
ATOM   674   C CA    . GLY A 1 83  ? -44.472  -35.344  14.511  1.00 23.74  ? 83   GLY A CA    1 
ATOM   675   C C     . GLY A 1 83  ? -44.620  -34.006  13.774  1.00 26.99  ? 83   GLY A C     1 
ATOM   676   O O     . GLY A 1 83  ? -45.459  -33.187  14.167  1.00 26.87  ? 83   GLY A O     1 
ATOM   677   N N     . PHE A 1 84  ? -43.833  -33.775  12.697  1.00 21.55  ? 84   PHE A N     1 
ATOM   678   C CA    . PHE A 1 84  ? -43.965  -32.553  11.905  1.00 20.14  ? 84   PHE A CA    1 
ATOM   679   C C     . PHE A 1 84  ? -45.034  -32.717  10.824  1.00 24.93  ? 84   PHE A C     1 
ATOM   680   O O     . PHE A 1 84  ? -45.058  -33.721  10.109  1.00 29.19  ? 84   PHE A O     1 
ATOM   681   C CB    . PHE A 1 84  ? -42.592  -32.295  11.290  1.00 19.46  ? 84   PHE A CB    1 
ATOM   682   C CG    . PHE A 1 84  ? -42.628  -31.200  10.232  1.00 22.36  ? 84   PHE A CG    1 
ATOM   683   C CD1   . PHE A 1 84  ? -42.740  -29.861  10.599  1.00 20.22  ? 84   PHE A CD1   1 
ATOM   684   C CD2   . PHE A 1 84  ? -42.530  -31.510  8.874   1.00 21.42  ? 84   PHE A CD2   1 
ATOM   685   C CE1   . PHE A 1 84  ? -42.748  -28.858  9.625   1.00 20.86  ? 84   PHE A CE1   1 
ATOM   686   C CE2   . PHE A 1 84  ? -42.547  -30.507  7.906   1.00 21.53  ? 84   PHE A CE2   1 
ATOM   687   C CZ    . PHE A 1 84  ? -42.678  -29.184  8.280   1.00 22.29  ? 84   PHE A CZ    1 
ATOM   688   N N     . PHE A 1 85  ? -45.908  -31.718  10.669  1.00 25.39  ? 85   PHE A N     1 
ATOM   689   C CA    . PHE A 1 85  ? -47.043  -31.841  9.766   1.00 23.98  ? 85   PHE A CA    1 
ATOM   690   C C     . PHE A 1 85  ? -46.776  -31.125  8.442   1.00 24.57  ? 85   PHE A C     1 
ATOM   691   O O     . PHE A 1 85  ? -46.348  -29.959  8.421   1.00 23.43  ? 85   PHE A O     1 
ATOM   692   C CB    . PHE A 1 85  ? -48.295  -31.197  10.369  1.00 24.36  ? 85   PHE A CB    1 
ATOM   693   C CG    . PHE A 1 85  ? -48.770  -31.758  11.703  1.00 22.29  ? 85   PHE A CG    1 
ATOM   694   C CD1   . PHE A 1 85  ? -48.246  -31.276  12.915  1.00 23.07  ? 85   PHE A CD1   1 
ATOM   695   C CD2   . PHE A 1 85  ? -49.774  -32.717  11.739  1.00 19.51  ? 85   PHE A CD2   1 
ATOM   696   C CE1   . PHE A 1 85  ? -48.706  -31.780  14.129  1.00 21.45  ? 85   PHE A CE1   1 
ATOM   697   C CE2   . PHE A 1 85  ? -50.226  -33.221  12.955  1.00 23.31  ? 85   PHE A CE2   1 
ATOM   698   C CZ    . PHE A 1 85  ? -49.693  -32.740  14.153  1.00 21.31  ? 85   PHE A CZ    1 
ATOM   699   N N     . LEU A 1 86  ? -47.075  -31.826  7.339   1.00 20.98  ? 86   LEU A N     1 
ATOM   700   C CA    . LEU A 1 86  ? -46.821  -31.270  6.017   1.00 23.56  ? 86   LEU A CA    1 
ATOM   701   C C     . LEU A 1 86  ? -48.006  -30.433  5.520   1.00 27.50  ? 86   LEU A C     1 
ATOM   702   O O     . LEU A 1 86  ? -48.068  -30.056  4.344   1.00 27.09  ? 86   LEU A O     1 
ATOM   703   C CB    . LEU A 1 86  ? -46.460  -32.383  5.042   1.00 20.09  ? 86   LEU A CB    1 
ATOM   704   C CG    . LEU A 1 86  ? -44.978  -32.791  5.012   1.00 23.30  ? 86   LEU A CG    1 
ATOM   705   C CD1   . LEU A 1 86  ? -44.557  -33.575  6.260   1.00 19.13  ? 86   LEU A CD1   1 
ATOM   706   C CD2   . LEU A 1 86  ? -44.789  -33.618  3.757   1.00 19.66  ? 86   LEU A CD2   1 
ATOM   707   N N     . TYR A 1 87  ? -48.960  -30.141  6.411   1.00 24.95  ? 87   TYR A N     1 
ATOM   708   C CA    . TYR A 1 87  ? -50.114  -29.340  6.029   1.00 26.49  ? 87   TYR A CA    1 
ATOM   709   C C     . TYR A 1 87  ? -50.410  -28.280  7.099   1.00 27.66  ? 87   TYR A C     1 
ATOM   710   O O     . TYR A 1 87  ? -49.803  -28.285  8.176   1.00 24.20  ? 87   TYR A O     1 
ATOM   711   C CB    . TYR A 1 87  ? -51.324  -30.254  5.824   1.00 23.97  ? 87   TYR A CB    1 
ATOM   712   C CG    . TYR A 1 87  ? -51.712  -31.113  7.021   1.00 23.95  ? 87   TYR A CG    1 
ATOM   713   C CD1   . TYR A 1 87  ? -51.009  -32.272  7.335   1.00 22.59  ? 87   TYR A CD1   1 
ATOM   714   C CD2   . TYR A 1 87  ? -52.811  -30.782  7.830   1.00 23.47  ? 87   TYR A CD2   1 
ATOM   715   C CE1   . TYR A 1 87  ? -51.367  -33.072  8.422   1.00 23.12  ? 87   TYR A CE1   1 
ATOM   716   C CE2   . TYR A 1 87  ? -53.203  -31.582  8.900   1.00 23.17  ? 87   TYR A CE2   1 
ATOM   717   C CZ    . TYR A 1 87  ? -52.489  -32.748  9.187   1.00 23.89  ? 87   TYR A CZ    1 
ATOM   718   O OH    . TYR A 1 87  ? -52.847  -33.584  10.224  1.00 21.63  ? 87   TYR A OH    1 
ATOM   719   N N     . ASP A 1 88  ? -51.375  -27.395  6.802   1.00 28.17  ? 88   ASP A N     1 
ATOM   720   C CA    . ASP A 1 88  ? -51.790  -26.368  7.735   1.00 30.03  ? 88   ASP A CA    1 
ATOM   721   C C     . ASP A 1 88  ? -52.676  -26.973  8.824   1.00 25.89  ? 88   ASP A C     1 
ATOM   722   O O     . ASP A 1 88  ? -53.823  -27.338  8.565   1.00 25.02  ? 88   ASP A O     1 
ATOM   723   C CB    . ASP A 1 88  ? -52.545  -25.293  6.986   1.00 32.29  ? 88   ASP A CB    1 
ATOM   724   C CG    . ASP A 1 88  ? -52.925  -24.061  7.798   1.00 37.05  ? 88   ASP A CG    1 
ATOM   725   O OD1   . ASP A 1 88  ? -52.905  -24.115  9.062   1.00 34.04  ? 88   ASP A OD1   1 
ATOM   726   O OD2   . ASP A 1 88  ? -53.199  -23.039  7.134   1.00 38.29  ? 88   ASP A OD2   1 
ATOM   727   N N     . THR A 1 89  ? -52.171  -27.039  10.056  1.00 22.52  ? 89   THR A N     1 
ATOM   728   C CA    . THR A 1 89  ? -52.954  -27.661  11.117  1.00 25.39  ? 89   THR A CA    1 
ATOM   729   C C     . THR A 1 89  ? -53.957  -26.681  11.728  1.00 27.55  ? 89   THR A C     1 
ATOM   730   O O     . THR A 1 89  ? -54.604  -27.040  12.709  1.00 26.75  ? 89   THR A O     1 
ATOM   731   C CB    . THR A 1 89  ? -52.051  -28.270  12.193  1.00 29.70  ? 89   THR A CB    1 
ATOM   732   O OG1   . THR A 1 89  ? -51.368  -27.193  12.831  1.00 27.82  ? 89   THR A OG1   1 
ATOM   733   C CG2   . THR A 1 89  ? -51.045  -29.242  11.598  1.00 24.18  ? 89   THR A CG2   1 
ATOM   734   N N     . LYS A 1 90  ? -54.042  -25.449  11.180  1.00 27.10  ? 90   LYS A N     1 
ATOM   735   C CA    . LYS A 1 90  ? -55.064  -24.473  11.545  1.00 36.90  ? 90   LYS A CA    1 
ATOM   736   C C     . LYS A 1 90  ? -55.053  -24.180  13.048  1.00 35.83  ? 90   LYS A C     1 
ATOM   737   O O     . LYS A 1 90  ? -56.106  -24.157  13.658  1.00 37.59  ? 90   LYS A O     1 
ATOM   738   C CB    . LYS A 1 90  ? -56.470  -24.963  11.152  1.00 35.18  ? 90   LYS A CB    1 
ATOM   739   C CG    . LYS A 1 90  ? -56.598  -25.261  9.673   1.00 44.15  ? 90   LYS A CG    1 
ATOM   740   C CD    . LYS A 1 90  ? -58.052  -25.356  9.241   1.00 57.76  ? 90   LYS A CD    1 
ATOM   741   C CE    . LYS A 1 90  ? -58.294  -24.199  8.335   1.00 69.70  ? 90   LYS A CE    1 
ATOM   742   N NZ    . LYS A 1 90  ? -57.198  -24.106  7.351   1.00 74.63  ? 90   LYS A NZ    1 
ATOM   743   N N     . GLY A 1 91  ? -53.869  -24.027  13.654  1.00 34.53  ? 91   GLY A N     1 
ATOM   744   C CA    . GLY A 1 91  ? -53.773  -23.711  15.068  1.00 32.74  ? 91   GLY A CA    1 
ATOM   745   C C     . GLY A 1 91  ? -53.529  -24.916  15.971  1.00 33.73  ? 91   GLY A C     1 
ATOM   746   O O     . GLY A 1 91  ? -53.176  -24.733  17.132  1.00 36.31  ? 91   GLY A O     1 
ATOM   747   N N     . LEU A 1 92  ? -53.670  -26.148  15.462  1.00 27.30  ? 92   LEU A N     1 
ATOM   748   C CA    . LEU A 1 92  ? -53.407  -27.274  16.347  1.00 27.15  ? 92   LEU A CA    1 
ATOM   749   C C     . LEU A 1 92  ? -51.947  -27.315  16.808  1.00 26.38  ? 92   LEU A C     1 
ATOM   750   O O     . LEU A 1 92  ? -51.668  -27.724  17.920  1.00 26.27  ? 92   LEU A O     1 
ATOM   751   C CB    . LEU A 1 92  ? -53.818  -28.581  15.687  1.00 29.68  ? 92   LEU A CB    1 
ATOM   752   C CG    . LEU A 1 92  ? -53.564  -29.820  16.544  1.00 37.39  ? 92   LEU A CG    1 
ATOM   753   C CD1   . LEU A 1 92  ? -54.534  -29.860  17.727  1.00 34.61  ? 92   LEU A CD1   1 
ATOM   754   C CD2   . LEU A 1 92  ? -53.682  -31.085  15.708  1.00 38.00  ? 92   LEU A CD2   1 
ATOM   755   N N     . SER A 1 93  ? -51.003  -26.929  15.943  1.00 27.83  ? 93   SER A N     1 
ATOM   756   C CA    . SER A 1 93  ? -49.586  -27.082  16.260  1.00 29.39  ? 93   SER A CA    1 
ATOM   757   C C     . SER A 1 93  ? -48.776  -26.013  15.539  1.00 34.12  ? 93   SER A C     1 
ATOM   758   O O     . SER A 1 93  ? -49.136  -25.625  14.429  1.00 38.14  ? 93   SER A O     1 
ATOM   759   C CB    . SER A 1 93  ? -49.087  -28.470  15.868  1.00 27.43  ? 93   SER A CB    1 
ATOM   760   O OG    . SER A 1 93  ? -47.677  -28.541  15.970  1.00 27.03  ? 93   SER A OG    1 
ATOM   761   N N     . ASP A 1 94  ? -47.660  -25.578  16.140  1.00 31.30  ? 94   ASP A N     1 
ATOM   762   C CA    . ASP A 1 94  ? -46.746  -24.688  15.433  1.00 30.88  ? 94   ASP A CA    1 
ATOM   763   C C     . ASP A 1 94  ? -45.686  -25.476  14.649  1.00 32.07  ? 94   ASP A C     1 
ATOM   764   O O     . ASP A 1 94  ? -44.865  -24.883  13.936  1.00 26.05  ? 94   ASP A O     1 
ATOM   765   C CB    . ASP A 1 94  ? -46.056  -23.685  16.337  1.00 33.75  ? 94   ASP A CB    1 
ATOM   766   C CG    . ASP A 1 94  ? -45.090  -24.259  17.370  1.00 37.74  ? 94   ASP A CG    1 
ATOM   767   O OD1   . ASP A 1 94  ? -45.016  -25.507  17.479  1.00 41.57  ? 94   ASP A OD1   1 
ATOM   768   O OD2   . ASP A 1 94  ? -44.393  -23.458  18.048  1.00 38.31  ? 94   ASP A OD2   1 
ATOM   769   N N     . PHE A 1 95  ? -45.665  -26.800  14.838  1.00 27.20  ? 95   PHE A N     1 
ATOM   770   C CA    . PHE A 1 95  ? -44.650  -27.634  14.210  1.00 26.65  ? 95   PHE A CA    1 
ATOM   771   C C     . PHE A 1 95  ? -45.214  -28.156  12.875  1.00 27.47  ? 95   PHE A C     1 
ATOM   772   O O     . PHE A 1 95  ? -45.474  -29.348  12.722  1.00 26.30  ? 95   PHE A O     1 
ATOM   773   C CB    . PHE A 1 95  ? -44.305  -28.735  15.214  1.00 20.88  ? 95   PHE A CB    1 
ATOM   774   C CG    . PHE A 1 95  ? -43.006  -29.475  14.930  1.00 27.33  ? 95   PHE A CG    1 
ATOM   775   C CD1   . PHE A 1 95  ? -41.826  -28.774  14.641  1.00 26.15  ? 95   PHE A CD1   1 
ATOM   776   C CD2   . PHE A 1 95  ? -42.959  -30.882  14.960  1.00 26.12  ? 95   PHE A CD2   1 
ATOM   777   C CE1   . PHE A 1 95  ? -40.622  -29.455  14.453  1.00 25.68  ? 95   PHE A CE1   1 
ATOM   778   C CE2   . PHE A 1 95  ? -41.759  -31.568  14.749  1.00 26.39  ? 95   PHE A CE2   1 
ATOM   779   C CZ    . PHE A 1 95  ? -40.602  -30.849  14.482  1.00 28.20  ? 95   PHE A CZ    1 
ATOM   780   N N     . ASP A 1 96  ? -45.483  -27.238  11.941  1.00 24.08  ? 96   ASP A N     1 
ATOM   781   C CA    . ASP A 1 96  ? -46.110  -27.582  10.686  1.00 27.21  ? 96   ASP A CA    1 
ATOM   782   C C     . ASP A 1 96  ? -45.508  -26.704  9.588   1.00 30.89  ? 96   ASP A C     1 
ATOM   783   O O     . ASP A 1 96  ? -44.753  -25.771  9.848   1.00 27.53  ? 96   ASP A O     1 
ATOM   784   C CB    . ASP A 1 96  ? -47.631  -27.557  10.788  1.00 27.75  ? 96   ASP A CB    1 
ATOM   785   C CG    . ASP A 1 96  ? -48.333  -26.195  10.731  1.00 32.28  ? 96   ASP A CG    1 
ATOM   786   O OD1   . ASP A 1 96  ? -47.668  -25.198  10.385  1.00 36.38  ? 96   ASP A OD1   1 
ATOM   787   O OD2   . ASP A 1 96  ? -49.562  -26.122  11.012  1.00 30.33  ? 96   ASP A OD2   1 
ATOM   788   N N     . VAL A 1 97  ? -45.891  -26.995  8.349   1.00 26.37  ? 97   VAL A N     1 
ATOM   789   C CA    . VAL A 1 97  ? -45.232  -26.410  7.207   1.00 26.74  ? 97   VAL A CA    1 
ATOM   790   C C     . VAL A 1 97  ? -45.542  -24.914  7.111   1.00 29.59  ? 97   VAL A C     1 
ATOM   791   O O     . VAL A 1 97  ? -44.751  -24.179  6.528   1.00 31.13  ? 97   VAL A O     1 
ATOM   792   C CB    . VAL A 1 97  ? -45.682  -27.189  5.953   1.00 27.14  ? 97   VAL A CB    1 
ATOM   793   C CG1   . VAL A 1 97  ? -47.169  -27.011  5.696   1.00 24.17  ? 97   VAL A CG1   1 
ATOM   794   C CG2   . VAL A 1 97  ? -44.857  -26.761  4.749   1.00 25.16  ? 97   VAL A CG2   1 
ATOM   795   N N     . MET A 1 98  ? -46.660  -24.460  7.702   1.00 32.99  ? 98   MET A N     1 
ATOM   796   C CA    . MET A 1 98  ? -46.982  -23.036  7.676   1.00 33.41  ? 98   MET A CA    1 
ATOM   797   C C     . MET A 1 98  ? -46.013  -22.233  8.553   1.00 33.02  ? 98   MET A C     1 
ATOM   798   O O     . MET A 1 98  ? -45.883  -21.039  8.361   1.00 34.90  ? 98   MET A O     1 
ATOM   799   C CB    . MET A 1 98  ? -48.437  -22.733  8.062   1.00 29.46  ? 98   MET A CB    1 
ATOM   800   C CG    . MET A 1 98  ? -49.444  -23.443  7.201   1.00 37.54  ? 98   MET A CG    1 
ATOM   801   S SD    . MET A 1 98  ? -49.274  -23.319  5.410   1.00 43.89  ? 98   MET A SD    1 
ATOM   802   C CE    . MET A 1 98  ? -49.567  -21.583  5.037   1.00 42.08  ? 98   MET A CE    1 
ATOM   803   N N     . HIS A 1 99  ? -45.289  -22.888  9.461   1.00 31.48  ? 99   HIS A N     1 
ATOM   804   C CA    . HIS A 1 99  ? -44.317  -22.220  10.308  1.00 29.37  ? 99   HIS A CA    1 
ATOM   805   C C     . HIS A 1 99  ? -42.908  -22.508  9.810   1.00 34.90  ? 99   HIS A C     1 
ATOM   806   O O     . HIS A 1 99  ? -41.930  -22.284  10.536  1.00 35.61  ? 99   HIS A O     1 
ATOM   807   C CB    . HIS A 1 99  ? -44.464  -22.691  11.760  1.00 31.57  ? 99   HIS A CB    1 
ATOM   808   C CG    . HIS A 1 99  ? -45.774  -22.237  12.325  1.00 45.43  ? 99   HIS A CG    1 
ATOM   809   N ND1   . HIS A 1 99  ? -46.970  -22.860  12.008  1.00 45.50  ? 99   HIS A ND1   1 
ATOM   810   C CD2   . HIS A 1 99  ? -46.087  -21.228  13.157  1.00 40.97  ? 99   HIS A CD2   1 
ATOM   811   C CE1   . HIS A 1 99  ? -47.970  -22.235  12.612  1.00 42.26  ? 99   HIS A CE1   1 
ATOM   812   N NE2   . HIS A 1 99  ? -47.455  -21.253  13.322  1.00 47.89  ? 99   HIS A NE2   1 
ATOM   813   N N     . ALA A 1 100 ? -42.804  -23.052  8.582   1.00 30.88  ? 100  ALA A N     1 
ATOM   814   C CA    . ALA A 1 100 ? -41.501  -23.293  7.993   1.00 27.24  ? 100  ALA A CA    1 
ATOM   815   C C     . ALA A 1 100 ? -41.344  -22.284  6.863   1.00 27.11  ? 100  ALA A C     1 
ATOM   816   O O     . ALA A 1 100 ? -42.342  -21.776  6.333   1.00 33.14  ? 100  ALA A O     1 
ATOM   817   C CB    . ALA A 1 100 ? -41.443  -24.714  7.479   1.00 28.03  ? 100  ALA A CB    1 
ATOM   818   N N     . PRO A 1 101 ? -40.106  -21.987  6.407   1.00 26.52  ? 101  PRO A N     1 
ATOM   819   C CA    . PRO A 1 101 ? -39.939  -21.139  5.229   1.00 28.28  ? 101  PRO A CA    1 
ATOM   820   C C     . PRO A 1 101 ? -40.799  -21.542  4.030   1.00 33.07  ? 101  PRO A C     1 
ATOM   821   O O     . PRO A 1 101 ? -41.184  -20.683  3.253   1.00 35.60  ? 101  PRO A O     1 
ATOM   822   C CB    . PRO A 1 101 ? -38.435  -21.100  4.969   1.00 26.63  ? 101  PRO A CB    1 
ATOM   823   C CG    . PRO A 1 101 ? -37.861  -22.169  5.890   1.00 28.27  ? 101  PRO A CG    1 
ATOM   824   C CD    . PRO A 1 101 ? -38.834  -22.434  7.007   1.00 26.44  ? 101  PRO A CD    1 
ATOM   825   N N     . ALA A 1 102 ? -41.132  -22.833  3.872   1.00 31.99  ? 102  ALA A N     1 
ATOM   826   C CA    . ALA A 1 102 ? -41.951  -23.232  2.737   1.00 32.96  ? 102  ALA A CA    1 
ATOM   827   C C     . ALA A 1 102 ? -43.247  -22.421  2.657   1.00 34.34  ? 102  ALA A C     1 
ATOM   828   O O     . ALA A 1 102 ? -43.651  -22.021  1.567   1.00 31.18  ? 102  ALA A O     1 
ATOM   829   C CB    . ALA A 1 102 ? -42.230  -24.715  2.793   1.00 30.94  ? 102  ALA A CB    1 
ATOM   830   N N     . ARG A 1 103 ? -43.989  -22.304  3.748   1.00 36.83  ? 103  ARG A N     1 
ATOM   831   C CA    . ARG A 1 103 ? -45.260  -21.557  3.821   1.00 42.33  ? 103  ARG A CA    1 
ATOM   832   C C     . ARG A 1 103 ? -46.302  -21.978  2.801   1.00 39.42  ? 103  ARG A C     1 
ATOM   833   O O     . ARG A 1 103 ? -47.009  -21.157  2.291   1.00 40.29  ? 103  ARG A O     1 
ATOM   834   C CB    . ARG A 1 103 ? -45.091  -20.037  3.693   1.00 45.61  ? 103  ARG A CB    1 
ATOM   835   C CG    . ARG A 1 103 ? -44.002  -19.367  4.467   1.00 57.70  ? 103  ARG A CG    1 
ATOM   836   C CD    . ARG A 1 103 ? -44.479  -18.742  5.749   1.00 79.60  ? 103  ARG A CD    1 
ATOM   837   N NE    . ARG A 1 103 ? -43.476  -19.009  6.770   1.00 117.10 ? 103  ARG A NE    1 
ATOM   838   C CZ    . ARG A 1 103 ? -43.578  -18.707  8.054   1.00 110.46 ? 103  ARG A CZ    1 
ATOM   839   N NH1   . ARG A 1 103 ? -44.653  -18.100  8.528   1.00 106.06 ? 103  ARG A NH1   1 
ATOM   840   N NH2   . ARG A 1 103 ? -42.584  -19.013  8.859   1.00 92.28  ? 103  ARG A NH2   1 
ATOM   841   N N     . ARG A 1 104 ? -46.382  -23.253  2.502   1.00 36.73  ? 104  ARG A N     1 
ATOM   842   C CA    . ARG A 1 104 ? -47.326  -23.760  1.543   1.00 33.42  ? 104  ARG A CA    1 
ATOM   843   C C     . ARG A 1 104 ? -47.973  -24.958  2.143   1.00 33.58  ? 104  ARG A C     1 
ATOM   844   O O     . ARG A 1 104 ? -47.332  -25.697  2.803   1.00 33.73  ? 104  ARG A O     1 
ATOM   845   C CB    . ARG A 1 104 ? -46.597  -24.226  0.306   1.00 30.78  ? 104  ARG A CB    1 
ATOM   846   C CG    . ARG A 1 104 ? -46.060  -23.166  -0.600  1.00 33.37  ? 104  ARG A CG    1 
ATOM   847   C CD    . ARG A 1 104 ? -44.775  -23.613  -1.230  1.00 41.93  ? 104  ARG A CD    1 
ATOM   848   N NE    . ARG A 1 104 ? -44.913  -24.779  -2.074  1.00 44.28  ? 104  ARG A NE    1 
ATOM   849   C CZ    . ARG A 1 104 ? -43.901  -25.468  -2.562  1.00 37.95  ? 104  ARG A CZ    1 
ATOM   850   N NH1   . ARG A 1 104 ? -44.110  -26.496  -3.311  1.00 32.52  ? 104  ARG A NH1   1 
ATOM   851   N NH2   . ARG A 1 104 ? -42.686  -25.108  -2.311  1.00 39.13  ? 104  ARG A NH2   1 
ATOM   852   N N     . ASP A 1 105 ? -49.247  -25.163  1.905   1.00 29.43  ? 105  ASP A N     1 
ATOM   853   C CA    . ASP A 1 105 ? -49.860  -26.358  2.389   1.00 27.59  ? 105  ASP A CA    1 
ATOM   854   C C     . ASP A 1 105 ? -49.555  -27.374  1.290   1.00 29.74  ? 105  ASP A C     1 
ATOM   855   O O     . ASP A 1 105 ? -50.064  -27.314  0.220   1.00 29.49  ? 105  ASP A O     1 
ATOM   856   C CB    . ASP A 1 105 ? -51.335  -26.139  2.584   1.00 22.67  ? 105  ASP A CB    1 
ATOM   857   C CG    . ASP A 1 105 ? -52.011  -27.293  3.199   1.00 30.75  ? 105  ASP A CG    1 
ATOM   858   O OD1   . ASP A 1 105 ? -51.639  -28.407  2.960   1.00 32.13  ? 105  ASP A OD1   1 
ATOM   859   O OD2   . ASP A 1 105 ? -52.940  -27.099  3.938   1.00 32.64  ? 105  ASP A OD2   1 
ATOM   860   N N     . LEU A 1 106 ? -48.622  -28.251  1.592   1.00 26.36  ? 106  LEU A N     1 
ATOM   861   C CA    . LEU A 1 106 ? -48.148  -29.276  0.698   1.00 23.82  ? 106  LEU A CA    1 
ATOM   862   C C     . LEU A 1 106 ? -49.180  -30.322  0.399   1.00 27.02  ? 106  LEU A C     1 
ATOM   863   O O     . LEU A 1 106 ? -49.168  -30.865  -0.653  1.00 28.72  ? 106  LEU A O     1 
ATOM   864   C CB    . LEU A 1 106 ? -46.820  -29.837  1.139   1.00 21.93  ? 106  LEU A CB    1 
ATOM   865   C CG    . LEU A 1 106 ? -45.782  -28.797  1.475   1.00 24.22  ? 106  LEU A CG    1 
ATOM   866   C CD1   . LEU A 1 106 ? -44.735  -29.396  2.355   1.00 26.81  ? 106  LEU A CD1   1 
ATOM   867   C CD2   . LEU A 1 106 ? -45.161  -28.145  0.274   1.00 23.48  ? 106  LEU A CD2   1 
ATOM   868   N N     . ILE A 1 107 ? -49.998  -30.661  1.386   1.00 25.43  ? 107  ILE A N     1 
ATOM   869   C CA    . ILE A 1 107 ? -51.102  -31.578  1.186   1.00 26.34  ? 107  ILE A CA    1 
ATOM   870   C C     . ILE A 1 107 ? -52.106  -31.005  0.184   1.00 29.25  ? 107  ILE A C     1 
ATOM   871   O O     . ILE A 1 107 ? -52.644  -31.766  -0.627  1.00 27.35  ? 107  ILE A O     1 
ATOM   872   C CB    . ILE A 1 107 ? -51.732  -32.022  2.516   1.00 25.18  ? 107  ILE A CB    1 
ATOM   873   C CG1   . ILE A 1 107 ? -50.703  -32.696  3.457   1.00 25.55  ? 107  ILE A CG1   1 
ATOM   874   C CG2   . ILE A 1 107 ? -52.986  -32.872  2.323   1.00 26.61  ? 107  ILE A CG2   1 
ATOM   875   C CD1   . ILE A 1 107 ? -49.657  -33.563  2.788   1.00 25.02  ? 107  ILE A CD1   1 
ATOM   876   N N     . ALA A 1 108 ? -52.339  -29.680  0.203   1.00 28.07  ? 108  ALA A N     1 
ATOM   877   C CA    . ALA A 1 108 ? -53.284  -29.090  -0.744  1.00 30.13  ? 108  ALA A CA    1 
ATOM   878   C C     . ALA A 1 108 ? -52.717  -29.222  -2.151  1.00 25.44  ? 108  ALA A C     1 
ATOM   879   O O     . ALA A 1 108 ? -53.451  -29.581  -3.070  1.00 27.75  ? 108  ALA A O     1 
ATOM   880   C CB    . ALA A 1 108 ? -53.652  -27.634  -0.421  1.00 25.95  ? 108  ALA A CB    1 
ATOM   881   N N     . GLU A 1 109 ? -51.415  -28.958  -2.309  1.00 23.21  ? 109  GLU A N     1 
ATOM   882   C CA    . GLU A 1 109 ? -50.783  -29.093  -3.620  1.00 25.94  ? 109  GLU A CA    1 
ATOM   883   C C     . GLU A 1 109 ? -50.876  -30.550  -4.089  1.00 26.55  ? 109  GLU A C     1 
ATOM   884   O O     . GLU A 1 109 ? -51.194  -30.800  -5.248  1.00 26.34  ? 109  GLU A O     1 
ATOM   885   C CB    . GLU A 1 109 ? -49.339  -28.621  -3.585  1.00 27.02  ? 109  GLU A CB    1 
ATOM   886   C CG    . GLU A 1 109 ? -49.201  -27.142  -3.242  1.00 29.86  ? 109  GLU A CG    1 
ATOM   887   C CD    . GLU A 1 109 ? -47.726  -26.726  -3.121  1.00 35.89  ? 109  GLU A CD    1 
ATOM   888   O OE1   . GLU A 1 109 ? -46.840  -27.568  -3.369  1.00 37.79  ? 109  GLU A OE1   1 
ATOM   889   O OE2   . GLU A 1 109 ? -47.416  -25.555  -2.813  1.00 42.48  ? 109  GLU A OE2   1 
ATOM   890   N N     . PHE A 1 110 ? -50.680  -31.500  -3.165  1.00 23.63  ? 110  PHE A N     1 
ATOM   891   C CA    . PHE A 1 110 ? -50.668  -32.915  -3.469  1.00 26.87  ? 110  PHE A CA    1 
ATOM   892   C C     . PHE A 1 110 ? -52.044  -33.374  -3.939  1.00 26.90  ? 110  PHE A C     1 
ATOM   893   O O     . PHE A 1 110 ? -52.153  -34.075  -4.934  1.00 29.77  ? 110  PHE A O     1 
ATOM   894   C CB    . PHE A 1 110 ? -50.198  -33.641  -2.206  1.00 27.46  ? 110  PHE A CB    1 
ATOM   895   C CG    . PHE A 1 110 ? -50.434  -35.141  -2.206  1.00 30.29  ? 110  PHE A CG    1 
ATOM   896   C CD1   . PHE A 1 110 ? -49.709  -35.976  -3.075  1.00 27.70  ? 110  PHE A CD1   1 
ATOM   897   C CD2   . PHE A 1 110 ? -51.337  -35.723  -1.319  1.00 23.20  ? 110  PHE A CD2   1 
ATOM   898   C CE1   . PHE A 1 110 ? -49.906  -37.360  -3.058  1.00 25.84  ? 110  PHE A CE1   1 
ATOM   899   C CE2   . PHE A 1 110 ? -51.538  -37.109  -1.311  1.00 24.63  ? 110  PHE A CE2   1 
ATOM   900   C CZ    . PHE A 1 110 ? -50.824  -37.932  -2.172  1.00 24.41  ? 110  PHE A CZ    1 
ATOM   901   N N     . VAL A 1 111 ? -53.091  -32.978  -3.219  1.00 27.49  ? 111  VAL A N     1 
ATOM   902   C CA    . VAL A 1 111 ? -54.446  -33.410  -3.542  1.00 27.62  ? 111  VAL A CA    1 
ATOM   903   C C     . VAL A 1 111 ? -54.867  -32.880  -4.919  1.00 28.22  ? 111  VAL A C     1 
ATOM   904   O O     . VAL A 1 111 ? -55.469  -33.597  -5.708  1.00 28.60  ? 111  VAL A O     1 
ATOM   905   C CB    . VAL A 1 111 ? -55.380  -32.928  -2.407  1.00 28.24  ? 111  VAL A CB    1 
ATOM   906   C CG1   . VAL A 1 111 ? -56.803  -32.704  -2.872  1.00 26.08  ? 111  VAL A CG1   1 
ATOM   907   C CG2   . VAL A 1 111 ? -55.320  -33.843  -1.186  1.00 26.00  ? 111  VAL A CG2   1 
ATOM   908   N N     . ALA A 1 112 ? -54.543  -31.624  -5.224  1.00 26.11  ? 112  ALA A N     1 
ATOM   909   C CA    . ALA A 1 112 ? -54.916  -31.030  -6.504  1.00 28.03  ? 112  ALA A CA    1 
ATOM   910   C C     . ALA A 1 112 ? -54.164  -31.761  -7.627  1.00 27.83  ? 112  ALA A C     1 
ATOM   911   O O     . ALA A 1 112 ? -54.761  -32.111  -8.646  1.00 28.45  ? 112  ALA A O     1 
ATOM   912   C CB    . ALA A 1 112 ? -54.633  -29.509  -6.513  1.00 20.42  ? 112  ALA A CB    1 
ATOM   913   N N     . ALA A 1 113 ? -52.868  -32.047  -7.418  1.00 23.63  ? 113  ALA A N     1 
ATOM   914   C CA    . ALA A 1 113 ? -52.068  -32.725  -8.431  1.00 23.20  ? 113  ALA A CA    1 
ATOM   915   C C     . ALA A 1 113 ? -52.630  -34.133  -8.667  1.00 25.79  ? 113  ALA A C     1 
ATOM   916   O O     . ALA A 1 113 ? -52.740  -34.542  -9.807  1.00 26.23  ? 113  ALA A O     1 
ATOM   917   C CB    . ALA A 1 113 ? -50.607  -32.714  -8.036  1.00 19.97  ? 113  ALA A CB    1 
ATOM   918   N N     . CYS A 1 114 ? -53.034  -34.849  -7.600  1.00 23.17  ? 114  CYS A N     1 
ATOM   919   C CA    . CYS A 1 114 ? -53.595  -36.184  -7.763  1.00 22.90  ? 114  CYS A CA    1 
ATOM   920   C C     . CYS A 1 114 ? -54.880  -36.131  -8.587  1.00 26.33  ? 114  CYS A C     1 
ATOM   921   O O     . CYS A 1 114 ? -55.076  -36.969  -9.463  1.00 25.28  ? 114  CYS A O     1 
ATOM   922   C CB    . CYS A 1 114 ? -53.910  -36.881  -6.448  1.00 21.07  ? 114  CYS A CB    1 
ATOM   923   S SG    . CYS A 1 114 ? -52.418  -37.377  -5.532  1.00 25.28  ? 114  CYS A SG    1 
ATOM   924   N N     . ARG A 1 115 ? -55.737  -35.142  -8.308  1.00 26.85  ? 115  ARG A N     1 
ATOM   925   C CA    . ARG A 1 115 ? -57.020  -35.069  -8.980  1.00 31.05  ? 115  ARG A CA    1 
ATOM   926   C C     . ARG A 1 115 ? -56.825  -34.821  -10.466 1.00 28.45  ? 115  ARG A C     1 
ATOM   927   O O     . ARG A 1 115 ? -57.538  -35.396  -11.261 1.00 29.76  ? 115  ARG A O     1 
ATOM   928   C CB    . ARG A 1 115 ? -57.982  -34.015  -8.425  1.00 33.64  ? 115  ARG A CB    1 
ATOM   929   C CG    . ARG A 1 115 ? -58.625  -34.654  -7.208  1.00 46.50  ? 115  ARG A CG    1 
ATOM   930   C CD    . ARG A 1 115 ? -59.207  -33.581  -6.343  1.00 46.73  ? 115  ARG A CD    1 
ATOM   931   N NE    . ARG A 1 115 ? -59.504  -34.204  -5.050  1.00 47.79  ? 115  ARG A NE    1 
ATOM   932   C CZ    . ARG A 1 115 ? -59.815  -33.460  -3.993  1.00 47.04  ? 115  ARG A CZ    1 
ATOM   933   N NH1   . ARG A 1 115 ? -59.741  -32.139  -4.066  1.00 36.17  ? 115  ARG A NH1   1 
ATOM   934   N NH2   . ARG A 1 115 ? -60.155  -34.041  -2.857  1.00 46.62  ? 115  ARG A NH2   1 
ATOM   935   N N     . GLU A 1 116 ? -55.872  -33.976  -10.830 1.00 28.72  ? 116  GLU A N     1 
ATOM   936   C CA    . GLU A 1 116 ? -55.625  -33.686  -12.227 1.00 31.64  ? 116  GLU A CA    1 
ATOM   937   C C     . GLU A 1 116 ? -55.173  -34.945  -12.983 1.00 31.06  ? 116  GLU A C     1 
ATOM   938   O O     . GLU A 1 116 ? -55.399  -35.030  -14.190 1.00 30.72  ? 116  GLU A O     1 
ATOM   939   C CB    . GLU A 1 116 ? -54.571  -32.596  -12.428 1.00 35.19  ? 116  GLU A CB    1 
ATOM   940   C CG    . GLU A 1 116 ? -55.140  -31.185  -12.328 1.00 56.78  ? 116  GLU A CG    1 
ATOM   941   C CD    . GLU A 1 116 ? -54.034  -30.157  -12.140 1.00 75.35  ? 116  GLU A CD    1 
ATOM   942   O OE1   . GLU A 1 116 ? -54.097  -29.116  -12.828 1.00 84.71  ? 116  GLU A OE1   1 
ATOM   943   O OE2   . GLU A 1 116 ? -53.088  -30.369  -11.351 1.00 87.03  ? 116  GLU A OE2   1 
ATOM   944   N N     . GLU A 1 117 ? -54.575  -35.924  -12.287 1.00 28.70  ? 117  GLU A N     1 
ATOM   945   C CA    . GLU A 1 117 ? -54.038  -37.100  -12.963 1.00 26.61  ? 117  GLU A CA    1 
ATOM   946   C C     . GLU A 1 117 ? -54.953  -38.299  -12.740 1.00 27.60  ? 117  GLU A C     1 
ATOM   947   O O     . GLU A 1 117 ? -54.598  -39.415  -13.101 1.00 28.22  ? 117  GLU A O     1 
ATOM   948   C CB    . GLU A 1 117 ? -52.640  -37.443  -12.443 1.00 27.82  ? 117  GLU A CB    1 
ATOM   949   C CG    . GLU A 1 117 ? -51.564  -36.434  -12.785 1.00 29.46  ? 117  GLU A CG    1 
ATOM   950   C CD    . GLU A 1 117 ? -51.640  -36.020  -14.223 1.00 36.10  ? 117  GLU A CD    1 
ATOM   951   O OE1   . GLU A 1 117 ? -51.442  -36.913  -15.059 1.00 42.85  ? 117  GLU A OE1   1 
ATOM   952   O OE2   . GLU A 1 117 ? -51.974  -34.859  -14.465 1.00 38.46  ? 117  GLU A OE2   1 
ATOM   953   N N     . ASP A 1 118 ? -56.124  -38.073  -12.126 1.00 28.60  ? 118  ASP A N     1 
ATOM   954   C CA    . ASP A 1 118 ? -57.057  -39.138  -11.810 1.00 30.53  ? 118  ASP A CA    1 
ATOM   955   C C     . ASP A 1 118 ? -56.441  -40.161  -10.853 1.00 26.86  ? 118  ASP A C     1 
ATOM   956   O O     . ASP A 1 118 ? -56.725  -41.351  -10.932 1.00 29.23  ? 118  ASP A O     1 
ATOM   957   C CB    . ASP A 1 118 ? -57.755  -39.631  -13.072 1.00 42.17  ? 118  ASP A CB    1 
ATOM   958   C CG    . ASP A 1 118 ? -59.021  -40.457  -12.823 1.00 72.26  ? 118  ASP A CG    1 
ATOM   959   O OD1   . ASP A 1 118 ? -59.842  -40.034  -11.965 1.00 80.82  ? 118  ASP A OD1   1 
ATOM   960   O OD2   . ASP A 1 118 ? -59.208  -41.532  -13.474 1.00 78.90  ? 118  ASP A OD2   1 
ATOM   961   N N     . LEU A 1 119 ? -55.628  -39.716  -9.895  1.00 27.10  ? 119  LEU A N     1 
ATOM   962   C CA    . LEU A 1 119 ? -55.098  -40.605  -8.866  1.00 23.94  ? 119  LEU A CA    1 
ATOM   963   C C     . LEU A 1 119 ? -55.840  -40.352  -7.556  1.00 24.23  ? 119  LEU A C     1 
ATOM   964   O O     . LEU A 1 119 ? -56.188  -39.209  -7.257  1.00 28.35  ? 119  LEU A O     1 
ATOM   965   C CB    . LEU A 1 119 ? -53.620  -40.261  -8.699  1.00 25.54  ? 119  LEU A CB    1 
ATOM   966   C CG    . LEU A 1 119 ? -52.749  -40.379  -9.952  1.00 25.37  ? 119  LEU A CG    1 
ATOM   967   C CD1   . LEU A 1 119 ? -51.340  -39.918  -9.658  1.00 24.52  ? 119  LEU A CD1   1 
ATOM   968   C CD2   . LEU A 1 119 ? -52.754  -41.784  -10.485 1.00 22.67  ? 119  LEU A CD2   1 
ATOM   969   N N     . LEU A 1 120 ? -56.023  -41.392  -6.745  1.00 22.23  ? 120  LEU A N     1 
ATOM   970   C CA    . LEU A 1 120 ? -56.556  -41.182  -5.409  1.00 22.14  ? 120  LEU A CA    1 
ATOM   971   C C     . LEU A 1 120 ? -55.455  -40.708  -4.448  1.00 24.36  ? 120  LEU A C     1 
ATOM   972   O O     . LEU A 1 120 ? -54.426  -41.363  -4.335  1.00 21.88  ? 120  LEU A O     1 
ATOM   973   C CB    . LEU A 1 120 ? -57.278  -42.413  -4.874  1.00 19.28  ? 120  LEU A CB    1 
ATOM   974   C CG    . LEU A 1 120 ? -58.533  -42.832  -5.636  1.00 23.83  ? 120  LEU A CG    1 
ATOM   975   C CD1   . LEU A 1 120 ? -59.155  -43.976  -4.853  1.00 22.73  ? 120  LEU A CD1   1 
ATOM   976   C CD2   . LEU A 1 120 ? -59.538  -41.682  -5.791  1.00 23.52  ? 120  LEU A CD2   1 
ATOM   977   N N     . PRO A 1 121 ? -55.644  -39.574  -3.709  1.00 21.26  ? 121  PRO A N     1 
ATOM   978   C CA    . PRO A 1 121 ? -54.701  -39.160  -2.674  1.00 20.62  ? 121  PRO A CA    1 
ATOM   979   C C     . PRO A 1 121 ? -54.967  -39.863  -1.345  1.00 22.72  ? 121  PRO A C     1 
ATOM   980   O O     . PRO A 1 121 ? -56.103  -39.920  -0.876  1.00 25.72  ? 121  PRO A O     1 
ATOM   981   C CB    . PRO A 1 121 ? -54.912  -37.657  -2.563  1.00 20.91  ? 121  PRO A CB    1 
ATOM   982   C CG    . PRO A 1 121 ? -56.426  -37.570  -2.837  1.00 23.11  ? 121  PRO A CG    1 
ATOM   983   C CD    . PRO A 1 121 ? -56.762  -38.630  -3.867  1.00 19.66  ? 121  PRO A CD    1 
ATOM   984   N N     . PHE A 1 122 ? -53.914  -40.460  -0.775  1.00 21.62  ? 122  PHE A N     1 
ATOM   985   C CA    . PHE A 1 122 ? -54.032  -41.123  0.506   1.00 22.68  ? 122  PHE A CA    1 
ATOM   986   C C     . PHE A 1 122 ? -53.101  -40.423  1.489   1.00 20.61  ? 122  PHE A C     1 
ATOM   987   O O     . PHE A 1 122 ? -52.010  -39.990  1.104   1.00 21.76  ? 122  PHE A O     1 
ATOM   988   C CB    . PHE A 1 122 ? -53.627  -42.597  0.467   1.00 19.46  ? 122  PHE A CB    1 
ATOM   989   C CG    . PHE A 1 122 ? -54.666  -43.588  -0.010  1.00 19.04  ? 122  PHE A CG    1 
ATOM   990   C CD1   . PHE A 1 122 ? -55.327  -43.416  -1.227  1.00 18.77  ? 122  PHE A CD1   1 
ATOM   991   C CD2   . PHE A 1 122 ? -54.991  -44.689  0.779   1.00 20.66  ? 122  PHE A CD2   1 
ATOM   992   C CE1   . PHE A 1 122 ? -56.275  -44.345  -1.654  1.00 19.57  ? 122  PHE A CE1   1 
ATOM   993   C CE2   . PHE A 1 122 ? -55.952  -45.610  0.352   1.00 21.38  ? 122  PHE A CE2   1 
ATOM   994   C CZ    . PHE A 1 122 ? -56.588  -45.438  -0.876  1.00 18.90  ? 122  PHE A CZ    1 
ATOM   995   N N     . PHE A 1 123 ? -53.537  -40.356  2.750   1.00 19.71  ? 123  PHE A N     1 
ATOM   996   C CA    . PHE A 1 123 ? -52.773  -39.647  3.766   1.00 21.39  ? 123  PHE A CA    1 
ATOM   997   C C     . PHE A 1 123 ? -52.214  -40.644  4.772   1.00 21.82  ? 123  PHE A C     1 
ATOM   998   O O     . PHE A 1 123 ? -52.973  -41.296  5.472   1.00 26.75  ? 123  PHE A O     1 
ATOM   999   C CB    . PHE A 1 123 ? -53.693  -38.674  4.491   1.00 19.05  ? 123  PHE A CB    1 
ATOM   1000  C CG    . PHE A 1 123 ? -54.288  -37.570  3.631   1.00 21.46  ? 123  PHE A CG    1 
ATOM   1001  C CD1   . PHE A 1 123 ? -53.605  -37.077  2.512   1.00 20.63  ? 123  PHE A CD1   1 
ATOM   1002  C CD2   . PHE A 1 123 ? -55.509  -36.985  3.972   1.00 20.49  ? 123  PHE A CD2   1 
ATOM   1003  C CE1   . PHE A 1 123 ? -54.138  -36.062  1.721   1.00 23.02  ? 123  PHE A CE1   1 
ATOM   1004  C CE2   . PHE A 1 123 ? -56.040  -35.950  3.202   1.00 21.49  ? 123  PHE A CE2   1 
ATOM   1005  C CZ    . PHE A 1 123 ? -55.358  -35.493  2.080   1.00 22.75  ? 123  PHE A CZ    1 
ATOM   1006  N N     . TYR A 1 124 ? -50.890  -40.751  4.840   1.00 19.12  ? 124  TYR A N     1 
ATOM   1007  C CA    . TYR A 1 124 ? -50.276  -41.537  5.896   1.00 19.96  ? 124  TYR A CA    1 
ATOM   1008  C C     . TYR A 1 124 ? -50.245  -40.658  7.149   1.00 22.51  ? 124  TYR A C     1 
ATOM   1009  O O     . TYR A 1 124 ? -49.912  -39.457  7.063   1.00 22.88  ? 124  TYR A O     1 
ATOM   1010  C CB    . TYR A 1 124 ? -48.855  -41.936  5.452   1.00 21.07  ? 124  TYR A CB    1 
ATOM   1011  C CG    . TYR A 1 124 ? -47.954  -42.453  6.570   1.00 21.24  ? 124  TYR A CG    1 
ATOM   1012  C CD1   . TYR A 1 124 ? -47.460  -41.583  7.553   1.00 23.35  ? 124  TYR A CD1   1 
ATOM   1013  C CD2   . TYR A 1 124 ? -47.599  -43.800  6.672   1.00 22.46  ? 124  TYR A CD2   1 
ATOM   1014  C CE1   . TYR A 1 124 ? -46.649  -42.038  8.582   1.00 23.05  ? 124  TYR A CE1   1 
ATOM   1015  C CE2   . TYR A 1 124 ? -46.789  -44.283  7.708   1.00 20.70  ? 124  TYR A CE2   1 
ATOM   1016  C CZ    . TYR A 1 124 ? -46.322  -43.392  8.661   1.00 25.13  ? 124  TYR A CZ    1 
ATOM   1017  O OH    . TYR A 1 124 ? -45.521  -43.818  9.682   1.00 27.41  ? 124  TYR A OH    1 
ATOM   1018  N N     . MET A 1 125 ? -50.560  -41.265  8.303   1.00 21.14  ? 125  MET A N     1 
ATOM   1019  C CA    . MET A 1 125 ? -50.516  -40.540  9.567   1.00 22.32  ? 125  MET A CA    1 
ATOM   1020  C C     . MET A 1 125 ? -49.896  -41.451  10.627  1.00 21.80  ? 125  MET A C     1 
ATOM   1021  O O     . MET A 1 125 ? -50.379  -42.573  10.844  1.00 21.08  ? 125  MET A O     1 
ATOM   1022  C CB    . MET A 1 125 ? -51.928  -40.107  9.997   1.00 26.29  ? 125  MET A CB    1 
ATOM   1023  C CG    . MET A 1 125 ? -52.036  -39.645  11.461  1.00 24.05  ? 125  MET A CG    1 
ATOM   1024  S SD    . MET A 1 125 ? -51.165  -38.099  11.824  1.00 26.59  ? 125  MET A SD    1 
ATOM   1025  C CE    . MET A 1 125 ? -52.057  -36.919  10.784  1.00 19.46  ? 125  MET A CE    1 
ATOM   1026  N N     . ALA A 1 126 ? -48.797  -40.997  11.253  1.00 20.85  ? 126  ALA A N     1 
ATOM   1027  C CA    . ALA A 1 126 ? -48.192  -41.785  12.330  1.00 23.93  ? 126  ALA A CA    1 
ATOM   1028  C C     . ALA A 1 126 ? -48.960  -41.557  13.637  1.00 27.19  ? 126  ALA A C     1 
ATOM   1029  O O     . ALA A 1 126 ? -49.209  -40.409  14.031  1.00 30.54  ? 126  ALA A O     1 
ATOM   1030  C CB    . ALA A 1 126 ? -46.739  -41.420  12.508  1.00 23.22  ? 126  ALA A CB    1 
ATOM   1031  N N     . THR A 1 127 ? -49.323  -42.639  14.328  1.00 24.17  ? 127  THR A N     1 
ATOM   1032  C CA    . THR A 1 127 ? -50.054  -42.468  15.570  1.00 28.52  ? 127  THR A CA    1 
ATOM   1033  C C     . THR A 1 127 ? -49.096  -42.494  16.769  1.00 29.32  ? 127  THR A C     1 
ATOM   1034  O O     . THR A 1 127 ? -49.445  -42.037  17.861  1.00 31.24  ? 127  THR A O     1 
ATOM   1035  C CB    . THR A 1 127 ? -51.174  -43.499  15.691  1.00 28.18  ? 127  THR A CB    1 
ATOM   1036  O OG1   . THR A 1 127 ? -50.487  -44.743  15.791  1.00 30.01  ? 127  THR A OG1   1 
ATOM   1037  C CG2   . THR A 1 127 ? -52.108  -43.473  14.500  1.00 26.11  ? 127  THR A CG2   1 
ATOM   1038  N N     . TYR A 1 128 ? -47.887  -43.019  16.565  1.00 27.38  ? 128  TYR A N     1 
ATOM   1039  C CA    . TYR A 1 128 ? -46.843  -42.906  17.579  1.00 29.42  ? 128  TYR A CA    1 
ATOM   1040  C C     . TYR A 1 128 ? -46.036  -41.636  17.286  1.00 31.63  ? 128  TYR A C     1 
ATOM   1041  O O     . TYR A 1 128 ? -45.451  -41.520  16.194  1.00 32.53  ? 128  TYR A O     1 
ATOM   1042  C CB    . TYR A 1 128 ? -45.987  -44.162  17.398  1.00 25.83  ? 128  TYR A CB    1 
ATOM   1043  C CG    . TYR A 1 128 ? -44.699  -44.278  18.198  1.00 29.98  ? 128  TYR A CG    1 
ATOM   1044  C CD1   . TYR A 1 128 ? -44.544  -43.672  19.453  1.00 31.48  ? 128  TYR A CD1   1 
ATOM   1045  C CD2   . TYR A 1 128 ? -43.627  -45.027  17.708  1.00 32.53  ? 128  TYR A CD2   1 
ATOM   1046  C CE1   . TYR A 1 128 ? -43.375  -43.817  20.192  1.00 26.64  ? 128  TYR A CE1   1 
ATOM   1047  C CE2   . TYR A 1 128 ? -42.455  -45.196  18.439  1.00 30.30  ? 128  TYR A CE2   1 
ATOM   1048  C CZ    . TYR A 1 128 ? -42.331  -44.580  19.681  1.00 32.31  ? 128  TYR A CZ    1 
ATOM   1049  O OH    . TYR A 1 128 ? -41.191  -44.695  20.420  1.00 32.96  ? 128  TYR A OH    1 
ATOM   1050  N N     . ASP A 1 129 ? -46.044  -40.691  18.241  1.00 28.63  ? 129  ASP A N     1 
ATOM   1051  C CA    . ASP A 1 129 ? -45.605  -39.327  17.969  1.00 26.55  ? 129  ASP A CA    1 
ATOM   1052  C C     . ASP A 1 129 ? -44.494  -38.950  18.947  1.00 25.45  ? 129  ASP A C     1 
ATOM   1053  O O     . ASP A 1 129 ? -44.675  -39.105  20.153  1.00 35.20  ? 129  ASP A O     1 
ATOM   1054  C CB    . ASP A 1 129 ? -46.793  -38.391  18.029  1.00 27.02  ? 129  ASP A CB    1 
ATOM   1055  C CG    . ASP A 1 129 ? -46.545  -36.939  17.650  1.00 32.83  ? 129  ASP A CG    1 
ATOM   1056  O OD1   . ASP A 1 129 ? -45.568  -36.338  18.196  1.00 32.98  ? 129  ASP A OD1   1 
ATOM   1057  O OD2   . ASP A 1 129 ? -47.356  -36.422  16.825  1.00 30.70  ? 129  ASP A OD2   1 
ATOM   1058  N N     . TRP A 1 130 ? -43.345  -38.479  18.439  1.00 26.49  ? 130  TRP A N     1 
ATOM   1059  C CA    . TRP A 1 130 ? -42.190  -38.162  19.281  1.00 29.45  ? 130  TRP A CA    1 
ATOM   1060  C C     . TRP A 1 130 ? -42.160  -36.669  19.604  1.00 30.89  ? 130  TRP A C     1 
ATOM   1061  O O     . TRP A 1 130 ? -41.274  -36.233  20.329  1.00 30.33  ? 130  TRP A O     1 
ATOM   1062  C CB    . TRP A 1 130 ? -40.861  -38.513  18.585  1.00 31.57  ? 130  TRP A CB    1 
ATOM   1063  C CG    . TRP A 1 130 ? -40.723  -39.949  18.157  1.00 31.89  ? 130  TRP A CG    1 
ATOM   1064  C CD1   . TRP A 1 130 ? -41.350  -41.019  18.718  1.00 31.18  ? 130  TRP A CD1   1 
ATOM   1065  C CD2   . TRP A 1 130 ? -39.933  -40.467  17.062  1.00 27.47  ? 130  TRP A CD2   1 
ATOM   1066  N NE1   . TRP A 1 130 ? -40.997  -42.177  18.064  1.00 33.53  ? 130  TRP A NE1   1 
ATOM   1067  C CE2   . TRP A 1 130 ? -40.129  -41.872  17.042  1.00 31.62  ? 130  TRP A CE2   1 
ATOM   1068  C CE3   . TRP A 1 130 ? -39.094  -39.897  16.098  1.00 27.30  ? 130  TRP A CE3   1 
ATOM   1069  C CZ2   . TRP A 1 130 ? -39.518  -42.705  16.098  1.00 26.65  ? 130  TRP A CZ2   1 
ATOM   1070  C CZ3   . TRP A 1 130 ? -38.488  -40.718  15.160  1.00 25.16  ? 130  TRP A CZ3   1 
ATOM   1071  C CH2   . TRP A 1 130 ? -38.707  -42.098  15.160  1.00 25.28  ? 130  TRP A CH2   1 
ATOM   1072  N N     . HIS A 1 131 ? -43.049  -35.872  18.991  1.00 29.13  ? 131  HIS A N     1 
ATOM   1073  C CA    . HIS A 1 131 ? -42.962  -34.432  19.154  1.00 30.13  ? 131  HIS A CA    1 
ATOM   1074  C C     . HIS A 1 131 ? -43.728  -33.940  20.384  1.00 30.16  ? 131  HIS A C     1 
ATOM   1075  O O     . HIS A 1 131 ? -43.163  -33.226  21.199  1.00 30.72  ? 131  HIS A O     1 
ATOM   1076  C CB    . HIS A 1 131 ? -43.496  -33.699  17.940  1.00 28.08  ? 131  HIS A CB    1 
ATOM   1077  C CG    . HIS A 1 131 ? -43.579  -32.222  18.171  1.00 33.62  ? 131  HIS A CG    1 
ATOM   1078  N ND1   . HIS A 1 131 ? -42.447  -31.445  18.354  1.00 35.04  ? 131  HIS A ND1   1 
ATOM   1079  C CD2   . HIS A 1 131 ? -44.644  -31.371  18.216  1.00 27.42  ? 131  HIS A CD2   1 
ATOM   1080  C CE1   . HIS A 1 131 ? -42.810  -30.171  18.486  1.00 30.45  ? 131  HIS A CE1   1 
ATOM   1081  N NE2   . HIS A 1 131 ? -44.136  -30.115  18.395  1.00 29.79  ? 131  HIS A NE2   1 
ATOM   1082  N N     . THR A 1 132 ? -45.010  -34.291  20.502  1.00 30.26  ? 132  THR A N     1 
ATOM   1083  C CA    . THR A 1 132 ? -45.861  -33.717  21.538  1.00 30.06  ? 132  THR A CA    1 
ATOM   1084  C C     . THR A 1 132 ? -45.630  -34.460  22.853  1.00 33.44  ? 132  THR A C     1 
ATOM   1085  O O     . THR A 1 132 ? -45.749  -35.681  22.917  1.00 30.55  ? 132  THR A O     1 
ATOM   1086  C CB    . THR A 1 132 ? -47.333  -33.727  21.123  1.00 28.34  ? 132  THR A CB    1 
ATOM   1087  O OG1   . THR A 1 132 ? -48.006  -33.402  22.336  1.00 29.11  ? 132  THR A OG1   1 
ATOM   1088  C CG2   . THR A 1 132 ? -47.805  -35.090  20.644  1.00 30.04  ? 132  THR A CG2   1 
ATOM   1089  N N     . PRO A 1 133 ? -45.335  -33.737  23.964  1.00 36.29  ? 133  PRO A N     1 
ATOM   1090  C CA    . PRO A 1 133 ? -45.236  -34.384  25.277  1.00 32.10  ? 133  PRO A CA    1 
ATOM   1091  C C     . PRO A 1 133 ? -46.549  -35.033  25.722  1.00 30.58  ? 133  PRO A C     1 
ATOM   1092  O O     . PRO A 1 133 ? -46.532  -35.913  26.574  1.00 29.37  ? 133  PRO A O     1 
ATOM   1093  C CB    . PRO A 1 133 ? -44.724  -33.295  26.214  1.00 31.40  ? 133  PRO A CB    1 
ATOM   1094  C CG    . PRO A 1 133 ? -44.955  -31.988  25.457  1.00 33.55  ? 133  PRO A CG    1 
ATOM   1095  C CD    . PRO A 1 133 ? -45.123  -32.271  23.988  1.00 35.58  ? 133  PRO A CD    1 
ATOM   1096  N N     . LEU A 1 134 ? -47.679  -34.665  25.091  1.00 29.90  ? 134  LEU A N     1 
ATOM   1097  C CA    . LEU A 1 134 ? -48.942  -35.328  25.400  1.00 29.40  ? 134  LEU A CA    1 
ATOM   1098  C C     . LEU A 1 134 ? -48.820  -36.850  25.276  1.00 32.59  ? 134  LEU A C     1 
ATOM   1099  O O     . LEU A 1 134 ? -49.452  -37.579  26.031  1.00 29.23  ? 134  LEU A O     1 
ATOM   1100  C CB    . LEU A 1 134 ? -50.133  -34.821  24.578  1.00 31.48  ? 134  LEU A CB    1 
ATOM   1101  C CG    . LEU A 1 134 ? -50.401  -33.305  24.641  1.00 30.57  ? 134  LEU A CG    1 
ATOM   1102  C CD1   . LEU A 1 134 ? -51.543  -32.990  23.638  1.00 28.31  ? 134  LEU A CD1   1 
ATOM   1103  C CD2   . LEU A 1 134 ? -50.802  -32.929  26.082  1.00 29.95  ? 134  LEU A CD2   1 
ATOM   1104  N N     . TYR A 1 135 ? -48.015  -37.335  24.319  1.00 33.26  ? 135  TYR A N     1 
ATOM   1105  C CA    . TYR A 1 135 ? -47.987  -38.763  24.022  1.00 30.58  ? 135  TYR A CA    1 
ATOM   1106  C C     . TYR A 1 135 ? -47.647  -39.574  25.277  1.00 33.65  ? 135  TYR A C     1 
ATOM   1107  O O     . TYR A 1 135 ? -48.291  -40.576  25.569  1.00 33.61  ? 135  TYR A O     1 
ATOM   1108  C CB    . TYR A 1 135 ? -47.065  -39.065  22.835  1.00 30.57  ? 135  TYR A CB    1 
ATOM   1109  C CG    . TYR A 1 135 ? -47.135  -40.518  22.403  1.00 29.56  ? 135  TYR A CG    1 
ATOM   1110  C CD1   . TYR A 1 135 ? -48.123  -40.943  21.512  1.00 28.49  ? 135  TYR A CD1   1 
ATOM   1111  C CD2   . TYR A 1 135 ? -46.220  -41.462  22.888  1.00 26.07  ? 135  TYR A CD2   1 
ATOM   1112  C CE1   . TYR A 1 135 ? -48.194  -42.274  21.099  1.00 28.72  ? 135  TYR A CE1   1 
ATOM   1113  C CE2   . TYR A 1 135 ? -46.269  -42.790  22.481  1.00 25.59  ? 135  TYR A CE2   1 
ATOM   1114  C CZ    . TYR A 1 135 ? -47.269  -43.187  21.588  1.00 28.61  ? 135  TYR A CZ    1 
ATOM   1115  O OH    . TYR A 1 135 ? -47.389  -44.472  21.174  1.00 30.40  ? 135  TYR A OH    1 
ATOM   1116  N N     . ASP A 1 136 ? -46.618  -39.165  26.028  1.00 36.04  ? 136  ASP A N     1 
ATOM   1117  C CA    . ASP A 1 136 ? -46.225  -39.886  27.234  1.00 42.11  ? 136  ASP A CA    1 
ATOM   1118  C C     . ASP A 1 136 ? -46.893  -39.337  28.497  1.00 44.23  ? 136  ASP A C     1 
ATOM   1119  O O     . ASP A 1 136 ? -47.116  -40.090  29.425  1.00 41.41  ? 136  ASP A O     1 
ATOM   1120  C CB    . ASP A 1 136 ? -44.721  -39.899  27.430  1.00 46.02  ? 136  ASP A CB    1 
ATOM   1121  C CG    . ASP A 1 136 ? -43.940  -40.707  26.396  1.00 54.84  ? 136  ASP A CG    1 
ATOM   1122  O OD1   . ASP A 1 136 ? -44.414  -41.839  26.024  1.00 50.27  ? 136  ASP A OD1   1 
ATOM   1123  O OD2   . ASP A 1 136 ? -42.874  -40.196  25.961  1.00 50.53  ? 136  ASP A OD2   1 
ATOM   1124  N N     . ASP A 1 137 ? -47.206  -38.034  28.536  1.00 46.13  ? 137  ASP A N     1 
ATOM   1125  C CA    . ASP A 1 137 ? -47.596  -37.339  29.763  1.00 48.25  ? 137  ASP A CA    1 
ATOM   1126  C C     . ASP A 1 137 ? -49.105  -37.325  29.982  1.00 48.31  ? 137  ASP A C     1 
ATOM   1127  O O     . ASP A 1 137 ? -49.548  -37.164  31.109  1.00 46.07  ? 137  ASP A O     1 
ATOM   1128  C CB    . ASP A 1 137 ? -47.109  -35.899  29.826  1.00 52.01  ? 137  ASP A CB    1 
ATOM   1129  C CG    . ASP A 1 137 ? -45.600  -35.748  29.981  1.00 68.44  ? 137  ASP A CG    1 
ATOM   1130  O OD1   . ASP A 1 137 ? -44.926  -36.773  30.273  1.00 61.70  ? 137  ASP A OD1   1 
ATOM   1131  O OD2   . ASP A 1 137 ? -45.107  -34.614  29.800  1.00 76.25  ? 137  ASP A OD2   1 
ATOM   1132  N N     . ASP A 1 138 ? -49.891  -37.485  28.909  1.00 46.66  ? 138  ASP A N     1 
ATOM   1133  C CA    . ASP A 1 138 ? -51.339  -37.346  28.982  1.00 41.03  ? 138  ASP A CA    1 
ATOM   1134  C C     . ASP A 1 138 ? -51.982  -37.997  27.754  1.00 40.34  ? 138  ASP A C     1 
ATOM   1135  O O     . ASP A 1 138 ? -52.510  -37.318  26.852  1.00 33.29  ? 138  ASP A O     1 
ATOM   1136  C CB    . ASP A 1 138 ? -51.732  -35.896  29.219  1.00 40.87  ? 138  ASP A CB    1 
ATOM   1137  C CG    . ASP A 1 138 ? -53.201  -35.616  29.509  1.00 41.88  ? 138  ASP A CG    1 
ATOM   1138  O OD1   . ASP A 1 138 ? -53.993  -36.567  29.575  1.00 41.44  ? 138  ASP A OD1   1 
ATOM   1139  O OD2   . ASP A 1 138 ? -53.566  -34.426  29.633  1.00 46.18  ? 138  ASP A OD2   1 
ATOM   1140  N N     . PHE A 1 139 ? -51.966  -39.334  27.770  1.00 34.33  ? 139  PHE A N     1 
ATOM   1141  C CA    . PHE A 1 139 ? -52.349  -40.105  26.603  1.00 38.57  ? 139  PHE A CA    1 
ATOM   1142  C C     . PHE A 1 139 ? -53.767  -39.729  26.151  1.00 38.81  ? 139  PHE A C     1 
ATOM   1143  O O     . PHE A 1 139 ? -53.996  -39.534  24.961  1.00 39.11  ? 139  PHE A O     1 
ATOM   1144  C CB    . PHE A 1 139 ? -52.086  -41.605  26.794  1.00 33.42  ? 139  PHE A CB    1 
ATOM   1145  C CG    . PHE A 1 139 ? -52.277  -42.389  25.499  1.00 33.63  ? 139  PHE A CG    1 
ATOM   1146  C CD1   . PHE A 1 139 ? -51.363  -42.272  24.443  1.00 33.18  ? 139  PHE A CD1   1 
ATOM   1147  C CD2   . PHE A 1 139 ? -53.349  -43.254  25.344  1.00 33.30  ? 139  PHE A CD2   1 
ATOM   1148  C CE1   . PHE A 1 139 ? -51.532  -43.000  23.260  1.00 33.50  ? 139  PHE A CE1   1 
ATOM   1149  C CE2   . PHE A 1 139 ? -53.509  -43.984  24.163  1.00 37.81  ? 139  PHE A CE2   1 
ATOM   1150  C CZ    . PHE A 1 139 ? -52.603  -43.847  23.108  1.00 35.08  ? 139  PHE A CZ    1 
ATOM   1151  N N     . PRO A 1 140 ? -54.771  -39.620  27.056  1.00 37.37  ? 140  PRO A N     1 
ATOM   1152  C CA    . PRO A 1 140 ? -56.115  -39.233  26.643  1.00 34.75  ? 140  PRO A CA    1 
ATOM   1153  C C     . PRO A 1 140 ? -56.151  -37.930  25.852  1.00 31.99  ? 140  PRO A C     1 
ATOM   1154  O O     . PRO A 1 140 ? -56.878  -37.814  24.868  1.00 35.56  ? 140  PRO A O     1 
ATOM   1155  C CB    . PRO A 1 140 ? -56.951  -39.244  27.941  1.00 33.45  ? 140  PRO A CB    1 
ATOM   1156  C CG    . PRO A 1 140 ? -56.115  -40.138  28.867  1.00 34.66  ? 140  PRO A CG    1 
ATOM   1157  C CD    . PRO A 1 140 ? -54.680  -39.906  28.505  1.00 36.41  ? 140  PRO A CD    1 
ATOM   1158  N N     . ALA A 1 141 ? -55.357  -36.954  26.271  1.00 29.85  ? 141  ALA A N     1 
ATOM   1159  C CA    . ALA A 1 141 ? -55.287  -35.681  25.561  1.00 31.67  ? 141  ALA A CA    1 
ATOM   1160  C C     . ALA A 1 141 ? -54.547  -35.848  24.221  1.00 32.23  ? 141  ALA A C     1 
ATOM   1161  O O     . ALA A 1 141 ? -54.854  -35.140  23.259  1.00 29.46  ? 141  ALA A O     1 
ATOM   1162  C CB    . ALA A 1 141 ? -54.638  -34.608  26.439  1.00 28.81  ? 141  ALA A CB    1 
ATOM   1163  N N     . TYR A 1 142 ? -53.572  -36.775  24.177  1.00 29.04  ? 142  TYR A N     1 
ATOM   1164  C CA    . TYR A 1 142 ? -52.891  -37.142  22.941  1.00 28.69  ? 142  TYR A CA    1 
ATOM   1165  C C     . TYR A 1 142 ? -53.916  -37.653  21.914  1.00 31.73  ? 142  TYR A C     1 
ATOM   1166  O O     . TYR A 1 142 ? -53.915  -37.208  20.751  1.00 28.42  ? 142  TYR A O     1 
ATOM   1167  C CB    . TYR A 1 142 ? -51.665  -38.054  23.091  1.00 26.40  ? 142  TYR A CB    1 
ATOM   1168  C CG    . TYR A 1 142 ? -51.190  -38.472  21.702  1.00 31.23  ? 142  TYR A CG    1 
ATOM   1169  C CD1   . TYR A 1 142 ? -50.446  -37.592  20.906  1.00 28.85  ? 142  TYR A CD1   1 
ATOM   1170  C CD2   . TYR A 1 142 ? -51.525  -39.710  21.160  1.00 26.35  ? 142  TYR A CD2   1 
ATOM   1171  C CE1   . TYR A 1 142 ? -50.057  -37.928  19.619  1.00 28.73  ? 142  TYR A CE1   1 
ATOM   1172  C CE2   . TYR A 1 142 ? -51.127  -40.064  19.877  1.00 27.99  ? 142  TYR A CE2   1 
ATOM   1173  C CZ    . TYR A 1 142 ? -50.407  -39.172  19.101  1.00 30.34  ? 142  TYR A CZ    1 
ATOM   1174  O OH    . TYR A 1 142 ? -50.047  -39.541  17.829  1.00 28.85  ? 142  TYR A OH    1 
ATOM   1175  N N     . LEU A 1 143 ? -54.814  -38.549  22.355  1.00 26.15  ? 143  LEU A N     1 
ATOM   1176  C CA    . LEU A 1 143 ? -55.853  -39.068  21.481  1.00 28.32  ? 143  LEU A CA    1 
ATOM   1177  C C     . LEU A 1 143 ? -56.679  -37.949  20.859  1.00 30.40  ? 143  LEU A C     1 
ATOM   1178  O O     . LEU A 1 143 ? -57.034  -38.040  19.683  1.00 38.58  ? 143  LEU A O     1 
ATOM   1179  C CB    . LEU A 1 143 ? -56.721  -40.107  22.175  1.00 24.87  ? 143  LEU A CB    1 
ATOM   1180  C CG    . LEU A 1 143 ? -55.945  -41.346  22.622  1.00 26.91  ? 143  LEU A CG    1 
ATOM   1181  C CD1   . LEU A 1 143 ? -56.970  -42.328  23.213  1.00 25.91  ? 143  LEU A CD1   1 
ATOM   1182  C CD2   . LEU A 1 143 ? -55.158  -41.997  21.416  1.00 23.65  ? 143  LEU A CD2   1 
ATOM   1183  N N     . THR A 1 144 ? -56.937  -36.885  21.627  1.00 31.20  ? 144  THR A N     1 
ATOM   1184  C CA    . THR A 1 144 ? -57.732  -35.776  21.118  1.00 34.92  ? 144  THR A CA    1 
ATOM   1185  C C     . THR A 1 144 ? -56.950  -35.036  20.036  1.00 27.86  ? 144  THR A C     1 
ATOM   1186  O O     . THR A 1 144 ? -57.522  -34.617  19.027  1.00 29.29  ? 144  THR A O     1 
ATOM   1187  C CB    . THR A 1 144 ? -58.172  -34.825  22.241  1.00 37.76  ? 144  THR A CB    1 
ATOM   1188  O OG1   . THR A 1 144 ? -58.971  -35.645  23.082  1.00 30.08  ? 144  THR A OG1   1 
ATOM   1189  C CG2   . THR A 1 144 ? -59.075  -33.698  21.739  1.00 28.81  ? 144  THR A CG2   1 
ATOM   1190  N N     . TYR A 1 145 ? -55.651  -34.857  20.276  1.00 26.01  ? 145  TYR A N     1 
ATOM   1191  C CA    . TYR A 1 145 ? -54.758  -34.165  19.356  1.00 26.43  ? 145  TYR A CA    1 
ATOM   1192  C C     . TYR A 1 145 ? -54.644  -34.962  18.050  1.00 28.41  ? 145  TYR A C     1 
ATOM   1193  O O     . TYR A 1 145 ? -54.792  -34.390  16.961  1.00 24.37  ? 145  TYR A O     1 
ATOM   1194  C CB    . TYR A 1 145 ? -53.427  -34.082  20.108  1.00 27.44  ? 145  TYR A CB    1 
ATOM   1195  C CG    . TYR A 1 145 ? -52.212  -33.554  19.363  1.00 28.83  ? 145  TYR A CG    1 
ATOM   1196  C CD1   . TYR A 1 145 ? -51.911  -32.189  19.366  1.00 26.03  ? 145  TYR A CD1   1 
ATOM   1197  C CD2   . TYR A 1 145 ? -51.355  -34.414  18.682  1.00 27.89  ? 145  TYR A CD2   1 
ATOM   1198  C CE1   . TYR A 1 145 ? -50.778  -31.701  18.740  1.00 28.51  ? 145  TYR A CE1   1 
ATOM   1199  C CE2   . TYR A 1 145 ? -50.231  -33.943  18.017  1.00 29.21  ? 145  TYR A CE2   1 
ATOM   1200  C CZ    . TYR A 1 145 ? -49.932  -32.583  18.072  1.00 31.16  ? 145  TYR A CZ    1 
ATOM   1201  O OH    . TYR A 1 145 ? -48.823  -32.100  17.441  1.00 30.90  ? 145  TYR A OH    1 
ATOM   1202  N N     . LEU A 1 146 ? -54.422  -36.281  18.178  1.00 24.22  ? 146  LEU A N     1 
ATOM   1203  C CA    . LEU A 1 146 ? -54.336  -37.153  17.018  1.00 25.67  ? 146  LEU A CA    1 
ATOM   1204  C C     . LEU A 1 146 ? -55.625  -37.035  16.205  1.00 27.32  ? 146  LEU A C     1 
ATOM   1205  O O     . LEU A 1 146 ? -55.592  -36.746  14.990  1.00 26.03  ? 146  LEU A O     1 
ATOM   1206  C CB    . LEU A 1 146 ? -54.040  -38.592  17.456  1.00 22.86  ? 146  LEU A CB    1 
ATOM   1207  C CG    . LEU A 1 146 ? -54.161  -39.658  16.364  1.00 21.47  ? 146  LEU A CG    1 
ATOM   1208  C CD1   . LEU A 1 146 ? -53.171  -39.394  15.198  1.00 20.61  ? 146  LEU A CD1   1 
ATOM   1209  C CD2   . LEU A 1 146 ? -53.927  -41.036  17.018  1.00 18.63  ? 146  LEU A CD2   1 
ATOM   1210  N N     . GLN A 1 147 ? -56.764  -37.172  16.908  1.00 25.38  ? 147  GLN A N     1 
ATOM   1211  C CA    . GLN A 1 147 ? -58.052  -37.145  16.238  1.00 26.61  ? 147  GLN A CA    1 
ATOM   1212  C C     . GLN A 1 147 ? -58.297  -35.802  15.544  1.00 29.18  ? 147  GLN A C     1 
ATOM   1213  O O     . GLN A 1 147 ? -58.813  -35.751  14.425  1.00 27.32  ? 147  GLN A O     1 
ATOM   1214  C CB    . GLN A 1 147 ? -59.178  -37.485  17.196  1.00 27.91  ? 147  GLN A CB    1 
ATOM   1215  C CG    . GLN A 1 147 ? -60.512  -37.521  16.459  1.00 35.32  ? 147  GLN A CG    1 
ATOM   1216  C CD    . GLN A 1 147 ? -61.607  -38.193  17.252  1.00 41.28  ? 147  GLN A CD    1 
ATOM   1217  O OE1   . GLN A 1 147 ? -61.420  -39.256  17.860  1.00 45.48  ? 147  GLN A OE1   1 
ATOM   1218  N NE2   . GLN A 1 147 ? -62.759  -37.553  17.246  1.00 34.92  ? 147  GLN A NE2   1 
ATOM   1219  N N     . LYS A 1 148 ? -57.959  -34.710  16.173  1.00 30.32  ? 148  LYS A N     1 
ATOM   1220  C CA    . LYS A 1 148 ? -58.136  -33.425  15.567  1.00 30.48  ? 148  LYS A CA    1 
ATOM   1221  C C     . LYS A 1 148 ? -57.286  -33.215  14.320  1.00 31.28  ? 148  LYS A C     1 
ATOM   1222  O O     . LYS A 1 148 ? -57.687  -32.533  13.428  1.00 30.44  ? 148  LYS A O     1 
ATOM   1223  C CB    . LYS A 1 148 ? -57.990  -32.316  16.590  1.00 31.43  ? 148  LYS A CB    1 
ATOM   1224  C CG    . LYS A 1 148 ? -59.271  -31.573  16.858  1.00 37.74  ? 148  LYS A CG    1 
ATOM   1225  C CD    . LYS A 1 148 ? -60.353  -32.326  17.592  1.00 36.82  ? 148  LYS A CD    1 
ATOM   1226  C CE    . LYS A 1 148 ? -61.677  -31.718  17.206  1.00 36.83  ? 148  LYS A CE    1 
ATOM   1227  N NZ    . LYS A 1 148 ? -62.840  -32.282  17.905  1.00 34.31  ? 148  LYS A NZ    1 
ATOM   1228  N N     . SER A 1 149 ? -56.075  -33.738  14.318  1.00 29.43  ? 149  SER A N     1 
ATOM   1229  C CA    . SER A 1 149 ? -55.204  -33.655  13.170  1.00 26.54  ? 149  SER A CA    1 
ATOM   1230  C C     . SER A 1 149 ? -55.788  -34.416  12.000  1.00 25.83  ? 149  SER A C     1 
ATOM   1231  O O     . SER A 1 149 ? -55.688  -33.989  10.905  1.00 26.24  ? 149  SER A O     1 
ATOM   1232  C CB    . SER A 1 149 ? -53.765  -34.051  13.497  1.00 25.17  ? 149  SER A CB    1 
ATOM   1233  O OG    . SER A 1 149 ? -53.615  -35.384  13.826  1.00 25.28  ? 149  SER A OG    1 
ATOM   1234  N N     . VAL A 1 150 ? -56.363  -35.565  12.273  1.00 24.68  ? 150  VAL A N     1 
ATOM   1235  C CA    . VAL A 1 150 ? -57.011  -36.353  11.283  1.00 25.09  ? 150  VAL A CA    1 
ATOM   1236  C C     . VAL A 1 150 ? -58.239  -35.626  10.743  1.00 30.88  ? 150  VAL A C     1 
ATOM   1237  O O     . VAL A 1 150 ? -58.481  -35.637  9.576   1.00 32.08  ? 150  VAL A O     1 
ATOM   1238  C CB    . VAL A 1 150 ? -57.319  -37.771  11.766  1.00 24.31  ? 150  VAL A CB    1 
ATOM   1239  C CG1   . VAL A 1 150 ? -58.011  -38.549  10.694  1.00 24.97  ? 150  VAL A CG1   1 
ATOM   1240  C CG2   . VAL A 1 150 ? -56.060  -38.476  12.152  1.00 21.10  ? 150  VAL A CG2   1 
ATOM   1241  N N     . GLU A 1 151 ? -58.970  -34.964  11.619  1.00 27.75  ? 151  GLU A N     1 
ATOM   1242  C CA    . GLU A 1 151 ? -60.148  -34.207  11.284  1.00 27.90  ? 151  GLU A CA    1 
ATOM   1243  C C     . GLU A 1 151 ? -59.852  -33.040  10.340  1.00 28.30  ? 151  GLU A C     1 
ATOM   1244  O O     . GLU A 1 151 ? -60.612  -32.747  9.470   1.00 26.17  ? 151  GLU A O     1 
ATOM   1245  C CB    . GLU A 1 151 ? -60.865  -33.762  12.554  1.00 30.40  ? 151  GLU A CB    1 
ATOM   1246  C CG    . GLU A 1 151 ? -62.240  -33.184  12.348  1.00 33.28  ? 151  GLU A CG    1 
ATOM   1247  C CD    . GLU A 1 151 ? -62.955  -32.838  13.625  1.00 38.36  ? 151  GLU A CD    1 
ATOM   1248  O OE1   . GLU A 1 151 ? -62.733  -33.458  14.640  1.00 42.41  ? 151  GLU A OE1   1 
ATOM   1249  O OE2   . GLU A 1 151 ? -63.781  -31.961  13.615  1.00 46.59  ? 151  GLU A OE2   1 
ATOM   1250  N N     . VAL A 1 152 ? -58.728  -32.383  10.520  1.00 25.49  ? 152  VAL A N     1 
ATOM   1251  C CA    . VAL A 1 152 ? -58.355  -31.303  9.641   1.00 27.21  ? 152  VAL A CA    1 
ATOM   1252  C C     . VAL A 1 152 ? -58.167  -31.792  8.204   1.00 29.92  ? 152  VAL A C     1 
ATOM   1253  O O     . VAL A 1 152 ? -58.531  -31.130  7.288   1.00 29.37  ? 152  VAL A O     1 
ATOM   1254  C CB    . VAL A 1 152 ? -57.103  -30.579  10.127  1.00 26.08  ? 152  VAL A CB    1 
ATOM   1255  C CG1   . VAL A 1 152 ? -56.589  -29.620  9.098   1.00 23.14  ? 152  VAL A CG1   1 
ATOM   1256  C CG2   . VAL A 1 152 ? -57.370  -29.881  11.415  1.00 23.81  ? 152  VAL A CG2   1 
ATOM   1257  N N     . LEU A 1 153 ? -57.554  -32.951  8.056   1.00 28.44  ? 153  LEU A N     1 
ATOM   1258  C CA    . LEU A 1 153 ? -57.349  -33.610  6.801   1.00 27.88  ? 153  LEU A CA    1 
ATOM   1259  C C     . LEU A 1 153 ? -58.670  -34.010  6.163   1.00 25.24  ? 153  LEU A C     1 
ATOM   1260  O O     . LEU A 1 153 ? -58.792  -34.002  4.996   1.00 24.57  ? 153  LEU A O     1 
ATOM   1261  C CB    . LEU A 1 153 ? -56.407  -34.799  6.961   1.00 26.60  ? 153  LEU A CB    1 
ATOM   1262  C CG    . LEU A 1 153 ? -54.970  -34.489  7.263   1.00 23.24  ? 153  LEU A CG    1 
ATOM   1263  C CD1   . LEU A 1 153 ? -54.216  -35.719  7.654   1.00 21.87  ? 153  LEU A CD1   1 
ATOM   1264  C CD2   . LEU A 1 153 ? -54.312  -33.786  6.115   1.00 22.43  ? 153  LEU A CD2   1 
ATOM   1265  N N     . CYS A 1 154 ? -59.611  -34.428  6.978   1.00 25.67  ? 154  CYS A N     1 
ATOM   1266  C CA    . CYS A 1 154 ? -60.962  -34.805  6.599   1.00 26.78  ? 154  CYS A CA    1 
ATOM   1267  C C     . CYS A 1 154 ? -61.889  -33.683  6.161   1.00 29.93  ? 154  CYS A C     1 
ATOM   1268  O O     . CYS A 1 154 ? -62.853  -33.900  5.499   1.00 27.30  ? 154  CYS A O     1 
ATOM   1269  C CB    . CYS A 1 154 ? -61.643  -35.505  7.754   1.00 25.55  ? 154  CYS A CB    1 
ATOM   1270  S SG    . CYS A 1 154 ? -61.186  -37.158  8.087   1.00 29.53  ? 154  CYS A SG    1 
ATOM   1271  N N     . ARG A 1 155 ? -61.622  -32.487  6.625   1.00 32.03  ? 155  ARG A N     1 
ATOM   1272  C CA    . ARG A 1 155 ? -62.474  -31.370  6.354   1.00 33.65  ? 155  ARG A CA    1 
ATOM   1273  C C     . ARG A 1 155 ? -61.965  -30.236  5.508   1.00 36.58  ? 155  ARG A C     1 
ATOM   1274  O O     . ARG A 1 155 ? -62.705  -29.363  5.196   1.00 35.16  ? 155  ARG A O     1 
ATOM   1275  C CB    . ARG A 1 155 ? -62.959  -30.821  7.682   1.00 29.34  ? 155  ARG A CB    1 
ATOM   1276  C CG    . ARG A 1 155 ? -63.715  -31.825  8.501   1.00 32.41  ? 155  ARG A CG    1 
ATOM   1277  C CD    . ARG A 1 155 ? -63.970  -31.319  9.887   1.00 37.03  ? 155  ARG A CD    1 
ATOM   1278  N NE    . ARG A 1 155 ? -64.734  -30.097  9.866   1.00 43.65  ? 155  ARG A NE    1 
ATOM   1279  C CZ    . ARG A 1 155 ? -65.248  -29.507  10.924  1.00 44.99  ? 155  ARG A CZ    1 
ATOM   1280  N NH1   . ARG A 1 155 ? -65.103  -30.019  12.121  1.00 37.46  ? 155  ARG A NH1   1 
ATOM   1281  N NH2   . ARG A 1 155 ? -65.913  -28.399  10.769  1.00 41.87  ? 155  ARG A NH2   1 
ATOM   1282  N N     . ASN A 1 156 ? -60.711  -30.242  5.131   1.00 30.70  ? 156  ASN A N     1 
ATOM   1283  C CA    . ASN A 1 156 ? -60.195  -29.126  4.381   1.00 29.61  ? 156  ASN A CA    1 
ATOM   1284  C C     . ASN A 1 156 ? -59.605  -29.397  3.028   1.00 29.01  ? 156  ASN A C     1 
ATOM   1285  O O     . ASN A 1 156 ? -59.009  -28.542  2.469   1.00 29.19  ? 156  ASN A O     1 
ATOM   1286  C CB    . ASN A 1 156 ? -59.157  -28.410  5.231   1.00 30.54  ? 156  ASN A CB    1 
ATOM   1287  C CG    . ASN A 1 156 ? -59.752  -27.726  6.413   1.00 32.23  ? 156  ASN A CG    1 
ATOM   1288  O OD1   . ASN A 1 156 ? -60.084  -26.590  6.335   1.00 37.57  ? 156  ASN A OD1   1 
ATOM   1289  N ND2   . ASN A 1 156 ? -59.872  -28.409  7.502   1.00 31.13  ? 156  ASN A ND2   1 
ATOM   1290  N N     . TYR A 1 157 ? -59.829  -30.560  2.468   1.00 27.97  ? 157  TYR A N     1 
ATOM   1291  C CA    . TYR A 1 157 ? -59.132  -30.945  1.245   1.00 29.58  ? 157  TYR A CA    1 
ATOM   1292  C C     . TYR A 1 157 ? -60.069  -31.584  0.222   1.00 32.62  ? 157  TYR A C     1 
ATOM   1293  O O     . TYR A 1 157 ? -59.593  -32.074  -0.797  1.00 34.08  ? 157  TYR A O     1 
ATOM   1294  C CB    . TYR A 1 157 ? -57.947  -31.860  1.609   1.00 26.51  ? 157  TYR A CB    1 
ATOM   1295  C CG    . TYR A 1 157 ? -56.956  -31.128  2.503   1.00 28.35  ? 157  TYR A CG    1 
ATOM   1296  C CD1   . TYR A 1 157 ? -56.099  -30.172  1.964   1.00 25.81  ? 157  TYR A CD1   1 
ATOM   1297  C CD2   . TYR A 1 157 ? -56.951  -31.300  3.891   1.00 24.21  ? 157  TYR A CD2   1 
ATOM   1298  C CE1   . TYR A 1 157 ? -55.234  -29.445  2.769   1.00 25.12  ? 157  TYR A CE1   1 
ATOM   1299  C CE2   . TYR A 1 157 ? -56.104  -30.575  4.706   1.00 21.44  ? 157  TYR A CE2   1 
ATOM   1300  C CZ    . TYR A 1 157 ? -55.253  -29.640  4.143   1.00 24.19  ? 157  TYR A CZ    1 
ATOM   1301  O OH    . TYR A 1 157 ? -54.375  -28.940  4.926   1.00 26.63  ? 157  TYR A OH    1 
ATOM   1302  N N     . GLY A 1 158 ? -61.382  -31.587  0.491   1.00 28.81  ? 158  GLY A N     1 
ATOM   1303  C CA    . GLY A 1 158 ? -62.330  -32.250  -0.389  1.00 30.57  ? 158  GLY A CA    1 
ATOM   1304  C C     . GLY A 1 158 ? -62.329  -33.764  -0.140  1.00 35.58  ? 158  GLY A C     1 
ATOM   1305  O O     . GLY A 1 158 ? -61.792  -34.224  0.877   1.00 28.12  ? 158  GLY A O     1 
ATOM   1306  N N     . PRO A 1 159 ? -62.913  -34.580  -1.058  1.00 35.91  ? 159  PRO A N     1 
ATOM   1307  C CA    . PRO A 1 159 ? -62.925  -36.034  -0.895  1.00 38.83  ? 159  PRO A CA    1 
ATOM   1308  C C     . PRO A 1 159 ? -61.522  -36.643  -0.883  1.00 34.17  ? 159  PRO A C     1 
ATOM   1309  O O     . PRO A 1 159 ? -60.686  -36.307  -1.714  1.00 33.03  ? 159  PRO A O     1 
ATOM   1310  C CB    . PRO A 1 159 ? -63.779  -36.540  -2.073  1.00 38.19  ? 159  PRO A CB    1 
ATOM   1311  C CG    . PRO A 1 159 ? -64.245  -35.310  -2.845  1.00 38.16  ? 159  PRO A CG    1 
ATOM   1312  C CD    . PRO A 1 159 ? -63.536  -34.115  -2.314  1.00 40.93  ? 159  PRO A CD    1 
ATOM   1313  N N     . VAL A 1 160 ? -61.261  -37.531  0.075   1.00 30.38  ? 160  VAL A N     1 
ATOM   1314  C CA    . VAL A 1 160 ? -59.928  -38.081  0.264   1.00 31.49  ? 160  VAL A CA    1 
ATOM   1315  C C     . VAL A 1 160 ? -59.974  -39.557  -0.124  1.00 29.27  ? 160  VAL A C     1 
ATOM   1316  O O     . VAL A 1 160 ? -60.921  -40.249  0.228   1.00 25.31  ? 160  VAL A O     1 
ATOM   1317  C CB    . VAL A 1 160 ? -59.655  -37.878  1.767   1.00 29.80  ? 160  VAL A CB    1 
ATOM   1318  C CG1   . VAL A 1 160 ? -58.440  -38.629  2.276   1.00 26.65  ? 160  VAL A CG1   1 
ATOM   1319  C CG2   . VAL A 1 160 ? -59.482  -36.407  2.118   1.00 35.03  ? 160  VAL A CG2   1 
ATOM   1320  N N     . GLY A 1 161 ? -58.960  -40.037  -0.852  1.00 29.24  ? 161  GLY A N     1 
ATOM   1321  C CA    . GLY A 1 161 ? -58.966  -41.437  -1.261  1.00 23.22  ? 161  GLY A CA    1 
ATOM   1322  C C     . GLY A 1 161 ? -58.907  -42.379  -0.061  1.00 24.36  ? 161  GLY A C     1 
ATOM   1323  O O     . GLY A 1 161 ? -59.637  -43.374  -0.010  1.00 24.29  ? 161  GLY A O     1 
ATOM   1324  N N     . GLY A 1 162 ? -58.063  -42.043  0.922   1.00 23.46  ? 162  GLY A N     1 
ATOM   1325  C CA    . GLY A 1 162 ? -57.898  -42.923  2.062   1.00 23.11  ? 162  GLY A CA    1 
ATOM   1326  C C     . GLY A 1 162 ? -56.897  -42.380  3.081   1.00 25.16  ? 162  GLY A C     1 
ATOM   1327  O O     . GLY A 1 162 ? -56.235  -41.373  2.856   1.00 24.95  ? 162  GLY A O     1 
ATOM   1328  N N     . PHE A 1 163 ? -56.826  -43.080  4.217   1.00 23.43  ? 163  PHE A N     1 
ATOM   1329  C CA    . PHE A 1 163 ? -55.912  -42.818  5.305   1.00 23.46  ? 163  PHE A CA    1 
ATOM   1330  C C     . PHE A 1 163 ? -55.141  -44.104  5.548   1.00 26.36  ? 163  PHE A C     1 
ATOM   1331  O O     . PHE A 1 163 ? -55.704  -45.205  5.437   1.00 28.05  ? 163  PHE A O     1 
ATOM   1332  C CB    . PHE A 1 163 ? -56.710  -42.514  6.588   1.00 25.69  ? 163  PHE A CB    1 
ATOM   1333  C CG    . PHE A 1 163 ? -57.370  -41.143  6.524   1.00 25.57  ? 163  PHE A CG    1 
ATOM   1334  C CD1   . PHE A 1 163 ? -58.625  -40.976  5.924   1.00 26.74  ? 163  PHE A CD1   1 
ATOM   1335  C CD2   . PHE A 1 163 ? -56.686  -40.011  6.974   1.00 22.94  ? 163  PHE A CD2   1 
ATOM   1336  C CE1   . PHE A 1 163 ? -59.190  -39.705  5.808   1.00 26.36  ? 163  PHE A CE1   1 
ATOM   1337  C CE2   . PHE A 1 163 ? -57.259  -38.747  6.857   1.00 25.40  ? 163  PHE A CE2   1 
ATOM   1338  C CZ    . PHE A 1 163 ? -58.517  -38.597  6.295   1.00 24.34  ? 163  PHE A CZ    1 
ATOM   1339  N N     . TRP A 1 164 ? -53.865  -43.931  5.910   1.00 23.16  ? 164  TRP A N     1 
ATOM   1340  C CA    . TRP A 1 164 ? -52.948  -45.033  6.102   1.00 21.80  ? 164  TRP A CA    1 
ATOM   1341  C C     . TRP A 1 164 ? -52.348  -44.818  7.487   1.00 23.51  ? 164  TRP A C     1 
ATOM   1342  O O     . TRP A 1 164 ? -51.505  -43.929  7.694   1.00 24.27  ? 164  TRP A O     1 
ATOM   1343  C CB    . TRP A 1 164 ? -51.909  -45.000  4.962   1.00 20.65  ? 164  TRP A CB    1 
ATOM   1344  C CG    . TRP A 1 164 ? -51.251  -46.306  4.592   1.00 22.27  ? 164  TRP A CG    1 
ATOM   1345  C CD1   . TRP A 1 164 ? -51.554  -47.082  3.505   1.00 22.85  ? 164  TRP A CD1   1 
ATOM   1346  C CD2   . TRP A 1 164 ? -50.157  -46.983  5.275   1.00 20.18  ? 164  TRP A CD2   1 
ATOM   1347  N NE1   . TRP A 1 164 ? -50.744  -48.200  3.471   1.00 21.54  ? 164  TRP A NE1   1 
ATOM   1348  C CE2   . TRP A 1 164 ? -49.866  -48.161  4.524   1.00 18.94  ? 164  TRP A CE2   1 
ATOM   1349  C CE3   . TRP A 1 164 ? -49.404  -46.711  6.431   1.00 17.63  ? 164  TRP A CE3   1 
ATOM   1350  C CZ2   . TRP A 1 164 ? -48.868  -49.067  4.898   1.00 17.21  ? 164  TRP A CZ2   1 
ATOM   1351  C CZ3   . TRP A 1 164 ? -48.407  -47.601  6.803   1.00 22.93  ? 164  TRP A CZ3   1 
ATOM   1352  C CH2   . TRP A 1 164 ? -48.124  -48.767  6.031   1.00 20.58  ? 164  TRP A CH2   1 
ATOM   1353  N N     . PHE A 1 165 ? -52.839  -45.603  8.451   1.00 22.34  ? 165  PHE A N     1 
ATOM   1354  C CA    . PHE A 1 165 ? -52.501  -45.387  9.849   1.00 24.64  ? 165  PHE A CA    1 
ATOM   1355  C C     . PHE A 1 165 ? -51.362  -46.323  10.239  1.00 24.54  ? 165  PHE A C     1 
ATOM   1356  O O     . PHE A 1 165 ? -51.438  -47.536  10.037  1.00 21.10  ? 165  PHE A O     1 
ATOM   1357  C CB    . PHE A 1 165 ? -53.686  -45.592  10.806  1.00 21.26  ? 165  PHE A CB    1 
ATOM   1358  C CG    . PHE A 1 165 ? -54.643  -44.417  10.716  1.00 22.79  ? 165  PHE A CG    1 
ATOM   1359  C CD1   . PHE A 1 165 ? -54.269  -43.162  11.198  1.00 23.96  ? 165  PHE A CD1   1 
ATOM   1360  C CD2   . PHE A 1 165 ? -55.902  -44.550  10.116  1.00 22.26  ? 165  PHE A CD2   1 
ATOM   1361  C CE1   . PHE A 1 165 ? -55.152  -42.084  11.111  1.00 25.27  ? 165  PHE A CE1   1 
ATOM   1362  C CE2   . PHE A 1 165 ? -56.772  -43.465  10.022  1.00 20.22  ? 165  PHE A CE2   1 
ATOM   1363  C CZ    . PHE A 1 165 ? -56.399  -42.240  10.504  1.00 22.18  ? 165  PHE A CZ    1 
ATOM   1364  N N     . ASP A 1 166 ? -50.359  -45.753  10.901  1.00 26.20  ? 166  ASP A N     1 
ATOM   1365  C CA    . ASP A 1 166 ? -49.253  -46.553  11.371  1.00 26.31  ? 166  ASP A CA    1 
ATOM   1366  C C     . ASP A 1 166 ? -48.904  -46.225  12.829  1.00 28.52  ? 166  ASP A C     1 
ATOM   1367  O O     . ASP A 1 166 ? -48.535  -45.074  13.138  1.00 30.79  ? 166  ASP A O     1 
ATOM   1368  C CB    . ASP A 1 166 ? -48.104  -46.207  10.441  1.00 26.31  ? 166  ASP A CB    1 
ATOM   1369  C CG    . ASP A 1 166 ? -46.781  -46.815  10.872  1.00 34.22  ? 166  ASP A CG    1 
ATOM   1370  O OD1   . ASP A 1 166 ? -46.802  -48.022  11.314  1.00 34.16  ? 166  ASP A OD1   1 
ATOM   1371  O OD2   . ASP A 1 166 ? -45.767  -46.099  10.749  1.00 37.07  ? 166  ASP A OD2   1 
ATOM   1372  N N     . GLY A 1 167 ? -48.922  -47.213  13.735  1.00 35.94  ? 167  GLY A N     1 
ATOM   1373  C CA    . GLY A 1 167 ? -48.153  -46.969  14.970  1.00 55.79  ? 167  GLY A CA    1 
ATOM   1374  C C     . GLY A 1 167 ? -48.838  -47.315  16.306  1.00 66.39  ? 167  GLY A C     1 
ATOM   1375  O O     . GLY A 1 167 ? -48.284  -47.104  17.404  1.00 57.83  ? 167  GLY A O     1 
ATOM   1376  N N     . ASN A 1 168 ? -50.058  -47.856  16.214  1.00 71.13  ? 168  ASN A N     1 
ATOM   1377  C CA    . ASN A 1 168 ? -50.772  -48.310  17.405  1.00 61.51  ? 168  ASN A CA    1 
ATOM   1378  C C     . ASN A 1 168 ? -49.979  -49.439  18.070  1.00 68.33  ? 168  ASN A C     1 
ATOM   1379  O O     . ASN A 1 168 ? -50.112  -49.656  19.275  1.00 66.52  ? 168  ASN A O     1 
ATOM   1380  C CB    . ASN A 1 168 ? -52.215  -48.733  17.117  1.00 66.10  ? 168  ASN A CB    1 
ATOM   1381  C CG    . ASN A 1 168 ? -53.129  -47.587  16.742  1.00 60.57  ? 168  ASN A CG    1 
ATOM   1382  O OD1   . ASN A 1 168 ? -52.689  -46.506  16.333  1.00 53.54  ? 168  ASN A OD1   1 
ATOM   1383  N ND2   . ASN A 1 168 ? -54.423  -47.827  16.871  1.00 62.79  ? 168  ASN A ND2   1 
ATOM   1384  N N     . TRP A 1 169 ? -49.141  -50.135  17.271  1.00 69.50  ? 169  TRP A N     1 
ATOM   1385  C CA    . TRP A 1 169 ? -48.251  -51.200  17.727  1.00 64.43  ? 169  TRP A CA    1 
ATOM   1386  C C     . TRP A 1 169 ? -47.292  -50.707  18.828  1.00 60.10  ? 169  TRP A C     1 
ATOM   1387  O O     . TRP A 1 169 ? -46.699  -51.533  19.518  1.00 55.48  ? 169  TRP A O     1 
ATOM   1388  C CB    . TRP A 1 169 ? -47.474  -51.809  16.540  1.00 61.41  ? 169  TRP A CB    1 
ATOM   1389  C CG    . TRP A 1 169 ? -46.934  -50.775  15.576  1.00 66.10  ? 169  TRP A CG    1 
ATOM   1390  C CD1   . TRP A 1 169 ? -47.454  -50.437  14.359  1.00 49.35  ? 169  TRP A CD1   1 
ATOM   1391  C CD2   . TRP A 1 169 ? -45.791  -49.899  15.772  1.00 52.35  ? 169  TRP A CD2   1 
ATOM   1392  N NE1   . TRP A 1 169 ? -46.722  -49.433  13.782  1.00 37.49  ? 169  TRP A NE1   1 
ATOM   1393  C CE2   . TRP A 1 169 ? -45.698  -49.088  14.616  1.00 44.43  ? 169  TRP A CE2   1 
ATOM   1394  C CE3   . TRP A 1 169 ? -44.845  -49.743  16.798  1.00 45.49  ? 169  TRP A CE3   1 
ATOM   1395  C CZ2   . TRP A 1 169 ? -44.693  -48.141  14.462  1.00 49.58  ? 169  TRP A CZ2   1 
ATOM   1396  C CZ3   . TRP A 1 169 ? -43.856  -48.804  16.656  1.00 59.67  ? 169  TRP A CZ3   1 
ATOM   1397  C CH2   . TRP A 1 169 ? -43.802  -48.007  15.506  1.00 59.59  ? 169  TRP A CH2   1 
ATOM   1398  N N     . ASN A 1 170 ? -47.117  -49.378  18.985  1.00 52.72  ? 170  ASN A N     1 
ATOM   1399  C CA    . ASN A 1 170 ? -46.230  -48.866  20.010  1.00 43.17  ? 170  ASN A CA    1 
ATOM   1400  C C     . ASN A 1 170 ? -46.802  -49.096  21.415  1.00 44.72  ? 170  ASN A C     1 
ATOM   1401  O O     . ASN A 1 170 ? -46.052  -49.281  22.373  1.00 50.89  ? 170  ASN A O     1 
ATOM   1402  C CB    . ASN A 1 170 ? -45.847  -47.418  19.793  1.00 44.94  ? 170  ASN A CB    1 
ATOM   1403  C CG    . ASN A 1 170 ? -45.029  -46.895  20.966  1.00 55.04  ? 170  ASN A CG    1 
ATOM   1404  O OD1   . ASN A 1 170 ? -43.860  -47.268  21.092  1.00 64.43  ? 170  ASN A OD1   1 
ATOM   1405  N ND2   . ASN A 1 170 ? -45.588  -46.059  21.843  1.00 41.09  ? 170  ASN A ND2   1 
ATOM   1406  N N     . LYS A 1 171 ? -48.128  -49.036  21.563  1.00 50.37  ? 171  LYS A N     1 
ATOM   1407  C CA    . LYS A 1 171 ? -48.793  -49.338  22.829  1.00 54.40  ? 171  LYS A CA    1 
ATOM   1408  C C     . LYS A 1 171 ? -49.899  -50.354  22.542  1.00 64.67  ? 171  LYS A C     1 
ATOM   1409  O O     . LYS A 1 171 ? -51.057  -49.983  22.338  1.00 49.19  ? 171  LYS A O     1 
ATOM   1410  C CB    . LYS A 1 171 ? -49.407  -48.064  23.418  1.00 50.42  ? 171  LYS A CB    1 
ATOM   1411  C CG    . LYS A 1 171 ? -48.447  -46.982  23.885  1.00 51.95  ? 171  LYS A CG    1 
ATOM   1412  C CD    . LYS A 1 171 ? -49.109  -45.710  24.430  1.00 58.10  ? 171  LYS A CD    1 
ATOM   1413  C CE    . LYS A 1 171 ? -48.314  -45.253  25.630  1.00 66.07  ? 171  LYS A CE    1 
ATOM   1414  N NZ    . LYS A 1 171 ? -48.246  -43.801  25.830  1.00 60.62  ? 171  LYS A NZ    1 
ATOM   1415  N N     . LYS A 1 172 ? -49.525  -51.648  22.501  1.00 80.74  ? 172  LYS A N     1 
ATOM   1416  C CA    . LYS A 1 172 ? -50.433  -52.712  22.092  1.00 81.39  ? 172  LYS A CA    1 
ATOM   1417  C C     . LYS A 1 172 ? -51.582  -52.840  23.099  1.00 88.33  ? 172  LYS A C     1 
ATOM   1418  O O     . LYS A 1 172 ? -52.639  -53.342  22.730  1.00 75.34  ? 172  LYS A O     1 
ATOM   1419  C CB    . LYS A 1 172 ? -49.724  -54.059  21.895  1.00 82.72  ? 172  LYS A CB    1 
ATOM   1420  C CG    . LYS A 1 172 ? -48.847  -54.095  20.653  1.00 90.98  ? 172  LYS A CG    1 
ATOM   1421  C CD    . LYS A 1 172 ? -47.859  -55.235  20.477  1.00 92.97  ? 172  LYS A CD    1 
ATOM   1422  C CE    . LYS A 1 172 ? -48.438  -56.181  19.473  1.00 105.32 ? 172  LYS A CE    1 
ATOM   1423  N NZ    . LYS A 1 172 ? -47.714  -57.452  19.388  1.00 100.64 ? 172  LYS A NZ    1 
ATOM   1424  N N     . ASP A 1 173 ? -51.370  -52.378  24.350  1.00 85.04  ? 173  ASP A N     1 
ATOM   1425  C CA    . ASP A 1 173 ? -52.322  -52.578  25.435  1.00 85.49  ? 173  ASP A CA    1 
ATOM   1426  C C     . ASP A 1 173 ? -53.333  -51.435  25.585  1.00 78.68  ? 173  ASP A C     1 
ATOM   1427  O O     . ASP A 1 173 ? -54.388  -51.637  26.179  1.00 67.23  ? 173  ASP A O     1 
ATOM   1428  C CB    . ASP A 1 173 ? -51.617  -53.005  26.710  1.00 93.43  ? 173  ASP A CB    1 
ATOM   1429  C CG    . ASP A 1 173 ? -51.004  -54.398  26.649  1.00 105.98 ? 173  ASP A CG    1 
ATOM   1430  O OD1   . ASP A 1 173 ? -51.405  -55.202  25.750  1.00 79.11  ? 173  ASP A OD1   1 
ATOM   1431  O OD2   . ASP A 1 173 ? -50.103  -54.649  27.473  1.00 103.17 ? 173  ASP A OD2   1 
ATOM   1432  N N     . ALA A 1 174 ? -53.025  -50.251  25.037  1.00 65.95  ? 174  ALA A N     1 
ATOM   1433  C CA    . ALA A 1 174 ? -53.781  -49.043  25.327  1.00 51.83  ? 174  ALA A CA    1 
ATOM   1434  C C     . ALA A 1 174 ? -55.124  -49.056  24.604  1.00 49.45  ? 174  ALA A C     1 
ATOM   1435  O O     . ALA A 1 174 ? -55.308  -49.757  23.602  1.00 41.24  ? 174  ALA A O     1 
ATOM   1436  C CB    . ALA A 1 174 ? -52.972  -47.828  24.956  1.00 52.53  ? 174  ALA A CB    1 
ATOM   1437  N N     . ASP A 1 175 ? -56.062  -48.262  25.137  1.00 45.56  ? 175  ASP A N     1 
ATOM   1438  C CA    . ASP A 1 175 ? -57.306  -48.013  24.434  1.00 39.01  ? 175  ASP A CA    1 
ATOM   1439  C C     . ASP A 1 175 ? -57.076  -46.825  23.504  1.00 36.27  ? 175  ASP A C     1 
ATOM   1440  O O     . ASP A 1 175 ? -56.881  -45.706  23.980  1.00 39.41  ? 175  ASP A O     1 
ATOM   1441  C CB    . ASP A 1 175 ? -58.450  -47.794  25.418  1.00 40.83  ? 175  ASP A CB    1 
ATOM   1442  C CG    . ASP A 1 175 ? -59.839  -47.629  24.801  1.00 50.35  ? 175  ASP A CG    1 
ATOM   1443  O OD1   . ASP A 1 175 ? -59.951  -47.500  23.546  1.00 49.61  ? 175  ASP A OD1   1 
ATOM   1444  O OD2   . ASP A 1 175 ? -60.821  -47.632  25.576  1.00 56.52  ? 175  ASP A OD2   1 
ATOM   1445  N N     . TRP A 1 176 ? -57.112  -47.065  22.191  1.00 32.07  ? 176  TRP A N     1 
ATOM   1446  C CA    . TRP A 1 176 ? -56.831  -46.028  21.203  1.00 32.03  ? 176  TRP A CA    1 
ATOM   1447  C C     . TRP A 1 176 ? -58.103  -45.314  20.748  1.00 30.70  ? 176  TRP A C     1 
ATOM   1448  O O     . TRP A 1 176 ? -58.020  -44.387  19.936  1.00 29.62  ? 176  TRP A O     1 
ATOM   1449  C CB    . TRP A 1 176 ? -56.092  -46.596  19.976  1.00 32.32  ? 176  TRP A CB    1 
ATOM   1450  C CG    . TRP A 1 176 ? -54.630  -46.839  20.254  1.00 35.39  ? 176  TRP A CG    1 
ATOM   1451  C CD1   . TRP A 1 176 ? -54.069  -47.981  20.764  1.00 36.25  ? 176  TRP A CD1   1 
ATOM   1452  C CD2   . TRP A 1 176 ? -53.535  -45.929  19.998  1.00 30.23  ? 176  TRP A CD2   1 
ATOM   1453  N NE1   . TRP A 1 176 ? -52.716  -47.825  20.881  1.00 33.86  ? 176  TRP A NE1   1 
ATOM   1454  C CE2   . TRP A 1 176 ? -52.356  -46.592  20.405  1.00 29.87  ? 176  TRP A CE2   1 
ATOM   1455  C CE3   . TRP A 1 176 ? -53.445  -44.636  19.469  1.00 30.28  ? 176  TRP A CE3   1 
ATOM   1456  C CZ2   . TRP A 1 176 ? -51.098  -46.008  20.298  1.00 29.97  ? 176  TRP A CZ2   1 
ATOM   1457  C CZ3   . TRP A 1 176 ? -52.195  -44.061  19.356  1.00 32.30  ? 176  TRP A CZ3   1 
ATOM   1458  C CH2   . TRP A 1 176 ? -51.045  -44.739  19.760  1.00 31.43  ? 176  TRP A CH2   1 
ATOM   1459  N N     . HIS A 1 177 ? -59.270  -45.765  21.240  1.00 28.42  ? 177  HIS A N     1 
ATOM   1460  C CA    . HIS A 1 177 ? -60.526  -45.099  20.922  1.00 30.60  ? 177  HIS A CA    1 
ATOM   1461  C C     . HIS A 1 177 ? -60.709  -45.087  19.405  1.00 36.19  ? 177  HIS A C     1 
ATOM   1462  O O     . HIS A 1 177 ? -61.007  -44.041  18.809  1.00 32.79  ? 177  HIS A O     1 
ATOM   1463  C CB    . HIS A 1 177 ? -60.642  -43.722  21.615  1.00 31.81  ? 177  HIS A CB    1 
ATOM   1464  C CG    . HIS A 1 177 ? -60.799  -43.797  23.118  1.00 41.81  ? 177  HIS A CG    1 
ATOM   1465  N ND1   . HIS A 1 177 ? -61.991  -43.952  23.805  1.00 40.71  ? 177  HIS A ND1   1 
ATOM   1466  C CD2   . HIS A 1 177 ? -59.846  -43.802  24.061  1.00 38.98  ? 177  HIS A CD2   1 
ATOM   1467  C CE1   . HIS A 1 177 ? -61.749  -44.057  25.099  1.00 39.75  ? 177  HIS A CE1   1 
ATOM   1468  N NE2   . HIS A 1 177 ? -60.456  -43.945  25.273  1.00 39.81  ? 177  HIS A NE2   1 
ATOM   1469  N N     . LEU A 1 178 ? -60.558  -46.272  18.793  1.00 33.46  ? 178  LEU A N     1 
ATOM   1470  C CA    . LEU A 1 178 ? -60.681  -46.407  17.347  1.00 33.17  ? 178  LEU A CA    1 
ATOM   1471  C C     . LEU A 1 178 ? -62.111  -46.112  16.878  1.00 35.54  ? 178  LEU A C     1 
ATOM   1472  O O     . LEU A 1 178 ? -62.289  -45.445  15.852  1.00 34.89  ? 178  LEU A O     1 
ATOM   1473  C CB    . LEU A 1 178 ? -60.134  -47.733  16.808  1.00 31.89  ? 178  LEU A CB    1 
ATOM   1474  C CG    . LEU A 1 178 ? -58.651  -47.961  17.148  1.00 35.51  ? 178  LEU A CG    1 
ATOM   1475  C CD1   . LEU A 1 178 ? -58.157  -49.382  16.798  1.00 32.38  ? 178  LEU A CD1   1 
ATOM   1476  C CD2   . LEU A 1 178 ? -57.810  -46.877  16.461  1.00 28.21  ? 178  LEU A CD2   1 
ATOM   1477  N N     . PRO A 1 179 ? -63.171  -46.597  17.585  1.00 36.09  ? 179  PRO A N     1 
ATOM   1478  C CA    . PRO A 1 179 ? -64.547  -46.254  17.214  1.00 33.20  ? 179  PRO A CA    1 
ATOM   1479  C C     . PRO A 1 179 ? -64.755  -44.760  16.989  1.00 29.14  ? 179  PRO A C     1 
ATOM   1480  O O     . PRO A 1 179 ? -65.384  -44.363  16.015  1.00 31.13  ? 179  PRO A O     1 
ATOM   1481  C CB    . PRO A 1 179 ? -65.430  -46.945  18.279  1.00 32.35  ? 179  PRO A CB    1 
ATOM   1482  C CG    . PRO A 1 179 ? -64.536  -48.078  18.791  1.00 34.32  ? 179  PRO A CG    1 
ATOM   1483  C CD    . PRO A 1 179 ? -63.108  -47.550  18.716  1.00 37.44  ? 179  PRO A CD    1 
ATOM   1484  N N     . GLU A 1 180 ? -64.165  -43.936  17.852  1.00 29.81  ? 180  GLU A N     1 
ATOM   1485  C CA    . GLU A 1 180 ? -64.331  -42.488  17.768  1.00 33.04  ? 180  GLU A CA    1 
ATOM   1486  C C     . GLU A 1 180 ? -63.506  -41.917  16.616  1.00 33.19  ? 180  GLU A C     1 
ATOM   1487  O O     . GLU A 1 180 ? -64.002  -41.057  15.880  1.00 32.59  ? 180  GLU A O     1 
ATOM   1488  C CB    . GLU A 1 180 ? -64.117  -41.705  19.078  1.00 34.51  ? 180  GLU A CB    1 
ATOM   1489  C CG    . GLU A 1 180 ? -64.954  -42.220  20.245  1.00 37.99  ? 180  GLU A CG    1 
ATOM   1490  C CD    . GLU A 1 180 ? -64.324  -43.300  21.135  1.00 47.01  ? 180  GLU A CD    1 
ATOM   1491  O OE1   . GLU A 1 180 ? -64.072  -44.495  20.821  1.00 45.93  ? 180  GLU A OE1   1 
ATOM   1492  O OE2   . GLU A 1 180 ? -64.057  -42.886  22.276  1.00 52.18  ? 180  GLU A OE2   1 
ATOM   1493  N N     . LEU A 1 181 ? -62.246  -42.379  16.471  1.00 28.44  ? 181  LEU A N     1 
ATOM   1494  C CA    . LEU A 1 181 ? -61.394  -41.891  15.390  1.00 28.70  ? 181  LEU A CA    1 
ATOM   1495  C C     . LEU A 1 181 ? -61.992  -42.267  14.027  1.00 29.39  ? 181  LEU A C     1 
ATOM   1496  O O     . LEU A 1 181 ? -62.207  -41.403  13.178  1.00 28.25  ? 181  LEU A O     1 
ATOM   1497  C CB    . LEU A 1 181 ? -59.969  -42.405  15.560  1.00 25.71  ? 181  LEU A CB    1 
ATOM   1498  C CG    . LEU A 1 181 ? -58.976  -42.055  14.450  1.00 26.81  ? 181  LEU A CG    1 
ATOM   1499  C CD1   . LEU A 1 181 ? -58.753  -40.536  14.398  1.00 26.80  ? 181  LEU A CD1   1 
ATOM   1500  C CD2   . LEU A 1 181 ? -57.676  -42.829  14.720  1.00 24.34  ? 181  LEU A CD2   1 
ATOM   1501  N N     . TYR A 1 182 ? -62.249  -43.538  13.831  1.00 25.73  ? 182  TYR A N     1 
ATOM   1502  C CA    . TYR A 1 182 ? -62.790  -44.044  12.591  1.00 29.70  ? 182  TYR A CA    1 
ATOM   1503  C C     . TYR A 1 182 ? -64.176  -43.535  12.280  1.00 34.38  ? 182  TYR A C     1 
ATOM   1504  O O     . TYR A 1 182 ? -64.518  -43.362  11.147  1.00 33.15  ? 182  TYR A O     1 
ATOM   1505  C CB    . TYR A 1 182 ? -62.660  -45.544  12.496  1.00 25.10  ? 182  TYR A CB    1 
ATOM   1506  C CG    . TYR A 1 182 ? -61.253  -46.023  12.547  1.00 27.52  ? 182  TYR A CG    1 
ATOM   1507  C CD1   . TYR A 1 182 ? -60.216  -45.205  12.220  1.00 28.83  ? 182  TYR A CD1   1 
ATOM   1508  C CD2   . TYR A 1 182 ? -60.957  -47.292  12.928  1.00 26.28  ? 182  TYR A CD2   1 
ATOM   1509  C CE1   . TYR A 1 182 ? -58.931  -45.647  12.260  1.00 25.58  ? 182  TYR A CE1   1 
ATOM   1510  C CE2   . TYR A 1 182 ? -59.676  -47.728  12.980  1.00 26.66  ? 182  TYR A CE2   1 
ATOM   1511  C CZ    . TYR A 1 182 ? -58.673  -46.896  12.638  1.00 26.84  ? 182  TYR A CZ    1 
ATOM   1512  O OH    . TYR A 1 182 ? -57.416  -47.330  12.680  1.00 28.64  ? 182  TYR A OH    1 
ATOM   1513  N N     . GLY A 1 183 ? -64.973  -43.362  13.321  1.00 34.67  ? 183  GLY A N     1 
ATOM   1514  C CA    . GLY A 1 183 ? -66.299  -42.827  13.221  1.00 29.69  ? 183  GLY A CA    1 
ATOM   1515  C C     . GLY A 1 183 ? -66.317  -41.425  12.721  1.00 27.36  ? 183  GLY A C     1 
ATOM   1516  O O     . GLY A 1 183 ? -67.147  -41.067  11.957  1.00 31.26  ? 183  GLY A O     1 
ATOM   1517  N N     . MET A 1 184 ? -65.390  -40.624  13.194  1.00 27.73  ? 184  MET A N     1 
ATOM   1518  C CA    . MET A 1 184 ? -65.255  -39.284  12.738  1.00 26.18  ? 184  MET A CA    1 
ATOM   1519  C C     . MET A 1 184 ? -64.880  -39.291  11.267  1.00 28.32  ? 184  MET A C     1 
ATOM   1520  O O     . MET A 1 184 ? -65.402  -38.548  10.517  1.00 28.71  ? 184  MET A O     1 
ATOM   1521  C CB    . MET A 1 184 ? -64.221  -38.561  13.591  1.00 26.71  ? 184  MET A CB    1 
ATOM   1522  C CG    . MET A 1 184 ? -63.867  -37.142  13.211  1.00 25.63  ? 184  MET A CG    1 
ATOM   1523  S SD    . MET A 1 184 ? -62.785  -36.903  11.818  1.00 35.85  ? 184  MET A SD    1 
ATOM   1524  C CE    . MET A 1 184 ? -61.294  -37.565  12.455  1.00 34.62  ? 184  MET A CE    1 
ATOM   1525  N N     . ILE A 1 185 ? -63.989  -40.171  10.854  1.00 29.36  ? 185  ILE A N     1 
ATOM   1526  C CA    . ILE A 1 185 ? -63.592  -40.235  9.475   1.00 25.61  ? 185  ILE A CA    1 
ATOM   1527  C C     . ILE A 1 185 ? -64.773  -40.606  8.621   1.00 26.08  ? 185  ILE A C     1 
ATOM   1528  O O     . ILE A 1 185 ? -64.975  -40.040  7.617   1.00 25.34  ? 185  ILE A O     1 
ATOM   1529  C CB    . ILE A 1 185 ? -62.428  -41.200  9.235   1.00 26.06  ? 185  ILE A CB    1 
ATOM   1530  C CG1   . ILE A 1 185 ? -61.182  -40.712  9.912   1.00 22.14  ? 185  ILE A CG1   1 
ATOM   1531  C CG2   . ILE A 1 185 ? -62.163  -41.348  7.764   1.00 22.45  ? 185  ILE A CG2   1 
ATOM   1532  C CD1   . ILE A 1 185 ? -60.216  -41.807  10.184  1.00 24.02  ? 185  ILE A CD1   1 
ATOM   1533  N N     . ARG A 1 186 ? -65.571  -41.543  9.069   1.00 28.87  ? 186  ARG A N     1 
ATOM   1534  C CA    . ARG A 1 186 ? -66.745  -41.938  8.333   1.00 32.41  ? 186  ARG A CA    1 
ATOM   1535  C C     . ARG A 1 186 ? -67.741  -40.829  8.197   1.00 34.49  ? 186  ARG A C     1 
ATOM   1536  O O     . ARG A 1 186 ? -68.436  -40.753  7.233   1.00 41.21  ? 186  ARG A O     1 
ATOM   1537  C CB    . ARG A 1 186 ? -67.433  -43.119  8.946   1.00 29.95  ? 186  ARG A CB    1 
ATOM   1538  C CG    . ARG A 1 186 ? -66.761  -44.398  8.656   1.00 30.54  ? 186  ARG A CG    1 
ATOM   1539  C CD    . ARG A 1 186 ? -66.901  -44.867  7.240   1.00 29.03  ? 186  ARG A CD    1 
ATOM   1540  N NE    . ARG A 1 186 ? -65.889  -45.871  7.090   1.00 30.12  ? 186  ARG A NE    1 
ATOM   1541  C CZ    . ARG A 1 186 ? -65.014  -45.933  6.124   1.00 29.16  ? 186  ARG A CZ    1 
ATOM   1542  N NH1   . ARG A 1 186 ? -65.038  -45.097  5.134   1.00 28.96  ? 186  ARG A NH1   1 
ATOM   1543  N NH2   . ARG A 1 186 ? -64.136  -46.860  6.154   1.00 26.86  ? 186  ARG A NH2   1 
ATOM   1544  N N     . HIS A 1 187 ? -67.882  -40.030  9.223   1.00 34.71  ? 187  HIS A N     1 
ATOM   1545  C CA    . HIS A 1 187 ? -68.785  -38.935  9.165   1.00 31.91  ? 187  HIS A CA    1 
ATOM   1546  C C     . HIS A 1 187 ? -68.405  -37.888  8.116   1.00 32.24  ? 187  HIS A C     1 
ATOM   1547  O O     . HIS A 1 187 ? -69.236  -37.470  7.371   1.00 37.35  ? 187  HIS A O     1 
ATOM   1548  C CB    . HIS A 1 187 ? -68.951  -38.344  10.566  1.00 33.43  ? 187  HIS A CB    1 
ATOM   1549  C CG    . HIS A 1 187 ? -69.702  -37.065  10.595  1.00 42.07  ? 187  HIS A CG    1 
ATOM   1550  N ND1   . HIS A 1 187 ? -71.065  -37.015  10.677  1.00 49.12  ? 187  HIS A ND1   1 
ATOM   1551  C CD2   . HIS A 1 187 ? -69.286  -35.789  10.502  1.00 46.01  ? 187  HIS A CD2   1 
ATOM   1552  C CE1   . HIS A 1 187 ? -71.459  -35.762  10.643  1.00 50.65  ? 187  HIS A CE1   1 
ATOM   1553  N NE2   . HIS A 1 187 ? -70.398  -34.998  10.532  1.00 46.60  ? 187  HIS A NE2   1 
ATOM   1554  N N     . TYR A 1 188 ? -67.152  -37.492  8.032   1.00 32.08  ? 188  TYR A N     1 
ATOM   1555  C CA    . TYR A 1 188 ? -66.720  -36.508  7.063   1.00 31.12  ? 188  TYR A CA    1 
ATOM   1556  C C     . TYR A 1 188 ? -66.265  -37.035  5.728   1.00 31.63  ? 188  TYR A C     1 
ATOM   1557  O O     . TYR A 1 188 ? -66.293  -36.357  4.749   1.00 28.19  ? 188  TYR A O     1 
ATOM   1558  C CB    . TYR A 1 188 ? -65.597  -35.692  7.656   1.00 34.23  ? 188  TYR A CB    1 
ATOM   1559  C CG    . TYR A 1 188 ? -66.026  -34.848  8.786   1.00 37.06  ? 188  TYR A CG    1 
ATOM   1560  C CD1   . TYR A 1 188 ? -66.755  -33.722  8.578   1.00 35.73  ? 188  TYR A CD1   1 
ATOM   1561  C CD2   . TYR A 1 188 ? -65.709  -35.182  10.057  1.00 34.73  ? 188  TYR A CD2   1 
ATOM   1562  C CE1   . TYR A 1 188 ? -67.152  -32.951  9.617   1.00 37.59  ? 188  TYR A CE1   1 
ATOM   1563  C CE2   . TYR A 1 188 ? -66.104  -34.426  11.097  1.00 38.20  ? 188  TYR A CE2   1 
ATOM   1564  C CZ    . TYR A 1 188 ? -66.832  -33.311  10.859  1.00 38.24  ? 188  TYR A CZ    1 
ATOM   1565  O OH    . TYR A 1 188 ? -67.229  -32.553  11.876  1.00 45.39  ? 188  TYR A OH    1 
ATOM   1566  N N     . GLN A 1 189 ? -65.805  -38.257  5.734   1.00 30.54  ? 189  GLN A N     1 
ATOM   1567  C CA    . GLN A 1 189 ? -65.293  -38.895  4.564   1.00 30.47  ? 189  GLN A CA    1 
ATOM   1568  C C     . GLN A 1 189 ? -65.842  -40.286  4.469   1.00 31.74  ? 189  GLN A C     1 
ATOM   1569  O O     . GLN A 1 189 ? -65.143  -41.223  4.677   1.00 30.64  ? 189  GLN A O     1 
ATOM   1570  C CB    . GLN A 1 189 ? -63.776  -38.931  4.628   1.00 25.30  ? 189  GLN A CB    1 
ATOM   1571  C CG    . GLN A 1 189 ? -63.079  -37.599  4.640   1.00 26.23  ? 189  GLN A CG    1 
ATOM   1572  C CD    . GLN A 1 189 ? -63.017  -36.968  3.277   1.00 31.44  ? 189  GLN A CD    1 
ATOM   1573  O OE1   . GLN A 1 189 ? -63.054  -37.640  2.298   1.00 30.22  ? 189  GLN A OE1   1 
ATOM   1574  N NE2   . GLN A 1 189 ? -62.931  -35.687  3.230   1.00 25.98  ? 189  GLN A NE2   1 
ATOM   1575  N N     . PRO A 1 190 ? -67.106  -40.434  4.100   1.00 36.70  ? 190  PRO A N     1 
ATOM   1576  C CA    . PRO A 1 190 ? -67.696  -41.767  4.034   1.00 32.23  ? 190  PRO A CA    1 
ATOM   1577  C C     . PRO A 1 190 ? -67.030  -42.722  3.048   1.00 29.73  ? 190  PRO A C     1 
ATOM   1578  O O     . PRO A 1 190 ? -67.021  -43.893  3.272   1.00 27.85  ? 190  PRO A O     1 
ATOM   1579  C CB    . PRO A 1 190 ? -69.149  -41.482  3.697   1.00 28.81  ? 190  PRO A CB    1 
ATOM   1580  C CG    . PRO A 1 190 ? -69.156  -40.139  3.137   1.00 29.41  ? 190  PRO A CG    1 
ATOM   1581  C CD    . PRO A 1 190 ? -68.104  -39.399  3.850   1.00 29.53  ? 190  PRO A CD    1 
ATOM   1582  N N     . ASN A 1 191 ? -66.538  -42.204  1.951   1.00 26.62  ? 191  ASN A N     1 
ATOM   1583  C CA    . ASN A 1 191 ? -65.872  -42.989  0.956   1.00 31.64  ? 191  ASN A CA    1 
ATOM   1584  C C     . ASN A 1 191 ? -64.411  -43.287  1.095   1.00 26.39  ? 191  ASN A C     1 
ATOM   1585  O O     . ASN A 1 191 ? -63.872  -43.991  0.321   1.00 27.21  ? 191  ASN A O     1 
ATOM   1586  C CB    . ASN A 1 191 ? -66.100  -42.381  -0.383  1.00 35.27  ? 191  ASN A CB    1 
ATOM   1587  C CG    . ASN A 1 191 ? -67.057  -43.153  -1.154  1.00 51.41  ? 191  ASN A CG    1 
ATOM   1588  O OD1   . ASN A 1 191 ? -66.703  -44.144  -1.743  1.00 52.58  ? 191  ASN A OD1   1 
ATOM   1589  N ND2   . ASN A 1 191 ? -68.308  -42.753  -1.104  1.00 55.05  ? 191  ASN A ND2   1 
ATOM   1590  N N     . ALA A 1 192 ? -63.776  -42.713  2.076   1.00 23.90  ? 192  ALA A N     1 
ATOM   1591  C CA    . ALA A 1 192 ? -62.395  -42.931  2.288   1.00 23.24  ? 192  ALA A CA    1 
ATOM   1592  C C     . ALA A 1 192 ? -62.077  -44.348  2.662   1.00 26.07  ? 192  ALA A C     1 
ATOM   1593  O O     . ALA A 1 192 ? -62.796  -44.974  3.356   1.00 26.16  ? 192  ALA A O     1 
ATOM   1594  C CB    . ALA A 1 192 ? -61.894  -41.989  3.352   1.00 26.34  ? 192  ALA A CB    1 
ATOM   1595  N N     . ILE A 1 193 ? -60.967  -44.832  2.173   1.00 24.91  ? 193  ILE A N     1 
ATOM   1596  C CA    . ILE A 1 193 ? -60.487  -46.137  2.492   1.00 24.36  ? 193  ILE A CA    1 
ATOM   1597  C C     . ILE A 1 193 ? -59.636  -46.004  3.750   1.00 24.16  ? 193  ILE A C     1 
ATOM   1598  O O     . ILE A 1 193 ? -58.829  -45.152  3.839   1.00 29.01  ? 193  ILE A O     1 
ATOM   1599  C CB    . ILE A 1 193 ? -59.649  -46.721  1.341   1.00 23.59  ? 193  ILE A CB    1 
ATOM   1600  C CG1   . ILE A 1 193 ? -60.512  -47.183  0.182   1.00 25.21  ? 193  ILE A CG1   1 
ATOM   1601  C CG2   . ILE A 1 193 ? -58.837  -47.888  1.790   1.00 19.11  ? 193  ILE A CG2   1 
ATOM   1602  C CD1   . ILE A 1 193 ? -61.386  -48.356  0.478   1.00 27.50  ? 193  ILE A CD1   1 
ATOM   1603  N N     . ILE A 1 194 ? -59.884  -46.803  4.752   1.00 21.80  ? 194  ILE A N     1 
ATOM   1604  C CA    . ILE A 1 194 ? -59.078  -46.760  5.963   1.00 21.73  ? 194  ILE A CA    1 
ATOM   1605  C C     . ILE A 1 194 ? -58.147  -47.976  5.990   1.00 23.71  ? 194  ILE A C     1 
ATOM   1606  O O     . ILE A 1 194 ? -58.609  -49.126  6.059   1.00 24.77  ? 194  ILE A O     1 
ATOM   1607  C CB    . ILE A 1 194 ? -59.938  -46.703  7.231   1.00 23.37  ? 194  ILE A CB    1 
ATOM   1608  C CG1   . ILE A 1 194 ? -60.843  -45.453  7.286   1.00 25.08  ? 194  ILE A CG1   1 
ATOM   1609  C CG2   . ILE A 1 194 ? -59.060  -46.826  8.482   1.00 21.60  ? 194  ILE A CG2   1 
ATOM   1610  C CD1   . ILE A 1 194 ? -61.751  -45.411  8.520   1.00 20.99  ? 194  ILE A CD1   1 
ATOM   1611  N N     . VAL A 1 195 ? -56.835  -47.697  5.959   1.00 23.35  ? 195  VAL A N     1 
ATOM   1612  C CA    . VAL A 1 195 ? -55.812  -48.733  5.961   1.00 24.11  ? 195  VAL A CA    1 
ATOM   1613  C C     . VAL A 1 195 ? -55.138  -48.711  7.318   1.00 24.16  ? 195  VAL A C     1 
ATOM   1614  O O     . VAL A 1 195 ? -54.788  -47.644  7.811   1.00 25.49  ? 195  VAL A O     1 
ATOM   1615  C CB    . VAL A 1 195 ? -54.747  -48.517  4.861   1.00 23.57  ? 195  VAL A CB    1 
ATOM   1616  C CG1   . VAL A 1 195 ? -53.732  -49.653  4.831   1.00 20.08  ? 195  VAL A CG1   1 
ATOM   1617  C CG2   . VAL A 1 195 ? -55.379  -48.319  3.487   1.00 22.85  ? 195  VAL A CG2   1 
ATOM   1618  N N     . SER A 1 196 ? -54.838  -49.872  7.822   1.00 26.80  ? 196  SER A N     1 
ATOM   1619  C CA    . SER A 1 196 ? -54.124  -50.005  9.056   1.00 32.88  ? 196  SER A CA    1 
ATOM   1620  C C     . SER A 1 196 ? -52.942  -50.981  9.016   1.00 32.59  ? 196  SER A C     1 
ATOM   1621  O O     . SER A 1 196 ? -53.039  -52.059  8.543   1.00 29.63  ? 196  SER A O     1 
ATOM   1622  C CB    . SER A 1 196 ? -55.071  -50.392  10.173  1.00 35.90  ? 196  SER A CB    1 
ATOM   1623  O OG    . SER A 1 196 ? -54.421  -50.328  11.396  1.00 33.31  ? 196  SER A OG    1 
ATOM   1624  N N     . ASN A 1 197 ? -51.829  -50.524  9.557   1.00 33.12  ? 197  ASN A N     1 
ATOM   1625  C CA    . ASN A 1 197 ? -50.590  -51.250  9.766   1.00 35.66  ? 197  ASN A CA    1 
ATOM   1626  C C     . ASN A 1 197 ? -50.708  -52.288  10.855  1.00 40.13  ? 197  ASN A C     1 
ATOM   1627  O O     . ASN A 1 197 ? -49.945  -53.191  10.950  1.00 50.75  ? 197  ASN A O     1 
ATOM   1628  C CB    . ASN A 1 197 ? -49.520  -50.307  10.197  1.00 45.74  ? 197  ASN A CB    1 
ATOM   1629  C CG    . ASN A 1 197 ? -48.247  -50.512  9.449   1.00 48.80  ? 197  ASN A CG    1 
ATOM   1630  O OD1   . ASN A 1 197 ? -48.179  -51.308  8.544   1.00 46.90  ? 197  ASN A OD1   1 
ATOM   1631  N ND2   . ASN A 1 197 ? -47.235  -49.794  9.830   1.00 45.14  ? 197  ASN A ND2   1 
ATOM   1632  N N     . THR A 1 198 ? -51.625  -52.089  11.759  1.00 60.03  ? 198  THR A N     1 
ATOM   1633  C CA    . THR A 1 198 ? -51.879  -53.045  12.811  1.00 72.10  ? 198  THR A CA    1 
ATOM   1634  C C     . THR A 1 198 ? -53.349  -53.415  12.866  1.00 77.00  ? 198  THR A C     1 
ATOM   1635  O O     . THR A 1 198 ? -53.929  -53.441  13.924  1.00 81.08  ? 198  THR A O     1 
ATOM   1636  C CB    . THR A 1 198 ? -51.468  -52.521  14.184  1.00 77.13  ? 198  THR A CB    1 
ATOM   1637  O OG1   . THR A 1 198 ? -51.722  -51.124  14.262  1.00 88.89  ? 198  THR A OG1   1 
ATOM   1638  C CG2   . THR A 1 198 ? -50.044  -52.759  14.385  1.00 66.55  ? 198  THR A CG2   1 
ATOM   1639  N N     . GLY A 1 199 ? -53.950  -53.620  11.710  1.00 68.44  ? 199  GLY A N     1 
ATOM   1640  C CA    . GLY A 1 199 ? -55.351  -53.961  11.566  1.00 70.03  ? 199  GLY A CA    1 
ATOM   1641  C C     . GLY A 1 199 ? -55.811  -55.274  12.151  1.00 85.13  ? 199  GLY A C     1 
ATOM   1642  O O     . GLY A 1 199 ? -56.948  -55.393  12.545  1.00 80.79  ? 199  GLY A O     1 
ATOM   1643  N N     . LEU A 1 200 ? -54.972  -56.291  12.071  1.00 97.64  ? 200  LEU A N     1 
ATOM   1644  C CA    . LEU A 1 200 ? -55.235  -57.602  12.651  1.00 96.24  ? 200  LEU A CA    1 
ATOM   1645  C C     . LEU A 1 200 ? -54.872  -57.739  14.144  1.00 107.81 ? 200  LEU A C     1 
ATOM   1646  O O     . LEU A 1 200 ? -54.150  -56.925  14.704  1.00 85.55  ? 200  LEU A O     1 
ATOM   1647  C CB    . LEU A 1 200 ? -54.529  -58.682  11.854  1.00 89.69  ? 200  LEU A CB    1 
ATOM   1648  C CG    . LEU A 1 200 ? -55.090  -58.973  10.478  1.00 81.65  ? 200  LEU A CG    1 
ATOM   1649  C CD1   . LEU A 1 200 ? -54.536  -60.270  9.955   1.00 73.96  ? 200  LEU A CD1   1 
ATOM   1650  C CD2   . LEU A 1 200 ? -56.598  -59.040  10.544  1.00 84.47  ? 200  LEU A CD2   1 
ATOM   1651  N N     . LYS A 1 201 ? -55.414  -58.787  14.763  1.00 131.34 ? 201  LYS A N     1 
ATOM   1652  C CA    . LYS A 1 201 ? -55.205  -59.179  16.171  1.00 115.66 ? 201  LYS A CA    1 
ATOM   1653  C C     . LYS A 1 201 ? -55.880  -60.520  16.408  1.00 100.15 ? 201  LYS A C     1 
ATOM   1654  O O     . LYS A 1 201 ? -55.604  -61.204  17.389  1.00 86.70  ? 201  LYS A O     1 
ATOM   1655  C CB    . LYS A 1 201 ? -55.778  -58.158  17.136  1.00 111.40 ? 201  LYS A CB    1 
ATOM   1656  C CG    . LYS A 1 201 ? -57.092  -57.568  16.670  1.00 108.37 ? 201  LYS A CG    1 
ATOM   1657  C CD    . LYS A 1 201 ? -57.588  -56.501  17.609  1.00 102.45 ? 201  LYS A CD    1 
ATOM   1658  C CE    . LYS A 1 201 ? -58.386  -57.083  18.754  1.00 93.54  ? 201  LYS A CE    1 
ATOM   1659  N NZ    . LYS A 1 201 ? -59.560  -56.218  19.058  1.00 85.14  ? 201  LYS A NZ    1 
ATOM   1660  N N     . GLN A 1 205 ? -58.930  -61.605  13.355  1.00 83.64  ? 205  GLN A N     1 
ATOM   1661  C CA    . GLN A 1 205 ? -59.922  -60.580  13.783  1.00 98.77  ? 205  GLN A CA    1 
ATOM   1662  C C     . GLN A 1 205 ? -59.308  -59.176  13.690  1.00 89.34  ? 205  GLN A C     1 
ATOM   1663  O O     . GLN A 1 205 ? -58.196  -58.943  14.174  1.00 76.23  ? 205  GLN A O     1 
ATOM   1664  C CB    . GLN A 1 205 ? -60.373  -60.871  15.219  1.00 111.56 ? 205  GLN A CB    1 
ATOM   1665  C CG    . GLN A 1 205 ? -61.617  -60.102  15.661  1.00 121.27 ? 205  GLN A CG    1 
ATOM   1666  C CD    . GLN A 1 205 ? -61.500  -59.494  17.045  1.00 118.27 ? 205  GLN A CD    1 
ATOM   1667  O OE1   . GLN A 1 205 ? -60.453  -59.568  17.703  1.00 121.88 ? 205  GLN A OE1   1 
ATOM   1668  N NE2   . GLN A 1 205 ? -62.563  -58.829  17.474  1.00 95.71  ? 205  GLN A NE2   1 
ATOM   1669  N N     . VAL A 1 206 ? -60.056  -58.245  13.069  1.00 74.39  ? 206  VAL A N     1 
ATOM   1670  C CA    . VAL A 1 206 ? -59.621  -56.887  12.750  1.00 61.80  ? 206  VAL A CA    1 
ATOM   1671  C C     . VAL A 1 206 ? -59.709  -55.999  13.990  1.00 54.13  ? 206  VAL A C     1 
ATOM   1672  O O     . VAL A 1 206 ? -60.536  -56.219  14.884  1.00 49.95  ? 206  VAL A O     1 
ATOM   1673  C CB    . VAL A 1 206 ? -60.483  -56.302  11.606  1.00 59.01  ? 206  VAL A CB    1 
ATOM   1674  C CG1   . VAL A 1 206 ? -60.083  -56.875  10.259  1.00 54.37  ? 206  VAL A CG1   1 
ATOM   1675  C CG2   . VAL A 1 206 ? -61.979  -56.484  11.894  1.00 56.54  ? 206  VAL A CG2   1 
ATOM   1676  N N     . SER A 1 207 ? -58.905  -54.923  14.007  1.00 49.07  ? 207  SER A N     1 
ATOM   1677  C CA    . SER A 1 207 ? -58.844  -54.083  15.192  1.00 43.52  ? 207  SER A CA    1 
ATOM   1678  C C     . SER A 1 207 ? -60.042  -53.134  15.319  1.00 43.07  ? 207  SER A C     1 
ATOM   1679  O O     . SER A 1 207 ? -60.231  -52.567  16.396  1.00 44.23  ? 207  SER A O     1 
ATOM   1680  C CB    . SER A 1 207 ? -57.526  -53.371  15.282  1.00 50.12  ? 207  SER A CB    1 
ATOM   1681  O OG    . SER A 1 207 ? -57.464  -52.305  14.346  1.00 54.85  ? 207  SER A OG    1 
ATOM   1682  N N     . ASP A 1 208 ? -60.854  -52.982  14.247  1.00 36.18  ? 208  ASP A N     1 
ATOM   1683  C CA    . ASP A 1 208 ? -62.039  -52.150  14.301  1.00 31.49  ? 208  ASP A CA    1 
ATOM   1684  C C     . ASP A 1 208 ? -62.899  -52.402  13.069  1.00 33.93  ? 208  ASP A C     1 
ATOM   1685  O O     . ASP A 1 208 ? -62.366  -52.487  11.962  1.00 40.32  ? 208  ASP A O     1 
ATOM   1686  C CB    . ASP A 1 208 ? -61.718  -50.664  14.372  1.00 27.77  ? 208  ASP A CB    1 
ATOM   1687  C CG    . ASP A 1 208 ? -62.928  -49.789  14.692  1.00 39.58  ? 208  ASP A CG    1 
ATOM   1688  O OD1   . ASP A 1 208 ? -63.211  -49.592  15.900  1.00 38.82  ? 208  ASP A OD1   1 
ATOM   1689  O OD2   . ASP A 1 208 ? -63.652  -49.383  13.738  1.00 39.76  ? 208  ASP A OD2   1 
ATOM   1690  N N     . PRO A 1 209 ? -64.246  -52.475  13.200  1.00 36.00  ? 209  PRO A N     1 
ATOM   1691  C CA    . PRO A 1 209 ? -65.108  -52.729  12.035  1.00 29.81  ? 209  PRO A CA    1 
ATOM   1692  C C     . PRO A 1 209 ? -64.922  -51.728  10.881  1.00 30.83  ? 209  PRO A C     1 
ATOM   1693  O O     . PRO A 1 209 ? -65.213  -52.061  9.728   1.00 30.75  ? 209  PRO A O     1 
ATOM   1694  C CB    . PRO A 1 209 ? -66.531  -52.699  12.606  1.00 28.01  ? 209  PRO A CB    1 
ATOM   1695  C CG    . PRO A 1 209 ? -66.350  -52.759  14.137  1.00 29.61  ? 209  PRO A CG    1 
ATOM   1696  C CD    . PRO A 1 209 ? -64.981  -52.367  14.481  1.00 28.82  ? 209  PRO A CD    1 
ATOM   1697  N N     . GLU A 1 210 ? -64.421  -50.512  11.173  1.00 22.90  ? 210  GLU A N     1 
ATOM   1698  C CA    . GLU A 1 210 ? -64.350  -49.498  10.139  1.00 23.75  ? 210  GLU A CA    1 
ATOM   1699  C C     . GLU A 1 210 ? -63.111  -49.657  9.238   1.00 28.48  ? 210  GLU A C     1 
ATOM   1700  O O     . GLU A 1 210 ? -63.032  -49.002  8.178   1.00 27.78  ? 210  GLU A O     1 
ATOM   1701  C CB    . GLU A 1 210 ? -64.418  -48.077  10.701  1.00 23.66  ? 210  GLU A CB    1 
ATOM   1702  C CG    . GLU A 1 210 ? -65.833  -47.701  11.124  1.00 29.50  ? 210  GLU A CG    1 
ATOM   1703  C CD    . GLU A 1 210 ? -66.872  -47.751  10.012  1.00 37.57  ? 210  GLU A CD    1 
ATOM   1704  O OE1   . GLU A 1 210 ? -66.579  -47.759  8.795   1.00 31.53  ? 210  GLU A OE1   1 
ATOM   1705  O OE2   . GLU A 1 210 ? -68.045  -47.807  10.404  1.00 41.55  ? 210  GLU A OE2   1 
ATOM   1706  N N     . ILE A 1 211 ? -62.133  -50.487  9.655   1.00 24.54  ? 211  ILE A N     1 
ATOM   1707  C CA    . ILE A 1 211 ? -60.968  -50.739  8.821   1.00 26.91  ? 211  ILE A CA    1 
ATOM   1708  C C     . ILE A 1 211 ? -61.378  -51.422  7.509   1.00 26.41  ? 211  ILE A C     1 
ATOM   1709  O O     . ILE A 1 211 ? -62.176  -52.343  7.519   1.00 26.13  ? 211  ILE A O     1 
ATOM   1710  C CB    . ILE A 1 211 ? -59.927  -51.558  9.612   1.00 26.95  ? 211  ILE A CB    1 
ATOM   1711  C CG1   . ILE A 1 211 ? -59.159  -50.644  10.556  1.00 23.59  ? 211  ILE A CG1   1 
ATOM   1712  C CG2   . ILE A 1 211 ? -58.979  -52.288  8.657   1.00 22.96  ? 211  ILE A CG2   1 
ATOM   1713  C CD1   . ILE A 1 211 ? -58.587  -51.413  11.724  1.00 29.51  ? 211  ILE A CD1   1 
ATOM   1714  N N     . ASP A 1 212 ? -60.812  -50.963  6.378   1.00 28.71  ? 212  ASP A N     1 
ATOM   1715  C CA    . ASP A 1 212 ? -61.112  -51.487  5.050   1.00 24.77  ? 212  ASP A CA    1 
ATOM   1716  C C     . ASP A 1 212 ? -59.967  -52.364  4.517   1.00 23.84  ? 212  ASP A C     1 
ATOM   1717  O O     . ASP A 1 212 ? -60.197  -53.231  3.678   1.00 23.92  ? 212  ASP A O     1 
ATOM   1718  C CB    . ASP A 1 212 ? -61.357  -50.327  4.099   1.00 24.70  ? 212  ASP A CB    1 
ATOM   1719  C CG    . ASP A 1 212 ? -62.553  -49.447  4.453   1.00 28.74  ? 212  ASP A CG    1 
ATOM   1720  O OD1   . ASP A 1 212 ? -63.587  -50.001  4.918   1.00 26.70  ? 212  ASP A OD1   1 
ATOM   1721  O OD2   . ASP A 1 212 ? -62.469  -48.215  4.208   1.00 30.65  ? 212  ASP A OD2   1 
ATOM   1722  N N     . VAL A 1 213 ? -58.741  -52.028  4.855   1.00 19.48  ? 213  VAL A N     1 
ATOM   1723  C CA    . VAL A 1 213 ? -57.565  -52.722  4.386   1.00 19.89  ? 213  VAL A CA    1 
ATOM   1724  C C     . VAL A 1 213 ? -56.557  -52.983  5.486   1.00 21.15  ? 213  VAL A C     1 
ATOM   1725  O O     . VAL A 1 213 ? -56.289  -52.160  6.284   1.00 24.89  ? 213  VAL A O     1 
ATOM   1726  C CB    . VAL A 1 213 ? -56.831  -51.917  3.268   1.00 21.11  ? 213  VAL A CB    1 
ATOM   1727  C CG1   . VAL A 1 213 ? -55.726  -52.702  2.588   1.00 16.91  ? 213  VAL A CG1   1 
ATOM   1728  C CG2   . VAL A 1 213 ? -57.779  -51.399  2.232   1.00 17.62  ? 213  VAL A CG2   1 
ATOM   1729  N N     . VAL A 1 214 ? -55.960  -54.143  5.462   1.00 22.44  ? 214  VAL A N     1 
ATOM   1730  C CA    . VAL A 1 214 ? -54.949  -54.525  6.379   1.00 25.31  ? 214  VAL A CA    1 
ATOM   1731  C C     . VAL A 1 214 ? -53.649  -54.755  5.610   1.00 26.44  ? 214  VAL A C     1 
ATOM   1732  O O     . VAL A 1 214 ? -53.676  -55.194  4.507   1.00 23.32  ? 214  VAL A O     1 
ATOM   1733  C CB    . VAL A 1 214 ? -55.407  -55.777  7.119   1.00 32.12  ? 214  VAL A CB    1 
ATOM   1734  C CG1   . VAL A 1 214 ? -54.296  -56.416  7.884   1.00 42.14  ? 214  VAL A CG1   1 
ATOM   1735  C CG2   . VAL A 1 214 ? -56.490  -55.409  8.078   1.00 32.32  ? 214  VAL A CG2   1 
ATOM   1736  N N     . THR A 1 215 ? -52.530  -54.324  6.153   1.00 25.22  ? 215  THR A N     1 
ATOM   1737  C CA    . THR A 1 215 ? -51.226  -54.571  5.546   1.00 30.49  ? 215  THR A CA    1 
ATOM   1738  C C     . THR A 1 215 ? -50.564  -55.932  5.872   1.00 43.92  ? 215  THR A C     1 
ATOM   1739  O O     . THR A 1 215 ? -50.795  -56.509  6.899   1.00 49.66  ? 215  THR A O     1 
ATOM   1740  C CB    . THR A 1 215 ? -50.238  -53.485  5.866   1.00 31.45  ? 215  THR A CB    1 
ATOM   1741  O OG1   . THR A 1 215 ? -49.929  -53.534  7.238   1.00 26.96  ? 215  THR A OG1   1 
ATOM   1742  C CG2   . THR A 1 215 ? -50.775  -52.150  5.487   1.00 25.96  ? 215  THR A CG2   1 
ATOM   1743  N N     . TYR A 1 216 ? -49.727  -56.432  4.979   1.00 45.07  ? 216  TYR A N     1 
ATOM   1744  C CA    . TYR A 1 216 ? -49.074  -57.721  5.137   1.00 43.68  ? 216  TYR A CA    1 
ATOM   1745  C C     . TYR A 1 216 ? -47.638  -57.703  4.660   1.00 55.39  ? 216  TYR A C     1 
ATOM   1746  O O     . TYR A 1 216 ? -47.243  -56.797  3.952   1.00 53.24  ? 216  TYR A O     1 
ATOM   1747  C CB    . TYR A 1 216 ? -49.779  -58.773  4.317   1.00 42.57  ? 216  TYR A CB    1 
ATOM   1748  C CG    . TYR A 1 216 ? -51.185  -59.073  4.690   1.00 50.63  ? 216  TYR A CG    1 
ATOM   1749  C CD1   . TYR A 1 216 ? -52.222  -58.359  4.172   1.00 43.90  ? 216  TYR A CD1   1 
ATOM   1750  C CD2   . TYR A 1 216 ? -51.477  -60.116  5.523   1.00 54.39  ? 216  TYR A CD2   1 
ATOM   1751  C CE1   . TYR A 1 216 ? -53.509  -58.658  4.503   1.00 50.71  ? 216  TYR A CE1   1 
ATOM   1752  C CE2   . TYR A 1 216 ? -52.761  -60.420  5.855   1.00 56.57  ? 216  TYR A CE2   1 
ATOM   1753  C CZ    . TYR A 1 216 ? -53.766  -59.682  5.344   1.00 54.90  ? 216  TYR A CZ    1 
ATOM   1754  O OH    . TYR A 1 216 ? -55.025  -59.987  5.678   1.00 59.20  ? 216  TYR A OH    1 
ATOM   1755  N N     . GLU A 1 217 ? -46.875  -58.718  5.079   1.00 65.37  ? 217  GLU A N     1 
ATOM   1756  C CA    . GLU A 1 217 ? -45.467  -58.941  4.735   1.00 56.47  ? 217  GLU A CA    1 
ATOM   1757  C C     . GLU A 1 217 ? -45.372  -59.197  3.261   1.00 48.90  ? 217  GLU A C     1 
ATOM   1758  O O     . GLU A 1 217 ? -46.185  -59.871  2.729   1.00 51.51  ? 217  GLU A O     1 
ATOM   1759  C CB    . GLU A 1 217 ? -44.938  -60.148  5.492   1.00 59.87  ? 217  GLU A CB    1 
ATOM   1760  C CG    . GLU A 1 217 ? -44.467  -59.829  6.886   1.00 87.54  ? 217  GLU A CG    1 
ATOM   1761  C CD    . GLU A 1 217 ? -44.250  -61.054  7.768   1.00 111.65 ? 217  GLU A CD    1 
ATOM   1762  O OE1   . GLU A 1 217 ? -44.690  -62.168  7.421   1.00 125.70 ? 217  GLU A OE1   1 
ATOM   1763  O OE2   . GLU A 1 217 ? -43.636  -60.908  8.837   1.00 111.95 ? 217  GLU A OE2   1 
ATOM   1764  N N     . ARG A 1 218 ? -44.348  -58.708  2.603   1.00 43.78  ? 218  ARG A N     1 
ATOM   1765  C CA    . ARG A 1 218 ? -44.319  -58.844  1.152   1.00 49.08  ? 218  ARG A CA    1 
ATOM   1766  C C     . ARG A 1 218 ? -44.116  -60.307  0.754   1.00 53.38  ? 218  ARG A C     1 
ATOM   1767  O O     . ARG A 1 218 ? -44.513  -60.721  -0.331  1.00 51.15  ? 218  ARG A O     1 
ATOM   1768  C CB    . ARG A 1 218 ? -43.390  -57.854  0.444   1.00 45.86  ? 218  ARG A CB    1 
ATOM   1769  C CG    . ARG A 1 218 ? -41.913  -58.084  0.664   1.00 54.60  ? 218  ARG A CG    1 
ATOM   1770  C CD    . ARG A 1 218 ? -41.135  -56.847  0.286   1.00 56.13  ? 218  ARG A CD    1 
ATOM   1771  N NE    . ARG A 1 218 ? -39.858  -56.904  1.002   1.00 54.59  ? 218  ARG A NE    1 
ATOM   1772  C CZ    . ARG A 1 218 ? -38.825  -57.605  0.535   1.00 65.46  ? 218  ARG A CZ    1 
ATOM   1773  N NH1   . ARG A 1 218 ? -38.905  -58.186  -0.677  1.00 54.87  ? 218  ARG A NH1   1 
ATOM   1774  N NH2   . ARG A 1 218 ? -37.715  -57.677  1.272   1.00 59.29  ? 218  ARG A NH2   1 
ATOM   1775  N N     . ARG A 1 219 ? -43.586  -61.097  1.689   1.00 61.46  ? 219  ARG A N     1 
ATOM   1776  C CA    . ARG A 1 219 ? -43.244  -62.482  1.413   1.00 62.68  ? 219  ARG A CA    1 
ATOM   1777  C C     . ARG A 1 219 ? -44.418  -63.420  1.718   1.00 57.40  ? 219  ARG A C     1 
ATOM   1778  O O     . ARG A 1 219 ? -44.259  -64.630  1.545   1.00 56.83  ? 219  ARG A O     1 
ATOM   1779  C CB    . ARG A 1 219 ? -41.935  -62.917  2.089   1.00 71.94  ? 219  ARG A CB    1 
ATOM   1780  C CG    . ARG A 1 219 ? -40.712  -62.069  1.774   1.00 90.24  ? 219  ARG A CG    1 
ATOM   1781  C CD    . ARG A 1 219 ? -39.343  -62.693  1.644   1.00 93.97  ? 219  ARG A CD    1 
ATOM   1782  N NE    . ARG A 1 219 ? -38.290  -61.747  2.041   1.00 96.15  ? 219  ARG A NE    1 
ATOM   1783  C CZ    . ARG A 1 219 ? -37.235  -61.333  1.317   1.00 99.31  ? 219  ARG A CZ    1 
ATOM   1784  N NH1   . ARG A 1 219 ? -37.100  -61.709  0.049   1.00 76.78  ? 219  ARG A NH1   1 
ATOM   1785  N NH2   . ARG A 1 219 ? -36.300  -60.600  1.900   1.00 94.25  ? 219  ARG A NH2   1 
ATOM   1786  N N     . THR A 1 220 ? -45.589  -62.897  2.149   1.00 46.03  ? 220  THR A N     1 
ATOM   1787  C CA    . THR A 1 220 ? -46.741  -63.749  2.423   1.00 52.35  ? 220  THR A CA    1 
ATOM   1788  C C     . THR A 1 220 ? -46.901  -64.756  1.279   1.00 53.63  ? 220  THR A C     1 
ATOM   1789  O O     . THR A 1 220 ? -47.067  -64.350  0.127   1.00 48.73  ? 220  THR A O     1 
ATOM   1790  C CB    . THR A 1 220 ? -48.026  -62.943  2.620   1.00 49.62  ? 220  THR A CB    1 
ATOM   1791  O OG1   . THR A 1 220 ? -47.778  -61.966  3.624   1.00 45.15  ? 220  THR A OG1   1 
ATOM   1792  C CG2   . THR A 1 220 ? -49.189  -63.828  3.035   1.00 46.06  ? 220  THR A CG2   1 
ATOM   1793  N N     . PRO A 1 221 ? -46.862  -66.092  1.537   1.00 64.20  ? 221  PRO A N     1 
ATOM   1794  C CA    . PRO A 1 221 ? -46.869  -67.073  0.445   1.00 63.98  ? 221  PRO A CA    1 
ATOM   1795  C C     . PRO A 1 221 ? -48.232  -67.272  -0.230  1.00 64.79  ? 221  PRO A C     1 
ATOM   1796  O O     . PRO A 1 221 ? -48.295  -67.495  -1.440  1.00 56.73  ? 221  PRO A O     1 
ATOM   1797  C CB    . PRO A 1 221 ? -46.262  -68.350  1.064   1.00 58.24  ? 221  PRO A CB    1 
ATOM   1798  C CG    . PRO A 1 221 ? -46.466  -68.166  2.571   1.00 57.98  ? 221  PRO A CG    1 
ATOM   1799  C CD    . PRO A 1 221 ? -46.785  -66.717  2.878   1.00 66.39  ? 221  PRO A CD    1 
ATOM   1800  N N     . ASP A 1 222 ? -49.325  -67.172  0.555   1.00 68.81  ? 222  ASP A N     1 
ATOM   1801  C CA    . ASP A 1 222 ? -50.638  -67.600  0.092   1.00 80.60  ? 222  ASP A CA    1 
ATOM   1802  C C     . ASP A 1 222 ? -51.589  -66.414  0.035   1.00 69.14  ? 222  ASP A C     1 
ATOM   1803  O O     . ASP A 1 222 ? -51.333  -65.398  0.682   1.00 75.16  ? 222  ASP A O     1 
ATOM   1804  C CB    . ASP A 1 222 ? -51.273  -68.618  1.026   1.00 95.31  ? 222  ASP A CB    1 
ATOM   1805  C CG    . ASP A 1 222 ? -50.423  -69.829  1.382   1.00 103.24 ? 222  ASP A CG    1 
ATOM   1806  O OD1   . ASP A 1 222 ? -50.055  -70.593  0.445   1.00 89.55  ? 222  ASP A OD1   1 
ATOM   1807  O OD2   . ASP A 1 222 ? -50.135  -69.984  2.590   1.00 89.53  ? 222  ASP A OD2   1 
ATOM   1808  N N     . GLU A 1 223 ? -52.704  -66.602  -0.694  1.00 58.05  ? 223  GLU A N     1 
ATOM   1809  C CA    . GLU A 1 223 ? -53.802  -65.642  -0.760  1.00 57.42  ? 223  GLU A CA    1 
ATOM   1810  C C     . GLU A 1 223 ? -54.142  -65.105  0.639   1.00 57.92  ? 223  GLU A C     1 
ATOM   1811  O O     . GLU A 1 223 ? -54.205  -65.867  1.608   1.00 67.24  ? 223  GLU A O     1 
ATOM   1812  C CB    . GLU A 1 223 ? -54.992  -66.301  -1.457  1.00 62.67  ? 223  GLU A CB    1 
ATOM   1813  C CG    . GLU A 1 223 ? -56.150  -65.320  -1.640  1.00 81.71  ? 223  GLU A CG    1 
ATOM   1814  C CD    . GLU A 1 223 ? -57.246  -65.758  -2.593  1.00 79.51  ? 223  GLU A CD    1 
ATOM   1815  O OE1   . GLU A 1 223 ? -57.165  -66.893  -3.111  1.00 79.38  ? 223  GLU A OE1   1 
ATOM   1816  O OE2   . GLU A 1 223 ? -58.185  -64.959  -2.779  1.00 70.57  ? 223  GLU A OE2   1 
ATOM   1817  N N     . ILE A 1 224 ? -54.327  -63.781  0.758   1.00 52.36  ? 224  ILE A N     1 
ATOM   1818  C CA    . ILE A 1 224 ? -54.423  -63.131  2.062   1.00 49.78  ? 224  ILE A CA    1 
ATOM   1819  C C     . ILE A 1 224 ? -55.812  -63.384  2.678   1.00 54.10  ? 224  ILE A C     1 
ATOM   1820  O O     . ILE A 1 224 ? -56.729  -63.864  2.001   1.00 44.47  ? 224  ILE A O     1 
ATOM   1821  C CB    . ILE A 1 224 ? -54.154  -61.622  1.932   1.00 44.52  ? 224  ILE A CB    1 
ATOM   1822  C CG1   . ILE A 1 224 ? -55.120  -61.027  0.949   1.00 42.73  ? 224  ILE A CG1   1 
ATOM   1823  C CG2   . ILE A 1 224 ? -52.713  -61.297  1.539   1.00 42.50  ? 224  ILE A CG2   1 
ATOM   1824  C CD1   . ILE A 1 224 ? -55.547  -59.634  1.317   1.00 53.93  ? 224  ILE A CD1   1 
ATOM   1825  N N     . TYR A 1 225 ? -55.958  -63.010  3.959   1.00 55.41  ? 225  TYR A N     1 
ATOM   1826  C CA    . TYR A 1 225 ? -57.177  -63.202  4.739   1.00 64.26  ? 225  TYR A CA    1 
ATOM   1827  C C     . TYR A 1 225 ? -58.160  -62.039  4.536   1.00 55.02  ? 225  TYR A C     1 
ATOM   1828  O O     . TYR A 1 225 ? -57.793  -60.876  4.672   1.00 56.12  ? 225  TYR A O     1 
ATOM   1829  C CB    . TYR A 1 225 ? -56.686  -63.278  6.192   1.00 71.54  ? 225  TYR A CB    1 
ATOM   1830  C CG    . TYR A 1 225 ? -57.790  -63.282  7.244   1.00 97.30  ? 225  TYR A CG    1 
ATOM   1831  C CD1   . TYR A 1 225 ? -58.705  -64.343  7.325   1.00 88.60  ? 225  TYR A CD1   1 
ATOM   1832  C CD2   . TYR A 1 225 ? -57.918  -62.222  8.151   1.00 101.66 ? 225  TYR A CD2   1 
ATOM   1833  C CE1   . TYR A 1 225 ? -59.708  -64.343  8.282   1.00 89.19  ? 225  TYR A CE1   1 
ATOM   1834  C CE2   . TYR A 1 225 ? -58.927  -62.208  9.102   1.00 105.12 ? 225  TYR A CE2   1 
ATOM   1835  C CZ    . TYR A 1 225 ? -59.814  -63.275  9.170   1.00 108.41 ? 225  TYR A CZ    1 
ATOM   1836  O OH    . TYR A 1 225 ? -60.806  -63.242  10.114  1.00 111.94 ? 225  TYR A OH    1 
ATOM   1837  N N     . HIS A 1 226 ? -59.436  -62.340  4.281   1.00 49.23  ? 226  HIS A N     1 
ATOM   1838  C CA    . HIS A 1 226 ? -60.398  -61.296  3.958   1.00 41.88  ? 226  HIS A CA    1 
ATOM   1839  C C     . HIS A 1 226 ? -61.429  -61.011  5.059   1.00 42.45  ? 226  HIS A C     1 
ATOM   1840  O O     . HIS A 1 226 ? -62.363  -60.238  4.821   1.00 37.60  ? 226  HIS A O     1 
ATOM   1841  C CB    . HIS A 1 226 ? -61.038  -61.569  2.598   1.00 38.55  ? 226  HIS A CB    1 
ATOM   1842  C CG    . HIS A 1 226 ? -60.061  -61.448  1.484   1.00 46.97  ? 226  HIS A CG    1 
ATOM   1843  N ND1   . HIS A 1 226 ? -59.338  -60.295  1.266   1.00 43.87  ? 226  HIS A ND1   1 
ATOM   1844  C CD2   . HIS A 1 226 ? -59.713  -62.305  0.518   1.00 47.29  ? 226  HIS A CD2   1 
ATOM   1845  C CE1   . HIS A 1 226 ? -58.555  -60.471  0.209   1.00 49.85  ? 226  HIS A CE1   1 
ATOM   1846  N NE2   . HIS A 1 226 ? -58.764  -61.683  -0.260  1.00 55.65  ? 226  HIS A NE2   1 
ATOM   1847  N N     . GLY A 1 227 ? -61.256  -61.587  6.264   1.00 51.40  ? 227  GLY A N     1 
ATOM   1848  C CA    . GLY A 1 227 ? -62.214  -61.475  7.363   1.00 58.21  ? 227  GLY A CA    1 
ATOM   1849  C C     . GLY A 1 227 ? -62.996  -62.778  7.609   1.00 63.52  ? 227  GLY A C     1 
ATOM   1850  O O     . GLY A 1 227 ? -63.057  -63.647  6.722   1.00 52.55  ? 227  GLY A O     1 
ATOM   1851  N N     . ALA A 1 228 ? -63.607  -62.893  8.810   1.00 75.18  ? 228  ALA A N     1 
ATOM   1852  C CA    . ALA A 1 228 ? -64.434  -64.043  9.179   1.00 89.82  ? 228  ALA A CA    1 
ATOM   1853  C C     . ALA A 1 228 ? -65.662  -64.111  8.272   1.00 89.40  ? 228  ALA A C     1 
ATOM   1854  O O     . ALA A 1 228 ? -66.113  -63.070  7.811   1.00 94.28  ? 228  ALA A O     1 
ATOM   1855  C CB    . ALA A 1 228 ? -64.824  -63.955  10.638  1.00 85.39  ? 228  ALA A CB    1 
ATOM   1856  N N     . PRO A 1 229 ? -66.241  -65.300  7.948   1.00 90.99  ? 229  PRO A N     1 
ATOM   1857  C CA    . PRO A 1 229 ? -67.396  -65.330  7.043   1.00 90.80  ? 229  PRO A CA    1 
ATOM   1858  C C     . PRO A 1 229 ? -68.643  -64.698  7.676   1.00 86.91  ? 229  PRO A C     1 
ATOM   1859  O O     . PRO A 1 229 ? -68.851  -64.785  8.893   1.00 76.71  ? 229  PRO A O     1 
ATOM   1860  C CB    . PRO A 1 229 ? -67.476  -66.774  6.538   1.00 83.52  ? 229  PRO A CB    1 
ATOM   1861  C CG    . PRO A 1 229 ? -66.602  -67.562  7.523   1.00 86.61  ? 229  PRO A CG    1 
ATOM   1862  C CD    . PRO A 1 229 ? -65.830  -66.629  8.440   1.00 82.26  ? 229  PRO A CD    1 
ATOM   1863  N N     . ASN A 1 230 ? -69.439  -63.982  6.869   1.00 77.85  ? 230  ASN A N     1 
ATOM   1864  C CA    . ASN A 1 230 ? -70.541  -63.174  7.385   1.00 80.61  ? 230  ASN A CA    1 
ATOM   1865  C C     . ASN A 1 230 ? -70.083  -61.868  8.051   1.00 73.26  ? 230  ASN A C     1 
ATOM   1866  O O     . ASN A 1 230 ? -70.926  -61.086  8.463   1.00 71.01  ? 230  ASN A O     1 
ATOM   1867  C CB    . ASN A 1 230 ? -71.508  -63.978  8.246   1.00 89.45  ? 230  ASN A CB    1 
ATOM   1868  C CG    . ASN A 1 230 ? -72.529  -64.699  7.400   1.00 98.98  ? 230  ASN A CG    1 
ATOM   1869  O OD1   . ASN A 1 230 ? -73.720  -64.617  7.705   1.00 94.39  ? 230  ASN A OD1   1 
ATOM   1870  N ND2   . ASN A 1 230 ? -72.106  -65.381  6.340   1.00 106.48 ? 230  ASN A ND2   1 
ATOM   1871  N N     . GLU A 1 231 ? -68.769  -61.593  8.059   1.00 58.32  ? 231  GLU A N     1 
ATOM   1872  C CA    . GLU A 1 231 ? -68.273  -60.277  8.436   1.00 49.16  ? 231  GLU A CA    1 
ATOM   1873  C C     . GLU A 1 231 ? -67.863  -59.465  7.203   1.00 35.82  ? 231  GLU A C     1 
ATOM   1874  O O     . GLU A 1 231 ? -67.863  -59.968  6.096   1.00 31.76  ? 231  GLU A O     1 
ATOM   1875  C CB    . GLU A 1 231 ? -67.238  -60.389  9.546   1.00 61.03  ? 231  GLU A CB    1 
ATOM   1876  C CG    . GLU A 1 231 ? -67.833  -61.093  10.761  1.00 86.96  ? 231  GLU A CG    1 
ATOM   1877  C CD    . GLU A 1 231 ? -67.030  -60.881  12.032  1.00 90.40  ? 231  GLU A CD    1 
ATOM   1878  O OE1   . GLU A 1 231 ? -67.554  -61.252  13.101  1.00 88.63  ? 231  GLU A OE1   1 
ATOM   1879  O OE2   . GLU A 1 231 ? -65.901  -60.341  11.964  1.00 73.73  ? 231  GLU A OE2   1 
ATOM   1880  N N     . LYS A 1 232 ? -67.588  -58.171  7.418   1.00 32.12  ? 232  LYS A N     1 
ATOM   1881  C CA    . LYS A 1 232 ? -67.178  -57.263  6.359   1.00 28.01  ? 232  LYS A CA    1 
ATOM   1882  C C     . LYS A 1 232 ? -65.889  -57.798  5.728   1.00 29.10  ? 232  LYS A C     1 
ATOM   1883  O O     . LYS A 1 232 ? -64.951  -58.218  6.430   1.00 29.66  ? 232  LYS A O     1 
ATOM   1884  C CB    . LYS A 1 232 ? -66.911  -55.911  7.019   1.00 25.22  ? 232  LYS A CB    1 
ATOM   1885  C CG    . LYS A 1 232 ? -66.563  -54.776  6.066   1.00 26.48  ? 232  LYS A CG    1 
ATOM   1886  C CD    . LYS A 1 232 ? -65.931  -53.631  6.844   1.00 30.22  ? 232  LYS A CD    1 
ATOM   1887  C CE    . LYS A 1 232 ? -65.379  -52.579  5.967   1.00 30.39  ? 232  LYS A CE    1 
ATOM   1888  N NZ    . LYS A 1 232 ? -64.756  -51.512  6.752   1.00 26.28  ? 232  LYS A NZ    1 
ATOM   1889  N N     . TYR A 1 233 ? -65.871  -57.811  4.391   1.00 23.71  ? 233  TYR A N     1 
ATOM   1890  C CA    . TYR A 1 233 ? -64.669  -58.147  3.654   1.00 25.71  ? 233  TYR A CA    1 
ATOM   1891  C C     . TYR A 1 233 ? -63.617  -57.041  3.797   1.00 28.55  ? 233  TYR A C     1 
ATOM   1892  O O     . TYR A 1 233 ? -63.886  -55.857  3.543   1.00 28.04  ? 233  TYR A O     1 
ATOM   1893  C CB    . TYR A 1 233 ? -65.101  -58.197  2.193   1.00 24.72  ? 233  TYR A CB    1 
ATOM   1894  C CG    . TYR A 1 233 ? -63.964  -58.528  1.231   1.00 31.83  ? 233  TYR A CG    1 
ATOM   1895  C CD1   . TYR A 1 233 ? -63.108  -57.525  0.760   1.00 27.40  ? 233  TYR A CD1   1 
ATOM   1896  C CD2   . TYR A 1 233 ? -63.775  -59.838  0.767   1.00 26.68  ? 233  TYR A CD2   1 
ATOM   1897  C CE1   . TYR A 1 233 ? -62.106  -57.820  -0.151  1.00 29.14  ? 233  TYR A CE1   1 
ATOM   1898  C CE2   . TYR A 1 233 ? -62.800  -60.130  -0.170  1.00 27.26  ? 233  TYR A CE2   1 
ATOM   1899  C CZ    . TYR A 1 233 ? -61.959  -59.121  -0.627  1.00 29.95  ? 233  TYR A CZ    1 
ATOM   1900  O OH    . TYR A 1 233 ? -60.976  -59.412  -1.541  1.00 24.99  ? 233  TYR A OH    1 
ATOM   1901  N N     . VAL A 1 234 ? -62.394  -57.449  4.149   1.00 28.09  ? 234  VAL A N     1 
ATOM   1902  C CA    . VAL A 1 234 ? -61.271  -56.529  4.288   1.00 28.56  ? 234  VAL A CA    1 
ATOM   1903  C C     . VAL A 1 234 ? -60.223  -56.859  3.231   1.00 23.80  ? 234  VAL A C     1 
ATOM   1904  O O     . VAL A 1 234 ? -59.853  -58.021  3.075   1.00 23.06  ? 234  VAL A O     1 
ATOM   1905  C CB    . VAL A 1 234 ? -60.737  -56.708  5.723   1.00 29.08  ? 234  VAL A CB    1 
ATOM   1906  C CG1   . VAL A 1 234 ? -59.506  -55.872  5.976   1.00 27.85  ? 234  VAL A CG1   1 
ATOM   1907  C CG2   . VAL A 1 234 ? -61.796  -56.267  6.710   1.00 26.60  ? 234  VAL A CG2   1 
ATOM   1908  N N     . ALA A 1 235 ? -59.775  -55.835  2.496   1.00 19.20  ? 235  ALA A N     1 
ATOM   1909  C CA    . ALA A 1 235 ? -58.735  -56.028  1.491   1.00 20.08  ? 235  ALA A CA    1 
ATOM   1910  C C     . ALA A 1 235 ? -57.350  -56.115  2.161   1.00 22.88  ? 235  ALA A C     1 
ATOM   1911  O O     . ALA A 1 235 ? -57.221  -55.940  3.378   1.00 23.85  ? 235  ALA A O     1 
ATOM   1912  C CB    . ALA A 1 235 ? -58.801  -54.902  0.493   1.00 19.30  ? 235  ALA A CB    1 
ATOM   1913  N N     . GLY A 1 236 ? -56.308  -56.355  1.356   1.00 21.55  ? 236  GLY A N     1 
ATOM   1914  C CA    . GLY A 1 236 ? -54.938  -56.428  1.840   1.00 22.39  ? 236  GLY A CA    1 
ATOM   1915  C C     . GLY A 1 236 ? -53.963  -55.649  0.954   1.00 23.65  ? 236  GLY A C     1 
ATOM   1916  O O     . GLY A 1 236 ? -54.247  -55.371  -0.215  1.00 24.10  ? 236  GLY A O     1 
ATOM   1917  N N     . GLU A 1 237 ? -52.812  -55.279  1.536   1.00 23.89  ? 237  GLU A N     1 
ATOM   1918  C CA    . GLU A 1 237 ? -51.817  -54.500  0.804   1.00 21.44  ? 237  GLU A CA    1 
ATOM   1919  C C     . GLU A 1 237 ? -50.435  -54.912  1.298   1.00 21.99  ? 237  GLU A C     1 
ATOM   1920  O O     . GLU A 1 237 ? -50.250  -55.146  2.491   1.00 21.47  ? 237  GLU A O     1 
ATOM   1921  C CB    . GLU A 1 237 ? -52.046  -53.027  1.130   1.00 20.82  ? 237  GLU A CB    1 
ATOM   1922  C CG    . GLU A 1 237 ? -51.291  -52.063  0.215   1.00 26.61  ? 237  GLU A CG    1 
ATOM   1923  C CD    . GLU A 1 237 ? -51.468  -50.605  0.710   1.00 30.08  ? 237  GLU A CD    1 
ATOM   1924  O OE1   . GLU A 1 237 ? -52.164  -49.767  0.056   1.00 28.41  ? 237  GLU A OE1   1 
ATOM   1925  O OE2   . GLU A 1 237 ? -50.898  -50.301  1.794   1.00 29.65  ? 237  GLU A OE2   1 
ATOM   1926  N N     . ILE A 1 238 ? -49.478  -55.033  0.371   1.00 22.78  ? 238  ILE A N     1 
ATOM   1927  C CA    . ILE A 1 238 ? -48.085  -55.190  0.745   1.00 22.66  ? 238  ILE A CA    1 
ATOM   1928  C C     . ILE A 1 238 ? -47.304  -53.962  0.277   1.00 23.87  ? 238  ILE A C     1 
ATOM   1929  O O     . ILE A 1 238 ? -47.769  -53.200  -0.560  1.00 24.07  ? 238  ILE A O     1 
ATOM   1930  C CB    . ILE A 1 238 ? -47.499  -56.523  0.236   1.00 22.92  ? 238  ILE A CB    1 
ATOM   1931  C CG1   . ILE A 1 238 ? -47.318  -56.536  -1.243  1.00 26.46  ? 238  ILE A CG1   1 
ATOM   1932  C CG2   . ILE A 1 238 ? -48.325  -57.729  0.696   1.00 22.59  ? 238  ILE A CG2   1 
ATOM   1933  C CD1   . ILE A 1 238 ? -46.771  -57.868  -1.756  1.00 27.38  ? 238  ILE A CD1   1 
ATOM   1934  N N     . SER A 1 239 ? -46.084  -53.815  0.796   1.00 24.18  ? 239  SER A N     1 
ATOM   1935  C CA    . SER A 1 239 ? -45.225  -52.656  0.627   1.00 25.98  ? 239  SER A CA    1 
ATOM   1936  C C     . SER A 1 239 ? -43.824  -53.118  0.272   1.00 24.54  ? 239  SER A C     1 
ATOM   1937  O O     . SER A 1 239 ? -43.356  -54.087  0.833   1.00 24.25  ? 239  SER A O     1 
ATOM   1938  C CB    . SER A 1 239 ? -45.152  -51.899  1.930   1.00 28.10  ? 239  SER A CB    1 
ATOM   1939  O OG    . SER A 1 239 ? -46.249  -51.003  1.921   1.00 38.30  ? 239  SER A OG    1 
ATOM   1940  N N     . ILE A 1 240 ? -43.135  -52.377  -0.587  1.00 25.21  ? 240  ILE A N     1 
ATOM   1941  C CA    . ILE A 1 240 ? -41.731  -52.655  -0.820  1.00 25.22  ? 240  ILE A CA    1 
ATOM   1942  C C     . ILE A 1 240 ? -41.006  -51.317  -0.832  1.00 25.36  ? 240  ILE A C     1 
ATOM   1943  O O     . ILE A 1 240 ? -41.467  -50.364  -1.464  1.00 25.75  ? 240  ILE A O     1 
ATOM   1944  C CB    . ILE A 1 240 ? -41.513  -53.504  -2.093  1.00 28.83  ? 240  ILE A CB    1 
ATOM   1945  C CG1   . ILE A 1 240 ? -40.058  -53.933  -2.232  1.00 36.98  ? 240  ILE A CG1   1 
ATOM   1946  C CG2   . ILE A 1 240 ? -41.978  -52.803  -3.370  1.00 22.92  ? 240  ILE A CG2   1 
ATOM   1947  C CD1   . ILE A 1 240 ? -39.773  -54.788  -3.467  1.00 37.82  ? 240  ILE A CD1   1 
ATOM   1948  N N     . THR A 1 241 ? -39.880  -51.254  -0.115  1.00 22.89  ? 241  THR A N     1 
ATOM   1949  C CA    . THR A 1 241 ? -39.006  -50.100  -0.262  1.00 21.55  ? 241  THR A CA    1 
ATOM   1950  C C     . THR A 1 241 ? -37.782  -50.531  -1.080  1.00 20.04  ? 241  THR A C     1 
ATOM   1951  O O     . THR A 1 241 ? -37.453  -51.710  -1.117  1.00 20.40  ? 241  THR A O     1 
ATOM   1952  C CB    . THR A 1 241 ? -38.689  -49.498  1.121   1.00 22.95  ? 241  THR A CB    1 
ATOM   1953  O OG1   . THR A 1 241 ? -38.109  -48.216  0.833   1.00 28.69  ? 241  THR A OG1   1 
ATOM   1954  C CG2   . THR A 1 241 ? -37.828  -50.411  1.967   1.00 17.29  ? 241  THR A CG2   1 
ATOM   1955  N N     . LEU A 1 242 ? -37.118  -49.593  -1.747  1.00 20.28  ? 242  LEU A N     1 
ATOM   1956  C CA    . LEU A 1 242 ? -36.091  -49.933  -2.726  1.00 23.85  ? 242  LEU A CA    1 
ATOM   1957  C C     . LEU A 1 242 ? -34.793  -50.407  -2.063  1.00 25.73  ? 242  LEU A C     1 
ATOM   1958  O O     . LEU A 1 242 ? -34.140  -51.317  -2.582  1.00 25.84  ? 242  LEU A O     1 
ATOM   1959  C CB    . LEU A 1 242 ? -35.818  -48.793  -3.700  1.00 22.63  ? 242  LEU A CB    1 
ATOM   1960  C CG    . LEU A 1 242 ? -37.042  -48.312  -4.489  1.00 27.47  ? 242  LEU A CG    1 
ATOM   1961  C CD1   . LEU A 1 242 ? -36.692  -47.117  -5.361  1.00 26.33  ? 242  LEU A CD1   1 
ATOM   1962  C CD2   . LEU A 1 242 ? -37.767  -49.389  -5.272  1.00 23.70  ? 242  LEU A CD2   1 
ATOM   1963  N N     . ASN A 1 243 ? -34.414  -49.788  -0.941  1.00 22.28  ? 243  ASN A N     1 
ATOM   1964  C CA    . ASN A 1 243 ? -33.289  -50.267  -0.151  1.00 22.23  ? 243  ASN A CA    1 
ATOM   1965  C C     . ASN A 1 243 ? -33.832  -50.721  1.201   1.00 24.28  ? 243  ASN A C     1 
ATOM   1966  O O     . ASN A 1 243 ? -34.903  -51.297  1.255   1.00 24.22  ? 243  ASN A O     1 
ATOM   1967  C CB    . ASN A 1 243 ? -32.118  -49.278  -0.170  1.00 20.98  ? 243  ASN A CB    1 
ATOM   1968  C CG    . ASN A 1 243 ? -32.511  -47.898  0.328   1.00 22.81  ? 243  ASN A CG    1 
ATOM   1969  O OD1   . ASN A 1 243 ? -33.588  -47.728  0.923   1.00 21.92  ? 243  ASN A OD1   1 
ATOM   1970  N ND2   . ASN A 1 243 ? -31.652  -46.904  0.136   1.00 22.83  ? 243  ASN A ND2   1 
ATOM   1971  N N     . GLN A 1 244 ? -33.109  -50.450  2.293   1.00 26.79  ? 244  GLN A N     1 
ATOM   1972  C CA    . GLN A 1 244 ? -33.513  -50.937  3.605   1.00 23.24  ? 244  GLN A CA    1 
ATOM   1973  C C     . GLN A 1 244 ? -34.339  -49.873  4.344   1.00 22.19  ? 244  GLN A C     1 
ATOM   1974  O O     . GLN A 1 244 ? -34.892  -50.172  5.391   1.00 22.90  ? 244  GLN A O     1 
ATOM   1975  C CB    . GLN A 1 244 ? -32.262  -51.297  4.412   1.00 24.23  ? 244  GLN A CB    1 
ATOM   1976  C CG    . GLN A 1 244 ? -31.528  -52.552  3.945   1.00 24.91  ? 244  GLN A CG    1 
ATOM   1977  C CD    . GLN A 1 244 ? -32.386  -53.770  4.161   1.00 27.02  ? 244  GLN A CD    1 
ATOM   1978  O OE1   . GLN A 1 244 ? -32.743  -54.114  5.296   1.00 32.34  ? 244  GLN A OE1   1 
ATOM   1979  N NE2   . GLN A 1 244 ? -32.815  -54.379  3.071   1.00 22.32  ? 244  GLN A NE2   1 
ATOM   1980  N N     . HIS A 1 245 ? -34.428  -48.641  3.813   1.00 20.04  ? 245  HIS A N     1 
ATOM   1981  C CA    . HIS A 1 245 ? -35.018  -47.523  4.545   1.00 22.40  ? 245  HIS A CA    1 
ATOM   1982  C C     . HIS A 1 245 ? -36.218  -46.952  3.797   1.00 22.99  ? 245  HIS A C     1 
ATOM   1983  O O     . HIS A 1 245 ? -36.303  -47.106  2.589   1.00 22.91  ? 245  HIS A O     1 
ATOM   1984  C CB    . HIS A 1 245 ? -33.963  -46.456  4.844   1.00 22.05  ? 245  HIS A CB    1 
ATOM   1985  C CG    . HIS A 1 245 ? -32.869  -46.986  5.711   1.00 22.27  ? 245  HIS A CG    1 
ATOM   1986  N ND1   . HIS A 1 245 ? -31.803  -47.685  5.203   1.00 21.90  ? 245  HIS A ND1   1 
ATOM   1987  C CD2   . HIS A 1 245 ? -32.694  -46.985  7.055   1.00 22.69  ? 245  HIS A CD2   1 
ATOM   1988  C CE1   . HIS A 1 245 ? -30.996  -48.064  6.200   1.00 21.47  ? 245  HIS A CE1   1 
ATOM   1989  N NE2   . HIS A 1 245 ? -31.509  -47.640  7.325   1.00 23.02  ? 245  HIS A NE2   1 
ATOM   1990  N N     . TRP A 1 246 ? -37.134  -46.294  4.517   1.00 21.49  ? 246  TRP A N     1 
ATOM   1991  C CA    . TRP A 1 246 ? -38.312  -45.702  3.905   1.00 20.89  ? 246  TRP A CA    1 
ATOM   1992  C C     . TRP A 1 246 ? -38.051  -44.241  3.537   1.00 21.57  ? 246  TRP A C     1 
ATOM   1993  O O     . TRP A 1 246 ? -38.347  -43.840  2.417   1.00 18.47  ? 246  TRP A O     1 
ATOM   1994  C CB    . TRP A 1 246 ? -39.525  -45.857  4.835   1.00 21.53  ? 246  TRP A CB    1 
ATOM   1995  C CG    . TRP A 1 246 ? -39.838  -47.308  5.032   1.00 24.84  ? 246  TRP A CG    1 
ATOM   1996  C CD1   . TRP A 1 246 ? -39.227  -48.134  5.933   1.00 25.30  ? 246  TRP A CD1   1 
ATOM   1997  C CD2   . TRP A 1 246 ? -40.729  -48.144  4.253   1.00 26.09  ? 246  TRP A CD2   1 
ATOM   1998  N NE1   . TRP A 1 246 ? -39.689  -49.416  5.787   1.00 26.04  ? 246  TRP A NE1   1 
ATOM   1999  C CE2   . TRP A 1 246 ? -40.607  -49.462  4.768   1.00 31.10  ? 246  TRP A CE2   1 
ATOM   2000  C CE3   . TRP A 1 246 ? -41.621  -47.927  3.198   1.00 26.86  ? 246  TRP A CE3   1 
ATOM   2001  C CZ2   . TRP A 1 246 ? -41.336  -50.548  4.259   1.00 28.26  ? 246  TRP A CZ2   1 
ATOM   2002  C CZ3   . TRP A 1 246 ? -42.363  -48.990  2.711   1.00 23.49  ? 246  TRP A CZ3   1 
ATOM   2003  C CH2   . TRP A 1 246 ? -42.189  -50.286  3.205   1.00 27.59  ? 246  TRP A CH2   1 
ATOM   2004  N N     . GLY A 1 247 ? -37.540  -43.429  4.487   1.00 20.34  ? 247  GLY A N     1 
ATOM   2005  C CA    . GLY A 1 247 ? -37.018  -42.118  4.115   1.00 18.83  ? 247  GLY A CA    1 
ATOM   2006  C C     . GLY A 1 247 ? -35.679  -42.307  3.385   1.00 21.40  ? 247  GLY A C     1 
ATOM   2007  O O     . GLY A 1 247 ? -35.082  -43.377  3.449   1.00 21.83  ? 247  GLY A O     1 
ATOM   2008  N N     . ILE A 1 248 ? -35.208  -41.269  2.702   1.00 19.36  ? 248  ILE A N     1 
ATOM   2009  C CA    . ILE A 1 248 ? -33.969  -41.320  1.955   1.00 19.99  ? 248  ILE A CA    1 
ATOM   2010  C C     . ILE A 1 248 ? -32.799  -41.628  2.900   1.00 22.65  ? 248  ILE A C     1 
ATOM   2011  O O     . ILE A 1 248 ? -32.753  -41.200  4.064   1.00 21.38  ? 248  ILE A O     1 
ATOM   2012  C CB    . ILE A 1 248 ? -33.797  -39.990  1.199   1.00 21.42  ? 248  ILE A CB    1 
ATOM   2013  C CG1   . ILE A 1 248 ? -32.661  -40.034  0.210   1.00 20.53  ? 248  ILE A CG1   1 
ATOM   2014  C CG2   . ILE A 1 248 ? -33.665  -38.816  2.185   1.00 19.79  ? 248  ILE A CG2   1 
ATOM   2015  C CD1   . ILE A 1 248 ? -32.613  -38.861  -0.773  1.00 20.31  ? 248  ILE A CD1   1 
ATOM   2016  N N     . ALA A 1 249 ? -31.842  -42.400  2.379   1.00 20.38  ? 249  ALA A N     1 
ATOM   2017  C CA    . ALA A 1 249 ? -30.700  -42.858  3.152   1.00 21.97  ? 249  ALA A CA    1 
ATOM   2018  C C     . ALA A 1 249 ? -29.530  -43.011  2.176   1.00 27.57  ? 249  ALA A C     1 
ATOM   2019  O O     . ALA A 1 249 ? -29.403  -44.034  1.495   1.00 26.62  ? 249  ALA A O     1 
ATOM   2020  C CB    . ALA A 1 249 ? -31.008  -44.173  3.832   1.00 19.67  ? 249  ALA A CB    1 
ATOM   2021  N N     . ALA A 1 250 ? -28.692  -41.968  2.136   1.00 24.86  ? 250  ALA A N     1 
ATOM   2022  C CA    . ALA A 1 250 ? -27.699  -41.764  1.102   1.00 24.35  ? 250  ALA A CA    1 
ATOM   2023  C C     . ALA A 1 250 ? -26.693  -42.912  1.074   1.00 22.84  ? 250  ALA A C     1 
ATOM   2024  O O     . ALA A 1 250 ? -26.250  -43.271  -0.008  1.00 21.81  ? 250  ALA A O     1 
ATOM   2025  C CB    . ALA A 1 250 ? -26.994  -40.409  1.312   1.00 20.08  ? 250  ALA A CB    1 
ATOM   2026  N N     . ASN A 1 251 ? -26.285  -43.429  2.246   1.00 22.84  ? 251  ASN A N     1 
ATOM   2027  C CA    . ASN A 1 251 ? -25.286  -44.493  2.262   1.00 21.02  ? 251  ASN A CA    1 
ATOM   2028  C C     . ASN A 1 251 ? -25.893  -45.874  2.519   1.00 19.88  ? 251  ASN A C     1 
ATOM   2029  O O     . ASN A 1 251 ? -25.207  -46.779  3.008   1.00 16.48  ? 251  ASN A O     1 
ATOM   2030  C CB    . ASN A 1 251 ? -24.170  -44.162  3.237   1.00 21.90  ? 251  ASN A CB    1 
ATOM   2031  C CG    . ASN A 1 251 ? -23.318  -43.032  2.686   1.00 28.43  ? 251  ASN A CG    1 
ATOM   2032  O OD1   . ASN A 1 251 ? -23.007  -42.912  1.482   1.00 25.99  ? 251  ASN A OD1   1 
ATOM   2033  N ND2   . ASN A 1 251 ? -22.978  -42.139  3.587   1.00 31.00  ? 251  ASN A ND2   1 
ATOM   2034  N N     . ASP A 1 252 ? -27.178  -46.027  2.202   1.00 18.04  ? 252  ASP A N     1 
ATOM   2035  C CA    . ASP A 1 252 ? -27.764  -47.353  2.100   1.00 19.94  ? 252  ASP A CA    1 
ATOM   2036  C C     . ASP A 1 252 ? -27.644  -47.793  0.631   1.00 20.46  ? 252  ASP A C     1 
ATOM   2037  O O     . ASP A 1 252 ? -28.413  -47.306  -0.228  1.00 18.75  ? 252  ASP A O     1 
ATOM   2038  C CB    . ASP A 1 252 ? -29.201  -47.347  2.613   1.00 19.49  ? 252  ASP A CB    1 
ATOM   2039  C CG    . ASP A 1 252 ? -29.946  -48.658  2.424   1.00 22.49  ? 252  ASP A CG    1 
ATOM   2040  O OD1   . ASP A 1 252 ? -29.344  -49.598  1.826   1.00 23.14  ? 252  ASP A OD1   1 
ATOM   2041  O OD2   . ASP A 1 252 ? -31.130  -48.755  2.876   1.00 22.53  ? 252  ASP A OD2   1 
ATOM   2042  N N     . LEU A 1 253 ? -26.638  -48.661  0.351   1.00 18.20  ? 253  LEU A N     1 
ATOM   2043  C CA    . LEU A 1 253 ? -26.366  -49.120  -1.010  1.00 17.48  ? 253  LEU A CA    1 
ATOM   2044  C C     . LEU A 1 253 ? -27.100  -50.437  -1.270  1.00 17.33  ? 253  LEU A C     1 
ATOM   2045  O O     . LEU A 1 253 ? -26.982  -51.028  -2.358  1.00 15.97  ? 253  LEU A O     1 
ATOM   2046  C CB    . LEU A 1 253 ? -24.866  -49.287  -1.234  1.00 15.92  ? 253  LEU A CB    1 
ATOM   2047  C CG    . LEU A 1 253 ? -23.994  -48.126  -0.720  1.00 18.34  ? 253  LEU A CG    1 
ATOM   2048  C CD1   . LEU A 1 253 ? -22.541  -48.323  -1.134  1.00 16.99  ? 253  LEU A CD1   1 
ATOM   2049  C CD2   . LEU A 1 253 ? -24.516  -46.761  -1.211  1.00 15.39  ? 253  LEU A CD2   1 
ATOM   2050  N N     . ASN A 1 254 ? -27.799  -50.948  -0.249  1.00 14.60  ? 254  ASN A N     1 
ATOM   2051  C CA    . ASN A 1 254 ? -28.375  -52.286  -0.362  1.00 15.51  ? 254  ASN A CA    1 
ATOM   2052  C C     . ASN A 1 254 ? -29.730  -52.253  -1.089  1.00 16.53  ? 254  ASN A C     1 
ATOM   2053  O O     . ASN A 1 254 ? -30.774  -52.572  -0.505  1.00 16.66  ? 254  ASN A O     1 
ATOM   2054  C CB    . ASN A 1 254 ? -28.427  -52.899  1.032   1.00 16.00  ? 254  ASN A CB    1 
ATOM   2055  C CG    . ASN A 1 254 ? -28.840  -54.347  1.016   1.00 17.00  ? 254  ASN A CG    1 
ATOM   2056  O OD1   . ASN A 1 254 ? -28.819  -54.995  -0.033  1.00 17.73  ? 254  ASN A OD1   1 
ATOM   2057  N ND2   . ASN A 1 254 ? -29.167  -54.886  2.173   1.00 16.79  ? 254  ASN A ND2   1 
ATOM   2058  N N     . TYR A 1 255 ? -29.736  -51.839  -2.353  1.00 18.22  ? 255  TYR A N     1 
ATOM   2059  C CA    . TYR A 1 255 ? -30.952  -51.770  -3.163  1.00 18.35  ? 255  TYR A CA    1 
ATOM   2060  C C     . TYR A 1 255 ? -31.328  -53.159  -3.671  1.00 19.25  ? 255  TYR A C     1 
ATOM   2061  O O     . TYR A 1 255 ? -30.452  -53.962  -3.974  1.00 20.42  ? 255  TYR A O     1 
ATOM   2062  C CB    . TYR A 1 255 ? -30.676  -50.877  -4.368  1.00 19.14  ? 255  TYR A CB    1 
ATOM   2063  C CG    . TYR A 1 255 ? -30.864  -49.403  -4.043  1.00 21.35  ? 255  TYR A CG    1 
ATOM   2064  C CD1   . TYR A 1 255 ? -29.891  -48.693  -3.347  1.00 21.95  ? 255  TYR A CD1   1 
ATOM   2065  C CD2   . TYR A 1 255 ? -32.032  -48.728  -4.429  1.00 20.95  ? 255  TYR A CD2   1 
ATOM   2066  C CE1   . TYR A 1 255 ? -30.064  -47.348  -3.050  1.00 21.33  ? 255  TYR A CE1   1 
ATOM   2067  C CE2   . TYR A 1 255 ? -32.243  -47.403  -4.096  1.00 21.03  ? 255  TYR A CE2   1 
ATOM   2068  C CZ    . TYR A 1 255 ? -31.236  -46.717  -3.433  1.00 22.56  ? 255  TYR A CZ    1 
ATOM   2069  O OH    . TYR A 1 255 ? -31.407  -45.415  -3.118  1.00 25.27  ? 255  TYR A OH    1 
ATOM   2070  N N     . LYS A 1 256 ? -32.633  -53.447  -3.735  1.00 19.36  ? 256  LYS A N     1 
ATOM   2071  C CA    . LYS A 1 256 ? -33.142  -54.657  -4.351  1.00 19.86  ? 256  LYS A CA    1 
ATOM   2072  C C     . LYS A 1 256 ? -33.019  -54.517  -5.863  1.00 23.33  ? 256  LYS A C     1 
ATOM   2073  O O     . LYS A 1 256 ? -32.930  -53.400  -6.371  1.00 21.02  ? 256  LYS A O     1 
ATOM   2074  C CB    . LYS A 1 256 ? -34.610  -54.777  -3.970  1.00 24.23  ? 256  LYS A CB    1 
ATOM   2075  C CG    . LYS A 1 256 ? -34.827  -54.916  -2.457  1.00 27.77  ? 256  LYS A CG    1 
ATOM   2076  C CD    . LYS A 1 256 ? -36.312  -54.838  -2.100  1.00 24.73  ? 256  LYS A CD    1 
ATOM   2077  C CE    . LYS A 1 256 ? -36.496  -54.815  -0.587  1.00 26.51  ? 256  LYS A CE    1 
ATOM   2078  N NZ    . LYS A 1 256 ? -35.741  -53.709  0.040   1.00 26.32  ? 256  LYS A NZ    1 
ATOM   2079  N N     . SER A 1 257 ? -32.992  -55.643  -6.594  1.00 21.33  ? 257  SER A N     1 
ATOM   2080  C CA    . SER A 1 257 ? -32.934  -55.528  -8.040  1.00 21.37  ? 257  SER A CA    1 
ATOM   2081  C C     . SER A 1 257 ? -34.283  -55.040  -8.582  1.00 21.40  ? 257  SER A C     1 
ATOM   2082  O O     . SER A 1 257 ? -35.339  -55.360  -8.021  1.00 21.30  ? 257  SER A O     1 
ATOM   2083  C CB    . SER A 1 257 ? -32.564  -56.850  -8.667  1.00 19.31  ? 257  SER A CB    1 
ATOM   2084  O OG    . SER A 1 257 ? -33.640  -57.741  -8.510  1.00 21.68  ? 257  SER A OG    1 
ATOM   2085  N N     . PRO A 1 258 ? -34.277  -54.299  -9.708  1.00 17.87  ? 258  PRO A N     1 
ATOM   2086  C CA    . PRO A 1 258 ? -35.512  -54.046  -10.449 1.00 18.30  ? 258  PRO A CA    1 
ATOM   2087  C C     . PRO A 1 258 ? -36.315  -55.325  -10.720 1.00 20.14  ? 258  PRO A C     1 
ATOM   2088  O O     . PRO A 1 258 ? -37.550  -55.313  -10.650 1.00 20.34  ? 258  PRO A O     1 
ATOM   2089  C CB    . PRO A 1 258 ? -35.044  -53.265  -11.685 1.00 16.42  ? 258  PRO A CB    1 
ATOM   2090  C CG    . PRO A 1 258 ? -33.755  -52.578  -11.154 1.00 16.15  ? 258  PRO A CG    1 
ATOM   2091  C CD    . PRO A 1 258 ? -33.098  -53.631  -10.277 1.00 15.70  ? 258  PRO A CD    1 
ATOM   2092  N N     . ALA A 1 259 ? -35.618  -56.448  -10.944 1.00 18.71  ? 259  ALA A N     1 
ATOM   2093  C CA    . ALA A 1 259 ? -36.309  -57.708  -11.216 1.00 22.38  ? 259  ALA A CA    1 
ATOM   2094  C C     . ALA A 1 259 ? -37.141  -58.140  -10.003 1.00 24.58  ? 259  ALA A C     1 
ATOM   2095  O O     . ALA A 1 259 ? -38.295  -58.563  -10.150 1.00 25.32  ? 259  ALA A O     1 
ATOM   2096  C CB    . ALA A 1 259 ? -35.328  -58.814  -11.619 1.00 19.66  ? 259  ALA A CB    1 
ATOM   2097  N N     . GLU A 1 260 ? -36.544  -58.023  -8.808  1.00 23.80  ? 260  GLU A N     1 
ATOM   2098  C CA    . GLU A 1 260 ? -37.244  -58.403  -7.592  1.00 24.25  ? 260  GLU A CA    1 
ATOM   2099  C C     . GLU A 1 260 ? -38.463  -57.492  -7.402  1.00 22.12  ? 260  GLU A C     1 
ATOM   2100  O O     . GLU A 1 260 ? -39.525  -57.935  -6.972  1.00 22.31  ? 260  GLU A O     1 
ATOM   2101  C CB    . GLU A 1 260 ? -36.292  -58.410  -6.396  1.00 23.43  ? 260  GLU A CB    1 
ATOM   2102  C CG    . GLU A 1 260 ? -37.045  -58.670  -5.091  1.00 31.31  ? 260  GLU A CG    1 
ATOM   2103  C CD    . GLU A 1 260 ? -36.257  -58.711  -3.781  1.00 35.36  ? 260  GLU A CD    1 
ATOM   2104  O OE1   . GLU A 1 260 ? -35.021  -58.647  -3.829  1.00 37.36  ? 260  GLU A OE1   1 
ATOM   2105  O OE2   . GLU A 1 260 ? -36.844  -58.771  -2.696  1.00 41.87  ? 260  GLU A OE2   1 
ATOM   2106  N N     . MET A 1 261 ? -38.311  -56.214  -7.737  1.00 18.34  ? 261  MET A N     1 
ATOM   2107  C CA    . MET A 1 261 ? -39.416  -55.276  -7.632  1.00 19.00  ? 261  MET A CA    1 
ATOM   2108  C C     . MET A 1 261 ? -40.575  -55.726  -8.541  1.00 21.31  ? 261  MET A C     1 
ATOM   2109  O O     . MET A 1 261 ? -41.719  -55.812  -8.092  1.00 22.31  ? 261  MET A O     1 
ATOM   2110  C CB    . MET A 1 261 ? -38.940  -53.855  -7.971  1.00 19.97  ? 261  MET A CB    1 
ATOM   2111  C CG    . MET A 1 261 ? -40.065  -52.844  -8.101  1.00 23.16  ? 261  MET A CG    1 
ATOM   2112  S SD    . MET A 1 261 ? -39.516  -51.257  -8.763  1.00 27.31  ? 261  MET A SD    1 
ATOM   2113  C CE    . MET A 1 261 ? -38.854  -51.693  -10.392 1.00 26.13  ? 261  MET A CE    1 
ATOM   2114  N N     . ILE A 1 262 ? -40.280  -56.071  -9.809  1.00 20.11  ? 262  ILE A N     1 
ATOM   2115  C CA    . ILE A 1 262 ? -41.317  -56.531  -10.707 1.00 19.52  ? 262  ILE A CA    1 
ATOM   2116  C C     . ILE A 1 262 ? -41.958  -57.825  -10.177 1.00 19.53  ? 262  ILE A C     1 
ATOM   2117  O O     . ILE A 1 262 ? -43.177  -57.932  -10.171 1.00 15.46  ? 262  ILE A O     1 
ATOM   2118  C CB    . ILE A 1 262 ? -40.790  -56.665  -12.139 1.00 19.92  ? 262  ILE A CB    1 
ATOM   2119  C CG1   . ILE A 1 262 ? -40.556  -55.272  -12.710 1.00 18.39  ? 262  ILE A CG1   1 
ATOM   2120  C CG2   . ILE A 1 262 ? -41.745  -57.507  -13.021 1.00 19.58  ? 262  ILE A CG2   1 
ATOM   2121  C CD1   . ILE A 1 262 ? -39.632  -55.261  -13.917 1.00 18.11  ? 262  ILE A CD1   1 
ATOM   2122  N N     . GLU A 1 263 ? -41.145  -58.785  -9.712  1.00 18.06  ? 263  GLU A N     1 
ATOM   2123  C CA    . GLU A 1 263 ? -41.693  -60.013  -9.167  1.00 20.97  ? 263  GLU A CA    1 
ATOM   2124  C C     . GLU A 1 263 ? -42.603  -59.744  -7.957  1.00 22.21  ? 263  GLU A C     1 
ATOM   2125  O O     . GLU A 1 263 ? -43.579  -60.460  -7.752  1.00 24.00  ? 263  GLU A O     1 
ATOM   2126  C CB    . GLU A 1 263 ? -40.607  -61.026  -8.794  1.00 22.34  ? 263  GLU A CB    1 
ATOM   2127  C CG    . GLU A 1 263 ? -39.855  -61.581  -10.004 1.00 26.11  ? 263  GLU A CG    1 
ATOM   2128  C CD    . GLU A 1 263 ? -38.940  -62.778  -9.753  1.00 32.61  ? 263  GLU A CD    1 
ATOM   2129  O OE1   . GLU A 1 263 ? -38.916  -63.220  -8.578  1.00 40.43  ? 263  GLU A OE1   1 
ATOM   2130  O OE2   . GLU A 1 263 ? -38.285  -63.301  -10.701 1.00 31.01  ? 263  GLU A OE2   1 
ATOM   2131  N N     . THR A 1 264 ? -42.263  -58.785  -7.135  1.00 20.67  ? 264  THR A N     1 
ATOM   2132  C CA    . THR A 1 264 ? -43.041  -58.443  -5.981  1.00 21.99  ? 264  THR A CA    1 
ATOM   2133  C C     . THR A 1 264 ? -44.408  -57.889  -6.304  1.00 21.35  ? 264  THR A C     1 
ATOM   2134  O O     . THR A 1 264 ? -45.355  -58.175  -5.656  1.00 18.81  ? 264  THR A O     1 
ATOM   2135  C CB    . THR A 1 264 ? -42.249  -57.541  -5.028  1.00 22.20  ? 264  THR A CB    1 
ATOM   2136  O OG1   . THR A 1 264 ? -41.021  -58.166  -4.755  1.00 23.90  ? 264  THR A OG1   1 
ATOM   2137  C CG2   . THR A 1 264 ? -42.945  -57.353  -3.779  1.00 17.11  ? 264  THR A CG2   1 
ATOM   2138  N N     . VAL A 1 265 ? -44.455  -57.051  -7.307  1.00 19.61  ? 265  VAL A N     1 
ATOM   2139  C CA    . VAL A 1 265 ? -45.666  -56.449  -7.772  1.00 18.92  ? 265  VAL A CA    1 
ATOM   2140  C C     . VAL A 1 265 ? -46.591  -57.522  -8.314  1.00 23.34  ? 265  VAL A C     1 
ATOM   2141  O O     . VAL A 1 265 ? -47.758  -57.547  -8.012  1.00 26.10  ? 265  VAL A O     1 
ATOM   2142  C CB    . VAL A 1 265 ? -45.375  -55.403  -8.852  1.00 18.05  ? 265  VAL A CB    1 
ATOM   2143  C CG1   . VAL A 1 265 ? -46.604  -55.059  -9.649  1.00 19.14  ? 265  VAL A CG1   1 
ATOM   2144  C CG2   . VAL A 1 265 ? -44.741  -54.183  -8.281  1.00 16.35  ? 265  VAL A CG2   1 
ATOM   2145  N N     . ALA A 1 266 ? -46.033  -58.435  -9.075  1.00 20.66  ? 266  ALA A N     1 
ATOM   2146  C CA    . ALA A 1 266 ? -46.781  -59.528  -9.629  1.00 21.21  ? 266  ALA A CA    1 
ATOM   2147  C C     . ALA A 1 266 ? -47.337  -60.436  -8.553  1.00 21.14  ? 266  ALA A C     1 
ATOM   2148  O O     . ALA A 1 266 ? -48.434  -60.882  -8.621  1.00 19.94  ? 266  ALA A O     1 
ATOM   2149  C CB    . ALA A 1 266 ? -45.939  -60.312  -10.617 1.00 19.44  ? 266  ALA A CB    1 
ATOM   2150  N N     . HIS A 1 267 ? -46.529  -60.664  -7.548  1.00 21.55  ? 267  HIS A N     1 
ATOM   2151  C CA    . HIS A 1 267 ? -46.840  -61.495  -6.427  1.00 22.72  ? 267  HIS A CA    1 
ATOM   2152  C C     . HIS A 1 267 ? -48.000  -61.006  -5.591  1.00 21.04  ? 267  HIS A C     1 
ATOM   2153  O O     . HIS A 1 267 ? -48.795  -61.776  -5.158  1.00 22.92  ? 267  HIS A O     1 
ATOM   2154  C CB    . HIS A 1 267 ? -45.580  -61.739  -5.616  1.00 22.34  ? 267  HIS A CB    1 
ATOM   2155  C CG    . HIS A 1 267 ? -45.814  -62.417  -4.322  1.00 22.26  ? 267  HIS A CG    1 
ATOM   2156  N ND1   . HIS A 1 267 ? -46.020  -63.761  -4.220  1.00 24.24  ? 267  HIS A ND1   1 
ATOM   2157  C CD2   . HIS A 1 267 ? -45.855  -61.934  -3.071  1.00 20.70  ? 267  HIS A CD2   1 
ATOM   2158  C CE1   . HIS A 1 267 ? -46.207  -64.076  -2.963  1.00 25.40  ? 267  HIS A CE1   1 
ATOM   2159  N NE2   . HIS A 1 267 ? -46.099  -62.985  -2.244  1.00 23.03  ? 267  HIS A NE2   1 
ATOM   2160  N N     . ALA A 1 268 ? -48.089  -59.699  -5.429  1.00 20.16  ? 268  ALA A N     1 
ATOM   2161  C CA    . ALA A 1 268 ? -49.145  -59.062  -4.697  1.00 19.18  ? 268  ALA A CA    1 
ATOM   2162  C C     . ALA A 1 268 ? -50.448  -59.356  -5.364  1.00 19.97  ? 268  ALA A C     1 
ATOM   2163  O O     . ALA A 1 268 ? -51.366  -59.716  -4.729  1.00 22.34  ? 268  ALA A O     1 
ATOM   2164  C CB    . ALA A 1 268 ? -48.927  -57.574  -4.646  1.00 19.17  ? 268  ALA A CB    1 
ATOM   2165  N N     . ARG A 1 269 ? -50.491  -59.242  -6.666  1.00 19.22  ? 269  ARG A N     1 
ATOM   2166  C CA    . ARG A 1 269 ? -51.675  -59.531  -7.423  1.00 19.03  ? 269  ARG A CA    1 
ATOM   2167  C C     . ARG A 1 269 ? -52.097  -60.986  -7.309  1.00 21.49  ? 269  ARG A C     1 
ATOM   2168  O O     . ARG A 1 269 ? -53.242  -61.289  -7.168  1.00 25.00  ? 269  ARG A O     1 
ATOM   2169  C CB    . ARG A 1 269 ? -51.505  -59.088  -8.861  1.00 15.63  ? 269  ARG A CB    1 
ATOM   2170  C CG    . ARG A 1 269 ? -51.181  -57.630  -9.009  1.00 15.36  ? 269  ARG A CG    1 
ATOM   2171  C CD    . ARG A 1 269 ? -51.971  -56.717  -8.127  1.00 16.08  ? 269  ARG A CD    1 
ATOM   2172  N NE    . ARG A 1 269 ? -53.258  -56.419  -8.672  1.00 18.48  ? 269  ARG A NE    1 
ATOM   2173  C CZ    . ARG A 1 269 ? -54.278  -55.933  -8.006  1.00 19.53  ? 269  ARG A CZ    1 
ATOM   2174  N NH1   . ARG A 1 269 ? -54.216  -55.726  -6.741  1.00 18.89  ? 269  ARG A NH1   1 
ATOM   2175  N NH2   . ARG A 1 269 ? -55.368  -55.694  -8.625  1.00 17.57  ? 269  ARG A NH2   1 
ATOM   2176  N N     . HIS A 1 270 ? -51.127  -61.862  -7.323  1.00 21.18  ? 270  HIS A N     1 
ATOM   2177  C CA    . HIS A 1 270 ? -51.318  -63.269  -7.180  1.00 21.37  ? 270  HIS A CA    1 
ATOM   2178  C C     . HIS A 1 270 ? -51.933  -63.626  -5.834  1.00 21.84  ? 270  HIS A C     1 
ATOM   2179  O O     . HIS A 1 270 ? -52.751  -64.470  -5.780  1.00 19.83  ? 270  HIS A O     1 
ATOM   2180  C CB    . HIS A 1 270 ? -50.004  -64.008  -7.412  1.00 23.66  ? 270  HIS A CB    1 
ATOM   2181  C CG    . HIS A 1 270 ? -50.083  -65.483  -7.182  1.00 30.79  ? 270  HIS A CG    1 
ATOM   2182  N ND1   . HIS A 1 270 ? -49.127  -66.179  -6.501  1.00 31.77  ? 270  HIS A ND1   1 
ATOM   2183  C CD2   . HIS A 1 270 ? -51.003  -66.390  -7.555  1.00 26.69  ? 270  HIS A CD2   1 
ATOM   2184  C CE1   . HIS A 1 270 ? -49.460  -67.446  -6.455  1.00 28.27  ? 270  HIS A CE1   1 
ATOM   2185  N NE2   . HIS A 1 270 ? -50.595  -67.596  -7.084  1.00 27.47  ? 270  HIS A NE2   1 
ATOM   2186  N N     . ILE A 1 271 ? -51.561  -62.957  -4.763  1.00 21.41  ? 271  ILE A N     1 
ATOM   2187  C CA    . ILE A 1 271 ? -52.133  -63.328  -3.467  1.00 22.12  ? 271  ILE A CA    1 
ATOM   2188  C C     . ILE A 1 271 ? -53.360  -62.461  -3.149  1.00 24.09  ? 271  ILE A C     1 
ATOM   2189  O O     . ILE A 1 271 ? -53.897  -62.544  -2.036  1.00 26.64  ? 271  ILE A O     1 
ATOM   2190  C CB    . ILE A 1 271 ? -51.089  -63.225  -2.329  1.00 20.02  ? 271  ILE A CB    1 
ATOM   2191  C CG1   . ILE A 1 271 ? -50.604  -61.767  -2.123  1.00 18.45  ? 271  ILE A CG1   1 
ATOM   2192  C CG2   . ILE A 1 271 ? -49.924  -64.192  -2.523  1.00 16.06  ? 271  ILE A CG2   1 
ATOM   2193  C CD1   . ILE A 1 271 ? -49.738  -61.575  -0.906  1.00 18.14  ? 271  ILE A CD1   1 
ATOM   2194  N N     . GLY A 1 272 ? -53.777  -61.593  -4.083  1.00 25.35  ? 272  GLY A N     1 
ATOM   2195  C CA    . GLY A 1 272 ? -55.005  -60.834  -3.885  1.00 21.73  ? 272  GLY A CA    1 
ATOM   2196  C C     . GLY A 1 272 ? -54.803  -59.557  -3.051  1.00 23.39  ? 272  GLY A C     1 
ATOM   2197  O O     . GLY A 1 272 ? -55.675  -59.214  -2.246  1.00 28.67  ? 272  GLY A O     1 
ATOM   2198  N N     . ALA A 1 273 ? -53.688  -58.831  -3.271  1.00 17.93  ? 273  ALA A N     1 
ATOM   2199  C CA    . ALA A 1 273 ? -53.375  -57.640  -2.496  1.00 18.71  ? 273  ALA A CA    1 
ATOM   2200  C C     . ALA A 1 273 ? -52.994  -56.515  -3.465  1.00 21.22  ? 273  ALA A C     1 
ATOM   2201  O O     . ALA A 1 273 ? -52.631  -56.782  -4.612  1.00 20.49  ? 273  ALA A O     1 
ATOM   2202  C CB    . ALA A 1 273 ? -52.237  -57.908  -1.516  1.00 16.08  ? 273  ALA A CB    1 
ATOM   2203  N N     . ASN A 1 274 ? -53.093  -55.265  -2.993  1.00 18.10  ? 274  ASN A N     1 
ATOM   2204  C CA    . ASN A 1 274 ? -52.436  -54.174  -3.680  1.00 18.33  ? 274  ASN A CA    1 
ATOM   2205  C C     . ASN A 1 274 ? -50.958  -54.163  -3.269  1.00 20.37  ? 274  ASN A C     1 
ATOM   2206  O O     . ASN A 1 274 ? -50.567  -54.813  -2.295  1.00 18.21  ? 274  ASN A O     1 
ATOM   2207  C CB    . ASN A 1 274 ? -53.086  -52.842  -3.309  1.00 19.16  ? 274  ASN A CB    1 
ATOM   2208  C CG    . ASN A 1 274 ? -54.386  -52.592  -4.052  1.00 21.66  ? 274  ASN A CG    1 
ATOM   2209  O OD1   . ASN A 1 274 ? -54.999  -53.522  -4.609  1.00 20.51  ? 274  ASN A OD1   1 
ATOM   2210  N ND2   . ASN A 1 274 ? -54.833  -51.341  -4.051  1.00 19.79  ? 274  ASN A ND2   1 
ATOM   2211  N N     . ILE A 1 275 ? -50.162  -53.406  -3.982  1.00 17.81  ? 275  ILE A N     1 
ATOM   2212  C CA    . ILE A 1 275 ? -48.783  -53.216  -3.688  1.00 19.33  ? 275  ILE A CA    1 
ATOM   2213  C C     . ILE A 1 275 ? -48.410  -51.713  -3.675  1.00 20.39  ? 275  ILE A C     1 
ATOM   2214  O O     . ILE A 1 275 ? -48.830  -51.013  -4.533  1.00 20.62  ? 275  ILE A O     1 
ATOM   2215  C CB    . ILE A 1 275 ? -47.898  -53.990  -4.688  1.00 21.06  ? 275  ILE A CB    1 
ATOM   2216  C CG1   . ILE A 1 275 ? -46.436  -53.653  -4.512  1.00 21.29  ? 275  ILE A CG1   1 
ATOM   2217  C CG2   . ILE A 1 275 ? -48.233  -53.638  -6.108  1.00 19.23  ? 275  ILE A CG2   1 
ATOM   2218  C CD1   . ILE A 1 275 ? -45.784  -54.307  -3.360  1.00 24.41  ? 275  ILE A CD1   1 
ATOM   2219  N N     . LEU A 1 276 ? -47.729  -51.239  -2.639  1.00 18.48  ? 276  LEU A N     1 
ATOM   2220  C CA    . LEU A 1 276 ? -47.137  -49.908  -2.621  1.00 21.99  ? 276  LEU A CA    1 
ATOM   2221  C C     . LEU A 1 276 ? -45.637  -50.029  -2.878  1.00 21.52  ? 276  LEU A C     1 
ATOM   2222  O O     . LEU A 1 276 ? -44.969  -50.820  -2.206  1.00 22.59  ? 276  LEU A O     1 
ATOM   2223  C CB    . LEU A 1 276 ? -47.343  -49.264  -1.240  1.00 22.77  ? 276  LEU A CB    1 
ATOM   2224  C CG    . LEU A 1 276 ? -48.757  -48.863  -0.849  1.00 21.54  ? 276  LEU A CG    1 
ATOM   2225  C CD1   . LEU A 1 276 ? -48.724  -48.176  0.511   1.00 20.13  ? 276  LEU A CD1   1 
ATOM   2226  C CD2   . LEU A 1 276 ? -49.320  -47.939  -1.938  1.00 23.85  ? 276  LEU A CD2   1 
ATOM   2227  N N     . VAL A 1 277 ? -45.120  -49.221  -3.809  1.00 19.51  ? 277  VAL A N     1 
ATOM   2228  C CA    . VAL A 1 277 ? -43.686  -49.106  -4.006  1.00 21.19  ? 277  VAL A CA    1 
ATOM   2229  C C     . VAL A 1 277 ? -43.268  -47.758  -3.425  1.00 20.29  ? 277  VAL A C     1 
ATOM   2230  O O     . VAL A 1 277 ? -43.797  -46.728  -3.819  1.00 16.95  ? 277  VAL A O     1 
ATOM   2231  C CB    . VAL A 1 277 ? -43.314  -49.219  -5.499  1.00 22.64  ? 277  VAL A CB    1 
ATOM   2232  C CG1   . VAL A 1 277 ? -41.819  -49.052  -5.724  1.00 21.38  ? 277  VAL A CG1   1 
ATOM   2233  C CG2   . VAL A 1 277 ? -43.748  -50.549  -6.074  1.00 20.82  ? 277  VAL A CG2   1 
ATOM   2234  N N     . ASN A 1 278 ? -42.302  -47.786  -2.502  1.00 21.26  ? 278  ASN A N     1 
ATOM   2235  C CA    . ASN A 1 278 ? -41.957  -46.628  -1.715  1.00 19.72  ? 278  ASN A CA    1 
ATOM   2236  C C     . ASN A 1 278 ? -40.776  -45.876  -2.313  1.00 22.38  ? 278  ASN A C     1 
ATOM   2237  O O     . ASN A 1 278 ? -39.790  -46.487  -2.719  1.00 24.09  ? 278  ASN A O     1 
ATOM   2238  C CB    . ASN A 1 278 ? -41.541  -47.025  -0.307  1.00 20.14  ? 278  ASN A CB    1 
ATOM   2239  C CG    . ASN A 1 278 ? -41.159  -45.779  0.464   1.00 22.86  ? 278  ASN A CG    1 
ATOM   2240  O OD1   . ASN A 1 278 ? -42.029  -44.918  0.702   1.00 22.56  ? 278  ASN A OD1   1 
ATOM   2241  N ND2   . ASN A 1 278 ? -39.877  -45.631  0.791   1.00 19.74  ? 278  ASN A ND2   1 
ATOM   2242  N N     . ILE A 1 279 ? -40.861  -44.538  -2.312  1.00 21.98  ? 279  ILE A N     1 
ATOM   2243  C CA    . ILE A 1 279 ? -39.696  -43.702  -2.569  1.00 22.58  ? 279  ILE A CA    1 
ATOM   2244  C C     . ILE A 1 279 ? -39.570  -42.675  -1.428  1.00 24.09  ? 279  ILE A C     1 
ATOM   2245  O O     . ILE A 1 279 ? -40.566  -42.179  -0.882  1.00 23.46  ? 279  ILE A O     1 
ATOM   2246  C CB    . ILE A 1 279 ? -39.818  -43.012  -3.943  1.00 21.74  ? 279  ILE A CB    1 
ATOM   2247  C CG1   . ILE A 1 279 ? -40.899  -41.995  -3.939  1.00 21.50  ? 279  ILE A CG1   1 
ATOM   2248  C CG2   . ILE A 1 279 ? -40.024  -44.006  -5.099  1.00 20.32  ? 279  ILE A CG2   1 
ATOM   2249  C CD1   . ILE A 1 279 ? -40.966  -41.204  -5.233  1.00 27.48  ? 279  ILE A CD1   1 
ATOM   2250  N N     . GLY A 1 280 ? -38.338  -42.318  -1.066  1.00 22.94  ? 280  GLY A N     1 
ATOM   2251  C CA    . GLY A 1 280 ? -38.081  -41.254  -0.094  1.00 21.08  ? 280  GLY A CA    1 
ATOM   2252  C C     . GLY A 1 280 ? -37.604  -39.993  -0.810  1.00 22.43  ? 280  GLY A C     1 
ATOM   2253  O O     . GLY A 1 280 ? -36.637  -40.065  -1.554  1.00 25.16  ? 280  GLY A O     1 
ATOM   2254  N N     . LEU A 1 281 ? -38.273  -38.845  -0.624  1.00 20.94  ? 281  LEU A N     1 
ATOM   2255  C CA    . LEU A 1 281 ? -37.825  -37.613  -1.287  1.00 20.39  ? 281  LEU A CA    1 
ATOM   2256  C C     . LEU A 1 281 ? -36.562  -37.057  -0.611  1.00 19.81  ? 281  LEU A C     1 
ATOM   2257  O O     . LEU A 1 281 ? -36.257  -37.390  0.542   1.00 16.88  ? 281  LEU A O     1 
ATOM   2258  C CB    . LEU A 1 281 ? -38.950  -36.571  -1.290  1.00 21.80  ? 281  LEU A CB    1 
ATOM   2259  C CG    . LEU A 1 281 ? -40.294  -37.010  -1.877  1.00 20.96  ? 281  LEU A CG    1 
ATOM   2260  C CD1   . LEU A 1 281 ? -41.307  -35.892  -1.941  1.00 19.44  ? 281  LEU A CD1   1 
ATOM   2261  C CD2   . LEU A 1 281 ? -40.140  -37.677  -3.267  1.00 18.25  ? 281  LEU A CD2   1 
ATOM   2262  N N     . THR A 1 282 ? -35.820  -36.213  -1.340  1.00 18.68  ? 282  THR A N     1 
ATOM   2263  C CA    . THR A 1 282 ? -34.718  -35.436  -0.766  1.00 20.05  ? 282  THR A CA    1 
ATOM   2264  C C     . THR A 1 282 ? -35.264  -34.427  0.248   1.00 21.82  ? 282  THR A C     1 
ATOM   2265  O O     . THR A 1 282 ? -36.478  -34.161  0.298   1.00 20.32  ? 282  THR A O     1 
ATOM   2266  C CB    . THR A 1 282 ? -33.919  -34.706  -1.857  1.00 20.07  ? 282  THR A CB    1 
ATOM   2267  O OG1   . THR A 1 282 ? -34.773  -33.661  -2.349  1.00 19.66  ? 282  THR A OG1   1 
ATOM   2268  C CG2   . THR A 1 282 ? -33.461  -35.630  -2.986  1.00 16.75  ? 282  THR A CG2   1 
ATOM   2269  N N     . GLY A 1 283 ? -34.347  -33.822  1.022   1.00 21.75  ? 283  GLY A N     1 
ATOM   2270  C CA    . GLY A 1 283 ? -34.742  -32.826  2.015   1.00 20.20  ? 283  GLY A CA    1 
ATOM   2271  C C     . GLY A 1 283 ? -35.681  -31.775  1.407   1.00 20.79  ? 283  GLY A C     1 
ATOM   2272  O O     . GLY A 1 283 ? -36.687  -31.442  2.027   1.00 23.73  ? 283  GLY A O     1 
ATOM   2273  N N     . THR A 1 284 ? -35.392  -31.304  0.186   1.00 19.41  ? 284  THR A N     1 
ATOM   2274  C CA    . THR A 1 284 ? -36.155  -30.221  -0.415  1.00 22.94  ? 284  THR A CA    1 
ATOM   2275  C C     . THR A 1 284 ? -37.334  -30.762  -1.241  1.00 26.69  ? 284  THR A C     1 
ATOM   2276  O O     . THR A 1 284 ? -38.038  -29.970  -1.877  1.00 23.75  ? 284  THR A O     1 
ATOM   2277  C CB    . THR A 1 284 ? -35.249  -29.337  -1.285  1.00 26.31  ? 284  THR A CB    1 
ATOM   2278  O OG1   . THR A 1 284 ? -34.690  -30.250  -2.229  1.00 28.63  ? 284  THR A OG1   1 
ATOM   2279  C CG2   . THR A 1 284 ? -34.172  -28.615  -0.495  1.00 19.90  ? 284  THR A CG2   1 
ATOM   2280  N N     . GLY A 1 285 ? -37.577  -32.088  -1.230  1.00 23.26  ? 285  GLY A N     1 
ATOM   2281  C CA    . GLY A 1 285 ? -38.794  -32.597  -1.843  1.00 23.68  ? 285  GLY A CA    1 
ATOM   2282  C C     . GLY A 1 285 ? -38.647  -33.104  -3.290  1.00 24.90  ? 285  GLY A C     1 
ATOM   2283  O O     . GLY A 1 285 ? -39.668  -33.322  -3.947  1.00 25.25  ? 285  GLY A O     1 
ATOM   2284  N N     . ALA A 1 286 ? -37.417  -33.334  -3.786  1.00 21.65  ? 286  ALA A N     1 
ATOM   2285  C CA    . ALA A 1 286 ? -37.252  -33.917  -5.118  1.00 21.88  ? 286  ALA A CA    1 
ATOM   2286  C C     . ALA A 1 286 ? -37.314  -35.452  -5.053  1.00 22.29  ? 286  ALA A C     1 
ATOM   2287  O O     . ALA A 1 286 ? -36.961  -36.059  -4.034  1.00 22.52  ? 286  ALA A O     1 
ATOM   2288  C CB    . ALA A 1 286 ? -35.921  -33.487  -5.728  1.00 19.98  ? 286  ALA A CB    1 
ATOM   2289  N N     . ILE A 1 287 ? -37.748  -36.072  -6.160  1.00 21.77  ? 287  ILE A N     1 
ATOM   2290  C CA    . ILE A 1 287 ? -37.576  -37.504  -6.342  1.00 22.56  ? 287  ILE A CA    1 
ATOM   2291  C C     . ILE A 1 287 ? -36.113  -37.772  -6.635  1.00 20.04  ? 287  ILE A C     1 
ATOM   2292  O O     . ILE A 1 287 ? -35.570  -37.253  -7.598  1.00 21.23  ? 287  ILE A O     1 
ATOM   2293  C CB    . ILE A 1 287 ? -38.461  -38.022  -7.491  1.00 24.65  ? 287  ILE A CB    1 
ATOM   2294  C CG1   . ILE A 1 287 ? -39.914  -37.701  -7.242  1.00 27.59  ? 287  ILE A CG1   1 
ATOM   2295  C CG2   . ILE A 1 287 ? -38.263  -39.524  -7.673  1.00 23.72  ? 287  ILE A CG2   1 
ATOM   2296  C CD1   . ILE A 1 287 ? -40.817  -38.179  -8.361  1.00 32.51  ? 287  ILE A CD1   1 
ATOM   2297  N N     . PRO A 1 288 ? -35.397  -38.561  -5.828  1.00 18.97  ? 288  PRO A N     1 
ATOM   2298  C CA    . PRO A 1 288 ? -33.975  -38.798  -6.102  1.00 19.18  ? 288  PRO A CA    1 
ATOM   2299  C C     . PRO A 1 288 ? -33.763  -39.625  -7.373  1.00 20.96  ? 288  PRO A C     1 
ATOM   2300  O O     . PRO A 1 288 ? -34.643  -40.397  -7.761  1.00 19.80  ? 288  PRO A O     1 
ATOM   2301  C CB    . PRO A 1 288 ? -33.458  -39.525  -4.879  1.00 17.64  ? 288  PRO A CB    1 
ATOM   2302  C CG    . PRO A 1 288 ? -34.680  -39.923  -4.081  1.00 16.55  ? 288  PRO A CG    1 
ATOM   2303  C CD    . PRO A 1 288 ? -35.916  -39.261  -4.651  1.00 20.02  ? 288  PRO A CD    1 
ATOM   2304  N N     . ALA A 1 289 ? -32.601  -39.458  -8.012  1.00 22.52  ? 289  ALA A N     1 
ATOM   2305  C CA    . ALA A 1 289 ? -32.315  -40.088  -9.299  1.00 22.39  ? 289  ALA A CA    1 
ATOM   2306  C C     . ALA A 1 289 ? -32.456  -41.616  -9.215  1.00 20.72  ? 289  ALA A C     1 
ATOM   2307  O O     . ALA A 1 289 ? -33.041  -42.215  -10.117 1.00 22.42  ? 289  ALA A O     1 
ATOM   2308  C CB    . ALA A 1 289 ? -30.974  -39.619  -9.875  1.00 17.88  ? 289  ALA A CB    1 
ATOM   2309  N N     . ALA A 1 290 ? -31.994  -42.236  -8.126  1.00 22.41  ? 290  ALA A N     1 
ATOM   2310  C CA    . ALA A 1 290 ? -32.133  -43.697  -8.006  1.00 23.77  ? 290  ALA A CA    1 
ATOM   2311  C C     . ALA A 1 290 ? -33.596  -44.136  -8.085  1.00 23.79  ? 290  ALA A C     1 
ATOM   2312  O O     . ALA A 1 290 ? -33.926  -45.103  -8.771  1.00 24.60  ? 290  ALA A O     1 
ATOM   2313  C CB    . ALA A 1 290 ? -31.456  -44.261  -6.755  1.00 21.37  ? 290  ALA A CB    1 
ATOM   2314  N N     . ALA A 1 291 ? -34.483  -43.402  -7.397  1.00 21.61  ? 291  ALA A N     1 
ATOM   2315  C CA    . ALA A 1 291 ? -35.885  -43.775  -7.392  1.00 21.59  ? 291  ALA A CA    1 
ATOM   2316  C C     . ALA A 1 291 ? -36.479  -43.634  -8.797  1.00 24.78  ? 291  ALA A C     1 
ATOM   2317  O O     . ALA A 1 291 ? -37.304  -44.469  -9.203  1.00 24.64  ? 291  ALA A O     1 
ATOM   2318  C CB    . ALA A 1 291 ? -36.642  -42.939  -6.397  1.00 22.03  ? 291  ALA A CB    1 
ATOM   2319  N N     . GLN A 1 292 ? -36.064  -42.581  -9.530  1.00 20.36  ? 292  GLN A N     1 
ATOM   2320  C CA    . GLN A 1 292 ? -36.532  -42.378  -10.884 1.00 24.28  ? 292  GLN A CA    1 
ATOM   2321  C C     . GLN A 1 292 ? -36.167  -43.586  -11.762 1.00 24.13  ? 292  GLN A C     1 
ATOM   2322  O O     . GLN A 1 292 ? -36.997  -44.015  -12.563 1.00 22.80  ? 292  GLN A O     1 
ATOM   2323  C CB    . GLN A 1 292 ? -36.027  -41.081  -11.511 1.00 30.05  ? 292  GLN A CB    1 
ATOM   2324  C CG    . GLN A 1 292 ? -36.864  -39.846  -11.204 1.00 42.79  ? 292  GLN A CG    1 
ATOM   2325  C CD    . GLN A 1 292 ? -36.117  -38.558  -11.514 1.00 54.24  ? 292  GLN A CD    1 
ATOM   2326  O OE1   . GLN A 1 292 ? -35.945  -37.685  -10.655 1.00 49.69  ? 292  GLN A OE1   1 
ATOM   2327  N NE2   . GLN A 1 292 ? -35.603  -38.432  -12.731 1.00 55.42  ? 292  GLN A NE2   1 
ATOM   2328  N N     . THR A 1 293 ? -34.965  -44.155  -11.594 1.00 20.43  ? 293  THR A N     1 
ATOM   2329  C CA    . THR A 1 293 ? -34.553  -45.300  -12.385 1.00 21.44  ? 293  THR A CA    1 
ATOM   2330  C C     . THR A 1 293 ? -35.526  -46.455  -12.157 1.00 21.34  ? 293  THR A C     1 
ATOM   2331  O O     . THR A 1 293 ? -36.001  -47.062  -13.119 1.00 25.05  ? 293  THR A O     1 
ATOM   2332  C CB    . THR A 1 293 ? -33.100  -45.692  -12.056 1.00 21.32  ? 293  THR A CB    1 
ATOM   2333  O OG1   . THR A 1 293 ? -32.282  -44.681  -12.644 1.00 21.53  ? 293  THR A OG1   1 
ATOM   2334  C CG2   . THR A 1 293 ? -32.724  -47.062  -12.611 1.00 19.89  ? 293  THR A CG2   1 
ATOM   2335  N N     . TYR A 1 294 ? -35.829  -46.763  -10.888 1.00 18.65  ? 294  TYR A N     1 
ATOM   2336  C CA    . TYR A 1 294 ? -36.728  -47.863  -10.558 1.00 19.49  ? 294  TYR A CA    1 
ATOM   2337  C C     . TYR A 1 294 ? -38.126  -47.595  -11.117 1.00 22.18  ? 294  TYR A C     1 
ATOM   2338  O O     . TYR A 1 294 ? -38.766  -48.518  -11.630 1.00 23.35  ? 294  TYR A O     1 
ATOM   2339  C CB    . TYR A 1 294 ? -36.760  -48.154  -9.052  1.00 16.94  ? 294  TYR A CB    1 
ATOM   2340  C CG    . TYR A 1 294 ? -35.550  -48.964  -8.624  1.00 19.02  ? 294  TYR A CG    1 
ATOM   2341  C CD1   . TYR A 1 294 ? -34.281  -48.396  -8.572  1.00 19.48  ? 294  TYR A CD1   1 
ATOM   2342  C CD2   . TYR A 1 294 ? -35.684  -50.306  -8.269  1.00 19.73  ? 294  TYR A CD2   1 
ATOM   2343  C CE1   . TYR A 1 294 ? -33.181  -49.130  -8.153  1.00 22.62  ? 294  TYR A CE1   1 
ATOM   2344  C CE2   . TYR A 1 294 ? -34.591  -51.071  -7.892  1.00 20.94  ? 294  TYR A CE2   1 
ATOM   2345  C CZ    . TYR A 1 294 ? -33.342  -50.470  -7.809  1.00 23.92  ? 294  TYR A CZ    1 
ATOM   2346  O OH    . TYR A 1 294 ? -32.246  -51.192  -7.444  1.00 21.49  ? 294  TYR A OH    1 
ATOM   2347  N N     . MET A 1 295 ? -38.585  -46.334  -11.021 1.00 20.65  ? 295  MET A N     1 
ATOM   2348  C CA    . MET A 1 295 ? -39.901  -45.993  -11.547 1.00 22.38  ? 295  MET A CA    1 
ATOM   2349  C C     . MET A 1 295 ? -39.981  -46.184  -13.067 1.00 21.27  ? 295  MET A C     1 
ATOM   2350  O O     . MET A 1 295 ? -40.989  -46.695  -13.551 1.00 21.55  ? 295  MET A O     1 
ATOM   2351  C CB    . MET A 1 295 ? -40.316  -44.574  -11.144 1.00 21.16  ? 295  MET A CB    1 
ATOM   2352  C CG    . MET A 1 295 ? -40.613  -44.481  -9.647  1.00 25.30  ? 295  MET A CG    1 
ATOM   2353  S SD    . MET A 1 295 ? -40.756  -42.755  -9.105  1.00 32.40  ? 295  MET A SD    1 
ATOM   2354  C CE    . MET A 1 295 ? -42.437  -42.576  -9.768  1.00 32.83  ? 295  MET A CE    1 
ATOM   2355  N N     . HIS A 1 296 ? -38.943  -45.772  -13.816 1.00 20.04  ? 296  HIS A N     1 
ATOM   2356  C CA    . HIS A 1 296 ? -38.915  -45.964  -15.261 1.00 21.96  ? 296  HIS A CA    1 
ATOM   2357  C C     . HIS A 1 296 ? -39.013  -47.454  -15.621 1.00 20.50  ? 296  HIS A C     1 
ATOM   2358  O O     . HIS A 1 296 ? -39.792  -47.819  -16.501 1.00 24.60  ? 296  HIS A O     1 
ATOM   2359  C CB    . HIS A 1 296 ? -37.726  -45.255  -15.931 1.00 23.49  ? 296  HIS A CB    1 
ATOM   2360  C CG    . HIS A 1 296 ? -37.927  -43.783  -16.026 1.00 38.81  ? 296  HIS A CG    1 
ATOM   2361  N ND1   . HIS A 1 296 ? -37.094  -42.812  -15.507 1.00 47.47  ? 296  HIS A ND1   1 
ATOM   2362  C CD2   . HIS A 1 296 ? -38.866  -43.118  -16.659 1.00 45.30  ? 296  HIS A CD2   1 
ATOM   2363  C CE1   . HIS A 1 296 ? -37.578  -41.615  -15.737 1.00 41.03  ? 296  HIS A CE1   1 
ATOM   2364  N NE2   . HIS A 1 296 ? -38.627  -41.765  -16.476 1.00 41.28  ? 296  HIS A NE2   1 
ATOM   2365  N N     . LEU A 1 297 ? -38.243  -48.304  -14.937 1.00 18.98  ? 297  LEU A N     1 
ATOM   2366  C CA    . LEU A 1 297 ? -38.233  -49.726  -15.238 1.00 21.20  ? 297  LEU A CA    1 
ATOM   2367  C C     . LEU A 1 297 ? -39.598  -50.319  -14.885 1.00 22.90  ? 297  LEU A C     1 
ATOM   2368  O O     . LEU A 1 297 ? -40.182  -51.025  -15.709 1.00 25.38  ? 297  LEU A O     1 
ATOM   2369  C CB    . LEU A 1 297 ? -37.087  -50.484  -14.572 1.00 19.77  ? 297  LEU A CB    1 
ATOM   2370  C CG    . LEU A 1 297 ? -35.686  -50.011  -14.985 1.00 19.60  ? 297  LEU A CG    1 
ATOM   2371  C CD1   . LEU A 1 297 ? -34.623  -50.592  -14.048 1.00 19.12  ? 297  LEU A CD1   1 
ATOM   2372  C CD2   . LEU A 1 297 ? -35.303  -50.264  -16.417 1.00 17.36  ? 297  LEU A CD2   1 
ATOM   2373  N N     . LEU A 1 298 ? -40.131  -50.006  -13.693 1.00 19.37  ? 298  LEU A N     1 
ATOM   2374  C CA    . LEU A 1 298 ? -41.422  -50.548  -13.307 1.00 18.80  ? 298  LEU A CA    1 
ATOM   2375  C C     . LEU A 1 298 ? -42.490  -50.097  -14.311 1.00 19.65  ? 298  LEU A C     1 
ATOM   2376  O O     . LEU A 1 298 ? -43.353  -50.881  -14.686 1.00 21.25  ? 298  LEU A O     1 
ATOM   2377  C CB    . LEU A 1 298 ? -41.749  -50.046  -11.900 1.00 20.28  ? 298  LEU A CB    1 
ATOM   2378  C CG    . LEU A 1 298 ? -43.120  -50.460  -11.366 1.00 21.75  ? 298  LEU A CG    1 
ATOM   2379  C CD1   . LEU A 1 298 ? -43.230  -51.961  -11.372 1.00 19.87  ? 298  LEU A CD1   1 
ATOM   2380  C CD2   . LEU A 1 298 ? -43.304  -49.942  -9.962  1.00 23.66  ? 298  LEU A CD2   1 
ATOM   2381  N N     . GLY A 1 299 ? -42.398  -48.831  -14.762 1.00 19.03  ? 299  GLY A N     1 
ATOM   2382  C CA    . GLY A 1 299 ? -43.337  -48.243  -15.702 1.00 18.43  ? 299  GLY A CA    1 
ATOM   2383  C C     . GLY A 1 299 ? -43.390  -49.027  -17.020 1.00 21.15  ? 299  GLY A C     1 
ATOM   2384  O O     . GLY A 1 299 ? -44.467  -49.192  -17.596 1.00 21.62  ? 299  GLY A O     1 
ATOM   2385  N N     . ARG A 1 300 ? -42.240  -49.518  -17.495 1.00 17.87  ? 300  ARG A N     1 
ATOM   2386  C CA    . ARG A 1 300 ? -42.257  -50.261  -18.739 1.00 20.64  ? 300  ARG A CA    1 
ATOM   2387  C C     . ARG A 1 300 ? -43.008  -51.580  -18.500 1.00 21.50  ? 300  ARG A C     1 
ATOM   2388  O O     . ARG A 1 300 ? -43.777  -52.005  -19.356 1.00 19.77  ? 300  ARG A O     1 
ATOM   2389  C CB    . ARG A 1 300 ? -40.850  -50.538  -19.270 1.00 19.68  ? 300  ARG A CB    1 
ATOM   2390  C CG    . ARG A 1 300 ? -40.231  -49.293  -19.863 1.00 23.14  ? 300  ARG A CG    1 
ATOM   2391  C CD    . ARG A 1 300 ? -38.754  -49.614  -20.015 1.00 25.31  ? 300  ARG A CD    1 
ATOM   2392  N NE    . ARG A 1 300 ? -38.069  -48.499  -20.676 1.00 28.11  ? 300  ARG A NE    1 
ATOM   2393  C CZ    . ARG A 1 300 ? -38.223  -48.217  -21.978 1.00 31.11  ? 300  ARG A CZ    1 
ATOM   2394  N NH1   . ARG A 1 300 ? -38.830  -49.048  -22.816 1.00 26.23  ? 300  ARG A NH1   1 
ATOM   2395  N NH2   . ARG A 1 300 ? -37.687  -47.125  -22.462 1.00 28.87  ? 300  ARG A NH2   1 
ATOM   2396  N N     . TRP A 1 301 ? -42.830  -52.186  -17.316 1.00 19.31  ? 301  TRP A N     1 
ATOM   2397  C CA    . TRP A 1 301 ? -43.508  -53.442  -17.051 1.00 18.91  ? 301  TRP A CA    1 
ATOM   2398  C C     . TRP A 1 301 ? -45.020  -53.224  -16.901 1.00 20.84  ? 301  TRP A C     1 
ATOM   2399  O O     . TRP A 1 301 ? -45.820  -54.002  -17.455 1.00 20.28  ? 301  TRP A O     1 
ATOM   2400  C CB    . TRP A 1 301 ? -42.921  -54.165  -15.833 1.00 16.18  ? 301  TRP A CB    1 
ATOM   2401  C CG    . TRP A 1 301 ? -43.492  -55.549  -15.666 1.00 18.18  ? 301  TRP A CG    1 
ATOM   2402  C CD1   . TRP A 1 301 ? -43.044  -56.692  -16.278 1.00 16.06  ? 301  TRP A CD1   1 
ATOM   2403  C CD2   . TRP A 1 301 ? -44.638  -55.932  -14.863 1.00 15.55  ? 301  TRP A CD2   1 
ATOM   2404  N NE1   . TRP A 1 301 ? -43.823  -57.755  -15.895 1.00 18.04  ? 301  TRP A NE1   1 
ATOM   2405  C CE2   . TRP A 1 301 ? -44.817  -57.319  -15.049 1.00 16.39  ? 301  TRP A CE2   1 
ATOM   2406  C CE3   . TRP A 1 301 ? -45.514  -55.247  -14.013 1.00 15.85  ? 301  TRP A CE3   1 
ATOM   2407  C CZ2   . TRP A 1 301 ? -45.830  -58.039  -14.404 1.00 17.86  ? 301  TRP A CZ2   1 
ATOM   2408  C CZ3   . TRP A 1 301 ? -46.507  -55.960  -13.359 1.00 15.72  ? 301  TRP A CZ3   1 
ATOM   2409  C CH2   . TRP A 1 301 ? -46.672  -57.335  -13.553 1.00 16.49  ? 301  TRP A CH2   1 
ATOM   2410  N N     . THR A 1 302 ? -45.421  -52.187  -16.140 1.00 19.16  ? 302  THR A N     1 
ATOM   2411  C CA    . THR A 1 302 ? -46.835  -52.050  -15.840 1.00 17.42  ? 302  THR A CA    1 
ATOM   2412  C C     . THR A 1 302 ? -47.578  -51.621  -17.100 1.00 19.58  ? 302  THR A C     1 
ATOM   2413  O O     . THR A 1 302 ? -48.743  -51.984  -17.262 1.00 22.08  ? 302  THR A O     1 
ATOM   2414  C CB    . THR A 1 302 ? -47.089  -51.100  -14.668 1.00 18.03  ? 302  THR A CB    1 
ATOM   2415  O OG1   . THR A 1 302 ? -46.634  -49.833  -15.134 1.00 17.50  ? 302  THR A OG1   1 
ATOM   2416  C CG2   . THR A 1 302 ? -46.420  -51.522  -13.371 1.00 14.72  ? 302  THR A CG2   1 
ATOM   2417  N N     . ALA A 1 303 ? -46.934  -50.858  -17.999 1.00 19.02  ? 303  ALA A N     1 
ATOM   2418  C CA    . ALA A 1 303 ? -47.592  -50.523  -19.272 1.00 20.60  ? 303  ALA A CA    1 
ATOM   2419  C C     . ALA A 1 303 ? -47.909  -51.806  -20.045 1.00 22.34  ? 303  ALA A C     1 
ATOM   2420  O O     . ALA A 1 303 ? -49.004  -51.959  -20.567 1.00 24.20  ? 303  ALA A O     1 
ATOM   2421  C CB    . ALA A 1 303 ? -46.789  -49.522  -20.135 1.00 12.96  ? 303  ALA A CB    1 
ATOM   2422  N N     . MET A 1 304 ? -46.951  -52.747  -20.093 1.00 22.71  ? 304  MET A N     1 
ATOM   2423  C CA    . MET A 1 304 ? -47.169  -54.007  -20.794 1.00 19.42  ? 304  MET A CA    1 
ATOM   2424  C C     . MET A 1 304 ? -48.279  -54.794  -20.079 1.00 22.29  ? 304  MET A C     1 
ATOM   2425  O O     . MET A 1 304 ? -49.114  -55.396  -20.749 1.00 24.25  ? 304  MET A O     1 
ATOM   2426  C CB    . MET A 1 304 ? -45.838  -54.758  -20.902 1.00 16.95  ? 304  MET A CB    1 
ATOM   2427  C CG    . MET A 1 304 ? -45.909  -56.188  -21.432 1.00 18.71  ? 304  MET A CG    1 
ATOM   2428  S SD    . MET A 1 304 ? -46.477  -57.393  -20.217 1.00 22.82  ? 304  MET A SD    1 
ATOM   2429  C CE    . MET A 1 304 ? -45.142  -57.484  -19.004 1.00 17.52  ? 304  MET A CE    1 
ATOM   2430  N N     . ALA A 1 305 ? -48.307  -54.772  -18.728 1.00 20.98  ? 305  ALA A N     1 
ATOM   2431  C CA    . ALA A 1 305 ? -49.195  -55.624  -17.946 1.00 20.27  ? 305  ALA A CA    1 
ATOM   2432  C C     . ALA A 1 305 ? -50.589  -55.015  -17.724 1.00 21.99  ? 305  ALA A C     1 
ATOM   2433  O O     . ALA A 1 305 ? -51.433  -55.643  -17.073 1.00 23.96  ? 305  ALA A O     1 
ATOM   2434  C CB    . ALA A 1 305 ? -48.566  -55.931  -16.591 1.00 19.50  ? 305  ALA A CB    1 
ATOM   2435  N N     . ALA A 1 306 ? -50.829  -53.797  -18.235 1.00 21.28  ? 306  ALA A N     1 
ATOM   2436  C CA    . ALA A 1 306 ? -52.082  -53.053  -18.050 1.00 22.30  ? 306  ALA A CA    1 
ATOM   2437  C C     . ALA A 1 306 ? -53.358  -53.897  -18.222 1.00 23.84  ? 306  ALA A C     1 
ATOM   2438  O O     . ALA A 1 306 ? -54.322  -53.714  -17.469 1.00 23.72  ? 306  ALA A O     1 
ATOM   2439  C CB    . ALA A 1 306 ? -52.130  -51.808  -18.915 1.00 17.88  ? 306  ALA A CB    1 
ATOM   2440  N N     . PRO A 1 307 ? -53.477  -54.822  -19.212 1.00 22.68  ? 307  PRO A N     1 
ATOM   2441  C CA    . PRO A 1 307 ? -54.724  -55.582  -19.349 1.00 21.34  ? 307  PRO A CA    1 
ATOM   2442  C C     . PRO A 1 307 ? -55.069  -56.412  -18.118 1.00 22.52  ? 307  PRO A C     1 
ATOM   2443  O O     . PRO A 1 307 ? -56.218  -56.784  -17.975 1.00 27.25  ? 307  PRO A O     1 
ATOM   2444  C CB    . PRO A 1 307 ? -54.546  -56.437  -20.613 1.00 17.92  ? 307  PRO A CB    1 
ATOM   2445  C CG    . PRO A 1 307 ? -53.459  -55.699  -21.387 1.00 20.42  ? 307  PRO A CG    1 
ATOM   2446  C CD    . PRO A 1 307 ? -52.537  -55.078  -20.316 1.00 21.42  ? 307  PRO A CD    1 
ATOM   2447  N N     . VAL A 1 308 ? -54.106  -56.717  -17.236 1.00 21.26  ? 308  VAL A N     1 
ATOM   2448  C CA    . VAL A 1 308 ? -54.396  -57.638  -16.140 1.00 20.95  ? 308  VAL A CA    1 
ATOM   2449  C C     . VAL A 1 308 ? -54.070  -57.021  -14.770 1.00 21.36  ? 308  VAL A C     1 
ATOM   2450  O O     . VAL A 1 308 ? -54.602  -57.458  -13.758 1.00 21.02  ? 308  VAL A O     1 
ATOM   2451  C CB    . VAL A 1 308 ? -53.698  -59.010  -16.332 1.00 21.49  ? 308  VAL A CB    1 
ATOM   2452  C CG1   . VAL A 1 308 ? -52.169  -58.899  -16.233 1.00 18.91  ? 308  VAL A CG1   1 
ATOM   2453  C CG2   . VAL A 1 308 ? -54.202  -60.010  -15.305 1.00 18.27  ? 308  VAL A CG2   1 
ATOM   2454  N N     . LEU A 1 309 ? -53.175  -56.026  -14.722 1.00 20.39  ? 309  LEU A N     1 
ATOM   2455  C CA    . LEU A 1 309 ? -52.660  -55.583  -13.435 1.00 22.32  ? 309  LEU A CA    1 
ATOM   2456  C C     . LEU A 1 309 ? -53.794  -55.060  -12.525 1.00 25.71  ? 309  LEU A C     1 
ATOM   2457  O O     . LEU A 1 309 ? -53.714  -55.223  -11.311 1.00 22.07  ? 309  LEU A O     1 
ATOM   2458  C CB    . LEU A 1 309 ? -51.628  -54.476  -13.697 1.00 24.92  ? 309  LEU A CB    1 
ATOM   2459  C CG    . LEU A 1 309 ? -51.004  -53.824  -12.464 1.00 22.00  ? 309  LEU A CG    1 
ATOM   2460  C CD1   . LEU A 1 309 ? -50.262  -54.821  -11.610 1.00 20.52  ? 309  LEU A CD1   1 
ATOM   2461  C CD2   . LEU A 1 309 ? -50.087  -52.706  -12.971 1.00 21.76  ? 309  LEU A CD2   1 
ATOM   2462  N N     . TYR A 1 310 ? -54.809  -54.370  -13.092 1.00 22.91  ? 310  TYR A N     1 
ATOM   2463  C CA    . TYR A 1 310 ? -55.867  -53.728  -12.323 1.00 23.56  ? 310  TYR A CA    1 
ATOM   2464  C C     . TYR A 1 310 ? -57.029  -54.683  -12.015 1.00 25.50  ? 310  TYR A C     1 
ATOM   2465  O O     . TYR A 1 310 ? -57.416  -54.829  -10.850 1.00 24.36  ? 310  TYR A O     1 
ATOM   2466  C CB    . TYR A 1 310 ? -56.322  -52.428  -13.001 1.00 22.34  ? 310  TYR A CB    1 
ATOM   2467  C CG    . TYR A 1 310 ? -55.093  -51.586  -13.281 1.00 21.89  ? 310  TYR A CG    1 
ATOM   2468  C CD1   . TYR A 1 310 ? -54.366  -51.032  -12.222 1.00 19.31  ? 310  TYR A CD1   1 
ATOM   2469  C CD2   . TYR A 1 310 ? -54.607  -51.425  -14.585 1.00 18.24  ? 310  TYR A CD2   1 
ATOM   2470  C CE1   . TYR A 1 310 ? -53.200  -50.321  -12.479 1.00 19.93  ? 310  TYR A CE1   1 
ATOM   2471  C CE2   . TYR A 1 310 ? -53.470  -50.672  -14.843 1.00 16.23  ? 310  TYR A CE2   1 
ATOM   2472  C CZ    . TYR A 1 310 ? -52.759  -50.132  -13.786 1.00 18.71  ? 310  TYR A CZ    1 
ATOM   2473  O OH    . TYR A 1 310 ? -51.606  -49.423  -14.001 1.00 22.04  ? 310  TYR A OH    1 
ATOM   2474  N N     . LYS A 1 311 ? -57.555  -55.359  -13.048 1.00 24.87  ? 311  LYS A N     1 
ATOM   2475  C CA    . LYS A 1 311 ? -58.753  -56.173  -12.884 1.00 25.00  ? 311  LYS A CA    1 
ATOM   2476  C C     . LYS A 1 311 ? -58.441  -57.631  -12.562 1.00 25.45  ? 311  LYS A C     1 
ATOM   2477  O O     . LYS A 1 311 ? -59.347  -58.340  -12.165 1.00 31.81  ? 311  LYS A O     1 
ATOM   2478  C CB    . LYS A 1 311 ? -59.517  -56.141  -14.214 1.00 27.15  ? 311  LYS A CB    1 
ATOM   2479  C CG    . LYS A 1 311 ? -60.021  -54.761  -14.602 1.00 32.08  ? 311  LYS A CG    1 
ATOM   2480  C CD    . LYS A 1 311 ? -61.147  -54.324  -13.661 1.00 38.35  ? 311  LYS A CD    1 
ATOM   2481  C CE    . LYS A 1 311 ? -61.684  -52.985  -14.088 1.00 44.03  ? 311  LYS A CE    1 
ATOM   2482  N NZ    . LYS A 1 311 ? -62.795  -52.684  -13.191 1.00 46.56  ? 311  LYS A NZ    1 
ATOM   2483  N N     . GLY A 1 312 ? -57.189  -58.093  -12.753 1.00 22.52  ? 312  GLY A N     1 
ATOM   2484  C CA    . GLY A 1 312 ? -56.849  -59.491  -12.544 1.00 19.20  ? 312  GLY A CA    1 
ATOM   2485  C C     . GLY A 1 312 ? -57.019  -59.891  -11.074 1.00 19.31  ? 312  GLY A C     1 
ATOM   2486  O O     . GLY A 1 312 ? -56.656  -59.152  -10.167 1.00 21.84  ? 312  GLY A O     1 
ATOM   2487  N N     . ARG A 1 313 ? -57.538  -61.095  -10.846 1.00 19.73  ? 313  ARG A N     1 
ATOM   2488  C CA    . ARG A 1 313 ? -57.795  -61.589  -9.498  1.00 21.60  ? 313  ARG A CA    1 
ATOM   2489  C C     . ARG A 1 313 ? -57.285  -63.018  -9.393  1.00 22.69  ? 313  ARG A C     1 
ATOM   2490  O O     . ARG A 1 313 ? -57.248  -63.737  -10.398 1.00 23.53  ? 313  ARG A O     1 
ATOM   2491  C CB    . ARG A 1 313 ? -59.301  -61.586  -9.165  1.00 18.71  ? 313  ARG A CB    1 
ATOM   2492  C CG    . ARG A 1 313 ? -59.893  -60.189  -9.063  1.00 17.68  ? 313  ARG A CG    1 
ATOM   2493  C CD    . ARG A 1 313 ? -59.293  -59.426  -7.853  1.00 17.93  ? 313  ARG A CD    1 
ATOM   2494  N NE    . ARG A 1 313 ? -59.870  -58.079  -7.722  1.00 22.04  ? 313  ARG A NE    1 
ATOM   2495  C CZ    . ARG A 1 313 ? -59.513  -56.982  -8.429  1.00 21.26  ? 313  ARG A CZ    1 
ATOM   2496  N NH1   . ARG A 1 313 ? -58.472  -56.996  -9.258  1.00 22.17  ? 313  ARG A NH1   1 
ATOM   2497  N NH2   . ARG A 1 313 ? -60.186  -55.855  -8.273  1.00 21.55  ? 313  ARG A NH2   1 
ATOM   2498  N N     . PRO A 1 314 ? -56.916  -63.467  -8.174  1.00 25.24  ? 314  PRO A N     1 
ATOM   2499  C CA    . PRO A 1 314 ? -56.527  -64.856  -7.971  1.00 27.84  ? 314  PRO A CA    1 
ATOM   2500  C C     . PRO A 1 314 ? -57.645  -65.794  -8.386  1.00 30.86  ? 314  PRO A C     1 
ATOM   2501  O O     . PRO A 1 314 ? -58.814  -65.434  -8.270  1.00 28.75  ? 314  PRO A O     1 
ATOM   2502  C CB    . PRO A 1 314 ? -56.318  -64.991  -6.447  1.00 25.93  ? 314  PRO A CB    1 
ATOM   2503  C CG    . PRO A 1 314 ? -56.120  -63.549  -5.978  1.00 23.58  ? 314  PRO A CG    1 
ATOM   2504  C CD    . PRO A 1 314 ? -56.898  -62.671  -6.930  1.00 22.90  ? 314  PRO A CD    1 
ATOM   2505  N N     . VAL A 1 315 ? -57.283  -67.006  -8.820  1.00 29.85  ? 315  VAL A N     1 
ATOM   2506  C CA    . VAL A 1 315 ? -58.285  -67.966  -9.240  1.00 28.08  ? 315  VAL A CA    1 
ATOM   2507  C C     . VAL A 1 315 ? -57.703  -69.334  -8.884  1.00 33.35  ? 315  VAL A C     1 
ATOM   2508  O O     . VAL A 1 315 ? -56.485  -69.459  -8.812  1.00 31.05  ? 315  VAL A O     1 
ATOM   2509  C CB    . VAL A 1 315 ? -58.437  -67.695  -10.748 1.00 27.37  ? 315  VAL A CB    1 
ATOM   2510  C CG1   . VAL A 1 315 ? -57.214  -68.067  -11.588 1.00 23.07  ? 315  VAL A CG1   1 
ATOM   2511  C CG2   . VAL A 1 315 ? -59.680  -68.304  -11.358 1.00 26.92  ? 315  VAL A CG2   1 
ATOM   2512  N N     . PRO A 1 316 ? -58.517  -70.368  -8.561  1.00 35.62  ? 316  PRO A N     1 
ATOM   2513  C CA    . PRO A 1 316 ? -57.961  -71.661  -8.150  1.00 37.04  ? 316  PRO A CA    1 
ATOM   2514  C C     . PRO A 1 316 ? -57.363  -72.459  -9.323  1.00 35.98  ? 316  PRO A C     1 
ATOM   2515  O O     . PRO A 1 316 ? -57.927  -73.437  -9.782  1.00 41.47  ? 316  PRO A O     1 
ATOM   2516  C CB    . PRO A 1 316 ? -59.134  -72.327  -7.411  1.00 30.05  ? 316  PRO A CB    1 
ATOM   2517  C CG    . PRO A 1 316 ? -60.329  -71.782  -8.203  1.00 31.13  ? 316  PRO A CG    1 
ATOM   2518  C CD    . PRO A 1 316 ? -59.995  -70.366  -8.610  1.00 33.03  ? 316  PRO A CD    1 
ATOM   2519  N N     . VAL A 1 317 ? -56.265  -71.959  -9.886  1.00 37.16  ? 317  VAL A N     1 
ATOM   2520  C CA    . VAL A 1 317 ? -55.561  -72.589  -10.979 1.00 33.21  ? 317  VAL A CA    1 
ATOM   2521  C C     . VAL A 1 317 ? -54.115  -72.648  -10.529 1.00 36.00  ? 317  VAL A C     1 
ATOM   2522  O O     . VAL A 1 317 ? -53.552  -71.610  -10.205 1.00 41.03  ? 317  VAL A O     1 
ATOM   2523  C CB    . VAL A 1 317 ? -55.679  -71.834  -12.313 1.00 28.91  ? 317  VAL A CB    1 
ATOM   2524  C CG1   . VAL A 1 317 ? -54.838  -72.526  -13.392 1.00 25.39  ? 317  VAL A CG1   1 
ATOM   2525  C CG2   . VAL A 1 317 ? -57.129  -71.700  -12.775 1.00 24.30  ? 317  VAL A CG2   1 
ATOM   2526  N N     . THR A 1 318 ? -53.542  -73.852  -10.438 1.00 34.68  ? 318  THR A N     1 
ATOM   2527  C CA    . THR A 1 318 ? -52.179  -73.937  -9.941  1.00 33.11  ? 318  THR A CA    1 
ATOM   2528  C C     . THR A 1 318 ? -51.213  -74.263  -11.083 1.00 32.17  ? 318  THR A C     1 
ATOM   2529  O O     . THR A 1 318 ? -51.614  -74.695  -12.167 1.00 31.76  ? 318  THR A O     1 
ATOM   2530  C CB    . THR A 1 318 ? -52.075  -74.907  -8.766  1.00 35.09  ? 318  THR A CB    1 
ATOM   2531  O OG1   . THR A 1 318 ? -52.413  -76.185  -9.277  1.00 33.01  ? 318  THR A OG1   1 
ATOM   2532  C CG2   . THR A 1 318 ? -52.987  -74.539  -7.606  1.00 39.00  ? 318  THR A CG2   1 
ATOM   2533  N N     . SER A 1 319 ? -49.918  -74.060  -10.834 1.00 30.23  ? 319  SER A N     1 
ATOM   2534  C CA    . SER A 1 319 ? -48.929  -74.343  -11.857 1.00 27.80  ? 319  SER A CA    1 
ATOM   2535  C C     . SER A 1 319 ? -48.304  -75.703  -11.554 1.00 28.96  ? 319  SER A C     1 
ATOM   2536  O O     . SER A 1 319 ? -48.398  -76.202  -10.432 1.00 26.78  ? 319  SER A O     1 
ATOM   2537  C CB    . SER A 1 319 ? -47.903  -73.238  -11.923 1.00 29.19  ? 319  SER A CB    1 
ATOM   2538  O OG    . SER A 1 319 ? -47.068  -73.242  -10.774 1.00 35.87  ? 319  SER A OG    1 
ATOM   2539  N N     . ALA A 1 320 ? -47.658  -76.297  -12.552 1.00 27.46  ? 320  ALA A N     1 
ATOM   2540  C CA    . ALA A 1 320 ? -47.001  -77.586  -12.383 1.00 31.47  ? 320  ALA A CA    1 
ATOM   2541  C C     . ALA A 1 320 ? -45.863  -77.510  -11.362 1.00 29.23  ? 320  ALA A C     1 
ATOM   2542  O O     . ALA A 1 320 ? -45.305  -76.452  -11.114 1.00 28.92  ? 320  ALA A O     1 
ATOM   2543  C CB    . ALA A 1 320 ? -46.486  -78.040  -13.743 1.00 28.36  ? 320  ALA A CB    1 
ATOM   2544  N N     . HIS A 1 321 ? -45.472  -78.683  -10.868 1.00 28.77  ? 321  HIS A N     1 
ATOM   2545  C CA    . HIS A 1 321 ? -44.341  -78.907  -9.994  1.00 28.31  ? 321  HIS A CA    1 
ATOM   2546  C C     . HIS A 1 321 ? -43.101  -78.174  -10.498 1.00 30.50  ? 321  HIS A C     1 
ATOM   2547  O O     . HIS A 1 321 ? -42.707  -78.312  -11.655 1.00 29.41  ? 321  HIS A O     1 
ATOM   2548  C CB    . HIS A 1 321 ? -44.105  -80.415  -9.837  1.00 26.22  ? 321  HIS A CB    1 
ATOM   2549  C CG    . HIS A 1 321 ? -42.914  -80.714  -9.004  1.00 31.75  ? 321  HIS A CG    1 
ATOM   2550  N ND1   . HIS A 1 321 ? -42.910  -80.742  -7.623  1.00 32.86  ? 321  HIS A ND1   1 
ATOM   2551  C CD2   . HIS A 1 321 ? -41.647  -80.949  -9.397  1.00 30.96  ? 321  HIS A CD2   1 
ATOM   2552  C CE1   . HIS A 1 321 ? -41.683  -81.047  -7.209  1.00 34.73  ? 321  HIS A CE1   1 
ATOM   2553  N NE2   . HIS A 1 321 ? -40.888  -81.124  -8.264  1.00 31.57  ? 321  HIS A NE2   1 
ATOM   2554  N N     . GLY A 1 322 ? -42.487  -77.397  -9.588  1.00 33.10  ? 322  GLY A N     1 
ATOM   2555  C CA    . GLY A 1 322 ? -41.170  -76.821  -9.816  1.00 32.03  ? 322  GLY A CA    1 
ATOM   2556  C C     . GLY A 1 322 ? -41.180  -75.489  -10.580 1.00 36.20  ? 322  GLY A C     1 
ATOM   2557  O O     . GLY A 1 322 ? -40.112  -75.067  -11.039 1.00 37.39  ? 322  GLY A O     1 
ATOM   2558  N N     . THR A 1 323 ? -42.353  -74.857  -10.767 1.00 26.88  ? 323  THR A N     1 
ATOM   2559  C CA    . THR A 1 323 ? -42.394  -73.558  -11.418 1.00 27.71  ? 323  THR A CA    1 
ATOM   2560  C C     . THR A 1 323 ? -43.016  -72.581  -10.440 1.00 25.08  ? 323  THR A C     1 
ATOM   2561  O O     . THR A 1 323 ? -43.680  -73.007  -9.514  1.00 27.62  ? 323  THR A O     1 
ATOM   2562  C CB    . THR A 1 323 ? -43.117  -73.567  -12.776 1.00 24.52  ? 323  THR A CB    1 
ATOM   2563  O OG1   . THR A 1 323 ? -44.513  -73.515  -12.509 1.00 23.42  ? 323  THR A OG1   1 
ATOM   2564  C CG2   . THR A 1 323 ? -42.807  -74.794  -13.625 1.00 18.69  ? 323  THR A CG2   1 
ATOM   2565  N N     . ARG A 1 324 ? -42.822  -71.280  -10.679 1.00 30.26  ? 324  ARG A N     1 
ATOM   2566  C CA    . ARG A 1 324 ? -43.426  -70.242  -9.860  1.00 27.24  ? 324  ARG A CA    1 
ATOM   2567  C C     . ARG A 1 324 ? -44.500  -69.528  -10.681 1.00 25.79  ? 324  ARG A C     1 
ATOM   2568  O O     . ARG A 1 324 ? -44.937  -68.453  -10.310 1.00 27.43  ? 324  ARG A O     1 
ATOM   2569  C CB    . ARG A 1 324 ? -42.342  -69.228  -9.465  1.00 29.37  ? 324  ARG A CB    1 
ATOM   2570  C CG    . ARG A 1 324 ? -41.146  -69.838  -8.745  1.00 30.12  ? 324  ARG A CG    1 
ATOM   2571  C CD    . ARG A 1 324 ? -40.113  -68.838  -8.239  1.00 26.65  ? 324  ARG A CD    1 
ATOM   2572  N NE    . ARG A 1 324 ? -39.424  -68.128  -9.329  1.00 26.66  ? 324  ARG A NE    1 
ATOM   2573  C CZ    . ARG A 1 324 ? -39.086  -66.837  -9.323  1.00 23.64  ? 324  ARG A CZ    1 
ATOM   2574  N NH1   . ARG A 1 324 ? -39.489  -66.053  -8.341  1.00 20.01  ? 324  ARG A NH1   1 
ATOM   2575  N NH2   . ARG A 1 324 ? -38.327  -66.327  -10.289 1.00 20.57  ? 324  ARG A NH2   1 
ATOM   2576  N N     . ASP A 1 325 ? -44.916  -70.104  -11.812 1.00 21.65  ? 325  ASP A N     1 
ATOM   2577  C CA    . ASP A 1 325 ? -45.928  -69.499  -12.666 1.00 20.22  ? 325  ASP A CA    1 
ATOM   2578  C C     . ASP A 1 325 ? -47.275  -69.419  -11.930 1.00 22.78  ? 325  ASP A C     1 
ATOM   2579  O O     . ASP A 1 325 ? -47.550  -70.211  -11.017 1.00 24.90  ? 325  ASP A O     1 
ATOM   2580  C CB    . ASP A 1 325 ? -46.004  -70.302  -13.950 1.00 22.22  ? 325  ASP A CB    1 
ATOM   2581  C CG    . ASP A 1 325 ? -44.675  -70.485  -14.684 1.00 32.23  ? 325  ASP A CG    1 
ATOM   2582  O OD1   . ASP A 1 325 ? -43.708  -69.664  -14.458 1.00 31.61  ? 325  ASP A OD1   1 
ATOM   2583  O OD2   . ASP A 1 325 ? -44.586  -71.476  -15.475 1.00 31.52  ? 325  ASP A OD2   1 
ATOM   2584  N N     . PHE A 1 326 ? -48.155  -68.495  -12.337 1.00 22.29  ? 326  PHE A N     1 
ATOM   2585  C CA    . PHE A 1 326 ? -49.477  -68.405  -11.713 1.00 21.88  ? 326  PHE A CA    1 
ATOM   2586  C C     . PHE A 1 326 ? -50.461  -67.803  -12.711 1.00 20.91  ? 326  PHE A C     1 
ATOM   2587  O O     . PHE A 1 326 ? -50.048  -67.337  -13.783 1.00 22.54  ? 326  PHE A O     1 
ATOM   2588  C CB    . PHE A 1 326 ? -49.443  -67.622  -10.387 1.00 21.98  ? 326  PHE A CB    1 
ATOM   2589  C CG    . PHE A 1 326 ? -49.002  -66.167  -10.537 1.00 26.95  ? 326  PHE A CG    1 
ATOM   2590  C CD1   . PHE A 1 326 ? -49.930  -65.150  -10.804 1.00 25.67  ? 326  PHE A CD1   1 
ATOM   2591  C CD2   . PHE A 1 326 ? -47.651  -65.806  -10.400 1.00 23.16  ? 326  PHE A CD2   1 
ATOM   2592  C CE1   . PHE A 1 326 ? -49.513  -63.816  -10.911 1.00 26.93  ? 326  PHE A CE1   1 
ATOM   2593  C CE2   . PHE A 1 326 ? -47.241  -64.478  -10.527 1.00 25.68  ? 326  PHE A CE2   1 
ATOM   2594  C CZ    . PHE A 1 326 ? -48.170  -63.476  -10.782 1.00 25.23  ? 326  PHE A CZ    1 
ATOM   2595  N N     . VAL A 1 327 ? -51.747  -67.785  -12.348 1.00 19.68  ? 327  VAL A N     1 
ATOM   2596  C CA    . VAL A 1 327 ? -52.793  -67.317  -13.252 1.00 20.05  ? 327  VAL A CA    1 
ATOM   2597  C C     . VAL A 1 327 ? -53.608  -66.198  -12.595 1.00 23.39  ? 327  VAL A C     1 
ATOM   2598  O O     . VAL A 1 327 ? -53.883  -66.253  -11.396 1.00 22.42  ? 327  VAL A O     1 
ATOM   2599  C CB    . VAL A 1 327 ? -53.703  -68.513  -13.590 1.00 19.89  ? 327  VAL A CB    1 
ATOM   2600  C CG1   . VAL A 1 327 ? -54.823  -68.128  -14.559 1.00 17.32  ? 327  VAL A CG1   1 
ATOM   2601  C CG2   . VAL A 1 327 ? -52.874  -69.676  -14.130 1.00 16.35  ? 327  VAL A CG2   1 
ATOM   2602  N N     . LEU A 1 328 ? -53.977  -65.176  -13.396 1.00 21.73  ? 328  LEU A N     1 
ATOM   2603  C CA    . LEU A 1 328 ? -54.910  -64.153  -12.949 1.00 21.81  ? 328  LEU A CA    1 
ATOM   2604  C C     . LEU A 1 328 ? -56.144  -64.164  -13.854 1.00 24.17  ? 328  LEU A C     1 
ATOM   2605  O O     . LEU A 1 328 ? -56.046  -64.372  -15.069 1.00 28.31  ? 328  LEU A O     1 
ATOM   2606  C CB    . LEU A 1 328 ? -54.203  -62.799  -12.972 1.00 19.64  ? 328  LEU A CB    1 
ATOM   2607  C CG    . LEU A 1 328 ? -53.088  -62.590  -11.935 1.00 19.75  ? 328  LEU A CG    1 
ATOM   2608  C CD1   . LEU A 1 328 ? -52.292  -61.302  -12.206 1.00 19.71  ? 328  LEU A CD1   1 
ATOM   2609  C CD2   . LEU A 1 328 ? -53.671  -62.668  -10.517 1.00 17.42  ? 328  LEU A CD2   1 
ATOM   2610  N N     . HIS A 1 329 ? -57.303  -63.902  -13.255 1.00 25.63  ? 329  HIS A N     1 
ATOM   2611  C CA    . HIS A 1 329 ? -58.592  -63.967  -13.936 1.00 25.93  ? 329  HIS A CA    1 
ATOM   2612  C C     . HIS A 1 329 ? -59.201  -62.567  -14.046 1.00 25.53  ? 329  HIS A C     1 
ATOM   2613  O O     . HIS A 1 329 ? -59.207  -61.811  -13.074 1.00 26.64  ? 329  HIS A O     1 
ATOM   2614  C CB    . HIS A 1 329 ? -59.496  -64.922  -13.146 1.00 28.74  ? 329  HIS A CB    1 
ATOM   2615  C CG    . HIS A 1 329 ? -60.899  -64.970  -13.612 1.00 34.28  ? 329  HIS A CG    1 
ATOM   2616  N ND1   . HIS A 1 329 ? -61.289  -65.705  -14.724 1.00 32.57  ? 329  HIS A ND1   1 
ATOM   2617  C CD2   . HIS A 1 329 ? -62.002  -64.361  -13.130 1.00 36.18  ? 329  HIS A CD2   1 
ATOM   2618  C CE1   . HIS A 1 329 ? -62.595  -65.540  -14.918 1.00 33.47  ? 329  HIS A CE1   1 
ATOM   2619  N NE2   . HIS A 1 329 ? -63.047  -64.726  -13.966 1.00 41.63  ? 329  HIS A NE2   1 
ATOM   2620  N N     . THR A 1 330 ? -59.653  -62.194  -15.242 1.00 25.72  ? 330  THR A N     1 
ATOM   2621  C CA    . THR A 1 330 ? -60.595  -61.093  -15.400 1.00 30.79  ? 330  THR A CA    1 
ATOM   2622  C C     . THR A 1 330 ? -61.882  -61.693  -15.951 1.00 34.08  ? 330  THR A C     1 
ATOM   2623  O O     . THR A 1 330 ? -61.940  -62.895  -16.199 1.00 37.46  ? 330  THR A O     1 
ATOM   2624  C CB    . THR A 1 330 ? -60.063  -59.973  -16.294 1.00 27.39  ? 330  THR A CB    1 
ATOM   2625  O OG1   . THR A 1 330 ? -60.023  -60.533  -17.612 1.00 31.63  ? 330  THR A OG1   1 
ATOM   2626  C CG2   . THR A 1 330 ? -58.704  -59.465  -15.841 1.00 24.05  ? 330  THR A CG2   1 
ATOM   2627  N N     . SER A 1 331 ? -62.930  -60.891  -16.134 1.00 38.15  ? 331  SER A N     1 
ATOM   2628  C CA    . SER A 1 331 ? -64.183  -61.536  -16.531 1.00 43.37  ? 331  SER A CA    1 
ATOM   2629  C C     . SER A 1 331 ? -64.109  -62.010  -17.990 1.00 40.17  ? 331  SER A C     1 
ATOM   2630  O O     . SER A 1 331 ? -64.800  -62.945  -18.333 1.00 42.05  ? 331  SER A O     1 
ATOM   2631  C CB    . SER A 1 331 ? -65.408  -60.692  -16.269 1.00 36.58  ? 331  SER A CB    1 
ATOM   2632  O OG    . SER A 1 331 ? -65.241  -59.503  -17.035 1.00 42.95  ? 331  SER A OG    1 
ATOM   2633  N N     . LYS A 1 332 ? -63.232  -61.424  -18.814 1.00 38.36  ? 332  LYS A N     1 
ATOM   2634  C CA    . LYS A 1 332 ? -63.121  -61.806  -20.214 1.00 42.95  ? 332  LYS A CA    1 
ATOM   2635  C C     . LYS A 1 332 ? -61.974  -62.774  -20.510 1.00 42.88  ? 332  LYS A C     1 
ATOM   2636  O O     . LYS A 1 332 ? -62.037  -63.466  -21.521 1.00 38.14  ? 332  LYS A O     1 
ATOM   2637  C CB    . LYS A 1 332 ? -63.071  -60.541  -21.080 1.00 59.99  ? 332  LYS A CB    1 
ATOM   2638  C CG    . LYS A 1 332 ? -64.480  -60.163  -21.497 1.00 78.75  ? 332  LYS A CG    1 
ATOM   2639  C CD    . LYS A 1 332 ? -64.984  -58.715  -21.571 1.00 89.34  ? 332  LYS A CD    1 
ATOM   2640  C CE    . LYS A 1 332 ? -66.486  -58.824  -21.573 1.00 95.69  ? 332  LYS A CE    1 
ATOM   2641  N NZ    . LYS A 1 332 ? -67.213  -57.854  -20.739 1.00 95.49  ? 332  LYS A NZ    1 
ATOM   2642  N N     . HIS A 1 333 ? -60.928  -62.828  -19.660 1.00 38.76  ? 333  HIS A N     1 
ATOM   2643  C CA    . HIS A 1 333 ? -59.739  -63.585  -20.003 1.00 31.06  ? 333  HIS A CA    1 
ATOM   2644  C C     . HIS A 1 333 ? -59.075  -64.167  -18.764 1.00 31.45  ? 333  HIS A C     1 
ATOM   2645  O O     . HIS A 1 333 ? -59.265  -63.692  -17.646 1.00 30.98  ? 333  HIS A O     1 
ATOM   2646  C CB    . HIS A 1 333 ? -58.726  -62.704  -20.723 1.00 32.18  ? 333  HIS A CB    1 
ATOM   2647  C CG    . HIS A 1 333 ? -59.199  -62.081  -21.994 1.00 35.51  ? 333  HIS A CG    1 
ATOM   2648  N ND1   . HIS A 1 333 ? -59.339  -62.776  -23.182 1.00 35.49  ? 333  HIS A ND1   1 
ATOM   2649  C CD2   . HIS A 1 333 ? -59.556  -60.820  -22.264 1.00 32.64  ? 333  HIS A CD2   1 
ATOM   2650  C CE1   . HIS A 1 333 ? -59.782  -61.961  -24.129 1.00 29.30  ? 333  HIS A CE1   1 
ATOM   2651  N NE2   . HIS A 1 333 ? -59.908  -60.773  -23.596 1.00 35.30  ? 333  HIS A NE2   1 
ATOM   2652  N N     . ASP A 1 334 ? -58.295  -65.225  -18.983 1.00 29.95  ? 334  ASP A N     1 
ATOM   2653  C CA    . ASP A 1 334 ? -57.288  -65.614  -18.001 1.00 28.32  ? 334  ASP A CA    1 
ATOM   2654  C C     . ASP A 1 334 ? -55.920  -65.207  -18.529 1.00 24.06  ? 334  ASP A C     1 
ATOM   2655  O O     . ASP A 1 334 ? -55.748  -65.052  -19.747 1.00 22.48  ? 334  ASP A O     1 
ATOM   2656  C CB    . ASP A 1 334 ? -57.402  -67.075  -17.608 1.00 27.40  ? 334  ASP A CB    1 
ATOM   2657  C CG    . ASP A 1 334 ? -58.667  -67.402  -16.843 1.00 31.71  ? 334  ASP A CG    1 
ATOM   2658  O OD1   . ASP A 1 334 ? -59.043  -66.580  -15.975 1.00 38.31  ? 334  ASP A OD1   1 
ATOM   2659  O OD2   . ASP A 1 334 ? -59.252  -68.448  -17.115 1.00 32.78  ? 334  ASP A OD2   1 
ATOM   2660  N N     . PHE A 1 335 ? -54.983  -64.987  -17.596 1.00 21.09  ? 335  PHE A N     1 
ATOM   2661  C CA    . PHE A 1 335 ? -53.634  -64.587  -17.959 1.00 20.06  ? 335  PHE A CA    1 
ATOM   2662  C C     . PHE A 1 335 ? -52.655  -65.503  -17.232 1.00 21.08  ? 335  PHE A C     1 
ATOM   2663  O O     . PHE A 1 335 ? -52.778  -65.696  -16.021 1.00 22.72  ? 335  PHE A O     1 
ATOM   2664  C CB    . PHE A 1 335 ? -53.439  -63.118  -17.569 1.00 18.03  ? 335  PHE A CB    1 
ATOM   2665  C CG    . PHE A 1 335 ? -54.313  -62.121  -18.313 1.00 19.43  ? 335  PHE A CG    1 
ATOM   2666  C CD1   . PHE A 1 335 ? -55.617  -61.864  -17.902 1.00 21.69  ? 335  PHE A CD1   1 
ATOM   2667  C CD2   . PHE A 1 335 ? -53.839  -61.437  -19.432 1.00 19.88  ? 335  PHE A CD2   1 
ATOM   2668  C CE1   . PHE A 1 335 ? -56.405  -60.920  -18.576 1.00 22.22  ? 335  PHE A CE1   1 
ATOM   2669  C CE2   . PHE A 1 335 ? -54.641  -60.521  -20.115 1.00 19.91  ? 335  PHE A CE2   1 
ATOM   2670  C CZ    . PHE A 1 335 ? -55.917  -60.260  -19.692 1.00 19.01  ? 335  PHE A CZ    1 
ATOM   2671  N N     . LEU A 1 336 ? -51.720  -66.080  -17.993 1.00 20.91  ? 336  LEU A N     1 
ATOM   2672  C CA    . LEU A 1 336 ? -50.628  -66.867  -17.450 1.00 19.90  ? 336  LEU A CA    1 
ATOM   2673  C C     . LEU A 1 336 ? -49.469  -65.904  -17.192 1.00 25.23  ? 336  LEU A C     1 
ATOM   2674  O O     . LEU A 1 336 ? -49.018  -65.183  -18.106 1.00 26.17  ? 336  LEU A O     1 
ATOM   2675  C CB    . LEU A 1 336 ? -50.225  -67.945  -18.451 1.00 19.88  ? 336  LEU A CB    1 
ATOM   2676  C CG    . LEU A 1 336 ? -51.350  -68.820  -19.006 1.00 18.76  ? 336  LEU A CG    1 
ATOM   2677  C CD1   . LEU A 1 336 ? -50.793  -69.792  -20.047 1.00 15.12  ? 336  LEU A CD1   1 
ATOM   2678  C CD2   . LEU A 1 336 ? -52.005  -69.592  -17.856 1.00 19.66  ? 336  LEU A CD2   1 
ATOM   2679  N N     . CYS A 1 337 ? -49.028  -65.870  -15.926 1.00 21.58  ? 337  CYS A N     1 
ATOM   2680  C CA    . CYS A 1 337 ? -47.880  -65.077  -15.517 1.00 20.57  ? 337  CYS A CA    1 
ATOM   2681  C C     . CYS A 1 337 ? -46.706  -66.025  -15.357 1.00 18.23  ? 337  CYS A C     1 
ATOM   2682  O O     . CYS A 1 337 ? -46.724  -66.885  -14.491 1.00 20.60  ? 337  CYS A O     1 
ATOM   2683  C CB    . CYS A 1 337 ? -48.187  -64.311  -14.231 1.00 23.73  ? 337  CYS A CB    1 
ATOM   2684  S SG    . CYS A 1 337 ? -49.561  -63.152  -14.450 1.00 27.54  ? 337  CYS A SG    1 
ATOM   2685  N N     . ILE A 1 338 ? -45.713  -65.883  -16.225 1.00 19.73  ? 338  ILE A N     1 
ATOM   2686  C CA    . ILE A 1 338 ? -44.703  -66.915  -16.371 1.00 20.36  ? 338  ILE A CA    1 
ATOM   2687  C C     . ILE A 1 338 ? -43.332  -66.353  -16.006 1.00 20.17  ? 338  ILE A C     1 
ATOM   2688  O O     . ILE A 1 338 ? -42.944  -65.300  -16.509 1.00 19.00  ? 338  ILE A O     1 
ATOM   2689  C CB    . ILE A 1 338 ? -44.804  -67.518  -17.785 1.00 21.80  ? 338  ILE A CB    1 
ATOM   2690  C CG1   . ILE A 1 338 ? -46.143  -68.298  -17.867 1.00 23.79  ? 338  ILE A CG1   1 
ATOM   2691  C CG2   . ILE A 1 338 ? -43.620  -68.443  -18.035 1.00 19.66  ? 338  ILE A CG2   1 
ATOM   2692  C CD1   . ILE A 1 338 ? -46.437  -68.916  -19.208 1.00 27.55  ? 338  ILE A CD1   1 
ATOM   2693  N N     . LEU A 1 339 ? -42.648  -67.038  -15.078 1.00 18.97  ? 339  LEU A N     1 
ATOM   2694  C CA    . LEU A 1 339 ? -41.369  -66.603  -14.516 1.00 20.31  ? 339  LEU A CA    1 
ATOM   2695  C C     . LEU A 1 339 ? -40.228  -67.505  -14.996 1.00 20.97  ? 339  LEU A C     1 
ATOM   2696  O O     . LEU A 1 339 ? -40.474  -68.585  -15.560 1.00 20.65  ? 339  LEU A O     1 
ATOM   2697  C CB    . LEU A 1 339 ? -41.453  -66.580  -12.980 1.00 19.91  ? 339  LEU A CB    1 
ATOM   2698  C CG    . LEU A 1 339 ? -42.234  -65.393  -12.382 1.00 20.70  ? 339  LEU A CG    1 
ATOM   2699  C CD1   . LEU A 1 339 ? -43.756  -65.538  -12.540 1.00 19.72  ? 339  LEU A CD1   1 
ATOM   2700  C CD2   . LEU A 1 339 ? -41.891  -65.100  -10.927 1.00 19.36  ? 339  LEU A CD2   1 
ATOM   2701  N N     . ASP A 1 340 ? -38.975  -67.043  -14.782 1.00 20.66  ? 340  ASP A N     1 
ATOM   2702  C CA    . ASP A 1 340 ? -37.795  -67.865  -15.046 1.00 21.52  ? 340  ASP A CA    1 
ATOM   2703  C C     . ASP A 1 340 ? -37.673  -68.193  -16.534 1.00 20.96  ? 340  ASP A C     1 
ATOM   2704  O O     . ASP A 1 340 ? -37.299  -69.284  -16.868 1.00 22.53  ? 340  ASP A O     1 
ATOM   2705  C CB    . ASP A 1 340 ? -37.781  -69.124  -14.178 1.00 19.41  ? 340  ASP A CB    1 
ATOM   2706  C CG    . ASP A 1 340 ? -37.964  -68.801  -12.694 1.00 25.70  ? 340  ASP A CG    1 
ATOM   2707  O OD1   . ASP A 1 340 ? -37.129  -68.024  -12.153 1.00 28.16  ? 340  ASP A OD1   1 
ATOM   2708  O OD2   . ASP A 1 340 ? -38.964  -69.263  -12.064 1.00 26.57  ? 340  ASP A OD2   1 
ATOM   2709  N N     . LEU A 1 341 ? -37.988  -67.262  -17.425 1.00 21.94  ? 341  LEU A N     1 
ATOM   2710  C CA    . LEU A 1 341 ? -37.740  -67.443  -18.849 1.00 22.15  ? 341  LEU A CA    1 
ATOM   2711  C C     . LEU A 1 341 ? -36.363  -66.887  -19.189 1.00 23.16  ? 341  LEU A C     1 
ATOM   2712  O O     . LEU A 1 341 ? -35.879  -65.952  -18.542 1.00 24.47  ? 341  LEU A O     1 
ATOM   2713  C CB    . LEU A 1 341 ? -38.801  -66.727  -19.688 1.00 20.08  ? 341  LEU A CB    1 
ATOM   2714  C CG    . LEU A 1 341 ? -40.213  -67.308  -19.573 1.00 25.69  ? 341  LEU A CG    1 
ATOM   2715  C CD1   . LEU A 1 341 ? -41.151  -66.441  -20.377 1.00 21.76  ? 341  LEU A CD1   1 
ATOM   2716  C CD2   . LEU A 1 341 ? -40.245  -68.782  -20.038 1.00 22.62  ? 341  LEU A CD2   1 
ATOM   2717  N N     . GLN A 1 342 ? -35.786  -67.388  -20.278 1.00 23.55  ? 342  GLN A N     1 
ATOM   2718  C CA    . GLN A 1 342 ? -34.533  -66.842  -20.758 1.00 24.56  ? 342  GLN A CA    1 
ATOM   2719  C C     . GLN A 1 342 ? -34.674  -66.209  -22.135 1.00 25.31  ? 342  GLN A C     1 
ATOM   2720  O O     . GLN A 1 342 ? -35.706  -66.336  -22.781 1.00 26.11  ? 342  GLN A O     1 
ATOM   2721  C CB    . GLN A 1 342 ? -33.537  -67.988  -20.662 1.00 25.76  ? 342  GLN A CB    1 
ATOM   2722  C CG    . GLN A 1 342 ? -33.187  -68.266  -19.201 1.00 36.43  ? 342  GLN A CG    1 
ATOM   2723  C CD    . GLN A 1 342 ? -32.173  -69.375  -19.119 1.00 43.37  ? 342  GLN A CD    1 
ATOM   2724  O OE1   . GLN A 1 342 ? -32.501  -70.543  -19.319 1.00 46.78  ? 342  GLN A OE1   1 
ATOM   2725  N NE2   . GLN A 1 342 ? -30.921  -69.002  -18.915 1.00 52.90  ? 342  GLN A NE2   1 
ATOM   2726  N N     . VAL A 1 343 ? -33.625  -65.505  -22.563 1.00 25.02  ? 343  VAL A N     1 
ATOM   2727  C CA    . VAL A 1 343 ? -33.564  -64.877  -23.868 1.00 24.43  ? 343  VAL A CA    1 
ATOM   2728  C C     . VAL A 1 343 ? -33.198  -65.898  -24.948 1.00 26.90  ? 343  VAL A C     1 
ATOM   2729  O O     . VAL A 1 343 ? -32.469  -66.855  -24.701 1.00 28.60  ? 343  VAL A O     1 
ATOM   2730  C CB    . VAL A 1 343 ? -32.577  -63.702  -23.813 1.00 24.34  ? 343  VAL A CB    1 
ATOM   2731  C CG1   . VAL A 1 343 ? -32.462  -62.979  -25.155 1.00 21.12  ? 343  VAL A CG1   1 
ATOM   2732  C CG2   . VAL A 1 343 ? -32.879  -62.754  -22.659 1.00 19.60  ? 343  VAL A CG2   1 
ATOM   2733  N N     . VAL A 1 344 ? -33.783  -65.726  -26.143 1.00 27.47  ? 344  VAL A N     1 
ATOM   2734  C CA    . VAL A 1 344 ? -33.548  -66.605  -27.282 1.00 31.04  ? 344  VAL A CA    1 
ATOM   2735  C C     . VAL A 1 344 ? -32.443  -66.023  -28.165 1.00 32.93  ? 344  VAL A C     1 
ATOM   2736  O O     . VAL A 1 344 ? -32.610  -64.927  -28.687 1.00 35.69  ? 344  VAL A O     1 
ATOM   2737  C CB    . VAL A 1 344 ? -34.869  -66.730  -28.069 1.00 31.51  ? 344  VAL A CB    1 
ATOM   2738  C CG1   . VAL A 1 344 ? -34.699  -67.405  -29.426 1.00 35.56  ? 344  VAL A CG1   1 
ATOM   2739  C CG2   . VAL A 1 344 ? -35.942  -67.444  -27.258 1.00 28.65  ? 344  VAL A CG2   1 
ATOM   2740  N N     . GLY A 1 345 ? -31.358  -66.786  -28.382 1.00 37.90  ? 345  GLY A N     1 
ATOM   2741  C CA    . GLY A 1 345 ? -30.339  -66.522  -29.402 1.00 43.01  ? 345  GLY A CA    1 
ATOM   2742  C C     . GLY A 1 345 ? -30.723  -67.036  -30.806 1.00 54.70  ? 345  GLY A C     1 
ATOM   2743  O O     . GLY A 1 345 ? -31.874  -66.982  -31.236 1.00 59.20  ? 345  GLY A O     1 
ATOM   2744  N N     . LYS A 1 346 ? -29.738  -67.539  -31.556 1.00 65.61  ? 346  LYS A N     1 
ATOM   2745  C CA    . LYS A 1 346 ? -29.959  -67.997  -32.924 1.00 71.31  ? 346  LYS A CA    1 
ATOM   2746  C C     . LYS A 1 346 ? -28.756  -68.831  -33.349 1.00 76.69  ? 346  LYS A C     1 
ATOM   2747  O O     . LYS A 1 346 ? -27.621  -68.390  -33.134 1.00 77.20  ? 346  LYS A O     1 
ATOM   2748  C CB    . LYS A 1 346 ? -30.119  -66.858  -33.945 1.00 73.31  ? 346  LYS A CB    1 
ATOM   2749  C CG    . LYS A 1 346 ? -30.652  -67.356  -35.287 1.00 89.44  ? 346  LYS A CG    1 
ATOM   2750  C CD    . LYS A 1 346 ? -30.861  -66.392  -36.439 1.00 90.66  ? 346  LYS A CD    1 
ATOM   2751  C CE    . LYS A 1 346 ? -31.725  -67.045  -37.466 1.00 77.61  ? 346  LYS A CE    1 
ATOM   2752  N NZ    . LYS A 1 346 ? -31.620  -66.172  -38.626 1.00 79.10  ? 346  LYS A NZ    1 
ATOM   2753  N N     . ASP A 1 347 ? -29.027  -70.011  -33.944 1.00 75.64  ? 347  ASP A N     1 
ATOM   2754  C CA    . ASP A 1 347 ? -28.027  -70.922  -34.498 1.00 79.92  ? 347  ASP A CA    1 
ATOM   2755  C C     . ASP A 1 347 ? -26.993  -71.289  -33.431 1.00 74.32  ? 347  ASP A C     1 
ATOM   2756  O O     . ASP A 1 347 ? -27.321  -71.938  -32.451 1.00 61.42  ? 347  ASP A O     1 
ATOM   2757  C CB    . ASP A 1 347 ? -27.416  -70.424  -35.809 1.00 82.36  ? 347  ASP A CB    1 
ATOM   2758  C CG    . ASP A 1 347 ? -28.381  -70.063  -36.930 1.00 87.57  ? 347  ASP A CG    1 
ATOM   2759  O OD1   . ASP A 1 347 ? -29.324  -70.844  -37.179 1.00 91.70  ? 347  ASP A OD1   1 
ATOM   2760  O OD2   . ASP A 1 347 ? -28.183  -68.998  -37.549 1.00 78.29  ? 347  ASP A OD2   1 
ATOM   2761  N N     . ASN A 1 348 ? -25.746  -70.836  -33.628 1.00 81.05  ? 348  ASN A N     1 
ATOM   2762  C CA    . ASN A 1 348 ? -24.595  -71.137  -32.794 1.00 81.18  ? 348  ASN A CA    1 
ATOM   2763  C C     . ASN A 1 348 ? -24.670  -70.394  -31.451 1.00 83.31  ? 348  ASN A C     1 
ATOM   2764  O O     . ASN A 1 348 ? -24.014  -70.784  -30.482 1.00 65.29  ? 348  ASN A O     1 
ATOM   2765  C CB    . ASN A 1 348 ? -23.339  -70.656  -33.524 1.00 91.90  ? 348  ASN A CB    1 
ATOM   2766  C CG    . ASN A 1 348 ? -22.069  -71.378  -33.138 1.00 109.07 ? 348  ASN A CG    1 
ATOM   2767  O OD1   . ASN A 1 348 ? -22.004  -72.611  -33.229 1.00 103.58 ? 348  ASN A OD1   1 
ATOM   2768  N ND2   . ASN A 1 348 ? -21.050  -70.631  -32.727 1.00 106.44 ? 348  ASN A ND2   1 
ATOM   2769  N N     . VAL A 1 349 ? -25.431  -69.283  -31.418 1.00 77.87  ? 349  VAL A N     1 
ATOM   2770  C CA    . VAL A 1 349 ? -25.517  -68.409  -30.251 1.00 68.31  ? 349  VAL A CA    1 
ATOM   2771  C C     . VAL A 1 349 ? -26.680  -68.853  -29.362 1.00 57.80  ? 349  VAL A C     1 
ATOM   2772  O O     . VAL A 1 349 ? -27.840  -68.599  -29.670 1.00 55.11  ? 349  VAL A O     1 
ATOM   2773  C CB    . VAL A 1 349 ? -25.599  -66.912  -30.613 1.00 63.70  ? 349  VAL A CB    1 
ATOM   2774  C CG1   . VAL A 1 349 ? -25.354  -66.022  -29.391 1.00 56.57  ? 349  VAL A CG1   1 
ATOM   2775  C CG2   . VAL A 1 349 ? -24.641  -66.569  -31.751 1.00 62.94  ? 349  VAL A CG2   1 
ATOM   2776  N N     . VAL A 1 350 ? -26.339  -69.509  -28.249 1.00 54.10  ? 350  VAL A N     1 
ATOM   2777  C CA    . VAL A 1 350 ? -27.295  -70.124  -27.338 1.00 54.98  ? 350  VAL A CA    1 
ATOM   2778  C C     . VAL A 1 350 ? -27.361  -69.270  -26.069 1.00 54.49  ? 350  VAL A C     1 
ATOM   2779  O O     . VAL A 1 350 ? -26.355  -69.146  -25.365 1.00 57.71  ? 350  VAL A O     1 
ATOM   2780  C CB    . VAL A 1 350 ? -26.865  -71.585  -27.024 1.00 60.00  ? 350  VAL A CB    1 
ATOM   2781  C CG1   . VAL A 1 350 ? -27.716  -72.259  -25.929 1.00 47.17  ? 350  VAL A CG1   1 
ATOM   2782  C CG2   . VAL A 1 350 ? -26.749  -72.472  -28.272 1.00 49.28  ? 350  VAL A CG2   1 
ATOM   2783  N N     . LEU A 1 351 ? -28.537  -68.679  -25.791 1.00 49.13  ? 351  LEU A N     1 
ATOM   2784  C CA    . LEU A 1 351 ? -28.717  -67.804  -24.631 1.00 47.98  ? 351  LEU A CA    1 
ATOM   2785  C C     . LEU A 1 351 ? -29.556  -68.456  -23.517 1.00 49.04  ? 351  LEU A C     1 
ATOM   2786  O O     . LEU A 1 351 ? -29.602  -67.938  -22.391 1.00 48.34  ? 351  LEU A O     1 
ATOM   2787  C CB    . LEU A 1 351 ? -29.222  -66.411  -25.026 1.00 40.09  ? 351  LEU A CB    1 
ATOM   2788  C CG    . LEU A 1 351 ? -28.372  -65.672  -26.070 1.00 43.10  ? 351  LEU A CG    1 
ATOM   2789  C CD1   . LEU A 1 351 ? -29.131  -64.453  -26.555 1.00 36.87  ? 351  LEU A CD1   1 
ATOM   2790  C CD2   . LEU A 1 351 ? -26.975  -65.304  -25.536 1.00 36.55  ? 351  LEU A CD2   1 
ATOM   2791  N N     . GLY A 1 352 ? -30.138  -69.604  -23.817 1.00 42.17  ? 352  GLY A N     1 
ATOM   2792  C CA    . GLY A 1 352 ? -30.941  -70.379  -22.908 1.00 39.37  ? 352  GLY A CA    1 
ATOM   2793  C C     . GLY A 1 352 ? -32.426  -70.492  -23.112 1.00 44.79  ? 352  GLY A C     1 
ATOM   2794  O O     . GLY A 1 352 ? -33.005  -71.416  -22.628 1.00 43.03  ? 352  GLY A O     1 
ATOM   2795  N N     . GLY A 1 353 ? -33.032  -69.600  -23.863 1.00 43.35  ? 353  GLY A N     1 
ATOM   2796  C CA    . GLY A 1 353 ? -34.451  -69.669  -24.090 1.00 46.73  ? 353  GLY A CA    1 
ATOM   2797  C C     . GLY A 1 353 ? -34.912  -70.427  -25.312 1.00 44.65  ? 353  GLY A C     1 
ATOM   2798  O O     . GLY A 1 353 ? -36.065  -70.600  -25.486 1.00 46.27  ? 353  GLY A O     1 
ATOM   2799  N N     . GLU A 1 354 ? -34.003  -70.918  -26.125 1.00 44.16  ? 354  GLU A N     1 
ATOM   2800  C CA    . GLU A 1 354 ? -34.377  -71.567  -27.376 1.00 56.93  ? 354  GLU A CA    1 
ATOM   2801  C C     . GLU A 1 354 ? -35.194  -72.869  -27.479 1.00 53.17  ? 354  GLU A C     1 
ATOM   2802  O O     . GLU A 1 354 ? -35.966  -73.009  -28.397 1.00 56.96  ? 354  GLU A O     1 
ATOM   2803  C CB    . GLU A 1 354 ? -33.322  -71.399  -28.476 1.00 51.94  ? 354  GLU A CB    1 
ATOM   2804  C CG    . GLU A 1 354 ? -31.889  -71.638  -28.091 1.00 57.44  ? 354  GLU A CG    1 
ATOM   2805  C CD    . GLU A 1 354 ? -31.288  -70.602  -27.187 1.00 55.01  ? 354  GLU A CD    1 
ATOM   2806  O OE1   . GLU A 1 354 ? -31.017  -70.953  -26.070 1.00 51.40  ? 354  GLU A OE1   1 
ATOM   2807  O OE2   . GLU A 1 354 ? -31.066  -69.474  -27.570 1.00 44.65  ? 354  GLU A OE2   1 
ATOM   2808  N N     . GLY A 1 355 ? -35.036  -73.818  -26.581 1.00 42.06  ? 355  GLY A N     1 
ATOM   2809  C CA    . GLY A 1 355 ? -35.807  -75.039  -26.667 1.00 33.36  ? 355  GLY A CA    1 
ATOM   2810  C C     . GLY A 1 355 ? -37.271  -74.942  -26.307 1.00 33.95  ? 355  GLY A C     1 
ATOM   2811  O O     . GLY A 1 355 ? -37.707  -73.957  -25.786 1.00 35.41  ? 355  GLY A O     1 
ATOM   2812  N N     . VAL A 1 356 ? -38.038  -75.961  -26.638 1.00 24.61  ? 356  VAL A N     1 
ATOM   2813  C CA    . VAL A 1 356 ? -39.438  -76.041  -26.290 1.00 22.89  ? 356  VAL A CA    1 
ATOM   2814  C C     . VAL A 1 356 ? -39.500  -76.041  -24.764 1.00 23.13  ? 356  VAL A C     1 
ATOM   2815  O O     . VAL A 1 356 ? -38.795  -76.753  -24.134 1.00 23.93  ? 356  VAL A O     1 
ATOM   2816  C CB    . VAL A 1 356 ? -40.066  -77.288  -26.917 1.00 22.66  ? 356  VAL A CB    1 
ATOM   2817  C CG1   . VAL A 1 356 ? -41.443  -77.534  -26.407 1.00 20.38  ? 356  VAL A CG1   1 
ATOM   2818  C CG2   . VAL A 1 356 ? -40.131  -77.112  -28.399 1.00 24.51  ? 356  VAL A CG2   1 
ATOM   2819  N N     . ASN A 1 357 ? -40.425  -75.299  -24.205 1.00 21.38  ? 357  ASN A N     1 
ATOM   2820  C CA    . ASN A 1 357 ? -40.456  -75.041  -22.783 1.00 20.44  ? 357  ASN A CA    1 
ATOM   2821  C C     . ASN A 1 357 ? -41.876  -75.270  -22.267 1.00 20.32  ? 357  ASN A C     1 
ATOM   2822  O O     . ASN A 1 357 ? -42.641  -74.323  -22.062 1.00 21.89  ? 357  ASN A O     1 
ATOM   2823  C CB    . ASN A 1 357 ? -39.948  -73.619  -22.526 1.00 21.23  ? 357  ASN A CB    1 
ATOM   2824  C CG    . ASN A 1 357 ? -39.977  -73.195  -21.077 1.00 24.46  ? 357  ASN A CG    1 
ATOM   2825  O OD1   . ASN A 1 357 ? -40.027  -74.011  -20.145 1.00 26.28  ? 357  ASN A OD1   1 
ATOM   2826  N ND2   . ASN A 1 357 ? -39.992  -71.892  -20.859 1.00 24.38  ? 357  ASN A ND2   1 
ATOM   2827  N N     . PRO A 1 358 ? -42.307  -76.524  -22.056 1.00 20.18  ? 358  PRO A N     1 
ATOM   2828  C CA    . PRO A 1 358 ? -43.687  -76.787  -21.627 1.00 20.78  ? 358  PRO A CA    1 
ATOM   2829  C C     . PRO A 1 358 ? -43.975  -76.342  -20.193 1.00 21.42  ? 358  PRO A C     1 
ATOM   2830  O O     . PRO A 1 358 ? -43.343  -76.833  -19.266 1.00 26.98  ? 358  PRO A O     1 
ATOM   2831  C CB    . PRO A 1 358 ? -43.884  -78.297  -21.789 1.00 19.64  ? 358  PRO A CB    1 
ATOM   2832  C CG    . PRO A 1 358 ? -42.456  -78.825  -21.841 1.00 19.73  ? 358  PRO A CG    1 
ATOM   2833  C CD    . PRO A 1 358 ? -41.503  -77.731  -22.244 1.00 19.72  ? 358  PRO A CD    1 
ATOM   2834  N N     . ARG A 1 359 ? -44.913  -75.405  -20.021 1.00 19.72  ? 359  ARG A N     1 
ATOM   2835  C CA    . ARG A 1 359 ? -45.351  -74.959  -18.705 1.00 18.63  ? 359  ARG A CA    1 
ATOM   2836  C C     . ARG A 1 359 ? -46.822  -75.333  -18.560 1.00 20.05  ? 359  ARG A C     1 
ATOM   2837  O O     . ARG A 1 359 ? -47.638  -74.979  -19.405 1.00 23.34  ? 359  ARG A O     1 
ATOM   2838  C CB    . ARG A 1 359 ? -45.151  -73.446  -18.536 1.00 17.15  ? 359  ARG A CB    1 
ATOM   2839  C CG    . ARG A 1 359 ? -43.721  -72.951  -18.734 1.00 16.87  ? 359  ARG A CG    1 
ATOM   2840  C CD    . ARG A 1 359 ? -42.794  -73.517  -17.641 1.00 19.54  ? 359  ARG A CD    1 
ATOM   2841  N NE    . ARG A 1 359 ? -41.437  -72.956  -17.714 1.00 20.35  ? 359  ARG A NE    1 
ATOM   2842  C CZ    . ARG A 1 359 ? -41.049  -71.799  -17.163 1.00 19.98  ? 359  ARG A CZ    1 
ATOM   2843  N NH1   . ARG A 1 359 ? -41.881  -71.141  -16.363 1.00 18.21  ? 359  ARG A NH1   1 
ATOM   2844  N NH2   . ARG A 1 359 ? -39.819  -71.341  -17.410 1.00 17.93  ? 359  ARG A NH2   1 
ATOM   2845  N N     . SER A 1 360 ? -47.153  -76.015  -17.468 1.00 19.78  ? 360  SER A N     1 
ATOM   2846  C CA    . SER A 1 360 ? -48.476  -76.556  -17.244 1.00 20.38  ? 360  SER A CA    1 
ATOM   2847  C C     . SER A 1 360 ? -49.181  -75.894  -16.068 1.00 20.22  ? 360  SER A C     1 
ATOM   2848  O O     . SER A 1 360 ? -48.536  -75.370  -15.153 1.00 20.00  ? 360  SER A O     1 
ATOM   2849  C CB    . SER A 1 360 ? -48.438  -78.062  -17.065 1.00 20.64  ? 360  SER A CB    1 
ATOM   2850  O OG    . SER A 1 360 ? -47.959  -78.657  -18.264 1.00 22.26  ? 360  SER A OG    1 
ATOM   2851  N N     . PHE A 1 361 ? -50.524  -75.964  -16.134 1.00 18.67  ? 361  PHE A N     1 
ATOM   2852  C CA    . PHE A 1 361 ? -51.440  -75.389  -15.165 1.00 19.37  ? 361  PHE A CA    1 
ATOM   2853  C C     . PHE A 1 361 ? -52.584  -76.376  -15.007 1.00 21.37  ? 361  PHE A C     1 
ATOM   2854  O O     . PHE A 1 361 ? -52.933  -77.070  -15.967 1.00 22.21  ? 361  PHE A O     1 
ATOM   2855  C CB    . PHE A 1 361 ? -51.962  -74.073  -15.746 1.00 18.70  ? 361  PHE A CB    1 
ATOM   2856  C CG    . PHE A 1 361 ? -50.823  -73.105  -16.025 1.00 18.17  ? 361  PHE A CG    1 
ATOM   2857  C CD1   . PHE A 1 361 ? -50.376  -72.240  -15.021 1.00 21.08  ? 361  PHE A CD1   1 
ATOM   2858  C CD2   . PHE A 1 361 ? -50.147  -73.114  -17.245 1.00 18.10  ? 361  PHE A CD2   1 
ATOM   2859  C CE1   . PHE A 1 361 ? -49.322  -71.363  -15.259 1.00 20.98  ? 361  PHE A CE1   1 
ATOM   2860  C CE2   . PHE A 1 361 ? -49.064  -72.254  -17.482 1.00 18.47  ? 361  PHE A CE2   1 
ATOM   2861  C CZ    . PHE A 1 361 ? -48.662  -71.379  -16.495 1.00 18.68  ? 361  PHE A CZ    1 
ATOM   2862  N N     . VAL A 1 362 ? -53.130  -76.434  -13.791 1.00 20.17  ? 362  VAL A N     1 
ATOM   2863  C CA    . VAL A 1 362 ? -54.224  -77.314  -13.436 1.00 23.08  ? 362  VAL A CA    1 
ATOM   2864  C C     . VAL A 1 362 ? -55.375  -76.452  -12.933 1.00 25.91  ? 362  VAL A C     1 
ATOM   2865  O O     . VAL A 1 362 ? -55.196  -75.660  -11.997 1.00 27.26  ? 362  VAL A O     1 
ATOM   2866  C CB    . VAL A 1 362 ? -53.759  -78.235  -12.296 1.00 23.62  ? 362  VAL A CB    1 
ATOM   2867  C CG1   . VAL A 1 362 ? -54.921  -79.064  -11.732 1.00 21.98  ? 362  VAL A CG1   1 
ATOM   2868  C CG2   . VAL A 1 362 ? -52.600  -79.114  -12.767 1.00 22.09  ? 362  VAL A CG2   1 
ATOM   2869  N N     . GLY A 1 363 ? -56.547  -76.618  -13.552 1.00 25.78  ? 363  GLY A N     1 
ATOM   2870  C CA    . GLY A 1 363 ? -57.720  -75.880  -13.110 1.00 26.91  ? 363  GLY A CA    1 
ATOM   2871  C C     . GLY A 1 363 ? -58.402  -75.121  -14.247 1.00 28.02  ? 363  GLY A C     1 
ATOM   2872  O O     . GLY A 1 363 ? -59.401  -74.469  -14.022 1.00 33.59  ? 363  GLY A O     1 
ATOM   2873  N N     . ILE A 1 364 ? -57.909  -75.247  -15.477 1.00 30.91  ? 364  ILE A N     1 
ATOM   2874  C CA    . ILE A 1 364 ? -58.595  -74.632  -16.606 1.00 29.85  ? 364  ILE A CA    1 
ATOM   2875  C C     . ILE A 1 364 ? -59.397  -75.701  -17.339 1.00 32.50  ? 364  ILE A C     1 
ATOM   2876  O O     . ILE A 1 364 ? -58.832  -76.631  -17.911 1.00 33.58  ? 364  ILE A O     1 
ATOM   2877  C CB    . ILE A 1 364 ? -57.544  -73.947  -17.499 1.00 36.70  ? 364  ILE A CB    1 
ATOM   2878  C CG1   . ILE A 1 364 ? -57.025  -72.714  -16.775 1.00 33.75  ? 364  ILE A CG1   1 
ATOM   2879  C CG2   . ILE A 1 364 ? -58.129  -73.627  -18.878 1.00 31.01  ? 364  ILE A CG2   1 
ATOM   2880  C CD1   . ILE A 1 364 ? -55.933  -72.006  -17.502 1.00 34.56  ? 364  ILE A CD1   1 
ATOM   2881  N N     . GLY A 1 365 ? -60.725  -75.587  -17.280 1.00 37.63  ? 365  GLY A N     1 
ATOM   2882  C CA    . GLY A 1 365 ? -61.657  -76.595  -17.770 1.00 34.76  ? 365  GLY A CA    1 
ATOM   2883  C C     . GLY A 1 365 ? -62.354  -76.219  -19.089 1.00 36.79  ? 365  GLY A C     1 
ATOM   2884  O O     . GLY A 1 365 ? -63.073  -77.038  -19.645 1.00 38.74  ? 365  GLY A O     1 
ATOM   2885  N N     . GLN A 1 366 ? -62.121  -75.012  -19.626 1.00 34.14  ? 366  GLN A N     1 
ATOM   2886  C CA    . GLN A 1 366 ? -62.837  -74.525  -20.799 1.00 32.88  ? 366  GLN A CA    1 
ATOM   2887  C C     . GLN A 1 366 ? -61.936  -74.610  -22.019 1.00 31.85  ? 366  GLN A C     1 
ATOM   2888  O O     . GLN A 1 366 ? -60.746  -74.334  -21.923 1.00 29.82  ? 366  GLN A O     1 
ATOM   2889  C CB    . GLN A 1 366 ? -63.325  -73.083  -20.603 1.00 36.97  ? 366  GLN A CB    1 
ATOM   2890  C CG    . GLN A 1 366 ? -64.388  -72.926  -19.516 1.00 50.18  ? 366  GLN A CG    1 
ATOM   2891  C CD    . GLN A 1 366 ? -65.528  -73.922  -19.657 1.00 63.85  ? 366  GLN A CD    1 
ATOM   2892  O OE1   . GLN A 1 366 ? -66.173  -74.046  -20.711 1.00 63.09  ? 366  GLN A OE1   1 
ATOM   2893  N NE2   . GLN A 1 366 ? -65.774  -74.671  -18.589 1.00 70.16  ? 366  GLN A NE2   1 
ATOM   2894  N N     . PRO A 1 367 ? -62.464  -74.969  -23.215 1.00 34.68  ? 367  PRO A N     1 
ATOM   2895  C CA    . PRO A 1 367 ? -61.610  -75.012  -24.409 1.00 31.00  ? 367  PRO A CA    1 
ATOM   2896  C C     . PRO A 1 367 ? -61.073  -73.645  -24.789 1.00 28.82  ? 367  PRO A C     1 
ATOM   2897  O O     . PRO A 1 367 ? -61.802  -72.664  -24.700 1.00 28.07  ? 367  PRO A O     1 
ATOM   2898  C CB    . PRO A 1 367 ? -62.502  -75.591  -25.520 1.00 29.76  ? 367  PRO A CB    1 
ATOM   2899  C CG    . PRO A 1 367 ? -63.903  -75.654  -24.917 1.00 30.62  ? 367  PRO A CG    1 
ATOM   2900  C CD    . PRO A 1 367 ? -63.865  -75.385  -23.443 1.00 29.86  ? 367  PRO A CD    1 
ATOM   2901  N N     . ILE A 1 368 ? -59.825  -73.609  -25.278 1.00 26.70  ? 368  ILE A N     1 
ATOM   2902  C CA    . ILE A 1 368 ? -59.161  -72.344  -25.522 1.00 30.43  ? 368  ILE A CA    1 
ATOM   2903  C C     . ILE A 1 368 ? -59.088  -72.142  -27.029 1.00 31.76  ? 368  ILE A C     1 
ATOM   2904  O O     . ILE A 1 368 ? -58.793  -73.077  -27.759 1.00 32.05  ? 368  ILE A O     1 
ATOM   2905  C CB    . ILE A 1 368 ? -57.773  -72.305  -24.839 1.00 26.07  ? 368  ILE A CB    1 
ATOM   2906  C CG1   . ILE A 1 368 ? -57.909  -72.090  -23.324 1.00 27.07  ? 368  ILE A CG1   1 
ATOM   2907  C CG2   . ILE A 1 368 ? -56.860  -71.249  -25.473 1.00 21.95  ? 368  ILE A CG2   1 
ATOM   2908  C CD1   . ILE A 1 368 ? -56.677  -72.448  -22.509 1.00 25.19  ? 368  ILE A CD1   1 
ATOM   2909  N N     . GLN A 1 369 ? -59.280  -70.898  -27.475 1.00 30.50  ? 369  GLN A N     1 
ATOM   2910  C CA    . GLN A 1 369 ? -59.099  -70.607  -28.880 1.00 32.73  ? 369  GLN A CA    1 
ATOM   2911  C C     . GLN A 1 369 ? -57.658  -70.180  -29.180 1.00 32.14  ? 369  GLN A C     1 
ATOM   2912  O O     . GLN A 1 369 ? -57.077  -70.634  -30.165 1.00 30.89  ? 369  GLN A O     1 
ATOM   2913  C CB    . GLN A 1 369 ? -60.101  -69.555  -29.315 1.00 35.26  ? 369  GLN A CB    1 
ATOM   2914  C CG    . GLN A 1 369 ? -60.107  -69.347  -30.823 1.00 53.55  ? 369  GLN A CG    1 
ATOM   2915  C CD    . GLN A 1 369 ? -61.104  -68.286  -31.209 1.00 76.78  ? 369  GLN A CD    1 
ATOM   2916  O OE1   . GLN A 1 369 ? -61.159  -67.178  -30.653 1.00 76.40  ? 369  GLN A OE1   1 
ATOM   2917  N NE2   . GLN A 1 369 ? -61.948  -68.652  -32.157 1.00 77.21  ? 369  GLN A NE2   1 
ATOM   2918  N N     . ARG A 1 370 ? -57.099  -69.262  -28.376 1.00 27.49  ? 370  ARG A N     1 
ATOM   2919  C CA    . ARG A 1 370 ? -55.797  -68.706  -28.709 1.00 29.82  ? 370  ARG A CA    1 
ATOM   2920  C C     . ARG A 1 370 ? -55.108  -68.230  -27.421 1.00 29.83  ? 370  ARG A C     1 
ATOM   2921  O O     . ARG A 1 370 ? -55.771  -67.776  -26.469 1.00 26.18  ? 370  ARG A O     1 
ATOM   2922  C CB    . ARG A 1 370 ? -56.090  -67.518  -29.628 1.00 31.09  ? 370  ARG A CB    1 
ATOM   2923  C CG    . ARG A 1 370 ? -55.008  -67.122  -30.615 1.00 49.18  ? 370  ARG A CG    1 
ATOM   2924  C CD    . ARG A 1 370 ? -55.501  -65.919  -31.400 1.00 76.03  ? 370  ARG A CD    1 
ATOM   2925  N NE    . ARG A 1 370 ? -55.770  -66.425  -32.752 1.00 110.33 ? 370  ARG A NE    1 
ATOM   2926  C CZ    . ARG A 1 370 ? -56.940  -66.493  -33.389 1.00 108.91 ? 370  ARG A CZ    1 
ATOM   2927  N NH1   . ARG A 1 370 ? -58.076  -66.253  -32.749 1.00 99.45  ? 370  ARG A NH1   1 
ATOM   2928  N NH2   . ARG A 1 370 ? -56.966  -66.821  -34.673 1.00 98.28  ? 370  ARG A NH2   1 
ATOM   2929  N N     . ILE A 1 371 ? -53.768  -68.309  -27.411 1.00 25.03  ? 371  ILE A N     1 
ATOM   2930  C CA    . ILE A 1 371 ? -52.968  -67.762  -26.320 1.00 23.35  ? 371  ILE A CA    1 
ATOM   2931  C C     . ILE A 1 371 ? -51.856  -66.925  -26.941 1.00 22.93  ? 371  ILE A C     1 
ATOM   2932  O O     . ILE A 1 371 ? -51.191  -67.396  -27.867 1.00 27.03  ? 371  ILE A O     1 
ATOM   2933  C CB    . ILE A 1 371 ? -52.384  -68.899  -25.457 1.00 21.17  ? 371  ILE A CB    1 
ATOM   2934  C CG1   . ILE A 1 371 ? -53.460  -69.894  -25.020 1.00 19.03  ? 371  ILE A CG1   1 
ATOM   2935  C CG2   . ILE A 1 371 ? -51.594  -68.326  -24.275 1.00 19.77  ? 371  ILE A CG2   1 
ATOM   2936  C CD1   . ILE A 1 371 ? -52.958  -71.016  -24.122 1.00 21.38  ? 371  ILE A CD1   1 
ATOM   2937  N N     . HIS A 1 372 ? -51.600  -65.725  -26.394 1.00 19.74  ? 372  HIS A N     1 
ATOM   2938  C CA    . HIS A 1 372 ? -50.544  -64.887  -26.963 1.00 22.08  ? 372  HIS A CA    1 
ATOM   2939  C C     . HIS A 1 372 ? -49.841  -64.062  -25.877 1.00 20.31  ? 372  HIS A C     1 
ATOM   2940  O O     . HIS A 1 372 ? -50.474  -63.648  -24.903 1.00 20.98  ? 372  HIS A O     1 
ATOM   2941  C CB    . HIS A 1 372 ? -51.089  -64.021  -28.112 1.00 24.09  ? 372  HIS A CB    1 
ATOM   2942  C CG    . HIS A 1 372 ? -52.058  -62.980  -27.661 1.00 36.28  ? 372  HIS A CG    1 
ATOM   2943  N ND1   . HIS A 1 372 ? -53.421  -63.206  -27.550 1.00 41.23  ? 372  HIS A ND1   1 
ATOM   2944  C CD2   . HIS A 1 372 ? -51.854  -61.685  -27.248 1.00 45.91  ? 372  HIS A CD2   1 
ATOM   2945  C CE1   . HIS A 1 372 ? -54.007  -62.089  -27.122 1.00 40.95  ? 372  HIS A CE1   1 
ATOM   2946  N NE2   . HIS A 1 372 ? -53.077  -61.155  -26.940 1.00 46.02  ? 372  HIS A NE2   1 
ATOM   2947  N N     . TRP A 1 373 ? -48.537  -63.829  -26.062 1.00 17.22  ? 373  TRP A N     1 
ATOM   2948  C CA    . TRP A 1 373 ? -47.769  -62.969  -25.165 1.00 19.98  ? 373  TRP A CA    1 
ATOM   2949  C C     . TRP A 1 373 ? -48.256  -61.522  -25.302 1.00 20.97  ? 373  TRP A C     1 
ATOM   2950  O O     . TRP A 1 373 ? -48.386  -61.020  -26.424 1.00 22.35  ? 373  TRP A O     1 
ATOM   2951  C CB    . TRP A 1 373 ? -46.281  -63.034  -25.541 1.00 17.42  ? 373  TRP A CB    1 
ATOM   2952  C CG    . TRP A 1 373 ? -45.557  -64.312  -25.207 1.00 18.65  ? 373  TRP A CG    1 
ATOM   2953  C CD1   . TRP A 1 373 ? -44.755  -65.015  -26.068 1.00 18.49  ? 373  TRP A CD1   1 
ATOM   2954  C CD2   . TRP A 1 373 ? -45.463  -64.989  -23.926 1.00 17.37  ? 373  TRP A CD2   1 
ATOM   2955  N NE1   . TRP A 1 373 ? -44.204  -66.100  -25.431 1.00 18.69  ? 373  TRP A NE1   1 
ATOM   2956  C CE2   . TRP A 1 373 ? -44.603  -66.106  -24.111 1.00 17.84  ? 373  TRP A CE2   1 
ATOM   2957  C CE3   . TRP A 1 373 ? -46.013  -64.773  -22.653 1.00 17.04  ? 373  TRP A CE3   1 
ATOM   2958  C CZ2   . TRP A 1 373 ? -44.272  -66.990  -23.076 1.00 17.55  ? 373  TRP A CZ2   1 
ATOM   2959  C CZ3   . TRP A 1 373 ? -45.684  -65.635  -21.622 1.00 19.63  ? 373  TRP A CZ3   1 
ATOM   2960  C CH2   . TRP A 1 373 ? -44.822  -66.740  -21.834 1.00 20.41  ? 373  TRP A CH2   1 
ATOM   2961  N N     . LEU A 1 374 ? -48.471  -60.833  -24.171 1.00 21.22  ? 374  LEU A N     1 
ATOM   2962  C CA    . LEU A 1 374 ? -48.821  -59.415  -24.159 1.00 20.32  ? 374  LEU A CA    1 
ATOM   2963  C C     . LEU A 1 374 ? -47.724  -58.555  -24.762 1.00 20.90  ? 374  LEU A C     1 
ATOM   2964  O O     . LEU A 1 374 ? -48.039  -57.548  -25.352 1.00 22.51  ? 374  LEU A O     1 
ATOM   2965  C CB    . LEU A 1 374 ? -49.146  -58.884  -22.765 1.00 18.30  ? 374  LEU A CB    1 
ATOM   2966  C CG    . LEU A 1 374 ? -50.461  -59.417  -22.185 1.00 18.35  ? 374  LEU A CG    1 
ATOM   2967  C CD1   . LEU A 1 374 ? -50.759  -58.691  -20.883 1.00 15.61  ? 374  LEU A CD1   1 
ATOM   2968  C CD2   . LEU A 1 374 ? -51.629  -59.298  -23.187 1.00 14.62  ? 374  LEU A CD2   1 
ATOM   2969  N N     . ASP A 1 375 ? -46.446  -58.902  -24.582 1.00 24.16  ? 375  ASP A N     1 
ATOM   2970  C CA    . ASP A 1 375 ? -45.392  -57.981  -24.977 1.00 23.92  ? 375  ASP A CA    1 
ATOM   2971  C C     . ASP A 1 375 ? -45.247  -57.880  -26.498 1.00 24.65  ? 375  ASP A C     1 
ATOM   2972  O O     . ASP A 1 375 ? -44.806  -56.844  -26.981 1.00 24.47  ? 375  ASP A O     1 
ATOM   2973  C CB    . ASP A 1 375 ? -44.054  -58.344  -24.358 1.00 25.52  ? 375  ASP A CB    1 
ATOM   2974  C CG    . ASP A 1 375 ? -43.648  -59.786  -24.596 1.00 26.83  ? 375  ASP A CG    1 
ATOM   2975  O OD1   . ASP A 1 375 ? -44.227  -60.666  -23.908 1.00 24.29  ? 375  ASP A OD1   1 
ATOM   2976  O OD2   . ASP A 1 375 ? -42.819  -60.026  -25.518 1.00 29.67  ? 375  ASP A OD2   1 
ATOM   2977  N N     . ASN A 1 376 ? -45.539  -58.944  -27.268 1.00 22.56  ? 376  ASN A N     1 
ATOM   2978  C CA    . ASN A 1 376 ? -45.247  -58.882  -28.695 1.00 19.78  ? 376  ASN A CA    1 
ATOM   2979  C C     . ASN A 1 376 ? -46.316  -59.610  -29.515 1.00 23.17  ? 376  ASN A C     1 
ATOM   2980  O O     . ASN A 1 376 ? -46.142  -59.787  -30.715 1.00 28.03  ? 376  ASN A O     1 
ATOM   2981  C CB    . ASN A 1 376 ? -43.859  -59.425  -29.027 1.00 19.22  ? 376  ASN A CB    1 
ATOM   2982  C CG    . ASN A 1 376 ? -43.759  -60.931  -28.820 1.00 22.07  ? 376  ASN A CG    1 
ATOM   2983  O OD1   . ASN A 1 376 ? -44.690  -61.572  -28.279 1.00 20.01  ? 376  ASN A OD1   1 
ATOM   2984  N ND2   . ASN A 1 376 ? -42.622  -61.505  -29.196 1.00 18.71  ? 376  ASN A ND2   1 
ATOM   2985  N N     . ASP A 1 377 ? -47.386  -60.100  -28.892 1.00 25.56  ? 377  ASP A N     1 
ATOM   2986  C CA    . ASP A 1 377 ? -48.474  -60.769  -29.604 1.00 33.70  ? 377  ASP A CA    1 
ATOM   2987  C C     . ASP A 1 377 ? -48.101  -62.112  -30.243 1.00 28.81  ? 377  ASP A C     1 
ATOM   2988  O O     . ASP A 1 377 ? -48.874  -62.629  -31.044 1.00 26.64  ? 377  ASP A O     1 
ATOM   2989  C CB    . ASP A 1 377 ? -49.176  -59.873  -30.615 1.00 40.06  ? 377  ASP A CB    1 
ATOM   2990  C CG    . ASP A 1 377 ? -49.936  -58.709  -30.008 1.00 58.30  ? 377  ASP A CG    1 
ATOM   2991  O OD1   . ASP A 1 377 ? -50.663  -58.925  -29.003 1.00 77.05  ? 377  ASP A OD1   1 
ATOM   2992  O OD2   . ASP A 1 377 ? -49.786  -57.599  -30.547 1.00 80.29  ? 377  ASP A OD2   1 
ATOM   2993  N N     . GLU A 1 378 ? -46.950  -62.701  -29.910 1.00 25.46  ? 378  GLU A N     1 
ATOM   2994  C CA    . GLU A 1 378 ? -46.652  -64.014  -30.461 1.00 24.58  ? 378  GLU A CA    1 
ATOM   2995  C C     . GLU A 1 378 ? -47.705  -65.019  -29.959 1.00 26.10  ? 378  GLU A C     1 
ATOM   2996  O O     . GLU A 1 378 ? -48.050  -65.015  -28.772 1.00 26.45  ? 378  GLU A O     1 
ATOM   2997  C CB    . GLU A 1 378 ? -45.219  -64.402  -30.105 1.00 23.85  ? 378  GLU A CB    1 
ATOM   2998  C CG    . GLU A 1 378 ? -44.859  -65.799  -30.621 1.00 26.69  ? 378  GLU A CG    1 
ATOM   2999  C CD    . GLU A 1 378 ? -43.633  -66.402  -29.936 1.00 30.89  ? 378  GLU A CD    1 
ATOM   3000  O OE1   . GLU A 1 378 ? -43.080  -65.794  -29.013 1.00 29.54  ? 378  GLU A OE1   1 
ATOM   3001  O OE2   . GLU A 1 378 ? -43.145  -67.454  -30.380 1.00 37.68  ? 378  GLU A OE2   1 
ATOM   3002  N N     . VAL A 1 379 ? -48.204  -65.868  -30.869 1.00 25.58  ? 379  VAL A N     1 
ATOM   3003  C CA    . VAL A 1 379 ? -49.180  -66.898  -30.541 1.00 25.71  ? 379  VAL A CA    1 
ATOM   3004  C C     . VAL A 1 379 ? -48.445  -68.122  -30.005 1.00 26.41  ? 379  VAL A C     1 
ATOM   3005  O O     . VAL A 1 379 ? -47.454  -68.530  -30.595 1.00 27.72  ? 379  VAL A O     1 
ATOM   3006  C CB    . VAL A 1 379 ? -49.955  -67.256  -31.830 1.00 30.52  ? 379  VAL A CB    1 
ATOM   3007  C CG1   . VAL A 1 379 ? -50.806  -68.529  -31.666 1.00 28.46  ? 379  VAL A CG1   1 
ATOM   3008  C CG2   . VAL A 1 379 ? -50.825  -66.086  -32.291 1.00 23.63  ? 379  VAL A CG2   1 
ATOM   3009  N N     . LEU A 1 380 ? -48.931  -68.693  -28.893 1.00 24.29  ? 380  LEU A N     1 
ATOM   3010  C CA    . LEU A 1 380 ? -48.273  -69.820  -28.253 1.00 26.54  ? 380  LEU A CA    1 
ATOM   3011  C C     . LEU A 1 380 ? -48.978  -71.113  -28.661 1.00 26.96  ? 380  LEU A C     1 
ATOM   3012  O O     . LEU A 1 380 ? -50.202  -71.168  -28.741 1.00 25.22  ? 380  LEU A O     1 
ATOM   3013  C CB    . LEU A 1 380 ? -48.310  -69.670  -26.727 1.00 23.53  ? 380  LEU A CB    1 
ATOM   3014  C CG    . LEU A 1 380 ? -47.712  -68.379  -26.150 1.00 27.14  ? 380  LEU A CG    1 
ATOM   3015  C CD1   . LEU A 1 380 ? -47.459  -68.582  -24.668 1.00 25.78  ? 380  LEU A CD1   1 
ATOM   3016  C CD2   . LEU A 1 380 ? -46.398  -68.134  -26.879 1.00 26.86  ? 380  LEU A CD2   1 
ATOM   3017  N N     . SER A 1 381 ? -48.211  -72.185  -28.834 1.00 22.66  ? 381  SER A N     1 
ATOM   3018  C CA    . SER A 1 381 ? -48.882  -73.457  -29.015 1.00 26.00  ? 381  SER A CA    1 
ATOM   3019  C C     . SER A 1 381 ? -49.237  -74.064  -27.650 1.00 30.55  ? 381  SER A C     1 
ATOM   3020  O O     . SER A 1 381 ? -48.570  -73.761  -26.650 1.00 27.04  ? 381  SER A O     1 
ATOM   3021  C CB    . SER A 1 381 ? -48.070  -74.357  -29.884 1.00 23.87  ? 381  SER A CB    1 
ATOM   3022  O OG    . SER A 1 381 ? -46.791  -74.532  -29.336 1.00 30.00  ? 381  SER A OG    1 
ATOM   3023  N N     . PHE A 1 382 ? -50.302  -74.887  -27.600 1.00 23.91  ? 382  PHE A N     1 
ATOM   3024  C CA    . PHE A 1 382 ? -50.779  -75.404  -26.329 1.00 22.87  ? 382  PHE A CA    1 
ATOM   3025  C C     . PHE A 1 382 ? -51.538  -76.716  -26.558 1.00 25.32  ? 382  PHE A C     1 
ATOM   3026  O O     . PHE A 1 382 ? -51.948  -77.000  -27.668 1.00 26.35  ? 382  PHE A O     1 
ATOM   3027  C CB    . PHE A 1 382 ? -51.667  -74.349  -25.656 1.00 23.21  ? 382  PHE A CB    1 
ATOM   3028  C CG    . PHE A 1 382 ? -52.992  -74.099  -26.375 1.00 20.99  ? 382  PHE A CG    1 
ATOM   3029  C CD1   . PHE A 1 382 ? -54.121  -74.873  -26.075 1.00 23.61  ? 382  PHE A CD1   1 
ATOM   3030  C CD2   . PHE A 1 382 ? -53.100  -73.131  -27.363 1.00 19.72  ? 382  PHE A CD2   1 
ATOM   3031  C CE1   . PHE A 1 382 ? -55.330  -74.699  -26.751 1.00 21.92  ? 382  PHE A CE1   1 
ATOM   3032  C CE2   . PHE A 1 382 ? -54.310  -72.921  -28.016 1.00 21.24  ? 382  PHE A CE2   1 
ATOM   3033  C CZ    . PHE A 1 382 ? -55.427  -73.715  -27.712 1.00 21.08  ? 382  PHE A CZ    1 
ATOM   3034  N N     . THR A 1 383 ? -51.706  -77.520  -25.500 1.00 25.04  ? 383  THR A N     1 
ATOM   3035  C CA    . THR A 1 383 ? -52.558  -78.701  -25.489 1.00 27.52  ? 383  THR A CA    1 
ATOM   3036  C C     . THR A 1 383 ? -53.416  -78.613  -24.229 1.00 25.44  ? 383  THR A C     1 
ATOM   3037  O O     . THR A 1 383 ? -52.994  -78.013  -23.233 1.00 25.43  ? 383  THR A O     1 
ATOM   3038  C CB    . THR A 1 383 ? -51.744  -80.005  -25.490 1.00 26.66  ? 383  THR A CB    1 
ATOM   3039  O OG1   . THR A 1 383 ? -50.972  -79.994  -24.289 1.00 32.69  ? 383  THR A OG1   1 
ATOM   3040  C CG2   . THR A 1 383 ? -50.765  -80.138  -26.649 1.00 19.26  ? 383  THR A CG2   1 
ATOM   3041  N N     . GLN A 1 384 ? -54.602  -79.227  -24.276 1.00 23.91  ? 384  GLN A N     1 
ATOM   3042  C CA    . GLN A 1 384 ? -55.452  -79.295  -23.100 1.00 26.81  ? 384  GLN A CA    1 
ATOM   3043  C C     . GLN A 1 384 ? -55.894  -80.725  -22.854 1.00 29.11  ? 384  GLN A C     1 
ATOM   3044  O O     . GLN A 1 384 ? -56.026  -81.496  -23.789 1.00 29.59  ? 384  GLN A O     1 
ATOM   3045  C CB    . GLN A 1 384 ? -56.731  -78.477  -23.281 1.00 24.97  ? 384  GLN A CB    1 
ATOM   3046  C CG    . GLN A 1 384 ? -56.441  -76.991  -23.459 1.00 25.72  ? 384  GLN A CG    1 
ATOM   3047  C CD    . GLN A 1 384 ? -57.697  -76.154  -23.471 1.00 22.70  ? 384  GLN A CD    1 
ATOM   3048  O OE1   . GLN A 1 384 ? -58.223  -75.816  -24.536 1.00 26.87  ? 384  GLN A OE1   1 
ATOM   3049  N NE2   . GLN A 1 384 ? -58.174  -75.784  -22.298 1.00 19.12  ? 384  GLN A NE2   1 
ATOM   3050  N N     . ASP A 1 385 ? -56.100  -81.061  -21.582 1.00 29.79  ? 385  ASP A N     1 
ATOM   3051  C CA    . ASP A 1 385 ? -56.914  -82.195  -21.178 1.00 28.83  ? 385  ASP A CA    1 
ATOM   3052  C C     . ASP A 1 385 ? -58.073  -81.627  -20.357 1.00 32.27  ? 385  ASP A C     1 
ATOM   3053  O O     . ASP A 1 385 ? -57.889  -81.278  -19.175 1.00 28.41  ? 385  ASP A O     1 
ATOM   3054  C CB    . ASP A 1 385 ? -56.097  -83.212  -20.388 1.00 27.79  ? 385  ASP A CB    1 
ATOM   3055  C CG    . ASP A 1 385 ? -56.893  -84.361  -19.770 1.00 35.43  ? 385  ASP A CG    1 
ATOM   3056  O OD1   . ASP A 1 385 ? -58.164  -84.255  -19.684 1.00 35.25  ? 385  ASP A OD1   1 
ATOM   3057  O OD2   . ASP A 1 385 ? -56.251  -85.367  -19.388 1.00 44.60  ? 385  ASP A OD2   1 
ATOM   3058  N N     . LEU A 1 386 ? -59.253  -81.532  -20.992 1.00 29.58  ? 386  LEU A N     1 
ATOM   3059  C CA    . LEU A 1 386 ? -60.382  -80.854  -20.376 1.00 31.25  ? 386  LEU A CA    1 
ATOM   3060  C C     . LEU A 1 386 ? -60.907  -81.626  -19.164 1.00 31.24  ? 386  LEU A C     1 
ATOM   3061  O O     . LEU A 1 386 ? -61.341  -81.021  -18.198 1.00 31.58  ? 386  LEU A O     1 
ATOM   3062  C CB    . LEU A 1 386 ? -61.481  -80.511  -21.377 1.00 29.40  ? 386  LEU A CB    1 
ATOM   3063  C CG    . LEU A 1 386 ? -61.021  -79.633  -22.545 1.00 31.06  ? 386  LEU A CG    1 
ATOM   3064  C CD1   . LEU A 1 386 ? -62.049  -79.582  -23.668 1.00 35.42  ? 386  LEU A CD1   1 
ATOM   3065  C CD2   . LEU A 1 386 ? -60.713  -78.222  -22.036 1.00 27.24  ? 386  LEU A CD2   1 
ATOM   3066  N N     . ASP A 1 387 ? -60.826  -82.957  -19.175 1.00 34.85  ? 387  ASP A N     1 
ATOM   3067  C CA    . ASP A 1 387 ? -61.347  -83.714  -18.037 1.00 38.54  ? 387  ASP A CA    1 
ATOM   3068  C C     . ASP A 1 387 ? -60.518  -83.472  -16.783 1.00 36.12  ? 387  ASP A C     1 
ATOM   3069  O O     . ASP A 1 387 ? -61.076  -83.357  -15.703 1.00 38.52  ? 387  ASP A O     1 
ATOM   3070  C CB    . ASP A 1 387 ? -61.502  -85.200  -18.323 1.00 54.72  ? 387  ASP A CB    1 
ATOM   3071  C CG    . ASP A 1 387 ? -62.384  -85.487  -19.533 1.00 73.58  ? 387  ASP A CG    1 
ATOM   3072  O OD1   . ASP A 1 387 ? -63.521  -84.928  -19.615 1.00 69.31  ? 387  ASP A OD1   1 
ATOM   3073  O OD2   . ASP A 1 387 ? -61.891  -86.200  -20.424 1.00 82.98  ? 387  ASP A OD2   1 
ATOM   3074  N N     . LYS A 1 388 ? -59.190  -83.390  -16.924 1.00 34.27  ? 388  LYS A N     1 
ATOM   3075  C CA    . LYS A 1 388 ? -58.328  -83.232  -15.765 1.00 31.14  ? 388  LYS A CA    1 
ATOM   3076  C C     . LYS A 1 388 ? -58.012  -81.754  -15.543 1.00 29.39  ? 388  LYS A C     1 
ATOM   3077  O O     . LYS A 1 388 ? -57.411  -81.406  -14.533 1.00 28.44  ? 388  LYS A O     1 
ATOM   3078  C CB    . LYS A 1 388 ? -57.144  -84.199  -15.871 1.00 32.06  ? 388  LYS A CB    1 
ATOM   3079  C CG    . LYS A 1 388 ? -57.567  -85.558  -15.360 1.00 28.39  ? 388  LYS A CG    1 
ATOM   3080  C CD    . LYS A 1 388 ? -56.464  -86.579  -15.464 1.00 28.45  ? 388  LYS A CD    1 
ATOM   3081  C CE    . LYS A 1 388 ? -56.774  -87.841  -14.716 1.00 32.80  ? 388  LYS A CE    1 
ATOM   3082  N NZ    . LYS A 1 388 ? -55.540  -88.637  -14.819 1.00 30.03  ? 388  LYS A NZ    1 
ATOM   3083  N N     . LYS A 1 389 ? -58.447  -80.909  -16.483 1.00 25.19  ? 389  LYS A N     1 
ATOM   3084  C CA    . LYS A 1 389 ? -58.305  -79.465  -16.382 1.00 29.47  ? 389  LYS A CA    1 
ATOM   3085  C C     . LYS A 1 389 ? -56.833  -79.069  -16.468 1.00 28.13  ? 389  LYS A C     1 
ATOM   3086  O O     . LYS A 1 389 ? -56.374  -78.186  -15.734 1.00 28.13  ? 389  LYS A O     1 
ATOM   3087  C CB    . LYS A 1 389 ? -59.037  -78.882  -15.173 1.00 35.26  ? 389  LYS A CB    1 
ATOM   3088  C CG    . LYS A 1 389 ? -60.529  -79.244  -15.015 1.00 42.29  ? 389  LYS A CG    1 
ATOM   3089  C CD    . LYS A 1 389 ? -61.072  -78.300  -13.939 1.00 53.54  ? 389  LYS A CD    1 
ATOM   3090  C CE    . LYS A 1 389 ? -62.142  -78.745  -12.968 1.00 64.49  ? 389  LYS A CE    1 
ATOM   3091  N NZ    . LYS A 1 389 ? -63.362  -78.497  -13.716 1.00 65.02  ? 389  LYS A NZ    1 
ATOM   3092  N N     . VAL A 1 390 ? -56.118  -79.693  -17.417 1.00 21.10  ? 390  VAL A N     1 
ATOM   3093  C CA    . VAL A 1 390 ? -54.714  -79.425  -17.631 1.00 20.88  ? 390  VAL A CA    1 
ATOM   3094  C C     . VAL A 1 390 ? -54.541  -78.574  -18.883 1.00 22.89  ? 390  VAL A C     1 
ATOM   3095  O O     . VAL A 1 390 ? -55.099  -78.897  -19.926 1.00 23.43  ? 390  VAL A O     1 
ATOM   3096  C CB    . VAL A 1 390 ? -53.867  -80.708  -17.716 1.00 20.38  ? 390  VAL A CB    1 
ATOM   3097  C CG1   . VAL A 1 390 ? -52.400  -80.384  -17.997 1.00 17.18  ? 390  VAL A CG1   1 
ATOM   3098  C CG2   . VAL A 1 390 ? -54.008  -81.566  -16.444 1.00 18.29  ? 390  VAL A CG2   1 
ATOM   3099  N N     . LEU A 1 391 ? -53.745  -77.504  -18.754 1.00 22.64  ? 391  LEU A N     1 
ATOM   3100  C CA    . LEU A 1 391 ? -53.257  -76.710  -19.867 1.00 22.07  ? 391  LEU A CA    1 
ATOM   3101  C C     . LEU A 1 391 ? -51.722  -76.759  -19.879 1.00 22.13  ? 391  LEU A C     1 
ATOM   3102  O O     . LEU A 1 391 ? -51.088  -76.554  -18.844 1.00 22.90  ? 391  LEU A O     1 
ATOM   3103  C CB    . LEU A 1 391 ? -53.763  -75.278  -19.685 1.00 18.77  ? 391  LEU A CB    1 
ATOM   3104  C CG    . LEU A 1 391 ? -53.157  -74.249  -20.652 1.00 19.98  ? 391  LEU A CG    1 
ATOM   3105  C CD1   . LEU A 1 391 ? -53.516  -74.566  -22.082 1.00 18.34  ? 391  LEU A CD1   1 
ATOM   3106  C CD2   . LEU A 1 391 ? -53.540  -72.803  -20.291 1.00 18.43  ? 391  LEU A CD2   1 
ATOM   3107  N N     . THR A 1 392 ? -51.127  -77.016  -21.050 1.00 20.08  ? 392  THR A N     1 
ATOM   3108  C CA    . THR A 1 392 ? -49.689  -76.966  -21.236 1.00 19.88  ? 392  THR A CA    1 
ATOM   3109  C C     . THR A 1 392 ? -49.397  -76.041  -22.408 1.00 20.35  ? 392  THR A C     1 
ATOM   3110  O O     . THR A 1 392 ? -49.937  -76.277  -23.478 1.00 26.36  ? 392  THR A O     1 
ATOM   3111  C CB    . THR A 1 392 ? -49.119  -78.354  -21.528 1.00 20.16  ? 392  THR A CB    1 
ATOM   3112  O OG1   . THR A 1 392 ? -49.512  -79.217  -20.458 1.00 19.80  ? 392  THR A OG1   1 
ATOM   3113  C CG2   . THR A 1 392 ? -47.603  -78.353  -21.654 1.00 16.92  ? 392  THR A CG2   1 
ATOM   3114  N N     . VAL A 1 393 ? -48.551  -75.016  -22.215 1.00 18.87  ? 393  VAL A N     1 
ATOM   3115  C CA    . VAL A 1 393 ? -48.151  -74.114  -23.273 1.00 19.26  ? 393  VAL A CA    1 
ATOM   3116  C C     . VAL A 1 393 ? -46.659  -74.272  -23.499 1.00 20.56  ? 393  VAL A C     1 
ATOM   3117  O O     . VAL A 1 393 ? -45.926  -74.642  -22.580 1.00 23.74  ? 393  VAL A O     1 
ATOM   3118  C CB    . VAL A 1 393 ? -48.468  -72.635  -22.988 1.00 20.72  ? 393  VAL A CB    1 
ATOM   3119  C CG1   . VAL A 1 393 ? -49.903  -72.451  -22.559 1.00 20.24  ? 393  VAL A CG1   1 
ATOM   3120  C CG2   . VAL A 1 393 ? -47.566  -72.114  -21.871 1.00 25.47  ? 393  VAL A CG2   1 
ATOM   3121  N N     . ASP A 1 394 ? -46.216  -73.979  -24.727 1.00 20.86  ? 394  ASP A N     1 
ATOM   3122  C CA    . ASP A 1 394 ? -44.797  -73.837  -24.984 1.00 21.68  ? 394  ASP A CA    1 
ATOM   3123  C C     . ASP A 1 394 ? -44.447  -72.376  -24.733 1.00 22.89  ? 394  ASP A C     1 
ATOM   3124  O O     . ASP A 1 394 ? -44.741  -71.511  -25.586 1.00 21.73  ? 394  ASP A O     1 
ATOM   3125  C CB    . ASP A 1 394 ? -44.430  -74.188  -26.422 1.00 21.59  ? 394  ASP A CB    1 
ATOM   3126  C CG    . ASP A 1 394 ? -42.963  -73.932  -26.777 1.00 26.55  ? 394  ASP A CG    1 
ATOM   3127  O OD1   . ASP A 1 394 ? -42.123  -73.669  -25.861 1.00 28.59  ? 394  ASP A OD1   1 
ATOM   3128  O OD2   . ASP A 1 394 ? -42.646  -73.917  -27.983 1.00 29.08  ? 394  ASP A OD2   1 
ATOM   3129  N N     . ALA A 1 395 ? -43.847  -72.102  -23.565 1.00 19.28  ? 395  ALA A N     1 
ATOM   3130  C CA    . ALA A 1 395 ? -43.591  -70.710  -23.191 1.00 18.80  ? 395  ALA A CA    1 
ATOM   3131  C C     . ALA A 1 395 ? -42.268  -70.257  -23.812 1.00 19.08  ? 395  ALA A C     1 
ATOM   3132  O O     . ALA A 1 395 ? -41.214  -70.459  -23.222 1.00 19.22  ? 395  ALA A O     1 
ATOM   3133  C CB    . ALA A 1 395 ? -43.624  -70.550  -21.680 1.00 15.48  ? 395  ALA A CB    1 
ATOM   3134  N N     . THR A 1 396 ? -42.316  -69.671  -25.007 1.00 18.06  ? 396  THR A N     1 
ATOM   3135  C CA    . THR A 1 396 ? -41.090  -69.315  -25.709 1.00 18.18  ? 396  THR A CA    1 
ATOM   3136  C C     . THR A 1 396 ? -40.333  -68.241  -24.927 1.00 18.50  ? 396  THR A C     1 
ATOM   3137  O O     . THR A 1 396 ? -40.926  -67.459  -24.176 1.00 18.75  ? 396  THR A O     1 
ATOM   3138  C CB    . THR A 1 396 ? -41.441  -68.867  -27.138 1.00 21.07  ? 396  THR A CB    1 
ATOM   3139  O OG1   . THR A 1 396 ? -42.422  -67.837  -27.017 1.00 21.63  ? 396  THR A OG1   1 
ATOM   3140  C CG2   . THR A 1 396 ? -42.008  -70.010  -27.976 1.00 19.15  ? 396  THR A CG2   1 
ATOM   3141  N N     . GLY A 1 397 ? -39.004  -68.217  -25.111 1.00 18.18  ? 397  GLY A N     1 
ATOM   3142  C CA    . GLY A 1 397 ? -38.142  -67.273  -24.442 1.00 17.14  ? 397  GLY A CA    1 
ATOM   3143  C C     . GLY A 1 397 ? -38.259  -65.868  -25.050 1.00 19.27  ? 397  GLY A C     1 
ATOM   3144  O O     . GLY A 1 397 ? -38.951  -65.652  -26.043 1.00 19.11  ? 397  GLY A O     1 
ATOM   3145  N N     . TYR A 1 398 ? -37.584  -64.903  -24.421 1.00 20.22  ? 398  TYR A N     1 
ATOM   3146  C CA    . TYR A 1 398 ? -37.673  -63.522  -24.841 1.00 20.09  ? 398  TYR A CA    1 
ATOM   3147  C C     . TYR A 1 398 ? -36.975  -63.322  -26.182 1.00 22.72  ? 398  TYR A C     1 
ATOM   3148  O O     . TYR A 1 398 ? -35.905  -63.875  -26.441 1.00 21.82  ? 398  TYR A O     1 
ATOM   3149  C CB    . TYR A 1 398 ? -37.019  -62.601  -23.808 1.00 19.12  ? 398  TYR A CB    1 
ATOM   3150  C CG    . TYR A 1 398 ? -37.671  -62.709  -22.437 1.00 20.02  ? 398  TYR A CG    1 
ATOM   3151  C CD1   . TYR A 1 398 ? -38.971  -62.257  -22.241 1.00 17.86  ? 398  TYR A CD1   1 
ATOM   3152  C CD2   . TYR A 1 398 ? -36.990  -63.257  -21.344 1.00 19.66  ? 398  TYR A CD2   1 
ATOM   3153  C CE1   . TYR A 1 398 ? -39.591  -62.333  -21.005 1.00 17.25  ? 398  TYR A CE1   1 
ATOM   3154  C CE2   . TYR A 1 398 ? -37.594  -63.342  -20.097 1.00 20.27  ? 398  TYR A CE2   1 
ATOM   3155  C CZ    . TYR A 1 398 ? -38.896  -62.875  -19.941 1.00 21.48  ? 398  TYR A CZ    1 
ATOM   3156  O OH    . TYR A 1 398 ? -39.553  -62.942  -18.745 1.00 25.62  ? 398  TYR A OH    1 
ATOM   3157  N N     . PRO A 1 399 ? -37.526  -62.458  -27.062 1.00 21.81  ? 399  PRO A N     1 
ATOM   3158  C CA    . PRO A 1 399 ? -36.747  -62.002  -28.205 1.00 21.50  ? 399  PRO A CA    1 
ATOM   3159  C C     . PRO A 1 399 ? -35.459  -61.342  -27.720 1.00 23.80  ? 399  PRO A C     1 
ATOM   3160  O O     . PRO A 1 399 ? -35.471  -60.591  -26.732 1.00 26.05  ? 399  PRO A O     1 
ATOM   3161  C CB    . PRO A 1 399 ? -37.624  -60.961  -28.905 1.00 19.63  ? 399  PRO A CB    1 
ATOM   3162  C CG    . PRO A 1 399 ? -38.981  -61.061  -28.251 1.00 22.93  ? 399  PRO A CG    1 
ATOM   3163  C CD    . PRO A 1 399 ? -38.868  -61.851  -26.949 1.00 21.69  ? 399  PRO A CD    1 
ATOM   3164  N N     . TYR A 1 400 ? -34.352  -61.625  -28.417 1.00 20.28  ? 400  TYR A N     1 
ATOM   3165  C CA    . TYR A 1 400 ? -33.088  -61.011  -28.076 1.00 18.45  ? 400  TYR A CA    1 
ATOM   3166  C C     . TYR A 1 400 ? -33.311  -59.511  -27.961 1.00 21.86  ? 400  TYR A C     1 
ATOM   3167  O O     . TYR A 1 400 ? -34.051  -58.917  -28.760 1.00 19.96  ? 400  TYR A O     1 
ATOM   3168  C CB    . TYR A 1 400 ? -32.022  -61.374  -29.108 1.00 17.54  ? 400  TYR A CB    1 
ATOM   3169  C CG    . TYR A 1 400 ? -30.706  -60.664  -28.846 1.00 18.62  ? 400  TYR A CG    1 
ATOM   3170  C CD1   . TYR A 1 400 ? -29.813  -61.111  -27.853 1.00 17.20  ? 400  TYR A CD1   1 
ATOM   3171  C CD2   . TYR A 1 400 ? -30.375  -59.511  -29.556 1.00 16.90  ? 400  TYR A CD2   1 
ATOM   3172  C CE1   . TYR A 1 400 ? -28.627  -60.443  -27.583 1.00 15.71  ? 400  TYR A CE1   1 
ATOM   3173  C CE2   . TYR A 1 400 ? -29.166  -58.865  -29.336 1.00 16.30  ? 400  TYR A CE2   1 
ATOM   3174  C CZ    . TYR A 1 400 ? -28.310  -59.311  -28.329 1.00 17.82  ? 400  TYR A CZ    1 
ATOM   3175  O OH    . TYR A 1 400 ? -27.137  -58.616  -28.152 1.00 17.63  ? 400  TYR A OH    1 
ATOM   3176  N N     . GLY A 1 401 ? -32.687  -58.913  -26.937 1.00 20.93  ? 401  GLY A N     1 
ATOM   3177  C CA    . GLY A 1 401 ? -32.813  -57.483  -26.761 1.00 19.07  ? 401  GLY A CA    1 
ATOM   3178  C C     . GLY A 1 401 ? -33.890  -57.145  -25.739 1.00 21.30  ? 401  GLY A C     1 
ATOM   3179  O O     . GLY A 1 401 ? -34.087  -55.957  -25.425 1.00 22.68  ? 401  GLY A O     1 
ATOM   3180  N N     . SER A 1 402 ? -34.595  -58.158  -25.210 1.00 18.80  ? 402  SER A N     1 
ATOM   3181  C CA    . SER A 1 402 ? -35.603  -57.775  -24.225 1.00 22.92  ? 402  SER A CA    1 
ATOM   3182  C C     . SER A 1 402 ? -35.722  -58.848  -23.150 1.00 22.78  ? 402  SER A C     1 
ATOM   3183  O O     . SER A 1 402 ? -35.204  -59.950  -23.317 1.00 21.90  ? 402  SER A O     1 
ATOM   3184  C CB    . SER A 1 402 ? -36.938  -57.450  -24.922 1.00 29.72  ? 402  SER A CB    1 
ATOM   3185  O OG    . SER A 1 402 ? -37.522  -58.680  -25.306 1.00 36.85  ? 402  SER A OG    1 
ATOM   3186  N N     . ASP A 1 403 ? -36.328  -58.514  -21.998 1.00 22.37  ? 403  ASP A N     1 
ATOM   3187  C CA    . ASP A 1 403 ? -36.457  -59.447  -20.874 1.00 19.95  ? 403  ASP A CA    1 
ATOM   3188  C C     . ASP A 1 403 ? -37.400  -58.809  -19.857 1.00 19.90  ? 403  ASP A C     1 
ATOM   3189  O O     . ASP A 1 403 ? -37.030  -57.840  -19.177 1.00 20.87  ? 403  ASP A O     1 
ATOM   3190  C CB    . ASP A 1 403 ? -35.097  -59.780  -20.260 1.00 20.94  ? 403  ASP A CB    1 
ATOM   3191  C CG    . ASP A 1 403 ? -35.115  -60.837  -19.147 1.00 25.44  ? 403  ASP A CG    1 
ATOM   3192  O OD1   . ASP A 1 403 ? -36.183  -61.001  -18.498 1.00 25.08  ? 403  ASP A OD1   1 
ATOM   3193  O OD2   . ASP A 1 403 ? -34.079  -61.536  -18.922 1.00 24.49  ? 403  ASP A OD2   1 
ATOM   3194  N N     . TRP A 1 404 ? -38.610  -59.368  -19.736 1.00 20.40  ? 404  TRP A N     1 
ATOM   3195  C CA    . TRP A 1 404 ? -39.703  -58.730  -18.997 1.00 18.76  ? 404  TRP A CA    1 
ATOM   3196  C C     . TRP A 1 404 ? -39.751  -59.209  -17.540 1.00 20.13  ? 404  TRP A C     1 
ATOM   3197  O O     . TRP A 1 404 ? -40.571  -58.713  -16.761 1.00 20.60  ? 404  TRP A O     1 
ATOM   3198  C CB    . TRP A 1 404 ? -41.040  -58.955  -19.720 1.00 16.81  ? 404  TRP A CB    1 
ATOM   3199  C CG    . TRP A 1 404 ? -41.086  -58.244  -21.052 1.00 19.50  ? 404  TRP A CG    1 
ATOM   3200  C CD1   . TRP A 1 404 ? -40.757  -58.765  -22.275 1.00 18.38  ? 404  TRP A CD1   1 
ATOM   3201  C CD2   . TRP A 1 404 ? -41.462  -56.865  -21.291 1.00 18.69  ? 404  TRP A CD2   1 
ATOM   3202  N NE1   . TRP A 1 404 ? -40.891  -57.814  -23.249 1.00 19.67  ? 404  TRP A NE1   1 
ATOM   3203  C CE2   . TRP A 1 404 ? -41.332  -56.638  -22.683 1.00 18.71  ? 404  TRP A CE2   1 
ATOM   3204  C CE3   . TRP A 1 404 ? -41.910  -55.809  -20.480 1.00 19.66  ? 404  TRP A CE3   1 
ATOM   3205  C CZ2   . TRP A 1 404 ? -41.633  -55.408  -23.277 1.00 15.93  ? 404  TRP A CZ2   1 
ATOM   3206  C CZ3   . TRP A 1 404 ? -42.184  -54.573  -21.059 1.00 19.55  ? 404  TRP A CZ3   1 
ATOM   3207  C CH2   . TRP A 1 404 ? -42.044  -54.386  -22.446 1.00 18.32  ? 404  TRP A CH2   1 
ATOM   3208  N N     . VAL A 1 405 ? -38.925  -60.213  -17.184 1.00 19.01  ? 405  VAL A N     1 
ATOM   3209  C CA    . VAL A 1 405 ? -38.864  -60.750  -15.832 1.00 18.18  ? 405  VAL A CA    1 
ATOM   3210  C C     . VAL A 1 405 ? -40.116  -61.575  -15.509 1.00 17.79  ? 405  VAL A C     1 
ATOM   3211  O O     . VAL A 1 405 ? -39.993  -62.735  -15.135 1.00 20.09  ? 405  VAL A O     1 
ATOM   3212  C CB    . VAL A 1 405 ? -38.602  -59.703  -14.715 1.00 19.31  ? 405  VAL A CB    1 
ATOM   3213  C CG1   . VAL A 1 405 ? -38.539  -60.346  -13.333 1.00 17.36  ? 405  VAL A CG1   1 
ATOM   3214  C CG2   . VAL A 1 405 ? -37.357  -58.881  -14.990 1.00 18.28  ? 405  VAL A CG2   1 
ATOM   3215  N N     . VAL A 1 406 ? -41.305  -60.965  -15.541 1.00 18.83  ? 406  VAL A N     1 
ATOM   3216  C CA    . VAL A 1 406 ? -42.555  -61.722  -15.463 1.00 18.23  ? 406  VAL A CA    1 
ATOM   3217  C C     . VAL A 1 406 ? -43.260  -61.509  -16.799 1.00 19.30  ? 406  VAL A C     1 
ATOM   3218  O O     . VAL A 1 406 ? -43.649  -60.378  -17.119 1.00 21.20  ? 406  VAL A O     1 
ATOM   3219  C CB    . VAL A 1 406 ? -43.471  -61.263  -14.304 1.00 18.42  ? 406  VAL A CB    1 
ATOM   3220  C CG1   . VAL A 1 406 ? -44.842  -61.939  -14.326 1.00 15.52  ? 406  VAL A CG1   1 
ATOM   3221  C CG2   . VAL A 1 406 ? -42.808  -61.418  -12.927 1.00 15.49  ? 406  VAL A CG2   1 
ATOM   3222  N N     . ARG A 1 407 ? -43.390  -62.578  -17.600 1.00 18.40  ? 407  ARG A N     1 
ATOM   3223  C CA    . ARG A 1 407 ? -44.010  -62.458  -18.920 1.00 17.15  ? 407  ARG A CA    1 
ATOM   3224  C C     . ARG A 1 407 ? -45.476  -62.897  -18.812 1.00 19.39  ? 407  ARG A C     1 
ATOM   3225  O O     . ARG A 1 407 ? -45.795  -63.808  -18.031 1.00 19.24  ? 407  ARG A O     1 
ATOM   3226  C CB    . ARG A 1 407 ? -43.237  -63.326  -19.916 1.00 14.87  ? 407  ARG A CB    1 
ATOM   3227  C CG    . ARG A 1 407 ? -43.335  -62.805  -21.343 1.00 16.95  ? 407  ARG A CG    1 
ATOM   3228  C CD    . ARG A 1 407 ? -42.644  -63.728  -22.361 1.00 16.41  ? 407  ARG A CD    1 
ATOM   3229  N NE    . ARG A 1 407 ? -42.661  -63.036  -23.639 1.00 17.26  ? 407  ARG A NE    1 
ATOM   3230  C CZ    . ARG A 1 407 ? -42.080  -63.474  -24.754 1.00 20.56  ? 407  ARG A CZ    1 
ATOM   3231  N NH1   . ARG A 1 407 ? -41.473  -64.674  -24.787 1.00 17.88  ? 407  ARG A NH1   1 
ATOM   3232  N NH2   . ARG A 1 407 ? -42.128  -62.698  -25.843 1.00 18.32  ? 407  ARG A NH2   1 
ATOM   3233  N N     . ILE A 1 408 ? -46.373  -62.250  -19.571 1.00 18.08  ? 408  ILE A N     1 
ATOM   3234  C CA    . ILE A 1 408 ? -47.800  -62.509  -19.393 1.00 18.20  ? 408  ILE A CA    1 
ATOM   3235  C C     . ILE A 1 408 ? -48.423  -62.954  -20.715 1.00 20.25  ? 408  ILE A C     1 
ATOM   3236  O O     . ILE A 1 408 ? -48.318  -62.261  -21.723 1.00 21.90  ? 408  ILE A O     1 
ATOM   3237  C CB    . ILE A 1 408 ? -48.505  -61.257  -18.835 1.00 17.52  ? 408  ILE A CB    1 
ATOM   3238  C CG1   . ILE A 1 408 ? -47.879  -60.811  -17.485 1.00 17.78  ? 408  ILE A CG1   1 
ATOM   3239  C CG2   . ILE A 1 408 ? -50.003  -61.501  -18.692 1.00 15.78  ? 408  ILE A CG2   1 
ATOM   3240  C CD1   . ILE A 1 408 ? -48.406  -59.490  -16.956 1.00 17.34  ? 408  ILE A CD1   1 
ATOM   3241  N N     . ALA A 1 409 ? -49.097  -64.101  -20.703 1.00 20.70  ? 409  ALA A N     1 
ATOM   3242  C CA    . ALA A 1 409 ? -49.814  -64.618  -21.871 1.00 21.94  ? 409  ALA A CA    1 
ATOM   3243  C C     . ALA A 1 409 ? -51.319  -64.502  -21.617 1.00 27.35  ? 409  ALA A C     1 
ATOM   3244  O O     . ALA A 1 409 ? -51.817  -64.917  -20.554 1.00 27.39  ? 409  ALA A O     1 
ATOM   3245  C CB    . ALA A 1 409 ? -49.433  -66.078  -22.125 1.00 17.16  ? 409  ALA A CB    1 
ATOM   3246  N N     . GLN A 1 410 ? -52.031  -63.920  -22.587 1.00 26.61  ? 410  GLN A N     1 
ATOM   3247  C CA    . GLN A 1 410 ? -53.479  -63.795  -22.494 1.00 25.55  ? 410  GLN A CA    1 
ATOM   3248  C C     . GLN A 1 410 ? -54.148  -64.991  -23.166 1.00 25.76  ? 410  GLN A C     1 
ATOM   3249  O O     . GLN A 1 410 ? -53.785  -65.390  -24.290 1.00 24.23  ? 410  GLN A O     1 
ATOM   3250  C CB    . GLN A 1 410 ? -53.938  -62.565  -23.268 1.00 25.77  ? 410  GLN A CB    1 
ATOM   3251  C CG    . GLN A 1 410 ? -55.433  -62.307  -23.159 1.00 27.14  ? 410  GLN A CG    1 
ATOM   3252  C CD    . GLN A 1 410 ? -55.830  -61.020  -23.835 1.00 28.39  ? 410  GLN A CD    1 
ATOM   3253  O OE1   . GLN A 1 410 ? -55.331  -59.940  -23.493 1.00 34.24  ? 410  GLN A OE1   1 
ATOM   3254  N NE2   . GLN A 1 410 ? -56.693  -61.127  -24.835 1.00 23.82  ? 410  GLN A NE2   1 
ATOM   3255  N N     . ILE A 1 411 ? -55.115  -65.567  -22.448 1.00 24.36  ? 411  ILE A N     1 
ATOM   3256  C CA    . ILE A 1 411 ? -55.925  -66.665  -22.950 1.00 25.35  ? 411  ILE A CA    1 
ATOM   3257  C C     . ILE A 1 411 ? -57.250  -66.120  -23.484 1.00 27.93  ? 411  ILE A C     1 
ATOM   3258  O O     . ILE A 1 411 ? -57.977  -65.427  -22.753 1.00 29.65  ? 411  ILE A O     1 
ATOM   3259  C CB    . ILE A 1 411 ? -56.186  -67.674  -21.820 1.00 22.61  ? 411  ILE A CB    1 
ATOM   3260  C CG1   . ILE A 1 411 ? -54.863  -68.351  -21.354 1.00 19.44  ? 411  ILE A CG1   1 
ATOM   3261  C CG2   . ILE A 1 411 ? -57.225  -68.693  -22.300 1.00 24.33  ? 411  ILE A CG2   1 
ATOM   3262  C CD1   . ILE A 1 411 ? -55.024  -69.216  -20.116 1.00 19.38  ? 411  ILE A CD1   1 
ATOM   3263  N N     . ASP A 1 412 ? -57.564  -66.457  -24.747 1.00 25.70  ? 412  ASP A N     1 
ATOM   3264  C CA    . ASP A 1 412 ? -58.863  -66.177  -25.362 1.00 26.90  ? 412  ASP A CA    1 
ATOM   3265  C C     . ASP A 1 412 ? -59.635  -67.496  -25.461 1.00 25.88  ? 412  ASP A C     1 
ATOM   3266  O O     . ASP A 1 412 ? -59.189  -68.446  -26.128 1.00 23.95  ? 412  ASP A O     1 
ATOM   3267  C CB    . ASP A 1 412 ? -58.684  -65.593  -26.761 1.00 22.89  ? 412  ASP A CB    1 
ATOM   3268  C CG    . ASP A 1 412 ? -57.953  -64.258  -26.779 1.00 32.22  ? 412  ASP A CG    1 
ATOM   3269  O OD1   . ASP A 1 412 ? -57.856  -63.622  -25.688 1.00 34.83  ? 412  ASP A OD1   1 
ATOM   3270  O OD2   . ASP A 1 412 ? -57.423  -63.882  -27.864 1.00 35.94  ? 412  ASP A OD2   1 
ATOM   3271  N N     . TYR A 1 413 ? -60.783  -67.543  -24.775 1.00 25.13  ? 413  TYR A N     1 
ATOM   3272  C CA    . TYR A 1 413 ? -61.615  -68.740  -24.787 1.00 32.64  ? 413  TYR A CA    1 
ATOM   3273  C C     . TYR A 1 413 ? -62.479  -68.812  -26.040 1.00 34.56  ? 413  TYR A C     1 
ATOM   3274  O O     . TYR A 1 413 ? -62.802  -67.795  -26.638 1.00 35.68  ? 413  TYR A O     1 
ATOM   3275  C CB    . TYR A 1 413 ? -62.499  -68.766  -23.546 1.00 26.03  ? 413  TYR A CB    1 
ATOM   3276  C CG    . TYR A 1 413 ? -61.648  -69.098  -22.330 1.00 29.60  ? 413  TYR A CG    1 
ATOM   3277  C CD1   . TYR A 1 413 ? -61.160  -70.385  -22.144 1.00 28.27  ? 413  TYR A CD1   1 
ATOM   3278  C CD2   . TYR A 1 413 ? -61.284  -68.112  -21.409 1.00 28.09  ? 413  TYR A CD2   1 
ATOM   3279  C CE1   . TYR A 1 413 ? -60.372  -70.700  -21.053 1.00 30.92  ? 413  TYR A CE1   1 
ATOM   3280  C CE2   . TYR A 1 413 ? -60.525  -68.421  -20.295 1.00 29.48  ? 413  TYR A CE2   1 
ATOM   3281  C CZ    . TYR A 1 413 ? -60.046  -69.710  -20.127 1.00 32.25  ? 413  TYR A CZ    1 
ATOM   3282  O OH    . TYR A 1 413 ? -59.267  -70.034  -19.036 1.00 27.72  ? 413  TYR A OH    1 
ATOM   3283  N N     . GLU A 1 414 ? -62.812  -70.047  -26.430 1.00 44.32  ? 414  GLU A N     1 
ATOM   3284  C CA    . GLU A 1 414 ? -63.785  -70.322  -27.472 1.00 53.48  ? 414  GLU A CA    1 
ATOM   3285  C C     . GLU A 1 414 ? -65.185  -69.861  -27.042 1.00 61.05  ? 414  GLU A C     1 
ATOM   3286  O O     . GLU A 1 414 ? -65.928  -69.502  -27.991 1.00 62.74  ? 414  GLU A O     1 
ATOM   3287  C CB    . GLU A 1 414 ? -63.823  -71.790  -27.882 1.00 50.84  ? 414  GLU A CB    1 
ATOM   3288  C CG    . GLU A 1 414 ? -62.657  -72.147  -28.789 1.00 61.91  ? 414  GLU A CG    1 
ATOM   3289  C CD    . GLU A 1 414 ? -62.815  -73.517  -29.436 1.00 88.77  ? 414  GLU A CD    1 
ATOM   3290  O OE1   . GLU A 1 414 ? -62.183  -73.705  -30.510 1.00 94.94  ? 414  GLU A OE1   1 
ATOM   3291  O OE2   . GLU A 1 414 ? -63.550  -74.385  -28.879 1.00 82.78  ? 414  GLU A OE2   1 
ATOM   3292  O OXT   . GLU A 1 414 ? -65.478  -69.883  -25.797 1.00 57.03  ? 414  GLU A OXT   1 
ATOM   3293  N N     . MET B 1 1   ? 5.056    -69.274  -8.959  1.00 57.32  ? 1    MET B N     1 
ATOM   3294  C CA    . MET B 1 1   ? 6.507    -69.210  -9.304  1.00 68.60  ? 1    MET B CA    1 
ATOM   3295  C C     . MET B 1 1   ? 6.881    -67.849  -9.918  1.00 59.19  ? 1    MET B C     1 
ATOM   3296  O O     . MET B 1 1   ? 7.532    -67.054  -9.235  1.00 44.56  ? 1    MET B O     1 
ATOM   3297  C CB    . MET B 1 1   ? 6.948    -70.396  -10.177 1.00 97.63  ? 1    MET B CB    1 
ATOM   3298  C CG    . MET B 1 1   ? 8.467    -70.557  -10.327 1.00 109.73 ? 1    MET B CG    1 
ATOM   3299  S SD    . MET B 1 1   ? 9.248    -71.732  -9.200  1.00 118.31 ? 1    MET B SD    1 
ATOM   3300  C CE    . MET B 1 1   ? 8.544    -73.313  -9.709  1.00 95.23  ? 1    MET B CE    1 
ATOM   3301  N N     . THR B 1 2   ? 6.507    -67.545  -11.184 1.00 47.22  ? 2    THR B N     1 
ATOM   3302  C CA    . THR B 1 2   ? 6.907    -66.227  -11.679 1.00 38.99  ? 2    THR B CA    1 
ATOM   3303  C C     . THR B 1 2   ? 5.952    -65.168  -11.130 1.00 37.97  ? 2    THR B C     1 
ATOM   3304  O O     . THR B 1 2   ? 4.828    -65.485  -10.762 1.00 34.03  ? 2    THR B O     1 
ATOM   3305  C CB    . THR B 1 2   ? 7.021    -66.078  -13.196 1.00 39.01  ? 2    THR B CB    1 
ATOM   3306  O OG1   . THR B 1 2   ? 5.712    -66.370  -13.657 1.00 36.05  ? 2    THR B OG1   1 
ATOM   3307  C CG2   . THR B 1 2   ? 7.956    -67.072  -13.869 1.00 36.14  ? 2    THR B CG2   1 
ATOM   3308  N N     . GLU B 1 3   ? 6.440    -63.936  -11.084 1.00 32.90  ? 3    GLU B N     1 
ATOM   3309  C CA    . GLU B 1 3   ? 5.708    -62.790  -10.628 1.00 32.85  ? 3    GLU B CA    1 
ATOM   3310  C C     . GLU B 1 3   ? 5.370    -61.898  -11.817 1.00 34.56  ? 3    GLU B C     1 
ATOM   3311  O O     . GLU B 1 3   ? 5.965    -61.996  -12.891 1.00 32.19  ? 3    GLU B O     1 
ATOM   3312  C CB    . GLU B 1 3   ? 6.591    -62.052  -9.627  1.00 37.90  ? 3    GLU B CB    1 
ATOM   3313  C CG    . GLU B 1 3   ? 6.266    -62.635  -8.253  1.00 60.23  ? 3    GLU B CG    1 
ATOM   3314  C CD    . GLU B 1 3   ? 7.096    -62.136  -7.086  1.00 75.31  ? 3    GLU B CD    1 
ATOM   3315  O OE1   . GLU B 1 3   ? 8.316    -61.977  -7.317  1.00 81.90  ? 3    GLU B OE1   1 
ATOM   3316  O OE2   . GLU B 1 3   ? 6.552    -61.927  -5.973  1.00 87.15  ? 3    GLU B OE2   1 
ATOM   3317  N N     . PRO B 1 4   ? 4.352    -61.023  -11.682 1.00 30.75  ? 4    PRO B N     1 
ATOM   3318  C CA    . PRO B 1 4   ? 3.934    -60.214  -12.817 1.00 23.80  ? 4    PRO B CA    1 
ATOM   3319  C C     . PRO B 1 4   ? 5.004    -59.265  -13.321 1.00 25.62  ? 4    PRO B C     1 
ATOM   3320  O O     . PRO B 1 4   ? 5.654    -58.626  -12.525 1.00 27.71  ? 4    PRO B O     1 
ATOM   3321  C CB    . PRO B 1 4   ? 2.703    -59.492  -12.308 1.00 24.13  ? 4    PRO B CB    1 
ATOM   3322  C CG    . PRO B 1 4   ? 2.710    -59.665  -10.795 1.00 25.25  ? 4    PRO B CG    1 
ATOM   3323  C CD    . PRO B 1 4   ? 3.479    -60.902  -10.488 1.00 27.19  ? 4    PRO B CD    1 
ATOM   3324  N N     . LEU B 1 5   ? 5.100    -59.102  -14.612 1.00 23.98  ? 5    LEU B N     1 
ATOM   3325  C CA    . LEU B 1 5   ? 5.966    -58.102  -15.161 1.00 23.99  ? 5    LEU B CA    1 
ATOM   3326  C C     . LEU B 1 5   ? 5.389    -56.755  -14.744 1.00 24.76  ? 5    LEU B C     1 
ATOM   3327  O O     . LEU B 1 5   ? 4.258    -56.652  -14.409 1.00 26.36  ? 5    LEU B O     1 
ATOM   3328  C CB    . LEU B 1 5   ? 6.049    -58.224  -16.660 1.00 24.05  ? 5    LEU B CB    1 
ATOM   3329  C CG    . LEU B 1 5   ? 6.775    -59.422  -17.201 1.00 23.33  ? 5    LEU B CG    1 
ATOM   3330  C CD1   . LEU B 1 5   ? 6.444    -59.627  -18.647 1.00 23.09  ? 5    LEU B CD1   1 
ATOM   3331  C CD2   . LEU B 1 5   ? 8.260    -59.326  -16.957 1.00 23.47  ? 5    LEU B CD2   1 
ATOM   3332  N N     . PRO B 1 6   ? 6.184    -55.710  -14.759 1.00 27.00  ? 6    PRO B N     1 
ATOM   3333  C CA    . PRO B 1 6   ? 5.673    -54.442  -14.248 1.00 25.15  ? 6    PRO B CA    1 
ATOM   3334  C C     . PRO B 1 6   ? 4.407    -53.871  -14.884 1.00 25.90  ? 6    PRO B C     1 
ATOM   3335  O O     . PRO B 1 6   ? 3.665    -53.332  -14.149 1.00 24.50  ? 6    PRO B O     1 
ATOM   3336  C CB    . PRO B 1 6   ? 6.867    -53.515  -14.392 1.00 23.65  ? 6    PRO B CB    1 
ATOM   3337  C CG    . PRO B 1 6   ? 8.009    -54.406  -14.252 1.00 23.24  ? 6    PRO B CG    1 
ATOM   3338  C CD    . PRO B 1 6   ? 7.640    -55.684  -14.899 1.00 26.88  ? 6    PRO B CD    1 
ATOM   3339  N N     . ARG B 1 7   ? 4.159    -54.001  -16.166 1.00 24.81  ? 7    ARG B N     1 
ATOM   3340  C CA    . ARG B 1 7   ? 2.936    -53.473  -16.722 1.00 25.78  ? 7    ARG B CA    1 
ATOM   3341  C C     . ARG B 1 7   ? 1.698    -54.177  -16.180 1.00 26.16  ? 7    ARG B C     1 
ATOM   3342  O O     . ARG B 1 7   ? 0.709    -53.565  -16.011 1.00 23.53  ? 7    ARG B O     1 
ATOM   3343  C CB    . ARG B 1 7   ? 2.968    -53.343  -18.249 1.00 25.40  ? 7    ARG B CB    1 
ATOM   3344  C CG    . ARG B 1 7   ? 2.919    -54.620  -18.995 1.00 22.41  ? 7    ARG B CG    1 
ATOM   3345  C CD    . ARG B 1 7   ? 2.776    -54.474  -20.478 1.00 23.97  ? 7    ARG B CD    1 
ATOM   3346  N NE    . ARG B 1 7   ? 2.833    -55.798  -21.031 1.00 25.67  ? 7    ARG B NE    1 
ATOM   3347  C CZ    . ARG B 1 7   ? 3.936    -56.446  -21.303 1.00 24.37  ? 7    ARG B CZ    1 
ATOM   3348  N NH1   . ARG B 1 7   ? 5.073    -55.862  -21.159 1.00 21.00  ? 7    ARG B NH1   1 
ATOM   3349  N NH2   . ARG B 1 7   ? 3.883    -57.656  -21.752 1.00 21.20  ? 7    ARG B NH2   1 
ATOM   3350  N N     . ILE B 1 8   ? 1.798    -55.480  -15.985 1.00 25.42  ? 8    ILE B N     1 
ATOM   3351  C CA    . ILE B 1 8   ? 0.794    -56.352  -15.414 1.00 24.23  ? 8    ILE B CA    1 
ATOM   3352  C C     . ILE B 1 8   ? 0.561    -56.036  -13.947 1.00 25.32  ? 8    ILE B C     1 
ATOM   3353  O O     . ILE B 1 8   ? -0.512   -56.095  -13.476 1.00 26.62  ? 8    ILE B O     1 
ATOM   3354  C CB    . ILE B 1 8   ? 1.118    -57.820  -15.707 1.00 23.09  ? 8    ILE B CB    1 
ATOM   3355  C CG1   . ILE B 1 8   ? 0.955    -58.051  -17.182 1.00 22.60  ? 8    ILE B CG1   1 
ATOM   3356  C CG2   . ILE B 1 8   ? 0.216    -58.764  -14.962 1.00 22.15  ? 8    ILE B CG2   1 
ATOM   3357  C CD1   . ILE B 1 8   ? 1.598    -59.290  -17.701 1.00 22.88  ? 8    ILE B CD1   1 
ATOM   3358  N N     . GLN B 1 9   ? 1.611    -55.717  -13.232 1.00 26.65  ? 9    GLN B N     1 
ATOM   3359  C CA    . GLN B 1 9   ? 1.515    -55.324  -11.851 1.00 27.99  ? 9    GLN B CA    1 
ATOM   3360  C C     . GLN B 1 9   ? 0.712    -54.035  -11.756 1.00 26.47  ? 9    GLN B C     1 
ATOM   3361  O O     . GLN B 1 9   ? -0.078   -53.888  -10.890 1.00 29.15  ? 9    GLN B O     1 
ATOM   3362  C CB    . GLN B 1 9   ? 2.906    -55.117  -11.289 1.00 35.34  ? 9    GLN B CB    1 
ATOM   3363  C CG    . GLN B 1 9   ? 3.076    -55.266  -9.808  1.00 54.30  ? 9    GLN B CG    1 
ATOM   3364  C CD    . GLN B 1 9   ? 2.609    -54.079  -8.985  1.00 74.45  ? 9    GLN B CD    1 
ATOM   3365  O OE1   . GLN B 1 9   ? 2.074    -54.259  -7.910  1.00 90.34  ? 9    GLN B OE1   1 
ATOM   3366  N NE2   . GLN B 1 9   ? 2.828    -52.875  -9.473  1.00 64.34  ? 9    GLN B NE2   1 
ATOM   3367  N N     . HIS B 1 10  ? 0.957    -53.099  -12.647 1.00 23.45  ? 10   HIS B N     1 
ATOM   3368  C CA    . HIS B 1 10  ? 0.229    -51.868  -12.730 1.00 26.83  ? 10   HIS B CA    1 
ATOM   3369  C C     . HIS B 1 10  ? -1.217   -52.125  -13.126 1.00 27.54  ? 10   HIS B C     1 
ATOM   3370  O O     . HIS B 1 10  ? -2.096   -51.432  -12.687 1.00 25.29  ? 10   HIS B O     1 
ATOM   3371  C CB    . HIS B 1 10  ? 0.895    -50.861  -13.652 1.00 31.41  ? 10   HIS B CB    1 
ATOM   3372  C CG    . HIS B 1 10  ? 0.174    -49.557  -13.727 1.00 63.23  ? 10   HIS B CG    1 
ATOM   3373  N ND1   . HIS B 1 10  ? 0.026    -48.731  -12.637 1.00 80.08  ? 10   HIS B ND1   1 
ATOM   3374  C CD2   . HIS B 1 10  ? -0.488   -48.955  -14.739 1.00 71.08  ? 10   HIS B CD2   1 
ATOM   3375  C CE1   . HIS B 1 10  ? -0.676   -47.674  -12.980 1.00 67.49  ? 10   HIS B CE1   1 
ATOM   3376  N NE2   . HIS B 1 10  ? -0.987   -47.776  -14.253 1.00 66.37  ? 10   HIS B NE2   1 
ATOM   3377  N N     . TYR B 1 11  ? -1.417   -53.110  -13.991 1.00 21.48  ? 11   TYR B N     1 
ATOM   3378  C CA    . TYR B 1 11  ? -2.757   -53.466  -14.420 1.00 22.84  ? 11   TYR B CA    1 
ATOM   3379  C C     . TYR B 1 11  ? -3.577   -53.962  -13.215 1.00 24.69  ? 11   TYR B C     1 
ATOM   3380  O O     . TYR B 1 11  ? -4.710   -53.530  -13.022 1.00 22.41  ? 11   TYR B O     1 
ATOM   3381  C CB    . TYR B 1 11  ? -2.701   -54.507  -15.534 1.00 19.03  ? 11   TYR B CB    1 
ATOM   3382  C CG    . TYR B 1 11  ? -4.076   -55.089  -15.837 1.00 20.53  ? 11   TYR B CG    1 
ATOM   3383  C CD1   . TYR B 1 11  ? -4.995   -54.411  -16.648 1.00 20.20  ? 11   TYR B CD1   1 
ATOM   3384  C CD2   . TYR B 1 11  ? -4.468   -56.296  -15.255 1.00 21.00  ? 11   TYR B CD2   1 
ATOM   3385  C CE1   . TYR B 1 11  ? -6.250   -54.933  -16.904 1.00 20.23  ? 11   TYR B CE1   1 
ATOM   3386  C CE2   . TYR B 1 11  ? -5.742   -56.812  -15.467 1.00 24.22  ? 11   TYR B CE2   1 
ATOM   3387  C CZ    . TYR B 1 11  ? -6.624   -56.134  -16.305 1.00 24.36  ? 11   TYR B CZ    1 
ATOM   3388  O OH    . TYR B 1 11  ? -7.865   -56.670  -16.512 1.00 24.71  ? 11   TYR B OH    1 
ATOM   3389  N N     . GLU B 1 12  ? -2.992   -54.849  -12.397 1.00 20.33  ? 12   GLU B N     1 
ATOM   3390  C CA    . GLU B 1 12  ? -3.685   -55.402  -11.255 1.00 25.52  ? 12   GLU B CA    1 
ATOM   3391  C C     . GLU B 1 12  ? -4.012   -54.301  -10.234 1.00 27.43  ? 12   GLU B C     1 
ATOM   3392  O O     . GLU B 1 12  ? -4.955   -54.448  -9.463  1.00 25.70  ? 12   GLU B O     1 
ATOM   3393  C CB    . GLU B 1 12  ? -2.939   -56.582  -10.624 1.00 24.68  ? 12   GLU B CB    1 
ATOM   3394  C CG    . GLU B 1 12  ? -2.702   -57.728  -11.602 1.00 26.06  ? 12   GLU B CG    1 
ATOM   3395  C CD    . GLU B 1 12  ? -2.150   -59.004  -10.958 1.00 31.57  ? 12   GLU B CD    1 
ATOM   3396  O OE1   . GLU B 1 12  ? -1.194   -58.896  -10.166 1.00 38.34  ? 12   GLU B OE1   1 
ATOM   3397  O OE2   . GLU B 1 12  ? -2.670   -60.112  -11.197 1.00 31.60  ? 12   GLU B OE2   1 
ATOM   3398  N N     . ASP B 1 13  ? -3.251   -53.201  -10.236 1.00 23.65  ? 13   ASP B N     1 
ATOM   3399  C CA    . ASP B 1 13  ? -3.513   -52.105  -9.321  1.00 25.17  ? 13   ASP B CA    1 
ATOM   3400  C C     . ASP B 1 13  ? -4.676   -51.249  -9.809  1.00 26.43  ? 13   ASP B C     1 
ATOM   3401  O O     . ASP B 1 13  ? -5.147   -50.396  -9.065  1.00 26.98  ? 13   ASP B O     1 
ATOM   3402  C CB    . ASP B 1 13  ? -2.318   -51.176  -9.156  1.00 26.99  ? 13   ASP B CB    1 
ATOM   3403  C CG    . ASP B 1 13  ? -1.236   -51.640  -8.195  1.00 31.85  ? 13   ASP B CG    1 
ATOM   3404  O OD1   . ASP B 1 13  ? -1.481   -52.613  -7.430  1.00 31.72  ? 13   ASP B OD1   1 
ATOM   3405  O OD2   . ASP B 1 13  ? -0.133   -51.031  -8.234  1.00 35.11  ? 13   ASP B OD2   1 
ATOM   3406  N N     . LEU B 1 14  ? -5.080   -51.414  -11.075 1.00 24.21  ? 14   LEU B N     1 
ATOM   3407  C CA    . LEU B 1 14  ? -6.186   -50.620  -11.592 1.00 22.83  ? 14   LEU B CA    1 
ATOM   3408  C C     . LEU B 1 14  ? -7.480   -51.030  -10.881 1.00 22.76  ? 14   LEU B C     1 
ATOM   3409  O O     . LEU B 1 14  ? -8.305   -50.175  -10.550 1.00 19.04  ? 14   LEU B O     1 
ATOM   3410  C CB    . LEU B 1 14  ? -6.292   -50.809  -13.101 1.00 21.61  ? 14   LEU B CB    1 
ATOM   3411  C CG    . LEU B 1 14  ? -5.071   -50.370  -13.925 1.00 21.34  ? 14   LEU B CG    1 
ATOM   3412  C CD1   . LEU B 1 14  ? -5.369   -50.767  -15.369 1.00 16.43  ? 14   LEU B CD1   1 
ATOM   3413  C CD2   . LEU B 1 14  ? -4.788   -48.844  -13.794 1.00 18.08  ? 14   LEU B CD2   1 
ATOM   3414  N N     . GLY B 1 15  ? -7.653   -52.347  -10.670 1.00 22.48  ? 15   GLY B N     1 
ATOM   3415  C CA    . GLY B 1 15  ? -8.752   -52.871  -9.867  1.00 21.13  ? 15   GLY B CA    1 
ATOM   3416  C C     . GLY B 1 15  ? -10.073  -52.900  -10.644 1.00 23.69  ? 15   GLY B C     1 
ATOM   3417  O O     . GLY B 1 15  ? -10.637  -53.977  -10.908 1.00 22.54  ? 15   GLY B O     1 
ATOM   3418  N N     . LEU B 1 16  ? -10.567  -51.706  -10.974 1.00 18.17  ? 16   LEU B N     1 
ATOM   3419  C CA    . LEU B 1 16  ? -11.903  -51.520  -11.491 1.00 19.47  ? 16   LEU B CA    1 
ATOM   3420  C C     . LEU B 1 16  ? -11.818  -50.703  -12.779 1.00 19.34  ? 16   LEU B C     1 
ATOM   3421  O O     . LEU B 1 16  ? -11.174  -49.643  -12.826 1.00 21.44  ? 16   LEU B O     1 
ATOM   3422  C CB    . LEU B 1 16  ? -12.757  -50.808  -10.434 1.00 19.02  ? 16   LEU B CB    1 
ATOM   3423  C CG    . LEU B 1 16  ? -14.096  -50.234  -10.924 1.00 21.95  ? 16   LEU B CG    1 
ATOM   3424  C CD1   . LEU B 1 16  ? -15.103  -51.311  -11.327 1.00 19.54  ? 16   LEU B CD1   1 
ATOM   3425  C CD2   . LEU B 1 16  ? -14.694  -49.295  -9.879  1.00 20.98  ? 16   LEU B CD2   1 
ATOM   3426  N N     . GLY B 1 17  ? -12.483  -51.196  -13.820 1.00 18.98  ? 17   GLY B N     1 
ATOM   3427  C CA    . GLY B 1 17  ? -12.617  -50.420  -15.041 1.00 20.45  ? 17   GLY B CA    1 
ATOM   3428  C C     . GLY B 1 17  ? -14.081  -50.298  -15.463 1.00 22.01  ? 17   GLY B C     1 
ATOM   3429  O O     . GLY B 1 17  ? -14.933  -51.104  -15.061 1.00 20.65  ? 17   GLY B O     1 
ATOM   3430  N N     . LEU B 1 18  ? -14.349  -49.308  -16.309 1.00 18.34  ? 18   LEU B N     1 
ATOM   3431  C CA    . LEU B 1 18  ? -15.653  -49.189  -16.915 1.00 19.71  ? 18   LEU B CA    1 
ATOM   3432  C C     . LEU B 1 18  ? -15.579  -49.706  -18.354 1.00 21.47  ? 18   LEU B C     1 
ATOM   3433  O O     . LEU B 1 18  ? -14.692  -49.314  -19.126 1.00 21.85  ? 18   LEU B O     1 
ATOM   3434  C CB    . LEU B 1 18  ? -15.898  -47.686  -16.853 1.00 23.79  ? 18   LEU B CB    1 
ATOM   3435  C CG    . LEU B 1 18  ? -17.322  -47.252  -17.160 1.00 30.00  ? 18   LEU B CG    1 
ATOM   3436  C CD1   . LEU B 1 18  ? -18.158  -47.826  -16.029 1.00 32.20  ? 18   LEU B CD1   1 
ATOM   3437  C CD2   . LEU B 1 18  ? -17.442  -45.741  -17.146 1.00 30.50  ? 18   LEU B CD2   1 
ATOM   3438  N N     . PHE B 1 19  ? -16.512  -50.598  -18.708 1.00 19.81  ? 19   PHE B N     1 
ATOM   3439  C CA    . PHE B 1 19  ? -16.651  -51.108  -20.067 1.00 19.03  ? 19   PHE B CA    1 
ATOM   3440  C C     . PHE B 1 19  ? -17.759  -50.314  -20.745 1.00 21.75  ? 19   PHE B C     1 
ATOM   3441  O O     . PHE B 1 19  ? -18.827  -50.130  -20.145 1.00 22.32  ? 19   PHE B O     1 
ATOM   3442  C CB    . PHE B 1 19  ? -17.111  -52.572  -19.958 1.00 17.88  ? 19   PHE B CB    1 
ATOM   3443  C CG    . PHE B 1 19  ? -16.650  -53.522  -21.058 1.00 19.11  ? 19   PHE B CG    1 
ATOM   3444  C CD1   . PHE B 1 19  ? -16.319  -53.063  -22.338 1.00 18.92  ? 19   PHE B CD1   1 
ATOM   3445  C CD2   . PHE B 1 19  ? -16.597  -54.889  -20.829 1.00 19.71  ? 19   PHE B CD2   1 
ATOM   3446  C CE1   . PHE B 1 19  ? -15.906  -53.933  -23.345 1.00 17.08  ? 19   PHE B CE1   1 
ATOM   3447  C CE2   . PHE B 1 19  ? -16.164  -55.764  -21.832 1.00 20.04  ? 19   PHE B CE2   1 
ATOM   3448  C CZ    . PHE B 1 19  ? -15.828  -55.281  -23.096 1.00 17.48  ? 19   PHE B CZ    1 
ATOM   3449  N N     . ILE B 1 20  ? -17.514  -49.846  -21.985 1.00 20.35  ? 20   ILE B N     1 
ATOM   3450  C CA    . ILE B 1 20  ? -18.508  -49.045  -22.695 1.00 20.96  ? 20   ILE B CA    1 
ATOM   3451  C C     . ILE B 1 20  ? -18.809  -49.637  -24.069 1.00 23.48  ? 20   ILE B C     1 
ATOM   3452  O O     . ILE B 1 20  ? -17.912  -49.718  -24.913 1.00 23.83  ? 20   ILE B O     1 
ATOM   3453  C CB    . ILE B 1 20  ? -18.045  -47.586  -22.796 1.00 19.56  ? 20   ILE B CB    1 
ATOM   3454  C CG1   . ILE B 1 20  ? -17.898  -47.020  -21.371 1.00 22.53  ? 20   ILE B CG1   1 
ATOM   3455  C CG2   . ILE B 1 20  ? -19.061  -46.771  -23.619 1.00 18.28  ? 20   ILE B CG2   1 
ATOM   3456  C CD1   . ILE B 1 20  ? -17.514  -45.572  -21.298 1.00 24.57  ? 20   ILE B CD1   1 
ATOM   3457  N N     . HIS B 1 21  ? -20.078  -50.036  -24.274 1.00 23.18  ? 21   HIS B N     1 
ATOM   3458  C CA    . HIS B 1 21  ? -20.550  -50.561  -25.550 1.00 19.55  ? 21   HIS B CA    1 
ATOM   3459  C C     . HIS B 1 21  ? -21.358  -49.477  -26.246 1.00 18.28  ? 21   HIS B C     1 
ATOM   3460  O O     . HIS B 1 21  ? -22.381  -49.013  -25.738 1.00 19.64  ? 21   HIS B O     1 
ATOM   3461  C CB    . HIS B 1 21  ? -21.429  -51.791  -25.358 1.00 17.76  ? 21   HIS B CB    1 
ATOM   3462  C CG    . HIS B 1 21  ? -20.638  -53.031  -25.176 1.00 19.26  ? 21   HIS B CG    1 
ATOM   3463  N ND1   . HIS B 1 21  ? -19.926  -53.286  -24.018 1.00 18.34  ? 21   HIS B ND1   1 
ATOM   3464  C CD2   . HIS B 1 21  ? -20.398  -54.071  -26.029 1.00 17.71  ? 21   HIS B CD2   1 
ATOM   3465  C CE1   . HIS B 1 21  ? -19.285  -54.457  -24.170 1.00 19.72  ? 21   HIS B CE1   1 
ATOM   3466  N NE2   . HIS B 1 21  ? -19.559  -54.949  -25.377 1.00 17.30  ? 21   HIS B NE2   1 
ATOM   3467  N N     . TRP B 1 22  ? -20.867  -49.085  -27.416 1.00 17.18  ? 22   TRP B N     1 
ATOM   3468  C CA    . TRP B 1 22  ? -21.554  -48.095  -28.219 1.00 18.12  ? 22   TRP B CA    1 
ATOM   3469  C C     . TRP B 1 22  ? -21.216  -48.355  -29.679 1.00 18.78  ? 22   TRP B C     1 
ATOM   3470  O O     . TRP B 1 22  ? -20.035  -48.448  -30.027 1.00 17.11  ? 22   TRP B O     1 
ATOM   3471  C CB    . TRP B 1 22  ? -21.060  -46.708  -27.797 1.00 17.51  ? 22   TRP B CB    1 
ATOM   3472  C CG    . TRP B 1 22  ? -21.752  -45.588  -28.516 1.00 17.75  ? 22   TRP B CG    1 
ATOM   3473  C CD1   . TRP B 1 22  ? -23.062  -45.503  -28.916 1.00 18.21  ? 22   TRP B CD1   1 
ATOM   3474  C CD2   . TRP B 1 22  ? -21.135  -44.350  -28.904 1.00 17.42  ? 22   TRP B CD2   1 
ATOM   3475  N NE1   . TRP B 1 22  ? -23.307  -44.291  -29.520 1.00 16.46  ? 22   TRP B NE1   1 
ATOM   3476  C CE2   . TRP B 1 22  ? -22.130  -43.575  -29.540 1.00 17.97  ? 22   TRP B CE2   1 
ATOM   3477  C CE3   . TRP B 1 22  ? -19.831  -43.846  -28.802 1.00 18.66  ? 22   TRP B CE3   1 
ATOM   3478  C CZ2   . TRP B 1 22  ? -21.853  -42.307  -30.063 1.00 20.00  ? 22   TRP B CZ2   1 
ATOM   3479  C CZ3   . TRP B 1 22  ? -19.558  -42.592  -29.307 1.00 20.17  ? 22   TRP B CZ3   1 
ATOM   3480  C CH2   . TRP B 1 22  ? -20.566  -41.835  -29.930 1.00 21.18  ? 22   TRP B CH2   1 
ATOM   3481  N N     . GLY B 1 23  ? -22.251  -48.485  -30.508 1.00 18.57  ? 23   GLY B N     1 
ATOM   3482  C CA    . GLY B 1 23  ? -22.068  -48.699  -31.936 1.00 21.99  ? 23   GLY B CA    1 
ATOM   3483  C C     . GLY B 1 23  ? -23.357  -48.345  -32.672 1.00 23.36  ? 23   GLY B C     1 
ATOM   3484  O O     . GLY B 1 23  ? -24.245  -47.711  -32.084 1.00 21.75  ? 23   GLY B O     1 
ATOM   3485  N N     . LEU B 1 24  ? -23.475  -48.784  -33.935 1.00 19.40  ? 24   LEU B N     1 
ATOM   3486  C CA    . LEU B 1 24  ? -24.689  -48.488  -34.676 1.00 19.41  ? 24   LEU B CA    1 
ATOM   3487  C C     . LEU B 1 24  ? -25.870  -49.178  -33.981 1.00 18.41  ? 24   LEU B C     1 
ATOM   3488  O O     . LEU B 1 24  ? -26.967  -48.618  -33.957 1.00 19.93  ? 24   LEU B O     1 
ATOM   3489  C CB    . LEU B 1 24  ? -24.588  -48.896  -36.149 1.00 20.58  ? 24   LEU B CB    1 
ATOM   3490  C CG    . LEU B 1 24  ? -23.451  -48.236  -36.943 1.00 22.91  ? 24   LEU B CG    1 
ATOM   3491  C CD1   . LEU B 1 24  ? -23.431  -48.734  -38.380 1.00 20.11  ? 24   LEU B CD1   1 
ATOM   3492  C CD2   . LEU B 1 24  ? -23.493  -46.717  -36.920 1.00 16.79  ? 24   LEU B CD2   1 
ATOM   3493  N N     . TYR B 1 25  ? -25.618  -50.363  -33.396 1.00 16.88  ? 25   TYR B N     1 
ATOM   3494  C CA    . TYR B 1 25  ? -26.655  -51.147  -32.741 1.00 18.85  ? 25   TYR B CA    1 
ATOM   3495  C C     . TYR B 1 25  ? -27.372  -50.299  -31.679 1.00 21.63  ? 25   TYR B C     1 
ATOM   3496  O O     . TYR B 1 25  ? -28.541  -50.520  -31.406 1.00 22.33  ? 25   TYR B O     1 
ATOM   3497  C CB    . TYR B 1 25  ? -26.121  -52.405  -32.044 1.00 17.64  ? 25   TYR B CB    1 
ATOM   3498  C CG    . TYR B 1 25  ? -24.806  -52.183  -31.297 1.00 21.77  ? 25   TYR B CG    1 
ATOM   3499  C CD1   . TYR B 1 25  ? -24.783  -51.692  -29.989 1.00 20.07  ? 25   TYR B CD1   1 
ATOM   3500  C CD2   . TYR B 1 25  ? -23.580  -52.494  -31.900 1.00 19.30  ? 25   TYR B CD2   1 
ATOM   3501  C CE1   . TYR B 1 25  ? -23.581  -51.497  -29.312 1.00 21.47  ? 25   TYR B CE1   1 
ATOM   3502  C CE2   . TYR B 1 25  ? -22.385  -52.296  -31.238 1.00 20.28  ? 25   TYR B CE2   1 
ATOM   3503  C CZ    . TYR B 1 25  ? -22.377  -51.792  -29.936 1.00 24.59  ? 25   TYR B CZ    1 
ATOM   3504  O OH    . TYR B 1 25  ? -21.168  -51.570  -29.303 1.00 21.50  ? 25   TYR B OH    1 
ATOM   3505  N N     . SER B 1 26  ? -26.662  -49.348  -31.062 1.00 18.59  ? 26   SER B N     1 
ATOM   3506  C CA    . SER B 1 26  ? -27.221  -48.586  -29.961 1.00 19.54  ? 26   SER B CA    1 
ATOM   3507  C C     . SER B 1 26  ? -28.476  -47.825  -30.391 1.00 21.87  ? 26   SER B C     1 
ATOM   3508  O O     . SER B 1 26  ? -29.379  -47.562  -29.591 1.00 20.86  ? 26   SER B O     1 
ATOM   3509  C CB    . SER B 1 26  ? -26.185  -47.617  -29.397 1.00 22.97  ? 26   SER B CB    1 
ATOM   3510  O OG    . SER B 1 26  ? -25.008  -48.324  -29.020 1.00 20.61  ? 26   SER B OG    1 
ATOM   3511  N N     . GLN B 1 27  ? -28.554  -47.464  -31.675 1.00 22.19  ? 27   GLN B N     1 
ATOM   3512  C CA    . GLN B 1 27  ? -29.729  -46.737  -32.125 1.00 22.16  ? 27   GLN B CA    1 
ATOM   3513  C C     . GLN B 1 27  ? -30.995  -47.589  -32.050 1.00 23.12  ? 27   GLN B C     1 
ATOM   3514  O O     . GLN B 1 27  ? -32.071  -47.044  -31.982 1.00 23.66  ? 27   GLN B O     1 
ATOM   3515  C CB    . GLN B 1 27  ? -29.593  -46.174  -33.529 1.00 22.29  ? 27   GLN B CB    1 
ATOM   3516  C CG    . GLN B 1 27  ? -28.688  -44.952  -33.572 1.00 20.93  ? 27   GLN B CG    1 
ATOM   3517  C CD    . GLN B 1 27  ? -28.309  -44.619  -34.987 1.00 23.85  ? 27   GLN B CD    1 
ATOM   3518  O OE1   . GLN B 1 27  ? -27.177  -44.862  -35.417 1.00 27.71  ? 27   GLN B OE1   1 
ATOM   3519  N NE2   . GLN B 1 27  ? -29.286  -44.165  -35.748 1.00 20.91  ? 27   GLN B NE2   1 
ATOM   3520  N N     . MET B 1 28  ? -30.892  -48.920  -32.065 1.00 21.89  ? 28   MET B N     1 
ATOM   3521  C CA    . MET B 1 28  ? -32.083  -49.750  -32.038 1.00 24.74  ? 28   MET B CA    1 
ATOM   3522  C C     . MET B 1 28  ? -32.455  -50.194  -30.632 1.00 26.33  ? 28   MET B C     1 
ATOM   3523  O O     . MET B 1 28  ? -33.583  -50.619  -30.427 1.00 24.38  ? 28   MET B O     1 
ATOM   3524  C CB    . MET B 1 28  ? -31.815  -51.005  -32.854 1.00 27.32  ? 28   MET B CB    1 
ATOM   3525  C CG    . MET B 1 28  ? -31.724  -50.512  -34.285 1.00 36.13  ? 28   MET B CG    1 
ATOM   3526  S SD    . MET B 1 28  ? -31.703  -51.848  -35.472 1.00 59.99  ? 28   MET B SD    1 
ATOM   3527  C CE    . MET B 1 28  ? -32.814  -50.839  -36.475 1.00 68.19  ? 28   MET B CE    1 
ATOM   3528  N N     . ALA B 1 29  ? -31.472  -50.223  -29.717 1.00 21.95  ? 29   ALA B N     1 
ATOM   3529  C CA    . ALA B 1 29  ? -31.727  -50.484  -28.309 1.00 21.43  ? 29   ALA B CA    1 
ATOM   3530  C C     . ALA B 1 29  ? -32.353  -51.870  -28.118 1.00 20.29  ? 29   ALA B C     1 
ATOM   3531  O O     . ALA B 1 29  ? -33.241  -52.062  -27.259 1.00 19.35  ? 29   ALA B O     1 
ATOM   3532  C CB    . ALA B 1 29  ? -32.605  -49.360  -27.703 1.00 20.69  ? 29   ALA B CB    1 
ATOM   3533  N N     . VAL B 1 30  ? -31.878  -52.837  -28.912 1.00 19.57  ? 30   VAL B N     1 
ATOM   3534  C CA    . VAL B 1 30  ? -32.314  -54.216  -28.752 1.00 18.94  ? 30   VAL B CA    1 
ATOM   3535  C C     . VAL B 1 30  ? -31.084  -55.117  -28.709 1.00 20.95  ? 30   VAL B C     1 
ATOM   3536  O O     . VAL B 1 30  ? -31.140  -56.230  -29.234 1.00 21.95  ? 30   VAL B O     1 
ATOM   3537  C CB    . VAL B 1 30  ? -33.352  -54.662  -29.821 1.00 22.44  ? 30   VAL B CB    1 
ATOM   3538  C CG1   . VAL B 1 30  ? -34.746  -54.037  -29.572 1.00 17.65  ? 30   VAL B CG1   1 
ATOM   3539  C CG2   . VAL B 1 30  ? -32.881  -54.439  -31.275 1.00 15.20  ? 30   VAL B CG2   1 
ATOM   3540  N N     . GLY B 1 31  ? -29.970  -54.649  -28.084 1.00 21.33  ? 31   GLY B N     1 
ATOM   3541  C CA    . GLY B 1 31  ? -28.796  -55.499  -27.908 1.00 19.52  ? 31   GLY B CA    1 
ATOM   3542  C C     . GLY B 1 31  ? -27.776  -55.364  -29.048 1.00 21.43  ? 31   GLY B C     1 
ATOM   3543  O O     . GLY B 1 31  ? -28.136  -55.037  -30.194 1.00 23.70  ? 31   GLY B O     1 
ATOM   3544  N N     . GLU B 1 32  ? -26.486  -55.575  -28.726 1.00 17.97  ? 32   GLU B N     1 
ATOM   3545  C CA    . GLU B 1 32  ? -25.414  -55.311  -29.677 1.00 17.83  ? 32   GLU B CA    1 
ATOM   3546  C C     . GLU B 1 32  ? -25.338  -56.395  -30.776 1.00 20.10  ? 32   GLU B C     1 
ATOM   3547  O O     . GLU B 1 32  ? -24.772  -56.132  -31.840 1.00 19.32  ? 32   GLU B O     1 
ATOM   3548  C CB    . GLU B 1 32  ? -24.077  -55.104  -28.967 1.00 15.38  ? 32   GLU B CB    1 
ATOM   3549  C CG    . GLU B 1 32  ? -23.498  -56.349  -28.306 1.00 17.59  ? 32   GLU B CG    1 
ATOM   3550  C CD    . GLU B 1 32  ? -24.183  -56.922  -27.056 1.00 21.46  ? 32   GLU B CD    1 
ATOM   3551  O OE1   . GLU B 1 32  ? -25.178  -56.374  -26.492 1.00 21.68  ? 32   GLU B OE1   1 
ATOM   3552  O OE2   . GLU B 1 32  ? -23.678  -57.996  -26.612 1.00 21.92  ? 32   GLU B OE2   1 
ATOM   3553  N N     . TRP B 1 33  ? -25.888  -57.595  -30.538 1.00 18.43  ? 33   TRP B N     1 
ATOM   3554  C CA    . TRP B 1 33  ? -25.866  -58.638  -31.561 1.00 23.16  ? 33   TRP B CA    1 
ATOM   3555  C C     . TRP B 1 33  ? -27.081  -58.561  -32.499 1.00 24.21  ? 33   TRP B C     1 
ATOM   3556  O O     . TRP B 1 33  ? -27.331  -59.523  -33.219 1.00 21.79  ? 33   TRP B O     1 
ATOM   3557  C CB    . TRP B 1 33  ? -25.839  -60.024  -30.898 1.00 21.46  ? 33   TRP B CB    1 
ATOM   3558  C CG    . TRP B 1 33  ? -24.473  -60.495  -30.462 1.00 26.85  ? 33   TRP B CG    1 
ATOM   3559  C CD1   . TRP B 1 33  ? -23.704  -59.968  -29.456 1.00 27.86  ? 33   TRP B CD1   1 
ATOM   3560  C CD2   . TRP B 1 33  ? -23.738  -61.628  -30.980 1.00 27.14  ? 33   TRP B CD2   1 
ATOM   3561  N NE1   . TRP B 1 33  ? -22.533  -60.675  -29.340 1.00 26.00  ? 33   TRP B NE1   1 
ATOM   3562  C CE2   . TRP B 1 33  ? -22.526  -61.704  -30.249 1.00 29.21  ? 33   TRP B CE2   1 
ATOM   3563  C CE3   . TRP B 1 33  ? -23.998  -62.604  -31.959 1.00 29.07  ? 33   TRP B CE3   1 
ATOM   3564  C CZ2   . TRP B 1 33  ? -21.568  -62.703  -30.485 1.00 27.85  ? 33   TRP B CZ2   1 
ATOM   3565  C CZ3   . TRP B 1 33  ? -23.049  -63.594  -32.192 1.00 27.35  ? 33   TRP B CZ3   1 
ATOM   3566  C CH2   . TRP B 1 33  ? -21.840  -63.629  -31.478 1.00 28.25  ? 33   TRP B CH2   1 
ATOM   3567  N N     . THR B 1 34  ? -27.829  -57.444  -32.512 1.00 24.44  ? 34   THR B N     1 
ATOM   3568  C CA    . THR B 1 34  ? -29.119  -57.415  -33.195 1.00 23.49  ? 34   THR B CA    1 
ATOM   3569  C C     . THR B 1 34  ? -29.002  -57.809  -34.684 1.00 24.55  ? 34   THR B C     1 
ATOM   3570  O O     . THR B 1 34  ? -29.848  -58.525  -35.223 1.00 22.60  ? 34   THR B O     1 
ATOM   3571  C CB    . THR B 1 34  ? -29.810  -56.060  -32.993 1.00 22.79  ? 34   THR B CB    1 
ATOM   3572  O OG1   . THR B 1 34  ? -31.045  -56.168  -33.694 1.00 22.21  ? 34   THR B OG1   1 
ATOM   3573  C CG2   . THR B 1 34  ? -29.052  -54.889  -33.586 1.00 20.61  ? 34   THR B CG2   1 
ATOM   3574  N N     . GLU B 1 35  ? -27.939  -57.370  -35.363 1.00 24.04  ? 35   GLU B N     1 
ATOM   3575  C CA    . GLU B 1 35  ? -27.808  -57.616  -36.788 1.00 24.48  ? 35   GLU B CA    1 
ATOM   3576  C C     . GLU B 1 35  ? -27.830  -59.110  -37.094 1.00 26.39  ? 35   GLU B C     1 
ATOM   3577  O O     . GLU B 1 35  ? -28.557  -59.543  -37.993 1.00 27.44  ? 35   GLU B O     1 
ATOM   3578  C CB    . GLU B 1 35  ? -26.617  -56.899  -37.416 1.00 24.82  ? 35   GLU B CB    1 
ATOM   3579  C CG    . GLU B 1 35  ? -26.552  -57.156  -38.920 1.00 22.40  ? 35   GLU B CG    1 
ATOM   3580  C CD    . GLU B 1 35  ? -25.348  -56.505  -39.580 1.00 28.18  ? 35   GLU B CD    1 
ATOM   3581  O OE1   . GLU B 1 35  ? -24.340  -56.200  -38.940 1.00 28.55  ? 35   GLU B OE1   1 
ATOM   3582  O OE2   . GLU B 1 35  ? -25.442  -56.243  -40.770 1.00 33.06  ? 35   GLU B OE2   1 
ATOM   3583  N N     . LEU B 1 36  ? -27.058  -59.897  -36.345 1.00 24.06  ? 36   LEU B N     1 
ATOM   3584  C CA    . LEU B 1 36  ? -27.029  -61.337  -36.572 1.00 25.39  ? 36   LEU B CA    1 
ATOM   3585  C C     . LEU B 1 36  ? -28.275  -62.001  -35.982 1.00 26.89  ? 36   LEU B C     1 
ATOM   3586  O O     . LEU B 1 36  ? -28.965  -62.733  -36.674 1.00 29.31  ? 36   LEU B O     1 
ATOM   3587  C CB    . LEU B 1 36  ? -25.744  -61.969  -36.045 1.00 26.07  ? 36   LEU B CB    1 
ATOM   3588  C CG    . LEU B 1 36  ? -25.582  -63.468  -36.349 1.00 31.60  ? 36   LEU B CG    1 
ATOM   3589  C CD1   . LEU B 1 36  ? -24.143  -63.853  -36.550 1.00 28.54  ? 36   LEU B CD1   1 
ATOM   3590  C CD2   . LEU B 1 36  ? -26.152  -64.399  -35.284 1.00 34.66  ? 36   LEU B CD2   1 
ATOM   3591  N N     . ILE B 1 37  ? -28.562  -61.817  -34.712 1.00 24.78  ? 37   ILE B N     1 
ATOM   3592  C CA    . ILE B 1 37  ? -29.644  -62.500  -34.022 1.00 22.41  ? 37   ILE B CA    1 
ATOM   3593  C C     . ILE B 1 37  ? -31.056  -62.260  -34.511 1.00 21.73  ? 37   ILE B C     1 
ATOM   3594  O O     . ILE B 1 37  ? -31.862  -63.119  -34.469 1.00 20.01  ? 37   ILE B O     1 
ATOM   3595  C CB    . ILE B 1 37  ? -29.510  -62.375  -32.490 1.00 23.76  ? 37   ILE B CB    1 
ATOM   3596  C CG1   . ILE B 1 37  ? -28.180  -62.930  -32.041 1.00 25.94  ? 37   ILE B CG1   1 
ATOM   3597  C CG2   . ILE B 1 37  ? -30.598  -63.117  -31.777 1.00 18.66  ? 37   ILE B CG2   1 
ATOM   3598  C CD1   . ILE B 1 37  ? -27.955  -62.825  -30.563 1.00 26.64  ? 37   ILE B CD1   1 
ATOM   3599  N N     . HIS B 1 38  ? -31.333  -61.063  -34.975 1.00 21.14  ? 38   HIS B N     1 
ATOM   3600  C CA    . HIS B 1 38  ? -32.614  -60.692  -35.510 1.00 19.90  ? 38   HIS B CA    1 
ATOM   3601  C C     . HIS B 1 38  ? -32.694  -60.888  -37.000 1.00 21.65  ? 38   HIS B C     1 
ATOM   3602  O O     . HIS B 1 38  ? -33.606  -60.450  -37.598 1.00 23.06  ? 38   HIS B O     1 
ATOM   3603  C CB    . HIS B 1 38  ? -33.001  -59.274  -35.142 1.00 18.74  ? 38   HIS B CB    1 
ATOM   3604  C CG    . HIS B 1 38  ? -33.290  -59.101  -33.701 1.00 22.65  ? 38   HIS B CG    1 
ATOM   3605  N ND1   . HIS B 1 38  ? -32.701  -58.130  -32.938 1.00 23.40  ? 38   HIS B ND1   1 
ATOM   3606  C CD2   . HIS B 1 38  ? -34.066  -59.812  -32.867 1.00 21.85  ? 38   HIS B CD2   1 
ATOM   3607  C CE1   . HIS B 1 38  ? -33.130  -58.236  -31.705 1.00 24.24  ? 38   HIS B CE1   1 
ATOM   3608  N NE2   . HIS B 1 38  ? -33.950  -59.255  -31.636 1.00 21.41  ? 38   HIS B NE2   1 
ATOM   3609  N N     . HIS B 1 39  ? -31.669  -61.473  -37.579 1.00 27.32  ? 39   HIS B N     1 
ATOM   3610  C CA    . HIS B 1 39  ? -31.581  -61.834  -38.974 1.00 33.64  ? 39   HIS B CA    1 
ATOM   3611  C C     . HIS B 1 39  ? -31.873  -60.670  -39.919 1.00 32.79  ? 39   HIS B C     1 
ATOM   3612  O O     . HIS B 1 39  ? -32.683  -60.753  -40.784 1.00 29.15  ? 39   HIS B O     1 
ATOM   3613  C CB    . HIS B 1 39  ? -32.391  -63.120  -39.255 1.00 41.45  ? 39   HIS B CB    1 
ATOM   3614  C CG    . HIS B 1 39  ? -31.856  -63.954  -40.393 1.00 79.83  ? 39   HIS B CG    1 
ATOM   3615  N ND1   . HIS B 1 39  ? -32.661  -64.467  -41.395 1.00 101.99 ? 39   HIS B ND1   1 
ATOM   3616  C CD2   . HIS B 1 39  ? -30.595  -64.337  -40.709 1.00 96.08  ? 39   HIS B CD2   1 
ATOM   3617  C CE1   . HIS B 1 39  ? -31.925  -65.140  -42.258 1.00 99.65  ? 39   HIS B CE1   1 
ATOM   3618  N NE2   . HIS B 1 39  ? -30.667  -65.075  -41.867 1.00 104.14 ? 39   HIS B NE2   1 
ATOM   3619  N N     . ARG B 1 40  ? -31.241  -59.553  -39.668 1.00 29.19  ? 40   ARG B N     1 
ATOM   3620  C CA    . ARG B 1 40  ? -31.420  -58.371  -40.455 1.00 26.21  ? 40   ARG B CA    1 
ATOM   3621  C C     . ARG B 1 40  ? -30.724  -58.355  -41.798 1.00 27.51  ? 40   ARG B C     1 
ATOM   3622  O O     . ARG B 1 40  ? -29.711  -58.948  -41.967 1.00 24.28  ? 40   ARG B O     1 
ATOM   3623  C CB    . ARG B 1 40  ? -30.996  -57.163  -39.645 1.00 24.11  ? 40   ARG B CB    1 
ATOM   3624  C CG    . ARG B 1 40  ? -31.752  -56.955  -38.357 1.00 25.18  ? 40   ARG B CG    1 
ATOM   3625  C CD    . ARG B 1 40  ? -31.391  -55.632  -37.716 1.00 26.46  ? 40   ARG B CD    1 
ATOM   3626  N NE    . ARG B 1 40  ? -31.944  -55.481  -36.391 1.00 32.48  ? 40   ARG B NE    1 
ATOM   3627  C CZ    . ARG B 1 40  ? -33.137  -54.989  -36.092 1.00 37.38  ? 40   ARG B CZ    1 
ATOM   3628  N NH1   . ARG B 1 40  ? -33.958  -54.566  -37.012 1.00 33.37  ? 40   ARG B NH1   1 
ATOM   3629  N NH2   . ARG B 1 40  ? -33.510  -54.915  -34.852 1.00 32.35  ? 40   ARG B NH2   1 
ATOM   3630  N N     . ASN B 1 41  ? -31.319  -57.690  -42.760 1.00 22.85  ? 41   ASN B N     1 
ATOM   3631  C CA    . ASN B 1 41  ? -30.704  -57.499  -44.020 1.00 18.97  ? 41   ASN B CA    1 
ATOM   3632  C C     . ASN B 1 41  ? -29.570  -56.532  -43.715 1.00 22.03  ? 41   ASN B C     1 
ATOM   3633  O O     . ASN B 1 41  ? -29.764  -55.545  -43.095 1.00 24.47  ? 41   ASN B O     1 
ATOM   3634  C CB    . ASN B 1 41  ? -31.712  -56.929  -45.002 1.00 18.66  ? 41   ASN B CB    1 
ATOM   3635  C CG    . ASN B 1 41  ? -31.091  -56.456  -46.285 1.00 21.11  ? 41   ASN B CG    1 
ATOM   3636  O OD1   . ASN B 1 41  ? -30.721  -55.342  -46.408 1.00 22.06  ? 41   ASN B OD1   1 
ATOM   3637  N ND2   . ASN B 1 41  ? -31.011  -57.312  -47.233 1.00 18.01  ? 41   ASN B ND2   1 
ATOM   3638  N N     . GLN B 1 42  ? -28.380  -56.853  -44.153 1.00 23.01  ? 42   GLN B N     1 
ATOM   3639  C CA    . GLN B 1 42  ? -27.187  -56.069  -43.898 1.00 22.53  ? 42   GLN B CA    1 
ATOM   3640  C C     . GLN B 1 42  ? -27.303  -54.629  -44.394 1.00 22.58  ? 42   GLN B C     1 
ATOM   3641  O O     . GLN B 1 42  ? -26.967  -53.693  -43.688 1.00 22.71  ? 42   GLN B O     1 
ATOM   3642  C CB    . GLN B 1 42  ? -25.939  -56.792  -44.395 1.00 25.17  ? 42   GLN B CB    1 
ATOM   3643  C CG    . GLN B 1 42  ? -24.679  -55.970  -44.134 1.00 25.00  ? 42   GLN B CG    1 
ATOM   3644  C CD    . GLN B 1 42  ? -23.418  -56.792  -44.163 1.00 32.91  ? 42   GLN B CD    1 
ATOM   3645  O OE1   . GLN B 1 42  ? -22.845  -57.049  -45.223 1.00 40.07  ? 42   GLN B OE1   1 
ATOM   3646  N NE2   . GLN B 1 42  ? -22.894  -57.055  -42.962 1.00 29.08  ? 42   GLN B NE2   1 
ATOM   3647  N N     . HIS B 1 43  ? -27.748  -54.444  -45.632 1.00 22.59  ? 43   HIS B N     1 
ATOM   3648  C CA    . HIS B 1 43  ? -27.827  -53.115  -46.223 1.00 21.00  ? 43   HIS B CA    1 
ATOM   3649  C C     . HIS B 1 43  ? -28.758  -52.240  -45.367 1.00 22.52  ? 43   HIS B C     1 
ATOM   3650  O O     . HIS B 1 43  ? -28.462  -51.076  -45.166 1.00 21.82  ? 43   HIS B O     1 
ATOM   3651  C CB    . HIS B 1 43  ? -28.254  -53.192  -47.704 1.00 21.15  ? 43   HIS B CB    1 
ATOM   3652  C CG    . HIS B 1 43  ? -28.631  -51.857  -48.270 1.00 24.70  ? 43   HIS B CG    1 
ATOM   3653  N ND1   . HIS B 1 43  ? -29.917  -51.325  -48.207 1.00 24.75  ? 43   HIS B ND1   1 
ATOM   3654  C CD2   . HIS B 1 43  ? -27.845  -50.880  -48.820 1.00 27.98  ? 43   HIS B CD2   1 
ATOM   3655  C CE1   . HIS B 1 43  ? -29.909  -50.073  -48.718 1.00 26.19  ? 43   HIS B CE1   1 
ATOM   3656  N NE2   . HIS B 1 43  ? -28.672  -49.784  -49.102 1.00 25.18  ? 43   HIS B NE2   1 
ATOM   3657  N N     . ASP B 1 44  ? -29.893  -52.784  -44.899 1.00 22.03  ? 44   ASP B N     1 
ATOM   3658  C CA    . ASP B 1 44  ? -30.872  -51.998  -44.163 1.00 25.23  ? 44   ASP B CA    1 
ATOM   3659  C C     . ASP B 1 44  ? -30.310  -51.596  -42.798 1.00 27.20  ? 44   ASP B C     1 
ATOM   3660  O O     . ASP B 1 44  ? -30.373  -50.406  -42.443 1.00 25.52  ? 44   ASP B O     1 
ATOM   3661  C CB    . ASP B 1 44  ? -32.215  -52.700  -44.071 1.00 27.94  ? 44   ASP B CB    1 
ATOM   3662  C CG    . ASP B 1 44  ? -32.906  -52.959  -45.415 1.00 33.63  ? 44   ASP B CG    1 
ATOM   3663  O OD1   . ASP B 1 44  ? -32.554  -52.276  -46.404 1.00 31.40  ? 44   ASP B OD1   1 
ATOM   3664  O OD2   . ASP B 1 44  ? -33.782  -53.849  -45.485 1.00 38.97  ? 44   ASP B OD2   1 
ATOM   3665  N N     . TYR B 1 45  ? -29.678  -52.569  -42.106 1.00 21.90  ? 45   TYR B N     1 
ATOM   3666  C CA    . TYR B 1 45  ? -29.038  -52.296  -40.840 1.00 21.19  ? 45   TYR B CA    1 
ATOM   3667  C C     . TYR B 1 45  ? -27.961  -51.211  -40.976 1.00 22.90  ? 45   TYR B C     1 
ATOM   3668  O O     . TYR B 1 45  ? -27.922  -50.257  -40.180 1.00 24.09  ? 45   TYR B O     1 
ATOM   3669  C CB    . TYR B 1 45  ? -28.537  -53.623  -40.264 1.00 23.22  ? 45   TYR B CB    1 
ATOM   3670  C CG    . TYR B 1 45  ? -27.794  -53.427  -38.949 1.00 24.27  ? 45   TYR B CG    1 
ATOM   3671  C CD1   . TYR B 1 45  ? -28.463  -53.286  -37.725 1.00 22.47  ? 45   TYR B CD1   1 
ATOM   3672  C CD2   . TYR B 1 45  ? -26.410  -53.327  -38.942 1.00 26.63  ? 45   TYR B CD2   1 
ATOM   3673  C CE1   . TYR B 1 45  ? -27.767  -53.098  -36.549 1.00 21.64  ? 45   TYR B CE1   1 
ATOM   3674  C CE2   . TYR B 1 45  ? -25.704  -53.176  -37.756 1.00 26.91  ? 45   TYR B CE2   1 
ATOM   3675  C CZ    . TYR B 1 45  ? -26.390  -53.064  -36.564 1.00 23.41  ? 45   TYR B CZ    1 
ATOM   3676  O OH    . TYR B 1 45  ? -25.686  -52.941  -35.412 1.00 22.32  ? 45   TYR B OH    1 
ATOM   3677  N N     . GLU B 1 46  ? -27.108  -51.335  -42.000 1.00 24.26  ? 46   GLU B N     1 
ATOM   3678  C CA    . GLU B 1 46  ? -25.952  -50.457  -42.158 1.00 24.39  ? 46   GLU B CA    1 
ATOM   3679  C C     . GLU B 1 46  ? -26.354  -49.032  -42.499 1.00 24.05  ? 46   GLU B C     1 
ATOM   3680  O O     . GLU B 1 46  ? -25.520  -48.145  -42.384 1.00 28.33  ? 46   GLU B O     1 
ATOM   3681  C CB    . GLU B 1 46  ? -24.877  -51.050  -43.066 1.00 24.06  ? 46   GLU B CB    1 
ATOM   3682  C CG    . GLU B 1 46  ? -24.319  -52.342  -42.464 1.00 30.59  ? 46   GLU B CG    1 
ATOM   3683  C CD    . GLU B 1 46  ? -23.067  -52.836  -43.195 1.00 30.55  ? 46   GLU B CD    1 
ATOM   3684  O OE1   . GLU B 1 46  ? -22.801  -52.313  -44.315 1.00 36.24  ? 46   GLU B OE1   1 
ATOM   3685  O OE2   . GLU B 1 46  ? -22.360  -53.727  -42.626 1.00 32.21  ? 46   GLU B OE2   1 
ATOM   3686  N N     . GLN B 1 47  ? -27.626  -48.800  -42.869 1.00 24.19  ? 47   GLN B N     1 
ATOM   3687  C CA    . GLN B 1 47  ? -28.121  -47.439  -43.060 1.00 26.64  ? 47   GLN B CA    1 
ATOM   3688  C C     . GLN B 1 47  ? -28.056  -46.605  -41.771 1.00 26.30  ? 47   GLN B C     1 
ATOM   3689  O O     . GLN B 1 47  ? -28.104  -45.368  -41.831 1.00 27.65  ? 47   GLN B O     1 
ATOM   3690  C CB    . GLN B 1 47  ? -29.564  -47.444  -43.572 1.00 27.19  ? 47   GLN B CB    1 
ATOM   3691  C CG    . GLN B 1 47  ? -29.727  -47.963  -45.003 1.00 31.20  ? 47   GLN B CG    1 
ATOM   3692  C CD    . GLN B 1 47  ? -29.001  -47.113  -46.022 1.00 35.99  ? 47   GLN B CD    1 
ATOM   3693  O OE1   . GLN B 1 47  ? -29.377  -45.972  -46.309 1.00 45.04  ? 47   GLN B OE1   1 
ATOM   3694  N NE2   . GLN B 1 47  ? -27.926  -47.659  -46.558 1.00 35.94  ? 47   GLN B NE2   1 
ATOM   3695  N N     . LEU B 1 48  ? -27.964  -47.286  -40.615 1.00 22.17  ? 48   LEU B N     1 
ATOM   3696  C CA    . LEU B 1 48  ? -27.826  -46.618  -39.328 1.00 22.42  ? 48   LEU B CA    1 
ATOM   3697  C C     . LEU B 1 48  ? -26.609  -45.685  -39.309 1.00 22.62  ? 48   LEU B C     1 
ATOM   3698  O O     . LEU B 1 48  ? -26.574  -44.758  -38.498 1.00 21.93  ? 48   LEU B O     1 
ATOM   3699  C CB    . LEU B 1 48  ? -27.780  -47.623  -38.177 1.00 21.62  ? 48   LEU B CB    1 
ATOM   3700  C CG    . LEU B 1 48  ? -29.106  -48.344  -37.894 1.00 22.92  ? 48   LEU B CG    1 
ATOM   3701  C CD1   . LEU B 1 48  ? -28.939  -49.500  -36.916 1.00 18.57  ? 48   LEU B CD1   1 
ATOM   3702  C CD2   . LEU B 1 48  ? -30.200  -47.373  -37.452 1.00 17.57  ? 48   LEU B CD2   1 
ATOM   3703  N N     . ILE B 1 49  ? -25.622  -45.903  -40.200 1.00 21.75  ? 49   ILE B N     1 
ATOM   3704  C CA    . ILE B 1 49  ? -24.495  -44.982  -40.273 1.00 23.65  ? 49   ILE B CA    1 
ATOM   3705  C C     . ILE B 1 49  ? -24.976  -43.552  -40.558 1.00 25.79  ? 49   ILE B C     1 
ATOM   3706  O O     . ILE B 1 49  ? -24.368  -42.574  -40.088 1.00 26.79  ? 49   ILE B O     1 
ATOM   3707  C CB    . ILE B 1 49  ? -23.379  -45.435  -41.232 1.00 26.83  ? 49   ILE B CB    1 
ATOM   3708  C CG1   . ILE B 1 49  ? -22.090  -44.604  -41.006 1.00 22.87  ? 49   ILE B CG1   1 
ATOM   3709  C CG2   . ILE B 1 49  ? -23.823  -45.359  -42.699 1.00 21.00  ? 49   ILE B CG2   1 
ATOM   3710  C CD1   . ILE B 1 49  ? -20.865  -45.153  -41.744 1.00 23.12  ? 49   ILE B CD1   1 
ATOM   3711  N N     . LYS B 1 50  ? -26.080  -43.419  -41.303 1.00 24.81  ? 50   LYS B N     1 
ATOM   3712  C CA    . LYS B 1 50  ? -26.501  -42.094  -41.762 1.00 26.26  ? 50   LYS B CA    1 
ATOM   3713  C C     . LYS B 1 50  ? -27.087  -41.275  -40.621 1.00 26.95  ? 50   LYS B C     1 
ATOM   3714  O O     . LYS B 1 50  ? -27.165  -40.061  -40.743 1.00 26.77  ? 50   LYS B O     1 
ATOM   3715  C CB    . LYS B 1 50  ? -27.520  -42.162  -42.904 1.00 28.86  ? 50   LYS B CB    1 
ATOM   3716  C CG    . LYS B 1 50  ? -26.868  -42.672  -44.161 1.00 34.36  ? 50   LYS B CG    1 
ATOM   3717  C CD    . LYS B 1 50  ? -27.898  -42.991  -45.230 1.00 40.26  ? 50   LYS B CD    1 
ATOM   3718  C CE    . LYS B 1 50  ? -27.108  -43.250  -46.470 1.00 50.08  ? 50   LYS B CE    1 
ATOM   3719  N NZ    . LYS B 1 50  ? -28.046  -43.572  -47.546 1.00 61.27  ? 50   LYS B NZ    1 
ATOM   3720  N N     . THR B 1 51  ? -27.499  -41.933  -39.526 1.00 25.16  ? 51   THR B N     1 
ATOM   3721  C CA    . THR B 1 51  ? -28.079  -41.228  -38.400 1.00 26.51  ? 51   THR B CA    1 
ATOM   3722  C C     . THR B 1 51  ? -27.143  -41.297  -37.189 1.00 27.67  ? 51   THR B C     1 
ATOM   3723  O O     . THR B 1 51  ? -27.550  -40.962  -36.087 1.00 31.70  ? 51   THR B O     1 
ATOM   3724  C CB    . THR B 1 51  ? -29.500  -41.749  -38.115 1.00 29.46  ? 51   THR B CB    1 
ATOM   3725  O OG1   . THR B 1 51  ? -29.409  -43.170  -38.202 1.00 27.86  ? 51   THR B OG1   1 
ATOM   3726  C CG2   . THR B 1 51  ? -30.518  -41.331  -39.172 1.00 21.21  ? 51   THR B CG2   1 
ATOM   3727  N N     . PHE B 1 52  ? -25.889  -41.730  -37.387 1.00 23.34  ? 52   PHE B N     1 
ATOM   3728  C CA    . PHE B 1 52  ? -24.907  -41.761  -36.314 1.00 21.80  ? 52   PHE B CA    1 
ATOM   3729  C C     . PHE B 1 52  ? -24.279  -40.381  -36.144 1.00 22.64  ? 52   PHE B C     1 
ATOM   3730  O O     . PHE B 1 52  ? -23.238  -40.099  -36.733 1.00 25.67  ? 52   PHE B O     1 
ATOM   3731  C CB    . PHE B 1 52  ? -23.839  -42.826  -36.592 1.00 21.30  ? 52   PHE B CB    1 
ATOM   3732  C CG    . PHE B 1 52  ? -22.865  -43.083  -35.444 1.00 22.87  ? 52   PHE B CG    1 
ATOM   3733  C CD1   . PHE B 1 52  ? -23.220  -43.895  -34.363 1.00 23.92  ? 52   PHE B CD1   1 
ATOM   3734  C CD2   . PHE B 1 52  ? -21.596  -42.532  -35.441 1.00 21.45  ? 52   PHE B CD2   1 
ATOM   3735  C CE1   . PHE B 1 52  ? -22.337  -44.134  -33.311 1.00 24.29  ? 52   PHE B CE1   1 
ATOM   3736  C CE2   . PHE B 1 52  ? -20.717  -42.766  -34.376 1.00 24.98  ? 52   PHE B CE2   1 
ATOM   3737  C CZ    . PHE B 1 52  ? -21.083  -43.569  -33.314 1.00 22.71  ? 52   PHE B CZ    1 
ATOM   3738  N N     . THR B 1 53  ? -24.919  -39.522  -35.332 1.00 19.88  ? 53   THR B N     1 
ATOM   3739  C CA    . THR B 1 53  ? -24.502  -38.131  -35.211 1.00 21.32  ? 53   THR B CA    1 
ATOM   3740  C C     . THR B 1 53  ? -23.529  -37.960  -34.046 1.00 24.45  ? 53   THR B C     1 
ATOM   3741  O O     . THR B 1 53  ? -22.823  -36.957  -33.988 1.00 24.70  ? 53   THR B O     1 
ATOM   3742  C CB    . THR B 1 53  ? -25.707  -37.221  -34.976 1.00 24.22  ? 53   THR B CB    1 
ATOM   3743  O OG1   . THR B 1 53  ? -26.218  -37.707  -33.736 1.00 27.64  ? 53   THR B OG1   1 
ATOM   3744  C CG2   . THR B 1 53  ? -26.750  -37.256  -36.079 1.00 21.16  ? 53   THR B CG2   1 
ATOM   3745  N N     . ALA B 1 54  ? -23.555  -38.888  -33.075 1.00 22.57  ? 54   ALA B N     1 
ATOM   3746  C CA    . ALA B 1 54  ? -22.832  -38.749  -31.827 1.00 21.60  ? 54   ALA B CA    1 
ATOM   3747  C C     . ALA B 1 54  ? -23.188  -37.445  -31.139 1.00 25.69  ? 54   ALA B C     1 
ATOM   3748  O O     . ALA B 1 54  ? -22.346  -36.912  -30.418 1.00 27.25  ? 54   ALA B O     1 
ATOM   3749  C CB    . ALA B 1 54  ? -21.342  -38.823  -32.059 1.00 18.50  ? 54   ALA B CB    1 
ATOM   3750  N N     . ALA B 1 55  ? -24.416  -36.948  -31.335 1.00 25.01  ? 55   ALA B N     1 
ATOM   3751  C CA    . ALA B 1 55  ? -24.792  -35.622  -30.849 1.00 28.08  ? 55   ALA B CA    1 
ATOM   3752  C C     . ALA B 1 55  ? -24.678  -35.512  -29.316 1.00 27.30  ? 55   ALA B C     1 
ATOM   3753  O O     . ALA B 1 55  ? -24.586  -34.421  -28.781 1.00 28.64  ? 55   ALA B O     1 
ATOM   3754  C CB    . ALA B 1 55  ? -26.196  -35.245  -31.346 1.00 19.59  ? 55   ALA B CB    1 
ATOM   3755  N N     . GLN B 1 56  ? -24.737  -36.621  -28.583 1.00 27.65  ? 56   GLN B N     1 
ATOM   3756  C CA    . GLN B 1 56  ? -24.708  -36.501  -27.135 1.00 27.95  ? 56   GLN B CA    1 
ATOM   3757  C C     . GLN B 1 56  ? -23.484  -37.189  -26.553 1.00 28.35  ? 56   GLN B C     1 
ATOM   3758  O O     . GLN B 1 56  ? -23.415  -37.407  -25.356 1.00 29.05  ? 56   GLN B O     1 
ATOM   3759  C CB    . GLN B 1 56  ? -25.987  -37.009  -26.488 1.00 29.70  ? 56   GLN B CB    1 
ATOM   3760  C CG    . GLN B 1 56  ? -27.082  -35.959  -26.469 1.00 40.33  ? 56   GLN B CG    1 
ATOM   3761  C CD    . GLN B 1 56  ? -28.399  -36.575  -26.843 1.00 52.14  ? 56   GLN B CD    1 
ATOM   3762  O OE1   . GLN B 1 56  ? -29.124  -37.125  -26.010 1.00 48.19  ? 56   GLN B OE1   1 
ATOM   3763  N NE2   . GLN B 1 56  ? -28.662  -36.554  -28.139 1.00 66.02  ? 56   GLN B NE2   1 
ATOM   3764  N N     . PHE B 1 57  ? -22.506  -37.512  -27.396 1.00 25.29  ? 57   PHE B N     1 
ATOM   3765  C CA    . PHE B 1 57  ? -21.312  -38.139  -26.879 1.00 25.73  ? 57   PHE B CA    1 
ATOM   3766  C C     . PHE B 1 57  ? -20.397  -37.050  -26.349 1.00 29.78  ? 57   PHE B C     1 
ATOM   3767  O O     . PHE B 1 57  ? -19.955  -36.180  -27.086 1.00 31.86  ? 57   PHE B O     1 
ATOM   3768  C CB    . PHE B 1 57  ? -20.604  -38.940  -27.967 1.00 22.77  ? 57   PHE B CB    1 
ATOM   3769  C CG    . PHE B 1 57  ? -19.317  -39.601  -27.479 1.00 24.38  ? 57   PHE B CG    1 
ATOM   3770  C CD1   . PHE B 1 57  ? -19.351  -40.711  -26.630 1.00 20.84  ? 57   PHE B CD1   1 
ATOM   3771  C CD2   . PHE B 1 57  ? -18.081  -39.123  -27.898 1.00 23.87  ? 57   PHE B CD2   1 
ATOM   3772  C CE1   . PHE B 1 57  ? -18.185  -41.328  -26.214 1.00 23.14  ? 57   PHE B CE1   1 
ATOM   3773  C CE2   . PHE B 1 57  ? -16.907  -39.719  -27.474 1.00 25.01  ? 57   PHE B CE2   1 
ATOM   3774  C CZ    . PHE B 1 57  ? -16.956  -40.835  -26.640 1.00 27.14  ? 57   PHE B CZ    1 
ATOM   3775  N N     . ASP B 1 58  ? -20.091  -37.132  -25.061 1.00 28.85  ? 58   ASP B N     1 
ATOM   3776  C CA    . ASP B 1 58  ? -19.179  -36.193  -24.443 1.00 28.75  ? 58   ASP B CA    1 
ATOM   3777  C C     . ASP B 1 58  ? -18.124  -36.990  -23.684 1.00 26.78  ? 58   ASP B C     1 
ATOM   3778  O O     . ASP B 1 58  ? -18.378  -37.499  -22.571 1.00 29.44  ? 58   ASP B O     1 
ATOM   3779  C CB    . ASP B 1 58  ? -19.961  -35.234  -23.571 1.00 30.31  ? 58   ASP B CB    1 
ATOM   3780  C CG    . ASP B 1 58  ? -19.164  -34.147  -22.863 1.00 39.93  ? 58   ASP B CG    1 
ATOM   3781  O OD1   . ASP B 1 58  ? -17.894  -34.184  -22.917 1.00 39.57  ? 58   ASP B OD1   1 
ATOM   3782  O OD2   . ASP B 1 58  ? -19.827  -33.255  -22.288 1.00 45.84  ? 58   ASP B OD2   1 
ATOM   3783  N N     . ALA B 1 59  ? -16.936  -37.108  -24.294 1.00 23.83  ? 59   ALA B N     1 
ATOM   3784  C CA    . ALA B 1 59  ? -15.924  -37.984  -23.729 1.00 24.85  ? 59   ALA B CA    1 
ATOM   3785  C C     . ALA B 1 59  ? -15.501  -37.468  -22.351 1.00 26.13  ? 59   ALA B C     1 
ATOM   3786  O O     . ALA B 1 59  ? -15.114  -38.263  -21.491 1.00 24.82  ? 59   ALA B O     1 
ATOM   3787  C CB    . ALA B 1 59  ? -14.765  -38.112  -24.674 1.00 23.73  ? 59   ALA B CB    1 
ATOM   3788  N N     . LYS B 1 60  ? -15.581  -36.145  -22.146 1.00 28.94  ? 60   LYS B N     1 
ATOM   3789  C CA    . LYS B 1 60  ? -15.188  -35.570  -20.861 1.00 36.88  ? 60   LYS B CA    1 
ATOM   3790  C C     . LYS B 1 60  ? -16.156  -36.020  -19.772 1.00 29.55  ? 60   LYS B C     1 
ATOM   3791  O O     . LYS B 1 60  ? -15.710  -36.359  -18.688 1.00 29.14  ? 60   LYS B O     1 
ATOM   3792  C CB    . LYS B 1 60  ? -15.052  -34.040  -20.862 1.00 36.94  ? 60   LYS B CB    1 
ATOM   3793  C CG    . LYS B 1 60  ? -13.767  -33.567  -21.520 1.00 47.42  ? 60   LYS B CG    1 
ATOM   3794  C CD    . LYS B 1 60  ? -13.730  -32.117  -22.007 1.00 54.60  ? 60   LYS B CD    1 
ATOM   3795  C CE    . LYS B 1 60  ? -12.445  -31.933  -22.790 1.00 62.35  ? 60   LYS B CE    1 
ATOM   3796  N NZ    . LYS B 1 60  ? -12.485  -30.898  -23.830 1.00 59.68  ? 60   LYS B NZ    1 
ATOM   3797  N N     . LYS B 1 61  ? -17.456  -36.047  -20.077 1.00 29.62  ? 61   LYS B N     1 
ATOM   3798  C CA    . LYS B 1 61  ? -18.457  -36.506  -19.124 1.00 33.77  ? 61   LYS B CA    1 
ATOM   3799  C C     . LYS B 1 61  ? -18.214  -37.974  -18.772 1.00 31.09  ? 61   LYS B C     1 
ATOM   3800  O O     . LYS B 1 61  ? -18.285  -38.359  -17.609 1.00 32.69  ? 61   LYS B O     1 
ATOM   3801  C CB    . LYS B 1 61  ? -19.909  -36.244  -19.547 1.00 36.72  ? 61   LYS B CB    1 
ATOM   3802  C CG    . LYS B 1 61  ? -20.382  -34.825  -19.227 1.00 58.36  ? 61   LYS B CG    1 
ATOM   3803  C CD    . LYS B 1 61  ? -21.900  -34.635  -19.254 1.00 73.25  ? 61   LYS B CD    1 
ATOM   3804  C CE    . LYS B 1 61  ? -22.550  -34.662  -20.630 1.00 75.22  ? 61   LYS B CE    1 
ATOM   3805  N NZ    . LYS B 1 61  ? -23.243  -33.493  -21.194 1.00 60.60  ? 61   LYS B NZ    1 
ATOM   3806  N N     . ILE B 1 62  ? -17.894  -38.781  -19.787 1.00 28.75  ? 62   ILE B N     1 
ATOM   3807  C CA    . ILE B 1 62  ? -17.682  -40.197  -19.559 1.00 24.24  ? 62   ILE B CA    1 
ATOM   3808  C C     . ILE B 1 62  ? -16.446  -40.405  -18.687 1.00 25.13  ? 62   ILE B C     1 
ATOM   3809  O O     . ILE B 1 62  ? -16.493  -41.167  -17.724 1.00 24.54  ? 62   ILE B O     1 
ATOM   3810  C CB    . ILE B 1 62  ? -17.604  -40.927  -20.902 1.00 24.66  ? 62   ILE B CB    1 
ATOM   3811  C CG1   . ILE B 1 62  ? -18.976  -40.928  -21.550 1.00 27.48  ? 62   ILE B CG1   1 
ATOM   3812  C CG2   . ILE B 1 62  ? -17.040  -42.328  -20.716 1.00 22.65  ? 62   ILE B CG2   1 
ATOM   3813  C CD1   . ILE B 1 62  ? -19.001  -41.433  -22.967 1.00 26.37  ? 62   ILE B CD1   1 
ATOM   3814  N N     . ALA B 1 63  ? -15.353  -39.685  -18.985 1.00 22.46  ? 63   ALA B N     1 
ATOM   3815  C CA    . ALA B 1 63  ? -14.144  -39.839  -18.191 1.00 23.45  ? 63   ALA B CA    1 
ATOM   3816  C C     . ALA B 1 63  ? -14.388  -39.386  -16.750 1.00 25.99  ? 63   ALA B C     1 
ATOM   3817  O O     . ALA B 1 63  ? -13.936  -40.055  -15.821 1.00 26.49  ? 63   ALA B O     1 
ATOM   3818  C CB    . ALA B 1 63  ? -12.991  -39.093  -18.831 1.00 20.03  ? 63   ALA B CB    1 
ATOM   3819  N N     . HIS B 1 64  ? -15.131  -38.280  -16.572 1.00 25.31  ? 64   HIS B N     1 
ATOM   3820  C CA    . HIS B 1 64  ? -15.453  -37.779  -15.248 1.00 32.70  ? 64   HIS B CA    1 
ATOM   3821  C C     . HIS B 1 64  ? -16.239  -38.835  -14.458 1.00 31.26  ? 64   HIS B C     1 
ATOM   3822  O O     . HIS B 1 64  ? -15.925  -39.130  -13.303 1.00 32.36  ? 64   HIS B O     1 
ATOM   3823  C CB    . HIS B 1 64  ? -16.112  -36.387  -15.305 1.00 36.29  ? 64   HIS B CB    1 
ATOM   3824  C CG    . HIS B 1 64  ? -16.285  -35.793  -13.928 1.00 64.67  ? 64   HIS B CG    1 
ATOM   3825  N ND1   . HIS B 1 64  ? -15.278  -35.142  -13.231 1.00 72.99  ? 64   HIS B ND1   1 
ATOM   3826  C CD2   . HIS B 1 64  ? -17.362  -35.814  -13.092 1.00 61.83  ? 64   HIS B CD2   1 
ATOM   3827  C CE1   . HIS B 1 64  ? -15.737  -34.779  -12.036 1.00 73.06  ? 64   HIS B CE1   1 
ATOM   3828  N NE2   . HIS B 1 64  ? -16.993  -35.191  -11.931 1.00 65.64  ? 64   HIS B NE2   1 
ATOM   3829  N N     . ALA B 1 65  ? -17.266  -39.410  -15.091 1.00 25.53  ? 65   ALA B N     1 
ATOM   3830  C CA    . ALA B 1 65  ? -18.084  -40.410  -14.439 1.00 24.77  ? 65   ALA B CA    1 
ATOM   3831  C C     . ALA B 1 65  ? -17.230  -41.623  -14.043 1.00 25.35  ? 65   ALA B C     1 
ATOM   3832  O O     . ALA B 1 65  ? -17.376  -42.138  -12.939 1.00 29.16  ? 65   ALA B O     1 
ATOM   3833  C CB    . ALA B 1 65  ? -19.245  -40.794  -15.340 1.00 23.67  ? 65   ALA B CB    1 
ATOM   3834  N N     . ALA B 1 66  ? -16.324  -42.065  -14.919 1.00 21.35  ? 66   ALA B N     1 
ATOM   3835  C CA    . ALA B 1 66  ? -15.450  -43.176  -14.589 1.00 24.08  ? 66   ALA B CA    1 
ATOM   3836  C C     . ALA B 1 66  ? -14.572  -42.847  -13.374 1.00 24.47  ? 66   ALA B C     1 
ATOM   3837  O O     . ALA B 1 66  ? -14.374  -43.682  -12.492 1.00 24.40  ? 66   ALA B O     1 
ATOM   3838  C CB    . ALA B 1 66  ? -14.599  -43.537  -15.804 1.00 22.21  ? 66   ALA B CB    1 
ATOM   3839  N N     . LYS B 1 67  ? -14.027  -41.629  -13.332 1.00 23.98  ? 67   LYS B N     1 
ATOM   3840  C CA    . LYS B 1 67  ? -13.200  -41.200  -12.222 1.00 26.77  ? 67   LYS B CA    1 
ATOM   3841  C C     . LYS B 1 67  ? -14.017  -41.217  -10.928 1.00 27.78  ? 67   LYS B C     1 
ATOM   3842  O O     . LYS B 1 67  ? -13.563  -41.773  -9.931  1.00 28.05  ? 67   LYS B O     1 
ATOM   3843  C CB    . LYS B 1 67  ? -12.543  -39.833  -12.456 1.00 32.73  ? 67   LYS B CB    1 
ATOM   3844  C CG    . LYS B 1 67  ? -11.492  -39.495  -11.401 1.00 43.19  ? 67   LYS B CG    1 
ATOM   3845  C CD    . LYS B 1 67  ? -10.713  -38.210  -11.601 1.00 55.52  ? 67   LYS B CD    1 
ATOM   3846  C CE    . LYS B 1 67  ? -9.341   -38.284  -11.040 1.00 62.70  ? 67   LYS B CE    1 
ATOM   3847  N NZ    . LYS B 1 67  ? -8.643   -39.543  -11.314 1.00 63.72  ? 67   LYS B NZ    1 
ATOM   3848  N N     . ALA B 1 68  ? -15.237  -40.658  -10.955 1.00 25.16  ? 68   ALA B N     1 
ATOM   3849  C CA    . ALA B 1 68  ? -16.107  -40.574  -9.782  1.00 25.90  ? 68   ALA B CA    1 
ATOM   3850  C C     . ALA B 1 68  ? -16.469  -41.969  -9.276  1.00 25.71  ? 68   ALA B C     1 
ATOM   3851  O O     . ALA B 1 68  ? -16.642  -42.148  -8.090  1.00 30.92  ? 68   ALA B O     1 
ATOM   3852  C CB    . ALA B 1 68  ? -17.357  -39.757  -10.091 1.00 19.87  ? 68   ALA B CB    1 
ATOM   3853  N N     . VAL B 1 69  ? -16.611  -42.952  -10.165 1.00 25.17  ? 69   VAL B N     1 
ATOM   3854  C CA    . VAL B 1 69  ? -17.043  -44.274  -9.753  1.00 24.98  ? 69   VAL B CA    1 
ATOM   3855  C C     . VAL B 1 69  ? -15.838  -45.043  -9.196  1.00 24.26  ? 69   VAL B C     1 
ATOM   3856  O O     . VAL B 1 69  ? -15.995  -46.152  -8.686  1.00 25.12  ? 69   VAL B O     1 
ATOM   3857  C CB    . VAL B 1 69  ? -17.748  -45.041  -10.894 1.00 28.67  ? 69   VAL B CB    1 
ATOM   3858  C CG1   . VAL B 1 69  ? -16.782  -45.713  -11.847 1.00 27.27  ? 69   VAL B CG1   1 
ATOM   3859  C CG2   . VAL B 1 69  ? -18.608  -46.182  -10.376 1.00 42.87  ? 69   VAL B CG2   1 
ATOM   3860  N N     . GLY B 1 70  ? -14.631  -44.462  -9.293  1.00 21.05  ? 70   GLY B N     1 
ATOM   3861  C CA    . GLY B 1 70  ? -13.428  -45.123  -8.805  1.00 20.70  ? 70   GLY B CA    1 
ATOM   3862  C C     . GLY B 1 70  ? -12.754  -46.034  -9.837  1.00 22.72  ? 70   GLY B C     1 
ATOM   3863  O O     . GLY B 1 70  ? -11.836  -46.777  -9.465  1.00 21.79  ? 70   GLY B O     1 
ATOM   3864  N N     . ALA B 1 71  ? -13.177  -45.982  -11.120 1.00 18.03  ? 71   ALA B N     1 
ATOM   3865  C CA    . ALA B 1 71  ? -12.527  -46.758  -12.172 1.00 19.40  ? 71   ALA B CA    1 
ATOM   3866  C C     . ALA B 1 71  ? -11.169  -46.141  -12.502 1.00 20.59  ? 71   ALA B C     1 
ATOM   3867  O O     . ALA B 1 71  ? -10.999  -44.933  -12.399 1.00 22.85  ? 71   ALA B O     1 
ATOM   3868  C CB    . ALA B 1 71  ? -13.398  -46.837  -13.418 1.00 18.61  ? 71   ALA B CB    1 
ATOM   3869  N N     . LYS B 1 72  ? -10.201  -46.968  -12.909 1.00 22.80  ? 72   LYS B N     1 
ATOM   3870  C CA    . LYS B 1 72  ? -8.870   -46.475  -13.249 1.00 24.50  ? 72   LYS B CA    1 
ATOM   3871  C C     . LYS B 1 72  ? -8.581   -46.676  -14.741 1.00 27.33  ? 72   LYS B C     1 
ATOM   3872  O O     . LYS B 1 72  ? -7.527   -46.255  -15.232 1.00 28.93  ? 72   LYS B O     1 
ATOM   3873  C CB    . LYS B 1 72  ? -7.817   -47.173  -12.378 1.00 25.14  ? 72   LYS B CB    1 
ATOM   3874  C CG    . LYS B 1 72  ? -7.888   -46.832  -10.890 1.00 28.82  ? 72   LYS B CG    1 
ATOM   3875  C CD    . LYS B 1 72  ? -7.692   -45.350  -10.625 1.00 32.38  ? 72   LYS B CD    1 
ATOM   3876  C CE    . LYS B 1 72  ? -7.724   -44.877  -9.177  1.00 35.26  ? 72   LYS B CE    1 
ATOM   3877  N NZ    . LYS B 1 72  ? -6.668   -45.542  -8.416  1.00 39.41  ? 72   LYS B NZ    1 
ATOM   3878  N N     . TYR B 1 73  ? -9.508   -47.330  -15.460 1.00 22.62  ? 73   TYR B N     1 
ATOM   3879  C CA    . TYR B 1 73  ? -9.395   -47.456  -16.906 1.00 20.69  ? 73   TYR B CA    1 
ATOM   3880  C C     . TYR B 1 73  ? -10.789  -47.616  -17.514 1.00 22.51  ? 73   TYR B C     1 
ATOM   3881  O O     . TYR B 1 73  ? -11.752  -47.912  -16.800 1.00 24.61  ? 73   TYR B O     1 
ATOM   3882  C CB    . TYR B 1 73  ? -8.517   -48.647  -17.273 1.00 17.32  ? 73   TYR B CB    1 
ATOM   3883  C CG    . TYR B 1 73  ? -8.929   -50.064  -16.869 1.00 17.85  ? 73   TYR B CG    1 
ATOM   3884  C CD1   . TYR B 1 73  ? -9.042   -50.443  -15.524 1.00 16.66  ? 73   TYR B CD1   1 
ATOM   3885  C CD2   . TYR B 1 73  ? -9.113   -51.053  -17.839 1.00 18.27  ? 73   TYR B CD2   1 
ATOM   3886  C CE1   . TYR B 1 73  ? -9.333   -51.751  -15.165 1.00 16.86  ? 73   TYR B CE1   1 
ATOM   3887  C CE2   . TYR B 1 73  ? -9.410   -52.363  -17.498 1.00 17.29  ? 73   TYR B CE2   1 
ATOM   3888  C CZ    . TYR B 1 73  ? -9.513   -52.711  -16.152 1.00 19.92  ? 73   TYR B CZ    1 
ATOM   3889  O OH    . TYR B 1 73  ? -9.773   -54.025  -15.816 1.00 21.93  ? 73   TYR B OH    1 
ATOM   3890  N N     . ILE B 1 74  ? -10.874  -47.397  -18.830 1.00 19.01  ? 74   ILE B N     1 
ATOM   3891  C CA    . ILE B 1 74  ? -12.105  -47.521  -19.587 1.00 20.48  ? 74   ILE B CA    1 
ATOM   3892  C C     . ILE B 1 74  ? -11.804  -48.348  -20.835 1.00 22.99  ? 74   ILE B C     1 
ATOM   3893  O O     . ILE B 1 74  ? -10.826  -48.078  -21.533 1.00 19.76  ? 74   ILE B O     1 
ATOM   3894  C CB    . ILE B 1 74  ? -12.674  -46.149  -19.993 1.00 19.90  ? 74   ILE B CB    1 
ATOM   3895  C CG1   . ILE B 1 74  ? -12.852  -45.214  -18.788 1.00 19.56  ? 74   ILE B CG1   1 
ATOM   3896  C CG2   . ILE B 1 74  ? -13.987  -46.341  -20.745 1.00 20.86  ? 74   ILE B CG2   1 
ATOM   3897  C CD1   . ILE B 1 74  ? -13.299  -43.819  -19.184 1.00 17.05  ? 74   ILE B CD1   1 
ATOM   3898  N N     . VAL B 1 75  ? -12.640  -49.373  -21.072 1.00 22.03  ? 75   VAL B N     1 
ATOM   3899  C CA    . VAL B 1 75  ? -12.577  -50.133  -22.304 1.00 22.57  ? 75   VAL B CA    1 
ATOM   3900  C C     . VAL B 1 75  ? -13.735  -49.679  -23.189 1.00 24.54  ? 75   VAL B C     1 
ATOM   3901  O O     . VAL B 1 75  ? -14.882  -49.905  -22.822 1.00 27.61  ? 75   VAL B O     1 
ATOM   3902  C CB    . VAL B 1 75  ? -12.685  -51.628  -21.981 1.00 22.17  ? 75   VAL B CB    1 
ATOM   3903  C CG1   . VAL B 1 75  ? -12.575  -52.460  -23.264 1.00 19.49  ? 75   VAL B CG1   1 
ATOM   3904  C CG2   . VAL B 1 75  ? -11.613  -52.048  -20.981 1.00 21.37  ? 75   VAL B CG2   1 
ATOM   3905  N N     . LEU B 1 76  ? -13.424  -49.033  -24.325 1.00 23.62  ? 76   LEU B N     1 
ATOM   3906  C CA    . LEU B 1 76  ? -14.414  -48.568  -25.281 1.00 22.46  ? 76   LEU B CA    1 
ATOM   3907  C C     . LEU B 1 76  ? -14.427  -49.474  -26.522 1.00 23.42  ? 76   LEU B C     1 
ATOM   3908  O O     . LEU B 1 76  ? -13.368  -49.833  -27.054 1.00 23.83  ? 76   LEU B O     1 
ATOM   3909  C CB    . LEU B 1 76  ? -14.149  -47.113  -25.639 1.00 20.69  ? 76   LEU B CB    1 
ATOM   3910  C CG    . LEU B 1 76  ? -15.069  -46.490  -26.692 1.00 23.78  ? 76   LEU B CG    1 
ATOM   3911  C CD1   . LEU B 1 76  ? -16.522  -46.478  -26.229 1.00 24.15  ? 76   LEU B CD1   1 
ATOM   3912  C CD2   . LEU B 1 76  ? -14.634  -45.049  -26.991 1.00 21.24  ? 76   LEU B CD2   1 
ATOM   3913  N N     . THR B 1 77  ? -15.638  -49.871  -26.957 1.00 19.89  ? 77   THR B N     1 
ATOM   3914  C CA    . THR B 1 77  ? -15.772  -50.627  -28.200 1.00 19.06  ? 77   THR B CA    1 
ATOM   3915  C C     . THR B 1 77  ? -15.349  -49.748  -29.388 1.00 20.14  ? 77   THR B C     1 
ATOM   3916  O O     . THR B 1 77  ? -16.075  -48.817  -29.748 1.00 19.75  ? 77   THR B O     1 
ATOM   3917  C CB    . THR B 1 77  ? -17.218  -51.111  -28.362 1.00 17.81  ? 77   THR B CB    1 
ATOM   3918  O OG1   . THR B 1 77  ? -18.100  -49.991  -28.264 1.00 17.01  ? 77   THR B OG1   1 
ATOM   3919  C CG2   . THR B 1 77  ? -17.601  -52.199  -27.364 1.00 16.99  ? 77   THR B CG2   1 
ATOM   3920  N N     . THR B 1 78  ? -14.191  -50.019  -30.000 1.00 21.11  ? 78   THR B N     1 
ATOM   3921  C CA    . THR B 1 78  ? -13.759  -49.217  -31.149 1.00 22.03  ? 78   THR B CA    1 
ATOM   3922  C C     . THR B 1 78  ? -14.342  -49.770  -32.455 1.00 24.14  ? 78   THR B C     1 
ATOM   3923  O O     . THR B 1 78  ? -14.457  -49.038  -33.444 1.00 23.94  ? 78   THR B O     1 
ATOM   3924  C CB    . THR B 1 78  ? -12.238  -49.093  -31.238 1.00 21.21  ? 78   THR B CB    1 
ATOM   3925  O OG1   . THR B 1 78  ? -11.750  -50.376  -31.613 1.00 18.46  ? 78   THR B OG1   1 
ATOM   3926  C CG2   . THR B 1 78  ? -11.597  -48.582  -29.954 1.00 20.87  ? 78   THR B CG2   1 
ATOM   3927  N N     . LYS B 1 79  ? -14.674  -51.073  -32.449 1.00 23.00  ? 79   LYS B N     1 
ATOM   3928  C CA    . LYS B 1 79  ? -15.325  -51.767  -33.547 1.00 21.23  ? 79   LYS B CA    1 
ATOM   3929  C C     . LYS B 1 79  ? -15.895  -53.075  -32.996 1.00 21.22  ? 79   LYS B C     1 
ATOM   3930  O O     . LYS B 1 79  ? -15.129  -53.922  -32.515 1.00 25.60  ? 79   LYS B O     1 
ATOM   3931  C CB    . LYS B 1 79  ? -14.323  -52.116  -34.667 1.00 20.15  ? 79   LYS B CB    1 
ATOM   3932  C CG    . LYS B 1 79  ? -14.986  -52.669  -35.954 1.00 22.05  ? 79   LYS B CG    1 
ATOM   3933  C CD    . LYS B 1 79  ? -14.157  -53.656  -36.777 1.00 24.15  ? 79   LYS B CD    1 
ATOM   3934  C CE    . LYS B 1 79  ? -13.997  -54.994  -36.095 1.00 21.98  ? 79   LYS B CE    1 
ATOM   3935  N NZ    . LYS B 1 79  ? -13.233  -55.986  -36.887 1.00 23.98  ? 79   LYS B NZ    1 
ATOM   3936  N N     . HIS B 1 80  ? -17.230  -53.242  -33.068 1.00 19.79  ? 80   HIS B N     1 
ATOM   3937  C CA    . HIS B 1 80  ? -17.892  -54.456  -32.591 1.00 19.24  ? 80   HIS B CA    1 
ATOM   3938  C C     . HIS B 1 80  ? -18.088  -55.431  -33.766 1.00 22.64  ? 80   HIS B C     1 
ATOM   3939  O O     . HIS B 1 80  ? -17.593  -55.186  -34.872 1.00 20.74  ? 80   HIS B O     1 
ATOM   3940  C CB    . HIS B 1 80  ? -19.137  -54.099  -31.767 1.00 16.22  ? 80   HIS B CB    1 
ATOM   3941  C CG    . HIS B 1 80  ? -19.452  -55.117  -30.733 1.00 17.24  ? 80   HIS B CG    1 
ATOM   3942  N ND1   . HIS B 1 80  ? -20.231  -56.234  -30.970 1.00 19.13  ? 80   HIS B ND1   1 
ATOM   3943  C CD2   . HIS B 1 80  ? -19.058  -55.209  -29.426 1.00 19.22  ? 80   HIS B CD2   1 
ATOM   3944  C CE1   . HIS B 1 80  ? -20.320  -56.974  -29.862 1.00 18.36  ? 80   HIS B CE1   1 
ATOM   3945  N NE2   . HIS B 1 80  ? -19.618  -56.363  -28.896 1.00 17.51  ? 80   HIS B NE2   1 
ATOM   3946  N N     . HIS B 1 81  ? -18.829  -56.539  -33.554 1.00 22.80  ? 81   HIS B N     1 
ATOM   3947  C CA    . HIS B 1 81  ? -19.055  -57.498  -34.631 1.00 24.26  ? 81   HIS B CA    1 
ATOM   3948  C C     . HIS B 1 81  ? -19.666  -56.827  -35.867 1.00 24.72  ? 81   HIS B C     1 
ATOM   3949  O O     . HIS B 1 81  ? -19.350  -57.216  -36.996 1.00 26.85  ? 81   HIS B O     1 
ATOM   3950  C CB    . HIS B 1 81  ? -19.933  -58.659  -34.168 1.00 22.06  ? 81   HIS B CB    1 
ATOM   3951  C CG    . HIS B 1 81  ? -19.400  -59.359  -32.964 1.00 23.05  ? 81   HIS B CG    1 
ATOM   3952  N ND1   . HIS B 1 81  ? -18.093  -59.794  -32.898 1.00 27.38  ? 81   HIS B ND1   1 
ATOM   3953  C CD2   . HIS B 1 81  ? -19.972  -59.715  -31.784 1.00 23.44  ? 81   HIS B CD2   1 
ATOM   3954  C CE1   . HIS B 1 81  ? -17.883  -60.368  -31.709 1.00 27.25  ? 81   HIS B CE1   1 
ATOM   3955  N NE2   . HIS B 1 81  ? -19.019  -60.350  -31.030 1.00 23.70  ? 81   HIS B NE2   1 
ATOM   3956  N N     . GLU B 1 82  ? -20.539  -55.834  -35.662 1.00 22.88  ? 82   GLU B N     1 
ATOM   3957  C CA    . GLU B 1 82  ? -21.184  -55.163  -36.787 1.00 24.40  ? 82   GLU B CA    1 
ATOM   3958  C C     . GLU B 1 82  ? -20.127  -54.585  -37.733 1.00 24.09  ? 82   GLU B C     1 
ATOM   3959  O O     . GLU B 1 82  ? -20.426  -54.294  -38.876 1.00 24.61  ? 82   GLU B O     1 
ATOM   3960  C CB    . GLU B 1 82  ? -22.155  -54.069  -36.320 1.00 23.35  ? 82   GLU B CB    1 
ATOM   3961  C CG    . GLU B 1 82  ? -21.474  -53.017  -35.452 1.00 22.84  ? 82   GLU B CG    1 
ATOM   3962  C CD    . GLU B 1 82  ? -22.268  -51.781  -35.017 1.00 25.01  ? 82   GLU B CD    1 
ATOM   3963  O OE1   . GLU B 1 82  ? -23.528  -51.766  -35.121 1.00 22.21  ? 82   GLU B OE1   1 
ATOM   3964  O OE2   . GLU B 1 82  ? -21.604  -50.795  -34.579 1.00 22.16  ? 82   GLU B OE2   1 
ATOM   3965  N N     . GLY B 1 83  ? -18.908  -54.325  -37.237 1.00 26.18  ? 83   GLY B N     1 
ATOM   3966  C CA    . GLY B 1 83  ? -17.775  -53.994  -38.101 1.00 21.62  ? 83   GLY B CA    1 
ATOM   3967  C C     . GLY B 1 83  ? -17.639  -52.494  -38.387 1.00 23.65  ? 83   GLY B C     1 
ATOM   3968  O O     . GLY B 1 83  ? -16.813  -52.110  -39.216 1.00 22.39  ? 83   GLY B O     1 
ATOM   3969  N N     . PHE B 1 84  ? -18.429  -51.648  -37.705 1.00 21.62  ? 84   PHE B N     1 
ATOM   3970  C CA    . PHE B 1 84  ? -18.359  -50.199  -37.855 1.00 19.50  ? 84   PHE B CA    1 
ATOM   3971  C C     . PHE B 1 84  ? -17.291  -49.614  -36.922 1.00 23.41  ? 84   PHE B C     1 
ATOM   3972  O O     . PHE B 1 84  ? -17.264  -49.921  -35.728 1.00 24.86  ? 84   PHE B O     1 
ATOM   3973  C CB    . PHE B 1 84  ? -19.751  -49.638  -37.507 1.00 17.00  ? 84   PHE B CB    1 
ATOM   3974  C CG    . PHE B 1 84  ? -19.748  -48.120  -37.399 1.00 19.77  ? 84   PHE B CG    1 
ATOM   3975  C CD1   . PHE B 1 84  ? -19.644  -47.325  -38.537 1.00 19.59  ? 84   PHE B CD1   1 
ATOM   3976  C CD2   . PHE B 1 84  ? -19.836  -47.491  -36.154 1.00 19.36  ? 84   PHE B CD2   1 
ATOM   3977  C CE1   . PHE B 1 84  ? -19.652  -45.938  -38.429 1.00 22.70  ? 84   PHE B CE1   1 
ATOM   3978  C CE2   . PHE B 1 84  ? -19.843  -46.109  -36.040 1.00 20.41  ? 84   PHE B CE2   1 
ATOM   3979  C CZ    . PHE B 1 84  ? -19.738  -45.320  -37.179 1.00 21.53  ? 84   PHE B CZ    1 
ATOM   3980  N N     . PHE B 1 85  ? -16.437  -48.728  -37.450 1.00 21.40  ? 85   PHE B N     1 
ATOM   3981  C CA    . PHE B 1 85  ? -15.319  -48.205  -36.677 1.00 20.79  ? 85   PHE B CA    1 
ATOM   3982  C C     . PHE B 1 85  ? -15.619  -46.826  -36.108 1.00 21.69  ? 85   PHE B C     1 
ATOM   3983  O O     . PHE B 1 85  ? -16.045  -45.933  -36.838 1.00 25.01  ? 85   PHE B O     1 
ATOM   3984  C CB    . PHE B 1 85  ? -14.073  -48.078  -37.547 1.00 18.65  ? 85   PHE B CB    1 
ATOM   3985  C CG    . PHE B 1 85  ? -13.561  -49.366  -38.181 1.00 20.52  ? 85   PHE B CG    1 
ATOM   3986  C CD1   . PHE B 1 85  ? -14.059  -49.794  -39.417 1.00 21.41  ? 85   PHE B CD1   1 
ATOM   3987  C CD2   . PHE B 1 85  ? -12.527  -50.089  -37.583 1.00 19.57  ? 85   PHE B CD2   1 
ATOM   3988  C CE1   . PHE B 1 85  ? -13.564  -50.961  -40.008 1.00 23.36  ? 85   PHE B CE1   1 
ATOM   3989  C CE2   . PHE B 1 85  ? -12.037  -51.254  -38.176 1.00 22.26  ? 85   PHE B CE2   1 
ATOM   3990  C CZ    . PHE B 1 85  ? -12.542  -51.681  -39.398 1.00 21.17  ? 85   PHE B CZ    1 
ATOM   3991  N N     . LEU B 1 86  ? -15.337  -46.643  -34.820 1.00 22.78  ? 86   LEU B N     1 
ATOM   3992  C CA    . LEU B 1 86  ? -15.615  -45.377  -34.151 1.00 22.91  ? 86   LEU B CA    1 
ATOM   3993  C C     . LEU B 1 86  ? -14.442  -44.397  -34.309 1.00 22.85  ? 86   LEU B C     1 
ATOM   3994  O O     . LEU B 1 86  ? -14.394  -43.368  -33.644 1.00 23.84  ? 86   LEU B O     1 
ATOM   3995  C CB    . LEU B 1 86  ? -15.960  -45.617  -32.683 1.00 22.79  ? 86   LEU B CB    1 
ATOM   3996  C CG    . LEU B 1 86  ? -17.429  -45.965  -32.395 1.00 26.24  ? 86   LEU B CG    1 
ATOM   3997  C CD1   . LEU B 1 86  ? -17.809  -47.379  -32.835 1.00 20.33  ? 86   LEU B CD1   1 
ATOM   3998  C CD2   . LEU B 1 86  ? -17.658  -45.831  -30.910 1.00 23.63  ? 86   LEU B CD2   1 
ATOM   3999  N N     . TYR B 1 87  ? -13.487  -44.720  -35.184 1.00 22.24  ? 87   TYR B N     1 
ATOM   4000  C CA    . TYR B 1 87  ? -12.346  -43.848  -35.400 1.00 25.98  ? 87   TYR B CA    1 
ATOM   4001  C C     . TYR B 1 87  ? -12.043  -43.717  -36.896 1.00 28.90  ? 87   TYR B C     1 
ATOM   4002  O O     . TYR B 1 87  ? -12.629  -44.416  -37.723 1.00 25.32  ? 87   TYR B O     1 
ATOM   4003  C CB    . TYR B 1 87  ? -11.128  -44.391  -34.644 1.00 22.85  ? 87   TYR B CB    1 
ATOM   4004  C CG    . TYR B 1 87  ? -10.705  -45.808  -35.011 1.00 22.87  ? 87   TYR B CG    1 
ATOM   4005  C CD1   . TYR B 1 87  ? -11.385  -46.913  -34.517 1.00 20.94  ? 87   TYR B CD1   1 
ATOM   4006  C CD2   . TYR B 1 87  ? -9.600   -46.042  -35.832 1.00 22.82  ? 87   TYR B CD2   1 
ATOM   4007  C CE1   . TYR B 1 87  ? -10.977  -48.206  -34.820 1.00 21.17  ? 87   TYR B CE1   1 
ATOM   4008  C CE2   . TYR B 1 87  ? -9.166   -47.335  -36.117 1.00 20.49  ? 87   TYR B CE2   1 
ATOM   4009  C CZ    . TYR B 1 87  ? -9.849   -48.420  -35.601 1.00 22.82  ? 87   TYR B CZ    1 
ATOM   4010  O OH    . TYR B 1 87  ? -9.430   -49.703  -35.871 1.00 23.22  ? 87   TYR B OH    1 
ATOM   4011  N N     . ASP B 1 88  ? -11.101  -42.815  -37.225 1.00 29.03  ? 88   ASP B N     1 
ATOM   4012  C CA    . ASP B 1 88  ? -10.705  -42.600  -38.599 1.00 28.88  ? 88   ASP B CA    1 
ATOM   4013  C C     . ASP B 1 88  ? -9.778   -43.733  -39.048 1.00 28.30  ? 88   ASP B C     1 
ATOM   4014  O O     . ASP B 1 88  ? -8.622   -43.801  -38.623 1.00 29.58  ? 88   ASP B O     1 
ATOM   4015  C CB    . ASP B 1 88  ? -10.017  -41.258  -38.721 1.00 31.10  ? 88   ASP B CB    1 
ATOM   4016  C CG    . ASP B 1 88  ? -9.633   -40.839  -40.140 1.00 37.68  ? 88   ASP B CG    1 
ATOM   4017  O OD1   . ASP B 1 88  ? -9.628   -41.696  -41.062 1.00 35.92  ? 88   ASP B OD1   1 
ATOM   4018  O OD2   . ASP B 1 88  ? -9.372   -39.631  -40.321 1.00 38.33  ? 88   ASP B OD2   1 
ATOM   4019  N N     . THR B 1 89  ? -10.266  -44.598  -39.949 1.00 29.82  ? 89   THR B N     1 
ATOM   4020  C CA    . THR B 1 89  ? -9.451   -45.735  -40.355 1.00 30.19  ? 89   THR B CA    1 
ATOM   4021  C C     . THR B 1 89  ? -8.486   -45.341  -41.486 1.00 32.65  ? 89   THR B C     1 
ATOM   4022  O O     . THR B 1 89  ? -7.805   -46.221  -42.014 1.00 32.09  ? 89   THR B O     1 
ATOM   4023  C CB    . THR B 1 89  ? -10.311  -46.931  -40.764 1.00 28.53  ? 89   THR B CB    1 
ATOM   4024  O OG1   . THR B 1 89  ? -11.041  -46.562  -41.939 1.00 32.16  ? 89   THR B OG1   1 
ATOM   4025  C CG2   . THR B 1 89  ? -11.296  -47.321  -39.689 1.00 25.07  ? 89   THR B CG2   1 
ATOM   4026  N N     . LYS B 1 90  ? -8.464   -44.052  -41.873 1.00 32.27  ? 90   LYS B N     1 
ATOM   4027  C CA    . LYS B 1 90  ? -7.472   -43.508  -42.802 1.00 42.12  ? 90   LYS B CA    1 
ATOM   4028  C C     . LYS B 1 90  ? -7.483   -44.267  -44.132 1.00 42.83  ? 90   LYS B C     1 
ATOM   4029  O O     . LYS B 1 90  ? -6.422   -44.622  -44.632 1.00 44.45  ? 90   LYS B O     1 
ATOM   4030  C CB    . LYS B 1 90  ? -6.054   -43.557  -42.219 1.00 41.96  ? 90   LYS B CB    1 
ATOM   4031  C CG    . LYS B 1 90  ? -5.923   -42.814  -40.898 1.00 49.65  ? 90   LYS B CG    1 
ATOM   4032  C CD    . LYS B 1 90  ? -4.493   -42.492  -40.454 1.00 73.26  ? 90   LYS B CD    1 
ATOM   4033  C CE    . LYS B 1 90  ? -4.122   -41.088  -40.863 1.00 82.42  ? 90   LYS B CE    1 
ATOM   4034  N NZ    . LYS B 1 90  ? -5.264   -40.185  -40.614 1.00 75.19  ? 90   LYS B NZ    1 
ATOM   4035  N N     . GLY B 1 91  ? -8.675   -44.573  -44.669 1.00 38.57  ? 91   GLY B N     1 
ATOM   4036  C CA    . GLY B 1 91  ? -8.795   -45.246  -45.947 1.00 30.88  ? 91   GLY B CA    1 
ATOM   4037  C C     . GLY B 1 91  ? -8.964   -46.759  -45.848 1.00 32.27  ? 91   GLY B C     1 
ATOM   4038  O O     . GLY B 1 91  ? -9.290   -47.389  -46.842 1.00 36.76  ? 91   GLY B O     1 
ATOM   4039  N N     . LEU B 1 92  ? -8.775   -47.367  -44.670 1.00 28.10  ? 92   LEU B N     1 
ATOM   4040  C CA    . LEU B 1 92  ? -8.948   -48.814  -44.614 1.00 26.90  ? 92   LEU B CA    1 
ATOM   4041  C C     . LEU B 1 92  ? -10.403  -49.208  -44.903 1.00 32.31  ? 92   LEU B C     1 
ATOM   4042  O O     . LEU B 1 92  ? -10.646  -50.253  -45.503 1.00 27.62  ? 92   LEU B O     1 
ATOM   4043  C CB    . LEU B 1 92  ? -8.504   -49.364  -43.270 1.00 26.88  ? 92   LEU B CB    1 
ATOM   4044  C CG    . LEU B 1 92  ? -8.723   -50.872  -43.094 1.00 32.49  ? 92   LEU B CG    1 
ATOM   4045  C CD1   . LEU B 1 92  ? -7.707   -51.653  -43.961 1.00 25.79  ? 92   LEU B CD1   1 
ATOM   4046  C CD2   . LEU B 1 92  ? -8.632   -51.251  -41.621 1.00 24.40  ? 92   LEU B CD2   1 
ATOM   4047  N N     . SER B 1 93  ? -11.375  -48.385  -44.463 1.00 29.20  ? 93   SER B N     1 
ATOM   4048  C CA    . SER B 1 93  ? -12.773  -48.730  -44.646 1.00 29.01  ? 93   SER B CA    1 
ATOM   4049  C C     . SER B 1 93  ? -13.606  -47.460  -44.772 1.00 28.57  ? 93   SER B C     1 
ATOM   4050  O O     . SER B 1 93  ? -13.287  -46.442  -44.182 1.00 29.83  ? 93   SER B O     1 
ATOM   4051  C CB    . SER B 1 93  ? -13.268  -49.567  -43.485 1.00 30.22  ? 93   SER B CB    1 
ATOM   4052  O OG    . SER B 1 93  ? -14.689  -49.718  -43.510 1.00 29.70  ? 93   SER B OG    1 
ATOM   4053  N N     . ASP B 1 94  ? -14.697  -47.518  -45.526 1.00 29.89  ? 94   ASP B N     1 
ATOM   4054  C CA    . ASP B 1 94  ? -15.658  -46.427  -45.598 1.00 36.82  ? 94   ASP B CA    1 
ATOM   4055  C C     . ASP B 1 94  ? -16.713  -46.540  -44.496 1.00 33.87  ? 94   ASP B C     1 
ATOM   4056  O O     . ASP B 1 94  ? -17.538  -45.638  -44.345 1.00 32.35  ? 94   ASP B O     1 
ATOM   4057  C CB    . ASP B 1 94  ? -16.394  -46.484  -46.929 1.00 45.42  ? 94   ASP B CB    1 
ATOM   4058  C CG    . ASP B 1 94  ? -15.589  -45.981  -48.123 1.00 65.78  ? 94   ASP B CG    1 
ATOM   4059  O OD1   . ASP B 1 94  ? -14.537  -45.327  -47.899 1.00 60.43  ? 94   ASP B OD1   1 
ATOM   4060  O OD2   . ASP B 1 94  ? -16.020  -46.231  -49.272 1.00 74.66  ? 94   ASP B OD2   1 
ATOM   4061  N N     . PHE B 1 95  ? -16.720  -47.671  -43.775 1.00 25.97  ? 95   PHE B N     1 
ATOM   4062  C CA    . PHE B 1 95  ? -17.740  -47.901  -42.764 1.00 26.29  ? 95   PHE B CA    1 
ATOM   4063  C C     . PHE B 1 95  ? -17.182  -47.434  -41.412 1.00 25.56  ? 95   PHE B C     1 
ATOM   4064  O O     . PHE B 1 95  ? -16.911  -48.243  -40.532 1.00 24.54  ? 95   PHE B O     1 
ATOM   4065  C CB    . PHE B 1 95  ? -18.086  -49.391  -42.835 1.00 22.59  ? 95   PHE B CB    1 
ATOM   4066  C CG    . PHE B 1 95  ? -19.379  -49.785  -42.134 1.00 22.27  ? 95   PHE B CG    1 
ATOM   4067  C CD1   . PHE B 1 95  ? -20.559  -49.070  -42.365 1.00 19.92  ? 95   PHE B CD1   1 
ATOM   4068  C CD2   . PHE B 1 95  ? -19.408  -50.884  -41.262 1.00 21.38  ? 95   PHE B CD2   1 
ATOM   4069  C CE1   . PHE B 1 95  ? -21.743  -49.437  -41.733 1.00 19.00  ? 95   PHE B CE1   1 
ATOM   4070  C CE2   . PHE B 1 95  ? -20.580  -51.274  -40.633 1.00 17.73  ? 95   PHE B CE2   1 
ATOM   4071  C CZ    . PHE B 1 95  ? -21.748  -50.528  -40.850 1.00 19.28  ? 95   PHE B CZ    1 
ATOM   4072  N N     . ASP B 1 96  ? -16.933  -46.125  -41.296 1.00 23.33  ? 96   ASP B N     1 
ATOM   4073  C CA    . ASP B 1 96  ? -16.311  -45.565  -40.111 1.00 25.77  ? 96   ASP B CA    1 
ATOM   4074  C C     . ASP B 1 96  ? -16.952  -44.211  -39.821 1.00 26.95  ? 96   ASP B C     1 
ATOM   4075  O O     . ASP B 1 96  ? -17.731  -43.679  -40.602 1.00 27.48  ? 96   ASP B O     1 
ATOM   4076  C CB    . ASP B 1 96  ? -14.782  -45.576  -40.203 1.00 28.43  ? 96   ASP B CB    1 
ATOM   4077  C CG    . ASP B 1 96  ? -14.118  -44.477  -41.045 1.00 31.53  ? 96   ASP B CG    1 
ATOM   4078  O OD1   . ASP B 1 96  ? -14.828  -43.521  -41.456 1.00 34.86  ? 96   ASP B OD1   1 
ATOM   4079  O OD2   . ASP B 1 96  ? -12.868  -44.574  -41.284 1.00 33.35  ? 96   ASP B OD2   1 
ATOM   4080  N N     . VAL B 1 97  ? -16.570  -43.631  -38.690 1.00 27.97  ? 97   VAL B N     1 
ATOM   4081  C CA    . VAL B 1 97  ? -17.257  -42.468  -38.183 1.00 23.50  ? 97   VAL B CA    1 
ATOM   4082  C C     . VAL B 1 97  ? -16.987  -41.258  -39.076 1.00 27.69  ? 97   VAL B C     1 
ATOM   4083  O O     . VAL B 1 97  ? -17.787  -40.311  -39.080 1.00 30.55  ? 97   VAL B O     1 
ATOM   4084  C CB    . VAL B 1 97  ? -16.807  -42.244  -36.726 1.00 24.40  ? 97   VAL B CB    1 
ATOM   4085  C CG1   . VAL B 1 97  ? -15.318  -41.903  -36.653 1.00 22.02  ? 97   VAL B CG1   1 
ATOM   4086  C CG2   . VAL B 1 97  ? -17.681  -41.177  -36.053 1.00 20.41  ? 97   VAL B CG2   1 
ATOM   4087  N N     . MET B 1 98  ? -15.876  -41.268  -39.829 1.00 25.12  ? 98   MET B N     1 
ATOM   4088  C CA    . MET B 1 98  ? -15.598  -40.152  -40.741 1.00 31.65  ? 98   MET B CA    1 
ATOM   4089  C C     . MET B 1 98  ? -16.581  -40.120  -41.910 1.00 30.94  ? 98   MET B C     1 
ATOM   4090  O O     . MET B 1 98  ? -16.742  -39.090  -42.525 1.00 34.88  ? 98   MET B O     1 
ATOM   4091  C CB    . MET B 1 98  ? -14.153  -40.131  -41.248 1.00 29.26  ? 98   MET B CB    1 
ATOM   4092  C CG    . MET B 1 98  ? -13.136  -40.077  -40.095 1.00 36.49  ? 98   MET B CG    1 
ATOM   4093  S SD    . MET B 1 98  ? -13.371  -38.815  -38.806 1.00 44.11  ? 98   MET B SD    1 
ATOM   4094  C CE    . MET B 1 98  ? -13.143  -37.252  -39.682 1.00 38.56  ? 98   MET B CE    1 
ATOM   4095  N N     . HIS B 1 99  ? -17.300  -41.219  -42.160 1.00 30.77  ? 99   HIS B N     1 
ATOM   4096  C CA    . HIS B 1 99  ? -18.304  -41.267  -43.211 1.00 31.73  ? 99   HIS B CA    1 
ATOM   4097  C C     . HIS B 1 99  ? -19.706  -41.162  -42.602 1.00 32.30  ? 99   HIS B C     1 
ATOM   4098  O O     . HIS B 1 99  ? -20.695  -41.483  -43.262 1.00 30.65  ? 99   HIS B O     1 
ATOM   4099  C CB    . HIS B 1 99  ? -18.148  -42.554  -44.037 1.00 28.46  ? 99   HIS B CB    1 
ATOM   4100  C CG    . HIS B 1 99  ? -16.852  -42.544  -44.788 1.00 38.86  ? 99   HIS B CG    1 
ATOM   4101  N ND1   . HIS B 1 99  ? -15.627  -42.786  -44.178 1.00 40.06  ? 99   HIS B ND1   1 
ATOM   4102  C CD2   . HIS B 1 99  ? -16.579  -42.251  -46.085 1.00 35.51  ? 99   HIS B CD2   1 
ATOM   4103  C CE1   . HIS B 1 99  ? -14.662  -42.691  -45.082 1.00 38.59  ? 99   HIS B CE1   1 
ATOM   4104  N NE2   . HIS B 1 99  ? -15.222  -42.369  -46.245 1.00 36.19  ? 99   HIS B NE2   1 
ATOM   4105  N N     . ALA B 1 100 ? -19.785  -40.799  -41.323 1.00 25.45  ? 100  ALA B N     1 
ATOM   4106  C CA    . ALA B 1 100 ? -21.074  -40.628  -40.671 1.00 26.25  ? 100  ALA B CA    1 
ATOM   4107  C C     . ALA B 1 100 ? -21.272  -39.139  -40.424 1.00 26.70  ? 100  ALA B C     1 
ATOM   4108  O O     . ALA B 1 100 ? -20.291  -38.393  -40.361 1.00 27.88  ? 100  ALA B O     1 
ATOM   4109  C CB    . ALA B 1 100 ? -21.099  -41.393  -39.354 1.00 24.59  ? 100  ALA B CB    1 
ATOM   4110  N N     . PRO B 1 101 ? -22.513  -38.647  -40.233 1.00 26.85  ? 101  PRO B N     1 
ATOM   4111  C CA    . PRO B 1 101 ? -22.705  -37.235  -39.885 1.00 26.88  ? 101  PRO B CA    1 
ATOM   4112  C C     . PRO B 1 101 ? -21.842  -36.749  -38.718 1.00 27.37  ? 101  PRO B C     1 
ATOM   4113  O O     . PRO B 1 101 ? -21.480  -35.590  -38.687 1.00 31.66  ? 101  PRO B O     1 
ATOM   4114  C CB    . PRO B 1 101 ? -24.211  -37.028  -39.745 1.00 20.24  ? 101  PRO B CB    1 
ATOM   4115  C CG    . PRO B 1 101 ? -24.763  -38.446  -39.679 1.00 25.75  ? 101  PRO B CG    1 
ATOM   4116  C CD    . PRO B 1 101 ? -23.769  -39.388  -40.381 1.00 25.70  ? 101  PRO B CD    1 
ATOM   4117  N N     . ALA B 1 102 ? -21.480  -37.626  -37.775 1.00 30.51  ? 102  ALA B N     1 
ATOM   4118  C CA    . ALA B 1 102 ? -20.659  -37.192  -36.648 1.00 27.49  ? 102  ALA B CA    1 
ATOM   4119  C C     . ALA B 1 102 ? -19.379  -36.502  -37.129 1.00 31.04  ? 102  ALA B C     1 
ATOM   4120  O O     . ALA B 1 102 ? -18.992  -35.480  -36.553 1.00 31.95  ? 102  ALA B O     1 
ATOM   4121  C CB    . ALA B 1 102 ? -20.330  -38.373  -35.756 1.00 21.65  ? 102  ALA B CB    1 
ATOM   4122  N N     . ARG B 1 103 ? -18.701  -37.100  -38.127 1.00 31.09  ? 103  ARG B N     1 
ATOM   4123  C CA    . ARG B 1 103 ? -17.468  -36.580  -38.702 1.00 39.27  ? 103  ARG B CA    1 
ATOM   4124  C C     . ARG B 1 103 ? -16.440  -36.189  -37.646 1.00 37.01  ? 103  ARG B C     1 
ATOM   4125  O O     . ARG B 1 103 ? -15.801  -35.159  -37.785 1.00 38.57  ? 103  ARG B O     1 
ATOM   4126  C CB    . ARG B 1 103 ? -17.670  -35.340  -39.584 1.00 43.33  ? 103  ARG B CB    1 
ATOM   4127  C CG    . ARG B 1 103 ? -18.249  -35.650  -40.955 1.00 61.33  ? 103  ARG B CG    1 
ATOM   4128  C CD    . ARG B 1 103 ? -17.483  -34.769  -41.975 1.00 89.49  ? 103  ARG B CD    1 
ATOM   4129  N NE    . ARG B 1 103 ? -18.269  -34.479  -43.180 1.00 118.25 ? 103  ARG B NE    1 
ATOM   4130  C CZ    . ARG B 1 103 ? -19.064  -33.423  -43.421 1.00 120.52 ? 103  ARG B CZ    1 
ATOM   4131  N NH1   . ARG B 1 103 ? -19.396  -32.569  -42.461 1.00 114.15 ? 103  ARG B NH1   1 
ATOM   4132  N NH2   . ARG B 1 103 ? -19.581  -33.261  -44.628 1.00 111.57 ? 103  ARG B NH2   1 
ATOM   4133  N N     . ARG B 1 104 ? -16.285  -36.996  -36.596 1.00 35.01  ? 104  ARG B N     1 
ATOM   4134  C CA    . ARG B 1 104 ? -15.309  -36.722  -35.555 1.00 33.48  ? 104  ARG B CA    1 
ATOM   4135  C C     . ARG B 1 104 ? -14.653  -38.050  -35.205 1.00 36.32  ? 104  ARG B C     1 
ATOM   4136  O O     . ARG B 1 104 ? -15.342  -39.085  -35.160 1.00 32.33  ? 104  ARG B O     1 
ATOM   4137  C CB    . ARG B 1 104 ? -16.015  -36.310  -34.257 1.00 33.50  ? 104  ARG B CB    1 
ATOM   4138  C CG    . ARG B 1 104 ? -16.700  -34.942  -34.260 1.00 33.75  ? 104  ARG B CG    1 
ATOM   4139  C CD    . ARG B 1 104 ? -17.993  -34.921  -33.431 1.00 30.99  ? 104  ARG B CD    1 
ATOM   4140  N NE    . ARG B 1 104 ? -17.779  -35.258  -32.018 1.00 30.29  ? 104  ARG B NE    1 
ATOM   4141  C CZ    . ARG B 1 104 ? -18.762  -35.488  -31.147 1.00 38.96  ? 104  ARG B CZ    1 
ATOM   4142  N NH1   . ARG B 1 104 ? -20.012  -35.387  -31.559 1.00 34.45  ? 104  ARG B NH1   1 
ATOM   4143  N NH2   . ARG B 1 104 ? -18.482  -35.822  -29.874 1.00 32.97  ? 104  ARG B NH2   1 
ATOM   4144  N N     . ASP B 1 105 ? -13.337  -38.014  -34.955 1.00 29.50  ? 105  ASP B N     1 
ATOM   4145  C CA    . ASP B 1 105 ? -12.673  -39.198  -34.438 1.00 31.39  ? 105  ASP B CA    1 
ATOM   4146  C C     . ASP B 1 105 ? -12.987  -39.360  -32.939 1.00 29.98  ? 105  ASP B C     1 
ATOM   4147  O O     . ASP B 1 105 ? -12.384  -38.697  -32.095 1.00 32.69  ? 105  ASP B O     1 
ATOM   4148  C CB    . ASP B 1 105 ? -11.195  -39.197  -34.794 1.00 26.80  ? 105  ASP B CB    1 
ATOM   4149  C CG    . ASP B 1 105 ? -10.519  -40.517  -34.480 1.00 32.64  ? 105  ASP B CG    1 
ATOM   4150  O OD1   . ASP B 1 105 ? -10.925  -41.136  -33.461 1.00 35.59  ? 105  ASP B OD1   1 
ATOM   4151  O OD2   . ASP B 1 105 ? -9.579   -40.918  -35.227 1.00 30.99  ? 105  ASP B OD2   1 
ATOM   4152  N N     . LEU B 1 106 ? -13.909  -40.274  -32.616 1.00 27.37  ? 106  LEU B N     1 
ATOM   4153  C CA    . LEU B 1 106 ? -14.414  -40.445  -31.256 1.00 24.73  ? 106  LEU B CA    1 
ATOM   4154  C C     . LEU B 1 106 ? -13.347  -41.069  -30.360 1.00 24.77  ? 106  LEU B C     1 
ATOM   4155  O O     . LEU B 1 106 ? -13.252  -40.724  -29.179 1.00 23.88  ? 106  LEU B O     1 
ATOM   4156  C CB    . LEU B 1 106 ? -15.695  -41.263  -31.289 1.00 24.89  ? 106  LEU B CB    1 
ATOM   4157  C CG    . LEU B 1 106 ? -16.800  -40.661  -32.168 1.00 26.01  ? 106  LEU B CG    1 
ATOM   4158  C CD1   . LEU B 1 106 ? -17.914  -41.656  -32.406 1.00 23.91  ? 106  LEU B CD1   1 
ATOM   4159  C CD2   . LEU B 1 106 ? -17.290  -39.347  -31.553 1.00 22.72  ? 106  LEU B CD2   1 
ATOM   4160  N N     . ILE B 1 107 ? -12.500  -41.929  -30.942 1.00 22.21  ? 107  ILE B N     1 
ATOM   4161  C CA    . ILE B 1 107 ? -11.390  -42.472  -30.187 1.00 25.57  ? 107  ILE B CA    1 
ATOM   4162  C C     . ILE B 1 107 ? -10.409  -41.358  -29.775 1.00 31.27  ? 107  ILE B C     1 
ATOM   4163  O O     . ILE B 1 107 ? -9.871   -41.399  -28.668 1.00 34.13  ? 107  ILE B O     1 
ATOM   4164  C CB    . ILE B 1 107 ? -10.726  -43.646  -30.932 1.00 27.06  ? 107  ILE B CB    1 
ATOM   4165  C CG1   . ILE B 1 107 ? -11.706  -44.790  -31.265 1.00 22.94  ? 107  ILE B CG1   1 
ATOM   4166  C CG2   . ILE B 1 107 ? -9.457   -44.141  -30.227 1.00 25.74  ? 107  ILE B CG2   1 
ATOM   4167  C CD1   . ILE B 1 107 ? -12.754  -45.075  -30.222 1.00 26.40  ? 107  ILE B CD1   1 
ATOM   4168  N N     . ALA B 1 108 ? -10.200  -40.343  -30.633 1.00 28.73  ? 108  ALA B N     1 
ATOM   4169  C CA    . ALA B 1 108 ? -9.294   -39.258  -30.276 1.00 28.49  ? 108  ALA B CA    1 
ATOM   4170  C C     . ALA B 1 108 ? -9.880   -38.473  -29.102 1.00 26.15  ? 108  ALA B C     1 
ATOM   4171  O O     . ALA B 1 108 ? -9.164   -38.134  -28.163 1.00 28.31  ? 108  ALA B O     1 
ATOM   4172  C CB    . ALA B 1 108 ? -8.944   -38.340  -31.451 1.00 22.00  ? 108  ALA B CB    1 
ATOM   4173  N N     . GLU B 1 109 ? -11.189  -38.203  -29.154 1.00 27.55  ? 109  GLU B N     1 
ATOM   4174  C CA    . GLU B 1 109 ? -11.852  -37.517  -28.045 1.00 28.46  ? 109  GLU B CA    1 
ATOM   4175  C C     . GLU B 1 109 ? -11.718  -38.326  -26.749 1.00 30.31  ? 109  GLU B C     1 
ATOM   4176  O O     . GLU B 1 109 ? -11.411  -37.759  -25.703 1.00 27.17  ? 109  GLU B O     1 
ATOM   4177  C CB    . GLU B 1 109 ? -13.311  -37.243  -28.373 1.00 27.73  ? 109  GLU B CB    1 
ATOM   4178  C CG    . GLU B 1 109 ? -13.465  -36.325  -29.581 1.00 29.31  ? 109  GLU B CG    1 
ATOM   4179  C CD    . GLU B 1 109 ? -14.914  -36.042  -29.916 1.00 33.82  ? 109  GLU B CD    1 
ATOM   4180  O OE1   . GLU B 1 109 ? -15.791  -36.519  -29.145 1.00 33.55  ? 109  GLU B OE1   1 
ATOM   4181  O OE2   . GLU B 1 109 ? -15.188  -35.375  -30.952 1.00 34.31  ? 109  GLU B OE2   1 
ATOM   4182  N N     . PHE B 1 110 ? -11.868  -39.662  -26.862 1.00 26.73  ? 110  PHE B N     1 
ATOM   4183  C CA    . PHE B 1 110 ? -11.862  -40.552  -25.721 1.00 25.98  ? 110  PHE B CA    1 
ATOM   4184  C C     . PHE B 1 110 ? -10.483  -40.563  -25.065 1.00 28.16  ? 110  PHE B C     1 
ATOM   4185  O O     . PHE B 1 110 ? -10.366  -40.485  -23.852 1.00 26.29  ? 110  PHE B O     1 
ATOM   4186  C CB    . PHE B 1 110 ? -12.274  -41.931  -26.243 1.00 24.66  ? 110  PHE B CB    1 
ATOM   4187  C CG    . PHE B 1 110 ? -12.011  -43.077  -25.289 1.00 22.55  ? 110  PHE B CG    1 
ATOM   4188  C CD1   . PHE B 1 110 ? -12.724  -43.198  -24.097 1.00 23.50  ? 110  PHE B CD1   1 
ATOM   4189  C CD2   . PHE B 1 110 ? -11.090  -44.065  -25.607 1.00 21.48  ? 110  PHE B CD2   1 
ATOM   4190  C CE1   . PHE B 1 110 ? -12.494  -44.263  -23.223 1.00 20.26  ? 110  PHE B CE1   1 
ATOM   4191  C CE2   . PHE B 1 110 ? -10.868  -45.156  -24.737 1.00 21.17  ? 110  PHE B CE2   1 
ATOM   4192  C CZ    . PHE B 1 110 ? -11.571  -45.244  -23.545 1.00 22.88  ? 110  PHE B CZ    1 
ATOM   4193  N N     . VAL B 1 111 ? -9.436   -40.681  -25.877 1.00 27.59  ? 111  VAL B N     1 
ATOM   4194  C CA    . VAL B 1 111 ? -8.080   -40.771  -25.359 1.00 28.72  ? 111  VAL B CA    1 
ATOM   4195  C C     . VAL B 1 111 ? -7.693   -39.468  -24.630 1.00 30.07  ? 111  VAL B C     1 
ATOM   4196  O O     . VAL B 1 111 ? -7.091   -39.512  -23.555 1.00 31.10  ? 111  VAL B O     1 
ATOM   4197  C CB    . VAL B 1 111 ? -7.164   -41.106  -26.545 1.00 27.31  ? 111  VAL B CB    1 
ATOM   4198  C CG1   . VAL B 1 111 ? -5.768   -40.632  -26.326 1.00 30.22  ? 111  VAL B CG1   1 
ATOM   4199  C CG2   . VAL B 1 111 ? -7.191   -42.601  -26.863 1.00 28.73  ? 111  VAL B CG2   1 
ATOM   4200  N N     . ALA B 1 112 ? -8.058   -38.307  -25.188 1.00 22.40  ? 112  ALA B N     1 
ATOM   4201  C CA    . ALA B 1 112 ? -7.735   -37.041  -24.561 1.00 24.21  ? 112  ALA B CA    1 
ATOM   4202  C C     . ALA B 1 112 ? -8.475   -36.925  -23.218 1.00 28.39  ? 112  ALA B C     1 
ATOM   4203  O O     . ALA B 1 112 ? -7.890   -36.541  -22.197 1.00 32.92  ? 112  ALA B O     1 
ATOM   4204  C CB    . ALA B 1 112 ? -8.059   -35.878  -25.513 1.00 20.23  ? 112  ALA B CB    1 
ATOM   4205  N N     . ALA B 1 113 ? -9.760   -37.320  -23.203 1.00 28.30  ? 113  ALA B N     1 
ATOM   4206  C CA    . ALA B 1 113 ? -10.562  -37.249  -21.992 1.00 25.56  ? 113  ALA B CA    1 
ATOM   4207  C C     . ALA B 1 113 ? -9.969   -38.152  -20.905 1.00 26.04  ? 113  ALA B C     1 
ATOM   4208  O O     . ALA B 1 113 ? -9.865   -37.726  -19.751 1.00 26.73  ? 113  ALA B O     1 
ATOM   4209  C CB    . ALA B 1 113 ? -12.008  -37.563  -22.299 1.00 22.47  ? 113  ALA B CB    1 
ATOM   4210  N N     . CYS B 1 114 ? -9.529   -39.363  -21.285 1.00 24.22  ? 114  CYS B N     1 
ATOM   4211  C CA    . CYS B 1 114 ? -8.945   -40.279  -20.321 1.00 29.51  ? 114  CYS B CA    1 
ATOM   4212  C C     . CYS B 1 114 ? -7.677   -39.688  -19.712 1.00 39.27  ? 114  CYS B C     1 
ATOM   4213  O O     . CYS B 1 114 ? -7.478   -39.778  -18.491 1.00 34.43  ? 114  CYS B O     1 
ATOM   4214  C CB    . CYS B 1 114 ? -8.599   -41.640  -20.913 1.00 26.17  ? 114  CYS B CB    1 
ATOM   4215  S SG    . CYS B 1 114 ? -10.074  -42.649  -21.264 1.00 27.20  ? 114  CYS B SG    1 
ATOM   4216  N N     . ARG B 1 115 ? -6.832   -39.085  -20.563 1.00 37.52  ? 115  ARG B N     1 
ATOM   4217  C CA    . ARG B 1 115 ? -5.552   -38.584  -20.081 1.00 36.14  ? 115  ARG B CA    1 
ATOM   4218  C C     . ARG B 1 115 ? -5.763   -37.448  -19.093 1.00 30.69  ? 115  ARG B C     1 
ATOM   4219  O O     . ARG B 1 115 ? -5.052   -37.374  -18.111 1.00 32.70  ? 115  ARG B O     1 
ATOM   4220  C CB    . ARG B 1 115 ? -4.612   -38.086  -21.183 1.00 39.31  ? 115  ARG B CB    1 
ATOM   4221  C CG    . ARG B 1 115 ? -3.942   -39.343  -21.701 1.00 44.73  ? 115  ARG B CG    1 
ATOM   4222  C CD    . ARG B 1 115 ? -3.362   -39.041  -23.040 1.00 49.41  ? 115  ARG B CD    1 
ATOM   4223  N NE    . ARG B 1 115 ? -3.067   -40.342  -23.650 1.00 50.89  ? 115  ARG B NE    1 
ATOM   4224  C CZ    . ARG B 1 115 ? -2.793   -40.457  -24.925 1.00 51.19  ? 115  ARG B CZ    1 
ATOM   4225  N NH1   . ARG B 1 115 ? -2.884   -39.394  -25.724 1.00 48.34  ? 115  ARG B NH1   1 
ATOM   4226  N NH2   . ARG B 1 115 ? -2.453   -41.646  -25.384 1.00 49.24  ? 115  ARG B NH2   1 
ATOM   4227  N N     . GLU B 1 116 ? -6.742   -36.584  -19.350 1.00 30.47  ? 116  GLU B N     1 
ATOM   4228  C CA    . GLU B 1 116 ? -6.956   -35.480  -18.440 1.00 34.47  ? 116  GLU B CA    1 
ATOM   4229  C C     . GLU B 1 116 ? -7.446   -35.965  -17.079 1.00 38.23  ? 116  GLU B C     1 
ATOM   4230  O O     . GLU B 1 116 ? -7.281   -35.232  -16.115 1.00 38.35  ? 116  GLU B O     1 
ATOM   4231  C CB    . GLU B 1 116 ? -7.593   -34.240  -19.065 1.00 40.82  ? 116  GLU B CB    1 
ATOM   4232  C CG    . GLU B 1 116 ? -9.089   -34.331  -19.305 1.00 65.96  ? 116  GLU B CG    1 
ATOM   4233  C CD    . GLU B 1 116 ? -9.476   -33.287  -20.342 1.00 77.74  ? 116  GLU B CD    1 
ATOM   4234  O OE1   . GLU B 1 116 ? -8.532   -32.755  -20.978 1.00 74.64  ? 116  GLU B OE1   1 
ATOM   4235  O OE2   . GLU B 1 116 ? -10.696  -32.998  -20.494 1.00 80.67  ? 116  GLU B OE2   1 
ATOM   4236  N N     . GLU B 1 117 ? -8.006   -37.184  -16.984 1.00 37.78  ? 117  GLU B N     1 
ATOM   4237  C CA    . GLU B 1 117 ? -8.518   -37.689  -15.711 1.00 31.16  ? 117  GLU B CA    1 
ATOM   4238  C C     . GLU B 1 117 ? -7.579   -38.732  -15.117 1.00 28.85  ? 117  GLU B C     1 
ATOM   4239  O O     . GLU B 1 117 ? -7.934   -39.407  -14.152 1.00 28.24  ? 117  GLU B O     1 
ATOM   4240  C CB    . GLU B 1 117 ? -9.923   -38.287  -15.863 1.00 31.28  ? 117  GLU B CB    1 
ATOM   4241  C CG    . GLU B 1 117 ? -10.991  -37.225  -16.145 1.00 37.13  ? 117  GLU B CG    1 
ATOM   4242  C CD    . GLU B 1 117 ? -11.487  -36.420  -14.937 1.00 40.55  ? 117  GLU B CD    1 
ATOM   4243  O OE1   . GLU B 1 117 ? -10.844  -36.410  -13.866 1.00 48.42  ? 117  GLU B OE1   1 
ATOM   4244  O OE2   . GLU B 1 117 ? -12.577  -35.847  -15.032 1.00 52.69  ? 117  GLU B OE2   1 
ATOM   4245  N N     . ASP B 1 118 ? -6.406   -38.897  -15.727 1.00 27.43  ? 118  ASP B N     1 
ATOM   4246  C CA    . ASP B 1 118 ? -5.469   -39.941  -15.319 1.00 34.55  ? 118  ASP B CA    1 
ATOM   4247  C C     . ASP B 1 118 ? -6.063   -41.360  -15.422 1.00 31.40  ? 118  ASP B C     1 
ATOM   4248  O O     . ASP B 1 118 ? -5.766   -42.226  -14.608 1.00 28.49  ? 118  ASP B O     1 
ATOM   4249  C CB    . ASP B 1 118 ? -4.765   -39.563  -14.022 1.00 40.68  ? 118  ASP B CB    1 
ATOM   4250  C CG    . ASP B 1 118 ? -3.464   -40.327  -13.759 1.00 66.31  ? 118  ASP B CG    1 
ATOM   4251  O OD1   . ASP B 1 118 ? -2.663   -40.520  -14.721 1.00 75.76  ? 118  ASP B OD1   1 
ATOM   4252  O OD2   . ASP B 1 118 ? -3.235   -40.755  -12.596 1.00 79.98  ? 118  ASP B OD2   1 
ATOM   4253  N N     . LEU B 1 119 ? -6.876   -41.626  -16.451 1.00 28.36  ? 119  LEU B N     1 
ATOM   4254  C CA    . LEU B 1 119 ? -7.380   -42.980  -16.677 1.00 24.16  ? 119  LEU B CA    1 
ATOM   4255  C C     . LEU B 1 119 ? -6.641   -43.603  -17.847 1.00 23.31  ? 119  LEU B C     1 
ATOM   4256  O O     . LEU B 1 119 ? -6.331   -42.903  -18.805 1.00 27.12  ? 119  LEU B O     1 
ATOM   4257  C CB    . LEU B 1 119 ? -8.863   -42.865  -17.021 1.00 23.56  ? 119  LEU B CB    1 
ATOM   4258  C CG    . LEU B 1 119 ? -9.739   -42.164  -15.976 1.00 26.63  ? 119  LEU B CG    1 
ATOM   4259  C CD1   . LEU B 1 119 ? -11.153  -42.039  -16.497 1.00 25.63  ? 119  LEU B CD1   1 
ATOM   4260  C CD2   . LEU B 1 119 ? -9.712   -42.986  -14.699 1.00 26.98  ? 119  LEU B CD2   1 
ATOM   4261  N N     . LEU B 1 120 ? -6.385   -44.913  -17.797 1.00 20.22  ? 120  LEU B N     1 
ATOM   4262  C CA    . LEU B 1 120 ? -5.845   -45.588  -18.966 1.00 21.70  ? 120  LEU B CA    1 
ATOM   4263  C C     . LEU B 1 120 ? -6.949   -45.866  -20.000 1.00 24.66  ? 120  LEU B C     1 
ATOM   4264  O O     . LEU B 1 120 ? -7.973   -46.470  -19.683 1.00 24.50  ? 120  LEU B O     1 
ATOM   4265  C CB    . LEU B 1 120 ? -5.125   -46.866  -18.554 1.00 22.95  ? 120  LEU B CB    1 
ATOM   4266  C CG    . LEU B 1 120 ? -3.842   -46.638  -17.729 1.00 27.59  ? 120  LEU B CG    1 
ATOM   4267  C CD1   . LEU B 1 120 ? -3.148   -47.963  -17.502 1.00 22.95  ? 120  LEU B CD1   1 
ATOM   4268  C CD2   . LEU B 1 120 ? -2.856   -45.638  -18.388 1.00 26.14  ? 120  LEU B CD2   1 
ATOM   4269  N N     . PRO B 1 121 ? -6.768   -45.458  -21.286 1.00 25.47  ? 121  PRO B N     1 
ATOM   4270  C CA    . PRO B 1 121 ? -7.708   -45.815  -22.351 1.00 22.35  ? 121  PRO B CA    1 
ATOM   4271  C C     . PRO B 1 121 ? -7.412   -47.197  -22.925 1.00 22.15  ? 121  PRO B C     1 
ATOM   4272  O O     . PRO B 1 121 ? -6.265   -47.523  -23.242 1.00 26.80  ? 121  PRO B O     1 
ATOM   4273  C CB    . PRO B 1 121 ? -7.499   -44.700  -23.386 1.00 21.93  ? 121  PRO B CB    1 
ATOM   4274  C CG    . PRO B 1 121 ? -5.978   -44.453  -23.240 1.00 22.29  ? 121  PRO B CG    1 
ATOM   4275  C CD    . PRO B 1 121 ? -5.657   -44.602  -21.769 1.00 21.96  ? 121  PRO B CD    1 
ATOM   4276  N N     . PHE B 1 122 ? -8.446   -48.039  -23.005 1.00 22.11  ? 122  PHE B N     1 
ATOM   4277  C CA    . PHE B 1 122 ? -8.297   -49.372  -23.569 1.00 19.72  ? 122  PHE B CA    1 
ATOM   4278  C C     . PHE B 1 122 ? -9.236   -49.474  -24.765 1.00 19.87  ? 122  PHE B C     1 
ATOM   4279  O O     . PHE B 1 122 ? -10.333  -48.910  -24.741 1.00 23.30  ? 122  PHE B O     1 
ATOM   4280  C CB    . PHE B 1 122 ? -8.685   -50.481  -22.600 1.00 21.90  ? 122  PHE B CB    1 
ATOM   4281  C CG    . PHE B 1 122 ? -7.630   -50.943  -21.610 1.00 23.51  ? 122  PHE B CG    1 
ATOM   4282  C CD1   . PHE B 1 122 ? -6.986   -50.035  -20.778 1.00 21.09  ? 122  PHE B CD1   1 
ATOM   4283  C CD2   . PHE B 1 122 ? -7.295   -52.293  -21.511 1.00 19.56  ? 122  PHE B CD2   1 
ATOM   4284  C CE1   . PHE B 1 122 ? -6.034   -50.471  -19.856 1.00 19.23  ? 122  PHE B CE1   1 
ATOM   4285  C CE2   . PHE B 1 122 ? -6.361   -52.728  -20.579 1.00 19.41  ? 122  PHE B CE2   1 
ATOM   4286  C CZ    . PHE B 1 122 ? -5.720   -51.809  -19.768 1.00 19.75  ? 122  PHE B CZ    1 
ATOM   4287  N N     . PHE B 1 123 ? -8.798   -50.205  -25.787 1.00 20.41  ? 123  PHE B N     1 
ATOM   4288  C CA    . PHE B 1 123 ? -9.558   -50.308  -27.026 1.00 21.95  ? 123  PHE B CA    1 
ATOM   4289  C C     . PHE B 1 123 ? -10.068  -51.735  -27.180 1.00 22.51  ? 123  PHE B C     1 
ATOM   4290  O O     . PHE B 1 123 ? -9.279   -52.679  -27.314 1.00 24.60  ? 123  PHE B O     1 
ATOM   4291  C CB    . PHE B 1 123 ? -8.657   -49.992  -28.221 1.00 20.72  ? 123  PHE B CB    1 
ATOM   4292  C CG    . PHE B 1 123 ? -8.091   -48.573  -28.241 1.00 22.39  ? 123  PHE B CG    1 
ATOM   4293  C CD1   . PHE B 1 123 ? -8.806   -47.500  -27.688 1.00 24.15  ? 123  PHE B CD1   1 
ATOM   4294  C CD2   . PHE B 1 123 ? -6.852   -48.305  -28.836 1.00 19.87  ? 123  PHE B CD2   1 
ATOM   4295  C CE1   . PHE B 1 123 ? -8.284   -46.189  -27.733 1.00 21.07  ? 123  PHE B CE1   1 
ATOM   4296  C CE2   . PHE B 1 123 ? -6.349   -47.015  -28.886 1.00 18.14  ? 123  PHE B CE2   1 
ATOM   4297  C CZ    . PHE B 1 123 ? -7.061   -45.949  -28.336 1.00 20.27  ? 123  PHE B CZ    1 
ATOM   4298  N N     . TYR B 1 124 ? -11.392  -51.888  -27.157 1.00 20.27  ? 124  TYR B N     1 
ATOM   4299  C CA    . TYR B 1 124 ? -11.984  -53.169  -27.496 1.00 19.63  ? 124  TYR B CA    1 
ATOM   4300  C C     . TYR B 1 124 ? -12.008  -53.273  -29.020 1.00 20.46  ? 124  TYR B C     1 
ATOM   4301  O O     . TYR B 1 124 ? -12.355  -52.306  -29.709 1.00 21.54  ? 124  TYR B O     1 
ATOM   4302  C CB    . TYR B 1 124 ? -13.398  -53.235  -26.900 1.00 18.04  ? 124  TYR B CB    1 
ATOM   4303  C CG    . TYR B 1 124 ? -14.278  -54.354  -27.464 1.00 20.61  ? 124  TYR B CG    1 
ATOM   4304  C CD1   . TYR B 1 124 ? -14.777  -54.293  -28.773 1.00 22.67  ? 124  TYR B CD1   1 
ATOM   4305  C CD2   . TYR B 1 124 ? -14.626  -55.460  -26.690 1.00 20.96  ? 124  TYR B CD2   1 
ATOM   4306  C CE1   . TYR B 1 124 ? -15.573  -55.304  -29.299 1.00 24.43  ? 124  TYR B CE1   1 
ATOM   4307  C CE2   . TYR B 1 124 ? -15.410  -56.484  -27.201 1.00 21.25  ? 124  TYR B CE2   1 
ATOM   4308  C CZ    . TYR B 1 124 ? -15.883  -56.406  -28.512 1.00 25.80  ? 124  TYR B CZ    1 
ATOM   4309  O OH    . TYR B 1 124 ? -16.657  -57.400  -29.052 1.00 24.95  ? 124  TYR B OH    1 
ATOM   4310  N N     . MET B 1 125 ? -11.670  -54.457  -29.536 1.00 22.84  ? 125  MET B N     1 
ATOM   4311  C CA    . MET B 1 125 ? -11.708  -54.705  -30.972 1.00 23.08  ? 125  MET B CA    1 
ATOM   4312  C C     . MET B 1 125 ? -12.289  -56.097  -31.215 1.00 23.55  ? 125  MET B C     1 
ATOM   4313  O O     . MET B 1 125 ? -11.774  -57.090  -30.677 1.00 21.81  ? 125  MET B O     1 
ATOM   4314  C CB    . MET B 1 125 ? -10.291  -54.606  -31.562 1.00 25.75  ? 125  MET B CB    1 
ATOM   4315  C CG    . MET B 1 125 ? -10.159  -55.154  -32.985 1.00 25.21  ? 125  MET B CG    1 
ATOM   4316  S SD    . MET B 1 125 ? -11.060  -54.213  -34.244 1.00 28.01  ? 125  MET B SD    1 
ATOM   4317  C CE    . MET B 1 125 ? -10.167  -52.636  -34.175 1.00 21.65  ? 125  MET B CE    1 
ATOM   4318  N N     . ALA B 1 126 ? -13.384  -56.171  -31.995 1.00 23.61  ? 126  ALA B N     1 
ATOM   4319  C CA    . ALA B 1 126 ? -13.948  -57.482  -32.332 1.00 25.06  ? 126  ALA B CA    1 
ATOM   4320  C C     . ALA B 1 126 ? -13.138  -58.131  -33.464 1.00 25.57  ? 126  ALA B C     1 
ATOM   4321  O O     . ALA B 1 126 ? -12.870  -57.504  -34.490 1.00 27.07  ? 126  ALA B O     1 
ATOM   4322  C CB    . ALA B 1 126 ? -15.415  -57.346  -32.717 1.00 22.52  ? 126  ALA B CB    1 
ATOM   4323  N N     . THR B 1 127 ? -12.769  -59.390  -33.295 1.00 24.99  ? 127  THR B N     1 
ATOM   4324  C CA    . THR B 1 127 ? -12.010  -60.061  -34.341 1.00 27.69  ? 127  THR B CA    1 
ATOM   4325  C C     . THR B 1 127 ? -12.951  -60.863  -35.239 1.00 30.72  ? 127  THR B C     1 
ATOM   4326  O O     . THR B 1 127 ? -12.578  -61.197  -36.360 1.00 35.30  ? 127  THR B O     1 
ATOM   4327  C CB    . THR B 1 127 ? -10.890  -60.918  -33.755 1.00 24.00  ? 127  THR B CB    1 
ATOM   4328  O OG1   . THR B 1 127 ? -11.580  -61.956  -33.057 1.00 23.38  ? 127  THR B OG1   1 
ATOM   4329  C CG2   . THR B 1 127 ? -9.985   -60.118  -32.828 1.00 20.47  ? 127  THR B CG2   1 
ATOM   4330  N N     . TYR B 1 128 ? -14.163  -61.157  -34.756 1.00 28.43  ? 128  TYR B N     1 
ATOM   4331  C CA    . TYR B 1 128 ? -15.201  -61.723  -35.597 1.00 28.71  ? 128  TYR B CA    1 
ATOM   4332  C C     . TYR B 1 128 ? -16.013  -60.565  -36.174 1.00 29.26  ? 128  TYR B C     1 
ATOM   4333  O O     . TYR B 1 128 ? -16.645  -59.816  -35.423 1.00 32.08  ? 128  TYR B O     1 
ATOM   4334  C CB    . TYR B 1 128 ? -16.042  -62.582  -34.653 1.00 28.23  ? 128  TYR B CB    1 
ATOM   4335  C CG    . TYR B 1 128 ? -17.322  -63.209  -35.198 1.00 32.02  ? 128  TYR B CG    1 
ATOM   4336  C CD1   . TYR B 1 128 ? -17.460  -63.552  -36.548 1.00 32.46  ? 128  TYR B CD1   1 
ATOM   4337  C CD2   . TYR B 1 128 ? -18.391  -63.506  -34.341 1.00 32.59  ? 128  TYR B CD2   1 
ATOM   4338  C CE1   . TYR B 1 128 ? -18.611  -64.171  -37.020 1.00 31.32  ? 128  TYR B CE1   1 
ATOM   4339  C CE2   . TYR B 1 128 ? -19.542  -64.126  -34.801 1.00 30.20  ? 128  TYR B CE2   1 
ATOM   4340  C CZ    . TYR B 1 128 ? -19.652  -64.459  -36.146 1.00 33.29  ? 128  TYR B CZ    1 
ATOM   4341  O OH    . TYR B 1 128 ? -20.778  -65.060  -36.648 1.00 35.00  ? 128  TYR B OH    1 
ATOM   4342  N N     . ASP B 1 129 ? -15.996  -60.432  -37.507 1.00 26.35  ? 129  ASP B N     1 
ATOM   4343  C CA    . ASP B 1 129 ? -16.475  -59.227  -38.172 1.00 27.82  ? 129  ASP B CA    1 
ATOM   4344  C C     . ASP B 1 129 ? -17.574  -59.611  -39.171 1.00 29.85  ? 129  ASP B C     1 
ATOM   4345  O O     . ASP B 1 129 ? -17.332  -60.498  -40.010 1.00 33.30  ? 129  ASP B O     1 
ATOM   4346  C CB    . ASP B 1 129 ? -15.284  -58.527  -38.814 1.00 27.07  ? 129  ASP B CB    1 
ATOM   4347  C CG    . ASP B 1 129 ? -15.594  -57.174  -39.446 1.00 31.66  ? 129  ASP B CG    1 
ATOM   4348  O OD1   . ASP B 1 129 ? -16.580  -57.094  -40.247 1.00 31.30  ? 129  ASP B OD1   1 
ATOM   4349  O OD2   . ASP B 1 129 ? -14.815  -56.213  -39.184 1.00 29.87  ? 129  ASP B OD2   1 
ATOM   4350  N N     . TRP B 1 130 ? -18.746  -58.959  -39.086 1.00 30.78  ? 130  TRP B N     1 
ATOM   4351  C CA    . TRP B 1 130 ? -19.883  -59.293  -39.944 1.00 25.74  ? 130  TRP B CA    1 
ATOM   4352  C C     . TRP B 1 130 ? -19.904  -58.389  -41.181 1.00 24.66  ? 130  TRP B C     1 
ATOM   4353  O O     . TRP B 1 130 ? -20.715  -58.616  -42.061 1.00 23.48  ? 130  TRP B O     1 
ATOM   4354  C CB    . TRP B 1 130 ? -21.231  -59.137  -39.216 1.00 23.23  ? 130  TRP B CB    1 
ATOM   4355  C CG    . TRP B 1 130 ? -21.375  -59.957  -37.969 1.00 27.13  ? 130  TRP B CG    1 
ATOM   4356  C CD1   . TRP B 1 130 ? -20.721  -61.124  -37.687 1.00 32.23  ? 130  TRP B CD1   1 
ATOM   4357  C CD2   . TRP B 1 130 ? -22.184  -59.664  -36.801 1.00 27.71  ? 130  TRP B CD2   1 
ATOM   4358  N NE1   . TRP B 1 130 ? -21.103  -61.618  -36.460 1.00 26.82  ? 130  TRP B NE1   1 
ATOM   4359  C CE2   . TRP B 1 130 ? -21.982  -60.728  -35.881 1.00 27.80  ? 130  TRP B CE2   1 
ATOM   4360  C CE3   . TRP B 1 130 ? -23.050  -58.618  -36.443 1.00 24.09  ? 130  TRP B CE3   1 
ATOM   4361  C CZ2   . TRP B 1 130 ? -22.599  -60.762  -34.626 1.00 24.47  ? 130  TRP B CZ2   1 
ATOM   4362  C CZ3   . TRP B 1 130 ? -23.659  -58.665  -35.203 1.00 23.70  ? 130  TRP B CZ3   1 
ATOM   4363  C CH2   . TRP B 1 130 ? -23.433  -59.711  -34.293 1.00 26.00  ? 130  TRP B CH2   1 
ATOM   4364  N N     . HIS B 1 131 ? -19.086  -57.335  -41.203 1.00 23.17  ? 131  HIS B N     1 
ATOM   4365  C CA    . HIS B 1 131 ? -19.208  -56.351  -42.262 1.00 24.46  ? 131  HIS B CA    1 
ATOM   4366  C C     . HIS B 1 131 ? -18.358  -56.716  -43.496 1.00 31.01  ? 131  HIS B C     1 
ATOM   4367  O O     . HIS B 1 131 ? -18.877  -56.704  -44.601 1.00 32.08  ? 131  HIS B O     1 
ATOM   4368  C CB    . HIS B 1 131 ? -18.757  -54.981  -41.774 1.00 22.29  ? 131  HIS B CB    1 
ATOM   4369  C CG    . HIS B 1 131 ? -18.738  -53.980  -42.873 1.00 25.40  ? 131  HIS B CG    1 
ATOM   4370  N ND1   . HIS B 1 131 ? -19.911  -53.544  -43.478 1.00 23.80  ? 131  HIS B ND1   1 
ATOM   4371  C CD2   . HIS B 1 131 ? -17.690  -53.307  -43.466 1.00 24.71  ? 131  HIS B CD2   1 
ATOM   4372  C CE1   . HIS B 1 131 ? -19.587  -52.628  -44.404 1.00 25.14  ? 131  HIS B CE1   1 
ATOM   4373  N NE2   . HIS B 1 131 ? -18.249  -52.465  -44.418 1.00 25.06  ? 131  HIS B NE2   1 
ATOM   4374  N N     . THR B 1 132 ? -17.057  -56.993  -43.329 1.00 29.89  ? 132  THR B N     1 
ATOM   4375  C CA    . THR B 1 132 ? -16.162  -57.243  -44.452 1.00 33.21  ? 132  THR B CA    1 
ATOM   4376  C C     . THR B 1 132 ? -16.330  -58.662  -45.001 1.00 32.40  ? 132  THR B C     1 
ATOM   4377  O O     . THR B 1 132 ? -16.198  -59.640  -44.279 1.00 31.31  ? 132  THR B O     1 
ATOM   4378  C CB    . THR B 1 132 ? -14.704  -56.960  -44.093 1.00 36.99  ? 132  THR B CB    1 
ATOM   4379  O OG1   . THR B 1 132 ? -13.947  -57.481  -45.191 1.00 37.58  ? 132  THR B OG1   1 
ATOM   4380  C CG2   . THR B 1 132 ? -14.250  -57.716  -42.859 1.00 30.70  ? 132  THR B CG2   1 
ATOM   4381  N N     . PRO B 1 133 ? -16.581  -58.814  -46.320 1.00 37.51  ? 133  PRO B N     1 
ATOM   4382  C CA    . PRO B 1 133 ? -16.621  -60.156  -46.922 1.00 37.78  ? 133  PRO B CA    1 
ATOM   4383  C C     . PRO B 1 133 ? -15.288  -60.914  -46.812 1.00 34.03  ? 133  PRO B C     1 
ATOM   4384  O O     . PRO B 1 133 ? -15.264  -62.140  -46.908 1.00 30.60  ? 133  PRO B O     1 
ATOM   4385  C CB    . PRO B 1 133 ? -17.086  -59.920  -48.367 1.00 34.90  ? 133  PRO B CB    1 
ATOM   4386  C CG    . PRO B 1 133 ? -16.846  -58.424  -48.620 1.00 35.67  ? 133  PRO B CG    1 
ATOM   4387  C CD    . PRO B 1 133 ? -16.775  -57.698  -47.283 1.00 31.77  ? 133  PRO B CD    1 
ATOM   4388  N N     . LEU B 1 134 ? -14.187  -60.194  -46.536 1.00 33.09  ? 134  LEU B N     1 
ATOM   4389  C CA    . LEU B 1 134 ? -12.896  -60.866  -46.363 1.00 32.42  ? 134  LEU B CA    1 
ATOM   4390  C C     . LEU B 1 134 ? -12.998  -61.972  -45.316 1.00 31.74  ? 134  LEU B C     1 
ATOM   4391  O O     . LEU B 1 134 ? -12.331  -63.003  -45.429 1.00 39.99  ? 134  LEU B O     1 
ATOM   4392  C CB    . LEU B 1 134 ? -11.726  -59.937  -46.054 1.00 28.72  ? 134  LEU B CB    1 
ATOM   4393  C CG    . LEU B 1 134 ? -11.478  -58.813  -47.058 1.00 35.70  ? 134  LEU B CG    1 
ATOM   4394  C CD1   . LEU B 1 134 ? -10.409  -57.825  -46.572 1.00 28.56  ? 134  LEU B CD1   1 
ATOM   4395  C CD2   . LEU B 1 134 ? -11.147  -59.383  -48.478 1.00 34.05  ? 134  LEU B CD2   1 
ATOM   4396  N N     . TYR B 1 135 ? -13.830  -61.757  -44.282 1.00 35.30  ? 135  TYR B N     1 
ATOM   4397  C CA    . TYR B 1 135 ? -13.864  -62.662  -43.144 1.00 32.55  ? 135  TYR B CA    1 
ATOM   4398  C C     . TYR B 1 135 ? -14.121  -64.096  -43.592 1.00 39.27  ? 135  TYR B C     1 
ATOM   4399  O O     . TYR B 1 135 ? -13.440  -65.005  -43.158 1.00 45.60  ? 135  TYR B O     1 
ATOM   4400  C CB    . TYR B 1 135 ? -14.832  -62.150  -42.077 1.00 29.49  ? 135  TYR B CB    1 
ATOM   4401  C CG    . TYR B 1 135 ? -14.792  -62.979  -40.808 1.00 30.24  ? 135  TYR B CG    1 
ATOM   4402  C CD1   . TYR B 1 135 ? -13.821  -62.711  -39.832 1.00 31.79  ? 135  TYR B CD1   1 
ATOM   4403  C CD2   . TYR B 1 135 ? -15.696  -64.019  -40.598 1.00 27.57  ? 135  TYR B CD2   1 
ATOM   4404  C CE1   . TYR B 1 135 ? -13.766  -63.475  -38.670 1.00 29.87  ? 135  TYR B CE1   1 
ATOM   4405  C CE2   . TYR B 1 135 ? -15.674  -64.760  -39.414 1.00 28.50  ? 135  TYR B CE2   1 
ATOM   4406  C CZ    . TYR B 1 135 ? -14.690  -64.496  -38.468 1.00 29.89  ? 135  TYR B CZ    1 
ATOM   4407  O OH    . TYR B 1 135 ? -14.574  -65.235  -37.321 1.00 30.25  ? 135  TYR B OH    1 
ATOM   4408  N N     . ASP B 1 136 ? -15.129  -64.317  -44.439 1.00 50.77  ? 136  ASP B N     1 
ATOM   4409  C CA    . ASP B 1 136 ? -15.463  -65.662  -44.892 1.00 53.54  ? 136  ASP B CA    1 
ATOM   4410  C C     . ASP B 1 136 ? -14.792  -66.015  -46.213 1.00 55.91  ? 136  ASP B C     1 
ATOM   4411  O O     . ASP B 1 136 ? -14.526  -67.197  -46.417 1.00 53.81  ? 136  ASP B O     1 
ATOM   4412  C CB    . ASP B 1 136 ? -16.958  -65.916  -44.994 1.00 56.11  ? 136  ASP B CB    1 
ATOM   4413  C CG    . ASP B 1 136 ? -17.700  -65.941  -43.665 1.00 64.77  ? 136  ASP B CG    1 
ATOM   4414  O OD1   . ASP B 1 136 ? -17.189  -66.583  -42.732 1.00 59.81  ? 136  ASP B OD1   1 
ATOM   4415  O OD2   . ASP B 1 136 ? -18.778  -65.301  -43.566 1.00 77.76  ? 136  ASP B OD2   1 
ATOM   4416  N N     . ASP B 1 137 ? -14.507  -65.023  -47.075 1.00 58.58  ? 137  ASP B N     1 
ATOM   4417  C CA    . ASP B 1 137 ? -14.063  -65.267  -48.444 1.00 58.35  ? 137  ASP B CA    1 
ATOM   4418  C C     . ASP B 1 137 ? -12.546  -65.432  -48.568 1.00 58.76  ? 137  ASP B C     1 
ATOM   4419  O O     . ASP B 1 137 ? -12.061  -66.066  -49.492 1.00 63.62  ? 137  ASP B O     1 
ATOM   4420  C CB    . ASP B 1 137 ? -14.349  -64.093  -49.374 1.00 56.01  ? 137  ASP B CB    1 
ATOM   4421  C CG    . ASP B 1 137 ? -15.796  -63.937  -49.797 1.00 62.26  ? 137  ASP B CG    1 
ATOM   4422  O OD1   . ASP B 1 137 ? -16.617  -64.797  -49.367 1.00 62.87  ? 137  ASP B OD1   1 
ATOM   4423  O OD2   . ASP B 1 137 ? -16.064  -62.930  -50.494 1.00 55.59  ? 137  ASP B OD2   1 
ATOM   4424  N N     . ASP B 1 138 ? -11.795  -64.819  -47.649 1.00 57.56  ? 138  ASP B N     1 
ATOM   4425  C CA    . ASP B 1 138 ? -10.354  -64.676  -47.806 1.00 50.86  ? 138  ASP B CA    1 
ATOM   4426  C C     . ASP B 1 138 ? -9.725   -64.365  -46.448 1.00 55.62  ? 138  ASP B C     1 
ATOM   4427  O O     . ASP B 1 138 ? -9.249   -63.248  -46.187 1.00 42.08  ? 138  ASP B O     1 
ATOM   4428  C CB    . ASP B 1 138 ? -10.034  -63.684  -48.907 1.00 42.83  ? 138  ASP B CB    1 
ATOM   4429  C CG    . ASP B 1 138 ? -8.564   -63.581  -49.313 1.00 57.74  ? 138  ASP B CG    1 
ATOM   4430  O OD1   . ASP B 1 138 ? -7.718   -64.365  -48.757 1.00 61.87  ? 138  ASP B OD1   1 
ATOM   4431  O OD2   . ASP B 1 138 ? -8.268   -62.700  -50.174 1.00 50.33  ? 138  ASP B OD2   1 
ATOM   4432  N N     . PHE B 1 139 ? -9.705   -65.395  -45.599 1.00 52.24  ? 139  PHE B N     1 
ATOM   4433  C CA    . PHE B 1 139 ? -9.348   -65.224  -44.208 1.00 52.44  ? 139  PHE B CA    1 
ATOM   4434  C C     . PHE B 1 139 ? -7.955   -64.601  -44.081 1.00 64.28  ? 139  PHE B C     1 
ATOM   4435  O O     . PHE B 1 139 ? -7.768   -63.674  -43.302 1.00 58.73  ? 139  PHE B O     1 
ATOM   4436  C CB    . PHE B 1 139 ? -9.594   -66.493  -43.409 1.00 43.69  ? 139  PHE B CB    1 
ATOM   4437  C CG    . PHE B 1 139 ? -9.442   -66.269  -41.915 1.00 60.73  ? 139  PHE B CG    1 
ATOM   4438  C CD1   . PHE B 1 139 ? -10.400  -65.544  -41.213 1.00 62.73  ? 139  PHE B CD1   1 
ATOM   4439  C CD2   . PHE B 1 139 ? -8.364   -66.784  -41.205 1.00 61.46  ? 139  PHE B CD2   1 
ATOM   4440  C CE1   . PHE B 1 139 ? -10.338  -65.388  -39.834 1.00 60.45  ? 139  PHE B CE1   1 
ATOM   4441  C CE2   . PHE B 1 139 ? -8.287   -66.629  -39.826 1.00 64.09  ? 139  PHE B CE2   1 
ATOM   4442  C CZ    . PHE B 1 139 ? -9.267   -65.927  -39.147 1.00 62.38  ? 139  PHE B CZ    1 
ATOM   4443  N N     . PRO B 1 140 ? -6.927   -65.058  -44.835 1.00 66.77  ? 140  PRO B N     1 
ATOM   4444  C CA    . PRO B 1 140 ? -5.606   -64.443  -44.773 1.00 59.62  ? 140  PRO B CA    1 
ATOM   4445  C C     . PRO B 1 140 ? -5.633   -62.934  -44.992 1.00 55.95  ? 140  PRO B C     1 
ATOM   4446  O O     . PRO B 1 140 ? -4.944   -62.192  -44.307 1.00 70.10  ? 140  PRO B O     1 
ATOM   4447  C CB    . PRO B 1 140 ? -4.751   -65.248  -45.778 1.00 61.09  ? 140  PRO B CB    1 
ATOM   4448  C CG    . PRO B 1 140 ? -5.478   -66.591  -45.763 1.00 72.85  ? 140  PRO B CG    1 
ATOM   4449  C CD    . PRO B 1 140 ? -6.952   -66.209  -45.753 1.00 75.02  ? 140  PRO B CD    1 
ATOM   4450  N N     . ALA B 1 141 ? -6.444   -62.483  -45.949 1.00 53.21  ? 141  ALA B N     1 
ATOM   4451  C CA    . ALA B 1 141 ? -6.557   -61.059  -46.233 1.00 44.15  ? 141  ALA B CA    1 
ATOM   4452  C C     . ALA B 1 141 ? -7.354   -60.355  -45.121 1.00 39.52  ? 141  ALA B C     1 
ATOM   4453  O O     . ALA B 1 141 ? -7.113   -59.182  -44.853 1.00 33.39  ? 141  ALA B O     1 
ATOM   4454  C CB    . ALA B 1 141 ? -7.160   -60.840  -47.602 1.00 40.59  ? 141  ALA B CB    1 
ATOM   4455  N N     . TYR B 1 142 ? -8.291   -61.078  -44.485 1.00 33.15  ? 142  TYR B N     1 
ATOM   4456  C CA    . TYR B 1 142 ? -9.009   -60.599  -43.313 1.00 38.77  ? 142  TYR B CA    1 
ATOM   4457  C C     . TYR B 1 142 ? -8.009   -60.279  -42.194 1.00 43.07  ? 142  TYR B C     1 
ATOM   4458  O O     . TYR B 1 142 ? -8.060   -59.195  -41.603 1.00 36.08  ? 142  TYR B O     1 
ATOM   4459  C CB    . TYR B 1 142 ? -10.206  -61.439  -42.846 1.00 29.57  ? 142  TYR B CB    1 
ATOM   4460  C CG    . TYR B 1 142 ? -10.727  -60.877  -41.535 1.00 35.79  ? 142  TYR B CG    1 
ATOM   4461  C CD1   . TYR B 1 142 ? -11.501  -59.708  -41.502 1.00 33.51  ? 142  TYR B CD1   1 
ATOM   4462  C CD2   . TYR B 1 142 ? -10.393  -61.472  -40.320 1.00 37.22  ? 142  TYR B CD2   1 
ATOM   4463  C CE1   . TYR B 1 142 ? -11.931  -59.159  -40.299 1.00 36.97  ? 142  TYR B CE1   1 
ATOM   4464  C CE2   . TYR B 1 142 ? -10.843  -60.933  -39.118 1.00 39.80  ? 142  TYR B CE2   1 
ATOM   4465  C CZ    . TYR B 1 142 ? -11.602  -59.773  -39.105 1.00 37.71  ? 142  TYR B CZ    1 
ATOM   4466  O OH    . TYR B 1 142 ? -12.008  -59.241  -37.918 1.00 40.31  ? 142  TYR B OH    1 
ATOM   4467  N N     . LEU B 1 143 ? -7.074   -61.204  -41.941 1.00 38.37  ? 143  LEU B N     1 
ATOM   4468  C CA    . LEU B 1 143 ? -6.051   -61.007  -40.926 1.00 32.16  ? 143  LEU B CA    1 
ATOM   4469  C C     . LEU B 1 143 ? -5.272   -59.733  -41.184 1.00 35.76  ? 143  LEU B C     1 
ATOM   4470  O O     . LEU B 1 143 ? -4.939   -59.031  -40.237 1.00 40.47  ? 143  LEU B O     1 
ATOM   4471  C CB    . LEU B 1 143 ? -5.152   -62.217  -40.745 1.00 35.58  ? 143  LEU B CB    1 
ATOM   4472  C CG    . LEU B 1 143 ? -5.910   -63.479  -40.301 1.00 37.84  ? 143  LEU B CG    1 
ATOM   4473  C CD1   . LEU B 1 143 ? -4.925   -64.615  -40.183 1.00 36.09  ? 143  LEU B CD1   1 
ATOM   4474  C CD2   . LEU B 1 143 ? -6.762   -63.303  -39.044 1.00 36.86  ? 143  LEU B CD2   1 
ATOM   4475  N N     . THR B 1 144 ? -5.030   -59.402  -42.450 1.00 35.51  ? 144  THR B N     1 
ATOM   4476  C CA    . THR B 1 144 ? -4.269   -58.203  -42.783 1.00 34.15  ? 144  THR B CA    1 
ATOM   4477  C C     . THR B 1 144 ? -5.101   -56.971  -42.445 1.00 33.74  ? 144  THR B C     1 
ATOM   4478  O O     . THR B 1 144 ? -4.561   -55.980  -41.964 1.00 33.85  ? 144  THR B O     1 
ATOM   4479  C CB    . THR B 1 144 ? -3.830   -58.189  -44.258 1.00 31.91  ? 144  THR B CB    1 
ATOM   4480  O OG1   . THR B 1 144 ? -2.960   -59.302  -44.333 1.00 32.27  ? 144  THR B OG1   1 
ATOM   4481  C CG2   . THR B 1 144 ? -2.952   -57.003  -44.621 1.00 24.47  ? 144  THR B CG2   1 
ATOM   4482  N N     . TYR B 1 145 ? -6.403   -57.032  -42.741 1.00 36.66  ? 145  TYR B N     1 
ATOM   4483  C CA    . TYR B 1 145 ? -7.335   -55.932  -42.489 1.00 31.76  ? 145  TYR B CA    1 
ATOM   4484  C C     . TYR B 1 145 ? -7.465   -55.713  -40.983 1.00 27.02  ? 145  TYR B C     1 
ATOM   4485  O O     . TYR B 1 145 ? -7.358   -54.574  -40.516 1.00 29.49  ? 145  TYR B O     1 
ATOM   4486  C CB    . TYR B 1 145 ? -8.648   -56.384  -43.122 1.00 28.26  ? 145  TYR B CB    1 
ATOM   4487  C CG    . TYR B 1 145 ? -9.892   -55.542  -42.879 1.00 30.47  ? 145  TYR B CG    1 
ATOM   4488  C CD1   . TYR B 1 145 ? -10.252  -54.534  -43.762 1.00 32.52  ? 145  TYR B CD1   1 
ATOM   4489  C CD2   . TYR B 1 145 ? -10.752  -55.807  -41.812 1.00 27.49  ? 145  TYR B CD2   1 
ATOM   4490  C CE1   . TYR B 1 145 ? -11.427  -53.807  -43.592 1.00 32.21  ? 145  TYR B CE1   1 
ATOM   4491  C CE2   . TYR B 1 145 ? -11.905  -55.070  -41.609 1.00 29.20  ? 145  TYR B CE2   1 
ATOM   4492  C CZ    . TYR B 1 145 ? -12.247  -54.066  -42.504 1.00 34.53  ? 145  TYR B CZ    1 
ATOM   4493  O OH    . TYR B 1 145 ? -13.400  -53.352  -42.322 1.00 34.84  ? 145  TYR B OH    1 
ATOM   4494  N N     . LEU B 1 146 ? -7.642   -56.812  -40.235 1.00 24.25  ? 146  LEU B N     1 
ATOM   4495  C CA    . LEU B 1 146 ? -7.736   -56.750  -38.786 1.00 28.26  ? 146  LEU B CA    1 
ATOM   4496  C C     . LEU B 1 146 ? -6.466   -56.096  -38.232 1.00 33.17  ? 146  LEU B C     1 
ATOM   4497  O O     . LEU B 1 146 ? -6.525   -55.101  -37.502 1.00 32.31  ? 146  LEU B O     1 
ATOM   4498  C CB    . LEU B 1 146 ? -8.006   -58.139  -38.212 1.00 25.99  ? 146  LEU B CB    1 
ATOM   4499  C CG    . LEU B 1 146 ? -7.909   -58.234  -36.687 1.00 30.51  ? 146  LEU B CG    1 
ATOM   4500  C CD1   . LEU B 1 146 ? -8.939   -57.313  -35.999 1.00 25.50  ? 146  LEU B CD1   1 
ATOM   4501  C CD2   . LEU B 1 146 ? -8.143   -59.701  -36.275 1.00 26.28  ? 146  LEU B CD2   1 
ATOM   4502  N N     . GLN B 1 147 ? -5.315   -56.603  -38.672 1.00 32.05  ? 147  GLN B N     1 
ATOM   4503  C CA    . GLN B 1 147 ? -4.031   -56.109  -38.205 1.00 30.80  ? 147  GLN B CA    1 
ATOM   4504  C C     . GLN B 1 147 ? -3.847   -54.636  -38.535 1.00 32.33  ? 147  GLN B C     1 
ATOM   4505  O O     . GLN B 1 147 ? -3.353   -53.863  -37.710 1.00 32.29  ? 147  GLN B O     1 
ATOM   4506  C CB    . GLN B 1 147 ? -2.878   -56.965  -38.715 1.00 34.58  ? 147  GLN B CB    1 
ATOM   4507  C CG    . GLN B 1 147 ? -1.547   -56.469  -38.182 1.00 38.25  ? 147  GLN B CG    1 
ATOM   4508  C CD    . GLN B 1 147 ? -0.419   -57.453  -38.366 1.00 39.53  ? 147  GLN B CD    1 
ATOM   4509  O OE1   . GLN B 1 147 ? -0.544   -58.668  -38.141 1.00 40.03  ? 147  GLN B OE1   1 
ATOM   4510  N NE2   . GLN B 1 147 ? 0.715    -56.897  -38.732 1.00 37.17  ? 147  GLN B NE2   1 
ATOM   4511  N N     . LYS B 1 148 ? -4.258   -54.226  -39.738 1.00 30.15  ? 148  LYS B N     1 
ATOM   4512  C CA    . LYS B 1 148 ? -4.103   -52.833  -40.130 1.00 29.31  ? 148  LYS B CA    1 
ATOM   4513  C C     . LYS B 1 148 ? -4.999   -51.948  -39.256 1.00 27.83  ? 148  LYS B C     1 
ATOM   4514  O O     . LYS B 1 148 ? -4.604   -50.846  -38.868 1.00 29.80  ? 148  LYS B O     1 
ATOM   4515  C CB    . LYS B 1 148 ? -4.422   -52.726  -41.622 1.00 34.89  ? 148  LYS B CB    1 
ATOM   4516  C CG    . LYS B 1 148 ? -4.121   -51.389  -42.235 1.00 51.36  ? 148  LYS B CG    1 
ATOM   4517  C CD    . LYS B 1 148 ? -2.644   -51.410  -42.622 1.00 70.13  ? 148  LYS B CD    1 
ATOM   4518  C CE    . LYS B 1 148 ? -2.189   -50.163  -43.308 1.00 79.88  ? 148  LYS B CE    1 
ATOM   4519  N NZ    . LYS B 1 148 ? -1.938   -49.121  -42.311 1.00 71.08  ? 148  LYS B NZ    1 
ATOM   4520  N N     . SER B 1 149 ? -6.217   -52.421  -38.961 1.00 25.58  ? 149  SER B N     1 
ATOM   4521  C CA    . SER B 1 149 ? -7.142   -51.636  -38.147 1.00 28.77  ? 149  SER B CA    1 
ATOM   4522  C C     . SER B 1 149 ? -6.577   -51.442  -36.736 1.00 28.19  ? 149  SER B C     1 
ATOM   4523  O O     . SER B 1 149 ? -6.711   -50.369  -36.158 1.00 26.94  ? 149  SER B O     1 
ATOM   4524  C CB    . SER B 1 149 ? -8.553   -52.206  -38.130 1.00 26.58  ? 149  SER B CB    1 
ATOM   4525  O OG    . SER B 1 149 ? -8.598   -53.375  -37.331 1.00 25.22  ? 149  SER B OG    1 
ATOM   4526  N N     . VAL B 1 150 ? -5.854   -52.440  -36.224 1.00 27.08  ? 150  VAL B N     1 
ATOM   4527  C CA    . VAL B 1 150 ? -5.206   -52.315  -34.928 1.00 26.05  ? 150  VAL B CA    1 
ATOM   4528  C C     . VAL B 1 150 ? -3.971   -51.419  -35.014 1.00 29.54  ? 150  VAL B C     1 
ATOM   4529  O O     . VAL B 1 150 ? -3.666   -50.669  -34.083 1.00 29.46  ? 150  VAL B O     1 
ATOM   4530  C CB    . VAL B 1 150 ? -4.888   -53.711  -34.366 1.00 28.64  ? 150  VAL B CB    1 
ATOM   4531  C CG1   . VAL B 1 150 ? -4.030   -53.631  -33.107 1.00 27.21  ? 150  VAL B CG1   1 
ATOM   4532  C CG2   . VAL B 1 150 ? -6.180   -54.523  -34.138 1.00 22.23  ? 150  VAL B CG2   1 
ATOM   4533  N N     . GLU B 1 151 ? -3.261   -51.485  -36.144 1.00 30.69  ? 151  GLU B N     1 
ATOM   4534  C CA    . GLU B 1 151 ? -2.090   -50.654  -36.358 1.00 30.44  ? 151  GLU B CA    1 
ATOM   4535  C C     . GLU B 1 151 ? -2.459   -49.173  -36.321 1.00 29.05  ? 151  GLU B C     1 
ATOM   4536  O O     . GLU B 1 151 ? -1.733   -48.377  -35.712 1.00 28.92  ? 151  GLU B O     1 
ATOM   4537  C CB    . GLU B 1 151 ? -1.399   -51.067  -37.653 1.00 32.83  ? 151  GLU B CB    1 
ATOM   4538  C CG    . GLU B 1 151 ? -0.142   -50.259  -37.954 1.00 38.37  ? 151  GLU B CG    1 
ATOM   4539  C CD    . GLU B 1 151 ? 0.336    -50.357  -39.406 1.00 55.45  ? 151  GLU B CD    1 
ATOM   4540  O OE1   . GLU B 1 151 ? 0.162    -51.448  -40.032 1.00 51.37  ? 151  GLU B OE1   1 
ATOM   4541  O OE2   . GLU B 1 151 ? 0.935    -49.353  -39.876 1.00 60.48  ? 151  GLU B OE2   1 
ATOM   4542  N N     . VAL B 1 152 ? -3.590   -48.794  -36.932 1.00 26.16  ? 152  VAL B N     1 
ATOM   4543  C CA    . VAL B 1 152 ? -4.027   -47.405  -36.855 1.00 27.79  ? 152  VAL B CA    1 
ATOM   4544  C C     . VAL B 1 152 ? -4.182   -46.987  -35.390 1.00 29.13  ? 152  VAL B C     1 
ATOM   4545  O O     . VAL B 1 152 ? -3.776   -45.875  -35.028 1.00 30.14  ? 152  VAL B O     1 
ATOM   4546  C CB    . VAL B 1 152 ? -5.348   -47.183  -37.631 1.00 30.32  ? 152  VAL B CB    1 
ATOM   4547  C CG1   . VAL B 1 152 ? -5.975   -45.804  -37.360 1.00 26.00  ? 152  VAL B CG1   1 
ATOM   4548  C CG2   . VAL B 1 152 ? -5.198   -47.451  -39.128 1.00 24.48  ? 152  VAL B CG2   1 
ATOM   4549  N N     . LEU B 1 153 ? -4.767   -47.869  -34.553 1.00 25.39  ? 153  LEU B N     1 
ATOM   4550  C CA    . LEU B 1 153 ? -5.012   -47.565  -33.156 1.00 26.66  ? 153  LEU B CA    1 
ATOM   4551  C C     . LEU B 1 153 ? -3.676   -47.429  -32.430 1.00 28.99  ? 153  LEU B C     1 
ATOM   4552  O O     . LEU B 1 153 ? -3.568   -46.618  -31.510 1.00 24.17  ? 153  LEU B O     1 
ATOM   4553  C CB    . LEU B 1 153 ? -5.931   -48.574  -32.464 1.00 26.62  ? 153  LEU B CB    1 
ATOM   4554  C CG    . LEU B 1 153 ? -7.390   -48.563  -32.953 1.00 25.35  ? 153  LEU B CG    1 
ATOM   4555  C CD1   . LEU B 1 153 ? -8.135   -49.786  -32.459 1.00 20.93  ? 153  LEU B CD1   1 
ATOM   4556  C CD2   . LEU B 1 153 ? -8.117   -47.293  -32.559 1.00 23.99  ? 153  LEU B CD2   1 
ATOM   4557  N N     . CYS B 1 154 ? -2.713   -48.226  -32.829 1.00 27.08  ? 154  CYS B N     1 
ATOM   4558  C CA    . CYS B 1 154 ? -1.372   -48.227  -32.307 1.00 27.91  ? 154  CYS B CA    1 
ATOM   4559  C C     . CYS B 1 154 ? -0.545   -47.017  -32.676 1.00 33.31  ? 154  CYS B C     1 
ATOM   4560  O O     . CYS B 1 154 ? 0.362    -46.683  -31.997 1.00 35.04  ? 154  CYS B O     1 
ATOM   4561  C CB    . CYS B 1 154 ? -0.637   -49.456  -32.770 1.00 23.37  ? 154  CYS B CB    1 
ATOM   4562  S SG    . CYS B 1 154 ? -1.016   -50.985  -31.971 1.00 28.77  ? 154  CYS B SG    1 
ATOM   4563  N N     . ARG B 1 155 ? -0.829   -46.382  -33.791 1.00 34.94  ? 155  ARG B N     1 
ATOM   4564  C CA    . ARG B 1 155 ? -0.001   -45.283  -34.232 1.00 32.37  ? 155  ARG B CA    1 
ATOM   4565  C C     . ARG B 1 155 ? -0.528   -43.885  -34.236 1.00 33.13  ? 155  ARG B C     1 
ATOM   4566  O O     . ARG B 1 155 ? 0.214    -42.989  -34.406 1.00 36.28  ? 155  ARG B O     1 
ATOM   4567  C CB    . ARG B 1 155 ? 0.508    -45.596  -35.618 1.00 31.50  ? 155  ARG B CB    1 
ATOM   4568  C CG    . ARG B 1 155 ? 1.256    -46.892  -35.687 1.00 42.05  ? 155  ARG B CG    1 
ATOM   4569  C CD    . ARG B 1 155 ? 1.612    -47.254  -37.094 1.00 48.61  ? 155  ARG B CD    1 
ATOM   4570  N NE    . ARG B 1 155 ? 2.277    -46.142  -37.721 1.00 65.55  ? 155  ARG B NE    1 
ATOM   4571  C CZ    . ARG B 1 155 ? 2.888    -46.187  -38.886 1.00 58.71  ? 155  ARG B CZ    1 
ATOM   4572  N NH1   . ARG B 1 155 ? 2.935    -47.302  -39.567 1.00 54.14  ? 155  ARG B NH1   1 
ATOM   4573  N NH2   . ARG B 1 155 ? 3.446    -45.106  -39.356 1.00 50.43  ? 155  ARG B NH2   1 
ATOM   4574  N N     . ASN B 1 156 ? -1.791   -43.680  -33.987 1.00 31.51  ? 156  ASN B N     1 
ATOM   4575  C CA    . ASN B 1 156 ? -2.311   -42.347  -34.094 1.00 32.85  ? 156  ASN B CA    1 
ATOM   4576  C C     . ASN B 1 156 ? -2.858   -41.661  -32.875 1.00 36.30  ? 156  ASN B C     1 
ATOM   4577  O O     . ASN B 1 156 ? -3.347   -40.571  -32.955 1.00 32.40  ? 156  ASN B O     1 
ATOM   4578  C CB    . ASN B 1 156 ? -3.384   -42.356  -35.172 1.00 35.68  ? 156  ASN B CB    1 
ATOM   4579  C CG    . ASN B 1 156 ? -2.820   -42.521  -36.547 1.00 36.25  ? 156  ASN B CG    1 
ATOM   4580  O OD1   . ASN B 1 156 ? -2.376   -41.593  -37.137 1.00 45.31  ? 156  ASN B OD1   1 
ATOM   4581  N ND2   . ASN B 1 156 ? -2.829   -43.692  -37.038 1.00 37.51  ? 156  ASN B ND2   1 
ATOM   4582  N N     . TYR B 1 157 ? -2.860   -42.353  -31.752 1.00 30.82  ? 157  TYR B N     1 
ATOM   4583  C CA    . TYR B 1 157 ? -3.425   -41.849  -30.529 1.00 33.86  ? 157  TYR B CA    1 
ATOM   4584  C C     . TYR B 1 157 ? -2.499   -41.735  -29.324 1.00 37.88  ? 157  TYR B C     1 
ATOM   4585  O O     . TYR B 1 157 ? -2.991   -41.624  -28.231 1.00 34.89  ? 157  TYR B O     1 
ATOM   4586  C CB    . TYR B 1 157 ? -4.686   -42.670  -30.197 1.00 34.69  ? 157  TYR B CB    1 
ATOM   4587  C CG    . TYR B 1 157 ? -5.633   -42.763  -31.360 1.00 32.49  ? 157  TYR B CG    1 
ATOM   4588  C CD1   . TYR B 1 157 ? -6.485   -41.743  -31.641 1.00 32.95  ? 157  TYR B CD1   1 
ATOM   4589  C CD2   . TYR B 1 157 ? -5.542   -43.783  -32.263 1.00 27.75  ? 157  TYR B CD2   1 
ATOM   4590  C CE1   . TYR B 1 157 ? -7.282   -41.775  -32.730 1.00 28.75  ? 157  TYR B CE1   1 
ATOM   4591  C CE2   . TYR B 1 157 ? -6.344   -43.819  -33.357 1.00 28.16  ? 157  TYR B CE2   1 
ATOM   4592  C CZ    . TYR B 1 157 ? -7.219   -42.801  -33.570 1.00 29.25  ? 157  TYR B CZ    1 
ATOM   4593  O OH    . TYR B 1 157 ? -8.030   -42.785  -34.634 1.00 29.92  ? 157  TYR B OH    1 
ATOM   4594  N N     . GLY B 1 158 ? -1.182   -41.762  -29.521 1.00 33.13  ? 158  GLY B N     1 
ATOM   4595  C CA    . GLY B 1 158 ? -0.254   -41.712  -28.405 1.00 31.91  ? 158  GLY B CA    1 
ATOM   4596  C C     . GLY B 1 158 ? -0.209   -43.051  -27.652 1.00 36.81  ? 158  GLY B C     1 
ATOM   4597  O O     . GLY B 1 158 ? -0.691   -44.058  -28.171 1.00 28.79  ? 158  GLY B O     1 
ATOM   4598  N N     . PRO B 1 159 ? 0.366    -43.094  -26.419 1.00 41.34  ? 159  PRO B N     1 
ATOM   4599  C CA    . PRO B 1 159 ? 0.416    -44.334  -25.635 1.00 40.03  ? 159  PRO B CA    1 
ATOM   4600  C C     . PRO B 1 159 ? -0.975   -44.850  -25.257 1.00 34.15  ? 159  PRO B C     1 
ATOM   4601  O O     . PRO B 1 159 ? -1.831   -44.092  -24.830 1.00 31.12  ? 159  PRO B O     1 
ATOM   4602  C CB    . PRO B 1 159 ? 1.271    -44.007  -24.398 1.00 38.72  ? 159  PRO B CB    1 
ATOM   4603  C CG    . PRO B 1 159 ? 1.728    -42.559  -24.588 1.00 41.79  ? 159  PRO B CG    1 
ATOM   4604  C CD    . PRO B 1 159 ? 0.956    -41.934  -25.719 1.00 41.19  ? 159  PRO B CD    1 
ATOM   4605  N N     . VAL B 1 160 ? -1.206   -46.140  -25.449 1.00 30.96  ? 160  VAL B N     1 
ATOM   4606  C CA    . VAL B 1 160 ? -2.511   -46.729  -25.241 1.00 33.87  ? 160  VAL B CA    1 
ATOM   4607  C C     . VAL B 1 160 ? -2.399   -47.644  -24.015 1.00 32.98  ? 160  VAL B C     1 
ATOM   4608  O O     . VAL B 1 160 ? -1.442   -48.407  -23.866 1.00 30.45  ? 160  VAL B O     1 
ATOM   4609  C CB    . VAL B 1 160 ? -2.751   -47.517  -26.548 1.00 35.21  ? 160  VAL B CB    1 
ATOM   4610  C CG1   . VAL B 1 160 ? -3.928   -48.485  -26.482 1.00 30.01  ? 160  VAL B CG1   1 
ATOM   4611  C CG2   . VAL B 1 160 ? -2.927   -46.596  -27.748 1.00 35.86  ? 160  VAL B CG2   1 
ATOM   4612  N N     . GLY B 1 161 ? -3.410   -47.601  -23.151 1.00 31.20  ? 161  GLY B N     1 
ATOM   4613  C CA    . GLY B 1 161 ? -3.390   -48.442  -21.972 1.00 27.55  ? 161  GLY B CA    1 
ATOM   4614  C C     . GLY B 1 161 ? -3.418   -49.922  -22.337 1.00 25.19  ? 161  GLY B C     1 
ATOM   4615  O O     . GLY B 1 161 ? -2.692   -50.729  -21.733 1.00 22.10  ? 161  GLY B O     1 
ATOM   4616  N N     . GLY B 1 162 ? -4.255   -50.284  -23.316 1.00 26.63  ? 162  GLY B N     1 
ATOM   4617  C CA    . GLY B 1 162 ? -4.390   -51.706  -23.626 1.00 25.60  ? 162  GLY B CA    1 
ATOM   4618  C C     . GLY B 1 162 ? -5.388   -51.943  -24.761 1.00 28.03  ? 162  GLY B C     1 
ATOM   4619  O O     . GLY B 1 162 ? -6.082   -51.019  -25.233 1.00 27.59  ? 162  GLY B O     1 
ATOM   4620  N N     . PHE B 1 163 ? -5.427   -53.217  -25.182 1.00 25.15  ? 163  PHE B N     1 
ATOM   4621  C CA    . PHE B 1 163 ? -6.329   -53.720  -26.200 1.00 22.83  ? 163  PHE B CA    1 
ATOM   4622  C C     . PHE B 1 163 ? -7.078   -54.874  -25.578 1.00 24.75  ? 163  PHE B C     1 
ATOM   4623  O O     . PHE B 1 163 ? -6.510   -55.644  -24.791 1.00 25.19  ? 163  PHE B O     1 
ATOM   4624  C CB    . PHE B 1 163 ? -5.534   -54.257  -27.395 1.00 22.38  ? 163  PHE B CB    1 
ATOM   4625  C CG    . PHE B 1 163 ? -4.919   -53.137  -28.225 1.00 22.24  ? 163  PHE B CG    1 
ATOM   4626  C CD1   . PHE B 1 163 ? -5.626   -52.567  -29.283 1.00 23.54  ? 163  PHE B CD1   1 
ATOM   4627  C CD2   . PHE B 1 163 ? -3.667   -52.607  -27.902 1.00 22.73  ? 163  PHE B CD2   1 
ATOM   4628  C CE1   . PHE B 1 163 ? -5.089   -51.500  -30.015 1.00 23.79  ? 163  PHE B CE1   1 
ATOM   4629  C CE2   . PHE B 1 163 ? -3.134   -51.530  -28.624 1.00 24.99  ? 163  PHE B CE2   1 
ATOM   4630  C CZ    . PHE B 1 163 ? -3.830   -50.993  -29.697 1.00 23.46  ? 163  PHE B CZ    1 
ATOM   4631  N N     . TRP B 1 164 ? -8.361   -54.962  -25.942 1.00 26.08  ? 164  TRP B N     1 
ATOM   4632  C CA    . TRP B 1 164 ? -9.258   -55.978  -25.421 1.00 22.94  ? 164  TRP B CA    1 
ATOM   4633  C C     . TRP B 1 164 ? -9.848   -56.686  -26.644 1.00 23.04  ? 164  TRP B C     1 
ATOM   4634  O O     . TRP B 1 164 ? -10.690  -56.136  -27.372 1.00 24.83  ? 164  TRP B O     1 
ATOM   4635  C CB    . TRP B 1 164 ? -10.320  -55.244  -24.578 1.00 22.38  ? 164  TRP B CB    1 
ATOM   4636  C CG    . TRP B 1 164 ? -10.969  -56.030  -23.456 1.00 22.92  ? 164  TRP B CG    1 
ATOM   4637  C CD1   . TRP B 1 164 ? -10.681  -55.934  -22.120 1.00 21.65  ? 164  TRP B CD1   1 
ATOM   4638  C CD2   . TRP B 1 164 ? -12.041  -56.994  -23.563 1.00 20.80  ? 164  TRP B CD2   1 
ATOM   4639  N NE1   . TRP B 1 164 ? -11.481  -56.778  -21.397 1.00 22.21  ? 164  TRP B NE1   1 
ATOM   4640  C CE2   . TRP B 1 164 ? -12.337  -57.431  -22.244 1.00 22.08  ? 164  TRP B CE2   1 
ATOM   4641  C CE3   . TRP B 1 164 ? -12.794  -57.513  -24.636 1.00 22.79  ? 164  TRP B CE3   1 
ATOM   4642  C CZ2   . TRP B 1 164 ? -13.339  -58.376  -21.968 1.00 20.60  ? 164  TRP B CZ2   1 
ATOM   4643  C CZ3   . TRP B 1 164 ? -13.794  -58.436  -24.368 1.00 22.68  ? 164  TRP B CZ3   1 
ATOM   4644  C CH2   . TRP B 1 164 ? -14.071  -58.848  -23.048 1.00 21.29  ? 164  TRP B CH2   1 
ATOM   4645  N N     . PHE B 1 165 ? -9.343   -57.885  -26.902 1.00 19.98  ? 165  PHE B N     1 
ATOM   4646  C CA    . PHE B 1 165 ? -9.653   -58.609  -28.131 1.00 21.87  ? 165  PHE B CA    1 
ATOM   4647  C C     . PHE B 1 165 ? -10.762  -59.609  -27.866 1.00 24.27  ? 165  PHE B C     1 
ATOM   4648  O O     . PHE B 1 165 ? -10.693  -60.404  -26.924 1.00 22.54  ? 165  PHE B O     1 
ATOM   4649  C CB    . PHE B 1 165 ? -8.459   -59.348  -28.748 1.00 20.73  ? 165  PHE B CB    1 
ATOM   4650  C CG    . PHE B 1 165 ? -7.513   -58.344  -29.402 1.00 24.31  ? 165  PHE B CG    1 
ATOM   4651  C CD1   . PHE B 1 165 ? -7.889   -57.667  -30.560 1.00 24.01  ? 165  PHE B CD1   1 
ATOM   4652  C CD2   . PHE B 1 165 ? -6.266   -58.060  -28.852 1.00 20.71  ? 165  PHE B CD2   1 
ATOM   4653  C CE1   . PHE B 1 165 ? -7.023   -56.760  -31.176 1.00 25.38  ? 165  PHE B CE1   1 
ATOM   4654  C CE2   . PHE B 1 165 ? -5.421   -57.137  -29.456 1.00 23.20  ? 165  PHE B CE2   1 
ATOM   4655  C CZ    . PHE B 1 165 ? -5.799   -56.462  -30.603 1.00 23.86  ? 165  PHE B CZ    1 
ATOM   4656  N N     . ASP B 1 166 ? -11.767  -59.589  -28.740 1.00 30.32  ? 166  ASP B N     1 
ATOM   4657  C CA    . ASP B 1 166 ? -12.882  -60.493  -28.565 1.00 30.71  ? 166  ASP B CA    1 
ATOM   4658  C C     . ASP B 1 166 ? -13.237  -61.183  -29.881 1.00 34.32  ? 166  ASP B C     1 
ATOM   4659  O O     . ASP B 1 166 ? -13.601  -60.512  -30.848 1.00 35.38  ? 166  ASP B O     1 
ATOM   4660  C CB    . ASP B 1 166 ? -14.042  -59.666  -28.054 1.00 29.01  ? 166  ASP B CB    1 
ATOM   4661  C CG    . ASP B 1 166 ? -15.362  -60.423  -27.994 1.00 36.44  ? 166  ASP B CG    1 
ATOM   4662  O OD1   . ASP B 1 166 ? -15.342  -61.607  -27.566 1.00 36.23  ? 166  ASP B OD1   1 
ATOM   4663  O OD2   . ASP B 1 166 ? -16.386  -59.829  -28.364 1.00 38.68  ? 166  ASP B OD2   1 
ATOM   4664  N N     . GLY B 1 167 ? -13.204  -62.524  -29.927 1.00 45.06  ? 167  GLY B N     1 
ATOM   4665  C CA    . GLY B 1 167 ? -13.947  -63.167  -31.010 1.00 55.56  ? 167  GLY B CA    1 
ATOM   4666  C C     . GLY B 1 167 ? -13.198  -64.269  -31.759 1.00 63.19  ? 167  GLY B C     1 
ATOM   4667  O O     . GLY B 1 167 ? -13.732  -64.826  -32.728 1.00 73.65  ? 167  GLY B O     1 
ATOM   4668  N N     . ASN B 1 168 ? -11.965  -64.578  -31.327 1.00 63.20  ? 168  ASN B N     1 
ATOM   4669  C CA    . ASN B 1 168 ? -11.210  -65.682  -31.916 1.00 62.31  ? 168  ASN B CA    1 
ATOM   4670  C C     . ASN B 1 168 ? -11.972  -66.991  -31.695 1.00 61.07  ? 168  ASN B C     1 
ATOM   4671  O O     . ASN B 1 168 ? -11.807  -67.919  -32.485 1.00 61.81  ? 168  ASN B O     1 
ATOM   4672  C CB    . ASN B 1 168 ? -9.770   -65.767  -31.405 1.00 52.12  ? 168  ASN B CB    1 
ATOM   4673  C CG    . ASN B 1 168 ? -8.877   -64.642  -31.883 1.00 52.51  ? 168  ASN B CG    1 
ATOM   4674  O OD1   . ASN B 1 168 ? -9.357   -63.582  -32.291 1.00 54.57  ? 168  ASN B OD1   1 
ATOM   4675  N ND2   . ASN B 1 168 ? -7.571   -64.857  -31.835 1.00 47.27  ? 168  ASN B ND2   1 
ATOM   4676  N N     . TRP B 1 169 ? -12.828  -67.025  -30.656 1.00 52.44  ? 169  TRP B N     1 
ATOM   4677  C CA    . TRP B 1 169 ? -13.697  -68.154  -30.332 1.00 57.00  ? 169  TRP B CA    1 
ATOM   4678  C C     . TRP B 1 169 ? -14.634  -68.514  -31.498 1.00 60.75  ? 169  TRP B C     1 
ATOM   4679  O O     . TRP B 1 169 ? -15.183  -69.618  -31.498 1.00 52.15  ? 169  TRP B O     1 
ATOM   4680  C CB    . TRP B 1 169 ? -14.499  -67.877  -29.042 1.00 59.59  ? 169  TRP B CB    1 
ATOM   4681  C CG    . TRP B 1 169 ? -15.077  -66.477  -28.978 1.00 61.82  ? 169  TRP B CG    1 
ATOM   4682  C CD1   . TRP B 1 169 ? -14.586  -65.420  -28.270 1.00 56.98  ? 169  TRP B CD1   1 
ATOM   4683  C CD2   . TRP B 1 169 ? -16.228  -65.974  -29.699 1.00 53.10  ? 169  TRP B CD2   1 
ATOM   4684  N NE1   . TRP B 1 169 ? -15.349  -64.304  -28.481 1.00 55.08  ? 169  TRP B NE1   1 
ATOM   4685  C CE2   . TRP B 1 169 ? -16.365  -64.612  -29.345 1.00 57.03  ? 169  TRP B CE2   1 
ATOM   4686  C CE3   . TRP B 1 169 ? -17.160  -66.547  -30.584 1.00 48.85  ? 169  TRP B CE3   1 
ATOM   4687  C CZ2   . TRP B 1 169 ? -17.397  -63.817  -29.844 1.00 52.79  ? 169  TRP B CZ2   1 
ATOM   4688  C CZ3   . TRP B 1 169 ? -18.171  -65.761  -31.095 1.00 53.14  ? 169  TRP B CZ3   1 
ATOM   4689  C CH2   . TRP B 1 169 ? -18.274  -64.411  -30.730 1.00 60.75  ? 169  TRP B CH2   1 
ATOM   4690  N N     . ASN B 1 170 ? -14.825  -67.596  -32.472 1.00 56.57  ? 170  ASN B N     1 
ATOM   4691  C CA    . ASN B 1 170 ? -15.689  -67.879  -33.601 1.00 52.37  ? 170  ASN B CA    1 
ATOM   4692  C C     . ASN B 1 170 ? -15.065  -68.935  -34.525 1.00 60.96  ? 170  ASN B C     1 
ATOM   4693  O O     . ASN B 1 170 ? -15.788  -69.704  -35.153 1.00 68.44  ? 170  ASN B O     1 
ATOM   4694  C CB    . ASN B 1 170 ? -16.099  -66.628  -34.363 1.00 48.76  ? 170  ASN B CB    1 
ATOM   4695  C CG    . ASN B 1 170 ? -16.892  -66.991  -35.605 1.00 49.59  ? 170  ASN B CG    1 
ATOM   4696  O OD1   . ASN B 1 170 ? -18.048  -67.390  -35.469 1.00 48.07  ? 170  ASN B OD1   1 
ATOM   4697  N ND2   . ASN B 1 170 ? -16.328  -66.884  -36.808 1.00 41.35  ? 170  ASN B ND2   1 
ATOM   4698  N N     . LYS B 1 171 ? -13.735  -68.946  -34.659 1.00 63.42  ? 171  LYS B N     1 
ATOM   4699  C CA    . LYS B 1 171 ? -13.033  -69.978  -35.421 1.00 64.58  ? 171  LYS B CA    1 
ATOM   4700  C C     . LYS B 1 171 ? -11.911  -70.556  -34.555 1.00 62.85  ? 171  LYS B C     1 
ATOM   4701  O O     . LYS B 1 171 ? -10.771  -70.100  -34.652 1.00 60.18  ? 171  LYS B O     1 
ATOM   4702  C CB    . LYS B 1 171 ? -12.431  -69.393  -36.709 1.00 58.10  ? 171  LYS B CB    1 
ATOM   4703  C CG    . LYS B 1 171 ? -13.415  -68.880  -37.757 1.00 57.71  ? 171  LYS B CG    1 
ATOM   4704  C CD    . LYS B 1 171 ? -12.750  -68.232  -38.978 1.00 63.94  ? 171  LYS B CD    1 
ATOM   4705  C CE    . LYS B 1 171 ? -13.499  -68.628  -40.211 1.00 72.44  ? 171  LYS B CE    1 
ATOM   4706  N NZ    . LYS B 1 171 ? -13.505  -67.597  -41.245 1.00 71.33  ? 171  LYS B NZ    1 
ATOM   4707  N N     . LYS B 1 172 ? -12.248  -71.525  -33.687 1.00 74.37  ? 172  LYS B N     1 
ATOM   4708  C CA    . LYS B 1 172 ? -11.330  -72.014  -32.657 1.00 81.45  ? 172  LYS B CA    1 
ATOM   4709  C C     . LYS B 1 172 ? -10.102  -72.676  -33.286 1.00 89.97  ? 172  LYS B C     1 
ATOM   4710  O O     . LYS B 1 172 ? -9.037   -72.721  -32.669 1.00 78.87  ? 172  LYS B O     1 
ATOM   4711  C CB    . LYS B 1 172 ? -11.947  -72.980  -31.634 1.00 82.04  ? 172  LYS B CB    1 
ATOM   4712  C CG    . LYS B 1 172 ? -13.187  -72.561  -30.873 1.00 98.22  ? 172  LYS B CG    1 
ATOM   4713  C CD    . LYS B 1 172 ? -13.605  -73.686  -29.920 1.00 107.06 ? 172  LYS B CD    1 
ATOM   4714  C CE    . LYS B 1 172 ? -14.977  -73.571  -29.300 1.00 109.82 ? 172  LYS B CE    1 
ATOM   4715  N NZ    . LYS B 1 172 ? -15.177  -72.243  -28.707 1.00 90.15  ? 172  LYS B NZ    1 
ATOM   4716  N N     . ASP B 1 173 ? -10.252  -73.190  -34.524 1.00 94.12  ? 173  ASP B N     1 
ATOM   4717  C CA    . ASP B 1 173 ? -9.247   -74.032  -35.161 1.00 87.55  ? 173  ASP B CA    1 
ATOM   4718  C C     . ASP B 1 173 ? -8.309   -73.237  -36.076 1.00 75.99  ? 173  ASP B C     1 
ATOM   4719  O O     . ASP B 1 173 ? -7.251   -73.742  -36.438 1.00 73.47  ? 173  ASP B O     1 
ATOM   4720  C CB    . ASP B 1 173 ? -9.874   -75.269  -35.788 1.00 100.58 ? 173  ASP B CB    1 
ATOM   4721  C CG    . ASP B 1 173 ? -10.463  -76.262  -34.792 1.00 108.48 ? 173  ASP B CG    1 
ATOM   4722  O OD1   . ASP B 1 173 ? -10.109  -76.203  -33.586 1.00 91.92  ? 173  ASP B OD1   1 
ATOM   4723  O OD2   . ASP B 1 173 ? -11.318  -77.055  -35.212 1.00 109.98 ? 173  ASP B OD2   1 
ATOM   4724  N N     . ALA B 1 174 ? -8.666   -71.999  -36.449 1.00 65.52  ? 174  ALA B N     1 
ATOM   4725  C CA    . ALA B 1 174 ? -7.927   -71.249  -37.455 1.00 55.60  ? 174  ALA B CA    1 
ATOM   4726  C C     . ALA B 1 174 ? -6.590   -70.746  -36.907 1.00 52.36  ? 174  ALA B C     1 
ATOM   4727  O O     . ALA B 1 174 ? -6.399   -70.638  -35.698 1.00 48.77  ? 174  ALA B O     1 
ATOM   4728  C CB    . ALA B 1 174 ? -8.780   -70.105  -37.969 1.00 55.81  ? 174  ALA B CB    1 
ATOM   4729  N N     . ASP B 1 175 ? -5.677   -70.428  -37.819 1.00 48.68  ? 175  ASP B N     1 
ATOM   4730  C CA    . ASP B 1 175 ? -4.440   -69.767  -37.458 1.00 47.01  ? 175  ASP B CA    1 
ATOM   4731  C C     . ASP B 1 175 ? -4.719   -68.271  -37.538 1.00 46.95  ? 175  ASP B C     1 
ATOM   4732  O O     . ASP B 1 175 ? -4.900   -67.734  -38.635 1.00 41.25  ? 175  ASP B O     1 
ATOM   4733  C CB    . ASP B 1 175 ? -3.264   -70.233  -38.310 1.00 43.05  ? 175  ASP B CB    1 
ATOM   4734  C CG    . ASP B 1 175 ? -1.905   -69.606  -38.017 1.00 52.45  ? 175  ASP B CG    1 
ATOM   4735  O OD1   . ASP B 1 175 ? -1.820   -68.698  -37.166 1.00 53.81  ? 175  ASP B OD1   1 
ATOM   4736  O OD2   . ASP B 1 175 ? -0.943   -69.895  -38.746 1.00 60.41  ? 175  ASP B OD2   1 
ATOM   4737  N N     . TRP B 1 176 ? -4.699   -67.599  -36.371 1.00 41.85  ? 176  TRP B N     1 
ATOM   4738  C CA    . TRP B 1 176 ? -5.028   -66.183  -36.295 1.00 36.77  ? 176  TRP B CA    1 
ATOM   4739  C C     . TRP B 1 176 ? -3.790   -65.302  -36.413 1.00 36.73  ? 176  TRP B C     1 
ATOM   4740  O O     . TRP B 1 176 ? -3.913   -64.074  -36.383 1.00 42.52  ? 176  TRP B O     1 
ATOM   4741  C CB    . TRP B 1 176 ? -5.820   -65.855  -35.024 1.00 36.22  ? 176  TRP B CB    1 
ATOM   4742  C CG    . TRP B 1 176 ? -7.261   -66.292  -35.052 1.00 36.81  ? 176  TRP B CG    1 
ATOM   4743  C CD1   . TRP B 1 176 ? -7.777   -67.498  -34.686 1.00 39.04  ? 176  TRP B CD1   1 
ATOM   4744  C CD2   . TRP B 1 176 ? -8.383   -65.475  -35.451 1.00 38.47  ? 176  TRP B CD2   1 
ATOM   4745  N NE1   . TRP B 1 176 ? -9.139   -67.498  -34.841 1.00 44.74  ? 176  TRP B NE1   1 
ATOM   4746  C CE2   . TRP B 1 176 ? -9.544   -66.266  -35.303 1.00 42.01  ? 176  TRP B CE2   1 
ATOM   4747  C CE3   . TRP B 1 176 ? -8.512   -64.147  -35.898 1.00 40.15  ? 176  TRP B CE3   1 
ATOM   4748  C CZ2   . TRP B 1 176 ? -10.820  -65.785  -35.603 1.00 41.01  ? 176  TRP B CZ2   1 
ATOM   4749  C CZ3   . TRP B 1 176 ? -9.771   -63.671  -36.185 1.00 41.71  ? 176  TRP B CZ3   1 
ATOM   4750  C CH2   . TRP B 1 176 ? -10.907  -64.486  -36.058 1.00 41.40  ? 176  TRP B CH2   1 
ATOM   4751  N N     . HIS B 1 177 ? -2.644   -65.913  -36.569 1.00 37.14  ? 177  HIS B N     1 
ATOM   4752  C CA    . HIS B 1 177 ? -1.426   -65.170  -36.716 1.00 42.10  ? 177  HIS B CA    1 
ATOM   4753  C C     . HIS B 1 177 ? -1.194   -64.175  -35.606 1.00 37.31  ? 177  HIS B C     1 
ATOM   4754  O O     . HIS B 1 177 ? -0.795   -63.077  -35.841 1.00 32.53  ? 177  HIS B O     1 
ATOM   4755  C CB    . HIS B 1 177 ? -1.360   -64.525  -38.081 1.00 48.44  ? 177  HIS B CB    1 
ATOM   4756  C CG    . HIS B 1 177 ? -0.957   -65.464  -39.165 1.00 68.79  ? 177  HIS B CG    1 
ATOM   4757  N ND1   . HIS B 1 177 ? -1.808   -66.409  -39.684 1.00 72.71  ? 177  HIS B ND1   1 
ATOM   4758  C CD2   . HIS B 1 177 ? 0.208    -65.605  -39.827 1.00 63.83  ? 177  HIS B CD2   1 
ATOM   4759  C CE1   . HIS B 1 177 ? -1.187   -67.088  -40.618 1.00 74.18  ? 177  HIS B CE1   1 
ATOM   4760  N NE2   . HIS B 1 177 ? 0.038    -66.621  -40.723 1.00 77.29  ? 177  HIS B NE2   1 
ATOM   4761  N N     . LEU B 1 178 ? -1.395   -64.635  -34.387 1.00 34.84  ? 178  LEU B N     1 
ATOM   4762  C CA    . LEU B 1 178 ? -1.264   -63.841  -33.191 1.00 35.81  ? 178  LEU B CA    1 
ATOM   4763  C C     . LEU B 1 178 ? 0.102    -63.264  -32.942 1.00 39.75  ? 178  LEU B C     1 
ATOM   4764  O O     . LEU B 1 178 ? 0.198    -62.147  -32.520 1.00 40.90  ? 178  LEU B O     1 
ATOM   4765  C CB    . LEU B 1 178 ? -1.780   -64.597  -31.987 1.00 32.03  ? 178  LEU B CB    1 
ATOM   4766  C CG    . LEU B 1 178 ? -3.251   -64.928  -32.096 1.00 33.42  ? 178  LEU B CG    1 
ATOM   4767  C CD1   . LEU B 1 178 ? -3.737   -65.729  -30.920 1.00 25.35  ? 178  LEU B CD1   1 
ATOM   4768  C CD2   . LEU B 1 178 ? -4.023   -63.652  -32.237 1.00 27.80  ? 178  LEU B CD2   1 
ATOM   4769  N N     . PRO B 1 179 ? 1.167    -64.005  -33.251 1.00 36.06  ? 179  PRO B N     1 
ATOM   4770  C CA    . PRO B 1 179 ? 2.500    -63.474  -33.056 1.00 31.89  ? 179  PRO B CA    1 
ATOM   4771  C C     . PRO B 1 179 ? 2.720    -62.229  -33.870 1.00 32.94  ? 179  PRO B C     1 
ATOM   4772  O O     . PRO B 1 179 ? 3.352    -61.329  -33.410 1.00 34.82  ? 179  PRO B O     1 
ATOM   4773  C CB    . PRO B 1 179 ? 3.367    -64.589  -33.575 1.00 31.08  ? 179  PRO B CB    1 
ATOM   4774  C CG    . PRO B 1 179 ? 2.597    -65.789  -33.278 1.00 28.52  ? 179  PRO B CG    1 
ATOM   4775  C CD    . PRO B 1 179 ? 1.209    -65.431  -33.562 1.00 30.54  ? 179  PRO B CD    1 
ATOM   4776  N N     . GLU B 1 180 ? 2.263    -62.197  -35.096 1.00 32.35  ? 180  GLU B N     1 
ATOM   4777  C CA    . GLU B 1 180 ? 2.372    -61.001  -35.869 1.00 34.68  ? 180  GLU B CA    1 
ATOM   4778  C C     . GLU B 1 180 ? 1.506    -59.869  -35.352 1.00 33.92  ? 180  GLU B C     1 
ATOM   4779  O O     . GLU B 1 180 ? 1.938    -58.764  -35.313 1.00 33.80  ? 180  GLU B O     1 
ATOM   4780  C CB    . GLU B 1 180 ? 2.080    -61.291  -37.314 1.00 41.87  ? 180  GLU B CB    1 
ATOM   4781  C CG    . GLU B 1 180 ? 3.193    -62.001  -38.020 1.00 63.59  ? 180  GLU B CG    1 
ATOM   4782  C CD    . GLU B 1 180 ? 3.301    -63.470  -37.690 1.00 83.45  ? 180  GLU B CD    1 
ATOM   4783  O OE1   . GLU B 1 180 ? 2.279    -64.149  -37.523 1.00 71.77  ? 180  GLU B OE1   1 
ATOM   4784  O OE2   . GLU B 1 180 ? 4.456    -63.943  -37.633 1.00 114.32 ? 180  GLU B OE2   1 
ATOM   4785  N N     . LEU B 1 181 ? 0.271    -60.149  -34.982 1.00 31.26  ? 181  LEU B N     1 
ATOM   4786  C CA    . LEU B 1 181 ? -0.584   -59.112  -34.457 1.00 29.83  ? 181  LEU B CA    1 
ATOM   4787  C C     . LEU B 1 181 ? -0.105   -58.551  -33.130 1.00 30.23  ? 181  LEU B C     1 
ATOM   4788  O O     . LEU B 1 181 ? 0.014    -57.372  -32.962 1.00 27.11  ? 181  LEU B O     1 
ATOM   4789  C CB    . LEU B 1 181 ? -2.016   -59.621  -34.339 1.00 26.43  ? 181  LEU B CB    1 
ATOM   4790  C CG    . LEU B 1 181 ? -3.030   -58.680  -33.724 1.00 24.61  ? 181  LEU B CG    1 
ATOM   4791  C CD1   . LEU B 1 181 ? -3.207   -57.463  -34.573 1.00 22.44  ? 181  LEU B CD1   1 
ATOM   4792  C CD2   . LEU B 1 181 ? -4.340   -59.346  -33.484 1.00 22.71  ? 181  LEU B CD2   1 
ATOM   4793  N N     . TYR B 1 182 ? 0.216    -59.436  -32.215 1.00 28.37  ? 182  TYR B N     1 
ATOM   4794  C CA    . TYR B 1 182 ? 0.717    -59.029  -30.930 1.00 27.45  ? 182  TYR B CA    1 
ATOM   4795  C C     . TYR B 1 182 ? 2.109    -58.405  -31.045 1.00 34.07  ? 182  TYR B C     1 
ATOM   4796  O O     . TYR B 1 182 ? 2.403    -57.467  -30.355 1.00 32.38  ? 182  TYR B O     1 
ATOM   4797  C CB    . TYR B 1 182 ? 0.544    -60.108  -29.886 1.00 25.64  ? 182  TYR B CB    1 
ATOM   4798  C CG    . TYR B 1 182 ? -0.885   -60.573  -29.677 1.00 28.51  ? 182  TYR B CG    1 
ATOM   4799  C CD1   . TYR B 1 182 ? -1.968   -59.785  -30.005 1.00 24.99  ? 182  TYR B CD1   1 
ATOM   4800  C CD2   . TYR B 1 182 ? -1.147   -61.793  -29.116 1.00 29.28  ? 182  TYR B CD2   1 
ATOM   4801  C CE1   . TYR B 1 182 ? -3.240   -60.214  -29.798 1.00 21.71  ? 182  TYR B CE1   1 
ATOM   4802  C CE2   . TYR B 1 182 ? -2.428   -62.217  -28.912 1.00 28.20  ? 182  TYR B CE2   1 
ATOM   4803  C CZ    . TYR B 1 182 ? -3.467   -61.415  -29.252 1.00 26.02  ? 182  TYR B CZ    1 
ATOM   4804  O OH    . TYR B 1 182 ? -4.709   -61.858  -29.045 1.00 23.92  ? 182  TYR B OH    1 
ATOM   4805  N N     . GLY B 1 183 ? 2.936    -58.928  -31.952 1.00 31.78  ? 183  GLY B N     1 
ATOM   4806  C CA    . GLY B 1 183 ? 4.270    -58.415  -32.208 1.00 26.79  ? 183  GLY B CA    1 
ATOM   4807  C C     . GLY B 1 183 ? 4.217    -56.974  -32.714 1.00 28.87  ? 183  GLY B C     1 
ATOM   4808  O O     . GLY B 1 183 ? 4.986    -56.118  -32.277 1.00 35.49  ? 183  GLY B O     1 
ATOM   4809  N N     . MET B 1 184 ? 3.280    -56.696  -33.627 1.00 28.73  ? 184  MET B N     1 
ATOM   4810  C CA    . MET B 1 184 ? 3.092    -55.340  -34.126 1.00 28.69  ? 184  MET B CA    1 
ATOM   4811  C C     . MET B 1 184 ? 2.692    -54.431  -32.952 1.00 28.83  ? 184  MET B C     1 
ATOM   4812  O O     . MET B 1 184 ? 3.197    -53.317  -32.821 1.00 31.06  ? 184  MET B O     1 
ATOM   4813  C CB    . MET B 1 184 ? 2.104    -55.378  -35.306 1.00 37.48  ? 184  MET B CB    1 
ATOM   4814  C CG    . MET B 1 184 ? 1.803    -54.085  -36.044 1.00 42.53  ? 184  MET B CG    1 
ATOM   4815  S SD    . MET B 1 184 ? 0.575    -53.096  -35.184 1.00 58.16  ? 184  MET B SD    1 
ATOM   4816  C CE    . MET B 1 184 ? -0.903   -54.116  -35.262 1.00 43.54  ? 184  MET B CE    1 
ATOM   4817  N N     . ILE B 1 185 ? 1.820    -54.911  -32.049 1.00 27.50  ? 185  ILE B N     1 
ATOM   4818  C CA    . ILE B 1 185 ? 1.419    -54.077  -30.922 1.00 26.23  ? 185  ILE B CA    1 
ATOM   4819  C C     . ILE B 1 185 ? 2.640    -53.783  -30.043 1.00 27.98  ? 185  ILE B C     1 
ATOM   4820  O O     . ILE B 1 185 ? 2.845    -52.635  -29.632 1.00 26.64  ? 185  ILE B O     1 
ATOM   4821  C CB    . ILE B 1 185 ? 0.250    -54.683  -30.110 1.00 28.30  ? 185  ILE B CB    1 
ATOM   4822  C CG1   . ILE B 1 185 ? -1.021   -54.827  -30.965 1.00 25.47  ? 185  ILE B CG1   1 
ATOM   4823  C CG2   . ILE B 1 185 ? -0.009   -53.904  -28.815 1.00 21.68  ? 185  ILE B CG2   1 
ATOM   4824  C CD1   . ILE B 1 185 ? -2.110   -55.661  -30.311 1.00 24.87  ? 185  ILE B CD1   1 
ATOM   4825  N N     . ARG B 1 186 ? 3.443    -54.814  -29.738 1.00 25.84  ? 186  ARG B N     1 
ATOM   4826  C CA    . ARG B 1 186 ? 4.637    -54.617  -28.921 1.00 30.53  ? 186  ARG B CA    1 
ATOM   4827  C C     . ARG B 1 186 ? 5.617    -53.644  -29.580 1.00 34.78  ? 186  ARG B C     1 
ATOM   4828  O O     . ARG B 1 186 ? 6.288    -52.877  -28.895 1.00 36.93  ? 186  ARG B O     1 
ATOM   4829  C CB    . ARG B 1 186 ? 5.362    -55.924  -28.611 1.00 29.52  ? 186  ARG B CB    1 
ATOM   4830  C CG    . ARG B 1 186 ? 4.568    -56.844  -27.686 1.00 27.58  ? 186  ARG B CG    1 
ATOM   4831  C CD    . ARG B 1 186 ? 4.726    -56.324  -26.266 1.00 28.78  ? 186  ARG B CD    1 
ATOM   4832  N NE    . ARG B 1 186 ? 3.724    -57.036  -25.466 1.00 32.30  ? 186  ARG B NE    1 
ATOM   4833  C CZ    . ARG B 1 186 ? 2.738    -56.534  -24.715 1.00 28.73  ? 186  ARG B CZ    1 
ATOM   4834  N NH1   . ARG B 1 186 ? 2.660    -55.237  -24.439 1.00 24.99  ? 186  ARG B NH1   1 
ATOM   4835  N NH2   . ARG B 1 186 ? 1.837    -57.385  -24.239 1.00 22.26  ? 186  ARG B NH2   1 
ATOM   4836  N N     . HIS B 1 187 ? 5.682    -53.643  -30.913 1.00 37.07  ? 187  HIS B N     1 
ATOM   4837  C CA    . HIS B 1 187 ? 6.533    -52.692  -31.610 1.00 36.06  ? 187  HIS B CA    1 
ATOM   4838  C C     . HIS B 1 187 ? 6.101    -51.250  -31.313 1.00 36.27  ? 187  HIS B C     1 
ATOM   4839  O O     . HIS B 1 187 ? 6.917    -50.451  -30.857 1.00 36.79  ? 187  HIS B O     1 
ATOM   4840  C CB    . HIS B 1 187 ? 6.819    -53.101  -33.070 1.00 40.30  ? 187  HIS B CB    1 
ATOM   4841  C CG    . HIS B 1 187 ? 7.699    -52.097  -33.768 1.00 54.50  ? 187  HIS B CG    1 
ATOM   4842  N ND1   . HIS B 1 187 ? 7.194    -51.222  -34.712 1.00 60.03  ? 187  HIS B ND1   1 
ATOM   4843  C CD2   . HIS B 1 187 ? 9.022    -51.774  -33.646 1.00 57.45  ? 187  HIS B CD2   1 
ATOM   4844  C CE1   . HIS B 1 187 ? 8.138    -50.369  -35.101 1.00 50.30  ? 187  HIS B CE1   1 
ATOM   4845  N NE2   . HIS B 1 187 ? 9.247    -50.690  -34.467 1.00 51.97  ? 187  HIS B NE2   1 
ATOM   4846  N N     . TYR B 1 188 ? 4.906    -50.864  -31.676 1.00 35.18  ? 188  TYR B N     1 
ATOM   4847  C CA    . TYR B 1 188 ? 4.390    -49.530  -31.418 1.00 33.49  ? 188  TYR B CA    1 
ATOM   4848  C C     . TYR B 1 188 ? 4.000    -49.116  -30.009 1.00 32.31  ? 188  TYR B C     1 
ATOM   4849  O O     . TYR B 1 188 ? 4.028    -47.978  -29.672 1.00 27.00  ? 188  TYR B O     1 
ATOM   4850  C CB    . TYR B 1 188 ? 3.253    -49.242  -32.364 1.00 37.37  ? 188  TYR B CB    1 
ATOM   4851  C CG    . TYR B 1 188 ? 3.635    -49.333  -33.791 1.00 40.65  ? 188  TYR B CG    1 
ATOM   4852  C CD1   . TYR B 1 188 ? 4.360    -48.350  -34.388 1.00 41.86  ? 188  TYR B CD1   1 
ATOM   4853  C CD2   . TYR B 1 188 ? 3.242    -50.385  -34.545 1.00 40.99  ? 188  TYR B CD2   1 
ATOM   4854  C CE1   . TYR B 1 188 ? 4.701    -48.425  -35.699 1.00 42.36  ? 188  TYR B CE1   1 
ATOM   4855  C CE2   . TYR B 1 188 ? 3.570    -50.465  -35.854 1.00 43.43  ? 188  TYR B CE2   1 
ATOM   4856  C CZ    . TYR B 1 188 ? 4.293    -49.476  -36.425 1.00 47.11  ? 188  TYR B CZ    1 
ATOM   4857  O OH    . TYR B 1 188 ? 4.619    -49.570  -37.729 1.00 47.87  ? 188  TYR B OH    1 
ATOM   4858  N N     . GLN B 1 189 ? 3.521    -50.082  -29.253 1.00 34.51  ? 189  GLN B N     1 
ATOM   4859  C CA    . GLN B 1 189 ? 3.027    -49.903  -27.913 1.00 30.73  ? 189  GLN B CA    1 
ATOM   4860  C C     . GLN B 1 189 ? 3.554    -50.961  -26.981 1.00 32.34  ? 189  GLN B C     1 
ATOM   4861  O O     . GLN B 1 189 ? 2.847    -51.824  -26.570 1.00 29.30  ? 189  GLN B O     1 
ATOM   4862  C CB    . GLN B 1 189 ? 1.512    -49.961  -27.936 1.00 25.58  ? 189  GLN B CB    1 
ATOM   4863  C CG    . GLN B 1 189 ? 0.824    -48.990  -28.847 1.00 23.79  ? 189  GLN B CG    1 
ATOM   4864  C CD    . GLN B 1 189 ? 0.724    -47.620  -28.259 1.00 26.68  ? 189  GLN B CD    1 
ATOM   4865  O OE1   . GLN B 1 189 ? 0.697    -47.466  -27.086 1.00 31.48  ? 189  GLN B OE1   1 
ATOM   4866  N NE2   . GLN B 1 189 ? 0.667    -46.641  -29.079 1.00 22.13  ? 189  GLN B NE2   1 
ATOM   4867  N N     . PRO B 1 190 ? 4.808    -50.857  -26.587 1.00 38.16  ? 190  PRO B N     1 
ATOM   4868  C CA    . PRO B 1 190 ? 5.414    -51.873  -25.736 1.00 33.72  ? 190  PRO B CA    1 
ATOM   4869  C C     . PRO B 1 190 ? 4.743    -52.057  -24.389 1.00 30.93  ? 190  PRO B C     1 
ATOM   4870  O O     . PRO B 1 190 ? 4.721    -53.125  -23.876 1.00 34.40  ? 190  PRO B O     1 
ATOM   4871  C CB    . PRO B 1 190 ? 6.852    -51.397  -25.620 1.00 31.66  ? 190  PRO B CB    1 
ATOM   4872  C CG    . PRO B 1 190 ? 6.810    -49.976  -25.888 1.00 30.48  ? 190  PRO B CG    1 
ATOM   4873  C CD    . PRO B 1 190 ? 5.762    -49.800  -26.916 1.00 34.39  ? 190  PRO B CD    1 
ATOM   4874  N N     . ASN B 1 191 ? 4.253    -50.994  -23.820 1.00 31.64  ? 191  ASN B N     1 
ATOM   4875  C CA    . ASN B 1 191 ? 3.589    -51.010  -22.570 1.00 35.65  ? 191  ASN B CA    1 
ATOM   4876  C C     . ASN B 1 191 ? 2.099    -51.312  -22.536 1.00 36.99  ? 191  ASN B C     1 
ATOM   4877  O O     . ASN B 1 191 ? 1.525    -51.301  -21.501 1.00 31.50  ? 191  ASN B O     1 
ATOM   4878  C CB    . ASN B 1 191 ? 3.831    -49.696  -21.911 1.00 40.92  ? 191  ASN B CB    1 
ATOM   4879  C CG    . ASN B 1 191 ? 4.704    -49.836  -20.748 1.00 58.85  ? 191  ASN B CG    1 
ATOM   4880  O OD1   . ASN B 1 191 ? 4.249    -50.207  -19.689 1.00 51.72  ? 191  ASN B OD1   1 
ATOM   4881  N ND2   . ASN B 1 191 ? 5.980    -49.571  -20.934 1.00 59.16  ? 191  ASN B ND2   1 
ATOM   4882  N N     . ALA B 1 192 ? 1.478    -51.530  -23.672 1.00 30.06  ? 192  ALA B N     1 
ATOM   4883  C CA    . ALA B 1 192 ? 0.079    -51.847  -23.702 1.00 27.24  ? 192  ALA B CA    1 
ATOM   4884  C C     . ALA B 1 192 ? -0.230   -53.183  -23.121 1.00 25.33  ? 192  ALA B C     1 
ATOM   4885  O O     . ALA B 1 192 ? 0.459    -54.114  -23.323 1.00 27.67  ? 192  ALA B O     1 
ATOM   4886  C CB    . ALA B 1 192 ? -0.461   -51.766  -25.108 1.00 23.91  ? 192  ALA B CB    1 
ATOM   4887  N N     . ILE B 1 193 ? -1.320   -53.247  -22.413 1.00 24.17  ? 193  ILE B N     1 
ATOM   4888  C CA    . ILE B 1 193 ? -1.781   -54.459  -21.836 1.00 24.66  ? 193  ILE B CA    1 
ATOM   4889  C C     . ILE B 1 193 ? -2.634   -55.146  -22.896 1.00 24.38  ? 193  ILE B C     1 
ATOM   4890  O O     . ILE B 1 193 ? -3.466   -54.547  -23.476 1.00 24.71  ? 193  ILE B O     1 
ATOM   4891  C CB    . ILE B 1 193 ? -2.609   -54.174  -20.582 1.00 26.44  ? 193  ILE B CB    1 
ATOM   4892  C CG1   . ILE B 1 193 ? -1.728   -53.827  -19.394 1.00 26.09  ? 193  ILE B CG1   1 
ATOM   4893  C CG2   . ILE B 1 193 ? -3.523   -55.321  -20.275 1.00 22.62  ? 193  ILE B CG2   1 
ATOM   4894  C CD1   . ILE B 1 193 ? -0.941   -54.965  -18.821 1.00 25.67  ? 193  ILE B CD1   1 
ATOM   4895  N N     . ILE B 1 194 ? -2.352   -56.392  -23.192 1.00 22.63  ? 194  ILE B N     1 
ATOM   4896  C CA    . ILE B 1 194 ? -3.136   -57.138  -24.159 1.00 21.09  ? 194  ILE B CA    1 
ATOM   4897  C C     . ILE B 1 194 ? -4.056   -58.106  -23.425 1.00 23.24  ? 194  ILE B C     1 
ATOM   4898  O O     . ILE B 1 194 ? -3.589   -59.060  -22.796 1.00 26.03  ? 194  ILE B O     1 
ATOM   4899  C CB    . ILE B 1 194 ? -2.253   -57.860  -25.190 1.00 19.34  ? 194  ILE B CB    1 
ATOM   4900  C CG1   . ILE B 1 194 ? -1.360   -56.878  -25.994 1.00 19.51  ? 194  ILE B CG1   1 
ATOM   4901  C CG2   . ILE B 1 194 ? -3.121   -58.722  -26.104 1.00 17.15  ? 194  ILE B CG2   1 
ATOM   4902  C CD1   . ILE B 1 194 ? -0.424   -57.577  -26.965 1.00 21.29  ? 194  ILE B CD1   1 
ATOM   4903  N N     . VAL B 1 195 ? -5.369   -57.882  -23.568 1.00 25.42  ? 195  VAL B N     1 
ATOM   4904  C CA    . VAL B 1 195 ? -6.384   -58.710  -22.938 1.00 24.78  ? 195  VAL B CA    1 
ATOM   4905  C C     . VAL B 1 195 ? -7.043   -59.548  -24.021 1.00 25.42  ? 195  VAL B C     1 
ATOM   4906  O O     . VAL B 1 195 ? -7.368   -59.037  -25.096 1.00 28.52  ? 195  VAL B O     1 
ATOM   4907  C CB    . VAL B 1 195 ? -7.463   -57.865  -22.231 1.00 25.19  ? 195  VAL B CB    1 
ATOM   4908  C CG1   . VAL B 1 195 ? -8.486   -58.755  -21.511 1.00 23.05  ? 195  VAL B CG1   1 
ATOM   4909  C CG2   . VAL B 1 195 ? -6.868   -56.814  -21.294 1.00 23.03  ? 195  VAL B CG2   1 
ATOM   4910  N N     . SER B 1 196 ? -7.333   -60.776  -23.675 1.00 27.62  ? 196  SER B N     1 
ATOM   4911  C CA    . SER B 1 196 ? -8.005   -61.679  -24.565 1.00 34.56  ? 196  SER B CA    1 
ATOM   4912  C C     . SER B 1 196 ? -9.190   -62.411  -23.945 1.00 33.03  ? 196  SER B C     1 
ATOM   4913  O O     . SER B 1 196 ? -9.108   -62.898  -22.876 1.00 25.87  ? 196  SER B O     1 
ATOM   4914  C CB    . SER B 1 196 ? -7.026   -62.669  -25.177 1.00 33.13  ? 196  SER B CB    1 
ATOM   4915  O OG    . SER B 1 196 ? -7.698   -63.518  -26.044 1.00 33.69  ? 196  SER B OG    1 
ATOM   4916  N N     . ASN B 1 197 ? -10.296  -62.404  -24.666 1.00 33.26  ? 197  ASN B N     1 
ATOM   4917  C CA    . ASN B 1 197 ? -11.544  -63.068  -24.346 1.00 39.92  ? 197  ASN B CA    1 
ATOM   4918  C C     . ASN B 1 197 ? -11.431  -64.568  -24.369 1.00 46.15  ? 197  ASN B C     1 
ATOM   4919  O O     . ASN B 1 197 ? -12.129  -65.253  -23.691 1.00 55.22  ? 197  ASN B O     1 
ATOM   4920  C CB    . ASN B 1 197 ? -12.662  -62.625  -25.240 1.00 47.09  ? 197  ASN B CB    1 
ATOM   4921  C CG    . ASN B 1 197 ? -13.924  -62.371  -24.473 1.00 51.82  ? 197  ASN B CG    1 
ATOM   4922  O OD1   . ASN B 1 197 ? -13.949  -62.465  -23.269 1.00 53.06  ? 197  ASN B OD1   1 
ATOM   4923  N ND2   . ASN B 1 197 ? -14.972  -62.060  -25.166 1.00 48.71  ? 197  ASN B ND2   1 
ATOM   4924  N N     . THR B 1 198 ? -10.633  -65.097  -25.257 1.00 65.91  ? 198  THR B N     1 
ATOM   4925  C CA    . THR B 1 198 ? -10.388  -66.517  -25.215 1.00 82.92  ? 198  THR B CA    1 
ATOM   4926  C C     . THR B 1 198 ? -8.904   -66.733  -25.319 1.00 90.06  ? 198  THR B C     1 
ATOM   4927  O O     . THR B 1 198 ? -8.433   -67.378  -26.241 1.00 94.39  ? 198  THR B O     1 
ATOM   4928  C CB    . THR B 1 198 ? -11.082  -67.254  -26.347 1.00 91.35  ? 198  THR B CB    1 
ATOM   4929  O OG1   . THR B 1 198 ? -10.956  -66.483  -27.543 1.00 86.74  ? 198  THR B OG1   1 
ATOM   4930  C CG2   . THR B 1 198 ? -12.538  -67.457  -26.000 1.00 64.68  ? 198  THR B CG2   1 
ATOM   4931  N N     . GLY B 1 199 ? -8.172   -66.228  -24.339 1.00 93.34  ? 199  GLY B N     1 
ATOM   4932  C CA    . GLY B 1 199 ? -6.728   -66.332  -24.325 1.00 92.66  ? 199  GLY B CA    1 
ATOM   4933  C C     . GLY B 1 199 ? -6.183   -67.544  -23.613 1.00 96.77  ? 199  GLY B C     1 
ATOM   4934  O O     . GLY B 1 199 ? -4.999   -67.780  -23.604 1.00 101.26 ? 199  GLY B O     1 
ATOM   4935  N N     . LEU B 1 200 ? -7.059   -68.312  -23.008 1.00 100.54 ? 200  LEU B N     1 
ATOM   4936  C CA    . LEU B 1 200 ? -6.658   -69.503  -22.313 1.00 100.04 ? 200  LEU B CA    1 
ATOM   4937  C C     . LEU B 1 200 ? -6.956   -70.679  -23.209 1.00 101.62 ? 200  LEU B C     1 
ATOM   4938  O O     . LEU B 1 200 ? -7.053   -70.538  -24.420 1.00 84.51  ? 200  LEU B O     1 
ATOM   4939  C CB    . LEU B 1 200 ? -7.444   -69.624  -21.022 1.00 95.14  ? 200  LEU B CB    1 
ATOM   4940  C CG    . LEU B 1 200 ? -6.768   -70.189  -19.792 1.00 101.67 ? 200  LEU B CG    1 
ATOM   4941  C CD1   . LEU B 1 200 ? -5.676   -69.255  -19.317 1.00 87.78  ? 200  LEU B CD1   1 
ATOM   4942  C CD2   . LEU B 1 200 ? -7.802   -70.358  -18.703 1.00 94.01  ? 200  LEU B CD2   1 
ATOM   4943  N N     . GLY B 1 204 ? -5.530   -74.385  -19.214 1.00 83.27  ? 204  GLY B N     1 
ATOM   4944  C CA    . GLY B 1 204 ? -4.406   -75.137  -19.810 1.00 97.70  ? 204  GLY B CA    1 
ATOM   4945  C C     . GLY B 1 204 ? -3.285   -74.218  -20.300 1.00 108.68 ? 204  GLY B C     1 
ATOM   4946  O O     . GLY B 1 204 ? -2.468   -73.743  -19.514 1.00 113.26 ? 204  GLY B O     1 
ATOM   4947  N N     . GLN B 1 205 ? -3.226   -74.013  -21.619 1.00 116.64 ? 205  GLN B N     1 
ATOM   4948  C CA    . GLN B 1 205 ? -2.238   -73.164  -22.273 1.00 105.19 ? 205  GLN B CA    1 
ATOM   4949  C C     . GLN B 1 205 ? -2.874   -71.830  -22.665 1.00 87.95  ? 205  GLN B C     1 
ATOM   4950  O O     . GLN B 1 205 ? -3.997   -71.802  -23.153 1.00 83.65  ? 205  GLN B O     1 
ATOM   4951  C CB    . GLN B 1 205 ? -1.685   -73.876  -23.511 1.00 109.68 ? 205  GLN B CB    1 
ATOM   4952  C CG    . GLN B 1 205 ? -0.335   -74.551  -23.286 1.00 115.05 ? 205  GLN B CG    1 
ATOM   4953  C CD    . GLN B 1 205 ? -0.212   -75.893  -23.978 1.00 125.82 ? 205  GLN B CD    1 
ATOM   4954  O OE1   . GLN B 1 205 ? -1.138   -76.357  -24.654 1.00 121.18 ? 205  GLN B OE1   1 
ATOM   4955  N NE2   . GLN B 1 205 ? 0.926    -76.548  -23.792 1.00 116.85 ? 205  GLN B NE2   1 
ATOM   4956  N N     . VAL B 1 206 ? -2.104   -70.736  -22.541 1.00 81.46  ? 206  VAL B N     1 
ATOM   4957  C CA    . VAL B 1 206 ? -2.457   -69.409  -23.047 1.00 71.16  ? 206  VAL B CA    1 
ATOM   4958  C C     . VAL B 1 206 ? -2.248   -69.327  -24.563 1.00 52.93  ? 206  VAL B C     1 
ATOM   4959  O O     . VAL B 1 206 ? -1.382   -70.004  -25.101 1.00 57.62  ? 206  VAL B O     1 
ATOM   4960  C CB    . VAL B 1 206 ? -1.693   -68.304  -22.288 1.00 62.60  ? 206  VAL B CB    1 
ATOM   4961  C CG1   . VAL B 1 206 ? -0.191   -68.326  -22.563 1.00 62.27  ? 206  VAL B CG1   1 
ATOM   4962  C CG2   . VAL B 1 206 ? -2.285   -66.929  -22.552 1.00 67.51  ? 206  VAL B CG2   1 
ATOM   4963  N N     . SER B 1 207 ? -3.021   -68.485  -25.251 1.00 44.77  ? 207  SER B N     1 
ATOM   4964  C CA    . SER B 1 207 ? -3.096   -68.628  -26.704 1.00 46.78  ? 207  SER B CA    1 
ATOM   4965  C C     . SER B 1 207 ? -1.920   -67.959  -27.437 1.00 44.53  ? 207  SER B C     1 
ATOM   4966  O O     . SER B 1 207 ? -1.713   -68.185  -28.627 1.00 37.55  ? 207  SER B O     1 
ATOM   4967  C CB    . SER B 1 207 ? -4.446   -68.217  -27.261 1.00 41.49  ? 207  SER B CB    1 
ATOM   4968  O OG    . SER B 1 207 ? -4.550   -66.805  -27.227 1.00 51.80  ? 207  SER B OG    1 
ATOM   4969  N N     . ASP B 1 208 ? -1.145   -67.132  -26.720 1.00 37.37  ? 208  ASP B N     1 
ATOM   4970  C CA    . ASP B 1 208 ? 0.039    -66.502  -27.263 1.00 31.19  ? 208  ASP B CA    1 
ATOM   4971  C C     . ASP B 1 208 ? 0.859    -65.908  -26.121 1.00 37.32  ? 208  ASP B C     1 
ATOM   4972  O O     . ASP B 1 208 ? 0.305    -65.301  -25.212 1.00 42.82  ? 208  ASP B O     1 
ATOM   4973  C CB    . ASP B 1 208 ? -0.287   -65.385  -28.230 1.00 29.91  ? 208  ASP B CB    1 
ATOM   4974  C CG    . ASP B 1 208 ? 0.930    -64.888  -29.014 1.00 37.86  ? 208  ASP B CG    1 
ATOM   4975  O OD1   . ASP B 1 208 ? 1.251    -65.500  -30.079 1.00 38.78  ? 208  ASP B OD1   1 
ATOM   4976  O OD2   . ASP B 1 208 ? 1.608    -63.958  -28.523 1.00 34.70  ? 208  ASP B OD2   1 
ATOM   4977  N N     . PRO B 1 209 ? 2.206    -66.030  -26.150 1.00 39.47  ? 209  PRO B N     1 
ATOM   4978  C CA    . PRO B 1 209 ? 3.062    -65.474  -25.096 1.00 36.52  ? 209  PRO B CA    1 
ATOM   4979  C C     . PRO B 1 209 ? 2.839    -63.990  -24.818 1.00 31.28  ? 209  PRO B C     1 
ATOM   4980  O O     . PRO B 1 209 ? 3.108    -63.527  -23.710 1.00 34.51  ? 209  PRO B O     1 
ATOM   4981  C CB    . PRO B 1 209 ? 4.509    -65.772  -25.574 1.00 33.87  ? 209  PRO B CB    1 
ATOM   4982  C CG    . PRO B 1 209 ? 4.269    -67.039  -26.414 1.00 33.03  ? 209  PRO B CG    1 
ATOM   4983  C CD    . PRO B 1 209 ? 2.982    -66.754  -27.177 1.00 33.31  ? 209  PRO B CD    1 
ATOM   4984  N N     . GLU B 1 210 ? 2.348    -63.236  -25.810 1.00 25.99  ? 210  GLU B N     1 
ATOM   4985  C CA    . GLU B 1 210 ? 2.227    -61.794  -25.636 1.00 27.75  ? 210  GLU B CA    1 
ATOM   4986  C C     . GLU B 1 210 ? 0.972    -61.380  -24.849 1.00 27.98  ? 210  GLU B C     1 
ATOM   4987  O O     . GLU B 1 210 ? 0.864    -60.223  -24.446 1.00 26.35  ? 210  GLU B O     1 
ATOM   4988  C CB    . GLU B 1 210 ? 2.325    -61.042  -26.963 1.00 27.58  ? 210  GLU B CB    1 
ATOM   4989  C CG    . GLU B 1 210 ? 3.753    -60.990  -27.495 1.00 38.11  ? 210  GLU B CG    1 
ATOM   4990  C CD    . GLU B 1 210 ? 4.793    -60.367  -26.561 1.00 41.02  ? 210  GLU B CD    1 
ATOM   4991  O OE1   . GLU B 1 210 ? 4.467    -59.603  -25.611 1.00 33.70  ? 210  GLU B OE1   1 
ATOM   4992  O OE2   . GLU B 1 210 ? 5.961    -60.755  -26.777 1.00 41.77  ? 210  GLU B OE2   1 
ATOM   4993  N N     . ILE B 1 211 ? 0.010    -62.296  -24.662 1.00 26.28  ? 211  ILE B N     1 
ATOM   4994  C CA    . ILE B 1 211 ? -1.181   -62.006  -23.873 1.00 25.97  ? 211  ILE B CA    1 
ATOM   4995  C C     . ILE B 1 211 ? -0.800   -61.716  -22.423 1.00 24.12  ? 211  ILE B C     1 
ATOM   4996  O O     . ILE B 1 211 ? 0.005    -62.431  -21.833 1.00 22.70  ? 211  ILE B O     1 
ATOM   4997  C CB    . ILE B 1 211 ? -2.190   -63.163  -23.983 1.00 27.41  ? 211  ILE B CB    1 
ATOM   4998  C CG1   . ILE B 1 211 ? -2.941   -63.057  -25.320 1.00 26.47  ? 211  ILE B CG1   1 
ATOM   4999  C CG2   . ILE B 1 211 ? -3.162   -63.164  -22.793 1.00 25.26  ? 211  ILE B CG2   1 
ATOM   5000  C CD1   . ILE B 1 211 ? -3.502   -64.383  -25.766 1.00 29.96  ? 211  ILE B CD1   1 
ATOM   5001  N N     . ASP B 1 212 ? -1.395   -60.659  -21.850 1.00 24.25  ? 212  ASP B N     1 
ATOM   5002  C CA    . ASP B 1 212 ? -1.116   -60.212  -20.489 1.00 23.86  ? 212  ASP B CA    1 
ATOM   5003  C C     . ASP B 1 212 ? -2.258   -60.569  -19.527 1.00 24.40  ? 212  ASP B C     1 
ATOM   5004  O O     . ASP B 1 212 ? -2.038   -60.734  -18.328 1.00 25.38  ? 212  ASP B O     1 
ATOM   5005  C CB    . ASP B 1 212 ? -0.882   -58.717  -20.477 1.00 23.27  ? 212  ASP B CB    1 
ATOM   5006  C CG    . ASP B 1 212 ? 0.312    -58.243  -21.298 1.00 26.70  ? 212  ASP B CG    1 
ATOM   5007  O OD1   . ASP B 1 212 ? 1.344    -58.960  -21.303 1.00 29.62  ? 212  ASP B OD1   1 
ATOM   5008  O OD2   . ASP B 1 212 ? 0.228    -57.130  -21.882 1.00 30.54  ? 212  ASP B OD2   1 
ATOM   5009  N N     . VAL B 1 213 ? -3.474   -60.548  -20.031 1.00 21.71  ? 213  VAL B N     1 
ATOM   5010  C CA    . VAL B 1 213 ? -4.677   -60.805  -19.280 1.00 22.22  ? 213  VAL B CA    1 
ATOM   5011  C C     . VAL B 1 213 ? -5.642   -61.726  -20.017 1.00 26.97  ? 213  VAL B C     1 
ATOM   5012  O O     . VAL B 1 213 ? -5.860   -61.592  -21.168 1.00 28.90  ? 213  VAL B O     1 
ATOM   5013  C CB    . VAL B 1 213 ? -5.425   -59.490  -18.941 1.00 20.05  ? 213  VAL B CB    1 
ATOM   5014  C CG1   . VAL B 1 213 ? -6.537   -59.695  -17.937 1.00 18.29  ? 213  VAL B CG1   1 
ATOM   5015  C CG2   . VAL B 1 213 ? -4.496   -58.414  -18.464 1.00 16.05  ? 213  VAL B CG2   1 
ATOM   5016  N N     . VAL B 1 214 ? -6.255   -62.617  -19.279 1.00 27.07  ? 214  VAL B N     1 
ATOM   5017  C CA    . VAL B 1 214 ? -7.227   -63.558  -19.728 1.00 30.48  ? 214  VAL B CA    1 
ATOM   5018  C C     . VAL B 1 214 ? -8.529   -63.268  -18.963 1.00 29.02  ? 214  VAL B C     1 
ATOM   5019  O O     . VAL B 1 214 ? -8.486   -62.806  -17.874 1.00 30.19  ? 214  VAL B O     1 
ATOM   5020  C CB    . VAL B 1 214 ? -6.660   -64.956  -19.488 1.00 32.75  ? 214  VAL B CB    1 
ATOM   5021  C CG1   . VAL B 1 214 ? -7.697   -65.987  -19.267 1.00 41.63  ? 214  VAL B CG1   1 
ATOM   5022  C CG2   . VAL B 1 214 ? -5.775   -65.346  -20.626 1.00 37.08  ? 214  VAL B CG2   1 
ATOM   5023  N N     . THR B 1 215 ? -9.677   -63.450  -19.585 1.00 29.51  ? 215  THR B N     1 
ATOM   5024  C CA    . THR B 1 215 ? -10.989  -63.250  -18.950 1.00 32.80  ? 215  THR B CA    1 
ATOM   5025  C C     . THR B 1 215 ? -11.638  -64.483  -18.322 1.00 37.64  ? 215  THR B C     1 
ATOM   5026  O O     . THR B 1 215 ? -11.428  -65.578  -18.744 1.00 44.44  ? 215  THR B O     1 
ATOM   5027  C CB    . THR B 1 215 ? -12.007  -62.657  -19.894 1.00 29.18  ? 215  THR B CB    1 
ATOM   5028  O OG1   . THR B 1 215 ? -12.235  -63.568  -20.942 1.00 26.62  ? 215  THR B OG1   1 
ATOM   5029  C CG2   . THR B 1 215 ? -11.548  -61.358  -20.426 1.00 24.59  ? 215  THR B CG2   1 
ATOM   5030  N N     . TYR B 1 216 ? -12.416  -64.279  -17.279 1.00 39.57  ? 216  TYR B N     1 
ATOM   5031  C CA    . TYR B 1 216 ? -13.059  -65.345  -16.554 1.00 38.95  ? 216  TYR B CA    1 
ATOM   5032  C C     . TYR B 1 216 ? -14.487  -64.996  -16.250 1.00 48.08  ? 216  TYR B C     1 
ATOM   5033  O O     . TYR B 1 216 ? -14.841  -63.852  -16.304 1.00 51.67  ? 216  TYR B O     1 
ATOM   5034  C CB    . TYR B 1 216 ? -12.341  -65.578  -15.230 1.00 44.72  ? 216  TYR B CB    1 
ATOM   5035  C CG    . TYR B 1 216 ? -10.927  -66.048  -15.347 1.00 49.00  ? 216  TYR B CG    1 
ATOM   5036  C CD1   . TYR B 1 216 ? -9.893   -65.164  -15.501 1.00 42.51  ? 216  TYR B CD1   1 
ATOM   5037  C CD2   . TYR B 1 216 ? -10.632  -67.378  -15.290 1.00 50.70  ? 216  TYR B CD2   1 
ATOM   5038  C CE1   . TYR B 1 216 ? -8.610   -65.596  -15.628 1.00 45.74  ? 216  TYR B CE1   1 
ATOM   5039  C CE2   . TYR B 1 216 ? -9.350   -67.823  -15.404 1.00 54.74  ? 216  TYR B CE2   1 
ATOM   5040  C CZ    . TYR B 1 216 ? -8.348   -66.929  -15.574 1.00 57.29  ? 216  TYR B CZ    1 
ATOM   5041  O OH    . TYR B 1 216 ? -7.089   -67.386  -15.670 1.00 58.74  ? 216  TYR B OH    1 
ATOM   5042  N N     . GLU B 1 217 ? -15.315  -65.997  -15.970 1.00 56.93  ? 217  GLU B N     1 
ATOM   5043  C CA    . GLU B 1 217 ? -16.708  -65.793  -15.605 1.00 54.12  ? 217  GLU B CA    1 
ATOM   5044  C C     . GLU B 1 217 ? -16.752  -65.163  -14.253 1.00 53.04  ? 217  GLU B C     1 
ATOM   5045  O O     . GLU B 1 217 ? -15.943  -65.474  -13.418 1.00 53.44  ? 217  GLU B O     1 
ATOM   5046  C CB    . GLU B 1 217 ? -17.484  -67.092  -15.539 1.00 62.36  ? 217  GLU B CB    1 
ATOM   5047  C CG    . GLU B 1 217 ? -17.036  -68.149  -16.496 1.00 89.18  ? 217  GLU B CG    1 
ATOM   5048  C CD    . GLU B 1 217 ? -18.186  -68.769  -17.242 1.00 109.73 ? 217  GLU B CD    1 
ATOM   5049  O OE1   . GLU B 1 217 ? -19.166  -68.050  -17.492 1.00 120.38 ? 217  GLU B OE1   1 
ATOM   5050  O OE2   . GLU B 1 217 ? -18.104  -69.955  -17.607 1.00 109.26 ? 217  GLU B OE2   1 
ATOM   5051  N N     . ARG B 1 218 ? -17.747  -64.338  -13.996 1.00 44.76  ? 218  ARG B N     1 
ATOM   5052  C CA    . ARG B 1 218 ? -17.829  -63.648  -12.715 1.00 57.76  ? 218  ARG B CA    1 
ATOM   5053  C C     . ARG B 1 218 ? -18.042  -64.506  -11.491 1.00 54.87  ? 218  ARG B C     1 
ATOM   5054  O O     . ARG B 1 218 ? -17.696  -64.124  -10.412 1.00 50.85  ? 218  ARG B O     1 
ATOM   5055  C CB    . ARG B 1 218 ? -18.782  -62.463  -12.740 1.00 51.01  ? 218  ARG B CB    1 
ATOM   5056  C CG    . ARG B 1 218 ? -20.186  -62.824  -13.043 1.00 54.64  ? 218  ARG B CG    1 
ATOM   5057  C CD    . ARG B 1 218 ? -20.998  -61.615  -13.407 1.00 64.13  ? 218  ARG B CD    1 
ATOM   5058  N NE    . ARG B 1 218 ? -22.335  -62.072  -13.666 1.00 55.52  ? 218  ARG B NE    1 
ATOM   5059  C CZ    . ARG B 1 218 ? -23.272  -62.094  -12.764 1.00 56.10  ? 218  ARG B CZ    1 
ATOM   5060  N NH1   . ARG B 1 218 ? -23.026  -61.630  -11.555 1.00 46.35  ? 218  ARG B NH1   1 
ATOM   5061  N NH2   . ARG B 1 218 ? -24.444  -62.576  -13.089 1.00 56.86  ? 218  ARG B NH2   1 
ATOM   5062  N N     . ARG B 1 219 ? -18.629  -65.664  -11.682 1.00 59.69  ? 219  ARG B N     1 
ATOM   5063  C CA    . ARG B 1 219 ? -18.893  -66.572  -10.613 1.00 62.02  ? 219  ARG B CA    1 
ATOM   5064  C C     . ARG B 1 219 ? -17.777  -67.552  -10.318 1.00 56.04  ? 219  ARG B C     1 
ATOM   5065  O O     . ARG B 1 219 ? -18.039  -68.478  -9.597  1.00 54.96  ? 219  ARG B O     1 
ATOM   5066  C CB    . ARG B 1 219 ? -20.160  -67.355  -10.888 1.00 63.54  ? 219  ARG B CB    1 
ATOM   5067  C CG    . ARG B 1 219 ? -21.436  -66.556  -10.839 1.00 68.80  ? 219  ARG B CG    1 
ATOM   5068  C CD    . ARG B 1 219 ? -22.480  -67.319  -11.606 1.00 76.85  ? 219  ARG B CD    1 
ATOM   5069  N NE    . ARG B 1 219 ? -23.814  -66.794  -11.452 1.00 91.85  ? 219  ARG B NE    1 
ATOM   5070  C CZ    . ARG B 1 219 ? -24.581  -66.410  -12.460 1.00 99.00  ? 219  ARG B CZ    1 
ATOM   5071  N NH1   . ARG B 1 219 ? -24.131  -66.479  -13.700 1.00 87.18  ? 219  ARG B NH1   1 
ATOM   5072  N NH2   . ARG B 1 219 ? -25.794  -65.945  -12.221 1.00 93.67  ? 219  ARG B NH2   1 
ATOM   5073  N N     . THR B 1 220 ? -16.584  -67.386  -10.895 1.00 47.97  ? 220  THR B N     1 
ATOM   5074  C CA    . THR B 1 220 ? -15.470  -68.303  -10.653 1.00 47.67  ? 220  THR B CA    1 
ATOM   5075  C C     . THR B 1 220 ? -15.268  -68.319  -9.153  1.00 56.43  ? 220  THR B C     1 
ATOM   5076  O O     . THR B 1 220 ? -15.052  -67.298  -8.563  1.00 48.24  ? 220  THR B O     1 
ATOM   5077  C CB    . THR B 1 220 ? -14.179  -67.771  -11.277 1.00 43.06  ? 220  THR B CB    1 
ATOM   5078  O OG1   . THR B 1 220 ? -14.332  -67.626  -12.675 1.00 46.73  ? 220  THR B OG1   1 
ATOM   5079  C CG2   . THR B 1 220 ? -13.087  -68.670  -11.029 1.00 39.97  ? 220  THR B CG2   1 
ATOM   5080  N N     . PRO B 1 221 ? -15.263  -69.508  -8.555  1.00 63.19  ? 221  PRO B N     1 
ATOM   5081  C CA    . PRO B 1 221 ? -15.268  -69.557  -7.088  1.00 59.19  ? 221  PRO B CA    1 
ATOM   5082  C C     . PRO B 1 221 ? -13.913  -69.271  -6.428  1.00 65.12  ? 221  PRO B C     1 
ATOM   5083  O O     . PRO B 1 221 ? -13.856  -68.662  -5.357  1.00 56.05  ? 221  PRO B O     1 
ATOM   5084  C CB    . PRO B 1 221 ? -15.903  -70.915  -6.754  1.00 57.70  ? 221  PRO B CB    1 
ATOM   5085  C CG    . PRO B 1 221 ? -15.652  -71.756  -8.018  1.00 57.60  ? 221  PRO B CG    1 
ATOM   5086  C CD    . PRO B 1 221 ? -15.339  -70.846  -9.182  1.00 60.10  ? 221  PRO B CD    1 
ATOM   5087  N N     . ASP B 1 222 ? -12.813  -69.690  -7.080  1.00 68.19  ? 222  ASP B N     1 
ATOM   5088  C CA    . ASP B 1 222 ? -11.500  -69.691  -6.434  1.00 68.00  ? 222  ASP B CA    1 
ATOM   5089  C C     . ASP B 1 222 ? -10.556  -68.755  -7.175  1.00 60.51  ? 222  ASP B C     1 
ATOM   5090  O O     . ASP B 1 222 ? -10.822  -68.407  -8.334  1.00 57.67  ? 222  ASP B O     1 
ATOM   5091  C CB    . ASP B 1 222 ? -10.837  -71.064  -6.446  1.00 80.13  ? 222  ASP B CB    1 
ATOM   5092  C CG    . ASP B 1 222 ? -11.681  -72.210  -5.900  1.00 89.23  ? 222  ASP B CG    1 
ATOM   5093  O OD1   . ASP B 1 222 ? -12.035  -72.164  -4.697  1.00 84.12  ? 222  ASP B OD1   1 
ATOM   5094  O OD2   . ASP B 1 222 ? -12.008  -73.129  -6.691  1.00 85.69  ? 222  ASP B OD2   1 
ATOM   5095  N N     . GLU B 1 223 ? -9.439   -68.420  -6.506  1.00 50.03  ? 223  GLU B N     1 
ATOM   5096  C CA    . GLU B 1 223 ? -8.358   -67.624  -7.077  1.00 56.42  ? 223  GLU B CA    1 
ATOM   5097  C C     . GLU B 1 223 ? -8.035   -68.096  -8.496  1.00 56.03  ? 223  GLU B C     1 
ATOM   5098  O O     . GLU B 1 223 ? -7.959   -69.308  -8.746  1.00 60.21  ? 223  GLU B O     1 
ATOM   5099  C CB    . GLU B 1 223 ? -7.159   -67.666  -6.126  1.00 62.27  ? 223  GLU B CB    1 
ATOM   5100  C CG    . GLU B 1 223 ? -6.006   -66.795  -6.622  1.00 73.71  ? 223  GLU B CG    1 
ATOM   5101  C CD    . GLU B 1 223 ? -4.912   -66.523  -5.599  1.00 76.70  ? 223  GLU B CD    1 
ATOM   5102  O OE1   . GLU B 1 223 ? -4.978   -67.060  -4.470  1.00 74.62  ? 223  GLU B OE1   1 
ATOM   5103  O OE2   . GLU B 1 223 ? -3.974   -65.787  -5.950  1.00 66.12  ? 223  GLU B OE2   1 
ATOM   5104  N N     . ILE B 1 224 ? -7.859   -67.143  -9.429  1.00 53.79  ? 224  ILE B N     1 
ATOM   5105  C CA    . ILE B 1 224 ? -7.765   -67.466  -10.851 1.00 51.90  ? 224  ILE B CA    1 
ATOM   5106  C C     . ILE B 1 224 ? -6.387   -68.062  -11.169 1.00 50.95  ? 224  ILE B C     1 
ATOM   5107  O O     . ILE B 1 224 ? -5.478   -68.026  -10.350 1.00 46.33  ? 224  ILE B O     1 
ATOM   5108  C CB    . ILE B 1 224 ? -8.031   -66.225  -11.717 1.00 44.33  ? 224  ILE B CB    1 
ATOM   5109  C CG1   . ILE B 1 224 ? -7.079   -65.154  -11.343 1.00 45.23  ? 224  ILE B CG1   1 
ATOM   5110  C CG2   . ILE B 1 224 ? -9.471   -65.721  -11.599 1.00 44.80  ? 224  ILE B CG2   1 
ATOM   5111  C CD1   . ILE B 1 224 ? -6.673   -64.276  -12.498 1.00 59.33  ? 224  ILE B CD1   1 
ATOM   5112  N N     . TYR B 1 225 ? -6.250   -68.602  -12.386 1.00 49.62  ? 225  TYR B N     1 
ATOM   5113  C CA    . TYR B 1 225 ? -5.035   -69.248  -12.866 1.00 54.88  ? 225  TYR B CA    1 
ATOM   5114  C C     . TYR B 1 225 ? -4.064   -68.221  -13.466 1.00 49.98  ? 225  TYR B C     1 
ATOM   5115  O O     . TYR B 1 225 ? -4.445   -67.399  -14.306 1.00 45.82  ? 225  TYR B O     1 
ATOM   5116  C CB    . TYR B 1 225 ? -5.537   -70.224  -13.937 1.00 69.19  ? 225  TYR B CB    1 
ATOM   5117  C CG    . TYR B 1 225 ? -4.447   -70.899  -14.762 1.00 85.46  ? 225  TYR B CG    1 
ATOM   5118  C CD1   . TYR B 1 225 ? -3.536   -71.775  -14.161 1.00 77.60  ? 225  TYR B CD1   1 
ATOM   5119  C CD2   . TYR B 1 225 ? -4.332   -70.657  -16.137 1.00 89.43  ? 225  TYR B CD2   1 
ATOM   5120  C CE1   . TYR B 1 225 ? -2.553   -72.398  -14.915 1.00 85.65  ? 225  TYR B CE1   1 
ATOM   5121  C CE2   . TYR B 1 225 ? -3.341   -71.263  -16.894 1.00 84.62  ? 225  TYR B CE2   1 
ATOM   5122  C CZ    . TYR B 1 225 ? -2.454   -72.136  -16.279 1.00 95.67  ? 225  TYR B CZ    1 
ATOM   5123  O OH    . TYR B 1 225 ? -1.464   -72.725  -17.020 1.00 102.01 ? 225  TYR B OH    1 
ATOM   5124  N N     . HIS B 1 226 ? -2.782   -68.291  -13.089 1.00 42.71  ? 226  HIS B N     1 
ATOM   5125  C CA    . HIS B 1 226 ? -1.840   -67.269  -13.534 1.00 40.77  ? 226  HIS B CA    1 
ATOM   5126  C C     . HIS B 1 226 ? -0.845   -67.756  -14.605 1.00 43.12  ? 226  HIS B C     1 
ATOM   5127  O O     . HIS B 1 226 ? 0.044    -67.013  -14.970 1.00 44.22  ? 226  HIS B O     1 
ATOM   5128  C CB    . HIS B 1 226 ? -1.173   -66.605  -12.325 1.00 37.48  ? 226  HIS B CB    1 
ATOM   5129  C CG    . HIS B 1 226 ? -2.153   -65.840  -11.500 1.00 48.84  ? 226  HIS B CG    1 
ATOM   5130  N ND1   . HIS B 1 226 ? -2.905   -64.819  -12.041 1.00 48.37  ? 226  HIS B ND1   1 
ATOM   5131  C CD2   . HIS B 1 226 ? -2.483   -65.909  -10.201 1.00 42.26  ? 226  HIS B CD2   1 
ATOM   5132  C CE1   . HIS B 1 226 ? -3.679   -64.305  -11.096 1.00 52.08  ? 226  HIS B CE1   1 
ATOM   5133  N NE2   . HIS B 1 226 ? -3.440   -64.945  -9.983  1.00 56.81  ? 226  HIS B NE2   1 
ATOM   5134  N N     . GLY B 1 227 ? -0.990   -68.984  -15.122 1.00 43.41  ? 227  GLY B N     1 
ATOM   5135  C CA    . GLY B 1 227 ? -0.046   -69.605  -16.040 1.00 46.84  ? 227  GLY B CA    1 
ATOM   5136  C C     . GLY B 1 227 ? 0.729    -70.761  -15.386 1.00 56.53  ? 227  GLY B C     1 
ATOM   5137  O O     . GLY B 1 227 ? 0.790    -70.882  -14.150 1.00 46.74  ? 227  GLY B O     1 
ATOM   5138  N N     . ALA B 1 228 ? 1.335    -71.610  -16.246 1.00 64.82  ? 228  ALA B N     1 
ATOM   5139  C CA    . ALA B 1 228 ? 2.178    -72.733  -15.845 1.00 71.60  ? 228  ALA B CA    1 
ATOM   5140  C C     . ALA B 1 228 ? 3.396    -72.204  -15.080 1.00 79.26  ? 228  ALA B C     1 
ATOM   5141  O O     . ALA B 1 228 ? 3.836    -71.087  -15.355 1.00 77.75  ? 228  ALA B O     1 
ATOM   5142  C CB    . ALA B 1 228 ? 2.566    -73.487  -17.111 1.00 70.28  ? 228  ALA B CB    1 
ATOM   5143  N N     . PRO B 1 229 ? 4.005    -72.957  -14.135 1.00 87.31  ? 229  PRO B N     1 
ATOM   5144  C CA    . PRO B 1 229 ? 4.903    -72.351  -13.155 1.00 91.60  ? 229  PRO B CA    1 
ATOM   5145  C C     . PRO B 1 229 ? 6.153    -71.655  -13.703 1.00 94.88  ? 229  PRO B C     1 
ATOM   5146  O O     . PRO B 1 229 ? 6.448    -70.574  -13.173 1.00 101.24 ? 229  PRO B O     1 
ATOM   5147  C CB    . PRO B 1 229 ? 5.086    -73.411  -12.061 1.00 91.60  ? 229  PRO B CB    1 
ATOM   5148  C CG    . PRO B 1 229 ? 4.712    -74.707  -12.745 1.00 84.59  ? 229  PRO B CG    1 
ATOM   5149  C CD    . PRO B 1 229 ? 3.937    -74.420  -13.991 1.00 82.44  ? 229  PRO B CD    1 
ATOM   5150  N N     . ASN B 1 230 ? 6.811    -72.190  -14.751 1.00 68.95  ? 230  ASN B N     1 
ATOM   5151  C CA    . ASN B 1 230 ? 8.025    -71.501  -15.200 1.00 66.50  ? 230  ASN B CA    1 
ATOM   5152  C C     . ASN B 1 230 ? 7.760    -70.361  -16.194 1.00 59.34  ? 230  ASN B C     1 
ATOM   5153  O O     . ASN B 1 230 ? 8.655    -69.880  -16.859 1.00 54.41  ? 230  ASN B O     1 
ATOM   5154  C CB    . ASN B 1 230 ? 9.118    -72.475  -15.598 1.00 73.40  ? 230  ASN B CB    1 
ATOM   5155  C CG    . ASN B 1 230 ? 9.867    -72.951  -14.378 1.00 79.29  ? 230  ASN B CG    1 
ATOM   5156  O OD1   . ASN B 1 230 ? 10.008   -74.167  -14.191 1.00 77.05  ? 230  ASN B OD1   1 
ATOM   5157  N ND2   . ASN B 1 230 ? 10.360   -72.039  -13.543 1.00 71.63  ? 230  ASN B ND2   1 
ATOM   5158  N N     . GLU B 1 231 ? 6.486    -70.058  -16.424 1.00 55.33  ? 231  GLU B N     1 
ATOM   5159  C CA    . GLU B 1 231 ? 6.043    -69.253  -17.561 1.00 44.79  ? 231  GLU B CA    1 
ATOM   5160  C C     . GLU B 1 231 ? 5.590    -67.869  -17.109 1.00 32.56  ? 231  GLU B C     1 
ATOM   5161  O O     . GLU B 1 231 ? 5.535    -67.578  -15.926 1.00 34.99  ? 231  GLU B O     1 
ATOM   5162  C CB    . GLU B 1 231 ? 5.036    -70.049  -18.379 1.00 52.54  ? 231  GLU B CB    1 
ATOM   5163  C CG    . GLU B 1 231 ? 5.654    -71.357  -18.863 1.00 75.10  ? 231  GLU B CG    1 
ATOM   5164  C CD    . GLU B 1 231 ? 4.921    -72.004  -20.004 1.00 86.67  ? 231  GLU B CD    1 
ATOM   5165  O OE1   . GLU B 1 231 ? 5.448    -73.019  -20.502 1.00 92.75  ? 231  GLU B OE1   1 
ATOM   5166  O OE2   . GLU B 1 231 ? 3.838    -71.499  -20.364 1.00 85.91  ? 231  GLU B OE2   1 
ATOM   5167  N N     . LYS B 1 232 ? 5.357    -66.984  -18.080 1.00 29.46  ? 232  LYS B N     1 
ATOM   5168  C CA    . LYS B 1 232 ? 4.920    -65.617  -17.848 1.00 24.77  ? 232  LYS B CA    1 
ATOM   5169  C C     . LYS B 1 232 ? 3.614    -65.650  -17.053 1.00 26.98  ? 232  LYS B C     1 
ATOM   5170  O O     . LYS B 1 232 ? 2.683    -66.417  -17.363 1.00 24.84  ? 232  LYS B O     1 
ATOM   5171  C CB    . LYS B 1 232 ? 4.672    -64.974  -19.213 1.00 21.25  ? 232  LYS B CB    1 
ATOM   5172  C CG    . LYS B 1 232 ? 4.344    -63.500  -19.182 1.00 26.07  ? 232  LYS B CG    1 
ATOM   5173  C CD    . LYS B 1 232 ? 3.576    -63.080  -20.426 1.00 27.47  ? 232  LYS B CD    1 
ATOM   5174  C CE    . LYS B 1 232 ? 3.228    -61.620  -20.448 1.00 24.81  ? 232  LYS B CE    1 
ATOM   5175  N NZ    . LYS B 1 232 ? 2.568    -61.272  -21.707 1.00 24.77  ? 232  LYS B NZ    1 
ATOM   5176  N N     . TYR B 1 233 ? 3.573    -64.831  -15.998 1.00 23.35  ? 233  TYR B N     1 
ATOM   5177  C CA    . TYR B 1 233 ? 2.358    -64.641  -15.229 1.00 23.73  ? 233  TYR B CA    1 
ATOM   5178  C C     . TYR B 1 233 ? 1.328    -63.852  -16.047 1.00 26.02  ? 233  TYR B C     1 
ATOM   5179  O O     . TYR B 1 233 ? 1.612    -62.766  -16.591 1.00 25.61  ? 233  TYR B O     1 
ATOM   5180  C CB    . TYR B 1 233 ? 2.801    -63.735  -14.075 1.00 21.58  ? 233  TYR B CB    1 
ATOM   5181  C CG    . TYR B 1 233 ? 1.668    -63.385  -13.120 1.00 27.74  ? 233  TYR B CG    1 
ATOM   5182  C CD1   . TYR B 1 233 ? 0.804    -62.319  -13.392 1.00 26.13  ? 233  TYR B CD1   1 
ATOM   5183  C CD2   . TYR B 1 233 ? 1.497    -64.082  -11.920 1.00 27.44  ? 233  TYR B CD2   1 
ATOM   5184  C CE1   . TYR B 1 233 ? -0.200   -61.963  -12.500 1.00 25.77  ? 233  TYR B CE1   1 
ATOM   5185  C CE2   . TYR B 1 233 ? 0.517    -63.717  -11.004 1.00 24.57  ? 233  TYR B CE2   1 
ATOM   5186  C CZ    . TYR B 1 233 ? -0.331   -62.653  -11.303 1.00 25.34  ? 233  TYR B CZ    1 
ATOM   5187  O OH    . TYR B 1 233 ? -1.338   -62.291  -10.477 1.00 22.94  ? 233  TYR B OH    1 
ATOM   5188  N N     . VAL B 1 234 ? 0.104    -64.383  -16.086 1.00 25.24  ? 234  VAL B N     1 
ATOM   5189  C CA    . VAL B 1 234 ? -1.008   -63.729  -16.774 1.00 24.73  ? 234  VAL B CA    1 
ATOM   5190  C C     . VAL B 1 234 ? -2.069   -63.341  -15.741 1.00 21.98  ? 234  VAL B C     1 
ATOM   5191  O O     . VAL B 1 234 ? -2.449   -64.152  -14.888 1.00 21.11  ? 234  VAL B O     1 
ATOM   5192  C CB    . VAL B 1 234 ? -1.538   -64.767  -17.776 1.00 26.01  ? 234  VAL B CB    1 
ATOM   5193  C CG1   . VAL B 1 234 ? -2.722   -64.242  -18.515 1.00 26.66  ? 234  VAL B CG1   1 
ATOM   5194  C CG2   . VAL B 1 234 ? -0.468   -65.074  -18.817 1.00 27.78  ? 234  VAL B CG2   1 
ATOM   5195  N N     . ALA B 1 235 ? -2.515   -62.083  -15.804 1.00 19.17  ? 235  ALA B N     1 
ATOM   5196  C CA    . ALA B 1 235 ? -3.534   -61.583  -14.895 1.00 19.65  ? 235  ALA B CA    1 
ATOM   5197  C C     . ALA B 1 235 ? -4.910   -62.059  -15.367 1.00 23.81  ? 235  ALA B C     1 
ATOM   5198  O O     . ALA B 1 235 ? -5.034   -62.698  -16.428 1.00 23.32  ? 235  ALA B O     1 
ATOM   5199  C CB    . ALA B 1 235 ? -3.475   -60.060  -14.832 1.00 17.69  ? 235  ALA B CB    1 
ATOM   5200  N N     . GLY B 1 236 ? -5.949   -61.719  -14.580 1.00 20.49  ? 236  GLY B N     1 
ATOM   5201  C CA    . GLY B 1 236 ? -7.314   -62.102  -14.915 1.00 18.72  ? 236  GLY B CA    1 
ATOM   5202  C C     . GLY B 1 236 ? -8.284   -60.934  -14.752 1.00 19.84  ? 236  GLY B C     1 
ATOM   5203  O O     . GLY B 1 236 ? -8.005   -59.967  -14.030 1.00 19.31  ? 236  GLY B O     1 
ATOM   5204  N N     . GLU B 1 237 ? -9.431   -61.037  -15.425 1.00 19.12  ? 237  GLU B N     1 
ATOM   5205  C CA    . GLU B 1 237 ? -10.426  -59.976  -15.358 1.00 20.58  ? 237  GLU B CA    1 
ATOM   5206  C C     . GLU B 1 237 ? -11.806  -60.617  -15.492 1.00 24.76  ? 237  GLU B C     1 
ATOM   5207  O O     . GLU B 1 237 ? -11.985  -61.550  -16.292 1.00 22.51  ? 237  GLU B O     1 
ATOM   5208  C CB    . GLU B 1 237 ? -10.184  -59.013  -16.518 1.00 17.94  ? 237  GLU B CB    1 
ATOM   5209  C CG    . GLU B 1 237 ? -10.958  -57.713  -16.429 1.00 20.68  ? 237  GLU B CG    1 
ATOM   5210  C CD    . GLU B 1 237 ? -10.776  -56.910  -17.731 1.00 26.98  ? 237  GLU B CD    1 
ATOM   5211  O OE1   . GLU B 1 237 ? -10.073  -55.820  -17.757 1.00 26.38  ? 237  GLU B OE1   1 
ATOM   5212  O OE2   . GLU B 1 237 ? -11.388  -57.386  -18.754 1.00 25.93  ? 237  GLU B OE2   1 
ATOM   5213  N N     . ILE B 1 238 ? -12.761  -60.127  -14.684 1.00 24.42  ? 238  ILE B N     1 
ATOM   5214  C CA    . ILE B 1 238 ? -14.150  -60.501  -14.878 1.00 23.21  ? 238  ILE B CA    1 
ATOM   5215  C C     . ILE B 1 238 ? -14.946  -59.260  -15.289 1.00 22.71  ? 238  ILE B C     1 
ATOM   5216  O O     . ILE B 1 238 ? -14.498  -58.142  -15.107 1.00 22.53  ? 238  ILE B O     1 
ATOM   5217  C CB    . ILE B 1 238 ? -14.733  -61.223  -13.648 1.00 22.92  ? 238  ILE B CB    1 
ATOM   5218  C CG1   . ILE B 1 238 ? -14.952  -60.290  -12.494 1.00 23.98  ? 238  ILE B CG1   1 
ATOM   5219  C CG2   . ILE B 1 238 ? -13.892  -62.428  -13.243 1.00 21.07  ? 238  ILE B CG2   1 
ATOM   5220  C CD1   . ILE B 1 238 ? -15.433  -61.028  -11.254 1.00 29.53  ? 238  ILE B CD1   1 
ATOM   5221  N N     . SER B 1 239 ? -16.140  -59.490  -15.824 1.00 24.31  ? 239  SER B N     1 
ATOM   5222  C CA    . SER B 1 239 ? -17.021  -58.482  -16.395 1.00 28.69  ? 239  SER B CA    1 
ATOM   5223  C C     . SER B 1 239 ? -18.432  -58.654  -15.848 1.00 27.82  ? 239  SER B C     1 
ATOM   5224  O O     . SER B 1 239 ? -18.897  -59.777  -15.677 1.00 33.53  ? 239  SER B O     1 
ATOM   5225  C CB    . SER B 1 239 ? -17.078  -58.692  -17.870 1.00 31.73  ? 239  SER B CB    1 
ATOM   5226  O OG    . SER B 1 239 ? -16.017  -57.945  -18.423 1.00 41.95  ? 239  SER B OG    1 
ATOM   5227  N N     . ILE B 1 240 ? -19.120  -57.544  -15.623 1.00 26.43  ? 240  ILE B N     1 
ATOM   5228  C CA    . ILE B 1 240 ? -20.518  -57.637  -15.260 1.00 25.67  ? 240  ILE B CA    1 
ATOM   5229  C C     . ILE B 1 240 ? -21.263  -56.603  -16.098 1.00 24.99  ? 240  ILE B C     1 
ATOM   5230  O O     . ILE B 1 240 ? -20.818  -55.454  -16.213 1.00 24.80  ? 240  ILE B O     1 
ATOM   5231  C CB    . ILE B 1 240 ? -20.733  -57.491  -13.739 1.00 25.86  ? 240  ILE B CB    1 
ATOM   5232  C CG1   . ILE B 1 240 ? -22.187  -57.740  -13.354 1.00 30.44  ? 240  ILE B CG1   1 
ATOM   5233  C CG2   . ILE B 1 240 ? -20.268  -56.141  -13.191 1.00 21.60  ? 240  ILE B CG2   1 
ATOM   5234  C CD1   . ILE B 1 240 ? -22.475  -57.615  -11.859 1.00 31.79  ? 240  ILE B CD1   1 
ATOM   5235  N N     . THR B 1 241 ? -22.382  -57.035  -16.691 1.00 19.62  ? 241  THR B N     1 
ATOM   5236  C CA    . THR B 1 241 ? -23.267  -56.061  -17.307 1.00 22.67  ? 241  THR B CA    1 
ATOM   5237  C C     . THR B 1 241 ? -24.495  -55.877  -16.395 1.00 21.48  ? 241  THR B C     1 
ATOM   5238  O O     . THR B 1 241 ? -24.812  -56.760  -15.595 1.00 23.18  ? 241  THR B O     1 
ATOM   5239  C CB    . THR B 1 241 ? -23.562  -56.488  -18.761 1.00 24.88  ? 241  THR B CB    1 
ATOM   5240  O OG1   . THR B 1 241 ? -24.155  -55.315  -19.344 1.00 29.08  ? 241  THR B OG1   1 
ATOM   5241  C CG2   . THR B 1 241 ? -24.434  -57.737  -18.810 1.00 21.16  ? 241  THR B CG2   1 
ATOM   5242  N N     . LEU B 1 242 ? -25.171  -54.733  -16.482 1.00 20.48  ? 242  LEU B N     1 
ATOM   5243  C CA    . LEU B 1 242 ? -26.199  -54.396  -15.488 1.00 21.79  ? 242  LEU B CA    1 
ATOM   5244  C C     . LEU B 1 242 ? -27.492  -55.189  -15.692 1.00 22.83  ? 242  LEU B C     1 
ATOM   5245  O O     . LEU B 1 242 ? -28.129  -55.569  -14.717 1.00 23.39  ? 242  LEU B O     1 
ATOM   5246  C CB    . LEU B 1 242 ? -26.478  -52.894  -15.471 1.00 23.24  ? 242  LEU B CB    1 
ATOM   5247  C CG    . LEU B 1 242 ? -25.260  -52.024  -15.113 1.00 23.99  ? 242  LEU B CG    1 
ATOM   5248  C CD1   . LEU B 1 242 ? -25.629  -50.548  -15.224 1.00 21.33  ? 242  LEU B CD1   1 
ATOM   5249  C CD2   . LEU B 1 242 ? -24.570  -52.389  -13.783 1.00 20.55  ? 242  LEU B CD2   1 
ATOM   5250  N N     . ASN B 1 243 ? -27.874  -55.426  -16.955 1.00 22.46  ? 243  ASN B N     1 
ATOM   5251  C CA    . ASN B 1 243 ? -28.980  -56.310  -17.269 1.00 22.66  ? 243  ASN B CA    1 
ATOM   5252  C C     . ASN B 1 243 ? -28.427  -57.518  -18.025 1.00 22.17  ? 243  ASN B C     1 
ATOM   5253  O O     . ASN B 1 243 ? -27.354  -57.980  -17.693 1.00 25.58  ? 243  ASN B O     1 
ATOM   5254  C CB    . ASN B 1 243 ? -30.155  -55.558  -17.880 1.00 20.48  ? 243  ASN B CB    1 
ATOM   5255  C CG    . ASN B 1 243 ? -29.767  -54.816  -19.150 1.00 22.15  ? 243  ASN B CG    1 
ATOM   5256  O OD1   . ASN B 1 243 ? -28.683  -55.048  -19.707 1.00 21.04  ? 243  ASN B OD1   1 
ATOM   5257  N ND2   . ASN B 1 243 ? -30.638  -53.932  -19.636 1.00 23.18  ? 243  ASN B ND2   1 
ATOM   5258  N N     . GLN B 1 244 ? -29.135  -58.013  -19.041 1.00 22.40  ? 244  GLN B N     1 
ATOM   5259  C CA    . GLN B 1 244 ? -28.728  -59.221  -19.744 1.00 22.22  ? 244  GLN B CA    1 
ATOM   5260  C C     . GLN B 1 244 ? -27.906  -58.871  -20.991 1.00 23.78  ? 244  GLN B C     1 
ATOM   5261  O O     . GLN B 1 244 ? -27.334  -59.769  -21.614 1.00 27.94  ? 244  GLN B O     1 
ATOM   5262  C CB    . GLN B 1 244 ? -29.962  -60.039  -20.132 1.00 23.20  ? 244  GLN B CB    1 
ATOM   5263  C CG    . GLN B 1 244 ? -30.671  -60.716  -18.952 1.00 24.61  ? 244  GLN B CG    1 
ATOM   5264  C CD    . GLN B 1 244 ? -29.790  -61.767  -18.325 1.00 28.41  ? 244  GLN B CD    1 
ATOM   5265  O OE1   . GLN B 1 244 ? -29.436  -62.762  -18.967 1.00 33.19  ? 244  GLN B OE1   1 
ATOM   5266  N NE2   . GLN B 1 244 ? -29.357  -61.535  -17.104 1.00 24.88  ? 244  GLN B NE2   1 
ATOM   5267  N N     . HIS B 1 245 ? -27.825  -57.583  -21.369 1.00 21.60  ? 245  HIS B N     1 
ATOM   5268  C CA    . HIS B 1 245 ? -27.227  -57.189  -22.641 1.00 21.90  ? 245  HIS B CA    1 
ATOM   5269  C C     . HIS B 1 245 ? -26.021  -56.273  -22.427 1.00 22.78  ? 245  HIS B C     1 
ATOM   5270  O O     . HIS B 1 245 ? -25.944  -55.615  -21.404 1.00 22.04  ? 245  HIS B O     1 
ATOM   5271  C CB    . HIS B 1 245 ? -28.295  -56.546  -23.538 1.00 23.63  ? 245  HIS B CB    1 
ATOM   5272  C CG    . HIS B 1 245 ? -29.385  -57.510  -23.880 1.00 24.37  ? 245  HIS B CG    1 
ATOM   5273  N ND1   . HIS B 1 245 ? -30.454  -57.760  -23.034 1.00 22.82  ? 245  HIS B ND1   1 
ATOM   5274  C CD2   . HIS B 1 245 ? -29.542  -58.345  -24.947 1.00 22.67  ? 245  HIS B CD2   1 
ATOM   5275  C CE1   . HIS B 1 245 ? -31.244  -58.677  -23.583 1.00 21.22  ? 245  HIS B CE1   1 
ATOM   5276  N NE2   . HIS B 1 245 ? -30.710  -59.055  -24.743 1.00 21.24  ? 245  HIS B NE2   1 
ATOM   5277  N N     . TRP B 1 246 ? -25.100  -56.220  -23.403 1.00 21.74  ? 246  TRP B N     1 
ATOM   5278  C CA    . TRP B 1 246 ? -23.940  -55.351  -23.312 1.00 20.62  ? 246  TRP B CA    1 
ATOM   5279  C C     . TRP B 1 246 ? -24.217  -53.988  -23.950 1.00 20.81  ? 246  TRP B C     1 
ATOM   5280  O O     . TRP B 1 246 ? -23.953  -52.957  -23.331 1.00 20.01  ? 246  TRP B O     1 
ATOM   5281  C CB    . TRP B 1 246 ? -22.715  -56.038  -23.938 1.00 22.42  ? 246  TRP B CB    1 
ATOM   5282  C CG    . TRP B 1 246 ? -22.383  -57.282  -23.161 1.00 26.99  ? 246  TRP B CG    1 
ATOM   5283  C CD1   . TRP B 1 246 ? -22.977  -58.499  -23.311 1.00 29.31  ? 246  TRP B CD1   1 
ATOM   5284  C CD2   . TRP B 1 246 ? -21.488  -57.409  -22.023 1.00 26.68  ? 246  TRP B CD2   1 
ATOM   5285  N NE1   . TRP B 1 246 ? -22.496  -59.385  -22.378 1.00 29.69  ? 246  TRP B NE1   1 
ATOM   5286  C CE2   . TRP B 1 246 ? -21.596  -58.746  -21.562 1.00 32.20  ? 246  TRP B CE2   1 
ATOM   5287  C CE3   . TRP B 1 246 ? -20.602  -56.543  -21.365 1.00 26.56  ? 246  TRP B CE3   1 
ATOM   5288  C CZ2   . TRP B 1 246 ? -20.835  -59.239  -20.491 1.00 29.69  ? 246  TRP B CZ2   1 
ATOM   5289  C CZ3   . TRP B 1 246 ? -19.869  -57.029  -20.301 1.00 24.16  ? 246  TRP B CZ3   1 
ATOM   5290  C CH2   . TRP B 1 246 ? -20.008  -58.347  -19.848 1.00 25.16  ? 246  TRP B CH2   1 
ATOM   5291  N N     . GLY B 1 247 ? -24.723  -53.965  -25.189 1.00 17.05  ? 247  GLY B N     1 
ATOM   5292  C CA    . GLY B 1 247 ? -25.272  -52.726  -25.721 1.00 17.11  ? 247  GLY B CA    1 
ATOM   5293  C C     . GLY B 1 247 ? -26.601  -52.409  -25.031 1.00 18.64  ? 247  GLY B C     1 
ATOM   5294  O O     . GLY B 1 247 ? -27.188  -53.288  -24.406 1.00 20.04  ? 247  GLY B O     1 
ATOM   5295  N N     . ILE B 1 248 ? -27.100  -51.188  -25.198 1.00 17.79  ? 248  ILE B N     1 
ATOM   5296  C CA    . ILE B 1 248 ? -28.343  -50.788  -24.561 1.00 19.94  ? 248  ILE B CA    1 
ATOM   5297  C C     . ILE B 1 248 ? -29.504  -51.633  -25.098 1.00 19.73  ? 248  ILE B C     1 
ATOM   5298  O O     . ILE B 1 248 ? -29.543  -52.036  -26.261 1.00 18.62  ? 248  ILE B O     1 
ATOM   5299  C CB    . ILE B 1 248 ? -28.543  -49.273  -24.801 1.00 22.62  ? 248  ILE B CB    1 
ATOM   5300  C CG1   . ILE B 1 248 ? -29.718  -48.708  -23.975 1.00 18.88  ? 248  ILE B CG1   1 
ATOM   5301  C CG2   . ILE B 1 248 ? -28.685  -48.978  -26.305 1.00 19.03  ? 248  ILE B CG2   1 
ATOM   5302  C CD1   . ILE B 1 248 ? -29.722  -47.179  -23.945 1.00 19.90  ? 248  ILE B CD1   1 
ATOM   5303  N N     . ALA B 1 249 ? -30.460  -51.914  -24.217 1.00 22.01  ? 249  ALA B N     1 
ATOM   5304  C CA    . ALA B 1 249 ? -31.619  -52.744  -24.505 1.00 21.78  ? 249  ALA B CA    1 
ATOM   5305  C C     . ALA B 1 249 ? -32.789  -52.225  -23.666 1.00 23.13  ? 249  ALA B C     1 
ATOM   5306  O O     . ALA B 1 249 ? -32.927  -52.570  -22.498 1.00 23.46  ? 249  ALA B O     1 
ATOM   5307  C CB    . ALA B 1 249 ? -31.314  -54.194  -24.205 1.00 20.30  ? 249  ALA B CB    1 
ATOM   5308  N N     . ALA B 1 250 ? -33.639  -51.420  -24.313 1.00 21.54  ? 250  ALA B N     1 
ATOM   5309  C CA    . ALA B 1 250 ? -34.659  -50.617  -23.667 1.00 21.55  ? 250  ALA B CA    1 
ATOM   5310  C C     . ALA B 1 250 ? -35.658  -51.499  -22.929 1.00 23.19  ? 250  ALA B C     1 
ATOM   5311  O O     . ALA B 1 250 ? -36.123  -51.099  -21.865 1.00 25.49  ? 250  ALA B O     1 
ATOM   5312  C CB    . ALA B 1 250 ? -35.367  -49.712  -24.687 1.00 19.22  ? 250  ALA B CB    1 
ATOM   5313  N N     . ASN B 1 251 ? -36.026  -52.665  -23.490 1.00 22.17  ? 251  ASN B N     1 
ATOM   5314  C CA    . ASN B 1 251 ? -37.015  -53.504  -22.816 1.00 21.44  ? 251  ASN B CA    1 
ATOM   5315  C C     . ASN B 1 251 ? -36.391  -54.705  -22.113 1.00 21.27  ? 251  ASN B C     1 
ATOM   5316  O O     . ASN B 1 251 ? -37.069  -55.732  -21.897 1.00 19.37  ? 251  ASN B O     1 
ATOM   5317  C CB    . ASN B 1 251 ? -38.144  -53.921  -23.750 1.00 21.64  ? 251  ASN B CB    1 
ATOM   5318  C CG    . ASN B 1 251 ? -38.962  -52.717  -24.166 1.00 25.14  ? 251  ASN B CG    1 
ATOM   5319  O OD1   . ASN B 1 251 ? -39.309  -51.814  -23.375 1.00 28.56  ? 251  ASN B OD1   1 
ATOM   5320  N ND2   . ASN B 1 251 ? -39.268  -52.690  -25.440 1.00 29.22  ? 251  ASN B ND2   1 
ATOM   5321  N N     . ASP B 1 252 ? -35.094  -54.596  -21.784 1.00 18.30  ? 252  ASP B N     1 
ATOM   5322  C CA    . ASP B 1 252 ? -34.506  -55.552  -20.849 1.00 18.73  ? 252  ASP B CA    1 
ATOM   5323  C C     . ASP B 1 252 ? -34.636  -54.945  -19.438 1.00 20.31  ? 252  ASP B C     1 
ATOM   5324  O O     . ASP B 1 252 ? -33.865  -54.038  -19.080 1.00 19.26  ? 252  ASP B O     1 
ATOM   5325  C CB    . ASP B 1 252 ? -33.076  -55.877  -21.256 1.00 15.34  ? 252  ASP B CB    1 
ATOM   5326  C CG    . ASP B 1 252 ? -32.319  -56.756  -20.277 1.00 18.17  ? 252  ASP B CG    1 
ATOM   5327  O OD1   . ASP B 1 252 ? -32.924  -57.098  -19.211 1.00 18.83  ? 252  ASP B OD1   1 
ATOM   5328  O OD2   . ASP B 1 252 ? -31.136  -57.111  -20.562 1.00 18.43  ? 252  ASP B OD2   1 
ATOM   5329  N N     . LEU B 1 253 ? -35.629  -55.417  -18.671 1.00 17.22  ? 253  LEU B N     1 
ATOM   5330  C CA    . LEU B 1 253 ? -35.908  -54.946  -17.326 1.00 17.77  ? 253  LEU B CA    1 
ATOM   5331  C C     . LEU B 1 253 ? -35.166  -55.796  -16.296 1.00 19.86  ? 253  LEU B C     1 
ATOM   5332  O O     . LEU B 1 253 ? -35.290  -55.566  -15.094 1.00 21.41  ? 253  LEU B O     1 
ATOM   5333  C CB    . LEU B 1 253 ? -37.419  -55.049  -17.101 1.00 18.27  ? 253  LEU B CB    1 
ATOM   5334  C CG    . LEU B 1 253 ? -38.305  -54.388  -18.176 1.00 20.26  ? 253  LEU B CG    1 
ATOM   5335  C CD1   . LEU B 1 253 ? -39.730  -54.315  -17.639 1.00 17.54  ? 253  LEU B CD1   1 
ATOM   5336  C CD2   . LEU B 1 253 ? -37.804  -53.005  -18.640 1.00 16.03  ? 253  LEU B CD2   1 
ATOM   5337  N N     . ASN B 1 254 ? -34.438  -56.825  -16.755 1.00 19.19  ? 254  ASN B N     1 
ATOM   5338  C CA    . ASN B 1 254 ? -33.857  -57.780  -15.821 1.00 20.08  ? 254  ASN B CA    1 
ATOM   5339  C C     . ASN B 1 254 ? -32.512  -57.272  -15.265 1.00 19.24  ? 254  ASN B C     1 
ATOM   5340  O O     . ASN B 1 254 ? -31.467  -57.874  -15.512 1.00 17.63  ? 254  ASN B O     1 
ATOM   5341  C CB    . ASN B 1 254 ? -33.779  -59.146  -16.494 1.00 20.99  ? 254  ASN B CB    1 
ATOM   5342  C CG    . ASN B 1 254 ? -33.396  -60.243  -15.523 1.00 23.55  ? 254  ASN B CG    1 
ATOM   5343  O OD1   . ASN B 1 254 ? -33.386  -60.043  -14.301 1.00 23.79  ? 254  ASN B OD1   1 
ATOM   5344  N ND2   . ASN B 1 254 ? -33.026  -61.404  -16.050 1.00 20.79  ? 254  ASN B ND2   1 
ATOM   5345  N N     . TYR B 1 255 ? -32.530  -56.142  -14.546 1.00 19.62  ? 255  TYR B N     1 
ATOM   5346  C CA    . TYR B 1 255 ? -31.323  -55.571  -13.951 1.00 19.37  ? 255  TYR B CA    1 
ATOM   5347  C C     . TYR B 1 255 ? -30.922  -56.326  -12.686 1.00 18.93  ? 255  TYR B C     1 
ATOM   5348  O O     . TYR B 1 255 ? -31.783  -56.788  -11.953 1.00 20.00  ? 255  TYR B O     1 
ATOM   5349  C CB    . TYR B 1 255 ? -31.613  -54.116  -13.575 1.00 17.68  ? 255  TYR B CB    1 
ATOM   5350  C CG    . TYR B 1 255 ? -31.419  -53.192  -14.766 1.00 19.35  ? 255  TYR B CG    1 
ATOM   5351  C CD1   . TYR B 1 255 ? -32.385  -53.108  -15.778 1.00 18.86  ? 255  TYR B CD1   1 
ATOM   5352  C CD2   . TYR B 1 255 ? -30.267  -52.415  -14.887 1.00 20.01  ? 255  TYR B CD2   1 
ATOM   5353  C CE1   . TYR B 1 255 ? -32.214  -52.264  -16.870 1.00 17.06  ? 255  TYR B CE1   1 
ATOM   5354  C CE2   . TYR B 1 255 ? -30.064  -51.598  -16.000 1.00 19.53  ? 255  TYR B CE2   1 
ATOM   5355  C CZ    . TYR B 1 255 ? -31.054  -51.520  -16.970 1.00 17.80  ? 255  TYR B CZ    1 
ATOM   5356  O OH    . TYR B 1 255 ? -30.910  -50.715  -18.035 1.00 19.45  ? 255  TYR B OH    1 
ATOM   5357  N N     . LYS B 1 256 ? -29.617  -56.478  -12.451 1.00 21.57  ? 256  LYS B N     1 
ATOM   5358  C CA    . LYS B 1 256 ? -29.101  -57.046  -11.207 1.00 21.77  ? 256  LYS B CA    1 
ATOM   5359  C C     . LYS B 1 256 ? -29.244  -55.982  -10.109 1.00 23.44  ? 256  LYS B C     1 
ATOM   5360  O O     . LYS B 1 256 ? -29.362  -54.793  -10.413 1.00 22.19  ? 256  LYS B O     1 
ATOM   5361  C CB    . LYS B 1 256 ? -27.623  -57.360  -11.434 1.00 21.66  ? 256  LYS B CB    1 
ATOM   5362  C CG    . LYS B 1 256 ? -27.403  -58.403  -12.504 1.00 23.73  ? 256  LYS B CG    1 
ATOM   5363  C CD    . LYS B 1 256 ? -25.934  -58.600  -12.874 1.00 26.27  ? 256  LYS B CD    1 
ATOM   5364  C CE    . LYS B 1 256 ? -25.731  -59.537  -14.053 1.00 27.07  ? 256  LYS B CE    1 
ATOM   5365  N NZ    . LYS B 1 256 ? -26.522  -59.069  -15.218 1.00 25.57  ? 256  LYS B NZ    1 
ATOM   5366  N N     . SER B 1 257 ? -29.265  -56.398  -8.841  1.00 20.87  ? 257  SER B N     1 
ATOM   5367  C CA    . SER B 1 257 ? -29.324  -55.400  -7.783  1.00 20.95  ? 257  SER B CA    1 
ATOM   5368  C C     . SER B 1 257 ? -27.992  -54.665  -7.664  1.00 21.97  ? 257  SER B C     1 
ATOM   5369  O O     . SER B 1 257 ? -26.925  -55.251  -7.917  1.00 18.15  ? 257  SER B O     1 
ATOM   5370  C CB    . SER B 1 257 ? -29.663  -56.033  -6.448  1.00 19.55  ? 257  SER B CB    1 
ATOM   5371  O OG    . SER B 1 257 ? -28.591  -56.832  -6.017  1.00 19.57  ? 257  SER B OG    1 
ATOM   5372  N N     . PRO B 1 258 ? -28.012  -53.376  -7.255  1.00 19.36  ? 258  PRO B N     1 
ATOM   5373  C CA    . PRO B 1 258 ? -26.776  -52.690  -6.877  1.00 17.71  ? 258  PRO B CA    1 
ATOM   5374  C C     . PRO B 1 258 ? -25.946  -53.486  -5.870  1.00 18.49  ? 258  PRO B C     1 
ATOM   5375  O O     . PRO B 1 258 ? -24.715  -53.499  -5.933  1.00 21.71  ? 258  PRO B O     1 
ATOM   5376  C CB    . PRO B 1 258 ? -27.253  -51.301  -6.444  1.00 18.20  ? 258  PRO B CB    1 
ATOM   5377  C CG    . PRO B 1 258 ? -28.581  -51.136  -7.219  1.00 18.43  ? 258  PRO B CG    1 
ATOM   5378  C CD    . PRO B 1 258 ? -29.201  -52.515  -7.235  1.00 17.94  ? 258  PRO B CD    1 
ATOM   5379  N N     . ALA B 1 259 ? -26.618  -54.226  -4.980  1.00 17.86  ? 259  ALA B N     1 
ATOM   5380  C CA    . ALA B 1 259 ? -25.924  -55.015  -3.976  1.00 20.15  ? 259  ALA B CA    1 
ATOM   5381  C C     . ALA B 1 259 ? -25.093  -56.109  -4.649  1.00 21.82  ? 259  ALA B C     1 
ATOM   5382  O O     . ALA B 1 259 ? -23.944  -56.349  -4.275  1.00 22.88  ? 259  ALA B O     1 
ATOM   5383  C CB    . ALA B 1 259 ? -26.907  -55.603  -2.965  1.00 16.64  ? 259  ALA B CB    1 
ATOM   5384  N N     . GLU B 1 260 ? -25.687  -56.783  -5.643  1.00 22.49  ? 260  GLU B N     1 
ATOM   5385  C CA    . GLU B 1 260 ? -24.980  -57.844  -6.344  1.00 24.82  ? 260  GLU B CA    1 
ATOM   5386  C C     . GLU B 1 260 ? -23.771  -57.238  -7.073  1.00 22.23  ? 260  GLU B C     1 
ATOM   5387  O O     . GLU B 1 260 ? -22.704  -57.836  -7.135  1.00 23.22  ? 260  GLU B O     1 
ATOM   5388  C CB    . GLU B 1 260 ? -25.926  -58.618  -7.254  1.00 22.90  ? 260  GLU B CB    1 
ATOM   5389  C CG    . GLU B 1 260 ? -25.176  -59.620  -8.124  1.00 32.23  ? 260  GLU B CG    1 
ATOM   5390  C CD    . GLU B 1 260 ? -25.983  -60.488  -9.089  1.00 41.59  ? 260  GLU B CD    1 
ATOM   5391  O OE1   . GLU B 1 260 ? -27.226  -60.465  -9.090  1.00 42.02  ? 260  GLU B OE1   1 
ATOM   5392  O OE2   . GLU B 1 260 ? -25.347  -61.195  -9.881  1.00 47.05  ? 260  GLU B OE2   1 
ATOM   5393  N N     . MET B 1 261 ? -23.934  -56.038  -7.620  1.00 18.14  ? 261  MET B N     1 
ATOM   5394  C CA    . MET B 1 261 ? -22.841  -55.361  -8.287  1.00 20.73  ? 261  MET B CA    1 
ATOM   5395  C C     . MET B 1 261 ? -21.679  -55.138  -7.305  1.00 21.85  ? 261  MET B C     1 
ATOM   5396  O O     . MET B 1 261 ? -20.531  -55.480  -7.619  1.00 19.47  ? 261  MET B O     1 
ATOM   5397  C CB    . MET B 1 261 ? -23.340  -54.067  -8.938  1.00 22.36  ? 261  MET B CB    1 
ATOM   5398  C CG    . MET B 1 261 ? -22.228  -53.180  -9.469  1.00 22.43  ? 261  MET B CG    1 
ATOM   5399  S SD    . MET B 1 261 ? -22.804  -51.531  -9.973  1.00 28.71  ? 261  MET B SD    1 
ATOM   5400  C CE    . MET B 1 261 ? -23.458  -50.871  -8.429  1.00 24.35  ? 261  MET B CE    1 
ATOM   5401  N N     . ILE B 1 262 ? -21.981  -54.608  -6.098  1.00 19.88  ? 262  ILE B N     1 
ATOM   5402  C CA    . ILE B 1 262 ? -20.946  -54.405  -5.101  1.00 18.16  ? 262  ILE B CA    1 
ATOM   5403  C C     . ILE B 1 262 ? -20.286  -55.729  -4.703  1.00 17.97  ? 262  ILE B C     1 
ATOM   5404  O O     . ILE B 1 262 ? -19.059  -55.812  -4.644  1.00 16.85  ? 262  ILE B O     1 
ATOM   5405  C CB    . ILE B 1 262 ? -21.469  -53.610  -3.894  1.00 19.11  ? 262  ILE B CB    1 
ATOM   5406  C CG1   . ILE B 1 262 ? -21.728  -52.177  -4.293  1.00 16.39  ? 262  ILE B CG1   1 
ATOM   5407  C CG2   . ILE B 1 262 ? -20.489  -53.690  -2.714  1.00 16.78  ? 262  ILE B CG2   1 
ATOM   5408  C CD1   . ILE B 1 262 ? -22.666  -51.437  -3.363  1.00 16.94  ? 262  ILE B CD1   1 
ATOM   5409  N N     . GLU B 1 263 ? -21.083  -56.769  -4.474  1.00 17.91  ? 263  GLU B N     1 
ATOM   5410  C CA    . GLU B 1 263 ? -20.530  -58.064  -4.133  1.00 20.31  ? 263  GLU B CA    1 
ATOM   5411  C C     . GLU B 1 263 ? -19.618  -58.612  -5.240  1.00 23.37  ? 263  GLU B C     1 
ATOM   5412  O O     . GLU B 1 263 ? -18.621  -59.286  -4.934  1.00 23.74  ? 263  GLU B O     1 
ATOM   5413  C CB    . GLU B 1 263 ? -21.600  -59.090  -3.785  1.00 22.46  ? 263  GLU B CB    1 
ATOM   5414  C CG    . GLU B 1 263 ? -22.343  -58.763  -2.493  1.00 26.77  ? 263  GLU B CG    1 
ATOM   5415  C CD    . GLU B 1 263 ? -23.261  -59.875  -1.969  1.00 33.25  ? 263  GLU B CD    1 
ATOM   5416  O OE1   . GLU B 1 263 ? -23.294  -60.962  -2.608  1.00 33.83  ? 263  GLU B OE1   1 
ATOM   5417  O OE2   . GLU B 1 263 ? -23.944  -59.692  -0.909  1.00 34.74  ? 263  GLU B OE2   1 
ATOM   5418  N N     . THR B 1 264 ? -19.927  -58.316  -6.511  1.00 20.56  ? 264  THR B N     1 
ATOM   5419  C CA    . THR B 1 264 ? -19.151  -58.869  -7.612  1.00 20.68  ? 264  THR B CA    1 
ATOM   5420  C C     . THR B 1 264 ? -17.808  -58.138  -7.674  1.00 19.76  ? 264  THR B C     1 
ATOM   5421  O O     . THR B 1 264 ? -16.769  -58.763  -7.922  1.00 20.57  ? 264  THR B O     1 
ATOM   5422  C CB    . THR B 1 264 ? -19.902  -58.751  -8.945  1.00 21.95  ? 264  THR B CB    1 
ATOM   5423  O OG1   . THR B 1 264 ? -21.150  -59.380  -8.706  1.00 22.68  ? 264  THR B OG1   1 
ATOM   5424  C CG2   . THR B 1 264 ? -19.209  -59.490  -10.075 1.00 20.47  ? 264  THR B CG2   1 
ATOM   5425  N N     . VAL B 1 265 ? -17.826  -56.820  -7.443  1.00 18.13  ? 265  VAL B N     1 
ATOM   5426  C CA    . VAL B 1 265 ? -16.578  -56.070  -7.411  1.00 17.67  ? 265  VAL B CA    1 
ATOM   5427  C C     . VAL B 1 265 ? -15.688  -56.631  -6.301  1.00 20.00  ? 265  VAL B C     1 
ATOM   5428  O O     . VAL B 1 265 ? -14.516  -56.949  -6.540  1.00 20.87  ? 265  VAL B O     1 
ATOM   5429  C CB    . VAL B 1 265 ? -16.834  -54.569  -7.249  1.00 17.17  ? 265  VAL B CB    1 
ATOM   5430  C CG1   . VAL B 1 265 ? -15.552  -53.811  -6.917  1.00 17.20  ? 265  VAL B CG1   1 
ATOM   5431  C CG2   . VAL B 1 265 ? -17.559  -53.992  -8.464  1.00 14.29  ? 265  VAL B CG2   1 
ATOM   5432  N N     . ALA B 1 266 ? -16.243  -56.815  -5.096  1.00 19.10  ? 266  ALA B N     1 
ATOM   5433  C CA    . ALA B 1 266 ? -15.425  -57.334  -4.003  1.00 20.00  ? 266  ALA B CA    1 
ATOM   5434  C C     . ALA B 1 266 ? -14.902  -58.727  -4.363  1.00 21.45  ? 266  ALA B C     1 
ATOM   5435  O O     . ALA B 1 266 ? -13.752  -59.074  -4.083  1.00 23.15  ? 266  ALA B O     1 
ATOM   5436  C CB    . ALA B 1 266 ? -16.231  -57.350  -2.725  1.00 18.55  ? 266  ALA B CB    1 
ATOM   5437  N N     . HIS B 1 267 ? -15.723  -59.544  -4.971  1.00 21.93  ? 267  HIS B N     1 
ATOM   5438  C CA    . HIS B 1 267 ? -15.375  -60.895  -5.346  1.00 22.85  ? 267  HIS B CA    1 
ATOM   5439  C C     . HIS B 1 267 ? -14.217  -61.042  -6.334  1.00 22.92  ? 267  HIS B C     1 
ATOM   5440  O O     . HIS B 1 267 ? -13.447  -61.943  -6.224  1.00 23.83  ? 267  HIS B O     1 
ATOM   5441  C CB    . HIS B 1 267 ? -16.617  -61.639  -5.790  1.00 20.63  ? 267  HIS B CB    1 
ATOM   5442  C CG    . HIS B 1 267 ? -16.352  -63.008  -6.289  1.00 22.73  ? 267  HIS B CG    1 
ATOM   5443  N ND1   . HIS B 1 267 ? -16.132  -64.070  -5.459  1.00 25.01  ? 267  HIS B ND1   1 
ATOM   5444  C CD2   . HIS B 1 267 ? -16.266  -63.486  -7.539  1.00 22.77  ? 267  HIS B CD2   1 
ATOM   5445  C CE1   . HIS B 1 267 ? -15.907  -65.141  -6.176  1.00 22.81  ? 267  HIS B CE1   1 
ATOM   5446  N NE2   . HIS B 1 267 ? -15.989  -64.813  -7.441  1.00 23.04  ? 267  HIS B NE2   1 
ATOM   5447  N N     . ALA B 1 268 ? -14.128  -60.135  -7.287  1.00 19.94  ? 268  ALA B N     1 
ATOM   5448  C CA    . ALA B 1 268 ? -13.068  -60.110  -8.253  1.00 18.94  ? 268  ALA B CA    1 
ATOM   5449  C C     . ALA B 1 268 ? -11.757  -59.902  -7.555  1.00 20.91  ? 268  ALA B C     1 
ATOM   5450  O O     . ALA B 1 268 ? -10.827  -60.568  -7.828  1.00 19.73  ? 268  ALA B O     1 
ATOM   5451  C CB    . ALA B 1 268 ? -13.285  -59.009  -9.265  1.00 18.35  ? 268  ALA B CB    1 
ATOM   5452  N N     . ARG B 1 269 ? -11.729  -58.983  -6.616  1.00 18.81  ? 269  ARG B N     1 
ATOM   5453  C CA    . ARG B 1 269 ? -10.558  -58.690  -5.840  1.00 19.21  ? 269  ARG B CA    1 
ATOM   5454  C C     . ARG B 1 269 ? -10.134  -59.882  -4.971  1.00 21.79  ? 269  ARG B C     1 
ATOM   5455  O O     . ARG B 1 269 ? -8.995   -60.178  -4.796  1.00 22.71  ? 269  ARG B O     1 
ATOM   5456  C CB    . ARG B 1 269 ? -10.757  -57.417  -5.048  1.00 17.61  ? 269  ARG B CB    1 
ATOM   5457  C CG    . ARG B 1 269 ? -11.062  -56.200  -5.875  1.00 17.93  ? 269  ARG B CG    1 
ATOM   5458  C CD    . ARG B 1 269 ? -10.247  -56.065  -7.117  1.00 16.16  ? 269  ARG B CD    1 
ATOM   5459  N NE    . ARG B 1 269 ? -8.974   -55.462  -6.888  1.00 19.27  ? 269  ARG B NE    1 
ATOM   5460  C CZ    . ARG B 1 269 ? -7.937   -55.532  -7.680  1.00 19.60  ? 269  ARG B CZ    1 
ATOM   5461  N NH1   . ARG B 1 269 ? -7.964   -56.199  -8.768  1.00 17.19  ? 269  ARG B NH1   1 
ATOM   5462  N NH2   . ARG B 1 269 ? -6.881   -54.901  -7.360  1.00 18.77  ? 269  ARG B NH2   1 
ATOM   5463  N N     . HIS B 1 270 ? -11.108  -60.562  -4.445  1.00 19.80  ? 270  HIS B N     1 
ATOM   5464  C CA    . HIS B 1 270 ? -10.901  -61.729  -3.675  1.00 19.72  ? 270  HIS B CA    1 
ATOM   5465  C C     . HIS B 1 270 ? -10.259  -62.876  -4.468  1.00 21.19  ? 270  HIS B C     1 
ATOM   5466  O O     . HIS B 1 270 ? -9.460   -63.578  -3.945  1.00 18.90  ? 270  HIS B O     1 
ATOM   5467  C CB    . HIS B 1 270 ? -12.215  -62.137  -3.049  1.00 23.01  ? 270  HIS B CB    1 
ATOM   5468  C CG    . HIS B 1 270 ? -12.146  -63.397  -2.268  1.00 29.16  ? 270  HIS B CG    1 
ATOM   5469  N ND1   . HIS B 1 270 ? -13.152  -64.318  -2.267  1.00 35.03  ? 270  HIS B ND1   1 
ATOM   5470  C CD2   . HIS B 1 270 ? -11.186  -63.898  -1.470  1.00 25.69  ? 270  HIS B CD2   1 
ATOM   5471  C CE1   . HIS B 1 270 ? -12.817  -65.329  -1.502  1.00 29.23  ? 270  HIS B CE1   1 
ATOM   5472  N NE2   . HIS B 1 270 ? -11.626  -65.100  -1.011  1.00 28.66  ? 270  HIS B NE2   1 
ATOM   5473  N N     . ILE B 1 271 ? -10.621  -63.053  -5.729  1.00 20.92  ? 271  ILE B N     1 
ATOM   5474  C CA    . ILE B 1 271 ? -10.048  -64.142  -6.516  1.00 21.28  ? 271  ILE B CA    1 
ATOM   5475  C C     . ILE B 1 271 ? -8.818   -63.652  -7.293  1.00 25.35  ? 271  ILE B C     1 
ATOM   5476  O O     . ILE B 1 271 ? -8.251   -64.407  -8.086  1.00 26.28  ? 271  ILE B O     1 
ATOM   5477  C CB    . ILE B 1 271 ? -11.076  -64.795  -7.463  1.00 21.20  ? 271  ILE B CB    1 
ATOM   5478  C CG1   . ILE B 1 271 ? -11.573  -63.811  -8.528  1.00 21.35  ? 271  ILE B CG1   1 
ATOM   5479  C CG2   . ILE B 1 271 ? -12.240  -65.422  -6.687  1.00 22.87  ? 271  ILE B CG2   1 
ATOM   5480  C CD1   . ILE B 1 271 ? -12.469  -64.428  -9.597  1.00 21.84  ? 271  ILE B CD1   1 
ATOM   5481  N N     . GLY B 1 272 ? -8.419   -62.387  -7.113  1.00 23.69  ? 272  GLY B N     1 
ATOM   5482  C CA    . GLY B 1 272 ? -7.204   -61.888  -7.742  1.00 25.50  ? 272  GLY B CA    1 
ATOM   5483  C C     . GLY B 1 272 ? -7.402   -61.450  -9.198  1.00 28.03  ? 272  GLY B C     1 
ATOM   5484  O O     . GLY B 1 272 ? -6.523   -61.694  -10.028 1.00 26.39  ? 272  GLY B O     1 
ATOM   5485  N N     . ALA B 1 273 ? -8.527   -60.762  -9.485  1.00 24.15  ? 273  ALA B N     1 
ATOM   5486  C CA    . ALA B 1 273 ? -8.847   -60.308  -10.830 1.00 21.35  ? 273  ALA B CA    1 
ATOM   5487  C C     . ALA B 1 273 ? -9.246   -58.840  -10.774 1.00 21.87  ? 273  ALA B C     1 
ATOM   5488  O O     . ALA B 1 273 ? -9.614   -58.332  -9.718  1.00 21.68  ? 273  ALA B O     1 
ATOM   5489  C CB    . ALA B 1 273 ? -9.982   -61.138  -11.410 1.00 20.62  ? 273  ALA B CB    1 
ATOM   5490  N N     . ASN B 1 274 ? -9.245   -58.222  -11.918 1.00 19.84  ? 274  ASN B N     1 
ATOM   5491  C CA    . ASN B 1 274 ? -9.792   -56.926  -12.102 1.00 17.30  ? 274  ASN B CA    1 
ATOM   5492  C C     . ASN B 1 274 ? -11.287  -57.142  -12.471 1.00 17.79  ? 274  ASN B C     1 
ATOM   5493  O O     . ASN B 1 274 ? -11.712  -58.209  -12.779 1.00 16.52  ? 274  ASN B O     1 
ATOM   5494  C CB    . ASN B 1 274 ? -9.054   -56.171  -13.191 1.00 18.38  ? 274  ASN B CB    1 
ATOM   5495  C CG    . ASN B 1 274 ? -7.819   -55.489  -12.706 1.00 19.74  ? 274  ASN B CG    1 
ATOM   5496  O OD1   . ASN B 1 274 ? -7.242   -55.839  -11.733 1.00 21.28  ? 274  ASN B OD1   1 
ATOM   5497  N ND2   . ASN B 1 274 ? -7.406   -54.538  -13.422 1.00 19.80  ? 274  ASN B ND2   1 
ATOM   5498  N N     . ILE B 1 275 ? -12.076  -56.111  -12.349 1.00 15.91  ? 275  ILE B N     1 
ATOM   5499  C CA    . ILE B 1 275 ? -13.470  -56.146  -12.676 1.00 18.58  ? 275  ILE B CA    1 
ATOM   5500  C C     . ILE B 1 275 ? -13.832  -54.981  -13.591 1.00 20.15  ? 275  ILE B C     1 
ATOM   5501  O O     . ILE B 1 275 ? -13.391  -53.908  -13.382 1.00 19.65  ? 275  ILE B O     1 
ATOM   5502  C CB    . ILE B 1 275 ? -14.349  -56.138  -11.396 1.00 19.31  ? 275  ILE B CB    1 
ATOM   5503  C CG1   . ILE B 1 275 ? -15.824  -56.016  -11.701 1.00 19.44  ? 275  ILE B CG1   1 
ATOM   5504  C CG2   . ILE B 1 275 ? -14.000  -55.003  -10.478 1.00 18.59  ? 275  ILE B CG2   1 
ATOM   5505  C CD1   . ILE B 1 275 ? -16.520  -57.303  -11.873 1.00 26.09  ? 275  ILE B CD1   1 
ATOM   5506  N N     . LEU B 1 276 ? -14.624  -55.240  -14.609 1.00 20.23  ? 276  LEU B N     1 
ATOM   5507  C CA    . LEU B 1 276 ? -15.140  -54.253  -15.501 1.00 21.14  ? 276  LEU B CA    1 
ATOM   5508  C C     . LEU B 1 276 ? -16.639  -54.214  -15.343 1.00 21.83  ? 276  LEU B C     1 
ATOM   5509  O O     . LEU B 1 276 ? -17.254  -55.210  -15.385 1.00 23.21  ? 276  LEU B O     1 
ATOM   5510  C CB    . LEU B 1 276 ? -14.842  -54.626  -16.938 1.00 22.17  ? 276  LEU B CB    1 
ATOM   5511  C CG    . LEU B 1 276 ? -13.447  -54.556  -17.496 1.00 23.48  ? 276  LEU B CG    1 
ATOM   5512  C CD1   . LEU B 1 276 ? -13.484  -54.867  -18.968 1.00 21.12  ? 276  LEU B CD1   1 
ATOM   5513  C CD2   . LEU B 1 276 ? -12.890  -53.181  -17.272 1.00 22.87  ? 276  LEU B CD2   1 
ATOM   5514  N N     . VAL B 1 277 ? -17.188  -53.045  -15.108 1.00 20.31  ? 277  VAL B N     1 
ATOM   5515  C CA    . VAL B 1 277 ? -18.621  -52.839  -15.025 1.00 18.98  ? 277  VAL B CA    1 
ATOM   5516  C C     . VAL B 1 277 ? -19.049  -52.183  -16.335 1.00 21.17  ? 277  VAL B C     1 
ATOM   5517  O O     . VAL B 1 277 ? -18.523  -51.148  -16.717 1.00 21.02  ? 277  VAL B O     1 
ATOM   5518  C CB    . VAL B 1 277 ? -18.928  -51.935  -13.805 1.00 19.62  ? 277  VAL B CB    1 
ATOM   5519  C CG1   . VAL B 1 277 ? -20.386  -51.472  -13.733 1.00 16.73  ? 277  VAL B CG1   1 
ATOM   5520  C CG2   . VAL B 1 277 ? -18.549  -52.650  -12.502 1.00 16.82  ? 277  VAL B CG2   1 
ATOM   5521  N N     . ASN B 1 278 ? -20.015  -52.796  -17.015 1.00 19.79  ? 278  ASN B N     1 
ATOM   5522  C CA    . ASN B 1 278 ? -20.354  -52.416  -18.375 1.00 20.91  ? 278  ASN B CA    1 
ATOM   5523  C C     . ASN B 1 278 ? -21.541  -51.469  -18.394 1.00 22.72  ? 278  ASN B C     1 
ATOM   5524  O O     . ASN B 1 278 ? -22.530  -51.697  -17.688 1.00 23.29  ? 278  ASN B O     1 
ATOM   5525  C CB    . ASN B 1 278 ? -20.757  -53.618  -19.222 1.00 20.13  ? 278  ASN B CB    1 
ATOM   5526  C CG    . ASN B 1 278 ? -21.139  -53.148  -20.599 1.00 22.49  ? 278  ASN B CG    1 
ATOM   5527  O OD1   . ASN B 1 278 ? -20.280  -52.625  -21.329 1.00 26.50  ? 278  ASN B OD1   1 
ATOM   5528  N ND2   . ASN B 1 278 ? -22.416  -53.269  -20.951 1.00 18.99  ? 278  ASN B ND2   1 
ATOM   5529  N N     . ILE B 1 279 ? -21.453  -50.426  -19.241 1.00 22.28  ? 279  ILE B N     1 
ATOM   5530  C CA    . ILE B 1 279 ? -22.617  -49.621  -19.562 1.00 23.67  ? 279  ILE B CA    1 
ATOM   5531  C C     . ILE B 1 279 ? -22.771  -49.569  -21.084 1.00 21.85  ? 279  ILE B C     1 
ATOM   5532  O O     . ILE B 1 279 ? -21.787  -49.507  -21.826 1.00 23.96  ? 279  ILE B O     1 
ATOM   5533  C CB    . ILE B 1 279 ? -22.517  -48.220  -18.926 1.00 28.10  ? 279  ILE B CB    1 
ATOM   5534  C CG1   . ILE B 1 279 ? -21.497  -47.413  -19.581 1.00 30.26  ? 279  ILE B CG1   1 
ATOM   5535  C CG2   . ILE B 1 279 ? -22.259  -48.263  -17.401 1.00 28.49  ? 279  ILE B CG2   1 
ATOM   5536  C CD1   . ILE B 1 279 ? -21.415  -45.989  -19.048 1.00 37.00  ? 279  ILE B CD1   1 
ATOM   5537  N N     . GLY B 1 280 ? -24.016  -49.573  -21.571 1.00 22.15  ? 280  GLY B N     1 
ATOM   5538  C CA    . GLY B 1 280 ? -24.274  -49.374  -22.995 1.00 21.99  ? 280  GLY B CA    1 
ATOM   5539  C C     . GLY B 1 280 ? -24.792  -47.959  -23.250 1.00 20.82  ? 280  GLY B C     1 
ATOM   5540  O O     . GLY B 1 280 ? -25.772  -47.577  -22.630 1.00 26.05  ? 280  GLY B O     1 
ATOM   5541  N N     . LEU B 1 281 ? -24.134  -47.178  -24.117 1.00 20.68  ? 281  LEU B N     1 
ATOM   5542  C CA    . LEU B 1 281 ? -24.576  -45.808  -24.385 1.00 19.33  ? 281  LEU B CA    1 
ATOM   5543  C C     . LEU B 1 281 ? -25.840  -45.823  -25.261 1.00 19.76  ? 281  LEU B C     1 
ATOM   5544  O O     . LEU B 1 281 ? -26.106  -46.815  -25.953 1.00 17.36  ? 281  LEU B O     1 
ATOM   5545  C CB    . LEU B 1 281 ? -23.467  -44.989  -25.037 1.00 17.09  ? 281  LEU B CB    1 
ATOM   5546  C CG    . LEU B 1 281 ? -22.127  -44.955  -24.299 1.00 18.57  ? 281  LEU B CG    1 
ATOM   5547  C CD1   . LEU B 1 281 ? -21.125  -44.005  -24.986 1.00 16.07  ? 281  LEU B CD1   1 
ATOM   5548  C CD2   . LEU B 1 281 ? -22.280  -44.558  -22.829 1.00 16.62  ? 281  LEU B CD2   1 
ATOM   5549  N N     . THR B 1 282 ? -26.607  -44.726  -25.206 1.00 18.26  ? 282  THR B N     1 
ATOM   5550  C CA    . THR B 1 282 ? -27.698  -44.481  -26.146 1.00 20.73  ? 282  THR B CA    1 
ATOM   5551  C C     . THR B 1 282 ? -27.162  -44.339  -27.578 1.00 21.19  ? 282  THR B C     1 
ATOM   5552  O O     . THR B 1 282 ? -25.959  -44.162  -27.793 1.00 21.09  ? 282  THR B O     1 
ATOM   5553  C CB    . THR B 1 282 ? -28.519  -43.237  -25.756 1.00 19.92  ? 282  THR B CB    1 
ATOM   5554  O OG1   . THR B 1 282 ? -27.682  -42.124  -26.060 1.00 21.43  ? 282  THR B OG1   1 
ATOM   5555  C CG2   . THR B 1 282 ? -28.960  -43.238  -24.293 1.00 13.76  ? 282  THR B CG2   1 
ATOM   5556  N N     . GLY B 1 283 ? -28.079  -44.389  -28.554 1.00 21.41  ? 283  GLY B N     1 
ATOM   5557  C CA    . GLY B 1 283 ? -27.700  -44.246  -29.944 1.00 18.37  ? 283  GLY B CA    1 
ATOM   5558  C C     . GLY B 1 283 ? -26.799  -43.036  -30.178 1.00 19.11  ? 283  GLY B C     1 
ATOM   5559  O O     . GLY B 1 283 ? -25.785  -43.149  -30.879 1.00 20.79  ? 283  GLY B O     1 
ATOM   5560  N N     . THR B 1 284 ? -27.113  -41.908  -29.534 1.00 18.17  ? 284  THR B N     1 
ATOM   5561  C CA    . THR B 1 284 ? -26.373  -40.674  -29.749 1.00 20.33  ? 284  THR B CA    1 
ATOM   5562  C C     . THR B 1 284 ? -25.184  -40.548  -28.787 1.00 24.05  ? 284  THR B C     1 
ATOM   5563  O O     . THR B 1 284 ? -24.512  -39.524  -28.798 1.00 23.53  ? 284  THR B O     1 
ATOM   5564  C CB    . THR B 1 284 ? -27.314  -39.470  -29.634 1.00 23.99  ? 284  THR B CB    1 
ATOM   5565  O OG1   . THR B 1 284 ? -27.866  -39.600  -28.319 1.00 22.77  ? 284  THR B OG1   1 
ATOM   5566  C CG2   . THR B 1 284 ? -28.387  -39.424  -30.724 1.00 17.61  ? 284  THR B CG2   1 
ATOM   5567  N N     . GLY B 1 285 ? -24.910  -41.567  -27.957 1.00 20.77  ? 285  GLY B N     1 
ATOM   5568  C CA    . GLY B 1 285 ? -23.694  -41.558  -27.162 1.00 18.87  ? 285  GLY B CA    1 
ATOM   5569  C C     . GLY B 1 285 ? -23.836  -41.052  -25.721 1.00 21.67  ? 285  GLY B C     1 
ATOM   5570  O O     . GLY B 1 285 ? -22.820  -40.788  -25.080 1.00 25.92  ? 285  GLY B O     1 
ATOM   5571  N N     . ALA B 1 286 ? -25.058  -40.934  -25.180 1.00 19.61  ? 286  ALA B N     1 
ATOM   5572  C CA    . ALA B 1 286 ? -25.221  -40.530  -23.780 1.00 18.85  ? 286  ALA B CA    1 
ATOM   5573  C C     . ALA B 1 286 ? -25.128  -41.740  -22.851 1.00 20.05  ? 286  ALA B C     1 
ATOM   5574  O O     . ALA B 1 286 ? -25.459  -42.865  -23.244 1.00 22.01  ? 286  ALA B O     1 
ATOM   5575  C CB    . ALA B 1 286 ? -26.560  -39.827  -23.574 1.00 15.60  ? 286  ALA B CB    1 
ATOM   5576  N N     . ILE B 1 287 ? -24.691  -41.496  -21.605 1.00 21.71  ? 287  ILE B N     1 
ATOM   5577  C CA    . ILE B 1 287 ? -24.842  -42.474  -20.544 1.00 23.84  ? 287  ILE B CA    1 
ATOM   5578  C C     . ILE B 1 287 ? -26.311  -42.510  -20.150 1.00 25.47  ? 287  ILE B C     1 
ATOM   5579  O O     . ILE B 1 287 ? -26.871  -41.507  -19.746 1.00 28.13  ? 287  ILE B O     1 
ATOM   5580  C CB    . ILE B 1 287 ? -23.960  -42.131  -19.331 1.00 23.24  ? 287  ILE B CB    1 
ATOM   5581  C CG1   . ILE B 1 287 ? -22.517  -42.016  -19.747 1.00 24.19  ? 287  ILE B CG1   1 
ATOM   5582  C CG2   . ILE B 1 287 ? -24.128  -43.196  -18.249 1.00 18.38  ? 287  ILE B CG2   1 
ATOM   5583  C CD1   . ILE B 1 287 ? -21.547  -41.840  -18.593 1.00 29.12  ? 287  ILE B CD1   1 
ATOM   5584  N N     . PRO B 1 288 ? -27.008  -43.655  -20.258 1.00 27.48  ? 288  PRO B N     1 
ATOM   5585  C CA    . PRO B 1 288 ? -28.420  -43.682  -19.877 1.00 26.56  ? 288  PRO B CA    1 
ATOM   5586  C C     . PRO B 1 288 ? -28.609  -43.488  -18.373 1.00 24.51  ? 288  PRO B C     1 
ATOM   5587  O O     . PRO B 1 288 ? -27.722  -43.829  -17.580 1.00 25.09  ? 288  PRO B O     1 
ATOM   5588  C CB    . PRO B 1 288 ? -28.910  -45.065  -20.296 1.00 25.11  ? 288  PRO B CB    1 
ATOM   5589  C CG    . PRO B 1 288 ? -27.674  -45.825  -20.712 1.00 25.19  ? 288  PRO B CG    1 
ATOM   5590  C CD    . PRO B 1 288 ? -26.466  -44.943  -20.709 1.00 24.67  ? 288  PRO B CD    1 
ATOM   5591  N N     . ALA B 1 289 ? -29.779  -42.967  -17.986 1.00 22.85  ? 289  ALA B N     1 
ATOM   5592  C CA    . ALA B 1 289 ? -30.068  -42.648  -16.598 1.00 23.21  ? 289  ALA B CA    1 
ATOM   5593  C C     . ALA B 1 289 ? -29.901  -43.883  -15.699 1.00 23.75  ? 289  ALA B C     1 
ATOM   5594  O O     . ALA B 1 289 ? -29.334  -43.759  -14.605 1.00 22.79  ? 289  ALA B O     1 
ATOM   5595  C CB    . ALA B 1 289 ? -31.433  -41.967  -16.475 1.00 21.55  ? 289  ALA B CB    1 
ATOM   5596  N N     . ALA B 1 290 ? -30.339  -45.071  -16.159 1.00 22.55  ? 290  ALA B N     1 
ATOM   5597  C CA    . ALA B 1 290 ? -30.209  -46.259  -15.315 1.00 24.95  ? 290  ALA B CA    1 
ATOM   5598  C C     . ALA B 1 290 ? -28.749  -46.523  -14.959 1.00 25.22  ? 290  ALA B C     1 
ATOM   5599  O O     . ALA B 1 290 ? -28.432  -46.833  -13.825 1.00 29.19  ? 290  ALA B O     1 
ATOM   5600  C CB    . ALA B 1 290 ? -30.875  -47.486  -15.945 1.00 22.87  ? 290  ALA B CB    1 
ATOM   5601  N N     . ALA B 1 291 ? -27.851  -46.383  -15.943 1.00 25.00  ? 291  ALA B N     1 
ATOM   5602  C CA    . ALA B 1 291 ? -26.449  -46.663  -15.709 1.00 23.10  ? 291  ALA B CA    1 
ATOM   5603  C C     . ALA B 1 291 ? -25.873  -45.648  -14.717 1.00 23.84  ? 291  ALA B C     1 
ATOM   5604  O O     . ALA B 1 291 ? -25.037  -46.015  -13.883 1.00 25.20  ? 291  ALA B O     1 
ATOM   5605  C CB    . ALA B 1 291 ? -25.679  -46.659  -17.009 1.00 22.87  ? 291  ALA B CB    1 
ATOM   5606  N N     . GLN B 1 292 ? -26.308  -44.383  -14.810 1.00 21.25  ? 292  GLN B N     1 
ATOM   5607  C CA    A GLN B 1 292 ? -25.856  -43.353  -13.888 0.50 23.42  ? 292  GLN B CA    1 
ATOM   5608  C CA    B GLN B 1 292 ? -25.871  -43.336  -13.893 0.50 22.63  ? 292  GLN B CA    1 
ATOM   5609  C C     . GLN B 1 292 ? -26.208  -43.743  -12.452 1.00 23.30  ? 292  GLN B C     1 
ATOM   5610  O O     . GLN B 1 292 ? -25.386  -43.573  -11.552 1.00 23.58  ? 292  GLN B O     1 
ATOM   5611  C CB    A GLN B 1 292 ? -26.342  -41.949  -14.238 0.50 25.41  ? 292  GLN B CB    1 
ATOM   5612  C CB    B GLN B 1 292 ? -26.416  -41.937  -14.224 0.50 23.21  ? 292  GLN B CB    1 
ATOM   5613  C CG    A GLN B 1 292 ? -25.448  -41.238  -15.257 0.50 33.99  ? 292  GLN B CG    1 
ATOM   5614  C CG    B GLN B 1 292 ? -25.774  -41.260  -15.436 0.50 28.60  ? 292  GLN B CG    1 
ATOM   5615  C CD    A GLN B 1 292 ? -24.069  -40.788  -14.772 0.50 34.66  ? 292  GLN B CD    1 
ATOM   5616  C CD    B GLN B 1 292 ? -26.437  -39.996  -15.966 0.50 29.37  ? 292  GLN B CD    1 
ATOM   5617  O OE1   A GLN B 1 292 ? -23.665  -40.933  -13.610 0.50 36.78  ? 292  GLN B OE1   1 
ATOM   5618  O OE1   B GLN B 1 292 ? -26.863  -39.138  -15.185 0.50 30.40  ? 292  GLN B OE1   1 
ATOM   5619  N NE2   A GLN B 1 292 ? -23.305  -40.222  -15.692 0.50 30.63  ? 292  GLN B NE2   1 
ATOM   5620  N NE2   B GLN B 1 292 ? -26.513  -39.850  -17.292 0.50 21.23  ? 292  GLN B NE2   1 
ATOM   5621  N N     . THR B 1 293 ? -27.415  -44.305  -12.231 1.00 18.73  ? 293  THR B N     1 
ATOM   5622  C CA    . THR B 1 293 ? -27.822  -44.721  -10.898 1.00 21.92  ? 293  THR B CA    1 
ATOM   5623  C C     . THR B 1 293 ? -26.832  -45.743  -10.341 1.00 21.79  ? 293  THR B C     1 
ATOM   5624  O O     . THR B 1 293 ? -26.356  -45.592  -9.217  1.00 26.57  ? 293  THR B O     1 
ATOM   5625  C CB    . THR B 1 293 ? -29.269  -45.237  -10.903 1.00 21.60  ? 293  THR B CB    1 
ATOM   5626  O OG1   . THR B 1 293 ? -30.063  -44.055  -11.071 1.00 21.59  ? 293  THR B OG1   1 
ATOM   5627  C CG2   . THR B 1 293 ? -29.639  -46.018  -9.650  1.00 16.81  ? 293  THR B CG2   1 
ATOM   5628  N N     . TYR B 1 294 ? -26.518  -46.777  -11.132 1.00 21.06  ? 294  TYR B N     1 
ATOM   5629  C CA    . TYR B 1 294 ? -25.609  -47.836  -10.705 1.00 19.67  ? 294  TYR B CA    1 
ATOM   5630  C C     . TYR B 1 294 ? -24.215  -47.267  -10.440 1.00 23.00  ? 294  TYR B C     1 
ATOM   5631  O O     . TYR B 1 294 ? -23.565  -47.646  -9.459  1.00 24.55  ? 294  TYR B O     1 
ATOM   5632  C CB    . TYR B 1 294 ? -25.586  -48.999  -11.696 1.00 19.03  ? 294  TYR B CB    1 
ATOM   5633  C CG    . TYR B 1 294 ? -26.791  -49.911  -11.511 1.00 22.23  ? 294  TYR B CG    1 
ATOM   5634  C CD1   . TYR B 1 294 ? -28.056  -49.532  -11.965 1.00 19.76  ? 294  TYR B CD1   1 
ATOM   5635  C CD2   . TYR B 1 294 ? -26.663  -51.158  -10.887 1.00 21.89  ? 294  TYR B CD2   1 
ATOM   5636  C CE1   . TYR B 1 294 ? -29.159  -50.353  -11.778 1.00 20.09  ? 294  TYR B CE1   1 
ATOM   5637  C CE2   . TYR B 1 294 ? -27.760  -51.990  -10.697 1.00 20.09  ? 294  TYR B CE2   1 
ATOM   5638  C CZ    . TYR B 1 294 ? -29.011  -51.586  -11.151 1.00 22.80  ? 294  TYR B CZ    1 
ATOM   5639  O OH    . TYR B 1 294 ? -30.107  -52.390  -10.948 1.00 21.59  ? 294  TYR B OH    1 
ATOM   5640  N N     . MET B 1 295 ? -23.777  -46.325  -11.286 1.00 22.24  ? 295  MET B N     1 
ATOM   5641  C CA    . MET B 1 295 ? -22.474  -45.710  -11.075 1.00 24.22  ? 295  MET B CA    1 
ATOM   5642  C C     . MET B 1 295 ? -22.389  -44.905  -9.785  1.00 23.38  ? 295  MET B C     1 
ATOM   5643  O O     . MET B 1 295 ? -21.383  -44.991  -9.088  1.00 23.98  ? 295  MET B O     1 
ATOM   5644  C CB    . MET B 1 295 ? -22.044  -44.913  -12.301 1.00 24.30  ? 295  MET B CB    1 
ATOM   5645  C CG    . MET B 1 295 ? -21.626  -45.891  -13.418 1.00 32.08  ? 295  MET B CG    1 
ATOM   5646  S SD    . MET B 1 295 ? -21.513  -44.907  -14.925 1.00 47.05  ? 295  MET B SD    1 
ATOM   5647  C CE    . MET B 1 295 ? -19.794  -44.542  -14.550 1.00 45.45  ? 295  MET B CE    1 
ATOM   5648  N N     . HIS B 1 296 ? -23.440  -44.146  -9.460  1.00 25.23  ? 296  HIS B N     1 
ATOM   5649  C CA    . HIS B 1 296 ? -23.469  -43.381  -8.218  1.00 26.47  ? 296  HIS B CA    1 
ATOM   5650  C C     . HIS B 1 296 ? -23.370  -44.308  -7.010  1.00 24.80  ? 296  HIS B C     1 
ATOM   5651  O O     . HIS B 1 296 ? -22.575  -44.031  -6.107  1.00 22.90  ? 296  HIS B O     1 
ATOM   5652  C CB    . HIS B 1 296 ? -24.628  -42.375  -8.155  1.00 25.87  ? 296  HIS B CB    1 
ATOM   5653  C CG    . HIS B 1 296 ? -24.389  -41.190  -9.034  1.00 37.57  ? 296  HIS B CG    1 
ATOM   5654  N ND1   . HIS B 1 296 ? -25.272  -40.769  -10.010 1.00 48.10  ? 296  HIS B ND1   1 
ATOM   5655  C CD2   . HIS B 1 296 ? -23.346  -40.364  -9.129  1.00 40.02  ? 296  HIS B CD2   1 
ATOM   5656  C CE1   . HIS B 1 296 ? -24.763  -39.738  -10.669 1.00 43.36  ? 296  HIS B CE1   1 
ATOM   5657  N NE2   . HIS B 1 296 ? -23.592  -39.489  -10.149 1.00 47.14  ? 296  HIS B NE2   1 
ATOM   5658  N N     . LEU B 1 297 ? -24.144  -45.412  -7.020  1.00 22.86  ? 297  LEU B N     1 
ATOM   5659  C CA    . LEU B 1 297 ? -24.118  -46.342  -5.896  1.00 25.11  ? 297  LEU B CA    1 
ATOM   5660  C C     . LEU B 1 297 ? -22.738  -46.987  -5.784  1.00 24.10  ? 297  LEU B C     1 
ATOM   5661  O O     . LEU B 1 297 ? -22.144  -46.998  -4.708  1.00 25.35  ? 297  LEU B O     1 
ATOM   5662  C CB    . LEU B 1 297 ? -25.251  -47.359  -5.918  1.00 20.73  ? 297  LEU B CB    1 
ATOM   5663  C CG    . LEU B 1 297 ? -26.658  -46.748  -5.886  1.00 19.97  ? 297  LEU B CG    1 
ATOM   5664  C CD1   . LEU B 1 297 ? -27.752  -47.728  -6.293  1.00 16.96  ? 297  LEU B CD1   1 
ATOM   5665  C CD2   . LEU B 1 297 ? -26.973  -46.108  -4.511  1.00 18.68  ? 297  LEU B CD2   1 
ATOM   5666  N N     . LEU B 1 298 ? -22.206  -47.477  -6.907  1.00 22.54  ? 298  LEU B N     1 
ATOM   5667  C CA    . LEU B 1 298 ? -20.909  -48.130  -6.852  1.00 21.70  ? 298  LEU B CA    1 
ATOM   5668  C C     . LEU B 1 298 ? -19.841  -47.142  -6.371  1.00 22.72  ? 298  LEU B C     1 
ATOM   5669  O O     . LEU B 1 298 ? -18.951  -47.499  -5.602  1.00 21.99  ? 298  LEU B O     1 
ATOM   5670  C CB    . LEU B 1 298 ? -20.584  -48.664  -8.238  1.00 22.70  ? 298  LEU B CB    1 
ATOM   5671  C CG    . LEU B 1 298 ? -19.215  -49.350  -8.350  1.00 25.37  ? 298  LEU B CG    1 
ATOM   5672  C CD1   . LEU B 1 298 ? -19.118  -50.492  -7.342  1.00 20.88  ? 298  LEU B CD1   1 
ATOM   5673  C CD2   . LEU B 1 298 ? -19.006  -49.874  -9.731  1.00 19.57  ? 298  LEU B CD2   1 
ATOM   5674  N N     . GLY B 1 299 ? -19.958  -45.878  -6.820  1.00 20.39  ? 299  GLY B N     1 
ATOM   5675  C CA    . GLY B 1 299 ? -19.019  -44.827  -6.474  1.00 19.99  ? 299  GLY B CA    1 
ATOM   5676  C C     . GLY B 1 299 ? -18.946  -44.571  -4.974  1.00 23.42  ? 299  GLY B C     1 
ATOM   5677  O O     . GLY B 1 299 ? -17.861  -44.332  -4.443  1.00 24.51  ? 299  GLY B O     1 
ATOM   5678  N N     . ARG B 1 300 ? -20.095  -44.660  -4.289  1.00 21.75  ? 300  ARG B N     1 
ATOM   5679  C CA    . ARG B 1 300 ? -20.076  -44.470  -2.849  1.00 22.51  ? 300  ARG B CA    1 
ATOM   5680  C C     . ARG B 1 300 ? -19.297  -45.624  -2.218  1.00 21.57  ? 300  ARG B C     1 
ATOM   5681  O O     . ARG B 1 300 ? -18.526  -45.391  -1.290  1.00 21.91  ? 300  ARG B O     1 
ATOM   5682  C CB    . ARG B 1 300 ? -21.486  -44.394  -2.248  1.00 23.23  ? 300  ARG B CB    1 
ATOM   5683  C CG    . ARG B 1 300 ? -22.154  -43.075  -2.583  1.00 21.96  ? 300  ARG B CG    1 
ATOM   5684  C CD    . ARG B 1 300 ? -23.606  -43.249  -2.255  1.00 26.89  ? 300  ARG B CD    1 
ATOM   5685  N NE    . ARG B 1 300 ? -24.309  -41.986  -2.484  1.00 28.33  ? 300  ARG B NE    1 
ATOM   5686  C CZ    . ARG B 1 300 ? -24.197  -40.938  -1.646  1.00 33.99  ? 300  ARG B CZ    1 
ATOM   5687  N NH1   . ARG B 1 300 ? -23.552  -41.024  -0.470  1.00 27.22  ? 300  ARG B NH1   1 
ATOM   5688  N NH2   . ARG B 1 300 ? -24.766  -39.802  -2.006  1.00 32.62  ? 300  ARG B NH2   1 
ATOM   5689  N N     . TRP B 1 301 ? -19.479  -46.845  -2.738  1.00 17.12  ? 301  TRP B N     1 
ATOM   5690  C CA    . TRP B 1 301 ? -18.778  -47.977  -2.149  1.00 19.29  ? 301  TRP B CA    1 
ATOM   5691  C C     . TRP B 1 301 ? -17.269  -47.891  -2.418  1.00 20.32  ? 301  TRP B C     1 
ATOM   5692  O O     . TRP B 1 301 ? -16.464  -48.140  -1.525  1.00 23.06  ? 301  TRP B O     1 
ATOM   5693  C CB    . TRP B 1 301 ? -19.356  -49.321  -2.642  1.00 16.47  ? 301  TRP B CB    1 
ATOM   5694  C CG    . TRP B 1 301 ? -18.760  -50.491  -1.902  1.00 16.16  ? 301  TRP B CG    1 
ATOM   5695  C CD1   . TRP B 1 301 ? -19.188  -51.001  -0.713  1.00 15.00  ? 301  TRP B CD1   1 
ATOM   5696  C CD2   . TRP B 1 301 ? -17.620  -51.291  -2.298  1.00 16.26  ? 301  TRP B CD2   1 
ATOM   5697  N NE1   . TRP B 1 301 ? -18.407  -52.062  -0.347  1.00 15.74  ? 301  TRP B NE1   1 
ATOM   5698  C CE2   . TRP B 1 301 ? -17.438  -52.269  -1.299  1.00 16.59  ? 301  TRP B CE2   1 
ATOM   5699  C CE3   . TRP B 1 301 ? -16.752  -51.284  -3.403  1.00 17.88  ? 301  TRP B CE3   1 
ATOM   5700  C CZ2   . TRP B 1 301 ? -16.415  -53.228  -1.356  1.00 18.02  ? 301  TRP B CZ2   1 
ATOM   5701  C CZ3   . TRP B 1 301 ? -15.748  -52.232  -3.472  1.00 19.11  ? 301  TRP B CZ3   1 
ATOM   5702  C CH2   . TRP B 1 301 ? -15.576  -53.195  -2.453  1.00 19.55  ? 301  TRP B CH2   1 
ATOM   5703  N N     . THR B 1 302 ? -16.878  -47.569  -3.663  1.00 20.01  ? 302  THR B N     1 
ATOM   5704  C CA    . THR B 1 302 ? -15.464  -47.638  -3.993  1.00 22.04  ? 302  THR B CA    1 
ATOM   5705  C C     . THR B 1 302 ? -14.722  -46.498  -3.287  1.00 23.55  ? 302  THR B C     1 
ATOM   5706  O O     . THR B 1 302 ? -13.567  -46.667  -2.926  1.00 26.08  ? 302  THR B O     1 
ATOM   5707  C CB    . THR B 1 302 ? -15.199  -47.664  -5.499  1.00 18.88  ? 302  THR B CB    1 
ATOM   5708  O OG1   . THR B 1 302 ? -15.699  -46.404  -5.934  1.00 17.64  ? 302  THR B OG1   1 
ATOM   5709  C CG2   . THR B 1 302 ? -15.869  -48.823  -6.221  1.00 14.97  ? 302  THR B CG2   1 
ATOM   5710  N N     . ALA B 1 303 ? -15.371  -45.348  -3.069  1.00 20.66  ? 303  ALA B N     1 
ATOM   5711  C CA    . ALA B 1 303 ? -14.724  -44.282  -2.300  1.00 22.37  ? 303  ALA B CA    1 
ATOM   5712  C C     . ALA B 1 303 ? -14.397  -44.780  -0.881  1.00 24.47  ? 303  ALA B C     1 
ATOM   5713  O O     . ALA B 1 303 ? -13.295  -44.560  -0.378  1.00 23.43  ? 303  ALA B O     1 
ATOM   5714  C CB    . ALA B 1 303 ? -15.546  -42.985  -2.279  1.00 15.80  ? 303  ALA B CB    1 
ATOM   5715  N N     . MET B 1 304 ? -15.349  -45.484  -0.250  1.00 21.84  ? 304  MET B N     1 
ATOM   5716  C CA    . MET B 1 304 ? -15.123  -46.035  1.077   1.00 20.14  ? 304  MET B CA    1 
ATOM   5717  C C     . MET B 1 304 ? -14.006  -47.083  1.016   1.00 21.75  ? 304  MET B C     1 
ATOM   5718  O O     . MET B 1 304 ? -13.170  -47.123  1.915   1.00 23.35  ? 304  MET B O     1 
ATOM   5719  C CB    . MET B 1 304 ? -16.464  -46.565  1.634   1.00 17.60  ? 304  MET B CB    1 
ATOM   5720  C CG    . MET B 1 304 ? -16.377  -47.363  2.938   1.00 17.88  ? 304  MET B CG    1 
ATOM   5721  S SD    . MET B 1 304 ? -15.731  -49.049  2.777   1.00 22.02  ? 304  MET B SD    1 
ATOM   5722  C CE    . MET B 1 304 ? -17.091  -49.867  1.887   1.00 19.95  ? 304  MET B CE    1 
ATOM   5723  N N     . ALA B 1 305 ? -13.978  -47.915  -0.050  1.00 19.76  ? 305  ALA B N     1 
ATOM   5724  C CA    . ALA B 1 305 ? -13.078  -49.067  -0.130  1.00 19.97  ? 305  ALA B CA    1 
ATOM   5725  C C     . ALA B 1 305 ? -11.687  -48.718  -0.671  1.00 19.81  ? 305  ALA B C     1 
ATOM   5726  O O     . ALA B 1 305 ? -10.846  -49.607  -0.762  1.00 20.27  ? 305  ALA B O     1 
ATOM   5727  C CB    . ALA B 1 305 ? -13.707  -50.172  -0.983  1.00 17.91  ? 305  ALA B CB    1 
ATOM   5728  N N     . ALA B 1 306 ? -11.458  -47.451  -1.044  1.00 21.31  ? 306  ALA B N     1 
ATOM   5729  C CA    . ALA B 1 306 ? -10.214  -46.989  -1.682  1.00 23.39  ? 306  ALA B CA    1 
ATOM   5730  C C     . ALA B 1 306 ? -8.928   -47.504  -1.009  1.00 24.79  ? 306  ALA B C     1 
ATOM   5731  O O     . ALA B 1 306 ? -7.963   -47.831  -1.702  1.00 24.90  ? 306  ALA B O     1 
ATOM   5732  C CB    . ALA B 1 306 ? -10.195  -45.469  -1.827  1.00 20.43  ? 306  ALA B CB    1 
ATOM   5733  N N     . PRO B 1 307 ? -8.797   -47.575  0.340   1.00 24.84  ? 307  PRO B N     1 
ATOM   5734  C CA    . PRO B 1 307 ? -7.542   -48.069  0.924   1.00 20.74  ? 307  PRO B CA    1 
ATOM   5735  C C     . PRO B 1 307 ? -7.184   -49.489  0.508   1.00 22.57  ? 307  PRO B C     1 
ATOM   5736  O O     . PRO B 1 307 ? -6.022   -49.851  0.618   1.00 24.15  ? 307  PRO B O     1 
ATOM   5737  C CB    . PRO B 1 307 ? -7.726   -47.963  2.451   1.00 20.11  ? 307  PRO B CB    1 
ATOM   5738  C CG    . PRO B 1 307 ? -8.831   -46.899  2.580   1.00 20.65  ? 307  PRO B CG    1 
ATOM   5739  C CD    . PRO B 1 307 ? -9.752   -47.085  1.351   1.00 21.72  ? 307  PRO B CD    1 
ATOM   5740  N N     . VAL B 1 308 ? -8.148   -50.304  0.028   1.00 21.44  ? 308  VAL B N     1 
ATOM   5741  C CA    . VAL B 1 308 ? -7.836   -51.697  -0.249  1.00 18.42  ? 308  VAL B CA    1 
ATOM   5742  C C     . VAL B 1 308 ? -8.182   -52.082  -1.694  1.00 21.33  ? 308  VAL B C     1 
ATOM   5743  O O     . VAL B 1 308 ? -7.647   -53.059  -2.215  1.00 19.97  ? 308  VAL B O     1 
ATOM   5744  C CB    . VAL B 1 308 ? -8.532   -52.650  0.748   1.00 18.18  ? 308  VAL B CB    1 
ATOM   5745  C CG1   . VAL B 1 308 ? -10.063  -52.626  0.636   1.00 17.95  ? 308  VAL B CG1   1 
ATOM   5746  C CG2   . VAL B 1 308 ? -8.024   -54.086  0.580   1.00 15.48  ? 308  VAL B CG2   1 
ATOM   5747  N N     . LEU B 1 309 ? -9.081   -51.341  -2.362  1.00 21.56  ? 309  LEU B N     1 
ATOM   5748  C CA    . LEU B 1 309 ? -9.610   -51.799  -3.642  1.00 19.74  ? 309  LEU B CA    1 
ATOM   5749  C C     . LEU B 1 309 ? -8.487   -51.966  -4.671  1.00 21.56  ? 309  LEU B C     1 
ATOM   5750  O O     . LEU B 1 309 ? -8.556   -52.881  -5.496  1.00 21.49  ? 309  LEU B O     1 
ATOM   5751  C CB    . LEU B 1 309 ? -10.656  -50.802  -4.134  1.00 19.70  ? 309  LEU B CB    1 
ATOM   5752  C CG    . LEU B 1 309 ? -11.273  -51.090  -5.509  1.00 22.91  ? 309  LEU B CG    1 
ATOM   5753  C CD1   . LEU B 1 309 ? -12.026  -52.417  -5.506  1.00 26.21  ? 309  LEU B CD1   1 
ATOM   5754  C CD2   . LEU B 1 309 ? -12.201  -49.974  -5.925  1.00 19.12  ? 309  LEU B CD2   1 
ATOM   5755  N N     . TYR B 1 310 ? -7.481   -51.061  -4.665  1.00 20.55  ? 310  TYR B N     1 
ATOM   5756  C CA    . TYR B 1 310 ? -6.418   -51.043  -5.675  1.00 21.34  ? 310  TYR B CA    1 
ATOM   5757  C C     . TYR B 1 310 ? -5.257   -51.977  -5.320  1.00 21.07  ? 310  TYR B C     1 
ATOM   5758  O O     . TYR B 1 310 ? -4.871   -52.821  -6.124  1.00 23.37  ? 310  TYR B O     1 
ATOM   5759  C CB    . TYR B 1 310 ? -5.985   -49.604  -5.975  1.00 19.78  ? 310  TYR B CB    1 
ATOM   5760  C CG    . TYR B 1 310 ? -7.225   -48.787  -6.297  1.00 19.00  ? 310  TYR B CG    1 
ATOM   5761  C CD1   . TYR B 1 310 ? -7.937   -49.024  -7.468  1.00 19.70  ? 310  TYR B CD1   1 
ATOM   5762  C CD2   . TYR B 1 310 ? -7.734   -47.848  -5.389  1.00 18.30  ? 310  TYR B CD2   1 
ATOM   5763  C CE1   . TYR B 1 310 ? -9.121   -48.342  -7.737  1.00 19.89  ? 310  TYR B CE1   1 
ATOM   5764  C CE2   . TYR B 1 310 ? -8.885   -47.128  -5.651  1.00 17.10  ? 310  TYR B CE2   1 
ATOM   5765  C CZ    . TYR B 1 310 ? -9.587   -47.393  -6.828  1.00 21.81  ? 310  TYR B CZ    1 
ATOM   5766  O OH    . TYR B 1 310 ? -10.748  -46.716  -7.106  1.00 23.31  ? 310  TYR B OH    1 
ATOM   5767  N N     . LYS B 1 311 ? -4.728   -51.869  -4.099  1.00 21.19  ? 311  LYS B N     1 
ATOM   5768  C CA    . LYS B 1 311 ? -3.513   -52.585  -3.727  1.00 22.58  ? 311  LYS B CA    1 
ATOM   5769  C C     . LYS B 1 311 ? -3.807   -53.926  -3.053  1.00 25.17  ? 311  LYS B C     1 
ATOM   5770  O O     . LYS B 1 311 ? -2.888   -54.731  -2.919  1.00 26.05  ? 311  LYS B O     1 
ATOM   5771  C CB    . LYS B 1 311 ? -2.728   -51.718  -2.735  1.00 25.72  ? 311  LYS B CB    1 
ATOM   5772  C CG    . LYS B 1 311 ? -2.297   -50.362  -3.283  1.00 28.99  ? 311  LYS B CG    1 
ATOM   5773  C CD    . LYS B 1 311 ? -1.157   -50.602  -4.258  1.00 35.95  ? 311  LYS B CD    1 
ATOM   5774  C CE    . LYS B 1 311 ? -0.576   -49.302  -4.772  1.00 44.08  ? 311  LYS B CE    1 
ATOM   5775  N NZ    . LYS B 1 311 ? 0.525    -49.625  -5.682  1.00 40.87  ? 311  LYS B NZ    1 
ATOM   5776  N N     . GLY B 1 312 ? -5.058   -54.170  -2.602  1.00 22.10  ? 312  GLY B N     1 
ATOM   5777  C CA    . GLY B 1 312 ? -5.375   -55.392  -1.888  1.00 20.29  ? 312  GLY B CA    1 
ATOM   5778  C C     . GLY B 1 312 ? -5.212   -56.636  -2.770  1.00 24.49  ? 312  GLY B C     1 
ATOM   5779  O O     . GLY B 1 312 ? -5.587   -56.618  -3.948  1.00 24.27  ? 312  GLY B O     1 
ATOM   5780  N N     . ARG B 1 313 ? -4.664   -57.715  -2.193  1.00 19.84  ? 313  ARG B N     1 
ATOM   5781  C CA    . ARG B 1 313 ? -4.410   -58.932  -2.935  1.00 20.52  ? 313  ARG B CA    1 
ATOM   5782  C C     . ARG B 1 313 ? -4.890   -60.126  -2.116  1.00 22.83  ? 313  ARG B C     1 
ATOM   5783  O O     . ARG B 1 313 ? -4.921   -60.068  -0.882  1.00 26.28  ? 313  ARG B O     1 
ATOM   5784  C CB    . ARG B 1 313 ? -2.903   -59.122  -3.205  1.00 17.49  ? 313  ARG B CB    1 
ATOM   5785  C CG    . ARG B 1 313 ? -2.332   -58.111  -4.193  1.00 16.21  ? 313  ARG B CG    1 
ATOM   5786  C CD    . ARG B 1 313 ? -2.956   -58.247  -5.594  1.00 16.11  ? 313  ARG B CD    1 
ATOM   5787  N NE    . ARG B 1 313 ? -2.376   -57.289  -6.552  1.00 16.56  ? 313  ARG B NE    1 
ATOM   5788  C CZ    . ARG B 1 313 ? -2.740   -55.996  -6.665  1.00 17.50  ? 313  ARG B CZ    1 
ATOM   5789  N NH1   . ARG B 1 313 ? -3.823   -55.495  -6.032  1.00 17.56  ? 313  ARG B NH1   1 
ATOM   5790  N NH2   . ARG B 1 313 ? -2.055   -55.205  -7.468  1.00 15.45  ? 313  ARG B NH2   1 
ATOM   5791  N N     . PRO B 1 314 ? -5.265   -61.245  -2.780  1.00 20.10  ? 314  PRO B N     1 
ATOM   5792  C CA    . PRO B 1 314 ? -5.664   -62.438  -2.059  1.00 22.37  ? 314  PRO B CA    1 
ATOM   5793  C C     . PRO B 1 314 ? -4.532   -62.936  -1.171  1.00 23.70  ? 314  PRO B C     1 
ATOM   5794  O O     . PRO B 1 314 ? -3.368   -62.712  -1.469  1.00 24.80  ? 314  PRO B O     1 
ATOM   5795  C CB    . PRO B 1 314 ? -5.903   -63.476  -3.161  1.00 20.54  ? 314  PRO B CB    1 
ATOM   5796  C CG    . PRO B 1 314 ? -6.081   -62.670  -4.411  1.00 18.63  ? 314  PRO B CG    1 
ATOM   5797  C CD    . PRO B 1 314 ? -5.302   -61.401  -4.240  1.00 18.90  ? 314  PRO B CD    1 
ATOM   5798  N N     . VAL B 1 315 ? -4.879   -63.650  -0.109  1.00 26.41  ? 315  VAL B N     1 
ATOM   5799  C CA    . VAL B 1 315 ? -3.883   -64.098  0.850   1.00 28.76  ? 315  VAL B CA    1 
ATOM   5800  C C     . VAL B 1 315 ? -4.437   -65.387  1.432   1.00 31.28  ? 315  VAL B C     1 
ATOM   5801  O O     . VAL B 1 315 ? -5.647   -65.547  1.447   1.00 29.43  ? 315  VAL B O     1 
ATOM   5802  C CB    . VAL B 1 315 ? -3.744   -62.933  1.856   1.00 28.80  ? 315  VAL B CB    1 
ATOM   5803  C CG1   . VAL B 1 315 ? -4.980   -62.714  2.728   1.00 22.97  ? 315  VAL B CG1   1 
ATOM   5804  C CG2   . VAL B 1 315 ? -2.449   -62.984  2.637   1.00 31.25  ? 315  VAL B CG2   1 
ATOM   5805  N N     . PRO B 1 316 ? -3.612   -66.383  1.839   1.00 39.48  ? 316  PRO B N     1 
ATOM   5806  C CA    . PRO B 1 316 ? -4.162   -67.653  2.338   1.00 32.30  ? 316  PRO B CA    1 
ATOM   5807  C C     . PRO B 1 316 ? -4.750   -67.527  3.751   1.00 35.57  ? 316  PRO B C     1 
ATOM   5808  O O     . PRO B 1 316 ? -4.181   -68.009  4.732   1.00 35.35  ? 316  PRO B O     1 
ATOM   5809  C CB    . PRO B 1 316 ? -2.964   -68.610  2.202   1.00 32.87  ? 316  PRO B CB    1 
ATOM   5810  C CG    . PRO B 1 316 ? -1.773   -67.675  2.463   1.00 31.15  ? 316  PRO B CG    1 
ATOM   5811  C CD    . PRO B 1 316 ? -2.134   -66.331  1.867   1.00 34.89  ? 316  PRO B CD    1 
ATOM   5812  N N     . VAL B 1 317 ? -5.854   -66.781  3.871   1.00 32.94  ? 317  VAL B N     1 
ATOM   5813  C CA    . VAL B 1 317 ? -6.543   -66.598  5.132   1.00 31.61  ? 317  VAL B CA    1 
ATOM   5814  C C     . VAL B 1 317 ? -7.994   -66.926  4.834   1.00 39.51  ? 317  VAL B C     1 
ATOM   5815  O O     . VAL B 1 317 ? -8.566   -66.323  3.932   1.00 38.73  ? 317  VAL B O     1 
ATOM   5816  C CB    . VAL B 1 317 ? -6.438   -65.172  5.705   1.00 27.35  ? 317  VAL B CB    1 
ATOM   5817  C CG1   . VAL B 1 317 ? -7.256   -65.029  6.987   1.00 25.83  ? 317  VAL B CG1   1 
ATOM   5818  C CG2   . VAL B 1 317 ? -5.000   -64.760  5.953   1.00 24.13  ? 317  VAL B CG2   1 
ATOM   5819  N N     . THR B 1 318 ? -8.560   -67.922  5.526   1.00 33.81  ? 318  THR B N     1 
ATOM   5820  C CA    . THR B 1 318 ? -9.924   -68.307  5.194   1.00 32.98  ? 318  THR B CA    1 
ATOM   5821  C C     . THR B 1 318 ? -10.894  -67.845  6.284   1.00 30.13  ? 318  THR B C     1 
ATOM   5822  O O     . THR B 1 318 ? -10.493  -67.505  7.399   1.00 31.32  ? 318  THR B O     1 
ATOM   5823  C CB    . THR B 1 318 ? -10.004  -69.806  4.911   1.00 33.45  ? 318  THR B CB    1 
ATOM   5824  O OG1   . THR B 1 318 ? -9.652   -70.466  6.123   1.00 36.11  ? 318  THR B OG1   1 
ATOM   5825  C CG2   . THR B 1 318 ? -9.102   -70.239  3.770   1.00 37.24  ? 318  THR B CG2   1 
ATOM   5826  N N     . SER B 1 319 ? -12.184  -67.833  5.945   1.00 26.27  ? 319  SER B N     1 
ATOM   5827  C CA    . SER B 1 319 ? -13.187  -67.429  6.918   1.00 26.29  ? 319  SER B CA    1 
ATOM   5828  C C     . SER B 1 319 ? -13.805  -68.682  7.543   1.00 22.64  ? 319  SER B C     1 
ATOM   5829  O O     . SER B 1 319 ? -13.722  -69.763  6.986   1.00 23.76  ? 319  SER B O     1 
ATOM   5830  C CB    . SER B 1 319 ? -14.202  -66.526  6.286   1.00 22.98  ? 319  SER B CB    1 
ATOM   5831  O OG    . SER B 1 319 ? -15.042  -67.256  5.411   1.00 29.99  ? 319  SER B OG    1 
ATOM   5832  N N     . ALA B 1 320 ? -14.407  -68.539  8.709   1.00 24.46  ? 320  ALA B N     1 
ATOM   5833  C CA    . ALA B 1 320 ? -15.063  -69.647  9.408   1.00 25.76  ? 320  ALA B CA    1 
ATOM   5834  C C     . ALA B 1 320 ? -16.220  -70.236  8.579   1.00 27.32  ? 320  ALA B C     1 
ATOM   5835  O O     . ALA B 1 320 ? -16.799  -69.574  7.712   1.00 26.69  ? 320  ALA B O     1 
ATOM   5836  C CB    . ALA B 1 320 ? -15.600  -69.111  10.729  1.00 21.87  ? 320  ALA B CB    1 
ATOM   5837  N N     . HIS B 1 321 ? -16.601  -71.460  8.936   1.00 28.46  ? 321  HIS B N     1 
ATOM   5838  C CA    . HIS B 1 321 ? -17.732  -72.186  8.393   1.00 29.99  ? 321  HIS B CA    1 
ATOM   5839  C C     . HIS B 1 321 ? -18.980  -71.301  8.327   1.00 32.99  ? 321  HIS B C     1 
ATOM   5840  O O     . HIS B 1 321 ? -19.375  -70.680  9.328   1.00 30.05  ? 321  HIS B O     1 
ATOM   5841  C CB    . HIS B 1 321 ? -17.962  -73.464  9.212   1.00 30.04  ? 321  HIS B CB    1 
ATOM   5842  C CG    . HIS B 1 321 ? -19.164  -74.212  8.773   1.00 33.76  ? 321  HIS B CG    1 
ATOM   5843  N ND1   . HIS B 1 321 ? -19.214  -75.084  7.703   1.00 32.39  ? 321  HIS B ND1   1 
ATOM   5844  C CD2   . HIS B 1 321 ? -20.408  -74.146  9.271   1.00 35.60  ? 321  HIS B CD2   1 
ATOM   5845  C CE1   . HIS B 1 321 ? -20.458  -75.510  7.549   1.00 31.75  ? 321  HIS B CE1   1 
ATOM   5846  N NE2   . HIS B 1 321 ? -21.194  -74.985  8.499   1.00 37.35  ? 321  HIS B NE2   1 
ATOM   5847  N N     . GLY B 1 322 ? -19.589  -71.267  7.126   1.00 30.12  ? 322  GLY B N     1 
ATOM   5848  C CA    . GLY B 1 322 ? -20.913  -70.696  6.957   1.00 32.26  ? 322  GLY B CA    1 
ATOM   5849  C C     . GLY B 1 322 ? -20.937  -69.182  6.722   1.00 36.72  ? 322  GLY B C     1 
ATOM   5850  O O     . GLY B 1 322 ? -22.007  -68.580  6.781   1.00 37.37  ? 322  GLY B O     1 
ATOM   5851  N N     . THR B 1 323 ? -19.778  -68.555  6.468   1.00 29.67  ? 323  THR B N     1 
ATOM   5852  C CA    . THR B 1 323 ? -19.747  -67.136  6.141   1.00 25.37  ? 323  THR B CA    1 
ATOM   5853  C C     . THR B 1 323 ? -19.113  -67.003  4.766   1.00 24.60  ? 323  THR B C     1 
ATOM   5854  O O     . THR B 1 323 ? -18.460  -67.929  4.311   1.00 23.95  ? 323  THR B O     1 
ATOM   5855  C CB    . THR B 1 323 ? -19.005  -66.306  7.192   1.00 24.59  ? 323  THR B CB    1 
ATOM   5856  O OG1   . THR B 1 323 ? -17.599  -66.430  6.957   1.00 25.37  ? 323  THR B OG1   1 
ATOM   5857  C CG2   . THR B 1 323 ? -19.340  -66.706  8.619   1.00 20.89  ? 323  THR B CG2   1 
ATOM   5858  N N     . ARG B 1 324 ? -19.302  -65.848  4.127   1.00 26.67  ? 324  ARG B N     1 
ATOM   5859  C CA    . ARG B 1 324 ? -18.720  -65.567  2.824   1.00 25.09  ? 324  ARG B CA    1 
ATOM   5860  C C     . ARG B 1 324 ? -17.643  -64.489  3.004   1.00 24.95  ? 324  ARG B C     1 
ATOM   5861  O O     . ARG B 1 324 ? -17.223  -63.865  2.040   1.00 26.19  ? 324  ARG B O     1 
ATOM   5862  C CB    . ARG B 1 324 ? -19.807  -65.037  1.876   1.00 25.53  ? 324  ARG B CB    1 
ATOM   5863  C CG    . ARG B 1 324 ? -21.013  -65.949  1.739   1.00 28.57  ? 324  ARG B CG    1 
ATOM   5864  C CD    . ARG B 1 324 ? -22.028  -65.507  0.684   1.00 29.58  ? 324  ARG B CD    1 
ATOM   5865  N NE    . ARG B 1 324 ? -22.780  -64.312  1.074   1.00 32.63  ? 324  ARG B NE    1 
ATOM   5866  C CZ    . ARG B 1 324 ? -23.088  -63.284  0.251   1.00 29.81  ? 324  ARG B CZ    1 
ATOM   5867  N NH1   . ARG B 1 324 ? -22.684  -63.267  -0.995  1.00 25.31  ? 324  ARG B NH1   1 
ATOM   5868  N NH2   . ARG B 1 324 ? -23.850  -62.284  0.664   1.00 25.53  ? 324  ARG B NH2   1 
ATOM   5869  N N     . ASP B 1 325 ? -17.208  -64.242  4.241   1.00 21.27  ? 325  ASP B N     1 
ATOM   5870  C CA    . ASP B 1 325 ? -16.200  -63.226  4.529   1.00 21.37  ? 325  ASP B CA    1 
ATOM   5871  C C     . ASP B 1 325 ? -14.861  -63.604  3.882   1.00 22.47  ? 325  ASP B C     1 
ATOM   5872  O O     . ASP B 1 325 ? -14.594  -64.784  3.658   1.00 21.09  ? 325  ASP B O     1 
ATOM   5873  C CB    . ASP B 1 325 ? -16.118  -63.004  6.029   1.00 21.43  ? 325  ASP B CB    1 
ATOM   5874  C CG    . ASP B 1 325 ? -17.458  -62.703  6.712   1.00 28.62  ? 325  ASP B CG    1 
ATOM   5875  O OD1   . ASP B 1 325 ? -18.427  -62.222  6.020   1.00 25.37  ? 325  ASP B OD1   1 
ATOM   5876  O OD2   . ASP B 1 325 ? -17.553  -62.967  7.931   1.00 24.52  ? 325  ASP B OD2   1 
ATOM   5877  N N     . PHE B 1 326 ? -13.989  -62.620  3.618   1.00 18.82  ? 326  PHE B N     1 
ATOM   5878  C CA    . PHE B 1 326 ? -12.668  -62.930  3.095   1.00 18.57  ? 326  PHE B CA    1 
ATOM   5879  C C     . PHE B 1 326 ? -11.706  -61.811  3.487   1.00 20.59  ? 326  PHE B C     1 
ATOM   5880  O O     . PHE B 1 326 ? -12.126  -60.782  4.022   1.00 20.25  ? 326  PHE B O     1 
ATOM   5881  C CB    . PHE B 1 326 ? -12.710  -63.121  1.575   1.00 18.47  ? 326  PHE B CB    1 
ATOM   5882  C CG    . PHE B 1 326 ? -13.172  -61.897  0.771   1.00 21.07  ? 326  PHE B CG    1 
ATOM   5883  C CD1   . PHE B 1 326 ? -12.248  -60.951  0.326   1.00 19.00  ? 326  PHE B CD1   1 
ATOM   5884  C CD2   . PHE B 1 326 ? -14.522  -61.709  0.449   1.00 18.29  ? 326  PHE B CD2   1 
ATOM   5885  C CE1   . PHE B 1 326 ? -12.652  -59.856  -0.433  1.00 21.97  ? 326  PHE B CE1   1 
ATOM   5886  C CE2   . PHE B 1 326 ? -14.930  -60.604  -0.303  1.00 21.63  ? 326  PHE B CE2   1 
ATOM   5887  C CZ    . PHE B 1 326 ? -14.006  -59.676  -0.738  1.00 20.37  ? 326  PHE B CZ    1 
ATOM   5888  N N     . VAL B 1 327 ? -10.412  -62.001  3.179   1.00 21.09  ? 327  VAL B N     1 
ATOM   5889  C CA    . VAL B 1 327 ? -9.366   -61.079  3.581   1.00 19.09  ? 327  VAL B CA    1 
ATOM   5890  C C     . VAL B 1 327 ? -8.569   -60.619  2.359   1.00 21.49  ? 327  VAL B C     1 
ATOM   5891  O O     . VAL B 1 327 ? -8.300   -61.407  1.453   1.00 22.19  ? 327  VAL B O     1 
ATOM   5892  C CB    . VAL B 1 327 ? -8.454   -61.808  4.585   1.00 19.29  ? 327  VAL B CB    1 
ATOM   5893  C CG1   . VAL B 1 327 ? -7.365   -60.873  5.115   1.00 16.28  ? 327  VAL B CG1   1 
ATOM   5894  C CG2   . VAL B 1 327 ? -9.278   -62.413  5.728   1.00 19.19  ? 327  VAL B CG2   1 
ATOM   5895  N N     . LEU B 1 328 ? -8.179   -59.332  2.350   1.00 19.88  ? 328  LEU B N     1 
ATOM   5896  C CA    . LEU B 1 328 ? -7.267   -58.803  1.357   1.00 21.25  ? 328  LEU B CA    1 
ATOM   5897  C C     . LEU B 1 328 ? -6.036   -58.240  2.076   1.00 23.17  ? 328  LEU B C     1 
ATOM   5898  O O     . LEU B 1 328 ? -6.137   -57.632  3.143   1.00 23.07  ? 328  LEU B O     1 
ATOM   5899  C CB    . LEU B 1 328 ? -7.967   -57.730  0.512   1.00 18.61  ? 328  LEU B CB    1 
ATOM   5900  C CG    . LEU B 1 328 ? -9.082   -58.221  -0.422  1.00 18.16  ? 328  LEU B CG    1 
ATOM   5901  C CD1   . LEU B 1 328 ? -9.881   -57.039  -1.045  1.00 16.16  ? 328  LEU B CD1   1 
ATOM   5902  C CD2   . LEU B 1 328 ? -8.508   -59.183  -1.467  1.00 14.64  ? 328  LEU B CD2   1 
ATOM   5903  N N     . HIS B 1 329 ? -4.873   -58.408  1.443   1.00 24.85  ? 329  HIS B N     1 
ATOM   5904  C CA    . HIS B 1 329 ? -3.592   -58.004  2.003   1.00 26.67  ? 329  HIS B CA    1 
ATOM   5905  C C     . HIS B 1 329 ? -3.006   -56.835  1.201   1.00 25.14  ? 329  HIS B C     1 
ATOM   5906  O O     . HIS B 1 329 ? -2.996   -56.868  -0.022  1.00 27.03  ? 329  HIS B O     1 
ATOM   5907  C CB    . HIS B 1 329 ? -2.688   -59.237  1.994   1.00 28.94  ? 329  HIS B CB    1 
ATOM   5908  C CG    . HIS B 1 329 ? -1.276   -58.949  2.368   1.00 35.78  ? 329  HIS B CG    1 
ATOM   5909  N ND1   . HIS B 1 329 ? -0.878   -58.815  3.682   1.00 32.81  ? 329  HIS B ND1   1 
ATOM   5910  C CD2   . HIS B 1 329 ? -0.183   -58.774  1.604   1.00 31.63  ? 329  HIS B CD2   1 
ATOM   5911  C CE1   . HIS B 1 329 ? 0.419    -58.574  3.708   1.00 34.18  ? 329  HIS B CE1   1 
ATOM   5912  N NE2   . HIS B 1 329 ? 0.853    -58.535  2.461   1.00 35.59  ? 329  HIS B NE2   1 
ATOM   5913  N N     . THR B 1 330 ? -2.419   -55.916  1.921   1.00 23.85  ? 330  THR B N     1 
ATOM   5914  C CA    . THR B 1 330 ? -1.607   -54.836  1.411   1.00 27.68  ? 330  THR B CA    1 
ATOM   5915  C C     . THR B 1 330 ? -0.269   -54.911  2.160   1.00 29.44  ? 330  THR B C     1 
ATOM   5916  O O     . THR B 1 330 ? -0.111   -55.647  3.102   1.00 31.78  ? 330  THR B O     1 
ATOM   5917  C CB    . THR B 1 330 ? -2.231   -53.434  1.408   1.00 26.43  ? 330  THR B CB    1 
ATOM   5918  O OG1   . THR B 1 330 ? -2.358   -52.921  2.718   1.00 26.98  ? 330  THR B OG1   1 
ATOM   5919  C CG2   . THR B 1 330 ? -3.518   -53.439  0.748   1.00 23.39  ? 330  THR B CG2   1 
ATOM   5920  N N     . SER B 1 331 ? 0.731    -54.197  1.702   1.00 31.41  ? 331  SER B N     1 
ATOM   5921  C CA    . SER B 1 331 ? 2.011    -54.266  2.385   1.00 41.24  ? 331  SER B CA    1 
ATOM   5922  C C     . SER B 1 331 ? 1.929    -53.810  3.827   1.00 40.07  ? 331  SER B C     1 
ATOM   5923  O O     . SER B 1 331 ? 2.558    -54.364  4.664   1.00 46.06  ? 331  SER B O     1 
ATOM   5924  C CB    . SER B 1 331 ? 3.121    -53.572  1.620   1.00 38.24  ? 331  SER B CB    1 
ATOM   5925  O OG    . SER B 1 331 ? 2.904    -52.204  1.516   1.00 41.40  ? 331  SER B OG    1 
ATOM   5926  N N     . LYS B 1 332 ? 1.180    -52.778  4.116   1.00 47.84  ? 332  LYS B N     1 
ATOM   5927  C CA    . LYS B 1 332 ? 1.046    -52.365  5.476   1.00 54.54  ? 332  LYS B CA    1 
ATOM   5928  C C     . LYS B 1 332 ? -0.133   -52.902  6.280   1.00 51.16  ? 332  LYS B C     1 
ATOM   5929  O O     . LYS B 1 332 ? -0.102   -52.813  7.471   1.00 44.04  ? 332  LYS B O     1 
ATOM   5930  C CB    . LYS B 1 332 ? 1.087    -50.853  5.545   1.00 63.49  ? 332  LYS B CB    1 
ATOM   5931  C CG    . LYS B 1 332 ? 2.418    -50.308  5.088   1.00 81.28  ? 332  LYS B CG    1 
ATOM   5932  C CD    . LYS B 1 332 ? 2.761    -48.982  5.735   1.00 98.45  ? 332  LYS B CD    1 
ATOM   5933  C CE    . LYS B 1 332 ? 4.261    -48.816  5.932   1.00 97.50  ? 332  LYS B CE    1 
ATOM   5934  N NZ    . LYS B 1 332 ? 5.062    -48.852  4.679   1.00 90.93  ? 332  LYS B NZ    1 
ATOM   5935  N N     . HIS B 1 333 ? -1.184   -53.428  5.653   1.00 41.04  ? 333  HIS B N     1 
ATOM   5936  C CA    . HIS B 1 333 ? -2.386   -53.895  6.372   1.00 34.04  ? 333  HIS B CA    1 
ATOM   5937  C C     . HIS B 1 333 ? -3.166   -55.101  5.843   1.00 32.85  ? 333  HIS B C     1 
ATOM   5938  O O     . HIS B 1 333 ? -3.083   -55.427  4.705   1.00 35.91  ? 333  HIS B O     1 
ATOM   5939  C CB    . HIS B 1 333 ? -3.467   -52.788  6.360   1.00 29.37  ? 333  HIS B CB    1 
ATOM   5940  C CG    . HIS B 1 333 ? -3.091   -51.510  7.033   1.00 33.76  ? 333  HIS B CG    1 
ATOM   5941  N ND1   . HIS B 1 333 ? -3.004   -51.378  8.391   1.00 40.77  ? 333  HIS B ND1   1 
ATOM   5942  C CD2   . HIS B 1 333 ? -2.741   -50.319  6.525   1.00 36.16  ? 333  HIS B CD2   1 
ATOM   5943  C CE1   . HIS B 1 333 ? -2.616   -50.163  8.693   1.00 34.20  ? 333  HIS B CE1   1 
ATOM   5944  N NE2   . HIS B 1 333 ? -2.450   -49.500  7.575   1.00 37.98  ? 333  HIS B NE2   1 
ATOM   5945  N N     . ASP B 1 334 ? -3.897   -55.800  6.701   1.00 30.61  ? 334  ASP B N     1 
ATOM   5946  C CA    . ASP B 1 334 ? -4.900   -56.730  6.208   1.00 29.15  ? 334  ASP B CA    1 
ATOM   5947  C C     . ASP B 1 334 ? -6.278   -56.096  6.344   1.00 26.40  ? 334  ASP B C     1 
ATOM   5948  O O     . ASP B 1 334 ? -6.464   -55.205  7.178   1.00 25.49  ? 334  ASP B O     1 
ATOM   5949  C CB    . ASP B 1 334 ? -4.771   -58.110  6.820   1.00 27.79  ? 334  ASP B CB    1 
ATOM   5950  C CG    . ASP B 1 334 ? -3.499   -58.837  6.409   1.00 32.16  ? 334  ASP B CG    1 
ATOM   5951  O OD1   . ASP B 1 334 ? -3.122   -58.734  5.226   1.00 37.04  ? 334  ASP B OD1   1 
ATOM   5952  O OD2   . ASP B 1 334 ? -2.876   -59.482  7.268   1.00 31.84  ? 334  ASP B OD2   1 
ATOM   5953  N N     . PHE B 1 335 ? -7.213   -56.522  5.494   1.00 21.31  ? 335  PHE B N     1 
ATOM   5954  C CA    . PHE B 1 335 ? -8.567   -55.989  5.515   1.00 19.99  ? 335  PHE B CA    1 
ATOM   5955  C C     . PHE B 1 335 ? -9.543   -57.157  5.515   1.00 21.54  ? 335  PHE B C     1 
ATOM   5956  O O     . PHE B 1 335 ? -9.409   -58.081  4.702   1.00 24.40  ? 335  PHE B O     1 
ATOM   5957  C CB    . PHE B 1 335 ? -8.775   -55.107  4.280   1.00 18.71  ? 335  PHE B CB    1 
ATOM   5958  C CG    . PHE B 1 335 ? -7.913   -53.855  4.231   1.00 17.54  ? 335  PHE B CG    1 
ATOM   5959  C CD1   . PHE B 1 335 ? -6.607   -53.914  3.737   1.00 16.31  ? 335  PHE B CD1   1 
ATOM   5960  C CD2   . PHE B 1 335 ? -8.416   -52.632  4.651   1.00 15.43  ? 335  PHE B CD2   1 
ATOM   5961  C CE1   . PHE B 1 335 ? -5.835   -52.754  3.652   1.00 16.70  ? 335  PHE B CE1   1 
ATOM   5962  C CE2   . PHE B 1 335 ? -7.632   -51.478  4.580   1.00 18.37  ? 335  PHE B CE2   1 
ATOM   5963  C CZ    . PHE B 1 335 ? -6.347   -51.543  4.087   1.00 16.93  ? 335  PHE B CZ    1 
ATOM   5964  N N     . LEU B 1 336 ? -10.472  -57.130  6.474   1.00 19.21  ? 336  LEU B N     1 
ATOM   5965  C CA    . LEU B 1 336 ? -11.557  -58.093  6.568   1.00 20.35  ? 336  LEU B CA    1 
ATOM   5966  C C     . LEU B 1 336 ? -12.721  -57.520  5.762   1.00 22.73  ? 336  LEU B C     1 
ATOM   5967  O O     . LEU B 1 336 ? -13.181  -56.401  6.030   1.00 23.50  ? 336  LEU B O     1 
ATOM   5968  C CB    . LEU B 1 336 ? -11.942  -58.310  8.027   1.00 19.51  ? 336  LEU B CB    1 
ATOM   5969  C CG    . LEU B 1 336 ? -10.771  -58.655  8.968   1.00 20.55  ? 336  LEU B CG    1 
ATOM   5970  C CD1   . LEU B 1 336 ? -11.268  -58.731  10.408  1.00 19.51  ? 336  LEU B CD1   1 
ATOM   5971  C CD2   . LEU B 1 336 ? -10.106  -59.965  8.560   1.00 16.73  ? 336  LEU B CD2   1 
ATOM   5972  N N     . CYS B 1 337 ? -13.151  -58.279  4.745   1.00 19.67  ? 337  CYS B N     1 
ATOM   5973  C CA    . CYS B 1 337 ? -14.305  -57.936  3.934   1.00 21.39  ? 337  CYS B CA    1 
ATOM   5974  C C     . CYS B 1 337 ? -15.465  -58.799  4.423   1.00 21.68  ? 337  CYS B C     1 
ATOM   5975  O O     . CYS B 1 337 ? -15.431  -60.022  4.305   1.00 24.43  ? 337  CYS B O     1 
ATOM   5976  C CB    . CYS B 1 337 ? -13.991  -58.147  2.463   1.00 20.54  ? 337  CYS B CB    1 
ATOM   5977  S SG    . CYS B 1 337 ? -12.617  -57.115  1.873   1.00 29.27  ? 337  CYS B SG    1 
ATOM   5978  N N     . ILE B 1 338 ? -16.465  -58.153  5.018   1.00 22.02  ? 338  ILE B N     1 
ATOM   5979  C CA    . ILE B 1 338 ? -17.464  -58.877  5.781   1.00 20.22  ? 338  ILE B CA    1 
ATOM   5980  C C     . ILE B 1 338 ? -18.834  -58.679  5.143   1.00 19.65  ? 338  ILE B C     1 
ATOM   5981  O O     . ILE B 1 338 ? -19.235  -57.547  4.864   1.00 19.66  ? 338  ILE B O     1 
ATOM   5982  C CB    . ILE B 1 338 ? -17.370  -58.454  7.255   1.00 21.19  ? 338  ILE B CB    1 
ATOM   5983  C CG1   . ILE B 1 338 ? -16.021  -58.995  7.809   1.00 22.50  ? 338  ILE B CG1   1 
ATOM   5984  C CG2   . ILE B 1 338 ? -18.568  -58.998  8.035   1.00 19.36  ? 338  ILE B CG2   1 
ATOM   5985  C CD1   . ILE B 1 338 ? -15.737  -58.617  9.236   1.00 27.75  ? 338  ILE B CD1   1 
ATOM   5986  N N     . LEU B 1 339 ? -19.507  -59.798  4.850   1.00 20.28  ? 339  LEU B N     1 
ATOM   5987  C CA    . LEU B 1 339 ? -20.790  -59.826  4.142   1.00 21.58  ? 339  LEU B CA    1 
ATOM   5988  C C     . LEU B 1 339 ? -21.927  -60.218  5.095   1.00 20.92  ? 339  LEU B C     1 
ATOM   5989  O O     . LEU B 1 339 ? -21.682  -60.711  6.194   1.00 18.33  ? 339  LEU B O     1 
ATOM   5990  C CB    . LEU B 1 339 ? -20.712  -60.757  2.929   1.00 22.33  ? 339  LEU B CB    1 
ATOM   5991  C CG    . LEU B 1 339 ? -19.923  -60.219  1.720   1.00 24.33  ? 339  LEU B CG    1 
ATOM   5992  C CD1   . LEU B 1 339 ? -18.394  -60.242  1.947   1.00 25.14  ? 339  LEU B CD1   1 
ATOM   5993  C CD2   . LEU B 1 339 ? -20.284  -60.917  0.397   1.00 19.11  ? 339  LEU B CD2   1 
ATOM   5994  N N     . ASP B 1 340 ? -23.175  -59.995  4.656   1.00 21.31  ? 340  ASP B N     1 
ATOM   5995  C CA    . ASP B 1 340 ? -24.356  -60.472  5.366   1.00 22.22  ? 340  ASP B CA    1 
ATOM   5996  C C     . ASP B 1 340 ? -24.482  -59.790  6.722   1.00 23.66  ? 340  ASP B C     1 
ATOM   5997  O O     . ASP B 1 340 ? -24.849  -60.449  7.676   1.00 28.09  ? 340  ASP B O     1 
ATOM   5998  C CB    . ASP B 1 340 ? -24.379  -61.992  5.462   1.00 19.29  ? 340  ASP B CB    1 
ATOM   5999  C CG    . ASP B 1 340 ? -24.206  -62.654  4.094   1.00 24.47  ? 340  ASP B CG    1 
ATOM   6000  O OD1   . ASP B 1 340 ? -25.032  -62.375  3.190   1.00 25.38  ? 340  ASP B OD1   1 
ATOM   6001  O OD2   . ASP B 1 340 ? -23.210  -63.403  3.892   1.00 25.64  ? 340  ASP B OD2   1 
ATOM   6002  N N     . LEU B 1 341 ? -24.182  -58.495  6.812   1.00 22.32  ? 341  LEU B N     1 
ATOM   6003  C CA    . LEU B 1 341 ? -24.436  -57.747  8.038   1.00 24.66  ? 341  LEU B CA    1 
ATOM   6004  C C     . LEU B 1 341 ? -25.824  -57.126  7.983   1.00 26.75  ? 341  LEU B C     1 
ATOM   6005  O O     . LEU B 1 341 ? -26.327  -56.828  6.898   1.00 28.06  ? 341  LEU B O     1 
ATOM   6006  C CB    . LEU B 1 341 ? -23.385  -56.660  8.256   1.00 20.17  ? 341  LEU B CB    1 
ATOM   6007  C CG    . LEU B 1 341 ? -21.979  -57.173  8.546   1.00 22.15  ? 341  LEU B CG    1 
ATOM   6008  C CD1   . LEU B 1 341 ? -21.036  -55.987  8.627   1.00 20.69  ? 341  LEU B CD1   1 
ATOM   6009  C CD2   . LEU B 1 341 ? -21.959  -57.980  9.815   1.00 22.59  ? 341  LEU B CD2   1 
ATOM   6010  N N     . GLN B 1 342 ? -26.380  -56.826  9.159   1.00 27.49  ? 342  GLN B N     1 
ATOM   6011  C CA    . GLN B 1 342 ? -27.650  -56.118  9.197   1.00 27.98  ? 342  GLN B CA    1 
ATOM   6012  C C     . GLN B 1 342 ? -27.513  -54.754  9.864   1.00 28.52  ? 342  GLN B C     1 
ATOM   6013  O O     . GLN B 1 342 ? -26.461  -54.431  10.425  1.00 26.98  ? 342  GLN B O     1 
ATOM   6014  C CB    . GLN B 1 342 ? -28.651  -57.061  9.837   1.00 27.17  ? 342  GLN B CB    1 
ATOM   6015  C CG    . GLN B 1 342 ? -28.982  -58.217  8.893   1.00 34.44  ? 342  GLN B CG    1 
ATOM   6016  C CD    . GLN B 1 342 ? -29.967  -59.147  9.549   1.00 42.55  ? 342  GLN B CD    1 
ATOM   6017  O OE1   . GLN B 1 342 ? -29.611  -59.908  10.447  1.00 52.19  ? 342  GLN B OE1   1 
ATOM   6018  N NE2   . GLN B 1 342 ? -31.236  -58.999  9.204   1.00 54.13  ? 342  GLN B NE2   1 
ATOM   6019  N N     . VAL B 1 343 ? -28.591  -53.959  9.786   1.00 26.03  ? 343  VAL B N     1 
ATOM   6020  C CA    . VAL B 1 343 ? -28.648  -52.637  10.368  1.00 27.24  ? 343  VAL B CA    1 
ATOM   6021  C C     . VAL B 1 343 ? -28.967  -52.727  11.859  1.00 30.59  ? 343  VAL B C     1 
ATOM   6022  O O     . VAL B 1 343 ? -29.677  -53.614  12.298  1.00 31.45  ? 343  VAL B O     1 
ATOM   6023  C CB    . VAL B 1 343 ? -29.678  -51.784  9.593   1.00 26.14  ? 343  VAL B CB    1 
ATOM   6024  C CG1   . VAL B 1 343 ? -29.760  -50.358  10.146  1.00 24.32  ? 343  VAL B CG1   1 
ATOM   6025  C CG2   . VAL B 1 343 ? -29.354  -51.770  8.096   1.00 22.31  ? 343  VAL B CG2   1 
ATOM   6026  N N     . VAL B 1 344 ? -28.388  -51.819  12.651  1.00 32.59  ? 344  VAL B N     1 
ATOM   6027  C CA    . VAL B 1 344 ? -28.601  -51.749  14.091  1.00 35.38  ? 344  VAL B CA    1 
ATOM   6028  C C     . VAL B 1 344 ? -29.708  -50.741  14.405  1.00 39.64  ? 344  VAL B C     1 
ATOM   6029  O O     . VAL B 1 344 ? -29.547  -49.567  14.093  1.00 43.21  ? 344  VAL B O     1 
ATOM   6030  C CB    . VAL B 1 344 ? -27.280  -51.336  14.778  1.00 33.80  ? 344  VAL B CB    1 
ATOM   6031  C CG1   . VAL B 1 344 ? -27.477  -51.061  16.269  1.00 29.98  ? 344  VAL B CG1   1 
ATOM   6032  C CG2   . VAL B 1 344 ? -26.196  -52.404  14.588  1.00 31.07  ? 344  VAL B CG2   1 
ATOM   6033  N N     . GLY B 1 345 ? -30.787  -51.189  15.075  1.00 37.89  ? 345  GLY B N     1 
ATOM   6034  C CA    . GLY B 1 345 ? -31.800  -50.329  15.693  1.00 40.57  ? 345  GLY B CA    1 
ATOM   6035  C C     . GLY B 1 345 ? -31.414  -49.809  17.090  1.00 48.20  ? 345  GLY B C     1 
ATOM   6036  O O     . GLY B 1 345 ? -30.265  -49.447  17.353  1.00 58.39  ? 345  GLY B O     1 
ATOM   6037  N N     . LYS B 1 346 ? -32.391  -49.725  18.000  1.00 54.12  ? 346  LYS B N     1 
ATOM   6038  C CA    . LYS B 1 346 ? -32.153  -49.193  19.339  1.00 57.35  ? 346  LYS B CA    1 
ATOM   6039  C C     . LYS B 1 346 ? -33.300  -49.628  20.245  1.00 61.72  ? 346  LYS B C     1 
ATOM   6040  O O     . LYS B 1 346 ? -34.458  -49.477  19.854  1.00 61.77  ? 346  LYS B O     1 
ATOM   6041  C CB    . LYS B 1 346 ? -32.053  -47.665  19.401  1.00 54.31  ? 346  LYS B CB    1 
ATOM   6042  C CG    . LYS B 1 346 ? -31.537  -47.160  20.753  1.00 66.25  ? 346  LYS B CG    1 
ATOM   6043  C CD    . LYS B 1 346 ? -31.350  -45.681  21.036  1.00 74.16  ? 346  LYS B CD    1 
ATOM   6044  C CE    . LYS B 1 346 ? -30.305  -45.495  22.098  1.00 77.33  ? 346  LYS B CE    1 
ATOM   6045  N NZ    . LYS B 1 346 ? -29.631  -44.221  21.844  1.00 87.32  ? 346  LYS B NZ    1 
ATOM   6046  N N     . ASP B 1 347 ? -32.943  -50.176  21.425  1.00 72.06  ? 347  ASP B N     1 
ATOM   6047  C CA    . ASP B 1 347 ? -33.873  -50.608  22.467  1.00 81.12  ? 347  ASP B CA    1 
ATOM   6048  C C     . ASP B 1 347 ? -34.890  -51.601  21.901  1.00 77.80  ? 347  ASP B C     1 
ATOM   6049  O O     . ASP B 1 347 ? -34.511  -52.698  21.507  1.00 85.35  ? 347  ASP B O     1 
ATOM   6050  C CB    . ASP B 1 347 ? -34.486  -49.437  23.234  1.00 82.98  ? 347  ASP B CB    1 
ATOM   6051  C CG    . ASP B 1 347 ? -33.500  -48.463  23.879  1.00 88.65  ? 347  ASP B CG    1 
ATOM   6052  O OD1   . ASP B 1 347 ? -32.526  -48.927  24.518  1.00 87.00  ? 347  ASP B OD1   1 
ATOM   6053  O OD2   . ASP B 1 347 ? -33.712  -47.234  23.762  1.00 82.47  ? 347  ASP B OD2   1 
ATOM   6054  N N     . ASN B 1 348 ? -36.159  -51.188  21.834  1.00 82.94  ? 348  ASN B N     1 
ATOM   6055  C CA    . ASN B 1 348 ? -37.269  -52.035  21.417  1.00 87.56  ? 348  ASN B CA    1 
ATOM   6056  C C     . ASN B 1 348 ? -37.270  -52.256  19.902  1.00 82.58  ? 348  ASN B C     1 
ATOM   6057  O O     . ASN B 1 348 ? -37.875  -53.218  19.410  1.00 79.21  ? 348  ASN B O     1 
ATOM   6058  C CB    . ASN B 1 348 ? -38.625  -51.433  21.777  1.00 94.54  ? 348  ASN B CB    1 
ATOM   6059  C CG    . ASN B 1 348 ? -38.769  -50.995  23.215  1.00 110.74 ? 348  ASN B CG    1 
ATOM   6060  O OD1   . ASN B 1 348 ? -38.308  -51.678  24.140  1.00 119.17 ? 348  ASN B OD1   1 
ATOM   6061  N ND2   . ASN B 1 348 ? -39.327  -49.812  23.399  1.00 103.99 ? 348  ASN B ND2   1 
ATOM   6062  N N     . VAL B 1 349 ? -36.611  -51.340  19.165  1.00 70.20  ? 349  VAL B N     1 
ATOM   6063  C CA    . VAL B 1 349 ? -36.612  -51.339  17.704  1.00 72.16  ? 349  VAL B CA    1 
ATOM   6064  C C     . VAL B 1 349 ? -35.436  -52.179  17.185  1.00 66.35  ? 349  VAL B C     1 
ATOM   6065  O O     . VAL B 1 349 ? -34.273  -51.767  17.246  1.00 60.65  ? 349  VAL B O     1 
ATOM   6066  C CB    . VAL B 1 349 ? -36.623  -49.915  17.109  1.00 64.43  ? 349  VAL B CB    1 
ATOM   6067  C CG1   . VAL B 1 349 ? -36.846  -49.894  15.590  1.00 51.94  ? 349  VAL B CG1   1 
ATOM   6068  C CG2   . VAL B 1 349 ? -37.631  -49.038  17.847  1.00 50.81  ? 349  VAL B CG2   1 
ATOM   6069  N N     . VAL B 1 350 ? -35.778  -53.382  16.705  1.00 48.22  ? 350  VAL B N     1 
ATOM   6070  C CA    . VAL B 1 350 ? -34.816  -54.438  16.423  1.00 52.49  ? 350  VAL B CA    1 
ATOM   6071  C C     . VAL B 1 350 ? -34.762  -54.605  14.904  1.00 50.19  ? 350  VAL B C     1 
ATOM   6072  O O     . VAL B 1 350 ? -35.763  -54.978  14.303  1.00 45.12  ? 350  VAL B O     1 
ATOM   6073  C CB    . VAL B 1 350 ? -35.204  -55.751  17.148  1.00 49.48  ? 350  VAL B CB    1 
ATOM   6074  C CG1   . VAL B 1 350 ? -34.386  -56.940  16.657  1.00 41.49  ? 350  VAL B CG1   1 
ATOM   6075  C CG2   . VAL B 1 350 ? -35.090  -55.595  18.668  1.00 45.42  ? 350  VAL B CG2   1 
ATOM   6076  N N     . LEU B 1 351 ? -33.591  -54.319  14.294  1.00 44.75  ? 351  LEU B N     1 
ATOM   6077  C CA    . LEU B 1 351 ? -33.431  -54.388  12.844  1.00 45.97  ? 351  LEU B CA    1 
ATOM   6078  C C     . LEU B 1 351 ? -32.593  -55.599  12.387  1.00 44.37  ? 351  LEU B C     1 
ATOM   6079  O O     . LEU B 1 351 ? -32.551  -55.914  11.194  1.00 49.97  ? 351  LEU B O     1 
ATOM   6080  C CB    . LEU B 1 351 ? -32.936  -53.059  12.265  1.00 47.66  ? 351  LEU B CB    1 
ATOM   6081  C CG    . LEU B 1 351 ? -33.785  -51.825  12.611  1.00 54.47  ? 351  LEU B CG    1 
ATOM   6082  C CD1   . LEU B 1 351 ? -33.043  -50.577  12.205  1.00 48.50  ? 351  LEU B CD1   1 
ATOM   6083  C CD2   . LEU B 1 351 ? -35.194  -51.856  12.003  1.00 51.55  ? 351  LEU B CD2   1 
ATOM   6084  N N     . GLY B 1 352 ? -31.927  -56.289  13.324  1.00 44.97  ? 352  GLY B N     1 
ATOM   6085  C CA    . GLY B 1 352 ? -31.233  -57.544  13.035  1.00 42.87  ? 352  GLY B CA    1 
ATOM   6086  C C     . GLY B 1 352 ? -29.750  -57.524  13.424  1.00 50.26  ? 352  GLY B C     1 
ATOM   6087  O O     . GLY B 1 352 ? -29.175  -58.579  13.687  1.00 43.00  ? 352  GLY B O     1 
ATOM   6088  N N     . GLY B 1 353 ? -29.129  -56.324  13.482  1.00 49.71  ? 353  GLY B N     1 
ATOM   6089  C CA    . GLY B 1 353 ? -27.683  -56.234  13.594  1.00 41.20  ? 353  GLY B CA    1 
ATOM   6090  C C     . GLY B 1 353 ? -27.166  -56.070  15.021  1.00 48.37  ? 353  GLY B C     1 
ATOM   6091  O O     . GLY B 1 353 ? -25.949  -55.968  15.206  1.00 45.26  ? 353  GLY B O     1 
ATOM   6092  N N     . GLU B 1 354 ? -28.058  -56.087  16.033  1.00 48.88  ? 354  GLU B N     1 
ATOM   6093  C CA    . GLU B 1 354 ? -27.682  -55.601  17.362  1.00 50.48  ? 354  GLU B CA    1 
ATOM   6094  C C     . GLU B 1 354 ? -26.885  -56.594  18.228  1.00 45.38  ? 354  GLU B C     1 
ATOM   6095  O O     . GLU B 1 354 ? -26.077  -56.142  19.048  1.00 48.58  ? 354  GLU B O     1 
ATOM   6096  C CB    . GLU B 1 354 ? -28.645  -54.639  18.076  1.00 49.00  ? 354  GLU B CB    1 
ATOM   6097  C CG    . GLU B 1 354 ? -30.115  -55.008  17.950  1.00 46.71  ? 354  GLU B CG    1 
ATOM   6098  C CD    . GLU B 1 354 ? -30.786  -54.893  16.577  1.00 50.20  ? 354  GLU B CD    1 
ATOM   6099  O OE1   . GLU B 1 354 ? -30.997  -55.972  15.969  1.00 45.20  ? 354  GLU B OE1   1 
ATOM   6100  O OE2   . GLU B 1 354 ? -31.147  -53.778  16.133  1.00 41.31  ? 354  GLU B OE2   1 
ATOM   6101  N N     . GLY B 1 355 ? -27.069  -57.917  18.068  1.00 34.89  ? 355  GLY B N     1 
ATOM   6102  C CA    . GLY B 1 355 ? -26.344  -58.850  18.929  1.00 32.83  ? 355  GLY B CA    1 
ATOM   6103  C C     . GLY B 1 355 ? -24.846  -58.896  18.588  1.00 33.27  ? 355  GLY B C     1 
ATOM   6104  O O     . GLY B 1 355 ? -24.443  -58.522  17.492  1.00 32.86  ? 355  GLY B O     1 
ATOM   6105  N N     . VAL B 1 356 ? -24.008  -59.333  19.532  1.00 25.85  ? 356  VAL B N     1 
ATOM   6106  C CA    . VAL B 1 356 ? -22.625  -59.616  19.219  1.00 22.26  ? 356  VAL B CA    1 
ATOM   6107  C C     . VAL B 1 356 ? -22.564  -60.638  18.078  1.00 25.15  ? 356  VAL B C     1 
ATOM   6108  O O     . VAL B 1 356 ? -23.315  -61.625  18.060  1.00 21.70  ? 356  VAL B O     1 
ATOM   6109  C CB    . VAL B 1 356 ? -21.983  -60.141  20.514  1.00 21.81  ? 356  VAL B CB    1 
ATOM   6110  C CG1   . VAL B 1 356 ? -20.547  -60.574  20.295  1.00 21.54  ? 356  VAL B CG1   1 
ATOM   6111  C CG2   . VAL B 1 356 ? -22.027  -59.072  21.610  1.00 21.56  ? 356  VAL B CG2   1 
ATOM   6112  N N     . ASN B 1 357 ? -21.634  -60.413  17.130  1.00 21.70  ? 357  ASN B N     1 
ATOM   6113  C CA    . ASN B 1 357 ? -21.652  -61.121  15.853  1.00 20.23  ? 357  ASN B CA    1 
ATOM   6114  C C     . ASN B 1 357 ? -20.239  -61.623  15.570  1.00 21.70  ? 357  ASN B C     1 
ATOM   6115  O O     . ASN B 1 357 ? -19.483  -61.013  14.806  1.00 21.78  ? 357  ASN B O     1 
ATOM   6116  C CB    . ASN B 1 357 ? -22.194  -60.199  14.761  1.00 19.81  ? 357  ASN B CB    1 
ATOM   6117  C CG    . ASN B 1 357 ? -22.165  -60.790  13.367  1.00 27.00  ? 357  ASN B CG    1 
ATOM   6118  O OD1   . ASN B 1 357 ? -22.099  -62.017  13.159  1.00 24.71  ? 357  ASN B OD1   1 
ATOM   6119  N ND2   . ASN B 1 357 ? -22.182  -59.914  12.374  1.00 26.70  ? 357  ASN B ND2   1 
ATOM   6120  N N     . PRO B 1 358 ? -19.798  -62.734  16.202  1.00 22.50  ? 358  PRO B N     1 
ATOM   6121  C CA    . PRO B 1 358 ? -18.419  -63.190  16.034  1.00 21.79  ? 358  PRO B CA    1 
ATOM   6122  C C     . PRO B 1 358 ? -18.141  -63.752  14.642  1.00 22.60  ? 358  PRO B C     1 
ATOM   6123  O O     . PRO B 1 358 ? -18.773  -64.720  14.235  1.00 27.93  ? 358  PRO B O     1 
ATOM   6124  C CB    . PRO B 1 358 ? -18.222  -64.223  17.142  1.00 20.32  ? 358  PRO B CB    1 
ATOM   6125  C CG    . PRO B 1 358 ? -19.620  -64.605  17.518  1.00 19.52  ? 358  PRO B CG    1 
ATOM   6126  C CD    . PRO B 1 358 ? -20.598  -63.561  17.113  1.00 21.54  ? 358  PRO B CD    1 
ATOM   6127  N N     . ARG B 1 359 ? -17.205  -63.131  13.915  1.00 19.29  ? 359  ARG B N     1 
ATOM   6128  C CA    . ARG B 1 359 ? -16.769  -63.613  12.619  1.00 19.08  ? 359  ARG B CA    1 
ATOM   6129  C C     . ARG B 1 359 ? -15.299  -63.997  12.752  1.00 20.42  ? 359  ARG B C     1 
ATOM   6130  O O     . ARG B 1 359 ? -14.481  -63.185  13.189  1.00 25.58  ? 359  ARG B O     1 
ATOM   6131  C CB    . ARG B 1 359 ? -16.978  -62.526  11.551  1.00 17.43  ? 359  ARG B CB    1 
ATOM   6132  C CG    . ARG B 1 359 ? -18.418  -62.065  11.374  1.00 18.16  ? 359  ARG B CG    1 
ATOM   6133  C CD    . ARG B 1 359 ? -19.337  -63.233  10.883  1.00 18.31  ? 359  ARG B CD    1 
ATOM   6134  N NE    . ARG B 1 359 ? -20.698  -62.752  10.608  1.00 21.06  ? 359  ARG B NE    1 
ATOM   6135  C CZ    . ARG B 1 359 ? -21.089  -62.189  9.443   1.00 21.66  ? 359  ARG B CZ    1 
ATOM   6136  N NH1   . ARG B 1 359 ? -20.267  -62.145  8.410   1.00 17.36  ? 359  ARG B NH1   1 
ATOM   6137  N NH2   . ARG B 1 359 ? -22.294  -61.644  9.339   1.00 23.66  ? 359  ARG B NH2   1 
ATOM   6138  N N     . SER B 1 360 ? -14.959  -65.207  12.312  1.00 18.80  ? 360  SER B N     1 
ATOM   6139  C CA    . SER B 1 360 ? -13.631  -65.758  12.497  1.00 18.99  ? 360  SER B CA    1 
ATOM   6140  C C     . SER B 1 360 ? -12.919  -65.981  11.171  1.00 20.01  ? 360  SER B C     1 
ATOM   6141  O O     . SER B 1 360 ? -13.558  -66.151  10.131  1.00 21.88  ? 360  SER B O     1 
ATOM   6142  C CB    . SER B 1 360 ? -13.647  -67.031  13.317  1.00 20.45  ? 360  SER B CB    1 
ATOM   6143  O OG    . SER B 1 360 ? -14.142  -66.745  14.619  1.00 22.40  ? 360  SER B OG    1 
ATOM   6144  N N     . PHE B 1 361 ? -11.573  -65.983  11.266  1.00 19.33  ? 361  PHE B N     1 
ATOM   6145  C CA    . PHE B 1 361 ? -10.669  -66.154  10.153  1.00 19.44  ? 361  PHE B CA    1 
ATOM   6146  C C     . PHE B 1 361 ? -9.515   -67.008  10.651  1.00 21.57  ? 361  PHE B C     1 
ATOM   6147  O O     . PHE B 1 361 ? -9.158   -66.931  11.823  1.00 26.87  ? 361  PHE B O     1 
ATOM   6148  C CB    . PHE B 1 361 ? -10.156  -64.766  9.770   1.00 19.52  ? 361  PHE B CB    1 
ATOM   6149  C CG    . PHE B 1 361 ? -11.304  -63.842  9.378   1.00 18.77  ? 361  PHE B CG    1 
ATOM   6150  C CD1   . PHE B 1 361 ? -11.750  -63.796  8.058   1.00 17.65  ? 361  PHE B CD1   1 
ATOM   6151  C CD2   . PHE B 1 361 ? -11.964  -63.072  10.343  1.00 17.28  ? 361  PHE B CD2   1 
ATOM   6152  C CE1   . PHE B 1 361 ? -12.807  -62.962  7.710   1.00 18.55  ? 361  PHE B CE1   1 
ATOM   6153  C CE2   . PHE B 1 361 ? -13.033  -62.263  10.004  1.00 16.90  ? 361  PHE B CE2   1 
ATOM   6154  C CZ    . PHE B 1 361 ? -13.469  -62.215  8.688   1.00 19.30  ? 361  PHE B CZ    1 
ATOM   6155  N N     . VAL B 1 362 ? -8.967   -67.828  9.752   1.00 20.21  ? 362  VAL B N     1 
ATOM   6156  C CA    . VAL B 1 362 ? -7.854   -68.713  10.033  1.00 22.09  ? 362  VAL B CA    1 
ATOM   6157  C C     . VAL B 1 362 ? -6.711   -68.360  9.087   1.00 24.25  ? 362  VAL B C     1 
ATOM   6158  O O     . VAL B 1 362 ? -6.901   -68.338  7.876   1.00 22.58  ? 362  VAL B O     1 
ATOM   6159  C CB    . VAL B 1 362 ? -8.288   -70.160  9.775   1.00 22.50  ? 362  VAL B CB    1 
ATOM   6160  C CG1   . VAL B 1 362 ? -7.095   -71.117  9.967   1.00 19.70  ? 362  VAL B CG1   1 
ATOM   6161  C CG2   . VAL B 1 362 ? -9.457   -70.534  10.691  1.00 19.34  ? 362  VAL B CG2   1 
ATOM   6162  N N     . GLY B 1 363 ? -5.536   -68.078  9.651   1.00 24.95  ? 363  GLY B N     1 
ATOM   6163  C CA    . GLY B 1 363 ? -4.372   -67.789  8.839   1.00 23.60  ? 363  GLY B CA    1 
ATOM   6164  C C     . GLY B 1 363 ? -3.701   -66.469  9.233   1.00 27.60  ? 363  GLY B C     1 
ATOM   6165  O O     . GLY B 1 363 ? -2.701   -66.090  8.632   1.00 26.83  ? 363  GLY B O     1 
ATOM   6166  N N     . ILE B 1 364 ? -4.207   -65.785  10.264  1.00 27.49  ? 364  ILE B N     1 
ATOM   6167  C CA    . ILE B 1 364 ? -3.525   -64.600  10.761  1.00 28.98  ? 364  ILE B CA    1 
ATOM   6168  C C     . ILE B 1 364 ? -2.677   -64.964  11.978  1.00 30.89  ? 364  ILE B C     1 
ATOM   6169  O O     . ILE B 1 364 ? -3.214   -65.352  13.018  1.00 36.41  ? 364  ILE B O     1 
ATOM   6170  C CB    . ILE B 1 364 ? -4.581   -63.528  11.039  1.00 32.01  ? 364  ILE B CB    1 
ATOM   6171  C CG1   . ILE B 1 364 ? -5.057   -62.995  9.684   1.00 36.45  ? 364  ILE B CG1   1 
ATOM   6172  C CG2   . ILE B 1 364 ? -4.017   -62.408  11.909  1.00 31.71  ? 364  ILE B CG2   1 
ATOM   6173  C CD1   . ILE B 1 364 ? -6.216   -62.052  9.772   1.00 34.25  ? 364  ILE B CD1   1 
ATOM   6174  N N     . GLY B 1 365 ? -1.353   -64.847  11.817  1.00 34.98  ? 365  GLY B N     1 
ATOM   6175  C CA    . GLY B 1 365 ? -0.383   -65.324  12.801  1.00 35.74  ? 365  GLY B CA    1 
ATOM   6176  C C     . GLY B 1 365 ? 0.289    -64.204  13.614  1.00 32.97  ? 365  GLY B C     1 
ATOM   6177  O O     . GLY B 1 365 ? 0.994    -64.499  14.562  1.00 42.30  ? 365  GLY B O     1 
ATOM   6178  N N     . GLN B 1 366 ? 0.049    -62.930  13.288  1.00 32.29  ? 366  GLN B N     1 
ATOM   6179  C CA    . GLN B 1 366 ? 0.739    -61.817  13.933  1.00 34.44  ? 366  GLN B CA    1 
ATOM   6180  C C     . GLN B 1 366 ? -0.185   -61.138  14.945  1.00 32.45  ? 366  GLN B C     1 
ATOM   6181  O O     . GLN B 1 366 ? -1.386   -61.003  14.709  1.00 34.00  ? 366  GLN B O     1 
ATOM   6182  C CB    . GLN B 1 366 ? 1.211    -60.805  12.881  1.00 34.40  ? 366  GLN B CB    1 
ATOM   6183  C CG    . GLN B 1 366 ? 2.315    -61.311  11.954  1.00 51.79  ? 366  GLN B CG    1 
ATOM   6184  C CD    . GLN B 1 366 ? 3.452    -62.009  12.696  1.00 71.14  ? 366  GLN B CD    1 
ATOM   6185  O OE1   . GLN B 1 366 ? 4.081    -61.460  13.614  1.00 69.74  ? 366  GLN B OE1   1 
ATOM   6186  N NE2   . GLN B 1 366 ? 3.721    -63.255  12.327  1.00 67.89  ? 366  GLN B NE2   1 
ATOM   6187  N N     . PRO B 1 367 ? 0.330    -60.662  16.100  1.00 33.84  ? 367  PRO B N     1 
ATOM   6188  C CA    . PRO B 1 367 ? -0.530   -59.944  17.052  1.00 29.48  ? 367  PRO B CA    1 
ATOM   6189  C C     . PRO B 1 367 ? -1.076   -58.646  16.478  1.00 30.62  ? 367  PRO B C     1 
ATOM   6190  O O     . PRO B 1 367 ? -0.352   -57.938  15.785  1.00 29.78  ? 367  PRO B O     1 
ATOM   6191  C CB    . PRO B 1 367 ? 0.335    -59.688  18.291  1.00 29.76  ? 367  PRO B CB    1 
ATOM   6192  C CG    . PRO B 1 367 ? 1.747    -60.110  17.867  1.00 29.42  ? 367  PRO B CG    1 
ATOM   6193  C CD    . PRO B 1 367 ? 1.730    -60.832  16.550  1.00 29.11  ? 367  PRO B CD    1 
ATOM   6194  N N     . ILE B 1 368 ? -2.322   -58.305  16.825  1.00 27.47  ? 368  ILE B N     1 
ATOM   6195  C CA    . ILE B 1 368 ? -2.988   -57.173  16.210  1.00 25.12  ? 368  ILE B CA    1 
ATOM   6196  C C     . ILE B 1 368 ? -3.075   -56.067  17.249  1.00 28.51  ? 368  ILE B C     1 
ATOM   6197  O O     . ILE B 1 368 ? -3.361   -56.325  18.410  1.00 29.27  ? 368  ILE B O     1 
ATOM   6198  C CB    . ILE B 1 368 ? -4.385   -57.593  15.678  1.00 22.99  ? 368  ILE B CB    1 
ATOM   6199  C CG1   . ILE B 1 368 ? -4.258   -58.387  14.380  1.00 26.16  ? 368  ILE B CG1   1 
ATOM   6200  C CG2   . ILE B 1 368 ? -5.306   -56.387  15.498  1.00 21.20  ? 368  ILE B CG2   1 
ATOM   6201  C CD1   . ILE B 1 368 ? -5.478   -59.201  13.980  1.00 24.75  ? 368  ILE B CD1   1 
ATOM   6202  N N     . GLN B 1 369 ? -2.990   -54.837  16.814  1.00 31.68  ? 369  GLN B N     1 
ATOM   6203  C CA    . GLN B 1 369 ? -3.163   -53.730  17.693  1.00 29.78  ? 369  GLN B CA    1 
ATOM   6204  C C     . GLN B 1 369 ? -4.568   -53.143  17.629  1.00 32.84  ? 369  GLN B C     1 
ATOM   6205  O O     . GLN B 1 369 ? -5.187   -52.925  18.618  1.00 30.84  ? 369  GLN B O     1 
ATOM   6206  C CB    . GLN B 1 369 ? -2.153   -52.659  17.355  1.00 35.40  ? 369  GLN B CB    1 
ATOM   6207  C CG    . GLN B 1 369 ? -2.165   -51.569  18.381  1.00 49.40  ? 369  GLN B CG    1 
ATOM   6208  C CD    . GLN B 1 369 ? -1.398   -50.354  17.990  1.00 72.90  ? 369  GLN B CD    1 
ATOM   6209  O OE1   . GLN B 1 369 ? -0.212   -50.406  17.714  1.00 80.99  ? 369  GLN B OE1   1 
ATOM   6210  N NE2   . GLN B 1 369 ? -2.067   -49.229  18.002  1.00 85.72  ? 369  GLN B NE2   1 
ATOM   6211  N N     . ARG B 1 370 ? -5.074   -52.916  16.436  1.00 28.76  ? 370  ARG B N     1 
ATOM   6212  C CA    . ARG B 1 370 ? -6.351   -52.306  16.279  1.00 28.43  ? 370  ARG B CA    1 
ATOM   6213  C C     . ARG B 1 370 ? -7.090   -52.753  15.033  1.00 30.25  ? 370  ARG B C     1 
ATOM   6214  O O     . ARG B 1 370 ? -6.497   -53.034  14.037  1.00 26.03  ? 370  ARG B O     1 
ATOM   6215  C CB    . ARG B 1 370 ? -6.085   -50.815  16.171  1.00 32.18  ? 370  ARG B CB    1 
ATOM   6216  C CG    . ARG B 1 370 ? -7.076   -49.912  16.794  1.00 39.85  ? 370  ARG B CG    1 
ATOM   6217  C CD    . ARG B 1 370 ? -6.596   -48.489  16.688  1.00 58.71  ? 370  ARG B CD    1 
ATOM   6218  N NE    . ARG B 1 370 ? -7.166   -47.876  15.510  1.00 78.89  ? 370  ARG B NE    1 
ATOM   6219  C CZ    . ARG B 1 370 ? -8.055   -46.902  15.523  1.00 83.81  ? 370  ARG B CZ    1 
ATOM   6220  N NH1   . ARG B 1 370 ? -8.427   -46.367  16.668  1.00 75.43  ? 370  ARG B NH1   1 
ATOM   6221  N NH2   . ARG B 1 370 ? -8.545   -46.444  14.384  1.00 76.68  ? 370  ARG B NH2   1 
ATOM   6222  N N     . ILE B 1 371 ? -8.404   -52.821  15.112  1.00 24.41  ? 371  ILE B N     1 
ATOM   6223  C CA    . ILE B 1 371 ? -9.249   -53.147  13.983  1.00 23.15  ? 371  ILE B CA    1 
ATOM   6224  C C     . ILE B 1 371 ? -10.356  -52.116  13.905  1.00 21.55  ? 371  ILE B C     1 
ATOM   6225  O O     . ILE B 1 371 ? -10.975  -51.867  14.866  1.00 23.92  ? 371  ILE B O     1 
ATOM   6226  C CB    . ILE B 1 371 ? -9.844   -54.574  14.037  1.00 24.31  ? 371  ILE B CB    1 
ATOM   6227  C CG1   . ILE B 1 371 ? -8.782   -55.616  14.363  1.00 23.97  ? 371  ILE B CG1   1 
ATOM   6228  C CG2   . ILE B 1 371 ? -10.482  -54.914  12.715  1.00 21.36  ? 371  ILE B CG2   1 
ATOM   6229  C CD1   . ILE B 1 371 ? -9.213   -57.039  14.261  1.00 21.58  ? 371  ILE B CD1   1 
ATOM   6230  N N     . HIS B 1 372 ? -10.631  -51.555  12.748  1.00 20.68  ? 372  HIS B N     1 
ATOM   6231  C CA    . HIS B 1 372 ? -11.687  -50.551  12.667  1.00 23.91  ? 372  HIS B CA    1 
ATOM   6232  C C     . HIS B 1 372 ? -12.382  -50.596  11.298  1.00 24.21  ? 372  HIS B C     1 
ATOM   6233  O O     . HIS B 1 372 ? -11.740  -50.861  10.270  1.00 25.65  ? 372  HIS B O     1 
ATOM   6234  C CB    . HIS B 1 372 ? -11.157  -49.149  13.013  1.00 22.38  ? 372  HIS B CB    1 
ATOM   6235  C CG    . HIS B 1 372 ? -10.195  -48.615  12.008  1.00 30.61  ? 372  HIS B CG    1 
ATOM   6236  N ND1   . HIS B 1 372 ? -8.825   -48.859  12.055  1.00 34.45  ? 372  HIS B ND1   1 
ATOM   6237  C CD2   . HIS B 1 372 ? -10.438  -47.829  10.913  1.00 29.81  ? 372  HIS B CD2   1 
ATOM   6238  C CE1   . HIS B 1 372 ? -8.268   -48.255  11.002  1.00 39.71  ? 372  HIS B CE1   1 
ATOM   6239  N NE2   . HIS B 1 372 ? -9.221   -47.617  10.314  1.00 37.09  ? 372  HIS B NE2   1 
ATOM   6240  N N     . TRP B 1 373 ? -13.692  -50.325  11.304  1.00 18.55  ? 373  TRP B N     1 
ATOM   6241  C CA    . TRP B 1 373 ? -14.461  -50.206  10.077  1.00 20.84  ? 373  TRP B CA    1 
ATOM   6242  C C     . TRP B 1 373 ? -14.008  -48.986  9.281   1.00 22.92  ? 373  TRP B C     1 
ATOM   6243  O O     . TRP B 1 373 ? -13.900  -47.893  9.835   1.00 26.22  ? 373  TRP B O     1 
ATOM   6244  C CB    . TRP B 1 373 ? -15.947  -50.040  10.428  1.00 18.80  ? 373  TRP B CB    1 
ATOM   6245  C CG    . TRP B 1 373 ? -16.647  -51.256  10.977  1.00 17.58  ? 373  TRP B CG    1 
ATOM   6246  C CD1   . TRP B 1 373 ? -17.430  -51.262  12.099  1.00 18.41  ? 373  TRP B CD1   1 
ATOM   6247  C CD2   . TRP B 1 373 ? -16.731  -52.587  10.406  1.00 17.22  ? 373  TRP B CD2   1 
ATOM   6248  N NE1   . TRP B 1 373 ? -17.955  -52.517  12.293  1.00 19.49  ? 373  TRP B NE1   1 
ATOM   6249  C CE2   . TRP B 1 373 ? -17.563  -53.349  11.269  1.00 17.22  ? 373  TRP B CE2   1 
ATOM   6250  C CE3   . TRP B 1 373 ? -16.180  -53.215  9.277   1.00 17.51  ? 373  TRP B CE3   1 
ATOM   6251  C CZ2   . TRP B 1 373 ? -17.878  -54.693  11.031  1.00 15.93  ? 373  TRP B CZ2   1 
ATOM   6252  C CZ3   . TRP B 1 373 ? -16.498  -54.545  9.039   1.00 18.37  ? 373  TRP B CZ3   1 
ATOM   6253  C CH2   . TRP B 1 373 ? -17.341  -55.282  9.901   1.00 16.81  ? 373  TRP B CH2   1 
ATOM   6254  N N     . LEU B 1 374 ? -13.809  -49.153  7.967   1.00 24.45  ? 374  LEU B N     1 
ATOM   6255  C CA    . LEU B 1 374 ? -13.454  -48.048  7.083   1.00 22.11  ? 374  LEU B CA    1 
ATOM   6256  C C     . LEU B 1 374 ? -14.566  -47.015  7.012   1.00 23.12  ? 374  LEU B C     1 
ATOM   6257  O O     . LEU B 1 374 ? -14.272  -45.856  6.836   1.00 25.64  ? 374  LEU B O     1 
ATOM   6258  C CB    . LEU B 1 374 ? -13.095  -48.504  5.671   1.00 21.75  ? 374  LEU B CB    1 
ATOM   6259  C CG    . LEU B 1 374 ? -11.818  -49.332  5.540   1.00 20.72  ? 374  LEU B CG    1 
ATOM   6260  C CD1   . LEU B 1 374 ? -11.527  -49.589  4.070   1.00 19.72  ? 374  LEU B CD1   1 
ATOM   6261  C CD2   . LEU B 1 374 ? -10.656  -48.595  6.219   1.00 19.64  ? 374  LEU B CD2   1 
ATOM   6262  N N     . ASP B 1 375 ? -15.842  -47.413  7.084   1.00 26.20  ? 375  ASP B N     1 
ATOM   6263  C CA    . ASP B 1 375 ? -16.905  -46.453  6.801   1.00 23.39  ? 375  ASP B CA    1 
ATOM   6264  C C     . ASP B 1 375 ? -17.074  -45.432  7.933   1.00 26.98  ? 375  ASP B C     1 
ATOM   6265  O O     . ASP B 1 375 ? -17.536  -44.331  7.675   1.00 25.00  ? 375  ASP B O     1 
ATOM   6266  C CB    . ASP B 1 375 ? -18.230  -47.144  6.558   1.00 24.58  ? 375  ASP B CB    1 
ATOM   6267  C CG    . ASP B 1 375 ? -18.623  -48.134  7.661   1.00 27.82  ? 375  ASP B CG    1 
ATOM   6268  O OD1   . ASP B 1 375 ? -18.030  -49.245  7.679   1.00 27.45  ? 375  ASP B OD1   1 
ATOM   6269  O OD2   . ASP B 1 375 ? -19.471  -47.761  8.531   1.00 24.13  ? 375  ASP B OD2   1 
ATOM   6270  N N     . ASN B 1 376 ? -16.772  -45.778  9.199   1.00 23.84  ? 376  ASN B N     1 
ATOM   6271  C CA    . ASN B 1 376 ? -17.078  -44.839  10.272  1.00 22.84  ? 376  ASN B CA    1 
ATOM   6272  C C     . ASN B 1 376 ? -15.993  -44.857  11.351  1.00 24.52  ? 376  ASN B C     1 
ATOM   6273  O O     . ASN B 1 376 ? -16.173  -44.239  12.382  1.00 27.44  ? 376  ASN B O     1 
ATOM   6274  C CB    . ASN B 1 376 ? -18.461  -45.088  10.877  1.00 21.93  ? 376  ASN B CB    1 
ATOM   6275  C CG    . ASN B 1 376 ? -18.519  -46.386  11.666  1.00 26.78  ? 376  ASN B CG    1 
ATOM   6276  O OD1   . ASN B 1 376 ? -17.569  -47.195  11.649  1.00 24.98  ? 376  ASN B OD1   1 
ATOM   6277  N ND2   . ASN B 1 376 ? -19.631  -46.645  12.345  1.00 20.58  ? 376  ASN B ND2   1 
ATOM   6278  N N     . ASP B 1 377 ? -14.907  -45.621  11.160  1.00 24.81  ? 377  ASP B N     1 
ATOM   6279  C CA    . ASP B 1 377 ? -13.809  -45.659  12.121  1.00 29.36  ? 377  ASP B CA    1 
ATOM   6280  C C     . ASP B 1 377 ? -14.158  -46.315  13.459  1.00 28.97  ? 377  ASP B C     1 
ATOM   6281  O O     . ASP B 1 377 ? -13.359  -46.224  14.379  1.00 29.64  ? 377  ASP B O     1 
ATOM   6282  C CB    . ASP B 1 377 ? -13.126  -44.309  12.318  1.00 32.81  ? 377  ASP B CB    1 
ATOM   6283  C CG    . ASP B 1 377 ? -12.382  -43.812  11.081  1.00 44.16  ? 377  ASP B CG    1 
ATOM   6284  O OD1   . ASP B 1 377 ? -11.652  -44.597  10.459  1.00 50.09  ? 377  ASP B OD1   1 
ATOM   6285  O OD2   . ASP B 1 377 ? -12.539  -42.647  10.692  1.00 51.67  ? 377  ASP B OD2   1 
ATOM   6286  N N     . GLU B 1 378 ? -15.303  -46.994  13.584  1.00 26.44  ? 378  GLU B N     1 
ATOM   6287  C CA    . GLU B 1 378 ? -15.573  -47.679  14.841  1.00 27.47  ? 378  GLU B CA    1 
ATOM   6288  C C     . GLU B 1 378 ? -14.520  -48.765  15.074  1.00 26.14  ? 378  GLU B C     1 
ATOM   6289  O O     . GLU B 1 378 ? -14.176  -49.501  14.157  1.00 25.76  ? 378  GLU B O     1 
ATOM   6290  C CB    . GLU B 1 378 ? -17.001  -48.217  14.836  1.00 25.16  ? 378  GLU B CB    1 
ATOM   6291  C CG    . GLU B 1 378 ? -17.356  -48.961  16.116  1.00 27.16  ? 378  GLU B CG    1 
ATOM   6292  C CD    . GLU B 1 378 ? -18.570  -49.875  15.981  1.00 32.48  ? 378  GLU B CD    1 
ATOM   6293  O OE1   . GLU B 1 378 ? -19.122  -50.005  14.875  1.00 35.15  ? 378  GLU B OE1   1 
ATOM   6294  O OE2   . GLU B 1 378 ? -19.003  -50.439  16.993  1.00 35.87  ? 378  GLU B OE2   1 
ATOM   6295  N N     . VAL B 1 379 ? -14.005  -48.845  16.301  1.00 26.33  ? 379  VAL B N     1 
ATOM   6296  C CA    . VAL B 1 379 ? -13.023  -49.844  16.701  1.00 26.30  ? 379  VAL B CA    1 
ATOM   6297  C C     . VAL B 1 379 ? -13.752  -51.133  17.065  1.00 26.86  ? 379  VAL B C     1 
ATOM   6298  O O     . VAL B 1 379 ? -14.742  -51.091  17.790  1.00 27.82  ? 379  VAL B O     1 
ATOM   6299  C CB    . VAL B 1 379 ? -12.251  -49.290  17.922  1.00 27.51  ? 379  VAL B CB    1 
ATOM   6300  C CG1   . VAL B 1 379 ? -11.383  -50.360  18.581  1.00 24.36  ? 379  VAL B CG1   1 
ATOM   6301  C CG2   . VAL B 1 379 ? -11.388  -48.094  17.521  1.00 23.40  ? 379  VAL B CG2   1 
ATOM   6302  N N     . LEU B 1 380 ? -13.253  -52.272  16.573  1.00 25.49  ? 380  LEU B N     1 
ATOM   6303  C CA    . LEU B 1 380 ? -13.893  -53.560  16.798  1.00 27.57  ? 380  LEU B CA    1 
ATOM   6304  C C     . LEU B 1 380 ? -13.192  -54.291  17.946  1.00 26.76  ? 380  LEU B C     1 
ATOM   6305  O O     . LEU B 1 380 ? -11.971  -54.250  18.059  1.00 24.97  ? 380  LEU B O     1 
ATOM   6306  C CB    . LEU B 1 380 ? -13.831  -54.403  15.523  1.00 25.65  ? 380  LEU B CB    1 
ATOM   6307  C CG    . LEU B 1 380 ? -14.416  -53.793  14.245  1.00 26.58  ? 380  LEU B CG    1 
ATOM   6308  C CD1   . LEU B 1 380 ? -14.665  -54.897  13.228  1.00 22.41  ? 380  LEU B CD1   1 
ATOM   6309  C CD2   . LEU B 1 380 ? -15.718  -53.162  14.654  1.00 32.53  ? 380  LEU B CD2   1 
ATOM   6310  N N     . SER B 1 381 ? -13.943  -55.042  18.745  1.00 24.14  ? 381  SER B N     1 
ATOM   6311  C CA    . SER B 1 381 ? -13.241  -55.925  19.667  1.00 24.19  ? 381  SER B CA    1 
ATOM   6312  C C     . SER B 1 381 ? -12.876  -57.237  18.960  1.00 23.74  ? 381  SER B C     1 
ATOM   6313  O O     . SER B 1 381 ? -13.532  -57.629  18.007  1.00 23.18  ? 381  SER B O     1 
ATOM   6314  C CB    . SER B 1 381 ? -14.014  -56.103  20.944  1.00 22.74  ? 381  SER B CB    1 
ATOM   6315  O OG    . SER B 1 381 ? -15.281  -56.629  20.635  1.00 29.41  ? 381  SER B OG    1 
ATOM   6316  N N     . PHE B 1 382 ? -11.808  -57.903  19.409  1.00 23.39  ? 382  PHE B N     1 
ATOM   6317  C CA    . PHE B 1 382 ? -11.319  -59.108  18.769  1.00 22.88  ? 382  PHE B CA    1 
ATOM   6318  C C     . PHE B 1 382 ? -10.546  -59.961  19.787  1.00 26.71  ? 382  PHE B C     1 
ATOM   6319  O O     . PHE B 1 382 ? -10.142  -59.462  20.828  1.00 30.38  ? 382  PHE B O     1 
ATOM   6320  C CB    . PHE B 1 382 ? -10.449  -58.705  17.571  1.00 24.12  ? 382  PHE B CB    1 
ATOM   6321  C CG    . PHE B 1 382 ? -9.127   -58.043  17.964  1.00 25.59  ? 382  PHE B CG    1 
ATOM   6322  C CD1   . PHE B 1 382 ? -7.990   -58.832  18.220  1.00 23.97  ? 382  PHE B CD1   1 
ATOM   6323  C CD2   . PHE B 1 382 ? -9.036   -56.654  18.158  1.00 22.98  ? 382  PHE B CD2   1 
ATOM   6324  C CE1   . PHE B 1 382 ? -6.802   -58.254  18.666  1.00 24.86  ? 382  PHE B CE1   1 
ATOM   6325  C CE2   . PHE B 1 382 ? -7.841   -56.079  18.600  1.00 23.38  ? 382  PHE B CE2   1 
ATOM   6326  C CZ    . PHE B 1 382 ? -6.721   -56.864  18.815  1.00 23.19  ? 382  PHE B CZ    1 
ATOM   6327  N N     . THR B 1 383 ? -10.363  -61.255  19.487  1.00 24.57  ? 383  THR B N     1 
ATOM   6328  C CA    . THR B 1 383 ? -9.526   -62.166  20.240  1.00 27.19  ? 383  THR B CA    1 
ATOM   6329  C C     . THR B 1 383 ? -8.692   -62.936  19.213  1.00 27.77  ? 383  THR B C     1 
ATOM   6330  O O     . THR B 1 383 ? -9.114   -63.105  18.065  1.00 25.71  ? 383  THR B O     1 
ATOM   6331  C CB    . THR B 1 383 ? -10.340  -63.160  21.083  1.00 34.62  ? 383  THR B CB    1 
ATOM   6332  O OG1   . THR B 1 383 ? -11.138  -63.914  20.169  1.00 45.81  ? 383  THR B OG1   1 
ATOM   6333  C CG2   . THR B 1 383 ? -11.281  -62.516  22.088  1.00 31.37  ? 383  THR B CG2   1 
ATOM   6334  N N     . GLN B 1 384 ? -7.509   -63.401  19.631  1.00 26.33  ? 384  GLN B N     1 
ATOM   6335  C CA    . GLN B 1 384 ? -6.641   -64.167  18.761  1.00 25.64  ? 384  GLN B CA    1 
ATOM   6336  C C     . GLN B 1 384 ? -6.192   -65.428  19.467  1.00 26.89  ? 384  GLN B C     1 
ATOM   6337  O O     . GLN B 1 384 ? -6.017   -65.437  20.675  1.00 26.82  ? 384  GLN B O     1 
ATOM   6338  C CB    . GLN B 1 384 ? -5.374   -63.400  18.389  1.00 23.57  ? 384  GLN B CB    1 
ATOM   6339  C CG    . GLN B 1 384 ? -5.665   -62.112  17.635  1.00 24.59  ? 384  GLN B CG    1 
ATOM   6340  C CD    . GLN B 1 384 ? -4.416   -61.453  17.084  1.00 26.90  ? 384  GLN B CD    1 
ATOM   6341  O OE1   . GLN B 1 384 ? -3.909   -60.499  17.689  1.00 32.51  ? 384  GLN B OE1   1 
ATOM   6342  N NE2   . GLN B 1 384 ? -3.939   -61.912  15.932  1.00 21.79  ? 384  GLN B NE2   1 
ATOM   6343  N N     . ASP B 1 385 ? -6.000   -66.495  18.691  1.00 31.77  ? 385  ASP B N     1 
ATOM   6344  C CA    . ASP B 1 385 ? -5.166   -67.618  19.085  1.00 32.52  ? 385  ASP B CA    1 
ATOM   6345  C C     . ASP B 1 385 ? -4.012   -67.680  18.088  1.00 33.58  ? 385  ASP B C     1 
ATOM   6346  O O     . ASP B 1 385 ? -4.195   -68.160  16.961  1.00 28.09  ? 385  ASP B O     1 
ATOM   6347  C CB    . ASP B 1 385 ? -5.964   -68.913  19.135  1.00 35.14  ? 385  ASP B CB    1 
ATOM   6348  C CG    . ASP B 1 385 ? -5.155   -70.180  19.391  1.00 41.29  ? 385  ASP B CG    1 
ATOM   6349  O OD1   . ASP B 1 385 ? -3.923   -70.130  19.235  1.00 40.78  ? 385  ASP B OD1   1 
ATOM   6350  O OD2   . ASP B 1 385 ? -5.770   -71.226  19.736  1.00 52.86  ? 385  ASP B OD2   1 
ATOM   6351  N N     . LEU B 1 386 ? -2.842   -67.185  18.510  1.00 31.01  ? 386  LEU B N     1 
ATOM   6352  C CA    . LEU B 1 386 ? -1.703   -67.055  17.625  1.00 32.40  ? 386  LEU B CA    1 
ATOM   6353  C C     . LEU B 1 386 ? -1.171   -68.421  17.197  1.00 34.14  ? 386  LEU B C     1 
ATOM   6354  O O     . LEU B 1 386 ? -0.729   -68.539  16.056  1.00 34.23  ? 386  LEU B O     1 
ATOM   6355  C CB    . LEU B 1 386 ? -0.624   -66.168  18.237  1.00 32.62  ? 386  LEU B CB    1 
ATOM   6356  C CG    . LEU B 1 386 ? -1.066   -64.730  18.515  1.00 35.12  ? 386  LEU B CG    1 
ATOM   6357  C CD1   . LEU B 1 386 ? 0.043    -64.035  19.336  1.00 34.16  ? 386  LEU B CD1   1 
ATOM   6358  C CD2   . LEU B 1 386 ? -1.371   -63.979  17.191  1.00 33.72  ? 386  LEU B CD2   1 
ATOM   6359  N N     . ASP B 1 387 ? -1.259   -69.451  18.057  1.00 30.07  ? 387  ASP B N     1 
ATOM   6360  C CA    . ASP B 1 387 ? -0.745   -70.751  17.639  1.00 36.10  ? 387  ASP B CA    1 
ATOM   6361  C C     . ASP B 1 387 ? -1.548   -71.340  16.485  1.00 38.48  ? 387  ASP B C     1 
ATOM   6362  O O     . ASP B 1 387 ? -0.977   -71.931  15.578  1.00 34.69  ? 387  ASP B O     1 
ATOM   6363  C CB    . ASP B 1 387 ? -0.617   -71.744  18.786  1.00 43.30  ? 387  ASP B CB    1 
ATOM   6364  C CG    . ASP B 1 387 ? 0.303    -71.246  19.886  1.00 59.17  ? 387  ASP B CG    1 
ATOM   6365  O OD1   . ASP B 1 387 ? 1.462    -70.914  19.549  1.00 59.65  ? 387  ASP B OD1   1 
ATOM   6366  O OD2   . ASP B 1 387 ? -0.160   -71.165  21.048  1.00 67.42  ? 387  ASP B OD2   1 
ATOM   6367  N N     . LYS B 1 388 ? -2.877   -71.199  16.538  1.00 36.55  ? 388  LYS B N     1 
ATOM   6368  C CA    . LYS B 1 388 ? -3.725   -71.812  15.532  1.00 31.53  ? 388  LYS B CA    1 
ATOM   6369  C C     . LYS B 1 388 ? -4.043   -70.804  14.433  1.00 28.21  ? 388  LYS B C     1 
ATOM   6370  O O     . LYS B 1 388 ? -4.637   -71.164  13.425  1.00 27.45  ? 388  LYS B O     1 
ATOM   6371  C CB    . LYS B 1 388 ? -4.914   -72.471  16.235  1.00 35.26  ? 388  LYS B CB    1 
ATOM   6372  C CG    . LYS B 1 388 ? -4.494   -73.840  16.752  1.00 32.28  ? 388  LYS B CG    1 
ATOM   6373  C CD    . LYS B 1 388 ? -5.658   -74.612  17.332  1.00 25.60  ? 388  LYS B CD    1 
ATOM   6374  C CE    . LYS B 1 388 ? -5.237   -76.032  17.614  1.00 23.18  ? 388  LYS B CE    1 
ATOM   6375  N NZ    . LYS B 1 388 ? -6.445   -76.702  18.138  1.00 21.68  ? 388  LYS B NZ    1 
ATOM   6376  N N     . LYS B 1 389 ? -3.611   -69.549  14.632  1.00 25.40  ? 389  LYS B N     1 
ATOM   6377  C CA    . LYS B 1 389 ? -3.752   -68.494  13.643  1.00 27.70  ? 389  LYS B CA    1 
ATOM   6378  C C     . LYS B 1 389 ? -5.234   -68.150  13.462  1.00 27.64  ? 389  LYS B C     1 
ATOM   6379  O O     . LYS B 1 389 ? -5.695   -67.913  12.341  1.00 27.69  ? 389  LYS B O     1 
ATOM   6380  C CB    . LYS B 1 389 ? -3.019   -68.802  12.331  1.00 30.42  ? 389  LYS B CB    1 
ATOM   6381  C CG    . LYS B 1 389 ? -1.536   -69.131  12.474  1.00 34.68  ? 389  LYS B CG    1 
ATOM   6382  C CD    . LYS B 1 389 ? -0.968   -69.419  11.097  1.00 47.64  ? 389  LYS B CD    1 
ATOM   6383  C CE    . LYS B 1 389 ? 0.445    -69.904  11.078  1.00 44.45  ? 389  LYS B CE    1 
ATOM   6384  N NZ    . LYS B 1 389 ? 1.181    -68.669  10.859  1.00 62.48  ? 389  LYS B NZ    1 
ATOM   6385  N N     . VAL B 1 390 ? -5.954   -68.058  14.594  1.00 24.16  ? 390  VAL B N     1 
ATOM   6386  C CA    . VAL B 1 390 ? -7.364   -67.715  14.587  1.00 21.46  ? 390  VAL B CA    1 
ATOM   6387  C C     . VAL B 1 390 ? -7.546   -66.267  15.025  1.00 23.45  ? 390  VAL B C     1 
ATOM   6388  O O     . VAL B 1 390 ? -6.978   -65.851  16.030  1.00 25.54  ? 390  VAL B O     1 
ATOM   6389  C CB    . VAL B 1 390 ? -8.206   -68.666  15.456  1.00 19.90  ? 390  VAL B CB    1 
ATOM   6390  C CG1   . VAL B 1 390 ? -9.679   -68.245  15.490  1.00 18.71  ? 390  VAL B CG1   1 
ATOM   6391  C CG2   . VAL B 1 390 ? -8.077   -70.120  15.000  1.00 16.91  ? 390  VAL B CG2   1 
ATOM   6392  N N     . LEU B 1 391 ? -8.350   -65.520  14.259  1.00 22.53  ? 391  LEU B N     1 
ATOM   6393  C CA    . LEU B 1 391 ? -8.857   -64.212  14.642  1.00 23.17  ? 391  LEU B CA    1 
ATOM   6394  C C     . LEU B 1 391 ? -10.385  -64.248  14.684  1.00 25.67  ? 391  LEU B C     1 
ATOM   6395  O O     . LEU B 1 391 ? -11.023  -64.747  13.746  1.00 26.88  ? 391  LEU B O     1 
ATOM   6396  C CB    . LEU B 1 391 ? -8.366   -63.220  13.579  1.00 22.78  ? 391  LEU B CB    1 
ATOM   6397  C CG    . LEU B 1 391 ? -8.983   -61.815  13.662  1.00 22.59  ? 391  LEU B CG    1 
ATOM   6398  C CD1   . LEU B 1 391 ? -8.577   -61.154  14.982  1.00 22.42  ? 391  LEU B CD1   1 
ATOM   6399  C CD2   . LEU B 1 391 ? -8.596   -60.967  12.466  1.00 19.15  ? 391  LEU B CD2   1 
ATOM   6400  N N     . THR B 1 392 ? -10.974  -63.697  15.758  1.00 23.11  ? 392  THR B N     1 
ATOM   6401  C CA    . THR B 1 392 ? -12.423  -63.562  15.872  1.00 21.98  ? 392  THR B CA    1 
ATOM   6402  C C     . THR B 1 392 ? -12.731  -62.106  16.189  1.00 23.21  ? 392  THR B C     1 
ATOM   6403  O O     . THR B 1 392 ? -12.194  -61.599  17.167  1.00 27.06  ? 392  THR B O     1 
ATOM   6404  C CB    . THR B 1 392 ? -12.973  -64.456  16.981  1.00 22.40  ? 392  THR B CB    1 
ATOM   6405  O OG1   . THR B 1 392 ? -12.588  -65.800  16.701  1.00 22.24  ? 392  THR B OG1   1 
ATOM   6406  C CG2   . THR B 1 392 ? -14.494  -64.393  17.063  1.00 21.02  ? 392  THR B CG2   1 
ATOM   6407  N N     . VAL B 1 393 ? -13.573  -61.449  15.380  1.00 20.37  ? 393  VAL B N     1 
ATOM   6408  C CA    . VAL B 1 393 ? -13.960  -60.065  15.617  1.00 22.83  ? 393  VAL B CA    1 
ATOM   6409  C C     . VAL B 1 393 ? -15.457  -60.048  15.895  1.00 21.96  ? 393  VAL B C     1 
ATOM   6410  O O     . VAL B 1 393 ? -16.201  -60.901  15.391  1.00 22.08  ? 393  VAL B O     1 
ATOM   6411  C CB    . VAL B 1 393 ? -13.656  -59.088  14.457  1.00 22.04  ? 393  VAL B CB    1 
ATOM   6412  C CG1   . VAL B 1 393 ? -12.230  -59.238  14.004  1.00 25.71  ? 393  VAL B CG1   1 
ATOM   6413  C CG2   . VAL B 1 393 ? -14.543  -59.402  13.270  1.00 22.85  ? 393  VAL B CG2   1 
ATOM   6414  N N     . ASP B 1 394 ? -15.886  -59.060  16.688  1.00 19.55  ? 394  ASP B N     1 
ATOM   6415  C CA    . ASP B 1 394 ? -17.306  -58.783  16.800  1.00 20.48  ? 394  ASP B CA    1 
ATOM   6416  C C     . ASP B 1 394 ? -17.660  -57.810  15.677  1.00 21.71  ? 394  ASP B C     1 
ATOM   6417  O O     . ASP B 1 394 ? -17.354  -56.620  15.789  1.00 21.47  ? 394  ASP B O     1 
ATOM   6418  C CB    . ASP B 1 394 ? -17.666  -58.182  18.149  1.00 20.05  ? 394  ASP B CB    1 
ATOM   6419  C CG    . ASP B 1 394 ? -19.117  -57.718  18.255  1.00 28.66  ? 394  ASP B CG    1 
ATOM   6420  O OD1   . ASP B 1 394 ? -19.961  -58.118  17.374  1.00 28.04  ? 394  ASP B OD1   1 
ATOM   6421  O OD2   . ASP B 1 394 ? -19.425  -56.928  19.192  1.00 28.96  ? 394  ASP B OD2   1 
ATOM   6422  N N     . ALA B 1 395 ? -18.266  -58.327  14.595  1.00 19.19  ? 395  ALA B N     1 
ATOM   6423  C CA    . ALA B 1 395 ? -18.562  -57.495  13.438  1.00 21.39  ? 395  ALA B CA    1 
ATOM   6424  C C     . ALA B 1 395 ? -19.887  -56.763  13.669  1.00 21.55  ? 395  ALA B C     1 
ATOM   6425  O O     . ALA B 1 395 ? -20.944  -57.292  13.375  1.00 23.67  ? 395  ALA B O     1 
ATOM   6426  C CB    . ALA B 1 395 ? -18.569  -58.324  12.157  1.00 18.57  ? 395  ALA B CB    1 
ATOM   6427  N N     . THR B 1 396 ? -19.827  -55.555  14.236  1.00 19.07  ? 396  THR B N     1 
ATOM   6428  C CA    . THR B 1 396 ? -21.041  -54.829  14.566  1.00 20.32  ? 396  THR B CA    1 
ATOM   6429  C C     . THR B 1 396 ? -21.806  -54.469  13.288  1.00 21.54  ? 396  THR B C     1 
ATOM   6430  O O     . THR B 1 396 ? -21.221  -54.346  12.202  1.00 19.83  ? 396  THR B O     1 
ATOM   6431  C CB    . THR B 1 396 ? -20.659  -53.595  15.384  1.00 21.30  ? 396  THR B CB    1 
ATOM   6432  O OG1   . THR B 1 396 ? -19.684  -52.871  14.643  1.00 19.29  ? 396  THR B OG1   1 
ATOM   6433  C CG2   . THR B 1 396 ? -20.066  -53.941  16.751  1.00 20.65  ? 396  THR B CG2   1 
ATOM   6434  N N     . GLY B 1 397 ? -23.125  -54.319  13.415  1.00 18.79  ? 397  GLY B N     1 
ATOM   6435  C CA    . GLY B 1 397 ? -23.993  -54.060  12.290  1.00 18.36  ? 397  GLY B CA    1 
ATOM   6436  C C     . GLY B 1 397 ? -23.917  -52.603  11.858  1.00 22.47  ? 397  GLY B C     1 
ATOM   6437  O O     . GLY B 1 397 ? -23.227  -51.796  12.483  1.00 22.58  ? 397  GLY B O     1 
ATOM   6438  N N     . TYR B 1 398 ? -24.611  -52.274  10.757  1.00 22.72  ? 398  TYR B N     1 
ATOM   6439  C CA    . TYR B 1 398 ? -24.530  -50.928  10.208  1.00 21.46  ? 398  TYR B CA    1 
ATOM   6440  C C     . TYR B 1 398 ? -25.220  -49.928  11.125  1.00 21.31  ? 398  TYR B C     1 
ATOM   6441  O O     . TYR B 1 398 ? -26.296  -50.197  11.655  1.00 23.33  ? 398  TYR B O     1 
ATOM   6442  C CB    . TYR B 1 398 ? -25.197  -50.871  8.831   1.00 21.45  ? 398  TYR B CB    1 
ATOM   6443  C CG    . TYR B 1 398 ? -24.554  -51.817  7.834   1.00 22.91  ? 398  TYR B CG    1 
ATOM   6444  C CD1   . TYR B 1 398 ? -23.241  -51.589  7.410   1.00 23.43  ? 398  TYR B CD1   1 
ATOM   6445  C CD2   . TYR B 1 398 ? -25.241  -52.938  7.326   1.00 22.48  ? 398  TYR B CD2   1 
ATOM   6446  C CE1   . TYR B 1 398 ? -22.626  -52.441  6.500   1.00 23.53  ? 398  TYR B CE1   1 
ATOM   6447  C CE2   . TYR B 1 398 ? -24.637  -53.801  6.411   1.00 22.76  ? 398  TYR B CE2   1 
ATOM   6448  C CZ    . TYR B 1 398 ? -23.331  -53.534  6.009   1.00 24.33  ? 398  TYR B CZ    1 
ATOM   6449  O OH    . TYR B 1 398 ? -22.634  -54.317  5.145   1.00 28.97  ? 398  TYR B OH    1 
ATOM   6450  N N     . PRO B 1 399 ? -24.673  -48.707  11.274  1.00 23.21  ? 399  PRO B N     1 
ATOM   6451  C CA    . PRO B 1 399 ? -25.461  -47.617  11.854  1.00 22.75  ? 399  PRO B CA    1 
ATOM   6452  C C     . PRO B 1 399 ? -26.758  -47.427  11.058  1.00 23.97  ? 399  PRO B C     1 
ATOM   6453  O O     . PRO B 1 399 ? -26.762  -47.480  9.821   1.00 22.54  ? 399  PRO B O     1 
ATOM   6454  C CB    . PRO B 1 399 ? -24.596  -46.365  11.680  1.00 20.41  ? 399  PRO B CB    1 
ATOM   6455  C CG    . PRO B 1 399 ? -23.234  -46.863  11.257  1.00 24.70  ? 399  PRO B CG    1 
ATOM   6456  C CD    . PRO B 1 399 ? -23.341  -48.299  10.789  1.00 23.00  ? 399  PRO B CD    1 
ATOM   6457  N N     . TYR B 1 400 ? -27.858  -47.210  11.771  1.00 21.73  ? 400  TYR B N     1 
ATOM   6458  C CA    . TYR B 1 400 ? -29.124  -46.943  11.130  1.00 20.95  ? 400  TYR B CA    1 
ATOM   6459  C C     . TYR B 1 400 ? -28.910  -45.870  10.071  1.00 20.59  ? 400  TYR B C     1 
ATOM   6460  O O     . TYR B 1 400 ? -28.178  -44.902  10.287  1.00 20.97  ? 400  TYR B O     1 
ATOM   6461  C CB    . TYR B 1 400 ? -30.168  -46.547  12.184  1.00 18.84  ? 400  TYR B CB    1 
ATOM   6462  C CG    . TYR B 1 400 ? -31.493  -46.181  11.535  1.00 19.17  ? 400  TYR B CG    1 
ATOM   6463  C CD1   . TYR B 1 400 ? -32.386  -47.157  11.090  1.00 19.09  ? 400  TYR B CD1   1 
ATOM   6464  C CD2   . TYR B 1 400 ? -31.828  -44.850  11.313  1.00 18.96  ? 400  TYR B CD2   1 
ATOM   6465  C CE1   . TYR B 1 400 ? -33.591  -46.820  10.491  1.00 19.37  ? 400  TYR B CE1   1 
ATOM   6466  C CE2   . TYR B 1 400 ? -33.009  -44.501  10.677  1.00 21.55  ? 400  TYR B CE2   1 
ATOM   6467  C CZ    . TYR B 1 400 ? -33.887  -45.487  10.267  1.00 23.35  ? 400  TYR B CZ    1 
ATOM   6468  O OH    . TYR B 1 400 ? -35.045  -45.085  9.659   1.00 26.55  ? 400  TYR B OH    1 
ATOM   6469  N N     . GLY B 1 401 ? -29.545  -46.075  8.913   1.00 18.87  ? 401  GLY B N     1 
ATOM   6470  C CA    . GLY B 1 401 ? -29.454  -45.109  7.847   1.00 17.09  ? 401  GLY B CA    1 
ATOM   6471  C C     . GLY B 1 401 ? -28.360  -45.456  6.846   1.00 18.73  ? 401  GLY B C     1 
ATOM   6472  O O     . GLY B 1 401 ? -28.210  -44.777  5.822   1.00 19.67  ? 401  GLY B O     1 
ATOM   6473  N N     . SER B 1 402 ? -27.609  -46.531  7.100   1.00 18.84  ? 402  SER B N     1 
ATOM   6474  C CA    . SER B 1 402 ? -26.606  -46.879  6.111   1.00 22.54  ? 402  SER B CA    1 
ATOM   6475  C C     . SER B 1 402 ? -26.523  -48.407  5.955   1.00 24.76  ? 402  SER B C     1 
ATOM   6476  O O     . SER B 1 402 ? -27.069  -49.149  6.794   1.00 24.34  ? 402  SER B O     1 
ATOM   6477  C CB    . SER B 1 402 ? -25.310  -46.197  6.438   1.00 22.69  ? 402  SER B CB    1 
ATOM   6478  O OG    . SER B 1 402 ? -24.714  -46.940  7.496   1.00 32.36  ? 402  SER B OG    1 
ATOM   6479  N N     . ASP B 1 403 ? -25.914  -48.867  4.846   1.00 21.06  ? 403  ASP B N     1 
ATOM   6480  C CA    . ASP B 1 403 ? -25.782  -50.286  4.553   1.00 22.65  ? 403  ASP B CA    1 
ATOM   6481  C C     . ASP B 1 403 ? -24.822  -50.429  3.368   1.00 21.92  ? 403  ASP B C     1 
ATOM   6482  O O     . ASP B 1 403 ? -25.180  -50.087  2.234   1.00 20.91  ? 403  ASP B O     1 
ATOM   6483  C CB    . ASP B 1 403 ? -27.136  -50.943  4.292   1.00 23.55  ? 403  ASP B CB    1 
ATOM   6484  C CG    . ASP B 1 403 ? -27.109  -52.460  4.081   1.00 27.94  ? 403  ASP B CG    1 
ATOM   6485  O OD1   . ASP B 1 403 ? -26.030  -52.985  3.680   1.00 26.84  ? 403  ASP B OD1   1 
ATOM   6486  O OD2   . ASP B 1 403 ? -28.148  -53.140  4.361   1.00 24.32  ? 403  ASP B OD2   1 
ATOM   6487  N N     . TRP B 1 404 ? -23.608  -50.938  3.646   1.00 19.62  ? 404  TRP B N     1 
ATOM   6488  C CA    . TRP B 1 404 ? -22.513  -50.902  2.681   1.00 21.15  ? 404  TRP B CA    1 
ATOM   6489  C C     . TRP B 1 404 ? -22.446  -52.195  1.861   1.00 20.77  ? 404  TRP B C     1 
ATOM   6490  O O     . TRP B 1 404 ? -21.648  -52.289  0.927   1.00 22.04  ? 404  TRP B O     1 
ATOM   6491  C CB    . TRP B 1 404 ? -21.178  -50.605  3.384   1.00 18.93  ? 404  TRP B CB    1 
ATOM   6492  C CG    . TRP B 1 404 ? -21.137  -49.212  3.950   1.00 21.29  ? 404  TRP B CG    1 
ATOM   6493  C CD1   . TRP B 1 404 ? -21.477  -48.855  5.224   1.00 20.84  ? 404  TRP B CD1   1 
ATOM   6494  C CD2   . TRP B 1 404 ? -20.797  -47.981  3.264   1.00 19.32  ? 404  TRP B CD2   1 
ATOM   6495  N NE1   . TRP B 1 404 ? -21.376  -47.497  5.372   1.00 19.77  ? 404  TRP B NE1   1 
ATOM   6496  C CE2   . TRP B 1 404 ? -20.946  -46.933  4.199   1.00 20.79  ? 404  TRP B CE2   1 
ATOM   6497  C CE3   . TRP B 1 404 ? -20.372  -47.660  1.966   1.00 21.21  ? 404  TRP B CE3   1 
ATOM   6498  C CZ2   . TRP B 1 404 ? -20.699  -45.592  3.879   1.00 21.58  ? 404  TRP B CZ2   1 
ATOM   6499  C CZ3   . TRP B 1 404 ? -20.107  -46.338  1.644   1.00 21.70  ? 404  TRP B CZ3   1 
ATOM   6500  C CH2   . TRP B 1 404 ? -20.274  -45.315  2.593   1.00 23.51  ? 404  TRP B CH2   1 
ATOM   6501  N N     . VAL B 1 405 ? -23.258  -53.197  2.224   1.00 19.49  ? 405  VAL B N     1 
ATOM   6502  C CA    . VAL B 1 405 ? -23.332  -54.473  1.507   1.00 18.43  ? 405  VAL B CA    1 
ATOM   6503  C C     . VAL B 1 405 ? -22.078  -55.315  1.764   1.00 19.40  ? 405  VAL B C     1 
ATOM   6504  O O     . VAL B 1 405 ? -22.198  -56.449  2.219   1.00 18.13  ? 405  VAL B O     1 
ATOM   6505  C CB    . VAL B 1 405 ? -23.615  -54.366  -0.009  1.00 18.39  ? 405  VAL B CB    1 
ATOM   6506  C CG1   . VAL B 1 405 ? -23.687  -55.739  -0.677  1.00 16.80  ? 405  VAL B CG1   1 
ATOM   6507  C CG2   . VAL B 1 405 ? -24.868  -53.547  -0.293  1.00 16.26  ? 405  VAL B CG2   1 
ATOM   6508  N N     . VAL B 1 406 ? -20.893  -54.814  1.384   1.00 18.93  ? 406  VAL B N     1 
ATOM   6509  C CA    . VAL B 1 406 ? -19.640  -55.427  1.798   1.00 18.44  ? 406  VAL B CA    1 
ATOM   6510  C C     . VAL B 1 406 ? -18.931  -54.422  2.703   1.00 20.65  ? 406  VAL B C     1 
ATOM   6511  O O     . VAL B 1 406 ? -18.554  -53.340  2.243   1.00 24.60  ? 406  VAL B O     1 
ATOM   6512  C CB    . VAL B 1 406 ? -18.734  -55.791  0.602   1.00 17.77  ? 406  VAL B CB    1 
ATOM   6513  C CG1   . VAL B 1 406 ? -17.366  -56.320  1.062   1.00 16.13  ? 406  VAL B CG1   1 
ATOM   6514  C CG2   . VAL B 1 406 ? -19.387  -56.772  -0.359  1.00 14.48  ? 406  VAL B CG2   1 
ATOM   6515  N N     . ARG B 1 407 ? -18.797  -54.748  3.995   1.00 20.62  ? 407  ARG B N     1 
ATOM   6516  C CA    . ARG B 1 407 ? -18.203  -53.815  4.952   1.00 18.82  ? 407  ARG B CA    1 
ATOM   6517  C C     . ARG B 1 407 ? -16.736  -54.205  5.157   1.00 21.31  ? 407  ARG B C     1 
ATOM   6518  O O     . ARG B 1 407 ? -16.405  -55.400  5.144   1.00 21.31  ? 407  ARG B O     1 
ATOM   6519  C CB    . ARG B 1 407 ? -18.965  -53.856  6.273   1.00 18.02  ? 407  ARG B CB    1 
ATOM   6520  C CG    . ARG B 1 407 ? -18.881  -52.536  7.033   1.00 21.13  ? 407  ARG B CG    1 
ATOM   6521  C CD    . ARG B 1 407 ? -19.556  -52.625  8.422   1.00 19.70  ? 407  ARG B CD    1 
ATOM   6522  N NE    . ARG B 1 407 ? -19.545  -51.274  8.974   1.00 17.85  ? 407  ARG B NE    1 
ATOM   6523  C CZ    . ARG B 1 407 ? -20.111  -50.920  10.119  1.00 19.96  ? 407  ARG B CZ    1 
ATOM   6524  N NH1   . ARG B 1 407 ? -20.707  -51.818  10.911  1.00 18.85  ? 407  ARG B NH1   1 
ATOM   6525  N NH2   . ARG B 1 407 ? -20.082  -49.646  10.482  1.00 16.09  ? 407  ARG B NH2   1 
ATOM   6526  N N     . ILE B 1 408 ? -15.848  -53.211  5.312   1.00 19.40  ? 408  ILE B N     1 
ATOM   6527  C CA    . ILE B 1 408 ? -14.429  -53.509  5.323   1.00 19.71  ? 408  ILE B CA    1 
ATOM   6528  C C     . ILE B 1 408 ? -13.794  -52.998  6.613   1.00 22.80  ? 408  ILE B C     1 
ATOM   6529  O O     . ILE B 1 408 ? -13.915  -51.814  6.951   1.00 23.98  ? 408  ILE B O     1 
ATOM   6530  C CB    . ILE B 1 408 ? -13.743  -52.897  4.088   1.00 21.23  ? 408  ILE B CB    1 
ATOM   6531  C CG1   . ILE B 1 408 ? -14.406  -53.354  2.771   1.00 19.54  ? 408  ILE B CG1   1 
ATOM   6532  C CG2   . ILE B 1 408 ? -12.232  -53.191  4.127   1.00 20.20  ? 408  ILE B CG2   1 
ATOM   6533  C CD1   . ILE B 1 408 ? -13.839  -52.706  1.531   1.00 18.76  ? 408  ILE B CD1   1 
ATOM   6534  N N     . ALA B 1 409 ? -13.109  -53.904  7.322   1.00 20.55  ? 409  ALA B N     1 
ATOM   6535  C CA    . ALA B 1 409 ? -12.392  -53.553  8.546   1.00 20.24  ? 409  ALA B CA    1 
ATOM   6536  C C     . ALA B 1 409 ? -10.899  -53.611  8.273   1.00 23.01  ? 409  ALA B C     1 
ATOM   6537  O O     . ALA B 1 409 ? -10.402  -54.613  7.719   1.00 22.20  ? 409  ALA B O     1 
ATOM   6538  C CB    . ALA B 1 409 ? -12.747  -54.534  9.661   1.00 18.34  ? 409  ALA B CB    1 
ATOM   6539  N N     . GLN B 1 410 ? -10.188  -52.532  8.649   1.00 23.03  ? 410  GLN B N     1 
ATOM   6540  C CA    . GLN B 1 410 ? -8.741   -52.500  8.507   1.00 21.83  ? 410  GLN B CA    1 
ATOM   6541  C C     . GLN B 1 410 ? -8.073   -53.010  9.779   1.00 23.35  ? 410  GLN B C     1 
ATOM   6542  O O     . GLN B 1 410 ? -8.419   -52.586  10.892  1.00 23.34  ? 410  GLN B O     1 
ATOM   6543  C CB    . GLN B 1 410 ? -8.297   -51.060  8.319   1.00 27.29  ? 410  GLN B CB    1 
ATOM   6544  C CG    . GLN B 1 410 ? -6.805   -50.925  8.062   1.00 28.40  ? 410  GLN B CG    1 
ATOM   6545  C CD    . GLN B 1 410 ? -6.429   -49.495  7.757   1.00 31.95  ? 410  GLN B CD    1 
ATOM   6546  O OE1   . GLN B 1 410 ? -6.929   -48.892  6.797   1.00 33.61  ? 410  GLN B OE1   1 
ATOM   6547  N NE2   . GLN B 1 410 ? -5.587   -48.935  8.608   1.00 25.11  ? 410  GLN B NE2   1 
ATOM   6548  N N     . ILE B 1 411 ? -7.107   -53.916  9.584   1.00 21.71  ? 411  ILE B N     1 
ATOM   6549  C CA    . ILE B 1 411 ? -6.279   -54.432  10.657  1.00 26.55  ? 411  ILE B CA    1 
ATOM   6550  C C     . ILE B 1 411 ? -4.960   -53.659  10.720  1.00 25.84  ? 411  ILE B C     1 
ATOM   6551  O O     . ILE B 1 411 ? -4.252   -53.573  9.721   1.00 23.32  ? 411  ILE B O     1 
ATOM   6552  C CB    . ILE B 1 411 ? -6.004   -55.931  10.442  1.00 25.39  ? 411  ILE B CB    1 
ATOM   6553  C CG1   . ILE B 1 411 ? -7.290   -56.763  10.517  1.00 24.64  ? 411  ILE B CG1   1 
ATOM   6554  C CG2   . ILE B 1 411 ? -4.944   -56.395  11.442  1.00 24.23  ? 411  ILE B CG2   1 
ATOM   6555  C CD1   . ILE B 1 411 ? -7.118   -58.230  10.154  1.00 23.92  ? 411  ILE B CD1   1 
ATOM   6556  N N     . ASP B 1 412 ? -4.641   -53.115  11.906  1.00 25.29  ? 412  ASP B N     1 
ATOM   6557  C CA    . ASP B 1 412 ? -3.346   -52.495  12.213  1.00 26.29  ? 412  ASP B CA    1 
ATOM   6558  C C     . ASP B 1 412 ? -2.559   -53.446  13.108  1.00 25.23  ? 412  ASP B C     1 
ATOM   6559  O O     . ASP B 1 412 ? -2.995   -53.746  14.222  1.00 29.42  ? 412  ASP B O     1 
ATOM   6560  C CB    . ASP B 1 412 ? -3.541   -51.160  12.916  1.00 24.67  ? 412  ASP B CB    1 
ATOM   6561  C CG    . ASP B 1 412 ? -4.312   -50.127  12.096  1.00 32.90  ? 412  ASP B CG    1 
ATOM   6562  O OD1   . ASP B 1 412 ? -4.410   -50.319  10.855  1.00 33.12  ? 412  ASP B OD1   1 
ATOM   6563  O OD2   . ASP B 1 412 ? -4.831   -49.146  12.677  1.00 38.58  ? 412  ASP B OD2   1 
ATOM   6564  N N     . TYR B 1 413 ? -1.441   -53.955  12.604  1.00 27.72  ? 413  TYR B N     1 
ATOM   6565  C CA    . TYR B 1 413 ? -0.587   -54.861  13.366  1.00 32.74  ? 413  TYR B CA    1 
ATOM   6566  C C     . TYR B 1 413 ? 0.294    -54.108  14.366  1.00 39.50  ? 413  TYR B C     1 
ATOM   6567  O O     . TYR B 1 413 ? 0.644    -52.942  14.150  1.00 39.18  ? 413  TYR B O     1 
ATOM   6568  C CB    . TYR B 1 413 ? 0.317    -55.654  12.420  1.00 28.70  ? 413  TYR B CB    1 
ATOM   6569  C CG    . TYR B 1 413 ? -0.516   -56.690  11.705  1.00 30.56  ? 413  TYR B CG    1 
ATOM   6570  C CD1   . TYR B 1 413 ? -1.007   -57.806  12.386  1.00 28.70  ? 413  TYR B CD1   1 
ATOM   6571  C CD2   . TYR B 1 413 ? -0.871   -56.524  10.374  1.00 28.39  ? 413  TYR B CD2   1 
ATOM   6572  C CE1   . TYR B 1 413 ? -1.801   -58.749  11.744  1.00 27.64  ? 413  TYR B CE1   1 
ATOM   6573  C CE2   . TYR B 1 413 ? -1.664   -57.459  9.724   1.00 28.01  ? 413  TYR B CE2   1 
ATOM   6574  C CZ    . TYR B 1 413 ? -2.126   -58.571  10.412  1.00 26.51  ? 413  TYR B CZ    1 
ATOM   6575  O OH    . TYR B 1 413 ? -2.880   -59.496  9.765   1.00 22.61  ? 413  TYR B OH    1 
ATOM   6576  N N     . GLU B 1 414 ? 0.631    -54.813  15.452  1.00 52.35  ? 414  GLU B N     1 
ATOM   6577  C CA    . GLU B 1 414 ? 1.649    -54.383  16.399  1.00 64.95  ? 414  GLU B CA    1 
ATOM   6578  C C     . GLU B 1 414 ? 3.036    -54.376  15.731  1.00 62.68  ? 414  GLU B C     1 
ATOM   6579  O O     . GLU B 1 414 ? 3.831    -53.558  16.183  1.00 60.88  ? 414  GLU B O     1 
ATOM   6580  C CB    . GLU B 1 414 ? 1.681    -55.230  17.671  1.00 60.34  ? 414  GLU B CB    1 
ATOM   6581  C CG    . GLU B 1 414 ? 0.500    -54.930  18.582  1.00 68.72  ? 414  GLU B CG    1 
ATOM   6582  C CD    . GLU B 1 414 ? 0.583    -55.664  19.911  1.00 87.79  ? 414  GLU B CD    1 
ATOM   6583  O OE1   . GLU B 1 414 ? -0.238   -55.288  20.777  1.00 87.38  ? 414  GLU B OE1   1 
ATOM   6584  O OE2   . GLU B 1 414 ? 1.424    -56.591  20.094  1.00 85.36  ? 414  GLU B OE2   1 
ATOM   6585  O OXT   . GLU B 1 414 ? 3.280    -55.184  14.803  1.00 60.05  ? 414  GLU B OXT   1 
ATOM   6586  N N     . THR C 1 2   ? -18.383  -94.816  -32.398 1.00 58.90  ? 2    THR C N     1 
ATOM   6587  C CA    . THR C 1 2   ? -17.942  -96.197  -32.488 1.00 76.24  ? 2    THR C CA    1 
ATOM   6588  C C     . THR C 1 2   ? -18.815  -97.050  -31.631 1.00 75.03  ? 2    THR C C     1 
ATOM   6589  O O     . THR C 1 2   ? -19.217  -96.656  -30.570 1.00 72.94  ? 2    THR C O     1 
ATOM   6590  C CB    . THR C 1 2   ? -16.523  -96.405  -31.966 1.00 80.20  ? 2    THR C CB    1 
ATOM   6591  O OG1   . THR C 1 2   ? -15.692  -95.333  -32.378 1.00 77.54  ? 2    THR C OG1   1 
ATOM   6592  C CG2   . THR C 1 2   ? -15.964  -97.680  -32.503 1.00 74.59  ? 2    THR C CG2   1 
ATOM   6593  N N     . GLU C 1 3   ? -19.143  -98.219  -32.124 1.00 74.00  ? 3    GLU C N     1 
ATOM   6594  C CA    . GLU C 1 3   ? -19.961  -99.124  -31.382 1.00 66.95  ? 3    GLU C CA    1 
ATOM   6595  C C     . GLU C 1 3   ? -19.117  -99.802  -30.337 1.00 63.79  ? 3    GLU C C     1 
ATOM   6596  O O     . GLU C 1 3   ? -17.948  -100.023 -30.544 1.00 64.93  ? 3    GLU C O     1 
ATOM   6597  C CB    . GLU C 1 3   ? -20.533  -100.145 -32.332 1.00 71.14  ? 3    GLU C CB    1 
ATOM   6598  C CG    . GLU C 1 3   ? -21.944  -100.542 -32.005 1.00 95.77  ? 3    GLU C CG    1 
ATOM   6599  C CD    . GLU C 1 3   ? -22.432  -101.678 -32.853 1.00 105.26 ? 3    GLU C CD    1 
ATOM   6600  O OE1   . GLU C 1 3   ? -21.696  -102.063 -33.780 1.00 104.10 ? 3    GLU C OE1   1 
ATOM   6601  O OE2   . GLU C 1 3   ? -23.552  -102.173 -32.593 1.00 101.24 ? 3    GLU C OE2   1 
ATOM   6602  N N     . PRO C 1 4   ? -19.692  -100.099 -29.188 1.00 53.27  ? 4    PRO C N     1 
ATOM   6603  C CA    . PRO C 1 4   ? -18.899  -100.795 -28.209 1.00 48.46  ? 4    PRO C CA    1 
ATOM   6604  C C     . PRO C 1 4   ? -18.635  -102.230 -28.566 1.00 42.44  ? 4    PRO C C     1 
ATOM   6605  O O     . PRO C 1 4   ? -19.397  -102.863 -29.240 1.00 43.14  ? 4    PRO C O     1 
ATOM   6606  C CB    . PRO C 1 4   ? -19.777  -100.738 -26.969 1.00 49.39  ? 4    PRO C CB    1 
ATOM   6607  C CG    . PRO C 1 4   ? -21.116  -100.451 -27.453 1.00 39.86  ? 4    PRO C CG    1 
ATOM   6608  C CD    . PRO C 1 4   ? -20.901  -99.549  -28.585 1.00 48.87  ? 4    PRO C CD    1 
ATOM   6609  N N     . LEU C 1 5   ? -17.548  -102.748 -28.049 1.00 35.64  ? 5    LEU C N     1 
ATOM   6610  C CA    . LEU C 1 5   ? -17.179  -104.129 -28.221 1.00 38.38  ? 5    LEU C CA    1 
ATOM   6611  C C     . LEU C 1 5   ? -18.160  -105.035 -27.509 1.00 40.09  ? 5    LEU C C     1 
ATOM   6612  O O     . LEU C 1 5   ? -18.721  -104.690 -26.518 1.00 41.91  ? 5    LEU C O     1 
ATOM   6613  C CB    . LEU C 1 5   ? -15.807  -104.368 -27.630 1.00 37.17  ? 5    LEU C CB    1 
ATOM   6614  C CG    . LEU C 1 5   ? -14.599  -103.720 -28.254 1.00 38.01  ? 5    LEU C CG    1 
ATOM   6615  C CD1   . LEU C 1 5   ? -13.411  -103.859 -27.352 1.00 40.85  ? 5    LEU C CD1   1 
ATOM   6616  C CD2   . LEU C 1 5   ? -14.308  -104.350 -29.571 1.00 35.71  ? 5    LEU C CD2   1 
ATOM   6617  N N     . PRO C 1 6   ? -18.364  -106.219 -28.020 1.00 39.50  ? 6    PRO C N     1 
ATOM   6618  C CA    . PRO C 1 6   ? -19.294  -107.115 -27.331 1.00 40.42  ? 6    PRO C CA    1 
ATOM   6619  C C     . PRO C 1 6   ? -19.186  -107.138 -25.802 1.00 36.86  ? 6    PRO C C     1 
ATOM   6620  O O     . PRO C 1 6   ? -20.197  -107.150 -25.098 1.00 39.77  ? 6    PRO C O     1 
ATOM   6621  C CB    . PRO C 1 6   ? -19.108  -108.499 -28.024 1.00 36.27  ? 6    PRO C CB    1 
ATOM   6622  C CG    . PRO C 1 6   ? -18.705  -108.050 -29.432 1.00 35.87  ? 6    PRO C CG    1 
ATOM   6623  C CD    . PRO C 1 6   ? -17.837  -106.797 -29.266 1.00 36.25  ? 6    PRO C CD    1 
ATOM   6624  N N     . ARG C 1 7   ? -17.964  -107.210 -25.270 1.00 33.43  ? 7    ARG C N     1 
ATOM   6625  C CA    . ARG C 1 7   ? -17.824  -107.440 -23.838 1.00 31.76  ? 7    ARG C CA    1 
ATOM   6626  C C     . ARG C 1 7   ? -18.258  -106.172 -23.090 1.00 31.50  ? 7    ARG C C     1 
ATOM   6627  O O     . ARG C 1 7   ? -18.750  -106.264 -21.963 1.00 26.11  ? 7    ARG C O     1 
ATOM   6628  C CB    . ARG C 1 7   ? -16.421  -107.903 -23.416 1.00 31.93  ? 7    ARG C CB    1 
ATOM   6629  C CG    . ARG C 1 7   ? -15.309  -106.858 -23.578 1.00 31.06  ? 7    ARG C CG    1 
ATOM   6630  C CD    . ARG C 1 7   ? -13.989  -107.253 -22.896 1.00 29.57  ? 7    ARG C CD    1 
ATOM   6631  N NE    . ARG C 1 7   ? -12.963  -106.239 -23.175 1.00 33.05  ? 7    ARG C NE    1 
ATOM   6632  C CZ    . ARG C 1 7   ? -12.333  -106.081 -24.344 1.00 36.69  ? 7    ARG C CZ    1 
ATOM   6633  N NH1   . ARG C 1 7   ? -12.519  -107.019 -25.281 1.00 28.45  ? 7    ARG C NH1   1 
ATOM   6634  N NH2   . ARG C 1 7   ? -11.543  -105.017 -24.570 1.00 30.13  ? 7    ARG C NH2   1 
ATOM   6635  N N     . ILE C 1 8   ? -18.110  -105.007 -23.740 1.00 26.29  ? 8    ILE C N     1 
ATOM   6636  C CA    . ILE C 1 8   ? -18.501  -103.734 -23.164 1.00 28.86  ? 8    ILE C CA    1 
ATOM   6637  C C     . ILE C 1 8   ? -20.022  -103.534 -23.229 1.00 35.38  ? 8    ILE C C     1 
ATOM   6638  O O     . ILE C 1 8   ? -20.614  -103.054 -22.254 1.00 36.89  ? 8    ILE C O     1 
ATOM   6639  C CB    . ILE C 1 8   ? -17.674  -102.587 -23.767 1.00 26.28  ? 8    ILE C CB    1 
ATOM   6640  C CG1   . ILE C 1 8   ? -16.183  -102.764 -23.409 1.00 24.93  ? 8    ILE C CG1   1 
ATOM   6641  C CG2   . ILE C 1 8   ? -18.209  -101.229 -23.298 1.00 26.44  ? 8    ILE C CG2   1 
ATOM   6642  C CD1   . ILE C 1 8   ? -15.265  -101.694 -23.966 1.00 24.74  ? 8    ILE C CD1   1 
ATOM   6643  N N     . GLN C 1 9   ? -20.653  -103.947 -24.342 1.00 34.96  ? 9    GLN C N     1 
ATOM   6644  C CA    . GLN C 1 9   ? -22.101  -104.006 -24.439 1.00 37.22  ? 9    GLN C CA    1 
ATOM   6645  C C     . GLN C 1 9   ? -22.649  -104.866 -23.303 1.00 36.59  ? 9    GLN C C     1 
ATOM   6646  O O     . GLN C 1 9   ? -23.639  -104.488 -22.664 1.00 39.22  ? 9    GLN C O     1 
ATOM   6647  C CB    . GLN C 1 9   ? -22.608  -104.658 -25.725 1.00 46.31  ? 9    GLN C CB    1 
ATOM   6648  C CG    . GLN C 1 9   ? -23.062  -103.704 -26.825 1.00 71.31  ? 9    GLN C CG    1 
ATOM   6649  C CD    . GLN C 1 9   ? -22.965  -104.316 -28.217 1.00 90.87  ? 9    GLN C CD    1 
ATOM   6650  O OE1   . GLN C 1 9   ? -22.320  -103.754 -29.116 1.00 91.82  ? 9    GLN C OE1   1 
ATOM   6651  N NE2   . GLN C 1 9   ? -23.570  -105.485 -28.416 1.00 77.30  ? 9    GLN C NE2   1 
ATOM   6652  N N     . HIS C 1 10  ? -22.011  -106.022 -23.061 1.00 31.63  ? 10   HIS C N     1 
ATOM   6653  C CA    . HIS C 1 10  ? -22.485  -106.915 -22.020 1.00 33.25  ? 10   HIS C CA    1 
ATOM   6654  C C     . HIS C 1 10  ? -22.348  -106.221 -20.654 1.00 32.78  ? 10   HIS C C     1 
ATOM   6655  O O     . HIS C 1 10  ? -23.229  -106.351 -19.800 1.00 29.47  ? 10   HIS C O     1 
ATOM   6656  C CB    . HIS C 1 10  ? -21.864  -108.319 -22.130 1.00 33.43  ? 10   HIS C CB    1 
ATOM   6657  C CG    . HIS C 1 10  ? -22.426  -109.281 -21.122 1.00 48.96  ? 10   HIS C CG    1 
ATOM   6658  N ND1   . HIS C 1 10  ? -23.776  -109.541 -20.960 1.00 63.36  ? 10   HIS C ND1   1 
ATOM   6659  C CD2   . HIS C 1 10  ? -21.812  -110.032 -20.191 1.00 56.46  ? 10   HIS C CD2   1 
ATOM   6660  C CE1   . HIS C 1 10  ? -23.961  -110.424 -19.977 1.00 58.88  ? 10   HIS C CE1   1 
ATOM   6661  N NE2   . HIS C 1 10  ? -22.782  -110.738 -19.486 1.00 56.78  ? 10   HIS C NE2   1 
ATOM   6662  N N     . TYR C 1 11  ? -21.252  -105.462 -20.485 1.00 25.85  ? 11   TYR C N     1 
ATOM   6663  C CA    . TYR C 1 11  ? -20.972  -104.767 -19.249 1.00 28.06  ? 11   TYR C CA    1 
ATOM   6664  C C     . TYR C 1 11  ? -22.080  -103.748 -18.948 1.00 29.86  ? 11   TYR C C     1 
ATOM   6665  O O     . TYR C 1 11  ? -22.591  -103.700 -17.832 1.00 27.17  ? 11   TYR C O     1 
ATOM   6666  C CB    . TYR C 1 11  ? -19.577  -104.128 -19.307 1.00 25.82  ? 11   TYR C CB    1 
ATOM   6667  C CG    . TYR C 1 11  ? -19.344  -103.207 -18.130 1.00 24.99  ? 11   TYR C CG    1 
ATOM   6668  C CD1   . TYR C 1 11  ? -18.942  -103.714 -16.895 1.00 27.67  ? 11   TYR C CD1   1 
ATOM   6669  C CD2   . TYR C 1 11  ? -19.588  -101.840 -18.237 1.00 25.36  ? 11   TYR C CD2   1 
ATOM   6670  C CE1   . TYR C 1 11  ? -18.759  -102.875 -15.803 1.00 24.48  ? 11   TYR C CE1   1 
ATOM   6671  C CE2   . TYR C 1 11  ? -19.439  -100.994 -17.147 1.00 24.82  ? 11   TYR C CE2   1 
ATOM   6672  C CZ    . TYR C 1 11  ? -19.006  -101.517 -15.937 1.00 25.56  ? 11   TYR C CZ    1 
ATOM   6673  O OH    . TYR C 1 11  ? -18.840  -100.677 -14.876 1.00 26.40  ? 11   TYR C OH    1 
ATOM   6674  N N     . GLU C 1 12  ? -22.455  -102.945 -19.955 1.00 29.61  ? 12   GLU C N     1 
ATOM   6675  C CA    . GLU C 1 12  ? -23.470  -101.919 -19.766 1.00 28.75  ? 12   GLU C CA    1 
ATOM   6676  C C     . GLU C 1 12  ? -24.830  -102.533 -19.423 1.00 28.75  ? 12   GLU C C     1 
ATOM   6677  O O     . GLU C 1 12  ? -25.645  -101.878 -18.776 1.00 27.13  ? 12   GLU C O     1 
ATOM   6678  C CB    . GLU C 1 12  ? -23.569  -100.982 -20.965 1.00 24.75  ? 12   GLU C CB    1 
ATOM   6679  C CG    . GLU C 1 12  ? -22.258  -100.251 -21.244 1.00 27.97  ? 12   GLU C CG    1 
ATOM   6680  C CD    . GLU C 1 12  ? -22.384  -99.184  -22.310 1.00 35.60  ? 12   GLU C CD    1 
ATOM   6681  O OE1   . GLU C 1 12  ? -22.973  -99.491  -23.388 1.00 47.33  ? 12   GLU C OE1   1 
ATOM   6682  O OE2   . GLU C 1 12  ? -21.870  -98.043  -22.065 1.00 39.45  ? 12   GLU C OE2   1 
ATOM   6683  N N     . ASP C 1 13  ? -25.053  -103.790 -19.822 1.00 26.64  ? 13   ASP C N     1 
ATOM   6684  C CA    . ASP C 1 13  ? -26.302  -104.466 -19.516 1.00 27.78  ? 13   ASP C CA    1 
ATOM   6685  C C     . ASP C 1 13  ? -26.328  -104.960 -18.082 1.00 27.69  ? 13   ASP C C     1 
ATOM   6686  O O     . ASP C 1 13  ? -27.391  -105.365 -17.609 1.00 31.80  ? 13   ASP C O     1 
ATOM   6687  C CB    . ASP C 1 13  ? -26.563  -105.671 -20.410 1.00 29.34  ? 13   ASP C CB    1 
ATOM   6688  C CG    . ASP C 1 13  ? -27.123  -105.354 -21.792 1.00 35.70  ? 13   ASP C CG    1 
ATOM   6689  O OD1   . ASP C 1 13  ? -27.535  -104.168 -22.022 1.00 36.55  ? 13   ASP C OD1   1 
ATOM   6690  O OD2   . ASP C 1 13  ? -27.124  -106.282 -22.640 1.00 39.26  ? 13   ASP C OD2   1 
ATOM   6691  N N     . LEU C 1 14  ? -25.157  -105.004 -17.424 1.00 27.96  ? 14   LEU C N     1 
ATOM   6692  C CA    . LEU C 1 14  ? -25.124  -105.500 -16.056 1.00 27.81  ? 14   LEU C CA    1 
ATOM   6693  C C     . LEU C 1 14  ? -25.863  -104.502 -15.144 1.00 25.97  ? 14   LEU C C     1 
ATOM   6694  O O     . LEU C 1 14  ? -26.582  -104.909 -14.232 1.00 25.95  ? 14   LEU C O     1 
ATOM   6695  C CB    . LEU C 1 14  ? -23.677  -105.688 -15.620 1.00 26.04  ? 14   LEU C CB    1 
ATOM   6696  C CG    . LEU C 1 14  ? -22.834  -106.680 -16.413 1.00 28.25  ? 14   LEU C CG    1 
ATOM   6697  C CD1   . LEU C 1 14  ? -21.401  -106.559 -15.910 1.00 29.66  ? 14   LEU C CD1   1 
ATOM   6698  C CD2   . LEU C 1 14  ? -23.345  -108.109 -16.274 1.00 23.10  ? 14   LEU C CD2   1 
ATOM   6699  N N     . GLY C 1 15  ? -25.662  -103.196 -15.394 1.00 23.96  ? 15   GLY C N     1 
ATOM   6700  C CA    . GLY C 1 15  ? -26.407  -102.147 -14.712 1.00 25.99  ? 15   GLY C CA    1 
ATOM   6701  C C     . GLY C 1 15  ? -25.907  -101.891 -13.289 1.00 25.41  ? 15   GLY C C     1 
ATOM   6702  O O     . GLY C 1 15  ? -25.366  -100.824 -12.992 1.00 26.44  ? 15   GLY C O     1 
ATOM   6703  N N     . LEU C 1 16  ? -26.088  -102.892 -12.424 1.00 22.55  ? 16   LEU C N     1 
ATOM   6704  C CA    . LEU C 1 16  ? -25.858  -102.751 -11.002 1.00 22.71  ? 16   LEU C CA    1 
ATOM   6705  C C     . LEU C 1 16  ? -24.906  -103.860 -10.545 1.00 23.43  ? 16   LEU C C     1 
ATOM   6706  O O     . LEU C 1 16  ? -25.101  -105.051 -10.852 1.00 23.25  ? 16   LEU C O     1 
ATOM   6707  C CB    . LEU C 1 16  ? -27.217  -102.850 -10.296 1.00 23.58  ? 16   LEU C CB    1 
ATOM   6708  C CG    . LEU C 1 16  ? -27.162  -103.044 -8.765  1.00 23.35  ? 16   LEU C CG    1 
ATOM   6709  C CD1   . LEU C 1 16  ? -26.582  -101.856 -8.003  1.00 23.04  ? 16   LEU C CD1   1 
ATOM   6710  C CD2   . LEU C 1 16  ? -28.505  -103.398 -8.176  1.00 19.70  ? 16   LEU C CD2   1 
ATOM   6711  N N     . GLY C 1 17  ? -23.881  -103.456 -9.797  1.00 23.34  ? 17   GLY C N     1 
ATOM   6712  C CA    . GLY C 1 17  ? -23.003  -104.421 -9.149  1.00 21.66  ? 17   GLY C CA    1 
ATOM   6713  C C     . GLY C 1 17  ? -22.909  -104.159 -7.641  1.00 23.31  ? 17   GLY C C     1 
ATOM   6714  O O     . GLY C 1 17  ? -23.166  -103.052 -7.153  1.00 23.67  ? 17   GLY C O     1 
ATOM   6715  N N     . LEU C 1 18  ? -22.491  -105.187 -6.916  1.00 23.06  ? 18   LEU C N     1 
ATOM   6716  C CA    . LEU C 1 18  ? -22.191  -105.050 -5.506  1.00 25.19  ? 18   LEU C CA    1 
ATOM   6717  C C     . LEU C 1 18  ? -20.674  -104.954 -5.319  1.00 27.23  ? 18   LEU C C     1 
ATOM   6718  O O     . LEU C 1 18  ? -19.930  -105.779 -5.859  1.00 25.50  ? 18   LEU C O     1 
ATOM   6719  C CB    . LEU C 1 18  ? -22.765  -106.333 -4.921  1.00 25.43  ? 18   LEU C CB    1 
ATOM   6720  C CG    . LEU C 1 18  ? -22.861  -106.320 -3.399  1.00 34.80  ? 18   LEU C CG    1 
ATOM   6721  C CD1   . LEU C 1 18  ? -23.873  -105.231 -3.035  1.00 35.79  ? 18   LEU C CD1   1 
ATOM   6722  C CD2   . LEU C 1 18  ? -23.245  -107.703 -2.880  1.00 34.54  ? 18   LEU C CD2   1 
ATOM   6723  N N     . PHE C 1 19  ? -20.227  -103.913 -4.600  1.00 23.92  ? 19   PHE C N     1 
ATOM   6724  C CA    . PHE C 1 19  ? -18.826  -103.725 -4.261  1.00 22.96  ? 19   PHE C CA    1 
ATOM   6725  C C     . PHE C 1 19  ? -18.625  -104.248 -2.849  1.00 22.79  ? 19   PHE C C     1 
ATOM   6726  O O     . PHE C 1 19  ? -19.429  -103.922 -1.966  1.00 20.81  ? 19   PHE C O     1 
ATOM   6727  C CB    . PHE C 1 19  ? -18.526  -102.222 -4.253  1.00 23.90  ? 19   PHE C CB    1 
ATOM   6728  C CG    . PHE C 1 19  ? -17.127  -101.780 -4.659  1.00 24.32  ? 19   PHE C CG    1 
ATOM   6729  C CD1   . PHE C 1 19  ? -16.026  -102.640 -4.526  1.00 25.25  ? 19   PHE C CD1   1 
ATOM   6730  C CD2   . PHE C 1 19  ? -16.899  -100.484 -5.135  1.00 25.43  ? 19   PHE C CD2   1 
ATOM   6731  C CE1   . PHE C 1 19  ? -14.736  -102.237 -4.877  1.00 22.05  ? 19   PHE C CE1   1 
ATOM   6732  C CE2   . PHE C 1 19  ? -15.619  -100.081 -5.515  1.00 26.09  ? 19   PHE C CE2   1 
ATOM   6733  C CZ    . PHE C 1 19  ? -14.538  -100.963 -5.392  1.00 25.98  ? 19   PHE C CZ    1 
ATOM   6734  N N     . ILE C 1 20  ? -17.560  -105.056 -2.633  1.00 24.44  ? 20   ILE C N     1 
ATOM   6735  C CA    . ILE C 1 20  ? -17.317  -105.621 -1.304  1.00 22.59  ? 20   ILE C CA    1 
ATOM   6736  C C     . ILE C 1 20  ? -15.897  -105.327 -0.840  1.00 23.62  ? 20   ILE C C     1 
ATOM   6737  O O     . ILE C 1 20  ? -14.936  -105.732 -1.502  1.00 26.55  ? 20   ILE C O     1 
ATOM   6738  C CB    . ILE C 1 20  ? -17.599  -107.133 -1.315  1.00 24.15  ? 20   ILE C CB    1 
ATOM   6739  C CG1   . ILE C 1 20  ? -19.072  -107.377 -1.692  1.00 24.27  ? 20   ILE C CG1   1 
ATOM   6740  C CG2   . ILE C 1 20  ? -17.213  -107.760 0.033   1.00 22.10  ? 20   ILE C CG2   1 
ATOM   6741  C CD1   . ILE C 1 20  ? -19.438  -108.829 -1.686  1.00 27.43  ? 20   ILE C CD1   1 
ATOM   6742  N N     . HIS C 1 21  ? -15.783  -104.615 0.293   1.00 21.53  ? 21   HIS C N     1 
ATOM   6743  C CA    . HIS C 1 21  ? -14.512  -104.297 0.916   1.00 19.89  ? 21   HIS C CA    1 
ATOM   6744  C C     . HIS C 1 21  ? -14.336  -105.200 2.124   1.00 22.13  ? 21   HIS C C     1 
ATOM   6745  O O     . HIS C 1 21  ? -15.137  -105.175 3.086   1.00 25.13  ? 21   HIS C O     1 
ATOM   6746  C CB    . HIS C 1 21  ? -14.462  -102.836 1.381   1.00 19.59  ? 21   HIS C CB    1 
ATOM   6747  C CG    . HIS C 1 21  ? -14.095  -101.925 0.249   1.00 23.13  ? 21   HIS C CG    1 
ATOM   6748  N ND1   . HIS C 1 21  ? -14.970  -101.634 -0.787  1.00 22.52  ? 21   HIS C ND1   1 
ATOM   6749  C CD2   . HIS C 1 21  ? -12.948  -101.275 -0.042  1.00 21.43  ? 21   HIS C CD2   1 
ATOM   6750  C CE1   . HIS C 1 21  ? -14.373  -100.826 -1.663  1.00 21.41  ? 21   HIS C CE1   1 
ATOM   6751  N NE2   . HIS C 1 21  ? -13.144  -100.600 -1.232  1.00 20.68  ? 21   HIS C NE2   1 
ATOM   6752  N N     . TRP C 1 22  ? -13.270  -105.999 2.061   1.00 21.83  ? 22   TRP C N     1 
ATOM   6753  C CA    . TRP C 1 22  ? -12.942  -106.877 3.173   1.00 22.79  ? 22   TRP C CA    1 
ATOM   6754  C C     . TRP C 1 22  ? -11.439  -107.119 3.152   1.00 25.85  ? 22   TRP C C     1 
ATOM   6755  O O     . TRP C 1 22  ? -10.898  -107.508 2.109   1.00 24.05  ? 22   TRP C O     1 
ATOM   6756  C CB    . TRP C 1 22  ? -13.687  -108.195 2.973   1.00 20.43  ? 22   TRP C CB    1 
ATOM   6757  C CG    . TRP C 1 22  ? -13.487  -109.173 4.092   1.00 24.37  ? 22   TRP C CG    1 
ATOM   6758  C CD1   . TRP C 1 22  ? -13.357  -108.919 5.431   1.00 24.57  ? 22   TRP C CD1   1 
ATOM   6759  C CD2   . TRP C 1 22  ? -13.412  -110.604 3.938   1.00 22.04  ? 22   TRP C CD2   1 
ATOM   6760  N NE1   . TRP C 1 22  ? -13.224  -110.096 6.126   1.00 24.25  ? 22   TRP C NE1   1 
ATOM   6761  C CE2   . TRP C 1 22  ? -13.239  -111.141 5.235   1.00 24.04  ? 22   TRP C CE2   1 
ATOM   6762  C CE3   . TRP C 1 22  ? -13.460  -111.467 2.832   1.00 24.09  ? 22   TRP C CE3   1 
ATOM   6763  C CZ2   . TRP C 1 22  ? -13.115  -112.509 5.451   1.00 23.00  ? 22   TRP C CZ2   1 
ATOM   6764  C CZ3   . TRP C 1 22  ? -13.342  -112.825 3.040   1.00 23.64  ? 22   TRP C CZ3   1 
ATOM   6765  C CH2   . TRP C 1 22  ? -13.177  -113.329 4.336   1.00 24.97  ? 22   TRP C CH2   1 
ATOM   6766  N N     . GLY C 1 23  ? -10.786  -106.879 4.295   1.00 23.91  ? 23   GLY C N     1 
ATOM   6767  C CA    . GLY C 1 23  ? -9.361   -107.109 4.434   1.00 24.68  ? 23   GLY C CA    1 
ATOM   6768  C C     . GLY C 1 23  ? -8.993   -107.164 5.909   1.00 27.07  ? 23   GLY C C     1 
ATOM   6769  O O     . GLY C 1 23  ? -9.876   -107.309 6.745   1.00 27.07  ? 23   GLY C O     1 
ATOM   6770  N N     . LEU C 1 24  ? -7.698   -107.040 6.234   1.00 27.15  ? 24   LEU C N     1 
ATOM   6771  C CA    . LEU C 1 24  ? -7.302   -107.098 7.636   1.00 24.62  ? 24   LEU C CA    1 
ATOM   6772  C C     . LEU C 1 24  ? -7.920   -105.915 8.373   1.00 24.18  ? 24   LEU C C     1 
ATOM   6773  O O     . LEU C 1 24  ? -8.294   -106.051 9.531   1.00 25.77  ? 24   LEU C O     1 
ATOM   6774  C CB    . LEU C 1 24  ? -5.780   -107.142 7.808   1.00 24.49  ? 24   LEU C CB    1 
ATOM   6775  C CG    . LEU C 1 24  ? -5.041   -108.295 7.119   1.00 25.81  ? 24   LEU C CG    1 
ATOM   6776  C CD1   . LEU C 1 24  ? -3.532   -108.138 7.285   1.00 27.11  ? 24   LEU C CD1   1 
ATOM   6777  C CD2   . LEU C 1 24  ? -5.559   -109.658 7.549   1.00 23.65  ? 24   LEU C CD2   1 
ATOM   6778  N N     . TYR C 1 25  ? -8.044   -104.766 7.687   1.00 21.27  ? 25   TYR C N     1 
ATOM   6779  C CA    . TYR C 1 25  ? -8.604   -103.554 8.261   1.00 21.02  ? 25   TYR C CA    1 
ATOM   6780  C C     . TYR C 1 25  ? -9.978   -103.823 8.875   1.00 23.33  ? 25   TYR C C     1 
ATOM   6781  O O     . TYR C 1 25  ? -10.354  -103.170 9.847   1.00 25.34  ? 25   TYR C O     1 
ATOM   6782  C CB    . TYR C 1 25  ? -8.756   -102.427 7.242   1.00 22.14  ? 25   TYR C CB    1 
ATOM   6783  C CG    . TYR C 1 25  ? -9.301   -102.882 5.895   1.00 24.52  ? 25   TYR C CG    1 
ATOM   6784  C CD1   . TYR C 1 25  ? -10.676  -103.021 5.672   1.00 26.95  ? 25   TYR C CD1   1 
ATOM   6785  C CD2   . TYR C 1 25  ? -8.440   -103.148 4.834   1.00 20.72  ? 25   TYR C CD2   1 
ATOM   6786  C CE1   . TYR C 1 25  ? -11.172  -103.415 4.435   1.00 23.75  ? 25   TYR C CE1   1 
ATOM   6787  C CE2   . TYR C 1 25  ? -8.914   -103.553 3.597   1.00 22.71  ? 25   TYR C CE2   1 
ATOM   6788  C CZ    . TYR C 1 25  ? -10.293  -103.686 3.390   1.00 25.85  ? 25   TYR C CZ    1 
ATOM   6789  O OH    . TYR C 1 25  ? -10.781  -104.121 2.179   1.00 21.15  ? 25   TYR C OH    1 
ATOM   6790  N N     . SER C 1 26  ? -10.729  -104.781 8.319   1.00 22.23  ? 26   SER C N     1 
ATOM   6791  C CA    . SER C 1 26  ? -12.088  -105.052 8.765   1.00 21.43  ? 26   SER C CA    1 
ATOM   6792  C C     . SER C 1 26  ? -12.118  -105.421 10.248  1.00 26.08  ? 26   SER C C     1 
ATOM   6793  O O     . SER C 1 26  ? -13.095  -105.157 10.963  1.00 25.27  ? 26   SER C O     1 
ATOM   6794  C CB    . SER C 1 26  ? -12.747  -106.111 7.931   1.00 21.18  ? 26   SER C CB    1 
ATOM   6795  O OG    . SER C 1 26  ? -12.679  -105.767 6.544   1.00 23.42  ? 26   SER C OG    1 
ATOM   6796  N N     . GLN C 1 27  ? -11.031  -106.034 10.734  1.00 28.03  ? 27   GLN C N     1 
ATOM   6797  C CA    . GLN C 1 27  ? -11.013  -106.419 12.136  1.00 26.73  ? 27   GLN C CA    1 
ATOM   6798  C C     . GLN C 1 27  ? -11.026  -105.209 13.067  1.00 25.55  ? 27   GLN C C     1 
ATOM   6799  O O     . GLN C 1 27  ? -11.445  -105.355 14.193  1.00 25.42  ? 27   GLN C O     1 
ATOM   6800  C CB    . GLN C 1 27  ? -9.845   -107.308 12.517  1.00 24.30  ? 27   GLN C CB    1 
ATOM   6801  C CG    . GLN C 1 27  ? -10.024  -108.734 12.009  1.00 28.84  ? 27   GLN C CG    1 
ATOM   6802  C CD    . GLN C 1 27  ? -8.716   -109.486 12.082  1.00 30.30  ? 27   GLN C CD    1 
ATOM   6803  O OE1   . GLN C 1 27  ? -8.050   -109.740 11.066  1.00 31.72  ? 27   GLN C OE1   1 
ATOM   6804  N NE2   . GLN C 1 27  ? -8.309   -109.767 13.314  1.00 26.20  ? 27   GLN C NE2   1 
ATOM   6805  N N     . MET C 1 28  ? -10.605  -104.030 12.622  1.00 27.65  ? 28   MET C N     1 
ATOM   6806  C CA    . MET C 1 28  ? -10.553  -102.891 13.525  1.00 28.91  ? 28   MET C CA    1 
ATOM   6807  C C     . MET C 1 28  ? -11.803  -102.016 13.406  1.00 27.42  ? 28   MET C C     1 
ATOM   6808  O O     . MET C 1 28  ? -12.055  -101.206 14.295  1.00 25.37  ? 28   MET C O     1 
ATOM   6809  C CB    . MET C 1 28  ? -9.422   -101.965 13.112  1.00 34.13  ? 28   MET C CB    1 
ATOM   6810  C CG    . MET C 1 28  ? -8.170   -102.692 12.752  1.00 48.96  ? 28   MET C CG    1 
ATOM   6811  S SD    . MET C 1 28  ? -7.055   -102.548 14.144  1.00 68.98  ? 28   MET C SD    1 
ATOM   6812  C CE    . MET C 1 28  ? -7.812   -103.680 15.327  1.00 41.71  ? 28   MET C CE    1 
ATOM   6813  N N     . ALA C 1 29  ? -12.506  -102.086 12.261  1.00 25.67  ? 29   ALA C N     1 
ATOM   6814  C CA    . ALA C 1 29  ? -13.798  -101.418 12.092  1.00 24.28  ? 29   ALA C CA    1 
ATOM   6815  C C     . ALA C 1 29  ? -13.649  -99.904  12.252  1.00 21.54  ? 29   ALA C C     1 
ATOM   6816  O O     . ALA C 1 29  ? -14.525  -99.238  12.823  1.00 22.10  ? 29   ALA C O     1 
ATOM   6817  C CB    . ALA C 1 29  ? -14.849  -102.004 13.058  1.00 21.70  ? 29   ALA C CB    1 
ATOM   6818  N N     . VAL C 1 30  ? -12.545  -99.370  11.736  1.00 20.10  ? 30   VAL C N     1 
ATOM   6819  C CA    . VAL C 1 30  ? -12.345  -97.934  11.713  1.00 20.88  ? 30   VAL C CA    1 
ATOM   6820  C C     . VAL C 1 30  ? -11.885  -97.527  10.312  1.00 22.01  ? 30   VAL C C     1 
ATOM   6821  O O     . VAL C 1 30  ? -11.061  -96.624  10.181  1.00 24.30  ? 30   VAL C O     1 
ATOM   6822  C CB    . VAL C 1 30  ? -11.364  -97.427  12.822  1.00 23.55  ? 30   VAL C CB    1 
ATOM   6823  C CG1   . VAL C 1 30  ? -11.948  -97.505  14.233  1.00 19.66  ? 30   VAL C CG1   1 
ATOM   6824  C CG2   . VAL C 1 30  ? -10.010  -98.134  12.800  1.00 18.31  ? 30   VAL C CG2   1 
ATOM   6825  N N     . GLY C 1 31  ? -12.411  -98.163  9.252   1.00 22.16  ? 31   GLY C N     1 
ATOM   6826  C CA    . GLY C 1 31  ? -12.107  -97.706  7.889   1.00 21.34  ? 31   GLY C CA    1 
ATOM   6827  C C     . GLY C 1 31  ? -10.942  -98.486  7.260   1.00 23.67  ? 31   GLY C C     1 
ATOM   6828  O O     . GLY C 1 31  ? -10.031  -98.945  7.965   1.00 20.94  ? 31   GLY C O     1 
ATOM   6829  N N     . GLU C 1 32  ? -10.952  -98.612  5.925   1.00 24.76  ? 32   GLU C N     1 
ATOM   6830  C CA    . GLU C 1 32  ? -9.965   -99.427  5.220   1.00 23.04  ? 32   GLU C CA    1 
ATOM   6831  C C     . GLU C 1 32  ? -8.602   -98.721  5.154   1.00 27.47  ? 32   GLU C C     1 
ATOM   6832  O O     . GLU C 1 32  ? -7.589   -99.404  4.952   1.00 27.97  ? 32   GLU C O     1 
ATOM   6833  C CB    . GLU C 1 32  ? -10.453  -99.880  3.844   1.00 19.40  ? 32   GLU C CB    1 
ATOM   6834  C CG    . GLU C 1 32  ? -10.619  -98.751  2.835   1.00 20.16  ? 32   GLU C CG    1 
ATOM   6835  C CD    . GLU C 1 32  ? -11.729  -97.702  3.006   1.00 22.95  ? 32   GLU C CD    1 
ATOM   6836  O OE1   . GLU C 1 32  ? -12.575  -97.734  3.939   1.00 19.28  ? 32   GLU C OE1   1 
ATOM   6837  O OE2   . GLU C 1 32  ? -11.748  -96.781  2.143   1.00 20.93  ? 32   GLU C OE2   1 
ATOM   6838  N N     . TRP C 1 33  ? -8.558   -97.380  5.307   1.00 22.24  ? 33   TRP C N     1 
ATOM   6839  C CA    . TRP C 1 33  ? -7.286   -96.672  5.269   1.00 19.72  ? 33   TRP C CA    1 
ATOM   6840  C C     . TRP C 1 33  ? -6.622   -96.583  6.651   1.00 20.49  ? 33   TRP C C     1 
ATOM   6841  O O     . TRP C 1 33  ? -5.681   -95.792  6.825   1.00 22.24  ? 33   TRP C O     1 
ATOM   6842  C CB    . TRP C 1 33  ? -7.457   -95.258  4.699   1.00 19.59  ? 33   TRP C CB    1 
ATOM   6843  C CG    . TRP C 1 33  ? -7.514   -95.179  3.195   1.00 22.71  ? 33   TRP C CG    1 
ATOM   6844  C CD1   . TRP C 1 33  ? -8.497   -95.666  2.372   1.00 24.17  ? 33   TRP C CD1   1 
ATOM   6845  C CD2   . TRP C 1 33  ? -6.590   -94.491  2.320   1.00 21.73  ? 33   TRP C CD2   1 
ATOM   6846  N NE1   . TRP C 1 33  ? -8.231   -95.371  1.056   1.00 21.45  ? 33   TRP C NE1   1 
ATOM   6847  C CE2   . TRP C 1 33  ? -7.075   -94.636  0.994   1.00 23.54  ? 33   TRP C CE2   1 
ATOM   6848  C CE3   . TRP C 1 33  ? -5.413   -93.747  2.525   1.00 23.84  ? 33   TRP C CE3   1 
ATOM   6849  C CZ2   . TRP C 1 33  ? -6.417   -94.082  -0.114  1.00 22.31  ? 33   TRP C CZ2   1 
ATOM   6850  C CZ3   . TRP C 1 33  ? -4.767   -93.193  1.429   1.00 22.23  ? 33   TRP C CZ3   1 
ATOM   6851  C CH2   . TRP C 1 33  ? -5.289   -93.322  0.136   1.00 20.98  ? 33   TRP C CH2   1 
ATOM   6852  N N     . THR C 1 34  ? -7.085   -97.377  7.638   1.00 20.01  ? 34   THR C N     1 
ATOM   6853  C CA    . THR C 1 34  ? -6.662   -97.164  9.016   1.00 21.50  ? 34   THR C CA    1 
ATOM   6854  C C     . THR C 1 34  ? -5.124   -97.213  9.171   1.00 25.88  ? 34   THR C C     1 
ATOM   6855  O O     . THR C 1 34  ? -4.548   -96.405  9.903   1.00 24.15  ? 34   THR C O     1 
ATOM   6856  C CB    . THR C 1 34  ? -7.388   -98.121  9.957   1.00 22.51  ? 34   THR C CB    1 
ATOM   6857  O OG1   . THR C 1 34  ? -6.905   -97.805  11.248  1.00 20.97  ? 34   THR C OG1   1 
ATOM   6858  C CG2   . THR C 1 34  ? -7.070   -99.591  9.748   1.00 21.53  ? 34   THR C CG2   1 
ATOM   6859  N N     . GLU C 1 35  ? -4.449   -98.136  8.473   1.00 24.65  ? 35   GLU C N     1 
ATOM   6860  C CA    . GLU C 1 35  ? -3.016   -98.302  8.659   1.00 29.07  ? 35   GLU C CA    1 
ATOM   6861  C C     . GLU C 1 35  ? -2.258   -97.005  8.374   1.00 29.33  ? 35   GLU C C     1 
ATOM   6862  O O     . GLU C 1 35  ? -1.411   -96.605  9.180   1.00 27.56  ? 35   GLU C O     1 
ATOM   6863  C CB    . GLU C 1 35  ? -2.396   -99.472  7.900   1.00 30.10  ? 35   GLU C CB    1 
ATOM   6864  C CG    . GLU C 1 35  ? -0.907   -99.631  8.177   1.00 30.15  ? 35   GLU C CG    1 
ATOM   6865  C CD    . GLU C 1 35  ? -0.280   -100.763 7.372   1.00 37.07  ? 35   GLU C CD    1 
ATOM   6866  O OE1   . GLU C 1 35  ? -0.834   -101.191 6.314   1.00 33.32  ? 35   GLU C OE1   1 
ATOM   6867  O OE2   . GLU C 1 35  ? 0.776    -101.256 7.848   1.00 39.27  ? 35   GLU C OE2   1 
ATOM   6868  N N     . LEU C 1 36  ? -2.566   -96.346  7.254   1.00 28.12  ? 36   LEU C N     1 
ATOM   6869  C CA    . LEU C 1 36  ? -1.887   -95.111  6.908   1.00 24.67  ? 36   LEU C CA    1 
ATOM   6870  C C     . LEU C 1 36  ? -2.440   -93.958  7.754   1.00 29.94  ? 36   LEU C C     1 
ATOM   6871  O O     . LEU C 1 36  ? -1.669   -93.235  8.383   1.00 33.10  ? 36   LEU C O     1 
ATOM   6872  C CB    . LEU C 1 36  ? -1.996   -94.795  5.419   1.00 28.29  ? 36   LEU C CB    1 
ATOM   6873  C CG    . LEU C 1 36  ? -1.293   -93.511  4.939   1.00 32.08  ? 36   LEU C CG    1 
ATOM   6874  C CD1   . LEU C 1 36  ? 0.199    -93.717  5.066   1.00 37.04  ? 36   LEU C CD1   1 
ATOM   6875  C CD2   . LEU C 1 36  ? -1.531   -93.296  3.500   1.00 33.50  ? 36   LEU C CD2   1 
ATOM   6876  N N     . ILE C 1 37  ? -3.775   -93.774  7.787   1.00 28.73  ? 37   ILE C N     1 
ATOM   6877  C CA    . ILE C 1 37  ? -4.309   -92.527  8.320   1.00 27.45  ? 37   ILE C CA    1 
ATOM   6878  C C     . ILE C 1 37  ? -4.149   -92.456  9.838   1.00 27.02  ? 37   ILE C C     1 
ATOM   6879  O O     . ILE C 1 37  ? -3.961   -91.372  10.375  1.00 30.21  ? 37   ILE C O     1 
ATOM   6880  C CB    . ILE C 1 37  ? -5.745   -92.264  7.845   1.00 24.14  ? 37   ILE C CB    1 
ATOM   6881  C CG1   . ILE C 1 37  ? -5.739   -92.001  6.339   1.00 26.76  ? 37   ILE C CG1   1 
ATOM   6882  C CG2   . ILE C 1 37  ? -6.366   -91.089  8.601   1.00 18.77  ? 37   ILE C CG2   1 
ATOM   6883  C CD1   . ILE C 1 37  ? -7.129   -91.921  5.733   1.00 29.49  ? 37   ILE C CD1   1 
ATOM   6884  N N     . HIS C 1 38  ? -4.223   -93.597  10.534  1.00 25.82  ? 38   HIS C N     1 
ATOM   6885  C CA    . HIS C 1 38  ? -4.028   -93.596  11.969  1.00 27.65  ? 38   HIS C CA    1 
ATOM   6886  C C     . HIS C 1 38  ? -2.554   -93.827  12.328  1.00 32.66  ? 38   HIS C C     1 
ATOM   6887  O O     . HIS C 1 38  ? -2.269   -94.103  13.488  1.00 31.10  ? 38   HIS C O     1 
ATOM   6888  C CB    . HIS C 1 38  ? -4.888   -94.683  12.621  1.00 26.57  ? 38   HIS C CB    1 
ATOM   6889  C CG    . HIS C 1 38  ? -6.351   -94.374  12.586  1.00 30.12  ? 38   HIS C CG    1 
ATOM   6890  N ND1   . HIS C 1 38  ? -7.300   -95.254  12.093  1.00 28.61  ? 38   HIS C ND1   1 
ATOM   6891  C CD2   . HIS C 1 38  ? -7.026   -93.258  12.966  1.00 27.96  ? 38   HIS C CD2   1 
ATOM   6892  C CE1   . HIS C 1 38  ? -8.498   -94.704  12.193  1.00 30.58  ? 38   HIS C CE1   1 
ATOM   6893  N NE2   . HIS C 1 38  ? -8.359   -93.490  12.756  1.00 29.37  ? 38   HIS C NE2   1 
ATOM   6894  N N     . HIS C 1 39  ? -1.644   -93.760  11.335  1.00 35.60  ? 39   HIS C N     1 
ATOM   6895  C CA    . HIS C 1 39  ? -0.199   -93.800  11.536  1.00 42.20  ? 39   HIS C CA    1 
ATOM   6896  C C     . HIS C 1 39  ? 0.187    -95.026  12.364  1.00 37.68  ? 39   HIS C C     1 
ATOM   6897  O O     . HIS C 1 39  ? 0.881    -94.906  13.353  1.00 30.37  ? 39   HIS C O     1 
ATOM   6898  C CB    . HIS C 1 39  ? 0.339    -92.447  12.045  1.00 50.51  ? 39   HIS C CB    1 
ATOM   6899  C CG    . HIS C 1 39  ? 1.854    -92.324  12.021  1.00 94.53  ? 39   HIS C CG    1 
ATOM   6900  N ND1   . HIS C 1 39  ? 2.587    -92.207  10.851  1.00 106.19 ? 39   HIS C ND1   1 
ATOM   6901  C CD2   . HIS C 1 39  ? 2.782    -92.329  13.016  1.00 100.38 ? 39   HIS C CD2   1 
ATOM   6902  C CE1   . HIS C 1 39  ? 3.888    -92.120  11.124  1.00 88.60  ? 39   HIS C CE1   1 
ATOM   6903  N NE2   . HIS C 1 39  ? 4.027    -92.199  12.435  1.00 97.04  ? 39   HIS C NE2   1 
ATOM   6904  N N     . ARG C 1 40  ? -0.303   -96.215  11.999  1.00 34.48  ? 40   ARG C N     1 
ATOM   6905  C CA    . ARG C 1 40  ? -0.067   -97.362  12.863  1.00 31.43  ? 40   ARG C CA    1 
ATOM   6906  C C     . ARG C 1 40  ? 1.322    -97.933  12.595  1.00 30.94  ? 40   ARG C C     1 
ATOM   6907  O O     . ARG C 1 40  ? 1.872    -97.786  11.508  1.00 32.52  ? 40   ARG C O     1 
ATOM   6908  C CB    . ARG C 1 40  ? -1.104   -98.444  12.547  1.00 31.23  ? 40   ARG C CB    1 
ATOM   6909  C CG    . ARG C 1 40  ? -2.489   -98.047  13.003  1.00 35.11  ? 40   ARG C CG    1 
ATOM   6910  C CD    . ARG C 1 40  ? -3.427   -99.183  12.729  1.00 37.56  ? 40   ARG C CD    1 
ATOM   6911  N NE    . ARG C 1 40  ? -4.842   -98.891  12.953  1.00 47.63  ? 40   ARG C NE    1 
ATOM   6912  C CZ    . ARG C 1 40  ? -5.471   -98.820  14.129  1.00 50.48  ? 40   ARG C CZ    1 
ATOM   6913  N NH1   . ARG C 1 40  ? -4.801   -98.988  15.254  1.00 43.73  ? 40   ARG C NH1   1 
ATOM   6914  N NH2   . ARG C 1 40  ? -6.763   -98.536  14.170  1.00 45.03  ? 40   ARG C NH2   1 
ATOM   6915  N N     . ASN C 1 41  ? 1.881    -98.593  13.602  1.00 31.88  ? 41   ASN C N     1 
ATOM   6916  C CA    . ASN C 1 41  ? 3.092    -99.380  13.455  1.00 30.79  ? 41   ASN C CA    1 
ATOM   6917  C C     . ASN C 1 41  ? 2.829    -100.526 12.469  1.00 31.40  ? 41   ASN C C     1 
ATOM   6918  O O     . ASN C 1 41  ? 1.997    -101.419 12.722  1.00 29.59  ? 41   ASN C O     1 
ATOM   6919  C CB    . ASN C 1 41  ? 3.517    -99.916  14.829  1.00 37.87  ? 41   ASN C CB    1 
ATOM   6920  C CG    . ASN C 1 41  ? 4.738    -100.796 14.715  1.00 42.19  ? 41   ASN C CG    1 
ATOM   6921  O OD1   . ASN C 1 41  ? 5.855    -100.288 14.751  1.00 43.39  ? 41   ASN C OD1   1 
ATOM   6922  N ND2   . ASN C 1 41  ? 4.533    -102.100 14.594  1.00 41.38  ? 41   ASN C ND2   1 
ATOM   6923  N N     . GLN C 1 42  ? 3.600    -100.560 11.374  1.00 30.91  ? 42   GLN C N     1 
ATOM   6924  C CA    . GLN C 1 42  ? 3.368    -101.554 10.337  1.00 31.59  ? 42   GLN C CA    1 
ATOM   6925  C C     . GLN C 1 42  ? 3.413    -102.983 10.885  1.00 36.06  ? 42   GLN C C     1 
ATOM   6926  O O     . GLN C 1 42  ? 2.543    -103.810 10.580  1.00 44.63  ? 42   GLN C O     1 
ATOM   6927  C CB    . GLN C 1 42  ? 4.292    -101.362 9.148   1.00 26.80  ? 42   GLN C CB    1 
ATOM   6928  C CG    . GLN C 1 42  ? 4.032    -102.406 8.072   1.00 39.74  ? 42   GLN C CG    1 
ATOM   6929  C CD    . GLN C 1 42  ? 4.745    -102.076 6.776   1.00 45.23  ? 42   GLN C CD    1 
ATOM   6930  O OE1   . GLN C 1 42  ? 4.609    -102.774 5.777   1.00 49.24  ? 42   GLN C OE1   1 
ATOM   6931  N NE2   . GLN C 1 42  ? 5.531    -101.007 6.761   1.00 36.00  ? 42   GLN C NE2   1 
ATOM   6932  N N     . HIS C 1 43  ? 4.435    -103.278 11.696  1.00 36.21  ? 43   HIS C N     1 
ATOM   6933  C CA    . HIS C 1 43  ? 4.623    -104.628 12.198  1.00 34.34  ? 43   HIS C CA    1 
ATOM   6934  C C     . HIS C 1 43  ? 3.387    -105.049 12.998  1.00 32.44  ? 43   HIS C C     1 
ATOM   6935  O O     . HIS C 1 43  ? 2.929    -106.174 12.893  1.00 33.31  ? 43   HIS C O     1 
ATOM   6936  C CB    . HIS C 1 43  ? 5.962    -104.730 12.967  1.00 37.22  ? 43   HIS C CB    1 
ATOM   6937  C CG    . HIS C 1 43  ? 6.073    -106.008 13.740  1.00 37.83  ? 43   HIS C CG    1 
ATOM   6938  N ND1   . HIS C 1 43  ? 6.662    -107.136 13.196  1.00 42.93  ? 43   HIS C ND1   1 
ATOM   6939  C CD2   . HIS C 1 43  ? 5.601    -106.371 14.957  1.00 38.95  ? 43   HIS C CD2   1 
ATOM   6940  C CE1   . HIS C 1 43  ? 6.559    -108.149 14.062  1.00 51.07  ? 43   HIS C CE1   1 
ATOM   6941  N NE2   . HIS C 1 43  ? 5.899    -107.716 15.142  1.00 49.90  ? 43   HIS C NE2   1 
ATOM   6942  N N     . ASP C 1 44  ? 2.877    -104.143 13.845  1.00 35.43  ? 44   ASP C N     1 
ATOM   6943  C CA    . ASP C 1 44  ? 1.776    -104.460 14.744  1.00 38.32  ? 44   ASP C CA    1 
ATOM   6944  C C     . ASP C 1 44  ? 0.487    -104.637 13.949  1.00 38.54  ? 44   ASP C C     1 
ATOM   6945  O O     . ASP C 1 44  ? -0.225   -105.605 14.174  1.00 35.17  ? 44   ASP C O     1 
ATOM   6946  C CB    . ASP C 1 44  ? 1.657    -103.452 15.872  1.00 47.17  ? 44   ASP C CB    1 
ATOM   6947  C CG    . ASP C 1 44  ? 2.848    -103.424 16.824  1.00 54.39  ? 44   ASP C CG    1 
ATOM   6948  O OD1   . ASP C 1 44  ? 3.607    -104.429 16.845  1.00 53.07  ? 44   ASP C OD1   1 
ATOM   6949  O OD2   . ASP C 1 44  ? 3.021    -102.395 17.517  1.00 55.41  ? 44   ASP C OD2   1 
ATOM   6950  N N     . TYR C 1 45  ? 0.234    -103.740 12.981  1.00 32.83  ? 45   TYR C N     1 
ATOM   6951  C CA    . TYR C 1 45  ? -0.928   -103.843 12.121  1.00 30.74  ? 45   TYR C CA    1 
ATOM   6952  C C     . TYR C 1 45  ? -0.928   -105.173 11.367  1.00 33.35  ? 45   TYR C C     1 
ATOM   6953  O O     . TYR C 1 45  ? -1.953   -105.865 11.368  1.00 34.09  ? 45   TYR C O     1 
ATOM   6954  C CB    . TYR C 1 45  ? -0.999   -102.620 11.210  1.00 31.35  ? 45   TYR C CB    1 
ATOM   6955  C CG    . TYR C 1 45  ? -2.186   -102.691 10.249  1.00 36.03  ? 45   TYR C CG    1 
ATOM   6956  C CD1   . TYR C 1 45  ? -3.462   -102.264 10.629  1.00 34.44  ? 45   TYR C CD1   1 
ATOM   6957  C CD2   . TYR C 1 45  ? -2.029   -103.199 8.966   1.00 31.02  ? 45   TYR C CD2   1 
ATOM   6958  C CE1   . TYR C 1 45  ? -4.538   -102.318 9.751   1.00 30.40  ? 45   TYR C CE1   1 
ATOM   6959  C CE2   . TYR C 1 45  ? -3.089   -103.250 8.084   1.00 31.35  ? 45   TYR C CE2   1 
ATOM   6960  C CZ    . TYR C 1 45  ? -4.345   -102.815 8.475   1.00 34.25  ? 45   TYR C CZ    1 
ATOM   6961  O OH    . TYR C 1 45  ? -5.374   -102.876 7.586   1.00 28.90  ? 45   TYR C OH    1 
ATOM   6962  N N     . GLU C 1 46  ? 0.228    -105.562 10.796  1.00 32.43  ? 46   GLU C N     1 
ATOM   6963  C CA    . GLU C 1 46  ? 0.309    -106.764 9.976   1.00 30.49  ? 46   GLU C CA    1 
ATOM   6964  C C     . GLU C 1 46  ? 0.097    -108.044 10.783  1.00 29.37  ? 46   GLU C C     1 
ATOM   6965  O O     . GLU C 1 46  ? -0.209   -109.087 10.199  1.00 34.57  ? 46   GLU C O     1 
ATOM   6966  C CB    . GLU C 1 46  ? 1.538    -106.755 9.069   1.00 31.18  ? 46   GLU C CB    1 
ATOM   6967  C CG    . GLU C 1 46  ? 1.494    -105.590 8.093   1.00 36.25  ? 46   GLU C CG    1 
ATOM   6968  C CD    . GLU C 1 46  ? 2.591    -105.636 7.046   1.00 44.09  ? 46   GLU C CD    1 
ATOM   6969  O OE1   . GLU C 1 46  ? 3.512    -106.449 7.225   1.00 50.61  ? 46   GLU C OE1   1 
ATOM   6970  O OE2   . GLU C 1 46  ? 2.556    -104.876 6.050   1.00 44.35  ? 46   GLU C OE2   1 
ATOM   6971  N N     . GLN C 1 47  ? 0.194    -107.959 12.115  1.00 28.06  ? 47   GLN C N     1 
ATOM   6972  C CA    . GLN C 1 47  ? -0.121   -109.102 12.974  1.00 34.96  ? 47   GLN C CA    1 
ATOM   6973  C C     . GLN C 1 47  ? -1.592   -109.521 12.858  1.00 35.33  ? 47   GLN C C     1 
ATOM   6974  O O     . GLN C 1 47  ? -1.940   -110.628 13.276  1.00 38.18  ? 47   GLN C O     1 
ATOM   6975  C CB    . GLN C 1 47  ? 0.162    -108.806 14.453  1.00 39.54  ? 47   GLN C CB    1 
ATOM   6976  C CG    . GLN C 1 47  ? 1.641    -108.620 14.795  1.00 49.71  ? 47   GLN C CG    1 
ATOM   6977  C CD    . GLN C 1 47  ? 2.452    -109.871 14.555  1.00 52.29  ? 47   GLN C CD    1 
ATOM   6978  O OE1   . GLN C 1 47  ? 2.311    -110.881 15.259  1.00 56.26  ? 47   GLN C OE1   1 
ATOM   6979  N NE2   . GLN C 1 47  ? 3.264    -109.837 13.511  1.00 52.15  ? 47   GLN C NE2   1 
ATOM   6980  N N     . LEU C 1 48  ? -2.457   -108.633 12.322  1.00 30.48  ? 48   LEU C N     1 
ATOM   6981  C CA    . LEU C 1 48  ? -3.868   -108.949 12.133  1.00 28.67  ? 48   LEU C CA    1 
ATOM   6982  C C     . LEU C 1 48  ? -4.039   -110.188 11.250  1.00 30.94  ? 48   LEU C C     1 
ATOM   6983  O O     . LEU C 1 48  ? -5.096   -110.826 11.301  1.00 29.11  ? 48   LEU C O     1 
ATOM   6984  C CB    . LEU C 1 48  ? -4.641   -107.751 11.568  1.00 27.63  ? 48   LEU C CB    1 
ATOM   6985  C CG    . LEU C 1 48  ? -4.842   -106.580 12.543  1.00 24.40  ? 48   LEU C CG    1 
ATOM   6986  C CD1   . LEU C 1 48  ? -5.429   -105.387 11.791  1.00 20.36  ? 48   LEU C CD1   1 
ATOM   6987  C CD2   . LEU C 1 48  ? -5.749   -107.036 13.674  1.00 21.62  ? 48   LEU C CD2   1 
ATOM   6988  N N     . ILE C 1 49  ? -3.005   -110.544 10.455  1.00 31.47  ? 49   ILE C N     1 
ATOM   6989  C CA    . ILE C 1 49  ? -3.062   -111.790 9.690   1.00 31.23  ? 49   ILE C CA    1 
ATOM   6990  C C     . ILE C 1 49  ? -3.327   -112.991 10.609  1.00 31.46  ? 49   ILE C C     1 
ATOM   6991  O O     . ILE C 1 49  ? -3.975   -113.958 10.200  1.00 31.78  ? 49   ILE C O     1 
ATOM   6992  C CB    . ILE C 1 49  ? -1.824   -112.004 8.797   1.00 30.85  ? 49   ILE C CB    1 
ATOM   6993  C CG1   . ILE C 1 49  ? -2.056   -113.147 7.788   1.00 32.40  ? 49   ILE C CG1   1 
ATOM   6994  C CG2   . ILE C 1 49  ? -0.553   -112.247 9.623   1.00 24.29  ? 49   ILE C CG2   1 
ATOM   6995  C CD1   . ILE C 1 49  ? -0.995   -113.213 6.699   1.00 30.79  ? 49   ILE C CD1   1 
ATOM   6996  N N     . LYS C 1 50  ? -2.850   -112.929 11.861  1.00 32.01  ? 50   LYS C N     1 
ATOM   6997  C CA    . LYS C 1 50  ? -2.911   -114.092 12.741  1.00 36.09  ? 50   LYS C CA    1 
ATOM   6998  C C     . LYS C 1 50  ? -4.330   -114.356 13.218  1.00 37.27  ? 50   LYS C C     1 
ATOM   6999  O O     . LYS C 1 50  ? -4.616   -115.466 13.648  1.00 39.60  ? 50   LYS C O     1 
ATOM   7000  C CB    . LYS C 1 50  ? -1.966   -113.971 13.941  1.00 35.69  ? 50   LYS C CB    1 
ATOM   7001  C CG    . LYS C 1 50  ? -0.533   -114.092 13.472  1.00 46.38  ? 50   LYS C CG    1 
ATOM   7002  C CD    . LYS C 1 50  ? 0.484    -113.758 14.545  1.00 59.76  ? 50   LYS C CD    1 
ATOM   7003  C CE    . LYS C 1 50  ? 1.788    -114.108 13.902  1.00 67.20  ? 50   LYS C CE    1 
ATOM   7004  N NZ    . LYS C 1 50  ? 2.909    -113.802 14.793  1.00 64.12  ? 50   LYS C NZ    1 
ATOM   7005  N N     . THR C 1 51  ? -5.200   -113.335 13.156  1.00 32.48  ? 51   THR C N     1 
ATOM   7006  C CA    . THR C 1 51  ? -6.573   -113.501 13.611  1.00 32.22  ? 51   THR C CA    1 
ATOM   7007  C C     . THR C 1 51  ? -7.540   -113.438 12.424  1.00 33.57  ? 51   THR C C     1 
ATOM   7008  O O     . THR C 1 51  ? -8.741   -113.313 12.623  1.00 36.90  ? 51   THR C O     1 
ATOM   7009  C CB    . THR C 1 51  ? -6.901   -112.498 14.722  1.00 31.31  ? 51   THR C CB    1 
ATOM   7010  O OG1   . THR C 1 51  ? -6.320   -111.264 14.276  1.00 31.64  ? 51   THR C OG1   1 
ATOM   7011  C CG2   . THR C 1 51  ? -6.307   -112.913 16.056  1.00 29.54  ? 51   THR C CG2   1 
ATOM   7012  N N     . PHE C 1 52  ? -7.023   -113.517 11.193  1.00 33.88  ? 52   PHE C N     1 
ATOM   7013  C CA    . PHE C 1 52  ? -7.869   -113.551 10.014  1.00 29.96  ? 52   PHE C CA    1 
ATOM   7014  C C     . PHE C 1 52  ? -8.355   -114.979 9.773   1.00 28.55  ? 52   PHE C C     1 
ATOM   7015  O O     . PHE C 1 52  ? -7.745   -115.720 8.995   1.00 32.94  ? 52   PHE C O     1 
ATOM   7016  C CB    . PHE C 1 52  ? -7.109   -113.010 8.795   1.00 28.45  ? 52   PHE C CB    1 
ATOM   7017  C CG    . PHE C 1 52  ? -7.977   -112.821 7.548   1.00 30.05  ? 52   PHE C CG    1 
ATOM   7018  C CD1   . PHE C 1 52  ? -8.807   -111.699 7.399   1.00 30.58  ? 52   PHE C CD1   1 
ATOM   7019  C CD2   . PHE C 1 52  ? -7.940   -113.747 6.512   1.00 28.64  ? 52   PHE C CD2   1 
ATOM   7020  C CE1   . PHE C 1 52  ? -9.579   -111.515 6.254   1.00 32.25  ? 52   PHE C CE1   1 
ATOM   7021  C CE2   . PHE C 1 52  ? -8.713   -113.573 5.360   1.00 32.47  ? 52   PHE C CE2   1 
ATOM   7022  C CZ    . PHE C 1 52  ? -9.545   -112.459 5.228   1.00 34.93  ? 52   PHE C CZ    1 
ATOM   7023  N N     . THR C 1 53  ? -9.463   -115.361 10.419  1.00 28.50  ? 53   THR C N     1 
ATOM   7024  C CA    . THR C 1 53  ? -9.977   -116.731 10.355  1.00 29.88  ? 53   THR C CA    1 
ATOM   7025  C C     . THR C 1 53  ? -10.962  -116.896 9.201   1.00 32.04  ? 53   THR C C     1 
ATOM   7026  O O     . THR C 1 53  ? -11.213  -118.017 8.786   1.00 30.25  ? 53   THR C O     1 
ATOM   7027  C CB    . THR C 1 53  ? -10.678  -117.098 11.664  1.00 32.30  ? 53   THR C CB    1 
ATOM   7028  O OG1   . THR C 1 53  ? -11.776  -116.193 11.692  1.00 37.04  ? 53   THR C OG1   1 
ATOM   7029  C CG2   . THR C 1 53  ? -9.820   -116.923 12.911  1.00 24.99  ? 53   THR C CG2   1 
ATOM   7030  N N     . ALA C 1 54  ? -11.582  -115.780 8.749   1.00 28.34  ? 54   ALA C N     1 
ATOM   7031  C CA    . ALA C 1 54  ? -12.667  -115.831 7.781   1.00 24.92  ? 54   ALA C CA    1 
ATOM   7032  C C     . ALA C 1 54  ? -13.788  -116.741 8.261   1.00 25.90  ? 54   ALA C C     1 
ATOM   7033  O O     . ALA C 1 54  ? -14.485  -117.312 7.436   1.00 26.28  ? 54   ALA C O     1 
ATOM   7034  C CB    . ALA C 1 54  ? -12.184  -116.289 6.424   1.00 24.00  ? 54   ALA C CB    1 
ATOM   7035  N N     . ALA C 1 55  ? -13.968  -116.851 9.584   1.00 31.14  ? 55   ALA C N     1 
ATOM   7036  C CA    . ALA C 1 55  ? -14.897  -117.819 10.160  1.00 33.52  ? 55   ALA C CA    1 
ATOM   7037  C C     . ALA C 1 55  ? -16.342  -117.578 9.706   1.00 38.88  ? 55   ALA C C     1 
ATOM   7038  O O     . ALA C 1 55  ? -17.162  -118.485 9.763   1.00 37.09  ? 55   ALA C O     1 
ATOM   7039  C CB    . ALA C 1 55  ? -14.783  -117.824 11.687  1.00 28.33  ? 55   ALA C CB    1 
ATOM   7040  N N     . GLN C 1 56  ? -16.698  -116.361 9.280   1.00 40.99  ? 56   GLN C N     1 
ATOM   7041  C CA    . GLN C 1 56  ? -18.090  -116.132 8.919   1.00 36.78  ? 56   GLN C CA    1 
ATOM   7042  C C     . GLN C 1 56  ? -18.235  -115.756 7.457   1.00 34.13  ? 56   GLN C C     1 
ATOM   7043  O O     . GLN C 1 56  ? -19.278  -115.269 7.048   1.00 33.85  ? 56   GLN C O     1 
ATOM   7044  C CB    . GLN C 1 56  ? -18.747  -115.095 9.815   1.00 37.64  ? 56   GLN C CB    1 
ATOM   7045  C CG    . GLN C 1 56  ? -19.279  -115.699 11.108  1.00 44.22  ? 56   GLN C CG    1 
ATOM   7046  C CD    . GLN C 1 56  ? -18.957  -114.790 12.258  1.00 59.05  ? 56   GLN C CD    1 
ATOM   7047  O OE1   . GLN C 1 56  ? -19.683  -113.843 12.569  1.00 55.63  ? 56   GLN C OE1   1 
ATOM   7048  N NE2   . GLN C 1 56  ? -17.785  -115.022 12.828  1.00 80.32  ? 56   GLN C NE2   1 
ATOM   7049  N N     . PHE C 1 57  ? -17.189  -115.997 6.664   1.00 33.24  ? 57   PHE C N     1 
ATOM   7050  C CA    . PHE C 1 57  ? -17.303  -115.688 5.257   1.00 30.40  ? 57   PHE C CA    1 
ATOM   7051  C C     . PHE C 1 57  ? -18.019  -116.836 4.564   1.00 33.79  ? 57   PHE C C     1 
ATOM   7052  O O     . PHE C 1 57  ? -17.538  -117.959 4.571   1.00 39.40  ? 57   PHE C O     1 
ATOM   7053  C CB    . PHE C 1 57  ? -15.923  -115.468 4.654   1.00 25.50  ? 57   PHE C CB    1 
ATOM   7054  C CG    . PHE C 1 57  ? -15.972  -115.174 3.162   1.00 26.47  ? 57   PHE C CG    1 
ATOM   7055  C CD1   . PHE C 1 57  ? -16.415  -113.932 2.681   1.00 25.29  ? 57   PHE C CD1   1 
ATOM   7056  C CD2   . PHE C 1 57  ? -15.541  -116.125 2.251   1.00 22.55  ? 57   PHE C CD2   1 
ATOM   7057  C CE1   . PHE C 1 57  ? -16.413  -113.645 1.324   1.00 24.44  ? 57   PHE C CE1   1 
ATOM   7058  C CE2   . PHE C 1 57  ? -15.534  -115.838 0.891   1.00 23.47  ? 57   PHE C CE2   1 
ATOM   7059  C CZ    . PHE C 1 57  ? -15.961  -114.598 0.425   1.00 28.30  ? 57   PHE C CZ    1 
ATOM   7060  N N     . ASP C 1 58  ? -19.149  -116.530 3.935   1.00 36.96  ? 58   ASP C N     1 
ATOM   7061  C CA    . ASP C 1 58  ? -19.849  -117.518 3.141   1.00 33.69  ? 58   ASP C CA    1 
ATOM   7062  C C     . ASP C 1 58  ? -20.128  -116.926 1.756   1.00 34.46  ? 58   ASP C C     1 
ATOM   7063  O O     . ASP C 1 58  ? -21.058  -116.131 1.568   1.00 30.57  ? 58   ASP C O     1 
ATOM   7064  C CB    . ASP C 1 58  ? -21.105  -117.943 3.880   1.00 37.37  ? 58   ASP C CB    1 
ATOM   7065  C CG    . ASP C 1 58  ? -21.952  -119.025 3.222   1.00 41.18  ? 58   ASP C CG    1 
ATOM   7066  O OD1   . ASP C 1 58  ? -21.652  -119.405 2.055   1.00 38.59  ? 58   ASP C OD1   1 
ATOM   7067  O OD2   . ASP C 1 58  ? -22.892  -119.500 3.889   1.00 54.33  ? 58   ASP C OD2   1 
ATOM   7068  N N     . ALA C 1 59  ? -19.323  -117.340 0.774   1.00 32.07  ? 59   ALA C N     1 
ATOM   7069  C CA    . ALA C 1 59  ? -19.395  -116.750 -0.549  1.00 30.04  ? 59   ALA C CA    1 
ATOM   7070  C C     . ALA C 1 59  ? -20.778  -117.015 -1.158  1.00 33.44  ? 59   ALA C C     1 
ATOM   7071  O O     . ALA C 1 59  ? -21.262  -116.224 -1.960  1.00 33.75  ? 59   ALA C O     1 
ATOM   7072  C CB    . ALA C 1 59  ? -18.266  -117.302 -1.423  1.00 25.21  ? 59   ALA C CB    1 
ATOM   7073  N N     . LYS C 1 60  ? -21.404  -118.141 -0.796  1.00 34.14  ? 60   LYS C N     1 
ATOM   7074  C CA    . LYS C 1 60  ? -22.703  -118.502 -1.347  1.00 37.67  ? 60   LYS C CA    1 
ATOM   7075  C C     . LYS C 1 60  ? -23.752  -117.507 -0.851  1.00 37.66  ? 60   LYS C C     1 
ATOM   7076  O O     . LYS C 1 60  ? -24.587  -117.068 -1.637  1.00 34.94  ? 60   LYS C O     1 
ATOM   7077  C CB    . LYS C 1 60  ? -23.161  -119.937 -1.054  1.00 42.71  ? 60   LYS C CB    1 
ATOM   7078  C CG    . LYS C 1 60  ? -22.382  -120.969 -1.842  1.00 59.26  ? 60   LYS C CG    1 
ATOM   7079  C CD    . LYS C 1 60  ? -22.412  -122.424 -1.383  1.00 75.47  ? 60   LYS C CD    1 
ATOM   7080  C CE    . LYS C 1 60  ? -21.556  -123.191 -2.367  1.00 81.45  ? 60   LYS C CE    1 
ATOM   7081  N NZ    . LYS C 1 60  ? -21.330  -124.592 -2.013  1.00 73.17  ? 60   LYS C NZ    1 
ATOM   7082  N N     . LYS C 1 61  ? -23.690  -117.138 0.441   1.00 32.27  ? 61   LYS C N     1 
ATOM   7083  C CA    . LYS C 1 61  ? -24.612  -116.162 0.992   1.00 36.03  ? 61   LYS C CA    1 
ATOM   7084  C C     . LYS C 1 61  ? -24.424  -114.807 0.298   1.00 40.10  ? 61   LYS C C     1 
ATOM   7085  O O     . LYS C 1 61  ? -25.399  -114.132 -0.030  1.00 36.21  ? 61   LYS C O     1 
ATOM   7086  C CB    . LYS C 1 61  ? -24.552  -116.065 2.518   1.00 43.58  ? 61   LYS C CB    1 
ATOM   7087  C CG    . LYS C 1 61  ? -25.387  -117.156 3.204   1.00 64.75  ? 61   LYS C CG    1 
ATOM   7088  C CD    . LYS C 1 61  ? -25.716  -116.893 4.677   1.00 80.59  ? 61   LYS C CD    1 
ATOM   7089  C CE    . LYS C 1 61  ? -24.562  -117.038 5.651   1.00 88.51  ? 61   LYS C CE    1 
ATOM   7090  N NZ    . LYS C 1 61  ? -24.627  -118.054 6.717   1.00 76.99  ? 61   LYS C NZ    1 
ATOM   7091  N N     . ILE C 1 62  ? -23.173  -114.428 0.051   1.00 34.23  ? 62   ILE C N     1 
ATOM   7092  C CA    . ILE C 1 62  ? -22.885  -113.155 -0.578  1.00 32.20  ? 62   ILE C CA    1 
ATOM   7093  C C     . ILE C 1 62  ? -23.428  -113.140 -2.001  1.00 33.04  ? 62   ILE C C     1 
ATOM   7094  O O     . ILE C 1 62  ? -24.088  -112.181 -2.400  1.00 37.76  ? 62   ILE C O     1 
ATOM   7095  C CB    . ILE C 1 62  ? -21.384  -112.837 -0.484  1.00 30.33  ? 62   ILE C CB    1 
ATOM   7096  C CG1   . ILE C 1 62  ? -21.034  -112.536 0.958   1.00 30.84  ? 62   ILE C CG1   1 
ATOM   7097  C CG2   . ILE C 1 62  ? -21.021  -111.684 -1.403  1.00 27.31  ? 62   ILE C CG2   1 
ATOM   7098  C CD1   . ILE C 1 62  ? -19.549  -112.456 1.227   1.00 32.24  ? 62   ILE C CD1   1 
ATOM   7099  N N     . ALA C 1 63  ? -23.199  -114.219 -2.748  1.00 30.68  ? 63   ALA C N     1 
ATOM   7100  C CA    . ALA C 1 63  ? -23.702  -114.287 -4.111  1.00 29.53  ? 63   ALA C CA    1 
ATOM   7101  C C     . ALA C 1 63  ? -25.236  -114.249 -4.138  1.00 29.55  ? 63   ALA C C     1 
ATOM   7102  O O     . ALA C 1 63  ? -25.825  -113.560 -4.969  1.00 28.10  ? 63   ALA C O     1 
ATOM   7103  C CB    . ALA C 1 63  ? -23.134  -115.492 -4.829  1.00 25.57  ? 63   ALA C CB    1 
ATOM   7104  N N     . HIS C 1 64  ? -25.872  -114.968 -3.212  1.00 30.31  ? 64   HIS C N     1 
ATOM   7105  C CA    . HIS C 1 64  ? -27.327  -114.980 -3.096  1.00 35.51  ? 64   HIS C CA    1 
ATOM   7106  C C     . HIS C 1 64  ? -27.850  -113.562 -2.839  1.00 34.08  ? 64   HIS C C     1 
ATOM   7107  O O     . HIS C 1 64  ? -28.778  -113.101 -3.490  1.00 33.63  ? 64   HIS C O     1 
ATOM   7108  C CB    . HIS C 1 64  ? -27.815  -116.042 -2.086  1.00 40.41  ? 64   HIS C CB    1 
ATOM   7109  C CG    . HIS C 1 64  ? -29.309  -116.202 -2.121  1.00 68.63  ? 64   HIS C CG    1 
ATOM   7110  N ND1   . HIS C 1 64  ? -30.160  -115.417 -1.356  1.00 70.07  ? 64   HIS C ND1   1 
ATOM   7111  C CD2   . HIS C 1 64  ? -30.115  -117.032 -2.852  1.00 67.25  ? 64   HIS C CD2   1 
ATOM   7112  C CE1   . HIS C 1 64  ? -31.422  -115.743 -1.614  1.00 66.95  ? 64   HIS C CE1   1 
ATOM   7113  N NE2   . HIS C 1 64  ? -31.411  -116.720 -2.517  1.00 71.63  ? 64   HIS C NE2   1 
ATOM   7114  N N     . ALA C 1 65  ? -27.240  -112.863 -1.882  1.00 35.80  ? 65   ALA C N     1 
ATOM   7115  C CA    . ALA C 1 65  ? -27.654  -111.511 -1.548  1.00 31.20  ? 65   ALA C CA    1 
ATOM   7116  C C     . ALA C 1 65  ? -27.492  -110.588 -2.763  1.00 33.55  ? 65   ALA C C     1 
ATOM   7117  O O     . ALA C 1 65  ? -28.378  -109.778 -3.039  1.00 33.60  ? 65   ALA C O     1 
ATOM   7118  C CB    . ALA C 1 65  ? -26.905  -111.023 -0.331  1.00 29.10  ? 65   ALA C CB    1 
ATOM   7119  N N     . ALA C 1 66  ? -26.393  -110.723 -3.517  1.00 28.35  ? 66   ALA C N     1 
ATOM   7120  C CA    . ALA C 1 66  ? -26.209  -109.919 -4.713  1.00 26.36  ? 66   ALA C CA    1 
ATOM   7121  C C     . ALA C 1 66  ? -27.326  -110.193 -5.735  1.00 29.65  ? 66   ALA C C     1 
ATOM   7122  O O     . ALA C 1 66  ? -27.866  -109.263 -6.354  1.00 27.83  ? 66   ALA C O     1 
ATOM   7123  C CB    . ALA C 1 66  ? -24.845  -110.187 -5.305  1.00 24.28  ? 66   ALA C CB    1 
ATOM   7124  N N     . LYS C 1 67  ? -27.683  -111.473 -5.915  1.00 27.36  ? 67   LYS C N     1 
ATOM   7125  C CA    . LYS C 1 67  ? -28.734  -111.839 -6.847  1.00 34.77  ? 67   LYS C CA    1 
ATOM   7126  C C     . LYS C 1 67  ? -30.064  -111.222 -6.392  1.00 33.73  ? 67   LYS C C     1 
ATOM   7127  O O     . LYS C 1 67  ? -30.749  -110.629 -7.205  1.00 35.12  ? 67   LYS C O     1 
ATOM   7128  C CB    . LYS C 1 67  ? -28.850  -113.361 -7.028  1.00 40.66  ? 67   LYS C CB    1 
ATOM   7129  C CG    . LYS C 1 67  ? -29.900  -113.840 -8.027  1.00 45.74  ? 67   LYS C CG    1 
ATOM   7130  C CD    . LYS C 1 67  ? -29.178  -114.145 -9.328  1.00 60.41  ? 67   LYS C CD    1 
ATOM   7131  C CE    . LYS C 1 67  ? -29.986  -114.884 -10.337 1.00 63.88  ? 67   LYS C CE    1 
ATOM   7132  N NZ    . LYS C 1 67  ? -29.198  -114.778 -11.567 1.00 65.56  ? 67   LYS C NZ    1 
ATOM   7133  N N     . ALA C 1 68  ? -30.398  -111.328 -5.095  1.00 28.74  ? 68   ALA C N     1 
ATOM   7134  C CA    . ALA C 1 68  ? -31.645  -110.823 -4.541  1.00 29.80  ? 68   ALA C CA    1 
ATOM   7135  C C     . ALA C 1 68  ? -31.743  -109.305 -4.713  1.00 32.03  ? 68   ALA C C     1 
ATOM   7136  O O     . ALA C 1 68  ? -32.831  -108.771 -4.882  1.00 35.10  ? 68   ALA C O     1 
ATOM   7137  C CB    . ALA C 1 68  ? -31.784  -111.217 -3.066  1.00 23.87  ? 68   ALA C CB    1 
ATOM   7138  N N     . VAL C 1 69  ? -30.612  -108.597 -4.652  1.00 27.56  ? 69   VAL C N     1 
ATOM   7139  C CA    . VAL C 1 69  ? -30.663  -107.146 -4.706  1.00 28.56  ? 69   VAL C CA    1 
ATOM   7140  C C     . VAL C 1 69  ? -30.750  -106.708 -6.177  1.00 26.85  ? 69   VAL C C     1 
ATOM   7141  O O     . VAL C 1 69  ? -30.873  -105.514 -6.450  1.00 31.40  ? 69   VAL C O     1 
ATOM   7142  C CB    . VAL C 1 69  ? -29.470  -106.501 -3.956  1.00 25.86  ? 69   VAL C CB    1 
ATOM   7143  C CG1   . VAL C 1 69  ? -28.207  -106.465 -4.811  1.00 24.91  ? 69   VAL C CG1   1 
ATOM   7144  C CG2   . VAL C 1 69  ? -29.774  -105.073 -3.568  1.00 35.31  ? 69   VAL C CG2   1 
ATOM   7145  N N     . GLY C 1 70  ? -30.669  -107.665 -7.117  1.00 23.01  ? 70   GLY C N     1 
ATOM   7146  C CA    . GLY C 1 70  ? -30.693  -107.357 -8.547  1.00 23.57  ? 70   GLY C CA    1 
ATOM   7147  C C     . GLY C 1 70  ? -29.330  -106.983 -9.160  1.00 26.96  ? 70   GLY C C     1 
ATOM   7148  O O     . GLY C 1 70  ? -29.274  -106.481 -10.289 1.00 23.98  ? 70   GLY C O     1 
ATOM   7149  N N     . ALA C 1 71  ? -28.223  -107.229 -8.434  1.00 25.81  ? 71   ALA C N     1 
ATOM   7150  C CA    . ALA C 1 71  ? -26.888  -107.026 -8.989  1.00 25.90  ? 71   ALA C CA    1 
ATOM   7151  C C     . ALA C 1 71  ? -26.556  -108.140 -9.994  1.00 25.62  ? 71   ALA C C     1 
ATOM   7152  O O     . ALA C 1 71  ? -27.015  -109.260 -9.849  1.00 24.86  ? 71   ALA C O     1 
ATOM   7153  C CB    . ALA C 1 71  ? -25.853  -106.957 -7.865  1.00 22.24  ? 71   ALA C CB    1 
ATOM   7154  N N     . LYS C 1 72  ? -25.743  -107.829 -10.999 1.00 26.70  ? 72   LYS C N     1 
ATOM   7155  C CA    . LYS C 1 72  ? -25.362  -108.800 -12.021 1.00 26.34  ? 72   LYS C CA    1 
ATOM   7156  C C     . LYS C 1 72  ? -23.859  -109.097 -11.964 1.00 27.11  ? 72   LYS C C     1 
ATOM   7157  O O     . LYS C 1 72  ? -23.364  -109.946 -12.702 1.00 28.43  ? 72   LYS C O     1 
ATOM   7158  C CB    . LYS C 1 72  ? -25.766  -108.278 -13.411 1.00 29.49  ? 72   LYS C CB    1 
ATOM   7159  C CG    . LYS C 1 72  ? -27.290  -108.178 -13.634 1.00 32.65  ? 72   LYS C CG    1 
ATOM   7160  C CD    . LYS C 1 72  ? -27.972  -109.542 -13.493 1.00 30.85  ? 72   LYS C CD    1 
ATOM   7161  C CE    . LYS C 1 72  ? -29.478  -109.546 -13.703 1.00 41.31  ? 72   LYS C CE    1 
ATOM   7162  N NZ    . LYS C 1 72  ? -29.818  -109.086 -15.065 1.00 43.69  ? 72   LYS C NZ    1 
ATOM   7163  N N     . TYR C 1 73  ? -23.126  -108.387 -11.091 1.00 27.75  ? 73   TYR C N     1 
ATOM   7164  C CA    . TYR C 1 73  ? -21.706  -108.643 -10.884 1.00 25.68  ? 73   TYR C CA    1 
ATOM   7165  C C     . TYR C 1 73  ? -21.318  -108.201 -9.483  1.00 25.98  ? 73   TYR C C     1 
ATOM   7166  O O     . TYR C 1 73  ? -22.081  -107.444 -8.849  1.00 23.99  ? 73   TYR C O     1 
ATOM   7167  C CB    . TYR C 1 73  ? -20.833  -107.962 -11.940 1.00 24.29  ? 73   TYR C CB    1 
ATOM   7168  C CG    . TYR C 1 73  ? -20.827  -106.443 -12.042 1.00 24.29  ? 73   TYR C CG    1 
ATOM   7169  C CD1   . TYR C 1 73  ? -21.976  -105.717 -12.367 1.00 23.17  ? 73   TYR C CD1   1 
ATOM   7170  C CD2   . TYR C 1 73  ? -19.634  -105.732 -11.889 1.00 24.19  ? 73   TYR C CD2   1 
ATOM   7171  C CE1   . TYR C 1 73  ? -21.934  -104.339 -12.537 1.00 20.04  ? 73   TYR C CE1   1 
ATOM   7172  C CE2   . TYR C 1 73  ? -19.576  -104.353 -12.044 1.00 24.30  ? 73   TYR C CE2   1 
ATOM   7173  C CZ    . TYR C 1 73  ? -20.731  -103.661 -12.386 1.00 24.96  ? 73   TYR C CZ    1 
ATOM   7174  O OH    . TYR C 1 73  ? -20.638  -102.302 -12.571 1.00 26.47  ? 73   TYR C OH    1 
ATOM   7175  N N     . ILE C 1 74  ? -20.163  -108.703 -9.012  1.00 22.58  ? 74   ILE C N     1 
ATOM   7176  C CA    . ILE C 1 74  ? -19.632  -108.359 -7.703  1.00 21.19  ? 74   ILE C CA    1 
ATOM   7177  C C     . ILE C 1 74  ? -18.154  -108.024 -7.877  1.00 25.08  ? 74   ILE C C     1 
ATOM   7178  O O     . ILE C 1 74  ? -17.408  -108.785 -8.520  1.00 22.27  ? 74   ILE C O     1 
ATOM   7179  C CB    . ILE C 1 74  ? -19.792  -109.513 -6.699  1.00 21.65  ? 74   ILE C CB    1 
ATOM   7180  C CG1   . ILE C 1 74  ? -21.218  -110.026 -6.615  1.00 18.87  ? 74   ILE C CG1   1 
ATOM   7181  C CG2   . ILE C 1 74  ? -19.254  -109.098 -5.332  1.00 21.46  ? 74   ILE C CG2   1 
ATOM   7182  C CD1   . ILE C 1 74  ? -21.365  -111.246 -5.717  1.00 17.48  ? 74   ILE C CD1   1 
ATOM   7183  N N     . VAL C 1 75  ? -17.753  -106.864 -7.330  1.00 24.23  ? 75   VAL C N     1 
ATOM   7184  C CA    . VAL C 1 75  ? -16.346  -106.511 -7.251  1.00 22.47  ? 75   VAL C CA    1 
ATOM   7185  C C     . VAL C 1 75  ? -15.865  -106.755 -5.819  1.00 23.34  ? 75   VAL C C     1 
ATOM   7186  O O     . VAL C 1 75  ? -16.354  -106.105 -4.888  1.00 22.92  ? 75   VAL C O     1 
ATOM   7187  C CB    . VAL C 1 75  ? -16.174  -105.039 -7.645  1.00 20.90  ? 75   VAL C CB    1 
ATOM   7188  C CG1   . VAL C 1 75  ? -14.709  -104.624 -7.621  1.00 19.52  ? 75   VAL C CG1   1 
ATOM   7189  C CG2   . VAL C 1 75  ? -16.782  -104.766 -9.013  1.00 17.12  ? 75   VAL C CG2   1 
ATOM   7190  N N     . LEU C 1 76  ? -14.942  -107.714 -5.651  1.00 22.63  ? 76   LEU C N     1 
ATOM   7191  C CA    . LEU C 1 76  ? -14.360  -108.045 -4.351  1.00 23.12  ? 76   LEU C CA    1 
ATOM   7192  C C     . LEU C 1 76  ? -12.925  -107.521 -4.258  1.00 24.01  ? 76   LEU C C     1 
ATOM   7193  O O     . LEU C 1 76  ? -12.139  -107.669 -5.206  1.00 23.93  ? 76   LEU C O     1 
ATOM   7194  C CB    . LEU C 1 76  ? -14.408  -109.558 -4.130  1.00 22.59  ? 76   LEU C CB    1 
ATOM   7195  C CG    . LEU C 1 76  ? -13.805  -110.070 -2.821  1.00 24.55  ? 76   LEU C CG    1 
ATOM   7196  C CD1   . LEU C 1 76  ? -14.481  -109.474 -1.598  1.00 22.76  ? 76   LEU C CD1   1 
ATOM   7197  C CD2   . LEU C 1 76  ? -13.888  -111.588 -2.765  1.00 23.16  ? 76   LEU C CD2   1 
ATOM   7198  N N     . THR C 1 77  ? -12.597  -106.873 -3.128  1.00 22.88  ? 77   THR C N     1 
ATOM   7199  C CA    . THR C 1 77  ? -11.223  -106.453 -2.876  1.00 23.57  ? 77   THR C CA    1 
ATOM   7200  C C     . THR C 1 77  ? -10.314  -107.688 -2.738  1.00 26.11  ? 77   THR C C     1 
ATOM   7201  O O     . THR C 1 77  ? -10.387  -108.402 -1.729  1.00 30.46  ? 77   THR C O     1 
ATOM   7202  C CB    . THR C 1 77  ? -11.154  -105.589 -1.616  1.00 22.76  ? 77   THR C CB    1 
ATOM   7203  O OG1   . THR C 1 77  ? -11.774  -106.288 -0.535  1.00 24.00  ? 77   THR C OG1   1 
ATOM   7204  C CG2   . THR C 1 77  ? -11.796  -104.227 -1.789  1.00 25.14  ? 77   THR C CG2   1 
ATOM   7205  N N     . THR C 1 78  ? -9.449   -107.947 -3.734  1.00 23.72  ? 78   THR C N     1 
ATOM   7206  C CA    . THR C 1 78  ? -8.570   -109.115 -3.633  1.00 27.35  ? 78   THR C CA    1 
ATOM   7207  C C     . THR C 1 78  ? -7.273   -108.748 -2.911  1.00 29.49  ? 78   THR C C     1 
ATOM   7208  O O     . THR C 1 78  ? -6.609   -109.622 -2.335  1.00 28.08  ? 78   THR C O     1 
ATOM   7209  C CB    . THR C 1 78  ? -8.272   -109.752 -4.994  1.00 29.02  ? 78   THR C CB    1 
ATOM   7210  O OG1   . THR C 1 78  ? -7.447   -108.829 -5.696  1.00 29.19  ? 78   THR C OG1   1 
ATOM   7211  C CG2   . THR C 1 78  ? -9.519   -110.124 -5.769  1.00 24.74  ? 78   THR C CG2   1 
ATOM   7212  N N     . LYS C 1 79  ? -6.918   -107.451 -2.957  1.00 24.98  ? 79   LYS C N     1 
ATOM   7213  C CA    . LYS C 1 79  ? -5.796   -106.875 -2.233  1.00 25.35  ? 79   LYS C CA    1 
ATOM   7214  C C     . LYS C 1 79  ? -6.008   -105.365 -2.190  1.00 26.65  ? 79   LYS C C     1 
ATOM   7215  O O     . LYS C 1 79  ? -6.065   -104.725 -3.262  1.00 25.39  ? 79   LYS C O     1 
ATOM   7216  C CB    . LYS C 1 79  ? -4.464   -107.156 -2.958  1.00 24.73  ? 79   LYS C CB    1 
ATOM   7217  C CG    . LYS C 1 79  ? -3.209   -106.740 -2.167  1.00 24.35  ? 79   LYS C CG    1 
ATOM   7218  C CD    . LYS C 1 79  ? -1.986   -106.293 -2.974  1.00 21.93  ? 79   LYS C CD    1 
ATOM   7219  C CE    . LYS C 1 79  ? -2.183   -104.970 -3.629  1.00 26.43  ? 79   LYS C CE    1 
ATOM   7220  N NZ    . LYS C 1 79  ? -1.024   -104.460 -4.373  1.00 24.73  ? 79   LYS C NZ    1 
ATOM   7221  N N     . HIS C 1 80  ? -6.117   -104.802 -0.966  1.00 26.27  ? 80   HIS C N     1 
ATOM   7222  C CA    . HIS C 1 80  ? -6.315   -103.350 -0.825  1.00 27.02  ? 80   HIS C CA    1 
ATOM   7223  C C     . HIS C 1 80  ? -4.949   -102.676 -0.577  1.00 31.47  ? 80   HIS C C     1 
ATOM   7224  O O     . HIS C 1 80  ? -3.896   -103.320 -0.689  1.00 33.11  ? 80   HIS C O     1 
ATOM   7225  C CB    . HIS C 1 80  ? -7.420   -103.086 0.210   1.00 23.23  ? 80   HIS C CB    1 
ATOM   7226  C CG    . HIS C 1 80  ? -8.117   -101.779 -0.006  1.00 24.89  ? 80   HIS C CG    1 
ATOM   7227  N ND1   . HIS C 1 80  ? -7.689   -100.577 0.525   1.00 23.13  ? 80   HIS C ND1   1 
ATOM   7228  C CD2   . HIS C 1 80  ? -9.216   -101.488 -0.742  1.00 24.06  ? 80   HIS C CD2   1 
ATOM   7229  C CE1   . HIS C 1 80  ? -8.502   -99.609  0.114   1.00 24.27  ? 80   HIS C CE1   1 
ATOM   7230  N NE2   . HIS C 1 80  ? -9.434   -100.143 -0.656  1.00 24.48  ? 80   HIS C NE2   1 
ATOM   7231  N N     . HIS C 1 81  ? -4.932   -101.383 -0.229  1.00 27.95  ? 81   HIS C N     1 
ATOM   7232  C CA    . HIS C 1 81  ? -3.679   -100.685 0.011   1.00 26.65  ? 81   HIS C CA    1 
ATOM   7233  C C     . HIS C 1 81  ? -2.836   -101.399 1.070   1.00 28.38  ? 81   HIS C C     1 
ATOM   7234  O O     . HIS C 1 81  ? -1.613   -101.412 0.974   1.00 32.71  ? 81   HIS C O     1 
ATOM   7235  C CB    . HIS C 1 81  ? -3.918   -99.221  0.413   1.00 26.12  ? 81   HIS C CB    1 
ATOM   7236  C CG    . HIS C 1 81  ? -4.732   -98.467  -0.594  1.00 30.20  ? 81   HIS C CG    1 
ATOM   7237  N ND1   . HIS C 1 81  ? -4.478   -98.512  -1.949  1.00 29.94  ? 81   HIS C ND1   1 
ATOM   7238  C CD2   . HIS C 1 81  ? -5.814   -97.671  -0.458  1.00 30.42  ? 81   HIS C CD2   1 
ATOM   7239  C CE1   . HIS C 1 81  ? -5.360   -97.759  -2.593  1.00 28.28  ? 81   HIS C CE1   1 
ATOM   7240  N NE2   . HIS C 1 81  ? -6.186   -97.243  -1.708  1.00 29.04  ? 81   HIS C NE2   1 
ATOM   7241  N N     . GLU C 1 82  ? -3.463   -101.971 2.094   1.00 26.07  ? 82   GLU C N     1 
ATOM   7242  C CA    . GLU C 1 82  ? -2.710   -102.642 3.145   1.00 25.44  ? 82   GLU C CA    1 
ATOM   7243  C C     . GLU C 1 82  ? -1.828   -103.744 2.546   1.00 24.24  ? 82   GLU C C     1 
ATOM   7244  O O     . GLU C 1 82  ? -0.901   -104.198 3.199   1.00 29.79  ? 82   GLU C O     1 
ATOM   7245  C CB    . GLU C 1 82  ? -3.628   -103.234 4.225   1.00 23.77  ? 82   GLU C CB    1 
ATOM   7246  C CG    . GLU C 1 82  ? -4.655   -104.203 3.639   1.00 24.15  ? 82   GLU C CG    1 
ATOM   7247  C CD    . GLU C 1 82  ? -5.539   -104.984 4.611   1.00 27.64  ? 82   GLU C CD    1 
ATOM   7248  O OE1   . GLU C 1 82  ? -5.648   -104.613 5.817   1.00 24.77  ? 82   GLU C OE1   1 
ATOM   7249  O OE2   . GLU C 1 82  ? -6.134   -106.005 4.137   1.00 24.95  ? 82   GLU C OE2   1 
ATOM   7250  N N     . GLY C 1 83  ? -2.168   -104.261 1.361   1.00 25.44  ? 83   GLY C N     1 
ATOM   7251  C CA    . GLY C 1 83  ? -1.284   -105.144 0.619   1.00 24.48  ? 83   GLY C CA    1 
ATOM   7252  C C     . GLY C 1 83  ? -1.450   -106.632 0.965   1.00 29.40  ? 83   GLY C C     1 
ATOM   7253  O O     . GLY C 1 83  ? -0.664   -107.456 0.496   1.00 30.53  ? 83   GLY C O     1 
ATOM   7254  N N     . PHE C 1 84  ? -2.460   -106.992 1.770   1.00 27.45  ? 84   PHE C N     1 
ATOM   7255  C CA    . PHE C 1 84  ? -2.754   -108.383 2.106   1.00 26.98  ? 84   PHE C CA    1 
ATOM   7256  C C     . PHE C 1 84  ? -3.633   -109.033 1.033   1.00 30.65  ? 84   PHE C C     1 
ATOM   7257  O O     . PHE C 1 84  ? -4.649   -108.465 0.620   1.00 30.28  ? 84   PHE C O     1 
ATOM   7258  C CB    . PHE C 1 84  ? -3.457   -108.391 3.455   1.00 25.51  ? 84   PHE C CB    1 
ATOM   7259  C CG    . PHE C 1 84  ? -4.043   -109.742 3.820   1.00 27.24  ? 84   PHE C CG    1 
ATOM   7260  C CD1   . PHE C 1 84  ? -3.208   -110.775 4.244   1.00 30.79  ? 84   PHE C CD1   1 
ATOM   7261  C CD2   . PHE C 1 84  ? -5.417   -109.976 3.759   1.00 24.62  ? 84   PHE C CD2   1 
ATOM   7262  C CE1   . PHE C 1 84  ? -3.743   -112.022 4.600   1.00 31.26  ? 84   PHE C CE1   1 
ATOM   7263  C CE2   . PHE C 1 84  ? -5.958   -111.211 4.112   1.00 26.18  ? 84   PHE C CE2   1 
ATOM   7264  C CZ    . PHE C 1 84  ? -5.118   -112.246 4.515   1.00 27.15  ? 84   PHE C CZ    1 
ATOM   7265  N N     . PHE C 1 85  ? -3.265   -110.249 0.602   1.00 29.80  ? 85   PHE C N     1 
ATOM   7266  C CA    . PHE C 1 85  ? -3.960   -110.886 -0.510  1.00 28.04  ? 85   PHE C CA    1 
ATOM   7267  C C     . PHE C 1 85  ? -4.969   -111.913 0.002   1.00 31.56  ? 85   PHE C C     1 
ATOM   7268  O O     . PHE C 1 85  ? -4.635   -112.775 0.824   1.00 32.64  ? 85   PHE C O     1 
ATOM   7269  C CB    . PHE C 1 85  ? -2.966   -111.613 -1.413  1.00 23.07  ? 85   PHE C CB    1 
ATOM   7270  C CG    . PHE C 1 85  ? -1.869   -110.774 -2.047  1.00 22.85  ? 85   PHE C CG    1 
ATOM   7271  C CD1   . PHE C 1 85  ? -0.671   -110.528 -1.365  1.00 22.58  ? 85   PHE C CD1   1 
ATOM   7272  C CD2   . PHE C 1 85  ? -2.021   -110.277 -3.344  1.00 19.72  ? 85   PHE C CD2   1 
ATOM   7273  C CE1   . PHE C 1 85  ? 0.323    -109.755 -1.961  1.00 22.58  ? 85   PHE C CE1   1 
ATOM   7274  C CE2   . PHE C 1 85  ? -1.032   -109.513 -3.935  1.00 21.97  ? 85   PHE C CE2   1 
ATOM   7275  C CZ    . PHE C 1 85  ? 0.154    -109.248 -3.253  1.00 22.29  ? 85   PHE C CZ    1 
ATOM   7276  N N     . LEU C 1 86  ? -6.189   -111.858 -0.552  1.00 31.30  ? 86   LEU C N     1 
ATOM   7277  C CA    . LEU C 1 86  ? -7.245   -112.766 -0.125  1.00 32.32  ? 86   LEU C CA    1 
ATOM   7278  C C     . LEU C 1 86  ? -7.203   -114.069 -0.929  1.00 33.82  ? 86   LEU C C     1 
ATOM   7279  O O     . LEU C 1 86  ? -8.136   -114.874 -0.857  1.00 42.80  ? 86   LEU C O     1 
ATOM   7280  C CB    . LEU C 1 86  ? -8.603   -112.070 -0.228  1.00 27.31  ? 86   LEU C CB    1 
ATOM   7281  C CG    . LEU C 1 86  ? -9.019   -111.218 0.979   1.00 24.15  ? 86   LEU C CG    1 
ATOM   7282  C CD1   . LEU C 1 86  ? -8.237   -109.930 1.072   1.00 22.62  ? 86   LEU C CD1   1 
ATOM   7283  C CD2   . LEU C 1 86  ? -10.493  -110.902 0.813   1.00 25.94  ? 86   LEU C CD2   1 
ATOM   7284  N N     . TYR C 1 87  ? -6.129   -114.279 -1.689  1.00 32.67  ? 87   TYR C N     1 
ATOM   7285  C CA    . TYR C 1 87  ? -5.981   -115.504 -2.461  1.00 35.20  ? 87   TYR C CA    1 
ATOM   7286  C C     . TYR C 1 87  ? -4.563   -116.072 -2.321  1.00 39.18  ? 87   TYR C C     1 
ATOM   7287  O O     . TYR C 1 87  ? -3.669   -115.436 -1.755  1.00 36.37  ? 87   TYR C O     1 
ATOM   7288  C CB    . TYR C 1 87  ? -6.311   -115.220 -3.920  1.00 24.89  ? 87   TYR C CB    1 
ATOM   7289  C CG    . TYR C 1 87  ? -5.463   -114.149 -4.591  1.00 26.72  ? 87   TYR C CG    1 
ATOM   7290  C CD1   . TYR C 1 87  ? -5.698   -112.787 -4.367  1.00 25.80  ? 87   TYR C CD1   1 
ATOM   7291  C CD2   . TYR C 1 87  ? -4.441   -114.490 -5.477  1.00 27.33  ? 87   TYR C CD2   1 
ATOM   7292  C CE1   . TYR C 1 87  ? -4.948   -111.799 -4.998  1.00 23.93  ? 87   TYR C CE1   1 
ATOM   7293  C CE2   . TYR C 1 87  ? -3.692   -113.506 -6.121  1.00 26.94  ? 87   TYR C CE2   1 
ATOM   7294  C CZ    . TYR C 1 87  ? -3.951   -112.160 -5.899  1.00 25.93  ? 87   TYR C CZ    1 
ATOM   7295  O OH    . TYR C 1 87  ? -3.196   -111.215 -6.555  1.00 24.94  ? 87   TYR C OH    1 
ATOM   7296  N N     . ASP C 1 88  ? -4.367   -117.282 -2.863  1.00 37.10  ? 88   ASP C N     1 
ATOM   7297  C CA    . ASP C 1 88  ? -3.074   -117.944 -2.831  1.00 32.30  ? 88   ASP C CA    1 
ATOM   7298  C C     . ASP C 1 88  ? -2.150   -117.319 -3.872  1.00 27.68  ? 88   ASP C C     1 
ATOM   7299  O O     . ASP C 1 88  ? -2.340   -117.525 -5.073  1.00 25.63  ? 88   ASP C O     1 
ATOM   7300  C CB    . ASP C 1 88  ? -3.253   -119.422 -3.114  1.00 38.82  ? 88   ASP C CB    1 
ATOM   7301  C CG    . ASP C 1 88  ? -2.004   -120.288 -2.998  1.00 47.21  ? 88   ASP C CG    1 
ATOM   7302  O OD1   . ASP C 1 88  ? -0.863   -119.734 -2.958  1.00 46.81  ? 88   ASP C OD1   1 
ATOM   7303  O OD2   . ASP C 1 88  ? -2.193   -121.517 -2.915  1.00 50.13  ? 88   ASP C OD2   1 
ATOM   7304  N N     . THR C 1 89  ? -1.115   -116.607 -3.412  1.00 25.58  ? 89   THR C N     1 
ATOM   7305  C CA    . THR C 1 89  ? -0.239   -115.929 -4.366  1.00 31.94  ? 89   THR C CA    1 
ATOM   7306  C C     . THR C 1 89  ? 0.837    -116.874 -4.906  1.00 33.94  ? 89   THR C C     1 
ATOM   7307  O O     . THR C 1 89  ? 1.711    -116.407 -5.637  1.00 34.60  ? 89   THR C O     1 
ATOM   7308  C CB    . THR C 1 89  ? 0.397    -114.670 -3.770  1.00 35.08  ? 89   THR C CB    1 
ATOM   7309  O OG1   . THR C 1 89  ? 1.255    -115.094 -2.714  1.00 34.66  ? 89   THR C OG1   1 
ATOM   7310  C CG2   . THR C 1 89  ? -0.655   -113.723 -3.218  1.00 35.48  ? 89   THR C CG2   1 
ATOM   7311  N N     . LYS C 1 90  ? 0.801    -118.163 -4.501  1.00 38.77  ? 90   LYS C N     1 
ATOM   7312  C CA    . LYS C 1 90  ? 1.658    -119.204 -5.063  1.00 44.53  ? 90   LYS C CA    1 
ATOM   7313  C C     . LYS C 1 90  ? 3.141    -118.832 -4.977  1.00 43.06  ? 90   LYS C C     1 
ATOM   7314  O O     . LYS C 1 90  ? 3.858    -118.932 -5.972  1.00 35.74  ? 90   LYS C O     1 
ATOM   7315  C CB    . LYS C 1 90  ? 1.315    -119.466 -6.538  1.00 39.40  ? 90   LYS C CB    1 
ATOM   7316  C CG    . LYS C 1 90  ? -0.141   -119.902 -6.717  1.00 40.45  ? 90   LYS C CG    1 
ATOM   7317  C CD    . LYS C 1 90  ? -0.598   -121.013 -7.654  1.00 48.79  ? 90   LYS C CD    1 
ATOM   7318  C CE    . LYS C 1 90  ? -0.117   -120.522 -8.991  1.00 61.98  ? 90   LYS C CE    1 
ATOM   7319  N NZ    . LYS C 1 90  ? -0.174   -121.556 -10.020 1.00 58.11  ? 90   LYS C NZ    1 
ATOM   7320  N N     . GLY C 1 91  ? 3.570    -118.337 -3.806  1.00 45.32  ? 91   GLY C N     1 
ATOM   7321  C CA    . GLY C 1 91  ? 4.972    -118.020 -3.586  1.00 35.93  ? 91   GLY C CA    1 
ATOM   7322  C C     . GLY C 1 91  ? 5.315    -116.546 -3.775  1.00 37.58  ? 91   GLY C C     1 
ATOM   7323  O O     . GLY C 1 91  ? 6.391    -116.119 -3.365  1.00 40.74  ? 91   GLY C O     1 
ATOM   7324  N N     . LEU C 1 92  ? 4.435    -115.746 -4.376  1.00 38.36  ? 92   LEU C N     1 
ATOM   7325  C CA    . LEU C 1 92  ? 4.801    -114.347 -4.575  1.00 32.91  ? 92   LEU C CA    1 
ATOM   7326  C C     . LEU C 1 92  ? 4.962    -113.613 -3.239  1.00 32.23  ? 92   LEU C C     1 
ATOM   7327  O O     . LEU C 1 92  ? 5.810    -112.741 -3.119  1.00 29.45  ? 92   LEU C O     1 
ATOM   7328  C CB    . LEU C 1 92  ? 3.799    -113.633 -5.462  1.00 33.84  ? 92   LEU C CB    1 
ATOM   7329  C CG    . LEU C 1 92  ? 4.153    -112.172 -5.717  1.00 36.91  ? 92   LEU C CG    1 
ATOM   7330  C CD1   . LEU C 1 92  ? 5.419    -112.003 -6.586  1.00 29.36  ? 92   LEU C CD1   1 
ATOM   7331  C CD2   . LEU C 1 92  ? 2.934    -111.424 -6.301  1.00 38.06  ? 92   LEU C CD2   1 
ATOM   7332  N N     . SER C 1 93  ? 4.148    -113.960 -2.229  1.00 30.25  ? 93   SER C N     1 
ATOM   7333  C CA    . SER C 1 93  ? 4.149    -113.218 -0.977  1.00 29.32  ? 93   SER C CA    1 
ATOM   7334  C C     . SER C 1 93  ? 3.720    -114.138 0.160   1.00 29.42  ? 93   SER C C     1 
ATOM   7335  O O     . SER C 1 93  ? 2.917    -115.037 -0.041  1.00 32.82  ? 93   SER C O     1 
ATOM   7336  C CB    . SER C 1 93  ? 3.216    -112.009 -1.061  1.00 27.32  ? 93   SER C CB    1 
ATOM   7337  O OG    . SER C 1 93  ? 3.006    -111.449 0.239   1.00 33.98  ? 93   SER C OG    1 
ATOM   7338  N N     . ASP C 1 94  ? 4.218    -113.903 1.373   1.00 32.83  ? 94   ASP C N     1 
ATOM   7339  C CA    . ASP C 1 94  ? 3.757    -114.643 2.547   1.00 39.48  ? 94   ASP C CA    1 
ATOM   7340  C C     . ASP C 1 94  ? 2.580    -113.928 3.206   1.00 36.10  ? 94   ASP C C     1 
ATOM   7341  O O     . ASP C 1 94  ? 2.006    -114.449 4.172   1.00 35.55  ? 94   ASP C O     1 
ATOM   7342  C CB    . ASP C 1 94  ? 4.877    -114.708 3.578   1.00 48.55  ? 94   ASP C CB    1 
ATOM   7343  C CG    . ASP C 1 94  ? 5.983    -115.705 3.258   1.00 70.46  ? 94   ASP C CG    1 
ATOM   7344  O OD1   . ASP C 1 94  ? 5.748    -116.580 2.391   1.00 67.30  ? 94   ASP C OD1   1 
ATOM   7345  O OD2   . ASP C 1 94  ? 7.082    -115.589 3.857   1.00 74.74  ? 94   ASP C OD2   1 
ATOM   7346  N N     . PHE C 1 95  ? 2.273    -112.705 2.727   1.00 32.23  ? 95   PHE C N     1 
ATOM   7347  C CA    . PHE C 1 95  ? 1.227    -111.906 3.360   1.00 34.90  ? 95   PHE C CA    1 
ATOM   7348  C C     . PHE C 1 95  ? -0.096   -112.178 2.634   1.00 33.71  ? 95   PHE C C     1 
ATOM   7349  O O     . PHE C 1 95  ? -0.622   -111.310 1.944   1.00 33.37  ? 95   PHE C O     1 
ATOM   7350  C CB    . PHE C 1 95  ? 1.703    -110.452 3.287   1.00 34.20  ? 95   PHE C CB    1 
ATOM   7351  C CG    . PHE C 1 95  ? 0.964    -109.485 4.205   1.00 32.28  ? 95   PHE C CG    1 
ATOM   7352  C CD1   . PHE C 1 95  ? 0.742    -109.802 5.553   1.00 26.85  ? 95   PHE C CD1   1 
ATOM   7353  C CD2   . PHE C 1 95  ? 0.491    -108.259 3.711   1.00 26.60  ? 95   PHE C CD2   1 
ATOM   7354  C CE1   . PHE C 1 95  ? 0.098    -108.898 6.385   1.00 24.07  ? 95   PHE C CE1   1 
ATOM   7355  C CE2   . PHE C 1 95  ? -0.148   -107.354 4.550   1.00 23.42  ? 95   PHE C CE2   1 
ATOM   7356  C CZ    . PHE C 1 95  ? -0.362   -107.686 5.881   1.00 24.81  ? 95   PHE C CZ    1 
ATOM   7357  N N     . ASP C 1 96  ? -0.578   -113.426 2.731   1.00 30.31  ? 96   ASP C N     1 
ATOM   7358  C CA    . ASP C 1 96  ? -1.748   -113.852 1.991   1.00 29.30  ? 96   ASP C CA    1 
ATOM   7359  C C     . ASP C 1 96  ? -2.551   -114.815 2.856   1.00 29.74  ? 96   ASP C C     1 
ATOM   7360  O O     . ASP C 1 96  ? -2.126   -115.240 3.925   1.00 32.89  ? 96   ASP C O     1 
ATOM   7361  C CB    . ASP C 1 96  ? -1.383   -114.344 0.594   1.00 30.46  ? 96   ASP C CB    1 
ATOM   7362  C CG    . ASP C 1 96  ? -0.816   -115.759 0.474   1.00 34.68  ? 96   ASP C CG    1 
ATOM   7363  O OD1   . ASP C 1 96  ? -0.904   -116.533 1.480   1.00 37.12  ? 96   ASP C OD1   1 
ATOM   7364  O OD2   . ASP C 1 96  ? -0.318   -116.101 -0.651  1.00 32.20  ? 96   ASP C OD2   1 
ATOM   7365  N N     . VAL C 1 97  ? -3.726   -115.174 2.363   1.00 31.21  ? 97   VAL C N     1 
ATOM   7366  C CA    . VAL C 1 97  ? -4.691   -115.892 3.176   1.00 33.74  ? 97   VAL C CA    1 
ATOM   7367  C C     . VAL C 1 97  ? -4.204   -117.313 3.466   1.00 37.39  ? 97   VAL C C     1 
ATOM   7368  O O     . VAL C 1 97  ? -4.629   -117.897 4.466   1.00 36.49  ? 97   VAL C O     1 
ATOM   7369  C CB    . VAL C 1 97  ? -6.040   -115.886 2.434   1.00 29.42  ? 97   VAL C CB    1 
ATOM   7370  C CG1   . VAL C 1 97  ? -5.947   -116.652 1.109   1.00 26.78  ? 97   VAL C CG1   1 
ATOM   7371  C CG2   . VAL C 1 97  ? -7.150   -116.403 3.338   1.00 26.20  ? 97   VAL C CG2   1 
ATOM   7372  N N     . MET C 1 98  ? -3.307   -117.859 2.617   1.00 35.22  ? 98   MET C N     1 
ATOM   7373  C CA    . MET C 1 98  ? -2.779   -119.190 2.879   1.00 38.87  ? 98   MET C CA    1 
ATOM   7374  C C     . MET C 1 98  ? -1.860   -119.196 4.109   1.00 39.69  ? 98   MET C C     1 
ATOM   7375  O O     . MET C 1 98  ? -1.647   -120.244 4.695   1.00 47.02  ? 98   MET C O     1 
ATOM   7376  C CB    . MET C 1 98  ? -2.066   -119.805 1.671   1.00 37.76  ? 98   MET C CB    1 
ATOM   7377  C CG    . MET C 1 98  ? -2.940   -119.885 0.436   1.00 45.41  ? 98   MET C CG    1 
ATOM   7378  S SD    . MET C 1 98  ? -4.566   -120.657 0.612   1.00 52.43  ? 98   MET C SD    1 
ATOM   7379  C CE    . MET C 1 98  ? -4.275   -122.379 1.048   1.00 46.60  ? 98   MET C CE    1 
ATOM   7380  N N     . HIS C 1 99  ? -1.384   -118.031 4.547   1.00 36.98  ? 99   HIS C N     1 
ATOM   7381  C CA    . HIS C 1 99  ? -0.551   -117.931 5.732   1.00 37.75  ? 99   HIS C CA    1 
ATOM   7382  C C     . HIS C 1 99  ? -1.368   -117.421 6.913   1.00 41.16  ? 99   HIS C C     1 
ATOM   7383  O O     . HIS C 1 99  ? -0.799   -117.029 7.930   1.00 42.55  ? 99   HIS C O     1 
ATOM   7384  C CB    . HIS C 1 99  ? 0.657    -117.020 5.465   1.00 34.65  ? 99   HIS C CB    1 
ATOM   7385  C CG    . HIS C 1 99  ? 1.567    -117.625 4.444   1.00 42.52  ? 99   HIS C CG    1 
ATOM   7386  N ND1   . HIS C 1 99  ? 1.272    -117.640 3.094   1.00 44.09  ? 99   HIS C ND1   1 
ATOM   7387  C CD2   . HIS C 1 99  ? 2.726    -118.305 4.583   1.00 39.01  ? 99   HIS C CD2   1 
ATOM   7388  C CE1   . HIS C 1 99  ? 2.252    -118.252 2.435   1.00 41.23  ? 99   HIS C CE1   1 
ATOM   7389  N NE2   . HIS C 1 99  ? 3.137    -118.657 3.329   1.00 40.22  ? 99   HIS C NE2   1 
ATOM   7390  N N     . ALA C 1 100 ? -2.696   -117.398 6.761   1.00 38.64  ? 100  ALA C N     1 
ATOM   7391  C CA    . ALA C 1 100 ? -3.566   -116.968 7.841   1.00 35.86  ? 100  ALA C CA    1 
ATOM   7392  C C     . ALA C 1 100 ? -4.301   -118.197 8.354   1.00 33.50  ? 100  ALA C C     1 
ATOM   7393  O O     . ALA C 1 100 ? -4.448   -119.162 7.621   1.00 35.07  ? 100  ALA C O     1 
ATOM   7394  C CB    . ALA C 1 100 ? -4.534   -115.913 7.327   1.00 36.27  ? 100  ALA C CB    1 
ATOM   7395  N N     . PRO C 1 101 ? -4.838   -118.195 9.595   1.00 33.86  ? 101  PRO C N     1 
ATOM   7396  C CA    . PRO C 1 101 ? -5.653   -119.324 10.050  1.00 33.08  ? 101  PRO C CA    1 
ATOM   7397  C C     . PRO C 1 101 ? -6.759   -119.735 9.071   1.00 40.03  ? 101  PRO C C     1 
ATOM   7398  O O     . PRO C 1 101 ? -7.125   -120.892 9.020   1.00 45.27  ? 101  PRO C O     1 
ATOM   7399  C CB    . PRO C 1 101 ? -6.170   -118.917 11.437  1.00 29.56  ? 101  PRO C CB    1 
ATOM   7400  C CG    . PRO C 1 101 ? -5.744   -117.469 11.591  1.00 30.47  ? 101  PRO C CG    1 
ATOM   7401  C CD    . PRO C 1 101 ? -4.674   -117.125 10.599  1.00 29.70  ? 101  PRO C CD    1 
ATOM   7402  N N     . ALA C 1 102 ? -7.286   -118.813 8.253   1.00 42.90  ? 102  ALA C N     1 
ATOM   7403  C CA    . ALA C 1 102 ? -8.331   -119.187 7.315   1.00 40.05  ? 102  ALA C CA    1 
ATOM   7404  C C     . ALA C 1 102 ? -7.888   -120.361 6.423   1.00 42.04  ? 102  ALA C C     1 
ATOM   7405  O O     . ALA C 1 102 ? -8.680   -121.267 6.178   1.00 36.37  ? 102  ALA C O     1 
ATOM   7406  C CB    . ALA C 1 102 ? -8.742   -117.986 6.497   1.00 38.07  ? 102  ALA C CB    1 
ATOM   7407  N N     . ARG C 1 103 ? -6.653   -120.302 5.894   1.00 39.93  ? 103  ARG C N     1 
ATOM   7408  C CA    . ARG C 1 103 ? -6.065   -121.334 5.045   1.00 45.55  ? 103  ARG C CA    1 
ATOM   7409  C C     . ARG C 1 103 ? -7.006   -121.788 3.929   1.00 45.03  ? 103  ARG C C     1 
ATOM   7410  O O     . ARG C 1 103 ? -7.103   -122.973 3.662   1.00 53.43  ? 103  ARG C O     1 
ATOM   7411  C CB    . ARG C 1 103 ? -5.681   -122.616 5.790   1.00 50.87  ? 103  ARG C CB    1 
ATOM   7412  C CG    . ARG C 1 103 ? -4.419   -122.488 6.624   1.00 64.88  ? 103  ARG C CG    1 
ATOM   7413  C CD    . ARG C 1 103 ? -4.203   -123.886 7.169   1.00 82.09  ? 103  ARG C CD    1 
ATOM   7414  N NE    . ARG C 1 103 ? -2.853   -124.104 7.711   1.00 94.75  ? 103  ARG C NE    1 
ATOM   7415  C CZ    . ARG C 1 103 ? -2.447   -124.022 8.985   1.00 95.15  ? 103  ARG C CZ    1 
ATOM   7416  N NH1   . ARG C 1 103 ? -3.235   -123.546 9.946   1.00 85.36  ? 103  ARG C NH1   1 
ATOM   7417  N NH2   . ARG C 1 103 ? -1.215   -124.397 9.288   1.00 107.74 ? 103  ARG C NH2   1 
ATOM   7418  N N     . ARG C 1 104 ? -7.686   -120.855 3.272   1.00 42.38  ? 104  ARG C N     1 
ATOM   7419  C CA    . ARG C 1 104 ? -8.586   -121.174 2.172   1.00 35.34  ? 104  ARG C CA    1 
ATOM   7420  C C     . ARG C 1 104 ? -8.376   -120.073 1.136   1.00 38.30  ? 104  ARG C C     1 
ATOM   7421  O O     . ARG C 1 104 ? -8.205   -118.897 1.497   1.00 39.51  ? 104  ARG C O     1 
ATOM   7422  C CB    . ARG C 1 104 ? -10.057  -121.006 2.577   1.00 36.58  ? 104  ARG C CB    1 
ATOM   7423  C CG    . ARG C 1 104 ? -10.617  -121.964 3.609   1.00 38.87  ? 104  ARG C CG    1 
ATOM   7424  C CD    . ARG C 1 104 ? -11.575  -121.322 4.616   1.00 40.51  ? 104  ARG C CD    1 
ATOM   7425  N NE    . ARG C 1 104 ? -12.768  -120.754 3.994   1.00 40.71  ? 104  ARG C NE    1 
ATOM   7426  C CZ    . ARG C 1 104 ? -13.673  -120.012 4.675   1.00 45.18  ? 104  ARG C CZ    1 
ATOM   7427  N NH1   . ARG C 1 104 ? -13.476  -119.786 5.961   1.00 37.82  ? 104  ARG C NH1   1 
ATOM   7428  N NH2   . ARG C 1 104 ? -14.744  -119.494 4.037   1.00 40.54  ? 104  ARG C NH2   1 
ATOM   7429  N N     . ASP C 1 105 ? -8.412   -120.455 -0.146  1.00 31.81  ? 105  ASP C N     1 
ATOM   7430  C CA    . ASP C 1 105 ? -8.407   -119.466 -1.196  1.00 31.63  ? 105  ASP C CA    1 
ATOM   7431  C C     . ASP C 1 105 ? -9.804   -118.839 -1.323  1.00 36.90  ? 105  ASP C C     1 
ATOM   7432  O O     . ASP C 1 105 ? -10.690  -119.426 -1.928  1.00 41.08  ? 105  ASP C O     1 
ATOM   7433  C CB    . ASP C 1 105 ? -7.809   -120.014 -2.478  1.00 28.43  ? 105  ASP C CB    1 
ATOM   7434  C CG    . ASP C 1 105 ? -7.563   -118.924 -3.505  1.00 33.96  ? 105  ASP C CG    1 
ATOM   7435  O OD1   . ASP C 1 105 ? -8.401   -117.983 -3.544  1.00 39.28  ? 105  ASP C OD1   1 
ATOM   7436  O OD2   . ASP C 1 105 ? -6.567   -119.035 -4.284  1.00 29.58  ? 105  ASP C OD2   1 
ATOM   7437  N N     . LEU C 1 106 ? -9.981   -117.625 -0.765  1.00 34.96  ? 106  LEU C N     1 
ATOM   7438  C CA    . LEU C 1 106 ? -11.280  -116.978 -0.681  1.00 29.73  ? 106  LEU C CA    1 
ATOM   7439  C C     . LEU C 1 106 ? -11.740  -116.520 -2.064  1.00 29.14  ? 106  LEU C C     1 
ATOM   7440  O O     . LEU C 1 106 ? -12.928  -116.555 -2.362  1.00 33.12  ? 106  LEU C O     1 
ATOM   7441  C CB    . LEU C 1 106 ? -11.200  -115.829 0.315   1.00 24.44  ? 106  LEU C CB    1 
ATOM   7442  C CG    . LEU C 1 106 ? -10.794  -116.253 1.716   1.00 25.00  ? 106  LEU C CG    1 
ATOM   7443  C CD1   . LEU C 1 106 ? -10.478  -115.037 2.571   1.00 25.45  ? 106  LEU C CD1   1 
ATOM   7444  C CD2   . LEU C 1 106 ? -11.902  -117.078 2.336   1.00 23.93  ? 106  LEU C CD2   1 
ATOM   7445  N N     . ILE C 1 107 ? -10.799  -116.139 -2.921  1.00 28.13  ? 107  ILE C N     1 
ATOM   7446  C CA    . ILE C 1 107 ? -11.139  -115.805 -4.295  1.00 29.38  ? 107  ILE C CA    1 
ATOM   7447  C C     . ILE C 1 107 ? -11.712  -117.023 -5.027  1.00 32.80  ? 107  ILE C C     1 
ATOM   7448  O O     . ILE C 1 107 ? -12.648  -116.873 -5.829  1.00 31.13  ? 107  ILE C O     1 
ATOM   7449  C CB    . ILE C 1 107 ? -9.952   -115.138 -5.025  1.00 28.35  ? 107  ILE C CB    1 
ATOM   7450  C CG1   . ILE C 1 107 ? -9.467   -113.854 -4.322  1.00 29.99  ? 107  ILE C CG1   1 
ATOM   7451  C CG2   . ILE C 1 107 ? -10.246  -114.883 -6.500  1.00 26.80  ? 107  ILE C CG2   1 
ATOM   7452  C CD1   . ILE C 1 107 ? -10.562  -113.000 -3.682  1.00 29.77  ? 107  ILE C CD1   1 
ATOM   7453  N N     . ALA C 1 108 ? -11.186  -118.234 -4.741  1.00 34.92  ? 108  ALA C N     1 
ATOM   7454  C CA    . ALA C 1 108 ? -11.707  -119.428 -5.400  1.00 35.32  ? 108  ALA C CA    1 
ATOM   7455  C C     . ALA C 1 108 ? -13.153  -119.663 -4.953  1.00 34.19  ? 108  ALA C C     1 
ATOM   7456  O O     . ALA C 1 108 ? -14.019  -119.944 -5.791  1.00 32.74  ? 108  ALA C O     1 
ATOM   7457  C CB    . ALA C 1 108 ? -10.827  -120.657 -5.188  1.00 25.89  ? 108  ALA C CB    1 
ATOM   7458  N N     . GLU C 1 109 ? -13.405  -119.504 -3.644  1.00 32.08  ? 109  GLU C N     1 
ATOM   7459  C CA    . GLU C 1 109 ? -14.761  -119.632 -3.118  1.00 31.59  ? 109  GLU C CA    1 
ATOM   7460  C C     . GLU C 1 109 ? -15.699  -118.620 -3.779  1.00 32.17  ? 109  GLU C C     1 
ATOM   7461  O O     . GLU C 1 109 ? -16.811  -118.979 -4.184  1.00 36.26  ? 109  GLU C O     1 
ATOM   7462  C CB    . GLU C 1 109 ? -14.810  -119.483 -1.604  1.00 29.87  ? 109  GLU C CB    1 
ATOM   7463  C CG    . GLU C 1 109 ? -13.965  -120.523 -0.876  1.00 30.96  ? 109  GLU C CG    1 
ATOM   7464  C CD    . GLU C 1 109 ? -14.047  -120.414 0.627   1.00 37.30  ? 109  GLU C CD    1 
ATOM   7465  O OE1   . GLU C 1 109 ? -14.794  -119.543 1.128   1.00 45.81  ? 109  GLU C OE1   1 
ATOM   7466  O OE2   . GLU C 1 109 ? -13.348  -121.185 1.321   1.00 45.34  ? 109  GLU C OE2   1 
ATOM   7467  N N     . PHE C 1 110 ? -15.202  -117.387 -3.953  1.00 29.59  ? 110  PHE C N     1 
ATOM   7468  C CA    . PHE C 1 110 ? -15.988  -116.281 -4.477  1.00 30.75  ? 110  PHE C CA    1 
ATOM   7469  C C     . PHE C 1 110 ? -16.379  -116.550 -5.927  1.00 29.81  ? 110  PHE C C     1 
ATOM   7470  O O     . PHE C 1 110 ? -17.537  -116.358 -6.297  1.00 30.57  ? 110  PHE C O     1 
ATOM   7471  C CB    . PHE C 1 110 ? -15.150  -115.011 -4.320  1.00 26.14  ? 110  PHE C CB    1 
ATOM   7472  C CG    . PHE C 1 110 ? -15.648  -113.820 -5.126  1.00 26.20  ? 110  PHE C CG    1 
ATOM   7473  C CD1   . PHE C 1 110 ? -16.848  -113.175 -4.789  1.00 27.43  ? 110  PHE C CD1   1 
ATOM   7474  C CD2   . PHE C 1 110 ? -14.896  -113.304 -6.186  1.00 24.87  ? 110  PHE C CD2   1 
ATOM   7475  C CE1   . PHE C 1 110 ? -17.310  -112.079 -5.510  1.00 24.49  ? 110  PHE C CE1   1 
ATOM   7476  C CE2   . PHE C 1 110 ? -15.334  -112.189 -6.905  1.00 22.78  ? 110  PHE C CE2   1 
ATOM   7477  C CZ    . PHE C 1 110 ? -16.539  -111.573 -6.563  1.00 27.57  ? 110  PHE C CZ    1 
ATOM   7478  N N     . VAL C 1 111 ? -15.408  -116.991 -6.728  1.00 30.31  ? 111  VAL C N     1 
ATOM   7479  C CA    . VAL C 1 111 ? -15.660  -117.190 -8.150  1.00 36.16  ? 111  VAL C CA    1 
ATOM   7480  C C     . VAL C 1 111 ? -16.688  -118.304 -8.358  1.00 31.71  ? 111  VAL C C     1 
ATOM   7481  O O     . VAL C 1 111 ? -17.569  -118.198 -9.196  1.00 36.16  ? 111  VAL C O     1 
ATOM   7482  C CB    . VAL C 1 111 ? -14.412  -117.412 -9.031  1.00 36.72  ? 111  VAL C CB    1 
ATOM   7483  C CG1   . VAL C 1 111 ? -13.538  -116.164 -9.112  1.00 32.13  ? 111  VAL C CG1   1 
ATOM   7484  C CG2   . VAL C 1 111 ? -13.604  -118.639 -8.647  1.00 48.66  ? 111  VAL C CG2   1 
ATOM   7485  N N     . ALA C 1 112 ? -16.586  -119.380 -7.592  1.00 30.53  ? 112  ALA C N     1 
ATOM   7486  C CA    . ALA C 1 112 ? -17.511  -120.502 -7.725  1.00 33.10  ? 112  ALA C CA    1 
ATOM   7487  C C     . ALA C 1 112 ? -18.922  -120.051 -7.323  1.00 32.75  ? 112  ALA C C     1 
ATOM   7488  O O     . ALA C 1 112 ? -19.900  -120.341 -8.019  1.00 34.36  ? 112  ALA C O     1 
ATOM   7489  C CB    . ALA C 1 112 ? -17.009  -121.713 -6.926  1.00 25.96  ? 112  ALA C CB    1 
ATOM   7490  N N     . ALA C 1 113 ? -19.021  -119.278 -6.231  1.00 33.76  ? 113  ALA C N     1 
ATOM   7491  C CA    . ALA C 1 113 ? -20.322  -118.779 -5.768  1.00 30.29  ? 113  ALA C CA    1 
ATOM   7492  C C     . ALA C 1 113 ? -20.952  -117.870 -6.826  1.00 26.96  ? 113  ALA C C     1 
ATOM   7493  O O     . ALA C 1 113 ? -22.141  -118.004 -7.104  1.00 29.32  ? 113  ALA C O     1 
ATOM   7494  C CB    . ALA C 1 113 ? -20.195  -118.093 -4.431  1.00 26.95  ? 113  ALA C CB    1 
ATOM   7495  N N     . CYS C 1 114 ? -20.145  -117.001 -7.459  1.00 25.64  ? 114  CYS C N     1 
ATOM   7496  C CA    . CYS C 1 114 ? -20.660  -116.122 -8.497  1.00 29.62  ? 114  CYS C CA    1 
ATOM   7497  C C     . CYS C 1 114 ? -21.213  -116.931 -9.669  1.00 36.57  ? 114  CYS C C     1 
ATOM   7498  O O     . CYS C 1 114 ? -22.280  -116.619 -10.195 1.00 35.63  ? 114  CYS C O     1 
ATOM   7499  C CB    . CYS C 1 114 ? -19.621  -115.151 -9.054  1.00 28.30  ? 114  CYS C CB    1 
ATOM   7500  S SG    . CYS C 1 114 ? -19.191  -113.863 -7.867  1.00 33.97  ? 114  CYS C SG    1 
ATOM   7501  N N     . ARG C 1 115 ? -20.466  -117.960 -10.084 1.00 37.97  ? 115  ARG C N     1 
ATOM   7502  C CA    . ARG C 1 115 ? -20.848  -118.710 -11.265 1.00 40.29  ? 115  ARG C CA    1 
ATOM   7503  C C     . ARG C 1 115 ? -22.157  -119.446 -11.011 1.00 37.03  ? 115  ARG C C     1 
ATOM   7504  O O     . ARG C 1 115 ? -22.975  -119.511 -11.906 1.00 36.23  ? 115  ARG C O     1 
ATOM   7505  C CB    . ARG C 1 115 ? -19.788  -119.701 -11.737 1.00 44.01  ? 115  ARG C CB    1 
ATOM   7506  C CG    . ARG C 1 115 ? -18.805  -118.882 -12.563 1.00 51.18  ? 115  ARG C CG    1 
ATOM   7507  C CD    . ARG C 1 115 ? -17.540  -119.688 -12.671 1.00 52.45  ? 115  ARG C CD    1 
ATOM   7508  N NE    . ARG C 1 115 ? -16.508  -118.860 -13.292 1.00 55.86  ? 115  ARG C NE    1 
ATOM   7509  C CZ    . ARG C 1 115 ? -15.213  -119.136 -13.127 1.00 50.04  ? 115  ARG C CZ    1 
ATOM   7510  N NH1   . ARG C 1 115 ? -14.841  -120.195 -12.432 1.00 40.90  ? 115  ARG C NH1   1 
ATOM   7511  N NH2   . ARG C 1 115 ? -14.301  -118.330 -13.641 1.00 41.07  ? 115  ARG C NH2   1 
ATOM   7512  N N     . GLU C 1 116 ? -22.357  -119.973 -9.799  1.00 34.01  ? 116  GLU C N     1 
ATOM   7513  C CA    . GLU C 1 116 ? -23.590  -120.680 -9.533  1.00 40.21  ? 116  GLU C CA    1 
ATOM   7514  C C     . GLU C 1 116 ? -24.794  -119.741 -9.576  1.00 45.11  ? 116  GLU C C     1 
ATOM   7515  O O     . GLU C 1 116 ? -25.892  -120.218 -9.804  1.00 42.41  ? 116  GLU C O     1 
ATOM   7516  C CB    . GLU C 1 116 ? -23.526  -121.720 -8.420  1.00 47.12  ? 116  GLU C CB    1 
ATOM   7517  C CG    . GLU C 1 116 ? -23.529  -121.174 -7.002  1.00 80.25  ? 116  GLU C CG    1 
ATOM   7518  C CD    . GLU C 1 116 ? -22.944  -122.202 -6.057  1.00 90.55  ? 116  GLU C CD    1 
ATOM   7519  O OE1   . GLU C 1 116 ? -22.381  -123.183 -6.588  1.00 96.23  ? 116  GLU C OE1   1 
ATOM   7520  O OE2   . GLU C 1 116 ? -23.059  -122.040 -4.822  1.00 87.44  ? 116  GLU C OE2   1 
ATOM   7521  N N     . GLU C 1 117 ? -24.595  -118.422 -9.393  1.00 43.39  ? 117  GLU C N     1 
ATOM   7522  C CA    . GLU C 1 117 ? -25.705  -117.478 -9.368  1.00 35.32  ? 117  GLU C CA    1 
ATOM   7523  C C     . GLU C 1 117 ? -25.773  -116.692 -10.674 1.00 34.79  ? 117  GLU C C     1 
ATOM   7524  O O     . GLU C 1 117 ? -26.534  -115.732 -10.782 1.00 38.05  ? 117  GLU C O     1 
ATOM   7525  C CB    . GLU C 1 117 ? -25.622  -116.523 -8.179  1.00 33.51  ? 117  GLU C CB    1 
ATOM   7526  C CG    . GLU C 1 117 ? -25.887  -117.217 -6.843  1.00 41.74  ? 117  GLU C CG    1 
ATOM   7527  C CD    . GLU C 1 117 ? -27.360  -117.486 -6.482  1.00 48.12  ? 117  GLU C CD    1 
ATOM   7528  O OE1   . GLU C 1 117 ? -28.255  -117.388 -7.358  1.00 43.69  ? 117  GLU C OE1   1 
ATOM   7529  O OE2   . GLU C 1 117 ? -27.650  -117.726 -5.275  1.00 58.04  ? 117  GLU C OE2   1 
ATOM   7530  N N     . ASP C 1 118 ? -24.951  -117.074 -11.656 1.00 34.55  ? 118  ASP C N     1 
ATOM   7531  C CA    . ASP C 1 118 ? -24.875  -116.365 -12.923 1.00 38.34  ? 118  ASP C CA    1 
ATOM   7532  C C     . ASP C 1 118 ? -24.434  -114.897 -12.733 1.00 37.67  ? 118  ASP C C     1 
ATOM   7533  O O     . ASP C 1 118 ? -24.863  -114.001 -13.462 1.00 36.27  ? 118  ASP C O     1 
ATOM   7534  C CB    . ASP C 1 118 ? -26.124  -116.631 -13.755 1.00 44.03  ? 118  ASP C CB    1 
ATOM   7535  C CG    . ASP C 1 118 ? -26.034  -116.261 -15.228 1.00 69.80  ? 118  ASP C CG    1 
ATOM   7536  O OD1   . ASP C 1 118 ? -24.995  -116.577 -15.849 1.00 90.14  ? 118  ASP C OD1   1 
ATOM   7537  O OD2   . ASP C 1 118 ? -27.010  -115.676 -15.757 1.00 80.39  ? 118  ASP C OD2   1 
ATOM   7538  N N     . LEU C 1 119 ? -23.520  -114.636 -11.793 1.00 33.05  ? 119  LEU C N     1 
ATOM   7539  C CA    . LEU C 1 119 ? -22.961  -113.298 -11.626 1.00 30.51  ? 119  LEU C CA    1 
ATOM   7540  C C     . LEU C 1 119 ? -21.547  -113.276 -12.199 1.00 30.41  ? 119  LEU C C     1 
ATOM   7541  O O     . LEU C 1 119 ? -20.821  -114.260 -12.058 1.00 35.06  ? 119  LEU C O     1 
ATOM   7542  C CB    . LEU C 1 119 ? -22.918  -113.001 -10.124 1.00 25.74  ? 119  LEU C CB    1 
ATOM   7543  C CG    . LEU C 1 119 ? -24.258  -113.070 -9.393  1.00 26.50  ? 119  LEU C CG    1 
ATOM   7544  C CD1   . LEU C 1 119 ? -24.081  -112.856 -7.919  1.00 28.76  ? 119  LEU C CD1   1 
ATOM   7545  C CD2   . LEU C 1 119 ? -25.238  -112.055 -9.956  1.00 26.28  ? 119  LEU C CD2   1 
ATOM   7546  N N     . LEU C 1 120 ? -21.141  -112.141 -12.775 1.00 27.52  ? 120  LEU C N     1 
ATOM   7547  C CA    . LEU C 1 120 ? -19.742  -112.001 -13.165 1.00 29.15  ? 120  LEU C CA    1 
ATOM   7548  C C     . LEU C 1 120 ? -18.857  -111.653 -11.956 1.00 30.44  ? 120  LEU C C     1 
ATOM   7549  O O     . LEU C 1 120 ? -19.145  -110.699 -11.239 1.00 33.41  ? 120  LEU C O     1 
ATOM   7550  C CB    . LEU C 1 120 ? -19.575  -110.979 -14.288 1.00 25.74  ? 120  LEU C CB    1 
ATOM   7551  C CG    . LEU C 1 120 ? -20.228  -111.370 -15.619 1.00 33.40  ? 120  LEU C CG    1 
ATOM   7552  C CD1   . LEU C 1 120 ? -19.837  -110.329 -16.649 1.00 27.17  ? 120  LEU C CD1   1 
ATOM   7553  C CD2   . LEU C 1 120 ? -19.871  -112.813 -16.097 1.00 28.29  ? 120  LEU C CD2   1 
ATOM   7554  N N     . PRO C 1 121 ? -17.759  -112.404 -11.687 1.00 31.68  ? 121  PRO C N     1 
ATOM   7555  C CA    . PRO C 1 121 ? -16.810  -112.051 -10.630 1.00 28.04  ? 121  PRO C CA    1 
ATOM   7556  C C     . PRO C 1 121 ? -15.777  -111.029 -11.105 1.00 29.30  ? 121  PRO C C     1 
ATOM   7557  O O     . PRO C 1 121 ? -15.173  -111.189 -12.172 1.00 28.64  ? 121  PRO C O     1 
ATOM   7558  C CB    . PRO C 1 121 ? -16.152  -113.373 -10.255 1.00 27.62  ? 121  PRO C CB    1 
ATOM   7559  C CG    . PRO C 1 121 ? -16.144  -114.076 -11.620 1.00 31.56  ? 121  PRO C CG    1 
ATOM   7560  C CD    . PRO C 1 121 ? -17.397  -113.665 -12.369 1.00 31.00  ? 121  PRO C CD    1 
ATOM   7561  N N     . PHE C 1 122 ? -15.627  -109.933 -10.347 1.00 24.60  ? 122  PHE C N     1 
ATOM   7562  C CA    . PHE C 1 122 ? -14.655  -108.916 -10.690 1.00 23.82  ? 122  PHE C CA    1 
ATOM   7563  C C     . PHE C 1 122 ? -13.665  -108.806 -9.533  1.00 26.96  ? 122  PHE C C     1 
ATOM   7564  O O     . PHE C 1 122 ? -14.051  -108.947 -8.363  1.00 25.39  ? 122  PHE C O     1 
ATOM   7565  C CB    . PHE C 1 122 ? -15.278  -107.540 -10.880 1.00 22.11  ? 122  PHE C CB    1 
ATOM   7566  C CG    . PHE C 1 122 ? -15.894  -107.227 -12.232 1.00 21.13  ? 122  PHE C CG    1 
ATOM   7567  C CD1   . PHE C 1 122 ? -16.832  -108.066 -12.814 1.00 20.95  ? 122  PHE C CD1   1 
ATOM   7568  C CD2   . PHE C 1 122 ? -15.512  -106.083 -12.925 1.00 22.25  ? 122  PHE C CD2   1 
ATOM   7569  C CE1   . PHE C 1 122 ? -17.382  -107.756 -14.067 1.00 18.21  ? 122  PHE C CE1   1 
ATOM   7570  C CE2   . PHE C 1 122 ? -16.057  -105.781 -14.174 1.00 22.01  ? 122  PHE C CE2   1 
ATOM   7571  C CZ    . PHE C 1 122 ? -16.981  -106.617 -14.738 1.00 17.94  ? 122  PHE C CZ    1 
ATOM   7572  N N     . PHE C 1 123 ? -12.399  -108.536 -9.873  1.00 25.04  ? 123  PHE C N     1 
ATOM   7573  C CA    . PHE C 1 123 ? -11.348  -108.499 -8.875  1.00 25.23  ? 123  PHE C CA    1 
ATOM   7574  C C     . PHE C 1 123 ? -10.839  -107.072 -8.728  1.00 24.62  ? 123  PHE C C     1 
ATOM   7575  O O     . PHE C 1 123 ? -10.299  -106.496 -9.674  1.00 27.16  ? 123  PHE C O     1 
ATOM   7576  C CB    . PHE C 1 123 ? -10.182  -109.375 -9.331  1.00 26.73  ? 123  PHE C CB    1 
ATOM   7577  C CG    . PHE C 1 123 ? -10.497  -110.854 -9.471  1.00 28.09  ? 123  PHE C CG    1 
ATOM   7578  C CD1   . PHE C 1 123 ? -11.464  -111.469 -8.676  1.00 30.97  ? 123  PHE C CD1   1 
ATOM   7579  C CD2   . PHE C 1 123 ? -9.775   -111.641 -10.369 1.00 28.11  ? 123  PHE C CD2   1 
ATOM   7580  C CE1   . PHE C 1 123 ? -11.744  -112.839 -8.809  1.00 27.87  ? 123  PHE C CE1   1 
ATOM   7581  C CE2   . PHE C 1 123 ? -10.031  -113.009 -10.468 1.00 24.86  ? 123  PHE C CE2   1 
ATOM   7582  C CZ    . PHE C 1 123 ? -11.016  -113.604 -9.699  1.00 26.88  ? 123  PHE C CZ    1 
ATOM   7583  N N     . TYR C 1 124 ? -11.030  -106.504 -7.533  1.00 22.03  ? 124  TYR C N     1 
ATOM   7584  C CA    . TYR C 1 124 ? -10.442  -105.199 -7.266  1.00 21.50  ? 124  TYR C CA    1 
ATOM   7585  C C     . TYR C 1 124 ? -8.991   -105.465 -6.867  1.00 24.02  ? 124  TYR C C     1 
ATOM   7586  O O     . TYR C 1 124 ? -8.697   -106.394 -6.084  1.00 21.35  ? 124  TYR C O     1 
ATOM   7587  C CB    . TYR C 1 124 ? -11.217  -104.535 -6.114  1.00 20.54  ? 124  TYR C CB    1 
ATOM   7588  C CG    . TYR C 1 124 ? -10.514  -103.360 -5.449  1.00 22.02  ? 124  TYR C CG    1 
ATOM   7589  C CD1   . TYR C 1 124 ? -9.400   -103.558 -4.638  1.00 22.06  ? 124  TYR C CD1   1 
ATOM   7590  C CD2   . TYR C 1 124 ? -10.940  -102.045 -5.646  1.00 23.43  ? 124  TYR C CD2   1 
ATOM   7591  C CE1   . TYR C 1 124 ? -8.741   -102.496 -4.035  1.00 24.07  ? 124  TYR C CE1   1 
ATOM   7592  C CE2   . TYR C 1 124 ? -10.309  -100.971 -5.036  1.00 21.89  ? 124  TYR C CE2   1 
ATOM   7593  C CZ    . TYR C 1 124 ? -9.196   -101.202 -4.242  1.00 25.12  ? 124  TYR C CZ    1 
ATOM   7594  O OH    . TYR C 1 124 ? -8.526   -100.172 -3.645  1.00 26.37  ? 124  TYR C OH    1 
ATOM   7595  N N     . MET C 1 125 ? -8.083   -104.624 -7.368  1.00 24.20  ? 125  MET C N     1 
ATOM   7596  C CA    . MET C 1 125 ? -6.678   -104.743 -7.025  1.00 25.82  ? 125  MET C CA    1 
ATOM   7597  C C     . MET C 1 125 ? -6.125   -103.343 -6.784  1.00 25.47  ? 125  MET C C     1 
ATOM   7598  O O     . MET C 1 125 ? -6.232   -102.480 -7.659  1.00 26.54  ? 125  MET C O     1 
ATOM   7599  C CB    . MET C 1 125 ? -5.901   -105.458 -8.141  1.00 29.03  ? 125  MET C CB    1 
ATOM   7600  C CG    . MET C 1 125 ? -4.371   -105.323 -8.034  1.00 27.84  ? 125  MET C CG    1 
ATOM   7601  S SD    . MET C 1 125 ? -3.662   -106.195 -6.618  1.00 30.64  ? 125  MET C SD    1 
ATOM   7602  C CE    . MET C 1 125 ? -4.035   -107.909 -7.001  1.00 27.73  ? 125  MET C CE    1 
ATOM   7603  N N     . ALA C 1 126 ? -5.569   -103.110 -5.579  1.00 25.72  ? 126  ALA C N     1 
ATOM   7604  C CA    . ALA C 1 126 ? -4.951   -101.808 -5.311  1.00 28.86  ? 126  ALA C CA    1 
ATOM   7605  C C     . ALA C 1 126 ? -3.550   -101.750 -5.933  1.00 26.63  ? 126  ALA C C     1 
ATOM   7606  O O     . ALA C 1 126 ? -2.743   -102.652 -5.746  1.00 25.68  ? 126  ALA C O     1 
ATOM   7607  C CB    . ALA C 1 126 ? -4.886   -101.558 -3.828  1.00 26.50  ? 126  ALA C CB    1 
ATOM   7608  N N     . THR C 1 127 ? -3.254   -100.683 -6.666  1.00 27.10  ? 127  THR C N     1 
ATOM   7609  C CA    . THR C 1 127 ? -1.942   -100.560 -7.267  1.00 25.56  ? 127  THR C CA    1 
ATOM   7610  C C     . THR C 1 127 ? -1.033   -99.729  -6.360  1.00 30.27  ? 127  THR C C     1 
ATOM   7611  O O     . THR C 1 127 ? 0.174    -99.787  -6.501  1.00 32.12  ? 127  THR C O     1 
ATOM   7612  C CB    . THR C 1 127 ? -2.051   -99.993  -8.676  1.00 27.53  ? 127  THR C CB    1 
ATOM   7613  O OG1   . THR C 1 127 ? -2.521   -98.661  -8.490  1.00 28.04  ? 127  THR C OG1   1 
ATOM   7614  C CG2   . THR C 1 127 ? -2.995   -100.794 -9.552  1.00 26.45  ? 127  THR C CG2   1 
ATOM   7615  N N     . TYR C 1 128 ? -1.608   -98.965  -5.432  1.00 28.40  ? 128  TYR C N     1 
ATOM   7616  C CA    . TYR C 1 128 ? -0.850   -98.295  -4.397  1.00 30.23  ? 128  TYR C CA    1 
ATOM   7617  C C     . TYR C 1 128 ? -0.790   -99.224  -3.193  1.00 33.64  ? 128  TYR C C     1 
ATOM   7618  O O     . TYR C 1 128 ? -1.830   -99.546  -2.622  1.00 35.96  ? 128  TYR C O     1 
ATOM   7619  C CB    . TYR C 1 128 ? -1.624   -97.007  -4.109  1.00 28.74  ? 128  TYR C CB    1 
ATOM   7620  C CG    . TYR C 1 128 ? -1.159   -96.138  -2.956  1.00 31.25  ? 128  TYR C CG    1 
ATOM   7621  C CD1   . TYR C 1 128 ? 0.179    -96.087  -2.562  1.00 32.10  ? 128  TYR C CD1   1 
ATOM   7622  C CD2   . TYR C 1 128 ? -2.063   -95.325  -2.263  1.00 32.26  ? 128  TYR C CD2   1 
ATOM   7623  C CE1   . TYR C 1 128 ? 0.601    -95.263  -1.519  1.00 27.50  ? 128  TYR C CE1   1 
ATOM   7624  C CE2   . TYR C 1 128 ? -1.652   -94.497  -1.223  1.00 30.93  ? 128  TYR C CE2   1 
ATOM   7625  C CZ    . TYR C 1 128 ? -0.318   -94.470  -0.853  1.00 29.57  ? 128  TYR C CZ    1 
ATOM   7626  O OH    . TYR C 1 128 ? 0.075    -93.657  0.157   1.00 31.89  ? 128  TYR C OH    1 
ATOM   7627  N N     . ASP C 1 129 ? 0.419    -99.643  -2.803  1.00 30.38  ? 129  ASP C N     1 
ATOM   7628  C CA    . ASP C 1 129 ? 0.599    -100.762 -1.885  1.00 28.80  ? 129  ASP C CA    1 
ATOM   7629  C C     . ASP C 1 129 ? 1.444    -100.312 -0.692  1.00 31.66  ? 129  ASP C C     1 
ATOM   7630  O O     . ASP C 1 129 ? 2.496    -99.744  -0.886  1.00 34.75  ? 129  ASP C O     1 
ATOM   7631  C CB    . ASP C 1 129 ? 1.222    -101.931 -2.627  1.00 26.44  ? 129  ASP C CB    1 
ATOM   7632  C CG    . ASP C 1 129 ? 1.351    -103.237 -1.852  1.00 28.92  ? 129  ASP C CG    1 
ATOM   7633  O OD1   . ASP C 1 129 ? 1.902    -103.196 -0.717  1.00 28.95  ? 129  ASP C OD1   1 
ATOM   7634  O OD2   . ASP C 1 129 ? 0.935    -104.305 -2.407  1.00 31.33  ? 129  ASP C OD2   1 
ATOM   7635  N N     . TRP C 1 130 ? 0.977    -100.536 0.548   1.00 26.94  ? 130  TRP C N     1 
ATOM   7636  C CA    . TRP C 1 130 ? 1.678    -100.082 1.748   1.00 28.80  ? 130  TRP C CA    1 
ATOM   7637  C C     . TRP C 1 130 ? 2.506    -101.218 2.346   1.00 31.41  ? 130  TRP C C     1 
ATOM   7638  O O     . TRP C 1 130 ? 3.201    -101.001 3.342   1.00 27.11  ? 130  TRP C O     1 
ATOM   7639  C CB    . TRP C 1 130 ? 0.707    -99.589  2.831   1.00 24.96  ? 130  TRP C CB    1 
ATOM   7640  C CG    . TRP C 1 130 ? -0.211   -98.482  2.396   1.00 27.03  ? 130  TRP C CG    1 
ATOM   7641  C CD1   . TRP C 1 130 ? 0.030    -97.536  1.438   1.00 30.39  ? 130  TRP C CD1   1 
ATOM   7642  C CD2   . TRP C 1 130 ? -1.532   -98.206  2.915   1.00 27.02  ? 130  TRP C CD2   1 
ATOM   7643  N NE1   . TRP C 1 130 ? -1.054   -96.708  1.298   1.00 33.58  ? 130  TRP C NE1   1 
ATOM   7644  C CE2   . TRP C 1 130 ? -2.019   -97.079  2.204   1.00 29.50  ? 130  TRP C CE2   1 
ATOM   7645  C CE3   . TRP C 1 130 ? -2.338   -98.798  3.901   1.00 26.07  ? 130  TRP C CE3   1 
ATOM   7646  C CZ2   . TRP C 1 130 ? -3.278   -96.528  2.446   1.00 26.84  ? 130  TRP C CZ2   1 
ATOM   7647  C CZ3   . TRP C 1 130 ? -3.576   -98.238  4.152   1.00 29.35  ? 130  TRP C CZ3   1 
ATOM   7648  C CH2   . TRP C 1 130 ? -4.034   -97.132  3.424   1.00 25.51  ? 130  TRP C CH2   1 
ATOM   7649  N N     . HIS C 1 131 ? 2.385    -102.437 1.804   1.00 29.78  ? 131  HIS C N     1 
ATOM   7650  C CA    . HIS C 1 131 ? 3.056    -103.566 2.429   1.00 32.21  ? 131  HIS C CA    1 
ATOM   7651  C C     . HIS C 1 131 ? 4.496    -103.742 1.924   1.00 35.01  ? 131  HIS C C     1 
ATOM   7652  O O     . HIS C 1 131 ? 5.422    -103.841 2.723   1.00 29.63  ? 131  HIS C O     1 
ATOM   7653  C CB    . HIS C 1 131 ? 2.312    -104.867 2.161   1.00 28.71  ? 131  HIS C CB    1 
ATOM   7654  C CG    . HIS C 1 131 ? 3.069    -106.058 2.662   1.00 32.57  ? 131  HIS C CG    1 
ATOM   7655  N ND1   . HIS C 1 131 ? 3.320    -106.268 4.004   1.00 29.43  ? 131  HIS C ND1   1 
ATOM   7656  C CD2   . HIS C 1 131 ? 3.592    -107.119 2.018   1.00 29.39  ? 131  HIS C CD2   1 
ATOM   7657  C CE1   . HIS C 1 131 ? 3.955    -107.427 4.160   1.00 27.23  ? 131  HIS C CE1   1 
ATOM   7658  N NE2   . HIS C 1 131 ? 4.114    -107.965 2.970   1.00 29.99  ? 131  HIS C NE2   1 
ATOM   7659  N N     . THR C 1 132 ? 4.679    -103.828 0.605   1.00 31.83  ? 132  THR C N     1 
ATOM   7660  C CA    . THR C 1 132 ? 5.971    -104.176 0.041   1.00 36.40  ? 132  THR C CA    1 
ATOM   7661  C C     . THR C 1 132 ? 6.863    -102.933 0.002   1.00 32.89  ? 132  THR C C     1 
ATOM   7662  O O     . THR C 1 132 ? 6.483    -101.900 -0.543  1.00 30.81  ? 132  THR C O     1 
ATOM   7663  C CB    . THR C 1 132 ? 5.808    -104.811 -1.349  1.00 33.21  ? 132  THR C CB    1 
ATOM   7664  O OG1   . THR C 1 132 ? 7.132    -104.813 -1.869  1.00 34.46  ? 132  THR C OG1   1 
ATOM   7665  C CG2   . THR C 1 132 ? 4.977    -103.979 -2.307  1.00 28.62  ? 132  THR C CG2   1 
ATOM   7666  N N     . PRO C 1 133 ? 8.110    -103.016 0.520   1.00 33.70  ? 133  PRO C N     1 
ATOM   7667  C CA    . PRO C 1 133 ? 9.069    -101.911 0.378   1.00 28.76  ? 133  PRO C CA    1 
ATOM   7668  C C     . PRO C 1 133 ? 9.386    -101.561 -1.074  1.00 26.43  ? 133  PRO C C     1 
ATOM   7669  O O     . PRO C 1 133 ? 9.808    -100.441 -1.377  1.00 25.68  ? 133  PRO C O     1 
ATOM   7670  C CB    . PRO C 1 133 ? 10.275   -102.342 1.192   1.00 30.65  ? 133  PRO C CB    1 
ATOM   7671  C CG    . PRO C 1 133 ? 10.107   -103.852 1.395   1.00 33.37  ? 133  PRO C CG    1 
ATOM   7672  C CD    . PRO C 1 133 ? 8.641    -104.185 1.247   1.00 30.16  ? 133  PRO C CD    1 
ATOM   7673  N N     . LEU C 1 134 ? 9.092    -102.490 -2.001  1.00 25.46  ? 134  LEU C N     1 
ATOM   7674  C CA    . LEU C 1 134 ? 9.352    -102.219 -3.406  1.00 25.76  ? 134  LEU C CA    1 
ATOM   7675  C C     . LEU C 1 134 ? 8.620    -100.948 -3.830  1.00 30.92  ? 134  LEU C C     1 
ATOM   7676  O O     . LEU C 1 134 ? 9.124    -100.203 -4.670  1.00 30.60  ? 134  LEU C O     1 
ATOM   7677  C CB    . LEU C 1 134 ? 9.016    -103.395 -4.323  1.00 26.05  ? 134  LEU C CB    1 
ATOM   7678  C CG    . LEU C 1 134 ? 9.669    -104.746 -4.010  1.00 27.63  ? 134  LEU C CG    1 
ATOM   7679  C CD1   . LEU C 1 134 ? 9.120    -105.848 -4.901  1.00 24.52  ? 134  LEU C CD1   1 
ATOM   7680  C CD2   . LEU C 1 134 ? 11.187   -104.642 -4.151  1.00 26.07  ? 134  LEU C CD2   1 
ATOM   7681  N N     . TYR C 1 135 ? 7.430    -100.688 -3.269  1.00 29.60  ? 135  TYR C N     1 
ATOM   7682  C CA    . TYR C 1 135 ? 6.605    -99.594  -3.775  1.00 30.30  ? 135  TYR C CA    1 
ATOM   7683  C C     . TYR C 1 135 ? 7.364    -98.259  -3.741  1.00 31.94  ? 135  TYR C C     1 
ATOM   7684  O O     . TYR C 1 135 ? 7.350    -97.528  -4.729  1.00 33.97  ? 135  TYR C O     1 
ATOM   7685  C CB    . TYR C 1 135 ? 5.250    -99.547  -3.047  1.00 28.96  ? 135  TYR C CB    1 
ATOM   7686  C CG    . TYR C 1 135 ? 4.314    -98.506  -3.655  1.00 26.81  ? 135  TYR C CG    1 
ATOM   7687  C CD1   . TYR C 1 135 ? 3.552    -98.828  -4.782  1.00 24.33  ? 135  TYR C CD1   1 
ATOM   7688  C CD2   . TYR C 1 135 ? 4.252    -97.194  -3.154  1.00 22.75  ? 135  TYR C CD2   1 
ATOM   7689  C CE1   . TYR C 1 135 ? 2.776    -97.866  -5.406  1.00 23.00  ? 135  TYR C CE1   1 
ATOM   7690  C CE2   . TYR C 1 135 ? 3.495    -96.232  -3.798  1.00 23.64  ? 135  TYR C CE2   1 
ATOM   7691  C CZ    . TYR C 1 135 ? 2.733    -96.580  -4.903  1.00 27.35  ? 135  TYR C CZ    1 
ATOM   7692  O OH    . TYR C 1 135 ? 1.925    -95.659  -5.502  1.00 30.34  ? 135  TYR C OH    1 
ATOM   7693  N N     . ASP C 1 136 ? 8.008    -97.928  -2.605  1.00 35.99  ? 136  ASP C N     1 
ATOM   7694  C CA    . ASP C 1 136 ? 8.736    -96.663  -2.540  1.00 36.36  ? 136  ASP C CA    1 
ATOM   7695  C C     . ASP C 1 136 ? 10.207   -96.804  -2.932  1.00 38.27  ? 136  ASP C C     1 
ATOM   7696  O O     . ASP C 1 136 ? 10.787   -95.848  -3.425  1.00 38.27  ? 136  ASP C O     1 
ATOM   7697  C CB    . ASP C 1 136 ? 8.643    -95.996  -1.180  1.00 41.84  ? 136  ASP C CB    1 
ATOM   7698  C CG    . ASP C 1 136 ? 7.267    -95.437  -0.838  1.00 47.29  ? 136  ASP C CG    1 
ATOM   7699  O OD1   . ASP C 1 136 ? 6.638    -94.808  -1.742  1.00 42.78  ? 136  ASP C OD1   1 
ATOM   7700  O OD2   . ASP C 1 136 ? 6.865    -95.594  0.337   1.00 42.11  ? 136  ASP C OD2   1 
ATOM   7701  N N     . ASP C 1 137 ? 10.794   -97.986  -2.708  1.00 38.63  ? 137  ASP C N     1 
ATOM   7702  C CA    . ASP C 1 137 ? 12.241   -98.134  -2.739  1.00 42.24  ? 137  ASP C CA    1 
ATOM   7703  C C     . ASP C 1 137 ? 12.736   -98.676  -4.068  1.00 37.69  ? 137  ASP C C     1 
ATOM   7704  O O     . ASP C 1 137 ? 13.916   -98.544  -4.326  1.00 41.15  ? 137  ASP C O     1 
ATOM   7705  C CB    . ASP C 1 137 ? 12.684   -98.780  -1.444  1.00 40.97  ? 137  ASP C CB    1 
ATOM   7706  C CG    . ASP C 1 137 ? 12.308   -97.892  -0.248  1.00 44.82  ? 137  ASP C CG    1 
ATOM   7707  O OD1   . ASP C 1 137 ? 12.368   -96.621  -0.390  1.00 39.06  ? 137  ASP C OD1   1 
ATOM   7708  O OD2   . ASP C 1 137 ? 12.005   -98.429  0.854   1.00 44.93  ? 137  ASP C OD2   1 
ATOM   7709  N N     . ASP C 1 138 ? 11.863   -99.244  -4.910  1.00 38.42  ? 138  ASP C N     1 
ATOM   7710  C CA    . ASP C 1 138 ? 12.255   -99.830  -6.181  1.00 36.78  ? 138  ASP C CA    1 
ATOM   7711  C C     . ASP C 1 138 ? 11.028   -99.996  -7.088  1.00 38.86  ? 138  ASP C C     1 
ATOM   7712  O O     . ASP C 1 138 ? 10.555   -101.115 -7.359  1.00 39.17  ? 138  ASP C O     1 
ATOM   7713  C CB    . ASP C 1 138 ? 13.037   -101.114 -5.967  1.00 34.88  ? 138  ASP C CB    1 
ATOM   7714  C CG    . ASP C 1 138 ? 13.708   -101.707 -7.214  1.00 39.50  ? 138  ASP C CG    1 
ATOM   7715  O OD1   . ASP C 1 138 ? 13.595   -101.087 -8.326  1.00 39.25  ? 138  ASP C OD1   1 
ATOM   7716  O OD2   . ASP C 1 138 ? 14.304   -102.823 -7.074  1.00 43.27  ? 138  ASP C OD2   1 
ATOM   7717  N N     . PHE C 1 139 ? 10.538   -98.853  -7.580  1.00 38.08  ? 139  PHE C N     1 
ATOM   7718  C CA    . PHE C 1 139 ? 9.246    -98.813  -8.244  1.00 36.79  ? 139  PHE C CA    1 
ATOM   7719  C C     . PHE C 1 139 ? 9.221    -99.793  -9.422  1.00 44.78  ? 139  PHE C C     1 
ATOM   7720  O O     . PHE C 1 139 ? 8.238    -100.533 -9.583  1.00 45.69  ? 139  PHE C O     1 
ATOM   7721  C CB    . PHE C 1 139 ? 8.835    -97.371  -8.545  1.00 35.16  ? 139  PHE C CB    1 
ATOM   7722  C CG    . PHE C 1 139 ? 7.409    -97.288  -9.072  1.00 41.50  ? 139  PHE C CG    1 
ATOM   7723  C CD1   . PHE C 1 139 ? 6.322    -97.525  -8.231  1.00 42.93  ? 139  PHE C CD1   1 
ATOM   7724  C CD2   . PHE C 1 139 ? 7.153    -96.982  -10.412 1.00 41.65  ? 139  PHE C CD2   1 
ATOM   7725  C CE1   . PHE C 1 139 ? 5.033    -97.470  -8.707  1.00 41.27  ? 139  PHE C CE1   1 
ATOM   7726  C CE2   . PHE C 1 139 ? 5.850    -96.900  -10.887 1.00 35.88  ? 139  PHE C CE2   1 
ATOM   7727  C CZ    . PHE C 1 139 ? 4.800    -97.147  -10.029 1.00 38.49  ? 139  PHE C CZ    1 
ATOM   7728  N N     . PRO C 1 140 ? 10.266   -99.836  -10.295 1.00 43.79  ? 140  PRO C N     1 
ATOM   7729  C CA    . PRO C 1 140 ? 10.255   -100.772 -11.418 1.00 47.78  ? 140  PRO C CA    1 
ATOM   7730  C C     . PRO C 1 140 ? 10.029   -102.220 -10.985 1.00 38.44  ? 140  PRO C C     1 
ATOM   7731  O O     . PRO C 1 140 ? 9.290    -102.962 -11.634 1.00 43.15  ? 140  PRO C O     1 
ATOM   7732  C CB    . PRO C 1 140 ? 11.561   -100.467 -12.179 1.00 46.89  ? 140  PRO C CB    1 
ATOM   7733  C CG    . PRO C 1 140 ? 11.817   -99.006  -11.788 1.00 38.17  ? 140  PRO C CG    1 
ATOM   7734  C CD    . PRO C 1 140 ? 11.447   -98.960  -10.307 1.00 40.56  ? 140  PRO C CD    1 
ATOM   7735  N N     . ALA C 1 141 ? 10.655   -102.609 -9.866  1.00 36.44  ? 141  ALA C N     1 
ATOM   7736  C CA    . ALA C 1 141 ? 10.482   -103.963 -9.362  1.00 32.81  ? 141  ALA C CA    1 
ATOM   7737  C C     . ALA C 1 141 ? 9.082    -104.147 -8.756  1.00 36.63  ? 141  ALA C C     1 
ATOM   7738  O O     . ALA C 1 141 ? 8.533    -105.259 -8.756  1.00 33.45  ? 141  ALA C O     1 
ATOM   7739  C CB    . ALA C 1 141 ? 11.580   -104.272 -8.353  1.00 29.52  ? 141  ALA C CB    1 
ATOM   7740  N N     . TYR C 1 142 ? 8.513    -103.056 -8.208  1.00 32.77  ? 142  TYR C N     1 
ATOM   7741  C CA    . TYR C 1 142 ? 7.136    -103.056 -7.731  1.00 31.12  ? 142  TYR C CA    1 
ATOM   7742  C C     . TYR C 1 142 ? 6.186    -103.393 -8.888  1.00 29.66  ? 142  TYR C C     1 
ATOM   7743  O O     . TYR C 1 142 ? 5.309    -104.250 -8.738  1.00 29.12  ? 142  TYR C O     1 
ATOM   7744  C CB    . TYR C 1 142 ? 6.706    -101.810 -6.942  1.00 27.55  ? 142  TYR C CB    1 
ATOM   7745  C CG    . TYR C 1 142 ? 5.210    -101.874 -6.686  1.00 28.34  ? 142  TYR C CG    1 
ATOM   7746  C CD1   . TYR C 1 142 ? 4.689    -102.701 -5.694  1.00 27.44  ? 142  TYR C CD1   1 
ATOM   7747  C CD2   . TYR C 1 142 ? 4.314    -101.151 -7.481  1.00 30.89  ? 142  TYR C CD2   1 
ATOM   7748  C CE1   . TYR C 1 142 ? 3.327    -102.819 -5.485  1.00 31.28  ? 142  TYR C CE1   1 
ATOM   7749  C CE2   . TYR C 1 142 ? 2.947    -101.251 -7.280  1.00 31.73  ? 142  TYR C CE2   1 
ATOM   7750  C CZ    . TYR C 1 142 ? 2.456    -102.087 -6.285  1.00 36.09  ? 142  TYR C CZ    1 
ATOM   7751  O OH    . TYR C 1 142 ? 1.115    -102.170 -6.074  1.00 32.22  ? 142  TYR C OH    1 
ATOM   7752  N N     . LEU C 1 143 ? 6.393    -102.744 -10.047 1.00 26.97  ? 143  LEU C N     1 
ATOM   7753  C CA    . LEU C 1 143 ? 5.566    -103.020 -11.213 1.00 28.58  ? 143  LEU C CA    1 
ATOM   7754  C C     . LEU C 1 143 ? 5.581    -104.509 -11.569 1.00 30.71  ? 143  LEU C C     1 
ATOM   7755  O O     . LEU C 1 143 ? 4.551    -105.056 -11.950 1.00 35.92  ? 143  LEU C O     1 
ATOM   7756  C CB    . LEU C 1 143 ? 5.911    -102.148 -12.402 1.00 28.32  ? 143  LEU C CB    1 
ATOM   7757  C CG    . LEU C 1 143 ? 5.814    -100.645 -12.144 1.00 36.58  ? 143  LEU C CG    1 
ATOM   7758  C CD1   . LEU C 1 143 ? 6.230    -99.909  -13.397 1.00 33.35  ? 143  LEU C CD1   1 
ATOM   7759  C CD2   . LEU C 1 143 ? 4.404    -100.274 -11.731 1.00 36.04  ? 143  LEU C CD2   1 
ATOM   7760  N N     . THR C 1 144 ? 6.723    -105.179 -11.388 1.00 34.37  ? 144  THR C N     1 
ATOM   7761  C CA    . THR C 1 144 ? 6.834    -106.599 -11.705 1.00 34.07  ? 144  THR C CA    1 
ATOM   7762  C C     . THR C 1 144 ? 5.994    -107.406 -10.721 1.00 32.97  ? 144  THR C C     1 
ATOM   7763  O O     . THR C 1 144 ? 5.345    -108.390 -11.108 1.00 36.53  ? 144  THR C O     1 
ATOM   7764  C CB    . THR C 1 144 ? 8.311    -107.033 -11.703 1.00 35.10  ? 144  THR C CB    1 
ATOM   7765  O OG1   . THR C 1 144 ? 8.874    -106.275 -12.766 1.00 36.26  ? 144  THR C OG1   1 
ATOM   7766  C CG2   . THR C 1 144 ? 8.575    -108.514 -11.909 1.00 23.82  ? 144  THR C CG2   1 
ATOM   7767  N N     . TYR C 1 145 ? 6.051    -107.007 -9.442  1.00 31.51  ? 145  TYR C N     1 
ATOM   7768  C CA    . TYR C 1 145 ? 5.318    -107.689 -8.376  1.00 29.02  ? 145  TYR C CA    1 
ATOM   7769  C C     . TYR C 1 145 ? 3.806    -107.509 -8.589  1.00 29.68  ? 145  TYR C C     1 
ATOM   7770  O O     . TYR C 1 145 ? 3.032    -108.466 -8.514  1.00 31.09  ? 145  TYR C O     1 
ATOM   7771  C CB    . TYR C 1 145 ? 5.825    -107.029 -7.101  1.00 26.22  ? 145  TYR C CB    1 
ATOM   7772  C CG    . TYR C 1 145 ? 5.118    -107.393 -5.800  1.00 31.47  ? 145  TYR C CG    1 
ATOM   7773  C CD1   . TYR C 1 145 ? 5.548    -108.461 -5.011  1.00 29.04  ? 145  TYR C CD1   1 
ATOM   7774  C CD2   . TYR C 1 145 ? 4.049    -106.615 -5.328  1.00 27.50  ? 145  TYR C CD2   1 
ATOM   7775  C CE1   . TYR C 1 145 ? 4.929    -108.745 -3.803  1.00 30.72  ? 145  TYR C CE1   1 
ATOM   7776  C CE2   . TYR C 1 145 ? 3.422    -106.900 -4.126  1.00 27.47  ? 145  TYR C CE2   1 
ATOM   7777  C CZ    . TYR C 1 145 ? 3.866    -107.968 -3.364  1.00 27.95  ? 145  TYR C CZ    1 
ATOM   7778  O OH    . TYR C 1 145 ? 3.268    -108.211 -2.168  1.00 27.58  ? 145  TYR C OH    1 
ATOM   7779  N N     . LEU C 1 146 ? 3.395    -106.268 -8.888  1.00 29.78  ? 146  LEU C N     1 
ATOM   7780  C CA    . LEU C 1 146 ? 1.997    -105.972 -9.159  1.00 31.06  ? 146  LEU C CA    1 
ATOM   7781  C C     . LEU C 1 146 ? 1.514    -106.842 -10.324 1.00 31.32  ? 146  LEU C C     1 
ATOM   7782  O O     . LEU C 1 146 ? 0.521    -107.560 -10.208 1.00 28.83  ? 146  LEU C O     1 
ATOM   7783  C CB    . LEU C 1 146 ? 1.820    -104.478 -9.436  1.00 25.99  ? 146  LEU C CB    1 
ATOM   7784  C CG    . LEU C 1 146 ? 0.442    -104.050 -9.930  1.00 26.76  ? 146  LEU C CG    1 
ATOM   7785  C CD1   . LEU C 1 146 ? -0.680   -104.413 -8.932  1.00 23.82  ? 146  LEU C CD1   1 
ATOM   7786  C CD2   . LEU C 1 146 ? 0.475    -102.562 -10.252 1.00 22.63  ? 146  LEU C CD2   1 
ATOM   7787  N N     . GLN C 1 147 ? 2.293    -106.840 -11.409 1.00 35.09  ? 147  GLN C N     1 
ATOM   7788  C CA    . GLN C 1 147 ? 1.948    -107.591 -12.600 1.00 32.48  ? 147  GLN C CA    1 
ATOM   7789  C C     . GLN C 1 147 ? 1.844    -109.090 -12.315 1.00 31.02  ? 147  GLN C C     1 
ATOM   7790  O O     . GLN C 1 147 ? 0.924    -109.765 -12.794 1.00 36.11  ? 147  GLN C O     1 
ATOM   7791  C CB    . GLN C 1 147 ? 2.897    -107.281 -13.751 1.00 32.46  ? 147  GLN C CB    1 
ATOM   7792  C CG    . GLN C 1 147 ? 2.466    -108.017 -15.006 1.00 35.21  ? 147  GLN C CG    1 
ATOM   7793  C CD    . GLN C 1 147 ? 3.141    -107.510 -16.256 1.00 35.30  ? 147  GLN C CD    1 
ATOM   7794  O OE1   . GLN C 1 147 ? 3.294    -106.305 -16.501 1.00 39.86  ? 147  GLN C OE1   1 
ATOM   7795  N NE2   . GLN C 1 147 ? 3.524    -108.465 -17.081 1.00 35.73  ? 147  GLN C NE2   1 
ATOM   7796  N N     . LYS C 1 148 ? 2.759    -109.608 -11.501 1.00 31.27  ? 148  LYS C N     1 
ATOM   7797  C CA    . LYS C 1 148 ? 2.723    -111.022 -11.178 1.00 31.61  ? 148  LYS C CA    1 
ATOM   7798  C C     . LYS C 1 148 ? 1.466    -111.348 -10.359 1.00 34.23  ? 148  LYS C C     1 
ATOM   7799  O O     . LYS C 1 148 ? 0.835    -112.405 -10.549 1.00 34.02  ? 148  LYS C O     1 
ATOM   7800  C CB    . LYS C 1 148 ? 4.030    -111.365 -10.446 1.00 37.63  ? 148  LYS C CB    1 
ATOM   7801  C CG    . LYS C 1 148 ? 4.218    -112.863 -10.194 1.00 46.70  ? 148  LYS C CG    1 
ATOM   7802  C CD    . LYS C 1 148 ? 4.791    -113.472 -11.468 1.00 62.14  ? 148  LYS C CD    1 
ATOM   7803  C CE    . LYS C 1 148 ? 4.381    -114.867 -11.794 1.00 70.22  ? 148  LYS C CE    1 
ATOM   7804  N NZ    . LYS C 1 148 ? 5.134    -115.167 -13.014 1.00 72.61  ? 148  LYS C NZ    1 
ATOM   7805  N N     . SER C 1 149 ? 1.117    -110.449 -9.420  1.00 33.39  ? 149  SER C N     1 
ATOM   7806  C CA    . SER C 1 149 ? -0.047   -110.690 -8.568  1.00 31.45  ? 149  SER C CA    1 
ATOM   7807  C C     . SER C 1 149 ? -1.323   -110.712 -9.422  1.00 28.83  ? 149  SER C C     1 
ATOM   7808  O O     . SER C 1 149 ? -2.229   -111.496 -9.160  1.00 27.41  ? 149  SER C O     1 
ATOM   7809  C CB    . SER C 1 149 ? -0.136   -109.711 -7.410  1.00 30.64  ? 149  SER C CB    1 
ATOM   7810  O OG    . SER C 1 149 ? -0.563   -108.436 -7.885  1.00 27.22  ? 149  SER C OG    1 
ATOM   7811  N N     . VAL C 1 150 ? -1.353   -109.910 -10.496 1.00 26.56  ? 150  VAL C N     1 
ATOM   7812  C CA    . VAL C 1 150 ? -2.489   -109.921 -11.402 1.00 30.61  ? 150  VAL C CA    1 
ATOM   7813  C C     . VAL C 1 150 ? -2.482   -111.170 -12.289 1.00 38.33  ? 150  VAL C C     1 
ATOM   7814  O O     . VAL C 1 150 ? -3.544   -111.735 -12.606 1.00 35.74  ? 150  VAL C O     1 
ATOM   7815  C CB    . VAL C 1 150 ? -2.538   -108.619 -12.214 1.00 29.38  ? 150  VAL C CB    1 
ATOM   7816  C CG1   . VAL C 1 150 ? -3.607   -108.677 -13.294 1.00 26.23  ? 150  VAL C CG1   1 
ATOM   7817  C CG2   . VAL C 1 150 ? -2.732   -107.418 -11.300 1.00 29.66  ? 150  VAL C CG2   1 
ATOM   7818  N N     . GLU C 1 151 ? -1.273   -111.601 -12.670 1.00 40.15  ? 151  GLU C N     1 
ATOM   7819  C CA    . GLU C 1 151 ? -1.127   -112.799 -13.487 1.00 38.44  ? 151  GLU C CA    1 
ATOM   7820  C C     . GLU C 1 151 ? -1.701   -114.027 -12.770 1.00 31.77  ? 151  GLU C C     1 
ATOM   7821  O O     . GLU C 1 151 ? -2.390   -114.841 -13.393 1.00 30.86  ? 151  GLU C O     1 
ATOM   7822  C CB    . GLU C 1 151 ? 0.335    -112.947 -13.898 1.00 41.48  ? 151  GLU C CB    1 
ATOM   7823  C CG    . GLU C 1 151 ? 0.569    -114.149 -14.801 1.00 51.96  ? 151  GLU C CG    1 
ATOM   7824  C CD    . GLU C 1 151 ? 2.020    -114.452 -15.136 1.00 55.91  ? 151  GLU C CD    1 
ATOM   7825  O OE1   . GLU C 1 151 ? 2.966    -113.686 -14.802 1.00 54.20  ? 151  GLU C OE1   1 
ATOM   7826  O OE2   . GLU C 1 151 ? 2.201    -115.520 -15.728 1.00 60.35  ? 151  GLU C OE2   1 
ATOM   7827  N N     . VAL C 1 152 ? -1.441   -114.149 -11.463 1.00 28.44  ? 152  VAL C N     1 
ATOM   7828  C CA    . VAL C 1 152 ? -2.025   -115.247 -10.703 1.00 29.84  ? 152  VAL C CA    1 
ATOM   7829  C C     . VAL C 1 152 ? -3.555   -115.242 -10.830 1.00 36.50  ? 152  VAL C C     1 
ATOM   7830  O O     . VAL C 1 152 ? -4.167   -116.300 -10.996 1.00 37.84  ? 152  VAL C O     1 
ATOM   7831  C CB    . VAL C 1 152 ? -1.592   -115.206 -9.227  1.00 30.40  ? 152  VAL C CB    1 
ATOM   7832  C CG1   . VAL C 1 152 ? -2.369   -116.202 -8.356  1.00 30.56  ? 152  VAL C CG1   1 
ATOM   7833  C CG2   . VAL C 1 152 ? -0.086   -115.417 -9.111  1.00 32.13  ? 152  VAL C CG2   1 
ATOM   7834  N N     . LEU C 1 153 ? -4.168   -114.041 -10.737 1.00 35.30  ? 153  LEU C N     1 
ATOM   7835  C CA    . LEU C 1 153 ? -5.616   -113.932 -10.782 1.00 30.03  ? 153  LEU C CA    1 
ATOM   7836  C C     . LEU C 1 153 ? -6.101   -114.311 -12.179 1.00 30.98  ? 153  LEU C C     1 
ATOM   7837  O O     . LEU C 1 153 ? -7.199   -114.854 -12.302 1.00 30.63  ? 153  LEU C O     1 
ATOM   7838  C CB    . LEU C 1 153 ? -6.128   -112.556 -10.372 1.00 24.67  ? 153  LEU C CB    1 
ATOM   7839  C CG    . LEU C 1 153 ? -5.934   -112.206 -8.899  1.00 22.41  ? 153  LEU C CG    1 
ATOM   7840  C CD1   . LEU C 1 153 ? -6.121   -110.704 -8.695  1.00 18.19  ? 153  LEU C CD1   1 
ATOM   7841  C CD2   . LEU C 1 153 ? -6.829   -113.025 -8.002  1.00 20.52  ? 153  LEU C CD2   1 
ATOM   7842  N N     . CYS C 1 154 ? -5.286   -114.022 -13.211 1.00 28.98  ? 154  CYS C N     1 
ATOM   7843  C CA    . CYS C 1 154 ? -5.669   -114.305 -14.580 1.00 33.13  ? 154  CYS C CA    1 
ATOM   7844  C C     . CYS C 1 154 ? -5.514   -115.783 -14.961 1.00 37.37  ? 154  CYS C C     1 
ATOM   7845  O O     . CYS C 1 154 ? -6.000   -116.174 -16.022 1.00 32.24  ? 154  CYS C O     1 
ATOM   7846  C CB    . CYS C 1 154 ? -4.763   -113.579 -15.555 1.00 34.59  ? 154  CYS C CB    1 
ATOM   7847  S SG    . CYS C 1 154 ? -5.065   -111.801 -15.603 1.00 36.22  ? 154  CYS C SG    1 
ATOM   7848  N N     . ARG C 1 155 ? -4.844   -116.601 -14.126 1.00 36.45  ? 155  ARG C N     1 
ATOM   7849  C CA    . ARG C 1 155 ? -4.458   -117.934 -14.572 1.00 34.41  ? 155  ARG C CA    1 
ATOM   7850  C C     . ARG C 1 155 ? -5.016   -119.037 -13.680 1.00 38.13  ? 155  ARG C C     1 
ATOM   7851  O O     . ARG C 1 155 ? -4.947   -120.191 -14.072 1.00 44.80  ? 155  ARG C O     1 
ATOM   7852  C CB    . ARG C 1 155 ? -2.942   -118.131 -14.706 1.00 35.13  ? 155  ARG C CB    1 
ATOM   7853  C CG    . ARG C 1 155 ? -2.422   -117.189 -15.793 1.00 46.64  ? 155  ARG C CG    1 
ATOM   7854  C CD    . ARG C 1 155 ? -0.923   -117.232 -15.989 1.00 50.57  ? 155  ARG C CD    1 
ATOM   7855  N NE    . ARG C 1 155 ? -0.566   -118.584 -16.429 1.00 69.34  ? 155  ARG C NE    1 
ATOM   7856  C CZ    . ARG C 1 155 ? 0.648    -119.072 -16.548 1.00 65.78  ? 155  ARG C CZ    1 
ATOM   7857  N NH1   . ARG C 1 155 ? 1.689    -118.288 -16.367 1.00 61.89  ? 155  ARG C NH1   1 
ATOM   7858  N NH2   . ARG C 1 155 ? 0.788    -120.337 -16.866 1.00 61.39  ? 155  ARG C NH2   1 
ATOM   7859  N N     . ASN C 1 156 ? -5.561   -118.727 -12.495 1.00 36.04  ? 156  ASN C N     1 
ATOM   7860  C CA    . ASN C 1 156 ? -5.867   -119.803 -11.567 1.00 35.89  ? 156  ASN C CA    1 
ATOM   7861  C C     . ASN C 1 156 ? -7.354   -119.919 -11.232 1.00 37.83  ? 156  ASN C C     1 
ATOM   7862  O O     . ASN C 1 156 ? -7.701   -120.681 -10.335 1.00 33.99  ? 156  ASN C O     1 
ATOM   7863  C CB    . ASN C 1 156 ? -5.030   -119.705 -10.298 1.00 42.33  ? 156  ASN C CB    1 
ATOM   7864  C CG    . ASN C 1 156 ? -3.584   -120.029 -10.582 1.00 41.04  ? 156  ASN C CG    1 
ATOM   7865  O OD1   . ASN C 1 156 ? -3.196   -121.191 -10.517 1.00 45.57  ? 156  ASN C OD1   1 
ATOM   7866  N ND2   . ASN C 1 156 ? -2.783   -119.053 -10.970 1.00 34.27  ? 156  ASN C ND2   1 
ATOM   7867  N N     . TYR C 1 157 ? -8.230   -119.164 -11.913 1.00 37.42  ? 157  TYR C N     1 
ATOM   7868  C CA    . TYR C 1 157 ? -9.602   -119.048 -11.428 1.00 37.34  ? 157  TYR C CA    1 
ATOM   7869  C C     . TYR C 1 157 ? -10.624  -119.200 -12.553 1.00 38.69  ? 157  TYR C C     1 
ATOM   7870  O O     . TYR C 1 157 ? -11.804  -118.989 -12.321 1.00 43.64  ? 157  TYR C O     1 
ATOM   7871  C CB    . TYR C 1 157 ? -9.769   -117.720 -10.662 1.00 32.08  ? 157  TYR C CB    1 
ATOM   7872  C CG    . TYR C 1 157 ? -8.824   -117.675 -9.472  1.00 32.04  ? 157  TYR C CG    1 
ATOM   7873  C CD1   . TYR C 1 157 ? -9.100   -118.413 -8.329  1.00 31.42  ? 157  TYR C CD1   1 
ATOM   7874  C CD2   . TYR C 1 157 ? -7.625   -116.962 -9.521  1.00 31.13  ? 157  TYR C CD2   1 
ATOM   7875  C CE1   . TYR C 1 157 ? -8.237   -118.416 -7.248  1.00 31.65  ? 157  TYR C CE1   1 
ATOM   7876  C CE2   . TYR C 1 157 ? -6.738   -116.985 -8.454  1.00 29.97  ? 157  TYR C CE2   1 
ATOM   7877  C CZ    . TYR C 1 157 ? -7.046   -117.714 -7.321  1.00 30.92  ? 157  TYR C CZ    1 
ATOM   7878  O OH    . TYR C 1 157 ? -6.202   -117.749 -6.242  1.00 30.09  ? 157  TYR C OH    1 
ATOM   7879  N N     . GLY C 1 158 ? -10.178  -119.564 -13.756 1.00 35.91  ? 158  GLY C N     1 
ATOM   7880  C CA    . GLY C 1 158 ? -11.052  -119.671 -14.905 1.00 34.18  ? 158  GLY C CA    1 
ATOM   7881  C C     . GLY C 1 158 ? -11.337  -118.291 -15.492 1.00 42.13  ? 158  GLY C C     1 
ATOM   7882  O O     . GLY C 1 158 ? -10.633  -117.326 -15.165 1.00 35.37  ? 158  GLY C O     1 
ATOM   7883  N N     . PRO C 1 159 ? -12.381  -118.148 -16.360 1.00 46.06  ? 159  PRO C N     1 
ATOM   7884  C CA    . PRO C 1 159 ? -12.729  -116.842 -16.933 1.00 44.38  ? 159  PRO C CA    1 
ATOM   7885  C C     . PRO C 1 159 ? -13.144  -115.829 -15.864 1.00 41.24  ? 159  PRO C C     1 
ATOM   7886  O O     . PRO C 1 159 ? -13.912  -116.145 -14.957 1.00 38.34  ? 159  PRO C O     1 
ATOM   7887  C CB    . PRO C 1 159 ? -13.872  -117.126 -17.914 1.00 36.73  ? 159  PRO C CB    1 
ATOM   7888  C CG    . PRO C 1 159 ? -14.031  -118.634 -17.935 1.00 47.92  ? 159  PRO C CG    1 
ATOM   7889  C CD    . PRO C 1 159 ? -13.284  -119.237 -16.774 1.00 44.74  ? 159  PRO C CD    1 
ATOM   7890  N N     . VAL C 1 160 ? -12.611  -114.613 -15.955 1.00 39.14  ? 160  VAL C N     1 
ATOM   7891  C CA    . VAL C 1 160 ? -12.829  -113.605 -14.932 1.00 38.27  ? 160  VAL C CA    1 
ATOM   7892  C C     . VAL C 1 160 ? -13.689  -112.521 -15.563 1.00 36.15  ? 160  VAL C C     1 
ATOM   7893  O O     . VAL C 1 160 ? -13.444  -112.116 -16.696 1.00 37.26  ? 160  VAL C O     1 
ATOM   7894  C CB    . VAL C 1 160 ? -11.414  -113.104 -14.577 1.00 39.55  ? 160  VAL C CB    1 
ATOM   7895  C CG1   . VAL C 1 160 ? -11.421  -111.846 -13.720 1.00 40.26  ? 160  VAL C CG1   1 
ATOM   7896  C CG2   . VAL C 1 160 ? -10.606  -114.167 -13.854 1.00 40.49  ? 160  VAL C CG2   1 
ATOM   7897  N N     . GLY C 1 161 ? -14.710  -112.044 -14.837 1.00 34.57  ? 161  GLY C N     1 
ATOM   7898  C CA    . GLY C 1 161 ? -15.559  -111.007 -15.402 1.00 29.01  ? 161  GLY C CA    1 
ATOM   7899  C C     . GLY C 1 161 ? -14.771  -109.723 -15.679 1.00 27.76  ? 161  GLY C C     1 
ATOM   7900  O O     . GLY C 1 161 ? -14.921  -109.097 -16.724 1.00 33.41  ? 161  GLY C O     1 
ATOM   7901  N N     . GLY C 1 162 ? -13.898  -109.340 -14.745 1.00 27.15  ? 162  GLY C N     1 
ATOM   7902  C CA    . GLY C 1 162 ? -13.197  -108.076 -14.896 1.00 24.98  ? 162  GLY C CA    1 
ATOM   7903  C C     . GLY C 1 162 ? -12.246  -107.799 -13.740 1.00 28.45  ? 162  GLY C C     1 
ATOM   7904  O O     . GLY C 1 162 ? -12.213  -108.532 -12.748 1.00 29.45  ? 162  GLY C O     1 
ATOM   7905  N N     . PHE C 1 163 ? -11.450  -106.747 -13.922 1.00 27.46  ? 163  PHE C N     1 
ATOM   7906  C CA    . PHE C 1 163 ? -10.484  -106.253 -12.963 1.00 28.37  ? 163  PHE C CA    1 
ATOM   7907  C C     . PHE C 1 163 ? -10.835  -104.788 -12.736 1.00 30.90  ? 163  PHE C C     1 
ATOM   7908  O O     . PHE C 1 163 ? -11.205  -104.065 -13.684 1.00 28.63  ? 163  PHE C O     1 
ATOM   7909  C CB    . PHE C 1 163 ? -9.082   -106.307 -13.581 1.00 25.47  ? 163  PHE C CB    1 
ATOM   7910  C CG    . PHE C 1 163 ? -8.556   -107.732 -13.634 1.00 30.98  ? 163  PHE C CG    1 
ATOM   7911  C CD1   . PHE C 1 163 ? -7.846   -108.273 -12.551 1.00 30.12  ? 163  PHE C CD1   1 
ATOM   7912  C CD2   . PHE C 1 163 ? -8.811   -108.545 -14.743 1.00 30.10  ? 163  PHE C CD2   1 
ATOM   7913  C CE1   . PHE C 1 163 ? -7.374   -109.586 -12.591 1.00 33.08  ? 163  PHE C CE1   1 
ATOM   7914  C CE2   . PHE C 1 163 ? -8.351   -109.861 -14.763 1.00 31.40  ? 163  PHE C CE2   1 
ATOM   7915  C CZ    . PHE C 1 163 ? -7.631   -110.378 -13.686 1.00 31.71  ? 163  PHE C CZ    1 
ATOM   7916  N N     . TRP C 1 164 ? -10.682  -104.382 -11.480 1.00 27.72  ? 164  TRP C N     1 
ATOM   7917  C CA    . TRP C 1 164 ? -11.008  -103.032 -11.056 1.00 27.69  ? 164  TRP C CA    1 
ATOM   7918  C C     . TRP C 1 164 ? -9.754   -102.477 -10.376 1.00 28.32  ? 164  TRP C C     1 
ATOM   7919  O O     . TRP C 1 164 ? -9.409   -102.872 -9.263  1.00 29.88  ? 164  TRP C O     1 
ATOM   7920  C CB    . TRP C 1 164 ? -12.212  -103.137 -10.107 1.00 24.57  ? 164  TRP C CB    1 
ATOM   7921  C CG    . TRP C 1 164 ? -13.126  -101.943 -10.026 1.00 25.65  ? 164  TRP C CG    1 
ATOM   7922  C CD1   . TRP C 1 164 ? -14.348  -101.807 -10.623 1.00 25.54  ? 164  TRP C CD1   1 
ATOM   7923  C CD2   . TRP C 1 164 ? -12.923  -100.740 -9.238  1.00 25.98  ? 164  TRP C CD2   1 
ATOM   7924  N NE1   . TRP C 1 164 ? -14.910  -100.600 -10.283 1.00 25.35  ? 164  TRP C NE1   1 
ATOM   7925  C CE2   . TRP C 1 164 ? -14.076  -99.928  -9.426  1.00 25.43  ? 164  TRP C CE2   1 
ATOM   7926  C CE3   . TRP C 1 164 ? -11.890  -100.262 -8.411  1.00 23.66  ? 164  TRP C CE3   1 
ATOM   7927  C CZ2   . TRP C 1 164 ? -14.211  -98.671  -8.829  1.00 27.88  ? 164  TRP C CZ2   1 
ATOM   7928  C CZ3   . TRP C 1 164 ? -12.049  -99.038  -7.791  1.00 27.80  ? 164  TRP C CZ3   1 
ATOM   7929  C CH2   . TRP C 1 164 ? -13.197  -98.259  -7.989  1.00 28.38  ? 164  TRP C CH2   1 
ATOM   7930  N N     . PHE C 1 165 ? -9.034   -101.625 -11.102 1.00 27.04  ? 165  PHE C N     1 
ATOM   7931  C CA    . PHE C 1 165 ? -7.717   -101.179 -10.683 1.00 29.22  ? 165  PHE C CA    1 
ATOM   7932  C C     . PHE C 1 165 ? -7.845   -99.820  -10.005 1.00 29.48  ? 165  PHE C C     1 
ATOM   7933  O O     . PHE C 1 165 ? -8.419   -98.880  -10.556 1.00 22.85  ? 165  PHE C O     1 
ATOM   7934  C CB    . PHE C 1 165 ? -6.695   -101.052 -11.824 1.00 26.83  ? 165  PHE C CB    1 
ATOM   7935  C CG    . PHE C 1 165 ? -6.259   -102.425 -12.283 1.00 29.14  ? 165  PHE C CG    1 
ATOM   7936  C CD1   . PHE C 1 165 ? -5.481   -103.231 -11.453 1.00 30.43  ? 165  PHE C CD1   1 
ATOM   7937  C CD2   . PHE C 1 165 ? -6.631   -102.922 -13.542 1.00 26.98  ? 165  PHE C CD2   1 
ATOM   7938  C CE1   . PHE C 1 165 ? -5.105   -104.516 -11.857 1.00 29.88  ? 165  PHE C CE1   1 
ATOM   7939  C CE2   . PHE C 1 165 ? -6.220   -104.195 -13.950 1.00 25.91  ? 165  PHE C CE2   1 
ATOM   7940  C CZ    . PHE C 1 165 ? -5.471   -104.990 -13.095 1.00 27.83  ? 165  PHE C CZ    1 
ATOM   7941  N N     . ASP C 1 166 ? -7.230   -99.719  -8.827  1.00 30.56  ? 166  ASP C N     1 
ATOM   7942  C CA    . ASP C 1 166 ? -7.336   -98.484  -8.085  1.00 28.01  ? 166  ASP C CA    1 
ATOM   7943  C C     . ASP C 1 166 ? -5.969   -98.053  -7.566  1.00 28.58  ? 166  ASP C C     1 
ATOM   7944  O O     . ASP C 1 166 ? -5.349   -98.782  -6.790  1.00 27.40  ? 166  ASP C O     1 
ATOM   7945  C CB    . ASP C 1 166 ? -8.295   -98.720  -6.942  1.00 30.20  ? 166  ASP C CB    1 
ATOM   7946  C CG    . ASP C 1 166 ? -8.368   -97.589  -5.935  1.00 31.86  ? 166  ASP C CG    1 
ATOM   7947  O OD1   . ASP C 1 166 ? -8.402   -96.436  -6.378  1.00 31.98  ? 166  ASP C OD1   1 
ATOM   7948  O OD2   . ASP C 1 166 ? -8.387   -97.876  -4.729  1.00 34.04  ? 166  ASP C OD2   1 
ATOM   7949  N N     . GLY C 1 167 ? -5.504   -96.853  -7.954  1.00 31.56  ? 167  GLY C N     1 
ATOM   7950  C CA    . GLY C 1 167 ? -4.432   -96.281  -7.135  1.00 37.15  ? 167  GLY C CA    1 
ATOM   7951  C C     . GLY C 1 167 ? -3.250   -95.695  -7.917  1.00 43.40  ? 167  GLY C C     1 
ATOM   7952  O O     . GLY C 1 167 ? -2.274   -95.229  -7.321  1.00 44.62  ? 167  GLY C O     1 
ATOM   7953  N N     . ASN C 1 168 ? -3.335   -95.715  -9.251  1.00 40.14  ? 168  ASN C N     1 
ATOM   7954  C CA    . ASN C 1 168 ? -2.336   -95.079  -10.094 1.00 38.77  ? 168  ASN C CA    1 
ATOM   7955  C C     . ASN C 1 168 ? -2.275   -93.579  -9.785  1.00 43.84  ? 168  ASN C C     1 
ATOM   7956  O O     . ASN C 1 168 ? -1.237   -92.950  -9.984  1.00 36.02  ? 168  ASN C O     1 
ATOM   7957  C CB    . ASN C 1 168 ? -2.531   -95.358  -11.584 1.00 34.34  ? 168  ASN C CB    1 
ATOM   7958  C CG    . ASN C 1 168 ? -2.281   -96.797  -11.992 1.00 35.00  ? 168  ASN C CG    1 
ATOM   7959  O OD1   . ASN C 1 168 ? -2.126   -97.081  -13.182 1.00 42.37  ? 168  ASN C OD1   1 
ATOM   7960  N ND2   . ASN C 1 168 ? -2.241   -97.739  -11.058 1.00 30.41  ? 168  ASN C ND2   1 
ATOM   7961  N N     . TRP C 1 169 ? -3.392   -93.027  -9.275  1.00 44.44  ? 169  TRP C N     1 
ATOM   7962  C CA    . TRP C 1 169 ? -3.520   -91.630  -8.862  1.00 43.58  ? 169  TRP C CA    1 
ATOM   7963  C C     . TRP C 1 169 ? -2.494   -91.259  -7.784  1.00 46.89  ? 169  TRP C C     1 
ATOM   7964  O O     . TRP C 1 169 ? -2.262   -90.066  -7.570  1.00 46.89  ? 169  TRP C O     1 
ATOM   7965  C CB    . TRP C 1 169 ? -4.954   -91.313  -8.383  1.00 37.10  ? 169  TRP C CB    1 
ATOM   7966  C CG    . TRP C 1 169 ? -5.540   -92.405  -7.512  1.00 39.47  ? 169  TRP C CG    1 
ATOM   7967  C CD1   . TRP C 1 169 ? -6.428   -93.373  -7.889  1.00 38.09  ? 169  TRP C CD1   1 
ATOM   7968  C CD2   . TRP C 1 169 ? -5.230   -92.665  -6.117  1.00 35.94  ? 169  TRP C CD2   1 
ATOM   7969  N NE1   . TRP C 1 169 ? -6.708   -94.197  -6.832  1.00 35.00  ? 169  TRP C NE1   1 
ATOM   7970  C CE2   . TRP C 1 169 ? -5.997   -93.794  -5.731  1.00 36.43  ? 169  TRP C CE2   1 
ATOM   7971  C CE3   . TRP C 1 169 ? -4.405   -92.039  -5.166  1.00 33.76  ? 169  TRP C CE3   1 
ATOM   7972  C CZ2   . TRP C 1 169 ? -5.975   -94.312  -4.436  1.00 31.98  ? 169  TRP C CZ2   1 
ATOM   7973  C CZ3   . TRP C 1 169 ? -4.356   -92.556  -3.889  1.00 39.88  ? 169  TRP C CZ3   1 
ATOM   7974  C CH2   . TRP C 1 169 ? -5.131   -93.689  -3.546  1.00 38.59  ? 169  TRP C CH2   1 
ATOM   7975  N N     . ASN C 1 170 ? -1.889   -92.263  -7.109  1.00 40.70  ? 170  ASN C N     1 
ATOM   7976  C CA    . ASN C 1 170 ? -0.907   -91.980  -6.081  1.00 38.02  ? 170  ASN C CA    1 
ATOM   7977  C C     . ASN C 1 170 ? 0.388    -91.417  -6.693  1.00 41.12  ? 170  ASN C C     1 
ATOM   7978  O O     . ASN C 1 170 ? 1.089    -90.651  -6.052  1.00 37.40  ? 170  ASN C O     1 
ATOM   7979  C CB    . ASN C 1 170 ? -0.657   -93.182  -5.176  1.00 39.44  ? 170  ASN C CB    1 
ATOM   7980  C CG    . ASN C 1 170 ? 0.470    -92.891  -4.208  1.00 41.41  ? 170  ASN C CG    1 
ATOM   7981  O OD1   . ASN C 1 170 ? 0.252    -92.127  -3.267  1.00 39.20  ? 170  ASN C OD1   1 
ATOM   7982  N ND2   . ASN C 1 170 ? 1.662    -93.453  -4.403  1.00 34.10  ? 170  ASN C ND2   1 
ATOM   7983  N N     . LYS C 1 171 ? 0.752    -91.850  -7.900  1.00 43.69  ? 171  LYS C N     1 
ATOM   7984  C CA    . LYS C 1 171 ? 1.906    -91.320  -8.628  1.00 48.49  ? 171  LYS C CA    1 
ATOM   7985  C C     . LYS C 1 171 ? 1.458    -90.961  -10.050 1.00 48.39  ? 171  LYS C C     1 
ATOM   7986  O O     . LYS C 1 171 ? 1.615    -91.781  -10.967 1.00 40.73  ? 171  LYS C O     1 
ATOM   7987  C CB    . LYS C 1 171 ? 3.018    -92.384  -8.703  1.00 40.83  ? 171  LYS C CB    1 
ATOM   7988  C CG    . LYS C 1 171 ? 3.672    -92.792  -7.396  1.00 44.70  ? 171  LYS C CG    1 
ATOM   7989  C CD    . LYS C 1 171 ? 4.764    -93.851  -7.480  1.00 51.63  ? 171  LYS C CD    1 
ATOM   7990  C CE    . LYS C 1 171 ? 5.546    -93.616  -6.226  1.00 66.08  ? 171  LYS C CE    1 
ATOM   7991  N NZ    . LYS C 1 171 ? 6.533    -94.635  -5.864  1.00 73.81  ? 171  LYS C NZ    1 
ATOM   7992  N N     . LYS C 1 172 ? 0.870    -89.765  -10.228 1.00 52.53  ? 172  LYS C N     1 
ATOM   7993  C CA    . LYS C 1 172 ? 0.228    -89.391  -11.489 1.00 65.60  ? 172  LYS C CA    1 
ATOM   7994  C C     . LYS C 1 172 ? 1.237    -89.337  -12.641 1.00 65.80  ? 172  LYS C C     1 
ATOM   7995  O O     . LYS C 1 172 ? 0.881    -89.529  -13.804 1.00 59.14  ? 172  LYS C O     1 
ATOM   7996  C CB    . LYS C 1 172 ? -0.585   -88.083  -11.451 1.00 58.42  ? 172  LYS C CB    1 
ATOM   7997  C CG    . LYS C 1 172 ? -1.783   -88.077  -10.527 1.00 73.78  ? 172  LYS C CG    1 
ATOM   7998  C CD    . LYS C 1 172 ? -2.992   -87.241  -10.969 1.00 90.31  ? 172  LYS C CD    1 
ATOM   7999  C CE    . LYS C 1 172 ? -4.260   -87.670  -10.271 1.00 82.21  ? 172  LYS C CE    1 
ATOM   8000  N NZ    . LYS C 1 172 ? -4.128   -87.382  -8.839  1.00 64.39  ? 172  LYS C NZ    1 
ATOM   8001  N N     . ASP C 1 173 ? 2.506    -89.064  -12.296 1.00 69.59  ? 173  ASP C N     1 
ATOM   8002  C CA    . ASP C 1 173 ? 3.556    -88.771  -13.261 1.00 69.29  ? 173  ASP C CA    1 
ATOM   8003  C C     . ASP C 1 173 ? 4.366    -90.006  -13.657 1.00 67.44  ? 173  ASP C C     1 
ATOM   8004  O O     . ASP C 1 173 ? 5.045    -89.969  -14.674 1.00 70.52  ? 173  ASP C O     1 
ATOM   8005  C CB    . ASP C 1 173 ? 4.363    -87.562  -12.811 1.00 71.18  ? 173  ASP C CB    1 
ATOM   8006  C CG    . ASP C 1 173 ? 3.602    -86.244  -12.940 1.00 74.58  ? 173  ASP C CG    1 
ATOM   8007  O OD1   . ASP C 1 173 ? 2.558    -86.198  -13.647 1.00 71.05  ? 173  ASP C OD1   1 
ATOM   8008  O OD2   . ASP C 1 173 ? 4.026    -85.278  -12.307 1.00 70.44  ? 173  ASP C OD2   1 
ATOM   8009  N N     . ALA C 1 174 ? 4.295    -91.101  -12.886 1.00 58.53  ? 174  ALA C N     1 
ATOM   8010  C CA    . ALA C 1 174 ? 5.152    -92.259  -13.093 1.00 45.58  ? 174  ALA C CA    1 
ATOM   8011  C C     . ALA C 1 174 ? 4.721    -93.043  -14.334 1.00 47.07  ? 174  ALA C C     1 
ATOM   8012  O O     . ALA C 1 174 ? 3.583    -92.938  -14.787 1.00 48.71  ? 174  ALA C O     1 
ATOM   8013  C CB    . ALA C 1 174 ? 5.131    -93.143  -11.872 1.00 36.69  ? 174  ALA C CB    1 
ATOM   8014  N N     . ASP C 1 175 ? 5.659    -93.823  -14.882 1.00 40.41  ? 175  ASP C N     1 
ATOM   8015  C CA    . ASP C 1 175 ? 5.339    -94.761  -15.937 1.00 38.34  ? 175  ASP C CA    1 
ATOM   8016  C C     . ASP C 1 175 ? 4.895    -96.061  -15.275 1.00 37.69  ? 175  ASP C C     1 
ATOM   8017  O O     . ASP C 1 175 ? 5.708    -96.734  -14.643 1.00 37.97  ? 175  ASP C O     1 
ATOM   8018  C CB    . ASP C 1 175 ? 6.511    -94.925  -16.890 1.00 43.54  ? 175  ASP C CB    1 
ATOM   8019  C CG    . ASP C 1 175 ? 6.307    -95.848  -18.090 1.00 56.20  ? 175  ASP C CG    1 
ATOM   8020  O OD1   . ASP C 1 175 ? 5.252    -96.523  -18.170 1.00 56.45  ? 175  ASP C OD1   1 
ATOM   8021  O OD2   . ASP C 1 175 ? 7.206    -95.864  -18.962 1.00 63.67  ? 175  ASP C OD2   1 
ATOM   8022  N N     . TRP C 1 176 ? 3.608    -96.412  -15.446 1.00 35.45  ? 176  TRP C N     1 
ATOM   8023  C CA    . TRP C 1 176 ? 3.044    -97.592  -14.798 1.00 34.19  ? 176  TRP C CA    1 
ATOM   8024  C C     . TRP C 1 176 ? 3.122    -98.830  -15.687 1.00 35.13  ? 176  TRP C C     1 
ATOM   8025  O O     . TRP C 1 176 ? 2.686    -99.910  -15.270 1.00 34.23  ? 176  TRP C O     1 
ATOM   8026  C CB    . TRP C 1 176 ? 1.599    -97.347  -14.344 1.00 32.17  ? 176  TRP C CB    1 
ATOM   8027  C CG    . TRP C 1 176 ? 1.479    -96.511  -13.103 1.00 30.81  ? 176  TRP C CG    1 
ATOM   8028  C CD1   . TRP C 1 176 ? 1.416    -95.144  -13.023 1.00 32.91  ? 176  TRP C CD1   1 
ATOM   8029  C CD2   . TRP C 1 176 ? 1.382    -97.000  -11.753 1.00 26.99  ? 176  TRP C CD2   1 
ATOM   8030  N NE1   . TRP C 1 176 ? 1.331    -94.744  -11.714 1.00 30.01  ? 176  TRP C NE1   1 
ATOM   8031  C CE2   . TRP C 1 176 ? 1.291    -95.862  -10.912 1.00 28.34  ? 176  TRP C CE2   1 
ATOM   8032  C CE3   . TRP C 1 176 ? 1.362    -98.280  -11.178 1.00 29.61  ? 176  TRP C CE3   1 
ATOM   8033  C CZ2   . TRP C 1 176 ? 1.181    -95.971  -9.529  1.00 25.91  ? 176  TRP C CZ2   1 
ATOM   8034  C CZ3   . TRP C 1 176 ? 1.243    -98.389  -9.806  1.00 27.69  ? 176  TRP C CZ3   1 
ATOM   8035  C CH2   . TRP C 1 176 ? 1.144    -97.246  -9.003  1.00 26.61  ? 176  TRP C CH2   1 
ATOM   8036  N N     . HIS C 1 177 ? 3.636    -98.671  -16.916 1.00 36.12  ? 177  HIS C N     1 
ATOM   8037  C CA    . HIS C 1 177 ? 3.826    -99.808  -17.812 1.00 36.60  ? 177  HIS C CA    1 
ATOM   8038  C C     . HIS C 1 177 ? 2.485    -100.513 -18.026 1.00 34.98  ? 177  HIS C C     1 
ATOM   8039  O O     . HIS C 1 177 ? 2.359    -101.745 -17.898 1.00 33.59  ? 177  HIS C O     1 
ATOM   8040  C CB    . HIS C 1 177 ? 4.975    -100.724 -17.343 1.00 39.84  ? 177  HIS C CB    1 
ATOM   8041  C CG    . HIS C 1 177 ? 6.348    -100.108 -17.486 1.00 55.06  ? 177  HIS C CG    1 
ATOM   8042  N ND1   . HIS C 1 177 ? 7.144    -100.141 -18.611 1.00 54.66  ? 177  HIS C ND1   1 
ATOM   8043  C CD2   . HIS C 1 177 ? 7.032    -99.373  -16.588 1.00 55.07  ? 177  HIS C CD2   1 
ATOM   8044  C CE1   . HIS C 1 177 ? 8.236    -99.424  -18.395 1.00 55.36  ? 177  HIS C CE1   1 
ATOM   8045  N NE2   . HIS C 1 177 ? 8.200    -98.972  -17.163 1.00 52.08  ? 177  HIS C NE2   1 
ATOM   8046  N N     . LEU C 1 178 ? 1.482    -99.706  -18.379 1.00 32.95  ? 178  LEU C N     1 
ATOM   8047  C CA    . LEU C 1 178 ? 0.125    -100.219 -18.562 1.00 34.49  ? 178  LEU C CA    1 
ATOM   8048  C C     . LEU C 1 178 ? 0.054    -101.131 -19.791 1.00 35.25  ? 178  LEU C C     1 
ATOM   8049  O O     . LEU C 1 178 ? -0.632   -102.160 -19.728 1.00 38.83  ? 178  LEU C O     1 
ATOM   8050  C CB    . LEU C 1 178 ? -0.912   -99.093  -18.584 1.00 32.59  ? 178  LEU C CB    1 
ATOM   8051  C CG    . LEU C 1 178 ? -0.952   -98.235  -17.316 1.00 38.22  ? 178  LEU C CG    1 
ATOM   8052  C CD1   . LEU C 1 178 ? -1.808   -96.981  -17.447 1.00 30.17  ? 178  LEU C CD1   1 
ATOM   8053  C CD2   . LEU C 1 178 ? -1.324   -99.105  -16.123 1.00 31.78  ? 178  LEU C CD2   1 
ATOM   8054  N N     . PRO C 1 179 ? 0.728    -100.810 -20.934 1.00 34.28  ? 179  PRO C N     1 
ATOM   8055  C CA    . PRO C 1 179 ? 0.744    -101.718 -22.084 1.00 32.54  ? 179  PRO C CA    1 
ATOM   8056  C C     . PRO C 1 179 ? 1.080    -103.158 -21.709 1.00 34.79  ? 179  PRO C C     1 
ATOM   8057  O O     . PRO C 1 179 ? 0.394    -104.093 -22.146 1.00 31.56  ? 179  PRO C O     1 
ATOM   8058  C CB    . PRO C 1 179 ? 1.646    -101.033 -23.118 1.00 29.66  ? 179  PRO C CB    1 
ATOM   8059  C CG    . PRO C 1 179 ? 1.543    -99.551  -22.725 1.00 29.43  ? 179  PRO C CG    1 
ATOM   8060  C CD    . PRO C 1 179 ? 1.424    -99.535  -21.215 1.00 32.39  ? 179  PRO C CD    1 
ATOM   8061  N N     . GLU C 1 180 ? 2.075    -103.314 -20.821 1.00 36.80  ? 180  GLU C N     1 
ATOM   8062  C CA    . GLU C 1 180 ? 2.510    -104.645 -20.424 1.00 40.04  ? 180  GLU C CA    1 
ATOM   8063  C C     . GLU C 1 180 ? 1.513    -105.290 -19.459 1.00 42.26  ? 180  GLU C C     1 
ATOM   8064  O O     . GLU C 1 180 ? 1.219    -106.480 -19.591 1.00 39.92  ? 180  GLU C O     1 
ATOM   8065  C CB    . GLU C 1 180 ? 3.977    -104.840 -20.014 1.00 47.17  ? 180  GLU C CB    1 
ATOM   8066  C CG    . GLU C 1 180 ? 4.782    -103.635 -19.547 1.00 66.85  ? 180  GLU C CG    1 
ATOM   8067  C CD    . GLU C 1 180 ? 5.336    -102.633 -20.535 1.00 59.95  ? 180  GLU C CD    1 
ATOM   8068  O OE1   . GLU C 1 180 ? 4.600    -101.654 -20.827 1.00 51.45  ? 180  GLU C OE1   1 
ATOM   8069  O OE2   . GLU C 1 180 ? 6.537    -102.781 -20.849 1.00 64.83  ? 180  GLU C OE2   1 
ATOM   8070  N N     . LEU C 1 181 ? 1.014    -104.516 -18.477 1.00 38.28  ? 181  LEU C N     1 
ATOM   8071  C CA    . LEU C 1 181 ? 0.049    -105.045 -17.512 1.00 33.13  ? 181  LEU C CA    1 
ATOM   8072  C C     . LEU C 1 181 ? -1.238   -105.465 -18.232 1.00 32.25  ? 181  LEU C C     1 
ATOM   8073  O O     . LEU C 1 181 ? -1.690   -106.613 -18.105 1.00 33.25  ? 181  LEU C O     1 
ATOM   8074  C CB    . LEU C 1 181 ? -0.227   -104.047 -16.392 1.00 31.09  ? 181  LEU C CB    1 
ATOM   8075  C CG    . LEU C 1 181 ? -1.269   -104.467 -15.351 1.00 31.08  ? 181  LEU C CG    1 
ATOM   8076  C CD1   . LEU C 1 181 ? -0.826   -105.688 -14.580 1.00 28.29  ? 181  LEU C CD1   1 
ATOM   8077  C CD2   . LEU C 1 181 ? -1.571   -103.350 -14.361 1.00 33.03  ? 181  LEU C CD2   1 
ATOM   8078  N N     . TYR C 1 182 ? -1.835   -104.546 -18.957 1.00 32.34  ? 182  TYR C N     1 
ATOM   8079  C CA    . TYR C 1 182 ? -3.076   -104.821 -19.667 1.00 34.90  ? 182  TYR C CA    1 
ATOM   8080  C C     . TYR C 1 182 ? -2.950   -105.838 -20.765 1.00 40.22  ? 182  TYR C C     1 
ATOM   8081  O O     . TYR C 1 182 ? -3.849   -106.586 -20.996 1.00 39.18  ? 182  TYR C O     1 
ATOM   8082  C CB    . TYR C 1 182 ? -3.803   -103.578 -20.108 1.00 31.00  ? 182  TYR C CB    1 
ATOM   8083  C CG    . TYR C 1 182 ? -4.084   -102.627 -19.008 1.00 31.92  ? 182  TYR C CG    1 
ATOM   8084  C CD1   . TYR C 1 182 ? -4.238   -103.050 -17.716 1.00 31.07  ? 182  TYR C CD1   1 
ATOM   8085  C CD2   . TYR C 1 182 ? -4.209   -101.306 -19.261 1.00 30.62  ? 182  TYR C CD2   1 
ATOM   8086  C CE1   . TYR C 1 182 ? -4.507   -102.165 -16.716 1.00 29.18  ? 182  TYR C CE1   1 
ATOM   8087  C CE2   . TYR C 1 182 ? -4.469   -100.427 -18.264 1.00 32.83  ? 182  TYR C CE2   1 
ATOM   8088  C CZ    . TYR C 1 182 ? -4.617   -100.868 -16.994 1.00 29.21  ? 182  TYR C CZ    1 
ATOM   8089  O OH    . TYR C 1 182 ? -4.865   -99.983  -16.021 1.00 27.47  ? 182  TYR C OH    1 
ATOM   8090  N N     . GLY C 1 183 ? -1.819   -105.827 -21.448 1.00 37.92  ? 183  GLY C N     1 
ATOM   8091  C CA    . GLY C 1 183 ? -1.517   -106.780 -22.476 1.00 30.24  ? 183  GLY C CA    1 
ATOM   8092  C C     . GLY C 1 183 ? -1.452   -108.167 -21.925 1.00 32.41  ? 183  GLY C C     1 
ATOM   8093  O O     . GLY C 1 183 ? -1.834   -109.076 -22.582 1.00 38.01  ? 183  GLY C O     1 
ATOM   8094  N N     . MET C 1 184 ? -0.886   -108.334 -20.747 1.00 30.56  ? 184  MET C N     1 
ATOM   8095  C CA    . MET C 1 184 ? -0.852   -109.611 -20.102 1.00 28.47  ? 184  MET C CA    1 
ATOM   8096  C C     . MET C 1 184 ? -2.266   -110.068 -19.786 1.00 33.53  ? 184  MET C C     1 
ATOM   8097  O O     . MET C 1 184 ? -2.564   -111.206 -19.924 1.00 35.47  ? 184  MET C O     1 
ATOM   8098  C CB    . MET C 1 184 ? -0.005   -109.535 -18.841 1.00 30.02  ? 184  MET C CB    1 
ATOM   8099  C CG    . MET C 1 184 ? 0.105    -110.800 -18.026 1.00 33.74  ? 184  MET C CG    1 
ATOM   8100  S SD    . MET C 1 184 ? -1.128   -111.019 -16.763 1.00 55.71  ? 184  MET C SD    1 
ATOM   8101  C CE    . MET C 1 184 ? -0.785   -109.683 -15.673 1.00 48.21  ? 184  MET C CE    1 
ATOM   8102  N N     . ILE C 1 185 ? -3.127   -109.172 -19.333 1.00 32.39  ? 185  ILE C N     1 
ATOM   8103  C CA    . ILE C 1 185 ? -4.497   -109.525 -19.044 1.00 30.88  ? 185  ILE C CA    1 
ATOM   8104  C C     . ILE C 1 185 ? -5.237   -109.961 -20.309 1.00 32.50  ? 185  ILE C C     1 
ATOM   8105  O O     . ILE C 1 185 ? -5.896   -110.943 -20.307 1.00 28.71  ? 185  ILE C O     1 
ATOM   8106  C CB    . ILE C 1 185 ? -5.259   -108.397 -18.341 1.00 29.24  ? 185  ILE C CB    1 
ATOM   8107  C CG1   . ILE C 1 185 ? -4.731   -108.189 -16.954 1.00 32.09  ? 185  ILE C CG1   1 
ATOM   8108  C CG2   . ILE C 1 185 ? -6.719   -108.724 -18.219 1.00 24.41  ? 185  ILE C CG2   1 
ATOM   8109  C CD1   . ILE C 1 185 ? -4.981   -106.821 -16.423 1.00 28.23  ? 185  ILE C CD1   1 
ATOM   8110  N N     . ARG C 1 186 ? -5.042   -109.246 -21.398 1.00 31.01  ? 186  ARG C N     1 
ATOM   8111  C CA    . ARG C 1 186 ? -5.656   -109.583 -22.655 1.00 39.50  ? 186  ARG C CA    1 
ATOM   8112  C C     . ARG C 1 186 ? -5.210   -110.947 -23.169 1.00 43.17  ? 186  ARG C C     1 
ATOM   8113  O O     . ARG C 1 186 ? -5.971   -111.647 -23.760 1.00 45.05  ? 186  ARG C O     1 
ATOM   8114  C CB    . ARG C 1 186 ? -5.424   -108.522 -23.698 1.00 34.86  ? 186  ARG C CB    1 
ATOM   8115  C CG    . ARG C 1 186 ? -5.963   -107.165 -23.341 1.00 44.63  ? 186  ARG C CG    1 
ATOM   8116  C CD    . ARG C 1 186 ? -7.315   -106.832 -23.923 1.00 45.58  ? 186  ARG C CD    1 
ATOM   8117  N NE    . ARG C 1 186 ? -8.414   -107.335 -23.138 1.00 46.37  ? 186  ARG C NE    1 
ATOM   8118  C CZ    . ARG C 1 186 ? -9.300   -106.598 -22.500 1.00 39.14  ? 186  ARG C CZ    1 
ATOM   8119  N NH1   . ARG C 1 186 ? -9.241   -105.313 -22.508 1.00 36.75  ? 186  ARG C NH1   1 
ATOM   8120  N NH2   . ARG C 1 186 ? -10.242  -107.177 -21.836 1.00 35.11  ? 186  ARG C NH2   1 
ATOM   8121  N N     . HIS C 1 187 ? -3.959   -111.300 -22.980 1.00 42.84  ? 187  HIS C N     1 
ATOM   8122  C CA    . HIS C 1 187 ? -3.496   -112.589 -23.393 1.00 36.64  ? 187  HIS C CA    1 
ATOM   8123  C C     . HIS C 1 187 ? -4.139   -113.739 -22.636 1.00 37.06  ? 187  HIS C C     1 
ATOM   8124  O O     . HIS C 1 187 ? -4.575   -114.686 -23.220 1.00 45.35  ? 187  HIS C O     1 
ATOM   8125  C CB    . HIS C 1 187 ? -1.978   -112.633 -23.285 1.00 46.14  ? 187  HIS C CB    1 
ATOM   8126  C CG    . HIS C 1 187 ? -1.397   -113.988 -23.489 1.00 54.61  ? 187  HIS C CG    1 
ATOM   8127  N ND1   . HIS C 1 187 ? -1.175   -114.517 -24.734 1.00 53.88  ? 187  HIS C ND1   1 
ATOM   8128  C CD2   . HIS C 1 187 ? -1.000   -114.925 -22.608 1.00 50.98  ? 187  HIS C CD2   1 
ATOM   8129  C CE1   . HIS C 1 187 ? -0.681   -115.727 -24.610 1.00 48.92  ? 187  HIS C CE1   1 
ATOM   8130  N NE2   . HIS C 1 187 ? -0.566   -115.998 -23.331 1.00 55.13  ? 187  HIS C NE2   1 
ATOM   8131  N N     . TYR C 1 188 ? -4.237   -113.650 -21.333 1.00 38.28  ? 188  TYR C N     1 
ATOM   8132  C CA    . TYR C 1 188 ? -4.854   -114.704 -20.557 1.00 37.33  ? 188  TYR C CA    1 
ATOM   8133  C C     . TYR C 1 188 ? -6.355   -114.595 -20.374 1.00 37.12  ? 188  TYR C C     1 
ATOM   8134  O O     . TYR C 1 188 ? -7.025   -115.562 -20.196 1.00 36.31  ? 188  TYR C O     1 
ATOM   8135  C CB    . TYR C 1 188 ? -4.189   -114.811 -19.205 1.00 44.63  ? 188  TYR C CB    1 
ATOM   8136  C CG    . TYR C 1 188 ? -2.754   -115.216 -19.265 1.00 58.59  ? 188  TYR C CG    1 
ATOM   8137  C CD1   . TYR C 1 188 ? -2.394   -116.512 -19.517 1.00 60.43  ? 188  TYR C CD1   1 
ATOM   8138  C CD2   . TYR C 1 188 ? -1.760   -114.305 -19.057 1.00 59.54  ? 188  TYR C CD2   1 
ATOM   8139  C CE1   . TYR C 1 188 ? -1.079   -116.885 -19.571 1.00 58.49  ? 188  TYR C CE1   1 
ATOM   8140  C CE2   . TYR C 1 188 ? -0.451   -114.673 -19.106 1.00 59.69  ? 188  TYR C CE2   1 
ATOM   8141  C CZ    . TYR C 1 188 ? -0.122   -115.964 -19.366 1.00 58.60  ? 188  TYR C CZ    1 
ATOM   8142  O OH    . TYR C 1 188 ? 1.180    -116.301 -19.419 1.00 53.61  ? 188  TYR C OH    1 
ATOM   8143  N N     . GLN C 1 189 ? -6.860   -113.383 -20.372 1.00 36.16  ? 189  GLN C N     1 
ATOM   8144  C CA    . GLN C 1 189 ? -8.267   -113.125 -20.188 1.00 35.45  ? 189  GLN C CA    1 
ATOM   8145  C C     . GLN C 1 189 ? -8.733   -112.134 -21.202 1.00 33.61  ? 189  GLN C C     1 
ATOM   8146  O O     . GLN C 1 189 ? -8.973   -111.020 -20.880 1.00 35.93  ? 189  GLN C O     1 
ATOM   8147  C CB    . GLN C 1 189 ? -8.492   -112.565 -18.809 1.00 29.04  ? 189  GLN C CB    1 
ATOM   8148  C CG    . GLN C 1 189 ? -8.127   -113.486 -17.695 1.00 29.46  ? 189  GLN C CG    1 
ATOM   8149  C CD    . GLN C 1 189 ? -9.220   -114.449 -17.404 1.00 36.18  ? 189  GLN C CD    1 
ATOM   8150  O OE1   . GLN C 1 189 ? -10.325  -114.205 -17.741 1.00 37.45  ? 189  GLN C OE1   1 
ATOM   8151  N NE2   . GLN C 1 189 ? -8.907   -115.537 -16.786 1.00 33.56  ? 189  GLN C NE2   1 
ATOM   8152  N N     . PRO C 1 190 ? -8.872   -112.544 -22.443 1.00 35.71  ? 190  PRO C N     1 
ATOM   8153  C CA    . PRO C 1 190 ? -9.257   -111.606 -23.483 1.00 32.09  ? 190  PRO C CA    1 
ATOM   8154  C C     . PRO C 1 190 ? -10.607  -110.963 -23.289 1.00 30.28  ? 190  PRO C C     1 
ATOM   8155  O O     . PRO C 1 190 ? -10.835  -109.897 -23.737 1.00 33.66  ? 190  PRO C O     1 
ATOM   8156  C CB    . PRO C 1 190 ? -9.251   -112.471 -24.732 1.00 26.90  ? 190  PRO C CB    1 
ATOM   8157  C CG    . PRO C 1 190 ? -9.383   -113.836 -24.250 1.00 28.39  ? 190  PRO C CG    1 
ATOM   8158  C CD    . PRO C 1 190 ? -8.640   -113.877 -22.986 1.00 34.30  ? 190  PRO C CD    1 
ATOM   8159  N N     . ASN C 1 191 ? -11.479  -111.645 -22.600 1.00 30.08  ? 191  ASN C N     1 
ATOM   8160  C CA    . ASN C 1 191 ? -12.845  -111.200 -22.408 1.00 36.63  ? 191  ASN C CA    1 
ATOM   8161  C C     . ASN C 1 191 ? -13.071  -110.401 -21.106 1.00 35.09  ? 191  ASN C C     1 
ATOM   8162  O O     . ASN C 1 191 ? -14.179  -109.952 -20.842 1.00 31.86  ? 191  ASN C O     1 
ATOM   8163  C CB    . ASN C 1 191 ? -13.800  -112.390 -22.481 1.00 36.51  ? 191  ASN C CB    1 
ATOM   8164  C CG    . ASN C 1 191 ? -15.138  -111.875 -22.950 1.00 45.41  ? 191  ASN C CG    1 
ATOM   8165  O OD1   . ASN C 1 191 ? -16.163  -112.145 -22.314 1.00 41.70  ? 191  ASN C OD1   1 
ATOM   8166  N ND2   . ASN C 1 191 ? -15.125  -111.053 -24.000 1.00 37.48  ? 191  ASN C ND2   1 
ATOM   8167  N N     . ALA C 1 192 ? -12.038  -110.214 -20.279 1.00 33.50  ? 192  ALA C N     1 
ATOM   8168  C CA    . ALA C 1 192 ? -12.189  -109.529 -19.000 1.00 38.04  ? 192  ALA C CA    1 
ATOM   8169  C C     . ALA C 1 192 ? -12.452  -108.041 -19.225 1.00 36.01  ? 192  ALA C C     1 
ATOM   8170  O O     . ALA C 1 192 ? -11.865  -107.443 -20.114 1.00 31.08  ? 192  ALA C O     1 
ATOM   8171  C CB    . ALA C 1 192 ? -10.960  -109.727 -18.149 1.00 36.05  ? 192  ALA C CB    1 
ATOM   8172  N N     . ILE C 1 193 ? -13.357  -107.449 -18.425 1.00 31.63  ? 193  ILE C N     1 
ATOM   8173  C CA    . ILE C 1 193 ? -13.528  -106.006 -18.446 1.00 27.76  ? 193  ILE C CA    1 
ATOM   8174  C C     . ILE C 1 193 ? -12.414  -105.385 -17.603 1.00 28.50  ? 193  ILE C C     1 
ATOM   8175  O O     . ILE C 1 193 ? -12.201  -105.810 -16.470 1.00 28.02  ? 193  ILE C O     1 
ATOM   8176  C CB    . ILE C 1 193 ? -14.914  -105.650 -17.892 1.00 25.02  ? 193  ILE C CB    1 
ATOM   8177  C CG1   . ILE C 1 193 ? -16.037  -106.023 -18.874 1.00 26.29  ? 193  ILE C CG1   1 
ATOM   8178  C CG2   . ILE C 1 193 ? -14.980  -104.177 -17.491 1.00 21.94  ? 193  ILE C CG2   1 
ATOM   8179  C CD1   . ILE C 1 193 ? -16.070  -105.145 -20.119 1.00 26.42  ? 193  ILE C CD1   1 
ATOM   8180  N N     . ILE C 1 194 ? -11.681  -104.413 -18.158 1.00 25.18  ? 194  ILE C N     1 
ATOM   8181  C CA    . ILE C 1 194 ? -10.702  -103.693 -17.368 1.00 26.23  ? 194  ILE C CA    1 
ATOM   8182  C C     . ILE C 1 194 ? -11.262  -102.325 -16.975 1.00 29.17  ? 194  ILE C C     1 
ATOM   8183  O O     . ILE C 1 194 ? -11.493  -101.470 -17.841 1.00 30.49  ? 194  ILE C O     1 
ATOM   8184  C CB    . ILE C 1 194 ? -9.357   -103.554 -18.106 1.00 28.21  ? 194  ILE C CB    1 
ATOM   8185  C CG1   . ILE C 1 194 ? -8.710   -104.934 -18.393 1.00 28.99  ? 194  ILE C CG1   1 
ATOM   8186  C CG2   . ILE C 1 194 ? -8.399   -102.648 -17.315 1.00 21.44  ? 194  ILE C CG2   1 
ATOM   8187  C CD1   . ILE C 1 194 ? -7.478   -104.824 -19.266 1.00 27.67  ? 194  ILE C CD1   1 
ATOM   8188  N N     . VAL C 1 195 ? -11.472  -102.119 -15.684 1.00 25.93  ? 195  VAL C N     1 
ATOM   8189  C CA    . VAL C 1 195 ? -11.979  -100.876 -15.138 1.00 25.31  ? 195  VAL C CA    1 
ATOM   8190  C C     . VAL C 1 195 ? -10.866  -100.120 -14.481 1.00 25.19  ? 195  VAL C C     1 
ATOM   8191  O O     . VAL C 1 195 ? -10.068  -100.682 -13.824 1.00 30.08  ? 195  VAL C O     1 
ATOM   8192  C CB    . VAL C 1 195 ? -13.059  -101.107 -14.076 1.00 27.74  ? 195  VAL C CB    1 
ATOM   8193  C CG1   . VAL C 1 195 ? -13.669  -99.811  -13.610 1.00 25.74  ? 195  VAL C CG1   1 
ATOM   8194  C CG2   . VAL C 1 195 ? -14.120  -102.038 -14.566 1.00 25.92  ? 195  VAL C CG2   1 
ATOM   8195  N N     . SER C 1 196 ? -10.809  -98.835  -14.682 1.00 27.51  ? 196  SER C N     1 
ATOM   8196  C CA    . SER C 1 196 ? -9.786   -98.070  -14.039 1.00 33.98  ? 196  SER C CA    1 
ATOM   8197  C C     . SER C 1 196 ? -10.354  -96.897  -13.274 1.00 34.40  ? 196  SER C C     1 
ATOM   8198  O O     . SER C 1 196 ? -11.044  -96.092  -13.818 1.00 34.08  ? 196  SER C O     1 
ATOM   8199  C CB    . SER C 1 196 ? -8.736   -97.612  -15.039 1.00 34.34  ? 196  SER C CB    1 
ATOM   8200  O OG    . SER C 1 196 ? -7.769   -96.817  -14.425 1.00 35.13  ? 196  SER C OG    1 
ATOM   8201  N N     . ASN C 1 197 ? -10.036  -96.834  -12.000 1.00 31.78  ? 197  ASN C N     1 
ATOM   8202  C CA    . ASN C 1 197 ? -10.459  -95.787  -11.116 1.00 39.92  ? 197  ASN C CA    1 
ATOM   8203  C C     . ASN C 1 197 ? -9.394   -94.766  -11.223 1.00 45.37  ? 197  ASN C C     1 
ATOM   8204  O O     . ASN C 1 197 ? -8.342   -94.958  -10.697 1.00 63.50  ? 197  ASN C O     1 
ATOM   8205  C CB    . ASN C 1 197 ? -10.452  -96.313  -9.707  1.00 46.47  ? 197  ASN C CB    1 
ATOM   8206  C CG    . ASN C 1 197 ? -11.158  -95.415  -8.744  1.00 50.70  ? 197  ASN C CG    1 
ATOM   8207  O OD1   . ASN C 1 197 ? -12.162  -94.834  -9.072  1.00 53.19  ? 197  ASN C OD1   1 
ATOM   8208  N ND2   . ASN C 1 197 ? -10.661  -95.337  -7.541  1.00 39.42  ? 197  ASN C ND2   1 
ATOM   8209  N N     . THR C 1 198 ? -9.727   -93.650  -11.827 1.00 52.40  ? 198  THR C N     1 
ATOM   8210  C CA    . THR C 1 198 ? -8.823   -92.570  -12.147 1.00 81.20  ? 198  THR C CA    1 
ATOM   8211  C C     . THR C 1 198 ? -7.703   -93.104  -13.029 1.00 78.80  ? 198  THR C C     1 
ATOM   8212  O O     . THR C 1 198 ? -7.946   -93.476  -14.175 1.00 73.14  ? 198  THR C O     1 
ATOM   8213  C CB    . THR C 1 198 ? -8.238   -91.781  -10.965 1.00 87.52  ? 198  THR C CB    1 
ATOM   8214  O OG1   . THR C 1 198 ? -9.151   -90.770  -10.545 1.00 76.54  ? 198  THR C OG1   1 
ATOM   8215  C CG2   . THR C 1 198 ? -6.972   -91.154  -11.408 1.00 90.57  ? 198  THR C CG2   1 
ATOM   8216  N N     . GLN C 1 205 ? -8.980   -87.877  -22.448 1.00 87.47  ? 205  GLN C N     1 
ATOM   8217  C CA    . GLN C 1 205 ? -8.147   -88.957  -23.052 1.00 99.25  ? 205  GLN C CA    1 
ATOM   8218  C C     . GLN C 1 205 ? -7.842   -90.039  -22.009 1.00 85.10  ? 205  GLN C C     1 
ATOM   8219  O O     . GLN C 1 205 ? -7.419   -89.732  -20.900 1.00 74.89  ? 205  GLN C O     1 
ATOM   8220  C CB    . GLN C 1 205 ? -6.871   -88.369  -23.638 1.00 100.51 ? 205  GLN C CB    1 
ATOM   8221  C CG    . GLN C 1 205 ? -6.117   -89.314  -24.569 1.00 109.75 ? 205  GLN C CG    1 
ATOM   8222  C CD    . GLN C 1 205 ? -5.075   -88.606  -25.407 1.00 134.30 ? 205  GLN C CD    1 
ATOM   8223  O OE1   . GLN C 1 205 ? -5.013   -87.371  -25.484 1.00 140.63 ? 205  GLN C OE1   1 
ATOM   8224  N NE2   . GLN C 1 205 ? -4.233   -89.387  -26.072 1.00 131.80 ? 205  GLN C NE2   1 
ATOM   8225  N N     . VAL C 1 206 ? -8.067   -91.305  -22.392 1.00 85.15  ? 206  VAL C N     1 
ATOM   8226  C CA    . VAL C 1 206 ? -7.984   -92.466  -21.506 1.00 72.53  ? 206  VAL C CA    1 
ATOM   8227  C C     . VAL C 1 206 ? -6.534   -92.920  -21.363 1.00 59.18  ? 206  VAL C C     1 
ATOM   8228  O O     . VAL C 1 206 ? -5.718   -92.715  -22.246 1.00 62.12  ? 206  VAL C O     1 
ATOM   8229  C CB    . VAL C 1 206 ? -8.889   -93.609  -21.999 1.00 75.01  ? 206  VAL C CB    1 
ATOM   8230  C CG1   . VAL C 1 206 ? -8.957   -94.721  -20.962 1.00 73.83  ? 206  VAL C CG1   1 
ATOM   8231  C CG2   . VAL C 1 206 ? -10.298  -93.111  -22.326 1.00 76.35  ? 206  VAL C CG2   1 
ATOM   8232  N N     . SER C 1 207 ? -6.201   -93.556  -20.244 1.00 58.67  ? 207  SER C N     1 
ATOM   8233  C CA    . SER C 1 207 ? -4.798   -93.740  -19.892 1.00 58.71  ? 207  SER C CA    1 
ATOM   8234  C C     . SER C 1 207 ? -4.140   -94.912  -20.639 1.00 56.42  ? 207  SER C C     1 
ATOM   8235  O O     . SER C 1 207 ? -2.918   -95.043  -20.600 1.00 56.21  ? 207  SER C O     1 
ATOM   8236  C CB    . SER C 1 207 ? -4.622   -93.837  -18.387 1.00 46.74  ? 207  SER C CB    1 
ATOM   8237  O OG    . SER C 1 207 ? -5.094   -95.093  -17.920 1.00 51.00  ? 207  SER C OG    1 
ATOM   8238  N N     . ASP C 1 208 ? -4.936   -95.768  -21.299 1.00 44.26  ? 208  ASP C N     1 
ATOM   8239  C CA    . ASP C 1 208 ? -4.405   -96.877  -22.062 1.00 41.18  ? 208  ASP C CA    1 
ATOM   8240  C C     . ASP C 1 208 ? -5.504   -97.447  -22.952 1.00 44.39  ? 208  ASP C C     1 
ATOM   8241  O O     . ASP C 1 208 ? -6.634   -97.619  -22.505 1.00 40.30  ? 208  ASP C O     1 
ATOM   8242  C CB    . ASP C 1 208 ? -3.884   -98.009  -21.196 1.00 38.13  ? 208  ASP C CB    1 
ATOM   8243  C CG    . ASP C 1 208 ? -3.093   -99.065  -21.970 1.00 40.32  ? 208  ASP C CG    1 
ATOM   8244  O OD1   . ASP C 1 208 ? -1.864   -98.883  -22.148 1.00 40.96  ? 208  ASP C OD1   1 
ATOM   8245  O OD2   . ASP C 1 208 ? -3.713   -100.018 -22.462 1.00 42.17  ? 208  ASP C OD2   1 
ATOM   8246  N N     . PRO C 1 209 ? -5.200   -97.798  -24.227 1.00 49.09  ? 209  PRO C N     1 
ATOM   8247  C CA    . PRO C 1 209 ? -6.217   -98.331  -25.136 1.00 43.91  ? 209  PRO C CA    1 
ATOM   8248  C C     . PRO C 1 209 ? -6.964   -99.551  -24.598 1.00 40.82  ? 209  PRO C C     1 
ATOM   8249  O O     . PRO C 1 209 ? -8.096   -99.803  -25.004 1.00 41.95  ? 209  PRO C O     1 
ATOM   8250  C CB    . PRO C 1 209 ? -5.454   -98.611  -26.443 1.00 41.87  ? 209  PRO C CB    1 
ATOM   8251  C CG    . PRO C 1 209 ? -4.276   -97.647  -26.343 1.00 43.43  ? 209  PRO C CG    1 
ATOM   8252  C CD    . PRO C 1 209 ? -3.882   -97.649  -24.874 1.00 45.64  ? 209  PRO C CD    1 
ATOM   8253  N N     . GLU C 1 210 ? -6.343   -100.309 -23.686 1.00 32.62  ? 210  GLU C N     1 
ATOM   8254  C CA    . GLU C 1 210 ? -6.949   -101.560 -23.236 1.00 34.84  ? 210  GLU C CA    1 
ATOM   8255  C C     . GLU C 1 210 ? -8.021   -101.354 -22.153 1.00 36.84  ? 210  GLU C C     1 
ATOM   8256  O O     . GLU C 1 210 ? -8.768   -102.289 -21.848 1.00 35.27  ? 210  GLU C O     1 
ATOM   8257  C CB    . GLU C 1 210 ? -5.904   -102.578 -22.787 1.00 32.72  ? 210  GLU C CB    1 
ATOM   8258  C CG    . GLU C 1 210 ? -5.153   -103.196 -23.965 1.00 39.49  ? 210  GLU C CG    1 
ATOM   8259  C CD    . GLU C 1 210 ? -6.048   -103.917 -24.968 1.00 50.74  ? 210  GLU C CD    1 
ATOM   8260  O OE1   . GLU C 1 210 ? -7.231   -104.328 -24.667 1.00 52.65  ? 210  GLU C OE1   1 
ATOM   8261  O OE2   . GLU C 1 210 ? -5.516   -104.064 -26.083 1.00 47.86  ? 210  GLU C OE2   1 
ATOM   8262  N N     . ILE C 1 211 ? -8.092   -100.150 -21.558 1.00 33.31  ? 211  ILE C N     1 
ATOM   8263  C CA    . ILE C 1 211 ? -9.133   -99.837  -20.588 1.00 35.96  ? 211  ILE C CA    1 
ATOM   8264  C C     . ILE C 1 211 ? -10.515  -99.905  -21.249 1.00 31.51  ? 211  ILE C C     1 
ATOM   8265  O O     . ILE C 1 211 ? -10.703  -99.371  -22.332 1.00 34.80  ? 211  ILE C O     1 
ATOM   8266  C CB    . ILE C 1 211 ? -8.862   -98.467  -19.933 1.00 32.26  ? 211  ILE C CB    1 
ATOM   8267  C CG1   . ILE C 1 211 ? -7.795   -98.594  -18.866 1.00 32.34  ? 211  ILE C CG1   1 
ATOM   8268  C CG2   . ILE C 1 211 ? -10.148  -97.903  -19.339 1.00 32.01  ? 211  ILE C CG2   1 
ATOM   8269  C CD1   . ILE C 1 211 ? -7.065   -97.289  -18.596 1.00 34.88  ? 211  ILE C CD1   1 
ATOM   8270  N N     . ASP C 1 212 ? -11.482  -100.541 -20.572 1.00 30.59  ? 212  ASP C N     1 
ATOM   8271  C CA    . ASP C 1 212 ? -12.839  -100.711 -21.069 1.00 27.28  ? 212  ASP C CA    1 
ATOM   8272  C C     . ASP C 1 212 ? -13.838  -99.784  -20.364 1.00 32.90  ? 212  ASP C C     1 
ATOM   8273  O O     . ASP C 1 212 ? -14.871  -99.427  -20.935 1.00 33.85  ? 212  ASP C O     1 
ATOM   8274  C CB    . ASP C 1 212 ? -13.270  -102.153 -20.877 1.00 32.46  ? 212  ASP C CB    1 
ATOM   8275  C CG    . ASP C 1 212 ? -12.437  -103.190 -21.627 1.00 31.81  ? 212  ASP C CG    1 
ATOM   8276  O OD1   . ASP C 1 212 ? -12.028  -102.894 -22.769 1.00 36.72  ? 212  ASP C OD1   1 
ATOM   8277  O OD2   . ASP C 1 212 ? -12.224  -104.309 -21.083 1.00 34.02  ? 212  ASP C OD2   1 
ATOM   8278  N N     . VAL C 1 213 ? -13.632  -99.513  -19.082 1.00 28.91  ? 213  VAL C N     1 
ATOM   8279  C CA    . VAL C 1 213 ? -14.504  -98.708  -18.248 1.00 23.62  ? 213  VAL C CA    1 
ATOM   8280  C C     . VAL C 1 213 ? -13.721  -97.717  -17.402 1.00 24.96  ? 213  VAL C C     1 
ATOM   8281  O O     . VAL C 1 213 ? -12.726  -98.029  -16.890 1.00 32.28  ? 213  VAL C O     1 
ATOM   8282  C CB    . VAL C 1 213 ? -15.357  -99.597  -17.304 1.00 26.66  ? 213  VAL C CB    1 
ATOM   8283  C CG1   . VAL C 1 213 ? -16.356  -98.797  -16.500 1.00 22.69  ? 213  VAL C CG1   1 
ATOM   8284  C CG2   . VAL C 1 213 ? -16.081  -100.681 -18.055 1.00 22.83  ? 213  VAL C CG2   1 
ATOM   8285  N N     . VAL C 1 214 ? -14.215  -96.515  -17.281 1.00 25.42  ? 214  VAL C N     1 
ATOM   8286  C CA    . VAL C 1 214 ? -13.651  -95.472  -16.487 1.00 31.39  ? 214  VAL C CA    1 
ATOM   8287  C C     . VAL C 1 214 ? -14.659  -95.091  -15.405 1.00 28.65  ? 214  VAL C C     1 
ATOM   8288  O O     . VAL C 1 214 ? -15.817  -95.157  -15.632 1.00 29.28  ? 214  VAL C O     1 
ATOM   8289  C CB    . VAL C 1 214 ? -13.289  -94.308  -17.409 1.00 34.55  ? 214  VAL C CB    1 
ATOM   8290  C CG1   . VAL C 1 214 ? -13.227  -92.998  -16.702 1.00 39.70  ? 214  VAL C CG1   1 
ATOM   8291  C CG2   . VAL C 1 214 ? -11.978  -94.592  -18.071 1.00 41.11  ? 214  VAL C CG2   1 
ATOM   8292  N N     . THR C 1 215 ? -14.196  -94.814  -14.201 1.00 28.92  ? 215  THR C N     1 
ATOM   8293  C CA    . THR C 1 215 ? -15.042  -94.386  -13.089 1.00 33.02  ? 215  THR C CA    1 
ATOM   8294  C C     . THR C 1 215 ? -15.339  -92.896  -13.040 1.00 34.32  ? 215  THR C C     1 
ATOM   8295  O O     . THR C 1 215 ? -14.552  -92.106  -13.422 1.00 41.65  ? 215  THR C O     1 
ATOM   8296  C CB    . THR C 1 215 ? -14.458  -94.769  -11.757 1.00 28.17  ? 215  THR C CB    1 
ATOM   8297  O OG1   . THR C 1 215 ? -13.245  -94.077  -11.591 1.00 29.72  ? 215  THR C OG1   1 
ATOM   8298  C CG2   . THR C 1 215 ? -14.211  -96.207  -11.714 1.00 27.49  ? 215  THR C CG2   1 
ATOM   8299  N N     . TYR C 1 216 ? -16.490  -92.523  -12.537 1.00 31.58  ? 216  TYR C N     1 
ATOM   8300  C CA    . TYR C 1 216 ? -16.883  -91.147  -12.457 1.00 32.09  ? 216  TYR C CA    1 
ATOM   8301  C C     . TYR C 1 216 ? -17.440  -90.809  -11.101 1.00 36.41  ? 216  TYR C C     1 
ATOM   8302  O O     . TYR C 1 216 ? -17.820  -91.671  -10.356 1.00 36.09  ? 216  TYR C O     1 
ATOM   8303  C CB    . TYR C 1 216 ? -17.955  -90.852  -13.490 1.00 35.68  ? 216  TYR C CB    1 
ATOM   8304  C CG    . TYR C 1 216 ? -17.493  -90.907  -14.904 1.00 44.69  ? 216  TYR C CG    1 
ATOM   8305  C CD1   . TYR C 1 216 ? -17.437  -92.082  -15.577 1.00 39.70  ? 216  TYR C CD1   1 
ATOM   8306  C CD2   . TYR C 1 216 ? -17.119  -89.775  -15.565 1.00 47.94  ? 216  TYR C CD2   1 
ATOM   8307  C CE1   . TYR C 1 216 ? -17.003  -92.135  -16.849 1.00 43.70  ? 216  TYR C CE1   1 
ATOM   8308  C CE2   . TYR C 1 216 ? -16.691  -89.816  -16.857 1.00 46.44  ? 216  TYR C CE2   1 
ATOM   8309  C CZ    . TYR C 1 216 ? -16.636  -91.002  -17.486 1.00 45.91  ? 216  TYR C CZ    1 
ATOM   8310  O OH    . TYR C 1 216 ? -16.222  -91.051  -18.760 1.00 51.25  ? 216  TYR C OH    1 
ATOM   8311  N N     . GLU C 1 217 ? -17.443  -89.535  -10.775 1.00 38.16  ? 217  GLU C N     1 
ATOM   8312  C CA    . GLU C 1 217 ? -18.025  -89.068  -9.539  1.00 46.55  ? 217  GLU C CA    1 
ATOM   8313  C C     . GLU C 1 217 ? -19.488  -89.333  -9.623  1.00 41.90  ? 217  GLU C C     1 
ATOM   8314  O O     . GLU C 1 217 ? -20.089  -89.107  -10.623 1.00 48.74  ? 217  GLU C O     1 
ATOM   8315  C CB    . GLU C 1 217 ? -17.812  -87.573  -9.374  1.00 51.32  ? 217  GLU C CB    1 
ATOM   8316  C CG    . GLU C 1 217 ? -16.583  -87.221  -8.589  1.00 74.77  ? 217  GLU C CG    1 
ATOM   8317  C CD    . GLU C 1 217 ? -16.217  -85.756  -8.656  1.00 95.93  ? 217  GLU C CD    1 
ATOM   8318  O OE1   . GLU C 1 217 ? -15.013  -85.450  -8.711  1.00 99.73  ? 217  GLU C OE1   1 
ATOM   8319  O OE2   . GLU C 1 217 ? -17.115  -84.902  -8.643  1.00 98.37  ? 217  GLU C OE2   1 
ATOM   8320  N N     . ARG C 1 218 ? -20.105  -89.720  -8.533  1.00 43.70  ? 218  ARG C N     1 
ATOM   8321  C CA    . ARG C 1 218 ? -21.514  -90.039  -8.537  1.00 44.45  ? 218  ARG C CA    1 
ATOM   8322  C C     . ARG C 1 218 ? -22.466  -88.908  -8.840  1.00 44.81  ? 218  ARG C C     1 
ATOM   8323  O O     . ARG C 1 218 ? -23.536  -89.136  -9.334  1.00 40.88  ? 218  ARG C O     1 
ATOM   8324  C CB    . ARG C 1 218 ? -21.923  -90.854  -7.329  1.00 43.02  ? 218  ARG C CB    1 
ATOM   8325  C CG    . ARG C 1 218 ? -22.335  -90.080  -6.124  1.00 44.78  ? 218  ARG C CG    1 
ATOM   8326  C CD    . ARG C 1 218 ? -22.479  -91.007  -4.949  1.00 45.42  ? 218  ARG C CD    1 
ATOM   8327  N NE    . ARG C 1 218 ? -23.042  -90.294  -3.839  1.00 47.75  ? 218  ARG C NE    1 
ATOM   8328  C CZ    . ARG C 1 218 ? -22.318  -89.710  -2.923  1.00 46.50  ? 218  ARG C CZ    1 
ATOM   8329  N NH1   . ARG C 1 218 ? -21.012  -89.772  -2.981  1.00 46.10  ? 218  ARG C NH1   1 
ATOM   8330  N NH2   . ARG C 1 218 ? -22.896  -89.052  -1.966  1.00 48.38  ? 218  ARG C NH2   1 
ATOM   8331  N N     . ARG C 1 219 ? -22.048  -87.693  -8.570  1.00 43.20  ? 219  ARG C N     1 
ATOM   8332  C CA    . ARG C 1 219 ? -22.837  -86.534  -8.830  1.00 46.46  ? 219  ARG C CA    1 
ATOM   8333  C C     . ARG C 1 219 ? -22.696  -85.953  -10.191 1.00 41.71  ? 219  ARG C C     1 
ATOM   8334  O O     . ARG C 1 219 ? -23.212  -84.900  -10.380 1.00 41.13  ? 219  ARG C O     1 
ATOM   8335  C CB    . ARG C 1 219 ? -22.505  -85.445  -7.848  1.00 53.01  ? 219  ARG C CB    1 
ATOM   8336  C CG    . ARG C 1 219 ? -23.270  -85.575  -6.576  1.00 62.95  ? 219  ARG C CG    1 
ATOM   8337  C CD    . ARG C 1 219 ? -22.424  -85.009  -5.483  1.00 81.73  ? 219  ARG C CD    1 
ATOM   8338  N NE    . ARG C 1 219 ? -22.990  -85.263  -4.184  1.00 90.59  ? 219  ARG C NE    1 
ATOM   8339  C CZ    . ARG C 1 219 ? -22.307  -85.773  -3.178  1.00 99.86  ? 219  ARG C CZ    1 
ATOM   8340  N NH1   . ARG C 1 219 ? -21.024  -86.078  -3.323  1.00 73.76  ? 219  ARG C NH1   1 
ATOM   8341  N NH2   . ARG C 1 219 ? -22.920  -85.955  -2.023  1.00 101.26 ? 219  ARG C NH2   1 
ATOM   8342  N N     . THR C 1 220 ? -22.007  -86.613  -11.110 1.00 36.59  ? 220  THR C N     1 
ATOM   8343  C CA    . THR C 1 220 ? -21.812  -86.100  -12.446 1.00 42.82  ? 220  THR C CA    1 
ATOM   8344  C C     . THR C 1 220 ? -23.165  -85.763  -13.046 1.00 44.71  ? 220  THR C C     1 
ATOM   8345  O O     . THR C 1 220 ? -24.016  -86.609  -13.138 1.00 38.08  ? 220  THR C O     1 
ATOM   8346  C CB    . THR C 1 220 ? -21.187  -87.197  -13.306 1.00 41.88  ? 220  THR C CB    1 
ATOM   8347  O OG1   . THR C 1 220 ? -19.994  -87.656  -12.704 1.00 39.06  ? 220  THR C OG1   1 
ATOM   8348  C CG2   . THR C 1 220 ? -20.901  -86.712  -14.651 1.00 39.58  ? 220  THR C CG2   1 
ATOM   8349  N N     . PRO C 1 221 ? -23.316  -84.520  -13.519 1.00 50.66  ? 221  PRO C N     1 
ATOM   8350  C CA    . PRO C 1 221 ? -24.669  -84.102  -13.924 1.00 52.10  ? 221  PRO C CA    1 
ATOM   8351  C C     . PRO C 1 221 ? -25.136  -84.656  -15.278 1.00 48.42  ? 221  PRO C C     1 
ATOM   8352  O O     . PRO C 1 221 ? -26.319  -84.953  -15.434 1.00 48.52  ? 221  PRO C O     1 
ATOM   8353  C CB    . PRO C 1 221 ? -24.641  -82.562  -13.827 1.00 44.33  ? 221  PRO C CB    1 
ATOM   8354  C CG    . PRO C 1 221 ? -23.144  -82.211  -13.966 1.00 42.10  ? 221  PRO C CG    1 
ATOM   8355  C CD    . PRO C 1 221 ? -22.309  -83.446  -13.648 1.00 44.86  ? 221  PRO C CD    1 
ATOM   8356  N N     . ASP C 1 222 ? -24.203  -84.820  -16.235 1.00 48.98  ? 222  ASP C N     1 
ATOM   8357  C CA    . ASP C 1 222 ? -24.573  -85.095  -17.617 1.00 55.32  ? 222  ASP C CA    1 
ATOM   8358  C C     . ASP C 1 222 ? -24.059  -86.461  -18.052 1.00 47.08  ? 222  ASP C C     1 
ATOM   8359  O O     . ASP C 1 222 ? -23.124  -86.989  -17.441 1.00 42.10  ? 222  ASP C O     1 
ATOM   8360  C CB    . ASP C 1 222 ? -23.980  -84.091  -18.596 1.00 72.76  ? 222  ASP C CB    1 
ATOM   8361  C CG    . ASP C 1 222 ? -24.195  -82.622  -18.266 1.00 88.83  ? 222  ASP C CG    1 
ATOM   8362  O OD1   . ASP C 1 222 ? -25.388  -82.199  -18.223 1.00 74.79  ? 222  ASP C OD1   1 
ATOM   8363  O OD2   . ASP C 1 222 ? -23.163  -81.933  -18.049 1.00 81.53  ? 222  ASP C OD2   1 
ATOM   8364  N N     . GLU C 1 223 ? -24.654  -86.972  -19.141 1.00 44.54  ? 223  GLU C N     1 
ATOM   8365  C CA    . GLU C 1 223 ? -24.225  -88.194  -19.810 1.00 52.58  ? 223  GLU C CA    1 
ATOM   8366  C C     . GLU C 1 223 ? -22.695  -88.237  -19.942 1.00 54.78  ? 223  GLU C C     1 
ATOM   8367  O O     . GLU C 1 223 ? -22.061  -87.244  -20.294 1.00 53.69  ? 223  GLU C O     1 
ATOM   8368  C CB    . GLU C 1 223 ? -24.962  -88.317  -21.146 1.00 55.00  ? 223  GLU C CB    1 
ATOM   8369  C CG    . GLU C 1 223 ? -24.611  -89.620  -21.862 1.00 70.69  ? 223  GLU C CG    1 
ATOM   8370  C CD    . GLU C 1 223 ? -25.374  -89.926  -23.129 1.00 69.96  ? 223  GLU C CD    1 
ATOM   8371  O OE1   . GLU C 1 223 ? -26.254  -89.132  -23.508 1.00 63.24  ? 223  GLU C OE1   1 
ATOM   8372  O OE2   . GLU C 1 223 ? -25.122  -91.011  -23.687 1.00 77.39  ? 223  GLU C OE2   1 
ATOM   8373  N N     . ILE C 1 224 ? -22.093  -89.396  -19.628 1.00 50.57  ? 224  ILE C N     1 
ATOM   8374  C CA    . ILE C 1 224 ? -20.646  -89.502  -19.476 1.00 50.59  ? 224  ILE C CA    1 
ATOM   8375  C C     . ILE C 1 224 ? -19.978  -89.540  -20.858 1.00 56.29  ? 224  ILE C C     1 
ATOM   8376  O O     . ILE C 1 224 ? -20.642  -89.706  -21.889 1.00 44.01  ? 224  ILE C O     1 
ATOM   8377  C CB    . ILE C 1 224 ? -20.289  -90.748  -18.649 1.00 46.52  ? 224  ILE C CB    1 
ATOM   8378  C CG1   . ILE C 1 224 ? -20.829  -91.974  -19.325 1.00 46.35  ? 224  ILE C CG1   1 
ATOM   8379  C CG2   . ILE C 1 224 ? -20.785  -90.675  -17.199 1.00 42.60  ? 224  ILE C CG2   1 
ATOM   8380  C CD1   . ILE C 1 224 ? -19.945  -93.184  -19.162 1.00 53.48  ? 224  ILE C CD1   1 
ATOM   8381  N N     . TYR C 1 225 ? -18.643  -89.414  -20.857 1.00 63.48  ? 225  TYR C N     1 
ATOM   8382  C CA    . TYR C 1 225 ? -17.806  -89.399  -22.052 1.00 73.95  ? 225  TYR C CA    1 
ATOM   8383  C C     . TYR C 1 225 ? -17.444  -90.823  -22.499 1.00 68.68  ? 225  TYR C C     1 
ATOM   8384  O O     . TYR C 1 225 ? -16.968  -91.635  -21.704 1.00 68.74  ? 225  TYR C O     1 
ATOM   8385  C CB    . TYR C 1 225 ? -16.545  -88.633  -21.621 1.00 101.78 ? 225  TYR C CB    1 
ATOM   8386  C CG    . TYR C 1 225 ? -15.421  -88.609  -22.656 1.00 127.23 ? 225  TYR C CG    1 
ATOM   8387  C CD1   . TYR C 1 225 ? -15.596  -88.003  -23.910 1.00 126.91 ? 225  TYR C CD1   1 
ATOM   8388  C CD2   . TYR C 1 225 ? -14.190  -89.216  -22.382 1.00 112.01 ? 225  TYR C CD2   1 
ATOM   8389  C CE1   . TYR C 1 225 ? -14.581  -88.010  -24.858 1.00 123.61 ? 225  TYR C CE1   1 
ATOM   8390  C CE2   . TYR C 1 225 ? -13.163  -89.217  -23.319 1.00 114.07 ? 225  TYR C CE2   1 
ATOM   8391  C CZ    . TYR C 1 225 ? -13.362  -88.609  -24.555 1.00 133.21 ? 225  TYR C CZ    1 
ATOM   8392  O OH    . TYR C 1 225 ? -12.348  -88.622  -25.469 1.00 140.29 ? 225  TYR C OH    1 
ATOM   8393  N N     . HIS C 1 226 ? -17.602  -91.120  -23.796 1.00 60.81  ? 226  HIS C N     1 
ATOM   8394  C CA    . HIS C 1 226 ? -17.374  -92.481  -24.265 1.00 53.79  ? 226  HIS C CA    1 
ATOM   8395  C C     . HIS C 1 226 ? -16.099  -92.678  -25.097 1.00 53.69  ? 226  HIS C C     1 
ATOM   8396  O O     . HIS C 1 226 ? -15.888  -93.765  -25.614 1.00 48.36  ? 226  HIS C O     1 
ATOM   8397  C CB    . HIS C 1 226 ? -18.628  -92.997  -24.972 1.00 44.35  ? 226  HIS C CB    1 
ATOM   8398  C CG    . HIS C 1 226 ? -19.761  -93.176  -24.033 1.00 46.63  ? 226  HIS C CG    1 
ATOM   8399  N ND1   . HIS C 1 226 ? -19.664  -93.988  -22.921 1.00 47.35  ? 226  HIS C ND1   1 
ATOM   8400  C CD2   . HIS C 1 226 ? -21.005  -92.691  -24.041 1.00 47.80  ? 226  HIS C CD2   1 
ATOM   8401  C CE1   . HIS C 1 226 ? -20.821  -93.970  -22.271 1.00 47.52  ? 226  HIS C CE1   1 
ATOM   8402  N NE2   . HIS C 1 226 ? -21.643  -93.191  -22.933 1.00 50.17  ? 226  HIS C NE2   1 
ATOM   8403  N N     . GLY C 1 227 ? -15.236  -91.664  -25.205 1.00 61.31  ? 227  GLY C N     1 
ATOM   8404  C CA    . GLY C 1 227 ? -14.044  -91.696  -26.058 1.00 76.53  ? 227  GLY C CA    1 
ATOM   8405  C C     . GLY C 1 227 ? -14.167  -90.787  -27.294 1.00 87.42  ? 227  GLY C C     1 
ATOM   8406  O O     . GLY C 1 227 ? -15.279  -90.424  -27.689 1.00 71.58  ? 227  GLY C O     1 
ATOM   8407  N N     . ALA C 1 228 ? -13.016  -90.436  -27.904 1.00 99.11  ? 228  ALA C N     1 
ATOM   8408  C CA    . ALA C 1 228 ? -12.970  -89.625  -29.117 1.00 102.77 ? 228  ALA C CA    1 
ATOM   8409  C C     . ALA C 1 228 ? -13.637  -90.378  -30.271 1.00 102.16 ? 228  ALA C C     1 
ATOM   8410  O O     . ALA C 1 228 ? -13.605  -91.603  -30.284 1.00 99.35  ? 228  ALA C O     1 
ATOM   8411  C CB    . ALA C 1 228 ? -11.544  -89.237  -29.439 1.00 93.93  ? 228  ALA C CB    1 
ATOM   8412  N N     . PRO C 1 229 ? -14.258  -89.707  -31.280 1.00 109.91 ? 229  PRO C N     1 
ATOM   8413  C CA    . PRO C 1 229 ? -14.805  -90.434  -32.430 1.00 107.98 ? 229  PRO C CA    1 
ATOM   8414  C C     . PRO C 1 229 ? -13.713  -91.114  -33.269 1.00 98.63  ? 229  PRO C C     1 
ATOM   8415  O O     . PRO C 1 229 ? -12.588  -90.624  -33.369 1.00 79.21  ? 229  PRO C O     1 
ATOM   8416  C CB    . PRO C 1 229 ? -15.758  -89.453  -33.122 1.00 95.82  ? 229  PRO C CB    1 
ATOM   8417  C CG    . PRO C 1 229 ? -15.355  -88.092  -32.562 1.00 107.43 ? 229  PRO C CG    1 
ATOM   8418  C CD    . PRO C 1 229 ? -14.413  -88.246  -31.385 1.00 106.78 ? 229  PRO C CD    1 
ATOM   8419  N N     . ASN C 1 230 ? -14.022  -92.298  -33.808 1.00 91.55  ? 230  ASN C N     1 
ATOM   8420  C CA    . ASN C 1 230 ? -13.039  -93.154  -34.457 1.00 94.74  ? 230  ASN C CA    1 
ATOM   8421  C C     . ASN C 1 230 ? -12.177  -93.924  -33.456 1.00 85.42  ? 230  ASN C C     1 
ATOM   8422  O O     . ASN C 1 230 ? -11.387  -94.756  -33.894 1.00 83.95  ? 230  ASN C O     1 
ATOM   8423  C CB    . ASN C 1 230 ? -12.219  -92.453  -35.541 1.00 100.79 ? 230  ASN C CB    1 
ATOM   8424  C CG    . ASN C 1 230 ? -12.962  -92.410  -36.855 1.00 107.11 ? 230  ASN C CG    1 
ATOM   8425  O OD1   . ASN C 1 230 ? -13.169  -91.322  -37.404 1.00 102.05 ? 230  ASN C OD1   1 
ATOM   8426  N ND2   . ASN C 1 230 ? -13.414  -93.561  -37.329 1.00 96.06  ? 230  ASN C ND2   1 
ATOM   8427  N N     . GLU C 1 231 ? -12.338  -93.689  -32.141 1.00 82.80  ? 231  GLU C N     1 
ATOM   8428  C CA    . GLU C 1 231 ? -11.593  -94.449  -31.150 1.00 71.75  ? 231  GLU C CA    1 
ATOM   8429  C C     . GLU C 1 231 ? -12.481  -95.480  -30.445 1.00 66.92  ? 231  GLU C C     1 
ATOM   8430  O O     . GLU C 1 231 ? -13.679  -95.565  -30.709 1.00 56.24  ? 231  GLU C O     1 
ATOM   8431  C CB    . GLU C 1 231 ? -10.826  -93.498  -30.240 1.00 75.92  ? 231  GLU C CB    1 
ATOM   8432  C CG    . GLU C 1 231 ? -9.860   -92.640  -31.047 1.00 89.53  ? 231  GLU C CG    1 
ATOM   8433  C CD    . GLU C 1 231 ? -8.759   -92.034  -30.196 1.00 99.98  ? 231  GLU C CD    1 
ATOM   8434  O OE1   . GLU C 1 231 ? -7.833   -91.439  -30.782 1.00 96.30  ? 231  GLU C OE1   1 
ATOM   8435  O OE2   . GLU C 1 231 ? -8.818   -92.151  -28.954 1.00 89.68  ? 231  GLU C OE2   1 
ATOM   8436  N N     . LYS C 1 232 ? -11.864  -96.323  -29.607 1.00 59.11  ? 232  LYS C N     1 
ATOM   8437  C CA    . LYS C 1 232 ? -12.589  -97.344  -28.869 1.00 43.72  ? 232  LYS C CA    1 
ATOM   8438  C C     . LYS C 1 232 ? -13.612  -96.670  -27.946 1.00 46.52  ? 232  LYS C C     1 
ATOM   8439  O O     . LYS C 1 232 ? -13.303  -95.686  -27.266 1.00 39.60  ? 232  LYS C O     1 
ATOM   8440  C CB    . LYS C 1 232 ? -11.551  -98.097  -28.039 1.00 37.14  ? 232  LYS C CB    1 
ATOM   8441  C CG    . LYS C 1 232 ? -12.104  -99.342  -27.361 1.00 36.53  ? 232  LYS C CG    1 
ATOM   8442  C CD    . LYS C 1 232 ? -11.232  -99.672  -26.152 1.00 34.34  ? 232  LYS C CD    1 
ATOM   8443  C CE    . LYS C 1 232 ? -11.687  -100.881 -25.428 1.00 31.13  ? 232  LYS C CE    1 
ATOM   8444  N NZ    . LYS C 1 232 ? -10.718  -101.286 -24.417 1.00 32.31  ? 232  LYS C NZ    1 
ATOM   8445  N N     . TYR C 1 233 ? -14.843  -97.186  -27.954 1.00 43.88  ? 233  TYR C N     1 
ATOM   8446  C CA    . TYR C 1 233 ? -15.849  -96.776  -26.982 1.00 42.09  ? 233  TYR C CA    1 
ATOM   8447  C C     . TYR C 1 233 ? -15.502  -97.297  -25.580 1.00 38.19  ? 233  TYR C C     1 
ATOM   8448  O O     . TYR C 1 233 ? -15.281  -98.486  -25.388 1.00 35.00  ? 233  TYR C O     1 
ATOM   8449  C CB    . TYR C 1 233 ? -17.149  -97.421  -27.435 1.00 32.76  ? 233  TYR C CB    1 
ATOM   8450  C CG    . TYR C 1 233 ? -18.335  -97.129  -26.529 1.00 40.29  ? 233  TYR C CG    1 
ATOM   8451  C CD1   . TYR C 1 233 ? -18.560  -97.868  -25.357 1.00 38.60  ? 233  TYR C CD1   1 
ATOM   8452  C CD2   . TYR C 1 233 ? -19.264  -96.140  -26.861 1.00 37.81  ? 233  TYR C CD2   1 
ATOM   8453  C CE1   . TYR C 1 233 ? -19.663  -97.629  -24.553 1.00 34.24  ? 233  TYR C CE1   1 
ATOM   8454  C CE2   . TYR C 1 233 ? -20.381  -95.899  -26.069 1.00 35.29  ? 233  TYR C CE2   1 
ATOM   8455  C CZ    . TYR C 1 233 ? -20.574  -96.641  -24.912 1.00 38.64  ? 233  TYR C CZ    1 
ATOM   8456  O OH    . TYR C 1 233 ? -21.664  -96.407  -24.121 1.00 33.02  ? 233  TYR C OH    1 
ATOM   8457  N N     . VAL C 1 234 ? -15.504  -96.404  -24.591 1.00 33.95  ? 234  VAL C N     1 
ATOM   8458  C CA    . VAL C 1 234 ? -15.248  -96.760  -23.198 1.00 34.13  ? 234  VAL C CA    1 
ATOM   8459  C C     . VAL C 1 234 ? -16.514  -96.493  -22.377 1.00 34.12  ? 234  VAL C C     1 
ATOM   8460  O O     . VAL C 1 234 ? -17.129  -95.420  -22.480 1.00 29.49  ? 234  VAL C O     1 
ATOM   8461  C CB    . VAL C 1 234 ? -14.071  -95.863  -22.740 1.00 37.78  ? 234  VAL C CB    1 
ATOM   8462  C CG1   . VAL C 1 234 ? -13.747  -96.064  -21.266 1.00 36.42  ? 234  VAL C CG1   1 
ATOM   8463  C CG2   . VAL C 1 234 ? -12.825  -96.135  -23.580 1.00 35.27  ? 234  VAL C CG2   1 
ATOM   8464  N N     . ALA C 1 235 ? -16.916  -97.481  -21.571 1.00 28.22  ? 235  ALA C N     1 
ATOM   8465  C CA    . ALA C 1 235 ? -18.082  -97.343  -20.707 1.00 26.18  ? 235  ALA C CA    1 
ATOM   8466  C C     . ALA C 1 235 ? -17.721  -96.542  -19.448 1.00 27.86  ? 235  ALA C C     1 
ATOM   8467  O O     . ALA C 1 235 ? -16.552  -96.159  -19.257 1.00 28.37  ? 235  ALA C O     1 
ATOM   8468  C CB    . ALA C 1 235 ? -18.608  -98.720  -20.368 1.00 21.60  ? 235  ALA C CB    1 
ATOM   8469  N N     . GLY C 1 236 ? -18.725  -96.301  -18.575 1.00 26.17  ? 236  GLY C N     1 
ATOM   8470  C CA    . GLY C 1 236 ? -18.517  -95.564  -17.332 1.00 27.27  ? 236  GLY C CA    1 
ATOM   8471  C C     . GLY C 1 236 ? -19.183  -96.236  -16.131 1.00 25.28  ? 236  GLY C C     1 
ATOM   8472  O O     . GLY C 1 236 ? -20.112  -97.021  -16.301 1.00 27.15  ? 236  GLY C O     1 
ATOM   8473  N N     . GLU C 1 237 ? -18.721  -95.930  -14.910 1.00 25.44  ? 237  GLU C N     1 
ATOM   8474  C CA    . GLU C 1 237 ? -19.275  -96.543  -13.707 1.00 23.99  ? 237  GLU C CA    1 
ATOM   8475  C C     . GLU C 1 237 ? -19.186  -95.543  -12.555 1.00 28.03  ? 237  GLU C C     1 
ATOM   8476  O O     . GLU C 1 237 ? -18.187  -94.833  -12.454 1.00 30.73  ? 237  GLU C O     1 
ATOM   8477  C CB    . GLU C 1 237 ? -18.454  -97.780  -13.369 1.00 22.85  ? 237  GLU C CB    1 
ATOM   8478  C CG    . GLU C 1 237 ? -19.090  -98.693  -12.320 1.00 27.56  ? 237  GLU C CG    1 
ATOM   8479  C CD    . GLU C 1 237 ? -18.144  -99.817  -11.916 1.00 36.28  ? 237  GLU C CD    1 
ATOM   8480  O OE1   . GLU C 1 237 ? -18.352  -101.022 -12.266 1.00 38.00  ? 237  GLU C OE1   1 
ATOM   8481  O OE2   . GLU C 1 237 ? -17.162  -99.442  -11.221 1.00 39.84  ? 237  GLU C OE2   1 
ATOM   8482  N N     . ILE C 1 238 ? -20.225  -95.474  -11.710 1.00 24.81  ? 238  ILE C N     1 
ATOM   8483  C CA    . ILE C 1 238 ? -20.143  -94.706  -10.478 1.00 22.74  ? 238  ILE C CA    1 
ATOM   8484  C C     . ILE C 1 238 ? -20.312  -95.661  -9.299  1.00 24.24  ? 238  ILE C C     1 
ATOM   8485  O O     . ILE C 1 238 ? -20.774  -96.799  -9.467  1.00 27.72  ? 238  ILE C O     1 
ATOM   8486  C CB    . ILE C 1 238 ? -21.158  -93.538  -10.450 1.00 21.13  ? 238  ILE C CB    1 
ATOM   8487  C CG1   . ILE C 1 238 ? -22.571  -94.021  -10.319 1.00 23.63  ? 238  ILE C CG1   1 
ATOM   8488  C CG2   . ILE C 1 238 ? -21.031  -92.623  -11.665 1.00 19.83  ? 238  ILE C CG2   1 
ATOM   8489  C CD1   . ILE C 1 238 ? -23.573  -92.889  -10.294 1.00 26.62  ? 238  ILE C CD1   1 
ATOM   8490  N N     . SER C 1 239 ? -19.961  -95.177  -8.100  1.00 23.38  ? 239  SER C N     1 
ATOM   8491  C CA    . SER C 1 239 ? -19.896  -95.962  -6.875  1.00 26.90  ? 239  SER C CA    1 
ATOM   8492  C C     . SER C 1 239 ? -20.579  -95.198  -5.746  1.00 30.26  ? 239  SER C C     1 
ATOM   8493  O O     . SER C 1 239 ? -20.424  -93.972  -5.651  1.00 26.00  ? 239  SER C O     1 
ATOM   8494  C CB    . SER C 1 239 ? -18.462  -96.145  -6.479  1.00 28.52  ? 239  SER C CB    1 
ATOM   8495  O OG    . SER C 1 239 ? -18.001  -97.286  -7.172  1.00 41.98  ? 239  SER C OG    1 
ATOM   8496  N N     . ILE C 1 240 ? -21.256  -95.925  -4.844  1.00 25.75  ? 240  ILE C N     1 
ATOM   8497  C CA    . ILE C 1 240 ? -21.758  -95.274  -3.654  1.00 22.94  ? 240  ILE C CA    1 
ATOM   8498  C C     . ILE C 1 240 ? -21.456  -96.188  -2.475  1.00 23.15  ? 240  ILE C C     1 
ATOM   8499  O O     . ILE C 1 240 ? -21.652  -97.401  -2.560  1.00 25.41  ? 240  ILE C O     1 
ATOM   8500  C CB    . ILE C 1 240 ? -23.260  -94.919  -3.793  1.00 25.59  ? 240  ILE C CB    1 
ATOM   8501  C CG1   . ILE C 1 240 ? -23.745  -94.086  -2.604  1.00 23.39  ? 240  ILE C CG1   1 
ATOM   8502  C CG2   . ILE C 1 240 ? -24.160  -96.154  -4.021  1.00 21.23  ? 240  ILE C CG2   1 
ATOM   8503  C CD1   . ILE C 1 240 ? -25.222  -93.734  -2.658  1.00 26.42  ? 240  ILE C CD1   1 
ATOM   8504  N N     . THR C 1 241 ? -20.963  -95.608  -1.377  1.00 21.13  ? 241  THR C N     1 
ATOM   8505  C CA    . THR C 1 241 ? -20.873  -96.349  -0.138  1.00 20.08  ? 241  THR C CA    1 
ATOM   8506  C C     . THR C 1 241 ? -21.975  -95.859  0.809   1.00 18.88  ? 241  THR C C     1 
ATOM   8507  O O     . THR C 1 241 ? -22.455  -94.739  0.661   1.00 20.90  ? 241  THR C O     1 
ATOM   8508  C CB    . THR C 1 241 ? -19.455  -96.237  0.425   1.00 22.95  ? 241  THR C CB    1 
ATOM   8509  O OG1   . THR C 1 241 ? -19.390  -97.263  1.438   1.00 24.54  ? 241  THR C OG1   1 
ATOM   8510  C CG2   . THR C 1 241 ? -19.112  -94.828  0.897   1.00 21.65  ? 241  THR C CG2   1 
ATOM   8511  N N     . LEU C 1 242 ? -22.383  -96.688  1.775   1.00 20.77  ? 242  LEU C N     1 
ATOM   8512  C CA    . LEU C 1 242 ? -23.567  -96.407  2.585   1.00 22.93  ? 242  LEU C CA    1 
ATOM   8513  C C     . LEU C 1 242 ? -23.332  -95.294  3.602   1.00 22.60  ? 242  LEU C C     1 
ATOM   8514  O O     . LEU C 1 242 ? -24.222  -94.479  3.855   1.00 25.31  ? 242  LEU C O     1 
ATOM   8515  C CB    . LEU C 1 242 ? -24.112  -97.670  3.241   1.00 22.89  ? 242  LEU C CB    1 
ATOM   8516  C CG    . LEU C 1 242 ? -24.531  -98.769  2.233   1.00 26.08  ? 242  LEU C CG    1 
ATOM   8517  C CD1   . LEU C 1 242 ? -24.994  -100.032 2.977   1.00 21.39  ? 242  LEU C CD1   1 
ATOM   8518  C CD2   . LEU C 1 242 ? -25.557  -98.317  1.174   1.00 21.97  ? 242  LEU C CD2   1 
ATOM   8519  N N     . ASN C 1 243 ? -22.144  -95.272  4.208   1.00 21.97  ? 243  ASN C N     1 
ATOM   8520  C CA    . ASN C 1 243 ? -21.758  -94.185  5.102   1.00 21.74  ? 243  ASN C CA    1 
ATOM   8521  C C     . ASN C 1 243 ? -20.568  -93.471  4.465   1.00 20.92  ? 243  ASN C C     1 
ATOM   8522  O O     . ASN C 1 243 ? -20.535  -93.341  3.253   1.00 24.40  ? 243  ASN C O     1 
ATOM   8523  C CB    . ASN C 1 243 ? -21.628  -94.647  6.552   1.00 18.95  ? 243  ASN C CB    1 
ATOM   8524  C CG    . ASN C 1 243 ? -20.640  -95.786  6.719   1.00 22.40  ? 243  ASN C CG    1 
ATOM   8525  O OD1   . ASN C 1 243 ? -19.858  -96.073  5.800   1.00 21.49  ? 243  ASN C OD1   1 
ATOM   8526  N ND2   . ASN C 1 243 ? -20.626  -96.430  7.886   1.00 20.85  ? 243  ASN C ND2   1 
ATOM   8527  N N     . GLN C 1 244 ? -19.591  -93.044  5.264   1.00 20.94  ? 244  GLN C N     1 
ATOM   8528  C CA    . GLN C 1 244 ? -18.480  -92.269  4.741   1.00 21.20  ? 244  GLN C CA    1 
ATOM   8529  C C     . GLN C 1 244 ? -17.292  -93.175  4.385   1.00 22.45  ? 244  GLN C C     1 
ATOM   8530  O O     . GLN C 1 244 ? -16.323  -92.704  3.778   1.00 22.80  ? 244  GLN C O     1 
ATOM   8531  C CB    . GLN C 1 244 ? -18.059  -91.234  5.782   1.00 21.78  ? 244  GLN C CB    1 
ATOM   8532  C CG    . GLN C 1 244 ? -19.026  -90.068  5.949   1.00 24.58  ? 244  GLN C CG    1 
ATOM   8533  C CD    . GLN C 1 244 ? -19.093  -89.240  4.693   1.00 27.52  ? 244  GLN C CD    1 
ATOM   8534  O OE1   . GLN C 1 244 ? -18.099  -88.625  4.296   1.00 32.74  ? 244  GLN C OE1   1 
ATOM   8535  N NE2   . GLN C 1 244 ? -20.240  -89.265  4.034   1.00 24.70  ? 244  GLN C NE2   1 
ATOM   8536  N N     . HIS C 1 245 ? -17.346  -94.464  4.758   1.00 21.87  ? 245  HIS C N     1 
ATOM   8537  C CA    . HIS C 1 245 ? -16.192  -95.348  4.635   1.00 21.67  ? 245  HIS C CA    1 
ATOM   8538  C C     . HIS C 1 245 ? -16.526  -96.525  3.716   1.00 21.27  ? 245  HIS C C     1 
ATOM   8539  O O     . HIS C 1 245 ? -17.670  -96.883  3.566   1.00 22.11  ? 245  HIS C O     1 
ATOM   8540  C CB    . HIS C 1 245 ? -15.729  -95.797  6.021   1.00 18.84  ? 245  HIS C CB    1 
ATOM   8541  C CG    . HIS C 1 245 ? -15.292  -94.660  6.862   1.00 21.33  ? 245  HIS C CG    1 
ATOM   8542  N ND1   . HIS C 1 245 ? -16.183  -93.886  7.582   1.00 21.17  ? 245  HIS C ND1   1 
ATOM   8543  C CD2   . HIS C 1 245 ? -14.074  -94.103  7.069   1.00 22.02  ? 245  HIS C CD2   1 
ATOM   8544  C CE1   . HIS C 1 245 ? -15.519  -92.911  8.207   1.00 22.17  ? 245  HIS C CE1   1 
ATOM   8545  N NE2   . HIS C 1 245 ? -14.243  -93.022  7.914   1.00 21.03  ? 245  HIS C NE2   1 
ATOM   8546  N N     . TRP C 1 246 ? -15.511  -97.135  3.116   1.00 21.74  ? 246  TRP C N     1 
ATOM   8547  C CA    . TRP C 1 246 ? -15.674  -98.293  2.248   1.00 21.46  ? 246  TRP C CA    1 
ATOM   8548  C C     . TRP C 1 246 ? -15.544  -99.583  3.048   1.00 20.81  ? 246  TRP C C     1 
ATOM   8549  O O     . TRP C 1 246 ? -16.392  -100.460 2.907   1.00 22.56  ? 246  TRP C O     1 
ATOM   8550  C CB    . TRP C 1 246 ? -14.688  -98.225  1.073   1.00 22.83  ? 246  TRP C CB    1 
ATOM   8551  C CG    . TRP C 1 246 ? -14.973  -96.996  0.252   1.00 25.19  ? 246  TRP C CG    1 
ATOM   8552  C CD1   . TRP C 1 246 ? -14.536  -95.729  0.524   1.00 25.87  ? 246  TRP C CD1   1 
ATOM   8553  C CD2   . TRP C 1 246 ? -15.819  -96.886  -0.912  1.00 25.15  ? 246  TRP C CD2   1 
ATOM   8554  N NE1   . TRP C 1 246 ? -15.049  -94.845  -0.387  1.00 25.54  ? 246  TRP C NE1   1 
ATOM   8555  C CE2   . TRP C 1 246 ? -15.821  -95.515  -1.295  1.00 29.25  ? 246  TRP C CE2   1 
ATOM   8556  C CE3   . TRP C 1 246 ? -16.556  -97.793  -1.683  1.00 22.18  ? 246  TRP C CE3   1 
ATOM   8557  C CZ2   . TRP C 1 246 ? -16.553  -95.028  -2.391  1.00 24.61  ? 246  TRP C CZ2   1 
ATOM   8558  C CZ3   . TRP C 1 246 ? -17.258  -97.328  -2.774  1.00 20.42  ? 246  TRP C CZ3   1 
ATOM   8559  C CH2   . TRP C 1 246 ? -17.266  -95.963  -3.109  1.00 23.97  ? 246  TRP C CH2   1 
ATOM   8560  N N     . GLY C 1 247 ? -14.479  -99.726  3.857   1.00 19.10  ? 247  GLY C N     1 
ATOM   8561  C CA    . GLY C 1 247 ? -14.424  -100.815 4.822   1.00 17.05  ? 247  GLY C CA    1 
ATOM   8562  C C     . GLY C 1 247 ? -15.387  -100.491 5.966   1.00 19.26  ? 247  GLY C C     1 
ATOM   8563  O O     . GLY C 1 247 ? -15.790  -99.341  6.119   1.00 18.46  ? 247  GLY C O     1 
ATOM   8564  N N     . ILE C 1 248 ? -15.750  -101.493 6.781   1.00 20.14  ? 248  ILE C N     1 
ATOM   8565  C CA    . ILE C 1 248 ? -16.653  -101.297 7.888   1.00 19.97  ? 248  ILE C CA    1 
ATOM   8566  C C     . ILE C 1 248 ? -16.063  -100.280 8.884   1.00 23.57  ? 248  ILE C C     1 
ATOM   8567  O O     . ILE C 1 248 ? -14.849  -100.196 9.109   1.00 24.90  ? 248  ILE C O     1 
ATOM   8568  C CB    . ILE C 1 248 ? -16.917  -102.662 8.538   1.00 19.81  ? 248  ILE C CB    1 
ATOM   8569  C CG1   . ILE C 1 248 ? -18.052  -102.594 9.596   1.00 20.56  ? 248  ILE C CG1   1 
ATOM   8570  C CG2   . ILE C 1 248 ? -15.633  -103.256 9.137   1.00 19.06  ? 248  ILE C CG2   1 
ATOM   8571  C CD1   . ILE C 1 248 ? -18.602  -103.960 9.968   1.00 19.36  ? 248  ILE C CD1   1 
ATOM   8572  N N     . ALA C 1 249 ? -16.947  -99.483  9.485   1.00 23.52  ? 249  ALA C N     1 
ATOM   8573  C CA    . ALA C 1 249 ? -16.587  -98.410  10.408  1.00 20.18  ? 249  ALA C CA    1 
ATOM   8574  C C     . ALA C 1 249 ? -17.737  -98.272  11.408  1.00 23.90  ? 249  ALA C C     1 
ATOM   8575  O O     . ALA C 1 249 ? -18.762  -97.637  11.118  1.00 21.84  ? 249  ALA C O     1 
ATOM   8576  C CB    . ALA C 1 249 ? -16.369  -97.140  9.625   1.00 19.79  ? 249  ALA C CB    1 
ATOM   8577  N N     . ALA C 1 250 ? -17.552  -98.901  12.572  1.00 22.54  ? 250  ALA C N     1 
ATOM   8578  C CA    . ALA C 1 250 ? -18.598  -99.139  13.545  1.00 22.25  ? 250  ALA C CA    1 
ATOM   8579  C C     . ALA C 1 250 ? -19.198  -97.829  14.057  1.00 22.02  ? 250  ALA C C     1 
ATOM   8580  O O     . ALA C 1 250 ? -20.381  -97.784  14.338  1.00 23.36  ? 250  ALA C O     1 
ATOM   8581  C CB    . ALA C 1 250 ? -18.036  -99.980  14.722  1.00 20.58  ? 250  ALA C CB    1 
ATOM   8582  N N     . ASN C 1 251 ? -18.388  -96.791  14.250  1.00 21.84  ? 251  ASN C N     1 
ATOM   8583  C CA    . ASN C 1 251 ? -18.899  -95.530  14.772  1.00 20.70  ? 251  ASN C CA    1 
ATOM   8584  C C     . ASN C 1 251 ? -19.036  -94.467  13.685  1.00 21.39  ? 251  ASN C C     1 
ATOM   8585  O O     . ASN C 1 251 ? -19.006  -93.268  13.974  1.00 21.08  ? 251  ASN C O     1 
ATOM   8586  C CB    . ASN C 1 251 ? -18.080  -95.029  15.947  1.00 20.45  ? 251  ASN C CB    1 
ATOM   8587  C CG    . ASN C 1 251 ? -18.227  -95.937  17.137  1.00 24.82  ? 251  ASN C CG    1 
ATOM   8588  O OD1   . ASN C 1 251 ? -19.325  -96.414  17.488  1.00 28.07  ? 251  ASN C OD1   1 
ATOM   8589  N ND2   . ASN C 1 251 ? -17.097  -96.182  17.756  1.00 26.06  ? 251  ASN C ND2   1 
ATOM   8590  N N     . ASP C 1 252 ? -19.176  -94.910  12.430  1.00 22.99  ? 252  ASP C N     1 
ATOM   8591  C CA    . ASP C 1 252 ? -19.610  -94.012  11.366  1.00 23.14  ? 252  ASP C CA    1 
ATOM   8592  C C     . ASP C 1 252 ? -21.134  -94.145  11.280  1.00 21.80  ? 252  ASP C C     1 
ATOM   8593  O O     . ASP C 1 252 ? -21.626  -95.135  10.719  1.00 22.00  ? 252  ASP C O     1 
ATOM   8594  C CB    . ASP C 1 252 ? -18.879  -94.291  10.058  1.00 19.05  ? 252  ASP C CB    1 
ATOM   8595  C CG    . ASP C 1 252 ? -19.381  -93.484  8.872   1.00 22.44  ? 252  ASP C CG    1 
ATOM   8596  O OD1   . ASP C 1 252 ? -20.336  -92.695  9.069   1.00 23.59  ? 252  ASP C OD1   1 
ATOM   8597  O OD2   . ASP C 1 252 ? -18.813  -93.611  7.745   1.00 23.59  ? 252  ASP C OD2   1 
ATOM   8598  N N     . LEU C 1 253 ? -21.859  -93.168  11.870  1.00 19.19  ? 253  LEU C N     1 
ATOM   8599  C CA    . LEU C 1 253 ? -23.315  -93.192  11.915  1.00 18.90  ? 253  LEU C CA    1 
ATOM   8600  C C     . LEU C 1 253 ? -23.861  -92.379  10.741  1.00 21.41  ? 253  LEU C C     1 
ATOM   8601  O O     . LEU C 1 253 ? -25.077  -92.226  10.600  1.00 21.04  ? 253  LEU C O     1 
ATOM   8602  C CB    . LEU C 1 253 ? -23.798  -92.600  13.243  1.00 16.61  ? 253  LEU C CB    1 
ATOM   8603  C CG    . LEU C 1 253 ? -23.097  -93.113  14.501  1.00 17.92  ? 253  LEU C CG    1 
ATOM   8604  C CD1   . LEU C 1 253 ? -23.675  -92.576  15.776  1.00 16.01  ? 253  LEU C CD1   1 
ATOM   8605  C CD2   . LEU C 1 253 ? -23.036  -94.668  14.520  1.00 17.50  ? 253  LEU C CD2   1 
ATOM   8606  N N     . ASN C 1 254 ? -22.969  -91.787  9.934   1.00 19.21  ? 254  ASN C N     1 
ATOM   8607  C CA    . ASN C 1 254 ? -23.417  -90.851  8.907   1.00 19.57  ? 254  ASN C CA    1 
ATOM   8608  C C     . ASN C 1 254 ? -23.857  -91.604  7.639   1.00 21.43  ? 254  ASN C C     1 
ATOM   8609  O O     . ASN C 1 254 ? -23.255  -91.460  6.574   1.00 21.58  ? 254  ASN C O     1 
ATOM   8610  C CB    . ASN C 1 254 ? -22.322  -89.825  8.666   1.00 18.72  ? 254  ASN C CB    1 
ATOM   8611  C CG    . ASN C 1 254 ? -22.762  -88.706  7.760   1.00 23.30  ? 254  ASN C CG    1 
ATOM   8612  O OD1   . ASN C 1 254 ? -23.955  -88.536  7.512   1.00 23.97  ? 254  ASN C OD1   1 
ATOM   8613  N ND2   . ASN C 1 254 ? -21.826  -87.929  7.236   1.00 22.34  ? 254  ASN C ND2   1 
ATOM   8614  N N     . TYR C 1 255 ? -24.893  -92.449  7.755   1.00 22.58  ? 255  TYR C N     1 
ATOM   8615  C CA    . TYR C 1 255 ? -25.428  -93.216  6.635   1.00 22.78  ? 255  TYR C CA    1 
ATOM   8616  C C     . TYR C 1 255 ? -26.291  -92.321  5.758   1.00 21.55  ? 255  TYR C C     1 
ATOM   8617  O O     . TYR C 1 255 ? -26.983  -91.445  6.278   1.00 23.69  ? 255  TYR C O     1 
ATOM   8618  C CB    . TYR C 1 255 ? -26.295  -94.350  7.194   1.00 21.43  ? 255  TYR C CB    1 
ATOM   8619  C CG    . TYR C 1 255 ? -25.481  -95.578  7.564   1.00 22.44  ? 255  TYR C CG    1 
ATOM   8620  C CD1   . TYR C 1 255 ? -24.735  -95.615  8.740   1.00 22.47  ? 255  TYR C CD1   1 
ATOM   8621  C CD2   . TYR C 1 255 ? -25.434  -96.681  6.723   1.00 23.93  ? 255  TYR C CD2   1 
ATOM   8622  C CE1   . TYR C 1 255 ? -23.984  -96.723  9.083   1.00 19.90  ? 255  TYR C CE1   1 
ATOM   8623  C CE2   . TYR C 1 255 ? -24.683  -97.802  7.039   1.00 23.75  ? 255  TYR C CE2   1 
ATOM   8624  C CZ    . TYR C 1 255 ? -23.947  -97.801  8.212   1.00 25.21  ? 255  TYR C CZ    1 
ATOM   8625  O OH    . TYR C 1 255 ? -23.215  -98.906  8.499   1.00 25.99  ? 255  TYR C OH    1 
ATOM   8626  N N     . LYS C 1 256 ? -26.245  -92.553  4.442   1.00 21.08  ? 256  LYS C N     1 
ATOM   8627  C CA    . LYS C 1 256 ? -27.135  -91.889  3.497   1.00 19.49  ? 256  LYS C CA    1 
ATOM   8628  C C     . LYS C 1 256 ? -28.518  -92.512  3.634   1.00 20.85  ? 256  LYS C C     1 
ATOM   8629  O O     . LYS C 1 256 ? -28.649  -93.636  4.142   1.00 23.90  ? 256  LYS C O     1 
ATOM   8630  C CB    . LYS C 1 256 ? -26.574  -92.135  2.096   1.00 20.68  ? 256  LYS C CB    1 
ATOM   8631  C CG    . LYS C 1 256 ? -25.186  -91.548  1.888   1.00 23.59  ? 256  LYS C CG    1 
ATOM   8632  C CD    . LYS C 1 256 ? -24.560  -91.980  0.562   1.00 24.90  ? 256  LYS C CD    1 
ATOM   8633  C CE    . LYS C 1 256 ? -23.131  -91.499  0.424   1.00 24.33  ? 256  LYS C CE    1 
ATOM   8634  N NZ    . LYS C 1 256 ? -22.302  -92.009  1.514   1.00 21.51  ? 256  LYS C NZ    1 
ATOM   8635  N N     . SER C 1 257 ? -29.563  -91.795  3.203   1.00 18.02  ? 257  SER C N     1 
ATOM   8636  C CA    . SER C 1 257 ? -30.886  -92.403  3.250   1.00 20.25  ? 257  SER C CA    1 
ATOM   8637  C C     . SER C 1 257 ? -31.003  -93.483  2.171   1.00 20.61  ? 257  SER C C     1 
ATOM   8638  O O     . SER C 1 257 ? -30.392  -93.374  1.100   1.00 18.11  ? 257  SER C O     1 
ATOM   8639  C CB    . SER C 1 257 ? -31.974  -91.372  3.039   1.00 20.62  ? 257  SER C CB    1 
ATOM   8640  O OG    . SER C 1 257 ? -31.906  -90.881  1.708   1.00 23.13  ? 257  SER C OG    1 
ATOM   8641  N N     . PRO C 1 258 ? -31.811  -94.533  2.414   1.00 21.24  ? 258  PRO C N     1 
ATOM   8642  C CA    . PRO C 1 258 ? -32.184  -95.467  1.344   1.00 21.68  ? 258  PRO C CA    1 
ATOM   8643  C C     . PRO C 1 258 ? -32.724  -94.741  0.112   1.00 23.59  ? 258  PRO C C     1 
ATOM   8644  O O     . PRO C 1 258 ? -32.462  -95.152  -1.014  1.00 24.53  ? 258  PRO C O     1 
ATOM   8645  C CB    . PRO C 1 258 ? -33.140  -96.448  2.041   1.00 19.88  ? 258  PRO C CB    1 
ATOM   8646  C CG    . PRO C 1 258 ? -32.705  -96.376  3.521   1.00 19.66  ? 258  PRO C CG    1 
ATOM   8647  C CD    . PRO C 1 258 ? -32.312  -94.925  3.745   1.00 19.72  ? 258  PRO C CD    1 
ATOM   8648  N N     . ALA C 1 259 ? -33.413  -93.604  0.312   1.00 21.36  ? 259  ALA C N     1 
ATOM   8649  C CA    . ALA C 1 259 ? -33.940  -92.853  -0.829  1.00 21.14  ? 259  ALA C CA    1 
ATOM   8650  C C     . ALA C 1 259 ? -32.800  -92.330  -1.708  1.00 24.46  ? 259  ALA C C     1 
ATOM   8651  O O     . ALA C 1 259 ? -32.878  -92.401  -2.929  1.00 25.27  ? 259  ALA C O     1 
ATOM   8652  C CB    . ALA C 1 259 ? -34.830  -91.726  -0.356  1.00 18.90  ? 259  ALA C CB    1 
ATOM   8653  N N     . GLU C 1 260 ? -31.739  -91.802  -1.077  1.00 24.77  ? 260  GLU C N     1 
ATOM   8654  C CA    . GLU C 1 260 ? -30.615  -91.279  -1.820  1.00 26.27  ? 260  GLU C CA    1 
ATOM   8655  C C     . GLU C 1 260 ? -29.940  -92.428  -2.589  1.00 25.71  ? 260  GLU C C     1 
ATOM   8656  O O     . GLU C 1 260 ? -29.511  -92.261  -3.736  1.00 26.97  ? 260  GLU C O     1 
ATOM   8657  C CB    . GLU C 1 260 ? -29.655  -90.512  -0.915  1.00 30.94  ? 260  GLU C CB    1 
ATOM   8658  C CG    . GLU C 1 260 ? -28.382  -90.090  -1.664  1.00 32.69  ? 260  GLU C CG    1 
ATOM   8659  C CD    . GLU C 1 260 ? -27.349  -89.247  -0.919  1.00 38.23  ? 260  GLU C CD    1 
ATOM   8660  O OE1   . GLU C 1 260 ? -27.607  -88.856  0.244   1.00 42.96  ? 260  GLU C OE1   1 
ATOM   8661  O OE2   . GLU C 1 260 ? -26.260  -88.976  -1.477  1.00 39.40  ? 260  GLU C OE2   1 
ATOM   8662  N N     . MET C 1 261 ? -29.874  -93.601  -1.969  1.00 22.49  ? 261  MET C N     1 
ATOM   8663  C CA    . MET C 1 261 ? -29.332  -94.776  -2.631  1.00 22.80  ? 261  MET C CA    1 
ATOM   8664  C C     . MET C 1 261 ? -30.128  -95.092  -3.908  1.00 22.82  ? 261  MET C C     1 
ATOM   8665  O O     . MET C 1 261 ? -29.531  -95.257  -4.987  1.00 23.57  ? 261  MET C O     1 
ATOM   8666  C CB    . MET C 1 261 ? -29.307  -95.966  -1.659  1.00 21.86  ? 261  MET C CB    1 
ATOM   8667  C CG    . MET C 1 261 ? -28.937  -97.294  -2.335  1.00 21.37  ? 261  MET C CG    1 
ATOM   8668  S SD    . MET C 1 261 ? -29.106  -98.725  -1.238  1.00 29.09  ? 261  MET C SD    1 
ATOM   8669  C CE    . MET C 1 261 ? -30.876  -98.667  -0.849  1.00 24.96  ? 261  MET C CE    1 
ATOM   8670  N N     . ILE C 1 262 ? -31.474  -95.117  -3.804  1.00 19.36  ? 262  ILE C N     1 
ATOM   8671  C CA    . ILE C 1 262 ? -32.300  -95.399  -4.962  1.00 19.63  ? 262  ILE C CA    1 
ATOM   8672  C C     . ILE C 1 262 ? -32.102  -94.334  -6.032  1.00 21.77  ? 262  ILE C C     1 
ATOM   8673  O O     . ILE C 1 262 ? -31.933  -94.667  -7.208  1.00 20.74  ? 262  ILE C O     1 
ATOM   8674  C CB    . ILE C 1 262 ? -33.771  -95.602  -4.573  1.00 18.96  ? 262  ILE C CB    1 
ATOM   8675  C CG1   . ILE C 1 262 ? -33.890  -96.952  -3.843  1.00 18.18  ? 262  ILE C CG1   1 
ATOM   8676  C CG2   . ILE C 1 262 ? -34.676  -95.580  -5.804  1.00 15.23  ? 262  ILE C CG2   1 
ATOM   8677  C CD1   . ILE C 1 262 ? -35.151  -97.099  -3.026  1.00 16.53  ? 262  ILE C CD1   1 
ATOM   8678  N N     . GLU C 1 263 ? -32.092  -93.054  -5.625  1.00 21.01  ? 263  GLU C N     1 
ATOM   8679  C CA    . GLU C 1 263 ? -31.892  -91.983  -6.590  1.00 22.35  ? 263  GLU C CA    1 
ATOM   8680  C C     . GLU C 1 263 ? -30.539  -92.114  -7.303  1.00 24.02  ? 263  GLU C C     1 
ATOM   8681  O O     . GLU C 1 263 ? -30.454  -91.752  -8.479  1.00 24.27  ? 263  GLU C O     1 
ATOM   8682  C CB    . GLU C 1 263 ? -32.036  -90.599  -5.964  1.00 24.39  ? 263  GLU C CB    1 
ATOM   8683  C CG    . GLU C 1 263 ? -33.469  -90.294  -5.534  1.00 31.92  ? 263  GLU C CG    1 
ATOM   8684  C CD    . GLU C 1 263 ? -33.768  -88.864  -5.102  1.00 39.48  ? 263  GLU C CD    1 
ATOM   8685  O OE1   . GLU C 1 263 ? -32.830  -88.059  -5.212  1.00 39.57  ? 263  GLU C OE1   1 
ATOM   8686  O OE2   . GLU C 1 263 ? -34.910  -88.515  -4.687  1.00 42.47  ? 263  GLU C OE2   1 
ATOM   8687  N N     . THR C 1 264 ? -29.503  -92.629  -6.609  1.00 19.52  ? 264  THR C N     1 
ATOM   8688  C CA    . THR C 1 264 ? -28.175  -92.686  -7.200  1.00 20.25  ? 264  THR C CA    1 
ATOM   8689  C C     . THR C 1 264 ? -28.148  -93.806  -8.237  1.00 21.84  ? 264  THR C C     1 
ATOM   8690  O O     . THR C 1 264 ? -27.548  -93.640  -9.310  1.00 20.20  ? 264  THR C O     1 
ATOM   8691  C CB    . THR C 1 264 ? -27.090  -92.877  -6.136  1.00 22.13  ? 264  THR C CB    1 
ATOM   8692  O OG1   . THR C 1 264 ? -27.286  -91.803  -5.216  1.00 22.95  ? 264  THR C OG1   1 
ATOM   8693  C CG2   . THR C 1 264 ? -25.687  -92.749  -6.699  1.00 17.60  ? 264  THR C CG2   1 
ATOM   8694  N N     . VAL C 1 265 ? -28.805  -94.937  -7.922  1.00 18.88  ? 265  VAL C N     1 
ATOM   8695  C CA    . VAL C 1 265 ? -28.889  -96.020  -8.887  1.00 16.95  ? 265  VAL C CA    1 
ATOM   8696  C C     . VAL C 1 265 ? -29.601  -95.520  -10.146 1.00 20.66  ? 265  VAL C C     1 
ATOM   8697  O O     . VAL C 1 265 ? -29.106  -95.699  -11.257 1.00 24.86  ? 265  VAL C O     1 
ATOM   8698  C CB    . VAL C 1 265 ? -29.602  -97.239  -8.279  1.00 17.60  ? 265  VAL C CB    1 
ATOM   8699  C CG1   . VAL C 1 265 ? -29.967  -98.282  -9.336  1.00 16.23  ? 265  VAL C CG1   1 
ATOM   8700  C CG2   . VAL C 1 265 ? -28.812  -97.839  -7.118  1.00 15.76  ? 265  VAL C CG2   1 
ATOM   8701  N N     . ALA C 1 266 ? -30.746  -94.838  -9.988  1.00 21.03  ? 266  ALA C N     1 
ATOM   8702  C CA    . ALA C 1 266 ? -31.468  -94.348  -11.154 1.00 21.30  ? 266  ALA C CA    1 
ATOM   8703  C C     . ALA C 1 266 ? -30.594  -93.361  -11.929 1.00 21.27  ? 266  ALA C C     1 
ATOM   8704  O O     . ALA C 1 266 ? -30.565  -93.356  -13.172 1.00 20.83  ? 266  ALA C O     1 
ATOM   8705  C CB    . ALA C 1 266 ? -32.778  -93.710  -10.748 1.00 20.11  ? 266  ALA C CB    1 
ATOM   8706  N N     . HIS C 1 267 ? -29.890  -92.528  -11.203 1.00 21.38  ? 267  HIS C N     1 
ATOM   8707  C CA    . HIS C 1 267 ? -29.040  -91.524  -11.767 1.00 21.32  ? 267  HIS C CA    1 
ATOM   8708  C C     . HIS C 1 267 ? -27.913  -92.062  -12.616 1.00 20.98  ? 267  HIS C C     1 
ATOM   8709  O O     . HIS C 1 267 ? -27.581  -91.466  -13.575 1.00 23.30  ? 267  HIS C O     1 
ATOM   8710  C CB    . HIS C 1 267 ? -28.537  -90.588  -10.695 1.00 19.19  ? 267  HIS C CB    1 
ATOM   8711  C CG    . HIS C 1 267 ? -27.597  -89.556  -11.199 1.00 23.44  ? 267  HIS C CG    1 
ATOM   8712  N ND1   . HIS C 1 267 ? -28.007  -88.480  -11.942 1.00 22.07  ? 267  HIS C ND1   1 
ATOM   8713  C CD2   . HIS C 1 267 ? -26.261  -89.452  -11.102 1.00 20.63  ? 267  HIS C CD2   1 
ATOM   8714  C CE1   . HIS C 1 267 ? -26.968  -87.757  -12.274 1.00 21.09  ? 267  HIS C CE1   1 
ATOM   8715  N NE2   . HIS C 1 267 ? -25.898  -88.320  -11.769 1.00 21.66  ? 267  HIS C NE2   1 
ATOM   8716  N N     . ALA C 1 268 ? -27.331  -93.189  -12.255 1.00 21.25  ? 268  ALA C N     1 
ATOM   8717  C CA    . ALA C 1 268 ? -26.261  -93.764  -13.012 1.00 23.91  ? 268  ALA C CA    1 
ATOM   8718  C C     . ALA C 1 268 ? -26.736  -94.119  -14.401 1.00 26.53  ? 268  ALA C C     1 
ATOM   8719  O O     . ALA C 1 268 ? -26.084  -93.825  -15.348 1.00 21.79  ? 268  ALA C O     1 
ATOM   8720  C CB    . ALA C 1 268 ? -25.719  -94.990  -12.320 1.00 22.72  ? 268  ALA C CB    1 
ATOM   8721  N N     . ARG C 1 269 ? -27.913  -94.708  -14.475 1.00 22.27  ? 269  ARG C N     1 
ATOM   8722  C CA    . ARG C 1 269 ? -28.530  -95.106  -15.712 1.00 21.55  ? 269  ARG C CA    1 
ATOM   8723  C C     . ARG C 1 269 ? -28.850  -93.928  -16.576 1.00 24.11  ? 269  ARG C C     1 
ATOM   8724  O O     . ARG C 1 269 ? -28.708  -93.970  -17.748 1.00 23.28  ? 269  ARG C O     1 
ATOM   8725  C CB    . ARG C 1 269 ? -29.757  -95.948  -15.476 1.00 19.40  ? 269  ARG C CB    1 
ATOM   8726  C CG    . ARG C 1 269 ? -29.562  -97.049  -14.500 1.00 20.06  ? 269  ARG C CG    1 
ATOM   8727  C CD    . ARG C 1 269 ? -28.329  -97.843  -14.793 1.00 21.88  ? 269  ARG C CD    1 
ATOM   8728  N NE    . ARG C 1 269 ? -28.542  -98.811  -15.829 1.00 25.92  ? 269  ARG C NE    1 
ATOM   8729  C CZ    . ARG C 1 269 ? -27.603  -99.354  -16.572 1.00 26.11  ? 269  ARG C CZ    1 
ATOM   8730  N NH1   . ARG C 1 269 ? -26.359  -99.058  -16.430 1.00 28.38  ? 269  ARG C NH1   1 
ATOM   8731  N NH2   . ARG C 1 269 ? -27.925  -100.218 -17.454 1.00 22.92  ? 269  ARG C NH2   1 
ATOM   8732  N N     . HIS C 1 270 ? -29.295  -92.870  -15.955 1.00 24.78  ? 270  HIS C N     1 
ATOM   8733  C CA    . HIS C 1 270 ? -29.606  -91.665  -16.637 1.00 23.48  ? 270  HIS C CA    1 
ATOM   8734  C C     . HIS C 1 270 ? -28.390  -91.083  -17.316 1.00 25.66  ? 270  HIS C C     1 
ATOM   8735  O O     . HIS C 1 270 ? -28.505  -90.529  -18.336 1.00 29.23  ? 270  HIS C O     1 
ATOM   8736  C CB    . HIS C 1 270 ? -30.227  -90.680  -15.687 1.00 24.66  ? 270  HIS C CB    1 
ATOM   8737  C CG    . HIS C 1 270 ? -30.490  -89.351  -16.289 1.00 29.30  ? 270  HIS C CG    1 
ATOM   8738  N ND1   . HIS C 1 270 ? -30.236  -88.187  -15.628 1.00 35.60  ? 270  HIS C ND1   1 
ATOM   8739  C CD2   . HIS C 1 270 ? -31.019  -88.999  -17.473 1.00 27.41  ? 270  HIS C CD2   1 
ATOM   8740  C CE1   . HIS C 1 270 ? -30.581  -87.171  -16.381 1.00 31.34  ? 270  HIS C CE1   1 
ATOM   8741  N NE2   . HIS C 1 270 ? -31.059  -87.638  -17.507 1.00 32.13  ? 270  HIS C NE2   1 
ATOM   8742  N N     . ILE C 1 271 ? -27.217  -91.203  -16.733 1.00 28.12  ? 271  ILE C N     1 
ATOM   8743  C CA    . ILE C 1 271 ? -26.031  -90.620  -17.356 1.00 26.19  ? 271  ILE C CA    1 
ATOM   8744  C C     . ILE C 1 271 ? -25.290  -91.675  -18.174 1.00 23.68  ? 271  ILE C C     1 
ATOM   8745  O O     . ILE C 1 271 ? -24.280  -91.377  -18.750 1.00 32.67  ? 271  ILE C O     1 
ATOM   8746  C CB    . ILE C 1 271 ? -25.087  -89.938  -16.343 1.00 24.39  ? 271  ILE C CB    1 
ATOM   8747  C CG1   . ILE C 1 271 ? -24.509  -90.955  -15.344 1.00 23.33  ? 271  ILE C CG1   1 
ATOM   8748  C CG2   . ILE C 1 271 ? -25.798  -88.774  -15.641 1.00 22.63  ? 271  ILE C CG2   1 
ATOM   8749  C CD1   . ILE C 1 271 ? -23.461  -90.384  -14.401 1.00 21.90  ? 271  ILE C CD1   1 
ATOM   8750  N N     . GLY C 1 272 ? -25.799  -92.895  -18.255 1.00 22.14  ? 272  GLY C N     1 
ATOM   8751  C CA    . GLY C 1 272 ? -25.195  -93.918  -19.103 1.00 25.09  ? 272  GLY C CA    1 
ATOM   8752  C C     . GLY C 1 272 ? -24.032  -94.648  -18.434 1.00 27.45  ? 272  GLY C C     1 
ATOM   8753  O O     . GLY C 1 272 ? -23.036  -94.952  -19.095 1.00 32.85  ? 272  GLY C O     1 
ATOM   8754  N N     . ALA C 1 273 ? -24.180  -94.976  -17.140 1.00 22.94  ? 273  ALA C N     1 
ATOM   8755  C CA    . ALA C 1 273 ? -23.118  -95.619  -16.370 1.00 20.43  ? 273  ALA C CA    1 
ATOM   8756  C C     . ALA C 1 273 ? -23.699  -96.807  -15.624 1.00 21.97  ? 273  ALA C C     1 
ATOM   8757  O O     . ALA C 1 273 ? -24.912  -96.868  -15.417 1.00 21.65  ? 273  ALA C O     1 
ATOM   8758  C CB    . ALA C 1 273 ? -22.487  -94.623  -15.395 1.00 16.66  ? 273  ALA C CB    1 
ATOM   8759  N N     . ASN C 1 274 ? -22.828  -97.748  -15.234 1.00 20.52  ? 274  ASN C N     1 
ATOM   8760  C CA    . ASN C 1 274 ? -23.211  -98.728  -14.235 1.00 20.66  ? 274  ASN C CA    1 
ATOM   8761  C C     . ASN C 1 274 ? -23.070  -98.088  -12.847 1.00 22.07  ? 274  ASN C C     1 
ATOM   8762  O O     . ASN C 1 274 ? -22.447  -97.025  -12.699 1.00 21.24  ? 274  ASN C O     1 
ATOM   8763  C CB    . ASN C 1 274 ? -22.320  -99.963  -14.339 1.00 20.24  ? 274  ASN C CB    1 
ATOM   8764  C CG    . ASN C 1 274 ? -22.716  -100.894 -15.468 1.00 24.64  ? 274  ASN C CG    1 
ATOM   8765  O OD1   . ASN C 1 274 ? -23.439  -100.494 -16.400 1.00 24.13  ? 274  ASN C OD1   1 
ATOM   8766  N ND2   . ASN C 1 274 ? -22.228  -102.138 -15.413 1.00 19.99  ? 274  ASN C ND2   1 
ATOM   8767  N N     . ILE C 1 275 ? -23.579  -98.781  -11.819 1.00 21.40  ? 275  ILE C N     1 
ATOM   8768  C CA    . ILE C 1 275 ? -23.463  -98.304  -10.454 1.00 21.70  ? 275  ILE C CA    1 
ATOM   8769  C C     . ILE C 1 275 ? -23.032  -99.498  -9.596  1.00 23.34  ? 275  ILE C C     1 
ATOM   8770  O O     . ILE C 1 275 ? -23.610  -100.599 -9.705  1.00 23.36  ? 275  ILE C O     1 
ATOM   8771  C CB    . ILE C 1 275 ? -24.797  -97.696  -9.955  1.00 20.58  ? 275  ILE C CB    1 
ATOM   8772  C CG1   . ILE C 1 275 ? -24.801  -97.430  -8.456  1.00 22.02  ? 275  ILE C CG1   1 
ATOM   8773  C CG2   . ILE C 1 275 ? -25.961  -98.624  -10.259 1.00 18.22  ? 275  ILE C CG2   1 
ATOM   8774  C CD1   . ILE C 1 275 ? -24.293  -96.066  -8.070  1.00 24.30  ? 275  ILE C CD1   1 
ATOM   8775  N N     . LEU C 1 276 ? -22.038  -99.251  -8.725  1.00 20.07  ? 276  LEU C N     1 
ATOM   8776  C CA    . LEU C 1 276 ? -21.677  -100.194 -7.669  1.00 23.68  ? 276  LEU C CA    1 
ATOM   8777  C C     . LEU C 1 276 ? -22.209  -99.658  -6.338  1.00 23.29  ? 276  LEU C C     1 
ATOM   8778  O O     . LEU C 1 276 ? -21.984  -98.484  -6.003  1.00 25.73  ? 276  LEU C O     1 
ATOM   8779  C CB    . LEU C 1 276 ? -20.153  -100.331 -7.581  1.00 22.98  ? 276  LEU C CB    1 
ATOM   8780  C CG    . LEU C 1 276 ? -19.431  -100.979 -8.770  1.00 22.32  ? 276  LEU C CG    1 
ATOM   8781  C CD1   . LEU C 1 276 ? -17.937  -101.078 -8.448  1.00 19.55  ? 276  LEU C CD1   1 
ATOM   8782  C CD2   . LEU C 1 276 ? -20.019  -102.369 -8.985  1.00 23.17  ? 276  LEU C CD2   1 
ATOM   8783  N N     . VAL C 1 277 ? -22.873  -100.527 -5.570  1.00 23.78  ? 277  VAL C N     1 
ATOM   8784  C CA    . VAL C 1 277 ? -23.259  -100.198 -4.205  1.00 23.83  ? 277  VAL C CA    1 
ATOM   8785  C C     . VAL C 1 277 ? -22.337  -101.001 -3.298  1.00 24.52  ? 277  VAL C C     1 
ATOM   8786  O O     . VAL C 1 277 ? -22.266  -102.227 -3.416  1.00 22.94  ? 277  VAL C O     1 
ATOM   8787  C CB    . VAL C 1 277 ? -24.747  -100.516 -3.935  1.00 24.14  ? 277  VAL C CB    1 
ATOM   8788  C CG1   . VAL C 1 277 ? -25.139  -100.269 -2.479  1.00 21.51  ? 277  VAL C CG1   1 
ATOM   8789  C CG2   . VAL C 1 277 ? -25.651  -99.714  -4.871  1.00 19.85  ? 277  VAL C CG2   1 
ATOM   8790  N N     . ASN C 1 278 ? -21.642  -100.296 -2.395  1.00 23.76  ? 278  ASN C N     1 
ATOM   8791  C CA    . ASN C 1 278 ? -20.585  -100.893 -1.614  1.00 22.43  ? 278  ASN C CA    1 
ATOM   8792  C C     . ASN C 1 278 ? -21.081  -101.365 -0.255  1.00 24.43  ? 278  ASN C C     1 
ATOM   8793  O O     . ASN C 1 278 ? -21.816  -100.644 0.415   1.00 23.91  ? 278  ASN C O     1 
ATOM   8794  C CB    . ASN C 1 278 ? -19.479  -99.884  -1.329  1.00 24.40  ? 278  ASN C CB    1 
ATOM   8795  C CG    . ASN C 1 278 ? -18.402  -100.528 -0.491  1.00 26.50  ? 278  ASN C CG    1 
ATOM   8796  O OD1   . ASN C 1 278 ? -17.749  -101.474 -0.966  1.00 25.59  ? 278  ASN C OD1   1 
ATOM   8797  N ND2   . ASN C 1 278 ? -18.260  -100.087 0.754   1.00 23.38  ? 278  ASN C ND2   1 
ATOM   8798  N N     . ILE C 1 279 ? -20.612  -102.550 0.169   1.00 23.78  ? 279  ILE C N     1 
ATOM   8799  C CA    . ILE C 1 279 ? -20.756  -102.967 1.556   1.00 25.80  ? 279  ILE C CA    1 
ATOM   8800  C C     . ILE C 1 279 ? -19.375  -103.358 2.104   1.00 26.75  ? 279  ILE C C     1 
ATOM   8801  O O     . ILE C 1 279 ? -18.531  -103.930 1.385   1.00 25.83  ? 279  ILE C O     1 
ATOM   8802  C CB    . ILE C 1 279 ? -21.784  -104.106 1.714   1.00 27.72  ? 279  ILE C CB    1 
ATOM   8803  C CG1   . ILE C 1 279 ? -21.284  -105.345 1.074   1.00 31.93  ? 279  ILE C CG1   1 
ATOM   8804  C CG2   . ILE C 1 279 ? -23.156  -103.750 1.125   1.00 26.09  ? 279  ILE C CG2   1 
ATOM   8805  C CD1   . ILE C 1 279 ? -22.237  -106.515 1.323   1.00 41.92  ? 279  ILE C CD1   1 
ATOM   8806  N N     . GLY C 1 280 ? -19.137  -103.062 3.394   1.00 21.57  ? 280  GLY C N     1 
ATOM   8807  C CA    . GLY C 1 280 ? -17.911  -103.499 4.055   1.00 19.62  ? 280  GLY C CA    1 
ATOM   8808  C C     . GLY C 1 280 ? -18.197  -104.684 4.969   1.00 21.04  ? 280  GLY C C     1 
ATOM   8809  O O     . GLY C 1 280 ? -19.044  -104.549 5.847   1.00 20.84  ? 280  GLY C O     1 
ATOM   8810  N N     . LEU C 1 281 ? -17.510  -105.829 4.780   1.00 22.15  ? 281  LEU C N     1 
ATOM   8811  C CA    . LEU C 1 281 ? -17.760  -106.999 5.622   1.00 20.76  ? 281  LEU C CA    1 
ATOM   8812  C C     . LEU C 1 281 ? -17.149  -106.781 7.005   1.00 21.38  ? 281  LEU C C     1 
ATOM   8813  O O     . LEU C 1 281 ? -16.237  -105.947 7.173   1.00 22.54  ? 281  LEU C O     1 
ATOM   8814  C CB    . LEU C 1 281 ? -17.214  -108.271 4.970   1.00 19.90  ? 281  LEU C CB    1 
ATOM   8815  C CG    . LEU C 1 281 ? -17.686  -108.552 3.536   1.00 21.00  ? 281  LEU C CG    1 
ATOM   8816  C CD1   . LEU C 1 281 ? -17.167  -109.911 3.019   1.00 20.70  ? 281  LEU C CD1   1 
ATOM   8817  C CD2   . LEU C 1 281 ? -19.240  -108.477 3.396   1.00 18.09  ? 281  LEU C CD2   1 
ATOM   8818  N N     . THR C 1 282 ? -17.655  -107.539 8.000   1.00 20.64  ? 282  THR C N     1 
ATOM   8819  C CA    . THR C 1 282 ? -17.045  -107.617 9.326   1.00 22.29  ? 282  THR C CA    1 
ATOM   8820  C C     . THR C 1 282 ? -15.668  -108.268 9.228   1.00 22.62  ? 282  THR C C     1 
ATOM   8821  O O     . THR C 1 282 ? -15.321  -108.880 8.205   1.00 21.31  ? 282  THR C O     1 
ATOM   8822  C CB    . THR C 1 282 ? -17.934  -108.382 10.311  1.00 22.40  ? 282  THR C CB    1 
ATOM   8823  O OG1   . THR C 1 282 ? -17.879  -109.751 9.918   1.00 23.42  ? 282  THR C OG1   1 
ATOM   8824  C CG2   . THR C 1 282 ? -19.359  -107.864 10.358  1.00 20.54  ? 282  THR C CG2   1 
ATOM   8825  N N     . GLY C 1 283 ? -14.907  -108.180 10.326  1.00 25.02  ? 283  GLY C N     1 
ATOM   8826  C CA    . GLY C 1 283 ? -13.575  -108.787 10.391  1.00 26.62  ? 283  GLY C CA    1 
ATOM   8827  C C     . GLY C 1 283 ? -13.582  -110.226 9.876   1.00 26.91  ? 283  GLY C C     1 
ATOM   8828  O O     . GLY C 1 283 ? -12.731  -110.610 9.072   1.00 25.09  ? 283  GLY C O     1 
ATOM   8829  N N     . THR C 1 284 ? -14.593  -110.999 10.304  1.00 26.35  ? 284  THR C N     1 
ATOM   8830  C CA    . THR C 1 284 ? -14.658  -112.419 9.985   1.00 27.85  ? 284  THR C CA    1 
ATOM   8831  C C     . THR C 1 284 ? -15.406  -112.674 8.683   1.00 28.31  ? 284  THR C C     1 
ATOM   8832  O O     . THR C 1 284 ? -15.580  -113.836 8.333   1.00 30.24  ? 284  THR C O     1 
ATOM   8833  C CB    . THR C 1 284 ? -15.277  -113.195 11.150  1.00 28.83  ? 284  THR C CB    1 
ATOM   8834  O OG1   . THR C 1 284 ? -16.548  -112.567 11.321  1.00 31.96  ? 284  THR C OG1   1 
ATOM   8835  C CG2   . THR C 1 284 ? -14.424  -113.181 12.407  1.00 25.90  ? 284  THR C CG2   1 
ATOM   8836  N N     . GLY C 1 285 ? -15.821  -111.623 7.954   1.00 25.24  ? 285  GLY C N     1 
ATOM   8837  C CA    . GLY C 1 285 ? -16.357  -111.843 6.613   1.00 23.61  ? 285  GLY C CA    1 
ATOM   8838  C C     . GLY C 1 285 ? -17.887  -111.898 6.508   1.00 29.74  ? 285  GLY C C     1 
ATOM   8839  O O     . GLY C 1 285 ? -18.405  -112.316 5.475   1.00 29.29  ? 285  GLY C O     1 
ATOM   8840  N N     . ALA C 1 286 ? -18.632  -111.461 7.541   1.00 27.26  ? 286  ALA C N     1 
ATOM   8841  C CA    . ALA C 1 286 ? -20.089  -111.419 7.452   1.00 27.08  ? 286  ALA C CA    1 
ATOM   8842  C C     . ALA C 1 286 ? -20.559  -110.103 6.814   1.00 30.98  ? 286  ALA C C     1 
ATOM   8843  O O     . ALA C 1 286 ? -19.904  -109.075 6.931   1.00 29.77  ? 286  ALA C O     1 
ATOM   8844  C CB    . ALA C 1 286 ? -20.712  -111.599 8.835   1.00 22.29  ? 286  ALA C CB    1 
ATOM   8845  N N     . ILE C 1 287 ? -21.727  -110.147 6.162   1.00 32.88  ? 287  ILE C N     1 
ATOM   8846  C CA    . ILE C 1 287 ? -22.451  -108.946 5.782   1.00 28.92  ? 287  ILE C CA    1 
ATOM   8847  C C     . ILE C 1 287 ? -23.053  -108.347 7.053   1.00 28.81  ? 287  ILE C C     1 
ATOM   8848  O O     . ILE C 1 287 ? -23.812  -108.986 7.756   1.00 27.76  ? 287  ILE C O     1 
ATOM   8849  C CB    . ILE C 1 287 ? -23.563  -109.272 4.781   1.00 26.20  ? 287  ILE C CB    1 
ATOM   8850  C CG1   . ILE C 1 287 ? -22.979  -109.972 3.560   1.00 30.05  ? 287  ILE C CG1   1 
ATOM   8851  C CG2   . ILE C 1 287 ? -24.310  -107.990 4.400   1.00 25.79  ? 287  ILE C CG2   1 
ATOM   8852  C CD1   . ILE C 1 287 ? -23.959  -110.137 2.404   1.00 33.13  ? 287  ILE C CD1   1 
ATOM   8853  N N     . PRO C 1 288 ? -22.726  -107.098 7.423   1.00 25.74  ? 288  PRO C N     1 
ATOM   8854  C CA    . PRO C 1 288 ? -23.344  -106.509 8.607   1.00 24.76  ? 288  PRO C CA    1 
ATOM   8855  C C     . PRO C 1 288 ? -24.842  -106.275 8.440   1.00 28.38  ? 288  PRO C C     1 
ATOM   8856  O O     . PRO C 1 288 ? -25.319  -106.033 7.331   1.00 32.16  ? 288  PRO C O     1 
ATOM   8857  C CB    . PRO C 1 288 ? -22.584  -105.204 8.841   1.00 22.73  ? 288  PRO C CB    1 
ATOM   8858  C CG    . PRO C 1 288 ? -21.729  -105.024 7.601   1.00 23.44  ? 288  PRO C CG    1 
ATOM   8859  C CD    . PRO C 1 288 ? -21.811  -106.212 6.691   1.00 20.94  ? 288  PRO C CD    1 
ATOM   8860  N N     . ALA C 1 289 ? -25.573  -106.288 9.563   1.00 30.32  ? 289  ALA C N     1 
ATOM   8861  C CA    . ALA C 1 289 ? -27.021  -106.125 9.574   1.00 26.15  ? 289  ALA C CA    1 
ATOM   8862  C C     . ALA C 1 289 ? -27.435  -104.816 8.884   1.00 25.99  ? 289  ALA C C     1 
ATOM   8863  O O     . ALA C 1 289 ? -28.410  -104.811 8.122   1.00 25.19  ? 289  ALA C O     1 
ATOM   8864  C CB    . ALA C 1 289 ? -27.558  -106.255 11.006  1.00 20.81  ? 289  ALA C CB    1 
ATOM   8865  N N     . ALA C 1 290 ? -26.705  -103.715 9.108   1.00 23.90  ? 290  ALA C N     1 
ATOM   8866  C CA    . ALA C 1 290 ? -27.083  -102.446 8.484   1.00 23.08  ? 290  ALA C CA    1 
ATOM   8867  C C     . ALA C 1 290 ? -27.088  -102.570 6.962   1.00 24.43  ? 290  ALA C C     1 
ATOM   8868  O O     . ALA C 1 290 ? -28.013  -102.075 6.293   1.00 22.83  ? 290  ALA C O     1 
ATOM   8869  C CB    . ALA C 1 290 ? -26.244  -101.263 8.962   1.00 18.75  ? 290  ALA C CB    1 
ATOM   8870  N N     . ALA C 1 291 ? -26.068  -103.245 6.416   1.00 23.98  ? 291  ALA C N     1 
ATOM   8871  C CA    . ALA C 1 291 ? -25.973  -103.376 4.967   1.00 25.25  ? 291  ALA C CA    1 
ATOM   8872  C C     . ALA C 1 291 ? -27.142  -104.215 4.450   1.00 27.09  ? 291  ALA C C     1 
ATOM   8873  O O     . ALA C 1 291 ? -27.662  -103.934 3.376   1.00 28.81  ? 291  ALA C O     1 
ATOM   8874  C CB    . ALA C 1 291 ? -24.636  -103.995 4.576   1.00 23.08  ? 291  ALA C CB    1 
ATOM   8875  N N     . GLN C 1 292 ? -27.534  -105.256 5.197   1.00 26.50  ? 292  GLN C N     1 
ATOM   8876  C CA    . GLN C 1 292 ? -28.660  -106.098 4.822   1.00 28.08  ? 292  GLN C CA    1 
ATOM   8877  C C     . GLN C 1 292 ? -29.938  -105.259 4.685   1.00 27.47  ? 292  GLN C C     1 
ATOM   8878  O O     . GLN C 1 292 ? -30.691  -105.453 3.729   1.00 27.03  ? 292  GLN C O     1 
ATOM   8879  C CB    . GLN C 1 292 ? -28.865  -107.301 5.745   1.00 29.61  ? 292  GLN C CB    1 
ATOM   8880  C CG    . GLN C 1 292 ? -27.991  -108.510 5.407   1.00 48.71  ? 292  GLN C CG    1 
ATOM   8881  C CD    . GLN C 1 292 ? -27.931  -109.515 6.551   1.00 71.00  ? 292  GLN C CD    1 
ATOM   8882  O OE1   . GLN C 1 292 ? -26.860  -109.865 7.092   1.00 57.80  ? 292  GLN C OE1   1 
ATOM   8883  N NE2   . GLN C 1 292 ? -29.109  -109.970 6.967   1.00 78.96  ? 292  GLN C NE2   1 
ATOM   8884  N N     . THR C 1 293 ? -30.162  -104.299 5.603   1.00 23.55  ? 293  THR C N     1 
ATOM   8885  C CA    . THR C 1 293 ? -31.340  -103.443 5.523   1.00 21.01  ? 293  THR C CA    1 
ATOM   8886  C C     . THR C 1 293 ? -31.345  -102.681 4.186   1.00 22.23  ? 293  THR C C     1 
ATOM   8887  O O     . THR C 1 293 ? -32.348  -102.683 3.480   1.00 23.02  ? 293  THR C O     1 
ATOM   8888  C CB    . THR C 1 293 ? -31.380  -102.489 6.724   1.00 23.27  ? 293  THR C CB    1 
ATOM   8889  O OG1   . THR C 1 293 ? -31.689  -103.286 7.870   1.00 26.01  ? 293  THR C OG1   1 
ATOM   8890  C CG2   . THR C 1 293 ? -32.326  -101.310 6.535   1.00 17.39  ? 293  THR C CG2   1 
ATOM   8891  N N     . TYR C 1 294 ? -30.215  -102.055 3.825   1.00 19.62  ? 294  TYR C N     1 
ATOM   8892  C CA    . TYR C 1 294 ? -30.110  -101.292 2.589   1.00 23.53  ? 294  TYR C CA    1 
ATOM   8893  C C     . TYR C 1 294 ? -30.302  -102.201 1.372   1.00 23.96  ? 294  TYR C C     1 
ATOM   8894  O O     . TYR C 1 294 ? -30.965  -101.824 0.402   1.00 24.25  ? 294  TYR C O     1 
ATOM   8895  C CB    . TYR C 1 294 ? -28.797  -100.500 2.505   1.00 21.35  ? 294  TYR C CB    1 
ATOM   8896  C CG    . TYR C 1 294 ? -28.867  -99.224  3.321   1.00 22.97  ? 294  TYR C CG    1 
ATOM   8897  C CD1   . TYR C 1 294 ? -28.823  -99.265  4.715   1.00 23.49  ? 294  TYR C CD1   1 
ATOM   8898  C CD2   . TYR C 1 294 ? -28.994  -97.982  2.696   1.00 21.17  ? 294  TYR C CD2   1 
ATOM   8899  C CE1   . TYR C 1 294 ? -28.847  -98.096  5.457   1.00 24.48  ? 294  TYR C CE1   1 
ATOM   8900  C CE2   . TYR C 1 294 ? -29.040  -96.807  3.438   1.00 21.53  ? 294  TYR C CE2   1 
ATOM   8901  C CZ    . TYR C 1 294 ? -28.968  -96.867  4.820   1.00 22.96  ? 294  TYR C CZ    1 
ATOM   8902  O OH    . TYR C 1 294 ? -29.055  -95.726  5.572   1.00 23.40  ? 294  TYR C OH    1 
ATOM   8903  N N     . MET C 1 295 ? -29.754  -103.418 1.444   1.00 22.67  ? 295  MET C N     1 
ATOM   8904  C CA    . MET C 1 295 ? -29.926  -104.350 0.333   1.00 27.82  ? 295  MET C CA    1 
ATOM   8905  C C     . MET C 1 295 ? -31.373  -104.783 0.128   1.00 24.80  ? 295  MET C C     1 
ATOM   8906  O O     . MET C 1 295 ? -31.818  -104.850 -1.017  1.00 23.66  ? 295  MET C O     1 
ATOM   8907  C CB    . MET C 1 295 ? -28.949  -105.513 0.450   1.00 30.11  ? 295  MET C CB    1 
ATOM   8908  C CG    . MET C 1 295 ? -27.524  -105.013 0.068   1.00 32.16  ? 295  MET C CG    1 
ATOM   8909  S SD    . MET C 1 295 ? -26.388  -106.396 0.276   1.00 50.94  ? 295  MET C SD    1 
ATOM   8910  C CE    . MET C 1 295 ? -26.530  -106.905 1.997   1.00 48.79  ? 295  MET C CE    1 
ATOM   8911  N N     . HIS C 1 296 ? -32.103  -105.040 1.222   1.00 23.62  ? 296  HIS C N     1 
ATOM   8912  C CA    . HIS C 1 296 ? -33.513  -105.402 1.119   1.00 24.71  ? 296  HIS C CA    1 
ATOM   8913  C C     . HIS C 1 296 ? -34.318  -104.274 0.469   1.00 26.17  ? 296  HIS C C     1 
ATOM   8914  O O     . HIS C 1 296 ? -35.130  -104.537 -0.429  1.00 29.29  ? 296  HIS C O     1 
ATOM   8915  C CB    . HIS C 1 296 ? -34.089  -105.894 2.449   1.00 26.66  ? 296  HIS C CB    1 
ATOM   8916  C CG    . HIS C 1 296 ? -33.649  -107.278 2.784   1.00 45.31  ? 296  HIS C CG    1 
ATOM   8917  N ND1   . HIS C 1 296 ? -33.062  -107.600 3.990   1.00 53.87  ? 296  HIS C ND1   1 
ATOM   8918  C CD2   . HIS C 1 296 ? -33.623  -108.418 2.059   1.00 53.19  ? 296  HIS C CD2   1 
ATOM   8919  C CE1   . HIS C 1 296 ? -32.734  -108.889 4.011   1.00 43.87  ? 296  HIS C CE1   1 
ATOM   8920  N NE2   . HIS C 1 296 ? -33.059  -109.393 2.852   1.00 45.96  ? 296  HIS C NE2   1 
ATOM   8921  N N     . LEU C 1 297 ? -34.080  -103.025 0.891   1.00 23.06  ? 297  LEU C N     1 
ATOM   8922  C CA    . LEU C 1 297 ? -34.806  -101.896 0.329   1.00 22.94  ? 297  LEU C CA    1 
ATOM   8923  C C     . LEU C 1 297 ? -34.453  -101.732 -1.150  1.00 23.81  ? 297  LEU C C     1 
ATOM   8924  O O     . LEU C 1 297 ? -35.348  -101.617 -1.987  1.00 22.81  ? 297  LEU C O     1 
ATOM   8925  C CB    . LEU C 1 297 ? -34.614  -100.606 1.127   1.00 19.85  ? 297  LEU C CB    1 
ATOM   8926  C CG    . LEU C 1 297 ? -35.099  -100.681 2.580   1.00 21.22  ? 297  LEU C CG    1 
ATOM   8927  C CD1   . LEU C 1 297 ? -34.556  -99.495  3.385   1.00 20.11  ? 297  LEU C CD1   1 
ATOM   8928  C CD2   . LEU C 1 297 ? -36.642  -100.793 2.663   1.00 19.90  ? 297  LEU C CD2   1 
ATOM   8929  N N     . LEU C 1 298 ? -33.154  -101.763 -1.480  1.00 22.21  ? 298  LEU C N     1 
ATOM   8930  C CA    . LEU C 1 298 ? -32.772  -101.580 -2.874  1.00 22.97  ? 298  LEU C CA    1 
ATOM   8931  C C     . LEU C 1 298 ? -33.386  -102.706 -3.721  1.00 26.04  ? 298  LEU C C     1 
ATOM   8932  O O     . LEU C 1 298 ? -33.820  -102.471 -4.857  1.00 24.60  ? 298  LEU C O     1 
ATOM   8933  C CB    . LEU C 1 298 ? -31.251  -101.590 -2.967  1.00 21.73  ? 298  LEU C CB    1 
ATOM   8934  C CG    . LEU C 1 298 ? -30.683  -101.480 -4.389  1.00 21.84  ? 298  LEU C CG    1 
ATOM   8935  C CD1   . LEU C 1 298 ? -31.204  -100.230 -5.058  1.00 23.40  ? 298  LEU C CD1   1 
ATOM   8936  C CD2   . LEU C 1 298 ? -29.198  -101.441 -4.402  1.00 20.93  ? 298  LEU C CD2   1 
ATOM   8937  N N     . GLY C 1 299 ? -33.412  -103.933 -3.155  1.00 22.34  ? 299  GLY C N     1 
ATOM   8938  C CA    . GLY C 1 299 ? -33.919  -105.110 -3.854  1.00 23.61  ? 299  GLY C CA    1 
ATOM   8939  C C     . GLY C 1 299 ? -35.395  -104.946 -4.241  1.00 22.07  ? 299  GLY C C     1 
ATOM   8940  O O     . GLY C 1 299 ? -35.805  -105.374 -5.320  1.00 22.68  ? 299  GLY C O     1 
ATOM   8941  N N     . ARG C 1 300 ? -36.190  -104.296 -3.383  1.00 21.29  ? 300  ARG C N     1 
ATOM   8942  C CA    . ARG C 1 300 ? -37.587  -104.084 -3.727  1.00 22.37  ? 300  ARG C CA    1 
ATOM   8943  C C     . ARG C 1 300 ? -37.660  -103.129 -4.912  1.00 23.27  ? 300  ARG C C     1 
ATOM   8944  O O     . ARG C 1 300 ? -38.469  -103.340 -5.807  1.00 23.23  ? 300  ARG C O     1 
ATOM   8945  C CB    . ARG C 1 300 ? -38.396  -103.524 -2.559  1.00 24.54  ? 300  ARG C CB    1 
ATOM   8946  C CG    . ARG C 1 300 ? -38.678  -104.571 -1.497  1.00 28.56  ? 300  ARG C CG    1 
ATOM   8947  C CD    . ARG C 1 300 ? -39.138  -103.774 -0.297  1.00 33.10  ? 300  ARG C CD    1 
ATOM   8948  N NE    . ARG C 1 300 ? -39.460  -104.683 0.802   1.00 38.42  ? 300  ARG C NE    1 
ATOM   8949  C CZ    . ARG C 1 300 ? -40.517  -105.481 0.848   1.00 39.12  ? 300  ARG C CZ    1 
ATOM   8950  N NH1   . ARG C 1 300 ? -41.494  -105.409 -0.052  1.00 27.93  ? 300  ARG C NH1   1 
ATOM   8951  N NH2   . ARG C 1 300 ? -40.601  -106.280 1.892   1.00 38.91  ? 300  ARG C NH2   1 
ATOM   8952  N N     . TRP C 1 301 ? -36.788  -102.105 -4.932  1.00 19.60  ? 301  TRP C N     1 
ATOM   8953  C CA    . TRP C 1 301 ? -36.830  -101.162 -6.038  1.00 19.97  ? 301  TRP C CA    1 
ATOM   8954  C C     . TRP C 1 301 ? -36.357  -101.820 -7.342  1.00 21.97  ? 301  TRP C C     1 
ATOM   8955  O O     . TRP C 1 301 ? -36.982  -101.616 -8.386  1.00 23.04  ? 301  TRP C O     1 
ATOM   8956  C CB    . TRP C 1 301 ? -36.024  -99.894  -5.720  1.00 17.52  ? 301  TRP C CB    1 
ATOM   8957  C CG    . TRP C 1 301 ? -36.211  -98.831  -6.768  1.00 18.70  ? 301  TRP C CG    1 
ATOM   8958  C CD1   . TRP C 1 301 ? -37.230  -97.911  -6.818  1.00 18.40  ? 301  TRP C CD1   1 
ATOM   8959  C CD2   . TRP C 1 301 ? -35.394  -98.603  -7.945  1.00 18.24  ? 301  TRP C CD2   1 
ATOM   8960  N NE1   . TRP C 1 301 ? -37.089  -97.121  -7.930  1.00 19.28  ? 301  TRP C NE1   1 
ATOM   8961  C CE2   . TRP C 1 301 ? -35.979  -97.521  -8.643  1.00 16.97  ? 301  TRP C CE2   1 
ATOM   8962  C CE3   . TRP C 1 301 ? -34.234  -99.205  -8.469  1.00 17.50  ? 301  TRP C CE3   1 
ATOM   8963  C CZ2   . TRP C 1 301 ? -35.452  -97.026  -9.836  1.00 16.30  ? 301  TRP C CZ2   1 
ATOM   8964  C CZ3   . TRP C 1 301 ? -33.727  -98.722  -9.661  1.00 18.08  ? 301  TRP C CZ3   1 
ATOM   8965  C CH2   . TRP C 1 301 ? -34.325  -97.642  -10.338 1.00 17.01  ? 301  TRP C CH2   1 
ATOM   8966  N N     . THR C 1 302 ? -35.253  -102.586 -7.293  1.00 20.95  ? 302  THR C N     1 
ATOM   8967  C CA    . THR C 1 302 ? -34.691  -103.090 -8.543  1.00 22.91  ? 302  THR C CA    1 
ATOM   8968  C C     . THR C 1 302 ? -35.614  -104.163 -9.119  1.00 23.94  ? 302  THR C C     1 
ATOM   8969  O O     . THR C 1 302 ? -35.701  -104.293 -10.329 1.00 31.35  ? 302  THR C O     1 
ATOM   8970  C CB    . THR C 1 302 ? -33.247  -103.587 -8.401  1.00 20.68  ? 302  THR C CB    1 
ATOM   8971  O OG1   . THR C 1 302 ? -33.359  -104.689 -7.495  1.00 20.04  ? 302  THR C OG1   1 
ATOM   8972  C CG2   . THR C 1 302 ? -32.282  -102.512 -7.929  1.00 16.83  ? 302  THR C CG2   1 
ATOM   8973  N N     . ALA C 1 303 ? -36.313  -104.929 -8.269  1.00 22.52  ? 303  ALA C N     1 
ATOM   8974  C CA    . ALA C 1 303 ? -37.279  -105.893 -8.786  1.00 20.64  ? 303  ALA C CA    1 
ATOM   8975  C C     . ALA C 1 303 ? -38.381  -105.162 -9.582  1.00 27.68  ? 303  ALA C C     1 
ATOM   8976  O O     . ALA C 1 303 ? -38.754  -105.577 -10.675 1.00 25.46  ? 303  ALA C O     1 
ATOM   8977  C CB    . ALA C 1 303 ? -37.875  -106.763 -7.674  1.00 15.40  ? 303  ALA C CB    1 
ATOM   8978  N N     . MET C 1 304 ? -38.881  -104.039 -9.053  1.00 27.39  ? 304  MET C N     1 
ATOM   8979  C CA    . MET C 1 304 ? -39.890  -103.260 -9.742  1.00 23.88  ? 304  MET C CA    1 
ATOM   8980  C C     . MET C 1 304 ? -39.304  -102.698 -11.046 1.00 25.51  ? 304  MET C C     1 
ATOM   8981  O O     . MET C 1 304 ? -39.994  -102.688 -12.075 1.00 23.85  ? 304  MET C O     1 
ATOM   8982  C CB    . MET C 1 304 ? -40.447  -102.191 -8.794  1.00 21.46  ? 304  MET C CB    1 
ATOM   8983  C CG    . MET C 1 304 ? -41.388  -101.174 -9.413  1.00 22.66  ? 304  MET C CG    1 
ATOM   8984  S SD    . MET C 1 304 ? -40.585  -99.890  -10.397 1.00 24.52  ? 304  MET C SD    1 
ATOM   8985  C CE    . MET C 1 304 ? -39.671  -98.925  -9.169  1.00 25.89  ? 304  MET C CE    1 
ATOM   8986  N N     . ALA C 1 305 ? -38.032  -102.260 -11.020 1.00 21.94  ? 305  ALA C N     1 
ATOM   8987  C CA    . ALA C 1 305 ? -37.433  -101.541 -12.137 1.00 21.79  ? 305  ALA C CA    1 
ATOM   8988  C C     . ALA C 1 305 ? -36.822  -102.460 -13.195 1.00 22.03  ? 305  ALA C C     1 
ATOM   8989  O O     . ALA C 1 305 ? -36.304  -101.941 -14.197 1.00 21.93  ? 305  ALA C O     1 
ATOM   8990  C CB    . ALA C 1 305 ? -36.371  -100.575 -11.648 1.00 18.49  ? 305  ALA C CB    1 
ATOM   8991  N N     . ALA C 1 306 ? -36.871  -103.790 -12.974 1.00 20.74  ? 306  ALA C N     1 
ATOM   8992  C CA    . ALA C 1 306 ? -36.244  -104.793 -13.843 1.00 25.01  ? 306  ALA C CA    1 
ATOM   8993  C C     . ALA C 1 306 ? -36.475  -104.559 -15.346 1.00 25.38  ? 306  ALA C C     1 
ATOM   8994  O O     . ALA C 1 306 ? -35.556  -104.773 -16.143 1.00 26.90  ? 306  ALA C O     1 
ATOM   8995  C CB    . ALA C 1 306 ? -36.654  -106.210 -13.437 1.00 21.34  ? 306  ALA C CB    1 
ATOM   8996  N N     . PRO C 1 307 ? -37.677  -104.154 -15.832 1.00 24.75  ? 307  PRO C N     1 
ATOM   8997  C CA    . PRO C 1 307 ? -37.854  -103.975 -17.274 1.00 22.36  ? 307  PRO C CA    1 
ATOM   8998  C C     . PRO C 1 307 ? -36.935  -102.923 -17.877 1.00 25.30  ? 307  PRO C C     1 
ATOM   8999  O O     . PRO C 1 307 ? -36.731  -102.946 -19.074 1.00 32.08  ? 307  PRO C O     1 
ATOM   9000  C CB    . PRO C 1 307 ? -39.337  -103.658 -17.484 1.00 19.55  ? 307  PRO C CB    1 
ATOM   9001  C CG    . PRO C 1 307 ? -39.986  -104.199 -16.212 1.00 22.55  ? 307  PRO C CG    1 
ATOM   9002  C CD    . PRO C 1 307 ? -38.940  -104.015 -15.085 1.00 24.62  ? 307  PRO C CD    1 
ATOM   9003  N N     . VAL C 1 308 ? -36.374  -102.006 -17.076 1.00 23.83  ? 308  VAL C N     1 
ATOM   9004  C CA    . VAL C 1 308 ? -35.596  -100.916 -17.667 1.00 23.34  ? 308  VAL C CA    1 
ATOM   9005  C C     . VAL C 1 308 ? -34.173  -100.845 -17.083 1.00 25.52  ? 308  VAL C C     1 
ATOM   9006  O O     . VAL C 1 308 ? -33.278  -100.280 -17.713 1.00 26.07  ? 308  VAL C O     1 
ATOM   9007  C CB    . VAL C 1 308 ? -36.315  -99.554  -17.557 1.00 19.91  ? 308  VAL C CB    1 
ATOM   9008  C CG1   . VAL C 1 308 ? -36.455  -99.081  -16.112 1.00 16.16  ? 308  VAL C CG1   1 
ATOM   9009  C CG2   . VAL C 1 308 ? -35.601  -98.505  -18.374 1.00 19.41  ? 308  VAL C CG2   1 
ATOM   9010  N N     . LEU C 1 309 ? -33.958  -101.396 -15.877 1.00 23.58  ? 309  LEU C N     1 
ATOM   9011  C CA    . LEU C 1 309 ? -32.697  -101.189 -15.184 1.00 23.42  ? 309  LEU C CA    1 
ATOM   9012  C C     . LEU C 1 309 ? -31.507  -101.684 -16.015 1.00 26.18  ? 309  LEU C C     1 
ATOM   9013  O O     . LEU C 1 309 ? -30.446  -101.058 -15.974 1.00 31.76  ? 309  LEU C O     1 
ATOM   9014  C CB    . LEU C 1 309 ? -32.746  -101.901 -13.832 1.00 22.34  ? 309  LEU C CB    1 
ATOM   9015  C CG    . LEU C 1 309 ? -31.483  -101.783 -12.977 1.00 24.14  ? 309  LEU C CG    1 
ATOM   9016  C CD1   . LEU C 1 309 ? -31.146  -100.323 -12.633 1.00 23.68  ? 309  LEU C CD1   1 
ATOM   9017  C CD2   . LEU C 1 309 ? -31.655  -102.618 -11.715 1.00 23.56  ? 309  LEU C CD2   1 
ATOM   9018  N N     . TYR C 1 310 ? -31.653  -102.831 -16.716 1.00 24.14  ? 310  TYR C N     1 
ATOM   9019  C CA    . TYR C 1 310 ? -30.548  -103.465 -17.437 1.00 23.20  ? 310  TYR C CA    1 
ATOM   9020  C C     . TYR C 1 310 ? -30.381  -102.905 -18.857 1.00 25.97  ? 310  TYR C C     1 
ATOM   9021  O O     . TYR C 1 310 ? -29.280  -102.503 -19.238 1.00 21.84  ? 310  TYR C O     1 
ATOM   9022  C CB    . TYR C 1 310 ? -30.681  -104.989 -17.378 1.00 21.66  ? 310  TYR C CB    1 
ATOM   9023  C CG    . TYR C 1 310 ? -30.835  -105.405 -15.925 1.00 20.58  ? 310  TYR C CG    1 
ATOM   9024  C CD1   . TYR C 1 310 ? -29.779  -105.257 -15.021 1.00 19.17  ? 310  TYR C CD1   1 
ATOM   9025  C CD2   . TYR C 1 310 ? -32.067  -105.848 -15.436 1.00 21.06  ? 310  TYR C CD2   1 
ATOM   9026  C CE1   . TYR C 1 310 ? -29.940  -105.568 -13.680 1.00 19.50  ? 310  TYR C CE1   1 
ATOM   9027  C CE2   . TYR C 1 310 ? -32.244  -106.195 -14.098 1.00 21.33  ? 310  TYR C CE2   1 
ATOM   9028  C CZ    . TYR C 1 310 ? -31.171  -106.046 -13.222 1.00 24.68  ? 310  TYR C CZ    1 
ATOM   9029  O OH    . TYR C 1 310 ? -31.337  -106.361 -11.899 1.00 25.30  ? 310  TYR C OH    1 
ATOM   9030  N N     . LYS C 1 311 ? -31.478  -102.846 -19.629 1.00 26.50  ? 311  LYS C N     1 
ATOM   9031  C CA    . LYS C 1 311 ? -31.386  -102.492 -21.041 1.00 27.46  ? 311  LYS C CA    1 
ATOM   9032  C C     . LYS C 1 311 ? -31.602  -101.005 -21.296 1.00 25.54  ? 311  LYS C C     1 
ATOM   9033  O O     . LYS C 1 311 ? -31.337  -100.548 -22.399 1.00 29.51  ? 311  LYS C O     1 
ATOM   9034  C CB    . LYS C 1 311 ? -32.462  -103.268 -21.819 1.00 30.76  ? 311  LYS C CB    1 
ATOM   9035  C CG    . LYS C 1 311 ? -32.298  -104.787 -21.748 1.00 33.31  ? 311  LYS C CG    1 
ATOM   9036  C CD    . LYS C 1 311 ? -31.097  -105.165 -22.601 1.00 38.25  ? 311  LYS C CD    1 
ATOM   9037  C CE    . LYS C 1 311 ? -30.963  -106.620 -22.929 1.00 48.32  ? 311  LYS C CE    1 
ATOM   9038  N NZ    . LYS C 1 311 ? -29.850  -106.689 -23.896 1.00 49.28  ? 311  LYS C NZ    1 
ATOM   9039  N N     . GLY C 1 312 ? -32.133  -100.245 -20.319 1.00 23.26  ? 312  GLY C N     1 
ATOM   9040  C CA    . GLY C 1 312 ? -32.453  -98.845  -20.550 1.00 18.49  ? 312  GLY C CA    1 
ATOM   9041  C C     . GLY C 1 312 ? -31.192  -98.012  -20.808 1.00 23.85  ? 312  GLY C C     1 
ATOM   9042  O O     . GLY C 1 312 ? -30.151  -98.204  -20.158 1.00 24.35  ? 312  GLY C O     1 
ATOM   9043  N N     . ARG C 1 313 ? -31.293  -97.068  -21.755 1.00 22.01  ? 313  ARG C N     1 
ATOM   9044  C CA    . ARG C 1 313 ? -30.161  -96.242  -22.132 1.00 22.48  ? 313  ARG C CA    1 
ATOM   9045  C C     . ARG C 1 313 ? -30.615  -94.787  -22.203 1.00 24.46  ? 313  ARG C C     1 
ATOM   9046  O O     . ARG C 1 313 ? -31.789  -94.507  -22.472 1.00 23.96  ? 313  ARG C O     1 
ATOM   9047  C CB    . ARG C 1 313 ? -29.598  -96.645  -23.505 1.00 21.10  ? 313  ARG C CB    1 
ATOM   9048  C CG    . ARG C 1 313 ? -28.968  -98.033  -23.531 1.00 22.03  ? 313  ARG C CG    1 
ATOM   9049  C CD    . ARG C 1 313 ? -27.704  -98.098  -22.674 1.00 24.86  ? 313  ARG C CD    1 
ATOM   9050  N NE    . ARG C 1 313 ? -27.081  -99.435  -22.698 1.00 25.39  ? 313  ARG C NE    1 
ATOM   9051  C CZ    . ARG C 1 313 ? -27.429  -100.488 -21.961 1.00 26.24  ? 313  ARG C CZ    1 
ATOM   9052  N NH1   . ARG C 1 313 ? -28.323  -100.399 -20.984 1.00 26.98  ? 313  ARG C NH1   1 
ATOM   9053  N NH2   . ARG C 1 313 ? -26.843  -101.648 -22.163 1.00 28.22  ? 313  ARG C NH2   1 
ATOM   9054  N N     . PRO C 1 314 ? -29.701  -93.823  -21.967 1.00 22.42  ? 314  PRO C N     1 
ATOM   9055  C CA    . PRO C 1 314 ? -30.061  -92.414  -22.088 1.00 23.46  ? 314  PRO C CA    1 
ATOM   9056  C C     . PRO C 1 314 ? -30.516  -92.100  -23.505 1.00 28.30  ? 314  PRO C C     1 
ATOM   9057  O O     . PRO C 1 314 ? -30.104  -92.771  -24.455 1.00 29.02  ? 314  PRO C O     1 
ATOM   9058  C CB    . PRO C 1 314 ? -28.757  -91.649  -21.846 1.00 21.52  ? 314  PRO C CB    1 
ATOM   9059  C CG    . PRO C 1 314 ? -27.854  -92.667  -21.178 1.00 25.66  ? 314  PRO C CG    1 
ATOM   9060  C CD    . PRO C 1 314 ? -28.290  -94.059  -21.619 1.00 21.13  ? 314  PRO C CD    1 
ATOM   9061  N N     . VAL C 1 315 ? -31.327  -91.060  -23.646 1.00 28.52  ? 315  VAL C N     1 
ATOM   9062  C CA    . VAL C 1 315 ? -31.878  -90.717  -24.940 1.00 30.05  ? 315  VAL C CA    1 
ATOM   9063  C C     . VAL C 1 315 ? -32.095  -89.206  -24.899 1.00 32.90  ? 315  VAL C C     1 
ATOM   9064  O O     . VAL C 1 315 ? -32.277  -88.660  -23.820 1.00 31.42  ? 315  VAL C O     1 
ATOM   9065  C CB    . VAL C 1 315 ? -33.177  -91.558  -25.025 1.00 30.45  ? 315  VAL C CB    1 
ATOM   9066  C CG1   . VAL C 1 315 ? -34.286  -91.101  -24.061 1.00 25.40  ? 315  VAL C CG1   1 
ATOM   9067  C CG2   . VAL C 1 315 ? -33.663  -91.740  -26.449 1.00 29.06  ? 315  VAL C CG2   1 
ATOM   9068  N N     . PRO C 1 316 ? -31.991  -88.456  -26.012 1.00 34.97  ? 316  PRO C N     1 
ATOM   9069  C CA    . PRO C 1 316 ? -32.109  -86.991  -25.934 1.00 38.39  ? 316  PRO C CA    1 
ATOM   9070  C C     . PRO C 1 316 ? -33.569  -86.520  -25.742 1.00 37.29  ? 316  PRO C C     1 
ATOM   9071  O O     . PRO C 1 316 ? -34.216  -85.995  -26.646 1.00 33.61  ? 316  PRO C O     1 
ATOM   9072  C CB    . PRO C 1 316 ? -31.422  -86.520  -27.236 1.00 33.48  ? 316  PRO C CB    1 
ATOM   9073  C CG    . PRO C 1 316 ? -31.806  -87.663  -28.209 1.00 33.95  ? 316  PRO C CG    1 
ATOM   9074  C CD    . PRO C 1 316 ? -31.803  -88.965  -27.389 1.00 34.62  ? 316  PRO C CD    1 
ATOM   9075  N N     . VAL C 1 317 ? -34.129  -86.821  -24.572 1.00 36.02  ? 317  VAL C N     1 
ATOM   9076  C CA    . VAL C 1 317 ? -35.479  -86.421  -24.214 1.00 33.44  ? 317  VAL C CA    1 
ATOM   9077  C C     . VAL C 1 317 ? -35.341  -85.747  -22.867 1.00 34.92  ? 317  VAL C C     1 
ATOM   9078  O O     . VAL C 1 317 ? -34.808  -86.354  -21.948 1.00 38.60  ? 317  VAL C O     1 
ATOM   9079  C CB    . VAL C 1 317 ? -36.474  -87.587  -24.117 1.00 31.19  ? 317  VAL C CB    1 
ATOM   9080  C CG1   . VAL C 1 317 ? -37.841  -87.090  -23.631 1.00 32.67  ? 317  VAL C CG1   1 
ATOM   9081  C CG2   . VAL C 1 317 ? -36.583  -88.365  -25.423 1.00 24.49  ? 317  VAL C CG2   1 
ATOM   9082  N N     . THR C 1 318 ? -35.711  -84.470  -22.787 1.00 32.71  ? 318  THR C N     1 
ATOM   9083  C CA    . THR C 1 318 ? -35.482  -83.763  -21.536 1.00 33.33  ? 318  THR C CA    1 
ATOM   9084  C C     . THR C 1 318 ? -36.811  -83.537  -20.805 1.00 35.30  ? 318  THR C C     1 
ATOM   9085  O O     . THR C 1 318 ? -37.900  -83.676  -21.372 1.00 39.04  ? 318  THR C O     1 
ATOM   9086  C CB    . THR C 1 318 ? -34.718  -82.465  -21.800 1.00 34.02  ? 318  THR C CB    1 
ATOM   9087  O OG1   . THR C 1 318 ? -35.560  -81.652  -22.622 1.00 32.46  ? 318  THR C OG1   1 
ATOM   9088  C CG2   . THR C 1 318 ? -33.346  -82.713  -22.409 1.00 29.74  ? 318  THR C CG2   1 
ATOM   9089  N N     . SER C 1 319 ? -36.705  -83.174  -19.526 1.00 29.72  ? 319  SER C N     1 
ATOM   9090  C CA    . SER C 1 319 ? -37.894  -82.957  -18.737 1.00 27.99  ? 319  SER C CA    1 
ATOM   9091  C C     . SER C 1 319 ? -38.182  -81.464  -18.666 1.00 25.72  ? 319  SER C C     1 
ATOM   9092  O O     . SER C 1 319 ? -37.313  -80.661  -18.912 1.00 28.21  ? 319  SER C O     1 
ATOM   9093  C CB    . SER C 1 319 ? -37.750  -83.603  -17.379 1.00 28.35  ? 319  SER C CB    1 
ATOM   9094  O OG    . SER C 1 319 ? -36.831  -82.882  -16.573 1.00 32.42  ? 319  SER C OG    1 
ATOM   9095  N N     . ALA C 1 320 ? -39.415  -81.095  -18.329 1.00 26.73  ? 320  ALA C N     1 
ATOM   9096  C CA    . ALA C 1 320 ? -39.809  -79.700  -18.169 1.00 28.83  ? 320  ALA C CA    1 
ATOM   9097  C C     . ALA C 1 320 ? -39.015  -79.009  -17.057 1.00 28.37  ? 320  ALA C C     1 
ATOM   9098  O O     . ALA C 1 320 ? -38.508  -79.648  -16.135 1.00 29.81  ? 320  ALA C O     1 
ATOM   9099  C CB    . ALA C 1 320 ? -41.287  -79.650  -17.856 1.00 29.41  ? 320  ALA C CB    1 
ATOM   9100  N N     . HIS C 1 321 ? -38.993  -77.674  -17.127 1.00 28.20  ? 321  HIS C N     1 
ATOM   9101  C CA    . HIS C 1 321 ? -38.453  -76.777  -16.123 1.00 27.75  ? 321  HIS C CA    1 
ATOM   9102  C C     . HIS C 1 321 ? -38.897  -77.189  -14.716 1.00 31.82  ? 321  HIS C C     1 
ATOM   9103  O O     . HIS C 1 321 ? -40.081  -77.376  -14.445 1.00 30.41  ? 321  HIS C O     1 
ATOM   9104  C CB    . HIS C 1 321 ? -38.850  -75.335  -16.459 1.00 27.58  ? 321  HIS C CB    1 
ATOM   9105  C CG    . HIS C 1 321 ? -38.416  -74.364  -15.426 1.00 29.86  ? 321  HIS C CG    1 
ATOM   9106  N ND1   . HIS C 1 321 ? -37.153  -73.817  -15.348 1.00 32.90  ? 321  HIS C ND1   1 
ATOM   9107  C CD2   . HIS C 1 321 ? -39.094  -73.898  -14.367 1.00 32.67  ? 321  HIS C CD2   1 
ATOM   9108  C CE1   . HIS C 1 321 ? -37.073  -73.062  -14.258 1.00 33.33  ? 321  HIS C CE1   1 
ATOM   9109  N NE2   . HIS C 1 321 ? -38.243  -73.100  -13.643 1.00 35.24  ? 321  HIS C NE2   1 
ATOM   9110  N N     . GLY C 1 322 ? -37.907  -77.321  -13.825 1.00 30.53  ? 322  GLY C N     1 
ATOM   9111  C CA    . GLY C 1 322 ? -38.160  -77.452  -12.402 1.00 31.09  ? 322  GLY C CA    1 
ATOM   9112  C C     . GLY C 1 322 ? -38.360  -78.893  -11.929 1.00 34.69  ? 322  GLY C C     1 
ATOM   9113  O O     . GLY C 1 322 ? -38.746  -79.083  -10.776 1.00 41.65  ? 322  GLY C O     1 
ATOM   9114  N N     . THR C 1 323 ? -38.135  -79.902  -12.784 1.00 27.36  ? 323  THR C N     1 
ATOM   9115  C CA    . THR C 1 323 ? -38.298  -81.283  -12.349 1.00 25.47  ? 323  THR C CA    1 
ATOM   9116  C C     . THR C 1 323 ? -36.968  -81.984  -12.544 1.00 23.66  ? 323  THR C C     1 
ATOM   9117  O O     . THR C 1 323 ? -36.129  -81.480  -13.277 1.00 23.41  ? 323  THR C O     1 
ATOM   9118  C CB    . THR C 1 323 ? -39.443  -82.005  -13.078 1.00 25.55  ? 323  THR C CB    1 
ATOM   9119  O OG1   . THR C 1 323 ? -38.973  -82.397  -14.363 1.00 29.32  ? 323  THR C OG1   1 
ATOM   9120  C CG2   . THR C 1 323 ? -40.693  -81.166  -13.235 1.00 21.60  ? 323  THR C CG2   1 
ATOM   9121  N N     . ARG C 1 324 ? -36.808  -83.141  -11.904 1.00 25.03  ? 324  ARG C N     1 
ATOM   9122  C CA    . ARG C 1 324 ? -35.605  -83.946  -12.041 1.00 26.44  ? 324  ARG C CA    1 
ATOM   9123  C C     . ARG C 1 324 ? -35.932  -85.214  -12.833 1.00 25.18  ? 324  ARG C C     1 
ATOM   9124  O O     . ARG C 1 324 ? -35.157  -86.173  -12.798 1.00 25.58  ? 324  ARG C O     1 
ATOM   9125  C CB    . ARG C 1 324 ? -35.146  -84.356  -10.632 1.00 27.09  ? 324  ARG C CB    1 
ATOM   9126  C CG    . ARG C 1 324 ? -34.788  -83.162  -9.755  1.00 28.79  ? 324  ARG C CG    1 
ATOM   9127  C CD    . ARG C 1 324 ? -34.127  -83.505  -8.423  1.00 29.29  ? 324  ARG C CD    1 
ATOM   9128  N NE    . ARG C 1 324 ? -35.018  -84.234  -7.514  1.00 29.32  ? 324  ARG C NE    1 
ATOM   9129  C CZ    . ARG C 1 324 ? -34.654  -85.237  -6.718  1.00 27.30  ? 324  ARG C CZ    1 
ATOM   9130  N NH1   . ARG C 1 324 ? -33.419  -85.700  -6.759  1.00 22.68  ? 324  ARG C NH1   1 
ATOM   9131  N NH2   . ARG C 1 324 ? -35.528  -85.795  -5.885  1.00 23.43  ? 324  ARG C NH2   1 
ATOM   9132  N N     . ASP C 1 325 ? -37.105  -85.249  -13.489 1.00 22.79  ? 325  ASP C N     1 
ATOM   9133  C CA    . ASP C 1 325 ? -37.550  -86.453  -14.183 1.00 20.07  ? 325  ASP C CA    1 
ATOM   9134  C C     . ASP C 1 325 ? -36.624  -86.716  -15.387 1.00 22.40  ? 325  ASP C C     1 
ATOM   9135  O O     . ASP C 1 325 ? -35.980  -85.778  -15.903 1.00 20.06  ? 325  ASP C O     1 
ATOM   9136  C CB    . ASP C 1 325 ? -38.999  -86.244  -14.589 1.00 19.85  ? 325  ASP C CB    1 
ATOM   9137  C CG    . ASP C 1 325 ? -39.954  -85.901  -13.450 1.00 28.14  ? 325  ASP C CG    1 
ATOM   9138  O OD1   . ASP C 1 325 ? -39.619  -86.212  -12.249 1.00 29.09  ? 325  ASP C OD1   1 
ATOM   9139  O OD2   . ASP C 1 325 ? -41.034  -85.296  -13.749 1.00 24.16  ? 325  ASP C OD2   1 
ATOM   9140  N N     . PHE C 1 326 ? -36.569  -87.969  -15.867 1.00 18.26  ? 326  PHE C N     1 
ATOM   9141  C CA    . PHE C 1 326 ? -35.759  -88.264  -17.046 1.00 18.35  ? 326  PHE C CA    1 
ATOM   9142  C C     . PHE C 1 326 ? -36.335  -89.488  -17.755 1.00 21.52  ? 326  PHE C C     1 
ATOM   9143  O O     . PHE C 1 326 ? -37.253  -90.152  -17.223 1.00 22.20  ? 326  PHE C O     1 
ATOM   9144  C CB    . PHE C 1 326 ? -34.288  -88.477  -16.667 1.00 20.16  ? 326  PHE C CB    1 
ATOM   9145  C CG    . PHE C 1 326 ? -34.025  -89.657  -15.721 1.00 21.34  ? 326  PHE C CG    1 
ATOM   9146  C CD1   . PHE C 1 326 ? -33.787  -90.936  -16.219 1.00 20.87  ? 326  PHE C CD1   1 
ATOM   9147  C CD2   . PHE C 1 326 ? -34.007  -89.477  -14.336 1.00 20.45  ? 326  PHE C CD2   1 
ATOM   9148  C CE1   . PHE C 1 326 ? -33.513  -92.004  -15.352 1.00 25.96  ? 326  PHE C CE1   1 
ATOM   9149  C CE2   . PHE C 1 326 ? -33.733  -90.547  -13.480 1.00 21.63  ? 326  PHE C CE2   1 
ATOM   9150  C CZ    . PHE C 1 326 ? -33.493  -91.816  -13.982 1.00 22.21  ? 326  PHE C CZ    1 
ATOM   9151  N N     . VAL C 1 327 ? -35.768  -89.811  -18.938 1.00 21.57  ? 327  VAL C N     1 
ATOM   9152  C CA    . VAL C 1 327 ? -36.288  -90.895  -19.766 1.00 22.96  ? 327  VAL C CA    1 
ATOM   9153  C C     . VAL C 1 327 ? -35.194  -91.919  -20.077 1.00 22.05  ? 327  VAL C C     1 
ATOM   9154  O O     . VAL C 1 327 ? -34.053  -91.549  -20.298 1.00 21.43  ? 327  VAL C O     1 
ATOM   9155  C CB    . VAL C 1 327 ? -36.859  -90.272  -21.053 1.00 24.32  ? 327  VAL C CB    1 
ATOM   9156  C CG1   . VAL C 1 327 ? -37.483  -91.335  -21.957 1.00 24.31  ? 327  VAL C CG1   1 
ATOM   9157  C CG2   . VAL C 1 327 ? -37.850  -89.157  -20.740 1.00 20.48  ? 327  VAL C CG2   1 
ATOM   9158  N N     . LEU C 1 328 ? -35.549  -93.205  -20.100 1.00 22.08  ? 328  LEU C N     1 
ATOM   9159  C CA    . LEU C 1 328 ? -34.660  -94.276  -20.530 1.00 25.47  ? 328  LEU C CA    1 
ATOM   9160  C C     . LEU C 1 328 ? -35.309  -95.016  -21.702 1.00 27.98  ? 328  LEU C C     1 
ATOM   9161  O O     . LEU C 1 328 ? -36.526  -95.229  -21.727 1.00 29.50  ? 328  LEU C O     1 
ATOM   9162  C CB    . LEU C 1 328 ? -34.371  -95.229  -19.364 1.00 27.27  ? 328  LEU C CB    1 
ATOM   9163  C CG    . LEU C 1 328 ? -33.508  -94.665  -18.220 1.00 28.55  ? 328  LEU C CG    1 
ATOM   9164  C CD1   . LEU C 1 328 ? -33.423  -95.619  -17.009 1.00 21.02  ? 328  LEU C CD1   1 
ATOM   9165  C CD2   . LEU C 1 328 ? -32.115  -94.275  -18.743 1.00 20.43  ? 328  LEU C CD2   1 
ATOM   9166  N N     . HIS C 1 329 ? -34.484  -95.431  -22.663 1.00 29.70  ? 329  HIS C N     1 
ATOM   9167  C CA    . HIS C 1 329 ? -34.925  -96.057  -23.906 1.00 28.16  ? 329  HIS C CA    1 
ATOM   9168  C C     . HIS C 1 329 ? -34.472  -97.519  -23.934 1.00 27.32  ? 329  HIS C C     1 
ATOM   9169  O O     . HIS C 1 329 ? -33.317  -97.819  -23.640 1.00 30.13  ? 329  HIS C O     1 
ATOM   9170  C CB    . HIS C 1 329 ? -34.355  -95.243  -25.075 1.00 30.66  ? 329  HIS C CB    1 
ATOM   9171  C CG    . HIS C 1 329 ? -34.579  -95.877  -26.408 1.00 40.32  ? 329  HIS C CG    1 
ATOM   9172  N ND1   . HIS C 1 329 ? -35.789  -95.783  -27.081 1.00 43.13  ? 329  HIS C ND1   1 
ATOM   9173  C CD2   . HIS C 1 329 ? -33.749  -96.619  -27.192 1.00 36.08  ? 329  HIS C CD2   1 
ATOM   9174  C CE1   . HIS C 1 329 ? -35.695  -96.436  -28.231 1.00 39.36  ? 329  HIS C CE1   1 
ATOM   9175  N NE2   . HIS C 1 329 ? -34.469  -96.955  -28.311 1.00 42.55  ? 329  HIS C NE2   1 
ATOM   9176  N N     . THR C 1 330 ? -35.385  -98.439  -24.236 1.00 27.97  ? 330  THR C N     1 
ATOM   9177  C CA    . THR C 1 330 ? -35.013  -99.774  -24.694 1.00 29.50  ? 330  THR C CA    1 
ATOM   9178  C C     . THR C 1 330 ? -35.522  -99.898  -26.125 1.00 34.44  ? 330  THR C C     1 
ATOM   9179  O O     . THR C 1 330 ? -36.143  -98.966  -26.642 1.00 36.31  ? 330  THR C O     1 
ATOM   9180  C CB    . THR C 1 330 ? -35.584  -100.877 -23.803 1.00 28.81  ? 330  THR C CB    1 
ATOM   9181  O OG1   . THR C 1 330 ? -36.999  -100.867 -24.037 1.00 28.09  ? 330  THR C OG1   1 
ATOM   9182  C CG2   . THR C 1 330 ? -35.213  -100.694 -22.335 1.00 26.46  ? 330  THR C CG2   1 
ATOM   9183  N N     . SER C 1 331 ? -35.251  -101.020 -26.796 1.00 39.70  ? 331  SER C N     1 
ATOM   9184  C CA    . SER C 1 331 ? -35.638  -101.035 -28.210 1.00 49.97  ? 331  SER C CA    1 
ATOM   9185  C C     . SER C 1 331 ? -37.160  -101.098 -28.376 1.00 41.64  ? 331  SER C C     1 
ATOM   9186  O O     . SER C 1 331 ? -37.662  -100.622 -29.374 1.00 43.35  ? 331  SER C O     1 
ATOM   9187  C CB    . SER C 1 331 ? -34.931  -102.075 -29.036 1.00 44.79  ? 331  SER C CB    1 
ATOM   9188  O OG    . SER C 1 331 ? -35.263  -103.312 -28.445 1.00 48.27  ? 331  SER C OG    1 
ATOM   9189  N N     . LYS C 1 332 ? -37.885  -101.617 -27.378 1.00 38.56  ? 332  LYS C N     1 
ATOM   9190  C CA    . LYS C 1 332 ? -39.334  -101.744 -27.454 1.00 47.02  ? 332  LYS C CA    1 
ATOM   9191  C C     . LYS C 1 332 ? -40.112  -100.617 -26.753 1.00 44.85  ? 332  LYS C C     1 
ATOM   9192  O O     . LYS C 1 332 ? -41.270  -100.391 -27.088 1.00 44.12  ? 332  LYS C O     1 
ATOM   9193  C CB    . LYS C 1 332 ? -39.754  -103.140 -26.990 1.00 63.41  ? 332  LYS C CB    1 
ATOM   9194  C CG    . LYS C 1 332 ? -39.777  -104.045 -28.223 1.00 79.99  ? 332  LYS C CG    1 
ATOM   9195  C CD    . LYS C 1 332 ? -39.922  -105.546 -28.086 1.00 100.31 ? 332  LYS C CD    1 
ATOM   9196  C CE    . LYS C 1 332 ? -39.871  -106.046 -29.502 1.00 94.31  ? 332  LYS C CE    1 
ATOM   9197  N NZ    . LYS C 1 332 ? -40.356  -107.420 -29.587 1.00 90.42  ? 332  LYS C NZ    1 
ATOM   9198  N N     . HIS C 1 333 ? -39.509  -99.917  -25.780 1.00 34.83  ? 333  HIS C N     1 
ATOM   9199  C CA    . HIS C 1 333 ? -40.267  -98.969  -24.973 1.00 31.84  ? 333  HIS C CA    1 
ATOM   9200  C C     . HIS C 1 333 ? -39.406  -97.788  -24.528 1.00 31.27  ? 333  HIS C C     1 
ATOM   9201  O O     . HIS C 1 333 ? -38.181  -97.866  -24.509 1.00 33.62  ? 333  HIS C O     1 
ATOM   9202  C CB    . HIS C 1 333 ? -40.808  -99.641  -23.718 1.00 30.97  ? 333  HIS C CB    1 
ATOM   9203  C CG    . HIS C 1 333 ? -41.705  -100.816 -23.965 1.00 36.39  ? 333  HIS C CG    1 
ATOM   9204  N ND1   . HIS C 1 333 ? -43.017  -100.693 -24.381 1.00 35.75  ? 333  HIS C ND1   1 
ATOM   9205  C CD2   . HIS C 1 333 ? -41.485  -102.145 -23.837 1.00 36.43  ? 333  HIS C CD2   1 
ATOM   9206  C CE1   . HIS C 1 333 ? -43.559  -101.901 -24.501 1.00 35.34  ? 333  HIS C CE1   1 
ATOM   9207  N NE2   . HIS C 1 333 ? -42.650  -102.795 -24.171 1.00 35.37  ? 333  HIS C NE2   1 
ATOM   9208  N N     . ASP C 1 334 ? -40.069  -96.675  -24.223 1.00 29.00  ? 334  ASP C N     1 
ATOM   9209  C CA    . ASP C 1 334 ? -39.458  -95.638  -23.410 1.00 28.66  ? 334  ASP C CA    1 
ATOM   9210  C C     . ASP C 1 334 ? -40.019  -95.728  -21.994 1.00 26.88  ? 334  ASP C C     1 
ATOM   9211  O O     . ASP C 1 334 ? -41.128  -96.234  -21.799 1.00 27.23  ? 334  ASP C O     1 
ATOM   9212  C CB    . ASP C 1 334 ? -39.546  -94.266  -24.053 1.00 27.82  ? 334  ASP C CB    1 
ATOM   9213  C CG    . ASP C 1 334 ? -38.714  -94.134  -25.322 1.00 32.42  ? 334  ASP C CG    1 
ATOM   9214  O OD1   . ASP C 1 334 ? -37.598  -94.679  -25.369 1.00 32.07  ? 334  ASP C OD1   1 
ATOM   9215  O OD2   . ASP C 1 334 ? -39.194  -93.503  -26.283 1.00 33.28  ? 334  ASP C OD2   1 
ATOM   9216  N N     . PHE C 1 335 ? -39.236  -95.254  -21.019 1.00 25.28  ? 335  PHE C N     1 
ATOM   9217  C CA    . PHE C 1 335 ? -39.650  -95.279  -19.619 1.00 24.04  ? 335  PHE C CA    1 
ATOM   9218  C C     . PHE C 1 335 ? -39.425  -93.891  -19.033 1.00 23.78  ? 335  PHE C C     1 
ATOM   9219  O O     . PHE C 1 335 ? -38.338  -93.328  -19.186 1.00 24.61  ? 335  PHE C O     1 
ATOM   9220  C CB    . PHE C 1 335 ? -38.840  -96.348  -18.871 1.00 23.26  ? 335  PHE C CB    1 
ATOM   9221  C CG    . PHE C 1 335 ? -39.056  -97.783  -19.345 1.00 21.02  ? 335  PHE C CG    1 
ATOM   9222  C CD1   . PHE C 1 335 ? -38.383  -98.288  -20.452 1.00 19.91  ? 335  PHE C CD1   1 
ATOM   9223  C CD2   . PHE C 1 335 ? -39.936  -98.629  -18.671 1.00 20.26  ? 335  PHE C CD2   1 
ATOM   9224  C CE1   . PHE C 1 335 ? -38.583  -99.614  -20.852 1.00 20.87  ? 335  PHE C CE1   1 
ATOM   9225  C CE2   . PHE C 1 335 ? -40.136  -99.946  -19.063 1.00 20.90  ? 335  PHE C CE2   1 
ATOM   9226  C CZ    . PHE C 1 335 ? -39.455  -100.444 -20.161 1.00 20.14  ? 335  PHE C CZ    1 
ATOM   9227  N N     . LEU C 1 336 ? -40.480  -93.347  -18.414 1.00 21.82  ? 336  LEU C N     1 
ATOM   9228  C CA    . LEU C 1 336 ? -40.432  -92.105  -17.668 1.00 20.04  ? 336  LEU C CA    1 
ATOM   9229  C C     . LEU C 1 336 ? -40.055  -92.446  -16.229 1.00 21.52  ? 336  LEU C C     1 
ATOM   9230  O O     . LEU C 1 336 ? -40.712  -93.271  -15.580 1.00 21.36  ? 336  LEU C O     1 
ATOM   9231  C CB    . LEU C 1 336 ? -41.796  -91.419  -17.708 1.00 19.50  ? 336  LEU C CB    1 
ATOM   9232  C CG    . LEU C 1 336 ? -42.360  -91.174  -19.114 1.00 21.83  ? 336  LEU C CG    1 
ATOM   9233  C CD1   . LEU C 1 336 ? -43.744  -90.547  -19.043 1.00 19.29  ? 336  LEU C CD1   1 
ATOM   9234  C CD2   . LEU C 1 336 ? -41.437  -90.318  -19.989 1.00 20.92  ? 336  LEU C CD2   1 
ATOM   9235  N N     . CYS C 1 337 ? -38.939  -91.861  -15.774 1.00 21.69  ? 337  CYS C N     1 
ATOM   9236  C CA    . CYS C 1 337 ? -38.465  -92.019  -14.412 1.00 21.26  ? 337  CYS C CA    1 
ATOM   9237  C C     . CYS C 1 337 ? -38.805  -90.726  -13.682 1.00 22.97  ? 337  CYS C C     1 
ATOM   9238  O O     . CYS C 1 337 ? -38.266  -89.665  -13.991 1.00 23.73  ? 337  CYS C O     1 
ATOM   9239  C CB    . CYS C 1 337 ? -36.974  -92.339  -14.384 1.00 22.41  ? 337  CYS C CB    1 
ATOM   9240  S SG    . CYS C 1 337 ? -36.587  -93.878  -15.276 1.00 26.47  ? 337  CYS C SG    1 
ATOM   9241  N N     . ILE C 1 338 ? -39.739  -90.824  -12.740 1.00 21.43  ? 338  ILE C N     1 
ATOM   9242  C CA    . ILE C 1 338 ? -40.355  -89.633  -12.195 1.00 22.54  ? 338  ILE C CA    1 
ATOM   9243  C C     . ILE C 1 338 ? -40.044  -89.525  -10.703 1.00 20.68  ? 338  ILE C C     1 
ATOM   9244  O O     . ILE C 1 338 ? -40.225  -90.490  -9.975  1.00 22.16  ? 338  ILE C O     1 
ATOM   9245  C CB    . ILE C 1 338 ? -41.852  -89.652  -12.549 1.00 22.97  ? 338  ILE C CB    1 
ATOM   9246  C CG1   . ILE C 1 338 ? -41.976  -89.456  -14.061 1.00 24.92  ? 338  ILE C CG1   1 
ATOM   9247  C CG2   . ILE C 1 338 ? -42.578  -88.541  -11.790 1.00 21.81  ? 338  ILE C CG2   1 
ATOM   9248  C CD1   . ILE C 1 338 ? -43.377  -89.522  -14.605 1.00 27.85  ? 338  ILE C CD1   1 
ATOM   9249  N N     . LEU C 1 339 ? -39.510  -88.359  -10.302 1.00 20.94  ? 339  LEU C N     1 
ATOM   9250  C CA    . LEU C 1 339 ? -39.042  -88.101  -8.947  1.00 22.60  ? 339  LEU C CA    1 
ATOM   9251  C C     . LEU C 1 339 ? -39.976  -87.104  -8.241  1.00 24.12  ? 339  LEU C C     1 
ATOM   9252  O O     . LEU C 1 339 ? -40.799  -86.439  -8.889  1.00 23.19  ? 339  LEU C O     1 
ATOM   9253  C CB    . LEU C 1 339 ? -37.595  -87.601  -8.964  1.00 19.64  ? 339  LEU C CB    1 
ATOM   9254  C CG    . LEU C 1 339 ? -36.526  -88.670  -9.230  1.00 21.10  ? 339  LEU C CG    1 
ATOM   9255  C CD1   . LEU C 1 339 ? -36.472  -89.118  -10.707 1.00 18.10  ? 339  LEU C CD1   1 
ATOM   9256  C CD2   . LEU C 1 339 ? -35.119  -88.236  -8.748  1.00 18.15  ? 339  LEU C CD2   1 
ATOM   9257  N N     . ASP C 1 340 ? -39.842  -87.014  -6.897  1.00 22.97  ? 340  ASP C N     1 
ATOM   9258  C CA    . ASP C 1 340 ? -40.536  -86.003  -6.109  1.00 24.46  ? 340  ASP C CA    1 
ATOM   9259  C C     . ASP C 1 340 ? -42.042  -86.210  -6.182  1.00 22.78  ? 340  ASP C C     1 
ATOM   9260  O O     . ASP C 1 340 ? -42.766  -85.233  -6.258  1.00 28.00  ? 340  ASP C O     1 
ATOM   9261  C CB    . ASP C 1 340 ? -40.132  -84.586  -6.507  1.00 23.82  ? 340  ASP C CB    1 
ATOM   9262  C CG    . ASP C 1 340 ? -38.617  -84.392  -6.523  1.00 31.06  ? 340  ASP C CG    1 
ATOM   9263  O OD1   . ASP C 1 340 ? -38.000  -84.605  -5.447  1.00 32.69  ? 340  ASP C OD1   1 
ATOM   9264  O OD2   . ASP C 1 340 ? -38.029  -84.095  -7.606  1.00 31.67  ? 340  ASP C OD2   1 
ATOM   9265  N N     . LEU C 1 341 ? -42.507  -87.461  -6.147  1.00 21.05  ? 341  LEU C N     1 
ATOM   9266  C CA    . LEU C 1 341 ? -43.923  -87.726  -6.032  1.00 24.36  ? 341  LEU C CA    1 
ATOM   9267  C C     . LEU C 1 341 ? -44.305  -87.822  -4.564  1.00 23.34  ? 341  LEU C C     1 
ATOM   9268  O O     . LEU C 1 341 ? -43.486  -88.224  -3.731  1.00 23.87  ? 341  LEU C O     1 
ATOM   9269  C CB    . LEU C 1 341 ? -44.295  -89.017  -6.762  1.00 23.04  ? 341  LEU C CB    1 
ATOM   9270  C CG    . LEU C 1 341 ? -44.220  -88.937  -8.287  1.00 26.53  ? 341  LEU C CG    1 
ATOM   9271  C CD1   . LEU C 1 341 ? -44.552  -90.284  -8.862  1.00 21.36  ? 341  LEU C CD1   1 
ATOM   9272  C CD2   . LEU C 1 341 ? -45.152  -87.888  -8.854  1.00 20.20  ? 341  LEU C CD2   1 
ATOM   9273  N N     . GLN C 1 342 ? -45.588  -87.549  -4.293  1.00 23.82  ? 342  GLN C N     1 
ATOM   9274  C CA    . GLN C 1 342 ? -46.070  -87.742  -2.934  1.00 25.66  ? 342  GLN C CA    1 
ATOM   9275  C C     . GLN C 1 342 ? -47.121  -88.843  -2.856  1.00 25.56  ? 342  GLN C C     1 
ATOM   9276  O O     . GLN C 1 342 ? -47.589  -89.341  -3.879  1.00 27.93  ? 342  GLN C O     1 
ATOM   9277  C CB    . GLN C 1 342 ? -46.492  -86.373  -2.438  1.00 27.93  ? 342  GLN C CB    1 
ATOM   9278  C CG    . GLN C 1 342 ? -45.267  -85.510  -2.159  1.00 33.24  ? 342  GLN C CG    1 
ATOM   9279  C CD    . GLN C 1 342 ? -45.700  -84.143  -1.703  1.00 42.85  ? 342  GLN C CD    1 
ATOM   9280  O OE1   . GLN C 1 342 ? -46.209  -83.334  -2.486  1.00 49.68  ? 342  GLN C OE1   1 
ATOM   9281  N NE2   . GLN C 1 342 ? -45.593  -83.928  -0.403  1.00 49.35  ? 342  GLN C NE2   1 
ATOM   9282  N N     . VAL C 1 343 ? -47.469  -89.212  -1.623  1.00 22.75  ? 343  VAL C N     1 
ATOM   9283  C CA    . VAL C 1 343 ? -48.481  -90.217  -1.366  1.00 24.57  ? 343  VAL C CA    1 
ATOM   9284  C C     . VAL C 1 343 ? -49.878  -89.594  -1.457  1.00 27.86  ? 343  VAL C C     1 
ATOM   9285  O O     . VAL C 1 343 ? -50.079  -88.411  -1.139  1.00 30.84  ? 343  VAL C O     1 
ATOM   9286  C CB    . VAL C 1 343 ? -48.209  -90.852  0.009   1.00 23.67  ? 343  VAL C CB    1 
ATOM   9287  C CG1   . VAL C 1 343 ? -49.214  -91.945  0.329   1.00 26.31  ? 343  VAL C CG1   1 
ATOM   9288  C CG2   . VAL C 1 343 ? -46.759  -91.346  0.148   1.00 21.03  ? 343  VAL C CG2   1 
ATOM   9289  N N     . VAL C 1 344 ? -50.838  -90.382  -1.965  1.00 27.44  ? 344  VAL C N     1 
ATOM   9290  C CA    . VAL C 1 344 ? -52.222  -89.948  -2.107  1.00 29.95  ? 344  VAL C CA    1 
ATOM   9291  C C     . VAL C 1 344 ? -53.037  -90.382  -0.877  1.00 31.81  ? 344  VAL C C     1 
ATOM   9292  O O     . VAL C 1 344 ? -53.123  -91.579  -0.603  1.00 39.05  ? 344  VAL C O     1 
ATOM   9293  C CB    . VAL C 1 344 ? -52.791  -90.616  -3.378  1.00 34.76  ? 344  VAL C CB    1 
ATOM   9294  C CG1   . VAL C 1 344 ? -54.317  -90.492  -3.497  1.00 34.97  ? 344  VAL C CG1   1 
ATOM   9295  C CG2   . VAL C 1 344 ? -52.099  -90.137  -4.654  1.00 29.84  ? 344  VAL C CG2   1 
ATOM   9296  N N     . GLY C 1 345 ? -53.652  -89.420  -0.167  1.00 33.92  ? 345  GLY C N     1 
ATOM   9297  C CA    . GLY C 1 345 ? -54.660  -89.638  0.874   1.00 38.74  ? 345  GLY C CA    1 
ATOM   9298  C C     . GLY C 1 345 ? -56.080  -89.814  0.301   1.00 49.77  ? 345  GLY C C     1 
ATOM   9299  O O     . GLY C 1 345 ? -56.293  -90.462  -0.730  1.00 51.71  ? 345  GLY C O     1 
ATOM   9300  N N     . LYS C 1 346 ? -57.085  -89.230  0.971   1.00 54.58  ? 346  LYS C N     1 
ATOM   9301  C CA    . LYS C 1 346 ? -58.478  -89.437  0.599   1.00 61.22  ? 346  LYS C CA    1 
ATOM   9302  C C     . LYS C 1 346 ? -59.326  -88.414  1.339   1.00 67.63  ? 346  LYS C C     1 
ATOM   9303  O O     . LYS C 1 346 ? -59.165  -88.272  2.545   1.00 62.06  ? 346  LYS C O     1 
ATOM   9304  C CB    . LYS C 1 346 ? -59.044  -90.829  0.932   1.00 56.44  ? 346  LYS C CB    1 
ATOM   9305  C CG    . LYS C 1 346 ? -60.373  -91.109  0.241   1.00 65.50  ? 346  LYS C CG    1 
ATOM   9306  C CD    . LYS C 1 346 ? -61.076  -92.428  0.541   1.00 72.39  ? 346  LYS C CD    1 
ATOM   9307  C CE    . LYS C 1 346 ? -61.966  -92.886  -0.577  1.00 69.53  ? 346  LYS C CE    1 
ATOM   9308  N NZ    . LYS C 1 346 ? -61.763  -94.323  -0.814  1.00 62.67  ? 346  LYS C NZ    1 
ATOM   9309  N N     . ASP C 1 347 ? -60.224  -87.728  0.599   1.00 79.58  ? 347  ASP C N     1 
ATOM   9310  C CA    . ASP C 1 347 ? -61.182  -86.752  1.111   1.00 78.52  ? 347  ASP C CA    1 
ATOM   9311  C C     . ASP C 1 347 ? -60.440  -85.664  1.897   1.00 76.24  ? 347  ASP C C     1 
ATOM   9312  O O     . ASP C 1 347 ? -59.654  -84.902  1.339   1.00 76.68  ? 347  ASP C O     1 
ATOM   9313  C CB    . ASP C 1 347 ? -62.339  -87.384  1.888   1.00 83.45  ? 347  ASP C CB    1 
ATOM   9314  C CG    . ASP C 1 347 ? -63.116  -88.505  1.204   1.00 88.23  ? 347  ASP C CG    1 
ATOM   9315  O OD1   . ASP C 1 347 ? -63.478  -88.328  0.026   1.00 80.60  ? 347  ASP C OD1   1 
ATOM   9316  O OD2   . ASP C 1 347 ? -63.347  -89.558  1.854   1.00 86.72  ? 347  ASP C OD2   1 
ATOM   9317  N N     . ASN C 1 348 ? -60.684  -85.612  3.211   1.00 77.64  ? 348  ASN C N     1 
ATOM   9318  C CA    . ASN C 1 348 ? -60.146  -84.572  4.077   1.00 86.28  ? 348  ASN C CA    1 
ATOM   9319  C C     . ASN C 1 348 ? -58.690  -84.853  4.441   1.00 80.08  ? 348  ASN C C     1 
ATOM   9320  O O     . ASN C 1 348 ? -58.017  -83.946  4.911   1.00 83.09  ? 348  ASN C O     1 
ATOM   9321  C CB    . ASN C 1 348 ? -61.086  -84.190  5.219   1.00 98.65  ? 348  ASN C CB    1 
ATOM   9322  C CG    . ASN C 1 348 ? -61.515  -85.357  6.084   1.00 115.59 ? 348  ASN C CG    1 
ATOM   9323  O OD1   . ASN C 1 348 ? -61.831  -86.467  5.612   1.00 112.71 ? 348  ASN C OD1   1 
ATOM   9324  N ND2   . ASN C 1 348 ? -61.572  -85.096  7.386   1.00 113.57 ? 348  ASN C ND2   1 
ATOM   9325  N N     . VAL C 1 349 ? -58.209  -86.088  4.225   1.00 76.00  ? 349  VAL C N     1 
ATOM   9326  C CA    . VAL C 1 349 ? -56.843  -86.483  4.566   1.00 66.57  ? 349  VAL C CA    1 
ATOM   9327  C C     . VAL C 1 349 ? -55.923  -86.246  3.364   1.00 59.05  ? 349  VAL C C     1 
ATOM   9328  O O     . VAL C 1 349 ? -55.937  -87.020  2.393   1.00 59.70  ? 349  VAL C O     1 
ATOM   9329  C CB    . VAL C 1 349 ? -56.730  -87.929  5.096   1.00 62.01  ? 349  VAL C CB    1 
ATOM   9330  C CG1   . VAL C 1 349 ? -55.354  -88.195  5.732   1.00 60.84  ? 349  VAL C CG1   1 
ATOM   9331  C CG2   . VAL C 1 349 ? -57.869  -88.243  6.060   1.00 60.27  ? 349  VAL C CG2   1 
ATOM   9332  N N     . VAL C 1 350 ? -55.133  -85.162  3.460   1.00 48.02  ? 350  VAL C N     1 
ATOM   9333  C CA    . VAL C 1 350 ? -54.321  -84.661  2.362   1.00 53.89  ? 350  VAL C CA    1 
ATOM   9334  C C     . VAL C 1 350 ? -52.853  -84.992  2.655   1.00 54.37  ? 350  VAL C C     1 
ATOM   9335  O O     . VAL C 1 350 ? -52.303  -84.507  3.642   1.00 55.62  ? 350  VAL C O     1 
ATOM   9336  C CB    . VAL C 1 350 ? -54.561  -83.145  2.159   1.00 52.33  ? 350  VAL C CB    1 
ATOM   9337  C CG1   . VAL C 1 350 ? -53.588  -82.479  1.175   1.00 50.20  ? 350  VAL C CG1   1 
ATOM   9338  C CG2   . VAL C 1 350 ? -56.007  -82.840  1.748   1.00 50.15  ? 350  VAL C CG2   1 
ATOM   9339  N N     . LEU C 1 351 ? -52.234  -85.821  1.796   1.00 52.55  ? 351  LEU C N     1 
ATOM   9340  C CA    . LEU C 1 351 ? -50.842  -86.232  1.971   1.00 56.13  ? 351  LEU C CA    1 
ATOM   9341  C C     . LEU C 1 351 ? -49.901  -85.555  0.957   1.00 51.80  ? 351  LEU C C     1 
ATOM   9342  O O     . LEU C 1 351 ? -48.685  -85.622  1.123   1.00 48.54  ? 351  LEU C O     1 
ATOM   9343  C CB    . LEU C 1 351 ? -50.710  -87.758  2.001   1.00 49.94  ? 351  LEU C CB    1 
ATOM   9344  C CG    . LEU C 1 351 ? -51.552  -88.486  3.056   1.00 50.31  ? 351  LEU C CG    1 
ATOM   9345  C CD1   . LEU C 1 351 ? -51.499  -89.991  2.792   1.00 40.12  ? 351  LEU C CD1   1 
ATOM   9346  C CD2   . LEU C 1 351 ? -51.143  -88.138  4.509   1.00 38.37  ? 351  LEU C CD2   1 
ATOM   9347  N N     . GLY C 1 352 ? -50.454  -84.897  -0.083  1.00 47.69  ? 352  GLY C N     1 
ATOM   9348  C CA    . GLY C 1 352 ? -49.668  -84.110  -1.029  1.00 49.15  ? 352  GLY C CA    1 
ATOM   9349  C C     . GLY C 1 352 ? -49.814  -84.572  -2.486  1.00 48.85  ? 352  GLY C C     1 
ATOM   9350  O O     . GLY C 1 352 ? -49.607  -83.774  -3.392  1.00 43.35  ? 352  GLY C O     1 
ATOM   9351  N N     . GLY C 1 353 ? -50.182  -85.850  -2.717  1.00 48.37  ? 353  GLY C N     1 
ATOM   9352  C CA    . GLY C 1 353 ? -50.119  -86.424  -4.052  1.00 42.90  ? 353  GLY C CA    1 
ATOM   9353  C C     . GLY C 1 353 ? -51.445  -86.373  -4.827  1.00 47.64  ? 353  GLY C C     1 
ATOM   9354  O O     . GLY C 1 353 ? -51.489  -86.853  -5.969  1.00 40.71  ? 353  GLY C O     1 
ATOM   9355  N N     . GLU C 1 354 ? -52.505  -85.765  -4.255  1.00 42.95  ? 354  GLU C N     1 
ATOM   9356  C CA    . GLU C 1 354 ? -53.854  -86.008  -4.775  1.00 48.48  ? 354  GLU C CA    1 
ATOM   9357  C C     . GLU C 1 354 ? -54.240  -85.154  -5.996  1.00 45.69  ? 354  GLU C C     1 
ATOM   9358  O O     . GLU C 1 354 ? -55.037  -85.631  -6.815  1.00 41.56  ? 354  GLU C O     1 
ATOM   9359  C CB    . GLU C 1 354 ? -54.977  -86.287  -3.764  1.00 53.02  ? 354  GLU C CB    1 
ATOM   9360  C CG    . GLU C 1 354 ? -54.939  -85.447  -2.489  1.00 57.00  ? 354  GLU C CG    1 
ATOM   9361  C CD    . GLU C 1 354 ? -53.781  -85.659  -1.518  1.00 60.03  ? 354  GLU C CD    1 
ATOM   9362  O OE1   . GLU C 1 354 ? -52.881  -84.777  -1.507  1.00 59.57  ? 354  GLU C OE1   1 
ATOM   9363  O OE2   . GLU C 1 354 ? -53.776  -86.664  -0.756  1.00 46.06  ? 354  GLU C OE2   1 
ATOM   9364  N N     . GLY C 1 355 ? -53.694  -83.925  -6.163  1.00 37.36  ? 355  GLY C N     1 
ATOM   9365  C CA    . GLY C 1 355 ? -54.117  -83.128  -7.316  1.00 30.59  ? 355  GLY C CA    1 
ATOM   9366  C C     . GLY C 1 355 ? -53.528  -83.693  -8.615  1.00 29.85  ? 355  GLY C C     1 
ATOM   9367  O O     . GLY C 1 355 ? -52.544  -84.433  -8.592  1.00 30.19  ? 355  GLY C O     1 
ATOM   9368  N N     . VAL C 1 356 ? -54.122  -83.357  -9.764  1.00 25.41  ? 356  VAL C N     1 
ATOM   9369  C CA    . VAL C 1 356 ? -53.479  -83.658  -11.031 1.00 25.73  ? 356  VAL C CA    1 
ATOM   9370  C C     . VAL C 1 356 ? -52.063  -83.058  -11.052 1.00 26.65  ? 356  VAL C C     1 
ATOM   9371  O O     . VAL C 1 356 ? -51.843  -81.917  -10.623 1.00 25.85  ? 356  VAL C O     1 
ATOM   9372  C CB    . VAL C 1 356 ? -54.384  -83.068  -12.121 1.00 23.21  ? 356  VAL C CB    1 
ATOM   9373  C CG1   . VAL C 1 356 ? -53.753  -83.184  -13.511 1.00 18.32  ? 356  VAL C CG1   1 
ATOM   9374  C CG2   . VAL C 1 356 ? -55.781  -83.719  -12.058 1.00 19.59  ? 356  VAL C CG2   1 
ATOM   9375  N N     . ASN C 1 357 ? -51.102  -83.826  -11.588 1.00 21.57  ? 357  ASN C N     1 
ATOM   9376  C CA    . ASN C 1 357 ? -49.689  -83.503  -11.465 1.00 20.30  ? 357  ASN C CA    1 
ATOM   9377  C C     . ASN C 1 357 ? -49.037  -83.595  -12.846 1.00 21.35  ? 357  ASN C C     1 
ATOM   9378  O O     . ASN C 1 357 ? -48.418  -84.604  -13.204 1.00 20.35  ? 357  ASN C O     1 
ATOM   9379  C CB    . ASN C 1 357 ? -49.062  -84.458  -10.447 1.00 22.91  ? 357  ASN C CB    1 
ATOM   9380  C CG    . ASN C 1 357 ? -47.564  -84.315  -10.289 1.00 27.14  ? 357  ASN C CG    1 
ATOM   9381  O OD1   . ASN C 1 357 ? -46.965  -83.273  -10.607 1.00 26.55  ? 357  ASN C OD1   1 
ATOM   9382  N ND2   . ASN C 1 357 ? -46.929  -85.380  -9.828  1.00 29.40  ? 357  ASN C ND2   1 
ATOM   9383  N N     . PRO C 1 358 ? -49.186  -82.565  -13.707 1.00 22.12  ? 358  PRO C N     1 
ATOM   9384  C CA    . PRO C 1 358 ? -48.650  -82.644  -15.062 1.00 21.89  ? 358  PRO C CA    1 
ATOM   9385  C C     . PRO C 1 358 ? -47.132  -82.611  -15.120 1.00 21.68  ? 358  PRO C C     1 
ATOM   9386  O O     . PRO C 1 358 ? -46.542  -81.633  -14.700 1.00 27.71  ? 358  PRO C O     1 
ATOM   9387  C CB    . PRO C 1 358 ? -49.291  -81.484  -15.832 1.00 22.25  ? 358  PRO C CB    1 
ATOM   9388  C CG    . PRO C 1 358 ? -49.810  -80.616  -14.725 1.00 21.87  ? 358  PRO C CG    1 
ATOM   9389  C CD    . PRO C 1 358 ? -49.920  -81.330  -13.435 1.00 18.57  ? 358  PRO C CD    1 
ATOM   9390  N N     . ARG C 1 359 ? -46.509  -83.684  -15.634 1.00 20.04  ? 359  ARG C N     1 
ATOM   9391  C CA    . ARG C 1 359 ? -45.076  -83.750  -15.833 1.00 18.73  ? 359  ARG C CA    1 
ATOM   9392  C C     . ARG C 1 359 ? -44.817  -83.858  -17.327 1.00 21.51  ? 359  ARG C C     1 
ATOM   9393  O O     . ARG C 1 359 ? -45.357  -84.750  -17.982 1.00 25.21  ? 359  ARG C O     1 
ATOM   9394  C CB    . ARG C 1 359 ? -44.477  -84.944  -15.076 1.00 18.90  ? 359  ARG C CB    1 
ATOM   9395  C CG    . ARG C 1 359 ? -44.691  -84.916  -13.569 1.00 19.37  ? 359  ARG C CG    1 
ATOM   9396  C CD    . ARG C 1 359 ? -43.990  -83.677  -12.906 1.00 21.45  ? 359  ARG C CD    1 
ATOM   9397  N NE    . ARG C 1 359 ? -44.095  -83.727  -11.436 1.00 23.51  ? 359  ARG C NE    1 
ATOM   9398  C CZ    . ARG C 1 359 ? -43.281  -84.453  -10.636 1.00 23.26  ? 359  ARG C CZ    1 
ATOM   9399  N NH1   . ARG C 1 359 ? -42.168  -85.004  -11.138 1.00 18.53  ? 359  ARG C NH1   1 
ATOM   9400  N NH2   . ARG C 1 359 ? -43.583  -84.580  -9.347  1.00 20.32  ? 359  ARG C NH2   1 
ATOM   9401  N N     . SER C 1 360 ? -43.971  -82.966  -17.850 1.00 19.94  ? 360  SER C N     1 
ATOM   9402  C CA    . SER C 1 360 ? -43.734  -82.870  -19.278 1.00 21.78  ? 360  SER C CA    1 
ATOM   9403  C C     . SER C 1 360 ? -42.305  -83.258  -19.657 1.00 23.36  ? 360  SER C C     1 
ATOM   9404  O O     . SER C 1 360 ? -41.367  -83.170  -18.841 1.00 20.05  ? 360  SER C O     1 
ATOM   9405  C CB    . SER C 1 360 ? -44.057  -81.488  -19.793 1.00 21.20  ? 360  SER C CB    1 
ATOM   9406  O OG    . SER C 1 360 ? -45.446  -81.248  -19.613 1.00 24.32  ? 360  SER C OG    1 
ATOM   9407  N N     . PHE C 1 361 ? -42.183  -83.672  -20.932 1.00 20.58  ? 361  PHE C N     1 
ATOM   9408  C CA    . PHE C 1 361 ? -40.937  -84.101  -21.539 1.00 21.33  ? 361  PHE C CA    1 
ATOM   9409  C C     . PHE C 1 361 ? -40.939  -83.556  -22.963 1.00 21.80  ? 361  PHE C C     1 
ATOM   9410  O O     . PHE C 1 361 ? -41.992  -83.444  -23.571 1.00 24.04  ? 361  PHE C O     1 
ATOM   9411  C CB    . PHE C 1 361 ? -40.960  -85.632  -21.558 1.00 18.50  ? 361  PHE C CB    1 
ATOM   9412  C CG    . PHE C 1 361 ? -41.066  -86.192  -20.150 1.00 21.55  ? 361  PHE C CG    1 
ATOM   9413  C CD1   . PHE C 1 361 ? -39.909  -86.433  -19.390 1.00 22.99  ? 361  PHE C CD1   1 
ATOM   9414  C CD2   . PHE C 1 361 ? -42.321  -86.417  -19.557 1.00 22.02  ? 361  PHE C CD2   1 
ATOM   9415  C CE1   . PHE C 1 361 ? -40.012  -86.931  -18.094 1.00 21.59  ? 361  PHE C CE1   1 
ATOM   9416  C CE2   . PHE C 1 361 ? -42.421  -86.887  -18.247 1.00 23.49  ? 361  PHE C CE2   1 
ATOM   9417  C CZ    . PHE C 1 361 ? -41.272  -87.126  -17.514 1.00 20.60  ? 361  PHE C CZ    1 
ATOM   9418  N N     . VAL C 1 362 ? -39.752  -83.262  -23.481 1.00 20.25  ? 362  VAL C N     1 
ATOM   9419  C CA    . VAL C 1 362 ? -39.541  -82.744  -24.821 1.00 22.09  ? 362  VAL C CA    1 
ATOM   9420  C C     . VAL C 1 362 ? -38.592  -83.685  -25.546 1.00 23.60  ? 362  VAL C C     1 
ATOM   9421  O O     . VAL C 1 362 ? -37.504  -83.986  -25.046 1.00 21.52  ? 362  VAL C O     1 
ATOM   9422  C CB    . VAL C 1 362 ? -38.847  -81.370  -24.697 1.00 26.84  ? 362  VAL C CB    1 
ATOM   9423  C CG1   . VAL C 1 362 ? -38.424  -80.821  -26.067 1.00 23.50  ? 362  VAL C CG1   1 
ATOM   9424  C CG2   . VAL C 1 362 ? -39.690  -80.388  -23.866 1.00 18.93  ? 362  VAL C CG2   1 
ATOM   9425  N N     . GLY C 1 363 ? -39.013  -84.166  -26.719 1.00 26.04  ? 363  GLY C N     1 
ATOM   9426  C CA    . GLY C 1 363 ? -38.180  -85.057  -27.508 1.00 25.37  ? 363  GLY C CA    1 
ATOM   9427  C C     . GLY C 1 363 ? -38.894  -86.361  -27.884 1.00 31.07  ? 363  GLY C C     1 
ATOM   9428  O O     . GLY C 1 363 ? -38.323  -87.191  -28.567 1.00 35.80  ? 363  GLY C O     1 
ATOM   9429  N N     . ILE C 1 364 ? -40.160  -86.530  -27.498 1.00 33.15  ? 364  ILE C N     1 
ATOM   9430  C CA    . ILE C 1 364 ? -40.922  -87.694  -27.921 1.00 33.82  ? 364  ILE C CA    1 
ATOM   9431  C C     . ILE C 1 364 ? -41.809  -87.332  -29.105 1.00 34.27  ? 364  ILE C C     1 
ATOM   9432  O O     . ILE C 1 364 ? -42.719  -86.532  -28.965 1.00 32.89  ? 364  ILE C O     1 
ATOM   9433  C CB    . ILE C 1 364 ? -41.687  -88.272  -26.722 1.00 34.29  ? 364  ILE C CB    1 
ATOM   9434  C CG1   . ILE C 1 364 ? -40.659  -88.926  -25.787 1.00 30.31  ? 364  ILE C CG1   1 
ATOM   9435  C CG2   . ILE C 1 364 ? -42.745  -89.276  -27.187 1.00 26.41  ? 364  ILE C CG2   1 
ATOM   9436  C CD1   . ILE C 1 364 ? -41.228  -89.459  -24.520 1.00 32.74  ? 364  ILE C CD1   1 
ATOM   9437  N N     . GLY C 1 365 ? -41.506  -87.910  -30.277 1.00 34.77  ? 365  GLY C N     1 
ATOM   9438  C CA    . GLY C 1 365 ? -42.110  -87.510  -31.542 1.00 33.52  ? 365  GLY C CA    1 
ATOM   9439  C C     . GLY C 1 365 ? -43.140  -88.508  -32.095 1.00 37.22  ? 365  GLY C C     1 
ATOM   9440  O O     . GLY C 1 365 ? -43.814  -88.217  -33.078 1.00 39.29  ? 365  GLY C O     1 
ATOM   9441  N N     . GLN C 1 366 ? -43.292  -89.677  -31.456 1.00 35.74  ? 366  GLN C N     1 
ATOM   9442  C CA    . GLN C 1 366 ? -44.122  -90.754  -31.976 1.00 34.50  ? 366  GLN C CA    1 
ATOM   9443  C C     . GLN C 1 366 ? -45.428  -90.815  -31.180 1.00 37.35  ? 366  GLN C C     1 
ATOM   9444  O O     . GLN C 1 366 ? -45.426  -90.633  -29.956 1.00 34.43  ? 366  GLN C O     1 
ATOM   9445  C CB    . GLN C 1 366 ? -43.379  -92.093  -31.887 1.00 30.59  ? 366  GLN C CB    1 
ATOM   9446  C CG    . GLN C 1 366 ? -42.168  -92.206  -32.815 1.00 41.00  ? 366  GLN C CG    1 
ATOM   9447  C CD    . GLN C 1 366 ? -42.449  -91.749  -34.245 1.00 57.89  ? 366  GLN C CD    1 
ATOM   9448  O OE1   . GLN C 1 366 ? -43.393  -92.182  -34.923 1.00 60.47  ? 366  GLN C OE1   1 
ATOM   9449  N NE2   . GLN C 1 366 ? -41.663  -90.797  -34.721 1.00 56.13  ? 366  GLN C NE2   1 
ATOM   9450  N N     . PRO C 1 367 ? -46.584  -91.098  -31.822 1.00 34.00  ? 367  PRO C N     1 
ATOM   9451  C CA    . PRO C 1 367 ? -47.835  -91.239  -31.075 1.00 31.95  ? 367  PRO C CA    1 
ATOM   9452  C C     . PRO C 1 367 ? -47.811  -92.406  -30.084 1.00 30.29  ? 367  PRO C C     1 
ATOM   9453  O O     . PRO C 1 367 ? -47.259  -93.467  -30.392 1.00 28.49  ? 367  PRO C O     1 
ATOM   9454  C CB    . PRO C 1 367 ? -48.926  -91.478  -32.135 1.00 28.95  ? 367  PRO C CB    1 
ATOM   9455  C CG    . PRO C 1 367 ? -48.170  -91.645  -33.447 1.00 29.55  ? 367  PRO C CG    1 
ATOM   9456  C CD    . PRO C 1 367 ? -46.727  -91.255  -33.280 1.00 29.18  ? 367  PRO C CD    1 
ATOM   9457  N N     . ILE C 1 368 ? -48.443  -92.210  -28.917 1.00 25.84  ? 368  ILE C N     1 
ATOM   9458  C CA    . ILE C 1 368 ? -48.349  -93.181  -27.850 1.00 26.93  ? 368  ILE C CA    1 
ATOM   9459  C C     . ILE C 1 368 ? -49.689  -93.895  -27.735 1.00 29.17  ? 368  ILE C C     1 
ATOM   9460  O O     . ILE C 1 368 ? -50.737  -93.269  -27.808 1.00 28.60  ? 368  ILE C O     1 
ATOM   9461  C CB    . ILE C 1 368 ? -47.909  -92.502  -26.529 1.00 24.93  ? 368  ILE C CB    1 
ATOM   9462  C CG1   . ILE C 1 368 ? -46.414  -92.177  -26.536 1.00 25.25  ? 368  ILE C CG1   1 
ATOM   9463  C CG2   . ILE C 1 368 ? -48.301  -93.340  -25.291 1.00 21.30  ? 368  ILE C CG2   1 
ATOM   9464  C CD1   . ILE C 1 368 ? -45.998  -91.154  -25.473 1.00 27.84  ? 368  ILE C CD1   1 
ATOM   9465  N N     . GLN C 1 369 ? -49.650  -95.201  -27.469 1.00 29.78  ? 369  GLN C N     1 
ATOM   9466  C CA    . GLN C 1 369 ? -50.887  -95.915  -27.237 1.00 30.53  ? 369  GLN C CA    1 
ATOM   9467  C C     . GLN C 1 369 ? -51.257  -95.938  -25.751 1.00 30.39  ? 369  GLN C C     1 
ATOM   9468  O O     . GLN C 1 369 ? -52.415  -95.740  -25.410 1.00 29.82  ? 369  GLN C O     1 
ATOM   9469  C CB    . GLN C 1 369 ? -50.763  -97.329  -27.795 1.00 35.82  ? 369  GLN C CB    1 
ATOM   9470  C CG    . GLN C 1 369 ? -52.083  -98.093  -27.783 1.00 51.90  ? 369  GLN C CG    1 
ATOM   9471  C CD    . GLN C 1 369 ? -51.863  -99.568  -27.520 1.00 73.92  ? 369  GLN C CD    1 
ATOM   9472  O OE1   . GLN C 1 369 ? -51.124  -100.227 -28.265 1.00 80.38  ? 369  GLN C OE1   1 
ATOM   9473  N NE2   . GLN C 1 369 ? -52.422  -100.054 -26.411 1.00 85.75  ? 369  GLN C NE2   1 
ATOM   9474  N N     . ARG C 1 370 ? -50.300  -96.223  -24.866 1.00 31.67  ? 370  ARG C N     1 
ATOM   9475  C CA    . ARG C 1 370 ? -50.629  -96.378  -23.451 1.00 31.42  ? 370  ARG C CA    1 
ATOM   9476  C C     . ARG C 1 370 ? -49.389  -96.077  -22.601 1.00 29.08  ? 370  ARG C C     1 
ATOM   9477  O O     . ARG C 1 370 ? -48.250  -96.333  -23.018 1.00 29.41  ? 370  ARG C O     1 
ATOM   9478  C CB    . ARG C 1 370 ? -51.014  -97.846  -23.272 1.00 36.09  ? 370  ARG C CB    1 
ATOM   9479  C CG    . ARG C 1 370 ? -52.003  -98.204  -22.178 1.00 51.86  ? 370  ARG C CG    1 
ATOM   9480  C CD    . ARG C 1 370 ? -52.503  -99.640  -22.401 1.00 69.83  ? 370  ARG C CD    1 
ATOM   9481  N NE    . ARG C 1 370 ? -51.727  -100.537 -21.531 1.00 87.44  ? 370  ARG C NE    1 
ATOM   9482  C CZ    . ARG C 1 370 ? -52.144  -101.135 -20.406 1.00 95.19  ? 370  ARG C CZ    1 
ATOM   9483  N NH1   . ARG C 1 370 ? -53.425  -101.103 -20.066 1.00 93.90  ? 370  ARG C NH1   1 
ATOM   9484  N NH2   . ARG C 1 370 ? -51.279  -101.780 -19.632 1.00 88.36  ? 370  ARG C NH2   1 
ATOM   9485  N N     . ILE C 1 371 ? -49.618  -95.549  -21.396 1.00 25.89  ? 371  ILE C N     1 
ATOM   9486  C CA    . ILE C 1 371 ? -48.562  -95.364  -20.409 1.00 24.31  ? 371  ILE C CA    1 
ATOM   9487  C C     . ILE C 1 371 ? -49.052  -95.965  -19.093 1.00 25.10  ? 371  ILE C C     1 
ATOM   9488  O O     . ILE C 1 371 ? -50.176  -95.674  -18.685 1.00 25.52  ? 371  ILE C O     1 
ATOM   9489  C CB    . ILE C 1 371 ? -48.251  -93.861  -20.245 1.00 22.42  ? 371  ILE C CB    1 
ATOM   9490  C CG1   . ILE C 1 371 ? -47.991  -93.187  -21.612 1.00 19.04  ? 371  ILE C CG1   1 
ATOM   9491  C CG2   . ILE C 1 371 ? -47.080  -93.674  -19.280 1.00 21.50  ? 371  ILE C CG2   1 
ATOM   9492  C CD1   . ILE C 1 371 ? -47.584  -91.724  -21.540 1.00 17.15  ? 371  ILE C CD1   1 
ATOM   9493  N N     . HIS C 1 372 ? -48.194  -96.722  -18.395 1.00 23.77  ? 372  HIS C N     1 
ATOM   9494  C CA    . HIS C 1 372 ? -48.606  -97.278  -17.114 1.00 23.97  ? 372  HIS C CA    1 
ATOM   9495  C C     . HIS C 1 372 ? -47.424  -97.352  -16.135 1.00 23.43  ? 372  HIS C C     1 
ATOM   9496  O O     . HIS C 1 372 ? -46.279  -97.606  -16.533 1.00 22.61  ? 372  HIS C O     1 
ATOM   9497  C CB    . HIS C 1 372 ? -49.298  -98.632  -17.306 1.00 23.68  ? 372  HIS C CB    1 
ATOM   9498  C CG    . HIS C 1 372 ? -48.392  -99.713  -17.793 1.00 30.50  ? 372  HIS C CG    1 
ATOM   9499  N ND1   . HIS C 1 372 ? -48.120  -99.948  -19.141 1.00 33.37  ? 372  HIS C ND1   1 
ATOM   9500  C CD2   . HIS C 1 372 ? -47.668  -100.627 -17.078 1.00 29.19  ? 372  HIS C CD2   1 
ATOM   9501  C CE1   . HIS C 1 372 ? -47.283  -100.983 -19.234 1.00 28.93  ? 372  HIS C CE1   1 
ATOM   9502  N NE2   . HIS C 1 372 ? -47.006  -101.404 -17.993 1.00 30.71  ? 372  HIS C NE2   1 
ATOM   9503  N N     . TRP C 1 373 ? -47.721  -97.141  -14.848 1.00 17.67  ? 373  TRP C N     1 
ATOM   9504  C CA    . TRP C 1 373 ? -46.749  -97.321  -13.783 1.00 18.11  ? 373  TRP C CA    1 
ATOM   9505  C C     . TRP C 1 373 ? -46.354  -98.796  -13.679 1.00 20.53  ? 373  TRP C C     1 
ATOM   9506  O O     . TRP C 1 373 ? -47.219  -99.666  -13.626 1.00 25.83  ? 373  TRP C O     1 
ATOM   9507  C CB    . TRP C 1 373 ? -47.366  -96.894  -12.449 1.00 15.41  ? 373  TRP C CB    1 
ATOM   9508  C CG    . TRP C 1 373 ? -47.586  -95.408  -12.255 1.00 17.57  ? 373  TRP C CG    1 
ATOM   9509  C CD1   . TRP C 1 373 ? -48.746  -94.838  -11.811 1.00 17.45  ? 373  TRP C CD1   1 
ATOM   9510  C CD2   . TRP C 1 373 ? -46.628  -94.327  -12.382 1.00 16.02  ? 373  TRP C CD2   1 
ATOM   9511  N NE1   . TRP C 1 373 ? -48.597  -93.486  -11.703 1.00 17.61  ? 373  TRP C NE1   1 
ATOM   9512  C CE2   . TRP C 1 373 ? -47.314  -93.138  -12.029 1.00 17.23  ? 373  TRP C CE2   1 
ATOM   9513  C CE3   . TRP C 1 373 ? -45.275  -94.244  -12.757 1.00 14.53  ? 373  TRP C CE3   1 
ATOM   9514  C CZ2   . TRP C 1 373 ? -46.691  -91.872  -12.029 1.00 17.98  ? 373  TRP C CZ2   1 
ATOM   9515  C CZ3   . TRP C 1 373 ? -44.658  -93.003  -12.759 1.00 16.38  ? 373  TRP C CZ3   1 
ATOM   9516  C CH2   . TRP C 1 373 ? -45.355  -91.819  -12.390 1.00 16.29  ? 373  TRP C CH2   1 
ATOM   9517  N N     . LEU C 1 374 ? -45.044  -99.084  -13.591 1.00 24.83  ? 374  LEU C N     1 
ATOM   9518  C CA    . LEU C 1 374 ? -44.543  -100.438 -13.398 1.00 20.16  ? 374  LEU C CA    1 
ATOM   9519  C C     . LEU C 1 374 ? -44.968  -100.999 -12.050 1.00 20.71  ? 374  LEU C C     1 
ATOM   9520  O O     . LEU C 1 374 ? -45.119  -102.191 -11.945 1.00 24.44  ? 374  LEU C O     1 
ATOM   9521  C CB    . LEU C 1 374 ? -43.027  -100.496 -13.512 1.00 21.92  ? 374  LEU C CB    1 
ATOM   9522  C CG    . LEU C 1 374 ? -42.455  -100.234 -14.903 1.00 21.59  ? 374  LEU C CG    1 
ATOM   9523  C CD1   . LEU C 1 374 ? -40.953  -100.489 -14.825 1.00 20.64  ? 374  LEU C CD1   1 
ATOM   9524  C CD2   . LEU C 1 374 ? -43.111  -101.150 -15.923 1.00 19.16  ? 374  LEU C CD2   1 
ATOM   9525  N N     . ASP C 1 375 ? -45.117  -100.190 -10.997 1.00 20.49  ? 375  ASP C N     1 
ATOM   9526  C CA    . ASP C 1 375 ? -45.354  -100.763 -9.682  1.00 18.79  ? 375  ASP C CA    1 
ATOM   9527  C C     . ASP C 1 375 ? -46.772  -101.331 -9.547  1.00 21.99  ? 375  ASP C C     1 
ATOM   9528  O O     . ASP C 1 375 ? -46.966  -102.239 -8.752  1.00 25.91  ? 375  ASP C O     1 
ATOM   9529  C CB    . ASP C 1 375 ? -45.116  -99.757  -8.570  1.00 19.28  ? 375  ASP C CB    1 
ATOM   9530  C CG    . ASP C 1 375 ? -45.870  -98.447  -8.757  1.00 23.27  ? 375  ASP C CG    1 
ATOM   9531  O OD1   . ASP C 1 375 ? -45.417  -97.640  -9.619  1.00 22.66  ? 375  ASP C OD1   1 
ATOM   9532  O OD2   . ASP C 1 375 ? -46.946  -98.277  -8.092  1.00 22.97  ? 375  ASP C OD2   1 
ATOM   9533  N N     . ASN C 1 376 ? -47.783  -100.794 -10.247 1.00 19.83  ? 376  ASN C N     1 
ATOM   9534  C CA    . ASN C 1 376 ? -49.141  -101.247 -9.974  1.00 21.98  ? 376  ASN C CA    1 
ATOM   9535  C C     . ASN C 1 376 ? -49.969  -101.314 -11.258 1.00 23.79  ? 376  ASN C C     1 
ATOM   9536  O O     . ASN C 1 376 ? -51.157  -101.560 -11.183 1.00 30.31  ? 376  ASN C O     1 
ATOM   9537  C CB    . ASN C 1 376 ? -49.856  -100.403 -8.905  1.00 18.56  ? 376  ASN C CB    1 
ATOM   9538  C CG    . ASN C 1 376 ? -50.174  -99.004  -9.411  1.00 21.07  ? 376  ASN C CG    1 
ATOM   9539  O OD1   . ASN C 1 376 ? -49.740  -98.590  -10.503 1.00 20.60  ? 376  ASN C OD1   1 
ATOM   9540  N ND2   . ASN C 1 376 ? -50.912  -98.215  -8.649  1.00 21.53  ? 376  ASN C ND2   1 
ATOM   9541  N N     . ASP C 1 377 ? -49.378  -101.025 -12.419 1.00 26.28  ? 377  ASP C N     1 
ATOM   9542  C CA    . ASP C 1 377 ? -50.074  -101.117 -13.702 1.00 30.74  ? 377  ASP C CA    1 
ATOM   9543  C C     . ASP C 1 377 ? -51.166  -100.064 -13.894 1.00 27.79  ? 377  ASP C C     1 
ATOM   9544  O O     . ASP C 1 377 ? -51.912  -100.166 -14.843 1.00 27.32  ? 377  ASP C O     1 
ATOM   9545  C CB    . ASP C 1 377 ? -50.578  -102.520 -14.016 1.00 38.03  ? 377  ASP C CB    1 
ATOM   9546  C CG    . ASP C 1 377 ? -49.465  -103.551 -14.221 1.00 51.73  ? 377  ASP C CG    1 
ATOM   9547  O OD1   . ASP C 1 377 ? -48.468  -103.249 -14.913 1.00 58.98  ? 377  ASP C OD1   1 
ATOM   9548  O OD2   . ASP C 1 377 ? -49.566  -104.651 -13.659 1.00 56.48  ? 377  ASP C OD2   1 
ATOM   9549  N N     . GLU C 1 378 ? -51.266  -99.045  -13.045 1.00 24.77  ? 378  GLU C N     1 
ATOM   9550  C CA    . GLU C 1 378 ? -52.226  -97.982  -13.313 1.00 25.64  ? 378  GLU C CA    1 
ATOM   9551  C C     . GLU C 1 378 ? -51.891  -97.285  -14.631 1.00 24.63  ? 378  GLU C C     1 
ATOM   9552  O O     . GLU C 1 378 ? -50.733  -96.977  -14.906 1.00 24.10  ? 378  GLU C O     1 
ATOM   9553  C CB    . GLU C 1 378 ? -52.234  -96.992  -12.152 1.00 25.19  ? 378  GLU C CB    1 
ATOM   9554  C CG    . GLU C 1 378 ? -53.261  -95.885  -12.335 1.00 29.87  ? 378  GLU C CG    1 
ATOM   9555  C CD    . GLU C 1 378 ? -53.016  -94.688  -11.421 1.00 38.18  ? 378  GLU C CD    1 
ATOM   9556  O OE1   . GLU C 1 378 ? -52.045  -94.689  -10.630 1.00 42.80  ? 378  GLU C OE1   1 
ATOM   9557  O OE2   . GLU C 1 378 ? -53.829  -93.750  -11.489 1.00 45.38  ? 378  GLU C OE2   1 
ATOM   9558  N N     . VAL C 1 379 ? -52.929  -97.067  -15.454 1.00 25.02  ? 379  VAL C N     1 
ATOM   9559  C CA    . VAL C 1 379 ? -52.812  -96.384  -16.729 1.00 25.25  ? 379  VAL C CA    1 
ATOM   9560  C C     . VAL C 1 379 ? -52.838  -94.877  -16.488 1.00 27.78  ? 379  VAL C C     1 
ATOM   9561  O O     . VAL C 1 379 ? -53.687  -94.394  -15.747 1.00 26.62  ? 379  VAL C O     1 
ATOM   9562  C CB    . VAL C 1 379 ? -54.007  -96.819  -17.604 1.00 26.99  ? 379  VAL C CB    1 
ATOM   9563  C CG1   . VAL C 1 379 ? -54.108  -95.983  -18.880 1.00 22.15  ? 379  VAL C CG1   1 
ATOM   9564  C CG2   . VAL C 1 379 ? -53.898  -98.292  -17.975 1.00 25.85  ? 379  VAL C CG2   1 
ATOM   9565  N N     . LEU C 1 380 ? -51.925  -94.141  -17.143 1.00 25.75  ? 380  LEU C N     1 
ATOM   9566  C CA    . LEU C 1 380 ? -51.807  -92.703  -16.942 1.00 24.00  ? 380  LEU C CA    1 
ATOM   9567  C C     . LEU C 1 380 ? -52.508  -91.967  -18.074 1.00 22.92  ? 380  LEU C C     1 
ATOM   9568  O O     . LEU C 1 380 ? -52.414  -92.375  -19.222 1.00 22.58  ? 380  LEU C O     1 
ATOM   9569  C CB    . LEU C 1 380 ? -50.337  -92.282  -16.871 1.00 22.72  ? 380  LEU C CB    1 
ATOM   9570  C CG    . LEU C 1 380 ? -49.444  -92.986  -15.843 1.00 25.20  ? 380  LEU C CG    1 
ATOM   9571  C CD1   . LEU C 1 380 ? -48.188  -92.164  -15.607 1.00 27.39  ? 380  LEU C CD1   1 
ATOM   9572  C CD2   . LEU C 1 380 ? -50.250  -93.016  -14.556 1.00 29.79  ? 380  LEU C CD2   1 
ATOM   9573  N N     . SER C 1 381 ? -53.145  -90.837  -17.782 1.00 20.69  ? 381  SER C N     1 
ATOM   9574  C CA    . SER C 1 381 ? -53.590  -90.025  -18.899 1.00 22.77  ? 381  SER C CA    1 
ATOM   9575  C C     . SER C 1 381 ? -52.440  -89.136  -19.377 1.00 25.23  ? 381  SER C C     1 
ATOM   9576  O O     . SER C 1 381 ? -51.520  -88.820  -18.622 1.00 23.05  ? 381  SER C O     1 
ATOM   9577  C CB    . SER C 1 381 ? -54.824  -89.252  -18.527 1.00 25.40  ? 381  SER C CB    1 
ATOM   9578  O OG    . SER C 1 381 ? -54.573  -88.430  -17.402 1.00 27.34  ? 381  SER C OG    1 
ATOM   9579  N N     . PHE C 1 382 ? -52.480  -88.738  -20.654 1.00 26.05  ? 382  PHE C N     1 
ATOM   9580  C CA    . PHE C 1 382 ? -51.412  -87.966  -21.259 1.00 25.48  ? 382  PHE C CA    1 
ATOM   9581  C C     . PHE C 1 382 ? -51.961  -87.173  -22.452 1.00 28.99  ? 382  PHE C C     1 
ATOM   9582  O O     . PHE C 1 382 ? -53.033  -87.481  -22.958 1.00 30.41  ? 382  PHE C O     1 
ATOM   9583  C CB    . PHE C 1 382 ? -50.300  -88.942  -21.668 1.00 23.53  ? 382  PHE C CB    1 
ATOM   9584  C CG    . PHE C 1 382 ? -50.658  -89.863  -22.829 1.00 21.93  ? 382  PHE C CG    1 
ATOM   9585  C CD1   . PHE C 1 382 ? -50.462  -89.462  -24.149 1.00 20.63  ? 382  PHE C CD1   1 
ATOM   9586  C CD2   . PHE C 1 382 ? -51.257  -91.104  -22.589 1.00 22.33  ? 382  PHE C CD2   1 
ATOM   9587  C CE1   . PHE C 1 382 ? -50.843  -90.286  -25.214 1.00 22.86  ? 382  PHE C CE1   1 
ATOM   9588  C CE2   . PHE C 1 382 ? -51.624  -91.934  -23.646 1.00 23.14  ? 382  PHE C CE2   1 
ATOM   9589  C CZ    . PHE C 1 382 ? -51.423  -91.523  -24.963 1.00 22.67  ? 382  PHE C CZ    1 
ATOM   9590  N N     . THR C 1 383 ? -51.219  -86.148  -22.894 1.00 27.22  ? 383  THR C N     1 
ATOM   9591  C CA    . THR C 1 383 ? -51.485  -85.416  -24.126 1.00 28.80  ? 383  THR C CA    1 
ATOM   9592  C C     . THR C 1 383 ? -50.139  -85.290  -24.837 1.00 23.59  ? 383  THR C C     1 
ATOM   9593  O O     . THR C 1 383 ? -49.080  -85.290  -24.195 1.00 24.80  ? 383  THR C O     1 
ATOM   9594  C CB    . THR C 1 383 ? -52.061  -84.006  -23.857 1.00 31.96  ? 383  THR C CB    1 
ATOM   9595  O OG1   . THR C 1 383 ? -51.089  -83.289  -23.092 1.00 37.50  ? 383  THR C OG1   1 
ATOM   9596  C CG2   . THR C 1 383 ? -53.317  -83.978  -23.013 1.00 24.21  ? 383  THR C CG2   1 
ATOM   9597  N N     . GLN C 1 384 ? -50.183  -85.139  -26.162 1.00 21.79  ? 384  GLN C N     1 
ATOM   9598  C CA    . GLN C 1 384 ? -48.979  -84.972  -26.955 1.00 23.04  ? 384  GLN C CA    1 
ATOM   9599  C C     . GLN C 1 384 ? -49.140  -83.794  -27.891 1.00 24.50  ? 384  GLN C C     1 
ATOM   9600  O O     . GLN C 1 384 ? -50.228  -83.522  -28.348 1.00 26.97  ? 384  GLN C O     1 
ATOM   9601  C CB    . GLN C 1 384 ? -48.685  -86.190  -27.820 1.00 21.44  ? 384  GLN C CB    1 
ATOM   9602  C CG    . GLN C 1 384 ? -48.420  -87.443  -27.005 1.00 24.19  ? 384  GLN C CG    1 
ATOM   9603  C CD    . GLN C 1 384 ? -47.941  -88.616  -27.828 1.00 26.47  ? 384  GLN C CD    1 
ATOM   9604  O OE1   . GLN C 1 384 ? -48.732  -89.469  -28.237 1.00 27.80  ? 384  GLN C OE1   1 
ATOM   9605  N NE2   . GLN C 1 384 ? -46.645  -88.665  -28.101 1.00 26.11  ? 384  GLN C NE2   1 
ATOM   9606  N N     . ASP C 1 385 ? -48.035  -83.108  -28.169 1.00 27.78  ? 385  ASP C N     1 
ATOM   9607  C CA    . ASP C 1 385 ? -47.909  -82.229  -29.321 1.00 29.21  ? 385  ASP C CA    1 
ATOM   9608  C C     . ASP C 1 385 ? -46.765  -82.803  -30.155 1.00 28.82  ? 385  ASP C C     1 
ATOM   9609  O O     . ASP C 1 385 ? -45.579  -82.627  -29.813 1.00 30.70  ? 385  ASP C O     1 
ATOM   9610  C CB    . ASP C 1 385 ? -47.656  -80.781  -28.905 1.00 28.55  ? 385  ASP C CB    1 
ATOM   9611  C CG    . ASP C 1 385 ? -47.319  -79.818  -30.042 1.00 34.65  ? 385  ASP C CG    1 
ATOM   9612  O OD1   . ASP C 1 385 ? -46.980  -80.298  -31.159 1.00 37.33  ? 385  ASP C OD1   1 
ATOM   9613  O OD2   . ASP C 1 385 ? -47.402  -78.587  -29.812 1.00 44.57  ? 385  ASP C OD2   1 
ATOM   9614  N N     . LEU C 1 386 ? -47.137  -83.502  -31.240 1.00 29.05  ? 386  LEU C N     1 
ATOM   9615  C CA    . LEU C 1 386 ? -46.156  -84.253  -32.007 1.00 29.01  ? 386  LEU C CA    1 
ATOM   9616  C C     . LEU C 1 386 ? -45.215  -83.311  -32.754 1.00 27.93  ? 386  LEU C C     1 
ATOM   9617  O O     . LEU C 1 386 ? -44.042  -83.649  -32.900 1.00 31.26  ? 386  LEU C O     1 
ATOM   9618  C CB    . LEU C 1 386 ? -46.801  -85.296  -32.910 1.00 28.48  ? 386  LEU C CB    1 
ATOM   9619  C CG    . LEU C 1 386 ? -47.649  -86.338  -32.181 1.00 33.97  ? 386  LEU C CG    1 
ATOM   9620  C CD1   . LEU C 1 386 ? -48.522  -87.133  -33.151 1.00 30.69  ? 386  LEU C CD1   1 
ATOM   9621  C CD2   . LEU C 1 386 ? -46.758  -87.253  -31.325 1.00 28.34  ? 386  LEU C CD2   1 
ATOM   9622  N N     . ASP C 1 387 ? -45.683  -82.117  -33.166 1.00 29.31  ? 387  ASP C N     1 
ATOM   9623  C CA    . ASP C 1 387 ? -44.778  -81.217  -33.874 1.00 36.47  ? 387  ASP C CA    1 
ATOM   9624  C C     . ASP C 1 387 ? -43.642  -80.726  -32.987 1.00 35.70  ? 387  ASP C C     1 
ATOM   9625  O O     . ASP C 1 387 ? -42.512  -80.640  -33.451 1.00 32.16  ? 387  ASP C O     1 
ATOM   9626  C CB    . ASP C 1 387 ? -45.504  -80.070  -34.561 1.00 46.58  ? 387  ASP C CB    1 
ATOM   9627  C CG    . ASP C 1 387 ? -46.472  -80.567  -35.624 1.00 62.08  ? 387  ASP C CG    1 
ATOM   9628  O OD1   . ASP C 1 387 ? -46.039  -81.363  -36.488 1.00 67.82  ? 387  ASP C OD1   1 
ATOM   9629  O OD2   . ASP C 1 387 ? -47.656  -80.199  -35.561 1.00 69.90  ? 387  ASP C OD2   1 
ATOM   9630  N N     . LYS C 1 388 ? -43.957  -80.406  -31.721 1.00 31.04  ? 388  LYS C N     1 
ATOM   9631  C CA    . LYS C 1 388 ? -42.951  -79.851  -30.837 1.00 30.11  ? 388  LYS C CA    1 
ATOM   9632  C C     . LYS C 1 388 ? -42.309  -80.958  -30.008 1.00 31.67  ? 388  LYS C C     1 
ATOM   9633  O O     . LYS C 1 388 ? -41.354  -80.699  -29.272 1.00 32.11  ? 388  LYS C O     1 
ATOM   9634  C CB    . LYS C 1 388 ? -43.573  -78.659  -30.098 1.00 26.33  ? 388  LYS C CB    1 
ATOM   9635  C CG    . LYS C 1 388 ? -43.355  -77.419  -30.957 1.00 25.65  ? 388  LYS C CG    1 
ATOM   9636  C CD    . LYS C 1 388 ? -44.054  -76.219  -30.334 1.00 26.67  ? 388  LYS C CD    1 
ATOM   9637  C CE    . LYS C 1 388 ? -43.713  -74.965  -31.085 1.00 27.61  ? 388  LYS C CE    1 
ATOM   9638  N NZ    . LYS C 1 388 ? -44.257  -73.871  -30.269 1.00 25.75  ? 388  LYS C NZ    1 
ATOM   9639  N N     . LYS C 1 389 ? -42.853  -82.171  -30.131 1.00 26.29  ? 389  LYS C N     1 
ATOM   9640  C CA    . LYS C 1 389 ? -42.309  -83.335  -29.455 1.00 29.74  ? 389  LYS C CA    1 
ATOM   9641  C C     . LYS C 1 389 ? -42.510  -83.223  -27.946 1.00 25.09  ? 389  LYS C C     1 
ATOM   9642  O O     . LYS C 1 389 ? -41.631  -83.598  -27.177 1.00 27.15  ? 389  LYS C O     1 
ATOM   9643  C CB    . LYS C 1 389 ? -40.879  -83.655  -29.902 1.00 29.69  ? 389  LYS C CB    1 
ATOM   9644  C CG    . LYS C 1 389 ? -40.632  -83.815  -31.390 1.00 38.70  ? 389  LYS C CG    1 
ATOM   9645  C CD    . LYS C 1 389 ? -39.189  -84.322  -31.496 1.00 49.52  ? 389  LYS C CD    1 
ATOM   9646  C CE    . LYS C 1 389 ? -38.416  -84.279  -32.774 1.00 55.82  ? 389  LYS C CE    1 
ATOM   9647  N NZ    . LYS C 1 389 ? -39.024  -85.192  -33.737 1.00 75.26  ? 389  LYS C NZ    1 
ATOM   9648  N N     . VAL C 1 390 ? -43.700  -82.762  -27.542 1.00 21.13  ? 390  VAL C N     1 
ATOM   9649  C CA    . VAL C 1 390 ? -44.021  -82.595  -26.140 1.00 20.33  ? 390  VAL C CA    1 
ATOM   9650  C C     . VAL C 1 390 ? -44.954  -83.723  -25.702 1.00 23.33  ? 390  VAL C C     1 
ATOM   9651  O O     . VAL C 1 390 ? -45.953  -84.003  -26.377 1.00 22.99  ? 390  VAL C O     1 
ATOM   9652  C CB    . VAL C 1 390 ? -44.644  -81.229  -25.827 1.00 20.76  ? 390  VAL C CB    1 
ATOM   9653  C CG1   . VAL C 1 390 ? -45.023  -81.123  -24.353 1.00 19.78  ? 390  VAL C CG1   1 
ATOM   9654  C CG2   . VAL C 1 390 ? -43.728  -80.077  -26.242 1.00 19.73  ? 390  VAL C CG2   1 
ATOM   9655  N N     . LEU C 1 391 ? -44.599  -84.361  -24.567 1.00 21.83  ? 391  LEU C N     1 
ATOM   9656  C CA    . LEU C 1 391 ? -45.475  -85.283  -23.864 1.00 19.71  ? 391  LEU C CA    1 
ATOM   9657  C C     . LEU C 1 391 ? -45.742  -84.730  -22.459 1.00 22.08  ? 391  LEU C C     1 
ATOM   9658  O O     . LEU C 1 391 ? -44.803  -84.331  -21.749 1.00 24.72  ? 391  LEU C O     1 
ATOM   9659  C CB    . LEU C 1 391 ? -44.770  -86.636  -23.821 1.00 17.72  ? 391  LEU C CB    1 
ATOM   9660  C CG    . LEU C 1 391 ? -45.381  -87.673  -22.874 1.00 17.78  ? 391  LEU C CG    1 
ATOM   9661  C CD1   . LEU C 1 391 ? -46.782  -88.049  -23.357 1.00 16.53  ? 391  LEU C CD1   1 
ATOM   9662  C CD2   . LEU C 1 391 ? -44.480  -88.916  -22.693 1.00 17.57  ? 391  LEU C CD2   1 
ATOM   9663  N N     . THR C 1 392 ? -47.019  -84.729  -22.050 1.00 19.91  ? 392  THR C N     1 
ATOM   9664  C CA    . THR C 1 392 ? -47.393  -84.358  -20.694 1.00 19.02  ? 392  THR C CA    1 
ATOM   9665  C C     . THR C 1 392 ? -48.226  -85.489  -20.111 1.00 21.70  ? 392  THR C C     1 
ATOM   9666  O O     . THR C 1 392 ? -49.220  -85.851  -20.727 1.00 25.74  ? 392  THR C O     1 
ATOM   9667  C CB    . THR C 1 392 ? -48.221  -83.069  -20.699 1.00 18.34  ? 392  THR C CB    1 
ATOM   9668  O OG1   . THR C 1 392 ? -47.450  -82.049  -21.341 1.00 20.94  ? 392  THR C OG1   1 
ATOM   9669  C CG2   . THR C 1 392 ? -48.545  -82.604  -19.288 1.00 15.67  ? 392  THR C CG2   1 
ATOM   9670  N N     . VAL C 1 393 ? -47.832  -86.025  -18.945 1.00 19.23  ? 393  VAL C N     1 
ATOM   9671  C CA    . VAL C 1 393 ? -48.588  -87.069  -18.274 1.00 21.71  ? 393  VAL C CA    1 
ATOM   9672  C C     . VAL C 1 393 ? -49.107  -86.510  -16.955 1.00 23.24  ? 393  VAL C C     1 
ATOM   9673  O O     . VAL C 1 393 ? -48.500  -85.609  -16.371 1.00 24.94  ? 393  VAL C O     1 
ATOM   9674  C CB    . VAL C 1 393 ? -47.765  -88.338  -17.986 1.00 22.27  ? 393  VAL C CB    1 
ATOM   9675  C CG1   . VAL C 1 393 ? -47.062  -88.819  -19.255 1.00 22.78  ? 393  VAL C CG1   1 
ATOM   9676  C CG2   . VAL C 1 393 ? -46.706  -88.068  -16.924 1.00 20.08  ? 393  VAL C CG2   1 
ATOM   9677  N N     . ASP C 1 394 ? -50.239  -87.049  -16.496 1.00 21.37  ? 394  ASP C N     1 
ATOM   9678  C CA    . ASP C 1 394 ? -50.653  -86.813  -15.128 1.00 21.92  ? 394  ASP C CA    1 
ATOM   9679  C C     . ASP C 1 394 ? -49.987  -87.888  -14.263 1.00 23.47  ? 394  ASP C C     1 
ATOM   9680  O O     . ASP C 1 394 ? -50.437  -89.038  -14.243 1.00 20.23  ? 394  ASP C O     1 
ATOM   9681  C CB    . ASP C 1 394 ? -52.163  -86.890  -14.959 1.00 22.90  ? 394  ASP C CB    1 
ATOM   9682  C CG    . ASP C 1 394 ? -52.645  -86.810  -13.516 1.00 26.74  ? 394  ASP C CG    1 
ATOM   9683  O OD1   . ASP C 1 394 ? -51.833  -86.396  -12.615 1.00 30.41  ? 394  ASP C OD1   1 
ATOM   9684  O OD2   . ASP C 1 394 ? -53.822  -87.178  -13.289 1.00 28.23  ? 394  ASP C OD2   1 
ATOM   9685  N N     . ALA C 1 395 ? -48.901  -87.505  -13.568 1.00 20.79  ? 395  ALA C N     1 
ATOM   9686  C CA    . ALA C 1 395 ? -48.142  -88.478  -12.805 1.00 21.78  ? 395  ALA C CA    1 
ATOM   9687  C C     . ALA C 1 395 ? -48.799  -88.640  -11.428 1.00 20.37  ? 395  ALA C C     1 
ATOM   9688  O O     . ALA C 1 395 ? -48.521  -87.886  -10.514 1.00 19.07  ? 395  ALA C O     1 
ATOM   9689  C CB    . ALA C 1 395 ? -46.677  -88.063  -12.714 1.00 18.68  ? 395  ALA C CB    1 
ATOM   9690  N N     . THR C 1 396 ? -49.706  -89.604  -11.297 1.00 21.41  ? 396  THR C N     1 
ATOM   9691  C CA    . THR C 1 396 ? -50.458  -89.766  -10.060 1.00 21.81  ? 396  THR C CA    1 
ATOM   9692  C C     . THR C 1 396 ? -49.501  -90.143  -8.930  1.00 21.01  ? 396  THR C C     1 
ATOM   9693  O O     . THR C 1 396 ? -48.443  -90.743  -9.171  1.00 19.87  ? 396  THR C O     1 
ATOM   9694  C CB    . THR C 1 396 ? -51.573  -90.791  -10.257 1.00 23.54  ? 396  THR C CB    1 
ATOM   9695  O OG1   . THR C 1 396 ? -50.956  -91.966  -10.791 1.00 22.55  ? 396  THR C OG1   1 
ATOM   9696  C CG2   . THR C 1 396 ? -52.647  -90.284  -11.207 1.00 22.14  ? 396  THR C CG2   1 
ATOM   9697  N N     . GLY C 1 397 ? -49.878  -89.764  -7.700  1.00 17.65  ? 397  GLY C N     1 
ATOM   9698  C CA    . GLY C 1 397 ? -49.036  -89.983  -6.547  1.00 17.70  ? 397  GLY C CA    1 
ATOM   9699  C C     . GLY C 1 397 ? -49.108  -91.449  -6.120  1.00 20.39  ? 397  GLY C C     1 
ATOM   9700  O O     . GLY C 1 397 ? -49.870  -92.244  -6.695  1.00 21.27  ? 397  GLY C O     1 
ATOM   9701  N N     . TYR C 1 398 ? -48.301  -91.818  -5.121  1.00 18.55  ? 398  TYR C N     1 
ATOM   9702  C CA    . TYR C 1 398 ? -48.251  -93.205  -4.697  1.00 19.12  ? 398  TYR C CA    1 
ATOM   9703  C C     . TYR C 1 398 ? -49.556  -93.595  -4.006  1.00 21.02  ? 398  TYR C C     1 
ATOM   9704  O O     . TYR C 1 398 ? -50.124  -92.822  -3.212  1.00 24.72  ? 398  TYR C O     1 
ATOM   9705  C CB    . TYR C 1 398 ? -47.111  -93.412  -3.696  1.00 19.72  ? 398  TYR C CB    1 
ATOM   9706  C CG    . TYR C 1 398 ? -45.755  -93.055  -4.276  1.00 19.62  ? 398  TYR C CG    1 
ATOM   9707  C CD1   . TYR C 1 398 ? -45.223  -93.837  -5.300  1.00 20.43  ? 398  TYR C CD1   1 
ATOM   9708  C CD2   . TYR C 1 398 ? -45.011  -91.963  -3.802  1.00 20.34  ? 398  TYR C CD2   1 
ATOM   9709  C CE1   . TYR C 1 398 ? -43.995  -93.534  -5.856  1.00 20.27  ? 398  TYR C CE1   1 
ATOM   9710  C CE2   . TYR C 1 398 ? -43.774  -91.652  -4.356  1.00 18.77  ? 398  TYR C CE2   1 
ATOM   9711  C CZ    . TYR C 1 398 ? -43.275  -92.459  -5.367  1.00 21.20  ? 398  TYR C CZ    1 
ATOM   9712  O OH    . TYR C 1 398 ? -42.097  -92.227  -6.008  1.00 26.69  ? 398  TYR C OH    1 
ATOM   9713  N N     . PRO C 1 399 ? -50.041  -94.841  -4.226  1.00 21.52  ? 399  PRO C N     1 
ATOM   9714  C CA    . PRO C 1 399 ? -51.065  -95.393  -3.345  1.00 22.39  ? 399  PRO C CA    1 
ATOM   9715  C C     . PRO C 1 399 ? -50.602  -95.344  -1.891  1.00 21.69  ? 399  PRO C C     1 
ATOM   9716  O O     . PRO C 1 399 ? -49.434  -95.636  -1.593  1.00 20.62  ? 399  PRO C O     1 
ATOM   9717  C CB    . PRO C 1 399 ? -51.221  -96.858  -3.770  1.00 21.12  ? 399  PRO C CB    1 
ATOM   9718  C CG    . PRO C 1 399 ? -50.499  -96.948  -5.099  1.00 22.35  ? 399  PRO C CG    1 
ATOM   9719  C CD    . PRO C 1 399 ? -49.535  -95.798  -5.228  1.00 22.98  ? 399  PRO C CD    1 
ATOM   9720  N N     . TYR C 1 400 ? -51.514  -94.946  -0.997  1.00 20.60  ? 400  TYR C N     1 
ATOM   9721  C CA    . TYR C 1 400 ? -51.204  -94.942  0.415   1.00 18.54  ? 400  TYR C CA    1 
ATOM   9722  C C     . TYR C 1 400 ? -50.572  -96.281  0.784   1.00 19.84  ? 400  TYR C C     1 
ATOM   9723  O O     . TYR C 1 400 ? -50.995  -97.337  0.306   1.00 19.81  ? 400  TYR C O     1 
ATOM   9724  C CB    . TYR C 1 400 ? -52.466  -94.655  1.223   1.00 17.18  ? 400  TYR C CB    1 
ATOM   9725  C CG    . TYR C 1 400 ? -52.207  -94.702  2.721   1.00 17.47  ? 400  TYR C CG    1 
ATOM   9726  C CD1   . TYR C 1 400 ? -51.614  -93.626  3.373   1.00 16.97  ? 400  TYR C CD1   1 
ATOM   9727  C CD2   . TYR C 1 400 ? -52.505  -95.844  3.464   1.00 15.73  ? 400  TYR C CD2   1 
ATOM   9728  C CE1   . TYR C 1 400 ? -51.351  -93.673  4.738   1.00 18.22  ? 400  TYR C CE1   1 
ATOM   9729  C CE2   . TYR C 1 400 ? -52.244  -95.906  4.824   1.00 16.00  ? 400  TYR C CE2   1 
ATOM   9730  C CZ    . TYR C 1 400 ? -51.673  -94.817  5.463   1.00 18.57  ? 400  TYR C CZ    1 
ATOM   9731  O OH    . TYR C 1 400 ? -51.413  -94.886  6.805   1.00 17.96  ? 400  TYR C OH    1 
ATOM   9732  N N     . GLY C 1 401 ? -49.523  -96.220  1.616   1.00 19.87  ? 401  GLY C N     1 
ATOM   9733  C CA    . GLY C 1 401 ? -48.870  -97.438  2.048   1.00 19.86  ? 401  GLY C CA    1 
ATOM   9734  C C     . GLY C 1 401 ? -47.642  -97.757  1.192   1.00 22.50  ? 401  GLY C C     1 
ATOM   9735  O O     . GLY C 1 401 ? -46.933  -98.747  1.445   1.00 21.69  ? 401  GLY C O     1 
ATOM   9736  N N     . SER C 1 402 ? -47.371  -96.933  0.168   1.00 19.57  ? 402  SER C N     1 
ATOM   9737  C CA    . SER C 1 402 ? -46.178  -97.238  -0.602  1.00 21.50  ? 402  SER C CA    1 
ATOM   9738  C C     . SER C 1 402 ? -45.492  -95.948  -1.040  1.00 21.79  ? 402  SER C C     1 
ATOM   9739  O O     . SER C 1 402 ? -46.076  -94.873  -0.950  1.00 25.16  ? 402  SER C O     1 
ATOM   9740  C CB    . SER C 1 402 ? -46.519  -98.203  -1.736  1.00 24.79  ? 402  SER C CB    1 
ATOM   9741  O OG    . SER C 1 402 ? -47.164  -97.450  -2.745  1.00 34.73  ? 402  SER C OG    1 
ATOM   9742  N N     . ASP C 1 403 ? -44.222  -96.041  -1.445  1.00 24.25  ? 403  ASP C N     1 
ATOM   9743  C CA    . ASP C 1 403 ? -43.418  -94.900  -1.866  1.00 22.57  ? 403  ASP C CA    1 
ATOM   9744  C C     . ASP C 1 403 ? -42.119  -95.439  -2.480  1.00 22.99  ? 403  ASP C C     1 
ATOM   9745  O O     . ASP C 1 403 ? -41.237  -95.912  -1.753  1.00 21.22  ? 403  ASP C O     1 
ATOM   9746  C CB    . ASP C 1 403 ? -43.153  -93.927  -0.718  1.00 23.88  ? 403  ASP C CB    1 
ATOM   9747  C CG    . ASP C 1 403 ? -42.433  -92.628  -1.098  1.00 26.52  ? 403  ASP C CG    1 
ATOM   9748  O OD1   . ASP C 1 403 ? -41.720  -92.621  -2.126  1.00 25.33  ? 403  ASP C OD1   1 
ATOM   9749  O OD2   . ASP C 1 403 ? -42.627  -91.594  -0.400  1.00 27.05  ? 403  ASP C OD2   1 
ATOM   9750  N N     . TRP C 1 404 ? -41.996  -95.328  -3.806  1.00 20.78  ? 404  TRP C N     1 
ATOM   9751  C CA    . TRP C 1 404 ? -40.932  -95.976  -4.563  1.00 20.61  ? 404  TRP C CA    1 
ATOM   9752  C C     . TRP C 1 404 ? -39.727  -95.056  -4.752  1.00 20.46  ? 404  TRP C C     1 
ATOM   9753  O O     . TRP C 1 404 ? -38.716  -95.478  -5.304  1.00 23.00  ? 404  TRP C O     1 
ATOM   9754  C CB    . TRP C 1 404 ? -41.469  -96.485  -5.922  1.00 20.57  ? 404  TRP C CB    1 
ATOM   9755  C CG    . TRP C 1 404 ? -42.466  -97.607  -5.749  1.00 21.00  ? 404  TRP C CG    1 
ATOM   9756  C CD1   . TRP C 1 404 ? -43.816  -97.482  -5.670  1.00 21.03  ? 404  TRP C CD1   1 
ATOM   9757  C CD2   . TRP C 1 404 ? -42.182  -99.015  -5.570  1.00 21.28  ? 404  TRP C CD2   1 
ATOM   9758  N NE1   . TRP C 1 404 ? -44.399  -98.693  -5.428  1.00 24.11  ? 404  TRP C NE1   1 
ATOM   9759  C CE2   . TRP C 1 404 ? -43.427  -99.660  -5.379  1.00 23.66  ? 404  TRP C CE2   1 
ATOM   9760  C CE3   . TRP C 1 404 ? -41.010  -99.790  -5.555  1.00 20.08  ? 404  TRP C CE3   1 
ATOM   9761  C CZ2   . TRP C 1 404 ? -43.538  -101.052 -5.197  1.00 24.16  ? 404  TRP C CZ2   1 
ATOM   9762  C CZ3   . TRP C 1 404 ? -41.123  -101.159 -5.353  1.00 23.32  ? 404  TRP C CZ3   1 
ATOM   9763  C CH2   . TRP C 1 404 ? -42.369  -101.787 -5.188  1.00 20.39  ? 404  TRP C CH2   1 
ATOM   9764  N N     . VAL C 1 405 ? -39.845  -93.785  -4.349  1.00 19.70  ? 405  VAL C N     1 
ATOM   9765  C CA    . VAL C 1 405 ? -38.770  -92.799  -4.468  1.00 17.57  ? 405  VAL C CA    1 
ATOM   9766  C C     . VAL C 1 405 ? -38.543  -92.389  -5.924  1.00 18.88  ? 405  VAL C C     1 
ATOM   9767  O O     . VAL C 1 405 ? -38.608  -91.204  -6.249  1.00 19.73  ? 405  VAL C O     1 
ATOM   9768  C CB    . VAL C 1 405 ? -37.442  -93.202  -3.797  1.00 17.48  ? 405  VAL C CB    1 
ATOM   9769  C CG1   . VAL C 1 405 ? -36.399  -92.071  -3.946  1.00 14.56  ? 405  VAL C CG1   1 
ATOM   9770  C CG2   . VAL C 1 405 ? -37.652  -93.630  -2.331  1.00 15.29  ? 405  VAL C CG2   1 
ATOM   9771  N N     . VAL C 1 406 ? -38.183  -93.343  -6.792  1.00 18.38  ? 406  VAL C N     1 
ATOM   9772  C CA    . VAL C 1 406 ? -38.160  -93.089  -8.229  1.00 19.30  ? 406  VAL C CA    1 
ATOM   9773  C C     . VAL C 1 406 ? -39.226  -93.991  -8.839  1.00 18.63  ? 406  VAL C C     1 
ATOM   9774  O O     . VAL C 1 406 ? -39.082  -95.214  -8.787  1.00 17.44  ? 406  VAL C O     1 
ATOM   9775  C CB    . VAL C 1 406 ? -36.779  -93.384  -8.871  1.00 18.80  ? 406  VAL C CB    1 
ATOM   9776  C CG1   . VAL C 1 406 ? -36.809  -93.255  -10.396 1.00 15.10  ? 406  VAL C CG1   1 
ATOM   9777  C CG2   . VAL C 1 406 ? -35.665  -92.533  -8.260  1.00 17.92  ? 406  VAL C CG2   1 
ATOM   9778  N N     . ARG C 1 407 ? -40.288  -93.395  -9.388  1.00 19.66  ? 407  ARG C N     1 
ATOM   9779  C CA    . ARG C 1 407 ? -41.382  -94.190  -9.946  1.00 19.64  ? 407  ARG C CA    1 
ATOM   9780  C C     . ARG C 1 407 ? -41.200  -94.271  -11.464 1.00 20.37  ? 407  ARG C C     1 
ATOM   9781  O O     . ARG C 1 407 ? -40.735  -93.310  -12.087 1.00 20.04  ? 407  ARG C O     1 
ATOM   9782  C CB    . ARG C 1 407 ? -42.724  -93.546  -9.573  1.00 20.05  ? 407  ARG C CB    1 
ATOM   9783  C CG    . ARG C 1 407 ? -43.868  -94.543  -9.492  1.00 19.03  ? 407  ARG C CG    1 
ATOM   9784  C CD    . ARG C 1 407 ? -45.217  -93.890  -9.256  1.00 19.96  ? 407  ARG C CD    1 
ATOM   9785  N NE    . ARG C 1 407 ? -46.180  -94.965  -9.046  1.00 20.64  ? 407  ARG C NE    1 
ATOM   9786  C CZ    . ARG C 1 407 ? -47.469  -94.779  -8.714  1.00 27.25  ? 407  ARG C CZ    1 
ATOM   9787  N NH1   . ARG C 1 407 ? -47.985  -93.550  -8.616  1.00 23.92  ? 407  ARG C NH1   1 
ATOM   9788  N NH2   . ARG C 1 407 ? -48.236  -95.857  -8.515  1.00 20.22  ? 407  ARG C NH2   1 
ATOM   9789  N N     . ILE C 1 408 ? -41.540  -95.418  -12.057 1.00 20.25  ? 408  ILE C N     1 
ATOM   9790  C CA    . ILE C 1 408 ? -41.228  -95.635  -13.466 1.00 21.06  ? 408  ILE C CA    1 
ATOM   9791  C C     . ILE C 1 408 ? -42.507  -95.963  -14.242 1.00 20.61  ? 408  ILE C C     1 
ATOM   9792  O O     . ILE C 1 408 ? -43.236  -96.890  -13.890 1.00 18.92  ? 408  ILE C O     1 
ATOM   9793  C CB    . ILE C 1 408 ? -40.179  -96.753  -13.632 1.00 21.44  ? 408  ILE C CB    1 
ATOM   9794  C CG1   . ILE C 1 408 ? -38.897  -96.441  -12.848 1.00 20.32  ? 408  ILE C CG1   1 
ATOM   9795  C CG2   . ILE C 1 408 ? -39.898  -97.000  -15.123 1.00 21.45  ? 408  ILE C CG2   1 
ATOM   9796  C CD1   . ILE C 1 408 ? -37.896  -97.585  -12.835 1.00 17.58  ? 408  ILE C CD1   1 
ATOM   9797  N N     . ALA C 1 409 ? -42.754  -95.192  -15.306 1.00 18.58  ? 409  ALA C N     1 
ATOM   9798  C CA    . ALA C 1 409 ? -43.889  -95.411  -16.187 1.00 20.64  ? 409  ALA C CA    1 
ATOM   9799  C C     . ALA C 1 409 ? -43.364  -95.938  -17.525 1.00 23.55  ? 409  ALA C C     1 
ATOM   9800  O O     . ALA C 1 409 ? -42.456  -95.346  -18.116 1.00 26.32  ? 409  ALA C O     1 
ATOM   9801  C CB    . ALA C 1 409 ? -44.686  -94.116  -16.385 1.00 17.36  ? 409  ALA C CB    1 
ATOM   9802  N N     . GLN C 1 410 ? -43.953  -97.044  -17.997 1.00 21.94  ? 410  GLN C N     1 
ATOM   9803  C CA    . GLN C 1 410 ? -43.612  -97.593  -19.300 1.00 20.42  ? 410  GLN C CA    1 
ATOM   9804  C C     . GLN C 1 410 ? -44.532  -97.013  -20.377 1.00 20.49  ? 410  GLN C C     1 
ATOM   9805  O O     . GLN C 1 410 ? -45.758  -96.960  -20.214 1.00 21.40  ? 410  GLN C O     1 
ATOM   9806  C CB    . GLN C 1 410 ? -43.866  -99.096  -19.283 1.00 22.38  ? 410  GLN C CB    1 
ATOM   9807  C CG    . GLN C 1 410 ? -43.435  -99.776  -20.577 1.00 26.30  ? 410  GLN C CG    1 
ATOM   9808  C CD    . GLN C 1 410 ? -43.571  -101.275 -20.480 1.00 25.89  ? 410  GLN C CD    1 
ATOM   9809  O OE1   . GLN C 1 410 ? -42.964  -101.918 -19.611 1.00 28.16  ? 410  GLN C OE1   1 
ATOM   9810  N NE2   . GLN C 1 410 ? -44.414  -101.824 -21.331 1.00 23.81  ? 410  GLN C NE2   1 
ATOM   9811  N N     . ILE C 1 411 ? -43.914  -96.551  -21.463 1.00 20.50  ? 411  ILE C N     1 
ATOM   9812  C CA    . ILE C 1 411 ? -44.612  -96.067  -22.639 1.00 23.51  ? 411  ILE C CA    1 
ATOM   9813  C C     . ILE C 1 411 ? -44.709  -97.192  -23.682 1.00 26.02  ? 411  ILE C C     1 
ATOM   9814  O O     . ILE C 1 411 ? -43.694  -97.765  -24.088 1.00 23.75  ? 411  ILE C O     1 
ATOM   9815  C CB    . ILE C 1 411 ? -43.859  -94.865  -23.229 1.00 23.35  ? 411  ILE C CB    1 
ATOM   9816  C CG1   . ILE C 1 411 ? -43.864  -93.662  -22.252 1.00 23.48  ? 411  ILE C CG1   1 
ATOM   9817  C CG2   . ILE C 1 411 ? -44.444  -94.515  -24.610 1.00 22.50  ? 411  ILE C CG2   1 
ATOM   9818  C CD1   . ILE C 1 411 ? -42.958  -92.509  -22.681 1.00 22.06  ? 411  ILE C CD1   1 
ATOM   9819  N N     . ASP C 1 412 ? -45.934  -97.481  -24.136 1.00 27.08  ? 412  ASP C N     1 
ATOM   9820  C CA    . ASP C 1 412 ? -46.215  -98.376  -25.264 1.00 28.25  ? 412  ASP C CA    1 
ATOM   9821  C C     . ASP C 1 412 ? -46.603  -97.526  -26.474 1.00 27.45  ? 412  ASP C C     1 
ATOM   9822  O O     . ASP C 1 412 ? -47.605  -96.803  -26.430 1.00 26.48  ? 412  ASP C O     1 
ATOM   9823  C CB    . ASP C 1 412 ? -47.342  -99.346  -24.923 1.00 25.10  ? 412  ASP C CB    1 
ATOM   9824  C CG    . ASP C 1 412 ? -47.054  -100.248 -23.727 1.00 33.83  ? 412  ASP C CG    1 
ATOM   9825  O OD1   . ASP C 1 412 ? -45.857  -100.380 -23.384 1.00 33.53  ? 412  ASP C OD1   1 
ATOM   9826  O OD2   . ASP C 1 412 ? -48.020  -100.773 -23.097 1.00 43.87  ? 412  ASP C OD2   1 
ATOM   9827  N N     . TYR C 1 413 ? -45.785  -97.582  -27.523 1.00 28.58  ? 413  TYR C N     1 
ATOM   9828  C CA    . TYR C 1 413 ? -46.048  -96.838  -28.751 1.00 34.84  ? 413  TYR C CA    1 
ATOM   9829  C C     . TYR C 1 413 ? -47.085  -97.551  -29.619 1.00 40.63  ? 413  TYR C C     1 
ATOM   9830  O O     . TYR C 1 413 ? -47.206  -98.776  -29.571 1.00 35.55  ? 413  TYR C O     1 
ATOM   9831  C CB    . TYR C 1 413 ? -44.766  -96.660  -29.564 1.00 26.21  ? 413  TYR C CB    1 
ATOM   9832  C CG    . TYR C 1 413 ? -43.897  -95.635  -28.860 1.00 29.67  ? 413  TYR C CG    1 
ATOM   9833  C CD1   . TYR C 1 413 ? -44.216  -94.285  -28.906 1.00 29.41  ? 413  TYR C CD1   1 
ATOM   9834  C CD2   . TYR C 1 413 ? -42.772  -96.025  -28.132 1.00 28.21  ? 413  TYR C CD2   1 
ATOM   9835  C CE1   . TYR C 1 413 ? -43.430  -93.341  -28.259 1.00 30.79  ? 413  TYR C CE1   1 
ATOM   9836  C CE2   . TYR C 1 413 ? -41.973  -95.093  -27.495 1.00 27.47  ? 413  TYR C CE2   1 
ATOM   9837  C CZ    . TYR C 1 413 ? -42.306  -93.750  -27.555 1.00 28.95  ? 413  TYR C CZ    1 
ATOM   9838  O OH    . TYR C 1 413 ? -41.513  -92.834  -26.934 1.00 27.40  ? 413  TYR C OH    1 
ATOM   9839  N N     . GLU C 1 414 ? -47.810  -96.742  -30.402 1.00 46.78  ? 414  GLU C N     1 
ATOM   9840  C CA    . GLU C 1 414 ? -48.673  -97.221  -31.466 1.00 59.43  ? 414  GLU C CA    1 
ATOM   9841  C C     . GLU C 1 414 ? -47.859  -97.931  -32.565 1.00 62.76  ? 414  GLU C C     1 
ATOM   9842  O O     . GLU C 1 414 ? -48.466  -98.825  -33.163 1.00 70.34  ? 414  GLU C O     1 
ATOM   9843  C CB    . GLU C 1 414 ? -49.550  -96.122  -32.062 1.00 63.21  ? 414  GLU C CB    1 
ATOM   9844  C CG    . GLU C 1 414 ? -50.691  -95.745  -31.118 1.00 81.14  ? 414  GLU C CG    1 
ATOM   9845  C CD    . GLU C 1 414 ? -51.677  -94.761  -31.727 1.00 93.63  ? 414  GLU C CD    1 
ATOM   9846  O OE1   . GLU C 1 414 ? -52.727  -94.587  -31.075 1.00 96.36  ? 414  GLU C OE1   1 
ATOM   9847  O OE2   . GLU C 1 414 ? -51.429  -94.168  -32.811 1.00 88.54  ? 414  GLU C OE2   1 
ATOM   9848  O OXT   . GLU C 1 414 ? -46.664  -97.577  -32.789 1.00 56.58  ? 414  GLU C OXT   1 
ATOM   9849  N N     . THR D 1 2   ? -43.787  -70.283  35.529  1.00 61.37  ? 2    THR D N     1 
ATOM   9850  C CA    . THR D 1 2   ? -43.983  -71.210  36.674  1.00 84.96  ? 2    THR D CA    1 
ATOM   9851  C C     . THR D 1 2   ? -42.951  -72.320  36.557  1.00 91.03  ? 2    THR D C     1 
ATOM   9852  O O     . THR D 1 2   ? -42.378  -72.539  35.491  1.00 97.15  ? 2    THR D O     1 
ATOM   9853  C CB    . THR D 1 2   ? -45.393  -71.818  36.761  1.00 83.70  ? 2    THR D CB    1 
ATOM   9854  O OG1   . THR D 1 2   ? -46.399  -70.893  36.362  1.00 86.15  ? 2    THR D OG1   1 
ATOM   9855  C CG2   . THR D 1 2   ? -45.701  -72.329  38.165  1.00 72.02  ? 2    THR D CG2   1 
ATOM   9856  N N     . GLU D 1 3   ? -42.784  -73.071  37.653  1.00 88.22  ? 3    GLU D N     1 
ATOM   9857  C CA    . GLU D 1 3   ? -41.932  -74.250  37.673  1.00 79.94  ? 3    GLU D CA    1 
ATOM   9858  C C     . GLU D 1 3   ? -42.788  -75.476  37.346  1.00 64.68  ? 3    GLU D C     1 
ATOM   9859  O O     . GLU D 1 3   ? -43.926  -75.576  37.789  1.00 65.24  ? 3    GLU D O     1 
ATOM   9860  C CB    . GLU D 1 3   ? -41.228  -74.153  39.021  1.00 88.37  ? 3    GLU D CB    1 
ATOM   9861  C CG    . GLU D 1 3   ? -40.420  -75.385  39.397  1.00 110.53 ? 3    GLU D CG    1 
ATOM   9862  C CD    . GLU D 1 3   ? -40.213  -75.608  40.885  1.00 126.43 ? 3    GLU D CD    1 
ATOM   9863  O OE1   . GLU D 1 3   ? -41.017  -75.120  41.712  1.00 132.98 ? 3    GLU D OE1   1 
ATOM   9864  O OE2   . GLU D 1 3   ? -39.216  -76.281  41.233  1.00 112.83 ? 3    GLU D OE2   1 
ATOM   9865  N N     . PRO D 1 4   ? -42.313  -76.398  36.467  1.00 49.13  ? 4    PRO D N     1 
ATOM   9866  C CA    . PRO D 1 4   ? -43.052  -77.616  36.172  1.00 38.90  ? 4    PRO D CA    1 
ATOM   9867  C C     . PRO D 1 4   ? -43.378  -78.444  37.412  1.00 35.08  ? 4    PRO D C     1 
ATOM   9868  O O     . PRO D 1 4   ? -42.538  -78.572  38.291  1.00 33.46  ? 4    PRO D O     1 
ATOM   9869  C CB    . PRO D 1 4   ? -42.119  -78.379  35.242  1.00 36.62  ? 4    PRO D CB    1 
ATOM   9870  C CG    . PRO D 1 4   ? -40.798  -77.645  35.286  1.00 39.25  ? 4    PRO D CG    1 
ATOM   9871  C CD    . PRO D 1 4   ? -41.071  -76.267  35.687  1.00 40.98  ? 4    PRO D CD    1 
ATOM   9872  N N     . LEU D 1 5   ? -44.594  -79.005  37.466  1.00 32.86  ? 5    LEU D N     1 
ATOM   9873  C CA    . LEU D 1 5   ? -44.938  -80.030  38.442  1.00 32.33  ? 5    LEU D CA    1 
ATOM   9874  C C     . LEU D 1 5   ? -43.869  -81.133  38.433  1.00 31.17  ? 5    LEU D C     1 
ATOM   9875  O O     . LEU D 1 5   ? -43.265  -81.427  37.390  1.00 27.41  ? 5    LEU D O     1 
ATOM   9876  C CB    . LEU D 1 5   ? -46.307  -80.628  38.113  1.00 30.28  ? 5    LEU D CB    1 
ATOM   9877  C CG    . LEU D 1 5   ? -47.520  -79.694  38.184  1.00 33.89  ? 5    LEU D CG    1 
ATOM   9878  C CD1   . LEU D 1 5   ? -48.761  -80.438  37.668  1.00 28.28  ? 5    LEU D CD1   1 
ATOM   9879  C CD2   . LEU D 1 5   ? -47.710  -79.279  39.641  1.00 28.69  ? 5    LEU D CD2   1 
ATOM   9880  N N     . PRO D 1 6   ? -43.592  -81.801  39.577  1.00 31.29  ? 6    PRO D N     1 
ATOM   9881  C CA    . PRO D 1 6   ? -42.655  -82.924  39.599  1.00 28.54  ? 6    PRO D CA    1 
ATOM   9882  C C     . PRO D 1 6   ? -42.791  -83.920  38.448  1.00 27.43  ? 6    PRO D C     1 
ATOM   9883  O O     . PRO D 1 6   ? -41.782  -84.370  37.895  1.00 27.33  ? 6    PRO D O     1 
ATOM   9884  C CB    . PRO D 1 6   ? -42.803  -83.526  41.020  1.00 26.14  ? 6    PRO D CB    1 
ATOM   9885  C CG    . PRO D 1 6   ? -43.250  -82.311  41.848  1.00 25.06  ? 6    PRO D CG    1 
ATOM   9886  C CD    . PRO D 1 6   ? -44.079  -81.429  40.917  1.00 27.87  ? 6    PRO D CD    1 
ATOM   9887  N N     . ARG D 1 7   ? -44.029  -84.315  38.105  1.00 25.75  ? 7    ARG D N     1 
ATOM   9888  C CA    . ARG D 1 7   ? -44.185  -85.401  37.151  1.00 24.52  ? 7    ARG D CA    1 
ATOM   9889  C C     . ARG D 1 7   ? -43.753  -84.916  35.755  1.00 29.57  ? 7    ARG D C     1 
ATOM   9890  O O     . ARG D 1 7   ? -43.261  -85.713  34.945  1.00 23.97  ? 7    ARG D O     1 
ATOM   9891  C CB    . ARG D 1 7   ? -45.588  -86.006  37.130  1.00 21.43  ? 7    ARG D CB    1 
ATOM   9892  C CG    . ARG D 1 7   ? -46.694  -85.119  36.580  1.00 20.92  ? 7    ARG D CG    1 
ATOM   9893  C CD    . ARG D 1 7   ? -48.019  -85.851  36.299  1.00 21.18  ? 7    ARG D CD    1 
ATOM   9894  N NE    . ARG D 1 7   ? -49.043  -84.900  35.827  1.00 25.55  ? 7    ARG D NE    1 
ATOM   9895  C CZ    . ARG D 1 7   ? -49.678  -84.029  36.634  1.00 26.33  ? 7    ARG D CZ    1 
ATOM   9896  N NH1   . ARG D 1 7   ? -49.507  -84.139  37.942  1.00 22.76  ? 7    ARG D NH1   1 
ATOM   9897  N NH2   . ARG D 1 7   ? -50.492  -83.093  36.138  1.00 22.55  ? 7    ARG D NH2   1 
ATOM   9898  N N     . ILE D 1 8   ? -43.893  -83.602  35.506  1.00 25.07  ? 8    ILE D N     1 
ATOM   9899  C CA    . ILE D 1 8   ? -43.520  -83.006  34.237  1.00 25.36  ? 8    ILE D CA    1 
ATOM   9900  C C     . ILE D 1 8   ? -42.003  -82.807  34.138  1.00 25.96  ? 8    ILE D C     1 
ATOM   9901  O O     . ILE D 1 8   ? -41.417  -83.057  33.080  1.00 27.09  ? 8    ILE D O     1 
ATOM   9902  C CB    . ILE D 1 8   ? -44.353  -81.737  33.971  1.00 23.80  ? 8    ILE D CB    1 
ATOM   9903  C CG1   . ILE D 1 8   ? -45.847  -82.098  33.828  1.00 23.32  ? 8    ILE D CG1   1 
ATOM   9904  C CG2   . ILE D 1 8   ? -43.834  -80.991  32.741  1.00 21.59  ? 8    ILE D CG2   1 
ATOM   9905  C CD1   . ILE D 1 8   ? -46.763  -80.916  33.581  1.00 23.23  ? 8    ILE D CD1   1 
ATOM   9906  N N     . GLN D 1 9   ? -41.363  -82.415  35.242  1.00 28.96  ? 9    GLN D N     1 
ATOM   9907  C CA    . GLN D 1 9   ? -39.905  -82.390  35.345  1.00 30.09  ? 9    GLN D CA    1 
ATOM   9908  C C     . GLN D 1 9   ? -39.362  -83.783  35.028  1.00 26.87  ? 9    GLN D C     1 
ATOM   9909  O O     . GLN D 1 9   ? -38.382  -83.917  34.293  1.00 28.77  ? 9    GLN D O     1 
ATOM   9910  C CB    . GLN D 1 9   ? -39.392  -82.068  36.750  1.00 35.86  ? 9    GLN D CB    1 
ATOM   9911  C CG    . GLN D 1 9   ? -39.052  -80.612  37.037  1.00 56.42  ? 9    GLN D CG    1 
ATOM   9912  C CD    . GLN D 1 9   ? -39.043  -80.296  38.526  1.00 72.07  ? 9    GLN D CD    1 
ATOM   9913  O OE1   . GLN D 1 9   ? -39.776  -79.429  39.020  1.00 62.28  ? 9    GLN D OE1   1 
ATOM   9914  N NE2   . GLN D 1 9   ? -38.239  -81.020  39.290  1.00 80.74  ? 9    GLN D NE2   1 
ATOM   9915  N N     . HIS D 1 10  ? -39.998  -84.829  35.586  1.00 24.33  ? 10   HIS D N     1 
ATOM   9916  C CA    . HIS D 1 10  ? -39.531  -86.185  35.357  1.00 27.38  ? 10   HIS D CA    1 
ATOM   9917  C C     . HIS D 1 10  ? -39.694  -86.525  33.870  1.00 25.98  ? 10   HIS D C     1 
ATOM   9918  O O     . HIS D 1 10  ? -38.819  -87.179  33.296  1.00 27.04  ? 10   HIS D O     1 
ATOM   9919  C CB    . HIS D 1 10  ? -40.115  -87.175  36.378  1.00 25.87  ? 10   HIS D CB    1 
ATOM   9920  C CG    . HIS D 1 10  ? -39.643  -88.590  36.180  1.00 43.51  ? 10   HIS D CG    1 
ATOM   9921  N ND1   . HIS D 1 10  ? -38.305  -88.940  36.182  1.00 62.86  ? 10   HIS D ND1   1 
ATOM   9922  C CD2   . HIS D 1 10  ? -40.292  -89.745  35.909  1.00 47.14  ? 10   HIS D CD2   1 
ATOM   9923  C CE1   . HIS D 1 10  ? -38.169  -90.249  35.965  1.00 54.42  ? 10   HIS D CE1   1 
ATOM   9924  N NE2   . HIS D 1 10  ? -39.358  -90.760  35.821  1.00 41.30  ? 10   HIS D NE2   1 
ATOM   9925  N N     . TYR D 1 11  ? -40.795  -86.050  33.266  1.00 18.74  ? 11   TYR D N     1 
ATOM   9926  C CA    . TYR D 1 11  ? -41.084  -86.305  31.862  1.00 20.04  ? 11   TYR D CA    1 
ATOM   9927  C C     . TYR D 1 11  ? -39.975  -85.718  30.975  1.00 20.63  ? 11   TYR D C     1 
ATOM   9928  O O     . TYR D 1 11  ? -39.466  -86.387  30.080  1.00 20.62  ? 11   TYR D O     1 
ATOM   9929  C CB    . TYR D 1 11  ? -42.472  -85.761  31.492  1.00 19.27  ? 11   TYR D CB    1 
ATOM   9930  C CG    . TYR D 1 11  ? -42.699  -85.818  29.989  1.00 16.49  ? 11   TYR D CG    1 
ATOM   9931  C CD1   . TYR D 1 11  ? -43.120  -86.996  29.362  1.00 14.32  ? 11   TYR D CD1   1 
ATOM   9932  C CD2   . TYR D 1 11  ? -42.459  -84.690  29.201  1.00 14.95  ? 11   TYR D CD2   1 
ATOM   9933  C CE1   . TYR D 1 11  ? -43.313  -87.046  27.994  1.00 15.10  ? 11   TYR D CE1   1 
ATOM   9934  C CE2   . TYR D 1 11  ? -42.637  -84.728  27.831  1.00 16.00  ? 11   TYR D CE2   1 
ATOM   9935  C CZ    . TYR D 1 11  ? -43.074  -85.911  27.232  1.00 17.37  ? 11   TYR D CZ    1 
ATOM   9936  O OH    . TYR D 1 11  ? -43.225  -85.936  25.880  1.00 19.10  ? 11   TYR D OH    1 
ATOM   9937  N N     . GLU D 1 12  ? -39.585  -84.471  31.244  1.00 19.95  ? 12   GLU D N     1 
ATOM   9938  C CA    . GLU D 1 12  ? -38.573  -83.807  30.434  1.00 23.81  ? 12   GLU D CA    1 
ATOM   9939  C C     . GLU D 1 12  ? -37.220  -84.505  30.561  1.00 25.42  ? 12   GLU D C     1 
ATOM   9940  O O     . GLU D 1 12  ? -36.409  -84.406  29.641  1.00 24.19  ? 12   GLU D O     1 
ATOM   9941  C CB    . GLU D 1 12  ? -38.483  -82.312  30.740  1.00 21.58  ? 12   GLU D CB    1 
ATOM   9942  C CG    . GLU D 1 12  ? -39.797  -81.586  30.467  1.00 23.78  ? 12   GLU D CG    1 
ATOM   9943  C CD    . GLU D 1 12  ? -39.670  -80.080  30.611  1.00 31.60  ? 12   GLU D CD    1 
ATOM   9944  O OE1   . GLU D 1 12  ? -39.075  -79.623  31.661  1.00 34.13  ? 12   GLU D OE1   1 
ATOM   9945  O OE2   . GLU D 1 12  ? -40.179  -79.355  29.686  1.00 30.49  ? 12   GLU D OE2   1 
ATOM   9946  N N     . ASP D 1 13  ? -36.993  -85.211  31.677  1.00 21.67  ? 13   ASP D N     1 
ATOM   9947  C CA    . ASP D 1 13  ? -35.749  -85.939  31.856  1.00 21.88  ? 13   ASP D CA    1 
ATOM   9948  C C     . ASP D 1 13  ? -35.741  -87.236  31.067  1.00 22.64  ? 13   ASP D C     1 
ATOM   9949  O O     . ASP D 1 13  ? -34.694  -87.872  30.961  1.00 25.45  ? 13   ASP D O     1 
ATOM   9950  C CB    . ASP D 1 13  ? -35.484  -86.304  33.311  1.00 24.45  ? 13   ASP D CB    1 
ATOM   9951  C CG    . ASP D 1 13  ? -34.913  -85.199  34.188  1.00 25.66  ? 13   ASP D CG    1 
ATOM   9952  O OD1   . ASP D 1 13  ? -34.481  -84.158  33.642  1.00 28.17  ? 13   ASP D OD1   1 
ATOM   9953  O OD2   . ASP D 1 13  ? -34.921  -85.375  35.416  1.00 33.69  ? 13   ASP D OD2   1 
ATOM   9954  N N     . LEU D 1 14  ? -36.911  -87.674  30.587  1.00 22.68  ? 14   LEU D N     1 
ATOM   9955  C CA    . LEU D 1 14  ? -36.967  -88.927  29.841  1.00 19.21  ? 14   LEU D CA    1 
ATOM   9956  C C     . LEU D 1 14  ? -36.223  -88.738  28.512  1.00 21.56  ? 14   LEU D C     1 
ATOM   9957  O O     . LEU D 1 14  ? -35.515  -89.644  28.062  1.00 19.83  ? 14   LEU D O     1 
ATOM   9958  C CB    . LEU D 1 14  ? -38.419  -89.337  29.616  1.00 17.37  ? 14   LEU D CB    1 
ATOM   9959  C CG    . LEU D 1 14  ? -39.244  -89.591  30.885  1.00 17.98  ? 14   LEU D CG    1 
ATOM   9960  C CD1   . LEU D 1 14  ? -40.692  -89.823  30.425  1.00 18.26  ? 14   LEU D CD1   1 
ATOM   9961  C CD2   . LEU D 1 14  ? -38.727  -90.767  31.719  1.00 16.22  ? 14   LEU D CD2   1 
ATOM   9962  N N     . GLY D 1 15  ? -36.422  -87.562  27.867  1.00 20.48  ? 15   GLY D N     1 
ATOM   9963  C CA    . GLY D 1 15  ? -35.691  -87.198  26.665  1.00 20.29  ? 15   GLY D CA    1 
ATOM   9964  C C     . GLY D 1 15  ? -36.226  -87.909  25.419  1.00 20.46  ? 15   GLY D C     1 
ATOM   9965  O O     . GLY D 1 15  ? -36.732  -87.269  24.483  1.00 19.53  ? 15   GLY D O     1 
ATOM   9966  N N     . LEU D 1 16  ? -36.082  -89.241  25.402  1.00 20.70  ? 16   LEU D N     1 
ATOM   9967  C CA    . LEU D 1 16  ? -36.293  -90.036  24.203  1.00 19.64  ? 16   LEU D CA    1 
ATOM   9968  C C     . LEU D 1 16  ? -37.248  -91.172  24.542  1.00 20.85  ? 16   LEU D C     1 
ATOM   9969  O O     . LEU D 1 16  ? -37.068  -91.881  25.549  1.00 19.41  ? 16   LEU D O     1 
ATOM   9970  C CB    . LEU D 1 16  ? -34.943  -90.584  23.733  1.00 17.07  ? 16   LEU D CB    1 
ATOM   9971  C CG    . LEU D 1 16  ? -35.007  -91.669  22.647  1.00 20.03  ? 16   LEU D CG    1 
ATOM   9972  C CD1   . LEU D 1 16  ? -35.583  -91.224  21.297  1.00 17.07  ? 16   LEU D CD1   1 
ATOM   9973  C CD2   . LEU D 1 16  ? -33.593  -92.250  22.465  1.00 19.20  ? 16   LEU D CD2   1 
ATOM   9974  N N     . GLY D 1 17  ? -38.273  -91.341  23.699  1.00 20.19  ? 17   GLY D N     1 
ATOM   9975  C CA    . GLY D 1 17  ? -39.162  -92.481  23.831  1.00 18.05  ? 17   GLY D CA    1 
ATOM   9976  C C     . GLY D 1 17  ? -39.257  -93.239  22.512  1.00 19.87  ? 17   GLY D C     1 
ATOM   9977  O O     . GLY D 1 17  ? -38.997  -92.698  21.436  1.00 21.56  ? 17   GLY D O     1 
ATOM   9978  N N     . LEU D 1 18  ? -39.685  -94.494  22.611  1.00 19.97  ? 18   LEU D N     1 
ATOM   9979  C CA    . LEU D 1 18  ? -39.992  -95.280  21.433  1.00 21.02  ? 18   LEU D CA    1 
ATOM   9980  C C     . LEU D 1 18  ? -41.507  -95.312  21.242  1.00 21.12  ? 18   LEU D C     1 
ATOM   9981  O O     . LEU D 1 18  ? -42.263  -95.575  22.191  1.00 21.94  ? 18   LEU D O     1 
ATOM   9982  C CB    . LEU D 1 18  ? -39.427  -96.646  21.790  1.00 22.95  ? 18   LEU D CB    1 
ATOM   9983  C CG    . LEU D 1 18  ? -39.347  -97.616  20.629  1.00 33.98  ? 18   LEU D CG    1 
ATOM   9984  C CD1   . LEU D 1 18  ? -38.298  -97.012  19.687  1.00 39.76  ? 18   LEU D CD1   1 
ATOM   9985  C CD2   . LEU D 1 18  ? -38.936  -99.004  21.084  1.00 34.39  ? 18   LEU D CD2   1 
ATOM   9986  N N     . PHE D 1 19  ? -41.958  -94.968  20.026  1.00 20.27  ? 19   PHE D N     1 
ATOM   9987  C CA    . PHE D 1 19  ? -43.362  -95.063  19.645  1.00 18.66  ? 19   PHE D CA    1 
ATOM   9988  C C     . PHE D 1 19  ? -43.558  -96.388  18.912  1.00 19.17  ? 19   PHE D C     1 
ATOM   9989  O O     . PHE D 1 19  ? -42.753  -96.706  18.026  1.00 19.67  ? 19   PHE D O     1 
ATOM   9990  C CB    . PHE D 1 19  ? -43.637  -93.912  18.681  1.00 17.95  ? 19   PHE D CB    1 
ATOM   9991  C CG    . PHE D 1 19  ? -45.041  -93.316  18.697  1.00 21.04  ? 19   PHE D CG    1 
ATOM   9992  C CD1   . PHE D 1 19  ? -46.147  -94.058  19.131  1.00 19.79  ? 19   PHE D CD1   1 
ATOM   9993  C CD2   . PHE D 1 19  ? -45.250  -92.003  18.244  1.00 23.27  ? 19   PHE D CD2   1 
ATOM   9994  C CE1   . PHE D 1 19  ? -47.421  -93.510  19.125  1.00 19.95  ? 19   PHE D CE1   1 
ATOM   9995  C CE2   . PHE D 1 19  ? -46.527  -91.441  18.261  1.00 25.71  ? 19   PHE D CE2   1 
ATOM   9996  C CZ    . PHE D 1 19  ? -47.607  -92.182  18.718  1.00 24.43  ? 19   PHE D CZ    1 
ATOM   9997  N N     . ILE D 1 20  ? -44.608  -97.147  19.267  1.00 18.95  ? 20   ILE D N     1 
ATOM   9998  C CA    . ILE D 1 20  ? -44.866  -98.424  18.600  1.00 19.14  ? 20   ILE D CA    1 
ATOM   9999  C C     . ILE D 1 20  ? -46.286  -98.484  18.038  1.00 20.36  ? 20   ILE D C     1 
ATOM   10000 O O     . ILE D 1 20  ? -47.255  -98.364  18.806  1.00 22.69  ? 20   ILE D O     1 
ATOM   10001 C CB    . ILE D 1 20  ? -44.611  -99.581  19.583  1.00 22.80  ? 20   ILE D CB    1 
ATOM   10002 C CG1   . ILE D 1 20  ? -43.121  -99.562  19.978  1.00 24.63  ? 20   ILE D CG1   1 
ATOM   10003 C CG2   . ILE D 1 20  ? -45.010  -100.934 18.960  1.00 21.39  ? 20   ILE D CG2   1 
ATOM   10004 C CD1   . ILE D 1 20  ? -42.755  -100.648 20.938  1.00 41.00  ? 20   ILE D CD1   1 
ATOM   10005 N N     . HIS D 1 21  ? -46.380  -98.664  16.709  1.00 16.91  ? 21   HIS D N     1 
ATOM   10006 C CA    . HIS D 1 21  ? -47.643  -98.805  16.018  1.00 17.73  ? 21   HIS D CA    1 
ATOM   10007 C C     . HIS D 1 21  ? -47.830  -100.272 15.667  1.00 18.86  ? 21   HIS D C     1 
ATOM   10008 O O     . HIS D 1 21  ? -47.050  -100.858 14.890  1.00 17.66  ? 21   HIS D O     1 
ATOM   10009 C CB    . HIS D 1 21  ? -47.676  -97.970  14.729  1.00 17.84  ? 21   HIS D CB    1 
ATOM   10010 C CG    . HIS D 1 21  ? -48.063  -96.555  14.989  1.00 18.32  ? 21   HIS D CG    1 
ATOM   10011 N ND1   . HIS D 1 21  ? -47.197  -95.674  15.606  1.00 18.13  ? 21   HIS D ND1   1 
ATOM   10012 C CD2   . HIS D 1 21  ? -49.208  -95.870  14.780  1.00 16.80  ? 21   HIS D CD2   1 
ATOM   10013 C CE1   . HIS D 1 21  ? -47.791  -94.481  15.768  1.00 17.73  ? 21   HIS D CE1   1 
ATOM   10014 N NE2   . HIS D 1 21  ? -48.997  -94.583  15.259  1.00 16.94  ? 21   HIS D NE2   1 
ATOM   10015 N N     . TRP D 1 22  ? -48.906  -100.835 16.215  1.00 19.55  ? 22   TRP D N     1 
ATOM   10016 C CA    . TRP D 1 22  ? -49.250  -102.207 15.913  1.00 20.58  ? 22   TRP D CA    1 
ATOM   10017 C C     . TRP D 1 22  ? -50.758  -102.365 16.083  1.00 22.11  ? 22   TRP D C     1 
ATOM   10018 O O     . TRP D 1 22  ? -51.302  -102.001 17.133  1.00 20.27  ? 22   TRP D O     1 
ATOM   10019 C CB    . TRP D 1 22  ? -48.515  -103.101 16.904  1.00 18.38  ? 22   TRP D CB    1 
ATOM   10020 C CG    . TRP D 1 22  ? -48.736  -104.566 16.663  1.00 19.78  ? 22   TRP D CG    1 
ATOM   10021 C CD1   . TRP D 1 22  ? -48.859  -105.222 15.474  1.00 19.28  ? 22   TRP D CD1   1 
ATOM   10022 C CD2   . TRP D 1 22  ? -48.840  -105.565 17.699  1.00 19.51  ? 22   TRP D CD2   1 
ATOM   10023 N NE1   . TRP D 1 22  ? -49.012  -106.572 15.694  1.00 20.01  ? 22   TRP D NE1   1 
ATOM   10024 C CE2   . TRP D 1 22  ? -49.007  -106.807 17.049  1.00 19.44  ? 22   TRP D CE2   1 
ATOM   10025 C CE3   . TRP D 1 22  ? -48.793  -105.511 19.102  1.00 21.89  ? 22   TRP D CE3   1 
ATOM   10026 C CZ2   . TRP D 1 22  ? -49.142  -107.989 17.764  1.00 18.00  ? 22   TRP D CZ2   1 
ATOM   10027 C CZ3   . TRP D 1 22  ? -48.912  -106.686 19.805  1.00 20.10  ? 22   TRP D CZ3   1 
ATOM   10028 C CH2   . TRP D 1 22  ? -49.098  -107.905 19.142  1.00 18.58  ? 22   TRP D CH2   1 
ATOM   10029 N N     . GLY D 1 23  ? -51.412  -102.905 15.051  1.00 20.32  ? 23   GLY D N     1 
ATOM   10030 C CA    . GLY D 1 23  ? -52.851  -103.143 15.092  1.00 21.27  ? 23   GLY D CA    1 
ATOM   10031 C C     . GLY D 1 23  ? -53.226  -104.121 13.988  1.00 22.12  ? 23   GLY D C     1 
ATOM   10032 O O     . GLY D 1 23  ? -52.333  -104.772 13.431  1.00 21.95  ? 23   GLY D O     1 
ATOM   10033 N N     . LEU D 1 24  ? -54.521  -104.226 13.665  1.00 20.03  ? 24   LEU D N     1 
ATOM   10034 C CA    . LEU D 1 24  ? -54.923  -105.156 12.616  1.00 20.74  ? 24   LEU D CA    1 
ATOM   10035 C C     . LEU D 1 24  ? -54.288  -104.714 11.291  1.00 21.03  ? 24   LEU D C     1 
ATOM   10036 O O     . LEU D 1 24  ? -53.928  -105.554 10.482  1.00 22.29  ? 24   LEU D O     1 
ATOM   10037 C CB    . LEU D 1 24  ? -56.448  -105.267 12.488  1.00 20.74  ? 24   LEU D CB    1 
ATOM   10038 C CG    . LEU D 1 24  ? -57.194  -105.727 13.749  1.00 24.29  ? 24   LEU D CG    1 
ATOM   10039 C CD1   . LEU D 1 24  ? -58.693  -105.712 13.520  1.00 21.56  ? 24   LEU D CD1   1 
ATOM   10040 C CD2   . LEU D 1 24  ? -56.692  -107.060 14.312  1.00 20.57  ? 24   LEU D CD2   1 
ATOM   10041 N N     . TYR D 1 25  ? -54.145  -103.390 11.087  1.00 18.04  ? 25   TYR D N     1 
ATOM   10042 C CA    . TYR D 1 25  ? -53.583  -102.839 9.863   1.00 18.77  ? 25   TYR D CA    1 
ATOM   10043 C C     . TYR D 1 25  ? -52.215  -103.458 9.561   1.00 20.92  ? 25   TYR D C     1 
ATOM   10044 O O     . TYR D 1 25  ? -51.842  -103.592 8.394   1.00 22.63  ? 25   TYR D O     1 
ATOM   10045 C CB    . TYR D 1 25  ? -53.404  -101.323 9.917   1.00 18.67  ? 25   TYR D CB    1 
ATOM   10046 C CG    . TYR D 1 25  ? -52.849  -100.812 11.248  1.00 19.76  ? 25   TYR D CG    1 
ATOM   10047 C CD1   . TYR D 1 25  ? -51.472  -100.788 11.507  1.00 19.37  ? 25   TYR D CD1   1 
ATOM   10048 C CD2   . TYR D 1 25  ? -53.712  -100.340 12.241  1.00 16.73  ? 25   TYR D CD2   1 
ATOM   10049 C CE1   . TYR D 1 25  ? -50.976  -100.324 12.723  1.00 18.40  ? 25   TYR D CE1   1 
ATOM   10050 C CE2   . TYR D 1 25  ? -53.227  -99.880  13.452  1.00 18.58  ? 25   TYR D CE2   1 
ATOM   10051 C CZ    . TYR D 1 25  ? -51.853  -99.868  13.698  1.00 20.39  ? 25   TYR D CZ    1 
ATOM   10052 O OH    . TYR D 1 25  ? -51.373  -99.436  14.922  1.00 21.01  ? 25   TYR D OH    1 
ATOM   10053 N N     . SER D 1 26  ? -51.471  -103.842 10.608  1.00 20.73  ? 26   SER D N     1 
ATOM   10054 C CA    . SER D 1 26  ? -50.116  -104.343 10.438  1.00 21.03  ? 26   SER D CA    1 
ATOM   10055 C C     . SER D 1 26  ? -50.097  -105.579 9.537   1.00 22.03  ? 26   SER D C     1 
ATOM   10056 O O     . SER D 1 26  ? -49.109  -105.842 8.836   1.00 22.30  ? 26   SER D O     1 
ATOM   10057 C CB    . SER D 1 26  ? -49.475  -104.646 11.778  1.00 21.63  ? 26   SER D CB    1 
ATOM   10058 O OG    . SER D 1 26  ? -49.523  -103.487 12.612  1.00 22.33  ? 26   SER D OG    1 
ATOM   10059 N N     . GLN D 1 27  ? -51.185  -106.350 9.543   1.00 22.01  ? 27   GLN D N     1 
ATOM   10060 C CA    . GLN D 1 27  ? -51.211  -107.559 8.735   1.00 22.38  ? 27   GLN D CA    1 
ATOM   10061 C C     . GLN D 1 27  ? -51.160  -107.236 7.244   1.00 24.80  ? 27   GLN D C     1 
ATOM   10062 O O     . GLN D 1 27  ? -50.719  -108.075 6.477   1.00 25.89  ? 27   GLN D O     1 
ATOM   10063 C CB    . GLN D 1 27  ? -52.407  -108.461 9.004   1.00 21.39  ? 27   GLN D CB    1 
ATOM   10064 C CG    . GLN D 1 27  ? -52.267  -109.222 10.310  1.00 26.90  ? 27   GLN D CG    1 
ATOM   10065 C CD    . GLN D 1 27  ? -53.587  -109.831 10.721  1.00 28.84  ? 27   GLN D CD    1 
ATOM   10066 O OE1   . GLN D 1 27  ? -54.237  -109.381 11.677  1.00 31.21  ? 27   GLN D OE1   1 
ATOM   10067 N NE2   . GLN D 1 27  ? -53.997  -110.842 9.973   1.00 24.43  ? 27   GLN D NE2   1 
ATOM   10068 N N     . MET D 1 28  ? -51.591  -106.047 6.821   1.00 22.60  ? 28   MET D N     1 
ATOM   10069 C CA    . MET D 1 28  ? -51.638  -105.760 5.400   1.00 25.54  ? 28   MET D CA    1 
ATOM   10070 C C     . MET D 1 28  ? -50.376  -105.017 4.938   1.00 26.54  ? 28   MET D C     1 
ATOM   10071 O O     . MET D 1 28  ? -50.118  -104.954 3.732   1.00 27.23  ? 28   MET D O     1 
ATOM   10072 C CB    . MET D 1 28  ? -52.772  -104.785 5.125   1.00 25.34  ? 28   MET D CB    1 
ATOM   10073 C CG    . MET D 1 28  ? -54.021  -105.147 5.865   1.00 36.68  ? 28   MET D CG    1 
ATOM   10074 S SD    . MET D 1 28  ? -55.153  -105.941 4.724   1.00 61.38  ? 28   MET D SD    1 
ATOM   10075 C CE    . MET D 1 28  ? -54.337  -107.508 4.377   1.00 35.77  ? 28   MET D CE    1 
ATOM   10076 N N     . ALA D 1 29  ? -49.671  -104.341 5.868   1.00 22.45  ? 29   ALA D N     1 
ATOM   10077 C CA    . ALA D 1 29  ? -48.385  -103.724 5.578   1.00 22.68  ? 29   ALA D CA    1 
ATOM   10078 C C     . ALA D 1 29  ? -48.544  -102.647 4.496   1.00 23.49  ? 29   ALA D C     1 
ATOM   10079 O O     . ALA D 1 29  ? -47.664  -102.476 3.638   1.00 22.48  ? 29   ALA D O     1 
ATOM   10080 C CB    . ALA D 1 29  ? -47.342  -104.797 5.224   1.00 16.64  ? 29   ALA D CB    1 
ATOM   10081 N N     . VAL D 1 30  ? -49.670  -101.920 4.558   1.00 21.48  ? 30   VAL D N     1 
ATOM   10082 C CA    . VAL D 1 30  ? -49.884  -100.802 3.655   1.00 21.63  ? 30   VAL D CA    1 
ATOM   10083 C C     . VAL D 1 30  ? -50.317  -99.577  4.457   1.00 23.80  ? 30   VAL D C     1 
ATOM   10084 O O     . VAL D 1 30  ? -51.104  -98.795  3.960   1.00 26.25  ? 30   VAL D O     1 
ATOM   10085 C CB    . VAL D 1 30  ? -50.812  -101.099 2.457   1.00 20.79  ? 30   VAL D CB    1 
ATOM   10086 C CG1   . VAL D 1 30  ? -50.144  -102.022 1.405   1.00 18.00  ? 30   VAL D CG1   1 
ATOM   10087 C CG2   . VAL D 1 30  ? -52.161  -101.643 2.899   1.00 16.93  ? 30   VAL D CG2   1 
ATOM   10088 N N     . GLY D 1 31  ? -49.770  -99.380  5.674   1.00 23.16  ? 31   GLY D N     1 
ATOM   10089 C CA    . GLY D 1 31  ? -50.051  -98.156  6.423   1.00 21.48  ? 31   GLY D CA    1 
ATOM   10090 C C     . GLY D 1 31  ? -51.210  -98.332  7.412   1.00 23.64  ? 31   GLY D C     1 
ATOM   10091 O O     . GLY D 1 31  ? -52.119  -99.133  7.171   1.00 19.81  ? 31   GLY D O     1 
ATOM   10092 N N     . GLU D 1 32  ? -51.186  -97.559  8.519   1.00 20.59  ? 32   GLU D N     1 
ATOM   10093 C CA    . GLU D 1 32  ? -52.174  -97.734  9.576   1.00 22.19  ? 32   GLU D CA    1 
ATOM   10094 C C     . GLU D 1 32  ? -53.537  -97.147  9.182   1.00 24.40  ? 32   GLU D C     1 
ATOM   10095 O O     . GLU D 1 32  ? -54.540  -97.523  9.770   1.00 23.10  ? 32   GLU D O     1 
ATOM   10096 C CB    . GLU D 1 32  ? -51.673  -97.207  10.930  1.00 20.19  ? 32   GLU D CB    1 
ATOM   10097 C CG    . GLU D 1 32  ? -51.523  -95.688  11.009  1.00 17.83  ? 32   GLU D CG    1 
ATOM   10098 C CD    . GLU D 1 32  ? -50.397  -95.010  10.199  1.00 21.13  ? 32   GLU D CD    1 
ATOM   10099 O OE1   . GLU D 1 32  ? -49.544  -95.638  9.483   1.00 19.64  ? 32   GLU D OE1   1 
ATOM   10100 O OE2   . GLU D 1 32  ? -50.368  -93.748  10.278  1.00 20.10  ? 32   GLU D OE2   1 
ATOM   10101 N N     . TRP D 1 33  ? -53.578  -96.213  8.214   1.00 25.67  ? 33   TRP D N     1 
ATOM   10102 C CA    . TRP D 1 33  ? -54.844  -95.638  7.771   1.00 22.87  ? 33   TRP D CA    1 
ATOM   10103 C C     . TRP D 1 33  ? -55.502  -96.449  6.651   1.00 22.76  ? 33   TRP D C     1 
ATOM   10104 O O     . TRP D 1 33  ? -56.437  -95.952  6.025   1.00 23.20  ? 33   TRP D O     1 
ATOM   10105 C CB    . TRP D 1 33  ? -54.650  -94.191  7.310   1.00 20.41  ? 33   TRP D CB    1 
ATOM   10106 C CG    . TRP D 1 33  ? -54.600  -93.168  8.417   1.00 21.75  ? 33   TRP D CG    1 
ATOM   10107 C CD1   . TRP D 1 33  ? -53.613  -93.010  9.352   1.00 22.41  ? 33   TRP D CD1   1 
ATOM   10108 C CD2   . TRP D 1 33  ? -55.531  -92.077  8.629   1.00 20.85  ? 33   TRP D CD2   1 
ATOM   10109 N NE1   . TRP D 1 33  ? -53.886  -91.936  10.179  1.00 21.83  ? 33   TRP D NE1   1 
ATOM   10110 C CE2   . TRP D 1 33  ? -55.053  -91.339  9.751   1.00 23.60  ? 33   TRP D CE2   1 
ATOM   10111 C CE3   . TRP D 1 33  ? -56.706  -91.644  7.985   1.00 20.86  ? 33   TRP D CE3   1 
ATOM   10112 C CZ2   . TRP D 1 33  ? -55.719  -90.206  10.239  1.00 23.89  ? 33   TRP D CZ2   1 
ATOM   10113 C CZ3   . TRP D 1 33  ? -57.354  -90.513  8.474   1.00 24.34  ? 33   TRP D CZ3   1 
ATOM   10114 C CH2   . TRP D 1 33  ? -56.858  -89.788  9.578   1.00 21.83  ? 33   TRP D CH2   1 
ATOM   10115 N N     . THR D 1 34  ? -55.044  -97.687  6.394   1.00 22.01  ? 34   THR D N     1 
ATOM   10116 C CA    . THR D 1 34  ? -55.466  -98.403  5.192   1.00 22.34  ? 34   THR D CA    1 
ATOM   10117 C C     . THR D 1 34  ? -57.002  -98.529  5.100   1.00 25.46  ? 34   THR D C     1 
ATOM   10118 O O     . THR D 1 34  ? -57.584  -98.376  4.025   1.00 26.76  ? 34   THR D O     1 
ATOM   10119 C CB    . THR D 1 34  ? -54.751  -99.753  5.084   1.00 19.64  ? 34   THR D CB    1 
ATOM   10120 O OG1   . THR D 1 34  ? -55.241  -100.326 3.876   1.00 18.92  ? 34   THR D OG1   1 
ATOM   10121 C CG2   . THR D 1 34  ? -55.093  -100.728 6.208   1.00 19.79  ? 34   THR D CG2   1 
ATOM   10122 N N     . GLU D 1 35  ? -57.678  -98.792  6.224   1.00 26.17  ? 35   GLU D N     1 
ATOM   10123 C CA    . GLU D 1 35  ? -59.109  -99.038  6.206   1.00 28.44  ? 35   GLU D CA    1 
ATOM   10124 C C     . GLU D 1 35  ? -59.854  -97.854  5.583   1.00 26.01  ? 35   GLU D C     1 
ATOM   10125 O O     . GLU D 1 35  ? -60.694  -98.054  4.698   1.00 26.07  ? 35   GLU D O     1 
ATOM   10126 C CB    . GLU D 1 35  ? -59.719  -99.443  7.551   1.00 28.18  ? 35   GLU D CB    1 
ATOM   10127 C CG    . GLU D 1 35  ? -61.210  -99.740  7.426   1.00 30.46  ? 35   GLU D CG    1 
ATOM   10128 C CD    . GLU D 1 35  ? -61.873  -100.077 8.761   1.00 35.70  ? 35   GLU D CD    1 
ATOM   10129 O OE1   . GLU D 1 35  ? -61.347  -99.731  9.842   1.00 29.79  ? 35   GLU D OE1   1 
ATOM   10130 O OE2   . GLU D 1 35  ? -62.920  -100.741 8.715   1.00 31.92  ? 35   GLU D OE2   1 
ATOM   10131 N N     . LEU D 1 36  ? -59.548  -96.633  6.038   1.00 25.38  ? 36   LEU D N     1 
ATOM   10132 C CA    . LEU D 1 36  ? -60.211  -95.458  5.503   1.00 25.27  ? 36   LEU D CA    1 
ATOM   10133 C C     . LEU D 1 36  ? -59.664  -95.109  4.119   1.00 30.72  ? 36   LEU D C     1 
ATOM   10134 O O     . LEU D 1 36  ? -60.431  -94.948  3.179   1.00 34.74  ? 36   LEU D O     1 
ATOM   10135 C CB    . LEU D 1 36  ? -60.113  -94.275  6.461   1.00 26.92  ? 36   LEU D CB    1 
ATOM   10136 C CG    . LEU D 1 36  ? -60.818  -92.984  6.023   1.00 30.37  ? 36   LEU D CG    1 
ATOM   10137 C CD1   . LEU D 1 36  ? -62.294  -93.278  6.094   1.00 41.41  ? 36   LEU D CD1   1 
ATOM   10138 C CD2   . LEU D 1 36  ? -60.601  -91.877  6.975   1.00 33.67  ? 36   LEU D CD2   1 
ATOM   10139 N N     . ILE D 1 37  ? -58.333  -94.993  3.976   1.00 29.36  ? 37   ILE D N     1 
ATOM   10140 C CA    . ILE D 1 37  ? -57.791  -94.372  2.774   1.00 24.62  ? 37   ILE D CA    1 
ATOM   10141 C C     . ILE D 1 37  ? -57.950  -95.290  1.557   1.00 25.99  ? 37   ILE D C     1 
ATOM   10142 O O     . ILE D 1 37  ? -58.131  -94.799  0.453   1.00 23.39  ? 37   ILE D O     1 
ATOM   10143 C CB    . ILE D 1 37  ? -56.347  -93.890  2.996   1.00 22.60  ? 37   ILE D CB    1 
ATOM   10144 C CG1   . ILE D 1 37  ? -56.360  -92.723  3.981   1.00 20.42  ? 37   ILE D CG1   1 
ATOM   10145 C CG2   . ILE D 1 37  ? -55.679  -93.509  1.661   1.00 19.89  ? 37   ILE D CG2   1 
ATOM   10146 C CD1   . ILE D 1 37  ? -54.967  -92.273  4.386   1.00 26.29  ? 37   ILE D CD1   1 
ATOM   10147 N N     . HIS D 1 38  ? -57.895  -96.614  1.748   1.00 24.78  ? 38   HIS D N     1 
ATOM   10148 C CA    . HIS D 1 38  ? -58.100  -97.522  0.634   1.00 26.02  ? 38   HIS D CA    1 
ATOM   10149 C C     . HIS D 1 38  ? -59.577  -97.916  0.505   1.00 29.97  ? 38   HIS D C     1 
ATOM   10150 O O     . HIS D 1 38  ? -59.862  -98.882  -0.200  1.00 28.15  ? 38   HIS D O     1 
ATOM   10151 C CB    . HIS D 1 38  ? -57.259  -98.796  0.828   1.00 25.30  ? 38   HIS D CB    1 
ATOM   10152 C CG    . HIS D 1 38  ? -55.794  -98.558  0.653   1.00 28.19  ? 38   HIS D CG    1 
ATOM   10153 N ND1   . HIS D 1 38  ? -54.866  -98.972  1.584   1.00 25.32  ? 38   HIS D ND1   1 
ATOM   10154 C CD2   . HIS D 1 38  ? -55.102  -97.879  -0.315  1.00 25.68  ? 38   HIS D CD2   1 
ATOM   10155 C CE1   . HIS D 1 38  ? -53.650  -98.616  1.158   1.00 27.54  ? 38   HIS D CE1   1 
ATOM   10156 N NE2   . HIS D 1 38  ? -53.777  -97.940  0.006   1.00 26.81  ? 38   HIS D NE2   1 
ATOM   10157 N N     . HIS D 1 39  ? -60.486  -97.230  1.233   1.00 30.72  ? 39   HIS D N     1 
ATOM   10158 C CA    . HIS D 1 39  ? -61.933  -97.391  1.091   1.00 37.60  ? 39   HIS D CA    1 
ATOM   10159 C C     . HIS D 1 39  ? -62.323  -98.862  1.239   1.00 31.63  ? 39   HIS D C     1 
ATOM   10160 O O     . HIS D 1 39  ? -63.003  -99.424  0.386   1.00 27.38  ? 39   HIS D O     1 
ATOM   10161 C CB    . HIS D 1 39  ? -62.470  -96.702  -0.190  1.00 44.24  ? 39   HIS D CB    1 
ATOM   10162 C CG    . HIS D 1 39  ? -63.982  -96.595  -0.270  1.00 95.01  ? 39   HIS D CG    1 
ATOM   10163 N ND1   . HIS D 1 39  ? -64.755  -95.779  0.543   1.00 111.02 ? 39   HIS D ND1   1 
ATOM   10164 C CD2   . HIS D 1 39  ? -64.876  -97.241  -1.060  1.00 103.51 ? 39   HIS D CD2   1 
ATOM   10165 C CE1   . HIS D 1 39  ? -66.045  -95.913  0.248   1.00 85.56  ? 39   HIS D CE1   1 
ATOM   10166 N NE2   . HIS D 1 39  ? -66.142  -96.792  -0.728  1.00 97.15  ? 39   HIS D NE2   1 
ATOM   10167 N N     . ARG D 1 40  ? -61.853  -99.528  2.294   1.00 31.19  ? 40   ARG D N     1 
ATOM   10168 C CA    . ARG D 1 40  ? -62.081  -100.966 2.365   1.00 29.42  ? 40   ARG D CA    1 
ATOM   10169 C C     . ARG D 1 40  ? -63.477  -101.234 2.911   1.00 30.80  ? 40   ARG D C     1 
ATOM   10170 O O     . ARG D 1 40  ? -64.044  -100.420 3.634   1.00 33.78  ? 40   ARG D O     1 
ATOM   10171 C CB    . ARG D 1 40  ? -61.057  -101.596 3.305   1.00 29.99  ? 40   ARG D CB    1 
ATOM   10172 C CG    . ARG D 1 40  ? -59.670  -101.608 2.693   1.00 35.09  ? 40   ARG D CG    1 
ATOM   10173 C CD    . ARG D 1 40  ? -58.730  -102.331 3.624   1.00 36.69  ? 40   ARG D CD    1 
ATOM   10174 N NE    . ARG D 1 40  ? -57.315  -102.239 3.252   1.00 45.37  ? 40   ARG D NE    1 
ATOM   10175 C CZ    . ARG D 1 40  ? -56.687  -102.986 2.350   1.00 40.50  ? 40   ARG D CZ    1 
ATOM   10176 N NH1   . ARG D 1 40  ? -57.355  -103.833 1.598   1.00 35.08  ? 40   ARG D NH1   1 
ATOM   10177 N NH2   . ARG D 1 40  ? -55.400  -102.819 2.156   1.00 39.07  ? 40   ARG D NH2   1 
ATOM   10178 N N     . ASN D 1 41  ? -64.028  -102.395 2.559   1.00 34.45  ? 41   ASN D N     1 
ATOM   10179 C CA    . ASN D 1 41  ? -65.236  -102.893 3.188   1.00 33.05  ? 41   ASN D CA    1 
ATOM   10180 C C     . ASN D 1 41  ? -64.977  -103.137 4.684   1.00 32.87  ? 41   ASN D C     1 
ATOM   10181 O O     . ASN D 1 41  ? -64.155  -103.982 5.062   1.00 26.66  ? 41   ASN D O     1 
ATOM   10182 C CB    . ASN D 1 41  ? -65.705  -104.158 2.464   1.00 33.52  ? 41   ASN D CB    1 
ATOM   10183 C CG    . ASN D 1 41  ? -66.933  -104.730 3.132   1.00 36.22  ? 41   ASN D CG    1 
ATOM   10184 O OD1   . ASN D 1 41  ? -66.840  -105.535 4.078   1.00 41.47  ? 41   ASN D OD1   1 
ATOM   10185 N ND2   . ASN D 1 41  ? -68.074  -104.226 2.703   1.00 34.51  ? 41   ASN D ND2   1 
ATOM   10186 N N     . GLN D 1 42  ? -65.735  -102.448 5.543   1.00 30.82  ? 42   GLN D N     1 
ATOM   10187 C CA    . GLN D 1 42  ? -65.512  -102.545 6.979   1.00 31.45  ? 42   GLN D CA    1 
ATOM   10188 C C     . GLN D 1 42  ? -65.585  -103.994 7.477   1.00 31.77  ? 42   GLN D C     1 
ATOM   10189 O O     . GLN D 1 42  ? -64.727  -104.443 8.241   1.00 31.42  ? 42   GLN D O     1 
ATOM   10190 C CB    . GLN D 1 42  ? -66.434  -101.613 7.762   1.00 27.95  ? 42   GLN D CB    1 
ATOM   10191 C CG    . GLN D 1 42  ? -66.182  -101.724 9.257   1.00 40.04  ? 42   GLN D CG    1 
ATOM   10192 C CD    . GLN D 1 42  ? -66.922  -100.674 10.055  1.00 44.16  ? 42   GLN D CD    1 
ATOM   10193 O OE1   . GLN D 1 42  ? -66.747  -100.558 11.259  1.00 52.14  ? 42   GLN D OE1   1 
ATOM   10194 N NE2   . GLN D 1 42  ? -67.816  -99.934  9.426   1.00 44.28  ? 42   GLN D NE2   1 
ATOM   10195 N N     . HIS D 1 43  ? -66.622  -104.723 7.050   1.00 35.58  ? 43   HIS D N     1 
ATOM   10196 C CA    . HIS D 1 43  ? -66.832  -106.088 7.521   1.00 33.11  ? 43   HIS D CA    1 
ATOM   10197 C C     . HIS D 1 43  ? -65.609  -106.937 7.166   1.00 29.63  ? 43   HIS D C     1 
ATOM   10198 O O     . HIS D 1 43  ? -65.156  -107.742 7.972   1.00 34.10  ? 43   HIS D O     1 
ATOM   10199 C CB    . HIS D 1 43  ? -68.185  -106.644 7.030   1.00 33.80  ? 43   HIS D CB    1 
ATOM   10200 C CG    . HIS D 1 43  ? -68.300  -108.125 7.249   1.00 42.45  ? 43   HIS D CG    1 
ATOM   10201 N ND1   . HIS D 1 43  ? -68.872  -108.652 8.398   1.00 41.70  ? 43   HIS D ND1   1 
ATOM   10202 C CD2   . HIS D 1 43  ? -67.832  -109.206 6.516   1.00 36.82  ? 43   HIS D CD2   1 
ATOM   10203 C CE1   . HIS D 1 43  ? -68.796  -109.987 8.361   1.00 38.01  ? 43   HIS D CE1   1 
ATOM   10204 N NE2   . HIS D 1 43  ? -68.150  -110.342 7.241   1.00 40.41  ? 43   HIS D NE2   1 
ATOM   10205 N N     . ASP D 1 44  ? -65.106  -106.788 5.939   1.00 28.93  ? 44   ASP D N     1 
ATOM   10206 C CA    . ASP D 1 44  ? -64.002  -107.616 5.451   1.00 33.52  ? 44   ASP D CA    1 
ATOM   10207 C C     . ASP D 1 44  ? -62.710  -107.269 6.187   1.00 31.75  ? 44   ASP D C     1 
ATOM   10208 O O     . ASP D 1 44  ? -62.007  -108.161 6.630   1.00 31.30  ? 44   ASP D O     1 
ATOM   10209 C CB    . ASP D 1 44  ? -63.857  -107.559 3.937   1.00 37.40  ? 44   ASP D CB    1 
ATOM   10210 C CG    . ASP D 1 44  ? -65.065  -108.097 3.163   1.00 44.67  ? 44   ASP D CG    1 
ATOM   10211 O OD1   . ASP D 1 44  ? -65.929  -108.780 3.761   1.00 46.47  ? 44   ASP D OD1   1 
ATOM   10212 O OD2   . ASP D 1 44  ? -65.195  -107.756 1.980   1.00 44.72  ? 44   ASP D OD2   1 
ATOM   10213 N N     . TYR D 1 45  ? -62.442  -105.970 6.372   1.00 30.08  ? 45   TYR D N     1 
ATOM   10214 C CA    . TYR D 1 45  ? -61.272  -105.516 7.102   1.00 27.02  ? 45   TYR D CA    1 
ATOM   10215 C C     . TYR D 1 45  ? -61.291  -106.059 8.536   1.00 26.37  ? 45   TYR D C     1 
ATOM   10216 O O     . TYR D 1 45  ? -60.288  -106.587 8.997   1.00 28.04  ? 45   TYR D O     1 
ATOM   10217 C CB    . TYR D 1 45  ? -61.194  -103.990 7.015   1.00 24.70  ? 45   TYR D CB    1 
ATOM   10218 C CG    . TYR D 1 45  ? -60.016  -103.437 7.798   1.00 25.91  ? 45   TYR D CG    1 
ATOM   10219 C CD1   . TYR D 1 45  ? -58.743  -103.356 7.223   1.00 27.28  ? 45   TYR D CD1   1 
ATOM   10220 C CD2   . TYR D 1 45  ? -60.172  -102.999 9.109   1.00 22.87  ? 45   TYR D CD2   1 
ATOM   10221 C CE1   . TYR D 1 45  ? -57.654  -102.836 7.927   1.00 24.76  ? 45   TYR D CE1   1 
ATOM   10222 C CE2   . TYR D 1 45  ? -59.102  -102.485 9.822   1.00 23.02  ? 45   TYR D CE2   1 
ATOM   10223 C CZ    . TYR D 1 45  ? -57.843  -102.411 9.237   1.00 25.25  ? 45   TYR D CZ    1 
ATOM   10224 O OH    . TYR D 1 45  ? -56.814  -101.870 9.946   1.00 23.36  ? 45   TYR D OH    1 
ATOM   10225 N N     . GLU D 1 46  ? -62.445  -105.986 9.216   1.00 26.45  ? 46   GLU D N     1 
ATOM   10226 C CA    . GLU D 1 46  ? -62.561  -106.396 10.609  1.00 24.46  ? 46   GLU D CA    1 
ATOM   10227 C C     . GLU D 1 46  ? -62.355  -107.897 10.812  1.00 26.51  ? 46   GLU D C     1 
ATOM   10228 O O     . GLU D 1 46  ? -62.065  -108.340 11.926  1.00 29.05  ? 46   GLU D O     1 
ATOM   10229 C CB    . GLU D 1 46  ? -63.787  -105.792 11.291  1.00 22.31  ? 46   GLU D CB    1 
ATOM   10230 C CG    . GLU D 1 46  ? -63.715  -104.266 11.285  1.00 26.12  ? 46   GLU D CG    1 
ATOM   10231 C CD    . GLU D 1 46  ? -64.800  -103.606 12.121  1.00 35.53  ? 46   GLU D CD    1 
ATOM   10232 O OE1   . GLU D 1 46  ? -65.731  -104.329 12.510  1.00 40.61  ? 46   GLU D OE1   1 
ATOM   10233 O OE2   . GLU D 1 46  ? -64.740  -102.382 12.396  1.00 33.37  ? 46   GLU D OE2   1 
ATOM   10234 N N     . GLN D 1 47  ? -62.444  -108.679 9.735   1.00 26.53  ? 47   GLN D N     1 
ATOM   10235 C CA    . GLN D 1 47  ? -62.141  -110.109 9.806   1.00 29.02  ? 47   GLN D CA    1 
ATOM   10236 C C     . GLN D 1 47  ? -60.666  -110.363 10.153  1.00 32.49  ? 47   GLN D C     1 
ATOM   10237 O O     . GLN D 1 47  ? -60.298  -111.474 10.521  1.00 31.28  ? 47   GLN D O     1 
ATOM   10238 C CB    . GLN D 1 47  ? -62.425  -110.800 8.467   1.00 35.26  ? 47   GLN D CB    1 
ATOM   10239 C CG    . GLN D 1 47  ? -63.904  -110.860 8.075   1.00 42.03  ? 47   GLN D CG    1 
ATOM   10240 C CD    . GLN D 1 47  ? -64.721  -111.674 9.052   1.00 47.88  ? 47   GLN D CD    1 
ATOM   10241 O OE1   . GLN D 1 47  ? -64.585  -112.910 9.122   1.00 45.85  ? 47   GLN D OE1   1 
ATOM   10242 N NE2   . GLN D 1 47  ? -65.531  -110.961 9.831   1.00 39.92  ? 47   GLN D NE2   1 
ATOM   10243 N N     . LEU D 1 48  ? -59.800  -109.347 10.007  1.00 27.34  ? 48   LEU D N     1 
ATOM   10244 C CA    . LEU D 1 48  ? -58.394  -109.458 10.367  1.00 23.93  ? 48   LEU D CA    1 
ATOM   10245 C C     . LEU D 1 48  ? -58.239  -109.840 11.835  1.00 24.22  ? 48   LEU D C     1 
ATOM   10246 O O     . LEU D 1 48  ? -57.183  -110.368 12.212  1.00 24.77  ? 48   LEU D O     1 
ATOM   10247 C CB    . LEU D 1 48  ? -57.630  -108.172 10.039  1.00 23.69  ? 48   LEU D CB    1 
ATOM   10248 C CG    . LEU D 1 48  ? -57.424  -107.895 8.540   1.00 22.77  ? 48   LEU D CG    1 
ATOM   10249 C CD1   . LEU D 1 48  ? -56.828  -106.513 8.339   1.00 17.35  ? 48   LEU D CD1   1 
ATOM   10250 C CD2   . LEU D 1 48  ? -56.554  -109.022 7.909   1.00 19.75  ? 48   LEU D CD2   1 
ATOM   10251 N N     . ILE D 1 49  ? -59.273  -109.591 12.672  1.00 23.53  ? 49   ILE D N     1 
ATOM   10252 C CA    . ILE D 1 49  ? -59.214  -110.072 14.051  1.00 24.19  ? 49   ILE D CA    1 
ATOM   10253 C C     . ILE D 1 49  ? -58.959  -111.583 14.115  1.00 28.10  ? 49   ILE D C     1 
ATOM   10254 O O     . ILE D 1 49  ? -58.295  -112.059 15.050  1.00 27.82  ? 49   ILE D O     1 
ATOM   10255 C CB    . ILE D 1 49  ? -60.459  -109.674 14.875  1.00 30.86  ? 49   ILE D CB    1 
ATOM   10256 C CG1   . ILE D 1 49  ? -60.208  -109.870 16.377  1.00 26.31  ? 49   ILE D CG1   1 
ATOM   10257 C CG2   . ILE D 1 49  ? -61.740  -110.392 14.415  1.00 21.88  ? 49   ILE D CG2   1 
ATOM   10258 C CD1   . ILE D 1 49  ? -61.255  -109.219 17.248  1.00 22.45  ? 49   ILE D CD1   1 
ATOM   10259 N N     . LYS D 1 50  ? -59.452  -112.342 13.115  1.00 29.58  ? 50   LYS D N     1 
ATOM   10260 C CA    . LYS D 1 50  ? -59.388  -113.798 13.187  1.00 29.17  ? 50   LYS D CA    1 
ATOM   10261 C C     . LYS D 1 50  ? -57.962  -114.305 12.992  1.00 31.38  ? 50   LYS D C     1 
ATOM   10262 O O     . LYS D 1 50  ? -57.671  -115.434 13.365  1.00 33.95  ? 50   LYS D O     1 
ATOM   10263 C CB    . LYS D 1 50  ? -60.291  -114.475 12.148  1.00 27.38  ? 50   LYS D CB    1 
ATOM   10264 C CG    . LYS D 1 50  ? -61.733  -114.298 12.482  1.00 34.95  ? 50   LYS D CG    1 
ATOM   10265 C CD    . LYS D 1 50  ? -62.677  -114.749 11.387  1.00 42.74  ? 50   LYS D CD    1 
ATOM   10266 C CE    . LYS D 1 50  ? -64.014  -114.749 12.089  1.00 58.05  ? 50   LYS D CE    1 
ATOM   10267 N NZ    . LYS D 1 50  ? -65.089  -115.045 11.144  1.00 65.05  ? 50   LYS D NZ    1 
ATOM   10268 N N     . THR D 1 51  ? -57.082  -113.486 12.399  1.00 27.58  ? 51   THR D N     1 
ATOM   10269 C CA    . THR D 1 51  ? -55.714  -113.910 12.156  1.00 27.95  ? 51   THR D CA    1 
ATOM   10270 C C     . THR D 1 51  ? -54.744  -113.098 13.028  1.00 28.13  ? 51   THR D C     1 
ATOM   10271 O O     . THR D 1 51  ? -53.536  -113.134 12.802  1.00 32.09  ? 51   THR D O     1 
ATOM   10272 C CB    . THR D 1 51  ? -55.384  -113.847 10.654  1.00 28.11  ? 51   THR D CB    1 
ATOM   10273 O OG1   . THR D 1 51  ? -55.955  -112.611 10.210  1.00 26.88  ? 51   THR D OG1   1 
ATOM   10274 C CG2   . THR D 1 51  ? -56.040  -114.969 9.856   1.00 23.94  ? 51   THR D CG2   1 
ATOM   10275 N N     . PHE D 1 52  ? -55.259  -112.367 14.022  1.00 24.69  ? 52   PHE D N     1 
ATOM   10276 C CA    . PHE D 1 52  ? -54.404  -111.628 14.942  1.00 24.23  ? 52   PHE D CA    1 
ATOM   10277 C C     . PHE D 1 52  ? -53.919  -112.566 16.049  1.00 25.59  ? 52   PHE D C     1 
ATOM   10278 O O     . PHE D 1 52  ? -54.550  -112.649 17.107  1.00 28.63  ? 52   PHE D O     1 
ATOM   10279 C CB    . PHE D 1 52  ? -55.147  -110.422 15.524  1.00 23.04  ? 52   PHE D CB    1 
ATOM   10280 C CG    . PHE D 1 52  ? -54.280  -109.482 16.366  1.00 28.16  ? 52   PHE D CG    1 
ATOM   10281 C CD1   . PHE D 1 52  ? -53.443  -108.528 15.770  1.00 29.76  ? 52   PHE D CD1   1 
ATOM   10282 C CD2   . PHE D 1 52  ? -54.310  -109.536 17.762  1.00 28.73  ? 52   PHE D CD2   1 
ATOM   10283 C CE1   . PHE D 1 52  ? -52.678  -107.648 16.548  1.00 26.02  ? 52   PHE D CE1   1 
ATOM   10284 C CE2   . PHE D 1 52  ? -53.530  -108.658 18.530  1.00 28.12  ? 52   PHE D CE2   1 
ATOM   10285 C CZ    . PHE D 1 52  ? -52.709  -107.723 17.925  1.00 22.27  ? 52   PHE D CZ    1 
ATOM   10286 N N     . THR D 1 53  ? -52.800  -113.259 15.811  1.00 24.73  ? 53   THR D N     1 
ATOM   10287 C CA    . THR D 1 53  ? -52.303  -114.288 16.726  1.00 26.98  ? 53   THR D CA    1 
ATOM   10288 C C     . THR D 1 53  ? -51.316  -113.703 17.732  1.00 28.32  ? 53   THR D C     1 
ATOM   10289 O O     . THR D 1 53  ? -51.064  -114.309 18.760  1.00 28.69  ? 53   THR D O     1 
ATOM   10290 C CB    . THR D 1 53  ? -51.619  -115.416 15.951  1.00 27.54  ? 53   THR D CB    1 
ATOM   10291 O OG1   . THR D 1 53  ? -50.516  -114.736 15.337  1.00 29.11  ? 53   THR D OG1   1 
ATOM   10292 C CG2   . THR D 1 53  ? -52.533  -116.094 14.930  1.00 25.11  ? 53   THR D CG2   1 
ATOM   10293 N N     . ALA D 1 54  ? -50.693  -112.574 17.398  1.00 29.40  ? 54   ALA D N     1 
ATOM   10294 C CA    . ALA D 1 54  ? -49.581  -112.020 18.163  1.00 27.91  ? 54   ALA D CA    1 
ATOM   10295 C C     . ALA D 1 54  ? -48.472  -113.046 18.346  1.00 29.92  ? 54   ALA D C     1 
ATOM   10296 O O     . ALA D 1 54  ? -47.766  -112.976 19.350  1.00 27.61  ? 54   ALA D O     1 
ATOM   10297 C CB    . ALA D 1 54  ? -50.038  -111.510 19.516  1.00 25.61  ? 54   ALA D CB    1 
ATOM   10298 N N     . ALA D 1 55  ? -48.311  -113.965 17.384  1.00 27.73  ? 55   ALA D N     1 
ATOM   10299 C CA    . ALA D 1 55  ? -47.395  -115.089 17.557  1.00 25.75  ? 55   ALA D CA    1 
ATOM   10300 C C     . ALA D 1 55  ? -45.940  -114.636 17.717  1.00 27.32  ? 55   ALA D C     1 
ATOM   10301 O O     . ALA D 1 55  ? -45.119  -115.372 18.246  1.00 24.54  ? 55   ALA D O     1 
ATOM   10302 C CB    . ALA D 1 55  ? -47.532  -116.083 16.405  1.00 25.12  ? 55   ALA D CB    1 
ATOM   10303 N N     . GLN D 1 56  ? -45.573  -113.433 17.272  1.00 30.68  ? 56   GLN D N     1 
ATOM   10304 C CA    . GLN D 1 56  ? -44.178  -113.036 17.421  1.00 26.39  ? 56   GLN D CA    1 
ATOM   10305 C C     . GLN D 1 56  ? -44.032  -111.811 18.312  1.00 27.60  ? 56   GLN D C     1 
ATOM   10306 O O     . GLN D 1 56  ? -42.989  -111.180 18.328  1.00 31.60  ? 56   GLN D O     1 
ATOM   10307 C CB    . GLN D 1 56  ? -43.523  -112.801 16.069  1.00 30.06  ? 56   GLN D CB    1 
ATOM   10308 C CG    . GLN D 1 56  ? -42.994  -114.076 15.439  1.00 35.39  ? 56   GLN D CG    1 
ATOM   10309 C CD    . GLN D 1 56  ? -43.294  -114.062 13.970  1.00 45.42  ? 56   GLN D CD    1 
ATOM   10310 O OE1   . GLN D 1 56  ? -44.325  -114.594 13.564  1.00 73.43  ? 56   GLN D OE1   1 
ATOM   10311 N NE2   . GLN D 1 56  ? -42.486  -113.382 13.172  1.00 47.16  ? 56   GLN D NE2   1 
ATOM   10312 N N     . PHE D 1 57  ? -45.078  -111.473 19.059  1.00 27.06  ? 57   PHE D N     1 
ATOM   10313 C CA    . PHE D 1 57  ? -44.976  -110.331 19.938  1.00 23.97  ? 57   PHE D CA    1 
ATOM   10314 C C     . PHE D 1 57  ? -44.289  -110.773 21.219  1.00 26.55  ? 57   PHE D C     1 
ATOM   10315 O O     . PHE D 1 57  ? -44.784  -111.638 21.928  1.00 26.51  ? 57   PHE D O     1 
ATOM   10316 C CB    . PHE D 1 57  ? -46.353  -109.764 20.252  1.00 21.98  ? 57   PHE D CB    1 
ATOM   10317 C CG    . PHE D 1 57  ? -46.310  -108.578 21.201  1.00 25.55  ? 57   PHE D CG    1 
ATOM   10318 C CD1   . PHE D 1 57  ? -45.853  -107.332 20.767  1.00 24.20  ? 57   PHE D CD1   1 
ATOM   10319 C CD2   . PHE D 1 57  ? -46.762  -108.702 22.508  1.00 23.90  ? 57   PHE D CD2   1 
ATOM   10320 C CE1   . PHE D 1 57  ? -45.833  -106.245 21.637  1.00 24.73  ? 57   PHE D CE1   1 
ATOM   10321 C CE2   . PHE D 1 57  ? -46.767  -107.597 23.356  1.00 25.54  ? 57   PHE D CE2   1 
ATOM   10322 C CZ    . PHE D 1 57  ? -46.295  -106.368 22.922  1.00 25.42  ? 57   PHE D CZ    1 
ATOM   10323 N N     . ASP D 1 58  ? -43.163  -110.138 21.518  1.00 27.29  ? 58   ASP D N     1 
ATOM   10324 C CA    . ASP D 1 58  ? -42.488  -110.360 22.778  1.00 27.90  ? 58   ASP D CA    1 
ATOM   10325 C C     . ASP D 1 58  ? -42.248  -109.004 23.446  1.00 26.78  ? 58   ASP D C     1 
ATOM   10326 O O     . ASP D 1 58  ? -41.365  -108.234 23.029  1.00 26.58  ? 58   ASP D O     1 
ATOM   10327 C CB    . ASP D 1 58  ? -41.216  -111.156 22.506  1.00 30.60  ? 58   ASP D CB    1 
ATOM   10328 C CG    . ASP D 1 58  ? -40.428  -111.557 23.748  1.00 40.88  ? 58   ASP D CG    1 
ATOM   10329 O OD1   . ASP D 1 58  ? -40.762  -111.090 24.863  1.00 38.98  ? 58   ASP D OD1   1 
ATOM   10330 O OD2   . ASP D 1 58  ? -39.467  -112.330 23.624  1.00 47.81  ? 58   ASP D OD2   1 
ATOM   10331 N N     . ALA D 1 59  ? -43.032  -108.693 24.474  1.00 24.25  ? 59   ALA D N     1 
ATOM   10332 C CA    . ALA D 1 59  ? -42.943  -107.377 25.094  1.00 25.83  ? 59   ALA D CA    1 
ATOM   10333 C C     . ALA D 1 59  ? -41.551  -107.160 25.700  1.00 26.65  ? 59   ALA D C     1 
ATOM   10334 O O     . ALA D 1 59  ? -41.072  -106.037 25.785  1.00 22.83  ? 59   ALA D O     1 
ATOM   10335 C CB    . ALA D 1 59  ? -44.043  -107.209 26.123  1.00 21.07  ? 59   ALA D CB    1 
ATOM   10336 N N     . LYS D 1 60  ? -40.903  -108.245 26.127  1.00 28.49  ? 60   LYS D N     1 
ATOM   10337 C CA    . LYS D 1 60  ? -39.565  -108.149 26.694  1.00 31.30  ? 60   LYS D CA    1 
ATOM   10338 C C     . LYS D 1 60  ? -38.585  -107.737 25.594  1.00 27.07  ? 60   LYS D C     1 
ATOM   10339 O O     . LYS D 1 60  ? -37.718  -106.944 25.865  1.00 24.48  ? 60   LYS D O     1 
ATOM   10340 C CB    . LYS D 1 60  ? -39.048  -109.426 27.374  1.00 31.78  ? 60   LYS D CB    1 
ATOM   10341 C CG    . LYS D 1 60  ? -39.778  -109.826 28.628  1.00 41.48  ? 60   LYS D CG    1 
ATOM   10342 C CD    . LYS D 1 60  ? -39.047  -110.886 29.458  1.00 58.45  ? 60   LYS D CD    1 
ATOM   10343 C CE    . LYS D 1 60  ? -39.986  -111.619 30.399  1.00 74.58  ? 60   LYS D CE    1 
ATOM   10344 N NZ    . LYS D 1 60  ? -40.838  -110.743 31.219  1.00 75.16  ? 60   LYS D NZ    1 
ATOM   10345 N N     . LYS D 1 61  ? -38.712  -108.246 24.368  1.00 26.61  ? 61   LYS D N     1 
ATOM   10346 C CA    . LYS D 1 61  ? -37.832  -107.823 23.282  1.00 29.73  ? 61   LYS D CA    1 
ATOM   10347 C C     . LYS D 1 61  ? -38.060  -106.341 22.957  1.00 32.09  ? 61   LYS D C     1 
ATOM   10348 O O     . LYS D 1 61  ? -37.130  -105.588 22.700  1.00 31.23  ? 61   LYS D O     1 
ATOM   10349 C CB    . LYS D 1 61  ? -37.950  -108.682 22.016  1.00 34.74  ? 61   LYS D CB    1 
ATOM   10350 C CG    . LYS D 1 61  ? -37.312  -110.049 22.028  1.00 39.18  ? 61   LYS D CG    1 
ATOM   10351 C CD    . LYS D 1 61  ? -37.539  -110.679 20.658  1.00 51.53  ? 61   LYS D CD    1 
ATOM   10352 C CE    . LYS D 1 61  ? -37.645  -112.157 20.878  1.00 58.78  ? 61   LYS D CE    1 
ATOM   10353 N NZ    . LYS D 1 61  ? -37.772  -112.918 19.643  1.00 54.95  ? 61   LYS D NZ    1 
ATOM   10354 N N     . ILE D 1 62  ? -39.310  -105.887 22.997  1.00 30.41  ? 62   ILE D N     1 
ATOM   10355 C CA    . ILE D 1 62  ? -39.582  -104.487 22.741  1.00 27.81  ? 62   ILE D CA    1 
ATOM   10356 C C     . ILE D 1 62  ? -38.979  -103.592 23.824  1.00 25.42  ? 62   ILE D C     1 
ATOM   10357 O O     . ILE D 1 62  ? -38.337  -102.580 23.523  1.00 28.65  ? 62   ILE D O     1 
ATOM   10358 C CB    . ILE D 1 62  ? -41.091  -104.306 22.531  1.00 30.15  ? 62   ILE D CB    1 
ATOM   10359 C CG1   . ILE D 1 62  ? -41.437  -104.844 21.160  1.00 31.97  ? 62   ILE D CG1   1 
ATOM   10360 C CG2   . ILE D 1 62  ? -41.513  -102.843 22.680  1.00 26.11  ? 62   ILE D CG2   1 
ATOM   10361 C CD1   . ILE D 1 62  ? -42.884  -105.108 21.017  1.00 36.92  ? 62   ILE D CD1   1 
ATOM   10362 N N     . ALA D 1 63  ? -39.128  -103.999 25.076  1.00 21.54  ? 63   ALA D N     1 
ATOM   10363 C CA    . ALA D 1 63  ? -38.552  -103.240 26.181  1.00 22.54  ? 63   ALA D CA    1 
ATOM   10364 C C     . ALA D 1 63  ? -37.019  -103.218 26.081  1.00 23.73  ? 63   ALA D C     1 
ATOM   10365 O O     . ALA D 1 63  ? -36.398  -102.182 26.303  1.00 19.94  ? 63   ALA D O     1 
ATOM   10366 C CB    . ALA D 1 63  ? -39.058  -103.764 27.522  1.00 18.05  ? 63   ALA D CB    1 
ATOM   10367 N N     . HIS D 1 64  ? -36.425  -104.347 25.691  1.00 21.62  ? 64   HIS D N     1 
ATOM   10368 C CA    . HIS D 1 64  ? -34.987  -104.464 25.519  1.00 27.35  ? 64   HIS D CA    1 
ATOM   10369 C C     . HIS D 1 64  ? -34.518  -103.485 24.444  1.00 28.57  ? 64   HIS D C     1 
ATOM   10370 O O     . HIS D 1 64  ? -33.544  -102.752 24.654  1.00 26.57  ? 64   HIS D O     1 
ATOM   10371 C CB    . HIS D 1 64  ? -34.534  -105.932 25.316  1.00 26.96  ? 64   HIS D CB    1 
ATOM   10372 C CG    . HIS D 1 64  ? -33.121  -106.071 24.820  1.00 33.46  ? 64   HIS D CG    1 
ATOM   10373 N ND1   . HIS D 1 64  ? -32.001  -105.904 25.628  1.00 35.33  ? 64   HIS D ND1   1 
ATOM   10374 C CD2   . HIS D 1 64  ? -32.661  -106.142 23.547  1.00 34.67  ? 64   HIS D CD2   1 
ATOM   10375 C CE1   . HIS D 1 64  ? -30.907  -105.980 24.875  1.00 32.45  ? 64   HIS D CE1   1 
ATOM   10376 N NE2   . HIS D 1 64  ? -31.283  -106.106 23.608  1.00 38.33  ? 64   HIS D NE2   1 
ATOM   10377 N N     . ALA D 1 65  ? -35.199  -103.485 23.297  1.00 25.11  ? 65   ALA D N     1 
ATOM   10378 C CA    . ALA D 1 65  ? -34.846  -102.599 22.197  1.00 24.08  ? 65   ALA D CA    1 
ATOM   10379 C C     . ALA D 1 65  ? -34.907  -101.135 22.656  1.00 25.02  ? 65   ALA D C     1 
ATOM   10380 O O     . ALA D 1 65  ? -33.975  -100.362 22.365  1.00 27.16  ? 65   ALA D O     1 
ATOM   10381 C CB    . ALA D 1 65  ? -35.747  -102.833 20.990  1.00 23.18  ? 65   ALA D CB    1 
ATOM   10382 N N     . ALA D 1 66  ? -35.965  -100.776 23.421  1.00 21.47  ? 66   ALA D N     1 
ATOM   10383 C CA    . ALA D 1 66  ? -36.062  -99.419  23.911  1.00 21.49  ? 66   ALA D CA    1 
ATOM   10384 C C     . ALA D 1 66  ? -34.880  -99.059  24.815  1.00 24.83  ? 66   ALA D C     1 
ATOM   10385 O O     . ALA D 1 66  ? -34.319  -97.964  24.721  1.00 20.98  ? 66   ALA D O     1 
ATOM   10386 C CB    . ALA D 1 66  ? -37.381  -99.245  24.604  1.00 18.39  ? 66   ALA D CB    1 
ATOM   10387 N N     . LYS D 1 67  ? -34.519  -99.989  25.706  1.00 25.34  ? 67   LYS D N     1 
ATOM   10388 C CA    . LYS D 1 67  ? -33.426  -99.768  26.639  1.00 26.05  ? 67   LYS D CA    1 
ATOM   10389 C C     . LYS D 1 67  ? -32.116  -99.568  25.860  1.00 23.78  ? 67   LYS D C     1 
ATOM   10390 O O     . LYS D 1 67  ? -31.392  -98.615  26.125  1.00 27.19  ? 67   LYS D O     1 
ATOM   10391 C CB    . LYS D 1 67  ? -33.326  -100.891 27.682  1.00 23.37  ? 67   LYS D CB    1 
ATOM   10392 C CG    . LYS D 1 67  ? -32.439  -100.438 28.814  1.00 27.52  ? 67   LYS D CG    1 
ATOM   10393 C CD    . LYS D 1 67  ? -33.304  -99.835  29.921  1.00 25.18  ? 67   LYS D CD    1 
ATOM   10394 C CE    . LYS D 1 67  ? -32.416  -99.448  31.055  1.00 26.95  ? 67   LYS D CE    1 
ATOM   10395 N NZ    . LYS D 1 67  ? -33.200  -98.652  31.993  1.00 32.74  ? 67   LYS D NZ    1 
ATOM   10396 N N     . ALA D 1 68  ? -31.849  -100.435 24.880  1.00 20.03  ? 68   ALA D N     1 
ATOM   10397 C CA    . ALA D 1 68  ? -30.621  -100.394 24.092  1.00 24.22  ? 68   ALA D CA    1 
ATOM   10398 C C     . ALA D 1 68  ? -30.518  -99.077  23.307  1.00 29.13  ? 68   ALA D C     1 
ATOM   10399 O O     . ALA D 1 68  ? -29.427  -98.568  23.112  1.00 31.94  ? 68   ALA D O     1 
ATOM   10400 C CB    . ALA D 1 68  ? -30.545  -101.597 23.139  1.00 18.50  ? 68   ALA D CB    1 
ATOM   10401 N N     . VAL D 1 69  ? -31.648  -98.529  22.860  1.00 26.35  ? 69   VAL D N     1 
ATOM   10402 C CA    . VAL D 1 69  ? -31.594  -97.343  22.030  1.00 24.67  ? 69   VAL D CA    1 
ATOM   10403 C C     . VAL D 1 69  ? -31.475  -96.101  22.925  1.00 26.35  ? 69   VAL D C     1 
ATOM   10404 O O     . VAL D 1 69  ? -31.311  -94.992  22.399  1.00 24.35  ? 69   VAL D O     1 
ATOM   10405 C CB    . VAL D 1 69  ? -32.799  -97.253  21.066  1.00 24.27  ? 69   VAL D CB    1 
ATOM   10406 C CG1   . VAL D 1 69  ? -34.049  -96.700  21.745  1.00 20.85  ? 69   VAL D CG1   1 
ATOM   10407 C CG2   . VAL D 1 69  ? -32.414  -96.410  19.868  1.00 29.73  ? 69   VAL D CG2   1 
ATOM   10408 N N     . GLY D 1 70  ? -31.540  -96.285  24.263  1.00 20.30  ? 70   GLY D N     1 
ATOM   10409 C CA    . GLY D 1 70  ? -31.479  -95.153  25.184  1.00 22.09  ? 70   GLY D CA    1 
ATOM   10410 C C     . GLY D 1 70  ? -32.831  -94.453  25.457  1.00 23.70  ? 70   GLY D C     1 
ATOM   10411 O O     . GLY D 1 70  ? -32.873  -93.366  26.050  1.00 19.93  ? 70   GLY D O     1 
ATOM   10412 N N     . ALA D 1 71  ? -33.948  -95.078  25.052  1.00 19.90  ? 71   ALA D N     1 
ATOM   10413 C CA    . ALA D 1 71  ? -35.277  -94.569  25.373  1.00 20.69  ? 71   ALA D CA    1 
ATOM   10414 C C     . ALA D 1 71  ? -35.611  -94.791  26.850  1.00 20.29  ? 71   ALA D C     1 
ATOM   10415 O O     . ALA D 1 71  ? -35.166  -95.756  27.445  1.00 21.34  ? 71   ALA D O     1 
ATOM   10416 C CB    . ALA D 1 71  ? -36.336  -95.219  24.480  1.00 19.59  ? 71   ALA D CB    1 
ATOM   10417 N N     . LYS D 1 72  ? -36.409  -93.896  27.433  1.00 21.48  ? 72   LYS D N     1 
ATOM   10418 C CA    . LYS D 1 72  ? -36.804  -94.002  28.830  1.00 21.18  ? 72   LYS D CA    1 
ATOM   10419 C C     . LYS D 1 72  ? -38.306  -94.273  28.989  1.00 21.94  ? 72   LYS D C     1 
ATOM   10420 O O     . LYS D 1 72  ? -38.809  -94.434  30.108  1.00 20.72  ? 72   LYS D O     1 
ATOM   10421 C CB    . LYS D 1 72  ? -36.368  -92.743  29.573  1.00 21.93  ? 72   LYS D CB    1 
ATOM   10422 C CG    . LYS D 1 72  ? -34.842  -92.522  29.666  1.00 24.46  ? 72   LYS D CG    1 
ATOM   10423 C CD    . LYS D 1 72  ? -34.186  -93.633  30.451  1.00 31.32  ? 72   LYS D CD    1 
ATOM   10424 C CE    . LYS D 1 72  ? -32.644  -93.612  30.524  1.00 33.36  ? 72   LYS D CE    1 
ATOM   10425 N NZ    . LYS D 1 72  ? -32.268  -92.423  31.292  1.00 46.67  ? 72   LYS D NZ    1 
ATOM   10426 N N     . TYR D 1 73  ? -39.044  -94.283  27.861  1.00 20.48  ? 73   TYR D N     1 
ATOM   10427 C CA    . TYR D 1 73  ? -40.458  -94.616  27.869  1.00 18.02  ? 73   TYR D CA    1 
ATOM   10428 C C     . TYR D 1 73  ? -40.851  -95.172  26.512  1.00 19.30  ? 73   TYR D C     1 
ATOM   10429 O O     . TYR D 1 73  ? -40.104  -95.004  25.538  1.00 23.30  ? 73   TYR D O     1 
ATOM   10430 C CB    . TYR D 1 73  ? -41.332  -93.426  28.246  1.00 18.35  ? 73   TYR D CB    1 
ATOM   10431 C CG    . TYR D 1 73  ? -41.330  -92.181  27.354  1.00 20.24  ? 73   TYR D CG    1 
ATOM   10432 C CD1   . TYR D 1 73  ? -40.172  -91.424  27.140  1.00 19.63  ? 73   TYR D CD1   1 
ATOM   10433 C CD2   . TYR D 1 73  ? -42.523  -91.721  26.789  1.00 19.00  ? 73   TYR D CD2   1 
ATOM   10434 C CE1   . TYR D 1 73  ? -40.206  -90.264  26.382  1.00 19.18  ? 73   TYR D CE1   1 
ATOM   10435 C CE2   . TYR D 1 73  ? -42.549  -90.576  26.002  1.00 20.05  ? 73   TYR D CE2   1 
ATOM   10436 C CZ    . TYR D 1 73  ? -41.393  -89.831  25.817  1.00 20.50  ? 73   TYR D CZ    1 
ATOM   10437 O OH    . TYR D 1 73  ? -41.419  -88.662  25.100  1.00 20.38  ? 73   TYR D OH    1 
ATOM   10438 N N     . ILE D 1 74  ? -42.005  -95.852  26.468  1.00 17.84  ? 74   ILE D N     1 
ATOM   10439 C CA    . ILE D 1 74  ? -42.553  -96.420  25.248  1.00 18.47  ? 74   ILE D CA    1 
ATOM   10440 C C     . ILE D 1 74  ? -44.025  -96.040  25.163  1.00 21.32  ? 74   ILE D C     1 
ATOM   10441 O O     . ILE D 1 74  ? -44.758  -96.180  26.153  1.00 21.99  ? 74   ILE D O     1 
ATOM   10442 C CB    . ILE D 1 74  ? -42.414  -97.944  25.221  1.00 19.29  ? 74   ILE D CB    1 
ATOM   10443 C CG1   . ILE D 1 74  ? -40.989  -98.418  25.560  1.00 18.04  ? 74   ILE D CG1   1 
ATOM   10444 C CG2   . ILE D 1 74  ? -42.925  -98.480  23.876  1.00 16.14  ? 74   ILE D CG2   1 
ATOM   10445 C CD1   . ILE D 1 74  ? -40.821  -99.916  25.518  1.00 14.65  ? 74   ILE D CD1   1 
ATOM   10446 N N     . VAL D 1 75  ? -44.437  -95.527  23.989  1.00 20.29  ? 75   VAL D N     1 
ATOM   10447 C CA    . VAL D 1 75  ? -45.843  -95.284  23.725  1.00 17.94  ? 75   VAL D CA    1 
ATOM   10448 C C     . VAL D 1 75  ? -46.328  -96.384  22.789  1.00 19.29  ? 75   VAL D C     1 
ATOM   10449 O O     . VAL D 1 75  ? -45.840  -96.484  21.654  1.00 21.45  ? 75   VAL D O     1 
ATOM   10450 C CB    . VAL D 1 75  ? -45.975  -93.896  23.068  1.00 18.42  ? 75   VAL D CB    1 
ATOM   10451 C CG1   . VAL D 1 75  ? -47.432  -93.563  22.760  1.00 15.04  ? 75   VAL D CG1   1 
ATOM   10452 C CG2   . VAL D 1 75  ? -45.374  -92.810  23.964  1.00 16.44  ? 75   VAL D CG2   1 
ATOM   10453 N N     . LEU D 1 76  ? -47.260  -97.215  23.264  1.00 19.55  ? 76   LEU D N     1 
ATOM   10454 C CA    . LEU D 1 76  ? -47.852  -98.296  22.465  1.00 20.03  ? 76   LEU D CA    1 
ATOM   10455 C C     . LEU D 1 76  ? -49.286  -97.935  22.045  1.00 21.49  ? 76   LEU D C     1 
ATOM   10456 O O     . LEU D 1 76  ? -50.075  -97.433  22.863  1.00 18.82  ? 76   LEU D O     1 
ATOM   10457 C CB    . LEU D 1 76  ? -47.847  -99.605  23.263  1.00 20.01  ? 76   LEU D CB    1 
ATOM   10458 C CG    . LEU D 1 76  ? -48.490  -100.828 22.592  1.00 19.10  ? 76   LEU D CG    1 
ATOM   10459 C CD1   . LEU D 1 76  ? -47.795  -101.184 21.292  1.00 15.78  ? 76   LEU D CD1   1 
ATOM   10460 C CD2   . LEU D 1 76  ? -48.457  -101.992 23.553  1.00 20.41  ? 76   LEU D CD2   1 
ATOM   10461 N N     . THR D 1 77  ? -49.609  -98.171  20.763  1.00 19.80  ? 77   THR D N     1 
ATOM   10462 C CA    . THR D 1 77  ? -50.974  -97.988  20.293  1.00 20.16  ? 77   THR D CA    1 
ATOM   10463 C C     . THR D 1 77  ? -51.896  -99.008  20.966  1.00 18.55  ? 77   THR D C     1 
ATOM   10464 O O     . THR D 1 77  ? -51.845  -100.186 20.613  1.00 21.44  ? 77   THR D O     1 
ATOM   10465 C CB    . THR D 1 77  ? -51.032  -98.123  18.760  1.00 17.49  ? 77   THR D CB    1 
ATOM   10466 O OG1   . THR D 1 77  ? -50.431  -99.366  18.383  1.00 16.31  ? 77   THR D OG1   1 
ATOM   10467 C CG2   . THR D 1 77  ? -50.350  -96.964  18.047  1.00 16.60  ? 77   THR D CG2   1 
ATOM   10468 N N     . THR D 1 78  ? -52.759  -98.571  21.901  1.00 16.76  ? 78   THR D N     1 
ATOM   10469 C CA    . THR D 1 78  ? -53.644  -99.535  22.562  1.00 17.94  ? 78   THR D CA    1 
ATOM   10470 C C     . THR D 1 78  ? -54.941  -99.690  21.760  1.00 20.77  ? 78   THR D C     1 
ATOM   10471 O O     . THR D 1 78  ? -55.618  -100.722 21.858  1.00 22.18  ? 78   THR D O     1 
ATOM   10472 C CB    . THR D 1 78  ? -53.953  -99.147  24.006  1.00 19.53  ? 78   THR D CB    1 
ATOM   10473 O OG1   . THR D 1 78  ? -54.792  -97.990  23.964  1.00 18.87  ? 78   THR D OG1   1 
ATOM   10474 C CG2   . THR D 1 78  ? -52.704  -98.923  24.842  1.00 18.57  ? 78   THR D CG2   1 
ATOM   10475 N N     . LYS D 1 79  ? -55.284  -98.636  20.986  1.00 18.20  ? 79   LYS D N     1 
ATOM   10476 C CA    . LYS D 1 79  ? -56.403  -98.648  20.051  1.00 20.51  ? 79   LYS D CA    1 
ATOM   10477 C C     . LYS D 1 79  ? -56.167  -97.514  19.062  1.00 18.82  ? 79   LYS D C     1 
ATOM   10478 O O     . LYS D 1 79  ? -56.101  -96.352  19.472  1.00 20.07  ? 79   LYS D O     1 
ATOM   10479 C CB    . LYS D 1 79  ? -57.739  -98.397  20.772  1.00 20.23  ? 79   LYS D CB    1 
ATOM   10480 C CG    . LYS D 1 79  ? -58.975  -98.607  19.894  1.00 20.61  ? 79   LYS D CG    1 
ATOM   10481 C CD    . LYS D 1 79  ? -60.202  -97.733  20.247  1.00 19.46  ? 79   LYS D CD    1 
ATOM   10482 C CE    . LYS D 1 79  ? -59.979  -96.283  19.876  1.00 17.47  ? 79   LYS D CE    1 
ATOM   10483 N NZ    . LYS D 1 79  ? -61.131  -95.429  20.158  1.00 18.98  ? 79   LYS D NZ    1 
ATOM   10484 N N     . HIS D 1 80  ? -56.046  -97.852  17.776  1.00 19.13  ? 80   HIS D N     1 
ATOM   10485 C CA    . HIS D 1 80  ? -55.847  -96.866  16.715  1.00 20.48  ? 80   HIS D CA    1 
ATOM   10486 C C     . HIS D 1 80  ? -57.207  -96.500  16.090  1.00 22.20  ? 80   HIS D C     1 
ATOM   10487 O O     . HIS D 1 80  ? -58.255  -96.920  16.576  1.00 22.84  ? 80   HIS D O     1 
ATOM   10488 C CB    . HIS D 1 80  ? -54.730  -97.346  15.775  1.00 17.80  ? 80   HIS D CB    1 
ATOM   10489 C CG    . HIS D 1 80  ? -54.025  -96.207  15.113  1.00 22.46  ? 80   HIS D CG    1 
ATOM   10490 N ND1   . HIS D 1 80  ? -54.454  -95.596  13.955  1.00 20.79  ? 80   HIS D ND1   1 
ATOM   10491 C CD2   . HIS D 1 80  ? -52.938  -95.512  15.505  1.00 23.13  ? 80   HIS D CD2   1 
ATOM   10492 C CE1   . HIS D 1 80  ? -53.638  -94.592  13.662  1.00 21.22  ? 80   HIS D CE1   1 
ATOM   10493 N NE2   . HIS D 1 80  ? -52.721  -94.529  14.585  1.00 22.47  ? 80   HIS D NE2   1 
ATOM   10494 N N     . HIS D 1 81  ? -57.213  -95.733  14.997  1.00 21.97  ? 81   HIS D N     1 
ATOM   10495 C CA    . HIS D 1 81  ? -58.478  -95.327  14.375  1.00 21.99  ? 81   HIS D CA    1 
ATOM   10496 C C     . HIS D 1 81  ? -59.335  -96.544  14.003  1.00 19.69  ? 81   HIS D C     1 
ATOM   10497 O O     . HIS D 1 81  ? -60.556  -96.488  14.084  1.00 21.92  ? 81   HIS D O     1 
ATOM   10498 C CB    . HIS D 1 81  ? -58.239  -94.436  13.145  1.00 19.08  ? 81   HIS D CB    1 
ATOM   10499 C CG    . HIS D 1 81  ? -57.411  -93.252  13.430  1.00 19.06  ? 81   HIS D CG    1 
ATOM   10500 N ND1   . HIS D 1 81  ? -57.673  -92.413  14.500  1.00 24.02  ? 81   HIS D ND1   1 
ATOM   10501 C CD2   . HIS D 1 81  ? -56.305  -92.734  12.806  1.00 19.32  ? 81   HIS D CD2   1 
ATOM   10502 C CE1   . HIS D 1 81  ? -56.766  -91.415  14.530  1.00 21.46  ? 81   HIS D CE1   1 
ATOM   10503 N NE2   . HIS D 1 81  ? -55.929  -91.594  13.502  1.00 20.72  ? 81   HIS D NE2   1 
ATOM   10504 N N     . GLU D 1 82  ? -58.707  -97.635  13.566  1.00 20.79  ? 82   GLU D N     1 
ATOM   10505 C CA    . GLU D 1 82  ? -59.461  -98.825  13.184  1.00 20.33  ? 82   GLU D CA    1 
ATOM   10506 C C     . GLU D 1 82  ? -60.336  -99.307  14.359  1.00 23.04  ? 82   GLU D C     1 
ATOM   10507 O O     . GLU D 1 82  ? -61.278  -100.081 14.146  1.00 24.19  ? 82   GLU D O     1 
ATOM   10508 C CB    . GLU D 1 82  ? -58.545  -99.962  12.731  1.00 18.25  ? 82   GLU D CB    1 
ATOM   10509 C CG    . GLU D 1 82  ? -57.528  -100.356 13.809  1.00 19.54  ? 82   GLU D CG    1 
ATOM   10510 C CD    . GLU D 1 82  ? -56.640  -101.565 13.587  1.00 21.73  ? 82   GLU D CD    1 
ATOM   10511 O OE1   . GLU D 1 82  ? -56.521  -102.044 12.422  1.00 23.13  ? 82   GLU D OE1   1 
ATOM   10512 O OE2   . GLU D 1 82  ? -56.068  -102.044 14.613  1.00 22.03  ? 82   GLU D OE2   1 
ATOM   10513 N N     . GLY D 1 83  ? -59.985  -98.939  15.613  1.00 19.75  ? 83   GLY D N     1 
ATOM   10514 C CA    . GLY D 1 83  ? -60.892  -99.137  16.733  1.00 17.40  ? 83   GLY D CA    1 
ATOM   10515 C C     . GLY D 1 83  ? -60.749  -100.509 17.417  1.00 20.96  ? 83   GLY D C     1 
ATOM   10516 O O     . GLY D 1 83  ? -61.547  -100.840 18.290  1.00 18.76  ? 83   GLY D O     1 
ATOM   10517 N N     . PHE D 1 84  ? -59.743  -101.312 17.032  1.00 21.18  ? 84   PHE D N     1 
ATOM   10518 C CA    . PHE D 1 84  ? -59.466  -102.598 17.666  1.00 21.68  ? 84   PHE D CA    1 
ATOM   10519 C C     . PHE D 1 84  ? -58.580  -102.416 18.902  1.00 22.49  ? 84   PHE D C     1 
ATOM   10520 O O     . PHE D 1 84  ? -57.564  -101.715 18.856  1.00 21.69  ? 84   PHE D O     1 
ATOM   10521 C CB    . PHE D 1 84  ? -58.769  -103.470 16.627  1.00 20.21  ? 84   PHE D CB    1 
ATOM   10522 C CG    . PHE D 1 84  ? -58.205  -104.745 17.213  1.00 22.49  ? 84   PHE D CG    1 
ATOM   10523 C CD1   . PHE D 1 84  ? -59.049  -105.801 17.571  1.00 25.71  ? 84   PHE D CD1   1 
ATOM   10524 C CD2   . PHE D 1 84  ? -56.827  -104.895 17.412  1.00 21.08  ? 84   PHE D CD2   1 
ATOM   10525 C CE1   . PHE D 1 84  ? -58.517  -106.981 18.112  1.00 23.90  ? 84   PHE D CE1   1 
ATOM   10526 C CE2   . PHE D 1 84  ? -56.298  -106.067 17.950  1.00 20.37  ? 84   PHE D CE2   1 
ATOM   10527 C CZ    . PHE D 1 84  ? -57.141  -107.104 18.312  1.00 23.28  ? 84   PHE D CZ    1 
ATOM   10528 N N     . PHE D 1 85  ? -58.957  -103.073 20.011  1.00 20.22  ? 85   PHE D N     1 
ATOM   10529 C CA    . PHE D 1 85  ? -58.264  -102.859 21.272  1.00 21.24  ? 85   PHE D CA    1 
ATOM   10530 C C     . PHE D 1 85  ? -57.267  -103.982 21.548  1.00 21.57  ? 85   PHE D C     1 
ATOM   10531 O O     . PHE D 1 85  ? -57.619  -105.158 21.475  1.00 19.86  ? 85   PHE D O     1 
ATOM   10532 C CB    . PHE D 1 85  ? -59.269  -102.846 22.427  1.00 18.93  ? 85   PHE D CB    1 
ATOM   10533 C CG    . PHE D 1 85  ? -60.351  -101.781 22.365  1.00 18.87  ? 85   PHE D CG    1 
ATOM   10534 C CD1   . PHE D 1 85  ? -61.551  -102.013 21.682  1.00 17.80  ? 85   PHE D CD1   1 
ATOM   10535 C CD2   . PHE D 1 85  ? -60.200  -100.579 23.050  1.00 18.44  ? 85   PHE D CD2   1 
ATOM   10536 C CE1   . PHE D 1 85  ? -62.545  -101.038 21.643  1.00 17.10  ? 85   PHE D CE1   1 
ATOM   10537 C CE2   . PHE D 1 85  ? -61.199  -99.616  23.027  1.00 17.41  ? 85   PHE D CE2   1 
ATOM   10538 C CZ    . PHE D 1 85  ? -62.382  -99.856  22.338  1.00 18.44  ? 85   PHE D CZ    1 
ATOM   10539 N N     . LEU D 1 86  ? -56.044  -103.597 21.932  1.00 21.29  ? 86   LEU D N     1 
ATOM   10540 C CA    . LEU D 1 86  ? -54.990  -104.564 22.210  1.00 19.95  ? 86   LEU D CA    1 
ATOM   10541 C C     . LEU D 1 86  ? -55.047  -105.059 23.664  1.00 22.88  ? 86   LEU D C     1 
ATOM   10542 O O     . LEU D 1 86  ? -54.121  -105.701 24.146  1.00 27.32  ? 86   LEU D O     1 
ATOM   10543 C CB    . LEU D 1 86  ? -53.636  -103.959 21.877  1.00 16.27  ? 86   LEU D CB    1 
ATOM   10544 C CG    . LEU D 1 86  ? -53.191  -104.084 20.408  1.00 19.04  ? 86   LEU D CG    1 
ATOM   10545 C CD1   . LEU D 1 86  ? -53.999  -103.159 19.456  1.00 17.74  ? 86   LEU D CD1   1 
ATOM   10546 C CD2   . LEU D 1 86  ? -51.702  -103.753 20.349  1.00 15.56  ? 86   LEU D CD2   1 
ATOM   10547 N N     . TYR D 1 87  ? -56.134  -104.758 24.376  1.00 22.09  ? 87   TYR D N     1 
ATOM   10548 C CA    . TYR D 1 87  ? -56.268  -105.190 25.760  1.00 23.64  ? 87   TYR D CA    1 
ATOM   10549 C C     . TYR D 1 87  ? -57.691  -105.716 26.023  1.00 25.51  ? 87   TYR D C     1 
ATOM   10550 O O     . TYR D 1 87  ? -58.584  -105.581 25.175  1.00 25.99  ? 87   TYR D O     1 
ATOM   10551 C CB    . TYR D 1 87  ? -55.943  -104.025 26.700  1.00 19.41  ? 87   TYR D CB    1 
ATOM   10552 C CG    . TYR D 1 87  ? -56.792  -102.770 26.506  1.00 20.44  ? 87   TYR D CG    1 
ATOM   10553 C CD1   . TYR D 1 87  ? -56.539  -101.879 25.460  1.00 17.79  ? 87   TYR D CD1   1 
ATOM   10554 C CD2   . TYR D 1 87  ? -57.827  -102.460 27.385  1.00 19.41  ? 87   TYR D CD2   1 
ATOM   10555 C CE1   . TYR D 1 87  ? -57.283  -100.715 25.302  1.00 18.37  ? 87   TYR D CE1   1 
ATOM   10556 C CE2   . TYR D 1 87  ? -58.550  -101.282 27.238  1.00 19.10  ? 87   TYR D CE2   1 
ATOM   10557 C CZ    . TYR D 1 87  ? -58.270  -100.394 26.211  1.00 19.53  ? 87   TYR D CZ    1 
ATOM   10558 O OH    . TYR D 1 87  ? -58.996  -99.232  26.095  1.00 15.95  ? 87   TYR D OH    1 
ATOM   10559 N N     . ASP D 1 88  ? -57.890  -106.265 27.235  1.00 23.64  ? 88   ASP D N     1 
ATOM   10560 C CA    . ASP D 1 88  ? -59.187  -106.791 27.607  1.00 23.99  ? 88   ASP D CA    1 
ATOM   10561 C C     . ASP D 1 88  ? -60.116  -105.639 28.002  1.00 25.29  ? 88   ASP D C     1 
ATOM   10562 O O     . ASP D 1 88  ? -59.938  -105.041 29.065  1.00 21.66  ? 88   ASP D O     1 
ATOM   10563 C CB    . ASP D 1 88  ? -59.033  -107.768 28.763  1.00 28.49  ? 88   ASP D CB    1 
ATOM   10564 C CG    . ASP D 1 88  ? -60.309  -108.498 29.182  1.00 29.45  ? 88   ASP D CG    1 
ATOM   10565 O OD1   . ASP D 1 88  ? -61.429  -108.087 28.771  1.00 29.95  ? 88   ASP D OD1   1 
ATOM   10566 O OD2   . ASP D 1 88  ? -60.189  -109.503 29.892  1.00 31.58  ? 88   ASP D OD2   1 
ATOM   10567 N N     . THR D 1 89  ? -61.145  -105.369 27.183  1.00 23.31  ? 89   THR D N     1 
ATOM   10568 C CA    . THR D 1 89  ? -62.019  -104.240 27.482  1.00 22.50  ? 89   THR D CA    1 
ATOM   10569 C C     . THR D 1 89  ? -63.110  -104.632 28.473  1.00 22.55  ? 89   THR D C     1 
ATOM   10570 O O     . THR D 1 89  ? -63.985  -103.798 28.740  1.00 22.52  ? 89   THR D O     1 
ATOM   10571 C CB    . THR D 1 89  ? -62.631  -103.639 26.209  1.00 20.94  ? 89   THR D CB    1 
ATOM   10572 O OG1   . THR D 1 89  ? -63.491  -104.615 25.631  1.00 21.02  ? 89   THR D OG1   1 
ATOM   10573 C CG2   . THR D 1 89  ? -61.575  -103.287 25.178  1.00 22.16  ? 89   THR D CG2   1 
ATOM   10574 N N     . LYS D 1 90  ? -63.092  -105.900 28.954  1.00 22.56  ? 90   LYS D N     1 
ATOM   10575 C CA    . LYS D 1 90  ? -63.971  -106.380 30.021  1.00 26.84  ? 90   LYS D CA    1 
ATOM   10576 C C     . LYS D 1 90  ? -65.446  -106.115 29.709  1.00 28.45  ? 90   LYS D C     1 
ATOM   10577 O O     . LYS D 1 90  ? -66.182  -105.572 30.548  1.00 27.48  ? 90   LYS D O     1 
ATOM   10578 C CB    . LYS D 1 90  ? -63.660  -105.654 31.345  1.00 28.89  ? 90   LYS D CB    1 
ATOM   10579 C CG    . LYS D 1 90  ? -62.224  -105.820 31.810  1.00 35.89  ? 90   LYS D CG    1 
ATOM   10580 C CD    . LYS D 1 90  ? -62.104  -105.155 33.170  1.00 52.38  ? 90   LYS D CD    1 
ATOM   10581 C CE    . LYS D 1 90  ? -62.034  -106.189 34.266  1.00 61.93  ? 90   LYS D CE    1 
ATOM   10582 N NZ    . LYS D 1 90  ? -62.048  -105.357 35.467  1.00 56.05  ? 90   LYS D NZ    1 
ATOM   10583 N N     . GLY D 1 91  ? -65.855  -106.439 28.475  1.00 29.10  ? 91   GLY D N     1 
ATOM   10584 C CA    . GLY D 1 91  ? -67.253  -106.320 28.108  1.00 28.00  ? 91   GLY D CA    1 
ATOM   10585 C C     . GLY D 1 91  ? -67.583  -105.038 27.357  1.00 28.19  ? 91   GLY D C     1 
ATOM   10586 O O     . GLY D 1 91  ? -68.676  -104.945 26.813  1.00 29.72  ? 91   GLY D O     1 
ATOM   10587 N N     . LEU D 1 92  ? -66.677  -104.047 27.307  1.00 26.30  ? 92   LEU D N     1 
ATOM   10588 C CA    . LEU D 1 92  ? -67.035  -102.847 26.559  1.00 25.02  ? 92   LEU D CA    1 
ATOM   10589 C C     . LEU D 1 92  ? -67.212  -103.160 25.068  1.00 25.03  ? 92   LEU D C     1 
ATOM   10590 O O     . LEU D 1 92  ? -68.084  -102.591 24.413  1.00 22.69  ? 92   LEU D O     1 
ATOM   10591 C CB    . LEU D 1 92  ? -66.023  -101.733 26.769  1.00 28.51  ? 92   LEU D CB    1 
ATOM   10592 C CG    . LEU D 1 92  ? -66.327  -100.464 25.971  1.00 29.50  ? 92   LEU D CG    1 
ATOM   10593 C CD1   . LEU D 1 92  ? -67.613  -99.743  26.492  1.00 26.56  ? 92   LEU D CD1   1 
ATOM   10594 C CD2   . LEU D 1 92  ? -65.092  -99.547  25.970  1.00 25.15  ? 92   LEU D CD2   1 
ATOM   10595 N N     . SER D 1 93  ? -66.378  -104.062 24.522  1.00 25.18  ? 93   SER D N     1 
ATOM   10596 C CA    . SER D 1 93  ? -66.390  -104.296 23.086  1.00 23.53  ? 93   SER D CA    1 
ATOM   10597 C C     . SER D 1 93  ? -65.974  -105.737 22.805  1.00 23.05  ? 93   SER D C     1 
ATOM   10598 O O     . SER D 1 93  ? -65.151  -106.281 23.518  1.00 22.41  ? 93   SER D O     1 
ATOM   10599 C CB    . SER D 1 93  ? -65.461  -103.305 22.373  1.00 22.66  ? 93   SER D CB    1 
ATOM   10600 O OG    . SER D 1 93  ? -65.242  -103.711 21.021  1.00 25.24  ? 93   SER D OG    1 
ATOM   10601 N N     . ASP D 1 94  ? -66.490  -106.321 21.725  1.00 23.88  ? 94   ASP D N     1 
ATOM   10602 C CA    . ASP D 1 94  ? -66.036  -107.638 21.286  1.00 31.10  ? 94   ASP D CA    1 
ATOM   10603 C C     . ASP D 1 94  ? -64.851  -107.529 20.325  1.00 28.21  ? 94   ASP D C     1 
ATOM   10604 O O     . ASP D 1 94  ? -64.281  -108.550 19.928  1.00 29.11  ? 94   ASP D O     1 
ATOM   10605 C CB    . ASP D 1 94  ? -67.154  -108.318 20.506  1.00 39.47  ? 94   ASP D CB    1 
ATOM   10606 C CG    . ASP D 1 94  ? -68.284  -108.880 21.363  1.00 56.48  ? 94   ASP D CG    1 
ATOM   10607 O OD1   . ASP D 1 94  ? -68.078  -109.002 22.615  1.00 53.26  ? 94   ASP D OD1   1 
ATOM   10608 O OD2   . ASP D 1 94  ? -69.363  -109.157 20.772  1.00 60.65  ? 94   ASP D OD2   1 
ATOM   10609 N N     . PHE D 1 95  ? -64.529  -106.292 19.912  1.00 21.21  ? 95   PHE D N     1 
ATOM   10610 C CA    . PHE D 1 95  ? -63.473  -106.099 18.937  1.00 23.79  ? 95   PHE D CA    1 
ATOM   10611 C C     . PHE D 1 95  ? -62.161  -105.839 19.694  1.00 24.29  ? 95   PHE D C     1 
ATOM   10612 O O     . PHE D 1 95  ? -61.619  -104.727 19.670  1.00 21.90  ? 95   PHE D O     1 
ATOM   10613 C CB    . PHE D 1 95  ? -63.924  -104.907 18.076  1.00 20.84  ? 95   PHE D CB    1 
ATOM   10614 C CG    . PHE D 1 95  ? -63.183  -104.761 16.751  1.00 19.26  ? 95   PHE D CG    1 
ATOM   10615 C CD1   . PHE D 1 95  ? -62.969  -105.883 15.920  1.00 16.89  ? 95   PHE D CD1   1 
ATOM   10616 C CD2   . PHE D 1 95  ? -62.704  -103.511 16.347  1.00 16.84  ? 95   PHE D CD2   1 
ATOM   10617 C CE1   . PHE D 1 95  ? -62.301  -105.727 14.710  1.00 17.49  ? 95   PHE D CE1   1 
ATOM   10618 C CE2   . PHE D 1 95  ? -62.061  -103.361 15.121  1.00 17.50  ? 95   PHE D CE2   1 
ATOM   10619 C CZ    . PHE D 1 95  ? -61.848  -104.471 14.307  1.00 16.26  ? 95   PHE D CZ    1 
ATOM   10620 N N     . ASP D 1 96  ? -61.699  -106.854 20.437  1.00 22.09  ? 96   ASP D N     1 
ATOM   10621 C CA    . ASP D 1 96  ? -60.527  -106.715 21.276  1.00 22.24  ? 96   ASP D CA    1 
ATOM   10622 C C     . ASP D 1 96  ? -59.732  -108.010 21.229  1.00 22.47  ? 96   ASP D C     1 
ATOM   10623 O O     . ASP D 1 96  ? -60.177  -109.016 20.682  1.00 25.27  ? 96   ASP D O     1 
ATOM   10624 C CB    . ASP D 1 96  ? -60.893  -106.206 22.661  1.00 25.43  ? 96   ASP D CB    1 
ATOM   10625 C CG    . ASP D 1 96  ? -61.455  -107.220 23.669  1.00 30.66  ? 96   ASP D CG    1 
ATOM   10626 O OD1   . ASP D 1 96  ? -61.392  -108.442 23.384  1.00 31.98  ? 96   ASP D OD1   1 
ATOM   10627 O OD2   . ASP D 1 96  ? -61.942  -106.776 24.759  1.00 28.55  ? 96   ASP D OD2   1 
ATOM   10628 N N     . VAL D 1 97  ? -58.552  -107.980 21.836  1.00 22.33  ? 97   VAL D N     1 
ATOM   10629 C CA    . VAL D 1 97  ? -57.598  -109.055 21.666  1.00 23.21  ? 97   VAL D CA    1 
ATOM   10630 C C     . VAL D 1 97  ? -58.106  -110.332 22.350  1.00 26.67  ? 97   VAL D C     1 
ATOM   10631 O O     . VAL D 1 97  ? -57.697  -111.427 21.982  1.00 26.64  ? 97   VAL D O     1 
ATOM   10632 C CB    . VAL D 1 97  ? -56.244  -108.587 22.234  1.00 21.80  ? 97   VAL D CB    1 
ATOM   10633 C CG1   . VAL D 1 97  ? -56.325  -108.350 23.743  1.00 19.43  ? 97   VAL D CG1   1 
ATOM   10634 C CG2   . VAL D 1 97  ? -55.133  -109.564 21.889  1.00 20.90  ? 97   VAL D CG2   1 
ATOM   10635 N N     . MET D 1 98  ? -59.000  -110.204 23.343  1.00 27.29  ? 98   MET D N     1 
ATOM   10636 C CA    . MET D 1 98  ? -59.551  -111.391 24.002  1.00 29.75  ? 98   MET D CA    1 
ATOM   10637 C C     . MET D 1 98  ? -60.486  -112.167 23.066  1.00 29.19  ? 98   MET D C     1 
ATOM   10638 O O     . MET D 1 98  ? -60.730  -113.329 23.300  1.00 34.03  ? 98   MET D O     1 
ATOM   10639 C CB    . MET D 1 98  ? -60.246  -111.062 25.326  1.00 24.97  ? 98   MET D CB    1 
ATOM   10640 C CG    . MET D 1 98  ? -59.321  -110.375 26.308  1.00 31.31  ? 98   MET D CG    1 
ATOM   10641 S SD    . MET D 1 98  ? -57.711  -111.128 26.649  1.00 45.86  ? 98   MET D SD    1 
ATOM   10642 C CE    . MET D 1 98  ? -58.084  -112.710 27.426  1.00 39.90  ? 98   MET D CE    1 
ATOM   10643 N N     . HIS D 1 99  ? -60.950  -111.548 21.978  1.00 26.29  ? 99   HIS D N     1 
ATOM   10644 C CA    . HIS D 1 99  ? -61.778  -112.227 20.999  1.00 26.58  ? 99   HIS D CA    1 
ATOM   10645 C C     . HIS D 1 99  ? -60.945  -112.586 19.767  1.00 29.37  ? 99   HIS D C     1 
ATOM   10646 O O     . HIS D 1 99  ? -61.497  -112.922 18.727  1.00 28.03  ? 99   HIS D O     1 
ATOM   10647 C CB    . HIS D 1 99  ? -62.984  -111.362 20.623  1.00 28.64  ? 99   HIS D CB    1 
ATOM   10648 C CG    . HIS D 1 99  ? -63.896  -111.154 21.793  1.00 35.09  ? 99   HIS D CG    1 
ATOM   10649 N ND1   . HIS D 1 99  ? -63.602  -110.299 22.839  1.00 34.76  ? 99   HIS D ND1   1 
ATOM   10650 C CD2   . HIS D 1 99  ? -65.060  -111.745 22.113  1.00 31.90  ? 99   HIS D CD2   1 
ATOM   10651 C CE1   . HIS D 1 99  ? -64.594  -110.328 23.730  1.00 32.04  ? 99   HIS D CE1   1 
ATOM   10652 N NE2   . HIS D 1 99  ? -65.492  -111.198 23.292  1.00 37.04  ? 99   HIS D NE2   1 
ATOM   10653 N N     . ALA D 1 100 ? -59.670  -112.356 19.828  1.00 27.58  ? 100  ALA D N     1 
ATOM   10654 C CA    . ALA D 1 100 ? -58.760  -112.714 18.787  1.00 25.59  ? 100  ALA D CA    1 
ATOM   10655 C C     . ALA D 1 100 ? -58.096  -114.013 19.190  1.00 25.55  ? 100  ALA D C     1 
ATOM   10656 O O     . ALA D 1 100 ? -58.128  -114.402 20.305  1.00 32.09  ? 100  ALA D O     1 
ATOM   10657 C CB    . ALA D 1 100 ? -57.739  -111.624 18.615  1.00 21.67  ? 100  ALA D CB    1 
ATOM   10658 N N     . PRO D 1 101 ? -57.455  -114.698 18.267  1.00 26.41  ? 101  PRO D N     1 
ATOM   10659 C CA    . PRO D 1 101 ? -56.761  -115.929 18.604  1.00 28.97  ? 101  PRO D CA    1 
ATOM   10660 C C     . PRO D 1 101 ? -55.619  -115.736 19.586  1.00 32.86  ? 101  PRO D C     1 
ATOM   10661 O O     . PRO D 1 101 ? -55.211  -116.651 20.236  1.00 35.91  ? 101  PRO D O     1 
ATOM   10662 C CB    . PRO D 1 101 ? -56.249  -116.436 17.270  1.00 27.30  ? 101  PRO D CB    1 
ATOM   10663 C CG    . PRO D 1 101 ? -56.587  -115.427 16.277  1.00 27.91  ? 101  PRO D CG    1 
ATOM   10664 C CD    . PRO D 1 101 ? -57.674  -114.604 16.830  1.00 28.18  ? 101  PRO D CD    1 
ATOM   10665 N N     . ALA D 1 102 ? -55.097  -114.542 19.687  1.00 31.38  ? 102  ALA D N     1 
ATOM   10666 C CA    . ALA D 1 102 ? -54.033  -114.304 20.614  1.00 28.08  ? 102  ALA D CA    1 
ATOM   10667 C C     . ALA D 1 102 ? -54.417  -114.578 22.067  1.00 29.49  ? 102  ALA D C     1 
ATOM   10668 O O     . ALA D 1 102 ? -53.651  -115.124 22.791  1.00 29.71  ? 102  ALA D O     1 
ATOM   10669 C CB    . ALA D 1 102 ? -53.554  -112.892 20.459  1.00 26.00  ? 102  ALA D CB    1 
ATOM   10670 N N     . ARG D 1 103 ? -55.583  -114.140 22.487  1.00 28.39  ? 103  ARG D N     1 
ATOM   10671 C CA    . ARG D 1 103 ? -56.112  -114.353 23.824  1.00 36.21  ? 103  ARG D CA    1 
ATOM   10672 C C     . ARG D 1 103 ? -55.202  -113.948 24.957  1.00 34.31  ? 103  ARG D C     1 
ATOM   10673 O O     . ARG D 1 103 ? -55.151  -114.619 25.929  1.00 34.26  ? 103  ARG D O     1 
ATOM   10674 C CB    . ARG D 1 103 ? -56.593  -115.790 24.064  1.00 43.34  ? 103  ARG D CB    1 
ATOM   10675 C CG    . ARG D 1 103 ? -57.340  -116.481 22.964  1.00 52.71  ? 103  ARG D CG    1 
ATOM   10676 C CD    . ARG D 1 103 ? -58.833  -116.300 23.007  1.00 79.49  ? 103  ARG D CD    1 
ATOM   10677 N NE    . ARG D 1 103 ? -59.347  -116.406 21.644  1.00 107.74 ? 103  ARG D NE    1 
ATOM   10678 C CZ    . ARG D 1 103 ? -60.615  -116.282 21.262  1.00 101.77 ? 103  ARG D CZ    1 
ATOM   10679 N NH1   . ARG D 1 103 ? -60.923  -116.397 19.982  1.00 95.41  ? 103  ARG D NH1   1 
ATOM   10680 N NH2   . ARG D 1 103 ? -61.563  -116.051 22.138  1.00 85.96  ? 103  ARG D NH2   1 
ATOM   10681 N N     . ARG D 1 104 ? -54.498  -112.850 24.819  1.00 32.90  ? 104  ARG D N     1 
ATOM   10682 C CA    . ARG D 1 104 ? -53.593  -112.361 25.814  1.00 29.81  ? 104  ARG D CA    1 
ATOM   10683 C C     . ARG D 1 104 ? -53.829  -110.886 25.948  1.00 31.48  ? 104  ARG D C     1 
ATOM   10684 O O     . ARG D 1 104 ? -54.041  -110.242 24.976  1.00 27.86  ? 104  ARG D O     1 
ATOM   10685 C CB    . ARG D 1 104 ? -52.170  -112.524 25.321  1.00 30.05  ? 104  ARG D CB    1 
ATOM   10686 C CG    . ARG D 1 104 ? -51.609  -113.910 25.245  1.00 29.88  ? 104  ARG D CG    1 
ATOM   10687 C CD    . ARG D 1 104 ? -50.673  -114.039 24.080  1.00 28.95  ? 104  ARG D CD    1 
ATOM   10688 N NE    . ARG D 1 104 ? -49.511  -113.202 24.175  1.00 30.21  ? 104  ARG D NE    1 
ATOM   10689 C CZ    . ARG D 1 104 ? -48.573  -113.149 23.254  1.00 33.05  ? 104  ARG D CZ    1 
ATOM   10690 N NH1   . ARG D 1 104 ? -48.674  -113.889 22.193  1.00 24.96  ? 104  ARG D NH1   1 
ATOM   10691 N NH2   . ARG D 1 104 ? -47.543  -112.365 23.401  1.00 28.82  ? 104  ARG D NH2   1 
ATOM   10692 N N     . ASP D 1 105 ? -53.741  -110.338 27.143  1.00 27.06  ? 105  ASP D N     1 
ATOM   10693 C CA    . ASP D 1 105 ? -53.883  -108.922 27.286  1.00 25.65  ? 105  ASP D CA    1 
ATOM   10694 C C     . ASP D 1 105 ? -52.465  -108.445 27.010  1.00 29.54  ? 105  ASP D C     1 
ATOM   10695 O O     . ASP D 1 105 ? -51.583  -108.605 27.800  1.00 29.59  ? 105  ASP D O     1 
ATOM   10696 C CB    . ASP D 1 105 ? -54.376  -108.554 28.676  1.00 22.11  ? 105  ASP D CB    1 
ATOM   10697 C CG    . ASP D 1 105 ? -54.728  -107.107 28.815  1.00 27.95  ? 105  ASP D CG    1 
ATOM   10698 O OD1   . ASP D 1 105 ? -54.092  -106.282 28.220  1.00 29.04  ? 105  ASP D OD1   1 
ATOM   10699 O OD2   . ASP D 1 105 ? -55.652  -106.784 29.526  1.00 24.23  ? 105  ASP D OD2   1 
ATOM   10700 N N     . LEU D 1 106 ? -52.297  -107.833 25.851  1.00 24.29  ? 106  LEU D N     1 
ATOM   10701 C CA    . LEU D 1 106 ? -50.988  -107.397 25.375  1.00 22.05  ? 106  LEU D CA    1 
ATOM   10702 C C     . LEU D 1 106 ? -50.524  -106.177 26.165  1.00 22.32  ? 106  LEU D C     1 
ATOM   10703 O O     . LEU D 1 106 ? -49.330  -106.008 26.405  1.00 22.67  ? 106  LEU D O     1 
ATOM   10704 C CB    . LEU D 1 106 ? -51.037  -107.134 23.876  1.00 20.72  ? 106  LEU D CB    1 
ATOM   10705 C CG    . LEU D 1 106 ? -51.480  -108.357 23.063  1.00 21.98  ? 106  LEU D CG    1 
ATOM   10706 C CD1   . LEU D 1 106 ? -51.796  -107.967 21.619  1.00 20.12  ? 106  LEU D CD1   1 
ATOM   10707 C CD2   . LEU D 1 106 ? -50.405  -109.463 23.135  1.00 22.41  ? 106  LEU D CD2   1 
ATOM   10708 N N     . ILE D 1 107 ? -51.474  -105.338 26.600  1.00 20.83  ? 107  ILE D N     1 
ATOM   10709 C CA    . ILE D 1 107 ? -51.128  -104.209 27.443  1.00 20.14  ? 107  ILE D CA    1 
ATOM   10710 C C     . ILE D 1 107 ? -50.547  -104.685 28.777  1.00 22.81  ? 107  ILE D C     1 
ATOM   10711 O O     . ILE D 1 107 ? -49.607  -104.061 29.277  1.00 27.46  ? 107  ILE D O     1 
ATOM   10712 C CB    . ILE D 1 107 ? -52.320  -103.241 27.581  1.00 20.66  ? 107  ILE D CB    1 
ATOM   10713 C CG1   . ILE D 1 107 ? -52.802  -102.677 26.232  1.00 22.34  ? 107  ILE D CG1   1 
ATOM   10714 C CG2   . ILE D 1 107 ? -52.090  -102.170 28.631  1.00 23.22  ? 107  ILE D CG2   1 
ATOM   10715 C CD1   . ILE D 1 107 ? -51.766  -102.458 25.193  1.00 23.24  ? 107  ILE D CD1   1 
ATOM   10716 N N     . ALA D 1 108 ? -51.063  -105.794 29.337  1.00 21.56  ? 108  ALA D N     1 
ATOM   10717 C CA    . ALA D 1 108 ? -50.530  -106.269 30.611  1.00 22.16  ? 108  ALA D CA    1 
ATOM   10718 C C     . ALA D 1 108 ? -49.088  -106.759 30.387  1.00 21.29  ? 108  ALA D C     1 
ATOM   10719 O O     . ALA D 1 108 ? -48.212  -106.474 31.196  1.00 21.21  ? 108  ALA D O     1 
ATOM   10720 C CB    . ALA D 1 108 ? -51.398  -107.379 31.227  1.00 17.30  ? 108  ALA D CB    1 
ATOM   10721 N N     . GLU D 1 109 ? -48.837  -107.461 29.273  1.00 19.94  ? 109  GLU D N     1 
ATOM   10722 C CA    . GLU D 1 109 ? -47.483  -107.894 28.939  1.00 21.77  ? 109  GLU D CA    1 
ATOM   10723 C C     . GLU D 1 109 ? -46.548  -106.691 28.792  1.00 23.13  ? 109  GLU D C     1 
ATOM   10724 O O     . GLU D 1 109 ? -45.434  -106.689 29.305  1.00 26.32  ? 109  GLU D O     1 
ATOM   10725 C CB    . GLU D 1 109 ? -47.451  -108.760 27.688  1.00 23.75  ? 109  GLU D CB    1 
ATOM   10726 C CG    . GLU D 1 109 ? -48.263  -110.042 27.827  1.00 25.56  ? 109  GLU D CG    1 
ATOM   10727 C CD    . GLU D 1 109 ? -48.224  -110.898 26.578  1.00 32.83  ? 109  GLU D CD    1 
ATOM   10728 O OE1   . GLU D 1 109 ? -47.504  -110.529 25.621  1.00 37.71  ? 109  GLU D OE1   1 
ATOM   10729 O OE2   . GLU D 1 109 ? -48.933  -111.930 26.533  1.00 38.95  ? 109  GLU D OE2   1 
ATOM   10730 N N     . PHE D 1 110 ? -47.048  -105.632 28.154  1.00 20.69  ? 110  PHE D N     1 
ATOM   10731 C CA    . PHE D 1 110 ? -46.254  -104.459 27.863  1.00 18.36  ? 110  PHE D CA    1 
ATOM   10732 C C     . PHE D 1 110 ? -45.880  -103.721 29.143  1.00 18.45  ? 110  PHE D C     1 
ATOM   10733 O O     . PHE D 1 110 ? -44.722  -103.312 29.320  1.00 20.16  ? 110  PHE D O     1 
ATOM   10734 C CB    . PHE D 1 110 ? -47.107  -103.607 26.920  1.00 18.77  ? 110  PHE D CB    1 
ATOM   10735 C CG    . PHE D 1 110 ? -46.576  -102.193 26.736  1.00 17.41  ? 110  PHE D CG    1 
ATOM   10736 C CD1   . PHE D 1 110 ? -45.375  -101.951 26.061  1.00 17.54  ? 110  PHE D CD1   1 
ATOM   10737 C CD2   . PHE D 1 110 ? -47.313  -101.101 27.205  1.00 16.99  ? 110  PHE D CD2   1 
ATOM   10738 C CE1   . PHE D 1 110 ? -44.905  -100.648 25.896  1.00 17.91  ? 110  PHE D CE1   1 
ATOM   10739 C CE2   . PHE D 1 110 ? -46.852  -99.808  27.036  1.00 17.27  ? 110  PHE D CE2   1 
ATOM   10740 C CZ    . PHE D 1 110 ? -45.656  -99.576  26.383  1.00 16.97  ? 110  PHE D CZ    1 
ATOM   10741 N N     . VAL D 1 111 ? -46.859  -103.550 30.041  1.00 19.06  ? 111  VAL D N     1 
ATOM   10742 C CA    . VAL D 1 111 ? -46.629  -102.839 31.288  1.00 19.50  ? 111  VAL D CA    1 
ATOM   10743 C C     . VAL D 1 111 ? -45.567  -103.556 32.138  1.00 19.67  ? 111  VAL D C     1 
ATOM   10744 O O     . VAL D 1 111 ? -44.654  -102.917 32.661  1.00 24.37  ? 111  VAL D O     1 
ATOM   10745 C CB    . VAL D 1 111 ? -47.972  -102.654 32.031  1.00 17.99  ? 111  VAL D CB    1 
ATOM   10746 C CG1   . VAL D 1 111 ? -47.736  -102.332 33.514  1.00 15.47  ? 111  VAL D CG1   1 
ATOM   10747 C CG2   . VAL D 1 111 ? -48.798  -101.532 31.415  1.00 15.85  ? 111  VAL D CG2   1 
ATOM   10748 N N     . ALA D 1 112 ? -45.661  -104.874 32.222  1.00 17.14  ? 112  ALA D N     1 
ATOM   10749 C CA    . ALA D 1 112 ? -44.723  -105.671 33.012  1.00 20.04  ? 112  ALA D CA    1 
ATOM   10750 C C     . ALA D 1 112 ? -43.319  -105.556 32.404  1.00 22.81  ? 112  ALA D C     1 
ATOM   10751 O O     . ALA D 1 112 ? -42.364  -105.314 33.127  1.00 23.02  ? 112  ALA D O     1 
ATOM   10752 C CB    . ALA D 1 112 ? -45.181  -107.154 33.100  1.00 13.74  ? 112  ALA D CB    1 
ATOM   10753 N N     . ALA D 1 113 ? -43.220  -105.637 31.067  1.00 20.81  ? 113  ALA D N     1 
ATOM   10754 C CA    . ALA D 1 113 ? -41.929  -105.574 30.390  1.00 20.78  ? 113  ALA D CA    1 
ATOM   10755 C C     . ALA D 1 113 ? -41.280  -104.212 30.624  1.00 23.96  ? 113  ALA D C     1 
ATOM   10756 O O     . ALA D 1 113 ? -40.083  -104.150 30.908  1.00 24.60  ? 113  ALA D O     1 
ATOM   10757 C CB    . ALA D 1 113 ? -42.068  -105.895 28.919  1.00 18.24  ? 113  ALA D CB    1 
ATOM   10758 N N     . CYS D 1 114 ? -42.086  -103.129 30.580  1.00 25.18  ? 114  CYS D N     1 
ATOM   10759 C CA    . CYS D 1 114 ? -41.521  -101.809 30.809  1.00 23.11  ? 114  CYS D CA    1 
ATOM   10760 C C     . CYS D 1 114 ? -40.985  -101.695 32.227  1.00 22.77  ? 114  CYS D C     1 
ATOM   10761 O O     . CYS D 1 114 ? -39.894  -101.159 32.442  1.00 21.83  ? 114  CYS D O     1 
ATOM   10762 C CB    . CYS D 1 114 ? -42.519  -100.687 30.581  1.00 21.80  ? 114  CYS D CB    1 
ATOM   10763 S SG    . CYS D 1 114 ? -42.941  -100.482 28.831  1.00 24.73  ? 114  CYS D SG    1 
ATOM   10764 N N     . ARG D 1 115 ? -41.754  -102.190 33.204  1.00 27.45  ? 115  ARG D N     1 
ATOM   10765 C CA    . ARG D 1 115 ? -41.369  -102.017 34.601  1.00 27.38  ? 115  ARG D CA    1 
ATOM   10766 C C     . ARG D 1 115 ? -40.070  -102.778 34.865  1.00 26.93  ? 115  ARG D C     1 
ATOM   10767 O O     . ARG D 1 115 ? -39.236  -102.298 35.596  1.00 25.19  ? 115  ARG D O     1 
ATOM   10768 C CB    . ARG D 1 115 ? -42.430  -102.468 35.605  1.00 29.78  ? 115  ARG D CB    1 
ATOM   10769 C CG    . ARG D 1 115 ? -43.516  -101.418 35.735  1.00 35.38  ? 115  ARG D CG    1 
ATOM   10770 C CD    . ARG D 1 115 ? -44.751  -102.104 36.311  1.00 31.72  ? 115  ARG D CD    1 
ATOM   10771 N NE    . ARG D 1 115 ? -45.812  -101.130 36.529  1.00 35.76  ? 115  ARG D NE    1 
ATOM   10772 C CZ    . ARG D 1 115 ? -47.114  -101.442 36.673  1.00 31.32  ? 115  ARG D CZ    1 
ATOM   10773 N NH1   . ARG D 1 115 ? -47.438  -102.709 36.719  1.00 27.28  ? 115  ARG D NH1   1 
ATOM   10774 N NH2   . ARG D 1 115 ? -48.066  -100.507 36.810  1.00 29.34  ? 115  ARG D NH2   1 
ATOM   10775 N N     . GLU D 1 116 ? -39.907  -103.970 34.281  1.00 24.73  ? 116  GLU D N     1 
ATOM   10776 C CA    . GLU D 1 116 ? -38.699  -104.735 34.497  1.00 29.18  ? 116  GLU D CA    1 
ATOM   10777 C C     . GLU D 1 116 ? -37.468  -104.022 33.930  1.00 31.41  ? 116  GLU D C     1 
ATOM   10778 O O     . GLU D 1 116 ? -36.376  -104.305 34.403  1.00 32.11  ? 116  GLU D O     1 
ATOM   10779 C CB    . GLU D 1 116 ? -38.848  -106.118 33.866  1.00 32.11  ? 116  GLU D CB    1 
ATOM   10780 C CG    . GLU D 1 116 ? -39.481  -107.146 34.794  1.00 44.68  ? 116  GLU D CG    1 
ATOM   10781 C CD    . GLU D 1 116 ? -39.942  -108.365 34.018  1.00 63.49  ? 116  GLU D CD    1 
ATOM   10782 O OE1   . GLU D 1 116 ? -41.009  -108.836 34.477  1.00 61.43  ? 116  GLU D OE1   1 
ATOM   10783 O OE2   . GLU D 1 116 ? -39.377  -108.751 32.949  1.00 71.93  ? 116  GLU D OE2   1 
ATOM   10784 N N     . GLU D 1 117 ? -37.629  -103.090 32.966  1.00 28.06  ? 117  GLU D N     1 
ATOM   10785 C CA    . GLU D 1 117 ? -36.485  -102.399 32.381  1.00 22.47  ? 117  GLU D CA    1 
ATOM   10786 C C     . GLU D 1 117 ? -36.391  -100.975 32.912  1.00 22.86  ? 117  GLU D C     1 
ATOM   10787 O O     . GLU D 1 117 ? -35.630  -100.176 32.375  1.00 26.28  ? 117  GLU D O     1 
ATOM   10788 C CB    . GLU D 1 117 ? -36.588  -102.369 30.855  1.00 21.86  ? 117  GLU D CB    1 
ATOM   10789 C CG    . GLU D 1 117 ? -36.350  -103.708 30.171  1.00 24.17  ? 117  GLU D CG    1 
ATOM   10790 C CD    . GLU D 1 117 ? -34.853  -103.985 29.915  1.00 25.93  ? 117  GLU D CD    1 
ATOM   10791 O OE1   . GLU D 1 117 ? -33.958  -103.579 30.701  1.00 29.51  ? 117  GLU D OE1   1 
ATOM   10792 O OE2   . GLU D 1 117 ? -34.522  -104.672 28.922  1.00 24.45  ? 117  GLU D OE2   1 
ATOM   10793 N N     . ASP D 1 118 ? -37.196  -100.637 33.928  1.00 22.58  ? 118  ASP D N     1 
ATOM   10794 C CA    . ASP D 1 118 ? -37.268  -99.261  34.428  1.00 28.89  ? 118  ASP D CA    1 
ATOM   10795 C C     . ASP D 1 118 ? -37.704  -98.260  33.334  1.00 30.22  ? 118  ASP D C     1 
ATOM   10796 O O     . ASP D 1 118 ? -37.251  -97.110  33.319  1.00 27.01  ? 118  ASP D O     1 
ATOM   10797 C CB    . ASP D 1 118 ? -35.988  -98.773  35.109  1.00 38.72  ? 118  ASP D CB    1 
ATOM   10798 C CG    . ASP D 1 118 ? -35.644  -99.287  36.494  1.00 64.16  ? 118  ASP D CG    1 
ATOM   10799 O OD1   . ASP D 1 118 ? -36.357  -100.157 37.065  1.00 66.62  ? 118  ASP D OD1   1 
ATOM   10800 O OD2   . ASP D 1 118 ? -34.634  -98.792  36.988  1.00 76.17  ? 118  ASP D OD2   1 
ATOM   10801 N N     . LEU D 1 119 ? -38.617  -98.655  32.421  1.00 25.45  ? 119  LEU D N     1 
ATOM   10802 C CA    . LEU D 1 119 ? -39.160  -97.710  31.455  1.00 25.05  ? 119  LEU D CA    1 
ATOM   10803 C C     . LEU D 1 119 ? -40.574  -97.322  31.892  1.00 25.47  ? 119  LEU D C     1 
ATOM   10804 O O     . LEU D 1 119 ? -41.306  -98.154  32.438  1.00 21.66  ? 119  LEU D O     1 
ATOM   10805 C CB    . LEU D 1 119 ? -39.199  -98.429  30.110  1.00 22.97  ? 119  LEU D CB    1 
ATOM   10806 C CG    . LEU D 1 119 ? -37.861  -98.961  29.587  1.00 23.41  ? 119  LEU D CG    1 
ATOM   10807 C CD1   . LEU D 1 119 ? -38.106  -99.765  28.290  1.00 20.10  ? 119  LEU D CD1   1 
ATOM   10808 C CD2   . LEU D 1 119 ? -36.875  -97.814  29.383  1.00 19.63  ? 119  LEU D CD2   1 
ATOM   10809 N N     . LEU D 1 120 ? -41.006  -96.095  31.582  1.00 24.13  ? 120  LEU D N     1 
ATOM   10810 C CA    . LEU D 1 120 ? -42.411  -95.764  31.783  1.00 20.87  ? 120  LEU D CA    1 
ATOM   10811 C C     . LEU D 1 120 ? -43.271  -96.287  30.629  1.00 21.41  ? 120  LEU D C     1 
ATOM   10812 O O     . LEU D 1 120 ? -42.982  -96.014  29.464  1.00 22.84  ? 120  LEU D O     1 
ATOM   10813 C CB    . LEU D 1 120 ? -42.573  -94.259  31.987  1.00 20.82  ? 120  LEU D CB    1 
ATOM   10814 C CG    . LEU D 1 120 ? -41.923  -93.702  33.261  1.00 23.92  ? 120  LEU D CG    1 
ATOM   10815 C CD1   . LEU D 1 120 ? -42.271  -92.238  33.371  1.00 25.54  ? 120  LEU D CD1   1 
ATOM   10816 C CD2   . LEU D 1 120 ? -42.403  -94.453  34.508  1.00 23.09  ? 120  LEU D CD2   1 
ATOM   10817 N N     . PRO D 1 121 ? -44.366  -97.045  30.898  1.00 20.27  ? 121  PRO D N     1 
ATOM   10818 C CA    . PRO D 1 121 ? -45.332  -97.413  29.850  1.00 17.61  ? 121  PRO D CA    1 
ATOM   10819 C C     . PRO D 1 121 ? -46.359  -96.321  29.584  1.00 19.50  ? 121  PRO D C     1 
ATOM   10820 O O     . PRO D 1 121 ? -46.952  -95.782  30.517  1.00 18.95  ? 121  PRO D O     1 
ATOM   10821 C CB    . PRO D 1 121 ? -46.015  -98.671  30.389  1.00 16.62  ? 121  PRO D CB    1 
ATOM   10822 C CG    . PRO D 1 121 ? -45.989  -98.363  31.901  1.00 17.79  ? 121  PRO D CG    1 
ATOM   10823 C CD    . PRO D 1 121 ? -44.722  -97.588  32.221  1.00 15.22  ? 121  PRO D CD    1 
ATOM   10824 N N     . PHE D 1 122 ? -46.514  -95.942  28.309  1.00 20.76  ? 122  PHE D N     1 
ATOM   10825 C CA    . PHE D 1 122 ? -47.505  -94.957  27.925  1.00 18.84  ? 122  PHE D CA    1 
ATOM   10826 C C     . PHE D 1 122 ? -48.510  -95.610  26.985  1.00 19.12  ? 122  PHE D C     1 
ATOM   10827 O O     . PHE D 1 122 ? -48.130  -96.448  26.154  1.00 17.28  ? 122  PHE D O     1 
ATOM   10828 C CB    . PHE D 1 122 ? -46.897  -93.765  27.181  1.00 18.34  ? 122  PHE D CB    1 
ATOM   10829 C CG    . PHE D 1 122 ? -46.273  -92.671  28.031  1.00 21.01  ? 122  PHE D CG    1 
ATOM   10830 C CD1   . PHE D 1 122 ? -45.322  -92.954  29.015  1.00 21.51  ? 122  PHE D CD1   1 
ATOM   10831 C CD2   . PHE D 1 122 ? -46.673  -91.346  27.853  1.00 21.44  ? 122  PHE D CD2   1 
ATOM   10832 C CE1   . PHE D 1 122 ? -44.772  -91.933  29.776  1.00 19.21  ? 122  PHE D CE1   1 
ATOM   10833 C CE2   . PHE D 1 122 ? -46.119  -90.330  28.623  1.00 24.72  ? 122  PHE D CE2   1 
ATOM   10834 C CZ    . PHE D 1 122 ? -45.162  -90.634  29.595  1.00 23.09  ? 122  PHE D CZ    1 
ATOM   10835 N N     . PHE D 1 123 ? -49.772  -95.164  27.073  1.00 17.72  ? 123  PHE D N     1 
ATOM   10836 C CA    . PHE D 1 123 ? -50.825  -95.735  26.245  1.00 18.83  ? 123  PHE D CA    1 
ATOM   10837 C C     . PHE D 1 123 ? -51.307  -94.724  25.224  1.00 20.09  ? 123  PHE D C     1 
ATOM   10838 O O     . PHE D 1 123 ? -51.849  -93.688  25.591  1.00 24.34  ? 123  PHE D O     1 
ATOM   10839 C CB    . PHE D 1 123 ? -52.011  -96.103  27.137  1.00 18.42  ? 123  PHE D CB    1 
ATOM   10840 C CG    . PHE D 1 123 ? -51.719  -97.163  28.193  1.00 19.34  ? 123  PHE D CG    1 
ATOM   10841 C CD1   . PHE D 1 123 ? -50.770  -98.166  27.955  1.00 17.47  ? 123  PHE D CD1   1 
ATOM   10842 C CD2   . PHE D 1 123 ? -52.417  -97.158  29.414  1.00 17.28  ? 123  PHE D CD2   1 
ATOM   10843 C CE1   . PHE D 1 123 ? -50.489  -99.128  28.924  1.00 18.55  ? 123  PHE D CE1   1 
ATOM   10844 C CE2   . PHE D 1 123 ? -52.172  -98.143  30.353  1.00 18.90  ? 123  PHE D CE2   1 
ATOM   10845 C CZ    . PHE D 1 123 ? -51.196  -99.113  30.123  1.00 19.22  ? 123  PHE D CZ    1 
ATOM   10846 N N     . TYR D 1 124 ? -51.101  -95.021  23.947  1.00 20.93  ? 124  TYR D N     1 
ATOM   10847 C CA    . TYR D 1 124 ? -51.709  -94.206  22.897  1.00 18.37  ? 124  TYR D CA    1 
ATOM   10848 C C     . TYR D 1 124 ? -53.166  -94.652  22.767  1.00 18.48  ? 124  TYR D C     1 
ATOM   10849 O O     . TYR D 1 124 ? -53.469  -95.858  22.760  1.00 16.68  ? 124  TYR D O     1 
ATOM   10850 C CB    . TYR D 1 124 ? -50.934  -94.436  21.592  1.00 17.85  ? 124  TYR D CB    1 
ATOM   10851 C CG    . TYR D 1 124 ? -51.631  -93.953  20.325  1.00 21.49  ? 124  TYR D CG    1 
ATOM   10852 C CD1   . TYR D 1 124 ? -52.747  -94.624  19.820  1.00 21.11  ? 124  TYR D CD1   1 
ATOM   10853 C CD2   . TYR D 1 124 ? -51.191  -92.828  19.632  1.00 20.27  ? 124  TYR D CD2   1 
ATOM   10854 C CE1   . TYR D 1 124 ? -53.400  -94.191  18.682  1.00 22.76  ? 124  TYR D CE1   1 
ATOM   10855 C CE2   . TYR D 1 124 ? -51.809  -92.394  18.467  1.00 22.20  ? 124  TYR D CE2   1 
ATOM   10856 C CZ    . TYR D 1 124 ? -52.948  -93.059  18.021  1.00 25.74  ? 124  TYR D CZ    1 
ATOM   10857 O OH    . TYR D 1 124 ? -53.625  -92.644  16.908  1.00 27.62  ? 124  TYR D OH    1 
ATOM   10858 N N     . MET D 1 125 ? -54.060  -93.674  22.599  1.00 18.89  ? 125  MET D N     1 
ATOM   10859 C CA    . MET D 1 125 ? -55.477  -93.967  22.393  1.00 19.27  ? 125  MET D CA    1 
ATOM   10860 C C     . MET D 1 125 ? -56.011  -93.038  21.309  1.00 19.05  ? 125  MET D C     1 
ATOM   10861 O O     . MET D 1 125 ? -55.901  -91.818  21.435  1.00 18.77  ? 125  MET D O     1 
ATOM   10862 C CB    . MET D 1 125 ? -56.259  -93.777  23.710  1.00 19.15  ? 125  MET D CB    1 
ATOM   10863 C CG    . MET D 1 125 ? -57.768  -93.747  23.531  1.00 20.60  ? 125  MET D CG    1 
ATOM   10864 S SD    . MET D 1 125 ? -58.512  -95.301  22.974  1.00 26.07  ? 125  MET D SD    1 
ATOM   10865 C CE    . MET D 1 125 ? -58.161  -96.361  24.387  1.00 20.40  ? 125  MET D CE    1 
ATOM   10866 N N     . ALA D 1 126 ? -56.567  -93.613  20.233  1.00 18.54  ? 126  ALA D N     1 
ATOM   10867 C CA    . ALA D 1 126 ? -57.179  -92.790  19.186  1.00 19.50  ? 126  ALA D CA    1 
ATOM   10868 C C     . ALA D 1 126 ? -58.573  -92.342  19.628  1.00 22.21  ? 126  ALA D C     1 
ATOM   10869 O O     . ALA D 1 126 ? -59.391  -93.157  20.053  1.00 21.88  ? 126  ALA D O     1 
ATOM   10870 C CB    . ALA D 1 126 ? -57.250  -93.561  17.886  1.00 16.96  ? 126  ALA D CB    1 
ATOM   10871 N N     . THR D 1 127 ? -58.858  -91.043  19.508  1.00 21.90  ? 127  THR D N     1 
ATOM   10872 C CA    . THR D 1 127 ? -60.174  -90.571  19.891  1.00 21.03  ? 127  THR D CA    1 
ATOM   10873 C C     . THR D 1 127 ? -61.076  -90.508  18.663  1.00 24.00  ? 127  THR D C     1 
ATOM   10874 O O     . THR D 1 127 ? -62.289  -90.445  18.812  1.00 27.40  ? 127  THR D O     1 
ATOM   10875 C CB    . THR D 1 127 ? -60.057  -89.230  20.611  1.00 23.46  ? 127  THR D CB    1 
ATOM   10876 O OG1   . THR D 1 127 ? -59.589  -88.310  19.627  1.00 23.18  ? 127  THR D OG1   1 
ATOM   10877 C CG2   . THR D 1 127 ? -59.128  -89.288  21.810  1.00 21.39  ? 127  THR D CG2   1 
ATOM   10878 N N     . TYR D 1 128 ? -60.491  -90.511  17.459  1.00 21.13  ? 128  TYR D N     1 
ATOM   10879 C CA    . TYR D 1 128 ? -61.257  -90.639  16.235  1.00 25.47  ? 128  TYR D CA    1 
ATOM   10880 C C     . TYR D 1 128 ? -61.339  -92.118  15.891  1.00 25.22  ? 128  TYR D C     1 
ATOM   10881 O O     . TYR D 1 128 ? -60.313  -92.740  15.659  1.00 27.79  ? 128  TYR D O     1 
ATOM   10882 C CB    . TYR D 1 128 ? -60.492  -89.825  15.188  1.00 27.55  ? 128  TYR D CB    1 
ATOM   10883 C CG    . TYR D 1 128 ? -60.952  -89.899  13.739  1.00 27.05  ? 128  TYR D CG    1 
ATOM   10884 C CD1   . TYR D 1 128 ? -62.282  -90.098  13.402  1.00 28.61  ? 128  TYR D CD1   1 
ATOM   10885 C CD2   . TYR D 1 128 ? -60.055  -89.732  12.690  1.00 29.08  ? 128  TYR D CD2   1 
ATOM   10886 C CE1   . TYR D 1 128 ? -62.709  -90.117  12.079  1.00 27.15  ? 128  TYR D CE1   1 
ATOM   10887 C CE2   . TYR D 1 128 ? -60.476  -89.735  11.363  1.00 27.02  ? 128  TYR D CE2   1 
ATOM   10888 C CZ    . TYR D 1 128 ? -61.804  -89.936  11.058  1.00 29.09  ? 128  TYR D CZ    1 
ATOM   10889 O OH    . TYR D 1 128 ? -62.231  -89.977  9.765   1.00 32.10  ? 128  TYR D OH    1 
ATOM   10890 N N     . ASP D 1 129 ? -62.545  -92.682  15.854  1.00 24.77  ? 129  ASP D N     1 
ATOM   10891 C CA    . ASP D 1 129 ? -62.735  -94.132  15.867  1.00 24.48  ? 129  ASP D CA    1 
ATOM   10892 C C     . ASP D 1 129 ? -63.590  -94.533  14.668  1.00 25.95  ? 129  ASP D C     1 
ATOM   10893 O O     . ASP D 1 129 ? -64.634  -93.959  14.480  1.00 31.23  ? 129  ASP D O     1 
ATOM   10894 C CB    . ASP D 1 129 ? -63.349  -94.562  17.192  1.00 20.86  ? 129  ASP D CB    1 
ATOM   10895 C CG    . ASP D 1 129 ? -63.503  -96.062  17.416  1.00 24.01  ? 129  ASP D CG    1 
ATOM   10896 O OD1   . ASP D 1 129 ? -64.074  -96.742  16.518  1.00 19.89  ? 129  ASP D OD1   1 
ATOM   10897 O OD2   . ASP D 1 129 ? -63.086  -96.541  18.512  1.00 23.79  ? 129  ASP D OD2   1 
ATOM   10898 N N     . TRP D 1 130 ? -63.143  -95.502  13.848  1.00 23.57  ? 130  TRP D N     1 
ATOM   10899 C CA    . TRP D 1 130 ? -63.855  -95.902  12.645  1.00 22.74  ? 130  TRP D CA    1 
ATOM   10900 C C     . TRP D 1 130 ? -64.727  -97.124  12.915  1.00 24.69  ? 130  TRP D C     1 
ATOM   10901 O O     . TRP D 1 130 ? -65.424  -97.590  12.012  1.00 26.73  ? 130  TRP D O     1 
ATOM   10902 C CB    . TRP D 1 130 ? -62.885  -96.238  11.493  1.00 22.53  ? 130  TRP D CB    1 
ATOM   10903 C CG    . TRP D 1 130 ? -61.949  -95.114  11.111  1.00 25.23  ? 130  TRP D CG    1 
ATOM   10904 C CD1   . TRP D 1 130 ? -62.154  -93.764  11.276  1.00 24.05  ? 130  TRP D CD1   1 
ATOM   10905 C CD2   . TRP D 1 130 ? -60.622  -95.248  10.542  1.00 21.18  ? 130  TRP D CD2   1 
ATOM   10906 N NE1   . TRP D 1 130 ? -61.063  -93.055  10.852  1.00 25.88  ? 130  TRP D NE1   1 
ATOM   10907 C CE2   . TRP D 1 130 ? -60.110  -93.938  10.393  1.00 23.77  ? 130  TRP D CE2   1 
ATOM   10908 C CE3   . TRP D 1 130 ? -59.830  -96.336  10.167  1.00 19.63  ? 130  TRP D CE3   1 
ATOM   10909 C CZ2   . TRP D 1 130 ? -58.846  -93.692  9.858   1.00 21.50  ? 130  TRP D CZ2   1 
ATOM   10910 C CZ3   . TRP D 1 130 ? -58.570  -96.099  9.661   1.00 20.69  ? 130  TRP D CZ3   1 
ATOM   10911 C CH2   . TRP D 1 130 ? -58.095  -94.793  9.499   1.00 21.05  ? 130  TRP D CH2   1 
ATOM   10912 N N     . HIS D 1 131 ? -64.582  -97.748  14.093  1.00 23.48  ? 131  HIS D N     1 
ATOM   10913 C CA    . HIS D 1 131 ? -65.232  -99.032  14.323  1.00 23.51  ? 131  HIS D CA    1 
ATOM   10914 C C     . HIS D 1 131 ? -66.665  -98.853  14.843  1.00 24.34  ? 131  HIS D C     1 
ATOM   10915 O O     . HIS D 1 131 ? -67.587  -99.442  14.290  1.00 24.00  ? 131  HIS D O     1 
ATOM   10916 C CB    . HIS D 1 131 ? -64.474  -99.875  15.342  1.00 24.27  ? 131  HIS D CB    1 
ATOM   10917 C CG    . HIS D 1 131 ? -65.229  -101.098 15.757  1.00 23.92  ? 131  HIS D CG    1 
ATOM   10918 N ND1   . HIS D 1 131 ? -65.509  -102.127 14.866  1.00 26.56  ? 131  HIS D ND1   1 
ATOM   10919 C CD2   . HIS D 1 131 ? -65.731  -101.482 16.948  1.00 20.51  ? 131  HIS D CD2   1 
ATOM   10920 C CE1   . HIS D 1 131 ? -66.165  -103.109 15.488  1.00 20.22  ? 131  HIS D CE1   1 
ATOM   10921 N NE2   . HIS D 1 131 ? -66.293  -102.740 16.771  1.00 22.79  ? 131  HIS D NE2   1 
ATOM   10922 N N     . THR D 1 132 ? -66.846  -98.080  15.924  1.00 21.13  ? 132  THR D N     1 
ATOM   10923 C CA    . THR D 1 132 ? -68.136  -97.981  16.566  1.00 22.41  ? 132  THR D CA    1 
ATOM   10924 C C     . THR D 1 132 ? -69.024  -96.992  15.799  1.00 24.45  ? 132  THR D C     1 
ATOM   10925 O O     . THR D 1 132 ? -68.642  -95.850  15.559  1.00 24.70  ? 132  THR D O     1 
ATOM   10926 C CB    . THR D 1 132 ? -67.966  -97.565  18.029  1.00 22.20  ? 132  THR D CB    1 
ATOM   10927 O OG1   . THR D 1 132 ? -69.301  -97.248  18.440  1.00 24.10  ? 132  THR D OG1   1 
ATOM   10928 C CG2   . THR D 1 132 ? -67.136  -96.306  18.222  1.00 19.32  ? 132  THR D CG2   1 
ATOM   10929 N N     . PRO D 1 133 ? -70.268  -97.385  15.439  1.00 26.93  ? 133  PRO D N     1 
ATOM   10930 C CA    . PRO D 1 133 ? -71.227  -96.446  14.847  1.00 24.91  ? 133  PRO D CA    1 
ATOM   10931 C C     . PRO D 1 133 ? -71.563  -95.264  15.754  1.00 25.84  ? 133  PRO D C     1 
ATOM   10932 O O     . PRO D 1 133 ? -71.990  -94.211  15.264  1.00 22.11  ? 133  PRO D O     1 
ATOM   10933 C CB    . PRO D 1 133 ? -72.426  -97.306  14.472  1.00 27.55  ? 133  PRO D CB    1 
ATOM   10934 C CG    . PRO D 1 133 ? -72.253  -98.602  15.286  1.00 29.80  ? 133  PRO D CG    1 
ATOM   10935 C CD    . PRO D 1 133 ? -70.801  -98.753  15.619  1.00 27.37  ? 133  PRO D CD    1 
ATOM   10936 N N     . LEU D 1 134 ? -71.268  -95.390  17.063  1.00 24.11  ? 134  LEU D N     1 
ATOM   10937 C CA    . LEU D 1 134 ? -71.500  -94.278  17.973  1.00 24.17  ? 134  LEU D CA    1 
ATOM   10938 C C     . LEU D 1 134 ? -70.774  -93.028  17.475  1.00 26.54  ? 134  LEU D C     1 
ATOM   10939 O O     . LEU D 1 134 ? -71.272  -91.922  17.654  1.00 29.08  ? 134  LEU D O     1 
ATOM   10940 C CB    . LEU D 1 134 ? -71.133  -94.582  19.427  1.00 23.41  ? 134  LEU D CB    1 
ATOM   10941 C CG    . LEU D 1 134 ? -71.819  -95.795  20.067  1.00 27.67  ? 134  LEU D CG    1 
ATOM   10942 C CD1   . LEU D 1 134 ? -71.260  -96.063  21.464  1.00 24.14  ? 134  LEU D CD1   1 
ATOM   10943 C CD2   . LEU D 1 134 ? -73.344  -95.688  20.096  1.00 23.40  ? 134  LEU D CD2   1 
ATOM   10944 N N     . TYR D 1 135 ? -69.591  -93.180  16.865  1.00 26.25  ? 135  TYR D N     1 
ATOM   10945 C CA    . TYR D 1 135 ? -68.765  -92.017  16.561  1.00 25.44  ? 135  TYR D CA    1 
ATOM   10946 C C     . TYR D 1 135 ? -69.535  -91.011  15.689  1.00 26.24  ? 135  TYR D C     1 
ATOM   10947 O O     . TYR D 1 135 ? -69.525  -89.815  15.979  1.00 23.94  ? 135  TYR D O     1 
ATOM   10948 C CB    . TYR D 1 135 ? -67.409  -92.430  15.971  1.00 22.03  ? 135  TYR D CB    1 
ATOM   10949 C CG    . TYR D 1 135 ? -66.483  -91.231  15.783  1.00 21.76  ? 135  TYR D CG    1 
ATOM   10950 C CD1   . TYR D 1 135 ? -65.714  -90.753  16.854  1.00 21.28  ? 135  TYR D CD1   1 
ATOM   10951 C CD2   . TYR D 1 135 ? -66.415  -90.540  14.567  1.00 18.19  ? 135  TYR D CD2   1 
ATOM   10952 C CE1   . TYR D 1 135 ? -64.892  -89.651  16.707  1.00 21.25  ? 135  TYR D CE1   1 
ATOM   10953 C CE2   . TYR D 1 135 ? -65.625  -89.415  14.423  1.00 18.54  ? 135  TYR D CE2   1 
ATOM   10954 C CZ    . TYR D 1 135 ? -64.839  -88.992  15.483  1.00 23.30  ? 135  TYR D CZ    1 
ATOM   10955 O OH    . TYR D 1 135 ? -64.012  -87.899  15.379  1.00 25.00  ? 135  TYR D OH    1 
ATOM   10956 N N     . ASP D 1 136 ? -70.183  -91.491  14.614  1.00 28.10  ? 136  ASP D N     1 
ATOM   10957 C CA    . ASP D 1 136 ? -70.919  -90.570  13.747  1.00 32.72  ? 136  ASP D CA    1 
ATOM   10958 C C     . ASP D 1 136 ? -72.387  -90.434  14.136  1.00 29.49  ? 136  ASP D C     1 
ATOM   10959 O O     . ASP D 1 136 ? -72.955  -89.376  13.925  1.00 29.09  ? 136  ASP D O     1 
ATOM   10960 C CB    . ASP D 1 136 ? -70.862  -90.936  12.273  1.00 35.66  ? 136  ASP D CB    1 
ATOM   10961 C CG    . ASP D 1 136 ? -69.480  -90.836  11.643  1.00 41.40  ? 136  ASP D CG    1 
ATOM   10962 O OD1   . ASP D 1 136 ? -68.789  -89.802  11.916  1.00 39.78  ? 136  ASP D OD1   1 
ATOM   10963 O OD2   . ASP D 1 136 ? -69.129  -91.783  10.886  1.00 39.88  ? 136  ASP D OD2   1 
ATOM   10964 N N     . ASP D 1 137 ? -72.970  -91.486  14.724  1.00 27.79  ? 137  ASP D N     1 
ATOM   10965 C CA    . ASP D 1 137 ? -74.407  -91.567  14.874  1.00 29.77  ? 137  ASP D CA    1 
ATOM   10966 C C     . ASP D 1 137 ? -74.883  -91.145  16.246  1.00 30.00  ? 137  ASP D C     1 
ATOM   10967 O O     . ASP D 1 137 ? -76.075  -90.925  16.377  1.00 31.44  ? 137  ASP D O     1 
ATOM   10968 C CB    . ASP D 1 137 ? -74.874  -92.886  14.311  1.00 31.44  ? 137  ASP D CB    1 
ATOM   10969 C CG    . ASP D 1 137 ? -74.590  -92.955  12.812  1.00 33.95  ? 137  ASP D CG    1 
ATOM   10970 O OD1   . ASP D 1 137 ? -74.646  -91.873  12.123  1.00 31.16  ? 137  ASP D OD1   1 
ATOM   10971 O OD2   . ASP D 1 137 ? -74.387  -94.082  12.309  1.00 29.87  ? 137  ASP D OD2   1 
ATOM   10972 N N     . ASP D 1 138 ? -73.990  -91.002  17.236  1.00 30.82  ? 138  ASP D N     1 
ATOM   10973 C CA    . ASP D 1 138 ? -74.380  -90.628  18.588  1.00 29.44  ? 138  ASP D CA    1 
ATOM   10974 C C     . ASP D 1 138 ? -73.145  -90.175  19.377  1.00 29.12  ? 138  ASP D C     1 
ATOM   10975 O O     . ASP D 1 138 ? -72.669  -90.861  20.301  1.00 28.71  ? 138  ASP D O     1 
ATOM   10976 C CB    . ASP D 1 138 ? -75.164  -91.753  19.266  1.00 26.90  ? 138  ASP D CB    1 
ATOM   10977 C CG    . ASP D 1 138 ? -75.845  -91.383  20.580  1.00 28.69  ? 138  ASP D CG    1 
ATOM   10978 O OD1   . ASP D 1 138 ? -75.714  -90.216  21.042  1.00 38.80  ? 138  ASP D OD1   1 
ATOM   10979 O OD2   . ASP D 1 138 ? -76.463  -92.282  21.186  1.00 32.25  ? 138  ASP D OD2   1 
ATOM   10980 N N     . PHE D 1 139 ? -72.658  -88.991  19.025  1.00 29.51  ? 139  PHE D N     1 
ATOM   10981 C CA    . PHE D 1 139 ? -71.373  -88.519  19.504  1.00 31.06  ? 139  PHE D CA    1 
ATOM   10982 C C     . PHE D 1 139 ? -71.336  -88.516  21.042  1.00 32.02  ? 139  PHE D C     1 
ATOM   10983 O O     . PHE D 1 139 ? -70.352  -88.982  21.644  1.00 32.11  ? 139  PHE D O     1 
ATOM   10984 C CB    . PHE D 1 139 ? -70.948  -87.213  18.815  1.00 26.01  ? 139  PHE D CB    1 
ATOM   10985 C CG    . PHE D 1 139 ? -69.512  -86.836  19.166  1.00 23.89  ? 139  PHE D CG    1 
ATOM   10986 C CD1   . PHE D 1 139 ? -68.427  -87.589  18.677  1.00 22.56  ? 139  PHE D CD1   1 
ATOM   10987 C CD2   . PHE D 1 139 ? -69.252  -85.756  20.004  1.00 24.38  ? 139  PHE D CD2   1 
ATOM   10988 C CE1   . PHE D 1 139 ? -67.135  -87.256  19.019  1.00 22.54  ? 139  PHE D CE1   1 
ATOM   10989 C CE2   . PHE D 1 139 ? -67.949  -85.428  20.376  1.00 25.10  ? 139  PHE D CE2   1 
ATOM   10990 C CZ    . PHE D 1 139 ? -66.891  -86.175  19.865  1.00 25.59  ? 139  PHE D CZ    1 
ATOM   10991 N N     . PRO D 1 140 ? -72.376  -87.995  21.736  1.00 31.74  ? 140  PRO D N     1 
ATOM   10992 C CA    . PRO D 1 140 ? -72.335  -87.985  23.204  1.00 29.75  ? 140  PRO D CA    1 
ATOM   10993 C C     . PRO D 1 140 ? -72.130  -89.381  23.792  1.00 29.18  ? 140  PRO D C     1 
ATOM   10994 O O     . PRO D 1 140 ? -71.396  -89.543  24.772  1.00 29.90  ? 140  PRO D O     1 
ATOM   10995 C CB    . PRO D 1 140 ? -73.641  -87.258  23.614  1.00 29.01  ? 140  PRO D CB    1 
ATOM   10996 C CG    . PRO D 1 140 ? -73.995  -86.439  22.365  1.00 25.30  ? 140  PRO D CG    1 
ATOM   10997 C CD    . PRO D 1 140 ? -73.574  -87.333  21.175  1.00 25.19  ? 140  PRO D CD    1 
ATOM   10998 N N     . ALA D 1 141 ? -72.764  -90.399  23.175  1.00 24.83  ? 141  ALA D N     1 
ATOM   10999 C CA    . ALA D 1 141 ? -72.607  -91.757  23.658  1.00 22.84  ? 141  ALA D CA    1 
ATOM   11000 C C     . ALA D 1 141 ? -71.218  -92.299  23.297  1.00 23.19  ? 141  ALA D C     1 
ATOM   11001 O O     . ALA D 1 141 ? -70.674  -93.155  24.000  1.00 23.60  ? 141  ALA D O     1 
ATOM   11002 C CB    . ALA D 1 141 ? -73.729  -92.624  23.091  1.00 20.67  ? 141  ALA D CB    1 
ATOM   11003 N N     . TYR D 1 142 ? -70.643  -91.809  22.180  1.00 23.32  ? 142  TYR D N     1 
ATOM   11004 C CA    . TYR D 1 142 ? -69.270  -92.129  21.806  1.00 20.90  ? 142  TYR D CA    1 
ATOM   11005 C C     . TYR D 1 142 ? -68.320  -91.652  22.918  1.00 21.04  ? 142  TYR D C     1 
ATOM   11006 O O     . TYR D 1 142 ? -67.443  -92.404  23.343  1.00 19.79  ? 142  TYR D O     1 
ATOM   11007 C CB    . TYR D 1 142 ? -68.842  -91.670  20.406  1.00 20.87  ? 142  TYR D CB    1 
ATOM   11008 C CG    . TYR D 1 142 ? -67.343  -91.891  20.250  1.00 22.97  ? 142  TYR D CG    1 
ATOM   11009 C CD1   . TYR D 1 142 ? -66.830  -93.160  20.011  1.00 23.44  ? 142  TYR D CD1   1 
ATOM   11010 C CD2   . TYR D 1 142 ? -66.437  -90.843  20.408  1.00 21.00  ? 142  TYR D CD2   1 
ATOM   11011 C CE1   . TYR D 1 142 ? -65.463  -93.394  19.919  1.00 23.33  ? 142  TYR D CE1   1 
ATOM   11012 C CE2   . TYR D 1 142 ? -65.075  -91.055  20.311  1.00 21.37  ? 142  TYR D CE2   1 
ATOM   11013 C CZ    . TYR D 1 142 ? -64.591  -92.333  20.077  1.00 23.65  ? 142  TYR D CZ    1 
ATOM   11014 O OH    . TYR D 1 142 ? -63.255  -92.567  19.993  1.00 21.65  ? 142  TYR D OH    1 
ATOM   11015 N N     . LEU D 1 143 ? -68.515  -90.417  23.407  1.00 19.26  ? 143  LEU D N     1 
ATOM   11016 C CA    . LEU D 1 143 ? -67.693  -89.902  24.483  1.00 21.11  ? 143  LEU D CA    1 
ATOM   11017 C C     . LEU D 1 143 ? -67.710  -90.825  25.696  1.00 23.69  ? 143  LEU D C     1 
ATOM   11018 O O     . LEU D 1 143 ? -66.672  -91.009  26.330  1.00 25.33  ? 143  LEU D O     1 
ATOM   11019 C CB    . LEU D 1 143 ? -68.042  -88.470  24.857  1.00 19.84  ? 143  LEU D CB    1 
ATOM   11020 C CG    . LEU D 1 143 ? -67.901  -87.473  23.710  1.00 22.22  ? 143  LEU D CG    1 
ATOM   11021 C CD1   . LEU D 1 143 ? -68.270  -86.115  24.261  1.00 18.66  ? 143  LEU D CD1   1 
ATOM   11022 C CD2   . LEU D 1 143 ? -66.476  -87.470  23.170  1.00 20.65  ? 143  LEU D CD2   1 
ATOM   11023 N N     . THR D 1 144 ? -68.864  -91.448  25.982  1.00 22.62  ? 144  THR D N     1 
ATOM   11024 C CA    . THR D 1 144 ? -68.971  -92.340  27.127  1.00 22.08  ? 144  THR D CA    1 
ATOM   11025 C C     . THR D 1 144 ? -68.136  -93.596  26.870  1.00 23.51  ? 144  THR D C     1 
ATOM   11026 O O     . THR D 1 144 ? -67.495  -94.118  27.780  1.00 26.89  ? 144  THR D O     1 
ATOM   11027 C CB    . THR D 1 144 ? -70.447  -92.669  27.404  1.00 22.88  ? 144  THR D CB    1 
ATOM   11028 O OG1   . THR D 1 144 ? -70.998  -91.407  27.758  1.00 23.86  ? 144  THR D OG1   1 
ATOM   11029 C CG2   . THR D 1 144 ? -70.685  -93.640  28.549  1.00 18.20  ? 144  THR D CG2   1 
ATOM   11030 N N     . TYR D 1 145 ? -68.191  -94.098  25.632  1.00 20.92  ? 145  TYR D N     1 
ATOM   11031 C CA    . TYR D 1 145 ? -67.453  -95.287  25.231  1.00 20.79  ? 145  TYR D CA    1 
ATOM   11032 C C     . TYR D 1 145 ? -65.950  -95.012  25.283  1.00 21.08  ? 145  TYR D C     1 
ATOM   11033 O O     . TYR D 1 145 ? -65.184  -95.810  25.818  1.00 22.40  ? 145  TYR D O     1 
ATOM   11034 C CB    . TYR D 1 145 ? -67.940  -95.574  23.810  1.00 19.44  ? 145  TYR D CB    1 
ATOM   11035 C CG    . TYR D 1 145 ? -67.252  -96.683  23.032  1.00 20.20  ? 145  TYR D CG    1 
ATOM   11036 C CD1   . TYR D 1 145 ? -67.708  -97.993  23.085  1.00 18.12  ? 145  TYR D CD1   1 
ATOM   11037 C CD2   . TYR D 1 145 ? -66.169  -96.408  22.198  1.00 19.89  ? 145  TYR D CD2   1 
ATOM   11038 C CE1   . TYR D 1 145 ? -67.103  -98.995  22.339  1.00 19.60  ? 145  TYR D CE1   1 
ATOM   11039 C CE2   . TYR D 1 145 ? -65.555  -97.408  21.451  1.00 20.04  ? 145  TYR D CE2   1 
ATOM   11040 C CZ    . TYR D 1 145 ? -66.040  -98.701  21.506  1.00 20.32  ? 145  TYR D CZ    1 
ATOM   11041 O OH    . TYR D 1 145 ? -65.457  -99.682  20.756  1.00 21.26  ? 145  TYR D OH    1 
ATOM   11042 N N     . LEU D 1 146 ? -65.529  -93.867  24.737  1.00 20.10  ? 146  LEU D N     1 
ATOM   11043 C CA    . LEU D 1 146 ? -64.128  -93.479  24.752  1.00 21.95  ? 146  LEU D CA    1 
ATOM   11044 C C     . LEU D 1 146 ? -63.650  -93.420  26.210  1.00 25.16  ? 146  LEU D C     1 
ATOM   11045 O O     . LEU D 1 146 ? -62.662  -94.064  26.579  1.00 23.08  ? 146  LEU D O     1 
ATOM   11046 C CB    . LEU D 1 146 ? -63.927  -92.155  24.028  1.00 20.12  ? 146  LEU D CB    1 
ATOM   11047 C CG    . LEU D 1 146 ? -62.548  -91.504  24.176  1.00 21.34  ? 146  LEU D CG    1 
ATOM   11048 C CD1   . LEU D 1 146 ? -61.429  -92.384  23.631  1.00 20.74  ? 146  LEU D CD1   1 
ATOM   11049 C CD2   . LEU D 1 146 ? -62.575  -90.148  23.463  1.00 21.42  ? 146  LEU D CD2   1 
ATOM   11050 N N     . GLN D 1 147 ? -64.427  -92.713  27.047  1.00 22.94  ? 147  GLN D N     1 
ATOM   11051 C CA    . GLN D 1 147 ? -64.078  -92.569  28.448  1.00 21.32  ? 147  GLN D CA    1 
ATOM   11052 C C     . GLN D 1 147 ? -64.001  -93.918  29.170  1.00 22.31  ? 147  GLN D C     1 
ATOM   11053 O O     . GLN D 1 147 ? -63.091  -94.144  29.962  1.00 22.18  ? 147  GLN D O     1 
ATOM   11054 C CB    . GLN D 1 147 ? -65.025  -91.607  29.150  1.00 22.60  ? 147  GLN D CB    1 
ATOM   11055 C CG    . GLN D 1 147 ? -64.608  -91.409  30.596  1.00 23.99  ? 147  GLN D CG    1 
ATOM   11056 C CD    . GLN D 1 147 ? -65.241  -90.211  31.247  1.00 29.68  ? 147  GLN D CD    1 
ATOM   11057 O OE1   . GLN D 1 147 ? -65.378  -89.119  30.664  1.00 29.38  ? 147  GLN D OE1   1 
ATOM   11058 N NE2   . GLN D 1 147 ? -65.604  -90.455  32.493  1.00 28.41  ? 147  GLN D NE2   1 
ATOM   11059 N N     . LYS D 1 148 ? -64.916  -94.835  28.859  1.00 21.69  ? 148  LYS D N     1 
ATOM   11060 C CA    . LYS D 1 148 ? -64.910  -96.137  29.491  1.00 24.36  ? 148  LYS D CA    1 
ATOM   11061 C C     . LYS D 1 148 ? -63.662  -96.913  29.068  1.00 23.27  ? 148  LYS D C     1 
ATOM   11062 O O     . LYS D 1 148 ? -63.039  -97.614  29.882  1.00 24.75  ? 148  LYS D O     1 
ATOM   11063 C CB    . LYS D 1 148 ? -66.209  -96.859  29.106  1.00 30.43  ? 148  LYS D CB    1 
ATOM   11064 C CG    . LYS D 1 148 ? -66.423  -98.186  29.816  1.00 39.21  ? 148  LYS D CG    1 
ATOM   11065 C CD    . LYS D 1 148 ? -67.128  -97.891  31.120  1.00 51.65  ? 148  LYS D CD    1 
ATOM   11066 C CE    . LYS D 1 148 ? -66.786  -98.803  32.260  1.00 60.61  ? 148  LYS D CE    1 
ATOM   11067 N NZ    . LYS D 1 148 ? -67.511  -98.237  33.399  1.00 69.77  ? 148  LYS D NZ    1 
ATOM   11068 N N     . SER D 1 149 ? -63.293  -96.799  27.787  1.00 22.24  ? 149  SER D N     1 
ATOM   11069 C CA    . SER D 1 149 ? -62.132  -97.530  27.281  1.00 22.07  ? 149  SER D CA    1 
ATOM   11070 C C     . SER D 1 149 ? -60.857  -97.015  27.961  1.00 22.02  ? 149  SER D C     1 
ATOM   11071 O O     . SER D 1 149 ? -59.965  -97.796  28.270  1.00 23.21  ? 149  SER D O     1 
ATOM   11072 C CB    . SER D 1 149 ? -62.046  -97.528  25.777  1.00 19.73  ? 149  SER D CB    1 
ATOM   11073 O OG    . SER D 1 149 ? -61.635  -96.255  25.328  1.00 22.79  ? 149  SER D OG    1 
ATOM   11074 N N     . VAL D 1 150 ? -60.816  -95.716  28.283  1.00 19.63  ? 150  VAL D N     1 
ATOM   11075 C CA    . VAL D 1 150 ? -59.680  -95.161  29.001  1.00 20.68  ? 150  VAL D CA    1 
ATOM   11076 C C     . VAL D 1 150 ? -59.711  -95.565  30.479  1.00 22.08  ? 150  VAL D C     1 
ATOM   11077 O O     . VAL D 1 150 ? -58.667  -95.793  31.100  1.00 20.07  ? 150  VAL D O     1 
ATOM   11078 C CB    . VAL D 1 150 ? -59.624  -93.631  28.811  1.00 20.17  ? 150  VAL D CB    1 
ATOM   11079 C CG1   . VAL D 1 150 ? -58.553  -92.989  29.688  1.00 18.13  ? 150  VAL D CG1   1 
ATOM   11080 C CG2   . VAL D 1 150 ? -59.413  -93.283  27.338  1.00 18.22  ? 150  VAL D CG2   1 
ATOM   11081 N N     . GLU D 1 151 ? -60.919  -95.652  31.043  1.00 22.79  ? 151  GLU D N     1 
ATOM   11082 C CA    . GLU D 1 151 ? -61.094  -96.057  32.424  1.00 22.15  ? 151  GLU D CA    1 
ATOM   11083 C C     . GLU D 1 151 ? -60.530  -97.456  32.655  1.00 24.04  ? 151  GLU D C     1 
ATOM   11084 O O     . GLU D 1 151 ? -59.857  -97.687  33.654  1.00 23.23  ? 151  GLU D O     1 
ATOM   11085 C CB    . GLU D 1 151 ? -62.559  -95.916  32.822  1.00 25.01  ? 151  GLU D CB    1 
ATOM   11086 C CG    . GLU D 1 151 ? -62.824  -96.296  34.278  1.00 31.58  ? 151  GLU D CG    1 
ATOM   11087 C CD    . GLU D 1 151 ? -64.299  -96.491  34.626  1.00 42.66  ? 151  GLU D CD    1 
ATOM   11088 O OE1   . GLU D 1 151 ? -65.218  -96.111  33.856  1.00 48.28  ? 151  GLU D OE1   1 
ATOM   11089 O OE2   . GLU D 1 151 ? -64.526  -96.997  35.729  1.00 47.13  ? 151  GLU D OE2   1 
ATOM   11090 N N     . VAL D 1 152 ? -60.775  -98.380  31.717  1.00 22.68  ? 152  VAL D N     1 
ATOM   11091 C CA    . VAL D 1 152 ? -60.206  -99.705  31.843  1.00 22.11  ? 152  VAL D CA    1 
ATOM   11092 C C     . VAL D 1 152 ? -58.670  -99.622  31.943  1.00 27.13  ? 152  VAL D C     1 
ATOM   11093 O O     . VAL D 1 152 ? -58.063  -100.324 32.758  1.00 25.89  ? 152  VAL D O     1 
ATOM   11094 C CB    . VAL D 1 152 ? -60.656  -100.609 30.689  1.00 23.63  ? 152  VAL D CB    1 
ATOM   11095 C CG1   . VAL D 1 152 ? -59.881  -101.926 30.636  1.00 19.55  ? 152  VAL D CG1   1 
ATOM   11096 C CG2   . VAL D 1 152 ? -62.165  -100.841 30.775  1.00 22.81  ? 152  VAL D CG2   1 
ATOM   11097 N N     . LEU D 1 153 ? -58.049  -98.760  31.125  1.00 24.32  ? 153  LEU D N     1 
ATOM   11098 C CA    . LEU D 1 153 ? -56.595  -98.639  31.114  1.00 23.90  ? 153  LEU D CA    1 
ATOM   11099 C C     . LEU D 1 153 ? -56.129  -98.035  32.440  1.00 24.15  ? 153  LEU D C     1 
ATOM   11100 O O     . LEU D 1 153 ? -55.040  -98.335  32.887  1.00 21.00  ? 153  LEU D O     1 
ATOM   11101 C CB    . LEU D 1 153 ? -56.079  -97.827  29.919  1.00 19.88  ? 153  LEU D CB    1 
ATOM   11102 C CG    . LEU D 1 153 ? -56.265  -98.525  28.562  1.00 20.46  ? 153  LEU D CG    1 
ATOM   11103 C CD1   . LEU D 1 153 ? -56.056  -97.514  27.443  1.00 18.12  ? 153  LEU D CD1   1 
ATOM   11104 C CD2   . LEU D 1 153 ? -55.377  -99.736  28.402  1.00 16.37  ? 153  LEU D CD2   1 
ATOM   11105 N N     . CYS D 1 154 ? -56.957  -97.171  33.046  1.00 21.57  ? 154  CYS D N     1 
ATOM   11106 C CA    . CYS D 1 154 ? -56.597  -96.518  34.294  1.00 22.18  ? 154  CYS D CA    1 
ATOM   11107 C C     . CYS D 1 154 ? -56.771  -97.433  35.520  1.00 26.35  ? 154  CYS D C     1 
ATOM   11108 O O     . CYS D 1 154 ? -56.248  -97.118  36.580  1.00 22.46  ? 154  CYS D O     1 
ATOM   11109 C CB    . CYS D 1 154 ? -57.488  -95.322  34.577  1.00 20.41  ? 154  CYS D CB    1 
ATOM   11110 S SG    . CYS D 1 154 ? -57.095  -93.953  33.451  1.00 23.29  ? 154  CYS D SG    1 
ATOM   11111 N N     . ARG D 1 155 ? -57.471  -98.568  35.385  1.00 24.31  ? 155  ARG D N     1 
ATOM   11112 C CA    . ARG D 1 155 ? -57.918  -99.291  36.573  1.00 28.01  ? 155  ARG D CA    1 
ATOM   11113 C C     . ARG D 1 155 ? -57.453  -100.745 36.619  1.00 27.14  ? 155  ARG D C     1 
ATOM   11114 O O     . ARG D 1 155 ? -57.639  -101.372 37.640  1.00 26.74  ? 155  ARG D O     1 
ATOM   11115 C CB    . ARG D 1 155 ? -59.453  -99.315  36.670  1.00 24.89  ? 155  ARG D CB    1 
ATOM   11116 C CG    . ARG D 1 155 ? -59.940  -97.909  36.938  1.00 27.78  ? 155  ARG D CG    1 
ATOM   11117 C CD    . ARG D 1 155 ? -61.421  -97.937  37.192  1.00 27.99  ? 155  ARG D CD    1 
ATOM   11118 N NE    . ARG D 1 155 ? -61.769  -98.689  38.400  1.00 31.60  ? 155  ARG D NE    1 
ATOM   11119 C CZ    . ARG D 1 155 ? -63.000  -99.009  38.765  1.00 35.66  ? 155  ARG D CZ    1 
ATOM   11120 N NH1   . ARG D 1 155 ? -64.054  -98.622  38.058  1.00 35.54  ? 155  ARG D NH1   1 
ATOM   11121 N NH2   . ARG D 1 155 ? -63.211  -99.677  39.877  1.00 31.17  ? 155  ARG D NH2   1 
ATOM   11122 N N     . ASN D 1 156 ? -56.849  -101.269 35.541  1.00 23.94  ? 156  ASN D N     1 
ATOM   11123 C CA    . ASN D 1 156 ? -56.568  -102.685 35.525  1.00 23.66  ? 156  ASN D CA    1 
ATOM   11124 C C     . ASN D 1 156 ? -55.079  -103.005 35.460  1.00 25.24  ? 156  ASN D C     1 
ATOM   11125 O O     . ASN D 1 156 ? -54.758  -104.178 35.300  1.00 24.60  ? 156  ASN D O     1 
ATOM   11126 C CB    . ASN D 1 156 ? -57.340  -103.364 34.398  1.00 25.82  ? 156  ASN D CB    1 
ATOM   11127 C CG    . ASN D 1 156 ? -58.820  -103.447 34.732  1.00 26.69  ? 156  ASN D CG    1 
ATOM   11128 O OD1   . ASN D 1 156 ? -59.269  -104.368 35.390  1.00 36.71  ? 156  ASN D OD1   1 
ATOM   11129 N ND2   . ASN D 1 156 ? -59.595  -102.444 34.425  1.00 28.28  ? 156  ASN D ND2   1 
ATOM   11130 N N     . TYR D 1 157 ? -54.181  -102.014 35.570  1.00 25.85  ? 157  TYR D N     1 
ATOM   11131 C CA    . TYR D 1 157 ? -52.782  -102.290 35.228  1.00 25.33  ? 157  TYR D CA    1 
ATOM   11132 C C     . TYR D 1 157 ? -51.814  -101.729 36.283  1.00 22.93  ? 157  TYR D C     1 
ATOM   11133 O O     . TYR D 1 157 ? -50.589  -101.841 36.124  1.00 25.82  ? 157  TYR D O     1 
ATOM   11134 C CB    . TYR D 1 157 ? -52.469  -101.816 33.797  1.00 22.17  ? 157  TYR D CB    1 
ATOM   11135 C CG    . TYR D 1 157 ? -53.407  -102.465 32.790  1.00 20.81  ? 157  TYR D CG    1 
ATOM   11136 C CD1   . TYR D 1 157 ? -53.202  -103.791 32.400  1.00 21.46  ? 157  TYR D CD1   1 
ATOM   11137 C CD2   . TYR D 1 157 ? -54.530  -101.783 32.289  1.00 20.29  ? 157  TYR D CD2   1 
ATOM   11138 C CE1   . TYR D 1 157 ? -54.054  -104.423 31.498  1.00 22.05  ? 157  TYR D CE1   1 
ATOM   11139 C CE2   . TYR D 1 157 ? -55.368  -102.412 31.377  1.00 21.59  ? 157  TYR D CE2   1 
ATOM   11140 C CZ    . TYR D 1 157 ? -55.145  -103.728 30.988  1.00 21.62  ? 157  TYR D CZ    1 
ATOM   11141 O OH    . TYR D 1 157 ? -56.025  -104.374 30.133  1.00 22.47  ? 157  TYR D OH    1 
ATOM   11142 N N     . GLY D 1 158 ? -52.320  -101.057 37.288  1.00 19.81  ? 158  GLY D N     1 
ATOM   11143 C CA    . GLY D 1 158 ? -51.495  -100.386 38.253  1.00 20.22  ? 158  GLY D CA    1 
ATOM   11144 C C     . GLY D 1 158 ? -51.078  -99.019  37.753  1.00 22.76  ? 158  GLY D C     1 
ATOM   11145 O O     . GLY D 1 158 ? -51.562  -98.528  36.789  1.00 23.17  ? 158  GLY D O     1 
ATOM   11146 N N     . PRO D 1 159 ? -50.119  -98.406  38.407  1.00 22.15  ? 159  PRO D N     1 
ATOM   11147 C CA    . PRO D 1 159 ? -49.636  -97.097  37.986  1.00 22.82  ? 159  PRO D CA    1 
ATOM   11148 C C     . PRO D 1 159 ? -49.049  -97.086  36.551  1.00 24.92  ? 159  PRO D C     1 
ATOM   11149 O O     . PRO D 1 159 ? -48.265  -97.874  36.133  1.00 23.88  ? 159  PRO D O     1 
ATOM   11150 C CB    . PRO D 1 159 ? -48.596  -96.778  39.024  1.00 19.86  ? 159  PRO D CB    1 
ATOM   11151 C CG    . PRO D 1 159 ? -48.907  -97.634  40.148  1.00 18.92  ? 159  PRO D CG    1 
ATOM   11152 C CD    . PRO D 1 159 ? -49.470  -98.863  39.620  1.00 18.74  ? 159  PRO D CD    1 
ATOM   11153 N N     . VAL D 1 160 ? -49.446  -96.085  35.822  1.00 24.74  ? 160  VAL D N     1 
ATOM   11154 C CA    . VAL D 1 160 ? -49.142  -95.947  34.434  1.00 29.88  ? 160  VAL D CA    1 
ATOM   11155 C C     . VAL D 1 160 ? -48.324  -94.700  34.158  1.00 28.10  ? 160  VAL D C     1 
ATOM   11156 O O     . VAL D 1 160 ? -48.461  -93.727  34.818  1.00 27.65  ? 160  VAL D O     1 
ATOM   11157 C CB    . VAL D 1 160 ? -50.501  -95.917  33.701  1.00 34.56  ? 160  VAL D CB    1 
ATOM   11158 C CG1   . VAL D 1 160 ? -50.467  -95.280  32.354  1.00 38.80  ? 160  VAL D CG1   1 
ATOM   11159 C CG2   . VAL D 1 160 ? -51.107  -97.263  33.624  1.00 38.32  ? 160  VAL D CG2   1 
ATOM   11160 N N     . GLY D 1 161 ? -47.387  -94.776  33.246  1.00 23.99  ? 161  GLY D N     1 
ATOM   11161 C CA    . GLY D 1 161 ? -46.606  -93.615  32.907  1.00 21.91  ? 161  GLY D CA    1 
ATOM   11162 C C     . GLY D 1 161 ? -47.349  -92.462  32.269  1.00 22.52  ? 161  GLY D C     1 
ATOM   11163 O O     . GLY D 1 161 ? -47.171  -91.354  32.599  1.00 22.77  ? 161  GLY D O     1 
ATOM   11164 N N     . GLY D 1 162 ? -48.234  -92.746  31.368  1.00 20.62  ? 162  GLY D N     1 
ATOM   11165 C CA    . GLY D 1 162 ? -48.930  -91.659  30.687  1.00 20.52  ? 162  GLY D CA    1 
ATOM   11166 C C     . GLY D 1 162 ? -49.870  -92.163  29.598  1.00 21.41  ? 162  GLY D C     1 
ATOM   11167 O O     . GLY D 1 162 ? -49.930  -93.366  29.309  1.00 18.59  ? 162  GLY D O     1 
ATOM   11168 N N     . PHE D 1 163 ? -50.618  -91.216  29.029  1.00 22.63  ? 163  PHE D N     1 
ATOM   11169 C CA    . PHE D 1 163 ? -51.615  -91.427  27.989  1.00 18.88  ? 163  PHE D CA    1 
ATOM   11170 C C     . PHE D 1 163 ? -51.280  -90.441  26.889  1.00 20.60  ? 163  PHE D C     1 
ATOM   11171 O O     . PHE D 1 163 ? -50.841  -89.308  27.160  1.00 22.43  ? 163  PHE D O     1 
ATOM   11172 C CB    . PHE D 1 163 ? -53.021  -91.075  28.489  1.00 18.43  ? 163  PHE D CB    1 
ATOM   11173 C CG    . PHE D 1 163 ? -53.535  -92.096  29.500  1.00 20.36  ? 163  PHE D CG    1 
ATOM   11174 C CD1   . PHE D 1 163 ? -54.237  -93.218  29.061  1.00 18.35  ? 163  PHE D CD1   1 
ATOM   11175 C CD2   . PHE D 1 163 ? -53.244  -91.980  30.868  1.00 20.39  ? 163  PHE D CD2   1 
ATOM   11176 C CE1   . PHE D 1 163 ? -54.722  -94.157  29.964  1.00 21.13  ? 163  PHE D CE1   1 
ATOM   11177 C CE2   . PHE D 1 163 ? -53.651  -92.966  31.762  1.00 22.31  ? 163  PHE D CE2   1 
ATOM   11178 C CZ    . PHE D 1 163 ? -54.387  -94.066  31.296  1.00 21.81  ? 163  PHE D CZ    1 
ATOM   11179 N N     . TRP D 1 164 ? -51.462  -90.898  25.646  1.00 21.02  ? 164  TRP D N     1 
ATOM   11180 C CA    . TRP D 1 164 ? -51.093  -90.147  24.463  1.00 20.31  ? 164  TRP D CA    1 
ATOM   11181 C C     . TRP D 1 164 ? -52.346  -90.137  23.586  1.00 21.55  ? 164  TRP D C     1 
ATOM   11182 O O     . TRP D 1 164 ? -52.712  -91.148  22.975  1.00 20.11  ? 164  TRP D O     1 
ATOM   11183 C CB    . TRP D 1 164 ? -49.888  -90.838  23.798  1.00 17.82  ? 164  TRP D CB    1 
ATOM   11184 C CG    . TRP D 1 164 ? -48.985  -89.962  22.959  1.00 19.10  ? 164  TRP D CG    1 
ATOM   11185 C CD1   . TRP D 1 164 ? -47.763  -89.474  23.326  1.00 19.65  ? 164  TRP D CD1   1 
ATOM   11186 C CD2   . TRP D 1 164 ? -49.189  -89.524  21.590  1.00 20.19  ? 164  TRP D CD2   1 
ATOM   11187 N NE1   . TRP D 1 164 ? -47.203  -88.756  22.303  1.00 19.61  ? 164  TRP D NE1   1 
ATOM   11188 C CE2   . TRP D 1 164 ? -48.031  -88.778  21.215  1.00 19.25  ? 164  TRP D CE2   1 
ATOM   11189 C CE3   . TRP D 1 164 ? -50.219  -89.698  20.641  1.00 20.01  ? 164  TRP D CE3   1 
ATOM   11190 C CZ2   . TRP D 1 164 ? -47.866  -88.217  19.943  1.00 17.66  ? 164  TRP D CZ2   1 
ATOM   11191 C CZ3   . TRP D 1 164 ? -50.049  -89.148  19.371  1.00 21.63  ? 164  TRP D CZ3   1 
ATOM   11192 C CH2   . TRP D 1 164 ? -48.888  -88.416  19.020  1.00 20.00  ? 164  TRP D CH2   1 
ATOM   11193 N N     . PHE D 1 165 ? -53.044  -88.999  23.588  1.00 19.62  ? 165  PHE D N     1 
ATOM   11194 C CA    . PHE D 1 165 ? -54.355  -88.901  22.969  1.00 19.31  ? 165  PHE D CA    1 
ATOM   11195 C C     . PHE D 1 165 ? -54.213  -88.327  21.568  1.00 22.61  ? 165  PHE D C     1 
ATOM   11196 O O     . PHE D 1 165 ? -53.596  -87.278  21.389  1.00 22.36  ? 165  PHE D O     1 
ATOM   11197 C CB    . PHE D 1 165 ? -55.353  -88.058  23.761  1.00 16.90  ? 165  PHE D CB    1 
ATOM   11198 C CG    . PHE D 1 165 ? -55.825  -88.832  24.983  1.00 19.42  ? 165  PHE D CG    1 
ATOM   11199 C CD1   . PHE D 1 165 ? -56.662  -89.937  24.828  1.00 19.72  ? 165  PHE D CD1   1 
ATOM   11200 C CD2   . PHE D 1 165 ? -55.448  -88.447  26.278  1.00 19.23  ? 165  PHE D CD2   1 
ATOM   11201 C CE1   . PHE D 1 165 ? -57.106  -90.640  25.946  1.00 20.61  ? 165  PHE D CE1   1 
ATOM   11202 C CE2   . PHE D 1 165 ? -55.857  -89.169  27.389  1.00 18.20  ? 165  PHE D CE2   1 
ATOM   11203 C CZ    . PHE D 1 165 ? -56.677  -90.263  27.225  1.00 19.29  ? 165  PHE D CZ    1 
ATOM   11204 N N     . ASP D 1 166 ? -54.845  -88.992  20.597  1.00 23.39  ? 166  ASP D N     1 
ATOM   11205 C CA    . ASP D 1 166 ? -54.753  -88.509  19.238  1.00 25.28  ? 166  ASP D CA    1 
ATOM   11206 C C     . ASP D 1 166 ? -56.122  -88.464  18.560  1.00 27.31  ? 166  ASP D C     1 
ATOM   11207 O O     . ASP D 1 166 ? -56.757  -89.509  18.420  1.00 29.55  ? 166  ASP D O     1 
ATOM   11208 C CB    . ASP D 1 166 ? -53.815  -89.440  18.505  1.00 26.27  ? 166  ASP D CB    1 
ATOM   11209 C CG    . ASP D 1 166 ? -53.739  -89.192  17.006  1.00 27.77  ? 166  ASP D CG    1 
ATOM   11210 O OD1   . ASP D 1 166 ? -53.695  -87.997  16.629  1.00 26.02  ? 166  ASP D OD1   1 
ATOM   11211 O OD2   . ASP D 1 166 ? -53.725  -90.182  16.248  1.00 28.91  ? 166  ASP D OD2   1 
ATOM   11212 N N     . GLY D 1 167 ? -56.569  -87.290  18.084  1.00 34.05  ? 167  GLY D N     1 
ATOM   11213 C CA    . GLY D 1 167 ? -57.647  -87.363  17.091  1.00 38.67  ? 167  GLY D CA    1 
ATOM   11214 C C     . GLY D 1 167 ? -58.823  -86.398  17.305  1.00 43.19  ? 167  GLY D C     1 
ATOM   11215 O O     . GLY D 1 167 ? -59.808  -86.413  16.547  1.00 39.35  ? 167  GLY D O     1 
ATOM   11216 N N     . ASN D 1 168 ? -58.729  -85.558  18.347  1.00 39.96  ? 168  ASN D N     1 
ATOM   11217 C CA    . ASN D 1 168 ? -59.738  -84.531  18.582  1.00 36.39  ? 168  ASN D CA    1 
ATOM   11218 C C     . ASN D 1 168 ? -59.788  -83.571  17.389  1.00 40.37  ? 168  ASN D C     1 
ATOM   11219 O O     . ASN D 1 168 ? -60.827  -82.970  17.141  1.00 35.97  ? 168  ASN D O     1 
ATOM   11220 C CB    . ASN D 1 168 ? -59.542  -83.800  19.908  1.00 33.62  ? 168  ASN D CB    1 
ATOM   11221 C CG    . ASN D 1 168 ? -59.788  -84.650  21.147  1.00 35.44  ? 168  ASN D CG    1 
ATOM   11222 O OD1   . ASN D 1 168 ? -59.918  -84.101  22.243  1.00 38.56  ? 168  ASN D OD1   1 
ATOM   11223 N ND2   . ASN D 1 168 ? -59.860  -85.977  21.034  1.00 34.03  ? 168  ASN D ND2   1 
ATOM   11224 N N     . TRP D 1 169 ? -58.672  -83.482  16.639  1.00 36.35  ? 169  TRP D N     1 
ATOM   11225 C CA    . TRP D 1 169 ? -58.543  -82.681  15.426  1.00 38.30  ? 169  TRP D CA    1 
ATOM   11226 C C     . TRP D 1 169 ? -59.570  -83.088  14.359  1.00 38.65  ? 169  TRP D C     1 
ATOM   11227 O O     . TRP D 1 169 ? -59.804  -82.324  13.429  1.00 39.53  ? 169  TRP D O     1 
ATOM   11228 C CB    . TRP D 1 169 ? -57.101  -82.757  14.868  1.00 38.03  ? 169  TRP D CB    1 
ATOM   11229 C CG    . TRP D 1 169 ? -56.515  -84.151  14.891  1.00 41.32  ? 169  TRP D CG    1 
ATOM   11230 C CD1   . TRP D 1 169 ? -55.625  -84.653  15.802  1.00 34.23  ? 169  TRP D CD1   1 
ATOM   11231 C CD2   . TRP D 1 169 ? -56.831  -85.245  13.988  1.00 37.91  ? 169  TRP D CD2   1 
ATOM   11232 N NE1   . TRP D 1 169 ? -55.356  -85.970  15.523  1.00 30.11  ? 169  TRP D NE1   1 
ATOM   11233 C CE2   . TRP D 1 169 ? -56.066  -86.360  14.417  1.00 34.84  ? 169  TRP D CE2   1 
ATOM   11234 C CE3   . TRP D 1 169 ? -57.665  -85.375  12.865  1.00 33.25  ? 169  TRP D CE3   1 
ATOM   11235 C CZ2   . TRP D 1 169 ? -56.112  -87.591  13.761  1.00 33.17  ? 169  TRP D CZ2   1 
ATOM   11236 C CZ3   . TRP D 1 169 ? -57.721  -86.589  12.217  1.00 40.03  ? 169  TRP D CZ3   1 
ATOM   11237 C CH2   . TRP D 1 169 ? -56.954  -87.679  12.665  1.00 41.56  ? 169  TRP D CH2   1 
ATOM   11238 N N     . ASN D 1 170 ? -60.178  -84.283  14.477  1.00 38.29  ? 170  ASN D N     1 
ATOM   11239 C CA    . ASN D 1 170 ? -61.169  -84.707  13.501  1.00 33.23  ? 170  ASN D CA    1 
ATOM   11240 C C     . ASN D 1 170 ? -62.467  -83.885  13.631  1.00 33.76  ? 170  ASN D C     1 
ATOM   11241 O O     . ASN D 1 170 ? -63.168  -83.673  12.654  1.00 36.52  ? 170  ASN D O     1 
ATOM   11242 C CB    . ASN D 1 170 ? -61.429  -86.201  13.553  1.00 33.86  ? 170  ASN D CB    1 
ATOM   11243 C CG    . ASN D 1 170 ? -62.577  -86.579  12.631  1.00 40.13  ? 170  ASN D CG    1 
ATOM   11244 O OD1   . ASN D 1 170 ? -63.732  -86.821  13.052  1.00 37.30  ? 170  ASN D OD1   1 
ATOM   11245 N ND2   . ASN D 1 170 ? -62.301  -86.578  11.343  1.00 32.40  ? 170  ASN D ND2   1 
ATOM   11246 N N     . LYS D 1 171 ? -62.826  -83.453  14.839  1.00 36.28  ? 171  LYS D N     1 
ATOM   11247 C CA    . LYS D 1 171 ? -63.968  -82.573  15.070  1.00 38.26  ? 171  LYS D CA    1 
ATOM   11248 C C     . LYS D 1 171 ? -63.515  -81.388  15.936  1.00 42.45  ? 171  LYS D C     1 
ATOM   11249 O O     . LYS D 1 171 ? -63.662  -81.425  17.165  1.00 38.91  ? 171  LYS D O     1 
ATOM   11250 C CB    . LYS D 1 171 ? -65.093  -83.329  15.799  1.00 34.86  ? 171  LYS D CB    1 
ATOM   11251 C CG    . LYS D 1 171 ? -65.749  -84.486  15.049  1.00 35.35  ? 171  LYS D CG    1 
ATOM   11252 C CD    . LYS D 1 171 ? -66.826  -85.243  15.809  1.00 38.62  ? 171  LYS D CD    1 
ATOM   11253 C CE    . LYS D 1 171 ? -67.855  -85.645  14.796  1.00 56.61  ? 171  LYS D CE    1 
ATOM   11254 N NZ    . LYS D 1 171 ? -68.662  -86.855  15.014  1.00 53.59  ? 171  LYS D NZ    1 
ATOM   11255 N N     . LYS D 1 172 ? -62.923  -80.361  15.299  1.00 51.12  ? 172  LYS D N     1 
ATOM   11256 C CA    . LYS D 1 172 ? -62.278  -79.264  16.015  1.00 58.07  ? 172  LYS D CA    1 
ATOM   11257 C C     . LYS D 1 172 ? -63.278  -78.463  16.847  1.00 57.91  ? 172  LYS D C     1 
ATOM   11258 O O     . LYS D 1 172 ? -62.889  -77.848  17.838  1.00 52.58  ? 172  LYS D O     1 
ATOM   11259 C CB    . LYS D 1 172 ? -61.438  -78.334  15.127  1.00 63.50  ? 172  LYS D CB    1 
ATOM   11260 C CG    . LYS D 1 172 ? -60.159  -78.964  14.593  1.00 85.98  ? 172  LYS D CG    1 
ATOM   11261 C CD    . LYS D 1 172 ? -58.987  -78.021  14.306  1.00 102.83 ? 172  LYS D CD    1 
ATOM   11262 C CE    . LYS D 1 172 ? -57.742  -78.790  13.985  1.00 98.76  ? 172  LYS D CE    1 
ATOM   11263 N NZ    . LYS D 1 172 ? -57.905  -79.474  12.698  1.00 83.78  ? 172  LYS D NZ    1 
ATOM   11264 N N     . ASP D 1 173 ? -64.554  -78.487  16.443  1.00 56.65  ? 173  ASP D N     1 
ATOM   11265 C CA    . ASP D 1 173 ? -65.593  -77.648  17.036  1.00 58.06  ? 173  ASP D CA    1 
ATOM   11266 C C     . ASP D 1 173 ? -66.362  -78.332  18.172  1.00 53.42  ? 173  ASP D C     1 
ATOM   11267 O O     . ASP D 1 173 ? -67.023  -77.642  18.942  1.00 45.79  ? 173  ASP D O     1 
ATOM   11268 C CB    . ASP D 1 173 ? -66.449  -76.978  15.966  1.00 59.90  ? 173  ASP D CB    1 
ATOM   11269 C CG    . ASP D 1 173 ? -65.705  -75.899  15.185  1.00 69.79  ? 173  ASP D CG    1 
ATOM   11270 O OD1   . ASP D 1 173 ? -64.682  -75.383  15.717  1.00 60.81  ? 173  ASP D OD1   1 
ATOM   11271 O OD2   . ASP D 1 173 ? -66.098  -75.633  14.030  1.00 70.32  ? 173  ASP D OD2   1 
ATOM   11272 N N     . ALA D 1 174 ? -66.278  -79.666  18.288  1.00 42.18  ? 174  ALA D N     1 
ATOM   11273 C CA    . ALA D 1 174 ? -67.137  -80.419  19.194  1.00 37.35  ? 174  ALA D CA    1 
ATOM   11274 C C     . ALA D 1 174 ? -66.732  -80.216  20.652  1.00 35.35  ? 174  ALA D C     1 
ATOM   11275 O O     . ALA D 1 174 ? -65.603  -79.841  20.948  1.00 33.25  ? 174  ALA D O     1 
ATOM   11276 C CB    . ALA D 1 174 ? -67.138  -81.881  18.821  1.00 32.22  ? 174  ALA D CB    1 
ATOM   11277 N N     . ASP D 1 175 ? -67.672  -80.472  21.557  1.00 33.10  ? 175  ASP D N     1 
ATOM   11278 C CA    . ASP D 1 175 ? -67.372  -80.544  22.973  1.00 34.21  ? 175  ASP D CA    1 
ATOM   11279 C C     . ASP D 1 175 ? -66.924  -81.972  23.279  1.00 29.00  ? 175  ASP D C     1 
ATOM   11280 O O     . ASP D 1 175 ? -67.732  -82.893  23.205  1.00 29.02  ? 175  ASP D O     1 
ATOM   11281 C CB    . ASP D 1 175 ? -68.561  -80.092  23.814  1.00 31.98  ? 175  ASP D CB    1 
ATOM   11282 C CG    . ASP D 1 175 ? -68.341  -80.036  25.325  1.00 40.47  ? 175  ASP D CG    1 
ATOM   11283 O OD1   . ASP D 1 175 ? -67.282  -80.497  25.806  1.00 40.97  ? 175  ASP D OD1   1 
ATOM   11284 O OD2   . ASP D 1 175 ? -69.216  -79.494  26.029  1.00 48.20  ? 175  ASP D OD2   1 
ATOM   11285 N N     . TRP D 1 176 ? -65.640  -82.137  23.627  1.00 26.70  ? 176  TRP D N     1 
ATOM   11286 C CA    . TRP D 1 176 ? -65.071  -83.459  23.865  1.00 26.76  ? 176  TRP D CA    1 
ATOM   11287 C C     . TRP D 1 176 ? -65.149  -83.842  25.345  1.00 25.45  ? 176  TRP D C     1 
ATOM   11288 O O     . TRP D 1 176 ? -64.743  -84.941  25.705  1.00 27.21  ? 176  TRP D O     1 
ATOM   11289 C CB    . TRP D 1 176 ? -63.623  -83.553  23.347  1.00 25.43  ? 176  TRP D CB    1 
ATOM   11290 C CG    . TRP D 1 176 ? -63.532  -83.709  21.848  1.00 25.66  ? 176  TRP D CG    1 
ATOM   11291 C CD1   . TRP D 1 176 ? -63.476  -82.705  20.921  1.00 22.85  ? 176  TRP D CD1   1 
ATOM   11292 C CD2   . TRP D 1 176 ? -63.462  -84.953  21.100  1.00 20.67  ? 176  TRP D CD2   1 
ATOM   11293 N NE1   . TRP D 1 176 ? -63.393  -83.235  19.650  1.00 22.10  ? 176  TRP D NE1   1 
ATOM   11294 C CE2   . TRP D 1 176 ? -63.368  -84.606  19.731  1.00 21.07  ? 176  TRP D CE2   1 
ATOM   11295 C CE3   . TRP D 1 176 ? -63.438  -86.299  21.458  1.00 17.79  ? 176  TRP D CE3   1 
ATOM   11296 C CZ2   . TRP D 1 176 ? -63.273  -85.563  18.721  1.00 20.29  ? 176  TRP D CZ2   1 
ATOM   11297 C CZ3   . TRP D 1 176 ? -63.334  -87.246  20.464  1.00 20.11  ? 176  TRP D CZ3   1 
ATOM   11298 C CH2   . TRP D 1 176 ? -63.246  -86.880  19.114  1.00 19.95  ? 176  TRP D CH2   1 
ATOM   11299 N N     . HIS D 1 177 ? -65.651  -82.942  26.199  1.00 26.50  ? 177  HIS D N     1 
ATOM   11300 C CA    . HIS D 1 177 ? -65.841  -83.258  27.612  1.00 28.78  ? 177  HIS D CA    1 
ATOM   11301 C C     . HIS D 1 177 ? -64.501  -83.697  28.218  1.00 29.11  ? 177  HIS D C     1 
ATOM   11302 O O     . HIS D 1 177 ? -64.386  -84.740  28.894  1.00 26.92  ? 177  HIS D O     1 
ATOM   11303 C CB    . HIS D 1 177 ? -66.995  -84.253  27.844  1.00 31.75  ? 177  HIS D CB    1 
ATOM   11304 C CG    . HIS D 1 177 ? -68.366  -83.701  27.556  1.00 41.73  ? 177  HIS D CG    1 
ATOM   11305 N ND1   . HIS D 1 177 ? -69.165  -83.010  28.448  1.00 45.84  ? 177  HIS D ND1   1 
ATOM   11306 C CD2   . HIS D 1 177 ? -69.049  -83.712  26.402  1.00 40.99  ? 177  HIS D CD2   1 
ATOM   11307 C CE1   . HIS D 1 177 ? -70.267  -82.610  27.833  1.00 43.10  ? 177  HIS D CE1   1 
ATOM   11308 N NE2   . HIS D 1 177 ? -70.226  -83.049  26.604  1.00 41.06  ? 177  HIS D NE2   1 
ATOM   11309 N N     . LEU D 1 178 ? -63.477  -82.864  27.975  1.00 24.59  ? 178  LEU D N     1 
ATOM   11310 C CA    . LEU D 1 178 ? -62.137  -83.148  28.451  1.00 23.94  ? 178  LEU D CA    1 
ATOM   11311 C C     . LEU D 1 178 ? -62.072  -83.077  29.984  1.00 25.13  ? 178  LEU D C     1 
ATOM   11312 O O     . LEU D 1 178 ? -61.404  -83.920  30.586  1.00 27.49  ? 178  LEU D O     1 
ATOM   11313 C CB    . LEU D 1 178 ? -61.099  -82.267  27.758  1.00 20.32  ? 178  LEU D CB    1 
ATOM   11314 C CG    . LEU D 1 178 ? -61.029  -82.435  26.237  1.00 24.63  ? 178  LEU D CG    1 
ATOM   11315 C CD1   . LEU D 1 178 ? -60.096  -81.421  25.591  1.00 21.31  ? 178  LEU D CD1   1 
ATOM   11316 C CD2   . LEU D 1 178 ? -60.665  -83.870  25.850  1.00 22.14  ? 178  LEU D CD2   1 
ATOM   11317 N N     . PRO D 1 179 ? -62.736  -82.104  30.664  1.00 25.96  ? 179  PRO D N     1 
ATOM   11318 C CA    . PRO D 1 179 ? -62.718  -82.079  32.134  1.00 25.59  ? 179  PRO D CA    1 
ATOM   11319 C C     . PRO D 1 179 ? -63.101  -83.423  32.753  1.00 27.22  ? 179  PRO D C     1 
ATOM   11320 O O     . PRO D 1 179 ? -62.450  -83.880  33.701  1.00 24.35  ? 179  PRO D O     1 
ATOM   11321 C CB    . PRO D 1 179 ? -63.580  -80.859  32.536  1.00 23.54  ? 179  PRO D CB    1 
ATOM   11322 C CG    . PRO D 1 179 ? -63.537  -79.974  31.275  1.00 22.76  ? 179  PRO D CG    1 
ATOM   11323 C CD    . PRO D 1 179 ? -63.418  -80.930  30.071  1.00 23.12  ? 179  PRO D CD    1 
ATOM   11324 N N     . GLU D 1 180 ? -64.102  -84.089  32.156  1.00 25.04  ? 180  GLU D N     1 
ATOM   11325 C CA    . GLU D 1 180 ? -64.574  -85.363  32.685  1.00 28.80  ? 180  GLU D CA    1 
ATOM   11326 C C     . GLU D 1 180 ? -63.585  -86.490  32.371  1.00 29.21  ? 180  GLU D C     1 
ATOM   11327 O O     . GLU D 1 180 ? -63.314  -87.331  33.235  1.00 30.51  ? 180  GLU D O     1 
ATOM   11328 C CB    . GLU D 1 180 ? -66.021  -85.737  32.316  1.00 32.93  ? 180  GLU D CB    1 
ATOM   11329 C CG    . GLU D 1 180 ? -67.045  -84.635  32.615  1.00 37.19  ? 180  GLU D CG    1 
ATOM   11330 C CD    . GLU D 1 180 ? -67.334  -83.593  31.517  1.00 43.66  ? 180  GLU D CD    1 
ATOM   11331 O OE1   . GLU D 1 180 ? -68.501  -83.681  31.104  1.00 55.20  ? 180  GLU D OE1   1 
ATOM   11332 O OE2   . GLU D 1 180 ? -66.530  -82.743  31.037  1.00 39.49  ? 180  GLU D OE2   1 
ATOM   11333 N N     . LEU D 1 181 ? -63.065  -86.520  31.132  1.00 28.19  ? 181  LEU D N     1 
ATOM   11334 C CA    . LEU D 1 181 ? -62.115  -87.553  30.731  1.00 24.46  ? 181  LEU D CA    1 
ATOM   11335 C C     . LEU D 1 181 ? -60.837  -87.432  31.571  1.00 27.83  ? 181  LEU D C     1 
ATOM   11336 O O     . LEU D 1 181 ? -60.400  -88.400  32.199  1.00 26.02  ? 181  LEU D O     1 
ATOM   11337 C CB    . LEU D 1 181 ? -61.812  -87.478  29.238  1.00 21.13  ? 181  LEU D CB    1 
ATOM   11338 C CG    . LEU D 1 181 ? -60.785  -88.477  28.699  1.00 21.79  ? 181  LEU D CG    1 
ATOM   11339 C CD1   . LEU D 1 181 ? -61.285  -89.884  28.861  1.00 19.06  ? 181  LEU D CD1   1 
ATOM   11340 C CD2   . LEU D 1 181 ? -60.470  -88.232  27.229  1.00 18.22  ? 181  LEU D CD2   1 
ATOM   11341 N N     . TYR D 1 182 ? -60.253  -86.227  31.620  1.00 24.29  ? 182  TYR D N     1 
ATOM   11342 C CA    . TYR D 1 182 ? -58.965  -86.072  32.276  1.00 23.52  ? 182  TYR D CA    1 
ATOM   11343 C C     . TYR D 1 182 ? -59.121  -86.118  33.798  1.00 25.13  ? 182  TYR D C     1 
ATOM   11344 O O     . TYR D 1 182 ? -58.215  -86.588  34.502  1.00 23.88  ? 182  TYR D O     1 
ATOM   11345 C CB    . TYR D 1 182 ? -58.210  -84.841  31.792  1.00 19.58  ? 182  TYR D CB    1 
ATOM   11346 C CG    . TYR D 1 182 ? -57.928  -84.809  30.300  1.00 20.93  ? 182  TYR D CG    1 
ATOM   11347 C CD1   . TYR D 1 182 ? -57.833  -85.971  29.544  1.00 19.45  ? 182  TYR D CD1   1 
ATOM   11348 C CD2   . TYR D 1 182 ? -57.753  -83.588  29.645  1.00 21.96  ? 182  TYR D CD2   1 
ATOM   11349 C CE1   . TYR D 1 182 ? -57.560  -85.926  28.187  1.00 20.54  ? 182  TYR D CE1   1 
ATOM   11350 C CE2   . TYR D 1 182 ? -57.494  -83.541  28.288  1.00 19.86  ? 182  TYR D CE2   1 
ATOM   11351 C CZ    . TYR D 1 182 ? -57.387  -84.703  27.562  1.00 21.68  ? 182  TYR D CZ    1 
ATOM   11352 O OH    . TYR D 1 182 ? -57.081  -84.591  26.224  1.00 24.23  ? 182  TYR D OH    1 
ATOM   11353 N N     . GLY D 1 183 ? -60.295  -85.657  34.285  1.00 27.05  ? 183  GLY D N     1 
ATOM   11354 C CA    . GLY D 1 183 ? -60.640  -85.752  35.699  1.00 21.75  ? 183  GLY D CA    1 
ATOM   11355 C C     . GLY D 1 183 ? -60.655  -87.210  36.153  1.00 22.92  ? 183  GLY D C     1 
ATOM   11356 O O     . GLY D 1 183 ? -60.123  -87.552  37.202  1.00 25.44  ? 183  GLY D O     1 
ATOM   11357 N N     . MET D 1 184 ? -61.255  -88.079  35.335  1.00 25.37  ? 184  MET D N     1 
ATOM   11358 C CA    . MET D 1 184 ? -61.283  -89.502  35.623  1.00 23.18  ? 184  MET D CA    1 
ATOM   11359 C C     . MET D 1 184 ? -59.835  -90.023  35.671  1.00 25.79  ? 184  MET D C     1 
ATOM   11360 O O     . MET D 1 184 ? -59.466  -90.800  36.562  1.00 23.88  ? 184  MET D O     1 
ATOM   11361 C CB    . MET D 1 184 ? -62.235  -90.189  34.635  1.00 26.28  ? 184  MET D CB    1 
ATOM   11362 C CG    . MET D 1 184 ? -62.484  -91.682  34.800  1.00 30.51  ? 184  MET D CG    1 
ATOM   11363 S SD    . MET D 1 184 ? -61.149  -92.648  34.077  1.00 43.23  ? 184  MET D SD    1 
ATOM   11364 C CE    . MET D 1 184 ? -61.299  -92.280  32.315  1.00 41.50  ? 184  MET D CE    1 
ATOM   11365 N N     . ILE D 1 185 ? -58.974  -89.578  34.735  1.00 23.81  ? 185  ILE D N     1 
ATOM   11366 C CA    . ILE D 1 185 ? -57.595  -90.051  34.739  1.00 22.81  ? 185  ILE D CA    1 
ATOM   11367 C C     . ILE D 1 185 ? -56.901  -89.620  36.039  1.00 25.24  ? 185  ILE D C     1 
ATOM   11368 O O     . ILE D 1 185 ? -56.192  -90.418  36.665  1.00 23.78  ? 185  ILE D O     1 
ATOM   11369 C CB    . ILE D 1 185 ? -56.802  -89.627  33.487  1.00 22.83  ? 185  ILE D CB    1 
ATOM   11370 C CG1   . ILE D 1 185 ? -57.403  -90.232  32.213  1.00 24.55  ? 185  ILE D CG1   1 
ATOM   11371 C CG2   . ILE D 1 185 ? -55.304  -89.957  33.633  1.00 17.07  ? 185  ILE D CG2   1 
ATOM   11372 C CD1   . ILE D 1 185 ? -56.840  -89.645  30.933  1.00 24.85  ? 185  ILE D CD1   1 
ATOM   11373 N N     . ARG D 1 186 ? -57.079  -88.341  36.422  1.00 24.35  ? 186  ARG D N     1 
ATOM   11374 C CA    . ARG D 1 186 ? -56.463  -87.833  37.640  1.00 29.20  ? 186  ARG D CA    1 
ATOM   11375 C C     . ARG D 1 186 ? -56.942  -88.612  38.873  1.00 30.93  ? 186  ARG D C     1 
ATOM   11376 O O     . ARG D 1 186 ? -56.172  -88.837  39.817  1.00 33.01  ? 186  ARG D O     1 
ATOM   11377 C CB    . ARG D 1 186 ? -56.699  -86.338  37.859  1.00 27.33  ? 186  ARG D CB    1 
ATOM   11378 C CG    . ARG D 1 186 ? -55.893  -85.540  36.844  1.00 30.99  ? 186  ARG D CG    1 
ATOM   11379 C CD    . ARG D 1 186 ? -54.409  -85.489  37.167  1.00 29.57  ? 186  ARG D CD    1 
ATOM   11380 N NE    . ARG D 1 186 ? -53.786  -84.973  35.954  1.00 27.65  ? 186  ARG D NE    1 
ATOM   11381 C CZ    . ARG D 1 186 ? -52.705  -85.481  35.378  1.00 29.19  ? 186  ARG D CZ    1 
ATOM   11382 N NH1   . ARG D 1 186 ? -52.190  -84.862  34.332  1.00 24.71  ? 186  ARG D NH1   1 
ATOM   11383 N NH2   . ARG D 1 186 ? -52.160  -86.607  35.822  1.00 26.79  ? 186  ARG D NH2   1 
ATOM   11384 N N     . HIS D 1 187 ? -58.207  -89.046  38.849  1.00 27.18  ? 187  HIS D N     1 
ATOM   11385 C CA    . HIS D 1 187 ? -58.734  -89.820  39.954  1.00 29.17  ? 187  HIS D CA    1 
ATOM   11386 C C     . HIS D 1 187 ? -57.961  -91.127  40.112  1.00 31.58  ? 187  HIS D C     1 
ATOM   11387 O O     . HIS D 1 187 ? -57.513  -91.423  41.195  1.00 30.73  ? 187  HIS D O     1 
ATOM   11388 C CB    . HIS D 1 187 ? -60.264  -89.866  39.913  1.00 29.16  ? 187  HIS D CB    1 
ATOM   11389 C CG    . HIS D 1 187 ? -60.886  -90.737  40.943  1.00 39.84  ? 187  HIS D CG    1 
ATOM   11390 N ND1   . HIS D 1 187 ? -61.253  -90.322  42.201  1.00 41.77  ? 187  HIS D ND1   1 
ATOM   11391 C CD2   . HIS D 1 187 ? -61.204  -92.020  40.881  1.00 42.94  ? 187  HIS D CD2   1 
ATOM   11392 C CE1   . HIS D 1 187 ? -61.850  -91.317  42.849  1.00 39.60  ? 187  HIS D CE1   1 
ATOM   11393 N NE2   . HIS D 1 187 ? -61.826  -92.362  42.069  1.00 43.60  ? 187  HIS D NE2   1 
ATOM   11394 N N     . TYR D 1 188 ? -57.802  -91.942  39.056  1.00 31.61  ? 188  TYR D N     1 
ATOM   11395 C CA    . TYR D 1 188 ? -57.182  -93.244  39.249  1.00 25.05  ? 188  TYR D CA    1 
ATOM   11396 C C     . TYR D 1 188 ? -55.663  -93.205  39.068  1.00 25.18  ? 188  TYR D C     1 
ATOM   11397 O O     . TYR D 1 188 ? -54.976  -94.117  39.497  1.00 21.05  ? 188  TYR D O     1 
ATOM   11398 C CB    . TYR D 1 188 ? -57.753  -94.240  38.247  1.00 22.94  ? 188  TYR D CB    1 
ATOM   11399 C CG    . TYR D 1 188 ? -59.211  -94.523  38.546  1.00 28.37  ? 188  TYR D CG    1 
ATOM   11400 C CD1   . TYR D 1 188 ? -59.576  -95.362  39.618  1.00 25.20  ? 188  TYR D CD1   1 
ATOM   11401 C CD2   . TYR D 1 188 ? -60.223  -93.971  37.746  1.00 26.15  ? 188  TYR D CD2   1 
ATOM   11402 C CE1   . TYR D 1 188 ? -60.910  -95.604  39.904  1.00 26.70  ? 188  TYR D CE1   1 
ATOM   11403 C CE2   . TYR D 1 188 ? -61.561  -94.225  38.027  1.00 28.32  ? 188  TYR D CE2   1 
ATOM   11404 C CZ    . TYR D 1 188 ? -61.898  -95.015  39.126  1.00 28.40  ? 188  TYR D CZ    1 
ATOM   11405 O OH    . TYR D 1 188 ? -63.170  -95.373  39.450  1.00 25.65  ? 188  TYR D OH    1 
ATOM   11406 N N     . GLN D 1 189 ? -55.151  -92.218  38.330  1.00 25.44  ? 189  GLN D N     1 
ATOM   11407 C CA    . GLN D 1 189 ? -53.751  -92.192  37.914  1.00 22.29  ? 189  GLN D CA    1 
ATOM   11408 C C     . GLN D 1 189 ? -53.214  -90.781  38.140  1.00 23.07  ? 189  GLN D C     1 
ATOM   11409 O O     . GLN D 1 189 ? -52.857  -90.109  37.179  1.00 22.74  ? 189  GLN D O     1 
ATOM   11410 C CB    . GLN D 1 189 ? -53.669  -92.569  36.428  1.00 21.59  ? 189  GLN D CB    1 
ATOM   11411 C CG    . GLN D 1 189 ? -54.110  -94.002  36.109  1.00 22.36  ? 189  GLN D CG    1 
ATOM   11412 C CD    . GLN D 1 189 ? -53.031  -94.997  36.486  1.00 23.97  ? 189  GLN D CD    1 
ATOM   11413 O OE1   . GLN D 1 189 ? -51.843  -94.646  36.593  1.00 24.98  ? 189  GLN D OE1   1 
ATOM   11414 N NE2   . GLN D 1 189 ? -53.428  -96.246  36.693  1.00 24.52  ? 189  GLN D NE2   1 
ATOM   11415 N N     . PRO D 1 190 ? -53.135  -90.288  39.402  1.00 24.47  ? 190  PRO D N     1 
ATOM   11416 C CA    . PRO D 1 190 ? -52.780  -88.887  39.650  1.00 25.62  ? 190  PRO D CA    1 
ATOM   11417 C C     . PRO D 1 190 ? -51.444  -88.470  39.026  1.00 27.05  ? 190  PRO D C     1 
ATOM   11418 O O     . PRO D 1 190 ? -51.250  -87.317  38.630  1.00 28.77  ? 190  PRO D O     1 
ATOM   11419 C CB    . PRO D 1 190 ? -52.811  -88.719  41.185  1.00 22.97  ? 190  PRO D CB    1 
ATOM   11420 C CG    . PRO D 1 190 ? -52.655  -90.174  41.700  1.00 21.93  ? 190  PRO D CG    1 
ATOM   11421 C CD    . PRO D 1 190 ? -53.283  -91.082  40.646  1.00 22.70  ? 190  PRO D CD    1 
ATOM   11422 N N     . ASN D 1 191 ? -50.541  -89.438  38.884  1.00 25.95  ? 191  ASN D N     1 
ATOM   11423 C CA    . ASN D 1 191 ? -49.170  -89.187  38.472  1.00 26.28  ? 191  ASN D CA    1 
ATOM   11424 C C     . ASN D 1 191 ? -48.926  -89.406  36.966  1.00 25.98  ? 191  ASN D C     1 
ATOM   11425 O O     . ASN D 1 191 ? -47.813  -89.243  36.490  1.00 21.50  ? 191  ASN D O     1 
ATOM   11426 C CB    . ASN D 1 191 ? -48.226  -90.037  39.312  1.00 32.94  ? 191  ASN D CB    1 
ATOM   11427 C CG    . ASN D 1 191 ? -46.877  -89.375  39.331  1.00 48.61  ? 191  ASN D CG    1 
ATOM   11428 O OD1   . ASN D 1 191 ? -46.788  -88.188  39.685  1.00 45.61  ? 191  ASN D OD1   1 
ATOM   11429 N ND2   . ASN D 1 191 ? -45.855  -90.082  38.852  1.00 43.86  ? 191  ASN D ND2   1 
ATOM   11430 N N     . ALA D 1 192 ? -49.956  -89.802  36.200  1.00 24.13  ? 192  ALA D N     1 
ATOM   11431 C CA    . ALA D 1 192 ? -49.781  -90.123  34.798  1.00 23.34  ? 192  ALA D CA    1 
ATOM   11432 C C     . ALA D 1 192 ? -49.559  -88.830  34.005  1.00 23.89  ? 192  ALA D C     1 
ATOM   11433 O O     . ALA D 1 192 ? -50.139  -87.787  34.310  1.00 23.52  ? 192  ALA D O     1 
ATOM   11434 C CB    . ALA D 1 192 ? -51.000  -90.850  34.292  1.00 22.70  ? 192  ALA D CB    1 
ATOM   11435 N N     . ILE D 1 193 ? -48.679  -88.899  33.001  1.00 21.84  ? 193  ILE D N     1 
ATOM   11436 C CA    . ILE D 1 193 ? -48.506  -87.775  32.093  1.00 23.76  ? 193  ILE D CA    1 
ATOM   11437 C C     . ILE D 1 193 ? -49.618  -87.833  31.042  1.00 23.46  ? 193  ILE D C     1 
ATOM   11438 O O     . ILE D 1 193 ? -49.816  -88.882  30.426  1.00 24.55  ? 193  ILE D O     1 
ATOM   11439 C CB    . ILE D 1 193 ? -47.109  -87.841  31.443  1.00 23.45  ? 193  ILE D CB    1 
ATOM   11440 C CG1   . ILE D 1 193 ? -46.007  -87.508  32.440  1.00 23.83  ? 193  ILE D CG1   1 
ATOM   11441 C CG2   . ILE D 1 193 ? -47.053  -86.971  30.182  1.00 19.20  ? 193  ILE D CG2   1 
ATOM   11442 C CD1   . ILE D 1 193 ? -45.957  -86.033  32.818  1.00 23.98  ? 193  ILE D CD1   1 
ATOM   11443 N N     . ILE D 1 194 ? -50.345  -86.723  30.854  1.00 19.83  ? 194  ILE D N     1 
ATOM   11444 C CA    . ILE D 1 194 ? -51.328  -86.679  29.777  1.00 19.93  ? 194  ILE D CA    1 
ATOM   11445 C C     . ILE D 1 194 ? -50.774  -85.865  28.605  1.00 21.92  ? 194  ILE D C     1 
ATOM   11446 O O     . ILE D 1 194 ? -50.525  -84.654  28.729  1.00 21.00  ? 194  ILE D O     1 
ATOM   11447 C CB    . ILE D 1 194 ? -52.668  -86.099  30.258  1.00 20.26  ? 194  ILE D CB    1 
ATOM   11448 C CG1   . ILE D 1 194 ? -53.304  -86.940  31.402  1.00 18.16  ? 194  ILE D CG1   1 
ATOM   11449 C CG2   . ILE D 1 194 ? -53.629  -85.949  29.070  1.00 19.08  ? 194  ILE D CG2   1 
ATOM   11450 C CD1   . ILE D 1 194 ? -54.577  -86.303  31.934  1.00 15.76  ? 194  ILE D CD1   1 
ATOM   11451 N N     . VAL D 1 195 ? -50.604  -86.544  27.467  1.00 20.69  ? 195  VAL D N     1 
ATOM   11452 C CA    . VAL D 1 195 ? -50.110  -85.931  26.246  1.00 21.79  ? 195  VAL D CA    1 
ATOM   11453 C C     . VAL D 1 195 ? -51.276  -85.787  25.277  1.00 22.01  ? 195  VAL D C     1 
ATOM   11454 O O     . VAL D 1 195 ? -52.038  -86.728  25.079  1.00 24.67  ? 195  VAL D O     1 
ATOM   11455 C CB    . VAL D 1 195 ? -48.998  -86.766  25.583  1.00 22.34  ? 195  VAL D CB    1 
ATOM   11456 C CG1   . VAL D 1 195 ? -48.429  -86.052  24.340  1.00 18.41  ? 195  VAL D CG1   1 
ATOM   11457 C CG2   . VAL D 1 195 ? -47.897  -87.155  26.573  1.00 19.10  ? 195  VAL D CG2   1 
ATOM   11458 N N     . SER D 1 196 ? -51.299  -84.692  24.562  1.00 22.49  ? 196  SER D N     1 
ATOM   11459 C CA    . SER D 1 196 ? -52.293  -84.458  23.559  1.00 25.56  ? 196  SER D CA    1 
ATOM   11460 C C     . SER D 1 196 ? -51.745  -83.989  22.223  1.00 27.69  ? 196  SER D C     1 
ATOM   11461 O O     . SER D 1 196 ? -50.987  -83.097  22.159  1.00 25.63  ? 196  SER D O     1 
ATOM   11462 C CB    . SER D 1 196 ? -53.294  -83.448  24.054  1.00 31.30  ? 196  SER D CB    1 
ATOM   11463 O OG    . SER D 1 196 ? -54.349  -83.327  23.176  1.00 33.14  ? 196  SER D OG    1 
ATOM   11464 N N     . ASN D 1 197 ? -52.165  -84.662  21.171  1.00 27.43  ? 197  ASN D N     1 
ATOM   11465 C CA    . ASN D 1 197 ? -51.872  -84.380  19.784  1.00 35.79  ? 197  ASN D CA    1 
ATOM   11466 C C     . ASN D 1 197 ? -52.608  -83.164  19.260  1.00 44.60  ? 197  ASN D C     1 
ATOM   11467 O O     . ASN D 1 197 ? -52.253  -82.564  18.286  1.00 54.09  ? 197  ASN D O     1 
ATOM   11468 C CB    . ASN D 1 197 ? -52.226  -85.563  18.942  1.00 35.58  ? 197  ASN D CB    1 
ATOM   11469 C CG    . ASN D 1 197 ? -51.256  -85.787  17.844  1.00 43.77  ? 197  ASN D CG    1 
ATOM   11470 O OD1   . ASN D 1 197 ? -50.220  -85.174  17.808  1.00 40.70  ? 197  ASN D OD1   1 
ATOM   11471 N ND2   . ASN D 1 197 ? -51.589  -86.658  16.938  1.00 38.21  ? 197  ASN D ND2   1 
ATOM   11472 N N     . THR D 1 198 ? -53.684  -82.822  19.902  1.00 68.17  ? 198  THR D N     1 
ATOM   11473 C CA    . THR D 1 198 ? -54.438  -81.681  19.512  1.00 80.51  ? 198  THR D CA    1 
ATOM   11474 C C     . THR D 1 198 ? -54.550  -80.729  20.681  1.00 68.45  ? 198  THR D C     1 
ATOM   11475 O O     . THR D 1 198 ? -53.562  -80.443  21.341  1.00 63.35  ? 198  THR D O     1 
ATOM   11476 C CB    . THR D 1 198 ? -55.827  -82.102  19.053  1.00 85.26  ? 198  THR D CB    1 
ATOM   11477 O OG1   . THR D 1 198 ? -56.348  -81.083  18.214  1.00 100.15 ? 198  THR D OG1   1 
ATOM   11478 C CG2   . THR D 1 198 ? -56.706  -82.290  20.218  1.00 66.01  ? 198  THR D CG2   1 
ATOM   11479 N N     . GLN D 1 205 ? -52.894  -71.364  23.405  1.00 71.48  ? 205  GLN D N     1 
ATOM   11480 C CA    . GLN D 1 205 ? -53.752  -71.693  24.577  1.00 89.61  ? 205  GLN D CA    1 
ATOM   11481 C C     . GLN D 1 205 ? -54.155  -73.175  24.546  1.00 78.29  ? 205  GLN D C     1 
ATOM   11482 O O     . GLN D 1 205 ? -54.653  -73.652  23.531  1.00 67.64  ? 205  GLN D O     1 
ATOM   11483 C CB    . GLN D 1 205 ? -55.002  -70.808  24.690  1.00 99.26  ? 205  GLN D CB    1 
ATOM   11484 C CG    . GLN D 1 205 ? -55.597  -70.804  26.096  1.00 115.65 ? 205  GLN D CG    1 
ATOM   11485 C CD    . GLN D 1 205 ? -57.100  -70.995  26.154  1.00 122.60 ? 205  GLN D CD    1 
ATOM   11486 O OE1   . GLN D 1 205 ? -57.769  -71.188  25.132  1.00 131.46 ? 205  GLN D OE1   1 
ATOM   11487 N NE2   . GLN D 1 205 ? -57.641  -70.954  27.361  1.00 104.80 ? 205  GLN D NE2   1 
ATOM   11488 N N     . VAL D 1 206 ? -53.937  -73.873  25.672  1.00 73.39  ? 206  VAL D N     1 
ATOM   11489 C CA    . VAL D 1 206 ? -54.022  -75.325  25.786  1.00 65.30  ? 206  VAL D CA    1 
ATOM   11490 C C     . VAL D 1 206 ? -55.482  -75.760  25.964  1.00 56.53  ? 206  VAL D C     1 
ATOM   11491 O O     . VAL D 1 206 ? -56.309  -75.027  26.500  1.00 53.67  ? 206  VAL D O     1 
ATOM   11492 C CB    . VAL D 1 206 ? -53.135  -75.813  26.955  1.00 63.61  ? 206  VAL D CB    1 
ATOM   11493 C CG1   . VAL D 1 206 ? -53.631  -75.357  28.339  1.00 62.37  ? 206  VAL D CG1   1 
ATOM   11494 C CG2   . VAL D 1 206 ? -52.933  -77.318  26.901  1.00 58.84  ? 206  VAL D CG2   1 
ATOM   11495 N N     . SER D 1 207 ? -55.796  -76.981  25.536  1.00 51.28  ? 207  SER D N     1 
ATOM   11496 C CA    . SER D 1 207 ? -57.197  -77.344  25.381  1.00 51.07  ? 207  SER D CA    1 
ATOM   11497 C C     . SER D 1 207 ? -57.846  -77.774  26.705  1.00 46.76  ? 207  SER D C     1 
ATOM   11498 O O     . SER D 1 207 ? -59.073  -77.892  26.773  1.00 46.78  ? 207  SER D O     1 
ATOM   11499 C CB    . SER D 1 207 ? -57.401  -78.361  24.275  1.00 51.94  ? 207  SER D CB    1 
ATOM   11500 O OG    . SER D 1 207 ? -56.867  -79.607  24.686  1.00 59.33  ? 207  SER D OG    1 
ATOM   11501 N N     . ASP D 1 208 ? -57.042  -78.007  27.753  1.00 34.88  ? 208  ASP D N     1 
ATOM   11502 C CA    . ASP D 1 208 ? -57.580  -78.383  29.054  1.00 32.42  ? 208  ASP D CA    1 
ATOM   11503 C C     . ASP D 1 208 ? -56.488  -78.260  30.104  1.00 30.48  ? 208  ASP D C     1 
ATOM   11504 O O     . ASP D 1 208 ? -55.365  -78.687  29.862  1.00 31.96  ? 208  ASP D O     1 
ATOM   11505 C CB    . ASP D 1 208 ? -58.126  -79.803  29.109  1.00 27.37  ? 208  ASP D CB    1 
ATOM   11506 C CG    . ASP D 1 208 ? -58.929  -80.095  30.376  1.00 31.59  ? 208  ASP D CG    1 
ATOM   11507 O OD1   . ASP D 1 208 ? -60.153  -79.809  30.363  1.00 34.74  ? 208  ASP D OD1   1 
ATOM   11508 O OD2   . ASP D 1 208 ? -58.330  -80.510  31.412  1.00 28.56  ? 208  ASP D OD2   1 
ATOM   11509 N N     . PRO D 1 209 ? -56.784  -77.713  31.306  1.00 32.77  ? 209  PRO D N     1 
ATOM   11510 C CA    . PRO D 1 209 ? -55.773  -77.558  32.353  1.00 30.90  ? 209  PRO D CA    1 
ATOM   11511 C C     . PRO D 1 209 ? -55.043  -78.856  32.715  1.00 31.03  ? 209  PRO D C     1 
ATOM   11512 O O     . PRO D 1 209 ? -53.921  -78.801  33.200  1.00 29.43  ? 209  PRO D O     1 
ATOM   11513 C CB    . PRO D 1 209 ? -56.575  -76.991  33.556  1.00 28.13  ? 209  PRO D CB    1 
ATOM   11514 C CG    . PRO D 1 209 ? -57.732  -76.289  32.870  1.00 27.89  ? 209  PRO D CG    1 
ATOM   11515 C CD    . PRO D 1 209 ? -58.099  -77.171  31.708  1.00 29.66  ? 209  PRO D CD    1 
ATOM   11516 N N     . GLU D 1 210 ? -55.670  -80.022  32.489  1.00 27.34  ? 210  GLU D N     1 
ATOM   11517 C CA    . GLU D 1 210 ? -55.075  -81.273  32.935  1.00 27.06  ? 210  GLU D CA    1 
ATOM   11518 C C     . GLU D 1 210 ? -54.012  -81.803  31.961  1.00 29.89  ? 210  GLU D C     1 
ATOM   11519 O O     . GLU D 1 210 ? -53.265  -82.719  32.319  1.00 30.38  ? 210  GLU D O     1 
ATOM   11520 C CB    . GLU D 1 210 ? -56.113  -82.347  33.242  1.00 25.97  ? 210  GLU D CB    1 
ATOM   11521 C CG    . GLU D 1 210 ? -56.852  -82.099  34.545  1.00 26.77  ? 210  GLU D CG    1 
ATOM   11522 C CD    . GLU D 1 210 ? -55.942  -82.017  35.772  1.00 34.02  ? 210  GLU D CD    1 
ATOM   11523 O OE1   . GLU D 1 210 ? -54.768  -82.473  35.793  1.00 30.42  ? 210  GLU D OE1   1 
ATOM   11524 O OE2   . GLU D 1 210 ? -56.433  -81.442  36.767  1.00 36.48  ? 210  GLU D OE2   1 
ATOM   11525 N N     . ILE D 1 211 ? -53.940  -81.246  30.732  1.00 25.95  ? 211  ILE D N     1 
ATOM   11526 C CA    . ILE D 1 211 ? -52.902  -81.638  29.789  1.00 23.48  ? 211  ILE D CA    1 
ATOM   11527 C C     . ILE D 1 211 ? -51.520  -81.265  30.339  1.00 22.48  ? 211  ILE D C     1 
ATOM   11528 O O     . ILE D 1 211 ? -51.326  -80.173  30.844  1.00 24.47  ? 211  ILE D O     1 
ATOM   11529 C CB    . ILE D 1 211 ? -53.177  -81.005  28.421  1.00 24.98  ? 211  ILE D CB    1 
ATOM   11530 C CG1   . ILE D 1 211 ? -54.239  -81.784  27.671  1.00 23.94  ? 211  ILE D CG1   1 
ATOM   11531 C CG2   . ILE D 1 211 ? -51.888  -80.939  27.600  1.00 20.54  ? 211  ILE D CG2   1 
ATOM   11532 C CD1   . ILE D 1 211 ? -54.954  -80.938  26.638  1.00 32.11  ? 211  ILE D CD1   1 
ATOM   11533 N N     . ASP D 1 212 ? -50.551  -82.179  30.215  1.00 20.99  ? 212  ASP D N     1 
ATOM   11534 C CA    . ASP D 1 212 ? -49.194  -81.995  30.709  1.00 20.22  ? 212  ASP D CA    1 
ATOM   11535 C C     . ASP D 1 212 ? -48.192  -81.718  29.580  1.00 20.07  ? 212  ASP D C     1 
ATOM   11536 O O     . ASP D 1 212 ? -47.160  -81.086  29.798  1.00 21.22  ? 212  ASP D O     1 
ATOM   11537 C CB    . ASP D 1 212 ? -48.759  -83.232  31.475  1.00 21.03  ? 212  ASP D CB    1 
ATOM   11538 C CG    . ASP D 1 212 ? -49.597  -83.547  32.705  1.00 20.77  ? 212  ASP D CG    1 
ATOM   11539 O OD1   . ASP D 1 212 ? -49.983  -82.589  33.400  1.00 23.29  ? 212  ASP D OD1   1 
ATOM   11540 O OD2   . ASP D 1 212 ? -49.777  -84.752  33.001  1.00 22.47  ? 212  ASP D OD2   1 
ATOM   11541 N N     . VAL D 1 213 ? -48.420  -82.303  28.426  1.00 20.07  ? 213  VAL D N     1 
ATOM   11542 C CA    . VAL D 1 213 ? -47.562  -82.229  27.266  1.00 19.53  ? 213  VAL D CA    1 
ATOM   11543 C C     . VAL D 1 213 ? -48.365  -82.018  25.992  1.00 20.82  ? 213  VAL D C     1 
ATOM   11544 O O     . VAL D 1 213 ? -49.369  -82.583  25.824  1.00 21.82  ? 213  VAL D O     1 
ATOM   11545 C CB    . VAL D 1 213 ? -46.734  -83.532  27.102  1.00 17.95  ? 213  VAL D CB    1 
ATOM   11546 C CG1   . VAL D 1 213 ? -45.696  -83.423  26.008  1.00 16.35  ? 213  VAL D CG1   1 
ATOM   11547 C CG2   . VAL D 1 213 ? -46.080  -83.946  28.387  1.00 16.73  ? 213  VAL D CG2   1 
ATOM   11548 N N     . VAL D 1 214 ? -47.855  -81.204  25.104  1.00 18.81  ? 214  VAL D N     1 
ATOM   11549 C CA    . VAL D 1 214 ? -48.424  -80.901  23.839  1.00 24.43  ? 214  VAL D CA    1 
ATOM   11550 C C     . VAL D 1 214 ? -47.425  -81.300  22.737  1.00 25.12  ? 214  VAL D C     1 
ATOM   11551 O O     . VAL D 1 214 ? -46.264  -81.253  22.938  1.00 22.98  ? 214  VAL D O     1 
ATOM   11552 C CB    . VAL D 1 214 ? -48.786  -79.407  23.816  1.00 27.29  ? 214  VAL D CB    1 
ATOM   11553 C CG1   . VAL D 1 214 ? -48.967  -78.873  22.451  1.00 31.98  ? 214  VAL D CG1   1 
ATOM   11554 C CG2   . VAL D 1 214 ? -50.033  -79.161  24.595  1.00 28.25  ? 214  VAL D CG2   1 
ATOM   11555 N N     . THR D 1 215 ? -47.903  -81.807  21.623  1.00 23.47  ? 215  THR D N     1 
ATOM   11556 C CA    . THR D 1 215 ? -47.067  -82.126  20.478  1.00 26.93  ? 215  THR D CA    1 
ATOM   11557 C C     . THR D 1 215 ? -46.763  -80.958  19.515  1.00 31.47  ? 215  THR D C     1 
ATOM   11558 O O     . THR D 1 215 ? -47.488  -80.016  19.426  1.00 35.16  ? 215  THR D O     1 
ATOM   11559 C CB    . THR D 1 215 ? -47.618  -83.284  19.673  1.00 24.50  ? 215  THR D CB    1 
ATOM   11560 O OG1   . THR D 1 215 ? -48.830  -82.898  19.085  1.00 25.16  ? 215  THR D OG1   1 
ATOM   11561 C CG2   . THR D 1 215 ? -47.867  -84.438  20.538  1.00 23.57  ? 215  THR D CG2   1 
ATOM   11562 N N     . TYR D 1 216 ? -45.650  -81.036  18.822  1.00 27.67  ? 216  TYR D N     1 
ATOM   11563 C CA    . TYR D 1 216 ? -45.217  -80.043  17.873  1.00 29.92  ? 216  TYR D CA    1 
ATOM   11564 C C     . TYR D 1 216 ? -44.645  -80.705  16.632  1.00 31.88  ? 216  TYR D C     1 
ATOM   11565 O O     . TYR D 1 216 ? -44.257  -81.825  16.689  1.00 31.34  ? 216  TYR D O     1 
ATOM   11566 C CB    . TYR D 1 216 ? -44.148  -79.158  18.504  1.00 32.85  ? 216  TYR D CB    1 
ATOM   11567 C CG    . TYR D 1 216 ? -44.610  -78.323  19.652  1.00 39.76  ? 216  TYR D CG    1 
ATOM   11568 C CD1   . TYR D 1 216 ? -44.587  -78.796  20.936  1.00 39.38  ? 216  TYR D CD1   1 
ATOM   11569 C CD2   . TYR D 1 216 ? -45.055  -77.060  19.450  1.00 43.16  ? 216  TYR D CD2   1 
ATOM   11570 C CE1   . TYR D 1 216 ? -45.027  -78.038  21.976  1.00 46.89  ? 216  TYR D CE1   1 
ATOM   11571 C CE2   . TYR D 1 216 ? -45.481  -76.282  20.488  1.00 50.71  ? 216  TYR D CE2   1 
ATOM   11572 C CZ    . TYR D 1 216 ? -45.470  -76.777  21.744  1.00 46.47  ? 216  TYR D CZ    1 
ATOM   11573 O OH    . TYR D 1 216 ? -45.885  -75.986  22.737  1.00 44.07  ? 216  TYR D OH    1 
ATOM   11574 N N     . GLU D 1 217 ? -44.644  -80.011  15.508  1.00 34.29  ? 217  GLU D N     1 
ATOM   11575 C CA    . GLU D 1 217 ? -44.034  -80.491  14.265  1.00 41.79  ? 217  GLU D CA    1 
ATOM   11576 C C     . GLU D 1 217 ? -42.511  -80.569  14.433  1.00 37.49  ? 217  GLU D C     1 
ATOM   11577 O O     . GLU D 1 217 ? -41.895  -79.729  15.098  1.00 38.59  ? 217  GLU D O     1 
ATOM   11578 C CB    . GLU D 1 217 ? -44.566  -79.886  12.963  1.00 52.72  ? 217  GLU D CB    1 
ATOM   11579 C CG    . GLU D 1 217 ? -44.148  -78.433  12.764  1.00 81.76  ? 217  GLU D CG    1 
ATOM   11580 C CD    . GLU D 1 217 ? -44.066  -77.963  11.315  1.00 106.10 ? 217  GLU D CD    1 
ATOM   11581 O OE1   . GLU D 1 217 ? -42.939  -77.742  10.786  1.00 110.25 ? 217  GLU D OE1   1 
ATOM   11582 O OE2   . GLU D 1 217 ? -45.149  -77.781  10.710  1.00 90.69  ? 217  GLU D OE2   1 
ATOM   11583 N N     . ARG D 1 218 ? -41.911  -81.600  13.831  1.00 35.42  ? 218  ARG D N     1 
ATOM   11584 C CA    . ARG D 1 218 ? -40.520  -81.915  14.126  1.00 36.58  ? 218  ARG D CA    1 
ATOM   11585 C C     . ARG D 1 218 ? -39.606  -80.787  13.660  1.00 38.24  ? 218  ARG D C     1 
ATOM   11586 O O     . ARG D 1 218 ? -38.513  -80.614  14.202  1.00 45.66  ? 218  ARG D O     1 
ATOM   11587 C CB    . ARG D 1 218 ? -40.089  -83.325  13.710  1.00 34.39  ? 218  ARG D CB    1 
ATOM   11588 C CG    . ARG D 1 218 ? -39.970  -83.531  12.215  1.00 34.03  ? 218  ARG D CG    1 
ATOM   11589 C CD    . ARG D 1 218 ? -39.924  -85.012  11.925  1.00 36.55  ? 218  ARG D CD    1 
ATOM   11590 N NE    . ARG D 1 218 ? -40.257  -85.146  10.498  1.00 42.78  ? 218  ARG D NE    1 
ATOM   11591 C CZ    . ARG D 1 218 ? -39.316  -85.072  9.562   1.00 47.39  ? 218  ARG D CZ    1 
ATOM   11592 N NH1   . ARG D 1 218 ? -38.034  -84.932  9.922   1.00 42.43  ? 218  ARG D NH1   1 
ATOM   11593 N NH2   . ARG D 1 218 ? -39.664  -85.181  8.293   1.00 58.21  ? 218  ARG D NH2   1 
ATOM   11594 N N     . ARG D 1 219 ? -40.092  -79.976  12.721  1.00 39.79  ? 219  ARG D N     1 
ATOM   11595 C CA    . ARG D 1 219 ? -39.266  -78.921  12.145  1.00 46.13  ? 219  ARG D CA    1 
ATOM   11596 C C     . ARG D 1 219 ? -39.391  -77.607  12.923  1.00 44.80  ? 219  ARG D C     1 
ATOM   11597 O O     . ARG D 1 219 ? -38.725  -76.652  12.530  1.00 45.58  ? 219  ARG D O     1 
ATOM   11598 C CB    . ARG D 1 219 ? -39.431  -78.763  10.623  1.00 49.39  ? 219  ARG D CB    1 
ATOM   11599 C CG    . ARG D 1 219 ? -38.677  -79.897  9.915   1.00 66.03  ? 219  ARG D CG    1 
ATOM   11600 C CD    . ARG D 1 219 ? -38.698  -79.897  8.415   1.00 75.32  ? 219  ARG D CD    1 
ATOM   11601 N NE    . ARG D 1 219 ? -39.701  -80.847  7.906   1.00 86.57  ? 219  ARG D NE    1 
ATOM   11602 C CZ    . ARG D 1 219 ? -39.515  -81.787  6.981   1.00 81.60  ? 219  ARG D CZ    1 
ATOM   11603 N NH1   . ARG D 1 219 ? -38.313  -81.976  6.454   1.00 76.84  ? 219  ARG D NH1   1 
ATOM   11604 N NH2   . ARG D 1 219 ? -40.549  -82.494  6.557   1.00 75.72  ? 219  ARG D NH2   1 
ATOM   11605 N N     . THR D 1 220 ? -40.201  -77.556  14.004  1.00 36.28  ? 220  THR D N     1 
ATOM   11606 C CA    . THR D 1 220 ? -40.364  -76.315  14.756  1.00 39.85  ? 220  THR D CA    1 
ATOM   11607 C C     . THR D 1 220 ? -38.985  -75.664  14.963  1.00 45.76  ? 220  THR D C     1 
ATOM   11608 O O     . THR D 1 220 ? -38.098  -76.296  15.542  1.00 41.31  ? 220  THR D O     1 
ATOM   11609 C CB    . THR D 1 220 ? -41.044  -76.551  16.115  1.00 41.38  ? 220  THR D CB    1 
ATOM   11610 O OG1   . THR D 1 220 ? -42.268  -77.226  15.852  1.00 37.91  ? 220  THR D OG1   1 
ATOM   11611 C CG2   . THR D 1 220 ? -41.285  -75.257  16.890  1.00 44.90  ? 220  THR D CG2   1 
ATOM   11612 N N     . PRO D 1 221 ? -38.745  -74.407  14.518  1.00 47.37  ? 221  PRO D N     1 
ATOM   11613 C CA    . PRO D 1 221 ? -37.403  -73.818  14.577  1.00 50.42  ? 221  PRO D CA    1 
ATOM   11614 C C     . PRO D 1 221 ? -36.937  -73.383  15.971  1.00 51.88  ? 221  PRO D C     1 
ATOM   11615 O O     . PRO D 1 221 ? -35.745  -73.518  16.286  1.00 46.62  ? 221  PRO D O     1 
ATOM   11616 C CB    . PRO D 1 221 ? -37.429  -72.691  13.521  1.00 51.48  ? 221  PRO D CB    1 
ATOM   11617 C CG    . PRO D 1 221 ? -38.919  -72.340  13.388  1.00 50.67  ? 221  PRO D CG    1 
ATOM   11618 C CD    . PRO D 1 221 ? -39.742  -73.515  13.901  1.00 46.64  ? 221  PRO D CD    1 
ATOM   11619 N N     . ASP D 1 222 ? -37.872  -72.891  16.807  1.00 51.14  ? 222  ASP D N     1 
ATOM   11620 C CA    . ASP D 1 222 ? -37.483  -72.218  18.046  1.00 57.59  ? 222  ASP D CA    1 
ATOM   11621 C C     . ASP D 1 222 ? -38.003  -72.981  19.256  1.00 47.34  ? 222  ASP D C     1 
ATOM   11622 O O     . ASP D 1 222 ? -38.940  -73.764  19.129  1.00 47.22  ? 222  ASP D O     1 
ATOM   11623 C CB    . ASP D 1 222 ? -38.051  -70.808  18.166  1.00 68.36  ? 222  ASP D CB    1 
ATOM   11624 C CG    . ASP D 1 222 ? -37.802  -69.890  16.981  1.00 86.22  ? 222  ASP D CG    1 
ATOM   11625 O OD1   . ASP D 1 222 ? -36.598  -69.612  16.710  1.00 70.06  ? 222  ASP D OD1   1 
ATOM   11626 O OD2   . ASP D 1 222 ? -38.821  -69.483  16.344  1.00 81.29  ? 222  ASP D OD2   1 
ATOM   11627 N N     . GLU D 1 223 ? -37.410  -72.676  20.417  1.00 39.77  ? 223  GLU D N     1 
ATOM   11628 C CA    . GLU D 1 223 ? -37.829  -73.176  21.715  1.00 46.69  ? 223  GLU D CA    1 
ATOM   11629 C C     . GLU D 1 223 ? -39.356  -73.135  21.840  1.00 48.40  ? 223  GLU D C     1 
ATOM   11630 O O     . GLU D 1 223 ? -39.989  -72.146  21.483  1.00 52.23  ? 223  GLU D O     1 
ATOM   11631 C CB    . GLU D 1 223 ? -37.081  -72.408  22.804  1.00 46.03  ? 223  GLU D CB    1 
ATOM   11632 C CG    . GLU D 1 223 ? -37.408  -72.975  24.183  1.00 69.68  ? 223  GLU D CG    1 
ATOM   11633 C CD    . GLU D 1 223 ? -36.683  -72.467  25.404  1.00 78.81  ? 223  GLU D CD    1 
ATOM   11634 O OE1   . GLU D 1 223 ? -36.829  -73.127  26.463  1.00 67.17  ? 223  GLU D OE1   1 
ATOM   11635 O OE2   . GLU D 1 223 ? -35.949  -71.462  25.299  1.00 87.81  ? 223  GLU D OE2   1 
ATOM   11636 N N     . ILE D 1 224 ? -39.955  -74.231  22.340  1.00 45.37  ? 224  ILE D N     1 
ATOM   11637 C CA    . ILE D 1 224 ? -41.405  -74.408  22.292  1.00 44.97  ? 224  ILE D CA    1 
ATOM   11638 C C     . ILE D 1 224 ? -42.051  -73.554  23.387  1.00 53.28  ? 224  ILE D C     1 
ATOM   11639 O O     . ILE D 1 224 ? -41.361  -73.046  24.302  1.00 44.52  ? 224  ILE D O     1 
ATOM   11640 C CB    . ILE D 1 224 ? -41.771  -75.895  22.456  1.00 41.59  ? 224  ILE D CB    1 
ATOM   11641 C CG1   . ILE D 1 224 ? -41.238  -76.413  23.752  1.00 36.97  ? 224  ILE D CG1   1 
ATOM   11642 C CG2   . ILE D 1 224 ? -41.283  -76.759  21.285  1.00 37.96  ? 224  ILE D CG2   1 
ATOM   11643 C CD1   . ILE D 1 224 ? -42.127  -77.430  24.406  1.00 52.13  ? 224  ILE D CD1   1 
ATOM   11644 N N     . TYR D 1 225 ? -43.394  -73.452  23.306  1.00 60.18  ? 225  TYR D N     1 
ATOM   11645 C CA    . TYR D 1 225 ? -44.212  -72.678  24.233  1.00 65.62  ? 225  TYR D CA    1 
ATOM   11646 C C     . TYR D 1 225 ? -44.549  -73.484  25.496  1.00 53.43  ? 225  TYR D C     1 
ATOM   11647 O O     . TYR D 1 225 ? -45.029  -74.618  25.410  1.00 53.01  ? 225  TYR D O     1 
ATOM   11648 C CB    . TYR D 1 225 ? -45.476  -72.364  23.418  1.00 81.50  ? 225  TYR D CB    1 
ATOM   11649 C CG    . TYR D 1 225 ? -46.604  -71.711  24.214  1.00 99.06  ? 225  TYR D CG    1 
ATOM   11650 C CD1   . TYR D 1 225 ? -46.440  -70.433  24.769  1.00 89.27  ? 225  TYR D CD1   1 
ATOM   11651 C CD2   . TYR D 1 225 ? -47.825  -72.373  24.410  1.00 87.45  ? 225  TYR D CD2   1 
ATOM   11652 C CE1   . TYR D 1 225 ? -47.459  -69.839  25.500  1.00 90.26  ? 225  TYR D CE1   1 
ATOM   11653 C CE2   . TYR D 1 225 ? -48.847  -71.790  25.144  1.00 87.45  ? 225  TYR D CE2   1 
ATOM   11654 C CZ    . TYR D 1 225 ? -48.662  -70.520  25.680  1.00 103.08 ? 225  TYR D CZ    1 
ATOM   11655 O OH    . TYR D 1 225 ? -49.687  -69.973  26.401  1.00 105.34 ? 225  TYR D OH    1 
ATOM   11656 N N     . HIS D 1 226 ? -44.364  -72.871  26.676  1.00 43.88  ? 226  HIS D N     1 
ATOM   11657 C CA    . HIS D 1 226 ? -44.582  -73.611  27.915  1.00 42.85  ? 226  HIS D CA    1 
ATOM   11658 C C     . HIS D 1 226 ? -45.837  -73.207  28.700  1.00 43.19  ? 226  HIS D C     1 
ATOM   11659 O O     . HIS D 1 226 ? -46.040  -73.709  29.796  1.00 42.28  ? 226  HIS D O     1 
ATOM   11660 C CB    . HIS D 1 226 ? -43.317  -73.583  28.769  1.00 38.06  ? 226  HIS D CB    1 
ATOM   11661 C CG    . HIS D 1 226 ? -42.205  -74.341  28.158  1.00 43.36  ? 226  HIS D CG    1 
ATOM   11662 N ND1   . HIS D 1 226 ? -42.326  -75.675  27.826  1.00 46.29  ? 226  HIS D ND1   1 
ATOM   11663 C CD2   . HIS D 1 226 ? -40.957  -73.989  27.848  1.00 45.93  ? 226  HIS D CD2   1 
ATOM   11664 C CE1   . HIS D 1 226 ? -41.187  -76.108  27.311  1.00 46.31  ? 226  HIS D CE1   1 
ATOM   11665 N NE2   . HIS D 1 226 ? -40.340  -75.102  27.309  1.00 56.70  ? 226  HIS D NE2   1 
ATOM   11666 N N     . GLY D 1 227 ? -46.713  -72.372  28.136  1.00 59.29  ? 227  GLY D N     1 
ATOM   11667 C CA    . GLY D 1 227 ? -47.902  -71.860  28.820  1.00 75.51  ? 227  GLY D CA    1 
ATOM   11668 C C     . GLY D 1 227 ? -47.798  -70.365  29.160  1.00 91.74  ? 227  GLY D C     1 
ATOM   11669 O O     . GLY D 1 227 ? -46.693  -69.813  29.209  1.00 70.66  ? 227  GLY D O     1 
ATOM   11670 N N     . ALA D 1 228 ? -48.958  -69.722  29.409  1.00 106.74 ? 228  ALA D N     1 
ATOM   11671 C CA    . ALA D 1 228 ? -49.027  -68.314  29.795  1.00 112.05 ? 228  ALA D CA    1 
ATOM   11672 C C     . ALA D 1 228 ? -48.359  -68.128  31.156  1.00 119.70 ? 228  ALA D C     1 
ATOM   11673 O O     . ALA D 1 228 ? -48.367  -69.059  31.954  1.00 134.60 ? 228  ALA D O     1 
ATOM   11674 C CB    . ALA D 1 228 ? -50.466  -67.839  29.803  1.00 94.04  ? 228  ALA D CB    1 
ATOM   11675 N N     . PRO D 1 229 ? -47.756  -66.955  31.492  1.00 115.94 ? 229  PRO D N     1 
ATOM   11676 C CA    . PRO D 1 229 ? -47.155  -66.789  32.819  1.00 108.96 ? 229  PRO D CA    1 
ATOM   11677 C C     . PRO D 1 229 ? -48.204  -66.798  33.941  1.00 101.42 ? 229  PRO D C     1 
ATOM   11678 O O     . PRO D 1 229 ? -49.341  -66.344  33.760  1.00 70.85  ? 229  PRO D O     1 
ATOM   11679 C CB    . PRO D 1 229 ? -46.225  -65.579  32.691  1.00 100.12 ? 229  PRO D CB    1 
ATOM   11680 C CG    . PRO D 1 229 ? -46.704  -64.872  31.415  1.00 102.70 ? 229  PRO D CG    1 
ATOM   11681 C CD    . PRO D 1 229 ? -47.673  -65.745  30.651  1.00 99.77  ? 229  PRO D CD    1 
ATOM   11682 N N     . ASN D 1 230 ? -47.848  -67.400  35.085  1.00 94.54  ? 230  ASN D N     1 
ATOM   11683 C CA    . ASN D 1 230 ? -48.800  -67.641  36.165  1.00 87.31  ? 230  ASN D CA    1 
ATOM   11684 C C     . ASN D 1 230 ? -49.719  -68.835  35.891  1.00 77.74  ? 230  ASN D C     1 
ATOM   11685 O O     . ASN D 1 230 ? -50.511  -69.175  36.761  1.00 77.45  ? 230  ASN D O     1 
ATOM   11686 C CB    . ASN D 1 230 ? -49.557  -66.393  36.618  1.00 89.08  ? 230  ASN D CB    1 
ATOM   11687 C CG    . ASN D 1 230 ? -48.732  -65.571  37.580  1.00 91.39  ? 230  ASN D CG    1 
ATOM   11688 O OD1   . ASN D 1 230 ? -48.512  -64.381  37.328  1.00 92.25  ? 230  ASN D OD1   1 
ATOM   11689 N ND2   . ASN D 1 230 ? -48.215  -66.191  38.631  1.00 81.68  ? 230  ASN D ND2   1 
ATOM   11690 N N     . GLU D 1 231 ? -49.588  -69.491  34.725  1.00 72.15  ? 231  GLU D N     1 
ATOM   11691 C CA    . GLU D 1 231 ? -50.341  -70.708  34.456  1.00 63.05  ? 231  GLU D CA    1 
ATOM   11692 C C     . GLU D 1 231 ? -49.458  -71.952  34.556  1.00 49.28  ? 231  GLU D C     1 
ATOM   11693 O O     . GLU D 1 231 ? -48.247  -71.845  34.775  1.00 47.14  ? 231  GLU D O     1 
ATOM   11694 C CB    . GLU D 1 231 ? -51.134  -70.558  33.161  1.00 68.34  ? 231  GLU D CB    1 
ATOM   11695 C CG    . GLU D 1 231 ? -52.094  -69.374  33.253  1.00 88.55  ? 231  GLU D CG    1 
ATOM   11696 C CD    . GLU D 1 231 ? -53.375  -69.554  32.455  1.00 98.81  ? 231  GLU D CD    1 
ATOM   11697 O OE1   . GLU D 1 231 ? -54.467  -69.092  32.853  1.00 100.08 ? 231  GLU D OE1   1 
ATOM   11698 O OE2   . GLU D 1 231 ? -53.245  -70.238  31.430  1.00 103.68 ? 231  GLU D OE2   1 
ATOM   11699 N N     . LYS D 1 232 ? -50.087  -73.128  34.483  1.00 41.90  ? 232  LYS D N     1 
ATOM   11700 C CA    . LYS D 1 232 ? -49.383  -74.401  34.553  1.00 38.78  ? 232  LYS D CA    1 
ATOM   11701 C C     . LYS D 1 232 ? -48.356  -74.475  33.411  1.00 39.99  ? 232  LYS D C     1 
ATOM   11702 O O     . LYS D 1 232 ? -48.660  -74.147  32.249  1.00 34.42  ? 232  LYS D O     1 
ATOM   11703 C CB    . LYS D 1 232 ? -50.428  -75.506  34.375  1.00 31.48  ? 232  LYS D CB    1 
ATOM   11704 C CG    . LYS D 1 232 ? -49.902  -76.902  34.616  1.00 37.85  ? 232  LYS D CG    1 
ATOM   11705 C CD    . LYS D 1 232 ? -50.772  -77.934  33.919  1.00 32.83  ? 232  LYS D CD    1 
ATOM   11706 C CE    . LYS D 1 232 ? -50.322  -79.336  34.145  1.00 27.72  ? 232  LYS D CE    1 
ATOM   11707 N NZ    . LYS D 1 232 ? -51.317  -80.309  33.667  1.00 22.44  ? 232  LYS D NZ    1 
ATOM   11708 N N     . TYR D 1 233 ? -47.128  -74.880  33.758  1.00 33.83  ? 233  TYR D N     1 
ATOM   11709 C CA    . TYR D 1 233 ? -46.124  -75.190  32.753  1.00 31.37  ? 233  TYR D CA    1 
ATOM   11710 C C     . TYR D 1 233 ? -46.476  -76.475  32.002  1.00 28.81  ? 233  TYR D C     1 
ATOM   11711 O O     . TYR D 1 233 ? -46.712  -77.515  32.621  1.00 26.43  ? 233  TYR D O     1 
ATOM   11712 C CB    . TYR D 1 233 ? -44.831  -75.425  33.519  1.00 32.03  ? 233  TYR D CB    1 
ATOM   11713 C CG    . TYR D 1 233 ? -43.645  -75.772  32.631  1.00 34.77  ? 233  TYR D CG    1 
ATOM   11714 C CD1   . TYR D 1 233 ? -43.442  -77.090  32.191  1.00 31.22  ? 233  TYR D CD1   1 
ATOM   11715 C CD2   . TYR D 1 233 ? -42.718  -74.795  32.235  1.00 30.98  ? 233  TYR D CD2   1 
ATOM   11716 C CE1   . TYR D 1 233 ? -42.344  -77.426  31.415  1.00 29.18  ? 233  TYR D CE1   1 
ATOM   11717 C CE2   . TYR D 1 233 ? -41.612  -75.129  31.465  1.00 29.46  ? 233  TYR D CE2   1 
ATOM   11718 C CZ    . TYR D 1 233 ? -41.432  -76.444  31.051  1.00 29.82  ? 233  TYR D CZ    1 
ATOM   11719 O OH    . TYR D 1 233 ? -40.355  -76.783  30.298  1.00 29.23  ? 233  TYR D OH    1 
ATOM   11720 N N     . VAL D 1 234 ? -46.469  -76.402  30.664  1.00 23.47  ? 234  VAL D N     1 
ATOM   11721 C CA    . VAL D 1 234 ? -46.747  -77.557  29.825  1.00 25.43  ? 234  VAL D CA    1 
ATOM   11722 C C     . VAL D 1 234 ? -45.495  -77.895  29.025  1.00 24.66  ? 234  VAL D C     1 
ATOM   11723 O O     . VAL D 1 234 ? -44.889  -77.015  28.418  1.00 27.29  ? 234  VAL D O     1 
ATOM   11724 C CB    . VAL D 1 234 ? -47.922  -77.159  28.910  1.00 26.12  ? 234  VAL D CB    1 
ATOM   11725 C CG1   . VAL D 1 234 ? -48.265  -78.268  27.906  1.00 27.93  ? 234  VAL D CG1   1 
ATOM   11726 C CG2   . VAL D 1 234 ? -49.157  -76.903  29.764  1.00 26.88  ? 234  VAL D CG2   1 
ATOM   11727 N N     . ALA D 1 235 ? -45.110  -79.168  29.022  1.00 23.43  ? 235  ALA D N     1 
ATOM   11728 C CA    . ALA D 1 235 ? -43.967  -79.636  28.262  1.00 21.48  ? 235  ALA D CA    1 
ATOM   11729 C C     . ALA D 1 235 ? -44.340  -79.811  26.789  1.00 23.27  ? 235  ALA D C     1 
ATOM   11730 O O     . ALA D 1 235 ? -45.509  -79.649  26.412  1.00 23.65  ? 235  ALA D O     1 
ATOM   11731 C CB    . ALA D 1 235 ? -43.460  -80.926  28.880  1.00 19.42  ? 235  ALA D CB    1 
ATOM   11732 N N     . GLY D 1 236 ? -43.347  -80.190  25.957  1.00 22.30  ? 236  GLY D N     1 
ATOM   11733 C CA    . GLY D 1 236 ? -43.584  -80.422  24.531  1.00 21.20  ? 236  GLY D CA    1 
ATOM   11734 C C     . GLY D 1 236 ? -42.882  -81.689  24.035  1.00 19.70  ? 236  GLY D C     1 
ATOM   11735 O O     . GLY D 1 236 ? -41.944  -82.182  24.669  1.00 19.58  ? 236  GLY D O     1 
ATOM   11736 N N     . GLU D 1 237 ? -43.332  -82.213  22.887  1.00 17.53  ? 237  GLU D N     1 
ATOM   11737 C CA    . GLU D 1 237 ? -42.800  -83.462  22.357  1.00 18.02  ? 237  GLU D CA    1 
ATOM   11738 C C     . GLU D 1 237 ? -42.901  -83.416  20.839  1.00 20.08  ? 237  GLU D C     1 
ATOM   11739 O O     . GLU D 1 237 ? -43.889  -82.930  20.314  1.00 23.07  ? 237  GLU D O     1 
ATOM   11740 C CB    . GLU D 1 237 ? -43.619  -84.638  22.893  1.00 17.48  ? 237  GLU D CB    1 
ATOM   11741 C CG    . GLU D 1 237 ? -42.993  -86.010  22.638  1.00 18.95  ? 237  GLU D CG    1 
ATOM   11742 C CD    . GLU D 1 237 ? -43.928  -87.146  23.033  1.00 24.54  ? 237  GLU D CD    1 
ATOM   11743 O OE1   . GLU D 1 237 ? -43.737  -87.838  24.074  1.00 26.10  ? 237  GLU D OE1   1 
ATOM   11744 O OE2   . GLU D 1 237 ? -44.913  -87.308  22.291  1.00 28.50  ? 237  GLU D OE2   1 
ATOM   11745 N N     . ILE D 1 238 ? -41.871  -83.898  20.129  1.00 22.52  ? 238  ILE D N     1 
ATOM   11746 C CA    . ILE D 1 238 ? -41.961  -84.109  18.693  1.00 20.21  ? 238  ILE D CA    1 
ATOM   11747 C C     . ILE D 1 238 ? -41.818  -85.603  18.395  1.00 21.66  ? 238  ILE D C     1 
ATOM   11748 O O     . ILE D 1 238 ? -41.361  -86.374  19.242  1.00 22.21  ? 238  ILE D O     1 
ATOM   11749 C CB    . ILE D 1 238 ? -40.951  -83.239  17.926  1.00 21.11  ? 238  ILE D CB    1 
ATOM   11750 C CG1   . ILE D 1 238 ? -39.548  -83.686  18.133  1.00 26.48  ? 238  ILE D CG1   1 
ATOM   11751 C CG2   . ILE D 1 238 ? -41.078  -81.757  18.263  1.00 18.56  ? 238  ILE D CG2   1 
ATOM   11752 C CD1   . ILE D 1 238 ? -38.528  -82.824  17.392  1.00 29.44  ? 238  ILE D CD1   1 
ATOM   11753 N N     . SER D 1 239 ? -42.167  -86.000  17.166  1.00 21.29  ? 239  SER D N     1 
ATOM   11754 C CA    . SER D 1 239 ? -42.261  -87.387  16.732  1.00 25.50  ? 239  SER D CA    1 
ATOM   11755 C C     . SER D 1 239 ? -41.589  -87.549  15.377  1.00 25.97  ? 239  SER D C     1 
ATOM   11756 O O     . SER D 1 239 ? -41.728  -86.668  14.539  1.00 24.95  ? 239  SER D O     1 
ATOM   11757 C CB    . SER D 1 239 ? -43.700  -87.776  16.555  1.00 31.67  ? 239  SER D CB    1 
ATOM   11758 O OG    . SER D 1 239 ? -44.164  -88.202  17.816  1.00 41.50  ? 239  SER D OG    1 
ATOM   11759 N N     . ILE D 1 240 ? -40.942  -88.701  15.138  1.00 21.12  ? 240  ILE D N     1 
ATOM   11760 C CA    . ILE D 1 240 ? -40.410  -88.949  13.818  1.00 22.34  ? 240  ILE D CA    1 
ATOM   11761 C C     . ILE D 1 240 ? -40.699  -90.407  13.486  1.00 21.72  ? 240  ILE D C     1 
ATOM   11762 O O     . ILE D 1 240 ? -40.520  -91.279  14.328  1.00 20.94  ? 240  ILE D O     1 
ATOM   11763 C CB    . ILE D 1 240 ? -38.907  -88.574  13.727  1.00 26.64  ? 240  ILE D CB    1 
ATOM   11764 C CG1   . ILE D 1 240 ? -38.401  -88.688  12.285  1.00 31.93  ? 240  ILE D CG1   1 
ATOM   11765 C CG2   . ILE D 1 240 ? -38.021  -89.409  14.677  1.00 20.40  ? 240  ILE D CG2   1 
ATOM   11766 C CD1   . ILE D 1 240 ? -36.925  -88.367  12.117  1.00 37.97  ? 240  ILE D CD1   1 
ATOM   11767 N N     . THR D 1 241 ? -41.154  -90.680  12.262  1.00 20.51  ? 241  THR D N     1 
ATOM   11768 C CA    . THR D 1 241 ? -41.252  -92.052  11.801  1.00 21.22  ? 241  THR D CA    1 
ATOM   11769 C C     . THR D 1 241 ? -40.145  -92.289  10.764  1.00 19.58  ? 241  THR D C     1 
ATOM   11770 O O     . THR D 1 241 ? -39.631  -91.341  10.172  1.00 19.84  ? 241  THR D O     1 
ATOM   11771 C CB    . THR D 1 241 ? -42.667  -92.321  11.271  1.00 21.86  ? 241  THR D CB    1 
ATOM   11772 O OG1   . THR D 1 241 ? -42.757  -93.751  11.159  1.00 23.70  ? 241  THR D OG1   1 
ATOM   11773 C CG2   . THR D 1 241 ? -42.987  -91.547  10.001  1.00 19.04  ? 241  THR D CG2   1 
ATOM   11774 N N     . LEU D 1 242 ? -39.744  -93.543  10.557  1.00 18.34  ? 242  LEU D N     1 
ATOM   11775 C CA    . LEU D 1 242 ? -38.546  -93.834  9.767   1.00 22.07  ? 242  LEU D CA    1 
ATOM   11776 C C     . LEU D 1 242 ? -38.786  -93.643  8.272   1.00 21.50  ? 242  LEU D C     1 
ATOM   11777 O O     . LEU D 1 242 ? -37.873  -93.202  7.564   1.00 21.24  ? 242  LEU D O     1 
ATOM   11778 C CB    . LEU D 1 242 ? -37.981  -95.212  10.086  1.00 19.74  ? 242  LEU D CB    1 
ATOM   11779 C CG    . LEU D 1 242 ? -37.559  -95.386  11.557  1.00 22.58  ? 242  LEU D CG    1 
ATOM   11780 C CD1   . LEU D 1 242 ? -37.120  -96.847  11.856  1.00 22.30  ? 242  LEU D CD1   1 
ATOM   11781 C CD2   . LEU D 1 242 ? -36.537  -94.364  12.017  1.00 19.12  ? 242  LEU D CD2   1 
ATOM   11782 N N     . ASN D 1 243 ? -39.995  -94.012  7.795   1.00 19.70  ? 243  ASN D N     1 
ATOM   11783 C CA    . ASN D 1 243 ? -40.338  -93.752  6.398   1.00 18.72  ? 243  ASN D CA    1 
ATOM   11784 C C     . ASN D 1 243 ? -41.510  -92.780  6.401   1.00 20.09  ? 243  ASN D C     1 
ATOM   11785 O O     . ASN D 1 243 ? -41.549  -91.883  7.247   1.00 22.88  ? 243  ASN D O     1 
ATOM   11786 C CB    . ASN D 1 243 ? -40.460  -95.033  5.577   1.00 18.38  ? 243  ASN D CB    1 
ATOM   11787 C CG    . ASN D 1 243 ? -41.457  -96.015  6.155   1.00 19.74  ? 243  ASN D CG    1 
ATOM   11788 O OD1   . ASN D 1 243 ? -42.254  -95.633  7.017   1.00 18.42  ? 243  ASN D OD1   1 
ATOM   11789 N ND2   . ASN D 1 243 ? -41.468  -97.261  5.662   1.00 16.99  ? 243  ASN D ND2   1 
ATOM   11790 N N     . GLN D 1 244 ? -42.472  -92.964  5.498   1.00 20.81  ? 244  GLN D N     1 
ATOM   11791 C CA    . GLN D 1 244 ? -43.585  -92.025  5.396   1.00 20.93  ? 244  GLN D CA    1 
ATOM   11792 C C     . GLN D 1 244 ? -44.783  -92.489  6.238   1.00 20.79  ? 244  GLN D C     1 
ATOM   11793 O O     . GLN D 1 244 ? -45.724  -91.723  6.410   1.00 20.66  ? 244  GLN D O     1 
ATOM   11794 C CB    . GLN D 1 244 ? -43.993  -91.908  3.921   1.00 22.58  ? 244  GLN D CB    1 
ATOM   11795 C CG    . GLN D 1 244 ? -43.015  -91.143  3.036   1.00 25.56  ? 244  GLN D CG    1 
ATOM   11796 C CD    . GLN D 1 244 ? -42.927  -89.698  3.470   1.00 27.10  ? 244  GLN D CD    1 
ATOM   11797 O OE1   . GLN D 1 244 ? -43.917  -88.958  3.419   1.00 29.09  ? 244  GLN D OE1   1 
ATOM   11798 N NE2   . GLN D 1 244 ? -41.775  -89.307  3.991   1.00 21.75  ? 244  GLN D NE2   1 
ATOM   11799 N N     . HIS D 1 245 ? -44.744  -93.723  6.776   1.00 18.92  ? 245  HIS D N     1 
ATOM   11800 C CA    . HIS D 1 245 ? -45.901  -94.303  7.439   1.00 19.25  ? 245  HIS D CA    1 
ATOM   11801 C C     . HIS D 1 245 ? -45.583  -94.615  8.904   1.00 18.26  ? 245  HIS D C     1 
ATOM   11802 O O     . HIS D 1 245 ? -44.439  -94.823  9.263   1.00 18.47  ? 245  HIS D O     1 
ATOM   11803 C CB    . HIS D 1 245 ? -46.368  -95.538  6.662   1.00 18.24  ? 245  HIS D CB    1 
ATOM   11804 C CG    . HIS D 1 245 ? -46.801  -95.194  5.282   1.00 21.39  ? 245  HIS D CG    1 
ATOM   11805 N ND1   . HIS D 1 245 ? -45.904  -95.066  4.240   1.00 23.17  ? 245  HIS D ND1   1 
ATOM   11806 C CD2   . HIS D 1 245 ? -48.029  -94.904  4.768   1.00 21.36  ? 245  HIS D CD2   1 
ATOM   11807 C CE1   . HIS D 1 245 ? -46.570  -94.743  3.127   1.00 23.03  ? 245  HIS D CE1   1 
ATOM   11808 N NE2   . HIS D 1 245 ? -47.868  -94.620  3.430   1.00 22.87  ? 245  HIS D NE2   1 
ATOM   11809 N N     . TRP D 1 246 ? -46.611  -94.693  9.746   1.00 18.48  ? 246  TRP D N     1 
ATOM   11810 C CA    . TRP D 1 246 ? -46.463  -95.030  11.155  1.00 17.79  ? 246  TRP D CA    1 
ATOM   11811 C C     . TRP D 1 246 ? -46.596  -96.536  11.370  1.00 17.95  ? 246  TRP D C     1 
ATOM   11812 O O     . TRP D 1 246 ? -45.744  -97.138  12.028  1.00 20.37  ? 246  TRP D O     1 
ATOM   11813 C CB    . TRP D 1 246 ? -47.437  -94.218  12.009  1.00 17.23  ? 246  TRP D CB    1 
ATOM   11814 C CG    . TRP D 1 246 ? -47.135  -92.751  11.852  1.00 21.69  ? 246  TRP D CG    1 
ATOM   11815 C CD1   . TRP D 1 246 ? -47.560  -91.944  10.829  1.00 21.30  ? 246  TRP D CD1   1 
ATOM   11816 C CD2   . TRP D 1 246 ? -46.286  -91.934  12.691  1.00 20.28  ? 246  TRP D CD2   1 
ATOM   11817 N NE1   . TRP D 1 246 ? -47.035  -90.689  10.977  1.00 21.86  ? 246  TRP D NE1   1 
ATOM   11818 C CE2   . TRP D 1 246 ? -46.268  -90.638  12.114  1.00 22.13  ? 246  TRP D CE2   1 
ATOM   11819 C CE3   . TRP D 1 246 ? -45.576  -92.150  13.877  1.00 18.63  ? 246  TRP D CE3   1 
ATOM   11820 C CZ2   . TRP D 1 246 ? -45.523  -89.577  12.657  1.00 20.05  ? 246  TRP D CZ2   1 
ATOM   11821 C CZ3   . TRP D 1 246 ? -44.869  -91.092  14.433  1.00 20.76  ? 246  TRP D CZ3   1 
ATOM   11822 C CH2   . TRP D 1 246 ? -44.843  -89.826  13.831  1.00 19.82  ? 246  TRP D CH2   1 
ATOM   11823 N N     . GLY D 1 247 ? -47.659  -97.142  10.863  1.00 16.59  ? 247  GLY D N     1 
ATOM   11824 C CA    . GLY D 1 247 ? -47.717  -98.597  10.799  1.00 16.16  ? 247  GLY D CA    1 
ATOM   11825 C C     . GLY D 1 247 ? -46.773  -99.094  9.709   1.00 18.09  ? 247  GLY D C     1 
ATOM   11826 O O     . GLY D 1 247 ? -46.362  -98.309  8.855   1.00 20.44  ? 247  GLY D O     1 
ATOM   11827 N N     . ILE D 1 248 ? -46.438  -100.383 9.724   1.00 18.30  ? 248  ILE D N     1 
ATOM   11828 C CA    . ILE D 1 248 ? -45.536  -100.947 8.737   1.00 20.08  ? 248  ILE D CA    1 
ATOM   11829 C C     . ILE D 1 248 ? -46.114  -100.796 7.324   1.00 23.07  ? 248  ILE D C     1 
ATOM   11830 O O     . ILE D 1 248 ? -47.329  -100.871 7.095   1.00 22.39  ? 248  ILE D O     1 
ATOM   11831 C CB    . ILE D 1 248 ? -45.264  -102.410 9.113   1.00 21.44  ? 248  ILE D CB    1 
ATOM   11832 C CG1   . ILE D 1 248 ? -44.108  -103.003 8.283   1.00 19.95  ? 248  ILE D CG1   1 
ATOM   11833 C CG2   . ILE D 1 248 ? -46.552  -103.237 9.033   1.00 16.48  ? 248  ILE D CG2   1 
ATOM   11834 C CD1   . ILE D 1 248 ? -43.575  -104.314 8.868   1.00 19.62  ? 248  ILE D CD1   1 
ATOM   11835 N N     . ALA D 1 249 ? -45.211  -100.551 6.366   1.00 24.43  ? 249  ALA D N     1 
ATOM   11836 C CA    . ALA D 1 249 ? -45.563  -100.342 4.974   1.00 23.59  ? 249  ALA D CA    1 
ATOM   11837 C C     . ALA D 1 249 ? -44.426  -100.893 4.113   1.00 24.78  ? 249  ALA D C     1 
ATOM   11838 O O     . ALA D 1 249 ? -43.397  -100.232 3.916   1.00 24.67  ? 249  ALA D O     1 
ATOM   11839 C CB    . ALA D 1 249 ? -45.763  -98.864  4.761   1.00 19.59  ? 249  ALA D CB    1 
ATOM   11840 N N     . ALA D 1 250 ? -44.642  -102.109 3.612   1.00 22.47  ? 250  ALA D N     1 
ATOM   11841 C CA    . ALA D 1 250 ? -43.616  -102.946 3.009   1.00 21.12  ? 250  ALA D CA    1 
ATOM   11842 C C     . ALA D 1 250 ? -43.001  -102.273 1.792   1.00 22.12  ? 250  ALA D C     1 
ATOM   11843 O O     . ALA D 1 250 ? -41.806  -102.424 1.576   1.00 23.65  ? 250  ALA D O     1 
ATOM   11844 C CB    . ALA D 1 250 ? -44.198  -104.317 2.640   1.00 18.52  ? 250  ALA D CB    1 
ATOM   11845 N N     . ASN D 1 251 ? -43.809  -101.577 0.973   1.00 25.69  ? 251  ASN D N     1 
ATOM   11846 C CA    . ASN D 1 251 ? -43.276  -100.937 -0.221  1.00 23.62  ? 251  ASN D CA    1 
ATOM   11847 C C     . ASN D 1 251 ? -43.095  -99.428  -0.055  1.00 22.29  ? 251  ASN D C     1 
ATOM   11848 O O     . ASN D 1 251 ? -43.110  -98.691  -1.045  1.00 24.25  ? 251  ASN D O     1 
ATOM   11849 C CB    . ASN D 1 251 ? -44.076  -101.298 -1.460  1.00 24.70  ? 251  ASN D CB    1 
ATOM   11850 C CG    . ASN D 1 251 ? -43.861  -102.757 -1.818  1.00 33.00  ? 251  ASN D CG    1 
ATOM   11851 O OD1   . ASN D 1 251 ? -42.741  -103.314 -1.748  1.00 33.07  ? 251  ASN D OD1   1 
ATOM   11852 N ND2   . ASN D 1 251 ? -44.953  -103.405 -2.176  1.00 27.43  ? 251  ASN D ND2   1 
ATOM   11853 N N     . ASP D 1 252 ? -42.955  -98.973  1.183   1.00 18.70  ? 252  ASP D N     1 
ATOM   11854 C CA    . ASP D 1 252 ? -42.496  -97.606  1.418   1.00 21.69  ? 252  ASP D CA    1 
ATOM   11855 C C     . ASP D 1 252 ? -40.966  -97.684  1.605   1.00 24.17  ? 252  ASP D C     1 
ATOM   11856 O O     . ASP D 1 252 ? -40.479  -98.080  2.684   1.00 24.61  ? 252  ASP D O     1 
ATOM   11857 C CB    . ASP D 1 252 ? -43.218  -96.971  2.603   1.00 18.14  ? 252  ASP D CB    1 
ATOM   11858 C CG    . ASP D 1 252 ? -42.698  -95.611  3.014   1.00 23.30  ? 252  ASP D CG    1 
ATOM   11859 O OD1   . ASP D 1 252 ? -41.725  -95.154  2.373   1.00 25.08  ? 252  ASP D OD1   1 
ATOM   11860 O OD2   . ASP D 1 252 ? -43.268  -94.993  3.962   1.00 22.36  ? 252  ASP D OD2   1 
ATOM   11861 N N     . LEU D 1 253 ? -40.217  -97.344  0.540   1.00 19.19  ? 253  LEU D N     1 
ATOM   11862 C CA    . LEU D 1 253 ? -38.763  -97.390  0.532   1.00 18.22  ? 253  LEU D CA    1 
ATOM   11863 C C     . LEU D 1 253 ? -38.205  -96.015  0.911   1.00 23.06  ? 253  LEU D C     1 
ATOM   11864 O O     . LEU D 1 253 ? -36.983  -95.813  0.933   1.00 26.19  ? 253  LEU D O     1 
ATOM   11865 C CB    . LEU D 1 253 ? -38.292  -97.784  -0.870  1.00 18.19  ? 253  LEU D CB    1 
ATOM   11866 C CG    . LEU D 1 253 ? -39.014  -98.980  -1.516  1.00 17.93  ? 253  LEU D CG    1 
ATOM   11867 C CD1   . LEU D 1 253 ? -38.317  -99.379  -2.807  1.00 16.50  ? 253  LEU D CD1   1 
ATOM   11868 C CD2   . LEU D 1 253 ? -39.087  -100.186 -0.520  1.00 15.80  ? 253  LEU D CD2   1 
ATOM   11869 N N     . ASN D 1 254 ? -39.088  -95.038  1.158   1.00 18.99  ? 254  ASN D N     1 
ATOM   11870 C CA    . ASN D 1 254 ? -38.626  -93.677  1.354   1.00 19.12  ? 254  ASN D CA    1 
ATOM   11871 C C     . ASN D 1 254 ? -38.198  -93.446  2.813   1.00 19.81  ? 254  ASN D C     1 
ATOM   11872 O O     . ASN D 1 254 ? -38.795  -92.635  3.533   1.00 18.17  ? 254  ASN D O     1 
ATOM   11873 C CB    . ASN D 1 254 ? -39.698  -92.713  0.858   1.00 20.40  ? 254  ASN D CB    1 
ATOM   11874 C CG    . ASN D 1 254 ? -39.222  -91.288  0.837   1.00 22.52  ? 254  ASN D CG    1 
ATOM   11875 O OD1   . ASN D 1 254 ? -38.016  -91.026  0.918   1.00 23.21  ? 254  ASN D OD1   1 
ATOM   11876 N ND2   . ASN D 1 254 ? -40.155  -90.362  0.722   1.00 24.78  ? 254  ASN D ND2   1 
ATOM   11877 N N     . TYR D 1 255 ? -37.169  -94.172  3.268   1.00 20.00  ? 255  TYR D N     1 
ATOM   11878 C CA    . TYR D 1 255 ? -36.647  -94.030  4.630   1.00 19.91  ? 255  TYR D CA    1 
ATOM   11879 C C     . TYR D 1 255 ? -35.768  -92.790  4.733   1.00 20.89  ? 255  TYR D C     1 
ATOM   11880 O O     . TYR D 1 255 ? -35.085  -92.434  3.762   1.00 18.51  ? 255  TYR D O     1 
ATOM   11881 C CB    . TYR D 1 255 ? -35.786  -95.252  4.932   1.00 19.97  ? 255  TYR D CB    1 
ATOM   11882 C CG    . TYR D 1 255 ? -36.613  -96.427  5.424   1.00 23.01  ? 255  TYR D CG    1 
ATOM   11883 C CD1   . TYR D 1 255 ? -37.350  -97.209  4.523   1.00 22.74  ? 255  TYR D CD1   1 
ATOM   11884 C CD2   . TYR D 1 255 ? -36.689  -96.727  6.789   1.00 20.80  ? 255  TYR D CD2   1 
ATOM   11885 C CE1   . TYR D 1 255 ? -38.111  -98.276  4.977   1.00 21.87  ? 255  TYR D CE1   1 
ATOM   11886 C CE2   . TYR D 1 255 ? -37.470  -97.778  7.249   1.00 20.15  ? 255  TYR D CE2   1 
ATOM   11887 C CZ    . TYR D 1 255 ? -38.152  -98.556  6.333   1.00 21.02  ? 255  TYR D CZ    1 
ATOM   11888 O OH    . TYR D 1 255 ? -38.891  -99.586  6.756   1.00 23.68  ? 255  TYR D OH    1 
ATOM   11889 N N     . LYS D 1 256 ? -35.828  -92.115  5.894   1.00 21.18  ? 256  LYS D N     1 
ATOM   11890 C CA    . LYS D 1 256 ? -34.941  -90.992  6.173   1.00 21.37  ? 256  LYS D CA    1 
ATOM   11891 C C     . LYS D 1 256 ? -33.537  -91.546  6.441   1.00 21.92  ? 256  LYS D C     1 
ATOM   11892 O O     . LYS D 1 256 ? -33.391  -92.732  6.764   1.00 20.91  ? 256  LYS D O     1 
ATOM   11893 C CB    . LYS D 1 256 ? -35.494  -90.322  7.432   1.00 23.08  ? 256  LYS D CB    1 
ATOM   11894 C CG    . LYS D 1 256 ? -36.879  -89.719  7.232   1.00 24.46  ? 256  LYS D CG    1 
ATOM   11895 C CD    . LYS D 1 256 ? -37.482  -89.180  8.526   1.00 24.01  ? 256  LYS D CD    1 
ATOM   11896 C CE    . LYS D 1 256 ? -38.905  -88.691  8.326   1.00 24.24  ? 256  LYS D CE    1 
ATOM   11897 N NZ    . LYS D 1 256 ? -39.753  -89.771  7.771   1.00 22.95  ? 256  LYS D NZ    1 
ATOM   11898 N N     . SER D 1 257 ? -32.499  -90.718  6.310   1.00 19.54  ? 257  SER D N     1 
ATOM   11899 C CA    . SER D 1 257 ? -31.177  -91.198  6.693   1.00 19.97  ? 257  SER D CA    1 
ATOM   11900 C C     . SER D 1 257 ? -31.080  -91.338  8.211   1.00 18.52  ? 257  SER D C     1 
ATOM   11901 O O     . SER D 1 257 ? -31.673  -90.552  8.952   1.00 17.03  ? 257  SER D O     1 
ATOM   11902 C CB    . SER D 1 257 ? -30.074  -90.283  6.186   1.00 18.99  ? 257  SER D CB    1 
ATOM   11903 O OG    . SER D 1 257 ? -30.149  -89.058  6.896   1.00 19.94  ? 257  SER D OG    1 
ATOM   11904 N N     . PRO D 1 258 ? -30.284  -92.310  8.703   1.00 21.08  ? 258  PRO D N     1 
ATOM   11905 C CA    . PRO D 1 258 ? -29.900  -92.334  10.111  1.00 20.11  ? 258  PRO D CA    1 
ATOM   11906 C C     . PRO D 1 258 ? -29.368  -90.986  10.599  1.00 22.70  ? 258  PRO D C     1 
ATOM   11907 O O     . PRO D 1 258 ? -29.650  -90.580  11.730  1.00 22.73  ? 258  PRO D O     1 
ATOM   11908 C CB    . PRO D 1 258 ? -28.955  -93.542  10.212  1.00 20.61  ? 258  PRO D CB    1 
ATOM   11909 C CG    . PRO D 1 258 ? -29.396  -94.429  9.022   1.00 18.94  ? 258  PRO D CG    1 
ATOM   11910 C CD    . PRO D 1 258 ? -29.762  -93.463  7.928   1.00 19.80  ? 258  PRO D CD    1 
ATOM   11911 N N     . ALA D 1 259 ? -28.660  -90.251  9.724   1.00 21.21  ? 259  ALA D N     1 
ATOM   11912 C CA    . ALA D 1 259 ? -28.117  -88.945  10.104  1.00 22.09  ? 259  ALA D CA    1 
ATOM   11913 C C     . ALA D 1 259 ? -29.248  -87.973  10.451  1.00 23.90  ? 259  ALA D C     1 
ATOM   11914 O O     . ALA D 1 259 ? -29.162  -87.241  11.438  1.00 22.01  ? 259  ALA D O     1 
ATOM   11915 C CB    . ALA D 1 259 ? -27.220  -88.360  9.017   1.00 17.06  ? 259  ALA D CB    1 
ATOM   11916 N N     . GLU D 1 260 ? -30.302  -87.960  9.615   1.00 25.71  ? 260  GLU D N     1 
ATOM   11917 C CA    . GLU D 1 260 ? -31.416  -87.063  9.852   1.00 22.40  ? 260  GLU D CA    1 
ATOM   11918 C C     . GLU D 1 260 ? -32.102  -87.440  11.170  1.00 20.62  ? 260  GLU D C     1 
ATOM   11919 O O     . GLU D 1 260 ? -32.538  -86.576  11.939  1.00 19.73  ? 260  GLU D O     1 
ATOM   11920 C CB    . GLU D 1 260 ? -32.378  -87.062  8.661   1.00 25.15  ? 260  GLU D CB    1 
ATOM   11921 C CG    . GLU D 1 260 ? -33.613  -86.205  8.960   1.00 26.73  ? 260  GLU D CG    1 
ATOM   11922 C CD    . GLU D 1 260 ? -34.700  -86.128  7.894   1.00 35.33  ? 260  GLU D CD    1 
ATOM   11923 O OE1   . GLU D 1 260 ? -34.486  -86.619  6.750   1.00 34.46  ? 260  GLU D OE1   1 
ATOM   11924 O OE2   . GLU D 1 260 ? -35.778  -85.567  8.209   1.00 36.37  ? 260  GLU D OE2   1 
ATOM   11925 N N     . MET D 1 261 ? -32.186  -88.744  11.443  1.00 18.58  ? 261  MET D N     1 
ATOM   11926 C CA    . MET D 1 261 ? -32.750  -89.209  12.703  1.00 20.37  ? 261  MET D CA    1 
ATOM   11927 C C     . MET D 1 261 ? -31.959  -88.646  13.902  1.00 19.43  ? 261  MET D C     1 
ATOM   11928 O O     . MET D 1 261 ? -32.550  -88.078  14.823  1.00 19.23  ? 261  MET D O     1 
ATOM   11929 C CB    . MET D 1 261 ? -32.856  -90.734  12.685  1.00 21.96  ? 261  MET D CB    1 
ATOM   11930 C CG    . MET D 1 261 ? -33.192  -91.330  14.058  1.00 30.83  ? 261  MET D CG    1 
ATOM   11931 S SD    . MET D 1 261 ? -33.051  -93.139  14.101  1.00 35.86  ? 261  MET D SD    1 
ATOM   11932 C CE    . MET D 1 261 ? -31.292  -93.364  13.780  1.00 30.30  ? 261  MET D CE    1 
ATOM   11933 N N     . ILE D 1 262 ? -30.619  -88.752  13.855  1.00 18.56  ? 262  ILE D N     1 
ATOM   11934 C CA    . ILE D 1 262 ? -29.789  -88.225  14.918  1.00 19.82  ? 262  ILE D CA    1 
ATOM   11935 C C     . ILE D 1 262 ? -29.968  -86.703  15.036  1.00 24.46  ? 262  ILE D C     1 
ATOM   11936 O O     . ILE D 1 262 ? -30.125  -86.183  16.144  1.00 21.61  ? 262  ILE D O     1 
ATOM   11937 C CB    . ILE D 1 262 ? -28.320  -88.641  14.749  1.00 19.49  ? 262  ILE D CB    1 
ATOM   11938 C CG1   . ILE D 1 262 ? -28.185  -90.121  15.031  1.00 18.16  ? 262  ILE D CG1   1 
ATOM   11939 C CG2   . ILE D 1 262 ? -27.392  -87.802  15.647  1.00 17.48  ? 262  ILE D CG2   1 
ATOM   11940 C CD1   . ILE D 1 262 ? -26.925  -90.736  14.467  1.00 17.53  ? 262  ILE D CD1   1 
ATOM   11941 N N     . GLU D 1 263 ? -29.977  -85.988  13.904  1.00 22.13  ? 263  GLU D N     1 
ATOM   11942 C CA    . GLU D 1 263 ? -30.171  -84.546  13.940  1.00 24.23  ? 263  GLU D CA    1 
ATOM   11943 C C     . GLU D 1 263 ? -31.516  -84.175  14.580  1.00 25.34  ? 263  GLU D C     1 
ATOM   11944 O O     . GLU D 1 263 ? -31.605  -83.143  15.262  1.00 21.51  ? 263  GLU D O     1 
ATOM   11945 C CB    . GLU D 1 263 ? -30.024  -83.896  12.572  1.00 21.13  ? 263  GLU D CB    1 
ATOM   11946 C CG    . GLU D 1 263 ? -28.587  -83.925  12.072  1.00 29.53  ? 263  GLU D CG    1 
ATOM   11947 C CD    . GLU D 1 263 ? -28.325  -83.066  10.812  1.00 41.15  ? 263  GLU D CD    1 
ATOM   11948 O OE1   . GLU D 1 263 ? -29.285  -82.385  10.354  1.00 39.29  ? 263  GLU D OE1   1 
ATOM   11949 O OE2   . GLU D 1 263 ? -27.171  -83.070  10.266  1.00 38.15  ? 263  GLU D OE2   1 
ATOM   11950 N N     . THR D 1 264 ? -32.557  -85.007  14.358  1.00 21.04  ? 264  THR D N     1 
ATOM   11951 C CA    . THR D 1 264 ? -33.884  -84.665  14.859  1.00 19.51  ? 264  THR D CA    1 
ATOM   11952 C C     . THR D 1 264 ? -33.909  -84.870  16.370  1.00 18.54  ? 264  THR D C     1 
ATOM   11953 O O     . THR D 1 264 ? -34.498  -84.063  17.087  1.00 18.51  ? 264  THR D O     1 
ATOM   11954 C CB    . THR D 1 264 ? -34.968  -85.482  14.151  1.00 19.95  ? 264  THR D CB    1 
ATOM   11955 O OG1   . THR D 1 264 ? -34.751  -85.242  12.769  1.00 20.05  ? 264  THR D OG1   1 
ATOM   11956 C CG2   . THR D 1 264 ? -36.370  -85.030  14.504  1.00 17.88  ? 264  THR D CG2   1 
ATOM   11957 N N     . VAL D 1 265 ? -33.262  -85.951  16.846  1.00 18.96  ? 265  VAL D N     1 
ATOM   11958 C CA    . VAL D 1 265 ? -33.170  -86.163  18.286  1.00 18.20  ? 265  VAL D CA    1 
ATOM   11959 C C     . VAL D 1 265 ? -32.468  -84.973  18.946  1.00 20.05  ? 265  VAL D C     1 
ATOM   11960 O O     . VAL D 1 265 ? -32.983  -84.408  19.914  1.00 20.12  ? 265  VAL D O     1 
ATOM   11961 C CB    . VAL D 1 265 ? -32.466  -87.494  18.607  1.00 16.33  ? 265  VAL D CB    1 
ATOM   11962 C CG1   . VAL D 1 265 ? -32.137  -87.618  20.092  1.00 15.10  ? 265  VAL D CG1   1 
ATOM   11963 C CG2   . VAL D 1 265 ? -33.314  -88.675  18.133  1.00 14.94  ? 265  VAL D CG2   1 
ATOM   11964 N N     . ALA D 1 266 ? -31.313  -84.558  18.393  1.00 19.52  ? 266  ALA D N     1 
ATOM   11965 C CA    . ALA D 1 266 ? -30.597  -83.441  18.988  1.00 18.96  ? 266  ALA D CA    1 
ATOM   11966 C C     . ALA D 1 266 ? -31.469  -82.181  18.950  1.00 20.85  ? 266  ALA D C     1 
ATOM   11967 O O     . ALA D 1 266 ? -31.493  -81.383  19.899  1.00 21.33  ? 266  ALA D O     1 
ATOM   11968 C CB    . ALA D 1 266 ? -29.299  -83.191  18.230  1.00 21.03  ? 266  ALA D CB    1 
ATOM   11969 N N     . HIS D 1 267 ? -32.186  -82.001  17.828  1.00 19.87  ? 267  HIS D N     1 
ATOM   11970 C CA    . HIS D 1 267 ? -32.980  -80.803  17.608  1.00 20.94  ? 267  HIS D CA    1 
ATOM   11971 C C     . HIS D 1 267 ? -34.107  -80.703  18.644  1.00 21.81  ? 267  HIS D C     1 
ATOM   11972 O O     . HIS D 1 267 ? -34.396  -79.611  19.124  1.00 22.32  ? 267  HIS D O     1 
ATOM   11973 C CB    . HIS D 1 267 ? -33.555  -80.813  16.179  1.00 21.05  ? 267  HIS D CB    1 
ATOM   11974 C CG    . HIS D 1 267 ? -34.474  -79.672  15.921  1.00 24.06  ? 267  HIS D CG    1 
ATOM   11975 N ND1   . HIS D 1 267 ? -34.056  -78.348  15.827  1.00 27.09  ? 267  HIS D ND1   1 
ATOM   11976 C CD2   . HIS D 1 267 ? -35.806  -79.657  15.778  1.00 24.49  ? 267  HIS D CD2   1 
ATOM   11977 C CE1   . HIS D 1 267 ? -35.111  -77.574  15.592  1.00 23.66  ? 267  HIS D CE1   1 
ATOM   11978 N NE2   . HIS D 1 267 ? -36.186  -78.352  15.543  1.00 22.97  ? 267  HIS D NE2   1 
ATOM   11979 N N     . ALA D 1 268 ? -34.715  -81.816  19.015  1.00 19.65  ? 268  ALA D N     1 
ATOM   11980 C CA    . ALA D 1 268 ? -35.767  -81.826  19.991  1.00 19.21  ? 268  ALA D CA    1 
ATOM   11981 C C     . ALA D 1 268 ? -35.265  -81.288  21.303  1.00 18.17  ? 268  ALA D C     1 
ATOM   11982 O O     . ALA D 1 268 ? -35.901  -80.534  21.914  1.00 18.52  ? 268  ALA D O     1 
ATOM   11983 C CB    . ALA D 1 268 ? -36.304  -83.237  20.180  1.00 16.61  ? 268  ALA D CB    1 
ATOM   11984 N N     . ARG D 1 269 ? -34.093  -81.683  21.714  1.00 19.24  ? 269  ARG D N     1 
ATOM   11985 C CA    . ARG D 1 269 ? -33.507  -81.200  22.925  1.00 19.15  ? 269  ARG D CA    1 
ATOM   11986 C C     . ARG D 1 269 ? -33.202  -79.727  22.861  1.00 20.04  ? 269  ARG D C     1 
ATOM   11987 O O     . ARG D 1 269 ? -33.387  -79.035  23.785  1.00 22.51  ? 269  ARG D O     1 
ATOM   11988 C CB    . ARG D 1 269 ? -32.292  -82.018  23.309  1.00 18.27  ? 269  ARG D CB    1 
ATOM   11989 C CG    . ARG D 1 269 ? -32.538  -83.495  23.361  1.00 17.54  ? 269  ARG D CG    1 
ATOM   11990 C CD    . ARG D 1 269 ? -33.772  -83.842  24.116  1.00 16.09  ? 269  ARG D CD    1 
ATOM   11991 N NE    . ARG D 1 269 ? -33.563  -83.864  25.526  1.00 18.09  ? 269  ARG D NE    1 
ATOM   11992 C CZ    . ARG D 1 269 ? -34.510  -83.807  26.435  1.00 20.18  ? 269  ARG D CZ    1 
ATOM   11993 N NH1   . ARG D 1 269 ? -35.747  -83.702  26.104  1.00 19.55  ? 269  ARG D NH1   1 
ATOM   11994 N NH2   . ARG D 1 269 ? -34.207  -83.873  27.676  1.00 16.81  ? 269  ARG D NH2   1 
ATOM   11995 N N     . HIS D 1 270 ? -32.742  -79.263  21.732  1.00 19.13  ? 270  HIS D N     1 
ATOM   11996 C CA    . HIS D 1 270 ? -32.445  -77.883  21.527  1.00 19.44  ? 270  HIS D CA    1 
ATOM   11997 C C     . HIS D 1 270 ? -33.669  -76.983  21.691  1.00 21.54  ? 270  HIS D C     1 
ATOM   11998 O O     . HIS D 1 270 ? -33.556  -75.914  22.190  1.00 21.99  ? 270  HIS D O     1 
ATOM   11999 C CB    . HIS D 1 270 ? -31.797  -77.689  20.175  1.00 18.78  ? 270  HIS D CB    1 
ATOM   12000 C CG    . HIS D 1 270 ? -31.539  -76.268  19.829  1.00 27.43  ? 270  HIS D CG    1 
ATOM   12001 N ND1   . HIS D 1 270 ? -31.792  -75.745  18.595  1.00 30.55  ? 270  HIS D ND1   1 
ATOM   12002 C CD2   . HIS D 1 270 ? -31.065  -75.251  20.570  1.00 26.46  ? 270  HIS D CD2   1 
ATOM   12003 C CE1   . HIS D 1 270 ? -31.464  -74.477  18.582  1.00 26.79  ? 270  HIS D CE1   1 
ATOM   12004 N NE2   . HIS D 1 270 ? -31.034  -74.152  19.773  1.00 25.85  ? 270  HIS D NE2   1 
ATOM   12005 N N     . ILE D 1 271 ? -34.824  -77.426  21.239  1.00 19.06  ? 271  ILE D N     1 
ATOM   12006 C CA    . ILE D 1 271 ? -36.041  -76.664  21.375  1.00 20.10  ? 271  ILE D CA    1 
ATOM   12007 C C     . ILE D 1 271 ? -36.806  -76.900  22.668  1.00 22.65  ? 271  ILE D C     1 
ATOM   12008 O O     . ILE D 1 271 ? -37.798  -76.311  22.879  1.00 24.15  ? 271  ILE D O     1 
ATOM   12009 C CB    . ILE D 1 271 ? -36.997  -76.816  20.178  1.00 20.04  ? 271  ILE D CB    1 
ATOM   12010 C CG1   . ILE D 1 271 ? -37.525  -78.231  20.057  1.00 15.54  ? 271  ILE D CG1   1 
ATOM   12011 C CG2   . ILE D 1 271 ? -36.349  -76.334  18.905  1.00 17.62  ? 271  ILE D CG2   1 
ATOM   12012 C CD1   . ILE D 1 271 ? -38.598  -78.398  19.049  1.00 15.06  ? 271  ILE D CD1   1 
ATOM   12013 N N     . GLY D 1 272 ? -36.285  -77.725  23.545  1.00 18.41  ? 272  GLY D N     1 
ATOM   12014 C CA    . GLY D 1 272 ? -36.922  -78.073  24.786  1.00 19.96  ? 272  GLY D CA    1 
ATOM   12015 C C     . GLY D 1 272 ? -38.048  -79.066  24.773  1.00 24.78  ? 272  GLY D C     1 
ATOM   12016 O O     . GLY D 1 272 ? -39.019  -78.902  25.423  1.00 25.37  ? 272  GLY D O     1 
ATOM   12017 N N     . ALA D 1 273 ? -37.903  -80.102  23.984  1.00 21.49  ? 273  ALA D N     1 
ATOM   12018 C CA    . ALA D 1 273 ? -38.957  -81.086  23.812  1.00 19.10  ? 273  ALA D CA    1 
ATOM   12019 C C     . ALA D 1 273 ? -38.366  -82.486  23.989  1.00 20.00  ? 273  ALA D C     1 
ATOM   12020 O O     . ALA D 1 273 ? -37.157  -82.677  23.857  1.00 19.38  ? 273  ALA D O     1 
ATOM   12021 C CB    . ALA D 1 273 ? -39.568  -80.940  22.422  1.00 16.63  ? 273  ALA D CB    1 
ATOM   12022 N N     . ASN D 1 274 ? -39.231  -83.453  24.299  1.00 17.41  ? 274  ASN D N     1 
ATOM   12023 C CA    . ASN D 1 274 ? -38.872  -84.843  24.141  1.00 18.18  ? 274  ASN D CA    1 
ATOM   12024 C C     . ASN D 1 274 ? -39.032  -85.230  22.661  1.00 18.48  ? 274  ASN D C     1 
ATOM   12025 O O     . ASN D 1 274 ? -39.644  -84.490  21.874  1.00 17.08  ? 274  ASN D O     1 
ATOM   12026 C CB    . ASN D 1 274 ? -39.761  -85.727  25.010  1.00 20.23  ? 274  ASN D CB    1 
ATOM   12027 C CG    . ASN D 1 274 ? -39.363  -85.726  26.468  1.00 20.46  ? 274  ASN D CG    1 
ATOM   12028 O OD1   . ASN D 1 274 ? -38.635  -84.828  26.929  1.00 19.63  ? 274  ASN D OD1   1 
ATOM   12029 N ND2   . ASN D 1 274 ? -39.847  -86.727  27.197  1.00 18.06  ? 274  ASN D ND2   1 
ATOM   12030 N N     . ILE D 1 275 ? -38.559  -86.386  22.304  1.00 15.60  ? 275  ILE D N     1 
ATOM   12031 C CA    . ILE D 1 275 ? -38.695  -86.930  20.997  1.00 16.18  ? 275  ILE D CA    1 
ATOM   12032 C C     . ILE D 1 275 ? -39.140  -88.395  21.043  1.00 18.12  ? 275  ILE D C     1 
ATOM   12033 O O     . ILE D 1 275 ? -38.670  -89.133  21.832  1.00 19.98  ? 275  ILE D O     1 
ATOM   12034 C CB    . ILE D 1 275 ? -37.373  -86.784  20.185  1.00 15.85  ? 275  ILE D CB    1 
ATOM   12035 C CG1   . ILE D 1 275 ? -37.412  -87.552  18.887  1.00 15.97  ? 275  ILE D CG1   1 
ATOM   12036 C CG2   . ILE D 1 275 ? -36.180  -87.266  20.949  1.00 13.61  ? 275  ILE D CG2   1 
ATOM   12037 C CD1   . ILE D 1 275 ? -38.036  -86.802  17.773  1.00 18.04  ? 275  ILE D CD1   1 
ATOM   12038 N N     . LEU D 1 276 ? -40.120  -88.762  20.243  1.00 17.80  ? 276  LEU D N     1 
ATOM   12039 C CA    . LEU D 1 276 ? -40.486  -90.156  20.030  1.00 19.74  ? 276  LEU D CA    1 
ATOM   12040 C C     . LEU D 1 276 ? -39.969  -90.611  18.667  1.00 20.74  ? 276  LEU D C     1 
ATOM   12041 O O     . LEU D 1 276 ? -40.212  -89.912  17.670  1.00 24.16  ? 276  LEU D O     1 
ATOM   12042 C CB    . LEU D 1 276 ? -42.010  -90.315  20.050  1.00 21.22  ? 276  LEU D CB    1 
ATOM   12043 C CG    . LEU D 1 276 ? -42.724  -90.082  21.375  1.00 24.33  ? 276  LEU D CG    1 
ATOM   12044 C CD1   . LEU D 1 276 ? -44.207  -90.349  21.164  1.00 21.97  ? 276  LEU D CD1   1 
ATOM   12045 C CD2   . LEU D 1 276 ? -42.143  -91.007  22.406  1.00 23.78  ? 276  LEU D CD2   1 
ATOM   12046 N N     . VAL D 1 277 ? -39.298  -91.766  18.625  1.00 17.39  ? 277  VAL D N     1 
ATOM   12047 C CA    . VAL D 1 277 ? -38.913  -92.384  17.368  1.00 17.93  ? 277  VAL D CA    1 
ATOM   12048 C C     . VAL D 1 277 ? -39.833  -93.587  17.172  1.00 18.63  ? 277  VAL D C     1 
ATOM   12049 O O     . VAL D 1 277 ? -39.905  -94.464  18.049  1.00 18.12  ? 277  VAL D O     1 
ATOM   12050 C CB    . VAL D 1 277 ? -37.431  -92.812  17.395  1.00 19.39  ? 277  VAL D CB    1 
ATOM   12051 C CG1   . VAL D 1 277 ? -37.011  -93.623  16.159  1.00 17.31  ? 277  VAL D CG1   1 
ATOM   12052 C CG2   . VAL D 1 277 ? -36.525  -91.608  17.586  1.00 19.01  ? 277  VAL D CG2   1 
ATOM   12053 N N     . ASN D 1 278 ? -40.515  -93.630  16.027  1.00 17.45  ? 278  ASN D N     1 
ATOM   12054 C CA    . ASN D 1 278 ? -41.580  -94.595  15.818  1.00 20.36  ? 278  ASN D CA    1 
ATOM   12055 C C     . ASN D 1 278 ? -41.091  -95.835  15.075  1.00 22.48  ? 278  ASN D C     1 
ATOM   12056 O O     . ASN D 1 278 ? -40.340  -95.747  14.111  1.00 23.53  ? 278  ASN D O     1 
ATOM   12057 C CB    . ASN D 1 278 ? -42.683  -94.001  14.954  1.00 20.05  ? 278  ASN D CB    1 
ATOM   12058 C CG    . ASN D 1 278 ? -43.749  -95.035  14.713  1.00 22.12  ? 278  ASN D CG    1 
ATOM   12059 O OD1   . ASN D 1 278 ? -44.414  -95.446  15.680  1.00 21.86  ? 278  ASN D OD1   1 
ATOM   12060 N ND2   . ASN D 1 278 ? -43.884  -95.495  13.466  1.00 19.79  ? 278  ASN D ND2   1 
ATOM   12061 N N     . ILE D 1 279 ? -41.571  -97.000  15.497  1.00 22.50  ? 279  ILE D N     1 
ATOM   12062 C CA    . ILE D 1 279 ? -41.410  -98.239  14.748  1.00 23.95  ? 279  ILE D CA    1 
ATOM   12063 C C     . ILE D 1 279 ? -42.794  -98.874  14.546  1.00 23.71  ? 279  ILE D C     1 
ATOM   12064 O O     . ILE D 1 279 ? -43.631  -98.859  15.462  1.00 24.14  ? 279  ILE D O     1 
ATOM   12065 C CB    . ILE D 1 279 ? -40.612  -99.184  15.659  1.00 28.18  ? 279  ILE D CB    1 
ATOM   12066 C CG1   . ILE D 1 279 ? -39.197  -98.770  15.890  1.00 32.37  ? 279  ILE D CG1   1 
ATOM   12067 C CG2   . ILE D 1 279 ? -40.672  -100.617 15.136  1.00 30.25  ? 279  ILE D CG2   1 
ATOM   12068 C CD1   . ILE D 1 279 ? -38.596  -99.646  16.981  1.00 46.29  ? 279  ILE D CD1   1 
ATOM   12069 N N     . GLY D 1 280 ? -43.030  -99.469  13.377  1.00 20.32  ? 280  GLY D N     1 
ATOM   12070 C CA    . GLY D 1 280 ? -44.267  -100.211 13.133  1.00 17.32  ? 280  GLY D CA    1 
ATOM   12071 C C     . GLY D 1 280 ? -43.988  -101.711 13.159  1.00 19.01  ? 280  GLY D C     1 
ATOM   12072 O O     . GLY D 1 280 ? -43.137  -102.167 12.402  1.00 21.30  ? 280  GLY D O     1 
ATOM   12073 N N     . LEU D 1 281 ? -44.682  -102.482 14.023  1.00 17.81  ? 281  LEU D N     1 
ATOM   12074 C CA    . LEU D 1 281 ? -44.437  -103.916 14.110  1.00 15.95  ? 281  LEU D CA    1 
ATOM   12075 C C     . LEU D 1 281 ? -45.057  -104.625 12.906  1.00 18.07  ? 281  LEU D C     1 
ATOM   12076 O O     . LEU D 1 281 ? -45.972  -104.084 12.255  1.00 17.70  ? 281  LEU D O     1 
ATOM   12077 C CB    . LEU D 1 281 ? -44.995  -104.468 15.426  1.00 17.23  ? 281  LEU D CB    1 
ATOM   12078 C CG    . LEU D 1 281 ? -44.517  -103.777 16.718  1.00 19.49  ? 281  LEU D CG    1 
ATOM   12079 C CD1   . LEU D 1 281 ? -45.059  -104.483 17.956  1.00 19.22  ? 281  LEU D CD1   1 
ATOM   12080 C CD2   . LEU D 1 281 ? -42.965  -103.658 16.791  1.00 16.35  ? 281  LEU D CD2   1 
ATOM   12081 N N     . THR D 1 282 ? -44.561  -105.847 12.625  1.00 17.67  ? 282  THR D N     1 
ATOM   12082 C CA    . THR D 1 282 ? -45.188  -106.747 11.660  1.00 19.62  ? 282  THR D CA    1 
ATOM   12083 C C     . THR D 1 282 ? -46.573  -107.172 12.152  1.00 21.92  ? 282  THR D C     1 
ATOM   12084 O O     . THR D 1 282 ? -46.921  -106.985 13.325  1.00 21.55  ? 282  THR D O     1 
ATOM   12085 C CB    . THR D 1 282 ? -44.316  -107.983 11.393  1.00 20.39  ? 282  THR D CB    1 
ATOM   12086 O OG1   . THR D 1 282 ? -44.386  -108.795 12.569  1.00 20.83  ? 282  THR D OG1   1 
ATOM   12087 C CG2   . THR D 1 282 ? -42.885  -107.630 11.009  1.00 15.32  ? 282  THR D CG2   1 
ATOM   12088 N N     . GLY D 1 283 ? -47.353  -107.794 11.252  1.00 22.41  ? 283  GLY D N     1 
ATOM   12089 C CA    . GLY D 1 283 ? -48.685  -108.287 11.581  1.00 19.39  ? 283  GLY D CA    1 
ATOM   12090 C C     . GLY D 1 283 ? -48.688  -109.055 12.903  1.00 21.44  ? 283  GLY D C     1 
ATOM   12091 O O     . GLY D 1 283 ? -49.533  -108.834 13.765  1.00 20.99  ? 283  GLY D O     1 
ATOM   12092 N N     . THR D 1 284 ? -47.702  -109.937 13.077  1.00 22.07  ? 284  THR D N     1 
ATOM   12093 C CA    . THR D 1 284 ? -47.646  -110.834 14.220  1.00 24.82  ? 284  THR D CA    1 
ATOM   12094 C C     . THR D 1 284 ? -46.870  -110.211 15.384  1.00 30.04  ? 284  THR D C     1 
ATOM   12095 O O     . THR D 1 284 ? -46.690  -110.880 16.401  1.00 30.89  ? 284  THR D O     1 
ATOM   12096 C CB    . THR D 1 284 ? -47.046  -112.180 13.808  1.00 26.18  ? 284  THR D CB    1 
ATOM   12097 O OG1   . THR D 1 284 ? -45.771  -111.831 13.280  1.00 29.08  ? 284  THR D OG1   1 
ATOM   12098 C CG2   . THR D 1 284 ? -47.880  -112.932 12.779  1.00 23.81  ? 284  THR D CG2   1 
ATOM   12099 N N     . GLY D 1 285 ? -46.436  -108.942 15.275  1.00 26.02  ? 285  GLY D N     1 
ATOM   12100 C CA    . GLY D 1 285 ? -45.889  -108.247 16.434  1.00 22.78  ? 285  GLY D CA    1 
ATOM   12101 C C     . GLY D 1 285 ? -44.357  -108.245 16.554  1.00 25.71  ? 285  GLY D C     1 
ATOM   12102 O O     . GLY D 1 285 ? -43.824  -107.906 17.621  1.00 24.03  ? 285  GLY D O     1 
ATOM   12103 N N     . ALA D 1 286 ? -43.616  -108.582 15.487  1.00 26.33  ? 286  ALA D N     1 
ATOM   12104 C CA    . ALA D 1 286 ? -42.151  -108.506 15.534  1.00 24.35  ? 286  ALA D CA    1 
ATOM   12105 C C     . ALA D 1 286 ? -41.659  -107.093 15.183  1.00 25.24  ? 286  ALA D C     1 
ATOM   12106 O O     . ALA D 1 286 ? -42.309  -106.360 14.428  1.00 22.90  ? 286  ALA D O     1 
ATOM   12107 C CB    . ALA D 1 286 ? -41.549  -109.526 14.584  1.00 20.28  ? 286  ALA D CB    1 
ATOM   12108 N N     . ILE D 1 287 ? -40.494  -106.731 15.732  1.00 24.48  ? 287  ILE D N     1 
ATOM   12109 C CA    . ILE D 1 287 ? -39.752  -105.569 15.274  1.00 25.38  ? 287  ILE D CA    1 
ATOM   12110 C C     . ILE D 1 287 ? -39.135  -105.900 13.922  1.00 23.59  ? 287  ILE D C     1 
ATOM   12111 O O     . ILE D 1 287 ? -38.363  -106.829 13.811  1.00 22.65  ? 287  ILE D O     1 
ATOM   12112 C CB    . ILE D 1 287 ? -38.644  -105.183 16.268  1.00 22.17  ? 287  ILE D CB    1 
ATOM   12113 C CG1   . ILE D 1 287 ? -39.252  -104.947 17.644  1.00 25.81  ? 287  ILE D CG1   1 
ATOM   12114 C CG2   . ILE D 1 287 ? -37.856  -103.959 15.749  1.00 20.31  ? 287  ILE D CG2   1 
ATOM   12115 C CD1   . ILE D 1 287 ? -38.265  -104.417 18.666  1.00 26.36  ? 287  ILE D CD1   1 
ATOM   12116 N N     . PRO D 1 288 ? -39.447  -105.175 12.841  1.00 24.92  ? 288  PRO D N     1 
ATOM   12117 C CA    . PRO D 1 288 ? -38.804  -105.465 11.559  1.00 26.90  ? 288  PRO D CA    1 
ATOM   12118 C C     . PRO D 1 288 ? -37.297  -105.189 11.572  1.00 27.36  ? 288  PRO D C     1 
ATOM   12119 O O     . PRO D 1 288 ? -36.821  -104.296 12.280  1.00 27.71  ? 288  PRO D O     1 
ATOM   12120 C CB    . PRO D 1 288 ? -39.537  -104.572 10.547  1.00 25.36  ? 288  PRO D CB    1 
ATOM   12121 C CG    . PRO D 1 288 ? -40.410  -103.651 11.380  1.00 21.53  ? 288  PRO D CG    1 
ATOM   12122 C CD    . PRO D 1 288 ? -40.354  -104.018 12.829  1.00 23.70  ? 288  PRO D CD    1 
ATOM   12123 N N     . ALA D 1 289 ? -36.562  -105.921 10.717  1.00 28.14  ? 289  ALA D N     1 
ATOM   12124 C CA    . ALA D 1 289 ? -35.108  -105.796 10.619  1.00 26.75  ? 289  ALA D CA    1 
ATOM   12125 C C     . ALA D 1 289 ? -34.697  -104.345 10.325  1.00 25.70  ? 289  ALA D C     1 
ATOM   12126 O O     . ALA D 1 289 ? -33.741  -103.843 10.913  1.00 30.63  ? 289  ALA D O     1 
ATOM   12127 C CB    . ALA D 1 289 ? -34.543  -106.790 9.598   1.00 19.81  ? 289  ALA D CB    1 
ATOM   12128 N N     . ALA D 1 290 ? -35.426  -103.645 9.438   1.00 21.97  ? 290  ALA D N     1 
ATOM   12129 C CA    . ALA D 1 290 ? -35.060  -102.281 9.095   1.00 22.74  ? 290  ALA D CA    1 
ATOM   12130 C C     . ALA D 1 290 ? -35.063  -101.387 10.336  1.00 23.57  ? 290  ALA D C     1 
ATOM   12131 O O     . ALA D 1 290 ? -34.148  -100.574 10.518  1.00 25.93  ? 290  ALA D O     1 
ATOM   12132 C CB    . ALA D 1 290 ? -35.929  -101.729 7.974   1.00 18.95  ? 290  ALA D CB    1 
ATOM   12133 N N     . ALA D 1 291 ? -36.084  -101.553 11.197  1.00 23.73  ? 291  ALA D N     1 
ATOM   12134 C CA    . ALA D 1 291 ? -36.200  -100.718 12.378  1.00 20.91  ? 291  ALA D CA    1 
ATOM   12135 C C     . ALA D 1 291 ? -35.026  -101.002 13.322  1.00 23.19  ? 291  ALA D C     1 
ATOM   12136 O O     . ALA D 1 291 ? -34.499  -100.072 13.940  1.00 21.22  ? 291  ALA D O     1 
ATOM   12137 C CB    . ALA D 1 291 ? -37.520  -100.979 13.071  1.00 20.88  ? 291  ALA D CB    1 
ATOM   12138 N N     . GLN D 1 292 ? -34.579  -102.234 13.396  1.00 21.78  ? 292  GLN D N     1 
ATOM   12139 C CA    . GLN D 1 292 ? -33.469  -102.571 14.238  1.00 24.50  ? 292  GLN D CA    1 
ATOM   12140 C C     . GLN D 1 292 ? -32.186  -101.870 13.848  1.00 24.91  ? 292  GLN D C     1 
ATOM   12141 O O     . GLN D 1 292 ? -31.441  -101.510 14.683  1.00 23.37  ? 292  GLN D O     1 
ATOM   12142 C CB    . GLN D 1 292 ? -33.236  -104.066 14.300  1.00 28.54  ? 292  GLN D CB    1 
ATOM   12143 C CG    . GLN D 1 292 ? -34.268  -104.862 15.028  1.00 37.40  ? 292  GLN D CG    1 
ATOM   12144 C CD    . GLN D 1 292 ? -34.159  -104.839 16.536  1.00 50.68  ? 292  GLN D CD    1 
ATOM   12145 O OE1   . GLN D 1 292 ? -33.546  -103.970 17.130  1.00 45.24  ? 292  GLN D OE1   1 
ATOM   12146 N NE2   . GLN D 1 292 ? -34.793  -105.800 17.160  1.00 42.28  ? 292  GLN D NE2   1 
ATOM   12147 N N     . THR D 1 293 ? -31.957  -101.709 12.562  1.00 21.55  ? 293  THR D N     1 
ATOM   12148 C CA    . THR D 1 293 ? -30.795  -101.050 12.052  1.00 20.54  ? 293  THR D CA    1 
ATOM   12149 C C     . THR D 1 293 ? -30.757  -99.594  12.503  1.00 21.27  ? 293  THR D C     1 
ATOM   12150 O O     . THR D 1 293 ? -29.763  -99.140  12.935  1.00 23.01  ? 293  THR D O     1 
ATOM   12151 C CB    . THR D 1 293 ? -30.745  -101.154 10.519  1.00 21.90  ? 293  THR D CB    1 
ATOM   12152 O OG1   . THR D 1 293 ? -30.329  -102.439 10.144  1.00 21.89  ? 293  THR D OG1   1 
ATOM   12153 C CG2   . THR D 1 293 ? -29.823  -100.181 9.925   1.00 18.08  ? 293  THR D CG2   1 
ATOM   12154 N N     . TYR D 1 294 ? -31.874  -98.913  12.437  1.00 19.37  ? 294  TYR D N     1 
ATOM   12155 C CA    . TYR D 1 294 ? -31.984  -97.545  12.871  1.00 21.78  ? 294  TYR D CA    1 
ATOM   12156 C C     . TYR D 1 294 ? -31.753  -97.416  14.373  1.00 20.71  ? 294  TYR D C     1 
ATOM   12157 O O     . TYR D 1 294 ? -31.137  -96.516  14.827  1.00 19.63  ? 294  TYR D O     1 
ATOM   12158 C CB    . TYR D 1 294 ? -33.305  -96.916  12.412  1.00 21.50  ? 294  TYR D CB    1 
ATOM   12159 C CG    . TYR D 1 294 ? -33.268  -96.457  10.998  1.00 22.13  ? 294  TYR D CG    1 
ATOM   12160 C CD1   . TYR D 1 294 ? -33.386  -97.346  9.966   1.00 20.76  ? 294  TYR D CD1   1 
ATOM   12161 C CD2   . TYR D 1 294 ? -33.089  -95.139  10.687  1.00 21.83  ? 294  TYR D CD2   1 
ATOM   12162 C CE1   . TYR D 1 294 ? -33.330  -96.933  8.677   1.00 22.75  ? 294  TYR D CE1   1 
ATOM   12163 C CE2   . TYR D 1 294 ? -33.028  -94.727  9.393   1.00 21.75  ? 294  TYR D CE2   1 
ATOM   12164 C CZ    . TYR D 1 294 ? -33.147  -95.641  8.396   1.00 23.95  ? 294  TYR D CZ    1 
ATOM   12165 O OH    . TYR D 1 294 ? -33.112  -95.260  7.121   1.00 25.37  ? 294  TYR D OH    1 
ATOM   12166 N N     . MET D 1 295 ? -32.260  -98.362  15.119  1.00 18.87  ? 295  MET D N     1 
ATOM   12167 C CA    . MET D 1 295 ? -32.084  -98.396  16.538  1.00 21.72  ? 295  MET D CA    1 
ATOM   12168 C C     . MET D 1 295 ? -30.679  -98.578  16.996  1.00 21.16  ? 295  MET D C     1 
ATOM   12169 O O     . MET D 1 295 ? -30.290  -98.031  17.958  1.00 22.94  ? 295  MET D O     1 
ATOM   12170 C CB    . MET D 1 295 ? -32.883  -99.505  17.070  1.00 25.81  ? 295  MET D CB    1 
ATOM   12171 C CG    . MET D 1 295 ? -34.228  -99.449  16.494  1.00 40.18  ? 295  MET D CG    1 
ATOM   12172 S SD    . MET D 1 295 ? -35.221  -98.682  17.712  1.00 49.09  ? 295  MET D SD    1 
ATOM   12173 C CE    . MET D 1 295 ? -35.954  -100.181 18.235  1.00 30.11  ? 295  MET D CE    1 
ATOM   12174 N N     . HIS D 1 296 ? -29.963  -99.440  16.320  1.00 19.36  ? 296  HIS D N     1 
ATOM   12175 C CA    . HIS D 1 296 ? -28.585  -99.658  16.620  1.00 23.78  ? 296  HIS D CA    1 
ATOM   12176 C C     . HIS D 1 296 ? -27.732  -98.456  16.377  1.00 23.73  ? 296  HIS D C     1 
ATOM   12177 O O     . HIS D 1 296 ? -26.876  -98.205  17.142  1.00 24.57  ? 296  HIS D O     1 
ATOM   12178 C CB    . HIS D 1 296 ? -28.026  -100.863 15.913  1.00 26.68  ? 296  HIS D CB    1 
ATOM   12179 C CG    . HIS D 1 296 ? -28.563  -102.137 16.428  1.00 38.29  ? 296  HIS D CG    1 
ATOM   12180 N ND1   . HIS D 1 296 ? -29.125  -103.077 15.615  1.00 49.28  ? 296  HIS D ND1   1 
ATOM   12181 C CD2   . HIS D 1 296 ? -28.660  -102.620 17.677  1.00 45.04  ? 296  HIS D CD2   1 
ATOM   12182 C CE1   . HIS D 1 296 ? -29.548  -104.084 16.340  1.00 44.92  ? 296  HIS D CE1   1 
ATOM   12183 N NE2   . HIS D 1 296 ? -29.264  -103.837 17.592  1.00 47.28  ? 296  HIS D NE2   1 
ATOM   12184 N N     . LEU D 1 297 ? -27.961  -97.755  15.288  1.00 19.98  ? 297  LEU D N     1 
ATOM   12185 C CA    . LEU D 1 297 ? -27.228  -96.555  14.991  1.00 21.92  ? 297  LEU D CA    1 
ATOM   12186 C C     . LEU D 1 297 ? -27.529  -95.454  15.976  1.00 23.43  ? 297  LEU D C     1 
ATOM   12187 O O     . LEU D 1 297 ? -26.647  -94.788  16.425  1.00 25.08  ? 297  LEU D O     1 
ATOM   12188 C CB    . LEU D 1 297 ? -27.452  -96.100  13.547  1.00 19.85  ? 297  LEU D CB    1 
ATOM   12189 C CG    . LEU D 1 297 ? -26.937  -97.032  12.476  1.00 20.54  ? 297  LEU D CG    1 
ATOM   12190 C CD1   . LEU D 1 297 ? -27.426  -96.780  11.090  1.00 18.45  ? 297  LEU D CD1   1 
ATOM   12191 C CD2   . LEU D 1 297 ? -25.457  -97.283  12.497  1.00 15.68  ? 297  LEU D CD2   1 
ATOM   12192 N N     . LEU D 1 298 ? -28.798  -95.304  16.310  1.00 23.93  ? 298  LEU D N     1 
ATOM   12193 C CA    . LEU D 1 298 ? -29.268  -94.320  17.249  1.00 21.57  ? 298  LEU D CA    1 
ATOM   12194 C C     . LEU D 1 298 ? -28.745  -94.604  18.634  1.00 20.83  ? 298  LEU D C     1 
ATOM   12195 O O     . LEU D 1 298 ? -28.357  -93.737  19.332  1.00 18.08  ? 298  LEU D O     1 
ATOM   12196 C CB    . LEU D 1 298 ? -30.782  -94.178  17.199  1.00 24.70  ? 298  LEU D CB    1 
ATOM   12197 C CG    . LEU D 1 298 ? -31.405  -93.126  18.097  1.00 28.77  ? 298  LEU D CG    1 
ATOM   12198 C CD1   . LEU D 1 298 ? -30.808  -91.777  17.844  1.00 25.58  ? 298  LEU D CD1   1 
ATOM   12199 C CD2   . LEU D 1 298 ? -32.900  -93.064  17.973  1.00 27.52  ? 298  LEU D CD2   1 
ATOM   12200 N N     . GLY D 1 299 ? -28.707  -95.868  18.970  1.00 19.03  ? 299  GLY D N     1 
ATOM   12201 C CA    . GLY D 1 299 ? -28.198  -96.338  20.221  1.00 18.81  ? 299  GLY D CA    1 
ATOM   12202 C C     . GLY D 1 299 ? -26.750  -96.002  20.399  1.00 20.13  ? 299  GLY D C     1 
ATOM   12203 O O     . GLY D 1 299 ? -26.355  -95.729  21.459  1.00 20.43  ? 299  GLY D O     1 
ATOM   12204 N N     . ARG D 1 300 ? -25.952  -96.082  19.364  1.00 18.85  ? 300  ARG D N     1 
ATOM   12205 C CA    . ARG D 1 300 ? -24.585  -95.682  19.477  1.00 18.69  ? 300  ARG D CA    1 
ATOM   12206 C C     . ARG D 1 300 ? -24.488  -94.213  19.766  1.00 20.18  ? 300  ARG D C     1 
ATOM   12207 O O     . ARG D 1 300 ? -23.704  -93.824  20.558  1.00 21.72  ? 300  ARG D O     1 
ATOM   12208 C CB    . ARG D 1 300 ? -23.808  -95.998  18.234  1.00 20.21  ? 300  ARG D CB    1 
ATOM   12209 C CG    . ARG D 1 300 ? -23.477  -97.429  18.056  1.00 19.80  ? 300  ARG D CG    1 
ATOM   12210 C CD    . ARG D 1 300 ? -22.909  -97.632  16.701  1.00 25.05  ? 300  ARG D CD    1 
ATOM   12211 N NE    . ARG D 1 300 ? -22.691  -99.022  16.439  1.00 35.07  ? 300  ARG D NE    1 
ATOM   12212 C CZ    . ARG D 1 300 ? -21.647  -99.719  16.827  1.00 34.91  ? 300  ARG D CZ    1 
ATOM   12213 N NH1   . ARG D 1 300 ? -20.667  -99.171  17.473  1.00 31.55  ? 300  ARG D NH1   1 
ATOM   12214 N NH2   . ARG D 1 300 ? -21.584  -100.970 16.520  1.00 35.19  ? 300  ARG D NH2   1 
ATOM   12215 N N     . TRP D 1 301 ? -25.307  -93.405  19.125  1.00 17.65  ? 301  TRP D N     1 
ATOM   12216 C CA    . TRP D 1 301 ? -25.246  -91.977  19.382  1.00 18.55  ? 301  TRP D CA    1 
ATOM   12217 C C     . TRP D 1 301 ? -25.729  -91.646  20.805  1.00 21.12  ? 301  TRP D C     1 
ATOM   12218 O O     . TRP D 1 301 ? -25.108  -90.828  21.492  1.00 20.48  ? 301  TRP D O     1 
ATOM   12219 C CB    . TRP D 1 301 ? -26.040  -91.194  18.324  1.00 17.00  ? 301  TRP D CB    1 
ATOM   12220 C CG    . TRP D 1 301 ? -25.854  -89.704  18.461  1.00 16.50  ? 301  TRP D CG    1 
ATOM   12221 C CD1   . TRP D 1 301 ? -24.842  -88.974  17.912  1.00 15.97  ? 301  TRP D CD1   1 
ATOM   12222 C CD2   . TRP D 1 301 ? -26.674  -88.777  19.210  1.00 15.85  ? 301  TRP D CD2   1 
ATOM   12223 N NE1   . TRP D 1 301 ? -24.982  -87.658  18.260  1.00 19.60  ? 301  TRP D NE1   1 
ATOM   12224 C CE2   . TRP D 1 301 ? -26.094  -87.499  19.051  1.00 16.97  ? 301  TRP D CE2   1 
ATOM   12225 C CE3   . TRP D 1 301 ? -27.836  -88.895  19.985  1.00 14.85  ? 301  TRP D CE3   1 
ATOM   12226 C CZ2   . TRP D 1 301 ? -26.621  -86.348  19.653  1.00 16.43  ? 301  TRP D CZ2   1 
ATOM   12227 C CZ3   . TRP D 1 301 ? -28.367  -87.760  20.569  1.00 14.79  ? 301  TRP D CZ3   1 
ATOM   12228 C CH2   . TRP D 1 301 ? -27.767  -86.502  20.409  1.00 16.06  ? 301  TRP D CH2   1 
ATOM   12229 N N     . THR D 1 302 ? -26.850  -92.247  21.245  1.00 20.51  ? 302  THR D N     1 
ATOM   12230 C CA    . THR D 1 302 ? -27.420  -91.826  22.517  1.00 19.81  ? 302  THR D CA    1 
ATOM   12231 C C     . THR D 1 302 ? -26.523  -92.308  23.653  1.00 20.43  ? 302  THR D C     1 
ATOM   12232 O O     . THR D 1 302 ? -26.438  -91.642  24.674  1.00 21.05  ? 302  THR D O     1 
ATOM   12233 C CB    . THR D 1 302 ? -28.871  -92.289  22.689  1.00 18.66  ? 302  THR D CB    1 
ATOM   12234 O OG1   . THR D 1 302 ? -28.816  -93.711  22.685  1.00 22.08  ? 302  THR D OG1   1 
ATOM   12235 C CG2   . THR D 1 302 ? -29.817  -91.764  21.626  1.00 14.15  ? 302  THR D CG2   1 
ATOM   12236 N N     . ALA D 1 303 ? -25.830  -93.444  23.487  1.00 20.46  ? 303  ALA D N     1 
ATOM   12237 C CA    . ALA D 1 303 ? -24.871  -93.880  24.511  1.00 20.90  ? 303  ALA D CA    1 
ATOM   12238 C C     . ALA D 1 303 ? -23.763  -92.832  24.663  1.00 21.40  ? 303  ALA D C     1 
ATOM   12239 O O     . ALA D 1 303 ? -23.410  -92.479  25.774  1.00 21.92  ? 303  ALA D O     1 
ATOM   12240 C CB    . ALA D 1 303 ? -24.318  -95.282  24.244  1.00 15.57  ? 303  ALA D CB    1 
ATOM   12241 N N     . MET D 1 304 ? -23.245  -92.310  23.544  1.00 20.59  ? 304  MET D N     1 
ATOM   12242 C CA    . MET D 1 304 ? -22.228  -91.269  23.584  1.00 20.01  ? 304  MET D CA    1 
ATOM   12243 C C     . MET D 1 304 ? -22.803  -90.001  24.230  1.00 21.24  ? 304  MET D C     1 
ATOM   12244 O O     . MET D 1 304 ? -22.123  -89.347  25.016  1.00 22.98  ? 304  MET D O     1 
ATOM   12245 C CB    . MET D 1 304 ? -21.656  -91.040  22.173  1.00 18.99  ? 304  MET D CB    1 
ATOM   12246 C CG    . MET D 1 304 ? -20.703  -89.840  21.996  1.00 18.28  ? 304  MET D CG    1 
ATOM   12247 S SD    . MET D 1 304 ? -21.499  -88.213  21.944  1.00 21.96  ? 304  MET D SD    1 
ATOM   12248 C CE    . MET D 1 304 ? -22.418  -88.272  20.389  1.00 17.68  ? 304  MET D CE    1 
ATOM   12249 N N     . ALA D 1 305 ? -24.059  -89.666  23.929  1.00 20.87  ? 305  ALA D N     1 
ATOM   12250 C CA    . ALA D 1 305 ? -24.656  -88.392  24.337  1.00 22.25  ? 305  ALA D CA    1 
ATOM   12251 C C     . ALA D 1 305 ? -25.265  -88.434  25.738  1.00 20.19  ? 305  ALA D C     1 
ATOM   12252 O O     . ALA D 1 305 ? -25.765  -87.402  26.189  1.00 21.76  ? 305  ALA D O     1 
ATOM   12253 C CB    . ALA D 1 305 ? -25.730  -87.941  23.321  1.00 18.46  ? 305  ALA D CB    1 
ATOM   12254 N N     . ALA D 1 306 ? -25.241  -89.597  26.400  1.00 21.29  ? 306  ALA D N     1 
ATOM   12255 C CA    . ALA D 1 306 ? -25.863  -89.819  27.715  1.00 24.42  ? 306  ALA D CA    1 
ATOM   12256 C C     . ALA D 1 306 ? -25.621  -88.698  28.734  1.00 23.30  ? 306  ALA D C     1 
ATOM   12257 O O     . ALA D 1 306 ? -26.544  -88.340  29.477  1.00 24.26  ? 306  ALA D O     1 
ATOM   12258 C CB    . ALA D 1 306 ? -25.485  -91.182  28.301  1.00 22.12  ? 306  ALA D CB    1 
ATOM   12259 N N     . PRO D 1 307 ? -24.406  -88.114  28.879  1.00 23.71  ? 307  PRO D N     1 
ATOM   12260 C CA    . PRO D 1 307 ? -24.228  -87.053  29.878  1.00 21.03  ? 307  PRO D CA    1 
ATOM   12261 C C     . PRO D 1 307 ? -25.127  -85.838  29.663  1.00 22.11  ? 307  PRO D C     1 
ATOM   12262 O O     . PRO D 1 307 ? -25.319  -85.105  30.620  1.00 22.52  ? 307  PRO D O     1 
ATOM   12263 C CB    . PRO D 1 307 ? -22.735  -86.646  29.779  1.00 19.67  ? 307  PRO D CB    1 
ATOM   12264 C CG    . PRO D 1 307 ? -22.110  -87.883  29.139  1.00 21.09  ? 307  PRO D CG    1 
ATOM   12265 C CD    . PRO D 1 307 ? -23.153  -88.467  28.191  1.00 19.13  ? 307  PRO D CD    1 
ATOM   12266 N N     . VAL D 1 308 ? -25.687  -85.629  28.444  1.00 21.47  ? 308  VAL D N     1 
ATOM   12267 C CA    . VAL D 1 308 ? -26.468  -84.420  28.223  1.00 21.72  ? 308  VAL D CA    1 
ATOM   12268 C C     . VAL D 1 308 ? -27.888  -84.733  27.740  1.00 19.77  ? 308  VAL D C     1 
ATOM   12269 O O     . VAL D 1 308 ? -28.779  -83.892  27.864  1.00 19.20  ? 308  VAL D O     1 
ATOM   12270 C CB    . VAL D 1 308 ? -25.749  -83.425  27.270  1.00 24.03  ? 308  VAL D CB    1 
ATOM   12271 C CG1   . VAL D 1 308 ? -25.630  -83.968  25.830  1.00 19.98  ? 308  VAL D CG1   1 
ATOM   12272 C CG2   . VAL D 1 308 ? -26.466  -82.086  27.235  1.00 17.50  ? 308  VAL D CG2   1 
ATOM   12273 N N     . LEU D 1 309 ? -28.112  -85.903  27.133  1.00 18.84  ? 309  LEU D N     1 
ATOM   12274 C CA    . LEU D 1 309 ? -29.375  -86.153  26.454  1.00 19.58  ? 309  LEU D CA    1 
ATOM   12275 C C     . LEU D 1 309 ? -30.569  -86.017  27.410  1.00 20.21  ? 309  LEU D C     1 
ATOM   12276 O O     . LEU D 1 309 ? -31.618  -85.541  26.979  1.00 20.32  ? 309  LEU D O     1 
ATOM   12277 C CB    . LEU D 1 309 ? -29.338  -87.540  25.817  1.00 20.74  ? 309  LEU D CB    1 
ATOM   12278 C CG    . LEU D 1 309 ? -30.625  -87.994  25.113  1.00 22.49  ? 309  LEU D CG    1 
ATOM   12279 C CD1   . LEU D 1 309 ? -30.938  -87.101  23.934  1.00 20.55  ? 309  LEU D CD1   1 
ATOM   12280 C CD2   . LEU D 1 309 ? -30.446  -89.446  24.657  1.00 22.03  ? 309  LEU D CD2   1 
ATOM   12281 N N     . TYR D 1 310 ? -30.436  -86.475  28.673  1.00 17.91  ? 310  TYR D N     1 
ATOM   12282 C CA    . TYR D 1 310 ? -31.540  -86.511  29.630  1.00 19.03  ? 310  TYR D CA    1 
ATOM   12283 C C     . TYR D 1 310 ? -31.696  -85.184  30.392  1.00 22.07  ? 310  TYR D C     1 
ATOM   12284 O O     . TYR D 1 310 ? -32.787  -84.618  30.411  1.00 22.05  ? 310  TYR D O     1 
ATOM   12285 C CB    . TYR D 1 310 ? -31.412  -87.734  30.547  1.00 19.72  ? 310  TYR D CB    1 
ATOM   12286 C CG    . TYR D 1 310 ? -31.255  -88.975  29.686  1.00 20.52  ? 310  TYR D CG    1 
ATOM   12287 C CD1   . TYR D 1 310 ? -32.310  -89.426  28.897  1.00 20.39  ? 310  TYR D CD1   1 
ATOM   12288 C CD2   . TYR D 1 310 ? -30.021  -89.630  29.582  1.00 20.92  ? 310  TYR D CD2   1 
ATOM   12289 C CE1   . TYR D 1 310 ? -32.147  -90.512  28.045  1.00 20.18  ? 310  TYR D CE1   1 
ATOM   12290 C CE2   . TYR D 1 310 ? -29.844  -90.731  28.752  1.00 19.36  ? 310  TYR D CE2   1 
ATOM   12291 C CZ    . TYR D 1 310 ? -30.913  -91.174  27.984  1.00 21.58  ? 310  TYR D CZ    1 
ATOM   12292 O OH    . TYR D 1 310 ? -30.745  -92.247  27.133  1.00 21.75  ? 310  TYR D OH    1 
ATOM   12293 N N     . LYS D 1 311 ? -30.605  -84.649  30.961  1.00 22.21  ? 311  LYS D N     1 
ATOM   12294 C CA    . LYS D 1 311 ? -30.692  -83.478  31.823  1.00 22.32  ? 311  LYS D CA    1 
ATOM   12295 C C     . LYS D 1 311 ? -30.456  -82.166  31.065  1.00 23.80  ? 311  LYS D C     1 
ATOM   12296 O O     . LYS D 1 311 ? -30.729  -81.094  31.619  1.00 21.30  ? 311  LYS D O     1 
ATOM   12297 C CB    . LYS D 1 311 ? -29.625  -83.565  32.916  1.00 25.15  ? 311  LYS D CB    1 
ATOM   12298 C CG    . LYS D 1 311 ? -29.747  -84.794  33.805  1.00 28.81  ? 311  LYS D CG    1 
ATOM   12299 C CD    . LYS D 1 311 ? -30.930  -84.574  34.739  1.00 33.51  ? 311  LYS D CD    1 
ATOM   12300 C CE    . LYS D 1 311 ? -31.073  -85.696  35.751  1.00 40.46  ? 311  LYS D CE    1 
ATOM   12301 N NZ    . LYS D 1 311 ? -32.168  -85.306  36.642  1.00 35.17  ? 311  LYS D NZ    1 
ATOM   12302 N N     . GLY D 1 312 ? -29.933  -82.215  29.820  1.00 19.65  ? 312  GLY D N     1 
ATOM   12303 C CA    . GLY D 1 312 ? -29.616  -80.977  29.115  1.00 19.07  ? 312  GLY D CA    1 
ATOM   12304 C C     . GLY D 1 312 ? -30.874  -80.169  28.783  1.00 22.06  ? 312  GLY D C     1 
ATOM   12305 O O     . GLY D 1 312 ? -31.905  -80.731  28.395  1.00 21.77  ? 312  GLY D O     1 
ATOM   12306 N N     . ARG D 1 313 ? -30.778  -78.841  28.908  1.00 20.00  ? 313  ARG D N     1 
ATOM   12307 C CA    . ARG D 1 313 ? -31.911  -77.969  28.647  1.00 19.90  ? 313  ARG D CA    1 
ATOM   12308 C C     . ARG D 1 313 ? -31.449  -76.800  27.787  1.00 20.76  ? 313  ARG D C     1 
ATOM   12309 O O     . ARG D 1 313 ? -30.286  -76.406  27.828  1.00 21.39  ? 313  ARG D O     1 
ATOM   12310 C CB    . ARG D 1 313 ? -32.490  -77.406  29.958  1.00 19.24  ? 313  ARG D CB    1 
ATOM   12311 C CG    . ARG D 1 313 ? -33.114  -78.443  30.876  1.00 16.44  ? 313  ARG D CG    1 
ATOM   12312 C CD    . ARG D 1 313 ? -34.376  -79.052  30.217  1.00 18.37  ? 313  ARG D CD    1 
ATOM   12313 N NE    . ARG D 1 313 ? -34.999  -80.058  31.095  1.00 19.22  ? 313  ARG D NE    1 
ATOM   12314 C CZ    . ARG D 1 313 ? -34.618  -81.337  31.260  1.00 20.33  ? 313  ARG D CZ    1 
ATOM   12315 N NH1   . ARG D 1 313 ? -33.736  -81.886  30.457  1.00 21.08  ? 313  ARG D NH1   1 
ATOM   12316 N NH2   . ARG D 1 313 ? -35.211  -82.096  32.154  1.00 21.46  ? 313  ARG D NH2   1 
ATOM   12317 N N     . PRO D 1 314 ? -32.359  -76.194  26.990  1.00 23.05  ? 314  PRO D N     1 
ATOM   12318 C CA    . PRO D 1 314 ? -31.994  -75.011  26.208  1.00 24.84  ? 314  PRO D CA    1 
ATOM   12319 C C     . PRO D 1 314 ? -31.536  -73.876  27.122  1.00 27.65  ? 314  PRO D C     1 
ATOM   12320 O O     . PRO D 1 314 ? -31.922  -73.805  28.280  1.00 27.01  ? 314  PRO D O     1 
ATOM   12321 C CB    . PRO D 1 314 ? -33.298  -74.587  25.552  1.00 21.21  ? 314  PRO D CB    1 
ATOM   12322 C CG    . PRO D 1 314 ? -34.194  -75.810  25.663  1.00 19.98  ? 314  PRO D CG    1 
ATOM   12323 C CD    . PRO D 1 314 ? -33.776  -76.579  26.866  1.00 18.32  ? 314  PRO D CD    1 
ATOM   12324 N N     . VAL D 1 315 ? -30.726  -72.978  26.588  1.00 27.92  ? 315  VAL D N     1 
ATOM   12325 C CA    . VAL D 1 315 ? -30.175  -71.895  27.380  1.00 31.47  ? 315  VAL D CA    1 
ATOM   12326 C C     . VAL D 1 315 ? -29.975  -70.729  26.416  1.00 30.05  ? 315  VAL D C     1 
ATOM   12327 O O     . VAL D 1 315 ? -29.834  -70.976  25.233  1.00 26.90  ? 315  VAL D O     1 
ATOM   12328 C CB    . VAL D 1 315 ? -28.873  -72.483  27.977  1.00 30.35  ? 315  VAL D CB    1 
ATOM   12329 C CG1   . VAL D 1 315 ? -27.782  -72.732  26.958  1.00 26.02  ? 315  VAL D CG1   1 
ATOM   12330 C CG2   . VAL D 1 315 ? -28.369  -71.722  29.185  1.00 32.63  ? 315  VAL D CG2   1 
ATOM   12331 N N     . PRO D 1 316 ? -30.072  -69.450  26.832  1.00 30.73  ? 316  PRO D N     1 
ATOM   12332 C CA    . PRO D 1 316 ? -29.964  -68.341  25.878  1.00 34.88  ? 316  PRO D CA    1 
ATOM   12333 C C     . PRO D 1 316 ? -28.520  -68.104  25.387  1.00 35.51  ? 316  PRO D C     1 
ATOM   12334 O O     . PRO D 1 316 ? -27.858  -67.140  25.759  1.00 36.33  ? 316  PRO D O     1 
ATOM   12335 C CB    . PRO D 1 316 ? -30.601  -67.172  26.668  1.00 31.69  ? 316  PRO D CB    1 
ATOM   12336 C CG    . PRO D 1 316 ? -30.169  -67.484  28.115  1.00 32.63  ? 316  PRO D CG    1 
ATOM   12337 C CD    . PRO D 1 316 ? -30.261  -68.997  28.225  1.00 29.78  ? 316  PRO D CD    1 
ATOM   12338 N N     . VAL D 1 317 ? -27.980  -69.065  24.636  1.00 33.35  ? 317  VAL D N     1 
ATOM   12339 C CA    . VAL D 1 317 ? -26.639  -68.998  24.094  1.00 29.67  ? 317  VAL D CA    1 
ATOM   12340 C C     . VAL D 1 317 ? -26.812  -69.308  22.620  1.00 34.14  ? 317  VAL D C     1 
ATOM   12341 O O     . VAL D 1 317 ? -27.365  -70.357  22.289  1.00 34.54  ? 317  VAL D O     1 
ATOM   12342 C CB    . VAL D 1 317 ? -25.659  -70.002  24.727  1.00 31.37  ? 317  VAL D CB    1 
ATOM   12343 C CG1   . VAL D 1 317 ? -24.289  -69.961  24.045  1.00 28.27  ? 317  VAL D CG1   1 
ATOM   12344 C CG2   . VAL D 1 317 ? -25.511  -69.774  26.229  1.00 26.08  ? 317  VAL D CG2   1 
ATOM   12345 N N     . THR D 1 318 ? -26.404  -68.386  21.747  1.00 30.06  ? 318  THR D N     1 
ATOM   12346 C CA    . THR D 1 318 ? -26.598  -68.656  20.329  1.00 30.79  ? 318  THR D CA    1 
ATOM   12347 C C     . THR D 1 318 ? -25.257  -68.985  19.658  1.00 30.02  ? 318  THR D C     1 
ATOM   12348 O O     . THR D 1 318 ? -24.176  -68.729  20.187  1.00 34.67  ? 318  THR D O     1 
ATOM   12349 C CB    . THR D 1 318 ? -27.332  -67.495  19.657  1.00 31.65  ? 318  THR D CB    1 
ATOM   12350 O OG1   . THR D 1 318 ? -26.478  -66.356  19.778  1.00 33.04  ? 318  THR D OG1   1 
ATOM   12351 C CG2   . THR D 1 318 ? -28.711  -67.249  20.252  1.00 29.11  ? 318  THR D CG2   1 
ATOM   12352 N N     . SER D 1 319 ? -25.336  -69.548  18.462  1.00 24.14  ? 319  SER D N     1 
ATOM   12353 C CA    . SER D 1 319 ? -24.151  -69.866  17.705  1.00 25.38  ? 319  SER D CA    1 
ATOM   12354 C C     . SER D 1 319 ? -23.891  -68.758  16.684  1.00 27.00  ? 319  SER D C     1 
ATOM   12355 O O     . SER D 1 319 ? -24.785  -67.985  16.357  1.00 29.09  ? 319  SER D O     1 
ATOM   12356 C CB    . SER D 1 319 ? -24.304  -71.229  17.065  1.00 26.25  ? 319  SER D CB    1 
ATOM   12357 O OG    . SER D 1 319 ? -25.235  -71.187  15.983  1.00 28.06  ? 319  SER D OG    1 
ATOM   12358 N N     . ALA D 1 320 ? -22.665  -68.685  16.180  1.00 26.71  ? 320  ALA D N     1 
ATOM   12359 C CA    . ALA D 1 320 ? -22.275  -67.711  15.172  1.00 27.56  ? 320  ALA D CA    1 
ATOM   12360 C C     . ALA D 1 320 ? -23.096  -67.851  13.886  1.00 27.74  ? 320  ALA D C     1 
ATOM   12361 O O     . ALA D 1 320 ? -23.617  -68.921  13.580  1.00 30.86  ? 320  ALA D O     1 
ATOM   12362 C CB    . ALA D 1 320 ? -20.792  -67.941  14.862  1.00 27.28  ? 320  ALA D CB    1 
ATOM   12363 N N     . HIS D 1 321 ? -23.092  -66.776  13.088  1.00 24.70  ? 321  HIS D N     1 
ATOM   12364 C CA    . HIS D 1 321 ? -23.691  -66.707  11.768  1.00 23.42  ? 321  HIS D CA    1 
ATOM   12365 C C     . HIS D 1 321 ? -23.262  -67.910  10.923  1.00 27.99  ? 321  HIS D C     1 
ATOM   12366 O O     . HIS D 1 321 ? -22.072  -68.223  10.809  1.00 28.16  ? 321  HIS D O     1 
ATOM   12367 C CB    . HIS D 1 321 ? -23.320  -65.373  11.113  1.00 23.95  ? 321  HIS D CB    1 
ATOM   12368 C CG    . HIS D 1 321 ? -23.761  -65.277  9.696   1.00 29.16  ? 321  HIS D CG    1 
ATOM   12369 N ND1   . HIS D 1 321 ? -25.026  -64.859  9.329   1.00 32.21  ? 321  HIS D ND1   1 
ATOM   12370 C CD2   . HIS D 1 321 ? -23.125  -65.604  8.552   1.00 26.68  ? 321  HIS D CD2   1 
ATOM   12371 C CE1   . HIS D 1 321 ? -25.155  -64.957  8.008   1.00 29.09  ? 321  HIS D CE1   1 
ATOM   12372 N NE2   . HIS D 1 321 ? -24.013  -65.422  7.526   1.00 30.82  ? 321  HIS D NE2   1 
ATOM   12373 N N     . GLY D 1 322 ? -24.257  -68.580  10.328  1.00 31.03  ? 322  GLY D N     1 
ATOM   12374 C CA    . GLY D 1 322 ? -24.001  -69.597  9.311   1.00 33.89  ? 322  GLY D CA    1 
ATOM   12375 C C     . GLY D 1 322 ? -23.725  -71.000  9.853   1.00 35.06  ? 322  GLY D C     1 
ATOM   12376 O O     . GLY D 1 322 ? -23.281  -71.846  9.088   1.00 44.15  ? 322  GLY D O     1 
ATOM   12377 N N     . THR D 1 323 ? -23.935  -71.247  11.157  1.00 29.45  ? 323  THR D N     1 
ATOM   12378 C CA    . THR D 1 323 ? -23.765  -72.587  11.691  1.00 28.05  ? 323  THR D CA    1 
ATOM   12379 C C     . THR D 1 323 ? -25.096  -73.014  12.280  1.00 27.31  ? 323  THR D C     1 
ATOM   12380 O O     . THR D 1 323 ? -25.938  -72.170  12.542  1.00 26.67  ? 323  THR D O     1 
ATOM   12381 C CB    . THR D 1 323 ? -22.620  -72.678  12.717  1.00 27.16  ? 323  THR D CB    1 
ATOM   12382 O OG1   . THR D 1 323 ? -23.104  -72.205  13.961  1.00 27.65  ? 323  THR D OG1   1 
ATOM   12383 C CG2   . THR D 1 323 ? -21.375  -71.905  12.317  1.00 21.26  ? 323  THR D CG2   1 
ATOM   12384 N N     . ARG D 1 324 ? -25.260  -74.320  12.500  1.00 29.34  ? 324  ARG D N     1 
ATOM   12385 C CA    . ARG D 1 324 ? -26.465  -74.855  13.113  1.00 25.45  ? 324  ARG D CA    1 
ATOM   12386 C C     . ARG D 1 324 ? -26.117  -75.377  14.508  1.00 27.70  ? 324  ARG D C     1 
ATOM   12387 O O     . ARG D 1 324 ? -26.911  -76.126  15.093  1.00 23.05  ? 324  ARG D O     1 
ATOM   12388 C CB    . ARG D 1 324 ? -26.955  -76.041  12.270  1.00 25.13  ? 324  ARG D CB    1 
ATOM   12389 C CG    . ARG D 1 324 ? -27.251  -75.684  10.820  1.00 25.91  ? 324  ARG D CG    1 
ATOM   12390 C CD    . ARG D 1 324 ? -27.896  -76.785  10.007  1.00 28.85  ? 324  ARG D CD    1 
ATOM   12391 N NE    . ARG D 1 324 ? -27.023  -77.950  9.795   1.00 30.70  ? 324  ARG D NE    1 
ATOM   12392 C CZ    . ARG D 1 324 ? -27.411  -79.228  9.815   1.00 27.18  ? 324  ARG D CZ    1 
ATOM   12393 N NH1   . ARG D 1 324 ? -28.646  -79.545  10.170  1.00 22.93  ? 324  ARG D NH1   1 
ATOM   12394 N NH2   . ARG D 1 324 ? -26.553  -80.193  9.500   1.00 24.55  ? 324  ARG D NH2   1 
ATOM   12395 N N     . ASP D 1 325 ? -24.949  -74.970  15.046  1.00 20.93  ? 325  ASP D N     1 
ATOM   12396 C CA    . ASP D 1 325 ? -24.513  -75.436  16.352  1.00 20.99  ? 325  ASP D CA    1 
ATOM   12397 C C     . ASP D 1 325 ? -25.442  -74.887  17.439  1.00 22.70  ? 325  ASP D C     1 
ATOM   12398 O O     . ASP D 1 325 ? -26.084  -73.861  17.236  1.00 21.85  ? 325  ASP D O     1 
ATOM   12399 C CB    . ASP D 1 325 ? -23.056  -75.029  16.552  1.00 23.50  ? 325  ASP D CB    1 
ATOM   12400 C CG    . ASP D 1 325 ? -22.102  -75.488  15.447  1.00 27.18  ? 325  ASP D CG    1 
ATOM   12401 O OD1   . ASP D 1 325 ? -22.429  -76.484  14.710  1.00 25.69  ? 325  ASP D OD1   1 
ATOM   12402 O OD2   . ASP D 1 325 ? -21.040  -74.845  15.306  1.00 27.17  ? 325  ASP D OD2   1 
ATOM   12403 N N     . PHE D 1 326 ? -25.501  -75.538  18.606  1.00 20.28  ? 326  PHE D N     1 
ATOM   12404 C CA    . PHE D 1 326 ? -26.303  -75.010  19.713  1.00 20.73  ? 326  PHE D CA    1 
ATOM   12405 C C     . PHE D 1 326 ? -25.724  -75.505  21.042  1.00 20.69  ? 326  PHE D C     1 
ATOM   12406 O O     . PHE D 1 326 ? -24.818  -76.370  21.055  1.00 19.87  ? 326  PHE D O     1 
ATOM   12407 C CB    . PHE D 1 326 ? -27.777  -75.410  19.563  1.00 18.52  ? 326  PHE D CB    1 
ATOM   12408 C CG    . PHE D 1 326 ? -28.037  -76.914  19.566  1.00 19.49  ? 326  PHE D CG    1 
ATOM   12409 C CD1   . PHE D 1 326 ? -28.283  -77.597  20.763  1.00 17.71  ? 326  PHE D CD1   1 
ATOM   12410 C CD2   . PHE D 1 326 ? -28.054  -77.653  18.370  1.00 18.82  ? 326  PHE D CD2   1 
ATOM   12411 C CE1   . PHE D 1 326 ? -28.541  -78.974  20.751  1.00 18.89  ? 326  PHE D CE1   1 
ATOM   12412 C CE2   . PHE D 1 326 ? -28.303  -79.025  18.367  1.00 18.34  ? 326  PHE D CE2   1 
ATOM   12413 C CZ    . PHE D 1 326 ? -28.550  -79.695  19.563  1.00 18.45  ? 326  PHE D CZ    1 
ATOM   12414 N N     . VAL D 1 327 ? -26.283  -75.012  22.157  1.00 19.41  ? 327  VAL D N     1 
ATOM   12415 C CA    . VAL D 1 327 ? -25.763  -75.338  23.487  1.00 20.51  ? 327  VAL D CA    1 
ATOM   12416 C C     . VAL D 1 327 ? -26.866  -75.935  24.364  1.00 22.52  ? 327  VAL D C     1 
ATOM   12417 O O     . VAL D 1 327 ? -28.008  -75.489  24.317  1.00 25.19  ? 327  VAL D O     1 
ATOM   12418 C CB    . VAL D 1 327 ? -25.216  -74.033  24.107  1.00 19.96  ? 327  VAL D CB    1 
ATOM   12419 C CG1   . VAL D 1 327 ? -24.609  -74.264  25.478  1.00 20.16  ? 327  VAL D CG1   1 
ATOM   12420 C CG2   . VAL D 1 327 ? -24.195  -73.392  23.182  1.00 21.34  ? 327  VAL D CG2   1 
ATOM   12421 N N     . LEU D 1 328 ? -26.515  -76.923  25.182  1.00 24.14  ? 328  LEU D N     1 
ATOM   12422 C CA    . LEU D 1 328 ? -27.417  -77.460  26.200  1.00 23.60  ? 328  LEU D CA    1 
ATOM   12423 C C     . LEU D 1 328 ? -26.765  -77.292  27.575  1.00 26.15  ? 328  LEU D C     1 
ATOM   12424 O O     . LEU D 1 328 ? -25.550  -77.455  27.738  1.00 26.90  ? 328  LEU D O     1 
ATOM   12425 C CB    . LEU D 1 328 ? -27.726  -78.936  25.916  1.00 21.77  ? 328  LEU D CB    1 
ATOM   12426 C CG    . LEU D 1 328 ? -28.561  -79.213  24.652  1.00 21.98  ? 328  LEU D CG    1 
ATOM   12427 C CD1   . LEU D 1 328 ? -28.615  -80.724  24.320  1.00 21.04  ? 328  LEU D CD1   1 
ATOM   12428 C CD2   . LEU D 1 328 ? -29.949  -78.591  24.789  1.00 16.71  ? 328  LEU D CD2   1 
ATOM   12429 N N     . HIS D 1 329 ? -27.593  -76.980  28.569  1.00 24.54  ? 329  HIS D N     1 
ATOM   12430 C CA    . HIS D 1 329 ? -27.146  -76.688  29.925  1.00 24.76  ? 329  HIS D CA    1 
ATOM   12431 C C     . HIS D 1 329 ? -27.598  -77.794  30.877  1.00 26.36  ? 329  HIS D C     1 
ATOM   12432 O O     . HIS D 1 329 ? -28.756  -78.212  30.834  1.00 25.63  ? 329  HIS D O     1 
ATOM   12433 C CB    . HIS D 1 329 ? -27.721  -75.320  30.318  1.00 27.91  ? 329  HIS D CB    1 
ATOM   12434 C CG    . HIS D 1 329 ? -27.499  -74.953  31.740  1.00 31.03  ? 329  HIS D CG    1 
ATOM   12435 N ND1   . HIS D 1 329 ? -26.299  -74.442  32.189  1.00 33.16  ? 329  HIS D ND1   1 
ATOM   12436 C CD2   . HIS D 1 329 ? -28.321  -75.023  32.809  1.00 31.94  ? 329  HIS D CD2   1 
ATOM   12437 C CE1   . HIS D 1 329 ? -26.394  -74.216  33.498  1.00 33.86  ? 329  HIS D CE1   1 
ATOM   12438 N NE2   . HIS D 1 329 ? -27.610  -74.561  33.893  1.00 34.61  ? 329  HIS D NE2   1 
ATOM   12439 N N     . THR D 1 330 ? -26.669  -78.310  31.686  1.00 24.49  ? 330  THR D N     1 
ATOM   12440 C CA    . THR D 1 330 ? -27.044  -79.040  32.886  1.00 27.34  ? 330  THR D CA    1 
ATOM   12441 C C     . THR D 1 330 ? -26.558  -78.232  34.083  1.00 33.21  ? 330  THR D C     1 
ATOM   12442 O O     . THR D 1 330 ? -25.943  -77.179  33.908  1.00 30.96  ? 330  THR D O     1 
ATOM   12443 C CB    . THR D 1 330 ? -26.488  -80.459  32.901  1.00 26.83  ? 330  THR D CB    1 
ATOM   12444 O OG1   . THR D 1 330 ? -25.082  -80.309  33.080  1.00 29.11  ? 330  THR D OG1   1 
ATOM   12445 C CG2   . THR D 1 330 ? -26.864  -81.255  31.663  1.00 21.53  ? 330  THR D CG2   1 
ATOM   12446 N N     . SER D 1 331 ? -26.845  -78.689  35.309  1.00 38.44  ? 331  SER D N     1 
ATOM   12447 C CA    . SER D 1 331 ? -26.475  -77.821  36.427  1.00 44.76  ? 331  SER D CA    1 
ATOM   12448 C C     . SER D 1 331 ? -24.956  -77.787  36.625  1.00 43.64  ? 331  SER D C     1 
ATOM   12449 O O     . SER D 1 331 ? -24.454  -76.797  37.128  1.00 43.03  ? 331  SER D O     1 
ATOM   12450 C CB    . SER D 1 331 ? -27.211  -78.117  37.705  1.00 38.83  ? 331  SER D CB    1 
ATOM   12451 O OG    . SER D 1 331 ? -26.884  -79.453  38.029  1.00 41.76  ? 331  SER D OG    1 
ATOM   12452 N N     . LYS D 1 332 ? -24.231  -78.812  36.165  1.00 41.63  ? 332  LYS D N     1 
ATOM   12453 C CA    . LYS D 1 332 ? -22.781  -78.865  36.313  1.00 46.71  ? 332  LYS D CA    1 
ATOM   12454 C C     . LYS D 1 332 ? -21.993  -78.427  35.075  1.00 42.03  ? 332  LYS D C     1 
ATOM   12455 O O     . LYS D 1 332 ? -20.837  -78.059  35.217  1.00 41.88  ? 332  LYS D O     1 
ATOM   12456 C CB    . LYS D 1 332 ? -22.388  -80.268  36.795  1.00 57.08  ? 332  LYS D CB    1 
ATOM   12457 C CG    . LYS D 1 332 ? -22.377  -80.297  38.311  1.00 71.64  ? 332  LYS D CG    1 
ATOM   12458 C CD    . LYS D 1 332 ? -22.520  -81.638  39.012  1.00 83.37  ? 332  LYS D CD    1 
ATOM   12459 C CE    . LYS D 1 332 ? -22.740  -81.307  40.462  1.00 94.19  ? 332  LYS D CE    1 
ATOM   12460 N NZ    . LYS D 1 332 ? -23.012  -82.554  41.169  1.00 95.81  ? 332  LYS D NZ    1 
ATOM   12461 N N     . HIS D 1 333 ? -22.583  -78.470  33.867  1.00 36.09  ? 333  HIS D N     1 
ATOM   12462 C CA    . HIS D 1 333 ? -21.814  -78.255  32.647  1.00 27.59  ? 333  HIS D CA    1 
ATOM   12463 C C     . HIS D 1 333 ? -22.662  -77.601  31.559  1.00 29.73  ? 333  HIS D C     1 
ATOM   12464 O O     . HIS D 1 333 ? -23.891  -77.686  31.567  1.00 33.07  ? 333  HIS D O     1 
ATOM   12465 C CB    . HIS D 1 333 ? -21.282  -79.578  32.098  1.00 26.93  ? 333  HIS D CB    1 
ATOM   12466 C CG    . HIS D 1 333 ? -20.395  -80.337  33.026  1.00 32.98  ? 333  HIS D CG    1 
ATOM   12467 N ND1   . HIS D 1 333 ? -19.076  -79.980  33.276  1.00 32.04  ? 333  HIS D ND1   1 
ATOM   12468 C CD2   . HIS D 1 333 ? -20.627  -81.449  33.758  1.00 31.78  ? 333  HIS D CD2   1 
ATOM   12469 C CE1   . HIS D 1 333 ? -18.536  -80.843  34.137  1.00 27.42  ? 333  HIS D CE1   1 
ATOM   12470 N NE2   . HIS D 1 333 ? -19.453  -81.748  34.431  1.00 32.38  ? 333  HIS D NE2   1 
ATOM   12471 N N     . ASP D 1 334 ? -22.004  -76.963  30.594  1.00 25.02  ? 334  ASP D N     1 
ATOM   12472 C CA    . ASP D 1 334 ? -22.629  -76.694  29.313  1.00 21.94  ? 334  ASP D CA    1 
ATOM   12473 C C     . ASP D 1 334 ? -22.047  -77.660  28.288  1.00 24.82  ? 334  ASP D C     1 
ATOM   12474 O O     . ASP D 1 334 ? -20.932  -78.171  28.458  1.00 26.49  ? 334  ASP D O     1 
ATOM   12475 C CB    . ASP D 1 334 ? -22.525  -75.231  28.919  1.00 24.99  ? 334  ASP D CB    1 
ATOM   12476 C CG    . ASP D 1 334 ? -23.347  -74.305  29.804  1.00 27.99  ? 334  ASP D CG    1 
ATOM   12477 O OD1   . ASP D 1 334 ? -24.476  -74.698  30.181  1.00 29.20  ? 334  ASP D OD1   1 
ATOM   12478 O OD2   . ASP D 1 334 ? -22.844  -73.210  30.116  1.00 31.18  ? 334  ASP D OD2   1 
ATOM   12479 N N     . PHE D 1 335 ? -22.828  -77.925  27.230  1.00 24.93  ? 335  PHE D N     1 
ATOM   12480 C CA    . PHE D 1 335 ? -22.406  -78.816  26.158  1.00 19.19  ? 335  PHE D CA    1 
ATOM   12481 C C     . PHE D 1 335 ? -22.632  -78.100  24.832  1.00 20.92  ? 335  PHE D C     1 
ATOM   12482 O O     . PHE D 1 335 ? -23.707  -77.549  24.601  1.00 24.25  ? 335  PHE D O     1 
ATOM   12483 C CB    . PHE D 1 335 ? -23.220  -80.110  26.249  1.00 17.38  ? 335  PHE D CB    1 
ATOM   12484 C CG    . PHE D 1 335 ? -22.993  -80.922  27.512  1.00 17.76  ? 335  PHE D CG    1 
ATOM   12485 C CD1   . PHE D 1 335 ? -23.678  -80.611  28.698  1.00 19.11  ? 335  PHE D CD1   1 
ATOM   12486 C CD2   . PHE D 1 335 ? -22.120  -82.007  27.513  1.00 15.85  ? 335  PHE D CD2   1 
ATOM   12487 C CE1   . PHE D 1 335 ? -23.479  -81.370  29.850  1.00 21.02  ? 335  PHE D CE1   1 
ATOM   12488 C CE2   . PHE D 1 335 ? -21.927  -82.772  28.662  1.00 17.75  ? 335  PHE D CE2   1 
ATOM   12489 C CZ    . PHE D 1 335 ? -22.608  -82.455  29.839  1.00 19.98  ? 335  PHE D CZ    1 
ATOM   12490 N N     . LEU D 1 336 ? -21.595  -78.088  23.996  1.00 20.67  ? 336  LEU D N     1 
ATOM   12491 C CA    . LEU D 1 336 ? -21.663  -77.585  22.640  1.00 18.72  ? 336  LEU D CA    1 
ATOM   12492 C C     . LEU D 1 336 ? -22.031  -78.769  21.747  1.00 20.56  ? 336  LEU D C     1 
ATOM   12493 O O     . LEU D 1 336 ? -21.362  -79.812  21.753  1.00 23.70  ? 336  LEU D O     1 
ATOM   12494 C CB    . LEU D 1 336 ? -20.310  -76.995  22.229  1.00 20.20  ? 336  LEU D CB    1 
ATOM   12495 C CG    . LEU D 1 336 ? -19.708  -75.962  23.200  1.00 19.49  ? 336  LEU D CG    1 
ATOM   12496 C CD1   . LEU D 1 336 ? -18.336  -75.545  22.716  1.00 16.32  ? 336  LEU D CD1   1 
ATOM   12497 C CD2   . LEU D 1 336 ? -20.628  -74.745  23.337  1.00 17.99  ? 336  LEU D CD2   1 
ATOM   12498 N N     . CYS D 1 337 ? -23.140  -78.603  21.019  1.00 20.49  ? 337  CYS D N     1 
ATOM   12499 C CA    . CYS D 1 337 ? -23.598  -79.588  20.050  1.00 22.24  ? 337  CYS D CA    1 
ATOM   12500 C C     . CYS D 1 337 ? -23.249  -79.053  18.673  1.00 23.15  ? 337  CYS D C     1 
ATOM   12501 O O     . CYS D 1 337 ? -23.783  -78.025  18.249  1.00 21.20  ? 337  CYS D O     1 
ATOM   12502 C CB    . CYS D 1 337 ? -25.093  -79.863  20.218  1.00 24.09  ? 337  CYS D CB    1 
ATOM   12503 S SG    . CYS D 1 337 ? -25.504  -80.491  21.880  1.00 26.31  ? 337  CYS D SG    1 
ATOM   12504 N N     . ILE D 1 338 ? -22.325  -79.743  18.001  1.00 20.03  ? 338  ILE D N     1 
ATOM   12505 C CA    . ILE D 1 338 ? -21.696  -79.165  16.834  1.00 19.60  ? 338  ILE D CA    1 
ATOM   12506 C C     . ILE D 1 338 ? -22.000  -80.022  15.609  1.00 20.66  ? 338  ILE D C     1 
ATOM   12507 O O     . ILE D 1 338 ? -21.827  -81.235  15.646  1.00 19.94  ? 338  ILE D O     1 
ATOM   12508 C CB    . ILE D 1 338 ? -20.198  -78.952  17.124  1.00 20.38  ? 338  ILE D CB    1 
ATOM   12509 C CG1   . ILE D 1 338 ? -20.080  -77.828  18.180  1.00 21.44  ? 338  ILE D CG1   1 
ATOM   12510 C CG2   . ILE D 1 338 ? -19.468  -78.573  15.833  1.00 18.64  ? 338  ILE D CG2   1 
ATOM   12511 C CD1   . ILE D 1 338 ? -18.673  -77.544  18.636  1.00 24.93  ? 338  ILE D CD1   1 
ATOM   12512 N N     . LEU D 1 339 ? -22.533  -79.373  14.560  1.00 21.81  ? 339  LEU D N     1 
ATOM   12513 C CA    . LEU D 1 339 ? -22.994  -80.031  13.341  1.00 22.21  ? 339  LEU D CA    1 
ATOM   12514 C C     . LEU D 1 339 ? -22.057  -79.707  12.166  1.00 21.64  ? 339  LEU D C     1 
ATOM   12515 O O     . LEU D 1 339 ? -21.230  -78.783  12.246  1.00 17.83  ? 339  LEU D O     1 
ATOM   12516 C CB    . LEU D 1 339 ? -24.446  -79.647  13.027  1.00 21.26  ? 339  LEU D CB    1 
ATOM   12517 C CG    . LEU D 1 339 ? -25.509  -80.306  13.913  1.00 23.60  ? 339  LEU D CG    1 
ATOM   12518 C CD1   . LEU D 1 339 ? -25.562  -79.710  15.347  1.00 19.90  ? 339  LEU D CD1   1 
ATOM   12519 C CD2   . LEU D 1 339 ? -26.892  -80.307  13.261  1.00 21.45  ? 339  LEU D CD2   1 
ATOM   12520 N N     . ASP D 1 340 ? -22.191  -80.497  11.081  1.00 20.89  ? 340  ASP D N     1 
ATOM   12521 C CA    . ASP D 1 340 ? -21.504  -80.216  9.828   1.00 23.13  ? 340  ASP D CA    1 
ATOM   12522 C C     . ASP D 1 340 ? -19.996  -80.321  10.003  1.00 22.68  ? 340  ASP D C     1 
ATOM   12523 O O     . ASP D 1 340 ? -19.278  -79.519  9.438   1.00 25.47  ? 340  ASP D O     1 
ATOM   12524 C CB    . ASP D 1 340 ? -21.921  -78.874  9.240   1.00 22.90  ? 340  ASP D CB    1 
ATOM   12525 C CG    . ASP D 1 340 ? -23.437  -78.722  9.130   1.00 27.11  ? 340  ASP D CG    1 
ATOM   12526 O OD1   . ASP D 1 340 ? -24.053  -79.576  8.478   1.00 26.87  ? 340  ASP D OD1   1 
ATOM   12527 O OD2   . ASP D 1 340 ? -24.021  -77.802  9.770   1.00 28.76  ? 340  ASP D OD2   1 
ATOM   12528 N N     . LEU D 1 341 ? -19.527  -81.315  10.768  1.00 20.22  ? 341  LEU D N     1 
ATOM   12529 C CA    . LEU D 1 341 ? -18.106  -81.602  10.844  1.00 19.83  ? 341  LEU D CA    1 
ATOM   12530 C C     . LEU D 1 341 ? -17.745  -82.620  9.773   1.00 22.94  ? 341  LEU D C     1 
ATOM   12531 O O     . LEU D 1 341 ? -18.572  -83.445  9.373   1.00 23.22  ? 341  LEU D O     1 
ATOM   12532 C CB    . LEU D 1 341 ? -17.719  -82.130  12.219  1.00 17.05  ? 341  LEU D CB    1 
ATOM   12533 C CG    . LEU D 1 341 ? -17.803  -81.082  13.336  1.00 18.02  ? 341  LEU D CG    1 
ATOM   12534 C CD1   . LEU D 1 341 ? -17.511  -81.763  14.668  1.00 19.04  ? 341  LEU D CD1   1 
ATOM   12535 C CD2   . LEU D 1 341 ? -16.927  -79.869  13.086  1.00 15.30  ? 341  LEU D CD2   1 
ATOM   12536 N N     . GLN D 1 342 ? -16.468  -82.603  9.373   1.00 23.43  ? 342  GLN D N     1 
ATOM   12537 C CA    . GLN D 1 342 ? -15.992  -83.616  8.449   1.00 24.32  ? 342  GLN D CA    1 
ATOM   12538 C C     . GLN D 1 342 ? -14.942  -84.519  9.092   1.00 24.24  ? 342  GLN D C     1 
ATOM   12539 O O     . GLN D 1 342 ? -14.472  -84.250  10.200  1.00 24.20  ? 342  GLN D O     1 
ATOM   12540 C CB    . GLN D 1 342 ? -15.570  -82.852  7.216   1.00 24.38  ? 342  GLN D CB    1 
ATOM   12541 C CG    . GLN D 1 342 ? -16.783  -82.335  6.455   1.00 35.62  ? 342  GLN D CG    1 
ATOM   12542 C CD    . GLN D 1 342 ? -16.347  -81.649  5.185   1.00 46.33  ? 342  GLN D CD    1 
ATOM   12543 O OE1   . GLN D 1 342 ? -15.823  -80.530  5.207   1.00 50.07  ? 342  GLN D OE1   1 
ATOM   12544 N NE2   . GLN D 1 342 ? -16.467  -82.366  4.082   1.00 48.41  ? 342  GLN D NE2   1 
ATOM   12545 N N     . VAL D 1 343 ? -14.588  -85.590  8.380   1.00 24.45  ? 343  VAL D N     1 
ATOM   12546 C CA    . VAL D 1 343 ? -13.572  -86.533  8.829   1.00 24.51  ? 343  VAL D CA    1 
ATOM   12547 C C     . VAL D 1 343 ? -12.174  -85.988  8.536   1.00 26.98  ? 343  VAL D C     1 
ATOM   12548 O O     . VAL D 1 343 ? -11.963  -85.277  7.543   1.00 29.37  ? 343  VAL D O     1 
ATOM   12549 C CB    . VAL D 1 343 ? -13.831  -87.897  8.156   1.00 26.32  ? 343  VAL D CB    1 
ATOM   12550 C CG1   . VAL D 1 343 ? -12.834  -88.943  8.632   1.00 25.52  ? 343  VAL D CG1   1 
ATOM   12551 C CG2   . VAL D 1 343 ? -15.276  -88.377  8.396   1.00 21.59  ? 343  VAL D CG2   1 
ATOM   12552 N N     . VAL D 1 344 ? -11.231  -86.288  9.435   1.00 27.78  ? 344  VAL D N     1 
ATOM   12553 C CA    . VAL D 1 344 ? -9.840   -85.863  9.293   1.00 32.42  ? 344  VAL D CA    1 
ATOM   12554 C C     . VAL D 1 344 ? -9.022   -86.983  8.633   1.00 37.40  ? 344  VAL D C     1 
ATOM   12555 O O     . VAL D 1 344 ? -8.927   -88.075  9.203   1.00 31.12  ? 344  VAL D O     1 
ATOM   12556 C CB    . VAL D 1 344 ? -9.281   -85.559  10.704  1.00 31.78  ? 344  VAL D CB    1 
ATOM   12557 C CG1   . VAL D 1 344 ? -7.773   -85.325  10.691  1.00 33.28  ? 344  VAL D CG1   1 
ATOM   12558 C CG2   . VAL D 1 344 ? -9.960   -84.358  11.340  1.00 29.77  ? 344  VAL D CG2   1 
ATOM   12559 N N     . GLY D 1 345 ? -8.402   -86.687  7.471   1.00 43.09  ? 345  GLY D N     1 
ATOM   12560 C CA    . GLY D 1 345 ? -7.393   -87.534  6.840   1.00 44.87  ? 345  GLY D CA    1 
ATOM   12561 C C     . GLY D 1 345 ? -5.976   -87.301  7.392   1.00 48.89  ? 345  GLY D C     1 
ATOM   12562 O O     . GLY D 1 345 ? -5.760   -87.069  8.589   1.00 48.23  ? 345  GLY D O     1 
ATOM   12563 N N     . LYS D 1 346 ? -4.996   -87.585  6.557   1.00 53.38  ? 346  LYS D N     1 
ATOM   12564 C CA    . LYS D 1 346 ? -3.602   -87.389  6.897   1.00 57.37  ? 346  LYS D CA    1 
ATOM   12565 C C     . LYS D 1 346 ? -2.781   -87.040  5.685   1.00 59.02  ? 346  LYS D C     1 
ATOM   12566 O O     . LYS D 1 346 ? -2.894   -87.695  4.678   1.00 45.98  ? 346  LYS D O     1 
ATOM   12567 C CB    . LYS D 1 346 ? -3.002   -88.628  7.556   1.00 59.16  ? 346  LYS D CB    1 
ATOM   12568 C CG    . LYS D 1 346 ? -1.729   -88.314  8.304   1.00 66.29  ? 346  LYS D CG    1 
ATOM   12569 C CD    . LYS D 1 346 ? -1.035   -89.547  8.812   1.00 75.74  ? 346  LYS D CD    1 
ATOM   12570 C CE    . LYS D 1 346 ? -0.328   -89.269  10.121  1.00 84.97  ? 346  LYS D CE    1 
ATOM   12571 N NZ    . LYS D 1 346 ? 0.376    -90.456  10.672  1.00 79.73  ? 346  LYS D NZ    1 
ATOM   12572 N N     . ASP D 1 347 ? -1.968   -85.993  5.805   1.00 65.13  ? 347  ASP D N     1 
ATOM   12573 C CA    . ASP D 1 347 ? -1.056   -85.565  4.763   1.00 66.39  ? 347  ASP D CA    1 
ATOM   12574 C C     . ASP D 1 347 ? -1.800   -85.336  3.481   1.00 68.37  ? 347  ASP D C     1 
ATOM   12575 O O     . ASP D 1 347 ? -2.590   -84.439  3.362   1.00 74.02  ? 347  ASP D O     1 
ATOM   12576 C CB    . ASP D 1 347 ? 0.102    -86.537  4.585   1.00 81.39  ? 347  ASP D CB    1 
ATOM   12577 C CG    . ASP D 1 347 ? 0.824    -86.826  5.876   1.00 87.11  ? 347  ASP D CG    1 
ATOM   12578 O OD1   . ASP D 1 347 ? 1.160    -85.891  6.599   1.00 96.36  ? 347  ASP D OD1   1 
ATOM   12579 O OD2   . ASP D 1 347 ? 1.074    -87.993  6.176   1.00 82.16  ? 347  ASP D OD2   1 
ATOM   12580 N N     . ASN D 1 348 ? -1.460   -86.131  2.500   1.00 67.70  ? 348  ASN D N     1 
ATOM   12581 C CA    . ASN D 1 348 ? -2.082   -86.120  1.210   1.00 83.25  ? 348  ASN D CA    1 
ATOM   12582 C C     . ASN D 1 348 ? -3.543   -86.447  1.217   1.00 81.14  ? 348  ASN D C     1 
ATOM   12583 O O     . ASN D 1 348 ? -4.272   -85.928  0.409   1.00 83.04  ? 348  ASN D O     1 
ATOM   12584 C CB    . ASN D 1 348 ? -1.432   -87.170  0.340   1.00 93.23  ? 348  ASN D CB    1 
ATOM   12585 C CG    . ASN D 1 348 ? -0.200   -86.668  -0.298  1.00 99.61  ? 348  ASN D CG    1 
ATOM   12586 O OD1   . ASN D 1 348 ? 0.557    -87.426  -0.874  1.00 98.54  ? 348  ASN D OD1   1 
ATOM   12587 N ND2   . ASN D 1 348 ? 0.019    -85.364  -0.197  1.00 98.32  ? 348  ASN D ND2   1 
ATOM   12588 N N     . VAL D 1 349 ? -3.975   -87.351  2.074   1.00 70.47  ? 349  VAL D N     1 
ATOM   12589 C CA    . VAL D 1 349 ? -5.372   -87.694  2.071   1.00 67.74  ? 349  VAL D CA    1 
ATOM   12590 C C     . VAL D 1 349 ? -6.160   -86.661  2.849   1.00 65.42  ? 349  VAL D C     1 
ATOM   12591 O O     . VAL D 1 349 ? -6.143   -86.621  4.056   1.00 53.34  ? 349  VAL D O     1 
ATOM   12592 C CB    . VAL D 1 349 ? -5.583   -89.059  2.709   1.00 62.47  ? 349  VAL D CB    1 
ATOM   12593 C CG1   . VAL D 1 349 ? -6.911   -89.643  2.297   1.00 58.79  ? 349  VAL D CG1   1 
ATOM   12594 C CG2   . VAL D 1 349 ? -4.470   -89.977  2.304   1.00 60.84  ? 349  VAL D CG2   1 
ATOM   12595 N N     . VAL D 1 350 ? -6.886   -85.845  2.114   1.00 57.33  ? 350  VAL D N     1 
ATOM   12596 C CA    . VAL D 1 350 ? -7.684   -84.807  2.708   1.00 60.64  ? 350  VAL D CA    1 
ATOM   12597 C C     . VAL D 1 350 ? -9.124   -85.146  2.530   1.00 52.10  ? 350  VAL D C     1 
ATOM   12598 O O     . VAL D 1 350 ? -9.609   -85.328  1.450   1.00 54.26  ? 350  VAL D O     1 
ATOM   12599 C CB    . VAL D 1 350 ? -7.339   -83.409  2.195   1.00 61.75  ? 350  VAL D CB    1 
ATOM   12600 C CG1   . VAL D 1 350 ? -6.192   -83.463  1.226   1.00 56.70  ? 350  VAL D CG1   1 
ATOM   12601 C CG2   . VAL D 1 350 ? -8.550   -82.734  1.624   1.00 54.93  ? 350  VAL D CG2   1 
ATOM   12602 N N     . LEU D 1 351 ? -9.789   -85.185  3.653   1.00 52.05  ? 351  LEU D N     1 
ATOM   12603 C CA    . LEU D 1 351 ? -11.185  -85.618  3.757   1.00 45.88  ? 351  LEU D CA    1 
ATOM   12604 C C     . LEU D 1 351 ? -12.132  -84.449  4.089   1.00 42.35  ? 351  LEU D C     1 
ATOM   12605 O O     . LEU D 1 351 ? -13.343  -84.603  3.975   1.00 42.99  ? 351  LEU D O     1 
ATOM   12606 C CB    . LEU D 1 351 ? -11.331  -86.810  4.707   1.00 42.86  ? 351  LEU D CB    1 
ATOM   12607 C CG    . LEU D 1 351 ? -10.456  -88.031  4.385   1.00 44.49  ? 351  LEU D CG    1 
ATOM   12608 C CD1   . LEU D 1 351 ? -10.509  -89.029  5.534   1.00 39.68  ? 351  LEU D CD1   1 
ATOM   12609 C CD2   . LEU D 1 351 ? -10.797  -88.703  3.058   1.00 39.05  ? 351  LEU D CD2   1 
ATOM   12610 N N     . GLY D 1 352 ? -11.591  -83.279  4.479   1.00 36.87  ? 352  GLY D N     1 
ATOM   12611 C CA    . GLY D 1 352 ? -12.381  -82.073  4.682   1.00 35.00  ? 352  GLY D CA    1 
ATOM   12612 C C     . GLY D 1 352 ? -12.235  -81.477  6.090   1.00 39.36  ? 352  GLY D C     1 
ATOM   12613 O O     . GLY D 1 352 ? -12.450  -80.280  6.263   1.00 44.27  ? 352  GLY D O     1 
ATOM   12614 N N     . GLY D 1 353 ? -11.873  -82.293  7.096   1.00 41.51  ? 353  GLY D N     1 
ATOM   12615 C CA    . GLY D 1 353 ? -11.947  -81.868  8.486   1.00 40.18  ? 353  GLY D CA    1 
ATOM   12616 C C     . GLY D 1 353 ? -10.627  -81.324  9.060   1.00 44.43  ? 353  GLY D C     1 
ATOM   12617 O O     . GLY D 1 353 ? -10.584  -80.973  10.252  1.00 37.23  ? 353  GLY D O     1 
ATOM   12618 N N     . GLU D 1 354 ? -9.566   -81.208  8.234   1.00 40.51  ? 354  GLU D N     1 
ATOM   12619 C CA    . GLU D 1 354 ? -8.216   -81.049  8.783   1.00 47.43  ? 354  GLU D CA    1 
ATOM   12620 C C     . GLU D 1 354 ? -7.842   -79.617  9.210   1.00 45.34  ? 354  GLU D C     1 
ATOM   12621 O O     . GLU D 1 354 ? -7.048   -79.470  10.150  1.00 45.57  ? 354  GLU D O     1 
ATOM   12622 C CB    . GLU D 1 354 ? -7.078   -81.886  8.175   1.00 51.22  ? 354  GLU D CB    1 
ATOM   12623 C CG    . GLU D 1 354 ? -7.133   -82.054  6.660   1.00 52.02  ? 354  GLU D CG    1 
ATOM   12624 C CD    . GLU D 1 354 ? -8.272   -82.925  6.100   1.00 52.07  ? 354  GLU D CD    1 
ATOM   12625 O OE1   . GLU D 1 354 ? -9.168   -82.274  5.508   1.00 50.76  ? 354  GLU D OE1   1 
ATOM   12626 O OE2   . GLU D 1 354 ? -8.281   -84.187  6.171   1.00 39.69  ? 354  GLU D OE2   1 
ATOM   12627 N N     . GLY D 1 355 ? -8.388   -78.564  8.566   1.00 36.35  ? 355  GLY D N     1 
ATOM   12628 C CA    . GLY D 1 355 ? -7.965   -77.218  8.948   1.00 30.06  ? 355  GLY D CA    1 
ATOM   12629 C C     . GLY D 1 355 ? -8.547   -76.822  10.311  1.00 31.01  ? 355  GLY D C     1 
ATOM   12630 O O     . GLY D 1 355 ? -9.534   -77.412  10.772  1.00 34.38  ? 355  GLY D O     1 
ATOM   12631 N N     . VAL D 1 356 ? -7.955   -75.816  10.958  1.00 25.69  ? 356  VAL D N     1 
ATOM   12632 C CA    . VAL D 1 356 ? -8.584   -75.237  12.133  1.00 24.69  ? 356  VAL D CA    1 
ATOM   12633 C C     . VAL D 1 356 ? -10.003  -74.759  11.781  1.00 24.85  ? 356  VAL D C     1 
ATOM   12634 O O     . VAL D 1 356 ? -10.230  -74.150  10.736  1.00 21.78  ? 356  VAL D O     1 
ATOM   12635 C CB    . VAL D 1 356 ? -7.668   -74.081  12.580  1.00 24.22  ? 356  VAL D CB    1 
ATOM   12636 C CG1   . VAL D 1 356 ? -8.263   -73.328  13.765  1.00 20.90  ? 356  VAL D CG1   1 
ATOM   12637 C CG2   . VAL D 1 356 ? -6.300   -74.609  12.973  1.00 19.36  ? 356  VAL D CG2   1 
ATOM   12638 N N     . ASN D 1 357 ? -10.957  -75.000  12.692  1.00 23.37  ? 357  ASN D N     1 
ATOM   12639 C CA    . ASN D 1 357 ? -12.378  -74.842  12.395  1.00 20.39  ? 357  ASN D CA    1 
ATOM   12640 C C     . ASN D 1 357 ? -13.021  -74.049  13.530  1.00 20.17  ? 357  ASN D C     1 
ATOM   12641 O O     . ASN D 1 357 ? -13.647  -74.613  14.434  1.00 20.67  ? 357  ASN D O     1 
ATOM   12642 C CB    . ASN D 1 357 ? -13.012  -76.220  12.185  1.00 21.01  ? 357  ASN D CB    1 
ATOM   12643 C CG    . ASN D 1 357 ? -14.508  -76.208  11.970  1.00 25.95  ? 357  ASN D CG    1 
ATOM   12644 O OD1   . ASN D 1 357 ? -15.123  -75.196  11.591  1.00 23.50  ? 357  ASN D OD1   1 
ATOM   12645 N ND2   . ASN D 1 357 ? -15.133  -77.341  12.250  1.00 30.37  ? 357  ASN D ND2   1 
ATOM   12646 N N     . PRO D 1 358 ? -12.881  -72.706  13.545  1.00 20.46  ? 358  PRO D N     1 
ATOM   12647 C CA    . PRO D 1 358 ? -13.424  -71.903  14.638  1.00 19.91  ? 358  PRO D CA    1 
ATOM   12648 C C     . PRO D 1 358 ? -14.949  -71.845  14.661  1.00 21.26  ? 358  PRO D C     1 
ATOM   12649 O O     . PRO D 1 358 ? -15.552  -71.382  13.685  1.00 24.17  ? 358  PRO D O     1 
ATOM   12650 C CB    . PRO D 1 358 ? -12.811  -70.507  14.437  1.00 17.71  ? 358  PRO D CB    1 
ATOM   12651 C CG    . PRO D 1 358 ? -12.328  -70.532  13.036  1.00 17.97  ? 358  PRO D CG    1 
ATOM   12652 C CD    . PRO D 1 358 ? -12.171  -71.920  12.536  1.00 18.88  ? 358  PRO D CD    1 
ATOM   12653 N N     . ARG D 1 359 ? -15.558  -72.337  15.751  1.00 17.38  ? 359  ARG D N     1 
ATOM   12654 C CA    . ARG D 1 359 ? -16.993  -72.275  15.937  1.00 16.49  ? 359  ARG D CA    1 
ATOM   12655 C C     . ARG D 1 359 ? -17.261  -71.422  17.168  1.00 19.85  ? 359  ARG D C     1 
ATOM   12656 O O     . ARG D 1 359 ? -16.724  -71.705  18.238  1.00 21.55  ? 359  ARG D O     1 
ATOM   12657 C CB    . ARG D 1 359 ? -17.620  -73.666  16.106  1.00 17.15  ? 359  ARG D CB    1 
ATOM   12658 C CG    . ARG D 1 359 ? -17.379  -74.622  14.939  1.00 16.28  ? 359  ARG D CG    1 
ATOM   12659 C CD    . ARG D 1 359 ? -18.090  -74.086  13.651  1.00 16.66  ? 359  ARG D CD    1 
ATOM   12660 N NE    . ARG D 1 359 ? -17.969  -75.068  12.559  1.00 18.77  ? 359  ARG D NE    1 
ATOM   12661 C CZ    . ARG D 1 359 ? -18.796  -76.092  12.349  1.00 18.65  ? 359  ARG D CZ    1 
ATOM   12662 N NH1   . ARG D 1 359 ? -19.883  -76.233  13.103  1.00 18.27  ? 359  ARG D NH1   1 
ATOM   12663 N NH2   . ARG D 1 359 ? -18.523  -76.986  11.402  1.00 20.07  ? 359  ARG D NH2   1 
ATOM   12664 N N     . SER D 1 360 ? -18.114  -70.395  17.008  1.00 18.44  ? 360  SER D N     1 
ATOM   12665 C CA    . SER D 1 360 ? -18.347  -69.421  18.042  1.00 21.53  ? 360  SER D CA    1 
ATOM   12666 C C     . SER D 1 360 ? -19.774  -69.481  18.593  1.00 23.22  ? 360  SER D C     1 
ATOM   12667 O O     . SER D 1 360 ? -20.699  -69.930  17.919  1.00 22.07  ? 360  SER D O     1 
ATOM   12668 C CB    . SER D 1 360 ? -18.012  -68.033  17.554  1.00 24.34  ? 360  SER D CB    1 
ATOM   12669 O OG    . SER D 1 360 ? -16.621  -67.951  17.275  1.00 22.56  ? 360  SER D OG    1 
ATOM   12670 N N     . PHE D 1 361 ? -19.903  -68.979  19.830  1.00 18.89  ? 361  PHE D N     1 
ATOM   12671 C CA    . PHE D 1 361 ? -21.127  -68.956  20.602  1.00 19.06  ? 361  PHE D CA    1 
ATOM   12672 C C     . PHE D 1 361 ? -21.131  -67.643  21.376  1.00 19.57  ? 361  PHE D C     1 
ATOM   12673 O O     . PHE D 1 361 ? -20.076  -67.142  21.740  1.00 24.53  ? 361  PHE D O     1 
ATOM   12674 C CB    . PHE D 1 361 ? -21.093  -70.130  21.592  1.00 16.49  ? 361  PHE D CB    1 
ATOM   12675 C CG    . PHE D 1 361 ? -20.981  -71.452  20.853  1.00 17.82  ? 361  PHE D CG    1 
ATOM   12676 C CD1   . PHE D 1 361 ? -22.137  -72.121  20.419  1.00 17.38  ? 361  PHE D CD1   1 
ATOM   12677 C CD2   . PHE D 1 361 ? -19.724  -71.987  20.529  1.00 18.51  ? 361  PHE D CD2   1 
ATOM   12678 C CE1   . PHE D 1 361 ? -22.036  -73.330  19.730  1.00 18.48  ? 361  PHE D CE1   1 
ATOM   12679 C CE2   . PHE D 1 361 ? -19.625  -73.184  19.817  1.00 19.80  ? 361  PHE D CE2   1 
ATOM   12680 C CZ    . PHE D 1 361 ? -20.783  -73.844  19.402  1.00 19.06  ? 361  PHE D CZ    1 
ATOM   12681 N N     . VAL D 1 362 ? -22.330  -67.114  21.610  1.00 19.78  ? 362  VAL D N     1 
ATOM   12682 C CA    . VAL D 1 362 ? -22.539  -65.845  22.271  1.00 21.66  ? 362  VAL D CA    1 
ATOM   12683 C C     . VAL D 1 362 ? -23.481  -66.116  23.435  1.00 23.20  ? 362  VAL D C     1 
ATOM   12684 O O     . VAL D 1 362 ? -24.582  -66.630  23.219  1.00 20.83  ? 362  VAL D O     1 
ATOM   12685 C CB    . VAL D 1 362 ? -23.218  -64.840  21.313  1.00 21.85  ? 362  VAL D CB    1 
ATOM   12686 C CG1   . VAL D 1 362 ? -23.517  -63.534  22.069  1.00 20.35  ? 362  VAL D CG1   1 
ATOM   12687 C CG2   . VAL D 1 362 ? -22.389  -64.628  20.051  1.00 18.25  ? 362  VAL D CG2   1 
ATOM   12688 N N     . GLY D 1 363 ? -23.050  -65.736  24.648  1.00 23.58  ? 363  GLY D N     1 
ATOM   12689 C CA    . GLY D 1 363 ? -23.889  -65.903  25.823  1.00 23.77  ? 363  GLY D CA    1 
ATOM   12690 C C     . GLY D 1 363 ? -23.181  -66.685  26.935  1.00 28.16  ? 363  GLY D C     1 
ATOM   12691 O O     . GLY D 1 363 ? -23.769  -66.912  27.984  1.00 28.48  ? 363  GLY D O     1 
ATOM   12692 N N     . ILE D 1 364 ? -21.916  -67.069  26.742  1.00 29.11  ? 364  ILE D N     1 
ATOM   12693 C CA    . ILE D 1 364 ? -21.170  -67.698  27.821  1.00 31.97  ? 364  ILE D CA    1 
ATOM   12694 C C     . ILE D 1 364 ? -20.274  -66.660  28.500  1.00 31.94  ? 364  ILE D C     1 
ATOM   12695 O O     . ILE D 1 364 ? -19.355  -66.120  27.889  1.00 28.00  ? 364  ILE D O     1 
ATOM   12696 C CB    . ILE D 1 364 ? -20.408  -68.904  27.250  1.00 34.05  ? 364  ILE D CB    1 
ATOM   12697 C CG1   . ILE D 1 364 ? -21.442  -70.012  26.962  1.00 32.78  ? 364  ILE D CG1   1 
ATOM   12698 C CG2   . ILE D 1 364 ? -19.305  -69.366  28.199  1.00 31.31  ? 364  ILE D CG2   1 
ATOM   12699 C CD1   . ILE D 1 364 ? -20.855  -71.197  26.270  1.00 32.74  ? 364  ILE D CD1   1 
ATOM   12700 N N     . GLY D 1 365 ? -20.574  -66.375  29.770  1.00 33.31  ? 365  GLY D N     1 
ATOM   12701 C CA    . GLY D 1 365 ? -19.971  -65.273  30.519  1.00 31.67  ? 365  GLY D CA    1 
ATOM   12702 C C     . GLY D 1 365 ? -18.951  -65.711  31.580  1.00 31.90  ? 365  GLY D C     1 
ATOM   12703 O O     . GLY D 1 365 ? -18.254  -64.880  32.129  1.00 38.52  ? 365  GLY D O     1 
ATOM   12704 N N     . GLN D 1 366 ? -18.800  -67.011  31.827  1.00 32.10  ? 366  GLN D N     1 
ATOM   12705 C CA    . GLN D 1 366 ? -17.947  -67.522  32.892  1.00 34.49  ? 366  GLN D CA    1 
ATOM   12706 C C     . GLN D 1 366 ? -16.643  -68.060  32.312  1.00 36.52  ? 366  GLN D C     1 
ATOM   12707 O O     . GLN D 1 366 ? -16.648  -68.672  31.245  1.00 32.54  ? 366  GLN D O     1 
ATOM   12708 C CB    . GLN D 1 366 ? -18.667  -68.626  33.682  1.00 37.94  ? 366  GLN D CB    1 
ATOM   12709 C CG    . GLN D 1 366 ? -19.862  -68.126  34.500  1.00 51.22  ? 366  GLN D CG    1 
ATOM   12710 C CD    . GLN D 1 366 ? -19.562  -66.869  35.313  1.00 58.72  ? 366  GLN D CD    1 
ATOM   12711 O OE1   . GLN D 1 366 ? -18.637  -66.843  36.130  1.00 63.63  ? 366  GLN D OE1   1 
ATOM   12712 N NE2   . GLN D 1 366 ? -20.319  -65.798  35.105  1.00 52.30  ? 366  GLN D NE2   1 
ATOM   12713 N N     . PRO D 1 367 ? -15.484  -67.873  32.988  1.00 33.29  ? 367  PRO D N     1 
ATOM   12714 C CA    . PRO D 1 367 ? -14.236  -68.451  32.501  1.00 27.77  ? 367  PRO D CA    1 
ATOM   12715 C C     . PRO D 1 367 ? -14.270  -69.978  32.458  1.00 31.91  ? 367  PRO D C     1 
ATOM   12716 O O     . PRO D 1 367 ? -14.801  -70.613  33.367  1.00 29.16  ? 367  PRO D O     1 
ATOM   12717 C CB    . PRO D 1 367 ? -13.157  -67.962  33.480  1.00 27.18  ? 367  PRO D CB    1 
ATOM   12718 C CG    . PRO D 1 367 ? -13.921  -67.323  34.655  1.00 25.36  ? 367  PRO D CG    1 
ATOM   12719 C CD    . PRO D 1 367 ? -15.342  -67.074  34.218  1.00 28.93  ? 367  PRO D CD    1 
ATOM   12720 N N     . ILE D 1 368 ? -13.638  -70.560  31.429  1.00 29.50  ? 368  ILE D N     1 
ATOM   12721 C CA    . ILE D 1 368 ? -13.738  -71.988  31.207  1.00 25.93  ? 368  ILE D CA    1 
ATOM   12722 C C     . ILE D 1 368 ? -12.389  -72.598  31.557  1.00 30.19  ? 368  ILE D C     1 
ATOM   12723 O O     . ILE D 1 368 ? -11.345  -72.042  31.227  1.00 32.08  ? 368  ILE D O     1 
ATOM   12724 C CB    . ILE D 1 368 ? -14.161  -72.286  29.748  1.00 25.82  ? 368  ILE D CB    1 
ATOM   12725 C CG1   . ILE D 1 368 ? -15.655  -72.022  29.534  1.00 23.18  ? 368  ILE D CG1   1 
ATOM   12726 C CG2   . ILE D 1 368 ? -13.780  -73.704  29.324  1.00 20.77  ? 368  ILE D CG2   1 
ATOM   12727 C CD1   . ILE D 1 368 ? -16.083  -71.872  28.078  1.00 21.16  ? 368  ILE D CD1   1 
ATOM   12728 N N     . GLN D 1 369 ? -12.412  -73.786  32.163  1.00 29.14  ? 369  GLN D N     1 
ATOM   12729 C CA    . GLN D 1 369 ? -11.174  -74.473  32.436  1.00 29.93  ? 369  GLN D CA    1 
ATOM   12730 C C     . GLN D 1 369 ? -10.802  -75.406  31.293  1.00 30.01  ? 369  GLN D C     1 
ATOM   12731 O O     . GLN D 1 369 ? -9.642   -75.457  30.897  1.00 31.09  ? 369  GLN D O     1 
ATOM   12732 C CB    . GLN D 1 369 ? -11.308  -75.246  33.745  1.00 39.03  ? 369  GLN D CB    1 
ATOM   12733 C CG    . GLN D 1 369 ? -10.006  -75.875  34.221  1.00 64.08  ? 369  GLN D CG    1 
ATOM   12734 C CD    . GLN D 1 369 ? -10.287  -77.117  35.034  1.00 90.27  ? 369  GLN D CD    1 
ATOM   12735 O OE1   . GLN D 1 369 ? -10.974  -77.064  36.064  1.00 87.22  ? 369  GLN D OE1   1 
ATOM   12736 N NE2   . GLN D 1 369 ? -9.783   -78.256  34.568  1.00 102.66 ? 369  GLN D NE2   1 
ATOM   12737 N N     . ARG D 1 370 ? -11.759  -76.184  30.774  1.00 29.10  ? 370  ARG D N     1 
ATOM   12738 C CA    . ARG D 1 370 ? -11.431  -77.215  29.809  1.00 30.39  ? 370  ARG D CA    1 
ATOM   12739 C C     . ARG D 1 370 ? -12.674  -77.532  28.972  1.00 31.41  ? 370  ARG D C     1 
ATOM   12740 O O     . ARG D 1 370 ? -13.812  -77.474  29.461  1.00 27.09  ? 370  ARG D O     1 
ATOM   12741 C CB    . ARG D 1 370 ? -11.056  -78.434  30.662  1.00 32.55  ? 370  ARG D CB    1 
ATOM   12742 C CG    . ARG D 1 370 ? -10.101  -79.447  30.070  1.00 43.99  ? 370  ARG D CG    1 
ATOM   12743 C CD    . ARG D 1 370 ? -9.752   -80.405  31.218  1.00 60.00  ? 370  ARG D CD    1 
ATOM   12744 N NE    . ARG D 1 370 ? -9.598   -81.753  30.668  1.00 84.20  ? 370  ARG D NE    1 
ATOM   12745 C CZ    . ARG D 1 370 ? -10.445  -82.780  30.802  1.00 94.77  ? 370  ARG D CZ    1 
ATOM   12746 N NH1   . ARG D 1 370 ? -11.495  -82.687  31.612  1.00 88.77  ? 370  ARG D NH1   1 
ATOM   12747 N NH2   . ARG D 1 370 ? -10.224  -83.900  30.117  1.00 85.16  ? 370  ARG D NH2   1 
ATOM   12748 N N     . ILE D 1 371 ? -12.448  -77.910  27.709  1.00 26.91  ? 371  ILE D N     1 
ATOM   12749 C CA    . ILE D 1 371 ? -13.508  -78.363  26.821  1.00 23.04  ? 371  ILE D CA    1 
ATOM   12750 C C     . ILE D 1 371 ? -13.016  -79.652  26.167  1.00 25.12  ? 371  ILE D C     1 
ATOM   12751 O O     . ILE D 1 371 ? -11.895  -79.691  25.662  1.00 23.67  ? 371  ILE D O     1 
ATOM   12752 C CB    . ILE D 1 371 ? -13.827  -77.294  25.756  1.00 19.35  ? 371  ILE D CB    1 
ATOM   12753 C CG1   . ILE D 1 371 ? -14.095  -75.926  26.401  1.00 17.87  ? 371  ILE D CG1   1 
ATOM   12754 C CG2   . ILE D 1 371 ? -15.011  -77.752  24.894  1.00 18.28  ? 371  ILE D CG2   1 
ATOM   12755 C CD1   . ILE D 1 371 ? -14.522  -74.824  25.422  1.00 19.27  ? 371  ILE D CD1   1 
ATOM   12756 N N     . HIS D 1 372 ? -13.873  -80.682  26.095  1.00 23.37  ? 372  HIS D N     1 
ATOM   12757 C CA    . HIS D 1 372 ? -13.453  -81.928  25.470  1.00 23.55  ? 372  HIS D CA    1 
ATOM   12758 C C     . HIS D 1 372 ? -14.627  -82.611  24.762  1.00 24.37  ? 372  HIS D C     1 
ATOM   12759 O O     . HIS D 1 372 ? -15.768  -82.547  25.226  1.00 28.28  ? 372  HIS D O     1 
ATOM   12760 C CB    . HIS D 1 372 ? -12.756  -82.842  26.492  1.00 23.59  ? 372  HIS D CB    1 
ATOM   12761 C CG    . HIS D 1 372 ? -13.671  -83.354  27.553  1.00 30.18  ? 372  HIS D CG    1 
ATOM   12762 N ND1   . HIS D 1 372 ? -13.957  -82.675  28.737  1.00 36.21  ? 372  HIS D ND1   1 
ATOM   12763 C CD2   . HIS D 1 372 ? -14.369  -84.522  27.587  1.00 31.65  ? 372  HIS D CD2   1 
ATOM   12764 C CE1   . HIS D 1 372 ? -14.811  -83.421  29.456  1.00 34.83  ? 372  HIS D CE1   1 
ATOM   12765 N NE2   . HIS D 1 372 ? -15.065  -84.542  28.776  1.00 35.64  ? 372  HIS D NE2   1 
ATOM   12766 N N     . TRP D 1 373 ? -14.326  -83.286  23.646  1.00 22.46  ? 373  TRP D N     1 
ATOM   12767 C CA    . TRP D 1 373 ? -15.301  -84.106  22.938  1.00 24.05  ? 373  TRP D CA    1 
ATOM   12768 C C     . TRP D 1 373 ? -15.723  -85.291  23.814  1.00 25.06  ? 373  TRP D C     1 
ATOM   12769 O O     . TRP D 1 373 ? -14.864  -86.004  24.348  1.00 30.64  ? 373  TRP D O     1 
ATOM   12770 C CB    . TRP D 1 373 ? -14.688  -84.626  21.629  1.00 20.79  ? 373  TRP D CB    1 
ATOM   12771 C CG    . TRP D 1 373 ? -14.476  -83.601  20.536  1.00 21.15  ? 373  TRP D CG    1 
ATOM   12772 C CD1   . TRP D 1 373 ? -13.316  -83.440  19.828  1.00 20.23  ? 373  TRP D CD1   1 
ATOM   12773 C CD2   . TRP D 1 373 ? -15.429  -82.682  19.948  1.00 18.83  ? 373  TRP D CD2   1 
ATOM   12774 N NE1   . TRP D 1 373 ? -13.462  -82.461  18.879  1.00 18.23  ? 373  TRP D NE1   1 
ATOM   12775 C CE2   . TRP D 1 373 ? -14.747  -81.985  18.918  1.00 18.54  ? 373  TRP D CE2   1 
ATOM   12776 C CE3   . TRP D 1 373 ? -16.778  -82.364  20.184  1.00 19.53  ? 373  TRP D CE3   1 
ATOM   12777 C CZ2   . TRP D 1 373 ? -15.358  -80.994  18.128  1.00 17.76  ? 373  TRP D CZ2   1 
ATOM   12778 C CZ3   . TRP D 1 373 ? -17.395  -81.406  19.402  1.00 16.19  ? 373  TRP D CZ3   1 
ATOM   12779 C CH2   . TRP D 1 373 ? -16.689  -80.727  18.393  1.00 18.40  ? 373  TRP D CH2   1 
ATOM   12780 N N     . LEU D 1 374 ? -17.032  -85.562  23.887  1.00 22.95  ? 374  LEU D N     1 
ATOM   12781 C CA    . LEU D 1 374 ? -17.550  -86.733  24.591  1.00 21.13  ? 374  LEU D CA    1 
ATOM   12782 C C     . LEU D 1 374 ? -17.114  -88.022  23.923  1.00 25.18  ? 374  LEU D C     1 
ATOM   12783 O O     . LEU D 1 374 ? -16.975  -89.013  24.617  1.00 28.00  ? 374  LEU D O     1 
ATOM   12784 C CB    . LEU D 1 374 ? -19.064  -86.725  24.731  1.00 24.12  ? 374  LEU D CB    1 
ATOM   12785 C CG    . LEU D 1 374 ? -19.638  -85.624  25.631  1.00 26.24  ? 374  LEU D CG    1 
ATOM   12786 C CD1   . LEU D 1 374 ? -21.156  -85.866  25.766  1.00 20.84  ? 374  LEU D CD1   1 
ATOM   12787 C CD2   . LEU D 1 374 ? -18.933  -85.671  27.004  1.00 23.06  ? 374  LEU D CD2   1 
ATOM   12788 N N     . ASP D 1 375 ? -16.962  -88.061  22.593  1.00 22.72  ? 375  ASP D N     1 
ATOM   12789 C CA    . ASP D 1 375 ? -16.724  -89.358  21.956  1.00 22.48  ? 375  ASP D CA    1 
ATOM   12790 C C     . ASP D 1 375 ? -15.315  -89.895  22.232  1.00 26.30  ? 375  ASP D C     1 
ATOM   12791 O O     . ASP D 1 375 ? -15.115  -91.105  22.194  1.00 24.32  ? 375  ASP D O     1 
ATOM   12792 C CB    . ASP D 1 375 ? -16.946  -89.328  20.453  1.00 21.87  ? 375  ASP D CB    1 
ATOM   12793 C CG    . ASP D 1 375 ? -16.204  -88.192  19.759  1.00 24.58  ? 375  ASP D CG    1 
ATOM   12794 O OD1   . ASP D 1 375 ? -16.659  -87.018  19.897  1.00 28.41  ? 375  ASP D OD1   1 
ATOM   12795 O OD2   . ASP D 1 375 ? -15.139  -88.464  19.156  1.00 26.96  ? 375  ASP D OD2   1 
ATOM   12796 N N     . ASN D 1 376 ? -14.302  -89.030  22.438  1.00 25.63  ? 376  ASN D N     1 
ATOM   12797 C CA    . ASN D 1 376 ? -12.945  -89.555  22.523  1.00 23.43  ? 376  ASN D CA    1 
ATOM   12798 C C     . ASN D 1 376 ? -12.113  -88.786  23.545  1.00 27.49  ? 376  ASN D C     1 
ATOM   12799 O O     . ASN D 1 376 ? -10.909  -89.009  23.626  1.00 28.25  ? 376  ASN D O     1 
ATOM   12800 C CB    . ASN D 1 376 ? -12.228  -89.578  21.172  1.00 23.20  ? 376  ASN D CB    1 
ATOM   12801 C CG    . ASN D 1 376 ? -11.930  -88.190  20.642  1.00 26.22  ? 376  ASN D CG    1 
ATOM   12802 O OD1   . ASN D 1 376 ? -12.367  -87.176  21.216  1.00 21.63  ? 376  ASN D OD1   1 
ATOM   12803 N ND2   . ASN D 1 376 ? -11.201  -88.118  19.535  1.00 26.79  ? 376  ASN D ND2   1 
ATOM   12804 N N     . ASP D 1 377 ? -12.709  -87.819  24.262  1.00 27.52  ? 377  ASP D N     1 
ATOM   12805 C CA    . ASP D 1 377 ? -11.988  -87.067  25.289  1.00 26.64  ? 377  ASP D CA    1 
ATOM   12806 C C     . ASP D 1 377 ? -10.909  -86.129  24.754  1.00 26.11  ? 377  ASP D C     1 
ATOM   12807 O O     . ASP D 1 377 ? -10.156  -85.599  25.547  1.00 26.23  ? 377  ASP D O     1 
ATOM   12808 C CB    . ASP D 1 377 ? -11.458  -87.936  26.416  1.00 31.68  ? 377  ASP D CB    1 
ATOM   12809 C CG    . ASP D 1 377 ? -12.548  -88.594  27.263  1.00 47.44  ? 377  ASP D CG    1 
ATOM   12810 O OD1   . ASP D 1 377 ? -13.559  -87.926  27.608  1.00 55.23  ? 377  ASP D OD1   1 
ATOM   12811 O OD2   . ASP D 1 377 ? -12.377  -89.773  27.574  1.00 50.53  ? 377  ASP D OD2   1 
ATOM   12812 N N     . GLU D 1 378 ? -10.836  -85.876  23.441  1.00 25.18  ? 378  GLU D N     1 
ATOM   12813 C CA    . GLU D 1 378 ? -9.870   -84.899  22.956  1.00 24.38  ? 378  GLU D CA    1 
ATOM   12814 C C     . GLU D 1 378 ? -10.175  -83.521  23.552  1.00 27.13  ? 378  GLU D C     1 
ATOM   12815 O O     . GLU D 1 378 ? -11.326  -83.103  23.580  1.00 26.42  ? 378  GLU D O     1 
ATOM   12816 C CB    . GLU D 1 378 ? -9.841   -84.905  21.438  1.00 23.94  ? 378  GLU D CB    1 
ATOM   12817 C CG    . GLU D 1 378 ? -8.857   -83.893  20.869  1.00 29.58  ? 378  GLU D CG    1 
ATOM   12818 C CD    . GLU D 1 378 ? -9.043   -83.608  19.383  1.00 38.63  ? 378  GLU D CD    1 
ATOM   12819 O OE1   . GLU D 1 378 ? -10.036  -84.090  18.790  1.00 40.96  ? 378  GLU D OE1   1 
ATOM   12820 O OE2   . GLU D 1 378 ? -8.205   -82.874  18.816  1.00 40.45  ? 378  GLU D OE2   1 
ATOM   12821 N N     . VAL D 1 379 ? -9.138   -82.833  24.047  1.00 27.94  ? 379  VAL D N     1 
ATOM   12822 C CA    . VAL D 1 379 ? -9.260   -81.495  24.603  1.00 25.24  ? 379  VAL D CA    1 
ATOM   12823 C C     . VAL D 1 379 ? -9.224   -80.479  23.465  1.00 26.43  ? 379  VAL D C     1 
ATOM   12824 O O     . VAL D 1 379 ? -8.365   -80.574  22.590  1.00 27.18  ? 379  VAL D O     1 
ATOM   12825 C CB    . VAL D 1 379 ? -8.074   -81.273  25.566  1.00 28.75  ? 379  VAL D CB    1 
ATOM   12826 C CG1   . VAL D 1 379 ? -7.949   -79.818  26.002  1.00 23.12  ? 379  VAL D CG1   1 
ATOM   12827 C CG2   . VAL D 1 379 ? -8.174   -82.184  26.793  1.00 27.07  ? 379  VAL D CG2   1 
ATOM   12828 N N     . LEU D 1 380 ? -10.143  -79.505  23.491  1.00 22.55  ? 380  LEU D N     1 
ATOM   12829 C CA    . LEU D 1 380 ? -10.251  -78.526  22.421  1.00 23.78  ? 380  LEU D CA    1 
ATOM   12830 C C     . LEU D 1 380 ? -9.573   -77.228  22.844  1.00 26.77  ? 380  LEU D C     1 
ATOM   12831 O O     . LEU D 1 380 ? -9.674   -76.811  24.005  1.00 25.31  ? 380  LEU D O     1 
ATOM   12832 C CB    . LEU D 1 380 ? -11.724  -78.250  22.106  1.00 26.22  ? 380  LEU D CB    1 
ATOM   12833 C CG    . LEU D 1 380 ? -12.622  -79.453  21.773  1.00 29.69  ? 380  LEU D CG    1 
ATOM   12834 C CD1   . LEU D 1 380 ? -13.860  -78.955  21.087  1.00 28.46  ? 380  LEU D CD1   1 
ATOM   12835 C CD2   . LEU D 1 380 ? -11.822  -80.282  20.797  1.00 40.67  ? 380  LEU D CD2   1 
ATOM   12836 N N     . SER D 1 381 ? -8.934   -76.535  21.900  1.00 22.65  ? 381  SER D N     1 
ATOM   12837 C CA    . SER D 1 381 ? -8.482   -75.203  22.261  1.00 23.40  ? 381  SER D CA    1 
ATOM   12838 C C     . SER D 1 381 ? -9.624   -74.191  22.079  1.00 25.07  ? 381  SER D C     1 
ATOM   12839 O O     . SER D 1 381 ? -10.550  -74.422  21.300  1.00 24.35  ? 381  SER D O     1 
ATOM   12840 C CB    . SER D 1 381 ? -7.247   -74.852  21.483  1.00 24.54  ? 381  SER D CB    1 
ATOM   12841 O OG    . SER D 1 381 ? -7.512   -74.913  20.095  1.00 31.77  ? 381  SER D OG    1 
ATOM   12842 N N     . PHE D 1 382 ? -9.587   -73.086  22.834  1.00 22.17  ? 382  PHE D N     1 
ATOM   12843 C CA    . PHE D 1 382 ? -10.659  -72.113  22.816  1.00 22.14  ? 382  PHE D CA    1 
ATOM   12844 C C     . PHE D 1 382 ? -10.121  -70.742  23.244  1.00 25.97  ? 382  PHE D C     1 
ATOM   12845 O O     . PHE D 1 382 ? -9.054   -70.655  23.842  1.00 27.31  ? 382  PHE D O     1 
ATOM   12846 C CB    . PHE D 1 382 ? -11.782  -72.610  23.744  1.00 24.29  ? 382  PHE D CB    1 
ATOM   12847 C CG    . PHE D 1 382 ? -11.417  -72.612  25.220  1.00 22.41  ? 382  PHE D CG    1 
ATOM   12848 C CD1   . PHE D 1 382 ? -11.612  -71.464  26.001  1.00 25.30  ? 382  PHE D CD1   1 
ATOM   12849 C CD2   . PHE D 1 382 ? -10.830  -73.728  25.809  1.00 21.06  ? 382  PHE D CD2   1 
ATOM   12850 C CE1   . PHE D 1 382 ? -11.204  -71.426  27.339  1.00 23.35  ? 382  PHE D CE1   1 
ATOM   12851 C CE2   . PHE D 1 382 ? -10.466  -73.724  27.157  1.00 24.21  ? 382  PHE D CE2   1 
ATOM   12852 C CZ    . PHE D 1 382 ? -10.642  -72.561  27.919  1.00 24.05  ? 382  PHE D CZ    1 
ATOM   12853 N N     . THR D 1 383 ? -10.861  -69.676  22.929  1.00 23.99  ? 383  THR D N     1 
ATOM   12854 C CA    . THR D 1 383 ? -10.603  -68.328  23.406  1.00 25.92  ? 383  THR D CA    1 
ATOM   12855 C C     . THR D 1 383 ? -11.941  -67.770  23.879  1.00 25.68  ? 383  THR D C     1 
ATOM   12856 O O     . THR D 1 383 ? -13.004  -68.189  23.382  1.00 29.90  ? 383  THR D O     1 
ATOM   12857 C CB    . THR D 1 383 ? -10.046  -67.411  22.298  1.00 28.90  ? 383  THR D CB    1 
ATOM   12858 O OG1   . THR D 1 383 ? -11.038  -67.358  21.259  1.00 28.82  ? 383  THR D OG1   1 
ATOM   12859 C CG2   . THR D 1 383 ? -8.741   -67.884  21.688  1.00 27.71  ? 383  THR D CG2   1 
ATOM   12860 N N     . GLN D 1 384 ? -11.879  -66.835  24.831  1.00 24.21  ? 384  GLN D N     1 
ATOM   12861 C CA    . GLN D 1 384 ? -13.088  -66.206  25.327  1.00 24.36  ? 384  GLN D CA    1 
ATOM   12862 C C     . GLN D 1 384 ? -12.913  -64.699  25.312  1.00 26.04  ? 384  GLN D C     1 
ATOM   12863 O O     . GLN D 1 384 ? -11.833  -64.201  25.577  1.00 25.06  ? 384  GLN D O     1 
ATOM   12864 C CB    . GLN D 1 384 ? -13.403  -66.599  26.762  1.00 23.03  ? 384  GLN D CB    1 
ATOM   12865 C CG    . GLN D 1 384 ? -13.638  -68.088  26.933  1.00 24.78  ? 384  GLN D CG    1 
ATOM   12866 C CD    . GLN D 1 384 ? -14.112  -68.439  28.333  1.00 25.91  ? 384  GLN D CD    1 
ATOM   12867 O OE1   . GLN D 1 384 ? -13.318  -68.859  29.184  1.00 26.98  ? 384  GLN D OE1   1 
ATOM   12868 N NE2   . GLN D 1 384 ? -15.409  -68.296  28.573  1.00 19.00  ? 384  GLN D NE2   1 
ATOM   12869 N N     . ASP D 1 385 ? -14.011  -63.987  25.045  1.00 30.65  ? 385  ASP D N     1 
ATOM   12870 C CA    . ASP D 1 385 ? -14.155  -62.587  25.412  1.00 31.38  ? 385  ASP D CA    1 
ATOM   12871 C C     . ASP D 1 385 ? -15.300  -62.506  26.416  1.00 33.90  ? 385  ASP D C     1 
ATOM   12872 O O     . ASP D 1 385 ? -16.479  -62.569  26.032  1.00 30.29  ? 385  ASP D O     1 
ATOM   12873 C CB    . ASP D 1 385 ? -14.376  -61.715  24.189  1.00 35.26  ? 385  ASP D CB    1 
ATOM   12874 C CG    . ASP D 1 385 ? -14.738  -60.258  24.454  1.00 40.70  ? 385  ASP D CG    1 
ATOM   12875 O OD1   . ASP D 1 385 ? -15.070  -59.941  25.619  1.00 41.55  ? 385  ASP D OD1   1 
ATOM   12876 O OD2   . ASP D 1 385 ? -14.681  -59.453  23.478  1.00 41.13  ? 385  ASP D OD2   1 
ATOM   12877 N N     . LEU D 1 386 ? -14.928  -62.391  27.703  1.00 32.16  ? 386  LEU D N     1 
ATOM   12878 C CA    . LEU D 1 386 ? -15.914  -62.473  28.774  1.00 29.58  ? 386  LEU D CA    1 
ATOM   12879 C C     . LEU D 1 386 ? -16.846  -61.268  28.760  1.00 30.99  ? 386  LEU D C     1 
ATOM   12880 O O     . LEU D 1 386 ? -18.014  -61.414  29.089  1.00 32.34  ? 386  LEU D O     1 
ATOM   12881 C CB    . LEU D 1 386 ? -15.268  -62.690  30.131  1.00 27.18  ? 386  LEU D CB    1 
ATOM   12882 C CG    . LEU D 1 386 ? -14.373  -63.930  30.228  1.00 32.18  ? 386  LEU D CG    1 
ATOM   12883 C CD1   . LEU D 1 386 ? -13.482  -63.834  31.497  1.00 29.42  ? 386  LEU D CD1   1 
ATOM   12884 C CD2   . LEU D 1 386 ? -15.289  -65.184  30.205  1.00 28.51  ? 386  LEU D CD2   1 
ATOM   12885 N N     . ASP D 1 387 ? -16.373  -60.092  28.315  1.00 30.00  ? 387  ASP D N     1 
ATOM   12886 C CA    . ASP D 1 387 ? -17.248  -58.925  28.312  1.00 35.37  ? 387  ASP D CA    1 
ATOM   12887 C C     . ASP D 1 387 ? -18.384  -59.091  27.314  1.00 33.83  ? 387  ASP D C     1 
ATOM   12888 O O     . ASP D 1 387 ? -19.498  -58.699  27.600  1.00 32.31  ? 387  ASP D O     1 
ATOM   12889 C CB    . ASP D 1 387 ? -16.497  -57.614  28.127  1.00 42.73  ? 387  ASP D CB    1 
ATOM   12890 C CG    . ASP D 1 387 ? -15.416  -57.401  29.179  1.00 59.71  ? 387  ASP D CG    1 
ATOM   12891 O OD1   . ASP D 1 387 ? -15.763  -57.479  30.380  1.00 60.62  ? 387  ASP D OD1   1 
ATOM   12892 O OD2   . ASP D 1 387 ? -14.227  -57.238  28.801  1.00 70.04  ? 387  ASP D OD2   1 
ATOM   12893 N N     . LYS D 1 388 ? -18.092  -59.643  26.134  1.00 31.86  ? 388  LYS D N     1 
ATOM   12894 C CA    . LYS D 1 388 ? -19.105  -59.757  25.092  1.00 28.27  ? 388  LYS D CA    1 
ATOM   12895 C C     . LYS D 1 388 ? -19.738  -61.153  25.136  1.00 31.36  ? 388  LYS D C     1 
ATOM   12896 O O     . LYS D 1 388 ? -20.686  -61.429  24.397  1.00 27.38  ? 388  LYS D O     1 
ATOM   12897 C CB    . LYS D 1 388 ? -18.482  -59.329  23.757  1.00 25.59  ? 388  LYS D CB    1 
ATOM   12898 C CG    . LYS D 1 388 ? -18.567  -57.818  23.662  1.00 28.00  ? 388  LYS D CG    1 
ATOM   12899 C CD    . LYS D 1 388 ? -18.028  -57.254  22.375  1.00 28.02  ? 388  LYS D CD    1 
ATOM   12900 C CE    . LYS D 1 388 ? -18.435  -55.817  22.244  1.00 26.30  ? 388  LYS D CE    1 
ATOM   12901 N NZ    . LYS D 1 388 ? -17.888  -55.396  20.949  1.00 26.33  ? 388  LYS D NZ    1 
ATOM   12902 N N     . LYS D 1 389 ? -19.212  -62.022  26.009  1.00 25.55  ? 389  LYS D N     1 
ATOM   12903 C CA    . LYS D 1 389 ? -19.753  -63.350  26.231  1.00 27.50  ? 389  LYS D CA    1 
ATOM   12904 C C     . LYS D 1 389 ? -19.556  -64.223  24.991  1.00 28.24  ? 389  LYS D C     1 
ATOM   12905 O O     . LYS D 1 389 ? -20.443  -64.991  24.614  1.00 29.59  ? 389  LYS D O     1 
ATOM   12906 C CB    . LYS D 1 389 ? -21.186  -63.307  26.762  1.00 29.40  ? 389  LYS D CB    1 
ATOM   12907 C CG    . LYS D 1 389 ? -21.407  -62.502  28.032  1.00 37.04  ? 389  LYS D CG    1 
ATOM   12908 C CD    . LYS D 1 389 ? -22.894  -62.543  28.361  1.00 49.34  ? 389  LYS D CD    1 
ATOM   12909 C CE    . LYS D 1 389 ? -23.322  -61.678  29.500  1.00 53.43  ? 389  LYS D CE    1 
ATOM   12910 N NZ    . LYS D 1 389 ? -23.252  -62.578  30.644  1.00 66.52  ? 389  LYS D NZ    1 
ATOM   12911 N N     . VAL D 1 390 ? -18.359  -64.140  24.404  1.00 25.12  ? 390  VAL D N     1 
ATOM   12912 C CA    . VAL D 1 390 ? -18.026  -64.892  23.204  1.00 24.40  ? 390  VAL D CA    1 
ATOM   12913 C C     . VAL D 1 390 ? -17.109  -66.048  23.583  1.00 23.82  ? 390  VAL D C     1 
ATOM   12914 O O     . VAL D 1 390 ? -16.130  -65.853  24.305  1.00 20.40  ? 390  VAL D O     1 
ATOM   12915 C CB    . VAL D 1 390 ? -17.368  -64.021  22.119  1.00 22.12  ? 390  VAL D CB    1 
ATOM   12916 C CG1   . VAL D 1 390 ? -17.002  -64.854  20.905  1.00 21.08  ? 390  VAL D CG1   1 
ATOM   12917 C CG2   . VAL D 1 390 ? -18.282  -62.869  21.696  1.00 23.08  ? 390  VAL D CG2   1 
ATOM   12918 N N     . LEU D 1 391 ? -17.459  -67.241  23.080  1.00 22.56  ? 391  LEU D N     1 
ATOM   12919 C CA    . LEU D 1 391 ? -16.605  -68.413  23.113  1.00 22.47  ? 391  LEU D CA    1 
ATOM   12920 C C     . LEU D 1 391 ? -16.327  -68.863  21.673  1.00 25.31  ? 391  LEU D C     1 
ATOM   12921 O O     . LEU D 1 391 ? -17.260  -68.976  20.863  1.00 24.07  ? 391  LEU D O     1 
ATOM   12922 C CB    . LEU D 1 391 ? -17.351  -69.489  23.896  1.00 20.23  ? 391  LEU D CB    1 
ATOM   12923 C CG    . LEU D 1 391 ? -16.707  -70.878  23.845  1.00 22.62  ? 391  LEU D CG    1 
ATOM   12924 C CD1   . LEU D 1 391 ? -15.312  -70.848  24.484  1.00 21.24  ? 391  LEU D CD1   1 
ATOM   12925 C CD2   . LEU D 1 391 ? -17.602  -71.965  24.486  1.00 22.05  ? 391  LEU D CD2   1 
ATOM   12926 N N     . THR D 1 392 ? -15.047  -69.134  21.365  1.00 21.81  ? 392  THR D N     1 
ATOM   12927 C CA    . THR D 1 392 ? -14.670  -69.698  20.079  1.00 20.93  ? 392  THR D CA    1 
ATOM   12928 C C     . THR D 1 392 ? -13.840  -70.945  20.345  1.00 21.96  ? 392  THR D C     1 
ATOM   12929 O O     . THR D 1 392 ? -12.843  -70.840  21.040  1.00 26.62  ? 392  THR D O     1 
ATOM   12930 C CB    . THR D 1 392 ? -13.846  -68.703  19.249  1.00 18.74  ? 392  THR D CB    1 
ATOM   12931 O OG1   . THR D 1 392 ? -14.612  -67.512  19.108  1.00 20.45  ? 392  THR D OG1   1 
ATOM   12932 C CG2   . THR D 1 392 ? -13.535  -69.250  17.861  1.00 17.02  ? 392  THR D CG2   1 
ATOM   12933 N N     . VAL D 1 393 ? -14.234  -72.097  19.787  1.00 21.61  ? 393  VAL D N     1 
ATOM   12934 C CA    . VAL D 1 393 ? -13.485  -73.334  19.937  1.00 21.86  ? 393  VAL D CA    1 
ATOM   12935 C C     . VAL D 1 393 ? -12.978  -73.747  18.562  1.00 21.78  ? 393  VAL D C     1 
ATOM   12936 O O     . VAL D 1 393 ? -13.604  -73.415  17.532  1.00 24.43  ? 393  VAL D O     1 
ATOM   12937 C CB    . VAL D 1 393 ? -14.313  -74.492  20.531  1.00 21.90  ? 393  VAL D CB    1 
ATOM   12938 C CG1   . VAL D 1 393 ? -15.009  -74.063  21.802  1.00 22.61  ? 393  VAL D CG1   1 
ATOM   12939 C CG2   . VAL D 1 393 ? -15.379  -74.942  19.536  1.00 24.78  ? 393  VAL D CG2   1 
ATOM   12940 N N     . ASP D 1 394 ? -11.850  -74.469  18.556  1.00 19.93  ? 394  ASP D N     1 
ATOM   12941 C CA    . ASP D 1 394 ? -11.418  -75.111  17.319  1.00 25.02  ? 394  ASP D CA    1 
ATOM   12942 C C     . ASP D 1 394 ? -12.065  -76.497  17.311  1.00 27.25  ? 394  ASP D C     1 
ATOM   12943 O O     . ASP D 1 394 ? -11.595  -77.400  18.034  1.00 23.93  ? 394  ASP D O     1 
ATOM   12944 C CB    . ASP D 1 394 ? -9.904   -75.228  17.204  1.00 23.97  ? 394  ASP D CB    1 
ATOM   12945 C CG    . ASP D 1 394 ? -9.418   -76.117  16.059  1.00 29.40  ? 394  ASP D CG    1 
ATOM   12946 O OD1   . ASP D 1 394 ? -10.229  -76.370  15.094  1.00 26.51  ? 394  ASP D OD1   1 
ATOM   12947 O OD2   . ASP D 1 394 ? -8.233   -76.567  16.129  1.00 30.36  ? 394  ASP D OD2   1 
ATOM   12948 N N     . ALA D 1 395 ? -13.150  -76.643  16.534  1.00 24.68  ? 395  ALA D N     1 
ATOM   12949 C CA    . ALA D 1 395 ? -13.914  -77.884  16.553  1.00 23.49  ? 395  ALA D CA    1 
ATOM   12950 C C     . ALA D 1 395 ? -13.251  -78.860  15.581  1.00 23.14  ? 395  ALA D C     1 
ATOM   12951 O O     . ALA D 1 395 ? -13.543  -78.845  14.378  1.00 23.35  ? 395  ALA D O     1 
ATOM   12952 C CB    . ALA D 1 395 ? -15.383  -77.634  16.205  1.00 18.25  ? 395  ALA D CB    1 
ATOM   12953 N N     . THR D 1 396 ? -12.343  -79.699  16.103  1.00 21.38  ? 396  THR D N     1 
ATOM   12954 C CA    . THR D 1 396 ? -11.606  -80.614  15.249  1.00 22.11  ? 396  THR D CA    1 
ATOM   12955 C C     . THR D 1 396 ? -12.576  -81.617  14.605  1.00 23.10  ? 396  THR D C     1 
ATOM   12956 O O     . THR D 1 396 ? -13.632  -81.931  15.174  1.00 19.81  ? 396  THR D O     1 
ATOM   12957 C CB    . THR D 1 396 ? -10.488  -81.283  16.053  1.00 20.81  ? 396  THR D CB    1 
ATOM   12958 O OG1   . THR D 1 396 ? -11.109  -81.855  17.212  1.00 20.61  ? 396  THR D OG1   1 
ATOM   12959 C CG2   . THR D 1 396 ? -9.407   -80.289  16.453  1.00 19.19  ? 396  THR D CG2   1 
ATOM   12960 N N     . GLY D 1 397 ? -12.194  -82.128  13.426  1.00 18.81  ? 397  GLY D N     1 
ATOM   12961 C CA    . GLY D 1 397 ? -13.035  -83.040  12.684  1.00 18.80  ? 397  GLY D CA    1 
ATOM   12962 C C     . GLY D 1 397 ? -12.951  -84.448  13.284  1.00 23.42  ? 397  GLY D C     1 
ATOM   12963 O O     . GLY D 1 397 ? -12.211  -84.688  14.247  1.00 22.64  ? 397  GLY D O     1 
ATOM   12964 N N     . TYR D 1 398 ? -13.734  -85.381  12.721  1.00 21.69  ? 398  TYR D N     1 
ATOM   12965 C CA    . TYR D 1 398 ? -13.807  -86.713  13.285  1.00 25.28  ? 398  TYR D CA    1 
ATOM   12966 C C     . TYR D 1 398 ? -12.505  -87.464  13.033  1.00 27.11  ? 398  TYR D C     1 
ATOM   12967 O O     . TYR D 1 398 ? -11.934  -87.385  11.942  1.00 27.18  ? 398  TYR D O     1 
ATOM   12968 C CB    . TYR D 1 398 ? -14.961  -87.504  12.657  1.00 24.06  ? 398  TYR D CB    1 
ATOM   12969 C CG    . TYR D 1 398 ? -16.310  -86.845  12.875  1.00 22.47  ? 398  TYR D CG    1 
ATOM   12970 C CD1   . TYR D 1 398 ? -16.844  -86.773  14.167  1.00 22.62  ? 398  TYR D CD1   1 
ATOM   12971 C CD2   . TYR D 1 398 ? -17.046  -86.307  11.805  1.00 22.73  ? 398  TYR D CD2   1 
ATOM   12972 C CE1   . TYR D 1 398 ? -18.072  -86.179  14.402  1.00 21.53  ? 398  TYR D CE1   1 
ATOM   12973 C CE2   . TYR D 1 398 ? -18.289  -85.709  12.027  1.00 23.67  ? 398  TYR D CE2   1 
ATOM   12974 C CZ    . TYR D 1 398 ? -18.786  -85.655  13.332  1.00 24.37  ? 398  TYR D CZ    1 
ATOM   12975 O OH    . TYR D 1 398 ? -19.966  -85.072  13.650  1.00 29.82  ? 398  TYR D OH    1 
ATOM   12976 N N     . PRO D 1 399 ? -12.048  -88.297  13.997  1.00 26.22  ? 399  PRO D N     1 
ATOM   12977 C CA    . PRO D 1 399 ? -11.036  -89.300  13.684  1.00 24.25  ? 399  PRO D CA    1 
ATOM   12978 C C     . PRO D 1 399 ? -11.492  -90.173  12.516  1.00 23.54  ? 399  PRO D C     1 
ATOM   12979 O O     . PRO D 1 399 ? -12.652  -90.579  12.456  1.00 21.52  ? 399  PRO D O     1 
ATOM   12980 C CB    . PRO D 1 399 ? -10.926  -90.172  14.939  1.00 22.11  ? 399  PRO D CB    1 
ATOM   12981 C CG    . PRO D 1 399 ? -11.629  -89.378  16.003  1.00 22.84  ? 399  PRO D CG    1 
ATOM   12982 C CD    . PRO D 1 399 ? -12.555  -88.382  15.368  1.00 25.51  ? 399  PRO D CD    1 
ATOM   12983 N N     . TYR D 1 400 ? -10.580  -90.451  11.592  1.00 21.71  ? 400  TYR D N     1 
ATOM   12984 C CA    . TYR D 1 400 ? -10.893  -91.324  10.485  1.00 21.17  ? 400  TYR D CA    1 
ATOM   12985 C C     . TYR D 1 400 ? -11.534  -92.587  11.039  1.00 21.60  ? 400  TYR D C     1 
ATOM   12986 O O     . TYR D 1 400 ? -11.100  -93.113  12.076  1.00 20.39  ? 400  TYR D O     1 
ATOM   12987 C CB    . TYR D 1 400 ? -9.614   -91.598  9.677   1.00 21.20  ? 400  TYR D CB    1 
ATOM   12988 C CG    . TYR D 1 400 ? -9.873   -92.592  8.556   1.00 19.92  ? 400  TYR D CG    1 
ATOM   12989 C CD1   . TYR D 1 400 ? -10.508  -92.210  7.366   1.00 18.41  ? 400  TYR D CD1   1 
ATOM   12990 C CD2   . TYR D 1 400 ? -9.539   -93.932  8.732   1.00 17.73  ? 400  TYR D CD2   1 
ATOM   12991 C CE1   . TYR D 1 400 ? -10.804  -93.154  6.385   1.00 18.14  ? 400  TYR D CE1   1 
ATOM   12992 C CE2   . TYR D 1 400 ? -9.792   -94.856  7.732   1.00 18.90  ? 400  TYR D CE2   1 
ATOM   12993 C CZ    . TYR D 1 400 ? -10.453  -94.474  6.576   1.00 19.11  ? 400  TYR D CZ    1 
ATOM   12994 O OH    . TYR D 1 400 ? -10.685  -95.430  5.635   1.00 21.82  ? 400  TYR D OH    1 
ATOM   12995 N N     . GLY D 1 401 ? -12.588  -93.048  10.342  1.00 18.53  ? 401  GLY D N     1 
ATOM   12996 C CA    . GLY D 1 401 ? -13.257  -94.263  10.765  1.00 18.24  ? 401  GLY D CA    1 
ATOM   12997 C C     . GLY D 1 401 ? -14.453  -93.983  11.670  1.00 22.68  ? 401  GLY D C     1 
ATOM   12998 O O     . GLY D 1 401 ? -15.143  -94.906  12.104  1.00 20.44  ? 401  GLY D O     1 
ATOM   12999 N N     . SER D 1 402 ? -14.723  -92.702  11.955  1.00 22.68  ? 402  SER D N     1 
ATOM   13000 C CA    . SER D 1 402 ? -15.911  -92.431  12.746  1.00 25.21  ? 402  SER D CA    1 
ATOM   13001 C C     . SER D 1 402 ? -16.586  -91.145  12.257  1.00 24.44  ? 402  SER D C     1 
ATOM   13002 O O     . SER D 1 402 ? -15.992  -90.371  11.497  1.00 23.74  ? 402  SER D O     1 
ATOM   13003 C CB    . SER D 1 402 ? -15.591  -92.463  14.222  1.00 25.18  ? 402  SER D CB    1 
ATOM   13004 O OG    . SER D 1 402 ? -14.934  -91.247  14.522  1.00 38.92  ? 402  SER D OG    1 
ATOM   13005 N N     . ASP D 1 403 ? -17.868  -90.965  12.609  1.00 23.18  ? 403  ASP D N     1 
ATOM   13006 C CA    . ASP D 1 403 ? -18.647  -89.804  12.199  1.00 21.94  ? 403  ASP D CA    1 
ATOM   13007 C C     . ASP D 1 403 ? -19.951  -89.815  12.996  1.00 23.14  ? 403  ASP D C     1 
ATOM   13008 O O     . ASP D 1 403 ? -20.837  -90.651  12.741  1.00 24.85  ? 403  ASP D O     1 
ATOM   13009 C CB    . ASP D 1 403 ? -18.891  -89.788  10.695  1.00 22.15  ? 403  ASP D CB    1 
ATOM   13010 C CG    . ASP D 1 403 ? -19.595  -88.547  10.149  1.00 26.22  ? 403  ASP D CG    1 
ATOM   13011 O OD1   . ASP D 1 403 ? -20.317  -87.872  10.937  1.00 24.29  ? 403  ASP D OD1   1 
ATOM   13012 O OD2   . ASP D 1 403 ? -19.388  -88.225  8.935   1.00 27.93  ? 403  ASP D OD2   1 
ATOM   13013 N N     . TRP D 1 404 ? -20.068  -88.872  13.949  1.00 21.15  ? 404  TRP D N     1 
ATOM   13014 C CA    . TRP D 1 404 ? -21.140  -88.901  14.938  1.00 18.13  ? 404  TRP D CA    1 
ATOM   13015 C C     . TRP D 1 404 ? -22.345  -88.073  14.493  1.00 20.31  ? 404  TRP D C     1 
ATOM   13016 O O     . TRP D 1 404 ? -23.371  -88.060  15.183  1.00 21.73  ? 404  TRP D O     1 
ATOM   13017 C CB    . TRP D 1 404 ? -20.609  -88.441  16.304  1.00 17.90  ? 404  TRP D CB    1 
ATOM   13018 C CG    . TRP D 1 404 ? -19.618  -89.409  16.891  1.00 19.75  ? 404  TRP D CG    1 
ATOM   13019 C CD1   . TRP D 1 404 ? -18.256  -89.382  16.748  1.00 19.79  ? 404  TRP D CD1   1 
ATOM   13020 C CD2   . TRP D 1 404 ? -19.924  -90.603  17.658  1.00 19.44  ? 404  TRP D CD2   1 
ATOM   13021 N NE1   . TRP D 1 404 ? -17.692  -90.481  17.352  1.00 20.25  ? 404  TRP D NE1   1 
ATOM   13022 C CE2   . TRP D 1 404 ? -18.682  -91.244  17.923  1.00 19.43  ? 404  TRP D CE2   1 
ATOM   13023 C CE3   . TRP D 1 404 ? -21.104  -91.194  18.131  1.00 17.48  ? 404  TRP D CE3   1 
ATOM   13024 C CZ2   . TRP D 1 404 ? -18.593  -92.428  18.647  1.00 18.01  ? 404  TRP D CZ2   1 
ATOM   13025 C CZ3   . TRP D 1 404 ? -21.020  -92.374  18.846  1.00 21.08  ? 404  TRP D CZ3   1 
ATOM   13026 C CH2   . TRP D 1 404 ? -19.773  -92.978  19.104  1.00 20.57  ? 404  TRP D CH2   1 
ATOM   13027 N N     . VAL D 1 405 ? -22.211  -87.339  13.369  1.00 18.13  ? 405  VAL D N     1 
ATOM   13028 C CA    . VAL D 1 405 ? -23.293  -86.510  12.846  1.00 18.20  ? 405  VAL D CA    1 
ATOM   13029 C C     . VAL D 1 405 ? -23.522  -85.267  13.715  1.00 17.92  ? 405  VAL D C     1 
ATOM   13030 O O     . VAL D 1 405 ? -23.454  -84.149  13.205  1.00 18.52  ? 405  VAL D O     1 
ATOM   13031 C CB    . VAL D 1 405 ? -24.618  -87.250  12.573  1.00 16.05  ? 405  VAL D CB    1 
ATOM   13032 C CG1   . VAL D 1 405 ? -25.650  -86.306  11.977  1.00 14.94  ? 405  VAL D CG1   1 
ATOM   13033 C CG2   . VAL D 1 405 ? -24.371  -88.459  11.663  1.00 15.32  ? 405  VAL D CG2   1 
ATOM   13034 N N     . VAL D 1 406 ? -23.893  -85.456  14.988  1.00 17.25  ? 406  VAL D N     1 
ATOM   13035 C CA    . VAL D 1 406 ? -23.916  -84.347  15.939  1.00 17.21  ? 406  VAL D CA    1 
ATOM   13036 C C     . VAL D 1 406 ? -22.847  -84.657  16.990  1.00 19.84  ? 406  VAL D C     1 
ATOM   13037 O O     . VAL D 1 406 ? -22.973  -85.639  17.719  1.00 20.64  ? 406  VAL D O     1 
ATOM   13038 C CB    . VAL D 1 406 ? -25.295  -84.173  16.613  1.00 15.15  ? 406  VAL D CB    1 
ATOM   13039 C CG1   . VAL D 1 406 ? -25.268  -83.095  17.710  1.00 12.44  ? 406  VAL D CG1   1 
ATOM   13040 C CG2   . VAL D 1 406 ? -26.404  -83.876  15.598  1.00 13.79  ? 406  VAL D CG2   1 
ATOM   13041 N N     . ARG D 1 407 ? -21.783  -83.851  17.043  1.00 19.77  ? 407  ARG D N     1 
ATOM   13042 C CA    . ARG D 1 407 ? -20.678  -84.106  17.966  1.00 18.38  ? 407  ARG D CA    1 
ATOM   13043 C C     . ARG D 1 407 ? -20.851  -83.213  19.193  1.00 19.23  ? 407  ARG D C     1 
ATOM   13044 O O     . ARG D 1 407 ? -21.330  -82.079  19.072  1.00 18.70  ? 407  ARG D O     1 
ATOM   13045 C CB    . ARG D 1 407 ? -19.336  -83.834  17.272  1.00 17.93  ? 407  ARG D CB    1 
ATOM   13046 C CG    . ARG D 1 407 ? -18.207  -84.683  17.853  1.00 19.08  ? 407  ARG D CG    1 
ATOM   13047 C CD    . ARG D 1 407 ? -16.853  -84.313  17.267  1.00 20.56  ? 407  ARG D CD    1 
ATOM   13048 N NE    . ARG D 1 407 ? -15.896  -85.291  17.792  1.00 18.27  ? 407  ARG D NE    1 
ATOM   13049 C CZ    . ARG D 1 407 ? -14.605  -85.359  17.408  1.00 18.97  ? 407  ARG D CZ    1 
ATOM   13050 N NH1   . ARG D 1 407 ? -14.101  -84.451  16.527  1.00 14.97  ? 407  ARG D NH1   1 
ATOM   13051 N NH2   . ARG D 1 407 ? -13.855  -86.326  17.933  1.00 14.85  ? 407  ARG D NH2   1 
ATOM   13052 N N     . ILE D 1 408 ? -20.498  -83.730  20.384  1.00 20.03  ? 408  ILE D N     1 
ATOM   13053 C CA    . ILE D 1 408 ? -20.823  -82.998  21.605  1.00 21.36  ? 408  ILE D CA    1 
ATOM   13054 C C     . ILE D 1 408 ? -19.557  -82.743  22.415  1.00 21.08  ? 408  ILE D C     1 
ATOM   13055 O O     . ILE D 1 408 ? -18.821  -83.680  22.732  1.00 23.56  ? 408  ILE D O     1 
ATOM   13056 C CB    . ILE D 1 408 ? -21.875  -83.757  22.444  1.00 21.27  ? 408  ILE D CB    1 
ATOM   13057 C CG1   . ILE D 1 408 ? -23.134  -84.110  21.601  1.00 19.92  ? 408  ILE D CG1   1 
ATOM   13058 C CG2   . ILE D 1 408 ? -22.175  -82.992  23.737  1.00 17.87  ? 408  ILE D CG2   1 
ATOM   13059 C CD1   . ILE D 1 408 ? -24.192  -84.877  22.349  1.00 17.90  ? 408  ILE D CD1   1 
ATOM   13060 N N     . ALA D 1 409 ? -19.316  -81.478  22.757  1.00 19.32  ? 409  ALA D N     1 
ATOM   13061 C CA    . ALA D 1 409 ? -18.172  -81.095  23.579  1.00 20.97  ? 409  ALA D CA    1 
ATOM   13062 C C     . ALA D 1 409 ? -18.691  -80.640  24.942  1.00 22.96  ? 409  ALA D C     1 
ATOM   13063 O O     . ALA D 1 409 ? -19.606  -79.799  25.018  1.00 23.05  ? 409  ALA D O     1 
ATOM   13064 C CB    . ALA D 1 409 ? -17.375  -79.965  22.904  1.00 20.36  ? 409  ALA D CB    1 
ATOM   13065 N N     . GLN D 1 410 ? -18.105  -81.197  26.005  1.00 21.62  ? 410  GLN D N     1 
ATOM   13066 C CA    . GLN D 1 410 ? -18.446  -80.803  27.362  1.00 22.56  ? 410  GLN D CA    1 
ATOM   13067 C C     . GLN D 1 410 ? -17.530  -79.662  27.825  1.00 26.19  ? 410  GLN D C     1 
ATOM   13068 O O     . GLN D 1 410 ? -16.307  -79.728  27.682  1.00 27.71  ? 410  GLN D O     1 
ATOM   13069 C CB    . GLN D 1 410 ? -18.211  -81.968  28.311  1.00 22.37  ? 410  GLN D CB    1 
ATOM   13070 C CG    . GLN D 1 410 ? -18.647  -81.672  29.740  1.00 23.11  ? 410  GLN D CG    1 
ATOM   13071 C CD    . GLN D 1 410 ? -18.523  -82.893  30.621  1.00 27.51  ? 410  GLN D CD    1 
ATOM   13072 O OE1   . GLN D 1 410 ? -19.134  -83.940  30.365  1.00 31.18  ? 410  GLN D OE1   1 
ATOM   13073 N NE2   . GLN D 1 410 ? -17.681  -82.794  31.643  1.00 23.70  ? 410  GLN D NE2   1 
ATOM   13074 N N     . ILE D 1 411 ? -18.150  -78.616  28.378  1.00 23.63  ? 411  ILE D N     1 
ATOM   13075 C CA    . ILE D 1 411 ? -17.451  -77.504  28.990  1.00 22.59  ? 411  ILE D CA    1 
ATOM   13076 C C     . ILE D 1 411 ? -17.354  -77.735  30.509  1.00 25.56  ? 411  ILE D C     1 
ATOM   13077 O O     . ILE D 1 411 ? -18.373  -77.929  31.180  1.00 25.45  ? 411  ILE D O     1 
ATOM   13078 C CB    . ILE D 1 411 ? -18.206  -76.197  28.699  1.00 19.19  ? 411  ILE D CB    1 
ATOM   13079 C CG1   . ILE D 1 411 ? -18.188  -75.854  27.203  1.00 18.39  ? 411  ILE D CG1   1 
ATOM   13080 C CG2   . ILE D 1 411 ? -17.592  -75.072  29.515  1.00 19.37  ? 411  ILE D CG2   1 
ATOM   13081 C CD1   . ILE D 1 411 ? -19.084  -74.692  26.794  1.00 17.12  ? 411  ILE D CD1   1 
ATOM   13082 N N     . ASP D 1 412 ? -16.123  -77.671  31.043  1.00 26.33  ? 412  ASP D N     1 
ATOM   13083 C CA    . ASP D 1 412 ? -15.848  -77.641  32.486  1.00 27.37  ? 412  ASP D CA    1 
ATOM   13084 C C     . ASP D 1 412 ? -15.459  -76.221  32.875  1.00 27.25  ? 412  ASP D C     1 
ATOM   13085 O O     . ASP D 1 412 ? -14.466  -75.685  32.377  1.00 26.83  ? 412  ASP D O     1 
ATOM   13086 C CB    . ASP D 1 412 ? -14.733  -78.610  32.846  1.00 26.24  ? 412  ASP D CB    1 
ATOM   13087 C CG    . ASP D 1 412 ? -15.029  -80.068  32.503  1.00 32.49  ? 412  ASP D CG    1 
ATOM   13088 O OD1   . ASP D 1 412 ? -16.225  -80.392  32.313  1.00 35.44  ? 412  ASP D OD1   1 
ATOM   13089 O OD2   . ASP D 1 412 ? -14.076  -80.880  32.381  1.00 41.30  ? 412  ASP D OD2   1 
ATOM   13090 N N     . TYR D 1 413 ? -16.266  -75.602  33.730  1.00 28.20  ? 413  TYR D N     1 
ATOM   13091 C CA    . TYR D 1 413 ? -15.996  -74.252  34.211  1.00 32.55  ? 413  TYR D CA    1 
ATOM   13092 C C     . TYR D 1 413 ? -14.953  -74.253  35.332  1.00 36.18  ? 413  TYR D C     1 
ATOM   13093 O O     . TYR D 1 413 ? -14.802  -75.225  36.065  1.00 34.35  ? 413  TYR D O     1 
ATOM   13094 C CB    . TYR D 1 413 ? -17.284  -73.612  34.728  1.00 28.16  ? 413  TYR D CB    1 
ATOM   13095 C CG    . TYR D 1 413 ? -18.160  -73.256  33.545  1.00 31.75  ? 413  TYR D CG    1 
ATOM   13096 C CD1   . TYR D 1 413 ? -17.830  -72.180  32.717  1.00 30.99  ? 413  TYR D CD1   1 
ATOM   13097 C CD2   . TYR D 1 413 ? -19.276  -74.033  33.211  1.00 28.75  ? 413  TYR D CD2   1 
ATOM   13098 C CE1   . TYR D 1 413 ? -18.614  -71.864  31.615  1.00 32.23  ? 413  TYR D CE1   1 
ATOM   13099 C CE2   . TYR D 1 413 ? -20.070  -73.712  32.115  1.00 28.64  ? 413  TYR D CE2   1 
ATOM   13100 C CZ    . TYR D 1 413 ? -19.724  -72.644  31.305  1.00 29.38  ? 413  TYR D CZ    1 
ATOM   13101 O OH    . TYR D 1 413 ? -20.517  -72.332  30.251  1.00 28.43  ? 413  TYR D OH    1 
ATOM   13102 N N     . GLU D 1 414 ? -14.228  -73.138  35.425  1.00 47.39  ? 414  GLU D N     1 
ATOM   13103 C CA    . GLU D 1 414 ? -13.350  -72.834  36.545  1.00 62.56  ? 414  GLU D CA    1 
ATOM   13104 C C     . GLU D 1 414 ? -14.185  -72.646  37.824  1.00 63.29  ? 414  GLU D C     1 
ATOM   13105 O O     . GLU D 1 414 ? -15.186  -71.884  37.759  1.00 60.83  ? 414  GLU D O     1 
ATOM   13106 C CB    . GLU D 1 414 ? -12.471  -71.608  36.308  1.00 58.79  ? 414  GLU D CB    1 
ATOM   13107 C CG    . GLU D 1 414 ? -11.344  -71.921  35.338  1.00 75.85  ? 414  GLU D CG    1 
ATOM   13108 C CD    . GLU D 1 414 ? -10.168  -70.970  35.324  1.00 89.83  ? 414  GLU D CD    1 
ATOM   13109 O OE1   . GLU D 1 414 ? -10.338  -69.737  35.546  1.00 84.22  ? 414  GLU D OE1   1 
ATOM   13110 O OE2   . GLU D 1 414 ? -9.073   -71.520  35.042  1.00 91.66  ? 414  GLU D OE2   1 
ATOM   13111 O OXT   . GLU D 1 414 ? -13.804  -73.281  38.829  1.00 65.46  ? 414  GLU D OXT   1 
ATOM   13112 N N     . THR E 1 2   ? -69.972  21.380   -59.763 1.00 72.71  ? 2    THR E N     1 
ATOM   13113 C CA    . THR E 1 2   ? -68.661  22.066   -59.686 1.00 90.66  ? 2    THR E CA    1 
ATOM   13114 C C     . THR E 1 2   ? -67.568  21.023   -59.492 1.00 93.26  ? 2    THR E C     1 
ATOM   13115 O O     . THR E 1 2   ? -67.836  19.895   -59.091 1.00 83.74  ? 2    THR E O     1 
ATOM   13116 C CB    . THR E 1 2   ? -68.577  23.118   -58.577 1.00 85.31  ? 2    THR E CB    1 
ATOM   13117 O OG1   . THR E 1 2   ? -68.870  22.416   -57.373 1.00 89.50  ? 2    THR E OG1   1 
ATOM   13118 C CG2   . THR E 1 2   ? -69.438  24.339   -58.850 1.00 83.34  ? 2    THR E CG2   1 
ATOM   13119 N N     . GLU E 1 3   ? -66.340  21.446   -59.795 1.00 87.26  ? 3    GLU E N     1 
ATOM   13120 C CA    . GLU E 1 3   ? -65.192  20.557   -59.830 1.00 84.44  ? 3    GLU E CA    1 
ATOM   13121 C C     . GLU E 1 3   ? -64.482  20.621   -58.476 1.00 79.69  ? 3    GLU E C     1 
ATOM   13122 O O     . GLU E 1 3   ? -64.376  21.685   -57.866 1.00 66.72  ? 3    GLU E O     1 
ATOM   13123 C CB    . GLU E 1 3   ? -64.448  21.026   -61.081 1.00 80.91  ? 3    GLU E CB    1 
ATOM   13124 C CG    . GLU E 1 3   ? -63.025  20.509   -61.235 1.00 89.54  ? 3    GLU E CG    1 
ATOM   13125 C CD    . GLU E 1 3   ? -62.867  19.246   -62.064 1.00 109.00 ? 3    GLU E CD    1 
ATOM   13126 O OE1   . GLU E 1 3   ? -63.854  18.542   -62.410 1.00 99.25  ? 3    GLU E OE1   1 
ATOM   13127 O OE2   . GLU E 1 3   ? -61.688  18.987   -62.376 1.00 103.26 ? 3    GLU E OE2   1 
ATOM   13128 N N     . PRO E 1 4   ? -64.059  19.471   -57.906 1.00 71.90  ? 4    PRO E N     1 
ATOM   13129 C CA    . PRO E 1 4   ? -63.296  19.490   -56.663 1.00 68.26  ? 4    PRO E CA    1 
ATOM   13130 C C     . PRO E 1 4   ? -62.017  20.315   -56.764 1.00 52.99  ? 4    PRO E C     1 
ATOM   13131 O O     . PRO E 1 4   ? -61.315  20.218   -57.765 1.00 48.85  ? 4    PRO E O     1 
ATOM   13132 C CB    . PRO E 1 4   ? -62.982  18.016   -56.381 1.00 66.01  ? 4    PRO E CB    1 
ATOM   13133 C CG    . PRO E 1 4   ? -63.370  17.289   -57.663 1.00 61.40  ? 4    PRO E CG    1 
ATOM   13134 C CD    . PRO E 1 4   ? -64.379  18.119   -58.384 1.00 65.34  ? 4    PRO E CD    1 
ATOM   13135 N N     . LEU E 1 5   ? -61.708  21.085   -55.713 1.00 49.91  ? 5    LEU E N     1 
ATOM   13136 C CA    . LEU E 1 5   ? -60.398  21.710   -55.582 1.00 47.07  ? 5    LEU E CA    1 
ATOM   13137 C C     . LEU E 1 5   ? -59.305  20.657   -55.741 1.00 46.83  ? 5    LEU E C     1 
ATOM   13138 O O     . LEU E 1 5   ? -59.500  19.498   -55.370 1.00 47.12  ? 5    LEU E O     1 
ATOM   13139 C CB    . LEU E 1 5   ? -60.296  22.398   -54.222 1.00 47.96  ? 5    LEU E CB    1 
ATOM   13140 C CG    . LEU E 1 5   ? -61.218  23.608   -54.012 1.00 53.86  ? 5    LEU E CG    1 
ATOM   13141 C CD1   . LEU E 1 5   ? -61.139  24.089   -52.566 1.00 45.97  ? 5    LEU E CD1   1 
ATOM   13142 C CD2   . LEU E 1 5   ? -60.826  24.720   -54.992 1.00 49.60  ? 5    LEU E CD2   1 
ATOM   13143 N N     . PRO E 1 6   ? -58.108  21.010   -56.268 1.00 46.43  ? 6    PRO E N     1 
ATOM   13144 C CA    . PRO E 1 6   ? -57.001  20.059   -56.334 1.00 46.53  ? 6    PRO E CA    1 
ATOM   13145 C C     . PRO E 1 6   ? -56.773  19.220   -55.069 1.00 48.82  ? 6    PRO E C     1 
ATOM   13146 O O     . PRO E 1 6   ? -56.509  18.023   -55.159 1.00 48.07  ? 6    PRO E O     1 
ATOM   13147 C CB    . PRO E 1 6   ? -55.797  20.890   -56.815 1.00 43.36  ? 6    PRO E CB    1 
ATOM   13148 C CG    . PRO E 1 6   ? -56.477  22.030   -57.573 1.00 42.64  ? 6    PRO E CG    1 
ATOM   13149 C CD    . PRO E 1 6   ? -57.796  22.303   -56.896 1.00 44.90  ? 6    PRO E CD    1 
ATOM   13150 N N     . ARG E 1 7   ? -56.829  19.848   -53.883 1.00 45.13  ? 7    ARG E N     1 
ATOM   13151 C CA    . ARG E 1 7   ? -56.441  19.132   -52.680 1.00 40.76  ? 7    ARG E CA    1 
ATOM   13152 C C     . ARG E 1 7   ? -57.494  18.053   -52.373 1.00 41.19  ? 7    ARG E C     1 
ATOM   13153 O O     . ARG E 1 7   ? -57.157  17.012   -51.809 1.00 34.68  ? 7    ARG E O     1 
ATOM   13154 C CB    . ARG E 1 7   ? -56.159  20.045   -51.478 1.00 33.75  ? 7    ARG E CB    1 
ATOM   13155 C CG    . ARG E 1 7   ? -57.384  20.735   -50.888 1.00 31.55  ? 7    ARG E CG    1 
ATOM   13156 C CD    . ARG E 1 7   ? -57.159  21.415   -49.529 1.00 32.41  ? 7    ARG E CD    1 
ATOM   13157 N NE    . ARG E 1 7   ? -58.389  22.106   -49.105 1.00 36.19  ? 7    ARG E NE    1 
ATOM   13158 C CZ    . ARG E 1 7   ? -58.814  23.267   -49.640 1.00 39.98  ? 7    ARG E CZ    1 
ATOM   13159 N NH1   . ARG E 1 7   ? -58.001  23.921   -50.469 1.00 33.16  ? 7    ARG E NH1   1 
ATOM   13160 N NH2   . ARG E 1 7   ? -60.020  23.765   -49.348 1.00 31.37  ? 7    ARG E NH2   1 
ATOM   13161 N N     . ILE E 1 8   ? -58.746  18.308   -52.776 1.00 32.89  ? 8    ILE E N     1 
ATOM   13162 C CA    . ILE E 1 8   ? -59.844  17.389   -52.557 1.00 35.68  ? 8    ILE E CA    1 
ATOM   13163 C C     . ILE E 1 8   ? -59.801  16.229   -53.568 1.00 42.12  ? 8    ILE E C     1 
ATOM   13164 O O     . ILE E 1 8   ? -60.042  15.076   -53.189 1.00 45.82  ? 8    ILE E O     1 
ATOM   13165 C CB    . ILE E 1 8   ? -61.183  18.141   -52.487 1.00 27.72  ? 8    ILE E CB    1 
ATOM   13166 C CG1   . ILE E 1 8   ? -61.227  19.048   -51.271 1.00 28.63  ? 8    ILE E CG1   1 
ATOM   13167 C CG2   . ILE E 1 8   ? -62.371  17.183   -52.498 1.00 29.36  ? 8    ILE E CG2   1 
ATOM   13168 C CD1   . ILE E 1 8   ? -62.487  19.905   -51.145 1.00 27.39  ? 8    ILE E CD1   1 
ATOM   13169 N N     . GLN E 1 9   ? -59.455  16.526   -54.828 1.00 44.67  ? 9    GLN E N     1 
ATOM   13170 C CA    . GLN E 1 9   ? -59.176  15.498   -55.826 1.00 49.63  ? 9    GLN E CA    1 
ATOM   13171 C C     . GLN E 1 9   ? -58.087  14.567   -55.295 1.00 43.14  ? 9    GLN E C     1 
ATOM   13172 O O     . GLN E 1 9   ? -58.195  13.349   -55.424 1.00 47.67  ? 9    GLN E O     1 
ATOM   13173 C CB    . GLN E 1 9   ? -58.655  16.053   -57.155 1.00 51.43  ? 9    GLN E CB    1 
ATOM   13174 C CG    . GLN E 1 9   ? -59.706  16.197   -58.251 1.00 83.06  ? 9    GLN E CG    1 
ATOM   13175 C CD    . GLN E 1 9   ? -59.330  17.206   -59.326 1.00 97.31  ? 9    GLN E CD    1 
ATOM   13176 O OE1   . GLN E 1 9   ? -60.025  18.207   -59.579 1.00 76.41  ? 9    GLN E OE1   1 
ATOM   13177 N NE2   . GLN E 1 9   ? -58.202  16.947   -59.973 1.00 96.87  ? 9    GLN E NE2   1 
ATOM   13178 N N     . HIS E 1 10  ? -57.028  15.150   -54.715 1.00 34.92  ? 10   HIS E N     1 
ATOM   13179 C CA    . HIS E 1 10  ? -55.929  14.347   -54.214 1.00 37.66  ? 10   HIS E CA    1 
ATOM   13180 C C     . HIS E 1 10  ? -56.428  13.473   -53.057 1.00 35.96  ? 10   HIS E C     1 
ATOM   13181 O O     . HIS E 1 10  ? -56.033  12.315   -52.939 1.00 34.65  ? 10   HIS E O     1 
ATOM   13182 C CB    . HIS E 1 10  ? -54.671  15.192   -53.957 1.00 39.23  ? 10   HIS E CB    1 
ATOM   13183 C CG    . HIS E 1 10  ? -53.488  14.391   -53.475 1.00 57.94  ? 10   HIS E CG    1 
ATOM   13184 N ND1   . HIS E 1 10  ? -53.062  14.353   -52.152 1.00 63.34  ? 10   HIS E ND1   1 
ATOM   13185 C CD2   . HIS E 1 10  ? -52.592  13.640   -54.152 1.00 61.97  ? 10   HIS E CD2   1 
ATOM   13186 C CE1   . HIS E 1 10  ? -51.984  13.581   -52.031 1.00 55.33  ? 10   HIS E CE1   1 
ATOM   13187 N NE2   . HIS E 1 10  ? -51.685  13.135   -53.228 1.00 58.54  ? 10   HIS E NE2   1 
ATOM   13188 N N     . TYR E 1 11  ? -57.324  14.028   -52.233 1.00 31.30  ? 11   TYR E N     1 
ATOM   13189 C CA    . TYR E 1 11  ? -57.889  13.336   -51.089 1.00 36.94  ? 11   TYR E CA    1 
ATOM   13190 C C     . TYR E 1 11  ? -58.651  12.086   -51.550 1.00 37.08  ? 11   TYR E C     1 
ATOM   13191 O O     . TYR E 1 11  ? -58.459  11.008   -51.000 1.00 35.61  ? 11   TYR E O     1 
ATOM   13192 C CB    . TYR E 1 11  ? -58.755  14.285   -50.249 1.00 30.80  ? 11   TYR E CB    1 
ATOM   13193 C CG    . TYR E 1 11  ? -59.535  13.532   -49.186 1.00 27.54  ? 11   TYR E CG    1 
ATOM   13194 C CD1   . TYR E 1 11  ? -58.946  13.189   -47.972 1.00 28.38  ? 11   TYR E CD1   1 
ATOM   13195 C CD2   . TYR E 1 11  ? -60.844  13.125   -49.420 1.00 25.97  ? 11   TYR E CD2   1 
ATOM   13196 C CE1   . TYR E 1 11  ? -59.650  12.485   -46.999 1.00 27.43  ? 11   TYR E CE1   1 
ATOM   13197 C CE2   . TYR E 1 11  ? -61.551  12.390   -48.482 1.00 25.27  ? 11   TYR E CE2   1 
ATOM   13198 C CZ    . TYR E 1 11  ? -60.951  12.079   -47.267 1.00 31.01  ? 11   TYR E CZ    1 
ATOM   13199 O OH    . TYR E 1 11  ? -61.661  11.357   -46.347 1.00 33.26  ? 11   TYR E OH    1 
ATOM   13200 N N     . GLU E 1 12  ? -59.502  12.233   -52.566 1.00 35.23  ? 12   GLU E N     1 
ATOM   13201 C CA    . GLU E 1 12  ? -60.304  11.123   -53.058 1.00 31.74  ? 12   GLU E CA    1 
ATOM   13202 C C     . GLU E 1 12  ? -59.423  10.017   -53.641 1.00 34.30  ? 12   GLU E C     1 
ATOM   13203 O O     . GLU E 1 12  ? -59.826  8.849    -53.656 1.00 35.35  ? 12   GLU E O     1 
ATOM   13204 C CB    . GLU E 1 12  ? -61.374  11.563   -54.061 1.00 28.79  ? 12   GLU E CB    1 
ATOM   13205 C CG    . GLU E 1 12  ? -62.338  12.584   -53.468 1.00 29.91  ? 12   GLU E CG    1 
ATOM   13206 C CD    . GLU E 1 12  ? -63.526  12.879   -54.363 1.00 38.06  ? 12   GLU E CD    1 
ATOM   13207 O OE1   . GLU E 1 12  ? -63.288  13.129   -55.569 1.00 43.42  ? 12   GLU E OE1   1 
ATOM   13208 O OE2   . GLU E 1 12  ? -64.688  12.899   -53.853 1.00 39.65  ? 12   GLU E OE2   1 
ATOM   13209 N N     . ASP E 1 13  ? -58.215  10.377   -54.097 1.00 32.98  ? 13   ASP E N     1 
ATOM   13210 C CA    . ASP E 1 13  ? -57.300  9.394    -54.646 1.00 31.95  ? 13   ASP E CA    1 
ATOM   13211 C C     . ASP E 1 13  ? -56.608  8.605    -53.539 1.00 33.53  ? 13   ASP E C     1 
ATOM   13212 O O     . ASP E 1 13  ? -55.935  7.609    -53.831 1.00 32.90  ? 13   ASP E O     1 
ATOM   13213 C CB    . ASP E 1 13  ? -56.224  10.035   -55.505 1.00 35.41  ? 13   ASP E CB    1 
ATOM   13214 C CG    . ASP E 1 13  ? -56.623  10.373   -56.940 1.00 43.00  ? 13   ASP E CG    1 
ATOM   13215 O OD1   . ASP E 1 13  ? -57.710  9.933    -57.389 1.00 44.65  ? 13   ASP E OD1   1 
ATOM   13216 O OD2   . ASP E 1 13  ? -55.839  11.062   -57.614 1.00 45.19  ? 13   ASP E OD2   1 
ATOM   13217 N N     . LEU E 1 14  ? -56.689  9.092    -52.293 1.00 31.54  ? 14   LEU E N     1 
ATOM   13218 C CA    . LEU E 1 14  ? -56.030  8.402    -51.197 1.00 32.24  ? 14   LEU E CA    1 
ATOM   13219 C C     . LEU E 1 14  ? -56.732  7.058    -50.961 1.00 34.04  ? 14   LEU E C     1 
ATOM   13220 O O     . LEU E 1 14  ? -56.075  6.048    -50.691 1.00 32.19  ? 14   LEU E O     1 
ATOM   13221 C CB    . LEU E 1 14  ? -56.048  9.271    -49.942 1.00 28.67  ? 14   LEU E CB    1 
ATOM   13222 C CG    . LEU E 1 14  ? -55.322  10.616   -50.041 1.00 30.18  ? 14   LEU E CG    1 
ATOM   13223 C CD1   . LEU E 1 14  ? -55.613  11.363   -48.736 1.00 31.13  ? 14   LEU E CD1   1 
ATOM   13224 C CD2   . LEU E 1 14  ? -53.822  10.463   -50.269 1.00 24.47  ? 14   LEU E CD2   1 
ATOM   13225 N N     . GLY E 1 15  ? -58.072  7.066    -51.031 1.00 30.58  ? 15   GLY E N     1 
ATOM   13226 C CA    . GLY E 1 15  ? -58.865  5.845    -50.962 1.00 29.56  ? 15   GLY E CA    1 
ATOM   13227 C C     . GLY E 1 15  ? -59.007  5.316    -49.537 1.00 28.91  ? 15   GLY E C     1 
ATOM   13228 O O     . GLY E 1 15  ? -60.108  5.291    -48.984 1.00 30.33  ? 15   GLY E O     1 
ATOM   13229 N N     . LEU E 1 16  ? -57.875  4.913    -48.949 1.00 27.39  ? 16   LEU E N     1 
ATOM   13230 C CA    . LEU E 1 16  ? -57.864  4.174    -47.700 1.00 29.00  ? 16   LEU E CA    1 
ATOM   13231 C C     . LEU E 1 16  ? -56.905  4.869    -46.741 1.00 29.70  ? 16   LEU E C     1 
ATOM   13232 O O     . LEU E 1 16  ? -55.754  5.175    -47.096 1.00 26.43  ? 16   LEU E O     1 
ATOM   13233 C CB    . LEU E 1 16  ? -57.435  2.728    -47.965 1.00 27.65  ? 16   LEU E CB    1 
ATOM   13234 C CG    . LEU E 1 16  ? -57.055  1.896    -46.736 1.00 24.33  ? 16   LEU E CG    1 
ATOM   13235 C CD1   . LEU E 1 16  ? -58.222  1.609    -45.821 1.00 24.54  ? 16   LEU E CD1   1 
ATOM   13236 C CD2   . LEU E 1 16  ? -56.390  0.568    -47.144 1.00 23.32  ? 16   LEU E CD2   1 
ATOM   13237 N N     . GLY E 1 17  ? -57.390  5.101    -45.515 1.00 29.18  ? 17   GLY E N     1 
ATOM   13238 C CA    . GLY E 1 17  ? -56.511  5.567    -44.457 1.00 24.89  ? 17   GLY E CA    1 
ATOM   13239 C C     . GLY E 1 17  ? -56.584  4.657    -43.236 1.00 26.45  ? 17   GLY E C     1 
ATOM   13240 O O     . GLY E 1 17  ? -57.558  3.930    -43.029 1.00 28.32  ? 17   GLY E O     1 
ATOM   13241 N N     . LEU E 1 18  ? -55.556  4.748    -42.404 1.00 27.85  ? 18   LEU E N     1 
ATOM   13242 C CA    . LEU E 1 18  ? -55.559  4.079    -41.123 1.00 31.17  ? 18   LEU E CA    1 
ATOM   13243 C C     . LEU E 1 18  ? -55.894  5.100    -40.033 1.00 34.14  ? 18   LEU E C     1 
ATOM   13244 O O     . LEU E 1 18  ? -55.275  6.179    -39.979 1.00 37.94  ? 18   LEU E O     1 
ATOM   13245 C CB    . LEU E 1 18  ? -54.117  3.580    -41.020 1.00 29.20  ? 18   LEU E CB    1 
ATOM   13246 C CG    . LEU E 1 18  ? -53.895  2.579    -39.890 1.00 36.59  ? 18   LEU E CG    1 
ATOM   13247 C CD1   . LEU E 1 18  ? -54.726  1.341    -40.233 1.00 36.49  ? 18   LEU E CD1   1 
ATOM   13248 C CD2   . LEU E 1 18  ? -52.432  2.254    -39.704 1.00 34.38  ? 18   LEU E CD2   1 
ATOM   13249 N N     . PHE E 1 19  ? -56.878  4.762    -39.188 1.00 27.36  ? 19   PHE E N     1 
ATOM   13250 C CA    . PHE E 1 19  ? -57.242  5.571    -38.038 1.00 23.28  ? 19   PHE E CA    1 
ATOM   13251 C C     . PHE E 1 19  ? -56.564  4.968    -36.816 1.00 26.38  ? 19   PHE E C     1 
ATOM   13252 O O     . PHE E 1 19  ? -56.622  3.749    -36.635 1.00 28.84  ? 19   PHE E O     1 
ATOM   13253 C CB    . PHE E 1 19  ? -58.753  5.467    -37.860 1.00 23.09  ? 19   PHE E CB    1 
ATOM   13254 C CG    . PHE E 1 19  ? -59.491  6.675    -37.295 1.00 25.99  ? 19   PHE E CG    1 
ATOM   13255 C CD1   . PHE E 1 19  ? -58.834  7.610    -36.497 1.00 27.10  ? 19   PHE E CD1   1 
ATOM   13256 C CD2   . PHE E 1 19  ? -60.862  6.848    -37.526 1.00 24.71  ? 19   PHE E CD2   1 
ATOM   13257 C CE1   . PHE E 1 19  ? -59.510  8.715    -35.970 1.00 26.72  ? 19   PHE E CE1   1 
ATOM   13258 C CE2   . PHE E 1 19  ? -61.539  7.959    -37.021 1.00 31.09  ? 19   PHE E CE2   1 
ATOM   13259 C CZ    . PHE E 1 19  ? -60.854  8.894    -36.249 1.00 31.50  ? 19   PHE E CZ    1 
ATOM   13260 N N     . ILE E 1 20  ? -55.930  5.806    -35.979 1.00 25.16  ? 20   ILE E N     1 
ATOM   13261 C CA    . ILE E 1 20  ? -55.243  5.307    -34.792 1.00 24.21  ? 20   ILE E CA    1 
ATOM   13262 C C     . ILE E 1 20  ? -55.719  6.050    -33.541 1.00 26.98  ? 20   ILE E C     1 
ATOM   13263 O O     . ILE E 1 20  ? -55.563  7.270    -33.443 1.00 26.86  ? 20   ILE E O     1 
ATOM   13264 C CB    . ILE E 1 20  ? -53.724  5.427    -34.960 1.00 25.83  ? 20   ILE E CB    1 
ATOM   13265 C CG1   . ILE E 1 20  ? -53.264  4.610    -36.167 1.00 28.06  ? 20   ILE E CG1   1 
ATOM   13266 C CG2   . ILE E 1 20  ? -53.012  5.014    -33.665 1.00 24.25  ? 20   ILE E CG2   1 
ATOM   13267 C CD1   . ILE E 1 20  ? -51.764  4.688    -36.380 1.00 31.72  ? 20   ILE E CD1   1 
ATOM   13268 N N     . HIS E 1 21  ? -56.291  5.296    -32.592 1.00 25.02  ? 21   HIS E N     1 
ATOM   13269 C CA    . HIS E 1 21  ? -56.718  5.810    -31.305 1.00 25.30  ? 21   HIS E CA    1 
ATOM   13270 C C     . HIS E 1 21  ? -55.707  5.392    -30.246 1.00 29.41  ? 21   HIS E C     1 
ATOM   13271 O O     . HIS E 1 21  ? -55.481  4.197    -30.007 1.00 30.20  ? 21   HIS E O     1 
ATOM   13272 C CB    . HIS E 1 21  ? -58.100  5.275    -30.917 1.00 26.75  ? 21   HIS E CB    1 
ATOM   13273 C CG    . HIS E 1 21  ? -59.204  6.026    -31.580 1.00 28.33  ? 21   HIS E CG    1 
ATOM   13274 N ND1   . HIS E 1 21  ? -59.477  5.926    -32.927 1.00 25.85  ? 21   HIS E ND1   1 
ATOM   13275 C CD2   . HIS E 1 21  ? -60.061  6.939    -31.111 1.00 30.28  ? 21   HIS E CD2   1 
ATOM   13276 C CE1   . HIS E 1 21  ? -60.477  6.748    -33.231 1.00 27.05  ? 21   HIS E CE1   1 
ATOM   13277 N NE2   . HIS E 1 21  ? -60.852  7.368    -32.148 1.00 26.27  ? 21   HIS E NE2   1 
ATOM   13278 N N     . TRP E 1 22  ? -55.088  6.395    -29.633 1.00 26.76  ? 22   TRP E N     1 
ATOM   13279 C CA    . TRP E 1 22  ? -54.130  6.155    -28.568 1.00 25.29  ? 22   TRP E CA    1 
ATOM   13280 C C     . TRP E 1 22  ? -54.147  7.368    -27.638 1.00 28.21  ? 22   TRP E C     1 
ATOM   13281 O O     . TRP E 1 22  ? -54.006  8.500    -28.101 1.00 24.11  ? 22   TRP E O     1 
ATOM   13282 C CB    . TRP E 1 22  ? -52.748  6.010    -29.191 1.00 21.89  ? 22   TRP E CB    1 
ATOM   13283 C CG    . TRP E 1 22  ? -51.664  5.702    -28.204 1.00 24.54  ? 22   TRP E CG    1 
ATOM   13284 C CD1   . TRP E 1 22  ? -51.743  4.921    -27.089 1.00 25.47  ? 22   TRP E CD1   1 
ATOM   13285 C CD2   . TRP E 1 22  ? -50.301  6.176    -28.273 1.00 22.71  ? 22   TRP E CD2   1 
ATOM   13286 N NE1   . TRP E 1 22  ? -50.518  4.863    -26.462 1.00 23.14  ? 22   TRP E NE1   1 
ATOM   13287 C CE2   . TRP E 1 22  ? -49.621  5.631    -27.166 1.00 22.13  ? 22   TRP E CE2   1 
ATOM   13288 C CE3   . TRP E 1 22  ? -49.599  6.994    -29.171 1.00 22.08  ? 22   TRP E CE3   1 
ATOM   13289 C CZ2   . TRP E 1 22  ? -48.269  5.892    -26.931 1.00 22.43  ? 22   TRP E CZ2   1 
ATOM   13290 C CZ3   . TRP E 1 22  ? -48.263  7.243    -28.942 1.00 20.13  ? 22   TRP E CZ3   1 
ATOM   13291 C CH2   . TRP E 1 22  ? -47.620  6.704    -27.833 1.00 20.75  ? 22   TRP E CH2   1 
ATOM   13292 N N     . GLY E 1 23  ? -54.341  7.111    -26.345 1.00 27.85  ? 23   GLY E N     1 
ATOM   13293 C CA    . GLY E 1 23  ? -54.350  8.155    -25.336 1.00 30.06  ? 23   GLY E CA    1 
ATOM   13294 C C     . GLY E 1 23  ? -54.137  7.532    -23.959 1.00 30.13  ? 23   GLY E C     1 
ATOM   13295 O O     . GLY E 1 23  ? -53.735  6.378    -23.871 1.00 26.68  ? 23   GLY E O     1 
ATOM   13296 N N     . LEU E 1 24  ? -54.448  8.281    -22.895 1.00 28.32  ? 24   LEU E N     1 
ATOM   13297 C CA    . LEU E 1 24  ? -54.266  7.734    -21.558 1.00 26.50  ? 24   LEU E CA    1 
ATOM   13298 C C     . LEU E 1 24  ? -55.210  6.545    -21.384 1.00 25.15  ? 24   LEU E C     1 
ATOM   13299 O O     . LEU E 1 24  ? -54.851  5.581    -20.711 1.00 27.80  ? 24   LEU E O     1 
ATOM   13300 C CB    . LEU E 1 24  ? -54.468  8.791    -20.468 1.00 25.37  ? 24   LEU E CB    1 
ATOM   13301 C CG    . LEU E 1 24  ? -53.530  10.008   -20.554 1.00 28.47  ? 24   LEU E CG    1 
ATOM   13302 C CD1   . LEU E 1 24  ? -53.863  11.030   -19.470 1.00 26.07  ? 24   LEU E CD1   1 
ATOM   13303 C CD2   . LEU E 1 24  ? -52.045  9.661    -20.570 1.00 25.26  ? 24   LEU E CD2   1 
ATOM   13304 N N     . TYR E 1 25  ? -56.402  6.618    -22.000 1.00 23.83  ? 25   TYR E N     1 
ATOM   13305 C CA    . TYR E 1 25  ? -57.414  5.577    -21.902 1.00 25.02  ? 25   TYR E CA    1 
ATOM   13306 C C     . TYR E 1 25  ? -56.833  4.217    -22.286 1.00 25.95  ? 25   TYR E C     1 
ATOM   13307 O O     . TYR E 1 25  ? -57.264  3.194    -21.747 1.00 29.26  ? 25   TYR E O     1 
ATOM   13308 C CB    . TYR E 1 25  ? -58.640  5.824    -22.786 1.00 23.33  ? 25   TYR E CB    1 
ATOM   13309 C CG    . TYR E 1 25  ? -58.292  6.338    -24.175 1.00 26.22  ? 25   TYR E CG    1 
ATOM   13310 C CD1   . TYR E 1 25  ? -57.950  5.466    -25.218 1.00 24.65  ? 25   TYR E CD1   1 
ATOM   13311 C CD2   . TYR E 1 25  ? -58.321  7.705    -24.455 1.00 24.68  ? 25   TYR E CD2   1 
ATOM   13312 C CE1   . TYR E 1 25  ? -57.641  5.950    -26.482 1.00 25.99  ? 25   TYR E CE1   1 
ATOM   13313 C CE2   . TYR E 1 25  ? -58.007  8.197    -25.716 1.00 27.95  ? 25   TYR E CE2   1 
ATOM   13314 C CZ    . TYR E 1 25  ? -57.668  7.315    -26.736 1.00 29.91  ? 25   TYR E CZ    1 
ATOM   13315 O OH    . TYR E 1 25  ? -57.327  7.816    -27.970 1.00 30.05  ? 25   TYR E OH    1 
ATOM   13316 N N     . SER E 1 26  ? -55.850  4.209    -23.189 1.00 24.72  ? 26   SER E N     1 
ATOM   13317 C CA    . SER E 1 26  ? -55.298  2.961    -23.708 1.00 25.37  ? 26   SER E CA    1 
ATOM   13318 C C     . SER E 1 26  ? -54.726  2.109    -22.583 1.00 28.39  ? 26   SER E C     1 
ATOM   13319 O O     . SER E 1 26  ? -54.717  0.879    -22.672 1.00 28.94  ? 26   SER E O     1 
ATOM   13320 C CB    . SER E 1 26  ? -54.249  3.231    -24.775 1.00 25.16  ? 26   SER E CB    1 
ATOM   13321 O OG    . SER E 1 26  ? -54.784  4.056    -25.798 1.00 27.80  ? 26   SER E OG    1 
ATOM   13322 N N     . GLN E 1 27  ? -54.246  2.761    -21.515 1.00 29.51  ? 27   GLN E N     1 
ATOM   13323 C CA    . GLN E 1 27  ? -53.654  1.991    -20.425 1.00 30.29  ? 27   GLN E CA    1 
ATOM   13324 C C     . GLN E 1 27  ? -54.691  1.124    -19.722 1.00 27.28  ? 27   GLN E C     1 
ATOM   13325 O O     . GLN E 1 27  ? -54.318  0.133    -19.138 1.00 28.25  ? 27   GLN E O     1 
ATOM   13326 C CB    . GLN E 1 27  ? -52.920  2.836    -19.392 1.00 28.81  ? 27   GLN E CB    1 
ATOM   13327 C CG    . GLN E 1 27  ? -51.583  3.356    -19.913 1.00 29.49  ? 27   GLN E CG    1 
ATOM   13328 C CD    . GLN E 1 27  ? -51.046  4.450    -19.014 1.00 33.35  ? 27   GLN E CD    1 
ATOM   13329 O OE1   . GLN E 1 27  ? -51.040  5.638    -19.380 1.00 28.38  ? 27   GLN E OE1   1 
ATOM   13330 N NE2   . GLN E 1 27  ? -50.643  4.052    -17.810 1.00 28.84  ? 27   GLN E NE2   1 
ATOM   13331 N N     . MET E 1 28  ? -55.979  1.463    -19.781 1.00 27.71  ? 28   MET E N     1 
ATOM   13332 C CA    . MET E 1 28  ? -56.968  0.683    -19.050 1.00 29.92  ? 28   MET E CA    1 
ATOM   13333 C C     . MET E 1 28  ? -57.638  -0.367   -19.949 1.00 30.03  ? 28   MET E C     1 
ATOM   13334 O O     . MET E 1 28  ? -58.271  -1.279   -19.436 1.00 27.93  ? 28   MET E O     1 
ATOM   13335 C CB    . MET E 1 28  ? -58.113  1.592    -18.631 1.00 33.16  ? 28   MET E CB    1 
ATOM   13336 C CG    . MET E 1 28  ? -57.641  2.917    -18.107 1.00 48.13  ? 28   MET E CG    1 
ATOM   13337 S SD    . MET E 1 28  ? -57.735  2.849    -16.314 1.00 69.15  ? 28   MET E SD    1 
ATOM   13338 C CE    . MET E 1 28  ? -56.441  1.686    -15.860 1.00 39.89  ? 28   MET E CE    1 
ATOM   13339 N N     . ALA E 1 29  ? -57.612  -0.168   -21.278 1.00 27.95  ? 29   ALA E N     1 
ATOM   13340 C CA    . ALA E 1 29  ? -58.082  -1.156   -22.244 1.00 27.28  ? 29   ALA E CA    1 
ATOM   13341 C C     . ALA E 1 29  ? -59.564  -1.462   -22.027 1.00 29.13  ? 29   ALA E C     1 
ATOM   13342 O O     . ALA E 1 29  ? -60.001  -2.618   -22.154 1.00 31.47  ? 29   ALA E O     1 
ATOM   13343 C CB    . ALA E 1 29  ? -57.212  -2.416   -22.180 1.00 22.44  ? 29   ALA E CB    1 
ATOM   13344 N N     . VAL E 1 30  ? -60.338  -0.417   -21.702 1.00 25.69  ? 30   VAL E N     1 
ATOM   13345 C CA    . VAL E 1 30  ? -61.784  -0.580   -21.569 1.00 25.64  ? 30   VAL E CA    1 
ATOM   13346 C C     . VAL E 1 30  ? -62.480  0.520    -22.370 1.00 26.11  ? 30   VAL E C     1 
ATOM   13347 O O     . VAL E 1 30  ? -63.510  1.014    -21.940 1.00 27.59  ? 30   VAL E O     1 
ATOM   13348 C CB    . VAL E 1 30  ? -62.301  -0.675   -20.108 1.00 23.74  ? 30   VAL E CB    1 
ATOM   13349 C CG1   . VAL E 1 30  ? -61.924  -2.003   -19.436 1.00 22.15  ? 30   VAL E CG1   1 
ATOM   13350 C CG2   . VAL E 1 30  ? -61.824  0.504    -19.255 1.00 21.22  ? 30   VAL E CG2   1 
ATOM   13351 N N     . GLY E 1 31  ? -61.918  0.912    -23.527 1.00 25.25  ? 31   GLY E N     1 
ATOM   13352 C CA    . GLY E 1 31  ? -62.594  1.884    -24.383 1.00 27.64  ? 31   GLY E CA    1 
ATOM   13353 C C     . GLY E 1 31  ? -62.119  3.320    -24.132 1.00 27.56  ? 31   GLY E C     1 
ATOM   13354 O O     . GLY E 1 31  ? -61.720  3.663    -23.020 1.00 28.04  ? 31   GLY E O     1 
ATOM   13355 N N     . GLU E 1 32  ? -62.179  4.162    -25.175 1.00 24.80  ? 32   GLU E N     1 
ATOM   13356 C CA    . GLU E 1 32  ? -61.649  5.511    -25.100 1.00 24.13  ? 32   GLU E CA    1 
ATOM   13357 C C     . GLU E 1 32  ? -62.560  6.441    -24.283 1.00 26.56  ? 32   GLU E C     1 
ATOM   13358 O O     . GLU E 1 32  ? -62.100  7.482    -23.829 1.00 27.82  ? 32   GLU E O     1 
ATOM   13359 C CB    . GLU E 1 32  ? -61.307  6.073    -26.479 1.00 22.50  ? 32   GLU E CB    1 
ATOM   13360 C CG    . GLU E 1 32  ? -62.523  6.350    -27.357 1.00 23.37  ? 32   GLU E CG    1 
ATOM   13361 C CD    . GLU E 1 32  ? -63.320  5.172    -27.926 1.00 27.40  ? 32   GLU E CD    1 
ATOM   13362 O OE1   . GLU E 1 32  ? -63.007  3.960    -27.756 1.00 26.16  ? 32   GLU E OE1   1 
ATOM   13363 O OE2   . GLU E 1 32  ? -64.319  5.505    -28.599 1.00 28.66  ? 32   GLU E OE2   1 
ATOM   13364 N N     . TRP E 1 33  ? -63.850  6.105    -24.125 1.00 26.27  ? 33   TRP E N     1 
ATOM   13365 C CA    . TRP E 1 33  ? -64.761  6.936    -23.340 1.00 25.10  ? 33   TRP E CA    1 
ATOM   13366 C C     . TRP E 1 33  ? -64.757  6.560    -21.856 1.00 26.85  ? 33   TRP E C     1 
ATOM   13367 O O     . TRP E 1 33  ? -65.642  7.003    -21.125 1.00 32.70  ? 33   TRP E O     1 
ATOM   13368 C CB    . TRP E 1 33  ? -66.201  6.846    -23.877 1.00 23.97  ? 33   TRP E CB    1 
ATOM   13369 C CG    . TRP E 1 33  ? -66.491  7.691    -25.093 1.00 25.08  ? 33   TRP E CG    1 
ATOM   13370 C CD1   . TRP E 1 33  ? -65.947  7.571    -26.343 1.00 25.70  ? 33   TRP E CD1   1 
ATOM   13371 C CD2   . TRP E 1 33  ? -67.432  8.782    -25.179 1.00 24.80  ? 33   TRP E CD2   1 
ATOM   13372 N NE1   . TRP E 1 33  ? -66.434  8.539    -27.185 1.00 27.36  ? 33   TRP E NE1   1 
ATOM   13373 C CE2   . TRP E 1 33  ? -67.360  9.292    -26.506 1.00 28.69  ? 33   TRP E CE2   1 
ATOM   13374 C CE3   . TRP E 1 33  ? -68.314  9.397    -24.276 1.00 26.50  ? 33   TRP E CE3   1 
ATOM   13375 C CZ2   . TRP E 1 33  ? -68.149  10.371   -26.941 1.00 27.71  ? 33   TRP E CZ2   1 
ATOM   13376 C CZ3   . TRP E 1 33  ? -69.094  10.456   -24.715 1.00 30.77  ? 33   TRP E CZ3   1 
ATOM   13377 C CH2   . TRP E 1 33  ? -68.994  10.954   -26.022 1.00 25.17  ? 33   TRP E CH2   1 
ATOM   13378 N N     . THR E 1 34  ? -63.790  5.761    -21.393 1.00 26.90  ? 34   THR E N     1 
ATOM   13379 C CA    . THR E 1 34  ? -63.874  5.183    -20.055 1.00 29.45  ? 34   THR E CA    1 
ATOM   13380 C C     . THR E 1 34  ? -64.046  6.265    -18.962 1.00 36.89  ? 34   THR E C     1 
ATOM   13381 O O     . THR E 1 34  ? -64.820  6.074    -18.010 1.00 31.79  ? 34   THR E O     1 
ATOM   13382 C CB    . THR E 1 34  ? -62.681  4.259    -19.799 1.00 27.29  ? 34   THR E CB    1 
ATOM   13383 O OG1   . THR E 1 34  ? -62.898  3.757    -18.481 1.00 28.54  ? 34   THR E OG1   1 
ATOM   13384 C CG2   . THR E 1 34  ? -61.339  4.974    -19.792 1.00 26.17  ? 34   THR E CG2   1 
ATOM   13385 N N     . GLU E 1 35  ? -63.337  7.407    -19.083 1.00 32.78  ? 35   GLU E N     1 
ATOM   13386 C CA    . GLU E 1 35  ? -63.386  8.415    -18.032 1.00 34.58  ? 35   GLU E CA    1 
ATOM   13387 C C     . GLU E 1 35  ? -64.820  8.885    -17.768 1.00 30.96  ? 35   GLU E C     1 
ATOM   13388 O O     . GLU E 1 35  ? -65.240  8.941    -16.613 1.00 28.21  ? 35   GLU E O     1 
ATOM   13389 C CB    . GLU E 1 35  ? -62.448  9.596    -18.260 1.00 37.75  ? 35   GLU E CB    1 
ATOM   13390 C CG    . GLU E 1 35  ? -62.486  10.592   -17.104 1.00 40.58  ? 35   GLU E CG    1 
ATOM   13391 C CD    . GLU E 1 35  ? -61.606  11.815   -17.321 1.00 41.56  ? 35   GLU E CD    1 
ATOM   13392 O OE1   . GLU E 1 35  ? -61.285  12.139   -18.496 1.00 35.31  ? 35   GLU E OE1   1 
ATOM   13393 O OE2   . GLU E 1 35  ? -61.199  12.415   -16.296 1.00 39.86  ? 35   GLU E OE2   1 
ATOM   13394 N N     . LEU E 1 36  ? -65.564  9.204    -18.829 1.00 31.00  ? 36   LEU E N     1 
ATOM   13395 C CA    . LEU E 1 36  ? -66.942  9.654    -18.674 1.00 30.50  ? 36   LEU E CA    1 
ATOM   13396 C C     . LEU E 1 36  ? -67.862  8.468    -18.362 1.00 34.10  ? 36   LEU E C     1 
ATOM   13397 O O     . LEU E 1 36  ? -68.598  8.505    -17.386 1.00 37.53  ? 36   LEU E O     1 
ATOM   13398 C CB    . LEU E 1 36  ? -67.426  10.427   -19.902 1.00 28.88  ? 36   LEU E CB    1 
ATOM   13399 C CG    . LEU E 1 36  ? -68.844  11.000   -19.803 1.00 34.02  ? 36   LEU E CG    1 
ATOM   13400 C CD1   . LEU E 1 36  ? -68.907  12.055   -18.682 1.00 39.90  ? 36   LEU E CD1   1 
ATOM   13401 C CD2   . LEU E 1 36  ? -69.210  11.675   -21.089 1.00 31.97  ? 36   LEU E CD2   1 
ATOM   13402 N N     . ILE E 1 37  ? -67.816  7.406    -19.175 1.00 34.68  ? 37   ILE E N     1 
ATOM   13403 C CA    . ILE E 1 37  ? -68.857  6.388    -19.105 1.00 34.31  ? 37   ILE E CA    1 
ATOM   13404 C C     . ILE E 1 37  ? -68.749  5.557    -17.824 1.00 32.27  ? 37   ILE E C     1 
ATOM   13405 O O     . ILE E 1 37  ? -69.774  5.133    -17.292 1.00 30.57  ? 37   ILE E O     1 
ATOM   13406 C CB    . ILE E 1 37  ? -68.926  5.539    -20.390 1.00 30.55  ? 37   ILE E CB    1 
ATOM   13407 C CG1   . ILE E 1 37  ? -69.426  6.411    -21.533 1.00 31.22  ? 37   ILE E CG1   1 
ATOM   13408 C CG2   . ILE E 1 37  ? -69.815  4.309    -20.197 1.00 27.01  ? 37   ILE E CG2   1 
ATOM   13409 C CD1   . ILE E 1 37  ? -69.396  5.734    -22.893 1.00 34.27  ? 37   ILE E CD1   1 
ATOM   13410 N N     . HIS E 1 38  ? -67.531  5.328    -17.331 1.00 27.06  ? 38   HIS E N     1 
ATOM   13411 C CA    . HIS E 1 38  ? -67.382  4.580    -16.096 1.00 31.86  ? 38   HIS E CA    1 
ATOM   13412 C C     . HIS E 1 38  ? -67.359  5.519    -14.884 1.00 35.56  ? 38   HIS E C     1 
ATOM   13413 O O     . HIS E 1 38  ? -66.972  5.067    -13.807 1.00 29.67  ? 38   HIS E O     1 
ATOM   13414 C CB    . HIS E 1 38  ? -66.092  3.741    -16.112 1.00 32.79  ? 38   HIS E CB    1 
ATOM   13415 C CG    . HIS E 1 38  ? -66.154  2.608    -17.084 1.00 39.12  ? 38   HIS E CG    1 
ATOM   13416 N ND1   . HIS E 1 38  ? -65.161  2.382    -18.022 1.00 37.35  ? 38   HIS E ND1   1 
ATOM   13417 C CD2   . HIS E 1 38  ? -67.130  1.676    -17.322 1.00 38.32  ? 38   HIS E CD2   1 
ATOM   13418 C CE1   . HIS E 1 38  ? -65.506  1.337    -18.771 1.00 35.67  ? 38   HIS E CE1   1 
ATOM   13419 N NE2   . HIS E 1 38  ? -66.720  0.921    -18.391 1.00 37.27  ? 38   HIS E NE2   1 
ATOM   13420 N N     . HIS E 1 39  ? -67.690  6.819    -15.076 1.00 36.01  ? 39   HIS E N     1 
ATOM   13421 C CA    . HIS E 1 39  ? -67.838  7.789    -13.993 1.00 44.94  ? 39   HIS E CA    1 
ATOM   13422 C C     . HIS E 1 39  ? -66.575  7.796    -13.119 1.00 42.38  ? 39   HIS E C     1 
ATOM   13423 O O     . HIS E 1 39  ? -66.634  7.622    -11.904 1.00 36.91  ? 39   HIS E O     1 
ATOM   13424 C CB    . HIS E 1 39  ? -69.165  7.595    -13.220 1.00 54.33  ? 39   HIS E CB    1 
ATOM   13425 C CG    . HIS E 1 39  ? -69.492  8.704    -12.235 1.00 101.75 ? 39   HIS E CG    1 
ATOM   13426 N ND1   . HIS E 1 39  ? -69.846  9.994    -12.601 1.00 111.36 ? 39   HIS E ND1   1 
ATOM   13427 C CD2   . HIS E 1 39  ? -69.480  8.716    -10.870 1.00 109.39 ? 39   HIS E CD2   1 
ATOM   13428 C CE1   . HIS E 1 39  ? -70.034  10.743   -11.514 1.00 96.80  ? 39   HIS E CE1   1 
ATOM   13429 N NE2   . HIS E 1 39  ? -69.821  9.987    -10.451 1.00 99.77  ? 39   HIS E NE2   1 
ATOM   13430 N N     . ARG E 1 40  ? -65.404  7.937    -13.729 1.00 42.29  ? 40   ARG E N     1 
ATOM   13431 C CA    . ARG E 1 40  ? -64.189  7.829    -12.933 1.00 42.20  ? 40   ARG E CA    1 
ATOM   13432 C C     . ARG E 1 40  ? -63.906  9.159    -12.239 1.00 40.55  ? 40   ARG E C     1 
ATOM   13433 O O     . ARG E 1 40  ? -64.302  10.214   -12.728 1.00 37.70  ? 40   ARG E O     1 
ATOM   13434 C CB    . ARG E 1 40  ? -63.013  7.482    -13.855 1.00 39.16  ? 40   ARG E CB    1 
ATOM   13435 C CG    . ARG E 1 40  ? -63.109  6.038    -14.318 1.00 42.84  ? 40   ARG E CG    1 
ATOM   13436 C CD    . ARG E 1 40  ? -61.868  5.749    -15.146 1.00 48.43  ? 40   ARG E CD    1 
ATOM   13437 N NE    . ARG E 1 40  ? -61.926  4.480    -15.876 1.00 54.05  ? 40   ARG E NE    1 
ATOM   13438 C CZ    . ARG E 1 40  ? -61.667  3.272    -15.388 1.00 52.69  ? 40   ARG E CZ    1 
ATOM   13439 N NH1   . ARG E 1 40  ? -61.396  3.123    -14.111 1.00 49.85  ? 40   ARG E NH1   1 
ATOM   13440 N NH2   . ARG E 1 40  ? -61.710  2.214    -16.173 1.00 41.54  ? 40   ARG E NH2   1 
ATOM   13441 N N     . ASN E 1 41  ? -63.213  9.098    -11.102 1.00 40.06  ? 41   ASN E N     1 
ATOM   13442 C CA    . ASN E 1 41  ? -62.657  10.283   -10.471 1.00 39.46  ? 41   ASN E CA    1 
ATOM   13443 C C     . ASN E 1 41  ? -61.635  10.946   -11.417 1.00 36.84  ? 41   ASN E C     1 
ATOM   13444 O O     . ASN E 1 41  ? -60.597  10.365   -11.766 1.00 31.10  ? 41   ASN E O     1 
ATOM   13445 C CB    . ASN E 1 41  ? -62.033  9.899    -9.124  1.00 41.24  ? 41   ASN E CB    1 
ATOM   13446 C CG    . ASN E 1 41  ? -61.372  11.094   -8.466  1.00 45.51  ? 41   ASN E CG    1 
ATOM   13447 O OD1   . ASN E 1 41  ? -60.195  11.371   -8.707  1.00 44.69  ? 41   ASN E OD1   1 
ATOM   13448 N ND2   . ASN E 1 41  ? -62.116  11.905   -7.737  1.00 44.24  ? 41   ASN E ND2   1 
ATOM   13449 N N     . GLN E 1 42  ? -61.881  12.206   -11.776 1.00 34.12  ? 42   GLN E N     1 
ATOM   13450 C CA    . GLN E 1 42  ? -61.013  12.884   -12.731 1.00 36.02  ? 42   GLN E CA    1 
ATOM   13451 C C     . GLN E 1 42  ? -59.550  12.899   -12.272 1.00 42.99  ? 42   GLN E C     1 
ATOM   13452 O O     . GLN E 1 42  ? -58.640  12.615   -13.062 1.00 44.96  ? 42   GLN E O     1 
ATOM   13453 C CB    . GLN E 1 42  ? -61.533  14.273   -13.077 1.00 30.70  ? 42   GLN E CB    1 
ATOM   13454 C CG    . GLN E 1 42  ? -60.612  14.986   -14.053 1.00 39.02  ? 42   GLN E CG    1 
ATOM   13455 C CD    . GLN E 1 42  ? -61.234  16.243   -14.612 1.00 42.56  ? 42   GLN E CD    1 
ATOM   13456 O OE1   . GLN E 1 42  ? -62.294  16.664   -14.157 1.00 53.30  ? 42   GLN E OE1   1 
ATOM   13457 N NE2   . GLN E 1 42  ? -60.593  16.868   -15.585 1.00 43.45  ? 42   GLN E NE2   1 
ATOM   13458 N N     . HIS E 1 43  ? -59.322  13.239   -10.997 1.00 43.33  ? 43   HIS E N     1 
ATOM   13459 C CA    . HIS E 1 43  ? -57.961  13.360   -10.486 1.00 41.64  ? 43   HIS E CA    1 
ATOM   13460 C C     . HIS E 1 43  ? -57.237  12.022   -10.647 1.00 35.49  ? 43   HIS E C     1 
ATOM   13461 O O     . HIS E 1 43  ? -56.066  11.992   -11.028 1.00 35.44  ? 43   HIS E O     1 
ATOM   13462 C CB    . HIS E 1 43  ? -57.945  13.942   -9.060  1.00 42.48  ? 43   HIS E CB    1 
ATOM   13463 C CG    . HIS E 1 43  ? -56.603  13.814   -8.404  1.00 50.20  ? 43   HIS E CG    1 
ATOM   13464 N ND1   . HIS E 1 43  ? -55.627  14.794   -8.474  1.00 49.00  ? 43   HIS E ND1   1 
ATOM   13465 C CD2   . HIS E 1 43  ? -56.046  12.763   -7.719  1.00 50.90  ? 43   HIS E CD2   1 
ATOM   13466 C CE1   . HIS E 1 43  ? -54.546  14.373   -7.810  1.00 59.88  ? 43   HIS E CE1   1 
ATOM   13467 N NE2   . HIS E 1 43  ? -54.759  13.123   -7.373  1.00 53.25  ? 43   HIS E NE2   1 
ATOM   13468 N N     . ASP E 1 44  ? -57.925  10.923   -10.316 1.00 32.66  ? 44   ASP E N     1 
ATOM   13469 C CA    . ASP E 1 44  ? -57.316  9.599    -10.328 1.00 39.41  ? 44   ASP E CA    1 
ATOM   13470 C C     . ASP E 1 44  ? -57.019  9.166    -11.758 1.00 38.85  ? 44   ASP E C     1 
ATOM   13471 O O     . ASP E 1 44  ? -55.928  8.693    -12.032 1.00 33.33  ? 44   ASP E O     1 
ATOM   13472 C CB    . ASP E 1 44  ? -58.134  8.582    -9.546  1.00 42.39  ? 44   ASP E CB    1 
ATOM   13473 C CG    . ASP E 1 44  ? -58.248  8.871    -8.049  1.00 51.65  ? 44   ASP E CG    1 
ATOM   13474 O OD1   . ASP E 1 44  ? -57.450  9.690    -7.528  1.00 61.25  ? 44   ASP E OD1   1 
ATOM   13475 O OD2   . ASP E 1 44  ? -59.174  8.338    -7.416  1.00 52.46  ? 44   ASP E OD2   1 
ATOM   13476 N N     . TYR E 1 45  ? -57.975  9.382    -12.668 1.00 38.88  ? 45   TYR E N     1 
ATOM   13477 C CA    . TYR E 1 45  ? -57.797  9.047    -14.067 1.00 37.55  ? 45   TYR E CA    1 
ATOM   13478 C C     . TYR E 1 45  ? -56.612  9.814    -14.656 1.00 38.64  ? 45   TYR E C     1 
ATOM   13479 O O     . TYR E 1 45  ? -55.766  9.210    -15.321 1.00 35.42  ? 45   TYR E O     1 
ATOM   13480 C CB    . TYR E 1 45  ? -59.111  9.282    -14.809 1.00 37.89  ? 45   TYR E CB    1 
ATOM   13481 C CG    . TYR E 1 45  ? -58.997  9.003    -16.302 1.00 35.99  ? 45   TYR E CG    1 
ATOM   13482 C CD1   . TYR E 1 45  ? -59.146  7.707    -16.807 1.00 31.86  ? 45   TYR E CD1   1 
ATOM   13483 C CD2   . TYR E 1 45  ? -58.719  10.030   -17.200 1.00 29.06  ? 45   TYR E CD2   1 
ATOM   13484 C CE1   . TYR E 1 45  ? -59.056  7.441    -18.170 1.00 26.34  ? 45   TYR E CE1   1 
ATOM   13485 C CE2   . TYR E 1 45  ? -58.633  9.784    -18.558 1.00 28.37  ? 45   TYR E CE2   1 
ATOM   13486 C CZ    . TYR E 1 45  ? -58.797  8.487    -19.041 1.00 28.88  ? 45   TYR E CZ    1 
ATOM   13487 O OH    . TYR E 1 45  ? -58.713  8.281    -20.382 1.00 27.52  ? 45   TYR E OH    1 
ATOM   13488 N N     . GLU E 1 46  ? -56.509  11.119   -14.363 1.00 37.29  ? 46   GLU E N     1 
ATOM   13489 C CA    . GLU E 1 46  ? -55.464  11.955   -14.946 1.00 35.33  ? 46   GLU E CA    1 
ATOM   13490 C C     . GLU E 1 46  ? -54.064  11.582   -14.454 1.00 33.80  ? 46   GLU E C     1 
ATOM   13491 O O     . GLU E 1 46  ? -53.073  11.946   -15.096 1.00 37.50  ? 46   GLU E O     1 
ATOM   13492 C CB    . GLU E 1 46  ? -55.812  13.433   -14.861 1.00 34.40  ? 46   GLU E CB    1 
ATOM   13493 C CG    . GLU E 1 46  ? -57.078  13.761   -15.638 1.00 38.56  ? 46   GLU E CG    1 
ATOM   13494 C CD    . GLU E 1 46  ? -57.354  15.254   -15.773 1.00 44.04  ? 46   GLU E CD    1 
ATOM   13495 O OE1   . GLU E 1 46  ? -56.572  15.999   -15.143 1.00 50.04  ? 46   GLU E OE1   1 
ATOM   13496 O OE2   . GLU E 1 46  ? -58.236  15.689   -16.557 1.00 39.57  ? 46   GLU E OE2   1 
ATOM   13497 N N     . GLN E 1 47  ? -53.976  10.809   -13.361 1.00 30.84  ? 47   GLN E N     1 
ATOM   13498 C CA    . GLN E 1 47  ? -52.692  10.279   -12.902 1.00 35.17  ? 47   GLN E CA    1 
ATOM   13499 C C     . GLN E 1 47  ? -52.053  9.337    -13.934 1.00 34.83  ? 47   GLN E C     1 
ATOM   13500 O O     . GLN E 1 47  ? -50.866  9.039    -13.851 1.00 38.45  ? 47   GLN E O     1 
ATOM   13501 C CB    . GLN E 1 47  ? -52.835  9.501    -11.585 1.00 38.98  ? 47   GLN E CB    1 
ATOM   13502 C CG    . GLN E 1 47  ? -53.211  10.351   -10.367 1.00 42.84  ? 47   GLN E CG    1 
ATOM   13503 C CD    . GLN E 1 47  ? -52.152  11.375   -10.028 1.00 51.94  ? 47   GLN E CD    1 
ATOM   13504 O OE1   . GLN E 1 47  ? -51.082  11.018   -9.535  1.00 58.17  ? 47   GLN E OE1   1 
ATOM   13505 N NE2   . GLN E 1 47  ? -52.418  12.638   -10.327 1.00 48.23  ? 47   GLN E NE2   1 
ATOM   13506 N N     . LEU E 1 48  ? -52.844  8.829    -14.886 1.00 30.34  ? 48   LEU E N     1 
ATOM   13507 C CA    . LEU E 1 48  ? -52.338  7.961    -15.944 1.00 30.95  ? 48   LEU E CA    1 
ATOM   13508 C C     . LEU E 1 48  ? -51.234  8.659    -16.742 1.00 31.36  ? 48   LEU E C     1 
ATOM   13509 O O     . LEU E 1 48  ? -50.427  7.964    -17.369 1.00 27.68  ? 48   LEU E O     1 
ATOM   13510 C CB    . LEU E 1 48  ? -53.458  7.463    -16.860 1.00 29.53  ? 48   LEU E CB    1 
ATOM   13511 C CG    . LEU E 1 48  ? -54.405  6.442    -16.217 1.00 31.67  ? 48   LEU E CG    1 
ATOM   13512 C CD1   . LEU E 1 48  ? -55.622  6.189    -17.109 1.00 26.57  ? 48   LEU E CD1   1 
ATOM   13513 C CD2   . LEU E 1 48  ? -53.634  5.143    -15.837 1.00 24.71  ? 48   LEU E CD2   1 
ATOM   13514 N N     . ILE E 1 49  ? -51.172  10.006   -16.695 1.00 26.56  ? 49   ILE E N     1 
ATOM   13515 C CA    . ILE E 1 49  ? -50.058  10.698   -17.339 1.00 28.15  ? 49   ILE E CA    1 
ATOM   13516 C C     . ILE E 1 49  ? -48.708  10.206   -16.784 1.00 30.53  ? 49   ILE E C     1 
ATOM   13517 O O     . ILE E 1 49  ? -47.708  10.173   -17.502 1.00 32.45  ? 49   ILE E O     1 
ATOM   13518 C CB    . ILE E 1 49  ? -50.178  12.235   -17.267 1.00 32.54  ? 49   ILE E CB    1 
ATOM   13519 C CG1   . ILE E 1 49  ? -49.202  12.907   -18.233 1.00 30.20  ? 49   ILE E CG1   1 
ATOM   13520 C CG2   . ILE E 1 49  ? -50.020  12.771   -15.824 1.00 28.05  ? 49   ILE E CG2   1 
ATOM   13521 C CD1   . ILE E 1 49  ? -49.465  14.395   -18.400 1.00 24.92  ? 49   ILE E CD1   1 
ATOM   13522 N N     . LYS E 1 50  ? -48.670  9.794    -15.517 1.00 31.69  ? 50   LYS E N     1 
ATOM   13523 C CA    . LYS E 1 50  ? -47.402  9.463    -14.872 1.00 37.20  ? 50   LYS E CA    1 
ATOM   13524 C C     . LYS E 1 50  ? -46.842  8.147    -15.383 1.00 41.09  ? 50   LYS E C     1 
ATOM   13525 O O     . LYS E 1 50  ? -45.655  7.903    -15.232 1.00 41.87  ? 50   LYS E O     1 
ATOM   13526 C CB    . LYS E 1 50  ? -47.510  9.415    -13.342 1.00 40.92  ? 50   LYS E CB    1 
ATOM   13527 C CG    . LYS E 1 50  ? -47.740  10.789   -12.779 1.00 49.51  ? 50   LYS E CG    1 
ATOM   13528 C CD    . LYS E 1 50  ? -48.087  10.725   -11.300 1.00 61.65  ? 50   LYS E CD    1 
ATOM   13529 C CE    . LYS E 1 50  ? -47.954  12.105   -10.753 1.00 69.53  ? 50   LYS E CE    1 
ATOM   13530 N NZ    . LYS E 1 50  ? -48.262  11.967   -9.327  1.00 71.16  ? 50   LYS E NZ    1 
ATOM   13531 N N     . THR E 1 51  ? -47.695  7.299    -15.976 1.00 45.85  ? 51   THR E N     1 
ATOM   13532 C CA    . THR E 1 51  ? -47.244  6.015    -16.494 1.00 38.07  ? 51   THR E CA    1 
ATOM   13533 C C     . THR E 1 51  ? -47.310  5.997    -18.027 1.00 38.49  ? 51   THR E C     1 
ATOM   13534 O O     . THR E 1 51  ? -47.205  4.940    -18.637 1.00 39.77  ? 51   THR E O     1 
ATOM   13535 C CB    . THR E 1 51  ? -48.024  4.878    -15.828 1.00 37.20  ? 51   THR E CB    1 
ATOM   13536 O OG1   . THR E 1 51  ? -49.379  5.324    -15.810 1.00 35.14  ? 51   THR E OG1   1 
ATOM   13537 C CG2   . THR E 1 51  ? -47.535  4.591    -14.419 1.00 32.91  ? 51   THR E CG2   1 
ATOM   13538 N N     . PHE E 1 52  ? -47.478  7.167    -18.654 1.00 35.63  ? 52   PHE E N     1 
ATOM   13539 C CA    . PHE E 1 52  ? -47.476  7.267    -20.102 1.00 31.15  ? 52   PHE E CA    1 
ATOM   13540 C C     . PHE E 1 52  ? -46.031  7.344    -20.603 1.00 33.77  ? 52   PHE E C     1 
ATOM   13541 O O     . PHE E 1 52  ? -45.505  8.439    -20.806 1.00 35.53  ? 52   PHE E O     1 
ATOM   13542 C CB    . PHE E 1 52  ? -48.323  8.461    -20.560 1.00 27.70  ? 52   PHE E CB    1 
ATOM   13543 C CG    . PHE E 1 52  ? -48.521  8.569    -22.061 1.00 29.62  ? 52   PHE E CG    1 
ATOM   13544 C CD1   . PHE E 1 52  ? -49.486  7.780    -22.704 1.00 33.93  ? 52   PHE E CD1   1 
ATOM   13545 C CD2   . PHE E 1 52  ? -47.756  9.432    -22.845 1.00 27.32  ? 52   PHE E CD2   1 
ATOM   13546 C CE1   . PHE E 1 52  ? -49.688  7.862    -24.085 1.00 32.52  ? 52   PHE E CE1   1 
ATOM   13547 C CE2   . PHE E 1 52  ? -47.958  9.506    -24.233 1.00 32.73  ? 52   PHE E CE2   1 
ATOM   13548 C CZ    . PHE E 1 52  ? -48.928  8.717    -24.856 1.00 28.46  ? 52   PHE E CZ    1 
ATOM   13549 N N     . THR E 1 53  ? -45.409  6.175    -20.838 1.00 31.19  ? 53   THR E N     1 
ATOM   13550 C CA    . THR E 1 53  ? -43.998  6.111    -21.203 1.00 28.35  ? 53   THR E CA    1 
ATOM   13551 C C     . THR E 1 53  ? -43.819  6.124    -22.716 1.00 30.53  ? 53   THR E C     1 
ATOM   13552 O O     . THR E 1 53  ? -42.722  6.430    -23.195 1.00 33.51  ? 53   THR E O     1 
ATOM   13553 C CB    . THR E 1 53  ? -43.335  4.858    -20.636 1.00 31.06  ? 53   THR E CB    1 
ATOM   13554 O OG1   . THR E 1 53  ? -44.041  3.821    -21.305 1.00 31.12  ? 53   THR E OG1   1 
ATOM   13555 C CG2   . THR E 1 53  ? -43.488  4.677    -19.131 1.00 27.73  ? 53   THR E CG2   1 
ATOM   13556 N N     . ALA E 1 54  ? -44.858  5.709    -23.463 1.00 27.79  ? 54   ALA E N     1 
ATOM   13557 C CA    . ALA E 1 54  ? -44.731  5.481    -24.900 1.00 27.57  ? 54   ALA E CA    1 
ATOM   13558 C C     . ALA E 1 54  ? -43.578  4.526    -25.216 1.00 26.98  ? 54   ALA E C     1 
ATOM   13559 O O     . ALA E 1 54  ? -42.986  4.627    -26.286 1.00 28.94  ? 54   ALA E O     1 
ATOM   13560 C CB    . ALA E 1 54  ? -44.547  6.768    -25.654 1.00 23.81  ? 54   ALA E CB    1 
ATOM   13561 N N     . ALA E 1 55  ? -43.279  3.598    -24.299 1.00 26.60  ? 55   ALA E N     1 
ATOM   13562 C CA    . ALA E 1 55  ? -42.111  2.733    -24.418 1.00 31.70  ? 55   ALA E CA    1 
ATOM   13563 C C     . ALA E 1 55  ? -42.181  1.857    -25.680 1.00 39.52  ? 55   ALA E C     1 
ATOM   13564 O O     . ALA E 1 55  ? -41.154  1.371    -26.131 1.00 38.78  ? 55   ALA E O     1 
ATOM   13565 C CB    . ALA E 1 55  ? -41.947  1.862    -23.168 1.00 28.67  ? 55   ALA E CB    1 
ATOM   13566 N N     . GLN E 1 56  ? -43.370  1.618    -26.261 1.00 36.23  ? 56   GLN E N     1 
ATOM   13567 C CA    . GLN E 1 56  ? -43.400  0.747    -27.423 1.00 32.65  ? 56   GLN E CA    1 
ATOM   13568 C C     . GLN E 1 56  ? -43.912  1.479    -28.647 1.00 31.56  ? 56   GLN E C     1 
ATOM   13569 O O     . GLN E 1 56  ? -44.267  0.858    -29.632 1.00 36.54  ? 56   GLN E O     1 
ATOM   13570 C CB    . GLN E 1 56  ? -44.195  -0.523   -27.164 1.00 33.10  ? 56   GLN E CB    1 
ATOM   13571 C CG    . GLN E 1 56  ? -43.367  -1.615   -26.510 1.00 40.58  ? 56   GLN E CG    1 
ATOM   13572 C CD    . GLN E 1 56  ? -44.148  -2.259   -25.393 1.00 57.67  ? 56   GLN E CD    1 
ATOM   13573 O OE1   . GLN E 1 56  ? -44.928  -3.189   -25.597 1.00 60.79  ? 56   GLN E OE1   1 
ATOM   13574 N NE2   . GLN E 1 56  ? -44.022  -1.681   -24.211 1.00 72.81  ? 56   GLN E NE2   1 
ATOM   13575 N N     . PHE E 1 57  ? -43.963  2.800    -28.588 1.00 30.09  ? 57   PHE E N     1 
ATOM   13576 C CA    . PHE E 1 57  ? -44.453  3.530    -29.742 1.00 29.78  ? 57   PHE E CA    1 
ATOM   13577 C C     . PHE E 1 57  ? -43.293  3.711    -30.713 1.00 38.18  ? 57   PHE E C     1 
ATOM   13578 O O     . PHE E 1 57  ? -42.287  4.321    -30.377 1.00 37.41  ? 57   PHE E O     1 
ATOM   13579 C CB    . PHE E 1 57  ? -45.008  4.892    -29.325 1.00 28.05  ? 57   PHE E CB    1 
ATOM   13580 C CG    . PHE E 1 57  ? -45.496  5.716    -30.505 1.00 27.81  ? 57   PHE E CG    1 
ATOM   13581 C CD1   . PHE E 1 57  ? -46.697  5.397    -31.146 1.00 27.99  ? 57   PHE E CD1   1 
ATOM   13582 C CD2   . PHE E 1 57  ? -44.783  6.829    -30.947 1.00 24.91  ? 57   PHE E CD2   1 
ATOM   13583 C CE1   . PHE E 1 57  ? -47.165  6.157    -32.213 1.00 26.43  ? 57   PHE E CE1   1 
ATOM   13584 C CE2   . PHE E 1 57  ? -45.247  7.595    -32.009 1.00 25.66  ? 57   PHE E CE2   1 
ATOM   13585 C CZ    . PHE E 1 57  ? -46.433  7.258    -32.647 1.00 27.74  ? 57   PHE E CZ    1 
ATOM   13586 N N     . ASP E 1 58  ? -43.450  3.199    -31.922 1.00 38.66  ? 58   ASP E N     1 
ATOM   13587 C CA    . ASP E 1 58  ? -42.458  3.392    -32.960 1.00 36.93  ? 58   ASP E CA    1 
ATOM   13588 C C     . ASP E 1 58  ? -43.165  3.888    -34.224 1.00 36.79  ? 58   ASP E C     1 
ATOM   13589 O O     . ASP E 1 58  ? -43.795  3.117    -34.952 1.00 39.02  ? 58   ASP E O     1 
ATOM   13590 C CB    . ASP E 1 58  ? -41.707  2.090    -33.181 1.00 42.42  ? 58   ASP E CB    1 
ATOM   13591 C CG    . ASP E 1 58  ? -40.589  2.108    -34.216 1.00 50.77  ? 58   ASP E CG    1 
ATOM   13592 O OD1   . ASP E 1 58  ? -40.444  3.116    -34.958 1.00 46.48  ? 58   ASP E OD1   1 
ATOM   13593 O OD2   . ASP E 1 58  ? -39.864  1.106    -34.267 1.00 63.03  ? 58   ASP E OD2   1 
ATOM   13594 N N     . ALA E 1 59  ? -43.061  5.192    -34.485 1.00 31.14  ? 59   ALA E N     1 
ATOM   13595 C CA    . ALA E 1 59  ? -43.811  5.802    -35.558 1.00 29.02  ? 59   ALA E CA    1 
ATOM   13596 C C     . ALA E 1 59  ? -43.385  5.193    -36.901 1.00 36.31  ? 59   ALA E C     1 
ATOM   13597 O O     . ALA E 1 59  ? -44.193  5.125    -37.827 1.00 29.86  ? 59   ALA E O     1 
ATOM   13598 C CB    . ALA E 1 59  ? -43.644  7.300    -35.529 1.00 27.21  ? 59   ALA E CB    1 
ATOM   13599 N N     . LYS E 1 60  ? -42.122  4.761    -37.012 1.00 37.33  ? 60   LYS E N     1 
ATOM   13600 C CA    . LYS E 1 60  ? -41.629  4.191    -38.262 1.00 37.58  ? 60   LYS E CA    1 
ATOM   13601 C C     . LYS E 1 60  ? -42.338  2.864    -38.527 1.00 37.03  ? 60   LYS E C     1 
ATOM   13602 O O     . LYS E 1 60  ? -42.745  2.605    -39.652 1.00 36.18  ? 60   LYS E O     1 
ATOM   13603 C CB    . LYS E 1 60  ? -40.112  3.992    -38.349 1.00 42.32  ? 60   LYS E CB    1 
ATOM   13604 C CG    . LYS E 1 60  ? -39.357  5.299    -38.479 1.00 64.19  ? 60   LYS E CG    1 
ATOM   13605 C CD    . LYS E 1 60  ? -37.891  5.410    -38.068 1.00 71.03  ? 60   LYS E CD    1 
ATOM   13606 C CE    . LYS E 1 60  ? -37.527  6.861    -38.263 1.00 77.72  ? 60   LYS E CE    1 
ATOM   13607 N NZ    . LYS E 1 60  ? -36.225  7.249    -37.723 1.00 73.09  ? 60   LYS E NZ    1 
ATOM   13608 N N     . LYS E 1 61  ? -42.510  2.044    -37.485 1.00 39.09  ? 61   LYS E N     1 
ATOM   13609 C CA    . LYS E 1 61  ? -43.211  0.776    -37.626 1.00 41.45  ? 61   LYS E CA    1 
ATOM   13610 C C     . LYS E 1 61  ? -44.668  1.022    -38.028 1.00 40.03  ? 61   LYS E C     1 
ATOM   13611 O O     . LYS E 1 61  ? -45.210  0.336    -38.885 1.00 40.36  ? 61   LYS E O     1 
ATOM   13612 C CB    . LYS E 1 61  ? -43.087  -0.129   -36.398 1.00 43.66  ? 61   LYS E CB    1 
ATOM   13613 C CG    . LYS E 1 61  ? -41.771  -0.918   -36.358 1.00 61.90  ? 61   LYS E CG    1 
ATOM   13614 C CD    . LYS E 1 61  ? -41.729  -2.138   -35.449 1.00 80.83  ? 61   LYS E CD    1 
ATOM   13615 C CE    . LYS E 1 61  ? -41.712  -1.788   -33.995 1.00 79.43  ? 61   LYS E CE    1 
ATOM   13616 N NZ    . LYS E 1 61  ? -41.218  -2.897   -33.204 1.00 82.18  ? 61   LYS E NZ    1 
ATOM   13617 N N     . ILE E 1 62  ? -45.295  2.031    -37.423 1.00 37.67  ? 62   ILE E N     1 
ATOM   13618 C CA    . ILE E 1 62  ? -46.682  2.329    -37.725 1.00 33.24  ? 62   ILE E CA    1 
ATOM   13619 C C     . ILE E 1 62  ? -46.821  2.793    -39.171 1.00 31.56  ? 62   ILE E C     1 
ATOM   13620 O O     . ILE E 1 62  ? -47.695  2.329    -39.891 1.00 32.01  ? 62   ILE E O     1 
ATOM   13621 C CB    . ILE E 1 62  ? -47.237  3.316    -36.698 1.00 34.10  ? 62   ILE E CB    1 
ATOM   13622 C CG1   . ILE E 1 62  ? -47.370  2.585    -35.353 1.00 37.07  ? 62   ILE E CG1   1 
ATOM   13623 C CG2   . ILE E 1 62  ? -48.557  3.919    -37.166 1.00 32.52  ? 62   ILE E CG2   1 
ATOM   13624 C CD1   . ILE E 1 62  ? -47.711  3.470    -34.181 1.00 37.51  ? 62   ILE E CD1   1 
ATOM   13625 N N     . ALA E 1 63  ? -45.925  3.665    -39.622 1.00 30.16  ? 63   ALA E N     1 
ATOM   13626 C CA    . ALA E 1 63  ? -45.987  4.149    -40.991 1.00 33.13  ? 63   ALA E CA    1 
ATOM   13627 C C     . ALA E 1 63  ? -45.751  3.002    -41.980 1.00 30.84  ? 63   ALA E C     1 
ATOM   13628 O O     . ALA E 1 63  ? -46.436  2.911    -43.000 1.00 28.67  ? 63   ALA E O     1 
ATOM   13629 C CB    . ALA E 1 63  ? -45.014  5.298    -41.200 1.00 29.06  ? 63   ALA E CB    1 
ATOM   13630 N N     . HIS E 1 64  ? -44.814  2.110    -41.656 1.00 32.94  ? 64   HIS E N     1 
ATOM   13631 C CA    . HIS E 1 64  ? -44.528  0.946    -42.487 1.00 39.67  ? 64   HIS E CA    1 
ATOM   13632 C C     . HIS E 1 64  ? -45.777  0.071    -42.624 1.00 38.75  ? 64   HIS E C     1 
ATOM   13633 O O     . HIS E 1 64  ? -46.167  -0.324   -43.728 1.00 37.13  ? 64   HIS E O     1 
ATOM   13634 C CB    . HIS E 1 64  ? -43.262  0.211    -42.029 1.00 43.99  ? 64   HIS E CB    1 
ATOM   13635 C CG    . HIS E 1 64  ? -42.837  -0.844   -43.006 1.00 75.53  ? 64   HIS E CG    1 
ATOM   13636 N ND1   . HIS E 1 64  ? -43.312  -2.142   -42.954 1.00 80.49  ? 64   HIS E ND1   1 
ATOM   13637 C CD2   . HIS E 1 64  ? -41.967  -0.797   -44.046 1.00 72.82  ? 64   HIS E CD2   1 
ATOM   13638 C CE1   . HIS E 1 64  ? -42.762  -2.852   -43.935 1.00 82.31  ? 64   HIS E CE1   1 
ATOM   13639 N NE2   . HIS E 1 64  ? -41.944  -2.051   -44.606 1.00 88.45  ? 64   HIS E NE2   1 
ATOM   13640 N N     . ALA E 1 65  ? -46.415  -0.212   -41.487 1.00 38.61  ? 65   ALA E N     1 
ATOM   13641 C CA    . ALA E 1 65  ? -47.615  -1.023   -41.473 1.00 37.86  ? 65   ALA E CA    1 
ATOM   13642 C C     . ALA E 1 65  ? -48.717  -0.370   -42.319 1.00 39.12  ? 65   ALA E C     1 
ATOM   13643 O O     . ALA E 1 65  ? -49.393  -1.046   -43.085 1.00 44.05  ? 65   ALA E O     1 
ATOM   13644 C CB    . ALA E 1 65  ? -48.021  -1.297   -40.034 1.00 27.51  ? 65   ALA E CB    1 
ATOM   13645 N N     . ALA E 1 66  ? -48.891  0.951    -42.202 1.00 33.00  ? 66   ALA E N     1 
ATOM   13646 C CA    . ALA E 1 66  ? -49.892  1.640    -42.999 1.00 29.44  ? 66   ALA E CA    1 
ATOM   13647 C C     . ALA E 1 66  ? -49.599  1.506    -44.499 1.00 31.51  ? 66   ALA E C     1 
ATOM   13648 O O     . ALA E 1 66  ? -50.505  1.280    -45.309 1.00 31.26  ? 66   ALA E O     1 
ATOM   13649 C CB    . ALA E 1 66  ? -49.963  3.079    -42.559 1.00 26.34  ? 66   ALA E CB    1 
ATOM   13650 N N     . LYS E 1 67  ? -48.318  1.637    -44.875 1.00 32.95  ? 67   LYS E N     1 
ATOM   13651 C CA    . LYS E 1 67  ? -47.921  1.493    -46.268 1.00 35.65  ? 67   LYS E CA    1 
ATOM   13652 C C     . LYS E 1 67  ? -48.240  0.079    -46.763 1.00 31.87  ? 67   LYS E C     1 
ATOM   13653 O O     . LYS E 1 67  ? -48.837  -0.074   -47.805 1.00 31.40  ? 67   LYS E O     1 
ATOM   13654 C CB    . LYS E 1 67  ? -46.451  1.859    -46.512 1.00 42.69  ? 67   LYS E CB    1 
ATOM   13655 C CG    . LYS E 1 67  ? -46.055  1.909    -47.982 1.00 46.47  ? 67   LYS E CG    1 
ATOM   13656 C CD    . LYS E 1 67  ? -44.641  2.420    -48.242 1.00 59.55  ? 67   LYS E CD    1 
ATOM   13657 C CE    . LYS E 1 67  ? -44.495  3.177    -49.530 1.00 61.52  ? 67   LYS E CE    1 
ATOM   13658 N NZ    . LYS E 1 67  ? -45.571  4.138    -49.794 1.00 64.49  ? 67   LYS E NZ    1 
ATOM   13659 N N     . ALA E 1 68  ? -47.887  -0.947   -45.980 1.00 31.43  ? 68   ALA E N     1 
ATOM   13660 C CA    . ALA E 1 68  ? -48.084  -2.347   -46.340 1.00 32.28  ? 68   ALA E CA    1 
ATOM   13661 C C     . ALA E 1 68  ? -49.574  -2.663   -46.504 1.00 35.22  ? 68   ALA E C     1 
ATOM   13662 O O     . ALA E 1 68  ? -49.936  -3.487   -47.330 1.00 40.15  ? 68   ALA E O     1 
ATOM   13663 C CB    . ALA E 1 68  ? -47.448  -3.277   -45.319 1.00 26.80  ? 68   ALA E CB    1 
ATOM   13664 N N     . VAL E 1 69  ? -50.439  -2.015   -45.721 1.00 31.46  ? 69   VAL E N     1 
ATOM   13665 C CA    . VAL E 1 69  ? -51.849  -2.333   -45.769 1.00 27.35  ? 69   VAL E CA    1 
ATOM   13666 C C     . VAL E 1 69  ? -52.485  -1.602   -46.963 1.00 30.64  ? 69   VAL E C     1 
ATOM   13667 O O     . VAL E 1 69  ? -53.667  -1.805   -47.244 1.00 31.77  ? 69   VAL E O     1 
ATOM   13668 C CB    . VAL E 1 69  ? -52.552  -2.016   -44.437 1.00 29.59  ? 69   VAL E CB    1 
ATOM   13669 C CG1   . VAL E 1 69  ? -52.942  -0.555   -44.306 1.00 31.70  ? 69   VAL E CG1   1 
ATOM   13670 C CG2   . VAL E 1 69  ? -53.844  -2.777   -44.300 1.00 43.07  ? 69   VAL E CG2   1 
ATOM   13671 N N     . GLY E 1 70  ? -51.713  -0.742   -47.657 1.00 26.78  ? 70   GLY E N     1 
ATOM   13672 C CA    . GLY E 1 70  ? -52.231  0.022    -48.781 1.00 25.55  ? 70   GLY E CA    1 
ATOM   13673 C C     . GLY E 1 70  ? -52.894  1.351    -48.403 1.00 29.98  ? 70   GLY E C     1 
ATOM   13674 O O     . GLY E 1 70  ? -53.548  1.976    -49.252 1.00 28.61  ? 70   GLY E O     1 
ATOM   13675 N N     . ALA E 1 71  ? -52.730  1.807    -47.144 1.00 25.77  ? 71   ALA E N     1 
ATOM   13676 C CA    . ALA E 1 71  ? -53.254  3.117    -46.742 1.00 24.90  ? 71   ALA E CA    1 
ATOM   13677 C C     . ALA E 1 71  ? -52.377  4.226    -47.323 1.00 24.11  ? 71   ALA E C     1 
ATOM   13678 O O     . ALA E 1 71  ? -51.177  4.034    -47.500 1.00 26.55  ? 71   ALA E O     1 
ATOM   13679 C CB    . ALA E 1 71  ? -53.342  3.213    -45.226 1.00 21.51  ? 71   ALA E CB    1 
ATOM   13680 N N     . LYS E 1 72  ? -52.970  5.386    -47.617 1.00 25.89  ? 72   LYS E N     1 
ATOM   13681 C CA    . LYS E 1 72  ? -52.230  6.515    -48.175 1.00 29.64  ? 72   LYS E CA    1 
ATOM   13682 C C     . LYS E 1 72  ? -52.205  7.694    -47.191 1.00 34.06  ? 72   LYS E C     1 
ATOM   13683 O O     . LYS E 1 72  ? -51.578  8.722    -47.462 1.00 37.58  ? 72   LYS E O     1 
ATOM   13684 C CB    . LYS E 1 72  ? -52.834  6.927    -49.526 1.00 31.84  ? 72   LYS E CB    1 
ATOM   13685 C CG    . LYS E 1 72  ? -52.677  5.897    -50.639 1.00 34.94  ? 72   LYS E CG    1 
ATOM   13686 C CD    . LYS E 1 72  ? -51.222  5.556    -50.939 1.00 38.33  ? 72   LYS E CD    1 
ATOM   13687 C CE    . LYS E 1 72  ? -50.936  4.544    -52.034 1.00 43.31  ? 72   LYS E CE    1 
ATOM   13688 N NZ    . LYS E 1 72  ? -51.508  5.022    -53.296 1.00 50.02  ? 72   LYS E NZ    1 
ATOM   13689 N N     . TYR E 1 73  ? -52.892  7.551    -46.047 1.00 30.89  ? 73   TYR E N     1 
ATOM   13690 C CA    . TYR E 1 73  ? -52.850  8.538    -44.983 1.00 29.59  ? 73   TYR E CA    1 
ATOM   13691 C C     . TYR E 1 73  ? -53.155  7.871    -43.649 1.00 30.65  ? 73   TYR E C     1 
ATOM   13692 O O     . TYR E 1 73  ? -53.672  6.755    -43.624 1.00 35.58  ? 73   TYR E O     1 
ATOM   13693 C CB    . TYR E 1 73  ? -53.817  9.690    -45.250 1.00 26.83  ? 73   TYR E CB    1 
ATOM   13694 C CG    . TYR E 1 73  ? -55.316  9.428    -45.321 1.00 26.79  ? 73   TYR E CG    1 
ATOM   13695 C CD1   . TYR E 1 73  ? -55.866  8.609    -46.313 1.00 23.46  ? 73   TYR E CD1   1 
ATOM   13696 C CD2   . TYR E 1 73  ? -56.199  10.070   -44.445 1.00 26.05  ? 73   TYR E CD2   1 
ATOM   13697 C CE1   . TYR E 1 73  ? -57.240  8.443    -46.425 1.00 21.69  ? 73   TYR E CE1   1 
ATOM   13698 C CE2   . TYR E 1 73  ? -57.579  9.904    -44.533 1.00 24.74  ? 73   TYR E CE2   1 
ATOM   13699 C CZ    . TYR E 1 73  ? -58.096  9.094    -45.536 1.00 24.62  ? 73   TYR E CZ    1 
ATOM   13700 O OH    . TYR E 1 73  ? -59.452  8.955    -45.646 1.00 25.04  ? 73   TYR E OH    1 
ATOM   13701 N N     . ILE E 1 74  ? -52.800  8.561    -42.556 1.00 27.34  ? 74   ILE E N     1 
ATOM   13702 C CA    . ILE E 1 74  ? -53.034  8.088    -41.201 1.00 27.45  ? 74   ILE E CA    1 
ATOM   13703 C C     . ILE E 1 74  ? -53.648  9.242    -40.407 1.00 29.48  ? 74   ILE E C     1 
ATOM   13704 O O     . ILE E 1 74  ? -53.146  10.369   -40.453 1.00 29.21  ? 74   ILE E O     1 
ATOM   13705 C CB    . ILE E 1 74  ? -51.733  7.623    -40.527 1.00 25.39  ? 74   ILE E CB    1 
ATOM   13706 C CG1   . ILE E 1 74  ? -50.943  6.624    -41.391 1.00 23.21  ? 74   ILE E CG1   1 
ATOM   13707 C CG2   . ILE E 1 74  ? -52.041  7.092    -39.126 1.00 26.75  ? 74   ILE E CG2   1 
ATOM   13708 C CD1   . ILE E 1 74  ? -49.612  6.226    -40.767 1.00 21.84  ? 74   ILE E CD1   1 
ATOM   13709 N N     . VAL E 1 75  ? -54.759  8.947    -39.718 1.00 26.71  ? 75   VAL E N     1 
ATOM   13710 C CA    . VAL E 1 75  ? -55.360  9.883    -38.799 1.00 25.14  ? 75   VAL E CA    1 
ATOM   13711 C C     . VAL E 1 75  ? -54.999  9.427    -37.388 1.00 29.31  ? 75   VAL E C     1 
ATOM   13712 O O     . VAL E 1 75  ? -55.429  8.345    -36.974 1.00 28.25  ? 75   VAL E O     1 
ATOM   13713 C CB    . VAL E 1 75  ? -56.877  9.908    -39.003 1.00 25.22  ? 75   VAL E CB    1 
ATOM   13714 C CG1   . VAL E 1 75  ? -57.546  10.917   -38.065 1.00 25.74  ? 75   VAL E CG1   1 
ATOM   13715 C CG2   . VAL E 1 75  ? -57.232  10.249   -40.440 1.00 23.13  ? 75   VAL E CG2   1 
ATOM   13716 N N     . LEU E 1 76  ? -54.199  10.253   -36.672 1.00 27.06  ? 76   LEU E N     1 
ATOM   13717 C CA    . LEU E 1 76  ? -53.787  9.957    -35.301 1.00 24.54  ? 76   LEU E CA    1 
ATOM   13718 C C     . LEU E 1 76  ? -54.539  10.863   -34.326 1.00 24.44  ? 76   LEU E C     1 
ATOM   13719 O O     . LEU E 1 76  ? -54.677  12.072   -34.567 1.00 25.56  ? 76   LEU E O     1 
ATOM   13720 C CB    . LEU E 1 76  ? -52.276  10.118   -35.173 1.00 25.42  ? 76   LEU E CB    1 
ATOM   13721 C CG    . LEU E 1 76  ? -51.686  9.870    -33.780 1.00 30.03  ? 76   LEU E CG    1 
ATOM   13722 C CD1   . LEU E 1 76  ? -51.986  8.479    -33.213 1.00 25.93  ? 76   LEU E CD1   1 
ATOM   13723 C CD2   . LEU E 1 76  ? -50.178  10.089   -33.807 1.00 27.79  ? 76   LEU E CD2   1 
ATOM   13724 N N     . THR E 1 77  ? -55.038  10.278   -33.222 1.00 21.54  ? 77   THR E N     1 
ATOM   13725 C CA    . THR E 1 77  ? -55.656  11.079   -32.176 1.00 24.83  ? 77   THR E CA    1 
ATOM   13726 C C     . THR E 1 77  ? -54.581  11.956   -31.508 1.00 27.28  ? 77   THR E C     1 
ATOM   13727 O O     . THR E 1 77  ? -53.741  11.441   -30.776 1.00 30.67  ? 77   THR E O     1 
ATOM   13728 C CB    . THR E 1 77  ? -56.348  10.175   -31.156 1.00 24.78  ? 77   THR E CB    1 
ATOM   13729 O OG1   . THR E 1 77  ? -55.416  9.208    -30.680 1.00 25.69  ? 77   THR E OG1   1 
ATOM   13730 C CG2   . THR E 1 77  ? -57.594  9.509    -31.708 1.00 21.88  ? 77   THR E CG2   1 
ATOM   13731 N N     . THR E 1 78  ? -54.598  13.277   -31.756 1.00 26.02  ? 78   THR E N     1 
ATOM   13732 C CA    . THR E 1 78  ? -53.611  14.149   -31.120 1.00 30.01  ? 78   THR E CA    1 
ATOM   13733 C C     . THR E 1 78  ? -54.112  14.608   -29.743 1.00 30.48  ? 78   THR E C     1 
ATOM   13734 O O     . THR E 1 78  ? -53.300  14.966   -28.886 1.00 29.90  ? 78   THR E O     1 
ATOM   13735 C CB    . THR E 1 78  ? -53.253  15.356   -31.991 1.00 29.99  ? 78   THR E CB    1 
ATOM   13736 O OG1   . THR E 1 78  ? -54.402  16.220   -31.987 1.00 26.54  ? 78   THR E OG1   1 
ATOM   13737 C CG2   . THR E 1 78  ? -52.795  14.953   -33.386 1.00 25.28  ? 78   THR E CG2   1 
ATOM   13738 N N     . LYS E 1 79  ? -55.446  14.617   -29.561 1.00 29.32  ? 79   LYS E N     1 
ATOM   13739 C CA    . LYS E 1 79  ? -56.098  14.879   -28.289 1.00 30.05  ? 79   LYS E CA    1 
ATOM   13740 C C     . LYS E 1 79  ? -57.528  14.362   -28.374 1.00 26.01  ? 79   LYS E C     1 
ATOM   13741 O O     . LYS E 1 79  ? -58.293  14.831   -29.225 1.00 26.65  ? 79   LYS E O     1 
ATOM   13742 C CB    . LYS E 1 79  ? -56.150  16.392   -27.987 1.00 30.04  ? 79   LYS E CB    1 
ATOM   13743 C CG    . LYS E 1 79  ? -56.641  16.754   -26.582 1.00 29.69  ? 79   LYS E CG    1 
ATOM   13744 C CD    . LYS E 1 79  ? -57.408  18.071   -26.441 1.00 31.28  ? 79   LYS E CD    1 
ATOM   13745 C CE    . LYS E 1 79  ? -58.737  18.070   -27.069 1.00 27.77  ? 79   LYS E CE    1 
ATOM   13746 N NZ    . LYS E 1 79  ? -59.497  19.316   -26.905 1.00 30.19  ? 79   LYS E NZ    1 
ATOM   13747 N N     . HIS E 1 80  ? -57.880  13.401   -27.503 1.00 26.10  ? 80   HIS E N     1 
ATOM   13748 C CA    . HIS E 1 80  ? -59.246  12.865   -27.487 1.00 27.99  ? 80   HIS E CA    1 
ATOM   13749 C C     . HIS E 1 80  ? -60.088  13.604   -26.429 1.00 30.10  ? 80   HIS E C     1 
ATOM   13750 O O     . HIS E 1 80  ? -59.639  14.597   -25.858 1.00 28.76  ? 80   HIS E O     1 
ATOM   13751 C CB    . HIS E 1 80  ? -59.190  11.336   -27.371 1.00 26.32  ? 80   HIS E CB    1 
ATOM   13752 C CG    . HIS E 1 80  ? -60.369  10.667   -28.003 1.00 26.41  ? 80   HIS E CG    1 
ATOM   13753 N ND1   . HIS E 1 80  ? -61.547  10.416   -27.328 1.00 26.46  ? 80   HIS E ND1   1 
ATOM   13754 C CD2   . HIS E 1 80  ? -60.555  10.224   -29.262 1.00 23.88  ? 80   HIS E CD2   1 
ATOM   13755 C CE1   . HIS E 1 80  ? -62.411  9.836    -28.144 1.00 24.81  ? 80   HIS E CE1   1 
ATOM   13756 N NE2   . HIS E 1 80  ? -61.825  9.709    -29.326 1.00 26.09  ? 80   HIS E NE2   1 
ATOM   13757 N N     . HIS E 1 81  ? -61.300  13.124   -26.134 1.00 29.60  ? 81   HIS E N     1 
ATOM   13758 C CA    . HIS E 1 81  ? -62.155  13.785   -25.160 1.00 29.46  ? 81   HIS E CA    1 
ATOM   13759 C C     . HIS E 1 81  ? -61.453  13.926   -23.802 1.00 30.00  ? 81   HIS E C     1 
ATOM   13760 O O     . HIS E 1 81  ? -61.646  14.921   -23.104 1.00 32.79  ? 81   HIS E O     1 
ATOM   13761 C CB    . HIS E 1 81  ? -63.491  13.056   -24.997 1.00 30.17  ? 81   HIS E CB    1 
ATOM   13762 C CG    . HIS E 1 81  ? -64.226  12.894   -26.286 1.00 35.56  ? 81   HIS E CG    1 
ATOM   13763 N ND1   . HIS E 1 81  ? -64.429  13.946   -27.155 1.00 33.17  ? 81   HIS E ND1   1 
ATOM   13764 C CD2   . HIS E 1 81  ? -64.806  11.806   -26.862 1.00 32.20  ? 81   HIS E CD2   1 
ATOM   13765 C CE1   . HIS E 1 81  ? -65.103  13.508   -28.220 1.00 29.96  ? 81   HIS E CE1   1 
ATOM   13766 N NE2   . HIS E 1 81  ? -65.349  12.217   -28.052 1.00 30.74  ? 81   HIS E NE2   1 
ATOM   13767 N N     . GLU E 1 82  ? -60.653  12.930   -23.411 1.00 24.85  ? 82   GLU E N     1 
ATOM   13768 C CA    . GLU E 1 82  ? -59.983  12.993   -22.126 1.00 24.93  ? 82   GLU E CA    1 
ATOM   13769 C C     . GLU E 1 82  ? -59.104  14.255   -22.041 1.00 29.49  ? 82   GLU E C     1 
ATOM   13770 O O     . GLU E 1 82  ? -58.718  14.657   -20.949 1.00 27.51  ? 82   GLU E O     1 
ATOM   13771 C CB    . GLU E 1 82  ? -59.115  11.754   -21.890 1.00 27.86  ? 82   GLU E CB    1 
ATOM   13772 C CG    . GLU E 1 82  ? -58.075  11.542   -22.999 1.00 25.24  ? 82   GLU E CG    1 
ATOM   13773 C CD    . GLU E 1 82  ? -57.045  10.456   -22.814 1.00 27.18  ? 82   GLU E CD    1 
ATOM   13774 O OE1   . GLU E 1 82  ? -57.225  9.549    -21.941 1.00 27.03  ? 82   GLU E OE1   1 
ATOM   13775 O OE2   . GLU E 1 82  ? -56.016  10.535   -23.564 1.00 26.66  ? 82   GLU E OE2   1 
ATOM   13776 N N     . GLY E 1 83  ? -58.709  14.836   -23.184 1.00 26.28  ? 83   GLY E N     1 
ATOM   13777 C CA    . GLY E 1 83  ? -58.109  16.160   -23.191 1.00 30.19  ? 83   GLY E CA    1 
ATOM   13778 C C     . GLY E 1 83  ? -56.588  16.146   -23.044 1.00 32.89  ? 83   GLY E C     1 
ATOM   13779 O O     . GLY E 1 83  ? -55.989  17.209   -22.903 1.00 35.73  ? 83   GLY E O     1 
ATOM   13780 N N     . PHE E 1 84  ? -55.958  14.955   -23.079 1.00 32.25  ? 84   PHE E N     1 
ATOM   13781 C CA    . PHE E 1 84  ? -54.505  14.834   -23.016 1.00 27.32  ? 84   PHE E CA    1 
ATOM   13782 C C     . PHE E 1 84  ? -53.883  14.977   -24.405 1.00 29.48  ? 84   PHE E C     1 
ATOM   13783 O O     . PHE E 1 84  ? -54.326  14.344   -25.353 1.00 34.79  ? 84   PHE E O     1 
ATOM   13784 C CB    . PHE E 1 84  ? -54.199  13.474   -22.405 1.00 27.67  ? 84   PHE E CB    1 
ATOM   13785 C CG    . PHE E 1 84  ? -52.729  13.102   -22.508 1.00 31.27  ? 84   PHE E CG    1 
ATOM   13786 C CD1   . PHE E 1 84  ? -51.787  13.707   -21.678 1.00 30.69  ? 84   PHE E CD1   1 
ATOM   13787 C CD2   . PHE E 1 84  ? -52.284  12.152   -23.427 1.00 27.03  ? 84   PHE E CD2   1 
ATOM   13788 C CE1   . PHE E 1 84  ? -50.436  13.360   -21.753 1.00 32.55  ? 84   PHE E CE1   1 
ATOM   13789 C CE2   . PHE E 1 84  ? -50.935  11.820   -23.514 1.00 32.44  ? 84   PHE E CE2   1 
ATOM   13790 C CZ    . PHE E 1 84  ? -50.012  12.437   -22.685 1.00 34.17  ? 84   PHE E CZ    1 
ATOM   13791 N N     . PHE E 1 85  ? -52.827  15.781   -24.526 1.00 29.61  ? 85   PHE E N     1 
ATOM   13792 C CA    . PHE E 1 85  ? -52.244  16.093   -25.822 1.00 29.14  ? 85   PHE E CA    1 
ATOM   13793 C C     . PHE E 1 85  ? -50.990  15.265   -26.071 1.00 33.46  ? 85   PHE E C     1 
ATOM   13794 O O     . PHE E 1 85  ? -50.090  15.193   -25.228 1.00 33.21  ? 85   PHE E O     1 
ATOM   13795 C CB    . PHE E 1 85  ? -51.815  17.560   -25.887 1.00 27.94  ? 85   PHE E CB    1 
ATOM   13796 C CG    . PHE E 1 85  ? -52.907  18.597   -25.685 1.00 25.74  ? 85   PHE E CG    1 
ATOM   13797 C CD1   . PHE E 1 85  ? -53.253  19.014   -24.404 1.00 25.17  ? 85   PHE E CD1   1 
ATOM   13798 C CD2   . PHE E 1 85  ? -53.557  19.170   -26.776 1.00 25.00  ? 85   PHE E CD2   1 
ATOM   13799 C CE1   . PHE E 1 85  ? -54.282  19.952   -24.218 1.00 26.68  ? 85   PHE E CE1   1 
ATOM   13800 C CE2   . PHE E 1 85  ? -54.577  20.107   -26.594 1.00 26.56  ? 85   PHE E CE2   1 
ATOM   13801 C CZ    . PHE E 1 85  ? -54.939  20.503   -25.305 1.00 25.59  ? 85   PHE E CZ    1 
ATOM   13802 N N     . LEU E 1 86  ? -50.922  14.676   -27.269 1.00 36.96  ? 86   LEU E N     1 
ATOM   13803 C CA    . LEU E 1 86  ? -49.810  13.805   -27.620 1.00 38.00  ? 86   LEU E CA    1 
ATOM   13804 C C     . LEU E 1 86  ? -48.648  14.603   -28.213 1.00 38.31  ? 86   LEU E C     1 
ATOM   13805 O O     . LEU E 1 86  ? -47.718  14.031   -28.756 1.00 40.95  ? 86   LEU E O     1 
ATOM   13806 C CB    . LEU E 1 86  ? -50.290  12.694   -28.550 1.00 34.40  ? 86   LEU E CB    1 
ATOM   13807 C CG    . LEU E 1 86  ? -50.863  11.452   -27.849 1.00 38.30  ? 86   LEU E CG    1 
ATOM   13808 C CD1   . LEU E 1 86  ? -52.239  11.689   -27.277 1.00 30.60  ? 86   LEU E CD1   1 
ATOM   13809 C CD2   . LEU E 1 86  ? -50.925  10.341   -28.882 1.00 33.95  ? 86   LEU E CD2   1 
ATOM   13810 N N     . TYR E 1 87  ? -48.708  15.930   -28.118 1.00 35.58  ? 87   TYR E N     1 
ATOM   13811 C CA    . TYR E 1 87  ? -47.639  16.773   -28.645 1.00 37.23  ? 87   TYR E CA    1 
ATOM   13812 C C     . TYR E 1 87  ? -47.278  17.881   -27.647 1.00 39.16  ? 87   TYR E C     1 
ATOM   13813 O O     . TYR E 1 87  ? -47.955  18.062   -26.641 1.00 35.90  ? 87   TYR E O     1 
ATOM   13814 C CB    . TYR E 1 87  ? -48.071  17.364   -29.989 1.00 29.52  ? 87   TYR E CB    1 
ATOM   13815 C CG    . TYR E 1 87  ? -49.351  18.190   -29.956 1.00 32.48  ? 87   TYR E CG    1 
ATOM   13816 C CD1   . TYR E 1 87  ? -50.611  17.583   -29.917 1.00 31.18  ? 87   TYR E CD1   1 
ATOM   13817 C CD2   . TYR E 1 87  ? -49.307  19.589   -29.994 1.00 33.42  ? 87   TYR E CD2   1 
ATOM   13818 C CE1   . TYR E 1 87  ? -51.783  18.328   -29.903 1.00 29.12  ? 87   TYR E CE1   1 
ATOM   13819 C CE2   . TYR E 1 87  ? -50.470  20.348   -30.009 1.00 34.22  ? 87   TYR E CE2   1 
ATOM   13820 C CZ    . TYR E 1 87  ? -51.713  19.718   -29.961 1.00 35.66  ? 87   TYR E CZ    1 
ATOM   13821 O OH    . TYR E 1 87  ? -52.859  20.479   -29.972 1.00 36.17  ? 87   TYR E OH    1 
ATOM   13822 N N     . ASP E 1 88  ? -46.229  18.649   -27.961 1.00 36.06  ? 88   ASP E N     1 
ATOM   13823 C CA    . ASP E 1 88  ? -45.786  19.739   -27.123 1.00 30.86  ? 88   ASP E CA    1 
ATOM   13824 C C     . ASP E 1 88  ? -46.696  20.941   -27.343 1.00 29.43  ? 88   ASP E C     1 
ATOM   13825 O O     . ASP E 1 88  ? -46.636  21.590   -28.392 1.00 26.87  ? 88   ASP E O     1 
ATOM   13826 C CB    . ASP E 1 88  ? -44.351  20.101   -27.467 1.00 41.32  ? 88   ASP E CB    1 
ATOM   13827 C CG    . ASP E 1 88  ? -43.699  21.180   -26.604 1.00 43.24  ? 88   ASP E CG    1 
ATOM   13828 O OD1   . ASP E 1 88  ? -44.420  21.915   -25.865 1.00 40.67  ? 88   ASP E OD1   1 
ATOM   13829 O OD2   . ASP E 1 88  ? -42.471  21.257   -26.665 1.00 44.11  ? 88   ASP E OD2   1 
ATOM   13830 N N     . THR E 1 89  ? -47.504  21.278   -26.333 1.00 27.36  ? 89   THR E N     1 
ATOM   13831 C CA    . THR E 1 89  ? -48.453  22.369   -26.524 1.00 31.11  ? 89   THR E CA    1 
ATOM   13832 C C     . THR E 1 89  ? -47.796  23.728   -26.258 1.00 34.98  ? 89   THR E C     1 
ATOM   13833 O O     . THR E 1 89  ? -48.499  24.732   -26.253 1.00 34.25  ? 89   THR E O     1 
ATOM   13834 C CB    . THR E 1 89  ? -49.696  22.187   -25.656 1.00 34.46  ? 89   THR E CB    1 
ATOM   13835 O OG1   . THR E 1 89  ? -49.275  22.275   -24.295 1.00 29.00  ? 89   THR E OG1   1 
ATOM   13836 C CG2   . THR E 1 89  ? -50.365  20.841   -25.884 1.00 32.62  ? 89   THR E CG2   1 
ATOM   13837 N N     . LYS E 1 90  ? -46.470  23.746   -25.993 1.00 35.48  ? 90   LYS E N     1 
ATOM   13838 C CA    . LYS E 1 90  ? -45.677  24.971   -25.896 1.00 41.88  ? 90   LYS E CA    1 
ATOM   13839 C C     . LYS E 1 90  ? -46.253  25.916   -24.834 1.00 38.48  ? 90   LYS E C     1 
ATOM   13840 O O     . LYS E 1 90  ? -46.430  27.105   -25.106 1.00 39.43  ? 90   LYS E O     1 
ATOM   13841 C CB    . LYS E 1 90  ? -45.617  25.714   -27.240 1.00 40.20  ? 90   LYS E CB    1 
ATOM   13842 C CG    . LYS E 1 90  ? -45.048  24.860   -28.359 1.00 46.83  ? 90   LYS E CG    1 
ATOM   13843 C CD    . LYS E 1 90  ? -44.307  25.518   -29.512 1.00 62.12  ? 90   LYS E CD    1 
ATOM   13844 C CE    . LYS E 1 90  ? -42.901  25.040   -29.228 1.00 78.14  ? 90   LYS E CE    1 
ATOM   13845 N NZ    . LYS E 1 90  ? -41.858  25.773   -29.950 1.00 76.05  ? 90   LYS E NZ    1 
ATOM   13846 N N     . GLY E 1 91  ? -46.627  25.366   -23.670 1.00 32.69  ? 91   GLY E N     1 
ATOM   13847 C CA    . GLY E 1 91  ? -47.129  26.148   -22.568 1.00 34.77  ? 91   GLY E CA    1 
ATOM   13848 C C     . GLY E 1 91  ? -48.652  26.257   -22.503 1.00 38.65  ? 91   GLY E C     1 
ATOM   13849 O O     . GLY E 1 91  ? -49.168  26.705   -21.498 1.00 40.34  ? 91   GLY E O     1 
ATOM   13850 N N     . LEU E 1 92  ? -49.391  25.839   -23.536 1.00 38.95  ? 92   LEU E N     1 
ATOM   13851 C CA    . LEU E 1 92  ? -50.838  25.944   -23.449 1.00 32.58  ? 92   LEU E CA    1 
ATOM   13852 C C     . LEU E 1 92  ? -51.387  25.067   -22.321 1.00 34.68  ? 92   LEU E C     1 
ATOM   13853 O O     . LEU E 1 92  ? -52.363  25.436   -21.680 1.00 33.08  ? 92   LEU E O     1 
ATOM   13854 C CB    . LEU E 1 92  ? -51.492  25.587   -24.777 1.00 36.69  ? 92   LEU E CB    1 
ATOM   13855 C CG    . LEU E 1 92  ? -53.023  25.619   -24.743 1.00 48.04  ? 92   LEU E CG    1 
ATOM   13856 C CD1   . LEU E 1 92  ? -53.548  27.059   -24.622 1.00 46.02  ? 92   LEU E CD1   1 
ATOM   13857 C CD2   . LEU E 1 92  ? -53.618  24.861   -25.912 1.00 44.69  ? 92   LEU E CD2   1 
ATOM   13858 N N     . SER E 1 93  ? -50.784  23.885   -22.087 1.00 28.66  ? 93   SER E N     1 
ATOM   13859 C CA    . SER E 1 93  ? -51.323  22.978   -21.097 1.00 29.55  ? 93   SER E CA    1 
ATOM   13860 C C     . SER E 1 93  ? -50.192  22.173   -20.465 1.00 32.00  ? 93   SER E C     1 
ATOM   13861 O O     . SER E 1 93  ? -49.220  21.861   -21.145 1.00 38.31  ? 93   SER E O     1 
ATOM   13862 C CB    . SER E 1 93  ? -52.353  22.050   -21.751 1.00 29.31  ? 93   SER E CB    1 
ATOM   13863 O OG    . SER E 1 93  ? -52.699  20.983   -20.862 1.00 28.79  ? 93   SER E OG    1 
ATOM   13864 N N     . ASP E 1 94  ? -50.361  21.789   -19.193 1.00 31.15  ? 94   ASP E N     1 
ATOM   13865 C CA    . ASP E 1 94  ? -49.398  20.873   -18.589 1.00 38.78  ? 94   ASP E CA    1 
ATOM   13866 C C     . ASP E 1 94  ? -49.823  19.409   -18.779 1.00 35.76  ? 94   ASP E C     1 
ATOM   13867 O O     . ASP E 1 94  ? -49.111  18.491   -18.357 1.00 36.71  ? 94   ASP E O     1 
ATOM   13868 C CB    . ASP E 1 94  ? -49.092  21.189   -17.129 1.00 44.32  ? 94   ASP E CB    1 
ATOM   13869 C CG    . ASP E 1 94  ? -50.227  20.948   -16.149 1.00 52.36  ? 94   ASP E CG    1 
ATOM   13870 O OD1   . ASP E 1 94  ? -51.375  20.784   -16.616 1.00 52.35  ? 94   ASP E OD1   1 
ATOM   13871 O OD2   . ASP E 1 94  ? -49.942  20.876   -14.924 1.00 52.04  ? 94   ASP E OD2   1 
ATOM   13872 N N     . PHE E 1 95  ? -51.006  19.194   -19.355 1.00 33.30  ? 95   PHE E N     1 
ATOM   13873 C CA    . PHE E 1 95  ? -51.528  17.841   -19.522 1.00 35.96  ? 95   PHE E CA    1 
ATOM   13874 C C     . PHE E 1 95  ? -51.145  17.339   -20.925 1.00 32.91  ? 95   PHE E C     1 
ATOM   13875 O O     . PHE E 1 95  ? -52.010  17.181   -21.800 1.00 32.67  ? 95   PHE E O     1 
ATOM   13876 C CB    . PHE E 1 95  ? -53.039  17.926   -19.290 1.00 28.50  ? 95   PHE E CB    1 
ATOM   13877 C CG    . PHE E 1 95  ? -53.727  16.590   -19.034 1.00 30.51  ? 95   PHE E CG    1 
ATOM   13878 C CD1   . PHE E 1 95  ? -53.212  15.682   -18.112 1.00 26.42  ? 95   PHE E CD1   1 
ATOM   13879 C CD2   . PHE E 1 95  ? -54.914  16.263   -19.708 1.00 29.27  ? 95   PHE E CD2   1 
ATOM   13880 C CE1   . PHE E 1 95  ? -53.859  14.474   -17.869 1.00 28.49  ? 95   PHE E CE1   1 
ATOM   13881 C CE2   . PHE E 1 95  ? -55.577  15.066   -19.452 1.00 27.07  ? 95   PHE E CE2   1 
ATOM   13882 C CZ    . PHE E 1 95  ? -55.044  14.172   -18.539 1.00 30.24  ? 95   PHE E CZ    1 
ATOM   13883 N N     . ASP E 1 96  ? -49.839  17.218   -21.176 1.00 27.77  ? 96   ASP E N     1 
ATOM   13884 C CA    . ASP E 1 96  ? -49.352  16.877   -22.501 1.00 30.23  ? 96   ASP E CA    1 
ATOM   13885 C C     . ASP E 1 96  ? -48.152  15.946   -22.351 1.00 33.35  ? 96   ASP E C     1 
ATOM   13886 O O     . ASP E 1 96  ? -47.659  15.708   -21.243 1.00 33.01  ? 96   ASP E O     1 
ATOM   13887 C CB    . ASP E 1 96  ? -49.118  18.104   -23.370 1.00 31.01  ? 96   ASP E CB    1 
ATOM   13888 C CG    . ASP E 1 96  ? -47.842  18.913   -23.131 1.00 35.47  ? 96   ASP E CG    1 
ATOM   13889 O OD1   . ASP E 1 96  ? -46.943  18.416   -22.400 1.00 36.62  ? 96   ASP E OD1   1 
ATOM   13890 O OD2   . ASP E 1 96  ? -47.737  20.043   -23.696 1.00 37.33  ? 96   ASP E OD2   1 
ATOM   13891 N N     . VAL E 1 97  ? -47.670  15.438   -23.483 1.00 32.46  ? 97   VAL E N     1 
ATOM   13892 C CA    . VAL E 1 97  ? -46.698  14.363   -23.453 1.00 33.83  ? 97   VAL E CA    1 
ATOM   13893 C C     . VAL E 1 97  ? -45.354  14.865   -22.909 1.00 38.41  ? 97   VAL E C     1 
ATOM   13894 O O     . VAL E 1 97  ? -44.571  14.061   -22.394 1.00 40.62  ? 97   VAL E O     1 
ATOM   13895 C CB    . VAL E 1 97  ? -46.585  13.779   -24.876 1.00 27.00  ? 97   VAL E CB    1 
ATOM   13896 C CG1   . VAL E 1 97  ? -46.046  14.812   -25.851 1.00 21.74  ? 97   VAL E CG1   1 
ATOM   13897 C CG2   . VAL E 1 97  ? -45.736  12.511   -24.852 1.00 26.53  ? 97   VAL E CG2   1 
ATOM   13898 N N     . MET E 1 98  ? -45.091  16.182   -23.011 1.00 39.26  ? 98   MET E N     1 
ATOM   13899 C CA    . MET E 1 98  ? -43.846  16.723   -22.472 1.00 40.28  ? 98   MET E CA    1 
ATOM   13900 C C     . MET E 1 98  ? -43.826  16.673   -20.942 1.00 43.34  ? 98   MET E C     1 
ATOM   13901 O O     . MET E 1 98  ? -42.750  16.697   -20.346 1.00 44.40  ? 98   MET E O     1 
ATOM   13902 C CB    . MET E 1 98  ? -43.541  18.136   -22.972 1.00 39.09  ? 98   MET E CB    1 
ATOM   13903 C CG    . MET E 1 98  ? -43.498  18.255   -24.500 1.00 46.28  ? 98   MET E CG    1 
ATOM   13904 S SD    . MET E 1 98  ? -42.450  17.058   -25.362 1.00 53.86  ? 98   MET E SD    1 
ATOM   13905 C CE    . MET E 1 98  ? -40.757  17.407   -24.863 1.00 46.70  ? 98   MET E CE    1 
ATOM   13906 N N     . HIS E 1 99  ? -44.994  16.497   -20.304 1.00 34.86  ? 99   HIS E N     1 
ATOM   13907 C CA    . HIS E 1 99  ? -45.070  16.377   -18.860 1.00 32.66  ? 99   HIS E CA    1 
ATOM   13908 C C     . HIS E 1 99  ? -45.265  14.925   -18.454 1.00 33.74  ? 99   HIS E C     1 
ATOM   13909 O O     . HIS E 1 99  ? -45.623  14.645   -17.316 1.00 36.68  ? 99   HIS E O     1 
ATOM   13910 C CB    . HIS E 1 99  ? -46.194  17.267   -18.304 1.00 34.82  ? 99   HIS E CB    1 
ATOM   13911 C CG    . HIS E 1 99  ? -45.892  18.710   -18.532 1.00 41.58  ? 99   HIS E CG    1 
ATOM   13912 N ND1   . HIS E 1 99  ? -46.041  19.313   -19.769 1.00 45.20  ? 99   HIS E ND1   1 
ATOM   13913 C CD2   . HIS E 1 99  ? -45.400  19.658   -17.711 1.00 39.04  ? 99   HIS E CD2   1 
ATOM   13914 C CE1   . HIS E 1 99  ? -45.668  20.593   -19.690 1.00 43.16  ? 99   HIS E CE1   1 
ATOM   13915 N NE2   . HIS E 1 99  ? -45.280  20.815   -18.455 1.00 43.78  ? 99   HIS E NE2   1 
ATOM   13916 N N     . ALA E 1 100 ? -45.079  14.003   -19.401 1.00 38.94  ? 100  ALA E N     1 
ATOM   13917 C CA    . ALA E 1 100 ? -45.185  12.582   -19.091 1.00 32.16  ? 100  ALA E CA    1 
ATOM   13918 C C     . ALA E 1 100 ? -43.793  11.975   -19.161 1.00 34.79  ? 100  ALA E C     1 
ATOM   13919 O O     . ALA E 1 100 ? -42.920  12.534   -19.831 1.00 34.97  ? 100  ALA E O     1 
ATOM   13920 C CB    . ALA E 1 100 ? -46.106  11.933   -20.104 1.00 32.52  ? 100  ALA E CB    1 
ATOM   13921 N N     . PRO E 1 101 ? -43.600  10.785   -18.644 1.00 33.35  ? 101  PRO E N     1 
ATOM   13922 C CA    . PRO E 1 101 ? -42.277  10.201   -18.703 1.00 33.26  ? 101  PRO E CA    1 
ATOM   13923 C C     . PRO E 1 101 ? -41.748  10.036   -20.106 1.00 36.86  ? 101  PRO E C     1 
ATOM   13924 O O     . PRO E 1 101 ? -40.568  10.016   -20.289 1.00 41.34  ? 101  PRO E O     1 
ATOM   13925 C CB    . PRO E 1 101 ? -42.458  8.853    -18.045 1.00 29.59  ? 101  PRO E CB    1 
ATOM   13926 C CG    . PRO E 1 101 ? -43.835  8.794    -17.576 1.00 32.60  ? 101  PRO E CG    1 
ATOM   13927 C CD    . PRO E 1 101 ? -44.409  10.142   -17.626 1.00 33.88  ? 101  PRO E CD    1 
ATOM   13928 N N     . ALA E 1 102 ? -42.601  9.933    -21.090 1.00 38.60  ? 102  ALA E N     1 
ATOM   13929 C CA    . ALA E 1 102 ? -42.129  9.763    -22.427 1.00 34.05  ? 102  ALA E CA    1 
ATOM   13930 C C     . ALA E 1 102 ? -41.236  10.911   -22.896 1.00 40.10  ? 102  ALA E C     1 
ATOM   13931 O O     . ALA E 1 102 ? -40.252  10.670   -23.527 1.00 36.15  ? 102  ALA E O     1 
ATOM   13932 C CB    . ALA E 1 102 ? -43.312  9.596    -23.344 1.00 34.26  ? 102  ALA E CB    1 
ATOM   13933 N N     . ARG E 1 103 ? -41.601  12.147   -22.600 1.00 36.82  ? 103  ARG E N     1 
ATOM   13934 C CA    . ARG E 1 103 ? -40.848  13.338   -22.955 1.00 40.31  ? 103  ARG E CA    1 
ATOM   13935 C C     . ARG E 1 103 ? -40.515  13.447   -24.419 1.00 41.53  ? 103  ARG E C     1 
ATOM   13936 O O     . ARG E 1 103 ? -39.441  13.853   -24.762 1.00 45.94  ? 103  ARG E O     1 
ATOM   13937 C CB    . ARG E 1 103 ? -39.550  13.499   -22.155 1.00 43.90  ? 103  ARG E CB    1 
ATOM   13938 C CG    . ARG E 1 103 ? -39.585  13.142   -20.699 1.00 58.43  ? 103  ARG E CG    1 
ATOM   13939 C CD    . ARG E 1 103 ? -39.768  14.309   -19.762 1.00 76.06  ? 103  ARG E CD    1 
ATOM   13940 N NE    . ARG E 1 103 ? -40.448  13.831   -18.558 1.00 102.49 ? 103  ARG E NE    1 
ATOM   13941 C CZ    . ARG E 1 103 ? -41.092  14.572   -17.658 1.00 90.10  ? 103  ARG E CZ    1 
ATOM   13942 N NH1   . ARG E 1 103 ? -41.675  13.983   -16.631 1.00 69.47  ? 103  ARG E NH1   1 
ATOM   13943 N NH2   . ARG E 1 103 ? -41.150  15.877   -17.779 1.00 78.51  ? 103  ARG E NH2   1 
ATOM   13944 N N     . ARG E 1 104 ? -41.434  13.094   -25.286 1.00 42.70  ? 104  ARG E N     1 
ATOM   13945 C CA    . ARG E 1 104 ? -41.195  13.160   -26.703 1.00 39.35  ? 104  ARG E CA    1 
ATOM   13946 C C     . ARG E 1 104 ? -42.385  13.757   -27.384 1.00 35.50  ? 104  ARG E C     1 
ATOM   13947 O O     . ARG E 1 104 ? -43.468  13.495   -26.996 1.00 35.79  ? 104  ARG E O     1 
ATOM   13948 C CB    . ARG E 1 104 ? -40.997  11.762   -27.258 1.00 36.64  ? 104  ARG E CB    1 
ATOM   13949 C CG    . ARG E 1 104 ? -39.757  11.046   -26.810 1.00 36.03  ? 104  ARG E CG    1 
ATOM   13950 C CD    . ARG E 1 104 ? -40.000  9.565    -26.646 1.00 39.08  ? 104  ARG E CD    1 
ATOM   13951 N NE    . ARG E 1 104 ? -40.499  8.925    -27.839 1.00 39.94  ? 104  ARG E NE    1 
ATOM   13952 C CZ    . ARG E 1 104 ? -40.989  7.699    -27.870 1.00 45.16  ? 104  ARG E CZ    1 
ATOM   13953 N NH1   . ARG E 1 104 ? -41.025  6.986    -26.780 1.00 39.11  ? 104  ARG E NH1   1 
ATOM   13954 N NH2   . ARG E 1 104 ? -41.434  7.185    -28.980 1.00 37.66  ? 104  ARG E NH2   1 
ATOM   13955 N N     . ASP E 1 105 ? -42.181  14.536   -28.422 1.00 32.12  ? 105  ASP E N     1 
ATOM   13956 C CA    . ASP E 1 105 ? -43.314  15.040   -29.139 1.00 35.30  ? 105  ASP E CA    1 
ATOM   13957 C C     . ASP E 1 105 ? -43.627  13.919   -30.118 1.00 40.55  ? 105  ASP E C     1 
ATOM   13958 O O     . ASP E 1 105 ? -42.936  13.730   -31.083 1.00 37.34  ? 105  ASP E O     1 
ATOM   13959 C CB    . ASP E 1 105 ? -42.979  16.327   -29.847 1.00 31.90  ? 105  ASP E CB    1 
ATOM   13960 C CG    . ASP E 1 105 ? -44.164  16.962   -30.453 1.00 39.29  ? 105  ASP E CG    1 
ATOM   13961 O OD1   . ASP E 1 105 ? -45.040  16.236   -30.843 1.00 44.67  ? 105  ASP E OD1   1 
ATOM   13962 O OD2   . ASP E 1 105 ? -44.245  18.173   -30.546 1.00 40.02  ? 105  ASP E OD2   1 
ATOM   13963 N N     . LEU E 1 106 ? -44.698  13.191   -29.824 1.00 35.48  ? 106  LEU E N     1 
ATOM   13964 C CA    . LEU E 1 106 ? -45.097  12.010   -30.581 1.00 33.19  ? 106  LEU E CA    1 
ATOM   13965 C C     . LEU E 1 106 ? -45.647  12.421   -31.946 1.00 33.35  ? 106  LEU E C     1 
ATOM   13966 O O     . LEU E 1 106 ? -45.444  11.711   -32.923 1.00 36.84  ? 106  LEU E O     1 
ATOM   13967 C CB    . LEU E 1 106 ? -46.113  11.216   -29.771 1.00 28.70  ? 106  LEU E CB    1 
ATOM   13968 C CG    . LEU E 1 106 ? -45.598  10.769   -28.406 1.00 32.92  ? 106  LEU E CG    1 
ATOM   13969 C CD1   . LEU E 1 106 ? -46.715  10.219   -27.544 1.00 26.39  ? 106  LEU E CD1   1 
ATOM   13970 C CD2   . LEU E 1 106 ? -44.487  9.734    -28.554 1.00 30.01  ? 106  LEU E CD2   1 
ATOM   13971 N N     . ILE E 1 107 ? -46.299  13.586   -32.015 1.00 27.89  ? 107  ILE E N     1 
ATOM   13972 C CA    . ILE E 1 107 ? -46.757  14.104   -33.292 1.00 31.28  ? 107  ILE E CA    1 
ATOM   13973 C C     . ILE E 1 107 ? -45.572  14.399   -34.220 1.00 35.93  ? 107  ILE E C     1 
ATOM   13974 O O     . ILE E 1 107 ? -45.670  14.163   -35.425 1.00 39.64  ? 107  ILE E O     1 
ATOM   13975 C CB    . ILE E 1 107 ? -47.718  15.289   -33.116 1.00 28.72  ? 107  ILE E CB    1 
ATOM   13976 C CG1   . ILE E 1 107 ? -48.961  14.920   -32.270 1.00 34.48  ? 107  ILE E CG1   1 
ATOM   13977 C CG2   . ILE E 1 107 ? -48.111  15.941   -34.433 1.00 26.77  ? 107  ILE E CG2   1 
ATOM   13978 C CD1   . ILE E 1 107 ? -49.515  13.517   -32.475 1.00 39.94  ? 107  ILE E CD1   1 
ATOM   13979 N N     . ALA E 1 108 ? -44.441  14.876   -33.676 1.00 37.08  ? 108  ALA E N     1 
ATOM   13980 C CA    . ALA E 1 108 ? -43.283  15.157   -34.521 1.00 34.59  ? 108  ALA E CA    1 
ATOM   13981 C C     . ALA E 1 108 ? -42.741  13.835   -35.072 1.00 33.06  ? 108  ALA E C     1 
ATOM   13982 O O     . ALA E 1 108 ? -42.421  13.756   -36.254 1.00 34.81  ? 108  ALA E O     1 
ATOM   13983 C CB    . ALA E 1 108 ? -42.193  15.958   -33.809 1.00 27.16  ? 108  ALA E CB    1 
ATOM   13984 N N     . GLU E 1 109 ? -42.663  12.804   -34.222 1.00 26.69  ? 109  GLU E N     1 
ATOM   13985 C CA    . GLU E 1 109 ? -42.223  11.493   -34.664 1.00 31.92  ? 109  GLU E CA    1 
ATOM   13986 C C     . GLU E 1 109 ? -43.158  10.966   -35.764 1.00 36.67  ? 109  GLU E C     1 
ATOM   13987 O O     . GLU E 1 109 ? -42.684  10.443   -36.777 1.00 41.68  ? 109  GLU E O     1 
ATOM   13988 C CB    . GLU E 1 109 ? -42.140  10.499   -33.514 1.00 28.46  ? 109  GLU E CB    1 
ATOM   13989 C CG    . GLU E 1 109 ? -41.118  10.910   -32.466 1.00 32.71  ? 109  GLU E CG    1 
ATOM   13990 C CD    . GLU E 1 109 ? -41.073  9.952    -31.279 1.00 38.80  ? 109  GLU E CD    1 
ATOM   13991 O OE1   . GLU E 1 109 ? -41.808  8.960    -31.306 1.00 43.11  ? 109  GLU E OE1   1 
ATOM   13992 O OE2   . GLU E 1 109 ? -40.302  10.167   -30.326 1.00 45.58  ? 109  GLU E OE2   1 
ATOM   13993 N N     . PHE E 1 110 ? -44.472  11.183   -35.590 1.00 31.30  ? 110  PHE E N     1 
ATOM   13994 C CA    . PHE E 1 110 ? -45.483  10.668   -36.485 1.00 33.75  ? 110  PHE E CA    1 
ATOM   13995 C C     . PHE E 1 110 ? -45.364  11.326   -37.856 1.00 36.76  ? 110  PHE E C     1 
ATOM   13996 O O     . PHE E 1 110 ? -45.406  10.651   -38.879 1.00 39.84  ? 110  PHE E O     1 
ATOM   13997 C CB    . PHE E 1 110 ? -46.834  10.917   -35.821 1.00 28.33  ? 110  PHE E CB    1 
ATOM   13998 C CG    . PHE E 1 110 ? -48.036  10.764   -36.740 1.00 27.25  ? 110  PHE E CG    1 
ATOM   13999 C CD1   . PHE E 1 110 ? -48.402  9.514    -37.240 1.00 27.91  ? 110  PHE E CD1   1 
ATOM   14000 C CD2   . PHE E 1 110 ? -48.824  11.860   -37.072 1.00 24.74  ? 110  PHE E CD2   1 
ATOM   14001 C CE1   . PHE E 1 110 ? -49.517  9.375    -38.067 1.00 26.89  ? 110  PHE E CE1   1 
ATOM   14002 C CE2   . PHE E 1 110 ? -49.946  11.713   -37.892 1.00 25.76  ? 110  PHE E CE2   1 
ATOM   14003 C CZ    . PHE E 1 110 ? -50.286  10.465   -38.388 1.00 25.52  ? 110  PHE E CZ    1 
ATOM   14004 N N     . VAL E 1 111 ? -45.221  12.648   -37.870 1.00 36.24  ? 111  VAL E N     1 
ATOM   14005 C CA    . VAL E 1 111 ? -45.163  13.394   -39.120 1.00 35.17  ? 111  VAL E CA    1 
ATOM   14006 C C     . VAL E 1 111 ? -43.926  12.990   -39.926 1.00 35.26  ? 111  VAL E C     1 
ATOM   14007 O O     . VAL E 1 111 ? -44.007  12.818   -41.144 1.00 38.15  ? 111  VAL E O     1 
ATOM   14008 C CB    . VAL E 1 111 ? -45.197  14.897   -38.769 1.00 31.89  ? 111  VAL E CB    1 
ATOM   14009 C CG1   . VAL E 1 111 ? -44.509  15.756   -39.787 1.00 32.50  ? 111  VAL E CG1   1 
ATOM   14010 C CG2   . VAL E 1 111 ? -46.619  15.383   -38.508 1.00 31.22  ? 111  VAL E CG2   1 
ATOM   14011 N N     . ALA E 1 112 ? -42.774  12.822   -39.248 1.00 32.82  ? 112  ALA E N     1 
ATOM   14012 C CA    . ALA E 1 112 ? -41.538  12.456   -39.933 1.00 32.79  ? 112  ALA E CA    1 
ATOM   14013 C C     . ALA E 1 112 ? -41.696  11.049   -40.537 1.00 36.48  ? 112  ALA E C     1 
ATOM   14014 O O     . ALA E 1 112 ? -41.355  10.824   -41.707 1.00 37.28  ? 112  ALA E O     1 
ATOM   14015 C CB    . ALA E 1 112 ? -40.346  12.563   -38.996 1.00 23.41  ? 112  ALA E CB    1 
ATOM   14016 N N     . ALA E 1 113 ? -42.285  10.126   -39.757 1.00 31.87  ? 113  ALA E N     1 
ATOM   14017 C CA    . ALA E 1 113 ? -42.470  8.762    -40.213 1.00 31.41  ? 113  ALA E CA    1 
ATOM   14018 C C     . ALA E 1 113 ? -43.396  8.725    -41.429 1.00 31.31  ? 113  ALA E C     1 
ATOM   14019 O O     . ALA E 1 113 ? -43.087  8.021    -42.398 1.00 31.22  ? 113  ALA E O     1 
ATOM   14020 C CB    . ALA E 1 113 ? -42.953  7.880    -39.091 1.00 29.01  ? 113  ALA E CB    1 
ATOM   14021 N N     . CYS E 1 114 ? -44.476  9.524    -41.410 1.00 28.22  ? 114  CYS E N     1 
ATOM   14022 C CA    . CYS E 1 114 ? -45.388  9.557    -42.536 1.00 32.89  ? 114  CYS E CA    1 
ATOM   14023 C C     . CYS E 1 114 ? -44.676  10.039   -43.796 1.00 39.57  ? 114  CYS E C     1 
ATOM   14024 O O     . CYS E 1 114 ? -44.865  9.471    -44.872 1.00 36.53  ? 114  CYS E O     1 
ATOM   14025 C CB    . CYS E 1 114 ? -46.604  10.440   -42.308 1.00 32.33  ? 114  CYS E CB    1 
ATOM   14026 S SG    . CYS E 1 114 ? -47.785  9.761    -41.111 1.00 35.96  ? 114  CYS E SG    1 
ATOM   14027 N N     . ARG E 1 115 ? -43.867  11.094   -43.656 1.00 42.02  ? 115  ARG E N     1 
ATOM   14028 C CA    . ARG E 1 115 ? -43.243  11.692   -44.829 1.00 44.53  ? 115  ARG E CA    1 
ATOM   14029 C C     . ARG E 1 115 ? -42.260  10.712   -45.457 1.00 38.61  ? 115  ARG E C     1 
ATOM   14030 O O     . ARG E 1 115 ? -42.178  10.645   -46.664 1.00 37.45  ? 115  ARG E O     1 
ATOM   14031 C CB    . ARG E 1 115 ? -42.514  13.008   -44.557 1.00 47.65  ? 115  ARG E CB    1 
ATOM   14032 C CG    . ARG E 1 115 ? -43.591  14.080   -44.545 1.00 51.45  ? 115  ARG E CG    1 
ATOM   14033 C CD    . ARG E 1 115 ? -43.023  15.277   -43.847 1.00 58.10  ? 115  ARG E CD    1 
ATOM   14034 N NE    . ARG E 1 115 ? -44.147  16.163   -43.541 1.00 62.83  ? 115  ARG E NE    1 
ATOM   14035 C CZ    . ARG E 1 115 ? -44.012  17.197   -42.723 1.00 66.23  ? 115  ARG E CZ    1 
ATOM   14036 N NH1   . ARG E 1 115 ? -42.896  17.327   -42.018 1.00 55.35  ? 115  ARG E NH1   1 
ATOM   14037 N NH2   . ARG E 1 115 ? -45.015  18.042   -42.568 1.00 64.30  ? 115  ARG E NH2   1 
ATOM   14038 N N     . GLU E 1 116 ? -41.534  9.952    -44.642 1.00 37.78  ? 116  GLU E N     1 
ATOM   14039 C CA    . GLU E 1 116 ? -40.575  9.025    -45.206 1.00 43.35  ? 116  GLU E CA    1 
ATOM   14040 C C     . GLU E 1 116 ? -41.280  7.910    -45.981 1.00 42.53  ? 116  GLU E C     1 
ATOM   14041 O O     . GLU E 1 116 ? -40.650  7.315    -46.835 1.00 43.64  ? 116  GLU E O     1 
ATOM   14042 C CB    . GLU E 1 116 ? -39.402  8.662    -44.293 1.00 48.70  ? 116  GLU E CB    1 
ATOM   14043 C CG    . GLU E 1 116 ? -39.716  7.682    -43.175 1.00 76.51  ? 116  GLU E CG    1 
ATOM   14044 C CD    . GLU E 1 116 ? -38.675  7.830    -42.072 1.00 98.46  ? 116  GLU E CD    1 
ATOM   14045 O OE1   . GLU E 1 116 ? -37.901  8.809    -42.161 1.00 99.31  ? 116  GLU E OE1   1 
ATOM   14046 O OE2   . GLU E 1 116 ? -38.648  7.014    -41.128 1.00 106.99 ? 116  GLU E OE2   1 
ATOM   14047 N N     . GLU E 1 117 ? -42.566  7.642    -45.711 1.00 40.07  ? 117  GLU E N     1 
ATOM   14048 C CA    . GLU E 1 117 ? -43.281  6.561    -46.376 1.00 38.16  ? 117  GLU E CA    1 
ATOM   14049 C C     . GLU E 1 117 ? -44.244  7.119    -47.420 1.00 41.27  ? 117  GLU E C     1 
ATOM   14050 O O     . GLU E 1 117 ? -45.063  6.380    -47.962 1.00 41.66  ? 117  GLU E O     1 
ATOM   14051 C CB    . GLU E 1 117 ? -44.058  5.694    -45.381 1.00 42.71  ? 117  GLU E CB    1 
ATOM   14052 C CG    . GLU E 1 117 ? -43.134  4.844    -44.497 1.00 44.33  ? 117  GLU E CG    1 
ATOM   14053 C CD    . GLU E 1 117 ? -42.585  3.558    -45.116 1.00 55.02  ? 117  GLU E CD    1 
ATOM   14054 O OE1   . GLU E 1 117 ? -42.659  3.350    -46.348 1.00 59.46  ? 117  GLU E OE1   1 
ATOM   14055 O OE2   . GLU E 1 117 ? -42.118  2.703    -44.331 1.00 63.06  ? 117  GLU E OE2   1 
ATOM   14056 N N     . ASP E 1 118 ? -44.167  8.431    -47.679 1.00 37.93  ? 118  ASP E N     1 
ATOM   14057 C CA    . ASP E 1 118 ? -45.058  9.097    -48.614 1.00 38.05  ? 118  ASP E CA    1 
ATOM   14058 C C     . ASP E 1 118 ? -46.527  8.990    -48.182 1.00 37.68  ? 118  ASP E C     1 
ATOM   14059 O O     . ASP E 1 118 ? -47.433  8.883    -49.016 1.00 37.58  ? 118  ASP E O     1 
ATOM   14060 C CB    . ASP E 1 118 ? -44.675  8.714    -50.039 1.00 51.09  ? 118  ASP E CB    1 
ATOM   14061 C CG    . ASP E 1 118 ? -45.289  9.547    -51.154 1.00 72.39  ? 118  ASP E CG    1 
ATOM   14062 O OD1   . ASP E 1 118 ? -45.290  10.792   -51.018 1.00 78.30  ? 118  ASP E OD1   1 
ATOM   14063 O OD2   . ASP E 1 118 ? -45.755  8.949    -52.157 1.00 82.27  ? 118  ASP E OD2   1 
ATOM   14064 N N     . LEU E 1 119 ? -46.803  9.059    -46.878 1.00 36.37  ? 119  LEU E N     1 
ATOM   14065 C CA    . LEU E 1 119 ? -48.187  9.075    -46.400 1.00 37.57  ? 119  LEU E CA    1 
ATOM   14066 C C     . LEU E 1 119 ? -48.543  10.482   -45.939 1.00 36.66  ? 119  LEU E C     1 
ATOM   14067 O O     . LEU E 1 119 ? -47.694  11.163   -45.371 1.00 40.84  ? 119  LEU E O     1 
ATOM   14068 C CB    . LEU E 1 119 ? -48.271  8.117    -45.209 1.00 38.11  ? 119  LEU E CB    1 
ATOM   14069 C CG    . LEU E 1 119 ? -47.854  6.669    -45.474 1.00 34.52  ? 119  LEU E CG    1 
ATOM   14070 C CD1   . LEU E 1 119 ? -47.879  5.863    -44.186 1.00 35.51  ? 119  LEU E CD1   1 
ATOM   14071 C CD2   . LEU E 1 119 ? -48.784  6.068    -46.520 1.00 30.94  ? 119  LEU E CD2   1 
ATOM   14072 N N     . LEU E 1 120 ? -49.798  10.896   -46.119 1.00 34.74  ? 120  LEU E N     1 
ATOM   14073 C CA    . LEU E 1 120 ? -50.233  12.156   -45.530 1.00 38.51  ? 120  LEU E CA    1 
ATOM   14074 C C     . LEU E 1 120 ? -50.547  12.001   -44.037 1.00 38.07  ? 120  LEU E C     1 
ATOM   14075 O O     . LEU E 1 120 ? -51.333  11.133   -43.661 1.00 36.23  ? 120  LEU E O     1 
ATOM   14076 C CB    . LEU E 1 120 ? -51.415  12.743   -46.299 1.00 34.33  ? 120  LEU E CB    1 
ATOM   14077 C CG    . LEU E 1 120 ? -51.114  13.162   -47.738 1.00 34.58  ? 120  LEU E CG    1 
ATOM   14078 C CD1   . LEU E 1 120 ? -52.341  13.819   -48.301 1.00 33.50  ? 120  LEU E CD1   1 
ATOM   14079 C CD2   . LEU E 1 120 ? -49.909  14.111   -47.830 1.00 32.97  ? 120  LEU E CD2   1 
ATOM   14080 N N     . PRO E 1 121 ? -49.958  12.837   -43.136 1.00 37.36  ? 121  PRO E N     1 
ATOM   14081 C CA    . PRO E 1 121 ? -50.337  12.843   -41.721 1.00 31.65  ? 121  PRO E CA    1 
ATOM   14082 C C     . PRO E 1 121 ? -51.580  13.682   -41.451 1.00 30.44  ? 121  PRO E C     1 
ATOM   14083 O O     . PRO E 1 121 ? -51.666  14.829   -41.892 1.00 32.48  ? 121  PRO E O     1 
ATOM   14084 C CB    . PRO E 1 121 ? -49.100  13.402   -41.024 1.00 29.34  ? 121  PRO E CB    1 
ATOM   14085 C CG    . PRO E 1 121 ? -48.618  14.402   -42.070 1.00 32.89  ? 121  PRO E CG    1 
ATOM   14086 C CD    . PRO E 1 121 ? -48.895  13.811   -43.438 1.00 34.39  ? 121  PRO E CD    1 
ATOM   14087 N N     . PHE E 1 122 ? -52.561  13.090   -40.764 1.00 29.75  ? 122  PHE E N     1 
ATOM   14088 C CA    . PHE E 1 122 ? -53.773  13.813   -40.420 1.00 30.70  ? 122  PHE E CA    1 
ATOM   14089 C C     . PHE E 1 122 ? -53.900  13.835   -38.905 1.00 30.54  ? 122  PHE E C     1 
ATOM   14090 O O     . PHE E 1 122 ? -53.543  12.847   -38.241 1.00 28.23  ? 122  PHE E O     1 
ATOM   14091 C CB    . PHE E 1 122 ? -55.042  13.153   -40.958 1.00 30.16  ? 122  PHE E CB    1 
ATOM   14092 C CG    . PHE E 1 122 ? -55.421  13.464   -42.395 1.00 27.37  ? 122  PHE E CG    1 
ATOM   14093 C CD1   . PHE E 1 122 ? -54.522  13.269   -43.429 1.00 26.28  ? 122  PHE E CD1   1 
ATOM   14094 C CD2   . PHE E 1 122 ? -56.695  13.940   -42.700 1.00 29.41  ? 122  PHE E CD2   1 
ATOM   14095 C CE1   . PHE E 1 122 ? -54.899  13.550   -44.747 1.00 28.20  ? 122  PHE E CE1   1 
ATOM   14096 C CE2   . PHE E 1 122 ? -57.064  14.211   -44.009 1.00 29.81  ? 122  PHE E CE2   1 
ATOM   14097 C CZ    . PHE E 1 122 ? -56.165  14.024   -45.030 1.00 28.08  ? 122  PHE E CZ    1 
ATOM   14098 N N     . PHE E 1 123 ? -54.428  14.954   -38.381 1.00 29.43  ? 123  PHE E N     1 
ATOM   14099 C CA    . PHE E 1 123 ? -54.507  15.119   -36.940 1.00 27.71  ? 123  PHE E CA    1 
ATOM   14100 C C     . PHE E 1 123 ? -55.961  15.102   -36.498 1.00 29.85  ? 123  PHE E C     1 
ATOM   14101 O O     . PHE E 1 123 ? -56.737  15.990   -36.873 1.00 31.98  ? 123  PHE E O     1 
ATOM   14102 C CB    . PHE E 1 123 ? -53.913  16.476   -36.564 1.00 26.28  ? 123  PHE E CB    1 
ATOM   14103 C CG    . PHE E 1 123 ? -52.437  16.655   -36.877 1.00 28.35  ? 123  PHE E CG    1 
ATOM   14104 C CD1   . PHE E 1 123 ? -51.558  15.567   -36.881 1.00 25.63  ? 123  PHE E CD1   1 
ATOM   14105 C CD2   . PHE E 1 123 ? -51.923  17.934   -37.112 1.00 27.83  ? 123  PHE E CD2   1 
ATOM   14106 C CE1   . PHE E 1 123 ? -50.199  15.749   -37.152 1.00 28.24  ? 123  PHE E CE1   1 
ATOM   14107 C CE2   . PHE E 1 123 ? -50.559  18.118   -37.365 1.00 29.09  ? 123  PHE E CE2   1 
ATOM   14108 C CZ    . PHE E 1 123 ? -49.697  17.025   -37.393 1.00 29.87  ? 123  PHE E CZ    1 
ATOM   14109 N N     . TYR E 1 124 ? -56.329  14.090   -35.705 1.00 25.84  ? 124  TYR E N     1 
ATOM   14110 C CA    . TYR E 1 124 ? -57.652  14.090   -35.105 1.00 25.14  ? 124  TYR E CA    1 
ATOM   14111 C C     . TYR E 1 124 ? -57.573  15.000   -33.878 1.00 26.49  ? 124  TYR E C     1 
ATOM   14112 O O     . TYR E 1 124 ? -56.600  14.941   -33.103 1.00 25.10  ? 124  TYR E O     1 
ATOM   14113 C CB    . TYR E 1 124 ? -58.000  12.649   -34.694 1.00 25.49  ? 124  TYR E CB    1 
ATOM   14114 C CG    . TYR E 1 124 ? -59.179  12.522   -33.728 1.00 28.92  ? 124  TYR E CG    1 
ATOM   14115 C CD1   . TYR E 1 124 ? -59.051  12.910   -32.390 1.00 27.18  ? 124  TYR E CD1   1 
ATOM   14116 C CD2   . TYR E 1 124 ? -60.420  12.027   -34.148 1.00 26.74  ? 124  TYR E CD2   1 
ATOM   14117 C CE1   . TYR E 1 124 ? -60.127  12.823   -31.515 1.00 29.73  ? 124  TYR E CE1   1 
ATOM   14118 C CE2   . TYR E 1 124 ? -61.497  11.931   -33.279 1.00 26.06  ? 124  TYR E CE2   1 
ATOM   14119 C CZ    . TYR E 1 124 ? -61.350  12.336   -31.962 1.00 31.99  ? 124  TYR E CZ    1 
ATOM   14120 O OH    . TYR E 1 124 ? -62.386  12.255   -31.072 1.00 29.81  ? 124  TYR E OH    1 
ATOM   14121 N N     . MET E 1 125 ? -58.616  15.814   -33.689 1.00 27.33  ? 125  MET E N     1 
ATOM   14122 C CA    . MET E 1 125 ? -58.684  16.697   -32.529 1.00 27.60  ? 125  MET E CA    1 
ATOM   14123 C C     . MET E 1 125 ? -60.115  16.671   -31.997 1.00 24.89  ? 125  MET E C     1 
ATOM   14124 O O     . MET E 1 125 ? -61.063  16.949   -32.743 1.00 26.74  ? 125  MET E O     1 
ATOM   14125 C CB    . MET E 1 125 ? -58.251  18.129   -32.909 1.00 27.09  ? 125  MET E CB    1 
ATOM   14126 C CG    . MET E 1 125 ? -58.637  19.196   -31.872 1.00 28.56  ? 125  MET E CG    1 
ATOM   14127 S SD    . MET E 1 125 ? -57.719  19.062   -30.323 1.00 35.90  ? 125  MET E SD    1 
ATOM   14128 C CE    . MET E 1 125 ? -56.028  19.392   -30.861 1.00 26.76  ? 125  MET E CE    1 
ATOM   14129 N N     . ALA E 1 126 ? -60.274  16.307   -30.721 1.00 25.86  ? 126  ALA E N     1 
ATOM   14130 C CA    . ALA E 1 126 ? -61.604  16.329   -30.106 1.00 27.96  ? 126  ALA E CA    1 
ATOM   14131 C C     . ALA E 1 126 ? -61.972  17.757   -29.701 1.00 31.58  ? 126  ALA E C     1 
ATOM   14132 O O     . ALA E 1 126 ? -61.197  18.451   -29.049 1.00 34.22  ? 126  ALA E O     1 
ATOM   14133 C CB    . ALA E 1 126 ? -61.651  15.418   -28.901 1.00 23.23  ? 126  ALA E CB    1 
ATOM   14134 N N     . THR E 1 127 ? -63.172  18.201   -30.077 1.00 33.51  ? 127  THR E N     1 
ATOM   14135 C CA    . THR E 1 127 ? -63.584  19.543   -29.708 1.00 30.13  ? 127  THR E CA    1 
ATOM   14136 C C     . THR E 1 127 ? -64.402  19.511   -28.424 1.00 33.44  ? 127  THR E C     1 
ATOM   14137 O O     . THR E 1 127 ? -64.549  20.536   -27.771 1.00 43.30  ? 127  THR E O     1 
ATOM   14138 C CB    . THR E 1 127 ? -64.310  20.204   -30.873 1.00 30.81  ? 127  THR E CB    1 
ATOM   14139 O OG1   . THR E 1 127 ? -65.503  19.448   -31.009 1.00 30.82  ? 127  THR E OG1   1 
ATOM   14140 C CG2   . THR E 1 127 ? -63.509  20.201   -32.161 1.00 28.09  ? 127  THR E CG2   1 
ATOM   14141 N N     . TYR E 1 128 ? -64.933  18.339   -28.063 1.00 31.54  ? 128  TYR E N     1 
ATOM   14142 C CA    . TYR E 1 128 ? -65.569  18.164   -26.771 1.00 30.10  ? 128  TYR E CA    1 
ATOM   14143 C C     . TYR E 1 128 ? -64.508  17.662   -25.788 1.00 37.12  ? 128  TYR E C     1 
ATOM   14144 O O     . TYR E 1 128 ? -63.946  16.579   -25.990 1.00 35.92  ? 128  TYR E O     1 
ATOM   14145 C CB    . TYR E 1 128 ? -66.666  17.126   -27.019 1.00 29.00  ? 128  TYR E CB    1 
ATOM   14146 C CG    . TYR E 1 128 ? -67.427  16.585   -25.817 1.00 30.77  ? 128  TYR E CG    1 
ATOM   14147 C CD1   . TYR E 1 128 ? -67.630  17.349   -24.668 1.00 26.99  ? 128  TYR E CD1   1 
ATOM   14148 C CD2   . TYR E 1 128 ? -67.963  15.292   -25.841 1.00 30.73  ? 128  TYR E CD2   1 
ATOM   14149 C CE1   . TYR E 1 128 ? -68.348  16.856   -23.589 1.00 30.80  ? 128  TYR E CE1   1 
ATOM   14150 C CE2   . TYR E 1 128 ? -68.685  14.791   -24.767 1.00 30.33  ? 128  TYR E CE2   1 
ATOM   14151 C CZ    . TYR E 1 128 ? -68.880  15.575   -23.640 1.00 33.96  ? 128  TYR E CZ    1 
ATOM   14152 O OH    . TYR E 1 128 ? -69.579  15.088   -22.577 1.00 33.86  ? 128  TYR E OH    1 
ATOM   14153 N N     . ASP E 1 129 ? -64.239  18.449   -24.731 1.00 36.38  ? 129  ASP E N     1 
ATOM   14154 C CA    . ASP E 1 129 ? -63.051  18.249   -23.905 1.00 34.27  ? 129  ASP E CA    1 
ATOM   14155 C C     . ASP E 1 129 ? -63.461  18.062   -22.444 1.00 32.85  ? 129  ASP E C     1 
ATOM   14156 O O     . ASP E 1 129 ? -64.202  18.887   -21.927 1.00 35.34  ? 129  ASP E O     1 
ATOM   14157 C CB    . ASP E 1 129 ? -62.091  19.406   -24.116 1.00 29.48  ? 129  ASP E CB    1 
ATOM   14158 C CG    . ASP E 1 129 ? -60.734  19.308   -23.440 1.00 35.94  ? 129  ASP E CG    1 
ATOM   14159 O OD1   . ASP E 1 129 ? -60.705  19.002   -22.209 1.00 40.01  ? 129  ASP E OD1   1 
ATOM   14160 O OD2   . ASP E 1 129 ? -59.712  19.553   -24.150 1.00 32.96  ? 129  ASP E OD2   1 
ATOM   14161 N N     . TRP E 1 130 ? -63.001  16.982   -21.793 1.00 28.09  ? 130  TRP E N     1 
ATOM   14162 C CA    . TRP E 1 130 ? -63.381  16.666   -20.421 1.00 31.33  ? 130  TRP E CA    1 
ATOM   14163 C C     . TRP E 1 130 ? -62.325  17.165   -19.444 1.00 32.29  ? 130  TRP E C     1 
ATOM   14164 O O     . TRP E 1 130 ? -62.503  17.014   -18.237 1.00 32.94  ? 130  TRP E O     1 
ATOM   14165 C CB    . TRP E 1 130 ? -63.554  15.154   -20.190 1.00 32.08  ? 130  TRP E CB    1 
ATOM   14166 C CG    . TRP E 1 130 ? -64.545  14.476   -21.103 1.00 41.27  ? 130  TRP E CG    1 
ATOM   14167 C CD1   . TRP E 1 130 ? -65.623  15.059   -21.700 1.00 39.14  ? 130  TRP E CD1   1 
ATOM   14168 C CD2   . TRP E 1 130 ? -64.533  13.096   -21.543 1.00 36.36  ? 130  TRP E CD2   1 
ATOM   14169 N NE1   . TRP E 1 130 ? -66.269  14.150   -22.490 1.00 40.99  ? 130  TRP E NE1   1 
ATOM   14170 C CE2   . TRP E 1 130 ? -65.642  12.931   -22.408 1.00 39.31  ? 130  TRP E CE2   1 
ATOM   14171 C CE3   . TRP E 1 130 ? -63.703  11.994   -21.297 1.00 33.97  ? 130  TRP E CE3   1 
ATOM   14172 C CZ2   . TRP E 1 130 ? -65.948  11.710   -23.026 1.00 33.80  ? 130  TRP E CZ2   1 
ATOM   14173 C CZ3   . TRP E 1 130 ? -64.001  10.786   -21.890 1.00 33.52  ? 130  TRP E CZ3   1 
ATOM   14174 C CH2   . TRP E 1 130 ? -65.101  10.655   -22.754 1.00 35.07  ? 130  TRP E CH2   1 
ATOM   14175 N N     . HIS E 1 131 ? -61.192  17.664   -19.946 1.00 32.22  ? 131  HIS E N     1 
ATOM   14176 C CA    . HIS E 1 131 ? -60.096  18.019   -19.051 1.00 36.54  ? 131  HIS E CA    1 
ATOM   14177 C C     . HIS E 1 131 ? -60.220  19.458   -18.538 1.00 36.57  ? 131  HIS E C     1 
ATOM   14178 O O     . HIS E 1 131 ? -60.156  19.673   -17.343 1.00 34.55  ? 131  HIS E O     1 
ATOM   14179 C CB    . HIS E 1 131 ? -58.742  17.873   -19.735 1.00 32.00  ? 131  HIS E CB    1 
ATOM   14180 C CG    . HIS E 1 131 ? -57.631  18.393   -18.897 1.00 36.78  ? 131  HIS E CG    1 
ATOM   14181 N ND1   . HIS E 1 131 ? -57.277  17.813   -17.689 1.00 32.99  ? 131  HIS E ND1   1 
ATOM   14182 C CD2   . HIS E 1 131 ? -56.761  19.424   -19.106 1.00 32.94  ? 131  HIS E CD2   1 
ATOM   14183 C CE1   . HIS E 1 131 ? -56.226  18.459   -17.182 1.00 29.10  ? 131  HIS E CE1   1 
ATOM   14184 N NE2   . HIS E 1 131 ? -55.881  19.438   -18.035 1.00 30.90  ? 131  HIS E NE2   1 
ATOM   14185 N N     . THR E 1 132 ? -60.344  20.435   -19.435 1.00 31.98  ? 132  THR E N     1 
ATOM   14186 C CA    . THR E 1 132 ? -60.331  21.837   -19.024 1.00 37.11  ? 132  THR E CA    1 
ATOM   14187 C C     . THR E 1 132 ? -61.712  22.256   -18.507 1.00 39.16  ? 132  THR E C     1 
ATOM   14188 O O     . THR E 1 132 ? -62.713  22.116   -19.199 1.00 41.73  ? 132  THR E O     1 
ATOM   14189 C CB    . THR E 1 132 ? -59.860  22.735   -20.168 1.00 34.26  ? 132  THR E CB    1 
ATOM   14190 O OG1   . THR E 1 132 ? -60.112  24.039   -19.656 1.00 31.72  ? 132  THR E OG1   1 
ATOM   14191 C CG2   . THR E 1 132 ? -60.627  22.484   -21.468 1.00 33.42  ? 132  THR E CG2   1 
ATOM   14192 N N     . PRO E 1 133 ? -61.801  22.834   -17.290 1.00 40.30  ? 133  PRO E N     1 
ATOM   14193 C CA    . PRO E 1 133 ? -63.067  23.393   -16.804 1.00 35.34  ? 133  PRO E CA    1 
ATOM   14194 C C     . PRO E 1 133 ? -63.596  24.538   -17.674 1.00 32.39  ? 133  PRO E C     1 
ATOM   14195 O O     . PRO E 1 133 ? -64.775  24.865   -17.618 1.00 32.94  ? 133  PRO E O     1 
ATOM   14196 C CB    . PRO E 1 133 ? -62.794  23.791   -15.356 1.00 36.39  ? 133  PRO E CB    1 
ATOM   14197 C CG    . PRO E 1 133 ? -61.296  23.772   -15.217 1.00 36.88  ? 133  PRO E CG    1 
ATOM   14198 C CD    . PRO E 1 133 ? -60.675  22.994   -16.347 1.00 38.95  ? 133  PRO E CD    1 
ATOM   14199 N N     . LEU E 1 134 ? -62.748  25.106   -18.543 1.00 29.28  ? 134  LEU E N     1 
ATOM   14200 C CA    . LEU E 1 134 ? -63.226  26.115   -19.481 1.00 31.34  ? 134  LEU E CA    1 
ATOM   14201 C C     . LEU E 1 134 ? -64.451  25.619   -20.263 1.00 36.07  ? 134  LEU E C     1 
ATOM   14202 O O     . LEU E 1 134 ? -65.349  26.397   -20.583 1.00 34.78  ? 134  LEU E O     1 
ATOM   14203 C CB    . LEU E 1 134 ? -62.151  26.633   -20.437 1.00 31.38  ? 134  LEU E CB    1 
ATOM   14204 C CG    . LEU E 1 134 ? -60.916  27.263   -19.785 1.00 30.49  ? 134  LEU E CG    1 
ATOM   14205 C CD1   . LEU E 1 134 ? -59.902  27.643   -20.891 1.00 30.44  ? 134  LEU E CD1   1 
ATOM   14206 C CD2   . LEU E 1 134 ? -61.239  28.459   -18.893 1.00 27.12  ? 134  LEU E CD2   1 
ATOM   14207 N N     . TYR E 1 135 ? -64.503  24.338   -20.575 1.00 41.43  ? 135  TYR E N     1 
ATOM   14208 C CA    . TYR E 1 135 ? -65.542  23.847   -21.453 1.00 39.29  ? 135  TYR E CA    1 
ATOM   14209 C C     . TYR E 1 135 ? -66.953  24.089   -20.984 1.00 39.01  ? 135  TYR E C     1 
ATOM   14210 O O     . TYR E 1 135 ? -67.762  24.536   -21.745 1.00 33.58  ? 135  TYR E O     1 
ATOM   14211 C CB    . TYR E 1 135 ? -65.319  22.372   -21.766 1.00 34.39  ? 135  TYR E CB    1 
ATOM   14212 C CG    . TYR E 1 135 ? -66.185  21.836   -22.854 1.00 31.17  ? 135  TYR E CG    1 
ATOM   14213 C CD1   . TYR E 1 135 ? -65.850  22.009   -24.159 1.00 31.18  ? 135  TYR E CD1   1 
ATOM   14214 C CD2   . TYR E 1 135 ? -67.328  21.162   -22.578 1.00 31.47  ? 135  TYR E CD2   1 
ATOM   14215 C CE1   . TYR E 1 135 ? -66.629  21.534   -25.158 1.00 30.30  ? 135  TYR E CE1   1 
ATOM   14216 C CE2   . TYR E 1 135 ? -68.121  20.701   -23.577 1.00 32.48  ? 135  TYR E CE2   1 
ATOM   14217 C CZ    . TYR E 1 135 ? -67.752  20.883   -24.860 1.00 33.38  ? 135  TYR E CZ    1 
ATOM   14218 O OH    . TYR E 1 135 ? -68.535  20.409   -25.828 1.00 38.74  ? 135  TYR E OH    1 
ATOM   14219 N N     . ASP E 1 136 ? -67.232  23.834   -19.729 1.00 41.40  ? 136  ASP E N     1 
ATOM   14220 C CA    . ASP E 1 136 ? -68.541  24.104   -19.211 1.00 50.19  ? 136  ASP E CA    1 
ATOM   14221 C C     . ASP E 1 136 ? -68.693  25.495   -18.585 1.00 55.32  ? 136  ASP E C     1 
ATOM   14222 O O     . ASP E 1 136 ? -69.711  26.119   -18.734 1.00 49.26  ? 136  ASP E O     1 
ATOM   14223 C CB    . ASP E 1 136 ? -68.974  23.007   -18.258 1.00 48.55  ? 136  ASP E CB    1 
ATOM   14224 C CG    . ASP E 1 136 ? -69.351  21.742   -18.967 1.00 56.91  ? 136  ASP E CG    1 
ATOM   14225 O OD1   . ASP E 1 136 ? -69.932  21.789   -20.054 1.00 49.83  ? 136  ASP E OD1   1 
ATOM   14226 O OD2   . ASP E 1 136 ? -69.077  20.680   -18.426 1.00 59.27  ? 136  ASP E OD2   1 
ATOM   14227 N N     . ASP E 1 137 ? -67.675  25.934   -17.859 1.00 54.69  ? 137  ASP E N     1 
ATOM   14228 C CA    . ASP E 1 137 ? -67.603  27.222   -17.175 1.00 49.36  ? 137  ASP E CA    1 
ATOM   14229 C C     . ASP E 1 137 ? -67.483  28.505   -18.010 1.00 46.68  ? 137  ASP E C     1 
ATOM   14230 O O     . ASP E 1 137 ? -68.018  29.505   -17.654 1.00 51.47  ? 137  ASP E O     1 
ATOM   14231 C CB    . ASP E 1 137 ? -66.554  27.153   -16.074 1.00 58.02  ? 137  ASP E CB    1 
ATOM   14232 C CG    . ASP E 1 137 ? -66.760  28.188   -14.988 1.00 78.12  ? 137  ASP E CG    1 
ATOM   14233 O OD1   . ASP E 1 137 ? -67.614  27.989   -14.103 1.00 74.10  ? 137  ASP E OD1   1 
ATOM   14234 O OD2   . ASP E 1 137 ? -66.041  29.206   -14.995 1.00 89.22  ? 137  ASP E OD2   1 
ATOM   14235 N N     . ASP E 1 138 ? -66.721  28.485   -19.080 1.00 45.67  ? 138  ASP E N     1 
ATOM   14236 C CA    . ASP E 1 138 ? -66.547  29.646   -19.937 1.00 42.23  ? 138  ASP E CA    1 
ATOM   14237 C C     . ASP E 1 138 ? -66.297  29.194   -21.360 1.00 40.38  ? 138  ASP E C     1 
ATOM   14238 O O     . ASP E 1 138 ? -65.188  29.213   -21.809 1.00 39.01  ? 138  ASP E O     1 
ATOM   14239 C CB    . ASP E 1 138 ? -65.354  30.452   -19.433 1.00 41.92  ? 138  ASP E CB    1 
ATOM   14240 C CG    . ASP E 1 138 ? -65.296  31.846   -19.961 1.00 45.18  ? 138  ASP E CG    1 
ATOM   14241 O OD1   . ASP E 1 138 ? -66.053  32.254   -20.836 1.00 48.40  ? 138  ASP E OD1   1 
ATOM   14242 O OD2   . ASP E 1 138 ? -64.443  32.569   -19.490 1.00 53.74  ? 138  ASP E OD2   1 
ATOM   14243 N N     . PHE E 1 139 ? -67.342  28.878   -22.093 1.00 38.70  ? 139  PHE E N     1 
ATOM   14244 C CA    . PHE E 1 139 ? -67.208  28.342   -23.428 1.00 35.27  ? 139  PHE E CA    1 
ATOM   14245 C C     . PHE E 1 139 ? -66.478  29.230   -24.417 1.00 39.67  ? 139  PHE E C     1 
ATOM   14246 O O     . PHE E 1 139 ? -65.715  28.733   -25.183 1.00 39.88  ? 139  PHE E O     1 
ATOM   14247 C CB    . PHE E 1 139 ? -68.574  27.905   -23.952 1.00 39.47  ? 139  PHE E CB    1 
ATOM   14248 C CG    . PHE E 1 139 ? -68.521  27.078   -25.191 1.00 41.08  ? 139  PHE E CG    1 
ATOM   14249 C CD1   . PHE E 1 139 ? -68.069  25.796   -25.155 1.00 35.65  ? 139  PHE E CD1   1 
ATOM   14250 C CD2   . PHE E 1 139 ? -68.944  27.590   -26.382 1.00 40.01  ? 139  PHE E CD2   1 
ATOM   14251 C CE1   . PHE E 1 139 ? -68.013  25.045   -26.285 1.00 35.72  ? 139  PHE E CE1   1 
ATOM   14252 C CE2   . PHE E 1 139 ? -68.898  26.841   -27.516 1.00 44.95  ? 139  PHE E CE2   1 
ATOM   14253 C CZ    . PHE E 1 139 ? -68.431  25.564   -27.465 1.00 39.09  ? 139  PHE E CZ    1 
ATOM   14254 N N     . PRO E 1 140 ? -66.721  30.541   -24.418 1.00 43.67  ? 140  PRO E N     1 
ATOM   14255 C CA    . PRO E 1 140 ? -65.936  31.411   -25.305 1.00 40.29  ? 140  PRO E CA    1 
ATOM   14256 C C     . PRO E 1 140 ? -64.432  31.307   -25.067 1.00 36.83  ? 140  PRO E C     1 
ATOM   14257 O O     . PRO E 1 140 ? -63.661  31.308   -26.022 1.00 35.10  ? 140  PRO E O     1 
ATOM   14258 C CB    . PRO E 1 140 ? -66.544  32.810   -25.146 1.00 35.42  ? 140  PRO E CB    1 
ATOM   14259 C CG    . PRO E 1 140 ? -67.917  32.528   -24.498 1.00 36.29  ? 140  PRO E CG    1 
ATOM   14260 C CD    . PRO E 1 140 ? -67.790  31.256   -23.689 1.00 35.46  ? 140  PRO E CD    1 
ATOM   14261 N N     . ALA E 1 141 ? -64.025  31.182   -23.798 1.00 32.12  ? 141  ALA E N     1 
ATOM   14262 C CA    . ALA E 1 141 ? -62.612  31.038   -23.474 1.00 32.76  ? 141  ALA E CA    1 
ATOM   14263 C C     . ALA E 1 141 ? -62.101  29.641   -23.875 1.00 36.33  ? 141  ALA E C     1 
ATOM   14264 O O     . ALA E 1 141 ? -60.922  29.475   -24.247 1.00 34.26  ? 141  ALA E O     1 
ATOM   14265 C CB    . ALA E 1 141 ? -62.391  31.351   -21.989 1.00 29.79  ? 141  ALA E CB    1 
ATOM   14266 N N     . TYR E 1 142 ? -62.992  28.628   -23.781 1.00 37.35  ? 142  TYR E N     1 
ATOM   14267 C CA    . TYR E 1 142 ? -62.702  27.290   -24.286 1.00 33.50  ? 142  TYR E CA    1 
ATOM   14268 C C     . TYR E 1 142 ? -62.354  27.347   -25.783 1.00 33.31  ? 142  TYR E C     1 
ATOM   14269 O O     . TYR E 1 142 ? -61.350  26.766   -26.223 1.00 32.01  ? 142  TYR E O     1 
ATOM   14270 C CB    . TYR E 1 142 ? -63.741  26.218   -23.930 1.00 38.68  ? 142  TYR E CB    1 
ATOM   14271 C CG    . TYR E 1 142 ? -63.402  24.936   -24.685 1.00 40.50  ? 142  TYR E CG    1 
ATOM   14272 C CD1   . TYR E 1 142 ? -62.376  24.093   -24.238 1.00 34.40  ? 142  TYR E CD1   1 
ATOM   14273 C CD2   . TYR E 1 142 ? -64.061  24.597   -25.877 1.00 37.49  ? 142  TYR E CD2   1 
ATOM   14274 C CE1   . TYR E 1 142 ? -62.022  22.954   -24.939 1.00 31.99  ? 142  TYR E CE1   1 
ATOM   14275 C CE2   . TYR E 1 142 ? -63.707  23.458   -26.588 1.00 36.50  ? 142  TYR E CE2   1 
ATOM   14276 C CZ    . TYR E 1 142 ? -62.684  22.639   -26.123 1.00 35.70  ? 142  TYR E CZ    1 
ATOM   14277 O OH    . TYR E 1 142 ? -62.330  21.520   -26.831 1.00 35.80  ? 142  TYR E OH    1 
ATOM   14278 N N     . LEU E 1 143 ? -63.170  28.075   -26.562 1.00 31.25  ? 143  LEU E N     1 
ATOM   14279 C CA    . LEU E 1 143 ? -62.921  28.207   -27.990 1.00 34.19  ? 143  LEU E CA    1 
ATOM   14280 C C     . LEU E 1 143 ? -61.541  28.770   -28.268 1.00 34.88  ? 143  LEU E C     1 
ATOM   14281 O O     . LEU E 1 143 ? -60.904  28.340   -29.221 1.00 39.97  ? 143  LEU E O     1 
ATOM   14282 C CB    . LEU E 1 143 ? -64.010  28.998   -28.705 1.00 38.41  ? 143  LEU E CB    1 
ATOM   14283 C CG    . LEU E 1 143 ? -65.411  28.407   -28.592 1.00 37.76  ? 143  LEU E CG    1 
ATOM   14284 C CD1   . LEU E 1 143 ? -66.330  29.321   -29.371 1.00 34.59  ? 143  LEU E CD1   1 
ATOM   14285 C CD2   . LEU E 1 143 ? -65.451  26.989   -29.143 1.00 34.90  ? 143  LEU E CD2   1 
ATOM   14286 N N     . THR E 1 144 ? -61.056  29.675   -27.410 1.00 43.16  ? 144  THR E N     1 
ATOM   14287 C CA    . THR E 1 144 ? -59.728  30.258   -27.602 1.00 43.08  ? 144  THR E CA    1 
ATOM   14288 C C     . THR E 1 144 ? -58.663  29.178   -27.387 1.00 36.12  ? 144  THR E C     1 
ATOM   14289 O O     . THR E 1 144 ? -57.664  29.131   -28.121 1.00 32.39  ? 144  THR E O     1 
ATOM   14290 C CB    . THR E 1 144 ? -59.509  31.457   -26.667 1.00 42.92  ? 144  THR E CB    1 
ATOM   14291 O OG1   . THR E 1 144 ? -60.480  32.389   -27.118 1.00 45.93  ? 144  THR E OG1   1 
ATOM   14292 C CG2   . THR E 1 144 ? -58.151  32.123   -26.847 1.00 47.39  ? 144  THR E CG2   1 
ATOM   14293 N N     . TYR E 1 145 ? -58.879  28.349   -26.348 1.00 30.21  ? 145  TYR E N     1 
ATOM   14294 C CA    . TYR E 1 145 ? -57.954  27.287   -26.002 1.00 31.22  ? 145  TYR E CA    1 
ATOM   14295 C C     . TYR E 1 145 ? -57.918  26.235   -27.122 1.00 34.46  ? 145  TYR E C     1 
ATOM   14296 O O     . TYR E 1 145 ? -56.837  25.819   -27.555 1.00 35.33  ? 145  TYR E O     1 
ATOM   14297 C CB    . TYR E 1 145 ? -58.496  26.753   -24.681 1.00 31.96  ? 145  TYR E CB    1 
ATOM   14298 C CG    . TYR E 1 145 ? -57.861  25.476   -24.136 1.00 35.79  ? 145  TYR E CG    1 
ATOM   14299 C CD1   . TYR E 1 145 ? -56.781  25.541   -23.253 1.00 32.36  ? 145  TYR E CD1   1 
ATOM   14300 C CD2   . TYR E 1 145 ? -58.390  24.213   -24.447 1.00 29.59  ? 145  TYR E CD2   1 
ATOM   14301 C CE1   . TYR E 1 145 ? -56.240  24.388   -22.704 1.00 34.61  ? 145  TYR E CE1   1 
ATOM   14302 C CE2   . TYR E 1 145 ? -57.842  23.057   -23.909 1.00 33.80  ? 145  TYR E CE2   1 
ATOM   14303 C CZ    . TYR E 1 145 ? -56.773  23.147   -23.026 1.00 33.86  ? 145  TYR E CZ    1 
ATOM   14304 O OH    . TYR E 1 145 ? -56.240  22.032   -22.465 1.00 31.67  ? 145  TYR E OH    1 
ATOM   14305 N N     . LEU E 1 146 ? -59.110  25.835   -27.600 1.00 33.27  ? 146  LEU E N     1 
ATOM   14306 C CA    . LEU E 1 146 ? -59.215  24.881   -28.691 1.00 30.25  ? 146  LEU E CA    1 
ATOM   14307 C C     . LEU E 1 146 ? -58.446  25.421   -29.894 1.00 31.70  ? 146  LEU E C     1 
ATOM   14308 O O     . LEU E 1 146 ? -57.559  24.736   -30.454 1.00 33.53  ? 146  LEU E O     1 
ATOM   14309 C CB    . LEU E 1 146 ? -60.679  24.595   -29.018 1.00 31.37  ? 146  LEU E CB    1 
ATOM   14310 C CG    . LEU E 1 146 ? -60.940  23.795   -30.306 1.00 29.74  ? 146  LEU E CG    1 
ATOM   14311 C CD1   . LEU E 1 146 ? -60.294  22.395   -30.250 1.00 27.62  ? 146  LEU E CD1   1 
ATOM   14312 C CD2   . LEU E 1 146 ? -62.415  23.656   -30.621 1.00 25.95  ? 146  LEU E CD2   1 
ATOM   14313 N N     . GLN E 1 147 ? -58.734  26.683   -30.248 1.00 29.04  ? 147  GLN E N     1 
ATOM   14314 C CA    . GLN E 1 147 ? -58.113  27.291   -31.415 1.00 30.70  ? 147  GLN E CA    1 
ATOM   14315 C C     . GLN E 1 147 ? -56.587  27.359   -31.272 1.00 31.19  ? 147  GLN E C     1 
ATOM   14316 O O     . GLN E 1 147 ? -55.850  27.093   -32.225 1.00 33.40  ? 147  GLN E O     1 
ATOM   14317 C CB    . GLN E 1 147 ? -58.738  28.644   -31.724 1.00 30.38  ? 147  GLN E CB    1 
ATOM   14318 C CG    . GLN E 1 147 ? -58.085  29.258   -32.955 1.00 36.84  ? 147  GLN E CG    1 
ATOM   14319 C CD    . GLN E 1 147 ? -58.851  30.412   -33.550 1.00 42.05  ? 147  GLN E CD    1 
ATOM   14320 O OE1   . GLN E 1 147 ? -60.083  30.414   -33.645 1.00 49.36  ? 147  GLN E OE1   1 
ATOM   14321 N NE2   . GLN E 1 147 ? -58.088  31.397   -33.966 1.00 35.69  ? 147  GLN E NE2   1 
ATOM   14322 N N     . LYS E 1 148 ? -56.108  27.680   -30.062 1.00 33.53  ? 148  LYS E N     1 
ATOM   14323 C CA    . LYS E 1 148 ? -54.673  27.766   -29.846 1.00 35.35  ? 148  LYS E CA    1 
ATOM   14324 C C     . LYS E 1 148 ? -54.038  26.374   -30.002 1.00 33.60  ? 148  LYS E C     1 
ATOM   14325 O O     . LYS E 1 148 ? -52.931  26.250   -30.557 1.00 34.10  ? 148  LYS E O     1 
ATOM   14326 C CB    . LYS E 1 148 ? -54.457  28.376   -28.456 1.00 35.81  ? 148  LYS E CB    1 
ATOM   14327 C CG    . LYS E 1 148 ? -52.995  28.669   -28.112 1.00 43.24  ? 148  LYS E CG    1 
ATOM   14328 C CD    . LYS E 1 148 ? -52.340  29.861   -28.804 1.00 46.23  ? 148  LYS E CD    1 
ATOM   14329 C CE    . LYS E 1 148 ? -53.187  31.080   -29.065 1.00 42.18  ? 148  LYS E CE    1 
ATOM   14330 N NZ    . LYS E 1 148 ? -52.286  31.889   -29.889 1.00 41.27  ? 148  LYS E NZ    1 
ATOM   14331 N N     . SER E 1 149 ? -54.725  25.336   -29.483 1.00 32.64  ? 149  SER E N     1 
ATOM   14332 C CA    . SER E 1 149 ? -54.185  23.983   -29.562 1.00 32.62  ? 149  SER E CA    1 
ATOM   14333 C C     . SER E 1 149 ? -54.060  23.543   -31.027 1.00 31.07  ? 149  SER E C     1 
ATOM   14334 O O     . SER E 1 149 ? -53.102  22.877   -31.397 1.00 31.08  ? 149  SER E O     1 
ATOM   14335 C CB    . SER E 1 149 ? -54.965  22.991   -28.718 1.00 33.23  ? 149  SER E CB    1 
ATOM   14336 O OG    . SER E 1 149 ? -56.202  22.687   -29.348 1.00 31.17  ? 149  SER E OG    1 
ATOM   14337 N N     . VAL E 1 150 ? -54.987  24.003   -31.881 1.00 29.50  ? 150  VAL E N     1 
ATOM   14338 C CA    . VAL E 1 150 ? -54.910  23.692   -33.293 1.00 30.78  ? 150  VAL E CA    1 
ATOM   14339 C C     . VAL E 1 150 ? -53.829  24.525   -33.985 1.00 36.21  ? 150  VAL E C     1 
ATOM   14340 O O     . VAL E 1 150 ? -53.156  24.058   -34.923 1.00 36.61  ? 150  VAL E O     1 
ATOM   14341 C CB    . VAL E 1 150 ? -56.295  23.849   -33.943 1.00 30.78  ? 150  VAL E CB    1 
ATOM   14342 C CG1   . VAL E 1 150 ? -56.231  23.761   -35.470 1.00 28.34  ? 150  VAL E CG1   1 
ATOM   14343 C CG2   . VAL E 1 150 ? -57.300  22.864   -33.350 1.00 28.91  ? 150  VAL E CG2   1 
ATOM   14344 N N     . GLU E 1 151 ? -53.663  25.768   -33.520 1.00 37.29  ? 151  GLU E N     1 
ATOM   14345 C CA    . GLU E 1 151 ? -52.657  26.649   -34.091 1.00 37.78  ? 151  GLU E CA    1 
ATOM   14346 C C     . GLU E 1 151 ? -51.255  26.058   -33.904 1.00 36.94  ? 151  GLU E C     1 
ATOM   14347 O O     . GLU E 1 151 ? -50.429  26.118   -34.830 1.00 33.66  ? 151  GLU E O     1 
ATOM   14348 C CB    . GLU E 1 151 ? -52.798  28.038   -33.473 1.00 41.78  ? 151  GLU E CB    1 
ATOM   14349 C CG    . GLU E 1 151 ? -51.789  29.042   -34.032 1.00 45.58  ? 151  GLU E CG    1 
ATOM   14350 C CD    . GLU E 1 151 ? -51.767  30.394   -33.347 1.00 48.67  ? 151  GLU E CD    1 
ATOM   14351 O OE1   . GLU E 1 151 ? -52.662  30.710   -32.502 1.00 45.20  ? 151  GLU E OE1   1 
ATOM   14352 O OE2   . GLU E 1 151 ? -50.817  31.144   -33.637 1.00 50.11  ? 151  GLU E OE2   1 
ATOM   14353 N N     . VAL E 1 152 ? -50.992  25.465   -32.719 1.00 33.31  ? 152  VAL E N     1 
ATOM   14354 C CA    . VAL E 1 152 ? -49.707  24.814   -32.514 1.00 33.16  ? 152  VAL E CA    1 
ATOM   14355 C C     . VAL E 1 152 ? -49.469  23.749   -33.585 1.00 36.78  ? 152  VAL E C     1 
ATOM   14356 O O     . VAL E 1 152 ? -48.355  23.637   -34.109 1.00 33.91  ? 152  VAL E O     1 
ATOM   14357 C CB    . VAL E 1 152 ? -49.599  24.226   -31.094 1.00 34.91  ? 152  VAL E CB    1 
ATOM   14358 C CG1   . VAL E 1 152 ? -48.370  23.334   -30.913 1.00 28.16  ? 152  VAL E CG1   1 
ATOM   14359 C CG2   . VAL E 1 152 ? -49.642  25.334   -30.045 1.00 32.82  ? 152  VAL E CG2   1 
ATOM   14360 N N     . LEU E 1 153 ? -50.524  22.960   -33.890 1.00 36.47  ? 153  LEU E N     1 
ATOM   14361 C CA    . LEU E 1 153 ? -50.418  21.871   -34.852 1.00 32.98  ? 153  LEU E CA    1 
ATOM   14362 C C     . LEU E 1 153 ? -50.167  22.451   -36.238 1.00 31.89  ? 153  LEU E C     1 
ATOM   14363 O O     . LEU E 1 153 ? -49.459  21.830   -37.033 1.00 32.45  ? 153  LEU E O     1 
ATOM   14364 C CB    . LEU E 1 153 ? -51.603  20.910   -34.841 1.00 27.49  ? 153  LEU E CB    1 
ATOM   14365 C CG    . LEU E 1 153 ? -51.778  20.091   -33.553 1.00 27.64  ? 153  LEU E CG    1 
ATOM   14366 C CD1   . LEU E 1 153 ? -53.148  19.458   -33.480 1.00 29.51  ? 153  LEU E CD1   1 
ATOM   14367 C CD2   . LEU E 1 153 ? -50.715  19.035   -33.437 1.00 25.10  ? 153  LEU E CD2   1 
ATOM   14368 N N     . CYS E 1 154 ? -50.726  23.640   -36.514 1.00 29.31  ? 154  CYS E N     1 
ATOM   14369 C CA    . CYS E 1 154 ? -50.574  24.262   -37.819 1.00 29.87  ? 154  CYS E CA    1 
ATOM   14370 C C     . CYS E 1 154 ? -49.212  24.936   -38.023 1.00 32.46  ? 154  CYS E C     1 
ATOM   14371 O O     . CYS E 1 154 ? -48.885  25.296   -39.154 1.00 30.10  ? 154  CYS E O     1 
ATOM   14372 C CB    . CYS E 1 154 ? -51.577  25.378   -38.008 1.00 30.67  ? 154  CYS E CB    1 
ATOM   14373 S SG    . CYS E 1 154 ? -53.272  24.795   -38.218 1.00 36.63  ? 154  CYS E SG    1 
ATOM   14374 N N     . ARG E 1 155 ? -48.412  25.116   -36.956 1.00 34.83  ? 155  ARG E N     1 
ATOM   14375 C CA    . ARG E 1 155 ? -47.222  25.959   -37.080 1.00 39.20  ? 155  ARG E CA    1 
ATOM   14376 C C     . ARG E 1 155 ? -45.924  25.227   -36.738 1.00 41.93  ? 155  ARG E C     1 
ATOM   14377 O O     . ARG E 1 155 ? -44.864  25.758   -37.029 1.00 45.61  ? 155  ARG E O     1 
ATOM   14378 C CB    . ARG E 1 155 ? -47.304  27.235   -36.231 1.00 37.60  ? 155  ARG E CB    1 
ATOM   14379 C CG    . ARG E 1 155 ? -48.457  28.100   -36.738 1.00 44.70  ? 155  ARG E CG    1 
ATOM   14380 C CD    . ARG E 1 155 ? -48.676  29.351   -35.914 1.00 54.08  ? 155  ARG E CD    1 
ATOM   14381 N NE    . ARG E 1 155 ? -47.487  30.201   -36.082 1.00 57.68  ? 155  ARG E NE    1 
ATOM   14382 C CZ    . ARG E 1 155 ? -47.327  31.381   -35.480 1.00 61.83  ? 155  ARG E CZ    1 
ATOM   14383 N NH1   . ARG E 1 155 ? -48.155  31.767   -34.524 1.00 54.37  ? 155  ARG E NH1   1 
ATOM   14384 N NH2   . ARG E 1 155 ? -46.401  32.205   -35.912 1.00 55.61  ? 155  ARG E NH2   1 
ATOM   14385 N N     . ASN E 1 156 ? -45.972  24.022   -36.157 1.00 36.68  ? 156  ASN E N     1 
ATOM   14386 C CA    . ASN E 1 156 ? -44.741  23.444   -35.639 1.00 37.62  ? 156  ASN E CA    1 
ATOM   14387 C C     . ASN E 1 156 ? -44.338  22.134   -36.322 1.00 40.10  ? 156  ASN E C     1 
ATOM   14388 O O     . ASN E 1 156 ? -43.403  21.475   -35.864 1.00 40.90  ? 156  ASN E O     1 
ATOM   14389 C CB    . ASN E 1 156 ? -44.807  23.246   -34.134 1.00 41.36  ? 156  ASN E CB    1 
ATOM   14390 C CG    . ASN E 1 156 ? -44.712  24.568   -33.420 1.00 49.41  ? 156  ASN E CG    1 
ATOM   14391 O OD1   . ASN E 1 156 ? -45.712  25.207   -33.108 1.00 44.65  ? 156  ASN E OD1   1 
ATOM   14392 N ND2   . ASN E 1 156 ? -43.490  24.911   -33.052 1.00 54.96  ? 156  ASN E ND2   1 
ATOM   14393 N N     . TYR E 1 157 ? -45.030  21.735   -37.402 1.00 36.55  ? 157  TYR E N     1 
ATOM   14394 C CA    . TYR E 1 157 ? -44.849  20.381   -37.899 1.00 39.13  ? 157  TYR E CA    1 
ATOM   14395 C C     . TYR E 1 157 ? -44.647  20.350   -39.411 1.00 40.76  ? 157  TYR E C     1 
ATOM   14396 O O     . TYR E 1 157 ? -44.568  19.272   -39.975 1.00 44.79  ? 157  TYR E O     1 
ATOM   14397 C CB    . TYR E 1 157 ? -46.013  19.502   -37.410 1.00 36.22  ? 157  TYR E CB    1 
ATOM   14398 C CG    . TYR E 1 157 ? -46.053  19.460   -35.888 1.00 32.37  ? 157  TYR E CG    1 
ATOM   14399 C CD1   . TYR E 1 157 ? -45.131  18.702   -35.177 1.00 33.50  ? 157  TYR E CD1   1 
ATOM   14400 C CD2   . TYR E 1 157 ? -46.956  20.234   -35.162 1.00 30.95  ? 157  TYR E CD2   1 
ATOM   14401 C CE1   . TYR E 1 157 ? -45.116  18.688   -33.793 1.00 34.65  ? 157  TYR E CE1   1 
ATOM   14402 C CE2   . TYR E 1 157 ? -46.944  20.242   -33.777 1.00 29.63  ? 157  TYR E CE2   1 
ATOM   14403 C CZ    . TYR E 1 157 ? -46.023  19.459   -33.092 1.00 30.27  ? 157  TYR E CZ    1 
ATOM   14404 O OH    . TYR E 1 157 ? -45.950  19.434   -31.729 1.00 30.82  ? 157  TYR E OH    1 
ATOM   14405 N N     . GLY E 1 158 ? -44.550  21.516   -40.054 1.00 42.22  ? 158  GLY E N     1 
ATOM   14406 C CA    . GLY E 1 158 ? -44.480  21.593   -41.501 1.00 40.96  ? 158  GLY E CA    1 
ATOM   14407 C C     . GLY E 1 158 ? -45.866  21.388   -42.121 1.00 41.78  ? 158  GLY E C     1 
ATOM   14408 O O     . GLY E 1 158 ? -46.880  21.478   -41.421 1.00 39.23  ? 158  GLY E O     1 
ATOM   14409 N N     . PRO E 1 159 ? -45.950  21.122   -43.453 1.00 41.87  ? 159  PRO E N     1 
ATOM   14410 C CA    . PRO E 1 159 ? -47.239  20.918   -44.117 1.00 46.18  ? 159  PRO E CA    1 
ATOM   14411 C C     . PRO E 1 159 ? -47.992  19.701   -43.572 1.00 45.06  ? 159  PRO E C     1 
ATOM   14412 O O     . PRO E 1 159 ? -47.420  18.630   -43.383 1.00 43.91  ? 159  PRO E O     1 
ATOM   14413 C CB    . PRO E 1 159 ? -46.885  20.732   -45.605 1.00 44.41  ? 159  PRO E CB    1 
ATOM   14414 C CG    . PRO E 1 159 ? -45.418  21.061   -45.712 1.00 47.86  ? 159  PRO E CG    1 
ATOM   14415 C CD    . PRO E 1 159 ? -44.798  20.951   -44.357 1.00 46.90  ? 159  PRO E CD    1 
ATOM   14416 N N     . VAL E 1 160 ? -49.279  19.878   -43.289 1.00 39.84  ? 160  VAL E N     1 
ATOM   14417 C CA    . VAL E 1 160 ? -50.054  18.847   -42.624 1.00 41.13  ? 160  VAL E CA    1 
ATOM   14418 C C     . VAL E 1 160 ? -51.078  18.335   -43.633 1.00 41.36  ? 160  VAL E C     1 
ATOM   14419 O O     . VAL E 1 160 ? -51.669  19.121   -44.367 1.00 31.78  ? 160  VAL E O     1 
ATOM   14420 C CB    . VAL E 1 160 ? -50.692  19.578   -41.425 1.00 38.83  ? 160  VAL E CB    1 
ATOM   14421 C CG1   . VAL E 1 160 ? -51.780  18.768   -40.740 1.00 39.93  ? 160  VAL E CG1   1 
ATOM   14422 C CG2   . VAL E 1 160 ? -49.616  19.919   -40.410 1.00 34.81  ? 160  VAL E CG2   1 
ATOM   14423 N N     . GLY E 1 161 ? -51.274  17.007   -43.686 1.00 40.72  ? 161  GLY E N     1 
ATOM   14424 C CA    . GLY E 1 161 ? -52.220  16.466   -44.656 1.00 30.74  ? 161  GLY E CA    1 
ATOM   14425 C C     . GLY E 1 161 ? -53.639  16.948   -44.383 1.00 28.53  ? 161  GLY E C     1 
ATOM   14426 O O     . GLY E 1 161 ? -54.359  17.338   -45.300 1.00 37.77  ? 161  GLY E O     1 
ATOM   14427 N N     . GLY E 1 162 ? -54.032  16.964   -43.103 1.00 27.48  ? 162  GLY E N     1 
ATOM   14428 C CA    . GLY E 1 162 ? -55.394  17.334   -42.780 1.00 24.18  ? 162  GLY E CA    1 
ATOM   14429 C C     . GLY E 1 162 ? -55.672  17.300   -41.281 1.00 29.27  ? 162  GLY E C     1 
ATOM   14430 O O     . GLY E 1 162 ? -54.838  16.860   -40.490 1.00 33.70  ? 162  GLY E O     1 
ATOM   14431 N N     . PHE E 1 163 ? -56.867  17.787   -40.921 1.00 27.15  ? 163  PHE E N     1 
ATOM   14432 C CA    . PHE E 1 163 ? -57.384  17.802   -39.572 1.00 31.73  ? 163  PHE E CA    1 
ATOM   14433 C C     . PHE E 1 163 ? -58.718  17.076   -39.611 1.00 32.38  ? 163  PHE E C     1 
ATOM   14434 O O     . PHE E 1 163 ? -59.480  17.226   -40.575 1.00 31.14  ? 163  PHE E O     1 
ATOM   14435 C CB    . PHE E 1 163 ? -57.652  19.248   -39.134 1.00 34.34  ? 163  PHE E CB    1 
ATOM   14436 C CG    . PHE E 1 163 ? -56.356  19.995   -38.851 1.00 39.04  ? 163  PHE E CG    1 
ATOM   14437 C CD1   . PHE E 1 163 ? -55.798  19.983   -37.568 1.00 38.31  ? 163  PHE E CD1   1 
ATOM   14438 C CD2   . PHE E 1 163 ? -55.682  20.676   -39.871 1.00 36.98  ? 163  PHE E CD2   1 
ATOM   14439 C CE1   . PHE E 1 163 ? -54.605  20.657   -37.302 1.00 36.63  ? 163  PHE E CE1   1 
ATOM   14440 C CE2   . PHE E 1 163 ? -54.480  21.336   -39.604 1.00 35.93  ? 163  PHE E CE2   1 
ATOM   14441 C CZ    . PHE E 1 163 ? -53.940  21.333   -38.320 1.00 32.13  ? 163  PHE E CZ    1 
ATOM   14442 N N     . TRP E 1 164 ? -58.971  16.320   -38.540 1.00 28.77  ? 164  TRP E N     1 
ATOM   14443 C CA    . TRP E 1 164 ? -60.168  15.518   -38.410 1.00 27.79  ? 164  TRP E CA    1 
ATOM   14444 C C     . TRP E 1 164 ? -60.837  15.930   -37.097 1.00 27.93  ? 164  TRP E C     1 
ATOM   14445 O O     . TRP E 1 164 ? -60.359  15.605   -36.004 1.00 29.85  ? 164  TRP E O     1 
ATOM   14446 C CB    . TRP E 1 164 ? -59.722  14.043   -38.443 1.00 28.30  ? 164  TRP E CB    1 
ATOM   14447 C CG    . TRP E 1 164 ? -60.733  13.037   -38.949 1.00 28.70  ? 164  TRP E CG    1 
ATOM   14448 C CD1   . TRP E 1 164 ? -60.747  12.450   -40.186 1.00 25.85  ? 164  TRP E CD1   1 
ATOM   14449 C CD2   . TRP E 1 164 ? -61.838  12.450   -38.212 1.00 28.15  ? 164  TRP E CD2   1 
ATOM   14450 N NE1   . TRP E 1 164 ? -61.794  11.572   -40.289 1.00 27.30  ? 164  TRP E NE1   1 
ATOM   14451 C CE2   . TRP E 1 164 ? -62.486  11.544   -39.100 1.00 28.66  ? 164  TRP E CE2   1 
ATOM   14452 C CE3   . TRP E 1 164 ? -62.351  12.607   -36.916 1.00 27.13  ? 164  TRP E CE3   1 
ATOM   14453 C CZ2   . TRP E 1 164 ? -63.600  10.781   -38.719 1.00 26.68  ? 164  TRP E CZ2   1 
ATOM   14454 C CZ3   . TRP E 1 164 ? -63.450  11.847   -36.534 1.00 29.74  ? 164  TRP E CZ3   1 
ATOM   14455 C CH2   . TRP E 1 164 ? -64.057  10.937   -37.424 1.00 29.18  ? 164  TRP E CH2   1 
ATOM   14456 N N     . PHE E 1 165 ? -61.903  16.720   -37.221 1.00 29.60  ? 165  PHE E N     1 
ATOM   14457 C CA    . PHE E 1 165 ? -62.513  17.369   -36.069 1.00 30.85  ? 165  PHE E CA    1 
ATOM   14458 C C     . PHE E 1 165 ? -63.717  16.562   -35.613 1.00 31.84  ? 165  PHE E C     1 
ATOM   14459 O O     . PHE E 1 165 ? -64.600  16.230   -36.410 1.00 27.53  ? 165  PHE E O     1 
ATOM   14460 C CB    . PHE E 1 165 ? -62.963  18.817   -36.331 1.00 30.27  ? 165  PHE E CB    1 
ATOM   14461 C CG    . PHE E 1 165 ? -61.753  19.739   -36.378 1.00 28.32  ? 165  PHE E CG    1 
ATOM   14462 C CD1   . PHE E 1 165 ? -60.997  19.987   -35.226 1.00 31.81  ? 165  PHE E CD1   1 
ATOM   14463 C CD2   . PHE E 1 165 ? -61.361  20.327   -37.575 1.00 26.91  ? 165  PHE E CD2   1 
ATOM   14464 C CE1   . PHE E 1 165 ? -59.864  20.802   -35.287 1.00 34.15  ? 165  PHE E CE1   1 
ATOM   14465 C CE2   . PHE E 1 165 ? -60.250  21.180   -37.614 1.00 30.13  ? 165  PHE E CE2   1 
ATOM   14466 C CZ    . PHE E 1 165 ? -59.498  21.417   -36.471 1.00 27.04  ? 165  PHE E CZ    1 
ATOM   14467 N N     . ASP E 1 166 ? -63.773  16.313   -34.310 1.00 28.05  ? 166  ASP E N     1 
ATOM   14468 C CA    . ASP E 1 166 ? -64.846  15.508   -33.782 1.00 28.94  ? 166  ASP E CA    1 
ATOM   14469 C C     . ASP E 1 166 ? -65.408  16.138   -32.507 1.00 34.69  ? 166  ASP E C     1 
ATOM   14470 O O     . ASP E 1 166 ? -64.689  16.281   -31.509 1.00 37.28  ? 166  ASP E O     1 
ATOM   14471 C CB    . ASP E 1 166 ? -64.295  14.120   -33.497 1.00 35.49  ? 166  ASP E CB    1 
ATOM   14472 C CG    . ASP E 1 166 ? -65.252  13.208   -32.747 1.00 39.83  ? 166  ASP E CG    1 
ATOM   14473 O OD1   . ASP E 1 166 ? -66.444  13.215   -33.117 1.00 39.81  ? 166  ASP E OD1   1 
ATOM   14474 O OD2   . ASP E 1 166 ? -64.807  12.529   -31.796 1.00 38.35  ? 166  ASP E OD2   1 
ATOM   14475 N N     . GLY E 1 167 ? -66.712  16.466   -32.482 1.00 37.12  ? 167  GLY E N     1 
ATOM   14476 C CA    . GLY E 1 167 ? -67.321  16.656   -31.169 1.00 38.53  ? 167  GLY E CA    1 
ATOM   14477 C C     . GLY E 1 167 ? -68.197  17.909   -31.020 1.00 48.96  ? 167  GLY E C     1 
ATOM   14478 O O     . GLY E 1 167 ? -68.723  18.186   -29.929 1.00 45.26  ? 167  GLY E O     1 
ATOM   14479 N N     . ASN E 1 168 ? -68.359  18.669   -32.111 1.00 47.83  ? 168  ASN E N     1 
ATOM   14480 C CA    . ASN E 1 168 ? -69.255  19.815   -32.123 1.00 42.54  ? 168  ASN E CA    1 
ATOM   14481 C C     . ASN E 1 168 ? -70.685  19.364   -31.825 1.00 47.88  ? 168  ASN E C     1 
ATOM   14482 O O     . ASN E 1 168 ? -71.494  20.134   -31.312 1.00 40.44  ? 168  ASN E O     1 
ATOM   14483 C CB    . ASN E 1 168 ? -69.175  20.642   -33.406 1.00 45.22  ? 168  ASN E CB    1 
ATOM   14484 C CG    . ASN E 1 168 ? -67.860  21.377   -33.593 1.00 45.27  ? 168  ASN E CG    1 
ATOM   14485 O OD1   . ASN E 1 168 ? -67.788  22.282   -34.433 1.00 46.23  ? 168  ASN E OD1   1 
ATOM   14486 N ND2   . ASN E 1 168 ? -66.812  21.044   -32.844 1.00 43.37  ? 168  ASN E ND2   1 
ATOM   14487 N N     . TRP E 1 169 ? -70.974  18.085   -32.122 1.00 47.23  ? 169  TRP E N     1 
ATOM   14488 C CA    . TRP E 1 169 ? -72.259  17.442   -31.862 1.00 48.72  ? 169  TRP E CA    1 
ATOM   14489 C C     . TRP E 1 169 ? -72.624  17.472   -30.376 1.00 49.69  ? 169  TRP E C     1 
ATOM   14490 O O     . TRP E 1 169 ? -73.793  17.254   -30.044 1.00 51.26  ? 169  TRP E O     1 
ATOM   14491 C CB    . TRP E 1 169 ? -72.257  16.005   -32.415 1.00 50.65  ? 169  TRP E CB    1 
ATOM   14492 C CG    . TRP E 1 169 ? -70.988  15.240   -32.118 1.00 49.13  ? 169  TRP E CG    1 
ATOM   14493 C CD1   . TRP E 1 169 ? -69.961  15.003   -32.992 1.00 42.12  ? 169  TRP E CD1   1 
ATOM   14494 C CD2   . TRP E 1 169 ? -70.589  14.665   -30.847 1.00 41.29  ? 169  TRP E CD2   1 
ATOM   14495 N NE1   . TRP E 1 169 ? -68.964  14.300   -32.366 1.00 40.42  ? 169  TRP E NE1   1 
ATOM   14496 C CE2   . TRP E 1 169 ? -69.315  14.071   -31.058 1.00 41.44  ? 169  TRP E CE2   1 
ATOM   14497 C CE3   . TRP E 1 169 ? -71.177  14.590   -29.576 1.00 39.52  ? 169  TRP E CE3   1 
ATOM   14498 C CZ2   . TRP E 1 169 ? -68.624  13.405   -30.044 1.00 38.96  ? 169  TRP E CZ2   1 
ATOM   14499 C CZ3   . TRP E 1 169 ? -70.494  13.961   -28.559 1.00 48.39  ? 169  TRP E CZ3   1 
ATOM   14500 C CH2   . TRP E 1 169 ? -69.229  13.396   -28.799 1.00 52.84  ? 169  TRP E CH2   1 
ATOM   14501 N N     . ASN E 1 170 ? -71.643  17.733   -29.485 1.00 47.34  ? 170  ASN E N     1 
ATOM   14502 C CA    . ASN E 1 170 ? -71.935  17.783   -28.061 1.00 43.14  ? 170  ASN E CA    1 
ATOM   14503 C C     . ASN E 1 170 ? -72.776  19.020   -27.707 1.00 48.54  ? 170  ASN E C     1 
ATOM   14504 O O     . ASN E 1 170 ? -73.563  18.987   -26.760 1.00 39.20  ? 170  ASN E O     1 
ATOM   14505 C CB    . ASN E 1 170 ? -70.690  17.678   -27.202 1.00 47.18  ? 170  ASN E CB    1 
ATOM   14506 C CG    . ASN E 1 170 ? -71.026  17.880   -25.736 1.00 52.26  ? 170  ASN E CG    1 
ATOM   14507 O OD1   . ASN E 1 170 ? -71.597  16.975   -25.127 1.00 51.18  ? 170  ASN E OD1   1 
ATOM   14508 N ND2   . ASN E 1 170 ? -70.701  19.027   -25.142 1.00 44.84  ? 170  ASN E ND2   1 
ATOM   14509 N N     . LYS E 1 171 ? -72.573  20.136   -28.422 1.00 47.97  ? 171  LYS E N     1 
ATOM   14510 C CA    . LYS E 1 171 ? -73.383  21.338   -28.245 1.00 48.97  ? 171  LYS E CA    1 
ATOM   14511 C C     . LYS E 1 171 ? -73.866  21.782   -29.623 1.00 51.67  ? 171  LYS E C     1 
ATOM   14512 O O     . LYS E 1 171 ? -73.238  22.632   -30.252 1.00 41.26  ? 171  LYS E O     1 
ATOM   14513 C CB    . LYS E 1 171 ? -72.533  22.448   -27.603 1.00 50.50  ? 171  LYS E CB    1 
ATOM   14514 C CG    . LYS E 1 171 ? -72.095  22.235   -26.165 1.00 54.13  ? 171  LYS E CG    1 
ATOM   14515 C CD    . LYS E 1 171 ? -71.256  23.354   -25.556 1.00 59.84  ? 171  LYS E CD    1 
ATOM   14516 C CE    . LYS E 1 171 ? -71.695  23.690   -24.154 1.00 60.96  ? 171  LYS E CE    1 
ATOM   14517 N NZ    . LYS E 1 171 ? -70.598  23.923   -23.192 1.00 68.42  ? 171  LYS E NZ    1 
ATOM   14518 N N     . LYS E 1 172 ? -74.975  21.192   -30.097 1.00 70.80  ? 172  LYS E N     1 
ATOM   14519 C CA    . LYS E 1 172 ? -75.453  21.386   -31.467 1.00 72.71  ? 172  LYS E CA    1 
ATOM   14520 C C     . LYS E 1 172 ? -75.863  22.849   -31.683 1.00 78.55  ? 172  LYS E C     1 
ATOM   14521 O O     . LYS E 1 172 ? -75.817  23.335   -32.815 1.00 62.29  ? 172  LYS E O     1 
ATOM   14522 C CB    . LYS E 1 172 ? -76.626  20.480   -31.870 1.00 69.25  ? 172  LYS E CB    1 
ATOM   14523 C CG    . LYS E 1 172 ? -76.411  18.988   -31.774 1.00 81.88  ? 172  LYS E CG    1 
ATOM   14524 C CD    . LYS E 1 172 ? -77.664  18.171   -32.056 1.00 87.04  ? 172  LYS E CD    1 
ATOM   14525 C CE    . LYS E 1 172 ? -77.423  16.687   -31.897 1.00 88.76  ? 172  LYS E CE    1 
ATOM   14526 N NZ    . LYS E 1 172 ? -76.284  16.175   -32.678 1.00 62.85  ? 172  LYS E NZ    1 
ATOM   14527 N N     . ASP E 1 173 ? -76.241  23.552   -30.591 1.00 79.97  ? 173  ASP E N     1 
ATOM   14528 C CA    . ASP E 1 173 ? -76.816  24.886   -30.679 1.00 80.83  ? 173  ASP E CA    1 
ATOM   14529 C C     . ASP E 1 173 ? -75.777  26.004   -30.535 1.00 76.55  ? 173  ASP E C     1 
ATOM   14530 O O     . ASP E 1 173 ? -76.062  27.140   -30.883 1.00 69.37  ? 173  ASP E O     1 
ATOM   14531 C CB    . ASP E 1 173 ? -78.022  25.006   -29.761 1.00 87.67  ? 173  ASP E CB    1 
ATOM   14532 C CG    . ASP E 1 173 ? -79.242  24.224   -30.223 1.00 89.27  ? 173  ASP E CG    1 
ATOM   14533 O OD1   . ASP E 1 173 ? -79.280  23.775   -31.401 1.00 74.43  ? 173  ASP E OD1   1 
ATOM   14534 O OD2   . ASP E 1 173 ? -80.141  24.069   -29.393 1.00 87.59  ? 173  ASP E OD2   1 
ATOM   14535 N N     . ALA E 1 174 ? -74.575  25.701   -30.031 1.00 67.89  ? 174  ALA E N     1 
ATOM   14536 C CA    . ALA E 1 174 ? -73.603  26.722   -29.675 1.00 55.83  ? 174  ALA E CA    1 
ATOM   14537 C C     . ALA E 1 174 ? -72.960  27.317   -30.921 1.00 45.87  ? 174  ALA E C     1 
ATOM   14538 O O     . ALA E 1 174 ? -72.961  26.712   -31.986 1.00 40.24  ? 174  ALA E O     1 
ATOM   14539 C CB    . ALA E 1 174 ? -72.563  26.143   -28.753 1.00 56.06  ? 174  ALA E CB    1 
ATOM   14540 N N     . ASP E 1 175 ? -72.422  28.533   -30.759 1.00 42.95  ? 175  ASP E N     1 
ATOM   14541 C CA    . ASP E 1 175 ? -71.603  29.140   -31.786 1.00 48.44  ? 175  ASP E CA    1 
ATOM   14542 C C     . ASP E 1 175 ? -70.168  28.658   -31.574 1.00 46.46  ? 175  ASP E C     1 
ATOM   14543 O O     . ASP E 1 175 ? -69.546  29.015   -30.591 1.00 48.69  ? 175  ASP E O     1 
ATOM   14544 C CB    . ASP E 1 175 ? -71.750  30.654   -31.780 1.00 48.07  ? 175  ASP E CB    1 
ATOM   14545 C CG    . ASP E 1 175 ? -71.002  31.414   -32.878 1.00 54.87  ? 175  ASP E CG    1 
ATOM   14546 O OD1   . ASP E 1 175 ? -70.205  30.800   -33.610 1.00 51.65  ? 175  ASP E OD1   1 
ATOM   14547 O OD2   . ASP E 1 175 ? -71.236  32.632   -33.031 1.00 59.39  ? 175  ASP E OD2   1 
ATOM   14548 N N     . TRP E 1 176 ? -69.652  27.863   -32.518 1.00 45.07  ? 176  TRP E N     1 
ATOM   14549 C CA    . TRP E 1 176 ? -68.326  27.276   -32.422 1.00 39.05  ? 176  TRP E CA    1 
ATOM   14550 C C     . TRP E 1 176 ? -67.264  28.145   -33.083 1.00 39.13  ? 176  TRP E C     1 
ATOM   14551 O O     . TRP E 1 176 ? -66.075  27.788   -33.032 1.00 39.25  ? 176  TRP E O     1 
ATOM   14552 C CB    . TRP E 1 176 ? -68.293  25.851   -33.002 1.00 34.83  ? 176  TRP E CB    1 
ATOM   14553 C CG    . TRP E 1 176 ? -68.901  24.820   -32.084 1.00 34.40  ? 176  TRP E CG    1 
ATOM   14554 C CD1   . TRP E 1 176 ? -70.208  24.441   -32.035 1.00 32.97  ? 176  TRP E CD1   1 
ATOM   14555 C CD2   . TRP E 1 176 ? -68.211  24.032   -31.087 1.00 33.46  ? 176  TRP E CD2   1 
ATOM   14556 N NE1   . TRP E 1 176 ? -70.392  23.515   -31.048 1.00 35.59  ? 176  TRP E NE1   1 
ATOM   14557 C CE2   . TRP E 1 176 ? -69.184  23.218   -30.471 1.00 33.64  ? 176  TRP E CE2   1 
ATOM   14558 C CE3   . TRP E 1 176 ? -66.872  23.932   -30.668 1.00 34.90  ? 176  TRP E CE3   1 
ATOM   14559 C CZ2   . TRP E 1 176 ? -68.870  22.314   -29.454 1.00 32.30  ? 176  TRP E CZ2   1 
ATOM   14560 C CZ3   . TRP E 1 176 ? -66.566  23.036   -29.663 1.00 33.84  ? 176  TRP E CZ3   1 
ATOM   14561 C CH2   . TRP E 1 176 ? -67.547  22.232   -29.077 1.00 33.15  ? 176  TRP E CH2   1 
ATOM   14562 N N     . HIS E 1 177 ? -67.684  29.255   -33.711 1.00 36.26  ? 177  HIS E N     1 
ATOM   14563 C CA    . HIS E 1 177 ? -66.727  30.190   -34.295 1.00 43.33  ? 177  HIS E CA    1 
ATOM   14564 C C     . HIS E 1 177 ? -65.844  29.450   -35.303 1.00 44.52  ? 177  HIS E C     1 
ATOM   14565 O O     . HIS E 1 177 ? -64.611  29.559   -35.290 1.00 41.59  ? 177  HIS E O     1 
ATOM   14566 C CB    . HIS E 1 177 ? -65.953  30.981   -33.216 1.00 49.87  ? 177  HIS E CB    1 
ATOM   14567 C CG    . HIS E 1 177 ? -66.782  31.974   -32.443 1.00 56.25  ? 177  HIS E CG    1 
ATOM   14568 N ND1   . HIS E 1 177 ? -67.055  33.281   -32.815 1.00 61.05  ? 177  HIS E ND1   1 
ATOM   14569 C CD2   . HIS E 1 177 ? -67.454  31.775   -31.300 1.00 52.23  ? 177  HIS E CD2   1 
ATOM   14570 C CE1   . HIS E 1 177 ? -67.872  33.833   -31.927 1.00 55.00  ? 177  HIS E CE1   1 
ATOM   14571 N NE2   . HIS E 1 177 ? -68.114  32.936   -30.985 1.00 58.16  ? 177  HIS E NE2   1 
ATOM   14572 N N     . LEU E 1 178 ? -66.508  28.721   -36.206 1.00 46.36  ? 178  LEU E N     1 
ATOM   14573 C CA    . LEU E 1 178 ? -65.810  27.930   -37.208 1.00 45.06  ? 178  LEU E CA    1 
ATOM   14574 C C     . LEU E 1 178 ? -65.088  28.825   -38.210 1.00 42.91  ? 178  LEU E C     1 
ATOM   14575 O O     . LEU E 1 178 ? -63.959  28.499   -38.592 1.00 43.69  ? 178  LEU E O     1 
ATOM   14576 C CB    . LEU E 1 178 ? -66.729  26.896   -37.869 1.00 44.08  ? 178  LEU E CB    1 
ATOM   14577 C CG    . LEU E 1 178 ? -67.330  25.874   -36.894 1.00 38.77  ? 178  LEU E CG    1 
ATOM   14578 C CD1   . LEU E 1 178 ? -68.295  24.934   -37.594 1.00 32.34  ? 178  LEU E CD1   1 
ATOM   14579 C CD2   . LEU E 1 178 ? -66.205  25.092   -36.190 1.00 38.38  ? 178  LEU E CD2   1 
ATOM   14580 N N     . PRO E 1 179 ? -65.685  29.956   -38.679 1.00 43.91  ? 179  PRO E N     1 
ATOM   14581 C CA    . PRO E 1 179 ? -64.963  30.870   -39.579 1.00 42.60  ? 179  PRO E CA    1 
ATOM   14582 C C     . PRO E 1 179 ? -63.569  31.231   -39.063 1.00 42.91  ? 179  PRO E C     1 
ATOM   14583 O O     . PRO E 1 179 ? -62.602  31.211   -39.828 1.00 43.83  ? 179  PRO E O     1 
ATOM   14584 C CB    . PRO E 1 179 ? -65.944  32.026   -39.836 1.00 39.91  ? 179  PRO E CB    1 
ATOM   14585 C CG    . PRO E 1 179 ? -67.316  31.399   -39.545 1.00 37.19  ? 179  PRO E CG    1 
ATOM   14586 C CD    . PRO E 1 179 ? -67.088  30.368   -38.451 1.00 39.47  ? 179  PRO E CD    1 
ATOM   14587 N N     . GLU E 1 180 ? -63.462  31.472   -37.751 1.00 41.29  ? 180  GLU E N     1 
ATOM   14588 C CA    . GLU E 1 180 ? -62.191  31.865   -37.151 1.00 50.02  ? 180  GLU E CA    1 
ATOM   14589 C C     . GLU E 1 180 ? -61.242  30.671   -37.042 1.00 42.53  ? 180  GLU E C     1 
ATOM   14590 O O     . GLU E 1 180 ? -60.053  30.808   -37.346 1.00 39.21  ? 180  GLU E O     1 
ATOM   14591 C CB    . GLU E 1 180 ? -62.287  32.654   -35.834 1.00 55.76  ? 180  GLU E CB    1 
ATOM   14592 C CG    . GLU E 1 180 ? -63.227  33.861   -35.907 1.00 58.32  ? 180  GLU E CG    1 
ATOM   14593 C CD    . GLU E 1 180 ? -64.683  33.657   -35.514 1.00 64.08  ? 180  GLU E CD    1 
ATOM   14594 O OE1   . GLU E 1 180 ? -65.533  33.023   -36.186 1.00 61.27  ? 180  GLU E OE1   1 
ATOM   14595 O OE2   . GLU E 1 180 ? -64.973  34.190   -34.414 1.00 67.04  ? 180  GLU E OE2   1 
ATOM   14596 N N     . LEU E 1 181 ? -61.762  29.513   -36.595 1.00 42.79  ? 181  LEU E N     1 
ATOM   14597 C CA    . LEU E 1 181 ? -60.938  28.309   -36.462 1.00 38.15  ? 181  LEU E CA    1 
ATOM   14598 C C     . LEU E 1 181 ? -60.417  27.866   -37.834 1.00 33.70  ? 181  LEU E C     1 
ATOM   14599 O O     . LEU E 1 181 ? -59.209  27.722   -38.019 1.00 35.61  ? 181  LEU E O     1 
ATOM   14600 C CB    . LEU E 1 181 ? -61.714  27.190   -35.769 1.00 34.34  ? 181  LEU E CB    1 
ATOM   14601 C CG    . LEU E 1 181 ? -60.982  25.858   -35.615 1.00 37.41  ? 181  LEU E CG    1 
ATOM   14602 C CD1   . LEU E 1 181 ? -59.716  25.993   -34.745 1.00 34.43  ? 181  LEU E CD1   1 
ATOM   14603 C CD2   . LEU E 1 181 ? -61.995  24.858   -35.009 1.00 34.44  ? 181  LEU E CD2   1 
ATOM   14604 N N     . TYR E 1 182 ? -61.309  27.642   -38.764 1.00 32.55  ? 182  TYR E N     1 
ATOM   14605 C CA    . TYR E 1 182 ? -60.951  27.184   -40.086 1.00 35.51  ? 182  TYR E CA    1 
ATOM   14606 C C     . TYR E 1 182 ? -60.167  28.208   -40.843 1.00 44.23  ? 182  TYR E C     1 
ATOM   14607 O O     . TYR E 1 182 ? -59.344  27.893   -41.655 1.00 42.84  ? 182  TYR E O     1 
ATOM   14608 C CB    . TYR E 1 182 ? -62.155  26.692   -40.853 1.00 36.30  ? 182  TYR E CB    1 
ATOM   14609 C CG    . TYR E 1 182 ? -62.855  25.558   -40.189 1.00 36.72  ? 182  TYR E CG    1 
ATOM   14610 C CD1   . TYR E 1 182 ? -62.221  24.787   -39.252 1.00 36.13  ? 182  TYR E CD1   1 
ATOM   14611 C CD2   . TYR E 1 182 ? -64.139  25.251   -40.505 1.00 35.91  ? 182  TYR E CD2   1 
ATOM   14612 C CE1   . TYR E 1 182 ? -62.861  23.750   -38.648 1.00 35.45  ? 182  TYR E CE1   1 
ATOM   14613 C CE2   . TYR E 1 182 ? -64.785  24.214   -39.900 1.00 38.60  ? 182  TYR E CE2   1 
ATOM   14614 C CZ    . TYR E 1 182 ? -64.134  23.463   -38.979 1.00 37.11  ? 182  TYR E CZ    1 
ATOM   14615 O OH    . TYR E 1 182 ? -64.758  22.448   -38.369 1.00 34.54  ? 182  TYR E OH    1 
ATOM   14616 N N     . GLY E 1 183 ? -60.486  29.460   -40.608 1.00 46.46  ? 183  GLY E N     1 
ATOM   14617 C CA    . GLY E 1 183 ? -59.776  30.538   -41.227 1.00 40.75  ? 183  GLY E CA    1 
ATOM   14618 C C     . GLY E 1 183 ? -58.338  30.568   -40.820 1.00 34.35  ? 183  GLY E C     1 
ATOM   14619 O O     . GLY E 1 183 ? -57.498  30.885   -41.604 1.00 38.76  ? 183  GLY E O     1 
ATOM   14620 N N     . MET E 1 184 ? -58.065  30.302   -39.567 1.00 31.74  ? 184  MET E N     1 
ATOM   14621 C CA    . MET E 1 184 ? -56.703  30.257   -39.125 1.00 35.12  ? 184  MET E CA    1 
ATOM   14622 C C     . MET E 1 184 ? -55.961  29.100   -39.753 1.00 40.17  ? 184  MET E C     1 
ATOM   14623 O O     . MET E 1 184 ? -54.821  29.214   -40.054 1.00 38.99  ? 184  MET E O     1 
ATOM   14624 C CB    . MET E 1 184 ? -56.580  30.314   -37.615 1.00 40.20  ? 184  MET E CB    1 
ATOM   14625 C CG    . MET E 1 184 ? -56.548  29.007   -36.884 1.00 68.99  ? 184  MET E CG    1 
ATOM   14626 S SD    . MET E 1 184 ? -54.925  28.329   -36.687 1.00 59.91  ? 184  MET E SD    1 
ATOM   14627 C CE    . MET E 1 184 ? -54.284  29.720   -35.830 1.00 73.48  ? 184  MET E CE    1 
ATOM   14628 N N     . ILE E 1 185 ? -56.623  27.970   -39.908 1.00 40.84  ? 185  ILE E N     1 
ATOM   14629 C CA    . ILE E 1 185 ? -56.023  26.816   -40.523 1.00 40.70  ? 185  ILE E CA    1 
ATOM   14630 C C     . ILE E 1 185 ? -55.669  27.118   -41.963 1.00 33.89  ? 185  ILE E C     1 
ATOM   14631 O O     . ILE E 1 185 ? -54.636  26.756   -42.403 1.00 34.71  ? 185  ILE E O     1 
ATOM   14632 C CB    . ILE E 1 185 ? -56.941  25.592   -40.451 1.00 39.14  ? 185  ILE E CB    1 
ATOM   14633 C CG1   . ILE E 1 185 ? -57.062  25.089   -39.039 1.00 32.02  ? 185  ILE E CG1   1 
ATOM   14634 C CG2   . ILE E 1 185 ? -56.383  24.477   -41.279 1.00 39.83  ? 185  ILE E CG2   1 
ATOM   14635 C CD1   . ILE E 1 185 ? -58.015  23.958   -38.882 1.00 31.77  ? 185  ILE E CD1   1 
ATOM   14636 N N     . ARG E 1 186 ? -56.538  27.796   -42.674 1.00 32.28  ? 186  ARG E N     1 
ATOM   14637 C CA    . ARG E 1 186 ? -56.259  28.172   -44.033 1.00 41.84  ? 186  ARG E CA    1 
ATOM   14638 C C     . ARG E 1 186 ? -55.107  29.129   -44.134 1.00 42.88  ? 186  ARG E C     1 
ATOM   14639 O O     . ARG E 1 186 ? -54.373  29.084   -45.074 1.00 48.69  ? 186  ARG E O     1 
ATOM   14640 C CB    . ARG E 1 186 ? -57.463  28.765   -44.706 1.00 41.87  ? 186  ARG E CB    1 
ATOM   14641 C CG    . ARG E 1 186 ? -58.522  27.759   -45.000 1.00 47.10  ? 186  ARG E CG    1 
ATOM   14642 C CD    . ARG E 1 186 ? -58.238  26.902   -46.211 1.00 50.59  ? 186  ARG E CD    1 
ATOM   14643 N NE    . ARG E 1 186 ? -59.186  25.812   -46.197 1.00 43.23  ? 186  ARG E NE    1 
ATOM   14644 C CZ    . ARG E 1 186 ? -58.891  24.532   -46.220 1.00 40.54  ? 186  ARG E CZ    1 
ATOM   14645 N NH1   . ARG E 1 186 ? -57.669  24.109   -46.340 1.00 34.84  ? 186  ARG E NH1   1 
ATOM   14646 N NH2   . ARG E 1 186 ? -59.851  23.678   -46.152 1.00 39.86  ? 186  ARG E NH2   1 
ATOM   14647 N N     . HIS E 1 187 ? -54.980  30.043   -43.198 1.00 44.13  ? 187  HIS E N     1 
ATOM   14648 C CA    . HIS E 1 187 ? -53.870  30.941   -43.268 1.00 47.76  ? 187  HIS E CA    1 
ATOM   14649 C C     . HIS E 1 187 ? -52.527  30.230   -43.151 1.00 45.21  ? 187  HIS E C     1 
ATOM   14650 O O     . HIS E 1 187 ? -51.665  30.422   -43.963 1.00 43.85  ? 187  HIS E O     1 
ATOM   14651 C CB    . HIS E 1 187 ? -54.008  32.012   -42.199 1.00 53.68  ? 187  HIS E CB    1 
ATOM   14652 C CG    . HIS E 1 187 ? -52.870  32.969   -42.169 1.00 63.89  ? 187  HIS E CG    1 
ATOM   14653 N ND1   . HIS E 1 187 ? -51.978  33.016   -41.132 1.00 70.25  ? 187  HIS E ND1   1 
ATOM   14654 C CD2   . HIS E 1 187 ? -52.456  33.888   -43.063 1.00 61.22  ? 187  HIS E CD2   1 
ATOM   14655 C CE1   . HIS E 1 187 ? -51.067  33.931   -41.381 1.00 69.74  ? 187  HIS E CE1   1 
ATOM   14656 N NE2   . HIS E 1 187 ? -51.330  34.468   -42.550 1.00 64.63  ? 187  HIS E NE2   1 
ATOM   14657 N N     . TYR E 1 188 ? -52.387  29.345   -42.186 1.00 49.39  ? 188  TYR E N     1 
ATOM   14658 C CA    . TYR E 1 188 ? -51.150  28.610   -41.986 1.00 41.62  ? 188  TYR E CA    1 
ATOM   14659 C C     . TYR E 1 188 ? -50.955  27.332   -42.762 1.00 43.45  ? 188  TYR E C     1 
ATOM   14660 O O     . TYR E 1 188 ? -49.850  26.954   -43.023 1.00 39.68  ? 188  TYR E O     1 
ATOM   14661 C CB    . TYR E 1 188 ? -50.982  28.282   -40.524 1.00 44.16  ? 188  TYR E CB    1 
ATOM   14662 C CG    . TYR E 1 188 ? -50.791  29.478   -39.671 1.00 55.04  ? 188  TYR E CG    1 
ATOM   14663 C CD1   . TYR E 1 188 ? -49.642  30.219   -39.742 1.00 55.67  ? 188  TYR E CD1   1 
ATOM   14664 C CD2   . TYR E 1 188 ? -51.757  29.868   -38.797 1.00 51.94  ? 188  TYR E CD2   1 
ATOM   14665 C CE1   . TYR E 1 188 ? -49.474  31.323   -38.962 1.00 58.83  ? 188  TYR E CE1   1 
ATOM   14666 C CE2   . TYR E 1 188 ? -51.598  30.960   -38.018 1.00 54.16  ? 188  TYR E CE2   1 
ATOM   14667 C CZ    . TYR E 1 188 ? -50.460  31.682   -38.108 1.00 63.23  ? 188  TYR E CZ    1 
ATOM   14668 O OH    . TYR E 1 188 ? -50.342  32.771   -37.320 1.00 60.44  ? 188  TYR E OH    1 
ATOM   14669 N N     . GLN E 1 189 ? -52.048  26.689   -43.131 1.00 42.33  ? 189  GLN E N     1 
ATOM   14670 C CA    . GLN E 1 189 ? -52.017  25.392   -43.793 1.00 40.28  ? 189  GLN E CA    1 
ATOM   14671 C C     . GLN E 1 189 ? -52.993  25.430   -44.959 1.00 41.61  ? 189  GLN E C     1 
ATOM   14672 O O     . GLN E 1 189 ? -53.996  24.723   -44.926 1.00 45.92  ? 189  GLN E O     1 
ATOM   14673 C CB    . GLN E 1 189 ? -52.412  24.312   -42.786 1.00 35.82  ? 189  GLN E CB    1 
ATOM   14674 C CG    . GLN E 1 189 ? -51.394  24.088   -41.681 1.00 32.69  ? 189  GLN E CG    1 
ATOM   14675 C CD    . GLN E 1 189 ? -50.180  23.330   -42.162 1.00 38.83  ? 189  GLN E CD    1 
ATOM   14676 O OE1   . GLN E 1 189 ? -50.262  22.576   -43.134 1.00 39.49  ? 189  GLN E OE1   1 
ATOM   14677 N NE2   . GLN E 1 189 ? -49.062  23.440   -41.443 1.00 37.84  ? 189  GLN E NE2   1 
ATOM   14678 N N     . PRO E 1 190 ? -52.753  26.257   -46.009 1.00 48.65  ? 190  PRO E N     1 
ATOM   14679 C CA    . PRO E 1 190 ? -53.745  26.431   -47.077 1.00 47.85  ? 190  PRO E CA    1 
ATOM   14680 C C     . PRO E 1 190 ? -54.170  25.114   -47.736 1.00 44.29  ? 190  PRO E C     1 
ATOM   14681 O O     . PRO E 1 190 ? -55.295  24.983   -48.210 1.00 41.70  ? 190  PRO E O     1 
ATOM   14682 C CB    . PRO E 1 190 ? -53.094  27.433   -48.052 1.00 42.14  ? 190  PRO E CB    1 
ATOM   14683 C CG    . PRO E 1 190 ? -51.602  27.322   -47.737 1.00 42.17  ? 190  PRO E CG    1 
ATOM   14684 C CD    . PRO E 1 190 ? -51.493  26.987   -46.260 1.00 41.80  ? 190  PRO E CD    1 
ATOM   14685 N N     . ASN E 1 191 ? -53.263  24.127   -47.709 1.00 46.16  ? 191  ASN E N     1 
ATOM   14686 C CA    . ASN E 1 191 ? -53.430  22.873   -48.420 1.00 52.08  ? 191  ASN E CA    1 
ATOM   14687 C C     . ASN E 1 191 ? -54.004  21.732   -47.558 1.00 50.19  ? 191  ASN E C     1 
ATOM   14688 O O     . ASN E 1 191 ? -54.212  20.634   -48.056 1.00 51.97  ? 191  ASN E O     1 
ATOM   14689 C CB    . ASN E 1 191 ? -52.097  22.494   -49.051 1.00 46.11  ? 191  ASN E CB    1 
ATOM   14690 C CG    . ASN E 1 191 ? -52.327  21.526   -50.182 1.00 57.77  ? 191  ASN E CG    1 
ATOM   14691 O OD1   . ASN E 1 191 ? -51.734  20.433   -50.186 1.00 53.32  ? 191  ASN E OD1   1 
ATOM   14692 N ND2   . ASN E 1 191 ? -53.239  21.873   -51.089 1.00 46.65  ? 191  ASN E ND2   1 
ATOM   14693 N N     . ALA E 1 192 ? -54.267  21.968   -46.271 1.00 48.18  ? 192  ALA E N     1 
ATOM   14694 C CA    . ALA E 1 192 ? -54.720  20.912   -45.373 1.00 44.99  ? 192  ALA E CA    1 
ATOM   14695 C C     . ALA E 1 192 ? -56.155  20.521   -45.711 1.00 39.55  ? 192  ALA E C     1 
ATOM   14696 O O     . ALA E 1 192 ? -56.965  21.381   -46.040 1.00 41.72  ? 192  ALA E O     1 
ATOM   14697 C CB    . ALA E 1 192 ? -54.612  21.379   -43.935 1.00 38.82  ? 192  ALA E CB    1 
ATOM   14698 N N     . ILE E 1 193 ? -56.462  19.219   -45.649 1.00 38.36  ? 193  ILE E N     1 
ATOM   14699 C CA    . ILE E 1 193 ? -57.845  18.775   -45.767 1.00 34.85  ? 193  ILE E CA    1 
ATOM   14700 C C     . ILE E 1 193 ? -58.526  18.960   -44.415 1.00 32.21  ? 193  ILE E C     1 
ATOM   14701 O O     . ILE E 1 193 ? -58.001  18.521   -43.397 1.00 33.45  ? 193  ILE E O     1 
ATOM   14702 C CB    . ILE E 1 193 ? -57.881  17.308   -46.216 1.00 34.52  ? 193  ILE E CB    1 
ATOM   14703 C CG1   . ILE E 1 193 ? -57.458  17.144   -47.689 1.00 35.14  ? 193  ILE E CG1   1 
ATOM   14704 C CG2   . ILE E 1 193 ? -59.253  16.691   -45.947 1.00 34.76  ? 193  ILE E CG2   1 
ATOM   14705 C CD1   . ILE E 1 193 ? -58.483  17.665   -48.674 1.00 29.78  ? 193  ILE E CD1   1 
ATOM   14706 N N     . ILE E 1 194 ? -59.675  19.638   -44.389 1.00 32.19  ? 194  ILE E N     1 
ATOM   14707 C CA    . ILE E 1 194 ? -60.434  19.761   -43.154 1.00 34.64  ? 194  ILE E CA    1 
ATOM   14708 C C     . ILE E 1 194 ? -61.620  18.798   -43.196 1.00 34.84  ? 194  ILE E C     1 
ATOM   14709 O O     . ILE E 1 194 ? -62.527  18.946   -44.023 1.00 36.13  ? 194  ILE E O     1 
ATOM   14710 C CB    . ILE E 1 194 ? -60.901  21.207   -42.904 1.00 34.87  ? 194  ILE E CB    1 
ATOM   14711 C CG1   . ILE E 1 194 ? -59.710  22.188   -42.760 1.00 37.28  ? 194  ILE E CG1   1 
ATOM   14712 C CG2   . ILE E 1 194 ? -61.867  21.288   -41.712 1.00 28.71  ? 194  ILE E CG2   1 
ATOM   14713 C CD1   . ILE E 1 194 ? -60.141  23.646   -42.561 1.00 31.97  ? 194  ILE E CD1   1 
ATOM   14714 N N     . VAL E 1 195 ? -61.629  17.865   -42.263 1.00 32.78  ? 195  VAL E N     1 
ATOM   14715 C CA    . VAL E 1 195 ? -62.670  16.882   -42.148 1.00 32.74  ? 195  VAL E CA    1 
ATOM   14716 C C     . VAL E 1 195 ? -63.484  17.098   -40.891 1.00 35.07  ? 195  VAL E C     1 
ATOM   14717 O O     . VAL E 1 195 ? -62.949  17.345   -39.854 1.00 36.06  ? 195  VAL E O     1 
ATOM   14718 C CB    . VAL E 1 195 ? -62.084  15.488   -42.083 1.00 31.55  ? 195  VAL E CB    1 
ATOM   14719 C CG1   . VAL E 1 195 ? -63.165  14.453   -42.144 1.00 33.43  ? 195  VAL E CG1   1 
ATOM   14720 C CG2   . VAL E 1 195 ? -61.096  15.284   -43.185 1.00 30.69  ? 195  VAL E CG2   1 
ATOM   14721 N N     . SER E 1 196 ? -64.789  17.026   -41.010 1.00 30.06  ? 196  SER E N     1 
ATOM   14722 C CA    . SER E 1 196 ? -65.638  17.188   -39.878 1.00 35.20  ? 196  SER E CA    1 
ATOM   14723 C C     . SER E 1 196 ? -66.582  16.032   -39.662 1.00 37.58  ? 196  SER E C     1 
ATOM   14724 O O     . SER E 1 196 ? -67.251  15.619   -40.545 1.00 39.13  ? 196  SER E O     1 
ATOM   14725 C CB    . SER E 1 196 ? -66.441  18.455   -40.018 1.00 38.58  ? 196  SER E CB    1 
ATOM   14726 O OG    . SER E 1 196 ? -67.202  18.646   -38.883 1.00 41.43  ? 196  SER E OG    1 
ATOM   14727 N N     . ASN E 1 197 ? -66.635  15.544   -38.448 1.00 38.16  ? 197  ASN E N     1 
ATOM   14728 C CA    . ASN E 1 197 ? -67.488  14.458   -38.074 1.00 49.90  ? 197  ASN E CA    1 
ATOM   14729 C C     . ASN E 1 197 ? -68.908  14.947   -37.898 1.00 55.08  ? 197  ASN E C     1 
ATOM   14730 O O     . ASN E 1 197 ? -69.834  14.381   -38.388 1.00 75.69  ? 197  ASN E O     1 
ATOM   14731 C CB    . ASN E 1 197 ? -66.974  13.876   -36.781 1.00 52.31  ? 197  ASN E CB    1 
ATOM   14732 C CG    . ASN E 1 197 ? -67.318  12.433   -36.613 1.00 59.71  ? 197  ASN E CG    1 
ATOM   14733 O OD1   . ASN E 1 197 ? -67.686  11.754   -37.549 1.00 53.71  ? 197  ASN E OD1   1 
ATOM   14734 N ND2   . ASN E 1 197 ? -67.185  11.953   -35.407 1.00 55.66  ? 197  ASN E ND2   1 
ATOM   14735 N N     . THR E 1 198 ? -69.090  16.050   -37.234 1.00 78.92  ? 198  THR E N     1 
ATOM   14736 C CA    . THR E 1 198 ? -70.427  16.584   -37.062 1.00 87.86  ? 198  THR E CA    1 
ATOM   14737 C C     . THR E 1 198 ? -71.126  16.906   -38.371 1.00 78.87  ? 198  THR E C     1 
ATOM   14738 O O     . THR E 1 198 ? -70.523  17.323   -39.339 1.00 69.50  ? 198  THR E O     1 
ATOM   14739 C CB    . THR E 1 198 ? -70.413  17.842   -36.199 1.00 94.73  ? 198  THR E CB    1 
ATOM   14740 O OG1   . THR E 1 198 ? -71.715  18.073   -35.687 1.00 105.52 ? 198  THR E OG1   1 
ATOM   14741 C CG2   . THR E 1 198 ? -70.029  19.009   -37.005 1.00 90.08  ? 198  THR E CG2   1 
ATOM   14742 N N     . VAL E 1 206 ? -73.896  22.047   -45.082 1.00 68.66  ? 206  VAL E N     1 
ATOM   14743 C CA    . VAL E 1 206 ? -72.527  21.859   -44.506 1.00 80.72  ? 206  VAL E CA    1 
ATOM   14744 C C     . VAL E 1 206 ? -72.247  22.973   -43.495 1.00 75.86  ? 206  VAL E C     1 
ATOM   14745 O O     . VAL E 1 206 ? -72.720  24.097   -43.631 1.00 69.96  ? 206  VAL E O     1 
ATOM   14746 C CB    . VAL E 1 206 ? -71.433  21.782   -45.591 1.00 77.26  ? 206  VAL E CB    1 
ATOM   14747 C CG1   . VAL E 1 206 ? -71.311  23.084   -46.382 1.00 67.31  ? 206  VAL E CG1   1 
ATOM   14748 C CG2   . VAL E 1 206 ? -70.091  21.308   -45.025 1.00 61.43  ? 206  VAL E CG2   1 
ATOM   14749 N N     . SER E 1 207 ? -71.463  22.657   -42.469 1.00 81.83  ? 207  SER E N     1 
ATOM   14750 C CA    . SER E 1 207 ? -71.444  23.519   -41.288 1.00 76.68  ? 207  SER E CA    1 
ATOM   14751 C C     . SER E 1 207 ? -70.526  24.738   -41.453 1.00 66.69  ? 207  SER E C     1 
ATOM   14752 O O     . SER E 1 207 ? -70.584  25.651   -40.629 1.00 62.41  ? 207  SER E O     1 
ATOM   14753 C CB    . SER E 1 207 ? -71.171  22.745   -40.016 1.00 67.41  ? 207  SER E CB    1 
ATOM   14754 O OG    . SER E 1 207 ? -69.812  22.350   -39.989 1.00 75.74  ? 207  SER E OG    1 
ATOM   14755 N N     . ASP E 1 208 ? -69.689  24.757   -42.502 1.00 49.35  ? 208  ASP E N     1 
ATOM   14756 C CA    . ASP E 1 208 ? -68.817  25.882   -42.780 1.00 42.96  ? 208  ASP E CA    1 
ATOM   14757 C C     . ASP E 1 208 ? -68.207  25.717   -44.172 1.00 47.07  ? 208  ASP E C     1 
ATOM   14758 O O     . ASP E 1 208 ? -67.784  24.625   -44.546 1.00 55.66  ? 208  ASP E O     1 
ATOM   14759 C CB    . ASP E 1 208 ? -67.665  26.002   -41.789 1.00 47.52  ? 208  ASP E CB    1 
ATOM   14760 C CG    . ASP E 1 208 ? -66.893  27.316   -41.900 1.00 50.90  ? 208  ASP E CG    1 
ATOM   14761 O OD1   . ASP E 1 208 ? -67.313  28.305   -41.248 1.00 50.72  ? 208  ASP E OD1   1 
ATOM   14762 O OD2   . ASP E 1 208 ? -65.929  27.377   -42.699 1.00 40.68  ? 208  ASP E OD2   1 
ATOM   14763 N N     . PRO E 1 209 ? -68.102  26.805   -44.974 1.00 52.48  ? 209  PRO E N     1 
ATOM   14764 C CA    . PRO E 1 209 ? -67.540  26.713   -46.324 1.00 46.72  ? 209  PRO E CA    1 
ATOM   14765 C C     . PRO E 1 209 ? -66.135  26.098   -46.389 1.00 46.53  ? 209  PRO E C     1 
ATOM   14766 O O     . PRO E 1 209 ? -65.743  25.552   -47.420 1.00 45.95  ? 209  PRO E O     1 
ATOM   14767 C CB    . PRO E 1 209 ? -67.593  28.147   -46.863 1.00 44.88  ? 209  PRO E CB    1 
ATOM   14768 C CG    . PRO E 1 209 ? -68.699  28.772   -46.015 1.00 49.03  ? 209  PRO E CG    1 
ATOM   14769 C CD    . PRO E 1 209 ? -68.568  28.166   -44.641 1.00 51.07  ? 209  PRO E CD    1 
ATOM   14770 N N     . GLU E 1 210 ? -65.370  26.173   -45.294 1.00 43.40  ? 210  GLU E N     1 
ATOM   14771 C CA    . GLU E 1 210 ? -63.984  25.722   -45.335 1.00 41.58  ? 210  GLU E CA    1 
ATOM   14772 C C     . GLU E 1 210 ? -63.846  24.198   -45.169 1.00 42.21  ? 210  GLU E C     1 
ATOM   14773 O O     . GLU E 1 210 ? -62.758  23.657   -45.412 1.00 35.11  ? 210  GLU E O     1 
ATOM   14774 C CB    . GLU E 1 210 ? -63.106  26.466   -44.322 1.00 42.23  ? 210  GLU E CB    1 
ATOM   14775 C CG    . GLU E 1 210 ? -62.778  27.885   -44.764 1.00 45.72  ? 210  GLU E CG    1 
ATOM   14776 C CD    . GLU E 1 210 ? -62.056  27.975   -46.106 1.00 54.94  ? 210  GLU E CD    1 
ATOM   14777 O OE1   . GLU E 1 210 ? -61.459  27.007   -46.630 1.00 57.41  ? 210  GLU E OE1   1 
ATOM   14778 O OE2   . GLU E 1 210 ? -62.117  29.073   -46.679 1.00 60.91  ? 210  GLU E OE2   1 
ATOM   14779 N N     . ILE E 1 211 ? -64.920  23.510   -44.732 1.00 35.71  ? 211  ILE E N     1 
ATOM   14780 C CA    . ILE E 1 211 ? -64.906  22.054   -44.644 1.00 38.31  ? 211  ILE E CA    1 
ATOM   14781 C C     . ILE E 1 211 ? -64.706  21.433   -46.029 1.00 34.24  ? 211  ILE E C     1 
ATOM   14782 O O     . ILE E 1 211 ? -65.340  21.846   -46.987 1.00 34.80  ? 211  ILE E O     1 
ATOM   14783 C CB    . ILE E 1 211 ? -66.196  21.554   -43.966 1.00 40.31  ? 211  ILE E CB    1 
ATOM   14784 C CG1   . ILE E 1 211 ? -66.095  21.735   -42.454 1.00 35.99  ? 211  ILE E CG1   1 
ATOM   14785 C CG2   . ILE E 1 211 ? -66.473  20.094   -44.334 1.00 40.15  ? 211  ILE E CG2   1 
ATOM   14786 C CD1   . ILE E 1 211 ? -67.440  21.834   -41.790 1.00 34.28  ? 211  ILE E CD1   1 
ATOM   14787 N N     . ASP E 1 212 ? -63.827  20.425   -46.120 1.00 36.98  ? 212  ASP E N     1 
ATOM   14788 C CA    . ASP E 1 212 ? -63.492  19.742   -47.364 1.00 34.12  ? 212  ASP E CA    1 
ATOM   14789 C C     . ASP E 1 212 ? -64.137  18.349   -47.460 1.00 35.01  ? 212  ASP E C     1 
ATOM   14790 O O     . ASP E 1 212 ? -64.370  17.841   -48.567 1.00 36.95  ? 212  ASP E O     1 
ATOM   14791 C CB    . ASP E 1 212 ? -61.991  19.616   -47.484 1.00 36.97  ? 212  ASP E CB    1 
ATOM   14792 C CG    . ASP E 1 212 ? -61.234  20.933   -47.543 1.00 40.16  ? 212  ASP E CG    1 
ATOM   14793 O OD1   . ASP E 1 212 ? -61.753  21.886   -48.179 1.00 36.91  ? 212  ASP E OD1   1 
ATOM   14794 O OD2   . ASP E 1 212 ? -60.095  20.976   -47.014 1.00 37.58  ? 212  ASP E OD2   1 
ATOM   14795 N N     . VAL E 1 213 ? -64.360  17.704   -46.301 1.00 31.14  ? 213  VAL E N     1 
ATOM   14796 C CA    . VAL E 1 213 ? -64.800  16.319   -46.246 1.00 31.09  ? 213  VAL E CA    1 
ATOM   14797 C C     . VAL E 1 213 ? -65.781  16.183   -45.086 1.00 33.05  ? 213  VAL E C     1 
ATOM   14798 O O     . VAL E 1 213 ? -65.525  16.673   -43.982 1.00 32.91  ? 213  VAL E O     1 
ATOM   14799 C CB    . VAL E 1 213 ? -63.646  15.323   -46.039 1.00 30.25  ? 213  VAL E CB    1 
ATOM   14800 C CG1   . VAL E 1 213 ? -64.174  13.875   -45.983 1.00 26.96  ? 213  VAL E CG1   1 
ATOM   14801 C CG2   . VAL E 1 213 ? -62.522  15.501   -47.064 1.00 24.49  ? 213  VAL E CG2   1 
ATOM   14802 N N     . VAL E 1 214 ? -66.814  15.414   -45.323 1.00 32.92  ? 214  VAL E N     1 
ATOM   14803 C CA    . VAL E 1 214 ? -67.838  15.124   -44.359 1.00 37.38  ? 214  VAL E CA    1 
ATOM   14804 C C     . VAL E 1 214 ? -67.866  13.606   -44.122 1.00 35.20  ? 214  VAL E C     1 
ATOM   14805 O O     . VAL E 1 214 ? -67.596  12.862   -44.996 1.00 30.04  ? 214  VAL E O     1 
ATOM   14806 C CB    . VAL E 1 214 ? -69.177  15.651   -44.872 1.00 37.14  ? 214  VAL E CB    1 
ATOM   14807 C CG1   . VAL E 1 214 ? -70.316  15.296   -43.981 1.00 40.72  ? 214  VAL E CG1   1 
ATOM   14808 C CG2   . VAL E 1 214 ? -69.126  17.143   -44.957 1.00 40.85  ? 214  VAL E CG2   1 
ATOM   14809 N N     . THR E 1 215 ? -68.125  13.180   -42.903 1.00 35.60  ? 215  THR E N     1 
ATOM   14810 C CA    . THR E 1 215 ? -68.238  11.769   -42.569 1.00 42.73  ? 215  THR E CA    1 
ATOM   14811 C C     . THR E 1 215 ? -69.641  11.189   -42.695 1.00 42.57  ? 215  THR E C     1 
ATOM   14812 O O     . THR E 1 215 ? -70.611  11.839   -42.461 1.00 43.59  ? 215  THR E O     1 
ATOM   14813 C CB    . THR E 1 215 ? -67.715  11.483   -41.190 1.00 37.87  ? 215  THR E CB    1 
ATOM   14814 O OG1   . THR E 1 215 ? -68.425  12.273   -40.268 1.00 33.92  ? 215  THR E OG1   1 
ATOM   14815 C CG2   . THR E 1 215 ? -66.290  11.812   -41.122 1.00 36.35  ? 215  THR E CG2   1 
ATOM   14816 N N     . TYR E 1 216 ? -69.714  9.937    -43.076 1.00 45.38  ? 216  TYR E N     1 
ATOM   14817 C CA    . TYR E 1 216 ? -70.966  9.264    -43.269 1.00 47.13  ? 216  TYR E CA    1 
ATOM   14818 C C     . TYR E 1 216 ? -70.944  7.920    -42.606 1.00 54.25  ? 216  TYR E C     1 
ATOM   14819 O O     . TYR E 1 216 ? -69.899  7.392    -42.316 1.00 53.69  ? 216  TYR E O     1 
ATOM   14820 C CB    . TYR E 1 216 ? -71.229  9.070    -44.752 1.00 42.06  ? 216  TYR E CB    1 
ATOM   14821 C CG    . TYR E 1 216 ? -71.427  10.328   -45.522 1.00 51.67  ? 216  TYR E CG    1 
ATOM   14822 C CD1   . TYR E 1 216 ? -70.376  10.997   -46.079 1.00 48.54  ? 216  TYR E CD1   1 
ATOM   14823 C CD2   . TYR E 1 216 ? -72.675  10.847   -45.700 1.00 63.38  ? 216  TYR E CD2   1 
ATOM   14824 C CE1   . TYR E 1 216 ? -70.566  12.153   -46.785 1.00 48.32  ? 216  TYR E CE1   1 
ATOM   14825 C CE2   . TYR E 1 216 ? -72.874  12.000   -46.408 1.00 63.18  ? 216  TYR E CE2   1 
ATOM   14826 C CZ    . TYR E 1 216 ? -71.814  12.644   -46.943 1.00 58.68  ? 216  TYR E CZ    1 
ATOM   14827 O OH    . TYR E 1 216 ? -72.036  13.771   -47.646 1.00 56.29  ? 216  TYR E OH    1 
ATOM   14828 N N     . GLU E 1 217 ? -72.124  7.404    -42.321 1.00 59.20  ? 217  GLU E N     1 
ATOM   14829 C CA    . GLU E 1 217 ? -72.284  6.101    -41.732 1.00 59.16  ? 217  GLU E CA    1 
ATOM   14830 C C     . GLU E 1 217 ? -71.861  5.066    -42.734 1.00 53.07  ? 217  GLU E C     1 
ATOM   14831 O O     . GLU E 1 217 ? -72.143  5.180    -43.893 1.00 53.05  ? 217  GLU E O     1 
ATOM   14832 C CB    . GLU E 1 217 ? -73.715  5.893    -41.313 1.00 75.93  ? 217  GLU E CB    1 
ATOM   14833 C CG    . GLU E 1 217 ? -74.020  6.555    -39.996 1.00 98.38  ? 217  GLU E CG    1 
ATOM   14834 C CD    . GLU E 1 217 ? -74.975  5.761    -39.147 1.00 119.59 ? 217  GLU E CD    1 
ATOM   14835 O OE1   . GLU E 1 217 ? -76.078  5.448    -39.642 1.00 119.10 ? 217  GLU E OE1   1 
ATOM   14836 O OE2   . GLU E 1 217 ? -74.618  5.459    -37.983 1.00 112.75 ? 217  GLU E OE2   1 
ATOM   14837 N N     . ARG E 1 218 ? -71.230  4.022    -42.261 1.00 48.09  ? 218  ARG E N     1 
ATOM   14838 C CA    . ARG E 1 218 ? -70.693  3.045    -43.157 1.00 50.65  ? 218  ARG E CA    1 
ATOM   14839 C C     . ARG E 1 218 ? -71.709  2.310    -43.973 1.00 45.00  ? 218  ARG E C     1 
ATOM   14840 O O     . ARG E 1 218 ? -71.415  1.837    -45.015 1.00 45.94  ? 218  ARG E O     1 
ATOM   14841 C CB    . ARG E 1 218 ? -69.678  2.132    -42.475 1.00 53.53  ? 218  ARG E CB    1 
ATOM   14842 C CG    . ARG E 1 218 ? -70.207  1.114    -41.514 1.00 49.65  ? 218  ARG E CG    1 
ATOM   14843 C CD    . ARG E 1 218 ? -69.093  0.577    -40.659 1.00 58.36  ? 218  ARG E CD    1 
ATOM   14844 N NE    . ARG E 1 218 ? -69.466  -0.701   -40.095 1.00 66.01  ? 218  ARG E NE    1 
ATOM   14845 C CZ    . ARG E 1 218 ? -70.094  -0.859   -38.953 1.00 65.39  ? 218  ARG E CZ    1 
ATOM   14846 N NH1   . ARG E 1 218 ? -70.406  -2.063   -38.564 1.00 68.58  ? 218  ARG E NH1   1 
ATOM   14847 N NH2   . ARG E 1 218 ? -70.432  0.175    -38.212 1.00 58.06  ? 218  ARG E NH2   1 
ATOM   14848 N N     . ARG E 1 219 ? -72.918  2.236    -43.484 1.00 54.96  ? 219  ARG E N     1 
ATOM   14849 C CA    . ARG E 1 219 ? -73.972  1.500    -44.162 1.00 62.43  ? 219  ARG E CA    1 
ATOM   14850 C C     . ARG E 1 219 ? -74.703  2.373    -45.186 1.00 61.64  ? 219  ARG E C     1 
ATOM   14851 O O     . ARG E 1 219 ? -75.641  1.876    -45.800 1.00 60.90  ? 219  ARG E O     1 
ATOM   14852 C CB    . ARG E 1 219 ? -74.905  0.833    -43.141 1.00 67.23  ? 219  ARG E CB    1 
ATOM   14853 C CG    . ARG E 1 219 ? -74.255  -0.386   -42.496 1.00 73.15  ? 219  ARG E CG    1 
ATOM   14854 C CD    . ARG E 1 219 ? -75.112  -0.921   -41.364 1.00 82.98  ? 219  ARG E CD    1 
ATOM   14855 N NE    . ARG E 1 219 ? -74.730  -2.259   -40.903 1.00 88.64  ? 219  ARG E NE    1 
ATOM   14856 C CZ    . ARG E 1 219 ? -74.405  -2.538   -39.640 1.00 102.66 ? 219  ARG E CZ    1 
ATOM   14857 N NH1   . ARG E 1 219 ? -74.188  -3.794   -39.274 1.00 87.16  ? 219  ARG E NH1   1 
ATOM   14858 N NH2   . ARG E 1 219 ? -74.284  -1.547   -38.759 1.00 94.08  ? 219  ARG E NH2   1 
ATOM   14859 N N     . THR E 1 220 ? -74.288  3.641    -45.389 1.00 53.11  ? 220  THR E N     1 
ATOM   14860 C CA    . THR E 1 220 ? -74.947  4.494    -46.374 1.00 58.93  ? 220  THR E CA    1 
ATOM   14861 C C     . THR E 1 220 ? -75.133  3.696    -47.671 1.00 58.14  ? 220  THR E C     1 
ATOM   14862 O O     . THR E 1 220 ? -74.153  3.225    -48.248 1.00 45.88  ? 220  THR E O     1 
ATOM   14863 C CB    . THR E 1 220 ? -74.162  5.780    -46.639 1.00 55.75  ? 220  THR E CB    1 
ATOM   14864 O OG1   . THR E 1 220 ? -73.913  6.412    -45.385 1.00 56.89  ? 220  THR E OG1   1 
ATOM   14865 C CG2   . THR E 1 220 ? -74.915  6.720    -47.569 1.00 49.80  ? 220  THR E CG2   1 
ATOM   14866 N N     . PRO E 1 221 ? -76.383  3.516    -48.182 1.00 62.24  ? 221  PRO E N     1 
ATOM   14867 C CA    . PRO E 1 221 ? -76.601  2.643    -49.342 1.00 59.83  ? 221  PRO E CA    1 
ATOM   14868 C C     . PRO E 1 221 ? -76.165  3.241    -50.686 1.00 63.00  ? 221  PRO E C     1 
ATOM   14869 O O     . PRO E 1 221 ? -75.690  2.510    -51.555 1.00 55.59  ? 221  PRO E O     1 
ATOM   14870 C CB    . PRO E 1 221 ? -78.083  2.233    -49.246 1.00 55.06  ? 221  PRO E CB    1 
ATOM   14871 C CG    . PRO E 1 221 ? -78.713  3.345    -48.396 1.00 56.64  ? 221  PRO E CG    1 
ATOM   14872 C CD    . PRO E 1 221 ? -77.633  4.112    -47.657 1.00 58.03  ? 221  PRO E CD    1 
ATOM   14873 N N     . ASP E 1 222 ? -76.309  4.570    -50.847 1.00 67.55  ? 222  ASP E N     1 
ATOM   14874 C CA    . ASP E 1 222 ? -76.170  5.200    -52.155 1.00 69.16  ? 222  ASP E CA    1 
ATOM   14875 C C     . ASP E 1 222 ? -74.992  6.164    -52.167 1.00 65.08  ? 222  ASP E C     1 
ATOM   14876 O O     . ASP E 1 222 ? -74.549  6.605    -51.102 1.00 70.57  ? 222  ASP E O     1 
ATOM   14877 C CB    . ASP E 1 222 ? -77.393  6.021    -52.536 1.00 89.79  ? 222  ASP E CB    1 
ATOM   14878 C CG    . ASP E 1 222 ? -78.731  5.293    -52.447 1.00 99.46  ? 222  ASP E CG    1 
ATOM   14879 O OD1   . ASP E 1 222 ? -78.913  4.281    -53.177 1.00 90.70  ? 222  ASP E OD1   1 
ATOM   14880 O OD2   . ASP E 1 222 ? -79.575  5.730    -51.627 1.00 93.72  ? 222  ASP E OD2   1 
ATOM   14881 N N     . GLU E 1 223 ? -74.551  6.510    -53.390 1.00 52.84  ? 223  GLU E N     1 
ATOM   14882 C CA    . GLU E 1 223 ? -73.508  7.505    -53.622 1.00 62.72  ? 223  GLU E CA    1 
ATOM   14883 C C     . GLU E 1 223 ? -73.729  8.746    -52.747 1.00 62.52  ? 223  GLU E C     1 
ATOM   14884 O O     . GLU E 1 223 ? -74.856  9.226    -52.629 1.00 62.72  ? 223  GLU E O     1 
ATOM   14885 C CB    . GLU E 1 223 ? -73.440  7.795    -55.120 1.00 63.82  ? 223  GLU E CB    1 
ATOM   14886 C CG    . GLU E 1 223 ? -72.329  8.787    -55.458 1.00 81.41  ? 223  GLU E CG    1 
ATOM   14887 C CD    . GLU E 1 223 ? -72.051  8.960    -56.944 1.00 82.11  ? 223  GLU E CD    1 
ATOM   14888 O OE1   . GLU E 1 223 ? -72.745  8.309    -57.763 1.00 69.56  ? 223  GLU E OE1   1 
ATOM   14889 O OE2   . GLU E 1 223 ? -71.118  9.736    -57.270 1.00 69.15  ? 223  GLU E OE2   1 
ATOM   14890 N N     . ILE E 1 224 ? -72.656  9.251    -52.122 1.00 62.75  ? 224  ILE E N     1 
ATOM   14891 C CA    . ILE E 1 224 ? -72.777  10.274   -51.086 1.00 64.10  ? 224  ILE E CA    1 
ATOM   14892 C C     . ILE E 1 224 ? -73.058  11.641   -51.729 1.00 65.18  ? 224  ILE E C     1 
ATOM   14893 O O     . ILE E 1 224 ? -72.914  11.820   -52.949 1.00 53.40  ? 224  ILE E O     1 
ATOM   14894 C CB    . ILE E 1 224 ? -71.509  10.332   -50.211 1.00 56.20  ? 224  ILE E CB    1 
ATOM   14895 C CG1   . ILE E 1 224 ? -70.314  10.610   -51.084 1.00 58.51  ? 224  ILE E CG1   1 
ATOM   14896 C CG2   . ILE E 1 224 ? -71.302  9.071    -49.383 1.00 45.53  ? 224  ILE E CG2   1 
ATOM   14897 C CD1   . ILE E 1 224 ? -69.271  11.467   -50.402 1.00 59.93  ? 224  ILE E CD1   1 
ATOM   14898 N N     . TYR E 1 225 ? -73.407  12.612   -50.864 1.00 74.20  ? 225  TYR E N     1 
ATOM   14899 C CA    . TYR E 1 225 ? -73.744  13.971   -51.265 1.00 89.20  ? 225  TYR E CA    1 
ATOM   14900 C C     . TYR E 1 225 ? -72.493  14.850   -51.392 1.00 68.89  ? 225  TYR E C     1 
ATOM   14901 O O     . TYR E 1 225 ? -71.673  14.907   -50.479 1.00 62.97  ? 225  TYR E O     1 
ATOM   14902 C CB    . TYR E 1 225 ? -74.682  14.457   -50.152 1.00 104.22 ? 225  TYR E CB    1 
ATOM   14903 C CG    . TYR E 1 225 ? -75.044  15.935   -50.228 1.00 131.70 ? 225  TYR E CG    1 
ATOM   14904 C CD1   . TYR E 1 225 ? -75.797  16.426   -51.298 1.00 139.28 ? 225  TYR E CD1   1 
ATOM   14905 C CD2   . TYR E 1 225 ? -74.640  16.832   -49.235 1.00 118.31 ? 225  TYR E CD2   1 
ATOM   14906 C CE1   . TYR E 1 225 ? -76.122  17.774   -51.390 1.00 145.88 ? 225  TYR E CE1   1 
ATOM   14907 C CE2   . TYR E 1 225 ? -74.970  18.178   -49.310 1.00 125.57 ? 225  TYR E CE2   1 
ATOM   14908 C CZ    . TYR E 1 225 ? -75.713  18.644   -50.388 1.00 148.52 ? 225  TYR E CZ    1 
ATOM   14909 O OH    . TYR E 1 225 ? -76.031  19.968   -50.456 1.00 150.55 ? 225  TYR E OH    1 
ATOM   14910 N N     . HIS E 1 226 ? -72.374  15.595   -52.496 1.00 63.34  ? 226  HIS E N     1 
ATOM   14911 C CA    . HIS E 1 226 ? -71.161  16.377   -52.724 1.00 64.95  ? 226  HIS E CA    1 
ATOM   14912 C C     . HIS E 1 226 ? -71.333  17.898   -52.559 1.00 59.57  ? 226  HIS E C     1 
ATOM   14913 O O     . HIS E 1 226 ? -70.395  18.634   -52.839 1.00 47.84  ? 226  HIS E O     1 
ATOM   14914 C CB    . HIS E 1 226 ? -70.538  15.992   -54.069 1.00 61.10  ? 226  HIS E CB    1 
ATOM   14915 C CG    . HIS E 1 226 ? -70.024  14.602   -54.064 1.00 67.23  ? 226  HIS E CG    1 
ATOM   14916 N ND1   . HIS E 1 226 ? -69.087  14.172   -53.143 1.00 65.80  ? 226  HIS E ND1   1 
ATOM   14917 C CD2   . HIS E 1 226 ? -70.273  13.558   -54.864 1.00 63.35  ? 226  HIS E CD2   1 
ATOM   14918 C CE1   . HIS E 1 226 ? -68.798  12.897   -53.370 1.00 63.97  ? 226  HIS E CE1   1 
ATOM   14919 N NE2   . HIS E 1 226 ? -69.511  12.504   -54.407 1.00 67.29  ? 226  HIS E NE2   1 
ATOM   14920 N N     . GLY E 1 227 ? -72.500  18.369   -52.088 1.00 77.12  ? 227  GLY E N     1 
ATOM   14921 C CA    . GLY E 1 227 ? -72.824  19.792   -51.996 1.00 90.24  ? 227  GLY E CA    1 
ATOM   14922 C C     . GLY E 1 227 ? -73.873  20.242   -53.026 1.00 105.19 ? 227  GLY E C     1 
ATOM   14923 O O     . GLY E 1 227 ? -74.080  19.563   -54.034 1.00 92.23  ? 227  GLY E O     1 
ATOM   14924 N N     . ALA E 1 228 ? -74.528  21.393   -52.769 1.00 113.82 ? 228  ALA E N     1 
ATOM   14925 C CA    . ALA E 1 228 ? -75.513  21.977   -53.676 1.00 107.90 ? 228  ALA E CA    1 
ATOM   14926 C C     . ALA E 1 228 ? -74.828  22.388   -54.983 1.00 108.94 ? 228  ALA E C     1 
ATOM   14927 O O     . ALA E 1 228 ? -73.642  22.711   -54.970 1.00 116.09 ? 228  ALA E O     1 
ATOM   14928 C CB    . ALA E 1 228 ? -76.210  23.145   -53.015 1.00 102.56 ? 228  ALA E CB    1 
ATOM   14929 N N     . PRO E 1 229 ? -75.519  22.391   -56.154 1.00 119.72 ? 229  PRO E N     1 
ATOM   14930 C CA    . PRO E 1 229 ? -74.885  22.840   -57.394 1.00 123.35 ? 229  PRO E CA    1 
ATOM   14931 C C     . PRO E 1 229 ? -74.518  24.331   -57.366 1.00 126.93 ? 229  PRO E C     1 
ATOM   14932 O O     . PRO E 1 229 ? -75.197  25.150   -56.742 1.00 109.01 ? 229  PRO E O     1 
ATOM   14933 C CB    . PRO E 1 229 ? -75.803  22.339   -58.514 1.00 108.85 ? 229  PRO E CB    1 
ATOM   14934 C CG    . PRO E 1 229 ? -77.123  22.026   -57.825 1.00 116.13 ? 229  PRO E CG    1 
ATOM   14935 C CD    . PRO E 1 229 ? -76.938  22.023   -56.331 1.00 121.47 ? 229  PRO E CD    1 
ATOM   14936 N N     . ASN E 1 230 ? -73.386  24.677   -57.991 1.00 111.25 ? 230  ASN E N     1 
ATOM   14937 C CA    . ASN E 1 230 ? -72.809  26.009   -57.894 1.00 101.99 ? 230  ASN E CA    1 
ATOM   14938 C C     . ASN E 1 230 ? -72.056  26.225   -56.581 1.00 92.57  ? 230  ASN E C     1 
ATOM   14939 O O     . ASN E 1 230 ? -71.431  27.276   -56.440 1.00 99.03  ? 230  ASN E O     1 
ATOM   14940 C CB    . ASN E 1 230 ? -73.792  27.133   -58.221 1.00 99.86  ? 230  ASN E CB    1 
ATOM   14941 C CG    . ASN E 1 230 ? -73.855  27.420   -59.702 1.00 98.39  ? 230  ASN E CG    1 
ATOM   14942 O OD1   . ASN E 1 230 ? -73.369  26.643   -60.532 1.00 96.24  ? 230  ASN E OD1   1 
ATOM   14943 N ND2   . ASN E 1 230 ? -74.374  28.585   -60.053 1.00 92.58  ? 230  ASN E ND2   1 
ATOM   14944 N N     . GLU E 1 231 ? -72.068  25.247   -55.654 1.00 88.15  ? 231  GLU E N     1 
ATOM   14945 C CA    . GLU E 1 231 ? -71.307  25.380   -54.417 1.00 75.81  ? 231  GLU E CA    1 
ATOM   14946 C C     . GLU E 1 231 ? -70.043  24.514   -54.440 1.00 65.14  ? 231  GLU E C     1 
ATOM   14947 O O     . GLU E 1 231 ? -69.812  23.770   -55.385 1.00 65.21  ? 231  GLU E O     1 
ATOM   14948 C CB    . GLU E 1 231 ? -72.218  25.219   -53.208 1.00 82.57  ? 231  GLU E CB    1 
ATOM   14949 C CG    . GLU E 1 231 ? -73.334  26.257   -53.251 1.00 93.40  ? 231  GLU E CG    1 
ATOM   14950 C CD    . GLU E 1 231 ? -74.141  26.432   -52.000 1.00 100.79 ? 231  GLU E CD    1 
ATOM   14951 O OE1   . GLU E 1 231 ? -74.939  25.529   -51.681 1.00 106.34 ? 231  GLU E OE1   1 
ATOM   14952 O OE2   . GLU E 1 231 ? -73.976  27.486   -51.359 1.00 94.91  ? 231  GLU E OE2   1 
ATOM   14953 N N     . LYS E 1 232 ? -69.191  24.693   -53.421 1.00 59.64  ? 232  LYS E N     1 
ATOM   14954 C CA    . LYS E 1 232 ? -67.955  23.936   -53.292 1.00 52.65  ? 232  LYS E CA    1 
ATOM   14955 C C     . LYS E 1 232 ? -68.285  22.440   -53.209 1.00 45.76  ? 232  LYS E C     1 
ATOM   14956 O O     . LYS E 1 232 ? -69.189  22.028   -52.475 1.00 41.36  ? 232  LYS E O     1 
ATOM   14957 C CB    . LYS E 1 232 ? -67.277  24.382   -51.991 1.00 46.25  ? 232  LYS E CB    1 
ATOM   14958 C CG    . LYS E 1 232 ? -65.875  23.823   -51.783 1.00 45.28  ? 232  LYS E CG    1 
ATOM   14959 C CD    . LYS E 1 232 ? -65.527  23.849   -50.299 1.00 45.26  ? 232  LYS E CD    1 
ATOM   14960 C CE    . LYS E 1 232 ? -64.150  23.322   -50.028 1.00 41.74  ? 232  LYS E CE    1 
ATOM   14961 N NZ    . LYS E 1 232 ? -63.774  23.542   -48.625 1.00 43.95  ? 232  LYS E NZ    1 
ATOM   14962 N N     . TYR E 1 233 ? -67.566  21.637   -53.993 1.00 40.87  ? 233  TYR E N     1 
ATOM   14963 C CA    . TYR E 1 233 ? -67.649  20.189   -53.882 1.00 45.37  ? 233  TYR E CA    1 
ATOM   14964 C C     . TYR E 1 233 ? -66.993  19.707   -52.577 1.00 45.33  ? 233  TYR E C     1 
ATOM   14965 O O     . TYR E 1 233 ? -65.831  20.028   -52.288 1.00 39.83  ? 233  TYR E O     1 
ATOM   14966 C CB    . TYR E 1 233 ? -66.820  19.653   -55.047 1.00 41.20  ? 233  TYR E CB    1 
ATOM   14967 C CG    . TYR E 1 233 ? -66.765  18.130   -55.110 1.00 53.43  ? 233  TYR E CG    1 
ATOM   14968 C CD1   . TYR E 1 233 ? -65.855  17.406   -54.335 1.00 42.95  ? 233  TYR E CD1   1 
ATOM   14969 C CD2   . TYR E 1 233 ? -67.634  17.409   -55.951 1.00 52.62  ? 233  TYR E CD2   1 
ATOM   14970 C CE1   . TYR E 1 233 ? -65.782  16.021   -54.413 1.00 45.73  ? 233  TYR E CE1   1 
ATOM   14971 C CE2   . TYR E 1 233 ? -67.572  16.027   -56.031 1.00 48.45  ? 233  TYR E CE2   1 
ATOM   14972 C CZ    . TYR E 1 233 ? -66.642  15.335   -55.265 1.00 49.37  ? 233  TYR E CZ    1 
ATOM   14973 O OH    . TYR E 1 233 ? -66.569  13.980   -55.354 1.00 40.28  ? 233  TYR E OH    1 
ATOM   14974 N N     . VAL E 1 234 ? -67.733  18.894   -51.816 1.00 36.79  ? 234  VAL E N     1 
ATOM   14975 C CA    . VAL E 1 234 ? -67.239  18.314   -50.578 1.00 41.73  ? 234  VAL E CA    1 
ATOM   14976 C C     . VAL E 1 234 ? -67.144  16.795   -50.736 1.00 35.86  ? 234  VAL E C     1 
ATOM   14977 O O     . VAL E 1 234 ? -68.085  16.152   -51.193 1.00 36.95  ? 234  VAL E O     1 
ATOM   14978 C CB    . VAL E 1 234 ? -68.232  18.734   -49.477 1.00 44.36  ? 234  VAL E CB    1 
ATOM   14979 C CG1   . VAL E 1 234 ? -67.892  18.111   -48.134 1.00 43.40  ? 234  VAL E CG1   1 
ATOM   14980 C CG2   . VAL E 1 234 ? -68.230  20.253   -49.320 1.00 41.46  ? 234  VAL E CG2   1 
ATOM   14981 N N     . ALA E 1 235 ? -65.996  16.229   -50.363 1.00 32.89  ? 235  ALA E N     1 
ATOM   14982 C CA    . ALA E 1 235 ? -65.798  14.789   -50.411 1.00 33.38  ? 235  ALA E CA    1 
ATOM   14983 C C     . ALA E 1 235 ? -66.458  14.120   -49.196 1.00 31.44  ? 235  ALA E C     1 
ATOM   14984 O O     . ALA E 1 235 ? -67.000  14.797   -48.316 1.00 32.97  ? 235  ALA E O     1 
ATOM   14985 C CB    . ALA E 1 235 ? -64.320  14.485   -50.490 1.00 31.96  ? 235  ALA E CB    1 
ATOM   14986 N N     . GLY E 1 236 ? -66.408  12.782   -49.140 1.00 30.43  ? 236  GLY E N     1 
ATOM   14987 C CA    . GLY E 1 236 ? -67.006  12.024   -48.040 1.00 28.52  ? 236  GLY E CA    1 
ATOM   14988 C C     . GLY E 1 236 ? -66.093  10.889   -47.569 1.00 27.94  ? 236  GLY E C     1 
ATOM   14989 O O     . GLY E 1 236 ? -65.200  10.447   -48.295 1.00 31.99  ? 236  GLY E O     1 
ATOM   14990 N N     . GLU E 1 237 ? -66.312  10.420   -46.336 1.00 27.51  ? 237  GLU E N     1 
ATOM   14991 C CA    . GLU E 1 237 ? -65.454  9.395    -45.745 1.00 26.23  ? 237  GLU E CA    1 
ATOM   14992 C C     . GLU E 1 237 ? -66.293  8.547    -44.797 1.00 27.88  ? 237  GLU E C     1 
ATOM   14993 O O     . GLU E 1 237 ? -67.146  9.083    -44.092 1.00 29.12  ? 237  GLU E O     1 
ATOM   14994 C CB    . GLU E 1 237 ? -64.343  10.079   -44.951 1.00 24.03  ? 237  GLU E CB    1 
ATOM   14995 C CG    . GLU E 1 237 ? -63.206  9.159    -44.529 1.00 24.19  ? 237  GLU E CG    1 
ATOM   14996 C CD    . GLU E 1 237 ? -62.235  9.902    -43.597 1.00 34.67  ? 237  GLU E CD    1 
ATOM   14997 O OE1   . GLU E 1 237 ? -61.068  10.217   -43.989 1.00 33.73  ? 237  GLU E OE1   1 
ATOM   14998 O OE2   . GLU E 1 237 ? -62.649  10.173   -42.438 1.00 35.57  ? 237  GLU E OE2   1 
ATOM   14999 N N     . ILE E 1 238 ? -66.077  7.224    -44.817 1.00 28.08  ? 238  ILE E N     1 
ATOM   15000 C CA    . ILE E 1 238 ? -66.659  6.359    -43.804 1.00 27.54  ? 238  ILE E CA    1 
ATOM   15001 C C     . ILE E 1 238 ? -65.533  5.737    -42.973 1.00 27.68  ? 238  ILE E C     1 
ATOM   15002 O O     . ILE E 1 238 ? -64.373  5.737    -43.378 1.00 29.14  ? 238  ILE E O     1 
ATOM   15003 C CB    . ILE E 1 238 ? -67.619  5.318    -44.411 1.00 25.98  ? 238  ILE E CB    1 
ATOM   15004 C CG1   . ILE E 1 238 ? -66.888  4.276    -45.195 1.00 28.81  ? 238  ILE E CG1   1 
ATOM   15005 C CG2   . ILE E 1 238 ? -68.706  5.968    -45.273 1.00 26.76  ? 238  ILE E CG2   1 
ATOM   15006 C CD1   . ILE E 1 238 ? -67.826  3.264    -45.831 1.00 31.70  ? 238  ILE E CD1   1 
ATOM   15007 N N     . SER E 1 239 ? -65.902  5.189    -41.816 1.00 28.95  ? 239  SER E N     1 
ATOM   15008 C CA    . SER E 1 239 ? -64.997  4.649    -40.811 1.00 35.20  ? 239  SER E CA    1 
ATOM   15009 C C     . SER E 1 239 ? -65.462  3.265    -40.382 1.00 33.22  ? 239  SER E C     1 
ATOM   15010 O O     . SER E 1 239 ? -66.655  3.036    -40.264 1.00 33.75  ? 239  SER E O     1 
ATOM   15011 C CB    . SER E 1 239 ? -65.014  5.527    -39.589 1.00 36.06  ? 239  SER E CB    1 
ATOM   15012 O OG    . SER E 1 239 ? -64.101  6.580    -39.830 1.00 48.09  ? 239  SER E OG    1 
ATOM   15013 N N     . ILE E 1 240 ? -64.519  2.370    -40.091 1.00 30.05  ? 240  ILE E N     1 
ATOM   15014 C CA    . ILE E 1 240 ? -64.891  1.108    -39.491 1.00 27.04  ? 240  ILE E CA    1 
ATOM   15015 C C     . ILE E 1 240 ? -63.910  0.832    -38.365 1.00 28.43  ? 240  ILE E C     1 
ATOM   15016 O O     . ILE E 1 240 ? -62.695  1.012    -38.541 1.00 28.83  ? 240  ILE E O     1 
ATOM   15017 C CB    . ILE E 1 240 ? -64.962  -0.021   -40.547 1.00 26.92  ? 240  ILE E CB    1 
ATOM   15018 C CG1   . ILE E 1 240 ? -65.515  -1.314   -39.941 1.00 30.63  ? 240  ILE E CG1   1 
ATOM   15019 C CG2   . ILE E 1 240 ? -63.632  -0.272   -41.251 1.00 20.83  ? 240  ILE E CG2   1 
ATOM   15020 C CD1   . ILE E 1 240 ? -65.599  -2.468   -40.931 1.00 33.73  ? 240  ILE E CD1   1 
ATOM   15021 N N     . THR E 1 241 ? -64.436  0.410    -37.210 1.00 27.65  ? 241  THR E N     1 
ATOM   15022 C CA    . THR E 1 241 ? -63.545  -0.109   -36.184 1.00 28.27  ? 241  THR E CA    1 
ATOM   15023 C C     . THR E 1 241 ? -63.703  -1.636   -36.135 1.00 25.31  ? 241  THR E C     1 
ATOM   15024 O O     . THR E 1 241 ? -64.733  -2.167   -36.537 1.00 27.07  ? 241  THR E O     1 
ATOM   15025 C CB    . THR E 1 241 ? -63.817  0.604    -34.847 1.00 31.95  ? 241  THR E CB    1 
ATOM   15026 O OG1   . THR E 1 241 ? -62.691  0.256    -34.020 1.00 34.14  ? 241  THR E OG1   1 
ATOM   15027 C CG2   . THR E 1 241 ? -65.184  0.256    -34.267 1.00 22.80  ? 241  THR E CG2   1 
ATOM   15028 N N     . LEU E 1 242 ? -62.680  -2.351   -35.653 1.00 23.47  ? 242  LEU E N     1 
ATOM   15029 C CA    . LEU E 1 242 ? -62.645  -3.805   -35.769 1.00 23.67  ? 242  LEU E CA    1 
ATOM   15030 C C     . LEU E 1 242 ? -63.619  -4.487   -34.804 1.00 25.77  ? 242  LEU E C     1 
ATOM   15031 O O     . LEU E 1 242 ? -64.218  -5.504   -35.169 1.00 29.14  ? 242  LEU E O     1 
ATOM   15032 C CB    . LEU E 1 242 ? -61.230  -4.327   -35.579 1.00 24.63  ? 242  LEU E CB    1 
ATOM   15033 C CG    . LEU E 1 242 ? -60.197  -3.793   -36.589 1.00 28.27  ? 242  LEU E CG    1 
ATOM   15034 C CD1   . LEU E 1 242 ? -58.788  -4.351   -36.248 1.00 26.54  ? 242  LEU E CD1   1 
ATOM   15035 C CD2   . LEU E 1 242 ? -60.555  -4.032   -38.050 1.00 24.50  ? 242  LEU E CD2   1 
ATOM   15036 N N     . ASN E 1 243 ? -63.767  -3.953   -33.580 1.00 23.03  ? 243  ASN E N     1 
ATOM   15037 C CA    . ASN E 1 243 ? -64.768  -4.458   -32.658 1.00 21.96  ? 243  ASN E CA    1 
ATOM   15038 C C     . ASN E 1 243 ? -65.768  -3.339   -32.404 1.00 24.54  ? 243  ASN E C     1 
ATOM   15039 O O     . ASN E 1 243 ? -66.075  -2.584   -33.325 1.00 31.18  ? 243  ASN E O     1 
ATOM   15040 C CB    . ASN E 1 243 ? -64.137  -5.155   -31.448 1.00 23.43  ? 243  ASN E CB    1 
ATOM   15041 C CG    . ASN E 1 243 ? -63.188  -4.274   -30.681 1.00 26.95  ? 243  ASN E CG    1 
ATOM   15042 O OD1   . ASN E 1 243 ? -63.176  -3.059   -30.893 1.00 28.50  ? 243  ASN E OD1   1 
ATOM   15043 N ND2   . ASN E 1 243 ? -62.408  -4.838   -29.765 1.00 23.35  ? 243  ASN E ND2   1 
ATOM   15044 N N     . GLN E 1 244 ? -66.245  -3.195   -31.156 1.00 25.61  ? 244  GLN E N     1 
ATOM   15045 C CA    . GLN E 1 244 ? -67.264  -2.202   -30.859 1.00 25.22  ? 244  GLN E CA    1 
ATOM   15046 C C     . GLN E 1 244 ? -66.631  -0.886   -30.390 1.00 28.59  ? 244  GLN E C     1 
ATOM   15047 O O     . GLN E 1 244 ? -67.336  0.109    -30.285 1.00 30.94  ? 244  GLN E O     1 
ATOM   15048 C CB    . GLN E 1 244 ? -68.210  -2.745   -29.787 1.00 25.99  ? 244  GLN E CB    1 
ATOM   15049 C CG    . GLN E 1 244 ? -69.153  -3.855   -30.254 1.00 24.54  ? 244  GLN E CG    1 
ATOM   15050 C CD    . GLN E 1 244 ? -70.104  -3.341   -31.312 1.00 29.57  ? 244  GLN E CD    1 
ATOM   15051 O OE1   . GLN E 1 244 ? -70.918  -2.457   -31.051 1.00 35.34  ? 244  GLN E OE1   1 
ATOM   15052 N NE2   . GLN E 1 244 ? -69.957  -3.787   -32.548 1.00 27.59  ? 244  GLN E NE2   1 
ATOM   15053 N N     . HIS E 1 245 ? -65.313  -0.863   -30.141 1.00 25.04  ? 245  HIS E N     1 
ATOM   15054 C CA    . HIS E 1 245 ? -64.661  0.287    -29.513 1.00 25.86  ? 245  HIS E CA    1 
ATOM   15055 C C     . HIS E 1 245 ? -63.580  0.860    -30.434 1.00 26.39  ? 245  HIS E C     1 
ATOM   15056 O O     . HIS E 1 245 ? -63.047  0.159    -31.280 1.00 26.39  ? 245  HIS E O     1 
ATOM   15057 C CB    . HIS E 1 245 ? -64.103  -0.116   -28.142 1.00 22.89  ? 245  HIS E CB    1 
ATOM   15058 C CG    . HIS E 1 245 ? -65.192  -0.546   -27.213 1.00 27.26  ? 245  HIS E CG    1 
ATOM   15059 N ND1   . HIS E 1 245 ? -65.673  -1.837   -27.202 1.00 29.48  ? 245  HIS E ND1   1 
ATOM   15060 C CD2   . HIS E 1 245 ? -65.957  0.131    -26.315 1.00 28.79  ? 245  HIS E CD2   1 
ATOM   15061 C CE1   . HIS E 1 245 ? -66.630  -1.940   -26.278 1.00 31.18  ? 245  HIS E CE1   1 
ATOM   15062 N NE2   . HIS E 1 245 ? -66.836  -0.768   -25.738 1.00 29.49  ? 245  HIS E NE2   1 
ATOM   15063 N N     . TRP E 1 246 ? -63.241  2.133    -30.246 1.00 26.63  ? 246  TRP E N     1 
ATOM   15064 C CA    . TRP E 1 246 ? -62.198  2.788    -31.028 1.00 25.68  ? 246  TRP E CA    1 
ATOM   15065 C C     . TRP E 1 246 ? -60.838  2.673    -30.336 1.00 25.38  ? 246  TRP E C     1 
ATOM   15066 O O     . TRP E 1 246 ? -59.872  2.322    -30.980 1.00 26.59  ? 246  TRP E O     1 
ATOM   15067 C CB    . TRP E 1 246 ? -62.585  4.256    -31.293 1.00 27.98  ? 246  TRP E CB    1 
ATOM   15068 C CG    . TRP E 1 246 ? -63.848  4.292    -32.106 1.00 29.88  ? 246  TRP E CG    1 
ATOM   15069 C CD1   . TRP E 1 246 ? -65.116  4.204    -31.610 1.00 28.43  ? 246  TRP E CD1   1 
ATOM   15070 C CD2   . TRP E 1 246 ? -63.965  4.324    -33.549 1.00 28.02  ? 246  TRP E CD2   1 
ATOM   15071 N NE1   . TRP E 1 246 ? -66.013  4.172    -32.643 1.00 31.91  ? 246  TRP E NE1   1 
ATOM   15072 C CE2   . TRP E 1 246 ? -65.350  4.262    -33.841 1.00 31.93  ? 246  TRP E CE2   1 
ATOM   15073 C CE3   . TRP E 1 246 ? -63.056  4.437    -34.610 1.00 25.83  ? 246  TRP E CE3   1 
ATOM   15074 C CZ2   . TRP E 1 246 ? -65.846  4.296    -35.147 1.00 30.16  ? 246  TRP E CZ2   1 
ATOM   15075 C CZ3   . TRP E 1 246 ? -63.547  4.480    -35.900 1.00 27.32  ? 246  TRP E CZ3   1 
ATOM   15076 C CH2   . TRP E 1 246 ? -64.922  4.407    -36.162 1.00 29.53  ? 246  TRP E CH2   1 
ATOM   15077 N N     . GLY E 1 247 ? -60.752  3.018    -29.037 1.00 23.36  ? 247  GLY E N     1 
ATOM   15078 C CA    . GLY E 1 247 ? -59.558  2.683    -28.280 1.00 23.86  ? 247  GLY E CA    1 
ATOM   15079 C C     . GLY E 1 247 ? -59.553  1.171    -28.018 1.00 26.93  ? 247  GLY E C     1 
ATOM   15080 O O     . GLY E 1 247 ? -60.592  0.514    -28.156 1.00 25.74  ? 247  GLY E O     1 
ATOM   15081 N N     . ILE E 1 248 ? -58.408  0.637    -27.590 1.00 22.92  ? 248  ILE E N     1 
ATOM   15082 C CA    . ILE E 1 248 ? -58.285  -0.775   -27.293 1.00 24.85  ? 248  ILE E CA    1 
ATOM   15083 C C     . ILE E 1 248 ? -59.254  -1.165   -26.169 1.00 26.41  ? 248  ILE E C     1 
ATOM   15084 O O     . ILE E 1 248 ? -59.522  -0.393   -25.226 1.00 28.48  ? 248  ILE E O     1 
ATOM   15085 C CB    . ILE E 1 248 ? -56.814  -1.079   -26.952 1.00 25.57  ? 248  ILE E CB    1 
ATOM   15086 C CG1   . ILE E 1 248 ? -56.532  -2.574   -26.826 1.00 24.70  ? 248  ILE E CG1   1 
ATOM   15087 C CG2   . ILE E 1 248 ? -56.384  -0.320   -25.693 1.00 22.52  ? 248  ILE E CG2   1 
ATOM   15088 C CD1   . ILE E 1 248 ? -55.046  -2.931   -26.832 1.00 22.54  ? 248  ILE E CD1   1 
ATOM   15089 N N     . ALA E 1 249 ? -59.797  -2.381   -26.292 1.00 23.68  ? 249  ALA E N     1 
ATOM   15090 C CA    . ALA E 1 249 ? -60.776  -2.898   -25.348 1.00 23.73  ? 249  ALA E CA    1 
ATOM   15091 C C     . ALA E 1 249 ? -60.590  -4.413   -25.259 1.00 26.65  ? 249  ALA E C     1 
ATOM   15092 O O     . ALA E 1 249 ? -61.096  -5.153   -26.096 1.00 24.28  ? 249  ALA E O     1 
ATOM   15093 C CB    . ALA E 1 249 ? -62.173  -2.528   -25.799 1.00 18.95  ? 249  ALA E CB    1 
ATOM   15094 N N     . ALA E 1 250 ? -59.867  -4.841   -24.224 1.00 25.28  ? 250  ALA E N     1 
ATOM   15095 C CA    . ALA E 1 250 ? -59.323  -6.183   -24.108 1.00 29.62  ? 250  ALA E CA    1 
ATOM   15096 C C     . ALA E 1 250 ? -60.442  -7.233   -24.108 1.00 28.99  ? 250  ALA E C     1 
ATOM   15097 O O     . ALA E 1 250 ? -60.262  -8.308   -24.649 1.00 30.00  ? 250  ALA E O     1 
ATOM   15098 C CB    . ALA E 1 250 ? -58.458  -6.287   -22.835 1.00 23.79  ? 250  ALA E CB    1 
ATOM   15099 N N     . ASN E 1 251 ? -61.560  -6.952   -23.437 1.00 27.34  ? 251  ASN E N     1 
ATOM   15100 C CA    . ASN E 1 251 ? -62.629  -7.926   -23.332 1.00 27.91  ? 251  ASN E CA    1 
ATOM   15101 C C     . ASN E 1 251 ? -63.800  -7.601   -24.263 1.00 26.32  ? 251  ASN E C     1 
ATOM   15102 O O     . ASN E 1 251 ? -64.934  -8.012   -24.004 1.00 24.12  ? 251  ASN E O     1 
ATOM   15103 C CB    . ASN E 1 251 ? -63.071  -8.128   -21.889 1.00 27.41  ? 251  ASN E CB    1 
ATOM   15104 C CG    . ASN E 1 251 ? -61.984  -8.826   -21.096 1.00 34.31  ? 251  ASN E CG    1 
ATOM   15105 O OD1   . ASN E 1 251 ? -61.310  -9.773   -21.554 1.00 37.70  ? 251  ASN E OD1   1 
ATOM   15106 N ND2   . ASN E 1 251 ? -61.742  -8.314   -19.908 1.00 32.12  ? 251  ASN E ND2   1 
ATOM   15107 N N     . ASP E 1 252 ? -63.527  -6.831   -25.323 1.00 21.96  ? 252  ASP E N     1 
ATOM   15108 C CA    . ASP E 1 252 ? -64.471  -6.735   -26.422 1.00 24.85  ? 252  ASP E CA    1 
ATOM   15109 C C     . ASP E 1 252 ? -64.088  -7.813   -27.448 1.00 26.08  ? 252  ASP E C     1 
ATOM   15110 O O     . ASP E 1 252 ? -63.116  -7.634   -28.198 1.00 25.00  ? 252  ASP E O     1 
ATOM   15111 C CB    . ASP E 1 252 ? -64.493  -5.327   -26.992 1.00 21.69  ? 252  ASP E CB    1 
ATOM   15112 C CG    . ASP E 1 252 ? -65.370  -5.156   -28.227 1.00 27.20  ? 252  ASP E CG    1 
ATOM   15113 O OD1   . ASP E 1 252 ? -65.935  -6.185   -28.683 1.00 25.39  ? 252  ASP E OD1   1 
ATOM   15114 O OD2   . ASP E 1 252 ? -65.490  -4.000   -28.736 1.00 29.53  ? 252  ASP E OD2   1 
ATOM   15115 N N     . LEU E 1 253 ? -64.834  -8.937   -27.434 1.00 23.82  ? 253  LEU E N     1 
ATOM   15116 C CA    . LEU E 1 253 ? -64.558  -10.077  -28.311 1.00 23.06  ? 253  LEU E CA    1 
ATOM   15117 C C     . LEU E 1 253 ? -65.370  -9.962   -29.600 1.00 23.30  ? 253  LEU E C     1 
ATOM   15118 O O     . LEU E 1 253 ? -65.267  -10.805  -30.474 1.00 22.84  ? 253  LEU E O     1 
ATOM   15119 C CB    . LEU E 1 253 ? -64.903  -11.371  -27.573 1.00 19.47  ? 253  LEU E CB    1 
ATOM   15120 C CG    . LEU E 1 253 ? -64.331  -11.488  -26.156 1.00 19.36  ? 253  LEU E CG    1 
ATOM   15121 C CD1   . LEU E 1 253 ? -64.629  -12.836  -25.553 1.00 18.52  ? 253  LEU E CD1   1 
ATOM   15122 C CD2   . LEU E 1 253 ? -62.809  -11.129  -26.128 1.00 17.33  ? 253  LEU E CD2   1 
ATOM   15123 N N     . ASN E 1 254 ? -66.194  -8.914   -29.700 1.00 22.29  ? 254  ASN E N     1 
ATOM   15124 C CA    . ASN E 1 254 ? -67.159  -8.818   -30.781 1.00 21.56  ? 254  ASN E CA    1 
ATOM   15125 C C     . ASN E 1 254 ? -66.505  -8.209   -32.023 1.00 20.62  ? 254  ASN E C     1 
ATOM   15126 O O     . ASN E 1 254 ? -66.898  -7.137   -32.475 1.00 20.56  ? 254  ASN E O     1 
ATOM   15127 C CB    . ASN E 1 254 ? -68.405  -8.099   -30.280 1.00 19.40  ? 254  ASN E CB    1 
ATOM   15128 C CG    . ASN E 1 254 ? -69.524  -8.123   -31.296 1.00 22.71  ? 254  ASN E CG    1 
ATOM   15129 O OD1   . ASN E 1 254 ? -69.478  -8.916   -32.253 1.00 23.47  ? 254  ASN E OD1   1 
ATOM   15130 N ND2   . ASN E 1 254 ? -70.534  -7.272   -31.107 1.00 18.31  ? 254  ASN E ND2   1 
ATOM   15131 N N     . TYR E 1 255 ? -65.491  -8.886   -32.583 1.00 22.54  ? 255  TYR E N     1 
ATOM   15132 C CA    . TYR E 1 255 ? -64.816  -8.416   -33.792 1.00 22.98  ? 255  TYR E CA    1 
ATOM   15133 C C     . TYR E 1 255 ? -65.654  -8.739   -35.026 1.00 22.97  ? 255  TYR E C     1 
ATOM   15134 O O     . TYR E 1 255 ? -66.321  -9.763   -35.069 1.00 25.19  ? 255  TYR E O     1 
ATOM   15135 C CB    . TYR E 1 255 ? -63.480  -9.141   -33.882 1.00 23.46  ? 255  TYR E CB    1 
ATOM   15136 C CG    . TYR E 1 255 ? -62.391  -8.463   -33.072 1.00 23.25  ? 255  TYR E CG    1 
ATOM   15137 C CD1   . TYR E 1 255 ? -62.330  -8.620   -31.687 1.00 24.57  ? 255  TYR E CD1   1 
ATOM   15138 C CD2   . TYR E 1 255 ? -61.430  -7.666   -33.697 1.00 25.57  ? 255  TYR E CD2   1 
ATOM   15139 C CE1   . TYR E 1 255 ? -61.327  -8.007   -30.943 1.00 25.30  ? 255  TYR E CE1   1 
ATOM   15140 C CE2   . TYR E 1 255 ? -60.423  -7.043   -32.969 1.00 24.79  ? 255  TYR E CE2   1 
ATOM   15141 C CZ    . TYR E 1 255 ? -60.393  -7.209   -31.589 1.00 25.76  ? 255  TYR E CZ    1 
ATOM   15142 O OH    . TYR E 1 255 ? -59.437  -6.596   -30.864 1.00 29.03  ? 255  TYR E OH    1 
ATOM   15143 N N     . LYS E 1 256 ? -65.634  -7.846   -36.016 1.00 24.18  ? 256  LYS E N     1 
ATOM   15144 C CA    . LYS E 1 256 ? -66.236  -8.093   -37.314 1.00 22.32  ? 256  LYS E CA    1 
ATOM   15145 C C     . LYS E 1 256 ? -65.334  -9.071   -38.069 1.00 24.00  ? 256  LYS E C     1 
ATOM   15146 O O     . LYS E 1 256 ? -64.151  -9.239   -37.740 1.00 25.73  ? 256  LYS E O     1 
ATOM   15147 C CB    . LYS E 1 256 ? -66.253  -6.756   -38.050 1.00 24.78  ? 256  LYS E CB    1 
ATOM   15148 C CG    . LYS E 1 256 ? -67.120  -5.706   -37.367 1.00 25.75  ? 256  LYS E CG    1 
ATOM   15149 C CD    . LYS E 1 256 ? -67.004  -4.332   -38.027 1.00 28.37  ? 256  LYS E CD    1 
ATOM   15150 C CE    . LYS E 1 256 ? -67.757  -3.284   -37.217 1.00 27.74  ? 256  LYS E CE    1 
ATOM   15151 N NZ    . LYS E 1 256 ? -67.314  -3.237   -35.809 1.00 25.59  ? 256  LYS E NZ    1 
ATOM   15152 N N     . SER E 1 257 ? -65.899  -9.765   -39.068 1.00 20.44  ? 257  SER E N     1 
ATOM   15153 C CA    . SER E 1 257 ? -65.071  -10.675  -39.843 1.00 22.97  ? 257  SER E CA    1 
ATOM   15154 C C     . SER E 1 257 ? -64.136  -9.872   -40.746 1.00 21.96  ? 257  SER E C     1 
ATOM   15155 O O     . SER E 1 257 ? -64.490  -8.786   -41.211 1.00 19.53  ? 257  SER E O     1 
ATOM   15156 C CB    . SER E 1 257 ? -65.911  -11.608  -40.665 1.00 23.53  ? 257  SER E CB    1 
ATOM   15157 O OG    . SER E 1 257 ? -66.568  -10.867  -41.680 1.00 23.21  ? 257  SER E OG    1 
ATOM   15158 N N     . PRO E 1 258 ? -62.923  -10.397  -41.035 1.00 22.79  ? 258  PRO E N     1 
ATOM   15159 C CA    . PRO E 1 258 ? -62.092  -9.852   -42.114 1.00 20.94  ? 258  PRO E CA    1 
ATOM   15160 C C     . PRO E 1 258 ? -62.870  -9.665   -43.423 1.00 23.01  ? 258  PRO E C     1 
ATOM   15161 O O     . PRO E 1 258 ? -62.682  -8.674   -44.123 1.00 24.14  ? 258  PRO E O     1 
ATOM   15162 C CB    . PRO E 1 258 ? -60.892  -10.784  -42.141 1.00 21.19  ? 258  PRO E CB    1 
ATOM   15163 C CG    . PRO E 1 258 ? -60.851  -11.375  -40.726 1.00 20.50  ? 258  PRO E CG    1 
ATOM   15164 C CD    . PRO E 1 258 ? -62.295  -11.519  -40.320 1.00 20.42  ? 258  PRO E CD    1 
ATOM   15165 N N     . ALA E 1 259 ? -63.825  -10.556  -43.698 1.00 22.80  ? 259  ALA E N     1 
ATOM   15166 C CA    . ALA E 1 259 ? -64.617  -10.457  -44.925 1.00 22.72  ? 259  ALA E CA    1 
ATOM   15167 C C     . ALA E 1 259 ? -65.443  -9.172   -44.919 1.00 23.30  ? 259  ALA E C     1 
ATOM   15168 O O     . ALA E 1 259 ? -65.524  -8.472   -45.940 1.00 21.86  ? 259  ALA E O     1 
ATOM   15169 C CB    . ALA E 1 259 ? -65.529  -11.690  -45.130 1.00 16.10  ? 259  ALA E CB    1 
ATOM   15170 N N     . GLU E 1 260 ? -66.091  -8.889   -43.774 1.00 22.81  ? 260  GLU E N     1 
ATOM   15171 C CA    . GLU E 1 260 ? -66.913  -7.699   -43.670 1.00 24.52  ? 260  GLU E CA    1 
ATOM   15172 C C     . GLU E 1 260 ? -66.030  -6.452   -43.844 1.00 28.01  ? 260  GLU E C     1 
ATOM   15173 O O     . GLU E 1 260 ? -66.437  -5.473   -44.481 1.00 24.10  ? 260  GLU E O     1 
ATOM   15174 C CB    . GLU E 1 260 ? -67.691  -7.689   -42.357 1.00 26.11  ? 260  GLU E CB    1 
ATOM   15175 C CG    . GLU E 1 260 ? -68.500  -6.395   -42.218 1.00 34.27  ? 260  GLU E CG    1 
ATOM   15176 C CD    . GLU E 1 260 ? -69.365  -6.224   -40.964 1.00 42.52  ? 260  GLU E CD    1 
ATOM   15177 O OE1   . GLU E 1 260 ? -69.500  -7.192   -40.166 1.00 40.35  ? 260  GLU E OE1   1 
ATOM   15178 O OE2   . GLU E 1 260 ? -69.879  -5.103   -40.755 1.00 42.22  ? 260  GLU E OE2   1 
ATOM   15179 N N     . MET E 1 261 ? -64.801  -6.513   -43.302 1.00 22.29  ? 261  MET E N     1 
ATOM   15180 C CA    . MET E 1 261 ? -63.870  -5.419   -43.461 1.00 23.95  ? 261  MET E CA    1 
ATOM   15181 C C     . MET E 1 261 ? -63.585  -5.164   -44.942 1.00 26.55  ? 261  MET E C     1 
ATOM   15182 O O     . MET E 1 261 ? -63.679  -4.022   -45.409 1.00 24.78  ? 261  MET E O     1 
ATOM   15183 C CB    . MET E 1 261 ? -62.597  -5.689   -42.645 1.00 26.05  ? 261  MET E CB    1 
ATOM   15184 C CG    . MET E 1 261 ? -61.459  -4.726   -42.923 1.00 28.86  ? 261  MET E CG    1 
ATOM   15185 S SD    . MET E 1 261 ? -59.919  -5.211   -42.107 1.00 32.29  ? 261  MET E SD    1 
ATOM   15186 C CE    . MET E 1 261 ? -59.555  -6.758   -42.944 1.00 32.31  ? 261  MET E CE    1 
ATOM   15187 N N     . ILE E 1 262 ? -63.270  -6.234   -45.694 1.00 25.39  ? 262  ILE E N     1 
ATOM   15188 C CA    . ILE E 1 262 ? -62.995  -6.093   -47.114 1.00 24.87  ? 262  ILE E CA    1 
ATOM   15189 C C     . ILE E 1 262 ? -64.221  -5.545   -47.845 1.00 23.89  ? 262  ILE E C     1 
ATOM   15190 O O     . ILE E 1 262 ? -64.083  -4.628   -48.646 1.00 22.09  ? 262  ILE E O     1 
ATOM   15191 C CB    . ILE E 1 262 ? -62.469  -7.406   -47.721 1.00 22.37  ? 262  ILE E CB    1 
ATOM   15192 C CG1   . ILE E 1 262 ? -61.063  -7.643   -47.216 1.00 20.52  ? 262  ILE E CG1   1 
ATOM   15193 C CG2   . ILE E 1 262 ? -62.525  -7.356   -49.251 1.00 18.02  ? 262  ILE E CG2   1 
ATOM   15194 C CD1   . ILE E 1 262 ? -60.590  -9.067   -47.356 1.00 19.85  ? 262  ILE E CD1   1 
ATOM   15195 N N     . GLU E 1 263 ? -65.409  -6.076   -47.542 1.00 23.56  ? 263  GLU E N     1 
ATOM   15196 C CA    . GLU E 1 263 ? -66.618  -5.582   -48.188 1.00 24.89  ? 263  GLU E CA    1 
ATOM   15197 C C     . GLU E 1 263 ? -66.851  -4.099   -47.891 1.00 25.07  ? 263  GLU E C     1 
ATOM   15198 O O     . GLU E 1 263 ? -67.371  -3.387   -48.751 1.00 25.17  ? 263  GLU E O     1 
ATOM   15199 C CB    . GLU E 1 263 ? -67.858  -6.398   -47.830 1.00 27.03  ? 263  GLU E CB    1 
ATOM   15200 C CG    . GLU E 1 263 ? -67.801  -7.836   -48.342 1.00 33.97  ? 263  GLU E CG    1 
ATOM   15201 C CD    . GLU E 1 263 ? -69.065  -8.661   -48.186 1.00 38.55  ? 263  GLU E CD    1 
ATOM   15202 O OE1   . GLU E 1 263 ? -70.040  -8.104   -47.650 1.00 40.08  ? 263  GLU E OE1   1 
ATOM   15203 O OE2   . GLU E 1 263 ? -69.113  -9.841   -48.626 1.00 37.48  ? 263  GLU E OE2   1 
ATOM   15204 N N     . THR E 1 264 ? -66.476  -3.626   -46.692 1.00 24.22  ? 264  THR E N     1 
ATOM   15205 C CA    . THR E 1 264 ? -66.735  -2.239   -46.316 1.00 26.29  ? 264  THR E CA    1 
ATOM   15206 C C     . THR E 1 264 ? -65.785  -1.327   -47.089 1.00 25.26  ? 264  THR E C     1 
ATOM   15207 O O     . THR E 1 264 ? -66.199  -0.258   -47.555 1.00 26.09  ? 264  THR E O     1 
ATOM   15208 C CB    . THR E 1 264 ? -66.611  -2.031   -44.805 1.00 27.87  ? 264  THR E CB    1 
ATOM   15209 O OG1   . THR E 1 264 ? -67.523  -2.971   -44.242 1.00 28.63  ? 264  THR E OG1   1 
ATOM   15210 C CG2   . THR E 1 264 ? -67.047  -0.652   -44.352 1.00 26.21  ? 264  THR E CG2   1 
ATOM   15211 N N     . VAL E 1 265 ? -64.525  -1.763   -47.237 1.00 20.87  ? 265  VAL E N     1 
ATOM   15212 C CA    . VAL E 1 265 ? -63.585  -0.994   -48.030 1.00 23.72  ? 265  VAL E CA    1 
ATOM   15213 C C     . VAL E 1 265 ? -64.106  -0.863   -49.466 1.00 27.79  ? 265  VAL E C     1 
ATOM   15214 O O     . VAL E 1 265 ? -64.177  0.236    -50.018 1.00 26.40  ? 265  VAL E O     1 
ATOM   15215 C CB    . VAL E 1 265 ? -62.184  -1.619   -47.976 1.00 26.01  ? 265  VAL E CB    1 
ATOM   15216 C CG1   . VAL E 1 265 ? -61.250  -0.999   -49.014 1.00 25.77  ? 265  VAL E CG1   1 
ATOM   15217 C CG2   . VAL E 1 265 ? -61.605  -1.539   -46.564 1.00 22.83  ? 265  VAL E CG2   1 
ATOM   15218 N N     . ALA E 1 266 ? -64.541  -1.940   -50.053 1.00 26.06  ? 266  ALA E N     1 
ATOM   15219 C CA    . ALA E 1 266 ? -65.051  -1.899   -51.384 1.00 23.53  ? 266  ALA E CA    1 
ATOM   15220 C C     . ALA E 1 266 ? -66.286  -1.039   -51.513 1.00 25.15  ? 266  ALA E C     1 
ATOM   15221 O O     . ALA E 1 266 ? -66.437  -0.330   -52.449 1.00 27.02  ? 266  ALA E O     1 
ATOM   15222 C CB    . ALA E 1 266 ? -65.306  -3.296   -51.874 1.00 20.50  ? 266  ALA E CB    1 
ATOM   15223 N N     . HIS E 1 267 ? -67.150  -1.122   -50.527 1.00 26.63  ? 267  HIS E N     1 
ATOM   15224 C CA    . HIS E 1 267 ? -68.384  -0.393   -50.465 1.00 25.56  ? 267  HIS E CA    1 
ATOM   15225 C C     . HIS E 1 267 ? -68.199  1.113    -50.432 1.00 26.29  ? 267  HIS E C     1 
ATOM   15226 O O     . HIS E 1 267 ? -68.963  1.820    -50.994 1.00 25.35  ? 267  HIS E O     1 
ATOM   15227 C CB    . HIS E 1 267 ? -69.232  -0.866   -49.307 1.00 24.61  ? 267  HIS E CB    1 
ATOM   15228 C CG    . HIS E 1 267 ? -70.440  -0.038   -49.089 1.00 28.84  ? 267  HIS E CG    1 
ATOM   15229 N ND1   . HIS E 1 267 ? -71.538  -0.101   -49.899 1.00 30.45  ? 267  HIS E ND1   1 
ATOM   15230 C CD2   . HIS E 1 267 ? -70.701  0.912    -48.178 1.00 29.14  ? 267  HIS E CD2   1 
ATOM   15231 C CE1   . HIS E 1 267 ? -72.431  0.765    -49.487 1.00 29.91  ? 267  HIS E CE1   1 
ATOM   15232 N NE2   . HIS E 1 267 ? -71.947  1.392    -48.443 1.00 29.57  ? 267  HIS E NE2   1 
ATOM   15233 N N     . ALA E 1 268 ? -67.168  1.565    -49.757 1.00 24.49  ? 268  ALA E N     1 
ATOM   15234 C CA    . ALA E 1 268 ? -66.863  2.960    -49.654 1.00 25.34  ? 268  ALA E CA    1 
ATOM   15235 C C     . ALA E 1 268 ? -66.556  3.522    -51.011 1.00 25.97  ? 268  ALA E C     1 
ATOM   15236 O O     . ALA E 1 268 ? -67.006  4.563    -51.365 1.00 26.11  ? 268  ALA E O     1 
ATOM   15237 C CB    . ALA E 1 268 ? -65.696  3.167    -48.719 1.00 23.13  ? 268  ALA E CB    1 
ATOM   15238 N N     . ARG E 1 269 ? -65.781  2.792    -51.771 1.00 23.87  ? 269  ARG E N     1 
ATOM   15239 C CA    . ARG E 1 269 ? -65.435  3.174    -53.109 1.00 25.08  ? 269  ARG E CA    1 
ATOM   15240 C C     . ARG E 1 269 ? -66.639  3.194    -54.018 1.00 28.01  ? 269  ARG E C     1 
ATOM   15241 O O     . ARG E 1 269 ? -66.755  4.040    -54.832 1.00 30.40  ? 269  ARG E O     1 
ATOM   15242 C CB    . ARG E 1 269 ? -64.337  2.311    -53.691 1.00 22.14  ? 269  ARG E CB    1 
ATOM   15243 C CG    . ARG E 1 269 ? -63.125  2.180    -52.829 1.00 23.88  ? 269  ARG E CG    1 
ATOM   15244 C CD    . ARG E 1 269 ? -62.645  3.488    -52.300 1.00 27.65  ? 269  ARG E CD    1 
ATOM   15245 N NE    . ARG E 1 269 ? -61.813  4.203    -53.232 1.00 29.74  ? 269  ARG E NE    1 
ATOM   15246 C CZ    . ARG E 1 269 ? -61.610  5.499    -53.207 1.00 28.88  ? 269  ARG E CZ    1 
ATOM   15247 N NH1   . ARG E 1 269 ? -62.195  6.230    -52.324 1.00 27.31  ? 269  ARG E NH1   1 
ATOM   15248 N NH2   . ARG E 1 269 ? -60.826  6.053    -54.067 1.00 28.10  ? 269  ARG E NH2   1 
ATOM   15249 N N     . HIS E 1 270 ? -67.532  2.248    -53.862 1.00 27.15  ? 270  HIS E N     1 
ATOM   15250 C CA    . HIS E 1 270 ? -68.730  2.184    -54.644 1.00 27.57  ? 270  HIS E CA    1 
ATOM   15251 C C     . HIS E 1 270 ? -69.608  3.414    -54.425 1.00 28.60  ? 270  HIS E C     1 
ATOM   15252 O O     . HIS E 1 270 ? -70.191  3.902    -55.329 1.00 29.05  ? 270  HIS E O     1 
ATOM   15253 C CB    . HIS E 1 270 ? -69.468  0.888    -54.359 1.00 28.70  ? 270  HIS E CB    1 
ATOM   15254 C CG    . HIS E 1 270 ? -70.790  0.792    -55.026 1.00 31.11  ? 270  HIS E CG    1 
ATOM   15255 N ND1   . HIS E 1 270 ? -71.910  0.343    -54.387 1.00 34.39  ? 270  HIS E ND1   1 
ATOM   15256 C CD2   . HIS E 1 270 ? -71.175  1.107    -56.273 1.00 29.32  ? 270  HIS E CD2   1 
ATOM   15257 C CE1   . HIS E 1 270 ? -72.926  0.375    -55.213 1.00 30.73  ? 270  HIS E CE1   1 
ATOM   15258 N NE2   . HIS E 1 270 ? -72.505  0.840    -56.363 1.00 31.38  ? 270  HIS E NE2   1 
ATOM   15259 N N     . ILE E 1 271 ? -69.690  3.905    -53.213 1.00 29.34  ? 271  ILE E N     1 
ATOM   15260 C CA    . ILE E 1 271 ? -70.456  5.094    -52.942 1.00 28.42  ? 271  ILE E CA    1 
ATOM   15261 C C     . ILE E 1 271 ? -69.683  6.413    -53.144 1.00 30.28  ? 271  ILE E C     1 
ATOM   15262 O O     . ILE E 1 271 ? -70.219  7.442    -52.972 1.00 31.57  ? 271  ILE E O     1 
ATOM   15263 C CB    . ILE E 1 271 ? -71.154  5.054    -51.581 1.00 25.86  ? 271  ILE E CB    1 
ATOM   15264 C CG1   . ILE E 1 271 ? -70.158  5.148    -50.452 1.00 26.60  ? 271  ILE E CG1   1 
ATOM   15265 C CG2   . ILE E 1 271 ? -72.005  3.826    -51.471 1.00 24.84  ? 271  ILE E CG2   1 
ATOM   15266 C CD1   . ILE E 1 271 ? -70.770  5.375    -49.116 1.00 29.75  ? 271  ILE E CD1   1 
ATOM   15267 N N     . GLY E 1 272 ? -68.411  6.357    -53.468 1.00 25.72  ? 272  GLY E N     1 
ATOM   15268 C CA    . GLY E 1 272 ? -67.632  7.559    -53.738 1.00 27.27  ? 272  GLY E CA    1 
ATOM   15269 C C     . GLY E 1 272 ? -67.059  8.215    -52.475 1.00 28.71  ? 272  GLY E C     1 
ATOM   15270 O O     . GLY E 1 272 ? -67.051  9.437    -52.362 1.00 33.64  ? 272  GLY E O     1 
ATOM   15271 N N     . ALA E 1 273 ? -66.557  7.404    -51.535 1.00 26.32  ? 273  ALA E N     1 
ATOM   15272 C CA    . ALA E 1 273 ? -66.031  7.886    -50.265 1.00 29.59  ? 273  ALA E CA    1 
ATOM   15273 C C     . ALA E 1 273 ? -64.663  7.260    -50.036 1.00 28.91  ? 273  ALA E C     1 
ATOM   15274 O O     . ALA E 1 273 ? -64.352  6.218    -50.615 1.00 31.04  ? 273  ALA E O     1 
ATOM   15275 C CB    . ALA E 1 273 ? -66.981  7.541    -49.118 1.00 24.61  ? 273  ALA E CB    1 
ATOM   15276 N N     . ASN E 1 274 ? -63.859  7.904    -49.185 1.00 29.25  ? 274  ASN E N     1 
ATOM   15277 C CA    . ASN E 1 274 ? -62.704  7.232    -48.615 1.00 26.92  ? 274  ASN E CA    1 
ATOM   15278 C C     . ASN E 1 274 ? -63.168  6.342    -47.457 1.00 25.24  ? 274  ASN E C     1 
ATOM   15279 O O     . ASN E 1 274 ? -64.298  6.482    -46.962 1.00 24.50  ? 274  ASN E O     1 
ATOM   15280 C CB    . ASN E 1 274 ? -61.679  8.250    -48.126 1.00 25.28  ? 274  ASN E CB    1 
ATOM   15281 C CG    . ASN E 1 274 ? -60.849  8.838    -49.242 1.00 29.93  ? 274  ASN E CG    1 
ATOM   15282 O OD1   . ASN E 1 274 ? -61.232  8.760    -50.422 1.00 30.19  ? 274  ASN E OD1   1 
ATOM   15283 N ND2   . ASN E 1 274 ? -59.724  9.451    -48.876 1.00 26.15  ? 274  ASN E ND2   1 
ATOM   15284 N N     . ILE E 1 275 ? -62.267  5.471    -46.987 1.00 23.86  ? 275  ILE E N     1 
ATOM   15285 C CA    . ILE E 1 275 ? -62.553  4.639    -45.825 1.00 24.72  ? 275  ILE E CA    1 
ATOM   15286 C C     . ILE E 1 275 ? -61.360  4.720    -44.880 1.00 23.84  ? 275  ILE E C     1 
ATOM   15287 O O     . ILE E 1 275 ? -60.206  4.623    -45.315 1.00 24.12  ? 275  ILE E O     1 
ATOM   15288 C CB    . ILE E 1 275 ? -62.844  3.185    -46.260 1.00 27.76  ? 275  ILE E CB    1 
ATOM   15289 C CG1   . ILE E 1 275 ? -62.921  2.236    -45.089 1.00 26.86  ? 275  ILE E CG1   1 
ATOM   15290 C CG2   . ILE E 1 275 ? -61.773  2.680    -47.229 1.00 25.34  ? 275  ILE E CG2   1 
ATOM   15291 C CD1   . ILE E 1 275 ? -64.290  2.070    -44.505 1.00 30.38  ? 275  ILE E CD1   1 
ATOM   15292 N N     . LEU E 1 276 ? -61.656  4.893    -43.579 1.00 28.43  ? 276  LEU E N     1 
ATOM   15293 C CA    . LEU E 1 276 ? -60.673  4.730    -42.509 1.00 26.79  ? 276  LEU E CA    1 
ATOM   15294 C C     . LEU E 1 276 ? -60.913  3.393    -41.818 1.00 24.61  ? 276  LEU E C     1 
ATOM   15295 O O     . LEU E 1 276 ? -62.049  3.106    -41.428 1.00 24.49  ? 276  LEU E O     1 
ATOM   15296 C CB    . LEU E 1 276 ? -60.821  5.850    -41.479 1.00 28.61  ? 276  LEU E CB    1 
ATOM   15297 C CG    . LEU E 1 276 ? -60.444  7.269    -41.929 1.00 31.98  ? 276  LEU E CG    1 
ATOM   15298 C CD1   . LEU E 1 276 ? -60.587  8.237    -40.743 1.00 27.36  ? 276  LEU E CD1   1 
ATOM   15299 C CD2   . LEU E 1 276 ? -59.009  7.265    -42.448 1.00 31.61  ? 276  LEU E CD2   1 
ATOM   15300 N N     . VAL E 1 277 ? -59.842  2.607    -41.638 1.00 22.98  ? 277  VAL E N     1 
ATOM   15301 C CA    . VAL E 1 277 ? -59.903  1.415    -40.814 1.00 22.17  ? 277  VAL E CA    1 
ATOM   15302 C C     . VAL E 1 277 ? -59.166  1.727    -39.519 1.00 23.31  ? 277  VAL E C     1 
ATOM   15303 O O     . VAL E 1 277 ? -57.996  2.117    -39.554 1.00 23.01  ? 277  VAL E O     1 
ATOM   15304 C CB    . VAL E 1 277 ? -59.264  0.219    -41.559 1.00 22.92  ? 277  VAL E CB    1 
ATOM   15305 C CG1   . VAL E 1 277 ? -59.163  -1.042   -40.686 1.00 22.45  ? 277  VAL E CG1   1 
ATOM   15306 C CG2   . VAL E 1 277 ? -60.025  -0.095   -42.840 1.00 22.45  ? 277  VAL E CG2   1 
ATOM   15307 N N     . ASN E 1 278 ? -59.856  1.545    -38.389 1.00 25.27  ? 278  ASN E N     1 
ATOM   15308 C CA    . ASN E 1 278 ? -59.348  2.005    -37.108 1.00 25.00  ? 278  ASN E CA    1 
ATOM   15309 C C     . ASN E 1 278 ? -58.621  0.900    -36.354 1.00 26.39  ? 278  ASN E C     1 
ATOM   15310 O O     . ASN E 1 278 ? -59.104  -0.226   -36.287 1.00 28.45  ? 278  ASN E O     1 
ATOM   15311 C CB    . ASN E 1 278 ? -60.482  2.462    -36.204 1.00 26.27  ? 278  ASN E CB    1 
ATOM   15312 C CG    . ASN E 1 278 ? -59.918  2.890    -34.867 1.00 30.21  ? 278  ASN E CG    1 
ATOM   15313 O OD1   . ASN E 1 278 ? -59.175  3.881    -34.815 1.00 25.47  ? 278  ASN E OD1   1 
ATOM   15314 N ND2   . ASN E 1 278 ? -60.210  2.133    -33.809 1.00 24.42  ? 278  ASN E ND2   1 
ATOM   15315 N N     . ILE E 1 279 ? -57.488  1.243    -35.731 1.00 27.41  ? 279  ILE E N     1 
ATOM   15316 C CA    . ILE E 1 279 ? -56.869  0.366    -34.735 1.00 24.23  ? 279  ILE E CA    1 
ATOM   15317 C C     . ILE E 1 279 ? -56.627  1.174    -33.453 1.00 27.38  ? 279  ILE E C     1 
ATOM   15318 O O     . ILE E 1 279 ? -56.317  2.376    -33.484 1.00 32.84  ? 279  ILE E O     1 
ATOM   15319 C CB    . ILE E 1 279 ? -55.561  -0.234   -35.281 1.00 27.05  ? 279  ILE E CB    1 
ATOM   15320 C CG1   . ILE E 1 279 ? -54.506  0.822    -35.434 1.00 30.97  ? 279  ILE E CG1   1 
ATOM   15321 C CG2   . ILE E 1 279 ? -55.751  -0.989   -36.615 1.00 26.54  ? 279  ILE E CG2   1 
ATOM   15322 C CD1   . ILE E 1 279 ? -53.166  0.250    -35.839 1.00 34.81  ? 279  ILE E CD1   1 
ATOM   15323 N N     . GLY E 1 280 ? -56.769  0.526    -32.291 1.00 28.19  ? 280  GLY E N     1 
ATOM   15324 C CA    . GLY E 1 280 ? -56.450  1.150    -31.018 1.00 22.18  ? 280  GLY E CA    1 
ATOM   15325 C C     . GLY E 1 280 ? -55.106  0.640    -30.496 1.00 28.55  ? 280  GLY E C     1 
ATOM   15326 O O     . GLY E 1 280 ? -54.960  -0.570   -30.366 1.00 28.76  ? 280  GLY E O     1 
ATOM   15327 N N     . LEU E 1 281 ? -54.133  1.539    -30.197 1.00 26.34  ? 281  LEU E N     1 
ATOM   15328 C CA    . LEU E 1 281 ? -52.840  1.082    -29.695 1.00 22.29  ? 281  LEU E CA    1 
ATOM   15329 C C     . LEU E 1 281 ? -52.955  0.622    -28.246 1.00 21.81  ? 281  LEU E C     1 
ATOM   15330 O O     . LEU E 1 281 ? -53.903  1.002    -27.544 1.00 21.21  ? 281  LEU E O     1 
ATOM   15331 C CB    . LEU E 1 281 ? -51.768  2.153    -29.860 1.00 22.25  ? 281  LEU E CB    1 
ATOM   15332 C CG    . LEU E 1 281 ? -51.591  2.731    -31.271 1.00 26.73  ? 281  LEU E CG    1 
ATOM   15333 C CD1   . LEU E 1 281 ? -50.432  3.730    -31.348 1.00 22.72  ? 281  LEU E CD1   1 
ATOM   15334 C CD2   . LEU E 1 281 ? -51.418  1.646    -32.346 1.00 20.24  ? 281  LEU E CD2   1 
ATOM   15335 N N     . THR E 1 282 ? -51.989  -0.199   -27.805 1.00 21.20  ? 282  THR E N     1 
ATOM   15336 C CA    . THR E 1 282 ? -51.847  -0.540   -26.386 1.00 25.25  ? 282  THR E CA    1 
ATOM   15337 C C     . THR E 1 282 ? -51.451  0.711    -25.593 1.00 26.78  ? 282  THR E C     1 
ATOM   15338 O O     . THR E 1 282 ? -51.045  1.736    -26.163 1.00 24.78  ? 282  THR E O     1 
ATOM   15339 C CB    . THR E 1 282 ? -50.814  -1.658   -26.174 1.00 25.57  ? 282  THR E CB    1 
ATOM   15340 O OG1   . THR E 1 282 ? -49.549  -1.058   -26.451 1.00 27.42  ? 282  THR E OG1   1 
ATOM   15341 C CG2   . THR E 1 282 ? -51.044  -2.880   -27.059 1.00 21.01  ? 282  THR E CG2   1 
ATOM   15342 N N     . GLY E 1 283 ? -51.520  0.598    -24.262 1.00 27.41  ? 283  GLY E N     1 
ATOM   15343 C CA    . GLY E 1 283 ? -51.143  1.686    -23.376 1.00 28.31  ? 283  GLY E CA    1 
ATOM   15344 C C     . GLY E 1 283 ? -49.804  2.312    -23.784 1.00 26.48  ? 283  GLY E C     1 
ATOM   15345 O O     . GLY E 1 283 ? -49.690  3.544    -23.880 1.00 31.65  ? 283  GLY E O     1 
ATOM   15346 N N     . THR E 1 284 ? -48.818  1.466    -24.080 1.00 23.43  ? 284  THR E N     1 
ATOM   15347 C CA    . THR E 1 284 ? -47.463  1.917    -24.370 1.00 27.33  ? 284  THR E CA    1 
ATOM   15348 C C     . THR E 1 284 ? -47.257  2.219    -25.858 1.00 28.70  ? 284  THR E C     1 
ATOM   15349 O O     . THR E 1 284 ? -46.133  2.540    -26.266 1.00 29.58  ? 284  THR E O     1 
ATOM   15350 C CB    . THR E 1 284 ? -46.445  0.887    -23.868 1.00 34.20  ? 284  THR E CB    1 
ATOM   15351 O OG1   . THR E 1 284 ? -46.805  -0.300   -24.569 1.00 36.68  ? 284  THR E OG1   1 
ATOM   15352 C CG2   . THR E 1 284 ? -46.462  0.677    -22.356 1.00 23.55  ? 284  THR E CG2   1 
ATOM   15353 N N     . GLY E 1 285 ? -48.316  2.115    -26.688 1.00 27.75  ? 285  GLY E N     1 
ATOM   15354 C CA    . GLY E 1 285 ? -48.199  2.565    -28.065 1.00 25.33  ? 285  GLY E CA    1 
ATOM   15355 C C     . GLY E 1 285 ? -47.873  1.467    -29.097 1.00 27.72  ? 285  GLY E C     1 
ATOM   15356 O O     . GLY E 1 285 ? -47.524  1.802    -30.232 1.00 27.83  ? 285  GLY E O     1 
ATOM   15357 N N     . ALA E 1 286 ? -48.014  0.168    -28.750 1.00 28.28  ? 286  ALA E N     1 
ATOM   15358 C CA    . ALA E 1 286 ? -47.834  -0.895   -29.745 1.00 26.95  ? 286  ALA E CA    1 
ATOM   15359 C C     . ALA E 1 286 ? -49.133  -1.126   -30.536 1.00 27.49  ? 286  ALA E C     1 
ATOM   15360 O O     . ALA E 1 286 ? -50.242  -0.902   -30.032 1.00 27.75  ? 286  ALA E O     1 
ATOM   15361 C CB    . ALA E 1 286 ? -47.416  -2.191   -29.069 1.00 20.06  ? 286  ALA E CB    1 
ATOM   15362 N N     . ILE E 1 287 ? -48.990  -1.596   -31.784 1.00 27.30  ? 287  ILE E N     1 
ATOM   15363 C CA    . ILE E 1 287 ? -50.121  -2.151   -32.512 1.00 26.02  ? 287  ILE E CA    1 
ATOM   15364 C C     . ILE E 1 287 ? -50.445  -3.514   -31.914 1.00 22.84  ? 287  ILE E C     1 
ATOM   15365 O O     . ILE E 1 287 ? -49.595  -4.389   -31.884 1.00 24.57  ? 287  ILE E O     1 
ATOM   15366 C CB    . ILE E 1 287 ? -49.819  -2.262   -34.007 1.00 29.56  ? 287  ILE E CB    1 
ATOM   15367 C CG1   . ILE E 1 287 ? -49.397  -0.938   -34.583 1.00 27.35  ? 287  ILE E CG1   1 
ATOM   15368 C CG2   . ILE E 1 287 ? -51.005  -2.886   -34.748 1.00 27.62  ? 287  ILE E CG2   1 
ATOM   15369 C CD1   . ILE E 1 287 ? -49.181  -0.968   -36.089 1.00 30.09  ? 287  ILE E CD1   1 
ATOM   15370 N N     . PRO E 1 288 ? -51.651  -3.755   -31.386 1.00 22.18  ? 288  PRO E N     1 
ATOM   15371 C CA    . PRO E 1 288 ? -51.940  -5.059   -30.791 1.00 25.34  ? 288  PRO E CA    1 
ATOM   15372 C C     . PRO E 1 288 ? -51.982  -6.179   -31.843 1.00 29.63  ? 288  PRO E C     1 
ATOM   15373 O O     . PRO E 1 288 ? -52.277  -5.914   -33.019 1.00 25.29  ? 288  PRO E O     1 
ATOM   15374 C CB    . PRO E 1 288 ? -53.303  -4.880   -30.121 1.00 22.87  ? 288  PRO E CB    1 
ATOM   15375 C CG    . PRO E 1 288 ? -53.878  -3.588   -30.683 1.00 23.52  ? 288  PRO E CG    1 
ATOM   15376 C CD    . PRO E 1 288 ? -52.772  -2.806   -31.371 1.00 22.61  ? 288  PRO E CD    1 
ATOM   15377 N N     . ALA E 1 289 ? -51.712  -7.413   -31.400 1.00 28.83  ? 289  ALA E N     1 
ATOM   15378 C CA    . ALA E 1 289 ? -51.631  -8.567   -32.296 1.00 31.07  ? 289  ALA E CA    1 
ATOM   15379 C C     . ALA E 1 289 ? -52.903  -8.721   -33.151 1.00 28.24  ? 289  ALA E C     1 
ATOM   15380 O O     . ALA E 1 289 ? -52.808  -8.958   -34.353 1.00 29.00  ? 289  ALA E O     1 
ATOM   15381 C CB    . ALA E 1 289 ? -51.263  -9.846   -31.523 1.00 23.11  ? 289  ALA E CB    1 
ATOM   15382 N N     . ALA E 1 290 ? -54.085  -8.530   -32.547 1.00 26.60  ? 290  ALA E N     1 
ATOM   15383 C CA    . ALA E 1 290 ? -55.335  -8.696   -33.280 1.00 27.02  ? 290  ALA E CA    1 
ATOM   15384 C C     . ALA E 1 290 ? -55.402  -7.739   -34.463 1.00 27.98  ? 290  ALA E C     1 
ATOM   15385 O O     . ALA E 1 290 ? -55.787  -8.122   -35.566 1.00 27.85  ? 290  ALA E O     1 
ATOM   15386 C CB    . ALA E 1 290 ? -56.553  -8.556   -32.379 1.00 26.41  ? 290  ALA E CB    1 
ATOM   15387 N N     . ALA E 1 291 ? -54.995  -6.490   -34.239 1.00 27.37  ? 291  ALA E N     1 
ATOM   15388 C CA    . ALA E 1 291 ? -55.069  -5.489   -35.289 1.00 28.32  ? 291  ALA E CA    1 
ATOM   15389 C C     . ALA E 1 291 ? -54.106  -5.849   -36.416 1.00 28.22  ? 291  ALA E C     1 
ATOM   15390 O O     . ALA E 1 291 ? -54.443  -5.647   -37.580 1.00 31.55  ? 291  ALA E O     1 
ATOM   15391 C CB    . ALA E 1 291 ? -54.787  -4.111   -34.727 1.00 23.08  ? 291  ALA E CB    1 
ATOM   15392 N N     . GLN E 1 292 ? -52.918  -6.374   -36.063 1.00 29.29  ? 292  GLN E N     1 
ATOM   15393 C CA    . GLN E 1 292 ? -51.948  -6.793   -37.060 1.00 32.94  ? 292  GLN E CA    1 
ATOM   15394 C C     . GLN E 1 292 ? -52.554  -7.865   -37.976 1.00 28.72  ? 292  GLN E C     1 
ATOM   15395 O O     . GLN E 1 292 ? -52.355  -7.805   -39.187 1.00 26.24  ? 292  GLN E O     1 
ATOM   15396 C CB    . GLN E 1 292 ? -50.619  -7.242   -36.461 1.00 35.79  ? 292  GLN E CB    1 
ATOM   15397 C CG    . GLN E 1 292 ? -49.630  -6.122   -36.177 1.00 49.86  ? 292  GLN E CG    1 
ATOM   15398 C CD    . GLN E 1 292 ? -48.504  -6.571   -35.260 1.00 69.19  ? 292  GLN E CD    1 
ATOM   15399 O OE1   . GLN E 1 292 ? -48.262  -6.017   -34.180 1.00 58.59  ? 292  GLN E OE1   1 
ATOM   15400 N NE2   . GLN E 1 292 ? -47.799  -7.616   -35.671 1.00 74.22  ? 292  GLN E NE2   1 
ATOM   15401 N N     . THR E 1 293 ? -53.311  -8.817   -37.415 1.00 26.27  ? 293  THR E N     1 
ATOM   15402 C CA    . THR E 1 293 ? -53.935  -9.869   -38.215 1.00 25.57  ? 293  THR E CA    1 
ATOM   15403 C C     . THR E 1 293 ? -54.860  -9.235   -39.265 1.00 25.55  ? 293  THR E C     1 
ATOM   15404 O O     . THR E 1 293 ? -54.763  -9.571   -40.434 1.00 28.23  ? 293  THR E O     1 
ATOM   15405 C CB    . THR E 1 293 ? -54.687  -10.850  -37.308 1.00 24.53  ? 293  THR E CB    1 
ATOM   15406 O OG1   . THR E 1 293 ? -53.683  -11.586  -36.627 1.00 28.54  ? 293  THR E OG1   1 
ATOM   15407 C CG2   . THR E 1 293 ? -55.649  -11.756  -38.055 1.00 24.09  ? 293  THR E CG2   1 
ATOM   15408 N N     . TYR E 1 294 ? -55.727  -8.305   -38.851 1.00 21.80  ? 294  TYR E N     1 
ATOM   15409 C CA    . TYR E 1 294 ? -56.657  -7.658   -39.762 1.00 23.53  ? 294  TYR E CA    1 
ATOM   15410 C C     . TYR E 1 294 ? -55.906  -6.838   -40.816 1.00 24.96  ? 294  TYR E C     1 
ATOM   15411 O O     . TYR E 1 294 ? -56.276  -6.828   -41.984 1.00 26.29  ? 294  TYR E O     1 
ATOM   15412 C CB    . TYR E 1 294 ? -57.691  -6.810   -39.014 1.00 21.23  ? 294  TYR E CB    1 
ATOM   15413 C CG    . TYR E 1 294 ? -58.803  -7.657   -38.426 1.00 22.11  ? 294  TYR E CG    1 
ATOM   15414 C CD1   . TYR E 1 294 ? -58.576  -8.483   -37.320 1.00 23.17  ? 294  TYR E CD1   1 
ATOM   15415 C CD2   . TYR E 1 294 ? -60.063  -7.687   -39.010 1.00 20.98  ? 294  TYR E CD2   1 
ATOM   15416 C CE1   . TYR E 1 294 ? -59.597  -9.245   -36.765 1.00 21.62  ? 294  TYR E CE1   1 
ATOM   15417 C CE2   . TYR E 1 294 ? -61.093  -8.454   -38.475 1.00 20.47  ? 294  TYR E CE2   1 
ATOM   15418 C CZ    . TYR E 1 294 ? -60.856  -9.233   -37.352 1.00 23.60  ? 294  TYR E CZ    1 
ATOM   15419 O OH    . TYR E 1 294 ? -61.865  -10.004  -36.823 1.00 27.18  ? 294  TYR E OH    1 
ATOM   15420 N N     . MET E 1 295 ? -54.829  -6.183   -40.418 1.00 25.63  ? 295  MET E N     1 
ATOM   15421 C CA    . MET E 1 295 ? -54.034  -5.416   -41.363 1.00 29.58  ? 295  MET E CA    1 
ATOM   15422 C C     . MET E 1 295 ? -53.371  -6.299   -42.423 1.00 26.63  ? 295  MET E C     1 
ATOM   15423 O O     . MET E 1 295 ? -53.355  -5.926   -43.596 1.00 26.89  ? 295  MET E O     1 
ATOM   15424 C CB    . MET E 1 295 ? -53.032  -4.516   -40.640 1.00 28.80  ? 295  MET E CB    1 
ATOM   15425 C CG    . MET E 1 295 ? -53.751  -3.362   -39.942 1.00 33.86  ? 295  MET E CG    1 
ATOM   15426 S SD    . MET E 1 295 ? -52.522  -2.497   -38.919 1.00 40.04  ? 295  MET E SD    1 
ATOM   15427 C CE    . MET E 1 295 ? -51.879  -1.526   -40.284 1.00 33.83  ? 295  MET E CE    1 
ATOM   15428 N N     . HIS E 1 296 ? -52.839  -7.457   -42.024 1.00 23.88  ? 296  HIS E N     1 
ATOM   15429 C CA    . HIS E 1 296 ? -52.244  -8.389   -42.980 1.00 27.34  ? 296  HIS E CA    1 
ATOM   15430 C C     . HIS E 1 296 ? -53.276  -8.867   -43.998 1.00 26.37  ? 296  HIS E C     1 
ATOM   15431 O O     . HIS E 1 296 ? -52.989  -8.885   -45.193 1.00 29.61  ? 296  HIS E O     1 
ATOM   15432 C CB    . HIS E 1 296 ? -51.465  -9.518   -42.297 1.00 31.15  ? 296  HIS E CB    1 
ATOM   15433 C CG    . HIS E 1 296 ? -50.157  -9.036   -41.757 1.00 44.22  ? 296  HIS E CG    1 
ATOM   15434 N ND1   . HIS E 1 296 ? -49.762  -9.183   -40.443 1.00 47.05  ? 296  HIS E ND1   1 
ATOM   15435 C CD2   . HIS E 1 296 ? -49.158  -8.387   -42.370 1.00 52.49  ? 296  HIS E CD2   1 
ATOM   15436 C CE1   . HIS E 1 296 ? -48.576  -8.626   -40.274 1.00 45.01  ? 296  HIS E CE1   1 
ATOM   15437 N NE2   . HIS E 1 296 ? -48.182  -8.153   -41.433 1.00 50.34  ? 296  HIS E NE2   1 
ATOM   15438 N N     . LEU E 1 297 ? -54.481  -9.230   -43.528 1.00 25.77  ? 297  LEU E N     1 
ATOM   15439 C CA    . LEU E 1 297 ? -55.528  -9.701   -44.418 1.00 23.34  ? 297  LEU E CA    1 
ATOM   15440 C C     . LEU E 1 297 ? -55.950  -8.578   -45.360 1.00 26.17  ? 297  LEU E C     1 
ATOM   15441 O O     . LEU E 1 297 ? -56.004  -8.788   -46.573 1.00 25.44  ? 297  LEU E O     1 
ATOM   15442 C CB    . LEU E 1 297 ? -56.696  -10.325  -43.668 1.00 22.49  ? 297  LEU E CB    1 
ATOM   15443 C CG    . LEU E 1 297 ? -56.337  -11.574  -42.859 1.00 22.86  ? 297  LEU E CG    1 
ATOM   15444 C CD1   . LEU E 1 297 ? -57.476  -11.948  -41.919 1.00 20.18  ? 297  LEU E CD1   1 
ATOM   15445 C CD2   . LEU E 1 297 ? -55.941  -12.769  -43.801 1.00 24.17  ? 297  LEU E CD2   1 
ATOM   15446 N N     . LEU E 1 298 ? -56.205  -7.383   -44.820 1.00 26.10  ? 298  LEU E N     1 
ATOM   15447 C CA    . LEU E 1 298 ? -56.627  -6.276   -45.663 1.00 24.70  ? 298  LEU E CA    1 
ATOM   15448 C C     . LEU E 1 298 ? -55.547  -5.984   -46.705 1.00 24.38  ? 298  LEU E C     1 
ATOM   15449 O O     . LEU E 1 298 ? -55.864  -5.707   -47.865 1.00 27.24  ? 298  LEU E O     1 
ATOM   15450 C CB    . LEU E 1 298 ? -56.898  -5.057   -44.778 1.00 27.87  ? 298  LEU E CB    1 
ATOM   15451 C CG    . LEU E 1 298 ? -57.294  -3.781   -45.537 1.00 27.89  ? 298  LEU E CG    1 
ATOM   15452 C CD1   . LEU E 1 298 ? -58.517  -4.037   -46.385 1.00 25.96  ? 298  LEU E CD1   1 
ATOM   15453 C CD2   . LEU E 1 298 ? -57.566  -2.661   -44.563 1.00 27.96  ? 298  LEU E CD2   1 
ATOM   15454 N N     . GLY E 1 299 ? -54.277  -6.045   -46.267 1.00 21.47  ? 299  GLY E N     1 
ATOM   15455 C CA    . GLY E 1 299 ? -53.133  -5.759   -47.113 1.00 22.11  ? 299  GLY E CA    1 
ATOM   15456 C C     . GLY E 1 299 ? -53.064  -6.683   -48.331 1.00 24.73  ? 299  GLY E C     1 
ATOM   15457 O O     . GLY E 1 299 ? -52.704  -6.237   -49.424 1.00 25.88  ? 299  GLY E O     1 
ATOM   15458 N N     . ARG E 1 300 ? -53.423  -7.965   -48.155 1.00 25.67  ? 300  ARG E N     1 
ATOM   15459 C CA    . ARG E 1 300 ? -53.409  -8.882   -49.292 1.00 23.17  ? 300  ARG E CA    1 
ATOM   15460 C C     . ARG E 1 300 ? -54.465  -8.420   -50.284 1.00 24.39  ? 300  ARG E C     1 
ATOM   15461 O O     . ARG E 1 300 ? -54.201  -8.431   -51.487 1.00 28.11  ? 300  ARG E O     1 
ATOM   15462 C CB    . ARG E 1 300 ? -53.666  -10.335  -48.893 1.00 25.03  ? 300  ARG E CB    1 
ATOM   15463 C CG    . ARG E 1 300 ? -52.459  -10.949  -48.214 1.00 27.17  ? 300  ARG E CG    1 
ATOM   15464 C CD    . ARG E 1 300 ? -52.899  -12.208  -47.533 1.00 28.03  ? 300  ARG E CD    1 
ATOM   15465 N NE    . ARG E 1 300 ? -51.725  -12.792  -46.870 1.00 33.22  ? 300  ARG E NE    1 
ATOM   15466 C CZ    . ARG E 1 300 ? -50.745  -13.445  -47.513 1.00 32.56  ? 300  ARG E CZ    1 
ATOM   15467 N NH1   . ARG E 1 300 ? -50.847  -13.735  -48.815 1.00 24.24  ? 300  ARG E NH1   1 
ATOM   15468 N NH2   . ARG E 1 300 ? -49.727  -13.889  -46.788 1.00 31.63  ? 300  ARG E NH2   1 
ATOM   15469 N N     . TRP E 1 301 ? -55.633  -7.988   -49.777 1.00 22.65  ? 301  TRP E N     1 
ATOM   15470 C CA    . TRP E 1 301 ? -56.688  -7.569   -50.680 1.00 22.78  ? 301  TRP E CA    1 
ATOM   15471 C C     . TRP E 1 301 ? -56.310  -6.271   -51.406 1.00 23.46  ? 301  TRP E C     1 
ATOM   15472 O O     . TRP E 1 301 ? -56.527  -6.154   -52.613 1.00 27.72  ? 301  TRP E O     1 
ATOM   15473 C CB    . TRP E 1 301 ? -58.035  -7.453   -49.953 1.00 18.37  ? 301  TRP E CB    1 
ATOM   15474 C CG    . TRP E 1 301 ? -59.170  -7.194   -50.899 1.00 19.95  ? 301  TRP E CG    1 
ATOM   15475 C CD1   . TRP E 1 301 ? -59.879  -8.142   -51.580 1.00 18.46  ? 301  TRP E CD1   1 
ATOM   15476 C CD2   . TRP E 1 301 ? -59.711  -5.913   -51.296 1.00 22.01  ? 301  TRP E CD2   1 
ATOM   15477 N NE1   . TRP E 1 301 ? -60.832  -7.546   -52.353 1.00 19.72  ? 301  TRP E NE1   1 
ATOM   15478 C CE2   . TRP E 1 301 ? -60.754  -6.182   -52.219 1.00 21.93  ? 301  TRP E CE2   1 
ATOM   15479 C CE3   . TRP E 1 301 ? -59.420  -4.577   -50.988 1.00 24.21  ? 301  TRP E CE3   1 
ATOM   15480 C CZ2   . TRP E 1 301 ? -61.501  -5.167   -52.830 1.00 23.10  ? 301  TRP E CZ2   1 
ATOM   15481 C CZ3   . TRP E 1 301 ? -60.157  -3.574   -51.593 1.00 24.80  ? 301  TRP E CZ3   1 
ATOM   15482 C CH2   . TRP E 1 301 ? -61.180  -3.865   -52.509 1.00 23.60  ? 301  TRP E CH2   1 
ATOM   15483 N N     . THR E 1 302 ? -55.783  -5.279   -50.678 1.00 21.11  ? 302  THR E N     1 
ATOM   15484 C CA    . THR E 1 302 ? -55.579  -3.975   -51.294 1.00 20.12  ? 302  THR E CA    1 
ATOM   15485 C C     . THR E 1 302 ? -54.426  -4.062   -52.296 1.00 21.40  ? 302  THR E C     1 
ATOM   15486 O O     . THR E 1 302 ? -54.446  -3.370   -53.296 1.00 25.29  ? 302  THR E O     1 
ATOM   15487 C CB    . THR E 1 302 ? -55.362  -2.855   -50.277 1.00 19.54  ? 302  THR E CB    1 
ATOM   15488 O OG1   . THR E 1 302 ? -54.160  -3.237   -49.617 1.00 22.32  ? 302  THR E OG1   1 
ATOM   15489 C CG2   . THR E 1 302 ? -56.504  -2.674   -49.297 1.00 17.76  ? 302  THR E CG2   1 
ATOM   15490 N N     . ALA E 1 303 ? -53.427  -4.921   -52.052 1.00 23.01  ? 303  ALA E N     1 
ATOM   15491 C CA    . ALA E 1 303 ? -52.376  -5.121   -53.051 1.00 23.09  ? 303  ALA E CA    1 
ATOM   15492 C C     . ALA E 1 303 ? -52.980  -5.653   -54.358 1.00 28.09  ? 303  ALA E C     1 
ATOM   15493 O O     . ALA E 1 303 ? -52.643  -5.174   -55.436 1.00 30.04  ? 303  ALA E O     1 
ATOM   15494 C CB    . ALA E 1 303 ? -51.235  -5.990   -52.532 1.00 17.38  ? 303  ALA E CB    1 
ATOM   15495 N N     . MET E 1 304 ? -53.905  -6.619   -54.262 1.00 26.75  ? 304  MET E N     1 
ATOM   15496 C CA    . MET E 1 304 ? -54.560  -7.157   -55.448 1.00 27.17  ? 304  MET E CA    1 
ATOM   15497 C C     . MET E 1 304 ? -55.394  -6.054   -56.111 1.00 26.85  ? 304  MET E C     1 
ATOM   15498 O O     . MET E 1 304 ? -55.421  -5.963   -57.330 1.00 26.05  ? 304  MET E O     1 
ATOM   15499 C CB    . MET E 1 304 ? -55.358  -8.419   -55.076 1.00 26.33  ? 304  MET E CB    1 
ATOM   15500 C CG    . MET E 1 304 ? -56.305  -8.990   -56.146 1.00 24.38  ? 304  MET E CG    1 
ATOM   15501 S SD    . MET E 1 304 ? -57.833  -8.060   -56.422 1.00 27.30  ? 304  MET E SD    1 
ATOM   15502 C CE    . MET E 1 304 ? -58.752  -8.338   -54.905 1.00 24.81  ? 304  MET E CE    1 
ATOM   15503 N N     . ALA E 1 305 ? -56.069  -5.209   -55.312 1.00 24.72  ? 305  ALA E N     1 
ATOM   15504 C CA    . ALA E 1 305 ? -57.049  -4.249   -55.829 1.00 24.75  ? 305  ALA E CA    1 
ATOM   15505 C C     . ALA E 1 305 ? -56.407  -2.921   -56.250 1.00 26.68  ? 305  ALA E C     1 
ATOM   15506 O O     . ALA E 1 305 ? -57.133  -2.030   -56.703 1.00 26.50  ? 305  ALA E O     1 
ATOM   15507 C CB    . ALA E 1 305 ? -58.135  -3.988   -54.806 1.00 22.86  ? 305  ALA E CB    1 
ATOM   15508 N N     . ALA E 1 306 ? -55.071  -2.784   -56.101 1.00 25.18  ? 306  ALA E N     1 
ATOM   15509 C CA    . ALA E 1 306 ? -54.333  -1.542   -56.370 1.00 26.05  ? 306  ALA E CA    1 
ATOM   15510 C C     . ALA E 1 306 ? -54.716  -0.869   -57.695 1.00 28.66  ? 306  ALA E C     1 
ATOM   15511 O O     . ALA E 1 306 ? -54.777  0.361    -57.753 1.00 29.87  ? 306  ALA E O     1 
ATOM   15512 C CB    . ALA E 1 306 ? -52.819  -1.768   -56.295 1.00 22.59  ? 306  ALA E CB    1 
ATOM   15513 N N     . PRO E 1 307 ? -54.941  -1.587   -58.836 1.00 26.33  ? 307  PRO E N     1 
ATOM   15514 C CA    . PRO E 1 307 ? -55.286  -0.897   -60.071 1.00 26.66  ? 307  PRO E CA    1 
ATOM   15515 C C     . PRO E 1 307 ? -56.556  -0.051   -59.976 1.00 28.82  ? 307  PRO E C     1 
ATOM   15516 O O     . PRO E 1 307 ? -56.730  0.847    -60.781 1.00 28.94  ? 307  PRO E O     1 
ATOM   15517 C CB    . PRO E 1 307 ? -55.365  -1.992   -61.134 1.00 23.79  ? 307  PRO E CB    1 
ATOM   15518 C CG    . PRO E 1 307 ? -54.542  -3.111   -60.546 1.00 22.59  ? 307  PRO E CG    1 
ATOM   15519 C CD    . PRO E 1 307 ? -54.749  -3.027   -59.041 1.00 23.14  ? 307  PRO E CD    1 
ATOM   15520 N N     . VAL E 1 308 ? -57.444  -0.322   -59.005 1.00 27.36  ? 308  VAL E N     1 
ATOM   15521 C CA    . VAL E 1 308 ? -58.727  0.368    -58.985 1.00 25.34  ? 308  VAL E CA    1 
ATOM   15522 C C     . VAL E 1 308 ? -58.990  1.076    -57.651 1.00 24.90  ? 308  VAL E C     1 
ATOM   15523 O O     . VAL E 1 308 ? -59.800  1.996    -57.590 1.00 28.91  ? 308  VAL E O     1 
ATOM   15524 C CB    . VAL E 1 308 ? -59.893  -0.570   -59.378 1.00 26.29  ? 308  VAL E CB    1 
ATOM   15525 C CG1   . VAL E 1 308 ? -60.118  -1.673   -58.341 1.00 22.44  ? 308  VAL E CG1   1 
ATOM   15526 C CG2   . VAL E 1 308 ? -61.174  0.210    -59.581 1.00 20.55  ? 308  VAL E CG2   1 
ATOM   15527 N N     . LEU E 1 309 ? -58.333  0.647    -56.570 1.00 26.58  ? 309  LEU E N     1 
ATOM   15528 C CA    . LEU E 1 309 ? -58.687  1.140    -55.244 1.00 26.16  ? 309  LEU E CA    1 
ATOM   15529 C C     . LEU E 1 309 ? -58.550  2.665    -55.143 1.00 28.08  ? 309  LEU E C     1 
ATOM   15530 O O     . LEU E 1 309 ? -59.351  3.301    -54.472 1.00 33.49  ? 309  LEU E O     1 
ATOM   15531 C CB    . LEU E 1 309 ? -57.820  0.451    -54.200 1.00 25.80  ? 309  LEU E CB    1 
ATOM   15532 C CG    . LEU E 1 309 ? -58.070  0.873    -52.744 1.00 24.07  ? 309  LEU E CG    1 
ATOM   15533 C CD1   . LEU E 1 309 ? -59.492  0.562    -52.304 1.00 22.57  ? 309  LEU E CD1   1 
ATOM   15534 C CD2   . LEU E 1 309 ? -57.049  0.159    -51.866 1.00 22.98  ? 309  LEU E CD2   1 
ATOM   15535 N N     . TYR E 1 310 ? -57.514  3.247    -55.759 1.00 25.61  ? 310  TYR E N     1 
ATOM   15536 C CA    . TYR E 1 310 ? -57.192  4.669    -55.647 1.00 26.38  ? 310  TYR E CA    1 
ATOM   15537 C C     . TYR E 1 310 ? -57.946  5.519    -56.673 1.00 29.11  ? 310  TYR E C     1 
ATOM   15538 O O     . TYR E 1 310 ? -58.604  6.498    -56.301 1.00 31.07  ? 310  TYR E O     1 
ATOM   15539 C CB    . TYR E 1 310 ? -55.671  4.875    -55.703 1.00 26.67  ? 310  TYR E CB    1 
ATOM   15540 C CG    . TYR E 1 310 ? -55.033  3.974    -54.662 1.00 26.83  ? 310  TYR E CG    1 
ATOM   15541 C CD1   . TYR E 1 310 ? -55.252  4.202    -53.296 1.00 24.78  ? 310  TYR E CD1   1 
ATOM   15542 C CD2   . TYR E 1 310 ? -54.313  2.847    -55.046 1.00 26.14  ? 310  TYR E CD2   1 
ATOM   15543 C CE1   . TYR E 1 310 ? -54.748  3.323    -52.348 1.00 28.42  ? 310  TYR E CE1   1 
ATOM   15544 C CE2   . TYR E 1 310 ? -53.786  1.972    -54.099 1.00 28.33  ? 310  TYR E CE2   1 
ATOM   15545 C CZ    . TYR E 1 310 ? -54.002  2.217    -52.746 1.00 31.33  ? 310  TYR E CZ    1 
ATOM   15546 O OH    . TYR E 1 310 ? -53.493  1.367    -51.798 1.00 29.44  ? 310  TYR E OH    1 
ATOM   15547 N N     . LYS E 1 311 ? -57.893  5.127    -57.957 1.00 29.80  ? 311  LYS E N     1 
ATOM   15548 C CA    . LYS E 1 311 ? -58.433  5.956    -59.031 1.00 30.48  ? 311  LYS E CA    1 
ATOM   15549 C C     . LYS E 1 311 ? -59.874  5.602    -59.378 1.00 30.48  ? 311  LYS E C     1 
ATOM   15550 O O     . LYS E 1 311 ? -60.511  6.376    -60.070 1.00 27.43  ? 311  LYS E O     1 
ATOM   15551 C CB    . LYS E 1 311 ? -57.574  5.751    -60.279 1.00 29.64  ? 311  LYS E CB    1 
ATOM   15552 C CG    . LYS E 1 311 ? -56.121  6.213    -60.097 1.00 34.28  ? 311  LYS E CG    1 
ATOM   15553 C CD    . LYS E 1 311 ? -56.075  7.732    -59.997 1.00 40.39  ? 311  LYS E CD    1 
ATOM   15554 C CE    . LYS E 1 311 ? -54.703  8.293    -60.099 1.00 47.47  ? 311  LYS E CE    1 
ATOM   15555 N NZ    . LYS E 1 311 ? -54.834  9.754    -60.107 1.00 43.66  ? 311  LYS E NZ    1 
ATOM   15556 N N     . GLY E 1 312 ? -60.386  4.439    -58.926 1.00 30.01  ? 312  GLY E N     1 
ATOM   15557 C CA    . GLY E 1 312 ? -61.720  4.003    -59.316 1.00 26.40  ? 312  GLY E CA    1 
ATOM   15558 C C     . GLY E 1 312 ? -62.798  4.917    -58.752 1.00 26.87  ? 312  GLY E C     1 
ATOM   15559 O O     . GLY E 1 312 ? -62.714  5.361    -57.612 1.00 28.76  ? 312  GLY E O     1 
ATOM   15560 N N     . ARG E 1 313 ? -63.824  5.195    -59.568 1.00 27.67  ? 313  ARG E N     1 
ATOM   15561 C CA    . ARG E 1 313 ? -64.895  6.098    -59.177 1.00 25.78  ? 313  ARG E CA    1 
ATOM   15562 C C     . ARG E 1 313 ? -66.234  5.452    -59.510 1.00 28.24  ? 313  ARG E C     1 
ATOM   15563 O O     . ARG E 1 313 ? -66.325  4.657    -60.451 1.00 29.59  ? 313  ARG E O     1 
ATOM   15564 C CB    . ARG E 1 313 ? -64.795  7.443    -59.915 1.00 24.69  ? 313  ARG E CB    1 
ATOM   15565 C CG    . ARG E 1 313 ? -63.556  8.256    -59.529 1.00 24.55  ? 313  ARG E CG    1 
ATOM   15566 C CD    . ARG E 1 313 ? -63.637  8.727    -58.073 1.00 24.52  ? 313  ARG E CD    1 
ATOM   15567 N NE    . ARG E 1 313 ? -62.454  9.527    -57.735 1.00 27.24  ? 313  ARG E NE    1 
ATOM   15568 C CZ    . ARG E 1 313 ? -61.281  9.079    -57.278 1.00 35.24  ? 313  ARG E CZ    1 
ATOM   15569 N NH1   . ARG E 1 313 ? -61.050  7.775    -57.094 1.00 33.36  ? 313  ARG E NH1   1 
ATOM   15570 N NH2   . ARG E 1 313 ? -60.316  9.956    -57.037 1.00 31.14  ? 313  ARG E NH2   1 
ATOM   15571 N N     . PRO E 1 314 ? -67.307  5.797    -58.778 1.00 25.26  ? 314  PRO E N     1 
ATOM   15572 C CA    . PRO E 1 314 ? -68.638  5.307    -59.116 1.00 28.34  ? 314  PRO E CA    1 
ATOM   15573 C C     . PRO E 1 314 ? -69.033  5.715    -60.523 1.00 30.46  ? 314  PRO E C     1 
ATOM   15574 O O     . PRO E 1 314 ? -68.577  6.749    -61.012 1.00 34.47  ? 314  PRO E O     1 
ATOM   15575 C CB    . PRO E 1 314 ? -69.581  6.023    -58.137 1.00 26.36  ? 314  PRO E CB    1 
ATOM   15576 C CG    . PRO E 1 314 ? -68.658  6.528    -57.038 1.00 26.47  ? 314  PRO E CG    1 
ATOM   15577 C CD    . PRO E 1 314 ? -67.292  6.735    -57.642 1.00 26.18  ? 314  PRO E CD    1 
ATOM   15578 N N     . VAL E 1 315 ? -69.913  4.931    -61.155 1.00 34.94  ? 315  VAL E N     1 
ATOM   15579 C CA    . VAL E 1 315 ? -70.304  5.224    -62.526 1.00 36.12  ? 315  VAL E CA    1 
ATOM   15580 C C     . VAL E 1 315 ? -71.734  4.740    -62.668 1.00 35.49  ? 315  VAL E C     1 
ATOM   15581 O O     . VAL E 1 315 ? -72.121  3.852    -61.934 1.00 31.91  ? 315  VAL E O     1 
ATOM   15582 C CB    . VAL E 1 315 ? -69.261  4.461    -63.375 1.00 41.20  ? 315  VAL E CB    1 
ATOM   15583 C CG1   . VAL E 1 315 ? -69.380  2.947    -63.288 1.00 34.50  ? 315  VAL E CG1   1 
ATOM   15584 C CG2   . VAL E 1 315 ? -69.172  4.956    -64.804 1.00 41.78  ? 315  VAL E CG2   1 
ATOM   15585 N N     . PRO E 1 316 ? -72.596  5.330    -63.531 1.00 42.69  ? 316  PRO E N     1 
ATOM   15586 C CA    . PRO E 1 316 ? -73.990  4.876    -63.623 1.00 44.24  ? 316  PRO E CA    1 
ATOM   15587 C C     . PRO E 1 316 ? -74.139  3.521    -64.339 1.00 43.44  ? 316  PRO E C     1 
ATOM   15588 O O     . PRO E 1 316 ? -74.613  3.445    -65.461 1.00 42.02  ? 316  PRO E O     1 
ATOM   15589 C CB    . PRO E 1 316 ? -74.693  6.075    -64.283 1.00 40.82  ? 316  PRO E CB    1 
ATOM   15590 C CG    . PRO E 1 316 ? -73.591  6.612    -65.208 1.00 35.88  ? 316  PRO E CG    1 
ATOM   15591 C CD    . PRO E 1 316 ? -72.276  6.406    -64.495 1.00 37.07  ? 316  PRO E CD    1 
ATOM   15592 N N     . VAL E 1 317 ? -73.637  2.451    -63.715 1.00 41.10  ? 317  VAL E N     1 
ATOM   15593 C CA    . VAL E 1 317 ? -73.725  1.104    -64.247 1.00 36.63  ? 317  VAL E CA    1 
ATOM   15594 C C     . VAL E 1 317 ? -74.285  0.263    -63.112 1.00 38.93  ? 317  VAL E C     1 
ATOM   15595 O O     . VAL E 1 317 ? -73.717  0.274    -62.029 1.00 39.89  ? 317  VAL E O     1 
ATOM   15596 C CB    . VAL E 1 317 ? -72.373  0.536    -64.713 1.00 32.19  ? 317  VAL E CB    1 
ATOM   15597 C CG1   . VAL E 1 317 ? -72.508  -0.907   -65.184 1.00 28.41  ? 317  VAL E CG1   1 
ATOM   15598 C CG2   . VAL E 1 317 ? -71.758  1.378    -65.831 1.00 31.11  ? 317  VAL E CG2   1 
ATOM   15599 N N     . THR E 1 318 ? -75.415  -0.410   -63.323 1.00 32.99  ? 318  THR E N     1 
ATOM   15600 C CA    . THR E 1 318 ? -75.994  -1.170   -62.230 1.00 33.68  ? 318  THR E CA    1 
ATOM   15601 C C     . THR E 1 318 ? -75.794  -2.672   -62.445 1.00 34.76  ? 318  THR E C     1 
ATOM   15602 O O     . THR E 1 318 ? -75.502  -3.134   -63.550 1.00 33.37  ? 318  THR E O     1 
ATOM   15603 C CB    . THR E 1 318 ? -77.455  -0.788   -61.994 1.00 36.51  ? 318  THR E CB    1 
ATOM   15604 O OG1   . THR E 1 318 ? -78.147  -1.146   -63.180 1.00 36.67  ? 318  THR E OG1   1 
ATOM   15605 C CG2   . THR E 1 318 ? -77.649  0.689    -61.715 1.00 38.12  ? 318  THR E CG2   1 
ATOM   15606 N N     . SER E 1 319 ? -75.973  -3.434   -61.364 1.00 32.47  ? 319  SER E N     1 
ATOM   15607 C CA    . SER E 1 319 ? -75.864  -4.876   -61.465 1.00 32.00  ? 319  SER E CA    1 
ATOM   15608 C C     . SER E 1 319 ? -77.268  -5.467   -61.588 1.00 27.50  ? 319  SER E C     1 
ATOM   15609 O O     . SER E 1 319 ? -78.242  -4.839   -61.233 1.00 27.25  ? 319  SER E O     1 
ATOM   15610 C CB    . SER E 1 319 ? -75.080  -5.436   -60.314 1.00 31.39  ? 319  SER E CB    1 
ATOM   15611 O OG    . SER E 1 319 ? -75.846  -5.365   -59.114 1.00 39.43  ? 319  SER E OG    1 
ATOM   15612 N N     . ALA E 1 320 ? -77.370  -6.672   -62.122 1.00 30.68  ? 320  ALA E N     1 
ATOM   15613 C CA    . ALA E 1 320 ? -78.627  -7.394   -62.266 1.00 30.64  ? 320  ALA E CA    1 
ATOM   15614 C C     . ALA E 1 320 ? -79.302  -7.635   -60.910 1.00 32.32  ? 320  ALA E C     1 
ATOM   15615 O O     . ALA E 1 320 ? -78.657  -7.647   -59.855 1.00 28.63  ? 320  ALA E O     1 
ATOM   15616 C CB    . ALA E 1 320 ? -78.329  -8.745   -62.899 1.00 31.15  ? 320  ALA E CB    1 
ATOM   15617 N N     . HIS E 1 321 ? -80.619  -7.887   -60.976 1.00 30.86  ? 321  HIS E N     1 
ATOM   15618 C CA    . HIS E 1 321 ? -81.462  -8.239   -59.853 1.00 27.92  ? 321  HIS E CA    1 
ATOM   15619 C C     . HIS E 1 321 ? -80.810  -9.317   -58.985 1.00 30.92  ? 321  HIS E C     1 
ATOM   15620 O O     . HIS E 1 321 ? -80.406  -10.358  -59.490 1.00 25.21  ? 321  HIS E O     1 
ATOM   15621 C CB    . HIS E 1 321 ? -82.855  -8.622   -60.345 1.00 28.50  ? 321  HIS E CB    1 
ATOM   15622 C CG    . HIS E 1 321 ? -83.752  -9.022   -59.232 1.00 34.38  ? 321  HIS E CG    1 
ATOM   15623 N ND1   . HIS E 1 321 ? -84.052  -10.354  -59.027 1.00 40.84  ? 321  HIS E ND1   1 
ATOM   15624 C CD2   . HIS E 1 321 ? -84.444  -8.330   -58.293 1.00 32.29  ? 321  HIS E CD2   1 
ATOM   15625 C CE1   . HIS E 1 321 ? -84.855  -10.487  -57.971 1.00 33.02  ? 321  HIS E CE1   1 
ATOM   15626 N NE2   . HIS E 1 321 ? -85.084  -9.263   -57.519 1.00 34.92  ? 321  HIS E NE2   1 
ATOM   15627 N N     . GLY E 1 322 ? -80.724  -9.040   -57.672 1.00 33.99  ? 322  GLY E N     1 
ATOM   15628 C CA    . GLY E 1 322 ? -80.369  -10.059  -56.693 1.00 34.13  ? 322  GLY E CA    1 
ATOM   15629 C C     . GLY E 1 322 ? -78.865  -10.245  -56.483 1.00 37.69  ? 322  GLY E C     1 
ATOM   15630 O O     . GLY E 1 322 ? -78.469  -11.211  -55.841 1.00 40.87  ? 322  GLY E O     1 
ATOM   15631 N N     . THR E 1 323 ? -78.017  -9.348   -57.022 1.00 30.41  ? 323  THR E N     1 
ATOM   15632 C CA    . THR E 1 323 ? -76.591  -9.430   -56.768 1.00 26.29  ? 323  THR E CA    1 
ATOM   15633 C C     . THR E 1 323 ? -76.176  -8.143   -56.076 1.00 27.06  ? 323  THR E C     1 
ATOM   15634 O O     . THR E 1 323 ? -76.907  -7.181   -56.116 1.00 30.14  ? 323  THR E O     1 
ATOM   15635 C CB    . THR E 1 323 ? -75.790  -9.687   -58.049 1.00 30.37  ? 323  THR E CB    1 
ATOM   15636 O OG1   . THR E 1 323 ? -75.618  -8.442   -58.731 1.00 29.29  ? 323  THR E OG1   1 
ATOM   15637 C CG2   . THR E 1 323 ? -76.425  -10.730  -58.969 1.00 23.47  ? 323  THR E CG2   1 
ATOM   15638 N N     . ARG E 1 324 ? -75.005  -8.141   -55.457 1.00 29.88  ? 324  ARG E N     1 
ATOM   15639 C CA    . ARG E 1 324 ? -74.453  -6.978   -54.788 1.00 29.84  ? 324  ARG E CA    1 
ATOM   15640 C C     . ARG E 1 324 ? -73.255  -6.473   -55.594 1.00 28.32  ? 324  ARG E C     1 
ATOM   15641 O O     . ARG E 1 324 ? -72.453  -5.692   -55.078 1.00 32.00  ? 324  ARG E O     1 
ATOM   15642 C CB    . ARG E 1 324 ? -73.947  -7.404   -53.396 1.00 27.65  ? 324  ARG E CB    1 
ATOM   15643 C CG    . ARG E 1 324 ? -75.054  -7.980   -52.520 1.00 31.73  ? 324  ARG E CG    1 
ATOM   15644 C CD    . ARG E 1 324 ? -74.716  -8.251   -51.064 1.00 29.22  ? 324  ARG E CD    1 
ATOM   15645 N NE    . ARG E 1 324 ? -73.650  -9.247   -50.901 1.00 27.89  ? 324  ARG E NE    1 
ATOM   15646 C CZ    . ARG E 1 324 ? -72.651  -9.206   -50.028 1.00 28.54  ? 324  ARG E CZ    1 
ATOM   15647 N NH1   . ARG E 1 324 ? -72.437  -8.126   -49.308 1.00 27.26  ? 324  ARG E NH1   1 
ATOM   15648 N NH2   . ARG E 1 324 ? -71.834  -10.239  -49.886 1.00 25.97  ? 324  ARG E NH2   1 
ATOM   15649 N N     . ASP E 1 325 ? -73.096  -6.954   -56.830 1.00 21.38  ? 325  ASP E N     1 
ATOM   15650 C CA    . ASP E 1 325 ? -71.940  -6.580   -57.649 1.00 24.86  ? 325  ASP E CA    1 
ATOM   15651 C C     . ASP E 1 325 ? -72.014  -5.086   -58.000 1.00 24.78  ? 325  ASP E C     1 
ATOM   15652 O O     . ASP E 1 325 ? -73.109  -4.509   -58.015 1.00 24.24  ? 325  ASP E O     1 
ATOM   15653 C CB    . ASP E 1 325 ? -71.886  -7.479   -58.876 1.00 23.39  ? 325  ASP E CB    1 
ATOM   15654 C CG    . ASP E 1 325 ? -71.921  -8.981   -58.569 1.00 29.63  ? 325  ASP E CG    1 
ATOM   15655 O OD1   . ASP E 1 325 ? -71.526  -9.394   -57.418 1.00 28.12  ? 325  ASP E OD1   1 
ATOM   15656 O OD2   . ASP E 1 325 ? -72.355  -9.749   -59.473 1.00 26.13  ? 325  ASP E OD2   1 
ATOM   15657 N N     . PHE E 1 326 ? -70.871  -4.459   -58.311 1.00 23.34  ? 326  PHE E N     1 
ATOM   15658 C CA    . PHE E 1 326 ? -70.895  -3.062   -58.727 1.00 22.60  ? 326  PHE E CA    1 
ATOM   15659 C C     . PHE E 1 326 ? -69.685  -2.791   -59.627 1.00 26.80  ? 326  PHE E C     1 
ATOM   15660 O O     . PHE E 1 326 ? -68.801  -3.657   -59.771 1.00 25.56  ? 326  PHE E O     1 
ATOM   15661 C CB    . PHE E 1 326 ? -70.935  -2.118   -57.515 1.00 20.24  ? 326  PHE E CB    1 
ATOM   15662 C CG    . PHE E 1 326 ? -69.716  -2.220   -56.601 1.00 21.80  ? 326  PHE E CG    1 
ATOM   15663 C CD1   . PHE E 1 326 ? -68.570  -1.450   -56.821 1.00 22.85  ? 326  PHE E CD1   1 
ATOM   15664 C CD2   . PHE E 1 326 ? -69.708  -3.083   -55.499 1.00 20.76  ? 326  PHE E CD2   1 
ATOM   15665 C CE1   . PHE E 1 326 ? -67.468  -1.529   -55.959 1.00 23.40  ? 326  PHE E CE1   1 
ATOM   15666 C CE2   . PHE E 1 326 ? -68.610  -3.170   -54.639 1.00 19.07  ? 326  PHE E CE2   1 
ATOM   15667 C CZ    . PHE E 1 326 ? -67.486  -2.393   -54.880 1.00 21.61  ? 326  PHE E CZ    1 
ATOM   15668 N N     . VAL E 1 327 ? -69.641  -1.572   -60.209 1.00 25.71  ? 327  VAL E N     1 
ATOM   15669 C CA    . VAL E 1 327 ? -68.593  -1.224   -61.167 1.00 26.15  ? 327  VAL E CA    1 
ATOM   15670 C C     . VAL E 1 327 ? -67.852  0.042    -60.728 1.00 27.01  ? 327  VAL E C     1 
ATOM   15671 O O     . VAL E 1 327 ? -68.451  0.959    -60.194 1.00 30.66  ? 327  VAL E O     1 
ATOM   15672 C CB    . VAL E 1 327 ? -69.263  -1.012   -62.537 1.00 27.37  ? 327  VAL E CB    1 
ATOM   15673 C CG1   . VAL E 1 327 ? -68.226  -0.691   -63.622 1.00 21.79  ? 327  VAL E CG1   1 
ATOM   15674 C CG2   . VAL E 1 327 ? -70.150  -2.205   -62.898 1.00 24.29  ? 327  VAL E CG2   1 
ATOM   15675 N N     . LEU E 1 328 ? -66.539  0.080    -60.946 1.00 28.72  ? 328  LEU E N     1 
ATOM   15676 C CA    . LEU E 1 328 ? -65.723  1.263    -60.717 1.00 28.10  ? 328  LEU E CA    1 
ATOM   15677 C C     . LEU E 1 328 ? -65.049  1.641    -62.039 1.00 28.99  ? 328  LEU E C     1 
ATOM   15678 O O     . LEU E 1 328 ? -64.604  0.781    -62.806 1.00 29.87  ? 328  LEU E O     1 
ATOM   15679 C CB    . LEU E 1 328 ? -64.692  1.031    -59.600 1.00 23.05  ? 328  LEU E CB    1 
ATOM   15680 C CG    . LEU E 1 328 ? -65.261  0.810    -58.196 1.00 22.49  ? 328  LEU E CG    1 
ATOM   15681 C CD1   . LEU E 1 328 ? -64.183  0.356    -57.184 1.00 19.51  ? 328  LEU E CD1   1 
ATOM   15682 C CD2   . LEU E 1 328 ? -65.979  2.099    -57.742 1.00 18.39  ? 328  LEU E CD2   1 
ATOM   15683 N N     . HIS E 1 329 ? -64.961  2.952    -62.281 1.00 30.74  ? 329  HIS E N     1 
ATOM   15684 C CA    . HIS E 1 329 ? -64.425  3.507    -63.514 1.00 30.77  ? 329  HIS E CA    1 
ATOM   15685 C C     . HIS E 1 329 ? -63.097  4.207    -63.244 1.00 30.64  ? 329  HIS E C     1 
ATOM   15686 O O     . HIS E 1 329 ? -62.980  4.982    -62.292 1.00 32.59  ? 329  HIS E O     1 
ATOM   15687 C CB    . HIS E 1 329 ? -65.480  4.464    -64.087 1.00 35.02  ? 329  HIS E CB    1 
ATOM   15688 C CG    . HIS E 1 329 ? -65.016  5.245    -65.269 1.00 43.17  ? 329  HIS E CG    1 
ATOM   15689 N ND1   . HIS E 1 329 ? -64.968  4.714    -66.542 1.00 43.78  ? 329  HIS E ND1   1 
ATOM   15690 C CD2   . HIS E 1 329 ? -64.567  6.502    -65.373 1.00 42.75  ? 329  HIS E CD2   1 
ATOM   15691 C CE1   . HIS E 1 329 ? -64.503  5.623    -67.381 1.00 41.52  ? 329  HIS E CE1   1 
ATOM   15692 N NE2   . HIS E 1 329 ? -64.251  6.708    -66.694 1.00 48.43  ? 329  HIS E NE2   1 
ATOM   15693 N N     . THR E 1 330 ? -62.074  3.892    -64.043 1.00 32.71  ? 330  THR E N     1 
ATOM   15694 C CA    . THR E 1 330 ? -60.909  4.759    -64.147 1.00 34.88  ? 330  THR E CA    1 
ATOM   15695 C C     . THR E 1 330 ? -60.885  5.296    -65.581 1.00 41.75  ? 330  THR E C     1 
ATOM   15696 O O     . THR E 1 330 ? -61.734  4.940    -66.387 1.00 47.02  ? 330  THR E O     1 
ATOM   15697 C CB    . THR E 1 330 ? -59.613  4.048    -63.782 1.00 32.93  ? 330  THR E CB    1 
ATOM   15698 O OG1   . THR E 1 330 ? -59.379  3.122    -64.846 1.00 35.75  ? 330  THR E OG1   1 
ATOM   15699 C CG2   . THR E 1 330 ? -59.673  3.408    -62.411 1.00 31.89  ? 330  THR E CG2   1 
ATOM   15700 N N     . SER E 1 331 ? -59.928  6.162    -65.913 1.00 48.05  ? 331  SER E N     1 
ATOM   15701 C CA    . SER E 1 331 ? -59.985  6.745    -67.242 1.00 53.78  ? 331  SER E CA    1 
ATOM   15702 C C     . SER E 1 331 ? -59.638  5.707    -68.315 1.00 50.21  ? 331  SER E C     1 
ATOM   15703 O O     . SER E 1 331 ? -60.100  5.853    -69.429 1.00 45.72  ? 331  SER E O     1 
ATOM   15704 C CB    . SER E 1 331 ? -59.134  7.988    -67.360 1.00 53.27  ? 331  SER E CB    1 
ATOM   15705 O OG    . SER E 1 331 ? -57.793  7.611    -67.081 1.00 49.46  ? 331  SER E OG    1 
ATOM   15706 N N     . LYS E 1 332 ? -58.894  4.644    -67.978 1.00 55.00  ? 332  LYS E N     1 
ATOM   15707 C CA    . LYS E 1 332 ? -58.507  3.644    -68.966 1.00 59.98  ? 332  LYS E CA    1 
ATOM   15708 C C     . LYS E 1 332 ? -59.363  2.373    -68.930 1.00 58.02  ? 332  LYS E C     1 
ATOM   15709 O O     . LYS E 1 332 ? -59.411  1.647    -69.926 1.00 48.44  ? 332  LYS E O     1 
ATOM   15710 C CB    . LYS E 1 332 ? -57.012  3.328    -68.856 1.00 71.32  ? 332  LYS E CB    1 
ATOM   15711 C CG    . LYS E 1 332 ? -56.146  4.312    -69.601 1.00 83.14  ? 332  LYS E CG    1 
ATOM   15712 C CD    . LYS E 1 332 ? -54.697  4.333    -69.123 1.00 89.85  ? 332  LYS E CD    1 
ATOM   15713 C CE    . LYS E 1 332 ? -54.766  4.499    -67.629 1.00 92.66  ? 332  LYS E CE    1 
ATOM   15714 N NZ    . LYS E 1 332 ? -53.491  4.942    -67.080 1.00 82.23  ? 332  LYS E NZ    1 
ATOM   15715 N N     . HIS E 1 333 ? -60.050  2.075    -67.808 1.00 50.93  ? 333  HIS E N     1 
ATOM   15716 C CA    . HIS E 1 333 ? -60.712  0.789    -67.662 1.00 37.60  ? 333  HIS E CA    1 
ATOM   15717 C C     . HIS E 1 333 ? -61.967  0.898    -66.804 1.00 38.29  ? 333  HIS E C     1 
ATOM   15718 O O     . HIS E 1 333 ? -62.120  1.825    -66.007 1.00 40.27  ? 333  HIS E O     1 
ATOM   15719 C CB    . HIS E 1 333 ? -59.778  -0.224   -66.999 1.00 35.92  ? 333  HIS E CB    1 
ATOM   15720 C CG    . HIS E 1 333 ? -58.507  -0.499   -67.742 1.00 37.62  ? 333  HIS E CG    1 
ATOM   15721 N ND1   . HIS E 1 333 ? -58.448  -1.279   -68.884 1.00 37.23  ? 333  HIS E ND1   1 
ATOM   15722 C CD2   . HIS E 1 333 ? -57.247  -0.111   -67.497 1.00 37.06  ? 333  HIS E CD2   1 
ATOM   15723 C CE1   . HIS E 1 333 ? -57.190  -1.346   -69.312 1.00 39.06  ? 333  HIS E CE1   1 
ATOM   15724 N NE2   . HIS E 1 333 ? -56.440  -0.654   -68.476 1.00 40.45  ? 333  HIS E NE2   1 
ATOM   15725 N N     . ASP E 1 334 ? -62.879  -0.067   -66.977 1.00 34.08  ? 334  ASP E N     1 
ATOM   15726 C CA    . ASP E 1 334 ? -63.882  -0.324   -65.955 1.00 30.51  ? 334  ASP E CA    1 
ATOM   15727 C C     . ASP E 1 334 ? -63.496  -1.597   -65.201 1.00 30.49  ? 334  ASP E C     1 
ATOM   15728 O O     . ASP E 1 334 ? -62.778  -2.448   -65.736 1.00 25.43  ? 334  ASP E O     1 
ATOM   15729 C CB    . ASP E 1 334 ? -65.283  -0.321   -66.530 1.00 34.76  ? 334  ASP E CB    1 
ATOM   15730 C CG    . ASP E 1 334 ? -65.743  1.044    -67.020 1.00 43.18  ? 334  ASP E CG    1 
ATOM   15731 O OD1   . ASP E 1 334 ? -65.448  2.039    -66.332 1.00 48.36  ? 334  ASP E OD1   1 
ATOM   15732 O OD2   . ASP E 1 334 ? -66.377  1.111    -68.081 1.00 41.94  ? 334  ASP E OD2   1 
ATOM   15733 N N     . PHE E 1 335 ? -63.973  -1.702   -63.955 1.00 26.88  ? 335  PHE E N     1 
ATOM   15734 C CA    . PHE E 1 335 ? -63.680  -2.859   -63.120 1.00 24.98  ? 335  PHE E CA    1 
ATOM   15735 C C     . PHE E 1 335 ? -64.988  -3.362   -62.521 1.00 24.68  ? 335  PHE E C     1 
ATOM   15736 O O     . PHE E 1 335 ? -65.761  -2.567   -61.964 1.00 26.84  ? 335  PHE E O     1 
ATOM   15737 C CB    . PHE E 1 335 ? -62.693  -2.457   -62.020 1.00 22.79  ? 335  PHE E CB    1 
ATOM   15738 C CG    . PHE E 1 335 ? -61.320  -2.003   -62.510 1.00 23.00  ? 335  PHE E CG    1 
ATOM   15739 C CD1   . PHE E 1 335 ? -61.102  -0.696   -62.945 1.00 20.91  ? 335  PHE E CD1   1 
ATOM   15740 C CD2   . PHE E 1 335 ? -60.244  -2.887   -62.518 1.00 20.53  ? 335  PHE E CD2   1 
ATOM   15741 C CE1   . PHE E 1 335 ? -59.833  -0.304   -63.371 1.00 22.61  ? 335  PHE E CE1   1 
ATOM   15742 C CE2   . PHE E 1 335 ? -58.992  -2.479   -62.970 1.00 21.04  ? 335  PHE E CE2   1 
ATOM   15743 C CZ    . PHE E 1 335 ? -58.774  -1.193   -63.403 1.00 20.79  ? 335  PHE E CZ    1 
ATOM   15744 N N     . LEU E 1 336 ? -65.236  -4.665   -62.699 1.00 22.95  ? 336  LEU E N     1 
ATOM   15745 C CA    . LEU E 1 336 ? -66.373  -5.338   -62.087 1.00 26.27  ? 336  LEU E CA    1 
ATOM   15746 C C     . LEU E 1 336 ? -65.931  -5.867   -60.724 1.00 26.80  ? 336  LEU E C     1 
ATOM   15747 O O     . LEU E 1 336 ? -64.940  -6.601   -60.634 1.00 29.04  ? 336  LEU E O     1 
ATOM   15748 C CB    . LEU E 1 336 ? -66.856  -6.481   -62.986 1.00 26.05  ? 336  LEU E CB    1 
ATOM   15749 C CG    . LEU E 1 336 ? -67.112  -6.115   -64.453 1.00 24.67  ? 336  LEU E CG    1 
ATOM   15750 C CD1   . LEU E 1 336 ? -67.425  -7.350   -65.280 1.00 21.27  ? 336  LEU E CD1   1 
ATOM   15751 C CD2   . LEU E 1 336 ? -68.224  -5.089   -64.532 1.00 24.34  ? 336  LEU E CD2   1 
ATOM   15752 N N     . CYS E 1 337 ? -66.627  -5.425   -59.678 1.00 25.71  ? 337  CYS E N     1 
ATOM   15753 C CA    . CYS E 1 337 ? -66.390  -5.870   -58.313 1.00 28.47  ? 337  CYS E CA    1 
ATOM   15754 C C     . CYS E 1 337 ? -67.483  -6.873   -57.965 1.00 27.31  ? 337  CYS E C     1 
ATOM   15755 O O     . CYS E 1 337 ? -68.652  -6.511   -57.887 1.00 24.04  ? 337  CYS E O     1 
ATOM   15756 C CB    . CYS E 1 337 ? -66.367  -4.678   -57.353 1.00 30.93  ? 337  CYS E CB    1 
ATOM   15757 S SG    . CYS E 1 337 ? -65.061  -3.488   -57.789 1.00 32.62  ? 337  CYS E SG    1 
ATOM   15758 N N     . ILE E 1 338 ? -67.082  -8.137   -57.804 1.00 22.08  ? 338  ILE E N     1 
ATOM   15759 C CA    . ILE E 1 338 ? -68.056  -9.208   -57.789 1.00 21.84  ? 338  ILE E CA    1 
ATOM   15760 C C     . ILE E 1 338 ? -68.027  -9.916   -56.435 1.00 20.08  ? 338  ILE E C     1 
ATOM   15761 O O     . ILE E 1 338 ? -66.959  -10.298  -55.968 1.00 18.22  ? 338  ILE E O     1 
ATOM   15762 C CB    . ILE E 1 338 ? -67.813  -10.122  -59.006 1.00 22.60  ? 338  ILE E CB    1 
ATOM   15763 C CG1   . ILE E 1 338 ? -68.192  -9.324   -60.268 1.00 24.07  ? 338  ILE E CG1   1 
ATOM   15764 C CG2   . ILE E 1 338 ? -68.657  -11.387  -58.880 1.00 19.53  ? 338  ILE E CG2   1 
ATOM   15765 C CD1   . ILE E 1 338 ? -67.923  -10.053  -61.563 1.00 32.68  ? 338  ILE E CD1   1 
ATOM   15766 N N     . LEU E 1 339 ? -69.203  -10.008  -55.796 1.00 20.42  ? 339  LEU E N     1 
ATOM   15767 C CA    . LEU E 1 339 ? -69.376  -10.541  -54.448 1.00 21.18  ? 339  LEU E CA    1 
ATOM   15768 C C     . LEU E 1 339 ? -70.055  -11.921  -54.487 1.00 24.35  ? 339  LEU E C     1 
ATOM   15769 O O     . LEU E 1 339 ? -70.617  -12.323  -55.517 1.00 21.15  ? 339  LEU E O     1 
ATOM   15770 C CB    . LEU E 1 339 ? -70.154  -9.548   -53.589 1.00 19.38  ? 339  LEU E CB    1 
ATOM   15771 C CG    . LEU E 1 339 ? -69.355  -8.315   -53.118 1.00 23.00  ? 339  LEU E CG    1 
ATOM   15772 C CD1   . LEU E 1 339 ? -69.065  -7.287   -54.219 1.00 19.24  ? 339  LEU E CD1   1 
ATOM   15773 C CD2   . LEU E 1 339 ? -69.929  -7.608   -51.884 1.00 19.80  ? 339  LEU E CD2   1 
ATOM   15774 N N     . ASP E 1 340 ? -69.966  -12.649  -53.355 1.00 24.92  ? 340  ASP E N     1 
ATOM   15775 C CA    . ASP E 1 340 ? -70.705  -13.892  -53.165 1.00 23.83  ? 340  ASP E CA    1 
ATOM   15776 C C     . ASP E 1 340 ? -70.236  -14.967  -54.144 1.00 24.72  ? 340  ASP E C     1 
ATOM   15777 O O     . ASP E 1 340 ? -71.052  -15.703  -54.687 1.00 25.69  ? 340  ASP E O     1 
ATOM   15778 C CB    . ASP E 1 340 ? -72.209  -13.658  -53.256 1.00 22.57  ? 340  ASP E CB    1 
ATOM   15779 C CG    . ASP E 1 340 ? -72.685  -12.554  -52.316 1.00 30.40  ? 340  ASP E CG    1 
ATOM   15780 O OD1   . ASP E 1 340 ? -72.406  -12.660  -51.096 1.00 29.70  ? 340  ASP E OD1   1 
ATOM   15781 O OD2   . ASP E 1 340 ? -73.251  -11.544  -52.799 1.00 30.39  ? 340  ASP E OD2   1 
ATOM   15782 N N     . LEU E 1 341 ? -68.927  -15.049  -54.391 1.00 21.64  ? 341  LEU E N     1 
ATOM   15783 C CA    . LEU E 1 341 ? -68.385  -16.137  -55.194 1.00 21.89  ? 341  LEU E CA    1 
ATOM   15784 C C     . LEU E 1 341 ? -67.987  -17.282  -54.281 1.00 24.17  ? 341  LEU E C     1 
ATOM   15785 O O     . LEU E 1 341 ? -67.651  -17.080  -53.108 1.00 23.90  ? 341  LEU E O     1 
ATOM   15786 C CB    . LEU E 1 341 ? -67.175  -15.647  -55.981 1.00 20.62  ? 341  LEU E CB    1 
ATOM   15787 C CG    . LEU E 1 341 ? -67.489  -14.639  -57.101 1.00 24.10  ? 341  LEU E CG    1 
ATOM   15788 C CD1   . LEU E 1 341 ? -66.187  -14.245  -57.759 1.00 20.76  ? 341  LEU E CD1   1 
ATOM   15789 C CD2   . LEU E 1 341 ? -68.467  -15.246  -58.146 1.00 19.51  ? 341  LEU E CD2   1 
ATOM   15790 N N     . GLN E 1 342 ? -67.931  -18.485  -54.854 1.00 28.04  ? 342  GLN E N     1 
ATOM   15791 C CA    . GLN E 1 342 ? -67.490  -19.642  -54.077 1.00 27.93  ? 342  GLN E CA    1 
ATOM   15792 C C     . GLN E 1 342 ? -66.221  -20.245  -54.657 1.00 26.13  ? 342  GLN E C     1 
ATOM   15793 O O     . GLN E 1 342 ? -65.786  -19.851  -55.741 1.00 27.24  ? 342  GLN E O     1 
ATOM   15794 C CB    . GLN E 1 342 ? -68.694  -20.576  -54.027 1.00 32.13  ? 342  GLN E CB    1 
ATOM   15795 C CG    . GLN E 1 342 ? -69.762  -20.024  -53.091 1.00 36.74  ? 342  GLN E CG    1 
ATOM   15796 C CD    . GLN E 1 342 ? -70.880  -21.028  -52.970 1.00 49.25  ? 342  GLN E CD    1 
ATOM   15797 O OE1   . GLN E 1 342 ? -71.705  -21.169  -53.875 1.00 53.17  ? 342  GLN E OE1   1 
ATOM   15798 N NE2   . GLN E 1 342 ? -70.870  -21.790  -51.888 1.00 56.34  ? 342  GLN E NE2   1 
ATOM   15799 N N     . VAL E 1 343 ? -65.636  -21.202  -53.919 1.00 26.99  ? 343  VAL E N     1 
ATOM   15800 C CA    . VAL E 1 343 ? -64.404  -21.859  -54.337 1.00 27.10  ? 343  VAL E CA    1 
ATOM   15801 C C     . VAL E 1 343 ? -64.730  -22.992  -55.315 1.00 31.92  ? 343  VAL E C     1 
ATOM   15802 O O     . VAL E 1 343 ? -65.787  -23.625  -55.225 1.00 34.86  ? 343  VAL E O     1 
ATOM   15803 C CB    . VAL E 1 343 ? -63.651  -22.348  -53.090 1.00 27.13  ? 343  VAL E CB    1 
ATOM   15804 C CG1   . VAL E 1 343 ? -62.344  -23.040  -53.463 1.00 27.11  ? 343  VAL E CG1   1 
ATOM   15805 C CG2   . VAL E 1 343 ? -63.368  -21.196  -52.126 1.00 24.23  ? 343  VAL E CG2   1 
ATOM   15806 N N     . VAL E 1 344 ? -63.840  -23.211  -56.288 1.00 30.96  ? 344  VAL E N     1 
ATOM   15807 C CA    . VAL E 1 344 ? -63.992  -24.275  -57.281 1.00 35.16  ? 344  VAL E CA    1 
ATOM   15808 C C     . VAL E 1 344 ? -63.227  -25.526  -56.823 1.00 37.19  ? 344  VAL E C     1 
ATOM   15809 O O     . VAL E 1 344 ? -62.008  -25.460  -56.661 1.00 37.17  ? 344  VAL E O     1 
ATOM   15810 C CB    . VAL E 1 344 ? -63.445  -23.775  -58.637 1.00 31.35  ? 344  VAL E CB    1 
ATOM   15811 C CG1   . VAL E 1 344 ? -63.343  -24.903  -59.672 1.00 29.18  ? 344  VAL E CG1   1 
ATOM   15812 C CG2   . VAL E 1 344 ? -64.273  -22.613  -59.177 1.00 31.88  ? 344  VAL E CG2   1 
ATOM   15813 N N     . GLY E 1 345 ? -63.937  -26.664  -56.685 1.00 42.17  ? 345  GLY E N     1 
ATOM   15814 C CA    . GLY E 1 345 ? -63.356  -27.995  -56.515 1.00 44.48  ? 345  GLY E CA    1 
ATOM   15815 C C     . GLY E 1 345 ? -62.942  -28.669  -57.827 1.00 49.26  ? 345  GLY E C     1 
ATOM   15816 O O     . GLY E 1 345 ? -62.383  -28.035  -58.727 1.00 48.54  ? 345  GLY E O     1 
ATOM   15817 N N     . LYS E 1 346 ? -63.158  -29.987  -57.922 1.00 60.72  ? 346  LYS E N     1 
ATOM   15818 C CA    . LYS E 1 346 ? -62.791  -30.734  -59.122 1.00 63.79  ? 346  LYS E CA    1 
ATOM   15819 C C     . LYS E 1 346 ? -63.515  -32.076  -59.097 1.00 60.87  ? 346  LYS E C     1 
ATOM   15820 O O     . LYS E 1 346 ? -63.490  -32.749  -58.063 1.00 49.66  ? 346  LYS E O     1 
ATOM   15821 C CB    . LYS E 1 346 ? -61.283  -31.023  -59.226 1.00 58.15  ? 346  LYS E CB    1 
ATOM   15822 C CG    . LYS E 1 346 ? -60.835  -31.551  -60.568 1.00 63.94  ? 346  LYS E CG    1 
ATOM   15823 C CD    . LYS E 1 346 ? -59.374  -31.998  -60.640 1.00 67.23  ? 346  LYS E CD    1 
ATOM   15824 C CE    . LYS E 1 346 ? -58.846  -32.110  -62.047 1.00 70.30  ? 346  LYS E CE    1 
ATOM   15825 N NZ    . LYS E 1 346 ? -57.539  -31.452  -62.181 1.00 64.23  ? 346  LYS E NZ    1 
ATOM   15826 N N     . ASP E 1 347 ? -64.154  -32.421  -60.227 1.00 71.17  ? 347  ASP E N     1 
ATOM   15827 C CA    . ASP E 1 347 ? -64.833  -33.699  -60.448 1.00 78.53  ? 347  ASP E CA    1 
ATOM   15828 C C     . ASP E 1 347 ? -65.881  -33.955  -59.369 1.00 72.76  ? 347  ASP E C     1 
ATOM   15829 O O     . ASP E 1 347 ? -66.864  -33.235  -59.311 1.00 66.04  ? 347  ASP E O     1 
ATOM   15830 C CB    . ASP E 1 347 ? -63.853  -34.848  -60.682 1.00 84.63  ? 347  ASP E CB    1 
ATOM   15831 C CG    . ASP E 1 347 ? -62.868  -34.655  -61.836 1.00 102.08 ? 347  ASP E CG    1 
ATOM   15832 O OD1   . ASP E 1 347 ? -63.312  -34.227  -62.936 1.00 100.90 ? 347  ASP E OD1   1 
ATOM   15833 O OD2   . ASP E 1 347 ? -61.670  -34.979  -61.652 1.00 91.46  ? 347  ASP E OD2   1 
ATOM   15834 N N     . ASN E 1 348 ? -65.638  -34.965  -58.521 1.00 83.93  ? 348  ASN E N     1 
ATOM   15835 C CA    . ASN E 1 348 ? -66.556  -35.410  -57.479 1.00 83.81  ? 348  ASN E CA    1 
ATOM   15836 C C     . ASN E 1 348 ? -66.613  -34.408  -56.316 1.00 76.57  ? 348  ASN E C     1 
ATOM   15837 O O     . ASN E 1 348 ? -67.585  -34.396  -55.553 1.00 78.70  ? 348  ASN E O     1 
ATOM   15838 C CB    . ASN E 1 348 ? -66.114  -36.732  -56.843 1.00 82.48  ? 348  ASN E CB    1 
ATOM   15839 C CG    . ASN E 1 348 ? -65.972  -37.894  -57.794 1.00 103.39 ? 348  ASN E CG    1 
ATOM   15840 O OD1   . ASN E 1 348 ? -65.140  -37.853  -58.701 1.00 116.78 ? 348  ASN E OD1   1 
ATOM   15841 N ND2   . ASN E 1 348 ? -66.715  -38.969  -57.570 1.00 103.66 ? 348  ASN E ND2   1 
ATOM   15842 N N     . VAL E 1 349 ? -65.549  -33.596  -56.170 1.00 82.30  ? 349  VAL E N     1 
ATOM   15843 C CA    . VAL E 1 349 ? -65.401  -32.662  -55.057 1.00 76.72  ? 349  VAL E CA    1 
ATOM   15844 C C     . VAL E 1 349 ? -65.998  -31.305  -55.446 1.00 65.08  ? 349  VAL E C     1 
ATOM   15845 O O     . VAL E 1 349 ? -65.396  -30.534  -56.194 1.00 58.52  ? 349  VAL E O     1 
ATOM   15846 C CB    . VAL E 1 349 ? -63.945  -32.534  -54.555 1.00 64.87  ? 349  VAL E CB    1 
ATOM   15847 C CG1   . VAL E 1 349 ? -63.861  -31.800  -53.214 1.00 64.19  ? 349  VAL E CG1   1 
ATOM   15848 C CG2   . VAL E 1 349 ? -63.271  -33.899  -54.480 1.00 62.21  ? 349  VAL E CG2   1 
ATOM   15849 N N     . VAL E 1 350 ? -67.194  -31.033  -54.910 1.00 59.29  ? 350  VAL E N     1 
ATOM   15850 C CA    . VAL E 1 350 ? -68.011  -29.882  -55.263 1.00 60.03  ? 350  VAL E CA    1 
ATOM   15851 C C     . VAL E 1 350 ? -67.946  -28.889  -54.097 1.00 61.80  ? 350  VAL E C     1 
ATOM   15852 O O     . VAL E 1 350 ? -68.384  -29.220  -52.983 1.00 53.51  ? 350  VAL E O     1 
ATOM   15853 C CB    . VAL E 1 350 ? -69.462  -30.334  -55.566 1.00 52.67  ? 350  VAL E CB    1 
ATOM   15854 C CG1   . VAL E 1 350 ? -70.445  -29.166  -55.740 1.00 47.26  ? 350  VAL E CG1   1 
ATOM   15855 C CG2   . VAL E 1 350 ? -69.526  -31.247  -56.794 1.00 50.93  ? 350  VAL E CG2   1 
ATOM   15856 N N     . LEU E 1 351 ? -67.392  -27.686  -54.364 1.00 51.48  ? 351  LEU E N     1 
ATOM   15857 C CA    . LEU E 1 351 ? -67.258  -26.660  -53.335 1.00 47.08  ? 351  LEU E CA    1 
ATOM   15858 C C     . LEU E 1 351 ? -68.257  -25.503  -53.518 1.00 43.71  ? 351  LEU E C     1 
ATOM   15859 O O     . LEU E 1 351 ? -68.410  -24.680  -52.611 1.00 50.79  ? 351  LEU E O     1 
ATOM   15860 C CB    . LEU E 1 351 ? -65.805  -26.202  -53.185 1.00 43.38  ? 351  LEU E CB    1 
ATOM   15861 C CG    . LEU E 1 351 ? -64.779  -27.304  -52.893 1.00 42.58  ? 351  LEU E CG    1 
ATOM   15862 C CD1   . LEU E 1 351 ? -63.379  -26.762  -53.022 1.00 36.95  ? 351  LEU E CD1   1 
ATOM   15863 C CD2   . LEU E 1 351 ? -64.984  -27.966  -51.527 1.00 38.65  ? 351  LEU E CD2   1 
ATOM   15864 N N     . GLY E 1 352 ? -68.935  -25.432  -54.681 1.00 40.25  ? 352  GLY E N     1 
ATOM   15865 C CA    . GLY E 1 352 ? -69.985  -24.443  -54.907 1.00 38.79  ? 352  GLY E CA    1 
ATOM   15866 C C     . GLY E 1 352 ? -69.748  -23.543  -56.128 1.00 42.59  ? 352  GLY E C     1 
ATOM   15867 O O     . GLY E 1 352 ? -70.704  -23.032  -56.711 1.00 40.21  ? 352  GLY E O     1 
ATOM   15868 N N     . GLY E 1 353 ? -68.481  -23.364  -56.538 1.00 46.52  ? 353  GLY E N     1 
ATOM   15869 C CA    . GLY E 1 353 ? -68.146  -22.343  -57.529 1.00 42.93  ? 353  GLY E CA    1 
ATOM   15870 C C     . GLY E 1 353 ? -68.078  -22.862  -58.971 1.00 46.01  ? 353  GLY E C     1 
ATOM   15871 O O     . GLY E 1 353 ? -67.797  -22.074  -59.874 1.00 44.25  ? 353  GLY E O     1 
ATOM   15872 N N     . GLU E 1 354 ? -68.371  -24.160  -59.206 1.00 46.22  ? 354  GLU E N     1 
ATOM   15873 C CA    . GLU E 1 354 ? -67.986  -24.789  -60.470 1.00 54.81  ? 354  GLU E CA    1 
ATOM   15874 C C     . GLU E 1 354 ? -68.938  -24.519  -61.652 1.00 48.28  ? 354  GLU E C     1 
ATOM   15875 O O     . GLU E 1 354 ? -68.470  -24.515  -62.791 1.00 51.01  ? 354  GLU E O     1 
ATOM   15876 C CB    . GLU E 1 354 ? -67.308  -26.163  -60.407 1.00 59.28  ? 354  GLU E CB    1 
ATOM   15877 C CG    . GLU E 1 354 ? -67.906  -27.130  -59.396 1.00 54.32  ? 354  GLU E CG    1 
ATOM   15878 C CD    . GLU E 1 354 ? -67.742  -26.822  -57.906 1.00 56.87  ? 354  GLU E CD    1 
ATOM   15879 O OE1   . GLU E 1 354 ? -68.770  -26.383  -57.316 1.00 50.59  ? 354  GLU E OE1   1 
ATOM   15880 O OE2   . GLU E 1 354 ? -66.655  -27.057  -57.315 1.00 44.00  ? 354  GLU E OE2   1 
ATOM   15881 N N     . GLY E 1 355 ? -70.245  -24.289  -61.424 1.00 36.29  ? 355  GLY E N     1 
ATOM   15882 C CA    . GLY E 1 355 ? -71.143  -24.069  -62.552 1.00 32.46  ? 355  GLY E CA    1 
ATOM   15883 C C     . GLY E 1 355 ? -70.889  -22.713  -63.233 1.00 31.90  ? 355  GLY E C     1 
ATOM   15884 O O     . GLY E 1 355 ? -70.330  -21.807  -62.618 1.00 38.46  ? 355  GLY E O     1 
ATOM   15885 N N     . VAL E 1 356 ? -71.304  -22.559  -64.494 1.00 25.61  ? 356  VAL E N     1 
ATOM   15886 C CA    . VAL E 1 356 ? -71.344  -21.242  -65.100 1.00 23.41  ? 356  VAL E CA    1 
ATOM   15887 C C     . VAL E 1 356 ? -72.177  -20.288  -64.242 1.00 23.23  ? 356  VAL E C     1 
ATOM   15888 O O     . VAL E 1 356 ? -73.251  -20.643  -63.778 1.00 21.78  ? 356  VAL E O     1 
ATOM   15889 C CB    . VAL E 1 356 ? -71.893  -21.398  -66.522 1.00 23.33  ? 356  VAL E CB    1 
ATOM   15890 C CG1   . VAL E 1 356 ? -72.069  -20.057  -67.218 1.00 19.10  ? 356  VAL E CG1   1 
ATOM   15891 C CG2   . VAL E 1 356 ? -71.021  -22.367  -67.347 1.00 21.45  ? 356  VAL E CG2   1 
ATOM   15892 N N     . ASN E 1 357 ? -71.681  -19.055  -64.057 1.00 21.75  ? 357  ASN E N     1 
ATOM   15893 C CA    . ASN E 1 357 ? -72.222  -18.127  -63.069 1.00 23.23  ? 357  ASN E CA    1 
ATOM   15894 C C     . ASN E 1 357 ? -72.422  -16.767  -63.748 1.00 25.73  ? 357  ASN E C     1 
ATOM   15895 O O     . ASN E 1 357 ? -71.598  -15.860  -63.626 1.00 22.51  ? 357  ASN E O     1 
ATOM   15896 C CB    . ASN E 1 357 ? -71.295  -18.058  -61.862 1.00 21.54  ? 357  ASN E CB    1 
ATOM   15897 C CG    . ASN E 1 357 ? -71.684  -17.045  -60.812 1.00 26.29  ? 357  ASN E CG    1 
ATOM   15898 O OD1   . ASN E 1 357 ? -72.845  -16.627  -60.697 1.00 24.66  ? 357  ASN E OD1   1 
ATOM   15899 N ND2   . ASN E 1 357 ? -70.698  -16.608  -60.040 1.00 33.00  ? 357  ASN E ND2   1 
ATOM   15900 N N     . PRO E 1 358 ? -73.506  -16.585  -64.532 1.00 25.17  ? 358  PRO E N     1 
ATOM   15901 C CA    . PRO E 1 358 ? -73.694  -15.337  -65.269 1.00 23.40  ? 358  PRO E CA    1 
ATOM   15902 C C     . PRO E 1 358 ? -74.026  -14.150  -64.361 1.00 24.86  ? 358  PRO E C     1 
ATOM   15903 O O     . PRO E 1 358 ? -75.024  -14.179  -63.657 1.00 23.55  ? 358  PRO E O     1 
ATOM   15904 C CB    . PRO E 1 358 ? -74.797  -15.641  -66.273 1.00 20.88  ? 358  PRO E CB    1 
ATOM   15905 C CG    . PRO E 1 358 ? -75.465  -16.859  -65.693 1.00 25.77  ? 358  PRO E CG    1 
ATOM   15906 C CD    . PRO E 1 358 ? -74.560  -17.577  -64.748 1.00 22.28  ? 358  PRO E CD    1 
ATOM   15907 N N     . ARG E 1 359 ? -73.168  -13.117  -64.369 1.00 23.59  ? 359  ARG E N     1 
ATOM   15908 C CA    . ARG E 1 359 ? -73.405  -11.890  -63.628 1.00 19.69  ? 359  ARG E CA    1 
ATOM   15909 C C     . ARG E 1 359 ? -73.546  -10.767  -64.650 1.00 20.65  ? 359  ARG E C     1 
ATOM   15910 O O     . ARG E 1 359 ? -72.672  -10.581  -65.510 1.00 21.91  ? 359  ARG E O     1 
ATOM   15911 C CB    . ARG E 1 359 ? -72.235  -11.635  -62.664 1.00 19.33  ? 359  ARG E CB    1 
ATOM   15912 C CG    . ARG E 1 359 ? -72.010  -12.723  -61.613 1.00 21.06  ? 359  ARG E CG    1 
ATOM   15913 C CD    . ARG E 1 359 ? -73.225  -12.870  -60.668 1.00 19.31  ? 359  ARG E CD    1 
ATOM   15914 N NE    . ARG E 1 359 ? -73.012  -13.821  -59.577 1.00 21.09  ? 359  ARG E NE    1 
ATOM   15915 C CZ    . ARG E 1 359 ? -72.383  -13.542  -58.431 1.00 21.46  ? 359  ARG E CZ    1 
ATOM   15916 N NH1   . ARG E 1 359 ? -72.101  -12.275  -58.133 1.00 19.37  ? 359  ARG E NH1   1 
ATOM   15917 N NH2   . ARG E 1 359 ? -72.051  -14.534  -57.587 1.00 18.29  ? 359  ARG E NH2   1 
ATOM   15918 N N     . SER E 1 360 ? -74.632  -10.006  -64.534 1.00 20.51  ? 360  SER E N     1 
ATOM   15919 C CA    . SER E 1 360 ? -74.984  -8.988   -65.510 1.00 22.79  ? 360  SER E CA    1 
ATOM   15920 C C     . SER E 1 360 ? -74.906  -7.579   -64.936 1.00 25.78  ? 360  SER E C     1 
ATOM   15921 O O     . SER E 1 360 ? -75.050  -7.380   -63.722 1.00 22.89  ? 360  SER E O     1 
ATOM   15922 C CB    . SER E 1 360 ? -76.331  -9.244   -66.144 1.00 22.62  ? 360  SER E CB    1 
ATOM   15923 O OG    . SER E 1 360 ? -76.285  -10.477  -66.870 1.00 25.28  ? 360  SER E OG    1 
ATOM   15924 N N     . PHE E 1 361 ? -74.692  -6.623   -65.861 1.00 24.56  ? 361  PHE E N     1 
ATOM   15925 C CA    . PHE E 1 361 ? -74.541  -5.208   -65.582 1.00 22.41  ? 361  PHE E CA    1 
ATOM   15926 C C     . PHE E 1 361 ? -75.257  -4.468   -66.701 1.00 25.07  ? 361  PHE E C     1 
ATOM   15927 O O     . PHE E 1 361 ? -75.283  -4.946   -67.835 1.00 26.53  ? 361  PHE E O     1 
ATOM   15928 C CB    . PHE E 1 361 ? -73.046  -4.884   -65.600 1.00 20.83  ? 361  PHE E CB    1 
ATOM   15929 C CG    . PHE E 1 361 ? -72.310  -5.690   -64.543 1.00 26.24  ? 361  PHE E CG    1 
ATOM   15930 C CD1   . PHE E 1 361 ? -72.196  -5.233   -63.218 1.00 24.87  ? 361  PHE E CD1   1 
ATOM   15931 C CD2   . PHE E 1 361 ? -71.786  -6.954   -64.864 1.00 26.10  ? 361  PHE E CD2   1 
ATOM   15932 C CE1   . PHE E 1 361 ? -71.537  -6.005   -62.262 1.00 24.25  ? 361  PHE E CE1   1 
ATOM   15933 C CE2   . PHE E 1 361 ? -71.128  -7.721   -63.898 1.00 24.38  ? 361  PHE E CE2   1 
ATOM   15934 C CZ    . PHE E 1 361 ? -71.028  -7.260   -62.600 1.00 22.13  ? 361  PHE E CZ    1 
ATOM   15935 N N     . VAL E 1 362 ? -75.825  -3.314   -66.365 1.00 22.98  ? 362  VAL E N     1 
ATOM   15936 C CA    . VAL E 1 362 ? -76.556  -2.474   -67.292 1.00 26.74  ? 362  VAL E CA    1 
ATOM   15937 C C     . VAL E 1 362 ? -75.902  -1.102   -67.277 1.00 28.88  ? 362  VAL E C     1 
ATOM   15938 O O     . VAL E 1 362 ? -75.757  -0.515   -66.206 1.00 30.27  ? 362  VAL E O     1 
ATOM   15939 C CB    . VAL E 1 362 ? -78.026  -2.330   -66.865 1.00 29.21  ? 362  VAL E CB    1 
ATOM   15940 C CG1   . VAL E 1 362 ? -78.770  -1.351   -67.769 1.00 24.36  ? 362  VAL E CG1   1 
ATOM   15941 C CG2   . VAL E 1 362 ? -78.708  -3.684   -66.759 1.00 27.33  ? 362  VAL E CG2   1 
ATOM   15942 N N     . GLY E 1 363 ? -75.529  -0.601   -68.457 1.00 29.28  ? 363  GLY E N     1 
ATOM   15943 C CA    . GLY E 1 363 ? -74.942  0.722    -68.552 1.00 26.29  ? 363  GLY E CA    1 
ATOM   15944 C C     . GLY E 1 363 ? -73.589  0.717    -69.265 1.00 27.57  ? 363  GLY E C     1 
ATOM   15945 O O     . GLY E 1 363 ? -72.975  1.759    -69.408 1.00 33.19  ? 363  GLY E O     1 
ATOM   15946 N N     . ILE E 1 364 ? -73.133  -0.436   -69.753 1.00 28.54  ? 364  ILE E N     1 
ATOM   15947 C CA    . ILE E 1 364 ? -71.907  -0.492   -70.520 1.00 27.88  ? 364  ILE E CA    1 
ATOM   15948 C C     . ILE E 1 364 ? -72.253  -0.529   -72.008 1.00 32.70  ? 364  ILE E C     1 
ATOM   15949 O O     . ILE E 1 364 ? -72.845  -1.495   -72.486 1.00 34.76  ? 364  ILE E O     1 
ATOM   15950 C CB    . ILE E 1 364 ? -71.067  -1.679   -70.039 1.00 30.23  ? 364  ILE E CB    1 
ATOM   15951 C CG1   . ILE E 1 364 ? -70.498  -1.327   -68.673 1.00 33.14  ? 364  ILE E CG1   1 
ATOM   15952 C CG2   . ILE E 1 364 ? -69.954  -1.996   -71.042 1.00 26.69  ? 364  ILE E CG2   1 
ATOM   15953 C CD1   . ILE E 1 364 ? -69.767  -2.455   -68.002 1.00 38.96  ? 364  ILE E CD1   1 
ATOM   15954 N N     . GLY E 1 365 ? -71.882  0.541    -72.725 1.00 36.97  ? 365  GLY E N     1 
ATOM   15955 C CA    . GLY E 1 365 ? -72.321  0.764    -74.102 1.00 38.43  ? 365  GLY E CA    1 
ATOM   15956 C C     . GLY E 1 365 ? -71.218  0.560    -75.150 1.00 34.18  ? 365  GLY E C     1 
ATOM   15957 O O     . GLY E 1 365 ? -71.505  0.570    -76.332 1.00 42.21  ? 365  GLY E O     1 
ATOM   15958 N N     . GLN E 1 366 ? -69.978  0.311    -74.732 1.00 35.03  ? 366  GLN E N     1 
ATOM   15959 C CA    . GLN E 1 366 ? -68.843  0.198    -75.641 1.00 37.27  ? 366  GLN E CA    1 
ATOM   15960 C C     . GLN E 1 366 ? -68.457  -1.262   -75.822 1.00 34.80  ? 366  GLN E C     1 
ATOM   15961 O O     . GLN E 1 366 ? -68.489  -2.034   -74.870 1.00 34.86  ? 366  GLN E O     1 
ATOM   15962 C CB    . GLN E 1 366 ? -67.635  1.001    -75.126 1.00 41.70  ? 366  GLN E CB    1 
ATOM   15963 C CG    . GLN E 1 366 ? -67.851  2.516    -75.107 1.00 51.27  ? 366  GLN E CG    1 
ATOM   15964 C CD    . GLN E 1 366 ? -68.401  3.036    -76.435 1.00 76.12  ? 366  GLN E CD    1 
ATOM   15965 O OE1   . GLN E 1 366 ? -67.835  2.813    -77.523 1.00 63.98  ? 366  GLN E OE1   1 
ATOM   15966 N NE2   . GLN E 1 366 ? -69.537  3.726    -76.374 1.00 76.10  ? 366  GLN E NE2   1 
ATOM   15967 N N     . PRO E 1 367 ? -68.059  -1.699   -77.039 1.00 39.80  ? 367  PRO E N     1 
ATOM   15968 C CA    . PRO E 1 367 ? -67.609  -3.081   -77.227 1.00 33.18  ? 367  PRO E CA    1 
ATOM   15969 C C     . PRO E 1 367 ? -66.350  -3.393   -76.430 1.00 33.70  ? 367  PRO E C     1 
ATOM   15970 O O     . PRO E 1 367 ? -65.448  -2.549   -76.331 1.00 33.68  ? 367  PRO E O     1 
ATOM   15971 C CB    . PRO E 1 367 ? -67.334  -3.212   -78.736 1.00 36.45  ? 367  PRO E CB    1 
ATOM   15972 C CG    . PRO E 1 367 ? -67.450  -1.799   -79.297 1.00 38.17  ? 367  PRO E CG    1 
ATOM   15973 C CD    . PRO E 1 367 ? -68.093  -0.905   -78.281 1.00 37.93  ? 367  PRO E CD    1 
ATOM   15974 N N     . ILE E 1 368 ? -66.276  -4.591   -75.886 1.00 29.92  ? 368  ILE E N     1 
ATOM   15975 C CA    . ILE E 1 368 ? -65.191  -5.003   -75.033 1.00 29.75  ? 368  ILE E CA    1 
ATOM   15976 C C     . ILE E 1 368 ? -64.238  -5.982   -75.664 1.00 31.28  ? 368  ILE E C     1 
ATOM   15977 O O     . ILE E 1 368 ? -64.631  -6.898   -76.303 1.00 33.38  ? 368  ILE E O     1 
ATOM   15978 C CB    . ILE E 1 368 ? -65.754  -5.591   -73.713 1.00 25.22  ? 368  ILE E CB    1 
ATOM   15979 C CG1   . ILE E 1 368 ? -66.417  -4.504   -72.894 1.00 27.74  ? 368  ILE E CG1   1 
ATOM   15980 C CG2   . ILE E 1 368 ? -64.690  -6.279   -72.906 1.00 20.08  ? 368  ILE E CG2   1 
ATOM   15981 C CD1   . ILE E 1 368 ? -67.292  -4.970   -71.775 1.00 23.52  ? 368  ILE E CD1   1 
ATOM   15982 N N     . GLN E 1 369 ? -62.970  -5.665   -75.627 1.00 30.53  ? 369  GLN E N     1 
ATOM   15983 C CA    . GLN E 1 369 ? -61.986  -6.600   -76.072 1.00 38.53  ? 369  GLN E CA    1 
ATOM   15984 C C     . GLN E 1 369 ? -61.684  -7.784   -75.137 1.00 36.57  ? 369  GLN E C     1 
ATOM   15985 O O     . GLN E 1 369 ? -61.671  -8.889   -75.546 1.00 34.84  ? 369  GLN E O     1 
ATOM   15986 C CB    . GLN E 1 369 ? -60.711  -5.866   -76.455 1.00 44.80  ? 369  GLN E CB    1 
ATOM   15987 C CG    . GLN E 1 369 ? -59.561  -6.742   -76.857 1.00 53.78  ? 369  GLN E CG    1 
ATOM   15988 C CD    . GLN E 1 369 ? -58.250  -6.190   -76.369 1.00 74.55  ? 369  GLN E CD    1 
ATOM   15989 O OE1   . GLN E 1 369 ? -57.840  -5.103   -76.748 1.00 70.03  ? 369  GLN E OE1   1 
ATOM   15990 N NE2   . GLN E 1 369 ? -57.582  -6.939   -75.504 1.00 85.44  ? 369  GLN E NE2   1 
ATOM   15991 N N     . ARG E 1 370 ? -61.484  -7.531   -73.863 1.00 37.23  ? 370  ARG E N     1 
ATOM   15992 C CA    . ARG E 1 370 ? -61.122  -8.573   -72.929 1.00 39.15  ? 370  ARG E CA    1 
ATOM   15993 C C     . ARG E 1 370 ? -61.497  -8.257   -71.499 1.00 37.17  ? 370  ARG E C     1 
ATOM   15994 O O     . ARG E 1 370 ? -61.494  -7.132   -71.115 1.00 32.95  ? 370  ARG E O     1 
ATOM   15995 C CB    . ARG E 1 370 ? -59.609  -8.682   -72.972 1.00 41.20  ? 370  ARG E CB    1 
ATOM   15996 C CG    . ARG E 1 370 ? -59.011  -10.041  -72.802 1.00 52.16  ? 370  ARG E CG    1 
ATOM   15997 C CD    . ARG E 1 370 ? -57.503  -9.959   -72.964 1.00 70.76  ? 370  ARG E CD    1 
ATOM   15998 N NE    . ARG E 1 370 ? -56.824  -9.928   -71.678 1.00 93.39  ? 370  ARG E NE    1 
ATOM   15999 C CZ    . ARG E 1 370 ? -55.942  -10.824  -71.257 1.00 91.58  ? 370  ARG E CZ    1 
ATOM   16000 N NH1   . ARG E 1 370 ? -55.575  -11.818  -72.044 1.00 76.51  ? 370  ARG E NH1   1 
ATOM   16001 N NH2   . ARG E 1 370 ? -55.415  -10.712  -70.049 1.00 80.67  ? 370  ARG E NH2   1 
ATOM   16002 N N     . ILE E 1 371 ? -61.821  -9.274   -70.721 1.00 31.25  ? 371  ILE E N     1 
ATOM   16003 C CA    . ILE E 1 371 ? -62.122  -9.147   -69.309 1.00 28.29  ? 371  ILE E CA    1 
ATOM   16004 C C     . ILE E 1 371 ? -61.312  -10.183  -68.538 1.00 30.16  ? 371  ILE E C     1 
ATOM   16005 O O     . ILE E 1 371 ? -61.305  -11.311  -68.911 1.00 30.44  ? 371  ILE E O     1 
ATOM   16006 C CB    . ILE E 1 371 ? -63.603  -9.362   -69.002 1.00 28.69  ? 371  ILE E CB    1 
ATOM   16007 C CG1   . ILE E 1 371 ? -64.467  -8.495   -69.886 1.00 24.38  ? 371  ILE E CG1   1 
ATOM   16008 C CG2   . ILE E 1 371 ? -63.865  -9.070   -67.551 1.00 28.66  ? 371  ILE E CG2   1 
ATOM   16009 C CD1   . ILE E 1 371 ? -65.930  -8.553   -69.619 1.00 25.51  ? 371  ILE E CD1   1 
ATOM   16010 N N     . HIS E 1 372 ? -60.630  -9.805   -67.469 1.00 24.35  ? 372  HIS E N     1 
ATOM   16011 C CA    . HIS E 1 372 ? -59.853  -10.747  -66.696 1.00 25.67  ? 372  HIS E CA    1 
ATOM   16012 C C     . HIS E 1 372 ? -59.795  -10.467  -65.187 1.00 26.06  ? 372  HIS E C     1 
ATOM   16013 O O     . HIS E 1 372 ? -59.809  -9.354   -64.790 1.00 25.26  ? 372  HIS E O     1 
ATOM   16014 C CB    . HIS E 1 372 ? -58.455  -10.860  -67.288 1.00 29.54  ? 372  HIS E CB    1 
ATOM   16015 C CG    . HIS E 1 372 ? -57.613  -9.649   -67.085 1.00 34.97  ? 372  HIS E CG    1 
ATOM   16016 N ND1   . HIS E 1 372 ? -57.603  -8.594   -67.956 1.00 38.26  ? 372  HIS E ND1   1 
ATOM   16017 C CD2   . HIS E 1 372 ? -56.761  -9.326   -66.095 1.00 35.79  ? 372  HIS E CD2   1 
ATOM   16018 C CE1   . HIS E 1 372 ? -56.792  -7.667   -67.504 1.00 39.96  ? 372  HIS E CE1   1 
ATOM   16019 N NE2   . HIS E 1 372 ? -56.280  -8.083   -66.371 1.00 39.07  ? 372  HIS E NE2   1 
ATOM   16020 N N     . TRP E 1 373 ? -59.707  -11.511  -64.374 1.00 23.96  ? 373  TRP E N     1 
ATOM   16021 C CA    . TRP E 1 373 ? -59.600  -11.368  -62.932 1.00 24.83  ? 373  TRP E CA    1 
ATOM   16022 C C     . TRP E 1 373 ? -58.239  -10.775  -62.574 1.00 26.81  ? 373  TRP E C     1 
ATOM   16023 O O     . TRP E 1 373 ? -57.214  -11.257  -63.061 1.00 26.57  ? 373  TRP E O     1 
ATOM   16024 C CB    . TRP E 1 373 ? -59.733  -12.750  -62.285 1.00 24.51  ? 373  TRP E CB    1 
ATOM   16025 C CG    . TRP E 1 373 ? -61.109  -13.373  -62.292 1.00 25.20  ? 373  TRP E CG    1 
ATOM   16026 C CD1   . TRP E 1 373 ? -61.391  -14.656  -62.669 1.00 21.18  ? 373  TRP E CD1   1 
ATOM   16027 C CD2   . TRP E 1 373 ? -62.359  -12.812  -61.812 1.00 23.01  ? 373  TRP E CD2   1 
ATOM   16028 N NE1   . TRP E 1 373 ? -62.724  -14.920  -62.499 1.00 20.51  ? 373  TRP E NE1   1 
ATOM   16029 C CE2   . TRP E 1 373 ? -63.342  -13.821  -61.962 1.00 21.80  ? 373  TRP E CE2   1 
ATOM   16030 C CE3   . TRP E 1 373 ? -62.741  -11.573  -61.278 1.00 24.13  ? 373  TRP E CE3   1 
ATOM   16031 C CZ2   . TRP E 1 373 ? -64.675  -13.632  -61.592 1.00 24.54  ? 373  TRP E CZ2   1 
ATOM   16032 C CZ3   . TRP E 1 373 ? -64.058  -11.386  -60.908 1.00 28.19  ? 373  TRP E CZ3   1 
ATOM   16033 C CH2   . TRP E 1 373 ? -65.020  -12.404  -61.056 1.00 28.28  ? 373  TRP E CH2   1 
ATOM   16034 N N     . LEU E 1 374 ? -58.217  -9.782   -61.669 1.00 26.10  ? 374  LEU E N     1 
ATOM   16035 C CA    . LEU E 1 374 ? -56.960  -9.197   -61.202 1.00 25.39  ? 374  LEU E CA    1 
ATOM   16036 C C     . LEU E 1 374 ? -56.134  -10.208  -60.418 1.00 27.88  ? 374  LEU E C     1 
ATOM   16037 O O     . LEU E 1 374 ? -54.923  -10.115  -60.441 1.00 31.87  ? 374  LEU E O     1 
ATOM   16038 C CB    . LEU E 1 374 ? -57.156  -7.950   -60.347 1.00 23.82  ? 374  LEU E CB    1 
ATOM   16039 C CG    . LEU E 1 374 ? -57.697  -6.735   -61.097 1.00 25.43  ? 374  LEU E CG    1 
ATOM   16040 C CD1   . LEU E 1 374 ? -57.766  -5.556   -60.122 1.00 23.16  ? 374  LEU E CD1   1 
ATOM   16041 C CD2   . LEU E 1 374 ? -56.836  -6.451   -62.339 1.00 22.45  ? 374  LEU E CD2   1 
ATOM   16042 N N     . ASP E 1 375 ? -56.761  -11.140  -59.684 1.00 25.61  ? 375  ASP E N     1 
ATOM   16043 C CA    . ASP E 1 375 ? -55.971  -11.986  -58.807 1.00 26.49  ? 375  ASP E CA    1 
ATOM   16044 C C     . ASP E 1 375 ? -55.124  -13.018  -59.576 1.00 32.33  ? 375  ASP E C     1 
ATOM   16045 O O     . ASP E 1 375 ? -54.099  -13.454  -59.054 1.00 27.74  ? 375  ASP E O     1 
ATOM   16046 C CB    . ASP E 1 375 ? -56.854  -12.698  -57.805 1.00 26.68  ? 375  ASP E CB    1 
ATOM   16047 C CG    . ASP E 1 375 ? -57.997  -13.487  -58.437 1.00 28.00  ? 375  ASP E CG    1 
ATOM   16048 O OD1   . ASP E 1 375 ? -58.986  -12.819  -58.831 1.00 26.02  ? 375  ASP E OD1   1 
ATOM   16049 O OD2   . ASP E 1 375 ? -57.867  -14.754  -58.584 1.00 22.68  ? 375  ASP E OD2   1 
ATOM   16050 N N     . ASN E 1 376 ? -55.552  -13.483  -60.762 1.00 28.46  ? 376  ASN E N     1 
ATOM   16051 C CA    . ASN E 1 376 ? -54.818  -14.562  -61.403 1.00 27.93  ? 376  ASN E CA    1 
ATOM   16052 C C     . ASN E 1 376 ? -54.789  -14.401  -62.922 1.00 28.56  ? 376  ASN E C     1 
ATOM   16053 O O     . ASN E 1 376 ? -54.330  -15.301  -63.614 1.00 30.33  ? 376  ASN E O     1 
ATOM   16054 C CB    . ASN E 1 376 ? -55.361  -15.945  -61.029 1.00 29.05  ? 376  ASN E CB    1 
ATOM   16055 C CG    . ASN E 1 376 ? -56.737  -16.209  -61.617 1.00 29.67  ? 376  ASN E CG    1 
ATOM   16056 O OD1   . ASN E 1 376 ? -57.373  -15.314  -62.202 1.00 24.90  ? 376  ASN E OD1   1 
ATOM   16057 N ND2   . ASN E 1 376 ? -57.234  -17.427  -61.464 1.00 26.28  ? 376  ASN E ND2   1 
ATOM   16058 N N     . ASP E 1 377 ? -55.332  -13.304  -63.458 1.00 28.66  ? 377  ASP E N     1 
ATOM   16059 C CA    . ASP E 1 377 ? -55.300  -13.044  -64.894 1.00 37.39  ? 377  ASP E CA    1 
ATOM   16060 C C     . ASP E 1 377 ? -56.170  -13.989  -65.733 1.00 36.54  ? 377  ASP E C     1 
ATOM   16061 O O     . ASP E 1 377 ? -56.048  -13.977  -66.947 1.00 36.25  ? 377  ASP E O     1 
ATOM   16062 C CB    . ASP E 1 377 ? -53.886  -12.930  -65.457 1.00 36.85  ? 377  ASP E CB    1 
ATOM   16063 C CG    . ASP E 1 377 ? -53.104  -11.726  -64.941 1.00 50.91  ? 377  ASP E CG    1 
ATOM   16064 O OD1   . ASP E 1 377 ? -53.681  -10.601  -64.873 1.00 60.48  ? 377  ASP E OD1   1 
ATOM   16065 O OD2   . ASP E 1 377 ? -51.928  -11.918  -64.587 1.00 56.55  ? 377  ASP E OD2   1 
ATOM   16066 N N     . GLU E 1 378 ? -57.035  -14.807  -65.131 1.00 32.42  ? 378  GLU E N     1 
ATOM   16067 C CA    . GLU E 1 378 ? -57.903  -15.642  -65.944 1.00 30.05  ? 378  GLU E CA    1 
ATOM   16068 C C     . GLU E 1 378 ? -58.819  -14.764  -66.798 1.00 30.71  ? 378  GLU E C     1 
ATOM   16069 O O     . GLU E 1 378 ? -59.378  -13.781  -66.314 1.00 31.42  ? 378  GLU E O     1 
ATOM   16070 C CB    . GLU E 1 378 ? -58.677  -16.610  -65.056 1.00 30.54  ? 378  GLU E CB    1 
ATOM   16071 C CG    . GLU E 1 378 ? -59.625  -17.511  -65.839 1.00 33.58  ? 378  GLU E CG    1 
ATOM   16072 C CD    . GLU E 1 378 ? -60.697  -18.174  -64.980 1.00 36.59  ? 378  GLU E CD    1 
ATOM   16073 O OE1   . GLU E 1 378 ? -60.793  -17.893  -63.786 1.00 37.15  ? 378  GLU E OE1   1 
ATOM   16074 O OE2   . GLU E 1 378 ? -61.446  -19.010  -65.491 1.00 39.99  ? 378  GLU E OE2   1 
ATOM   16075 N N     . VAL E 1 379 ? -58.947  -15.114  -68.088 1.00 29.35  ? 379  VAL E N     1 
ATOM   16076 C CA    . VAL E 1 379 ? -59.810  -14.397  -69.018 1.00 30.18  ? 379  VAL E CA    1 
ATOM   16077 C C     . VAL E 1 379 ? -61.237  -14.921  -68.865 1.00 28.90  ? 379  VAL E C     1 
ATOM   16078 O O     . VAL E 1 379 ? -61.441  -16.134  -68.819 1.00 27.38  ? 379  VAL E O     1 
ATOM   16079 C CB    . VAL E 1 379 ? -59.273  -14.648  -70.442 1.00 30.14  ? 379  VAL E CB    1 
ATOM   16080 C CG1   . VAL E 1 379 ? -60.256  -14.201  -71.513 1.00 27.78  ? 379  VAL E CG1   1 
ATOM   16081 C CG2   . VAL E 1 379 ? -57.960  -13.907  -70.630 1.00 27.02  ? 379  VAL E CG2   1 
ATOM   16082 N N     . LEU E 1 380 ? -62.211  -14.006  -68.814 1.00 25.61  ? 380  LEU E N     1 
ATOM   16083 C CA    . LEU E 1 380 ? -63.600  -14.383  -68.579 1.00 27.83  ? 380  LEU E CA    1 
ATOM   16084 C C     . LEU E 1 380 ? -64.345  -14.385  -69.905 1.00 30.12  ? 380  LEU E C     1 
ATOM   16085 O O     . LEU E 1 380 ? -64.112  -13.513  -70.751 1.00 29.48  ? 380  LEU E O     1 
ATOM   16086 C CB    . LEU E 1 380 ? -64.266  -13.397  -67.613 1.00 26.92  ? 380  LEU E CB    1 
ATOM   16087 C CG    . LEU E 1 380 ? -63.595  -13.184  -66.240 1.00 29.98  ? 380  LEU E CG    1 
ATOM   16088 C CD1   . LEU E 1 380 ? -64.614  -12.524  -65.321 1.00 29.64  ? 380  LEU E CD1   1 
ATOM   16089 C CD2   . LEU E 1 380 ? -63.255  -14.566  -65.758 1.00 32.16  ? 380  LEU E CD2   1 
ATOM   16090 N N     . SER E 1 381 ? -65.303  -15.300  -70.069 1.00 25.84  ? 381  SER E N     1 
ATOM   16091 C CA    . SER E 1 381 ? -66.146  -15.152  -71.249 1.00 28.09  ? 381  SER E CA    1 
ATOM   16092 C C     . SER E 1 381 ? -67.276  -14.160  -70.951 1.00 28.72  ? 381  SER E C     1 
ATOM   16093 O O     . SER E 1 381 ? -67.664  -13.980  -69.783 1.00 30.98  ? 381  SER E O     1 
ATOM   16094 C CB    . SER E 1 381 ? -66.633  -16.476  -71.733 1.00 25.84  ? 381  SER E CB    1 
ATOM   16095 O OG    . SER E 1 381 ? -67.332  -17.141  -70.699 1.00 32.90  ? 381  SER E OG    1 
ATOM   16096 N N     . PHE E 1 382 ? -67.790  -13.499  -71.996 1.00 26.26  ? 382  PHE E N     1 
ATOM   16097 C CA    . PHE E 1 382 ? -68.834  -12.506  -71.820 1.00 29.35  ? 382  PHE E CA    1 
ATOM   16098 C C     . PHE E 1 382 ? -69.678  -12.398  -73.096 1.00 29.31  ? 382  PHE E C     1 
ATOM   16099 O O     . PHE E 1 382 ? -69.256  -12.828  -74.154 1.00 30.87  ? 382  PHE E O     1 
ATOM   16100 C CB    . PHE E 1 382 ? -68.156  -11.176  -71.449 1.00 27.92  ? 382  PHE E CB    1 
ATOM   16101 C CG    . PHE E 1 382 ? -67.334  -10.568  -72.580 1.00 25.01  ? 382  PHE E CG    1 
ATOM   16102 C CD1   . PHE E 1 382 ? -65.993  -10.917  -72.756 1.00 25.49  ? 382  PHE E CD1   1 
ATOM   16103 C CD2   . PHE E 1 382 ? -67.916  -9.677   -73.481 1.00 28.82  ? 382  PHE E CD2   1 
ATOM   16104 C CE1   . PHE E 1 382 ? -65.227  -10.349  -73.783 1.00 28.90  ? 382  PHE E CE1   1 
ATOM   16105 C CE2   . PHE E 1 382 ? -67.166  -9.137   -74.531 1.00 27.48  ? 382  PHE E CE2   1 
ATOM   16106 C CZ    . PHE E 1 382 ? -65.823  -9.473   -74.681 1.00 27.18  ? 382  PHE E CZ    1 
ATOM   16107 N N     . THR E 1 383 ? -70.867  -11.797  -72.984 1.00 27.26  ? 383  THR E N     1 
ATOM   16108 C CA    . THR E 1 383 ? -71.697  -11.392  -74.102 1.00 28.03  ? 383  THR E CA    1 
ATOM   16109 C C     . THR E 1 383 ? -72.124  -9.946   -73.823 1.00 28.89  ? 383  THR E C     1 
ATOM   16110 O O     . THR E 1 383 ? -72.207  -9.526   -72.670 1.00 29.30  ? 383  THR E O     1 
ATOM   16111 C CB    . THR E 1 383 ? -72.935  -12.286  -74.255 1.00 29.36  ? 383  THR E CB    1 
ATOM   16112 O OG1   . THR E 1 383 ? -73.702  -12.131  -73.053 1.00 33.68  ? 383  THR E OG1   1 
ATOM   16113 C CG2   . THR E 1 383 ? -72.631  -13.761  -74.439 1.00 26.91  ? 383  THR E CG2   1 
ATOM   16114 N N     . GLN E 1 384 ? -72.422  -9.203   -74.890 1.00 27.82  ? 384  GLN E N     1 
ATOM   16115 C CA    . GLN E 1 384 ? -72.946  -7.864   -74.775 1.00 30.79  ? 384  GLN E CA    1 
ATOM   16116 C C     . GLN E 1 384 ? -74.205  -7.728   -75.620 1.00 32.61  ? 384  GLN E C     1 
ATOM   16117 O O     . GLN E 1 384 ? -74.313  -8.345   -76.662 1.00 32.97  ? 384  GLN E O     1 
ATOM   16118 C CB    . GLN E 1 384 ? -71.940  -6.826   -75.280 1.00 27.18  ? 384  GLN E CB    1 
ATOM   16119 C CG    . GLN E 1 384 ? -70.681  -6.803   -74.426 1.00 26.88  ? 384  GLN E CG    1 
ATOM   16120 C CD    . GLN E 1 384 ? -69.728  -5.695   -74.769 1.00 30.01  ? 384  GLN E CD    1 
ATOM   16121 O OE1   . GLN E 1 384 ? -68.779  -5.890   -75.534 1.00 34.37  ? 384  GLN E OE1   1 
ATOM   16122 N NE2   . GLN E 1 384 ? -69.963  -4.528   -74.197 1.00 28.74  ? 384  GLN E NE2   1 
ATOM   16123 N N     . ASP E 1 385 ? -75.135  -6.887   -75.156 1.00 31.70  ? 385  ASP E N     1 
ATOM   16124 C CA    . ASP E 1 385 ? -76.130  -6.260   -76.007 1.00 31.25  ? 385  ASP E CA    1 
ATOM   16125 C C     . ASP E 1 385 ? -75.874  -4.754   -75.966 1.00 34.29  ? 385  ASP E C     1 
ATOM   16126 O O     . ASP E 1 385 ? -76.231  -4.093   -74.983 1.00 31.47  ? 385  ASP E O     1 
ATOM   16127 C CB    . ASP E 1 385 ? -77.536  -6.629   -75.559 1.00 32.69  ? 385  ASP E CB    1 
ATOM   16128 C CG    . ASP E 1 385 ? -78.665  -5.905   -76.287 1.00 43.73  ? 385  ASP E CG    1 
ATOM   16129 O OD1   . ASP E 1 385 ? -78.380  -4.878   -76.952 1.00 44.73  ? 385  ASP E OD1   1 
ATOM   16130 O OD2   . ASP E 1 385 ? -79.839  -6.369   -76.195 1.00 52.88  ? 385  ASP E OD2   1 
ATOM   16131 N N     . LEU E 1 386 ? -75.239  -4.234   -77.023 1.00 34.22  ? 386  LEU E N     1 
ATOM   16132 C CA    . LEU E 1 386 ? -74.815  -2.841   -77.053 1.00 35.17  ? 386  LEU E CA    1 
ATOM   16133 C C     . LEU E 1 386 ? -76.000  -1.879   -77.067 1.00 35.32  ? 386  LEU E C     1 
ATOM   16134 O O     . LEU E 1 386 ? -75.912  -0.823   -76.457 1.00 40.15  ? 386  LEU E O     1 
ATOM   16135 C CB    . LEU E 1 386 ? -73.809  -2.549   -78.158 1.00 36.94  ? 386  LEU E CB    1 
ATOM   16136 C CG    . LEU E 1 386 ? -72.521  -3.383   -78.053 1.00 44.14  ? 386  LEU E CG    1 
ATOM   16137 C CD1   . LEU E 1 386 ? -71.655  -3.305   -79.303 1.00 42.48  ? 386  LEU E CD1   1 
ATOM   16138 C CD2   . LEU E 1 386 ? -71.705  -2.967   -76.828 1.00 42.69  ? 386  LEU E CD2   1 
ATOM   16139 N N     . ASP E 1 387 ? -77.125  -2.259   -77.672 1.00 37.46  ? 387  ASP E N     1 
ATOM   16140 C CA    . ASP E 1 387 ? -78.262  -1.342   -77.723 1.00 37.33  ? 387  ASP E CA    1 
ATOM   16141 C C     . ASP E 1 387 ? -78.846  -1.127   -76.330 1.00 38.21  ? 387  ASP E C     1 
ATOM   16142 O O     . ASP E 1 387 ? -79.204  0.005    -75.981 1.00 34.69  ? 387  ASP E O     1 
ATOM   16143 C CB    . ASP E 1 387 ? -79.355  -1.749   -78.698 1.00 50.89  ? 387  ASP E CB    1 
ATOM   16144 C CG    . ASP E 1 387 ? -78.856  -2.090   -80.092 1.00 73.10  ? 387  ASP E CG    1 
ATOM   16145 O OD1   . ASP E 1 387 ? -78.173  -1.230   -80.694 1.00 73.20  ? 387  ASP E OD1   1 
ATOM   16146 O OD2   . ASP E 1 387 ? -79.128  -3.222   -80.543 1.00 86.94  ? 387  ASP E OD2   1 
ATOM   16147 N N     . LYS E 1 388 ? -78.940  -2.203   -75.529 1.00 35.74  ? 388  LYS E N     1 
ATOM   16148 C CA    . LYS E 1 388 ? -79.551  -2.096   -74.219 1.00 33.35  ? 388  LYS E CA    1 
ATOM   16149 C C     . LYS E 1 388 ? -78.482  -1.868   -73.146 1.00 34.17  ? 388  LYS E C     1 
ATOM   16150 O O     . LYS E 1 388 ? -78.823  -1.634   -71.989 1.00 32.71  ? 388  LYS E O     1 
ATOM   16151 C CB    . LYS E 1 388 ? -80.494  -3.283   -74.036 1.00 32.07  ? 388  LYS E CB    1 
ATOM   16152 C CG    . LYS E 1 388 ? -81.842  -2.902   -74.607 1.00 31.66  ? 388  LYS E CG    1 
ATOM   16153 C CD    . LYS E 1 388 ? -82.844  -4.032   -74.561 1.00 27.17  ? 388  LYS E CD    1 
ATOM   16154 C CE    . LYS E 1 388 ? -84.211  -3.488   -74.903 1.00 28.44  ? 388  LYS E CE    1 
ATOM   16155 N NZ    . LYS E 1 388 ? -85.144  -4.629   -74.786 1.00 31.71  ? 388  LYS E NZ    1 
ATOM   16156 N N     . LYS E 1 389 ? -77.205  -1.916   -73.554 1.00 27.91  ? 389  LYS E N     1 
ATOM   16157 C CA    . LYS E 1 389 ? -76.081  -1.645   -72.679 1.00 32.97  ? 389  LYS E CA    1 
ATOM   16158 C C     . LYS E 1 389 ? -75.971  -2.734   -71.600 1.00 32.56  ? 389  LYS E C     1 
ATOM   16159 O O     . LYS E 1 389 ? -75.694  -2.443   -70.430 1.00 26.77  ? 389  LYS E O     1 
ATOM   16160 C CB    . LYS E 1 389 ? -76.115  -0.216   -72.114 1.00 35.53  ? 389  LYS E CB    1 
ATOM   16161 C CG    . LYS E 1 389 ? -76.185  0.902    -73.149 1.00 46.79  ? 389  LYS E CG    1 
ATOM   16162 C CD    . LYS E 1 389 ? -76.414  2.218    -72.428 1.00 56.58  ? 389  LYS E CD    1 
ATOM   16163 C CE    . LYS E 1 389 ? -76.762  3.379    -73.296 1.00 62.81  ? 389  LYS E CE    1 
ATOM   16164 N NZ    . LYS E 1 389 ? -75.478  3.962    -73.672 1.00 66.58  ? 389  LYS E NZ    1 
ATOM   16165 N N     . VAL E 1 390 ? -76.118  -3.990   -72.025 1.00 27.54  ? 390  VAL E N     1 
ATOM   16166 C CA    . VAL E 1 390 ? -76.045  -5.124   -71.121 1.00 25.75  ? 390  VAL E CA    1 
ATOM   16167 C C     . VAL E 1 390 ? -74.717  -5.839   -71.327 1.00 28.35  ? 390  VAL E C     1 
ATOM   16168 O O     . VAL E 1 390 ? -74.342  -6.134   -72.465 1.00 30.93  ? 390  VAL E O     1 
ATOM   16169 C CB    . VAL E 1 390 ? -77.222  -6.114   -71.279 1.00 25.37  ? 390  VAL E CB    1 
ATOM   16170 C CG1   . VAL E 1 390 ? -77.080  -7.323   -70.366 1.00 20.96  ? 390  VAL E CG1   1 
ATOM   16171 C CG2   . VAL E 1 390 ? -78.576  -5.434   -71.093 1.00 24.23  ? 390  VAL E CG2   1 
ATOM   16172 N N     . LEU E 1 391 ? -74.031  -6.119   -70.204 1.00 24.52  ? 391  LEU E N     1 
ATOM   16173 C CA    . LEU E 1 391 ? -72.879  -7.000   -70.171 1.00 23.38  ? 391  LEU E CA    1 
ATOM   16174 C C     . LEU E 1 391 ? -73.191  -8.186   -69.251 1.00 26.04  ? 391  LEU E C     1 
ATOM   16175 O O     . LEU E 1 391 ? -73.687  -7.994   -68.128 1.00 29.90  ? 391  LEU E O     1 
ATOM   16176 C CB    . LEU E 1 391 ? -71.710  -6.178   -69.628 1.00 20.54  ? 391  LEU E CB    1 
ATOM   16177 C CG    . LEU E 1 391 ? -70.450  -6.986   -69.291 1.00 21.13  ? 391  LEU E CG    1 
ATOM   16178 C CD1   . LEU E 1 391 ? -69.877  -7.658   -70.549 1.00 19.38  ? 391  LEU E CD1   1 
ATOM   16179 C CD2   . LEU E 1 391 ? -69.388  -6.153   -68.603 1.00 19.62  ? 391  LEU E CD2   1 
ATOM   16180 N N     . THR E 1 392 ? -72.886  -9.405   -69.721 1.00 23.38  ? 392  THR E N     1 
ATOM   16181 C CA    . THR E 1 392 ? -73.014  -10.599  -68.899 1.00 22.60  ? 392  THR E CA    1 
ATOM   16182 C C     . THR E 1 392 ? -71.675  -11.326  -68.942 1.00 26.48  ? 392  THR E C     1 
ATOM   16183 O O     . THR E 1 392 ? -71.214  -11.631  -70.039 1.00 26.96  ? 392  THR E O     1 
ATOM   16184 C CB    . THR E 1 392 ? -74.113  -11.525  -69.412 1.00 21.90  ? 392  THR E CB    1 
ATOM   16185 O OG1   . THR E 1 392 ? -75.328  -10.792  -69.407 1.00 22.16  ? 392  THR E OG1   1 
ATOM   16186 C CG2   . THR E 1 392 ? -74.308  -12.735  -68.514 1.00 20.15  ? 392  THR E CG2   1 
ATOM   16187 N N     . VAL E 1 393 ? -71.072  -11.598  -67.761 1.00 24.50  ? 393  VAL E N     1 
ATOM   16188 C CA    . VAL E 1 393 ? -69.828  -12.345  -67.699 1.00 22.17  ? 393  VAL E CA    1 
ATOM   16189 C C     . VAL E 1 393 ? -70.107  -13.659  -66.976 1.00 24.75  ? 393  VAL E C     1 
ATOM   16190 O O     . VAL E 1 393 ? -71.016  -13.738  -66.138 1.00 22.51  ? 393  VAL E O     1 
ATOM   16191 C CB    . VAL E 1 393 ? -68.708  -11.594  -66.966 1.00 23.66  ? 393  VAL E CB    1 
ATOM   16192 C CG1   . VAL E 1 393 ? -68.512  -10.206  -67.532 1.00 23.07  ? 393  VAL E CG1   1 
ATOM   16193 C CG2   . VAL E 1 393 ? -69.028  -11.478  -65.479 1.00 25.00  ? 393  VAL E CG2   1 
ATOM   16194 N N     . ASP E 1 394 ? -69.324  -14.686  -67.314 1.00 25.44  ? 394  ASP E N     1 
ATOM   16195 C CA    . ASP E 1 394 ? -69.308  -15.895  -66.508 1.00 25.33  ? 394  ASP E CA    1 
ATOM   16196 C C     . ASP E 1 394 ? -68.261  -15.689  -65.407 1.00 26.49  ? 394  ASP E C     1 
ATOM   16197 O O     . ASP E 1 394 ? -67.047  -15.805  -65.674 1.00 22.26  ? 394  ASP E O     1 
ATOM   16198 C CB    . ASP E 1 394 ? -68.990  -17.142  -67.315 1.00 22.45  ? 394  ASP E CB    1 
ATOM   16199 C CG    . ASP E 1 394 ? -68.748  -18.399  -66.473 1.00 28.75  ? 394  ASP E CG    1 
ATOM   16200 O OD1   . ASP E 1 394 ? -69.173  -18.416  -65.269 1.00 27.42  ? 394  ASP E OD1   1 
ATOM   16201 O OD2   . ASP E 1 394 ? -68.138  -19.378  -67.003 1.00 30.66  ? 394  ASP E OD2   1 
ATOM   16202 N N     . ALA E 1 395 ? -68.735  -15.356  -64.189 1.00 22.17  ? 395  ALA E N     1 
ATOM   16203 C CA    . ALA E 1 395 ? -67.816  -15.035  -63.104 1.00 19.99  ? 395  ALA E CA    1 
ATOM   16204 C C     . ALA E 1 395 ? -67.375  -16.333  -62.428 1.00 20.70  ? 395  ALA E C     1 
ATOM   16205 O O     . ALA E 1 395 ? -68.060  -16.834  -61.537 1.00 20.52  ? 395  ALA E O     1 
ATOM   16206 C CB    . ALA E 1 395 ? -68.479  -14.075  -62.132 1.00 17.72  ? 395  ALA E CB    1 
ATOM   16207 N N     . THR E 1 396 ? -66.261  -16.901  -62.883 1.00 21.58  ? 396  THR E N     1 
ATOM   16208 C CA    . THR E 1 396 ? -65.799  -18.180  -62.359 1.00 24.77  ? 396  THR E CA    1 
ATOM   16209 C C     . THR E 1 396 ? -65.433  -18.033  -60.880 1.00 25.73  ? 396  THR E C     1 
ATOM   16210 O O     . THR E 1 396 ? -65.075  -16.950  -60.411 1.00 24.67  ? 396  THR E O     1 
ATOM   16211 C CB    . THR E 1 396 ? -64.621  -18.679  -63.209 1.00 27.25  ? 396  THR E CB    1 
ATOM   16212 O OG1   . THR E 1 396 ? -63.656  -17.621  -63.252 1.00 25.21  ? 396  THR E OG1   1 
ATOM   16213 C CG2   . THR E 1 396 ? -65.035  -19.025  -64.635 1.00 21.43  ? 396  THR E CG2   1 
ATOM   16214 N N     . GLY E 1 397 ? -65.544  -19.137  -60.140 1.00 23.82  ? 397  GLY E N     1 
ATOM   16215 C CA    . GLY E 1 397 ? -65.270  -19.180  -58.722 1.00 21.10  ? 397  GLY E CA    1 
ATOM   16216 C C     . GLY E 1 397 ? -63.769  -19.169  -58.442 1.00 23.63  ? 397  GLY E C     1 
ATOM   16217 O O     . GLY E 1 397 ? -62.945  -19.194  -59.356 1.00 24.39  ? 397  GLY E O     1 
ATOM   16218 N N     . TYR E 1 398 ? -63.412  -19.102  -57.151 1.00 24.52  ? 398  TYR E N     1 
ATOM   16219 C CA    . TYR E 1 398 ? -62.014  -18.969  -56.770 1.00 24.79  ? 398  TYR E CA    1 
ATOM   16220 C C     . TYR E 1 398 ? -61.262  -20.264  -57.045 1.00 25.13  ? 398  TYR E C     1 
ATOM   16221 O O     . TYR E 1 398 ? -61.780  -21.353  -56.796 1.00 27.52  ? 398  TYR E O     1 
ATOM   16222 C CB    . TYR E 1 398 ? -61.895  -18.632  -55.285 1.00 23.53  ? 398  TYR E CB    1 
ATOM   16223 C CG    . TYR E 1 398 ? -62.594  -17.333  -54.920 1.00 24.99  ? 398  TYR E CG    1 
ATOM   16224 C CD1   . TYR E 1 398 ? -62.089  -16.122  -55.392 1.00 23.86  ? 398  TYR E CD1   1 
ATOM   16225 C CD2   . TYR E 1 398 ? -63.736  -17.312  -54.107 1.00 23.17  ? 398  TYR E CD2   1 
ATOM   16226 C CE1   . TYR E 1 398 ? -62.705  -14.920  -55.084 1.00 19.60  ? 398  TYR E CE1   1 
ATOM   16227 C CE2   . TYR E 1 398 ? -64.349  -16.106  -53.776 1.00 23.41  ? 398  TYR E CE2   1 
ATOM   16228 C CZ    . TYR E 1 398 ? -63.814  -14.917  -54.271 1.00 23.43  ? 398  TYR E CZ    1 
ATOM   16229 O OH    . TYR E 1 398 ? -64.355  -13.700  -54.034 1.00 25.79  ? 398  TYR E OH    1 
ATOM   16230 N N     . PRO E 1 399 ? -59.991  -20.193  -57.482 1.00 23.69  ? 399  PRO E N     1 
ATOM   16231 C CA    . PRO E 1 399 ? -59.124  -21.368  -57.414 1.00 24.91  ? 399  PRO E CA    1 
ATOM   16232 C C     . PRO E 1 399 ? -59.061  -21.900  -55.981 1.00 24.63  ? 399  PRO E C     1 
ATOM   16233 O O     . PRO E 1 399 ? -58.981  -21.128  -55.014 1.00 23.29  ? 399  PRO E O     1 
ATOM   16234 C CB    . PRO E 1 399 ? -57.725  -20.875  -57.811 1.00 23.45  ? 399  PRO E CB    1 
ATOM   16235 C CG    . PRO E 1 399 ? -57.953  -19.501  -58.385 1.00 26.68  ? 399  PRO E CG    1 
ATOM   16236 C CD    . PRO E 1 399 ? -59.308  -18.974  -57.935 1.00 25.68  ? 399  PRO E CD    1 
ATOM   16237 N N     . TYR E 1 400 ? -59.127  -23.220  -55.845 1.00 21.46  ? 400  TYR E N     1 
ATOM   16238 C CA    . TYR E 1 400 ? -59.015  -23.842  -54.545 1.00 20.35  ? 400  TYR E CA    1 
ATOM   16239 C C     . TYR E 1 400 ? -57.799  -23.254  -53.836 1.00 22.11  ? 400  TYR E C     1 
ATOM   16240 O O     . TYR E 1 400 ? -56.745  -23.045  -54.456 1.00 23.34  ? 400  TYR E O     1 
ATOM   16241 C CB    . TYR E 1 400 ? -58.938  -25.360  -54.707 1.00 18.31  ? 400  TYR E CB    1 
ATOM   16242 C CG    . TYR E 1 400 ? -58.727  -26.052  -53.367 1.00 20.80  ? 400  TYR E CG    1 
ATOM   16243 C CD1   . TYR E 1 400 ? -59.783  -26.255  -52.487 1.00 19.70  ? 400  TYR E CD1   1 
ATOM   16244 C CD2   . TYR E 1 400 ? -57.449  -26.460  -52.970 1.00 19.80  ? 400  TYR E CD2   1 
ATOM   16245 C CE1   . TYR E 1 400 ? -59.586  -26.866  -51.251 1.00 22.18  ? 400  TYR E CE1   1 
ATOM   16246 C CE2   . TYR E 1 400 ? -57.241  -27.091  -51.746 1.00 20.87  ? 400  TYR E CE2   1 
ATOM   16247 C CZ    . TYR E 1 400 ? -58.309  -27.286  -50.886 1.00 22.94  ? 400  TYR E CZ    1 
ATOM   16248 O OH    . TYR E 1 400 ? -58.090  -27.904  -49.695 1.00 23.27  ? 400  TYR E OH    1 
ATOM   16249 N N     . GLY E 1 401 ? -57.960  -22.970  -52.542 1.00 21.80  ? 401  GLY E N     1 
ATOM   16250 C CA    . GLY E 1 401 ? -56.834  -22.437  -51.786 1.00 23.33  ? 401  GLY E CA    1 
ATOM   16251 C C     . GLY E 1 401 ? -56.864  -20.916  -51.699 1.00 24.73  ? 401  GLY E C     1 
ATOM   16252 O O     . GLY E 1 401 ? -56.063  -20.306  -50.979 1.00 25.69  ? 401  GLY E O     1 
ATOM   16253 N N     . SER E 1 402 ? -57.833  -20.282  -52.360 1.00 24.00  ? 402  SER E N     1 
ATOM   16254 C CA    . SER E 1 402 ? -57.868  -18.832  -52.236 1.00 25.51  ? 402  SER E CA    1 
ATOM   16255 C C     . SER E 1 402 ? -59.323  -18.342  -52.212 1.00 26.85  ? 402  SER E C     1 
ATOM   16256 O O     . SER E 1 402 ? -60.249  -19.094  -52.535 1.00 27.33  ? 402  SER E O     1 
ATOM   16257 C CB    . SER E 1 402 ? -57.004  -18.199  -53.312 1.00 24.77  ? 402  SER E CB    1 
ATOM   16258 O OG    . SER E 1 402 ? -57.738  -18.266  -54.523 1.00 37.88  ? 402  SER E OG    1 
ATOM   16259 N N     . ASP E 1 403 ? -59.538  -17.125  -51.708 1.00 26.76  ? 403  ASP E N     1 
ATOM   16260 C CA    . ASP E 1 403 ? -60.879  -16.554  -51.582 1.00 25.69  ? 403  ASP E CA    1 
ATOM   16261 C C     . ASP E 1 403 ? -60.720  -15.067  -51.249 1.00 29.26  ? 403  ASP E C     1 
ATOM   16262 O O     . ASP E 1 403 ? -60.303  -14.713  -50.148 1.00 23.42  ? 403  ASP E O     1 
ATOM   16263 C CB    . ASP E 1 403 ? -61.710  -17.296  -50.546 1.00 23.88  ? 403  ASP E CB    1 
ATOM   16264 C CG    . ASP E 1 403 ? -63.163  -16.844  -50.412 1.00 28.25  ? 403  ASP E CG    1 
ATOM   16265 O OD1   . ASP E 1 403 ? -63.455  -15.670  -50.773 1.00 28.56  ? 403  ASP E OD1   1 
ATOM   16266 O OD2   . ASP E 1 403 ? -64.023  -17.682  -49.989 1.00 26.13  ? 403  ASP E OD2   1 
ATOM   16267 N N     . TRP E 1 404 ? -61.049  -14.209  -52.232 1.00 26.23  ? 404  TRP E N     1 
ATOM   16268 C CA    . TRP E 1 404 ? -60.735  -12.783  -52.172 1.00 24.80  ? 404  TRP E CA    1 
ATOM   16269 C C     . TRP E 1 404 ? -61.873  -11.966  -51.570 1.00 23.00  ? 404  TRP E C     1 
ATOM   16270 O O     . TRP E 1 404 ? -61.721  -10.768  -51.366 1.00 24.37  ? 404  TRP E O     1 
ATOM   16271 C CB    . TRP E 1 404 ? -60.313  -12.259  -53.559 1.00 22.19  ? 404  TRP E CB    1 
ATOM   16272 C CG    . TRP E 1 404 ? -59.002  -12.868  -54.005 1.00 25.74  ? 404  TRP E CG    1 
ATOM   16273 C CD1   . TRP E 1 404 ? -58.849  -14.000  -54.759 1.00 24.61  ? 404  TRP E CD1   1 
ATOM   16274 C CD2   . TRP E 1 404 ? -57.663  -12.434  -53.652 1.00 24.04  ? 404  TRP E CD2   1 
ATOM   16275 N NE1   . TRP E 1 404 ? -57.521  -14.287  -54.920 1.00 26.89  ? 404  TRP E NE1   1 
ATOM   16276 C CE2   . TRP E 1 404 ? -56.767  -13.350  -54.256 1.00 26.75  ? 404  TRP E CE2   1 
ATOM   16277 C CE3   . TRP E 1 404 ? -57.142  -11.368  -52.903 1.00 25.07  ? 404  TRP E CE3   1 
ATOM   16278 C CZ2   . TRP E 1 404 ? -55.381  -13.216  -54.158 1.00 24.01  ? 404  TRP E CZ2   1 
ATOM   16279 C CZ3   . TRP E 1 404 ? -55.766  -11.241  -52.798 1.00 27.70  ? 404  TRP E CZ3   1 
ATOM   16280 C CH2   . TRP E 1 404 ? -54.897  -12.159  -53.418 1.00 25.49  ? 404  TRP E CH2   1 
ATOM   16281 N N     . VAL E 1 405 ? -63.031  -12.604  -51.342 1.00 20.14  ? 405  VAL E N     1 
ATOM   16282 C CA    . VAL E 1 405 ? -64.200  -11.946  -50.778 1.00 18.43  ? 405  VAL E CA    1 
ATOM   16283 C C     . VAL E 1 405 ? -64.847  -10.989  -51.781 1.00 20.69  ? 405  VAL E C     1 
ATOM   16284 O O     . VAL E 1 405 ? -66.041  -11.123  -52.073 1.00 19.66  ? 405  VAL E O     1 
ATOM   16285 C CB    . VAL E 1 405 ? -63.975  -11.252  -49.421 1.00 16.50  ? 405  VAL E CB    1 
ATOM   16286 C CG1   . VAL E 1 405 ? -65.270  -10.615  -48.901 1.00 14.67  ? 405  VAL E CG1   1 
ATOM   16287 C CG2   . VAL E 1 405 ? -63.374  -12.223  -48.405 1.00 16.21  ? 405  VAL E CG2   1 
ATOM   16288 N N     . VAL E 1 406 ? -64.107  -9.957   -52.217 1.00 19.53  ? 406  VAL E N     1 
ATOM   16289 C CA    . VAL E 1 406 ? -64.570  -9.122   -53.314 1.00 19.70  ? 406  VAL E CA    1 
ATOM   16290 C C     . VAL E 1 406 ? -63.582  -9.342   -54.458 1.00 21.50  ? 406  VAL E C     1 
ATOM   16291 O O     . VAL E 1 406 ? -62.405  -8.979   -54.323 1.00 19.04  ? 406  VAL E O     1 
ATOM   16292 C CB    . VAL E 1 406 ? -64.629  -7.622   -52.946 1.00 19.73  ? 406  VAL E CB    1 
ATOM   16293 C CG1   . VAL E 1 406 ? -64.965  -6.749   -54.144 1.00 17.64  ? 406  VAL E CG1   1 
ATOM   16294 C CG2   . VAL E 1 406 ? -65.626  -7.331   -51.834 1.00 17.89  ? 406  VAL E CG2   1 
ATOM   16295 N N     . ARG E 1 407 ? -64.051  -9.978   -55.553 1.00 19.32  ? 407  ARG E N     1 
ATOM   16296 C CA    . ARG E 1 407 ? -63.149  -10.309  -56.647 1.00 20.25  ? 407  ARG E CA    1 
ATOM   16297 C C     . ARG E 1 407 ? -63.300  -9.238   -57.728 1.00 22.26  ? 407  ARG E C     1 
ATOM   16298 O O     . ARG E 1 407 ? -64.414  -8.734   -57.940 1.00 24.45  ? 407  ARG E O     1 
ATOM   16299 C CB    . ARG E 1 407 ? -63.465  -11.696  -57.199 1.00 17.00  ? 407  ARG E CB    1 
ATOM   16300 C CG    . ARG E 1 407 ? -62.272  -12.390  -57.841 1.00 17.48  ? 407  ARG E CG    1 
ATOM   16301 C CD    . ARG E 1 407 ? -62.621  -13.725  -58.490 1.00 16.43  ? 407  ARG E CD    1 
ATOM   16302 N NE    . ARG E 1 407 ? -61.376  -14.349  -58.910 1.00 20.35  ? 407  ARG E NE    1 
ATOM   16303 C CZ    . ARG E 1 407 ? -61.259  -15.567  -59.449 1.00 23.69  ? 407  ARG E CZ    1 
ATOM   16304 N NH1   . ARG E 1 407 ? -62.336  -16.307  -59.694 1.00 23.32  ? 407  ARG E NH1   1 
ATOM   16305 N NH2   . ARG E 1 407 ? -60.051  -16.032  -59.745 1.00 20.33  ? 407  ARG E NH2   1 
ATOM   16306 N N     . ILE E 1 408 ? -62.189  -8.870   -58.392 1.00 22.40  ? 408  ILE E N     1 
ATOM   16307 C CA    . ILE E 1 408 ? -62.245  -7.721   -59.291 1.00 24.47  ? 408  ILE E CA    1 
ATOM   16308 C C     . ILE E 1 408 ? -61.807  -8.152   -60.691 1.00 24.94  ? 408  ILE E C     1 
ATOM   16309 O O     . ILE E 1 408 ? -60.710  -8.691   -60.869 1.00 24.46  ? 408  ILE E O     1 
ATOM   16310 C CB    . ILE E 1 408 ? -61.390  -6.558   -58.749 1.00 23.01  ? 408  ILE E CB    1 
ATOM   16311 C CG1   . ILE E 1 408 ? -61.853  -6.134   -57.341 1.00 20.59  ? 408  ILE E CG1   1 
ATOM   16312 C CG2   . ILE E 1 408 ? -61.398  -5.395   -59.737 1.00 22.19  ? 408  ILE E CG2   1 
ATOM   16313 C CD1   . ILE E 1 408 ? -61.002  -5.063   -56.682 1.00 20.55  ? 408  ILE E CD1   1 
ATOM   16314 N N     . ALA E 1 409 ? -62.663  -7.881   -61.677 1.00 23.04  ? 409  ALA E N     1 
ATOM   16315 C CA    . ALA E 1 409 ? -62.344  -8.160   -63.080 1.00 24.37  ? 409  ALA E CA    1 
ATOM   16316 C C     . ALA E 1 409 ? -62.107  -6.838   -63.809 1.00 23.58  ? 409  ALA E C     1 
ATOM   16317 O O     . ALA E 1 409 ? -62.935  -5.915   -63.708 1.00 26.88  ? 409  ALA E O     1 
ATOM   16318 C CB    . ALA E 1 409 ? -63.485  -8.940   -63.738 1.00 19.83  ? 409  ALA E CB    1 
ATOM   16319 N N     . GLN E 1 410 ? -60.980  -6.747   -64.521 1.00 25.03  ? 410  GLN E N     1 
ATOM   16320 C CA    . GLN E 1 410 ? -60.671  -5.562   -65.313 1.00 27.28  ? 410  GLN E CA    1 
ATOM   16321 C C     . GLN E 1 410 ? -61.208  -5.727   -66.740 1.00 26.50  ? 410  GLN E C     1 
ATOM   16322 O O     . GLN E 1 410 ? -60.996  -6.759   -67.379 1.00 28.18  ? 410  GLN E O     1 
ATOM   16323 C CB    . GLN E 1 410 ? -59.163  -5.402   -65.429 1.00 29.16  ? 410  GLN E CB    1 
ATOM   16324 C CG    . GLN E 1 410 ? -58.751  -4.134   -66.184 1.00 32.95  ? 410  GLN E CG    1 
ATOM   16325 C CD    . GLN E 1 410 ? -57.251  -3.950   -66.186 1.00 34.67  ? 410  GLN E CD    1 
ATOM   16326 O OE1   . GLN E 1 410 ? -56.623  -3.871   -65.124 1.00 38.13  ? 410  GLN E OE1   1 
ATOM   16327 N NE2   . GLN E 1 410 ? -56.661  -3.943   -67.371 1.00 30.63  ? 410  GLN E NE2   1 
ATOM   16328 N N     . ILE E 1 411 ? -61.913  -4.708   -67.211 1.00 27.02  ? 411  ILE E N     1 
ATOM   16329 C CA    . ILE E 1 411 ? -62.418  -4.626   -68.568 1.00 29.88  ? 411  ILE E CA    1 
ATOM   16330 C C     . ILE E 1 411 ? -61.437  -3.809   -69.424 1.00 33.46  ? 411  ILE E C     1 
ATOM   16331 O O     . ILE E 1 411 ? -61.118  -2.661   -69.088 1.00 33.57  ? 411  ILE E O     1 
ATOM   16332 C CB    . ILE E 1 411 ? -63.805  -3.969   -68.579 1.00 27.07  ? 411  ILE E CB    1 
ATOM   16333 C CG1   . ILE E 1 411 ? -64.844  -4.817   -67.869 1.00 28.07  ? 411  ILE E CG1   1 
ATOM   16334 C CG2   . ILE E 1 411 ? -64.213  -3.687   -70.017 1.00 26.53  ? 411  ILE E CG2   1 
ATOM   16335 C CD1   . ILE E 1 411 ? -66.203  -4.137   -67.640 1.00 26.17  ? 411  ILE E CD1   1 
ATOM   16336 N N     . ASP E 1 412 ? -60.992  -4.404   -70.546 1.00 31.17  ? 412  ASP E N     1 
ATOM   16337 C CA    . ASP E 1 412 ? -60.219  -3.739   -71.587 1.00 27.77  ? 412  ASP E CA    1 
ATOM   16338 C C     . ASP E 1 412 ? -61.129  -3.494   -72.782 1.00 32.97  ? 412  ASP E C     1 
ATOM   16339 O O     . ASP E 1 412 ? -61.638  -4.448   -73.386 1.00 34.95  ? 412  ASP E O     1 
ATOM   16340 C CB    . ASP E 1 412 ? -59.044  -4.606   -72.011 1.00 28.62  ? 412  ASP E CB    1 
ATOM   16341 C CG    . ASP E 1 412 ? -58.036  -4.873   -70.897 1.00 37.79  ? 412  ASP E CG    1 
ATOM   16342 O OD1   . ASP E 1 412 ? -58.082  -4.135   -69.873 1.00 43.15  ? 412  ASP E OD1   1 
ATOM   16343 O OD2   . ASP E 1 412 ? -57.262  -5.856   -71.023 1.00 40.83  ? 412  ASP E OD2   1 
ATOM   16344 N N     . TYR E 1 413 ? -61.358  -2.215   -73.095 1.00 34.41  ? 413  TYR E N     1 
ATOM   16345 C CA    . TYR E 1 413 ? -62.197  -1.853   -74.229 1.00 41.30  ? 413  TYR E CA    1 
ATOM   16346 C C     . TYR E 1 413 ? -61.422  -1.951   -75.541 1.00 50.70  ? 413  TYR E C     1 
ATOM   16347 O O     . TYR E 1 413 ? -60.196  -1.779   -75.577 1.00 45.46  ? 413  TYR E O     1 
ATOM   16348 C CB    . TYR E 1 413 ? -62.723  -0.433   -74.066 1.00 32.93  ? 413  TYR E CB    1 
ATOM   16349 C CG    . TYR E 1 413 ? -63.783  -0.427   -72.986 1.00 34.65  ? 413  TYR E CG    1 
ATOM   16350 C CD1   . TYR E 1 413 ? -65.037  -0.971   -73.231 1.00 34.35  ? 413  TYR E CD1   1 
ATOM   16351 C CD2   . TYR E 1 413 ? -63.514  0.085    -71.719 1.00 31.39  ? 413  TYR E CD2   1 
ATOM   16352 C CE1   . TYR E 1 413 ? -66.020  -0.963   -72.254 1.00 34.03  ? 413  TYR E CE1   1 
ATOM   16353 C CE2   . TYR E 1 413 ? -64.483  0.087    -70.733 1.00 31.98  ? 413  TYR E CE2   1 
ATOM   16354 C CZ    . TYR E 1 413 ? -65.734  -0.442   -70.998 1.00 34.73  ? 413  TYR E CZ    1 
ATOM   16355 O OH    . TYR E 1 413 ? -66.683  -0.434   -70.013 1.00 34.31  ? 413  TYR E OH    1 
ATOM   16356 N N     . GLU E 1 414 ? -62.180  -2.218   -76.618 1.00 55.38  ? 414  GLU E N     1 
ATOM   16357 C CA    . GLU E 1 414 ? -61.692  -2.060   -77.981 1.00 70.72  ? 414  GLU E CA    1 
ATOM   16358 C C     . GLU E 1 414 ? -61.480  -0.557   -78.255 1.00 70.48  ? 414  GLU E C     1 
ATOM   16359 O O     . GLU E 1 414 ? -62.409  0.236    -77.943 1.00 61.56  ? 414  GLU E O     1 
ATOM   16360 C CB    . GLU E 1 414 ? -62.641  -2.658   -79.017 1.00 62.81  ? 414  GLU E CB    1 
ATOM   16361 C CG    . GLU E 1 414 ? -62.650  -4.181   -78.975 1.00 66.79  ? 414  GLU E CG    1 
ATOM   16362 C CD    . GLU E 1 414 ? -63.493  -4.824   -80.043 1.00 76.56  ? 414  GLU E CD    1 
ATOM   16363 O OE1   . GLU E 1 414 ? -63.286  -6.036   -80.206 1.00 84.74  ? 414  GLU E OE1   1 
ATOM   16364 O OE2   . GLU E 1 414 ? -64.332  -4.158   -80.684 1.00 79.08  ? 414  GLU E OE2   1 
ATOM   16365 O OXT   . GLU E 1 414 ? -60.389  -0.221   -78.743 1.00 65.21  ? 414  GLU E OXT   1 
ATOM   16366 N N     . THR F 1 2   ? -79.802  -45.904  -23.450 1.00 79.04  ? 2    THR F N     1 
ATOM   16367 C CA    . THR F 1 2   ? -78.730  -46.466  -22.592 1.00 87.55  ? 2    THR F CA    1 
ATOM   16368 C C     . THR F 1 2   ? -77.915  -45.309  -22.033 1.00 83.02  ? 2    THR F C     1 
ATOM   16369 O O     . THR F 1 2   ? -77.977  -44.181  -22.531 1.00 71.13  ? 2    THR F O     1 
ATOM   16370 C CB    . THR F 1 2   ? -77.791  -47.430  -23.332 1.00 84.48  ? 2    THR F CB    1 
ATOM   16371 O OG1   . THR F 1 2   ? -78.499  -48.225  -24.270 1.00 91.65  ? 2    THR F OG1   1 
ATOM   16372 C CG2   . THR F 1 2   ? -77.021  -48.351  -22.394 1.00 78.97  ? 2    THR F CG2   1 
ATOM   16373 N N     . GLU F 1 3   ? -77.083  -45.639  -21.036 1.00 82.63  ? 3    GLU F N     1 
ATOM   16374 C CA    . GLU F 1 3   ? -76.144  -44.706  -20.447 1.00 85.02  ? 3    GLU F CA    1 
ATOM   16375 C C     . GLU F 1 3   ? -74.812  -44.771  -21.200 1.00 70.50  ? 3    GLU F C     1 
ATOM   16376 O O     . GLU F 1 3   ? -74.371  -45.849  -21.593 1.00 68.49  ? 3    GLU F O     1 
ATOM   16377 C CB    . GLU F 1 3   ? -76.206  -45.080  -18.968 1.00 89.24  ? 3    GLU F CB    1 
ATOM   16378 C CG    . GLU F 1 3   ? -75.091  -44.513  -18.096 1.00 102.04 ? 3    GLU F CG    1 
ATOM   16379 C CD    . GLU F 1 3   ? -75.381  -44.909  -16.660 1.00 115.58 ? 3    GLU F CD    1 
ATOM   16380 O OE1   . GLU F 1 3   ? -76.419  -44.417  -16.161 1.00 121.85 ? 3    GLU F OE1   1 
ATOM   16381 O OE2   . GLU F 1 3   ? -74.619  -45.709  -16.061 1.00 100.50 ? 3    GLU F OE2   1 
ATOM   16382 N N     . PRO F 1 4   ? -74.179  -43.613  -21.504 1.00 59.62  ? 4    PRO F N     1 
ATOM   16383 C CA    . PRO F 1 4   ? -72.869  -43.610  -22.141 1.00 52.53  ? 4    PRO F CA    1 
ATOM   16384 C C     . PRO F 1 4   ? -71.820  -44.396  -21.360 1.00 45.13  ? 4    PRO F C     1 
ATOM   16385 O O     . PRO F 1 4   ? -71.762  -44.278  -20.134 1.00 47.78  ? 4    PRO F O     1 
ATOM   16386 C CB    . PRO F 1 4   ? -72.487  -42.123  -22.208 1.00 56.30  ? 4    PRO F CB    1 
ATOM   16387 C CG    . PRO F 1 4   ? -73.514  -41.403  -21.341 1.00 55.98  ? 4    PRO F CG    1 
ATOM   16388 C CD    . PRO F 1 4   ? -74.728  -42.262  -21.302 1.00 51.95  ? 4    PRO F CD    1 
ATOM   16389 N N     . LEU F 1 5   ? -70.986  -45.161  -22.080 1.00 37.18  ? 5    LEU F N     1 
ATOM   16390 C CA    . LEU F 1 5   ? -69.782  -45.741  -21.506 1.00 35.48  ? 5    LEU F CA    1 
ATOM   16391 C C     . LEU F 1 5   ? -68.970  -44.669  -20.792 1.00 40.43  ? 5    LEU F C     1 
ATOM   16392 O O     . LEU F 1 5   ? -68.963  -43.497  -21.201 1.00 48.66  ? 5    LEU F O     1 
ATOM   16393 C CB    . LEU F 1 5   ? -68.949  -46.401  -22.604 1.00 34.41  ? 5    LEU F CB    1 
ATOM   16394 C CG    . LEU F 1 5   ? -69.571  -47.639  -23.263 1.00 41.65  ? 5    LEU F CG    1 
ATOM   16395 C CD1   . LEU F 1 5   ? -68.700  -48.128  -24.398 1.00 38.39  ? 5    LEU F CD1   1 
ATOM   16396 C CD2   . LEU F 1 5   ? -69.760  -48.755  -22.220 1.00 46.62  ? 5    LEU F CD2   1 
ATOM   16397 N N     . PRO F 1 6   ? -68.237  -45.013  -19.697 1.00 43.25  ? 6    PRO F N     1 
ATOM   16398 C CA    . PRO F 1 6   ? -67.379  -44.028  -19.033 1.00 33.99  ? 6    PRO F CA    1 
ATOM   16399 C C     . PRO F 1 6   ? -66.511  -43.185  -19.982 1.00 38.04  ? 6    PRO F C     1 
ATOM   16400 O O     . PRO F 1 6   ? -66.344  -41.987  -19.760 1.00 39.78  ? 6    PRO F O     1 
ATOM   16401 C CB    . PRO F 1 6   ? -66.609  -44.854  -17.978 1.00 31.23  ? 6    PRO F CB    1 
ATOM   16402 C CG    . PRO F 1 6   ? -67.597  -45.994  -17.700 1.00 33.96  ? 6    PRO F CG    1 
ATOM   16403 C CD    . PRO F 1 6   ? -68.290  -46.315  -19.004 1.00 35.08  ? 6    PRO F CD    1 
ATOM   16404 N N     . ARG F 1 7   ? -65.907  -43.802  -21.011 1.00 35.82  ? 7    ARG F N     1 
ATOM   16405 C CA    . ARG F 1 7   ? -64.930  -43.071  -21.802 1.00 33.94  ? 7    ARG F CA    1 
ATOM   16406 C C     . ARG F 1 7   ? -65.659  -42.020  -22.642 1.00 33.83  ? 7    ARG F C     1 
ATOM   16407 O O     . ARG F 1 7   ? -65.088  -40.976  -22.946 1.00 28.89  ? 7    ARG F O     1 
ATOM   16408 C CB    . ARG F 1 7   ? -64.025  -43.959  -22.681 1.00 28.18  ? 7    ARG F CB    1 
ATOM   16409 C CG    . ARG F 1 7   ? -64.722  -44.709  -23.812 1.00 24.08  ? 7    ARG F CG    1 
ATOM   16410 C CD    . ARG F 1 7   ? -63.776  -45.362  -24.822 1.00 24.55  ? 7    ARG F CD    1 
ATOM   16411 N NE    . ARG F 1 7   ? -64.566  -46.069  -25.850 1.00 35.10  ? 7    ARG F NE    1 
ATOM   16412 C CZ    . ARG F 1 7   ? -65.176  -47.257  -25.634 1.00 37.86  ? 7    ARG F CZ    1 
ATOM   16413 N NH1   . ARG F 1 7   ? -64.931  -47.907  -24.496 1.00 31.82  ? 7    ARG F NH1   1 
ATOM   16414 N NH2   . ARG F 1 7   ? -66.007  -47.776  -26.528 1.00 29.79  ? 7    ARG F NH2   1 
ATOM   16415 N N     . ILE F 1 8   ? -66.929  -42.293  -22.981 1.00 32.63  ? 8    ILE F N     1 
ATOM   16416 C CA    . ILE F 1 8   ? -67.752  -41.378  -23.760 1.00 33.62  ? 8    ILE F CA    1 
ATOM   16417 C C     . ILE F 1 8   ? -68.269  -40.220  -22.894 1.00 37.40  ? 8    ILE F C     1 
ATOM   16418 O O     . ILE F 1 8   ? -68.277  -39.070  -23.345 1.00 43.50  ? 8    ILE F O     1 
ATOM   16419 C CB    . ILE F 1 8   ? -68.838  -42.151  -24.525 1.00 30.55  ? 8    ILE F CB    1 
ATOM   16420 C CG1   . ILE F 1 8   ? -68.196  -43.121  -25.541 1.00 25.63  ? 8    ILE F CG1   1 
ATOM   16421 C CG2   . ILE F 1 8   ? -69.854  -41.213  -25.164 1.00 30.95  ? 8    ILE F CG2   1 
ATOM   16422 C CD1   . ILE F 1 8   ? -69.195  -43.946  -26.349 1.00 24.07  ? 8    ILE F CD1   1 
ATOM   16423 N N     . GLN F 1 9   ? -68.643  -40.505  -21.641 1.00 40.47  ? 9    GLN F N     1 
ATOM   16424 C CA    . GLN F 1 9   ? -68.943  -39.477  -20.653 1.00 39.71  ? 9    GLN F CA    1 
ATOM   16425 C C     . GLN F 1 9   ? -67.749  -38.542  -20.518 1.00 36.28  ? 9    GLN F C     1 
ATOM   16426 O O     . GLN F 1 9   ? -67.908  -37.325  -20.465 1.00 39.19  ? 9    GLN F O     1 
ATOM   16427 C CB    . GLN F 1 9   ? -69.232  -40.023  -19.254 1.00 46.11  ? 9    GLN F CB    1 
ATOM   16428 C CG    . GLN F 1 9   ? -70.717  -40.202  -18.938 1.00 72.46  ? 9    GLN F CG    1 
ATOM   16429 C CD    . GLN F 1 9   ? -70.975  -41.185  -17.810 1.00 93.10  ? 9    GLN F CD    1 
ATOM   16430 O OE1   . GLN F 1 9   ? -71.651  -42.216  -17.957 1.00 93.47  ? 9    GLN F OE1   1 
ATOM   16431 N NE2   . GLN F 1 9   ? -70.418  -40.865  -16.652 1.00 87.83  ? 9    GLN F NE2   1 
ATOM   16432 N N     . HIS F 1 10  ? -66.542  -39.113  -20.439 1.00 32.61  ? 10   HIS F N     1 
ATOM   16433 C CA    . HIS F 1 10  ? -65.342  -38.303  -20.282 1.00 33.90  ? 10   HIS F CA    1 
ATOM   16434 C C     . HIS F 1 10  ? -65.155  -37.430  -21.530 1.00 30.10  ? 10   HIS F C     1 
ATOM   16435 O O     . HIS F 1 10  ? -64.762  -36.270  -21.419 1.00 30.45  ? 10   HIS F O     1 
ATOM   16436 C CB    . HIS F 1 10  ? -64.139  -39.151  -19.842 1.00 37.50  ? 10   HIS F CB    1 
ATOM   16437 C CG    . HIS F 1 10  ? -62.880  -38.353  -19.634 1.00 58.45  ? 10   HIS F CG    1 
ATOM   16438 N ND1   . HIS F 1 10  ? -62.820  -37.291  -18.750 1.00 72.22  ? 10   HIS F ND1   1 
ATOM   16439 C CD2   . HIS F 1 10  ? -61.656  -38.403  -20.212 1.00 57.80  ? 10   HIS F CD2   1 
ATOM   16440 C CE1   . HIS F 1 10  ? -61.605  -36.744  -18.772 1.00 68.71  ? 10   HIS F CE1   1 
ATOM   16441 N NE2   . HIS F 1 10  ? -60.880  -37.401  -19.652 1.00 58.04  ? 10   HIS F NE2   1 
ATOM   16442 N N     . TYR F 1 11  ? -65.480  -37.991  -22.704 1.00 27.81  ? 11   TYR F N     1 
ATOM   16443 C CA    . TYR F 1 11  ? -65.346  -37.302  -23.976 1.00 29.35  ? 11   TYR F CA    1 
ATOM   16444 C C     . TYR F 1 11  ? -66.253  -36.062  -23.995 1.00 30.97  ? 11   TYR F C     1 
ATOM   16445 O O     . TYR F 1 11  ? -65.812  -34.976  -24.355 1.00 26.76  ? 11   TYR F O     1 
ATOM   16446 C CB    . TYR F 1 11  ? -65.625  -38.258  -25.137 1.00 24.39  ? 11   TYR F CB    1 
ATOM   16447 C CG    . TYR F 1 11  ? -65.717  -37.502  -26.453 1.00 30.77  ? 11   TYR F CG    1 
ATOM   16448 C CD1   . TYR F 1 11  ? -64.574  -37.158  -27.175 1.00 31.10  ? 11   TYR F CD1   1 
ATOM   16449 C CD2   . TYR F 1 11  ? -66.960  -37.102  -26.958 1.00 31.64  ? 11   TYR F CD2   1 
ATOM   16450 C CE1   . TYR F 1 11  ? -64.666  -36.438  -28.355 1.00 30.28  ? 11   TYR F CE1   1 
ATOM   16451 C CE2   . TYR F 1 11  ? -67.060  -36.368  -28.128 1.00 28.58  ? 11   TYR F CE2   1 
ATOM   16452 C CZ    . TYR F 1 11  ? -65.909  -36.043  -28.827 1.00 31.87  ? 11   TYR F CZ    1 
ATOM   16453 O OH    . TYR F 1 11  ? -66.037  -35.335  -29.988 1.00 29.28  ? 11   TYR F OH    1 
ATOM   16454 N N     . GLU F 1 12  ? -67.514  -36.227  -23.583 1.00 32.01  ? 12   GLU F N     1 
ATOM   16455 C CA    . GLU F 1 12  ? -68.467  -35.125  -23.593 1.00 29.64  ? 12   GLU F CA    1 
ATOM   16456 C C     . GLU F 1 12  ? -68.044  -34.011  -22.630 1.00 27.19  ? 12   GLU F C     1 
ATOM   16457 O O     . GLU F 1 12  ? -68.415  -32.849  -22.834 1.00 24.02  ? 12   GLU F O     1 
ATOM   16458 C CB    . GLU F 1 12  ? -69.902  -35.577  -23.344 1.00 27.00  ? 12   GLU F CB    1 
ATOM   16459 C CG    . GLU F 1 12  ? -70.378  -36.595  -24.369 1.00 27.09  ? 12   GLU F CG    1 
ATOM   16460 C CD    . GLU F 1 12  ? -71.848  -36.970  -24.230 1.00 33.45  ? 12   GLU F CD    1 
ATOM   16461 O OE1   . GLU F 1 12  ? -72.293  -37.217  -23.085 1.00 45.23  ? 12   GLU F OE1   1 
ATOM   16462 O OE2   . GLU F 1 12  ? -72.568  -37.008  -25.256 1.00 32.38  ? 12   GLU F OE2   1 
ATOM   16463 N N     . ASP F 1 13  ? -67.255  -34.359  -21.605 1.00 24.01  ? 13   ASP F N     1 
ATOM   16464 C CA    . ASP F 1 13  ? -66.778  -33.362  -20.667 1.00 24.41  ? 13   ASP F CA    1 
ATOM   16465 C C     . ASP F 1 13  ? -65.620  -32.566  -21.247 1.00 27.63  ? 13   ASP F C     1 
ATOM   16466 O O     . ASP F 1 13  ? -65.225  -31.546  -20.667 1.00 30.58  ? 13   ASP F O     1 
ATOM   16467 C CB    . ASP F 1 13  ? -66.304  -33.967  -19.358 1.00 30.25  ? 13   ASP F CB    1 
ATOM   16468 C CG    . ASP F 1 13  ? -67.394  -34.336  -18.350 1.00 39.85  ? 13   ASP F CG    1 
ATOM   16469 O OD1   . ASP F 1 13  ? -68.573  -33.925  -18.543 1.00 39.38  ? 13   ASP F OD1   1 
ATOM   16470 O OD2   . ASP F 1 13  ? -67.069  -35.047  -17.370 1.00 42.01  ? 13   ASP F OD2   1 
ATOM   16471 N N     . LEU F 1 14  ? -65.023  -33.054  -22.345 1.00 26.80  ? 14   LEU F N     1 
ATOM   16472 C CA    . LEU F 1 14  ? -63.894  -32.340  -22.928 1.00 28.43  ? 14   LEU F CA    1 
ATOM   16473 C C     . LEU F 1 14  ? -64.380  -31.009  -23.508 1.00 26.76  ? 14   LEU F C     1 
ATOM   16474 O O     . LEU F 1 14  ? -63.696  -30.007  -23.391 1.00 26.72  ? 14   LEU F O     1 
ATOM   16475 C CB    . LEU F 1 14  ? -63.222  -33.211  -23.989 1.00 28.01  ? 14   LEU F CB    1 
ATOM   16476 C CG    . LEU F 1 14  ? -62.647  -34.550  -23.516 1.00 29.60  ? 14   LEU F CG    1 
ATOM   16477 C CD1   . LEU F 1 14  ? -62.188  -35.282  -24.772 1.00 28.02  ? 14   LEU F CD1   1 
ATOM   16478 C CD2   . LEU F 1 14  ? -61.505  -34.377  -22.531 1.00 25.72  ? 14   LEU F CD2   1 
ATOM   16479 N N     . GLY F 1 15  ? -65.557  -31.025  -24.151 1.00 30.37  ? 15   GLY F N     1 
ATOM   16480 C CA    . GLY F 1 15  ? -66.220  -29.818  -24.626 1.00 27.66  ? 15   GLY F CA    1 
ATOM   16481 C C     . GLY F 1 15  ? -65.600  -29.247  -25.904 1.00 27.66  ? 15   GLY F C     1 
ATOM   16482 O O     . GLY F 1 15  ? -66.227  -29.250  -26.969 1.00 24.44  ? 15   GLY F O     1 
ATOM   16483 N N     . LEU F 1 16  ? -64.351  -28.791  -25.775 1.00 26.14  ? 16   LEU F N     1 
ATOM   16484 C CA    . LEU F 1 16  ? -63.666  -28.087  -26.840 1.00 27.04  ? 16   LEU F CA    1 
ATOM   16485 C C     . LEU F 1 16  ? -62.333  -28.772  -27.142 1.00 26.53  ? 16   LEU F C     1 
ATOM   16486 O O     . LEU F 1 16  ? -61.541  -29.061  -26.234 1.00 26.31  ? 16   LEU F O     1 
ATOM   16487 C CB    . LEU F 1 16  ? -63.464  -26.636  -26.372 1.00 24.59  ? 16   LEU F CB    1 
ATOM   16488 C CG    . LEU F 1 16  ? -62.507  -25.790  -27.221 1.00 25.17  ? 16   LEU F CG    1 
ATOM   16489 C CD1   . LEU F 1 16  ? -63.026  -25.525  -28.623 1.00 20.43  ? 16   LEU F CD1   1 
ATOM   16490 C CD2   . LEU F 1 16  ? -62.167  -24.477  -26.543 1.00 26.61  ? 16   LEU F CD2   1 
ATOM   16491 N N     . GLY F 1 17  ? -62.083  -28.998  -28.432 1.00 24.54  ? 17   GLY F N     1 
ATOM   16492 C CA    . GLY F 1 17  ? -60.764  -29.452  -28.857 1.00 22.99  ? 17   GLY F CA    1 
ATOM   16493 C C     . GLY F 1 17  ? -60.181  -28.549  -29.939 1.00 23.05  ? 17   GLY F C     1 
ATOM   16494 O O     . GLY F 1 17  ? -60.913  -27.835  -30.638 1.00 26.66  ? 17   GLY F O     1 
ATOM   16495 N N     . LEU F 1 18  ? -58.864  -28.613  -30.095 1.00 22.38  ? 18   LEU F N     1 
ATOM   16496 C CA    . LEU F 1 18  ? -58.188  -27.953  -31.188 1.00 24.82  ? 18   LEU F CA    1 
ATOM   16497 C C     . LEU F 1 18  ? -57.875  -28.987  -32.277 1.00 24.97  ? 18   LEU F C     1 
ATOM   16498 O O     . LEU F 1 18  ? -57.292  -30.040  -31.989 1.00 24.07  ? 18   LEU F O     1 
ATOM   16499 C CB    . LEU F 1 18  ? -56.941  -27.400  -30.519 1.00 24.60  ? 18   LEU F CB    1 
ATOM   16500 C CG    . LEU F 1 18  ? -56.140  -26.432  -31.389 1.00 33.09  ? 18   LEU F CG    1 
ATOM   16501 C CD1   . LEU F 1 18  ? -57.017  -25.212  -31.568 1.00 34.39  ? 18   LEU F CD1   1 
ATOM   16502 C CD2   . LEU F 1 18  ? -54.806  -26.084  -30.717 1.00 35.47  ? 18   LEU F CD2   1 
ATOM   16503 N N     . PHE F 1 19  ? -58.281  -28.682  -33.517 1.00 21.82  ? 19   PHE F N     1 
ATOM   16504 C CA    . PHE F 1 19  ? -57.951  -29.487  -34.679 1.00 23.69  ? 19   PHE F CA    1 
ATOM   16505 C C     . PHE F 1 19  ? -56.725  -28.865  -35.352 1.00 25.75  ? 19   PHE F C     1 
ATOM   16506 O O     . PHE F 1 19  ? -56.700  -27.644  -35.543 1.00 27.54  ? 19   PHE F O     1 
ATOM   16507 C CB    . PHE F 1 19  ? -59.144  -29.399  -35.640 1.00 22.45  ? 19   PHE F CB    1 
ATOM   16508 C CG    . PHE F 1 19  ? -59.427  -30.610  -36.520 1.00 25.33  ? 19   PHE F CG    1 
ATOM   16509 C CD1   . PHE F 1 19  ? -58.420  -31.531  -36.843 1.00 26.30  ? 19   PHE F CD1   1 
ATOM   16510 C CD2   . PHE F 1 19  ? -60.707  -30.824  -37.040 1.00 23.75  ? 19   PHE F CD2   1 
ATOM   16511 C CE1   . PHE F 1 19  ? -58.694  -32.641  -37.646 1.00 26.04  ? 19   PHE F CE1   1 
ATOM   16512 C CE2   . PHE F 1 19  ? -60.982  -31.940  -37.838 1.00 26.89  ? 19   PHE F CE2   1 
ATOM   16513 C CZ    . PHE F 1 19  ? -59.979  -32.850  -38.138 1.00 25.71  ? 19   PHE F CZ    1 
ATOM   16514 N N     . ILE F 1 20  ? -55.722  -29.688  -35.711 1.00 22.68  ? 20   ILE F N     1 
ATOM   16515 C CA    . ILE F 1 20  ? -54.518  -29.169  -36.348 1.00 23.16  ? 20   ILE F CA    1 
ATOM   16516 C C     . ILE F 1 20  ? -54.224  -29.908  -37.657 1.00 23.31  ? 20   ILE F C     1 
ATOM   16517 O O     . ILE F 1 20  ? -54.020  -31.122  -37.644 1.00 23.20  ? 20   ILE F O     1 
ATOM   16518 C CB    . ILE F 1 20  ? -53.322  -29.241  -35.394 1.00 26.03  ? 20   ILE F CB    1 
ATOM   16519 C CG1   . ILE F 1 20  ? -53.583  -28.436  -34.136 1.00 25.27  ? 20   ILE F CG1   1 
ATOM   16520 C CG2   . ILE F 1 20  ? -52.039  -28.795  -36.120 1.00 24.97  ? 20   ILE F CG2   1 
ATOM   16521 C CD1   . ILE F 1 20  ? -52.415  -28.490  -33.154 1.00 27.65  ? 20   ILE F CD1   1 
ATOM   16522 N N     . HIS F 1 21  ? -54.207  -29.157  -38.768 1.00 21.25  ? 21   HIS F N     1 
ATOM   16523 C CA    . HIS F 1 21  ? -53.877  -29.666  -40.083 1.00 20.47  ? 21   HIS F CA    1 
ATOM   16524 C C     . HIS F 1 21  ? -52.462  -29.213  -40.423 1.00 23.40  ? 21   HIS F C     1 
ATOM   16525 O O     . HIS F 1 21  ? -52.159  -28.009  -40.526 1.00 21.31  ? 21   HIS F O     1 
ATOM   16526 C CB    . HIS F 1 21  ? -54.843  -29.123  -41.144 1.00 19.52  ? 21   HIS F CB    1 
ATOM   16527 C CG    . HIS F 1 21  ? -56.113  -29.898  -41.193 1.00 19.66  ? 21   HIS F CG    1 
ATOM   16528 N ND1   . HIS F 1 21  ? -57.062  -29.834  -40.189 1.00 17.57  ? 21   HIS F ND1   1 
ATOM   16529 C CD2   . HIS F 1 21  ? -56.568  -30.825  -42.118 1.00 19.27  ? 21   HIS F CD2   1 
ATOM   16530 C CE1   . HIS F 1 21  ? -58.071  -30.671  -40.487 1.00 18.83  ? 21   HIS F CE1   1 
ATOM   16531 N NE2   . HIS F 1 21  ? -57.787  -31.277  -41.669 1.00 17.99  ? 21   HIS F NE2   1 
ATOM   16532 N N     . TRP F 1 22  ? -51.592  -30.207  -40.605 1.00 23.13  ? 22   TRP F N     1 
ATOM   16533 C CA    . TRP F 1 22  ? -50.226  -29.946  -41.004 1.00 21.00  ? 22   TRP F CA    1 
ATOM   16534 C C     . TRP F 1 22  ? -49.723  -31.148  -41.794 1.00 21.74  ? 22   TRP F C     1 
ATOM   16535 O O     . TRP F 1 22  ? -49.830  -32.276  -41.316 1.00 20.98  ? 22   TRP F O     1 
ATOM   16536 C CB    . TRP F 1 22  ? -49.400  -29.767  -39.735 1.00 19.29  ? 22   TRP F CB    1 
ATOM   16537 C CG    . TRP F 1 22  ? -47.959  -29.430  -40.000 1.00 20.76  ? 22   TRP F CG    1 
ATOM   16538 C CD1   . TRP F 1 22  ? -47.441  -28.642  -40.995 1.00 19.13  ? 22   TRP F CD1   1 
ATOM   16539 C CD2   . TRP F 1 22  ? -46.840  -29.890  -39.207 1.00 20.41  ? 22   TRP F CD2   1 
ATOM   16540 N NE1   . TRP F 1 22  ? -46.076  -28.559  -40.865 1.00 19.49  ? 22   TRP F NE1   1 
ATOM   16541 C CE2   . TRP F 1 22  ? -45.679  -29.324  -39.788 1.00 19.15  ? 22   TRP F CE2   1 
ATOM   16542 C CE3   . TRP F 1 22  ? -46.722  -30.714  -38.079 1.00 21.34  ? 22   TRP F CE3   1 
ATOM   16543 C CZ2   . TRP F 1 22  ? -44.415  -29.565  -39.265 1.00 18.84  ? 22   TRP F CZ2   1 
ATOM   16544 C CZ3   . TRP F 1 22  ? -45.468  -30.934  -37.546 1.00 22.17  ? 22   TRP F CZ3   1 
ATOM   16545 C CH2   . TRP F 1 22  ? -44.335  -30.372  -38.144 1.00 21.60  ? 22   TRP F CH2   1 
ATOM   16546 N N     . GLY F 1 23  ? -49.181  -30.886  -42.985 1.00 21.50  ? 23   GLY F N     1 
ATOM   16547 C CA    . GLY F 1 23  ? -48.633  -31.932  -43.840 1.00 21.99  ? 23   GLY F CA    1 
ATOM   16548 C C     . GLY F 1 23  ? -47.749  -31.296  -44.913 1.00 22.66  ? 23   GLY F C     1 
ATOM   16549 O O     . GLY F 1 23  ? -47.392  -30.131  -44.788 1.00 22.18  ? 23   GLY F O     1 
ATOM   16550 N N     . LEU F 1 24  ? -47.426  -32.040  -45.971 1.00 22.33  ? 24   LEU F N     1 
ATOM   16551 C CA    . LEU F 1 24  ? -46.567  -31.491  -47.014 1.00 22.34  ? 24   LEU F CA    1 
ATOM   16552 C C     . LEU F 1 24  ? -47.294  -30.325  -47.680 1.00 23.21  ? 24   LEU F C     1 
ATOM   16553 O O     . LEU F 1 24  ? -46.652  -29.346  -48.057 1.00 23.46  ? 24   LEU F O     1 
ATOM   16554 C CB    . LEU F 1 24  ? -46.135  -32.543  -48.035 1.00 21.91  ? 24   LEU F CB    1 
ATOM   16555 C CG    . LEU F 1 24  ? -45.381  -33.750  -47.463 1.00 24.84  ? 24   LEU F CG    1 
ATOM   16556 C CD1   . LEU F 1 24  ? -45.061  -34.779  -48.545 1.00 20.47  ? 24   LEU F CD1   1 
ATOM   16557 C CD2   . LEU F 1 24  ? -44.126  -33.355  -46.642 1.00 23.14  ? 24   LEU F CD2   1 
ATOM   16558 N N     . TYR F 1 25  ? -48.634  -30.427  -47.796 1.00 22.71  ? 25   TYR F N     1 
ATOM   16559 C CA    . TYR F 1 25  ? -49.457  -29.399  -48.426 1.00 21.42  ? 25   TYR F CA    1 
ATOM   16560 C C     . TYR F 1 25  ? -49.185  -28.035  -47.795 1.00 20.86  ? 25   TYR F C     1 
ATOM   16561 O O     . TYR F 1 25  ? -49.292  -27.024  -48.491 1.00 19.60  ? 25   TYR F O     1 
ATOM   16562 C CB    . TYR F 1 25  ? -50.961  -29.682  -48.314 1.00 19.59  ? 25   TYR F CB    1 
ATOM   16563 C CG    . TYR F 1 25  ? -51.403  -30.178  -46.947 1.00 18.94  ? 25   TYR F CG    1 
ATOM   16564 C CD1   . TYR F 1 25  ? -51.675  -29.305  -45.890 1.00 17.64  ? 25   TYR F CD1   1 
ATOM   16565 C CD2   . TYR F 1 25  ? -51.546  -31.542  -46.709 1.00 17.37  ? 25   TYR F CD2   1 
ATOM   16566 C CE1   . TYR F 1 25  ? -52.079  -29.782  -44.641 1.00 18.49  ? 25   TYR F CE1   1 
ATOM   16567 C CE2   . TYR F 1 25  ? -51.925  -32.030  -45.464 1.00 17.45  ? 25   TYR F CE2   1 
ATOM   16568 C CZ    . TYR F 1 25  ? -52.200  -31.149  -44.430 1.00 19.31  ? 25   TYR F CZ    1 
ATOM   16569 O OH    . TYR F 1 25  ? -52.567  -31.656  -43.203 1.00 19.98  ? 25   TYR F OH    1 
ATOM   16570 N N     . SER F 1 26  ? -48.836  -28.016  -46.498 1.00 20.96  ? 26   SER F N     1 
ATOM   16571 C CA    . SER F 1 26  ? -48.668  -26.752  -45.777 1.00 22.38  ? 26   SER F CA    1 
ATOM   16572 C C     . SER F 1 26  ? -47.607  -25.873  -46.436 1.00 23.55  ? 26   SER F C     1 
ATOM   16573 O O     . SER F 1 26  ? -47.674  -24.645  -46.383 1.00 25.85  ? 26   SER F O     1 
ATOM   16574 C CB    . SER F 1 26  ? -48.346  -26.984  -44.308 1.00 19.68  ? 26   SER F CB    1 
ATOM   16575 O OG    . SER F 1 26  ? -49.329  -27.828  -43.715 1.00 20.72  ? 26   SER F OG    1 
ATOM   16576 N N     . GLN F 1 27  ? -46.614  -26.506  -47.071 1.00 24.93  ? 27   GLN F N     1 
ATOM   16577 C CA    . GLN F 1 27  ? -45.562  -25.724  -47.700 1.00 22.98  ? 27   GLN F CA    1 
ATOM   16578 C C     . GLN F 1 27  ? -46.085  -24.894  -48.870 1.00 24.56  ? 27   GLN F C     1 
ATOM   16579 O O     . GLN F 1 27  ? -45.483  -23.896  -49.189 1.00 30.21  ? 27   GLN F O     1 
ATOM   16580 C CB    . GLN F 1 27  ? -44.375  -26.546  -48.165 1.00 23.75  ? 27   GLN F CB    1 
ATOM   16581 C CG    . GLN F 1 27  ? -43.509  -27.044  -47.015 1.00 25.29  ? 27   GLN F CG    1 
ATOM   16582 C CD    . GLN F 1 27  ? -42.579  -28.147  -47.489 1.00 30.06  ? 27   GLN F CD    1 
ATOM   16583 O OE1   . GLN F 1 27  ? -42.740  -29.335  -47.145 1.00 30.43  ? 27   GLN F OE1   1 
ATOM   16584 N NE2   . GLN F 1 27  ? -41.613  -27.758  -48.312 1.00 25.96  ? 27   GLN F NE2   1 
ATOM   16585 N N     . MET F 1 28  ? -47.211  -25.242  -49.480 1.00 23.42  ? 28   MET F N     1 
ATOM   16586 C CA    . MET F 1 28  ? -47.681  -24.480  -50.628 1.00 24.84  ? 28   MET F CA    1 
ATOM   16587 C C     . MET F 1 28  ? -48.746  -23.456  -50.232 1.00 26.87  ? 28   MET F C     1 
ATOM   16588 O O     . MET F 1 28  ? -49.025  -22.559  -51.008 1.00 27.58  ? 28   MET F O     1 
ATOM   16589 C CB    . MET F 1 28  ? -48.415  -25.411  -51.585 1.00 28.36  ? 28   MET F CB    1 
ATOM   16590 C CG    . MET F 1 28  ? -47.734  -26.728  -51.772 1.00 41.21  ? 28   MET F CG    1 
ATOM   16591 S SD    . MET F 1 28  ? -46.884  -26.647  -53.344 1.00 69.87  ? 28   MET F SD    1 
ATOM   16592 C CE    . MET F 1 28  ? -45.525  -25.503  -53.005 1.00 41.06  ? 28   MET F CE    1 
ATOM   16593 N N     . ALA F 1 29  ? -49.419  -23.652  -49.085 1.00 25.61  ? 29   ALA F N     1 
ATOM   16594 C CA    . ALA F 1 29  ? -50.344  -22.664  -48.534 1.00 25.48  ? 29   ALA F CA    1 
ATOM   16595 C C     . ALA F 1 29  ? -51.491  -22.378  -49.506 1.00 26.75  ? 29   ALA F C     1 
ATOM   16596 O O     . ALA F 1 29  ? -51.948  -21.227  -49.632 1.00 22.90  ? 29   ALA F O     1 
ATOM   16597 C CB    . ALA F 1 29  ? -49.603  -21.392  -48.126 1.00 22.49  ? 29   ALA F CB    1 
ATOM   16598 N N     . VAL F 1 30  ? -51.960  -23.438  -50.190 1.00 21.94  ? 30   VAL F N     1 
ATOM   16599 C CA    . VAL F 1 30  ? -53.131  -23.305  -51.037 1.00 20.06  ? 30   VAL F CA    1 
ATOM   16600 C C     . VAL F 1 30  ? -54.107  -24.449  -50.715 1.00 23.23  ? 30   VAL F C     1 
ATOM   16601 O O     . VAL F 1 30  ? -54.762  -24.969  -51.619 1.00 21.20  ? 30   VAL F O     1 
ATOM   16602 C CB    . VAL F 1 30  ? -52.775  -23.233  -52.544 1.00 21.14  ? 30   VAL F CB    1 
ATOM   16603 C CG1   . VAL F 1 30  ? -52.100  -21.932  -52.964 1.00 17.06  ? 30   VAL F CG1   1 
ATOM   16604 C CG2   . VAL F 1 30  ? -51.898  -24.407  -53.010 1.00 20.69  ? 30   VAL F CG2   1 
ATOM   16605 N N     . GLY F 1 31  ? -54.239  -24.837  -49.431 1.00 20.85  ? 31   GLY F N     1 
ATOM   16606 C CA    . GLY F 1 31  ? -55.250  -25.819  -49.043 1.00 20.93  ? 31   GLY F CA    1 
ATOM   16607 C C     . GLY F 1 31  ? -54.693  -27.257  -49.006 1.00 24.75  ? 31   GLY F C     1 
ATOM   16608 O O     . GLY F 1 31  ? -53.743  -27.595  -49.736 1.00 23.16  ? 31   GLY F O     1 
ATOM   16609 N N     . GLU F 1 32  ? -55.296  -28.104  -48.151 1.00 20.22  ? 32   GLU F N     1 
ATOM   16610 C CA    . GLU F 1 32  ? -54.764  -29.442  -47.923 1.00 21.37  ? 32   GLU F CA    1 
ATOM   16611 C C     . GLU F 1 32  ? -55.070  -30.391  -49.096 1.00 23.91  ? 32   GLU F C     1 
ATOM   16612 O O     . GLU F 1 32  ? -54.412  -31.414  -49.239 1.00 26.21  ? 32   GLU F O     1 
ATOM   16613 C CB    . GLU F 1 32  ? -55.194  -30.020  -46.571 1.00 18.31  ? 32   GLU F CB    1 
ATOM   16614 C CG    . GLU F 1 32  ? -56.684  -30.331  -46.480 1.00 21.33  ? 32   GLU F CG    1 
ATOM   16615 C CD    . GLU F 1 32  ? -57.697  -29.182  -46.431 1.00 27.70  ? 32   GLU F CD    1 
ATOM   16616 O OE1   . GLU F 1 32  ? -58.913  -29.503  -46.527 1.00 25.61  ? 32   GLU F OE1   1 
ATOM   16617 O OE2   . GLU F 1 32  ? -57.290  -27.993  -46.296 1.00 24.83  ? 32   GLU F OE2   1 
ATOM   16618 N N     . TRP F 1 33  ? -56.077  -30.086  -49.918 1.00 22.83  ? 33   TRP F N     1 
ATOM   16619 C CA    . TRP F 1 33  ? -56.414  -30.914  -51.069 1.00 24.35  ? 33   TRP F CA    1 
ATOM   16620 C C     . TRP F 1 33  ? -55.632  -30.533  -52.331 1.00 25.30  ? 33   TRP F C     1 
ATOM   16621 O O     . TRP F 1 33  ? -55.988  -30.972  -53.414 1.00 22.99  ? 33   TRP F O     1 
ATOM   16622 C CB    . TRP F 1 33  ? -57.916  -30.836  -51.368 1.00 21.76  ? 33   TRP F CB    1 
ATOM   16623 C CG    . TRP F 1 33  ? -58.777  -31.731  -50.514 1.00 22.02  ? 33   TRP F CG    1 
ATOM   16624 C CD1   . TRP F 1 33  ? -59.011  -31.612  -49.173 1.00 22.40  ? 33   TRP F CD1   1 
ATOM   16625 C CD2   . TRP F 1 33  ? -59.582  -32.845  -50.973 1.00 20.92  ? 33   TRP F CD2   1 
ATOM   16626 N NE1   . TRP F 1 33  ? -59.864  -32.605  -48.758 1.00 23.54  ? 33   TRP F NE1   1 
ATOM   16627 C CE2   . TRP F 1 33  ? -60.242  -33.365  -49.837 1.00 22.09  ? 33   TRP F CE2   1 
ATOM   16628 C CE3   . TRP F 1 33  ? -59.815  -33.445  -52.222 1.00 23.83  ? 33   TRP F CE3   1 
ATOM   16629 C CZ2   . TRP F 1 33  ? -61.111  -34.456  -49.916 1.00 25.28  ? 33   TRP F CZ2   1 
ATOM   16630 C CZ3   . TRP F 1 33  ? -60.695  -34.513  -52.298 1.00 26.85  ? 33   TRP F CZ3   1 
ATOM   16631 C CH2   . TRP F 1 33  ? -61.339  -35.016  -51.157 1.00 24.59  ? 33   TRP F CH2   1 
ATOM   16632 N N     . THR F 1 34  ? -54.583  -29.710  -52.211 1.00 25.19  ? 34   THR F N     1 
ATOM   16633 C CA    . THR F 1 34  ? -53.958  -29.122  -53.390 1.00 24.42  ? 34   THR F CA    1 
ATOM   16634 C C     . THR F 1 34  ? -53.507  -30.187  -54.407 1.00 27.06  ? 34   THR F C     1 
ATOM   16635 O O     . THR F 1 34  ? -53.659  -29.999  -55.624 1.00 26.21  ? 34   THR F O     1 
ATOM   16636 C CB    . THR F 1 34  ? -52.824  -28.182  -52.978 1.00 26.13  ? 34   THR F CB    1 
ATOM   16637 O OG1   . THR F 1 34  ? -52.344  -27.652  -54.209 1.00 26.29  ? 34   THR F OG1   1 
ATOM   16638 C CG2   . THR F 1 34  ? -51.667  -28.873  -52.277 1.00 21.83  ? 34   THR F CG2   1 
ATOM   16639 N N     . GLU F 1 35  ? -52.956  -31.320  -53.931 1.00 26.40  ? 35   GLU F N     1 
ATOM   16640 C CA    . GLU F 1 35  ? -52.409  -32.308  -54.853 1.00 29.50  ? 35   GLU F CA    1 
ATOM   16641 C C     . GLU F 1 35  ? -53.474  -32.786  -55.850 1.00 28.29  ? 35   GLU F C     1 
ATOM   16642 O O     . GLU F 1 35  ? -53.208  -32.841  -57.052 1.00 25.43  ? 35   GLU F O     1 
ATOM   16643 C CB    . GLU F 1 35  ? -51.709  -33.477  -54.167 1.00 26.62  ? 35   GLU F CB    1 
ATOM   16644 C CG    . GLU F 1 35  ? -51.125  -34.463  -55.175 1.00 28.58  ? 35   GLU F CG    1 
ATOM   16645 C CD    . GLU F 1 35  ? -50.469  -35.674  -54.530 1.00 32.66  ? 35   GLU F CD    1 
ATOM   16646 O OE1   . GLU F 1 35  ? -50.771  -36.018  -53.359 1.00 31.00  ? 35   GLU F OE1   1 
ATOM   16647 O OE2   . GLU F 1 35  ? -49.593  -36.243  -55.201 1.00 35.81  ? 35   GLU F OE2   1 
ATOM   16648 N N     . LEU F 1 36  ? -54.666  -33.132  -55.337 1.00 26.96  ? 36   LEU F N     1 
ATOM   16649 C CA    . LEU F 1 36  ? -55.729  -33.602  -56.197 1.00 27.69  ? 36   LEU F CA    1 
ATOM   16650 C C     . LEU F 1 36  ? -56.371  -32.430  -56.948 1.00 31.67  ? 36   LEU F C     1 
ATOM   16651 O O     . LEU F 1 36  ? -56.471  -32.463  -58.179 1.00 30.44  ? 36   LEU F O     1 
ATOM   16652 C CB    . LEU F 1 36  ? -56.762  -34.413  -55.428 1.00 28.76  ? 36   LEU F CB    1 
ATOM   16653 C CG    . LEU F 1 36  ? -57.887  -35.022  -56.281 1.00 34.73  ? 36   LEU F CG    1 
ATOM   16654 C CD1   . LEU F 1 36  ? -57.324  -36.052  -57.233 1.00 40.24  ? 36   LEU F CD1   1 
ATOM   16655 C CD2   . LEU F 1 36  ? -58.852  -35.745  -55.401 1.00 37.33  ? 36   LEU F CD2   1 
ATOM   16656 N N     . ILE F 1 37  ? -56.792  -31.383  -56.224 1.00 25.42  ? 37   ILE F N     1 
ATOM   16657 C CA    . ILE F 1 37  ? -57.657  -30.392  -56.835 1.00 26.99  ? 37   ILE F CA    1 
ATOM   16658 C C     . ILE F 1 37  ? -56.898  -29.532  -57.853 1.00 30.55  ? 37   ILE F C     1 
ATOM   16659 O O     . ILE F 1 37  ? -57.481  -29.098  -58.837 1.00 30.12  ? 37   ILE F O     1 
ATOM   16660 C CB    . ILE F 1 37  ? -58.411  -29.564  -55.778 1.00 28.02  ? 37   ILE F CB    1 
ATOM   16661 C CG1   . ILE F 1 37  ? -59.416  -30.458  -55.058 1.00 27.29  ? 37   ILE F CG1   1 
ATOM   16662 C CG2   . ILE F 1 37  ? -59.102  -28.347  -56.412 1.00 24.85  ? 37   ILE F CG2   1 
ATOM   16663 C CD1   . ILE F 1 37  ? -60.107  -29.760  -53.895 1.00 30.68  ? 37   ILE F CD1   1 
ATOM   16664 N N     . HIS F 1 38  ? -55.606  -29.275  -57.632 1.00 26.57  ? 38   HIS F N     1 
ATOM   16665 C CA    . HIS F 1 38  ? -54.840  -28.504  -58.598 1.00 27.82  ? 38   HIS F CA    1 
ATOM   16666 C C     . HIS F 1 38  ? -54.152  -29.420  -59.608 1.00 29.75  ? 38   HIS F C     1 
ATOM   16667 O O     . HIS F 1 38  ? -53.251  -28.939  -60.303 1.00 29.57  ? 38   HIS F O     1 
ATOM   16668 C CB    . HIS F 1 38  ? -53.774  -27.648  -57.894 1.00 26.42  ? 38   HIS F CB    1 
ATOM   16669 C CG    . HIS F 1 38  ? -54.359  -26.523  -57.113 1.00 29.92  ? 38   HIS F CG    1 
ATOM   16670 N ND1   . HIS F 1 38  ? -54.069  -26.308  -55.774 1.00 29.66  ? 38   HIS F ND1   1 
ATOM   16671 C CD2   . HIS F 1 38  ? -55.264  -25.568  -57.495 1.00 29.25  ? 38   HIS F CD2   1 
ATOM   16672 C CE1   . HIS F 1 38  ? -54.750  -25.227  -55.368 1.00 29.85  ? 38   HIS F CE1   1 
ATOM   16673 N NE2   . HIS F 1 38  ? -55.487  -24.761  -56.390 1.00 29.34  ? 38   HIS F NE2   1 
ATOM   16674 N N     . HIS F 1 39  ? -54.511  -30.730  -59.632 1.00 33.05  ? 39   HIS F N     1 
ATOM   16675 C CA    . HIS F 1 39  ? -54.033  -31.673  -60.646 1.00 38.27  ? 39   HIS F CA    1 
ATOM   16676 C C     . HIS F 1 39  ? -52.495  -31.653  -60.711 1.00 35.66  ? 39   HIS F C     1 
ATOM   16677 O O     . HIS F 1 39  ? -51.898  -31.459  -61.767 1.00 38.60  ? 39   HIS F O     1 
ATOM   16678 C CB    . HIS F 1 39  ? -54.746  -31.455  -62.007 1.00 42.65  ? 39   HIS F CB    1 
ATOM   16679 C CG    . HIS F 1 39  ? -54.478  -32.536  -63.042 1.00 90.77  ? 39   HIS F CG    1 
ATOM   16680 N ND1   . HIS F 1 39  ? -54.958  -33.836  -62.957 1.00 91.98  ? 39   HIS F ND1   1 
ATOM   16681 C CD2   . HIS F 1 39  ? -53.741  -32.514  -64.188 1.00 94.81  ? 39   HIS F CD2   1 
ATOM   16682 C CE1   . HIS F 1 39  ? -54.554  -34.552  -64.002 1.00 68.80  ? 39   HIS F CE1   1 
ATOM   16683 N NE2   . HIS F 1 39  ? -53.811  -33.768  -64.762 1.00 82.52  ? 39   HIS F NE2   1 
ATOM   16684 N N     . ARG F 1 40  ? -51.823  -31.776  -59.570 1.00 33.39  ? 40   ARG F N     1 
ATOM   16685 C CA    . ARG F 1 40  ? -50.374  -31.644  -59.602 1.00 29.76  ? 40   ARG F CA    1 
ATOM   16686 C C     . ARG F 1 40  ? -49.735  -32.966  -60.032 1.00 32.15  ? 40   ARG F C     1 
ATOM   16687 O O     . ARG F 1 40  ? -50.311  -34.033  -59.838 1.00 31.85  ? 40   ARG F O     1 
ATOM   16688 C CB    . ARG F 1 40  ? -49.880  -31.287  -58.197 1.00 28.80  ? 40   ARG F CB    1 
ATOM   16689 C CG    . ARG F 1 40  ? -50.220  -29.847  -57.852 1.00 32.96  ? 40   ARG F CG    1 
ATOM   16690 C CD    . ARG F 1 40  ? -49.652  -29.581  -56.474 1.00 36.33  ? 40   ARG F CD    1 
ATOM   16691 N NE    . ARG F 1 40  ? -50.137  -28.304  -55.928 1.00 45.01  ? 40   ARG F NE    1 
ATOM   16692 C CZ    . ARG F 1 40  ? -49.648  -27.096  -56.184 1.00 50.23  ? 40   ARG F CZ    1 
ATOM   16693 N NH1   . ARG F 1 40  ? -48.574  -26.987  -56.956 1.00 47.40  ? 40   ARG F NH1   1 
ATOM   16694 N NH2   . ARG F 1 40  ? -50.176  -26.033  -55.616 1.00 42.83  ? 40   ARG F NH2   1 
ATOM   16695 N N     . ASN F 1 41  ? -48.536  -32.881  -60.614 1.00 33.62  ? 41   ASN F N     1 
ATOM   16696 C CA    . ASN F 1 41  ? -47.701  -34.043  -60.855 1.00 29.20  ? 41   ASN F CA    1 
ATOM   16697 C C     . ASN F 1 41  ? -47.335  -34.721  -59.520 1.00 29.38  ? 41   ASN F C     1 
ATOM   16698 O O     . ASN F 1 41  ? -46.656  -34.127  -58.672 1.00 28.61  ? 41   ASN F O     1 
ATOM   16699 C CB    . ASN F 1 41  ? -46.469  -33.635  -61.665 1.00 31.31  ? 41   ASN F CB    1 
ATOM   16700 C CG    . ASN F 1 41  ? -45.539  -34.808  -61.873 1.00 39.47  ? 41   ASN F CG    1 
ATOM   16701 O OD1   . ASN F 1 41  ? -44.679  -35.104  -61.033 1.00 46.16  ? 41   ASN F OD1   1 
ATOM   16702 N ND2   . ASN F 1 41  ? -45.763  -35.571  -62.923 1.00 39.90  ? 41   ASN F ND2   1 
ATOM   16703 N N     . GLN F 1 42  ? -47.712  -35.995  -59.358 1.00 26.65  ? 42   GLN F N     1 
ATOM   16704 C CA    . GLN F 1 42  ? -47.495  -36.683  -58.092 1.00 29.31  ? 42   GLN F CA    1 
ATOM   16705 C C     . GLN F 1 42  ? -46.019  -36.662  -57.668 1.00 33.14  ? 42   GLN F C     1 
ATOM   16706 O O     . GLN F 1 42  ? -45.672  -36.376  -56.512 1.00 31.33  ? 42   GLN F O     1 
ATOM   16707 C CB    . GLN F 1 42  ? -48.043  -38.104  -58.066 1.00 24.83  ? 42   GLN F CB    1 
ATOM   16708 C CG    . GLN F 1 42  ? -47.836  -38.770  -56.712 1.00 30.18  ? 42   GLN F CG    1 
ATOM   16709 C CD    . GLN F 1 42  ? -48.632  -40.055  -56.578 1.00 39.36  ? 42   GLN F CD    1 
ATOM   16710 O OE1   . GLN F 1 42  ? -48.681  -40.701  -55.523 1.00 48.90  ? 42   GLN F OE1   1 
ATOM   16711 N NE2   . GLN F 1 42  ? -49.273  -40.447  -57.671 1.00 40.58  ? 42   GLN F NE2   1 
ATOM   16712 N N     . HIS F 1 43  ? -45.140  -36.983  -58.620 1.00 31.84  ? 43   HIS F N     1 
ATOM   16713 C CA    . HIS F 1 43  ? -43.734  -37.102  -58.327 1.00 30.54  ? 43   HIS F CA    1 
ATOM   16714 C C     . HIS F 1 43  ? -43.217  -35.757  -57.803 1.00 28.68  ? 43   HIS F C     1 
ATOM   16715 O O     . HIS F 1 43  ? -42.430  -35.718  -56.861 1.00 29.61  ? 43   HIS F O     1 
ATOM   16716 C CB    . HIS F 1 43  ? -42.965  -37.669  -59.539 1.00 30.33  ? 43   HIS F CB    1 
ATOM   16717 C CG    . HIS F 1 43  ? -41.489  -37.612  -59.310 1.00 38.46  ? 43   HIS F CG    1 
ATOM   16718 N ND1   . HIS F 1 43  ? -40.699  -36.521  -59.666 1.00 41.21  ? 43   HIS F ND1   1 
ATOM   16719 C CD2   . HIS F 1 43  ? -40.668  -38.494  -58.675 1.00 44.27  ? 43   HIS F CD2   1 
ATOM   16720 C CE1   . HIS F 1 43  ? -39.443  -36.736  -59.239 1.00 44.47  ? 43   HIS F CE1   1 
ATOM   16721 N NE2   . HIS F 1 43  ? -39.400  -37.922  -58.642 1.00 44.81  ? 43   HIS F NE2   1 
ATOM   16722 N N     . ASP F 1 44  ? -43.614  -34.663  -58.454 1.00 29.13  ? 44   ASP F N     1 
ATOM   16723 C CA    . ASP F 1 44  ? -43.113  -33.336  -58.115 1.00 34.74  ? 44   ASP F CA    1 
ATOM   16724 C C     . ASP F 1 44  ? -43.644  -32.901  -56.752 1.00 32.44  ? 44   ASP F C     1 
ATOM   16725 O O     . ASP F 1 44  ? -42.861  -32.440  -55.931 1.00 27.01  ? 44   ASP F O     1 
ATOM   16726 C CB    . ASP F 1 44  ? -43.406  -32.313  -59.205 1.00 38.62  ? 44   ASP F CB    1 
ATOM   16727 C CG    . ASP F 1 44  ? -42.710  -32.584  -60.537 1.00 48.13  ? 44   ASP F CG    1 
ATOM   16728 O OD1   . ASP F 1 44  ? -41.780  -33.435  -60.592 1.00 47.30  ? 44   ASP F OD1   1 
ATOM   16729 O OD2   . ASP F 1 44  ? -43.175  -32.020  -61.541 1.00 54.75  ? 44   ASP F OD2   1 
ATOM   16730 N N     . TYR F 1 45  ? -44.946  -33.124  -56.507 1.00 30.78  ? 45   TYR F N     1 
ATOM   16731 C CA    . TYR F 1 45  ? -45.547  -32.817  -55.224 1.00 32.80  ? 45   TYR F CA    1 
ATOM   16732 C C     . TYR F 1 45  ? -44.839  -33.573  -54.090 1.00 32.89  ? 45   TYR F C     1 
ATOM   16733 O O     . TYR F 1 45  ? -44.488  -32.966  -53.082 1.00 34.39  ? 45   TYR F O     1 
ATOM   16734 C CB    . TYR F 1 45  ? -47.051  -33.087  -55.303 1.00 30.39  ? 45   TYR F CB    1 
ATOM   16735 C CG    . TYR F 1 45  ? -47.759  -32.830  -53.984 1.00 25.86  ? 45   TYR F CG    1 
ATOM   16736 C CD1   . TYR F 1 45  ? -48.181  -31.544  -53.637 1.00 23.93  ? 45   TYR F CD1   1 
ATOM   16737 C CD2   . TYR F 1 45  ? -47.982  -33.860  -53.083 1.00 22.27  ? 45   TYR F CD2   1 
ATOM   16738 C CE1   . TYR F 1 45  ? -48.821  -31.291  -52.428 1.00 23.82  ? 45   TYR F CE1   1 
ATOM   16739 C CE2   . TYR F 1 45  ? -48.629  -33.632  -51.878 1.00 22.75  ? 45   TYR F CE2   1 
ATOM   16740 C CZ    . TYR F 1 45  ? -49.045  -32.347  -51.552 1.00 23.87  ? 45   TYR F CZ    1 
ATOM   16741 O OH    . TYR F 1 45  ? -49.685  -32.135  -50.375 1.00 21.17  ? 45   TYR F OH    1 
ATOM   16742 N N     . GLU F 1 46  ? -44.581  -34.872  -54.274 1.00 28.25  ? 46   GLU F N     1 
ATOM   16743 C CA    . GLU F 1 46  ? -44.001  -35.696  -53.220 1.00 29.03  ? 46   GLU F CA    1 
ATOM   16744 C C     . GLU F 1 46  ? -42.551  -35.308  -52.888 1.00 31.50  ? 46   GLU F C     1 
ATOM   16745 O O     . GLU F 1 46  ? -42.041  -35.659  -51.825 1.00 32.03  ? 46   GLU F O     1 
ATOM   16746 C CB    . GLU F 1 46  ? -44.234  -37.182  -53.474 1.00 25.81  ? 46   GLU F CB    1 
ATOM   16747 C CG    . GLU F 1 46  ? -45.720  -37.510  -53.472 1.00 31.31  ? 46   GLU F CG    1 
ATOM   16748 C CD    . GLU F 1 46  ? -46.019  -38.997  -53.518 1.00 36.82  ? 46   GLU F CD    1 
ATOM   16749 O OE1   . GLU F 1 46  ? -45.049  -39.758  -53.780 1.00 37.66  ? 46   GLU F OE1   1 
ATOM   16750 O OE2   . GLU F 1 46  ? -47.190  -39.423  -53.297 1.00 31.54  ? 46   GLU F OE2   1 
ATOM   16751 N N     . GLN F 1 47  ? -41.905  -34.528  -53.757 1.00 29.96  ? 47   GLN F N     1 
ATOM   16752 C CA    . GLN F 1 47  ? -40.578  -34.000  -53.465 1.00 30.99  ? 47   GLN F CA    1 
ATOM   16753 C C     . GLN F 1 47  ? -40.601  -33.036  -52.272 1.00 29.54  ? 47   GLN F C     1 
ATOM   16754 O O     . GLN F 1 47  ? -39.555  -32.726  -51.710 1.00 30.01  ? 47   GLN F O     1 
ATOM   16755 C CB    . GLN F 1 47  ? -39.988  -33.249  -54.665 1.00 36.41  ? 47   GLN F CB    1 
ATOM   16756 C CG    . GLN F 1 47  ? -39.656  -34.125  -55.877 1.00 39.97  ? 47   GLN F CG    1 
ATOM   16757 C CD    . GLN F 1 47  ? -38.588  -35.149  -55.562 1.00 49.62  ? 47   GLN F CD    1 
ATOM   16758 O OE1   . GLN F 1 47  ? -37.412  -34.839  -55.345 1.00 66.34  ? 47   GLN F OE1   1 
ATOM   16759 N NE2   . GLN F 1 47  ? -39.001  -36.400  -55.494 1.00 49.36  ? 47   GLN F NE2   1 
ATOM   16760 N N     . LEU F 1 48  ? -41.783  -32.533  -51.897 1.00 28.08  ? 48   LEU F N     1 
ATOM   16761 C CA    . LEU F 1 48  ? -41.942  -31.657  -50.744 1.00 25.11  ? 48   LEU F CA    1 
ATOM   16762 C C     . LEU F 1 48  ? -41.430  -32.341  -49.476 1.00 25.07  ? 48   LEU F C     1 
ATOM   16763 O O     . LEU F 1 48  ? -41.101  -31.640  -48.518 1.00 27.34  ? 48   LEU F O     1 
ATOM   16764 C CB    . LEU F 1 48  ? -43.384  -31.177  -50.579 1.00 24.75  ? 48   LEU F CB    1 
ATOM   16765 C CG    . LEU F 1 48  ? -43.885  -30.201  -51.648 1.00 21.35  ? 48   LEU F CG    1 
ATOM   16766 C CD1   . LEU F 1 48  ? -45.388  -29.930  -51.520 1.00 18.07  ? 48   LEU F CD1   1 
ATOM   16767 C CD2   . LEU F 1 48  ? -43.118  -28.897  -51.554 1.00 19.19  ? 48   LEU F CD2   1 
ATOM   16768 N N     . ILE F 1 49  ? -41.327  -33.681  -49.465 1.00 24.19  ? 49   ILE F N     1 
ATOM   16769 C CA    . ILE F 1 49  ? -40.710  -34.359  -48.324 1.00 28.05  ? 49   ILE F CA    1 
ATOM   16770 C C     . ILE F 1 49  ? -39.289  -33.833  -48.068 1.00 30.90  ? 49   ILE F C     1 
ATOM   16771 O O     . ILE F 1 49  ? -38.836  -33.782  -46.927 1.00 35.15  ? 49   ILE F O     1 
ATOM   16772 C CB    . ILE F 1 49  ? -40.741  -35.897  -48.449 1.00 30.64  ? 49   ILE F CB    1 
ATOM   16773 C CG1   . ILE F 1 49  ? -40.403  -36.561  -47.107 1.00 27.73  ? 49   ILE F CG1   1 
ATOM   16774 C CG2   . ILE F 1 49  ? -39.820  -36.411  -49.580 1.00 26.04  ? 49   ILE F CG2   1 
ATOM   16775 C CD1   . ILE F 1 49  ? -40.679  -38.057  -47.089 1.00 25.98  ? 49   ILE F CD1   1 
ATOM   16776 N N     . LYS F 1 50  ? -38.580  -33.416  -49.122 1.00 31.84  ? 50   LYS F N     1 
ATOM   16777 C CA    . LYS F 1 50  ? -37.176  -33.050  -48.984 1.00 33.78  ? 50   LYS F CA    1 
ATOM   16778 C C     . LYS F 1 50  ? -37.014  -31.720  -48.255 1.00 35.15  ? 50   LYS F C     1 
ATOM   16779 O O     . LYS F 1 50  ? -35.938  -31.438  -47.749 1.00 35.57  ? 50   LYS F O     1 
ATOM   16780 C CB    . LYS F 1 50  ? -36.454  -32.968  -50.335 1.00 35.52  ? 50   LYS F CB    1 
ATOM   16781 C CG    . LYS F 1 50  ? -36.269  -34.365  -50.873 1.00 43.39  ? 50   LYS F CG    1 
ATOM   16782 C CD    . LYS F 1 50  ? -35.782  -34.384  -52.311 1.00 56.21  ? 50   LYS F CD    1 
ATOM   16783 C CE    . LYS F 1 50  ? -35.453  -35.827  -52.545 1.00 65.40  ? 50   LYS F CE    1 
ATOM   16784 N NZ    . LYS F 1 50  ? -35.061  -36.030  -53.936 1.00 79.26  ? 50   LYS F NZ    1 
ATOM   16785 N N     . THR F 1 51  ? -38.072  -30.901  -48.216 1.00 31.15  ? 51   THR F N     1 
ATOM   16786 C CA    . THR F 1 51  ? -37.993  -29.605  -47.561 1.00 33.14  ? 51   THR F CA    1 
ATOM   16787 C C     . THR F 1 51  ? -38.867  -29.599  -46.301 1.00 34.56  ? 51   THR F C     1 
ATOM   16788 O O     . THR F 1 51  ? -39.121  -28.544  -45.739 1.00 34.30  ? 51   THR F O     1 
ATOM   16789 C CB    . THR F 1 51  ? -38.319  -28.477  -48.545 1.00 32.21  ? 51   THR F CB    1 
ATOM   16790 O OG1   . THR F 1 51  ? -39.447  -28.955  -49.283 1.00 31.67  ? 51   THR F OG1   1 
ATOM   16791 C CG2   . THR F 1 51  ? -37.204  -28.211  -49.548 1.00 29.29  ? 51   THR F CG2   1 
ATOM   16792 N N     . PHE F 1 52  ? -39.327  -30.781  -45.856 1.00 30.09  ? 52   PHE F N     1 
ATOM   16793 C CA    . PHE F 1 52  ? -40.094  -30.875  -44.627 1.00 28.33  ? 52   PHE F CA    1 
ATOM   16794 C C     . PHE F 1 52  ? -39.123  -30.953  -43.442 1.00 30.02  ? 52   PHE F C     1 
ATOM   16795 O O     . PHE F 1 52  ? -38.784  -32.056  -42.985 1.00 28.54  ? 52   PHE F O     1 
ATOM   16796 C CB    . PHE F 1 52  ? -41.022  -32.094  -44.672 1.00 25.54  ? 52   PHE F CB    1 
ATOM   16797 C CG    . PHE F 1 52  ? -41.995  -32.194  -43.506 1.00 25.44  ? 52   PHE F CG    1 
ATOM   16798 C CD1   . PHE F 1 52  ? -43.164  -31.430  -43.479 1.00 30.11  ? 52   PHE F CD1   1 
ATOM   16799 C CD2   . PHE F 1 52  ? -41.756  -33.049  -42.433 1.00 25.68  ? 52   PHE F CD2   1 
ATOM   16800 C CE1   . PHE F 1 52  ? -44.072  -31.531  -42.426 1.00 29.42  ? 52   PHE F CE1   1 
ATOM   16801 C CE2   . PHE F 1 52  ? -42.648  -33.136  -41.364 1.00 29.07  ? 52   PHE F CE2   1 
ATOM   16802 C CZ    . PHE F 1 52  ? -43.807  -32.382  -41.355 1.00 29.92  ? 52   PHE F CZ    1 
ATOM   16803 N N     . THR F 1 53  ? -38.709  -29.788  -42.922 1.00 27.33  ? 53   THR F N     1 
ATOM   16804 C CA    . THR F 1 53  ? -37.722  -29.715  -41.851 1.00 28.20  ? 53   THR F CA    1 
ATOM   16805 C C     . THR F 1 53  ? -38.390  -29.731  -40.474 1.00 30.39  ? 53   THR F C     1 
ATOM   16806 O O     . THR F 1 53  ? -37.730  -30.021  -39.484 1.00 33.20  ? 53   THR F O     1 
ATOM   16807 C CB    . THR F 1 53  ? -36.898  -28.431  -41.987 1.00 32.46  ? 53   THR F CB    1 
ATOM   16808 O OG1   . THR F 1 53  ? -37.876  -27.412  -41.779 1.00 31.86  ? 53   THR F OG1   1 
ATOM   16809 C CG2   . THR F 1 53  ? -36.222  -28.231  -43.340 1.00 22.96  ? 53   THR F CG2   1 
ATOM   16810 N N     . ALA F 1 54  ? -39.675  -29.342  -40.394 1.00 28.85  ? 54   ALA F N     1 
ATOM   16811 C CA    . ALA F 1 54  ? -40.361  -29.126  -39.132 1.00 25.53  ? 54   ALA F CA    1 
ATOM   16812 C C     . ALA F 1 54  ? -39.581  -28.158  -38.241 1.00 29.54  ? 54   ALA F C     1 
ATOM   16813 O O     . ALA F 1 54  ? -39.679  -28.262  -37.019 1.00 29.40  ? 54   ALA F O     1 
ATOM   16814 C CB    . ALA F 1 54  ? -40.574  -30.423  -38.374 1.00 24.61  ? 54   ALA F CB    1 
ATOM   16815 N N     . ALA F 1 55  ? -38.836  -27.220  -38.845 1.00 27.80  ? 55   ALA F N     1 
ATOM   16816 C CA    . ALA F 1 55  ? -37.929  -26.357  -38.095 1.00 29.78  ? 55   ALA F CA    1 
ATOM   16817 C C     . ALA F 1 55  ? -38.673  -25.499  -37.060 1.00 34.21  ? 55   ALA F C     1 
ATOM   16818 O O     . ALA F 1 55  ? -38.061  -25.029  -36.104 1.00 31.68  ? 55   ALA F O     1 
ATOM   16819 C CB    . ALA F 1 55  ? -37.080  -25.494  -39.034 1.00 22.28  ? 55   ALA F CB    1 
ATOM   16820 N N     . GLN F 1 56  ? -39.978  -25.254  -37.241 1.00 31.69  ? 56   GLN F N     1 
ATOM   16821 C CA    . GLN F 1 56  ? -40.635  -24.385  -36.272 1.00 35.14  ? 56   GLN F CA    1 
ATOM   16822 C C     . GLN F 1 56  ? -41.727  -25.119  -35.506 1.00 31.82  ? 56   GLN F C     1 
ATOM   16823 O O     . GLN F 1 56  ? -42.558  -24.498  -34.869 1.00 35.41  ? 56   GLN F O     1 
ATOM   16824 C CB    . GLN F 1 56  ? -41.167  -23.115  -36.918 1.00 31.94  ? 56   GLN F CB    1 
ATOM   16825 C CG    . GLN F 1 56  ? -40.118  -22.026  -37.035 1.00 40.32  ? 56   GLN F CG    1 
ATOM   16826 C CD    . GLN F 1 56  ? -40.203  -21.373  -38.390 1.00 55.26  ? 56   GLN F CD    1 
ATOM   16827 O OE1   . GLN F 1 56  ? -39.505  -21.799  -39.316 1.00 71.51  ? 56   GLN F OE1   1 
ATOM   16828 N NE2   . GLN F 1 56  ? -41.124  -20.433  -38.560 1.00 48.26  ? 56   GLN F NE2   1 
ATOM   16829 N N     . PHE F 1 57  ? -41.729  -26.438  -35.581 1.00 28.58  ? 57   PHE F N     1 
ATOM   16830 C CA    . PHE F 1 57  ? -42.742  -27.176  -34.857 1.00 29.95  ? 57   PHE F CA    1 
ATOM   16831 C C     . PHE F 1 57  ? -42.274  -27.338  -33.416 1.00 32.18  ? 57   PHE F C     1 
ATOM   16832 O O     . PHE F 1 57  ? -41.231  -27.926  -33.166 1.00 35.03  ? 57   PHE F O     1 
ATOM   16833 C CB    . PHE F 1 57  ? -42.962  -28.550  -35.494 1.00 26.01  ? 57   PHE F CB    1 
ATOM   16834 C CG    . PHE F 1 57  ? -43.993  -29.381  -34.751 1.00 24.76  ? 57   PHE F CG    1 
ATOM   16835 C CD1   . PHE F 1 57  ? -45.353  -29.084  -34.859 1.00 24.90  ? 57   PHE F CD1   1 
ATOM   16836 C CD2   . PHE F 1 57  ? -43.617  -30.468  -33.969 1.00 20.36  ? 57   PHE F CD2   1 
ATOM   16837 C CE1   . PHE F 1 57  ? -46.314  -29.861  -34.209 1.00 25.18  ? 57   PHE F CE1   1 
ATOM   16838 C CE2   . PHE F 1 57  ? -44.573  -31.235  -33.322 1.00 21.00  ? 57   PHE F CE2   1 
ATOM   16839 C CZ    . PHE F 1 57  ? -45.918  -30.942  -33.434 1.00 22.86  ? 57   PHE F CZ    1 
ATOM   16840 N N     . ASP F 1 58  ? -43.059  -26.833  -32.475 1.00 32.90  ? 58   ASP F N     1 
ATOM   16841 C CA    . ASP F 1 58  ? -42.749  -27.008  -31.067 1.00 33.71  ? 58   ASP F CA    1 
ATOM   16842 C C     . ASP F 1 58  ? -43.997  -27.538  -30.361 1.00 31.91  ? 58   ASP F C     1 
ATOM   16843 O O     . ASP F 1 58  ? -44.910  -26.777  -30.070 1.00 31.51  ? 58   ASP F O     1 
ATOM   16844 C CB    . ASP F 1 58  ? -42.212  -25.708  -30.476 1.00 36.27  ? 58   ASP F CB    1 
ATOM   16845 C CG    . ASP F 1 58  ? -41.810  -25.744  -29.007 1.00 38.73  ? 58   ASP F CG    1 
ATOM   16846 O OD1   . ASP F 1 58  ? -42.098  -26.748  -28.301 1.00 38.59  ? 58   ASP F OD1   1 
ATOM   16847 O OD2   . ASP F 1 58  ? -41.234  -24.718  -28.579 1.00 49.11  ? 58   ASP F OD2   1 
ATOM   16848 N N     . ALA F 1 59  ? -44.019  -28.840  -30.087 1.00 30.88  ? 59   ALA F N     1 
ATOM   16849 C CA    . ALA F 1 59  ? -45.226  -29.471  -29.585 1.00 32.23  ? 59   ALA F CA    1 
ATOM   16850 C C     . ALA F 1 59  ? -45.594  -28.886  -28.223 1.00 31.96  ? 59   ALA F C     1 
ATOM   16851 O O     . ALA F 1 59  ? -46.776  -28.827  -27.893 1.00 32.83  ? 59   ALA F O     1 
ATOM   16852 C CB    . ALA F 1 59  ? -45.062  -30.975  -29.506 1.00 27.87  ? 59   ALA F CB    1 
ATOM   16853 N N     . LYS F 1 60  ? -44.595  -28.437  -27.452 1.00 33.60  ? 60   LYS F N     1 
ATOM   16854 C CA    . LYS F 1 60  ? -44.856  -27.886  -26.127 1.00 35.51  ? 60   LYS F CA    1 
ATOM   16855 C C     . LYS F 1 60  ? -45.619  -26.572  -26.273 1.00 33.57  ? 60   LYS F C     1 
ATOM   16856 O O     . LYS F 1 60  ? -46.580  -26.340  -25.539 1.00 33.50  ? 60   LYS F O     1 
ATOM   16857 C CB    . LYS F 1 60  ? -43.600  -27.675  -25.271 1.00 40.62  ? 60   LYS F CB    1 
ATOM   16858 C CG    . LYS F 1 60  ? -42.953  -28.946  -24.785 1.00 52.59  ? 60   LYS F CG    1 
ATOM   16859 C CD    . LYS F 1 60  ? -41.581  -28.784  -24.133 1.00 66.42  ? 60   LYS F CD    1 
ATOM   16860 C CE    . LYS F 1 60  ? -41.169  -30.078  -23.466 1.00 72.66  ? 60   LYS F CE    1 
ATOM   16861 N NZ    . LYS F 1 60  ? -39.722  -30.314  -23.436 1.00 74.49  ? 60   LYS F NZ    1 
ATOM   16862 N N     . LYS F 1 61  ? -45.198  -25.729  -27.236 1.00 29.83  ? 61   LYS F N     1 
ATOM   16863 C CA    . LYS F 1 61  ? -45.884  -24.472  -27.467 1.00 38.26  ? 61   LYS F CA    1 
ATOM   16864 C C     . LYS F 1 61  ? -47.324  -24.734  -27.930 1.00 39.28  ? 61   LYS F C     1 
ATOM   16865 O O     . LYS F 1 61  ? -48.258  -24.055  -27.509 1.00 36.83  ? 61   LYS F O     1 
ATOM   16866 C CB    . LYS F 1 61  ? -45.097  -23.559  -28.407 1.00 44.82  ? 61   LYS F CB    1 
ATOM   16867 C CG    . LYS F 1 61  ? -45.615  -22.172  -28.792 1.00 76.07  ? 61   LYS F CG    1 
ATOM   16868 C CD    . LYS F 1 61  ? -44.627  -21.551  -29.766 1.00 90.06  ? 61   LYS F CD    1 
ATOM   16869 C CE    . LYS F 1 61  ? -43.280  -22.007  -29.257 1.00 104.18 ? 61   LYS F CE    1 
ATOM   16870 N NZ    . LYS F 1 61  ? -42.112  -21.514  -29.989 1.00 102.78 ? 61   LYS F NZ    1 
ATOM   16871 N N     . ILE F 1 62  ? -47.508  -25.737  -28.795 1.00 33.26  ? 62   ILE F N     1 
ATOM   16872 C CA    . ILE F 1 62  ? -48.836  -26.037  -29.298 1.00 29.07  ? 62   ILE F CA    1 
ATOM   16873 C C     . ILE F 1 62  ? -49.737  -26.523  -28.166 1.00 29.44  ? 62   ILE F C     1 
ATOM   16874 O O     . ILE F 1 62  ? -50.866  -26.063  -28.038 1.00 30.16  ? 62   ILE F O     1 
ATOM   16875 C CB    . ILE F 1 62  ? -48.735  -27.014  -30.465 1.00 27.66  ? 62   ILE F CB    1 
ATOM   16876 C CG1   . ILE F 1 62  ? -48.124  -26.247  -31.663 1.00 30.47  ? 62   ILE F CG1   1 
ATOM   16877 C CG2   . ILE F 1 62  ? -50.106  -27.633  -30.788 1.00 26.89  ? 62   ILE F CG2   1 
ATOM   16878 C CD1   . ILE F 1 62  ? -47.785  -27.146  -32.831 1.00 31.78  ? 62   ILE F CD1   1 
ATOM   16879 N N     . ALA F 1 63  ? -49.221  -27.404  -27.305 1.00 27.71  ? 63   ALA F N     1 
ATOM   16880 C CA    . ALA F 1 63  ? -50.018  -27.897  -26.195 1.00 27.93  ? 63   ALA F CA    1 
ATOM   16881 C C     . ALA F 1 63  ? -50.367  -26.754  -25.233 1.00 29.95  ? 63   ALA F C     1 
ATOM   16882 O O     . ALA F 1 63  ? -51.489  -26.676  -24.750 1.00 28.94  ? 63   ALA F O     1 
ATOM   16883 C CB    . ALA F 1 63  ? -49.297  -29.040  -25.492 1.00 25.48  ? 63   ALA F CB    1 
ATOM   16884 N N     . HIS F 1 64  ? -49.411  -25.859  -24.978 1.00 32.01  ? 64   HIS F N     1 
ATOM   16885 C CA    . HIS F 1 64  ? -49.638  -24.713  -24.113 1.00 37.97  ? 64   HIS F CA    1 
ATOM   16886 C C     . HIS F 1 64  ? -50.762  -23.834  -24.690 1.00 38.63  ? 64   HIS F C     1 
ATOM   16887 O O     . HIS F 1 64  ? -51.685  -23.428  -23.990 1.00 36.83  ? 64   HIS F O     1 
ATOM   16888 C CB    . HIS F 1 64  ? -48.328  -23.971  -23.793 1.00 44.04  ? 64   HIS F CB    1 
ATOM   16889 C CG    . HIS F 1 64  ? -48.532  -22.901  -22.758 1.00 72.19  ? 64   HIS F CG    1 
ATOM   16890 N ND1   . HIS F 1 64  ? -48.593  -23.142  -21.391 1.00 86.10  ? 64   HIS F ND1   1 
ATOM   16891 C CD2   . HIS F 1 64  ? -48.740  -21.571  -22.915 1.00 71.80  ? 64   HIS F CD2   1 
ATOM   16892 C CE1   . HIS F 1 64  ? -48.820  -22.000  -20.748 1.00 84.93  ? 64   HIS F CE1   1 
ATOM   16893 N NE2   . HIS F 1 64  ? -48.911  -21.034  -21.656 1.00 84.11  ? 64   HIS F NE2   1 
ATOM   16894 N N     . ALA F 1 65  ? -50.688  -23.539  -25.989 1.00 32.87  ? 65   ALA F N     1 
ATOM   16895 C CA    . ALA F 1 65  ? -51.699  -22.730  -26.637 1.00 29.39  ? 65   ALA F CA    1 
ATOM   16896 C C     . ALA F 1 65  ? -53.078  -23.411  -26.548 1.00 28.70  ? 65   ALA F C     1 
ATOM   16897 O O     . ALA F 1 65  ? -54.078  -22.761  -26.274 1.00 34.96  ? 65   ALA F O     1 
ATOM   16898 C CB    . ALA F 1 65  ? -51.261  -22.407  -28.046 1.00 24.94  ? 65   ALA F CB    1 
ATOM   16899 N N     . ALA F 1 66  ? -53.146  -24.718  -26.731 1.00 25.62  ? 66   ALA F N     1 
ATOM   16900 C CA    . ALA F 1 66  ? -54.404  -25.441  -26.572 1.00 28.08  ? 66   ALA F CA    1 
ATOM   16901 C C     . ALA F 1 66  ? -54.970  -25.316  -25.148 1.00 30.04  ? 66   ALA F C     1 
ATOM   16902 O O     . ALA F 1 66  ? -56.168  -25.105  -24.951 1.00 29.42  ? 66   ALA F O     1 
ATOM   16903 C CB    . ALA F 1 66  ? -54.229  -26.880  -26.994 1.00 21.79  ? 66   ALA F CB    1 
ATOM   16904 N N     . LYS F 1 67  ? -54.087  -25.432  -24.152 1.00 30.32  ? 67   LYS F N     1 
ATOM   16905 C CA    . LYS F 1 67  ? -54.482  -25.268  -22.755 1.00 39.77  ? 67   LYS F CA    1 
ATOM   16906 C C     . LYS F 1 67  ? -55.032  -23.856  -22.523 1.00 33.30  ? 67   LYS F C     1 
ATOM   16907 O O     . LYS F 1 67  ? -56.094  -23.719  -21.941 1.00 35.77  ? 67   LYS F O     1 
ATOM   16908 C CB    . LYS F 1 67  ? -53.341  -25.604  -21.782 1.00 37.70  ? 67   LYS F CB    1 
ATOM   16909 C CG    . LYS F 1 67  ? -53.682  -25.517  -20.304 1.00 36.57  ? 67   LYS F CG    1 
ATOM   16910 C CD    . LYS F 1 67  ? -53.929  -26.888  -19.701 1.00 50.91  ? 67   LYS F CD    1 
ATOM   16911 C CE    . LYS F 1 67  ? -53.441  -27.005  -18.271 1.00 52.68  ? 67   LYS F CE    1 
ATOM   16912 N NZ    . LYS F 1 67  ? -54.160  -28.206  -17.835 1.00 47.28  ? 67   LYS F NZ    1 
ATOM   16913 N N     . ALA F 1 68  ? -54.339  -22.828  -23.021 1.00 28.41  ? 68   ALA F N     1 
ATOM   16914 C CA    . ALA F 1 68  ? -54.722  -21.426  -22.837 1.00 32.46  ? 68   ALA F CA    1 
ATOM   16915 C C     . ALA F 1 68  ? -56.068  -21.146  -23.493 1.00 34.35  ? 68   ALA F C     1 
ATOM   16916 O O     . ALA F 1 68  ? -56.830  -20.333  -22.986 1.00 40.18  ? 68   ALA F O     1 
ATOM   16917 C CB    . ALA F 1 68  ? -53.662  -20.471  -23.385 1.00 27.60  ? 68   ALA F CB    1 
ATOM   16918 N N     . VAL F 1 69  ? -56.374  -21.820  -24.612 1.00 31.19  ? 69   VAL F N     1 
ATOM   16919 C CA    . VAL F 1 69  ? -57.602  -21.523  -25.324 1.00 29.17  ? 69   VAL F CA    1 
ATOM   16920 C C     . VAL F 1 69  ? -58.759  -22.272  -24.649 1.00 32.17  ? 69   VAL F C     1 
ATOM   16921 O O     . VAL F 1 69  ? -59.919  -22.088  -25.041 1.00 31.59  ? 69   VAL F O     1 
ATOM   16922 C CB    . VAL F 1 69  ? -57.496  -21.837  -26.828 1.00 28.65  ? 69   VAL F CB    1 
ATOM   16923 C CG1   . VAL F 1 69  ? -57.723  -23.321  -27.130 1.00 29.64  ? 69   VAL F CG1   1 
ATOM   16924 C CG2   . VAL F 1 69  ? -58.544  -21.086  -27.627 1.00 37.84  ? 69   VAL F CG2   1 
ATOM   16925 N N     . GLY F 1 70  ? -58.453  -23.121  -23.643 1.00 27.39  ? 70   GLY F N     1 
ATOM   16926 C CA    . GLY F 1 70  ? -59.477  -23.898  -22.948 1.00 27.67  ? 70   GLY F CA    1 
ATOM   16927 C C     . GLY F 1 70  ? -59.852  -25.217  -23.633 1.00 29.20  ? 70   GLY F C     1 
ATOM   16928 O O     . GLY F 1 70  ? -60.848  -25.840  -23.256 1.00 31.48  ? 70   GLY F O     1 
ATOM   16929 N N     . ALA F 1 71  ? -59.048  -25.675  -24.611 1.00 28.19  ? 71   ALA F N     1 
ATOM   16930 C CA    . ALA F 1 71  ? -59.257  -26.983  -25.216 1.00 26.53  ? 71   ALA F CA    1 
ATOM   16931 C C     . ALA F 1 71  ? -58.814  -28.071  -24.230 1.00 29.67  ? 71   ALA F C     1 
ATOM   16932 O O     . ALA F 1 71  ? -57.889  -27.860  -23.426 1.00 29.08  ? 71   ALA F O     1 
ATOM   16933 C CB    . ALA F 1 71  ? -58.486  -27.086  -26.527 1.00 24.25  ? 71   ALA F CB    1 
ATOM   16934 N N     . LYS F 1 72  ? -59.471  -29.244  -24.297 1.00 25.15  ? 72   LYS F N     1 
ATOM   16935 C CA    . LYS F 1 72  ? -59.101  -30.361  -23.441 1.00 27.06  ? 72   LYS F CA    1 
ATOM   16936 C C     . LYS F 1 72  ? -58.511  -31.521  -24.261 1.00 27.69  ? 72   LYS F C     1 
ATOM   16937 O O     . LYS F 1 72  ? -58.122  -32.544  -23.686 1.00 26.66  ? 72   LYS F O     1 
ATOM   16938 C CB    . LYS F 1 72  ? -60.331  -30.808  -22.648 1.00 27.96  ? 72   LYS F CB    1 
ATOM   16939 C CG    . LYS F 1 72  ? -60.813  -29.791  -21.609 1.00 33.97  ? 72   LYS F CG    1 
ATOM   16940 C CD    . LYS F 1 72  ? -59.765  -29.429  -20.565 1.00 38.62  ? 72   LYS F CD    1 
ATOM   16941 C CE    . LYS F 1 72  ? -60.100  -28.457  -19.483 1.00 42.97  ? 72   LYS F CE    1 
ATOM   16942 N NZ    . LYS F 1 72  ? -61.259  -28.956  -18.732 1.00 48.63  ? 72   LYS F NZ    1 
ATOM   16943 N N     . TYR F 1 73  ? -58.482  -31.375  -25.596 1.00 24.71  ? 73   TYR F N     1 
ATOM   16944 C CA    . TYR F 1 73  ? -57.887  -32.372  -26.464 1.00 25.11  ? 73   TYR F CA    1 
ATOM   16945 C C     . TYR F 1 73  ? -57.438  -31.709  -27.761 1.00 27.78  ? 73   TYR F C     1 
ATOM   16946 O O     . TYR F 1 73  ? -57.895  -30.611  -28.078 1.00 24.93  ? 73   TYR F O     1 
ATOM   16947 C CB    . TYR F 1 73  ? -58.824  -33.546  -26.744 1.00 24.08  ? 73   TYR F CB    1 
ATOM   16948 C CG    . TYR F 1 73  ? -60.138  -33.308  -27.481 1.00 25.58  ? 73   TYR F CG    1 
ATOM   16949 C CD1   . TYR F 1 73  ? -61.141  -32.499  -26.948 1.00 24.09  ? 73   TYR F CD1   1 
ATOM   16950 C CD2   . TYR F 1 73  ? -60.408  -33.957  -28.689 1.00 24.36  ? 73   TYR F CD2   1 
ATOM   16951 C CE1   . TYR F 1 73  ? -62.362  -32.351  -27.594 1.00 24.03  ? 73   TYR F CE1   1 
ATOM   16952 C CE2   . TYR F 1 73  ? -61.630  -33.827  -29.339 1.00 26.66  ? 73   TYR F CE2   1 
ATOM   16953 C CZ    . TYR F 1 73  ? -62.609  -33.020  -28.784 1.00 26.95  ? 73   TYR F CZ    1 
ATOM   16954 O OH    . TYR F 1 73  ? -63.823  -32.906  -29.410 1.00 27.29  ? 73   TYR F OH    1 
ATOM   16955 N N     . ILE F 1 74  ? -56.525  -32.391  -28.476 1.00 23.36  ? 74   ILE F N     1 
ATOM   16956 C CA    . ILE F 1 74  ? -56.020  -31.938  -29.756 1.00 23.85  ? 74   ILE F CA    1 
ATOM   16957 C C     . ILE F 1 74  ? -56.114  -33.095  -30.748 1.00 26.60  ? 74   ILE F C     1 
ATOM   16958 O O     . ILE F 1 74  ? -55.700  -34.213  -30.437 1.00 25.44  ? 74   ILE F O     1 
ATOM   16959 C CB    . ILE F 1 74  ? -54.578  -31.437  -29.644 1.00 24.74  ? 74   ILE F CB    1 
ATOM   16960 C CG1   . ILE F 1 74  ? -54.405  -30.373  -28.574 1.00 24.43  ? 74   ILE F CG1   1 
ATOM   16961 C CG2   . ILE F 1 74  ? -54.104  -30.917  -31.005 1.00 22.41  ? 74   ILE F CG2   1 
ATOM   16962 C CD1   . ILE F 1 74  ? -52.932  -30.009  -28.336 1.00 22.22  ? 74   ILE F CD1   1 
ATOM   16963 N N     . VAL F 1 75  ? -56.683  -32.807  -31.925 1.00 23.65  ? 75   VAL F N     1 
ATOM   16964 C CA    . VAL F 1 75  ? -56.694  -33.747  -33.021 1.00 22.92  ? 75   VAL F CA    1 
ATOM   16965 C C     . VAL F 1 75  ? -55.639  -33.294  -34.020 1.00 24.28  ? 75   VAL F C     1 
ATOM   16966 O O     . VAL F 1 75  ? -55.798  -32.221  -34.607 1.00 27.43  ? 75   VAL F O     1 
ATOM   16967 C CB    . VAL F 1 75  ? -58.092  -33.792  -33.662 1.00 20.47  ? 75   VAL F CB    1 
ATOM   16968 C CG1   . VAL F 1 75  ? -58.125  -34.828  -34.791 1.00 19.67  ? 75   VAL F CG1   1 
ATOM   16969 C CG2   . VAL F 1 75  ? -59.156  -34.123  -32.629 1.00 17.98  ? 75   VAL F CG2   1 
ATOM   16970 N N     . LEU F 1 76  ? -54.572  -34.109  -34.189 1.00 23.15  ? 76   LEU F N     1 
ATOM   16971 C CA    . LEU F 1 76  ? -53.483  -33.803  -35.111 1.00 24.01  ? 76   LEU F CA    1 
ATOM   16972 C C     . LEU F 1 76  ? -53.570  -34.709  -36.338 1.00 24.35  ? 76   LEU F C     1 
ATOM   16973 O O     . LEU F 1 76  ? -53.789  -35.919  -36.206 1.00 26.44  ? 76   LEU F O     1 
ATOM   16974 C CB    . LEU F 1 76  ? -52.136  -33.928  -34.410 1.00 22.55  ? 76   LEU F CB    1 
ATOM   16975 C CG    . LEU F 1 76  ? -50.899  -33.650  -35.273 1.00 25.05  ? 76   LEU F CG    1 
ATOM   16976 C CD1   . LEU F 1 76  ? -50.887  -32.253  -35.870 1.00 19.89  ? 76   LEU F CD1   1 
ATOM   16977 C CD2   . LEU F 1 76  ? -49.631  -33.810  -34.419 1.00 25.27  ? 76   LEU F CD2   1 
ATOM   16978 N N     . THR F 1 77  ? -53.426  -34.120  -37.539 1.00 20.06  ? 77   THR F N     1 
ATOM   16979 C CA    . THR F 1 77  ? -53.370  -34.926  -38.748 1.00 24.87  ? 77   THR F CA    1 
ATOM   16980 C C     . THR F 1 77  ? -52.092  -35.777  -38.739 1.00 25.44  ? 77   THR F C     1 
ATOM   16981 O O     . THR F 1 77  ? -51.008  -35.236  -38.930 1.00 27.24  ? 77   THR F O     1 
ATOM   16982 C CB    . THR F 1 77  ? -53.429  -34.024  -39.986 1.00 24.08  ? 77   THR F CB    1 
ATOM   16983 O OG1   . THR F 1 77  ? -52.403  -33.033  -39.878 1.00 22.60  ? 77   THR F OG1   1 
ATOM   16984 C CG2   . THR F 1 77  ? -54.788  -33.380  -40.212 1.00 23.26  ? 77   THR F CG2   1 
ATOM   16985 N N     . THR F 1 78  ? -52.206  -37.097  -38.529 1.00 25.41  ? 78   THR F N     1 
ATOM   16986 C CA    . THR F 1 78  ? -51.003  -37.939  -38.535 1.00 26.90  ? 78   THR F CA    1 
ATOM   16987 C C     . THR F 1 78  ? -50.679  -38.415  -39.958 1.00 26.40  ? 78   THR F C     1 
ATOM   16988 O O     . THR F 1 78  ? -49.524  -38.732  -40.251 1.00 25.49  ? 78   THR F O     1 
ATOM   16989 C CB    . THR F 1 78  ? -51.132  -39.130  -37.590 1.00 25.93  ? 78   THR F CB    1 
ATOM   16990 O OG1   . THR F 1 78  ? -52.080  -40.020  -38.182 1.00 24.40  ? 78   THR F OG1   1 
ATOM   16991 C CG2   . THR F 1 78  ? -51.511  -38.727  -36.175 1.00 23.82  ? 78   THR F CG2   1 
ATOM   16992 N N     . LYS F 1 79  ? -51.714  -38.462  -40.825 1.00 23.78  ? 79   LYS F N     1 
ATOM   16993 C CA    . LYS F 1 79  ? -51.573  -38.722  -42.250 1.00 21.49  ? 79   LYS F CA    1 
ATOM   16994 C C     . LYS F 1 79  ? -52.842  -38.228  -42.948 1.00 23.23  ? 79   LYS F C     1 
ATOM   16995 O O     . LYS F 1 79  ? -53.938  -38.710  -42.642 1.00 25.73  ? 79   LYS F O     1 
ATOM   16996 C CB    . LYS F 1 79  ? -51.420  -40.224  -42.529 1.00 18.49  ? 79   LYS F CB    1 
ATOM   16997 C CG    . LYS F 1 79  ? -51.078  -40.599  -43.967 1.00 20.14  ? 79   LYS F CG    1 
ATOM   16998 C CD    . LYS F 1 79  ? -51.603  -41.940  -44.481 1.00 19.47  ? 79   LYS F CD    1 
ATOM   16999 C CE    . LYS F 1 79  ? -53.099  -41.945  -44.666 1.00 21.73  ? 79   LYS F CE    1 
ATOM   17000 N NZ    . LYS F 1 79  ? -53.651  -43.186  -45.219 1.00 20.57  ? 79   LYS F NZ    1 
ATOM   17001 N N     . HIS F 1 80  ? -52.697  -37.269  -43.878 1.00 22.17  ? 80   HIS F N     1 
ATOM   17002 C CA    . HIS F 1 80  ? -53.833  -36.750  -44.637 1.00 22.53  ? 80   HIS F CA    1 
ATOM   17003 C C     . HIS F 1 80  ? -53.947  -37.499  -45.982 1.00 26.38  ? 80   HIS F C     1 
ATOM   17004 O O     . HIS F 1 80  ? -53.235  -38.480  -46.213 1.00 25.84  ? 80   HIS F O     1 
ATOM   17005 C CB    . HIS F 1 80  ? -53.741  -35.218  -44.712 1.00 21.72  ? 80   HIS F CB    1 
ATOM   17006 C CG    . HIS F 1 80  ? -55.091  -34.581  -44.823 1.00 27.75  ? 80   HIS F CG    1 
ATOM   17007 N ND1   . HIS F 1 80  ? -55.740  -34.366  -46.031 1.00 26.33  ? 80   HIS F ND1   1 
ATOM   17008 C CD2   . HIS F 1 80  ? -55.951  -34.159  -43.864 1.00 27.02  ? 80   HIS F CD2   1 
ATOM   17009 C CE1   . HIS F 1 80  ? -56.923  -33.818  -45.795 1.00 24.00  ? 80   HIS F CE1   1 
ATOM   17010 N NE2   . HIS F 1 80  ? -57.075  -33.689  -44.495 1.00 23.73  ? 80   HIS F NE2   1 
ATOM   17011 N N     . HIS F 1 81  ? -54.836  -37.046  -46.884 1.00 24.79  ? 81   HIS F N     1 
ATOM   17012 C CA    . HIS F 1 81  ? -55.025  -37.734  -48.157 1.00 25.37  ? 81   HIS F CA    1 
ATOM   17013 C C     . HIS F 1 81  ? -53.712  -37.865  -48.933 1.00 25.51  ? 81   HIS F C     1 
ATOM   17014 O O     . HIS F 1 81  ? -53.490  -38.859  -49.622 1.00 25.63  ? 81   HIS F O     1 
ATOM   17015 C CB    . HIS F 1 81  ? -56.077  -37.031  -49.022 1.00 27.13  ? 81   HIS F CB    1 
ATOM   17016 C CG    . HIS F 1 81  ? -57.396  -36.870  -48.334 1.00 30.15  ? 81   HIS F CG    1 
ATOM   17017 N ND1   . HIS F 1 81  ? -58.016  -37.919  -47.699 1.00 31.27  ? 81   HIS F ND1   1 
ATOM   17018 C CD2   . HIS F 1 81  ? -58.216  -35.812  -48.167 1.00 28.08  ? 81   HIS F CD2   1 
ATOM   17019 C CE1   . HIS F 1 81  ? -59.154  -37.496  -47.162 1.00 29.01  ? 81   HIS F CE1   1 
ATOM   17020 N NE2   . HIS F 1 81  ? -59.303  -36.236  -47.448 1.00 25.89  ? 81   HIS F NE2   1 
ATOM   17021 N N     . GLU F 1 82  ? -52.846  -36.854  -48.855 1.00 22.39  ? 82   GLU F N     1 
ATOM   17022 C CA    . GLU F 1 82  ? -51.592  -36.885  -49.583 1.00 23.36  ? 82   GLU F CA    1 
ATOM   17023 C C     . GLU F 1 82  ? -50.771  -38.119  -49.173 1.00 25.02  ? 82   GLU F C     1 
ATOM   17024 O O     . GLU F 1 82  ? -49.855  -38.496  -49.885 1.00 23.40  ? 82   GLU F O     1 
ATOM   17025 C CB    . GLU F 1 82  ? -50.775  -35.616  -49.317 1.00 26.14  ? 82   GLU F CB    1 
ATOM   17026 C CG    . GLU F 1 82  ? -50.496  -35.384  -47.827 1.00 24.24  ? 82   GLU F CG    1 
ATOM   17027 C CD    . GLU F 1 82  ? -49.553  -34.266  -47.425 1.00 25.27  ? 82   GLU F CD    1 
ATOM   17028 O OE1   . GLU F 1 82  ? -49.262  -33.357  -48.251 1.00 24.73  ? 82   GLU F OE1   1 
ATOM   17029 O OE2   . GLU F 1 82  ? -49.077  -34.319  -46.260 1.00 25.98  ? 82   GLU F OE2   1 
ATOM   17030 N N     . GLY F 1 83  ? -51.034  -38.701  -47.999 1.00 24.12  ? 83   GLY F N     1 
ATOM   17031 C CA    . GLY F 1 83  ? -50.514  -40.019  -47.653 1.00 22.43  ? 83   GLY F CA    1 
ATOM   17032 C C     . GLY F 1 83  ? -49.164  -39.972  -46.949 1.00 27.02  ? 83   GLY F C     1 
ATOM   17033 O O     . GLY F 1 83  ? -48.567  -41.029  -46.736 1.00 23.73  ? 83   GLY F O     1 
ATOM   17034 N N     . PHE F 1 84  ? -48.681  -38.761  -46.585 1.00 24.71  ? 84   PHE F N     1 
ATOM   17035 C CA    . PHE F 1 84  ? -47.417  -38.612  -45.871 1.00 22.55  ? 84   PHE F CA    1 
ATOM   17036 C C     . PHE F 1 84  ? -47.625  -38.748  -44.365 1.00 25.06  ? 84   PHE F C     1 
ATOM   17037 O O     . PHE F 1 84  ? -48.520  -38.127  -43.797 1.00 26.92  ? 84   PHE F O     1 
ATOM   17038 C CB    . PHE F 1 84  ? -46.876  -37.230  -46.227 1.00 24.13  ? 84   PHE F CB    1 
ATOM   17039 C CG    . PHE F 1 84  ? -45.679  -36.838  -45.372 1.00 28.63  ? 84   PHE F CG    1 
ATOM   17040 C CD1   . PHE F 1 84  ? -44.424  -37.433  -45.563 1.00 25.80  ? 84   PHE F CD1   1 
ATOM   17041 C CD2   . PHE F 1 84  ? -45.809  -35.877  -44.369 1.00 28.99  ? 84   PHE F CD2   1 
ATOM   17042 C CE1   . PHE F 1 84  ? -43.332  -37.059  -44.786 1.00 26.44  ? 84   PHE F CE1   1 
ATOM   17043 C CE2   . PHE F 1 84  ? -44.709  -35.507  -43.582 1.00 29.31  ? 84   PHE F CE2   1 
ATOM   17044 C CZ    . PHE F 1 84  ? -43.478  -36.108  -43.785 1.00 27.04  ? 84   PHE F CZ    1 
ATOM   17045 N N     . PHE F 1 85  ? -46.773  -39.532  -43.699 1.00 24.15  ? 85   PHE F N     1 
ATOM   17046 C CA    . PHE F 1 85  ? -46.971  -39.827  -42.288 1.00 23.82  ? 85   PHE F CA    1 
ATOM   17047 C C     . PHE F 1 85  ? -46.059  -38.964  -41.413 1.00 26.24  ? 85   PHE F C     1 
ATOM   17048 O O     . PHE F 1 85  ? -44.852  -38.870  -41.647 1.00 25.74  ? 85   PHE F O     1 
ATOM   17049 C CB    . PHE F 1 85  ? -46.623  -41.281  -41.985 1.00 20.98  ? 85   PHE F CB    1 
ATOM   17050 C CG    . PHE F 1 85  ? -47.421  -42.336  -42.738 1.00 22.51  ? 85   PHE F CG    1 
ATOM   17051 C CD1   . PHE F 1 85  ? -47.014  -42.774  -44.009 1.00 21.09  ? 85   PHE F CD1   1 
ATOM   17052 C CD2   . PHE F 1 85  ? -48.524  -42.938  -42.139 1.00 21.20  ? 85   PHE F CD2   1 
ATOM   17053 C CE1   . PHE F 1 85  ? -47.716  -43.756  -44.680 1.00 19.99  ? 85   PHE F CE1   1 
ATOM   17054 C CE2   . PHE F 1 85  ? -49.248  -43.906  -42.817 1.00 21.17  ? 85   PHE F CE2   1 
ATOM   17055 C CZ    . PHE F 1 85  ? -48.828  -44.324  -44.084 1.00 20.90  ? 85   PHE F CZ    1 
ATOM   17056 N N     . LEU F 1 86  ? -46.647  -38.376  -40.369 1.00 22.22  ? 86   LEU F N     1 
ATOM   17057 C CA    . LEU F 1 86  ? -45.905  -37.483  -39.493 1.00 24.21  ? 86   LEU F CA    1 
ATOM   17058 C C     . LEU F 1 86  ? -45.230  -38.264  -38.364 1.00 26.35  ? 86   LEU F C     1 
ATOM   17059 O O     . LEU F 1 86  ? -44.734  -37.666  -37.413 1.00 27.92  ? 86   LEU F O     1 
ATOM   17060 C CB    . LEU F 1 86  ? -46.825  -36.385  -38.959 1.00 24.11  ? 86   LEU F CB    1 
ATOM   17061 C CG    . LEU F 1 86  ? -47.000  -35.154  -39.854 1.00 24.27  ? 86   LEU F CG    1 
ATOM   17062 C CD1   . LEU F 1 86  ? -47.835  -35.429  -41.075 1.00 22.94  ? 86   LEU F CD1   1 
ATOM   17063 C CD2   . LEU F 1 86  ? -47.659  -34.097  -38.965 1.00 23.23  ? 86   LEU F CD2   1 
ATOM   17064 N N     . TYR F 1 87  ? -45.198  -39.599  -38.473 1.00 25.78  ? 87   TYR F N     1 
ATOM   17065 C CA    . TYR F 1 87  ? -44.560  -40.421  -37.459 1.00 27.08  ? 87   TYR F CA    1 
ATOM   17066 C C     . TYR F 1 87  ? -43.710  -41.520  -38.110 1.00 31.27  ? 87   TYR F C     1 
ATOM   17067 O O     . TYR F 1 87  ? -43.754  -41.721  -39.318 1.00 27.12  ? 87   TYR F O     1 
ATOM   17068 C CB    . TYR F 1 87  ? -45.638  -41.021  -36.548 1.00 24.57  ? 87   TYR F CB    1 
ATOM   17069 C CG    . TYR F 1 87  ? -46.693  -41.872  -37.244 1.00 26.12  ? 87   TYR F CG    1 
ATOM   17070 C CD1   . TYR F 1 87  ? -47.746  -41.286  -37.941 1.00 22.97  ? 87   TYR F CD1   1 
ATOM   17071 C CD2   . TYR F 1 87  ? -46.655  -43.267  -37.184 1.00 25.12  ? 87   TYR F CD2   1 
ATOM   17072 C CE1   . TYR F 1 87  ? -48.730  -42.058  -38.552 1.00 24.36  ? 87   TYR F CE1   1 
ATOM   17073 C CE2   . TYR F 1 87  ? -47.653  -44.042  -37.759 1.00 23.89  ? 87   TYR F CE2   1 
ATOM   17074 C CZ    . TYR F 1 87  ? -48.700  -43.437  -38.447 1.00 26.93  ? 87   TYR F CZ    1 
ATOM   17075 O OH    . TYR F 1 87  ? -49.681  -44.196  -39.046 1.00 25.47  ? 87   TYR F OH    1 
ATOM   17076 N N     . ASP F 1 88  ? -42.966  -42.263  -37.274 1.00 32.34  ? 88   ASP F N     1 
ATOM   17077 C CA    . ASP F 1 88  ? -42.133  -43.354  -37.735 1.00 31.54  ? 88   ASP F CA    1 
ATOM   17078 C C     . ASP F 1 88  ? -43.003  -44.577  -38.029 1.00 28.90  ? 88   ASP F C     1 
ATOM   17079 O O     . ASP F 1 88  ? -43.510  -45.217  -37.111 1.00 26.08  ? 88   ASP F O     1 
ATOM   17080 C CB    . ASP F 1 88  ? -41.097  -43.696  -36.683 1.00 36.30  ? 88   ASP F CB    1 
ATOM   17081 C CG    . ASP F 1 88  ? -40.055  -44.740  -37.087 1.00 36.93  ? 88   ASP F CG    1 
ATOM   17082 O OD1   . ASP F 1 88  ? -40.255  -45.476  -38.097 1.00 35.27  ? 88   ASP F OD1   1 
ATOM   17083 O OD2   . ASP F 1 88  ? -39.037  -44.808  -36.380 1.00 42.76  ? 88   ASP F OD2   1 
ATOM   17084 N N     . THR F 1 89  ? -43.130  -44.931  -39.311 1.00 26.43  ? 89   THR F N     1 
ATOM   17085 C CA    . THR F 1 89  ? -44.003  -46.041  -39.660 1.00 30.19  ? 89   THR F CA    1 
ATOM   17086 C C     . THR F 1 89  ? -43.286  -47.381  -39.513 1.00 34.92  ? 89   THR F C     1 
ATOM   17087 O O     . THR F 1 89  ? -43.881  -48.407  -39.872 1.00 41.03  ? 89   THR F O     1 
ATOM   17088 C CB    . THR F 1 89  ? -44.595  -45.880  -41.060 1.00 31.01  ? 89   THR F CB    1 
ATOM   17089 O OG1   . THR F 1 89  ? -43.505  -45.958  -41.980 1.00 28.96  ? 89   THR F OG1   1 
ATOM   17090 C CG2   . THR F 1 89  ? -45.322  -44.553  -41.227 1.00 29.33  ? 89   THR F CG2   1 
ATOM   17091 N N     . LYS F 1 90  ? -42.020  -47.367  -39.043 1.00 33.51  ? 90   LYS F N     1 
ATOM   17092 C CA    . LYS F 1 90  ? -41.287  -48.582  -38.690 1.00 36.20  ? 90   LYS F CA    1 
ATOM   17093 C C     . LYS F 1 90  ? -41.242  -49.570  -39.866 1.00 37.17  ? 90   LYS F C     1 
ATOM   17094 O O     . LYS F 1 90  ? -41.520  -50.753  -39.688 1.00 35.19  ? 90   LYS F O     1 
ATOM   17095 C CB    . LYS F 1 90  ? -41.906  -49.299  -37.489 1.00 30.95  ? 90   LYS F CB    1 
ATOM   17096 C CG    . LYS F 1 90  ? -41.992  -48.421  -36.262 1.00 39.37  ? 90   LYS F CG    1 
ATOM   17097 C CD    . LYS F 1 90  ? -42.438  -49.196  -35.024 1.00 59.03  ? 90   LYS F CD    1 
ATOM   17098 C CE    . LYS F 1 90  ? -41.288  -49.496  -34.106 1.00 69.08  ? 90   LYS F CE    1 
ATOM   17099 N NZ    . LYS F 1 90  ? -40.420  -48.304  -34.065 1.00 76.97  ? 90   LYS F NZ    1 
ATOM   17100 N N     . GLY F 1 91  ? -40.944  -49.064  -41.076 1.00 33.62  ? 91   GLY F N     1 
ATOM   17101 C CA    . GLY F 1 91  ? -40.784  -49.947  -42.219 1.00 30.35  ? 91   GLY F CA    1 
ATOM   17102 C C     . GLY F 1 91  ? -42.018  -49.987  -43.119 1.00 36.85  ? 91   GLY F C     1 
ATOM   17103 O O     . GLY F 1 91  ? -41.905  -50.426  -44.263 1.00 37.61  ? 91   GLY F O     1 
ATOM   17104 N N     . LEU F 1 92  ? -43.184  -49.521  -42.649 1.00 32.65  ? 92   LEU F N     1 
ATOM   17105 C CA    . LEU F 1 92  ? -44.351  -49.632  -43.502 1.00 32.13  ? 92   LEU F CA    1 
ATOM   17106 C C     . LEU F 1 92  ? -44.210  -48.765  -44.757 1.00 32.35  ? 92   LEU F C     1 
ATOM   17107 O O     . LEU F 1 92  ? -44.687  -49.151  -45.819 1.00 31.76  ? 92   LEU F O     1 
ATOM   17108 C CB    . LEU F 1 92  ? -45.619  -49.282  -42.740 1.00 35.14  ? 92   LEU F CB    1 
ATOM   17109 C CG    . LEU F 1 92  ? -46.896  -49.320  -43.584 1.00 38.32  ? 92   LEU F CG    1 
ATOM   17110 C CD1   . LEU F 1 92  ? -47.249  -50.769  -43.923 1.00 38.57  ? 92   LEU F CD1   1 
ATOM   17111 C CD2   . LEU F 1 92  ? -48.033  -48.620  -42.849 1.00 28.49  ? 92   LEU F CD2   1 
ATOM   17112 N N     . SER F 1 93  ? -43.573  -47.593  -44.641 1.00 27.89  ? 93   SER F N     1 
ATOM   17113 C CA    . SER F 1 93  ? -43.511  -46.679  -45.766 1.00 29.27  ? 93   SER F CA    1 
ATOM   17114 C C     . SER F 1 93  ? -42.241  -45.834  -45.674 1.00 29.07  ? 93   SER F C     1 
ATOM   17115 O O     . SER F 1 93  ? -41.788  -45.506  -44.602 1.00 29.90  ? 93   SER F O     1 
ATOM   17116 C CB    . SER F 1 93  ? -44.750  -45.778  -45.793 1.00 30.86  ? 93   SER F CB    1 
ATOM   17117 O OG    . SER F 1 93  ? -44.591  -44.740  -46.750 1.00 28.87  ? 93   SER F OG    1 
ATOM   17118 N N     . ASP F 1 94  ? -41.691  -45.437  -46.811 1.00 30.13  ? 94   ASP F N     1 
ATOM   17119 C CA    . ASP F 1 94  ? -40.598  -44.494  -46.877 1.00 35.19  ? 94   ASP F CA    1 
ATOM   17120 C C     . ASP F 1 94  ? -41.102  -43.051  -46.909 1.00 36.67  ? 94   ASP F C     1 
ATOM   17121 O O     . ASP F 1 94  ? -40.301  -42.118  -46.855 1.00 39.60  ? 94   ASP F O     1 
ATOM   17122 C CB    . ASP F 1 94  ? -39.819  -44.732  -48.163 1.00 43.42  ? 94   ASP F CB    1 
ATOM   17123 C CG    . ASP F 1 94  ? -38.904  -45.949  -48.147 1.00 53.84  ? 94   ASP F CG    1 
ATOM   17124 O OD1   . ASP F 1 94  ? -38.659  -46.484  -47.038 1.00 55.52  ? 94   ASP F OD1   1 
ATOM   17125 O OD2   . ASP F 1 94  ? -38.435  -46.347  -49.241 1.00 56.68  ? 94   ASP F OD2   1 
ATOM   17126 N N     . PHE F 1 95  ? -42.419  -42.870  -47.080 1.00 32.66  ? 95   PHE F N     1 
ATOM   17127 C CA    . PHE F 1 95  ? -42.991  -41.539  -47.208 1.00 30.90  ? 95   PHE F CA    1 
ATOM   17128 C C     . PHE F 1 95  ? -43.428  -41.061  -45.821 1.00 28.18  ? 95   PHE F C     1 
ATOM   17129 O O     . PHE F 1 95  ? -44.620  -40.929  -45.551 1.00 30.15  ? 95   PHE F O     1 
ATOM   17130 C CB    . PHE F 1 95  ? -44.120  -41.655  -48.233 1.00 26.88  ? 95   PHE F CB    1 
ATOM   17131 C CG    . PHE F 1 95  ? -44.592  -40.328  -48.817 1.00 27.75  ? 95   PHE F CG    1 
ATOM   17132 C CD1   . PHE F 1 95  ? -43.668  -39.396  -49.303 1.00 22.14  ? 95   PHE F CD1   1 
ATOM   17133 C CD2   . PHE F 1 95  ? -45.970  -40.024  -48.876 1.00 22.66  ? 95   PHE F CD2   1 
ATOM   17134 C CE1   . PHE F 1 95  ? -44.122  -38.213  -49.892 1.00 24.37  ? 95   PHE F CE1   1 
ATOM   17135 C CE2   . PHE F 1 95  ? -46.411  -38.837  -49.443 1.00 21.10  ? 95   PHE F CE2   1 
ATOM   17136 C CZ    . PHE F 1 95  ? -45.493  -37.927  -49.935 1.00 25.48  ? 95   PHE F CZ    1 
ATOM   17137 N N     . ASP F 1 96  ? -42.457  -40.902  -44.915 1.00 26.28  ? 96   ASP F N     1 
ATOM   17138 C CA    . ASP F 1 96  ? -42.747  -40.551  -43.535 1.00 27.71  ? 96   ASP F CA    1 
ATOM   17139 C C     . ASP F 1 96  ? -41.665  -39.592  -43.039 1.00 27.57  ? 96   ASP F C     1 
ATOM   17140 O O     . ASP F 1 96  ? -40.668  -39.337  -43.709 1.00 26.34  ? 96   ASP F O     1 
ATOM   17141 C CB    . ASP F 1 96  ? -42.977  -41.786  -42.679 1.00 30.47  ? 96   ASP F CB    1 
ATOM   17142 C CG    . ASP F 1 96  ? -41.735  -42.560  -42.202 1.00 34.67  ? 96   ASP F CG    1 
ATOM   17143 O OD1   . ASP F 1 96  ? -40.594  -42.027  -42.348 1.00 36.29  ? 96   ASP F OD1   1 
ATOM   17144 O OD2   . ASP F 1 96  ? -41.903  -43.694  -41.654 1.00 35.53  ? 96   ASP F OD2   1 
ATOM   17145 N N     . VAL F 1 97  ? -41.866  -39.079  -41.831 1.00 28.74  ? 97   VAL F N     1 
ATOM   17146 C CA    . VAL F 1 97  ? -41.056  -37.975  -41.349 1.00 29.17  ? 97   VAL F CA    1 
ATOM   17147 C C     . VAL F 1 97  ? -39.621  -38.443  -41.070 1.00 32.29  ? 97   VAL F C     1 
ATOM   17148 O O     . VAL F 1 97  ? -38.704  -37.620  -41.096 1.00 31.75  ? 97   VAL F O     1 
ATOM   17149 C CB    . VAL F 1 97  ? -41.741  -37.399  -40.100 1.00 25.74  ? 97   VAL F CB    1 
ATOM   17150 C CG1   . VAL F 1 97  ? -41.767  -38.426  -38.970 1.00 24.31  ? 97   VAL F CG1   1 
ATOM   17151 C CG2   . VAL F 1 97  ? -41.068  -36.114  -39.663 1.00 26.99  ? 97   VAL F CG2   1 
ATOM   17152 N N     . MET F 1 98  ? -39.421  -39.756  -40.839 1.00 32.81  ? 98   MET F N     1 
ATOM   17153 C CA    . MET F 1 98  ? -38.069  -40.259  -40.623 1.00 33.41  ? 98   MET F CA    1 
ATOM   17154 C C     . MET F 1 98  ? -37.239  -40.200  -41.912 1.00 35.59  ? 98   MET F C     1 
ATOM   17155 O O     . MET F 1 98  ? -36.023  -40.221  -41.843 1.00 38.50  ? 98   MET F O     1 
ATOM   17156 C CB    . MET F 1 98  ? -38.036  -41.665  -40.017 1.00 28.23  ? 98   MET F CB    1 
ATOM   17157 C CG    . MET F 1 98  ? -38.806  -41.803  -38.723 1.00 32.42  ? 98   MET F CG    1 
ATOM   17158 S SD    . MET F 1 98  ? -38.436  -40.593  -37.431 1.00 43.79  ? 98   MET F SD    1 
ATOM   17159 C CE    . MET F 1 98  ? -36.730  -40.868  -36.928 1.00 40.90  ? 98   MET F CE    1 
ATOM   17160 N N     . HIS F 1 99  ? -37.881  -40.047  -43.074 1.00 30.67  ? 99   HIS F N     1 
ATOM   17161 C CA    . HIS F 1 99  ? -37.173  -39.931  -44.336 1.00 29.75  ? 99   HIS F CA    1 
ATOM   17162 C C     . HIS F 1 99  ? -37.158  -38.484  -44.799 1.00 31.43  ? 99   HIS F C     1 
ATOM   17163 O O     . HIS F 1 99  ? -36.846  -38.210  -45.961 1.00 32.35  ? 99   HIS F O     1 
ATOM   17164 C CB    . HIS F 1 99  ? -37.813  -40.835  -45.403 1.00 30.01  ? 99   HIS F CB    1 
ATOM   17165 C CG    . HIS F 1 99  ? -37.642  -42.271  -45.054 1.00 38.03  ? 99   HIS F CG    1 
ATOM   17166 N ND1   . HIS F 1 99  ? -38.395  -42.898  -44.073 1.00 42.19  ? 99   HIS F ND1   1 
ATOM   17167 C CD2   . HIS F 1 99  ? -36.772  -43.187  -45.509 1.00 37.92  ? 99   HIS F CD2   1 
ATOM   17168 C CE1   . HIS F 1 99  ? -38.011  -44.169  -43.969 1.00 39.89  ? 99   HIS F CE1   1 
ATOM   17169 N NE2   . HIS F 1 99  ? -37.040  -44.369  -44.846 1.00 39.54  ? 99   HIS F NE2   1 
ATOM   17170 N N     . ALA F 1 100 ? -37.534  -37.567  -43.901 1.00 31.45  ? 100  ALA F N     1 
ATOM   17171 C CA    . ALA F 1 100 ? -37.483  -36.147  -44.230 1.00 29.92  ? 100  ALA F CA    1 
ATOM   17172 C C     . ALA F 1 100 ? -36.342  -35.526  -43.430 1.00 28.37  ? 100  ALA F C     1 
ATOM   17173 O O     . ALA F 1 100 ? -35.939  -36.073  -42.400 1.00 27.95  ? 100  ALA F O     1 
ATOM   17174 C CB    . ALA F 1 100 ? -38.810  -35.522  -43.869 1.00 28.95  ? 100  ALA F CB    1 
ATOM   17175 N N     . PRO F 1 101 ? -35.807  -34.359  -43.831 1.00 27.93  ? 101  PRO F N     1 
ATOM   17176 C CA    . PRO F 1 101 ? -34.821  -33.664  -43.004 1.00 30.20  ? 101  PRO F CA    1 
ATOM   17177 C C     . PRO F 1 101 ? -35.202  -33.526  -41.529 1.00 33.44  ? 101  PRO F C     1 
ATOM   17178 O O     . PRO F 1 101 ? -34.341  -33.526  -40.671 1.00 38.07  ? 101  PRO F O     1 
ATOM   17179 C CB    . PRO F 1 101 ? -34.521  -32.330  -43.710 1.00 28.99  ? 101  PRO F CB    1 
ATOM   17180 C CG    . PRO F 1 101 ? -35.566  -32.273  -44.816 1.00 31.49  ? 101  PRO F CG    1 
ATOM   17181 C CD    . PRO F 1 101 ? -36.122  -33.654  -45.085 1.00 29.50  ? 101  PRO F CD    1 
ATOM   17182 N N     . ALA F 1 102 ? -36.490  -33.446  -41.207 1.00 32.81  ? 102  ALA F N     1 
ATOM   17183 C CA    . ALA F 1 102 ? -36.895  -33.318  -39.820 1.00 30.55  ? 102  ALA F CA    1 
ATOM   17184 C C     . ALA F 1 102 ? -36.286  -34.422  -38.950 1.00 32.67  ? 102  ALA F C     1 
ATOM   17185 O O     . ALA F 1 102 ? -35.860  -34.146  -37.831 1.00 29.88  ? 102  ALA F O     1 
ATOM   17186 C CB    . ALA F 1 102 ? -38.414  -33.300  -39.727 1.00 25.01  ? 102  ALA F CB    1 
ATOM   17187 N N     . ARG F 1 103 ? -36.359  -35.674  -39.427 1.00 34.21  ? 103  ARG F N     1 
ATOM   17188 C CA    . ARG F 1 103 ? -35.843  -36.854  -38.737 1.00 39.61  ? 103  ARG F CA    1 
ATOM   17189 C C     . ARG F 1 103 ? -36.268  -36.906  -37.271 1.00 39.56  ? 103  ARG F C     1 
ATOM   17190 O O     . ARG F 1 103 ? -35.454  -37.231  -36.419 1.00 46.40  ? 103  ARG F O     1 
ATOM   17191 C CB    . ARG F 1 103 ? -34.312  -36.938  -38.728 1.00 42.57  ? 103  ARG F CB    1 
ATOM   17192 C CG    . ARG F 1 103 ? -33.744  -37.385  -40.068 1.00 49.90  ? 103  ARG F CG    1 
ATOM   17193 C CD    . ARG F 1 103 ? -32.262  -37.348  -39.959 1.00 70.42  ? 103  ARG F CD    1 
ATOM   17194 N NE    . ARG F 1 103 ? -31.655  -38.213  -40.982 1.00 81.50  ? 103  ARG F NE    1 
ATOM   17195 C CZ    . ARG F 1 103 ? -31.017  -37.878  -42.099 1.00 83.53  ? 103  ARG F CZ    1 
ATOM   17196 N NH1   . ARG F 1 103 ? -30.929  -36.609  -42.485 1.00 98.99  ? 103  ARG F NH1   1 
ATOM   17197 N NH2   . ARG F 1 103 ? -30.494  -38.842  -42.841 1.00 78.95  ? 103  ARG F NH2   1 
ATOM   17198 N N     . ARG F 1 104 ? -37.531  -36.613  -36.981 1.00 38.75  ? 104  ARG F N     1 
ATOM   17199 C CA    . ARG F 1 104 ? -38.047  -36.675  -35.620 1.00 34.64  ? 104  ARG F CA    1 
ATOM   17200 C C     . ARG F 1 104 ? -39.443  -37.263  -35.707 1.00 30.78  ? 104  ARG F C     1 
ATOM   17201 O O     . ARG F 1 104 ? -40.193  -36.920  -36.633 1.00 33.77  ? 104  ARG F O     1 
ATOM   17202 C CB    . ARG F 1 104 ? -38.279  -35.264  -35.050 1.00 33.43  ? 104  ARG F CB    1 
ATOM   17203 C CG    . ARG F 1 104 ? -37.042  -34.425  -34.763 1.00 33.91  ? 104  ARG F CG    1 
ATOM   17204 C CD    . ARG F 1 104 ? -37.219  -32.938  -35.062 1.00 31.46  ? 104  ARG F CD    1 
ATOM   17205 N NE    . ARG F 1 104 ? -38.266  -32.324  -34.239 1.00 32.56  ? 104  ARG F NE    1 
ATOM   17206 C CZ    . ARG F 1 104 ? -38.742  -31.086  -34.450 1.00 36.74  ? 104  ARG F CZ    1 
ATOM   17207 N NH1   . ARG F 1 104 ? -38.216  -30.336  -35.422 1.00 31.89  ? 104  ARG F NH1   1 
ATOM   17208 N NH2   . ARG F 1 104 ? -39.746  -30.636  -33.693 1.00 29.60  ? 104  ARG F NH2   1 
ATOM   17209 N N     . ASP F 1 105 ? -39.800  -38.115  -34.740 1.00 27.61  ? 105  ASP F N     1 
ATOM   17210 C CA    . ASP F 1 105 ? -41.161  -38.613  -34.670 1.00 28.48  ? 105  ASP F CA    1 
ATOM   17211 C C     . ASP F 1 105 ? -42.043  -37.529  -34.035 1.00 34.19  ? 105  ASP F C     1 
ATOM   17212 O O     . ASP F 1 105 ? -42.050  -37.360  -32.812 1.00 36.34  ? 105  ASP F O     1 
ATOM   17213 C CB    . ASP F 1 105 ? -41.237  -39.973  -34.001 1.00 32.76  ? 105  ASP F CB    1 
ATOM   17214 C CG    . ASP F 1 105 ? -42.622  -40.597  -34.078 1.00 38.45  ? 105  ASP F CG    1 
ATOM   17215 O OD1   . ASP F 1 105 ? -43.593  -39.805  -34.033 1.00 38.78  ? 105  ASP F OD1   1 
ATOM   17216 O OD2   . ASP F 1 105 ? -42.731  -41.854  -34.166 1.00 39.16  ? 105  ASP F OD2   1 
ATOM   17217 N N     . LEU F 1 106 ? -42.803  -36.800  -34.878 1.00 34.72  ? 106  LEU F N     1 
ATOM   17218 C CA    . LEU F 1 106 ? -43.555  -35.633  -34.441 1.00 29.67  ? 106  LEU F CA    1 
ATOM   17219 C C     . LEU F 1 106 ? -44.740  -36.072  -33.589 1.00 29.47  ? 106  LEU F C     1 
ATOM   17220 O O     . LEU F 1 106 ? -45.116  -35.373  -32.650 1.00 32.48  ? 106  LEU F O     1 
ATOM   17221 C CB    . LEU F 1 106 ? -43.990  -34.821  -35.657 1.00 28.54  ? 106  LEU F CB    1 
ATOM   17222 C CG    . LEU F 1 106 ? -42.832  -34.353  -36.532 1.00 30.60  ? 106  LEU F CG    1 
ATOM   17223 C CD1   . LEU F 1 106 ? -43.324  -33.842  -37.875 1.00 24.45  ? 106  LEU F CD1   1 
ATOM   17224 C CD2   . LEU F 1 106 ? -42.006  -33.312  -35.765 1.00 26.20  ? 106  LEU F CD2   1 
ATOM   17225 N N     . ILE F 1 107 ? -45.309  -37.248  -33.892 1.00 24.07  ? 107  ILE F N     1 
ATOM   17226 C CA    . ILE F 1 107 ? -46.366  -37.783  -33.049 1.00 26.55  ? 107  ILE F CA    1 
ATOM   17227 C C     . ILE F 1 107 ? -45.857  -38.076  -31.629 1.00 31.50  ? 107  ILE F C     1 
ATOM   17228 O O     . ILE F 1 107 ? -46.584  -37.846  -30.663 1.00 35.14  ? 107  ILE F O     1 
ATOM   17229 C CB    . ILE F 1 107 ? -47.068  -38.970  -33.718 1.00 25.72  ? 107  ILE F CB    1 
ATOM   17230 C CG1   . ILE F 1 107 ? -47.663  -38.600  -35.110 1.00 25.87  ? 107  ILE F CG1   1 
ATOM   17231 C CG2   . ILE F 1 107 ? -48.110  -39.614  -32.803 1.00 24.43  ? 107  ILE F CG2   1 
ATOM   17232 C CD1   . ILE F 1 107 ? -48.244  -37.195  -35.225 1.00 27.81  ? 107  ILE F CD1   1 
ATOM   17233 N N     . ALA F 1 108 ? -44.601  -38.524  -31.484 1.00 34.64  ? 108  ALA F N     1 
ATOM   17234 C CA    . ALA F 1 108 ? -44.056  -38.788  -30.149 1.00 31.46  ? 108  ALA F CA    1 
ATOM   17235 C C     . ALA F 1 108 ? -43.921  -37.478  -29.394 1.00 31.12  ? 108  ALA F C     1 
ATOM   17236 O O     . ALA F 1 108 ? -44.301  -37.415  -28.218 1.00 33.46  ? 108  ALA F O     1 
ATOM   17237 C CB    . ALA F 1 108 ? -42.729  -39.553  -30.172 1.00 28.71  ? 108  ALA F CB    1 
ATOM   17238 N N     . GLU F 1 109 ? -43.429  -36.431  -30.086 1.00 26.35  ? 109  GLU F N     1 
ATOM   17239 C CA    . GLU F 1 109 ? -43.331  -35.113  -29.463 1.00 29.47  ? 109  GLU F CA    1 
ATOM   17240 C C     . GLU F 1 109 ? -44.716  -34.625  -29.026 1.00 33.20  ? 109  GLU F C     1 
ATOM   17241 O O     . GLU F 1 109 ? -44.870  -34.119  -27.918 1.00 35.62  ? 109  GLU F O     1 
ATOM   17242 C CB    . GLU F 1 109 ? -42.656  -34.116  -30.392 1.00 25.96  ? 109  GLU F CB    1 
ATOM   17243 C CG    . GLU F 1 109 ? -41.213  -34.495  -30.706 1.00 25.54  ? 109  GLU F CG    1 
ATOM   17244 C CD    . GLU F 1 109 ? -40.571  -33.472  -31.657 1.00 35.60  ? 109  GLU F CD    1 
ATOM   17245 O OE1   . GLU F 1 109 ? -41.219  -32.421  -31.973 1.00 36.85  ? 109  GLU F OE1   1 
ATOM   17246 O OE2   . GLU F 1 109 ? -39.419  -33.711  -32.104 1.00 35.55  ? 109  GLU F OE2   1 
ATOM   17247 N N     . PHE F 1 110 ? -45.729  -34.863  -29.874 1.00 29.25  ? 110  PHE F N     1 
ATOM   17248 C CA    . PHE F 1 110 ? -47.071  -34.367  -29.657 1.00 27.49  ? 110  PHE F CA    1 
ATOM   17249 C C     . PHE F 1 110 ? -47.689  -35.043  -28.440 1.00 30.11  ? 110  PHE F C     1 
ATOM   17250 O O     . PHE F 1 110 ? -48.292  -34.377  -27.601 1.00 28.00  ? 110  PHE F O     1 
ATOM   17251 C CB    . PHE F 1 110 ? -47.855  -34.624  -30.945 1.00 23.71  ? 110  PHE F CB    1 
ATOM   17252 C CG    . PHE F 1 110 ? -49.364  -34.493  -30.805 1.00 21.93  ? 110  PHE F CG    1 
ATOM   17253 C CD1   . PHE F 1 110 ? -49.961  -33.249  -30.569 1.00 23.49  ? 110  PHE F CD1   1 
ATOM   17254 C CD2   . PHE F 1 110 ? -50.186  -35.601  -30.953 1.00 21.87  ? 110  PHE F CD2   1 
ATOM   17255 C CE1   . PHE F 1 110 ? -51.346  -33.131  -30.471 1.00 21.96  ? 110  PHE F CE1   1 
ATOM   17256 C CE2   . PHE F 1 110 ? -51.583  -35.485  -30.867 1.00 25.49  ? 110  PHE F CE2   1 
ATOM   17257 C CZ    . PHE F 1 110 ? -52.164  -34.241  -30.618 1.00 25.95  ? 110  PHE F CZ    1 
ATOM   17258 N N     . VAL F 1 111 ? -47.553  -36.371  -28.357 1.00 28.23  ? 111  VAL F N     1 
ATOM   17259 C CA    . VAL F 1 111 ? -48.160  -37.119  -27.268 1.00 27.18  ? 111  VAL F CA    1 
ATOM   17260 C C     . VAL F 1 111 ? -47.557  -36.696  -25.918 1.00 29.93  ? 111  VAL F C     1 
ATOM   17261 O O     . VAL F 1 111 ? -48.268  -36.535  -24.931 1.00 30.16  ? 111  VAL F O     1 
ATOM   17262 C CB    . VAL F 1 111 ? -47.967  -38.620  -27.564 1.00 30.33  ? 111  VAL F CB    1 
ATOM   17263 C CG1   . VAL F 1 111 ? -48.030  -39.457  -26.300 1.00 35.77  ? 111  VAL F CG1   1 
ATOM   17264 C CG2   . VAL F 1 111 ? -48.991  -39.135  -28.568 1.00 30.29  ? 111  VAL F CG2   1 
ATOM   17265 N N     . ALA F 1 112 ? -46.234  -36.506  -25.866 1.00 32.93  ? 112  ALA F N     1 
ATOM   17266 C CA    . ALA F 1 112 ? -45.568  -36.116  -24.630 1.00 34.11  ? 112  ALA F CA    1 
ATOM   17267 C C     . ALA F 1 112 ? -46.030  -34.713  -24.216 1.00 37.62  ? 112  ALA F C     1 
ATOM   17268 O O     . ALA F 1 112 ? -46.349  -34.462  -23.047 1.00 37.66  ? 112  ALA F O     1 
ATOM   17269 C CB    . ALA F 1 112 ? -44.055  -36.226  -24.777 1.00 28.41  ? 112  ALA F CB    1 
ATOM   17270 N N     . ALA F 1 113 ? -46.125  -33.795  -25.198 1.00 34.26  ? 113  ALA F N     1 
ATOM   17271 C CA    . ALA F 1 113 ? -46.561  -32.433  -24.915 1.00 29.36  ? 113  ALA F CA    1 
ATOM   17272 C C     . ALA F 1 113 ? -48.002  -32.433  -24.388 1.00 29.03  ? 113  ALA F C     1 
ATOM   17273 O O     . ALA F 1 113 ? -48.296  -31.739  -23.430 1.00 31.55  ? 113  ALA F O     1 
ATOM   17274 C CB    . ALA F 1 113 ? -46.384  -31.569  -26.123 1.00 26.98  ? 113  ALA F CB    1 
ATOM   17275 N N     . CYS F 1 114 ? -48.875  -33.265  -24.962 1.00 27.53  ? 114  CYS F N     1 
ATOM   17276 C CA    . CYS F 1 114 ? -50.253  -33.340  -24.503 1.00 29.52  ? 114  CYS F CA    1 
ATOM   17277 C C     . CYS F 1 114 ? -50.315  -33.830  -23.058 1.00 30.53  ? 114  CYS F C     1 
ATOM   17278 O O     . CYS F 1 114 ? -51.074  -33.291  -22.268 1.00 31.77  ? 114  CYS F O     1 
ATOM   17279 C CB    . CYS F 1 114 ? -51.132  -34.255  -25.348 1.00 25.39  ? 114  CYS F CB    1 
ATOM   17280 S SG    . CYS F 1 114 ? -51.466  -33.545  -26.969 1.00 31.42  ? 114  CYS F SG    1 
ATOM   17281 N N     . ARG F 1 115 ? -49.519  -34.850  -22.737 1.00 33.63  ? 115  ARG F N     1 
ATOM   17282 C CA    . ARG F 1 115 ? -49.576  -35.453  -21.416 1.00 33.50  ? 115  ARG F CA    1 
ATOM   17283 C C     . ARG F 1 115 ? -49.129  -34.441  -20.370 1.00 34.12  ? 115  ARG F C     1 
ATOM   17284 O O     . ARG F 1 115 ? -49.734  -34.387  -19.308 1.00 33.60  ? 115  ARG F O     1 
ATOM   17285 C CB    . ARG F 1 115 ? -48.726  -36.717  -21.236 1.00 34.62  ? 115  ARG F CB    1 
ATOM   17286 C CG    . ARG F 1 115 ? -49.592  -37.839  -21.779 1.00 46.78  ? 115  ARG F CG    1 
ATOM   17287 C CD    . ARG F 1 115 ? -48.682  -39.017  -22.068 1.00 47.03  ? 115  ARG F CD    1 
ATOM   17288 N NE    . ARG F 1 115 ? -49.517  -39.956  -22.823 1.00 49.50  ? 115  ARG F NE    1 
ATOM   17289 C CZ    . ARG F 1 115 ? -49.031  -40.956  -23.522 1.00 52.96  ? 115  ARG F CZ    1 
ATOM   17290 N NH1   . ARG F 1 115 ? -47.703  -41.083  -23.560 1.00 47.46  ? 115  ARG F NH1   1 
ATOM   17291 N NH2   . ARG F 1 115 ? -49.849  -41.757  -24.193 1.00 53.50  ? 115  ARG F NH2   1 
ATOM   17292 N N     . GLU F 1 116 ? -48.096  -33.645  -20.676 1.00 31.60  ? 116  GLU F N     1 
ATOM   17293 C CA    . GLU F 1 116 ? -47.641  -32.686  -19.697 1.00 39.01  ? 116  GLU F CA    1 
ATOM   17294 C C     . GLU F 1 116 ? -48.700  -31.624  -19.423 1.00 38.52  ? 116  GLU F C     1 
ATOM   17295 O O     . GLU F 1 116 ? -48.665  -31.038  -18.349 1.00 39.68  ? 116  GLU F O     1 
ATOM   17296 C CB    . GLU F 1 116 ? -46.185  -32.251  -19.838 1.00 51.73  ? 116  GLU F CB    1 
ATOM   17297 C CG    . GLU F 1 116 ? -45.892  -31.262  -20.954 1.00 83.72  ? 116  GLU F CG    1 
ATOM   17298 C CD    . GLU F 1 116 ? -44.410  -31.349  -21.320 1.00 103.11 ? 116  GLU F CD    1 
ATOM   17299 O OE1   . GLU F 1 116 ? -43.770  -32.294  -20.807 1.00 106.53 ? 116  GLU F OE1   1 
ATOM   17300 O OE2   . GLU F 1 116 ? -43.886  -30.517  -22.097 1.00 87.53  ? 116  GLU F OE2   1 
ATOM   17301 N N     . GLU F 1 117 ? -49.646  -31.400  -20.354 1.00 38.39  ? 117  GLU F N     1 
ATOM   17302 C CA    . GLU F 1 117 ? -50.634  -30.341  -20.193 1.00 38.22  ? 117  GLU F CA    1 
ATOM   17303 C C     . GLU F 1 117 ? -51.986  -30.926  -19.823 1.00 35.48  ? 117  GLU F C     1 
ATOM   17304 O O     . GLU F 1 117 ? -52.970  -30.192  -19.784 1.00 35.02  ? 117  GLU F O     1 
ATOM   17305 C CB    . GLU F 1 117 ? -50.761  -29.467  -21.440 1.00 39.03  ? 117  GLU F CB    1 
ATOM   17306 C CG    . GLU F 1 117 ? -49.525  -28.604  -21.703 1.00 41.12  ? 117  GLU F CG    1 
ATOM   17307 C CD    . GLU F 1 117 ? -49.364  -27.339  -20.850 1.00 51.85  ? 117  GLU F CD    1 
ATOM   17308 O OE1   . GLU F 1 117 ? -50.079  -27.159  -19.830 1.00 52.47  ? 117  GLU F OE1   1 
ATOM   17309 O OE2   . GLU F 1 117 ? -48.554  -26.474  -21.263 1.00 64.93  ? 117  GLU F OE2   1 
ATOM   17310 N N     . ASP F 1 118 ? -52.035  -32.248  -19.580 1.00 32.06  ? 118  ASP F N     1 
ATOM   17311 C CA    . ASP F 1 118 ? -53.293  -32.924  -19.264 1.00 33.40  ? 118  ASP F CA    1 
ATOM   17312 C C     . ASP F 1 118 ? -54.300  -32.793  -20.421 1.00 36.78  ? 118  ASP F C     1 
ATOM   17313 O O     . ASP F 1 118 ? -55.513  -32.716  -20.217 1.00 34.11  ? 118  ASP F O     1 
ATOM   17314 C CB    . ASP F 1 118 ? -53.836  -32.539  -17.884 1.00 36.48  ? 118  ASP F CB    1 
ATOM   17315 C CG    . ASP F 1 118 ? -52.951  -32.941  -16.704 1.00 47.15  ? 118  ASP F CG    1 
ATOM   17316 O OD1   . ASP F 1 118 ? -52.527  -34.104  -16.696 1.00 48.69  ? 118  ASP F OD1   1 
ATOM   17317 O OD2   . ASP F 1 118 ? -52.660  -32.098  -15.805 1.00 60.03  ? 118  ASP F OD2   1 
ATOM   17318 N N     . LEU F 1 119 ? -53.816  -32.841  -21.671 1.00 31.77  ? 119  LEU F N     1 
ATOM   17319 C CA    . LEU F 1 119 ? -54.697  -32.874  -22.820 1.00 28.46  ? 119  LEU F CA    1 
ATOM   17320 C C     . LEU F 1 119 ? -54.740  -34.291  -23.366 1.00 27.81  ? 119  LEU F C     1 
ATOM   17321 O O     . LEU F 1 119 ? -53.717  -34.965  -23.375 1.00 33.96  ? 119  LEU F O     1 
ATOM   17322 C CB    . LEU F 1 119 ? -54.127  -31.925  -23.870 1.00 28.15  ? 119  LEU F CB    1 
ATOM   17323 C CG    . LEU F 1 119 ? -53.948  -30.474  -23.422 1.00 29.25  ? 119  LEU F CG    1 
ATOM   17324 C CD1   . LEU F 1 119 ? -53.317  -29.637  -24.514 1.00 30.10  ? 119  LEU F CD1   1 
ATOM   17325 C CD2   . LEU F 1 119 ? -55.290  -29.858  -23.027 1.00 27.29  ? 119  LEU F CD2   1 
ATOM   17326 N N     . LEU F 1 120 ? -55.901  -34.724  -23.877 1.00 25.75  ? 120  LEU F N     1 
ATOM   17327 C CA    . LEU F 1 120 ? -55.927  -35.977  -24.609 1.00 28.48  ? 120  LEU F CA    1 
ATOM   17328 C C     . LEU F 1 120 ? -55.377  -35.808  -26.027 1.00 32.66  ? 120  LEU F C     1 
ATOM   17329 O O     . LEU F 1 120 ? -55.840  -34.940  -26.763 1.00 33.73  ? 120  LEU F O     1 
ATOM   17330 C CB    . LEU F 1 120 ? -57.325  -36.586  -24.591 1.00 28.57  ? 120  LEU F CB    1 
ATOM   17331 C CG    . LEU F 1 120 ? -57.797  -37.051  -23.205 1.00 31.15  ? 120  LEU F CG    1 
ATOM   17332 C CD1   . LEU F 1 120 ? -59.138  -37.703  -23.353 1.00 28.32  ? 120  LEU F CD1   1 
ATOM   17333 C CD2   . LEU F 1 120 ? -56.796  -37.981  -22.482 1.00 28.51  ? 120  LEU F CD2   1 
ATOM   17334 N N     . PRO F 1 121 ? -54.398  -36.645  -26.465 1.00 30.87  ? 121  PRO F N     1 
ATOM   17335 C CA    . PRO F 1 121 ? -53.956  -36.642  -27.857 1.00 28.06  ? 121  PRO F CA    1 
ATOM   17336 C C     . PRO F 1 121 ? -54.846  -37.497  -28.749 1.00 26.59  ? 121  PRO F C     1 
ATOM   17337 O O     . PRO F 1 121 ? -55.152  -38.638  -28.411 1.00 30.43  ? 121  PRO F O     1 
ATOM   17338 C CB    . PRO F 1 121 ? -52.524  -37.209  -27.782 1.00 30.00  ? 121  PRO F CB    1 
ATOM   17339 C CG    . PRO F 1 121 ? -52.675  -38.202  -26.624 1.00 27.95  ? 121  PRO F CG    1 
ATOM   17340 C CD    . PRO F 1 121 ? -53.644  -37.603  -25.634 1.00 27.60  ? 121  PRO F CD    1 
ATOM   17341 N N     . PHE F 1 122 ? -55.312  -36.922  -29.857 1.00 25.17  ? 122  PHE F N     1 
ATOM   17342 C CA    . PHE F 1 122 ? -56.143  -37.664  -30.792 1.00 24.15  ? 122  PHE F CA    1 
ATOM   17343 C C     . PHE F 1 122 ? -55.428  -37.683  -32.133 1.00 24.31  ? 122  PHE F C     1 
ATOM   17344 O O     . PHE F 1 122 ? -54.794  -36.688  -32.510 1.00 23.45  ? 122  PHE F O     1 
ATOM   17345 C CB    . PHE F 1 122 ? -57.518  -37.032  -31.038 1.00 24.21  ? 122  PHE F CB    1 
ATOM   17346 C CG    . PHE F 1 122 ? -58.603  -37.338  -30.022 1.00 24.79  ? 122  PHE F CG    1 
ATOM   17347 C CD1   . PHE F 1 122 ? -58.401  -37.133  -28.656 1.00 22.63  ? 122  PHE F CD1   1 
ATOM   17348 C CD2   . PHE F 1 122 ? -59.829  -37.843  -30.447 1.00 25.71  ? 122  PHE F CD2   1 
ATOM   17349 C CE1   . PHE F 1 122 ? -59.418  -37.420  -27.755 1.00 21.85  ? 122  PHE F CE1   1 
ATOM   17350 C CE2   . PHE F 1 122 ? -60.836  -38.132  -29.533 1.00 23.19  ? 122  PHE F CE2   1 
ATOM   17351 C CZ    . PHE F 1 122 ? -60.632  -37.907  -28.192 1.00 22.20  ? 122  PHE F CZ    1 
ATOM   17352 N N     . PHE F 1 123 ? -55.563  -38.798  -32.849 1.00 22.19  ? 123  PHE F N     1 
ATOM   17353 C CA    . PHE F 1 123 ? -54.862  -38.968  -34.105 1.00 23.69  ? 123  PHE F CA    1 
ATOM   17354 C C     . PHE F 1 123 ? -55.859  -38.980  -35.250 1.00 23.51  ? 123  PHE F C     1 
ATOM   17355 O O     . PHE F 1 123 ? -56.704  -39.876  -35.342 1.00 25.90  ? 123  PHE F O     1 
ATOM   17356 C CB    . PHE F 1 123 ? -54.135  -40.317  -34.090 1.00 26.61  ? 123  PHE F CB    1 
ATOM   17357 C CG    . PHE F 1 123 ? -53.040  -40.458  -33.038 1.00 26.87  ? 123  PHE F CG    1 
ATOM   17358 C CD1   . PHE F 1 123 ? -52.327  -39.347  -32.568 1.00 23.40  ? 123  PHE F CD1   1 
ATOM   17359 C CD2   . PHE F 1 123 ? -52.723  -41.717  -32.533 1.00 24.97  ? 123  PHE F CD2   1 
ATOM   17360 C CE1   . PHE F 1 123 ? -51.327  -39.505  -31.605 1.00 24.59  ? 123  PHE F CE1   1 
ATOM   17361 C CE2   . PHE F 1 123 ? -51.703  -41.866  -31.584 1.00 26.12  ? 123  PHE F CE2   1 
ATOM   17362 C CZ    . PHE F 1 123 ? -51.014  -40.765  -31.107 1.00 23.91  ? 123  PHE F CZ    1 
ATOM   17363 N N     . TYR F 1 124 ? -55.766  -37.969  -36.121 1.00 22.41  ? 124  TYR F N     1 
ATOM   17364 C CA    . TYR F 1 124 ? -56.550  -37.989  -37.338 1.00 22.95  ? 124  TYR F CA    1 
ATOM   17365 C C     . TYR F 1 124 ? -55.815  -38.903  -38.320 1.00 25.05  ? 124  TYR F C     1 
ATOM   17366 O O     . TYR F 1 124 ? -54.585  -38.822  -38.460 1.00 25.73  ? 124  TYR F O     1 
ATOM   17367 C CB    . TYR F 1 124 ? -56.652  -36.546  -37.876 1.00 22.03  ? 124  TYR F CB    1 
ATOM   17368 C CG    . TYR F 1 124 ? -57.134  -36.437  -39.317 1.00 22.85  ? 124  TYR F CG    1 
ATOM   17369 C CD1   . TYR F 1 124 ? -56.310  -36.826  -40.376 1.00 23.46  ? 124  TYR F CD1   1 
ATOM   17370 C CD2   . TYR F 1 124 ? -58.420  -35.971  -39.625 1.00 23.63  ? 124  TYR F CD2   1 
ATOM   17371 C CE1   . TYR F 1 124 ? -56.738  -36.741  -41.690 1.00 24.29  ? 124  TYR F CE1   1 
ATOM   17372 C CE2   . TYR F 1 124 ? -58.858  -35.881  -40.937 1.00 25.89  ? 124  TYR F CE2   1 
ATOM   17373 C CZ    . TYR F 1 124 ? -58.016  -36.275  -41.968 1.00 27.22  ? 124  TYR F CZ    1 
ATOM   17374 O OH    . TYR F 1 124 ? -58.423  -36.220  -43.283 1.00 30.77  ? 124  TYR F OH    1 
ATOM   17375 N N     . MET F 1 125 ? -56.589  -39.733  -39.036 1.00 28.03  ? 125  MET F N     1 
ATOM   17376 C CA    . MET F 1 125 ? -56.021  -40.603  -40.055 1.00 25.67  ? 125  MET F CA    1 
ATOM   17377 C C     . MET F 1 125 ? -56.942  -40.592  -41.273 1.00 25.43  ? 125  MET F C     1 
ATOM   17378 O O     . MET F 1 125 ? -58.135  -40.880  -41.147 1.00 29.80  ? 125  MET F O     1 
ATOM   17379 C CB    . MET F 1 125 ? -55.842  -42.029  -39.508 1.00 28.41  ? 125  MET F CB    1 
ATOM   17380 C CG    . MET F 1 125 ? -55.582  -43.089  -40.581 1.00 28.64  ? 125  MET F CG    1 
ATOM   17381 S SD    . MET F 1 125 ? -53.975  -42.924  -41.399 1.00 30.05  ? 125  MET F SD    1 
ATOM   17382 C CE    . MET F 1 125 ? -52.824  -43.191  -40.036 1.00 20.44  ? 125  MET F CE    1 
ATOM   17383 N N     . ALA F 1 126 ? -56.399  -40.223  -42.441 1.00 20.83  ? 126  ALA F N     1 
ATOM   17384 C CA    . ALA F 1 126 ? -57.192  -40.263  -43.663 1.00 23.96  ? 126  ALA F CA    1 
ATOM   17385 C C     . ALA F 1 126 ? -57.261  -41.694  -44.203 1.00 26.43  ? 126  ALA F C     1 
ATOM   17386 O O     . ALA F 1 126 ? -56.240  -42.362  -44.341 1.00 28.67  ? 126  ALA F O     1 
ATOM   17387 C CB    . ALA F 1 126 ? -56.594  -39.337  -44.710 1.00 22.16  ? 126  ALA F CB    1 
ATOM   17388 N N     . THR F 1 127 ? -58.458  -42.169  -44.528 1.00 25.00  ? 127  THR F N     1 
ATOM   17389 C CA    . THR F 1 127 ? -58.575  -43.522  -45.056 1.00 24.32  ? 127  THR F CA    1 
ATOM   17390 C C     . THR F 1 127 ? -58.605  -43.502  -46.577 1.00 24.42  ? 127  THR F C     1 
ATOM   17391 O O     . THR F 1 127 ? -58.364  -44.520  -47.216 1.00 32.44  ? 127  THR F O     1 
ATOM   17392 C CB    . THR F 1 127 ? -59.785  -44.236  -44.458 1.00 24.56  ? 127  THR F CB    1 
ATOM   17393 O OG1   . THR F 1 127 ? -60.904  -43.524  -44.979 1.00 27.56  ? 127  THR F OG1   1 
ATOM   17394 C CG2   . THR F 1 127 ? -59.763  -44.223  -42.944 1.00 19.10  ? 127  THR F CG2   1 
ATOM   17395 N N     . TYR F 1 128 ? -58.878  -42.336  -47.166 1.00 27.60  ? 128  TYR F N     1 
ATOM   17396 C CA    . TYR F 1 128 ? -58.718  -42.165  -48.604 1.00 29.87  ? 128  TYR F CA    1 
ATOM   17397 C C     . TYR F 1 128 ? -57.303  -41.635  -48.844 1.00 33.49  ? 128  TYR F C     1 
ATOM   17398 O O     . TYR F 1 128 ? -56.963  -40.548  -48.363 1.00 30.22  ? 128  TYR F O     1 
ATOM   17399 C CB    . TYR F 1 128 ? -59.782  -41.131  -48.989 1.00 25.37  ? 128  TYR F CB    1 
ATOM   17400 C CG    . TYR F 1 128 ? -59.776  -40.612  -50.420 1.00 23.73  ? 128  TYR F CG    1 
ATOM   17401 C CD1   . TYR F 1 128 ? -59.310  -41.379  -51.492 1.00 21.63  ? 128  TYR F CD1   1 
ATOM   17402 C CD2   . TYR F 1 128 ? -60.263  -39.339  -50.705 1.00 23.97  ? 128  TYR F CD2   1 
ATOM   17403 C CE1   . TYR F 1 128 ? -59.361  -40.898  -52.795 1.00 22.65  ? 128  TYR F CE1   1 
ATOM   17404 C CE2   . TYR F 1 128 ? -60.333  -38.856  -52.006 1.00 23.04  ? 128  TYR F CE2   1 
ATOM   17405 C CZ    . TYR F 1 128 ? -59.871  -39.635  -53.053 1.00 23.99  ? 128  TYR F CZ    1 
ATOM   17406 O OH    . TYR F 1 128 ? -59.918  -39.161  -54.334 1.00 26.63  ? 128  TYR F OH    1 
ATOM   17407 N N     . ASP F 1 129 ? -56.496  -42.410  -49.589 1.00 31.21  ? 129  ASP F N     1 
ATOM   17408 C CA    . ASP F 1 129 ? -55.062  -42.180  -49.657 1.00 26.49  ? 129  ASP F CA    1 
ATOM   17409 C C     . ASP F 1 129 ? -54.637  -42.014  -51.113 1.00 25.99  ? 129  ASP F C     1 
ATOM   17410 O O     . ASP F 1 129 ? -54.962  -42.860  -51.929 1.00 27.03  ? 129  ASP F O     1 
ATOM   17411 C CB    . ASP F 1 129 ? -54.352  -43.325  -48.947 1.00 25.39  ? 129  ASP F CB    1 
ATOM   17412 C CG    . ASP F 1 129 ? -52.848  -43.174  -48.785 1.00 27.77  ? 129  ASP F CG    1 
ATOM   17413 O OD1   . ASP F 1 129 ? -52.162  -42.865  -49.811 1.00 28.23  ? 129  ASP F OD1   1 
ATOM   17414 O OD2   . ASP F 1 129 ? -52.368  -43.391  -47.648 1.00 24.12  ? 129  ASP F OD2   1 
ATOM   17415 N N     . TRP F 1 130 ? -53.921  -40.931  -51.440 1.00 29.41  ? 130  TRP F N     1 
ATOM   17416 C CA    . TRP F 1 130 ? -53.515  -40.626  -52.812 1.00 27.25  ? 130  TRP F CA    1 
ATOM   17417 C C     . TRP F 1 130 ? -52.093  -41.120  -53.062 1.00 30.75  ? 130  TRP F C     1 
ATOM   17418 O O     . TRP F 1 130 ? -51.595  -40.952  -54.180 1.00 26.40  ? 130  TRP F O     1 
ATOM   17419 C CB    . TRP F 1 130 ? -53.531  -39.107  -53.097 1.00 25.48  ? 130  TRP F CB    1 
ATOM   17420 C CG    . TRP F 1 130 ? -54.868  -38.445  -52.866 1.00 34.76  ? 130  TRP F CG    1 
ATOM   17421 C CD1   . TRP F 1 130 ? -56.091  -39.043  -52.946 1.00 34.15  ? 130  TRP F CD1   1 
ATOM   17422 C CD2   . TRP F 1 130 ? -55.120  -37.069  -52.487 1.00 28.88  ? 130  TRP F CD2   1 
ATOM   17423 N NE1   . TRP F 1 130 ? -57.076  -38.142  -52.641 1.00 34.39  ? 130  TRP F NE1   1 
ATOM   17424 C CE2   . TRP F 1 130 ? -56.516  -36.922  -52.365 1.00 29.43  ? 130  TRP F CE2   1 
ATOM   17425 C CE3   . TRP F 1 130 ? -54.306  -35.948  -52.261 1.00 27.90  ? 130  TRP F CE3   1 
ATOM   17426 C CZ2   . TRP F 1 130 ? -57.120  -35.706  -52.011 1.00 27.41  ? 130  TRP F CZ2   1 
ATOM   17427 C CZ3   . TRP F 1 130 ? -54.896  -34.750  -51.918 1.00 28.36  ? 130  TRP F CZ3   1 
ATOM   17428 C CH2   . TRP F 1 130 ? -56.285  -34.633  -51.781 1.00 26.06  ? 130  TRP F CH2   1 
ATOM   17429 N N     . HIS F 1 131 ? -51.385  -41.576  -52.002 1.00 27.43  ? 131  HIS F N     1 
ATOM   17430 C CA    . HIS F 1 131 ? -49.985  -41.900  -52.178 1.00 28.05  ? 131  HIS F CA    1 
ATOM   17431 C C     . HIS F 1 131 ? -49.781  -43.344  -52.647 1.00 28.74  ? 131  HIS F C     1 
ATOM   17432 O O     . HIS F 1 131 ? -49.085  -43.567  -53.633 1.00 31.96  ? 131  HIS F O     1 
ATOM   17433 C CB    . HIS F 1 131 ? -49.206  -41.714  -50.885 1.00 25.72  ? 131  HIS F CB    1 
ATOM   17434 C CG    . HIS F 1 131 ? -47.792  -42.189  -51.011 1.00 25.91  ? 131  HIS F CG    1 
ATOM   17435 N ND1   . HIS F 1 131 ? -46.883  -41.580  -51.862 1.00 23.61  ? 131  HIS F ND1   1 
ATOM   17436 C CD2   . HIS F 1 131 ? -47.133  -43.183  -50.387 1.00 23.79  ? 131  HIS F CD2   1 
ATOM   17437 C CE1   . HIS F 1 131 ? -45.707  -42.182  -51.742 1.00 23.71  ? 131  HIS F CE1   1 
ATOM   17438 N NE2   . HIS F 1 131 ? -45.832  -43.156  -50.849 1.00 26.91  ? 131  HIS F NE2   1 
ATOM   17439 N N     . THR F 1 132 ? -50.338  -44.323  -51.917 1.00 25.28  ? 132  THR F N     1 
ATOM   17440 C CA    . THR F 1 132 ? -50.082  -45.721  -52.201 1.00 29.94  ? 132  THR F CA    1 
ATOM   17441 C C     . THR F 1 132 ? -50.927  -46.193  -53.382 1.00 31.34  ? 132  THR F C     1 
ATOM   17442 O O     . THR F 1 132 ? -52.156  -46.055  -53.373 1.00 29.92  ? 132  THR F O     1 
ATOM   17443 C CB    . THR F 1 132 ? -50.314  -46.605  -50.974 1.00 33.25  ? 132  THR F CB    1 
ATOM   17444 O OG1   . THR F 1 132 ? -50.325  -47.949  -51.466 1.00 29.84  ? 132  THR F OG1   1 
ATOM   17445 C CG2   . THR F 1 132 ? -51.660  -46.334  -50.341 1.00 34.13  ? 132  THR F CG2   1 
ATOM   17446 N N     . PRO F 1 133 ? -50.299  -46.805  -54.418 1.00 32.85  ? 133  PRO F N     1 
ATOM   17447 C CA    . PRO F 1 133 ? -51.073  -47.358  -55.536 1.00 27.05  ? 133  PRO F CA    1 
ATOM   17448 C C     . PRO F 1 133 ? -52.026  -48.473  -55.098 1.00 26.28  ? 133  PRO F C     1 
ATOM   17449 O O     . PRO F 1 133 ? -52.976  -48.787  -55.803 1.00 25.79  ? 133  PRO F O     1 
ATOM   17450 C CB    . PRO F 1 133 ? -50.013  -47.814  -56.545 1.00 27.49  ? 133  PRO F CB    1 
ATOM   17451 C CG    . PRO F 1 133 ? -48.704  -47.926  -55.728 1.00 31.57  ? 133  PRO F CG    1 
ATOM   17452 C CD    . PRO F 1 133 ? -48.837  -46.993  -54.530 1.00 29.72  ? 133  PRO F CD    1 
ATOM   17453 N N     . LEU F 1 134 ? -51.806  -49.041  -53.895 1.00 24.78  ? 134  LEU F N     1 
ATOM   17454 C CA    . LEU F 1 134 ? -52.678  -50.098  -53.420 1.00 26.04  ? 134  LEU F CA    1 
ATOM   17455 C C     . LEU F 1 134 ? -54.122  -49.601  -53.392 1.00 32.90  ? 134  LEU F C     1 
ATOM   17456 O O     . LEU F 1 134 ? -55.037  -50.395  -53.597 1.00 34.35  ? 134  LEU F O     1 
ATOM   17457 C CB    . LEU F 1 134 ? -52.255  -50.664  -52.066 1.00 23.65  ? 134  LEU F CB    1 
ATOM   17458 C CG    . LEU F 1 134 ? -50.835  -51.245  -52.002 1.00 25.91  ? 134  LEU F CG    1 
ATOM   17459 C CD1   . LEU F 1 134 ? -50.504  -51.638  -50.553 1.00 22.42  ? 134  LEU F CD1   1 
ATOM   17460 C CD2   . LEU F 1 134 ? -50.660  -52.450  -53.000 1.00 22.69  ? 134  LEU F CD2   1 
ATOM   17461 N N     . TYR F 1 135 ? -54.343  -48.303  -53.133 1.00 32.39  ? 135  TYR F N     1 
ATOM   17462 C CA    . TYR F 1 135 ? -55.698  -47.810  -52.929 1.00 31.23  ? 135  TYR F CA    1 
ATOM   17463 C C     . TYR F 1 135 ? -56.594  -48.139  -54.135 1.00 28.73  ? 135  TYR F C     1 
ATOM   17464 O O     . TYR F 1 135 ? -57.703  -48.612  -53.966 1.00 31.24  ? 135  TYR F O     1 
ATOM   17465 C CB    . TYR F 1 135 ? -55.676  -46.322  -52.565 1.00 30.70  ? 135  TYR F CB    1 
ATOM   17466 C CG    . TYR F 1 135 ? -57.050  -45.804  -52.189 1.00 27.39  ? 135  TYR F CG    1 
ATOM   17467 C CD1   . TYR F 1 135 ? -57.515  -45.934  -50.881 1.00 26.38  ? 135  TYR F CD1   1 
ATOM   17468 C CD2   . TYR F 1 135 ? -57.883  -45.202  -53.143 1.00 27.26  ? 135  TYR F CD2   1 
ATOM   17469 C CE1   . TYR F 1 135 ? -58.764  -45.469  -50.517 1.00 27.89  ? 135  TYR F CE1   1 
ATOM   17470 C CE2   . TYR F 1 135 ? -59.132  -44.722  -52.792 1.00 28.86  ? 135  TYR F CE2   1 
ATOM   17471 C CZ    . TYR F 1 135 ? -59.564  -44.863  -51.476 1.00 28.92  ? 135  TYR F CZ    1 
ATOM   17472 O OH    . TYR F 1 135 ? -60.802  -44.433  -51.092 1.00 39.20  ? 135  TYR F OH    1 
ATOM   17473 N N     . ASP F 1 136 ? -56.135  -47.883  -55.353 1.00 28.88  ? 136  ASP F N     1 
ATOM   17474 C CA    . ASP F 1 136 ? -56.922  -48.189  -56.542 1.00 41.01  ? 136  ASP F CA    1 
ATOM   17475 C C     . ASP F 1 136 ? -56.626  -49.576  -57.124 1.00 42.12  ? 136  ASP F C     1 
ATOM   17476 O O     . ASP F 1 136 ? -57.507  -50.169  -57.728 1.00 43.85  ? 136  ASP F O     1 
ATOM   17477 C CB    . ASP F 1 136 ? -56.734  -47.155  -57.645 1.00 45.88  ? 136  ASP F CB    1 
ATOM   17478 C CG    . ASP F 1 136 ? -57.317  -45.778  -57.343 1.00 50.92  ? 136  ASP F CG    1 
ATOM   17479 O OD1   . ASP F 1 136 ? -58.424  -45.676  -56.725 1.00 52.71  ? 136  ASP F OD1   1 
ATOM   17480 O OD2   . ASP F 1 136 ? -56.658  -44.818  -57.741 1.00 52.48  ? 136  ASP F OD2   1 
ATOM   17481 N N     . ASP F 1 137 ? -55.397  -50.088  -56.953 1.00 39.73  ? 137  ASP F N     1 
ATOM   17482 C CA    . ASP F 1 137 ? -54.904  -51.263  -57.668 1.00 35.61  ? 137  ASP F CA    1 
ATOM   17483 C C     . ASP F 1 137 ? -55.154  -52.560  -56.901 1.00 38.92  ? 137  ASP F C     1 
ATOM   17484 O O     . ASP F 1 137 ? -55.171  -53.613  -57.519 1.00 45.44  ? 137  ASP F O     1 
ATOM   17485 C CB    . ASP F 1 137 ? -53.418  -51.183  -57.976 1.00 31.51  ? 137  ASP F CB    1 
ATOM   17486 C CG    . ASP F 1 137 ? -53.047  -50.161  -59.040 1.00 37.57  ? 137  ASP F CG    1 
ATOM   17487 O OD1   . ASP F 1 137 ? -53.979  -49.631  -59.697 1.00 42.60  ? 137  ASP F OD1   1 
ATOM   17488 O OD2   . ASP F 1 137 ? -51.836  -49.890  -59.223 1.00 41.84  ? 137  ASP F OD2   1 
ATOM   17489 N N     . ASP F 1 138 ? -55.359  -52.490  -55.576 1.00 37.95  ? 138  ASP F N     1 
ATOM   17490 C CA    . ASP F 1 138 ? -55.471  -53.678  -54.743 1.00 32.67  ? 138  ASP F CA    1 
ATOM   17491 C C     . ASP F 1 138 ? -56.062  -53.299  -53.382 1.00 36.92  ? 138  ASP F C     1 
ATOM   17492 O O     . ASP F 1 138 ? -55.382  -53.290  -52.340 1.00 36.06  ? 138  ASP F O     1 
ATOM   17493 C CB    . ASP F 1 138 ? -54.121  -54.371  -54.644 1.00 35.91  ? 138  ASP F CB    1 
ATOM   17494 C CG    . ASP F 1 138 ? -54.096  -55.742  -53.993 1.00 40.95  ? 138  ASP F CG    1 
ATOM   17495 O OD1   . ASP F 1 138 ? -55.169  -56.218  -53.556 1.00 41.82  ? 138  ASP F OD1   1 
ATOM   17496 O OD2   . ASP F 1 138 ? -52.978  -56.306  -53.902 1.00 45.65  ? 138  ASP F OD2   1 
ATOM   17497 N N     . PHE F 1 139 ? -57.368  -53.031  -53.401 1.00 39.11  ? 139  PHE F N     1 
ATOM   17498 C CA    . PHE F 1 139 ? -58.044  -52.462  -52.245 1.00 35.55  ? 139  PHE F CA    1 
ATOM   17499 C C     . PHE F 1 139 ? -57.847  -53.340  -51.012 1.00 33.27  ? 139  PHE F C     1 
ATOM   17500 O O     . PHE F 1 139 ? -57.535  -52.819  -49.940 1.00 37.76  ? 139  PHE F O     1 
ATOM   17501 C CB    . PHE F 1 139 ? -59.492  -52.071  -52.570 1.00 32.61  ? 139  PHE F CB    1 
ATOM   17502 C CG    . PHE F 1 139 ? -60.131  -51.265  -51.449 1.00 33.61  ? 139  PHE F CG    1 
ATOM   17503 C CD1   . PHE F 1 139 ? -59.746  -49.940  -51.219 1.00 32.83  ? 139  PHE F CD1   1 
ATOM   17504 C CD2   . PHE F 1 139 ? -61.121  -51.816  -50.642 1.00 34.01  ? 139  PHE F CD2   1 
ATOM   17505 C CE1   . PHE F 1 139 ? -60.317  -49.198  -50.174 1.00 35.88  ? 139  PHE F CE1   1 
ATOM   17506 C CE2   . PHE F 1 139 ? -61.723  -51.062  -49.629 1.00 37.17  ? 139  PHE F CE2   1 
ATOM   17507 C CZ    . PHE F 1 139 ? -61.307  -49.759  -49.377 1.00 33.15  ? 139  PHE F CZ    1 
ATOM   17508 N N     . PRO F 1 140 ? -58.009  -54.685  -51.099 1.00 39.55  ? 140  PRO F N     1 
ATOM   17509 C CA    . PRO F 1 140 ? -57.786  -55.545  -49.932 1.00 35.84  ? 140  PRO F CA    1 
ATOM   17510 C C     . PRO F 1 140 ? -56.414  -55.341  -49.290 1.00 33.57  ? 140  PRO F C     1 
ATOM   17511 O O     . PRO F 1 140 ? -56.297  -55.313  -48.071 1.00 33.11  ? 140  PRO F O     1 
ATOM   17512 C CB    . PRO F 1 140 ? -58.047  -56.984  -50.446 1.00 36.52  ? 140  PRO F CB    1 
ATOM   17513 C CG    . PRO F 1 140 ? -58.846  -56.765  -51.751 1.00 39.60  ? 140  PRO F CG    1 
ATOM   17514 C CD    . PRO F 1 140 ? -58.443  -55.442  -52.300 1.00 39.94  ? 140  PRO F CD    1 
ATOM   17515 N N     . ALA F 1 141 ? -55.379  -55.177  -50.119 1.00 28.22  ? 141  ALA F N     1 
ATOM   17516 C CA    . ALA F 1 141 ? -54.035  -54.965  -49.601 1.00 30.67  ? 141  ALA F CA    1 
ATOM   17517 C C     . ALA F 1 141 ? -53.907  -53.539  -49.028 1.00 34.82  ? 141  ALA F C     1 
ATOM   17518 O O     . ALA F 1 141 ? -53.121  -53.313  -48.104 1.00 32.79  ? 141  ALA F O     1 
ATOM   17519 C CB    . ALA F 1 141 ? -53.004  -55.239  -50.700 1.00 23.93  ? 141  ALA F CB    1 
ATOM   17520 N N     . TYR F 1 142 ? -54.662  -52.574  -49.600 1.00 32.39  ? 142  TYR F N     1 
ATOM   17521 C CA    . TYR F 1 142 ? -54.754  -51.231  -49.047 1.00 29.54  ? 142  TYR F CA    1 
ATOM   17522 C C     . TYR F 1 142 ? -55.279  -51.289  -47.598 1.00 31.94  ? 142  TYR F C     1 
ATOM   17523 O O     . TYR F 1 142 ? -54.696  -50.676  -46.685 1.00 31.10  ? 142  TYR F O     1 
ATOM   17524 C CB    . TYR F 1 142 ? -55.472  -50.200  -49.919 1.00 31.58  ? 142  TYR F CB    1 
ATOM   17525 C CG    . TYR F 1 142 ? -55.625  -48.902  -49.124 1.00 35.75  ? 142  TYR F CG    1 
ATOM   17526 C CD1   . TYR F 1 142 ? -54.543  -48.034  -48.945 1.00 30.92  ? 142  TYR F CD1   1 
ATOM   17527 C CD2   . TYR F 1 142 ? -56.830  -48.582  -48.490 1.00 32.66  ? 142  TYR F CD2   1 
ATOM   17528 C CE1   . TYR F 1 142 ? -54.658  -46.889  -48.176 1.00 32.96  ? 142  TYR F CE1   1 
ATOM   17529 C CE2   . TYR F 1 142 ? -56.956  -47.442  -47.705 1.00 31.54  ? 142  TYR F CE2   1 
ATOM   17530 C CZ    . TYR F 1 142 ? -55.872  -46.591  -47.557 1.00 32.39  ? 142  TYR F CZ    1 
ATOM   17531 O OH    . TYR F 1 142 ? -55.973  -45.459  -46.790 1.00 31.08  ? 142  TYR F OH    1 
ATOM   17532 N N     . LEU F 1 143 ? -56.355  -52.062  -47.383 1.00 26.96  ? 143  LEU F N     1 
ATOM   17533 C CA    . LEU F 1 143 ? -56.912  -52.220  -46.048 1.00 28.59  ? 143  LEU F CA    1 
ATOM   17534 C C     . LEU F 1 143 ? -55.860  -52.719  -45.061 1.00 33.81  ? 143  LEU F C     1 
ATOM   17535 O O     . LEU F 1 143 ? -55.848  -52.270  -43.917 1.00 38.50  ? 143  LEU F O     1 
ATOM   17536 C CB    . LEU F 1 143 ? -58.168  -53.076  -46.034 1.00 28.97  ? 143  LEU F CB    1 
ATOM   17537 C CG    . LEU F 1 143 ? -59.315  -52.538  -46.891 1.00 34.24  ? 143  LEU F CG    1 
ATOM   17538 C CD1   . LEU F 1 143 ? -60.521  -53.474  -46.736 1.00 35.43  ? 143  LEU F CD1   1 
ATOM   17539 C CD2   . LEU F 1 143 ? -59.698  -51.102  -46.452 1.00 36.42  ? 143  LEU F CD2   1 
ATOM   17540 N N     . THR F 1 144 ? -54.950  -53.589  -45.512 1.00 36.50  ? 144  THR F N     1 
ATOM   17541 C CA    . THR F 1 144 ? -53.910  -54.125  -44.637 1.00 40.71  ? 144  THR F CA    1 
ATOM   17542 C C     . THR F 1 144 ? -52.937  -53.012  -44.262 1.00 31.33  ? 144  THR F C     1 
ATOM   17543 O O     . THR F 1 144 ? -52.499  -52.938  -43.111 1.00 34.08  ? 144  THR F O     1 
ATOM   17544 C CB    . THR F 1 144 ? -53.176  -55.313  -45.300 1.00 40.63  ? 144  THR F CB    1 
ATOM   17545 O OG1   . THR F 1 144 ? -54.192  -56.292  -45.476 1.00 35.02  ? 144  THR F OG1   1 
ATOM   17546 C CG2   . THR F 1 144 ? -52.071  -55.919  -44.445 1.00 28.97  ? 144  THR F CG2   1 
ATOM   17547 N N     . TYR F 1 145 ? -52.588  -52.183  -45.254 1.00 27.17  ? 145  TYR F N     1 
ATOM   17548 C CA    . TYR F 1 145 ? -51.664  -51.074  -45.064 1.00 30.89  ? 145  TYR F CA    1 
ATOM   17549 C C     . TYR F 1 145 ? -52.270  -50.042  -44.113 1.00 33.61  ? 145  TYR F C     1 
ATOM   17550 O O     . TYR F 1 145 ? -51.610  -49.603  -43.165 1.00 33.81  ? 145  TYR F O     1 
ATOM   17551 C CB    . TYR F 1 145 ? -51.463  -50.511  -46.469 1.00 30.05  ? 145  TYR F CB    1 
ATOM   17552 C CG    . TYR F 1 145 ? -50.652  -49.234  -46.608 1.00 32.67  ? 145  TYR F CG    1 
ATOM   17553 C CD1   . TYR F 1 145 ? -49.282  -49.286  -46.842 1.00 34.20  ? 145  TYR F CD1   1 
ATOM   17554 C CD2   . TYR F 1 145 ? -51.277  -47.981  -46.616 1.00 34.74  ? 145  TYR F CD2   1 
ATOM   17555 C CE1   . TYR F 1 145 ? -48.539  -48.130  -47.049 1.00 36.06  ? 145  TYR F CE1   1 
ATOM   17556 C CE2   . TYR F 1 145 ? -50.544  -46.817  -46.812 1.00 29.65  ? 145  TYR F CE2   1 
ATOM   17557 C CZ    . TYR F 1 145 ? -49.177  -46.893  -47.031 1.00 33.65  ? 145  TYR F CZ    1 
ATOM   17558 O OH    . TYR F 1 145 ? -48.450  -45.758  -47.236 1.00 30.92  ? 145  TYR F OH    1 
ATOM   17559 N N     . LEU F 1 146 ? -53.546  -49.688  -44.351 1.00 32.94  ? 146  LEU F N     1 
ATOM   17560 C CA    . LEU F 1 146 ? -54.240  -48.746  -43.488 1.00 29.13  ? 146  LEU F CA    1 
ATOM   17561 C C     . LEU F 1 146 ? -54.232  -49.276  -42.056 1.00 30.43  ? 146  LEU F C     1 
ATOM   17562 O O     . LEU F 1 146 ? -53.806  -48.588  -41.117 1.00 30.24  ? 146  LEU F O     1 
ATOM   17563 C CB    . LEU F 1 146 ? -55.649  -48.493  -44.014 1.00 29.85  ? 146  LEU F CB    1 
ATOM   17564 C CG    . LEU F 1 146 ? -56.575  -47.698  -43.082 1.00 29.84  ? 146  LEU F CG    1 
ATOM   17565 C CD1   . LEU F 1 146 ? -56.003  -46.290  -42.822 1.00 27.25  ? 146  LEU F CD1   1 
ATOM   17566 C CD2   . LEU F 1 146 ? -57.971  -47.635  -43.686 1.00 24.19  ? 146  LEU F CD2   1 
ATOM   17567 N N     . GLN F 1 147 ? -54.623  -50.547  -41.909 1.00 31.25  ? 147  GLN F N     1 
ATOM   17568 C CA    . GLN F 1 147 ? -54.708  -51.150  -40.584 1.00 31.31  ? 147  GLN F CA    1 
ATOM   17569 C C     . GLN F 1 147 ? -53.343  -51.195  -39.895 1.00 29.37  ? 147  GLN F C     1 
ATOM   17570 O O     . GLN F 1 147 ? -53.231  -50.916  -38.703 1.00 35.58  ? 147  GLN F O     1 
ATOM   17571 C CB    . GLN F 1 147 ? -55.366  -52.519  -40.656 1.00 32.32  ? 147  GLN F CB    1 
ATOM   17572 C CG    . GLN F 1 147 ? -55.536  -53.101  -39.269 1.00 36.89  ? 147  GLN F CG    1 
ATOM   17573 C CD    . GLN F 1 147 ? -56.510  -54.262  -39.222 1.00 41.06  ? 147  GLN F CD    1 
ATOM   17574 O OE1   . GLN F 1 147 ? -57.596  -54.271  -39.825 1.00 43.07  ? 147  GLN F OE1   1 
ATOM   17575 N NE2   . GLN F 1 147 ? -56.099  -55.289  -38.510 1.00 38.36  ? 147  GLN F NE2   1 
ATOM   17576 N N     . LYS F 1 148 ? -52.286  -51.489  -40.653 1.00 30.18  ? 148  LYS F N     1 
ATOM   17577 C CA    . LYS F 1 148 ? -50.954  -51.527  -40.066 1.00 32.02  ? 148  LYS F CA    1 
ATOM   17578 C C     . LYS F 1 148 ? -50.539  -50.120  -39.612 1.00 30.87  ? 148  LYS F C     1 
ATOM   17579 O O     . LYS F 1 148 ? -49.922  -49.964  -38.555 1.00 30.01  ? 148  LYS F O     1 
ATOM   17580 C CB    . LYS F 1 148 ? -49.995  -52.108  -41.114 1.00 38.46  ? 148  LYS F CB    1 
ATOM   17581 C CG    . LYS F 1 148 ? -48.570  -52.348  -40.606 1.00 43.62  ? 148  LYS F CG    1 
ATOM   17582 C CD    . LYS F 1 148 ? -48.553  -53.716  -39.944 1.00 55.08  ? 148  LYS F CD    1 
ATOM   17583 C CE    . LYS F 1 148 ? -47.615  -53.879  -38.797 1.00 66.10  ? 148  LYS F CE    1 
ATOM   17584 N NZ    . LYS F 1 148 ? -47.820  -55.261  -38.364 1.00 73.14  ? 148  LYS F NZ    1 
ATOM   17585 N N     . SER F 1 149 ? -50.860  -49.094  -40.429 1.00 26.53  ? 149  SER F N     1 
ATOM   17586 C CA    . SER F 1 149 ? -50.491  -47.729  -40.084 1.00 29.47  ? 149  SER F CA    1 
ATOM   17587 C C     . SER F 1 149 ? -51.186  -47.298  -38.789 1.00 28.25  ? 149  SER F C     1 
ATOM   17588 O O     . SER F 1 149 ? -50.586  -46.617  -37.962 1.00 28.87  ? 149  SER F O     1 
ATOM   17589 C CB    . SER F 1 149 ? -50.720  -46.752  -41.210 1.00 27.85  ? 149  SER F CB    1 
ATOM   17590 O OG    . SER F 1 149 ? -52.105  -46.485  -41.351 1.00 30.69  ? 149  SER F OG    1 
ATOM   17591 N N     . VAL F 1 150 ? -52.414  -47.788  -38.565 1.00 27.97  ? 150  VAL F N     1 
ATOM   17592 C CA    . VAL F 1 150 ? -53.109  -47.483  -37.327 1.00 28.31  ? 150  VAL F CA    1 
ATOM   17593 C C     . VAL F 1 150 ? -52.547  -48.292  -36.164 1.00 31.32  ? 150  VAL F C     1 
ATOM   17594 O O     . VAL F 1 150 ? -52.479  -47.811  -35.025 1.00 31.93  ? 150  VAL F O     1 
ATOM   17595 C CB    . VAL F 1 150 ? -54.629  -47.670  -37.518 1.00 28.61  ? 150  VAL F CB    1 
ATOM   17596 C CG1   . VAL F 1 150 ? -55.388  -47.549  -36.208 1.00 28.70  ? 150  VAL F CG1   1 
ATOM   17597 C CG2   . VAL F 1 150 ? -55.184  -46.715  -38.563 1.00 23.52  ? 150  VAL F CG2   1 
ATOM   17598 N N     . GLU F 1 151 ? -52.144  -49.533  -36.455 1.00 35.40  ? 151  GLU F N     1 
ATOM   17599 C CA    . GLU F 1 151 ? -51.566  -50.392  -35.430 1.00 35.73  ? 151  GLU F CA    1 
ATOM   17600 C C     . GLU F 1 151 ? -50.287  -49.778  -34.855 1.00 31.59  ? 151  GLU F C     1 
ATOM   17601 O O     . GLU F 1 151 ? -50.073  -49.811  -33.641 1.00 33.75  ? 151  GLU F O     1 
ATOM   17602 C CB    . GLU F 1 151 ? -51.350  -51.785  -36.010 1.00 43.24  ? 151  GLU F CB    1 
ATOM   17603 C CG    . GLU F 1 151 ? -50.788  -52.772  -34.987 1.00 50.42  ? 151  GLU F CG    1 
ATOM   17604 C CD    . GLU F 1 151 ? -50.153  -54.024  -35.591 1.00 52.98  ? 151  GLU F CD    1 
ATOM   17605 O OE1   . GLU F 1 151 ? -50.446  -54.411  -36.728 1.00 54.21  ? 151  GLU F OE1   1 
ATOM   17606 O OE2   . GLU F 1 151 ? -49.268  -54.581  -34.930 1.00 54.23  ? 151  GLU F OE2   1 
ATOM   17607 N N     . VAL F 1 152 ? -49.447  -49.184  -35.709 1.00 29.92  ? 152  VAL F N     1 
ATOM   17608 C CA    . VAL F 1 152 ? -48.258  -48.491  -35.210 1.00 30.38  ? 152  VAL F CA    1 
ATOM   17609 C C     . VAL F 1 152 ? -48.655  -47.418  -34.191 1.00 34.28  ? 152  VAL F C     1 
ATOM   17610 O O     . VAL F 1 152 ? -47.998  -47.281  -33.152 1.00 35.29  ? 152  VAL F O     1 
ATOM   17611 C CB    . VAL F 1 152 ? -47.424  -47.900  -36.362 1.00 27.09  ? 152  VAL F CB    1 
ATOM   17612 C CG1   . VAL F 1 152 ? -46.313  -46.986  -35.868 1.00 23.50  ? 152  VAL F CG1   1 
ATOM   17613 C CG2   . VAL F 1 152 ? -46.870  -49.015  -37.239 1.00 28.88  ? 152  VAL F CG2   1 
ATOM   17614 N N     . LEU F 1 153 ? -49.725  -46.655  -34.500 1.00 31.27  ? 153  LEU F N     1 
ATOM   17615 C CA    . LEU F 1 153 ? -50.163  -45.569  -33.637 1.00 30.84  ? 153  LEU F CA    1 
ATOM   17616 C C     . LEU F 1 153 ? -50.683  -46.150  -32.326 1.00 32.05  ? 153  LEU F C     1 
ATOM   17617 O O     . LEU F 1 153 ? -50.519  -45.521  -31.283 1.00 30.06  ? 153  LEU F O     1 
ATOM   17618 C CB    . LEU F 1 153 ? -51.193  -44.647  -34.291 1.00 26.24  ? 153  LEU F CB    1 
ATOM   17619 C CG    . LEU F 1 153 ? -50.672  -43.819  -35.458 1.00 27.49  ? 153  LEU F CG    1 
ATOM   17620 C CD1   . LEU F 1 153 ? -51.821  -43.234  -36.249 1.00 26.75  ? 153  LEU F CD1   1 
ATOM   17621 C CD2   . LEU F 1 153 ? -49.701  -42.737  -34.989 1.00 24.19  ? 153  LEU F CD2   1 
ATOM   17622 N N     . CYS F 1 154 ? -51.290  -47.346  -32.390 1.00 33.70  ? 154  CYS F N     1 
ATOM   17623 C CA    . CYS F 1 154 ? -51.852  -47.982  -31.210 1.00 34.05  ? 154  CYS F CA    1 
ATOM   17624 C C     . CYS F 1 154 ? -50.798  -48.637  -30.313 1.00 37.29  ? 154  CYS F C     1 
ATOM   17625 O O     . CYS F 1 154 ? -51.135  -49.017  -29.198 1.00 33.45  ? 154  CYS F O     1 
ATOM   17626 C CB    . CYS F 1 154 ? -52.778  -49.125  -31.585 1.00 34.78  ? 154  CYS F CB    1 
ATOM   17627 S SG    . CYS F 1 154 ? -54.344  -48.581  -32.317 1.00 36.24  ? 154  CYS F SG    1 
ATOM   17628 N N     . ARG F 1 155 ? -49.538  -48.784  -30.775 1.00 42.75  ? 155  ARG F N     1 
ATOM   17629 C CA    . ARG F 1 155 ? -48.588  -49.607  -30.030 1.00 39.12  ? 155  ARG F CA    1 
ATOM   17630 C C     . ARG F 1 155 ? -47.334  -48.853  -29.611 1.00 39.21  ? 155  ARG F C     1 
ATOM   17631 O O     . ARG F 1 155 ? -46.569  -49.386  -28.826 1.00 47.57  ? 155  ARG F O     1 
ATOM   17632 C CB    . ARG F 1 155 ? -48.165  -50.869  -30.793 1.00 34.72  ? 155  ARG F CB    1 
ATOM   17633 C CG    . ARG F 1 155 ? -49.380  -51.763  -31.000 1.00 43.86  ? 155  ARG F CG    1 
ATOM   17634 C CD    . ARG F 1 155 ? -49.027  -52.988  -31.786 1.00 45.60  ? 155  ARG F CD    1 
ATOM   17635 N NE    . ARG F 1 155 ? -48.126  -53.833  -30.994 1.00 58.22  ? 155  ARG F NE    1 
ATOM   17636 C CZ    . ARG F 1 155 ? -47.440  -54.883  -31.441 1.00 57.44  ? 155  ARG F CZ    1 
ATOM   17637 N NH1   . ARG F 1 155 ? -46.480  -55.406  -30.693 1.00 53.93  ? 155  ARG F NH1   1 
ATOM   17638 N NH2   . ARG F 1 155 ? -47.619  -55.343  -32.667 1.00 45.58  ? 155  ARG F NH2   1 
ATOM   17639 N N     . ASN F 1 156 ? -47.080  -47.646  -30.122 1.00 37.87  ? 156  ASN F N     1 
ATOM   17640 C CA    . ASN F 1 156 ? -45.766  -47.056  -29.896 1.00 31.63  ? 156  ASN F CA    1 
ATOM   17641 C C     . ASN F 1 156 ? -45.811  -45.742  -29.119 1.00 36.55  ? 156  ASN F C     1 
ATOM   17642 O O     . ASN F 1 156 ? -44.783  -45.060  -29.021 1.00 34.81  ? 156  ASN F O     1 
ATOM   17643 C CB    . ASN F 1 156 ? -45.027  -46.858  -31.218 1.00 34.71  ? 156  ASN F CB    1 
ATOM   17644 C CG    . ASN F 1 156 ? -44.577  -48.170  -31.786 1.00 37.30  ? 156  ASN F CG    1 
ATOM   17645 O OD1   . ASN F 1 156 ? -43.475  -48.602  -31.450 1.00 51.12  ? 156  ASN F OD1   1 
ATOM   17646 N ND2   . ASN F 1 156 ? -45.416  -48.842  -32.559 1.00 34.73  ? 156  ASN F ND2   1 
ATOM   17647 N N     . TYR F 1 157 ? -46.995  -45.358  -28.596 1.00 31.17  ? 157  TYR F N     1 
ATOM   17648 C CA    . TYR F 1 157 ? -47.131  -44.005  -28.081 1.00 32.68  ? 157  TYR F CA    1 
ATOM   17649 C C     . TYR F 1 157 ? -47.810  -43.997  -26.713 1.00 36.77  ? 157  TYR F C     1 
ATOM   17650 O O     . TYR F 1 157 ? -48.100  -42.932  -26.210 1.00 38.80  ? 157  TYR F O     1 
ATOM   17651 C CB    . TYR F 1 157 ? -47.839  -43.136  -29.130 1.00 30.79  ? 157  TYR F CB    1 
ATOM   17652 C CG    . TYR F 1 157 ? -47.060  -43.102  -30.436 1.00 25.96  ? 157  TYR F CG    1 
ATOM   17653 C CD1   . TYR F 1 157 ? -45.933  -42.328  -30.561 1.00 26.05  ? 157  TYR F CD1   1 
ATOM   17654 C CD2   . TYR F 1 157 ? -47.419  -43.888  -31.519 1.00 26.73  ? 157  TYR F CD2   1 
ATOM   17655 C CE1   . TYR F 1 157 ? -45.170  -42.312  -31.727 1.00 27.73  ? 157  TYR F CE1   1 
ATOM   17656 C CE2   . TYR F 1 157 ? -46.668  -43.895  -32.689 1.00 25.84  ? 157  TYR F CE2   1 
ATOM   17657 C CZ    . TYR F 1 157 ? -45.543  -43.100  -32.798 1.00 27.25  ? 157  TYR F CZ    1 
ATOM   17658 O OH    . TYR F 1 157 ? -44.768  -43.084  -33.927 1.00 26.76  ? 157  TYR F OH    1 
ATOM   17659 N N     . GLY F 1 158 ? -48.045  -45.167  -26.109 1.00 38.91  ? 158  GLY F N     1 
ATOM   17660 C CA    . GLY F 1 158 ? -48.760  -45.264  -24.848 1.00 39.19  ? 158  GLY F CA    1 
ATOM   17661 C C     . GLY F 1 158 ? -50.267  -45.111  -25.056 1.00 42.70  ? 158  GLY F C     1 
ATOM   17662 O O     . GLY F 1 158 ? -50.743  -45.216  -26.193 1.00 42.62  ? 158  GLY F O     1 
ATOM   17663 N N     . PRO F 1 159 ? -51.064  -44.861  -23.982 1.00 44.06  ? 159  PRO F N     1 
ATOM   17664 C CA    . PRO F 1 159 ? -52.514  -44.681  -24.130 1.00 43.13  ? 159  PRO F CA    1 
ATOM   17665 C C     . PRO F 1 159 ? -52.869  -43.462  -24.994 1.00 39.94  ? 159  PRO F C     1 
ATOM   17666 O O     . PRO F 1 159 ? -52.284  -42.380  -24.854 1.00 33.87  ? 159  PRO F O     1 
ATOM   17667 C CB    . PRO F 1 159 ? -53.052  -44.542  -22.701 1.00 42.97  ? 159  PRO F CB    1 
ATOM   17668 C CG    . PRO F 1 159 ? -51.837  -44.687  -21.780 1.00 48.93  ? 159  PRO F CG    1 
ATOM   17669 C CD    . PRO F 1 159 ? -50.583  -44.689  -22.600 1.00 44.36  ? 159  PRO F CD    1 
ATOM   17670 N N     . VAL F 1 160 ? -53.801  -43.657  -25.927 1.00 32.10  ? 160  VAL F N     1 
ATOM   17671 C CA    . VAL F 1 160 ? -54.116  -42.628  -26.903 1.00 35.78  ? 160  VAL F CA    1 
ATOM   17672 C C     . VAL F 1 160 ? -55.526  -42.137  -26.605 1.00 33.58  ? 160  VAL F C     1 
ATOM   17673 O O     . VAL F 1 160 ? -56.401  -42.932  -26.299 1.00 32.34  ? 160  VAL F O     1 
ATOM   17674 C CB    . VAL F 1 160 ? -54.004  -43.366  -28.249 1.00 42.40  ? 160  VAL F CB    1 
ATOM   17675 C CG1   . VAL F 1 160 ? -54.555  -42.558  -29.413 1.00 46.18  ? 160  VAL F CG1   1 
ATOM   17676 C CG2   . VAL F 1 160 ? -52.543  -43.679  -28.523 1.00 50.37  ? 160  VAL F CG2   1 
ATOM   17677 N N     . GLY F 1 161 ? -55.749  -40.825  -26.686 1.00 31.04  ? 161  GLY F N     1 
ATOM   17678 C CA    . GLY F 1 161 ? -57.068  -40.300  -26.359 1.00 27.53  ? 161  GLY F CA    1 
ATOM   17679 C C     . GLY F 1 161 ? -58.117  -40.794  -27.346 1.00 27.81  ? 161  GLY F C     1 
ATOM   17680 O O     . GLY F 1 161 ? -59.221  -41.177  -26.957 1.00 29.55  ? 161  GLY F O     1 
ATOM   17681 N N     . GLY F 1 162 ? -57.753  -40.817  -28.636 1.00 25.46  ? 162  GLY F N     1 
ATOM   17682 C CA    . GLY F 1 162 ? -58.723  -41.211  -29.632 1.00 26.69  ? 162  GLY F CA    1 
ATOM   17683 C C     . GLY F 1 162 ? -58.140  -41.169  -31.044 1.00 25.70  ? 162  GLY F C     1 
ATOM   17684 O O     . GLY F 1 162 ? -57.024  -40.723  -31.268 1.00 26.28  ? 162  GLY F O     1 
ATOM   17685 N N     . PHE F 1 163 ? -58.957  -41.638  -31.985 1.00 22.52  ? 163  PHE F N     1 
ATOM   17686 C CA    . PHE F 1 163 ? -58.673  -41.678  -33.399 1.00 24.79  ? 163  PHE F CA    1 
ATOM   17687 C C     . PHE F 1 163 ? -59.835  -40.971  -34.076 1.00 27.02  ? 163  PHE F C     1 
ATOM   17688 O O     . PHE F 1 163 ? -60.989  -41.105  -33.647 1.00 28.11  ? 163  PHE F O     1 
ATOM   17689 C CB    . PHE F 1 163 ? -58.663  -43.140  -33.889 1.00 26.99  ? 163  PHE F CB    1 
ATOM   17690 C CG    . PHE F 1 163 ? -57.399  -43.865  -33.448 1.00 27.61  ? 163  PHE F CG    1 
ATOM   17691 C CD1   . PHE F 1 163 ? -56.255  -43.845  -34.243 1.00 25.82  ? 163  PHE F CD1   1 
ATOM   17692 C CD2   . PHE F 1 163 ? -57.352  -44.524  -32.221 1.00 30.61  ? 163  PHE F CD2   1 
ATOM   17693 C CE1   . PHE F 1 163 ? -55.082  -44.468  -33.808 1.00 33.20  ? 163  PHE F CE1   1 
ATOM   17694 C CE2   . PHE F 1 163 ? -56.182  -45.156  -31.792 1.00 35.59  ? 163  PHE F CE2   1 
ATOM   17695 C CZ    . PHE F 1 163 ? -55.050  -45.147  -32.592 1.00 29.74  ? 163  PHE F CZ    1 
ATOM   17696 N N     . TRP F 1 164 ? -59.494  -40.244  -35.138 1.00 26.17  ? 164  TRP F N     1 
ATOM   17697 C CA    . TRP F 1 164 ? -60.437  -39.442  -35.888 1.00 25.66  ? 164  TRP F CA    1 
ATOM   17698 C C     . TRP F 1 164 ? -60.290  -39.869  -37.353 1.00 26.45  ? 164  TRP F C     1 
ATOM   17699 O O     . TRP F 1 164 ? -59.311  -39.523  -38.024 1.00 27.28  ? 164  TRP F O     1 
ATOM   17700 C CB    . TRP F 1 164 ? -60.107  -37.956  -35.645 1.00 22.90  ? 164  TRP F CB    1 
ATOM   17701 C CG    . TRP F 1 164 ? -61.260  -36.980  -35.764 1.00 24.62  ? 164  TRP F CG    1 
ATOM   17702 C CD1   . TRP F 1 164 ? -61.945  -36.389  -34.733 1.00 22.78  ? 164  TRP F CD1   1 
ATOM   17703 C CD2   . TRP F 1 164 ? -61.837  -36.437  -36.988 1.00 23.34  ? 164  TRP F CD2   1 
ATOM   17704 N NE1   . TRP F 1 164 ? -62.911  -35.538  -35.222 1.00 20.28  ? 164  TRP F NE1   1 
ATOM   17705 C CE2   . TRP F 1 164 ? -62.856  -35.525  -36.593 1.00 23.67  ? 164  TRP F CE2   1 
ATOM   17706 C CE3   . TRP F 1 164 ? -61.570  -36.605  -38.363 1.00 21.47  ? 164  TRP F CE3   1 
ATOM   17707 C CZ2   . TRP F 1 164 ? -63.598  -34.787  -37.528 1.00 22.32  ? 164  TRP F CZ2   1 
ATOM   17708 C CZ3   . TRP F 1 164 ? -62.296  -35.863  -39.280 1.00 22.51  ? 164  TRP F CZ3   1 
ATOM   17709 C CH2   . TRP F 1 164 ? -63.288  -34.954  -38.871 1.00 20.14  ? 164  TRP F CH2   1 
ATOM   17710 N N     . PHE F 1 165 ? -61.245  -40.685  -37.812 1.00 27.08  ? 165  PHE F N     1 
ATOM   17711 C CA    . PHE F 1 165 ? -61.125  -41.337  -39.108 1.00 27.32  ? 165  PHE F CA    1 
ATOM   17712 C C     . PHE F 1 165 ? -61.915  -40.551  -40.143 1.00 27.89  ? 165  PHE F C     1 
ATOM   17713 O O     . PHE F 1 165 ? -63.097  -40.235  -39.955 1.00 24.53  ? 165  PHE F O     1 
ATOM   17714 C CB    . PHE F 1 165 ? -61.636  -42.785  -39.122 1.00 24.28  ? 165  PHE F CB    1 
ATOM   17715 C CG    . PHE F 1 165 ? -60.610  -43.684  -38.442 1.00 30.03  ? 165  PHE F CG    1 
ATOM   17716 C CD1   . PHE F 1 165 ? -59.376  -43.947  -39.042 1.00 27.42  ? 165  PHE F CD1   1 
ATOM   17717 C CD2   . PHE F 1 165 ? -60.882  -44.251  -37.196 1.00 30.55  ? 165  PHE F CD2   1 
ATOM   17718 C CE1   . PHE F 1 165 ? -58.454  -44.767  -38.416 1.00 28.86  ? 165  PHE F CE1   1 
ATOM   17719 C CE2   . PHE F 1 165 ? -59.969  -45.075  -36.567 1.00 29.13  ? 165  PHE F CE2   1 
ATOM   17720 C CZ    . PHE F 1 165 ? -58.739  -45.307  -37.163 1.00 34.17  ? 165  PHE F CZ    1 
ATOM   17721 N N     . ASP F 1 166 ? -61.260  -40.308  -41.271 1.00 27.51  ? 166  ASP F N     1 
ATOM   17722 C CA    . ASP F 1 166 ? -61.898  -39.533  -42.305 1.00 30.92  ? 166  ASP F CA    1 
ATOM   17723 C C     . ASP F 1 166 ? -61.697  -40.196  -43.670 1.00 31.71  ? 166  ASP F C     1 
ATOM   17724 O O     . ASP F 1 166 ? -60.558  -40.330  -44.125 1.00 31.55  ? 166  ASP F O     1 
ATOM   17725 C CB    . ASP F 1 166 ? -61.284  -38.139  -42.261 1.00 27.98  ? 166  ASP F CB    1 
ATOM   17726 C CG    . ASP F 1 166 ? -61.715  -37.250  -43.414 1.00 31.98  ? 166  ASP F CG    1 
ATOM   17727 O OD1   . ASP F 1 166 ? -62.924  -37.284  -43.750 1.00 35.00  ? 166  ASP F OD1   1 
ATOM   17728 O OD2   . ASP F 1 166 ? -60.844  -36.561  -43.968 1.00 34.63  ? 166  ASP F OD2   1 
ATOM   17729 N N     . GLY F 1 167 ? -62.785  -40.549  -44.370 1.00 36.09  ? 167  GLY F N     1 
ATOM   17730 C CA    . GLY F 1 167 ? -62.573  -40.763  -45.808 1.00 51.55  ? 167  GLY F CA    1 
ATOM   17731 C C     . GLY F 1 167 ? -63.204  -42.030  -46.408 1.00 60.02  ? 167  GLY F C     1 
ATOM   17732 O O     . GLY F 1 167 ? -63.047  -42.310  -47.614 1.00 63.49  ? 167  GLY F O     1 
ATOM   17733 N N     . ASN F 1 168 ? -63.920  -42.798  -45.571 1.00 58.80  ? 168  ASN F N     1 
ATOM   17734 C CA    . ASN F 1 168 ? -64.644  -43.969  -46.060 1.00 55.61  ? 168  ASN F CA    1 
ATOM   17735 C C     . ASN F 1 168 ? -65.706  -43.527  -47.071 1.00 63.56  ? 168  ASN F C     1 
ATOM   17736 O O     . ASN F 1 168 ? -66.086  -44.314  -47.939 1.00 65.91  ? 168  ASN F O     1 
ATOM   17737 C CB    . ASN F 1 168 ? -65.255  -44.815  -44.946 1.00 60.75  ? 168  ASN F CB    1 
ATOM   17738 C CG    . ASN F 1 168 ? -64.243  -45.527  -44.084 1.00 58.08  ? 168  ASN F CG    1 
ATOM   17739 O OD1   . ASN F 1 168 ? -63.063  -45.163  -44.020 1.00 54.02  ? 168  ASN F OD1   1 
ATOM   17740 N ND2   . ASN F 1 168 ? -64.717  -46.540  -43.385 1.00 70.65  ? 168  ASN F ND2   1 
ATOM   17741 N N     . TRP F 1 169 ? -66.141  -42.253  -46.970 1.00 57.74  ? 169  TRP F N     1 
ATOM   17742 C CA    . TRP F 1 169 ? -67.089  -41.626  -47.886 1.00 55.89  ? 169  TRP F CA    1 
ATOM   17743 C C     . TRP F 1 169 ? -66.595  -41.664  -49.340 1.00 58.03  ? 169  TRP F C     1 
ATOM   17744 O O     . TRP F 1 169 ? -67.407  -41.458  -50.249 1.00 49.02  ? 169  TRP F O     1 
ATOM   17745 C CB    . TRP F 1 169 ? -67.404  -40.182  -47.441 1.00 57.28  ? 169  TRP F CB    1 
ATOM   17746 C CG    . TRP F 1 169 ? -66.179  -39.403  -47.014 1.00 59.61  ? 169  TRP F CG    1 
ATOM   17747 C CD1   . TRP F 1 169 ? -65.783  -39.143  -45.733 1.00 55.38  ? 169  TRP F CD1   1 
ATOM   17748 C CD2   . TRP F 1 169 ? -65.162  -38.824  -47.877 1.00 46.69  ? 169  TRP F CD2   1 
ATOM   17749 N NE1   . TRP F 1 169 ? -64.611  -38.428  -45.736 1.00 42.28  ? 169  TRP F NE1   1 
ATOM   17750 C CE2   . TRP F 1 169 ? -64.208  -38.217  -47.029 1.00 45.35  ? 169  TRP F CE2   1 
ATOM   17751 C CE3   . TRP F 1 169 ? -64.986  -38.747  -49.268 1.00 45.51  ? 169  TRP F CE3   1 
ATOM   17752 C CZ2   . TRP F 1 169 ? -63.091  -37.552  -47.527 1.00 48.56  ? 169  TRP F CZ2   1 
ATOM   17753 C CZ3   . TRP F 1 169 ? -63.886  -38.094  -49.772 1.00 52.69  ? 169  TRP F CZ3   1 
ATOM   17754 C CH2   . TRP F 1 169 ? -62.952  -37.514  -48.902 1.00 59.26  ? 169  TRP F CH2   1 
ATOM   17755 N N     . ASN F 1 170 ? -65.277  -41.897  -49.565 1.00 57.19  ? 170  ASN F N     1 
ATOM   17756 C CA    . ASN F 1 170 ? -64.756  -41.945  -50.920 1.00 47.62  ? 170  ASN F CA    1 
ATOM   17757 C C     . ASN F 1 170 ? -65.252  -43.197  -51.663 1.00 44.70  ? 170  ASN F C     1 
ATOM   17758 O O     . ASN F 1 170 ? -65.433  -43.170  -52.879 1.00 41.97  ? 170  ASN F O     1 
ATOM   17759 C CB    . ASN F 1 170 ? -63.251  -41.798  -50.986 1.00 44.33  ? 170  ASN F CB    1 
ATOM   17760 C CG    . ASN F 1 170 ? -62.742  -42.013  -52.403 1.00 54.69  ? 170  ASN F CG    1 
ATOM   17761 O OD1   . ASN F 1 170 ? -62.192  -43.082  -52.743 1.00 50.03  ? 170  ASN F OD1   1 
ATOM   17762 N ND2   . ASN F 1 170 ? -62.946  -41.037  -53.275 1.00 43.67  ? 170  ASN F ND2   1 
ATOM   17763 N N     . LYS F 1 171 ? -65.436  -44.313  -50.950 1.00 44.46  ? 171  LYS F N     1 
ATOM   17764 C CA    . LYS F 1 171 ? -66.012  -45.522  -51.531 1.00 48.98  ? 171  LYS F CA    1 
ATOM   17765 C C     . LYS F 1 171 ? -67.160  -45.989  -50.633 1.00 55.58  ? 171  LYS F C     1 
ATOM   17766 O O     . LYS F 1 171 ? -66.948  -46.846  -49.768 1.00 50.13  ? 171  LYS F O     1 
ATOM   17767 C CB    . LYS F 1 171 ? -64.947  -46.623  -51.625 1.00 43.61  ? 171  LYS F CB    1 
ATOM   17768 C CG    . LYS F 1 171 ? -63.768  -46.378  -52.557 1.00 44.34  ? 171  LYS F CG    1 
ATOM   17769 C CD    . LYS F 1 171 ? -62.706  -47.480  -52.586 1.00 49.78  ? 171  LYS F CD    1 
ATOM   17770 C CE    . LYS F 1 171 ? -62.290  -47.698  -54.034 1.00 58.75  ? 171  LYS F CE    1 
ATOM   17771 N NZ    . LYS F 1 171 ? -60.868  -48.012  -54.269 1.00 60.37  ? 171  LYS F NZ    1 
ATOM   17772 N N     . LYS F 1 172 ? -68.362  -45.403  -50.811 1.00 67.79  ? 172  LYS F N     1 
ATOM   17773 C CA    . LYS F 1 172 ? -69.490  -45.648  -49.909 1.00 73.49  ? 172  LYS F CA    1 
ATOM   17774 C C     . LYS F 1 172 ? -69.934  -47.115  -49.957 1.00 73.37  ? 172  LYS F C     1 
ATOM   17775 O O     . LYS F 1 172 ? -70.495  -47.614  -48.996 1.00 59.33  ? 172  LYS F O     1 
ATOM   17776 C CB    . LYS F 1 172 ? -70.686  -44.713  -50.142 1.00 70.36  ? 172  LYS F CB    1 
ATOM   17777 C CG    . LYS F 1 172 ? -70.430  -43.277  -49.696 1.00 87.90  ? 172  LYS F CG    1 
ATOM   17778 C CD    . LYS F 1 172 ? -71.373  -42.178  -50.169 1.00 88.01  ? 172  LYS F CD    1 
ATOM   17779 C CE    . LYS F 1 172 ? -71.122  -41.661  -51.567 1.00 89.91  ? 172  LYS F CE    1 
ATOM   17780 N NZ    . LYS F 1 172 ? -72.000  -40.548  -51.927 1.00 83.16  ? 172  LYS F NZ    1 
ATOM   17781 N N     . ASP F 1 173 ? -69.666  -47.786  -51.060 1.00 85.10  ? 173  ASP F N     1 
ATOM   17782 C CA    . ASP F 1 173 ? -70.107  -49.115  -51.439 1.00 78.60  ? 173  ASP F CA    1 
ATOM   17783 C C     . ASP F 1 173 ? -69.196  -50.232  -50.898 1.00 71.21  ? 173  ASP F C     1 
ATOM   17784 O O     . ASP F 1 173 ? -69.648  -51.349  -50.692 1.00 65.00  ? 173  ASP F O     1 
ATOM   17785 C CB    . ASP F 1 173 ? -69.925  -49.170  -52.952 1.00 92.27  ? 173  ASP F CB    1 
ATOM   17786 C CG    . ASP F 1 173 ? -68.633  -48.524  -53.498 1.00 91.91  ? 173  ASP F CG    1 
ATOM   17787 O OD1   . ASP F 1 173 ? -68.355  -47.341  -53.159 1.00 60.95  ? 173  ASP F OD1   1 
ATOM   17788 O OD2   . ASP F 1 173 ? -67.877  -49.183  -54.308 1.00 85.58  ? 173  ASP F OD2   1 
ATOM   17789 N N     . ALA F 1 174 ? -67.908  -49.931  -50.688 1.00 64.04  ? 174  ALA F N     1 
ATOM   17790 C CA    . ALA F 1 174 ? -66.886  -50.943  -50.454 1.00 53.46  ? 174  ALA F CA    1 
ATOM   17791 C C     . ALA F 1 174 ? -67.010  -51.524  -49.054 1.00 46.50  ? 174  ALA F C     1 
ATOM   17792 O O     . ALA F 1 174 ? -67.582  -50.904  -48.154 1.00 45.17  ? 174  ALA F O     1 
ATOM   17793 C CB    . ALA F 1 174 ? -65.504  -50.355  -50.664 1.00 52.29  ? 174  ALA F CB    1 
ATOM   17794 N N     . ASP F 1 175 ? -66.464  -52.733  -48.887 1.00 47.86  ? 175  ASP F N     1 
ATOM   17795 C CA    . ASP F 1 175 ? -66.330  -53.323  -47.565 1.00 44.54  ? 175  ASP F CA    1 
ATOM   17796 C C     . ASP F 1 175 ? -65.008  -52.839  -46.979 1.00 43.67  ? 175  ASP F C     1 
ATOM   17797 O O     . ASP F 1 175 ? -63.938  -53.206  -47.473 1.00 42.94  ? 175  ASP F O     1 
ATOM   17798 C CB    . ASP F 1 175 ? -66.432  -54.839  -47.636 1.00 41.16  ? 175  ASP F CB    1 
ATOM   17799 C CG    . ASP F 1 175 ? -66.392  -55.591  -46.305 1.00 45.43  ? 175  ASP F CG    1 
ATOM   17800 O OD1   . ASP F 1 175 ? -66.122  -54.958  -45.255 1.00 41.94  ? 175  ASP F OD1   1 
ATOM   17801 O OD2   . ASP F 1 175 ? -66.667  -56.816  -46.315 1.00 51.86  ? 175  ASP F OD2   1 
ATOM   17802 N N     . TRP F 1 176 ? -65.090  -52.031  -45.919 1.00 41.52  ? 176  TRP F N     1 
ATOM   17803 C CA    . TRP F 1 176 ? -63.913  -51.418  -45.311 1.00 37.88  ? 176  TRP F CA    1 
ATOM   17804 C C     . TRP F 1 176 ? -63.380  -52.258  -44.169 1.00 35.66  ? 176  TRP F C     1 
ATOM   17805 O O     . TRP F 1 176 ? -62.384  -51.865  -43.568 1.00 39.74  ? 176  TRP F O     1 
ATOM   17806 C CB    . TRP F 1 176 ? -64.220  -49.986  -44.817 1.00 32.39  ? 176  TRP F CB    1 
ATOM   17807 C CG    . TRP F 1 176 ? -64.225  -48.974  -45.918 1.00 27.83  ? 176  TRP F CG    1 
ATOM   17808 C CD1   . TRP F 1 176 ? -65.294  -48.619  -46.677 1.00 33.21  ? 176  TRP F CD1   1 
ATOM   17809 C CD2   . TRP F 1 176 ? -63.115  -48.165  -46.375 1.00 31.15  ? 176  TRP F CD2   1 
ATOM   17810 N NE1   . TRP F 1 176 ? -64.937  -47.675  -47.605 1.00 31.17  ? 176  TRP F NE1   1 
ATOM   17811 C CE2   . TRP F 1 176 ? -63.612  -47.360  -47.434 1.00 30.75  ? 176  TRP F CE2   1 
ATOM   17812 C CE3   . TRP F 1 176 ? -61.765  -48.049  -46.005 1.00 29.31  ? 176  TRP F CE3   1 
ATOM   17813 C CZ2   . TRP F 1 176 ? -62.812  -46.453  -48.122 1.00 29.42  ? 176  TRP F CZ2   1 
ATOM   17814 C CZ3   . TRP F 1 176 ? -60.980  -47.142  -46.681 1.00 27.32  ? 176  TRP F CZ3   1 
ATOM   17815 C CH2   . TRP F 1 176 ? -61.498  -46.358  -47.723 1.00 30.12  ? 176  TRP F CH2   1 
ATOM   17816 N N     . HIS F 1 177 ? -64.069  -53.363  -43.836 1.00 37.24  ? 177  HIS F N     1 
ATOM   17817 C CA    . HIS F 1 177 ? -63.566  -54.271  -42.804 1.00 38.53  ? 177  HIS F CA    1 
ATOM   17818 C C     . HIS F 1 177 ? -63.390  -53.489  -41.502 1.00 36.66  ? 177  HIS F C     1 
ATOM   17819 O O     . HIS F 1 177 ? -62.347  -53.569  -40.850 1.00 39.98  ? 177  HIS F O     1 
ATOM   17820 C CB    . HIS F 1 177 ? -62.323  -55.059  -43.275 1.00 39.75  ? 177  HIS F CB    1 
ATOM   17821 C CG    . HIS F 1 177 ? -62.599  -56.076  -44.355 1.00 48.63  ? 177  HIS F CG    1 
ATOM   17822 N ND1   . HIS F 1 177 ? -63.015  -57.383  -44.162 1.00 51.41  ? 177  HIS F ND1   1 
ATOM   17823 C CD2   . HIS F 1 177 ? -62.550  -55.912  -45.687 1.00 48.96  ? 177  HIS F CD2   1 
ATOM   17824 C CE1   . HIS F 1 177 ? -63.234  -57.962  -45.338 1.00 48.86  ? 177  HIS F CE1   1 
ATOM   17825 N NE2   . HIS F 1 177 ? -62.935  -57.093  -46.280 1.00 51.20  ? 177  HIS F NE2   1 
ATOM   17826 N N     . LEU F 1 178 ? -64.444  -52.764  -41.114 1.00 35.75  ? 178  LEU F N     1 
ATOM   17827 C CA    . LEU F 1 178 ? -64.398  -51.946  -39.905 1.00 34.38  ? 178  LEU F CA    1 
ATOM   17828 C C     . LEU F 1 178 ? -64.309  -52.818  -38.652 1.00 36.74  ? 178  LEU F C     1 
ATOM   17829 O O     . LEU F 1 178 ? -63.563  -52.458  -37.727 1.00 38.35  ? 178  LEU F O     1 
ATOM   17830 C CB    . LEU F 1 178 ? -65.534  -50.922  -39.838 1.00 31.68  ? 178  LEU F CB    1 
ATOM   17831 C CG    . LEU F 1 178 ? -65.565  -49.932  -41.009 1.00 35.38  ? 178  LEU F CG    1 
ATOM   17832 C CD1   . LEU F 1 178 ? -66.809  -49.025  -40.962 1.00 28.85  ? 178  LEU F CD1   1 
ATOM   17833 C CD2   . LEU F 1 178 ? -64.267  -49.126  -41.039 1.00 31.73  ? 178  LEU F CD2   1 
ATOM   17834 N N     . PRO F 1 179 ? -65.046  -53.965  -38.559 1.00 35.74  ? 179  PRO F N     1 
ATOM   17835 C CA    . PRO F 1 179 ? -64.900  -54.851  -37.395 1.00 30.45  ? 179  PRO F CA    1 
ATOM   17836 C C     . PRO F 1 179 ? -63.443  -55.182  -37.084 1.00 32.04  ? 179  PRO F C     1 
ATOM   17837 O O     . PRO F 1 179 ? -63.029  -55.145  -35.924 1.00 34.46  ? 179  PRO F O     1 
ATOM   17838 C CB    . PRO F 1 179 ? -65.869  -56.019  -37.646 1.00 24.16  ? 179  PRO F CB    1 
ATOM   17839 C CG    . PRO F 1 179 ? -66.863  -55.445  -38.669 1.00 28.58  ? 179  PRO F CG    1 
ATOM   17840 C CD    . PRO F 1 179 ? -66.108  -54.407  -39.500 1.00 30.10  ? 179  PRO F CD    1 
ATOM   17841 N N     . GLU F 1 180 ? -62.652  -55.436  -38.135 1.00 34.96  ? 180  GLU F N     1 
ATOM   17842 C CA    . GLU F 1 180 ? -61.243  -55.792  -37.964 1.00 41.60  ? 180  GLU F CA    1 
ATOM   17843 C C     . GLU F 1 180 ? -60.404  -54.575  -37.572 1.00 35.39  ? 180  GLU F C     1 
ATOM   17844 O O     . GLU F 1 180 ? -59.557  -54.682  -36.685 1.00 35.91  ? 180  GLU F O     1 
ATOM   17845 C CB    . GLU F 1 180 ? -60.606  -56.595  -39.117 1.00 42.81  ? 180  GLU F CB    1 
ATOM   17846 C CG    . GLU F 1 180 ? -61.414  -57.837  -39.496 1.00 39.02  ? 180  GLU F CG    1 
ATOM   17847 C CD    . GLU F 1 180 ? -62.473  -57.680  -40.599 1.00 54.73  ? 180  GLU F CD    1 
ATOM   17848 O OE1   . GLU F 1 180 ? -63.549  -57.054  -40.512 1.00 59.73  ? 180  GLU F OE1   1 
ATOM   17849 O OE2   . GLU F 1 180 ? -62.177  -58.226  -41.671 1.00 59.06  ? 180  GLU F OE2   1 
ATOM   17850 N N     . LEU F 1 181 ? -60.624  -53.433  -38.247 1.00 33.97  ? 181  LEU F N     1 
ATOM   17851 C CA    . LEU F 1 181 ? -59.873  -52.216  -37.929 1.00 34.43  ? 181  LEU F CA    1 
ATOM   17852 C C     . LEU F 1 181 ? -60.164  -51.757  -36.491 1.00 35.42  ? 181  LEU F C     1 
ATOM   17853 O O     . LEU F 1 181 ? -59.240  -51.581  -35.690 1.00 35.80  ? 181  LEU F O     1 
ATOM   17854 C CB    . LEU F 1 181 ? -60.176  -51.118  -38.948 1.00 32.17  ? 181  LEU F CB    1 
ATOM   17855 C CG    . LEU F 1 181 ? -59.513  -49.758  -38.693 1.00 32.78  ? 181  LEU F CG    1 
ATOM   17856 C CD1   . LEU F 1 181 ? -58.003  -49.901  -38.836 1.00 33.68  ? 181  LEU F CD1   1 
ATOM   17857 C CD2   . LEU F 1 181 ? -60.041  -48.727  -39.685 1.00 30.78  ? 181  LEU F CD2   1 
ATOM   17858 N N     . TYR F 1 182 ? -61.456  -51.642  -36.141 1.00 30.08  ? 182  TYR F N     1 
ATOM   17859 C CA    . TYR F 1 182 ? -61.786  -51.087  -34.831 1.00 32.03  ? 182  TYR F CA    1 
ATOM   17860 C C     . TYR F 1 182 ? -61.547  -52.127  -33.739 1.00 36.55  ? 182  TYR F C     1 
ATOM   17861 O O     . TYR F 1 182 ? -61.201  -51.764  -32.599 1.00 36.85  ? 182  TYR F O     1 
ATOM   17862 C CB    . TYR F 1 182 ? -63.200  -50.509  -34.782 1.00 31.65  ? 182  TYR F CB    1 
ATOM   17863 C CG    . TYR F 1 182 ? -63.477  -49.398  -35.782 1.00 34.85  ? 182  TYR F CG    1 
ATOM   17864 C CD1   . TYR F 1 182 ? -62.452  -48.574  -36.264 1.00 38.17  ? 182  TYR F CD1   1 
ATOM   17865 C CD2   . TYR F 1 182 ? -64.772  -49.183  -36.251 1.00 34.46  ? 182  TYR F CD2   1 
ATOM   17866 C CE1   . TYR F 1 182 ? -62.717  -47.563  -37.179 1.00 35.86  ? 182  TYR F CE1   1 
ATOM   17867 C CE2   . TYR F 1 182 ? -65.035  -48.187  -37.183 1.00 39.42  ? 182  TYR F CE2   1 
ATOM   17868 C CZ    . TYR F 1 182 ? -64.009  -47.393  -37.666 1.00 36.68  ? 182  TYR F CZ    1 
ATOM   17869 O OH    . TYR F 1 182 ? -64.373  -46.428  -38.570 1.00 33.28  ? 182  TYR F OH    1 
ATOM   17870 N N     . GLY F 1 183 ? -61.706  -53.420  -34.098 1.00 34.30  ? 183  GLY F N     1 
ATOM   17871 C CA    . GLY F 1 183 ? -61.393  -54.510  -33.186 1.00 33.80  ? 183  GLY F CA    1 
ATOM   17872 C C     . GLY F 1 183 ? -59.918  -54.476  -32.784 1.00 36.58  ? 183  GLY F C     1 
ATOM   17873 O O     . GLY F 1 183 ? -59.589  -54.634  -31.609 1.00 35.74  ? 183  GLY F O     1 
ATOM   17874 N N     . MET F 1 184 ? -59.035  -54.228  -33.763 1.00 36.29  ? 184  MET F N     1 
ATOM   17875 C CA    . MET F 1 184 ? -57.613  -54.090  -33.490 1.00 36.49  ? 184  MET F CA    1 
ATOM   17876 C C     . MET F 1 184 ? -57.412  -52.910  -32.535 1.00 39.91  ? 184  MET F C     1 
ATOM   17877 O O     . MET F 1 184 ? -56.652  -53.015  -31.576 1.00 38.63  ? 184  MET F O     1 
ATOM   17878 C CB    . MET F 1 184 ? -56.858  -54.008  -34.832 1.00 34.69  ? 184  MET F CB    1 
ATOM   17879 C CG    . MET F 1 184 ? -55.343  -53.906  -34.815 1.00 40.38  ? 184  MET F CG    1 
ATOM   17880 S SD    . MET F 1 184 ? -54.749  -52.248  -34.461 1.00 62.13  ? 184  MET F SD    1 
ATOM   17881 C CE    . MET F 1 184 ? -55.243  -51.369  -35.933 1.00 54.25  ? 184  MET F CE    1 
ATOM   17882 N N     . ILE F 1 185 ? -58.089  -51.799  -32.773 1.00 42.39  ? 185  ILE F N     1 
ATOM   17883 C CA    . ILE F 1 185 ? -57.930  -50.655  -31.890 1.00 41.00  ? 185  ILE F CA    1 
ATOM   17884 C C     . ILE F 1 185 ? -58.376  -50.941  -30.473 1.00 38.18  ? 185  ILE F C     1 
ATOM   17885 O O     . ILE F 1 185 ? -57.710  -50.573  -29.554 1.00 35.00  ? 185  ILE F O     1 
ATOM   17886 C CB    . ILE F 1 185 ? -58.649  -49.392  -32.384 1.00 36.04  ? 185  ILE F CB    1 
ATOM   17887 C CG1   . ILE F 1 185 ? -58.074  -48.937  -33.694 1.00 31.60  ? 185  ILE F CG1   1 
ATOM   17888 C CG2   . ILE F 1 185 ? -58.496  -48.280  -31.381 1.00 31.04  ? 185  ILE F CG2   1 
ATOM   17889 C CD1   . ILE F 1 185 ? -58.889  -47.905  -34.386 1.00 31.73  ? 185  ILE F CD1   1 
ATOM   17890 N N     . ARG F 1 186 ? -59.493  -51.619  -30.304 1.00 33.29  ? 186  ARG F N     1 
ATOM   17891 C CA    . ARG F 1 186 ? -59.980  -51.942  -28.981 1.00 39.41  ? 186  ARG F CA    1 
ATOM   17892 C C     . ARG F 1 186 ? -59.050  -52.842  -28.239 1.00 44.20  ? 186  ARG F C     1 
ATOM   17893 O O     . ARG F 1 186 ? -58.910  -52.731  -27.062 1.00 48.54  ? 186  ARG F O     1 
ATOM   17894 C CB    . ARG F 1 186 ? -61.323  -52.617  -29.025 1.00 37.36  ? 186  ARG F CB    1 
ATOM   17895 C CG    . ARG F 1 186 ? -62.455  -51.704  -29.291 1.00 36.84  ? 186  ARG F CG    1 
ATOM   17896 C CD    . ARG F 1 186 ? -62.797  -50.796  -28.142 1.00 40.60  ? 186  ARG F CD    1 
ATOM   17897 N NE    . ARG F 1 186 ? -63.512  -49.675  -28.698 1.00 38.62  ? 186  ARG F NE    1 
ATOM   17898 C CZ    . ARG F 1 186 ? -63.286  -48.416  -28.416 1.00 40.86  ? 186  ARG F CZ    1 
ATOM   17899 N NH1   . ARG F 1 186 ? -62.406  -48.063  -27.519 1.00 32.88  ? 186  ARG F NH1   1 
ATOM   17900 N NH2   . ARG F 1 186 ? -63.982  -47.521  -29.030 1.00 36.61  ? 186  ARG F NH2   1 
ATOM   17901 N N     . HIS F 1 187 ? -58.462  -53.785  -28.936 1.00 43.54  ? 187  HIS F N     1 
ATOM   17902 C CA    . HIS F 1 187 ? -57.546  -54.682  -28.324 1.00 45.73  ? 187  HIS F CA    1 
ATOM   17903 C C     . HIS F 1 187 ? -56.320  -54.001  -27.757 1.00 36.39  ? 187  HIS F C     1 
ATOM   17904 O O     . HIS F 1 187 ? -55.945  -54.257  -26.656 1.00 35.21  ? 187  HIS F O     1 
ATOM   17905 C CB    . HIS F 1 187 ? -57.171  -55.708  -29.379 1.00 57.48  ? 187  HIS F CB    1 
ATOM   17906 C CG    . HIS F 1 187 ? -56.079  -56.629  -28.975 1.00 69.31  ? 187  HIS F CG    1 
ATOM   17907 N ND1   . HIS F 1 187 ? -54.906  -56.720  -29.672 1.00 67.74  ? 187  HIS F ND1   1 
ATOM   17908 C CD2   . HIS F 1 187 ? -55.982  -57.505  -27.954 1.00 70.41  ? 187  HIS F CD2   1 
ATOM   17909 C CE1   . HIS F 1 187 ? -54.123  -57.605  -29.092 1.00 68.56  ? 187  HIS F CE1   1 
ATOM   17910 N NE2   . HIS F 1 187 ? -54.753  -58.096  -28.049 1.00 81.72  ? 187  HIS F NE2   1 
ATOM   17911 N N     . TYR F 1 188 ? -55.721  -53.102  -28.501 1.00 35.27  ? 188  TYR F N     1 
ATOM   17912 C CA    . TYR F 1 188 ? -54.553  -52.398  -28.034 1.00 41.15  ? 188  TYR F CA    1 
ATOM   17913 C C     . TYR F 1 188 ? -54.793  -51.120  -27.256 1.00 40.01  ? 188  TYR F C     1 
ATOM   17914 O O     . TYR F 1 188 ? -53.985  -50.726  -26.462 1.00 35.48  ? 188  TYR F O     1 
ATOM   17915 C CB    . TYR F 1 188 ? -53.664  -52.042  -29.204 1.00 49.45  ? 188  TYR F CB    1 
ATOM   17916 C CG    . TYR F 1 188 ? -52.998  -53.189  -29.893 1.00 50.05  ? 188  TYR F CG    1 
ATOM   17917 C CD1   . TYR F 1 188 ? -51.988  -53.889  -29.296 1.00 49.71  ? 188  TYR F CD1   1 
ATOM   17918 C CD2   . TYR F 1 188 ? -53.362  -53.536  -31.155 1.00 50.05  ? 188  TYR F CD2   1 
ATOM   17919 C CE1   . TYR F 1 188 ? -51.372  -54.924  -29.944 1.00 48.37  ? 188  TYR F CE1   1 
ATOM   17920 C CE2   . TYR F 1 188 ? -52.761  -54.564  -31.802 1.00 50.93  ? 188  TYR F CE2   1 
ATOM   17921 C CZ    . TYR F 1 188 ? -51.768  -55.247  -31.194 1.00 53.54  ? 188  TYR F CZ    1 
ATOM   17922 O OH    . TYR F 1 188 ? -51.189  -56.257  -31.867 1.00 52.88  ? 188  TYR F OH    1 
ATOM   17923 N N     . GLN F 1 189 ? -55.924  -50.489  -27.510 1.00 40.20  ? 189  GLN F N     1 
ATOM   17924 C CA    . GLN F 1 189 ? -56.283  -49.198  -26.940 1.00 43.03  ? 189  GLN F CA    1 
ATOM   17925 C C     . GLN F 1 189 ? -57.733  -49.252  -26.472 1.00 47.91  ? 189  GLN F C     1 
ATOM   17926 O O     . GLN F 1 189 ? -58.583  -48.572  -27.033 1.00 43.39  ? 189  GLN F O     1 
ATOM   17927 C CB    . GLN F 1 189 ? -56.096  -48.128  -28.013 1.00 36.03  ? 189  GLN F CB    1 
ATOM   17928 C CG    . GLN F 1 189 ? -54.643  -47.884  -28.403 1.00 32.91  ? 189  GLN F CG    1 
ATOM   17929 C CD    . GLN F 1 189 ? -53.886  -47.111  -27.350 1.00 34.38  ? 189  GLN F CD    1 
ATOM   17930 O OE1   . GLN F 1 189 ? -54.487  -46.373  -26.571 1.00 36.33  ? 189  GLN F OE1   1 
ATOM   17931 N NE2   . GLN F 1 189 ? -52.564  -47.193  -27.366 1.00 30.99  ? 189  GLN F NE2   1 
ATOM   17932 N N     . PRO F 1 190 ? -58.075  -50.085  -25.454 1.00 49.25  ? 190  PRO F N     1 
ATOM   17933 C CA    . PRO F 1 190 ? -59.478  -50.292  -25.084 1.00 43.07  ? 190  PRO F CA    1 
ATOM   17934 C C     . PRO F 1 190 ? -60.210  -48.988  -24.738 1.00 42.16  ? 190  PRO F C     1 
ATOM   17935 O O     . PRO F 1 190 ? -61.416  -48.876  -24.940 1.00 39.37  ? 190  PRO F O     1 
ATOM   17936 C CB    . PRO F 1 190 ? -59.414  -51.303  -23.923 1.00 38.46  ? 190  PRO F CB    1 
ATOM   17937 C CG    . PRO F 1 190 ? -57.982  -51.138  -23.377 1.00 39.13  ? 190  PRO F CG    1 
ATOM   17938 C CD    . PRO F 1 190 ? -57.131  -50.802  -24.568 1.00 43.75  ? 190  PRO F CD    1 
ATOM   17939 N N     . ASN F 1 191 ? -59.447  -47.991  -24.273 1.00 37.41  ? 191  ASN F N     1 
ATOM   17940 C CA    . ASN F 1 191 ? -60.000  -46.753  -23.768 1.00 41.11  ? 191  ASN F CA    1 
ATOM   17941 C C     . ASN F 1 191 ? -60.051  -45.611  -24.805 1.00 36.54  ? 191  ASN F C     1 
ATOM   17942 O O     . ASN F 1 191 ? -60.504  -44.526  -24.487 1.00 33.89  ? 191  ASN F O     1 
ATOM   17943 C CB    . ASN F 1 191 ? -59.231  -46.343  -22.519 1.00 42.65  ? 191  ASN F CB    1 
ATOM   17944 C CG    . ASN F 1 191 ? -60.101  -45.444  -21.681 1.00 49.38  ? 191  ASN F CG    1 
ATOM   17945 O OD1   . ASN F 1 191 ? -61.245  -45.783  -21.346 1.00 45.87  ? 191  ASN F OD1   1 
ATOM   17946 N ND2   . ASN F 1 191 ? -59.620  -44.243  -21.440 1.00 50.57  ? 191  ASN F ND2   1 
ATOM   17947 N N     . ALA F 1 192 ? -59.577  -45.833  -26.032 1.00 34.52  ? 192  ALA F N     1 
ATOM   17948 C CA    . ALA F 1 192 ? -59.495  -44.773  -27.032 1.00 32.90  ? 192  ALA F CA    1 
ATOM   17949 C C     . ALA F 1 192 ? -60.898  -44.402  -27.511 1.00 35.88  ? 192  ALA F C     1 
ATOM   17950 O O     . ALA F 1 192 ? -61.748  -45.278  -27.670 1.00 39.68  ? 192  ALA F O     1 
ATOM   17951 C CB    . ALA F 1 192 ? -58.640  -45.252  -28.189 1.00 27.85  ? 192  ALA F CB    1 
ATOM   17952 N N     . ILE F 1 193 ? -61.140  -43.105  -27.736 1.00 33.49  ? 193  ILE F N     1 
ATOM   17953 C CA    . ILE F 1 193 ? -62.379  -42.695  -28.392 1.00 28.87  ? 193  ILE F CA    1 
ATOM   17954 C C     . ILE F 1 193 ? -62.219  -42.886  -29.904 1.00 27.27  ? 193  ILE F C     1 
ATOM   17955 O O     . ILE F 1 193 ? -61.226  -42.445  -30.480 1.00 31.69  ? 193  ILE F O     1 
ATOM   17956 C CB    . ILE F 1 193 ? -62.680  -41.225  -28.048 1.00 31.47  ? 193  ILE F CB    1 
ATOM   17957 C CG1   . ILE F 1 193 ? -63.111  -41.048  -26.579 1.00 28.07  ? 193  ILE F CG1   1 
ATOM   17958 C CG2   . ILE F 1 193 ? -63.697  -40.636  -29.025 1.00 26.29  ? 193  ILE F CG2   1 
ATOM   17959 C CD1   . ILE F 1 193 ? -64.482  -41.637  -26.275 1.00 27.24  ? 193  ILE F CD1   1 
ATOM   17960 N N     . ILE F 1 194 ? -63.158  -43.580  -30.539 1.00 24.54  ? 194  ILE F N     1 
ATOM   17961 C CA    . ILE F 1 194 ? -63.122  -43.705  -31.984 1.00 28.62  ? 194  ILE F CA    1 
ATOM   17962 C C     . ILE F 1 194 ? -64.172  -42.770  -32.595 1.00 32.76  ? 194  ILE F C     1 
ATOM   17963 O O     . ILE F 1 194 ? -65.387  -42.947  -32.378 1.00 27.63  ? 194  ILE F O     1 
ATOM   17964 C CB    . ILE F 1 194 ? -63.353  -45.159  -32.446 1.00 28.36  ? 194  ILE F CB    1 
ATOM   17965 C CG1   . ILE F 1 194 ? -62.254  -46.119  -31.937 1.00 27.66  ? 194  ILE F CG1   1 
ATOM   17966 C CG2   . ILE F 1 194 ? -63.517  -45.230  -33.974 1.00 27.54  ? 194  ILE F CG2   1 
ATOM   17967 C CD1   . ILE F 1 194 ? -62.522  -47.565  -32.331 1.00 24.23  ? 194  ILE F CD1   1 
ATOM   17968 N N     . VAL F 1 195 ? -63.696  -41.824  -33.382 1.00 28.76  ? 195  VAL F N     1 
ATOM   17969 C CA    . VAL F 1 195 ? -64.524  -40.855  -34.048 1.00 25.56  ? 195  VAL F CA    1 
ATOM   17970 C C     . VAL F 1 195 ? -64.549  -41.081  -35.537 1.00 27.30  ? 195  VAL F C     1 
ATOM   17971 O O     . VAL F 1 195 ? -63.553  -41.264  -36.146 1.00 28.75  ? 195  VAL F O     1 
ATOM   17972 C CB    . VAL F 1 195 ? -63.996  -39.444  -33.817 1.00 25.33  ? 195  VAL F CB    1 
ATOM   17973 C CG1   . VAL F 1 195 ? -64.894  -38.414  -34.442 1.00 22.50  ? 195  VAL F CG1   1 
ATOM   17974 C CG2   . VAL F 1 195 ? -63.801  -39.171  -32.363 1.00 22.00  ? 195  VAL F CG2   1 
ATOM   17975 N N     . SER F 1 196 ? -65.721  -41.045  -36.108 1.00 32.09  ? 196  SER F N     1 
ATOM   17976 C CA    . SER F 1 196 ? -65.864  -41.208  -37.530 1.00 38.62  ? 196  SER F CA    1 
ATOM   17977 C C     . SER F 1 196 ? -66.598  -40.079  -38.252 1.00 38.23  ? 196  SER F C     1 
ATOM   17978 O O     . SER F 1 196 ? -67.617  -39.614  -37.829 1.00 36.92  ? 196  SER F O     1 
ATOM   17979 C CB    . SER F 1 196 ? -66.535  -42.523  -37.843 1.00 34.03  ? 196  SER F CB    1 
ATOM   17980 O OG    . SER F 1 196 ? -66.625  -42.673  -39.203 1.00 35.42  ? 196  SER F OG    1 
ATOM   17981 N N     . ASN F 1 197 ? -66.018  -39.658  -39.350 1.00 38.61  ? 197  ASN F N     1 
ATOM   17982 C CA    . ASN F 1 197 ? -66.542  -38.626  -40.202 1.00 47.23  ? 197  ASN F CA    1 
ATOM   17983 C C     . ASN F 1 197 ? -67.646  -39.170  -41.059 1.00 49.91  ? 197  ASN F C     1 
ATOM   17984 O O     . ASN F 1 197 ? -68.471  -38.463  -41.543 1.00 58.62  ? 197  ASN F O     1 
ATOM   17985 C CB    . ASN F 1 197 ? -65.447  -38.189  -41.133 1.00 50.30  ? 197  ASN F CB    1 
ATOM   17986 C CG    . ASN F 1 197 ? -65.463  -36.728  -41.395 1.00 62.57  ? 197  ASN F CG    1 
ATOM   17987 O OD1   . ASN F 1 197 ? -66.173  -35.981  -40.746 1.00 58.87  ? 197  ASN F OD1   1 
ATOM   17988 N ND2   . ASN F 1 197 ? -64.669  -36.304  -42.349 1.00 53.62  ? 197  ASN F ND2   1 
ATOM   17989 N N     . THR F 1 198 ? -67.673  -40.458  -41.239 1.00 70.60  ? 198  THR F N     1 
ATOM   17990 C CA    . THR F 1 198 ? -68.686  -41.037  -42.067 1.00 75.70  ? 198  THR F CA    1 
ATOM   17991 C C     . THR F 1 198 ? -69.519  -42.052  -41.312 1.00 64.10  ? 198  THR F C     1 
ATOM   17992 O O     . THR F 1 198 ? -69.945  -41.797  -40.201 1.00 60.92  ? 198  THR F O     1 
ATOM   17993 C CB    . THR F 1 198 ? -68.021  -41.683  -43.272 1.00 82.75  ? 198  THR F CB    1 
ATOM   17994 O OG1   . THR F 1 198 ? -69.004  -41.981  -44.251 1.00 99.82  ? 198  THR F OG1   1 
ATOM   17995 C CG2   . THR F 1 198 ? -67.335  -42.918  -42.872 1.00 68.47  ? 198  THR F CG2   1 
ATOM   17996 N N     . GLN F 1 205 ? -78.385  -45.149  -38.423 1.00 69.55  ? 205  GLN F N     1 
ATOM   17997 C CA    . GLN F 1 205 ? -77.642  -46.363  -38.174 1.00 74.44  ? 205  GLN F CA    1 
ATOM   17998 C C     . GLN F 1 205 ? -76.180  -46.065  -38.320 1.00 75.89  ? 205  GLN F C     1 
ATOM   17999 O O     . GLN F 1 205 ? -75.741  -45.625  -39.353 1.00 67.67  ? 205  GLN F O     1 
ATOM   18000 C CB    . GLN F 1 205 ? -78.028  -47.445  -39.174 1.00 30.00  ? 205  GLN F CB    1 
ATOM   18001 C CG    . GLN F 1 205 ? -79.449  -47.950  -39.047 1.00 30.00  ? 205  GLN F CG    1 
ATOM   18002 C CD    . GLN F 1 205 ? -79.917  -48.719  -40.275 1.00 30.00  ? 205  GLN F CD    1 
ATOM   18003 O OE1   . GLN F 1 205 ? -79.869  -48.209  -41.396 1.00 30.00  ? 205  GLN F OE1   1 
ATOM   18004 N NE2   . GLN F 1 205 ? -80.383  -49.947  -40.063 1.00 30.00  ? 205  GLN F NE2   1 
ATOM   18005 N N     . VAL F 1 206 ? -75.431  -46.318  -37.268 1.00 76.07  ? 206  VAL F N     1 
ATOM   18006 C CA    . VAL F 1 206 ? -74.006  -46.083  -37.259 1.00 73.90  ? 206  VAL F CA    1 
ATOM   18007 C C     . VAL F 1 206 ? -73.266  -47.128  -38.081 1.00 65.21  ? 206  VAL F C     1 
ATOM   18008 O O     . VAL F 1 206 ? -73.747  -48.219  -38.262 1.00 58.54  ? 206  VAL F O     1 
ATOM   18009 C CB    . VAL F 1 206 ? -73.501  -46.006  -35.822 1.00 75.57  ? 206  VAL F CB    1 
ATOM   18010 C CG1   . VAL F 1 206 ? -73.356  -47.388  -35.245 1.00 70.04  ? 206  VAL F CG1   1 
ATOM   18011 C CG2   . VAL F 1 206 ? -72.225  -45.207  -35.742 1.00 66.33  ? 206  VAL F CG2   1 
ATOM   18012 N N     . SER F 1 207 ? -72.101  -46.775  -38.582 1.00 57.95  ? 207  SER F N     1 
ATOM   18013 C CA    . SER F 1 207 ? -71.334  -47.674  -39.430 1.00 61.86  ? 207  SER F CA    1 
ATOM   18014 C C     . SER F 1 207 ? -70.657  -48.847  -38.773 1.00 52.07  ? 207  SER F C     1 
ATOM   18015 O O     . SER F 1 207 ? -70.216  -49.728  -39.444 1.00 49.55  ? 207  SER F O     1 
ATOM   18016 C CB    . SER F 1 207 ? -70.323  -46.913  -40.260 1.00 56.17  ? 207  SER F CB    1 
ATOM   18017 O OG    . SER F 1 207 ? -69.270  -46.468  -39.475 1.00 59.24  ? 207  SER F OG    1 
ATOM   18018 N N     . ASP F 1 208 ? -70.557  -48.847  -37.466 1.00 46.02  ? 208  ASP F N     1 
ATOM   18019 C CA    . ASP F 1 208 ? -69.929  -49.956  -36.767 1.00 36.13  ? 208  ASP F CA    1 
ATOM   18020 C C     . ASP F 1 208 ? -70.150  -49.804  -35.268 1.00 37.93  ? 208  ASP F C     1 
ATOM   18021 O O     . ASP F 1 208 ? -70.006  -48.716  -34.728 1.00 44.82  ? 208  ASP F O     1 
ATOM   18022 C CB    . ASP F 1 208 ? -68.431  -50.063  -37.019 1.00 33.00  ? 208  ASP F CB    1 
ATOM   18023 C CG    . ASP F 1 208 ? -67.821  -51.366  -36.522 1.00 38.81  ? 208  ASP F CG    1 
ATOM   18024 O OD1   . ASP F 1 208 ? -67.848  -52.342  -37.327 1.00 38.81  ? 208  ASP F OD1   1 
ATOM   18025 O OD2   . ASP F 1 208 ? -67.398  -51.417  -35.313 1.00 31.80  ? 208  ASP F OD2   1 
ATOM   18026 N N     . PRO F 1 209 ? -70.463  -50.900  -34.537 1.00 44.98  ? 209  PRO F N     1 
ATOM   18027 C CA    . PRO F 1 209 ? -70.681  -50.835  -33.089 1.00 40.39  ? 209  PRO F CA    1 
ATOM   18028 C C     . PRO F 1 209 ? -69.547  -50.184  -32.302 1.00 38.23  ? 209  PRO F C     1 
ATOM   18029 O O     . PRO F 1 209 ? -69.779  -49.650  -31.219 1.00 38.13  ? 209  PRO F O     1 
ATOM   18030 C CB    . PRO F 1 209 ? -70.907  -52.307  -32.676 1.00 42.15  ? 209  PRO F CB    1 
ATOM   18031 C CG    . PRO F 1 209 ? -71.498  -52.884  -33.972 1.00 39.58  ? 209  PRO F CG    1 
ATOM   18032 C CD    . PRO F 1 209 ? -70.673  -52.259  -35.074 1.00 36.70  ? 209  PRO F CD    1 
ATOM   18033 N N     . GLU F 1 210 ? -68.314  -50.224  -32.835 1.00 36.52  ? 210  GLU F N     1 
ATOM   18034 C CA    . GLU F 1 210 ? -67.176  -49.736  -32.054 1.00 36.66  ? 210  GLU F CA    1 
ATOM   18035 C C     . GLU F 1 210 ? -67.024  -48.209  -32.096 1.00 32.73  ? 210  GLU F C     1 
ATOM   18036 O O     . GLU F 1 210 ? -66.251  -47.651  -31.308 1.00 31.82  ? 210  GLU F O     1 
ATOM   18037 C CB    . GLU F 1 210 ? -65.877  -50.449  -32.443 1.00 41.75  ? 210  GLU F CB    1 
ATOM   18038 C CG    . GLU F 1 210 ? -65.798  -51.871  -31.889 1.00 44.53  ? 210  GLU F CG    1 
ATOM   18039 C CD    . GLU F 1 210 ? -65.925  -51.965  -30.362 1.00 47.96  ? 210  GLU F CD    1 
ATOM   18040 O OE1   . GLU F 1 210 ? -65.712  -50.996  -29.606 1.00 40.64  ? 210  GLU F OE1   1 
ATOM   18041 O OE2   . GLU F 1 210 ? -66.281  -53.054  -29.900 1.00 52.93  ? 210  GLU F OE2   1 
ATOM   18042 N N     . ILE F 1 211 ? -67.733  -47.538  -33.019 1.00 28.65  ? 211  ILE F N     1 
ATOM   18043 C CA    . ILE F 1 211 ? -67.704  -46.084  -33.090 1.00 31.04  ? 211  ILE F CA    1 
ATOM   18044 C C     . ILE F 1 211 ? -68.279  -45.464  -31.816 1.00 27.66  ? 211  ILE F C     1 
ATOM   18045 O O     . ILE F 1 211 ? -69.318  -45.895  -31.338 1.00 33.99  ? 211  ILE F O     1 
ATOM   18046 C CB    . ILE F 1 211 ? -68.414  -45.602  -34.365 1.00 35.12  ? 211  ILE F CB    1 
ATOM   18047 C CG1   . ILE F 1 211 ? -67.507  -45.789  -35.583 1.00 36.45  ? 211  ILE F CG1   1 
ATOM   18048 C CG2   . ILE F 1 211 ? -68.834  -44.145  -34.219 1.00 39.64  ? 211  ILE F CG2   1 
ATOM   18049 C CD1   . ILE F 1 211 ? -68.292  -45.907  -36.878 1.00 44.81  ? 211  ILE F CD1   1 
ATOM   18050 N N     . ASP F 1 212 ? -67.600  -44.451  -31.272 1.00 28.96  ? 212  ASP F N     1 
ATOM   18051 C CA    . ASP F 1 212 ? -67.990  -43.764  -30.050 1.00 27.74  ? 212  ASP F CA    1 
ATOM   18052 C C     . ASP F 1 212 ? -68.576  -42.367  -30.322 1.00 30.40  ? 212  ASP F C     1 
ATOM   18053 O O     . ASP F 1 212 ? -69.372  -41.857  -29.531 1.00 34.63  ? 212  ASP F O     1 
ATOM   18054 C CB    . ASP F 1 212 ? -66.777  -43.606  -29.154 1.00 32.43  ? 212  ASP F CB    1 
ATOM   18055 C CG    . ASP F 1 212 ? -66.153  -44.918  -28.685 1.00 36.58  ? 212  ASP F CG    1 
ATOM   18056 O OD1   . ASP F 1 212 ? -66.920  -45.892  -28.423 1.00 35.18  ? 212  ASP F OD1   1 
ATOM   18057 O OD2   . ASP F 1 212 ? -64.918  -44.938  -28.526 1.00 35.65  ? 212  ASP F OD2   1 
ATOM   18058 N N     . VAL F 1 213 ? -68.151  -41.727  -31.430 1.00 26.58  ? 213  VAL F N     1 
ATOM   18059 C CA    . VAL F 1 213 ? -68.538  -40.359  -31.730 1.00 24.55  ? 213  VAL F CA    1 
ATOM   18060 C C     . VAL F 1 213 ? -68.759  -40.249  -33.235 1.00 25.92  ? 213  VAL F C     1 
ATOM   18061 O O     . VAL F 1 213 ? -67.928  -40.717  -34.024 1.00 30.29  ? 213  VAL F O     1 
ATOM   18062 C CB    . VAL F 1 213 ? -67.457  -39.338  -31.313 1.00 21.82  ? 213  VAL F CB    1 
ATOM   18063 C CG1   . VAL F 1 213 ? -67.907  -37.911  -31.622 1.00 20.39  ? 213  VAL F CG1   1 
ATOM   18064 C CG2   . VAL F 1 213 ? -67.066  -39.476  -29.852 1.00 20.47  ? 213  VAL F CG2   1 
ATOM   18065 N N     . VAL F 1 214 ? -69.844  -39.579  -33.614 1.00 25.72  ? 214  VAL F N     1 
ATOM   18066 C CA    . VAL F 1 214 ? -70.092  -39.228  -35.008 1.00 31.58  ? 214  VAL F CA    1 
ATOM   18067 C C     . VAL F 1 214 ? -69.987  -37.707  -35.172 1.00 28.50  ? 214  VAL F C     1 
ATOM   18068 O O     . VAL F 1 214 ? -70.306  -36.970  -34.241 1.00 27.33  ? 214  VAL F O     1 
ATOM   18069 C CB    . VAL F 1 214 ? -71.518  -39.780  -35.219 1.00 34.08  ? 214  VAL F CB    1 
ATOM   18070 C CG1   . VAL F 1 214 ? -72.235  -39.122  -36.374 1.00 37.83  ? 214  VAL F CG1   1 
ATOM   18071 C CG2   . VAL F 1 214 ? -71.431  -41.267  -35.534 1.00 39.23  ? 214  VAL F CG2   1 
ATOM   18072 N N     . THR F 1 215 ? -69.524  -37.244  -36.336 1.00 29.42  ? 215  THR F N     1 
ATOM   18073 C CA    . THR F 1 215 ? -69.491  -35.809  -36.636 1.00 37.44  ? 215  THR F CA    1 
ATOM   18074 C C     . THR F 1 215 ? -70.781  -35.317  -37.311 1.00 46.84  ? 215  THR F C     1 
ATOM   18075 O O     . THR F 1 215 ? -71.524  -36.078  -37.924 1.00 56.38  ? 215  THR F O     1 
ATOM   18076 C CB    . THR F 1 215 ? -68.280  -35.478  -37.492 1.00 35.26  ? 215  THR F CB    1 
ATOM   18077 O OG1   . THR F 1 215 ? -68.646  -36.169  -38.686 1.00 33.70  ? 215  THR F OG1   1 
ATOM   18078 C CG2   . THR F 1 215 ? -66.983  -35.951  -36.855 1.00 26.67  ? 215  THR F CG2   1 
ATOM   18079 N N     . TYR F 1 216 ? -71.071  -34.028  -37.159 1.00 47.40  ? 216  TYR F N     1 
ATOM   18080 C CA    . TYR F 1 216 ? -72.270  -33.409  -37.708 1.00 45.40  ? 216  TYR F CA    1 
ATOM   18081 C C     . TYR F 1 216 ? -71.911  -32.032  -38.264 1.00 49.08  ? 216  TYR F C     1 
ATOM   18082 O O     . TYR F 1 216 ? -70.854  -31.498  -37.901 1.00 48.52  ? 216  TYR F O     1 
ATOM   18083 C CB    . TYR F 1 216 ? -73.258  -33.156  -36.568 1.00 43.50  ? 216  TYR F CB    1 
ATOM   18084 C CG    . TYR F 1 216 ? -73.857  -34.401  -35.959 1.00 48.85  ? 216  TYR F CG    1 
ATOM   18085 C CD1   . TYR F 1 216 ? -73.210  -35.086  -34.936 1.00 44.67  ? 216  TYR F CD1   1 
ATOM   18086 C CD2   . TYR F 1 216 ? -75.074  -34.895  -36.435 1.00 49.61  ? 216  TYR F CD2   1 
ATOM   18087 C CE1   . TYR F 1 216 ? -73.757  -36.242  -34.403 1.00 43.88  ? 216  TYR F CE1   1 
ATOM   18088 C CE2   . TYR F 1 216 ? -75.632  -36.047  -35.909 1.00 50.58  ? 216  TYR F CE2   1 
ATOM   18089 C CZ    . TYR F 1 216 ? -74.965  -36.719  -34.893 1.00 54.39  ? 216  TYR F CZ    1 
ATOM   18090 O OH    . TYR F 1 216 ? -75.522  -37.853  -34.380 1.00 57.51  ? 216  TYR F OH    1 
ATOM   18091 N N     . GLU F 1 217 ? -72.813  -31.474  -39.108 1.00 54.13  ? 217  GLU F N     1 
ATOM   18092 C CA    . GLU F 1 217 ? -72.708  -30.126  -39.666 1.00 56.51  ? 217  GLU F CA    1 
ATOM   18093 C C     . GLU F 1 217 ? -72.862  -29.083  -38.560 1.00 47.76  ? 217  GLU F C     1 
ATOM   18094 O O     . GLU F 1 217 ? -73.709  -29.231  -37.676 1.00 47.96  ? 217  GLU F O     1 
ATOM   18095 C CB    . GLU F 1 217 ? -73.755  -29.833  -40.744 1.00 61.39  ? 217  GLU F CB    1 
ATOM   18096 C CG    . GLU F 1 217 ? -73.394  -30.418  -42.104 1.00 79.26  ? 217  GLU F CG    1 
ATOM   18097 C CD    . GLU F 1 217 ? -74.583  -30.238  -43.036 1.00 97.26  ? 217  GLU F CD    1 
ATOM   18098 O OE1   . GLU F 1 217 ? -75.518  -29.489  -42.668 1.00 102.45 ? 217  GLU F OE1   1 
ATOM   18099 O OE2   . GLU F 1 217 ? -74.593  -30.868  -44.110 1.00 95.47  ? 217  GLU F OE2   1 
ATOM   18100 N N     . ARG F 1 218 ? -72.059  -28.016  -38.629 1.00 45.43  ? 218  ARG F N     1 
ATOM   18101 C CA    . ARG F 1 218 ? -72.006  -27.068  -37.526 1.00 53.61  ? 218  ARG F CA    1 
ATOM   18102 C C     . ARG F 1 218 ? -73.350  -26.364  -37.354 1.00 53.70  ? 218  ARG F C     1 
ATOM   18103 O O     . ARG F 1 218 ? -73.682  -25.918  -36.255 1.00 43.52  ? 218  ARG F O     1 
ATOM   18104 C CB    . ARG F 1 218 ? -70.783  -26.150  -37.549 1.00 53.99  ? 218  ARG F CB    1 
ATOM   18105 C CG    . ARG F 1 218 ? -70.793  -25.114  -38.658 1.00 54.58  ? 218  ARG F CG    1 
ATOM   18106 C CD    . ARG F 1 218 ? -69.450  -24.411  -38.648 1.00 52.47  ? 218  ARG F CD    1 
ATOM   18107 N NE    . ARG F 1 218 ? -69.638  -23.039  -39.147 1.00 62.78  ? 218  ARG F NE    1 
ATOM   18108 C CZ    . ARG F 1 218 ? -69.693  -22.760  -40.435 1.00 63.61  ? 218  ARG F CZ    1 
ATOM   18109 N NH1   . ARG F 1 218 ? -69.468  -23.715  -41.325 1.00 65.74  ? 218  ARG F NH1   1 
ATOM   18110 N NH2   . ARG F 1 218 ? -69.986  -21.545  -40.857 1.00 66.23  ? 218  ARG F NH2   1 
ATOM   18111 N N     . ARG F 1 219 ? -74.151  -26.364  -38.426 1.00 66.93  ? 219  ARG F N     1 
ATOM   18112 C CA    . ARG F 1 219 ? -75.420  -25.659  -38.406 1.00 73.98  ? 219  ARG F CA    1 
ATOM   18113 C C     . ARG F 1 219 ? -76.568  -26.544  -37.904 1.00 71.94  ? 219  ARG F C     1 
ATOM   18114 O O     . ARG F 1 219 ? -77.685  -26.033  -37.841 1.00 65.18  ? 219  ARG F O     1 
ATOM   18115 C CB    . ARG F 1 219 ? -75.689  -24.992  -39.761 1.00 74.49  ? 219  ARG F CB    1 
ATOM   18116 C CG    . ARG F 1 219 ? -74.873  -23.718  -39.929 1.00 82.84  ? 219  ARG F CG    1 
ATOM   18117 C CD    . ARG F 1 219 ? -74.979  -23.193  -41.358 1.00 92.89  ? 219  ARG F CD    1 
ATOM   18118 N NE    . ARG F 1 219 ? -73.761  -23.375  -42.161 1.00 88.37  ? 219  ARG F NE    1 
ATOM   18119 C CZ    . ARG F 1 219 ? -73.040  -22.389  -42.718 1.00 100.94 ? 219  ARG F CZ    1 
ATOM   18120 N NH1   . ARG F 1 219 ? -73.448  -21.125  -42.649 1.00 105.97 ? 219  ARG F NH1   1 
ATOM   18121 N NH2   . ARG F 1 219 ? -71.901  -22.674  -43.338 1.00 95.21  ? 219  ARG F NH2   1 
ATOM   18122 N N     . THR F 1 220 ? -76.307  -27.814  -37.528 1.00 54.23  ? 220  THR F N     1 
ATOM   18123 C CA    . THR F 1 220 ? -77.372  -28.680  -37.033 1.00 65.12  ? 220  THR F CA    1 
ATOM   18124 C C     . THR F 1 220 ? -78.243  -27.894  -36.042 1.00 63.64  ? 220  THR F C     1 
ATOM   18125 O O     . THR F 1 220 ? -77.730  -27.398  -35.039 1.00 46.96  ? 220  THR F O     1 
ATOM   18126 C CB    . THR F 1 220 ? -76.830  -29.953  -36.377 1.00 56.77  ? 220  THR F CB    1 
ATOM   18127 O OG1   . THR F 1 220 ? -75.926  -30.580  -37.273 1.00 50.42  ? 220  THR F OG1   1 
ATOM   18128 C CG2   . THR F 1 220 ? -77.944  -30.909  -35.992 1.00 62.96  ? 220  THR F CG2   1 
ATOM   18129 N N     . PRO F 1 221 ? -79.576  -27.743  -36.280 1.00 79.73  ? 221  PRO F N     1 
ATOM   18130 C CA    . PRO F 1 221 ? -80.405  -26.874  -35.438 1.00 77.16  ? 221  PRO F CA    1 
ATOM   18131 C C     . PRO F 1 221 ? -80.742  -27.446  -34.057 1.00 71.28  ? 221  PRO F C     1 
ATOM   18132 O O     . PRO F 1 221 ? -80.813  -26.699  -33.084 1.00 56.12  ? 221  PRO F O     1 
ATOM   18133 C CB    . PRO F 1 221 ? -81.607  -26.506  -36.327 1.00 67.24  ? 221  PRO F CB    1 
ATOM   18134 C CG    . PRO F 1 221 ? -81.676  -27.648  -37.342 1.00 76.94  ? 221  PRO F CG    1 
ATOM   18135 C CD    . PRO F 1 221 ? -80.337  -28.364  -37.386 1.00 88.61  ? 221  PRO F CD    1 
ATOM   18136 N N     . ASP F 1 222 ? -80.925  -28.775  -33.977 1.00 71.54  ? 222  ASP F N     1 
ATOM   18137 C CA    . ASP F 1 222 ? -81.484  -29.397  -32.785 1.00 77.84  ? 222  ASP F CA    1 
ATOM   18138 C C     . ASP F 1 222 ? -80.473  -30.350  -32.168 1.00 67.44  ? 222  ASP F C     1 
ATOM   18139 O O     . ASP F 1 222 ? -79.530  -30.770  -32.838 1.00 68.74  ? 222  ASP F O     1 
ATOM   18140 C CB    . ASP F 1 222 ? -82.719  -30.236  -33.092 1.00 94.00  ? 222  ASP F CB    1 
ATOM   18141 C CG    . ASP F 1 222 ? -83.823  -29.537  -33.869 1.00 93.07  ? 222  ASP F CG    1 
ATOM   18142 O OD1   . ASP F 1 222 ? -84.371  -28.538  -33.343 1.00 93.87  ? 222  ASP F OD1   1 
ATOM   18143 O OD2   . ASP F 1 222 ? -84.103  -29.992  -34.999 1.00 90.65  ? 222  ASP F OD2   1 
ATOM   18144 N N     . GLU F 1 223 ? -80.740  -30.719  -30.905 1.00 68.30  ? 223  GLU F N     1 
ATOM   18145 C CA    . GLU F 1 223 ? -79.980  -31.719  -30.168 1.00 74.37  ? 223  GLU F CA    1 
ATOM   18146 C C     . GLU F 1 223 ? -79.676  -32.942  -31.047 1.00 69.03  ? 223  GLU F C     1 
ATOM   18147 O O     . GLU F 1 223 ? -80.541  -33.424  -31.769 1.00 78.67  ? 223  GLU F O     1 
ATOM   18148 C CB    . GLU F 1 223 ? -80.730  -32.046  -28.875 1.00 73.82  ? 223  GLU F CB    1 
ATOM   18149 C CG    . GLU F 1 223 ? -79.941  -33.019  -28.002 1.00 88.72  ? 223  GLU F CG    1 
ATOM   18150 C CD    . GLU F 1 223 ? -80.462  -33.180  -26.581 1.00 90.04  ? 223  GLU F CD    1 
ATOM   18151 O OE1   . GLU F 1 223 ? -81.509  -32.553  -26.240 1.00 63.01  ? 223  GLU F OE1   1 
ATOM   18152 O OE2   . GLU F 1 223 ? -79.798  -33.947  -25.832 1.00 86.04  ? 223  GLU F OE2   1 
ATOM   18153 N N     . ILE F 1 224 ? -78.427  -33.426  -31.006 1.00 66.62  ? 224  ILE F N     1 
ATOM   18154 C CA    . ILE F 1 224 ? -77.955  -34.437  -31.949 1.00 60.95  ? 224  ILE F CA    1 
ATOM   18155 C C     . ILE F 1 224 ? -78.505  -35.818  -31.556 1.00 68.47  ? 224  ILE F C     1 
ATOM   18156 O O     . ILE F 1 224 ? -79.031  -36.004  -30.446 1.00 59.56  ? 224  ILE F O     1 
ATOM   18157 C CB    . ILE F 1 224 ? -76.415  -34.463  -31.998 1.00 47.36  ? 224  ILE F CB    1 
ATOM   18158 C CG1   . ILE F 1 224 ? -75.872  -34.721  -30.631 1.00 43.19  ? 224  ILE F CG1   1 
ATOM   18159 C CG2   . ILE F 1 224 ? -75.824  -33.184  -32.584 1.00 45.13  ? 224  ILE F CG2   1 
ATOM   18160 C CD1   . ILE F 1 224 ? -74.614  -35.552  -30.646 1.00 54.34  ? 224  ILE F CD1   1 
ATOM   18161 N N     . TYR F 1 225 ? -78.325  -36.790  -32.466 1.00 70.42  ? 225  TYR F N     1 
ATOM   18162 C CA    . TYR F 1 225 ? -78.811  -38.157  -32.307 1.00 82.42  ? 225  TYR F CA    1 
ATOM   18163 C C     . TYR F 1 225 ? -77.806  -39.026  -31.540 1.00 65.99  ? 225  TYR F C     1 
ATOM   18164 O O     . TYR F 1 225 ? -76.625  -39.074  -31.876 1.00 65.33  ? 225  TYR F O     1 
ATOM   18165 C CB    . TYR F 1 225 ? -79.001  -38.654  -33.746 1.00 106.63 ? 225  TYR F CB    1 
ATOM   18166 C CG    . TYR F 1 225 ? -79.337  -40.135  -33.873 1.00 128.59 ? 225  TYR F CG    1 
ATOM   18167 C CD1   . TYR F 1 225 ? -80.540  -40.638  -33.363 1.00 121.80 ? 225  TYR F CD1   1 
ATOM   18168 C CD2   . TYR F 1 225 ? -78.458  -41.022  -34.503 1.00 111.38 ? 225  TYR F CD2   1 
ATOM   18169 C CE1   . TYR F 1 225 ? -80.850  -41.987  -33.466 1.00 128.44 ? 225  TYR F CE1   1 
ATOM   18170 C CE2   . TYR F 1 225 ? -78.764  -42.371  -34.618 1.00 120.41 ? 225  TYR F CE2   1 
ATOM   18171 C CZ    . TYR F 1 225 ? -79.963  -42.849  -34.102 1.00 142.22 ? 225  TYR F CZ    1 
ATOM   18172 O OH    . TYR F 1 225 ? -80.258  -44.183  -34.207 1.00 139.30 ? 225  TYR F OH    1 
ATOM   18173 N N     . HIS F 1 226 ? -78.275  -39.777  -30.543 1.00 59.05  ? 226  HIS F N     1 
ATOM   18174 C CA    . HIS F 1 226 ? -77.365  -40.543  -29.701 1.00 56.46  ? 226  HIS F CA    1 
ATOM   18175 C C     . HIS F 1 226 ? -77.407  -42.063  -29.924 1.00 62.66  ? 226  HIS F C     1 
ATOM   18176 O O     . HIS F 1 226 ? -76.755  -42.791  -29.179 1.00 60.61  ? 226  HIS F O     1 
ATOM   18177 C CB    . HIS F 1 226 ? -77.569  -40.142  -28.239 1.00 54.10  ? 226  HIS F CB    1 
ATOM   18178 C CG    . HIS F 1 226 ? -77.139  -38.750  -27.971 1.00 58.98  ? 226  HIS F CG    1 
ATOM   18179 N ND1   . HIS F 1 226 ? -75.861  -38.307  -28.244 1.00 61.89  ? 226  HIS F ND1   1 
ATOM   18180 C CD2   . HIS F 1 226 ? -77.786  -37.709  -27.441 1.00 66.95  ? 226  HIS F CD2   1 
ATOM   18181 C CE1   . HIS F 1 226 ? -75.752  -37.032  -27.899 1.00 60.98  ? 226  HIS F CE1   1 
ATOM   18182 N NE2   . HIS F 1 226 ? -76.912  -36.649  -27.408 1.00 69.78  ? 226  HIS F NE2   1 
ATOM   18183 N N     . GLY F 1 227 ? -78.139  -42.542  -30.946 1.00 80.06  ? 227  GLY F N     1 
ATOM   18184 C CA    . GLY F 1 227 ? -78.342  -43.966  -31.204 1.00 91.92  ? 227  GLY F CA    1 
ATOM   18185 C C     . GLY F 1 227 ? -79.772  -44.430  -30.893 1.00 102.12 ? 227  GLY F C     1 
ATOM   18186 O O     . GLY F 1 227 ? -80.494  -43.769  -30.147 1.00 83.44  ? 227  GLY F O     1 
ATOM   18187 N N     . ALA F 1 228 ? -80.172  -45.593  -31.455 1.00 121.07 ? 228  ALA F N     1 
ATOM   18188 C CA    . ALA F 1 228 ? -81.453  -46.246  -31.187 1.00 124.99 ? 228  ALA F CA    1 
ATOM   18189 C C     . ALA F 1 228 ? -81.510  -46.633  -29.704 1.00 142.93 ? 228  ALA F C     1 
ATOM   18190 O O     . ALA F 1 228 ? -80.464  -46.895  -29.116 1.00 169.35 ? 228  ALA F O     1 
ATOM   18191 C CB    . ALA F 1 228 ? -81.580  -47.454  -32.091 1.00 97.44  ? 228  ALA F CB    1 
ATOM   18192 N N     . PRO F 1 229 ? -82.679  -46.675  -29.019 1.00 151.89 ? 229  PRO F N     1 
ATOM   18193 C CA    . PRO F 1 229 ? -82.686  -46.527  -27.560 1.00 152.81 ? 229  PRO F CA    1 
ATOM   18194 C C     . PRO F 1 229 ? -81.990  -47.623  -26.755 1.00 158.78 ? 229  PRO F C     1 
ATOM   18195 O O     . PRO F 1 229 ? -81.262  -47.291  -25.820 1.00 136.97 ? 229  PRO F O     1 
ATOM   18196 C CB    . PRO F 1 229 ? -84.103  -46.081  -27.194 1.00 134.57 ? 229  PRO F CB    1 
ATOM   18197 C CG    . PRO F 1 229 ? -84.923  -46.549  -28.390 1.00 134.85 ? 229  PRO F CG    1 
ATOM   18198 C CD    . PRO F 1 229 ? -84.028  -46.841  -29.577 1.00 132.15 ? 229  PRO F CD    1 
ATOM   18199 N N     . ASN F 1 230 ? -82.185  -48.899  -27.091 1.00 154.01 ? 230  ASN F N     1 
ATOM   18200 C CA    . ASN F 1 230 ? -81.558  -49.975  -26.329 1.00 118.03 ? 230  ASN F CA    1 
ATOM   18201 C C     . ASN F 1 230 ? -80.157  -50.308  -26.852 1.00 101.76 ? 230  ASN F C     1 
ATOM   18202 O O     . ASN F 1 230 ? -79.601  -51.364  -26.563 1.00 87.16  ? 230  ASN F O     1 
ATOM   18203 C CB    . ASN F 1 230 ? -82.513  -51.157  -26.321 1.00 114.82 ? 230  ASN F CB    1 
ATOM   18204 C CG    . ASN F 1 230 ? -83.259  -51.243  -27.633 1.00 125.22 ? 230  ASN F CG    1 
ATOM   18205 O OD1   . ASN F 1 230 ? -82.799  -50.719  -28.662 1.00 115.45 ? 230  ASN F OD1   1 
ATOM   18206 N ND2   . ASN F 1 230 ? -84.393  -51.930  -27.620 1.00 105.59 ? 230  ASN F ND2   1 
ATOM   18207 N N     . GLU F 1 231 ? -79.572  -49.433  -27.670 1.00 107.08 ? 231  GLU F N     1 
ATOM   18208 C CA    . GLU F 1 231 ? -78.266  -49.640  -28.287 1.00 80.57  ? 231  GLU F CA    1 
ATOM   18209 C C     . GLU F 1 231 ? -77.204  -48.739  -27.656 1.00 60.00  ? 231  GLU F C     1 
ATOM   18210 O O     . GLU F 1 231 ? -77.501  -47.999  -26.712 1.00 57.87  ? 231  GLU F O     1 
ATOM   18211 C CB    . GLU F 1 231 ? -78.426  -49.495  -29.796 1.00 86.74  ? 231  GLU F CB    1 
ATOM   18212 C CG    . GLU F 1 231 ? -79.412  -50.515  -30.350 1.00 107.56 ? 231  GLU F CG    1 
ATOM   18213 C CD    . GLU F 1 231 ? -79.234  -50.721  -31.848 1.00 115.88 ? 231  GLU F CD    1 
ATOM   18214 O OE1   . GLU F 1 231 ? -79.859  -51.663  -32.379 1.00 117.81 ? 231  GLU F OE1   1 
ATOM   18215 O OE2   . GLU F 1 231 ? -78.472  -49.965  -32.493 1.00 101.39 ? 231  GLU F OE2   1 
ATOM   18216 N N     . LYS F 1 232 ? -75.953  -48.844  -28.125 1.00 52.70  ? 232  LYS F N     1 
ATOM   18217 C CA    . LYS F 1 232 ? -74.849  -48.074  -27.570 1.00 44.43  ? 232  LYS F CA    1 
ATOM   18218 C C     . LYS F 1 232 ? -75.135  -46.580  -27.762 1.00 43.06  ? 232  LYS F C     1 
ATOM   18219 O O     . LYS F 1 232 ? -75.521  -46.165  -28.854 1.00 35.76  ? 232  LYS F O     1 
ATOM   18220 C CB    . LYS F 1 232 ? -73.582  -48.461  -28.332 1.00 34.37  ? 232  LYS F CB    1 
ATOM   18221 C CG    . LYS F 1 232 ? -72.318  -47.909  -27.697 1.00 39.13  ? 232  LYS F CG    1 
ATOM   18222 C CD    . LYS F 1 232 ? -71.151  -48.039  -28.660 1.00 36.25  ? 232  LYS F CD    1 
ATOM   18223 C CE    . LYS F 1 232 ? -69.883  -47.430  -28.152 1.00 38.30  ? 232  LYS F CE    1 
ATOM   18224 N NZ    . LYS F 1 232 ? -68.805  -47.612  -29.130 1.00 34.97  ? 232  LYS F NZ    1 
ATOM   18225 N N     . TYR F 1 233 ? -74.962  -45.785  -26.700 1.00 34.14  ? 233  TYR F N     1 
ATOM   18226 C CA    . TYR F 1 233 ? -74.999  -44.340  -26.830 1.00 37.99  ? 233  TYR F CA    1 
ATOM   18227 C C     . TYR F 1 233 ? -73.746  -43.836  -27.565 1.00 37.25  ? 233  TYR F C     1 
ATOM   18228 O O     . TYR F 1 233 ? -72.623  -44.139  -27.143 1.00 35.68  ? 233  TYR F O     1 
ATOM   18229 C CB    . TYR F 1 233 ? -74.977  -43.786  -25.403 1.00 38.81  ? 233  TYR F CB    1 
ATOM   18230 C CG    . TYR F 1 233 ? -74.977  -42.264  -25.324 1.00 44.36  ? 233  TYR F CG    1 
ATOM   18231 C CD1   . TYR F 1 233 ? -73.789  -41.525  -25.474 1.00 41.43  ? 233  TYR F CD1   1 
ATOM   18232 C CD2   . TYR F 1 233 ? -76.159  -41.557  -25.086 1.00 40.65  ? 233  TYR F CD2   1 
ATOM   18233 C CE1   . TYR F 1 233 ? -73.772  -40.134  -25.368 1.00 41.25  ? 233  TYR F CE1   1 
ATOM   18234 C CE2   . TYR F 1 233 ? -76.152  -40.164  -24.980 1.00 47.15  ? 233  TYR F CE2   1 
ATOM   18235 C CZ    . TYR F 1 233 ? -74.957  -39.458  -25.116 1.00 44.98  ? 233  TYR F CZ    1 
ATOM   18236 O OH    . TYR F 1 233 ? -74.946  -38.112  -25.019 1.00 36.38  ? 233  TYR F OH    1 
ATOM   18237 N N     . VAL F 1 234 ? -73.952  -43.016  -28.604 1.00 31.80  ? 234  VAL F N     1 
ATOM   18238 C CA    . VAL F 1 234 ? -72.841  -42.433  -29.339 1.00 31.46  ? 234  VAL F CA    1 
ATOM   18239 C C     . VAL F 1 234 ? -72.896  -40.908  -29.182 1.00 33.17  ? 234  VAL F C     1 
ATOM   18240 O O     . VAL F 1 234 ? -73.952  -40.297  -29.325 1.00 30.85  ? 234  VAL F O     1 
ATOM   18241 C CB    . VAL F 1 234 ? -72.693  -42.876  -30.807 1.00 33.92  ? 234  VAL F CB    1 
ATOM   18242 C CG1   . VAL F 1 234 ? -72.902  -44.378  -30.974 1.00 33.65  ? 234  VAL F CG1   1 
ATOM   18243 C CG2   . VAL F 1 234 ? -73.618  -42.128  -31.737 1.00 38.14  ? 234  VAL F CG2   1 
ATOM   18244 N N     . ALA F 1 235 ? -71.747  -40.292  -28.867 1.00 27.61  ? 235  ALA F N     1 
ATOM   18245 C CA    . ALA F 1 235 ? -71.661  -38.853  -28.752 1.00 25.21  ? 235  ALA F CA    1 
ATOM   18246 C C     . ALA F 1 235 ? -71.585  -38.198  -30.141 1.00 26.86  ? 235  ALA F C     1 
ATOM   18247 O O     . ALA F 1 235 ? -71.553  -38.890  -31.171 1.00 24.54  ? 235  ALA F O     1 
ATOM   18248 C CB    . ALA F 1 235 ? -70.447  -38.521  -27.915 1.00 24.04  ? 235  ALA F CB    1 
ATOM   18249 N N     . GLY F 1 236 ? -71.532  -36.851  -30.159 1.00 24.97  ? 236  GLY F N     1 
ATOM   18250 C CA    . GLY F 1 236 ? -71.437  -36.102  -31.410 1.00 23.13  ? 236  GLY F CA    1 
ATOM   18251 C C     . GLY F 1 236 ? -70.434  -34.955  -31.312 1.00 22.19  ? 236  GLY F C     1 
ATOM   18252 O O     . GLY F 1 236 ? -70.091  -34.495  -30.215 1.00 21.03  ? 236  GLY F O     1 
ATOM   18253 N N     . GLU F 1 237 ? -69.936  -34.506  -32.475 1.00 22.96  ? 237  GLU F N     1 
ATOM   18254 C CA    . GLU F 1 237 ? -68.938  -33.444  -32.517 1.00 21.24  ? 237  GLU F CA    1 
ATOM   18255 C C     . GLU F 1 237 ? -69.157  -32.620  -33.778 1.00 21.74  ? 237  GLU F C     1 
ATOM   18256 O O     . GLU F 1 237 ? -69.483  -33.180  -34.832 1.00 24.26  ? 237  GLU F O     1 
ATOM   18257 C CB    . GLU F 1 237 ? -67.572  -34.100  -32.583 1.00 20.63  ? 237  GLU F CB    1 
ATOM   18258 C CG    . GLU F 1 237 ? -66.383  -33.162  -32.375 1.00 23.07  ? 237  GLU F CG    1 
ATOM   18259 C CD    . GLU F 1 237 ? -65.058  -33.912  -32.640 1.00 27.96  ? 237  GLU F CD    1 
ATOM   18260 O OE1   . GLU F 1 237 ? -64.267  -34.221  -31.684 1.00 31.14  ? 237  GLU F OE1   1 
ATOM   18261 O OE2   . GLU F 1 237 ? -64.803  -34.201  -33.848 1.00 27.73  ? 237  GLU F OE2   1 
ATOM   18262 N N     . ILE F 1 238 ? -69.018  -31.296  -33.665 1.00 21.58  ? 238  ILE F N     1 
ATOM   18263 C CA    . ILE F 1 238 ? -68.982  -30.437  -34.843 1.00 23.76  ? 238  ILE F CA    1 
ATOM   18264 C C     . ILE F 1 238 ? -67.597  -29.790  -34.956 1.00 24.27  ? 238  ILE F C     1 
ATOM   18265 O O     . ILE F 1 238 ? -66.833  -29.764  -33.990 1.00 29.66  ? 238  ILE F O     1 
ATOM   18266 C CB    . ILE F 1 238 ? -70.136  -29.415  -34.832 1.00 26.81  ? 238  ILE F CB    1 
ATOM   18267 C CG1   . ILE F 1 238 ? -69.946  -28.345  -33.795 1.00 30.20  ? 238  ILE F CG1   1 
ATOM   18268 C CG2   . ILE F 1 238 ? -71.499  -30.091  -34.660 1.00 24.85  ? 238  ILE F CG2   1 
ATOM   18269 C CD1   . ILE F 1 238 ? -71.110  -27.378  -33.723 1.00 29.91  ? 238  ILE F CD1   1 
ATOM   18270 N N     . SER F 1 239 ? -67.307  -29.226  -36.118 1.00 24.80  ? 239  SER F N     1 
ATOM   18271 C CA    . SER F 1 239 ? -66.013  -28.662  -36.478 1.00 28.53  ? 239  SER F CA    1 
ATOM   18272 C C     . SER F 1 239 ? -66.195  -27.292  -37.106 1.00 27.01  ? 239  SER F C     1 
ATOM   18273 O O     . SER F 1 239 ? -67.107  -27.098  -37.884 1.00 28.21  ? 239  SER F O     1 
ATOM   18274 C CB    . SER F 1 239 ? -65.345  -29.539  -37.514 1.00 32.18  ? 239  SER F CB    1 
ATOM   18275 O OG    . SER F 1 239 ? -64.676  -30.580  -36.839 1.00 47.31  ? 239  SER F OG    1 
ATOM   18276 N N     . ILE F 1 240 ? -65.275  -26.373  -36.831 1.00 28.21  ? 240  ILE F N     1 
ATOM   18277 C CA    . ILE F 1 240 ? -65.271  -25.115  -37.552 1.00 26.15  ? 240  ILE F CA    1 
ATOM   18278 C C     . ILE F 1 240 ? -63.825  -24.835  -37.962 1.00 26.65  ? 240  ILE F C     1 
ATOM   18279 O O     . ILE F 1 240 ? -62.893  -25.028  -37.182 1.00 26.42  ? 240  ILE F O     1 
ATOM   18280 C CB    . ILE F 1 240 ? -65.893  -23.999  -36.683 1.00 27.69  ? 240  ILE F CB    1 
ATOM   18281 C CG1   . ILE F 1 240 ? -66.040  -22.703  -37.455 1.00 32.10  ? 240  ILE F CG1   1 
ATOM   18282 C CG2   . ILE F 1 240 ? -65.125  -23.726  -35.384 1.00 22.61  ? 240  ILE F CG2   1 
ATOM   18283 C CD1   . ILE F 1 240 ? -66.686  -21.566  -36.674 1.00 38.67  ? 240  ILE F CD1   1 
ATOM   18284 N N     . THR F 1 241 ? -63.646  -24.399  -39.208 1.00 25.63  ? 241  THR F N     1 
ATOM   18285 C CA    . THR F 1 241 ? -62.360  -23.866  -39.613 1.00 26.46  ? 241  THR F CA    1 
ATOM   18286 C C     . THR F 1 241 ? -62.490  -22.342  -39.717 1.00 23.67  ? 241  THR F C     1 
ATOM   18287 O O     . THR F 1 241 ? -63.578  -21.824  -39.893 1.00 25.33  ? 241  THR F O     1 
ATOM   18288 C CB    . THR F 1 241 ? -61.869  -24.585  -40.886 1.00 29.61  ? 241  THR F CB    1 
ATOM   18289 O OG1   . THR F 1 241 ? -60.484  -24.211  -40.997 1.00 32.07  ? 241  THR F OG1   1 
ATOM   18290 C CG2   . THR F 1 241 ? -62.733  -24.250  -42.088 1.00 23.92  ? 241  THR F CG2   1 
ATOM   18291 N N     . LEU F 1 242 ? -61.384  -21.610  -39.589 1.00 23.42  ? 242  LEU F N     1 
ATOM   18292 C CA    . LEU F 1 242 ? -61.446  -20.155  -39.458 1.00 24.77  ? 242  LEU F CA    1 
ATOM   18293 C C     . LEU F 1 242 ? -61.763  -19.471  -40.788 1.00 25.61  ? 242  LEU F C     1 
ATOM   18294 O O     . LEU F 1 242 ? -62.475  -18.457  -40.803 1.00 26.37  ? 242  LEU F O     1 
ATOM   18295 C CB    . LEU F 1 242 ? -60.147  -19.616  -38.865 1.00 25.87  ? 242  LEU F CB    1 
ATOM   18296 C CG    . LEU F 1 242 ? -59.794  -20.152  -37.469 1.00 25.97  ? 242  LEU F CG    1 
ATOM   18297 C CD1   . LEU F 1 242 ? -58.418  -19.572  -37.057 1.00 23.22  ? 242  LEU F CD1   1 
ATOM   18298 C CD2   . LEU F 1 242 ? -60.900  -19.953  -36.416 1.00 21.49  ? 242  LEU F CD2   1 
ATOM   18299 N N     . ASN F 1 243 ? -61.221  -20.002  -41.897 1.00 22.81  ? 243  ASN F N     1 
ATOM   18300 C CA    . ASN F 1 243 ? -61.581  -19.503  -43.217 1.00 23.61  ? 243  ASN F CA    1 
ATOM   18301 C C     . ASN F 1 243 ? -62.275  -20.650  -43.957 1.00 22.91  ? 243  ASN F C     1 
ATOM   18302 O O     . ASN F 1 243 ? -63.020  -21.395  -43.338 1.00 22.23  ? 243  ASN F O     1 
ATOM   18303 C CB    . ASN F 1 243 ? -60.418  -18.787  -43.904 1.00 22.79  ? 243  ASN F CB    1 
ATOM   18304 C CG    . ASN F 1 243 ? -59.191  -19.675  -44.038 1.00 24.96  ? 243  ASN F CG    1 
ATOM   18305 O OD1   . ASN F 1 243 ? -59.277  -20.897  -43.843 1.00 23.41  ? 243  ASN F OD1   1 
ATOM   18306 N ND2   . ASN F 1 243 ? -58.051  -19.095  -44.399 1.00 21.85  ? 243  ASN F ND2   1 
ATOM   18307 N N     . GLN F 1 244 ? -62.013  -20.805  -45.255 1.00 20.14  ? 244  GLN F N     1 
ATOM   18308 C CA    . GLN F 1 244 ? -62.709  -21.806  -46.043 1.00 23.64  ? 244  GLN F CA    1 
ATOM   18309 C C     . GLN F 1 244 ? -61.897  -23.109  -46.111 1.00 24.17  ? 244  GLN F C     1 
ATOM   18310 O O     . GLN F 1 244 ? -62.411  -24.105  -46.605 1.00 25.16  ? 244  GLN F O     1 
ATOM   18311 C CB    . GLN F 1 244 ? -62.955  -21.256  -47.458 1.00 22.03  ? 244  GLN F CB    1 
ATOM   18312 C CG    . GLN F 1 244 ? -64.020  -20.172  -47.555 1.00 25.21  ? 244  GLN F CG    1 
ATOM   18313 C CD    . GLN F 1 244 ? -65.381  -20.700  -47.151 1.00 31.68  ? 244  GLN F CD    1 
ATOM   18314 O OE1   . GLN F 1 244 ? -65.933  -21.605  -47.779 1.00 36.68  ? 244  GLN F OE1   1 
ATOM   18315 N NE2   . GLN F 1 244 ? -65.911  -20.218  -46.039 1.00 29.81  ? 244  GLN F NE2   1 
ATOM   18316 N N     . HIS F 1 245 ? -60.640  -23.106  -45.632 1.00 22.43  ? 245  HIS F N     1 
ATOM   18317 C CA    . HIS F 1 245 ? -59.740  -24.240  -45.827 1.00 20.49  ? 245  HIS F CA    1 
ATOM   18318 C C     . HIS F 1 245 ? -59.300  -24.810  -44.487 1.00 21.50  ? 245  HIS F C     1 
ATOM   18319 O O     . HIS F 1 245 ? -59.295  -24.099  -43.470 1.00 22.09  ? 245  HIS F O     1 
ATOM   18320 C CB    . HIS F 1 245 ? -58.542  -23.813  -46.685 1.00 20.82  ? 245  HIS F CB    1 
ATOM   18321 C CG    . HIS F 1 245 ? -58.983  -23.401  -48.059 1.00 26.01  ? 245  HIS F CG    1 
ATOM   18322 N ND1   . HIS F 1 245 ? -59.429  -22.120  -48.321 1.00 25.15  ? 245  HIS F ND1   1 
ATOM   18323 C CD2   . HIS F 1 245 ? -59.109  -24.098  -49.224 1.00 23.12  ? 245  HIS F CD2   1 
ATOM   18324 C CE1   . HIS F 1 245 ? -59.775  -22.034  -49.609 1.00 27.39  ? 245  HIS F CE1   1 
ATOM   18325 N NE2   . HIS F 1 245 ? -59.590  -23.227  -50.176 1.00 25.46  ? 245  HIS F NE2   1 
ATOM   18326 N N     . TRP F 1 246 ? -58.905  -26.090  -44.483 1.00 22.14  ? 246  TRP F N     1 
ATOM   18327 C CA    . TRP F 1 246 ? -58.430  -26.734  -43.266 1.00 21.05  ? 246  TRP F CA    1 
ATOM   18328 C C     . TRP F 1 246 ? -56.913  -26.598  -43.132 1.00 21.18  ? 246  TRP F C     1 
ATOM   18329 O O     . TRP F 1 246 ? -56.422  -26.218  -42.069 1.00 21.36  ? 246  TRP F O     1 
ATOM   18330 C CB    . TRP F 1 246 ? -58.890  -28.188  -43.228 1.00 22.52  ? 246  TRP F CB    1 
ATOM   18331 C CG    . TRP F 1 246 ? -60.393  -28.236  -43.214 1.00 28.48  ? 246  TRP F CG    1 
ATOM   18332 C CD1   . TRP F 1 246 ? -61.215  -28.160  -44.298 1.00 28.44  ? 246  TRP F CD1   1 
ATOM   18333 C CD2   . TRP F 1 246 ? -61.257  -28.313  -42.054 1.00 30.09  ? 246  TRP F CD2   1 
ATOM   18334 N NE1   . TRP F 1 246 ? -62.527  -28.191  -43.904 1.00 28.80  ? 246  TRP F NE1   1 
ATOM   18335 C CE2   . TRP F 1 246 ? -62.593  -28.281  -42.539 1.00 31.52  ? 246  TRP F CE2   1 
ATOM   18336 C CE3   . TRP F 1 246 ? -61.038  -28.419  -40.672 1.00 28.03  ? 246  TRP F CE3   1 
ATOM   18337 C CZ2   . TRP F 1 246 ? -63.707  -28.375  -41.695 1.00 31.56  ? 246  TRP F CZ2   1 
ATOM   18338 C CZ3   . TRP F 1 246 ? -62.139  -28.490  -39.842 1.00 32.58  ? 246  TRP F CZ3   1 
ATOM   18339 C CH2   . TRP F 1 246 ? -63.449  -28.508  -40.350 1.00 31.36  ? 246  TRP F CH2   1 
ATOM   18340 N N     . GLY F 1 247 ? -56.166  -26.952  -44.185 1.00 18.22  ? 247  GLY F N     1 
ATOM   18341 C CA    . GLY F 1 247 ? -54.750  -26.618  -44.218 1.00 19.96  ? 247  GLY F CA    1 
ATOM   18342 C C     . GLY F 1 247 ? -54.595  -25.120  -44.468 1.00 22.04  ? 247  GLY F C     1 
ATOM   18343 O O     . GLY F 1 247 ? -55.550  -24.472  -44.883 1.00 21.16  ? 247  GLY F O     1 
ATOM   18344 N N     . ILE F 1 248 ? -53.408  -24.577  -44.215 1.00 20.34  ? 248  ILE F N     1 
ATOM   18345 C CA    . ILE F 1 248 ? -53.187  -23.156  -44.378 1.00 22.07  ? 248  ILE F CA    1 
ATOM   18346 C C     . ILE F 1 248 ? -53.405  -22.746  -45.840 1.00 24.55  ? 248  ILE F C     1 
ATOM   18347 O O     . ILE F 1 248 ? -53.096  -23.488  -46.769 1.00 24.74  ? 248  ILE F O     1 
ATOM   18348 C CB    . ILE F 1 248 ? -51.790  -22.810  -43.845 1.00 21.46  ? 248  ILE F CB    1 
ATOM   18349 C CG1   . ILE F 1 248 ? -51.602  -21.284  -43.726 1.00 22.95  ? 248  ILE F CG1   1 
ATOM   18350 C CG2   . ILE F 1 248 ? -50.710  -23.503  -44.689 1.00 18.56  ? 248  ILE F CG2   1 
ATOM   18351 C CD1   . ILE F 1 248 ? -50.334  -20.880  -42.974 1.00 23.10  ? 248  ILE F CD1   1 
ATOM   18352 N N     . ALA F 1 249 ? -53.948  -21.539  -46.033 1.00 23.16  ? 249  ALA F N     1 
ATOM   18353 C CA    . ALA F 1 249 ? -54.287  -21.007  -47.338 1.00 22.42  ? 249  ALA F CA    1 
ATOM   18354 C C     . ALA F 1 249 ? -54.118  -19.489  -47.291 1.00 23.53  ? 249  ALA F C     1 
ATOM   18355 O O     . ALA F 1 249 ? -54.995  -18.758  -46.808 1.00 24.16  ? 249  ALA F O     1 
ATOM   18356 C CB    . ALA F 1 249 ? -55.705  -21.391  -47.691 1.00 20.39  ? 249  ALA F CB    1 
ATOM   18357 N N     . ALA F 1 250 ? -52.968  -19.035  -47.795 1.00 23.68  ? 250  ALA F N     1 
ATOM   18358 C CA    . ALA F 1 250 ? -52.465  -17.690  -47.556 1.00 28.28  ? 250  ALA F CA    1 
ATOM   18359 C C     . ALA F 1 250 ? -53.416  -16.656  -48.171 1.00 28.08  ? 250  ALA F C     1 
ATOM   18360 O O     . ALA F 1 250 ? -53.572  -15.576  -47.623 1.00 26.91  ? 250  ALA F O     1 
ATOM   18361 C CB    . ALA F 1 250 ? -51.046  -17.557  -48.087 1.00 23.31  ? 250  ALA F CB    1 
ATOM   18362 N N     . ASN F 1 251 ? -54.004  -16.961  -49.332 1.00 23.75  ? 251  ASN F N     1 
ATOM   18363 C CA    . ASN F 1 251 ? -54.883  -16.012  -49.990 1.00 23.86  ? 251  ASN F CA    1 
ATOM   18364 C C     . ASN F 1 251 ? -56.360  -16.352  -49.812 1.00 22.83  ? 251  ASN F C     1 
ATOM   18365 O O     . ASN F 1 251 ? -57.197  -15.973  -50.632 1.00 22.57  ? 251  ASN F O     1 
ATOM   18366 C CB    . ASN F 1 251 ? -54.504  -15.839  -51.455 1.00 24.43  ? 251  ASN F CB    1 
ATOM   18367 C CG    . ASN F 1 251 ? -53.182  -15.109  -51.575 1.00 30.21  ? 251  ASN F CG    1 
ATOM   18368 O OD1   . ASN F 1 251 ? -52.876  -14.137  -50.842 1.00 34.93  ? 251  ASN F OD1   1 
ATOM   18369 N ND2   . ASN F 1 251 ? -52.371  -15.618  -52.483 1.00 25.44  ? 251  ASN F ND2   1 
ATOM   18370 N N     . ASP F 1 252 ? -56.677  -17.093  -48.749 1.00 20.52  ? 252  ASP F N     1 
ATOM   18371 C CA    . ASP F 1 252 ? -58.057  -17.206  -48.321 1.00 19.86  ? 252  ASP F CA    1 
ATOM   18372 C C     . ASP F 1 252 ? -58.283  -16.128  -47.255 1.00 24.04  ? 252  ASP F C     1 
ATOM   18373 O O     . ASP F 1 252 ? -57.857  -16.298  -46.104 1.00 24.80  ? 252  ASP F O     1 
ATOM   18374 C CB    . ASP F 1 252 ? -58.353  -18.623  -47.847 1.00 21.03  ? 252  ASP F CB    1 
ATOM   18375 C CG    . ASP F 1 252 ? -59.745  -18.813  -47.275 1.00 23.33  ? 252  ASP F CG    1 
ATOM   18376 O OD1   . ASP F 1 252 ? -60.482  -17.799  -47.205 1.00 26.13  ? 252  ASP F OD1   1 
ATOM   18377 O OD2   . ASP F 1 252 ? -60.084  -19.978  -46.906 1.00 24.00  ? 252  ASP F OD2   1 
ATOM   18378 N N     . LEU F 1 253 ? -58.907  -15.015  -47.648 1.00 20.45  ? 253  LEU F N     1 
ATOM   18379 C CA    . LEU F 1 253 ? -59.176  -13.878  -46.771 1.00 22.20  ? 253  LEU F CA    1 
ATOM   18380 C C     . LEU F 1 253 ? -60.570  -14.014  -46.156 1.00 22.68  ? 253  LEU F C     1 
ATOM   18381 O O     . LEU F 1 253 ? -61.010  -13.150  -45.394 1.00 25.02  ? 253  LEU F O     1 
ATOM   18382 C CB    . LEU F 1 253 ? -59.109  -12.585  -47.606 1.00 20.86  ? 253  LEU F CB    1 
ATOM   18383 C CG    . LEU F 1 253 ? -57.884  -12.441  -48.521 1.00 22.66  ? 253  LEU F CG    1 
ATOM   18384 C CD1   . LEU F 1 253 ? -57.805  -11.026  -49.071 1.00 19.84  ? 253  LEU F CD1   1 
ATOM   18385 C CD2   . LEU F 1 253 ? -56.569  -12.791  -47.791 1.00 22.28  ? 253  LEU F CD2   1 
ATOM   18386 N N     . ASN F 1 254 ? -61.300  -15.071  -46.511 1.00 20.90  ? 254  ASN F N     1 
ATOM   18387 C CA    . ASN F 1 254 ? -62.696  -15.174  -46.131 1.00 20.86  ? 254  ASN F CA    1 
ATOM   18388 C C     . ASN F 1 254 ? -62.802  -15.793  -44.724 1.00 23.98  ? 254  ASN F C     1 
ATOM   18389 O O     . ASN F 1 254 ? -63.371  -16.885  -44.544 1.00 21.70  ? 254  ASN F O     1 
ATOM   18390 C CB    . ASN F 1 254 ? -63.461  -15.919  -47.219 1.00 18.03  ? 254  ASN F CB    1 
ATOM   18391 C CG    . ASN F 1 254 ? -64.951  -15.926  -46.957 1.00 22.49  ? 254  ASN F CG    1 
ATOM   18392 O OD1   . ASN F 1 254 ? -65.460  -15.164  -46.113 1.00 25.22  ? 254  ASN F OD1   1 
ATOM   18393 N ND2   . ASN F 1 254 ? -65.681  -16.777  -47.664 1.00 19.26  ? 254  ASN F ND2   1 
ATOM   18394 N N     . TYR F 1 255 ? -62.248  -15.095  -43.712 1.00 23.40  ? 255  TYR F N     1 
ATOM   18395 C CA    . TYR F 1 255 ? -62.301  -15.556  -42.326 1.00 24.88  ? 255  TYR F CA    1 
ATOM   18396 C C     . TYR F 1 255 ? -63.669  -15.254  -41.733 1.00 25.36  ? 255  TYR F C     1 
ATOM   18397 O O     . TYR F 1 255 ? -64.264  -14.227  -42.063 1.00 28.11  ? 255  TYR F O     1 
ATOM   18398 C CB    . TYR F 1 255 ? -61.235  -14.799  -41.536 1.00 23.81  ? 255  TYR F CB    1 
ATOM   18399 C CG    . TYR F 1 255 ? -59.870  -15.449  -41.636 1.00 24.62  ? 255  TYR F CG    1 
ATOM   18400 C CD1   . TYR F 1 255 ? -59.088  -15.268  -42.770 1.00 22.28  ? 255  TYR F CD1   1 
ATOM   18401 C CD2   . TYR F 1 255 ? -59.378  -16.264  -40.608 1.00 23.12  ? 255  TYR F CD2   1 
ATOM   18402 C CE1   . TYR F 1 255 ? -57.834  -15.858  -42.865 1.00 23.05  ? 255  TYR F CE1   1 
ATOM   18403 C CE2   . TYR F 1 255 ? -58.142  -16.883  -40.708 1.00 24.36  ? 255  TYR F CE2   1 
ATOM   18404 C CZ    . TYR F 1 255 ? -57.374  -16.666  -41.840 1.00 24.44  ? 255  TYR F CZ    1 
ATOM   18405 O OH    . TYR F 1 255 ? -56.171  -17.260  -41.982 1.00 22.23  ? 255  TYR F OH    1 
ATOM   18406 N N     . LYS F 1 256 ? -64.163  -16.152  -40.869 1.00 24.75  ? 256  LYS F N     1 
ATOM   18407 C CA    . LYS F 1 256 ? -65.373  -15.892  -40.102 1.00 23.00  ? 256  LYS F CA    1 
ATOM   18408 C C     . LYS F 1 256 ? -65.025  -14.888  -38.994 1.00 23.09  ? 256  LYS F C     1 
ATOM   18409 O O     . LYS F 1 256 ? -63.859  -14.729  -38.630 1.00 21.06  ? 256  LYS F O     1 
ATOM   18410 C CB    . LYS F 1 256 ? -65.782  -17.221  -39.468 1.00 26.61  ? 256  LYS F CB    1 
ATOM   18411 C CG    . LYS F 1 256 ? -66.101  -18.312  -40.481 1.00 31.55  ? 256  LYS F CG    1 
ATOM   18412 C CD    . LYS F 1 256 ? -66.323  -19.683  -39.858 1.00 31.75  ? 256  LYS F CD    1 
ATOM   18413 C CE    . LYS F 1 256 ? -66.498  -20.732  -40.957 1.00 36.24  ? 256  LYS F CE    1 
ATOM   18414 N NZ    . LYS F 1 256 ? -65.387  -20.780  -41.922 1.00 24.72  ? 256  LYS F NZ    1 
ATOM   18415 N N     . SER F 1 257 ? -66.028  -14.199  -38.448 1.00 23.28  ? 257  SER F N     1 
ATOM   18416 C CA    . SER F 1 257 ? -65.754  -13.306  -37.336 1.00 22.32  ? 257  SER F CA    1 
ATOM   18417 C C     . SER F 1 257 ? -65.434  -14.112  -36.080 1.00 20.99  ? 257  SER F C     1 
ATOM   18418 O O     . SER F 1 257 ? -65.979  -15.189  -35.861 1.00 17.65  ? 257  SER F O     1 
ATOM   18419 C CB    . SER F 1 257 ? -66.913  -12.365  -37.074 1.00 19.94  ? 257  SER F CB    1 
ATOM   18420 O OG    . SER F 1 257 ? -67.997  -13.126  -36.581 1.00 25.37  ? 257  SER F OG    1 
ATOM   18421 N N     . PRO F 1 258 ? -64.566  -13.576  -35.190 1.00 21.31  ? 258  PRO F N     1 
ATOM   18422 C CA    . PRO F 1 258 ? -64.440  -14.099  -33.827 1.00 19.59  ? 258  PRO F CA    1 
ATOM   18423 C C     . PRO F 1 258 ? -65.792  -14.305  -33.135 1.00 19.09  ? 258  PRO F C     1 
ATOM   18424 O O     . PRO F 1 258 ? -65.983  -15.298  -32.434 1.00 22.36  ? 258  PRO F O     1 
ATOM   18425 C CB    . PRO F 1 258 ? -63.464  -13.126  -33.185 1.00 19.60  ? 258  PRO F CB    1 
ATOM   18426 C CG    . PRO F 1 258 ? -62.672  -12.603  -34.369 1.00 18.71  ? 258  PRO F CG    1 
ATOM   18427 C CD    . PRO F 1 258 ? -63.655  -12.452  -35.462 1.00 19.54  ? 258  PRO F CD    1 
ATOM   18428 N N     . ALA F 1 259 ? -66.756  -13.428  -33.412 1.00 18.08  ? 259  ALA F N     1 
ATOM   18429 C CA    . ALA F 1 259 ? -68.066  -13.540  -32.789 1.00 21.67  ? 259  ALA F CA    1 
ATOM   18430 C C     . ALA F 1 259 ? -68.768  -14.825  -33.245 1.00 23.10  ? 259  ALA F C     1 
ATOM   18431 O O     . ALA F 1 259 ? -69.381  -15.530  -32.438 1.00 23.36  ? 259  ALA F O     1 
ATOM   18432 C CB    . ALA F 1 259 ? -68.929  -12.308  -33.094 1.00 20.36  ? 259  ALA F CB    1 
ATOM   18433 N N     . GLU F 1 260 ? -68.697  -15.114  -34.547 1.00 23.40  ? 260  GLU F N     1 
ATOM   18434 C CA    . GLU F 1 260 ? -69.323  -16.312  -35.079 1.00 26.55  ? 260  GLU F CA    1 
ATOM   18435 C C     . GLU F 1 260 ? -68.656  -17.548  -34.450 1.00 25.85  ? 260  GLU F C     1 
ATOM   18436 O O     . GLU F 1 260 ? -69.317  -18.539  -34.130 1.00 24.48  ? 260  GLU F O     1 
ATOM   18437 C CB    . GLU F 1 260 ? -69.297  -16.322  -36.609 1.00 27.34  ? 260  GLU F CB    1 
ATOM   18438 C CG    . GLU F 1 260 ? -69.764  -17.655  -37.181 1.00 32.09  ? 260  GLU F CG    1 
ATOM   18439 C CD    . GLU F 1 260 ? -69.897  -17.855  -38.684 1.00 38.55  ? 260  GLU F CD    1 
ATOM   18440 O OE1   . GLU F 1 260 ? -69.681  -16.892  -39.430 1.00 41.12  ? 260  GLU F OE1   1 
ATOM   18441 O OE2   . GLU F 1 260 ? -70.191  -18.994  -39.123 1.00 42.54  ? 260  GLU F OE2   1 
ATOM   18442 N N     . MET F 1 261 ? -67.336  -17.476  -34.258 1.00 23.41  ? 261  MET F N     1 
ATOM   18443 C CA    . MET F 1 261 ? -66.615  -18.569  -33.633 1.00 24.28  ? 261  MET F CA    1 
ATOM   18444 C C     . MET F 1 261 ? -67.154  -18.820  -32.217 1.00 26.18  ? 261  MET F C     1 
ATOM   18445 O O     . MET F 1 261 ? -67.482  -19.964  -31.876 1.00 24.43  ? 261  MET F O     1 
ATOM   18446 C CB    . MET F 1 261 ? -65.113  -18.280  -33.665 1.00 22.36  ? 261  MET F CB    1 
ATOM   18447 C CG    . MET F 1 261 ? -64.294  -19.279  -32.884 1.00 25.53  ? 261  MET F CG    1 
ATOM   18448 S SD    . MET F 1 261 ? -62.568  -18.768  -32.673 1.00 31.70  ? 261  MET F SD    1 
ATOM   18449 C CE    . MET F 1 261 ? -62.709  -17.206  -31.783 1.00 26.56  ? 261  MET F CE    1 
ATOM   18450 N N     . ILE F 1 262 ? -67.302  -17.744  -31.417 1.00 22.86  ? 262  ILE F N     1 
ATOM   18451 C CA    . ILE F 1 262 ? -67.847  -17.890  -30.081 1.00 22.75  ? 262  ILE F CA    1 
ATOM   18452 C C     . ILE F 1 262 ? -69.265  -18.458  -30.120 1.00 22.70  ? 262  ILE F C     1 
ATOM   18453 O O     . ILE F 1 262 ? -69.593  -19.369  -29.363 1.00 25.68  ? 262  ILE F O     1 
ATOM   18454 C CB    . ILE F 1 262 ? -67.741  -16.581  -29.282 1.00 21.12  ? 262  ILE F CB    1 
ATOM   18455 C CG1   . ILE F 1 262 ? -66.282  -16.318  -28.946 1.00 19.75  ? 262  ILE F CG1   1 
ATOM   18456 C CG2   . ILE F 1 262 ? -68.580  -16.658  -28.005 1.00 16.86  ? 262  ILE F CG2   1 
ATOM   18457 C CD1   . ILE F 1 262 ? -65.991  -14.880  -28.574 1.00 23.79  ? 262  ILE F CD1   1 
ATOM   18458 N N     . GLU F 1 263 ? -70.111  -17.937  -31.010 1.00 22.62  ? 263  GLU F N     1 
ATOM   18459 C CA    . GLU F 1 263 ? -71.476  -18.440  -31.107 1.00 22.69  ? 263  GLU F CA    1 
ATOM   18460 C C     . GLU F 1 263 ? -71.505  -19.926  -31.476 1.00 24.94  ? 263  GLU F C     1 
ATOM   18461 O O     . GLU F 1 263 ? -72.404  -20.640  -31.014 1.00 23.92  ? 263  GLU F O     1 
ATOM   18462 C CB    . GLU F 1 263 ? -72.332  -17.633  -32.072 1.00 22.55  ? 263  GLU F CB    1 
ATOM   18463 C CG    . GLU F 1 263 ? -72.604  -16.213  -31.592 1.00 26.56  ? 263  GLU F CG    1 
ATOM   18464 C CD    . GLU F 1 263 ? -73.629  -15.422  -32.404 1.00 36.46  ? 263  GLU F CD    1 
ATOM   18465 O OE1   . GLU F 1 263 ? -74.186  -16.011  -33.370 1.00 38.76  ? 263  GLU F OE1   1 
ATOM   18466 O OE2   . GLU F 1 263 ? -73.911  -14.231  -32.065 1.00 35.90  ? 263  GLU F OE2   1 
ATOM   18467 N N     . THR F 1 264 ? -70.533  -20.394  -32.287 1.00 23.52  ? 264  THR F N     1 
ATOM   18468 C CA    . THR F 1 264 ? -70.548  -21.780  -32.743 1.00 21.66  ? 264  THR F CA    1 
ATOM   18469 C C     . THR F 1 264 ? -70.140  -22.680  -31.580 1.00 22.99  ? 264  THR F C     1 
ATOM   18470 O O     . THR F 1 264 ? -70.721  -23.757  -31.401 1.00 23.28  ? 264  THR F O     1 
ATOM   18471 C CB    . THR F 1 264 ? -69.632  -21.983  -33.952 1.00 22.11  ? 264  THR F CB    1 
ATOM   18472 O OG1   . THR F 1 264 ? -70.087  -21.038  -34.913 1.00 23.93  ? 264  THR F OG1   1 
ATOM   18473 C CG2   . THR F 1 264 ? -69.749  -23.363  -34.573 1.00 21.69  ? 264  THR F CG2   1 
ATOM   18474 N N     . VAL F 1 265 ? -69.158  -22.231  -30.778 1.00 19.65  ? 265  VAL F N     1 
ATOM   18475 C CA    . VAL F 1 265 ? -68.768  -22.999  -29.607 1.00 20.86  ? 265  VAL F CA    1 
ATOM   18476 C C     . VAL F 1 265 ? -69.970  -23.141  -28.674 1.00 24.45  ? 265  VAL F C     1 
ATOM   18477 O O     . VAL F 1 265 ? -70.300  -24.254  -28.254 1.00 26.72  ? 265  VAL F O     1 
ATOM   18478 C CB    . VAL F 1 265 ? -67.567  -22.351  -28.899 1.00 21.32  ? 265  VAL F CB    1 
ATOM   18479 C CG1   . VAL F 1 265 ? -67.303  -23.002  -27.546 1.00 22.41  ? 265  VAL F CG1   1 
ATOM   18480 C CG2   . VAL F 1 265 ? -66.321  -22.398  -29.778 1.00 19.34  ? 265  VAL F CG2   1 
ATOM   18481 N N     . ALA F 1 266 ? -70.664  -22.028  -28.388 1.00 22.27  ? 266  ALA F N     1 
ATOM   18482 C CA    . ALA F 1 266 ? -71.813  -22.107  -27.492 1.00 21.01  ? 266  ALA F CA    1 
ATOM   18483 C C     . ALA F 1 266 ? -72.875  -23.032  -28.088 1.00 22.18  ? 266  ALA F C     1 
ATOM   18484 O O     . ALA F 1 266 ? -73.517  -23.818  -27.378 1.00 22.36  ? 266  ALA F O     1 
ATOM   18485 C CB    . ALA F 1 266 ? -72.377  -20.725  -27.236 1.00 17.40  ? 266  ALA F CB    1 
ATOM   18486 N N     . HIS F 1 267 ? -73.074  -22.920  -29.406 1.00 20.93  ? 267  HIS F N     1 
ATOM   18487 C CA    . HIS F 1 267 ? -74.119  -23.665  -30.104 1.00 22.49  ? 267  HIS F CA    1 
ATOM   18488 C C     . HIS F 1 267 ? -73.861  -25.179  -30.001 1.00 23.44  ? 267  HIS F C     1 
ATOM   18489 O O     . HIS F 1 267 ? -74.813  -25.940  -29.815 1.00 22.85  ? 267  HIS F O     1 
ATOM   18490 C CB    . HIS F 1 267 ? -74.200  -23.220  -31.566 1.00 21.58  ? 267  HIS F CB    1 
ATOM   18491 C CG    . HIS F 1 267 ? -75.149  -24.060  -32.374 1.00 25.63  ? 267  HIS F CG    1 
ATOM   18492 N ND1   . HIS F 1 267 ? -76.533  -24.001  -32.232 1.00 23.28  ? 267  HIS F ND1   1 
ATOM   18493 C CD2   . HIS F 1 267 ? -74.885  -25.029  -33.319 1.00 24.74  ? 267  HIS F CD2   1 
ATOM   18494 C CE1   . HIS F 1 267 ? -77.087  -24.841  -33.088 1.00 22.96  ? 267  HIS F CE1   1 
ATOM   18495 N NE2   . HIS F 1 267 ? -76.102  -25.474  -33.767 1.00 26.95  ? 267  HIS F NE2   1 
ATOM   18496 N N     . ALA F 1 268 ? -72.612  -25.589  -30.048 1.00 20.74  ? 268  ALA F N     1 
ATOM   18497 C CA    . ALA F 1 268 ? -72.283  -26.977  -29.947 1.00 23.61  ? 268  ALA F CA    1 
ATOM   18498 C C     . ALA F 1 268 ? -72.725  -27.567  -28.630 1.00 22.51  ? 268  ALA F C     1 
ATOM   18499 O O     . ALA F 1 268 ? -73.256  -28.623  -28.603 1.00 23.78  ? 268  ALA F O     1 
ATOM   18500 C CB    . ALA F 1 268 ? -70.803  -27.174  -30.137 1.00 22.92  ? 268  ALA F CB    1 
ATOM   18501 N N     . ARG F 1 269 ? -72.490  -26.846  -27.558 1.00 20.59  ? 269  ARG F N     1 
ATOM   18502 C CA    . ARG F 1 269 ? -72.875  -27.233  -26.232 1.00 21.87  ? 269  ARG F CA    1 
ATOM   18503 C C     . ARG F 1 269 ? -74.362  -27.319  -26.086 1.00 23.94  ? 269  ARG F C     1 
ATOM   18504 O O     . ARG F 1 269 ? -74.859  -28.216  -25.503 1.00 24.06  ? 269  ARG F O     1 
ATOM   18505 C CB    . ARG F 1 269 ? -72.270  -26.313  -25.195 1.00 20.50  ? 269  ARG F CB    1 
ATOM   18506 C CG    . ARG F 1 269 ? -70.776  -26.253  -25.274 1.00 22.36  ? 269  ARG F CG    1 
ATOM   18507 C CD    . ARG F 1 269 ? -70.153  -27.610  -25.480 1.00 22.81  ? 269  ARG F CD    1 
ATOM   18508 N NE    . ARG F 1 269 ? -69.921  -28.302  -24.247 1.00 23.00  ? 269  ARG F NE    1 
ATOM   18509 C CZ    . ARG F 1 269 ? -69.771  -29.593  -24.138 1.00 25.50  ? 269  ARG F CZ    1 
ATOM   18510 N NH1   . ARG F 1 269 ? -69.830  -30.344  -25.173 1.00 25.15  ? 269  ARG F NH1   1 
ATOM   18511 N NH2   . ARG F 1 269 ? -69.533  -30.124  -22.989 1.00 24.46  ? 269  ARG F NH2   1 
ATOM   18512 N N     . HIS F 1 270 ? -75.053  -26.383  -26.687 1.00 25.36  ? 270  HIS F N     1 
ATOM   18513 C CA    . HIS F 1 270 ? -76.478  -26.330  -26.670 1.00 25.06  ? 270  HIS F CA    1 
ATOM   18514 C C     . HIS F 1 270 ? -77.115  -27.544  -27.333 1.00 26.06  ? 270  HIS F C     1 
ATOM   18515 O O     . HIS F 1 270 ? -78.110  -28.009  -26.894 1.00 25.37  ? 270  HIS F O     1 
ATOM   18516 C CB    . HIS F 1 270 ? -76.950  -25.032  -27.301 1.00 26.41  ? 270  HIS F CB    1 
ATOM   18517 C CG    . HIS F 1 270 ? -78.426  -24.922  -27.406 1.00 32.34  ? 270  HIS F CG    1 
ATOM   18518 N ND1   . HIS F 1 270 ? -79.049  -24.492  -28.539 1.00 35.02  ? 270  HIS F ND1   1 
ATOM   18519 C CD2   . HIS F 1 270 ? -79.407  -25.230  -26.538 1.00 28.04  ? 270  HIS F CD2   1 
ATOM   18520 C CE1   . HIS F 1 270 ? -80.345  -24.506  -28.359 1.00 33.09  ? 270  HIS F CE1   1 
ATOM   18521 N NE2   . HIS F 1 270 ? -80.588  -24.953  -27.155 1.00 31.73  ? 270  HIS F NE2   1 
ATOM   18522 N N     . ILE F 1 271 ? -76.541  -28.022  -28.411 1.00 24.51  ? 271  ILE F N     1 
ATOM   18523 C CA    . ILE F 1 271 ? -77.049  -29.193  -29.083 1.00 24.32  ? 271  ILE F CA    1 
ATOM   18524 C C     . ILE F 1 271 ? -76.523  -30.520  -28.536 1.00 25.72  ? 271  ILE F C     1 
ATOM   18525 O O     . ILE F 1 271 ? -76.912  -31.543  -28.991 1.00 27.90  ? 271  ILE F O     1 
ATOM   18526 C CB    . ILE F 1 271 ? -76.926  -29.145  -30.617 1.00 24.65  ? 271  ILE F CB    1 
ATOM   18527 C CG1   . ILE F 1 271 ? -75.482  -29.220  -31.073 1.00 25.01  ? 271  ILE F CG1   1 
ATOM   18528 C CG2   . ILE F 1 271 ? -77.651  -27.959  -31.196 1.00 21.88  ? 271  ILE F CG2   1 
ATOM   18529 C CD1   . ILE F 1 271 ? -75.302  -29.466  -32.527 1.00 23.08  ? 271  ILE F CD1   1 
ATOM   18530 N N     . GLY F 1 272 ? -75.620  -30.474  -27.581 1.00 21.79  ? 272  GLY F N     1 
ATOM   18531 C CA    . GLY F 1 272 ? -75.098  -31.684  -26.965 1.00 21.27  ? 272  GLY F CA    1 
ATOM   18532 C C     . GLY F 1 272 ? -73.925  -32.307  -27.734 1.00 24.55  ? 272  GLY F C     1 
ATOM   18533 O O     . GLY F 1 272 ? -73.828  -33.526  -27.796 1.00 25.71  ? 272  GLY F O     1 
ATOM   18534 N N     . ALA F 1 273 ? -73.017  -31.476  -28.284 1.00 24.56  ? 273  ALA F N     1 
ATOM   18535 C CA    . ALA F 1 273 ? -71.873  -31.952  -29.045 1.00 21.18  ? 273  ALA F CA    1 
ATOM   18536 C C     . ALA F 1 273 ? -70.600  -31.299  -28.510 1.00 21.30  ? 273  ALA F C     1 
ATOM   18537 O O     . ALA F 1 273 ? -70.660  -30.252  -27.860 1.00 22.69  ? 273  ALA F O     1 
ATOM   18538 C CB    . ALA F 1 273 ? -72.065  -31.637  -30.509 1.00 20.17  ? 273  ALA F CB    1 
ATOM   18539 N N     . ASN F 1 274 ? -69.458  -31.934  -28.780 1.00 21.85  ? 274  ASN F N     1 
ATOM   18540 C CA    . ASN F 1 274 ? -68.186  -31.238  -28.650 1.00 22.77  ? 274  ASN F CA    1 
ATOM   18541 C C     . ASN F 1 274 ? -67.967  -30.364  -29.894 1.00 22.96  ? 274  ASN F C     1 
ATOM   18542 O O     . ASN F 1 274 ? -68.665  -30.512  -30.911 1.00 22.63  ? 274  ASN F O     1 
ATOM   18543 C CB    . ASN F 1 274 ? -67.039  -32.228  -28.513 1.00 20.97  ? 274  ASN F CB    1 
ATOM   18544 C CG    . ASN F 1 274 ? -66.925  -32.817  -27.118 1.00 24.26  ? 274  ASN F CG    1 
ATOM   18545 O OD1   . ASN F 1 274 ? -67.882  -32.769  -26.323 1.00 25.01  ? 274  ASN F OD1   1 
ATOM   18546 N ND2   . ASN F 1 274 ? -65.769  -33.408  -26.825 1.00 23.77  ? 274  ASN F ND2   1 
ATOM   18547 N N     . ILE F 1 275 ? -66.999  -29.488  -29.808 1.00 21.20  ? 275  ILE F N     1 
ATOM   18548 C CA    . ILE F 1 275 ? -66.613  -28.659  -30.901 1.00 22.04  ? 275  ILE F CA    1 
ATOM   18549 C C     . ILE F 1 275 ? -65.106  -28.676  -31.140 1.00 21.20  ? 275  ILE F C     1 
ATOM   18550 O O     . ILE F 1 275 ? -64.383  -28.620  -30.222 1.00 24.60  ? 275  ILE F O     1 
ATOM   18551 C CB    . ILE F 1 275 ? -67.149  -27.223  -30.727 1.00 21.56  ? 275  ILE F CB    1 
ATOM   18552 C CG1   . ILE F 1 275 ? -66.597  -26.274  -31.767 1.00 26.38  ? 275  ILE F CG1   1 
ATOM   18553 C CG2   . ILE F 1 275 ? -66.786  -26.657  -29.395 1.00 21.36  ? 275  ILE F CG2   1 
ATOM   18554 C CD1   . ILE F 1 275 ? -67.300  -26.276  -33.069 1.00 27.94  ? 275  ILE F CD1   1 
ATOM   18555 N N     . LEU F 1 276 ? -64.663  -28.875  -32.371 1.00 22.30  ? 276  LEU F N     1 
ATOM   18556 C CA    . LEU F 1 276 ? -63.254  -28.705  -32.746 1.00 24.28  ? 276  LEU F CA    1 
ATOM   18557 C C     . LEU F 1 276 ? -63.090  -27.378  -33.473 1.00 22.50  ? 276  LEU F C     1 
ATOM   18558 O O     . LEU F 1 276 ? -63.839  -27.110  -34.418 1.00 23.82  ? 276  LEU F O     1 
ATOM   18559 C CB    . LEU F 1 276 ? -62.807  -29.830  -33.680 1.00 24.79  ? 276  LEU F CB    1 
ATOM   18560 C CG    . LEU F 1 276 ? -62.729  -31.245  -33.100 1.00 28.33  ? 276  LEU F CG    1 
ATOM   18561 C CD1   . LEU F 1 276 ? -62.183  -32.199  -34.183 1.00 24.28  ? 276  LEU F CD1   1 
ATOM   18562 C CD2   . LEU F 1 276 ? -61.784  -31.196  -31.884 1.00 28.71  ? 276  LEU F CD2   1 
ATOM   18563 N N     . VAL F 1 277 ? -62.109  -26.571  -33.045 1.00 21.02  ? 277  VAL F N     1 
ATOM   18564 C CA    . VAL F 1 277 ? -61.739  -25.376  -33.777 1.00 20.67  ? 277  VAL F CA    1 
ATOM   18565 C C     . VAL F 1 277 ? -60.416  -25.671  -34.474 1.00 23.25  ? 277  VAL F C     1 
ATOM   18566 O O     . VAL F 1 277 ? -59.441  -26.051  -33.821 1.00 23.43  ? 277  VAL F O     1 
ATOM   18567 C CB    . VAL F 1 277 ? -61.617  -24.177  -32.813 1.00 21.76  ? 277  VAL F CB    1 
ATOM   18568 C CG1   . VAL F 1 277 ? -61.120  -22.905  -33.525 1.00 21.44  ? 277  VAL F CG1   1 
ATOM   18569 C CG2   . VAL F 1 277 ? -62.936  -23.887  -32.110 1.00 20.65  ? 277  VAL F CG2   1 
ATOM   18570 N N     . ASN F 1 278 ? -60.387  -25.489  -35.793 1.00 22.24  ? 278  ASN F N     1 
ATOM   18571 C CA    . ASN F 1 278 ? -59.271  -25.932  -36.602 1.00 21.82  ? 278  ASN F CA    1 
ATOM   18572 C C     . ASN F 1 278 ? -58.265  -24.811  -36.845 1.00 23.15  ? 278  ASN F C     1 
ATOM   18573 O O     . ASN F 1 278 ? -58.653  -23.688  -37.155 1.00 22.49  ? 278  ASN F O     1 
ATOM   18574 C CB    . ASN F 1 278 ? -59.740  -26.397  -37.975 1.00 22.01  ? 278  ASN F CB    1 
ATOM   18575 C CG    . ASN F 1 278 ? -58.541  -26.811  -38.799 1.00 24.81  ? 278  ASN F CG    1 
ATOM   18576 O OD1   . ASN F 1 278 ? -57.873  -27.793  -38.435 1.00 23.88  ? 278  ASN F OD1   1 
ATOM   18577 N ND2   . ASN F 1 278 ? -58.220  -26.052  -39.849 1.00 20.32  ? 278  ASN F ND2   1 
ATOM   18578 N N     . ILE F 1 279 ? -56.971  -25.144  -36.768 1.00 21.84  ? 279  ILE F N     1 
ATOM   18579 C CA    . ILE F 1 279 ? -55.928  -24.262  -37.277 1.00 24.33  ? 279  ILE F CA    1 
ATOM   18580 C C     . ILE F 1 279 ? -55.032  -25.061  -38.241 1.00 23.35  ? 279  ILE F C     1 
ATOM   18581 O O     . ILE F 1 279 ? -54.767  -26.252  -38.046 1.00 23.91  ? 279  ILE F O     1 
ATOM   18582 C CB    . ILE F 1 279 ? -55.112  -23.634  -36.130 1.00 26.69  ? 279  ILE F CB    1 
ATOM   18583 C CG1   . ILE F 1 279 ? -54.306  -24.680  -35.426 1.00 28.50  ? 279  ILE F CG1   1 
ATOM   18584 C CG2   . ILE F 1 279 ? -55.991  -22.886  -35.123 1.00 25.57  ? 279  ILE F CG2   1 
ATOM   18585 C CD1   . ILE F 1 279 ? -53.387  -24.121  -34.360 1.00 32.84  ? 279  ILE F CD1   1 
ATOM   18586 N N     . GLY F 1 280 ? -54.543  -24.416  -39.297 1.00 20.27  ? 280  GLY F N     1 
ATOM   18587 C CA    . GLY F 1 280 ? -53.568  -25.009  -40.198 1.00 20.92  ? 280  GLY F CA    1 
ATOM   18588 C C     . GLY F 1 280 ? -52.173  -24.460  -39.909 1.00 22.34  ? 280  GLY F C     1 
ATOM   18589 O O     . GLY F 1 280 ? -52.015  -23.256  -39.978 1.00 24.08  ? 280  GLY F O     1 
ATOM   18590 N N     . LEU F 1 281 ? -51.178  -25.320  -39.616 1.00 24.10  ? 281  LEU F N     1 
ATOM   18591 C CA    . LEU F 1 281 ? -49.820  -24.833  -39.373 1.00 23.19  ? 281  LEU F CA    1 
ATOM   18592 C C     . LEU F 1 281 ? -49.157  -24.383  -40.672 1.00 22.38  ? 281  LEU F C     1 
ATOM   18593 O O     . LEU F 1 281 ? -49.585  -24.798  -41.771 1.00 23.08  ? 281  LEU F O     1 
ATOM   18594 C CB    . LEU F 1 281 ? -48.984  -25.897  -38.664 1.00 22.71  ? 281  LEU F CB    1 
ATOM   18595 C CG    . LEU F 1 281 ? -49.572  -26.481  -37.370 1.00 23.11  ? 281  LEU F CG    1 
ATOM   18596 C CD1   . LEU F 1 281 ? -48.643  -27.475  -36.693 1.00 20.04  ? 281  LEU F CD1   1 
ATOM   18597 C CD2   . LEU F 1 281 ? -49.999  -25.399  -36.371 1.00 20.20  ? 281  LEU F CD2   1 
ATOM   18598 N N     . THR F 1 282 ? -48.125  -23.519  -40.547 1.00 19.83  ? 282  THR F N     1 
ATOM   18599 C CA    . THR F 1 282 ? -47.265  -23.162  -41.681 1.00 21.07  ? 282  THR F CA    1 
ATOM   18600 C C     . THR F 1 282 ? -46.476  -24.403  -42.131 1.00 23.86  ? 282  THR F C     1 
ATOM   18601 O O     . THR F 1 282 ? -46.414  -25.428  -41.415 1.00 23.54  ? 282  THR F O     1 
ATOM   18602 C CB    . THR F 1 282 ? -46.279  -22.045  -41.299 1.00 22.87  ? 282  THR F CB    1 
ATOM   18603 O OG1   . THR F 1 282 ? -45.320  -22.613  -40.375 1.00 25.41  ? 282  THR F OG1   1 
ATOM   18604 C CG2   . THR F 1 282 ? -46.999  -20.824  -40.739 1.00 19.12  ? 282  THR F CG2   1 
ATOM   18605 N N     . GLY F 1 283 ? -45.838  -24.288  -43.312 1.00 23.62  ? 283  GLY F N     1 
ATOM   18606 C CA    . GLY F 1 283 ? -45.023  -25.374  -43.850 1.00 22.51  ? 283  GLY F CA    1 
ATOM   18607 C C     . GLY F 1 283 ? -44.096  -25.975  -42.780 1.00 27.10  ? 283  GLY F C     1 
ATOM   18608 O O     . GLY F 1 283 ? -44.024  -27.207  -42.639 1.00 24.93  ? 283  GLY F O     1 
ATOM   18609 N N     . THR F 1 284 ? -43.431  -25.103  -41.990 1.00 23.91  ? 284  THR F N     1 
ATOM   18610 C CA    . THR F 1 284 ? -42.430  -25.569  -41.036 1.00 25.89  ? 284  THR F CA    1 
ATOM   18611 C C     . THR F 1 284 ? -43.045  -25.873  -39.659 1.00 30.41  ? 284  THR F C     1 
ATOM   18612 O O     . THR F 1 284 ? -42.312  -26.185  -38.704 1.00 30.34  ? 284  THR F O     1 
ATOM   18613 C CB    . THR F 1 284 ? -41.300  -24.548  -40.917 1.00 30.16  ? 284  THR F CB    1 
ATOM   18614 O OG1   . THR F 1 284 ? -41.975  -23.352  -40.516 1.00 30.25  ? 284  THR F OG1   1 
ATOM   18615 C CG2   . THR F 1 284 ? -40.513  -24.370  -42.213 1.00 24.70  ? 284  THR F CG2   1 
ATOM   18616 N N     . GLY F 1 285 ? -44.385  -25.790  -39.524 1.00 28.70  ? 285  GLY F N     1 
ATOM   18617 C CA    . GLY F 1 285 ? -45.004  -26.255  -38.288 1.00 22.85  ? 285  GLY F CA    1 
ATOM   18618 C C     . GLY F 1 285 ? -45.312  -25.165  -37.242 1.00 23.81  ? 285  GLY F C     1 
ATOM   18619 O O     . GLY F 1 285 ? -45.622  -25.499  -36.095 1.00 24.30  ? 285  GLY F O     1 
ATOM   18620 N N     . ALA F 1 286 ? -45.286  -23.882  -37.615 1.00 21.94  ? 286  ALA F N     1 
ATOM   18621 C CA    . ALA F 1 286 ? -45.662  -22.823  -36.668 1.00 24.50  ? 286  ALA F CA    1 
ATOM   18622 C C     . ALA F 1 286 ? -47.174  -22.577  -36.711 1.00 25.61  ? 286  ALA F C     1 
ATOM   18623 O O     . ALA F 1 286 ? -47.829  -22.807  -37.733 1.00 28.09  ? 286  ALA F O     1 
ATOM   18624 C CB    . ALA F 1 286 ? -44.926  -21.517  -36.976 1.00 20.61  ? 286  ALA F CB    1 
ATOM   18625 N N     . ILE F 1 287 ? -47.725  -22.101  -35.593 1.00 25.67  ? 287  ILE F N     1 
ATOM   18626 C CA    . ILE F 1 287 ? -49.073  -21.561  -35.574 1.00 24.61  ? 287  ILE F CA    1 
ATOM   18627 C C     . ILE F 1 287 ? -49.044  -20.206  -36.259 1.00 25.76  ? 287  ILE F C     1 
ATOM   18628 O O     . ILE F 1 287 ? -48.327  -19.312  -35.852 1.00 29.26  ? 287  ILE F O     1 
ATOM   18629 C CB    . ILE F 1 287 ? -49.599  -21.422  -34.143 1.00 24.96  ? 287  ILE F CB    1 
ATOM   18630 C CG1   . ILE F 1 287 ? -49.539  -22.763  -33.418 1.00 25.61  ? 287  ILE F CG1   1 
ATOM   18631 C CG2   . ILE F 1 287 ? -51.040  -20.902  -34.186 1.00 19.88  ? 287  ILE F CG2   1 
ATOM   18632 C CD1   . ILE F 1 287 ? -50.096  -22.685  -32.006 1.00 27.35  ? 287  ILE F CD1   1 
ATOM   18633 N N     . PRO F 1 288 ? -49.799  -19.995  -37.356 1.00 25.15  ? 288  PRO F N     1 
ATOM   18634 C CA    . PRO F 1 288 ? -49.753  -18.695  -38.024 1.00 26.06  ? 288  PRO F CA    1 
ATOM   18635 C C     . PRO F 1 288 ? -50.366  -17.591  -37.158 1.00 28.14  ? 288  PRO F C     1 
ATOM   18636 O O     . PRO F 1 288 ? -51.247  -17.880  -36.328 1.00 24.44  ? 288  PRO F O     1 
ATOM   18637 C CB    . PRO F 1 288 ? -50.513  -18.916  -39.329 1.00 21.04  ? 288  PRO F CB    1 
ATOM   18638 C CG    . PRO F 1 288 ? -51.289  -20.229  -39.104 1.00 21.56  ? 288  PRO F CG    1 
ATOM   18639 C CD    . PRO F 1 288 ? -50.721  -20.967  -37.963 1.00 20.79  ? 288  PRO F CD    1 
ATOM   18640 N N     . ALA F 1 289 ? -49.940  -16.347  -37.410 1.00 27.62  ? 289  ALA F N     1 
ATOM   18641 C CA    . ALA F 1 289 ? -50.374  -15.208  -36.602 1.00 29.55  ? 289  ALA F CA    1 
ATOM   18642 C C     . ALA F 1 289 ? -51.907  -15.100  -36.569 1.00 28.52  ? 289  ALA F C     1 
ATOM   18643 O O     . ALA F 1 289 ? -52.478  -14.847  -35.507 1.00 25.80  ? 289  ALA F O     1 
ATOM   18644 C CB    . ALA F 1 289 ? -49.706  -13.904  -37.071 1.00 25.35  ? 289  ALA F CB    1 
ATOM   18645 N N     . ALA F 1 290 ? -52.582  -15.316  -37.715 1.00 26.62  ? 290  ALA F N     1 
ATOM   18646 C CA    . ALA F 1 290 ? -54.031  -15.149  -37.734 1.00 26.65  ? 290  ALA F CA    1 
ATOM   18647 C C     . ALA F 1 290 ? -54.693  -16.131  -36.770 1.00 27.71  ? 290  ALA F C     1 
ATOM   18648 O O     . ALA F 1 290 ? -55.615  -15.779  -36.044 1.00 28.43  ? 290  ALA F O     1 
ATOM   18649 C CB    . ALA F 1 290 ? -54.607  -15.252  -39.138 1.00 26.09  ? 290  ALA F CB    1 
ATOM   18650 N N     . ALA F 1 291 ? -54.215  -17.372  -36.754 1.00 26.73  ? 291  ALA F N     1 
ATOM   18651 C CA    . ALA F 1 291 ? -54.808  -18.370  -35.884 1.00 26.73  ? 291  ALA F CA    1 
ATOM   18652 C C     . ALA F 1 291 ? -54.588  -18.000  -34.412 1.00 24.09  ? 291  ALA F C     1 
ATOM   18653 O O     . ALA F 1 291 ? -55.484  -18.208  -33.600 1.00 22.57  ? 291  ALA F O     1 
ATOM   18654 C CB    . ALA F 1 291 ? -54.256  -19.725  -36.214 1.00 22.99  ? 291  ALA F CB    1 
ATOM   18655 N N     . GLN F 1 292 ? -53.412  -17.450  -34.093 1.00 22.80  ? 292  GLN F N     1 
ATOM   18656 C CA    . GLN F 1 292 ? -53.126  -16.979  -32.741 1.00 29.51  ? 292  GLN F CA    1 
ATOM   18657 C C     . GLN F 1 292 ? -54.139  -15.926  -32.297 1.00 25.38  ? 292  GLN F C     1 
ATOM   18658 O O     . GLN F 1 292 ? -54.613  -15.998  -31.169 1.00 25.45  ? 292  GLN F O     1 
ATOM   18659 C CB    . GLN F 1 292 ? -51.688  -16.503  -32.531 1.00 36.09  ? 292  GLN F CB    1 
ATOM   18660 C CG    . GLN F 1 292 ? -50.705  -17.638  -32.258 1.00 47.48  ? 292  GLN F CG    1 
ATOM   18661 C CD    . GLN F 1 292 ? -49.267  -17.193  -32.291 1.00 56.56  ? 292  GLN F CD    1 
ATOM   18662 O OE1   . GLN F 1 292 ? -48.485  -17.479  -33.225 1.00 48.59  ? 292  GLN F OE1   1 
ATOM   18663 N NE2   . GLN F 1 292 ? -48.962  -16.446  -31.243 1.00 64.26  ? 292  GLN F NE2   1 
ATOM   18664 N N     . THR F 1 293 ? -54.512  -15.001  -33.189 1.00 23.26  ? 293  THR F N     1 
ATOM   18665 C CA    . THR F 1 293 ? -55.490  -13.971  -32.840 1.00 23.53  ? 293  THR F CA    1 
ATOM   18666 C C     . THR F 1 293 ? -56.807  -14.622  -32.424 1.00 24.26  ? 293  THR F C     1 
ATOM   18667 O O     . THR F 1 293 ? -57.359  -14.286  -31.380 1.00 28.35  ? 293  THR F O     1 
ATOM   18668 C CB    . THR F 1 293 ? -55.671  -12.984  -34.001 1.00 23.79  ? 293  THR F CB    1 
ATOM   18669 O OG1   . THR F 1 293 ? -54.480  -12.211  -34.083 1.00 23.33  ? 293  THR F OG1   1 
ATOM   18670 C CG2   . THR F 1 293 ? -56.862  -12.061  -33.809 1.00 20.34  ? 293  THR F CG2   1 
ATOM   18671 N N     . TYR F 1 294 ? -57.306  -15.565  -33.231 1.00 23.25  ? 294  TYR F N     1 
ATOM   18672 C CA    . TYR F 1 294 ? -58.566  -16.239  -32.953 1.00 22.92  ? 294  TYR F CA    1 
ATOM   18673 C C     . TYR F 1 294 ? -58.474  -17.034  -31.652 1.00 24.39  ? 294  TYR F C     1 
ATOM   18674 O O     . TYR F 1 294 ? -59.423  -17.043  -30.857 1.00 25.43  ? 294  TYR F O     1 
ATOM   18675 C CB    . TYR F 1 294 ? -59.026  -17.128  -34.119 1.00 22.18  ? 294  TYR F CB    1 
ATOM   18676 C CG    . TYR F 1 294 ? -59.674  -16.292  -35.215 1.00 22.52  ? 294  TYR F CG    1 
ATOM   18677 C CD1   . TYR F 1 294 ? -58.901  -15.504  -36.065 1.00 20.34  ? 294  TYR F CD1   1 
ATOM   18678 C CD2   . TYR F 1 294 ? -61.061  -16.293  -35.393 1.00 21.46  ? 294  TYR F CD2   1 
ATOM   18679 C CE1   . TYR F 1 294 ? -59.492  -14.726  -37.045 1.00 20.09  ? 294  TYR F CE1   1 
ATOM   18680 C CE2   . TYR F 1 294 ? -61.659  -15.529  -36.378 1.00 19.34  ? 294  TYR F CE2   1 
ATOM   18681 C CZ    . TYR F 1 294 ? -60.871  -14.745  -37.204 1.00 20.95  ? 294  TYR F CZ    1 
ATOM   18682 O OH    . TYR F 1 294 ? -61.456  -13.976  -38.178 1.00 20.66  ? 294  TYR F OH    1 
ATOM   18683 N N     . MET F 1 295 ? -57.330  -17.680  -31.424 1.00 23.63  ? 295  MET F N     1 
ATOM   18684 C CA    . MET F 1 295 ? -57.139  -18.439  -30.189 1.00 26.81  ? 295  MET F CA    1 
ATOM   18685 C C     . MET F 1 295 ? -57.161  -17.549  -28.946 1.00 25.03  ? 295  MET F C     1 
ATOM   18686 O O     . MET F 1 295 ? -57.795  -17.929  -27.955 1.00 25.05  ? 295  MET F O     1 
ATOM   18687 C CB    . MET F 1 295 ? -55.887  -19.316  -30.250 1.00 25.34  ? 295  MET F CB    1 
ATOM   18688 C CG    . MET F 1 295 ? -56.110  -20.495  -31.209 1.00 31.54  ? 295  MET F CG    1 
ATOM   18689 S SD    . MET F 1 295 ? -54.645  -21.539  -31.262 1.00 40.65  ? 295  MET F SD    1 
ATOM   18690 C CE    . MET F 1 295 ? -53.395  -20.455  -31.921 1.00 53.39  ? 295  MET F CE    1 
ATOM   18691 N N     . HIS F 1 296 ? -56.500  -16.378  -29.012 1.00 22.06  ? 296  HIS F N     1 
ATOM   18692 C CA    . HIS F 1 296 ? -56.524  -15.440  -27.895 1.00 26.54  ? 296  HIS F CA    1 
ATOM   18693 C C     . HIS F 1 296 ? -57.948  -14.996  -27.566 1.00 25.82  ? 296  HIS F C     1 
ATOM   18694 O O     . HIS F 1 296 ? -58.323  -15.019  -26.395 1.00 29.63  ? 296  HIS F O     1 
ATOM   18695 C CB    . HIS F 1 296 ? -55.516  -14.297  -28.065 1.00 27.57  ? 296  HIS F CB    1 
ATOM   18696 C CG    . HIS F 1 296 ? -54.108  -14.746  -27.834 1.00 38.01  ? 296  HIS F CG    1 
ATOM   18697 N ND1   . HIS F 1 296 ? -53.100  -14.526  -28.751 1.00 47.54  ? 296  HIS F ND1   1 
ATOM   18698 C CD2   . HIS F 1 296 ? -53.544  -15.452  -26.849 1.00 44.71  ? 296  HIS F CD2   1 
ATOM   18699 C CE1   . HIS F 1 296 ? -51.964  -15.070  -28.332 1.00 44.02  ? 296  HIS F CE1   1 
ATOM   18700 N NE2   . HIS F 1 296 ? -52.218  -15.622  -27.177 1.00 51.08  ? 296  HIS F NE2   1 
ATOM   18701 N N     . LEU F 1 297 ? -58.728  -14.628  -28.598 1.00 26.91  ? 297  LEU F N     1 
ATOM   18702 C CA    . LEU F 1 297 ? -60.100  -14.178  -28.385 1.00 27.40  ? 297  LEU F CA    1 
ATOM   18703 C C     . LEU F 1 297 ? -60.939  -15.318  -27.811 1.00 25.41  ? 297  LEU F C     1 
ATOM   18704 O O     . LEU F 1 297 ? -61.630  -15.127  -26.814 1.00 29.60  ? 297  LEU F O     1 
ATOM   18705 C CB    . LEU F 1 297 ? -60.744  -13.559  -29.629 1.00 24.28  ? 297  LEU F CB    1 
ATOM   18706 C CG    . LEU F 1 297 ? -60.029  -12.318  -30.171 1.00 24.46  ? 297  LEU F CG    1 
ATOM   18707 C CD1   . LEU F 1 297 ? -60.459  -11.962  -31.593 1.00 20.88  ? 297  LEU F CD1   1 
ATOM   18708 C CD2   . LEU F 1 297 ? -60.288  -11.132  -29.243 1.00 22.90  ? 297  LEU F CD2   1 
ATOM   18709 N N     . LEU F 1 298 ? -60.856  -16.510  -28.412 1.00 23.46  ? 298  LEU F N     1 
ATOM   18710 C CA    . LEU F 1 298 ? -61.656  -17.616  -27.919 1.00 24.51  ? 298  LEU F CA    1 
ATOM   18711 C C     . LEU F 1 298 ? -61.288  -17.911  -26.461 1.00 23.22  ? 298  LEU F C     1 
ATOM   18712 O O     . LEU F 1 298 ? -62.154  -18.216  -25.640 1.00 22.58  ? 298  LEU F O     1 
ATOM   18713 C CB    . LEU F 1 298 ? -61.421  -18.833  -28.814 1.00 24.13  ? 298  LEU F CB    1 
ATOM   18714 C CG    . LEU F 1 298 ? -62.154  -20.106  -28.375 1.00 25.24  ? 298  LEU F CG    1 
ATOM   18715 C CD1   . LEU F 1 298 ? -63.649  -19.829  -28.311 1.00 22.18  ? 298  LEU F CD1   1 
ATOM   18716 C CD2   . LEU F 1 298 ? -61.880  -21.208  -29.365 1.00 33.85  ? 298  LEU F CD2   1 
ATOM   18717 N N     . GLY F 1 299 ? -59.982  -17.836  -26.162 1.00 22.79  ? 299  GLY F N     1 
ATOM   18718 C CA    . GLY F 1 299 ? -59.466  -18.139  -24.839 1.00 23.55  ? 299  GLY F CA    1 
ATOM   18719 C C     . GLY F 1 299 ? -60.049  -17.217  -23.769 1.00 26.27  ? 299  GLY F C     1 
ATOM   18720 O O     . GLY F 1 299 ? -60.323  -17.657  -22.651 1.00 25.49  ? 299  GLY F O     1 
ATOM   18721 N N     . ARG F 1 300 ? -60.272  -15.938  -24.113 1.00 24.06  ? 300  ARG F N     1 
ATOM   18722 C CA    . ARG F 1 300 ? -60.873  -15.041  -23.141 1.00 23.26  ? 300  ARG F CA    1 
ATOM   18723 C C     . ARG F 1 300 ? -62.297  -15.505  -22.863 1.00 25.16  ? 300  ARG F C     1 
ATOM   18724 O O     . ARG F 1 300 ? -62.723  -15.496  -21.715 1.00 27.95  ? 300  ARG F O     1 
ATOM   18725 C CB    . ARG F 1 300 ? -60.860  -13.588  -23.608 1.00 24.05  ? 300  ARG F CB    1 
ATOM   18726 C CG    . ARG F 1 300 ? -59.461  -12.983  -23.560 1.00 24.16  ? 300  ARG F CG    1 
ATOM   18727 C CD    . ARG F 1 300 ? -59.566  -11.729  -24.396 1.00 27.30  ? 300  ARG F CD    1 
ATOM   18728 N NE    . ARG F 1 300 ? -58.273  -11.049  -24.345 1.00 33.01  ? 300  ARG F NE    1 
ATOM   18729 C CZ    . ARG F 1 300 ? -57.828  -10.352  -23.303 1.00 33.39  ? 300  ARG F CZ    1 
ATOM   18730 N NH1   . ARG F 1 300 ? -58.600  -10.111  -22.255 1.00 30.35  ? 300  ARG F NH1   1 
ATOM   18731 N NH2   . ARG F 1 300 ? -56.622  -9.846   -23.379 1.00 30.99  ? 300  ARG F NH2   1 
ATOM   18732 N N     . TRP F 1 301 ? -63.016  -15.952  -23.907 1.00 22.07  ? 301  TRP F N     1 
ATOM   18733 C CA    . TRP F 1 301 ? -64.386  -16.382  -23.694 1.00 20.72  ? 301  TRP F CA    1 
ATOM   18734 C C     . TRP F 1 301 ? -64.431  -17.684  -22.892 1.00 23.40  ? 301  TRP F C     1 
ATOM   18735 O O     . TRP F 1 301 ? -65.255  -17.815  -21.990 1.00 27.13  ? 301  TRP F O     1 
ATOM   18736 C CB    . TRP F 1 301 ? -65.140  -16.501  -25.032 1.00 19.55  ? 301  TRP F CB    1 
ATOM   18737 C CG    . TRP F 1 301 ? -66.607  -16.780  -24.831 1.00 19.11  ? 301  TRP F CG    1 
ATOM   18738 C CD1   . TRP F 1 301 ? -67.581  -15.850  -24.647 1.00 18.01  ? 301  TRP F CD1   1 
ATOM   18739 C CD2   . TRP F 1 301 ? -67.264  -18.068  -24.773 1.00 18.97  ? 301  TRP F CD2   1 
ATOM   18740 N NE1   . TRP F 1 301 ? -68.799  -16.453  -24.487 1.00 17.30  ? 301  TRP F NE1   1 
ATOM   18741 C CE2   . TRP F 1 301 ? -68.636  -17.812  -24.531 1.00 18.78  ? 301  TRP F CE2   1 
ATOM   18742 C CE3   . TRP F 1 301 ? -66.830  -19.397  -24.893 1.00 20.34  ? 301  TRP F CE3   1 
ATOM   18743 C CZ2   . TRP F 1 301 ? -69.588  -18.832  -24.416 1.00 19.62  ? 301  TRP F CZ2   1 
ATOM   18744 C CZ3   . TRP F 1 301 ? -67.777  -20.411  -24.777 1.00 21.16  ? 301  TRP F CZ3   1 
ATOM   18745 C CH2   . TRP F 1 301 ? -69.130  -20.132  -24.536 1.00 19.16  ? 301  TRP F CH2   1 
ATOM   18746 N N     . THR F 1 302 ? -63.582  -18.666  -23.234 1.00 21.00  ? 302  THR F N     1 
ATOM   18747 C CA    . THR F 1 302 ? -63.710  -19.970  -22.593 1.00 22.12  ? 302  THR F CA    1 
ATOM   18748 C C     . THR F 1 302 ? -63.273  -19.863  -21.131 1.00 22.30  ? 302  THR F C     1 
ATOM   18749 O O     . THR F 1 302 ? -63.803  -20.566  -20.290 1.00 24.05  ? 302  THR F O     1 
ATOM   18750 C CB    . THR F 1 302 ? -62.965  -21.091  -23.332 1.00 20.25  ? 302  THR F CB    1 
ATOM   18751 O OG1   . THR F 1 302 ? -61.599  -20.696  -23.245 1.00 20.90  ? 302  THR F OG1   1 
ATOM   18752 C CG2   . THR F 1 302 ? -63.429  -21.267  -24.773 1.00 17.77  ? 302  THR F CG2   1 
ATOM   18753 N N     . ALA F 1 303 ? -62.317  -18.982  -20.810 1.00 22.18  ? 303  ALA F N     1 
ATOM   18754 C CA    . ALA F 1 303 ? -61.950  -18.785  -19.404 1.00 23.81  ? 303  ALA F CA    1 
ATOM   18755 C C     . ALA F 1 303 ? -63.165  -18.274  -18.613 1.00 27.30  ? 303  ALA F C     1 
ATOM   18756 O O     . ALA F 1 303 ? -63.451  -18.771  -17.525 1.00 32.27  ? 303  ALA F O     1 
ATOM   18757 C CB    . ALA F 1 303 ? -60.722  -17.884  -19.231 1.00 18.49  ? 303  ALA F CB    1 
ATOM   18758 N N     . MET F 1 304 ? -63.908  -17.323  -19.185 1.00 21.92  ? 304  MET F N     1 
ATOM   18759 C CA    . MET F 1 304 ? -65.109  -16.809  -18.547 1.00 22.37  ? 304  MET F CA    1 
ATOM   18760 C C     . MET F 1 304 ? -66.152  -17.929  -18.427 1.00 24.44  ? 304  MET F C     1 
ATOM   18761 O O     . MET F 1 304 ? -66.827  -18.034  -17.418 1.00 28.96  ? 304  MET F O     1 
ATOM   18762 C CB    . MET F 1 304 ? -65.589  -15.554  -19.309 1.00 20.19  ? 304  MET F CB    1 
ATOM   18763 C CG    . MET F 1 304 ? -66.951  -15.006  -18.929 1.00 21.85  ? 304  MET F CG    1 
ATOM   18764 S SD    . MET F 1 304 ? -68.395  -15.953  -19.467 1.00 29.11  ? 304  MET F SD    1 
ATOM   18765 C CE    . MET F 1 304 ? -68.372  -15.643  -21.233 1.00 20.23  ? 304  MET F CE    1 
ATOM   18766 N N     . ALA F 1 305 ? -66.287  -18.779  -19.455 1.00 24.53  ? 305  ALA F N     1 
ATOM   18767 C CA    . ALA F 1 305 ? -67.364  -19.764  -19.537 1.00 23.34  ? 305  ALA F CA    1 
ATOM   18768 C C     . ALA F 1 305 ? -67.029  -21.081  -18.825 1.00 23.12  ? 305  ALA F C     1 
ATOM   18769 O O     . ALA F 1 305 ? -67.866  -21.987  -18.821 1.00 27.80  ? 305  ALA F O     1 
ATOM   18770 C CB    . ALA F 1 305 ? -67.716  -20.045  -20.986 1.00 20.77  ? 305  ALA F CB    1 
ATOM   18771 N N     . ALA F 1 306 ? -65.818  -21.208  -18.256 1.00 23.54  ? 306  ALA F N     1 
ATOM   18772 C CA    . ALA F 1 306 ? -65.322  -22.448  -17.639 1.00 22.43  ? 306  ALA F CA    1 
ATOM   18773 C C     . ALA F 1 306 ? -66.336  -23.139  -16.710 1.00 26.46  ? 306  ALA F C     1 
ATOM   18774 O O     . ALA F 1 306 ? -66.422  -24.372  -16.710 1.00 30.17  ? 306  ALA F O     1 
ATOM   18775 C CB    . ALA F 1 306 ? -64.014  -22.224  -16.928 1.00 19.69  ? 306  ALA F CB    1 
ATOM   18776 N N     . PRO F 1 307 ? -67.136  -22.443  -15.859 1.00 26.98  ? 307  PRO F N     1 
ATOM   18777 C CA    . PRO F 1 307 ? -68.078  -23.155  -14.997 1.00 26.69  ? 307  PRO F CA    1 
ATOM   18778 C C     . PRO F 1 307 ? -69.102  -23.999  -15.757 1.00 32.08  ? 307  PRO F C     1 
ATOM   18779 O O     . PRO F 1 307 ? -69.666  -24.904  -15.169 1.00 31.42  ? 307  PRO F O     1 
ATOM   18780 C CB    . PRO F 1 307 ? -68.744  -22.084  -14.136 1.00 25.47  ? 307  PRO F CB    1 
ATOM   18781 C CG    . PRO F 1 307 ? -67.779  -20.913  -14.223 1.00 28.18  ? 307  PRO F CG    1 
ATOM   18782 C CD    . PRO F 1 307 ? -67.110  -20.992  -15.594 1.00 29.20  ? 307  PRO F CD    1 
ATOM   18783 N N     . VAL F 1 308 ? -69.339  -23.727  -17.056 1.00 25.84  ? 308  VAL F N     1 
ATOM   18784 C CA    . VAL F 1 308 ? -70.418  -24.416  -17.743 1.00 23.04  ? 308  VAL F CA    1 
ATOM   18785 C C     . VAL F 1 308 ? -69.933  -25.101  -19.028 1.00 25.22  ? 308  VAL F C     1 
ATOM   18786 O O     . VAL F 1 308 ? -70.580  -26.030  -19.506 1.00 24.86  ? 308  VAL F O     1 
ATOM   18787 C CB    . VAL F 1 308 ? -71.622  -23.495  -18.030 1.00 22.06  ? 308  VAL F CB    1 
ATOM   18788 C CG1   . VAL F 1 308 ? -71.263  -22.357  -18.967 1.00 19.47  ? 308  VAL F CG1   1 
ATOM   18789 C CG2   . VAL F 1 308 ? -72.819  -24.291  -18.563 1.00 21.04  ? 308  VAL F CG2   1 
ATOM   18790 N N     . LEU F 1 309 ? -68.809  -24.651  -19.599 1.00 25.69  ? 309  LEU F N     1 
ATOM   18791 C CA    . LEU F 1 309 ? -68.407  -25.139  -20.911 1.00 26.95  ? 309  LEU F CA    1 
ATOM   18792 C C     . LEU F 1 309 ? -68.216  -26.660  -20.928 1.00 28.10  ? 309  LEU F C     1 
ATOM   18793 O O     . LEU F 1 309 ? -68.536  -27.301  -21.925 1.00 30.73  ? 309  LEU F O     1 
ATOM   18794 C CB    . LEU F 1 309 ? -67.137  -24.414  -21.350 1.00 26.22  ? 309  LEU F CB    1 
ATOM   18795 C CG    . LEU F 1 309 ? -66.549  -24.844  -22.699 1.00 27.25  ? 309  LEU F CG    1 
ATOM   18796 C CD1   . LEU F 1 309 ? -67.556  -24.508  -23.815 1.00 22.94  ? 309  LEU F CD1   1 
ATOM   18797 C CD2   . LEU F 1 309 ? -65.220  -24.151  -22.930 1.00 20.17  ? 309  LEU F CD2   1 
ATOM   18798 N N     . TYR F 1 310 ? -67.652  -27.228  -19.850 1.00 28.00  ? 310  TYR F N     1 
ATOM   18799 C CA    . TYR F 1 310 ? -67.301  -28.649  -19.769 1.00 28.85  ? 310  TYR F CA    1 
ATOM   18800 C C     . TYR F 1 310 ? -68.477  -29.515  -19.304 1.00 30.28  ? 310  TYR F C     1 
ATOM   18801 O O     . TYR F 1 310 ? -68.818  -30.512  -19.956 1.00 32.19  ? 310  TYR F O     1 
ATOM   18802 C CB    . TYR F 1 310 ? -66.036  -28.834  -18.925 1.00 25.08  ? 310  TYR F CB    1 
ATOM   18803 C CG    . TYR F 1 310 ? -64.961  -27.918  -19.472 1.00 27.20  ? 310  TYR F CG    1 
ATOM   18804 C CD1   . TYR F 1 310 ? -64.411  -28.148  -20.744 1.00 26.70  ? 310  TYR F CD1   1 
ATOM   18805 C CD2   . TYR F 1 310 ? -64.570  -26.771  -18.781 1.00 25.35  ? 310  TYR F CD2   1 
ATOM   18806 C CE1   . TYR F 1 310 ? -63.483  -27.264  -21.284 1.00 25.72  ? 310  TYR F CE1   1 
ATOM   18807 C CE2   . TYR F 1 310 ? -63.626  -25.893  -19.306 1.00 22.64  ? 310  TYR F CE2   1 
ATOM   18808 C CZ    . TYR F 1 310 ? -63.081  -26.151  -20.552 1.00 25.07  ? 310  TYR F CZ    1 
ATOM   18809 O OH    . TYR F 1 310 ? -62.160  -25.289  -21.077 1.00 28.00  ? 310  TYR F OH    1 
ATOM   18810 N N     . LYS F 1 311 ? -69.119  -29.122  -18.191 1.00 28.44  ? 311  LYS F N     1 
ATOM   18811 C CA    . LYS F 1 311 ? -70.124  -29.969  -17.565 1.00 30.98  ? 311  LYS F CA    1 
ATOM   18812 C C     . LYS F 1 311 ? -71.536  -29.652  -18.035 1.00 30.49  ? 311  LYS F C     1 
ATOM   18813 O O     . LYS F 1 311 ? -72.425  -30.452  -17.785 1.00 29.97  ? 311  LYS F O     1 
ATOM   18814 C CB    . LYS F 1 311 ? -70.057  -29.805  -16.046 1.00 32.04  ? 311  LYS F CB    1 
ATOM   18815 C CG    . LYS F 1 311 ? -68.734  -30.200  -15.434 1.00 38.37  ? 311  LYS F CG    1 
ATOM   18816 C CD    . LYS F 1 311 ? -68.624  -31.726  -15.482 1.00 47.55  ? 311  LYS F CD    1 
ATOM   18817 C CE    . LYS F 1 311 ? -67.428  -32.248  -14.716 1.00 55.69  ? 311  LYS F CE    1 
ATOM   18818 N NZ    . LYS F 1 311 ? -67.568  -33.704  -14.723 1.00 45.53  ? 311  LYS F NZ    1 
ATOM   18819 N N     . GLY F 1 312 ? -71.753  -28.491  -18.687 1.00 30.97  ? 312  GLY F N     1 
ATOM   18820 C CA    . GLY F 1 312 ? -73.098  -28.091  -19.073 1.00 25.50  ? 312  GLY F CA    1 
ATOM   18821 C C     . GLY F 1 312 ? -73.693  -29.031  -20.120 1.00 26.44  ? 312  GLY F C     1 
ATOM   18822 O O     . GLY F 1 312 ? -73.001  -29.454  -21.040 1.00 25.00  ? 312  GLY F O     1 
ATOM   18823 N N     . ARG F 1 313 ? -74.988  -29.339  -19.976 1.00 24.37  ? 313  ARG F N     1 
ATOM   18824 C CA    . ARG F 1 313 ? -75.672  -30.244  -20.878 1.00 26.78  ? 313  ARG F CA    1 
ATOM   18825 C C     . ARG F 1 313 ? -77.009  -29.633  -21.279 1.00 26.30  ? 313  ARG F C     1 
ATOM   18826 O O     . ARG F 1 313 ? -77.598  -28.841  -20.538 1.00 24.48  ? 313  ARG F O     1 
ATOM   18827 C CB    . ARG F 1 313 ? -75.950  -31.602  -20.207 1.00 25.49  ? 313  ARG F CB    1 
ATOM   18828 C CG    . ARG F 1 313 ? -74.691  -32.389  -19.864 1.00 25.13  ? 313  ARG F CG    1 
ATOM   18829 C CD    . ARG F 1 313 ? -73.975  -32.839  -21.162 1.00 28.24  ? 313  ARG F CD    1 
ATOM   18830 N NE    . ARG F 1 313 ? -72.748  -33.609  -20.914 1.00 27.73  ? 313  ARG F NE    1 
ATOM   18831 C CZ    . ARG F 1 313 ? -71.561  -33.153  -20.551 1.00 28.34  ? 313  ARG F CZ    1 
ATOM   18832 N NH1   . ARG F 1 313 ? -71.288  -31.846  -20.565 1.00 30.23  ? 313  ARG F NH1   1 
ATOM   18833 N NH2   . ARG F 1 313 ? -70.608  -34.026  -20.229 1.00 25.50  ? 313  ARG F NH2   1 
ATOM   18834 N N     . PRO F 1 314 ? -77.528  -29.985  -22.472 1.00 28.53  ? 314  PRO F N     1 
ATOM   18835 C CA    . PRO F 1 314 ? -78.844  -29.509  -22.895 1.00 32.45  ? 314  PRO F CA    1 
ATOM   18836 C C     . PRO F 1 314 ? -79.924  -29.932  -21.906 1.00 32.29  ? 314  PRO F C     1 
ATOM   18837 O O     . PRO F 1 314 ? -79.781  -30.946  -21.247 1.00 34.78  ? 314  PRO F O     1 
ATOM   18838 C CB    . PRO F 1 314 ? -79.101  -30.221  -24.223 1.00 28.48  ? 314  PRO F CB    1 
ATOM   18839 C CG    . PRO F 1 314 ? -77.712  -30.674  -24.671 1.00 28.75  ? 314  PRO F CG    1 
ATOM   18840 C CD    . PRO F 1 314 ? -76.880  -30.885  -23.446 1.00 27.01  ? 314  PRO F CD    1 
ATOM   18841 N N     . VAL F 1 315 ? -81.014  -29.182  -21.834 1.00 33.28  ? 315  VAL F N     1 
ATOM   18842 C CA    . VAL F 1 315 ? -82.082  -29.473  -20.904 1.00 34.20  ? 315  VAL F CA    1 
ATOM   18843 C C     . VAL F 1 315 ? -83.362  -28.969  -21.563 1.00 36.01  ? 315  VAL F C     1 
ATOM   18844 O O     . VAL F 1 315 ? -83.298  -28.065  -22.377 1.00 35.48  ? 315  VAL F O     1 
ATOM   18845 C CB    . VAL F 1 315 ? -81.671  -28.696  -19.629 1.00 35.83  ? 315  VAL F CB    1 
ATOM   18846 C CG1   . VAL F 1 315 ? -81.738  -27.165  -19.766 1.00 30.06  ? 315  VAL F CG1   1 
ATOM   18847 C CG2   . VAL F 1 315 ? -82.381  -29.192  -18.371 1.00 31.46  ? 315  VAL F CG2   1 
ATOM   18848 N N     . PRO F 1 316 ? -84.560  -29.550  -21.310 1.00 39.58  ? 316  PRO F N     1 
ATOM   18849 C CA    . PRO F 1 316 ? -85.782  -29.078  -21.968 1.00 39.46  ? 316  PRO F CA    1 
ATOM   18850 C C     . PRO F 1 316 ? -86.291  -27.738  -21.398 1.00 40.80  ? 316  PRO F C     1 
ATOM   18851 O O     . PRO F 1 316 ? -87.306  -27.674  -20.705 1.00 43.62  ? 316  PRO F O     1 
ATOM   18852 C CB    . PRO F 1 316 ? -86.723  -30.285  -21.794 1.00 32.46  ? 316  PRO F CB    1 
ATOM   18853 C CG    . PRO F 1 316 ? -86.297  -30.817  -20.411 1.00 29.21  ? 316  PRO F CG    1 
ATOM   18854 C CD    . PRO F 1 316 ? -84.809  -30.644  -20.347 1.00 31.41  ? 316  PRO F CD    1 
ATOM   18855 N N     . VAL F 1 317 ? -85.527  -26.670  -21.612 1.00 37.22  ? 317  VAL F N     1 
ATOM   18856 C CA    . VAL F 1 317 ? -85.911  -25.329  -21.217 1.00 35.19  ? 317  VAL F CA    1 
ATOM   18857 C C     . VAL F 1 317 ? -85.782  -24.479  -22.470 1.00 36.08  ? 317  VAL F C     1 
ATOM   18858 O O     . VAL F 1 317 ? -84.704  -24.459  -23.050 1.00 38.07  ? 317  VAL F O     1 
ATOM   18859 C CB    . VAL F 1 317 ? -85.044  -24.745  -20.082 1.00 31.29  ? 317  VAL F CB    1 
ATOM   18860 C CG1   . VAL F 1 317 ? -85.419  -23.296  -19.772 1.00 29.56  ? 317  VAL F CG1   1 
ATOM   18861 C CG2   . VAL F 1 317 ? -85.123  -25.607  -18.824 1.00 27.85  ? 317  VAL F CG2   1 
ATOM   18862 N N     . THR F 1 318 ? -86.868  -23.838  -22.903 1.00 33.35  ? 318  THR F N     1 
ATOM   18863 C CA    . THR F 1 318 ? -86.769  -23.062  -24.126 1.00 31.07  ? 318  THR F CA    1 
ATOM   18864 C C     . THR F 1 318 ? -86.804  -21.565  -23.822 1.00 29.93  ? 318  THR F C     1 
ATOM   18865 O O     . THR F 1 318 ? -87.167  -21.123  -22.731 1.00 31.15  ? 318  THR F O     1 
ATOM   18866 C CB    . THR F 1 318 ? -87.847  -23.484  -25.129 1.00 36.16  ? 318  THR F CB    1 
ATOM   18867 O OG1   . THR F 1 318 ? -89.104  -23.180  -24.521 1.00 31.80  ? 318  THR F OG1   1 
ATOM   18868 C CG2   . THR F 1 318 ? -87.685  -24.932  -25.573 1.00 32.67  ? 318  THR F CG2   1 
ATOM   18869 N N     . SER F 1 319 ? -86.414  -20.773  -24.820 1.00 25.79  ? 319  SER F N     1 
ATOM   18870 C CA    . SER F 1 319 ? -86.394  -19.339  -24.668 1.00 26.68  ? 319  SER F CA    1 
ATOM   18871 C C     . SER F 1 319 ? -87.663  -18.760  -25.291 1.00 27.79  ? 319  SER F C     1 
ATOM   18872 O O     . SER F 1 319 ? -88.305  -19.393  -26.107 1.00 29.69  ? 319  SER F O     1 
ATOM   18873 C CB    . SER F 1 319 ? -85.127  -18.767  -25.233 1.00 28.81  ? 319  SER F CB    1 
ATOM   18874 O OG    . SER F 1 319 ? -85.149  -18.807  -26.649 1.00 32.39  ? 319  SER F OG    1 
ATOM   18875 N N     . ALA F 1 320 ? -88.046  -17.563  -24.877 1.00 26.02  ? 320  ALA F N     1 
ATOM   18876 C CA    . ALA F 1 320 ? -89.207  -16.874  -25.415 1.00 30.36  ? 320  ALA F CA    1 
ATOM   18877 C C     . ALA F 1 320 ? -89.053  -16.604  -26.922 1.00 31.00  ? 320  ALA F C     1 
ATOM   18878 O O     . ALA F 1 320 ? -87.951  -16.568  -27.473 1.00 30.06  ? 320  ALA F O     1 
ATOM   18879 C CB    . ALA F 1 320 ? -89.348  -15.546  -24.689 1.00 31.65  ? 320  ALA F CB    1 
ATOM   18880 N N     . HIS F 1 321 ? -90.203  -16.354  -27.557 1.00 28.52  ? 321  HIS F N     1 
ATOM   18881 C CA    . HIS F 1 321 ? -90.340  -15.984  -28.945 1.00 26.87  ? 321  HIS F CA    1 
ATOM   18882 C C     . HIS F 1 321 ? -89.331  -14.916  -29.351 1.00 30.53  ? 321  HIS F C     1 
ATOM   18883 O O     . HIS F 1 321 ? -89.250  -13.864  -28.716 1.00 31.22  ? 321  HIS F O     1 
ATOM   18884 C CB    . HIS F 1 321 ? -91.784  -15.563  -29.218 1.00 28.27  ? 321  HIS F CB    1 
ATOM   18885 C CG    . HIS F 1 321 ? -91.966  -15.227  -30.655 1.00 36.37  ? 321  HIS F CG    1 
ATOM   18886 N ND1   . HIS F 1 321 ? -91.998  -13.924  -31.102 1.00 38.02  ? 321  HIS F ND1   1 
ATOM   18887 C CD2   . HIS F 1 321 ? -92.133  -16.005  -31.743 1.00 36.85  ? 321  HIS F CD2   1 
ATOM   18888 C CE1   . HIS F 1 321 ? -92.135  -13.926  -32.418 1.00 38.31  ? 321  HIS F CE1   1 
ATOM   18889 N NE2   . HIS F 1 321 ? -92.241  -15.171  -32.816 1.00 37.21  ? 321  HIS F NE2   1 
ATOM   18890 N N     . GLY F 1 322 ? -88.570  -15.203  -30.422 1.00 31.29  ? 322  GLY F N     1 
ATOM   18891 C CA    . GLY F 1 322 ? -87.762  -14.183  -31.072 1.00 33.91  ? 322  GLY F CA    1 
ATOM   18892 C C     . GLY F 1 322 ? -86.375  -13.971  -30.464 1.00 39.17  ? 322  GLY F C     1 
ATOM   18893 O O     . GLY F 1 322 ? -85.718  -12.986  -30.800 1.00 41.08  ? 322  GLY F O     1 
ATOM   18894 N N     . THR F 1 323 ? -85.930  -14.875  -29.570 1.00 32.00  ? 323  THR F N     1 
ATOM   18895 C CA    . THR F 1 323 ? -84.580  -14.756  -29.032 1.00 28.76  ? 323  THR F CA    1 
ATOM   18896 C C     . THR F 1 323 ? -83.852  -16.035  -29.405 1.00 32.22  ? 323  THR F C     1 
ATOM   18897 O O     . THR F 1 323 ? -84.494  -17.016  -29.733 1.00 31.81  ? 323  THR F O     1 
ATOM   18898 C CB    . THR F 1 323 ? -84.556  -14.489  -27.519 1.00 28.15  ? 323  THR F CB    1 
ATOM   18899 O OG1   . THR F 1 323 ? -84.766  -15.736  -26.850 1.00 26.25  ? 323  THR F OG1   1 
ATOM   18900 C CG2   . THR F 1 323 ? -85.586  -13.464  -27.066 1.00 22.92  ? 323  THR F CG2   1 
ATOM   18901 N N     . ARG F 1 324 ? -82.523  -16.008  -29.333 1.00 32.46  ? 324  ARG F N     1 
ATOM   18902 C CA    . ARG F 1 324 ? -81.701  -17.171  -29.608 1.00 28.82  ? 324  ARG F CA    1 
ATOM   18903 C C     . ARG F 1 324 ? -81.067  -17.632  -28.297 1.00 26.90  ? 324  ARG F C     1 
ATOM   18904 O O     . ARG F 1 324 ? -80.120  -18.404  -28.314 1.00 30.20  ? 324  ARG F O     1 
ATOM   18905 C CB    . ARG F 1 324 ? -80.574  -16.767  -30.577 1.00 28.54  ? 324  ARG F CB    1 
ATOM   18906 C CG    . ARG F 1 324 ? -81.053  -16.143  -31.880 1.00 28.52  ? 324  ARG F CG    1 
ATOM   18907 C CD    . ARG F 1 324 ? -79.961  -15.897  -32.907 1.00 29.74  ? 324  ARG F CD    1 
ATOM   18908 N NE    . ARG F 1 324 ? -78.992  -14.866  -32.508 1.00 29.85  ? 324  ARG F NE    1 
ATOM   18909 C CZ    . ARG F 1 324 ? -77.668  -14.912  -32.698 1.00 28.98  ? 324  ARG F CZ    1 
ATOM   18910 N NH1   . ARG F 1 324 ? -77.094  -16.001  -33.184 1.00 30.30  ? 324  ARG F NH1   1 
ATOM   18911 N NH2   . ARG F 1 324 ? -76.915  -13.875  -32.400 1.00 23.01  ? 324  ARG F NH2   1 
ATOM   18912 N N     . ASP F 1 325 ? -81.585  -17.168  -27.155 1.00 25.35  ? 325  ASP F N     1 
ATOM   18913 C CA    . ASP F 1 325 ? -81.035  -17.548  -25.851 1.00 25.67  ? 325  ASP F CA    1 
ATOM   18914 C C     . ASP F 1 325 ? -81.276  -19.050  -25.609 1.00 26.21  ? 325  ASP F C     1 
ATOM   18915 O O     . ASP F 1 325 ? -82.210  -19.632  -26.170 1.00 24.94  ? 325  ASP F O     1 
ATOM   18916 C CB    . ASP F 1 325 ? -81.669  -16.663  -24.788 1.00 24.72  ? 325  ASP F CB    1 
ATOM   18917 C CG    . ASP F 1 325 ? -81.548  -15.159  -25.040 1.00 27.51  ? 325  ASP F CG    1 
ATOM   18918 O OD1   . ASP F 1 325 ? -80.614  -14.726  -25.799 1.00 29.10  ? 325  ASP F OD1   1 
ATOM   18919 O OD2   . ASP F 1 325 ? -82.385  -14.407  -24.485 1.00 29.17  ? 325  ASP F OD2   1 
ATOM   18920 N N     . PHE F 1 326 ? -80.464  -19.677  -24.749 1.00 24.03  ? 326  PHE F N     1 
ATOM   18921 C CA    . PHE F 1 326 ? -80.690  -21.080  -24.411 1.00 24.16  ? 326  PHE F CA    1 
ATOM   18922 C C     . PHE F 1 326 ? -80.125  -21.358  -23.012 1.00 25.70  ? 326  PHE F C     1 
ATOM   18923 O O     . PHE F 1 326 ? -79.467  -20.483  -22.422 1.00 23.38  ? 326  PHE F O     1 
ATOM   18924 C CB    . PHE F 1 326 ? -80.068  -22.014  -25.463 1.00 20.77  ? 326  PHE F CB    1 
ATOM   18925 C CG    . PHE F 1 326 ? -78.553  -21.898  -25.604 1.00 23.26  ? 326  PHE F CG    1 
ATOM   18926 C CD1   . PHE F 1 326 ? -77.687  -22.667  -24.808 1.00 22.94  ? 326  PHE F CD1   1 
ATOM   18927 C CD2   . PHE F 1 326 ? -77.987  -21.022  -26.540 1.00 22.25  ? 326  PHE F CD2   1 
ATOM   18928 C CE1   . PHE F 1 326 ? -76.300  -22.567  -24.960 1.00 24.01  ? 326  PHE F CE1   1 
ATOM   18929 C CE2   . PHE F 1 326 ? -76.594  -20.909  -26.661 1.00 22.03  ? 326  PHE F CE2   1 
ATOM   18930 C CZ    . PHE F 1 326 ? -75.757  -21.693  -25.878 1.00 21.76  ? 326  PHE F CZ    1 
ATOM   18931 N N     . VAL F 1 327 ? -80.377  -22.577  -22.501 1.00 23.66  ? 327  VAL F N     1 
ATOM   18932 C CA    . VAL F 1 327 ? -79.987  -22.937  -21.145 1.00 24.79  ? 327  VAL F CA    1 
ATOM   18933 C C     . VAL F 1 327 ? -79.097  -24.182  -21.133 1.00 24.82  ? 327  VAL F C     1 
ATOM   18934 O O     . VAL F 1 327 ? -79.334  -25.119  -21.887 1.00 23.84  ? 327  VAL F O     1 
ATOM   18935 C CB    . VAL F 1 327 ? -81.280  -23.183  -20.342 1.00 25.09  ? 327  VAL F CB    1 
ATOM   18936 C CG1   . VAL F 1 327 ? -80.989  -23.517  -18.872 1.00 23.98  ? 327  VAL F CG1   1 
ATOM   18937 C CG2   . VAL F 1 327 ? -82.202  -21.971  -20.454 1.00 24.04  ? 327  VAL F CG2   1 
ATOM   18938 N N     . LEU F 1 328 ? -78.081  -24.192  -20.255 1.00 25.17  ? 328  LEU F N     1 
ATOM   18939 C CA    . LEU F 1 328 ? -77.285  -25.389  -20.006 1.00 27.03  ? 328  LEU F CA    1 
ATOM   18940 C C     . LEU F 1 328 ? -77.406  -25.789  -18.533 1.00 29.89  ? 328  LEU F C     1 
ATOM   18941 O O     . LEU F 1 328 ? -77.475  -24.932  -17.648 1.00 28.55  ? 328  LEU F O     1 
ATOM   18942 C CB    . LEU F 1 328 ? -75.828  -25.148  -20.409 1.00 24.88  ? 328  LEU F CB    1 
ATOM   18943 C CG    . LEU F 1 328 ? -75.560  -24.937  -21.908 1.00 26.04  ? 328  LEU F CG    1 
ATOM   18944 C CD1   . LEU F 1 328 ? -74.136  -24.435  -22.194 1.00 23.86  ? 328  LEU F CD1   1 
ATOM   18945 C CD2   . LEU F 1 328 ? -75.899  -26.251  -22.649 1.00 22.54  ? 328  LEU F CD2   1 
ATOM   18946 N N     . HIS F 1 329 ? -77.437  -27.103  -18.288 1.00 32.65  ? 329  HIS F N     1 
ATOM   18947 C CA    . HIS F 1 329 ? -77.646  -27.668  -16.957 1.00 32.94  ? 329  HIS F CA    1 
ATOM   18948 C C     . HIS F 1 329 ? -76.359  -28.355  -16.480 1.00 32.27  ? 329  HIS F C     1 
ATOM   18949 O O     . HIS F 1 329 ? -75.740  -29.122  -17.219 1.00 33.76  ? 329  HIS F O     1 
ATOM   18950 C CB    . HIS F 1 329 ? -78.841  -28.627  -17.036 1.00 29.20  ? 329  HIS F CB    1 
ATOM   18951 C CG    . HIS F 1 329 ? -79.055  -29.410  -15.791 1.00 38.24  ? 329  HIS F CG    1 
ATOM   18952 N ND1   . HIS F 1 329 ? -79.692  -28.891  -14.676 1.00 38.03  ? 329  HIS F ND1   1 
ATOM   18953 C CD2   . HIS F 1 329 ? -78.720  -30.677  -15.478 1.00 37.54  ? 329  HIS F CD2   1 
ATOM   18954 C CE1   . HIS F 1 329 ? -79.733  -29.807  -13.716 1.00 35.16  ? 329  HIS F CE1   1 
ATOM   18955 N NE2   . HIS F 1 329 ? -79.147  -30.895  -14.180 1.00 42.54  ? 329  HIS F NE2   1 
ATOM   18956 N N     . THR F 1 330 ? -75.925  -28.048  -15.257 1.00 32.49  ? 330  THR F N     1 
ATOM   18957 C CA    . THR F 1 330 ? -74.986  -28.910  -14.546 1.00 35.98  ? 330  THR F CA    1 
ATOM   18958 C C     . THR F 1 330 ? -75.720  -29.454  -13.326 1.00 39.96  ? 330  THR F C     1 
ATOM   18959 O O     . THR F 1 330 ? -76.874  -29.106  -13.098 1.00 40.54  ? 330  THR F O     1 
ATOM   18960 C CB    . THR F 1 330 ? -73.696  -28.197  -14.151 1.00 33.61  ? 330  THR F CB    1 
ATOM   18961 O OG1   . THR F 1 330 ? -74.082  -27.259  -13.147 1.00 35.02  ? 330  THR F OG1   1 
ATOM   18962 C CG2   . THR F 1 330 ? -73.018  -27.533  -15.335 1.00 29.25  ? 330  THR F CG2   1 
ATOM   18963 N N     . SER F 1 331 ? -75.073  -30.316  -12.538 1.00 47.39  ? 331  SER F N     1 
ATOM   18964 C CA    . SER F 1 331 ? -75.839  -30.918  -11.451 1.00 53.81  ? 331  SER F CA    1 
ATOM   18965 C C     . SER F 1 331 ? -76.133  -29.891  -10.358 1.00 47.22  ? 331  SER F C     1 
ATOM   18966 O O     . SER F 1 331 ? -77.114  -30.048  -9.665  1.00 43.87  ? 331  SER F O     1 
ATOM   18967 C CB    . SER F 1 331 ? -75.208  -32.171  -10.902 1.00 45.82  ? 331  SER F CB    1 
ATOM   18968 O OG    . SER F 1 331 ? -73.932  -31.792  -10.402 1.00 48.74  ? 331  SER F OG    1 
ATOM   18969 N N     . LYS F 1 332 ? -75.322  -28.826  -10.239 1.00 46.96  ? 332  LYS F N     1 
ATOM   18970 C CA    . LYS F 1 332 ? -75.518  -27.820  -9.204  1.00 49.93  ? 332  LYS F CA    1 
ATOM   18971 C C     . LYS F 1 332 ? -76.246  -26.557  -9.687  1.00 49.46  ? 332  LYS F C     1 
ATOM   18972 O O     . LYS F 1 332 ? -76.790  -25.838  -8.855  1.00 42.54  ? 332  LYS F O     1 
ATOM   18973 C CB    . LYS F 1 332 ? -74.161  -27.529  -8.555  1.00 58.52  ? 332  LYS F CB    1 
ATOM   18974 C CG    . LYS F 1 332 ? -73.971  -28.455  -7.367  1.00 79.47  ? 332  LYS F CG    1 
ATOM   18975 C CD    . LYS F 1 332 ? -72.572  -28.685  -6.820  1.00 94.23  ? 332  LYS F CD    1 
ATOM   18976 C CE    . LYS F 1 332 ? -72.744  -29.478  -5.563  1.00 99.14  ? 332  LYS F CE    1 
ATOM   18977 N NZ    . LYS F 1 332 ? -71.432  -29.653  -4.949  1.00 96.76  ? 332  LYS F NZ    1 
ATOM   18978 N N     . HIS F 1 333 ? -76.241  -26.255  -10.998 1.00 45.53  ? 333  HIS F N     1 
ATOM   18979 C CA    . HIS F 1 333 ? -76.737  -24.965  -11.465 1.00 37.38  ? 333  HIS F CA    1 
ATOM   18980 C C     . HIS F 1 333 ? -77.334  -25.066  -12.864 1.00 36.18  ? 333  HIS F C     1 
ATOM   18981 O O     . HIS F 1 333 ? -77.029  -25.985  -13.629 1.00 39.30  ? 333  HIS F O     1 
ATOM   18982 C CB    . HIS F 1 333 ? -75.601  -23.939  -11.535 1.00 40.53  ? 333  HIS F CB    1 
ATOM   18983 C CG    . HIS F 1 333 ? -74.887  -23.680  -10.257 1.00 42.06  ? 333  HIS F CG    1 
ATOM   18984 N ND1   . HIS F 1 333 ? -75.429  -22.910  -9.249  1.00 47.98  ? 333  HIS F ND1   1 
ATOM   18985 C CD2   . HIS F 1 333 ? -73.684  -24.071  -9.819  1.00 41.36  ? 333  HIS F CD2   1 
ATOM   18986 C CE1   . HIS F 1 333 ? -74.574  -22.842  -8.230  1.00 46.30  ? 333  HIS F CE1   1 
ATOM   18987 N NE2   . HIS F 1 333 ? -73.498  -23.535  -8.564  1.00 48.59  ? 333  HIS F NE2   1 
ATOM   18988 N N     . ASP F 1 334 ? -78.197  -24.108  -13.196 1.00 32.17  ? 334  ASP F N     1 
ATOM   18989 C CA    . ASP F 1 334 ? -78.531  -23.841  -14.583 1.00 30.02  ? 334  ASP F CA    1 
ATOM   18990 C C     . ASP F 1 334 ? -77.820  -22.568  -15.022 1.00 31.38  ? 334  ASP F C     1 
ATOM   18991 O O     . ASP F 1 334 ? -77.485  -21.727  -14.182 1.00 31.95  ? 334  ASP F O     1 
ATOM   18992 C CB    . ASP F 1 334 ? -80.031  -23.850  -14.821 1.00 28.73  ? 334  ASP F CB    1 
ATOM   18993 C CG    . ASP F 1 334 ? -80.658  -25.230  -14.675 1.00 34.11  ? 334  ASP F CG    1 
ATOM   18994 O OD1   . ASP F 1 334 ? -80.033  -26.225  -15.090 1.00 40.57  ? 334  ASP F OD1   1 
ATOM   18995 O OD2   . ASP F 1 334 ? -81.744  -25.323  -14.111 1.00 37.97  ? 334  ASP F OD2   1 
ATOM   18996 N N     . PHE F 1 335 ? -77.560  -22.456  -16.335 1.00 28.36  ? 335  PHE F N     1 
ATOM   18997 C CA    . PHE F 1 335 ? -76.886  -21.286  -16.880 1.00 25.53  ? 335  PHE F CA    1 
ATOM   18998 C C     . PHE F 1 335 ? -77.693  -20.780  -18.066 1.00 26.39  ? 335  PHE F C     1 
ATOM   18999 O O     . PHE F 1 335 ? -78.075  -21.568  -18.944 1.00 26.95  ? 335  PHE F O     1 
ATOM   19000 C CB    . PHE F 1 335 ? -75.471  -21.686  -17.303 1.00 24.75  ? 335  PHE F CB    1 
ATOM   19001 C CG    . PHE F 1 335 ? -74.552  -22.124  -16.174 1.00 24.24  ? 335  PHE F CG    1 
ATOM   19002 C CD1   . PHE F 1 335 ? -74.584  -23.434  -15.695 1.00 22.56  ? 335  PHE F CD1   1 
ATOM   19003 C CD2   . PHE F 1 335 ? -73.654  -21.223  -15.601 1.00 22.35  ? 335  PHE F CD2   1 
ATOM   19004 C CE1   . PHE F 1 335 ? -73.732  -23.823  -14.659 1.00 25.10  ? 335  PHE F CE1   1 
ATOM   19005 C CE2   . PHE F 1 335 ? -72.797  -21.621  -14.572 1.00 22.85  ? 335  PHE F CE2   1 
ATOM   19006 C CZ    . PHE F 1 335 ? -72.835  -22.929  -14.093 1.00 23.12  ? 335  PHE F CZ    1 
ATOM   19007 N N     . LEU F 1 336 ? -77.988  -19.477  -18.047 1.00 25.12  ? 336  LEU F N     1 
ATOM   19008 C CA    . LEU F 1 336 ? -78.648  -18.791  -19.146 1.00 25.73  ? 336  LEU F CA    1 
ATOM   19009 C C     . LEU F 1 336 ? -77.554  -18.265  -20.061 1.00 25.70  ? 336  LEU F C     1 
ATOM   19010 O O     . LEU F 1 336 ? -76.679  -17.523  -19.619 1.00 29.77  ? 336  LEU F O     1 
ATOM   19011 C CB    . LEU F 1 336 ? -79.529  -17.657  -18.621 1.00 23.84  ? 336  LEU F CB    1 
ATOM   19012 C CG    . LEU F 1 336 ? -80.520  -18.050  -17.519 1.00 26.21  ? 336  LEU F CG    1 
ATOM   19013 C CD1   . LEU F 1 336 ? -81.245  -16.817  -16.976 1.00 22.79  ? 336  LEU F CD1   1 
ATOM   19014 C CD2   . LEU F 1 336 ? -81.509  -19.091  -18.042 1.00 26.68  ? 336  LEU F CD2   1 
ATOM   19015 N N     . CYS F 1 337 ? -77.595  -18.700  -21.323 1.00 25.24  ? 337  CYS F N     1 
ATOM   19016 C CA    . CYS F 1 337 ? -76.674  -18.239  -22.351 1.00 25.89  ? 337  CYS F CA    1 
ATOM   19017 C C     . CYS F 1 337 ? -77.444  -17.235  -23.203 1.00 24.27  ? 337  CYS F C     1 
ATOM   19018 O O     . CYS F 1 337 ? -78.412  -17.596  -23.868 1.00 25.34  ? 337  CYS F O     1 
ATOM   19019 C CB    . CYS F 1 337 ? -76.155  -19.424  -23.169 1.00 28.35  ? 337  CYS F CB    1 
ATOM   19020 S SG    . CYS F 1 337 ? -75.252  -20.625  -22.145 1.00 29.31  ? 337  CYS F SG    1 
ATOM   19021 N N     . ILE F 1 338 ? -77.023  -15.973  -23.139 1.00 21.62  ? 338  ILE F N     1 
ATOM   19022 C CA    . ILE F 1 338 ? -77.858  -14.909  -23.657 1.00 23.68  ? 338  ILE F CA    1 
ATOM   19023 C C     . ILE F 1 338 ? -77.122  -14.202  -24.788 1.00 24.08  ? 338  ILE F C     1 
ATOM   19024 O O     . ILE F 1 338 ? -75.959  -13.813  -24.626 1.00 24.94  ? 338  ILE F O     1 
ATOM   19025 C CB    . ILE F 1 338 ? -78.288  -13.991  -22.496 1.00 24.16  ? 338  ILE F CB    1 
ATOM   19026 C CG1   . ILE F 1 338 ? -79.276  -14.804  -21.616 1.00 22.01  ? 338  ILE F CG1   1 
ATOM   19027 C CG2   . ILE F 1 338 ? -78.943  -12.717  -23.041 1.00 19.05  ? 338  ILE F CG2   1 
ATOM   19028 C CD1   . ILE F 1 338 ? -79.708  -14.084  -20.359 1.00 24.10  ? 338  ILE F CD1   1 
ATOM   19029 N N     . LEU F 1 339 ? -77.796  -14.100  -25.946 1.00 22.98  ? 339  LEU F N     1 
ATOM   19030 C CA    . LEU F 1 339 ? -77.208  -13.561  -27.178 1.00 22.99  ? 339  LEU F CA    1 
ATOM   19031 C C     . LEU F 1 339 ? -77.820  -12.198  -27.514 1.00 22.02  ? 339  LEU F C     1 
ATOM   19032 O O     . LEU F 1 339 ? -78.861  -11.813  -26.946 1.00 21.00  ? 339  LEU F O     1 
ATOM   19033 C CB    . LEU F 1 339 ? -77.370  -14.560  -28.331 1.00 21.55  ? 339  LEU F CB    1 
ATOM   19034 C CG    . LEU F 1 339 ? -76.421  -15.765  -28.290 1.00 21.80  ? 339  LEU F CG    1 
ATOM   19035 C CD1   . LEU F 1 339 ? -76.812  -16.803  -27.230 1.00 21.16  ? 339  LEU F CD1   1 
ATOM   19036 C CD2   . LEU F 1 339 ? -76.278  -16.452  -29.662 1.00 24.81  ? 339  LEU F CD2   1 
ATOM   19037 N N     . ASP F 1 340 ? -77.155  -11.467  -28.433 1.00 21.97  ? 340  ASP F N     1 
ATOM   19038 C CA    . ASP F 1 340 ? -77.721  -10.229  -28.981 1.00 23.24  ? 340  ASP F CA    1 
ATOM   19039 C C     . ASP F 1 340 ? -77.852  -9.161   -27.909 1.00 23.12  ? 340  ASP F C     1 
ATOM   19040 O O     . ASP F 1 340 ? -78.832  -8.450   -27.896 1.00 25.51  ? 340  ASP F O     1 
ATOM   19041 C CB    . ASP F 1 340 ? -79.050  -10.476  -29.696 1.00 20.06  ? 340  ASP F CB    1 
ATOM   19042 C CG    . ASP F 1 340 ? -78.927  -11.584  -30.749 1.00 26.19  ? 340  ASP F CG    1 
ATOM   19043 O OD1   . ASP F 1 340 ? -78.048  -11.456  -31.633 1.00 30.08  ? 340  ASP F OD1   1 
ATOM   19044 O OD2   . ASP F 1 340 ? -79.642  -12.608  -30.643 1.00 24.85  ? 340  ASP F OD2   1 
ATOM   19045 N N     . LEU F 1 341 ? -76.874  -9.067   -27.000 1.00 23.70  ? 341  LEU F N     1 
ATOM   19046 C CA    . LEU F 1 341 ? -76.841  -7.978   -26.039 1.00 22.30  ? 341  LEU F CA    1 
ATOM   19047 C C     . LEU F 1 341 ? -76.047  -6.820   -26.605 1.00 24.78  ? 341  LEU F C     1 
ATOM   19048 O O     . LEU F 1 341 ? -75.151  -7.009   -27.434 1.00 27.66  ? 341  LEU F O     1 
ATOM   19049 C CB    . LEU F 1 341 ? -76.219  -8.453   -24.734 1.00 20.87  ? 341  LEU F CB    1 
ATOM   19050 C CG    . LEU F 1 341 ? -77.087  -9.414   -23.925 1.00 25.00  ? 341  LEU F CG    1 
ATOM   19051 C CD1   . LEU F 1 341 ? -76.299  -9.825   -22.687 1.00 22.50  ? 341  LEU F CD1   1 
ATOM   19052 C CD2   . LEU F 1 341 ? -78.444  -8.806   -23.573 1.00 22.91  ? 341  LEU F CD2   1 
ATOM   19053 N N     . GLN F 1 342 ? -76.327  -5.630   -26.081 1.00 27.11  ? 342  GLN F N     1 
ATOM   19054 C CA    . GLN F 1 342 ? -75.564  -4.462   -26.510 1.00 31.26  ? 342  GLN F CA    1 
ATOM   19055 C C     . GLN F 1 342 ? -74.778  -3.862   -25.359 1.00 29.65  ? 342  GLN F C     1 
ATOM   19056 O O     . GLN F 1 342 ? -74.967  -4.248   -24.207 1.00 30.08  ? 342  GLN F O     1 
ATOM   19057 C CB    . GLN F 1 342 ? -76.535  -3.533   -27.220 1.00 30.94  ? 342  GLN F CB    1 
ATOM   19058 C CG    . GLN F 1 342 ? -76.963  -4.118   -28.559 1.00 38.38  ? 342  GLN F CG    1 
ATOM   19059 C CD    . GLN F 1 342 ? -77.838  -3.143   -29.292 1.00 45.60  ? 342  GLN F CD    1 
ATOM   19060 O OE1   . GLN F 1 342 ? -79.018  -3.007   -28.968 1.00 53.29  ? 342  GLN F OE1   1 
ATOM   19061 N NE2   . GLN F 1 342 ? -77.239  -2.398   -30.212 1.00 53.00  ? 342  GLN F NE2   1 
ATOM   19062 N N     . VAL F 1 343 ? -73.880  -2.935   -25.693 1.00 31.20  ? 343  VAL F N     1 
ATOM   19063 C CA    . VAL F 1 343 ? -73.078  -2.228   -24.699 1.00 31.28  ? 343  VAL F CA    1 
ATOM   19064 C C     . VAL F 1 343 ? -73.894  -1.093   -24.070 1.00 33.64  ? 343  VAL F C     1 
ATOM   19065 O O     . VAL F 1 343 ? -74.745  -0.474   -24.721 1.00 37.14  ? 343  VAL F O     1 
ATOM   19066 C CB    . VAL F 1 343 ? -71.790  -1.726   -25.370 1.00 31.09  ? 343  VAL F CB    1 
ATOM   19067 C CG1   . VAL F 1 343 ? -70.888  -1.029   -24.373 1.00 31.56  ? 343  VAL F CG1   1 
ATOM   19068 C CG2   . VAL F 1 343 ? -71.044  -2.866   -26.073 1.00 30.12  ? 343  VAL F CG2   1 
ATOM   19069 N N     . VAL F 1 344 ? -73.656  -0.859   -22.773 1.00 36.59  ? 344  VAL F N     1 
ATOM   19070 C CA    . VAL F 1 344 ? -74.331  0.189    -22.018 1.00 35.46  ? 344  VAL F CA    1 
ATOM   19071 C C     . VAL F 1 344 ? -73.459  1.443    -22.006 1.00 37.26  ? 344  VAL F C     1 
ATOM   19072 O O     . VAL F 1 344 ? -72.351  1.393    -21.486 1.00 34.79  ? 344  VAL F O     1 
ATOM   19073 C CB    . VAL F 1 344 ? -74.567  -0.315   -20.579 1.00 40.04  ? 344  VAL F CB    1 
ATOM   19074 C CG1   . VAL F 1 344 ? -75.080  0.784    -19.655 1.00 38.46  ? 344  VAL F CG1   1 
ATOM   19075 C CG2   . VAL F 1 344 ? -75.514  -1.504   -20.520 1.00 34.31  ? 344  VAL F CG2   1 
ATOM   19076 N N     . GLY F 1 345 ? -73.988  2.576    -22.517 1.00 45.53  ? 345  GLY F N     1 
ATOM   19077 C CA    . GLY F 1 345 ? -73.425  3.919    -22.349 1.00 48.43  ? 345  GLY F CA    1 
ATOM   19078 C C     . GLY F 1 345 ? -73.831  4.583    -21.018 1.00 52.30  ? 345  GLY F C     1 
ATOM   19079 O O     . GLY F 1 345 ? -73.911  3.948    -19.965 1.00 52.30  ? 345  GLY F O     1 
ATOM   19080 N N     . LYS F 1 346 ? -74.100  5.895    -21.050 1.00 56.31  ? 346  LYS F N     1 
ATOM   19081 C CA    . LYS F 1 346 ? -74.420  6.638    -19.836 1.00 66.19  ? 346  LYS F CA    1 
ATOM   19082 C C     . LYS F 1 346 ? -74.994  7.988    -20.242 1.00 68.74  ? 346  LYS F C     1 
ATOM   19083 O O     . LYS F 1 346 ? -74.412  8.651    -21.108 1.00 62.77  ? 346  LYS F O     1 
ATOM   19084 C CB    . LYS F 1 346 ? -73.207  6.919    -18.926 1.00 66.33  ? 346  LYS F CB    1 
ATOM   19085 C CG    . LYS F 1 346 ? -73.547  7.440    -17.560 1.00 75.09  ? 346  LYS F CG    1 
ATOM   19086 C CD    . LYS F 1 346 ? -72.328  7.902    -16.751 1.00 80.74  ? 346  LYS F CD    1 
ATOM   19087 C CE    . LYS F 1 346 ? -72.523  8.088    -15.272 1.00 76.26  ? 346  LYS F CE    1 
ATOM   19088 N NZ    . LYS F 1 346 ? -71.712  7.173    -14.442 1.00 70.15  ? 346  LYS F NZ    1 
ATOM   19089 N N     . ASP F 1 347 ? -76.132  8.353    -19.620 1.00 73.66  ? 347  ASP F N     1 
ATOM   19090 C CA    . ASP F 1 347 ? -76.814  9.632    -19.798 1.00 81.80  ? 347  ASP F CA    1 
ATOM   19091 C C     . ASP F 1 347 ? -77.118  9.875    -21.278 1.00 77.47  ? 347  ASP F C     1 
ATOM   19092 O O     . ASP F 1 347 ? -77.923  9.156    -21.855 1.00 70.54  ? 347  ASP F O     1 
ATOM   19093 C CB    . ASP F 1 347 ? -76.092  10.788   -19.106 1.00 83.50  ? 347  ASP F CB    1 
ATOM   19094 C CG    . ASP F 1 347 ? -75.798  10.625   -17.618 1.00 87.35  ? 347  ASP F CG    1 
ATOM   19095 O OD1   . ASP F 1 347 ? -76.698  10.173   -16.868 1.00 88.85  ? 347  ASP F OD1   1 
ATOM   19096 O OD2   . ASP F 1 347 ? -74.665  10.958   -17.209 1.00 90.56  ? 347  ASP F OD2   1 
ATOM   19097 N N     . ASN F 1 348 ? -76.451  10.877   -21.876 1.00 85.55  ? 348  ASN F N     1 
ATOM   19098 C CA    . ASN F 1 348 ? -76.688  11.303   -23.248 1.00 90.50  ? 348  ASN F CA    1 
ATOM   19099 C C     . ASN F 1 348 ? -76.100  10.314   -24.260 1.00 86.42  ? 348  ASN F C     1 
ATOM   19100 O O     . ASN F 1 348 ? -76.496  10.311   -25.431 1.00 77.29  ? 348  ASN F O     1 
ATOM   19101 C CB    . ASN F 1 348 ? -76.058  12.665   -23.530 1.00 107.82 ? 348  ASN F CB    1 
ATOM   19102 C CG    . ASN F 1 348 ? -76.586  13.786   -22.666 1.00 120.70 ? 348  ASN F CG    1 
ATOM   19103 O OD1   . ASN F 1 348 ? -76.329  13.793   -21.460 1.00 124.15 ? 348  ASN F OD1   1 
ATOM   19104 N ND2   . ASN F 1 348 ? -77.264  14.770   -23.250 1.00 118.58 ? 348  ASN F ND2   1 
ATOM   19105 N N     . VAL F 1 349 ? -75.134  9.493    -23.812 1.00 85.09  ? 349  VAL F N     1 
ATOM   19106 C CA    . VAL F 1 349 ? -74.439  8.540    -24.674 1.00 80.76  ? 349  VAL F CA    1 
ATOM   19107 C C     . VAL F 1 349 ? -75.178  7.198    -24.662 1.00 66.45  ? 349  VAL F C     1 
ATOM   19108 O O     . VAL F 1 349 ? -75.082  6.432    -23.697 1.00 58.48  ? 349  VAL F O     1 
ATOM   19109 C CB    . VAL F 1 349 ? -72.942  8.383    -24.330 1.00 80.56  ? 349  VAL F CB    1 
ATOM   19110 C CG1   . VAL F 1 349 ? -72.176  7.633    -25.430 1.00 77.65  ? 349  VAL F CG1   1 
ATOM   19111 C CG2   . VAL F 1 349 ? -72.305  9.733    -24.027 1.00 69.29  ? 349  VAL F CG2   1 
ATOM   19112 N N     . VAL F 1 350 ? -75.892  6.932    -25.768 1.00 56.41  ? 350  VAL F N     1 
ATOM   19113 C CA    . VAL F 1 350 ? -76.762  5.771    -25.906 1.00 63.18  ? 350  VAL F CA    1 
ATOM   19114 C C     . VAL F 1 350 ? -76.084  4.777    -26.852 1.00 55.22  ? 350  VAL F C     1 
ATOM   19115 O O     . VAL F 1 350 ? -75.884  5.097    -28.014 1.00 52.78  ? 350  VAL F O     1 
ATOM   19116 C CB    . VAL F 1 350 ? -78.166  6.196    -26.416 1.00 63.94  ? 350  VAL F CB    1 
ATOM   19117 C CG1   . VAL F 1 350 ? -79.093  5.016    -26.729 1.00 49.86  ? 350  VAL F CG1   1 
ATOM   19118 C CG2   . VAL F 1 350 ? -78.866  7.198    -25.499 1.00 65.81  ? 350  VAL F CG2   1 
ATOM   19119 N N     . LEU F 1 351 ? -75.737  3.580    -26.348 1.00 52.50  ? 351  LEU F N     1 
ATOM   19120 C CA    . LEU F 1 351 ? -75.059  2.555    -27.140 1.00 50.17  ? 351  LEU F CA    1 
ATOM   19121 C C     . LEU F 1 351 ? -75.983  1.377    -27.487 1.00 45.32  ? 351  LEU F C     1 
ATOM   19122 O O     . LEU F 1 351 ? -75.628  0.560    -28.334 1.00 46.30  ? 351  LEU F O     1 
ATOM   19123 C CB    . LEU F 1 351 ? -73.744  2.115    -26.484 1.00 56.81  ? 351  LEU F CB    1 
ATOM   19124 C CG    . LEU F 1 351 ? -72.735  3.235    -26.188 1.00 54.18  ? 351  LEU F CG    1 
ATOM   19125 C CD1   . LEU F 1 351 ? -71.619  2.671    -25.332 1.00 51.94  ? 351  LEU F CD1   1 
ATOM   19126 C CD2   . LEU F 1 351 ? -72.189  3.916    -27.446 1.00 48.10  ? 351  LEU F CD2   1 
ATOM   19127 N N     . GLY F 1 352 ? -77.170  1.292    -26.860 1.00 47.04  ? 352  GLY F N     1 
ATOM   19128 C CA    . GLY F 1 352 ? -78.172  0.287    -27.208 1.00 43.63  ? 352  GLY F CA    1 
ATOM   19129 C C     . GLY F 1 352 ? -78.598  -0.602   -26.031 1.00 46.68  ? 352  GLY F C     1 
ATOM   19130 O O     . GLY F 1 352 ? -79.711  -1.129   -26.039 1.00 46.19  ? 352  GLY F O     1 
ATOM   19131 N N     . GLY F 1 353 ? -77.729  -0.762   -25.014 1.00 43.87  ? 353  GLY F N     1 
ATOM   19132 C CA    . GLY F 1 353 ? -77.954  -1.774   -23.988 1.00 43.72  ? 353  GLY F CA    1 
ATOM   19133 C C     . GLY F 1 353 ? -78.637  -1.258   -22.721 1.00 48.12  ? 353  GLY F C     1 
ATOM   19134 O O     . GLY F 1 353 ? -78.839  -2.040   -21.787 1.00 40.94  ? 353  GLY F O     1 
ATOM   19135 N N     . GLU F 1 354 ? -79.022  0.033    -22.682 1.00 53.66  ? 354  GLU F N     1 
ATOM   19136 C CA    . GLU F 1 354 ? -79.338  0.672    -21.398 1.00 57.03  ? 354  GLU F CA    1 
ATOM   19137 C C     . GLU F 1 354 ? -80.763  0.414    -20.883 1.00 51.18  ? 354  GLU F C     1 
ATOM   19138 O O     . GLU F 1 354 ? -80.948  0.418    -19.663 1.00 56.18  ? 354  GLU F O     1 
ATOM   19139 C CB    . GLU F 1 354 ? -78.736  2.057    -21.119 1.00 62.85  ? 354  GLU F CB    1 
ATOM   19140 C CG    . GLU F 1 354 ? -78.746  3.020    -22.302 1.00 68.42  ? 354  GLU F CG    1 
ATOM   19141 C CD    . GLU F 1 354 ? -77.861  2.703    -23.501 1.00 67.01  ? 354  GLU F CD    1 
ATOM   19142 O OE1   . GLU F 1 354 ? -78.436  2.256    -24.526 1.00 61.78  ? 354  GLU F OE1   1 
ATOM   19143 O OE2   . GLU F 1 354 ? -76.629  2.933    -23.449 1.00 61.14  ? 354  GLU F OE2   1 
ATOM   19144 N N     . GLY F 1 355 ? -81.764  0.171    -21.746 1.00 40.39  ? 355  GLY F N     1 
ATOM   19145 C CA    . GLY F 1 355 ? -83.110  -0.076   -21.224 1.00 36.48  ? 355  GLY F CA    1 
ATOM   19146 C C     . GLY F 1 355 ? -83.213  -1.431   -20.512 1.00 34.60  ? 355  GLY F C     1 
ATOM   19147 O O     . GLY F 1 355 ? -82.408  -2.322   -20.754 1.00 35.23  ? 355  GLY F O     1 
ATOM   19148 N N     . VAL F 1 356 ? -84.201  -1.601   -19.629 1.00 32.21  ? 356  VAL F N     1 
ATOM   19149 C CA    . VAL F 1 356 ? -84.494  -2.922   -19.101 1.00 27.98  ? 356  VAL F CA    1 
ATOM   19150 C C     . VAL F 1 356 ? -84.785  -3.883   -20.264 1.00 28.92  ? 356  VAL F C     1 
ATOM   19151 O O     . VAL F 1 356 ? -85.486  -3.541   -21.222 1.00 25.39  ? 356  VAL F O     1 
ATOM   19152 C CB    . VAL F 1 356 ? -85.707  -2.747   -18.171 1.00 28.81  ? 356  VAL F CB    1 
ATOM   19153 C CG1   . VAL F 1 356 ? -86.208  -4.079   -17.632 1.00 21.93  ? 356  VAL F CG1   1 
ATOM   19154 C CG2   . VAL F 1 356 ? -85.372  -1.818   -17.009 1.00 31.84  ? 356  VAL F CG2   1 
ATOM   19155 N N     . ASN F 1 357 ? -84.262  -5.112   -20.157 1.00 25.90  ? 357  ASN F N     1 
ATOM   19156 C CA    . ASN F 1 357 ? -84.218  -6.043   -21.270 1.00 23.03  ? 357  ASN F CA    1 
ATOM   19157 C C     . ASN F 1 357 ? -84.750  -7.401   -20.800 1.00 23.63  ? 357  ASN F C     1 
ATOM   19158 O O     . ASN F 1 357 ? -83.984  -8.321   -20.482 1.00 23.48  ? 357  ASN F O     1 
ATOM   19159 C CB    . ASN F 1 357 ? -82.795  -6.109   -21.800 1.00 23.38  ? 357  ASN F CB    1 
ATOM   19160 C CG    . ASN F 1 357 ? -82.583  -7.107   -22.922 1.00 28.38  ? 357  ASN F CG    1 
ATOM   19161 O OD1   . ASN F 1 357 ? -83.519  -7.540   -23.615 1.00 25.51  ? 357  ASN F OD1   1 
ATOM   19162 N ND2   . ASN F 1 357 ? -81.333  -7.515   -23.082 1.00 29.24  ? 357  ASN F ND2   1 
ATOM   19163 N N     . PRO F 1 358 ? -86.078  -7.584   -20.708 1.00 21.12  ? 358  PRO F N     1 
ATOM   19164 C CA    . PRO F 1 358 ? -86.621  -8.851   -20.199 1.00 23.27  ? 358  PRO F CA    1 
ATOM   19165 C C     . PRO F 1 358 ? -86.424  -10.026  -21.160 1.00 23.58  ? 358  PRO F C     1 
ATOM   19166 O O     . PRO F 1 358 ? -86.917  -9.984   -22.274 1.00 24.93  ? 358  PRO F O     1 
ATOM   19167 C CB    . PRO F 1 358 ? -88.107  -8.564   -19.913 1.00 18.29  ? 358  PRO F CB    1 
ATOM   19168 C CG    . PRO F 1 358 ? -88.369  -7.327   -20.772 1.00 20.83  ? 358  PRO F CG    1 
ATOM   19169 C CD    . PRO F 1 358 ? -87.087  -6.594   -21.105 1.00 19.99  ? 358  PRO F CD    1 
ATOM   19170 N N     . ARG F 1 359 ? -85.703  -11.058  -20.721 1.00 24.82  ? 359  ARG F N     1 
ATOM   19171 C CA    . ARG F 1 359 ? -85.507  -12.277  -21.496 1.00 22.07  ? 359  ARG F CA    1 
ATOM   19172 C C     . ARG F 1 359 ? -86.134  -13.427  -20.717 1.00 25.70  ? 359  ARG F C     1 
ATOM   19173 O O     . ARG F 1 359 ? -85.819  -13.628  -19.533 1.00 28.57  ? 359  ARG F O     1 
ATOM   19174 C CB    . ARG F 1 359 ? -84.006  -12.540  -21.709 1.00 20.16  ? 359  ARG F CB    1 
ATOM   19175 C CG    . ARG F 1 359 ? -83.264  -11.448  -22.459 1.00 18.92  ? 359  ARG F CG    1 
ATOM   19176 C CD    . ARG F 1 359 ? -83.808  -11.292  -23.903 1.00 20.28  ? 359  ARG F CD    1 
ATOM   19177 N NE    . ARG F 1 359 ? -82.993  -10.331  -24.673 1.00 23.71  ? 359  ARG F NE    1 
ATOM   19178 C CZ    . ARG F 1 359 ? -81.869  -10.593  -25.334 1.00 22.27  ? 359  ARG F CZ    1 
ATOM   19179 N NH1   . ARG F 1 359 ? -81.142  -9.617   -25.896 1.00 20.92  ? 359  ARG F NH1   1 
ATOM   19180 N NH2   . ARG F 1 359 ? -81.486  -11.855  -25.440 1.00 20.70  ? 359  ARG F NH2   1 
ATOM   19181 N N     . SER F 1 360 ? -87.010  -14.185  -21.385 1.00 23.62  ? 360  SER F N     1 
ATOM   19182 C CA    . SER F 1 360 ? -87.794  -15.217  -20.730 1.00 22.15  ? 360  SER F CA    1 
ATOM   19183 C C     . SER F 1 360 ? -87.412  -16.623  -21.201 1.00 23.07  ? 360  SER F C     1 
ATOM   19184 O O     . SER F 1 360 ? -86.886  -16.812  -22.323 1.00 20.64  ? 360  SER F O     1 
ATOM   19185 C CB    . SER F 1 360 ? -89.262  -14.966  -20.908 1.00 21.42  ? 360  SER F CB    1 
ATOM   19186 O OG    . SER F 1 360 ? -89.620  -13.772  -20.241 1.00 22.84  ? 360  SER F OG    1 
ATOM   19187 N N     . PHE F 1 361 ? -87.727  -17.590  -20.320 1.00 20.42  ? 361  PHE F N     1 
ATOM   19188 C CA    . PHE F 1 361 ? -87.445  -19.003  -20.503 1.00 22.21  ? 361  PHE F CA    1 
ATOM   19189 C C     . PHE F 1 361 ? -88.628  -19.763  -19.922 1.00 23.16  ? 361  PHE F C     1 
ATOM   19190 O O     . PHE F 1 361 ? -89.282  -19.279  -18.995 1.00 23.54  ? 361  PHE F O     1 
ATOM   19191 C CB    . PHE F 1 361 ? -86.182  -19.327  -19.701 1.00 20.73  ? 361  PHE F CB    1 
ATOM   19192 C CG    . PHE F 1 361 ? -84.999  -18.505  -20.200 1.00 20.31  ? 361  PHE F CG    1 
ATOM   19193 C CD1   . PHE F 1 361 ? -84.199  -18.969  -21.257 1.00 18.89  ? 361  PHE F CD1   1 
ATOM   19194 C CD2   . PHE F 1 361 ? -84.730  -17.249  -19.655 1.00 18.63  ? 361  PHE F CD2   1 
ATOM   19195 C CE1   . PHE F 1 361 ? -83.130  -18.203  -21.720 1.00 18.75  ? 361  PHE F CE1   1 
ATOM   19196 C CE2   . PHE F 1 361 ? -83.662  -16.486  -20.126 1.00 20.08  ? 361  PHE F CE2   1 
ATOM   19197 C CZ    . PHE F 1 361 ? -82.873  -16.963  -21.173 1.00 18.17  ? 361  PHE F CZ    1 
ATOM   19198 N N     . VAL F 1 362 ? -88.916  -20.923  -20.513 1.00 23.31  ? 362  VAL F N     1 
ATOM   19199 C CA    . VAL F 1 362 ? -90.016  -21.780  -20.139 1.00 25.98  ? 362  VAL F CA    1 
ATOM   19200 C C     . VAL F 1 362 ? -89.417  -23.146  -19.816 1.00 28.07  ? 362  VAL F C     1 
ATOM   19201 O O     . VAL F 1 362 ? -88.727  -23.747  -20.656 1.00 25.59  ? 362  VAL F O     1 
ATOM   19202 C CB    . VAL F 1 362 ? -90.978  -21.940  -21.331 1.00 27.11  ? 362  VAL F CB    1 
ATOM   19203 C CG1   . VAL F 1 362 ? -92.096  -22.939  -20.973 1.00 21.89  ? 362  VAL F CG1   1 
ATOM   19204 C CG2   . VAL F 1 362 ? -91.518  -20.584  -21.784 1.00 24.78  ? 362  VAL F CG2   1 
ATOM   19205 N N     . GLY F 1 363 ? -89.742  -23.657  -18.618 1.00 29.12  ? 363  GLY F N     1 
ATOM   19206 C CA    . GLY F 1 363 ? -89.316  -24.993  -18.238 1.00 28.33  ? 363  GLY F CA    1 
ATOM   19207 C C     . GLY F 1 363 ? -88.541  -24.996  -16.916 1.00 31.18  ? 363  GLY F C     1 
ATOM   19208 O O     . GLY F 1 363 ? -88.089  -26.038  -16.485 1.00 35.35  ? 363  GLY F O     1 
ATOM   19209 N N     . ILE F 1 364 ? -88.420  -23.854  -16.245 1.00 30.54  ? 364  ILE F N     1 
ATOM   19210 C CA    . ILE F 1 364 ? -87.786  -23.821  -14.941 1.00 30.31  ? 364  ILE F CA    1 
ATOM   19211 C C     . ILE F 1 364 ? -88.876  -23.774  -13.881 1.00 31.10  ? 364  ILE F C     1 
ATOM   19212 O O     . ILE F 1 364 ? -89.613  -22.785  -13.779 1.00 33.33  ? 364  ILE F O     1 
ATOM   19213 C CB    . ILE F 1 364 ? -86.818  -22.628  -14.880 1.00 35.13  ? 364  ILE F CB    1 
ATOM   19214 C CG1   . ILE F 1 364 ? -85.612  -22.939  -15.748 1.00 35.27  ? 364  ILE F CG1   1 
ATOM   19215 C CG2   . ILE F 1 364 ? -86.427  -22.317  -13.433 1.00 32.89  ? 364  ILE F CG2   1 
ATOM   19216 C CD1   . ILE F 1 364 ? -84.630  -21.804  -15.860 1.00 39.16  ? 364  ILE F CD1   1 
ATOM   19217 N N     . GLY F 1 365 ? -88.974  -24.860  -13.094 1.00 35.30  ? 365  GLY F N     1 
ATOM   19218 C CA    . GLY F 1 365 ? -90.058  -25.056  -12.133 1.00 30.16  ? 365  GLY F CA    1 
ATOM   19219 C C     . GLY F 1 365 ? -89.658  -24.842  -10.667 1.00 32.40  ? 365  GLY F C     1 
ATOM   19220 O O     . GLY F 1 365 ? -90.513  -24.866  -9.792  1.00 38.92  ? 365  GLY F O     1 
ATOM   19221 N N     . GLN F 1 366 ? -88.373  -24.606  -10.380 1.00 33.65  ? 366  GLN F N     1 
ATOM   19222 C CA    . GLN F 1 366 ? -87.878  -24.538  -9.007  1.00 37.07  ? 366  GLN F CA    1 
ATOM   19223 C C     . GLN F 1 366 ? -87.638  -23.081  -8.617  1.00 35.54  ? 366  GLN F C     1 
ATOM   19224 O O     . GLN F 1 366 ? -87.165  -22.293  -9.429  1.00 37.30  ? 366  GLN F O     1 
ATOM   19225 C CB    . GLN F 1 366 ? -86.578  -25.341  -8.862  1.00 38.96  ? 366  GLN F CB    1 
ATOM   19226 C CG    . GLN F 1 366 ? -86.756  -26.852  -9.034  1.00 52.01  ? 366  GLN F CG    1 
ATOM   19227 C CD    . GLN F 1 366 ? -87.918  -27.429  -8.241  1.00 57.79  ? 366  GLN F CD    1 
ATOM   19228 O OE1   . GLN F 1 366 ? -88.011  -27.255  -7.018  1.00 61.17  ? 366  GLN F OE1   1 
ATOM   19229 N NE2   . GLN F 1 366 ? -88.838  -28.096  -8.932  1.00 53.50  ? 366  GLN F NE2   1 
ATOM   19230 N N     . PRO F 1 367 ? -87.933  -22.664  -7.366  1.00 37.17  ? 367  PRO F N     1 
ATOM   19231 C CA    . PRO F 1 367 ? -87.648  -21.284  -6.957  1.00 35.08  ? 367  PRO F CA    1 
ATOM   19232 C C     . PRO F 1 367 ? -86.156  -20.957  -6.982  1.00 35.44  ? 367  PRO F C     1 
ATOM   19233 O O     . PRO F 1 367 ? -85.337  -21.799  -6.611  1.00 30.00  ? 367  PRO F O     1 
ATOM   19234 C CB    . PRO F 1 367 ? -88.212  -21.120  -5.545  1.00 33.99  ? 367  PRO F CB    1 
ATOM   19235 C CG    . PRO F 1 367 ? -88.648  -22.529  -5.160  1.00 33.95  ? 367  PRO F CG    1 
ATOM   19236 C CD    . PRO F 1 367 ? -88.554  -23.499  -6.320  1.00 34.56  ? 367  PRO F CD    1 
ATOM   19237 N N     . ILE F 1 368 ? -85.821  -19.721  -7.382  1.00 29.82  ? 368  ILE F N     1 
ATOM   19238 C CA    . ILE F 1 368 ? -84.441  -19.353  -7.593  1.00 29.07  ? 368  ILE F CA    1 
ATOM   19239 C C     . ILE F 1 368 ? -84.036  -18.427  -6.456  1.00 30.91  ? 368  ILE F C     1 
ATOM   19240 O O     . ILE F 1 368 ? -84.789  -17.552  -6.070  1.00 33.04  ? 368  ILE F O     1 
ATOM   19241 C CB    . ILE F 1 368 ? -84.257  -18.699  -8.983  1.00 27.72  ? 368  ILE F CB    1 
ATOM   19242 C CG1   . ILE F 1 368 ? -84.279  -19.774  -10.092 1.00 30.73  ? 368  ILE F CG1   1 
ATOM   19243 C CG2   . ILE F 1 368 ? -82.987  -17.823  -9.059  1.00 23.60  ? 368  ILE F CG2   1 
ATOM   19244 C CD1   . ILE F 1 368 ? -84.531  -19.240  -11.500 1.00 29.14  ? 368  ILE F CD1   1 
ATOM   19245 N N     . GLN F 1 369 ? -82.802  -18.567  -5.988  1.00 35.32  ? 369  GLN F N     1 
ATOM   19246 C CA    . GLN F 1 369 ? -82.296  -17.659  -4.985  1.00 37.98  ? 369  GLN F CA    1 
ATOM   19247 C C     . GLN F 1 369 ? -81.593  -16.464  -5.617  1.00 35.34  ? 369  GLN F C     1 
ATOM   19248 O O     . GLN F 1 369 ? -81.805  -15.337  -5.185  1.00 34.74  ? 369  GLN F O     1 
ATOM   19249 C CB    . GLN F 1 369 ? -81.368  -18.392  -4.017  1.00 42.66  ? 369  GLN F CB    1 
ATOM   19250 C CG    . GLN F 1 369 ? -81.069  -17.546  -2.783  1.00 60.51  ? 369  GLN F CG    1 
ATOM   19251 C CD    . GLN F 1 369 ? -79.670  -17.774  -2.256  1.00 85.49  ? 369  GLN F CD    1 
ATOM   19252 O OE1   . GLN F 1 369 ? -79.323  -18.908  -1.913  1.00 87.41  ? 369  GLN F OE1   1 
ATOM   19253 N NE2   . GLN F 1 369 ? -78.848  -16.725  -2.282  1.00 97.32  ? 369  GLN F NE2   1 
ATOM   19254 N N     . ARG F 1 370 ? -80.721  -16.705  -6.601  1.00 34.68  ? 370  ARG F N     1 
ATOM   19255 C CA    . ARG F 1 370 ? -79.886  -15.625  -7.124  1.00 36.05  ? 370  ARG F CA    1 
ATOM   19256 C C     . ARG F 1 370 ? -79.468  -15.950  -8.564  1.00 31.10  ? 370  ARG F C     1 
ATOM   19257 O O     . ARG F 1 370 ? -79.267  -17.123  -8.914  1.00 28.73  ? 370  ARG F O     1 
ATOM   19258 C CB    . ARG F 1 370 ? -78.651  -15.594  -6.218  1.00 37.59  ? 370  ARG F CB    1 
ATOM   19259 C CG    . ARG F 1 370 ? -77.963  -14.253  -6.039  1.00 56.85  ? 370  ARG F CG    1 
ATOM   19260 C CD    . ARG F 1 370 ? -76.956  -14.328  -4.893  1.00 68.34  ? 370  ARG F CD    1 
ATOM   19261 N NE    . ARG F 1 370 ? -75.623  -14.579  -5.458  1.00 82.44  ? 370  ARG F NE    1 
ATOM   19262 C CZ    . ARG F 1 370 ? -74.612  -13.700  -5.562  1.00 94.70  ? 370  ARG F CZ    1 
ATOM   19263 N NH1   . ARG F 1 370 ? -74.691  -12.506  -4.976  1.00 72.69  ? 370  ARG F NH1   1 
ATOM   19264 N NH2   . ARG F 1 370 ? -73.520  -14.035  -6.251  1.00 93.01  ? 370  ARG F NH2   1 
ATOM   19265 N N     . ILE F 1 371 ? -79.297  -14.908  -9.384  1.00 23.80  ? 371  ILE F N     1 
ATOM   19266 C CA    . ILE F 1 371 ? -78.787  -15.060  -10.736 1.00 24.35  ? 371  ILE F CA    1 
ATOM   19267 C C     . ILE F 1 371 ? -77.703  -14.007  -10.937 1.00 26.11  ? 371  ILE F C     1 
ATOM   19268 O O     . ILE F 1 371 ? -77.946  -12.832  -10.633 1.00 28.52  ? 371  ILE F O     1 
ATOM   19269 C CB    . ILE F 1 371 ? -79.903  -14.881  -11.787 1.00 23.16  ? 371  ILE F CB    1 
ATOM   19270 C CG1   . ILE F 1 371 ? -81.148  -15.706  -11.461 1.00 22.93  ? 371  ILE F CG1   1 
ATOM   19271 C CG2   . ILE F 1 371 ? -79.350  -15.137  -13.199 1.00 22.35  ? 371  ILE F CG2   1 
ATOM   19272 C CD1   . ILE F 1 371 ? -82.247  -15.650  -12.525 1.00 23.76  ? 371  ILE F CD1   1 
ATOM   19273 N N     . HIS F 1 372 ? -76.551  -14.392  -11.523 1.00 27.20  ? 372  HIS F N     1 
ATOM   19274 C CA    . HIS F 1 372 ? -75.486  -13.416  -11.732 1.00 26.40  ? 372  HIS F CA    1 
ATOM   19275 C C     . HIS F 1 372 ? -74.696  -13.714  -13.008 1.00 27.27  ? 372  HIS F C     1 
ATOM   19276 O O     . HIS F 1 372 ? -74.504  -14.883  -13.368 1.00 24.21  ? 372  HIS F O     1 
ATOM   19277 C CB    . HIS F 1 372 ? -74.595  -13.322  -10.491 1.00 26.63  ? 372  HIS F CB    1 
ATOM   19278 C CG    . HIS F 1 372 ? -73.792  -14.544  -10.222 1.00 32.51  ? 372  HIS F CG    1 
ATOM   19279 N ND1   . HIS F 1 372 ? -74.254  -15.630  -9.483  1.00 36.39  ? 372  HIS F ND1   1 
ATOM   19280 C CD2   . HIS F 1 372 ? -72.518  -14.834  -10.626 1.00 35.17  ? 372  HIS F CD2   1 
ATOM   19281 C CE1   . HIS F 1 372 ? -73.296  -16.568  -9.460  1.00 36.03  ? 372  HIS F CE1   1 
ATOM   19282 N NE2   . HIS F 1 372 ? -72.237  -16.102  -10.147 1.00 35.98  ? 372  HIS F NE2   1 
ATOM   19283 N N     . TRP F 1 373 ? -74.222  -12.643  -13.674 1.00 23.77  ? 373  TRP F N     1 
ATOM   19284 C CA    . TRP F 1 373 ? -73.352  -12.769  -14.832 1.00 23.78  ? 373  TRP F CA    1 
ATOM   19285 C C     . TRP F 1 373 ? -72.009  -13.361  -14.404 1.00 27.21  ? 373  TRP F C     1 
ATOM   19286 O O     . TRP F 1 373 ? -71.398  -12.877  -13.449 1.00 27.83  ? 373  TRP F O     1 
ATOM   19287 C CB    . TRP F 1 373 ? -73.123  -11.392  -15.465 1.00 20.93  ? 373  TRP F CB    1 
ATOM   19288 C CG    . TRP F 1 373 ? -74.295  -10.765  -16.181 1.00 24.94  ? 373  TRP F CG    1 
ATOM   19289 C CD1   . TRP F 1 373 ? -74.745  -9.483   -16.003 1.00 27.60  ? 373  TRP F CD1   1 
ATOM   19290 C CD2   . TRP F 1 373 ? -75.102  -11.317  -17.249 1.00 24.77  ? 373  TRP F CD2   1 
ATOM   19291 N NE1   . TRP F 1 373 ? -75.793  -9.211   -16.841 1.00 26.99  ? 373  TRP F NE1   1 
ATOM   19292 C CE2   . TRP F 1 373 ? -76.033  -10.309  -17.626 1.00 28.45  ? 373  TRP F CE2   1 
ATOM   19293 C CE3   . TRP F 1 373 ? -75.156  -12.558  -17.905 1.00 25.25  ? 373  TRP F CE3   1 
ATOM   19294 C CZ2   . TRP F 1 373 ? -76.981  -10.503  -18.646 1.00 27.66  ? 373  TRP F CZ2   1 
ATOM   19295 C CZ3   . TRP F 1 373 ? -76.086  -12.743  -18.911 1.00 25.13  ? 373  TRP F CZ3   1 
ATOM   19296 C CH2   . TRP F 1 373 ? -76.986  -11.725  -19.293 1.00 23.58  ? 373  TRP F CH2   1 
ATOM   19297 N N     . LEU F 1 374 ? -71.512  -14.364  -15.153 1.00 29.15  ? 374  LEU F N     1 
ATOM   19298 C CA    . LEU F 1 374 ? -70.189  -14.932  -14.902 1.00 26.43  ? 374  LEU F CA    1 
ATOM   19299 C C     . LEU F 1 374 ? -69.086  -13.901  -15.156 1.00 28.49  ? 374  LEU F C     1 
ATOM   19300 O O     . LEU F 1 374 ? -68.063  -13.987  -14.515 1.00 32.10  ? 374  LEU F O     1 
ATOM   19301 C CB    . LEU F 1 374 ? -69.908  -16.160  -15.756 1.00 23.70  ? 374  LEU F CB    1 
ATOM   19302 C CG    . LEU F 1 374 ? -70.761  -17.387  -15.448 1.00 26.83  ? 374  LEU F CG    1 
ATOM   19303 C CD1   . LEU F 1 374 ? -70.299  -18.547  -16.312 1.00 23.86  ? 374  LEU F CD1   1 
ATOM   19304 C CD2   . LEU F 1 374 ? -70.692  -17.717  -13.975 1.00 24.13  ? 374  LEU F CD2   1 
ATOM   19305 N N     . ASP F 1 375 ? -69.235  -12.970  -16.109 1.00 25.88  ? 375  ASP F N     1 
ATOM   19306 C CA    . ASP F 1 375 ? -68.104  -12.110  -16.426 1.00 26.62  ? 375  ASP F CA    1 
ATOM   19307 C C     . ASP F 1 375 ? -67.808  -11.081  -15.311 1.00 29.98  ? 375  ASP F C     1 
ATOM   19308 O O     . ASP F 1 375 ? -66.670  -10.647  -15.188 1.00 28.88  ? 375  ASP F O     1 
ATOM   19309 C CB    . ASP F 1 375 ? -68.306  -11.358  -17.738 1.00 24.89  ? 375  ASP F CB    1 
ATOM   19310 C CG    . ASP F 1 375 ? -69.636  -10.618  -17.815 1.00 27.53  ? 375  ASP F CG    1 
ATOM   19311 O OD1   . ASP F 1 375 ? -70.672  -11.294  -18.015 1.00 26.86  ? 375  ASP F OD1   1 
ATOM   19312 O OD2   . ASP F 1 375 ? -69.632  -9.373   -17.612 1.00 26.84  ? 375  ASP F OD2   1 
ATOM   19313 N N     . ASN F 1 376 ? -68.806  -10.618  -14.540 1.00 27.41  ? 376  ASN F N     1 
ATOM   19314 C CA    . ASN F 1 376 ? -68.532  -9.520   -13.621 1.00 28.99  ? 376  ASN F CA    1 
ATOM   19315 C C     . ASN F 1 376 ? -69.298  -9.677   -12.308 1.00 28.52  ? 376  ASN F C     1 
ATOM   19316 O O     . ASN F 1 376 ? -69.293  -8.769   -11.496 1.00 31.22  ? 376  ASN F O     1 
ATOM   19317 C CB    . ASN F 1 376 ? -68.804  -8.146   -14.238 1.00 25.90  ? 376  ASN F CB    1 
ATOM   19318 C CG    . ASN F 1 376 ? -70.285  -7.894   -14.454 1.00 29.63  ? 376  ASN F CG    1 
ATOM   19319 O OD1   . ASN F 1 376 ? -71.116  -8.795   -14.281 1.00 28.46  ? 376  ASN F OD1   1 
ATOM   19320 N ND2   . ASN F 1 376 ? -70.646  -6.686   -14.876 1.00 27.31  ? 376  ASN F ND2   1 
ATOM   19321 N N     . ASP F 1 377 ? -70.016  -10.787  -12.127 1.00 32.29  ? 377  ASP F N     1 
ATOM   19322 C CA    . ASP F 1 377 ? -70.739  -11.056  -10.885 1.00 35.52  ? 377  ASP F CA    1 
ATOM   19323 C C     . ASP F 1 377 ? -71.930  -10.138  -10.634 1.00 32.73  ? 377  ASP F C     1 
ATOM   19324 O O     . ASP F 1 377 ? -72.467  -10.172  -9.548  1.00 35.83  ? 377  ASP F O     1 
ATOM   19325 C CB    . ASP F 1 377 ? -69.819  -11.151  -9.670  1.00 39.30  ? 377  ASP F CB    1 
ATOM   19326 C CG    . ASP F 1 377 ? -68.872  -12.349  -9.706  1.00 47.74  ? 377  ASP F CG    1 
ATOM   19327 O OD1   . ASP F 1 377 ? -69.350  -13.475  -10.029 1.00 49.68  ? 377  ASP F OD1   1 
ATOM   19328 O OD2   . ASP F 1 377 ? -67.669  -12.158  -9.422  1.00 54.47  ? 377  ASP F OD2   1 
ATOM   19329 N N     . GLU F 1 378 ? -72.364  -9.331   -11.603 1.00 34.07  ? 378  GLU F N     1 
ATOM   19330 C CA    . GLU F 1 378 ? -73.545  -8.516   -11.367 1.00 30.89  ? 378  GLU F CA    1 
ATOM   19331 C C     . GLU F 1 378 ? -74.752  -9.409   -11.114 1.00 33.55  ? 378  GLU F C     1 
ATOM   19332 O O     . GLU F 1 378 ? -74.957  -10.394  -11.830 1.00 40.94  ? 378  GLU F O     1 
ATOM   19333 C CB    . GLU F 1 378 ? -73.738  -7.560   -12.535 1.00 32.84  ? 378  GLU F CB    1 
ATOM   19334 C CG    . GLU F 1 378 ? -74.963  -6.672   -12.367 1.00 37.90  ? 378  GLU F CG    1 
ATOM   19335 C CD    . GLU F 1 378 ? -75.391  -5.968   -13.640 1.00 40.66  ? 378  GLU F CD    1 
ATOM   19336 O OE1   . GLU F 1 378 ? -74.796  -6.227   -14.718 1.00 42.02  ? 378  GLU F OE1   1 
ATOM   19337 O OE2   . GLU F 1 378 ? -76.367  -5.183   -13.545 1.00 45.71  ? 378  GLU F OE2   1 
ATOM   19338 N N     . VAL F 1 379 ? -75.539  -9.077   -10.084 1.00 30.10  ? 379  VAL F N     1 
ATOM   19339 C CA    . VAL F 1 379 ? -76.751  -9.812   -9.740  1.00 28.56  ? 379  VAL F CA    1 
ATOM   19340 C C     . VAL F 1 379 ? -77.894  -9.292   -10.606 1.00 29.94  ? 379  VAL F C     1 
ATOM   19341 O O     . VAL F 1 379 ? -78.050  -8.083   -10.753 1.00 30.46  ? 379  VAL F O     1 
ATOM   19342 C CB    . VAL F 1 379 ? -77.047  -9.574   -8.244  1.00 31.22  ? 379  VAL F CB    1 
ATOM   19343 C CG1   . VAL F 1 379 ? -78.440  -10.064  -7.850  1.00 28.08  ? 379  VAL F CG1   1 
ATOM   19344 C CG2   . VAL F 1 379 ? -75.995  -10.254  -7.379  1.00 28.04  ? 379  VAL F CG2   1 
ATOM   19345 N N     . LEU F 1 380 ? -78.697  -10.205  -11.171 1.00 28.01  ? 380  LEU F N     1 
ATOM   19346 C CA    . LEU F 1 380 ? -79.753  -9.816   -12.098 1.00 27.75  ? 380  LEU F CA    1 
ATOM   19347 C C     . LEU F 1 380 ? -81.091  -9.829   -11.368 1.00 28.82  ? 380  LEU F C     1 
ATOM   19348 O O     . LEU F 1 380 ? -81.340  -10.703  -10.540 1.00 27.38  ? 380  LEU F O     1 
ATOM   19349 C CB    . LEU F 1 380 ? -79.800  -10.779  -13.290 1.00 28.45  ? 380  LEU F CB    1 
ATOM   19350 C CG    . LEU F 1 380 ? -78.507  -10.971  -14.090 1.00 26.76  ? 380  LEU F CG    1 
ATOM   19351 C CD1   . LEU F 1 380 ? -78.827  -11.647  -15.398 1.00 29.83  ? 380  LEU F CD1   1 
ATOM   19352 C CD2   . LEU F 1 380 ? -77.959  -9.594   -14.324 1.00 29.30  ? 380  LEU F CD2   1 
ATOM   19353 N N     . SER F 1 381 ? -81.996  -8.916   -11.729 1.00 26.51  ? 381  SER F N     1 
ATOM   19354 C CA    . SER F 1 381 ? -83.340  -9.083   -11.187 1.00 29.12  ? 381  SER F CA    1 
ATOM   19355 C C     . SER F 1 381 ? -84.137  -10.069  -12.045 1.00 30.99  ? 381  SER F C     1 
ATOM   19356 O O     . SER F 1 381 ? -83.848  -10.236  -13.239 1.00 28.29  ? 381  SER F O     1 
ATOM   19357 C CB    . SER F 1 381 ? -84.022  -7.764   -11.037 1.00 33.76  ? 381  SER F CB    1 
ATOM   19358 O OG    . SER F 1 381 ? -84.044  -7.089   -12.277 1.00 39.87  ? 381  SER F OG    1 
ATOM   19359 N N     . PHE F 1 382 ? -85.121  -10.750  -11.434 1.00 28.08  ? 382  PHE F N     1 
ATOM   19360 C CA    . PHE F 1 382 ? -85.888  -11.759  -12.148 1.00 27.31  ? 382  PHE F CA    1 
ATOM   19361 C C     . PHE F 1 382 ? -87.263  -11.909  -11.497 1.00 31.08  ? 382  PHE F C     1 
ATOM   19362 O O     . PHE F 1 382 ? -87.461  -11.476  -10.361 1.00 33.18  ? 382  PHE F O     1 
ATOM   19363 C CB    . PHE F 1 382 ? -85.094  -13.072  -12.119 1.00 29.33  ? 382  PHE F CB    1 
ATOM   19364 C CG    . PHE F 1 382 ? -84.993  -13.714  -10.736 1.00 26.23  ? 382  PHE F CG    1 
ATOM   19365 C CD1   . PHE F 1 382 ? -85.992  -14.600  -10.296 1.00 26.27  ? 382  PHE F CD1   1 
ATOM   19366 C CD2   . PHE F 1 382 ? -83.952  -13.390  -9.867  1.00 24.53  ? 382  PHE F CD2   1 
ATOM   19367 C CE1   . PHE F 1 382 ? -85.945  -15.164  -9.021  1.00 26.56  ? 382  PHE F CE1   1 
ATOM   19368 C CE2   . PHE F 1 382 ? -83.900  -13.966  -8.593  1.00 27.45  ? 382  PHE F CE2   1 
ATOM   19369 C CZ    . PHE F 1 382 ? -84.898  -14.851  -8.167  1.00 26.79  ? 382  PHE F CZ    1 
ATOM   19370 N N     . THR F 1 383 ? -88.218  -12.499  -12.235 1.00 27.88  ? 383  THR F N     1 
ATOM   19371 C CA    . THR F 1 383 ? -89.517  -12.895  -11.719 1.00 28.63  ? 383  THR F CA    1 
ATOM   19372 C C     . THR F 1 383 ? -89.737  -14.341  -12.174 1.00 32.25  ? 383  THR F C     1 
ATOM   19373 O O     . THR F 1 383 ? -89.215  -14.763  -13.217 1.00 30.16  ? 383  THR F O     1 
ATOM   19374 C CB    . THR F 1 383 ? -90.637  -11.992  -12.231 1.00 31.91  ? 383  THR F CB    1 
ATOM   19375 O OG1   . THR F 1 383 ? -90.651  -12.122  -13.653 1.00 37.74  ? 383  THR F OG1   1 
ATOM   19376 C CG2   . THR F 1 383 ? -90.476  -10.523  -11.874 1.00 30.52  ? 383  THR F CG2   1 
ATOM   19377 N N     . GLN F 1 384 ? -90.550  -15.081  -11.412 1.00 33.06  ? 384  GLN F N     1 
ATOM   19378 C CA    . GLN F 1 384 ? -90.923  -16.432  -11.796 1.00 33.36  ? 384  GLN F CA    1 
ATOM   19379 C C     . GLN F 1 384 ? -92.433  -16.587  -11.755 1.00 32.33  ? 384  GLN F C     1 
ATOM   19380 O O     . GLN F 1 384 ? -93.083  -15.964  -10.942 1.00 30.45  ? 384  GLN F O     1 
ATOM   19381 C CB    . GLN F 1 384 ? -90.326  -17.489  -10.870 1.00 29.24  ? 384  GLN F CB    1 
ATOM   19382 C CG    . GLN F 1 384 ? -88.809  -17.488  -10.905 1.00 29.48  ? 384  GLN F CG    1 
ATOM   19383 C CD    . GLN F 1 384 ? -88.195  -18.620  -10.116 1.00 29.98  ? 384  GLN F CD    1 
ATOM   19384 O OE1   . GLN F 1 384 ? -87.811  -18.450  -8.957  1.00 31.98  ? 384  GLN F OE1   1 
ATOM   19385 N NE2   . GLN F 1 384 ? -88.079  -19.781  -10.739 1.00 25.32  ? 384  GLN F NE2   1 
ATOM   19386 N N     . ASP F 1 385 ? -92.964  -17.425  -12.651 1.00 35.61  ? 385  ASP F N     1 
ATOM   19387 C CA    . ASP F 1 385 ? -94.260  -18.054  -12.462 1.00 31.73  ? 385  ASP F CA    1 
ATOM   19388 C C     . ASP F 1 385 ? -94.027  -19.561  -12.387 1.00 30.23  ? 385  ASP F C     1 
ATOM   19389 O O     . ASP F 1 385 ? -93.814  -20.208  -13.422 1.00 30.31  ? 385  ASP F O     1 
ATOM   19390 C CB    . ASP F 1 385 ? -95.222  -17.670  -13.581 1.00 32.96  ? 385  ASP F CB    1 
ATOM   19391 C CG    . ASP F 1 385 ? -96.563  -18.396  -13.576 1.00 37.10  ? 385  ASP F CG    1 
ATOM   19392 O OD1   . ASP F 1 385 ? -96.672  -19.427  -12.881 1.00 41.54  ? 385  ASP F OD1   1 
ATOM   19393 O OD2   . ASP F 1 385 ? -97.484  -17.943  -14.285 1.00 41.06  ? 385  ASP F OD2   1 
ATOM   19394 N N     . LEU F 1 386 ? -94.040  -20.105  -11.170 1.00 32.25  ? 386  LEU F N     1 
ATOM   19395 C CA    . LEU F 1 386 ? -93.655  -21.497  -10.967 1.00 31.63  ? 386  LEU F CA    1 
ATOM   19396 C C     . LEU F 1 386 ? -94.689  -22.450  -11.561 1.00 31.66  ? 386  LEU F C     1 
ATOM   19397 O O     . LEU F 1 386 ? -94.318  -23.509  -12.044 1.00 37.10  ? 386  LEU F O     1 
ATOM   19398 C CB    . LEU F 1 386 ? -93.349  -21.819  -9.509  1.00 35.56  ? 386  LEU F CB    1 
ATOM   19399 C CG    . LEU F 1 386 ? -92.262  -20.963  -8.864  1.00 39.11  ? 386  LEU F CG    1 
ATOM   19400 C CD1   . LEU F 1 386 ? -92.267  -21.163  -7.345  1.00 38.02  ? 386  LEU F CD1   1 
ATOM   19401 C CD2   . LEU F 1 386 ? -90.935  -21.348  -9.442  1.00 36.36  ? 386  LEU F CD2   1 
ATOM   19402 N N     . ASP F 1 387 ? -95.967  -22.076  -11.595 1.00 34.41  ? 387  ASP F N     1 
ATOM   19403 C CA    . ASP F 1 387 ? -96.971  -22.957  -12.182 1.00 42.05  ? 387  ASP F CA    1 
ATOM   19404 C C     . ASP F 1 387 ? -96.743  -23.167  -13.678 1.00 41.03  ? 387  ASP F C     1 
ATOM   19405 O O     . ASP F 1 387 ? -96.903  -24.274  -14.172 1.00 38.15  ? 387  ASP F O     1 
ATOM   19406 C CB    . ASP F 1 387 ? -98.393  -22.524  -11.868 1.00 48.64  ? 387  ASP F CB    1 
ATOM   19407 C CG    . ASP F 1 387 ? -98.671  -22.461  -10.371 1.00 61.51  ? 387  ASP F CG    1 
ATOM   19408 O OD1   . ASP F 1 387 ? -98.435  -23.500  -9.698  1.00 65.60  ? 387  ASP F OD1   1 
ATOM   19409 O OD2   . ASP F 1 387 ? -99.074  -21.375  -9.881  1.00 58.25  ? 387  ASP F OD2   1 
ATOM   19410 N N     . LYS F 1 388 ? -96.391  -22.097  -14.396 1.00 36.26  ? 388  LYS F N     1 
ATOM   19411 C CA    . LYS F 1 388 ? -96.239  -22.185  -15.838 1.00 34.42  ? 388  LYS F CA    1 
ATOM   19412 C C     . LYS F 1 388 ? -94.766  -22.410  -16.194 1.00 33.58  ? 388  LYS F C     1 
ATOM   19413 O O     . LYS F 1 388 ? -94.437  -22.620  -17.355 1.00 31.42  ? 388  LYS F O     1 
ATOM   19414 C CB    . LYS F 1 388 ? -96.941  -20.987  -16.488 1.00 31.40  ? 388  LYS F CB    1 
ATOM   19415 C CG    . LYS F 1 388 ? -98.432  -21.285  -16.604 1.00 31.67  ? 388  LYS F CG    1 
ATOM   19416 C CD    . LYS F 1 388 ? -99.224  -20.194  -17.280 1.00 25.98  ? 388  LYS F CD    1 
ATOM   19417 C CE    . LYS F 1 388 ? -100.563 -20.682  -17.646 1.00 24.64  ? 388  LYS F CE    1 
ATOM   19418 N NZ    . LYS F 1 388 ? -101.291 -19.538  -18.203 1.00 26.25  ? 388  LYS F NZ    1 
ATOM   19419 N N     . LYS F 1 389 ? -93.896  -22.367  -15.181 1.00 30.29  ? 389  LYS F N     1 
ATOM   19420 C CA    . LYS F 1 389 ? -92.474  -22.639  -15.338 1.00 29.91  ? 389  LYS F CA    1 
ATOM   19421 C C     . LYS F 1 389 ? -91.808  -21.546  -16.170 1.00 29.89  ? 389  LYS F C     1 
ATOM   19422 O O     . LYS F 1 389 ? -90.950  -21.827  -17.012 1.00 33.96  ? 389  LYS F O     1 
ATOM   19423 C CB    . LYS F 1 389 ? -92.205  -24.064  -15.837 1.00 34.58  ? 389  LYS F CB    1 
ATOM   19424 C CG    . LYS F 1 389 ? -92.816  -25.175  -14.986 1.00 42.22  ? 389  LYS F CG    1 
ATOM   19425 C CD    . LYS F 1 389 ? -92.882  -26.470  -15.772 1.00 59.06  ? 389  LYS F CD    1 
ATOM   19426 C CE    . LYS F 1 389 ? -93.544  -27.583  -15.053 1.00 68.28  ? 389  LYS F CE    1 
ATOM   19427 N NZ    . LYS F 1 389 ? -92.498  -28.255  -14.280 1.00 78.80  ? 389  LYS F NZ    1 
ATOM   19428 N N     . VAL F 1 390 ? -92.161  -20.293  -15.865 1.00 28.66  ? 390  VAL F N     1 
ATOM   19429 C CA    . VAL F 1 390 ? -91.624  -19.142  -16.574 1.00 23.33  ? 390  VAL F CA    1 
ATOM   19430 C C     . VAL F 1 390 ? -90.601  -18.446  -15.688 1.00 22.90  ? 390  VAL F C     1 
ATOM   19431 O O     . VAL F 1 390 ? -90.866  -18.177  -14.514 1.00 26.59  ? 390  VAL F O     1 
ATOM   19432 C CB    . VAL F 1 390 ? -92.731  -18.149  -16.995 1.00 21.41  ? 390  VAL F CB    1 
ATOM   19433 C CG1   . VAL F 1 390 ? -92.153  -16.914  -17.671 1.00 17.00  ? 390  VAL F CG1   1 
ATOM   19434 C CG2   . VAL F 1 390 ? -93.773  -18.800  -17.901 1.00 21.17  ? 390  VAL F CG2   1 
ATOM   19435 N N     . LEU F 1 391 ? -89.450  -18.134  -16.291 1.00 21.20  ? 391  LEU F N     1 
ATOM   19436 C CA    . LEU F 1 391 ? -88.449  -17.264  -15.717 1.00 22.65  ? 391  LEU F CA    1 
ATOM   19437 C C     . LEU F 1 391 ? -88.238  -16.070  -16.646 1.00 26.79  ? 391  LEU F C     1 
ATOM   19438 O O     . LEU F 1 391 ? -88.064  -16.250  -17.851 1.00 26.84  ? 391  LEU F O     1 
ATOM   19439 C CB    . LEU F 1 391 ? -87.161  -18.080  -15.540 1.00 19.41  ? 391  LEU F CB    1 
ATOM   19440 C CG    . LEU F 1 391 ? -85.931  -17.266  -15.157 1.00 19.33  ? 391  LEU F CG    1 
ATOM   19441 C CD1   . LEU F 1 391 ? -86.113  -16.606  -13.796 1.00 19.75  ? 391  LEU F CD1   1 
ATOM   19442 C CD2   . LEU F 1 391 ? -84.659  -18.061  -15.189 1.00 19.34  ? 391  LEU F CD2   1 
ATOM   19443 N N     . THR F 1 392 ? -88.227  -14.854  -16.077 1.00 27.11  ? 392  THR F N     1 
ATOM   19444 C CA    . THR F 1 392 ? -87.906  -13.650  -16.833 1.00 23.98  ? 392  THR F CA    1 
ATOM   19445 C C     . THR F 1 392 ? -86.795  -12.920  -16.094 1.00 25.08  ? 392  THR F C     1 
ATOM   19446 O O     . THR F 1 392 ? -86.972  -12.636  -14.918 1.00 26.00  ? 392  THR F O     1 
ATOM   19447 C CB    . THR F 1 392 ? -89.133  -12.740  -16.953 1.00 25.22  ? 392  THR F CB    1 
ATOM   19448 O OG1   . THR F 1 392 ? -90.182  -13.476  -17.572 1.00 22.42  ? 392  THR F OG1   1 
ATOM   19449 C CG2   . THR F 1 392 ? -88.857  -11.520  -17.808 1.00 25.59  ? 392  THR F CG2   1 
ATOM   19450 N N     . VAL F 1 393 ? -85.677  -12.618  -16.776 1.00 23.76  ? 393  VAL F N     1 
ATOM   19451 C CA    . VAL F 1 393 ? -84.574  -11.894  -16.165 1.00 24.40  ? 393  VAL F CA    1 
ATOM   19452 C C     . VAL F 1 393 ? -84.441  -10.561  -16.904 1.00 26.71  ? 393  VAL F C     1 
ATOM   19453 O O     . VAL F 1 393 ? -84.775  -10.471  -18.091 1.00 27.35  ? 393  VAL F O     1 
ATOM   19454 C CB    . VAL F 1 393 ? -83.216  -12.629  -16.158 1.00 23.57  ? 393  VAL F CB    1 
ATOM   19455 C CG1   . VAL F 1 393 ? -83.272  -14.027  -15.574 1.00 23.68  ? 393  VAL F CG1   1 
ATOM   19456 C CG2   . VAL F 1 393 ? -82.606  -12.698  -17.548 1.00 25.30  ? 393  VAL F CG2   1 
ATOM   19457 N N     . ASP F 1 394 ? -83.939  -9.544   -16.205 1.00 30.09  ? 394  ASP F N     1 
ATOM   19458 C CA    . ASP F 1 394 ? -83.503  -8.328   -16.864 1.00 27.77  ? 394  ASP F CA    1 
ATOM   19459 C C     . ASP F 1 394 ? -82.044  -8.525   -17.254 1.00 28.30  ? 394  ASP F C     1 
ATOM   19460 O O     . ASP F 1 394 ? -81.152  -8.407   -16.405 1.00 25.36  ? 394  ASP F O     1 
ATOM   19461 C CB    . ASP F 1 394 ? -83.670  -7.090   -16.000 1.00 29.01  ? 394  ASP F CB    1 
ATOM   19462 C CG    . ASP F 1 394 ? -83.042  -5.819   -16.561 1.00 33.50  ? 394  ASP F CG    1 
ATOM   19463 O OD1   . ASP F 1 394 ? -82.755  -5.774   -17.807 1.00 31.97  ? 394  ASP F OD1   1 
ATOM   19464 O OD2   . ASP F 1 394 ? -82.827  -4.882   -15.747 1.00 35.93  ? 394  ASP F OD2   1 
ATOM   19465 N N     . ALA F 1 395 ? -81.814  -8.830   -18.545 1.00 27.01  ? 395  ALA F N     1 
ATOM   19466 C CA    . ALA F 1 395 ? -80.469  -9.133   -19.007 1.00 26.20  ? 395  ALA F CA    1 
ATOM   19467 C C     . ALA F 1 395 ? -79.743  -7.828   -19.320 1.00 27.15  ? 395  ALA F C     1 
ATOM   19468 O O     . ALA F 1 395 ? -79.856  -7.326   -20.437 1.00 25.91  ? 395  ALA F O     1 
ATOM   19469 C CB    . ALA F 1 395 ? -80.510  -10.077  -20.188 1.00 25.50  ? 395  ALA F CB    1 
ATOM   19470 N N     . THR F 1 396 ? -79.018  -7.279   -18.328 1.00 23.16  ? 396  THR F N     1 
ATOM   19471 C CA    . THR F 1 396 ? -78.358  -5.998   -18.524 1.00 22.99  ? 396  THR F CA    1 
ATOM   19472 C C     . THR F 1 396 ? -77.310  -6.103   -19.624 1.00 23.38  ? 396  THR F C     1 
ATOM   19473 O O     . THR F 1 396 ? -76.737  -7.178   -19.838 1.00 21.92  ? 396  THR F O     1 
ATOM   19474 C CB    . THR F 1 396 ? -77.810  -5.473   -17.192 1.00 23.27  ? 396  THR F CB    1 
ATOM   19475 O OG1   . THR F 1 396 ? -76.991  -6.520   -16.668 1.00 23.69  ? 396  THR F OG1   1 
ATOM   19476 C CG2   . THR F 1 396 ? -78.930  -5.132   -16.214 1.00 17.75  ? 396  THR F CG2   1 
ATOM   19477 N N     . GLY F 1 397 ? -77.052  -4.970   -20.302 1.00 23.90  ? 397  GLY F N     1 
ATOM   19478 C CA    . GLY F 1 397 ? -76.085  -4.913   -21.384 1.00 24.60  ? 397  GLY F CA    1 
ATOM   19479 C C     . GLY F 1 397 ? -74.648  -4.954   -20.864 1.00 26.90  ? 397  GLY F C     1 
ATOM   19480 O O     . GLY F 1 397 ? -74.414  -4.937   -19.663 1.00 29.46  ? 397  GLY F O     1 
ATOM   19481 N N     . TYR F 1 398 ? -73.680  -5.017   -21.775 1.00 25.94  ? 398  TYR F N     1 
ATOM   19482 C CA    . TYR F 1 398 ? -72.283  -5.105   -21.376 1.00 26.16  ? 398  TYR F CA    1 
ATOM   19483 C C     . TYR F 1 398 ? -71.822  -3.799   -20.749 1.00 26.92  ? 398  TYR F C     1 
ATOM   19484 O O     . TYR F 1 398 ? -72.153  -2.714   -21.237 1.00 28.99  ? 398  TYR F O     1 
ATOM   19485 C CB    . TYR F 1 398 ? -71.387  -5.407   -22.586 1.00 25.79  ? 398  TYR F CB    1 
ATOM   19486 C CG    . TYR F 1 398 ? -71.759  -6.715   -23.269 1.00 27.85  ? 398  TYR F CG    1 
ATOM   19487 C CD1   . TYR F 1 398 ? -71.576  -7.930   -22.592 1.00 26.79  ? 398  TYR F CD1   1 
ATOM   19488 C CD2   . TYR F 1 398 ? -72.303  -6.737   -24.562 1.00 24.57  ? 398  TYR F CD2   1 
ATOM   19489 C CE1   . TYR F 1 398 ? -71.932  -9.129   -23.177 1.00 26.12  ? 398  TYR F CE1   1 
ATOM   19490 C CE2   . TYR F 1 398 ? -72.651  -7.942   -25.166 1.00 26.73  ? 398  TYR F CE2   1 
ATOM   19491 C CZ    . TYR F 1 398 ? -72.445  -9.130   -24.466 1.00 30.64  ? 398  TYR F CZ    1 
ATOM   19492 O OH    . TYR F 1 398 ? -72.779  -10.356  -24.957 1.00 33.63  ? 398  TYR F OH    1 
ATOM   19493 N N     . PRO F 1 399 ? -70.969  -3.853   -19.698 1.00 27.31  ? 399  PRO F N     1 
ATOM   19494 C CA    . PRO F 1 399 ? -70.220  -2.661   -19.303 1.00 23.10  ? 399  PRO F CA    1 
ATOM   19495 C C     . PRO F 1 399 ? -69.428  -2.115   -20.491 1.00 23.33  ? 399  PRO F C     1 
ATOM   19496 O O     . PRO F 1 399 ? -68.828  -2.871   -21.269 1.00 24.82  ? 399  PRO F O     1 
ATOM   19497 C CB    . PRO F 1 399 ? -69.219  -3.168   -18.257 1.00 25.66  ? 399  PRO F CB    1 
ATOM   19498 C CG    . PRO F 1 399 ? -69.682  -4.559   -17.878 1.00 25.75  ? 399  PRO F CG    1 
ATOM   19499 C CD    . PRO F 1 399 ? -70.605  -5.074   -18.958 1.00 25.45  ? 399  PRO F CD    1 
ATOM   19500 N N     . TYR F 1 400 ? -69.441  -0.793   -20.649 1.00 23.55  ? 400  TYR F N     1 
ATOM   19501 C CA    . TYR F 1 400 ? -68.668  -0.157   -21.687 1.00 22.58  ? 400  TYR F CA    1 
ATOM   19502 C C     . TYR F 1 400 ? -67.239  -0.705   -21.636 1.00 25.29  ? 400  TYR F C     1 
ATOM   19503 O O     . TYR F 1 400 ? -66.681  -0.902   -20.555 1.00 24.35  ? 400  TYR F O     1 
ATOM   19504 C CB    . TYR F 1 400 ? -68.734  1.357    -21.535 1.00 20.79  ? 400  TYR F CB    1 
ATOM   19505 C CG    . TYR F 1 400 ? -67.857  2.061    -22.568 1.00 23.01  ? 400  TYR F CG    1 
ATOM   19506 C CD1   . TYR F 1 400 ? -68.280  2.215    -23.901 1.00 20.81  ? 400  TYR F CD1   1 
ATOM   19507 C CD2   . TYR F 1 400 ? -66.587  2.515    -22.222 1.00 19.54  ? 400  TYR F CD2   1 
ATOM   19508 C CE1   . TYR F 1 400 ? -67.487  2.860    -24.836 1.00 20.38  ? 400  TYR F CE1   1 
ATOM   19509 C CE2   . TYR F 1 400 ? -65.780  3.147    -23.159 1.00 22.07  ? 400  TYR F CE2   1 
ATOM   19510 C CZ    . TYR F 1 400 ? -66.233  3.328    -24.462 1.00 23.06  ? 400  TYR F CZ    1 
ATOM   19511 O OH    . TYR F 1 400 ? -65.401  3.933    -25.369 1.00 25.11  ? 400  TYR F OH    1 
ATOM   19512 N N     . GLY F 1 401 ? -66.668  -0.979   -22.812 1.00 23.86  ? 401  GLY F N     1 
ATOM   19513 C CA    . GLY F 1 401 ? -65.314  -1.500   -22.858 1.00 25.55  ? 401  GLY F CA    1 
ATOM   19514 C C     . GLY F 1 401 ? -65.281  -3.021   -22.959 1.00 28.15  ? 401  GLY F C     1 
ATOM   19515 O O     . GLY F 1 401 ? -64.214  -3.618   -23.132 1.00 27.67  ? 401  GLY F O     1 
ATOM   19516 N N     . SER F 1 402 ? -66.447  -3.671   -22.910 1.00 29.83  ? 402  SER F N     1 
ATOM   19517 C CA    . SER F 1 402 ? -66.404  -5.117   -23.068 1.00 28.28  ? 402  SER F CA    1 
ATOM   19518 C C     . SER F 1 402 ? -67.605  -5.602   -23.898 1.00 29.54  ? 402  SER F C     1 
ATOM   19519 O O     . SER F 1 402 ? -68.556  -4.850   -24.118 1.00 28.19  ? 402  SER F O     1 
ATOM   19520 C CB    . SER F 1 402 ? -66.254  -5.779   -21.733 1.00 26.93  ? 402  SER F CB    1 
ATOM   19521 O OG    . SER F 1 402 ? -67.525  -5.735   -21.107 1.00 40.44  ? 402  SER F OG    1 
ATOM   19522 N N     . ASP F 1 403 ? -67.508  -6.822   -24.442 1.00 24.59  ? 403  ASP F N     1 
ATOM   19523 C CA    . ASP F 1 403 ? -68.562  -7.428   -25.236 1.00 21.98  ? 403  ASP F CA    1 
ATOM   19524 C C     . ASP F 1 403 ? -68.236  -8.917   -25.409 1.00 23.77  ? 403  ASP F C     1 
ATOM   19525 O O     . ASP F 1 403 ? -67.297  -9.254   -26.136 1.00 24.71  ? 403  ASP F O     1 
ATOM   19526 C CB    . ASP F 1 403 ? -68.726  -6.705   -26.567 1.00 23.62  ? 403  ASP F CB    1 
ATOM   19527 C CG    . ASP F 1 403 ? -69.894  -7.177   -27.434 1.00 32.30  ? 403  ASP F CG    1 
ATOM   19528 O OD1   . ASP F 1 403 ? -70.323  -8.364   -27.266 1.00 32.80  ? 403  ASP F OD1   1 
ATOM   19529 O OD2   . ASP F 1 403 ? -70.403  -6.351   -28.249 1.00 31.39  ? 403  ASP F OD2   1 
ATOM   19530 N N     . TRP F 1 404 ? -69.010  -9.782   -24.747 1.00 21.83  ? 404  TRP F N     1 
ATOM   19531 C CA    . TRP F 1 404 ? -68.687  -11.196  -24.626 1.00 25.20  ? 404  TRP F CA    1 
ATOM   19532 C C     . TRP F 1 404 ? -69.341  -12.037  -25.733 1.00 22.72  ? 404  TRP F C     1 
ATOM   19533 O O     . TRP F 1 404 ? -69.102  -13.237  -25.810 1.00 23.92  ? 404  TRP F O     1 
ATOM   19534 C CB    . TRP F 1 404 ? -69.054  -11.729  -23.224 1.00 20.43  ? 404  TRP F CB    1 
ATOM   19535 C CG    . TRP F 1 404 ? -68.187  -11.131  -22.155 1.00 23.80  ? 404  TRP F CG    1 
ATOM   19536 C CD1   . TRP F 1 404 ? -68.477  -10.021  -21.414 1.00 24.10  ? 404  TRP F CD1   1 
ATOM   19537 C CD2   . TRP F 1 404 ? -66.862  -11.549  -21.747 1.00 22.44  ? 404  TRP F CD2   1 
ATOM   19538 N NE1   . TRP F 1 404 ? -67.436  -9.720   -20.575 1.00 22.36  ? 404  TRP F NE1   1 
ATOM   19539 C CE2   . TRP F 1 404 ? -66.435  -10.636  -20.749 1.00 23.30  ? 404  TRP F CE2   1 
ATOM   19540 C CE3   . TRP F 1 404 ? -66.008  -12.596  -22.110 1.00 23.67  ? 404  TRP F CE3   1 
ATOM   19541 C CZ2   . TRP F 1 404 ? -65.196  -10.748  -20.110 1.00 23.86  ? 404  TRP F CZ2   1 
ATOM   19542 C CZ3   . TRP F 1 404 ? -64.776  -12.699  -21.487 1.00 24.51  ? 404  TRP F CZ3   1 
ATOM   19543 C CH2   . TRP F 1 404 ? -64.382  -11.792  -20.495 1.00 26.42  ? 404  TRP F CH2   1 
ATOM   19544 N N     . VAL F 1 405 ? -70.210  -11.422  -26.537 1.00 19.95  ? 405  VAL F N     1 
ATOM   19545 C CA    . VAL F 1 405 ? -70.894  -12.095  -27.634 1.00 21.00  ? 405  VAL F CA    1 
ATOM   19546 C C     . VAL F 1 405 ? -71.967  -13.067  -27.132 1.00 23.17  ? 405  VAL F C     1 
ATOM   19547 O O     . VAL F 1 405 ? -73.142  -12.946  -27.508 1.00 22.66  ? 405  VAL F O     1 
ATOM   19548 C CB    . VAL F 1 405 ? -69.975  -12.777  -28.667 1.00 20.46  ? 405  VAL F CB    1 
ATOM   19549 C CG1   . VAL F 1 405 ? -70.803  -13.399  -29.803 1.00 18.06  ? 405  VAL F CG1   1 
ATOM   19550 C CG2   . VAL F 1 405 ? -68.896  -11.803  -29.180 1.00 19.30  ? 405  VAL F CG2   1 
ATOM   19551 N N     . VAL F 1 406 ? -71.562  -14.090  -26.364 1.00 20.87  ? 406  VAL F N     1 
ATOM   19552 C CA    . VAL F 1 406 ? -72.526  -14.932  -25.665 1.00 19.26  ? 406  VAL F CA    1 
ATOM   19553 C C     . VAL F 1 406 ? -72.276  -14.697  -24.174 1.00 23.94  ? 406  VAL F C     1 
ATOM   19554 O O     . VAL F 1 406 ? -71.189  -15.026  -23.669 1.00 23.21  ? 406  VAL F O     1 
ATOM   19555 C CB    . VAL F 1 406 ? -72.360  -16.427  -25.998 1.00 19.03  ? 406  VAL F CB    1 
ATOM   19556 C CG1   . VAL F 1 406 ? -73.263  -17.320  -25.144 1.00 16.18  ? 406  VAL F CG1   1 
ATOM   19557 C CG2   . VAL F 1 406 ? -72.570  -16.725  -27.482 1.00 17.47  ? 406  VAL F CG2   1 
ATOM   19558 N N     . ARG F 1 407 ? -73.250  -14.087  -23.481 1.00 22.38  ? 407  ARG F N     1 
ATOM   19559 C CA    . ARG F 1 407 ? -73.070  -13.775  -22.065 1.00 23.87  ? 407  ARG F CA    1 
ATOM   19560 C C     . ARG F 1 407 ? -73.748  -14.858  -21.237 1.00 23.22  ? 407  ARG F C     1 
ATOM   19561 O O     . ARG F 1 407 ? -74.794  -15.370  -21.647 1.00 29.42  ? 407  ARG F O     1 
ATOM   19562 C CB    . ARG F 1 407 ? -73.645  -12.383  -21.760 1.00 24.71  ? 407  ARG F CB    1 
ATOM   19563 C CG    . ARG F 1 407 ? -72.959  -11.704  -20.589 1.00 26.94  ? 407  ARG F CG    1 
ATOM   19564 C CD    . ARG F 1 407 ? -73.610  -10.382  -20.218 1.00 25.65  ? 407  ARG F CD    1 
ATOM   19565 N NE    . ARG F 1 407 ? -72.760  -9.771   -19.198 1.00 25.27  ? 407  ARG F NE    1 
ATOM   19566 C CZ    . ARG F 1 407 ? -72.957  -8.542   -18.685 1.00 27.61  ? 407  ARG F CZ    1 
ATOM   19567 N NH1   . ARG F 1 407 ? -74.019  -7.795   -19.017 1.00 23.99  ? 407  ARG F NH1   1 
ATOM   19568 N NH2   . ARG F 1 407 ? -72.086  -8.086   -17.808 1.00 26.40  ? 407  ARG F NH2   1 
ATOM   19569 N N     . ILE F 1 408 ? -73.160  -15.229  -20.094 1.00 23.43  ? 408  ILE F N     1 
ATOM   19570 C CA    . ILE F 1 408 ? -73.673  -16.381  -19.357 1.00 24.26  ? 408  ILE F CA    1 
ATOM   19571 C C     . ILE F 1 408 ? -74.026  -15.968  -17.926 1.00 25.53  ? 408  ILE F C     1 
ATOM   19572 O O     . ILE F 1 408 ? -73.190  -15.408  -17.201 1.00 26.73  ? 408  ILE F O     1 
ATOM   19573 C CB    . ILE F 1 408 ? -72.655  -17.536  -19.371 1.00 23.12  ? 408  ILE F CB    1 
ATOM   19574 C CG1   . ILE F 1 408 ? -72.300  -17.965  -20.814 1.00 21.16  ? 408  ILE F CG1   1 
ATOM   19575 C CG2   . ILE F 1 408 ? -73.183  -18.710  -18.544 1.00 22.29  ? 408  ILE F CG2   1 
ATOM   19576 C CD1   . ILE F 1 408 ? -71.169  -18.991  -20.877 1.00 23.05  ? 408  ILE F CD1   1 
ATOM   19577 N N     . ALA F 1 409 ? -75.270  -16.255  -17.530 1.00 25.38  ? 409  ALA F N     1 
ATOM   19578 C CA    . ALA F 1 409 ? -75.747  -15.992  -16.177 1.00 27.14  ? 409  ALA F CA    1 
ATOM   19579 C C     . ALA F 1 409 ? -75.909  -17.319  -15.441 1.00 24.43  ? 409  ALA F C     1 
ATOM   19580 O O     . ALA F 1 409 ? -76.560  -18.236  -15.965 1.00 27.27  ? 409  ALA F O     1 
ATOM   19581 C CB    . ALA F 1 409 ? -77.068  -15.235  -16.211 1.00 22.40  ? 409  ALA F CB    1 
ATOM   19582 N N     . GLN F 1 410 ? -75.321  -17.410  -14.239 1.00 24.04  ? 410  GLN F N     1 
ATOM   19583 C CA    . GLN F 1 410 ? -75.480  -18.600  -13.404 1.00 26.92  ? 410  GLN F CA    1 
ATOM   19584 C C     . GLN F 1 410 ? -76.685  -18.456  -12.475 1.00 27.58  ? 410  GLN F C     1 
ATOM   19585 O O     . GLN F 1 410 ? -76.855  -17.423  -11.818 1.00 29.22  ? 410  GLN F O     1 
ATOM   19586 C CB    . GLN F 1 410 ? -74.260  -18.761  -12.517 1.00 27.11  ? 410  GLN F CB    1 
ATOM   19587 C CG    . GLN F 1 410 ? -74.293  -20.040  -11.689 1.00 33.42  ? 410  GLN F CG    1 
ATOM   19588 C CD    . GLN F 1 410 ? -73.010  -20.214  -10.901 1.00 35.03  ? 410  GLN F CD    1 
ATOM   19589 O OE1   . GLN F 1 410 ? -71.910  -20.269  -11.470 1.00 37.12  ? 410  GLN F OE1   1 
ATOM   19590 N NE2   . GLN F 1 410 ? -73.137  -20.228  -9.582  1.00 31.69  ? 410  GLN F NE2   1 
ATOM   19591 N N     . ILE F 1 411 ? -77.527  -19.493  -12.461 1.00 26.80  ? 411  ILE F N     1 
ATOM   19592 C CA    . ILE F 1 411 ? -78.675  -19.584  -11.575 1.00 26.76  ? 411  ILE F CA    1 
ATOM   19593 C C     . ILE F 1 411 ? -78.290  -20.404  -10.338 1.00 27.19  ? 411  ILE F C     1 
ATOM   19594 O O     . ILE F 1 411 ? -77.841  -21.541  -10.460 1.00 28.61  ? 411  ILE F O     1 
ATOM   19595 C CB    . ILE F 1 411 ? -79.857  -20.238  -12.301 1.00 24.43  ? 411  ILE F CB    1 
ATOM   19596 C CG1   . ILE F 1 411 ? -80.362  -19.388  -13.467 1.00 23.62  ? 411  ILE F CG1   1 
ATOM   19597 C CG2   . ILE F 1 411 ? -80.964  -20.573  -11.291 1.00 27.57  ? 411  ILE F CG2   1 
ATOM   19598 C CD1   . ILE F 1 411 ? -81.439  -20.050  -14.333 1.00 20.18  ? 411  ILE F CD1   1 
ATOM   19599 N N     . ASP F 1 412 ? -78.508  -19.831  -9.150  1.00 30.02  ? 412  ASP F N     1 
ATOM   19600 C CA    . ASP F 1 412 ? -78.391  -20.511  -7.859  1.00 31.75  ? 412  ASP F CA    1 
ATOM   19601 C C     . ASP F 1 412 ? -79.799  -20.759  -7.330  1.00 31.69  ? 412  ASP F C     1 
ATOM   19602 O O     . ASP F 1 412 ? -80.545  -19.817  -7.089  1.00 34.99  ? 412  ASP F O     1 
ATOM   19603 C CB    . ASP F 1 412 ? -77.593  -19.688  -6.857  1.00 32.67  ? 412  ASP F CB    1 
ATOM   19604 C CG    . ASP F 1 412 ? -76.170  -19.366  -7.294  1.00 39.12  ? 412  ASP F CG    1 
ATOM   19605 O OD1   . ASP F 1 412 ? -75.672  -20.080  -8.200  1.00 42.57  ? 412  ASP F OD1   1 
ATOM   19606 O OD2   . ASP F 1 412 ? -75.580  -18.370  -6.790  1.00 41.18  ? 412  ASP F OD2   1 
ATOM   19607 N N     . TYR F 1 413 ? -80.162  -22.034  -7.191  1.00 32.01  ? 413  TYR F N     1 
ATOM   19608 C CA    . TYR F 1 413 ? -81.458  -22.422  -6.671  1.00 33.43  ? 413  TYR F CA    1 
ATOM   19609 C C     . TYR F 1 413 ? -81.490  -22.334  -5.146  1.00 40.38  ? 413  TYR F C     1 
ATOM   19610 O O     . TYR F 1 413 ? -80.459  -22.453  -4.471  1.00 37.55  ? 413  TYR F O     1 
ATOM   19611 C CB    . TYR F 1 413 ? -81.769  -23.862  -7.084  1.00 30.74  ? 413  TYR F CB    1 
ATOM   19612 C CG    . TYR F 1 413 ? -82.124  -23.876  -8.555  1.00 32.56  ? 413  TYR F CG    1 
ATOM   19613 C CD1   . TYR F 1 413 ? -83.348  -23.354  -8.997  1.00 31.54  ? 413  TYR F CD1   1 
ATOM   19614 C CD2   . TYR F 1 413 ? -81.222  -24.367  -9.499  1.00 32.25  ? 413  TYR F CD2   1 
ATOM   19615 C CE1   . TYR F 1 413 ? -83.665  -23.329  -10.347 1.00 34.27  ? 413  TYR F CE1   1 
ATOM   19616 C CE2   . TYR F 1 413 ? -81.545  -24.364  -10.847 1.00 33.59  ? 413  TYR F CE2   1 
ATOM   19617 C CZ    . TYR F 1 413 ? -82.753  -23.822  -11.274 1.00 35.46  ? 413  TYR F CZ    1 
ATOM   19618 O OH    . TYR F 1 413 ? -83.079  -23.828  -12.599 1.00 29.75  ? 413  TYR F OH    1 
ATOM   19619 N N     . GLU F 1 414 ? -82.707  -22.106  -4.634  1.00 51.15  ? 414  GLU F N     1 
ATOM   19620 C CA    . GLU F 1 414 ? -83.008  -22.213  -3.214  1.00 63.05  ? 414  GLU F CA    1 
ATOM   19621 C C     . GLU F 1 414 ? -82.852  -23.670  -2.752  1.00 66.64  ? 414  GLU F C     1 
ATOM   19622 O O     . GLU F 1 414 ? -83.412  -24.557  -3.443  1.00 64.55  ? 414  GLU F O     1 
ATOM   19623 C CB    . GLU F 1 414 ? -84.391  -21.671  -2.854  1.00 62.95  ? 414  GLU F CB    1 
ATOM   19624 C CG    . GLU F 1 414 ? -84.388  -20.149  -2.887  1.00 74.71  ? 414  GLU F CG    1 
ATOM   19625 C CD    . GLU F 1 414 ? -85.441  -19.391  -2.138  1.00 92.09  ? 414  GLU F CD    1 
ATOM   19626 O OE1   . GLU F 1 414 ? -86.625  -19.806  -2.210  1.00 94.46  ? 414  GLU F OE1   1 
ATOM   19627 O OE2   . GLU F 1 414 ? -85.029  -18.370  -1.532  1.00 94.17  ? 414  GLU F OE2   1 
ATOM   19628 O OXT   . GLU F 1 414 ? -82.170  -23.850  -1.726  1.00 64.16  ? 414  GLU F OXT   1 
HETATM 19629 C C1    . JFZ G 2 .   ? -43.995  -47.992  9.785   1.00 64.68  ? 1001 JFZ A C1    1 
HETATM 19630 C C2    . JFZ G 2 .   ? -43.042  -46.828  10.012  1.00 57.08  ? 1001 JFZ A C2    1 
HETATM 19631 O O2    . JFZ G 2 .   ? -42.566  -46.830  11.350  1.00 32.54  ? 1001 JFZ A O2    1 
HETATM 19632 C C3    . JFZ G 2 .   ? -41.926  -46.898  8.986   1.00 47.54  ? 1001 JFZ A C3    1 
HETATM 19633 O O3    . JFZ G 2 .   ? -41.018  -45.807  9.135   1.00 33.57  ? 1001 JFZ A O3    1 
HETATM 19634 C C4    . JFZ G 2 .   ? -42.543  -46.820  7.616   1.00 46.20  ? 1001 JFZ A C4    1 
HETATM 19635 O O4    . JFZ G 2 .   ? -43.270  -45.606  7.550   1.00 33.64  ? 1001 JFZ A O4    1 
HETATM 19636 C C5    . JFZ G 2 .   ? -43.510  -47.978  7.432   1.00 42.73  ? 1001 JFZ A C5    1 
HETATM 19637 C C6    . JFZ G 2 .   ? -44.261  -47.878  6.131   1.00 35.66  ? 1001 JFZ A C6    1 
HETATM 19638 O O5    . JFZ G 2 .   ? -44.511  -47.933  8.473   1.00 54.96  ? 1001 JFZ A O5    1 
HETATM 19639 O O1    . JFZ G 2 .   ? -43.247  -49.186  9.903   1.00 92.44  ? 1001 JFZ A O1    1 
HETATM 19640 C "C1'" . JFZ G 2 .   ? -43.046  -49.719  11.164  1.00 104.08 ? 1001 JFZ A "C1'" 1 
HETATM 19641 C "C2'" . JFZ G 2 .   ? -42.270  -50.860  11.281  1.00 98.04  ? 1001 JFZ A "C2'" 1 
HETATM 19642 C "C3'" . JFZ G 2 .   ? -42.053  -51.422  12.521  1.00 114.41 ? 1001 JFZ A "C3'" 1 
HETATM 19643 C "C4'" . JFZ G 2 .   ? -42.631  -50.822  13.636  1.00 136.91 ? 1001 JFZ A "C4'" 1 
HETATM 19644 C "C5'" . JFZ G 2 .   ? -43.418  -49.679  13.528  1.00 122.69 ? 1001 JFZ A "C5'" 1 
HETATM 19645 C "C6'" . JFZ G 2 .   ? -43.623  -49.133  12.279  1.00 103.23 ? 1001 JFZ A "C6'" 1 
HETATM 19646 N "N1'" . JFZ G 2 .   ? -42.409  -51.408  14.951  1.00 140.48 ? 1001 JFZ A "N1'" 1 
HETATM 19647 O "O2'" . JFZ G 2 .   ? -42.923  -50.869  15.919  1.00 138.37 ? 1001 JFZ A "O2'" 1 
HETATM 19648 O "O3'" . JFZ G 2 .   ? -41.718  -52.412  15.028  1.00 140.11 ? 1001 JFZ A "O3'" 1 
HETATM 19649 C C1    . JFZ H 2 .   ? -18.368  -60.862  -26.204 1.00 61.57  ? 1001 JFZ B C1    1 
HETATM 19650 C C2    . JFZ H 2 .   ? -19.220  -60.130  -27.219 1.00 52.46  ? 1001 JFZ B C2    1 
HETATM 19651 O O2    . JFZ H 2 .   ? -19.785  -61.059  -28.139 1.00 36.53  ? 1001 JFZ B O2    1 
HETATM 19652 C C3    . JFZ H 2 .   ? -20.297  -59.381  -26.479 1.00 46.80  ? 1001 JFZ B C3    1 
HETATM 19653 O O3    . JFZ H 2 .   ? -21.070  -58.663  -27.433 1.00 38.74  ? 1001 JFZ B O3    1 
HETATM 19654 C C4    . JFZ H 2 .   ? -19.683  -58.440  -25.454 1.00 42.88  ? 1001 JFZ B C4    1 
HETATM 19655 O O4    . JFZ H 2 .   ? -18.907  -57.440  -26.109 1.00 29.65  ? 1001 JFZ B O4    1 
HETATM 19656 C C5    . JFZ H 2 .   ? -18.799  -59.235  -24.499 1.00 40.27  ? 1001 JFZ B C5    1 
HETATM 19657 C C6    . JFZ H 2 .   ? -18.035  -58.366  -23.530 1.00 32.98  ? 1001 JFZ B C6    1 
HETATM 19658 O O5    . JFZ H 2 .   ? -17.818  -59.975  -25.260 1.00 47.47  ? 1001 JFZ B O5    1 
HETATM 19659 O O1    . JFZ H 2 .   ? -19.211  -61.765  -25.515 1.00 74.45  ? 1001 JFZ B O1    1 
HETATM 19660 C "C1'" . JFZ H 2 .   ? -19.440  -63.011  -26.073 1.00 89.45  ? 1001 JFZ B "C1'" 1 
HETATM 19661 C "C2'" . JFZ H 2 .   ? -18.787  -63.395  -27.232 1.00 98.80  ? 1001 JFZ B "C2'" 1 
HETATM 19662 C "C3'" . JFZ H 2 .   ? -19.021  -64.641  -27.775 1.00 129.41 ? 1001 JFZ B "C3'" 1 
HETATM 19663 C "C4'" . JFZ H 2 .   ? -19.914  -65.492  -27.130 1.00 146.50 ? 1001 JFZ B "C4'" 1 
HETATM 19664 C "C5'" . JFZ H 2 .   ? -20.571  -65.118  -25.962 1.00 118.76 ? 1001 JFZ B "C5'" 1 
HETATM 19665 C "C6'" . JFZ H 2 .   ? -20.323  -63.867  -25.435 1.00 89.75  ? 1001 JFZ B "C6'" 1 
HETATM 19666 N "N1'" . JFZ H 2 .   ? -20.168  -66.811  -27.695 1.00 156.77 ? 1001 JFZ B "N1'" 1 
HETATM 19667 O "O2'" . JFZ H 2 .   ? -20.955  -67.545  -27.117 1.00 161.27 ? 1001 JFZ B "O2'" 1 
HETATM 19668 O "O3'" . JFZ H 2 .   ? -19.583  -67.124  -28.720 1.00 149.62 ? 1001 JFZ B "O3'" 1 
HETATM 19669 C C1    . JFZ I 2 .   ? -10.297  -95.755  -3.743  1.00 46.88  ? 1001 JFZ C C1    1 
HETATM 19670 C C2    . JFZ I 2 .   ? -9.775   -96.049  -2.342  1.00 42.26  ? 1001 JFZ C C2    1 
HETATM 19671 O O2    . JFZ I 2 .   ? -9.087   -94.909  -1.835  1.00 34.86  ? 1001 JFZ C O2    1 
HETATM 19672 C C3    . JFZ I 2 .   ? -10.909  -96.468  -1.395  1.00 34.61  ? 1001 JFZ C C3    1 
HETATM 19673 O O3    . JFZ I 2 .   ? -10.331  -97.060  -0.227  1.00 31.11  ? 1001 JFZ C O3    1 
HETATM 19674 C C4    . JFZ I 2 .   ? -11.899  -97.445  -2.031  1.00 35.42  ? 1001 JFZ C C4    1 
HETATM 19675 O O4    . JFZ I 2 .   ? -11.310  -98.726  -2.209  1.00 32.51  ? 1001 JFZ C O4    1 
HETATM 19676 C C5    . JFZ I 2 .   ? -12.339  -96.927  -3.389  1.00 33.36  ? 1001 JFZ C C5    1 
HETATM 19677 C C6    . JFZ I 2 .   ? -13.254  -97.877  -4.125  1.00 32.10  ? 1001 JFZ C C6    1 
HETATM 19678 O O5    . JFZ I 2 .   ? -11.154  -96.780  -4.195  1.00 39.19  ? 1001 JFZ C O5    1 
HETATM 19679 O O1    . JFZ I 2 .   ? -11.073  -94.575  -3.720  1.00 56.60  ? 1001 JFZ C O1    1 
HETATM 19680 C "C1'" . JFZ I 2 .   ? -10.482  -93.406  -4.163  1.00 81.49  ? 1001 JFZ C "C1'" 1 
HETATM 19681 C "C2'" . JFZ I 2 .   ? -11.212  -92.229  -4.154  1.00 90.26  ? 1001 JFZ C "C2'" 1 
HETATM 19682 C "C3'" . JFZ I 2 .   ? -10.631  -91.058  -4.595  1.00 90.64  ? 1001 JFZ C "C3'" 1 
HETATM 19683 C "C4'" . JFZ I 2 .   ? -9.313   -91.093  -5.043  1.00 113.02 ? 1001 JFZ C "C4'" 1 
HETATM 19684 C "C5'" . JFZ I 2 .   ? -8.574   -92.273  -5.055  1.00 94.46  ? 1001 JFZ C "C5'" 1 
HETATM 19685 C "C6'" . JFZ I 2 .   ? -9.171   -93.433  -4.610  1.00 82.62  ? 1001 JFZ C "C6'" 1 
HETATM 19686 N "N1'" . JFZ I 2 .   ? -8.691   -89.862  -5.511  1.00 131.18 ? 1001 JFZ C "N1'" 1 
HETATM 19687 O "O2'" . JFZ I 2 .   ? -9.354   -88.836  -5.493  1.00 126.86 ? 1001 JFZ C "O2'" 1 
HETATM 19688 O "O3'" . JFZ I 2 .   ? -7.535   -89.910  -5.900  1.00 123.28 ? 1001 JFZ C "O3'" 1 
HETATM 19689 C C1    . JFZ J 2 .   ? -51.587  -89.264  14.311  1.00 52.88  ? 1001 JFZ D C1    1 
HETATM 19690 C C2    . JFZ J 2 .   ? -52.239  -90.426  13.577  1.00 45.78  ? 1001 JFZ D C2    1 
HETATM 19691 O O2    . JFZ J 2 .   ? -53.180  -89.933  12.627  1.00 34.52  ? 1001 JFZ D O2    1 
HETATM 19692 C C3    . JFZ J 2 .   ? -51.167  -91.282  12.895  1.00 38.41  ? 1001 JFZ D C3    1 
HETATM 19693 O O3    . JFZ J 2 .   ? -51.766  -92.462  12.363  1.00 29.71  ? 1001 JFZ D O3    1 
HETATM 19694 C C4    . JFZ J 2 .   ? -50.037  -91.650  13.852  1.00 39.60  ? 1001 JFZ D C4    1 
HETATM 19695 O O4    . JFZ J 2 .   ? -50.516  -92.534  14.860  1.00 28.01  ? 1001 JFZ D O4    1 
HETATM 19696 C C5    . JFZ J 2 .   ? -49.502  -90.378  14.492  1.00 32.19  ? 1001 JFZ D C5    1 
HETATM 19697 C C6    . JFZ J 2 .   ? -48.422  -90.585  15.519  1.00 32.51  ? 1001 JFZ D C6    1 
HETATM 19698 O O5    . JFZ J 2 .   ? -50.588  -89.734  15.183  1.00 43.80  ? 1001 JFZ D O5    1 
HETATM 19699 O O1    . JFZ J 2 .   ? -50.915  -88.482  13.348  1.00 66.80  ? 1001 JFZ D O1    1 
HETATM 19700 C "C1'" . JFZ J 2 .   ? -51.514  -87.307  12.950  1.00 86.52  ? 1001 JFZ D "C1'" 1 
HETATM 19701 C "C2'" . JFZ J 2 .   ? -50.871  -86.507  12.022  1.00 96.67  ? 1001 JFZ D "C2'" 1 
HETATM 19702 C "C3'" . JFZ J 2 .   ? -51.452  -85.321  11.634  1.00 110.03 ? 1001 JFZ D "C3'" 1 
HETATM 19703 C "C4'" . JFZ J 2 .   ? -52.669  -84.965  12.205  1.00 116.64 ? 1001 JFZ D "C4'" 1 
HETATM 19704 C "C5'" . JFZ J 2 .   ? -53.317  -85.762  13.143  1.00 95.18  ? 1001 JFZ D "C5'" 1 
HETATM 19705 C "C6'" . JFZ J 2 .   ? -52.721  -86.944  13.518  1.00 84.25  ? 1001 JFZ D "C6'" 1 
HETATM 19706 N "N1'" . JFZ J 2 .   ? -53.295  -83.714  11.797  1.00 130.40 ? 1001 JFZ D "N1'" 1 
HETATM 19707 O "O2'" . JFZ J 2 .   ? -54.366  -83.412  12.300  1.00 113.34 ? 1001 JFZ D "O2'" 1 
HETATM 19708 O "O3'" . JFZ J 2 .   ? -52.721  -83.023  10.970  1.00 121.61 ? 1001 JFZ D "O3'" 1 
HETATM 19709 C C1    . JFZ K 2 .   ? -66.335  10.068   -32.022 1.00 62.48  ? 1001 JFZ E C1    1 
HETATM 19710 C C2    . JFZ K 2 .   ? -65.552  9.729    -30.774 1.00 53.57  ? 1001 JFZ E C2    1 
HETATM 19711 O O2    . JFZ K 2 .   ? -66.282  10.126   -29.629 1.00 38.57  ? 1001 JFZ E O2    1 
HETATM 19712 C C3    . JFZ K 2 .   ? -65.260  8.260    -30.803 1.00 41.94  ? 1001 JFZ E C3    1 
HETATM 19713 O O3    . JFZ K 2 .   ? -64.509  7.888    -29.674 1.00 38.60  ? 1001 JFZ E O3    1 
HETATM 19714 C C4    . JFZ K 2 .   ? -64.445  7.954    -32.022 1.00 45.20  ? 1001 JFZ E C4    1 
HETATM 19715 O O4    . JFZ K 2 .   ? -63.252  8.681    -31.929 1.00 46.37  ? 1001 JFZ E O4    1 
HETATM 19716 C C5    . JFZ K 2 .   ? -65.201  8.369    -33.273 1.00 40.86  ? 1001 JFZ E C5    1 
HETATM 19717 C C6    . JFZ K 2 .   ? -64.375  8.242    -34.522 1.00 37.09  ? 1001 JFZ E C6    1 
HETATM 19718 O O5    . JFZ K 2 .   ? -65.573  9.753    -33.170 1.00 45.60  ? 1001 JFZ E O5    1 
HETATM 19719 O O1    . JFZ K 2 .   ? -67.438  9.210    -32.000 1.00 69.21  ? 1001 JFZ E O1    1 
HETATM 19720 C "C1'" . JFZ K 2 .   ? -68.598  9.589    -32.634 1.00 88.25  ? 1001 JFZ E "C1'" 1 
HETATM 19721 C "C2'" . JFZ K 2 .   ? -69.563  8.612    -32.758 1.00 111.30 ? 1001 JFZ E "C2'" 1 
HETATM 19722 C "C3'" . JFZ K 2 .   ? -70.751  8.894    -33.393 1.00 132.49 ? 1001 JFZ E "C3'" 1 
HETATM 19723 C "C4'" . JFZ K 2 .   ? -70.948  10.173   -33.897 1.00 130.95 ? 1001 JFZ E "C4'" 1 
HETATM 19724 C "C5'" . JFZ K 2 .   ? -69.984  11.165   -33.766 1.00 109.47 ? 1001 JFZ E "C5'" 1 
HETATM 19725 C "C6'" . JFZ K 2 .   ? -68.804  10.859   -33.126 1.00 92.68  ? 1001 JFZ E "C6'" 1 
HETATM 19726 N "N1'" . JFZ K 2 .   ? -72.200  10.477   -34.569 1.00 130.00 ? 1001 JFZ E "N1'" 1 
HETATM 19727 O "O2'" . JFZ K 2 .   ? -72.341  11.589   -35.047 1.00 123.81 ? 1001 JFZ E "O2'" 1 
HETATM 19728 O "O3'" . JFZ K 2 .   ? -73.046  9.604    -34.631 1.00 115.34 ? 1001 JFZ E "O3'" 1 
HETATM 19729 C C1    . JFZ L 2 .   ? -62.448  -34.088  -44.356 1.00 62.59  ? 1001 JFZ F C1    1 
HETATM 19730 C C2    . JFZ L 2 .   ? -61.135  -33.839  -45.063 1.00 51.01  ? 1001 JFZ F C2    1 
HETATM 19731 O O2    . JFZ L 2 .   ? -61.227  -34.258  -46.422 1.00 42.45  ? 1001 JFZ F O2    1 
HETATM 19732 C C3    . JFZ L 2 .   ? -60.864  -32.365  -44.966 1.00 42.64  ? 1001 JFZ F C3    1 
HETATM 19733 O O3    . JFZ L 2 .   ? -59.684  -32.053  -45.685 1.00 34.50  ? 1001 JFZ F O3    1 
HETATM 19734 C C4    . JFZ L 2 .   ? -60.710  -31.971  -43.514 1.00 43.86  ? 1001 JFZ F C4    1 
HETATM 19735 O O4    . JFZ L 2 .   ? -59.595  -32.648  -42.941 1.00 33.23  ? 1001 JFZ F O4    1 
HETATM 19736 C C5    . JFZ L 2 .   ? -61.977  -32.325  -42.747 1.00 41.14  ? 1001 JFZ F C5    1 
HETATM 19737 C C6    . JFZ L 2 .   ? -61.781  -32.186  -41.256 1.00 40.05  ? 1001 JFZ F C6    1 
HETATM 19738 O O5    . JFZ L 2 .   ? -62.351  -33.703  -42.996 1.00 53.40  ? 1001 JFZ F O5    1 
HETATM 19739 O O1    . JFZ L 2 .   ? -63.392  -33.289  -45.041 1.00 80.65  ? 1001 JFZ F O1    1 
HETATM 19740 C "C1'" . JFZ L 2 .   ? -64.723  -33.656  -44.986 1.00 90.75  ? 1001 JFZ F "C1'" 1 
HETATM 19741 C "C2'" . JFZ L 2 .   ? -65.670  -32.895  -45.651 1.00 84.68  ? 1001 JFZ F "C2'" 1 
HETATM 19742 C "C3'" . JFZ L 2 .   ? -67.000  -33.256  -45.601 1.00 96.08  ? 1001 JFZ F "C3'" 1 
HETATM 19743 C "C4'" . JFZ L 2 .   ? -67.357  -34.390  -44.877 1.00 111.62 ? 1001 JFZ F "C4'" 1 
HETATM 19744 C "C5'" . JFZ L 2 .   ? -66.411  -35.161  -44.207 1.00 91.42  ? 1001 JFZ F "C5'" 1 
HETATM 19745 C "C6'" . JFZ L 2 .   ? -65.086  -34.783  -44.268 1.00 83.79  ? 1001 JFZ F "C6'" 1 
HETATM 19746 N "N1'" . JFZ L 2 .   ? -68.759  -34.781  -44.818 1.00 115.25 ? 1001 JFZ F "N1'" 1 
HETATM 19747 O "O2'" . JFZ L 2 .   ? -69.576  -34.095  -45.411 1.00 103.53 ? 1001 JFZ F "O2'" 1 
HETATM 19748 O "O3'" . JFZ L 2 .   ? -69.055  -35.778  -44.178 1.00 118.54 ? 1001 JFZ F "O3'" 1 
HETATM 19749 O O     . HOH M 3 .   ? -57.023  -58.560  4.436   1.00 41.41  ? 1101 HOH A O     1 
HETATM 19750 O O     . HOH M 3 .   ? -41.348  -64.287  -28.089 1.00 20.17  ? 1102 HOH A O     1 
HETATM 19751 O O     . HOH M 3 .   ? -28.730  -34.401  18.656  1.00 43.91  ? 1103 HOH A O     1 
HETATM 19752 O O     . HOH M 3 .   ? -27.372  -43.130  -2.235  1.00 31.33  ? 1104 HOH A O     1 
HETATM 19753 O O     . HOH M 3 .   ? -43.214  -77.360  -7.181  1.00 43.84  ? 1105 HOH A O     1 
HETATM 19754 O O     . HOH M 3 .   ? -62.481  -66.262  -28.625 1.00 46.51  ? 1106 HOH A O     1 
HETATM 19755 O O     . HOH M 3 .   ? -39.680  -34.624  16.935  1.00 32.34  ? 1107 HOH A O     1 
HETATM 19756 O O     . HOH M 3 .   ? -49.270  -23.973  -2.031  1.00 43.02  ? 1108 HOH A O     1 
HETATM 19757 O O     . HOH M 3 .   ? -39.703  -72.418  -26.264 1.00 33.74  ? 1109 HOH A O     1 
HETATM 19758 O O     . HOH M 3 .   ? -35.259  -53.758  -26.043 1.00 20.68  ? 1110 HOH A O     1 
HETATM 19759 O O     . HOH M 3 .   ? -56.607  -43.397  18.034  1.00 30.63  ? 1111 HOH A O     1 
HETATM 19760 O O     . HOH M 3 .   ? -52.249  -69.403  -10.041 1.00 26.26  ? 1112 HOH A O     1 
HETATM 19761 O O     . HOH M 3 .   ? -55.828  -49.790  13.478  1.00 38.29  ? 1113 HOH A O     1 
HETATM 19762 O O     . HOH M 3 .   ? -47.198  -26.327  18.561  1.00 42.70  ? 1114 HOH A O     1 
HETATM 19763 O O     . HOH M 3 .   ? -36.108  -62.917  -16.780 1.00 25.80  ? 1115 HOH A O     1 
HETATM 19764 O O     . HOH M 3 .   ? -37.321  -46.516  -1.982  1.00 36.69  ? 1116 HOH A O     1 
HETATM 19765 O O     . HOH M 3 .   ? -61.956  -48.461  22.235  1.00 33.08  ? 1117 HOH A O     1 
HETATM 19766 O O     . HOH M 3 .   ? -43.100  -37.295  6.965   1.00 21.19  ? 1118 HOH A O     1 
HETATM 19767 O O     . HOH M 3 .   ? -61.861  -50.615  17.853  1.00 38.27  ? 1119 HOH A O     1 
HETATM 19768 O O     . HOH M 3 .   ? -40.520  -73.472  -29.408 1.00 33.35  ? 1120 HOH A O     1 
HETATM 19769 O O     . HOH M 3 .   ? -37.215  -38.915  2.439   1.00 16.38  ? 1121 HOH A O     1 
HETATM 19770 O O     . HOH M 3 .   ? -46.281  -28.380  -5.792  1.00 32.35  ? 1122 HOH A O     1 
HETATM 19771 O O     . HOH M 3 .   ? -43.778  -51.108  -21.824 1.00 25.35  ? 1123 HOH A O     1 
HETATM 19772 O O     . HOH M 3 .   ? -38.691  -64.309  -13.482 1.00 21.09  ? 1124 HOH A O     1 
HETATM 19773 O O     . HOH M 3 .   ? -62.343  -56.345  -6.139  1.00 35.81  ? 1125 HOH A O     1 
HETATM 19774 O O     . HOH M 3 .   ? -51.319  -36.025  14.946  1.00 30.20  ? 1126 HOH A O     1 
HETATM 19775 O O     . HOH M 3 .   ? -32.825  -57.951  -5.109  1.00 19.73  ? 1127 HOH A O     1 
HETATM 19776 O O     . HOH M 3 .   ? -66.879  -49.763  7.107   1.00 25.79  ? 1128 HOH A O     1 
HETATM 19777 O O     . HOH M 3 .   ? -35.925  -56.728  2.963   1.00 41.02  ? 1129 HOH A O     1 
HETATM 19778 O O     . HOH M 3 .   ? -62.617  -49.531  -10.335 1.00 36.71  ? 1130 HOH A O     1 
HETATM 19779 O O     . HOH M 3 .   ? -26.783  -36.834  8.046   1.00 34.33  ? 1131 HOH A O     1 
HETATM 19780 O O     . HOH M 3 .   ? -66.869  -45.952  14.507  1.00 31.65  ? 1132 HOH A O     1 
HETATM 19781 O O     . HOH M 3 .   ? -32.446  -41.318  -12.535 1.00 30.90  ? 1133 HOH A O     1 
HETATM 19782 O O     . HOH M 3 .   ? -46.981  -33.815  16.555  1.00 29.10  ? 1134 HOH A O     1 
HETATM 19783 O O     . HOH M 3 .   ? -54.530  -25.132  3.135   1.00 38.09  ? 1135 HOH A O     1 
HETATM 19784 O O     . HOH M 3 .   ? -55.146  -80.267  -26.658 1.00 35.92  ? 1136 HOH A O     1 
HETATM 19785 O O     . HOH M 3 .   ? -28.257  -45.980  16.886  1.00 37.20  ? 1137 HOH A O     1 
HETATM 19786 O O     . HOH M 3 .   ? -38.236  -64.323  -16.893 1.00 35.01  ? 1138 HOH A O     1 
HETATM 19787 O O     . HOH M 3 .   ? -33.872  -24.946  -0.095  1.00 38.90  ? 1139 HOH A O     1 
HETATM 19788 O O     . HOH M 3 .   ? -57.012  -57.060  -1.433  1.00 21.25  ? 1140 HOH A O     1 
HETATM 19789 O O     . HOH M 3 .   ? -32.604  -38.994  7.914   1.00 21.45  ? 1141 HOH A O     1 
HETATM 19790 O O     . HOH M 3 .   ? -50.387  -49.952  -21.669 1.00 35.94  ? 1142 HOH A O     1 
HETATM 19791 O O     . HOH M 3 .   ? -26.101  -58.991  -25.712 1.00 20.29  ? 1143 HOH A O     1 
HETATM 19792 O O     . HOH M 3 .   ? -47.629  -29.870  18.318  1.00 35.90  ? 1144 HOH A O     1 
HETATM 19793 O O     . HOH M 3 .   ? -40.650  -58.554  -26.073 1.00 26.52  ? 1145 HOH A O     1 
HETATM 19794 O O     . HOH M 3 .   ? -32.802  -54.076  0.394   1.00 23.96  ? 1146 HOH A O     1 
HETATM 19795 O O     . HOH M 3 .   ? -61.755  -44.164  -1.451  1.00 23.99  ? 1147 HOH A O     1 
HETATM 19796 O O     . HOH M 3 .   ? -58.118  -81.087  -11.965 1.00 26.29  ? 1148 HOH A O     1 
HETATM 19797 O O     . HOH M 3 .   ? -26.341  -37.752  10.580  1.00 40.24  ? 1149 HOH A O     1 
HETATM 19798 O O     . HOH M 3 .   ? -50.612  -29.003  -7.164  1.00 35.96  ? 1150 HOH A O     1 
HETATM 19799 O O     . HOH M 3 .   ? -54.183  -24.725  19.627  1.00 40.99  ? 1151 HOH A O     1 
HETATM 19800 O O     . HOH M 3 .   ? -43.308  -35.827  9.591   1.00 26.63  ? 1152 HOH A O     1 
HETATM 19801 O O     . HOH M 3 .   ? -55.778  -27.478  6.703   1.00 23.15  ? 1153 HOH A O     1 
HETATM 19802 O O     . HOH M 3 .   ? -20.550  -42.059  0.767   1.00 28.95  ? 1154 HOH A O     1 
HETATM 19803 O O     . HOH M 3 .   ? -52.713  -69.959  -29.266 1.00 20.36  ? 1155 HOH A O     1 
HETATM 19804 O O     . HOH M 3 .   ? -50.120  -54.697  -23.153 1.00 32.99  ? 1156 HOH A O     1 
HETATM 19805 O O     . HOH M 3 .   ? -36.854  -69.658  -21.282 1.00 22.41  ? 1157 HOH A O     1 
HETATM 19806 O O     . HOH M 3 .   ? -66.074  -54.827  2.336   1.00 28.55  ? 1158 HOH A O     1 
HETATM 19807 O O     . HOH M 3 .   ? -40.815  -33.024  -6.379  1.00 27.80  ? 1159 HOH A O     1 
HETATM 19808 O O     . HOH M 3 .   ? -56.099  -90.964  -13.555 1.00 32.72  ? 1160 HOH A O     1 
HETATM 19809 O O     . HOH M 3 .   ? -59.864  -43.741  -8.860  1.00 34.91  ? 1161 HOH A O     1 
HETATM 19810 O O     . HOH M 3 .   ? -33.009  -32.185  -3.788  1.00 34.96  ? 1162 HOH A O     1 
HETATM 19811 O O     . HOH M 3 .   ? -40.432  -67.445  -30.291 1.00 30.09  ? 1163 HOH A O     1 
HETATM 19812 O O     . HOH M 3 .   ? -34.480  -39.759  5.586   1.00 22.98  ? 1164 HOH A O     1 
HETATM 19813 O O     . HOH M 3 .   ? -57.631  -49.069  -11.819 1.00 32.22  ? 1165 HOH A O     1 
HETATM 19814 O O     . HOH M 3 .   ? -53.866  -67.245  -8.863  1.00 43.43  ? 1166 HOH A O     1 
HETATM 19815 O O     . HOH M 3 .   ? -33.666  -34.491  23.432  1.00 39.89  ? 1167 HOH A O     1 
HETATM 19816 O O     . HOH M 3 .   ? -40.882  -23.230  -1.520  1.00 47.40  ? 1168 HOH A O     1 
HETATM 19817 O O     . HOH M 3 .   ? -62.520  -74.019  -15.966 1.00 51.76  ? 1169 HOH A O     1 
HETATM 19818 O O     . HOH M 3 .   ? -44.911  -69.523  -30.238 1.00 20.90  ? 1170 HOH A O     1 
HETATM 19819 O O     . HOH M 3 .   ? -45.954  -73.793  -15.000 1.00 26.12  ? 1171 HOH A O     1 
HETATM 19820 O O     . HOH M 3 .   ? -57.095  -76.856  -20.011 1.00 31.86  ? 1172 HOH A O     1 
HETATM 19821 O O     . HOH M 3 .   ? -62.074  -58.102  -12.055 1.00 37.27  ? 1173 HOH A O     1 
HETATM 19822 O O     . HOH M 3 .   ? -37.569  -28.712  2.343   1.00 28.17  ? 1174 HOH A O     1 
HETATM 19823 O O     . HOH M 3 .   ? -29.404  -70.674  -30.583 1.00 41.86  ? 1175 HOH A O     1 
HETATM 19824 O O     . HOH M 3 .   ? -55.255  -59.449  -7.559  1.00 19.96  ? 1176 HOH A O     1 
HETATM 19825 O O     . HOH M 3 .   ? -41.305  -70.604  -12.884 1.00 28.51  ? 1177 HOH A O     1 
HETATM 19826 O O     . HOH M 3 .   ? -36.238  -57.248  -28.449 1.00 28.79  ? 1178 HOH A O     1 
HETATM 19827 O O     . HOH M 3 .   ? -53.306  -23.207  4.372   1.00 44.40  ? 1179 HOH A O     1 
HETATM 19828 O O     . HOH M 3 .   ? -63.670  -39.974  0.015   1.00 36.09  ? 1180 HOH A O     1 
HETATM 19829 O O     . HOH M 3 .   ? -60.748  -33.058  3.241   1.00 25.93  ? 1181 HOH A O     1 
HETATM 19830 O O     . HOH M 3 .   ? -61.745  -65.087  -23.762 1.00 29.09  ? 1182 HOH A O     1 
HETATM 19831 O O     . HOH M 3 .   ? -36.731  -32.009  4.891   1.00 28.37  ? 1183 HOH A O     1 
HETATM 19832 O O     . HOH M 3 .   ? -40.231  -39.843  11.742  1.00 23.56  ? 1184 HOH A O     1 
HETATM 19833 O O     . HOH M 3 .   ? -40.821  -60.082  -30.776 1.00 35.06  ? 1185 HOH A O     1 
HETATM 19834 O O     . HOH M 3 .   ? -59.976  -41.258  19.159  1.00 34.63  ? 1186 HOH A O     1 
HETATM 19835 O O     . HOH M 3 .   ? -34.346  -45.050  1.185   1.00 27.79  ? 1187 HOH A O     1 
HETATM 19836 O O     . HOH M 3 .   ? -57.909  -49.506  21.084  1.00 34.31  ? 1188 HOH A O     1 
HETATM 19837 O O     . HOH M 3 .   ? -27.796  -57.588  0.191   1.00 33.24  ? 1189 HOH A O     1 
HETATM 19838 O O     . HOH M 3 .   ? -36.537  -38.886  12.722  1.00 28.24  ? 1190 HOH A O     1 
HETATM 19839 O O     . HOH M 3 .   ? -32.382  -43.860  0.055   1.00 28.56  ? 1191 HOH A O     1 
HETATM 19840 O O     . HOH M 3 .   ? -33.607  -35.295  -7.993  1.00 30.35  ? 1192 HOH A O     1 
HETATM 19841 O O     . HOH M 3 .   ? -64.428  -71.901  -24.089 1.00 44.47  ? 1193 HOH A O     1 
HETATM 19842 O O     . HOH M 3 .   ? -31.754  -34.838  1.331   1.00 27.38  ? 1194 HOH A O     1 
HETATM 19843 O O     . HOH M 3 .   ? -66.299  -39.657  16.669  1.00 35.23  ? 1195 HOH A O     1 
HETATM 19844 O O     . HOH M 3 .   ? -57.188  -43.934  -9.525  1.00 31.47  ? 1196 HOH A O     1 
HETATM 19845 O O     . HOH M 3 .   ? -41.987  -30.777  21.904  1.00 43.14  ? 1197 HOH A O     1 
HETATM 19846 O O     . HOH M 3 .   ? -51.546  -44.886  -13.824 1.00 42.76  ? 1198 HOH A O     1 
HETATM 19847 O O     . HOH M 3 .   ? -66.198  -48.627  14.666  1.00 31.05  ? 1199 HOH A O     1 
HETATM 19848 O O     . HOH M 3 .   ? -53.503  -66.910  -4.591  1.00 33.02  ? 1200 HOH A O     1 
HETATM 19849 O O     . HOH M 3 .   ? -29.436  -44.488  -1.330  1.00 28.13  ? 1201 HOH A O     1 
HETATM 19850 O O     . HOH M 3 .   ? -57.021  -33.100  -15.477 1.00 42.83  ? 1202 HOH A O     1 
HETATM 19851 O O     . HOH M 3 .   ? -56.168  -56.034  -3.999  1.00 17.83  ? 1203 HOH A O     1 
HETATM 19852 O O     . HOH M 3 .   ? -58.832  -38.239  -7.603  1.00 34.96  ? 1204 HOH A O     1 
HETATM 19853 O O     . HOH M 3 .   ? -45.445  -60.207  -21.384 1.00 19.38  ? 1205 HOH A O     1 
HETATM 19854 O O     . HOH M 3 .   ? -44.813  -67.012  -7.863  1.00 37.90  ? 1206 HOH A O     1 
HETATM 19855 O O     . HOH M 3 .   ? -31.235  -65.547  -21.022 1.00 41.41  ? 1207 HOH A O     1 
HETATM 19856 O O     . HOH M 3 .   ? -35.568  -49.653  8.110   1.00 24.18  ? 1208 HOH A O     1 
HETATM 19857 O O     . HOH M 3 .   ? -50.455  -49.775  -16.585 1.00 39.77  ? 1209 HOH A O     1 
HETATM 19858 O O     . HOH M 3 .   ? -50.774  -36.845  -17.830 1.00 42.98  ? 1210 HOH A O     1 
HETATM 19859 O O     . HOH M 3 .   ? -35.960  -68.858  -9.689  1.00 44.44  ? 1211 HOH A O     1 
HETATM 19860 O O     . HOH M 3 .   ? -63.157  -54.302  9.346   1.00 34.74  ? 1212 HOH A O     1 
HETATM 19861 O O     . HOH M 3 .   ? -38.297  -70.219  -27.222 1.00 22.63  ? 1213 HOH A O     1 
HETATM 19862 O O     . HOH M 3 .   ? -55.345  -45.655  13.704  1.00 28.94  ? 1214 HOH A O     1 
HETATM 19863 O O     . HOH M 3 .   ? -45.447  -71.643  -28.358 1.00 21.19  ? 1215 HOH A O     1 
HETATM 19864 O O     . HOH M 3 .   ? -57.931  -87.603  -18.804 1.00 38.15  ? 1216 HOH A O     1 
HETATM 19865 O O     . HOH M 3 .   ? -51.631  -80.782  -21.565 1.00 23.71  ? 1217 HOH A O     1 
HETATM 19866 O O     . HOH M 3 .   ? -43.055  -36.210  -13.888 1.00 29.91  ? 1218 HOH A O     1 
HETATM 19867 O O     . HOH M 3 .   ? -59.744  -36.856  -10.171 1.00 42.40  ? 1219 HOH A O     1 
HETATM 19868 O O     . HOH M 3 .   ? -39.028  -65.479  -28.908 1.00 27.26  ? 1220 HOH A O     1 
HETATM 19869 O O     . HOH M 3 .   ? -54.082  -58.051  -10.964 1.00 36.08  ? 1221 HOH A O     1 
HETATM 19870 O O     . HOH M 3 .   ? -53.103  -90.154  -14.937 1.00 23.47  ? 1222 HOH A O     1 
HETATM 19871 O O     . HOH M 3 .   ? -40.969  -45.820  -18.196 1.00 39.40  ? 1223 HOH A O     1 
HETATM 19872 O O     . HOH M 3 .   ? -65.763  -39.545  1.181   1.00 36.81  ? 1224 HOH A O     1 
HETATM 19873 O O     . HOH M 3 .   ? -48.740  -81.805  -24.061 1.00 23.99  ? 1225 HOH A O     1 
HETATM 19874 O O     . HOH M 3 .   ? -69.431  -48.652  4.415   1.00 32.03  ? 1226 HOH A O     1 
HETATM 19875 O O     . HOH M 3 .   ? -36.722  -54.219  2.711   1.00 30.17  ? 1227 HOH A O     1 
HETATM 19876 O O     . HOH M 3 .   ? -56.427  -54.690  -15.629 1.00 22.29  ? 1228 HOH A O     1 
HETATM 19877 O O     . HOH M 3 .   ? -34.437  -63.600  -30.533 1.00 23.50  ? 1229 HOH A O     1 
HETATM 19878 O O     . HOH M 3 .   ? -63.081  -30.041  2.258   1.00 29.97  ? 1230 HOH A O     1 
HETATM 19879 O O     . HOH M 3 .   ? -37.634  -72.957  -18.424 1.00 28.77  ? 1231 HOH A O     1 
HETATM 19880 O O     . HOH M 3 .   ? -62.759  -58.376  -14.692 1.00 33.80  ? 1232 HOH A O     1 
HETATM 19881 O O     . HOH M 3 .   ? -55.771  -86.728  -21.910 1.00 33.70  ? 1233 HOH A O     1 
HETATM 19882 O O     . HOH M 3 .   ? -31.602  -73.618  -25.062 1.00 45.96  ? 1234 HOH A O     1 
HETATM 19883 O O     . HOH M 3 .   ? -38.318  -70.705  -23.339 1.00 20.52  ? 1235 HOH A O     1 
HETATM 19884 O O     . HOH M 3 .   ? -66.350  -36.259  1.830   1.00 31.11  ? 1236 HOH A O     1 
HETATM 19885 O O     . HOH M 3 .   ? -47.045  -47.626  -17.086 1.00 29.75  ? 1237 HOH A O     1 
HETATM 19886 O O     . HOH M 3 .   ? -38.807  -34.369  -8.285  1.00 31.31  ? 1238 HOH A O     1 
HETATM 19887 O O     . HOH M 3 .   ? -57.129  -30.536  -9.367  1.00 42.41  ? 1239 HOH A O     1 
HETATM 19888 O O     . HOH M 3 .   ? -55.095  -44.823  16.134  1.00 24.50  ? 1240 HOH A O     1 
HETATM 19889 O O     . HOH M 3 .   ? -32.778  -52.823  7.944   1.00 28.69  ? 1241 HOH A O     1 
HETATM 19890 O O     . HOH M 3 .   ? -39.327  -53.714  1.430   1.00 28.25  ? 1242 HOH A O     1 
HETATM 19891 O O     . HOH M 3 .   ? -56.598  -44.443  26.656  1.00 33.83  ? 1243 HOH A O     1 
HETATM 19892 O O     . HOH M 3 .   ? -68.210  -46.000  0.530   1.00 30.56  ? 1244 HOH A O     1 
HETATM 19893 O O     . HOH M 3 .   ? -44.763  -61.682  -32.548 1.00 48.76  ? 1245 HOH A O     1 
HETATM 19894 O O     . HOH M 3 .   ? -60.341  -48.994  19.978  1.00 36.54  ? 1246 HOH A O     1 
HETATM 19895 O O     . HOH M 3 .   ? -45.524  -79.789  -6.555  1.00 46.34  ? 1247 HOH A O     1 
HETATM 19896 O O     . HOH M 3 .   ? -47.512  -65.472  -33.741 1.00 32.68  ? 1248 HOH A O     1 
HETATM 19897 O O     . HOH M 3 .   ? -44.010  -63.346  -8.364  1.00 39.11  ? 1249 HOH A O     1 
HETATM 19898 O O     . HOH M 3 .   ? -30.733  -37.763  -6.419  1.00 40.93  ? 1250 HOH A O     1 
HETATM 19899 O O     . HOH M 3 .   ? -50.973  -23.999  12.729  1.00 37.54  ? 1251 HOH A O     1 
HETATM 19900 O O     . HOH M 3 .   ? -68.779  -48.369  -0.682  1.00 25.02  ? 1252 HOH A O     1 
HETATM 19901 O O     . HOH M 3 .   ? -45.842  -65.015  -6.928  1.00 38.48  ? 1253 HOH A O     1 
HETATM 19902 O O     . HOH M 3 .   ? -36.901  -78.204  -28.266 1.00 26.79  ? 1254 HOH A O     1 
HETATM 19903 O O     . HOH M 3 .   ? -51.637  -48.338  13.134  1.00 57.47  ? 1255 HOH A O     1 
HETATM 19904 O O     . HOH M 3 .   ? -57.398  -40.630  18.211  1.00 37.66  ? 1256 HOH A O     1 
HETATM 19905 O O     . HOH M 3 .   ? -69.446  -50.363  11.269  1.00 46.85  ? 1257 HOH A O     1 
HETATM 19906 O O     . HOH M 3 .   ? -68.493  -45.511  12.354  1.00 34.72  ? 1258 HOH A O     1 
HETATM 19907 O O     . HOH M 3 .   ? -49.037  -73.738  -7.934  1.00 41.53  ? 1259 HOH A O     1 
HETATM 19908 O O     . HOH M 3 .   ? -62.041  -46.266  -3.284  1.00 25.94  ? 1260 HOH A O     1 
HETATM 19909 O O     . HOH M 3 .   ? -51.571  -74.844  -30.375 1.00 29.66  ? 1261 HOH A O     1 
HETATM 19910 O O     . HOH M 3 .   ? -47.989  -38.844  -16.850 1.00 41.33  ? 1262 HOH A O     1 
HETATM 19911 O O     . HOH M 3 .   ? -46.284  -23.980  -5.178  1.00 50.94  ? 1263 HOH A O     1 
HETATM 19912 O O     . HOH M 3 .   ? -56.319  -28.498  -3.065  1.00 43.86  ? 1264 HOH A O     1 
HETATM 19913 O O     . HOH M 3 .   ? -61.848  -60.966  -11.730 1.00 35.78  ? 1265 HOH A O     1 
HETATM 19914 O O     . HOH M 3 .   ? -66.222  -75.209  -27.556 1.00 47.88  ? 1266 HOH A O     1 
HETATM 19915 O O     . HOH M 3 .   ? -53.215  -85.377  -18.770 1.00 33.94  ? 1267 HOH A O     1 
HETATM 19916 O O     . HOH M 3 .   ? -24.737  -42.045  6.146   1.00 38.61  ? 1268 HOH A O     1 
HETATM 19917 O O     . HOH M 3 .   ? -59.488  -82.801  -23.820 1.00 37.71  ? 1269 HOH A O     1 
HETATM 19918 O O     . HOH M 3 .   ? -43.278  -67.621  -33.488 1.00 45.26  ? 1270 HOH A O     1 
HETATM 19919 O O     . HOH M 3 .   ? -60.555  -38.827  -3.578  1.00 48.23  ? 1271 HOH A O     1 
HETATM 19920 O O     . HOH M 3 .   ? -61.067  -27.508  10.277  1.00 34.54  ? 1272 HOH A O     1 
HETATM 19921 O O     . HOH M 3 .   ? -34.147  -42.103  -14.552 1.00 44.88  ? 1273 HOH A O     1 
HETATM 19922 O O     . HOH M 3 .   ? -32.935  -50.188  8.587   1.00 23.15  ? 1274 HOH A O     1 
HETATM 19923 O O     . HOH M 3 .   ? -63.976  -32.102  3.112   1.00 35.59  ? 1275 HOH A O     1 
HETATM 19924 O O     . HOH M 3 .   ? -55.064  -50.814  15.911  1.00 45.99  ? 1276 HOH A O     1 
HETATM 19925 O O     . HOH M 3 .   ? -41.737  -35.208  23.346  1.00 38.74  ? 1277 HOH A O     1 
HETATM 19926 O O     . HOH M 3 .   ? -36.134  -43.745  -2.933  1.00 34.23  ? 1278 HOH A O     1 
HETATM 19927 O O     . HOH M 3 .   ? -57.948  -68.565  -5.780  1.00 43.19  ? 1279 HOH A O     1 
HETATM 19928 O O     . HOH M 3 .   ? -36.080  -73.112  -23.101 1.00 48.31  ? 1280 HOH A O     1 
HETATM 19929 O O     . HOH M 3 .   ? -59.643  -33.736  -13.140 1.00 50.81  ? 1281 HOH A O     1 
HETATM 19930 O O     . HOH M 3 .   ? -58.663  -59.743  -4.182  1.00 33.45  ? 1282 HOH A O     1 
HETATM 19931 O O     . HOH M 3 .   ? -49.880  -71.088  -8.866  1.00 37.44  ? 1283 HOH A O     1 
HETATM 19932 O O     . HOH M 3 .   ? -59.948  -37.479  -5.326  1.00 39.27  ? 1284 HOH A O     1 
HETATM 19933 O O     . HOH M 3 .   ? -34.110  -44.234  -15.982 1.00 38.90  ? 1285 HOH A O     1 
HETATM 19934 O O     . HOH M 3 .   ? -43.639  -46.765  -19.748 1.00 42.00  ? 1286 HOH A O     1 
HETATM 19935 O O     . HOH M 3 .   ? -41.339  -40.730  -14.803 1.00 31.40  ? 1287 HOH A O     1 
HETATM 19936 O O     . HOH M 3 .   ? -64.306  -56.842  9.418   1.00 49.21  ? 1288 HOH A O     1 
HETATM 19937 O O     . HOH M 3 .   ? -29.989  -40.856  -5.815  1.00 31.12  ? 1289 HOH A O     1 
HETATM 19938 O O     . HOH M 3 .   ? -35.991  -47.532  -18.204 1.00 29.33  ? 1290 HOH A O     1 
HETATM 19939 O O     . HOH M 3 .   ? -65.318  -33.839  1.188   1.00 38.32  ? 1291 HOH A O     1 
HETATM 19940 O O     . HOH M 3 .   ? -66.049  -48.561  -7.443  1.00 40.58  ? 1292 HOH A O     1 
HETATM 19941 O O     . HOH M 3 .   ? -56.800  -84.965  -24.023 1.00 46.45  ? 1293 HOH A O     1 
HETATM 19942 O O     . HOH M 3 .   ? -44.751  -26.362  -7.160  1.00 44.81  ? 1294 HOH A O     1 
HETATM 19943 O O     . HOH M 3 .   ? -56.756  -58.129  -5.625  1.00 26.51  ? 1295 HOH A O     1 
HETATM 19944 O O     . HOH M 3 .   ? -64.637  -45.463  -4.529  1.00 36.14  ? 1296 HOH A O     1 
HETATM 19945 O O     . HOH M 3 .   ? -60.951  -39.407  21.677  1.00 41.28  ? 1297 HOH A O     1 
HETATM 19946 O O     . HOH M 3 .   ? -45.859  -52.374  -23.842 1.00 45.43  ? 1298 HOH A O     1 
HETATM 19947 O O     . HOH M 3 .   ? -58.417  -26.754  15.499  1.00 29.95  ? 1299 HOH A O     1 
HETATM 19948 O O     . HOH M 3 .   ? -58.950  -78.666  -11.202 1.00 37.01  ? 1300 HOH A O     1 
HETATM 19949 O O     . HOH M 3 .   ? -25.666  -40.302  12.157  1.00 43.75  ? 1301 HOH A O     1 
HETATM 19950 O O     . HOH M 3 .   ? -32.625  -56.675  -0.165  1.00 30.03  ? 1302 HOH A O     1 
HETATM 19951 O O     . HOH M 3 .   ? -66.935  -47.254  21.639  1.00 44.45  ? 1303 HOH A O     1 
HETATM 19952 O O     . HOH M 3 .   ? -56.203  -26.437  19.273  1.00 32.30  ? 1304 HOH A O     1 
HETATM 19953 O O     . HOH M 3 .   ? -37.111  -64.632  -30.644 1.00 25.78  ? 1305 HOH A O     1 
HETATM 19954 O O     . HOH M 3 .   ? -30.700  -41.139  -3.282  1.00 40.94  ? 1306 HOH A O     1 
HETATM 19955 O O     . HOH M 3 .   ? -62.565  -62.602  -9.941  1.00 38.11  ? 1307 HOH A O     1 
HETATM 19956 O O     . HOH M 3 .   ? -41.241  -64.138  -33.120 1.00 38.11  ? 1308 HOH A O     1 
HETATM 19957 O O     . HOH M 3 .   ? -38.384  -69.159  -29.861 1.00 44.36  ? 1309 HOH A O     1 
HETATM 19958 O O     . HOH M 3 .   ? -36.911  -66.852  -32.481 1.00 35.80  ? 1310 HOH A O     1 
HETATM 19959 O O     . HOH N 3 .   ? -16.233  -69.179  5.135   1.00 34.98  ? 1101 HOH B O     1 
HETATM 19960 O O     . HOH N 3 .   ? -31.498  -58.175  16.745  1.00 43.99  ? 1102 HOH B O     1 
HETATM 19961 O O     . HOH N 3 .   ? -20.772  -49.238  13.272  1.00 29.16  ? 1103 HOH B O     1 
HETATM 19962 O O     . HOH N 3 .   ? -2.401   -50.495  3.018   1.00 39.05  ? 1104 HOH B O     1 
HETATM 19963 O O     . HOH N 3 .   ? -30.656  -44.409  -39.960 1.00 38.98  ? 1105 HOH B O     1 
HETATM 19964 O O     . HOH N 3 .   ? -5.237   -46.885  11.687  1.00 40.84  ? 1106 HOH B O     1 
HETATM 19965 O O     . HOH N 3 .   ? -33.793  -64.013  -33.143 1.00 36.25  ? 1107 HOH B O     1 
HETATM 19966 O O     . HOH N 3 .   ? -13.299  -34.403  -32.322 1.00 38.40  ? 1108 HOH B O     1 
HETATM 19967 O O     . HOH N 3 .   ? -12.458  -51.640  -46.601 1.00 34.42  ? 1109 HOH B O     1 
HETATM 19968 O O     . HOH N 3 .   ? -25.106  -49.073  -26.526 1.00 15.67  ? 1110 HOH B O     1 
HETATM 19969 O O     . HOH N 3 .   ? -4.294   -73.041  20.722  1.00 44.23  ? 1111 HOH B O     1 
HETATM 19970 O O     . HOH N 3 .   ? -23.715  -75.274  8.602   1.00 44.72  ? 1112 HOH B O     1 
HETATM 19971 O O     . HOH N 3 .   ? -1.533   -67.064  -33.645 1.00 34.97  ? 1113 HOH B O     1 
HETATM 19972 O O     . HOH N 3 .   ? 0.414    -50.504  14.877  1.00 45.10  ? 1114 HOH B O     1 
HETATM 19973 O O     . HOH N 3 .   ? -22.582  -55.043  -40.394 1.00 25.72  ? 1115 HOH B O     1 
HETATM 19974 O O     . HOH N 3 .   ? -13.471  -55.622  -46.910 1.00 44.04  ? 1116 HOH B O     1 
HETATM 19975 O O     . HOH N 3 .   ? -0.294   -54.774  -3.108  1.00 34.78  ? 1117 HOH B O     1 
HETATM 19976 O O     . HOH N 3 .   ? -36.149  -46.989  8.272   1.00 25.01  ? 1118 HOH B O     1 
HETATM 19977 O O     . HOH N 3 .   ? -27.104  -42.606  4.897   1.00 23.36  ? 1119 HOH B O     1 
HETATM 19978 O O     . HOH N 3 .   ? -9.972   -64.660  2.500   1.00 18.64  ? 1120 HOH B O     1 
HETATM 19979 O O     . HOH N 3 .   ? -31.599  -43.193  -35.003 1.00 36.42  ? 1121 HOH B O     1 
HETATM 19980 O O     . HOH N 3 .   ? -23.529  -58.687  1.864   1.00 18.55  ? 1122 HOH B O     1 
HETATM 19981 O O     . HOH N 3 .   ? -25.037  -52.387  -18.070 1.00 33.31  ? 1123 HOH B O     1 
HETATM 19982 O O     . HOH N 3 .   ? -15.315  -54.069  -40.669 1.00 23.69  ? 1124 HOH B O     1 
HETATM 19983 O O     . HOH N 3 .   ? -28.739  -55.323  5.709   1.00 45.19  ? 1125 HOH B O     1 
HETATM 19984 O O     . HOH N 3 .   ? -16.289  -35.781  -26.664 1.00 33.78  ? 1126 HOH B O     1 
HETATM 19985 O O     . HOH N 3 .   ? -21.631  -50.518  16.779  1.00 28.49  ? 1127 HOH B O     1 
HETATM 19986 O O     . HOH N 3 .   ? -17.376  -52.150  18.172  1.00 21.05  ? 1128 HOH B O     1 
HETATM 19987 O O     . HOH N 3 .   ? -34.959  -49.611  -20.020 1.00 33.61  ? 1129 HOH B O     1 
HETATM 19988 O O     . HOH N 3 .   ? -23.686  -56.682  4.617   1.00 31.52  ? 1130 HOH B O     1 
HETATM 19989 O O     . HOH N 3 .   ? -18.974  -50.987  -34.010 1.00 19.15  ? 1131 HOH B O     1 
HETATM 19990 O O     . HOH N 3 .   ? -20.626  -58.422  -45.682 1.00 31.20  ? 1132 HOH B O     1 
HETATM 19991 O O     . HOH N 3 .   ? -29.527  -59.240  -8.578  1.00 25.93  ? 1133 HOH B O     1 
HETATM 19992 O O     . HOH N 3 .   ? -0.514   -52.872  10.356  1.00 30.13  ? 1134 HOH B O     1 
HETATM 19993 O O     . HOH N 3 .   ? -23.194  -65.829  4.999   1.00 41.02  ? 1135 HOH B O     1 
HETATM 19994 O O     . HOH N 3 .   ? -21.582  -46.255  7.898   1.00 28.38  ? 1136 HOH B O     1 
HETATM 19995 O O     . HOH N 3 .   ? -22.470  -56.796  16.983  1.00 35.58  ? 1137 HOH B O     1 
HETATM 19996 O O     . HOH N 3 .   ? -28.796  -37.115  -33.347 1.00 34.01  ? 1138 HOH B O     1 
HETATM 19997 O O     . HOH N 3 .   ? -24.001  -54.519  16.334  1.00 20.53  ? 1139 HOH B O     1 
HETATM 19998 O O     . HOH N 3 .   ? -5.404   -44.835  -14.123 1.00 31.38  ? 1140 HOH B O     1 
HETATM 19999 O O     . HOH N 3 .   ? -16.048  -32.910  -24.382 1.00 46.19  ? 1141 HOH B O     1 
HETATM 20000 O O     . HOH N 3 .   ? -6.638   -42.682  -37.209 1.00 25.68  ? 1142 HOH B O     1 
HETATM 20001 O O     . HOH N 3 .   ? -18.318  -43.158  0.180   1.00 28.73  ? 1143 HOH B O     1 
HETATM 20002 O O     . HOH N 3 .   ? -21.649  -55.612  19.917  1.00 31.09  ? 1144 HOH B O     1 
HETATM 20003 O O     . HOH N 3 .   ? -5.788   -79.264  18.607  1.00 28.80  ? 1145 HOH B O     1 
HETATM 20004 O O     . HOH N 3 .   ? -32.821  -51.338  -19.818 1.00 30.04  ? 1146 HOH B O     1 
HETATM 20005 O O     . HOH N 3 .   ? -29.396  -59.577  -15.261 1.00 20.82  ? 1147 HOH B O     1 
HETATM 20006 O O     . HOH N 3 .   ? -1.754   -44.613  -30.784 1.00 24.41  ? 1148 HOH B O     1 
HETATM 20007 O O     . HOH N 3 .   ? -4.558   -47.781  -8.761  1.00 36.12  ? 1149 HOH B O     1 
HETATM 20008 O O     . HOH N 3 .   ? -21.638  -38.973  -23.468 1.00 27.43  ? 1150 HOH B O     1 
HETATM 20009 O O     . HOH N 3 .   ? -15.495  -43.209  -5.886  1.00 29.47  ? 1151 HOH B O     1 
HETATM 20010 O O     . HOH N 3 .   ? -0.203   -56.876  -8.662  1.00 33.93  ? 1152 HOH B O     1 
HETATM 20011 O O     . HOH N 3 .   ? -25.467  -58.019  11.415  1.00 25.35  ? 1153 HOH B O     1 
HETATM 20012 O O     . HOH N 3 .   ? -8.127   -38.828  -36.163 1.00 36.43  ? 1154 HOH B O     1 
HETATM 20013 O O     . HOH N 3 .   ? -23.669  -61.629  -21.405 1.00 35.57  ? 1155 HOH B O     1 
HETATM 20014 O O     . HOH N 3 .   ? -1.717   -61.075  -37.690 1.00 29.59  ? 1156 HOH B O     1 
HETATM 20015 O O     . HOH N 3 .   ? -16.646  -67.792  14.520  1.00 37.53  ? 1157 HOH B O     1 
HETATM 20016 O O     . HOH N 3 .   ? -7.020   -58.551  -5.714  1.00 21.35  ? 1158 HOH B O     1 
HETATM 20017 O O     . HOH N 3 .   ? -29.718  -52.866  -30.622 1.00 19.10  ? 1159 HOH B O     1 
HETATM 20018 O O     . HOH N 3 .   ? -11.818  -45.393  -4.979  1.00 32.11  ? 1160 HOH B O     1 
HETATM 20019 O O     . HOH N 3 .   ? 3.045    -67.195  -11.916 1.00 33.31  ? 1161 HOH B O     1 
HETATM 20020 O O     . HOH N 3 .   ? -16.869  -62.049  -16.576 1.00 37.75  ? 1162 HOH B O     1 
HETATM 20021 O O     . HOH N 3 .   ? -29.547  -40.149  -25.791 1.00 36.69  ? 1163 HOH B O     1 
HETATM 20022 O O     . HOH N 3 .   ? -8.353   -63.816  0.168   1.00 34.77  ? 1164 HOH B O     1 
HETATM 20023 O O     . HOH N 3 .   ? 0.856    -65.017  -22.058 1.00 35.13  ? 1165 HOH B O     1 
HETATM 20024 O O     . HOH N 3 .   ? -5.267   -60.513  -12.149 1.00 21.93  ? 1166 HOH B O     1 
HETATM 20025 O O     . HOH N 3 .   ? -34.364  -62.247  -13.007 1.00 33.70  ? 1167 HOH B O     1 
HETATM 20026 O O     . HOH N 3 .   ? -6.073   -58.098  -10.722 1.00 20.01  ? 1168 HOH B O     1 
HETATM 20027 O O     . HOH N 3 .   ? -27.826  -52.012  -28.393 1.00 21.05  ? 1169 HOH B O     1 
HETATM 20028 O O     . HOH N 3 .   ? -23.293  -49.975  14.528  1.00 30.36  ? 1170 HOH B O     1 
HETATM 20029 O O     . HOH N 3 .   ? -30.007  -51.559  -21.539 1.00 21.86  ? 1171 HOH B O     1 
HETATM 20030 O O     . HOH N 3 .   ? -12.054  -45.077  3.355   1.00 30.55  ? 1172 HOH B O     1 
HETATM 20031 O O     . HOH N 3 .   ? -24.909  -41.257  -32.796 1.00 36.26  ? 1173 HOH B O     1 
HETATM 20032 O O     . HOH N 3 .   ? -21.574  -64.573  14.007  1.00 33.32  ? 1174 HOH B O     1 
HETATM 20033 O O     . HOH N 3 .   ? 4.856    -59.960  -22.916 1.00 25.79  ? 1175 HOH B O     1 
HETATM 20034 O O     . HOH N 3 .   ? -5.022   -64.331  14.841  1.00 27.14  ? 1176 HOH B O     1 
HETATM 20035 O O     . HOH N 3 .   ? -5.449   -61.880  -35.767 1.00 30.95  ? 1177 HOH B O     1 
HETATM 20036 O O     . HOH N 3 .   ? -25.747  -55.723  3.758   1.00 33.74  ? 1178 HOH B O     1 
HETATM 20037 O O     . HOH N 3 .   ? -11.876  -35.062  -25.324 1.00 31.90  ? 1179 HOH B O     1 
HETATM 20038 O O     . HOH N 3 .   ? -4.102   -72.550  11.094  1.00 24.90  ? 1180 HOH B O     1 
HETATM 20039 O O     . HOH N 3 .   ? -25.602  -45.386  -32.715 1.00 34.10  ? 1181 HOH B O     1 
HETATM 20040 O O     . HOH N 3 .   ? -0.645   -50.310  -19.919 1.00 24.37  ? 1182 HOH B O     1 
HETATM 20041 O O     . HOH N 3 .   ? -26.761  -38.430  -42.945 1.00 36.15  ? 1183 HOH B O     1 
HETATM 20042 O O     . HOH N 3 .   ? -10.836  -54.846  -38.048 1.00 34.12  ? 1184 HOH B O     1 
HETATM 20043 O O     . HOH N 3 .   ? -8.645   -66.127  -3.220  1.00 32.68  ? 1185 HOH B O     1 
HETATM 20044 O O     . HOH N 3 .   ? -21.890  -55.777  -33.145 1.00 23.14  ? 1186 HOH B O     1 
HETATM 20045 O O     . HOH N 3 .   ? -17.045  -50.769  -46.256 1.00 33.53  ? 1187 HOH B O     1 
HETATM 20046 O O     . HOH N 3 .   ? 4.818    -61.820  -31.101 1.00 39.51  ? 1188 HOH B O     1 
HETATM 20047 O O     . HOH N 3 .   ? -28.032  -53.166  -21.657 1.00 31.96  ? 1189 HOH B O     1 
HETATM 20048 O O     . HOH N 3 .   ? -26.516  -60.970  -23.995 1.00 26.97  ? 1190 HOH B O     1 
HETATM 20049 O O     . HOH N 3 .   ? -14.485  -52.256  -44.659 1.00 32.00  ? 1191 HOH B O     1 
HETATM 20050 O O     . HOH N 3 .   ? -25.794  -55.717  -34.407 1.00 21.42  ? 1192 HOH B O     1 
HETATM 20051 O O     . HOH N 3 .   ? -9.466   -53.051  17.745  1.00 21.97  ? 1193 HOH B O     1 
HETATM 20052 O O     . HOH N 3 .   ? -19.112  -50.809  -31.206 1.00 18.07  ? 1194 HOH B O     1 
HETATM 20053 O O     . HOH N 3 .   ? 1.326    -48.021  -23.665 1.00 43.85  ? 1195 HOH B O     1 
HETATM 20054 O O     . HOH N 3 .   ? -16.142  -64.999  9.247   1.00 24.30  ? 1196 HOH B O     1 
HETATM 20055 O O     . HOH N 3 .   ? -22.963  -59.752  -16.309 1.00 22.95  ? 1197 HOH B O     1 
HETATM 20056 O O     . HOH N 3 .   ? -16.740  -50.554  5.420   1.00 25.03  ? 1198 HOH B O     1 
HETATM 20057 O O     . HOH N 3 .   ? -24.354  -56.096  -47.388 1.00 28.79  ? 1199 HOH B O     1 
HETATM 20058 O O     . HOH N 3 .   ? -29.957  -41.444  -13.147 1.00 31.40  ? 1200 HOH B O     1 
HETATM 20059 O O     . HOH N 3 .   ? -33.676  -56.220  -42.312 1.00 36.60  ? 1201 HOH B O     1 
HETATM 20060 O O     . HOH N 3 .   ? -20.830  -63.860  5.423   1.00 25.76  ? 1202 HOH B O     1 
HETATM 20061 O O     . HOH N 3 .   ? -14.627  -46.869  18.219  1.00 30.82  ? 1203 HOH B O     1 
HETATM 20062 O O     . HOH N 3 .   ? -25.804  -62.615  18.988  1.00 39.25  ? 1204 HOH B O     1 
HETATM 20063 O O     . HOH N 3 .   ? -18.297  -60.975  -2.679  1.00 31.16  ? 1205 HOH B O     1 
HETATM 20064 O O     . HOH N 3 .   ? -13.376  -59.355  -18.280 1.00 41.57  ? 1206 HOH B O     1 
HETATM 20065 O O     . HOH N 3 .   ? -24.507  -62.023  11.076  1.00 28.36  ? 1207 HOH B O     1 
HETATM 20066 O O     . HOH N 3 .   ? -10.442  -66.283  18.505  1.00 33.11  ? 1208 HOH B O     1 
HETATM 20067 O O     . HOH N 3 .   ? -16.718  -54.914  18.118  1.00 18.87  ? 1209 HOH B O     1 
HETATM 20068 O O     . HOH N 3 .   ? -9.497   -37.467  -38.470 1.00 44.68  ? 1210 HOH B O     1 
HETATM 20069 O O     . HOH N 3 .   ? -31.715  -59.700  -12.013 1.00 38.24  ? 1211 HOH B O     1 
HETATM 20070 O O     . HOH N 3 .   ? -31.777  -60.063  -47.446 1.00 33.94  ? 1212 HOH B O     1 
HETATM 20071 O O     . HOH N 3 .   ? -6.729   -62.310  22.165  1.00 37.80  ? 1213 HOH B O     1 
HETATM 20072 O O     . HOH N 3 .   ? 3.641    -48.426  -24.944 1.00 35.67  ? 1214 HOH B O     1 
HETATM 20073 O O     . HOH N 3 .   ? -25.701  -61.316  -19.826 1.00 29.53  ? 1215 HOH B O     1 
HETATM 20074 O O     . HOH N 3 .   ? 0.474    -53.011  -0.903  1.00 39.81  ? 1216 HOH B O     1 
HETATM 20075 O O     . HOH N 3 .   ? -6.460   -56.861  -46.417 1.00 40.86  ? 1217 HOH B O     1 
HETATM 20076 O O     . HOH N 3 .   ? -12.157  -41.019  -7.538  1.00 39.52  ? 1218 HOH B O     1 
HETATM 20077 O O     . HOH N 3 .   ? 4.030    -61.191  -16.281 1.00 27.85  ? 1219 HOH B O     1 
HETATM 20078 O O     . HOH N 3 .   ? -25.912  -43.854  8.845   1.00 27.94  ? 1220 HOH B O     1 
HETATM 20079 O O     . HOH N 3 .   ? -6.268   -70.815  22.551  1.00 37.64  ? 1221 HOH B O     1 
HETATM 20080 O O     . HOH N 3 .   ? -27.590  -47.532  14.706  1.00 23.89  ? 1222 HOH B O     1 
HETATM 20081 O O     . HOH N 3 .   ? -21.044  -61.299  -16.872 1.00 39.49  ? 1223 HOH B O     1 
HETATM 20082 O O     . HOH N 3 .   ? -5.633   -34.859  -22.862 1.00 37.81  ? 1224 HOH B O     1 
HETATM 20083 O O     . HOH N 3 .   ? -11.826  -35.708  -19.073 1.00 39.66  ? 1225 HOH B O     1 
HETATM 20084 O O     . HOH N 3 .   ? -27.180  -56.567  -47.519 1.00 17.22  ? 1226 HOH B O     1 
HETATM 20085 O O     . HOH N 3 .   ? 4.251    -63.903  -29.709 1.00 29.55  ? 1227 HOH B O     1 
HETATM 20086 O O     . HOH N 3 .   ? -14.889  -49.887  -47.185 1.00 31.81  ? 1228 HOH B O     1 
HETATM 20087 O O     . HOH N 3 .   ? -21.288  -44.266  12.358  1.00 49.02  ? 1229 HOH B O     1 
HETATM 20088 O O     . HOH N 3 .   ? -21.694  -34.153  -33.579 1.00 36.01  ? 1230 HOH B O     1 
HETATM 20089 O O     . HOH N 3 .   ? 6.409    -54.334  -17.978 1.00 29.77  ? 1231 HOH B O     1 
HETATM 20090 O O     . HOH N 3 .   ? -5.800   -49.611  -2.495  1.00 29.44  ? 1232 HOH B O     1 
HETATM 20091 O O     . HOH N 3 .   ? 10.157   -67.404  -16.476 1.00 40.08  ? 1233 HOH B O     1 
HETATM 20092 O O     . HOH N 3 .   ? -16.371  -63.332  -2.637  1.00 29.54  ? 1234 HOH B O     1 
HETATM 20093 O O     . HOH N 3 .   ? -3.980   -48.744  2.401   1.00 41.38  ? 1235 HOH B O     1 
HETATM 20094 O O     . HOH N 3 .   ? -31.083  -54.818  8.496   1.00 32.83  ? 1236 HOH B O     1 
HETATM 20095 O O     . HOH N 3 .   ? -10.553  -56.451  21.631  1.00 32.08  ? 1237 HOH B O     1 
HETATM 20096 O O     . HOH N 3 .   ? -27.483  -58.676  4.924   1.00 33.08  ? 1238 HOH B O     1 
HETATM 20097 O O     . HOH N 3 .   ? -35.558  -51.354  -32.479 1.00 33.88  ? 1239 HOH B O     1 
HETATM 20098 O O     . HOH N 3 .   ? -12.973  -69.102  3.409   1.00 45.82  ? 1240 HOH B O     1 
HETATM 20099 O O     . HOH N 3 .   ? -25.444  -61.075  -17.083 1.00 26.21  ? 1241 HOH B O     1 
HETATM 20100 O O     . HOH N 3 .   ? -11.425  -43.954  -43.781 1.00 40.68  ? 1242 HOH B O     1 
HETATM 20101 O O     . HOH N 3 .   ? -8.279   -55.393  -3.961  1.00 37.19  ? 1243 HOH B O     1 
HETATM 20102 O O     . HOH N 3 .   ? -30.758  -45.538  -27.912 1.00 24.44  ? 1244 HOH B O     1 
HETATM 20103 O O     . HOH N 3 .   ? -3.407   -48.381  15.171  1.00 40.66  ? 1245 HOH B O     1 
HETATM 20104 O O     . HOH N 3 .   ? -31.840  -42.652  -20.107 1.00 39.73  ? 1246 HOH B O     1 
HETATM 20105 O O     . HOH N 3 .   ? -6.199   -45.695  -2.792  1.00 41.62  ? 1247 HOH B O     1 
HETATM 20106 O O     . HOH N 3 .   ? -24.006  -57.497  13.545  1.00 24.40  ? 1248 HOH B O     1 
HETATM 20107 O O     . HOH N 3 .   ? 1.694    -67.411  14.738  1.00 44.23  ? 1249 HOH B O     1 
HETATM 20108 O O     . HOH N 3 .   ? -25.864  -63.486  -15.547 1.00 44.31  ? 1250 HOH B O     1 
HETATM 20109 O O     . HOH N 3 .   ? -29.261  -63.467  -21.859 1.00 28.07  ? 1251 HOH B O     1 
HETATM 20110 O O     . HOH N 3 .   ? 3.808    -46.001  -27.439 1.00 36.46  ? 1252 HOH B O     1 
HETATM 20111 O O     . HOH N 3 .   ? -11.757  -42.072  -1.017  1.00 38.47  ? 1253 HOH B O     1 
HETATM 20112 O O     . HOH N 3 .   ? -26.176  -64.762  1.786   1.00 43.71  ? 1254 HOH B O     1 
HETATM 20113 O O     . HOH N 3 .   ? -26.156  -49.411  -19.475 1.00 34.59  ? 1255 HOH B O     1 
HETATM 20114 O O     . HOH N 3 .   ? 5.760    -52.987  -20.562 1.00 32.71  ? 1256 HOH B O     1 
HETATM 20115 O O     . HOH N 3 .   ? 4.389    -57.761  -36.770 1.00 34.27  ? 1257 HOH B O     1 
HETATM 20116 O O     . HOH N 3 .   ? -25.149  -60.176  22.203  1.00 34.69  ? 1258 HOH B O     1 
HETATM 20117 O O     . HOH N 3 .   ? -0.203   -50.901  -17.142 1.00 34.58  ? 1259 HOH B O     1 
HETATM 20118 O O     . HOH N 3 .   ? 7.435    -57.734  -21.608 1.00 27.29  ? 1260 HOH B O     1 
HETATM 20119 O O     . HOH N 3 .   ? -6.926   -62.154  -33.479 1.00 28.71  ? 1261 HOH B O     1 
HETATM 20120 O O     . HOH N 3 .   ? -28.055  -40.642  -11.305 1.00 43.85  ? 1262 HOH B O     1 
HETATM 20121 O O     . HOH N 3 .   ? -4.488   -60.064  -37.361 1.00 41.56  ? 1263 HOH B O     1 
HETATM 20122 O O     . HOH N 3 .   ? 6.693    -63.533  -27.934 1.00 39.18  ? 1264 HOH B O     1 
HETATM 20123 O O     . HOH N 3 .   ? -32.096  -45.565  -18.680 1.00 25.72  ? 1265 HOH B O     1 
HETATM 20124 O O     . HOH N 3 .   ? -23.406  -38.750  -20.882 1.00 36.99  ? 1266 HOH B O     1 
HETATM 20125 O O     . HOH N 3 .   ? 2.823    -43.706  -28.255 1.00 40.05  ? 1267 HOH B O     1 
HETATM 20126 O O     . HOH N 3 .   ? -31.929  -63.735  -14.274 1.00 38.47  ? 1268 HOH B O     1 
HETATM 20127 O O     . HOH N 3 .   ? -21.168  -39.497  -12.348 1.00 44.34  ? 1269 HOH B O     1 
HETATM 20128 O O     . HOH N 3 .   ? -25.100  -40.322  -5.113  1.00 32.39  ? 1270 HOH B O     1 
HETATM 20129 O O     . HOH N 3 .   ? -19.462  -36.376  -15.421 1.00 45.78  ? 1271 HOH B O     1 
HETATM 20130 O O     . HOH N 3 .   ? -18.664  -48.568  19.592  1.00 30.95  ? 1272 HOH B O     1 
HETATM 20131 O O     . HOH N 3 .   ? -5.995   -39.983  -37.466 1.00 38.22  ? 1273 HOH B O     1 
HETATM 20132 O O     . HOH N 3 .   ? -0.218   -47.175  7.108   1.00 42.72  ? 1274 HOH B O     1 
HETATM 20133 O O     . HOH N 3 .   ? -29.097  -61.806  -24.014 1.00 31.70  ? 1275 HOH B O     1 
HETATM 20134 O O     . HOH N 3 .   ? -26.327  -42.645  -5.021  1.00 28.88  ? 1276 HOH B O     1 
HETATM 20135 O O     . HOH N 3 .   ? -3.730   -60.865  -8.023  1.00 27.74  ? 1277 HOH B O     1 
HETATM 20136 O O     . HOH N 3 .   ? -1.563   -62.411  6.053   1.00 46.52  ? 1278 HOH B O     1 
HETATM 20137 O O     . HOH N 3 .   ? -8.292   -41.241  -45.399 1.00 57.39  ? 1279 HOH B O     1 
HETATM 20138 O O     . HOH N 3 .   ? -9.189   -71.453  19.217  1.00 37.38  ? 1280 HOH B O     1 
HETATM 20139 O O     . HOH N 3 .   ? -28.161  -41.727  -8.326  1.00 46.62  ? 1281 HOH B O     1 
HETATM 20140 O O     . HOH N 3 .   ? 0.116    -56.623  6.538   1.00 51.86  ? 1282 HOH B O     1 
HETATM 20141 O O     . HOH N 3 .   ? -5.512   -58.775  -8.128  1.00 30.65  ? 1283 HOH B O     1 
HETATM 20142 O O     . HOH N 3 .   ? -30.285  -42.735  -31.183 1.00 34.50  ? 1284 HOH B O     1 
HETATM 20143 O O     . HOH N 3 .   ? -3.175   -70.922  8.928   1.00 36.30  ? 1285 HOH B O     1 
HETATM 20144 O O     . HOH N 3 .   ? -25.637  -62.989  14.137  1.00 45.63  ? 1286 HOH B O     1 
HETATM 20145 O O     . HOH N 3 .   ? -29.775  -61.430  -13.225 1.00 23.64  ? 1287 HOH B O     1 
HETATM 20146 O O     . HOH N 3 .   ? -13.137  -43.091  -5.647  1.00 37.15  ? 1288 HOH B O     1 
HETATM 20147 O O     . HOH N 3 .   ? -25.064  -48.194  15.347  1.00 28.07  ? 1289 HOH B O     1 
HETATM 20148 O O     . HOH N 3 .   ? -5.816   -80.262  16.064  1.00 38.72  ? 1290 HOH B O     1 
HETATM 20149 O O     . HOH N 3 .   ? -4.224   -47.160  -3.439  1.00 37.25  ? 1291 HOH B O     1 
HETATM 20150 O O     . HOH N 3 .   ? 5.625    -54.201  -37.200 1.00 48.22  ? 1292 HOH B O     1 
HETATM 20151 O O     . HOH N 3 .   ? -31.807  -47.391  -20.444 1.00 37.77  ? 1293 HOH B O     1 
HETATM 20152 O O     . HOH N 3 .   ? 2.464    -62.472  -7.266  1.00 34.91  ? 1294 HOH B O     1 
HETATM 20153 O O     . HOH N 3 .   ? -32.651  -45.453  -25.832 1.00 41.71  ? 1295 HOH B O     1 
HETATM 20154 O O     . HOH O 3 .   ? 9.492    -107.480 -8.483  1.00 40.87  ? 1101 HOH C O     1 
HETATM 20155 O O     . HOH O 3 .   ? -51.028  -88.923  -28.851 1.00 37.95  ? 1102 HOH C O     1 
HETATM 20156 O O     . HOH O 3 .   ? -26.076  -118.610 -3.613  1.00 46.79  ? 1103 HOH C O     1 
HETATM 20157 O O     . HOH O 3 .   ? -28.425  -107.585 -17.413 1.00 47.57  ? 1104 HOH C O     1 
HETATM 20158 O O     . HOH O 3 .   ? -51.057  -95.134  -8.395  1.00 24.90  ? 1105 HOH C O     1 
HETATM 20159 O O     . HOH O 3 .   ? -18.912  -110.626 12.023  1.00 37.49  ? 1106 HOH C O     1 
HETATM 20160 O O     . HOH O 3 .   ? 0.450    -103.111 5.262   1.00 32.61  ? 1107 HOH C O     1 
HETATM 20161 O O     . HOH O 3 .   ? -18.565  -92.648  -8.127  1.00 35.14  ? 1108 HOH C O     1 
HETATM 20162 O O     . HOH O 3 .   ? -14.937  -104.233 5.810   1.00 16.03  ? 1109 HOH C O     1 
HETATM 20163 O O     . HOH O 3 .   ? 15.968   -98.170  -2.856  1.00 24.48  ? 1110 HOH C O     1 
HETATM 20164 O O     . HOH O 3 .   ? -5.302   -89.633  11.677  1.00 31.86  ? 1111 HOH C O     1 
HETATM 20165 O O     . HOH O 3 .   ? -55.271  -87.404  -11.188 1.00 28.98  ? 1112 HOH C O     1 
HETATM 20166 O O     . HOH O 3 .   ? -0.826   -96.651  -21.421 1.00 47.68  ? 1113 HOH C O     1 
HETATM 20167 O O     . HOH O 3 .   ? -41.100  -89.966  -5.292  1.00 33.04  ? 1114 HOH C O     1 
HETATM 20168 O O     . HOH O 3 .   ? -34.115  -87.796  -19.931 1.00 17.72  ? 1115 HOH C O     1 
HETATM 20169 O O     . HOH O 3 .   ? -43.234  -89.166  -1.047  1.00 38.28  ? 1116 HOH C O     1 
HETATM 20170 O O     . HOH O 3 .   ? -47.404  -77.172  -31.977 1.00 35.40  ? 1117 HOH C O     1 
HETATM 20171 O O     . HOH O 3 .   ? -32.063  -88.322  1.322   1.00 42.71  ? 1118 HOH C O     1 
HETATM 20172 O O     . HOH O 3 .   ? -17.361  -119.180 1.246   1.00 44.34  ? 1119 HOH C O     1 
HETATM 20173 O O     . HOH O 3 .   ? -29.028  -89.290  2.373   1.00 23.72  ? 1120 HOH C O     1 
HETATM 20174 O O     . HOH O 3 .   ? -11.400  -113.276 9.414   1.00 32.72  ? 1121 HOH C O     1 
HETATM 20175 O O     . HOH O 3 .   ? 4.667    -109.335 -0.276  1.00 33.49  ? 1122 HOH C O     1 
HETATM 20176 O O     . HOH O 3 .   ? -13.759  -109.371 -25.453 1.00 29.46  ? 1123 HOH C O     1 
HETATM 20177 O O     . HOH O 3 .   ? 2.746    -117.677 -1.415  1.00 38.74  ? 1124 HOH C O     1 
HETATM 20178 O O     . HOH O 3 .   ? -30.954  -101.405 -24.841 1.00 30.08  ? 1125 HOH C O     1 
HETATM 20179 O O     . HOH O 3 .   ? -23.325  -112.113 -17.326 1.00 46.91  ? 1126 HOH C O     1 
HETATM 20180 O O     . HOH O 3 .   ? -6.238   -106.312 1.535   1.00 23.96  ? 1127 HOH C O     1 
HETATM 20181 O O     . HOH O 3 .   ? -26.092  -108.883 -22.010 1.00 41.62  ? 1128 HOH C O     1 
HETATM 20182 O O     . HOH O 3 .   ? 1.536    -106.573 -1.062  1.00 31.95  ? 1129 HOH C O     1 
HETATM 20183 O O     . HOH O 3 .   ? -24.178  -93.331  -22.252 1.00 47.09  ? 1130 HOH C O     1 
HETATM 20184 O O     . HOH O 3 .   ? -52.108  -86.720  -9.822  1.00 32.92  ? 1131 HOH C O     1 
HETATM 20185 O O     . HOH O 3 .   ? -40.817  -90.247  -2.832  1.00 30.90  ? 1132 HOH C O     1 
HETATM 20186 O O     . HOH O 3 .   ? -49.547  -93.227  7.665   1.00 22.20  ? 1133 HOH C O     1 
HETATM 20187 O O     . HOH O 3 .   ? -46.567  -101.348 1.148   1.00 22.80  ? 1134 HOH C O     1 
HETATM 20188 O O     . HOH O 3 .   ? -13.386  -121.815 -7.550  1.00 40.49  ? 1135 HOH C O     1 
HETATM 20189 O O     . HOH O 3 .   ? -52.091  -94.292  -21.022 1.00 24.21  ? 1136 HOH C O     1 
HETATM 20190 O O     . HOH O 3 .   ? -21.474  -97.056  -19.509 1.00 24.10  ? 1137 HOH C O     1 
HETATM 20191 O O     . HOH O 3 .   ? -52.248  -93.409  -6.874  1.00 33.29  ? 1138 HOH C O     1 
HETATM 20192 O O     . HOH O 3 .   ? -52.527  -88.601  -7.676  1.00 20.74  ? 1139 HOH C O     1 
HETATM 20193 O O     . HOH O 3 .   ? -53.990  -92.532  -13.869 1.00 19.54  ? 1140 HOH C O     1 
HETATM 20194 O O     . HOH O 3 .   ? -47.061  -86.323  -6.141  1.00 24.55  ? 1141 HOH C O     1 
HETATM 20195 O O     . HOH O 3 .   ? 3.310    -103.689 -15.994 1.00 30.81  ? 1142 HOH C O     1 
HETATM 20196 O O     . HOH O 3 .   ? -43.916  -99.481  -27.480 1.00 36.38  ? 1143 HOH C O     1 
HETATM 20197 O O     . HOH O 3 .   ? 8.085    -107.153 -1.020  1.00 37.08  ? 1144 HOH C O     1 
HETATM 20198 O O     . HOH O 3 .   ? -44.938  -86.428  -27.485 1.00 27.56  ? 1145 HOH C O     1 
HETATM 20199 O O     . HOH O 3 .   ? -21.392  -99.347  2.710   1.00 40.78  ? 1146 HOH C O     1 
HETATM 20200 O O     . HOH O 3 .   ? -37.977  -81.513  -8.289  1.00 36.97  ? 1147 HOH C O     1 
HETATM 20201 O O     . HOH O 3 .   ? -8.222   -117.120 -13.660 1.00 28.98  ? 1148 HOH C O     1 
HETATM 20202 O O     . HOH O 3 .   ? -10.584  -100.506 10.161  1.00 17.38  ? 1149 HOH C O     1 
HETATM 20203 O O     . HOH O 3 .   ? 1.566    -97.131  -19.163 1.00 42.01  ? 1150 HOH C O     1 
HETATM 20204 O O     . HOH O 3 .   ? -7.094   -105.670 -27.561 1.00 37.62  ? 1151 HOH C O     1 
HETATM 20205 O O     . HOH O 3 .   ? -40.491  -76.551  -19.067 1.00 34.35  ? 1152 HOH C O     1 
HETATM 20206 O O     . HOH O 3 .   ? -46.816  -80.956  -11.981 1.00 28.37  ? 1153 HOH C O     1 
HETATM 20207 O O     . HOH O 3 .   ? -12.576  -115.511 14.180  1.00 38.61  ? 1154 HOH C O     1 
HETATM 20208 O O     . HOH O 3 .   ? -38.075  -103.143 -23.045 1.00 44.24  ? 1155 HOH C O     1 
HETATM 20209 O O     . HOH O 3 .   ? -3.953   -100.372 -13.502 1.00 26.65  ? 1156 HOH C O     1 
HETATM 20210 O O     . HOH O 3 .   ? 0.496    -118.683 -0.756  1.00 39.38  ? 1157 HOH C O     1 
HETATM 20211 O O     . HOH O 3 .   ? -18.682  -98.466  6.285   1.00 24.26  ? 1158 HOH C O     1 
HETATM 20212 O O     . HOH O 3 .   ? 1.026    -100.612 17.967  1.00 38.38  ? 1159 HOH C O     1 
HETATM 20213 O O     . HOH O 3 .   ? -20.223  -96.715  20.035  1.00 28.36  ? 1160 HOH C O     1 
HETATM 20214 O O     . HOH O 3 .   ? -10.647  -100.655 16.553  1.00 30.50  ? 1161 HOH C O     1 
HETATM 20215 O O     . HOH O 3 .   ? -45.435  -79.421  -17.600 1.00 37.28  ? 1162 HOH C O     1 
HETATM 20216 O O     . HOH O 3 .   ? -42.654  -78.263  -14.414 1.00 28.44  ? 1163 HOH C O     1 
HETATM 20217 O O     . HOH O 3 .   ? -11.343  -92.256  -13.522 1.00 47.78  ? 1164 HOH C O     1 
HETATM 20218 O O     . HOH O 3 .   ? -38.824  -84.118  -10.347 1.00 27.05  ? 1165 HOH C O     1 
HETATM 20219 O O     . HOH O 3 .   ? -38.662  -71.862  -11.245 1.00 38.40  ? 1166 HOH C O     1 
HETATM 20220 O O     . HOH O 3 .   ? -15.816  -100.516 -27.140 1.00 35.91  ? 1167 HOH C O     1 
HETATM 20221 O O     . HOH O 3 .   ? -22.625  -90.603  4.038   1.00 25.91  ? 1168 HOH C O     1 
HETATM 20222 O O     . HOH O 3 .   ? -10.077  -109.122 8.788   1.00 35.58  ? 1169 HOH C O     1 
HETATM 20223 O O     . HOH O 3 .   ? -49.890  -99.397  -1.128  1.00 35.48  ? 1170 HOH C O     1 
HETATM 20224 O O     . HOH O 3 .   ? 2.086    -95.153  -17.349 1.00 32.62  ? 1171 HOH C O     1 
HETATM 20225 O O     . HOH O 3 .   ? -38.685  -80.131  -29.565 1.00 33.44  ? 1172 HOH C O     1 
HETATM 20226 O O     . HOH O 3 .   ? -41.951  -104.444 -12.869 1.00 25.00  ? 1173 HOH C O     1 
HETATM 20227 O O     . HOH O 3 .   ? -16.298  -109.897 -18.965 1.00 29.15  ? 1174 HOH C O     1 
HETATM 20228 O O     . HOH O 3 .   ? -17.325  -91.389  1.581   1.00 34.31  ? 1175 HOH C O     1 
HETATM 20229 O O     . HOH O 3 .   ? -47.311  -99.194  -5.524  1.00 26.64  ? 1176 HOH C O     1 
HETATM 20230 O O     . HOH O 3 .   ? -45.971  -94.686  -32.497 1.00 47.38  ? 1177 HOH C O     1 
HETATM 20231 O O     . HOH O 3 .   ? -31.804  -89.967  -20.151 1.00 40.96  ? 1178 HOH C O     1 
HETATM 20232 O O     . HOH O 3 .   ? -35.191  -77.351  -14.297 1.00 47.00  ? 1179 HOH C O     1 
HETATM 20233 O O     . HOH O 3 .   ? -40.658  -105.029 -5.764  1.00 28.55  ? 1180 HOH C O     1 
HETATM 20234 O O     . HOH O 3 .   ? -3.669   -119.081 -6.934  1.00 30.77  ? 1181 HOH C O     1 
HETATM 20235 O O     . HOH O 3 .   ? 6.999    -99.036  -0.279  1.00 34.36  ? 1182 HOH C O     1 
HETATM 20236 O O     . HOH O 3 .   ? -9.542   -103.535 -25.981 1.00 36.42  ? 1183 HOH C O     1 
HETATM 20237 O O     . HOH O 3 .   ? -22.337  -99.343  13.135  1.00 26.93  ? 1184 HOH C O     1 
HETATM 20238 O O     . HOH O 3 .   ? -9.423   -97.206  -23.525 1.00 37.71  ? 1185 HOH C O     1 
HETATM 20239 O O     . HOH O 3 .   ? -23.476  -98.495  -18.337 1.00 25.20  ? 1186 HOH C O     1 
HETATM 20240 O O     . HOH O 3 .   ? -9.014   -105.850 0.899   1.00 21.57  ? 1187 HOH C O     1 
HETATM 20241 O O     . HOH O 3 .   ? -35.709  -80.415  -15.930 1.00 38.10  ? 1188 HOH C O     1 
HETATM 20242 O O     . HOH O 3 .   ? -41.124  -83.546  -15.916 1.00 23.86  ? 1189 HOH C O     1 
HETATM 20243 O O     . HOH O 3 .   ? -12.573  -101.314 7.949   1.00 18.62  ? 1190 HOH C O     1 
HETATM 20244 O O     . HOH O 3 .   ? -25.874  -88.996  5.533   1.00 32.02  ? 1191 HOH C O     1 
HETATM 20245 O O     . HOH O 3 .   ? -1.385   -104.058 -24.297 1.00 46.52  ? 1192 HOH C O     1 
HETATM 20246 O O     . HOH O 3 .   ? -13.228  -113.475 -19.125 1.00 40.35  ? 1193 HOH C O     1 
HETATM 20247 O O     . HOH O 3 .   ? -19.535  -99.528  8.419   1.00 27.68  ? 1194 HOH C O     1 
HETATM 20248 O O     . HOH O 3 .   ? -24.667  -85.840  7.792   1.00 31.59  ? 1195 HOH C O     1 
HETATM 20249 O O     . HOH O 3 .   ? -30.782  -88.360  -12.317 1.00 30.22  ? 1196 HOH C O     1 
HETATM 20250 O O     . HOH O 3 .   ? -42.728  -97.469  -10.395 1.00 21.45  ? 1197 HOH C O     1 
HETATM 20251 O O     . HOH O 3 .   ? -21.583  -98.282  10.693  1.00 29.07  ? 1198 HOH C O     1 
HETATM 20252 O O     . HOH O 3 .   ? -20.379  -113.934 4.309   1.00 35.05  ? 1199 HOH C O     1 
HETATM 20253 O O     . HOH O 3 .   ? -31.931  -89.831  -9.895  1.00 28.64  ? 1200 HOH C O     1 
HETATM 20254 O O     . HOH O 3 .   ? 0.982    -101.196 -13.446 1.00 33.41  ? 1201 HOH C O     1 
HETATM 20255 O O     . HOH O 3 .   ? -13.577  -92.206  3.459   1.00 23.28  ? 1202 HOH C O     1 
HETATM 20256 O O     . HOH O 3 .   ? -28.133  -96.492  -18.850 1.00 20.14  ? 1203 HOH C O     1 
HETATM 20257 O O     . HOH O 3 .   ? -37.806  -88.601  -5.535  1.00 22.13  ? 1204 HOH C O     1 
HETATM 20258 O O     . HOH O 3 .   ? -22.885  -112.672 5.695   1.00 38.43  ? 1205 HOH C O     1 
HETATM 20259 O O     . HOH O 3 .   ? -43.757  -71.512  -31.736 1.00 33.83  ? 1206 HOH C O     1 
HETATM 20260 O O     . HOH O 3 .   ? -4.021   -110.278 15.592  1.00 51.12  ? 1207 HOH C O     1 
HETATM 20261 O O     . HOH O 3 .   ? -54.000  -93.916  -1.936  1.00 25.02  ? 1208 HOH C O     1 
HETATM 20262 O O     . HOH O 3 .   ? -54.352  -92.687  -8.915  1.00 26.68  ? 1209 HOH C O     1 
HETATM 20263 O O     . HOH O 3 .   ? -24.547  -111.520 -14.797 1.00 33.91  ? 1210 HOH C O     1 
HETATM 20264 O O     . HOH O 3 .   ? -33.824  -103.923 -18.434 1.00 27.38  ? 1211 HOH C O     1 
HETATM 20265 O O     . HOH O 3 .   ? -5.411   -100.192 6.644   1.00 20.05  ? 1212 HOH C O     1 
HETATM 20266 O O     . HOH O 3 .   ? -6.143   -101.040 2.870   1.00 24.13  ? 1213 HOH C O     1 
HETATM 20267 O O     . HOH O 3 .   ? -18.843  -92.342  -3.929  1.00 38.01  ? 1214 HOH C O     1 
HETATM 20268 O O     . HOH O 3 .   ? -17.269  -96.860  -10.017 1.00 32.32  ? 1215 HOH C O     1 
HETATM 20269 O O     . HOH O 3 .   ? -6.381   -121.797 -4.968  1.00 38.60  ? 1216 HOH C O     1 
HETATM 20270 O O     . HOH O 3 .   ? 4.079    -97.708  0.333   1.00 40.99  ? 1217 HOH C O     1 
HETATM 20271 O O     . HOH O 3 .   ? 0.128    -106.690 -5.729  1.00 28.17  ? 1218 HOH C O     1 
HETATM 20272 O O     . HOH O 3 .   ? -45.493  -83.094  -7.830  1.00 33.82  ? 1219 HOH C O     1 
HETATM 20273 O O     . HOH O 3 .   ? -15.569  -106.147 12.231  1.00 31.58  ? 1220 HOH C O     1 
HETATM 20274 O O     . HOH O 3 .   ? -11.341  -114.073 -21.073 1.00 44.06  ? 1221 HOH C O     1 
HETATM 20275 O O     . HOH O 3 .   ? 15.704   -103.343 -9.527  1.00 47.08  ? 1222 HOH C O     1 
HETATM 20276 O O     . HOH O 3 .   ? -36.161  -107.222 -0.446  1.00 35.85  ? 1223 HOH C O     1 
HETATM 20277 O O     . HOH O 3 .   ? 2.654    -108.222 -21.405 1.00 39.66  ? 1224 HOH C O     1 
HETATM 20278 O O     . HOH O 3 .   ? -19.754  -91.198  0.400   1.00 28.15  ? 1225 HOH C O     1 
HETATM 20279 O O     . HOH O 3 .   ? -49.238  -86.575  -7.771  1.00 22.74  ? 1226 HOH C O     1 
HETATM 20280 O O     . HOH O 3 .   ? -1.445   -100.027 -12.659 1.00 23.83  ? 1227 HOH C O     1 
HETATM 20281 O O     . HOH O 3 .   ? -15.250  -88.622  4.864   1.00 29.79  ? 1228 HOH C O     1 
HETATM 20282 O O     . HOH O 3 .   ? -34.038  -106.737 -10.882 1.00 46.42  ? 1229 HOH C O     1 
HETATM 20283 O O     . HOH O 3 .   ? -20.340  -92.775  -1.647  1.00 20.27  ? 1230 HOH C O     1 
HETATM 20284 O O     . HOH O 3 .   ? -50.236  -83.767  -6.941  1.00 30.75  ? 1231 HOH C O     1 
HETATM 20285 O O     . HOH O 3 .   ? -55.504  -98.038  -14.471 1.00 29.59  ? 1232 HOH C O     1 
HETATM 20286 O O     . HOH O 3 .   ? -18.337  -121.195 -3.040  1.00 46.05  ? 1233 HOH C O     1 
HETATM 20287 O O     . HOH O 3 .   ? -15.659  -108.223 -26.761 1.00 35.60  ? 1234 HOH C O     1 
HETATM 20288 O O     . HOH O 3 .   ? -18.709  -108.628 -20.220 1.00 35.88  ? 1235 HOH C O     1 
HETATM 20289 O O     . HOH O 3 .   ? -49.989  -83.422  -31.939 1.00 33.75  ? 1236 HOH C O     1 
HETATM 20290 O O     . HOH O 3 .   ? -56.355  -81.457  -9.550  1.00 32.81  ? 1237 HOH C O     1 
HETATM 20291 O O     . HOH O 3 .   ? -46.485  -87.819  0.775   1.00 31.86  ? 1238 HOH C O     1 
HETATM 20292 O O     . HOH O 3 .   ? -34.893  -107.554 -16.844 1.00 38.78  ? 1239 HOH C O     1 
HETATM 20293 O O     . HOH O 3 .   ? -39.188  -89.557  -31.069 1.00 39.47  ? 1240 HOH C O     1 
HETATM 20294 O O     . HOH O 3 .   ? -24.670  -103.458 11.267  1.00 34.69  ? 1241 HOH C O     1 
HETATM 20295 O O     . HOH O 3 .   ? -18.314  -90.167  -6.186  1.00 42.05  ? 1242 HOH C O     1 
HETATM 20296 O O     . HOH O 3 .   ? -10.233  -106.618 -27.182 1.00 37.30  ? 1243 HOH C O     1 
HETATM 20297 O O     . HOH O 3 .   ? -15.929  -110.092 12.903  1.00 43.17  ? 1244 HOH C O     1 
HETATM 20298 O O     . HOH O 3 .   ? -33.996  -82.341  -18.527 1.00 41.75  ? 1245 HOH C O     1 
HETATM 20299 O O     . HOH O 3 .   ? -7.645   -119.965 -15.454 1.00 38.65  ? 1246 HOH C O     1 
HETATM 20300 O O     . HOH O 3 .   ? -34.408  -107.544 -7.226  1.00 40.84  ? 1247 HOH C O     1 
HETATM 20301 O O     . HOH O 3 .   ? -9.760   -116.878 -19.846 1.00 38.25  ? 1248 HOH C O     1 
HETATM 20302 O O     . HOH O 3 .   ? -30.853  -106.411 9.023   1.00 40.89  ? 1249 HOH C O     1 
HETATM 20303 O O     . HOH O 3 .   ? 11.875   -106.024 -12.229 1.00 32.24  ? 1250 HOH C O     1 
HETATM 20304 O O     . HOH O 3 .   ? -54.956  -89.974  -21.968 1.00 29.94  ? 1251 HOH C O     1 
HETATM 20305 O O     . HOH O 3 .   ? -13.791  -90.932  5.707   1.00 22.32  ? 1252 HOH C O     1 
HETATM 20306 O O     . HOH O 3 .   ? -21.572  -101.835 4.816   1.00 39.39  ? 1253 HOH C O     1 
HETATM 20307 O O     . HOH O 3 .   ? -33.023  -102.841 -25.663 1.00 32.85  ? 1254 HOH C O     1 
HETATM 20308 O O     . HOH O 3 .   ? 2.319    -103.511 -13.463 1.00 33.86  ? 1255 HOH C O     1 
HETATM 20309 O O     . HOH O 3 .   ? -24.534  -96.344  -22.078 1.00 32.26  ? 1256 HOH C O     1 
HETATM 20310 O O     . HOH O 3 .   ? -19.061  -110.878 -22.100 1.00 35.67  ? 1257 HOH C O     1 
HETATM 20311 O O     . HOH O 3 .   ? -23.808  -106.258 12.211  1.00 37.02  ? 1258 HOH C O     1 
HETATM 20312 O O     . HOH O 3 .   ? 0.521    -119.007 -11.808 1.00 40.54  ? 1259 HOH C O     1 
HETATM 20313 O O     . HOH O 3 .   ? -31.189  -98.993  -25.850 1.00 38.38  ? 1260 HOH C O     1 
HETATM 20314 O O     . HOH O 3 .   ? -37.255  -104.320 3.232   1.00 35.12  ? 1261 HOH C O     1 
HETATM 20315 O O     . HOH O 3 .   ? -22.016  -109.909 -24.673 1.00 45.07  ? 1262 HOH C O     1 
HETATM 20316 O O     . HOH O 3 .   ? -33.050  -85.828  -2.735  1.00 46.88  ? 1263 HOH C O     1 
HETATM 20317 O O     . HOH O 3 .   ? -47.287  -77.450  -26.651 1.00 33.42  ? 1264 HOH C O     1 
HETATM 20318 O O     . HOH O 3 .   ? 9.168    -102.721 -15.099 1.00 45.10  ? 1265 HOH C O     1 
HETATM 20319 O O     . HOH O 3 .   ? 7.644    -109.917 -8.269  1.00 42.44  ? 1266 HOH C O     1 
HETATM 20320 O O     . HOH O 3 .   ? -35.294  -71.641  -11.969 1.00 47.87  ? 1267 HOH C O     1 
HETATM 20321 O O     . HOH O 3 .   ? -25.682  -97.481  -19.816 1.00 24.99  ? 1268 HOH C O     1 
HETATM 20322 O O     . HOH O 3 .   ? -37.041  -82.440  -29.375 1.00 42.28  ? 1269 HOH C O     1 
HETATM 20323 O O     . HOH O 3 .   ? -12.969  -109.845 13.501  1.00 36.08  ? 1270 HOH C O     1 
HETATM 20324 O O     . HOH O 3 .   ? -41.121  -71.724  -31.362 1.00 37.01  ? 1271 HOH C O     1 
HETATM 20325 O O     . HOH O 3 .   ? 11.663   -107.586 -10.240 1.00 35.18  ? 1272 HOH C O     1 
HETATM 20326 O O     . HOH O 3 .   ? -24.115  -88.356  3.513   1.00 30.54  ? 1273 HOH C O     1 
HETATM 20327 O O     . HOH O 3 .   ? -33.841  -106.827 -19.153 1.00 37.99  ? 1274 HOH C O     1 
HETATM 20328 O O     . HOH O 3 .   ? -4.022   -121.733 -6.580  1.00 39.12  ? 1275 HOH C O     1 
HETATM 20329 O O     . HOH O 3 .   ? -40.289  -97.576  -30.206 1.00 51.38  ? 1276 HOH C O     1 
HETATM 20330 O O     . HOH O 3 .   ? 7.017    -104.509 -16.260 1.00 46.15  ? 1277 HOH C O     1 
HETATM 20331 O O     . HOH O 3 .   ? -28.149  -87.957  -7.819  1.00 41.17  ? 1278 HOH C O     1 
HETATM 20332 O O     . HOH O 3 .   ? -54.108  -94.012  -4.742  1.00 31.54  ? 1279 HOH C O     1 
HETATM 20333 O O     . HOH O 3 .   ? -0.185   -93.932  -16.651 1.00 39.25  ? 1280 HOH C O     1 
HETATM 20334 O O     . HOH O 3 .   ? -21.708  -109.795 12.423  1.00 47.89  ? 1281 HOH C O     1 
HETATM 20335 O O     . HOH O 3 .   ? -30.024  -97.196  -27.120 1.00 37.32  ? 1282 HOH C O     1 
HETATM 20336 O O     . HOH O 3 .   ? -15.844  -123.500 -3.174  1.00 39.08  ? 1283 HOH C O     1 
HETATM 20337 O O     . HOH O 3 .   ? 1.984    -96.943  5.594   1.00 40.27  ? 1284 HOH C O     1 
HETATM 20338 O O     . HOH O 3 .   ? -54.755  -90.438  -7.931  1.00 39.43  ? 1285 HOH C O     1 
HETATM 20339 O O     . HOH O 3 .   ? -17.487  -124.979 -5.326  1.00 41.38  ? 1286 HOH C O     1 
HETATM 20340 O O     . HOH P 3 .   ? -11.124  -85.819  17.427  1.00 26.79  ? 1101 HOH D O     1 
HETATM 20341 O O     . HOH P 3 .   ? -21.045  -83.606  11.955  1.00 29.24  ? 1102 HOH D O     1 
HETATM 20342 O O     . HOH P 3 .   ? -45.622  -77.069  25.370  1.00 36.12  ? 1103 HOH D O     1 
HETATM 20343 O O     . HOH P 3 .   ? -33.851  -73.406  22.245  1.00 27.57  ? 1104 HOH D O     1 
HETATM 20344 O O     . HOH P 3 .   ? -64.471  -90.811  8.914   1.00 40.01  ? 1105 HOH D O     1 
HETATM 20345 O O     . HOH P 3 .   ? -58.046  -86.287  24.597  1.00 24.86  ? 1106 HOH D O     1 
HETATM 20346 O O     . HOH P 3 .   ? -75.390  -96.351  12.870  1.00 24.08  ? 1107 HOH D O     1 
HETATM 20347 O O     . HOH P 3 .   ? -71.713  -95.203  25.108  1.00 26.56  ? 1108 HOH D O     1 
HETATM 20348 O O     . HOH P 3 .   ? -33.197  -88.170  5.185   1.00 21.30  ? 1109 HOH D O     1 
HETATM 20349 O O     . HOH P 3 .   ? -78.223  -91.895  15.381  1.00 22.40  ? 1110 HOH D O     1 
HETATM 20350 O O     . HOH P 3 .   ? -51.348  -111.837 12.432  1.00 40.49  ? 1111 HOH D O     1 
HETATM 20351 O O     . HOH P 3 .   ? -40.646  -96.216  11.586  1.00 26.15  ? 1112 HOH D O     1 
HETATM 20352 O O     . HOH P 3 .   ? -24.014  -82.546  33.842  1.00 40.05  ? 1113 HOH D O     1 
HETATM 20353 O O     . HOH P 3 .   ? -23.182  -60.744  24.231  1.00 29.70  ? 1114 HOH D O     1 
HETATM 20354 O O     . HOH P 3 .   ? -39.918  -100.288 37.087  1.00 41.49  ? 1115 HOH D O     1 
HETATM 20355 O O     . HOH P 3 .   ? -49.650  -116.068 13.278  1.00 34.84  ? 1116 HOH D O     1 
HETATM 20356 O O     . HOH P 3 .   ? -26.329  -69.833  14.050  1.00 35.37  ? 1117 HOH D O     1 
HETATM 20357 O O     . HOH P 3 .   ? -14.685  -56.987  24.314  1.00 35.48  ? 1118 HOH D O     1 
HETATM 20358 O O     . HOH P 3 .   ? -35.963  -87.443  36.612  1.00 32.44  ? 1119 HOH D O     1 
HETATM 20359 O O     . HOH P 3 .   ? -65.197  -109.876 17.878  1.00 44.82  ? 1120 HOH D O     1 
HETATM 20360 O O     . HOH P 3 .   ? -37.573  -80.349  33.668  1.00 38.46  ? 1121 HOH D O     1 
HETATM 20361 O O     . HOH P 3 .   ? -54.807  -82.149  38.684  1.00 44.75  ? 1122 HOH D O     1 
HETATM 20362 O O     . HOH P 3 .   ? -48.104  -85.927  39.739  1.00 26.27  ? 1123 HOH D O     1 
HETATM 20363 O O     . HOH P 3 .   ? -30.049  -73.979  23.638  1.00 40.47  ? 1124 HOH D O     1 
HETATM 20364 O O     . HOH P 3 .   ? -51.546  -101.617 6.531   1.00 18.91  ? 1125 HOH D O     1 
HETATM 20365 O O     . HOH P 3 .   ? -29.426  -86.794  5.766   1.00 34.95  ? 1126 HOH D O     1 
HETATM 20366 O O     . HOH P 3 .   ? -15.488  -96.760  13.944  1.00 25.61  ? 1127 HOH D O     1 
HETATM 20367 O O     . HOH P 3 .   ? -62.712  -100.770 11.913  1.00 26.43  ? 1128 HOH D O     1 
HETATM 20368 O O     . HOH P 3 .   ? -52.580  -77.889  30.447  1.00 34.63  ? 1129 HOH D O     1 
HETATM 20369 O O     . HOH P 3 .   ? -9.456   -81.007  12.634  1.00 26.91  ? 1130 HOH D O     1 
HETATM 20370 O O     . HOH P 3 .   ? -36.148  -105.972 36.441  1.00 24.47  ? 1131 HOH D O     1 
HETATM 20371 O O     . HOH P 3 .   ? -63.667  -99.136  18.886  1.00 22.60  ? 1132 HOH D O     1 
HETATM 20372 O O     . HOH P 3 .   ? -31.350  -80.358  34.084  1.00 30.99  ? 1133 HOH D O     1 
HETATM 20373 O O     . HOH P 3 .   ? -44.858  -110.423 25.560  1.00 27.06  ? 1134 HOH D O     1 
HETATM 20374 O O     . HOH P 3 .   ? -53.146  -100.101 17.026  1.00 18.89  ? 1135 HOH D O     1 
HETATM 20375 O O     . HOH P 3 .   ? -66.072  -79.563  27.973  1.00 34.45  ? 1136 HOH D O     1 
HETATM 20376 O O     . HOH P 3 .   ? -7.840   -83.568  16.280  1.00 33.57  ? 1137 HOH D O     1 
HETATM 20377 O O     . HOH P 3 .   ? -27.851  -72.862  21.556  1.00 22.64  ? 1138 HOH D O     1 
HETATM 20378 O O     . HOH P 3 .   ? -12.517  -94.829  3.806   1.00 22.42  ? 1139 HOH D O     1 
HETATM 20379 O O     . HOH P 3 .   ? -63.226  -78.830  20.290  1.00 37.01  ? 1140 HOH D O     1 
HETATM 20380 O O     . HOH P 3 .   ? -16.730  -76.803  9.441   1.00 29.56  ? 1141 HOH D O     1 
HETATM 20381 O O     . HOH P 3 .   ? -41.985  -108.449 19.471  1.00 22.65  ? 1142 HOH D O     1 
HETATM 20382 O O     . HOH P 3 .   ? -40.691  -80.124  27.186  1.00 21.69  ? 1143 HOH D O     1 
HETATM 20383 O O     . HOH P 3 .   ? -9.774   -77.188  26.645  1.00 24.63  ? 1144 HOH D O     1 
HETATM 20384 O O     . HOH P 3 .   ? -60.928  -82.154  35.054  1.00 28.40  ? 1145 HOH D O     1 
HETATM 20385 O O     . HOH P 3 .   ? -56.061  -100.629 16.934  1.00 17.40  ? 1146 HOH D O     1 
HETATM 20386 O O     . HOH P 3 .   ? -66.219  -79.957  14.956  1.00 40.57  ? 1147 HOH D O     1 
HETATM 20387 O O     . HOH P 3 .   ? -56.540  -108.184 31.627  1.00 34.04  ? 1148 HOH D O     1 
HETATM 20388 O O     . HOH P 3 .   ? -68.723  -105.138 20.841  1.00 29.30  ? 1149 HOH D O     1 
HETATM 20389 O O     . HOH P 3 .   ? -67.051  -80.399  29.850  1.00 36.81  ? 1150 HOH D O     1 
HETATM 20390 O O     . HOH P 3 .   ? -69.268  -93.763  13.521  1.00 29.72  ? 1151 HOH D O     1 
HETATM 20391 O O     . HOH P 3 .   ? -62.827  -108.784 26.302  1.00 35.75  ? 1152 HOH D O     1 
HETATM 20392 O O     . HOH P 3 .   ? -38.597  -82.149  27.092  1.00 25.65  ? 1153 HOH D O     1 
HETATM 20393 O O     . HOH P 3 .   ? -20.902  -72.222  15.872  1.00 21.27  ? 1154 HOH D O     1 
HETATM 20394 O O     . HOH P 3 .   ? -39.505  -90.387  4.942   1.00 20.31  ? 1155 HOH D O     1 
HETATM 20395 O O     . HOH P 3 .   ? -6.731   -78.085  14.496  1.00 28.53  ? 1156 HOH D O     1 
HETATM 20396 O O     . HOH P 3 .   ? -19.551  -68.823  11.526  1.00 30.94  ? 1157 HOH D O     1 
HETATM 20397 O O     . HOH P 3 .   ? -47.352  -101.774 12.188  1.00 15.57  ? 1158 HOH D O     1 
HETATM 20398 O O     . HOH P 3 .   ? -21.214  -85.482  10.078  1.00 34.26  ? 1159 HOH D O     1 
HETATM 20399 O O     . HOH P 3 .   ? -15.168  -72.537  11.164  1.00 28.78  ? 1160 HOH D O     1 
HETATM 20400 O O     . HOH P 3 .   ? -56.706  -93.982  -1.684  1.00 32.15  ? 1161 HOH D O     1 
HETATM 20401 O O     . HOH P 3 .   ? -17.091  -66.981  26.705  1.00 29.16  ? 1162 HOH D O     1 
HETATM 20402 O O     . HOH P 3 .   ? -43.614  -84.213  15.611  1.00 31.36  ? 1163 HOH D O     1 
HETATM 20403 O O     . HOH P 3 .   ? -61.421  -78.688  28.260  1.00 30.15  ? 1164 HOH D O     1 
HETATM 20404 O O     . HOH P 3 .   ? -33.733  -89.943  32.409  1.00 33.14  ? 1165 HOH D O     1 
HETATM 20405 O O     . HOH P 3 .   ? -76.482  -94.829  22.094  1.00 27.74  ? 1166 HOH D O     1 
HETATM 20406 O O     . HOH P 3 .   ? -65.878  -93.669  32.884  1.00 36.93  ? 1167 HOH D O     1 
HETATM 20407 O O     . HOH P 3 .   ? -53.769  -104.232 0.501   1.00 36.05  ? 1168 HOH D O     1 
HETATM 20408 O O     . HOH P 3 .   ? -64.030  -80.006  24.142  1.00 29.90  ? 1169 HOH D O     1 
HETATM 20409 O O     . HOH P 3 .   ? -21.575  -95.152  21.617  1.00 26.85  ? 1170 HOH D O     1 
HETATM 20410 O O     . HOH P 3 .   ? -23.132  -75.899  11.863  1.00 27.48  ? 1171 HOH D O     1 
HETATM 20411 O O     . HOH P 3 .   ? -58.423  -104.948 31.332  1.00 20.15  ? 1172 HOH D O     1 
HETATM 20412 O O     . HOH P 3 .   ? -52.711  -112.053 7.889   1.00 42.90  ? 1173 HOH D O     1 
HETATM 20413 O O     . HOH P 3 .   ? -32.802  -104.398 19.724  1.00 43.49  ? 1174 HOH D O     1 
HETATM 20414 O O     . HOH P 3 .   ? -23.455  -94.057  28.005  1.00 39.00  ? 1175 HOH D O     1 
HETATM 20415 O O     . HOH P 3 .   ? -31.359  -77.948  16.070  1.00 23.27  ? 1176 HOH D O     1 
HETATM 20416 O O     . HOH P 3 .   ? -40.589  -100.345 4.747   1.00 33.44  ? 1177 HOH D O     1 
HETATM 20417 O O     . HOH P 3 .   ? -70.443  -99.459  19.596  1.00 33.94  ? 1178 HOH D O     1 
HETATM 20418 O O     . HOH P 3 .   ? -14.991  -80.372  9.990   1.00 23.90  ? 1179 HOH D O     1 
HETATM 20419 O O     . HOH P 3 .   ? -8.082   -88.928  11.674  1.00 28.70  ? 1180 HOH D O     1 
HETATM 20420 O O     . HOH P 3 .   ? -36.669  -106.570 28.378  1.00 25.48  ? 1181 HOH D O     1 
HETATM 20421 O O     . HOH P 3 .   ? -70.437  -83.138  22.782  1.00 44.36  ? 1182 HOH D O     1 
HETATM 20422 O O     . HOH P 3 .   ? -37.299  -112.382 25.314  1.00 43.36  ? 1183 HOH D O     1 
HETATM 20423 O O     . HOH P 3 .   ? -31.167  -73.716  30.923  1.00 36.98  ? 1184 HOH D O     1 
HETATM 20424 O O     . HOH P 3 .   ? -67.674  -100.686 4.701   1.00 36.56  ? 1185 HOH D O     1 
HETATM 20425 O O     . HOH P 3 .   ? -43.232  -111.017 11.423  1.00 43.74  ? 1186 HOH D O     1 
HETATM 20426 O O     . HOH P 3 .   ? -63.219  -87.114  24.970  1.00 24.83  ? 1187 HOH D O     1 
HETATM 20427 O O     . HOH P 3 .   ? -27.845  -96.493  24.002  1.00 30.45  ? 1188 HOH D O     1 
HETATM 20428 O O     . HOH P 3 .   ? -37.534  -94.452  32.554  1.00 23.15  ? 1189 HOH D O     1 
HETATM 20429 O O     . HOH P 3 .   ? -9.896   -78.500  13.286  1.00 28.97  ? 1190 HOH D O     1 
HETATM 20430 O O     . HOH P 3 .   ? -55.930  -97.281  12.335  1.00 16.49  ? 1191 HOH D O     1 
HETATM 20431 O O     . HOH P 3 .   ? -18.120  -77.158  35.068  1.00 32.30  ? 1192 HOH D O     1 
HETATM 20432 O O     . HOH P 3 .   ? -33.334  -82.230  35.267  1.00 39.61  ? 1193 HOH D O     1 
HETATM 20433 O O     . HOH P 3 .   ? -52.479  -81.020  36.367  1.00 34.32  ? 1194 HOH D O     1 
HETATM 20434 O O     . HOH P 3 .   ? -56.677  -99.080  8.939   1.00 18.70  ? 1195 HOH D O     1 
HETATM 20435 O O     . HOH P 3 .   ? -49.040  -92.848  37.382  1.00 43.33  ? 1196 HOH D O     1 
HETATM 20436 O O     . HOH P 3 .   ? -14.791  -90.803  17.708  1.00 27.54  ? 1197 HOH D O     1 
HETATM 20437 O O     . HOH P 3 .   ? -49.627  -101.039 8.639   1.00 19.25  ? 1198 HOH D O     1 
HETATM 20438 O O     . HOH P 3 .   ? -7.933   -80.311  19.841  1.00 27.17  ? 1199 HOH D O     1 
HETATM 20439 O O     . HOH P 3 .   ? -26.206  -99.995  19.154  1.00 29.84  ? 1200 HOH D O     1 
HETATM 20440 O O     . HOH P 3 .   ? -44.960  -86.089  19.798  1.00 30.33  ? 1201 HOH D O     1 
HETATM 20441 O O     . HOH P 3 .   ? -39.582  -108.365 17.787  1.00 26.47  ? 1202 HOH D O     1 
HETATM 20442 O O     . HOH P 3 .   ? -50.527  -92.203  39.168  1.00 35.15  ? 1203 HOH D O     1 
HETATM 20443 O O     . HOH P 3 .   ? -67.054  -101.848 20.035  1.00 28.18  ? 1204 HOH D O     1 
HETATM 20444 O O     . HOH P 3 .   ? -24.196  -82.531  11.069  1.00 25.81  ? 1205 HOH D O     1 
HETATM 20445 O O     . HOH P 3 .   ? -12.898  -79.561  11.768  1.00 22.24  ? 1206 HOH D O     1 
HETATM 20446 O O     . HOH P 3 .   ? -64.886  -87.649  35.509  1.00 39.32  ? 1207 HOH D O     1 
HETATM 20447 O O     . HOH P 3 .   ? -9.126   -77.729  19.277  1.00 25.28  ? 1208 HOH D O     1 
HETATM 20448 O O     . HOH P 3 .   ? -20.216  -90.436  26.728  1.00 30.08  ? 1209 HOH D O     1 
HETATM 20449 O O     . HOH P 3 .   ? -46.329  -78.038  35.332  1.00 28.96  ? 1210 HOH D O     1 
HETATM 20450 O O     . HOH P 3 .   ? -38.643  -106.427 30.177  1.00 32.63  ? 1211 HOH D O     1 
HETATM 20451 O O     . HOH P 3 .   ? -18.472  -52.709  20.465  1.00 24.53  ? 1212 HOH D O     1 
HETATM 20452 O O     . HOH P 3 .   ? -62.322  -96.200  22.620  1.00 22.51  ? 1213 HOH D O     1 
HETATM 20453 O O     . HOH P 3 .   ? -56.140  -96.118  41.065  1.00 18.72  ? 1214 HOH D O     1 
HETATM 20454 O O     . HOH P 3 .   ? -65.385  -87.313  28.426  1.00 20.13  ? 1215 HOH D O     1 
HETATM 20455 O O     . HOH P 3 .   ? -56.929  -82.660  24.041  1.00 45.42  ? 1216 HOH D O     1 
HETATM 20456 O O     . HOH P 3 .   ? -50.644  -112.407 28.700  1.00 34.32  ? 1217 HOH D O     1 
HETATM 20457 O O     . HOH P 3 .   ? -67.729  -93.727  30.548  1.00 39.35  ? 1218 HOH D O     1 
HETATM 20458 O O     . HOH P 3 .   ? -69.070  -102.326 21.799  1.00 28.91  ? 1219 HOH D O     1 
HETATM 20459 O O     . HOH P 3 .   ? -38.173  -107.708 9.271   1.00 34.54  ? 1220 HOH D O     1 
HETATM 20460 O O     . HOH P 3 .   ? -53.897  -99.152  35.354  1.00 20.72  ? 1221 HOH D O     1 
HETATM 20461 O O     . HOH P 3 .   ? -19.340  -86.390  20.485  1.00 22.56  ? 1222 HOH D O     1 
HETATM 20462 O O     . HOH P 3 .   ? -37.462  -88.971  -0.927  1.00 37.13  ? 1223 HOH D O     1 
HETATM 20463 O O     . HOH P 3 .   ? -13.371  -65.770  21.154  1.00 29.93  ? 1224 HOH D O     1 
HETATM 20464 O O     . HOH P 3 .   ? -42.345  -88.661  7.959   1.00 21.30  ? 1225 HOH D O     1 
HETATM 20465 O O     . HOH P 3 .   ? -77.658  -91.322  23.560  1.00 42.71  ? 1226 HOH D O     1 
HETATM 20466 O O     . HOH P 3 .   ? -28.088  -93.046  26.585  1.00 30.99  ? 1227 HOH D O     1 
HETATM 20467 O O     . HOH P 3 .   ? -45.597  -98.504  35.419  1.00 29.05  ? 1228 HOH D O     1 
HETATM 20468 O O     . HOH P 3 .   ? -60.053  -80.071  33.618  1.00 30.75  ? 1229 HOH D O     1 
HETATM 20469 O O     . HOH P 3 .   ? -46.736  -107.399 8.513   1.00 28.44  ? 1230 HOH D O     1 
HETATM 20470 O O     . HOH P 3 .   ? -18.827  -85.776  7.616   1.00 43.05  ? 1231 HOH D O     1 
HETATM 20471 O O     . HOH P 3 .   ? -31.021  -82.805  26.497  1.00 37.28  ? 1232 HOH D O     1 
HETATM 20472 O O     . HOH P 3 .   ? -51.896  -105.840 1.698   1.00 37.64  ? 1233 HOH D O     1 
HETATM 20473 O O     . HOH P 3 .   ? -52.234  -85.162  40.202  1.00 36.86  ? 1234 HOH D O     1 
HETATM 20474 O O     . HOH P 3 .   ? -43.614  -97.749  8.368   1.00 26.50  ? 1235 HOH D O     1 
HETATM 20475 O O     . HOH P 3 .   ? -12.410  -93.892  14.481  1.00 31.48  ? 1236 HOH D O     1 
HETATM 20476 O O     . HOH P 3 .   ? -54.293  -111.990 29.398  1.00 49.12  ? 1237 HOH D O     1 
HETATM 20477 O O     . HOH P 3 .   ? -31.411  -105.452 11.233  1.00 35.39  ? 1238 HOH D O     1 
HETATM 20478 O O     . HOH P 3 .   ? -44.190  -87.292  40.445  1.00 38.75  ? 1239 HOH D O     1 
HETATM 20479 O O     . HOH P 3 .   ? -70.289  -81.025  20.569  1.00 45.43  ? 1240 HOH D O     1 
HETATM 20480 O O     . HOH P 3 .   ? -35.961  -89.978  2.605   1.00 28.85  ? 1241 HOH D O     1 
HETATM 20481 O O     . HOH P 3 .   ? -15.654  -86.125  5.786   1.00 41.66  ? 1242 HOH D O     1 
HETATM 20482 O O     . HOH P 3 .   ? -46.668  -88.431  9.265   1.00 29.03  ? 1243 HOH D O     1 
HETATM 20483 O O     . HOH P 3 .   ? -44.982  -89.093  7.246   1.00 26.31  ? 1244 HOH D O     1 
HETATM 20484 O O     . HOH P 3 .   ? -52.155  -107.596 13.003  1.00 25.27  ? 1245 HOH D O     1 
HETATM 20485 O O     . HOH P 3 .   ? -43.248  -89.298  37.965  1.00 38.81  ? 1246 HOH D O     1 
HETATM 20486 O O     . HOH P 3 .   ? -51.014  -110.912 15.068  1.00 32.49  ? 1247 HOH D O     1 
HETATM 20487 O O     . HOH P 3 .   ? -33.982  -80.131  26.365  1.00 20.87  ? 1248 HOH D O     1 
HETATM 20488 O O     . HOH P 3 .   ? -45.645  -90.332  34.962  1.00 22.15  ? 1249 HOH D O     1 
HETATM 20489 O O     . HOH P 3 .   ? -65.475  -102.137 30.548  1.00 32.86  ? 1250 HOH D O     1 
HETATM 20490 O O     . HOH P 3 .   ? -57.626  -110.658 30.489  1.00 37.18  ? 1251 HOH D O     1 
HETATM 20491 O O     . HOH P 3 .   ? -9.637   -85.697  15.062  1.00 29.21  ? 1252 HOH D O     1 
HETATM 20492 O O     . HOH P 3 .   ? -62.727  -80.329  12.416  1.00 39.99  ? 1253 HOH D O     1 
HETATM 20493 O O     . HOH P 3 .   ? -64.575  -89.039  26.618  1.00 22.76  ? 1254 HOH D O     1 
HETATM 20494 O O     . HOH P 3 .   ? -5.569   -74.620  9.845   1.00 29.50  ? 1255 HOH D O     1 
HETATM 20495 O O     . HOH P 3 .   ? -42.538  -99.673  7.037   1.00 25.06  ? 1256 HOH D O     1 
HETATM 20496 O O     . HOH P 3 .   ? -46.325  -84.076  39.850  1.00 29.16  ? 1257 HOH D O     1 
HETATM 20497 O O     . HOH P 3 .   ? -60.676  -86.632  23.734  1.00 22.77  ? 1258 HOH D O     1 
HETATM 20498 O O     . HOH P 3 .   ? -30.094  -80.684  15.019  1.00 30.05  ? 1259 HOH D O     1 
HETATM 20499 O O     . HOH P 3 .   ? -48.549  -91.067  6.348   1.00 23.41  ? 1260 HOH D O     1 
HETATM 20500 O O     . HOH P 3 .   ? -41.682  -88.306  10.667  1.00 23.88  ? 1261 HOH D O     1 
HETATM 20501 O O     . HOH P 3 .   ? -6.555   -84.171  24.109  1.00 29.42  ? 1262 HOH D O     1 
HETATM 20502 O O     . HOH P 3 .   ? -28.192  -86.264  30.770  1.00 20.68  ? 1263 HOH D O     1 
HETATM 20503 O O     . HOH P 3 .   ? -50.343  -104.529 35.015  1.00 40.04  ? 1264 HOH D O     1 
HETATM 20504 O O     . HOH P 3 .   ? -28.802  -80.859  35.491  1.00 34.11  ? 1265 HOH D O     1 
HETATM 20505 O O     . HOH P 3 .   ? -12.051  -61.917  28.021  1.00 33.10  ? 1266 HOH D O     1 
HETATM 20506 O O     . HOH P 3 .   ? -44.070  -109.208 30.001  1.00 32.80  ? 1267 HOH D O     1 
HETATM 20507 O O     . HOH P 3 .   ? -59.349  -81.222  21.950  1.00 35.76  ? 1268 HOH D O     1 
HETATM 20508 O O     . HOH P 3 .   ? -37.592  -104.387 7.566   1.00 36.09  ? 1269 HOH D O     1 
HETATM 20509 O O     . HOH P 3 .   ? -46.842  -89.288  3.035   1.00 21.89  ? 1270 HOH D O     1 
HETATM 20510 O O     . HOH P 3 .   ? -46.713  -75.657  36.597  1.00 31.97  ? 1271 HOH D O     1 
HETATM 20511 O O     . HOH P 3 .   ? -69.784  -79.878  28.927  1.00 43.28  ? 1272 HOH D O     1 
HETATM 20512 O O     . HOH P 3 .   ? -7.132   -73.228  24.514  1.00 31.42  ? 1273 HOH D O     1 
HETATM 20513 O O     . HOH P 3 .   ? -58.304  -79.232  36.069  1.00 40.84  ? 1274 HOH D O     1 
HETATM 20514 O O     . HOH P 3 .   ? -9.907   -90.655  18.627  1.00 30.71  ? 1275 HOH D O     1 
HETATM 20515 O O     . HOH P 3 .   ? -63.572  -80.137  26.741  1.00 29.44  ? 1276 HOH D O     1 
HETATM 20516 O O     . HOH P 3 .   ? -11.703  -59.103  23.415  1.00 37.34  ? 1277 HOH D O     1 
HETATM 20517 O O     . HOH P 3 .   ? -43.314  -88.711  35.152  1.00 27.59  ? 1278 HOH D O     1 
HETATM 20518 O O     . HOH P 3 .   ? -69.061  -103.453 5.768   1.00 40.62  ? 1279 HOH D O     1 
HETATM 20519 O O     . HOH P 3 .   ? -50.648  -80.374  19.641  1.00 37.94  ? 1280 HOH D O     1 
HETATM 20520 O O     . HOH P 3 .   ? -20.837  -83.107  7.373   1.00 42.17  ? 1281 HOH D O     1 
HETATM 20521 O O     . HOH P 3 .   ? -51.719  -82.473  39.222  1.00 36.07  ? 1282 HOH D O     1 
HETATM 20522 O O     . HOH P 3 .   ? -37.218  -86.199  5.457   1.00 42.42  ? 1283 HOH D O     1 
HETATM 20523 O O     . HOH P 3 .   ? -74.007  -91.900  27.569  1.00 39.32  ? 1284 HOH D O     1 
HETATM 20524 O O     . HOH P 3 .   ? -54.710  -99.216  38.183  1.00 21.99  ? 1285 HOH D O     1 
HETATM 20525 O O     . HOH P 3 .   ? -36.636  -83.772  37.394  1.00 44.28  ? 1286 HOH D O     1 
HETATM 20526 O O     . HOH P 3 .   ? -57.456  -106.770 36.018  1.00 41.34  ? 1287 HOH D O     1 
HETATM 20527 O O     . HOH P 3 .   ? -30.639  -77.821  33.236  1.00 33.84  ? 1288 HOH D O     1 
HETATM 20528 O O     . HOH P 3 .   ? -14.828  -60.184  20.473  1.00 36.70  ? 1289 HOH D O     1 
HETATM 20529 O O     . HOH P 3 .   ? -46.225  -111.051 10.308  1.00 42.89  ? 1290 HOH D O     1 
HETATM 20530 O O     . HOH P 3 .   ? -66.003  -100.976 40.292  1.00 47.16  ? 1291 HOH D O     1 
HETATM 20531 O O     . HOH P 3 .   ? -59.083  -82.975  37.359  1.00 37.08  ? 1292 HOH D O     1 
HETATM 20532 O O     . HOH P 3 .   ? -8.132   -87.895  22.695  1.00 40.85  ? 1293 HOH D O     1 
HETATM 20533 O O     . HOH P 3 .   ? -39.824  -86.444  39.205  1.00 42.16  ? 1294 HOH D O     1 
HETATM 20534 O O     . HOH P 3 .   ? -42.816  -97.464  10.929  1.00 30.99  ? 1295 HOH D O     1 
HETATM 20535 O O     . HOH P 3 .   ? -24.793  -100.115 14.264  1.00 35.59  ? 1296 HOH D O     1 
HETATM 20536 O O     . HOH P 3 .   ? -48.357  -91.388  3.665   1.00 25.32  ? 1297 HOH D O     1 
HETATM 20537 O O     . HOH P 3 .   ? -24.910  -70.730  30.712  1.00 53.02  ? 1298 HOH D O     1 
HETATM 20538 O O     . HOH P 3 .   ? -37.305  -78.066  28.563  1.00 29.37  ? 1299 HOH D O     1 
HETATM 20539 O O     . HOH P 3 .   ? -5.090   -83.391  19.981  1.00 35.55  ? 1300 HOH D O     1 
HETATM 20540 O O     . HOH P 3 .   ? -27.143  -102.801 12.889  1.00 40.53  ? 1301 HOH D O     1 
HETATM 20541 O O     . HOH P 3 .   ? -39.434  -87.118  1.562   1.00 42.81  ? 1302 HOH D O     1 
HETATM 20542 O O     . HOH P 3 .   ? -28.850  -84.652  7.636   1.00 49.18  ? 1303 HOH D O     1 
HETATM 20543 O O     . HOH P 3 .   ? -47.387  -82.519  15.142  1.00 42.88  ? 1304 HOH D O     1 
HETATM 20544 O O     . HOH P 3 .   ? -57.163  -96.481  -2.604  1.00 39.80  ? 1305 HOH D O     1 
HETATM 20545 O O     . HOH P 3 .   ? -36.464  -80.356  27.607  1.00 26.54  ? 1306 HOH D O     1 
HETATM 20546 O O     . HOH P 3 .   ? -70.166  -97.146  26.153  1.00 37.57  ? 1307 HOH D O     1 
HETATM 20547 O O     . HOH P 3 .   ? -65.329  -77.473  23.779  1.00 39.55  ? 1308 HOH D O     1 
HETATM 20548 O O     . HOH P 3 .   ? -69.378  -101.165 18.191  1.00 44.80  ? 1309 HOH D O     1 
HETATM 20549 O O     . HOH P 3 .   ? -49.089  -111.178 9.776   1.00 43.31  ? 1310 HOH D O     1 
HETATM 20550 O O     . HOH P 3 .   ? -38.045  -88.300  3.883   1.00 37.17  ? 1311 HOH D O     1 
HETATM 20551 O O     . HOH P 3 .   ? -37.135  -104.314 38.207  1.00 33.43  ? 1312 HOH D O     1 
HETATM 20552 O O     . HOH P 3 .   ? -18.737  -92.464  25.211  1.00 42.19  ? 1313 HOH D O     1 
HETATM 20553 O O     . HOH P 3 .   ? -61.490  -77.538  33.350  1.00 39.91  ? 1314 HOH D O     1 
HETATM 20554 O O     . HOH P 3 .   ? -21.074  -53.107  20.253  1.00 30.89  ? 1315 HOH D O     1 
HETATM 20555 O O     . HOH P 3 .   ? -28.507  -88.056  33.016  1.00 36.42  ? 1316 HOH D O     1 
HETATM 20556 O O     . HOH P 3 .   ? -75.923  -90.254  25.802  1.00 41.94  ? 1317 HOH D O     1 
HETATM 20557 O O     . HOH P 3 .   ? -73.762  -94.290  26.638  1.00 34.36  ? 1318 HOH D O     1 
HETATM 20558 O O     . HOH P 3 .   ? -63.655  -111.736 27.036  1.00 43.02  ? 1319 HOH D O     1 
HETATM 20559 O O     . HOH P 3 .   ? -27.750  -95.823  26.388  1.00 36.70  ? 1320 HOH D O     1 
HETATM 20560 O O     . HOH P 3 .   ? -74.399  -98.235  11.556  1.00 31.04  ? 1321 HOH D O     1 
HETATM 20561 O O     . HOH P 3 .   ? -54.200  -111.274 5.750   1.00 50.38  ? 1322 HOH D O     1 
HETATM 20562 O O     . HOH P 3 .   ? -7.856   -87.312  13.871  1.00 33.68  ? 1323 HOH D O     1 
HETATM 20563 O O     . HOH P 3 .   ? -40.155  -103.729 7.215   1.00 35.08  ? 1324 HOH D O     1 
HETATM 20564 O O     . HOH P 3 .   ? -31.984  -75.339  32.575  1.00 38.33  ? 1325 HOH D O     1 
HETATM 20565 O O     . HOH P 3 .   ? -7.421   -82.251  13.968  1.00 36.51  ? 1326 HOH D O     1 
HETATM 20566 O O     . HOH P 3 .   ? -7.587   -89.261  15.422  1.00 40.67  ? 1327 HOH D O     1 
HETATM 20567 O O     . HOH P 3 .   ? -64.314  -96.227  7.534   1.00 43.78  ? 1328 HOH D O     1 
HETATM 20568 O O     . HOH Q 3 .   ? -53.869  13.930   -11.515 1.00 44.82  ? 1101 HOH E O     1 
HETATM 20569 O O     . HOH Q 3 .   ? -43.574  1.678    -20.278 1.00 47.78  ? 1102 HOH E O     1 
HETATM 20570 O O     . HOH Q 3 .   ? -60.211  -18.363  -61.482 1.00 21.14  ? 1103 HOH E O     1 
HETATM 20571 O O     . HOH Q 3 .   ? -53.569  21.290   -17.580 1.00 44.89  ? 1104 HOH E O     1 
HETATM 20572 O O     . HOH Q 3 .   ? -68.652  -9.346   -39.361 1.00 24.86  ? 1105 HOH E O     1 
HETATM 20573 O O     . HOH Q 3 .   ? -59.768  -27.446  -47.876 1.00 19.16  ? 1106 HOH E O     1 
HETATM 20574 O O     . HOH Q 3 .   ? -66.314  -21.438  -61.806 1.00 24.33  ? 1107 HOH E O     1 
HETATM 20575 O O     . HOH Q 3 .   ? -55.086  23.566   -51.348 1.00 39.88  ? 1108 HOH E O     1 
HETATM 20576 O O     . HOH Q 3 .   ? -67.535  -21.685  -66.165 1.00 32.88  ? 1109 HOH E O     1 
HETATM 20577 O O     . HOH Q 3 .   ? -68.811  -9.330   -35.013 1.00 38.55  ? 1110 HOH E O     1 
HETATM 20578 O O     . HOH Q 3 .   ? -72.293  -3.968   -72.743 1.00 41.58  ? 1111 HOH E O     1 
HETATM 20579 O O     . HOH Q 3 .   ? -54.904  22.022   -20.102 1.00 36.91  ? 1112 HOH E O     1 
HETATM 20580 O O     . HOH Q 3 .   ? -71.068  2.932    -17.154 1.00 36.62  ? 1113 HOH E O     1 
HETATM 20581 O O     . HOH Q 3 .   ? -68.321  5.806    -41.056 1.00 38.45  ? 1114 HOH E O     1 
HETATM 20582 O O     . HOH Q 3 .   ? -64.462  21.770   -35.898 1.00 41.16  ? 1115 HOH E O     1 
HETATM 20583 O O     . HOH Q 3 .   ? -81.636  -5.371   -77.791 1.00 41.67  ? 1116 HOH E O     1 
HETATM 20584 O O     . HOH Q 3 .   ? -56.717  -16.307  -56.827 1.00 26.49  ? 1117 HOH E O     1 
HETATM 20585 O O     . HOH Q 3 .   ? -74.972  -3.544   -56.457 1.00 41.55  ? 1118 HOH E O     1 
HETATM 20586 O O     . HOH Q 3 .   ? -56.015  2.521    -27.838 1.00 22.42  ? 1119 HOH E O     1 
HETATM 20587 O O     . HOH Q 3 .   ? -79.853  0.388    -70.683 1.00 38.47  ? 1120 HOH E O     1 
HETATM 20588 O O     . HOH Q 3 .   ? -79.034  -12.036  -60.966 1.00 25.30  ? 1121 HOH E O     1 
HETATM 20589 O O     . HOH Q 3 .   ? -72.109  -0.320   -60.039 1.00 28.99  ? 1122 HOH E O     1 
HETATM 20590 O O     . HOH Q 3 .   ? -57.467  19.597   -22.777 1.00 25.85  ? 1123 HOH E O     1 
HETATM 20591 O O     . HOH Q 3 .   ? -59.738  2.296    -21.642 1.00 27.55  ? 1124 HOH E O     1 
HETATM 20592 O O     . HOH Q 3 .   ? -55.974  10.222   -27.780 1.00 23.94  ? 1125 HOH E O     1 
HETATM 20593 O O     . HOH Q 3 .   ? -74.835  -5.720   -79.165 1.00 38.05  ? 1126 HOH E O     1 
HETATM 20594 O O     . HOH Q 3 .   ? -68.461  -11.451  -51.070 1.00 26.66  ? 1127 HOH E O     1 
HETATM 20595 O O     . HOH Q 3 .   ? -60.095  -1.639   -34.289 1.00 32.91  ? 1128 HOH E O     1 
HETATM 20596 O O     . HOH Q 3 .   ? -53.559  -6.528   -59.125 1.00 30.94  ? 1129 HOH E O     1 
HETATM 20597 O O     . HOH Q 3 .   ? -47.514  22.484   -38.709 1.00 28.92  ? 1130 HOH E O     1 
HETATM 20598 O O     . HOH Q 3 .   ? -60.058  8.445    -61.668 1.00 36.52  ? 1131 HOH E O     1 
HETATM 20599 O O     . HOH Q 3 .   ? -87.667  -3.988   -75.299 1.00 35.51  ? 1132 HOH E O     1 
HETATM 20600 O O     . HOH Q 3 .   ? -60.055  -7.006   -28.314 1.00 32.85  ? 1133 HOH E O     1 
HETATM 20601 O O     . HOH Q 3 .   ? -69.451  28.105   -39.682 1.00 43.52  ? 1134 HOH E O     1 
HETATM 20602 O O     . HOH Q 3 .   ? -42.080  19.685   -30.865 1.00 42.79  ? 1135 HOH E O     1 
HETATM 20603 O O     . HOH Q 3 .   ? -53.620  -19.278  -50.732 1.00 22.77  ? 1136 HOH E O     1 
HETATM 20604 O O     . HOH Q 3 .   ? -62.584  -11.705  -71.974 1.00 28.28  ? 1137 HOH E O     1 
HETATM 20605 O O     . HOH Q 3 .   ? -66.468  -18.422  -50.752 1.00 42.05  ? 1138 HOH E O     1 
HETATM 20606 O O     . HOH Q 3 .   ? -62.936  -17.937  -67.531 1.00 28.65  ? 1139 HOH E O     1 
HETATM 20607 O O     . HOH Q 3 .   ? -53.111  -1.240   -22.976 1.00 29.40  ? 1140 HOH E O     1 
HETATM 20608 O O     . HOH Q 3 .   ? -56.084  12.248   -25.621 1.00 27.90  ? 1141 HOH E O     1 
HETATM 20609 O O     . HOH Q 3 .   ? -66.790  -13.747  -52.917 1.00 33.31  ? 1142 HOH E O     1 
HETATM 20610 O O     . HOH Q 3 .   ? -59.674  -0.423   -72.025 1.00 36.36  ? 1143 HOH E O     1 
HETATM 20611 O O     . HOH Q 3 .   ? -75.336  -16.459  -61.679 1.00 31.42  ? 1144 HOH E O     1 
HETATM 20612 O O     . HOH Q 3 .   ? -60.474  -11.912  -20.163 1.00 32.25  ? 1145 HOH E O     1 
HETATM 20613 O O     . HOH Q 3 .   ? -59.499  14.154   -18.366 1.00 36.88  ? 1146 HOH E O     1 
HETATM 20614 O O     . HOH Q 3 .   ? -68.115  -5.263   -33.970 1.00 22.39  ? 1147 HOH E O     1 
HETATM 20615 O O     . HOH Q 3 .   ? -61.527  -20.758  -61.024 1.00 27.34  ? 1148 HOH E O     1 
HETATM 20616 O O     . HOH Q 3 .   ? -67.126  0.418    -37.092 1.00 30.28  ? 1149 HOH E O     1 
HETATM 20617 O O     . HOH Q 3 .   ? -50.586  20.698   -46.265 1.00 43.39  ? 1150 HOH E O     1 
HETATM 20618 O O     . HOH Q 3 .   ? -68.151  -20.384  -63.326 1.00 22.12  ? 1151 HOH E O     1 
HETATM 20619 O O     . HOH Q 3 .   ? -53.327  7.038    -54.225 1.00 39.82  ? 1152 HOH E O     1 
HETATM 20620 O O     . HOH Q 3 .   ? -74.177  -8.844   -61.247 1.00 24.37  ? 1153 HOH E O     1 
HETATM 20621 O O     . HOH Q 3 .   ? -66.114  -15.201  -50.915 1.00 33.10  ? 1154 HOH E O     1 
HETATM 20622 O O     . HOH Q 3 .   ? -65.556  11.627   -51.630 1.00 38.92  ? 1155 HOH E O     1 
HETATM 20623 O O     . HOH Q 3 .   ? -72.803  -17.135  -57.567 1.00 27.10  ? 1156 HOH E O     1 
HETATM 20624 O O     . HOH Q 3 .   ? -61.245  12.844   -57.336 1.00 49.84  ? 1157 HOH E O     1 
HETATM 20625 O O     . HOH Q 3 .   ? -45.773  1.252    -32.235 1.00 37.51  ? 1158 HOH E O     1 
HETATM 20626 O O     . HOH Q 3 .   ? -52.145  -9.692   -52.754 1.00 35.13  ? 1159 HOH E O     1 
HETATM 20627 O O     . HOH Q 3 .   ? -38.641  12.322   -30.628 1.00 33.37  ? 1160 HOH E O     1 
HETATM 20628 O O     . HOH Q 3 .   ? -51.607  5.283    -22.539 1.00 41.90  ? 1161 HOH E O     1 
HETATM 20629 O O     . HOH Q 3 .   ? -57.833  21.743   -27.359 1.00 41.30  ? 1162 HOH E O     1 
HETATM 20630 O O     . HOH Q 3 .   ? -68.197  2.306    -28.886 1.00 28.81  ? 1163 HOH E O     1 
HETATM 20631 O O     . HOH Q 3 .   ? -55.166  -20.815  -54.794 1.00 33.47  ? 1164 HOH E O     1 
HETATM 20632 O O     . HOH Q 3 .   ? -72.000  -10.014  -32.373 1.00 40.46  ? 1165 HOH E O     1 
HETATM 20633 O O     . HOH Q 3 .   ? -65.614  -16.971  -67.720 1.00 22.82  ? 1166 HOH E O     1 
HETATM 20634 O O     . HOH Q 3 .   ? -58.676  -8.672   -26.886 1.00 35.03  ? 1167 HOH E O     1 
HETATM 20635 O O     . HOH Q 3 .   ? -58.860  2.232    -24.632 1.00 23.50  ? 1168 HOH E O     1 
HETATM 20636 O O     . HOH Q 3 .   ? -71.389  -2.037   -51.884 1.00 42.98  ? 1169 HOH E O     1 
HETATM 20637 O O     . HOH Q 3 .   ? -65.072  23.073   -33.603 1.00 36.11  ? 1170 HOH E O     1 
HETATM 20638 O O     . HOH Q 3 .   ? -57.379  -17.237  -68.958 1.00 36.19  ? 1171 HOH E O     1 
HETATM 20639 O O     . HOH Q 3 .   ? -48.053  2.985    -20.423 1.00 45.51  ? 1172 HOH E O     1 
HETATM 20640 O O     . HOH Q 3 .   ? -45.071  22.055   -30.650 1.00 31.03  ? 1173 HOH E O     1 
HETATM 20641 O O     . HOH Q 3 .   ? -40.167  9.246    -36.817 1.00 37.05  ? 1174 HOH E O     1 
HETATM 20642 O O     . HOH Q 3 .   ? -64.278  25.683   -32.676 1.00 33.59  ? 1175 HOH E O     1 
HETATM 20643 O O     . HOH Q 3 .   ? -47.949  -3.221   -25.696 1.00 38.53  ? 1176 HOH E O     1 
HETATM 20644 O O     . HOH Q 3 .   ? -73.577  -10.543  -55.424 1.00 26.12  ? 1177 HOH E O     1 
HETATM 20645 O O     . HOH Q 3 .   ? -59.846  -24.862  -58.339 1.00 28.87  ? 1178 HOH E O     1 
HETATM 20646 O O     . HOH Q 3 .   ? -47.421  4.877    -22.685 1.00 37.18  ? 1179 HOH E O     1 
HETATM 20647 O O     . HOH Q 3 .   ? -62.045  -20.974  -63.578 1.00 30.58  ? 1180 HOH E O     1 
HETATM 20648 O O     . HOH Q 3 .   ? -59.851  -10.305  -57.794 1.00 30.39  ? 1181 HOH E O     1 
HETATM 20649 O O     . HOH Q 3 .   ? -76.004  -11.818  -53.279 1.00 44.16  ? 1182 HOH E O     1 
HETATM 20650 O O     . HOH Q 3 .   ? -70.743  27.557   -35.092 1.00 40.33  ? 1183 HOH E O     1 
HETATM 20651 O O     . HOH Q 3 .   ? -63.090  31.132   -42.603 1.00 36.42  ? 1184 HOH E O     1 
HETATM 20652 O O     . HOH Q 3 .   ? -61.543  8.277    -21.079 1.00 25.68  ? 1185 HOH E O     1 
HETATM 20653 O O     . HOH Q 3 .   ? -69.279  -18.753  -57.321 1.00 24.80  ? 1186 HOH E O     1 
HETATM 20654 O O     . HOH Q 3 .   ? -60.876  -1.803   -29.824 1.00 35.07  ? 1187 HOH E O     1 
HETATM 20655 O O     . HOH Q 3 .   ? -45.334  21.439   -23.130 1.00 54.84  ? 1188 HOH E O     1 
HETATM 20656 O O     . HOH Q 3 .   ? -59.443  -3.786   -28.737 1.00 37.68  ? 1189 HOH E O     1 
HETATM 20657 O O     . HOH Q 3 .   ? -63.413  9.445    -52.111 1.00 29.91  ? 1190 HOH E O     1 
HETATM 20658 O O     . HOH Q 3 .   ? -64.532  5.799    -55.463 1.00 27.77  ? 1191 HOH E O     1 
HETATM 20659 O O     . HOH Q 3 .   ? -66.251  -14.154  -74.308 1.00 33.87  ? 1192 HOH E O     1 
HETATM 20660 O O     . HOH Q 3 .   ? -56.106  2.800    -58.422 1.00 32.26  ? 1193 HOH E O     1 
HETATM 20661 O O     . HOH Q 3 .   ? -48.338  25.054   -44.529 1.00 40.39  ? 1194 HOH E O     1 
HETATM 20662 O O     . HOH Q 3 .   ? -50.875  -10.904  -35.171 1.00 36.90  ? 1195 HOH E O     1 
HETATM 20663 O O     . HOH Q 3 .   ? -66.726  -22.028  -51.403 1.00 36.52  ? 1196 HOH E O     1 
HETATM 20664 O O     . HOH Q 3 .   ? -54.699  16.496   -50.417 1.00 39.74  ? 1197 HOH E O     1 
HETATM 20665 O O     . HOH Q 3 .   ? -69.766  22.102   -36.509 1.00 45.74  ? 1198 HOH E O     1 
HETATM 20666 O O     . HOH Q 3 .   ? -57.929  25.156   -18.158 1.00 29.80  ? 1199 HOH E O     1 
HETATM 20667 O O     . HOH Q 3 .   ? -62.100  27.189   -31.581 1.00 33.37  ? 1200 HOH E O     1 
HETATM 20668 O O     . HOH Q 3 .   ? -55.547  -19.532  -60.440 1.00 40.23  ? 1201 HOH E O     1 
HETATM 20669 O O     . HOH Q 3 .   ? -61.019  10.208   -24.496 1.00 26.83  ? 1202 HOH E O     1 
HETATM 20670 O O     . HOH Q 3 .   ? -69.333  28.811   -36.804 1.00 41.70  ? 1203 HOH E O     1 
HETATM 20671 O O     . HOH Q 3 .   ? -77.379  -2.566   -58.992 1.00 42.25  ? 1204 HOH E O     1 
HETATM 20672 O O     . HOH Q 3 .   ? -57.095  -5.150   -29.975 1.00 49.06  ? 1205 HOH E O     1 
HETATM 20673 O O     . HOH Q 3 .   ? -65.022  8.863    -41.424 1.00 39.73  ? 1206 HOH E O     1 
HETATM 20674 O O     . HOH Q 3 .   ? -68.672  -19.173  -59.940 1.00 24.19  ? 1207 HOH E O     1 
HETATM 20675 O O     . HOH Q 3 .   ? -60.801  14.226   -6.603  1.00 43.70  ? 1208 HOH E O     1 
HETATM 20676 O O     . HOH Q 3 .   ? -46.346  -1.674   -33.004 1.00 35.69  ? 1209 HOH E O     1 
HETATM 20677 O O     . HOH Q 3 .   ? -53.535  17.795   -48.079 1.00 34.06  ? 1210 HOH E O     1 
HETATM 20678 O O     . HOH Q 3 .   ? -43.618  24.121   -39.123 1.00 37.44  ? 1211 HOH E O     1 
HETATM 20679 O O     . HOH Q 3 .   ? -62.758  29.476   -32.937 1.00 41.31  ? 1212 HOH E O     1 
HETATM 20680 O O     . HOH Q 3 .   ? -68.746  -0.808   -35.019 1.00 24.85  ? 1213 HOH E O     1 
HETATM 20681 O O     . HOH Q 3 .   ? -51.064  -3.515   -50.036 1.00 35.41  ? 1214 HOH E O     1 
HETATM 20682 O O     . HOH Q 3 .   ? -50.083  -8.987   -45.665 1.00 40.66  ? 1215 HOH E O     1 
HETATM 20683 O O     . HOH Q 3 .   ? -52.248  1.934    -57.880 1.00 40.23  ? 1216 HOH E O     1 
HETATM 20684 O O     . HOH Q 3 .   ? -61.198  14.886   -9.360  1.00 39.79  ? 1217 HOH E O     1 
HETATM 20685 O O     . HOH Q 3 .   ? -71.250  -0.559   -28.767 1.00 28.93  ? 1218 HOH E O     1 
HETATM 20686 O O     . HOH Q 3 .   ? -58.661  7.679    -63.671 1.00 35.43  ? 1219 HOH E O     1 
HETATM 20687 O O     . HOH Q 3 .   ? -51.492  -7.517   -28.410 1.00 38.54  ? 1220 HOH E O     1 
HETATM 20688 O O     . HOH Q 3 .   ? -69.227  0.425    -27.103 1.00 33.98  ? 1221 HOH E O     1 
HETATM 20689 O O     . HOH Q 3 .   ? -72.783  -3.727   -52.810 1.00 38.87  ? 1222 HOH E O     1 
HETATM 20690 O O     . HOH Q 3 .   ? -71.149  -21.263  -59.759 1.00 41.17  ? 1223 HOH E O     1 
HETATM 20691 O O     . HOH Q 3 .   ? -65.448  30.332   -43.217 1.00 35.03  ? 1224 HOH E O     1 
HETATM 20692 O O     . HOH Q 3 .   ? -72.711  -24.887  -65.887 1.00 30.41  ? 1225 HOH E O     1 
HETATM 20693 O O     . HOH Q 3 .   ? -54.127  -8.327   -29.469 1.00 29.21  ? 1226 HOH E O     1 
HETATM 20694 O O     . HOH Q 3 .   ? -69.107  0.735    -32.814 1.00 31.49  ? 1227 HOH E O     1 
HETATM 20695 O O     . HOH Q 3 .   ? -80.501  -8.309   -73.745 1.00 35.00  ? 1228 HOH E O     1 
HETATM 20696 O O     . HOH Q 3 .   ? -48.835  29.283   -25.283 1.00 43.83  ? 1229 HOH E O     1 
HETATM 20697 O O     . HOH Q 3 .   ? -46.068  24.358   -43.146 1.00 37.19  ? 1230 HOH E O     1 
HETATM 20698 O O     . HOH Q 3 .   ? -52.374  -12.648  -43.679 1.00 32.52  ? 1231 HOH E O     1 
HETATM 20699 O O     . HOH Q 3 .   ? -45.823  24.852   -40.197 1.00 43.49  ? 1232 HOH E O     1 
HETATM 20700 O O     . HOH Q 3 .   ? -66.094  10.356   -55.536 1.00 39.61  ? 1233 HOH E O     1 
HETATM 20701 O O     . HOH Q 3 .   ? -70.524  8.632    -39.214 1.00 43.89  ? 1234 HOH E O     1 
HETATM 20702 O O     . HOH Q 3 .   ? -52.999  -12.467  -41.038 1.00 39.93  ? 1235 HOH E O     1 
HETATM 20703 O O     . HOH Q 3 .   ? -68.941  3.498    -68.149 1.00 48.79  ? 1236 HOH E O     1 
HETATM 20704 O O     . HOH Q 3 .   ? -51.006  -12.392  -39.719 1.00 42.12  ? 1237 HOH E O     1 
HETATM 20705 O O     . HOH Q 3 .   ? -64.298  8.574    -54.440 1.00 32.68  ? 1238 HOH E O     1 
HETATM 20706 O O     . HOH Q 3 .   ? -55.619  -2.600   -72.107 1.00 49.10  ? 1239 HOH E O     1 
HETATM 20707 O O     . HOH Q 3 .   ? -49.834  0.502    -20.638 1.00 50.72  ? 1240 HOH E O     1 
HETATM 20708 O O     . HOH Q 3 .   ? -56.310  6.028    -63.942 1.00 51.03  ? 1241 HOH E O     1 
HETATM 20709 O O     . HOH Q 3 .   ? -57.277  -0.989   -73.192 1.00 46.98  ? 1242 HOH E O     1 
HETATM 20710 O O     . HOH Q 3 .   ? -68.337  6.024    -68.030 1.00 51.92  ? 1243 HOH E O     1 
HETATM 20711 O O     . HOH Q 3 .   ? -88.039  -2.281   -73.514 1.00 36.08  ? 1244 HOH E O     1 
HETATM 20712 O O     . HOH Q 3 .   ? -74.685  -2.531   -54.210 1.00 56.98  ? 1245 HOH E O     1 
HETATM 20713 O O     . HOH Q 3 .   ? -59.925  -22.992  -60.405 1.00 30.30  ? 1246 HOH E O     1 
HETATM 20714 O O     . HOH Q 3 .   ? -63.094  32.580   -31.120 1.00 38.62  ? 1247 HOH E O     1 
HETATM 20715 O O     . HOH Q 3 .   ? -57.575  -20.911  -64.219 1.00 38.78  ? 1248 HOH E O     1 
HETATM 20716 O O     . HOH Q 3 .   ? -57.210  -22.115  -61.395 1.00 43.38  ? 1249 HOH E O     1 
HETATM 20717 O O     . HOH R 3 .   ? -41.000  -37.595  -55.323 1.00 40.06  ? 1101 HOH F O     1 
HETATM 20718 O O     . HOH R 3 .   ? -72.113  -26.909  -11.748 1.00 38.61  ? 1102 HOH F O     1 
HETATM 20719 O O     . HOH R 3 .   ? -41.816  -30.585  -30.447 1.00 28.70  ? 1103 HOH F O     1 
HETATM 20720 O O     . HOH R 3 .   ? -53.506  -15.322  -45.160 1.00 41.22  ? 1104 HOH F O     1 
HETATM 20721 O O     . HOH R 3 .   ? -73.120  -5.779   -16.488 1.00 27.94  ? 1105 HOH F O     1 
HETATM 20722 O O     . HOH R 3 .   ? -65.928  3.505    -27.762 1.00 26.24  ? 1106 HOH F O     1 
HETATM 20723 O O     . HOH R 3 .   ? -78.465  -6.215   -12.640 1.00 34.27  ? 1107 HOH F O     1 
HETATM 20724 O O     . HOH R 3 .   ? -63.254  -31.092  -19.168 1.00 42.67  ? 1108 HOH F O     1 
HETATM 20725 O O     . HOH R 3 .   ? -44.718  -48.547  -48.271 1.00 30.28  ? 1109 HOH F O     1 
HETATM 20726 O O     . HOH R 3 .   ? -74.237  -10.438  -27.029 1.00 28.00  ? 1110 HOH F O     1 
HETATM 20727 O O     . HOH R 3 .   ? -37.088  -25.135  -42.570 1.00 35.91  ? 1111 HOH F O     1 
HETATM 20728 O O     . HOH R 3 .   ? -82.355  -23.997  -23.887 1.00 22.46  ? 1112 HOH F O     1 
HETATM 20729 O O     . HOH R 3 .   ? -62.099  -4.498   -22.011 1.00 23.10  ? 1113 HOH F O     1 
HETATM 20730 O O     . HOH R 3 .   ? -81.699  -2.585   -16.035 1.00 38.22  ? 1114 HOH F O     1 
HETATM 20731 O O     . HOH R 3 .   ? -43.635  -20.660  -40.320 1.00 38.54  ? 1115 HOH F O     1 
HETATM 20732 O O     . HOH R 3 .   ? -37.973  -35.719  -31.354 1.00 40.70  ? 1116 HOH F O     1 
HETATM 20733 O O     . HOH R 3 .   ? -68.537  -14.572  -39.643 1.00 21.45  ? 1117 HOH F O     1 
HETATM 20734 O O     . HOH R 3 .   ? -65.202  -18.838  -43.954 1.00 21.79  ? 1118 HOH F O     1 
HETATM 20735 O O     . HOH R 3 .   ? -71.292  -47.281  -32.307 1.00 40.87  ? 1119 HOH F O     1 
HETATM 20736 O O     . HOH R 3 .   ? -49.305  -37.933  -52.379 1.00 28.60  ? 1120 HOH F O     1 
HETATM 20737 O O     . HOH R 3 .   ? -64.673  -36.077  -17.257 1.00 42.89  ? 1121 HOH F O     1 
HETATM 20738 O O     . HOH R 3 .   ? -94.618  -24.632  -19.010 1.00 32.14  ? 1122 HOH F O     1 
HETATM 20739 O O     . HOH R 3 .   ? -49.663  -43.496  -47.732 1.00 25.93  ? 1123 HOH F O     1 
HETATM 20740 O O     . HOH R 3 .   ? -39.668  -44.751  -40.774 1.00 37.41  ? 1124 HOH F O     1 
HETATM 20741 O O     . HOH R 3 .   ? -62.543  -45.734  -40.337 1.00 31.57  ? 1125 HOH F O     1 
HETATM 20742 O O     . HOH R 3 .   ? -43.568  -44.401  -50.320 1.00 35.85  ? 1126 HOH F O     1 
HETATM 20743 O O     . HOH R 3 .   ? -71.836  -45.478  -25.009 1.00 39.58  ? 1127 HOH F O     1 
HETATM 20744 O O     . HOH R 3 .   ? -48.135  -22.069  -53.447 1.00 32.43  ? 1128 HOH F O     1 
HETATM 20745 O O     . HOH R 3 .   ? -50.072  -36.023  -44.498 1.00 16.64  ? 1129 HOH F O     1 
HETATM 20746 O O     . HOH R 3 .   ? -81.868  -7.125   -26.415 1.00 30.27  ? 1130 HOH F O     1 
HETATM 20747 O O     . HOH R 3 .   ? -67.542  -51.345  -45.180 1.00 48.34  ? 1131 HOH F O     1 
HETATM 20748 O O     . HOH R 3 .   ? -60.272  -41.885  -24.463 1.00 26.36  ? 1132 HOH F O     1 
HETATM 20749 O O     . HOH R 3 .   ? -49.566  -46.010  -28.646 1.00 38.13  ? 1133 HOH F O     1 
HETATM 20750 O O     . HOH R 3 .   ? -67.697  -7.775   -18.492 1.00 28.44  ? 1134 HOH F O     1 
HETATM 20751 O O     . HOH R 3 .   ? -51.216  -34.084  -42.695 1.00 22.58  ? 1135 HOH F O     1 
HETATM 20752 O O     . HOH R 3 .   ? -89.387  -20.147  -13.033 1.00 34.55  ? 1136 HOH F O     1 
HETATM 20753 O O     . HOH R 3 .   ? -52.261  -26.018  -46.893 1.00 21.36  ? 1137 HOH F O     1 
HETATM 20754 O O     . HOH R 3 .   ? -51.546  -26.321  -42.752 1.00 16.11  ? 1138 HOH F O     1 
HETATM 20755 O O     . HOH R 3 .   ? -53.133  -36.615  -21.358 1.00 38.80  ? 1139 HOH F O     1 
HETATM 20756 O O     . HOH R 3 .   ? -72.195  -35.628  -27.564 1.00 27.88  ? 1140 HOH F O     1 
HETATM 20757 O O     . HOH R 3 .   ? -80.640  -12.697  -8.701  1.00 36.57  ? 1141 HOH F O     1 
HETATM 20758 O O     . HOH R 3 .   ? -78.600  -5.388   -24.688 1.00 30.08  ? 1142 HOH F O     1 
HETATM 20759 O O     . HOH R 3 .   ? -51.514  -26.114  -49.866 1.00 17.66  ? 1143 HOH F O     1 
HETATM 20760 O O     . HOH R 3 .   ? -103.692 -20.215  -19.181 1.00 31.47  ? 1144 HOH F O     1 
HETATM 20761 O O     . HOH R 3 .   ? -58.025  -33.203  -21.022 1.00 32.51  ? 1145 HOH F O     1 
HETATM 20762 O O     . HOH R 3 .   ? -72.553  -9.110   -28.564 1.00 33.62  ? 1146 HOH F O     1 
HETATM 20763 O O     . HOH R 3 .   ? -72.926  -32.670  -16.351 1.00 33.16  ? 1147 HOH F O     1 
HETATM 20764 O O     . HOH R 3 .   ? -73.806  -3.274   -17.640 1.00 30.64  ? 1148 HOH F O     1 
HETATM 20765 O O     . HOH R 3 .   ? -60.716  -49.832  -43.004 1.00 30.49  ? 1149 HOH F O     1 
HETATM 20766 O O     . HOH R 3 .   ? -55.326  -17.071  -44.532 1.00 31.15  ? 1150 HOH F O     1 
HETATM 20767 O O     . HOH R 3 .   ? -58.511  -26.703  -59.535 1.00 36.38  ? 1151 HOH F O     1 
HETATM 20768 O O     . HOH R 3 .   ? -40.918  -43.074  -32.576 1.00 39.34  ? 1152 HOH F O     1 
HETATM 20769 O O     . HOH R 3 .   ? -40.432  -46.821  -42.500 1.00 33.79  ? 1153 HOH F O     1 
HETATM 20770 O O     . HOH R 3 .   ? -52.549  -45.352  -44.018 1.00 26.60  ? 1154 HOH F O     1 
HETATM 20771 O O     . HOH R 3 .   ? -56.830  -22.043  -43.552 1.00 30.76  ? 1155 HOH F O     1 
HETATM 20772 O O     . HOH R 3 .   ? -43.713  -45.620  -34.425 1.00 29.74  ? 1156 HOH F O     1 
HETATM 20773 O O     . HOH R 3 .   ? -78.633  -2.832   -19.185 1.00 41.07  ? 1157 HOH F O     1 
HETATM 20774 O O     . HOH R 3 .   ? -99.956  -18.976  -13.766 1.00 39.53  ? 1158 HOH F O     1 
HETATM 20775 O O     . HOH R 3 .   ? -74.795  -12.592  -29.653 1.00 26.41  ? 1159 HOH F O     1 
HETATM 20776 O O     . HOH R 3 .   ? -85.289  -24.265  -5.409  1.00 46.64  ? 1160 HOH F O     1 
HETATM 20777 O O     . HOH R 3 .   ? -80.985  -3.915   -19.045 1.00 33.04  ? 1161 HOH F O     1 
HETATM 20778 O O     . HOH R 3 .   ? -46.542  -22.336  -45.103 1.00 24.27  ? 1162 HOH F O     1 
HETATM 20779 O O     . HOH R 3 .   ? -61.608  -14.072  -19.655 1.00 30.96  ? 1163 HOH F O     1 
HETATM 20780 O O     . HOH R 3 .   ? -63.376  -47.353  -22.304 1.00 39.58  ? 1164 HOH F O     1 
HETATM 20781 O O     . HOH R 3 .   ? -42.608  -46.802  -49.008 1.00 32.23  ? 1165 HOH F O     1 
HETATM 20782 O O     . HOH R 3 .   ? -73.453  -29.986  -23.946 1.00 28.65  ? 1166 HOH F O     1 
HETATM 20783 O O     . HOH R 3 .   ? -66.068  -17.628  -14.811 1.00 34.22  ? 1167 HOH F O     1 
HETATM 20784 O O     . HOH R 3 .   ? -74.686  -7.050   -8.432  1.00 38.20  ? 1168 HOH F O     1 
HETATM 20785 O O     . HOH R 3 .   ? -68.707  -4.733   -14.795 1.00 44.10  ? 1169 HOH F O     1 
HETATM 20786 O O     . HOH R 3 .   ? -86.244  -7.842   -23.917 1.00 33.48  ? 1170 HOH F O     1 
HETATM 20787 O O     . HOH R 3 .   ? -70.864  -13.785  -19.185 1.00 24.36  ? 1171 HOH F O     1 
HETATM 20788 O O     . HOH R 3 .   ? -65.564  -3.165   -19.439 1.00 34.66  ? 1172 HOH F O     1 
HETATM 20789 O O     . HOH R 3 .   ? -53.935  -34.191  -48.116 1.00 26.10  ? 1173 HOH F O     1 
HETATM 20790 O O     . HOH R 3 .   ? -59.462  -53.446  -41.691 1.00 32.81  ? 1174 HOH F O     1 
HETATM 20791 O O     . HOH R 3 .   ? -84.966  -15.303  -24.012 1.00 24.82  ? 1175 HOH F O     1 
HETATM 20792 O O     . HOH R 3 .   ? -66.381  -32.953  -35.757 1.00 42.98  ? 1176 HOH F O     1 
HETATM 20793 O O     . HOH R 3 .   ? -79.409  -20.218  -30.290 1.00 39.62  ? 1177 HOH F O     1 
HETATM 20794 O O     . HOH R 3 .   ? -71.276  0.751    -19.005 1.00 29.99  ? 1178 HOH F O     1 
HETATM 20795 O O     . HOH R 3 .   ? -66.200  -22.965  -43.435 1.00 28.49  ? 1179 HOH F O     1 
HETATM 20796 O O     . HOH R 3 .   ? -66.536  -15.005  -43.462 1.00 33.82  ? 1180 HOH F O     1 
HETATM 20797 O O     . HOH R 3 .   ? -51.301  -13.021  -33.755 1.00 36.49  ? 1181 HOH F O     1 
HETATM 20798 O O     . HOH R 3 .   ? -86.735  -18.830  -28.958 1.00 40.57  ? 1182 HOH F O     1 
HETATM 20799 O O     . HOH R 3 .   ? -42.858  -32.748  -26.529 1.00 38.85  ? 1183 HOH F O     1 
HETATM 20800 O O     . HOH R 3 .   ? -59.057  -57.274  -35.735 1.00 42.65  ? 1184 HOH F O     1 
HETATM 20801 O O     . HOH R 3 .   ? -71.413  -27.282  -21.878 1.00 39.53  ? 1185 HOH F O     1 
HETATM 20802 O O     . HOH R 3 .   ? -58.597  -22.355  -39.631 1.00 31.77  ? 1186 HOH F O     1 
HETATM 20803 O O     . HOH R 3 .   ? -44.816  -28.997  -44.810 1.00 27.86  ? 1187 HOH F O     1 
HETATM 20804 O O     . HOH R 3 .   ? -80.950  -7.295   -13.824 1.00 26.04  ? 1188 HOH F O     1 
HETATM 20805 O O     . HOH R 3 .   ? -67.415  -26.964  -40.683 1.00 40.90  ? 1189 HOH F O     1 
HETATM 20806 O O     . HOH R 3 .   ? -70.588  -33.557  -26.204 1.00 31.03  ? 1190 HOH F O     1 
HETATM 20807 O O     . HOH R 3 .   ? -48.084  -16.219  -39.534 1.00 35.34  ? 1191 HOH F O     1 
HETATM 20808 O O     . HOH R 3 .   ? -77.372  -22.079  -30.337 1.00 42.12  ? 1192 HOH F O     1 
HETATM 20809 O O     . HOH R 3 .   ? -67.902  -26.944  -16.855 1.00 27.24  ? 1193 HOH F O     1 
HETATM 20810 O O     . HOH R 3 .   ? -52.396  -32.073  -51.191 1.00 24.31  ? 1194 HOH F O     1 
HETATM 20811 O O     . HOH R 3 .   ? -77.904  -23.828  -7.200  1.00 44.05  ? 1195 HOH F O     1 
HETATM 20812 O O     . HOH R 3 .   ? -75.942  -9.725   -32.427 1.00 44.84  ? 1196 HOH F O     1 
HETATM 20813 O O     . HOH R 3 .   ? -55.158  -20.055  -43.930 1.00 30.39  ? 1197 HOH F O     1 
HETATM 20814 O O     . HOH R 3 .   ? -67.084  -52.731  -42.179 1.00 34.46  ? 1198 HOH F O     1 
HETATM 20815 O O     . HOH R 3 .   ? -45.231  -24.895  -33.339 1.00 33.62  ? 1199 HOH F O     1 
HETATM 20816 O O     . HOH R 3 .   ? -62.166  -26.426  -48.247 1.00 27.64  ? 1200 HOH F O     1 
HETATM 20817 O O     . HOH R 3 .   ? -61.747  -47.258  -42.591 1.00 25.00  ? 1201 HOH F O     1 
HETATM 20818 O O     . HOH R 3 .   ? -41.497  -28.568  -42.462 1.00 34.25  ? 1202 HOH F O     1 
HETATM 20819 O O     . HOH R 3 .   ? -61.407  -19.766  -15.782 1.00 40.10  ? 1203 HOH F O     1 
HETATM 20820 O O     . HOH R 3 .   ? -81.197  -13.582  -28.434 1.00 27.03  ? 1204 HOH F O     1 
HETATM 20821 O O     . HOH R 3 .   ? -66.043  -24.344  -40.797 1.00 29.33  ? 1205 HOH F O     1 
HETATM 20822 O O     . HOH R 3 .   ? -94.707  -18.443  -8.916  1.00 41.70  ? 1206 HOH F O     1 
HETATM 20823 O O     . HOH R 3 .   ? -46.298  -17.857  -37.300 1.00 41.48  ? 1207 HOH F O     1 
HETATM 20824 O O     . HOH R 3 .   ? -38.882  -29.944  -52.097 1.00 42.95  ? 1208 HOH F O     1 
HETATM 20825 O O     . HOH R 3 .   ? -64.944  -23.464  -49.770 1.00 28.02  ? 1209 HOH F O     1 
HETATM 20826 O O     . HOH R 3 .   ? -56.155  -15.119  -24.470 1.00 42.36  ? 1210 HOH F O     1 
HETATM 20827 O O     . HOH R 3 .   ? -45.697  -38.527  -61.015 1.00 36.30  ? 1211 HOH F O     1 
HETATM 20828 O O     . HOH R 3 .   ? -58.742  -53.570  -55.902 1.00 38.15  ? 1212 HOH F O     1 
HETATM 20829 O O     . HOH R 3 .   ? -40.736  -38.209  -52.309 1.00 43.36  ? 1213 HOH F O     1 
HETATM 20830 O O     . HOH R 3 .   ? -70.151  -27.899  -40.820 1.00 43.91  ? 1214 HOH F O     1 
HETATM 20831 O O     . HOH R 3 .   ? -91.995  -10.233  -15.411 1.00 32.75  ? 1215 HOH F O     1 
HETATM 20832 O O     . HOH R 3 .   ? -73.991  -47.010  -24.239 1.00 42.66  ? 1216 HOH F O     1 
HETATM 20833 O O     . HOH R 3 .   ? -54.231  -45.680  -55.614 1.00 40.56  ? 1217 HOH F O     1 
HETATM 20834 O O     . HOH R 3 .   ? -64.662  -26.104  -15.122 1.00 42.92  ? 1218 HOH F O     1 
HETATM 20835 O O     . HOH R 3 .   ? -79.546  -4.983   -22.186 1.00 28.43  ? 1219 HOH F O     1 
HETATM 20836 O O     . HOH R 3 .   ? -65.043  -24.635  -45.400 1.00 31.03  ? 1220 HOH F O     1 
HETATM 20837 O O     . HOH R 3 .   ? -59.384  -20.253  -21.357 1.00 37.72  ? 1221 HOH F O     1 
HETATM 20838 O O     . HOH R 3 .   ? -73.639  -2.011   -28.485 1.00 39.77  ? 1222 HOH F O     1 
HETATM 20839 O O     . HOH R 3 .   ? -91.931  -14.216  -15.307 1.00 29.65  ? 1223 HOH F O     1 
HETATM 20840 O O     . HOH R 3 .   ? -88.209  -8.719   -9.590  1.00 47.49  ? 1224 HOH F O     1 
HETATM 20841 O O     . HOH R 3 .   ? -51.696  -18.512  -26.790 1.00 35.19  ? 1225 HOH F O     1 
HETATM 20842 O O     . HOH R 3 .   ? -50.309  -54.214  -47.867 1.00 34.50  ? 1226 HOH F O     1 
HETATM 20843 O O     . HOH R 3 .   ? -46.092  -46.101  -49.003 1.00 33.00  ? 1227 HOH F O     1 
HETATM 20844 O O     . HOH R 3 .   ? -69.595  -18.616  -42.027 1.00 38.80  ? 1228 HOH F O     1 
HETATM 20845 O O     . HOH R 3 .   ? -75.269  -20.046  -30.395 1.00 36.84  ? 1229 HOH F O     1 
HETATM 20846 O O     . HOH R 3 .   ? -62.279  -24.528  -50.399 1.00 34.14  ? 1230 HOH F O     1 
HETATM 20847 O O     . HOH R 3 .   ? -86.217  0.559    -19.101 1.00 35.77  ? 1231 HOH F O     1 
HETATM 20848 O O     . HOH R 3 .   ? -41.843  -35.404  -62.860 1.00 47.09  ? 1232 HOH F O     1 
HETATM 20849 O O     . HOH R 3 .   ? -56.568  -23.255  -41.580 1.00 35.30  ? 1233 HOH F O     1 
HETATM 20850 O O     . HOH R 3 .   ? -67.736  -13.961  -47.681 1.00 37.81  ? 1234 HOH F O     1 
HETATM 20851 O O     . HOH R 3 .   ? -45.922  -21.928  -33.181 1.00 35.49  ? 1235 HOH F O     1 
HETATM 20852 O O     . HOH R 3 .   ? -62.123  -40.390  -22.896 1.00 35.67  ? 1236 HOH F O     1 
HETATM 20853 O O     . HOH R 3 .   ? -52.052  -13.113  -31.211 1.00 43.07  ? 1237 HOH F O     1 
HETATM 20854 O O     . HOH R 3 .   ? -58.355  -51.178  -42.582 1.00 37.11  ? 1238 HOH F O     1 
HETATM 20855 O O     . HOH R 3 .   ? -75.316  -32.009  -16.337 1.00 40.67  ? 1239 HOH F O     1 
HETATM 20856 O O     . HOH R 3 .   ? -72.538  -31.566  -13.682 1.00 36.28  ? 1240 HOH F O     1 
HETATM 20857 O O     . HOH R 3 .   ? -84.829  -10.279  -8.401  1.00 41.02  ? 1241 HOH F O     1 
HETATM 20858 O O     . HOH R 3 .   ? -43.041  -22.015  -43.089 1.00 45.40  ? 1242 HOH F O     1 
HETATM 20859 O O     . HOH R 3 .   ? -76.381  -3.323   -11.060 1.00 39.00  ? 1243 HOH F O     1 
HETATM 20860 O O     . HOH R 3 .   ? -50.797  -48.029  -24.303 1.00 40.36  ? 1244 HOH F O     1 
HETATM 20861 O O     . HOH R 3 .   ? -57.184  -11.316  -27.342 1.00 37.25  ? 1245 HOH F O     1 
HETATM 20862 O O     . HOH R 3 .   ? -74.510  -34.554  -24.515 1.00 35.57  ? 1246 HOH F O     1 
HETATM 20863 O O     . HOH R 3 .   ? -45.554  -51.729  -33.988 1.00 34.90  ? 1247 HOH F O     1 
HETATM 20864 O O     . HOH R 3 .   ? -68.788  -22.072  -44.126 1.00 50.27  ? 1248 HOH F O     1 
HETATM 20865 O O     . HOH R 3 .   ? -51.048  -15.507  -40.602 1.00 32.04  ? 1249 HOH F O     1 
HETATM 20866 O O     . HOH R 3 .   ? -43.646  -38.067  -63.217 1.00 39.36  ? 1250 HOH F O     1 
HETATM 20867 O O     . HOH R 3 .   ? -49.096  -48.502  -26.649 1.00 42.71  ? 1251 HOH F O     1 
HETATM 20868 O O     . HOH R 3 .   ? -96.762  -15.871  -16.779 1.00 34.57  ? 1252 HOH F O     1 
HETATM 20869 O O     . HOH R 3 .   ? -64.549  -40.625  -17.195 1.00 51.03  ? 1253 HOH F O     1 
HETATM 20870 O O     . HOH R 3 .   ? -54.230  -11.484  -29.989 1.00 45.06  ? 1254 HOH F O     1 
HETATM 20871 O O     . HOH R 3 .   ? -46.636  -46.617  -51.416 1.00 24.61  ? 1255 HOH F O     1 
HETATM 20872 O O     . HOH R 3 .   ? -72.744  -32.424  -24.441 1.00 32.62  ? 1256 HOH F O     1 
HETATM 20873 O O     . HOH R 3 .   ? -41.757  -42.774  -50.747 1.00 42.54  ? 1257 HOH F O     1 
HETATM 20874 O O     . HOH R 3 .   ? -51.388  -18.846  -29.724 1.00 46.44  ? 1258 HOH F O     1 
HETATM 20875 O O     . HOH R 3 .   ? -42.423  -23.869  -45.395 1.00 44.39  ? 1259 HOH F O     1 
HETATM 20876 O O     . HOH R 3 .   ? -67.452  -17.759  -43.431 1.00 37.53  ? 1260 HOH F O     1 
HETATM 20877 O O     . HOH R 3 .   ? -102.893 -22.018  -20.843 1.00 33.23  ? 1261 HOH F O     1 
HETATM 20878 O O     . HOH R 3 .   ? -64.137  -19.790  -13.722 1.00 41.10  ? 1262 HOH F O     1 
HETATM 20879 O O     . HOH R 3 .   ? -63.357  -30.597  -49.075 1.00 36.76  ? 1263 HOH F O     1 
HETATM 20880 O O     . HOH R 3 .   ? -72.473  -0.912   -17.136 1.00 28.35  ? 1264 HOH F O     1 
HETATM 20881 O O     . HOH R 3 .   ? -51.850  -17.409  -42.288 1.00 31.31  ? 1265 HOH F O     1 
HETATM 20882 O O     . HOH R 3 .   ? -77.376  -33.571  -17.636 1.00 36.49  ? 1266 HOH F O     1 
HETATM 20883 O O     . HOH R 3 .   ? -40.062  -34.888  -26.954 1.00 45.08  ? 1267 HOH F O     1 
# 
