data_9HTA
# 
_entry.id   9HTA 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9HTA         pdb_00009hta 10.2210/pdb9hta/pdb 
WWPDB D_1292144107 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-12 ? 
2 'Structure model' 1 1 2025-03-19 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation_author.identifier_ORCID' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9HTA 
_pdbx_database_status.recvd_initial_deposition_date   2024-12-19 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        PDB 
_pdbx_database_related.details        'same protein complexed with 6-ACETAMIDO-6-DEOXY-CASTANOSPERMINE' 
_pdbx_database_related.db_id          8QB6 
_pdbx_database_related.content_type   unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              gideon.davies@york.ac.uk 
_pdbx_contact_author.name_first         Gideon 
_pdbx_contact_author.name_last          Davies 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7343-776X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Males, A.'            1  ?                   
'Moroz, O.V.'          2  0000-0002-0354-6119 
'Blagova, E.'          3  ?                   
'Munch, A.'            4  ?                   
'Hansen, G.H.'         5  ?                   
'Johansen, A.H.'       6  ?                   
'Ostergaard, L.H.'     7  ?                   
'Segura, D.R.'         8  ?                   
'Eddenden, A.'         9  ?                   
'Due, A.V.'            10 ?                   
'Gudmand, M.'          11 ?                   
'Salomon, J.'          12 ?                   
'Sorensen, S.R.'       13 ?                   
'Franco Cairo, J.P.L.' 14 ?                   
'Pache, R.A.'          15 ?                   
'Vejborg, R.M.'        16 ?                   
'Bhosale, S.'          17 ?                   
'Vocadlo, D.'          18 ?                   
'Davies, G.J.'         19 ?                   
'Wilson, K.S.'         20 ?                   
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Acta Crystallogr D Struct Biol' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2059-7983 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            81 
_citation.language                  ? 
_citation.page_first                130 
_citation.page_last                 146 
_citation.title                     'Expansion of the diversity of dispersin scaffolds.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1107/S205979832500110X 
_citation.pdbx_database_id_PubMed   40019001 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Males, A.'            1  ? 
primary 'Moroz, O.V.'          2  ? 
primary 'Blagova, E.'          3  ? 
primary 'Munch, A.'            4  ? 
primary 'Hansen, G.H.'         5  ? 
primary 'Johansen, A.H.'       6  ? 
primary 'Ostergaard, L.H.'     7  ? 
primary 'Segura, D.R.'         8  ? 
primary 'Eddenden, A.'         9  ? 
primary 'Due, A.V.'            10 ? 
primary 'Gudmand, M.'          11 ? 
primary 'Salomon, J.'          12 ? 
primary 'Sorensen, S.R.'       13 ? 
primary 'Franco Cairo, J.P.L.' 14 ? 
primary 'Nitz, M.'             15 ? 
primary 'Pache, R.A.'          16 ? 
primary 'Vejborg, R.M.'        17 ? 
primary 'Bhosale, S.'          18 ? 
primary 'Vocadlo, D.J.'        19 ? 
primary 'Davies, G.J.'         20 ? 
primary 'Wilson, K.S.'         21 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Dispersin                                                                                          37562.176 1  
? ? ? ? 
2 non-polymer syn '3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL' 219.258   1  
? ? ? ? 
3 water       nat water                                                                                              18.015    43 
? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;QDQEKGITIDISRKHYTVETLKSLVDEISYNGGNYVQLHFSDNENYAIASEYLGQSSENTNNTYLTKNELLSLIAYSNDK
DILVIPDIDLPAHSKGWLELIKKKDVKLYNDIVTDYSEETLDYYDNRVALDTVNQLLDEVLDLFYQPKFEGKQRIVLGGD
EVSGSEVHQLDFIDFMNQIASTVKESKYEPQMWNDSITSEGIANLDDSFSILYWQQSTLSSGEESLNVEDFENWGFSVYN
YNAYSLYFLPSNGFTQEDINEQMDYMNWAYAHNKFFYISDYYHAVETSNVKGSSLTFWGEHATDLSQKKLLKQELPLIRH
YLNL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;QDQEKGITIDISRKHYTVETLKSLVDEISYNGGNYVQLHFSDNENYAIASEYLGQSSENTNNTYLTKNELLSLIAYSNDK
DILVIPDIDLPAHSKGWLELIKKKDVKLYNDIVTDYSEETLDYYDNRVALDTVNQLLDEVLDLFYQPKFEGKQRIVLGGD
EVSGSEVHQLDFIDFMNQIASTVKESKYEPQMWNDSITSEGIANLDDSFSILYWQQSTLSSGEESLNVEDFENWGFSVYN
YNAYSLYFLPSNGFTQEDINEQMDYMNWAYAHNKFFYISDYYHAVETSNVKGSSLTFWGEHATDLSQKKLLKQELPLIRH
YLNL
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL' NGT 
3 water                                                                                              HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLN n 
1 2   ASP n 
1 3   GLN n 
1 4   GLU n 
1 5   LYS n 
1 6   GLY n 
1 7   ILE n 
1 8   THR n 
1 9   ILE n 
1 10  ASP n 
1 11  ILE n 
1 12  SER n 
1 13  ARG n 
1 14  LYS n 
1 15  HIS n 
1 16  TYR n 
1 17  THR n 
1 18  VAL n 
1 19  GLU n 
1 20  THR n 
1 21  LEU n 
1 22  LYS n 
1 23  SER n 
1 24  LEU n 
1 25  VAL n 
1 26  ASP n 
1 27  GLU n 
1 28  ILE n 
1 29  SER n 
1 30  TYR n 
1 31  ASN n 
1 32  GLY n 
1 33  GLY n 
1 34  ASN n 
1 35  TYR n 
1 36  VAL n 
1 37  GLN n 
1 38  LEU n 
1 39  HIS n 
1 40  PHE n 
1 41  SER n 
1 42  ASP n 
1 43  ASN n 
1 44  GLU n 
1 45  ASN n 
1 46  TYR n 
1 47  ALA n 
1 48  ILE n 
1 49  ALA n 
1 50  SER n 
1 51  GLU n 
1 52  TYR n 
1 53  LEU n 
1 54  GLY n 
1 55  GLN n 
1 56  SER n 
1 57  SER n 
1 58  GLU n 
1 59  ASN n 
1 60  THR n 
1 61  ASN n 
1 62  ASN n 
1 63  THR n 
1 64  TYR n 
1 65  LEU n 
1 66  THR n 
1 67  LYS n 
1 68  ASN n 
1 69  GLU n 
1 70  LEU n 
1 71  LEU n 
1 72  SER n 
1 73  LEU n 
1 74  ILE n 
1 75  ALA n 
1 76  TYR n 
1 77  SER n 
1 78  ASN n 
1 79  ASP n 
1 80  LYS n 
1 81  ASP n 
1 82  ILE n 
1 83  LEU n 
1 84  VAL n 
1 85  ILE n 
1 86  PRO n 
1 87  ASP n 
1 88  ILE n 
1 89  ASP n 
1 90  LEU n 
1 91  PRO n 
1 92  ALA n 
1 93  HIS n 
1 94  SER n 
1 95  LYS n 
1 96  GLY n 
1 97  TRP n 
1 98  LEU n 
1 99  GLU n 
1 100 LEU n 
1 101 ILE n 
1 102 LYS n 
1 103 LYS n 
1 104 LYS n 
1 105 ASP n 
1 106 VAL n 
1 107 LYS n 
1 108 LEU n 
1 109 TYR n 
1 110 ASN n 
1 111 ASP n 
1 112 ILE n 
1 113 VAL n 
1 114 THR n 
1 115 ASP n 
1 116 TYR n 
1 117 SER n 
1 118 GLU n 
1 119 GLU n 
1 120 THR n 
1 121 LEU n 
1 122 ASP n 
1 123 TYR n 
1 124 TYR n 
1 125 ASP n 
1 126 ASN n 
1 127 ARG n 
1 128 VAL n 
1 129 ALA n 
1 130 LEU n 
1 131 ASP n 
1 132 THR n 
1 133 VAL n 
1 134 ASN n 
1 135 GLN n 
1 136 LEU n 
1 137 LEU n 
1 138 ASP n 
1 139 GLU n 
1 140 VAL n 
1 141 LEU n 
1 142 ASP n 
1 143 LEU n 
1 144 PHE n 
1 145 TYR n 
1 146 GLN n 
1 147 PRO n 
1 148 LYS n 
1 149 PHE n 
1 150 GLU n 
1 151 GLY n 
1 152 LYS n 
1 153 GLN n 
1 154 ARG n 
1 155 ILE n 
1 156 VAL n 
1 157 LEU n 
1 158 GLY n 
1 159 GLY n 
1 160 ASP n 
1 161 GLU n 
1 162 VAL n 
1 163 SER n 
1 164 GLY n 
1 165 SER n 
1 166 GLU n 
1 167 VAL n 
1 168 HIS n 
1 169 GLN n 
1 170 LEU n 
1 171 ASP n 
1 172 PHE n 
1 173 ILE n 
1 174 ASP n 
1 175 PHE n 
1 176 MET n 
1 177 ASN n 
1 178 GLN n 
1 179 ILE n 
1 180 ALA n 
1 181 SER n 
1 182 THR n 
1 183 VAL n 
1 184 LYS n 
1 185 GLU n 
1 186 SER n 
1 187 LYS n 
1 188 TYR n 
1 189 GLU n 
1 190 PRO n 
1 191 GLN n 
1 192 MET n 
1 193 TRP n 
1 194 ASN n 
1 195 ASP n 
1 196 SER n 
1 197 ILE n 
1 198 THR n 
1 199 SER n 
1 200 GLU n 
1 201 GLY n 
1 202 ILE n 
1 203 ALA n 
1 204 ASN n 
1 205 LEU n 
1 206 ASP n 
1 207 ASP n 
1 208 SER n 
1 209 PHE n 
1 210 SER n 
1 211 ILE n 
1 212 LEU n 
1 213 TYR n 
1 214 TRP n 
1 215 GLN n 
1 216 GLN n 
1 217 SER n 
1 218 THR n 
1 219 LEU n 
1 220 SER n 
1 221 SER n 
1 222 GLY n 
1 223 GLU n 
1 224 GLU n 
1 225 SER n 
1 226 LEU n 
1 227 ASN n 
1 228 VAL n 
1 229 GLU n 
1 230 ASP n 
1 231 PHE n 
1 232 GLU n 
1 233 ASN n 
1 234 TRP n 
1 235 GLY n 
1 236 PHE n 
1 237 SER n 
1 238 VAL n 
1 239 TYR n 
1 240 ASN n 
1 241 TYR n 
1 242 ASN n 
1 243 ALA n 
1 244 TYR n 
1 245 SER n 
1 246 LEU n 
1 247 TYR n 
1 248 PHE n 
1 249 LEU n 
1 250 PRO n 
1 251 SER n 
1 252 ASN n 
1 253 GLY n 
1 254 PHE n 
1 255 THR n 
1 256 GLN n 
1 257 GLU n 
1 258 ASP n 
1 259 ILE n 
1 260 ASN n 
1 261 GLU n 
1 262 GLN n 
1 263 MET n 
1 264 ASP n 
1 265 TYR n 
1 266 MET n 
1 267 ASN n 
1 268 TRP n 
1 269 ALA n 
1 270 TYR n 
1 271 ALA n 
1 272 HIS n 
1 273 ASN n 
1 274 LYS n 
1 275 PHE n 
1 276 PHE n 
1 277 TYR n 
1 278 ILE n 
1 279 SER n 
1 280 ASP n 
1 281 TYR n 
1 282 TYR n 
1 283 HIS n 
1 284 ALA n 
1 285 VAL n 
1 286 GLU n 
1 287 THR n 
1 288 SER n 
1 289 ASN n 
1 290 VAL n 
1 291 LYS n 
1 292 GLY n 
1 293 SER n 
1 294 SER n 
1 295 LEU n 
1 296 THR n 
1 297 PHE n 
1 298 TRP n 
1 299 GLY n 
1 300 GLU n 
1 301 HIS n 
1 302 ALA n 
1 303 THR n 
1 304 ASP n 
1 305 LEU n 
1 306 SER n 
1 307 GLN n 
1 308 LYS n 
1 309 LYS n 
1 310 LEU n 
1 311 LEU n 
1 312 LYS n 
1 313 GLN n 
1 314 GLU n 
1 315 LEU n 
1 316 PRO n 
1 317 LEU n 
1 318 ILE n 
1 319 ARG n 
1 320 HIS n 
1 321 TYR n 
1 322 LEU n 
1 323 ASN n 
1 324 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   324 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Terribacillus saccharophilus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     361277 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Bacillus subtilis' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     1423 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                                                                            ? 
'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                                                                           ? 
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                                                         ? 
'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                                                    ? 
'C4 H7 N O4'     133.103 
GLN 'L-peptide linking' y GLUTAMINE                                                                                          ? 
'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                                                    ? 
'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                                                                            ? 
'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                                                                          ? 
'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                                                                                              ? 
'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                                                                         ? 
'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                                                                            ? 
'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                                                                             ? 
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                                                                         ? 
'C5 H11 N O2 S'  149.211 
NGT non-polymer         . '3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL' ? 
'C8 H13 N O4 S'  219.258 
PHE 'L-peptide linking' y PHENYLALANINE                                                                                      ? 
'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                                                                            ? 
'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                                                                             ? 
'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                                                                          ? 
'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                                                         ? 
'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                                                                           ? 
'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                                                                             ? 
'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLN 1   1   ?   ?   ?   A . n 
A 1 2   ASP 2   2   2   ASP ASP A . n 
A 1 3   GLN 3   3   3   GLN GLN A . n 
A 1 4   GLU 4   4   4   GLU GLU A . n 
A 1 5   LYS 5   5   5   LYS LYS A . n 
A 1 6   GLY 6   6   6   GLY GLY A . n 
A 1 7   ILE 7   7   7   ILE ILE A . n 
A 1 8   THR 8   8   8   THR THR A . n 
A 1 9   ILE 9   9   9   ILE ILE A . n 
A 1 10  ASP 10  10  10  ASP ASP A . n 
A 1 11  ILE 11  11  11  ILE ILE A . n 
A 1 12  SER 12  12  12  SER SER A . n 
A 1 13  ARG 13  13  13  ARG ARG A . n 
A 1 14  LYS 14  14  14  LYS LYS A . n 
A 1 15  HIS 15  15  15  HIS HIS A . n 
A 1 16  TYR 16  16  16  TYR TYR A . n 
A 1 17  THR 17  17  17  THR THR A . n 
A 1 18  VAL 18  18  18  VAL VAL A . n 
A 1 19  GLU 19  19  19  GLU GLU A . n 
A 1 20  THR 20  20  20  THR THR A . n 
A 1 21  LEU 21  21  21  LEU LEU A . n 
A 1 22  LYS 22  22  22  LYS LYS A . n 
A 1 23  SER 23  23  23  SER SER A . n 
A 1 24  LEU 24  24  24  LEU LEU A . n 
A 1 25  VAL 25  25  25  VAL VAL A . n 
A 1 26  ASP 26  26  26  ASP ASP A . n 
A 1 27  GLU 27  27  27  GLU GLU A . n 
A 1 28  ILE 28  28  28  ILE ILE A . n 
A 1 29  SER 29  29  29  SER SER A . n 
A 1 30  TYR 30  30  30  TYR TYR A . n 
A 1 31  ASN 31  31  31  ASN ASN A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  GLY 33  33  33  GLY GLY A . n 
A 1 34  ASN 34  34  34  ASN ASN A . n 
A 1 35  TYR 35  35  35  TYR TYR A . n 
A 1 36  VAL 36  36  36  VAL VAL A . n 
A 1 37  GLN 37  37  37  GLN GLN A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  HIS 39  39  39  HIS HIS A . n 
A 1 40  PHE 40  40  40  PHE PHE A . n 
A 1 41  SER 41  41  41  SER SER A . n 
A 1 42  ASP 42  42  42  ASP ASP A . n 
A 1 43  ASN 43  43  43  ASN ASN A . n 
A 1 44  GLU 44  44  44  GLU GLU A . n 
A 1 45  ASN 45  45  45  ASN ASN A . n 
A 1 46  TYR 46  46  46  TYR TYR A . n 
A 1 47  ALA 47  47  47  ALA ALA A . n 
A 1 48  ILE 48  48  48  ILE ILE A . n 
A 1 49  ALA 49  49  49  ALA ALA A . n 
A 1 50  SER 50  50  50  SER SER A . n 
A 1 51  GLU 51  51  51  GLU GLU A . n 
A 1 52  TYR 52  52  52  TYR TYR A . n 
A 1 53  LEU 53  53  53  LEU LEU A . n 
A 1 54  GLY 54  54  54  GLY GLY A . n 
A 1 55  GLN 55  55  55  GLN GLN A . n 
A 1 56  SER 56  56  56  SER SER A . n 
A 1 57  SER 57  57  57  SER SER A . n 
A 1 58  GLU 58  58  58  GLU GLU A . n 
A 1 59  ASN 59  59  59  ASN ASN A . n 
A 1 60  THR 60  60  60  THR THR A . n 
A 1 61  ASN 61  61  61  ASN ASN A . n 
A 1 62  ASN 62  62  62  ASN ASN A . n 
A 1 63  THR 63  63  63  THR THR A . n 
A 1 64  TYR 64  64  64  TYR TYR A . n 
A 1 65  LEU 65  65  65  LEU LEU A . n 
A 1 66  THR 66  66  66  THR THR A . n 
A 1 67  LYS 67  67  67  LYS LYS A . n 
A 1 68  ASN 68  68  68  ASN ASN A . n 
A 1 69  GLU 69  69  69  GLU GLU A . n 
A 1 70  LEU 70  70  70  LEU LEU A . n 
A 1 71  LEU 71  71  71  LEU LEU A . n 
A 1 72  SER 72  72  72  SER SER A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  ILE 74  74  74  ILE ILE A . n 
A 1 75  ALA 75  75  75  ALA ALA A . n 
A 1 76  TYR 76  76  76  TYR TYR A . n 
A 1 77  SER 77  77  77  SER SER A . n 
A 1 78  ASN 78  78  78  ASN ASN A . n 
A 1 79  ASP 79  79  79  ASP ASP A . n 
A 1 80  LYS 80  80  80  LYS LYS A . n 
A 1 81  ASP 81  81  81  ASP ASP A . n 
A 1 82  ILE 82  82  82  ILE ILE A . n 
A 1 83  LEU 83  83  83  LEU LEU A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  ILE 85  85  85  ILE ILE A . n 
A 1 86  PRO 86  86  86  PRO PRO A . n 
A 1 87  ASP 87  87  87  ASP ASP A . n 
A 1 88  ILE 88  88  88  ILE ILE A . n 
A 1 89  ASP 89  89  89  ASP ASP A . n 
A 1 90  LEU 90  90  90  LEU LEU A . n 
A 1 91  PRO 91  91  91  PRO PRO A . n 
A 1 92  ALA 92  92  92  ALA ALA A . n 
A 1 93  HIS 93  93  93  HIS HIS A . n 
A 1 94  SER 94  94  94  SER SER A . n 
A 1 95  LYS 95  95  95  LYS LYS A . n 
A 1 96  GLY 96  96  96  GLY GLY A . n 
A 1 97  TRP 97  97  97  TRP TRP A . n 
A 1 98  LEU 98  98  98  LEU LEU A . n 
A 1 99  GLU 99  99  99  GLU GLU A . n 
A 1 100 LEU 100 100 100 LEU LEU A . n 
A 1 101 ILE 101 101 101 ILE ILE A . n 
A 1 102 LYS 102 102 102 LYS LYS A . n 
A 1 103 LYS 103 103 103 LYS LYS A . n 
A 1 104 LYS 104 104 104 LYS LYS A . n 
A 1 105 ASP 105 105 105 ASP ASP A . n 
A 1 106 VAL 106 106 106 VAL VAL A . n 
A 1 107 LYS 107 107 107 LYS LYS A . n 
A 1 108 LEU 108 108 108 LEU LEU A . n 
A 1 109 TYR 109 109 109 TYR TYR A . n 
A 1 110 ASN 110 110 110 ASN ASN A . n 
A 1 111 ASP 111 111 111 ASP ASP A . n 
A 1 112 ILE 112 112 112 ILE ILE A . n 
A 1 113 VAL 113 113 113 VAL VAL A . n 
A 1 114 THR 114 114 114 THR THR A . n 
A 1 115 ASP 115 115 115 ASP ASP A . n 
A 1 116 TYR 116 116 116 TYR TYR A . n 
A 1 117 SER 117 117 117 SER SER A . n 
A 1 118 GLU 118 118 118 GLU GLU A . n 
A 1 119 GLU 119 119 119 GLU GLU A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 LEU 121 121 121 LEU LEU A . n 
A 1 122 ASP 122 122 122 ASP ASP A . n 
A 1 123 TYR 123 123 123 TYR TYR A . n 
A 1 124 TYR 124 124 124 TYR TYR A . n 
A 1 125 ASP 125 125 125 ASP ASP A . n 
A 1 126 ASN 126 126 126 ASN ASN A . n 
A 1 127 ARG 127 127 127 ARG ARG A . n 
A 1 128 VAL 128 128 128 VAL VAL A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 LEU 130 130 130 LEU LEU A . n 
A 1 131 ASP 131 131 131 ASP ASP A . n 
A 1 132 THR 132 132 132 THR THR A . n 
A 1 133 VAL 133 133 133 VAL VAL A . n 
A 1 134 ASN 134 134 134 ASN ASN A . n 
A 1 135 GLN 135 135 135 GLN GLN A . n 
A 1 136 LEU 136 136 136 LEU LEU A . n 
A 1 137 LEU 137 137 137 LEU LEU A . n 
A 1 138 ASP 138 138 138 ASP ASP A . n 
A 1 139 GLU 139 139 139 GLU GLU A . n 
A 1 140 VAL 140 140 140 VAL VAL A . n 
A 1 141 LEU 141 141 141 LEU LEU A . n 
A 1 142 ASP 142 142 142 ASP ASP A . n 
A 1 143 LEU 143 143 143 LEU LEU A . n 
A 1 144 PHE 144 144 144 PHE PHE A . n 
A 1 145 TYR 145 145 145 TYR TYR A . n 
A 1 146 GLN 146 146 146 GLN GLN A . n 
A 1 147 PRO 147 147 147 PRO PRO A . n 
A 1 148 LYS 148 148 148 LYS LYS A . n 
A 1 149 PHE 149 149 149 PHE PHE A . n 
A 1 150 GLU 150 150 150 GLU GLU A . n 
A 1 151 GLY 151 151 151 GLY GLY A . n 
A 1 152 LYS 152 152 152 LYS LYS A . n 
A 1 153 GLN 153 153 153 GLN GLN A . n 
A 1 154 ARG 154 154 154 ARG ARG A . n 
A 1 155 ILE 155 155 155 ILE ILE A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 LEU 157 157 157 LEU LEU A . n 
A 1 158 GLY 158 158 158 GLY GLY A . n 
A 1 159 GLY 159 159 159 GLY GLY A . n 
A 1 160 ASP 160 160 160 ASP ASP A . n 
A 1 161 GLU 161 161 161 GLU GLU A . n 
A 1 162 VAL 162 162 162 VAL VAL A . n 
A 1 163 SER 163 163 163 SER SER A . n 
A 1 164 GLY 164 164 164 GLY GLY A . n 
A 1 165 SER 165 165 165 SER SER A . n 
A 1 166 GLU 166 166 166 GLU GLU A . n 
A 1 167 VAL 167 167 167 VAL VAL A . n 
A 1 168 HIS 168 168 168 HIS HIS A . n 
A 1 169 GLN 169 169 169 GLN GLN A . n 
A 1 170 LEU 170 170 170 LEU LEU A . n 
A 1 171 ASP 171 171 171 ASP ASP A . n 
A 1 172 PHE 172 172 172 PHE PHE A . n 
A 1 173 ILE 173 173 173 ILE ILE A . n 
A 1 174 ASP 174 174 174 ASP ASP A . n 
A 1 175 PHE 175 175 175 PHE PHE A . n 
A 1 176 MET 176 176 176 MET MET A . n 
A 1 177 ASN 177 177 177 ASN ASN A . n 
A 1 178 GLN 178 178 178 GLN GLN A . n 
A 1 179 ILE 179 179 179 ILE ILE A . n 
A 1 180 ALA 180 180 180 ALA ALA A . n 
A 1 181 SER 181 181 181 SER SER A . n 
A 1 182 THR 182 182 182 THR THR A . n 
A 1 183 VAL 183 183 183 VAL VAL A . n 
A 1 184 LYS 184 184 184 LYS LYS A . n 
A 1 185 GLU 185 185 185 GLU GLU A . n 
A 1 186 SER 186 186 186 SER SER A . n 
A 1 187 LYS 187 187 187 LYS LYS A . n 
A 1 188 TYR 188 188 188 TYR TYR A . n 
A 1 189 GLU 189 189 189 GLU GLU A . n 
A 1 190 PRO 190 190 190 PRO PRO A . n 
A 1 191 GLN 191 191 191 GLN GLN A . n 
A 1 192 MET 192 192 192 MET MET A . n 
A 1 193 TRP 193 193 193 TRP TRP A . n 
A 1 194 ASN 194 194 194 ASN ASN A . n 
A 1 195 ASP 195 195 195 ASP ASP A . n 
A 1 196 SER 196 196 196 SER SER A . n 
A 1 197 ILE 197 197 197 ILE ILE A . n 
A 1 198 THR 198 198 198 THR THR A . n 
A 1 199 SER 199 199 199 SER SER A . n 
A 1 200 GLU 200 200 200 GLU GLU A . n 
A 1 201 GLY 201 201 201 GLY GLY A . n 
A 1 202 ILE 202 202 202 ILE ILE A . n 
A 1 203 ALA 203 203 203 ALA ALA A . n 
A 1 204 ASN 204 204 204 ASN ASN A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 ASP 206 206 206 ASP ASP A . n 
A 1 207 ASP 207 207 207 ASP ASP A . n 
A 1 208 SER 208 208 208 SER SER A . n 
A 1 209 PHE 209 209 209 PHE PHE A . n 
A 1 210 SER 210 210 210 SER SER A . n 
A 1 211 ILE 211 211 211 ILE ILE A . n 
A 1 212 LEU 212 212 212 LEU LEU A . n 
A 1 213 TYR 213 213 213 TYR TYR A . n 
A 1 214 TRP 214 214 214 TRP TRP A . n 
A 1 215 GLN 215 215 215 GLN GLN A . n 
A 1 216 GLN 216 216 216 GLN GLN A . n 
A 1 217 SER 217 217 217 SER SER A . n 
A 1 218 THR 218 218 218 THR THR A . n 
A 1 219 LEU 219 219 219 LEU LEU A . n 
A 1 220 SER 220 220 220 SER SER A . n 
A 1 221 SER 221 221 221 SER SER A . n 
A 1 222 GLY 222 222 222 GLY GLY A . n 
A 1 223 GLU 223 223 223 GLU GLU A . n 
A 1 224 GLU 224 224 224 GLU GLU A . n 
A 1 225 SER 225 225 225 SER SER A . n 
A 1 226 LEU 226 226 226 LEU LEU A . n 
A 1 227 ASN 227 227 227 ASN ASN A . n 
A 1 228 VAL 228 228 228 VAL VAL A . n 
A 1 229 GLU 229 229 229 GLU GLU A . n 
A 1 230 ASP 230 230 230 ASP ASP A . n 
A 1 231 PHE 231 231 231 PHE PHE A . n 
A 1 232 GLU 232 232 232 GLU GLU A . n 
A 1 233 ASN 233 233 233 ASN ASN A . n 
A 1 234 TRP 234 234 234 TRP TRP A . n 
A 1 235 GLY 235 235 235 GLY GLY A . n 
A 1 236 PHE 236 236 236 PHE PHE A . n 
A 1 237 SER 237 237 237 SER SER A . n 
A 1 238 VAL 238 238 238 VAL VAL A . n 
A 1 239 TYR 239 239 239 TYR TYR A . n 
A 1 240 ASN 240 240 240 ASN ASN A . n 
A 1 241 TYR 241 241 241 TYR TYR A . n 
A 1 242 ASN 242 242 242 ASN ASN A . n 
A 1 243 ALA 243 243 243 ALA ALA A . n 
A 1 244 TYR 244 244 244 TYR TYR A . n 
A 1 245 SER 245 245 245 SER SER A . n 
A 1 246 LEU 246 246 246 LEU LEU A . n 
A 1 247 TYR 247 247 247 TYR TYR A . n 
A 1 248 PHE 248 248 248 PHE PHE A . n 
A 1 249 LEU 249 249 249 LEU LEU A . n 
A 1 250 PRO 250 250 250 PRO PRO A . n 
A 1 251 SER 251 251 251 SER SER A . n 
A 1 252 ASN 252 252 252 ASN ASN A . n 
A 1 253 GLY 253 253 253 GLY GLY A . n 
A 1 254 PHE 254 254 254 PHE PHE A . n 
A 1 255 THR 255 255 255 THR THR A . n 
A 1 256 GLN 256 256 256 GLN GLN A . n 
A 1 257 GLU 257 257 257 GLU GLU A . n 
A 1 258 ASP 258 258 258 ASP ASP A . n 
A 1 259 ILE 259 259 259 ILE ILE A . n 
A 1 260 ASN 260 260 260 ASN ASN A . n 
A 1 261 GLU 261 261 261 GLU GLU A . n 
A 1 262 GLN 262 262 262 GLN GLN A . n 
A 1 263 MET 263 263 263 MET MET A . n 
A 1 264 ASP 264 264 264 ASP ASP A . n 
A 1 265 TYR 265 265 265 TYR TYR A . n 
A 1 266 MET 266 266 266 MET MET A . n 
A 1 267 ASN 267 267 267 ASN ASN A . n 
A 1 268 TRP 268 268 268 TRP TRP A . n 
A 1 269 ALA 269 269 269 ALA ALA A . n 
A 1 270 TYR 270 270 270 TYR TYR A . n 
A 1 271 ALA 271 271 271 ALA ALA A . n 
A 1 272 HIS 272 272 272 HIS HIS A . n 
A 1 273 ASN 273 273 273 ASN ASN A . n 
A 1 274 LYS 274 274 274 LYS LYS A . n 
A 1 275 PHE 275 275 275 PHE PHE A . n 
A 1 276 PHE 276 276 276 PHE PHE A . n 
A 1 277 TYR 277 277 277 TYR TYR A . n 
A 1 278 ILE 278 278 278 ILE ILE A . n 
A 1 279 SER 279 279 279 SER SER A . n 
A 1 280 ASP 280 280 280 ASP ASP A . n 
A 1 281 TYR 281 281 281 TYR TYR A . n 
A 1 282 TYR 282 282 282 TYR TYR A . n 
A 1 283 HIS 283 283 283 HIS HIS A . n 
A 1 284 ALA 284 284 284 ALA ALA A . n 
A 1 285 VAL 285 285 285 VAL VAL A . n 
A 1 286 GLU 286 286 286 GLU GLU A . n 
A 1 287 THR 287 287 287 THR THR A . n 
A 1 288 SER 288 288 288 SER SER A . n 
A 1 289 ASN 289 289 289 ASN ASN A . n 
A 1 290 VAL 290 290 290 VAL VAL A . n 
A 1 291 LYS 291 291 291 LYS LYS A . n 
A 1 292 GLY 292 292 292 GLY GLY A . n 
A 1 293 SER 293 293 293 SER SER A . n 
A 1 294 SER 294 294 294 SER SER A . n 
A 1 295 LEU 295 295 295 LEU LEU A . n 
A 1 296 THR 296 296 296 THR THR A . n 
A 1 297 PHE 297 297 297 PHE PHE A . n 
A 1 298 TRP 298 298 298 TRP TRP A . n 
A 1 299 GLY 299 299 299 GLY GLY A . n 
A 1 300 GLU 300 300 300 GLU GLU A . n 
A 1 301 HIS 301 301 301 HIS HIS A . n 
A 1 302 ALA 302 302 302 ALA ALA A . n 
A 1 303 THR 303 303 303 THR THR A . n 
A 1 304 ASP 304 304 304 ASP ASP A . n 
A 1 305 LEU 305 305 305 LEU LEU A . n 
A 1 306 SER 306 306 306 SER SER A . n 
A 1 307 GLN 307 307 307 GLN GLN A . n 
A 1 308 LYS 308 308 308 LYS LYS A . n 
A 1 309 LYS 309 309 309 LYS LYS A . n 
A 1 310 LEU 310 310 310 LEU LEU A . n 
A 1 311 LEU 311 311 311 LEU LEU A . n 
A 1 312 LYS 312 312 312 LYS LYS A . n 
A 1 313 GLN 313 313 313 GLN GLN A . n 
A 1 314 GLU 314 314 314 GLU GLU A . n 
A 1 315 LEU 315 315 315 LEU LEU A . n 
A 1 316 PRO 316 316 316 PRO PRO A . n 
A 1 317 LEU 317 317 317 LEU LEU A . n 
A 1 318 ILE 318 318 318 ILE ILE A . n 
A 1 319 ARG 319 319 319 ARG ARG A . n 
A 1 320 HIS 320 320 320 HIS HIS A . n 
A 1 321 TYR 321 321 321 TYR TYR A . n 
A 1 322 LEU 322 322 322 LEU LEU A . n 
A 1 323 ASN 323 323 323 ASN ASN A . n 
A 1 324 LEU 324 324 324 LEU LEU A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        NGT 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   NGT 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 NGT 1  401 401 NGT NGT A . 
C 3 HOH 1  501 9   HOH HOH A . 
C 3 HOH 2  502 39  HOH HOH A . 
C 3 HOH 3  503 17  HOH HOH A . 
C 3 HOH 4  504 12  HOH HOH A . 
C 3 HOH 5  505 2   HOH HOH A . 
C 3 HOH 6  506 7   HOH HOH A . 
C 3 HOH 7  507 37  HOH HOH A . 
C 3 HOH 8  508 23  HOH HOH A . 
C 3 HOH 9  509 38  HOH HOH A . 
C 3 HOH 10 510 5   HOH HOH A . 
C 3 HOH 11 511 40  HOH HOH A . 
C 3 HOH 12 512 6   HOH HOH A . 
C 3 HOH 13 513 14  HOH HOH A . 
C 3 HOH 14 514 36  HOH HOH A . 
C 3 HOH 15 515 16  HOH HOH A . 
C 3 HOH 16 516 11  HOH HOH A . 
C 3 HOH 17 517 8   HOH HOH A . 
C 3 HOH 18 518 42  HOH HOH A . 
C 3 HOH 19 519 19  HOH HOH A . 
C 3 HOH 20 520 32  HOH HOH A . 
C 3 HOH 21 521 20  HOH HOH A . 
C 3 HOH 22 522 4   HOH HOH A . 
C 3 HOH 23 523 13  HOH HOH A . 
C 3 HOH 24 524 34  HOH HOH A . 
C 3 HOH 25 525 3   HOH HOH A . 
C 3 HOH 26 526 10  HOH HOH A . 
C 3 HOH 27 527 41  HOH HOH A . 
C 3 HOH 28 528 1   HOH HOH A . 
C 3 HOH 29 529 25  HOH HOH A . 
C 3 HOH 30 530 21  HOH HOH A . 
C 3 HOH 31 531 35  HOH HOH A . 
C 3 HOH 32 532 26  HOH HOH A . 
C 3 HOH 33 533 33  HOH HOH A . 
C 3 HOH 34 534 22  HOH HOH A . 
C 3 HOH 35 535 30  HOH HOH A . 
C 3 HOH 36 536 31  HOH HOH A . 
C 3 HOH 37 537 29  HOH HOH A . 
C 3 HOH 38 538 15  HOH HOH A . 
C 3 HOH 39 539 18  HOH HOH A . 
C 3 HOH 40 540 24  HOH HOH A . 
C 3 HOH 41 541 27  HOH HOH A . 
C 3 HOH 42 542 28  HOH HOH A . 
C 3 HOH 43 543 43  HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLU 58  ? CG  ? A GLU 58  CG  
2  1 Y 1 A GLU 58  ? CD  ? A GLU 58  CD  
3  1 Y 1 A GLU 58  ? OE1 ? A GLU 58  OE1 
4  1 Y 1 A GLU 58  ? OE2 ? A GLU 58  OE2 
5  1 Y 1 A LYS 103 ? NZ  ? A LYS 103 NZ  
6  1 Y 1 A LYS 107 ? CG  ? A LYS 107 CG  
7  1 Y 1 A LYS 107 ? CD  ? A LYS 107 CD  
8  1 Y 1 A LYS 107 ? CE  ? A LYS 107 CE  
9  1 Y 1 A LYS 107 ? NZ  ? A LYS 107 NZ  
10 1 Y 1 A LYS 152 ? CE  ? A LYS 152 CE  
11 1 Y 1 A LYS 152 ? NZ  ? A LYS 152 NZ  
12 1 Y 1 A LYS 187 ? CE  ? A LYS 187 CE  
13 1 Y 1 A LYS 187 ? NZ  ? A LYS 187 NZ  
14 1 Y 1 A GLU 223 ? CD  ? A GLU 223 CD  
15 1 Y 1 A GLU 223 ? OE1 ? A GLU 223 OE1 
16 1 Y 1 A GLU 223 ? OE2 ? A GLU 223 OE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? '5.8.0430 (refmacat 0.4.88)' 1 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? '5.8.0430 (refmacat 0.4.88)' 2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .                            3 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .                            4 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .                            5 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP  ? ? ? .                            6 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9HTA 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     90.06 
_cell.length_a_esd                 ? 
_cell.length_b                     90.06 
_cell.length_b_esd                 ? 
_cell.length_c                     98.12 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9HTA 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                154 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 32 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9HTA 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.02 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          59.34 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'MPD screen E7: 0.1 M Citric acid pH 4.0, 20% MPD' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2018-03-10 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.976 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.976 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9HTA 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.17 
_reflns.d_resolution_low                               40.93 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     23157 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           93.1 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                11.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          13.3 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               1.03 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.099 
_reflns.pdbx_Rpim_I_all                                0.040 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.090 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
8.95 40.93 ? 38.5 ? ? ? ? 400  ? ? ? ? ? ? ? ? ? ? ? 10.3 0.66 ? ? 0.045 0.018 ? 1 ? 0.999 ? ? 98.6 ? 0.041 ? ? ? ? ? ? ? ? ? 
2.17 2.24  ? 0.5  ? ? ? ? 1624 ? ? ? ? ? ? ? ? ? ? ? 11.2 1.03 ? ? 5.210 2.151 ? 2 ? 0.532 ? ? 76.4 ? 4.735 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            0.595 
_refine.aniso_B[1][2]                            0.298 
_refine.aniso_B[1][3]                            -0.000 
_refine.aniso_B[2][2]                            0.595 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            -1.930 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               59.004 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.950 
_refine.correlation_coeff_Fo_to_Fc_free          0.936 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9HTA 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.170 
_refine.ls_d_res_low                             40.926 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     23065 
_refine.ls_number_reflns_R_free                  1089 
_refine.ls_number_reflns_R_work                  21976 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    92.895 
_refine.ls_percent_reflns_R_free                 4.721 
_refine.ls_R_factor_all                          0.214 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2528 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2121 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.235 
_refine.pdbx_overall_ESU_R_Free                  0.200 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             7.311 
_refine.overall_SU_ML                            0.172 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.170 
_refine_hist.d_res_low                        40.926 
_refine_hist.number_atoms_solvent             43 
_refine_hist.number_atoms_total               2688 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2631 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         14 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.005  0.012  2708  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.002  0.016  2384  ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.482  1.805  3684  ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.564  1.751  5510  ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 6.994  5.000  322   ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 7.533  5.000  6     ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 13.600 10.000 447   ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 14.536 10.000 146   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.069  0.200  401   ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.006  0.020  3183  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.002  0.020  629   ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.207  0.200  536   ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.176  0.200  2281  ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.182  0.200  1345  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.074  0.200  1434  ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.128  0.200  90    ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.051  0.200  7     ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.146  0.200  30    ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.103  0.200  4     ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 4.642  5.792  1291  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.641  5.791  1292  ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 6.432  10.403 1612  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 6.430  10.401 1613  ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 4.568  6.137  1417  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.564  6.140  1415  ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 6.978  11.123 2072  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 6.976  11.123 2073  ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 9.215  69.609 11952 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 9.215  69.615 11946 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.170 2.226  1823 . 78 1510 87.1092  . 0.387 . . 0.387 . . . . . 0.393 . 20 . 0.912 0.886 0.372 
'X-RAY DIFFRACTION' 2.226 2.287  1754 . 17 310  18.6431  . 0.744 . . 0.737 . . . . . 0.823 . 20 . 0.697 0.643 0.842 
'X-RAY DIFFRACTION' 2.287 2.353  1703 . 91 1597 99.1192  . 0.350 . . 0.350 . . . . . 0.335 . 20 . 0.914 0.878 0.360 
'X-RAY DIFFRACTION' 2.353 2.425  1682 . 79 1601 99.8811  . 0.303 . . 0.301 . . . . . 0.280 . 20 . 0.940 0.926 0.337 
'X-RAY DIFFRACTION' 2.425 2.505  1616 . 62 1554 100.0000 . 0.270 . . 0.270 . . . . . 0.248 . 20 . 0.952 0.962 0.263 
'X-RAY DIFFRACTION' 2.505 2.592  1546 . 66 1480 100.0000 . 0.250 . . 0.245 . . . . . 0.220 . 20 . 0.962 0.915 0.393 
'X-RAY DIFFRACTION' 2.592 2.690  1507 . 66 1441 100.0000 . 0.223 . . 0.221 . . . . . 0.195 . 20 . 0.968 0.947 0.270 
'X-RAY DIFFRACTION' 2.690 2.799  1466 . 71 1395 100.0000 . 0.240 . . 0.239 . . . . . 0.212 . 20 . 0.963 0.954 0.256 
'X-RAY DIFFRACTION' 2.799 2.923  1404 . 61 1343 100.0000 . 0.234 . . 0.231 . . . . . 0.208 . 20 . 0.966 0.950 0.299 
'X-RAY DIFFRACTION' 2.923 3.065  1337 . 43 1294 100.0000 . 0.215 . . 0.213 . . . . . 0.196 . 20 . 0.970 0.953 0.297 
'X-RAY DIFFRACTION' 3.065 3.230  1271 . 55 1216 100.0000 . 0.226 . . 0.226 . . . . . 0.213 . 20 . 0.966 0.961 0.232 
'X-RAY DIFFRACTION' 3.230 3.424  1219 . 64 1151 99.6719  . 0.220 . . 0.217 . . . . . 0.205 . 20 . 0.968 0.955 0.276 
'X-RAY DIFFRACTION' 3.424 3.659  1137 . 57 1045 96.9217  . 0.242 . . 0.238 . . . . . 0.223 . 20 . 0.962 0.939 0.330 
'X-RAY DIFFRACTION' 3.659 3.949  1072 . 50 988  96.8284  . 0.289 . . 0.289 . . . . . 0.257 . 20 . 0.935 0.935 0.288 
'X-RAY DIFFRACTION' 3.949 4.322  994  . 33 957  99.5976  . 0.165 . . 0.164 . . . . . 0.172 . 20 . 0.984 0.984 0.183 
'X-RAY DIFFRACTION' 4.322 4.826  902  . 49 853  100.0000 . 0.139 . . 0.138 . . . . . 0.150 . 20 . 0.989 0.982 0.165 
'X-RAY DIFFRACTION' 4.826 5.559  809  . 35 774  100.0000 . 0.152 . . 0.150 . . . . . 0.162 . 20 . 0.988 0.981 0.193 
'X-RAY DIFFRACTION' 5.559 6.777  686  . 43 643  100.0000 . 0.186 . . 0.184 . . . . . 0.194 . 20 . 0.980 0.970 0.223 
'X-RAY DIFFRACTION' 6.777 9.456  545  . 41 504  100.0000 . 0.147 . . 0.143 . . . . . 0.160 . 20 . 0.986 0.974 0.196 
'X-RAY DIFFRACTION' 9.456 40.926 350  . 28 320  99.4286  . 0.226 . . 0.222 . . . . . 0.240 . 20 . 0.960 0.953 0.265 
# 
_struct.entry_id                     9HTA 
_struct.title                        'Dispersin from Terribacillus saccharophilus Dispts2 in complex with NAG-thiazoline' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9HTA 
_struct_keywords.text            'biofilm degradation, GH20, poly-N-acetylglucosamine, enzyme catalysis, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9HTA 
_struct_ref.pdbx_db_accession          9HTA 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9HTA 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 324 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             9HTA 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  324 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       324 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 430   ? 
1 MORE         2     ? 
1 'SSA (A^2)'  13190 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 17  ? ASN A 31  ? THR A 17  ASN A 31  1 ? 15 
HELX_P HELX_P2  AA2 THR A 66  ? LYS A 80  ? THR A 66  LYS A 80  1 ? 15 
HELX_P HELX_P3  AA3 SER A 94  ? ASP A 105 ? SER A 94  ASP A 105 1 ? 12 
HELX_P HELX_P4  AA4 ASP A 105 ? VAL A 113 ? ASP A 105 VAL A 113 1 ? 9  
HELX_P HELX_P5  AA5 ASN A 126 ? PHE A 144 ? ASN A 126 PHE A 144 1 ? 19 
HELX_P HELX_P6  AA6 GLN A 146 ? GLU A 150 ? GLN A 146 GLU A 150 5 ? 5  
HELX_P HELX_P7  AA7 HIS A 168 ? SER A 186 ? HIS A 168 SER A 186 1 ? 19 
HELX_P HELX_P8  AA8 THR A 198 ? ALA A 203 ? THR A 198 ALA A 203 1 ? 6  
HELX_P HELX_P9  AA9 ASN A 227 ? TRP A 234 ? ASN A 227 TRP A 234 1 ? 8  
HELX_P HELX_P10 AB1 THR A 255 ? TYR A 270 ? THR A 255 TYR A 270 1 ? 16 
HELX_P HELX_P11 AB2 SER A 306 ? LEU A 324 ? SER A 306 LEU A 324 1 ? 19 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          LEU 
_struct_mon_prot_cis.label_seq_id           90 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           LEU 
_struct_mon_prot_cis.auth_seq_id            90 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    91 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     91 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -5.79 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 10 ? 
AA2 ? 2  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2  ? parallel      
AA1 2 3  ? parallel      
AA1 3 4  ? parallel      
AA1 4 5  ? parallel      
AA1 5 6  ? parallel      
AA1 6 7  ? parallel      
AA1 7 8  ? parallel      
AA1 8 9  ? parallel      
AA1 9 10 ? parallel      
AA2 1 2  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  TYR A 247 ? PHE A 248 ? TYR A 247 PHE A 248 
AA1 2  VAL A 290 ? PHE A 297 ? VAL A 290 PHE A 297 
AA1 3  VAL A 238 ? ASN A 240 ? VAL A 238 ASN A 240 
AA1 4  SER A 210 ? TYR A 213 ? SER A 210 TYR A 213 
AA1 5  GLU A 189 ? TRP A 193 ? GLU A 189 TRP A 193 
AA1 6  ARG A 154 ? GLY A 158 ? ARG A 154 GLY A 158 
AA1 7  LEU A 83  ? LEU A 90  ? LEU A 83  LEU A 90  
AA1 8  TYR A 35  ? SER A 41  ? TYR A 35  SER A 41  
AA1 9  GLU A 4   ? ASP A 10  ? GLU A 4   ASP A 10  
AA1 10 VAL A 290 ? PHE A 297 ? VAL A 290 PHE A 297 
AA2 1  LYS A 274 ? PHE A 275 ? LYS A 274 PHE A 275 
AA2 2  HIS A 283 ? ALA A 284 ? HIS A 283 ALA A 284 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2  N PHE A 248 ? N PHE A 248 O THR A 296 ? O THR A 296 
AA1 2 3  O LYS A 291 ? O LYS A 291 N VAL A 238 ? N VAL A 238 
AA1 3 4  O TYR A 239 ? O TYR A 239 N TYR A 213 ? N TYR A 213 
AA1 4 5  O LEU A 212 ? O LEU A 212 N MET A 192 ? N MET A 192 
AA1 5 6  O GLN A 191 ? O GLN A 191 N LEU A 157 ? N LEU A 157 
AA1 6 7  O LEU A 157 ? O LEU A 157 N LEU A 90  ? N LEU A 90  
AA1 7 8  O ILE A 85  ? O ILE A 85  N VAL A 36  ? N VAL A 36  
AA1 8 9  O GLN A 37  ? O GLN A 37  N ILE A 7   ? N ILE A 7   
AA1 9 10 N THR A 8   ? N THR A 8   O PHE A 297 ? O PHE A 297 
AA2 1 2  N PHE A 275 ? N PHE A 275 O HIS A 283 ? O HIS A 283 
# 
_pdbx_entry_details.entry_id                   9HTA 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 10  ? ? -66.50  91.83  
2 1 ASP A 105 ? ? -162.70 85.00  
3 1 HIS A 168 ? ? -96.85  49.34  
4 1 ASN A 242 ? ? -31.16  115.22 
# 
_pdbx_unobs_or_zero_occ_residues.id               1 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num    1 
_pdbx_unobs_or_zero_occ_residues.polymer_flag     Y 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag   1 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id     A 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id     GLN 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id      1 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code     ? 
_pdbx_unobs_or_zero_occ_residues.label_asym_id    A 
_pdbx_unobs_or_zero_occ_residues.label_comp_id    GLN 
_pdbx_unobs_or_zero_occ_residues.label_seq_id     1 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
GLN N    N N N 74  
GLN CA   C N S 75  
GLN C    C N N 76  
GLN O    O N N 77  
GLN CB   C N N 78  
GLN CG   C N N 79  
GLN CD   C N N 80  
GLN OE1  O N N 81  
GLN NE2  N N N 82  
GLN OXT  O N N 83  
GLN H    H N N 84  
GLN H2   H N N 85  
GLN HA   H N N 86  
GLN HB2  H N N 87  
GLN HB3  H N N 88  
GLN HG2  H N N 89  
GLN HG3  H N N 90  
GLN HE21 H N N 91  
GLN HE22 H N N 92  
GLN HXT  H N N 93  
GLU N    N N N 94  
GLU CA   C N S 95  
GLU C    C N N 96  
GLU O    O N N 97  
GLU CB   C N N 98  
GLU CG   C N N 99  
GLU CD   C N N 100 
GLU OE1  O N N 101 
GLU OE2  O N N 102 
GLU OXT  O N N 103 
GLU H    H N N 104 
GLU H2   H N N 105 
GLU HA   H N N 106 
GLU HB2  H N N 107 
GLU HB3  H N N 108 
GLU HG2  H N N 109 
GLU HG3  H N N 110 
GLU HE2  H N N 111 
GLU HXT  H N N 112 
GLY N    N N N 113 
GLY CA   C N N 114 
GLY C    C N N 115 
GLY O    O N N 116 
GLY OXT  O N N 117 
GLY H    H N N 118 
GLY H2   H N N 119 
GLY HA2  H N N 120 
GLY HA3  H N N 121 
GLY HXT  H N N 122 
HIS N    N N N 123 
HIS CA   C N S 124 
HIS C    C N N 125 
HIS O    O N N 126 
HIS CB   C N N 127 
HIS CG   C Y N 128 
HIS ND1  N Y N 129 
HIS CD2  C Y N 130 
HIS CE1  C Y N 131 
HIS NE2  N Y N 132 
HIS OXT  O N N 133 
HIS H    H N N 134 
HIS H2   H N N 135 
HIS HA   H N N 136 
HIS HB2  H N N 137 
HIS HB3  H N N 138 
HIS HD1  H N N 139 
HIS HD2  H N N 140 
HIS HE1  H N N 141 
HIS HE2  H N N 142 
HIS HXT  H N N 143 
HOH O    O N N 144 
HOH H1   H N N 145 
HOH H2   H N N 146 
ILE N    N N N 147 
ILE CA   C N S 148 
ILE C    C N N 149 
ILE O    O N N 150 
ILE CB   C N S 151 
ILE CG1  C N N 152 
ILE CG2  C N N 153 
ILE CD1  C N N 154 
ILE OXT  O N N 155 
ILE H    H N N 156 
ILE H2   H N N 157 
ILE HA   H N N 158 
ILE HB   H N N 159 
ILE HG12 H N N 160 
ILE HG13 H N N 161 
ILE HG21 H N N 162 
ILE HG22 H N N 163 
ILE HG23 H N N 164 
ILE HD11 H N N 165 
ILE HD12 H N N 166 
ILE HD13 H N N 167 
ILE HXT  H N N 168 
LEU N    N N N 169 
LEU CA   C N S 170 
LEU C    C N N 171 
LEU O    O N N 172 
LEU CB   C N N 173 
LEU CG   C N N 174 
LEU CD1  C N N 175 
LEU CD2  C N N 176 
LEU OXT  O N N 177 
LEU H    H N N 178 
LEU H2   H N N 179 
LEU HA   H N N 180 
LEU HB2  H N N 181 
LEU HB3  H N N 182 
LEU HG   H N N 183 
LEU HD11 H N N 184 
LEU HD12 H N N 185 
LEU HD13 H N N 186 
LEU HD21 H N N 187 
LEU HD22 H N N 188 
LEU HD23 H N N 189 
LEU HXT  H N N 190 
LYS N    N N N 191 
LYS CA   C N S 192 
LYS C    C N N 193 
LYS O    O N N 194 
LYS CB   C N N 195 
LYS CG   C N N 196 
LYS CD   C N N 197 
LYS CE   C N N 198 
LYS NZ   N N N 199 
LYS OXT  O N N 200 
LYS H    H N N 201 
LYS H2   H N N 202 
LYS HA   H N N 203 
LYS HB2  H N N 204 
LYS HB3  H N N 205 
LYS HG2  H N N 206 
LYS HG3  H N N 207 
LYS HD2  H N N 208 
LYS HD3  H N N 209 
LYS HE2  H N N 210 
LYS HE3  H N N 211 
LYS HZ1  H N N 212 
LYS HZ2  H N N 213 
LYS HZ3  H N N 214 
LYS HXT  H N N 215 
MET N    N N N 216 
MET CA   C N S 217 
MET C    C N N 218 
MET O    O N N 219 
MET CB   C N N 220 
MET CG   C N N 221 
MET SD   S N N 222 
MET CE   C N N 223 
MET OXT  O N N 224 
MET H    H N N 225 
MET H2   H N N 226 
MET HA   H N N 227 
MET HB2  H N N 228 
MET HB3  H N N 229 
MET HG2  H N N 230 
MET HG3  H N N 231 
MET HE1  H N N 232 
MET HE2  H N N 233 
MET HE3  H N N 234 
MET HXT  H N N 235 
NGT C1   C N R 236 
NGT C2   C N R 237 
NGT C3   C N R 238 
NGT C4   C N S 239 
NGT C5   C N R 240 
NGT C6   C N N 241 
NGT C7   C N N 242 
NGT C8   C N N 243 
NGT N2   N N N 244 
NGT S1   S N N 245 
NGT O3   O N N 246 
NGT O4   O N N 247 
NGT O5   O N N 248 
NGT O6   O N N 249 
NGT HC1  H N N 250 
NGT HC2  H N N 251 
NGT HC3  H N N 252 
NGT HC4  H N N 253 
NGT HC5  H N N 254 
NGT HC61 H N N 255 
NGT HC62 H N N 256 
NGT HC81 H N N 257 
NGT HC82 H N N 258 
NGT HC83 H N N 259 
NGT HO3  H N N 260 
NGT HO4  H N N 261 
NGT HO6  H N N 262 
PHE N    N N N 263 
PHE CA   C N S 264 
PHE C    C N N 265 
PHE O    O N N 266 
PHE CB   C N N 267 
PHE CG   C Y N 268 
PHE CD1  C Y N 269 
PHE CD2  C Y N 270 
PHE CE1  C Y N 271 
PHE CE2  C Y N 272 
PHE CZ   C Y N 273 
PHE OXT  O N N 274 
PHE H    H N N 275 
PHE H2   H N N 276 
PHE HA   H N N 277 
PHE HB2  H N N 278 
PHE HB3  H N N 279 
PHE HD1  H N N 280 
PHE HD2  H N N 281 
PHE HE1  H N N 282 
PHE HE2  H N N 283 
PHE HZ   H N N 284 
PHE HXT  H N N 285 
PRO N    N N N 286 
PRO CA   C N S 287 
PRO C    C N N 288 
PRO O    O N N 289 
PRO CB   C N N 290 
PRO CG   C N N 291 
PRO CD   C N N 292 
PRO OXT  O N N 293 
PRO H    H N N 294 
PRO HA   H N N 295 
PRO HB2  H N N 296 
PRO HB3  H N N 297 
PRO HG2  H N N 298 
PRO HG3  H N N 299 
PRO HD2  H N N 300 
PRO HD3  H N N 301 
PRO HXT  H N N 302 
SER N    N N N 303 
SER CA   C N S 304 
SER C    C N N 305 
SER O    O N N 306 
SER CB   C N N 307 
SER OG   O N N 308 
SER OXT  O N N 309 
SER H    H N N 310 
SER H2   H N N 311 
SER HA   H N N 312 
SER HB2  H N N 313 
SER HB3  H N N 314 
SER HG   H N N 315 
SER HXT  H N N 316 
THR N    N N N 317 
THR CA   C N S 318 
THR C    C N N 319 
THR O    O N N 320 
THR CB   C N R 321 
THR OG1  O N N 322 
THR CG2  C N N 323 
THR OXT  O N N 324 
THR H    H N N 325 
THR H2   H N N 326 
THR HA   H N N 327 
THR HB   H N N 328 
THR HG1  H N N 329 
THR HG21 H N N 330 
THR HG22 H N N 331 
THR HG23 H N N 332 
THR HXT  H N N 333 
TRP N    N N N 334 
TRP CA   C N S 335 
TRP C    C N N 336 
TRP O    O N N 337 
TRP CB   C N N 338 
TRP CG   C Y N 339 
TRP CD1  C Y N 340 
TRP CD2  C Y N 341 
TRP NE1  N Y N 342 
TRP CE2  C Y N 343 
TRP CE3  C Y N 344 
TRP CZ2  C Y N 345 
TRP CZ3  C Y N 346 
TRP CH2  C Y N 347 
TRP OXT  O N N 348 
TRP H    H N N 349 
TRP H2   H N N 350 
TRP HA   H N N 351 
TRP HB2  H N N 352 
TRP HB3  H N N 353 
TRP HD1  H N N 354 
TRP HE1  H N N 355 
TRP HE3  H N N 356 
TRP HZ2  H N N 357 
TRP HZ3  H N N 358 
TRP HH2  H N N 359 
TRP HXT  H N N 360 
TYR N    N N N 361 
TYR CA   C N S 362 
TYR C    C N N 363 
TYR O    O N N 364 
TYR CB   C N N 365 
TYR CG   C Y N 366 
TYR CD1  C Y N 367 
TYR CD2  C Y N 368 
TYR CE1  C Y N 369 
TYR CE2  C Y N 370 
TYR CZ   C Y N 371 
TYR OH   O N N 372 
TYR OXT  O N N 373 
TYR H    H N N 374 
TYR H2   H N N 375 
TYR HA   H N N 376 
TYR HB2  H N N 377 
TYR HB3  H N N 378 
TYR HD1  H N N 379 
TYR HD2  H N N 380 
TYR HE1  H N N 381 
TYR HE2  H N N 382 
TYR HH   H N N 383 
TYR HXT  H N N 384 
VAL N    N N N 385 
VAL CA   C N S 386 
VAL C    C N N 387 
VAL O    O N N 388 
VAL CB   C N N 389 
VAL CG1  C N N 390 
VAL CG2  C N N 391 
VAL OXT  O N N 392 
VAL H    H N N 393 
VAL H2   H N N 394 
VAL HA   H N N 395 
VAL HB   H N N 396 
VAL HG11 H N N 397 
VAL HG12 H N N 398 
VAL HG13 H N N 399 
VAL HG21 H N N 400 
VAL HG22 H N N 401 
VAL HG23 H N N 402 
VAL HXT  H N N 403 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
GLN N   CA   sing N N 70  
GLN N   H    sing N N 71  
GLN N   H2   sing N N 72  
GLN CA  C    sing N N 73  
GLN CA  CB   sing N N 74  
GLN CA  HA   sing N N 75  
GLN C   O    doub N N 76  
GLN C   OXT  sing N N 77  
GLN CB  CG   sing N N 78  
GLN CB  HB2  sing N N 79  
GLN CB  HB3  sing N N 80  
GLN CG  CD   sing N N 81  
GLN CG  HG2  sing N N 82  
GLN CG  HG3  sing N N 83  
GLN CD  OE1  doub N N 84  
GLN CD  NE2  sing N N 85  
GLN NE2 HE21 sing N N 86  
GLN NE2 HE22 sing N N 87  
GLN OXT HXT  sing N N 88  
GLU N   CA   sing N N 89  
GLU N   H    sing N N 90  
GLU N   H2   sing N N 91  
GLU CA  C    sing N N 92  
GLU CA  CB   sing N N 93  
GLU CA  HA   sing N N 94  
GLU C   O    doub N N 95  
GLU C   OXT  sing N N 96  
GLU CB  CG   sing N N 97  
GLU CB  HB2  sing N N 98  
GLU CB  HB3  sing N N 99  
GLU CG  CD   sing N N 100 
GLU CG  HG2  sing N N 101 
GLU CG  HG3  sing N N 102 
GLU CD  OE1  doub N N 103 
GLU CD  OE2  sing N N 104 
GLU OE2 HE2  sing N N 105 
GLU OXT HXT  sing N N 106 
GLY N   CA   sing N N 107 
GLY N   H    sing N N 108 
GLY N   H2   sing N N 109 
GLY CA  C    sing N N 110 
GLY CA  HA2  sing N N 111 
GLY CA  HA3  sing N N 112 
GLY C   O    doub N N 113 
GLY C   OXT  sing N N 114 
GLY OXT HXT  sing N N 115 
HIS N   CA   sing N N 116 
HIS N   H    sing N N 117 
HIS N   H2   sing N N 118 
HIS CA  C    sing N N 119 
HIS CA  CB   sing N N 120 
HIS CA  HA   sing N N 121 
HIS C   O    doub N N 122 
HIS C   OXT  sing N N 123 
HIS CB  CG   sing N N 124 
HIS CB  HB2  sing N N 125 
HIS CB  HB3  sing N N 126 
HIS CG  ND1  sing Y N 127 
HIS CG  CD2  doub Y N 128 
HIS ND1 CE1  doub Y N 129 
HIS ND1 HD1  sing N N 130 
HIS CD2 NE2  sing Y N 131 
HIS CD2 HD2  sing N N 132 
HIS CE1 NE2  sing Y N 133 
HIS CE1 HE1  sing N N 134 
HIS NE2 HE2  sing N N 135 
HIS OXT HXT  sing N N 136 
HOH O   H1   sing N N 137 
HOH O   H2   sing N N 138 
ILE N   CA   sing N N 139 
ILE N   H    sing N N 140 
ILE N   H2   sing N N 141 
ILE CA  C    sing N N 142 
ILE CA  CB   sing N N 143 
ILE CA  HA   sing N N 144 
ILE C   O    doub N N 145 
ILE C   OXT  sing N N 146 
ILE CB  CG1  sing N N 147 
ILE CB  CG2  sing N N 148 
ILE CB  HB   sing N N 149 
ILE CG1 CD1  sing N N 150 
ILE CG1 HG12 sing N N 151 
ILE CG1 HG13 sing N N 152 
ILE CG2 HG21 sing N N 153 
ILE CG2 HG22 sing N N 154 
ILE CG2 HG23 sing N N 155 
ILE CD1 HD11 sing N N 156 
ILE CD1 HD12 sing N N 157 
ILE CD1 HD13 sing N N 158 
ILE OXT HXT  sing N N 159 
LEU N   CA   sing N N 160 
LEU N   H    sing N N 161 
LEU N   H2   sing N N 162 
LEU CA  C    sing N N 163 
LEU CA  CB   sing N N 164 
LEU CA  HA   sing N N 165 
LEU C   O    doub N N 166 
LEU C   OXT  sing N N 167 
LEU CB  CG   sing N N 168 
LEU CB  HB2  sing N N 169 
LEU CB  HB3  sing N N 170 
LEU CG  CD1  sing N N 171 
LEU CG  CD2  sing N N 172 
LEU CG  HG   sing N N 173 
LEU CD1 HD11 sing N N 174 
LEU CD1 HD12 sing N N 175 
LEU CD1 HD13 sing N N 176 
LEU CD2 HD21 sing N N 177 
LEU CD2 HD22 sing N N 178 
LEU CD2 HD23 sing N N 179 
LEU OXT HXT  sing N N 180 
LYS N   CA   sing N N 181 
LYS N   H    sing N N 182 
LYS N   H2   sing N N 183 
LYS CA  C    sing N N 184 
LYS CA  CB   sing N N 185 
LYS CA  HA   sing N N 186 
LYS C   O    doub N N 187 
LYS C   OXT  sing N N 188 
LYS CB  CG   sing N N 189 
LYS CB  HB2  sing N N 190 
LYS CB  HB3  sing N N 191 
LYS CG  CD   sing N N 192 
LYS CG  HG2  sing N N 193 
LYS CG  HG3  sing N N 194 
LYS CD  CE   sing N N 195 
LYS CD  HD2  sing N N 196 
LYS CD  HD3  sing N N 197 
LYS CE  NZ   sing N N 198 
LYS CE  HE2  sing N N 199 
LYS CE  HE3  sing N N 200 
LYS NZ  HZ1  sing N N 201 
LYS NZ  HZ2  sing N N 202 
LYS NZ  HZ3  sing N N 203 
LYS OXT HXT  sing N N 204 
MET N   CA   sing N N 205 
MET N   H    sing N N 206 
MET N   H2   sing N N 207 
MET CA  C    sing N N 208 
MET CA  CB   sing N N 209 
MET CA  HA   sing N N 210 
MET C   O    doub N N 211 
MET C   OXT  sing N N 212 
MET CB  CG   sing N N 213 
MET CB  HB2  sing N N 214 
MET CB  HB3  sing N N 215 
MET CG  SD   sing N N 216 
MET CG  HG2  sing N N 217 
MET CG  HG3  sing N N 218 
MET SD  CE   sing N N 219 
MET CE  HE1  sing N N 220 
MET CE  HE2  sing N N 221 
MET CE  HE3  sing N N 222 
MET OXT HXT  sing N N 223 
NGT C1  C2   sing N N 224 
NGT C1  S1   sing N N 225 
NGT C1  O5   sing N N 226 
NGT C1  HC1  sing N N 227 
NGT C2  C3   sing N N 228 
NGT C2  N2   sing N N 229 
NGT C2  HC2  sing N N 230 
NGT C3  C4   sing N N 231 
NGT C3  O3   sing N N 232 
NGT C3  HC3  sing N N 233 
NGT C4  C5   sing N N 234 
NGT C4  O4   sing N N 235 
NGT C4  HC4  sing N N 236 
NGT C5  C6   sing N N 237 
NGT C5  O5   sing N N 238 
NGT C5  HC5  sing N N 239 
NGT C6  O6   sing N N 240 
NGT C6  HC61 sing N N 241 
NGT C6  HC62 sing N N 242 
NGT C7  C8   sing N N 243 
NGT C7  N2   doub N N 244 
NGT C7  S1   sing N N 245 
NGT C8  HC81 sing N N 246 
NGT C8  HC82 sing N N 247 
NGT C8  HC83 sing N N 248 
NGT O3  HO3  sing N N 249 
NGT O4  HO4  sing N N 250 
NGT O6  HO6  sing N N 251 
PHE N   CA   sing N N 252 
PHE N   H    sing N N 253 
PHE N   H2   sing N N 254 
PHE CA  C    sing N N 255 
PHE CA  CB   sing N N 256 
PHE CA  HA   sing N N 257 
PHE C   O    doub N N 258 
PHE C   OXT  sing N N 259 
PHE CB  CG   sing N N 260 
PHE CB  HB2  sing N N 261 
PHE CB  HB3  sing N N 262 
PHE CG  CD1  doub Y N 263 
PHE CG  CD2  sing Y N 264 
PHE CD1 CE1  sing Y N 265 
PHE CD1 HD1  sing N N 266 
PHE CD2 CE2  doub Y N 267 
PHE CD2 HD2  sing N N 268 
PHE CE1 CZ   doub Y N 269 
PHE CE1 HE1  sing N N 270 
PHE CE2 CZ   sing Y N 271 
PHE CE2 HE2  sing N N 272 
PHE CZ  HZ   sing N N 273 
PHE OXT HXT  sing N N 274 
PRO N   CA   sing N N 275 
PRO N   CD   sing N N 276 
PRO N   H    sing N N 277 
PRO CA  C    sing N N 278 
PRO CA  CB   sing N N 279 
PRO CA  HA   sing N N 280 
PRO C   O    doub N N 281 
PRO C   OXT  sing N N 282 
PRO CB  CG   sing N N 283 
PRO CB  HB2  sing N N 284 
PRO CB  HB3  sing N N 285 
PRO CG  CD   sing N N 286 
PRO CG  HG2  sing N N 287 
PRO CG  HG3  sing N N 288 
PRO CD  HD2  sing N N 289 
PRO CD  HD3  sing N N 290 
PRO OXT HXT  sing N N 291 
SER N   CA   sing N N 292 
SER N   H    sing N N 293 
SER N   H2   sing N N 294 
SER CA  C    sing N N 295 
SER CA  CB   sing N N 296 
SER CA  HA   sing N N 297 
SER C   O    doub N N 298 
SER C   OXT  sing N N 299 
SER CB  OG   sing N N 300 
SER CB  HB2  sing N N 301 
SER CB  HB3  sing N N 302 
SER OG  HG   sing N N 303 
SER OXT HXT  sing N N 304 
THR N   CA   sing N N 305 
THR N   H    sing N N 306 
THR N   H2   sing N N 307 
THR CA  C    sing N N 308 
THR CA  CB   sing N N 309 
THR CA  HA   sing N N 310 
THR C   O    doub N N 311 
THR C   OXT  sing N N 312 
THR CB  OG1  sing N N 313 
THR CB  CG2  sing N N 314 
THR CB  HB   sing N N 315 
THR OG1 HG1  sing N N 316 
THR CG2 HG21 sing N N 317 
THR CG2 HG22 sing N N 318 
THR CG2 HG23 sing N N 319 
THR OXT HXT  sing N N 320 
TRP N   CA   sing N N 321 
TRP N   H    sing N N 322 
TRP N   H2   sing N N 323 
TRP CA  C    sing N N 324 
TRP CA  CB   sing N N 325 
TRP CA  HA   sing N N 326 
TRP C   O    doub N N 327 
TRP C   OXT  sing N N 328 
TRP CB  CG   sing N N 329 
TRP CB  HB2  sing N N 330 
TRP CB  HB3  sing N N 331 
TRP CG  CD1  doub Y N 332 
TRP CG  CD2  sing Y N 333 
TRP CD1 NE1  sing Y N 334 
TRP CD1 HD1  sing N N 335 
TRP CD2 CE2  doub Y N 336 
TRP CD2 CE3  sing Y N 337 
TRP NE1 CE2  sing Y N 338 
TRP NE1 HE1  sing N N 339 
TRP CE2 CZ2  sing Y N 340 
TRP CE3 CZ3  doub Y N 341 
TRP CE3 HE3  sing N N 342 
TRP CZ2 CH2  doub Y N 343 
TRP CZ2 HZ2  sing N N 344 
TRP CZ3 CH2  sing Y N 345 
TRP CZ3 HZ3  sing N N 346 
TRP CH2 HH2  sing N N 347 
TRP OXT HXT  sing N N 348 
TYR N   CA   sing N N 349 
TYR N   H    sing N N 350 
TYR N   H2   sing N N 351 
TYR CA  C    sing N N 352 
TYR CA  CB   sing N N 353 
TYR CA  HA   sing N N 354 
TYR C   O    doub N N 355 
TYR C   OXT  sing N N 356 
TYR CB  CG   sing N N 357 
TYR CB  HB2  sing N N 358 
TYR CB  HB3  sing N N 359 
TYR CG  CD1  doub Y N 360 
TYR CG  CD2  sing Y N 361 
TYR CD1 CE1  sing Y N 362 
TYR CD1 HD1  sing N N 363 
TYR CD2 CE2  doub Y N 364 
TYR CD2 HD2  sing N N 365 
TYR CE1 CZ   doub Y N 366 
TYR CE1 HE1  sing N N 367 
TYR CE2 CZ   sing Y N 368 
TYR CE2 HE2  sing N N 369 
TYR CZ  OH   sing N N 370 
TYR OH  HH   sing N N 371 
TYR OXT HXT  sing N N 372 
VAL N   CA   sing N N 373 
VAL N   H    sing N N 374 
VAL N   H2   sing N N 375 
VAL CA  C    sing N N 376 
VAL CA  CB   sing N N 377 
VAL CA  HA   sing N N 378 
VAL C   O    doub N N 379 
VAL C   OXT  sing N N 380 
VAL CB  CG1  sing N N 381 
VAL CB  CG2  sing N N 382 
VAL CB  HB   sing N N 383 
VAL CG1 HG11 sing N N 384 
VAL CG1 HG12 sing N N 385 
VAL CG1 HG13 sing N N 386 
VAL CG2 HG21 sing N N 387 
VAL CG2 HG22 sing N N 388 
VAL CG2 HG23 sing N N 389 
VAL OXT HXT  sing N N 390 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8qb6 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9HTA 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.011104 
_atom_sites.fract_transf_matrix[1][2]   0.006411 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.012821 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.010192 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
H 1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997 0.0030   
N 7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O 8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S 16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0486   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N N    . ASP A 1 2   ? -48.976 -21.616 -18.659 1 89.757  ? 2   ASP A N    1 ? 
ATOM   2    C CA   . ASP A 1 2   ? -49.01  -20.277 -18.012 1 92.794  ? 2   ASP A CA   1 ? 
ATOM   3    C C    . ASP A 1 2   ? -47.584 -19.81  -17.734 1 86.306  ? 2   ASP A C    1 ? 
ATOM   4    O O    . ASP A 1 2   ? -46.836 -20.511 -17.058 1 91.421  ? 2   ASP A O    1 ? 
ATOM   5    C CB   . ASP A 1 2   ? -49.842 -20.308 -16.739 1 98.878  ? 2   ASP A CB   1 ? 
ATOM   6    C CG   . ASP A 1 2   ? -51.35  -20.343 -16.941 1 109.127 ? 2   ASP A CG   1 ? 
ATOM   7    O OD1  . ASP A 1 2   ? -51.808 -20.015 -18.059 1 102.879 ? 2   ASP A OD1  1 ? 
ATOM   8    O OD2  . ASP A 1 2   ? -52.053 -20.71  -15.979 1 113.329 ? 2   ASP A OD2  1 ? 
ATOM   9    H H    . ASP A 1 2   ? -49.812 -21.881 -18.868 1 90.759  ? 2   ASP A H    1 c 
ATOM   10   H HA   . ASP A 1 2   ? -49.431 -19.648 -18.639 1 91.812  ? 2   ASP A HA   1 c 
ATOM   11   H HB2  . ASP A 1 2   ? -49.588 -21.099 -16.219 1 99.615  ? 2   ASP A HB2  1 c 
ATOM   12   H HB3  . ASP A 1 2   ? -49.631 -19.516 -16.201 1 99.608  ? 2   ASP A HB3  1 c 
ATOM   13   N N    . GLN A 1 3   ? -47.241 -18.626 -18.265 1 70.283  ? 3   GLN A N    1 ? 
ATOM   14   C CA   . GLN A 1 3   ? -45.995 -17.94  -17.97  1 65.809  ? 3   GLN A CA   1 ? 
ATOM   15   C C    . GLN A 1 3   ? -46.253 -16.799 -16.985 1 66.889  ? 3   GLN A C    1 ? 
ATOM   16   O O    . GLN A 1 3   ? -47.189 -16.017 -17.14  1 68.463  ? 3   GLN A O    1 ? 
ATOM   17   C CB   . GLN A 1 3   ? -45.363 -17.357 -19.235 1 63.61   ? 3   GLN A CB   1 ? 
ATOM   18   C CG   . GLN A 1 3   ? -44.967 -18.369 -20.311 1 67.907  ? 3   GLN A CG   1 ? 
ATOM   19   C CD   . GLN A 1 3   ? -43.887 -19.35  -19.887 1 65.342  ? 3   GLN A CD   1 ? 
ATOM   20   O OE1  . GLN A 1 3   ? -42.698 -19.17  -20.16  1 62.684  ? 3   GLN A OE1  1 ? 
ATOM   21   N NE2  . GLN A 1 3   ? -44.295 -20.408 -19.207 1 62.549  ? 3   GLN A NE2  1 ? 
ATOM   22   H H    . GLN A 1 3   ? -47.819 -18.225 -18.849 1 72.992  ? 3   GLN A H    1 c 
ATOM   23   H HA   . GLN A 1 3   ? -45.363 -18.582 -17.56  1 66.532  ? 3   GLN A HA   1 c 
ATOM   24   H HB2  . GLN A 1 3   ? -45.996 -16.719 -19.626 1 65.068  ? 3   GLN A HB2  1 c 
ATOM   25   H HB3  . GLN A 1 3   ? -44.564 -16.852 -18.974 1 65.076  ? 3   GLN A HB3  1 c 
ATOM   26   H HG2  . GLN A 1 3   ? -45.761 -18.88  -20.576 1 66.301  ? 3   GLN A HG2  1 c 
ATOM   27   H HG3  . GLN A 1 3   ? -44.65  -17.885 -21.103 1 66.317  ? 3   GLN A HG3  1 c 
ATOM   28   H HE21 . GLN A 1 3   ? -43.867 -20.651 -18.469 1 63.401  ? 3   GLN A HE21 1 c 
ATOM   29   H HE22 . GLN A 1 3   ? -44.995 -20.873 -19.49  1 63.418  ? 3   GLN A HE22 1 c 
ATOM   30   N N    . GLU A 1 4   ? -45.389 -16.667 -15.981 1 57.821  ? 4   GLU A N    1 ? 
ATOM   31   C CA   . GLU A 1 4   ? -45.485 -15.523 -15.095 1 55.584  ? 4   GLU A CA   1 ? 
ATOM   32   C C    . GLU A 1 4   ? -44.833 -14.301 -15.745 1 53.445  ? 4   GLU A C    1 ? 
ATOM   33   O O    . GLU A 1 4   ? -43.904 -14.439 -16.536 1 50.114  ? 4   GLU A O    1 ? 
ATOM   34   C CB   . GLU A 1 4   ? -44.846 -15.851 -13.755 1 61.02   ? 4   GLU A CB   1 ? 
ATOM   35   C CG   . GLU A 1 4   ? -45.704 -16.749 -12.872 1 62.408  ? 4   GLU A CG   1 ? 
ATOM   36   C CD   . GLU A 1 4   ? -44.913 -17.097 -11.631 1 71.072  ? 4   GLU A CD   1 ? 
ATOM   37   O OE1  . GLU A 1 4   ? -44.601 -18.298 -11.448 1 82.828  ? 4   GLU A OE1  1 ? 
ATOM   38   O OE2  . GLU A 1 4   ? -44.561 -16.149 -10.886 1 69.414  ? 4   GLU A OE2  1 ? 
ATOM   39   H H    . GLU A 1 4   ? -44.732 -17.288 -15.846 1 59.455  ? 4   GLU A H    1 c 
ATOM   40   H HA   . GLU A 1 4   ? -46.44  -15.333 -14.935 1 56.621  ? 4   GLU A HA   1 c 
ATOM   41   H HB2  . GLU A 1 4   ? -43.981 -16.284 -13.913 1 60.09   ? 4   GLU A HB2  1 c 
ATOM   42   H HB3  . GLU A 1 4   ? -44.675 -15.013 -13.276 1 60.055  ? 4   GLU A HB3  1 c 
ATOM   43   H HG2  . GLU A 1 4   ? -46.526 -16.28  -12.614 1 63.991  ? 4   GLU A HG2  1 c 
ATOM   44   H HG3  . GLU A 1 4   ? -45.937 -17.57  -13.354 1 64.074  ? 4   GLU A HG3  1 c 
ATOM   45   N N    . LYS A 1 5   ? -45.336 -13.105 -15.4   1 47.794  ? 5   LYS A N    1 ? 
ATOM   46   C CA   . LYS A 1 5   ? -44.687 -11.856 -15.767 1 49.678  ? 5   LYS A CA   1 ? 
ATOM   47   C C    . LYS A 1 5   ? -44.515 -11.04  -14.493 1 46.037  ? 5   LYS A C    1 ? 
ATOM   48   O O    . LYS A 1 5   ? -45.38  -11.007 -13.62  1 42.893  ? 5   LYS A O    1 ? 
ATOM   49   C CB   . LYS A 1 5   ? -45.45  -11.148 -16.889 1 55.286  ? 5   LYS A CB   1 ? 
ATOM   50   C CG   . LYS A 1 5   ? -45.707 -11.987 -18.159 1 56.756  ? 5   LYS A CG   1 ? 
ATOM   51   C CD   . LYS A 1 5   ? -46.533 -11.339 -19.271 1 59.566  ? 5   LYS A CD   1 ? 
ATOM   52   C CE   . LYS A 1 5   ? -45.715 -10.527 -20.258 1 64.85   ? 5   LYS A CE   1 ? 
ATOM   53   N NZ   . LYS A 1 5   ? -46.421 -10.157 -21.498 1 63.54   ? 5   LYS A NZ   1 ? 
ATOM   54   H H    . LYS A 1 5   ? -46.113 -13.068 -14.921 1 49.6    ? 5   LYS A H    1 c 
ATOM   55   H HA   . LYS A 1 5   ? -43.787 -12.065 -16.118 1 49.47   ? 5   LYS A HA   1 c 
ATOM   56   H HB2  . LYS A 1 5   ? -46.317 -10.855 -16.536 1 54.27   ? 5   LYS A HB2  1 c 
ATOM   57   H HB3  . LYS A 1 5   ? -44.952 -10.344 -17.147 1 54.256  ? 5   LYS A HB3  1 c 
ATOM   58   H HG2  . LYS A 1 5   ? -44.836 -12.246 -18.529 1 57.111  ? 5   LYS A HG2  1 c 
ATOM   59   H HG3  . LYS A 1 5   ? -46.158 -12.815 -17.888 1 56.992  ? 5   LYS A HG3  1 c 
ATOM   60   H HD2  . LYS A 1 5   ? -47.01  -12.044 -19.76  1 60.074  ? 5   LYS A HD2  1 c 
ATOM   61   H HD3  . LYS A 1 5   ? -47.207 -10.753 -18.862 1 60.074  ? 5   LYS A HD3  1 c 
ATOM   62   H HE2  . LYS A 1 5   ? -45.417 -9.71   -19.818 1 63.267  ? 5   LYS A HE2  1 c 
ATOM   63   H HE3  . LYS A 1 5   ? -44.92  -11.034 -20.501 1 63.118  ? 5   LYS A HE3  1 c 
ATOM   64   H HZ1  . LYS A 1 5   ? -47.149 -9.656  -21.298 1 63.94   ? 5   LYS A HZ1  1 c 
ATOM   65   H HZ2  . LYS A 1 5   ? -46.685 -10.905 -21.935 1 63.94   ? 5   LYS A HZ2  1 c 
ATOM   66   H HZ3  . LYS A 1 5   ? -45.869 -9.678  -22.034 1 63.94   ? 5   LYS A HZ3  1 c 
ATOM   67   N N    . GLY A 1 6   ? -43.345 -10.439 -14.339 1 43.039  ? 6   GLY A N    1 ? 
ATOM   68   C CA   . GLY A 1 6   ? -43.058 -9.751  -13.101 1 39.833  ? 6   GLY A CA   1 ? 
ATOM   69   C C    . GLY A 1 6   ? -42.294 -8.477  -13.362 1 36.589  ? 6   GLY A C    1 ? 
ATOM   70   O O    . GLY A 1 6   ? -41.72  -8.297  -14.423 1 41.793  ? 6   GLY A O    1 ? 
ATOM   71   H H    . GLY A 1 6   ? -42.72  -10.448 -15.006 1 43.028  ? 6   GLY A H    1 c 
ATOM   72   H HA2  . GLY A 1 6   ? -43.898 -9.536  -12.639 1 39.863  ? 6   GLY A HA2  1 c 
ATOM   73   H HA3  . GLY A 1 6   ? -42.53  -10.341 -12.516 1 39.825  ? 6   GLY A HA3  1 c 
ATOM   74   N N    . ILE A 1 7   ? -42.276 -7.611  -12.359 1 37.167  ? 7   ILE A N    1 ? 
ATOM   75   C CA   . ILE A 1 7   ? -41.458 -6.416  -12.431 1 39.3    ? 7   ILE A CA   1 ? 
ATOM   76   C C    . ILE A 1 7   ? -40.433 -6.516  -11.311 1 40.702  ? 7   ILE A C    1 ? 
ATOM   77   O O    . ILE A 1 7   ? -40.771 -6.92   -10.212 1 39.947  ? 7   ILE A O    1 ? 
ATOM   78   C CB   . ILE A 1 7   ? -42.327 -5.15   -12.314 1 41.74   ? 7   ILE A CB   1 ? 
ATOM   79   C CG1  . ILE A 1 7   ? -43.396 -5.11   -13.401 1 43.356  ? 7   ILE A CG1  1 ? 
ATOM   80   C CG2  . ILE A 1 7   ? -41.472 -3.883  -12.313 1 44.302  ? 7   ILE A CG2  1 ? 
ATOM   81   C CD1  . ILE A 1 7   ? -42.862 -4.972  -14.811 1 44.15   ? 7   ILE A CD1  1 ? 
ATOM   82   H H    . ILE A 1 7   ? -42.781 -7.761  -11.611 1 37.531  ? 7   ILE A H    1 c 
ATOM   83   H HA   . ILE A 1 7   ? -40.991 -6.394  -13.283 1 39.616  ? 7   ILE A HA   1 c 
ATOM   84   H HB   . ILE A 1 7   ? -42.788 -5.193  -11.454 1 42.097  ? 7   ILE A HB   1 c 
ATOM   85   H HG12 . ILE A 1 7   ? -43.94  -5.922  -13.346 1 43.14   ? 7   ILE A HG12 1 c 
ATOM   86   H HG13 . ILE A 1 7   ? -43.982 -4.348  -13.224 1 43.225  ? 7   ILE A HG13 1 c 
ATOM   87   H HG21 . ILE A 1 7   ? -41.999 -3.132  -12.633 1 43.523  ? 7   ILE A HG21 1 c 
ATOM   88   H HG22 . ILE A 1 7   ? -40.703 -4.007  -12.894 1 43.505  ? 7   ILE A HG22 1 c 
ATOM   89   H HG23 . ILE A 1 7   ? -41.165 -3.698  -11.409 1 43.514  ? 7   ILE A HG23 1 c 
ATOM   90   H HD11 . ILE A 1 7   ? -42.297 -4.18   -14.884 1 43.902  ? 7   ILE A HD11 1 c 
ATOM   91   H HD12 . ILE A 1 7   ? -43.615 -4.886  -15.425 1 43.898  ? 7   ILE A HD12 1 c 
ATOM   92   H HD13 . ILE A 1 7   ? -42.342 -5.762  -15.051 1 43.848  ? 7   ILE A HD13 1 c 
ATOM   93   N N    . THR A 1 8   ? -39.186 -6.168  -11.611 1 39.367  ? 8   THR A N    1 ? 
ATOM   94   C CA   . THR A 1 8   ? -38.144 -6.169  -10.608 1 44.704  ? 8   THR A CA   1 ? 
ATOM   95   C C    . THR A 1 8   ? -37.714 -4.716  -10.421 1 43.327  ? 8   THR A C    1 ? 
ATOM   96   O O    . THR A 1 8   ? -37.493 -4.032  -11.42  1 45.414  ? 8   THR A O    1 ? 
ATOM   97   C CB   . THR A 1 8   ? -37.036 -7.107  -11.109 1 45.094  ? 8   THR A CB   1 ? 
ATOM   98   O OG1  . THR A 1 8   ? -37.573 -8.425  -11.181 1 45.592  ? 8   THR A OG1  1 ? 
ATOM   99   C CG2  . THR A 1 8   ? -35.843 -7.188  -10.184 1 43.927  ? 8   THR A CG2  1 ? 
ATOM   100  H H    . THR A 1 8   ? -38.974 -5.92   -12.465 1 40.82   ? 8   THR A H    1 c 
ATOM   101  H HA   . THR A 1 8   ? -38.498 -6.518  -9.766  1 43.46   ? 8   THR A HA   1 c 
ATOM   102  H HB   . THR A 1 8   ? -36.745 -6.817  -12.005 1 44.888  ? 8   THR A HB   1 c 
ATOM   103  H HG21 . THR A 1 8   ? -35.286 -7.944  -10.438 1 44.263  ? 8   THR A HG21 1 c 
ATOM   104  H HG22 . THR A 1 8   ? -36.148 -7.305  -9.269  1 44.264  ? 8   THR A HG22 1 c 
ATOM   105  H HG23 . THR A 1 8   ? -35.323 -6.369  -10.249 1 44.245  ? 8   THR A HG23 1 c 
ATOM   106  N N    . ILE A 1 9   ? -37.641 -4.253  -9.157  1 48.704  ? 9   ILE A N    1 ? 
ATOM   107  C CA   . ILE A 1 9   ? -37.328 -2.858  -8.847  1 46.586  ? 9   ILE A CA   1 ? 
ATOM   108  C C    . ILE A 1 9   ? -36.112 -2.765  -7.917  1 43.119  ? 9   ILE A C    1 ? 
ATOM   109  O O    . ILE A 1 9   ? -36.153 -3.12   -6.746  1 51.953  ? 9   ILE A O    1 ? 
ATOM   110  C CB   . ILE A 1 9   ? -38.53  -2.107  -8.241  1 51.505  ? 9   ILE A CB   1 ? 
ATOM   111  C CG1  . ILE A 1 9   ? -39.868 -2.395  -8.931  1 50.482  ? 9   ILE A CG1  1 ? 
ATOM   112  C CG2  . ILE A 1 9   ? -38.249 -0.605  -8.259  1 54.485  ? 9   ILE A CG2  1 ? 
ATOM   113  C CD1  . ILE A 1 9   ? -41.075 -2.12   -8.047  1 50.578  ? 9   ILE A CD1  1 ? 
ATOM   114  H H    . ILE A 1 9   ? -37.786 -4.83   -8.462  1 46.847  ? 9   ILE A H    1 c 
ATOM   115  H HA   . ILE A 1 9   ? -37.101 -2.41   -9.683  1 47.198  ? 9   ILE A HA   1 c 
ATOM   116  H HB   . ILE A 1 9   ? -38.615 -2.384  -7.307  1 50.859  ? 9   ILE A HB   1 c 
ATOM   117  H HG12 . ILE A 1 9   ? -39.934 -1.844  -9.737  1 50.744  ? 9   ILE A HG12 1 c 
ATOM   118  H HG13 . ILE A 1 9   ? -39.894 -3.333  -9.206  1 50.688  ? 9   ILE A HG13 1 c 
ATOM   119  H HG21 . ILE A 1 9   ? -39.049 -0.119  -7.999  1 53.507  ? 9   ILE A HG21 1 c 
ATOM   120  H HG22 . ILE A 1 9   ? -37.986 -0.332  -9.154  1 53.511  ? 9   ILE A HG22 1 c 
ATOM   121  H HG23 . ILE A 1 9   ? -37.533 -0.396  -7.637  1 53.484  ? 9   ILE A HG23 1 c 
ATOM   122  H HD11 . ILE A 1 9   ? -40.963 -2.569  -7.188  1 50.557  ? 9   ILE A HD11 1 c 
ATOM   123  H HD12 . ILE A 1 9   ? -41.88  -2.456  -8.485  1 50.555  ? 9   ILE A HD12 1 c 
ATOM   124  H HD13 . ILE A 1 9   ? -41.163 -1.159  -7.901  1 50.57   ? 9   ILE A HD13 1 c 
ATOM   125  N N    . ASP A 1 10  ? -35.016 -2.262  -8.469  1 45.076  ? 10  ASP A N    1 ? 
ATOM   126  C CA   . ASP A 1 10  ? -33.84  -1.889  -7.711  1 44.375  ? 10  ASP A CA   1 ? 
ATOM   127  C C    . ASP A 1 10  ? -34.16  -0.696  -6.8    1 51.392  ? 10  ASP A C    1 ? 
ATOM   128  O O    . ASP A 1 10  ? -34.006 0.454   -7.213  1 50.078  ? 10  ASP A O    1 ? 
ATOM   129  C CB   . ASP A 1 10  ? -32.716 -1.581  -8.686  1 43.262  ? 10  ASP A CB   1 ? 
ATOM   130  C CG   . ASP A 1 10  ? -31.372 -1.228  -8.066  1 41.656  ? 10  ASP A CG   1 ? 
ATOM   131  O OD1  . ASP A 1 10  ? -31.276 -1.255  -6.828  1 43.823  ? 10  ASP A OD1  1 ? 
ATOM   132  O OD2  . ASP A 1 10  ? -30.438 -0.933  -8.845  1 42.772  ? 10  ASP A OD2  1 ? 
ATOM   133  H H    . ASP A 1 10  ? -34.993 -2.151  -9.376  1 44.475  ? 10  ASP A H    1 c 
ATOM   134  H HA   . ASP A 1 10  ? -33.568 -2.649  -7.156  1 45.549  ? 10  ASP A HA   1 c 
ATOM   135  H HB2  . ASP A 1 10  ? -32.586 -2.36   -9.267  1 43.162  ? 10  ASP A HB2  1 c 
ATOM   136  H HB3  . ASP A 1 10  ? -32.982 -0.828  -9.251  1 43.261  ? 10  ASP A HB3  1 c 
ATOM   137  N N    . ILE A 1 11  ? -34.574 -0.973  -5.555  1 51.753  ? 11  ILE A N    1 ? 
ATOM   138  C CA   . ILE A 1 11  ? -34.761 0.081   -4.57   1 48.897  ? 11  ILE A CA   1 ? 
ATOM   139  C C    . ILE A 1 11  ? -33.509 0.25    -3.712  1 55.266  ? 11  ILE A C    1 ? 
ATOM   140  O O    . ILE A 1 11  ? -33.601 0.877   -2.665  1 57.615  ? 11  ILE A O    1 ? 
ATOM   141  C CB   . ILE A 1 11  ? -36.026 -0.145  -3.719  1 49.498  ? 11  ILE A CB   1 ? 
ATOM   142  C CG1  . ILE A 1 11  ? -35.902 -1.253  -2.685  1 52.224  ? 11  ILE A CG1  1 ? 
ATOM   143  C CG2  . ILE A 1 11  ? -37.247 -0.38   -4.611  1 50.109  ? 11  ILE A CG2  1 ? 
ATOM   144  C CD1  . ILE A 1 11  ? -37.065 -1.282  -1.705  1 48.541  ? 11  ILE A CD1  1 ? 
ATOM   145  H H    . ILE A 1 11  ? -34.748 -1.838  -5.315  1 50.918  ? 11  ILE A H    1 c 
ATOM   146  H HA   . ILE A 1 11  ? -34.895 0.917   -5.052  1 50.784  ? 11  ILE A HA   1 c 
ATOM   147  H HB   . ILE A 1 11  ? -36.188 0.684   -3.227  1 50.037  ? 11  ILE A HB   1 c 
ATOM   148  H HG12 . ILE A 1 11  ? -35.855 -2.114  -3.148  1 50.75   ? 11  ILE A HG12 1 c 
ATOM   149  H HG13 . ILE A 1 11  ? -35.074 -1.137  -2.18   1 50.833  ? 11  ILE A HG13 1 c 
ATOM   150  H HG21 . ILE A 1 11  ? -38.058 -0.182  -4.113  1 49.963  ? 11  ILE A HG21 1 c 
ATOM   151  H HG22 . ILE A 1 11  ? -37.265 -1.307  -4.902  1 49.945  ? 11  ILE A HG22 1 c 
ATOM   152  H HG23 . ILE A 1 11  ? -37.198 0.201   -5.388  1 49.955  ? 11  ILE A HG23 1 c 
ATOM   153  H HD11 . ILE A 1 11  ? -37.257 -0.376  -1.396  1 49.629  ? 11  ILE A HD11 1 c 
ATOM   154  H HD12 . ILE A 1 11  ? -36.83  -1.841  -0.94   1 49.628  ? 11  ILE A HD12 1 c 
ATOM   155  H HD13 . ILE A 1 11  ? -37.857 -1.649  -2.141  1 49.719  ? 11  ILE A HD13 1 c 
ATOM   156  N N    . SER A 1 12  ? -32.352 -0.276  -4.151  1 58.518  ? 12  SER A N    1 ? 
ATOM   157  C CA   . SER A 1 12  ? -31.093 -0.105  -3.437  1 56.056  ? 12  SER A CA   1 ? 
ATOM   158  C C    . SER A 1 12  ? -30.307 1.078   -3.996  1 55.015  ? 12  SER A C    1 ? 
ATOM   159  O O    . SER A 1 12  ? -29.851 1.916   -3.23   1 52.799  ? 12  SER A O    1 ? 
ATOM   160  C CB   . SER A 1 12  ? -30.237 -1.366  -3.47   1 58.846  ? 12  SER A CB   1 ? 
ATOM   161  O OG   . SER A 1 12  ? -28.941 -1.145  -2.908  1 51.535  ? 12  SER A OG   1 ? 
ATOM   162  H H    . SER A 1 12  ? -32.341 -0.767  -4.919  1 57.027  ? 12  SER A H    1 c 
ATOM   163  H HA   . SER A 1 12  ? -31.3   0.092   -2.489  1 56.809  ? 12  SER A HA   1 c 
ATOM   164  H HB2  . SER A 1 12  ? -30.688 -2.073  -2.971  1 56.379  ? 12  SER A HB2  1 c 
ATOM   165  H HB3  . SER A 1 12  ? -30.14  -1.664  -4.395  1 56.322  ? 12  SER A HB3  1 c 
ATOM   166  N N    . ARG A 1 13  ? -30.091 1.096   -5.32   1 55.766  ? 13  ARG A N    1 ? 
ATOM   167  C CA   . ARG A 1 13  ? -29.35  2.16    -5.979  1 55.404  ? 13  ARG A CA   1 ? 
ATOM   168  C C    . ARG A 1 13  ? -30.17  3.454   -6.095  1 60.517  ? 13  ARG A C    1 ? 
ATOM   169  O O    . ARG A 1 13  ? -29.652 4.486   -6.525  1 52.367  ? 13  ARG A O    1 ? 
ATOM   170  C CB   . ARG A 1 13  ? -28.905 1.717   -7.38   1 59.593  ? 13  ARG A CB   1 ? 
ATOM   171  C CG   . ARG A 1 13  ? -27.683 0.811   -7.465  1 63.125  ? 13  ARG A CG   1 ? 
ATOM   172  C CD   . ARG A 1 13  ? -27.811 -0.495  -6.698  1 60.244  ? 13  ARG A CD   1 ? 
ATOM   173  N NE   . ARG A 1 13  ? -26.745 -1.388  -7.152  1 62.948  ? 13  ARG A NE   1 ? 
ATOM   174  C CZ   . ARG A 1 13  ? -26.774 -2.176  -8.23   1 61.37   ? 13  ARG A CZ   1 ? 
ATOM   175  N NH1  . ARG A 1 13  ? -27.927 -2.46   -8.799  1 61.858  ? 13  ARG A NH1  1 ? 
ATOM   176  N NH2  . ARG A 1 13  ? -25.658 -2.744  -8.68   1 56.948  ? 13  ARG A NH2  1 ? 
ATOM   177  H H    . ARG A 1 13  ? -30.419 0.411   -5.829  1 55.525  ? 13  ARG A H    1 c 
ATOM   178  H HA   . ARG A 1 13  ? -28.537 2.351   -5.445  1 57.093  ? 13  ARG A HA   1 c 
ATOM   179  H HB2  . ARG A 1 13  ? -29.658 1.259   -7.807  1 59.246  ? 13  ARG A HB2  1 c 
ATOM   180  H HB3  . ARG A 1 13  ? -28.72  2.52    -7.912  1 59.336  ? 13  ARG A HB3  1 c 
ATOM   181  H HG2  . ARG A 1 13  ? -27.51  0.606   -8.408  1 61.681  ? 13  ARG A HG2  1 c 
ATOM   182  H HG3  . ARG A 1 13  ? -26.903 1.301   -7.125  1 61.659  ? 13  ARG A HG3  1 c 
ATOM   183  H HD2  . ARG A 1 13  ? -27.716 -0.332  -5.737  1 61.467  ? 13  ARG A HD2  1 c 
ATOM   184  H HD3  . ARG A 1 13  ? -28.682 -0.907  -6.859  1 61.281  ? 13  ARG A HD3  1 c 
ATOM   185  H HE   . ARG A 1 13  ? -26.019 -1.413  -6.672  1 61.909  ? 13  ARG A HE   1 c 
ATOM   186  H HH11 . ARG A 1 13  ? -28.474 -3.041  -8.42   1 61.675  ? 13  ARG A HH11 1 c 
ATOM   187  H HH12 . ARG A 1 13  ? -28.146 -2.065  -9.558  1 61.57   ? 13  ARG A HH12 1 c 
ATOM   188  H HH21 . ARG A 1 13  ? -24.887 -2.32   -8.599  1 58.28   ? 13  ARG A HH21 1 c 
ATOM   189  H HH22 . ARG A 1 13  ? -25.693 -3.542  -9.059  1 58.299  ? 13  ARG A HH22 1 c 
ATOM   190  N N    . LYS A 1 14  ? -31.463 3.399   -5.771  1 59.016  ? 14  LYS A N    1 ? 
ATOM   191  C CA   . LYS A 1 14  ? -32.324 4.551   -5.935  1 67.807  ? 14  LYS A CA   1 ? 
ATOM   192  C C    . LYS A 1 14  ? -33.457 4.449   -4.93   1 66.952  ? 14  LYS A C    1 ? 
ATOM   193  O O    . LYS A 1 14  ? -34.104 3.412   -4.841  1 72.497  ? 14  LYS A O    1 ? 
ATOM   194  C CB   . LYS A 1 14  ? -32.878 4.595   -7.364  1 78.07   ? 14  LYS A CB   1 ? 
ATOM   195  C CG   . LYS A 1 14  ? -33.945 5.662   -7.617  1 75.391  ? 14  LYS A CG   1 ? 
ATOM   196  C CD   . LYS A 1 14  ? -33.455 7.06    -7.266  1 77.9    ? 14  LYS A CD   1 ? 
ATOM   197  C CE   . LYS A 1 14  ? -34.359 8.132   -7.769  1 81.02   ? 14  LYS A CE   1 ? 
ATOM   198  N NZ   . LYS A 1 14  ? -33.673 9.426   -7.759  1 81.031  ? 14  LYS A NZ   1 ? 
ATOM   199  H H    . LYS A 1 14  ? -31.833 2.619   -5.474  1 61.185  ? 14  LYS A H    1 c 
ATOM   200  H HA   . LYS A 1 14  ? -31.8   5.372   -5.753  1 67.41   ? 14  LYS A HA   1 c 
ATOM   201  H HB2  . LYS A 1 14  ? -32.133 4.752   -7.983  1 75.011  ? 14  LYS A HB2  1 c 
ATOM   202  H HB3  . LYS A 1 14  ? -33.261 3.718   -7.578  1 75.011  ? 14  LYS A HB3  1 c 
ATOM   203  H HG2  . LYS A 1 14  ? -34.198 5.636   -8.565  1 76.445  ? 14  LYS A HG2  1 c 
ATOM   204  H HG3  . LYS A 1 14  ? -34.744 5.453   -7.086  1 76.484  ? 14  LYS A HG3  1 c 
ATOM   205  H HD2  . LYS A 1 14  ? -33.379 7.144   -6.294  1 77.829  ? 14  LYS A HD2  1 c 
ATOM   206  H HD3  . LYS A 1 14  ? -32.561 7.187   -7.65   1 78.013  ? 14  LYS A HD3  1 c 
ATOM   207  H HE2  . LYS A 1 14  ? -34.643 7.929   -8.678  1 80.245  ? 14  LYS A HE2  1 c 
ATOM   208  H HE3  . LYS A 1 14  ? -35.151 8.186   -7.205  1 80.286  ? 14  LYS A HE3  1 c 
ATOM   209  H HZ1  . LYS A 1 14  ? -32.948 9.393   -8.298  1 80.98   ? 14  LYS A HZ1  1 c 
ATOM   210  H HZ2  . LYS A 1 14  ? -33.405 9.623   -6.916  1 80.986  ? 14  LYS A HZ2  1 c 
ATOM   211  H HZ3  . LYS A 1 14  ? -34.234 10.071  -8.046  1 80.946  ? 14  LYS A HZ3  1 c 
ATOM   212  N N    . HIS A 1 15  ? -33.687 5.534   -4.19   1 65.949  ? 15  HIS A N    1 ? 
ATOM   213  C CA   . HIS A 1 15  ? -34.707 5.555   -3.159  1 66.436  ? 15  HIS A CA   1 ? 
ATOM   214  C C    . HIS A 1 15  ? -36.082 5.714   -3.816  1 61.26   ? 15  HIS A C    1 ? 
ATOM   215  O O    . HIS A 1 15  ? -36.236 6.484   -4.763  1 56.543  ? 15  HIS A O    1 ? 
ATOM   216  C CB   . HIS A 1 15  ? -34.34  6.612   -2.112  1 71.978  ? 15  HIS A CB   1 ? 
ATOM   217  C CG   . HIS A 1 15  ? -35.455 7.002   -1.211  1 77.586  ? 15  HIS A CG   1 ? 
ATOM   218  N ND1  . HIS A 1 15  ? -35.95  6.188   -0.215  1 79.248  ? 15  HIS A ND1  1 ? 
ATOM   219  C CD2  . HIS A 1 15  ? -36.183 8.127   -1.181  1 81.586  ? 15  HIS A CD2  1 ? 
ATOM   220  C CE1  . HIS A 1 15  ? -36.933 6.822   0.412   1 83.273  ? 15  HIS A CE1  1 ? 
ATOM   221  N NE2  . HIS A 1 15  ? -37.092 8.005   -0.159  1 84.232  ? 15  HIS A NE2  1 ? 
ATOM   222  H H    . HIS A 1 15  ? -33.178 6.282   -4.317  1 66.493  ? 15  HIS A H    1 c 
ATOM   223  H HA   . HIS A 1 15  ? -34.682 4.677   -2.703  1 66.267  ? 15  HIS A HA   1 c 
ATOM   224  H HB2  . HIS A 1 15  ? -33.599 6.268   -1.567  1 71.934  ? 15  HIS A HB2  1 c 
ATOM   225  H HB3  . HIS A 1 15  ? -34.017 7.415   -2.575  1 71.904  ? 15  HIS A HB3  1 c 
ATOM   226  H HD2  . HIS A 1 15  ? -36.082 8.874   -1.738  1 81.18   ? 15  HIS A HD2  1 c 
ATOM   227  H HE1  . HIS A 1 15  ? -37.436 6.483   1.133   1 82.486  ? 15  HIS A HE1  1 c 
ATOM   228  N N    . TYR A 1 16  ? -37.054 4.958   -3.285  1 57.986  ? 16  TYR A N    1 ? 
ATOM   229  C CA   . TYR A 1 16  ? -38.439 4.938   -3.718  1 57.025  ? 16  TYR A CA   1 ? 
ATOM   230  C C    . TYR A 1 16  ? -39.298 5.123   -2.468  1 61.335  ? 16  TYR A C    1 ? 
ATOM   231  O O    . TYR A 1 16  ? -39.068 4.421   -1.482  1 58.289  ? 16  TYR A O    1 ? 
ATOM   232  C CB   . TYR A 1 16  ? -38.866 3.595   -4.334  1 61.186  ? 16  TYR A CB   1 ? 
ATOM   233  C CG   . TYR A 1 16  ? -38.397 3.277   -5.752  1 60.756  ? 16  TYR A CG   1 ? 
ATOM   234  C CD1  . TYR A 1 16  ? -37.051 3.089   -6.043  1 51.202  ? 16  TYR A CD1  1 ? 
ATOM   235  C CD2  . TYR A 1 16  ? -39.309 3.104   -6.791  1 59.053  ? 16  TYR A CD2  1 ? 
ATOM   236  C CE1  . TYR A 1 16  ? -36.62  2.823   -7.336  1 49.642  ? 16  TYR A CE1  1 ? 
ATOM   237  C CE2  . TYR A 1 16  ? -38.892 2.803   -8.078  1 55.237  ? 16  TYR A CE2  1 ? 
ATOM   238  C CZ   . TYR A 1 16  ? -37.543 2.657   -8.353  1 48.596  ? 16  TYR A CZ   1 ? 
ATOM   239  O OH   . TYR A 1 16  ? -37.125 2.362   -9.628  1 46.933  ? 16  TYR A OH   1 ? 
ATOM   240  H H    . TYR A 1 16  ? -36.829 4.407   -2.591  1 58.658  ? 16  TYR A H    1 c 
ATOM   241  H HA   . TYR A 1 16  ? -38.609 5.676   -4.361  1 58.717  ? 16  TYR A HA   1 c 
ATOM   242  H HB2  . TYR A 1 16  ? -38.552 2.878   -3.739  1 60.108  ? 16  TYR A HB2  1 c 
ATOM   243  H HB3  . TYR A 1 16  ? -39.847 3.558   -4.324  1 60.067  ? 16  TYR A HB3  1 c 
ATOM   244  H HD1  . TYR A 1 16  ? -36.414 3.21    -5.361  1 53.065  ? 16  TYR A HD1  1 c 
ATOM   245  H HD2  . TYR A 1 16  ? -40.231 3.206   -6.619  1 58.351  ? 16  TYR A HD2  1 c 
ATOM   246  H HE1  . TYR A 1 16  ? -35.701 2.71    -7.512  1 49.894  ? 16  TYR A HE1  1 c 
ATOM   247  H HE2  . TYR A 1 16  ? -39.526 2.706   -8.768  1 54.443  ? 16  TYR A HE2  1 c 
ATOM   248  N N    . THR A 1 17  ? -40.278 6.044   -2.52   1 58.891  ? 17  THR A N    1 ? 
ATOM   249  C CA   . THR A 1 17  ? -41.277 6.178   -1.467  1 58.674  ? 17  THR A CA   1 ? 
ATOM   250  C C    . THR A 1 17  ? -42.221 4.982   -1.548  1 58.997  ? 17  THR A C    1 ? 
ATOM   251  O O    . THR A 1 17  ? -42.416 4.405   -2.619  1 70.709  ? 17  THR A O    1 ? 
ATOM   252  C CB   . THR A 1 17  ? -42.074 7.489   -1.562  1 62.007  ? 17  THR A CB   1 ? 
ATOM   253  O OG1  . THR A 1 17  ? -42.814 7.464   -2.784  1 56.361  ? 17  THR A OG1  1 ? 
ATOM   254  C CG2  . THR A 1 17  ? -41.213 8.742   -1.471  1 60.673  ? 17  THR A CG2  1 ? 
ATOM   255  H H    . THR A 1 17  ? -40.324 6.608   -3.239  1 59.44   ? 17  THR A H    1 c 
ATOM   256  H HA   . THR A 1 17  ? -40.816 6.159   -0.6    1 59.35   ? 17  THR A HA   1 c 
ATOM   257  H HB   . THR A 1 17  ? -42.713 7.516   -0.81   1 60.014  ? 17  THR A HB   1 c 
ATOM   258  H HG21 . THR A 1 17  ? -41.78  9.53    -1.511  1 61.058  ? 17  THR A HG21 1 c 
ATOM   259  H HG22 . THR A 1 17  ? -40.584 8.759   -2.212  1 61.041  ? 17  THR A HG22 1 c 
ATOM   260  H HG23 . THR A 1 17  ? -40.723 8.739   -0.632  1 61.058  ? 17  THR A HG23 1 c 
ATOM   261  N N    . VAL A 1 18  ? -42.857 4.66    -0.421  1 52.203  ? 18  VAL A N    1 ? 
ATOM   262  C CA   . VAL A 1 18  ? -43.865 3.615   -0.404  1 59.182  ? 18  VAL A CA   1 ? 
ATOM   263  C C    . VAL A 1 18  ? -45.014 3.978   -1.36   1 65.967  ? 18  VAL A C    1 ? 
ATOM   264  O O    . VAL A 1 18  ? -45.686 3.088   -1.883  1 62.909  ? 18  VAL A O    1 ? 
ATOM   265  C CB   . VAL A 1 18  ? -44.303 3.355   1.052   1 64.543  ? 18  VAL A CB   1 ? 
ATOM   266  C CG1  . VAL A 1 18  ? -44.709 4.635   1.778   1 73.26   ? 18  VAL A CG1  1 ? 
ATOM   267  C CG2  . VAL A 1 18  ? -45.393 2.291   1.167   1 69.669  ? 18  VAL A CG2  1 ? 
ATOM   268  H H    . VAL A 1 18  ? -42.64  5.089   0.355   1 55.605  ? 18  VAL A H    1 c 
ATOM   269  H HA   . VAL A 1 18  ? -43.448 2.797   -0.738  1 59.904  ? 18  VAL A HA   1 c 
ATOM   270  H HB   . VAL A 1 18  ? -43.513 3.001   1.524   1 65.98   ? 18  VAL A HB   1 c 
ATOM   271  H HG11 . VAL A 1 18  ? -45.002 5.301   1.134   1 70.355  ? 18  VAL A HG11 1 c 
ATOM   272  H HG12 . VAL A 1 18  ? -43.949 4.981   2.274   1 70.448  ? 18  VAL A HG12 1 c 
ATOM   273  H HG13 . VAL A 1 18  ? -45.434 4.445   2.396   1 70.507  ? 18  VAL A HG13 1 c 
ATOM   274  H HG21 . VAL A 1 18  ? -45.394 1.922   2.066   1 68.118  ? 18  VAL A HG21 1 c 
ATOM   275  H HG22 . VAL A 1 18  ? -45.222 1.58    0.526   1 68.118  ? 18  VAL A HG22 1 c 
ATOM   276  H HG23 . VAL A 1 18  ? -46.259 2.691   0.981   1 68.111  ? 18  VAL A HG23 1 c 
ATOM   277  N N    . GLU A 1 19  ? -45.222 5.281   -1.627  1 67.944  ? 19  GLU A N    1 ? 
ATOM   278  C CA   . GLU A 1 19  ? -46.326 5.716   -2.474  1 70.85   ? 19  GLU A CA   1 ? 
ATOM   279  C C    . GLU A 1 19  ? -45.988 5.45    -3.941  1 59.493  ? 19  GLU A C    1 ? 
ATOM   280  O O    . GLU A 1 19  ? -46.841 4.996   -4.692  1 54.195  ? 19  GLU A O    1 ? 
ATOM   281  C CB   . GLU A 1 19  ? -46.717 7.191   -2.309  1 74.546  ? 19  GLU A CB   1 ? 
ATOM   282  C CG   . GLU A 1 19  ? -47.408 7.51    -0.984  1 77.294  ? 19  GLU A CG   1 ? 
ATOM   283  C CD   . GLU A 1 19  ? -46.523 7.898   0.195   1 82.116  ? 19  GLU A CD   1 ? 
ATOM   284  O OE1  . GLU A 1 19  ? -45.334 8.281   0.04    1 72.547  ? 19  GLU A OE1  1 ? 
ATOM   285  O OE2  . GLU A 1 19  ? -47.067 7.798   1.317   1 84.676  ? 19  GLU A OE2  1 ? 
ATOM   286  H H    . GLU A 1 19  ? -44.697 5.92    -1.239  1 67.849  ? 19  GLU A H    1 c 
ATOM   287  H HA   . GLU A 1 19  ? -47.123 5.174   -2.242  1 68.702  ? 19  GLU A HA   1 c 
ATOM   288  H HB2  . GLU A 1 19  ? -45.912 7.742   -2.401  1 74.269  ? 19  GLU A HB2  1 c 
ATOM   289  H HB3  . GLU A 1 19  ? -47.328 7.437   -3.035  1 74.21   ? 19  GLU A HB3  1 c 
ATOM   290  H HG2  . GLU A 1 19  ? -48.043 8.242   -1.136  1 77.72   ? 19  GLU A HG2  1 c 
ATOM   291  H HG3  . GLU A 1 19  ? -47.94  6.73    -0.716  1 77.67   ? 19  GLU A HG3  1 c 
ATOM   292  N N    . THR A 1 20  ? -44.759 5.777   -4.347  1 53.924  ? 20  THR A N    1 ? 
ATOM   293  C CA   . THR A 1 20  ? -44.281 5.451   -5.678  1 57.688  ? 20  THR A CA   1 ? 
ATOM   294  C C    . THR A 1 20  ? -44.419 3.942   -5.924  1 61.432  ? 20  THR A C    1 ? 
ATOM   295  O O    . THR A 1 20  ? -44.964 3.534   -6.955  1 55.103  ? 20  THR A O    1 ? 
ATOM   296  C CB   . THR A 1 20  ? -42.844 5.942   -5.831  1 56.87   ? 20  THR A CB   1 ? 
ATOM   297  O OG1  . THR A 1 20  ? -42.864 7.349   -5.622  1 60.351  ? 20  THR A OG1  1 ? 
ATOM   298  C CG2  . THR A 1 20  ? -42.278 5.689   -7.214  1 56.856  ? 20  THR A CG2  1 ? 
ATOM   299  H H    . THR A 1 20  ? -44.204 6.231   -3.78   1 56.214  ? 20  THR A H    1 c 
ATOM   300  H HA   . THR A 1 20  ? -44.841 5.926   -6.329  1 57.439  ? 20  THR A HA   1 c 
ATOM   301  H HB   . THR A 1 20  ? -42.267 5.515   -5.153  1 57.681  ? 20  THR A HB   1 c 
ATOM   302  H HG21 . THR A 1 20  ? -41.549 6.308   -7.386  1 56.89   ? 20  THR A HG21 1 c 
ATOM   303  H HG22 . THR A 1 20  ? -42.975 5.817   -7.879  1 56.885  ? 20  THR A HG22 1 c 
ATOM   304  H HG23 . THR A 1 20  ? -41.945 4.777   -7.267  1 56.889  ? 20  THR A HG23 1 c 
ATOM   305  N N    . LEU A 1 21  ? -44.011 3.123   -4.942  1 54.254  ? 21  LEU A N    1 ? 
ATOM   306  C CA   . LEU A 1 21  ? -44.046 1.674   -5.096  1 55.786  ? 21  LEU A CA   1 ? 
ATOM   307  C C    . LEU A 1 21  ? -45.501 1.206   -5.165  1 55.566  ? 21  LEU A C    1 ? 
ATOM   308  O O    . LEU A 1 21  ? -45.822 0.277   -5.911  1 60.239  ? 21  LEU A O    1 ? 
ATOM   309  C CB   . LEU A 1 21  ? -43.26  0.97    -3.983  1 52.622  ? 21  LEU A CB   1 ? 
ATOM   310  C CG   . LEU A 1 21  ? -41.751 1.26    -3.923  1 55.325  ? 21  LEU A CG   1 ? 
ATOM   311  C CD1  . LEU A 1 21  ? -41.168 0.783   -2.599  1 55.13   ? 21  LEU A CD1  1 ? 
ATOM   312  C CD2  . LEU A 1 21  ? -40.945 0.639   -5.057  1 55.578  ? 21  LEU A CD2  1 ? 
ATOM   313  H H    . LEU A 1 21  ? -43.694 3.475   -4.161  1 56.207  ? 21  LEU A H    1 c 
ATOM   314  H HA   . LEU A 1 21  ? -43.62  1.455   -5.964  1 54.894  ? 21  LEU A HA   1 c 
ATOM   315  H HB2  . LEU A 1 21  ? -43.659 1.225   -3.119  1 53.95   ? 21  LEU A HB2  1 c 
ATOM   316  H HB3  . LEU A 1 21  ? -43.384 -0.001  -4.088  1 53.938  ? 21  LEU A HB3  1 c 
ATOM   317  H HG   . LEU A 1 21  ? -41.63  2.241   -3.969  1 54.93   ? 21  LEU A HG   1 c 
ATOM   318  H HD11 . LEU A 1 21  ? -41.633 1.216   -1.863  1 55.179  ? 21  LEU A HD11 1 c 
ATOM   319  H HD12 . LEU A 1 21  ? -40.223 1.009   -2.56   1 55.185  ? 21  LEU A HD12 1 c 
ATOM   320  H HD13 . LEU A 1 21  ? -41.273 -0.18   -2.525  1 55.184  ? 21  LEU A HD13 1 c 
ATOM   321  H HD21 . LEU A 1 21  ? -41.289 0.953   -5.91   1 55.49   ? 21  LEU A HD21 1 c 
ATOM   322  H HD22 . LEU A 1 21  ? -41.018 -0.329  -5.016  1 55.493  ? 21  LEU A HD22 1 c 
ATOM   323  H HD23 . LEU A 1 21  ? -40.012 0.897   -4.971  1 55.463  ? 21  LEU A HD23 1 c 
ATOM   324  N N    . LYS A 1 22  ? -46.396 1.86    -4.421  1 57.183  ? 22  LYS A N    1 ? 
ATOM   325  C CA   . LYS A 1 22  ? -47.809 1.486   -4.468  1 62.975  ? 22  LYS A CA   1 ? 
ATOM   326  C C    . LYS A 1 22  ? -48.404 1.774   -5.847  1 52.629  ? 22  LYS A C    1 ? 
ATOM   327  O O    . LYS A 1 22  ? -49.156 0.96    -6.38   1 50.821  ? 22  LYS A O    1 ? 
ATOM   328  C CB   . LYS A 1 22  ? -48.606 2.143   -3.338  1 68.547  ? 22  LYS A CB   1 ? 
ATOM   329  C CG   . LYS A 1 22  ? -48.44  1.413   -2.016  1 72.602  ? 22  LYS A CG   1 ? 
ATOM   330  C CD   . LYS A 1 22  ? -48.963 2.146   -0.788  1 75.115  ? 22  LYS A CD   1 ? 
ATOM   331  C CE   . LYS A 1 22  ? -49.138 1.197   0.354   1 79.032  ? 22  LYS A CE   1 ? 
ATOM   332  N NZ   . LYS A 1 22  ? -49.647 1.881   1.542   1 81.874  ? 22  LYS A NZ   1 ? 
ATOM   333  H H    . LYS A 1 22  ? -46.131 2.531   -3.86   1 58.131  ? 22  LYS A H    1 c 
ATOM   334  H HA   . LYS A 1 22  ? -47.864 0.507   -4.319  1 60.777  ? 22  LYS A HA   1 c 
ATOM   335  H HB2  . LYS A 1 22  ? -48.311 3.072   -3.228  1 68.047  ? 22  LYS A HB2  1 c 
ATOM   336  H HB3  . LYS A 1 22  ? -49.558 2.152   -3.576  1 68.027  ? 22  LYS A HB3  1 c 
ATOM   337  H HG2  . LYS A 1 22  ? -48.902 0.549   -2.086  1 72.274  ? 22  LYS A HG2  1 c 
ATOM   338  H HG3  . LYS A 1 22  ? -47.487 1.222   -1.886  1 72.168  ? 22  LYS A HG3  1 c 
ATOM   339  H HD2  . LYS A 1 22  ? -48.328 2.85    -0.532  1 75.423  ? 22  LYS A HD2  1 c 
ATOM   340  H HD3  . LYS A 1 22  ? -49.826 2.564   -0.999  1 75.423  ? 22  LYS A HD3  1 c 
ATOM   341  H HE2  . LYS A 1 22  ? -49.763 0.493   0.103   1 78.732  ? 22  LYS A HE2  1 c 
ATOM   342  H HE3  . LYS A 1 22  ? -48.283 0.783   0.568   1 78.767  ? 22  LYS A HE3  1 c 
ATOM   343  H HZ1  . LYS A 1 22  ? -50.465 2.229   1.369   1 80.981  ? 22  LYS A HZ1  1 c 
ATOM   344  H HZ2  . LYS A 1 22  ? -49.083 2.551   1.776   1 80.954  ? 22  LYS A HZ2  1 c 
ATOM   345  H HZ3  . LYS A 1 22  ? -49.712 1.294   2.229   1 80.981  ? 22  LYS A HZ3  1 c 
ATOM   346  N N    . SER A 1 23  ? -48.012 2.899   -6.451  1 51.966  ? 23  SER A N    1 ? 
ATOM   347  C CA   . SER A 1 23  ? -48.506 3.255   -7.773  1 55.366  ? 23  SER A CA   1 ? 
ATOM   348  C C    . SER A 1 23  ? -47.943 2.298   -8.825  1 53.937  ? 23  SER A C    1 ? 
ATOM   349  O O    . SER A 1 23  ? -48.587 2.02    -9.84   1 51.97   ? 23  SER A O    1 ? 
ATOM   350  C CB   . SER A 1 23  ? -48.191 4.687   -8.092  1 58.635  ? 23  SER A CB   1 ? 
ATOM   351  O OG   . SER A 1 23  ? -48.708 5.553   -7.087  1 58.736  ? 23  SER A OG   1 ? 
ATOM   352  H H    . SER A 1 23  ? -47.435 3.467   -6.028  1 52.999  ? 23  SER A H    1 c 
ATOM   353  H HA   . SER A 1 23  ? -49.492 3.154   -7.767  1 54.981  ? 23  SER A HA   1 c 
ATOM   354  H HB2  . SER A 1 23  ? -47.225 4.799   -8.152  1 57.89   ? 23  SER A HB2  1 c 
ATOM   355  H HB3  . SER A 1 23  ? -48.582 4.92    -8.956  1 57.896  ? 23  SER A HB3  1 c 
ATOM   356  N N    . LEU A 1 24  ? -46.736 1.78    -8.576  1 53.528  ? 24  LEU A N    1 ? 
ATOM   357  C CA   . LEU A 1 24  ? -46.112 0.865   -9.516  1 47.646  ? 24  LEU A CA   1 ? 
ATOM   358  C C    . LEU A 1 24  ? -46.847 -0.47   -9.475  1 45.991  ? 24  LEU A C    1 ? 
ATOM   359  O O    . LEU A 1 24  ? -47.258 -0.983  -10.512 1 47.145  ? 24  LEU A O    1 ? 
ATOM   360  C CB   . LEU A 1 24  ? -44.623 0.772   -9.225  1 47.31   ? 24  LEU A CB   1 ? 
ATOM   361  C CG   . LEU A 1 24  ? -43.818 2.003   -9.639  1 46.348  ? 24  LEU A CG   1 ? 
ATOM   362  C CD1  . LEU A 1 24  ? -42.372 1.912   -9.19   1 53.22   ? 24  LEU A CD1  1 ? 
ATOM   363  C CD2  . LEU A 1 24  ? -43.9   2.232   -11.135 1 53.341  ? 24  LEU A CD2  1 ? 
ATOM   364  H H    . LEU A 1 24  ? -46.279 2.02    -7.823  1 52.195  ? 24  LEU A H    1 c 
ATOM   365  H HA   . LEU A 1 24  ? -46.232 1.238   -10.425 1 48.436  ? 24  LEU A HA   1 c 
ATOM   366  H HB2  . LEU A 1 24  ? -44.502 0.626   -8.259  1 47.285  ? 24  LEU A HB2  1 c 
ATOM   367  H HB3  . LEU A 1 24  ? -44.263 -0.012  -9.7    1 47.207  ? 24  LEU A HB3  1 c 
ATOM   368  H HG   . LEU A 1 24  ? -44.22  2.793   -9.199  1 49.055  ? 24  LEU A HG   1 c 
ATOM   369  H HD11 . LEU A 1 24  ? -42.339 1.654   -8.253  1 51.075  ? 24  LEU A HD11 1 c 
ATOM   370  H HD12 . LEU A 1 24  ? -41.942 2.776   -9.302  1 51.124  ? 24  LEU A HD12 1 c 
ATOM   371  H HD13 . LEU A 1 24  ? -41.908 1.247   -9.724  1 51.124  ? 24  LEU A HD13 1 c 
ATOM   372  H HD21 . LEU A 1 24  ? -44.671 2.789   -11.336 1 51.118  ? 24  LEU A HD21 1 c 
ATOM   373  H HD22 . LEU A 1 24  ? -43.991 1.381   -11.59  1 51.032  ? 24  LEU A HD22 1 c 
ATOM   374  H HD23 . LEU A 1 24  ? -43.093 2.678   -11.444 1 51.145  ? 24  LEU A HD23 1 c 
ATOM   375  N N    . VAL A 1 25  ? -47.12  -0.946  -8.264  1 49.653  ? 25  VAL A N    1 ? 
ATOM   376  C CA   . VAL A 1 25  ? -47.903 -2.155  -8.058  1 50.126  ? 25  VAL A CA   1 ? 
ATOM   377  C C    . VAL A 1 25  ? -49.317 -2.007  -8.627  1 53.589  ? 25  VAL A C    1 ? 
ATOM   378  O O    . VAL A 1 25  ? -49.84  -2.976  -9.177  1 56.769  ? 25  VAL A O    1 ? 
ATOM   379  C CB   . VAL A 1 25  ? -47.879 -2.519  -6.56   1 45.842  ? 25  VAL A CB   1 ? 
ATOM   380  C CG1  . VAL A 1 25  ? -48.952 -3.516  -6.157  1 47.029  ? 25  VAL A CG1  1 ? 
ATOM   381  C CG2  . VAL A 1 25  ? -46.5   -3.038  -6.159  1 51.183  ? 25  VAL A CG2  1 ? 
ATOM   382  H H    . VAL A 1 25  ? -46.788 -0.511  -7.531  1 48.867  ? 25  VAL A H    1 c 
ATOM   383  H HA   . VAL A 1 25  ? -47.463 -2.876  -8.545  1 49.894  ? 25  VAL A HA   1 c 
ATOM   384  H HB   . VAL A 1 25  ? -48.045 -1.688  -6.055  1 47.806  ? 25  VAL A HB   1 c 
ATOM   385  H HG11 . VAL A 1 25  ? -49.019 -4.214  -6.83   1 46.743  ? 25  VAL A HG11 1 c 
ATOM   386  H HG12 . VAL A 1 25  ? -49.807 -3.061  -6.074  1 46.744  ? 25  VAL A HG12 1 c 
ATOM   387  H HG13 . VAL A 1 25  ? -48.719 -3.915  -5.303  1 46.811  ? 25  VAL A HG13 1 c 
ATOM   388  H HG21 . VAL A 1 25  ? -46.471 -3.177  -5.198  1 49.542  ? 25  VAL A HG21 1 c 
ATOM   389  H HG22 . VAL A 1 25  ? -45.821 -2.39   -6.411  1 49.593  ? 25  VAL A HG22 1 c 
ATOM   390  H HG23 . VAL A 1 25  ? -46.326 -3.88   -6.613  1 49.557  ? 25  VAL A HG23 1 c 
ATOM   391  N N    . ASP A 1 26  ? -49.929 -0.813  -8.519  1 59.337  ? 26  ASP A N    1 ? 
ATOM   392  C CA   . ASP A 1 26  ? -51.216 -0.549  -9.164  1 54.786  ? 26  ASP A CA   1 ? 
ATOM   393  C C    . ASP A 1 26  ? -51.156 -0.904  -10.646 1 45.459  ? 26  ASP A C    1 ? 
ATOM   394  O O    . ASP A 1 26  ? -51.964 -1.688  -11.128 1 46.027  ? 26  ASP A O    1 ? 
ATOM   395  C CB   . ASP A 1 26  ? -51.667 0.9     -9.024  1 55.712  ? 26  ASP A CB   1 ? 
ATOM   396  C CG   . ASP A 1 26  ? -52.254 1.27    -7.668  1 72.314  ? 26  ASP A CG   1 ? 
ATOM   397  O OD1  . ASP A 1 26  ? -52.453 0.356   -6.853  1 74.627  ? 26  ASP A OD1  1 ? 
ATOM   398  O OD2  . ASP A 1 26  ? -52.524 2.474   -7.443  1 89.742  ? 26  ASP A OD2  1 ? 
ATOM   399  H H    . ASP A 1 26  ? -49.543 -0.15   -8.022  1 56.78   ? 26  ASP A H    1 c 
ATOM   400  H HA   . ASP A 1 26  ? -51.892 -1.125  -8.743  1 54.049  ? 26  ASP A HA   1 c 
ATOM   401  H HB2  . ASP A 1 26  ? -50.908 1.491   -9.191  1 58.898  ? 26  ASP A HB2  1 c 
ATOM   402  H HB3  . ASP A 1 26  ? -52.349 1.092   -9.702  1 58.866  ? 26  ASP A HB3  1 c 
ATOM   403  N N    . GLU A 1 27  ? -50.17  -0.337  -11.344 1 42.305  ? 27  GLU A N    1 ? 
ATOM   404  C CA   . GLU A 1 27  ? -49.992 -0.565  -12.766 1 44.75   ? 27  GLU A CA   1 ? 
ATOM   405  C C    . GLU A 1 27  ? -49.722 -2.053  -13.044 1 48.345  ? 27  GLU A C    1 ? 
ATOM   406  O O    . GLU A 1 27  ? -50.25  -2.601  -14     1 51.571  ? 27  GLU A O    1 ? 
ATOM   407  C CB   . GLU A 1 27  ? -48.896 0.379   -13.26  1 47.144  ? 27  GLU A CB   1 ? 
ATOM   408  C CG   . GLU A 1 27  ? -48.906 0.586   -14.771 1 53.151  ? 27  GLU A CG   1 ? 
ATOM   409  C CD   . GLU A 1 27  ? -50.219 1.174   -15.257 1 55.633  ? 27  GLU A CD   1 ? 
ATOM   410  O OE1  . GLU A 1 27  ? -50.643 0.829   -16.371 1 54.164  ? 27  GLU A OE1  1 ? 
ATOM   411  O OE2  . GLU A 1 27  ? -50.841 1.948   -14.49  1 64.031  ? 27  GLU A OE2  1 ? 
ATOM   412  H H    . GLU A 1 27  ? -49.582 0.213   -10.91  1 43.851  ? 27  GLU A H    1 c 
ATOM   413  H HA   . GLU A 1 27  ? -50.842 -0.329  -13.21  1 45.453  ? 27  GLU A HA   1 c 
ATOM   414  H HB2  . GLU A 1 27  ? -49.004 1.242   -12.815 1 47.946  ? 27  GLU A HB2  1 c 
ATOM   415  H HB3  . GLU A 1 27  ? -48.025 0.015   -12.996 1 47.892  ? 27  GLU A HB3  1 c 
ATOM   416  H HG2  . GLU A 1 27  ? -48.174 1.188   -15.024 1 52.28   ? 27  GLU A HG2  1 c 
ATOM   417  H HG3  . GLU A 1 27  ? -48.76  -0.276  -15.218 1 52.282  ? 27  GLU A HG3  1 c 
ATOM   418  N N    . ILE A 1 28  ? -48.939 -2.726  -12.193 1 52.065  ? 28  ILE A N    1 ? 
ATOM   419  C CA   . ILE A 1 28  ? -48.682 -4.15   -12.359 1 49.772  ? 28  ILE A CA   1 ? 
ATOM   420  C C    . ILE A 1 28  ? -50.001 -4.904  -12.245 1 52.277  ? 28  ILE A C    1 ? 
ATOM   421  O O    . ILE A 1 28  ? -50.266 -5.766  -13.086 1 51.754  ? 28  ILE A O    1 ? 
ATOM   422  C CB   . ILE A 1 28  ? -47.647 -4.69   -11.351 1 51.845  ? 28  ILE A CB   1 ? 
ATOM   423  C CG1  . ILE A 1 28  ? -46.288 -4.046  -11.562 1 47.152  ? 28  ILE A CG1  1 ? 
ATOM   424  C CG2  . ILE A 1 28  ? -47.555 -6.219  -11.415 1 50.583  ? 28  ILE A CG2  1 ? 
ATOM   425  C CD1  . ILE A 1 28  ? -45.344 -4.234  -10.394 1 54.832  ? 28  ILE A CD1  1 ? 
ATOM   426  H H    . ILE A 1 28  ? -48.554 -2.288  -11.489 1 50.52   ? 28  ILE A H    1 c 
ATOM   427  H HA   . ILE A 1 28  ? -48.327 -4.289  -13.257 1 51.03   ? 28  ILE A HA   1 c 
ATOM   428  H HB   . ILE A 1 28  ? -47.954 -4.447  -10.455 1 50.356  ? 28  ILE A HB   1 c 
ATOM   429  H HG12 . ILE A 1 28  ? -45.886 -4.438  -12.361 1 49.792  ? 28  ILE A HG12 1 c 
ATOM   430  H HG13 . ILE A 1 28  ? -46.405 -3.09   -11.725 1 49.863  ? 28  ILE A HG13 1 c 
ATOM   431  H HG21 . ILE A 1 28  ? -46.716 -6.515  -11.025 1 50.989  ? 28  ILE A HG21 1 c 
ATOM   432  H HG22 . ILE A 1 28  ? -47.595 -6.505  -12.341 1 51.032  ? 28  ILE A HG22 1 c 
ATOM   433  H HG23 . ILE A 1 28  ? -48.292 -6.614  -10.921 1 51.049  ? 28  ILE A HG23 1 c 
ATOM   434  H HD11 . ILE A 1 28  ? -45.834 -4.18   -9.553  1 52.386  ? 28  ILE A HD11 1 c 
ATOM   435  H HD12 . ILE A 1 28  ? -44.662 -3.536  -10.415 1 52.405  ? 28  ILE A HD12 1 c 
ATOM   436  H HD13 . ILE A 1 28  ? -44.914 -5.107  -10.461 1 52.337  ? 28  ILE A HD13 1 c 
ATOM   437  N N    . SER A 1 29  ? -50.806 -4.6    -11.214 1 47.688  ? 29  SER A N    1 ? 
ATOM   438  C CA   . SER A 1 29  ? -52.06  -5.329  -11.032 1 53.329  ? 29  SER A CA   1 ? 
ATOM   439  C C    . SER A 1 29  ? -53.026 -5.038  -12.175 1 53.103  ? 29  SER A C    1 ? 
ATOM   440  O O    . SER A 1 29  ? -53.688 -5.951  -12.665 1 53.61   ? 29  SER A O    1 ? 
ATOM   441  C CB   . SER A 1 29  ? -52.738 -5.046  -9.722  1 52.779  ? 29  SER A CB   1 ? 
ATOM   442  O OG   . SER A 1 29  ? -53.901 -5.855  -9.615  1 53.646  ? 29  SER A OG   1 ? 
ATOM   443  H H    . SER A 1 29  ? -50.574 -3.948  -10.616 1 50.007  ? 29  SER A H    1 c 
ATOM   444  H HA   . SER A 1 29  ? -51.851 -6.296  -11.059 1 52.144  ? 29  SER A HA   1 c 
ATOM   445  H HB2  . SER A 1 29  ? -52.127 -5.245  -8.988  1 53.216  ? 29  SER A HB2  1 c 
ATOM   446  H HB3  . SER A 1 29  ? -52.986 -4.103  -9.677  1 53.129  ? 29  SER A HB3  1 c 
ATOM   447  N N    . TYR A 1 30  ? -53.062 -3.777  -12.621 1 50.347  ? 30  TYR A N    1 ? 
ATOM   448  C CA   . TYR A 1 30  ? -54.029 -3.351  -13.623 1 54.051  ? 30  TYR A CA   1 ? 
ATOM   449  C C    . TYR A 1 30  ? -53.888 -4.196  -14.886 1 59.098  ? 30  TYR A C    1 ? 
ATOM   450  O O    . TYR A 1 30  ? -54.89  -4.529  -15.518 1 48.992  ? 30  TYR A O    1 ? 
ATOM   451  C CB   . TYR A 1 30  ? -53.851 -1.867  -13.965 1 54.244  ? 30  TYR A CB   1 ? 
ATOM   452  C CG   . TYR A 1 30  ? -54.867 -1.325  -14.953 1 51.212  ? 30  TYR A CG   1 ? 
ATOM   453  C CD1  . TYR A 1 30  ? -56.172 -1.053  -14.548 1 59.997  ? 30  TYR A CD1  1 ? 
ATOM   454  C CD2  . TYR A 1 30  ? -54.53  -1.101  -16.285 1 47.739  ? 30  TYR A CD2  1 ? 
ATOM   455  C CE1  . TYR A 1 30  ? -57.109 -0.541  -15.434 1 58.562  ? 30  TYR A CE1  1 ? 
ATOM   456  C CE2  . TYR A 1 30  ? -55.461 -0.6    -17.181 1 62.603  ? 30  TYR A CE2  1 ? 
ATOM   457  C CZ   . TYR A 1 30  ? -56.748 -0.309  -16.751 1 60.674  ? 30  TYR A CZ   1 ? 
ATOM   458  O OH   . TYR A 1 30  ? -57.666 0.169   -17.632 1 68.67   ? 30  TYR A OH   1 ? 
ATOM   459  H H    . TYR A 1 30  ? -52.478 -3.16   -12.285 1 51.808  ? 30  TYR A H    1 c 
ATOM   460  H HA   . TYR A 1 30  ? -54.943 -3.483  -13.253 1 54.221  ? 30  TYR A HA   1 c 
ATOM   461  H HB2  . TYR A 1 30  ? -53.909 -1.347  -13.133 1 53.483  ? 30  TYR A HB2  1 c 
ATOM   462  H HB3  . TYR A 1 30  ? -52.949 -1.74   -14.335 1 53.448  ? 30  TYR A HB3  1 c 
ATOM   463  H HD1  . TYR A 1 30  ? -56.416 -1.193  -13.647 1 57.499  ? 30  TYR A HD1  1 c 
ATOM   464  H HD2  . TYR A 1 30  ? -53.652 -1.282  -16.58  1 51.909  ? 30  TYR A HD2  1 c 
ATOM   465  H HE1  . TYR A 1 30  ? -57.986 -0.355  -15.143 1 59.325  ? 30  TYR A HE1  1 c 
ATOM   466  H HE2  . TYR A 1 30  ? -55.218 -0.444  -18.078 1 58.328  ? 30  TYR A HE2  1 c 
ATOM   467  N N    . ASN A 1 31  ? -52.634 -4.533  -15.227 1 58.967  ? 31  ASN A N    1 ? 
ATOM   468  C CA   . ASN A 1 31  ? -52.324 -5.217  -16.465 1 56.178  ? 31  ASN A CA   1 ? 
ATOM   469  C C    . ASN A 1 31  ? -52.086 -6.709  -16.251 1 52.908  ? 31  ASN A C    1 ? 
ATOM   470  O O    . ASN A 1 31  ? -51.538 -7.338  -17.134 1 50.641  ? 31  ASN A O    1 ? 
ATOM   471  C CB   . ASN A 1 31  ? -51.107 -4.568  -17.105 1 61.147  ? 31  ASN A CB   1 ? 
ATOM   472  C CG   . ASN A 1 31  ? -51.436 -3.199  -17.633 1 54.414  ? 31  ASN A CG   1 ? 
ATOM   473  O OD1  . ASN A 1 31  ? -52.128 -3.09   -18.649 1 51.511  ? 31  ASN A OD1  1 ? 
ATOM   474  N ND2  . ASN A 1 31  ? -50.92  -2.164  -16.993 1 59.072  ? 31  ASN A ND2  1 ? 
ATOM   475  H H    . ASN A 1 31  ? -51.942 -4.305  -14.677 1 58.246  ? 31  ASN A H    1 c 
ATOM   476  H HA   . ASN A 1 31  ? -53.078 -5.109  -17.087 1 56.929  ? 31  ASN A HA   1 c 
ATOM   477  H HB2  . ASN A 1 31  ? -50.39  -4.498  -16.444 1 58.38   ? 31  ASN A HB2  1 c 
ATOM   478  H HB3  . ASN A 1 31  ? -50.787 -5.124  -17.843 1 58.308  ? 31  ASN A HB3  1 c 
ATOM   479  H HD21 . ASN A 1 31  ? -50.623 -1.464  -17.45  1 57.597  ? 31  ASN A HD21 1 c 
ATOM   480  H HD22 . ASN A 1 31  ? -50.872 -2.171  -16.107 1 57.598  ? 31  ASN A HD22 1 c 
ATOM   481  N N    . GLY A 1 32  ? -52.47  -7.268  -15.093 1 63.929  ? 32  GLY A N    1 ? 
ATOM   482  C CA   . GLY A 1 32  ? -52.451 -8.709  -14.869 1 58.411  ? 32  GLY A CA   1 ? 
ATOM   483  C C    . GLY A 1 32  ? -51.046 -9.289  -14.672 1 57.344  ? 32  GLY A C    1 ? 
ATOM   484  O O    . GLY A 1 32  ? -50.835 -10.446 -14.997 1 64.189  ? 32  GLY A O    1 ? 
ATOM   485  H H    . GLY A 1 32  ? -52.752 -6.733  -14.41  1 59.8    ? 32  GLY A H    1 c 
ATOM   486  H HA2  . GLY A 1 32  ? -52.997 -8.91   -14.073 1 59.423  ? 32  GLY A HA2  1 c 
ATOM   487  H HA3  . GLY A 1 32  ? -52.877 -9.153  -15.64  1 59.355  ? 32  GLY A HA3  1 c 
ATOM   488  N N    . GLY A 1 33  ? -50.094 -8.51   -14.135 1 56.37   ? 33  GLY A N    1 ? 
ATOM   489  C CA   . GLY A 1 33  ? -48.798 -9.029  -13.707 1 60.158  ? 33  GLY A CA   1 ? 
ATOM   490  C C    . GLY A 1 33  ? -48.915 -9.935  -12.472 1 61.263  ? 33  GLY A C    1 ? 
ATOM   491  O O    . GLY A 1 33  ? -49.92  -9.883  -11.768 1 58.439  ? 33  GLY A O    1 ? 
ATOM   492  H H    . GLY A 1 33  ? -50.257 -7.618  -14.028 1 57.487  ? 33  GLY A H    1 c 
ATOM   493  H HA2  . GLY A 1 33  ? -48.395 -9.539  -14.449 1 59.484  ? 33  GLY A HA2  1 c 
ATOM   494  H HA3  . GLY A 1 33  ? -48.202 -8.275  -13.504 1 59.408  ? 33  GLY A HA3  1 c 
ATOM   495  N N    . ASN A 1 34  ? -47.889 -10.766 -12.207 1 52.093  ? 34  ASN A N    1 ? 
ATOM   496  C CA   . ASN A 1 34  ? -48.003 -11.808 -11.191 1 50.377  ? 34  ASN A CA   1 ? 
ATOM   497  C C    . ASN A 1 34  ? -47.226 -11.479 -9.921  1 47.015  ? 34  ASN A C    1 ? 
ATOM   498  O O    . ASN A 1 34  ? -47.663 -11.843 -8.827  1 50.735  ? 34  ASN A O    1 ? 
ATOM   499  C CB   . ASN A 1 34  ? -47.557 -13.149 -11.746 1 52.032  ? 34  ASN A CB   1 ? 
ATOM   500  C CG   . ASN A 1 34  ? -48.315 -13.462 -13.009 1 52.778  ? 34  ASN A CG   1 ? 
ATOM   501  O OD1  . ASN A 1 34  ? -47.737 -13.46  -14.1   1 51.202  ? 34  ASN A OD1  1 ? 
ATOM   502  N ND2  . ASN A 1 34  ? -49.612 -13.675 -12.883 1 53.162  ? 34  ASN A ND2  1 ? 
ATOM   503  H H    . ASN A 1 34  ? -47.115 -10.695 -12.688 1 53.676  ? 34  ASN A H    1 c 
ATOM   504  H HA   . ASN A 1 34  ? -48.95  -11.903 -10.945 1 50.481  ? 34  ASN A HA   1 c 
ATOM   505  H HB2  . ASN A 1 34  ? -46.598 -13.123 -11.937 1 51.817  ? 34  ASN A HB2  1 c 
ATOM   506  H HB3  . ASN A 1 34  ? -47.722 -13.85  -11.084 1 51.82   ? 34  ASN A HB3  1 c 
ATOM   507  H HD21 . ASN A 1 34  ? -50.173 -13.366 -13.497 1 53.042  ? 34  ASN A HD21 1 c 
ATOM   508  H HD22 . ASN A 1 34  ? -49.921 -14.127 -12.185 1 53.036  ? 34  ASN A HD22 1 c 
ATOM   509  N N    . TYR A 1 35  ? -46.092 -10.787 -10.073 1 41.08   ? 35  TYR A N    1 ? 
ATOM   510  C CA   . TYR A 1 35  ? -45.211 -10.532 -8.957  1 40.784  ? 35  TYR A CA   1 ? 
ATOM   511  C C    . TYR A 1 35  ? -44.395 -9.258  -9.144  1 39.989  ? 35  TYR A C    1 ? 
ATOM   512  O O    . TYR A 1 35  ? -44.112 -8.81   -10.255 1 43.628  ? 35  TYR A O    1 ? 
ATOM   513  C CB   . TYR A 1 35  ? -44.247 -11.714 -8.807  1 45.876  ? 35  TYR A CB   1 ? 
ATOM   514  C CG   . TYR A 1 35  ? -43.118 -11.914 -9.817  1 43.362  ? 35  TYR A CG   1 ? 
ATOM   515  C CD1  . TYR A 1 35  ? -41.896 -11.267 -9.663  1 43.687  ? 35  TYR A CD1  1 ? 
ATOM   516  C CD2  . TYR A 1 35  ? -43.205 -12.882 -10.818 1 45.308  ? 35  TYR A CD2  1 ? 
ATOM   517  C CE1  . TYR A 1 35  ? -40.814 -11.538 -10.496 1 47.3    ? 35  TYR A CE1  1 ? 
ATOM   518  C CE2  . TYR A 1 35  ? -42.136 -13.15  -11.665 1 43.8    ? 35  TYR A CE2  1 ? 
ATOM   519  C CZ   . TYR A 1 35  ? -40.934 -12.485 -11.5   1 41.599  ? 35  TYR A CZ   1 ? 
ATOM   520  O OH   . TYR A 1 35  ? -39.888 -12.716 -12.347 1 41.821  ? 35  TYR A OH   1 ? 
ATOM   521  H H    . TYR A 1 35  ? -45.852 -10.476 -10.897 1 42.535  ? 35  TYR A H    1 c 
ATOM   522  H HA   . TYR A 1 35  ? -45.753 -10.45  -8.135  1 41.764  ? 35  TYR A HA   1 c 
ATOM   523  H HB2  . TYR A 1 35  ? -43.841 -11.649 -7.915  1 44.114  ? 35  TYR A HB2  1 c 
ATOM   524  H HB3  . TYR A 1 35  ? -44.787 -12.535 -8.795  1 44.109  ? 35  TYR A HB3  1 c 
ATOM   525  H HD1  . TYR A 1 35  ? -41.79  -10.643 -8.963  1 44.42   ? 35  TYR A HD1  1 c 
ATOM   526  H HD2  . TYR A 1 35  ? -44.009 -13.365 -10.925 1 44.488  ? 35  TYR A HD2  1 c 
ATOM   527  H HE1  . TYR A 1 35  ? -40.007 -11.064 -10.39  1 45.034  ? 35  TYR A HE1  1 c 
ATOM   528  H HE2  . TYR A 1 35  ? -42.228 -13.787 -12.353 1 43.635  ? 35  TYR A HE2  1 c 
ATOM   529  N N    . VAL A 1 36  ? -43.92  -8.748  -8.014  1 35.482  ? 36  VAL A N    1 ? 
ATOM   530  C CA   . VAL A 1 36  ? -42.937 -7.694  -8.037  1 40.761  ? 36  VAL A CA   1 ? 
ATOM   531  C C    . VAL A 1 36  ? -41.746 -8.176  -7.223  1 40.958  ? 36  VAL A C    1 ? 
ATOM   532  O O    . VAL A 1 36  ? -41.9   -8.673  -6.105  1 44.616  ? 36  VAL A O    1 ? 
ATOM   533  C CB   . VAL A 1 36  ? -43.562 -6.382  -7.505  1 46.983  ? 36  VAL A CB   1 ? 
ATOM   534  C CG1  . VAL A 1 36  ? -44.167 -6.53   -6.117  1 50.343  ? 36  VAL A CG1  1 ? 
ATOM   535  C CG2  . VAL A 1 36  ? -42.567 -5.224  -7.533  1 49.88   ? 36  VAL A CG2  1 ? 
ATOM   536  H H    . VAL A 1 36  ? -44.194 -9.085  -7.21   1 37.889  ? 36  VAL A H    1 c 
ATOM   537  H HA   . VAL A 1 36  ? -42.655 -7.548  -8.952  1 40.782  ? 36  VAL A HA   1 c 
ATOM   538  H HB   . VAL A 1 36  ? -44.297 -6.148  -8.119  1 46.883  ? 36  VAL A HB   1 c 
ATOM   539  H HG11 . VAL A 1 36  ? -43.475 -6.762  -5.478  1 49.224  ? 36  VAL A HG11 1 c 
ATOM   540  H HG12 . VAL A 1 36  ? -44.847 -7.223  -6.124  1 49.179  ? 36  VAL A HG12 1 c 
ATOM   541  H HG13 . VAL A 1 36  ? -44.574 -5.687  -5.853  1 49.277  ? 36  VAL A HG13 1 c 
ATOM   542  H HG21 . VAL A 1 36  ? -43.049 -4.381  -7.52   1 48.991  ? 36  VAL A HG21 1 c 
ATOM   543  H HG22 . VAL A 1 36  ? -42.029 -5.277  -8.341  1 48.952  ? 36  VAL A HG22 1 c 
ATOM   544  H HG23 . VAL A 1 36  ? -41.986 -5.276  -6.755  1 48.967  ? 36  VAL A HG23 1 c 
ATOM   545  N N    . GLN A 1 37  ? -40.552 -8.009  -7.778  1 42.819  ? 37  GLN A N    1 ? 
ATOM   546  C CA   . GLN A 1 37  ? -39.347 -8.407  -7.078  1 43.054  ? 37  GLN A CA   1 ? 
ATOM   547  C C    . GLN A 1 37  ? -38.684 -7.157  -6.504  1 43.658  ? 37  GLN A C    1 ? 
ATOM   548  O O    . GLN A 1 37  ? -38.336 -6.235  -7.235  1 45.899  ? 37  GLN A O    1 ? 
ATOM   549  C CB   . GLN A 1 37  ? -38.519 -9.233  -8.053  1 45.289  ? 37  GLN A CB   1 ? 
ATOM   550  C CG   . GLN A 1 37  ? -37.127 -9.621  -7.556  1 46.623  ? 37  GLN A CG   1 ? 
ATOM   551  C CD   . GLN A 1 37  ? -36.322 -10.384 -8.592  1 45.869  ? 37  GLN A CD   1 ? 
ATOM   552  O OE1  . GLN A 1 37  ? -36.864 -11.179 -9.37   1 45.462  ? 37  GLN A OE1  1 ? 
ATOM   553  N NE2  . GLN A 1 37  ? -35.022 -10.119 -8.64   1 41.416  ? 37  GLN A NE2  1 ? 
ATOM   554  H H    . GLN A 1 37  ? -40.479 -7.633  -8.608  1 42.423  ? 37  GLN A H    1 c 
ATOM   555  H HA   . GLN A 1 37  ? -39.598 -9.005  -6.336  1 43.622  ? 37  GLN A HA   1 c 
ATOM   556  H HB2  . GLN A 1 37  ? -39.017 -10.05  -8.265  1 45.06   ? 37  GLN A HB2  1 c 
ATOM   557  H HB3  . GLN A 1 37  ? -38.424 -8.724  -8.881  1 45.036  ? 37  GLN A HB3  1 c 
ATOM   558  H HG2  . GLN A 1 37  ? -36.631 -8.812  -7.309  1 46.103  ? 37  GLN A HG2  1 c 
ATOM   559  H HG3  . GLN A 1 37  ? -37.214 -10.176 -6.751  1 46.137  ? 37  GLN A HG3  1 c 
ATOM   560  H HE21 . GLN A 1 37  ? -34.624 -9.995  -9.422  1 42.763  ? 37  GLN A HE21 1 c 
ATOM   561  H HE22 . GLN A 1 37  ? -34.555 -10.068 -7.89   1 42.795  ? 37  GLN A HE22 1 c 
ATOM   562  N N    . LEU A 1 38  ? -38.481 -7.155  -5.184  1 48.493  ? 38  LEU A N    1 ? 
ATOM   563  C CA   . LEU A 1 38  ? -37.942 -6.002  -4.48   1 48.152  ? 38  LEU A CA   1 ? 
ATOM   564  C C    . LEU A 1 38  ? -36.447 -6.202  -4.242  1 47.064  ? 38  LEU A C    1 ? 
ATOM   565  O O    . LEU A 1 38  ? -36.035 -6.847  -3.289  1 42.293  ? 38  LEU A O    1 ? 
ATOM   566  C CB   . LEU A 1 38  ? -38.746 -5.857  -3.189  1 57.187  ? 38  LEU A CB   1 ? 
ATOM   567  C CG   . LEU A 1 38  ? -39.157 -4.435  -2.802  1 73.264  ? 38  LEU A CG   1 ? 
ATOM   568  C CD1  . LEU A 1 38  ? -39.851 -3.696  -3.958  1 70.711  ? 38  LEU A CD1  1 ? 
ATOM   569  C CD2  . LEU A 1 38  ? -40.069 -4.518  -1.584  1 76.241  ? 38  LEU A CD2  1 ? 
ATOM   570  H H    . LEU A 1 38  ? -38.665 -7.911  -4.703  1 47.297  ? 38  LEU A H    1 c 
ATOM   571  H HA   . LEU A 1 38  ? -38.069 -5.197  -5.038  1 49.774  ? 38  LEU A HA   1 c 
ATOM   572  H HB2  . LEU A 1 38  ? -39.565 -6.398  -3.272  1 58.099  ? 38  LEU A HB2  1 c 
ATOM   573  H HB3  . LEU A 1 38  ? -38.226 -6.241  -2.446  1 58.004  ? 38  LEU A HB3  1 c 
ATOM   574  H HG   . LEU A 1 38  ? -38.341 -3.931  -2.551  1 69.87   ? 38  LEU A HG   1 c 
ATOM   575  H HD11 . LEU A 1 38  ? -39.19  -3.207  -4.476  1 71.215  ? 38  LEU A HD11 1 c 
ATOM   576  H HD12 . LEU A 1 38  ? -40.505 -3.072  -3.6    1 71.377  ? 38  LEU A HD12 1 c 
ATOM   577  H HD13 . LEU A 1 38  ? -40.301 -4.338  -4.533  1 71.181  ? 38  LEU A HD13 1 c 
ATOM   578  H HD21 . LEU A 1 38  ? -39.624 -5.016  -0.878  1 75.352  ? 38  LEU A HD21 1 c 
ATOM   579  H HD22 . LEU A 1 38  ? -40.895 -4.969  -1.827  1 75.352  ? 38  LEU A HD22 1 c 
ATOM   580  H HD23 . LEU A 1 38  ? -40.272 -3.621  -1.268  1 75.352  ? 38  LEU A HD23 1 c 
ATOM   581  N N    . HIS A 1 39  ? -35.631 -5.675  -5.149  1 47.738  ? 39  HIS A N    1 ? 
ATOM   582  C CA   . HIS A 1 39  ? -34.191 -5.727  -5.001  1 46.853  ? 39  HIS A CA   1 ? 
ATOM   583  C C    . HIS A 1 39  ? -33.752 -4.61   -4.055  1 50.534  ? 39  HIS A C    1 ? 
ATOM   584  O O    . HIS A 1 39  ? -33.382 -3.514  -4.488  1 56.31   ? 39  HIS A O    1 ? 
ATOM   585  C CB   . HIS A 1 39  ? -33.558 -5.653  -6.386  1 43.813  ? 39  HIS A CB   1 ? 
ATOM   586  C CG   . HIS A 1 39  ? -32.085 -5.787  -6.449  1 44.3    ? 39  HIS A CG   1 ? 
ATOM   587  N ND1  . HIS A 1 39  ? -31.469 -7.002  -6.672  1 47.153  ? 39  HIS A ND1  1 ? 
ATOM   588  C CD2  . HIS A 1 39  ? -31.114 -4.876  -6.393  1 47.28   ? 39  HIS A CD2  1 ? 
ATOM   589  C CE1  . HIS A 1 39  ? -30.162 -6.822  -6.726  1 53.587  ? 39  HIS A CE1  1 ? 
ATOM   590  N NE2  . HIS A 1 39  ? -29.92  -5.532  -6.562  1 51.536  ? 39  HIS A NE2  1 ? 
ATOM   591  H H    . HIS A 1 39  ? -35.982 -5.269  -5.889  1 47.355  ? 39  HIS A H    1 c 
ATOM   592  H HA   . HIS A 1 39  ? -33.933 -6.591  -4.6    1 47.155  ? 39  HIS A HA   1 c 
ATOM   593  H HB2  . HIS A 1 39  ? -33.958 -6.355  -6.944  1 44.663  ? 39  HIS A HB2  1 c 
ATOM   594  H HB3  . HIS A 1 39  ? -33.813 -4.802  -6.797  1 44.686  ? 39  HIS A HB3  1 c 
ATOM   595  H HD2  . HIS A 1 39  ? -31.218 -3.954  -6.262  1 47.501  ? 39  HIS A HD2  1 c 
ATOM   596  H HE1  . HIS A 1 39  ? -29.516 -7.496  -6.851  1 51.462  ? 39  HIS A HE1  1 c 
ATOM   597  N N    . PHE A 1 40  ? -33.751 -4.918  -2.754  1 55.972  ? 40  PHE A N    1 ? 
ATOM   598  C CA   . PHE A 1 40  ? -33.551 -3.904  -1.728  1 57.649  ? 40  PHE A CA   1 ? 
ATOM   599  C C    . PHE A 1 40  ? -32.16  -3.951  -1.099  1 61.212  ? 40  PHE A C    1 ? 
ATOM   600  O O    . PHE A 1 40  ? -31.894 -3.106  -0.244  1 68.148  ? 40  PHE A O    1 ? 
ATOM   601  C CB   . PHE A 1 40  ? -34.63  -4.048  -0.656  1 53.432  ? 40  PHE A CB   1 ? 
ATOM   602  C CG   . PHE A 1 40  ? -34.629 -5.377  0.077   1 51.208  ? 40  PHE A CG   1 ? 
ATOM   603  C CD1  . PHE A 1 40  ? -33.637 -5.683  1.002   1 48.065  ? 40  PHE A CD1  1 ? 
ATOM   604  C CD2  . PHE A 1 40  ? -35.629 -6.31   -0.157  1 50.654  ? 40  PHE A CD2  1 ? 
ATOM   605  C CE1  . PHE A 1 40  ? -33.654 -6.89   1.675   1 45.771  ? 40  PHE A CE1  1 ? 
ATOM   606  C CE2  . PHE A 1 40  ? -35.63  -7.525  0.504   1 51.951  ? 40  PHE A CE2  1 ? 
ATOM   607  C CZ   . PHE A 1 40  ? -34.645 -7.811  1.424   1 49.951  ? 40  PHE A CZ   1 ? 
ATOM   608  H H    . PHE A 1 40  ? -33.869 -5.788  -2.498  1 54.84   ? 40  PHE A H    1 c 
ATOM   609  H HA   . PHE A 1 40  ? -33.663 -3.011  -2.146  1 57.041  ? 40  PHE A HA   1 c 
ATOM   610  H HB2  . PHE A 1 40  ? -34.515 -3.325  0.001   1 53.923  ? 40  PHE A HB2  1 c 
ATOM   611  H HB3  . PHE A 1 40  ? -35.507 -3.921  -1.081  1 53.819  ? 40  PHE A HB3  1 c 
ATOM   612  H HD1  . PHE A 1 40  ? -32.959 -5.056  1.189   1 48.455  ? 40  PHE A HD1  1 c 
ATOM   613  H HD2  . PHE A 1 40  ? -36.307 -6.119  -0.786  1 51.002  ? 40  PHE A HD2  1 c 
ATOM   614  H HE1  . PHE A 1 40  ? -32.974 -7.089  2.298   1 47.37   ? 40  PHE A HE1  1 c 
ATOM   615  H HE2  . PHE A 1 40  ? -36.314 -8.151  0.335   1 50.977  ? 40  PHE A HE2  1 c 
ATOM   616  H HZ   . PHE A 1 40  ? -34.649 -8.638  1.879   1 49.439  ? 40  PHE A HZ   1 c 
ATOM   617  N N    . SER A 1 41  ? -31.291 -4.908  -1.49   1 54.096  ? 41  SER A N    1 ? 
ATOM   618  C CA   . SER A 1 41  ? -29.958 -5.017  -0.897  1 54.373  ? 41  SER A CA   1 ? 
ATOM   619  C C    . SER A 1 41  ? -28.877 -5.126  -1.967  1 54.662  ? 41  SER A C    1 ? 
ATOM   620  O O    . SER A 1 41  ? -28.812 -6.112  -2.698  1 60.802  ? 41  SER A O    1 ? 
ATOM   621  C CB   . SER A 1 41  ? -29.846 -6.182  0.035   1 54.315  ? 41  SER A CB   1 ? 
ATOM   622  O OG   . SER A 1 41  ? -28.543 -6.19   0.606   1 57.206  ? 41  SER A OG   1 ? 
ATOM   623  H H    . SER A 1 41  ? -31.53  -5.504  -2.139  1 55.774  ? 41  SER A H    1 c 
ATOM   624  H HA   . SER A 1 41  ? -29.786 -4.196  -0.373  1 54.434  ? 41  SER A HA   1 c 
ATOM   625  H HB2  . SER A 1 41  ? -30.516 -6.104  0.741   1 55.006  ? 41  SER A HB2  1 c 
ATOM   626  H HB3  . SER A 1 41  ? -29.999 -7.011  -0.454  1 55.023  ? 41  SER A HB3  1 c 
ATOM   627  N N    . ASP A 1 42  ? -27.993 -4.132  -1.994  1 50.044  ? 42  ASP A N    1 ? 
ATOM   628  C CA   . ASP A 1 42  ? -26.897 -4.088  -2.94   1 57.437  ? 42  ASP A CA   1 ? 
ATOM   629  C C    . ASP A 1 42  ? -25.759 -3.29   -2.317  1 56.461  ? 42  ASP A C    1 ? 
ATOM   630  O O    . ASP A 1 42  ? -25.793 -2.97   -1.129  1 61.829  ? 42  ASP A O    1 ? 
ATOM   631  C CB   . ASP A 1 42  ? -27.358 -3.561  -4.289  1 59.199  ? 42  ASP A CB   1 ? 
ATOM   632  C CG   . ASP A 1 42  ? -26.607 -4.123  -5.486  1 56.433  ? 42  ASP A CG   1 ? 
ATOM   633  O OD1  . ASP A 1 42  ? -25.393 -3.85   -5.59   1 53.989  ? 42  ASP A OD1  1 ? 
ATOM   634  O OD2  . ASP A 1 42  ? -27.242 -4.842  -6.29   1 55.845  ? 42  ASP A OD2  1 ? 
ATOM   635  H H    . ASP A 1 42  ? -28.08  -3.443  -1.399  1 52.782  ? 42  ASP A H    1 c 
ATOM   636  H HA   . ASP A 1 42  ? -26.582 -5      -3.089  1 56.111  ? 42  ASP A HA   1 c 
ATOM   637  H HB2  . ASP A 1 42  ? -28.312 -3.754  -4.407  1 58.059  ? 42  ASP A HB2  1 c 
ATOM   638  H HB3  . ASP A 1 42  ? -27.247 -2.588  -4.303  1 58.085  ? 42  ASP A HB3  1 c 
ATOM   639  N N    . ASN A 1 43  ? -24.742 -2.994  -3.126  1 55.19   ? 43  ASN A N    1 ? 
ATOM   640  C CA   . ASN A 1 43  ? -23.545 -2.35   -2.627  1 59.35   ? 43  ASN A CA   1 ? 
ATOM   641  C C    . ASN A 1 43  ? -23.855 -0.965  -2.053  1 68.779  ? 43  ASN A C    1 ? 
ATOM   642  O O    . ASN A 1 43  ? -23.222 -0.582  -1.073  1 65.174  ? 43  ASN A O    1 ? 
ATOM   643  C CB   . ASN A 1 43  ? -22.456 -2.271  -3.695  1 58.9    ? 43  ASN A CB   1 ? 
ATOM   644  C CG   . ASN A 1 43  ? -21.858 -3.627  -4.007  1 57.82   ? 43  ASN A CG   1 ? 
ATOM   645  O OD1  . ASN A 1 43  ? -21.631 -4.428  -3.093  1 60.039  ? 43  ASN A OD1  1 ? 
ATOM   646  N ND2  . ASN A 1 43  ? -21.651 -3.922  -5.282  1 53.595  ? 43  ASN A ND2  1 ? 
ATOM   647  H H    . ASN A 1 43  ? -24.779 -3.213  -4.011  1 56.454  ? 43  ASN A H    1 c 
ATOM   648  H HA   . ASN A 1 43  ? -23.197 -2.902  -1.894  1 60.173  ? 43  ASN A HA   1 c 
ATOM   649  H HB2  . ASN A 1 43  ? -22.837 -1.892  -4.512  1 58.703  ? 43  ASN A HB2  1 c 
ATOM   650  H HB3  . ASN A 1 43  ? -21.746 -1.673  -3.387  1 58.791  ? 43  ASN A HB3  1 c 
ATOM   651  H HD21 . ASN A 1 43  ? -21.583 -4.769  -5.535  1 54.912  ? 43  ASN A HD21 1 c 
ATOM   652  H HD22 . ASN A 1 43  ? -21.573 -3.275  -5.884  1 54.928  ? 43  ASN A HD22 1 c 
ATOM   653  N N    . GLU A 1 44  ? -24.807 -0.227  -2.653  1 58.981  ? 44  GLU A N    1 ? 
ATOM   654  C CA   . GLU A 1 44  ? -24.935 1.197   -2.389  1 59.958  ? 44  GLU A CA   1 ? 
ATOM   655  C C    . GLU A 1 44  ? -25.704 1.425   -1.087  1 60.752  ? 44  GLU A C    1 ? 
ATOM   656  O O    . GLU A 1 44  ? -25.507 2.463   -0.452  1 59.474  ? 44  GLU A O    1 ? 
ATOM   657  C CB   . GLU A 1 44  ? -25.56  1.969   -3.557  1 59.606  ? 44  GLU A CB   1 ? 
ATOM   658  C CG   . GLU A 1 44  ? -24.657 2.112   -4.781  1 57.227  ? 44  GLU A CG   1 ? 
ATOM   659  C CD   . GLU A 1 44  ? -24.468 0.838   -5.601  1 64.072  ? 44  GLU A CD   1 ? 
ATOM   660  O OE1  . GLU A 1 44  ? -24.971 -0.249  -5.218  1 60.35   ? 44  GLU A OE1  1 ? 
ATOM   661  O OE2  . GLU A 1 44  ? -23.813 0.945   -6.656  1 64.63   ? 44  GLU A OE2  1 ? 
ATOM   662  H H    . GLU A 1 44  ? -25.385 -0.617  -3.243  1 61.35   ? 44  GLU A H    1 c 
ATOM   663  H HA   . GLU A 1 44  ? -24.022 1.566   -2.267  1 59.915  ? 44  GLU A HA   1 c 
ATOM   664  H HB2  . GLU A 1 44  ? -26.388 1.518   -3.823  1 59.143  ? 44  GLU A HB2  1 c 
ATOM   665  H HB3  . GLU A 1 44  ? -25.799 2.867   -3.246  1 59.143  ? 44  GLU A HB3  1 c 
ATOM   666  H HG2  . GLU A 1 44  ? -25.03  2.803   -5.369  1 59.272  ? 44  GLU A HG2  1 c 
ATOM   667  H HG3  . GLU A 1 44  ? -23.775 2.423   -4.488  1 59.275  ? 44  GLU A HG3  1 c 
ATOM   668  N N    . ASN A 1 45  ? -26.55  0.462   -0.679  1 64.152  ? 45  ASN A N    1 ? 
ATOM   669  C CA   . ASN A 1 45  ? -27.456 0.669   0.447   1 64.183  ? 45  ASN A CA   1 ? 
ATOM   670  C C    . ASN A 1 45  ? -28.261 -0.601  0.734   1 63.368  ? 45  ASN A C    1 ? 
ATOM   671  O O    . ASN A 1 45  ? -28.491 -1.393  -0.179  1 63.873  ? 45  ASN A O    1 ? 
ATOM   672  C CB   . ASN A 1 45  ? -28.391 1.847   0.163   1 69.209  ? 45  ASN A CB   1 ? 
ATOM   673  C CG   . ASN A 1 45  ? -29.346 2.132   1.295   1 69.752  ? 45  ASN A CG   1 ? 
ATOM   674  O OD1  . ASN A 1 45  ? -28.948 2.144   2.466   1 74.251  ? 45  ASN A OD1  1 ? 
ATOM   675  N ND2  . ASN A 1 45  ? -30.611 2.346   0.972   1 69.78   ? 45  ASN A ND2  1 ? 
ATOM   676  H H    . ASN A 1 45  ? -26.571 -0.341  -1.115  1 63.3    ? 45  ASN A H    1 c 
ATOM   677  H HA   . ASN A 1 45  ? -26.918 0.895   1.239   1 64.889  ? 45  ASN A HA   1 c 
ATOM   678  H HB2  . ASN A 1 45  ? -27.863 2.651   -0.003  1 68.074  ? 45  ASN A HB2  1 c 
ATOM   679  H HB3  . ASN A 1 45  ? -28.902 1.654   -0.648  1 68.162  ? 45  ASN A HB3  1 c 
ATOM   680  H HD21 . ASN A 1 45  ? -31.225 2.376   1.61    1 69.672  ? 45  ASN A HD21 1 c 
ATOM   681  H HD22 . ASN A 1 45  ? -30.85  2.47    0.126   1 69.731  ? 45  ASN A HD22 1 c 
ATOM   682  N N    . TYR A 1 46  ? -28.672 -0.78   2.004   1 56.194  ? 46  TYR A N    1 ? 
ATOM   683  C CA   . TYR A 1 46  ? -29.682 -1.751  2.41    1 55.405  ? 46  TYR A CA   1 ? 
ATOM   684  C C    . TYR A 1 46  ? -30.967 -0.978  2.694   1 58.821  ? 46  TYR A C    1 ? 
ATOM   685  O O    . TYR A 1 46  ? -31.03  -0.25   3.679   1 63.716  ? 46  TYR A O    1 ? 
ATOM   686  C CB   . TYR A 1 46  ? -29.245 -2.553  3.645   1 50.113  ? 46  TYR A CB   1 ? 
ATOM   687  C CG   . TYR A 1 46  ? -30.142 -3.734  4.004   1 50.102  ? 46  TYR A CG   1 ? 
ATOM   688  C CD1  . TYR A 1 46  ? -31.283 -3.564  4.784   1 51.32   ? 46  TYR A CD1  1 ? 
ATOM   689  C CD2  . TYR A 1 46  ? -29.882 -5.022  3.533   1 44.203  ? 46  TYR A CD2  1 ? 
ATOM   690  C CE1  . TYR A 1 46  ? -32.094 -4.636  5.133   1 48.639  ? 46  TYR A CE1  1 ? 
ATOM   691  C CE2  . TYR A 1 46  ? -30.692 -6.1    3.873   1 43.856  ? 46  TYR A CE2  1 ? 
ATOM   692  C CZ   . TYR A 1 46  ? -31.814 -5.91   4.662   1 47.952  ? 46  TYR A CZ   1 ? 
ATOM   693  O OH   . TYR A 1 46  ? -32.63  -6.972  4.975   1 51.511  ? 46  TYR A OH   1 ? 
ATOM   694  H H    . TYR A 1 46  ? -28.295 -0.262  2.656   1 57.792  ? 46  TYR A H    1 c 
ATOM   695  H HA   . TYR A 1 46  ? -29.843 -2.385  1.663   1 55.306  ? 46  TYR A HA   1 c 
ATOM   696  H HB2  . TYR A 1 46  ? -28.335 -2.887  3.488   1 51.285  ? 46  TYR A HB2  1 c 
ATOM   697  H HB3  . TYR A 1 46  ? -29.204 -1.943  4.415   1 51.362  ? 46  TYR A HB3  1 c 
ATOM   698  H HD1  . TYR A 1 46  ? -31.483 -2.708  5.122   1 50.533  ? 46  TYR A HD1  1 c 
ATOM   699  H HD2  . TYR A 1 46  ? -29.12  -5.171  2.997   1 45.718  ? 46  TYR A HD2  1 c 
ATOM   700  H HE1  . TYR A 1 46  ? -32.851 -4.495  5.672   1 49.129  ? 46  TYR A HE1  1 c 
ATOM   701  H HE2  . TYR A 1 46  ? -30.493 -6.959  3.543   1 44.989  ? 46  TYR A HE2  1 c 
ATOM   702  N N    . ALA A 1 47  ? -31.988 -1.136  1.837   1 62.585  ? 47  ALA A N    1 ? 
ATOM   703  C CA   . ALA A 1 47  ? -33.056 -0.145  1.707   1 54.884  ? 47  ALA A CA   1 ? 
ATOM   704  C C    . ALA A 1 47  ? -34.366 -0.569  2.372   1 52.252  ? 47  ALA A C    1 ? 
ATOM   705  O O    . ALA A 1 47  ? -35.407 0.004   2.057   1 53.702  ? 47  ALA A O    1 ? 
ATOM   706  C CB   . ALA A 1 47  ? -33.274 0.15    0.235   1 55.2    ? 47  ALA A CB   1 ? 
ATOM   707  H H    . ALA A 1 47  ? -32.026 -1.889  1.32    1 59.803  ? 47  ALA A H    1 c 
ATOM   708  H HA   . ALA A 1 47  ? -32.755 0.694   2.15    1 55.987  ? 47  ALA A HA   1 c 
ATOM   709  H HB1  . ALA A 1 47  ? -32.415 0.242   -0.211  1 55.101  ? 47  ALA A HB1  1 c 
ATOM   710  H HB2  . ALA A 1 47  ? -33.772 -0.577  -0.175  1 55.088  ? 47  ALA A HB2  1 c 
ATOM   711  H HB3  . ALA A 1 47  ? -33.776 0.977   0.138   1 55.095  ? 47  ALA A HB3  1 c 
ATOM   712  N N    . ILE A 1 48  ? -34.333 -1.556  3.278   1 54.839  ? 48  ILE A N    1 ? 
ATOM   713  C CA   . ILE A 1 48  ? -35.452 -1.812  4.171   1 56.325  ? 48  ILE A CA   1 ? 
ATOM   714  C C    . ILE A 1 48  ? -34.961 -1.83   5.622   1 68.218  ? 48  ILE A C    1 ? 
ATOM   715  O O    . ILE A 1 48  ? -33.764 -1.735  5.903   1 68.146  ? 48  ILE A O    1 ? 
ATOM   716  C CB   . ILE A 1 48  ? -36.212 -3.103  3.804   1 57.535  ? 48  ILE A CB   1 ? 
ATOM   717  C CG1  . ILE A 1 48  ? -35.346 -4.357  3.973   1 57.751  ? 48  ILE A CG1  1 ? 
ATOM   718  C CG2  . ILE A 1 48  ? -36.832 -3.018  2.405   1 62.196  ? 48  ILE A CG2  1 ? 
ATOM   719  C CD1  . ILE A 1 48  ? -36.145 -5.615  4.297   1 54.277  ? 48  ILE A CD1  1 ? 
ATOM   720  H H    . ILE A 1 48  ? -33.596 -2.092  3.339   1 54.619  ? 48  ILE A H    1 c 
ATOM   721  H HA   . ILE A 1 48  ? -36.082 -1.071  4.089   1 58.227  ? 48  ILE A HA   1 c 
ATOM   722  H HB   . ILE A 1 48  ? -36.954 -3.188  4.432   1 58.333  ? 48  ILE A HB   1 c 
ATOM   723  H HG12 . ILE A 1 48  ? -34.84  -4.505  3.15    1 56.859  ? 48  ILE A HG12 1 c 
ATOM   724  H HG13 . ILE A 1 48  ? -34.707 -4.205  4.693   1 56.824  ? 48  ILE A HG13 1 c 
ATOM   725  H HG21 . ILE A 1 48  ? -37.362 -3.815  2.234   1 60.778  ? 48  ILE A HG21 1 c 
ATOM   726  H HG22 . ILE A 1 48  ? -36.127 -2.951  1.739   1 60.73   ? 48  ILE A HG22 1 c 
ATOM   727  H HG23 . ILE A 1 48  ? -37.403 -2.233  2.348   1 60.778  ? 48  ILE A HG23 1 c 
ATOM   728  H HD11 . ILE A 1 48  ? -36.637 -5.485  5.13    1 55.348  ? 48  ILE A HD11 1 c 
ATOM   729  H HD12 . ILE A 1 48  ? -35.537 -6.373  4.396   1 55.292  ? 48  ILE A HD12 1 c 
ATOM   730  H HD13 . ILE A 1 48  ? -36.774 -5.798  3.574   1 55.292  ? 48  ILE A HD13 1 c 
ATOM   731  N N    . ALA A 1 49  ? -35.93  -1.95   6.539   1 73.595  ? 49  ALA A N    1 ? 
ATOM   732  C CA   . ALA A 1 49  ? -35.699 -1.902  7.97    1 70.419  ? 49  ALA A CA   1 ? 
ATOM   733  C C    . ALA A 1 49  ? -35.227 -3.26   8.477   1 68.051  ? 49  ALA A C    1 ? 
ATOM   734  O O    . ALA A 1 49  ? -35.772 -4.3    8.089   1 66.952  ? 49  ALA A O    1 ? 
ATOM   735  C CB   . ALA A 1 49  ? -36.965 -1.483  8.69    1 66.877  ? 49  ALA A CB   1 ? 
ATOM   736  H H    . ALA A 1 49  ? -36.792 -2.042  6.252   1 71.158  ? 49  ALA A H    1 c 
ATOM   737  H HA   . ALA A 1 49  ? -34.986 -1.228  8.149   1 69.794  ? 49  ALA A HA   1 c 
ATOM   738  H HB1  . ALA A 1 49  ? -37.187 -0.567  8.454   1 67.892  ? 49  ALA A HB1  1 c 
ATOM   739  H HB2  . ALA A 1 49  ? -37.697 -2.068  8.432   1 67.923  ? 49  ALA A HB2  1 c 
ATOM   740  H HB3  . ALA A 1 49  ? -36.83  -1.542  9.65    1 67.908  ? 49  ALA A HB3  1 c 
ATOM   741  N N    . SER A 1 50  ? -34.265 -3.191  9.41    1 60.631  ? 50  SER A N    1 ? 
ATOM   742  C CA   . SER A 1 50  ? -33.619 -4.35   9.999   1 64.07   ? 50  SER A CA   1 ? 
ATOM   743  C C    . SER A 1 50  ? -33.287 -4.075  11.47   1 62.749  ? 50  SER A C    1 ? 
ATOM   744  O O    . SER A 1 50  ? -32.423 -3.245  11.773  1 57.692  ? 50  SER A O    1 ? 
ATOM   745  C CB   . SER A 1 50  ? -32.378 -4.702  9.205   1 62.746  ? 50  SER A CB   1 ? 
ATOM   746  O OG   . SER A 1 50  ? -31.765 -5.897  9.668   1 61.233  ? 50  SER A OG   1 ? 
ATOM   747  H H    . SER A 1 50  ? -34     -2.366  9.699   1 63.211  ? 50  SER A H    1 c 
ATOM   748  H HA   . SER A 1 50  ? -34.245 -5.11   9.957   1 63.047  ? 50  SER A HA   1 c 
ATOM   749  H HB2  . SER A 1 50  ? -32.62  -4.809  8.265   1 62.688  ? 50  SER A HB2  1 c 
ATOM   750  H HB3  . SER A 1 50  ? -31.742 -3.967  9.267   1 62.734  ? 50  SER A HB3  1 c 
ATOM   751  N N    . GLU A 1 51  ? -34.01  -4.749  12.379  1 67.921  ? 51  GLU A N    1 ? 
ATOM   752  C CA   . GLU A 1 51  ? -33.582 -4.871  13.765  1 72.547  ? 51  GLU A CA   1 ? 
ATOM   753  C C    . GLU A 1 51  ? -32.117 -5.298  13.741  1 73.747  ? 51  GLU A C    1 ? 
ATOM   754  O O    . GLU A 1 51  ? -31.241 -4.508  14.094  1 72.238  ? 51  GLU A O    1 ? 
ATOM   755  C CB   . GLU A 1 51  ? -34.396 -5.892  14.574  1 80.173  ? 51  GLU A CB   1 ? 
ATOM   756  C CG   . GLU A 1 51  ? -35.633 -5.335  15.279  1 85.155  ? 51  GLU A CG   1 ? 
ATOM   757  C CD   . GLU A 1 51  ? -35.998 -6.055  16.573  1 87.075  ? 51  GLU A CD   1 ? 
ATOM   758  O OE1  . GLU A 1 51  ? -37.166 -6.484  16.773  1 81.967  ? 51  GLU A OE1  1 ? 
ATOM   759  O OE2  . GLU A 1 51  ? -35.071 -6.159  17.41   1 68.09   ? 51  GLU A OE2  1 ? 
ATOM   760  H H    . GLU A 1 51  ? -34.8   -5.134  12.129  1 67.74   ? 51  GLU A H    1 c 
ATOM   761  H HA   . GLU A 1 51  ? -33.647 -3.979  14.192  1 73.202  ? 51  GLU A HA   1 c 
ATOM   762  H HB2  . GLU A 1 51  ? -34.691 -6.603  13.967  1 79.369  ? 51  GLU A HB2  1 c 
ATOM   763  H HB3  . GLU A 1 51  ? -33.806 -6.302  15.24   1 79.373  ? 51  GLU A HB3  1 c 
ATOM   764  H HG2  . GLU A 1 51  ? -35.48  -4.395  15.492  1 84.241  ? 51  GLU A HG2  1 c 
ATOM   765  H HG3  . GLU A 1 51  ? -36.4   -5.382  14.668  1 84.394  ? 51  GLU A HG3  1 c 
ATOM   766  N N    . TYR A 1 52  ? -31.879 -6.495  13.176  1 69.861  ? 52  TYR A N    1 ? 
ATOM   767  C CA   . TYR A 1 52  ? -30.592 -7.168  13.229  1 70.038  ? 52  TYR A CA   1 ? 
ATOM   768  C C    . TYR A 1 52  ? -29.452 -6.271  12.739  1 70.082  ? 52  TYR A C    1 ? 
ATOM   769  O O    . TYR A 1 52  ? -28.356 -6.369  13.281  1 72.98   ? 52  TYR A O    1 ? 
ATOM   770  C CB   . TYR A 1 52  ? -30.658 -8.488  12.454  1 77.768  ? 52  TYR A CB   1 ? 
ATOM   771  C CG   . TYR A 1 52  ? -29.359 -9.28   12.524  1 83.002  ? 52  TYR A CG   1 ? 
ATOM   772  C CD1  . TYR A 1 52  ? -28.96  -9.909  13.703  1 83.22   ? 52  TYR A CD1  1 ? 
ATOM   773  C CD2  . TYR A 1 52  ? -28.518 -9.378  11.421  1 85.899  ? 52  TYR A CD2  1 ? 
ATOM   774  C CE1  . TYR A 1 52  ? -27.765 -10.612 13.779  1 82.739  ? 52  TYR A CE1  1 ? 
ATOM   775  C CE2  . TYR A 1 52  ? -27.326 -10.088 11.48   1 86.585  ? 52  TYR A CE2  1 ? 
ATOM   776  C CZ   . TYR A 1 52  ? -26.95  -10.708 12.661  1 88.614  ? 52  TYR A CZ   1 ? 
ATOM   777  O OH   . TYR A 1 52  ? -25.775 -11.404 12.708  1 80.589  ? 52  TYR A OH   1 ? 
ATOM   778  H H    . TYR A 1 52  ? -32.561 -6.911  12.733  1 70.881  ? 52  TYR A H    1 c 
ATOM   779  H HA   . TYR A 1 52  ? -30.411 -7.388  14.181  1 71.378  ? 52  TYR A HA   1 c 
ATOM   780  H HB2  . TYR A 1 52  ? -31.388 -9.033  12.823  1 77.095  ? 52  TYR A HB2  1 c 
ATOM   781  H HB3  . TYR A 1 52  ? -30.865 -8.291  11.513  1 77.172  ? 52  TYR A HB3  1 c 
ATOM   782  H HD1  . TYR A 1 52  ? -29.508 -9.848  14.469  1 83.086  ? 52  TYR A HD1  1 c 
ATOM   783  H HD2  . TYR A 1 52  ? -28.765 -8.96   10.611  1 85.254  ? 52  TYR A HD2  1 c 
ATOM   784  H HE1  . TYR A 1 52  ? -27.516 -11.037 14.582  1 84.24   ? 52  TYR A HE1  1 c 
ATOM   785  H HE2  . TYR A 1 52  ? -26.773 -10.148 10.72   1 86.757  ? 52  TYR A HE2  1 c 
ATOM   786  N N    . LEU A 1 53  ? -29.689 -5.402  11.74   1 71.121  ? 53  LEU A N    1 ? 
ATOM   787  C CA   . LEU A 1 53  ? -28.631 -4.547  11.21   1 69.221  ? 53  LEU A CA   1 ? 
ATOM   788  C C    . LEU A 1 53  ? -28.684 -3.14   11.804  1 71.221  ? 53  LEU A C    1 ? 
ATOM   789  O O    . LEU A 1 53  ? -27.79  -2.342  11.522  1 68.845  ? 53  LEU A O    1 ? 
ATOM   790  C CB   . LEU A 1 53  ? -28.671 -4.458  9.684   1 75.624  ? 53  LEU A CB   1 ? 
ATOM   791  C CG   . LEU A 1 53  ? -28.541 -5.772  8.907   1 80.5    ? 53  LEU A CG   1 ? 
ATOM   792  C CD1  . LEU A 1 53  ? -28.983 -5.579  7.467   1 74.574  ? 53  LEU A CD1  1 ? 
ATOM   793  C CD2  . LEU A 1 53  ? -27.114 -6.294  8.952   1 83.545  ? 53  LEU A CD2  1 ? 
ATOM   794  H H    . LEU A 1 53  ? -30.521 -5.356  11.363  1 70.48   ? 53  LEU A H    1 c 
ATOM   795  H HA   . LEU A 1 53  ? -27.76  -4.941  11.469  1 71.17   ? 53  LEU A HA   1 c 
ATOM   796  H HB2  . LEU A 1 53  ? -29.515 -4.024  9.424   1 75.052  ? 53  LEU A HB2  1 c 
ATOM   797  H HB3  . LEU A 1 53  ? -27.94  -3.866  9.398   1 75.079  ? 53  LEU A HB3  1 c 
ATOM   798  H HG   . LEU A 1 53  ? -29.134 -6.447  9.327   1 78.857  ? 53  LEU A HG   1 c 
ATOM   799  H HD11 . LEU A 1 53  ? -29.947 -5.46   7.436   1 76.27   ? 53  LEU A HD11 1 c 
ATOM   800  H HD12 . LEU A 1 53  ? -28.736 -6.36   6.944   1 76.242  ? 53  LEU A HD12 1 c 
ATOM   801  H HD13 . LEU A 1 53  ? -28.548 -4.792  7.097   1 76.27   ? 53  LEU A HD13 1 c 
ATOM   802  H HD21 . LEU A 1 53  ? -26.828 -6.376  9.876   1 82.405  ? 53  LEU A HD21 1 c 
ATOM   803  H HD22 . LEU A 1 53  ? -26.527 -5.676  8.485   1 82.58   ? 53  LEU A HD22 1 c 
ATOM   804  H HD23 . LEU A 1 53  ? -27.072 -7.165  8.522   1 82.58   ? 53  LEU A HD23 1 c 
ATOM   805  N N    . GLY A 1 54  ? -29.731 -2.808  12.575  1 74.121  ? 54  GLY A N    1 ? 
ATOM   806  C CA   . GLY A 1 54  ? -29.83  -1.501  13.217  1 75.678  ? 54  GLY A CA   1 ? 
ATOM   807  C C    . GLY A 1 54  ? -30.388 -0.422  12.283  1 75.133  ? 54  GLY A C    1 ? 
ATOM   808  O O    . GLY A 1 54  ? -29.908 0.714   12.266  1 63.158  ? 54  GLY A O    1 ? 
ATOM   809  H H    . GLY A 1 54  ? -30.413 -3.402  12.696  1 73.688  ? 54  GLY A H    1 c 
ATOM   810  H HA2  . GLY A 1 54  ? -30.417 -1.58   14.005  1 75.172  ? 54  GLY A HA2  1 c 
ATOM   811  H HA3  . GLY A 1 54  ? -28.938 -1.228  13.536  1 75.126  ? 54  GLY A HA3  1 c 
ATOM   812  N N    . GLN A 1 55  ? -31.412 -0.786  11.502  1 72.351  ? 55  GLN A N    1 ? 
ATOM   813  C CA   . GLN A 1 55  ? -32.268 0.19    10.845  1 77.449  ? 55  GLN A CA   1 ? 
ATOM   814  C C    . GLN A 1 55  ? -33.661 0.012   11.444  1 76.322  ? 55  GLN A C    1 ? 
ATOM   815  O O    . GLN A 1 55  ? -34.369 -0.927  11.096  1 74.062  ? 55  GLN A O    1 ? 
ATOM   816  C CB   . GLN A 1 55  ? -32.131 0.059   9.326   1 70.097  ? 55  GLN A CB   1 ? 
ATOM   817  C CG   . GLN A 1 55  ? -30.82  0.642   8.802   1 65.696  ? 55  GLN A CG   1 ? 
ATOM   818  C CD   . GLN A 1 55  ? -30.628 0.509   7.308   1 65.824  ? 55  GLN A CD   1 ? 
ATOM   819  O OE1  . GLN A 1 55  ? -29.784 1.184   6.71    1 56.614  ? 55  GLN A OE1  1 ? 
ATOM   820  N NE2  . GLN A 1 55  ? -31.403 -0.364  6.683   1 71.115  ? 55  GLN A NE2  1 ? 
ATOM   821  H H    . GLN A 1 55  ? -31.587 -1.673  11.374  1 74.085  ? 55  GLN A H    1 c 
ATOM   822  H HA   . GLN A 1 55  ? -31.949 1.097   11.078  1 74.811  ? 55  GLN A HA   1 c 
ATOM   823  H HB2  . GLN A 1 55  ? -32.177 -0.891  9.092   1 70.645  ? 55  GLN A HB2  1 c 
ATOM   824  H HB3  . GLN A 1 55  ? -32.881 0.51    8.892   1 70.6    ? 55  GLN A HB3  1 c 
ATOM   825  H HG2  . GLN A 1 55  ? -30.777 1.593   9.037   1 66.719  ? 55  GLN A HG2  1 c 
ATOM   826  H HG3  . GLN A 1 55  ? -30.071 0.195   9.251   1 66.701  ? 55  GLN A HG3  1 c 
ATOM   827  H HE21 . GLN A 1 55  ? -31.956 -0.092  6.049   1 69.334  ? 55  GLN A HE21 1 c 
ATOM   828  H HE22 . GLN A 1 55  ? -31.361 -1.223  6.899   1 69.254  ? 55  GLN A HE22 1 c 
ATOM   829  N N    . SER A 1 56  ? -33.995 0.88    12.409  1 84.587  ? 56  SER A N    1 ? 
ATOM   830  C CA   . SER A 1 56  ? -35.146 0.684   13.276  1 87.139  ? 56  SER A CA   1 ? 
ATOM   831  C C    . SER A 1 56  ? -36.143 1.837   13.203  1 77.309  ? 56  SER A C    1 ? 
ATOM   832  O O    . SER A 1 56  ? -37.296 1.64    13.591  1 71.512  ? 56  SER A O    1 ? 
ATOM   833  C CB   . SER A 1 56  ? -34.675 0.474   14.675  1 88.388  ? 56  SER A CB   1 ? 
ATOM   834  O OG   . SER A 1 56  ? -33.748 -0.598  14.711  1 89.668  ? 56  SER A OG   1 ? 
ATOM   835  H H    . SER A 1 56  ? -33.452 1.599   12.564  1 82.882  ? 56  SER A H    1 c 
ATOM   836  H HA   . SER A 1 56  ? -35.618 -0.136  12.988  1 84.78   ? 56  SER A HA   1 c 
ATOM   837  H HB2  . SER A 1 56  ? -34.249 1.289   15.002  1 88.401  ? 56  SER A HB2  1 c 
ATOM   838  H HB3  . SER A 1 56  ? -35.437 0.269   15.249  1 88.398  ? 56  SER A HB3  1 c 
ATOM   839  N N    . SER A 1 57  ? -35.706 3.017   12.726  1 76.58   ? 57  SER A N    1 ? 
ATOM   840  C CA   . SER A 1 57  ? -36.556 4.198   12.732  1 79.567  ? 57  SER A CA   1 ? 
ATOM   841  C C    . SER A 1 57  ? -37.929 3.842   12.166  1 83.914  ? 57  SER A C    1 ? 
ATOM   842  O O    . SER A 1 57  ? -38.018 3.263   11.082  1 83.378  ? 57  SER A O    1 ? 
ATOM   843  C CB   . SER A 1 57  ? -35.939 5.354   11.972  1 80.942  ? 57  SER A CB   1 ? 
ATOM   844  O OG   . SER A 1 57  ? -36.838 6.455   11.898  1 78.927  ? 57  SER A OG   1 ? 
ATOM   845  H H    . SER A 1 57  ? -34.862 3.093   12.387  1 77.605  ? 57  SER A H    1 c 
ATOM   846  H HA   . SER A 1 57  ? -36.671 4.479   13.675  1 79.936  ? 57  SER A HA   1 c 
ATOM   847  H HB2  . SER A 1 57  ? -35.118 5.634   12.418  1 80.135  ? 57  SER A HB2  1 c 
ATOM   848  H HB3  . SER A 1 57  ? -35.712 5.062   11.069  1 80.084  ? 57  SER A HB3  1 c 
ATOM   849  N N    . GLU A 1 58  ? -38.983 4.17    12.926  1 74.695  ? 58  GLU A N    1 ? 
ATOM   850  C CA   . GLU A 1 58  ? -40.353 4.013   12.462  1 70.784  ? 58  GLU A CA   1 ? 
ATOM   851  C C    . GLU A 1 58  ? -40.773 5.244   11.652  1 74.013  ? 58  GLU A C    1 ? 
ATOM   852  O O    . GLU A 1 58  ? -41.934 5.321   11.245  1 76.215  ? 58  GLU A O    1 ? 
ATOM   853  C CB   . GLU A 1 58  ? -41.301 3.693   13.623  1 63.169  ? 58  GLU A CB   1 ? 
ATOM   854  H H    . GLU A 1 58  ? -38.841 4.513   13.762  1 75.843  ? 58  GLU A H    1 c 
ATOM   855  H HA   . GLU A 1 58  ? -40.383 3.23    11.855  1 70.735  ? 58  GLU A HA   1 c 
ATOM   856  N N    . ASN A 1 59  ? -39.834 6.17    11.371  1 69.005  ? 59  ASN A N    1 ? 
ATOM   857  C CA   . ASN A 1 59  ? -40.124 7.39    10.631  1 79.518  ? 59  ASN A CA   1 ? 
ATOM   858  C C    . ASN A 1 59  ? -39.524 7.33    9.223   1 78.239  ? 59  ASN A C    1 ? 
ATOM   859  O O    . ASN A 1 59  ? -38.376 6.921   9.046   1 74.984  ? 59  ASN A O    1 ? 
ATOM   860  C CB   . ASN A 1 59  ? -39.599 8.622   11.364  1 85.658  ? 59  ASN A CB   1 ? 
ATOM   861  C CG   . ASN A 1 59  ? -40.142 8.754   12.767  1 89.572  ? 59  ASN A CG   1 ? 
ATOM   862  O OD1  . ASN A 1 59  ? -41.031 8       13.184  1 90.221  ? 59  ASN A OD1  1 ? 
ATOM   863  N ND2  . ASN A 1 59  ? -39.584 9.691   13.516  1 96.596  ? 59  ASN A ND2  1 ? 
ATOM   864  H H    . ASN A 1 59  ? -38.979 6.05    11.666  1 72.548  ? 59  ASN A H    1 c 
ATOM   865  H HA   . ASN A 1 59  ? -41.098 7.489   10.555  1 78.165  ? 59  ASN A HA   1 c 
ATOM   866  H HB2  . ASN A 1 59  ? -38.623 8.576   11.405  1 85.096  ? 59  ASN A HB2  1 c 
ATOM   867  H HB3  . ASN A 1 59  ? -39.84  9.421   10.855  1 85.096  ? 59  ASN A HB3  1 c 
ATOM   868  H HD21 . ASN A 1 59  ? -39.417 9.531   14.373  1 94.363  ? 59  ASN A HD21 1 c 
ATOM   869  H HD22 . ASN A 1 59  ? -39.38  10.477  13.162  1 94.315  ? 59  ASN A HD22 1 c 
ATOM   870  N N    . THR A 1 60  ? -40.301 7.801   8.235   1 73.425  ? 60  THR A N    1 ? 
ATOM   871  C CA   . THR A 1 60  ? -39.889 7.875   6.843   1 74.474  ? 60  THR A CA   1 ? 
ATOM   872  C C    . THR A 1 60  ? -38.573 8.649   6.754   1 83.96   ? 60  THR A C    1 ? 
ATOM   873  O O    . THR A 1 60  ? -38.321 9.532   7.57    1 87.233  ? 60  THR A O    1 ? 
ATOM   874  C CB   . THR A 1 60  ? -41.011 8.533   6.034   1 71.839  ? 60  THR A CB   1 ? 
ATOM   875  O OG1  . THR A 1 60  ? -42.165 7.726   6.246   1 62.248  ? 60  THR A OG1  1 ? 
ATOM   876  C CG2  . THR A 1 60  ? -40.736 8.601   4.541   1 71.948  ? 60  THR A CG2  1 ? 
ATOM   877  H H    . THR A 1 60  ? -41.141 8.094   8.448   1 74.822  ? 60  THR A H    1 c 
ATOM   878  H HA   . THR A 1 60  ? -39.75  6.964   6.511   1 75.423  ? 60  THR A HA   1 c 
ATOM   879  H HB   . THR A 1 60  ? -41.179 9.443   6.377   1 70.323  ? 60  THR A HB   1 c 
ATOM   880  H HG21 . THR A 1 60  ? -41.563 8.792   4.068   1 71.927  ? 60  THR A HG21 1 c 
ATOM   881  H HG22 . THR A 1 60  ? -40.379 7.751   4.237   1 71.924  ? 60  THR A HG22 1 c 
ATOM   882  H HG23 . THR A 1 60  ? -40.091 9.306   4.361   1 71.966  ? 60  THR A HG23 1 c 
ATOM   883  N N    . ASN A 1 61  ? -37.728 8.275   5.785   1 80.404  ? 61  ASN A N    1 ? 
ATOM   884  C CA   . ASN A 1 61  ? -36.35  8.742   5.712   1 77.384  ? 61  ASN A CA   1 ? 
ATOM   885  C C    . ASN A 1 61  ? -35.795 8.439   4.321   1 70.378  ? 61  ASN A C    1 ? 
ATOM   886  O O    . ASN A 1 61  ? -36.395 7.668   3.584   1 64.57   ? 61  ASN A O    1 ? 
ATOM   887  C CB   . ASN A 1 61  ? -35.5   8.085   6.796   1 75.183  ? 61  ASN A CB   1 ? 
ATOM   888  C CG   . ASN A 1 61  ? -35.396 6.589   6.592   1 74.866  ? 61  ASN A CG   1 ? 
ATOM   889  O OD1  . ASN A 1 61  ? -34.544 6.126   5.825   1 63.16   ? 61  ASN A OD1  1 ? 
ATOM   890  N ND2  . ASN A 1 61  ? -36.252 5.82    7.248   1 72.36   ? 61  ASN A ND2  1 ? 
ATOM   891  H H    . ASN A 1 61  ? -38.028 7.702   5.138   1 80.38   ? 61  ASN A H    1 c 
ATOM   892  H HA   . ASN A 1 61  ? -36.335 9.715   5.859   1 76.307  ? 61  ASN A HA   1 c 
ATOM   893  H HB2  . ASN A 1 61  ? -34.604 8.475   6.782   1 75.593  ? 61  ASN A HB2  1 c 
ATOM   894  H HB3  . ASN A 1 61  ? -35.896 8.264   7.672   1 75.635  ? 61  ASN A HB3  1 c 
ATOM   895  H HD21 . ASN A 1 61  ? -36.004 5.012   7.519   1 73.125  ? 61  ASN A HD21 1 c 
ATOM   896  H HD22 . ASN A 1 61  ? -37.072 6.113   7.415   1 73.136  ? 61  ASN A HD22 1 c 
ATOM   897  N N    . ASN A 1 62  ? -34.609 8.966   4.012   1 68.826  ? 62  ASN A N    1 ? 
ATOM   898  C CA   . ASN A 1 62  ? -34.027 8.807   2.687   1 85.644  ? 62  ASN A CA   1 ? 
ATOM   899  C C    . ASN A 1 62  ? -33.194 7.522   2.532   1 81.679  ? 62  ASN A C    1 ? 
ATOM   900  O O    . ASN A 1 62  ? -32.573 7.342   1.487   1 79.231  ? 62  ASN A O    1 ? 
ATOM   901  C CB   . ASN A 1 62  ? -33.234 10.059  2.324   1 89.351  ? 62  ASN A CB   1 ? 
ATOM   902  C CG   . ASN A 1 62  ? -34.138 11.25   2.112   1 95.198  ? 62  ASN A CG   1 ? 
ATOM   903  O OD1  . ASN A 1 62  ? -34.989 11.235  1.216   1 102.041 ? 62  ASN A OD1  1 ? 
ATOM   904  N ND2  . ASN A 1 62  ? -33.975 12.287  2.917   1 102.672 ? 62  ASN A ND2  1 ? 
ATOM   905  H H    . ASN A 1 62  ? -34.147 9.438   4.644   1 72.966  ? 62  ASN A H    1 c 
ATOM   906  H HA   . ASN A 1 62  ? -34.767 8.748   2.041   1 81.989  ? 62  ASN A HA   1 c 
ATOM   907  H HB2  . ASN A 1 62  ? -32.599 10.259  3.041   1 89.729  ? 62  ASN A HB2  1 c 
ATOM   908  H HB3  . ASN A 1 62  ? -32.725 9.897   1.505   1 89.683  ? 62  ASN A HB3  1 c 
ATOM   909  H HD21 . ASN A 1 62  ? -34.681 12.674  3.289   1 100.311 ? 62  ASN A HD21 1 c 
ATOM   910  H HD22 . ASN A 1 62  ? -33.16  12.594  3.085   1 100.308 ? 62  ASN A HD22 1 c 
ATOM   911  N N    . THR A 1 63  ? -33.184 6.615   3.526   1 75.057  ? 63  THR A N    1 ? 
ATOM   912  C CA   . THR A 1 63  ? -32.288 5.465   3.507   1 73.156  ? 63  THR A CA   1 ? 
ATOM   913  C C    . THR A 1 63  ? -33.095 4.18    3.327   1 64.829  ? 63  THR A C    1 ? 
ATOM   914  O O    . THR A 1 63  ? -32.821 3.423   2.409   1 69.544  ? 63  THR A O    1 ? 
ATOM   915  C CB   . THR A 1 63  ? -31.419 5.405   4.766   1 73.137  ? 63  THR A CB   1 ? 
ATOM   916  O OG1  . THR A 1 63  ? -30.703 6.632   4.858   1 69.809  ? 63  THR A OG1  1 ? 
ATOM   917  C CG2  . THR A 1 63  ? -30.375 4.3     4.709   1 70.829  ? 63  THR A CG2  1 ? 
ATOM   918  H H    . THR A 1 63  ? -33.746 6.714   4.238   1 75.934  ? 63  THR A H    1 c 
ATOM   919  H HA   . THR A 1 63  ? -31.686 5.554   2.738   1 71.98   ? 63  THR A HA   1 c 
ATOM   920  H HB   . THR A 1 63  ? -31.986 5.293   5.566   1 71.971  ? 63  THR A HB   1 c 
ATOM   921  H HG21 . THR A 1 63  ? -29.796 4.362   5.488   1 71.485  ? 63  THR A HG21 1 c 
ATOM   922  H HG22 . THR A 1 63  ? -29.842 4.399   3.903   1 71.485  ? 63  THR A HG22 1 c 
ATOM   923  H HG23 . THR A 1 63  ? -30.811 3.432   4.701   1 71.43   ? 63  THR A HG23 1 c 
ATOM   924  N N    . TYR A 1 64  ? -34.067 3.915   4.199   1 62.398  ? 64  TYR A N    1 ? 
ATOM   925  C CA   . TYR A 1 64  ? -34.75  2.633   4.177   1 62.999  ? 64  TYR A CA   1 ? 
ATOM   926  C C    . TYR A 1 64  ? -36.239 2.804   4.397   1 67.955  ? 64  TYR A C    1 ? 
ATOM   927  O O    . TYR A 1 64  ? -36.67  3.731   5.083   1 73.55   ? 64  TYR A O    1 ? 
ATOM   928  C CB   . TYR A 1 64  ? -34.304 1.638   5.25    1 61.786  ? 64  TYR A CB   1 ? 
ATOM   929  C CG   . TYR A 1 64  ? -34.132 2.191   6.656   1 61.505  ? 64  TYR A CG   1 ? 
ATOM   930  C CD1  . TYR A 1 64  ? -33.009 2.95    6.982   1 67.122  ? 64  TYR A CD1  1 ? 
ATOM   931  C CD2  . TYR A 1 64  ? -35.056 1.931   7.666   1 63.629  ? 64  TYR A CD2  1 ? 
ATOM   932  C CE1  . TYR A 1 64  ? -32.816 3.441   8.266   1 71.792  ? 64  TYR A CE1  1 ? 
ATOM   933  C CE2  . TYR A 1 64  ? -34.872 2.41    8.959   1 65.26   ? 64  TYR A CE2  1 ? 
ATOM   934  C CZ   . TYR A 1 64  ? -33.752 3.178   9.258   1 72.732  ? 64  TYR A CZ   1 ? 
ATOM   935  O OH   . TYR A 1 64  ? -33.53  3.666   10.519  1 69.034  ? 64  TYR A OH   1 ? 
ATOM   936  H H    . TYR A 1 64  ? -34.305 4.536   4.825   1 63.404  ? 64  TYR A H    1 c 
ATOM   937  H HA   . TYR A 1 64  ? -34.611 2.214   3.289   1 63.514  ? 64  TYR A HA   1 c 
ATOM   938  H HB2  . TYR A 1 64  ? -34.956 0.905   5.282   1 62.094  ? 64  TYR A HB2  1 c 
ATOM   939  H HB3  . TYR A 1 64  ? -33.45  1.248   4.962   1 62.063  ? 64  TYR A HB3  1 c 
ATOM   940  H HD1  . TYR A 1 64  ? -32.367 3.13    6.319   1 66.909  ? 64  TYR A HD1  1 c 
ATOM   941  H HD2  . TYR A 1 64  ? -35.818 1.409   7.473   1 63.628  ? 64  TYR A HD2  1 c 
ATOM   942  H HE1  . TYR A 1 64  ? -32.051 3.955   8.465   1 70.717  ? 64  TYR A HE1  1 c 
ATOM   943  H HE2  . TYR A 1 64  ? -35.511 2.23    9.627   1 66.524  ? 64  TYR A HE2  1 c 
ATOM   944  N N    . LEU A 1 65  ? -36.981 1.852   3.813   1 65.612  ? 65  LEU A N    1 ? 
ATOM   945  C CA   . LEU A 1 65  ? -38.386 1.658   4.109   1 66.864  ? 65  LEU A CA   1 ? 
ATOM   946  C C    . LEU A 1 65  ? -38.477 1.224   5.564   1 63.703  ? 65  LEU A C    1 ? 
ATOM   947  O O    . LEU A 1 65  ? -37.76  0.322   5.997   1 64.344  ? 65  LEU A O    1 ? 
ATOM   948  C CB   . LEU A 1 65  ? -39.074 0.618   3.222   1 67.076  ? 65  LEU A CB   1 ? 
ATOM   949  C CG   . LEU A 1 65  ? -39.297 0.97    1.75    1 73.331  ? 65  LEU A CG   1 ? 
ATOM   950  C CD1  . LEU A 1 65  ? -40.069 -0.174  1.116   1 73.99   ? 65  LEU A CD1  1 ? 
ATOM   951  C CD2  . LEU A 1 65  ? -40.035 2.281   1.567   1 80.734  ? 65  LEU A CD2  1 ? 
ATOM   952  H H    . LEU A 1 65  ? -36.591 1.3     3.199   1 66.399  ? 65  LEU A H    1 c 
ATOM   953  H HA   . LEU A 1 65  ? -38.843 2.529   4.005   1 66.16   ? 65  LEU A HA   1 c 
ATOM   954  H HB2  . LEU A 1 65  ? -38.543 -0.211  3.261   1 68.404  ? 65  LEU A HB2  1 c 
ATOM   955  H HB3  . LEU A 1 65  ? -39.95  0.41    3.622   1 68.409  ? 65  LEU A HB3  1 c 
ATOM   956  H HG   . LEU A 1 65  ? -38.413 1.04    1.306   1 73.563  ? 65  LEU A HG   1 c 
ATOM   957  H HD11 . LEU A 1 65  ? -39.577 -1.004  1.234   1 73.794  ? 65  LEU A HD11 1 c 
ATOM   958  H HD12 . LEU A 1 65  ? -40.186 -0.001  0.166   1 73.794  ? 65  LEU A HD12 1 c 
ATOM   959  H HD13 . LEU A 1 65  ? -40.941 -0.253  1.539   1 73.791  ? 65  LEU A HD13 1 c 
ATOM   960  H HD21 . LEU A 1 65  ? -39.43  3.022   1.74    1 78.369  ? 65  LEU A HD21 1 c 
ATOM   961  H HD22 . LEU A 1 65  ? -40.782 2.323   2.187   1 78.438  ? 65  LEU A HD22 1 c 
ATOM   962  H HD23 . LEU A 1 65  ? -40.368 2.343   0.656   1 78.418  ? 65  LEU A HD23 1 c 
ATOM   963  N N    . THR A 1 66  ? -39.406 1.846   6.28    1 59.013  ? 66  THR A N    1 ? 
ATOM   964  C CA   . THR A 1 66  ? -39.68  1.479   7.657   1 63.735  ? 66  THR A CA   1 ? 
ATOM   965  C C    . THR A 1 66  ? -40.406 0.147   7.625   1 57.668  ? 66  THR A C    1 ? 
ATOM   966  O O    . THR A 1 66  ? -41.031 -0.194  6.629   1 61.583  ? 66  THR A O    1 ? 
ATOM   967  C CB   . THR A 1 66  ? -40.524 2.553   8.353   1 69.053  ? 66  THR A CB   1 ? 
ATOM   968  O OG1  . THR A 1 66  ? -41.847 2.441   7.831   1 67.793  ? 66  THR A OG1  1 ? 
ATOM   969  C CG2  . THR A 1 66  ? -39.976 3.956   8.14    1 68.356  ? 66  THR A CG2  1 ? 
ATOM   970  H H    . THR A 1 66  ? -39.906 2.506   5.893   1 61.323  ? 66  THR A H    1 c 
ATOM   971  H HA   . THR A 1 66  ? -38.83  1.378   8.138   1 62.561  ? 66  THR A HA   1 c 
ATOM   972  H HB   . THR A 1 66  ? -40.544 2.369   9.322   1 67.687  ? 66  THR A HB   1 c 
ATOM   973  H HG21 . THR A 1 66  ? -39.884 4.399   9       1 68.571  ? 66  THR A HG21 1 c 
ATOM   974  H HG22 . THR A 1 66  ? -40.588 4.465   7.584   1 68.58   ? 66  THR A HG22 1 c 
ATOM   975  H HG23 . THR A 1 66  ? -39.106 3.912   7.709   1 68.482  ? 66  THR A HG23 1 c 
ATOM   976  N N    . LYS A 1 67  ? -40.34  -0.569  8.742   1 62.562  ? 67  LYS A N    1 ? 
ATOM   977  C CA   . LYS A 1 67  ? -40.989 -1.86   8.865   1 66.242  ? 67  LYS A CA   1 ? 
ATOM   978  C C    . LYS A 1 67  ? -42.44  -1.764  8.4     1 68.963  ? 67  LYS A C    1 ? 
ATOM   979  O O    . LYS A 1 67  ? -42.873 -2.559  7.575   1 71.965  ? 67  LYS A O    1 ? 
ATOM   980  C CB   . LYS A 1 67  ? -40.88  -2.406  10.29   1 60.252  ? 67  LYS A CB   1 ? 
ATOM   981  C CG   . LYS A 1 67  ? -41.635 -3.696  10.494  1 65.187  ? 67  LYS A CG   1 ? 
ATOM   982  C CD   . LYS A 1 67  ? -41.288 -4.426  11.787  1 69.804  ? 67  LYS A CD   1 ? 
ATOM   983  C CE   . LYS A 1 67  ? -41.942 -5.779  11.855  1 76.945  ? 67  LYS A CE   1 ? 
ATOM   984  N NZ   . LYS A 1 67  ? -41.224 -6.711  12.732  1 80.256  ? 67  LYS A NZ   1 ? 
ATOM   985  H H    . LYS A 1 67  ? -39.874 -0.241  9.458   1 62.158  ? 67  LYS A H    1 c 
ATOM   986  H HA   . LYS A 1 67  ? -40.517 -2.493  8.266   1 64.894  ? 67  LYS A HA   1 c 
ATOM   987  H HB2  . LYS A 1 67  ? -39.934 -2.558  10.504  1 62.683  ? 67  LYS A HB2  1 c 
ATOM   988  H HB3  . LYS A 1 67  ? -41.227 -1.736  10.917  1 62.683  ? 67  LYS A HB3  1 c 
ATOM   989  H HG2  . LYS A 1 67  ? -42.598 -3.504  10.489  1 65.072  ? 67  LYS A HG2  1 c 
ATOM   990  H HG3  . LYS A 1 67  ? -41.44  -4.287  9.737   1 65.194  ? 67  LYS A HG3  1 c 
ATOM   991  H HD2  . LYS A 1 67  ? -40.314 -4.536  11.845  1 70.292  ? 67  LYS A HD2  1 c 
ATOM   992  H HD3  . LYS A 1 67  ? -41.583 -3.886  12.553  1 70.292  ? 67  LYS A HD3  1 c 
ATOM   993  H HE2  . LYS A 1 67  ? -42.852 -5.677  12.187  1 75.983  ? 67  LYS A HE2  1 c 
ATOM   994  H HE3  . LYS A 1 67  ? -41.991 -6.169  10.964  1 75.876  ? 67  LYS A HE3  1 c 
ATOM   995  H HZ1  . LYS A 1 67  ? -41.099 -6.332  13.545  1 79.179  ? 67  LYS A HZ1  1 c 
ATOM   996  H HZ2  . LYS A 1 67  ? -40.418 -6.913  12.369  1 79.212  ? 67  LYS A HZ2  1 c 
ATOM   997  H HZ3  . LYS A 1 67  ? -41.706 -7.472  12.829  1 79.212  ? 67  LYS A HZ3  1 c 
ATOM   998  N N    . ASN A 1 68  ? -43.184 -0.774  8.911   1 77.029  ? 68  ASN A N    1 ? 
ATOM   999  C CA   . ASN A 1 68  ? -44.617 -0.703  8.65    1 78.398  ? 68  ASN A CA   1 ? 
ATOM   1000 C C    . ASN A 1 68  ? -44.884 -0.313  7.196   1 67.648  ? 68  ASN A C    1 ? 
ATOM   1001 O O    . ASN A 1 68  ? -45.806 -0.863  6.595   1 60.524  ? 68  ASN A O    1 ? 
ATOM   1002 C CB   . ASN A 1 68  ? -45.344 0.195   9.648   1 82.505  ? 68  ASN A CB   1 ? 
ATOM   1003 C CG   . ASN A 1 68  ? -45.599 -0.521  10.953  1 86.592  ? 68  ASN A CG   1 ? 
ATOM   1004 O OD1  . ASN A 1 68  ? -46.264 -1.567  10.978  1 81.526  ? 68  ASN A OD1  1 ? 
ATOM   1005 N ND2  . ASN A 1 68  ? -45.071 0.017   12.041  1 88.736  ? 68  ASN A ND2  1 ? 
ATOM   1006 H H    . ASN A 1 68  ? -42.796 -0.136  9.437   1 75.262  ? 68  ASN A H    1 c 
ATOM   1007 H HA   . ASN A 1 68  ? -44.979 -1.61   8.77    1 76.644  ? 68  ASN A HA   1 c 
ATOM   1008 H HB2  . ASN A 1 68  ? -44.807 0.995   9.816   1 82.47   ? 68  ASN A HB2  1 c 
ATOM   1009 H HB3  . ASN A 1 68  ? -46.199 0.478   9.265   1 82.381  ? 68  ASN A HB3  1 c 
ATOM   1010 H HD21 . ASN A 1 68  ? -45.562 0.106   12.774  1 88.06   ? 68  ASN A HD21 1 c 
ATOM   1011 H HD22 . ASN A 1 68  ? -44.226 0.288   12.035  1 88.025  ? 68  ASN A HD22 1 c 
ATOM   1012 N N    . GLU A 1 69  ? -44.098 0.644   6.668   1 66.454  ? 69  GLU A N    1 ? 
ATOM   1013 C CA   . GLU A 1 69  ? -44.058 0.939   5.24    1 72.131  ? 69  GLU A CA   1 ? 
ATOM   1014 C C    . GLU A 1 69  ? -43.974 -0.356  4.416   1 73.037  ? 69  GLU A C    1 ? 
ATOM   1015 O O    . GLU A 1 69  ? -44.86  -0.625  3.602   1 70.386  ? 69  GLU A O    1 ? 
ATOM   1016 C CB   . GLU A 1 69  ? -42.918 1.906   4.904   1 74.297  ? 69  GLU A CB   1 ? 
ATOM   1017 C CG   . GLU A 1 69  ? -43.249 3.372   5.194   1 73.671  ? 69  GLU A CG   1 ? 
ATOM   1018 C CD   . GLU A 1 69  ? -42.148 4.371   4.862   1 76.969  ? 69  GLU A CD   1 ? 
ATOM   1019 O OE1  . GLU A 1 69  ? -40.963 4.031   5.101   1 75.669  ? 69  GLU A OE1  1 ? 
ATOM   1020 O OE2  . GLU A 1 69  ? -42.452 5.502   4.403   1 78.311  ? 69  GLU A OE2  1 ? 
ATOM   1021 H H    . GLU A 1 69  ? -43.578 1.145   7.228   1 68.181  ? 69  GLU A H    1 c 
ATOM   1022 H HA   . GLU A 1 69  ? -44.908 1.391   5.004   1 71.542  ? 69  GLU A HA   1 c 
ATOM   1023 H HB2  . GLU A 1 69  ? -42.123 1.649   5.406   1 73.518  ? 69  GLU A HB2  1 c 
ATOM   1024 H HB3  . GLU A 1 69  ? -42.706 1.824   3.951   1 73.627  ? 69  GLU A HB3  1 c 
ATOM   1025 H HG2  . GLU A 1 69  ? -44.049 3.62    4.682   1 74.55   ? 69  GLU A HG2  1 c 
ATOM   1026 H HG3  . GLU A 1 69  ? -43.476 3.466   6.142   1 74.517  ? 69  GLU A HG3  1 c 
ATOM   1027 N N    . LEU A 1 70  ? -42.93  -1.171  4.654   1 69.345  ? 70  LEU A N    1 ? 
ATOM   1028 C CA   . LEU A 1 70  ? -42.705 -2.397  3.895   1 61.249  ? 70  LEU A CA   1 ? 
ATOM   1029 C C    . LEU A 1 70  ? -43.904 -3.328  4.023   1 58.381  ? 70  LEU A C    1 ? 
ATOM   1030 O O    . LEU A 1 70  ? -44.373 -3.856  3.017   1 59.874  ? 70  LEU A O    1 ? 
ATOM   1031 C CB   . LEU A 1 70  ? -41.432 -3.106  4.35    1 64.326  ? 70  LEU A CB   1 ? 
ATOM   1032 C CG   . LEU A 1 70  ? -41.129 -4.442  3.66    1 68.033  ? 70  LEU A CG   1 ? 
ATOM   1033 C CD1  . LEU A 1 70  ? -40.818 -4.196  2.191   1 64.911  ? 70  LEU A CD1  1 ? 
ATOM   1034 C CD2  . LEU A 1 70  ? -39.989 -5.194  4.347   1 66.46   ? 70  LEU A CD2  1 ? 
ATOM   1035 H H    . LEU A 1 70  ? -42.339 -0.951  5.316   1 68.261  ? 70  LEU A H    1 c 
ATOM   1036 H HA   . LEU A 1 70  ? -42.609 -2.147  2.941   1 62.768  ? 70  LEU A HA   1 c 
ATOM   1037 H HB2  . LEU A 1 70  ? -40.672 -2.499  4.201   1 64.431  ? 70  LEU A HB2  1 c 
ATOM   1038 H HB3  . LEU A 1 70  ? -41.5   -3.266  5.319   1 64.424  ? 70  LEU A HB3  1 c 
ATOM   1039 H HG   . LEU A 1 70  ? -41.934 -5.01   3.714   1 66.346  ? 70  LEU A HG   1 c 
ATOM   1040 H HD11 . LEU A 1 70  ? -41.635 -3.956  1.722   1 65.77   ? 70  LEU A HD11 1 c 
ATOM   1041 H HD12 . LEU A 1 70  ? -40.446 -5.003  1.798   1 65.806  ? 70  LEU A HD12 1 c 
ATOM   1042 H HD13 . LEU A 1 70  ? -40.175 -3.472  2.11    1 65.789  ? 70  LEU A HD13 1 c 
ATOM   1043 H HD21 . LEU A 1 70  ? -40.23  -5.377  5.27    1 66.918  ? 70  LEU A HD21 1 c 
ATOM   1044 H HD22 . LEU A 1 70  ? -39.182 -4.653  4.324   1 66.918  ? 70  LEU A HD22 1 c 
ATOM   1045 H HD23 . LEU A 1 70  ? -39.828 -6.033  3.883   1 66.918  ? 70  LEU A HD23 1 c 
ATOM   1046 N N    . LEU A 1 71  ? -44.373 -3.521  5.267   1 62.635  ? 71  LEU A N    1 ? 
ATOM   1047 C CA   . LEU A 1 71  ? -45.479 -4.419  5.575   1 63.838  ? 71  LEU A CA   1 ? 
ATOM   1048 C C    . LEU A 1 71  ? -46.781 -3.915  4.953   1 62.555  ? 71  LEU A C    1 ? 
ATOM   1049 O O    . LEU A 1 71  ? -47.634 -4.713  4.562   1 62.706  ? 71  LEU A O    1 ? 
ATOM   1050 C CB   . LEU A 1 71  ? -45.606 -4.576  7.09    1 70.016  ? 71  LEU A CB   1 ? 
ATOM   1051 C CG   . LEU A 1 71  ? -44.713 -5.634  7.751   1 79.16   ? 71  LEU A CG   1 ? 
ATOM   1052 C CD1  . LEU A 1 71  ? -43.227 -5.373  7.617   1 81.831  ? 71  LEU A CD1  1 ? 
ATOM   1053 C CD2  . LEU A 1 71  ? -45.07  -5.765  9.23    1 75.745  ? 71  LEU A CD2  1 ? 
ATOM   1054 H H    . LEU A 1 71  ? -43.975 -3.072  5.957   1 62.149  ? 71  LEU A H    1 c 
ATOM   1055 H HA   . LEU A 1 71  ? -45.271 -5.304  5.179   1 64.44   ? 71  LEU A HA   1 c 
ATOM   1056 H HB2  . LEU A 1 71  ? -45.419 -3.705  7.51    1 70.368  ? 71  LEU A HB2  1 c 
ATOM   1057 H HB3  . LEU A 1 71  ? -46.544 -4.796  7.297   1 70.423  ? 71  LEU A HB3  1 c 
ATOM   1058 H HG   . LEU A 1 71  ? -44.904 -6.506  7.318   1 77.238  ? 71  LEU A HG   1 c 
ATOM   1059 H HD11 . LEU A 1 71  ? -43.02  -5.074  6.719   1 80.513  ? 71  LEU A HD11 1 c 
ATOM   1060 H HD12 . LEU A 1 71  ? -42.74  -6.194  7.8     1 80.768  ? 71  LEU A HD12 1 c 
ATOM   1061 H HD13 . LEU A 1 71  ? -42.962 -4.699  8.255   1 80.579  ? 71  LEU A HD13 1 c 
ATOM   1062 H HD21 . LEU A 1 71  ? -45.994 -6.056  9.317   1 76.733  ? 71  LEU A HD21 1 c 
ATOM   1063 H HD22 . LEU A 1 71  ? -44.959 -4.905  9.669   1 76.733  ? 71  LEU A HD22 1 c 
ATOM   1064 H HD23 . LEU A 1 71  ? -44.485 -6.419  9.649   1 76.733  ? 71  LEU A HD23 1 c 
ATOM   1065 N N    . SER A 1 72  ? -46.935 -2.586  4.898   1 55.796  ? 72  SER A N    1 ? 
ATOM   1066 C CA   . SER A 1 72  ? -48.078 -1.967  4.238   1 65.097  ? 72  SER A CA   1 ? 
ATOM   1067 C C    . SER A 1 72  ? -48.041 -2.272  2.739   1 58.198  ? 72  SER A C    1 ? 
ATOM   1068 O O    . SER A 1 72  ? -49.053 -2.647  2.153   1 57.698  ? 72  SER A O    1 ? 
ATOM   1069 C CB   . SER A 1 72  ? -48.12  -0.456  4.511   1 63.584  ? 72  SER A CB   1 ? 
ATOM   1070 O OG   . SER A 1 72  ? -49.199 0.168   3.828   1 69.973  ? 72  SER A OG   1 ? 
ATOM   1071 H H    . SER A 1 72  ? -46.32  -2.045  5.301   1 59.483  ? 72  SER A H    1 c 
ATOM   1072 H HA   . SER A 1 72  ? -48.902 -2.371  4.612   1 61.626  ? 72  SER A HA   1 c 
ATOM   1073 H HB2  . SER A 1 72  ? -48.216 -0.306  5.471   1 65.379  ? 72  SER A HB2  1 c 
ATOM   1074 H HB3  . SER A 1 72  ? -47.282 -0.052  4.225   1 65.421  ? 72  SER A HB3  1 c 
ATOM   1075 N N    . LEU A 1 73  ? -46.846 -2.135  2.147   1 58.644  ? 73  LEU A N    1 ? 
ATOM   1076 C CA   . LEU A 1 73  ? -46.634 -2.361  0.725   1 55.444  ? 73  LEU A CA   1 ? 
ATOM   1077 C C    . LEU A 1 73  ? -46.968 -3.797  0.337   1 49.895  ? 73  LEU A C    1 ? 
ATOM   1078 O O    . LEU A 1 73  ? -47.544 -4.029  -0.717  1 54.449  ? 73  LEU A O    1 ? 
ATOM   1079 C CB   . LEU A 1 73  ? -45.197 -1.989  0.369   1 55.824  ? 73  LEU A CB   1 ? 
ATOM   1080 C CG   . LEU A 1 73  ? -44.741 -2.315  -1.057  1 56.843  ? 73  LEU A CG   1 ? 
ATOM   1081 C CD1  . LEU A 1 73  ? -45.703 -1.828  -2.134  1 63.905  ? 73  LEU A CD1  1 ? 
ATOM   1082 C CD2  . LEU A 1 73  ? -43.374 -1.697  -1.249  1 54.946  ? 73  LEU A CD2  1 ? 
ATOM   1083 H H    . LEU A 1 73  ? -46.133 -1.87   2.653   1 57.803  ? 73  LEU A H    1 c 
ATOM   1084 H HA   . LEU A 1 73  ? -47.25  -1.762  0.231   1 55.118  ? 73  LEU A HA   1 c 
ATOM   1085 H HB2  . LEU A 1 73  ? -45.088 -1.021  0.515   1 55.967  ? 73  LEU A HB2  1 c 
ATOM   1086 H HB3  . LEU A 1 73  ? -44.594 -2.448  0.995   1 56.001  ? 73  LEU A HB3  1 c 
ATOM   1087 H HG   . LEU A 1 73  ? -44.648 -3.299  -1.141  1 57.492  ? 73  LEU A HG   1 c 
ATOM   1088 H HD11 . LEU A 1 73  ? -46.296 -2.551  -2.393  1 61.644  ? 73  LEU A HD11 1 c 
ATOM   1089 H HD12 . LEU A 1 73  ? -45.2   -1.534  -2.913  1 61.612  ? 73  LEU A HD12 1 c 
ATOM   1090 H HD13 . LEU A 1 73  ? -46.228 -1.085  -1.793  1 61.592  ? 73  LEU A HD13 1 c 
ATOM   1091 H HD21 . LEU A 1 73  ? -42.783 -1.981  -0.531  1 55.513  ? 73  LEU A HD21 1 c 
ATOM   1092 H HD22 . LEU A 1 73  ? -43.451 -0.728  -1.24   1 55.512  ? 73  LEU A HD22 1 c 
ATOM   1093 H HD23 . LEU A 1 73  ? -43.004 -1.982  -2.102  1 55.542  ? 73  LEU A HD23 1 c 
ATOM   1094 N N    . ILE A 1 74  ? -46.63  -4.75   1.204   1 60.009  ? 74  ILE A N    1 ? 
ATOM   1095 C CA   . ILE A 1 74  ? -46.852 -6.168  0.943   1 61.176  ? 74  ILE A CA   1 ? 
ATOM   1096 C C    . ILE A 1 74  ? -48.341 -6.482  1.04    1 58.334  ? 74  ILE A C    1 ? 
ATOM   1097 O O    . ILE A 1 74  ? -48.868 -7.272  0.259   1 63.06   ? 74  ILE A O    1 ? 
ATOM   1098 C CB   . ILE A 1 74  ? -46.015 -7.028  1.911   1 57.582  ? 74  ILE A CB   1 ? 
ATOM   1099 C CG1  . ILE A 1 74  ? -44.508 -6.888  1.609   1 60.262  ? 74  ILE A CG1  1 ? 
ATOM   1100 C CG2  . ILE A 1 74  ? -46.474 -8.489  1.899   1 53.904  ? 74  ILE A CG2  1 ? 
ATOM   1101 C CD1  . ILE A 1 74  ? -43.596 -7.017  2.816   1 63.499  ? 74  ILE A CD1  1 ? 
ATOM   1102 H H    . ILE A 1 74  ? -46.23  -4.512  1.991   1 57.664  ? 74  ILE A H    1 c 
ATOM   1103 H HA   . ILE A 1 74  ? -46.556 -6.361  0.032   1 59.64   ? 74  ILE A HA   1 c 
ATOM   1104 H HB   . ILE A 1 74  ? -46.165 -6.682  2.813   1 58.029  ? 74  ILE A HB   1 c 
ATOM   1105 H HG12 . ILE A 1 74  ? -44.258 -7.574  0.957   1 60.333  ? 74  ILE A HG12 1 c 
ATOM   1106 H HG13 . ILE A 1 74  ? -44.349 -6.016  1.194   1 60.368  ? 74  ILE A HG13 1 c 
ATOM   1107 H HG21 . ILE A 1 74  ? -45.754 -9.057  2.22    1 55.012  ? 74  ILE A HG21 1 c 
ATOM   1108 H HG22 . ILE A 1 74  ? -46.708 -8.752  0.993   1 55.056  ? 74  ILE A HG22 1 c 
ATOM   1109 H HG23 . ILE A 1 74  ? -47.248 -8.595  2.478   1 55      ? 74  ILE A HG23 1 c 
ATOM   1110 H HD11 . ILE A 1 74  ? -43.859 -6.378  3.504   1 62.545  ? 74  ILE A HD11 1 c 
ATOM   1111 H HD12 . ILE A 1 74  ? -42.675 -6.844  2.545   1 62.555  ? 74  ILE A HD12 1 c 
ATOM   1112 H HD13 . ILE A 1 74  ? -43.662 -7.923  3.175   1 62.534  ? 74  ILE A HD13 1 c 
ATOM   1113 N N    . ALA A 1 75  ? -48.987 -5.922  2.062   1 65.85   ? 75  ALA A N    1 ? 
ATOM   1114 C CA   . ALA A 1 75  ? -50.416 -6.105  2.258   1 64.174  ? 75  ALA A CA   1 ? 
ATOM   1115 C C    . ALA A 1 75  ? -51.169 -5.516  1.07    1 53.62   ? 75  ALA A C    1 ? 
ATOM   1116 O O    . ALA A 1 75  ? -52.09  -6.136  0.551   1 51.286  ? 75  ALA A O    1 ? 
ATOM   1117 C CB   . ALA A 1 75  ? -50.832 -5.469  3.567   1 71.351  ? 75  ALA A CB   1 ? 
ATOM   1118 H H    . ALA A 1 75  ? -48.523 -5.421  2.67    1 63.612  ? 75  ALA A H    1 c 
ATOM   1119 H HA   . ALA A 1 75  ? -50.604 -7.084  2.296   1 63.624  ? 75  ALA A HA   1 c 
ATOM   1120 H HB1  . ALA A 1 75  ? -50.338 -5.875  4.3     1 69.145  ? 75  ALA A HB1  1 c 
ATOM   1121 H HB2  . ALA A 1 75  ? -50.643 -4.516  3.542   1 69.145  ? 75  ALA A HB2  1 c 
ATOM   1122 H HB3  . ALA A 1 75  ? -51.784 -5.604  3.709   1 69.145  ? 75  ALA A HB3  1 c 
ATOM   1123 N N    . TYR A 1 76  ? -50.727 -4.342  0.612   1 57.137  ? 76  TYR A N    1 ? 
ATOM   1124 C CA   . TYR A 1 76  ? -51.308 -3.717  -0.567  1 64.526  ? 76  TYR A CA   1 ? 
ATOM   1125 C C    . TYR A 1 76  ? -51.169 -4.617  -1.802  1 63.246  ? 76  TYR A C    1 ? 
ATOM   1126 O O    . TYR A 1 76  ? -52.154 -4.884  -2.498  1 66.301  ? 76  TYR A O    1 ? 
ATOM   1127 C CB   . TYR A 1 76  ? -50.664 -2.34   -0.751  1 63.823  ? 76  TYR A CB   1 ? 
ATOM   1128 C CG   . TYR A 1 76  ? -51.345 -1.465  -1.796  1 70.75   ? 76  TYR A CG   1 ? 
ATOM   1129 C CD1  . TYR A 1 76  ? -52.484 -0.72   -1.489  1 74.477  ? 76  TYR A CD1  1 ? 
ATOM   1130 C CD2  . TYR A 1 76  ? -50.846 -1.382  -3.091  1 70.518  ? 76  TYR A CD2  1 ? 
ATOM   1131 C CE1  . TYR A 1 76  ? -53.108 0.075   -2.441  1 75.396  ? 76  TYR A CE1  1 ? 
ATOM   1132 C CE2  . TYR A 1 76  ? -51.458 -0.589  -4.051  1 76.728  ? 76  TYR A CE2  1 ? 
ATOM   1133 C CZ   . TYR A 1 76  ? -52.59  0.144   -3.726  1 77.526  ? 76  TYR A CZ   1 ? 
ATOM   1134 O OH   . TYR A 1 76  ? -53.169 0.931   -4.676  1 67.789  ? 76  TYR A OH   1 ? 
ATOM   1135 H H    . TYR A 1 76  ? -50.053 -3.909  1.053   1 58.03   ? 76  TYR A H    1 c 
ATOM   1136 H HA   . TYR A 1 76  ? -52.277 -3.581  -0.393  1 62.654  ? 76  TYR A HA   1 c 
ATOM   1137 H HB2  . TYR A 1 76  ? -50.679 -1.87   0.113   1 65.437  ? 76  TYR A HB2  1 c 
ATOM   1138 H HB3  . TYR A 1 76  ? -49.724 -2.467  -1.007  1 65.43   ? 76  TYR A HB3  1 c 
ATOM   1139 H HD1  . TYR A 1 76  ? -52.843 -0.761  -0.617  1 73.754  ? 76  TYR A HD1  1 c 
ATOM   1140 H HD2  . TYR A 1 76  ? -50.076 -1.875  -3.323  1 71.99   ? 76  TYR A HD2  1 c 
ATOM   1141 H HE1  . TYR A 1 76  ? -53.873 0.575   -2.213  1 75.534  ? 76  TYR A HE1  1 c 
ATOM   1142 H HE2  . TYR A 1 76  ? -51.099 -0.542  -4.919  1 75.284  ? 76  TYR A HE2  1 c 
ATOM   1143 N N    . SER A 1 77  ? -49.944 -5.078  -2.073  1 61.93   ? 77  SER A N    1 ? 
ATOM   1144 C CA   . SER A 1 77  ? -49.676 -5.944  -3.218  1 57.488  ? 77  SER A CA   1 ? 
ATOM   1145 C C    . SER A 1 77  ? -50.532 -7.21   -3.161  1 51.151  ? 77  SER A C    1 ? 
ATOM   1146 O O    . SER A 1 77  ? -51.157 -7.57   -4.155  1 52.953  ? 77  SER A O    1 ? 
ATOM   1147 C CB   . SER A 1 77  ? -48.201 -6.284  -3.322  1 53.147  ? 77  SER A CB   1 ? 
ATOM   1148 O OG   . SER A 1 77  ? -47.392 -5.115  -3.34   1 49.832  ? 77  SER A OG   1 ? 
ATOM   1149 H H    . SER A 1 77  ? -49.247 -4.842  -1.529  1 61.146  ? 77  SER A H    1 c 
ATOM   1150 H HA   . SER A 1 77  ? -49.932 -5.446  -4.034  1 56.179  ? 77  SER A HA   1 c 
ATOM   1151 H HB2  . SER A 1 77  ? -47.946 -6.842  -2.563  1 53.299  ? 77  SER A HB2  1 c 
ATOM   1152 H HB3  . SER A 1 77  ? -48.045 -6.796  -4.137  1 53.322  ? 77  SER A HB3  1 c 
ATOM   1153 N N    . ASN A 1 78  ? -50.595 -7.864  -1.993  1 53.701  ? 78  ASN A N    1 ? 
ATOM   1154 C CA   . ASN A 1 78  ? -51.345 -9.109  -1.858  1 59.106  ? 78  ASN A CA   1 ? 
ATOM   1155 C C    . ASN A 1 78  ? -52.829 -8.883  -2.149  1 64.222  ? 78  ASN A C    1 ? 
ATOM   1156 O O    . ASN A 1 78  ? -53.478 -9.745  -2.752  1 67.649  ? 78  ASN A O    1 ? 
ATOM   1157 C CB   . ASN A 1 78  ? -51.121 -9.774  -0.5    1 61.628  ? 78  ASN A CB   1 ? 
ATOM   1158 C CG   . ASN A 1 78  ? -49.739 -10.377 -0.334  1 67.793  ? 78  ASN A CG   1 ? 
ATOM   1159 O OD1  . ASN A 1 78  ? -49.45  -10.95  0.719   1 67.961  ? 78  ASN A OD1  1 ? 
ATOM   1160 N ND2  . ASN A 1 78  ? -48.859 -10.267 -1.32   1 59.328  ? 78  ASN A ND2  1 ? 
ATOM   1161 H H    . ASN A 1 78  ? -50.155 -7.534  -1.264  1 54.349  ? 78  ASN A H    1 c 
ATOM   1162 H HA   . ASN A 1 78  ? -51.01  -9.732  -2.542  1 59.336  ? 78  ASN A HA   1 c 
ATOM   1163 H HB2  . ASN A 1 78  ? -51.261 -9.109  0.203   1 62.399  ? 78  ASN A HB2  1 c 
ATOM   1164 H HB3  . ASN A 1 78  ? -51.788 -10.479 -0.379  1 62.407  ? 78  ASN A HB3  1 c 
ATOM   1165 H HD21 . ASN A 1 78  ? -48.529 -10.993 -1.704  1 61.894  ? 78  ASN A HD21 1 c 
ATOM   1166 H HD22 . ASN A 1 78  ? -48.57  -9.469  -1.575  1 61.764  ? 78  ASN A HD22 1 c 
ATOM   1167 N N    . ASP A 1 79  ? -53.354 -7.716  -1.743  1 71.449  ? 79  ASP A N    1 ? 
ATOM   1168 C CA   . ASP A 1 79  ? -54.757 -7.379  -1.96   1 77.703  ? 79  ASP A CA   1 ? 
ATOM   1169 C C    . ASP A 1 79  ? -55.065 -7.318  -3.46   1 69.514  ? 79  ASP A C    1 ? 
ATOM   1170 O O    . ASP A 1 79  ? -56.184 -7.618  -3.866  1 69.287  ? 79  ASP A O    1 ? 
ATOM   1171 C CB   . ASP A 1 79  ? -55.156 -6.111  -1.21   1 83.662  ? 79  ASP A CB   1 ? 
ATOM   1172 C CG   . ASP A 1 79  ? -56.598 -5.649  -1.398  1 93.906  ? 79  ASP A CG   1 ? 
ATOM   1173 O OD1  . ASP A 1 79  ? -57.521 -6.419  -1.052  1 94.018  ? 79  ASP A OD1  1 ? 
ATOM   1174 O OD2  . ASP A 1 79  ? -56.793 -4.524  -1.906  1 106.801 ? 79  ASP A OD2  1 ? 
ATOM   1175 H H    . ASP A 1 79  ? -52.826 -7.114  -1.302  1 70.833  ? 79  ASP A H    1 c 
ATOM   1176 H HA   . ASP A 1 79  ? -55.299 -8.103  -1.574  1 75.956  ? 79  ASP A HA   1 c 
ATOM   1177 H HB2  . ASP A 1 79  ? -55.01  -6.26   -0.252  1 84.478  ? 79  ASP A HB2  1 c 
ATOM   1178 H HB3  . ASP A 1 79  ? -54.564 -5.383  -1.491  1 84.491  ? 79  ASP A HB3  1 c 
ATOM   1179 N N    . LYS A 1 80  ? -54.067 -6.954  -4.274  1 65.116  ? 80  LYS A N    1 ? 
ATOM   1180 C CA   . LYS A 1 80  ? -54.207 -6.911  -5.722  1 65.562  ? 80  LYS A CA   1 ? 
ATOM   1181 C C    . LYS A 1 80  ? -53.732 -8.206  -6.393  1 67.749  ? 80  LYS A C    1 ? 
ATOM   1182 O O    . LYS A 1 80  ? -53.46  -8.203  -7.598  1 64.296  ? 80  LYS A O    1 ? 
ATOM   1183 C CB   . LYS A 1 80  ? -53.455 -5.653  -6.172  1 71.107  ? 80  LYS A CB   1 ? 
ATOM   1184 C CG   . LYS A 1 80  ? -54.109 -4.369  -5.667  1 77.693  ? 80  LYS A CG   1 ? 
ATOM   1185 C CD   . LYS A 1 80  ? -53.554 -3.063  -6.219  1 83.913  ? 80  LYS A CD   1 ? 
ATOM   1186 C CE   . LYS A 1 80  ? -54.449 -1.908  -5.868  1 86.597  ? 80  LYS A CE   1 ? 
ATOM   1187 N NZ   . LYS A 1 80  ? -55.714 -1.882  -6.609  1 86.122  ? 80  LYS A NZ   1 ? 
ATOM   1188 H H    . LYS A 1 80  ? -53.271 -6.695  -3.911  1 66.316  ? 80  LYS A H    1 c 
ATOM   1189 H HA   . LYS A 1 80  ? -55.164 -6.782  -5.944  1 66.95   ? 80  LYS A HA   1 c 
ATOM   1190 H HB2  . LYS A 1 80  ? -52.53  -5.689  -5.846  1 71.128  ? 80  LYS A HB2  1 c 
ATOM   1191 H HB3  . LYS A 1 80  ? -53.43  -5.627  -7.147  1 70.83   ? 80  LYS A HB3  1 c 
ATOM   1192 H HG2  . LYS A 1 80  ? -55.067 -4.415  -5.877  1 77.538  ? 80  LYS A HG2  1 c 
ATOM   1193 H HG3  . LYS A 1 80  ? -54.029 -4.35   -4.689  1 77.43   ? 80  LYS A HG3  1 c 
ATOM   1194 H HD2  . LYS A 1 80  ? -52.66  -2.906  -5.844  1 83.068  ? 80  LYS A HD2  1 c 
ATOM   1195 H HD3  . LYS A 1 80  ? -53.473 -3.128  -7.195  1 83.085  ? 80  LYS A HD3  1 c 
ATOM   1196 H HE2  . LYS A 1 80  ? -54.649 -1.943  -4.915  1 85.781  ? 80  LYS A HE2  1 c 
ATOM   1197 H HE3  . LYS A 1 80  ? -53.981 -1.079  -6.038  1 85.656  ? 80  LYS A HE3  1 c 
ATOM   1198 H HZ1  . LYS A 1 80  ? -56.312 -2.437  -6.216  1 86.196  ? 80  LYS A HZ1  1 c 
ATOM   1199 H HZ2  . LYS A 1 80  ? -55.584 -2.143  -7.467  1 86.217  ? 80  LYS A HZ2  1 c 
ATOM   1200 H HZ3  . LYS A 1 80  ? -56.049 -1.04   -6.606  1 86.244  ? 80  LYS A HZ3  1 c 
ATOM   1201 N N    . ASP A 1 81  ? -53.66  -9.31   -5.628  1 72.742  ? 81  ASP A N    1 ? 
ATOM   1202 C CA   . ASP A 1 81  ? -53.19  -10.602 -6.117  1 76.339  ? 81  ASP A CA   1 ? 
ATOM   1203 C C    . ASP A 1 81  ? -51.776 -10.516 -6.699  1 65.94   ? 81  ASP A C    1 ? 
ATOM   1204 O O    . ASP A 1 81  ? -51.489 -11.132 -7.724  1 56.602  ? 81  ASP A O    1 ? 
ATOM   1205 C CB   . ASP A 1 81  ? -54.167 -11.208 -7.114  1 80.853  ? 81  ASP A CB   1 ? 
ATOM   1206 C CG   . ASP A 1 81  ? -55.497 -11.636 -6.518  1 92.777  ? 81  ASP A CG   1 ? 
ATOM   1207 O OD1  . ASP A 1 81  ? -55.739 -11.315 -5.336  1 96.742  ? 81  ASP A OD1  1 ? 
ATOM   1208 O OD2  . ASP A 1 81  ? -56.263 -12.321 -7.23   1 99.698  ? 81  ASP A OD2  1 ? 
ATOM   1209 H H    . ASP A 1 81  ? -53.936 -9.266  -4.76   1 72.146  ? 81  ASP A H    1 c 
ATOM   1210 H HA   . ASP A 1 81  ? -53.155 -11.216 -5.349  1 74.519  ? 81  ASP A HA   1 c 
ATOM   1211 H HB2  . ASP A 1 81  ? -54.344 -10.584 -7.847  1 82.157  ? 81  ASP A HB2  1 c 
ATOM   1212 H HB3  . ASP A 1 81  ? -53.77  -12.015 -7.503  1 82.101  ? 81  ASP A HB3  1 c 
ATOM   1213 N N    . ILE A 1 82  ? -50.892 -9.763  -6.038  1 56.937  ? 82  ILE A N    1 ? 
ATOM   1214 C CA   . ILE A 1 82  ? -49.511 -9.646  -6.484  1 59.983  ? 82  ILE A CA   1 ? 
ATOM   1215 C C    . ILE A 1 82  ? -48.611 -10.266 -5.418  1 59.74   ? 82  ILE A C    1 ? 
ATOM   1216 O O    . ILE A 1 82  ? -48.641 -9.834  -4.265  1 50.459  ? 82  ILE A O    1 ? 
ATOM   1217 C CB   . ILE A 1 82  ? -49.119 -8.182  -6.752  1 59.308  ? 82  ILE A CB   1 ? 
ATOM   1218 C CG1  . ILE A 1 82  ? -50.065 -7.481  -7.763  1 66.359  ? 82  ILE A CG1  1 ? 
ATOM   1219 C CG2  . ILE A 1 82  ? -47.653 -8.089  -7.184  1 59.245  ? 82  ILE A CG2  1 ? 
ATOM   1220 C CD1  . ILE A 1 82  ? -50.052 -8.071  -9.165  1 66.78   ? 82  ILE A CD1  1 ? 
ATOM   1221 H H    . ILE A 1 82  ? -51.148 -9.318  -5.282  1 59.841  ? 82  ILE A H    1 c 
ATOM   1222 H HA   . ILE A 1 82  ? -49.401 -10.145 -7.315  1 59.264  ? 82  ILE A HA   1 c 
ATOM   1223 H HB   . ILE A 1 82  ? -49.201 -7.704  -5.906  1 60.573  ? 82  ILE A HB   1 c 
ATOM   1224 H HG12 . ILE A 1 82  ? -50.978 -7.517  -7.416  1 64.756  ? 82  ILE A HG12 1 c 
ATOM   1225 H HG13 . ILE A 1 82  ? -49.81  -6.538  -7.822  1 64.793  ? 82  ILE A HG13 1 c 
ATOM   1226 H HG21 . ILE A 1 82  ? -47.521 -7.286  -7.717  1 59.253  ? 82  ILE A HG21 1 c 
ATOM   1227 H HG22 . ILE A 1 82  ? -47.419 -8.868  -7.715  1 59.115  ? 82  ILE A HG22 1 c 
ATOM   1228 H HG23 . ILE A 1 82  ? -47.082 -8.049  -6.399  1 59.167  ? 82  ILE A HG23 1 c 
ATOM   1229 H HD11 . ILE A 1 82  ? -49.143 -8.312  -9.427  1 66.566  ? 82  ILE A HD11 1 c 
ATOM   1230 H HD12 . ILE A 1 82  ? -50.402 -7.413  -9.792  1 66.512  ? 82  ILE A HD12 1 c 
ATOM   1231 H HD13 . ILE A 1 82  ? -50.615 -8.868  -9.186  1 66.611  ? 82  ILE A HD13 1 c 
ATOM   1232 N N    . LEU A 1 83  ? -47.796 -11.259 -5.816  1 60.256  ? 83  LEU A N    1 ? 
ATOM   1233 C CA   . LEU A 1 83  ? -46.8   -11.824 -4.914  1 55.729  ? 83  LEU A CA   1 ? 
ATOM   1234 C C    . LEU A 1 83  ? -45.595 -10.886 -4.849  1 46.915  ? 83  LEU A C    1 ? 
ATOM   1235 O O    . LEU A 1 83  ? -45.093 -10.43  -5.868  1 49.506  ? 83  LEU A O    1 ? 
ATOM   1236 C CB   . LEU A 1 83  ? -46.4   -13.237 -5.335  1 57.655  ? 83  LEU A CB   1 ? 
ATOM   1237 C CG   . LEU A 1 83  ? -45.182 -13.845 -4.625  1 56.396  ? 83  LEU A CG   1 ? 
ATOM   1238 C CD1  . LEU A 1 83  ? -45.472 -14.111 -3.16   1 54.385  ? 83  LEU A CD1  1 ? 
ATOM   1239 C CD2  . LEU A 1 83  ? -44.74  -15.136 -5.326  1 53.73   ? 83  LEU A CD2  1 ? 
ATOM   1240 H H    . LEU A 1 83  ? -47.863 -11.591 -6.665  1 59.068  ? 83  LEU A H    1 c 
ATOM   1241 H HA   . LEU A 1 83  ? -47.204 -11.875 -4.011  1 55.023  ? 83  LEU A HA   1 c 
ATOM   1242 H HB2  . LEU A 1 83  ? -47.173 -13.83  -5.187  1 56.926  ? 83  LEU A HB2  1 c 
ATOM   1243 H HB3  . LEU A 1 83  ? -46.22  -13.228 -6.303  1 56.937  ? 83  LEU A HB3  1 c 
ATOM   1244 H HG   . LEU A 1 83  ? -44.429 -13.203 -4.679  1 55.685  ? 83  LEU A HG   1 c 
ATOM   1245 H HD11 . LEU A 1 83  ? -45.83  -13.311 -2.748  1 55.022  ? 83  LEU A HD11 1 c 
ATOM   1246 H HD12 . LEU A 1 83  ? -44.653 -14.368 -2.708  1 54.974  ? 83  LEU A HD12 1 c 
ATOM   1247 H HD13 . LEU A 1 83  ? -46.119 -14.831 -3.085  1 55.074  ? 83  LEU A HD13 1 c 
ATOM   1248 H HD21 . LEU A 1 83  ? -44.49  -14.938 -6.244  1 54.497  ? 83  LEU A HD21 1 c 
ATOM   1249 H HD22 . LEU A 1 83  ? -45.472 -15.775 -5.321  1 54.497  ? 83  LEU A HD22 1 c 
ATOM   1250 H HD23 . LEU A 1 83  ? -43.977 -15.515 -4.858  1 54.497  ? 83  LEU A HD23 1 c 
ATOM   1251 N N    . VAL A 1 84  ? -45.135 -10.6   -3.63   1 44.772  ? 84  VAL A N    1 ? 
ATOM   1252 C CA   . VAL A 1 84  ? -43.916 -9.846  -3.419  1 45.872  ? 84  VAL A CA   1 ? 
ATOM   1253 C C    . VAL A 1 84  ? -42.763 -10.821 -3.194  1 47.452  ? 84  VAL A C    1 ? 
ATOM   1254 O O    . VAL A 1 84  ? -42.819 -11.673 -2.308  1 46.588  ? 84  VAL A O    1 ? 
ATOM   1255 C CB   . VAL A 1 84  ? -44.056 -8.888  -2.23   1 52.165  ? 84  VAL A CB   1 ? 
ATOM   1256 C CG1  . VAL A 1 84  ? -42.9   -7.895  -2.178  1 48.283  ? 84  VAL A CG1  1 ? 
ATOM   1257 C CG2  . VAL A 1 84  ? -45.391 -8.165  -2.271  1 57.507  ? 84  VAL A CG2  1 ? 
ATOM   1258 H H    . VAL A 1 84  ? -45.594 -10.896 -2.898  1 45.721  ? 84  VAL A H    1 c 
ATOM   1259 H HA   . VAL A 1 84  ? -43.732 -9.315  -4.217  1 47.101  ? 84  VAL A HA   1 c 
ATOM   1260 H HB   . VAL A 1 84  ? -44.03  -9.432  -1.408  1 51.102  ? 84  VAL A HB   1 c 
ATOM   1261 H HG11 . VAL A 1 84  ? -42.814 -7.452  -3.039  1 49.387  ? 84  VAL A HG11 1 c 
ATOM   1262 H HG12 . VAL A 1 84  ? -42.075 -8.364  -1.972  1 49.391  ? 84  VAL A HG12 1 c 
ATOM   1263 H HG13 . VAL A 1 84  ? -43.071 -7.231  -1.489  1 49.432  ? 84  VAL A HG13 1 c 
ATOM   1264 H HG21 . VAL A 1 84  ? -45.343 -7.357  -1.733  1 55.756  ? 84  VAL A HG21 1 c 
ATOM   1265 H HG22 . VAL A 1 84  ? -46.086 -8.746  -1.917  1 55.76   ? 84  VAL A HG22 1 c 
ATOM   1266 H HG23 . VAL A 1 84  ? -45.605 -7.928  -3.189  1 55.713  ? 84  VAL A HG23 1 c 
ATOM   1267 N N    . ILE A 1 85  ? -41.699 -10.65  -3.983  1 51.362  ? 85  ILE A N    1 ? 
ATOM   1268 C CA   . ILE A 1 85  ? -40.537 -11.519 -3.918  1 49.707  ? 85  ILE A CA   1 ? 
ATOM   1269 C C    . ILE A 1 85  ? -39.372 -10.703 -3.39   1 46.375  ? 85  ILE A C    1 ? 
ATOM   1270 O O    . ILE A 1 85  ? -38.865 -9.842  -4.106  1 53.284  ? 85  ILE A O    1 ? 
ATOM   1271 C CB   . ILE A 1 85  ? -40.217 -12.121 -5.297  1 49.164  ? 85  ILE A CB   1 ? 
ATOM   1272 C CG1  . ILE A 1 85  ? -41.298 -13.098 -5.749  1 45.378  ? 85  ILE A CG1  1 ? 
ATOM   1273 C CG2  . ILE A 1 85  ? -38.843 -12.794 -5.284  1 51.808  ? 85  ILE A CG2  1 ? 
ATOM   1274 C CD1  . ILE A 1 85  ? -41.128 -13.548 -7.194  1 46.087  ? 85  ILE A CD1  1 ? 
ATOM   1275 H H    . ILE A 1 85  ? -41.693 -9.963  -4.586  1 49.973  ? 85  ILE A H    1 c 
ATOM   1276 H HA   . ILE A 1 85  ? -40.722 -12.251 -3.31   1 49.19   ? 85  ILE A HA   1 c 
ATOM   1277 H HB   . ILE A 1 85  ? -40.187 -11.387 -5.943  1 48.985  ? 85  ILE A HB   1 c 
ATOM   1278 H HG12 . ILE A 1 85  ? -41.277 -13.885 -5.167  1 46.382  ? 85  ILE A HG12 1 c 
ATOM   1279 H HG13 . ILE A 1 85  ? -42.174 -12.672 -5.651  1 46.401  ? 85  ILE A HG13 1 c 
ATOM   1280 H HG21 . ILE A 1 85  ? -38.789 -13.451 -5.997  1 50.941  ? 85  ILE A HG21 1 c 
ATOM   1281 H HG22 . ILE A 1 85  ? -38.704 -13.239 -4.431  1 50.966  ? 85  ILE A HG22 1 c 
ATOM   1282 H HG23 . ILE A 1 85  ? -38.149 -12.126 -5.416  1 50.971  ? 85  ILE A HG23 1 c 
ATOM   1283 H HD11 . ILE A 1 85  ? -40.592 -12.899 -7.688  1 45.892  ? 85  ILE A HD11 1 c 
ATOM   1284 H HD12 . ILE A 1 85  ? -42.006 -13.628 -7.614  1 45.881  ? 85  ILE A HD12 1 c 
ATOM   1285 H HD13 . ILE A 1 85  ? -40.682 -14.416 -7.213  1 45.881  ? 85  ILE A HD13 1 c 
ATOM   1286 N N    . PRO A 1 86  ? -38.909 -10.931 -2.142  1 42.994  ? 86  PRO A N    1 ? 
ATOM   1287 C CA   . PRO A 1 86  ? -37.714 -10.256 -1.674  1 42.555  ? 86  PRO A CA   1 ? 
ATOM   1288 C C    . PRO A 1 86  ? -36.475 -10.683 -2.447  1 42.949  ? 86  PRO A C    1 ? 
ATOM   1289 O O    . PRO A 1 86  ? -36.394 -11.817 -2.883  1 45.56   ? 86  PRO A O    1 ? 
ATOM   1290 C CB   . PRO A 1 86  ? -37.633 -10.598 -0.206  1 41.356  ? 86  PRO A CB   1 ? 
ATOM   1291 C CG   . PRO A 1 86  ? -38.498 -11.839 -0.058  1 44.05   ? 86  PRO A CG   1 ? 
ATOM   1292 C CD   . PRO A 1 86  ? -39.528 -11.79  -1.121  1 47.682  ? 86  PRO A CD   1 ? 
ATOM   1293 H HA   . PRO A 1 86  ? -37.837 -9.288  -1.766  1 42.558  ? 86  PRO A HA   1 c 
ATOM   1294 H HB2  . PRO A 1 86  ? -36.712 -10.782 0.062   1 42.259  ? 86  PRO A HB2  1 c 
ATOM   1295 H HB3  . PRO A 1 86  ? -37.976 -9.87   0.338   1 42.391  ? 86  PRO A HB3  1 c 
ATOM   1296 H HG2  . PRO A 1 86  ? -37.953 -12.645 -0.157  1 44.248  ? 86  PRO A HG2  1 c 
ATOM   1297 H HG3  . PRO A 1 86  ? -38.919 -11.862 0.82    1 44.286  ? 86  PRO A HG3  1 c 
ATOM   1298 H HD2  . PRO A 1 86  ? -39.706 -12.68  -1.472  1 45.784  ? 86  PRO A HD2  1 c 
ATOM   1299 H HD3  . PRO A 1 86  ? -40.36  -11.398 -0.794  1 45.73   ? 86  PRO A HD3  1 c 
ATOM   1300 N N    . ASP A 1 87  ? -35.544 -9.744  -2.611  1 42.369  ? 87  ASP A N    1 ? 
ATOM   1301 C CA   . ASP A 1 87  ? -34.304 -9.959  -3.315  1 44.724  ? 87  ASP A CA   1 ? 
ATOM   1302 C C    . ASP A 1 87  ? -33.186 -9.35   -2.48   1 50.791  ? 87  ASP A C    1 ? 
ATOM   1303 O O    . ASP A 1 87  ? -33.017 -8.119  -2.472  1 45.112  ? 87  ASP A O    1 ? 
ATOM   1304 C CB   . ASP A 1 87  ? -34.409 -9.458  -4.747  1 45.431  ? 87  ASP A CB   1 ? 
ATOM   1305 C CG   . ASP A 1 87  ? -33.114 -9.325  -5.529  1 53.411  ? 87  ASP A CG   1 ? 
ATOM   1306 O OD1  . ASP A 1 87  ? -32.024 -9.598  -4.943  1 56.94   ? 87  ASP A OD1  1 ? 
ATOM   1307 O OD2  . ASP A 1 87  ? -33.206 -8.909  -6.718  1 54.914  ? 87  ASP A OD2  1 ? 
ATOM   1308 H H    . ASP A 1 87  ? -35.696 -8.914  -2.26   1 43.075  ? 87  ASP A H    1 c 
ATOM   1309 H HA   . ASP A 1 87  ? -34.151 -10.924 -3.381  1 45.555  ? 87  ASP A HA   1 c 
ATOM   1310 H HB2  . ASP A 1 87  ? -34.994 -10.067 -5.242  1 46.977  ? 87  ASP A HB2  1 c 
ATOM   1311 H HB3  . ASP A 1 87  ? -34.849 -8.587  -4.742  1 46.964  ? 87  ASP A HB3  1 c 
ATOM   1312 N N    . ILE A 1 88  ? -32.433 -10.256 -1.824  1 53.073  ? 88  ILE A N    1 ? 
ATOM   1313 C CA   . ILE A 1 88  ? -31.238 -9.945  -1.047  1 53.976  ? 88  ILE A CA   1 ? 
ATOM   1314 C C    . ILE A 1 88  ? -30.032 -10.592 -1.725  1 54.237  ? 88  ILE A C    1 ? 
ATOM   1315 O O    . ILE A 1 88  ? -29.953 -11.811 -1.847  1 51.439  ? 88  ILE A O    1 ? 
ATOM   1316 C CB   . ILE A 1 88  ? -31.381 -10.39  0.429   1 55.834  ? 88  ILE A CB   1 ? 
ATOM   1317 C CG1  . ILE A 1 88  ? -30.087 -10.129 1.227   1 61.539  ? 88  ILE A CG1  1 ? 
ATOM   1318 C CG2  . ILE A 1 88  ? -31.849 -11.839 0.567   1 54.519  ? 88  ILE A CG2  1 ? 
ATOM   1319 C CD1  . ILE A 1 88  ? -30.276 -10.102 2.738   1 65.036  ? 88  ILE A CD1  1 ? 
ATOM   1320 H H    . ILE A 1 88  ? -32.672 -11.135 -1.893  1 52.617  ? 88  ILE A H    1 c 
ATOM   1321 H HA   . ILE A 1 88  ? -31.114 -8.978  -1.054  1 54.089  ? 88  ILE A HA   1 c 
ATOM   1322 H HB   . ILE A 1 88  ? -32.076 -9.827  0.826   1 56.293  ? 88  ILE A HB   1 c 
ATOM   1323 H HG12 . ILE A 1 88  ? -29.437 -10.827 1.008   1 60.932  ? 88  ILE A HG12 1 c 
ATOM   1324 H HG13 . ILE A 1 88  ? -29.711 -9.271  0.943   1 60.924  ? 88  ILE A HG13 1 c 
ATOM   1325 H HG21 . ILE A 1 88  ? -31.864 -12.086 1.506   1 54.99   ? 88  ILE A HG21 1 c 
ATOM   1326 H HG22 . ILE A 1 88  ? -31.244 -12.431 0.094   1 54.891  ? 88  ILE A HG22 1 c 
ATOM   1327 H HG23 . ILE A 1 88  ? -32.744 -11.932 0.201   1 54.89   ? 88  ILE A HG23 1 c 
ATOM   1328 H HD11 . ILE A 1 88  ? -31.052 -9.555  2.963   1 63.917  ? 88  ILE A HD11 1 c 
ATOM   1329 H HD12 . ILE A 1 88  ? -29.481 -9.724  3.16    1 63.959  ? 88  ILE A HD12 1 c 
ATOM   1330 H HD13 . ILE A 1 88  ? -30.414 -11.011 3.067   1 63.909  ? 88  ILE A HD13 1 c 
ATOM   1331 N N    . ASP A 1 89  ? -29.067 -9.768  -2.12   1 51.684  ? 89  ASP A N    1 ? 
ATOM   1332 C CA   . ASP A 1 89  ? -28.01  -10.235 -2.989  1 53.984  ? 89  ASP A CA   1 ? 
ATOM   1333 C C    . ASP A 1 89  ? -26.844 -10.782 -2.166  1 57.703  ? 89  ASP A C    1 ? 
ATOM   1334 O O    . ASP A 1 89  ? -26.1   -10.008 -1.564  1 55.196  ? 89  ASP A O    1 ? 
ATOM   1335 C CB   . ASP A 1 89  ? -27.573 -9.143  -3.944  1 55.742  ? 89  ASP A CB   1 ? 
ATOM   1336 C CG   . ASP A 1 89  ? -26.947 -9.665  -5.226  1 59.627  ? 89  ASP A CG   1 ? 
ATOM   1337 O OD1  . ASP A 1 89  ? -26.148 -10.63  -5.127  1 55.968  ? 89  ASP A OD1  1 ? 
ATOM   1338 O OD2  . ASP A 1 89  ? -27.272 -9.102  -6.3    1 56.505  ? 89  ASP A OD2  1 ? 
ATOM   1339 H H    . ASP A 1 89  ? -29.058 -8.899  -1.838  1 52.835  ? 89  ASP A H    1 c 
ATOM   1340 H HA   . ASP A 1 89  ? -28.369 -10.958 -3.55   1 54.521  ? 89  ASP A HA   1 c 
ATOM   1341 H HB2  . ASP A 1 89  ? -28.358 -8.608  -4.185  1 56.173  ? 89  ASP A HB2  1 c 
ATOM   1342 H HB3  . ASP A 1 89  ? -26.93  -8.546  -3.506  1 56.201  ? 89  ASP A HB3  1 c 
ATOM   1343 N N    . LEU A 1 90  ? -26.646 -12.113 -2.227  1 56.117  ? 90  LEU A N    1 ? 
ATOM   1344 C CA   . LEU A 1 90  ? -25.514 -12.782 -1.596  1 57.518  ? 90  LEU A CA   1 ? 
ATOM   1345 C C    . LEU A 1 90  ? -24.754 -13.634 -2.612  1 56.208  ? 90  LEU A C    1 ? 
ATOM   1346 O O    . LEU A 1 90  ? -25.358 -14.196 -3.513  1 52.93   ? 90  LEU A O    1 ? 
ATOM   1347 C CB   . LEU A 1 90  ? -26.071 -13.662 -0.48   1 54.771  ? 90  LEU A CB   1 ? 
ATOM   1348 C CG   . LEU A 1 90  ? -26.885 -12.927 0.584   1 51.027  ? 90  LEU A CG   1 ? 
ATOM   1349 C CD1  . LEU A 1 90  ? -27.716 -13.868 1.401   1 52.58   ? 90  LEU A CD1  1 ? 
ATOM   1350 C CD2  . LEU A 1 90  ? -25.943 -12.118 1.44    1 54.073  ? 90  LEU A CD2  1 ? 
ATOM   1351 H H    . LEU A 1 90  ? -27.249 -12.628 -2.681  1 56.72   ? 90  LEU A H    1 c 
ATOM   1352 H HA   . LEU A 1 90  ? -24.913 -12.099 -1.215  1 56.446  ? 90  LEU A HA   1 c 
ATOM   1353 H HB2  . LEU A 1 90  ? -26.643 -14.351 -0.889  1 54.487  ? 90  LEU A HB2  1 c 
ATOM   1354 H HB3  . LEU A 1 90  ? -25.317 -14.119 -0.041  1 54.489  ? 90  LEU A HB3  1 c 
ATOM   1355 H HG   . LEU A 1 90  ? -27.502 -12.299 0.131   1 52.596  ? 90  LEU A HG   1 c 
ATOM   1356 H HD11 . LEU A 1 90  ? -28.329 -14.35  0.82    1 52.112  ? 90  LEU A HD11 1 c 
ATOM   1357 H HD12 . LEU A 1 90  ? -28.224 -13.366 2.06    1 52.111  ? 90  LEU A HD12 1 c 
ATOM   1358 H HD13 . LEU A 1 90  ? -27.137 -14.503 1.856   1 52.111  ? 90  LEU A HD13 1 c 
ATOM   1359 H HD21 . LEU A 1 90  ? -25.571 -11.388 0.917   1 53.195  ? 90  LEU A HD21 1 c 
ATOM   1360 H HD22 . LEU A 1 90  ? -25.222 -12.685 1.761   1 53.178  ? 90  LEU A HD22 1 c 
ATOM   1361 H HD23 . LEU A 1 90  ? -26.428 -11.754 2.2     1 53.163  ? 90  LEU A HD23 1 c 
ATOM   1362 N N    . PRO A 1 91  ? -23.428 -13.853 -2.473  1 54.77   ? 91  PRO A N    1 ? 
ATOM   1363 C CA   . PRO A 1 91  ? -22.603 -13.222 -1.454  1 55.811  ? 91  PRO A CA   1 ? 
ATOM   1364 C C    . PRO A 1 91  ? -21.939 -11.91  -1.863  1 50.699  ? 91  PRO A C    1 ? 
ATOM   1365 O O    . PRO A 1 91  ? -21.339 -11.268 -1.018  1 50.978  ? 91  PRO A O    1 ? 
ATOM   1366 C CB   . PRO A 1 91  ? -21.542 -14.289 -1.199  1 54.889  ? 91  PRO A CB   1 ? 
ATOM   1367 C CG   . PRO A 1 91  ? -21.313 -14.802 -2.603  1 49.967  ? 91  PRO A CG   1 ? 
ATOM   1368 C CD   . PRO A 1 91  ? -22.67  -14.857 -3.235  1 53.279  ? 91  PRO A CD   1 ? 
ATOM   1369 H HA   . PRO A 1 91  ? -23.119 -13.091 -0.635  1 54.515  ? 91  PRO A HA   1 c 
ATOM   1370 H HB2  . PRO A 1 91  ? -20.727 -13.902 -0.822  1 53.9    ? 91  PRO A HB2  1 c 
ATOM   1371 H HB3  . PRO A 1 91  ? -21.88  -14.993 -0.612  1 53.927  ? 91  PRO A HB3  1 c 
ATOM   1372 H HG2  . PRO A 1 91  ? -20.725 -14.201 -3.102  1 51.789  ? 91  PRO A HG2  1 c 
ATOM   1373 H HG3  . PRO A 1 91  ? -20.908 -15.692 -2.584  1 51.794  ? 91  PRO A HG3  1 c 
ATOM   1374 H HD2  . PRO A 1 91  ? -22.634 -14.617 -4.179  1 52.872  ? 91  PRO A HD2  1 c 
ATOM   1375 H HD3  . PRO A 1 91  ? -23.073 -15.742 -3.141  1 52.856  ? 91  PRO A HD3  1 c 
ATOM   1376 N N    . ALA A 1 92  ? -21.95  -11.551 -3.151  1 44.75   ? 92  ALA A N    1 ? 
ATOM   1377 C CA   . ALA A 1 92  ? -21.487 -10.234 -3.556  1 47.695  ? 92  ALA A CA   1 ? 
ATOM   1378 C C    . ALA A 1 92  ? -22.66  -9.247  -3.501  1 45.68   ? 92  ALA A C    1 ? 
ATOM   1379 O O    . ALA A 1 92  ? -23.698 -9.566  -2.906  1 41.681  ? 92  ALA A O    1 ? 
ATOM   1380 C CB   . ALA A 1 92  ? -20.839 -10.318 -4.922  1 49.039  ? 92  ALA A CB   1 ? 
ATOM   1381 H H    . ALA A 1 92  ? -22.24  -12.134 -3.793  1 46.868  ? 92  ALA A H    1 c 
ATOM   1382 H HA   . ALA A 1 92  ? -20.801 -9.926  -2.905  1 47.104  ? 92  ALA A HA   1 c 
ATOM   1383 H HB1  . ALA A 1 92  ? -20.406 -11.181 -5.027  1 48.611  ? 92  ALA A HB1  1 c 
ATOM   1384 H HB2  . ALA A 1 92  ? -21.515 -10.213 -5.613  1 48.617  ? 92  ALA A HB2  1 c 
ATOM   1385 H HB3  . ALA A 1 92  ? -20.175 -9.614  -5.013  1 48.641  ? 92  ALA A HB3  1 c 
ATOM   1386 N N    . HIS A 1 93  ? -22.46  -8.032  -4.059  1 51.549  ? 93  HIS A N    1 ? 
ATOM   1387 C CA   . HIS A 1 93  ? -23.449 -6.957  -4.025  1 54.713  ? 93  HIS A CA   1 ? 
ATOM   1388 C C    . HIS A 1 93  ? -23.969 -6.786  -2.593  1 57.878  ? 93  HIS A C    1 ? 
ATOM   1389 O O    . HIS A 1 93  ? -25.177 -6.66   -2.37   1 59.949  ? 93  HIS A O    1 ? 
ATOM   1390 C CB   . HIS A 1 93  ? -24.556 -7.205  -5.065  1 56.407  ? 93  HIS A CB   1 ? 
ATOM   1391 C CG   . HIS A 1 93  ? -24.084 -7.079  -6.475  1 54.079  ? 93  HIS A CG   1 ? 
ATOM   1392 N ND1  . HIS A 1 93  ? -23.943 -5.86   -7.103  1 54.595  ? 93  HIS A ND1  1 ? 
ATOM   1393 C CD2  . HIS A 1 93  ? -23.653 -8.003  -7.348  1 50.742  ? 93  HIS A CD2  1 ? 
ATOM   1394 C CE1  . HIS A 1 93  ? -23.46  -6.057  -8.326  1 57.998  ? 93  HIS A CE1  1 ? 
ATOM   1395 N NE2  . HIS A 1 93  ? -23.283 -7.363  -8.5    1 52.572  ? 93  HIS A NE2  1 ? 
ATOM   1396 H H    . HIS A 1 93  ? -21.661 -7.862  -4.469  1 50.715  ? 93  HIS A H    1 c 
ATOM   1397 H HA   . HIS A 1 93  ? -22.988 -6.131  -4.282  1 54.986  ? 93  HIS A HA   1 c 
ATOM   1398 H HB2  . HIS A 1 93  ? -24.909 -8.106  -4.93   1 55.453  ? 93  HIS A HB2  1 c 
ATOM   1399 H HB3  . HIS A 1 93  ? -25.284 -6.566  -4.916  1 55.498  ? 93  HIS A HB3  1 c 
ATOM   1400 H HD2  . HIS A 1 93  ? -23.623 -8.929  -7.206  1 51.965  ? 93  HIS A HD2  1 c 
ATOM   1401 H HE1  . HIS A 1 93  ? -23.293 -5.386  -8.965  1 55.862  ? 93  HIS A HE1  1 c 
ATOM   1402 N N    . SER A 1 94  ? -23.039 -6.807  -1.623  1 57.591  ? 94  SER A N    1 ? 
ATOM   1403 C CA   . SER A 1 94  ? -23.382 -6.957  -0.211  1 54.693  ? 94  SER A CA   1 ? 
ATOM   1404 C C    . SER A 1 94  ? -22.765 -5.858  0.652   1 54.791  ? 94  SER A C    1 ? 
ATOM   1405 O O    . SER A 1 94  ? -22.959 -5.887  1.855   1 54.583  ? 94  SER A O    1 ? 
ATOM   1406 C CB   . SER A 1 94  ? -22.996 -8.331  0.289   1 51.806  ? 94  SER A CB   1 ? 
ATOM   1407 O OG   . SER A 1 94  ? -24.034 -9.283  0.081   1 52.24   ? 94  SER A OG   1 ? 
ATOM   1408 H H    . SER A 1 94  ? -22.157 -6.749  -1.853  1 56.943  ? 94  SER A H    1 c 
ATOM   1409 H HA   . SER A 1 94  ? -24.358 -6.874  -0.124  1 54.715  ? 94  SER A HA   1 c 
ATOM   1410 H HB2  . SER A 1 94  ? -22.194 -8.628  -0.176  1 52.659  ? 94  SER A HB2  1 c 
ATOM   1411 H HB3  . SER A 1 94  ? -22.79  -8.288  1.241   1 52.592  ? 94  SER A HB3  1 c 
ATOM   1412 N N    . LYS A 1 95  ? -22.101 -4.863  0.046   1 55.589  ? 95  LYS A N    1 ? 
ATOM   1413 C CA   . LYS A 1 95  ? -21.411 -3.825  0.796   1 68.816  ? 95  LYS A CA   1 ? 
ATOM   1414 C C    . LYS A 1 95  ? -22.384 -3.118  1.734   1 69.809  ? 95  LYS A C    1 ? 
ATOM   1415 O O    . LYS A 1 95  ? -22.032 -2.847  2.878   1 71.373  ? 95  LYS A O    1 ? 
ATOM   1416 C CB   . LYS A 1 95  ? -20.759 -2.784  -0.121  1 70.985  ? 95  LYS A CB   1 ? 
ATOM   1417 C CG   . LYS A 1 95  ? -19.826 -1.791  0.558   1 72.771  ? 95  LYS A CG   1 ? 
ATOM   1418 C CD   . LYS A 1 95  ? -19.115 -0.941  -0.484  1 78.726  ? 95  LYS A CD   1 ? 
ATOM   1419 C CE   . LYS A 1 95  ? -18.171 0.036   0.135   1 87.568  ? 95  LYS A CE   1 ? 
ATOM   1420 N NZ   . LYS A 1 95  ? -17.903 1.15    -0.773  1 88.502  ? 95  LYS A NZ   1 ? 
ATOM   1421 H H    . LYS A 1 95  ? -22.097 -4.81   -0.865  1 58.191  ? 95  LYS A H    1 c 
ATOM   1422 H HA   . LYS A 1 95  ? -20.704 -4.256  1.341   1 66.539  ? 95  LYS A HA   1 c 
ATOM   1423 H HB2  . LYS A 1 95  ? -20.252 -3.255  -0.814  1 70.929  ? 95  LYS A HB2  1 c 
ATOM   1424 H HB3  . LYS A 1 95  ? -21.466 -2.28   -0.569  1 70.779  ? 95  LYS A HB3  1 c 
ATOM   1425 H HG2  . LYS A 1 95  ? -20.348 -1.211  1.155   1 73.647  ? 95  LYS A HG2  1 c 
ATOM   1426 H HG3  . LYS A 1 95  ? -19.164 -2.281  1.092   1 73.659  ? 95  LYS A HG3  1 c 
ATOM   1427 H HD2  . LYS A 1 95  ? -18.616 -1.529  -1.093  1 79.234  ? 95  LYS A HD2  1 c 
ATOM   1428 H HD3  . LYS A 1 95  ? -19.785 -0.453  -1.011  1 79.364  ? 95  LYS A HD3  1 c 
ATOM   1429 H HE2  . LYS A 1 95  ? -18.551 0.385   0.962   1 85.601  ? 95  LYS A HE2  1 c 
ATOM   1430 H HE3  . LYS A 1 95  ? -17.332 -0.41   0.349   1 85.661  ? 95  LYS A HE3  1 c 
ATOM   1431 H HZ1  . LYS A 1 95  ? -18.658 1.637   -0.895  1 88.137  ? 95  LYS A HZ1  1 c 
ATOM   1432 H HZ2  . LYS A 1 95  ? -17.62  0.834   -1.574  1 88.14   ? 95  LYS A HZ2  1 c 
ATOM   1433 H HZ3  . LYS A 1 95  ? -17.26  1.683   -0.421  1 88.185  ? 95  LYS A HZ3  1 c 
ATOM   1434 N N    . GLY A 1 96  ? -23.596 -2.847  1.231   1 69.201  ? 96  GLY A N    1 ? 
ATOM   1435 C CA   . GLY A 1 96  ? -24.619 -2.132  1.972   1 68.765  ? 96  GLY A CA   1 ? 
ATOM   1436 C C    . GLY A 1 96  ? -24.789 -2.673  3.389   1 67.152  ? 96  GLY A C    1 ? 
ATOM   1437 O O    . GLY A 1 96  ? -24.554 -1.935  4.339   1 67.983  ? 96  GLY A O    1 ? 
ATOM   1438 H H    . GLY A 1 96  ? -23.792 -3.111  0.378   1 68.981  ? 96  GLY A H    1 c 
ATOM   1439 H HA2  . GLY A 1 96  ? -24.372 -1.178  2.015   1 68.484  ? 96  GLY A HA2  1 c 
ATOM   1440 H HA3  . GLY A 1 96  ? -25.473 -2.196  1.489   1 68.408  ? 96  GLY A HA3  1 c 
ATOM   1441 N N    . TRP A 1 97  ? -25.139 -3.956  3.526   1 58.561  ? 97  TRP A N    1 ? 
ATOM   1442 C CA   . TRP A 1 97  ? -25.41  -4.51   4.846   1 67.484  ? 97  TRP A CA   1 ? 
ATOM   1443 C C    . TRP A 1 97  ? -24.121 -4.873  5.585   1 70.109  ? 97  TRP A C    1 ? 
ATOM   1444 O O    . TRP A 1 97  ? -24.156 -5.083  6.795   1 63.772  ? 97  TRP A O    1 ? 
ATOM   1445 C CB   . TRP A 1 97  ? -26.371 -5.704  4.785   1 64.687  ? 97  TRP A CB   1 ? 
ATOM   1446 C CG   . TRP A 1 97  ? -25.855 -6.942  4.098   1 76.596  ? 97  TRP A CG   1 ? 
ATOM   1447 C CD1  . TRP A 1 97  ? -25.966 -7.255  2.774   1 73.975  ? 97  TRP A CD1  1 ? 
ATOM   1448 C CD2  . TRP A 1 97  ? -25.212 -8.075  4.722   1 79.47   ? 97  TRP A CD2  1 ? 
ATOM   1449 N NE1  . TRP A 1 97  ? -25.424 -8.487  2.525   1 73.795  ? 97  TRP A NE1  1 ? 
ATOM   1450 C CE2  . TRP A 1 97  ? -24.958 -9.017  3.7     1 77.035  ? 97  TRP A CE2  1 ? 
ATOM   1451 C CE3  . TRP A 1 97  ? -24.82  -8.378  6.033   1 72.435  ? 97  TRP A CE3  1 ? 
ATOM   1452 C CZ2  . TRP A 1 97  ? -24.335 -10.237 3.959   1 76.647  ? 97  TRP A CZ2  1 ? 
ATOM   1453 C CZ3  . TRP A 1 97  ? -24.214 -9.587  6.286   1 69.253  ? 97  TRP A CZ3  1 ? 
ATOM   1454 C CH2  . TRP A 1 97  ? -23.986 -10.506 5.265   1 75.715  ? 97  TRP A CH2  1 ? 
ATOM   1455 H H    . TRP A 1 97  ? -25.21  -4.493  2.79    1 62.622  ? 97  TRP A H    1 c 
ATOM   1456 H HA   . TRP A 1 97  ? -25.867 -3.804  5.377   1 65.672  ? 97  TRP A HA   1 c 
ATOM   1457 H HB2  . TRP A 1 97  ? -26.626 -5.94   5.703   1 67.853  ? 97  TRP A HB2  1 c 
ATOM   1458 H HB3  . TRP A 1 97  ? -27.19  -5.414  4.33    1 67.598  ? 97  TRP A HB3  1 c 
ATOM   1459 H HD1  . TRP A 1 97  ? -26.358 -6.703  2.117   1 74.381  ? 97  TRP A HD1  1 c 
ATOM   1460 H HE1  . TRP A 1 97  ? -25.386 -8.873  1.744   1 74.452  ? 97  TRP A HE1  1 c 
ATOM   1461 H HE3  . TRP A 1 97  ? -24.982 -7.767  6.732   1 73.265  ? 97  TRP A HE3  1 c 
ATOM   1462 H HZ2  . TRP A 1 97  ? -24.177 -10.859 3.271   1 76.292  ? 97  TRP A HZ2  1 c 
ATOM   1463 H HZ3  . TRP A 1 97  ? -23.953 -9.8    7.167   1 71.572  ? 97  TRP A HZ3  1 c 
ATOM   1464 H HH2  . TRP A 1 97  ? -23.558 -11.316 5.466   1 74.319  ? 97  TRP A HH2  1 c 
ATOM   1465 N N    . LEU A 1 98  ? -22.993 -4.964  4.874   1 66.093  ? 98  LEU A N    1 ? 
ATOM   1466 C CA   . LEU A 1 98  ? -21.73  -5.246  5.534   1 70.291  ? 98  LEU A CA   1 ? 
ATOM   1467 C C    . LEU A 1 98  ? -21.274 -4.003  6.304   1 68.123  ? 98  LEU A C    1 ? 
ATOM   1468 O O    . LEU A 1 98  ? -20.819 -4.137  7.434   1 65.234  ? 98  LEU A O    1 ? 
ATOM   1469 C CB   . LEU A 1 98  ? -20.681 -5.75   4.541   1 63.756  ? 98  LEU A CB   1 ? 
ATOM   1470 C CG   . LEU A 1 98  ? -20.919 -7.155  3.968   1 68.606  ? 98  LEU A CG   1 ? 
ATOM   1471 C CD1  . LEU A 1 98  ? -19.899 -7.451  2.873   1 69.564  ? 98  LEU A CD1  1 ? 
ATOM   1472 C CD2  . LEU A 1 98  ? -20.89  -8.241  5.028   1 68.832  ? 98  LEU A CD2  1 ? 
ATOM   1473 H H    . LEU A 1 98  ? -23.008 -4.875  3.965   1 67.85   ? 98  LEU A H    1 c 
ATOM   1474 H HA   . LEU A 1 98  ? -21.891 -5.961  6.2     1 67.816  ? 98  LEU A HA   1 c 
ATOM   1475 H HB2  . LEU A 1 98  ? -20.635 -5.112  3.792   1 66.324  ? 98  LEU A HB2  1 c 
ATOM   1476 H HB3  . LEU A 1 98  ? -19.807 -5.748  4.991   1 66.354  ? 98  LEU A HB3  1 c 
ATOM   1477 H HG   . LEU A 1 98  ? -21.819 -7.17   3.557   1 67.812  ? 98  LEU A HG   1 c 
ATOM   1478 H HD11 . LEU A 1 98  ? -19.93  -6.749  2.201   1 69.236  ? 98  LEU A HD11 1 c 
ATOM   1479 H HD12 . LEU A 1 98  ? -20.106 -8.305  2.457   1 69.267  ? 98  LEU A HD12 1 c 
ATOM   1480 H HD13 . LEU A 1 98  ? -19.008 -7.487  3.26    1 69.269  ? 98  LEU A HD13 1 c 
ATOM   1481 H HD21 . LEU A 1 98  ? -21.726 -8.235  5.524   1 68.76   ? 98  LEU A HD21 1 c 
ATOM   1482 H HD22 . LEU A 1 98  ? -20.152 -8.079  5.64    1 68.765  ? 98  LEU A HD22 1 c 
ATOM   1483 H HD23 . LEU A 1 98  ? -20.773 -9.108  4.605   1 68.771  ? 98  LEU A HD23 1 c 
ATOM   1484 N N    . GLU A 1 99  ? -21.432 -2.811  5.701   1 72.665  ? 99  GLU A N    1 ? 
ATOM   1485 C CA   . GLU A 1 99  ? -21.112 -1.535  6.331   1 74.072  ? 99  GLU A CA   1 ? 
ATOM   1486 C C    . GLU A 1 99  ? -21.954 -1.361  7.594   1 72.504  ? 99  GLU A C    1 ? 
ATOM   1487 O O    . GLU A 1 99  ? -21.461 -0.834  8.583   1 77.632  ? 99  GLU A O    1 ? 
ATOM   1488 C CB   . GLU A 1 99  ? -21.319 -0.377  5.351   1 79.918  ? 99  GLU A CB   1 ? 
ATOM   1489 C CG   . GLU A 1 99  ? -20.323 -0.347  4.192   1 86.414  ? 99  GLU A CG   1 ? 
ATOM   1490 C CD   . GLU A 1 99  ? -18.908 0.079   4.548   1 94.346  ? 99  GLU A CD   1 ? 
ATOM   1491 O OE1  . GLU A 1 99  ? -18.668 0.557   5.68    1 101.696 ? 99  GLU A OE1  1 ? 
ATOM   1492 O OE2  . GLU A 1 99  ? -18.033 -0.079  3.673   1 97.553  ? 99  GLU A OE2  1 ? 
ATOM   1493 H H    . GLU A 1 99  ? -21.744 -2.796  4.842   1 71.968  ? 99  GLU A H    1 c 
ATOM   1494 H HA   . GLU A 1 99  ? -20.157 -1.555  6.595   1 74.607  ? 99  GLU A HA   1 c 
ATOM   1495 H HB2  . GLU A 1 99  ? -22.222 -0.443  4.977   1 79.977  ? 99  GLU A HB2  1 c 
ATOM   1496 H HB3  . GLU A 1 99  ? -21.265 0.468   5.844   1 80.021  ? 99  GLU A HB3  1 c 
ATOM   1497 H HG2  . GLU A 1 99  ? -20.277 -1.239  3.793   1 86.359  ? 99  GLU A HG2  1 c 
ATOM   1498 H HG3  . GLU A 1 99  ? -20.662 0.262   3.502   1 86.574  ? 99  GLU A HG3  1 c 
ATOM   1499 N N    . LEU A 1 100 ? -23.198 -1.854  7.563   1 69.025  ? 100 LEU A N    1 ? 
ATOM   1500 C CA   . LEU A 1 100 ? -24.057 -1.89   8.739   1 72.687  ? 100 LEU A CA   1 ? 
ATOM   1501 C C    . LEU A 1 100 ? -23.481 -2.824  9.798   1 68.433  ? 100 LEU A C    1 ? 
ATOM   1502 O O    . LEU A 1 100 ? -23.544 -2.511  10.98   1 76.359  ? 100 LEU A O    1 ? 
ATOM   1503 C CB   . LEU A 1 100 ? -25.492 -2.287  8.389   1 71.919  ? 100 LEU A CB   1 ? 
ATOM   1504 C CG   . LEU A 1 100 ? -26.447 -1.155  7.985   1 73.693  ? 100 LEU A CG   1 ? 
ATOM   1505 C CD1  . LEU A 1 100 ? -25.819 -0.012  7.198   1 77.469  ? 100 LEU A CD1  1 ? 
ATOM   1506 C CD2  . LEU A 1 100 ? -27.589 -1.76   7.18    1 76.361  ? 100 LEU A CD2  1 ? 
ATOM   1507 H H    . LEU A 1 100 ? -23.534 -2.161  6.77    1 70.716  ? 100 LEU A H    1 c 
ATOM   1508 H HA   . LEU A 1 100 ? -24.07  -0.978  9.126   1 71.149  ? 100 LEU A HA   1 c 
ATOM   1509 H HB2  . LEU A 1 100 ? -25.46  -2.944  7.656   1 72.471  ? 100 LEU A HB2  1 c 
ATOM   1510 H HB3  . LEU A 1 100 ? -25.88  -2.749  9.167   1 72.482  ? 100 LEU A HB3  1 c 
ATOM   1511 H HG   . LEU A 1 100 ? -26.833 -0.772  8.815   1 74.543  ? 100 LEU A HG   1 c 
ATOM   1512 H HD11 . LEU A 1 100 ? -25.291 0.543   7.795   1 76.272  ? 100 LEU A HD11 1 c 
ATOM   1513 H HD12 . LEU A 1 100 ? -26.518 0.527   6.791   1 76.309  ? 100 LEU A HD12 1 c 
ATOM   1514 H HD13 . LEU A 1 100 ? -25.245 -0.374  6.502   1 76.283  ? 100 LEU A HD13 1 c 
ATOM   1515 H HD21 . LEU A 1 100 ? -28.004 -2.475  7.687   1 75.529  ? 100 LEU A HD21 1 c 
ATOM   1516 H HD22 . LEU A 1 100 ? -27.245 -2.114  6.343   1 75.46   ? 100 LEU A HD22 1 c 
ATOM   1517 H HD23 . LEU A 1 100 ? -28.25  -1.074  6.99    1 75.498  ? 100 LEU A HD23 1 c 
ATOM   1518 N N    . ILE A 1 101 ? -22.95  -3.977  9.391   1 74.542  ? 101 ILE A N    1 ? 
ATOM   1519 C CA   . ILE A 1 101 ? -22.341 -4.883  10.351  1 70.248  ? 101 ILE A CA   1 ? 
ATOM   1520 C C    . ILE A 1 101 ? -21.067 -4.239  10.901  1 72.966  ? 101 ILE A C    1 ? 
ATOM   1521 O O    . ILE A 1 101 ? -20.842 -4.326  12.102  1 67.084  ? 101 ILE A O    1 ? 
ATOM   1522 C CB   . ILE A 1 101 ? -22.118 -6.283  9.752   1 72.652  ? 101 ILE A CB   1 ? 
ATOM   1523 C CG1  . ILE A 1 101 ? -23.457 -6.963  9.425   1 71.942  ? 101 ILE A CG1  1 ? 
ATOM   1524 C CG2  . ILE A 1 101 ? -21.254 -7.159  10.671  1 74.29   ? 101 ILE A CG2  1 ? 
ATOM   1525 C CD1  . ILE A 1 101 ? -24.201 -7.542  10.619  1 73.107  ? 101 ILE A CD1  1 ? 
ATOM   1526 H H    . ILE A 1 101 ? -22.991 -4.22   8.511   1 72.037  ? 101 ILE A H    1 c 
ATOM   1527 H HA   . ILE A 1 101 ? -22.963 -4.985  11.096  1 71.991  ? 101 ILE A HA   1 c 
ATOM   1528 H HB   . ILE A 1 101 ? -21.634 -6.17   8.911   1 72.328  ? 101 ILE A HB   1 c 
ATOM   1529 H HG12 . ILE A 1 101 ? -24.04  -6.311  8.988   1 72.325  ? 101 ILE A HG12 1 c 
ATOM   1530 H HG13 . ILE A 1 101 ? -23.289 -7.684  8.784   1 72.36   ? 101 ILE A HG13 1 c 
ATOM   1531 H HG21 . ILE A 1 101 ? -21.394 -8.096  10.455  1 73.78   ? 101 ILE A HG21 1 c 
ATOM   1532 H HG22 . ILE A 1 101 ? -21.5   -7.003  11.599  1 73.778  ? 101 ILE A HG22 1 c 
ATOM   1533 H HG23 . ILE A 1 101 ? -20.315 -6.94   10.545  1 73.793  ? 101 ILE A HG23 1 c 
ATOM   1534 H HD11 . ILE A 1 101 ? -23.721 -8.317  10.967  1 72.802  ? 101 ILE A HD11 1 c 
ATOM   1535 H HD12 . ILE A 1 101 ? -25.092 -7.819  10.336  1 72.876  ? 101 ILE A HD12 1 c 
ATOM   1536 H HD13 . ILE A 1 101 ? -24.28  -6.869  11.321  1 72.787  ? 101 ILE A HD13 1 c 
ATOM   1537 N N    . LYS A 1 102 ? -20.285 -3.551  10.047  1 72.795  ? 102 LYS A N    1 ? 
ATOM   1538 C CA   . LYS A 1 102 ? -19.078 -2.862  10.484  1 77.595  ? 102 LYS A CA   1 ? 
ATOM   1539 C C    . LYS A 1 102 ? -19.397 -1.942  11.666  1 86.85   ? 102 LYS A C    1 ? 
ATOM   1540 O O    . LYS A 1 102 ? -18.78  -2.076  12.722  1 88.59   ? 102 LYS A O    1 ? 
ATOM   1541 C CB   . LYS A 1 102 ? -18.4   -2.102  9.336   1 73.596  ? 102 LYS A CB   1 ? 
ATOM   1542 C CG   . LYS A 1 102 ? -17.129 -1.353  9.729   1 80.676  ? 102 LYS A CG   1 ? 
ATOM   1543 C CD   . LYS A 1 102 ? -16.004 -1.346  8.695   1 84.066  ? 102 LYS A CD   1 ? 
ATOM   1544 C CE   . LYS A 1 102 ? -16.388 -0.769  7.369   1 83.975  ? 102 LYS A CE   1 ? 
ATOM   1545 N NZ   . LYS A 1 102 ? -15.325 -0.864  6.366   1 82.758  ? 102 LYS A NZ   1 ? 
ATOM   1546 H H    . LYS A 1 102 ? -20.504 -3.525  9.16    1 73.871  ? 102 LYS A H    1 c 
ATOM   1547 H HA   . LYS A 1 102 ? -18.439 -3.549  10.8    1 77.473  ? 102 LYS A HA   1 c 
ATOM   1548 H HB2  . LYS A 1 102 ? -18.178 -2.738  8.624   1 76.071  ? 102 LYS A HB2  1 c 
ATOM   1549 H HB3  . LYS A 1 102 ? -19.036 -1.455  8.967   1 76.076  ? 102 LYS A HB3  1 c 
ATOM   1550 H HG2  . LYS A 1 102 ? -17.373 -0.424  9.931   1 79.745  ? 102 LYS A HG2  1 c 
ATOM   1551 H HG3  . LYS A 1 102 ? -16.783 -1.749  10.558  1 79.763  ? 102 LYS A HG3  1 c 
ATOM   1552 H HD2  . LYS A 1 102 ? -15.25  -0.832  9.057   1 83.26   ? 102 LYS A HD2  1 c 
ATOM   1553 H HD3  . LYS A 1 102 ? -15.695 -2.268  8.562   1 83.235  ? 102 LYS A HD3  1 c 
ATOM   1554 H HE2  . LYS A 1 102 ? -17.173 -1.234  7.028   1 83.736  ? 102 LYS A HE2  1 c 
ATOM   1555 H HE3  . LYS A 1 102 ? -16.625 0.169   7.486   1 83.712  ? 102 LYS A HE3  1 c 
ATOM   1556 H HZ1  . LYS A 1 102 ? -15.078 -1.73   6.263   1 83.105  ? 102 LYS A HZ1  1 c 
ATOM   1557 H HZ2  . LYS A 1 102 ? -14.607 -0.38   6.634   1 83.125  ? 102 LYS A HZ2  1 c 
ATOM   1558 H HZ3  . LYS A 1 102 ? -15.622 -0.542  5.573   1 83.125  ? 102 LYS A HZ3  1 c 
ATOM   1559 N N    . LYS A 1 103 ? -20.384 -1.048  11.49   1 93.378  ? 103 LYS A N    1 ? 
ATOM   1560 C CA   . LYS A 1 103 ? -20.755 -0.061  12.501  1 94.311  ? 103 LYS A CA   1 ? 
ATOM   1561 C C    . LYS A 1 103 ? -21.327 -0.743  13.747  1 88.038  ? 103 LYS A C    1 ? 
ATOM   1562 O O    . LYS A 1 103 ? -21.079 -0.268  14.85   1 94.093  ? 103 LYS A O    1 ? 
ATOM   1563 C CB   . LYS A 1 103 ? -21.723 1       11.955  1 95.552  ? 103 LYS A CB   1 ? 
ATOM   1564 C CG   . LYS A 1 103 ? -21.112 1.971   10.939  1 99.821  ? 103 LYS A CG   1 ? 
ATOM   1565 C CD   . LYS A 1 103 ? -22.1   2.949   10.299  1 102.481 ? 103 LYS A CD   1 ? 
ATOM   1566 C CE   . LYS A 1 103 ? -21.516 3.805   9.205   1 88.509  ? 103 LYS A CE   1 ? 
ATOM   1567 H H    . LYS A 1 103 ? -20.844 -1.05   10.7    1 91.77   ? 103 LYS A H    1 c 
ATOM   1568 H HA   . LYS A 1 103 ? -19.927 0.412   12.772  1 93.17   ? 103 LYS A HA   1 c 
ATOM   1569 H HB2  . LYS A 1 103 ? -22.481 0.544   11.53   1 96.214  ? 103 LYS A HB2  1 c 
ATOM   1570 H HB3  . LYS A 1 103 ? -22.075 1.522   12.708  1 96.177  ? 103 LYS A HB3  1 c 
ATOM   1571 H HG2  . LYS A 1 103 ? -20.407 2.485   11.391  1 99.356  ? 103 LYS A HG2  1 c 
ATOM   1572 H HG3  . LYS A 1 103 ? -20.683 1.443   10.231  1 99.353  ? 103 LYS A HG3  1 c 
ATOM   1573 H HD2  . LYS A 1 103 ? -22.852 2.436   9.931   1 98.484  ? 103 LYS A HD2  1 c 
ATOM   1574 H HD3  . LYS A 1 103 ? -22.459 3.534   11.001  1 98.484  ? 103 LYS A HD3  1 c 
ATOM   1575 N N    . LYS A 1 104 ? -22.062 -1.852  13.57   1 79.06   ? 104 LYS A N    1 ? 
ATOM   1576 C CA   . LYS A 1 104 ? -22.625 -2.609  14.68   1 78.178  ? 104 LYS A CA   1 ? 
ATOM   1577 C C    . LYS A 1 104 ? -21.547 -3.361  15.468  1 87.216  ? 104 LYS A C    1 ? 
ATOM   1578 O O    . LYS A 1 104 ? -21.623 -3.41   16.699  1 89.629  ? 104 LYS A O    1 ? 
ATOM   1579 C CB   . LYS A 1 104 ? -23.681 -3.609  14.193  1 77.797  ? 104 LYS A CB   1 ? 
ATOM   1580 C CG   . LYS A 1 104 ? -24.114 -4.645  15.225  1 72.622  ? 104 LYS A CG   1 ? 
ATOM   1581 C CD   . LYS A 1 104 ? -25.271 -5.527  14.773  1 75.093  ? 104 LYS A CD   1 ? 
ATOM   1582 C CE   . LYS A 1 104 ? -25.877 -6.264  15.924  1 79.992  ? 104 LYS A CE   1 ? 
ATOM   1583 N NZ   . LYS A 1 104 ? -26.732 -7.375  15.5    1 80.649  ? 104 LYS A NZ   1 ? 
ATOM   1584 H H    . LYS A 1 104 ? -22.232 -2.14   12.72   1 81.015  ? 104 LYS A H    1 c 
ATOM   1585 H HA   . LYS A 1 104 ? -23.072 -1.971  15.294  1 79.963  ? 104 LYS A HA   1 c 
ATOM   1586 H HB2  . LYS A 1 104 ? -24.475 -3.11   13.904  1 76.671  ? 104 LYS A HB2  1 c 
ATOM   1587 H HB3  . LYS A 1 104 ? -23.327 -4.083  13.411  1 76.693  ? 104 LYS A HB3  1 c 
ATOM   1588 H HG2  . LYS A 1 104 ? -23.349 -5.222  15.434  1 74.406  ? 104 LYS A HG2  1 c 
ATOM   1589 H HG3  . LYS A 1 104 ? -24.372 -4.177  16.049  1 74.378  ? 104 LYS A HG3  1 c 
ATOM   1590 H HD2  . LYS A 1 104 ? -25.958 -4.968  14.349  1 75.626  ? 104 LYS A HD2  1 c 
ATOM   1591 H HD3  . LYS A 1 104 ? -24.946 -6.174  14.11   1 75.626  ? 104 LYS A HD3  1 c 
ATOM   1592 H HE2  . LYS A 1 104 ? -25.168 -6.615  16.492  1 78.959  ? 104 LYS A HE2  1 c 
ATOM   1593 H HE3  . LYS A 1 104 ? -26.409 -5.645  16.457  1 78.988  ? 104 LYS A HE3  1 c 
ATOM   1594 H HZ1  . LYS A 1 104 ? -26.231 -8.005  15.084  1 80.446  ? 104 LYS A HZ1  1 c 
ATOM   1595 H HZ2  . LYS A 1 104 ? -27.365 -7.072  14.927  1 80.446  ? 104 LYS A HZ2  1 c 
ATOM   1596 H HZ3  . LYS A 1 104 ? -27.135 -7.744  16.222  1 80.446  ? 104 LYS A HZ3  1 c 
ATOM   1597 N N    . ASP A 1 105 ? -20.594 -4.004  14.769  1 78.961  ? 105 ASP A N    1 ? 
ATOM   1598 C CA   . ASP A 1 105 ? -19.67  -4.935  15.406  1 79.083  ? 105 ASP A CA   1 ? 
ATOM   1599 C C    . ASP A 1 105 ? -18.452 -5.193  14.518  1 77.954  ? 105 ASP A C    1 ? 
ATOM   1600 O O    . ASP A 1 105 ? -18.376 -6.228  13.85   1 77.931  ? 105 ASP A O    1 ? 
ATOM   1601 C CB   . ASP A 1 105 ? -20.369 -6.233  15.794  1 79.536  ? 105 ASP A CB   1 ? 
ATOM   1602 C CG   . ASP A 1 105 ? -19.5   -7.265  16.498  1 80.164  ? 105 ASP A CG   1 ? 
ATOM   1603 O OD1  . ASP A 1 105 ? -18.275 -7.019  16.629  1 81.705  ? 105 ASP A OD1  1 ? 
ATOM   1604 O OD2  . ASP A 1 105 ? -20.056 -8.306  16.91   1 78.253  ? 105 ASP A OD2  1 ? 
ATOM   1605 H H    . ASP A 1 105 ? -20.525 -3.864  13.868  1 80.836  ? 105 ASP A H    1 c 
ATOM   1606 H HA   . ASP A 1 105 ? -19.355 -4.528  16.245  1 79.055  ? 105 ASP A HA   1 c 
ATOM   1607 H HB2  . ASP A 1 105 ? -21.117 -6.025  16.392  1 79.657  ? 105 ASP A HB2  1 c 
ATOM   1608 H HB3  . ASP A 1 105 ? -20.741 -6.646  14.987  1 79.584  ? 105 ASP A HB3  1 c 
ATOM   1609 N N    . VAL A 1 106 ? -17.454 -4.304  14.624  1 82.11   ? 106 VAL A N    1 ? 
ATOM   1610 C CA   . VAL A 1 106 ? -16.27  -4.311  13.768  1 88.102  ? 106 VAL A CA   1 ? 
ATOM   1611 C C    . VAL A 1 106 ? -15.622 -5.704  13.79   1 85.053  ? 106 VAL A C    1 ? 
ATOM   1612 O O    . VAL A 1 106 ? -15.139 -6.16   12.752  1 84.749  ? 106 VAL A O    1 ? 
ATOM   1613 C CB   . VAL A 1 106 ? -15.231 -3.21   14.109  1 97.796  ? 106 VAL A CB   1 ? 
ATOM   1614 C CG1  . VAL A 1 106 ? -14.147 -3.085  13.037  1 94.237  ? 106 VAL A CG1  1 ? 
ATOM   1615 C CG2  . VAL A 1 106 ? -15.853 -1.831  14.344  1 106.208 ? 106 VAL A CG2  1 ? 
ATOM   1616 H H    . VAL A 1 106 ? -17.507 -3.676  15.285  1 82.647  ? 106 VAL A H    1 c 
ATOM   1617 H HA   . VAL A 1 106 ? -16.577 -4.148  12.855  1 88.046  ? 106 VAL A HA   1 c 
ATOM   1618 H HB   . VAL A 1 106 ? -14.788 -3.482  14.947  1 96.685  ? 106 VAL A HB   1 c 
ATOM   1619 H HG11 . VAL A 1 106 ? -14.554 -3.138  12.155  1 95.201  ? 106 VAL A HG11 1 c 
ATOM   1620 H HG12 . VAL A 1 106 ? -13.507 -3.807  13.14   1 95.098  ? 106 VAL A HG12 1 c 
ATOM   1621 H HG13 . VAL A 1 106 ? -13.688 -2.234  13.129  1 95.333  ? 106 VAL A HG13 1 c 
ATOM   1622 H HG21 . VAL A 1 106 ? -15.149 -1.172  14.462  1 103.446 ? 106 VAL A HG21 1 c 
ATOM   1623 H HG22 . VAL A 1 106 ? -16.406 -1.851  15.142  1 103.293 ? 106 VAL A HG22 1 c 
ATOM   1624 H HG23 . VAL A 1 106 ? -16.398 -1.586  13.579  1 103.466 ? 106 VAL A HG23 1 c 
ATOM   1625 N N    . LYS A 1 107 ? -15.606 -6.369  14.961  1 83.386  ? 107 LYS A N    1 ? 
ATOM   1626 C CA   . LYS A 1 107 ? -14.966 -7.671  15.114  1 85.786  ? 107 LYS A CA   1 ? 
ATOM   1627 C C    . LYS A 1 107 ? -15.65  -8.687  14.198  1 83.958  ? 107 LYS A C    1 ? 
ATOM   1628 O O    . LYS A 1 107 ? -14.972 -9.431  13.497  1 84.383  ? 107 LYS A O    1 ? 
ATOM   1629 C CB   . LYS A 1 107 ? -14.932 -8.192  16.559  1 75.538  ? 107 LYS A CB   1 ? 
ATOM   1630 H H    . LYS A 1 107 ? -15.989 -5.984  15.697  1 84.232  ? 107 LYS A H    1 c 
ATOM   1631 H HA   . LYS A 1 107 ? -14.026 -7.578  14.813  1 83.022  ? 107 LYS A HA   1 c 
ATOM   1632 N N    . LEU A 1 108 ? -16.986 -8.694  14.193  1 77.674  ? 108 LEU A N    1 ? 
ATOM   1633 C CA   . LEU A 1 108 ? -17.746 -9.627  13.375  1 75.316  ? 108 LEU A CA   1 ? 
ATOM   1634 C C    . LEU A 1 108 ? -17.529 -9.336  11.886  1 68.713  ? 108 LEU A C    1 ? 
ATOM   1635 O O    . LEU A 1 108 ? -17.39  -10.265 11.096  1 65.803  ? 108 LEU A O    1 ? 
ATOM   1636 C CB   . LEU A 1 108 ? -19.225 -9.584  13.759  1 70.879  ? 108 LEU A CB   1 ? 
ATOM   1637 C CG   . LEU A 1 108 ? -20.14  -10.571 13.024  1 71.916  ? 108 LEU A CG   1 ? 
ATOM   1638 C CD1  . LEU A 1 108 ? -19.535 -11.973 12.956  1 69.728  ? 108 LEU A CD1  1 ? 
ATOM   1639 C CD2  . LEU A 1 108 ? -21.519 -10.62  13.67   1 66.494  ? 108 LEU A CD2  1 ? 
ATOM   1640 H H    . LEU A 1 108 ? -17.441 -8.102  14.72   1 78.596  ? 108 LEU A H    1 c 
ATOM   1641 H HA   . LEU A 1 108 ? -17.396 -10.535 13.56   1 73.744  ? 108 LEU A HA   1 c 
ATOM   1642 H HB2  . LEU A 1 108 ? -19.296 -9.756  14.726  1 72.105  ? 108 LEU A HB2  1 c 
ATOM   1643 H HB3  . LEU A 1 108 ? -19.558 -8.671  13.594  1 72.105  ? 108 LEU A HB3  1 c 
ATOM   1644 H HG   . LEU A 1 108 ? -20.256 -10.247 12.094  1 70.27   ? 108 LEU A HG   1 c 
ATOM   1645 H HD11 . LEU A 1 108 ? -18.87  -12.009 12.251  1 70.315  ? 108 LEU A HD11 1 c 
ATOM   1646 H HD12 . LEU A 1 108 ? -20.235 -12.621 12.772  1 70.333  ? 108 LEU A HD12 1 c 
ATOM   1647 H HD13 . LEU A 1 108 ? -19.114 -12.186 13.806  1 70.369  ? 108 LEU A HD13 1 c 
ATOM   1648 H HD21 . LEU A 1 108 ? -21.88  -9.72   13.735  1 68.047  ? 108 LEU A HD21 1 c 
ATOM   1649 H HD22 . LEU A 1 108 ? -21.448 -11.003 14.561  1 68.047  ? 108 LEU A HD22 1 c 
ATOM   1650 H HD23 . LEU A 1 108 ? -22.113 -11.168 13.13   1 68.048  ? 108 LEU A HD23 1 c 
ATOM   1651 N N    . TYR A 1 109 ? -17.45  -8.049  11.527  1 59.237  ? 109 TYR A N    1 ? 
ATOM   1652 C CA   . TYR A 1 109 ? -17.215 -7.627  10.157  1 66.779  ? 109 TYR A CA   1 ? 
ATOM   1653 C C    . TYR A 1 109 ? -15.915 -8.234  9.634   1 68.557  ? 109 TYR A C    1 ? 
ATOM   1654 O O    . TYR A 1 109 ? -15.901 -8.763  8.524   1 68.645  ? 109 TYR A O    1 ? 
ATOM   1655 C CB   . TYR A 1 109 ? -17.225 -6.098  10.033  1 67.156  ? 109 TYR A CB   1 ? 
ATOM   1656 C CG   . TYR A 1 109 ? -16.825 -5.539  8.671   1 69.331  ? 109 TYR A CG   1 ? 
ATOM   1657 C CD1  . TYR A 1 109 ? -15.505 -5.193  8.393   1 70.65   ? 109 TYR A CD1  1 ? 
ATOM   1658 C CD2  . TYR A 1 109 ? -17.767 -5.339  7.666   1 68.796  ? 109 TYR A CD2  1 ? 
ATOM   1659 C CE1  . TYR A 1 109 ? -15.131 -4.681  7.158   1 76.85   ? 109 TYR A CE1  1 ? 
ATOM   1660 C CE2  . TYR A 1 109 ? -17.402 -4.837  6.424   1 73.998  ? 109 TYR A CE2  1 ? 
ATOM   1661 C CZ   . TYR A 1 109 ? -16.084 -4.49   6.169   1 77.442  ? 109 TYR A CZ   1 ? 
ATOM   1662 O OH   . TYR A 1 109 ? -15.727 -3.991  4.938   1 79.118  ? 109 TYR A OH   1 ? 
ATOM   1663 H H    . TYR A 1 109 ? -17.564 -7.403  12.164  1 63.25   ? 109 TYR A H    1 c 
ATOM   1664 H HA   . TYR A 1 109 ? -17.96  -7.98   9.602   1 65.635  ? 109 TYR A HA   1 c 
ATOM   1665 H HB2  . TYR A 1 109 ? -18.13  -5.782  10.245  1 67.64   ? 109 TYR A HB2  1 c 
ATOM   1666 H HB3  . TYR A 1 109 ? -16.62  -5.729  10.711  1 67.66   ? 109 TYR A HB3  1 c 
ATOM   1667 H HD1  . TYR A 1 109 ? -14.846 -5.313  9.059   1 71.765  ? 109 TYR A HD1  1 c 
ATOM   1668 H HD2  . TYR A 1 109 ? -18.668 -5.568  7.825   1 70.157  ? 109 TYR A HD2  1 c 
ATOM   1669 H HE1  . TYR A 1 109 ? -14.231 -4.456  6.993   1 75.407  ? 109 TYR A HE1  1 c 
ATOM   1670 H HE2  . TYR A 1 109 ? -18.053 -4.707  5.76    1 73.449  ? 109 TYR A HE2  1 c 
ATOM   1671 N N    . ASN A 1 110 ? -14.838 -8.168  10.429  1 69.834  ? 110 ASN A N    1 ? 
ATOM   1672 C CA   . ASN A 1 110 ? -13.534 -8.641  9.974   1 69.134  ? 110 ASN A CA   1 ? 
ATOM   1673 C C    . ASN A 1 110 ? -13.533 -10.168 9.854   1 64.665  ? 110 ASN A C    1 ? 
ATOM   1674 O O    . ASN A 1 110 ? -12.77  -10.699 9.055   1 70.86   ? 110 ASN A O    1 ? 
ATOM   1675 C CB   . ASN A 1 110 ? -12.397 -8.089  10.83   1 75.268  ? 110 ASN A CB   1 ? 
ATOM   1676 C CG   . ASN A 1 110 ? -12.192 -6.607  10.612  1 85.999  ? 110 ASN A CG   1 ? 
ATOM   1677 O OD1  . ASN A 1 110 ? -11.642 -6.193  9.584   1 91.472  ? 110 ASN A OD1  1 ? 
ATOM   1678 N ND2  . ASN A 1 110 ? -12.628 -5.793  11.561  1 88.646  ? 110 ASN A ND2  1 ? 
ATOM   1679 H H    . ASN A 1 110 ? -14.911 -7.815  11.268  1 69.318  ? 110 ASN A H    1 c 
ATOM   1680 H HA   . ASN A 1 110 ? -13.396 -8.283  9.066   1 69.583  ? 110 ASN A HA   1 c 
ATOM   1681 H HB2  . ASN A 1 110 ? -12.597 -8.251  11.774  1 76.187  ? 110 ASN A HB2  1 c 
ATOM   1682 H HB3  . ASN A 1 110 ? -11.57  -8.563  10.61   1 76.078  ? 110 ASN A HB3  1 c 
ATOM   1683 H HD21 . ASN A 1 110 ? -12.048 -5.321  12.038  1 87.892  ? 110 ASN A HD21 1 c 
ATOM   1684 H HD22 . ASN A 1 110 ? -13.498 -5.722  11.718  1 87.892  ? 110 ASN A HD22 1 c 
ATOM   1685 N N    . ASP A 1 111 ? -14.43  -10.849 10.591  1 63.574  ? 111 ASP A N    1 ? 
ATOM   1686 C CA   . ASP A 1 111 ? -14.571 -12.302 10.585  1 70.233  ? 111 ASP A CA   1 ? 
ATOM   1687 C C    . ASP A 1 111 ? -15.418 -12.846 9.417   1 73.956  ? 111 ASP A C    1 ? 
ATOM   1688 O O    . ASP A 1 111 ? -15.459 -14.067 9.241   1 69.273  ? 111 ASP A O    1 ? 
ATOM   1689 C CB   . ASP A 1 111 ? -15.182 -12.787 11.897  1 76.817  ? 111 ASP A CB   1 ? 
ATOM   1690 C CG   . ASP A 1 111 ? -14.29  -12.847 13.14   1 84.761  ? 111 ASP A CG   1 ? 
ATOM   1691 O OD1  . ASP A 1 111 ? -13.059 -12.606 13.038  1 81.932  ? 111 ASP A OD1  1 ? 
ATOM   1692 O OD2  . ASP A 1 111 ? -14.84  -13.148 14.228  1 75.558  ? 111 ASP A OD2  1 ? 
ATOM   1693 H H    . ASP A 1 111 ? -14.966 -10.379 11.161  1 65.541  ? 111 ASP A H    1 c 
ATOM   1694 H HA   . ASP A 1 111 ? -13.672 -12.696 10.517  1 70.722  ? 111 ASP A HA   1 c 
ATOM   1695 H HB2  . ASP A 1 111 ? -15.947 -12.217 12.116  1 76.835  ? 111 ASP A HB2  1 c 
ATOM   1696 H HB3  . ASP A 1 111 ? -15.532 -13.694 11.771  1 76.927  ? 111 ASP A HB3  1 c 
ATOM   1697 N N    . ILE A 1 112 ? -16.134 -11.982 8.661   1 69.853  ? 112 ILE A N    1 ? 
ATOM   1698 C CA   . ILE A 1 112 ? -17.036 -12.43  7.598   1 66.258  ? 112 ILE A CA   1 ? 
ATOM   1699 C C    . ILE A 1 112 ? -16.756 -11.775 6.247   1 56.026  ? 112 ILE A C    1 ? 
ATOM   1700 O O    . ILE A 1 112 ? -17.331 -12.202 5.259   1 59.529  ? 112 ILE A O    1 ? 
ATOM   1701 C CB   . ILE A 1 112 ? -18.518 -12.212 7.964   1 64.674  ? 112 ILE A CB   1 ? 
ATOM   1702 C CG1  . ILE A 1 112 ? -18.909 -10.721 7.955   1 64.109  ? 112 ILE A CG1  1 ? 
ATOM   1703 C CG2  . ILE A 1 112 ? -18.854 -12.9   9.288   1 64.631  ? 112 ILE A CG2  1 ? 
ATOM   1704 C CD1  . ILE A 1 112 ? -20.379 -10.464 8.241   1 66.248  ? 112 ILE A CD1  1 ? 
ATOM   1705 H H    . ILE A 1 112 ? -16.094 -11.089 8.848   1 69.698  ? 112 ILE A H    1 c 
ATOM   1706 H HA   . ILE A 1 112 ? -16.909 -13.391 7.483   1 64.665  ? 112 ILE A HA   1 c 
ATOM   1707 H HB   . ILE A 1 112 ? -19.051 -12.649 7.27    1 64.824  ? 112 ILE A HB   1 c 
ATOM   1708 H HG12 . ILE A 1 112 ? -18.372 -10.252 8.625   1 64.718  ? 112 ILE A HG12 1 c 
ATOM   1709 H HG13 . ILE A 1 112 ? -18.696 -10.339 7.08    1 64.672  ? 112 ILE A HG13 1 c 
ATOM   1710 H HG21 . ILE A 1 112 ? -19.818 -12.923 9.413   1 64.691  ? 112 ILE A HG21 1 c 
ATOM   1711 H HG22 . ILE A 1 112 ? -18.448 -12.411 10.02   1 64.728  ? 112 ILE A HG22 1 c 
ATOM   1712 H HG23 . ILE A 1 112 ? -18.509 -13.809 9.28    1 64.695  ? 112 ILE A HG23 1 c 
ATOM   1713 H HD11 . ILE A 1 112 ? -20.924 -11.111 7.756   1 65.609  ? 112 ILE A HD11 1 c 
ATOM   1714 H HD12 . ILE A 1 112 ? -20.614 -9.562  7.952   1 65.609  ? 112 ILE A HD12 1 c 
ATOM   1715 H HD13 . ILE A 1 112 ? -20.546 -10.551 9.198   1 65.605  ? 112 ILE A HD13 1 c 
ATOM   1716 N N    . VAL A 1 113 ? -15.942 -10.723 6.18    1 57.803  ? 113 VAL A N    1 ? 
ATOM   1717 C CA   . VAL A 1 113 ? -15.729 -10.044 4.916   1 60.128  ? 113 VAL A CA   1 ? 
ATOM   1718 C C    . VAL A 1 113 ? -14.539 -10.722 4.237   1 67.425  ? 113 VAL A C    1 ? 
ATOM   1719 O O    . VAL A 1 113 ? -13.622 -11.169 4.914   1 76.835  ? 113 VAL A O    1 ? 
ATOM   1720 C CB   . VAL A 1 113 ? -15.53  -8.524  5.097   1 68.202  ? 113 VAL A CB   1 ? 
ATOM   1721 C CG1  . VAL A 1 113 ? -14.192 -8.174  5.747   1 70.916  ? 113 VAL A CG1  1 ? 
ATOM   1722 C CG2  . VAL A 1 113 ? -15.681 -7.761  3.78    1 73.095  ? 113 VAL A CG2  1 ? 
ATOM   1723 H H    . VAL A 1 113 ? -15.507 -10.421 6.923   1 58.222  ? 113 VAL A H    1 c 
ATOM   1724 H HA   . VAL A 1 113 ? -16.518 -10.174 4.355   1 62.335  ? 113 VAL A HA   1 c 
ATOM   1725 H HB   . VAL A 1 113 ? -16.242 -8.212  5.703   1 67.983  ? 113 VAL A HB   1 c 
ATOM   1726 H HG11 . VAL A 1 113 ? -13.501 -8.127  5.065   1 70.08   ? 113 VAL A HG11 1 c 
ATOM   1727 H HG12 . VAL A 1 113 ? -13.955 -8.853  6.399   1 69.932  ? 113 VAL A HG12 1 c 
ATOM   1728 H HG13 . VAL A 1 113 ? -14.264 -7.312  6.191   1 70.068  ? 113 VAL A HG13 1 c 
ATOM   1729 H HG21 . VAL A 1 113 ? -15.648 -6.805  3.952   1 71.608  ? 113 VAL A HG21 1 c 
ATOM   1730 H HG22 . VAL A 1 113 ? -16.534 -7.985  3.37    1 71.603  ? 113 VAL A HG22 1 c 
ATOM   1731 H HG23 . VAL A 1 113 ? -14.959 -8.006  3.177   1 71.562  ? 113 VAL A HG23 1 c 
ATOM   1732 N N    . THR A 1 114 ? -14.558 -10.809 2.903   1 65.376  ? 114 THR A N    1 ? 
ATOM   1733 C CA   . THR A 1 114 ? -13.406 -11.31  2.177   1 65.431  ? 114 THR A CA   1 ? 
ATOM   1734 C C    . THR A 1 114 ? -12.254 -10.342 2.439   1 72.395  ? 114 THR A C    1 ? 
ATOM   1735 O O    . THR A 1 114 ? -12.476 -9.164  2.715   1 74.091  ? 114 THR A O    1 ? 
ATOM   1736 C CB   . THR A 1 114 ? -13.678 -11.455 0.676   1 66.463  ? 114 THR A CB   1 ? 
ATOM   1737 O OG1  . THR A 1 114 ? -13.827 -10.158 0.106   1 62.395  ? 114 THR A OG1  1 ? 
ATOM   1738 C CG2  . THR A 1 114 ? -14.891 -12.317 0.366   1 66.315  ? 114 THR A CG2  1 ? 
ATOM   1739 H H    . THR A 1 114 ? -15.289 -10.517 2.438   1 65.813  ? 114 THR A H    1 c 
ATOM   1740 H HA   . THR A 1 114 ? -13.171 -12.192 2.539   1 66.918  ? 114 THR A HA   1 c 
ATOM   1741 H HB   . THR A 1 114 ? -12.891 -11.889 0.269   1 65.434  ? 114 THR A HB   1 c 
ATOM   1742 H HG21 . THR A 1 114 ? -15.302 -12.015 -0.461  1 66.192  ? 114 THR A HG21 1 c 
ATOM   1743 H HG22 . THR A 1 114 ? -15.538 -12.258 1.086   1 66.294  ? 114 THR A HG22 1 c 
ATOM   1744 H HG23 . THR A 1 114 ? -14.611 -13.241 0.265   1 66.239  ? 114 THR A HG23 1 c 
ATOM   1745 N N    . ASP A 1 115 ? -11.027 -10.855 2.346   1 70.401  ? 115 ASP A N    1 ? 
ATOM   1746 C CA   . ASP A 1 115 ? -9.838  -10.049 2.568   1 76.642  ? 115 ASP A CA   1 ? 
ATOM   1747 C C    . ASP A 1 115 ? -9.624  -9.081  1.404   1 74.449  ? 115 ASP A C    1 ? 
ATOM   1748 O O    . ASP A 1 115 ? -8.907  -8.1    1.575   1 77.74   ? 115 ASP A O    1 ? 
ATOM   1749 C CB   . ASP A 1 115 ? -8.616  -10.908 2.875   1 77.091  ? 115 ASP A CB   1 ? 
ATOM   1750 C CG   . ASP A 1 115 ? -8.329  -12.046 1.904   1 81.81   ? 115 ASP A CG   1 ? 
ATOM   1751 O OD1  . ASP A 1 115 ? -9.062  -13.05  1.951   1 91.222  ? 115 ASP A OD1  1 ? 
ATOM   1752 O OD2  . ASP A 1 115 ? -7.389  -11.918 1.098   1 83.764  ? 115 ASP A OD2  1 ? 
ATOM   1753 H H    . ASP A 1 115 ? -10.93  -11.74  2.137   1 72.234  ? 115 ASP A H    1 c 
ATOM   1754 H HA   . ASP A 1 115 ? -9.987  -9.512  3.38    1 75.058  ? 115 ASP A HA   1 c 
ATOM   1755 H HB2  . ASP A 1 115 ? -7.828  -10.326 2.9     1 78.06   ? 115 ASP A HB2  1 c 
ATOM   1756 H HB3  . ASP A 1 115 ? -8.728  -11.296 3.768   1 78.049  ? 115 ASP A HB3  1 c 
ATOM   1757 N N    . TYR A 1 116 ? -10.262 -9.33   0.247   1 70.163  ? 116 TYR A N    1 ? 
ATOM   1758 C CA   . TYR A 1 116 ? -9.984  -8.589  -0.981  1 68.255  ? 116 TYR A CA   1 ? 
ATOM   1759 C C    . TYR A 1 116 ? -11.135 -7.658  -1.386  1 67.876  ? 116 TYR A C    1 ? 
ATOM   1760 O O    . TYR A 1 116 ? -10.884 -6.679  -2.092  1 69.996  ? 116 TYR A O    1 ? 
ATOM   1761 C CB   . TYR A 1 116 ? -9.65   -9.554  -2.13   1 63.403  ? 116 TYR A CB   1 ? 
ATOM   1762 C CG   . TYR A 1 116 ? -10.788 -10.487 -2.513  1 71.464  ? 116 TYR A CG   1 ? 
ATOM   1763 C CD1  . TYR A 1 116 ? -11.737 -10.104 -3.455  1 70.102  ? 116 TYR A CD1  1 ? 
ATOM   1764 C CD2  . TYR A 1 116 ? -10.941 -11.735 -1.905  1 69.018  ? 116 TYR A CD2  1 ? 
ATOM   1765 C CE1  . TYR A 1 116 ? -12.792 -10.934 -3.787  1 70.856  ? 116 TYR A CE1  1 ? 
ATOM   1766 C CE2  . TYR A 1 116 ? -11.991 -12.579 -2.238  1 64.693  ? 116 TYR A CE2  1 ? 
ATOM   1767 C CZ   . TYR A 1 116 ? -12.92  -12.173 -3.183  1 68.609  ? 116 TYR A CZ   1 ? 
ATOM   1768 O OH   . TYR A 1 116 ? -13.968 -12.968 -3.529  1 66.043  ? 116 TYR A OH   1 ? 
ATOM   1769 H H    . TYR A 1 116 ? -10.877 -10.002 0.212   1 70.737  ? 116 TYR A H    1 c 
ATOM   1770 H HA   . TYR A 1 116 ? -9.182  -8.023  -0.827  1 67.724  ? 116 TYR A HA   1 c 
ATOM   1771 H HB2  . TYR A 1 116 ? -9.395  -9.024  -2.918  1 66.256  ? 116 TYR A HB2  1 c 
ATOM   1772 H HB3  . TYR A 1 116 ? -8.871  -10.094 -1.867  1 66.256  ? 116 TYR A HB3  1 c 
ATOM   1773 H HD1  . TYR A 1 116 ? -11.663 -9.26   -3.871  1 70.483  ? 116 TYR A HD1  1 c 
ATOM   1774 H HD2  . TYR A 1 116 ? -10.313 -12.015 -1.259  1 68.503  ? 116 TYR A HD2  1 c 
ATOM   1775 H HE1  . TYR A 1 116 ? -13.416 -10.658 -4.427  1 69.941  ? 116 TYR A HE1  1 c 
ATOM   1776 H HE2  . TYR A 1 116 ? -12.076 -13.419 -1.821  1 66.636  ? 116 TYR A HE2  1 c 
ATOM   1777 N N    . SER A 1 117 ? -12.388 -7.973  -1.016  1 69.114  ? 117 SER A N    1 ? 
ATOM   1778 C CA   . SER A 1 117 ? -13.532 -7.155  -1.421  1 67.114  ? 117 SER A CA   1 ? 
ATOM   1779 C C    . SER A 1 117 ? -14.413 -6.808  -0.224  1 61.983  ? 117 SER A C    1 ? 
ATOM   1780 O O    . SER A 1 117 ? -14.853 -7.709  0.491   1 66.139  ? 117 SER A O    1 ? 
ATOM   1781 C CB   . SER A 1 117 ? -14.365 -7.843  -2.488  1 68.835  ? 117 SER A CB   1 ? 
ATOM   1782 O OG   . SER A 1 117 ? -15.556 -7.124  -2.784  1 62.472  ? 117 SER A OG   1 ? 
ATOM   1783 H H    . SER A 1 117 ? -12.542 -8.717  -0.51   1 68.397  ? 117 SER A H    1 c 
ATOM   1784 H HA   . SER A 1 117 ? -13.19  -6.31   -1.803  1 66.824  ? 117 SER A HA   1 c 
ATOM   1785 H HB2  . SER A 1 117 ? -13.832 -7.931  -3.301  1 66.879  ? 117 SER A HB2  1 c 
ATOM   1786 H HB3  . SER A 1 117 ? -14.598 -8.74   -2.183  1 66.879  ? 117 SER A HB3  1 c 
ATOM   1787 N N    . GLU A 1 118 ? -14.741 -5.512  -0.098  1 62.802  ? 118 GLU A N    1 ? 
ATOM   1788 C CA   . GLU A 1 118 ? -15.672 -4.996  0.902   1 76.379  ? 118 GLU A CA   1 ? 
ATOM   1789 C C    . GLU A 1 118 ? -17.133 -5.203  0.485   1 65.403  ? 118 GLU A C    1 ? 
ATOM   1790 O O    . GLU A 1 118 ? -18.045 -5.009  1.292   1 58.406  ? 118 GLU A O    1 ? 
ATOM   1791 C CB   . GLU A 1 118 ? -15.445 -3.497  1.107   1 87.792  ? 118 GLU A CB   1 ? 
ATOM   1792 C CG   . GLU A 1 118 ? -14.031 -3.141  1.562   1 97.912  ? 118 GLU A CG   1 ? 
ATOM   1793 C CD   . GLU A 1 118 ? -13.659 -1.671  1.445   1 104.606 ? 118 GLU A CD   1 ? 
ATOM   1794 O OE1  . GLU A 1 118 ? -14.377 -0.9    0.767   1 104.661 ? 118 GLU A OE1  1 ? 
ATOM   1795 O OE2  . GLU A 1 118 ? -12.634 -1.297  2.055   1 104.489 ? 118 GLU A OE2  1 ? 
ATOM   1796 H H    . GLU A 1 118 ? -14.369 -4.914  -0.68   1 65.941  ? 118 GLU A H    1 c 
ATOM   1797 H HA   . GLU A 1 118 ? -15.511 -5.469  1.758   1 73.218  ? 118 GLU A HA   1 c 
ATOM   1798 H HB2  . GLU A 1 118 ? -15.64  -3.038  0.264   1 87.103  ? 118 GLU A HB2  1 c 
ATOM   1799 H HB3  . GLU A 1 118 ? -16.082 -3.172  1.777   1 87.047  ? 118 GLU A HB3  1 c 
ATOM   1800 H HG2  . GLU A 1 118 ? -13.925 -3.41   2.499   1 96.881  ? 118 GLU A HG2  1 c 
ATOM   1801 H HG3  . GLU A 1 118 ? -13.386 -3.66   1.038   1 96.489  ? 118 GLU A HG3  1 c 
ATOM   1802 N N    . GLU A 1 119 ? -17.352 -5.6    -0.773  1 66.006  ? 119 GLU A N    1 ? 
ATOM   1803 C CA   . GLU A 1 119 ? -18.687 -5.864  -1.287  1 67.549  ? 119 GLU A CA   1 ? 
ATOM   1804 C C    . GLU A 1 119 ? -19.047 -7.341  -1.166  1 62.745  ? 119 GLU A C    1 ? 
ATOM   1805 O O    . GLU A 1 119 ? -20.182 -7.694  -1.453  1 68.052  ? 119 GLU A O    1 ? 
ATOM   1806 C CB   . GLU A 1 119 ? -18.752 -5.524  -2.776  1 68.635  ? 119 GLU A CB   1 ? 
ATOM   1807 C CG   . GLU A 1 119 ? -18.359 -4.094  -3.135  1 70.942  ? 119 GLU A CG   1 ? 
ATOM   1808 C CD   . GLU A 1 119 ? -18.27  -3.922  -4.649  1 76.738  ? 119 GLU A CD   1 ? 
ATOM   1809 O OE1  . GLU A 1 119 ? -18.521 -4.901  -5.388  1 71.446  ? 119 GLU A OE1  1 ? 
ATOM   1810 O OE2  . GLU A 1 119 ? -17.949 -2.804  -5.111  1 77.368  ? 119 GLU A OE2  1 ? 
ATOM   1811 H H    . GLU A 1 119 ? -16.649 -5.685  -1.349  1 66.233  ? 119 GLU A H    1 c 
ATOM   1812 H HA   . GLU A 1 119 ? -19.347 -5.323  -0.788  1 66.511  ? 119 GLU A HA   1 c 
ATOM   1813 H HB2  . GLU A 1 119 ? -18.14  -6.128  -3.248  1 68.907  ? 119 GLU A HB2  1 c 
ATOM   1814 H HB3  . GLU A 1 119 ? -19.653 -5.707  -3.104  1 68.816  ? 119 GLU A HB3  1 c 
ATOM   1815 H HG2  . GLU A 1 119 ? -19.027 -3.47   -2.781  1 71.674  ? 119 GLU A HG2  1 c 
ATOM   1816 H HG3  . GLU A 1 119 ? -17.489 -3.878  -2.738  1 71.653  ? 119 GLU A HG3  1 c 
ATOM   1817 N N    . THR A 1 120 ? -18.093 -8.205  -0.781  1 62.698  ? 120 THR A N    1 ? 
ATOM   1818 C CA   . THR A 1 120 ? -18.305 -9.642  -0.874  1 60.89   ? 120 THR A CA   1 ? 
ATOM   1819 C C    . THR A 1 120 ? -18.156 -10.28  0.498   1 63.769  ? 120 THR A C    1 ? 
ATOM   1820 O O    . THR A 1 120 ? -17.117 -10.13  1.143   1 67.006  ? 120 THR A O    1 ? 
ATOM   1821 C CB   . THR A 1 120 ? -17.331 -10.276 -1.867  1 58.143  ? 120 THR A CB   1 ? 
ATOM   1822 O OG1  . THR A 1 120 ? -17.426 -9.476  -3.038  1 64.439  ? 120 THR A OG1  1 ? 
ATOM   1823 C CG2  . THR A 1 120 ? -17.712 -11.702 -2.209  1 56.197  ? 120 THR A CG2  1 ? 
ATOM   1824 H H    . THR A 1 120 ? -17.298 -7.9    -0.451  1 62.341  ? 120 THR A H    1 c 
ATOM   1825 H HA   . THR A 1 120 ? -19.211 -9.802  -1.2    1 61.049  ? 120 THR A HA   1 c 
ATOM   1826 H HB   . THR A 1 120 ? -16.41  -10.242 -1.514  1 59.496  ? 120 THR A HB   1 c 
ATOM   1827 H HG21 . THR A 1 120 ? -17.254 -11.974 -3.022  1 56.795  ? 120 THR A HG21 1 c 
ATOM   1828 H HG22 . THR A 1 120 ? -18.673 -11.76  -2.347  1 56.817  ? 120 THR A HG22 1 c 
ATOM   1829 H HG23 . THR A 1 120 ? -17.454 -12.292 -1.482  1 56.862  ? 120 THR A HG23 1 c 
ATOM   1830 N N    . LEU A 1 121 ? -19.203 -11.02  0.883   1 56.852  ? 121 LEU A N    1 ? 
ATOM   1831 C CA   . LEU A 1 121 ? -19.219 -11.855 2.067   1 57.437  ? 121 LEU A CA   1 ? 
ATOM   1832 C C    . LEU A 1 121 ? -18.384 -13.111 1.826   1 63.742  ? 121 LEU A C    1 ? 
ATOM   1833 O O    . LEU A 1 121 ? -18.489 -13.732 0.774   1 59.551  ? 121 LEU A O    1 ? 
ATOM   1834 C CB   . LEU A 1 121 ? -20.67  -12.227 2.357   1 57.923  ? 121 LEU A CB   1 ? 
ATOM   1835 C CG   . LEU A 1 121 ? -20.867 -13.217 3.503   1 62.574  ? 121 LEU A CG   1 ? 
ATOM   1836 C CD1  . LEU A 1 121 ? -20.666 -12.5   4.83    1 65.428  ? 121 LEU A CD1  1 ? 
ATOM   1837 C CD2  . LEU A 1 121 ? -22.213 -13.856 3.404   1 61.769  ? 121 LEU A CD2  1 ? 
ATOM   1838 H H    . LEU A 1 121 ? -19.959 -10.996 0.37    1 58.598  ? 121 LEU A H    1 c 
ATOM   1839 H HA   . LEU A 1 121 ? -18.845 -11.34  2.826   1 58.682  ? 121 LEU A HA   1 c 
ATOM   1840 H HB2  . LEU A 1 121 ? -21.165 -11.402 2.567   1 58.875  ? 121 LEU A HB2  1 c 
ATOM   1841 H HB3  . LEU A 1 121 ? -21.059 -12.617 1.54    1 58.859  ? 121 LEU A HB3  1 c 
ATOM   1842 H HG   . LEU A 1 121 ? -20.188 -13.933 3.431   1 62.086  ? 121 LEU A HG   1 c 
ATOM   1843 H HD11 . LEU A 1 121 ? -19.804 -12.057 4.835   1 64.486  ? 121 LEU A HD11 1 c 
ATOM   1844 H HD12 . LEU A 1 121 ? -20.703 -13.143 5.557   1 64.599  ? 121 LEU A HD12 1 c 
ATOM   1845 H HD13 . LEU A 1 121 ? -21.366 -11.838 4.95    1 64.621  ? 121 LEU A HD13 1 c 
ATOM   1846 H HD21 . LEU A 1 121 ? -22.207 -14.518 2.693   1 62.026  ? 121 LEU A HD21 1 c 
ATOM   1847 H HD22 . LEU A 1 121 ? -22.881 -13.177 3.208   1 62.062  ? 121 LEU A HD22 1 c 
ATOM   1848 H HD23 . LEU A 1 121 ? -22.43  -14.289 4.247   1 62.04   ? 121 LEU A HD23 1 c 
ATOM   1849 N N    . ASP A 1 122 ? -17.634 -13.526 2.856   1 66.596  ? 122 ASP A N    1 ? 
ATOM   1850 C CA   . ASP A 1 122 ? -16.718 -14.654 2.767   1 59.846  ? 122 ASP A CA   1 ? 
ATOM   1851 C C    . ASP A 1 122 ? -17.533 -15.944 2.669   1 51.192  ? 122 ASP A C    1 ? 
ATOM   1852 O O    . ASP A 1 122 ? -17.896 -16.577 3.66    1 45.067  ? 122 ASP A O    1 ? 
ATOM   1853 C CB   . ASP A 1 122 ? -15.668 -14.55  3.863   1 67.005  ? 122 ASP A CB   1 ? 
ATOM   1854 C CG   . ASP A 1 122 ? -14.615 -15.645 3.916   1 66.704  ? 122 ASP A CG   1 ? 
ATOM   1855 O OD1  . ASP A 1 122 ? -14.763 -16.642 3.172   1 62.9    ? 122 ASP A OD1  1 ? 
ATOM   1856 O OD2  . ASP A 1 122 ? -13.677 -15.494 4.735   1 66.554  ? 122 ASP A OD2  1 ? 
ATOM   1857 H H    . ASP A 1 122 ? -17.704 -13.088 3.655   1 64.256  ? 122 ASP A H    1 c 
ATOM   1858 H HA   . ASP A 1 122 ? -16.207 -14.554 1.932   1 60.548  ? 122 ASP A HA   1 c 
ATOM   1859 H HB2  . ASP A 1 122 ? -15.205 -13.692 3.765   1 65.221  ? 122 ASP A HB2  1 c 
ATOM   1860 H HB3  . ASP A 1 122 ? -16.128 -14.542 4.728   1 65.191  ? 122 ASP A HB3  1 c 
ATOM   1861 N N    . TYR A 1 123 ? -17.818 -16.305 1.418   1 51.703  ? 123 TYR A N    1 ? 
ATOM   1862 C CA   . TYR A 1 123 ? -18.576 -17.494 1.079   1 49.092  ? 123 TYR A CA   1 ? 
ATOM   1863 C C    . TYR A 1 123 ? -17.65  -18.706 1.043   1 49.531  ? 123 TYR A C    1 ? 
ATOM   1864 O O    . TYR A 1 123 ? -18.129 -19.817 0.824   1 48.76   ? 123 TYR A O    1 ? 
ATOM   1865 C CB   . TYR A 1 123 ? -19.287 -17.318 -0.276  1 46.757  ? 123 TYR A CB   1 ? 
ATOM   1866 C CG   . TYR A 1 123 ? -18.427 -17.152 -1.526  1 42.918  ? 123 TYR A CG   1 ? 
ATOM   1867 C CD1  . TYR A 1 123 ? -17.988 -15.904 -1.94   1 40.663  ? 123 TYR A CD1  1 ? 
ATOM   1868 C CD2  . TYR A 1 123 ? -18.04  -18.248 -2.292  1 46.357  ? 123 TYR A CD2  1 ? 
ATOM   1869 C CE1  . TYR A 1 123 ? -17.201 -15.744 -3.067  1 44.164  ? 123 TYR A CE1  1 ? 
ATOM   1870 C CE2  . TYR A 1 123 ? -17.258 -18.101 -3.432  1 41.618  ? 123 TYR A CE2  1 ? 
ATOM   1871 C CZ   . TYR A 1 123 ? -16.833 -16.846 -3.824  1 43.647  ? 123 TYR A CZ   1 ? 
ATOM   1872 O OH   . TYR A 1 123 ? -16.05  -16.687 -4.945  1 46.996  ? 123 TYR A OH   1 ? 
ATOM   1873 H H    . TYR A 1 123 ? -17.522 -15.775 0.736   1 50.9    ? 123 TYR A H    1 c 
ATOM   1874 H HA   . TYR A 1 123 ? -19.267 -17.642 1.778   1 49.222  ? 123 TYR A HA   1 c 
ATOM   1875 H HB2  . TYR A 1 123 ? -19.87  -18.097 -0.41   1 46.451  ? 123 TYR A HB2  1 c 
ATOM   1876 H HB3  . TYR A 1 123 ? -19.878 -16.536 -0.205  1 46.377  ? 123 TYR A HB3  1 c 
ATOM   1877 H HD1  . TYR A 1 123 ? -18.231 -15.141 -1.441  1 42.205  ? 123 TYR A HD1  1 c 
ATOM   1878 H HD2  . TYR A 1 123 ? -18.321 -19.111 -2.035  1 44.436  ? 123 TYR A HD2  1 c 
ATOM   1879 H HE1  . TYR A 1 123 ? -16.922 -14.883 -3.327  1 43.232  ? 123 TYR A HE1  1 c 
ATOM   1880 H HE2  . TYR A 1 123 ? -17.008 -18.859 -3.933  1 43.177  ? 123 TYR A HE2  1 c 
ATOM   1881 N N    . TYR A 1 124 ? -16.337 -18.501 1.23    1 49.537  ? 124 TYR A N    1 ? 
ATOM   1882 C CA   . TYR A 1 124 ? -15.363 -19.567 1.04    1 53.166  ? 124 TYR A CA   1 ? 
ATOM   1883 C C    . TYR A 1 124 ? -15.262 -20.419 2.304   1 55.456  ? 124 TYR A C    1 ? 
ATOM   1884 O O    . TYR A 1 124 ? -14.21  -20.476 2.936   1 60.369  ? 124 TYR A O    1 ? 
ATOM   1885 C CB   . TYR A 1 124 ? -13.979 -19.003 0.717   1 50.688  ? 124 TYR A CB   1 ? 
ATOM   1886 C CG   . TYR A 1 124 ? -13.88  -18.057 -0.467  1 53.82   ? 124 TYR A CG   1 ? 
ATOM   1887 C CD1  . TYR A 1 124 ? -14.124 -16.695 -0.32   1 56.223  ? 124 TYR A CD1  1 ? 
ATOM   1888 C CD2  . TYR A 1 124 ? -13.484 -18.516 -1.716  1 56.25   ? 124 TYR A CD2  1 ? 
ATOM   1889 C CE1  . TYR A 1 124 ? -13.993 -15.819 -1.382  1 55.142  ? 124 TYR A CE1  1 ? 
ATOM   1890 C CE2  . TYR A 1 124 ? -13.348 -17.649 -2.786  1 56.01   ? 124 TYR A CE2  1 ? 
ATOM   1891 C CZ   . TYR A 1 124 ? -13.61  -16.3   -2.62   1 57.2    ? 124 TYR A CZ   1 ? 
ATOM   1892 O OH   . TYR A 1 124 ? -13.499 -15.43  -3.66   1 56.706  ? 124 TYR A OH   1 ? 
ATOM   1893 H H    . TYR A 1 124 ? -16.033 -17.682 1.492   1 50.428  ? 124 TYR A H    1 c 
ATOM   1894 H HA   . TYR A 1 124 ? -15.654 -20.141 0.287   1 52.344  ? 124 TYR A HA   1 c 
ATOM   1895 H HB2  . TYR A 1 124 ? -13.649 -18.528 1.512   1 52.03   ? 124 TYR A HB2  1 c 
ATOM   1896 H HB3  . TYR A 1 124 ? -13.371 -19.759 0.559   1 52.029  ? 124 TYR A HB3  1 c 
ATOM   1897 H HD1  . TYR A 1 124 ? -14.378 -16.359 0.524   1 55.399  ? 124 TYR A HD1  1 c 
ATOM   1898 H HD2  . TYR A 1 124 ? -13.299 -19.434 -1.837  1 55.606  ? 124 TYR A HD2  1 c 
ATOM   1899 H HE1  . TYR A 1 124 ? -14.174 -14.903 -1.268  1 55.925  ? 124 TYR A HE1  1 c 
ATOM   1900 H HE2  . TYR A 1 124 ? -13.096 -17.975 -3.628  1 56.261  ? 124 TYR A HE2  1 c 
ATOM   1901 N N    . ASP A 1 125 ? -16.367 -21.086 2.655   1 56.331  ? 125 ASP A N    1 ? 
ATOM   1902 C CA   . ASP A 1 125 ? -16.439 -22.013 3.768   1 56.332  ? 125 ASP A CA   1 ? 
ATOM   1903 C C    . ASP A 1 125 ? -16.024 -21.314 5.068   1 63.895  ? 125 ASP A C    1 ? 
ATOM   1904 O O    . ASP A 1 125 ? -14.993 -21.635 5.67    1 57.585  ? 125 ASP A O    1 ? 
ATOM   1905 C CB   . ASP A 1 125 ? -15.677 -23.279 3.427   1 62.902  ? 125 ASP A CB   1 ? 
ATOM   1906 C CG   . ASP A 1 125 ? -15.147 -24.019 4.637   1 68.341  ? 125 ASP A CG   1 ? 
ATOM   1907 O OD1  . ASP A 1 125 ? -15.989 -24.38  5.5     1 67.068  ? 125 ASP A OD1  1 ? 
ATOM   1908 O OD2  . ASP A 1 125 ? -13.901 -24.149 4.72    1 55.155  ? 125 ASP A OD2  1 ? 
ATOM   1909 H H    . ASP A 1 125 ? -17.12  -20.974 2.15    1 56.056  ? 125 ASP A H    1 c 
ATOM   1910 H HA   . ASP A 1 125 ? -17.38  -22.286 3.866   1 58.826  ? 125 ASP A HA   1 c 
ATOM   1911 H HB2  . ASP A 1 125 ? -16.28  -23.882 2.945   1 62.496  ? 125 ASP A HB2  1 c 
ATOM   1912 H HB3  . ASP A 1 125 ? -14.922 -23.077 2.836   1 62.407  ? 125 ASP A HB3  1 c 
ATOM   1913 N N    . ASN A 1 126 ? -16.851 -20.343 5.474   1 50.605  ? 126 ASN A N    1 ? 
ATOM   1914 C CA   . ASN A 1 126 ? -16.636 -19.533 6.659   1 49.523  ? 126 ASN A CA   1 ? 
ATOM   1915 C C    . ASN A 1 126 ? -17.921 -19.612 7.475   1 56.116  ? 126 ASN A C    1 ? 
ATOM   1916 O O    . ASN A 1 126 ? -18.951 -19.089 7.058   1 62.149  ? 126 ASN A O    1 ? 
ATOM   1917 C CB   . ASN A 1 126 ? -16.154 -18.144 6.249   1 51.215  ? 126 ASN A CB   1 ? 
ATOM   1918 C CG   . ASN A 1 126 ? -16.028 -17.182 7.41    1 48.84   ? 126 ASN A CG   1 ? 
ATOM   1919 O OD1  . ASN A 1 126 ? -16.717 -17.318 8.418   1 48.023  ? 126 ASN A OD1  1 ? 
ATOM   1920 N ND2  . ASN A 1 126 ? -15.214 -16.153 7.261   1 49.858  ? 126 ASN A ND2  1 ? 
ATOM   1921 H H    . ASN A 1 126 ? -17.596 -20.175 4.972   1 53.316  ? 126 ASN A H    1 c 
ATOM   1922 H HA   . ASN A 1 126 ? -15.913 -19.941 7.185   1 51.38   ? 126 ASN A HA   1 c 
ATOM   1923 H HB2  . ASN A 1 126 ? -15.284 -18.227 5.81    1 50.263  ? 126 ASN A HB2  1 c 
ATOM   1924 H HB3  . ASN A 1 126 ? -16.781 -17.773 5.6     1 50.241  ? 126 ASN A HB3  1 c 
ATOM   1925 H HD21 . ASN A 1 126 ? -15.467 -15.346 7.529   1 49.544  ? 126 ASN A HD21 1 c 
ATOM   1926 H HD22 . ASN A 1 126 ? -14.415 -16.27  6.894   1 49.548  ? 126 ASN A HD22 1 c 
ATOM   1927 N N    . ARG A 1 127 ? -17.863 -20.3   8.62    1 57.172  ? 127 ARG A N    1 ? 
ATOM   1928 C CA   . ARG A 1 127 ? -19.059 -20.669 9.36    1 61.176  ? 127 ARG A CA   1 ? 
ATOM   1929 C C    . ARG A 1 127 ? -19.743 -19.423 9.926   1 62.533  ? 127 ARG A C    1 ? 
ATOM   1930 O O    . ARG A 1 127 ? -20.965 -19.309 9.887   1 63.435  ? 127 ARG A O    1 ? 
ATOM   1931 C CB   . ARG A 1 127 ? -18.675 -21.654 10.465  1 61.325  ? 127 ARG A CB   1 ? 
ATOM   1932 C CG   . ARG A 1 127 ? -19.842 -22.462 11.006  1 68.216  ? 127 ARG A CG   1 ? 
ATOM   1933 C CD   . ARG A 1 127 ? -20.322 -23.541 10.048  1 77.844  ? 127 ARG A CD   1 ? 
ATOM   1934 N NE   . ARG A 1 127 ? -19.375 -24.653 9.887   1 77.86   ? 127 ARG A NE   1 ? 
ATOM   1935 C CZ   . ARG A 1 127 ? -19.725 -25.866 9.445   1 79.062  ? 127 ARG A CZ   1 ? 
ATOM   1936 N NH1  . ARG A 1 127 ? -20.984 -26.117 9.13    1 82.512  ? 127 ARG A NH1  1 ? 
ATOM   1937 N NH2  . ARG A 1 127 ? -18.837 -26.84  9.324   1 75.913  ? 127 ARG A NH2  1 ? 
ATOM   1938 H H    . ARG A 1 127 ? -17.048 -20.535 8.959   1 57.738  ? 127 ARG A H    1 c 
ATOM   1939 H HA   . ARG A 1 127 ? -19.684 -21.109 8.732   1 60.778  ? 127 ARG A HA   1 c 
ATOM   1940 H HB2  . ARG A 1 127 ? -17.999 -22.273 10.116  1 62.827  ? 127 ARG A HB2  1 c 
ATOM   1941 H HB3  . ARG A 1 127 ? -18.267 -21.155 11.205  1 62.808  ? 127 ARG A HB3  1 c 
ATOM   1942 H HG2  . ARG A 1 127 ? -19.573 -22.885 11.851  1 68.612  ? 127 ARG A HG2  1 c 
ATOM   1943 H HG3  . ARG A 1 127 ? -20.59  -21.857 11.203  1 68.591  ? 127 ARG A HG3  1 c 
ATOM   1944 H HD2  . ARG A 1 127 ? -21.17  -23.889 10.391  1 75.558  ? 127 ARG A HD2  1 c 
ATOM   1945 H HD3  . ARG A 1 127 ? -20.5   -23.145 9.173   1 75.382  ? 127 ARG A HD3  1 c 
ATOM   1946 H HE   . ARG A 1 127 ? -18.54  -24.521 10.095  1 77.89   ? 127 ARG A HE   1 c 
ATOM   1947 H HH11 . ARG A 1 127 ? -21.347 -25.723 8.426   1 81.435  ? 127 ARG A HH11 1 c 
ATOM   1948 H HH12 . ARG A 1 127 ? -21.458 -26.677 9.623   1 81.435  ? 127 ARG A HH12 1 c 
ATOM   1949 H HH21 . ARG A 1 127 ? -18.226 -26.958 9.949   1 76.864  ? 127 ARG A HH21 1 c 
ATOM   1950 H HH22 . ARG A 1 127 ? -18.873 -27.376 8.625   1 76.865  ? 127 ARG A HH22 1 c 
ATOM   1951 N N    . VAL A 1 128 ? -18.948 -18.486 10.443  1 63.691  ? 128 VAL A N    1 ? 
ATOM   1952 C CA   . VAL A 1 128 ? -19.489 -17.294 11.077  1 74.23   ? 128 VAL A CA   1 ? 
ATOM   1953 C C    . VAL A 1 128 ? -20.124 -16.376 10.024  1 73.299  ? 128 VAL A C    1 ? 
ATOM   1954 O O    . VAL A 1 128 ? -21.152 -15.76  10.291  1 67.232  ? 128 VAL A O    1 ? 
ATOM   1955 C CB   . VAL A 1 128 ? -18.412 -16.595 11.932  1 77.309  ? 128 VAL A CB   1 ? 
ATOM   1956 C CG1  . VAL A 1 128 ? -18.883 -15.253 12.502  1 77.381  ? 128 VAL A CG1  1 ? 
ATOM   1957 C CG2  . VAL A 1 128 ? -17.955 -17.519 13.063  1 76.808  ? 128 VAL A CG2  1 ? 
ATOM   1958 H H    . VAL A 1 128 ? -18.041 -18.59  10.406  1 65.817  ? 128 VAL A H    1 c 
ATOM   1959 H HA   . VAL A 1 128 ? -20.2   -17.581 11.684  1 72.341  ? 128 VAL A HA   1 c 
ATOM   1960 H HB   . VAL A 1 128 ? -17.638 -16.424 11.345  1 76.586  ? 128 VAL A HB   1 c 
ATOM   1961 H HG11 . VAL A 1 128 ? -19.81  -15.329 12.786  1 77.354  ? 128 VAL A HG11 1 c 
ATOM   1962 H HG12 . VAL A 1 128 ? -18.81  -14.566 11.819  1 77.339  ? 128 VAL A HG12 1 c 
ATOM   1963 H HG13 . VAL A 1 128 ? -18.332 -15.008 13.264  1 77.349  ? 128 VAL A HG13 1 c 
ATOM   1964 H HG21 . VAL A 1 128 ? -17.355 -17.037 13.657  1 76.911  ? 128 VAL A HG21 1 c 
ATOM   1965 H HG22 . VAL A 1 128 ? -17.49  -18.286 12.691  1 76.786  ? 128 VAL A HG22 1 c 
ATOM   1966 H HG23 . VAL A 1 128 ? -18.73  -17.825 13.566  1 76.885  ? 128 VAL A HG23 1 c 
ATOM   1967 N N    . ALA A 1 129 ? -19.546 -16.315 8.819   1 66.898  ? 129 ALA A N    1 ? 
ATOM   1968 C CA   . ALA A 1 129 ? -20.167 -15.592 7.717   1 67.612  ? 129 ALA A CA   1 ? 
ATOM   1969 C C    . ALA A 1 129 ? -21.575 -16.124 7.461   1 61.58   ? 129 ALA A C    1 ? 
ATOM   1970 O O    . ALA A 1 129 ? -22.518 -15.326 7.402   1 51.08   ? 129 ALA A O    1 ? 
ATOM   1971 C CB   . ALA A 1 129 ? -19.304 -15.661 6.483   1 71.232  ? 129 ALA A CB   1 ? 
ATOM   1972 H H    . ALA A 1 129 ? -18.737 -16.717 8.682   1 68.566  ? 129 ALA A H    1 c 
ATOM   1973 H HA   . ALA A 1 129 ? -20.255 -14.644 7.985   1 66.815  ? 129 ALA A HA   1 c 
ATOM   1974 H HB1  . ALA A 1 129 ? -18.505 -15.124 6.613   1 70.1    ? 129 ALA A HB1  1 c 
ATOM   1975 H HB2  . ALA A 1 129 ? -19.048 -16.582 6.314   1 70.056  ? 129 ALA A HB2  1 c 
ATOM   1976 H HB3  . ALA A 1 129 ? -19.798 -15.321 5.719   1 70.031  ? 129 ALA A HB3  1 c 
ATOM   1977 N N    . LEU A 1 130 ? -21.703 -17.461 7.398   1 55.703  ? 130 LEU A N    1 ? 
ATOM   1978 C CA   . LEU A 1 130 ? -22.975 -18.118 7.143   1 56.292  ? 130 LEU A CA   1 ? 
ATOM   1979 C C    . LEU A 1 130 ? -23.956 -17.84  8.279   1 61.546  ? 130 LEU A C    1 ? 
ATOM   1980 O O    . LEU A 1 130 ? -25.132 -17.604 8.007   1 74.078  ? 130 LEU A O    1 ? 
ATOM   1981 C CB   . LEU A 1 130 ? -22.783 -19.618 6.907   1 49.901  ? 130 LEU A CB   1 ? 
ATOM   1982 C CG   . LEU A 1 130 ? -24.041 -20.446 6.622   1 56.038  ? 130 LEU A CG   1 ? 
ATOM   1983 C CD1  . LEU A 1 130 ? -24.736 -19.989 5.348   1 59.52   ? 130 LEU A CD1  1 ? 
ATOM   1984 C CD2  . LEU A 1 130 ? -23.698 -21.915 6.526   1 54.194  ? 130 LEU A CD2  1 ? 
ATOM   1985 H H    . LEU A 1 130 ? -20.961 -17.983 7.508   1 57.257  ? 130 LEU A H    1 c 
ATOM   1986 H HA   . LEU A 1 130 ? -23.352 -17.717 6.319   1 56.022  ? 130 LEU A HA   1 c 
ATOM   1987 H HB2  . LEU A 1 130 ? -22.163 -19.73  6.15    1 52.672  ? 130 LEU A HB2  1 c 
ATOM   1988 H HB3  . LEU A 1 130 ? -22.34  -19.996 7.701   1 52.713  ? 130 LEU A HB3  1 c 
ATOM   1989 H HG   . LEU A 1 130 ? -24.673 -20.33  7.378   1 55.222  ? 130 LEU A HG   1 c 
ATOM   1990 H HD11 . LEU A 1 130 ? -25.02  -19.065 5.442   1 58.44   ? 130 LEU A HD11 1 c 
ATOM   1991 H HD12 . LEU A 1 130 ? -25.513 -20.547 5.185   1 58.451  ? 130 LEU A HD12 1 c 
ATOM   1992 H HD13 . LEU A 1 130 ? -24.122 -20.064 4.598   1 58.461  ? 130 LEU A HD13 1 c 
ATOM   1993 H HD21 . LEU A 1 130 ? -23.27  -22.203 7.35    1 54.738  ? 130 LEU A HD21 1 c 
ATOM   1994 H HD22 . LEU A 1 130 ? -23.092 -22.059 5.78    1 54.738  ? 130 LEU A HD22 1 c 
ATOM   1995 H HD23 . LEU A 1 130 ? -24.51  -22.43  6.387   1 54.748  ? 130 LEU A HD23 1 c 
ATOM   1996 N N    . ASP A 1 131 ? -23.477 -17.87  9.532   1 64.25   ? 131 ASP A N    1 ? 
ATOM   1997 C CA   . ASP A 1 131 ? -24.352 -17.7   10.686  1 65.278  ? 131 ASP A CA   1 ? 
ATOM   1998 C C    . ASP A 1 131 ? -24.951 -16.294 10.658  1 54.104  ? 131 ASP A C    1 ? 
ATOM   1999 O O    . ASP A 1 131 ? -26.15  -16.136 10.862  1 60.412  ? 131 ASP A O    1 ? 
ATOM   2000 C CB   . ASP A 1 131 ? -23.647 -18.034 11.999  1 79.483  ? 131 ASP A CB   1 ? 
ATOM   2001 C CG   . ASP A 1 131 ? -24.435 -17.867 13.303  1 91.524  ? 131 ASP A CG   1 ? 
ATOM   2002 O OD1  . ASP A 1 131 ? -25.654 -17.592 13.264  1 109.166 ? 131 ASP A OD1  1 ? 
ATOM   2003 O OD2  . ASP A 1 131 ? -23.82  -18.003 14.379  1 113.752 ? 131 ASP A OD2  1 ? 
ATOM   2004 H H    . ASP A 1 131 ? -22.585 -18.01  9.675   1 63.803  ? 131 ASP A H    1 c 
ATOM   2005 H HA   . ASP A 1 131 ? -25.09  -18.345 10.599  1 65.23   ? 131 ASP A HA   1 c 
ATOM   2006 H HB2  . ASP A 1 131 ? -23.347 -18.966 11.953  1 78.468  ? 131 ASP A HB2  1 c 
ATOM   2007 H HB3  . ASP A 1 131 ? -22.847 -17.471 12.064  1 78.468  ? 131 ASP A HB3  1 c 
ATOM   2008 N N    . THR A 1 132 ? -24.11  -15.284 10.413  1 53.677  ? 132 THR A N    1 ? 
ATOM   2009 C CA   . THR A 1 132 ? -24.561 -13.909 10.328  1 57.083  ? 132 THR A CA   1 ? 
ATOM   2010 C C    . THR A 1 132 ? -25.652 -13.803 9.257   1 72.665  ? 132 THR A C    1 ? 
ATOM   2011 O O    . THR A 1 132 ? -26.735 -13.281 9.527   1 64.823  ? 132 THR A O    1 ? 
ATOM   2012 C CB   . THR A 1 132 ? -23.358 -13.021 10.012  1 60.122  ? 132 THR A CB   1 ? 
ATOM   2013 O OG1  . THR A 1 132 ? -22.413 -13.306 11.039  1 60.179  ? 132 THR A OG1  1 ? 
ATOM   2014 C CG2  . THR A 1 132 ? -23.695 -11.54  9.979   1 63.613  ? 132 THR A CG2  1 ? 
ATOM   2015 H H    . THR A 1 132 ? -23.219 -15.459 10.31   1 54.695  ? 132 THR A H    1 c 
ATOM   2016 H HA   . THR A 1 132 ? -24.935 -13.644 11.196  1 59.695  ? 132 THR A HA   1 c 
ATOM   2017 H HB   . THR A 1 132 ? -22.978 -13.283 9.14    1 60.191  ? 132 THR A HB   1 c 
ATOM   2018 H HG21 . THR A 1 132 ? -22.872 -11.022 9.973   1 62.595  ? 132 THR A HG21 1 c 
ATOM   2019 H HG22 . THR A 1 132 ? -24.216 -11.307 10.762  1 62.67   ? 132 THR A HG22 1 c 
ATOM   2020 H HG23 . THR A 1 132 ? -24.207 -11.339 9.178   1 62.63   ? 132 THR A HG23 1 c 
ATOM   2021 N N    . VAL A 1 133 ? -25.364 -14.336 8.056   1 71.802  ? 133 VAL A N    1 ? 
ATOM   2022 C CA   . VAL A 1 133 ? -26.276 -14.27  6.924   1 67.185  ? 133 VAL A CA   1 ? 
ATOM   2023 C C    . VAL A 1 133 ? -27.593 -14.948 7.285   1 62.423  ? 133 VAL A C    1 ? 
ATOM   2024 O O    . VAL A 1 133 ? -28.661 -14.439 6.94    1 62.99   ? 133 VAL A O    1 ? 
ATOM   2025 C CB   . VAL A 1 133 ? -25.668 -14.861 5.632   1 69.494  ? 133 VAL A CB   1 ? 
ATOM   2026 C CG1  . VAL A 1 133 ? -26.578 -15.857 4.927   1 63.937  ? 133 VAL A CG1  1 ? 
ATOM   2027 C CG2  . VAL A 1 133 ? -25.249 -13.76  4.672   1 79.256  ? 133 VAL A CG2  1 ? 
ATOM   2028 H H    . VAL A 1 133 ? -24.556 -14.747 7.942   1 70.682  ? 133 VAL A H    1 c 
ATOM   2029 H HA   . VAL A 1 133 ? -26.468 -13.326 6.762   1 67.636  ? 133 VAL A HA   1 c 
ATOM   2030 H HB   . VAL A 1 133 ? -24.852 -15.35  5.889   1 69.714  ? 133 VAL A HB   1 c 
ATOM   2031 H HG11 . VAL A 1 133 ? -27.442 -15.449 4.747   1 65.464  ? 133 VAL A HG11 1 c 
ATOM   2032 H HG12 . VAL A 1 133 ? -26.696 -16.648 5.478   1 65.443  ? 133 VAL A HG12 1 c 
ATOM   2033 H HG13 . VAL A 1 133 ? -26.17  -16.116 4.086   1 65.451  ? 133 VAL A HG13 1 c 
ATOM   2034 H HG21 . VAL A 1 133 ? -25.005 -14.15  3.815   1 75.962  ? 133 VAL A HG21 1 c 
ATOM   2035 H HG22 . VAL A 1 133 ? -24.486 -13.288 5.038   1 76.067  ? 133 VAL A HG22 1 c 
ATOM   2036 H HG23 . VAL A 1 133 ? -25.985 -13.138 4.544   1 76.093  ? 133 VAL A HG23 1 c 
ATOM   2037 N N    . ASN A 1 134 ? -27.509 -16.102 7.95    1 58.234  ? 134 ASN A N    1 ? 
ATOM   2038 C CA   . ASN A 1 134 ? -28.705 -16.869 8.261   1 62.875  ? 134 ASN A CA   1 ? 
ATOM   2039 C C    . ASN A 1 134 ? -29.663 -16.086 9.169   1 67.421  ? 134 ASN A C    1 ? 
ATOM   2040 O O    . ASN A 1 134 ? -30.883 -16.183 9.017   1 70.809  ? 134 ASN A O    1 ? 
ATOM   2041 C CB   . ASN A 1 134 ? -28.318 -18.24  8.794   1 60.206  ? 134 ASN A CB   1 ? 
ATOM   2042 C CG   . ASN A 1 134 ? -27.971 -19.2   7.678   1 68.626  ? 134 ASN A CG   1 ? 
ATOM   2043 O OD1  . ASN A 1 134 ? -28.135 -18.885 6.487   1 63.262  ? 134 ASN A OD1  1 ? 
ATOM   2044 N ND2  . ASN A 1 134 ? -27.519 -20.39  8.042   1 65.605  ? 134 ASN A ND2  1 ? 
ATOM   2045 H H    . ASN A 1 134 ? -26.693 -16.426 8.203   1 60.372  ? 134 ASN A H    1 c 
ATOM   2046 H HA   . ASN A 1 134 ? -29.186 -17.014 7.416   1 62.298  ? 134 ASN A HA   1 c 
ATOM   2047 H HB2  . ASN A 1 134 ? -27.55  -18.151 9.394   1 62.643  ? 134 ASN A HB2  1 c 
ATOM   2048 H HB3  . ASN A 1 134 ? -29.063 -18.607 9.31    1 62.679  ? 134 ASN A HB3  1 c 
ATOM   2049 H HD21 . ASN A 1 134 ? -27     -20.852 7.491   1 66.41   ? 134 ASN A HD21 1 c 
ATOM   2050 H HD22 . ASN A 1 134 ? -27.737 -20.725 8.834   1 66.451  ? 134 ASN A HD22 1 c 
ATOM   2051 N N    . GLN A 1 135 ? -29.111 -15.282 10.086  1 59.081  ? 135 GLN A N    1 ? 
ATOM   2052 C CA   . GLN A 1 135 ? -29.921 -14.458 10.975  1 72.628  ? 135 GLN A CA   1 ? 
ATOM   2053 C C    . GLN A 1 135 ? -30.607 -13.351 10.176  1 62.463  ? 135 GLN A C    1 ? 
ATOM   2054 O O    . GLN A 1 135 ? -31.808 -13.135 10.315  1 63.007  ? 135 GLN A O    1 ? 
ATOM   2055 C CB   . GLN A 1 135 ? -29.072 -13.88  12.108  1 77.005  ? 135 GLN A CB   1 ? 
ATOM   2056 C CG   . GLN A 1 135 ? -28.599 -14.927 13.111  1 85.426  ? 135 GLN A CG   1 ? 
ATOM   2057 C CD   . GLN A 1 135 ? -27.769 -14.323 14.219  1 97.324  ? 135 GLN A CD   1 ? 
ATOM   2058 O OE1  . GLN A 1 135 ? -28.166 -14.33  15.39   1 103.715 ? 135 GLN A OE1  1 ? 
ATOM   2059 N NE2  . GLN A 1 135 ? -26.622 -13.769 13.853  1 97.27   ? 135 GLN A NE2  1 ? 
ATOM   2060 H H    . GLN A 1 135 ? -28.202 -15.255 10.173  1 64      ? 135 GLN A H    1 c 
ATOM   2061 H HA   . GLN A 1 135 ? -30.622 -15.033 11.378  1 68.602  ? 135 GLN A HA   1 c 
ATOM   2062 H HB2  . GLN A 1 135 ? -28.291 -13.434 11.72   1 77.704  ? 135 GLN A HB2  1 c 
ATOM   2063 H HB3  . GLN A 1 135 ? -29.598 -13.201 12.582  1 77.697  ? 135 GLN A HB3  1 c 
ATOM   2064 H HG2  . GLN A 1 135 ? -29.378 -15.375 13.504  1 85.956  ? 135 GLN A HG2  1 c 
ATOM   2065 H HG3  . GLN A 1 135 ? -28.066 -15.605 12.646  1 85.827  ? 135 GLN A HG3  1 c 
ATOM   2066 H HE21 . GLN A 1 135 ? -26.31  -13.065 14.293  1 96.932  ? 135 GLN A HE21 1 c 
ATOM   2067 H HE22 . GLN A 1 135 ? -26.166 -14.105 13.171  1 96.75   ? 135 GLN A HE22 1 c 
ATOM   2068 N N    . LEU A 1 136 ? -29.827 -12.675 9.326   1 60.457  ? 136 LEU A N    1 ? 
ATOM   2069 C CA   . LEU A 1 136 ? -30.352 -11.646 8.446   1 61.52   ? 136 LEU A CA   1 ? 
ATOM   2070 C C    . LEU A 1 136 ? -31.449 -12.227 7.562   1 55.744  ? 136 LEU A C    1 ? 
ATOM   2071 O O    . LEU A 1 136 ? -32.436 -11.551 7.339   1 56.098  ? 136 LEU A O    1 ? 
ATOM   2072 C CB   . LEU A 1 136 ? -29.258 -10.988 7.607   1 64.603  ? 136 LEU A CB   1 ? 
ATOM   2073 C CG   . LEU A 1 136 ? -29.717 -9.87   6.665   1 62.915  ? 136 LEU A CG   1 ? 
ATOM   2074 C CD1  . LEU A 1 136 ? -30.432 -8.746  7.417   1 66.766  ? 136 LEU A CD1  1 ? 
ATOM   2075 C CD2  . LEU A 1 136 ? -28.523 -9.344  5.899   1 60.506  ? 136 LEU A CD2  1 ? 
ATOM   2076 H H    . LEU A 1 136 ? -28.93  -12.852 9.303   1 61.249  ? 136 LEU A H    1 c 
ATOM   2077 H HA   . LEU A 1 136 ? -30.766 -10.954 9.021   1 60.741  ? 136 LEU A HA   1 c 
ATOM   2078 H HB2  . LEU A 1 136 ? -28.581 -10.619 8.22    1 63.503  ? 136 LEU A HB2  1 c 
ATOM   2079 H HB3  . LEU A 1 136 ? -28.822 -11.688 7.068   1 63.503  ? 136 LEU A HB3  1 c 
ATOM   2080 H HG   . LEU A 1 136 ? -30.352 -10.254 6.007   1 63.411  ? 136 LEU A HG   1 c 
ATOM   2081 H HD11 . LEU A 1 136 ? -31.322 -9.042  7.676   1 65.603  ? 136 LEU A HD11 1 c 
ATOM   2082 H HD12 . LEU A 1 136 ? -30.507 -7.965  6.843   1 65.651  ? 136 LEU A HD12 1 c 
ATOM   2083 H HD13 . LEU A 1 136 ? -29.926 -8.513  8.214   1 65.618  ? 136 LEU A HD13 1 c 
ATOM   2084 H HD21 . LEU A 1 136 ? -28.117 -10.067 5.393   1 61.217  ? 136 LEU A HD21 1 c 
ATOM   2085 H HD22 . LEU A 1 136 ? -27.872 -8.98   6.522   1 61.217  ? 136 LEU A HD22 1 c 
ATOM   2086 H HD23 . LEU A 1 136 ? -28.811 -8.645  5.288   1 61.239  ? 136 LEU A HD23 1 c 
ATOM   2087 N N    . LEU A 1 137 ? -31.29  -13.475 7.105   1 56.663  ? 137 LEU A N    1 ? 
ATOM   2088 C CA   . LEU A 1 137 ? -32.284 -14.113 6.258   1 57.307  ? 137 LEU A CA   1 ? 
ATOM   2089 C C    . LEU A 1 137 ? -33.548 -14.439 7.046   1 59.781  ? 137 LEU A C    1 ? 
ATOM   2090 O O    . LEU A 1 137 ? -34.637 -14.366 6.492   1 66.158  ? 137 LEU A O    1 ? 
ATOM   2091 C CB   . LEU A 1 137 ? -31.748 -15.381 5.595   1 55.754  ? 137 LEU A CB   1 ? 
ATOM   2092 C CG   . LEU A 1 137 ? -30.74  -15.199 4.46    1 53.498  ? 137 LEU A CG   1 ? 
ATOM   2093 C CD1  . LEU A 1 137 ? -30.312 -16.573 3.96    1 55.555  ? 137 LEU A CD1  1 ? 
ATOM   2094 C CD2  . LEU A 1 137 ? -31.282 -14.375 3.317   1 51.231  ? 137 LEU A CD2  1 ? 
ATOM   2095 H H    . LEU A 1 137 ? -30.531 -13.939 7.313   1 56.658  ? 137 LEU A H    1 c 
ATOM   2096 H HA   . LEU A 1 137 ? -32.534 -13.468 5.55    1 57.261  ? 137 LEU A HA   1 c 
ATOM   2097 H HB2  . LEU A 1 137 ? -31.329 -15.936 6.293   1 55.587  ? 137 LEU A HB2  1 c 
ATOM   2098 H HB3  . LEU A 1 137 ? -32.514 -15.891 5.244   1 55.602  ? 137 LEU A HB3  1 c 
ATOM   2099 H HG   . LEU A 1 137 ? -29.942 -14.738 4.82    1 53.893  ? 137 LEU A HG   1 c 
ATOM   2100 H HD11 . LEU A 1 137 ? -30.001 -17.11  4.708   1 54.934  ? 137 LEU A HD11 1 c 
ATOM   2101 H HD12 . LEU A 1 137 ? -29.593 -16.473 3.314   1 54.894  ? 137 LEU A HD12 1 c 
ATOM   2102 H HD13 . LEU A 1 137 ? -31.067 -17.015 3.536   1 54.931  ? 137 LEU A HD13 1 c 
ATOM   2103 H HD21 . LEU A 1 137 ? -31.254 -13.433 3.554   1 51.939  ? 137 LEU A HD21 1 c 
ATOM   2104 H HD22 . LEU A 1 137 ? -32.2   -14.635 3.136   1 51.913  ? 137 LEU A HD22 1 c 
ATOM   2105 H HD23 . LEU A 1 137 ? -30.741 -14.523 2.523   1 51.943  ? 137 LEU A HD23 1 c 
ATOM   2106 N N    . ASP A 1 138 ? -33.408 -14.872 8.302   1 63.545  ? 138 ASP A N    1 ? 
ATOM   2107 C CA   . ASP A 1 138 ? -34.575 -15.191 9.111   1 63.955  ? 138 ASP A CA   1 ? 
ATOM   2108 C C    . ASP A 1 138 ? -35.463 -13.953 9.295   1 60.918  ? 138 ASP A C    1 ? 
ATOM   2109 O O    . ASP A 1 138 ? -36.685 -14.043 9.213   1 61.496  ? 138 ASP A O    1 ? 
ATOM   2110 C CB   . ASP A 1 138 ? -34.182 -15.84  10.431  1 76.223  ? 138 ASP A CB   1 ? 
ATOM   2111 C CG   . ASP A 1 138 ? -33.819 -17.322 10.37   1 86.021  ? 138 ASP A CG   1 ? 
ATOM   2112 O OD1  . ASP A 1 138 ? -34.571 -18.104 9.733   1 86.081  ? 138 ASP A OD1  1 ? 
ATOM   2113 O OD2  . ASP A 1 138 ? -32.807 -17.693 10.999  1 80.679  ? 138 ASP A OD2  1 ? 
ATOM   2114 H H    . ASP A 1 138 ? -32.574 -14.984 8.659   1 62.807  ? 138 ASP A H    1 c 
ATOM   2115 H HA   . ASP A 1 138 ? -35.102 -15.86  8.62    1 65.596  ? 138 ASP A HA   1 c 
ATOM   2116 H HB2  . ASP A 1 138 ? -33.419 -15.352 10.806  1 75.204  ? 138 ASP A HB2  1 c 
ATOM   2117 H HB3  . ASP A 1 138 ? -34.929 -15.747 11.059  1 75.192  ? 138 ASP A HB3  1 c 
ATOM   2118 N N    . GLU A 1 139 ? -34.844 -12.802 9.571   1 55.636  ? 139 GLU A N    1 ? 
ATOM   2119 C CA   . GLU A 1 139 ? -35.558 -11.546 9.706   1 60.071  ? 139 GLU A CA   1 ? 
ATOM   2120 C C    . GLU A 1 139 ? -36.295 -11.25  8.392   1 70.299  ? 139 GLU A C    1 ? 
ATOM   2121 O O    . GLU A 1 139 ? -37.494 -10.973 8.426   1 62.627  ? 139 GLU A O    1 ? 
ATOM   2122 C CB   . GLU A 1 139 ? -34.544 -10.481 10.136  1 58.897  ? 139 GLU A CB   1 ? 
ATOM   2123 C CG   . GLU A 1 139 ? -35.079 -9.054  10.119  1 57.734  ? 139 GLU A CG   1 ? 
ATOM   2124 C CD   . GLU A 1 139 ? -34.041 -8.04   10.545  1 68.33   ? 139 GLU A CD   1 ? 
ATOM   2125 O OE1  . GLU A 1 139 ? -33.499 -7.398  9.619   1 63.692  ? 139 GLU A OE1  1 ? 
ATOM   2126 O OE2  . GLU A 1 139 ? -33.779 -7.891  11.77   1 79.27   ? 139 GLU A OE2  1 ? 
ATOM   2127 H H    . GLU A 1 139 ? -33.938 -12.806 9.698   1 57.935  ? 139 GLU A H    1 c 
ATOM   2128 H HA   . GLU A 1 139 ? -36.231 -11.649 10.427  1 60.689  ? 139 GLU A HA   1 c 
ATOM   2129 H HB2  . GLU A 1 139 ? -34.233 -10.691 11.041  1 58.891  ? 139 GLU A HB2  1 c 
ATOM   2130 H HB3  . GLU A 1 139 ? -33.77  -10.524 9.537   1 58.884  ? 139 GLU A HB3  1 c 
ATOM   2131 H HG2  . GLU A 1 139 ? -35.384 -8.829  9.215   1 60.361  ? 139 GLU A HG2  1 c 
ATOM   2132 H HG3  . GLU A 1 139 ? -35.849 -8.99   10.724  1 60.303  ? 139 GLU A HG3  1 c 
ATOM   2133 N N    . VAL A 1 140 ? -35.58  -11.374 7.251   1 64.359  ? 140 VAL A N    1 ? 
ATOM   2134 C CA   . VAL A 1 140 ? -36.121 -11.123 5.918   1 62.884  ? 140 VAL A CA   1 ? 
ATOM   2135 C C    . VAL A 1 140 ? -37.242 -12.112 5.589   1 57.947  ? 140 VAL A C    1 ? 
ATOM   2136 O O    . VAL A 1 140 ? -38.288 -11.695 5.105   1 58.238  ? 140 VAL A O    1 ? 
ATOM   2137 C CB   . VAL A 1 140 ? -35.034 -11.112 4.822   1 57.438  ? 140 VAL A CB   1 ? 
ATOM   2138 C CG1  . VAL A 1 140 ? -35.613 -11.108 3.412   1 53.437  ? 140 VAL A CG1  1 ? 
ATOM   2139 C CG2  . VAL A 1 140 ? -34.079 -9.934  4.988   1 60.072  ? 140 VAL A CG2  1 ? 
ATOM   2140 H H    . VAL A 1 140 ? -34.702 -11.619 7.314   1 65.221  ? 140 VAL A H    1 c 
ATOM   2141 H HA   . VAL A 1 140 ? -36.519 -10.231 5.937   1 61.17   ? 140 VAL A HA   1 c 
ATOM   2142 H HB   . VAL A 1 140 ? -34.509 -11.94  4.927   1 58.11   ? 140 VAL A HB   1 c 
ATOM   2143 H HG11 . VAL A 1 140 ? -36.384 -10.516 3.377   1 54.603  ? 140 VAL A HG11 1 c 
ATOM   2144 H HG12 . VAL A 1 140 ? -35.885 -12.008 3.167   1 54.603  ? 140 VAL A HG12 1 c 
ATOM   2145 H HG13 . VAL A 1 140 ? -34.939 -10.795 2.786   1 54.587  ? 140 VAL A HG13 1 c 
ATOM   2146 H HG21 . VAL A 1 140 ? -33.247 -10.123 4.522   1 59.283  ? 140 VAL A HG21 1 c 
ATOM   2147 H HG22 . VAL A 1 140 ? -33.895 -9.791  5.931   1 59.306  ? 140 VAL A HG22 1 c 
ATOM   2148 H HG23 . VAL A 1 140 ? -34.483 -9.132  4.614   1 59.256  ? 140 VAL A HG23 1 c 
ATOM   2149 N N    . LEU A 1 141 ? -37.061 -13.405 5.854   1 52.239  ? 141 LEU A N    1 ? 
ATOM   2150 C CA   . LEU A 1 141 ? -38.133 -14.359 5.581   1 57.609  ? 141 LEU A CA   1 ? 
ATOM   2151 C C    . LEU A 1 141 ? -39.398 -14.031 6.392   1 61.444  ? 141 LEU A C    1 ? 
ATOM   2152 O O    . LEU A 1 141 ? -40.514 -14.243 5.921   1 61.93   ? 141 LEU A O    1 ? 
ATOM   2153 C CB   . LEU A 1 141 ? -37.644 -15.78  5.852   1 56.031  ? 141 LEU A CB   1 ? 
ATOM   2154 C CG   . LEU A 1 141 ? -36.512 -16.297 4.949   1 63.659  ? 141 LEU A CG   1 ? 
ATOM   2155 C CD1  . LEU A 1 141 ? -35.724 -17.427 5.628   1 59.823  ? 141 LEU A CD1  1 ? 
ATOM   2156 C CD2  . LEU A 1 141 ? -37.021 -16.749 3.583   1 55.72   ? 141 LEU A CD2  1 ? 
ATOM   2157 H H    . LEU A 1 141 ? -36.271 -13.701 6.204   1 54.945  ? 141 LEU A H    1 c 
ATOM   2158 H HA   . LEU A 1 141 ? -38.363 -14.286 4.62    1 56.916  ? 141 LEU A HA   1 c 
ATOM   2159 H HB2  . LEU A 1 141 ? -37.34  -15.825 6.788   1 58.071  ? 141 LEU A HB2  1 c 
ATOM   2160 H HB3  . LEU A 1 141 ? -38.412 -16.39  5.763   1 58.064  ? 141 LEU A HB3  1 c 
ATOM   2161 H HG   . LEU A 1 141 ? -35.884 -15.55  4.788   1 59.909  ? 141 LEU A HG   1 c 
ATOM   2162 H HD11 . LEU A 1 141 ? -35.36  -17.109 6.471   1 60.899  ? 141 LEU A HD11 1 c 
ATOM   2163 H HD12 . LEU A 1 141 ? -34.997 -17.71  5.048   1 60.91   ? 141 LEU A HD12 1 c 
ATOM   2164 H HD13 . LEU A 1 141 ? -36.315 -18.18  5.796   1 60.914  ? 141 LEU A HD13 1 c 
ATOM   2165 H HD21 . LEU A 1 141 ? -37.599 -16.063 3.208   1 57.931  ? 141 LEU A HD21 1 c 
ATOM   2166 H HD22 . LEU A 1 141 ? -37.523 -17.575 3.681   1 57.937  ? 141 LEU A HD22 1 c 
ATOM   2167 H HD23 . LEU A 1 141 ? -36.267 -16.897 2.988   1 57.905  ? 141 LEU A HD23 1 c 
ATOM   2168 N N    . ASP A 1 142 ? -39.225 -13.528 7.622   1 66.537  ? 142 ASP A N    1 ? 
ATOM   2169 C CA   . ASP A 1 142 ? -40.339 -13.161 8.494   1 73.335  ? 142 ASP A CA   1 ? 
ATOM   2170 C C    . ASP A 1 142 ? -41.071 -11.916 7.966   1 59.012  ? 142 ASP A C    1 ? 
ATOM   2171 O O    . ASP A 1 142 ? -42.287 -11.941 7.84    1 50.813  ? 142 ASP A O    1 ? 
ATOM   2172 C CB   . ASP A 1 142 ? -39.889 -13.008 9.948   1 79.812  ? 142 ASP A CB   1 ? 
ATOM   2173 C CG   . ASP A 1 142 ? -39.669 -14.295 10.744  1 85.736  ? 142 ASP A CG   1 ? 
ATOM   2174 O OD1  . ASP A 1 142 ? -40.264 -15.338 10.386  1 75.624  ? 142 ASP A OD1  1 ? 
ATOM   2175 O OD2  . ASP A 1 142 ? -38.884 -14.254 11.722  1 90.308  ? 142 ASP A OD2  1 ? 
ATOM   2176 H H    . ASP A 1 142 ? -38.376 -13.424 7.941   1 66.676  ? 142 ASP A H    1 c 
ATOM   2177 H HA   . ASP A 1 142 ? -40.983 -13.904 8.483   1 70.122  ? 142 ASP A HA   1 c 
ATOM   2178 H HB2  . ASP A 1 142 ? -39.054 -12.497 9.969   1 79.372  ? 142 ASP A HB2  1 c 
ATOM   2179 H HB3  . ASP A 1 142 ? -40.564 -12.482 10.426  1 79.421  ? 142 ASP A HB3  1 c 
ATOM   2180 N N    . LEU A 1 143 ? -40.32  -10.848 7.671   1 48.909  ? 143 LEU A N    1 ? 
ATOM   2181 C CA   . LEU A 1 143 ? -40.839 -9.598  7.144   1 59.026  ? 143 LEU A CA   1 ? 
ATOM   2182 C C    . LEU A 1 143 ? -41.726 -9.831  5.922   1 66.116  ? 143 LEU A C    1 ? 
ATOM   2183 O O    . LEU A 1 143 ? -42.772 -9.191  5.825   1 64.985  ? 143 LEU A O    1 ? 
ATOM   2184 C CB   . LEU A 1 143 ? -39.704 -8.643  6.775   1 59.398  ? 143 LEU A CB   1 ? 
ATOM   2185 C CG   . LEU A 1 143 ? -38.964 -7.962  7.927   1 65.398  ? 143 LEU A CG   1 ? 
ATOM   2186 C CD1  . LEU A 1 143 ? -37.72  -7.215  7.427   1 68.079  ? 143 LEU A CD1  1 ? 
ATOM   2187 C CD2  . LEU A 1 143 ? -39.886 -7.003  8.673   1 71.776  ? 143 LEU A CD2  1 ? 
ATOM   2188 H H    . LEU A 1 143 ? -39.419 -10.906 7.819   1 53.652  ? 143 LEU A H    1 c 
ATOM   2189 H HA   . LEU A 1 143 ? -41.395 -9.181  7.848   1 58.321  ? 143 LEU A HA   1 c 
ATOM   2190 H HB2  . LEU A 1 143 ? -39.046 -9.145  6.241   1 60.596  ? 143 LEU A HB2  1 c 
ATOM   2191 H HB3  . LEU A 1 143 ? -40.072 -7.941  6.189   1 60.705  ? 143 LEU A HB3  1 c 
ATOM   2192 H HG   . LEU A 1 143 ? -38.67  -8.661  8.564   1 65.837  ? 143 LEU A HG   1 c 
ATOM   2193 H HD11 . LEU A 1 143 ? -37.139 -7.832  6.952   1 67.266  ? 143 LEU A HD11 1 c 
ATOM   2194 H HD12 . LEU A 1 143 ? -37.241 -6.839  8.185   1 67.279  ? 143 LEU A HD12 1 c 
ATOM   2195 H HD13 . LEU A 1 143 ? -37.99  -6.499  6.828   1 67.198  ? 143 LEU A HD13 1 c 
ATOM   2196 H HD21 . LEU A 1 143 ? -40.499 -7.51   9.231   1 69.732  ? 143 LEU A HD21 1 c 
ATOM   2197 H HD22 . LEU A 1 143 ? -40.392 -6.475  8.033   1 69.772  ? 143 LEU A HD22 1 c 
ATOM   2198 H HD23 . LEU A 1 143 ? -39.356 -6.411  9.232   1 69.779  ? 143 LEU A HD23 1 c 
ATOM   2199 N N    . PHE A 1 144 ? -41.311 -10.732 5.006   1 60.559  ? 144 PHE A N    1 ? 
ATOM   2200 C CA   . PHE A 1 144 ? -42.003 -10.925 3.737   1 51.851  ? 144 PHE A CA   1 ? 
ATOM   2201 C C    . PHE A 1 144 ? -42.971 -12.097 3.792   1 52.047  ? 144 PHE A C    1 ? 
ATOM   2202 O O    . PHE A 1 144 ? -43.39  -12.589 2.741   1 55.312  ? 144 PHE A O    1 ? 
ATOM   2203 C CB   . PHE A 1 144 ? -41.007 -11.166 2.603   1 50.802  ? 144 PHE A CB   1 ? 
ATOM   2204 C CG   . PHE A 1 144 ? -40.272 -9.905  2.193   1 48.071  ? 144 PHE A CG   1 ? 
ATOM   2205 C CD1  . PHE A 1 144 ? -39.166 -9.469  2.905   1 44.9    ? 144 PHE A CD1  1 ? 
ATOM   2206 C CD2  . PHE A 1 144 ? -40.687 -9.165  1.087   1 49.347  ? 144 PHE A CD2  1 ? 
ATOM   2207 C CE1  . PHE A 1 144 ? -38.486 -8.317  2.53    1 45.312  ? 144 PHE A CE1  1 ? 
ATOM   2208 C CE2  . PHE A 1 144 ? -40     -8.024  0.709   1 49.954  ? 144 PHE A CE2  1 ? 
ATOM   2209 C CZ   . PHE A 1 144 ? -38.908 -7.593  1.44    1 48.254  ? 144 PHE A CZ   1 ? 
ATOM   2210 H H    . PHE A 1 144 ? -40.565 -11.232 5.176   1 59.546  ? 144 PHE A H    1 c 
ATOM   2211 H HA   . PHE A 1 144 ? -42.518 -10.102 3.526   1 53.367  ? 144 PHE A HA   1 c 
ATOM   2212 H HB2  . PHE A 1 144 ? -40.352 -11.84  2.893   1 50.459  ? 144 PHE A HB2  1 c 
ATOM   2213 H HB3  . PHE A 1 144 ? -41.485 -11.518 1.82    1 50.438  ? 144 PHE A HB3  1 c 
ATOM   2214 H HD1  . PHE A 1 144 ? -38.877 -9.955  3.656   1 45.889  ? 144 PHE A HD1  1 c 
ATOM   2215 H HD2  . PHE A 1 144 ? -41.433 -9.452  0.585   1 49.147  ? 144 PHE A HD2  1 c 
ATOM   2216 H HE1  . PHE A 1 144 ? -37.737 -8.029  3.029   1 45.96   ? 144 PHE A HE1  1 c 
ATOM   2217 H HE2  . PHE A 1 144 ? -40.292 -7.526  -0.038  1 49.349  ? 144 PHE A HE2  1 c 
ATOM   2218 H HZ   . PHE A 1 144 ? -38.444 -6.812  1.182   1 47.924  ? 144 PHE A HZ   1 c 
ATOM   2219 N N    . TYR A 1 145 ? -43.331 -12.548 4.997   1 55.3    ? 145 TYR A N    1 ? 
ATOM   2220 C CA   . TYR A 1 145 ? -44.345 -13.586 5.119   1 62.729  ? 145 TYR A CA   1 ? 
ATOM   2221 C C    . TYR A 1 145 ? -45.645 -13.087 4.478   1 55.539  ? 145 TYR A C    1 ? 
ATOM   2222 O O    . TYR A 1 145 ? -46.059 -11.977 4.774   1 58.57   ? 145 TYR A O    1 ? 
ATOM   2223 C CB   . TYR A 1 145 ? -44.579 -13.976 6.586   1 56.691  ? 145 TYR A CB   1 ? 
ATOM   2224 C CG   . TYR A 1 145 ? -45.648 -15.05  6.741   1 59.012  ? 145 TYR A CG   1 ? 
ATOM   2225 C CD1  . TYR A 1 145 ? -45.651 -16.2   5.943   1 61.529  ? 145 TYR A CD1  1 ? 
ATOM   2226 C CD2  . TYR A 1 145 ? -46.686 -14.91  7.659   1 63.318  ? 145 TYR A CD2  1 ? 
ATOM   2227 C CE1  . TYR A 1 145 ? -46.624 -17.183 6.076   1 62.712  ? 145 TYR A CE1  1 ? 
ATOM   2228 C CE2  . TYR A 1 145 ? -47.673 -15.885 7.795   1 65.84   ? 145 TYR A CE2  1 ? 
ATOM   2229 C CZ   . TYR A 1 145 ? -47.646 -17.027 7.006   1 66.479  ? 145 TYR A CZ   1 ? 
ATOM   2230 O OH   . TYR A 1 145 ? -48.632 -17.974 7.15    1 60.613  ? 145 TYR A OH   1 ? 
ATOM   2231 H H    . TYR A 1 145 ? -42.945 -12.221 5.756   1 56.157  ? 145 TYR A H    1 c 
ATOM   2232 H HA   . TYR A 1 145 ? -44.027 -14.384 4.624   1 58.791  ? 145 TYR A HA   1 c 
ATOM   2233 H HB2  . TYR A 1 145 ? -43.733 -14.306 6.964   1 58.545  ? 145 TYR A HB2  1 c 
ATOM   2234 H HB3  . TYR A 1 145 ? -44.85  -13.174 7.087   1 58.587  ? 145 TYR A HB3  1 c 
ATOM   2235 H HD1  . TYR A 1 145 ? -44.96  -16.326 5.313   1 61.242  ? 145 TYR A HD1  1 c 
ATOM   2236 H HD2  . TYR A 1 145 ? -46.72  -14.142 8.206   1 62.807  ? 145 TYR A HD2  1 c 
ATOM   2237 H HE1  . TYR A 1 145 ? -46.594 -17.948 5.532   1 63.475  ? 145 TYR A HE1  1 c 
ATOM   2238 H HE2  . TYR A 1 145 ? -48.362 -15.771 8.428   1 65.261  ? 145 TYR A HE2  1 c 
ATOM   2239 N N    . GLN A 1 146 ? -46.258 -13.916 3.616   1 60.918  ? 146 GLN A N    1 ? 
ATOM   2240 C CA   . GLN A 1 146 ? -47.466 -13.606 2.857   1 54.682  ? 146 GLN A CA   1 ? 
ATOM   2241 C C    . GLN A 1 146 ? -48.377 -14.834 2.819   1 55.827  ? 146 GLN A C    1 ? 
ATOM   2242 O O    . GLN A 1 146 ? -48.291 -15.647 1.897   1 56.46   ? 146 GLN A O    1 ? 
ATOM   2243 C CB   . GLN A 1 146 ? -47.123 -13.19  1.425   1 53.947  ? 146 GLN A CB   1 ? 
ATOM   2244 C CG   . GLN A 1 146 ? -46.325 -11.893 1.346   1 54.174  ? 146 GLN A CG   1 ? 
ATOM   2245 C CD   . GLN A 1 146 ? -45.621 -11.71  0.02    1 57.872  ? 146 GLN A CD   1 ? 
ATOM   2246 O OE1  . GLN A 1 146 ? -46.257 -11.551 -1.03   1 59.764  ? 146 GLN A OE1  1 ? 
ATOM   2247 N NE2  . GLN A 1 146 ? -44.296 -11.72  0.057   1 54.103  ? 146 GLN A NE2  1 ? 
ATOM   2248 H H    . GLN A 1 146 ? -45.889 -14.743 3.492   1 58.142  ? 146 GLN A H    1 c 
ATOM   2249 H HA   . GLN A 1 146 ? -47.936 -12.855 3.292   1 56.025  ? 146 GLN A HA   1 c 
ATOM   2250 H HB2  . GLN A 1 146 ? -46.603 -13.907 1.005   1 54.211  ? 146 GLN A HB2  1 c 
ATOM   2251 H HB3  . GLN A 1 146 ? -47.954 -13.088 0.916   1 54.246  ? 146 GLN A HB3  1 c 
ATOM   2252 H HG2  . GLN A 1 146 ? -46.933 -11.139 1.482   1 55.015  ? 146 GLN A HG2  1 c 
ATOM   2253 H HG3  . GLN A 1 146 ? -45.664 -11.87  2.061   1 54.994  ? 146 GLN A HG3  1 c 
ATOM   2254 H HE21 . GLN A 1 146 ? -43.842 -12.223 -0.515  1 55.191  ? 146 GLN A HE21 1 c 
ATOM   2255 H HE22 . GLN A 1 146 ? -43.865 -11.222 0.651   1 55.223  ? 146 GLN A HE22 1 c 
ATOM   2256 N N    . PRO A 1 147 ? -49.269 -15.023 3.822   1 63.89   ? 147 PRO A N    1 ? 
ATOM   2257 C CA   . PRO A 1 147 ? -50.075 -16.245 3.907   1 64.784  ? 147 PRO A CA   1 ? 
ATOM   2258 C C    . PRO A 1 147 ? -50.929 -16.549 2.676   1 68.112  ? 147 PRO A C    1 ? 
ATOM   2259 O O    . PRO A 1 147 ? -51.187 -17.709 2.362   1 64.901  ? 147 PRO A O    1 ? 
ATOM   2260 C CB   . PRO A 1 147 ? -50.92  -16.066 5.17    1 68.181  ? 147 PRO A CB   1 ? 
ATOM   2261 C CG   . PRO A 1 147 ? -50.666 -14.643 5.661   1 68.935  ? 147 PRO A CG   1 ? 
ATOM   2262 C CD   . PRO A 1 147 ? -49.452 -14.111 4.968   1 64.176  ? 147 PRO A CD   1 ? 
ATOM   2263 H HA   . PRO A 1 147 ? -49.47  -17.001 4.055   1 65.824  ? 147 PRO A HA   1 c 
ATOM   2264 H HB2  . PRO A 1 147 ? -51.869 -16.196 4.975   1 67.567  ? 147 PRO A HB2  1 c 
ATOM   2265 H HB3  . PRO A 1 147 ? -50.659 -16.715 5.852   1 67.533  ? 147 PRO A HB3  1 c 
ATOM   2266 H HG2  . PRO A 1 147 ? -51.438 -14.075 5.465   1 67.638  ? 147 PRO A HG2  1 c 
ATOM   2267 H HG3  . PRO A 1 147 ? -50.525 -14.641 6.629   1 67.638  ? 147 PRO A HG3  1 c 
ATOM   2268 H HD2  . PRO A 1 147 ? -49.602 -13.196 4.664   1 65.034  ? 147 PRO A HD2  1 c 
ATOM   2269 H HD3  . PRO A 1 147 ? -48.67  -14.132 5.554   1 65.132  ? 147 PRO A HD3  1 c 
ATOM   2270 N N    . LYS A 1 148 ? -51.364 -15.511 1.957   1 74.563  ? 148 LYS A N    1 ? 
ATOM   2271 C CA   . LYS A 1 148 ? -52.099 -15.731 0.72    1 77.72   ? 148 LYS A CA   1 ? 
ATOM   2272 C C    . LYS A 1 148 ? -51.279 -16.594 -0.244  1 69.788  ? 148 LYS A C    1 ? 
ATOM   2273 O O    . LYS A 1 148 ? -51.863 -17.345 -1.014  1 61.821  ? 148 LYS A O    1 ? 
ATOM   2274 C CB   . LYS A 1 148 ? -52.496 -14.39  0.095   1 80.609  ? 148 LYS A CB   1 ? 
ATOM   2275 C CG   . LYS A 1 148 ? -53.478 -14.454 -1.065  1 86.539  ? 148 LYS A CG   1 ? 
ATOM   2276 C CD   . LYS A 1 148 ? -53.857 -13.057 -1.542  1 92.586  ? 148 LYS A CD   1 ? 
ATOM   2277 C CE   . LYS A 1 148 ? -54.976 -13.029 -2.528  1 93.339  ? 148 LYS A CE   1 ? 
ATOM   2278 N NZ   . LYS A 1 148 ? -55.3   -11.642 -2.868  1 95.363  ? 148 LYS A NZ   1 ? 
ATOM   2279 H H    . LYS A 1 148 ? -51.22  -14.656 2.244   1 73.518  ? 148 LYS A H    1 c 
ATOM   2280 H HA   . LYS A 1 148 ? -52.93  -16.223 0.943   1 76.038  ? 148 LYS A HA   1 c 
ATOM   2281 H HB2  . LYS A 1 148 ? -52.89  -13.829 0.796   1 81.204  ? 148 LYS A HB2  1 c 
ATOM   2282 H HB3  . LYS A 1 148 ? -51.682 -13.942 -0.218  1 81.248  ? 148 LYS A HB3  1 c 
ATOM   2283 H HG2  . LYS A 1 148 ? -53.069 -14.953 -1.805  1 86.379  ? 148 LYS A HG2  1 c 
ATOM   2284 H HG3  . LYS A 1 148 ? -54.286 -14.932 -0.775  1 86.444  ? 148 LYS A HG3  1 c 
ATOM   2285 H HD2  . LYS A 1 148 ? -54.109 -12.516 -0.762  1 91.304  ? 148 LYS A HD2  1 c 
ATOM   2286 H HD3  . LYS A 1 148 ? -53.067 -12.639 -1.948  1 91.343  ? 148 LYS A HD3  1 c 
ATOM   2287 H HE2  . LYS A 1 148 ? -54.719 -13.508 -3.337  1 93.639  ? 148 LYS A HE2  1 c 
ATOM   2288 H HE3  . LYS A 1 148 ? -55.764 -13.46  -2.15   1 93.639  ? 148 LYS A HE3  1 c 
ATOM   2289 H HZ1  . LYS A 1 148 ? -54.571 -11.232 -3.217  1 94.715  ? 148 LYS A HZ1  1 c 
ATOM   2290 H HZ2  . LYS A 1 148 ? -55.565 -11.197 -2.125  1 94.697  ? 148 LYS A HZ2  1 c 
ATOM   2291 H HZ3  . LYS A 1 148 ? -55.97  -11.626 -3.479  1 94.724  ? 148 LYS A HZ3  1 c 
ATOM   2292 N N    . PHE A 1 149 ? -49.939 -16.492 -0.191  1 73.582  ? 149 PHE A N    1 ? 
ATOM   2293 C CA   . PHE A 1 149 ? -49.071 -17.199 -1.124  1 73.396  ? 149 PHE A CA   1 ? 
ATOM   2294 C C    . PHE A 1 149 ? -48.238 -18.27  -0.409  1 76.71   ? 149 PHE A C    1 ? 
ATOM   2295 O O    . PHE A 1 149 ? -47.158 -18.632 -0.885  1 76.328  ? 149 PHE A O    1 ? 
ATOM   2296 C CB   . PHE A 1 149 ? -48.216 -16.161 -1.861  1 67.001  ? 149 PHE A CB   1 ? 
ATOM   2297 C CG   . PHE A 1 149 ? -49.001 -15.168 -2.704  1 66.019  ? 149 PHE A CG   1 ? 
ATOM   2298 C CD1  . PHE A 1 149 ? -49.411 -15.492 -3.996  1 72.392  ? 149 PHE A CD1  1 ? 
ATOM   2299 C CD2  . PHE A 1 149 ? -49.312 -13.903 -2.205  1 69.589  ? 149 PHE A CD2  1 ? 
ATOM   2300 C CE1  . PHE A 1 149 ? -50.137 -14.582 -4.759  1 69.969  ? 149 PHE A CE1  1 ? 
ATOM   2301 C CE2  . PHE A 1 149 ? -50.05  -13.002 -2.961  1 69.152  ? 149 PHE A CE2  1 ? 
ATOM   2302 C CZ   . PHE A 1 149 ? -50.441 -13.335 -4.246  1 66.743  ? 149 PHE A CZ   1 ? 
ATOM   2303 H H    . PHE A 1 149 ? -49.551 -15.933 0.418   1 72.539  ? 149 PHE A H    1 c 
ATOM   2304 H HA   . PHE A 1 149 ? -49.637 -17.656 -1.799  1 72.708  ? 149 PHE A HA   1 c 
ATOM   2305 H HB2  . PHE A 1 149 ? -47.69  -15.664 -1.196  1 68.188  ? 149 PHE A HB2  1 c 
ATOM   2306 H HB3  . PHE A 1 149 ? -47.584 -16.636 -2.445  1 68.214  ? 149 PHE A HB3  1 c 
ATOM   2307 H HD1  . PHE A 1 149 ? -49.203 -16.341 -4.352  1 70.25   ? 149 PHE A HD1  1 c 
ATOM   2308 H HD2  . PHE A 1 149 ? -49.05  -13.672 -1.328  1 68.652  ? 149 PHE A HD2  1 c 
ATOM   2309 H HE1  . PHE A 1 149 ? -50.409 -14.812 -5.633  1 69.713  ? 149 PHE A HE1  1 c 
ATOM   2310 H HE2  . PHE A 1 149 ? -50.257 -12.152 -2.612  1 68.566  ? 149 PHE A HE2  1 c 
ATOM   2311 H HZ   . PHE A 1 149 ? -50.934 -12.719 -4.763  1 68.075  ? 149 PHE A HZ   1 c 
ATOM   2312 N N    . GLU A 1 150 ? -48.765 -18.804 0.702   1 77.13   ? 150 GLU A N    1 ? 
ATOM   2313 C CA   . GLU A 1 150 ? -48.206 -19.969 1.374   1 81.105  ? 150 GLU A CA   1 ? 
ATOM   2314 C C    . GLU A 1 150 ? -48.032 -21.104 0.372   1 71.34   ? 150 GLU A C    1 ? 
ATOM   2315 O O    . GLU A 1 150 ? -48.994 -21.472 -0.3    1 66.5    ? 150 GLU A O    1 ? 
ATOM   2316 C CB   . GLU A 1 150 ? -49.154 -20.511 2.449   1 91.538  ? 150 GLU A CB   1 ? 
ATOM   2317 C CG   . GLU A 1 150 ? -48.562 -21.612 3.328   1 95.181  ? 150 GLU A CG   1 ? 
ATOM   2318 C CD   . GLU A 1 150 ? -47.83  -21.131 4.569   1 107.224 ? 150 GLU A CD   1 ? 
ATOM   2319 O OE1  . GLU A 1 150 ? -47.902 -19.929 4.929   1 106.385 ? 150 GLU A OE1  1 ? 
ATOM   2320 O OE2  . GLU A 1 150 ? -47.183 -21.997 5.194   1 117.633 ? 150 GLU A OE2  1 ? 
ATOM   2321 H H    . GLU A 1 150 ? -49.518 -18.43  1.058   1 77.918  ? 150 GLU A H    1 c 
ATOM   2322 H HA   . GLU A 1 150 ? -47.332 -19.724 1.771   1 80.011  ? 150 GLU A HA   1 c 
ATOM   2323 H HB2  . GLU A 1 150 ? -49.442 -19.765 3.015   1 89.884  ? 150 GLU A HB2  1 c 
ATOM   2324 H HB3  . GLU A 1 150 ? -49.956 -20.87  2.014   1 89.609  ? 150 GLU A HB3  1 c 
ATOM   2325 H HG2  . GLU A 1 150 ? -49.286 -22.209 3.612   1 96.935  ? 150 GLU A HG2  1 c 
ATOM   2326 H HG3  . GLU A 1 150 ? -47.939 -22.149 2.796   1 96.813  ? 150 GLU A HG3  1 c 
ATOM   2327 N N    . GLY A 1 151 ? -46.807 -21.643 0.298   1 67.915  ? 151 GLY A N    1 ? 
ATOM   2328 C CA   . GLY A 1 151 ? -46.486 -22.763 -0.574  1 62.609  ? 151 GLY A CA   1 ? 
ATOM   2329 C C    . GLY A 1 151 ? -46.169 -22.317 -2.001  1 65.124  ? 151 GLY A C    1 ? 
ATOM   2330 O O    . GLY A 1 151 ? -46.093 -23.165 -2.886  1 62.71   ? 151 GLY A O    1 ? 
ATOM   2331 H H    . GLY A 1 151 ? -46.139 -21.297 0.817   1 67.649  ? 151 GLY A H    1 c 
ATOM   2332 H HA2  . GLY A 1 151 ? -45.709 -23.242 -0.203  1 64.407  ? 151 GLY A HA2  1 c 
ATOM   2333 H HA3  . GLY A 1 151 ? -47.247 -23.391 -0.588  1 64.442  ? 151 GLY A HA3  1 c 
ATOM   2334 N N    . LYS A 1 152 ? -46.034 -20.995 -2.225  1 61.476  ? 152 LYS A N    1 ? 
ATOM   2335 C CA   . LYS A 1 152 ? -45.628 -20.451 -3.516  1 60.008  ? 152 LYS A CA   1 ? 
ATOM   2336 C C    . LYS A 1 152 ? -44.673 -19.264 -3.345  1 48.501  ? 152 LYS A C    1 ? 
ATOM   2337 O O    . LYS A 1 152 ? -44.276 -18.677 -4.336  1 47.648  ? 152 LYS A O    1 ? 
ATOM   2338 C CB   . LYS A 1 152 ? -46.836 -19.998 -4.354  1 66.231  ? 152 LYS A CB   1 ? 
ATOM   2339 C CG   . LYS A 1 152 ? -47.944 -21.03  -4.622  1 72.25   ? 152 LYS A CG   1 ? 
ATOM   2340 C CD   . LYS A 1 152 ? -49.21  -20.491 -5.291  1 71.214  ? 152 LYS A CD   1 ? 
ATOM   2341 H H    . LYS A 1 152 ? -46.259 -20.408 -1.564  1 61.783  ? 152 LYS A H    1 c 
ATOM   2342 H HA   . LYS A 1 152 ? -45.151 -21.157 -4.021  1 59.075  ? 152 LYS A HA   1 c 
ATOM   2343 H HB2  . LYS A 1 152 ? -47.243 -19.227 -3.904  1 65.947  ? 152 LYS A HB2  1 c 
ATOM   2344 H HB3  . LYS A 1 152 ? -46.504 -19.685 -5.223  1 65.925  ? 152 LYS A HB3  1 c 
ATOM   2345 H HG2  . LYS A 1 152 ? -47.57  -21.741 -5.186  1 70.589  ? 152 LYS A HG2  1 c 
ATOM   2346 H HG3  . LYS A 1 152 ? -48.196 -21.439 -3.767  1 70.528  ? 152 LYS A HG3  1 c 
ATOM   2347 N N    . GLN A 1 153 ? -44.254 -18.929 -2.12   1 50.344  ? 153 GLN A N    1 ? 
ATOM   2348 C CA   . GLN A 1 153 ? -43.396 -17.774 -1.908  1 52.972  ? 153 GLN A CA   1 ? 
ATOM   2349 C C    . GLN A 1 153 ? -42.019 -18.088 -2.483  1 58.219  ? 153 GLN A C    1 ? 
ATOM   2350 O O    . GLN A 1 153 ? -41.636 -19.255 -2.574  1 55.675  ? 153 GLN A O    1 ? 
ATOM   2351 C CB   . GLN A 1 153 ? -43.257 -17.367 -0.439  1 50.9    ? 153 GLN A CB   1 ? 
ATOM   2352 C CG   . GLN A 1 153 ? -44.525 -16.748 0.148   1 52.897  ? 153 GLN A CG   1 ? 
ATOM   2353 C CD   . GLN A 1 153 ? -44.275 -15.811 1.313   1 50.081  ? 153 GLN A CD   1 ? 
ATOM   2354 O OE1  . GLN A 1 153 ? -44.759 -16.033 2.429   1 50.408  ? 153 GLN A OE1  1 ? 
ATOM   2355 N NE2  . GLN A 1 153 ? -43.501 -14.762 1.068   1 49.894  ? 153 GLN A NE2  1 ? 
ATOM   2356 H H    . GLN A 1 153 ? -44.472 -19.443 -1.398  1 50.663  ? 153 GLN A H    1 c 
ATOM   2357 H HA   . GLN A 1 153 ? -43.779 -17.007 -2.407  1 52.883  ? 153 GLN A HA   1 c 
ATOM   2358 H HB2  . GLN A 1 153 ? -43.015 -18.157 0.086   1 51.859  ? 153 GLN A HB2  1 c 
ATOM   2359 H HB3  . GLN A 1 153 ? -42.522 -16.724 -0.362  1 51.837  ? 153 GLN A HB3  1 c 
ATOM   2360 H HG2  . GLN A 1 153 ? -44.995 -16.25  -0.555  1 51.815  ? 153 GLN A HG2  1 c 
ATOM   2361 H HG3  . GLN A 1 153 ? -45.121 -17.466 0.45    1 51.88   ? 153 GLN A HG3  1 c 
ATOM   2362 H HE21 . GLN A 1 153 ? -43.057 -14.377 1.733   1 49.965  ? 153 GLN A HE21 1 c 
ATOM   2363 H HE22 . GLN A 1 153 ? -43.428 -14.445 0.243   1 50.011  ? 153 GLN A HE22 1 c 
ATOM   2364 N N    . ARG A 1 154 ? -41.297 -17.033 -2.872  1 46.654  ? 154 ARG A N    1 ? 
ATOM   2365 C CA   . ARG A 1 154 ? -39.988 -17.179 -3.473  1 42.729  ? 154 ARG A CA   1 ? 
ATOM   2366 C C    . ARG A 1 154 ? -39.09  -16.101 -2.892  1 48.148  ? 154 ARG A C    1 ? 
ATOM   2367 O O    . ARG A 1 154 ? -39.601 -15.119 -2.358  1 50.949  ? 154 ARG A O    1 ? 
ATOM   2368 C CB   . ARG A 1 154 ? -40.018 -17.086 -5.003  1 44.559  ? 154 ARG A CB   1 ? 
ATOM   2369 C CG   . ARG A 1 154 ? -40.997 -18.051 -5.665  1 49.258  ? 154 ARG A CG   1 ? 
ATOM   2370 C CD   . ARG A 1 154 ? -40.65  -18.351 -7.126  1 48.819  ? 154 ARG A CD   1 ? 
ATOM   2371 N NE   . ARG A 1 154 ? -40.735 -17.163 -7.991  1 52.973  ? 154 ARG A NE   1 ? 
ATOM   2372 C CZ   . ARG A 1 154 ? -41.788 -16.856 -8.753  1 50.918  ? 154 ARG A CZ   1 ? 
ATOM   2373 N NH1  . ARG A 1 154 ? -42.929 -17.507 -8.622  1 47.459  ? 154 ARG A NH1  1 ? 
ATOM   2374 N NH2  . ARG A 1 154 ? -41.727 -15.861 -9.607  1 53.937  ? 154 ARG A NH2  1 ? 
ATOM   2375 H H    . ARG A 1 154 ? -41.637 -16.192 -2.759  1 48.285  ? 154 ARG A H    1 c 
ATOM   2376 H HA   . ARG A 1 154 ? -39.621 -18.057 -3.217  1 44.947  ? 154 ARG A HA   1 c 
ATOM   2377 H HB2  . ARG A 1 154 ? -40.258 -16.17  -5.258  1 45.178  ? 154 ARG A HB2  1 c 
ATOM   2378 H HB3  . ARG A 1 154 ? -39.117 -17.266 -5.347  1 45.181  ? 154 ARG A HB3  1 c 
ATOM   2379 H HG2  . ARG A 1 154 ? -41.012 -18.892 -5.162  1 48.123  ? 154 ARG A HG2  1 c 
ATOM   2380 H HG3  . ARG A 1 154 ? -41.9   -17.666 -5.627  1 48.063  ? 154 ARG A HG3  1 c 
ATOM   2381 H HD2  . ARG A 1 154 ? -39.738 -18.707 -7.163  1 49.867  ? 154 ARG A HD2  1 c 
ATOM   2382 H HD3  . ARG A 1 154 ? -41.251 -19.046 -7.463  1 49.858  ? 154 ARG A HD3  1 c 
ATOM   2383 H HE   . ARG A 1 154 ? -40.06  -16.615 -7.997  1 51.464  ? 154 ARG A HE   1 c 
ATOM   2384 H HH11 . ARG A 1 154 ? -43.339 -17.522 -7.839  1 48.521  ? 154 ARG A HH11 1 c 
ATOM   2385 H HH12 . ARG A 1 154 ? -43.279 -17.924 -9.319  1 48.597  ? 154 ARG A HH12 1 c 
ATOM   2386 H HH21 . ARG A 1 154 ? -40.953 -15.643 -9.975  1 52.956  ? 154 ARG A HH21 1 c 
ATOM   2387 H HH22 . ARG A 1 154 ? -42.461 -15.416 -9.814  1 52.896  ? 154 ARG A HH22 1 c 
ATOM   2388 N N    . ILE A 1 155 ? -37.766 -16.283 -3.035  1 46.108  ? 155 ILE A N    1 ? 
ATOM   2389 C CA   . ILE A 1 155 ? -36.795 -15.279 -2.634  1 44.529  ? 155 ILE A CA   1 ? 
ATOM   2390 C C    . ILE A 1 155 ? -35.573 -15.372 -3.552  1 47.973  ? 155 ILE A C    1 ? 
ATOM   2391 O O    . ILE A 1 155 ? -35.056 -16.458 -3.808  1 44.617  ? 155 ILE A O    1 ? 
ATOM   2392 C CB   . ILE A 1 155 ? -36.457 -15.443 -1.136  1 47.554  ? 155 ILE A CB   1 ? 
ATOM   2393 C CG1  . ILE A 1 155 ? -35.441 -14.435 -0.659  1 51.861  ? 155 ILE A CG1  1 ? 
ATOM   2394 C CG2  . ILE A 1 155 ? -36.013 -16.868 -0.798  1 51.577  ? 155 ILE A CG2  1 ? 
ATOM   2395 C CD1  . ILE A 1 155 ? -35.291 -14.388 0.851   1 58.471  ? 155 ILE A CD1  1 ? 
ATOM   2396 H H    . ILE A 1 155 ? -37.462 -17.068 -3.392  1 46.198  ? 155 ILE A H    1 c 
ATOM   2397 H HA   . ILE A 1 155 ? -37.201 -14.399 -2.755  1 46.027  ? 155 ILE A HA   1 c 
ATOM   2398 H HB   . ILE A 1 155 ? -37.278 -15.269 -0.64   1 48.646  ? 155 ILE A HB   1 c 
ATOM   2399 H HG12 . ILE A 1 155 ? -34.571 -14.651 -1.052  1 52.225  ? 155 ILE A HG12 1 c 
ATOM   2400 H HG13 . ILE A 1 155 ? -35.702 -13.548 -0.977  1 52.209  ? 155 ILE A HG13 1 c 
ATOM   2401 H HG21 . ILE A 1 155 ? -35.976 -16.979 0.167   1 50.385  ? 155 ILE A HG21 1 c 
ATOM   2402 H HG22 . ILE A 1 155 ? -35.132 -17.033 -1.173  1 50.323  ? 155 ILE A HG22 1 c 
ATOM   2403 H HG23 . ILE A 1 155 ? -36.644 -17.507 -1.167  1 50.336  ? 155 ILE A HG23 1 c 
ATOM   2404 H HD11 . ILE A 1 155 ? -36.171 -14.423 1.271   1 56.374  ? 155 ILE A HD11 1 c 
ATOM   2405 H HD12 . ILE A 1 155 ? -34.843 -13.56  1.107   1 56.416  ? 155 ILE A HD12 1 c 
ATOM   2406 H HD13 . ILE A 1 155 ? -34.759 -15.149 1.151   1 56.399  ? 155 ILE A HD13 1 c 
ATOM   2407 N N    . VAL A 1 156 ? -35.124 -14.218 -4.062  1 44.471  ? 156 VAL A N    1 ? 
ATOM   2408 C CA   . VAL A 1 156 ? -33.904 -14.148 -4.834  1 47.703  ? 156 VAL A CA   1 ? 
ATOM   2409 C C    . VAL A 1 156 ? -32.771 -13.991 -3.829  1 53.372  ? 156 VAL A C    1 ? 
ATOM   2410 O O    . VAL A 1 156 ? -32.837 -13.112 -2.966  1 53.103  ? 156 VAL A O    1 ? 
ATOM   2411 C CB   . VAL A 1 156 ? -33.969 -12.986 -5.838  1 44.103  ? 156 VAL A CB   1 ? 
ATOM   2412 C CG1  . VAL A 1 156 ? -32.653 -12.742 -6.566  1 44.492  ? 156 VAL A CG1  1 ? 
ATOM   2413 C CG2  . VAL A 1 156 ? -35.117 -13.16  -6.825  1 48.302  ? 156 VAL A CG2  1 ? 
ATOM   2414 H H    . VAL A 1 156 ? -35.596 -13.448 -3.919  1 45.982  ? 156 VAL A H    1 c 
ATOM   2415 H HA   . VAL A 1 156 ? -33.788 -14.981 -5.326  1 47.366  ? 156 VAL A HA   1 c 
ATOM   2416 H HB   . VAL A 1 156 ? -34.159 -12.177 -5.318  1 45.608  ? 156 VAL A HB   1 c 
ATOM   2417 H HG11 . VAL A 1 156 ? -32.266 -13.594 -6.831  1 44.436  ? 156 VAL A HG11 1 c 
ATOM   2418 H HG12 . VAL A 1 156 ? -32.035 -12.278 -5.976  1 44.436  ? 156 VAL A HG12 1 c 
ATOM   2419 H HG13 . VAL A 1 156 ? -32.808 -12.199 -7.356  1 44.437  ? 156 VAL A HG13 1 c 
ATOM   2420 H HG21 . VAL A 1 156 ? -34.995 -12.563 -7.578  1 46.963  ? 156 VAL A HG21 1 c 
ATOM   2421 H HG22 . VAL A 1 156 ? -35.958 -12.954 -6.384  1 47.01   ? 156 VAL A HG22 1 c 
ATOM   2422 H HG23 . VAL A 1 156 ? -35.135 -14.079 -7.142  1 47.01   ? 156 VAL A HG23 1 c 
ATOM   2423 N N    . LEU A 1 157 ? -31.756 -14.858 -3.95   1 53.237  ? 157 LEU A N    1 ? 
ATOM   2424 C CA   . LEU A 1 157 ? -30.609 -14.851 -3.055  1 49.904  ? 157 LEU A CA   1 ? 
ATOM   2425 C C    . LEU A 1 157 ? -29.382 -14.288 -3.751  1 48.434  ? 157 LEU A C    1 ? 
ATOM   2426 O O    . LEU A 1 157 ? -28.316 -14.208 -3.148  1 48.406  ? 157 LEU A O    1 ? 
ATOM   2427 C CB   . LEU A 1 157 ? -30.409 -16.266 -2.53   1 44.679  ? 157 LEU A CB   1 ? 
ATOM   2428 C CG   . LEU A 1 157 ? -31.536 -16.749 -1.617  1 44.609  ? 157 LEU A CG   1 ? 
ATOM   2429 C CD1  . LEU A 1 157 ? -31.361 -18.193 -1.242  1 48.223  ? 157 LEU A CD1  1 ? 
ATOM   2430 C CD2  . LEU A 1 157 ? -31.646 -15.885 -0.363  1 46.337  ? 157 LEU A CD2  1 ? 
ATOM   2431 H H    . LEU A 1 157 ? -31.787 -15.492 -4.608  1 52.347  ? 157 LEU A H    1 c 
ATOM   2432 H HA   . LEU A 1 157 ? -30.812 -14.258 -2.293  1 49.266  ? 157 LEU A HA   1 c 
ATOM   2433 H HB2  . LEU A 1 157 ? -30.341 -16.878 -3.299  1 45.876  ? 157 LEU A HB2  1 c 
ATOM   2434 H HB3  . LEU A 1 157 ? -29.563 -16.294 -2.029  1 45.924  ? 157 LEU A HB3  1 c 
ATOM   2435 H HG   . LEU A 1 157 ? -32.39  -16.67  -2.114  1 45.641  ? 157 LEU A HG   1 c 
ATOM   2436 H HD11 . LEU A 1 157 ? -31.215 -18.722 -2.044  1 47.112  ? 157 LEU A HD11 1 c 
ATOM   2437 H HD12 . LEU A 1 157 ? -32.159 -18.51  -0.787  1 47.118  ? 157 LEU A HD12 1 c 
ATOM   2438 H HD13 . LEU A 1 157 ? -30.595 -18.285 -0.651  1 47.137  ? 157 LEU A HD13 1 c 
ATOM   2439 H HD21 . LEU A 1 157 ? -32.169 -15.09  -0.561  1 45.848  ? 157 LEU A HD21 1 c 
ATOM   2440 H HD22 . LEU A 1 157 ? -30.758 -15.622 -0.069  1 45.825  ? 157 LEU A HD22 1 c 
ATOM   2441 H HD23 . LEU A 1 157 ? -32.083 -16.39  0.344   1 45.841  ? 157 LEU A HD23 1 c 
ATOM   2442 N N    . GLY A 1 158 ? -29.563 -13.815 -4.984  1 50.847  ? 158 GLY A N    1 ? 
ATOM   2443 C CA   . GLY A 1 158 ? -28.5   -13.149 -5.714  1 53.186  ? 158 GLY A CA   1 ? 
ATOM   2444 C C    . GLY A 1 158 ? -27.638 -14.147 -6.483  1 47.485  ? 158 GLY A C    1 ? 
ATOM   2445 O O    . GLY A 1 158 ? -28.139 -14.833 -7.359  1 44.682  ? 158 GLY A O    1 ? 
ATOM   2446 H H    . GLY A 1 158 ? -30.37  -13.913 -5.399  1 50.735  ? 158 GLY A H    1 c 
ATOM   2447 H HA2  . GLY A 1 158 ? -28.9   -12.512 -6.347  1 51.302  ? 158 GLY A HA2  1 c 
ATOM   2448 H HA3  . GLY A 1 158 ? -27.941 -12.636 -5.086  1 51.267  ? 158 GLY A HA3  1 c 
ATOM   2449 N N    . GLY A 1 159 ? -26.339 -14.176 -6.164  1 47.203  ? 159 GLY A N    1 ? 
ATOM   2450 C CA   . GLY A 1 159 ? -25.387 -15.051 -6.819  1 48.33   ? 159 GLY A CA   1 ? 
ATOM   2451 C C    . GLY A 1 159 ? -24.823 -14.443 -8.1    1 49.959  ? 159 GLY A C    1 ? 
ATOM   2452 O O    . GLY A 1 159 ? -24.134 -15.126 -8.847  1 51.953  ? 159 GLY A O    1 ? 
ATOM   2453 H H    . GLY A 1 159 ? -26.031 -13.623 -5.505  1 47.593  ? 159 GLY A H    1 c 
ATOM   2454 H HA2  . GLY A 1 159 ? -24.647 -15.237 -6.195  1 48.41   ? 159 GLY A HA2  1 c 
ATOM   2455 H HA3  . GLY A 1 159 ? -25.824 -15.91  -7.029  1 48.388  ? 159 GLY A HA3  1 c 
ATOM   2456 N N    . ASP A 1 160 ? -25.115 -13.163 -8.357  1 47.775  ? 160 ASP A N    1 ? 
ATOM   2457 C CA   . ASP A 1 160 ? -24.668 -12.533 -9.586  1 49.051  ? 160 ASP A CA   1 ? 
ATOM   2458 C C    . ASP A 1 160 ? -23.317 -11.886 -9.328  1 47.817  ? 160 ASP A C    1 ? 
ATOM   2459 O O    . ASP A 1 160 ? -23.118 -11.349 -8.244  1 49.41   ? 160 ASP A O    1 ? 
ATOM   2460 C CB   . ASP A 1 160 ? -25.686 -11.528 -10.1   1 52.689  ? 160 ASP A CB   1 ? 
ATOM   2461 C CG   . ASP A 1 160 ? -25.975 -10.361 -9.166  1 56.064  ? 160 ASP A CG   1 ? 
ATOM   2462 O OD1  . ASP A 1 160 ? -26.344 -10.614 -7.993  1 48.551  ? 160 ASP A OD1  1 ? 
ATOM   2463 O OD2  . ASP A 1 160 ? -25.797 -9.212  -9.615  1 53.79   ? 160 ASP A OD2  1 ? 
ATOM   2464 H H    . ASP A 1 160 ? -25.576 -12.664 -7.748  1 48.596  ? 160 ASP A H    1 c 
ATOM   2465 H HA   . ASP A 1 160 ? -24.565 -13.224 -10.266 1 49.246  ? 160 ASP A HA   1 c 
ATOM   2466 H HB2  . ASP A 1 160 ? -25.353 -11.164 -10.947 1 52.577  ? 160 ASP A HB2  1 c 
ATOM   2467 H HB3  . ASP A 1 160 ? -26.518 -11.987 -10.289 1 52.552  ? 160 ASP A HB3  1 c 
ATOM   2468 N N    . GLU A 1 161 ? -22.413 -12.001 -10.314 1 48.548  ? 161 GLU A N    1 ? 
ATOM   2469 C CA   . GLU A 1 161 ? -21.142 -11.29  -10.415 1 55.032  ? 161 GLU A CA   1 ? 
ATOM   2470 C C    . GLU A 1 161 ? -20.242 -11.567 -9.214  1 56.49   ? 161 GLU A C    1 ? 
ATOM   2471 O O    . GLU A 1 161 ? -19.631 -10.653 -8.656  1 55.926  ? 161 GLU A O    1 ? 
ATOM   2472 C CB   . GLU A 1 161 ? -21.329 -9.787  -10.625 1 57.45   ? 161 GLU A CB   1 ? 
ATOM   2473 C CG   . GLU A 1 161 ? -22.275 -9.472  -11.78  1 62.208  ? 161 GLU A CG   1 ? 
ATOM   2474 C CD   . GLU A 1 161 ? -22.506 -8      -12.043 1 56.948  ? 161 GLU A CD   1 ? 
ATOM   2475 O OE1  . GLU A 1 161 ? -22.598 -7.19   -11.079 1 55.76   ? 161 GLU A OE1  1 ? 
ATOM   2476 O OE2  . GLU A 1 161 ? -22.605 -7.702  -13.25  1 54.356  ? 161 GLU A OE2  1 ? 
ATOM   2477 H H    . GLU A 1 161 ? -22.604 -12.591 -10.984 1 49.753  ? 161 GLU A H    1 c 
ATOM   2478 H HA   . GLU A 1 161 ? -20.677 -11.634 -11.22  1 54.398  ? 161 GLU A HA   1 c 
ATOM   2479 H HB2  . GLU A 1 161 ? -21.682 -9.391  -9.801  1 57.906  ? 161 GLU A HB2  1 c 
ATOM   2480 H HB3  . GLU A 1 161 ? -20.457 -9.379  -10.806 1 57.917  ? 161 GLU A HB3  1 c 
ATOM   2481 H HG2  . GLU A 1 161 ? -21.92  -9.881  -12.598 1 59.812  ? 161 GLU A HG2  1 c 
ATOM   2482 H HG3  . GLU A 1 161 ? -23.144 -9.888  -11.602 1 59.784  ? 161 GLU A HG3  1 c 
ATOM   2483 N N    . VAL A 1 162 ? -20.134 -12.845 -8.853  1 53.098  ? 162 VAL A N    1 ? 
ATOM   2484 C CA   . VAL A 1 162 ? -19.461 -13.229 -7.625  1 52.405  ? 162 VAL A CA   1 ? 
ATOM   2485 C C    . VAL A 1 162 ? -17.981 -13.364 -7.931  1 48.855  ? 162 VAL A C    1 ? 
ATOM   2486 O O    . VAL A 1 162 ? -17.576 -14.273 -8.66   1 45.939  ? 162 VAL A O    1 ? 
ATOM   2487 C CB   . VAL A 1 162 ? -20.04  -14.524 -7.052  1 52.755  ? 162 VAL A CB   1 ? 
ATOM   2488 C CG1  . VAL A 1 162 ? -19.325 -14.937 -5.776  1 53.349  ? 162 VAL A CG1  1 ? 
ATOM   2489 C CG2  . VAL A 1 162 ? -21.532 -14.373 -6.815  1 55.104  ? 162 VAL A CG2  1 ? 
ATOM   2490 H H    . VAL A 1 162 ? -20.477 -13.5   -9.39   1 53.696  ? 162 VAL A H    1 c 
ATOM   2491 H HA   . VAL A 1 162 ? -19.588 -12.521 -6.963  1 51.956  ? 162 VAL A HA   1 c 
ATOM   2492 H HB   . VAL A 1 162 ? -19.908 -15.229 -7.727  1 53.131  ? 162 VAL A HB   1 c 
ATOM   2493 H HG11 . VAL A 1 162 ? -19.38  -14.215 -5.127  1 53.158  ? 162 VAL A HG11 1 c 
ATOM   2494 H HG12 . VAL A 1 162 ? -18.392 -15.129 -5.964  1 53.104  ? 162 VAL A HG12 1 c 
ATOM   2495 H HG13 . VAL A 1 162 ? -19.748 -15.731 -5.409  1 53.164  ? 162 VAL A HG13 1 c 
ATOM   2496 H HG21 . VAL A 1 162 ? -21.85  -15.101 -6.265  1 54.342  ? 162 VAL A HG21 1 c 
ATOM   2497 H HG22 . VAL A 1 162 ? -21.995 -14.385 -7.667  1 54.333  ? 162 VAL A HG22 1 c 
ATOM   2498 H HG23 . VAL A 1 162 ? -21.705 -13.529 -6.366  1 54.32   ? 162 VAL A HG23 1 c 
ATOM   2499 N N    . SER A 1 163 ? -17.196 -12.418 -7.405  1 49.905  ? 163 SER A N    1 ? 
ATOM   2500 C CA   . SER A 1 163 ? -15.759 -12.444 -7.623  1 56.358  ? 163 SER A CA   1 ? 
ATOM   2501 C C    . SER A 1 163 ? -15.212 -13.733 -7.015  1 54.753  ? 163 SER A C    1 ? 
ATOM   2502 O O    . SER A 1 163 ? -15.669 -14.175 -5.95   1 50.579  ? 163 SER A O    1 ? 
ATOM   2503 C CB   . SER A 1 163 ? -15.06  -11.222 -7.071  1 56.277  ? 163 SER A CB   1 ? 
ATOM   2504 O OG   . SER A 1 163 ? -15.211 -11.166 -5.662  1 55.556  ? 163 SER A OG   1 ? 
ATOM   2505 H H    . SER A 1 163 ? -17.556 -11.744 -6.904  1 51.082  ? 163 SER A H    1 c 
ATOM   2506 H HA   . SER A 1 163 ? -15.605 -12.469 -8.602  1 54.699  ? 163 SER A HA   1 c 
ATOM   2507 H HB2  . SER A 1 163 ? -14.111 -11.26  -7.297  1 56.123  ? 163 SER A HB2  1 c 
ATOM   2508 H HB3  . SER A 1 163 ? -15.442 -10.419 -7.473  1 56.123  ? 163 SER A HB3  1 c 
ATOM   2509 N N    . GLY A 1 164 ? -14.292 -14.346 -7.77   1 59.305  ? 164 GLY A N    1 ? 
ATOM   2510 C CA   . GLY A 1 164 ? -13.613 -15.567 -7.383  1 54.37   ? 164 GLY A CA   1 ? 
ATOM   2511 C C    . GLY A 1 164 ? -14.42  -16.822 -7.696  1 55.074  ? 164 GLY A C    1 ? 
ATOM   2512 O O    . GLY A 1 164 ? -13.884 -17.92  -7.597  1 61.219  ? 164 GLY A O    1 ? 
ATOM   2513 H H    . GLY A 1 164 ? -14.072 -13.977 -8.577  1 57.021  ? 164 GLY A H    1 c 
ATOM   2514 H HA2  . GLY A 1 164 ? -12.749 -15.612 -7.856  1 55.665  ? 164 GLY A HA2  1 c 
ATOM   2515 H HA3  . GLY A 1 164 ? -13.423 -15.535 -6.416  1 55.639  ? 164 GLY A HA3  1 c 
ATOM   2516 N N    . SER A 1 165 ? -15.69  -16.68  -8.092  1 50.178  ? 165 SER A N    1 ? 
ATOM   2517 C CA   . SER A 1 165 ? -16.59  -17.823 -8.125  1 49.425  ? 165 SER A CA   1 ? 
ATOM   2518 C C    . SER A 1 165 ? -16.262 -18.81  -9.248  1 48.574  ? 165 SER A C    1 ? 
ATOM   2519 O O    . SER A 1 165 ? -16.743 -19.934 -9.215  1 54.221  ? 165 SER A O    1 ? 
ATOM   2520 C CB   . SER A 1 165 ? -18.039 -17.382 -8.21   1 48.776  ? 165 SER A CB   1 ? 
ATOM   2521 O OG   . SER A 1 165 ? -18.309 -16.707 -9.429  1 42.128  ? 165 SER A OG   1 ? 
ATOM   2522 H H    . SER A 1 165 ? -15.998 -15.872 -8.387  1 51.193  ? 165 SER A H    1 c 
ATOM   2523 H HA   . SER A 1 165 ? -16.48  -18.308 -7.267  1 49.375  ? 165 SER A HA   1 c 
ATOM   2524 H HB2  . SER A 1 165 ? -18.618 -18.165 -8.139  1 47.26   ? 165 SER A HB2  1 c 
ATOM   2525 H HB3  . SER A 1 165 ? -18.236 -16.795 -7.464  1 47.347  ? 165 SER A HB3  1 c 
ATOM   2526 N N    . GLU A 1 166 ? -15.519 -18.405 -10.277 1 46.985  ? 166 GLU A N    1 ? 
ATOM   2527 C CA   . GLU A 1 166 ? -15.244 -19.306 -11.384 1 56.972  ? 166 GLU A CA   1 ? 
ATOM   2528 C C    . GLU A 1 166 ? -14.206 -20.344 -10.942 1 55.546  ? 166 GLU A C    1 ? 
ATOM   2529 O O    . GLU A 1 166 ? -14.414 -21.553 -11.114 1 48.861  ? 166 GLU A O    1 ? 
ATOM   2530 C CB   . GLU A 1 166 ? -14.797 -18.562 -12.646 1 54.23   ? 166 GLU A CB   1 ? 
ATOM   2531 C CG   . GLU A 1 166 ? -14.921 -19.429 -13.894 1 58.903  ? 166 GLU A CG   1 ? 
ATOM   2532 C CD   . GLU A 1 166 ? -14.323 -18.817 -15.138 1 62.235  ? 166 GLU A CD   1 ? 
ATOM   2533 O OE1  . GLU A 1 166 ? -14.609 -17.645 -15.44  1 69.23   ? 166 GLU A OE1  1 ? 
ATOM   2534 O OE2  . GLU A 1 166 ? -13.565 -19.529 -15.808 1 66.644  ? 166 GLU A OE2  1 ? 
ATOM   2535 H H    . GLU A 1 166 ? -15.191 -17.553 -10.308 1 49.528  ? 166 GLU A H    1 c 
ATOM   2536 H HA   . GLU A 1 166 ? -16.082 -19.785 -11.611 1 54.113  ? 166 GLU A HA   1 c 
ATOM   2537 H HB2  . GLU A 1 166 ? -15.344 -17.756 -12.751 1 55.886  ? 166 GLU A HB2  1 c 
ATOM   2538 H HB3  . GLU A 1 166 ? -13.865 -18.28  -12.539 1 55.92   ? 166 GLU A HB3  1 c 
ATOM   2539 H HG2  . GLU A 1 166 ? -14.483 -20.291 -13.731 1 58.584  ? 166 GLU A HG2  1 c 
ATOM   2540 H HG3  . GLU A 1 166 ? -15.871 -19.609 -14.063 1 58.555  ? 166 GLU A HG3  1 c 
ATOM   2541 N N    . VAL A 1 167 ? -13.099 -19.846 -10.374 1 53.672  ? 167 VAL A N    1 ? 
ATOM   2542 C CA   . VAL A 1 167 ? -12.041 -20.687 -9.824  1 57.17   ? 167 VAL A CA   1 ? 
ATOM   2543 C C    . VAL A 1 167 ? -12.543 -21.437 -8.585  1 51.784  ? 167 VAL A C    1 ? 
ATOM   2544 O O    . VAL A 1 167 ? -12.376 -22.647 -8.504  1 51.008  ? 167 VAL A O    1 ? 
ATOM   2545 C CB   . VAL A 1 167 ? -10.78  -19.85  -9.53   1 61.51   ? 167 VAL A CB   1 ? 
ATOM   2546 C CG1  . VAL A 1 167 ? -9.769  -20.601 -8.656  1 65.794  ? 167 VAL A CG1  1 ? 
ATOM   2547 C CG2  . VAL A 1 167 ? -10.136 -19.345 -10.826 1 57.075  ? 167 VAL A CG2  1 ? 
ATOM   2548 H H    . VAL A 1 167 ? -12.993 -18.939 -10.338 1 54.932  ? 167 VAL A H    1 c 
ATOM   2549 H HA   . VAL A 1 167 ? -11.807 -21.351 -10.503 1 56.125  ? 167 VAL A HA   1 c 
ATOM   2550 H HB   . VAL A 1 167 ? -11.073 -19.059 -9.02   1 60.56   ? 167 VAL A HB   1 c 
ATOM   2551 H HG11 . VAL A 1 167 ? -9.738  -21.536 -8.923  1 64.402  ? 167 VAL A HG11 1 c 
ATOM   2552 H HG12 . VAL A 1 167 ? -10.033 -20.538 -7.723  1 64.401  ? 167 VAL A HG12 1 c 
ATOM   2553 H HG13 . VAL A 1 167 ? -8.888  -20.206 -8.768  1 64.385  ? 167 VAL A HG13 1 c 
ATOM   2554 H HG21 . VAL A 1 167 ? -9.364  -18.795 -10.613 1 58.374  ? 167 VAL A HG21 1 c 
ATOM   2555 H HG22 . VAL A 1 167 ? -10.78  -18.817 -11.326 1 58.324  ? 167 VAL A HG22 1 c 
ATOM   2556 H HG23 . VAL A 1 167 ? -9.853  -20.103 -11.365 1 58.343  ? 167 VAL A HG23 1 c 
ATOM   2557 N N    . HIS A 1 168 ? -13.167 -20.722 -7.637  1 52.261  ? 168 HIS A N    1 ? 
ATOM   2558 C CA   . HIS A 1 168 ? -13.616 -21.295 -6.375  1 50.414  ? 168 HIS A CA   1 ? 
ATOM   2559 C C    . HIS A 1 168 ? -15.098 -21.673 -6.438  1 47.18   ? 168 HIS A C    1 ? 
ATOM   2560 O O    . HIS A 1 168 ? -15.857 -21.404 -5.505  1 45.706  ? 168 HIS A O    1 ? 
ATOM   2561 C CB   . HIS A 1 168 ? -13.303 -20.333 -5.224  1 51.579  ? 168 HIS A CB   1 ? 
ATOM   2562 C CG   . HIS A 1 168 ? -11.904 -19.822 -5.247  1 51.863  ? 168 HIS A CG   1 ? 
ATOM   2563 N ND1  . HIS A 1 168 ? -10.868 -20.548 -4.702  1 49.069  ? 168 HIS A ND1  1 ? 
ATOM   2564 C CD2  . HIS A 1 168 ? -11.359 -18.686 -5.718  1 57.34   ? 168 HIS A CD2  1 ? 
ATOM   2565 C CE1  . HIS A 1 168 ? -9.747  -19.873 -4.853  1 54.195  ? 168 HIS A CE1  1 ? 
ATOM   2566 N NE2  . HIS A 1 168 ? -10.008 -18.742 -5.474  1 59.967  ? 168 HIS A NE2  1 ? 
ATOM   2567 H H    . HIS A 1 168 ? -13.317 -19.833 -7.784  1 51.772  ? 168 HIS A H    1 c 
ATOM   2568 H HA   . HIS A 1 168 ? -13.104 -22.116 -6.215  1 50.378  ? 168 HIS A HA   1 c 
ATOM   2569 H HB2  . HIS A 1 168 ? -13.921 -19.571 -5.273  1 51.344  ? 168 HIS A HB2  1 c 
ATOM   2570 H HB3  . HIS A 1 168 ? -13.46  -20.797 -4.373  1 51.347  ? 168 HIS A HB3  1 c 
ATOM   2571 H HD2  . HIS A 1 168 ? -11.802 -17.982 -6.149  1 56.556  ? 168 HIS A HD2  1 c 
ATOM   2572 H HE1  . HIS A 1 168 ? -8.923  -20.16  -4.574  1 54.233  ? 168 HIS A HE1  1 c 
ATOM   2573 N N    . GLN A 1 169 ? -15.464 -22.394 -7.503  1 46.004  ? 169 GLN A N    1 ? 
ATOM   2574 C CA   . GLN A 1 169 ? -16.847 -22.663 -7.862  1 46.056  ? 169 GLN A CA   1 ? 
ATOM   2575 C C    . GLN A 1 169 ? -17.551 -23.475 -6.781  1 48.164  ? 169 GLN A C    1 ? 
ATOM   2576 O O    . GLN A 1 169 ? -18.706 -23.195 -6.474  1 51.484  ? 169 GLN A O    1 ? 
ATOM   2577 C CB   . GLN A 1 169 ? -16.909 -23.314 -9.243  1 44.365  ? 169 GLN A CB   1 ? 
ATOM   2578 C CG   . GLN A 1 169 ? -18.285 -23.842 -9.65   1 46.519  ? 169 GLN A CG   1 ? 
ATOM   2579 C CD   . GLN A 1 169 ? -19.303 -22.792 -10.052 1 43.38   ? 169 GLN A CD   1 ? 
ATOM   2580 O OE1  . GLN A 1 169 ? -20.474 -23.121 -10.226 1 41.719  ? 169 GLN A OE1  1 ? 
ATOM   2581 N NE2  . GLN A 1 169 ? -18.896 -21.543 -10.236 1 42.54   ? 169 GLN A NE2  1 ? 
ATOM   2582 H H    . GLN A 1 169 ? -14.809 -22.766 -8.019  1 46.362  ? 169 GLN A H    1 c 
ATOM   2583 H HA   . GLN A 1 169 ? -17.315 -21.798 -7.922  1 46.19   ? 169 GLN A HA   1 c 
ATOM   2584 H HB2  . GLN A 1 169 ? -16.604 -22.665 -9.909  1 45.22   ? 169 GLN A HB2  1 c 
ATOM   2585 H HB3  . GLN A 1 169 ? -16.276 -24.062 -9.256  1 45.237  ? 169 GLN A HB3  1 c 
ATOM   2586 H HG2  . GLN A 1 169 ? -18.174 -24.453 -10.405 1 45.305  ? 169 GLN A HG2  1 c 
ATOM   2587 H HG3  . GLN A 1 169 ? -18.663 -24.366 -8.914  1 45.334  ? 169 GLN A HG3  1 c 
ATOM   2588 H HE21 . GLN A 1 169 ? -19.292 -20.884 -9.795  1 42.819  ? 169 GLN A HE21 1 c 
ATOM   2589 H HE22 . GLN A 1 169 ? -18.233 -21.363 -10.794 1 42.892  ? 169 GLN A HE22 1 c 
ATOM   2590 N N    . LEU A 1 170 ? -16.883 -24.475 -6.206  1 49.722  ? 170 LEU A N    1 ? 
ATOM   2591 C CA   . LEU A 1 170 ? -17.573 -25.396 -5.307  1 53.413  ? 170 LEU A CA   1 ? 
ATOM   2592 C C    . LEU A 1 170 ? -17.863 -24.726 -3.96   1 50.278  ? 170 LEU A C    1 ? 
ATOM   2593 O O    . LEU A 1 170 ? -18.853 -25.03  -3.315  1 47.109  ? 170 LEU A O    1 ? 
ATOM   2594 C CB   . LEU A 1 170 ? -16.756 -26.679 -5.183  1 55.546  ? 170 LEU A CB   1 ? 
ATOM   2595 C CG   . LEU A 1 170 ? -16.502 -27.429 -6.498  1 61.543  ? 170 LEU A CG   1 ? 
ATOM   2596 C CD1  . LEU A 1 170 ? -15.657 -28.668 -6.229  1 65.907  ? 170 LEU A CD1  1 ? 
ATOM   2597 C CD2  . LEU A 1 170 ? -17.803 -27.821 -7.205  1 59.077  ? 170 LEU A CD2  1 ? 
ATOM   2598 H H    . LEU A 1 170 ? -15.991 -24.591 -6.368  1 50.246  ? 170 LEU A H    1 c 
ATOM   2599 H HA   . LEU A 1 170 ? -18.447 -25.621 -5.717  1 52.505  ? 170 LEU A HA   1 c 
ATOM   2600 H HB2  . LEU A 1 170 ? -15.886 -26.453 -4.78   1 56.354  ? 170 LEU A HB2  1 c 
ATOM   2601 H HB3  . LEU A 1 170 ? -17.227 -27.285 -4.565  1 56.394  ? 170 LEU A HB3  1 c 
ATOM   2602 H HG   . LEU A 1 170 ? -15.989 -26.834 -7.103  1 60.575  ? 170 LEU A HG   1 c 
ATOM   2603 H HD11 . LEU A 1 170 ? -14.728 -28.407 -6.11   1 64.545  ? 170 LEU A HD11 1 c 
ATOM   2604 H HD12 . LEU A 1 170 ? -15.726 -29.281 -6.977  1 64.493  ? 170 LEU A HD12 1 c 
ATOM   2605 H HD13 . LEU A 1 170 ? -15.974 -29.108 -5.422  1 64.457  ? 170 LEU A HD13 1 c 
ATOM   2606 H HD21 . LEU A 1 170 ? -18.189 -27.037 -7.631  1 59.776  ? 170 LEU A HD21 1 c 
ATOM   2607 H HD22 . LEU A 1 170 ? -18.429 -28.174 -6.554  1 59.89   ? 170 LEU A HD22 1 c 
ATOM   2608 H HD23 . LEU A 1 170 ? -17.622 -28.497 -7.879  1 59.867  ? 170 LEU A HD23 1 c 
ATOM   2609 N N    . ASP A 1 171 ? -17.007 -23.79  -3.547  1 50.876  ? 171 ASP A N    1 ? 
ATOM   2610 C CA   . ASP A 1 171 ? -17.275 -22.971 -2.38   1 48.865  ? 171 ASP A CA   1 ? 
ATOM   2611 C C    . ASP A 1 171 ? -18.48  -22.059 -2.599  1 50.656  ? 171 ASP A C    1 ? 
ATOM   2612 O O    . ASP A 1 171 ? -19.275 -21.903 -1.671  1 53.413  ? 171 ASP A O    1 ? 
ATOM   2613 C CB   . ASP A 1 171 ? -16.03  -22.206 -1.986  1 50.925  ? 171 ASP A CB   1 ? 
ATOM   2614 C CG   . ASP A 1 171 ? -15.037 -23.051 -1.207  1 54.866  ? 171 ASP A CG   1 ? 
ATOM   2615 O OD1  . ASP A 1 171 ? -15.188 -24.301 -1.225  1 56.262  ? 171 ASP A OD1  1 ? 
ATOM   2616 O OD2  . ASP A 1 171 ? -14.171 -22.451 -0.555  1 57.571  ? 171 ASP A OD2  1 ? 
ATOM   2617 H H    . ASP A 1 171 ? -16.219 -23.672 -3.995  1 50.302  ? 171 ASP A H    1 c 
ATOM   2618 H HA   . ASP A 1 171 ? -17.496 -23.572 -1.633  1 50.025  ? 171 ASP A HA   1 c 
ATOM   2619 H HB2  . ASP A 1 171 ? -15.585 -21.855 -2.785  1 51.312  ? 171 ASP A HB2  1 c 
ATOM   2620 H HB3  . ASP A 1 171 ? -16.29  -21.446 -1.428  1 51.319  ? 171 ASP A HB3  1 c 
ATOM   2621 N N    . PHE A 1 172 ? -18.588 -21.473 -3.808  1 48.931  ? 172 PHE A N    1 ? 
ATOM   2622 C CA   . PHE A 1 172 ? -19.726 -20.655 -4.22   1 51.976  ? 172 PHE A CA   1 ? 
ATOM   2623 C C    . PHE A 1 172 ? -21.013 -21.473 -4.121  1 46.657  ? 172 PHE A C    1 ? 
ATOM   2624 O O    . PHE A 1 172 ? -21.998 -21.064 -3.491  1 45.369  ? 172 PHE A O    1 ? 
ATOM   2625 C CB   . PHE A 1 172 ? -19.522 -20.121 -5.648  1 53.178  ? 172 PHE A CB   1 ? 
ATOM   2626 C CG   . PHE A 1 172 ? -20.741 -19.413 -6.22   1 50.201  ? 172 PHE A CG   1 ? 
ATOM   2627 C CD1  . PHE A 1 172 ? -21.317 -18.338 -5.547  1 51.292  ? 172 PHE A CD1  1 ? 
ATOM   2628 C CD2  . PHE A 1 172 ? -21.354 -19.867 -7.383  1 53.301  ? 172 PHE A CD2  1 ? 
ATOM   2629 C CE1  . PHE A 1 172 ? -22.456 -17.715 -6.046  1 54.069  ? 172 PHE A CE1  1 ? 
ATOM   2630 C CE2  . PHE A 1 172 ? -22.499 -19.241 -7.879  1 58.286  ? 172 PHE A CE2  1 ? 
ATOM   2631 C CZ   . PHE A 1 172 ? -23.045 -18.166 -7.207  1 56.005  ? 172 PHE A CZ   1 ? 
ATOM   2632 H H    . PHE A 1 172 ? -17.902 -21.579 -4.404  1 50.033  ? 172 PHE A H    1 c 
ATOM   2633 H HA   . PHE A 1 172 ? -19.799 -19.883 -3.604  1 50.506  ? 172 PHE A HA   1 c 
ATOM   2634 H HB2  . PHE A 1 172 ? -18.765 -19.494 -5.64   1 52.214  ? 172 PHE A HB2  1 c 
ATOM   2635 H HB3  . PHE A 1 172 ? -19.285 -20.869 -6.233  1 52.222  ? 172 PHE A HB3  1 c 
ATOM   2636 H HD1  . PHE A 1 172 ? -20.926 -18.026 -4.746  1 51.758  ? 172 PHE A HD1  1 c 
ATOM   2637 H HD2  . PHE A 1 172 ? -20.988 -20.604 -7.845  1 53.67   ? 172 PHE A HD2  1 c 
ATOM   2638 H HE1  . PHE A 1 172 ? -22.829 -16.983 -5.584  1 53.864  ? 172 PHE A HE1  1 c 
ATOM   2639 H HE2  . PHE A 1 172 ? -22.895 -19.548 -8.679  1 56.465  ? 172 PHE A HE2  1 c 
ATOM   2640 H HZ   . PHE A 1 172 ? -23.813 -17.735 -7.546  1 55.978  ? 172 PHE A HZ   1 c 
ATOM   2641 N N    . ILE A 1 173 ? -20.984 -22.664 -4.715  1 47.95   ? 173 ILE A N    1 ? 
ATOM   2642 C CA   . ILE A 1 173 ? -22.178 -23.487 -4.783  1 46.435  ? 173 ILE A CA   1 ? 
ATOM   2643 C C    . ILE A 1 173 ? -22.588 -23.933 -3.389  1 49.786  ? 173 ILE A C    1 ? 
ATOM   2644 O O    . ILE A 1 173 ? -23.759 -23.841 -3.042  1 54.583  ? 173 ILE A O    1 ? 
ATOM   2645 C CB   . ILE A 1 173 ? -21.995 -24.681 -5.731  1 42.562  ? 173 ILE A CB   1 ? 
ATOM   2646 C CG1  . ILE A 1 173 ? -21.699 -24.219 -7.157  1 46.49   ? 173 ILE A CG1  1 ? 
ATOM   2647 C CG2  . ILE A 1 173 ? -23.224 -25.592 -5.691  1 45.37   ? 173 ILE A CG2  1 ? 
ATOM   2648 C CD1  . ILE A 1 173 ? -22.835 -23.451 -7.82   1 49.538  ? 173 ILE A CD1  1 ? 
ATOM   2649 H H    . ILE A 1 173 ? -20.206 -22.976 -5.079  1 47.291  ? 173 ILE A H    1 c 
ATOM   2650 H HA   . ILE A 1 173 ? -22.9   -22.934 -5.139  1 46.647  ? 173 ILE A HA   1 c 
ATOM   2651 H HB   . ILE A 1 173 ? -21.225 -25.197 -5.418  1 44.499  ? 173 ILE A HB   1 c 
ATOM   2652 H HG12 . ILE A 1 173 ? -20.905 -23.653 -7.152  1 46.279  ? 173 ILE A HG12 1 c 
ATOM   2653 H HG13 . ILE A 1 173 ? -21.499 -25.008 -7.698  1 46.206  ? 173 ILE A HG13 1 c 
ATOM   2654 H HG21 . ILE A 1 173 ? -23.283 -26.095 -6.521  1 44.577  ? 173 ILE A HG21 1 c 
ATOM   2655 H HG22 . ILE A 1 173 ? -24.027 -25.056 -5.583  1 44.587  ? 173 ILE A HG22 1 c 
ATOM   2656 H HG23 . ILE A 1 173 ? -23.147 -26.213 -4.947  1 44.619  ? 173 ILE A HG23 1 c 
ATOM   2657 H HD11 . ILE A 1 173 ? -23.691 -23.885 -7.652  1 48.594  ? 173 ILE A HD11 1 c 
ATOM   2658 H HD12 . ILE A 1 173 ? -22.678 -23.416 -8.782  1 48.571  ? 173 ILE A HD12 1 c 
ATOM   2659 H HD13 . ILE A 1 173 ? -22.859 -22.542 -7.465  1 48.592  ? 173 ILE A HD13 1 c 
ATOM   2660 N N    . ASP A 1 174 ? -21.625 -24.407 -2.602  1 53.005  ? 174 ASP A N    1 ? 
ATOM   2661 C CA   . ASP A 1 174 ? -21.915 -24.886 -1.257  1 55.376  ? 174 ASP A CA   1 ? 
ATOM   2662 C C    . ASP A 1 174 ? -22.532 -23.772 -0.414  1 49.62   ? 174 ASP A C    1 ? 
ATOM   2663 O O    . ASP A 1 174 ? -23.459 -24.018 0.347   1 46.344  ? 174 ASP A O    1 ? 
ATOM   2664 C CB   . ASP A 1 174 ? -20.678 -25.447 -0.559  1 57.722  ? 174 ASP A CB   1 ? 
ATOM   2665 C CG   . ASP A 1 174 ? -20.31  -26.882 -0.908  1 54.533  ? 174 ASP A CG   1 ? 
ATOM   2666 O OD1  . ASP A 1 174 ? -21.228 -27.709 -1.064  1 64.18   ? 174 ASP A OD1  1 ? 
ATOM   2667 O OD2  . ASP A 1 174 ? -19.111 -27.177 -0.938  1 59.646  ? 174 ASP A OD2  1 ? 
ATOM   2668 H H    . ASP A 1 174 ? -20.765 -24.449 -2.91   1 52.716  ? 174 ASP A H    1 c 
ATOM   2669 H HA   . ASP A 1 174 ? -22.576 -25.609 -1.331  1 54.272  ? 174 ASP A HA   1 c 
ATOM   2670 H HB2  . ASP A 1 174 ? -19.911 -24.875 -0.771  1 56.424  ? 174 ASP A HB2  1 c 
ATOM   2671 H HB3  . ASP A 1 174 ? -20.815 -25.409 0.411   1 56.392  ? 174 ASP A HB3  1 c 
ATOM   2672 N N    . PHE A 1 175 ? -21.995 -22.558 -0.528  1 45.513  ? 175 PHE A N    1 ? 
ATOM   2673 C CA   . PHE A 1 175 ? -22.587 -21.422 0.154   1 54.154  ? 175 PHE A CA   1 ? 
ATOM   2674 C C    . PHE A 1 175 ? -24.035 -21.203 -0.295  1 54.53   ? 175 PHE A C    1 ? 
ATOM   2675 O O    . PHE A 1 175 ? -24.919 -21.034 0.545   1 48.325  ? 175 PHE A O    1 ? 
ATOM   2676 C CB   . PHE A 1 175 ? -21.772 -20.159 -0.103  1 56.009  ? 175 PHE A CB   1 ? 
ATOM   2677 C CG   . PHE A 1 175 ? -22.502 -18.931 0.413   1 59.655  ? 175 PHE A CG   1 ? 
ATOM   2678 C CD1  . PHE A 1 175 ? -22.46  -18.594 1.765   1 59.308  ? 175 PHE A CD1  1 ? 
ATOM   2679 C CD2  . PHE A 1 175 ? -23.238 -18.132 -0.452  1 56.106  ? 175 PHE A CD2  1 ? 
ATOM   2680 C CE1  . PHE A 1 175 ? -23.137 -17.475 2.231   1 62.106  ? 175 PHE A CE1  1 ? 
ATOM   2681 C CE2  . PHE A 1 175 ? -23.907 -17.017 0.019   1 57.738  ? 175 PHE A CE2  1 ? 
ATOM   2682 C CZ   . PHE A 1 175 ? -23.868 -16.698 1.36    1 60.221  ? 175 PHE A CZ   1 ? 
ATOM   2683 H H    . PHE A 1 175 ? -21.238 -22.435 -1.026  1 48.491  ? 175 PHE A H    1 c 
ATOM   2684 H HA   . PHE A 1 175 ? -22.583 -21.606 1.131   1 52.698  ? 175 PHE A HA   1 c 
ATOM   2685 H HB2  . PHE A 1 175 ? -20.904 -20.239 0.351   1 56.282  ? 175 PHE A HB2  1 c 
ATOM   2686 H HB3  . PHE A 1 175 ? -21.619 -20.066 -1.069  1 56.25   ? 175 PHE A HB3  1 c 
ATOM   2687 H HD1  . PHE A 1 175 ? -21.968 -19.13  2.366   1 59.974  ? 175 PHE A HD1  1 c 
ATOM   2688 H HD2  . PHE A 1 175 ? -23.276 -18.35  -1.369  1 57.306  ? 175 PHE A HD2  1 c 
ATOM   2689 H HE1  . PHE A 1 175 ? -23.104 -17.254 3.148   1 60.931  ? 175 PHE A HE1  1 c 
ATOM   2690 H HE2  . PHE A 1 175 ? -24.406 -16.481 -0.578  1 57.966  ? 175 PHE A HE2  1 c 
ATOM   2691 H HZ   . PHE A 1 175 ? -24.32  -15.933 1.677   1 60.019  ? 175 PHE A HZ   1 c 
ATOM   2692 N N    . MET A 1 176 ? -24.272 -21.206 -1.618  1 54.826  ? 176 MET A N    1 ? 
ATOM   2693 C CA   . MET A 1 176 ? -25.612 -20.993 -2.147  1 51.173  ? 176 MET A CA   1 ? 
ATOM   2694 C C    . MET A 1 176 ? -26.556 -22.083 -1.648  1 53.016  ? 176 MET A C    1 ? 
ATOM   2695 O O    . MET A 1 176 ? -27.714 -21.784 -1.374  1 48.213  ? 176 MET A O    1 ? 
ATOM   2696 C CB   . MET A 1 176 ? -25.636 -20.939 -3.681  1 48.327  ? 176 MET A CB   1 ? 
ATOM   2697 C CG   . MET A 1 176 ? -24.921 -19.74  -4.3    1 52.125  ? 176 MET A CG   1 ? 
ATOM   2698 S SD   . MET A 1 176 ? -25.3   -18.115 -3.604  1 50.285  ? 176 MET A SD   1 ? 
ATOM   2699 C CE   . MET A 1 176 ? -27.075 -18.172 -3.896  1 47.862  ? 176 MET A CE   1 ? 
ATOM   2700 H H    . MET A 1 176 ? -23.581 -21.336 -2.202  1 53.818  ? 176 MET A H    1 c 
ATOM   2701 H HA   . MET A 1 176 ? -25.94  -20.132 -1.789  1 51.637  ? 176 MET A HA   1 c 
ATOM   2702 H HB2  . MET A 1 176 ? -25.223 -21.76  -4.024  1 49.813  ? 176 MET A HB2  1 c 
ATOM   2703 H HB3  . MET A 1 176 ? -26.571 -20.935 -3.977  1 49.818  ? 176 MET A HB3  1 c 
ATOM   2704 H HG2  . MET A 1 176 ? -23.962 -19.879 -4.226  1 50.8    ? 176 MET A HG2  1 c 
ATOM   2705 H HG3  . MET A 1 176 ? -25.134 -19.714 -5.254  1 50.831  ? 176 MET A HG3  1 c 
ATOM   2706 H HE1  . MET A 1 176 ? -27.446 -17.274 -3.817  1 48.455  ? 176 MET A HE1  1 c 
ATOM   2707 H HE2  . MET A 1 176 ? -27.245 -18.516 -4.792  1 48.455  ? 176 MET A HE2  1 c 
ATOM   2708 H HE3  . MET A 1 176 ? -27.493 -18.757 -3.238  1 48.454  ? 176 MET A HE3  1 c 
ATOM   2709 N N    . ASN A 1 177 ? -26.065 -23.323 -1.503  1 50.366  ? 177 ASN A N    1 ? 
ATOM   2710 C CA   . ASN A 1 177 ? -26.904 -24.408 -1.007  1 50.843  ? 177 ASN A CA   1 ? 
ATOM   2711 C C    . ASN A 1 177 ? -27.27  -24.208 0.459   1 48.201  ? 177 ASN A C    1 ? 
ATOM   2712 O O    . ASN A 1 177 ? -28.363 -24.565 0.878   1 45.935  ? 177 ASN A O    1 ? 
ATOM   2713 C CB   . ASN A 1 177 ? -26.231 -25.769 -1.133  1 47.822  ? 177 ASN A CB   1 ? 
ATOM   2714 C CG   . ASN A 1 177 ? -26.149 -26.236 -2.563  1 49.273  ? 177 ASN A CG   1 ? 
ATOM   2715 O OD1  . ASN A 1 177 ? -26.97  -25.861 -3.407  1 51.347  ? 177 ASN A OD1  1 ? 
ATOM   2716 N ND2  . ASN A 1 177 ? -25.2   -27.11  -2.847  1 55.005  ? 177 ASN A ND2  1 ? 
ATOM   2717 H H    . ASN A 1 177 ? -25.198 -23.504 -1.73   1 51.099  ? 177 ASN A H    1 c 
ATOM   2718 H HA   . ASN A 1 177 ? -27.734 -24.429 -1.534  1 49.706  ? 177 ASN A HA   1 c 
ATOM   2719 H HB2  . ASN A 1 177 ? -25.328 -25.716 -0.761  1 48.825  ? 177 ASN A HB2  1 c 
ATOM   2720 H HB3  . ASN A 1 177 ? -26.734 -26.428 -0.612  1 48.821  ? 177 ASN A HB3  1 c 
ATOM   2721 H HD21 . ASN A 1 177 ? -24.913 -27.192 -3.682  1 53.076  ? 177 ASN A HD21 1 c 
ATOM   2722 H HD22 . ASN A 1 177 ? -24.852 -27.615 -2.206  1 53.113  ? 177 ASN A HD22 1 c 
ATOM   2723 N N    . GLN A 1 178 ? -26.335 -23.681 1.245   1 48.868  ? 178 GLN A N    1 ? 
ATOM   2724 C CA   . GLN A 1 178 ? -26.594 -23.463 2.66    1 57.156  ? 178 GLN A CA   1 ? 
ATOM   2725 C C    . GLN A 1 178 ? -27.712 -22.431 2.821   1 57.212  ? 178 GLN A C    1 ? 
ATOM   2726 O O    . GLN A 1 178 ? -28.716 -22.675 3.493   1 55.301  ? 178 GLN A O    1 ? 
ATOM   2727 C CB   . GLN A 1 178 ? -25.325 -23.016 3.391   1 54.446  ? 178 GLN A CB   1 ? 
ATOM   2728 C CG   . GLN A 1 178 ? -24.336 -24.145 3.645   1 62.219  ? 178 GLN A CG   1 ? 
ATOM   2729 C CD   . GLN A 1 178 ? -24.77  -25.092 4.743   1 68.645  ? 178 GLN A CD   1 ? 
ATOM   2730 O OE1  . GLN A 1 178 ? -25.74  -24.848 5.473   1 62.467  ? 178 GLN A OE1  1 ? 
ATOM   2731 N NE2  . GLN A 1 178 ? -24.033 -26.187 4.877   1 67.593  ? 178 GLN A NE2  1 ? 
ATOM   2732 H H    . GLN A 1 178 ? -25.514 -23.467 0.906   1 50.529  ? 178 GLN A H    1 c 
ATOM   2733 H HA   . GLN A 1 178 ? -26.9   -24.318 3.054   1 54.919  ? 178 GLN A HA   1 c 
ATOM   2734 H HB2  . GLN A 1 178 ? -24.883 -22.321 2.861   1 56.679  ? 178 GLN A HB2  1 c 
ATOM   2735 H HB3  . GLN A 1 178 ? -25.579 -22.617 4.248   1 56.824  ? 178 GLN A HB3  1 c 
ATOM   2736 H HG2  . GLN A 1 178 ? -24.217 -24.66  2.819   1 61.686  ? 178 GLN A HG2  1 c 
ATOM   2737 H HG3  . GLN A 1 178 ? -23.466 -23.763 3.885   1 61.73   ? 178 GLN A HG3  1 c 
ATOM   2738 H HE21 . GLN A 1 178 ? -24.106 -26.68  5.611   1 67.85   ? 178 GLN A HE21 1 c 
ATOM   2739 H HE22 . GLN A 1 178 ? -23.468 -26.429 4.236   1 67.811  ? 178 GLN A HE22 1 c 
ATOM   2740 N N    . ILE A 1 179 ? -27.548 -21.277 2.176   1 49.901  ? 179 ILE A N    1 ? 
ATOM   2741 C CA   . ILE A 1 179 ? -28.573 -20.258 2.297   1 52.274  ? 179 ILE A CA   1 ? 
ATOM   2742 C C    . ILE A 1 179 ? -29.865 -20.749 1.647   1 47.315  ? 179 ILE A C    1 ? 
ATOM   2743 O O    . ILE A 1 179 ? -30.93  -20.406 2.139   1 54.567  ? 179 ILE A O    1 ? 
ATOM   2744 C CB   . ILE A 1 179 ? -28.099 -18.877 1.809   1 50.546  ? 179 ILE A CB   1 ? 
ATOM   2745 C CG1  . ILE A 1 179 ? -27.79  -18.802 0.311   1 51.453  ? 179 ILE A CG1  1 ? 
ATOM   2746 C CG2  . ILE A 1 179 ? -26.908 -18.419 2.647   1 51.369  ? 179 ILE A CG2  1 ? 
ATOM   2747 C CD1  . ILE A 1 179 ? -27.737 -17.379 -0.217  1 50.5    ? 179 ILE A CD1  1 ? 
ATOM   2748 H H    . ILE A 1 179 ? -26.806 -21.12  1.667   1 52.085  ? 179 ILE A H    1 c 
ATOM   2749 H HA   . ILE A 1 179 ? -28.76  -20.158 3.252   1 50.621  ? 179 ILE A HA   1 c 
ATOM   2750 H HB   . ILE A 1 179 ? -28.829 -18.25  1.98    1 51.208  ? 179 ILE A HB   1 c 
ATOM   2751 H HG12 . ILE A 1 179 ? -26.927 -19.233 0.146   1 51.022  ? 179 ILE A HG12 1 c 
ATOM   2752 H HG13 . ILE A 1 179 ? -28.474 -19.296 -0.185  1 50.983  ? 179 ILE A HG13 1 c 
ATOM   2753 H HG21 . ILE A 1 179 ? -26.669 -17.51  2.403   1 51.216  ? 179 ILE A HG21 1 c 
ATOM   2754 H HG22 . ILE A 1 179 ? -26.149 -19.003 2.485   1 51.147  ? 179 ILE A HG22 1 c 
ATOM   2755 H HG23 . ILE A 1 179 ? -27.141 -18.447 3.59    1 51.144  ? 179 ILE A HG23 1 c 
ATOM   2756 H HD11 . ILE A 1 179 ? -28.549 -16.902 0.039   1 50.737  ? 179 ILE A HD11 1 c 
ATOM   2757 H HD12 . ILE A 1 179 ? -27.666 -17.398 -1.19   1 50.723  ? 179 ILE A HD12 1 c 
ATOM   2758 H HD13 . ILE A 1 179 ? -26.96  -16.919 0.154   1 50.763  ? 179 ILE A HD13 1 c 
ATOM   2759 N N    . ALA A 1 180 ? -29.799 -21.615 0.627   1 49.684  ? 180 ALA A N    1 ? 
ATOM   2760 C CA   . ALA A 1 180 ? -31.027 -22.213 0.099   1 53.615  ? 180 ALA A CA   1 ? 
ATOM   2761 C C    . ALA A 1 180 ? -31.765 -22.969 1.196   1 59.349  ? 180 ALA A C    1 ? 
ATOM   2762 O O    . ALA A 1 180 ? -32.992 -22.88  1.316   1 62.858  ? 180 ALA A O    1 ? 
ATOM   2763 C CB   . ALA A 1 180 ? -30.751 -23.146 -1.061  1 48.636  ? 180 ALA A CB   1 ? 
ATOM   2764 H H    . ALA A 1 180 ? -28.997 -21.824 0.242   1 49.973  ? 180 ALA A H    1 c 
ATOM   2765 H HA   . ALA A 1 180 ? -31.618 -21.474 -0.216  1 52.882  ? 180 ALA A HA   1 c 
ATOM   2766 H HB1  . ALA A 1 180 ? -30.179 -22.703 -1.709  1 50.062  ? 180 ALA A HB1  1 c 
ATOM   2767 H HB2  . ALA A 1 180 ? -30.31  -23.95  -0.741  1 50.082  ? 180 ALA A HB2  1 c 
ATOM   2768 H HB3  . ALA A 1 180 ? -31.589 -23.39  -1.489  1 50.065  ? 180 ALA A HB3  1 c 
ATOM   2769 N N    . SER A 1 181 ? -30.976 -23.732 1.959   1 57.535  ? 181 SER A N    1 ? 
ATOM   2770 C CA   . SER A 1 181 ? -31.466 -24.585 3.025   1 54.013  ? 181 SER A CA   1 ? 
ATOM   2771 C C    . SER A 1 181 ? -32.246 -23.749 4.043   1 48.421  ? 181 SER A C    1 ? 
ATOM   2772 O O    . SER A 1 181 ? -33.362 -24.096 4.406   1 51.514  ? 181 SER A O    1 ? 
ATOM   2773 C CB   . SER A 1 181 ? -30.289 -25.316 3.66    1 55.357  ? 181 SER A CB   1 ? 
ATOM   2774 O OG   . SER A 1 181 ? -30.7   -26.28  4.616   1 57.054  ? 181 SER A OG   1 ? 
ATOM   2775 H H    . SER A 1 181 ? -30.078 -23.735 1.791   1 57.026  ? 181 SER A H    1 c 
ATOM   2776 H HA   . SER A 1 181 ? -32.081 -25.255 2.631   1 53.845  ? 181 SER A HA   1 c 
ATOM   2777 H HB2  . SER A 1 181 ? -29.772 -25.759 2.96    1 55.461  ? 181 SER A HB2  1 c 
ATOM   2778 H HB3  . SER A 1 181 ? -29.71  -24.671 4.097   1 55.451  ? 181 SER A HB3  1 c 
ATOM   2779 N N    . THR A 1 182 ? -31.657 -22.643 4.497   1 45.187  ? 182 THR A N    1 ? 
ATOM   2780 C CA   . THR A 1 182 ? -32.329 -21.75  5.425   1 51.151  ? 182 THR A CA   1 ? 
ATOM   2781 C C    . THR A 1 182 ? -33.725 -21.397 4.898   1 58.886  ? 182 THR A C    1 ? 
ATOM   2782 O O    . THR A 1 182 ? -34.71  -21.544 5.613   1 58.516  ? 182 THR A O    1 ? 
ATOM   2783 C CB   . THR A 1 182 ? -31.485 -20.497 5.637   1 56.37   ? 182 THR A CB   1 ? 
ATOM   2784 O OG1  . THR A 1 182 ? -30.16  -20.87  6.018   1 51.516  ? 182 THR A OG1  1 ? 
ATOM   2785 C CG2  . THR A 1 182 ? -32.08  -19.587 6.696   1 58.137  ? 182 THR A CG2  1 ? 
ATOM   2786 H H    . THR A 1 182 ? -30.806 -22.442 4.231   1 47.4    ? 182 THR A H    1 c 
ATOM   2787 H HA   . THR A 1 182 ? -32.424 -22.214 6.285   1 52.179  ? 182 THR A HA   1 c 
ATOM   2788 H HB   . THR A 1 182 ? -31.443 -19.995 4.789   1 54.729  ? 182 THR A HB   1 c 
ATOM   2789 H HG21 . THR A 1 182 ? -31.381 -19.024 7.07    1 57.55   ? 182 THR A HG21 1 c 
ATOM   2790 H HG22 . THR A 1 182 ? -32.474 -20.125 7.404   1 57.521  ? 182 THR A HG22 1 c 
ATOM   2791 H HG23 . THR A 1 182 ? -32.765 -19.027 6.295   1 57.586  ? 182 THR A HG23 1 c 
ATOM   2792 N N    . VAL A 1 183 ? -33.818 -20.933 3.64    1 64.702  ? 183 VAL A N    1 ? 
ATOM   2793 C CA   . VAL A 1 183 ? -35.057 -20.354 3.129   1 54.193  ? 183 VAL A CA   1 ? 
ATOM   2794 C C    . VAL A 1 183 ? -36.068 -21.466 2.863   1 53.92   ? 183 VAL A C    1 ? 
ATOM   2795 O O    . VAL A 1 183 ? -37.265 -21.25  3.026   1 56.028  ? 183 VAL A O    1 ? 
ATOM   2796 C CB   . VAL A 1 183 ? -34.898 -19.425 1.905   1 51.609  ? 183 VAL A CB   1 ? 
ATOM   2797 C CG1  . VAL A 1 183 ? -33.787 -18.402 2.127   1 53.355  ? 183 VAL A CG1  1 ? 
ATOM   2798 C CG2  . VAL A 1 183 ? -34.681 -20.164 0.587   1 49.575  ? 183 VAL A CG2  1 ? 
ATOM   2799 H H    . VAL A 1 183 ? -33.092 -20.979 3.087   1 60.569  ? 183 VAL A H    1 c 
ATOM   2800 H HA   . VAL A 1 183 ? -35.427 -19.803 3.846   1 55.565  ? 183 VAL A HA   1 c 
ATOM   2801 H HB   . VAL A 1 183 ? -35.742 -18.922 1.819   1 52.045  ? 183 VAL A HB   1 c 
ATOM   2802 H HG11 . VAL A 1 183 ? -32.944 -18.762 1.806   1 52.828  ? 183 VAL A HG11 1 c 
ATOM   2803 H HG12 . VAL A 1 183 ? -33.713 -18.202 3.075   1 52.846  ? 183 VAL A HG12 1 c 
ATOM   2804 H HG13 . VAL A 1 183 ? -33.995 -17.587 1.641   1 52.836  ? 183 VAL A HG13 1 c 
ATOM   2805 H HG21 . VAL A 1 183 ? -34.549 -19.517 -0.126  1 50.172  ? 183 VAL A HG21 1 c 
ATOM   2806 H HG22 . VAL A 1 183 ? -35.457 -20.712 0.381   1 50.197  ? 183 VAL A HG22 1 c 
ATOM   2807 H HG23 . VAL A 1 183 ? -33.895 -20.727 0.656   1 50.241  ? 183 VAL A HG23 1 c 
ATOM   2808 N N    . LYS A 1 184 ? -35.619 -22.669 2.501   1 52.527  ? 184 LYS A N    1 ? 
ATOM   2809 C CA   . LYS A 1 184 ? -36.572 -23.768 2.366   1 55.744  ? 184 LYS A CA   1 ? 
ATOM   2810 C C    . LYS A 1 184 ? -37.148 -24.139 3.733   1 59.552  ? 184 LYS A C    1 ? 
ATOM   2811 O O    . LYS A 1 184 ? -38.283 -24.611 3.841   1 52.48   ? 184 LYS A O    1 ? 
ATOM   2812 C CB   . LYS A 1 184 ? -35.929 -24.984 1.697   1 57.928  ? 184 LYS A CB   1 ? 
ATOM   2813 C CG   . LYS A 1 184 ? -35.45  -24.734 0.275   1 59.521  ? 184 LYS A CG   1 ? 
ATOM   2814 C CD   . LYS A 1 184 ? -34.335 -25.667 -0.165  1 64.084  ? 184 LYS A CD   1 ? 
ATOM   2815 C CE   . LYS A 1 184 ? -34.866 -27.035 -0.43   1 66.292  ? 184 LYS A CE   1 ? 
ATOM   2816 N NZ   . LYS A 1 184 ? -33.811 -27.95  -0.874  1 70.076  ? 184 LYS A NZ   1 ? 
ATOM   2817 H H    . LYS A 1 184 ? -34.734 -22.811 2.323   1 53.735  ? 184 LYS A H    1 c 
ATOM   2818 H HA   . LYS A 1 184 ? -37.316 -23.465 1.784   1 56.157  ? 184 LYS A HA   1 c 
ATOM   2819 H HB2  . LYS A 1 184 ? -35.165 -25.275 2.239   1 57.854  ? 184 LYS A HB2  1 c 
ATOM   2820 H HB3  . LYS A 1 184 ? -36.58  -25.718 1.681   1 57.798  ? 184 LYS A HB3  1 c 
ATOM   2821 H HG2  . LYS A 1 184 ? -36.214 -24.841 -0.333  1 60.21   ? 184 LYS A HG2  1 c 
ATOM   2822 H HG3  . LYS A 1 184 ? -35.14  -23.807 0.202   1 60.075  ? 184 LYS A HG3  1 c 
ATOM   2823 H HD2  . LYS A 1 184 ? -33.921 -25.316 -0.983  1 63.519  ? 184 LYS A HD2  1 c 
ATOM   2824 H HD3  . LYS A 1 184 ? -33.65  -25.714 0.537   1 63.514  ? 184 LYS A HD3  1 c 
ATOM   2825 H HE2  . LYS A 1 184 ? -35.269 -27.393 0.381   1 66.599  ? 184 LYS A HE2  1 c 
ATOM   2826 H HE3  . LYS A 1 184 ? -35.556 -26.989 -1.115  1 66.595  ? 184 LYS A HE3  1 c 
ATOM   2827 H HZ1  . LYS A 1 184 ? -32.997 -27.674 -0.587  1 68.8    ? 184 LYS A HZ1  1 c 
ATOM   2828 H HZ2  . LYS A 1 184 ? -33.81  -27.991 -1.779  1 68.791  ? 184 LYS A HZ2  1 c 
ATOM   2829 H HZ3  . LYS A 1 184 ? -33.972 -28.778 -0.544  1 68.854  ? 184 LYS A HZ3  1 c 
ATOM   2830 N N    . GLU A 1 185 ? -36.367 -23.881 4.789   1 60.517  ? 185 GLU A N    1 ? 
ATOM   2831 C CA   . GLU A 1 185 ? -36.844 -24.128 6.136   1 69.453  ? 185 GLU A CA   1 ? 
ATOM   2832 C C    . GLU A 1 185 ? -38.119 -23.311 6.367   1 70.323  ? 185 GLU A C    1 ? 
ATOM   2833 O O    . GLU A 1 185 ? -39.009 -23.787 7.064   1 64.609  ? 185 GLU A O    1 ? 
ATOM   2834 C CB   . GLU A 1 185 ? -35.727 -23.958 7.174   1 74.619  ? 185 GLU A CB   1 ? 
ATOM   2835 C CG   . GLU A 1 185 ? -35.069 -25.264 7.622   1 82.428  ? 185 GLU A CG   1 ? 
ATOM   2836 C CD   . GLU A 1 185 ? -33.596 -25.153 8.001   1 87.655  ? 185 GLU A CD   1 ? 
ATOM   2837 O OE1  . GLU A 1 185 ? -32.862 -26.128 7.724   1 91.964  ? 185 GLU A OE1  1 ? 
ATOM   2838 O OE2  . GLU A 1 185 ? -33.163 -24.104 8.528   1 81.305  ? 185 GLU A OE2  1 ? 
ATOM   2839 H H    . GLU A 1 185 ? -35.509 -23.594 4.668   1 62.178  ? 185 GLU A H    1 c 
ATOM   2840 H HA   . GLU A 1 185 ? -37.112 -25.081 6.178   1 68.673  ? 185 GLU A HA   1 c 
ATOM   2841 H HB2  . GLU A 1 185 ? -35.032 -23.383 6.808   1 74.869  ? 185 GLU A HB2  1 c 
ATOM   2842 H HB3  . GLU A 1 185 ? -36.096 -23.511 7.964   1 75.033  ? 185 GLU A HB3  1 c 
ATOM   2843 H HG2  . GLU A 1 185 ? -35.56  -25.615 8.396   1 81.708  ? 185 GLU A HG2  1 c 
ATOM   2844 H HG3  . GLU A 1 185 ? -35.15  -25.925 6.902   1 81.619  ? 185 GLU A HG3  1 c 
ATOM   2845 N N    . SER A 1 186 ? -38.227 -22.127 5.733   1 66.802  ? 186 SER A N    1 ? 
ATOM   2846 C CA   . SER A 1 186 ? -39.411 -21.285 5.841   1 62.145  ? 186 SER A CA   1 ? 
ATOM   2847 C C    . SER A 1 186 ? -40.359 -21.44  4.652   1 58.584  ? 186 SER A C    1 ? 
ATOM   2848 O O    . SER A 1 186 ? -41.235 -20.603 4.507   1 59.512  ? 186 SER A O    1 ? 
ATOM   2849 C CB   . SER A 1 186 ? -39.034 -19.838 6.019   1 57.471  ? 186 SER A CB   1 ? 
ATOM   2850 O OG   . SER A 1 186 ? -38.134 -19.677 7.106   1 60.958  ? 186 SER A OG   1 ? 
ATOM   2851 H H    . SER A 1 186 ? -37.518 -21.81  5.253   1 66.383  ? 186 SER A H    1 c 
ATOM   2852 H HA   . SER A 1 186 ? -39.908 -21.561 6.652   1 61.5    ? 186 SER A HA   1 c 
ATOM   2853 H HB2  . SER A 1 186 ? -38.616 -19.509 5.2     1 59.324  ? 186 SER A HB2  1 c 
ATOM   2854 H HB3  . SER A 1 186 ? -39.837 -19.309 6.186   1 59.325  ? 186 SER A HB3  1 c 
ATOM   2855 N N    . LYS A 1 187 ? -40.19  -22.478 3.813   1 60.011  ? 187 LYS A N    1 ? 
ATOM   2856 C CA   . LYS A 1 187 ? -41.135 -22.854 2.757   1 63.086  ? 187 LYS A CA   1 ? 
ATOM   2857 C C    . LYS A 1 187 ? -41.081 -21.911 1.539   1 61.538  ? 187 LYS A C    1 ? 
ATOM   2858 O O    . LYS A 1 187 ? -41.993 -21.928 0.702   1 63.086  ? 187 LYS A O    1 ? 
ATOM   2859 C CB   . LYS A 1 187 ? -42.592 -23.027 3.237   1 70.499  ? 187 LYS A CB   1 ? 
ATOM   2860 C CG   . LYS A 1 187 ? -42.971 -24.317 3.994   1 73.557  ? 187 LYS A CG   1 ? 
ATOM   2861 C CD   . LYS A 1 187 ? -43.075 -24.227 5.517   1 73.493  ? 187 LYS A CD   1 ? 
ATOM   2862 H H    . LYS A 1 187 ? -39.44  -22.987 3.901   1 60.451  ? 187 LYS A H    1 c 
ATOM   2863 H HA   . LYS A 1 187 ? -40.855 -23.747 2.434   1 63.547  ? 187 LYS A HA   1 c 
ATOM   2864 H HB2  . LYS A 1 187 ? -42.828 -22.265 3.803   1 69.298  ? 187 LYS A HB2  1 c 
ATOM   2865 H HB3  . LYS A 1 187 ? -43.175 -22.981 2.45    1 69.308  ? 187 LYS A HB3  1 c 
ATOM   2866 H HG2  . LYS A 1 187 ? -43.835 -24.628 3.644   1 72.825  ? 187 LYS A HG2  1 c 
ATOM   2867 H HG3  . LYS A 1 187 ? -42.308 -25.006 3.77    1 72.771  ? 187 LYS A HG3  1 c 
ATOM   2868 N N    . TYR A 1 188 ? -40.017 -21.108 1.404   1 51.543  ? 188 TYR A N    1 ? 
ATOM   2869 C CA   . TYR A 1 188 ? -39.795 -20.33  0.195   1 52.799  ? 188 TYR A CA   1 ? 
ATOM   2870 C C    . TYR A 1 188 ? -39.063 -21.191 -0.834  1 54.904  ? 188 TYR A C    1 ? 
ATOM   2871 O O    . TYR A 1 188 ? -38.326 -22.111 -0.489  1 61.828  ? 188 TYR A O    1 ? 
ATOM   2872 C CB   . TYR A 1 188 ? -38.948 -19.078 0.422   1 56.101  ? 188 TYR A CB   1 ? 
ATOM   2873 C CG   . TYR A 1 188 ? -39.546 -17.916 1.209   1 59.73   ? 188 TYR A CG   1 ? 
ATOM   2874 C CD1  . TYR A 1 188 ? -40.177 -18.082 2.444   1 63.242  ? 188 TYR A CD1  1 ? 
ATOM   2875 C CD2  . TYR A 1 188 ? -39.449 -16.62  0.71    1 58.061  ? 188 TYR A CD2  1 ? 
ATOM   2876 C CE1  . TYR A 1 188 ? -40.677 -16.994 3.152   1 63.702  ? 188 TYR A CE1  1 ? 
ATOM   2877 C CE2  . TYR A 1 188 ? -39.938 -15.527 1.408   1 61.19   ? 188 TYR A CE2  1 ? 
ATOM   2878 C CZ   . TYR A 1 188 ? -40.561 -15.712 2.63    1 63.493  ? 188 TYR A CZ   1 ? 
ATOM   2879 O OH   . TYR A 1 188 ? -41.031 -14.598 3.267   1 58.476  ? 188 TYR A OH   1 ? 
ATOM   2880 H H    . TYR A 1 188 ? -39.4   -21.05  2.075   1 54.239  ? 188 TYR A H    1 c 
ATOM   2881 H HA   . TYR A 1 188 ? -40.674 -20.053 -0.177  1 53.621  ? 188 TYR A HA   1 c 
ATOM   2882 H HB2  . TYR A 1 188 ? -38.122 -19.357 0.876   1 56.131  ? 188 TYR A HB2  1 c 
ATOM   2883 H HB3  . TYR A 1 188 ? -38.675 -18.739 -0.46   1 56.149  ? 188 TYR A HB3  1 c 
ATOM   2884 H HD1  . TYR A 1 188 ? -40.248 -18.944 2.814   1 62.288  ? 188 TYR A HD1  1 c 
ATOM   2885 H HD2  . TYR A 1 188 ? -39.019 -16.479 -0.115  1 58.981  ? 188 TYR A HD2  1 c 
ATOM   2886 H HE1  . TYR A 1 188 ? -41.098 -17.126 3.984   1 63.429  ? 188 TYR A HE1  1 c 
ATOM   2887 H HE2  . TYR A 1 188 ? -39.861 -14.661 1.045   1 60.95   ? 188 TYR A HE2  1 c 
ATOM   2888 N N    . GLU A 1 189 ? -39.284 -20.886 -2.111  1 52.938  ? 189 GLU A N    1 ? 
ATOM   2889 C CA   . GLU A 1 189 ? -38.449 -21.384 -3.188  1 53.718  ? 189 GLU A CA   1 ? 
ATOM   2890 C C    . GLU A 1 189 ? -37.284 -20.411 -3.377  1 54.099  ? 189 GLU A C    1 ? 
ATOM   2891 O O    . GLU A 1 189 ? -37.505 -19.204 -3.544  1 51.346  ? 189 GLU A O    1 ? 
ATOM   2892 C CB   . GLU A 1 189 ? -39.252 -21.519 -4.479  1 52.11   ? 189 GLU A CB   1 ? 
ATOM   2893 C CG   . GLU A 1 189 ? -38.401 -21.85  -5.703  1 56.461  ? 189 GLU A CG   1 ? 
ATOM   2894 C CD   . GLU A 1 189 ? -39.129 -21.917 -7.034  1 49.741  ? 189 GLU A CD   1 ? 
ATOM   2895 O OE1  . GLU A 1 189 ? -40.142 -22.622 -7.093  1 54.411  ? 189 GLU A OE1  1 ? 
ATOM   2896 O OE2  . GLU A 1 189 ? -38.656 -21.3   -8.016  1 53.886  ? 189 GLU A OE2  1 ? 
ATOM   2897 H H    . GLU A 1 189 ? -39.987 -20.341 -2.322  1 53.561  ? 189 GLU A H    1 c 
ATOM   2898 H HA   . GLU A 1 189 ? -38.11  -22.277 -2.941  1 53.371  ? 189 GLU A HA   1 c 
ATOM   2899 H HB2  . GLU A 1 189 ? -39.925 -22.222 -4.36   1 53.431  ? 189 GLU A HB2  1 c 
ATOM   2900 H HB3  . GLU A 1 189 ? -39.725 -20.679 -4.645  1 53.401  ? 189 GLU A HB3  1 c 
ATOM   2901 H HG2  . GLU A 1 189 ? -37.691 -21.181 -5.786  1 53.845  ? 189 GLU A HG2  1 c 
ATOM   2902 H HG3  . GLU A 1 189 ? -37.963 -22.714 -5.552  1 53.846  ? 189 GLU A HG3  1 c 
ATOM   2903 N N    . PRO A 1 190 ? -36.022 -20.905 -3.378  1 50.416  ? 190 PRO A N    1 ? 
ATOM   2904 C CA   . PRO A 1 190 ? -34.863 -20.054 -3.589  1 46.01   ? 190 PRO A CA   1 ? 
ATOM   2905 C C    . PRO A 1 190 ? -34.613 -19.82  -5.071  1 40.102  ? 190 PRO A C    1 ? 
ATOM   2906 O O    . PRO A 1 190 ? -34.936 -20.671 -5.881  1 40.691  ? 190 PRO A O    1 ? 
ATOM   2907 C CB   . PRO A 1 190 ? -33.741 -20.863 -2.952  1 49.454  ? 190 PRO A CB   1 ? 
ATOM   2908 C CG   . PRO A 1 190 ? -34.114 -22.303 -3.284  1 46.268  ? 190 PRO A CG   1 ? 
ATOM   2909 C CD   . PRO A 1 190 ? -35.636 -22.326 -3.24   1 55.207  ? 190 PRO A CD   1 ? 
ATOM   2910 H HA   . PRO A 1 190 ? -34.978 -19.2   -3.122  1 46.284  ? 190 PRO A HA   1 c 
ATOM   2911 H HB2  . PRO A 1 190 ? -32.875 -20.627 -3.336  1 47.888  ? 190 PRO A HB2  1 c 
ATOM   2912 H HB3  . PRO A 1 190 ? -33.711 -20.722 -1.987  1 47.945  ? 190 PRO A HB3  1 c 
ATOM   2913 H HG2  . PRO A 1 190 ? -33.791 -22.552 -4.172  1 48.899  ? 190 PRO A HG2  1 c 
ATOM   2914 H HG3  . PRO A 1 190 ? -33.741 -22.921 -2.625  1 48.883  ? 190 PRO A HG3  1 c 
ATOM   2915 H HD2  . PRO A 1 190 ? -36.003 -22.855 -3.974  1 51.968  ? 190 PRO A HD2  1 c 
ATOM   2916 H HD3  . PRO A 1 190 ? -35.954 -22.688 -2.39   1 51.972  ? 190 PRO A HD3  1 c 
ATOM   2917 N N    . GLN A 1 191 ? -33.979 -18.697 -5.4    1 38.08   ? 191 GLN A N    1 ? 
ATOM   2918 C CA   . GLN A 1 191 ? -33.73  -18.295 -6.773  1 38.956  ? 191 GLN A CA   1 ? 
ATOM   2919 C C    . GLN A 1 191 ? -32.382 -17.586 -6.81   1 37.553  ? 191 GLN A C    1 ? 
ATOM   2920 O O    . GLN A 1 191 ? -31.988 -17.002 -5.814  1 39.392  ? 191 GLN A O    1 ? 
ATOM   2921 C CB   . GLN A 1 191 ? -34.786 -17.31  -7.302  1 41.4    ? 191 GLN A CB   1 ? 
ATOM   2922 C CG   . GLN A 1 191 ? -36.238 -17.793 -7.243  1 45.382  ? 191 GLN A CG   1 ? 
ATOM   2923 C CD   . GLN A 1 191 ? -37.2   -16.852 -7.953  1 48.508  ? 191 GLN A CD   1 ? 
ATOM   2924 O OE1  . GLN A 1 191 ? -37.499 -15.76  -7.466  1 52.381  ? 191 GLN A OE1  1 ? 
ATOM   2925 N NE2  . GLN A 1 191 ? -37.672 -17.227 -9.135  1 47.661  ? 191 GLN A NE2  1 ? 
ATOM   2926 H H    . GLN A 1 191 ? -33.688 -18.148 -4.729  1 38.843  ? 191 GLN A H    1 c 
ATOM   2927 H HA   . GLN A 1 191 ? -33.691 -19.097 -7.341  1 38.994  ? 191 GLN A HA   1 c 
ATOM   2928 H HB2  . GLN A 1 191 ? -34.715 -16.478 -6.791  1 41.709  ? 191 GLN A HB2  1 c 
ATOM   2929 H HB3  . GLN A 1 191 ? -34.566 -17.099 -8.234  1 41.696  ? 191 GLN A HB3  1 c 
ATOM   2930 H HG2  . GLN A 1 191 ? -36.299 -18.682 -7.639  1 45.168  ? 191 GLN A HG2  1 c 
ATOM   2931 H HG3  . GLN A 1 191 ? -36.513 -17.868 -6.304  1 45.141  ? 191 GLN A HG3  1 c 
ATOM   2932 H HE21 . GLN A 1 191 ? -38.273 -16.724 -9.55   1 47.97   ? 191 GLN A HE21 1 c 
ATOM   2933 H HE22 . GLN A 1 191 ? -37.387 -17.976 -9.517  1 47.891  ? 191 GLN A HE22 1 c 
ATOM   2934 N N    . MET A 1 192 ? -31.725 -17.567 -7.974  1 38.654  ? 192 MET A N    1 ? 
ATOM   2935 C CA   . MET A 1 192 ? -30.449 -16.881 -8.115  1 40.471  ? 192 MET A CA   1 ? 
ATOM   2936 C C    . MET A 1 192 ? -30.254 -16.498 -9.578  1 39.654  ? 192 MET A C    1 ? 
ATOM   2937 O O    . MET A 1 192 ? -30.87  -17.069 -10.473 1 43.22   ? 192 MET A O    1 ? 
ATOM   2938 C CB   . MET A 1 192 ? -29.282 -17.75  -7.613  1 42.648  ? 192 MET A CB   1 ? 
ATOM   2939 C CG   . MET A 1 192 ? -29.159 -19.142 -8.259  1 43.177  ? 192 MET A CG   1 ? 
ATOM   2940 S SD   . MET A 1 192 ? -27.86  -20.133 -7.467  1 47.921  ? 192 MET A SD   1 ? 
ATOM   2941 C CE   . MET A 1 192 ? -26.38  -19.209 -7.888  1 42.812  ? 192 MET A CE   1 ? 
ATOM   2942 H H    . MET A 1 192 ? -32.08  -17.997 -8.698  1 38.795  ? 192 MET A H    1 c 
ATOM   2943 H HA   . MET A 1 192 ? -30.485 -16.045 -7.585  1 40.344  ? 192 MET A HA   1 c 
ATOM   2944 H HB2  . MET A 1 192 ? -28.446 -17.263 -7.771  1 42.278  ? 192 MET A HB2  1 c 
ATOM   2945 H HB3  . MET A 1 192 ? -29.377 -17.862 -6.644  1 42.265  ? 192 MET A HB3  1 c 
ATOM   2946 H HG2  . MET A 1 192 ? -30.011 -19.616 -8.182  1 43.876  ? 192 MET A HG2  1 c 
ATOM   2947 H HG3  . MET A 1 192 ? -28.95  -19.046 -9.209  1 43.883  ? 192 MET A HG3  1 c 
ATOM   2948 H HE1  . MET A 1 192 ? -25.636 -19.826 -8.01   1 44.042  ? 192 MET A HE1  1 c 
ATOM   2949 H HE2  . MET A 1 192 ? -26.531 -18.714 -8.715  1 44.061  ? 192 MET A HE2  1 c 
ATOM   2950 H HE3  . MET A 1 192 ? -26.172 -18.584 -7.169  1 44.042  ? 192 MET A HE3  1 c 
ATOM   2951 N N    . TRP A 1 193 ? -29.369 -15.538 -9.831  1 41.001  ? 193 TRP A N    1 ? 
ATOM   2952 C CA   . TRP A 1 193 ? -28.991 -15.24  -11.2   1 44.448  ? 193 TRP A CA   1 ? 
ATOM   2953 C C    . TRP A 1 193 ? -28.174 -16.404 -11.786 1 49.609  ? 193 TRP A C    1 ? 
ATOM   2954 O O    . TRP A 1 193 ? -27.633 -17.238 -11.038 1 40.974  ? 193 TRP A O    1 ? 
ATOM   2955 C CB   . TRP A 1 193 ? -28.234 -13.912 -11.221 1 47.15   ? 193 TRP A CB   1 ? 
ATOM   2956 C CG   . TRP A 1 193 ? -29.032 -12.806 -10.588 1 54.828  ? 193 TRP A CG   1 ? 
ATOM   2957 C CD1  . TRP A 1 193 ? -28.961 -12.364 -9.3    1 56.995  ? 193 TRP A CD1  1 ? 
ATOM   2958 C CD2  . TRP A 1 193 ? -30.052 -12.013 -11.225 1 52.903  ? 193 TRP A CD2  1 ? 
ATOM   2959 N NE1  . TRP A 1 193 ? -29.851 -11.349 -9.093  1 55.886  ? 193 TRP A NE1  1 ? 
ATOM   2960 C CE2  . TRP A 1 193 ? -30.537 -11.109 -10.251 1 56.523  ? 193 TRP A CE2  1 ? 
ATOM   2961 C CE3  . TRP A 1 193 ? -30.586 -11.968 -12.518 1 50.338  ? 193 TRP A CE3  1 ? 
ATOM   2962 C CZ2  . TRP A 1 193 ? -31.535 -10.175 -10.534 1 53.151  ? 193 TRP A CZ2  1 ? 
ATOM   2963 C CZ3  . TRP A 1 193 ? -31.579 -11.051 -12.798 1 50.509  ? 193 TRP A CZ3  1 ? 
ATOM   2964 C CH2  . TRP A 1 193 ? -32.055 -10.178 -11.812 1 50.191  ? 193 TRP A CH2  1 ? 
ATOM   2965 H H    . TRP A 1 193 ? -28.963 -15.097 -9.141  1 41.584  ? 193 TRP A H    1 c 
ATOM   2966 H HA   . TRP A 1 193 ? -29.816 -15.131 -11.737 1 45.061  ? 193 TRP A HA   1 c 
ATOM   2967 H HB2  . TRP A 1 193 ? -27.391 -14.025 -10.732 1 48.198  ? 193 TRP A HB2  1 c 
ATOM   2968 H HB3  . TRP A 1 193 ? -28.036 -13.675 -12.153 1 48.176  ? 193 TRP A HB3  1 c 
ATOM   2969 H HD1  . TRP A 1 193 ? -28.378 -12.696 -8.648  1 55.971  ? 193 TRP A HD1  1 c 
ATOM   2970 H HE1  . TRP A 1 193 ? -29.964 -10.922 -8.339  1 56.218  ? 193 TRP A HE1  1 c 
ATOM   2971 H HE3  . TRP A 1 193 ? -30.29  -12.563 -13.173 1 50.92   ? 193 TRP A HE3  1 c 
ATOM   2972 H HZ2  . TRP A 1 193 ? -31.854 -9.583  -9.874  1 53.161  ? 193 TRP A HZ2  1 c 
ATOM   2973 H HZ3  . TRP A 1 193 ? -31.955 -11.022 -13.662 1 50.467  ? 193 TRP A HZ3  1 c 
ATOM   2974 H HH2  . TRP A 1 193 ? -32.726 -9.557  -12.034 1 50.999  ? 193 TRP A HH2  1 c 
ATOM   2975 N N    . ASN A 1 194 ? -28.105 -16.447 -13.13  1 44.86   ? 194 ASN A N    1 ? 
ATOM   2976 C CA   . ASN A 1 194 ? -27.478 -17.531 -13.878 1 48.552  ? 194 ASN A CA   1 ? 
ATOM   2977 C C    . ASN A 1 194 ? -25.955 -17.39  -13.963 1 46.89   ? 194 ASN A C    1 ? 
ATOM   2978 O O    . ASN A 1 194 ? -25.271 -18.388 -14.129 1 51.093  ? 194 ASN A O    1 ? 
ATOM   2979 C CB   . ASN A 1 194 ? -27.967 -17.608 -15.323 1 54.409  ? 194 ASN A CB   1 ? 
ATOM   2980 C CG   . ASN A 1 194 ? -27.471 -16.454 -16.17  1 52.944  ? 194 ASN A CG   1 ? 
ATOM   2981 O OD1  . ASN A 1 194 ? -27.966 -15.325 -16.034 1 44.446  ? 194 ASN A OD1  1 ? 
ATOM   2982 N ND2  . ASN A 1 194 ? -26.426 -16.683 -16.957 1 50.31   ? 194 ASN A ND2  1 ? 
ATOM   2983 H H    . ASN A 1 194 ? -28.474 -15.756 -13.602 1 46.824  ? 194 ASN A H    1 c 
ATOM   2984 H HA   . ASN A 1 194 ? -27.697 -18.385 -13.44  1 48.487  ? 194 ASN A HA   1 c 
ATOM   2985 H HB2  . ASN A 1 194 ? -27.663 -18.449 -15.718 1 52.653  ? 194 ASN A HB2  1 c 
ATOM   2986 H HB3  . ASN A 1 194 ? -28.945 -17.611 -15.328 1 52.627  ? 194 ASN A HB3  1 c 
ATOM   2987 H HD21 . ASN A 1 194 ? -25.803 -16.059 -17.056 1 51.071  ? 194 ASN A HD21 1 c 
ATOM   2988 H HD22 . ASN A 1 194 ? -26.353 -17.456 -17.387 1 51.11   ? 194 ASN A HD22 1 c 
ATOM   2989 N N    . ASP A 1 195 ? -25.434 -16.163 -13.864 1 44.766  ? 195 ASP A N    1 ? 
ATOM   2990 C CA   . ASP A 1 195 ? -24.142 -15.784 -14.424 1 47.68   ? 195 ASP A CA   1 ? 
ATOM   2991 C C    . ASP A 1 195 ? -22.944 -16.445 -13.74  1 46.851  ? 195 ASP A C    1 ? 
ATOM   2992 O O    . ASP A 1 195 ? -21.895 -16.535 -14.361 1 48.633  ? 195 ASP A O    1 ? 
ATOM   2993 C CB   . ASP A 1 195 ? -23.957 -14.269 -14.413 1 45.461  ? 195 ASP A CB   1 ? 
ATOM   2994 C CG   . ASP A 1 195 ? -24.168 -13.611 -13.055 1 46.408  ? 195 ASP A CG   1 ? 
ATOM   2995 O OD1  . ASP A 1 195 ? -25.247 -13.857 -12.477 1 45.197  ? 195 ASP A OD1  1 ? 
ATOM   2996 O OD2  . ASP A 1 195 ? -23.264 -12.893 -12.588 1 57.898  ? 195 ASP A OD2  1 ? 
ATOM   2997 H H    . ASP A 1 195 ? -25.914 -15.525 -13.421 1 45.939  ? 195 ASP A H    1 c 
ATOM   2998 H HA   . ASP A 1 195 ? -24.137 -16.058 -15.368 1 46.584  ? 195 ASP A HA   1 c 
ATOM   2999 H HB2  . ASP A 1 195 ? -23.061 -14.052 -14.74  1 46.253  ? 195 ASP A HB2  1 c 
ATOM   3000 H HB3  . ASP A 1 195 ? -24.602 -13.877 -15.038 1 46.191  ? 195 ASP A HB3  1 c 
ATOM   3001 N N    . SER A 1 196 ? -23.015 -16.789 -12.453 1 56.025  ? 196 SER A N    1 ? 
ATOM   3002 C CA   . SER A 1 196 ? -21.802 -17.245 -11.774 1 52.62   ? 196 SER A CA   1 ? 
ATOM   3003 C C    . SER A 1 196 ? -21.772 -18.764 -11.626 1 48.711  ? 196 SER A C    1 ? 
ATOM   3004 O O    . SER A 1 196 ? -20.783 -19.295 -11.117 1 46.55   ? 196 SER A O    1 ? 
ATOM   3005 C CB   . SER A 1 196 ? -21.623 -16.56  -10.453 1 52.116  ? 196 SER A CB   1 ? 
ATOM   3006 O OG   . SER A 1 196 ? -21.564 -15.151 -10.632 1 50.874  ? 196 SER A OG   1 ? 
ATOM   3007 H H    . SER A 1 196 ? -23.8   -16.731 -11.99  1 52.811  ? 196 SER A H    1 c 
ATOM   3008 H HA   . SER A 1 196 ? -21.025 -16.995 -12.333 1 52.348  ? 196 SER A HA   1 c 
ATOM   3009 H HB2  . SER A 1 196 ? -22.367 -16.786 -9.866  1 51.892  ? 196 SER A HB2  1 c 
ATOM   3010 H HB3  . SER A 1 196 ? -20.8   -16.87  -10.035 1 51.838  ? 196 SER A HB3  1 c 
ATOM   3011 N N    . ILE A 1 197 ? -22.827 -19.453 -12.091 1 44.15   ? 197 ILE A N    1 ? 
ATOM   3012 C CA   . ILE A 1 197 ? -22.874 -20.903 -12.019 1 45.298  ? 197 ILE A CA   1 ? 
ATOM   3013 C C    . ILE A 1 197 ? -22.166 -21.472 -13.241 1 52.916  ? 197 ILE A C    1 ? 
ATOM   3014 O O    . ILE A 1 197 ? -22.501 -21.098 -14.362 1 52.782  ? 197 ILE A O    1 ? 
ATOM   3015 C CB   . ILE A 1 197 ? -24.314 -21.42  -11.964 1 45.756  ? 197 ILE A CB   1 ? 
ATOM   3016 C CG1  . ILE A 1 197 ? -25.085 -20.857 -10.801 1 43.292  ? 197 ILE A CG1  1 ? 
ATOM   3017 C CG2  . ILE A 1 197 ? -24.329 -22.948 -11.948 1 49.576  ? 197 ILE A CG2  1 ? 
ATOM   3018 C CD1  . ILE A 1 197 ? -26.59  -20.948 -10.993 1 49.781  ? 197 ILE A CD1  1 ? 
ATOM   3019 H H    . ILE A 1 197 ? -23.535 -19.014 -12.463 1 45.637  ? 197 ILE A H    1 c 
ATOM   3020 H HA   . ILE A 1 197 ? -22.41  -21.197 -11.211 1 46.539  ? 197 ILE A HA   1 c 
ATOM   3021 H HB   . ILE A 1 197 ? -24.76  -21.128 -12.783 1 45.904  ? 197 ILE A HB   1 c 
ATOM   3022 H HG12 . ILE A 1 197 ? -24.838 -21.345 -9.989  1 45.287  ? 197 ILE A HG12 1 c 
ATOM   3023 H HG13 . ILE A 1 197 ? -24.84  -19.918 -10.674 1 45.266  ? 197 ILE A HG13 1 c 
ATOM   3024 H HG21 . ILE A 1 197 ? -25.126 -23.267 -11.494 1 48.394  ? 197 ILE A HG21 1 c 
ATOM   3025 H HG22 . ILE A 1 197 ? -23.543 -23.28  -11.481 1 48.407  ? 197 ILE A HG22 1 c 
ATOM   3026 H HG23 . ILE A 1 197 ? -24.326 -23.284 -12.86  1 48.429  ? 197 ILE A HG23 1 c 
ATOM   3027 H HD11 . ILE A 1 197 ? -26.828 -20.577 -11.864 1 47.742  ? 197 ILE A HD11 1 c 
ATOM   3028 H HD12 . ILE A 1 197 ? -27.043 -20.441 -10.296 1 47.716  ? 197 ILE A HD12 1 c 
ATOM   3029 H HD13 . ILE A 1 197 ? -26.875 -21.879 -10.952 1 47.746  ? 197 ILE A HD13 1 c 
ATOM   3030 N N    . THR A 1 198 ? -21.211 -22.389 -13.014 1 50.749  ? 198 THR A N    1 ? 
ATOM   3031 C CA   . THR A 1 198 ? -20.437 -22.963 -14.107 1 50.253  ? 198 THR A CA   1 ? 
ATOM   3032 C C    . THR A 1 198 ? -20.795 -24.432 -14.255 1 45.909  ? 198 THR A C    1 ? 
ATOM   3033 O O    . THR A 1 198 ? -21.486 -25.004 -13.414 1 45.786  ? 198 THR A O    1 ? 
ATOM   3034 C CB   . THR A 1 198 ? -18.931 -22.784 -13.916 1 48.595  ? 198 THR A CB   1 ? 
ATOM   3035 O OG1  . THR A 1 198 ? -18.547 -23.729 -12.921 1 44.832  ? 198 THR A OG1  1 ? 
ATOM   3036 C CG2  . THR A 1 198 ? -18.574 -21.351 -13.561 1 47.689  ? 198 THR A CG2  1 ? 
ATOM   3037 H H    . THR A 1 198 ? -21.052 -22.678 -12.162 1 51.013  ? 198 THR A H    1 c 
ATOM   3038 H HA   . THR A 1 198 ? -20.687 -22.506 -14.938 1 49.258  ? 198 THR A HA   1 c 
ATOM   3039 H HB   . THR A 1 198 ? -18.474 -23.01  -14.762 1 47.98   ? 198 THR A HB   1 c 
ATOM   3040 H HG21 . THR A 1 198 ? -17.663 -21.318 -13.226 1 47.952  ? 198 THR A HG21 1 c 
ATOM   3041 H HG22 . THR A 1 198 ? -19.179 -21.017 -12.88  1 47.906  ? 198 THR A HG22 1 c 
ATOM   3042 H HG23 . THR A 1 198 ? -18.645 -20.794 -14.355 1 47.945  ? 198 THR A HG23 1 c 
ATOM   3043 N N    . SER A 1 199 ? -20.286 -25.007 -15.347 1 51.422  ? 199 SER A N    1 ? 
ATOM   3044 C CA   . SER A 1 199 ? -20.366 -26.434 -15.613 1 54.357  ? 199 SER A CA   1 ? 
ATOM   3045 C C    . SER A 1 199 ? -19.869 -27.242 -14.414 1 46.596  ? 199 SER A C    1 ? 
ATOM   3046 O O    . SER A 1 199 ? -20.498 -28.229 -14.042 1 46.653  ? 199 SER A O    1 ? 
ATOM   3047 C CB   . SER A 1 199 ? -19.597 -26.78  -16.853 1 56.092  ? 199 SER A CB   1 ? 
ATOM   3048 O OG   . SER A 1 199 ? -20.09  -28.007 -17.36  1 71.508  ? 199 SER A OG   1 ? 
ATOM   3049 H H    . SER A 1 199 ? -19.874 -24.475 -15.965 1 50.736  ? 199 SER A H    1 c 
ATOM   3050 H HA   . SER A 1 199 ? -21.318 -26.663 -15.764 1 52.651  ? 199 SER A HA   1 c 
ATOM   3051 H HB2  . SER A 1 199 ? -19.711 -26.08  -17.522 1 58.811  ? 199 SER A HB2  1 c 
ATOM   3052 H HB3  . SER A 1 199 ? -18.647 -26.864 -16.643 1 58.906  ? 199 SER A HB3  1 c 
ATOM   3053 N N    . GLU A 1 200 ? -18.775 -26.779 -13.784 1 46.695  ? 200 GLU A N    1 ? 
ATOM   3054 C CA   . GLU A 1 200 ? -18.231 -27.399 -12.578 1 46.931  ? 200 GLU A CA   1 ? 
ATOM   3055 C C    . GLU A 1 200 ? -19.25  -27.432 -11.433 1 52.084  ? 200 GLU A C    1 ? 
ATOM   3056 O O    . GLU A 1 200 ? -19.32  -28.421 -10.704 1 52.964  ? 200 GLU A O    1 ? 
ATOM   3057 C CB   . GLU A 1 200 ? -16.962 -26.653 -12.185 1 45.575  ? 200 GLU A CB   1 ? 
ATOM   3058 C CG   . GLU A 1 200 ? -16.272 -27.257 -10.969 1 52.639  ? 200 GLU A CG   1 ? 
ATOM   3059 C CD   . GLU A 1 200 ? -14.982 -26.547 -10.586 1 51.066  ? 200 GLU A CD   1 ? 
ATOM   3060 O OE1  . GLU A 1 200 ? -14.657 -25.507 -11.181 1 51.72   ? 200 GLU A OE1  1 ? 
ATOM   3061 O OE2  . GLU A 1 200 ? -14.303 -27.046 -9.668  1 54.263  ? 200 GLU A OE2  1 ? 
ATOM   3062 H H    . GLU A 1 200 ? -18.34  -26.053 -14.13  1 46.789  ? 200 GLU A H    1 c 
ATOM   3063 H HA   . GLU A 1 200 ? -17.984 -28.333 -12.8   1 47.528  ? 200 GLU A HA   1 c 
ATOM   3064 H HB2  . GLU A 1 200 ? -16.341 -26.656 -12.94  1 47.432  ? 200 GLU A HB2  1 c 
ATOM   3065 H HB3  . GLU A 1 200 ? -17.19  -25.723 -11.992 1 47.408  ? 200 GLU A HB3  1 c 
ATOM   3066 H HG2  . GLU A 1 200 ? -16.879 -27.226 -10.2   1 50.601  ? 200 GLU A HG2  1 c 
ATOM   3067 H HG3  . GLU A 1 200 ? -16.068 -28.2   -11.151 1 50.592  ? 200 GLU A HG3  1 c 
ATOM   3068 N N    . GLY A 1 201 ? -20.04  -26.355 -11.273 1 50.697  ? 201 GLY A N    1 ? 
ATOM   3069 C CA   . GLY A 1 201 ? -20.888 -26.195 -10.102 1 43.736  ? 201 GLY A CA   1 ? 
ATOM   3070 C C    . GLY A 1 201 ? -22.273 -26.813 -10.244 1 42.118  ? 201 GLY A C    1 ? 
ATOM   3071 O O    . GLY A 1 201 ? -22.905 -27.119 -9.244  1 43.929  ? 201 GLY A O    1 ? 
ATOM   3072 H H    . GLY A 1 201 ? -20.036 -25.693 -11.902 1 49.292  ? 201 GLY A H    1 c 
ATOM   3073 H HA2  . GLY A 1 201 ? -20.436 -26.593 -9.321  1 44.998  ? 201 GLY A HA2  1 c 
ATOM   3074 H HA3  . GLY A 1 201 ? -20.99  -25.242 -9.922  1 44.92   ? 201 GLY A HA3  1 c 
ATOM   3075 N N    . ILE A 1 202 ? -22.777 -26.92  -11.474 1 46.248  ? 202 ILE A N    1 ? 
ATOM   3076 C CA   . ILE A 1 202 ? -24.184 -27.205 -11.72  1 49.105  ? 202 ILE A CA   1 ? 
ATOM   3077 C C    . ILE A 1 202 ? -24.607 -28.553 -11.113 1 55.82   ? 202 ILE A C    1 ? 
ATOM   3078 O O    . ILE A 1 202 ? -25.757 -28.722 -10.701 1 50.035  ? 202 ILE A O    1 ? 
ATOM   3079 C CB   . ILE A 1 202 ? -24.471 -27.107 -13.234 1 49.881  ? 202 ILE A CB   1 ? 
ATOM   3080 C CG1  . ILE A 1 202 ? -25.964 -27.186 -13.542 1 52.246  ? 202 ILE A CG1  1 ? 
ATOM   3081 C CG2  . ILE A 1 202 ? -23.684 -28.143 -14.049 1 47.583  ? 202 ILE A CG2  1 ? 
ATOM   3082 C CD1  . ILE A 1 202 ? -26.746 -25.982 -13.085 1 54.234  ? 202 ILE A CD1  1 ? 
ATOM   3083 H H    . ILE A 1 202 ? -22.227 -26.783 -12.189 1 45.919  ? 202 ILE A H    1 c 
ATOM   3084 H HA   . ILE A 1 202 ? -24.701 -26.507 -11.276 1 49.883  ? 202 ILE A HA   1 c 
ATOM   3085 H HB   . ILE A 1 202 ? -24.168 -26.223 -13.524 1 49.757  ? 202 ILE A HB   1 c 
ATOM   3086 H HG12 . ILE A 1 202 ? -26.078 -27.281 -14.51  1 52.097  ? 202 ILE A HG12 1 c 
ATOM   3087 H HG13 . ILE A 1 202 ? -26.339 -27.986 -13.122 1 52.145  ? 202 ILE A HG13 1 c 
ATOM   3088 H HG21 . ILE A 1 202 ? -23.893 -28.039 -14.993 1 48.272  ? 202 ILE A HG21 1 c 
ATOM   3089 H HG22 . ILE A 1 202 ? -23.927 -29.04  -13.765 1 48.291  ? 202 ILE A HG22 1 c 
ATOM   3090 H HG23 . ILE A 1 202 ? -22.738 -28.011 -13.918 1 48.221  ? 202 ILE A HG23 1 c 
ATOM   3091 H HD11 . ILE A 1 202 ? -26.867 -26.018 -12.118 1 53.595  ? 202 ILE A HD11 1 c 
ATOM   3092 H HD12 . ILE A 1 202 ? -27.62  -25.979 -13.52  1 53.621  ? 202 ILE A HD12 1 c 
ATOM   3093 H HD13 . ILE A 1 202 ? -26.265 -25.167 -13.321 1 53.6    ? 202 ILE A HD13 1 c 
ATOM   3094 N N    . ALA A 1 203 ? -23.696 -29.533 -11.067 1 57.454  ? 203 ALA A N    1 ? 
ATOM   3095 C CA   . ALA A 1 203 ? -24.036 -30.848 -10.538 1 55.857  ? 203 ALA A CA   1 ? 
ATOM   3096 C C    . ALA A 1 203 ? -24.249 -30.831 -9.018  1 50.379  ? 203 ALA A C    1 ? 
ATOM   3097 O O    . ALA A 1 203 ? -25.018 -31.631 -8.519  1 50.811  ? 203 ALA A O    1 ? 
ATOM   3098 C CB   . ALA A 1 203 ? -22.965 -31.832 -10.945 1 62.492  ? 203 ALA A CB   1 ? 
ATOM   3099 H H    . ALA A 1 203 ? -22.851 -29.39  -11.386 1 56.517  ? 203 ALA A H    1 c 
ATOM   3100 H HA   . ALA A 1 203 ? -24.895 -31.132 -10.959 1 56.235  ? 203 ALA A HA   1 c 
ATOM   3101 H HB1  . ALA A 1 203 ? -22.894 -31.855 -11.914 1 60.444  ? 203 ALA A HB1  1 c 
ATOM   3102 H HB2  . ALA A 1 203 ? -22.112 -31.562 -10.567 1 60.444  ? 203 ALA A HB2  1 c 
ATOM   3103 H HB3  . ALA A 1 203 ? -23.195 -32.719 -10.619 1 60.444  ? 203 ALA A HB3  1 c 
ATOM   3104 N N    . ASN A 1 204 ? -23.608 -29.915 -8.281  1 50.446  ? 204 ASN A N    1 ? 
ATOM   3105 C CA   . ASN A 1 204 ? -23.761 -29.823 -6.833  1 54.695  ? 204 ASN A CA   1 ? 
ATOM   3106 C C    . ASN A 1 204 ? -24.847 -28.833 -6.396  1 52.688  ? 204 ASN A C    1 ? 
ATOM   3107 O O    . ASN A 1 204 ? -25.128 -28.729 -5.196  1 52.646  ? 204 ASN A O    1 ? 
ATOM   3108 C CB   . ASN A 1 204 ? -22.477 -29.348 -6.151  1 57.916  ? 204 ASN A CB   1 ? 
ATOM   3109 C CG   . ASN A 1 204 ? -21.314 -30.302 -6.289  1 63.8    ? 204 ASN A CG   1 ? 
ATOM   3110 O OD1  . ASN A 1 204 ? -21.447 -31.402 -6.839  1 59.065  ? 204 ASN A OD1  1 ? 
ATOM   3111 N ND2  . ASN A 1 204 ? -20.163 -29.897 -5.775  1 68.824  ? 204 ASN A ND2  1 ? 
ATOM   3112 H H    . ASN A 1 204 ? -23.042 -29.328 -8.694  1 51.427  ? 204 ASN A H    1 c 
ATOM   3113 H HA   . ASN A 1 204 ? -23.979 -30.713 -6.474  1 54.034  ? 204 ASN A HA   1 c 
ATOM   3114 H HB2  . ASN A 1 204 ? -22.22  -28.484 -6.531  1 58.449  ? 204 ASN A HB2  1 c 
ATOM   3115 H HB3  . ASN A 1 204 ? -22.651 -29.212 -5.198  1 58.398  ? 204 ASN A HB3  1 c 
ATOM   3116 H HD21 . ASN A 1 204 ? -19.407 -30.284 -6.029  1 67.094  ? 204 ASN A HD21 1 c 
ATOM   3117 H HD22 . ASN A 1 204 ? -20.147 -29.242 -5.176  1 67.136  ? 204 ASN A HD22 1 c 
ATOM   3118 N N    . LEU A 1 205 ? -25.423 -28.06  -7.326  1 51.427  ? 205 LEU A N    1 ? 
ATOM   3119 C CA   . LEU A 1 205 ? -26.36  -27.007 -6.946  1 44.863  ? 205 LEU A CA   1 ? 
ATOM   3120 C C    . LEU A 1 205 ? -27.731 -27.628 -6.658  1 41.314  ? 205 LEU A C    1 ? 
ATOM   3121 O O    . LEU A 1 205 ? -28.218 -28.465 -7.406  1 43.714  ? 205 LEU A O    1 ? 
ATOM   3122 C CB   . LEU A 1 205 ? -26.4   -25.945 -8.043  1 48.304  ? 205 LEU A CB   1 ? 
ATOM   3123 C CG   . LEU A 1 205 ? -27.335 -24.745 -7.832  1 44.034  ? 205 LEU A CG   1 ? 
ATOM   3124 C CD1  . LEU A 1 205 ? -26.94  -23.929 -6.63   1 44.842  ? 205 LEU A CD1  1 ? 
ATOM   3125 C CD2  . LEU A 1 205 ? -27.328 -23.889 -9.081  1 44.129  ? 205 LEU A CD2  1 ? 
ATOM   3126 H H    . LEU A 1 205 ? -25.239 -28.189 -8.211  1 50.152  ? 205 LEU A H    1 c 
ATOM   3127 H HA   . LEU A 1 205 ? -26.023 -26.583 -6.116  1 46.099  ? 205 LEU A HA   1 c 
ATOM   3128 H HB2  . LEU A 1 205 ? -25.485 -25.603 -8.167  1 46.514  ? 205 LEU A HB2  1 c 
ATOM   3129 H HB3  . LEU A 1 205 ? -26.653 -26.388 -8.885  1 46.541  ? 205 LEU A HB3  1 c 
ATOM   3130 H HG   . LEU A 1 205 ? -28.257 -25.082 -7.693  1 44.938  ? 205 LEU A HG   1 c 
ATOM   3131 H HD11 . LEU A 1 205 ? -27.124 -24.434 -5.82   1 44.603  ? 205 LEU A HD11 1 c 
ATOM   3132 H HD12 . LEU A 1 205 ? -27.45  -23.101 -6.617  1 44.613  ? 205 LEU A HD12 1 c 
ATOM   3133 H HD13 . LEU A 1 205 ? -25.992 -23.723 -6.674  1 44.603  ? 205 LEU A HD13 1 c 
ATOM   3134 H HD21 . LEU A 1 205 ? -27.623 -24.419 -9.84   1 44.118  ? 205 LEU A HD21 1 c 
ATOM   3135 H HD22 . LEU A 1 205 ? -26.428 -23.561 -9.247  1 44.105  ? 205 LEU A HD22 1 c 
ATOM   3136 H HD23 . LEU A 1 205 ? -27.93  -23.134 -8.962  1 44.108  ? 205 LEU A HD23 1 c 
ATOM   3137 N N    . ASP A 1 206 ? -28.307 -27.256 -5.511  1 49.011  ? 206 ASP A N    1 ? 
ATOM   3138 C CA   . ASP A 1 206 ? -29.658 -27.629 -5.115  1 49.862  ? 206 ASP A CA   1 ? 
ATOM   3139 C C    . ASP A 1 206 ? -30.619 -27.192 -6.213  1 56.044  ? 206 ASP A C    1 ? 
ATOM   3140 O O    . ASP A 1 206 ? -30.622 -26.031 -6.62   1 54.012  ? 206 ASP A O    1 ? 
ATOM   3141 C CB   . ASP A 1 206 ? -29.996 -26.992 -3.777  1 51.443  ? 206 ASP A CB   1 ? 
ATOM   3142 C CG   . ASP A 1 206 ? -31.305 -27.414 -3.125  1 53.121  ? 206 ASP A CG   1 ? 
ATOM   3143 O OD1  . ASP A 1 206 ? -32.152 -28.022 -3.823  1 46.981  ? 206 ASP A OD1  1 ? 
ATOM   3144 O OD2  . ASP A 1 206 ? -31.448 -27.149 -1.905  1 54.873  ? 206 ASP A OD2  1 ? 
ATOM   3145 H H    . ASP A 1 206 ? -27.825 -26.733 -4.936  1 47.28   ? 206 ASP A H    1 c 
ATOM   3146 H HA   . ASP A 1 206 ? -29.692 -28.607 -5.016  1 51.176  ? 206 ASP A HA   1 c 
ATOM   3147 H HB2  . ASP A 1 206 ? -29.276 -27.2   -3.145  1 51.428  ? 206 ASP A HB2  1 c 
ATOM   3148 H HB3  . ASP A 1 206 ? -30.017 -26.019 -3.894  1 51.45   ? 206 ASP A HB3  1 c 
ATOM   3149 N N    . ASP A 1 207 ? -31.424 -28.145 -6.684  1 61.211  ? 207 ASP A N    1 ? 
ATOM   3150 C CA   . ASP A 1 207 ? -32.219 -27.975 -7.889  1 65.719  ? 207 ASP A CA   1 ? 
ATOM   3151 C C    . ASP A 1 207 ? -33.614 -27.488 -7.504  1 60.944  ? 207 ASP A C    1 ? 
ATOM   3152 O O    . ASP A 1 207 ? -34.485 -27.381 -8.364  1 59.494  ? 207 ASP A O    1 ? 
ATOM   3153 C CB   . ASP A 1 207 ? -32.182 -29.23  -8.751  1 67.569  ? 207 ASP A CB   1 ? 
ATOM   3154 C CG   . ASP A 1 207 ? -32.505 -30.513 -8.007  1 68.24   ? 207 ASP A CG   1 ? 
ATOM   3155 O OD1  . ASP A 1 207 ? -33.583 -30.555 -7.393  1 67.919  ? 207 ASP A OD1  1 ? 
ATOM   3156 O OD2  . ASP A 1 207 ? -31.63  -31.418 -7.967  1 85.401  ? 207 ASP A OD2  1 ? 
ATOM   3157 H H    . ASP A 1 207 ? -31.487 -28.933 -6.227  1 60.759  ? 207 ASP A H    1 c 
ATOM   3158 H HA   . ASP A 1 207 ? -31.804 -27.277 -8.433  1 64.103  ? 207 ASP A HA   1 c 
ATOM   3159 H HB2  . ASP A 1 207 ? -32.821 -29.133 -9.488  1 67.273  ? 207 ASP A HB2  1 c 
ATOM   3160 H HB3  . ASP A 1 207 ? -31.287 -29.315 -9.141  1 67.388  ? 207 ASP A HB3  1 c 
ATOM   3161 N N    . SER A 1 208 ? -33.8   -27.237 -6.202  1 58.161  ? 208 SER A N    1 ? 
ATOM   3162 C CA   . SER A 1 208 ? -34.827 -26.353 -5.689  1 58.15   ? 208 SER A CA   1 ? 
ATOM   3163 C C    . SER A 1 208 ? -34.687 -24.933 -6.247  1 59.156  ? 208 SER A C    1 ? 
ATOM   3164 O O    . SER A 1 208 ? -35.686 -24.225 -6.349  1 54.694  ? 208 SER A O    1 ? 
ATOM   3165 C CB   . SER A 1 208 ? -34.793 -26.331 -4.184  1 61.793  ? 208 SER A CB   1 ? 
ATOM   3166 O OG   . SER A 1 208 ? -35.053 -27.621 -3.653  1 66.456  ? 208 SER A OG   1 ? 
ATOM   3167 H H    . SER A 1 208 ? -33.293 -27.688 -5.592  1 58.89   ? 208 SER A H    1 c 
ATOM   3168 H HA   . SER A 1 208 ? -35.707 -26.709 -5.975  1 58.997  ? 208 SER A HA   1 c 
ATOM   3169 H HB2  . SER A 1 208 ? -33.916 -26.025 -3.885  1 61.919  ? 208 SER A HB2  1 c 
ATOM   3170 H HB3  . SER A 1 208 ? -35.464 -25.703 -3.855  1 61.978  ? 208 SER A HB3  1 c 
ATOM   3171 N N    . PHE A 1 209 ? -33.457 -24.5   -6.566  1 55.272  ? 209 PHE A N    1 ? 
ATOM   3172 C CA   . PHE A 1 209 ? -33.253 -23.188 -7.152  1 51.416  ? 209 PHE A CA   1 ? 
ATOM   3173 C C    . PHE A 1 209 ? -33.945 -23.111 -8.509  1 54.653  ? 209 PHE A C    1 ? 
ATOM   3174 O O    . PHE A 1 209 ? -33.805 -24.035 -9.307  1 50.094  ? 209 PHE A O    1 ? 
ATOM   3175 C CB   . PHE A 1 209 ? -31.789 -22.832 -7.411  1 47.977  ? 209 PHE A CB   1 ? 
ATOM   3176 C CG   . PHE A 1 209 ? -31.045 -22.235 -6.229  1 45.177  ? 209 PHE A CG   1 ? 
ATOM   3177 C CD1  . PHE A 1 209 ? -31.245 -20.906 -5.867  1 44.228  ? 209 PHE A CD1  1 ? 
ATOM   3178 C CD2  . PHE A 1 209 ? -30.12  -22.985 -5.511  1 49.169  ? 209 PHE A CD2  1 ? 
ATOM   3179 C CE1  . PHE A 1 209 ? -30.55  -20.342 -4.812  1 47.546  ? 209 PHE A CE1  1 ? 
ATOM   3180 C CE2  . PHE A 1 209 ? -29.413 -22.411 -4.457  1 51.481  ? 209 PHE A CE2  1 ? 
ATOM   3181 C CZ   . PHE A 1 209 ? -29.636 -21.097 -4.101  1 49.56   ? 209 PHE A CZ   1 ? 
ATOM   3182 H H    . PHE A 1 209 ? -32.728 -25.021 -6.389  1 55.222  ? 209 PHE A H    1 c 
ATOM   3183 H HA   . PHE A 1 209 ? -33.641 -22.511 -6.549  1 51.845  ? 209 PHE A HA   1 c 
ATOM   3184 H HB2  . PHE A 1 209 ? -31.32  -23.646 -7.7    1 48.162  ? 209 PHE A HB2  1 c 
ATOM   3185 H HB3  . PHE A 1 209 ? -31.75  -22.191 -8.157  1 48.125  ? 209 PHE A HB3  1 c 
ATOM   3186 H HD1  . PHE A 1 209 ? -31.865 -20.385 -6.35   1 45.233  ? 209 PHE A HD1  1 c 
ATOM   3187 H HD2  . PHE A 1 209 ? -29.955 -23.88  -5.752  1 48.738  ? 209 PHE A HD2  1 c 
ATOM   3188 H HE1  . PHE A 1 209 ? -30.706 -19.442 -4.574  1 47.235  ? 209 PHE A HE1  1 c 
ATOM   3189 H HE2  . PHE A 1 209 ? -28.795 -22.932 -3.969  1 50.387  ? 209 PHE A HE2  1 c 
ATOM   3190 H HZ   . PHE A 1 209 ? -29.166 -20.715 -3.377  1 49.449  ? 209 PHE A HZ   1 c 
ATOM   3191 N N    . SER A 1 210 ? -34.702 -22.022 -8.745  1 43.505  ? 210 SER A N    1 ? 
ATOM   3192 C CA   . SER A 1 210 ? -34.975 -21.572 -10.106 1 43.299  ? 210 SER A CA   1 ? 
ATOM   3193 C C    . SER A 1 210 ? -34.002 -20.452 -10.458 1 38.116  ? 210 SER A C    1 ? 
ATOM   3194 O O    . SER A 1 210 ? -33.418 -19.82  -9.575  1 44.931  ? 210 SER A O    1 ? 
ATOM   3195 C CB   . SER A 1 210 ? -36.42  -21.177 -10.308 1 45.856  ? 210 SER A CB   1 ? 
ATOM   3196 O OG   . SER A 1 210 ? -36.831 -20.211 -9.354  1 46.081  ? 210 SER A OG   1 ? 
ATOM   3197 H H    . SER A 1 210 ? -35.059 -21.556 -8.044  1 45.98   ? 210 SER A H    1 c 
ATOM   3198 H HA   . SER A 1 210 ? -34.789 -22.326 -10.718 1 42.889  ? 210 SER A HA   1 c 
ATOM   3199 H HB2  . SER A 1 210 ? -36.532 -20.812 -11.207 1 45.318  ? 210 SER A HB2  1 c 
ATOM   3200 H HB3  . SER A 1 210 ? -36.985 -21.969 -10.23  1 45.318  ? 210 SER A HB3  1 c 
ATOM   3201 N N    . ILE A 1 211 ? -33.764 -20.275 -11.755 1 40.958  ? 211 ILE A N    1 ? 
ATOM   3202 C CA   . ILE A 1 211 ? -32.684 -19.425 -12.234 1 41.255  ? 211 ILE A CA   1 ? 
ATOM   3203 C C    . ILE A 1 211 ? -33.255 -18.228 -12.989 1 46.749  ? 211 ILE A C    1 ? 
ATOM   3204 O O    . ILE A 1 211 ? -34.157 -18.362 -13.822 1 43.191  ? 211 ILE A O    1 ? 
ATOM   3205 C CB   . ILE A 1 211 ? -31.705 -20.219 -13.113 1 44.034  ? 211 ILE A CB   1 ? 
ATOM   3206 C CG1  . ILE A 1 211 ? -31.196 -21.486 -12.399 1 43.253  ? 211 ILE A CG1  1 ? 
ATOM   3207 C CG2  . ILE A 1 211 ? -30.546 -19.341 -13.591 1 48.332  ? 211 ILE A CG2  1 ? 
ATOM   3208 C CD1  . ILE A 1 211 ? -30.49  -21.234 -11.079 1 42.258  ? 211 ILE A CD1  1 ? 
ATOM   3209 H H    . ILE A 1 211 ? -34.295 -20.696 -12.369 1 40.366  ? 211 ILE A H    1 c 
ATOM   3210 H HA   . ILE A 1 211 ? -32.189 -19.096 -11.464 1 42.7    ? 211 ILE A HA   1 c 
ATOM   3211 H HB   . ILE A 1 211 ? -32.198 -20.511 -13.904 1 44.143  ? 211 ILE A HB   1 c 
ATOM   3212 H HG12 . ILE A 1 211 ? -31.955 -22.083 -12.238 1 43.189  ? 211 ILE A HG12 1 c 
ATOM   3213 H HG13 . ILE A 1 211 ? -30.579 -21.952 -12.997 1 43.225  ? 211 ILE A HG13 1 c 
ATOM   3214 H HG21 . ILE A 1 211 ? -29.769 -19.895 -13.776 1 46.964  ? 211 ILE A HG21 1 c 
ATOM   3215 H HG22 . ILE A 1 211 ? -30.321 -18.692 -12.903 1 46.952  ? 211 ILE A HG22 1 c 
ATOM   3216 H HG23 . ILE A 1 211 ? -30.805 -18.872 -14.403 1 47.001  ? 211 ILE A HG23 1 c 
ATOM   3217 H HD11 . ILE A 1 211 ? -29.842 -20.511 -11.177 1 42.572  ? 211 ILE A HD11 1 c 
ATOM   3218 H HD12 . ILE A 1 211 ? -30.025 -22.047 -10.805 1 42.552  ? 211 ILE A HD12 1 c 
ATOM   3219 H HD13 . ILE A 1 211 ? -31.143 -20.992 -10.396 1 42.54   ? 211 ILE A HD13 1 c 
ATOM   3220 N N    . LEU A 1 212 ? -32.673 -17.066 -12.666 1 43.704  ? 212 LEU A N    1 ? 
ATOM   3221 C CA   . LEU A 1 212 ? -32.953 -15.809 -13.314 1 44.127  ? 212 LEU A CA   1 ? 
ATOM   3222 C C    . LEU A 1 212 ? -31.913 -15.635 -14.403 1 42.408  ? 212 LEU A C    1 ? 
ATOM   3223 O O    . LEU A 1 212 ? -30.798 -15.163 -14.139 1 40.772  ? 212 LEU A O    1 ? 
ATOM   3224 C CB   . LEU A 1 212 ? -32.902 -14.661 -12.296 1 45.025  ? 212 LEU A CB   1 ? 
ATOM   3225 C CG   . LEU A 1 212 ? -33.809 -14.768 -11.066 1 45.175  ? 212 LEU A CG   1 ? 
ATOM   3226 C CD1  . LEU A 1 212 ? -33.947 -13.396 -10.434 1 50.267  ? 212 LEU A CD1  1 ? 
ATOM   3227 C CD2  . LEU A 1 212 ? -35.195 -15.335 -11.359 1 45.967  ? 212 LEU A CD2  1 ? 
ATOM   3228 H H    . LEU A 1 212 ? -32.054 -17.063 -11.993 1 44.468  ? 212 LEU A H    1 c 
ATOM   3229 H HA   . LEU A 1 212 ? -33.854 -15.847 -13.722 1 43.91   ? 212 LEU A HA   1 c 
ATOM   3230 H HB2  . LEU A 1 212 ? -31.976 -14.571 -11.981 1 44.827  ? 212 LEU A HB2  1 c 
ATOM   3231 H HB3  . LEU A 1 212 ? -33.124 -13.827 -12.772 1 44.899  ? 212 LEU A HB3  1 c 
ATOM   3232 H HG   . LEU A 1 212 ? -33.368 -15.365 -10.409 1 46.207  ? 212 LEU A HG   1 c 
ATOM   3233 H HD11 . LEU A 1 212 ? -33.064 -13.03  -10.255 1 48.68   ? 212 LEU A HD11 1 c 
ATOM   3234 H HD12 . LEU A 1 212 ? -34.439 -13.471 -9.601  1 48.652  ? 212 LEU A HD12 1 c 
ATOM   3235 H HD13 . LEU A 1 212 ? -34.424 -12.804 -11.04  1 48.634  ? 212 LEU A HD13 1 c 
ATOM   3236 H HD21 . LEU A 1 212 ? -35.151 -16.306 -11.375 1 45.734  ? 212 LEU A HD21 1 c 
ATOM   3237 H HD22 . LEU A 1 212 ? -35.502 -15.013 -12.222 1 45.704  ? 212 LEU A HD22 1 c 
ATOM   3238 H HD23 . LEU A 1 212 ? -35.818 -15.052 -10.669 1 45.769  ? 212 LEU A HD23 1 c 
ATOM   3239 N N    . TYR A 1 213 ? -32.309 -15.971 -15.634 1 43.691  ? 213 TYR A N    1 ? 
ATOM   3240 C CA   . TYR A 1 213 ? -31.358 -16.022 -16.724 1 43.678  ? 213 TYR A CA   1 ? 
ATOM   3241 C C    . TYR A 1 213 ? -31.323 -14.682 -17.451 1 48.362  ? 213 TYR A C    1 ? 
ATOM   3242 O O    . TYR A 1 213 ? -32.258 -14.296 -18.175 1 42.233  ? 213 TYR A O    1 ? 
ATOM   3243 C CB   . TYR A 1 213 ? -31.702 -17.202 -17.626 1 46.442  ? 213 TYR A CB   1 ? 
ATOM   3244 C CG   . TYR A 1 213 ? -30.504 -17.576 -18.482 1 46.182  ? 213 TYR A CG   1 ? 
ATOM   3245 C CD1  . TYR A 1 213 ? -30.114 -16.773 -19.547 1 45.387  ? 213 TYR A CD1  1 ? 
ATOM   3246 C CD2  . TYR A 1 213 ? -29.752 -18.721 -18.221 1 44.771  ? 213 TYR A CD2  1 ? 
ATOM   3247 C CE1  . TYR A 1 213 ? -29.01  -17.093 -20.324 1 47.986  ? 213 TYR A CE1  1 ? 
ATOM   3248 C CE2  . TYR A 1 213 ? -28.664 -19.063 -19.014 1 45.326  ? 213 TYR A CE2  1 ? 
ATOM   3249 C CZ   . TYR A 1 213 ? -28.285 -18.243 -20.062 1 45.383  ? 213 TYR A CZ   1 ? 
ATOM   3250 O OH   . TYR A 1 213 ? -27.219 -18.53  -20.855 1 49.2    ? 213 TYR A OH   1 ? 
ATOM   3251 H H    . TYR A 1 213 ? -33.186 -16.168 -15.8   1 43.408  ? 213 TYR A H    1 c 
ATOM   3252 H HA   . TYR A 1 213 ? -30.459 -16.194 -16.342 1 45.021  ? 213 TYR A HA   1 c 
ATOM   3253 H HB2  . TYR A 1 213 ? -31.959 -17.97  -17.068 1 45.724  ? 213 TYR A HB2  1 c 
ATOM   3254 H HB3  . TYR A 1 213 ? -32.457 -16.958 -18.206 1 45.72   ? 213 TYR A HB3  1 c 
ATOM   3255 H HD1  . TYR A 1 213 ? -30.599 -15.988 -19.739 1 46.174  ? 213 TYR A HD1  1 c 
ATOM   3256 H HD2  . TYR A 1 213 ? -30.001 -19.288 -17.509 1 45.253  ? 213 TYR A HD2  1 c 
ATOM   3257 H HE1  . TYR A 1 213 ? -28.766 -16.539 -21.046 1 46.751  ? 213 TYR A HE1  1 c 
ATOM   3258 H HE2  . TYR A 1 213 ? -28.166 -19.839 -18.822 1 45.258  ? 213 TYR A HE2  1 c 
ATOM   3259 N N    . TRP A 1 214 ? -30.211 -13.971 -17.276 1 43.921  ? 214 TRP A N    1 ? 
ATOM   3260 C CA   . TRP A 1 214 ? -30.18  -12.608 -17.77  1 50.052  ? 214 TRP A CA   1 ? 
ATOM   3261 C C    . TRP A 1 214 ? -29.138 -12.449 -18.858 1 52.477  ? 214 TRP A C    1 ? 
ATOM   3262 O O    . TRP A 1 214 ? -29.322 -11.631 -19.758 1 52.171  ? 214 TRP A O    1 ? 
ATOM   3263 C CB   . TRP A 1 214 ? -29.995 -11.61  -16.624 1 46.688  ? 214 TRP A CB   1 ? 
ATOM   3264 C CG   . TRP A 1 214 ? -28.676 -11.672 -15.923 1 44.936  ? 214 TRP A CG   1 ? 
ATOM   3265 C CD1  . TRP A 1 214 ? -28.33  -12.562 -14.956 1 44.541  ? 214 TRP A CD1  1 ? 
ATOM   3266 C CD2  . TRP A 1 214 ? -27.566 -10.757 -16.06  1 47.475  ? 214 TRP A CD2  1 ? 
ATOM   3267 N NE1  . TRP A 1 214 ? -27.057 -12.31  -14.532 1 48.384  ? 214 TRP A NE1  1 ? 
ATOM   3268 C CE2  . TRP A 1 214 ? -26.561 -11.209 -15.182 1 48.194  ? 214 TRP A CE2  1 ? 
ATOM   3269 C CE3  . TRP A 1 214 ? -27.305 -9.63   -16.844 1 48.997  ? 214 TRP A CE3  1 ? 
ATOM   3270 C CZ2  . TRP A 1 214 ? -25.327 -10.566 -15.058 1 53.465  ? 214 TRP A CZ2  1 ? 
ATOM   3271 C CZ3  . TRP A 1 214 ? -26.093 -8.977  -16.703 1 52.663  ? 214 TRP A CZ3  1 ? 
ATOM   3272 C CH2  . TRP A 1 214 ? -25.122 -9.431  -15.811 1 52.681  ? 214 TRP A CH2  1 ? 
ATOM   3273 H H    . TRP A 1 214 ? -29.497 -14.311 -16.818 1 46.326  ? 214 TRP A H    1 c 
ATOM   3274 H HA   . TRP A 1 214 ? -31.06  -12.408 -18.181 1 48.495  ? 214 TRP A HA   1 c 
ATOM   3275 H HB2  . TRP A 1 214 ? -30.118 -10.705 -16.983 1 47.016  ? 214 TRP A HB2  1 c 
ATOM   3276 H HB3  . TRP A 1 214 ? -30.708 -11.76  -15.967 1 47.011  ? 214 TRP A HB3  1 c 
ATOM   3277 H HD1  . TRP A 1 214 ? -28.855 -13.288 -14.664 1 45.588  ? 214 TRP A HD1  1 c 
ATOM   3278 H HE1  . TRP A 1 214 ? -26.636 -12.773 -13.928 1 47.408  ? 214 TRP A HE1  1 c 
ATOM   3279 H HE3  . TRP A 1 214 ? -27.957 -9.303  -17.436 1 49.474  ? 214 TRP A HE3  1 c 
ATOM   3280 H HZ2  . TRP A 1 214 ? -24.68  -10.87  -14.445 1 51.968  ? 214 TRP A HZ2  1 c 
ATOM   3281 H HZ3  . TRP A 1 214 ? -25.916 -8.214  -17.228 1 51.734  ? 214 TRP A HZ3  1 c 
ATOM   3282 H HH2  . TRP A 1 214 ? -24.297 -8.982  -15.755 1 52.758  ? 214 TRP A HH2  1 c 
ATOM   3283 N N    . GLN A 1 215 ? -28.059 -13.229 -18.774 1 52.805  ? 215 GLN A N    1 ? 
ATOM   3284 C CA   . GLN A 1 215 ? -26.975 -13.086 -19.726 1 52.561  ? 215 GLN A CA   1 ? 
ATOM   3285 C C    . GLN A 1 215 ? -26.079 -14.309 -19.63  1 50.887  ? 215 GLN A C    1 ? 
ATOM   3286 O O    . GLN A 1 215 ? -25.593 -14.639 -18.553 1 47.012  ? 215 GLN A O    1 ? 
ATOM   3287 C CB   . GLN A 1 215 ? -26.15  -11.834 -19.451 1 53.451  ? 215 GLN A CB   1 ? 
ATOM   3288 C CG   . GLN A 1 215 ? -25.034 -11.606 -20.462 1 59.905  ? 215 GLN A CG   1 ? 
ATOM   3289 C CD   . GLN A 1 215 ? -24.317 -10.296 -20.245 1 59.549  ? 215 GLN A CD   1 ? 
ATOM   3290 O OE1  . GLN A 1 215 ? -23.629 -10.101 -19.241 1 68.586  ? 215 GLN A OE1  1 ? 
ATOM   3291 N NE2  . GLN A 1 215 ? -24.483 -9.375  -21.178 1 74.873  ? 215 GLN A NE2  1 ? 
ATOM   3292 H H    . GLN A 1 215 ? -27.977 -13.842 -18.104 1 52.501  ? 215 GLN A H    1 c 
ATOM   3293 H HA   . GLN A 1 215 ? -27.359 -13.03  -20.638 1 52.463  ? 215 GLN A HA   1 c 
ATOM   3294 H HB2  . GLN A 1 215 ? -26.742 -11.054 -19.454 1 54.628  ? 215 GLN A HB2  1 c 
ATOM   3295 H HB3  . GLN A 1 215 ? -25.758 -11.906 -18.556 1 54.644  ? 215 GLN A HB3  1 c 
ATOM   3296 H HG2  . GLN A 1 215 ? -24.378 -12.332 -20.397 1 58.255  ? 215 GLN A HG2  1 c 
ATOM   3297 H HG3  . GLN A 1 215 ? -25.408 -11.621 -21.369 1 58.378  ? 215 GLN A HG3  1 c 
ATOM   3298 H HE21 . GLN A 1 215 ? -23.784 -9.08   -21.638 1 69.762  ? 215 GLN A HE21 1 c 
ATOM   3299 H HE22 . GLN A 1 215 ? -25.293 -9.052  -21.342 1 69.743  ? 215 GLN A HE22 1 c 
ATOM   3300 N N    . GLN A 1 216 ? -25.883 -14.958 -20.776 1 53.254  ? 216 GLN A N    1 ? 
ATOM   3301 C CA   . GLN A 1 216 ? -25.024 -16.118 -20.861 1 53.131  ? 216 GLN A CA   1 ? 
ATOM   3302 C C    . GLN A 1 216 ? -23.611 -15.623 -20.608 1 53.469  ? 216 GLN A C    1 ? 
ATOM   3303 O O    . GLN A 1 216 ? -23.205 -14.63  -21.217 1 53.41   ? 216 GLN A O    1 ? 
ATOM   3304 C CB   . GLN A 1 216 ? -25.152 -16.76  -22.241 1 54.768  ? 216 GLN A CB   1 ? 
ATOM   3305 C CG   . GLN A 1 216 ? -24.245 -17.969 -22.456 1 60.584  ? 216 GLN A CG   1 ? 
ATOM   3306 C CD   . GLN A 1 216 ? -24.526 -18.715 -23.746 1 60.118  ? 216 GLN A CD   1 ? 
ATOM   3307 O OE1  . GLN A 1 216 ? -25.142 -18.195 -24.686 1 64.146  ? 216 GLN A OE1  1 ? 
ATOM   3308 N NE2  . GLN A 1 216 ? -24.108 -19.972 -23.786 1 50.614  ? 216 GLN A NE2  1 ? 
ATOM   3309 H H    . GLN A 1 216 ? -26.3   -14.667 -21.536 1 52.687  ? 216 GLN A H    1 c 
ATOM   3310 H HA   . GLN A 1 216 ? -25.287 -16.764 -20.158 1 53.437  ? 216 GLN A HA   1 c 
ATOM   3311 H HB2  . GLN A 1 216 ? -26.082 -17.028 -22.383 1 55.624  ? 216 GLN A HB2  1 c 
ATOM   3312 H HB3  . GLN A 1 216 ? -24.939 -16.082 -22.915 1 55.715  ? 216 GLN A HB3  1 c 
ATOM   3313 H HG2  . GLN A 1 216 ? -23.31  -17.678 -22.463 1 59.238  ? 216 GLN A HG2  1 c 
ATOM   3314 H HG3  . GLN A 1 216 ? -24.356 -18.591 -21.706 1 59.135  ? 216 GLN A HG3  1 c 
ATOM   3315 H HE21 . GLN A 1 216 ? -24.501 -20.551 -24.332 1 53.487  ? 216 GLN A HE21 1 c 
ATOM   3316 H HE22 . GLN A 1 216 ? -23.437 -20.236 -23.268 1 53.573  ? 216 GLN A HE22 1 c 
ATOM   3317 N N    . SER A 1 217 ? -22.881 -16.315 -19.72  1 52.761  ? 217 SER A N    1 ? 
ATOM   3318 C CA   . SER A 1 217 ? -21.53  -15.9   -19.374 1 51.078  ? 217 SER A CA   1 ? 
ATOM   3319 C C    . SER A 1 217 ? -20.511 -16.563 -20.298 1 47.701  ? 217 SER A C    1 ? 
ATOM   3320 O O    . SER A 1 217 ? -20.78  -17.588 -20.922 1 47.391  ? 217 SER A O    1 ? 
ATOM   3321 C CB   . SER A 1 217 ? -21.231 -16.196 -17.928 1 54.009  ? 217 SER A CB   1 ? 
ATOM   3322 O OG   . SER A 1 217 ? -22.174 -15.576 -17.07  1 51.471  ? 217 SER A OG   1 ? 
ATOM   3323 H H    . SER A 1 217 ? -23.229 -17.063 -19.326 1 52.565  ? 217 SER A H    1 c 
ATOM   3324 H HA   . SER A 1 217 ? -21.466 -14.919 -19.501 1 51.325  ? 217 SER A HA   1 c 
ATOM   3325 H HB2  . SER A 1 217 ? -21.25  -17.162 -17.787 1 52.722  ? 217 SER A HB2  1 c 
ATOM   3326 H HB3  . SER A 1 217 ? -20.335 -15.874 -17.712 1 52.722  ? 217 SER A HB3  1 c 
ATOM   3327 N N    . THR A 1 218 ? -19.329 -15.954 -20.354 1 51.782  ? 218 THR A N    1 ? 
ATOM   3328 C CA   . THR A 1 218 ? -18.165 -16.538 -20.995 1 60.476  ? 218 THR A CA   1 ? 
ATOM   3329 C C    . THR A 1 218 ? -17.169 -16.931 -19.903 1 56.071  ? 218 THR A C    1 ? 
ATOM   3330 O O    . THR A 1 218 ? -16.805 -16.095 -19.086 1 58.507  ? 218 THR A O    1 ? 
ATOM   3331 C CB   . THR A 1 218 ? -17.578 -15.51  -21.969 1 65.328  ? 218 THR A CB   1 ? 
ATOM   3332 O OG1  . THR A 1 218 ? -18.63  -15.198 -22.879 1 70.498  ? 218 THR A OG1  1 ? 
ATOM   3333 C CG2  . THR A 1 218 ? -16.385 -16.042 -22.748 1 63.536  ? 218 THR A CG2  1 ? 
ATOM   3334 H H    . THR A 1 218 ? -19.24  -15.129 -19.971 1 52.584  ? 218 THR A H    1 c 
ATOM   3335 H HA   . THR A 1 218 ? -18.433 -17.336 -21.498 1 58.513  ? 218 THR A HA   1 c 
ATOM   3336 H HB   . THR A 1 218 ? -17.315 -14.695 -21.478 1 65.063  ? 218 THR A HB   1 c 
ATOM   3337 H HG21 . THR A 1 218 ? -16.255 -15.505 -23.548 1 64.042  ? 218 THR A HG21 1 c 
ATOM   3338 H HG22 . THR A 1 218 ? -16.547 -16.965 -23.003 1 64.024  ? 218 THR A HG22 1 c 
ATOM   3339 H HG23 . THR A 1 218 ? -15.588 -15.995 -22.195 1 64.006  ? 218 THR A HG23 1 c 
ATOM   3340 N N    . LEU A 1 219 ? -16.703 -18.185 -19.917 1 55.552  ? 219 LEU A N    1 ? 
ATOM   3341 C CA   . LEU A 1 219 ? -15.657 -18.637 -19.007 1 55.89   ? 219 LEU A CA   1 ? 
ATOM   3342 C C    . LEU A 1 219 ? -14.347 -17.939 -19.368 1 59.856  ? 219 LEU A C    1 ? 
ATOM   3343 O O    . LEU A 1 219 ? -14.194 -17.473 -20.492 1 62.423  ? 219 LEU A O    1 ? 
ATOM   3344 C CB   . LEU A 1 219 ? -15.502 -20.159 -19.08  1 53.972  ? 219 LEU A CB   1 ? 
ATOM   3345 C CG   . LEU A 1 219 ? -16.75  -20.985 -18.749 1 59.519  ? 219 LEU A CG   1 ? 
ATOM   3346 C CD1  . LEU A 1 219 ? -16.451 -22.481 -18.874 1 67.79   ? 219 LEU A CD1  1 ? 
ATOM   3347 C CD2  . LEU A 1 219 ? -17.285 -20.668 -17.37  1 53.82   ? 219 LEU A CD2  1 ? 
ATOM   3348 H H    . LEU A 1 219 ? -17.038 -18.778 -20.526 1 55.834  ? 219 LEU A H    1 c 
ATOM   3349 H HA   . LEU A 1 219 ? -15.909 -18.378 -18.084 1 56.174  ? 219 LEU A HA   1 c 
ATOM   3350 H HB2  . LEU A 1 219 ? -15.209 -20.393 -19.991 1 55.626  ? 219 LEU A HB2  1 c 
ATOM   3351 H HB3  . LEU A 1 219 ? -14.783 -20.424 -18.462 1 55.626  ? 219 LEU A HB3  1 c 
ATOM   3352 H HG   . LEU A 1 219 ? -17.455 -20.76  -19.409 1 58.727  ? 219 LEU A HG   1 c 
ATOM   3353 H HD11 . LEU A 1 219 ? -16.113 -22.672 -19.765 1 65.232  ? 219 LEU A HD11 1 c 
ATOM   3354 H HD12 . LEU A 1 219 ? -17.266 -22.989 -18.723 1 65.178  ? 219 LEU A HD12 1 c 
ATOM   3355 H HD13 . LEU A 1 219 ? -15.785 -22.736 -18.214 1 65.232  ? 219 LEU A HD13 1 c 
ATOM   3356 H HD21 . LEU A 1 219 ? -17.722 -19.8   -17.382 1 55.483  ? 219 LEU A HD21 1 c 
ATOM   3357 H HD22 . LEU A 1 219 ? -16.552 -20.652 -16.733 1 55.482  ? 219 LEU A HD22 1 c 
ATOM   3358 H HD23 . LEU A 1 219 ? -17.927 -21.349 -17.106 1 55.577  ? 219 LEU A HD23 1 c 
ATOM   3359 N N    . SER A 1 220 ? -13.381 -17.927 -18.438 1 67.378  ? 220 SER A N    1 ? 
ATOM   3360 C CA   . SER A 1 220 ? -12.081 -17.297 -18.657 1 67.761  ? 220 SER A CA   1 ? 
ATOM   3361 C C    . SER A 1 220 ? -11.293 -17.985 -19.773 1 65.375  ? 220 SER A C    1 ? 
ATOM   3362 O O    . SER A 1 220 ? -10.381 -17.377 -20.32  1 70.253  ? 220 SER A O    1 ? 
ATOM   3363 C CB   . SER A 1 220 ? -11.264 -17.259 -17.391 1 72.118  ? 220 SER A CB   1 ? 
ATOM   3364 O OG   . SER A 1 220 ? -11.052 -18.583 -16.925 1 78.618  ? 220 SER A OG   1 ? 
ATOM   3365 H H    . SER A 1 220 ? -13.534 -18.342 -17.64  1 65.536  ? 220 SER A H    1 c 
ATOM   3366 H HA   . SER A 1 220 ? -12.247 -16.361 -18.939 1 68.029  ? 220 SER A HA   1 c 
ATOM   3367 H HB2  . SER A 1 220 ? -10.405 -16.831 -17.568 1 72.546  ? 220 SER A HB2  1 c 
ATOM   3368 H HB3  . SER A 1 220 ? -11.737 -16.743 -16.711 1 72.578  ? 220 SER A HB3  1 c 
ATOM   3369 N N    . SER A 1 221 ? -11.644 -19.236 -20.115 1 63.791  ? 221 SER A N    1 ? 
ATOM   3370 C CA   . SER A 1 221 ? -11.117 -19.899 -21.301 1 65.204  ? 221 SER A CA   1 ? 
ATOM   3371 C C    . SER A 1 221 ? -11.619 -19.27  -22.603 1 70.352  ? 221 SER A C    1 ? 
ATOM   3372 O O    . SER A 1 221 ? -11.116 -19.62  -23.665 1 66.385  ? 221 SER A O    1 ? 
ATOM   3373 C CB   . SER A 1 221 ? -11.451 -21.372 -21.285 1 68.636  ? 221 SER A CB   1 ? 
ATOM   3374 O OG   . SER A 1 221 ? -12.853 -21.598 -21.373 1 66.607  ? 221 SER A OG   1 ? 
ATOM   3375 H H    . SER A 1 221 ? -12.202 -19.709 -19.568 1 64.525  ? 221 SER A H    1 c 
ATOM   3376 H HA   . SER A 1 221 ? -10.13  -19.811 -21.283 1 66.479  ? 221 SER A HA   1 c 
ATOM   3377 H HB2  . SER A 1 221 ? -11.006 -21.81  -22.035 1 67.36   ? 221 SER A HB2  1 c 
ATOM   3378 H HB3  . SER A 1 221 ? -11.112 -21.769 -20.46  1 67.36   ? 221 SER A HB3  1 c 
ATOM   3379 N N    . GLY A 1 222 ? -12.646 -18.405 -22.533 1 72.206  ? 222 GLY A N    1 ? 
ATOM   3380 C CA   . GLY A 1 222 ? -13.335 -17.899 -23.708 1 66.626  ? 222 GLY A CA   1 ? 
ATOM   3381 C C    . GLY A 1 222 ? -14.47  -18.824 -24.142 1 67.92   ? 222 GLY A C    1 ? 
ATOM   3382 O O    . GLY A 1 222 ? -15.301 -18.423 -24.955 1 75.373  ? 222 GLY A O    1 ? 
ATOM   3383 H H    . GLY A 1 222 ? -12.943 -18.125 -21.718 1 70.268  ? 222 GLY A H    1 c 
ATOM   3384 H HA2  . GLY A 1 222 ? -13.701 -17.007 -23.503 1 68.21   ? 222 GLY A HA2  1 c 
ATOM   3385 H HA3  . GLY A 1 222 ? -12.691 -17.798 -24.448 1 68.206  ? 222 GLY A HA3  1 c 
ATOM   3386 N N    . GLU A 1 223 ? -14.52  -20.044 -23.578 1 69.406  ? 223 GLU A N    1 ? 
ATOM   3387 C CA   . GLU A 1 223 ? -15.606 -20.979 -23.836 1 68.135  ? 223 GLU A CA   1 ? 
ATOM   3388 C C    . GLU A 1 223 ? -16.926 -20.374 -23.335 1 68.367  ? 223 GLU A C    1 ? 
ATOM   3389 O O    . GLU A 1 223 ? -16.929 -19.48  -22.488 1 59.95   ? 223 GLU A O    1 ? 
ATOM   3390 C CB   . GLU A 1 223 ? -15.241 -22.331 -23.211 1 71.202  ? 223 GLU A CB   1 ? 
ATOM   3391 C CG   . GLU A 1 223 ? -16.108 -23.509 -23.651 1 79.883  ? 223 GLU A CG   1 ? 
ATOM   3392 H H    . GLU A 1 223 ? -13.859 -20.305 -23.007 1 68.828  ? 223 GLU A H    1 c 
ATOM   3393 H HA   . GLU A 1 223 ? -15.674 -21.099 -24.818 1 69.058  ? 223 GLU A HA   1 c 
ATOM   3394 H HB2  . GLU A 1 223 ? -14.31  -22.539 -23.435 1 72.32   ? 223 GLU A HB2  1 c 
ATOM   3395 H HB3  . GLU A 1 223 ? -15.301 -22.251 -22.236 1 72.334  ? 223 GLU A HB3  1 c 
ATOM   3396 N N    . GLU A 1 224 ? -18.044 -20.843 -23.906 1 70.431  ? 224 GLU A N    1 ? 
ATOM   3397 C CA   . GLU A 1 224 ? -19.37  -20.386 -23.534 1 68.03   ? 224 GLU A CA   1 ? 
ATOM   3398 C C    . GLU A 1 224 ? -19.809 -21.074 -22.248 1 68.279  ? 224 GLU A C    1 ? 
ATOM   3399 O O    . GLU A 1 224 ? -19.628 -22.29  -22.115 1 61.552  ? 224 GLU A O    1 ? 
ATOM   3400 C CB   . GLU A 1 224 ? -20.417 -20.782 -24.569 1 73.357  ? 224 GLU A CB   1 ? 
ATOM   3401 C CG   . GLU A 1 224 ? -20.136 -20.288 -25.983 1 81.325  ? 224 GLU A CG   1 ? 
ATOM   3402 C CD   . GLU A 1 224 ? -21.412 -20.29  -26.809 1 86.334  ? 224 GLU A CD   1 ? 
ATOM   3403 O OE1  . GLU A 1 224 ? -22.242 -21.214 -26.608 1 87.73   ? 224 GLU A OE1  1 ? 
ATOM   3404 O OE2  . GLU A 1 224 ? -21.586 -19.364 -27.629 1 81.656  ? 224 GLU A OE2  1 ? 
ATOM   3405 H H    . GLU A 1 224 ? -17.972 -21.468 -24.568 1 69.508  ? 224 GLU A H    1 c 
ATOM   3406 H HA   . GLU A 1 224 ? -19.358 -19.403 -23.41  1 69.34   ? 224 GLU A HA   1 c 
ATOM   3407 H HB2  . GLU A 1 224 ? -20.481 -21.76  -24.598 1 73.725  ? 224 GLU A HB2  1 c 
ATOM   3408 H HB3  . GLU A 1 224 ? -21.287 -20.436 -24.278 1 73.747  ? 224 GLU A HB3  1 c 
ATOM   3409 H HG2  . GLU A 1 224 ? -19.776 -19.376 -25.949 1 80.547  ? 224 GLU A HG2  1 c 
ATOM   3410 H HG3  . GLU A 1 224 ? -19.475 -20.872 -26.412 1 80.542  ? 224 GLU A HG3  1 c 
ATOM   3411 N N    . SER A 1 225 ? -20.446 -20.316 -21.34  1 57.577  ? 225 SER A N    1 ? 
ATOM   3412 C CA   . SER A 1 225 ? -20.955 -20.923 -20.118 1 54.144  ? 225 SER A CA   1 ? 
ATOM   3413 C C    . SER A 1 225 ? -22.382 -21.442 -20.333 1 50.963  ? 225 SER A C    1 ? 
ATOM   3414 O O    . SER A 1 225 ? -22.823 -21.602 -21.469 1 49.671  ? 225 SER A O    1 ? 
ATOM   3415 C CB   . SER A 1 225 ? -20.827 -19.996 -18.958 1 58.947  ? 225 SER A CB   1 ? 
ATOM   3416 O OG   . SER A 1 225 ? -20.941 -20.723 -17.741 1 66.566  ? 225 SER A OG   1 ? 
ATOM   3417 H H    . SER A 1 225 ? -20.565 -19.421 -21.48  1 59.284  ? 225 SER A H    1 c 
ATOM   3418 H HA   . SER A 1 225 ? -20.389 -21.706 -19.917 1 55.263  ? 225 SER A HA   1 c 
ATOM   3419 H HB2  . SER A 1 225 ? -19.96  -19.548 -18.993 1 59.482  ? 225 SER A HB2  1 c 
ATOM   3420 H HB3  . SER A 1 225 ? -21.528 -19.319 -19.002 1 59.388  ? 225 SER A HB3  1 c 
ATOM   3421 N N    . LEU A 1 226 ? -23.095 -21.739 -19.239 1 46.137  ? 226 LEU A N    1 ? 
ATOM   3422 C CA   . LEU A 1 226 ? -24.343 -22.481 -19.306 1 51.004  ? 226 LEU A CA   1 ? 
ATOM   3423 C C    . LEU A 1 226 ? -25.421 -21.694 -20.061 1 56.953  ? 226 LEU A C    1 ? 
ATOM   3424 O O    . LEU A 1 226 ? -25.506 -20.464 -19.961 1 56.534  ? 226 LEU A O    1 ? 
ATOM   3425 C CB   . LEU A 1 226 ? -24.799 -22.786 -17.877 1 51.399  ? 226 LEU A CB   1 ? 
ATOM   3426 C CG   . LEU A 1 226 ? -23.914 -23.719 -17.032 1 50.312  ? 226 LEU A CG   1 ? 
ATOM   3427 C CD1  . LEU A 1 226 ? -24.495 -23.886 -15.646 1 47.638  ? 226 LEU A CD1  1 ? 
ATOM   3428 C CD2  . LEU A 1 226 ? -23.729 -25.107 -17.611 1 48.576  ? 226 LEU A CD2  1 ? 
ATOM   3429 H H    . LEU A 1 226 ? -22.792 -21.47  -18.42  1 48.486  ? 226 LEU A H    1 c 
ATOM   3430 H HA   . LEU A 1 226 ? -24.169 -23.327 -19.782 1 51.099  ? 226 LEU A HA   1 c 
ATOM   3431 H HB2  . LEU A 1 226 ? -24.889 -21.931 -17.397 1 51.05   ? 226 LEU A HB2  1 c 
ATOM   3432 H HB3  . LEU A 1 226 ? -25.701 -23.18  -17.924 1 51.088  ? 226 LEU A HB3  1 c 
ATOM   3433 H HG   . LEU A 1 226 ? -23.019 -23.301 -16.942 1 49.66   ? 226 LEU A HG   1 c 
ATOM   3434 H HD11 . LEU A 1 226 ? -24.644 -23.012 -15.249 1 48.417  ? 226 LEU A HD11 1 c 
ATOM   3435 H HD12 . LEU A 1 226 ? -23.875 -24.39  -15.093 1 48.42   ? 226 LEU A HD12 1 c 
ATOM   3436 H HD13 . LEU A 1 226 ? -25.339 -24.364 -15.703 1 48.417  ? 226 LEU A HD13 1 c 
ATOM   3437 H HD21 . LEU A 1 226 ? -23.308 -25.044 -18.484 1 49.109  ? 226 LEU A HD21 1 c 
ATOM   3438 H HD22 . LEU A 1 226 ? -24.594 -25.539 -17.699 1 49.112  ? 226 LEU A HD22 1 c 
ATOM   3439 H HD23 . LEU A 1 226 ? -23.165 -25.633 -17.019 1 49.082  ? 226 LEU A HD23 1 c 
ATOM   3440 N N    . ASN A 1 227 ? -26.257 -22.437 -20.79  1 53.595  ? 227 ASN A N    1 ? 
ATOM   3441 C CA   . ASN A 1 227 ? -27.421 -21.919 -21.488 1 49.512  ? 227 ASN A CA   1 ? 
ATOM   3442 C C    . ASN A 1 227 ? -28.638 -22.608 -20.883 1 48.17   ? 227 ASN A C    1 ? 
ATOM   3443 O O    . ASN A 1 227 ? -28.464 -23.418 -19.975 1 50.387  ? 227 ASN A O    1 ? 
ATOM   3444 C CB   . ASN A 1 227 ? -27.283 -22.113 -22.992 1 48.935  ? 227 ASN A CB   1 ? 
ATOM   3445 C CG   . ASN A 1 227 ? -27.182 -23.565 -23.408 1 49.775  ? 227 ASN A CG   1 ? 
ATOM   3446 O OD1  . ASN A 1 227 ? -27.804 -24.462 -22.82  1 50.628  ? 227 ASN A OD1  1 ? 
ATOM   3447 N ND2  . ASN A 1 227 ? -26.43  -23.809 -24.468 1 49.668  ? 227 ASN A ND2  1 ? 
ATOM   3448 H H    . ASN A 1 227 ? -26.092 -23.333 -20.851 1 53.31   ? 227 ASN A H    1 c 
ATOM   3449 H HA   . ASN A 1 227 ? -27.495 -20.958 -21.32  1 49.985  ? 227 ASN A HA   1 c 
ATOM   3450 H HB2  . ASN A 1 227 ? -28.049 -21.71  -23.437 1 49.225  ? 227 ASN A HB2  1 c 
ATOM   3451 H HB3  . ASN A 1 227 ? -26.482 -21.642 -23.297 1 49.254  ? 227 ASN A HB3  1 c 
ATOM   3452 H HD21 . ASN A 1 227 ? -25.888 -24.511 -24.473 1 49.7    ? 227 ASN A HD21 1 c 
ATOM   3453 H HD22 . ASN A 1 227 ? -26.467 -23.269 -25.171 1 49.696  ? 227 ASN A HD22 1 c 
ATOM   3454 N N    . VAL A 1 228 ? -29.839 -22.32  -21.413 1 43.636  ? 228 VAL A N    1 ? 
ATOM   3455 C CA   . VAL A 1 228 ? -31.088 -22.715 -20.777 1 41.613  ? 228 VAL A CA   1 ? 
ATOM   3456 C C    . VAL A 1 228 ? -31.259 -24.22  -20.917 1 43.191  ? 228 VAL A C    1 ? 
ATOM   3457 O O    . VAL A 1 228 ? -31.799 -24.851 -20.008 1 49.094  ? 228 VAL A O    1 ? 
ATOM   3458 C CB   . VAL A 1 228 ? -32.311 -21.941 -21.333 1 46.235  ? 228 VAL A CB   1 ? 
ATOM   3459 C CG1  . VAL A 1 228 ? -33.66  -22.565 -20.97  1 49.757  ? 228 VAL A CG1  1 ? 
ATOM   3460 C CG2  . VAL A 1 228 ? -32.291 -20.468 -20.929 1 49.222  ? 228 VAL A CG2  1 ? 
ATOM   3461 H H    . VAL A 1 228 ? -29.882 -21.849 -22.194 1 44.355  ? 228 VAL A H    1 c 
ATOM   3462 H HA   . VAL A 1 228 ? -31.014 -22.51  -19.824 1 43.166  ? 228 VAL A HA   1 c 
ATOM   3463 H HB   . VAL A 1 228 ? -32.246 -21.973 -22.313 1 46.497  ? 228 VAL A HB   1 c 
ATOM   3464 H HG11 . VAL A 1 228 ? -33.635 -22.885 -20.053 1 48.661  ? 228 VAL A HG11 1 c 
ATOM   3465 H HG12 . VAL A 1 228 ? -33.847 -23.309 -21.568 1 48.661  ? 228 VAL A HG12 1 c 
ATOM   3466 H HG13 . VAL A 1 228 ? -34.362 -21.899 -21.059 1 48.683  ? 228 VAL A HG13 1 c 
ATOM   3467 H HG21 . VAL A 1 228 ? -32.972 -19.985 -21.427 1 48.324  ? 228 VAL A HG21 1 c 
ATOM   3468 H HG22 . VAL A 1 228 ? -31.417 -20.09  -21.125 1 48.303  ? 228 VAL A HG22 1 c 
ATOM   3469 H HG23 . VAL A 1 228 ? -32.47  -20.39  -19.977 1 48.334  ? 228 VAL A HG23 1 c 
ATOM   3470 N N    . GLU A 1 229 ? -30.865 -24.766 -22.075 1 48.302  ? 229 GLU A N    1 ? 
ATOM   3471 C CA   . GLU A 1 229 ? -30.864 -26.212 -22.28  1 53.71   ? 229 GLU A CA   1 ? 
ATOM   3472 C C    . GLU A 1 229 ? -29.962 -26.882 -21.236 1 51.317  ? 229 GLU A C    1 ? 
ATOM   3473 O O    . GLU A 1 229 ? -30.375 -27.849 -20.59  1 44.353  ? 229 GLU A O    1 ? 
ATOM   3474 C CB   . GLU A 1 229 ? -30.448 -26.609 -23.701 1 58.618  ? 229 GLU A CB   1 ? 
ATOM   3475 C CG   . GLU A 1 229 ? -31.387 -26.107 -24.798 1 62.094  ? 229 GLU A CG   1 ? 
ATOM   3476 C CD   . GLU A 1 229 ? -31.195 -24.693 -25.344 1 67.749  ? 229 GLU A CD   1 ? 
ATOM   3477 O OE1  . GLU A 1 229 ? -32.029 -24.306 -26.194 1 74.69   ? 229 GLU A OE1  1 ? 
ATOM   3478 O OE2  . GLU A 1 229 ? -30.237 -23.981 -24.962 1 61.354  ? 229 GLU A OE2  1 ? 
ATOM   3479 H H    . GLU A 1 229 ? -30.588 -24.226 -22.757 1 48.306  ? 229 GLU A H    1 c 
ATOM   3480 H HA   . GLU A 1 229 ? -31.789 -26.537 -22.138 1 52.999  ? 229 GLU A HA   1 c 
ATOM   3481 H HB2  . GLU A 1 229 ? -29.545 -26.27  -23.87  1 58.237  ? 229 GLU A HB2  1 c 
ATOM   3482 H HB3  . GLU A 1 229 ? -30.41  -27.587 -23.752 1 58.228  ? 229 GLU A HB3  1 c 
ATOM   3483 H HG2  . GLU A 1 229 ? -31.326 -26.727 -25.556 1 62.528  ? 229 GLU A HG2  1 c 
ATOM   3484 H HG3  . GLU A 1 229 ? -32.304 -26.173 -24.464 1 62.545  ? 229 GLU A HG3  1 c 
ATOM   3485 N N    . ASP A 1 230 ? -28.75  -26.345 -21.032 1 49.946  ? 230 ASP A N    1 ? 
ATOM   3486 C CA   . ASP A 1 230 ? -27.844 -26.892 -20.025 1 54.89   ? 230 ASP A CA   1 ? 
ATOM   3487 C C    . ASP A 1 230 ? -28.521 -26.931 -18.659 1 58.576  ? 230 ASP A C    1 ? 
ATOM   3488 O O    . ASP A 1 230 ? -28.509 -27.974 -18.001 1 56.156  ? 230 ASP A O    1 ? 
ATOM   3489 C CB   . ASP A 1 230 ? -26.53  -26.14  -19.906 1 51.302  ? 230 ASP A CB   1 ? 
ATOM   3490 C CG   . ASP A 1 230 ? -25.642 -26.158 -21.14  1 54.157  ? 230 ASP A CG   1 ? 
ATOM   3491 O OD1  . ASP A 1 230 ? -25.583 -27.22  -21.799 1 56.505  ? 230 ASP A OD1  1 ? 
ATOM   3492 O OD2  . ASP A 1 230 ? -24.969 -25.132 -21.398 1 50.735  ? 230 ASP A OD2  1 ? 
ATOM   3493 H H    . ASP A 1 230 ? -28.476 -25.631 -21.533 1 51.353  ? 230 ASP A H    1 c 
ATOM   3494 H HA   . ASP A 1 230 ? -27.63  -27.817 -20.283 1 53.887  ? 230 ASP A HA   1 c 
ATOM   3495 H HB2  . ASP A 1 230 ? -26.706 -25.212 -19.655 1 52.727  ? 230 ASP A HB2  1 c 
ATOM   3496 H HB3  . ASP A 1 230 ? -26.019 -26.551 -19.179 1 52.76   ? 230 ASP A HB3  1 c 
ATOM   3497 N N    . PHE A 1 231 ? -29.146 -25.806 -18.268 1 53.888  ? 231 PHE A N    1 ? 
ATOM   3498 C CA   . PHE A 1 231 ? -29.89  -25.739 -17.018 1 48.627  ? 231 PHE A CA   1 ? 
ATOM   3499 C C    . PHE A 1 231 ? -31.038 -26.739 -17.049 1 43.186  ? 231 PHE A C    1 ? 
ATOM   3500 O O    . PHE A 1 231 ? -31.405 -27.285 -16.015 1 50.013  ? 231 PHE A O    1 ? 
ATOM   3501 C CB   . PHE A 1 231 ? -30.429 -24.342 -16.665 1 51.426  ? 231 PHE A CB   1 ? 
ATOM   3502 C CG   . PHE A 1 231 ? -29.398 -23.401 -16.052 1 47.04   ? 231 PHE A CG   1 ? 
ATOM   3503 C CD1  . PHE A 1 231 ? -29.025 -23.522 -14.716 1 46.453  ? 231 PHE A CD1  1 ? 
ATOM   3504 C CD2  . PHE A 1 231 ? -28.792 -22.409 -16.814 1 43.94   ? 231 PHE A CD2  1 ? 
ATOM   3505 C CE1  . PHE A 1 231 ? -28.087 -22.655 -14.157 1 41.593  ? 231 PHE A CE1  1 ? 
ATOM   3506 C CE2  . PHE A 1 231 ? -27.842 -21.555 -16.253 1 45.317  ? 231 PHE A CE2  1 ? 
ATOM   3507 C CZ   . PHE A 1 231 ? -27.497 -21.682 -14.926 1 42.224  ? 231 PHE A CZ   1 ? 
ATOM   3508 H H    . PHE A 1 231 ? -29.098 -25.058 -18.79  1 53.695  ? 231 PHE A H    1 c 
ATOM   3509 H HA   . PHE A 1 231 ? -29.272 -26.013 -16.29  1 49.097  ? 231 PHE A HA   1 c 
ATOM   3510 H HB2  . PHE A 1 231 ? -30.782 -23.932 -17.485 1 49.685  ? 231 PHE A HB2  1 c 
ATOM   3511 H HB3  . PHE A 1 231 ? -31.178 -24.441 -16.039 1 49.719  ? 231 PHE A HB3  1 c 
ATOM   3512 H HD1  . PHE A 1 231 ? -29.427 -24.186 -14.18  1 45.396  ? 231 PHE A HD1  1 c 
ATOM   3513 H HD2  . PHE A 1 231 ? -29.027 -22.313 -17.722 1 45.031  ? 231 PHE A HD2  1 c 
ATOM   3514 H HE1  . PHE A 1 231 ? -27.845 -22.749 -13.25  1 42.888  ? 231 PHE A HE1  1 c 
ATOM   3515 H HE2  . PHE A 1 231 ? -27.445 -20.882 -16.782 1 44.274  ? 231 PHE A HE2  1 c 
ATOM   3516 H HZ   . PHE A 1 231 ? -26.857 -21.102 -14.545 1 42.84   ? 231 PHE A HZ   1 c 
ATOM   3517 N N    . GLU A 1 232 ? -31.672 -26.92  -18.2   1 44.218  ? 232 GLU A N    1 ? 
ATOM   3518 C CA   . GLU A 1 232 ? -32.751 -27.895 -18.279 1 54.162  ? 232 GLU A CA   1 ? 
ATOM   3519 C C    . GLU A 1 232 ? -32.188 -29.304 -18.02  1 57.298  ? 232 GLU A C    1 ? 
ATOM   3520 O O    . GLU A 1 232 ? -32.786 -30.08  -17.265 1 45.91   ? 232 GLU A O    1 ? 
ATOM   3521 C CB   . GLU A 1 232 ? -33.499 -27.773 -19.606 1 54.558  ? 232 GLU A CB   1 ? 
ATOM   3522 C CG   . GLU A 1 232 ? -34.756 -28.64  -19.665 1 62.532  ? 232 GLU A CG   1 ? 
ATOM   3523 C CD   . GLU A 1 232 ? -35.432 -28.665 -21.03  1 68.533  ? 232 GLU A CD   1 ? 
ATOM   3524 O OE1  . GLU A 1 232 ? -36.676 -28.74  -21.09  1 67.557  ? 232 GLU A OE1  1 ? 
ATOM   3525 O OE2  . GLU A 1 232 ? -34.711 -28.598 -22.047 1 71.316  ? 232 GLU A OE2  1 ? 
ATOM   3526 H H    . GLU A 1 232 ? -31.465 -26.417 -18.934 1 46.166  ? 232 GLU A H    1 c 
ATOM   3527 H HA   . GLU A 1 232 ? -33.402 -27.689 -17.561 1 52.591  ? 232 GLU A HA   1 c 
ATOM   3528 H HB2  . GLU A 1 232 ? -33.735 -26.835 -19.755 1 56.078  ? 232 GLU A HB2  1 c 
ATOM   3529 H HB3  . GLU A 1 232 ? -32.899 -28.046 -20.328 1 56.168  ? 232 GLU A HB3  1 c 
ATOM   3530 H HG2  . GLU A 1 232 ? -34.524 -29.561 -19.421 1 61.871  ? 232 GLU A HG2  1 c 
ATOM   3531 H HG3  . GLU A 1 232 ? -35.4   -28.315 -19.004 1 61.782  ? 232 GLU A HG3  1 c 
ATOM   3532 N N    . ASN A 1 233 ? -30.995 -29.606 -18.574 1 56.727  ? 233 ASN A N    1 ? 
ATOM   3533 C CA   . ASN A 1 233 ? -30.407 -30.946 -18.498 1 55.442  ? 233 ASN A CA   1 ? 
ATOM   3534 C C    . ASN A 1 233 ? -30.113 -31.389 -17.063 1 56.835  ? 233 ASN A C    1 ? 
ATOM   3535 O O    . ASN A 1 233 ? -30.099 -32.591 -16.788 1 57.788  ? 233 ASN A O    1 ? 
ATOM   3536 C CB   . ASN A 1 233 ? -29.164 -31.049 -19.37  1 48.914  ? 233 ASN A CB   1 ? 
ATOM   3537 C CG   . ASN A 1 233 ? -29.523 -31.065 -20.833 1 47.757  ? 233 ASN A CG   1 ? 
ATOM   3538 O OD1  . ASN A 1 233 ? -30.676 -31.336 -21.175 1 44.981  ? 233 ASN A OD1  1 ? 
ATOM   3539 N ND2  . ASN A 1 233 ? -28.56  -30.794 -21.704 1 49.708  ? 233 ASN A ND2  1 ? 
ATOM   3540 H H    . ASN A 1 233 ? -30.541 -28.959 -19.031 1 56.362  ? 233 ASN A H    1 c 
ATOM   3541 H HA   . ASN A 1 233 ? -31.069 -31.578 -18.857 1 54.551  ? 233 ASN A HA   1 c 
ATOM   3542 H HB2  . ASN A 1 233 ? -28.575 -30.291 -19.19  1 50.124  ? 233 ASN A HB2  1 c 
ATOM   3543 H HB3  . ASN A 1 233 ? -28.68  -31.87  -19.149 1 50.097  ? 233 ASN A HB3  1 c 
ATOM   3544 H HD21 . ASN A 1 233 ? -28.761 -30.425 -22.485 1 49.099  ? 233 ASN A HD21 1 c 
ATOM   3545 H HD22 . ASN A 1 233 ? -27.716 -30.982 -21.504 1 49.098  ? 233 ASN A HD22 1 c 
ATOM   3546 N N    . TRP A 1 234 ? -29.927 -30.418 -16.155 1 48.776  ? 234 TRP A N    1 ? 
ATOM   3547 C CA   . TRP A 1 234 ? -29.638 -30.686 -14.762 1 46.82   ? 234 TRP A CA   1 ? 
ATOM   3548 C C    . TRP A 1 234 ? -30.812 -30.366 -13.833 1 49.564  ? 234 TRP A C    1 ? 
ATOM   3549 O O    . TRP A 1 234 ? -30.602 -30.273 -12.621 1 54.367  ? 234 TRP A O    1 ? 
ATOM   3550 C CB   . TRP A 1 234 ? -28.378 -29.887 -14.411 1 53.609  ? 234 TRP A CB   1 ? 
ATOM   3551 C CG   . TRP A 1 234 ? -27.149 -30.394 -15.114 1 55.392  ? 234 TRP A CG   1 ? 
ATOM   3552 C CD1  . TRP A 1 234 ? -26.627 -30.017 -16.314 1 59.61   ? 234 TRP A CD1  1 ? 
ATOM   3553 C CD2  . TRP A 1 234 ? -26.281 -31.427 -14.61  1 60.241  ? 234 TRP A CD2  1 ? 
ATOM   3554 N NE1  . TRP A 1 234 ? -25.49  -30.732 -16.587 1 62.881  ? 234 TRP A NE1  1 ? 
ATOM   3555 C CE2  . TRP A 1 234 ? -25.254 -31.605 -15.561 1 56.696  ? 234 TRP A CE2  1 ? 
ATOM   3556 C CE3  . TRP A 1 234 ? -26.275 -32.206 -13.446 1 64.77   ? 234 TRP A CE3  1 ? 
ATOM   3557 C CZ2  . TRP A 1 234 ? -24.231 -32.531 -15.381 1 56.278  ? 234 TRP A CZ2  1 ? 
ATOM   3558 C CZ3  . TRP A 1 234 ? -25.256 -33.119 -13.269 1 65.854  ? 234 TRP A CZ3  1 ? 
ATOM   3559 C CH2  . TRP A 1 234 ? -24.253 -33.279 -14.229 1 55.804  ? 234 TRP A CH2  1 ? 
ATOM   3560 H H    . TRP A 1 234 ? -29.952 -29.546 -16.424 1 50.267  ? 234 TRP A H    1 c 
ATOM   3561 H HA   . TRP A 1 234 ? -29.42  -31.652 -14.663 1 49.009  ? 234 TRP A HA   1 c 
ATOM   3562 H HB2  . TRP A 1 234 ? -28.522 -28.948 -14.656 1 52.372  ? 234 TRP A HB2  1 c 
ATOM   3563 H HB3  . TRP A 1 234 ? -28.231 -29.935 -13.443 1 52.383  ? 234 TRP A HB3  1 c 
ATOM   3564 H HD1  . TRP A 1 234 ? -26.978 -29.355 -16.875 1 59.29   ? 234 TRP A HD1  1 c 
ATOM   3565 H HE1  . TRP A 1 234 ? -24.998 -30.645 -17.303 1 60.541  ? 234 TRP A HE1  1 c 
ATOM   3566 H HE3  . TRP A 1 234 ? -26.947 -32.1   -12.794 1 63.774  ? 234 TRP A HE3  1 c 
ATOM   3567 H HZ2  . TRP A 1 234 ? -23.552 -32.64  -16.024 1 56.415  ? 234 TRP A HZ2  1 c 
ATOM   3568 H HZ3  . TRP A 1 234 ? -25.239 -33.649 -12.491 1 63.004  ? 234 TRP A HZ3  1 c 
ATOM   3569 H HH2  . TRP A 1 234 ? -23.574 -33.913 -14.082 1 58.161  ? 234 TRP A HH2  1 c 
ATOM   3570 N N    . GLY A 1 235 ? -32.028 -30.186 -14.388 1 50.406  ? 235 GLY A N    1 ? 
ATOM   3571 C CA   . GLY A 1 235 ? -33.26  -30.03  -13.614 1 51.82   ? 235 GLY A CA   1 ? 
ATOM   3572 C C    . GLY A 1 235 ? -33.548 -28.615 -13.068 1 54.679  ? 235 GLY A C    1 ? 
ATOM   3573 O O    . GLY A 1 235 ? -34.212 -28.484 -12.041 1 49.465  ? 235 GLY A O    1 ? 
ATOM   3574 H H    . GLY A 1 235 ? -32.095 -30.163 -15.298 1 50.544  ? 235 GLY A H    1 c 
ATOM   3575 H HA2  . GLY A 1 235 ? -34.015 -30.304 -14.185 1 52.095  ? 235 GLY A HA2  1 c 
ATOM   3576 H HA3  . GLY A 1 235 ? -33.229 -30.659 -12.855 1 52.093  ? 235 GLY A HA3  1 c 
ATOM   3577 N N    . PHE A 1 236 ? -33.081 -27.549 -13.736 1 53.798  ? 236 PHE A N    1 ? 
ATOM   3578 C CA   . PHE A 1 236 ? -33.307 -26.186 -13.265 1 52.716  ? 236 PHE A CA   1 ? 
ATOM   3579 C C    . PHE A 1 236 ? -34.347 -25.503 -14.157 1 47.74   ? 236 PHE A C    1 ? 
ATOM   3580 O O    . PHE A 1 236 ? -34.199 -25.456 -15.38  1 49.531  ? 236 PHE A O    1 ? 
ATOM   3581 C CB   . PHE A 1 236 ? -32.003 -25.377 -13.215 1 51.148  ? 236 PHE A CB   1 ? 
ATOM   3582 C CG   . PHE A 1 236 ? -31.047 -25.88  -12.142 1 53.187  ? 236 PHE A CG   1 ? 
ATOM   3583 C CD1  . PHE A 1 236 ? -30.153 -26.916 -12.419 1 48.407  ? 236 PHE A CD1  1 ? 
ATOM   3584 C CD2  . PHE A 1 236 ? -31.074 -25.357 -10.851 1 51.374  ? 236 PHE A CD2  1 ? 
ATOM   3585 C CE1  . PHE A 1 236 ? -29.311 -27.413 -11.428 1 51.897  ? 236 PHE A CE1  1 ? 
ATOM   3586 C CE2  . PHE A 1 236 ? -30.211 -25.84  -9.869  1 54.615  ? 236 PHE A CE2  1 ? 
ATOM   3587 C CZ   . PHE A 1 236 ? -29.336 -26.877 -10.159 1 52.743  ? 236 PHE A CZ   1 ? 
ATOM   3588 H H    . PHE A 1 236 ? -32.613 -27.673 -14.512 1 53.738  ? 236 PHE A H    1 c 
ATOM   3589 H HA   . PHE A 1 236 ? -33.666 -26.228 -12.341 1 51.632  ? 236 PHE A HA   1 c 
ATOM   3590 H HB2  . PHE A 1 236 ? -31.562 -25.437 -14.089 1 51.928  ? 236 PHE A HB2  1 c 
ATOM   3591 H HB3  . PHE A 1 236 ? -32.22  -24.435 -13.039 1 51.93   ? 236 PHE A HB3  1 c 
ATOM   3592 H HD1  . PHE A 1 236 ? -30.139 -27.301 -13.281 1 50.333  ? 236 PHE A HD1  1 c 
ATOM   3593 H HD2  . PHE A 1 236 ? -31.669 -24.654 -10.646 1 52.483  ? 236 PHE A HD2  1 c 
ATOM   3594 H HE1  . PHE A 1 236 ? -28.706 -28.107 -11.632 1 51.296  ? 236 PHE A HE1  1 c 
ATOM   3595 H HE2  . PHE A 1 236 ? -30.231 -25.468 -9.006  1 53.366  ? 236 PHE A HE2  1 c 
ATOM   3596 H HZ   . PHE A 1 236 ? -28.748 -27.198 -9.499  1 52.804  ? 236 PHE A HZ   1 c 
ATOM   3597 N N    . SER A 1 237 ? -35.402 -24.991 -13.522 1 47.594  ? 237 SER A N    1 ? 
ATOM   3598 C CA   . SER A 1 237 ? -36.351 -24.065 -14.139 1 47.494  ? 237 SER A CA   1 ? 
ATOM   3599 C C    . SER A 1 237 ? -35.713 -22.687 -14.277 1 44.262  ? 237 SER A C    1 ? 
ATOM   3600 O O    . SER A 1 237 ? -35.019 -22.288 -13.357 1 47.111  ? 237 SER A O    1 ? 
ATOM   3601 C CB   . SER A 1 237 ? -37.593 -23.959 -13.297 1 46.551  ? 237 SER A CB   1 ? 
ATOM   3602 O OG   . SER A 1 237 ? -38.351 -25.157 -13.359 1 58.078  ? 237 SER A OG   1 ? 
ATOM   3603 H H    . SER A 1 237 ? -35.548 -25.236 -12.654 1 47.68   ? 237 SER A H    1 c 
ATOM   3604 H HA   . SER A 1 237 ? -36.593 -24.405 -15.033 1 46.726  ? 237 SER A HA   1 c 
ATOM   3605 H HB2  . SER A 1 237 ? -37.343 -23.777 -12.371 1 49.3    ? 237 SER A HB2  1 c 
ATOM   3606 H HB3  . SER A 1 237 ? -38.134 -23.216 -13.617 1 49.364  ? 237 SER A HB3  1 c 
ATOM   3607 N N    . VAL A 1 238 ? -35.977 -21.969 -15.384 1 44.257  ? 238 VAL A N    1 ? 
ATOM   3608 C CA   . VAL A 1 238 ? -35.439 -20.632 -15.585 1 44.537  ? 238 VAL A CA   1 ? 
ATOM   3609 C C    . VAL A 1 238 ? -36.539 -19.589 -15.845 1 49.169  ? 238 VAL A C    1 ? 
ATOM   3610 O O    . VAL A 1 238 ? -37.67  -19.912 -16.211 1 49.837  ? 238 VAL A O    1 ? 
ATOM   3611 C CB   . VAL A 1 238 ? -34.396 -20.61  -16.712 1 47.871  ? 238 VAL A CB   1 ? 
ATOM   3612 C CG1  . VAL A 1 238 ? -33.308 -21.668 -16.507 1 47.954  ? 238 VAL A CG1  1 ? 
ATOM   3613 C CG2  . VAL A 1 238 ? -35.041 -20.747 -18.086 1 51.941  ? 238 VAL A CG2  1 ? 
ATOM   3614 H H    . VAL A 1 238 ? -36.515 -22.326 -16.03  1 44.406  ? 238 VAL A H    1 c 
ATOM   3615 H HA   . VAL A 1 238 ? -34.984 -20.375 -14.767 1 45.904  ? 238 VAL A HA   1 c 
ATOM   3616 H HB   . VAL A 1 238 ? -33.957 -19.727 -16.68  1 47.974  ? 238 VAL A HB   1 c 
ATOM   3617 H HG11 . VAL A 1 238 ? -33.566 -22.491 -16.955 1 47.927  ? 238 VAL A HG11 1 c 
ATOM   3618 H HG12 . VAL A 1 238 ? -33.196 -21.84  -15.557 1 47.871  ? 238 VAL A HG12 1 c 
ATOM   3619 H HG13 . VAL A 1 238 ? -32.469 -21.348 -16.879 1 47.918  ? 238 VAL A HG13 1 c 
ATOM   3620 H HG21 . VAL A 1 238 ? -34.387 -21.084 -18.718 1 50.624  ? 238 VAL A HG21 1 c 
ATOM   3621 H HG22 . VAL A 1 238 ? -35.358 -19.878 -18.387 1 50.658  ? 238 VAL A HG22 1 c 
ATOM   3622 H HG23 . VAL A 1 238 ? -35.79  -21.364 -18.037 1 50.568  ? 238 VAL A HG23 1 c 
ATOM   3623 N N    . TYR A 1 239 ? -36.158 -18.319 -15.629 1 47.553  ? 239 TYR A N    1 ? 
ATOM   3624 C CA   . TYR A 1 239 ? -36.959 -17.133 -15.902 1 45.663  ? 239 TYR A CA   1 ? 
ATOM   3625 C C    . TYR A 1 239 ? -36.126 -16.199 -16.772 1 42.995  ? 239 TYR A C    1 ? 
ATOM   3626 O O    . TYR A 1 239 ? -34.935 -16.02  -16.515 1 43.481  ? 239 TYR A O    1 ? 
ATOM   3627 C CB   . TYR A 1 239 ? -37.33  -16.318 -14.657 1 47.073  ? 239 TYR A CB   1 ? 
ATOM   3628 C CG   . TYR A 1 239 ? -38.322 -17.001 -13.728 1 41.168  ? 239 TYR A CG   1 ? 
ATOM   3629 C CD1  . TYR A 1 239 ? -37.927 -18     -12.845 1 44.198  ? 239 TYR A CD1  1 ? 
ATOM   3630 C CD2  . TYR A 1 239 ? -39.657 -16.641 -13.727 1 41.607  ? 239 TYR A CD2  1 ? 
ATOM   3631 C CE1  . TYR A 1 239 ? -38.84  -18.654 -12.029 1 43.203  ? 239 TYR A CE1  1 ? 
ATOM   3632 C CE2  . TYR A 1 239 ? -40.587 -17.277 -12.907 1 46.745  ? 239 TYR A CE2  1 ? 
ATOM   3633 C CZ   . TYR A 1 239 ? -40.179 -18.291 -12.061 1 45.338  ? 239 TYR A CZ   1 ? 
ATOM   3634 O OH   . TYR A 1 239 ? -41.113 -18.878 -11.267 1 47.268  ? 239 TYR A OH   1 ? 
ATOM   3635 H H    . TYR A 1 239 ? -35.324 -18.186 -15.281 1 47.427  ? 239 TYR A H    1 c 
ATOM   3636 H HA   . TYR A 1 239 ? -37.786 -17.392 -16.386 1 45.774  ? 239 TYR A HA   1 c 
ATOM   3637 H HB2  . TYR A 1 239 ? -36.507 -16.124 -14.155 1 45.312  ? 239 TYR A HB2  1 c 
ATOM   3638 H HB3  . TYR A 1 239 ? -37.713 -15.462 -14.95  1 45.258  ? 239 TYR A HB3  1 c 
ATOM   3639 H HD1  . TYR A 1 239 ? -37.023 -18.273 -12.834 1 43.295  ? 239 TYR A HD1  1 c 
ATOM   3640 H HD2  . TYR A 1 239 ? -39.953 -15.968 -14.319 1 42.734  ? 239 TYR A HD2  1 c 
ATOM   3641 H HE1  . TYR A 1 239 ? -38.551 -19.335 -11.446 1 43.934  ? 239 TYR A HE1  1 c 
ATOM   3642 H HE2  . TYR A 1 239 ? -41.493 -17.023 -12.935 1 45.147  ? 239 TYR A HE2  1 c 
ATOM   3643 N N    . ASN A 1 240 ? -36.77  -15.595 -17.788 1 44.871  ? 240 ASN A N    1 ? 
ATOM   3644 C CA   . ASN A 1 240 ? -36.103 -14.714 -18.739 1 40.948  ? 240 ASN A CA   1 ? 
ATOM   3645 C C    . ASN A 1 240 ? -36.008 -13.289 -18.178 1 41.699  ? 240 ASN A C    1 ? 
ATOM   3646 O O    . ASN A 1 240 ? -37.019 -12.629 -18.007 1 37.626  ? 240 ASN A O    1 ? 
ATOM   3647 C CB   . ASN A 1 240 ? -36.845 -14.732 -20.063 1 39.951  ? 240 ASN A CB   1 ? 
ATOM   3648 C CG   . ASN A 1 240 ? -36.159 -13.95  -21.154 1 44.296  ? 240 ASN A CG   1 ? 
ATOM   3649 O OD1  . ASN A 1 240 ? -34.997 -13.54  -21.033 1 46.667  ? 240 ASN A OD1  1 ? 
ATOM   3650 N ND2  . ASN A 1 240 ? -36.874 -13.77  -22.251 1 47.796  ? 240 ASN A ND2  1 ? 
ATOM   3651 H H    . ASN A 1 240 ? -37.668 -15.735 -17.886 1 43.517  ? 240 ASN A H    1 c 
ATOM   3652 H HA   . ASN A 1 240 ? -35.198 -15.06  -18.903 1 41.679  ? 240 ASN A HA   1 c 
ATOM   3653 H HB2  . ASN A 1 240 ? -36.948 -15.658 -20.356 1 41.149  ? 240 ASN A HB2  1 c 
ATOM   3654 H HB3  . ASN A 1 240 ? -37.741 -14.363 -19.928 1 41.127  ? 240 ASN A HB3  1 c 
ATOM   3655 H HD21 . ASN A 1 240 ? -36.876 -12.98  -22.653 1 46.679  ? 240 ASN A HD21 1 c 
ATOM   3656 H HD22 . ASN A 1 240 ? -37.35  -14.441 -22.584 1 46.641  ? 240 ASN A HD22 1 c 
ATOM   3657 N N    . TYR A 1 241 ? -34.786 -12.839 -17.883 1 42.344  ? 241 TYR A N    1 ? 
ATOM   3658 C CA   . TYR A 1 241 ? -34.482 -11.487 -17.442 1 42.712  ? 241 TYR A CA   1 ? 
ATOM   3659 C C    . TYR A 1 241 ? -33.524 -10.874 -18.459 1 43.01   ? 241 TYR A C    1 ? 
ATOM   3660 O O    . TYR A 1 241 ? -32.569 -10.183 -18.104 1 41.656  ? 241 TYR A O    1 ? 
ATOM   3661 C CB   . TYR A 1 241 ? -33.883 -11.535 -16.03  1 43.003  ? 241 TYR A CB   1 ? 
ATOM   3662 C CG   . TYR A 1 241 ? -34.859 -11.682 -14.873 1 38.941  ? 241 TYR A CG   1 ? 
ATOM   3663 C CD1  . TYR A 1 241 ? -35.685 -12.791 -14.753 1 41.813  ? 241 TYR A CD1  1 ? 
ATOM   3664 C CD2  . TYR A 1 241 ? -34.949 -10.7   -13.898 1 37.694  ? 241 TYR A CD2  1 ? 
ATOM   3665 C CE1  . TYR A 1 241 ? -36.571 -12.924 -13.698 1 42.021  ? 241 TYR A CE1  1 ? 
ATOM   3666 C CE2  . TYR A 1 241 ? -35.838 -10.818 -12.841 1 38.524  ? 241 TYR A CE2  1 ? 
ATOM   3667 C CZ   . TYR A 1 241 ? -36.645 -11.935 -12.734 1 41.72   ? 241 TYR A CZ   1 ? 
ATOM   3668 O OH   . TYR A 1 241 ? -37.528 -12.05  -11.704 1 43.005  ? 241 TYR A OH   1 ? 
ATOM   3669 H H    . TYR A 1 241 ? -34.086 -13.423 -17.957 1 42.259  ? 241 TYR A H    1 c 
ATOM   3670 H HA   . TYR A 1 241 ? -35.318 -10.95  -17.421 1 42.705  ? 241 TYR A HA   1 c 
ATOM   3671 H HB2  . TYR A 1 241 ? -33.249 -12.285 -15.996 1 41.963  ? 241 TYR A HB2  1 c 
ATOM   3672 H HB3  . TYR A 1 241 ? -33.362 -10.715 -15.887 1 41.921  ? 241 TYR A HB3  1 c 
ATOM   3673 H HD1  . TYR A 1 241 ? -35.637 -13.476 -15.4   1 41.172  ? 241 TYR A HD1  1 c 
ATOM   3674 H HD2  . TYR A 1 241 ? -34.402 -9.934  -13.958 1 38.298  ? 241 TYR A HD2  1 c 
ATOM   3675 H HE1  . TYR A 1 241 ? -37.123 -13.682 -13.634 1 41.903  ? 241 TYR A HE1  1 c 
ATOM   3676 H HE2  . TYR A 1 241 ? -35.885 -10.142 -12.189 1 39.142  ? 241 TYR A HE2  1 c 
ATOM   3677 N N    . ASN A 1 242 ? -33.784 -11.167 -19.735 1 42.014  ? 242 ASN A N    1 ? 
ATOM   3678 C CA   . ASN A 1 242 ? -32.998 -10.662 -20.852 1 46.016  ? 242 ASN A CA   1 ? 
ATOM   3679 C C    . ASN A 1 242 ? -32.393 -9.276  -20.597 1 48.374  ? 242 ASN A C    1 ? 
ATOM   3680 O O    . ASN A 1 242 ? -33.11  -8.276  -20.516 1 43.834  ? 242 ASN A O    1 ? 
ATOM   3681 C CB   . ASN A 1 242 ? -33.893 -10.599 -22.082 1 45.866  ? 242 ASN A CB   1 ? 
ATOM   3682 C CG   . ASN A 1 242 ? -33.098 -10.519 -23.352 1 46.84   ? 242 ASN A CG   1 ? 
ATOM   3683 O OD1  . ASN A 1 242 ? -32.313 -9.575  -23.519 1 47.86   ? 242 ASN A OD1  1 ? 
ATOM   3684 N ND2  . ASN A 1 242 ? -33.273 -11.505 -24.224 1 47.801  ? 242 ASN A ND2  1 ? 
ATOM   3685 H H    . ASN A 1 242 ? -34.502 -11.698 -19.925 1 43.157  ? 242 ASN A H    1 c 
ATOM   3686 H HA   . ASN A 1 242 ? -32.276 -11.303 -21.037 1 45.61   ? 242 ASN A HA   1 c 
ATOM   3687 H HB2  . ASN A 1 242 ? -34.463 -11.39  -22.112 1 46.099  ? 242 ASN A HB2  1 c 
ATOM   3688 H HB3  . ASN A 1 242 ? -34.473 -9.817  -22.014 1 46.123  ? 242 ASN A HB3  1 c 
ATOM   3689 H HD21 . ASN A 1 242 ? -33.147 -11.354 -25.089 1 47.493  ? 242 ASN A HD21 1 c 
ATOM   3690 H HD22 . ASN A 1 242 ? -33.515 -12.312 -23.948 1 47.46   ? 242 ASN A HD22 1 c 
ATOM   3691 N N    . ALA A 1 243 ? -31.052 -9.204  -20.546 1 46.012  ? 243 ALA A N    1 ? 
ATOM   3692 C CA   . ALA A 1 243 ? -30.355 -7.971  -20.207 1 47.522  ? 243 ALA A CA   1 ? 
ATOM   3693 C C    . ALA A 1 243 ? -30.569 -6.839  -21.219 1 52.038  ? 243 ALA A C    1 ? 
ATOM   3694 O O    . ALA A 1 243 ? -30.311 -5.689  -20.88  1 56.093  ? 243 ALA A O    1 ? 
ATOM   3695 C CB   . ALA A 1 243 ? -28.875 -8.222  -20.041 1 47.763  ? 243 ALA A CB   1 ? 
ATOM   3696 H H    . ALA A 1 243 ? -30.557 -9.948  -20.735 1 46.899  ? 243 ALA A H    1 c 
ATOM   3697 H HA   . ALA A 1 243 ? -30.717 -7.661  -19.335 1 48.061  ? 243 ALA A HA   1 c 
ATOM   3698 H HB1  . ALA A 1 243 ? -28.736 -9.056  -19.564 1 47.743  ? 243 ALA A HB1  1 c 
ATOM   3699 H HB2  . ALA A 1 243 ? -28.451 -8.279  -20.914 1 47.79   ? 243 ALA A HB2  1 c 
ATOM   3700 H HB3  . ALA A 1 243 ? -28.474 -7.494  -19.537 1 47.72   ? 243 ALA A HB3  1 c 
ATOM   3701 N N    . TYR A 1 244 ? -30.938 -7.143  -22.468 1 52.636  ? 244 TYR A N    1 ? 
ATOM   3702 C CA   . TYR A 1 244 ? -31.187 -6.1    -23.457 1 51.823  ? 244 TYR A CA   1 ? 
ATOM   3703 C C    . TYR A 1 244 ? -32.672 -5.764  -23.509 1 52.273  ? 244 TYR A C    1 ? 
ATOM   3704 O O    . TYR A 1 244 ? -33.06  -4.629  -23.26  1 53.496  ? 244 TYR A O    1 ? 
ATOM   3705 C CB   . TYR A 1 244 ? -30.58  -6.527  -24.795 1 53.736  ? 244 TYR A CB   1 ? 
ATOM   3706 C CG   . TYR A 1 244 ? -29.117 -6.135  -24.967 1 66.854  ? 244 TYR A CG   1 ? 
ATOM   3707 C CD1  . TYR A 1 244 ? -28.314 -5.732  -23.893 1 70.773  ? 244 TYR A CD1  1 ? 
ATOM   3708 C CD2  . TYR A 1 244 ? -28.527 -6.174  -26.227 1 79.337  ? 244 TYR A CD2  1 ? 
ATOM   3709 C CE1  . TYR A 1 244 ? -26.98  -5.393  -24.075 1 78.061  ? 244 TYR A CE1  1 ? 
ATOM   3710 C CE2  . TYR A 1 244 ? -27.195 -5.83   -26.42  1 80.222  ? 244 TYR A CE2  1 ? 
ATOM   3711 C CZ   . TYR A 1 244 ? -26.421 -5.446  -25.342 1 75.859  ? 244 TYR A CZ   1 ? 
ATOM   3712 O OH   . TYR A 1 244 ? -25.127 -5.098  -25.556 1 76.387  ? 244 TYR A OH   1 ? 
ATOM   3713 H H    . TYR A 1 244 ? -31.027 -8.017  -22.718 1 52.329  ? 244 TYR A H    1 c 
ATOM   3714 H HA   . TYR A 1 244 ? -30.722 -5.275  -23.166 1 52.713  ? 244 TYR A HA   1 c 
ATOM   3715 H HB2  . TYR A 1 244 ? -30.66  -7.503  -24.882 1 55.98   ? 244 TYR A HB2  1 c 
ATOM   3716 H HB3  . TYR A 1 244 ? -31.101 -6.122  -25.518 1 56.045  ? 244 TYR A HB3  1 c 
ATOM   3717 H HD1  . TYR A 1 244 ? -28.671 -5.705  -23.023 1 70.823  ? 244 TYR A HD1  1 c 
ATOM   3718 H HD2  . TYR A 1 244 ? -29.044 -6.44   -26.97  1 76.259  ? 244 TYR A HD2  1 c 
ATOM   3719 H HE1  . TYR A 1 244 ? -26.456 -5.125  -23.34  1 75.715  ? 244 TYR A HE1  1 c 
ATOM   3720 H HE2  . TYR A 1 244 ? -26.819 -5.861  -27.283 1 78.771  ? 244 TYR A HE2  1 c 
ATOM   3721 N N    . SER A 1 245 ? -33.502 -6.771  -23.765 1 47.605  ? 245 SER A N    1 ? 
ATOM   3722 C CA   . SER A 1 245 ? -34.907 -6.541  -24.002 1 48.092  ? 245 SER A CA   1 ? 
ATOM   3723 C C    . SER A 1 245 ? -35.66  -6.227  -22.713 1 51.988  ? 245 SER A C    1 ? 
ATOM   3724 O O    . SER A 1 245 ? -36.706 -5.584  -22.784 1 44.968  ? 245 SER A O    1 ? 
ATOM   3725 C CB   . SER A 1 245 ? -35.497 -7.701  -24.716 1 49.429  ? 245 SER A CB   1 ? 
ATOM   3726 O OG   . SER A 1 245 ? -35.629 -8.806  -23.846 1 47.024  ? 245 SER A OG   1 ? 
ATOM   3727 H H    . SER A 1 245 ? -33.182 -7.627  -23.794 1 48.826  ? 245 SER A H    1 c 
ATOM   3728 H HA   . SER A 1 245 ? -34.988 -5.751  -24.596 1 48.98   ? 245 SER A HA   1 c 
ATOM   3729 H HB2  . SER A 1 245 ? -36.375 -7.455  -25.066 1 48.541  ? 245 SER A HB2  1 c 
ATOM   3730 H HB3  . SER A 1 245 ? -34.924 -7.944  -25.468 1 48.541  ? 245 SER A HB3  1 c 
ATOM   3731 N N    . LEU A 1 246 ? -35.153 -6.676  -21.552 1 43.678  ? 246 LEU A N    1 ? 
ATOM   3732 C CA   . LEU A 1 246 ? -35.939 -6.6    -20.329 1 43.575  ? 246 LEU A CA   1 ? 
ATOM   3733 C C    . LEU A 1 246 ? -35.212 -5.875  -19.197 1 41.513  ? 246 LEU A C    1 ? 
ATOM   3734 O O    . LEU A 1 246 ? -35.585 -6.022  -18.039 1 41.759  ? 246 LEU A O    1 ? 
ATOM   3735 C CB   . LEU A 1 246 ? -36.331 -8.011  -19.916 1 44.005  ? 246 LEU A CB   1 ? 
ATOM   3736 C CG   . LEU A 1 246 ? -37.412 -8.676  -20.76  1 46.339  ? 246 LEU A CG   1 ? 
ATOM   3737 C CD1  . LEU A 1 246 ? -37.506 -10.159 -20.395 1 45.65   ? 246 LEU A CD1  1 ? 
ATOM   3738 C CD2  . LEU A 1 246 ? -38.739 -7.99   -20.565 1 47.888  ? 246 LEU A CD2  1 ? 
ATOM   3739 H H    . LEU A 1 246 ? -34.32  -7.05   -21.521 1 45.565  ? 246 LEU A H    1 c 
ATOM   3740 H HA   . LEU A 1 246 ? -36.762 -6.087  -20.517 1 43.384  ? 246 LEU A HA   1 c 
ATOM   3741 H HB2  . LEU A 1 246 ? -35.527 -8.577  -19.942 1 44.44   ? 246 LEU A HB2  1 c 
ATOM   3742 H HB3  . LEU A 1 246 ? -36.642 -7.989  -18.984 1 44.43   ? 246 LEU A HB3  1 c 
ATOM   3743 H HG   . LEU A 1 246 ? -37.157 -8.601  -21.714 1 46.06   ? 246 LEU A HG   1 c 
ATOM   3744 H HD11 . LEU A 1 246 ? -36.647 -10.587 -20.549 1 45.844  ? 246 LEU A HD11 1 c 
ATOM   3745 H HD12 . LEU A 1 246 ? -38.183 -10.587 -20.946 1 45.859  ? 246 LEU A HD12 1 c 
ATOM   3746 H HD13 . LEU A 1 246 ? -37.749 -10.248 -19.458 1 45.851  ? 246 LEU A HD13 1 c 
ATOM   3747 H HD21 . LEU A 1 246 ? -38.763 -7.172  -21.09  1 47.373  ? 246 LEU A HD21 1 c 
ATOM   3748 H HD22 . LEU A 1 246 ? -38.862 -7.775  -19.626 1 47.364  ? 246 LEU A HD22 1 c 
ATOM   3749 H HD23 . LEU A 1 246 ? -39.456 -8.579  -20.856 1 47.369  ? 246 LEU A HD23 1 c 
ATOM   3750 N N    . TYR A 1 247 ? -34.206 -5.069  -19.529 1 46.41   ? 247 TYR A N    1 ? 
ATOM   3751 C CA   . TYR A 1 247 ? -33.54  -4.225  -18.552 1 52.223  ? 247 TYR A CA   1 ? 
ATOM   3752 C C    . TYR A 1 247 ? -33.78  -2.784  -18.972 1 57.101  ? 247 TYR A C    1 ? 
ATOM   3753 O O    . TYR A 1 247 ? -33.737 -2.463  -20.155 1 49.96   ? 247 TYR A O    1 ? 
ATOM   3754 C CB   . TYR A 1 247 ? -32.021 -4.392  -18.448 1 47.795  ? 247 TYR A CB   1 ? 
ATOM   3755 C CG   . TYR A 1 247 ? -31.49  -5.53   -17.584 1 48.083  ? 247 TYR A CG   1 ? 
ATOM   3756 C CD1  . TYR A 1 247 ? -32.331 -6.444  -16.957 1 47.862  ? 247 TYR A CD1  1 ? 
ATOM   3757 C CD2  . TYR A 1 247 ? -30.119 -5.704  -17.424 1 47.524  ? 247 TYR A CD2  1 ? 
ATOM   3758 C CE1  . TYR A 1 247 ? -31.832 -7.463  -16.163 1 46.506  ? 247 TYR A CE1  1 ? 
ATOM   3759 C CE2  . TYR A 1 247 ? -29.605 -6.738  -16.653 1 48.622  ? 247 TYR A CE2  1 ? 
ATOM   3760 C CZ   . TYR A 1 247 ? -30.465 -7.625  -16.025 1 46.924  ? 247 TYR A CZ   1 ? 
ATOM   3761 O OH   . TYR A 1 247 ? -30.019 -8.655  -15.243 1 48.216  ? 247 TYR A OH   1 ? 
ATOM   3762 H H    . TYR A 1 247 ? -33.923 -5.032  -20.396 1 46.373  ? 247 TYR A H    1 c 
ATOM   3763 H HA   . TYR A 1 247 ? -33.945 -4.365  -17.659 1 50.95   ? 247 TYR A HA   1 c 
ATOM   3764 H HB2  . TYR A 1 247 ? -31.671 -4.502  -19.355 1 48.895  ? 247 TYR A HB2  1 c 
ATOM   3765 H HB3  . TYR A 1 247 ? -31.645 -3.551  -18.104 1 48.894  ? 247 TYR A HB3  1 c 
ATOM   3766 H HD1  . TYR A 1 247 ? -33.263 -6.351  -17.036 1 47.574  ? 247 TYR A HD1  1 c 
ATOM   3767 H HD2  . TYR A 1 247 ? -29.525 -5.109  -17.852 1 47.896  ? 247 TYR A HD2  1 c 
ATOM   3768 H HE1  . TYR A 1 247 ? -32.422 -8.068  -15.744 1 46.948  ? 247 TYR A HE1  1 c 
ATOM   3769 H HE2  . TYR A 1 247 ? -28.675 -6.835  -16.558 1 48.003  ? 247 TYR A HE2  1 c 
ATOM   3770 N N    . PHE A 1 248 ? -33.971 -1.924  -17.978 1 53.542  ? 248 PHE A N    1 ? 
ATOM   3771 C CA   . PHE A 1 248 ? -34.088 -0.512  -18.257 1 61.426  ? 248 PHE A CA   1 ? 
ATOM   3772 C C    . PHE A 1 248 ? -33.593 0.251   -17.045 1 54.858  ? 248 PHE A C    1 ? 
ATOM   3773 O O    . PHE A 1 248 ? -33.983 -0.082  -15.93  1 52.13   ? 248 PHE A O    1 ? 
ATOM   3774 C CB   . PHE A 1 248 ? -35.539 -0.145  -18.569 1 60.993  ? 248 PHE A CB   1 ? 
ATOM   3775 C CG   . PHE A 1 248 ? -35.666 1.292   -19.044 1 64.303  ? 248 PHE A CG   1 ? 
ATOM   3776 C CD1  . PHE A 1 248 ? -35.211 1.655   -20.313 1 65.035  ? 248 PHE A CD1  1 ? 
ATOM   3777 C CD2  . PHE A 1 248 ? -36.224 2.27    -18.226 1 60.799  ? 248 PHE A CD2  1 ? 
ATOM   3778 C CE1  . PHE A 1 248 ? -35.323 2.962   -20.76  1 59.949  ? 248 PHE A CE1  1 ? 
ATOM   3779 C CE2  . PHE A 1 248 ? -36.336 3.577   -18.676 1 56.531  ? 248 PHE A CE2  1 ? 
ATOM   3780 C CZ   . PHE A 1 248 ? -35.885 3.92    -19.938 1 59.514  ? 248 PHE A CZ   1 ? 
ATOM   3781 H H    . PHE A 1 248 ? -34.034 -2.218  -17.114 1 56.002  ? 248 PHE A H    1 c 
ATOM   3782 H HA   . PHE A 1 248 ? -33.521 -0.285  -19.041 1 58.388  ? 248 PHE A HA   1 c 
ATOM   3783 H HB2  . PHE A 1 248 ? -35.877 -0.749  -19.267 1 61.799  ? 248 PHE A HB2  1 c 
ATOM   3784 H HB3  . PHE A 1 248 ? -36.08  -0.269  -17.757 1 61.773  ? 248 PHE A HB3  1 c 
ATOM   3785 H HD1  . PHE A 1 248 ? -34.83  0.999   -20.875 1 63.528  ? 248 PHE A HD1  1 c 
ATOM   3786 H HD2  . PHE A 1 248 ? -36.536 2.039   -17.365 1 60.569  ? 248 PHE A HD2  1 c 
ATOM   3787 H HE1  . PHE A 1 248 ? -35.015 3.196   -21.621 1 60.976  ? 248 PHE A HE1  1 c 
ATOM   3788 H HE2  . PHE A 1 248 ? -36.718 4.235   -18.118 1 58.28   ? 248 PHE A HE2  1 c 
ATOM   3789 H HZ   . PHE A 1 248 ? -35.96  4.811   -20.238 1 58.984  ? 248 PHE A HZ   1 c 
ATOM   3790 N N    . LEU A 1 249 ? -32.76  1.262   -17.313 1 51.653  ? 249 LEU A N    1 ? 
ATOM   3791 C CA   . LEU A 1 249 ? -32.171 2.112   -16.296 1 57.931  ? 249 LEU A CA   1 ? 
ATOM   3792 C C    . LEU A 1 249 ? -32.792 3.502   -16.412 1 58.774  ? 249 LEU A C    1 ? 
ATOM   3793 O O    . LEU A 1 249 ? -32.329 4.308   -17.218 1 55.53   ? 249 LEU A O    1 ? 
ATOM   3794 C CB   . LEU A 1 249 ? -30.655 2.134   -16.474 1 58.806  ? 249 LEU A CB   1 ? 
ATOM   3795 C CG   . LEU A 1 249 ? -29.931 0.891   -15.941 1 64.156  ? 249 LEU A CG   1 ? 
ATOM   3796 C CD1  . LEU A 1 249 ? -30.236 -0.336  -16.804 1 63.166  ? 249 LEU A CD1  1 ? 
ATOM   3797 C CD2  . LEU A 1 249 ? -28.425 1.083   -15.796 1 68.309  ? 249 LEU A CD2  1 ? 
ATOM   3798 H H    . LEU A 1 249 ? -32.551 1.437   -18.185 1 53.919  ? 249 LEU A H    1 c 
ATOM   3799 H HA   . LEU A 1 249 ? -32.38  1.74    -15.406 1 56.953  ? 249 LEU A HA   1 c 
ATOM   3800 H HB2  . LEU A 1 249 ? -30.454 2.231   -17.433 1 59.759  ? 249 LEU A HB2  1 c 
ATOM   3801 H HB3  . LEU A 1 249 ? -30.299 2.925   -16.007 1 59.793  ? 249 LEU A HB3  1 c 
ATOM   3802 H HG   . LEU A 1 249 ? -30.286 0.712   -15.036 1 63.55   ? 249 LEU A HG   1 c 
ATOM   3803 H HD11 . LEU A 1 249 ? -31.01  -0.801  -16.444 1 63.394  ? 249 LEU A HD11 1 c 
ATOM   3804 H HD12 . LEU A 1 249 ? -29.472 -0.937  -16.799 1 63.467  ? 249 LEU A HD12 1 c 
ATOM   3805 H HD13 . LEU A 1 249 ? -30.421 -0.06   -17.717 1 63.332  ? 249 LEU A HD13 1 c 
ATOM   3806 H HD21 . LEU A 1 249 ? -28.248 1.888   -15.28  1 67.053  ? 249 LEU A HD21 1 c 
ATOM   3807 H HD22 . LEU A 1 249 ? -28.021 1.168   -16.676 1 67.053  ? 249 LEU A HD22 1 c 
ATOM   3808 H HD23 . LEU A 1 249 ? -28.042 0.316   -15.338 1 67.034  ? 249 LEU A HD23 1 c 
ATOM   3809 N N    . PRO A 1 250 ? -33.864 3.814   -15.641 1 56.914  ? 250 PRO A N    1 ? 
ATOM   3810 C CA   . PRO A 1 250 ? -34.395 5.172   -15.589 1 61.457  ? 250 PRO A CA   1 ? 
ATOM   3811 C C    . PRO A 1 250 ? -33.307 6.208   -15.311 1 61.917  ? 250 PRO A C    1 ? 
ATOM   3812 O O    . PRO A 1 250 ? -32.425 5.958   -14.496 1 69.849  ? 250 PRO A O    1 ? 
ATOM   3813 C CB   . PRO A 1 250 ? -35.464 5.101   -14.505 1 56.312  ? 250 PRO A CB   1 ? 
ATOM   3814 C CG   . PRO A 1 250 ? -35.892 3.651   -14.538 1 62.217  ? 250 PRO A CG   1 ? 
ATOM   3815 C CD   . PRO A 1 250 ? -34.624 2.893   -14.785 1 58.426  ? 250 PRO A CD   1 ? 
ATOM   3816 H HA   . PRO A 1 250 ? -34.824 5.374   -16.446 1 59.778  ? 250 PRO A HA   1 c 
ATOM   3817 H HB2  . PRO A 1 250 ? -35.095 5.338   -13.632 1 58.758  ? 250 PRO A HB2  1 c 
ATOM   3818 H HB3  . PRO A 1 250 ? -36.212 5.693   -14.711 1 58.745  ? 250 PRO A HB3  1 c 
ATOM   3819 H HG2  . PRO A 1 250 ? -36.292 3.386   -13.688 1 59.923  ? 250 PRO A HG2  1 c 
ATOM   3820 H HG3  . PRO A 1 250 ? -36.536 3.492   -15.257 1 59.957  ? 250 PRO A HG3  1 c 
ATOM   3821 H HD2  . PRO A 1 250 ? -34.145 2.712   -13.953 1 58.871  ? 250 PRO A HD2  1 c 
ATOM   3822 H HD3  . PRO A 1 250 ? -34.804 2.059   -15.244 1 58.833  ? 250 PRO A HD3  1 c 
ATOM   3823 N N    . SER A 1 251 ? -33.396 7.343   -16.021 1 68.724  ? 251 SER A N    1 ? 
ATOM   3824 C CA   . SER A 1 251 ? -32.38  8.388   -16.072 1 70.087  ? 251 SER A CA   1 ? 
ATOM   3825 C C    . SER A 1 251 ? -33.055 9.753   -16.24  1 73.638  ? 251 SER A C    1 ? 
ATOM   3826 O O    . SER A 1 251 ? -34.087 9.865   -16.905 1 65.107  ? 251 SER A O    1 ? 
ATOM   3827 C CB   . SER A 1 251 ? -31.427 8.13    -17.215 1 70.81   ? 251 SER A CB   1 ? 
ATOM   3828 O OG   . SER A 1 251 ? -30.265 8.934   -17.096 1 76.955  ? 251 SER A OG   1 ? 
ATOM   3829 H H    . SER A 1 251 ? -34.157 7.477   -16.509 1 67.267  ? 251 SER A H    1 c 
ATOM   3830 H HA   . SER A 1 251 ? -31.876 8.384   -15.224 1 70.573  ? 251 SER A HA   1 c 
ATOM   3831 H HB2  . SER A 1 251 ? -31.171 7.188   -17.215 1 72.061  ? 251 SER A HB2  1 c 
ATOM   3832 H HB3  . SER A 1 251 ? -31.873 8.325   -18.061 1 72.069  ? 251 SER A HB3  1 c 
ATOM   3833 N N    . ASN A 1 252 ? -32.444 10.796  -15.66  1 81.481  ? 252 ASN A N    1 ? 
ATOM   3834 C CA   . ASN A 1 252 ? -32.967 12.153  -15.717 1 79.374  ? 252 ASN A CA   1 ? 
ATOM   3835 C C    . ASN A 1 252 ? -32.943 12.67   -17.157 1 81.829  ? 252 ASN A C    1 ? 
ATOM   3836 O O    . ASN A 1 252 ? -33.856 13.387  -17.565 1 79.612  ? 252 ASN A O    1 ? 
ATOM   3837 C CB   . ASN A 1 252 ? -32.217 13.058  -14.743 1 84.449  ? 252 ASN A CB   1 ? 
ATOM   3838 C CG   . ASN A 1 252 ? -32.864 14.413  -14.558 1 92.48   ? 252 ASN A CG   1 ? 
ATOM   3839 O OD1  . ASN A 1 252 ? -34.095 14.544  -14.584 1 74.842  ? 252 ASN A OD1  1 ? 
ATOM   3840 N ND2  . ASN A 1 252 ? -32.05  15.439  -14.364 1 102.981 ? 252 ASN A ND2  1 ? 
ATOM   3841 H H    . ASN A 1 252 ? -31.66  10.653  -15.213 1 78.967  ? 252 ASN A H    1 c 
ATOM   3842 H HA   . ASN A 1 252 ? -33.905 12.121  -15.422 1 80.992  ? 252 ASN A HA   1 c 
ATOM   3843 H HB2  . ASN A 1 252 ? -32.163 12.612  -13.874 1 85.045  ? 252 ASN A HB2  1 c 
ATOM   3844 H HB3  . ASN A 1 252 ? -31.304 13.186  -15.07  1 85.124  ? 252 ASN A HB3  1 c 
ATOM   3845 H HD21 . ASN A 1 252 ? -32.239 16.228  -14.722 1 99.601  ? 252 ASN A HD21 1 c 
ATOM   3846 H HD22 . ASN A 1 252 ? -31.316 15.336  -13.875 1 99.516  ? 252 ASN A HD22 1 c 
ATOM   3847 N N    . GLY A 1 253 ? -31.919 12.266  -17.925 1 80.839  ? 253 GLY A N    1 ? 
ATOM   3848 C CA   . GLY A 1 253 ? -31.753 12.657  -19.318 1 85.096  ? 253 GLY A CA   1 ? 
ATOM   3849 C C    . GLY A 1 253 ? -32.871 12.198  -20.263 1 88.165  ? 253 GLY A C    1 ? 
ATOM   3850 O O    . GLY A 1 253 ? -33.012 12.784  -21.336 1 88.056  ? 253 GLY A O    1 ? 
ATOM   3851 H H    . GLY A 1 253 ? -31.278 11.73   -17.555 1 82.001  ? 253 GLY A H    1 c 
ATOM   3852 H HA2  . GLY A 1 253 ? -31.688 13.64   -19.358 1 84.723  ? 253 GLY A HA2  1 c 
ATOM   3853 H HA3  . GLY A 1 253 ? -30.895 12.293  -19.641 1 84.723  ? 253 GLY A HA3  1 c 
ATOM   3854 N N    . PHE A 1 254 ? -33.655 11.166  -19.893 1 88.149  ? 254 PHE A N    1 ? 
ATOM   3855 C CA   . PHE A 1 254 ? -34.628 10.563  -20.804 1 84.668  ? 254 PHE A CA   1 ? 
ATOM   3856 C C    . PHE A 1 254 ? -35.905 11.409  -20.896 1 77.725  ? 254 PHE A C    1 ? 
ATOM   3857 O O    . PHE A 1 254 ? -36.427 11.886  -19.89  1 60.881  ? 254 PHE A O    1 ? 
ATOM   3858 C CB   . PHE A 1 254 ? -35.015 9.122   -20.43  1 81.484  ? 254 PHE A CB   1 ? 
ATOM   3859 C CG   . PHE A 1 254 ? -33.958 8.037   -20.636 1 83.052  ? 254 PHE A CG   1 ? 
ATOM   3860 C CD1  . PHE A 1 254 ? -33.028 8.095   -21.679 1 82.849  ? 254 PHE A CD1  1 ? 
ATOM   3861 C CD2  . PHE A 1 254 ? -33.891 6.947   -19.771 1 76.993  ? 254 PHE A CD2  1 ? 
ATOM   3862 C CE1  . PHE A 1 254 ? -32.067 7.104   -21.841 1 79.32   ? 254 PHE A CE1  1 ? 
ATOM   3863 C CE2  . PHE A 1 254 ? -32.931 5.954   -19.946 1 76.225  ? 254 PHE A CE2  1 ? 
ATOM   3864 C CZ   . PHE A 1 254 ? -32.023 6.033   -20.979 1 74.302  ? 254 PHE A CZ   1 ? 
ATOM   3865 H H    . PHE A 1 254 ? -33.57  10.811  -19.056 1 87.276  ? 254 PHE A H    1 c 
ATOM   3866 H HA   . PHE A 1 254 ? -34.218 10.542  -21.703 1 83.442  ? 254 PHE A HA   1 c 
ATOM   3867 H HB2  . PHE A 1 254 ? -35.279 9.116   -19.485 1 82.431  ? 254 PHE A HB2  1 c 
ATOM   3868 H HB3  . PHE A 1 254 ? -35.813 8.875   -20.949 1 82.503  ? 254 PHE A HB3  1 c 
ATOM   3869 H HD1  . PHE A 1 254 ? -33.044 8.822   -22.278 1 81.946  ? 254 PHE A HD1  1 c 
ATOM   3870 H HD2  . PHE A 1 254 ? -34.508 6.88    -19.06  1 78.187  ? 254 PHE A HD2  1 c 
ATOM   3871 H HE1  . PHE A 1 254 ? -31.45  7.161   -22.553 1 78.902  ? 254 PHE A HE1  1 c 
ATOM   3872 H HE2  . PHE A 1 254 ? -32.905 5.223   -19.358 1 75.877  ? 254 PHE A HE2  1 c 
ATOM   3873 H HZ   . PHE A 1 254 ? -31.375 5.356   -21.094 1 75.993  ? 254 PHE A HZ   1 c 
ATOM   3874 N N    . THR A 1 255 ? -36.433 11.527  -22.122 1 80.976  ? 255 THR A N    1 ? 
ATOM   3875 C CA   . THR A 1 255 ? -37.666 12.244  -22.413 1 86.91   ? 255 THR A CA   1 ? 
ATOM   3876 C C    . THR A 1 255 ? -38.758 11.227  -22.746 1 88.037  ? 255 THR A C    1 ? 
ATOM   3877 O O    . THR A 1 255 ? -38.521 10.023  -22.651 1 82.447  ? 255 THR A O    1 ? 
ATOM   3878 C CB   . THR A 1 255 ? -37.389 13.193  -23.582 1 90.973  ? 255 THR A CB   1 ? 
ATOM   3879 O OG1  . THR A 1 255 ? -37.135 12.353  -24.706 1 83.244  ? 255 THR A OG1  1 ? 
ATOM   3880 C CG2  . THR A 1 255 ? -36.204 14.111  -23.333 1 88.813  ? 255 THR A CG2  1 ? 
ATOM   3881 H H    . THR A 1 255 ? -35.996 11.135  -22.822 1 81.564  ? 255 THR A H    1 c 
ATOM   3882 H HA   . THR A 1 255 ? -37.936 12.769  -21.63  1 86.415  ? 255 THR A HA   1 c 
ATOM   3883 H HB   . THR A 1 255 ? -38.185 13.749  -23.763 1 88.213  ? 255 THR A HB   1 c 
ATOM   3884 H HG21 . THR A 1 255 ? -36.275 14.896  -23.902 1 89.442  ? 255 THR A HG21 1 c 
ATOM   3885 H HG22 . THR A 1 255 ? -35.379 13.638  -23.537 1 89.441  ? 255 THR A HG22 1 c 
ATOM   3886 H HG23 . THR A 1 255 ? -36.196 14.386  -22.401 1 89.431  ? 255 THR A HG23 1 c 
ATOM   3887 N N    . GLN A 1 256 ? -39.929 11.726  -23.175 1 82.259  ? 256 GLN A N    1 ? 
ATOM   3888 C CA   . GLN A 1 256 ? -41.045 10.904  -23.633 1 77.862  ? 256 GLN A CA   1 ? 
ATOM   3889 C C    . GLN A 1 256 ? -40.684 10.104  -24.891 1 75.955  ? 256 GLN A C    1 ? 
ATOM   3890 O O    . GLN A 1 256 ? -41.104 8.95    -25.022 1 63.749  ? 256 GLN A O    1 ? 
ATOM   3891 C CB   . GLN A 1 256 ? -42.262 11.788  -23.927 1 83.744  ? 256 GLN A CB   1 ? 
ATOM   3892 C CG   . GLN A 1 256 ? -43.552 11.027  -24.228 1 89.339  ? 256 GLN A CG   1 ? 
ATOM   3893 C CD   . GLN A 1 256 ? -44.063 10.24   -23.041 1 92.931  ? 256 GLN A CD   1 ? 
ATOM   3894 O OE1  . GLN A 1 256 ? -44.339 10.799  -21.97  1 88.302  ? 256 GLN A OE1  1 ? 
ATOM   3895 N NE2  . GLN A 1 256 ? -44.183 8.931   -23.224 1 94.926  ? 256 GLN A NE2  1 ? 
ATOM   3896 H H    . GLN A 1 256 ? -40.047 12.633  -23.16  1 82.701  ? 256 GLN A H    1 c 
ATOM   3897 H HA   . GLN A 1 256 ? -41.272 10.267  -22.91  1 79.446  ? 256 GLN A HA   1 c 
ATOM   3898 H HB2  . GLN A 1 256 ? -42.415 12.372  -23.155 1 83.577  ? 256 GLN A HB2  1 c 
ATOM   3899 H HB3  . GLN A 1 256 ? -42.05  12.362  -24.693 1 83.547  ? 256 GLN A HB3  1 c 
ATOM   3900 H HG2  . GLN A 1 256 ? -44.245 11.666  -24.499 1 88.839  ? 256 GLN A HG2  1 c 
ATOM   3901 H HG3  . GLN A 1 256 ? -43.405 10.415  -24.979 1 88.814  ? 256 GLN A HG3  1 c 
ATOM   3902 H HE21 . GLN A 1 256 ? -43.83  8.368   -22.636 1 94.308  ? 256 GLN A HE21 1 c 
ATOM   3903 H HE22 . GLN A 1 256 ? -44.615 8.621   -23.933 1 94.308  ? 256 GLN A HE22 1 c 
ATOM   3904 N N    . GLU A 1 257 ? -39.928 10.735  -25.808 1 71.261  ? 257 GLU A N    1 ? 
ATOM   3905 C CA   . GLU A 1 257 ? -39.591 10.154  -27.101 1 75.926  ? 257 GLU A CA   1 ? 
ATOM   3906 C C    . GLU A 1 257 ? -38.658 8.958   -26.893 1 74.925  ? 257 GLU A C    1 ? 
ATOM   3907 O O    . GLU A 1 257 ? -38.76  7.965   -27.605 1 73.94   ? 257 GLU A O    1 ? 
ATOM   3908 C CB   . GLU A 1 257 ? -38.996 11.224  -28.03  1 81.157  ? 257 GLU A CB   1 ? 
ATOM   3909 C CG   . GLU A 1 257 ? -39.378 11.069  -29.504 1 96.492  ? 257 GLU A CG   1 ? 
ATOM   3910 C CD   . GLU A 1 257 ? -38.502 10.252  -30.457 1 102.811 ? 257 GLU A CD   1 ? 
ATOM   3911 O OE1  . GLU A 1 257 ? -37.309 10.012  -30.15  1 93.493  ? 257 GLU A OE1  1 ? 
ATOM   3912 O OE2  . GLU A 1 257 ? -39.028 9.855   -31.534 1 90.211  ? 257 GLU A OE2  1 ? 
ATOM   3913 H H    . GLU A 1 257 ? -39.609 11.569  -25.613 1 73.612  ? 257 GLU A H    1 c 
ATOM   3914 H HA   . GLU A 1 257 ? -40.43  9.818   -27.507 1 75.873  ? 257 GLU A HA   1 c 
ATOM   3915 H HB2  . GLU A 1 257 ? -39.307 12.106  -27.74  1 83.048  ? 257 GLU A HB2  1 c 
ATOM   3916 H HB3  . GLU A 1 257 ? -38.02  11.212  -27.944 1 83.13   ? 257 GLU A HB3  1 c 
ATOM   3917 H HG2  . GLU A 1 257 ? -40.281 10.689  -29.544 1 93.85   ? 257 GLU A HG2  1 c 
ATOM   3918 H HG3  . GLU A 1 257 ? -39.454 11.97   -29.885 1 94.051  ? 257 GLU A HG3  1 c 
ATOM   3919 N N    . ASP A 1 258 ? -37.776 9.056   -25.887 1 70.295  ? 258 ASP A N    1 ? 
ATOM   3920 C CA   . ASP A 1 258 ? -36.892 7.971   -25.499 1 68.186  ? 258 ASP A CA   1 ? 
ATOM   3921 C C    . ASP A 1 258 ? -37.714 6.781   -24.994 1 68.235  ? 258 ASP A C    1 ? 
ATOM   3922 O O    . ASP A 1 258 ? -37.418 5.637   -25.343 1 61.878  ? 258 ASP A O    1 ? 
ATOM   3923 C CB   . ASP A 1 258 ? -35.886 8.439   -24.461 1 73.004  ? 258 ASP A CB   1 ? 
ATOM   3924 C CG   . ASP A 1 258 ? -34.939 9.553   -24.897 1 78.007  ? 258 ASP A CG   1 ? 
ATOM   3925 O OD1  . ASP A 1 258 ? -34.185 9.344   -25.874 1 70.506  ? 258 ASP A OD1  1 ? 
ATOM   3926 O OD2  . ASP A 1 258 ? -34.949 10.621  -24.242 1 86.514  ? 258 ASP A OD2  1 ? 
ATOM   3927 H H    . ASP A 1 258 ? -37.717 9.845   -25.429 1 70.964  ? 258 ASP A H    1 c 
ATOM   3928 H HA   . ASP A 1 258 ? -36.39  7.686   -26.296 1 69.476  ? 258 ASP A HA   1 c 
ATOM   3929 H HB2  . ASP A 1 258 ? -36.377 8.747   -23.671 1 73.091  ? 258 ASP A HB2  1 c 
ATOM   3930 H HB3  . ASP A 1 258 ? -35.342 7.67    -24.191 1 72.994  ? 258 ASP A HB3  1 c 
ATOM   3931 N N    . ILE A 1 259 ? -38.762 7.058   -24.202 1 54.823  ? 259 ILE A N    1 ? 
ATOM   3932 C CA   . ILE A 1 259 ? -39.614 6.01    -23.664 1 55.72   ? 259 ILE A CA   1 ? 
ATOM   3933 C C    . ILE A 1 259 ? -40.406 5.378   -24.804 1 59.293  ? 259 ILE A C    1 ? 
ATOM   3934 O O    . ILE A 1 259 ? -40.597 4.16    -24.802 1 63.156  ? 259 ILE A O    1 ? 
ATOM   3935 C CB   . ILE A 1 259 ? -40.515 6.531   -22.525 1 58.463  ? 259 ILE A CB   1 ? 
ATOM   3936 C CG1  . ILE A 1 259 ? -39.704 7.163   -21.379 1 63.113  ? 259 ILE A CG1  1 ? 
ATOM   3937 C CG2  . ILE A 1 259 ? -41.452 5.442   -21.999 1 64.294  ? 259 ILE A CG2  1 ? 
ATOM   3938 C CD1  . ILE A 1 259 ? -38.574 6.312   -20.817 1 61.598  ? 259 ILE A CD1  1 ? 
ATOM   3939 H H    . ILE A 1 259 ? -38.949 7.927   -23.991 1 58.25   ? 259 ILE A H    1 c 
ATOM   3940 H HA   . ILE A 1 259 ? -39.035 5.319   -23.289 1 56.854  ? 259 ILE A HA   1 c 
ATOM   3941 H HB   . ILE A 1 259 ? -41.076 7.238   -22.903 1 59.832  ? 259 ILE A HB   1 c 
ATOM   3942 H HG12 . ILE A 1 259 ? -39.324 8.003   -21.698 1 61.742  ? 259 ILE A HG12 1 c 
ATOM   3943 H HG13 . ILE A 1 259 ? -40.318 7.381   -20.649 1 61.702  ? 259 ILE A HG13 1 c 
ATOM   3944 H HG21 . ILE A 1 259 ? -41.706 5.639   -21.082 1 62.496  ? 259 ILE A HG21 1 c 
ATOM   3945 H HG22 . ILE A 1 259 ? -41.001 4.582   -22.03  1 62.425  ? 259 ILE A HG22 1 c 
ATOM   3946 H HG23 . ILE A 1 259 ? -42.251 5.406   -22.551 1 62.472  ? 259 ILE A HG23 1 c 
ATOM   3947 H HD11 . ILE A 1 259 ? -38.901 5.407   -20.651 1 62.035  ? 259 ILE A HD11 1 c 
ATOM   3948 H HD12 . ILE A 1 259 ? -38.25  6.695   -19.982 1 62.028  ? 259 ILE A HD12 1 c 
ATOM   3949 H HD13 . ILE A 1 259 ? -37.841 6.277   -21.46  1 61.974  ? 259 ILE A HD13 1 c 
ATOM   3950 N N    . ASN A 1 260 ? -40.815 6.198   -25.786 1 61.8    ? 260 ASN A N    1 ? 
ATOM   3951 C CA   . ASN A 1 260 ? -41.519 5.704   -26.961 1 63.906  ? 260 ASN A CA   1 ? 
ATOM   3952 C C    . ASN A 1 260 ? -40.624 4.745   -27.749 1 59.905  ? 260 ASN A C    1 ? 
ATOM   3953 O O    . ASN A 1 260 ? -41.077 3.686   -28.17  1 51.835  ? 260 ASN A O    1 ? 
ATOM   3954 C CB   . ASN A 1 260 ? -42.047 6.846   -27.822 1 65.231  ? 260 ASN A CB   1 ? 
ATOM   3955 C CG   . ASN A 1 260 ? -43.067 7.702   -27.099 1 72.897  ? 260 ASN A CG   1 ? 
ATOM   3956 O OD1  . ASN A 1 260 ? -43.511 7.379   -25.987 1 71.908  ? 260 ASN A OD1  1 ? 
ATOM   3957 N ND2  . ASN A 1 260 ? -43.426 8.825   -27.702 1 73.384  ? 260 ASN A ND2  1 ? 
ATOM   3958 H H    . ASN A 1 260 ? -40.659 7.095   -25.716 1 61.641  ? 260 ASN A H    1 c 
ATOM   3959 H HA   . ASN A 1 260 ? -42.297 5.193   -26.65  1 62.906  ? 260 ASN A HA   1 c 
ATOM   3960 H HB2  . ASN A 1 260 ? -41.298 7.41    -28.1   1 66.642  ? 260 ASN A HB2  1 c 
ATOM   3961 H HB3  . ASN A 1 260 ? -42.458 6.475   -28.628 1 66.612  ? 260 ASN A HB3  1 c 
ATOM   3962 H HD21 . ASN A 1 260 ? -44.045 9.344   -27.336 1 73.209  ? 260 ASN A HD21 1 c 
ATOM   3963 H HD22 . ASN A 1 260 ? -43.051 9.059   -28.472 1 73.17   ? 260 ASN A HD22 1 c 
ATOM   3964 N N    . GLU A 1 261 ? -39.354 5.129   -27.937 1 61.137  ? 261 GLU A N    1 ? 
ATOM   3965 C CA   . GLU A 1 261 ? -38.385 4.301   -28.633 1 55.005  ? 261 GLU A CA   1 ? 
ATOM   3966 C C    . GLU A 1 261 ? -38.183 2.982   -27.884 1 56.226  ? 261 GLU A C    1 ? 
ATOM   3967 O O    . GLU A 1 261 ? -38.109 1.939   -28.526 1 53.049  ? 261 GLU A O    1 ? 
ATOM   3968 C CB   . GLU A 1 261 ? -37.07  5.06    -28.806 1 55.162  ? 261 GLU A CB   1 ? 
ATOM   3969 C CG   . GLU A 1 261 ? -35.972 4.22    -29.457 1 59.491  ? 261 GLU A CG   1 ? 
ATOM   3970 C CD   . GLU A 1 261 ? -34.639 4.932   -29.627 1 63.786  ? 261 GLU A CD   1 ? 
ATOM   3971 O OE1  . GLU A 1 261 ? -33.665 4.241   -30.007 1 66.022  ? 261 GLU A OE1  1 ? 
ATOM   3972 O OE2  . GLU A 1 261 ? -34.569 6.159   -29.379 1 57.535  ? 261 GLU A OE2  1 ? 
ATOM   3973 H H    . GLU A 1 261 ? -39.086 5.947   -27.629 1 59.417  ? 261 GLU A H    1 c 
ATOM   3974 H HA   . GLU A 1 261 ? -38.746 4.097   -29.533 1 56.387  ? 261 GLU A HA   1 c 
ATOM   3975 H HB2  . GLU A 1 261 ? -37.235 5.854   -29.355 1 56.092  ? 261 GLU A HB2  1 c 
ATOM   3976 H HB3  . GLU A 1 261 ? -36.762 5.363   -27.927 1 56.11   ? 261 GLU A HB3  1 c 
ATOM   3977 H HG2  . GLU A 1 261 ? -35.817 3.418   -28.916 1 59.413  ? 261 GLU A HG2  1 c 
ATOM   3978 H HG3  . GLU A 1 261 ? -36.281 3.923   -30.337 1 59.418  ? 261 GLU A HG3  1 c 
ATOM   3979 N N    . GLN A 1 262 ? -38.118 3.031   -26.538 1 52.284  ? 262 GLN A N    1 ? 
ATOM   3980 C CA   . GLN A 1 262 ? -37.953 1.825   -25.734 1 51.569  ? 262 GLN A CA   1 ? 
ATOM   3981 C C    . GLN A 1 262 ? -39.086 0.84    -26.022 1 50.666  ? 262 GLN A C    1 ? 
ATOM   3982 O O    . GLN A 1 262 ? -38.858 -0.36   -26.204 1 50.058  ? 262 GLN A O    1 ? 
ATOM   3983 C CB   . GLN A 1 262 ? -37.926 2.099   -24.229 1 54.078  ? 262 GLN A CB   1 ? 
ATOM   3984 C CG   . GLN A 1 262 ? -37.53  0.888   -23.386 1 53.008  ? 262 GLN A CG   1 ? 
ATOM   3985 C CD   . GLN A 1 262 ? -36.1   0.453   -23.608 1 55.626  ? 262 GLN A CD   1 ? 
ATOM   3986 O OE1  . GLN A 1 262 ? -35.22  1.255   -23.938 1 52.942  ? 262 GLN A OE1  1 ? 
ATOM   3987 N NE2  . GLN A 1 262 ? -35.846 -0.826  -23.392 1 61.37   ? 262 GLN A NE2  1 ? 
ATOM   3988 H H    . GLN A 1 262 ? -38.165 3.838   -26.112 1 53.104  ? 262 GLN A H    1 c 
ATOM   3989 H HA   . GLN A 1 262 ? -37.098 1.4     -25.998 1 52.004  ? 262 GLN A HA   1 c 
ATOM   3990 H HB2  . GLN A 1 262 ? -37.298 2.83    -24.053 1 53.258  ? 262 GLN A HB2  1 c 
ATOM   3991 H HB3  . GLN A 1 262 ? -38.815 2.4     -23.95  1 53.282  ? 262 GLN A HB3  1 c 
ATOM   3992 H HG2  . GLN A 1 262 ? -37.645 1.107   -22.436 1 53.848  ? 262 GLN A HG2  1 c 
ATOM   3993 H HG3  . GLN A 1 262 ? -38.125 0.136   -23.589 1 53.867  ? 262 GLN A HG3  1 c 
ATOM   3994 H HE21 . GLN A 1 262 ? -35.31  -1.27   -23.942 1 59.53   ? 262 GLN A HE21 1 c 
ATOM   3995 H HE22 . GLN A 1 262 ? -36.211 -1.239  -22.696 1 59.494  ? 262 GLN A HE22 1 c 
ATOM   3996 N N    . MET A 1 263 ? -40.305 1.376   -26.095 1 45.998  ? 263 MET A N    1 ? 
ATOM   3997 C CA   . MET A 1 263 ? -41.486 0.571   -26.356 1 49.694  ? 263 MET A CA   1 ? 
ATOM   3998 C C    . MET A 1 263 ? -41.486 0.009   -27.781 1 54.16   ? 263 MET A C    1 ? 
ATOM   3999 O O    . MET A 1 263 ? -41.864 -1.152  -27.967 1 50.225  ? 263 MET A O    1 ? 
ATOM   4000 C CB   . MET A 1 263 ? -42.731 1.397   -26.046 1 53.562  ? 263 MET A CB   1 ? 
ATOM   4001 C CG   . MET A 1 263 ? -42.854 1.686   -24.558 1 53.82   ? 263 MET A CG   1 ? 
ATOM   4002 S SD   . MET A 1 263 ? -44.447 2.414   -24.14  1 61.094  ? 263 MET A SD   1 ? 
ATOM   4003 C CE   . MET A 1 263 ? -44.092 4.066   -24.759 1 60.225  ? 263 MET A CE   1 ? 
ATOM   4004 H H    . MET A 1 263 ? -40.409 2.274   -25.965 1 48.051  ? 263 MET A H    1 c 
ATOM   4005 H HA   . MET A 1 263 ? -41.462 -0.202  -25.735 1 50.446  ? 263 MET A HA   1 c 
ATOM   4006 H HB2  . MET A 1 263 ? -42.685 2.244   -26.539 1 52.68   ? 263 MET A HB2  1 c 
ATOM   4007 H HB3  . MET A 1 263 ? -43.525 0.91    -26.351 1 52.718  ? 263 MET A HB3  1 c 
ATOM   4008 H HG2  . MET A 1 263 ? -42.749 0.853   -24.057 1 55.047  ? 263 MET A HG2  1 c 
ATOM   4009 H HG3  . MET A 1 263 ? -42.145 2.292   -24.282 1 55.099  ? 263 MET A HG3  1 c 
ATOM   4010 H HE1  . MET A 1 263 ? -44.773 4.685   -24.437 1 60.442  ? 263 MET A HE1  1 c 
ATOM   4011 H HE2  . MET A 1 263 ? -43.217 4.353   -24.44  1 60.433  ? 263 MET A HE2  1 c 
ATOM   4012 H HE3  . MET A 1 263 ? -44.099 4.054   -25.733 1 60.456  ? 263 MET A HE3  1 c 
ATOM   4013 N N    . ASP A 1 264 ? -41.029 0.795   -28.772 1 53.433  ? 264 ASP A N    1 ? 
ATOM   4014 C CA   . ASP A 1 264 ? -40.908 0.283   -30.137 1 56.174  ? 264 ASP A CA   1 ? 
ATOM   4015 C C    . ASP A 1 264 ? -39.846 -0.826  -30.215 1 58.579  ? 264 ASP A C    1 ? 
ATOM   4016 O O    . ASP A 1 264 ? -39.99  -1.777  -30.98  1 52.695  ? 264 ASP A O    1 ? 
ATOM   4017 C CB   . ASP A 1 264 ? -40.599 1.379   -31.151 1 53.678  ? 264 ASP A CB   1 ? 
ATOM   4018 C CG   . ASP A 1 264 ? -41.619 2.507   -31.25  1 53.301  ? 264 ASP A CG   1 ? 
ATOM   4019 O OD1  . ASP A 1 264 ? -42.835 2.206   -31.297 1 55.672  ? 264 ASP A OD1  1 ? 
ATOM   4020 O OD2  . ASP A 1 264 ? -41.195 3.678   -31.269 1 51.329  ? 264 ASP A OD2  1 ? 
ATOM   4021 H H    . ASP A 1 264 ? -40.796 1.662   -28.6   1 54.112  ? 264 ASP A H    1 c 
ATOM   4022 H HA   . ASP A 1 264 ? -41.775 -0.105  -30.394 1 55.547  ? 264 ASP A HA   1 c 
ATOM   4023 H HB2  . ASP A 1 264 ? -39.726 1.768   -30.937 1 54.136  ? 264 ASP A HB2  1 c 
ATOM   4024 H HB3  . ASP A 1 264 ? -40.533 0.954   -32.029 1 54.168  ? 264 ASP A HB3  1 c 
ATOM   4025 N N    . TYR A 1 265 ? -38.757 -0.672  -29.45  1 57.013  ? 265 TYR A N    1 ? 
ATOM   4026 C CA   . TYR A 1 265 ? -37.695 -1.665  -29.38  1 57.601  ? 265 TYR A CA   1 ? 
ATOM   4027 C C    . TYR A 1 265 ? -38.211 -2.979  -28.781 1 52.601  ? 265 TYR A C    1 ? 
ATOM   4028 O O    . TYR A 1 265 ? -37.987 -4.055  -29.333 1 55.089  ? 265 TYR A O    1 ? 
ATOM   4029 C CB   . TYR A 1 265 ? -36.543 -1.044  -28.587 1 58.165  ? 265 TYR A CB   1 ? 
ATOM   4030 C CG   . TYR A 1 265 ? -35.512 -2.059  -28.131 1 58.93   ? 265 TYR A CG   1 ? 
ATOM   4031 C CD1  . TYR A 1 265 ? -34.67  -2.674  -29.048 1 62.086  ? 265 TYR A CD1  1 ? 
ATOM   4032 C CD2  . TYR A 1 265 ? -35.374 -2.388  -26.79  1 61.116  ? 265 TYR A CD2  1 ? 
ATOM   4033 C CE1  . TYR A 1 265 ? -33.729 -3.605  -28.645 1 67.837  ? 265 TYR A CE1  1 ? 
ATOM   4034 C CE2  . TYR A 1 265 ? -34.425 -3.309  -26.37  1 62.279  ? 265 TYR A CE2  1 ? 
ATOM   4035 C CZ   . TYR A 1 265 ? -33.61  -3.925  -27.302 1 67.108  ? 265 TYR A CZ   1 ? 
ATOM   4036 O OH   . TYR A 1 265 ? -32.67  -4.827  -26.919 1 64.644  ? 265 TYR A OH   1 ? 
ATOM   4037 H H    . TYR A 1 265 ? -38.666 0.098   -28.966 1 57.487  ? 265 TYR A H    1 c 
ATOM   4038 H HA   . TYR A 1 265 ? -37.378 -1.844  -30.301 1 56.645  ? 265 TYR A HA   1 c 
ATOM   4039 H HB2  . TYR A 1 265 ? -36.101 -0.372  -29.152 1 58.204  ? 265 TYR A HB2  1 c 
ATOM   4040 H HB3  . TYR A 1 265 ? -36.907 -0.587  -27.8   1 58.181  ? 265 TYR A HB3  1 c 
ATOM   4041 H HD1  . TYR A 1 265 ? -34.752 -2.466  -29.965 1 62.63   ? 265 TYR A HD1  1 c 
ATOM   4042 H HD2  . TYR A 1 265 ? -35.932 -1.975  -26.151 1 60.919  ? 265 TYR A HD2  1 c 
ATOM   4043 H HE1  . TYR A 1 265 ? -33.167 -4.016  -29.279 1 66.149  ? 265 TYR A HE1  1 c 
ATOM   4044 H HE2  . TYR A 1 265 ? -34.347 -3.526  -25.456 1 63.08   ? 265 TYR A HE2  1 c 
ATOM   4045 N N    . MET A 1 266 ? -38.927 -2.87   -27.664 1 49.676  ? 266 MET A N    1 ? 
ATOM   4046 C CA   . MET A 1 266 ? -39.48  -4.018  -26.965 1 55.84   ? 266 MET A CA   1 ? 
ATOM   4047 C C    . MET A 1 266 ? -40.459 -4.793  -27.845 1 58.591  ? 266 MET A C    1 ? 
ATOM   4048 O O    . MET A 1 266 ? -40.57  -6.005  -27.709 1 55.332  ? 266 MET A O    1 ? 
ATOM   4049 C CB   . MET A 1 266 ? -40.245 -3.562  -25.719 1 60.541  ? 266 MET A CB   1 ? 
ATOM   4050 C CG   . MET A 1 266 ? -39.367 -3.197  -24.529 1 64.931  ? 266 MET A CG   1 ? 
ATOM   4051 S SD   . MET A 1 266 ? -40.324 -2.748  -23.063 1 65.278  ? 266 MET A SD   1 ? 
ATOM   4052 C CE   . MET A 1 266 ? -41.136 -4.313  -22.73  1 69.327  ? 266 MET A CE   1 ? 
ATOM   4053 H H    . MET A 1 266 ? -39.065 -2.039  -27.31  1 51.899  ? 266 MET A H    1 c 
ATOM   4054 H HA   . MET A 1 266 ? -38.737 -4.617  -26.701 1 55.864  ? 266 MET A HA   1 c 
ATOM   4055 H HB2  . MET A 1 266 ? -40.791 -2.783  -25.957 1 60.349  ? 266 MET A HB2  1 c 
ATOM   4056 H HB3  . MET A 1 266 ? -40.858 -4.279  -25.455 1 60.465  ? 266 MET A HB3  1 c 
ATOM   4057 H HG2  . MET A 1 266 ? -38.794 -3.958  -24.307 1 63.9    ? 266 MET A HG2  1 c 
ATOM   4058 H HG3  . MET A 1 266 ? -38.789 -2.449  -24.769 1 63.826  ? 266 MET A HG3  1 c 
ATOM   4059 H HE1  . MET A 1 266 ? -42.101 -4.184  -22.756 1 67.744  ? 266 MET A HE1  1 c 
ATOM   4060 H HE2  . MET A 1 266 ? -40.876 -4.97   -23.401 1 67.977  ? 266 MET A HE2  1 c 
ATOM   4061 H HE3  . MET A 1 266 ? -40.854 -4.638  -21.857 1 67.845  ? 266 MET A HE3  1 c 
ATOM   4062 N N    . ASN A 1 267 ? -41.21  -4.076  -28.692 1 54.035  ? 267 ASN A N    1 ? 
ATOM   4063 C CA   . ASN A 1 267 ? -42.118 -4.684  -29.642 1 52.857  ? 267 ASN A CA   1 ? 
ATOM   4064 C C    . ASN A 1 267 ? -41.471 -5.808  -30.444 1 48.991  ? 267 ASN A C    1 ? 
ATOM   4065 O O    . ASN A 1 267 ? -42.127 -6.802  -30.729 1 47.54   ? 267 ASN A O    1 ? 
ATOM   4066 C CB   . ASN A 1 267 ? -42.64  -3.68   -30.663 1 58.419  ? 267 ASN A CB   1 ? 
ATOM   4067 C CG   . ASN A 1 267 ? -43.73  -2.796  -30.113 1 58.222  ? 267 ASN A CG   1 ? 
ATOM   4068 O OD1  . ASN A 1 267 ? -44.251 -3.041  -29.021 1 55.413  ? 267 ASN A OD1  1 ? 
ATOM   4069 N ND2  . ASN A 1 267 ? -44.097 -1.776  -30.873 1 57.946  ? 267 ASN A ND2  1 ? 
ATOM   4070 H H    . ASN A 1 267 ? -41.165 -3.164  -28.662 1 54.802  ? 267 ASN A H    1 c 
ATOM   4071 H HA   . ASN A 1 267 ? -42.885 -5.054  -29.15  1 53.359  ? 267 ASN A HA   1 c 
ATOM   4072 H HB2  . ASN A 1 267 ? -41.903 -3.122  -30.969 1 57.025  ? 267 ASN A HB2  1 c 
ATOM   4073 H HB3  . ASN A 1 267 ? -42.99  -4.163  -31.438 1 57.006  ? 267 ASN A HB3  1 c 
ATOM   4074 H HD21 . ASN A 1 267 ? -44.851 -1.343  -30.696 1 58.01   ? 267 ASN A HD21 1 c 
ATOM   4075 H HD22 . ASN A 1 267 ? -43.591 -1.524  -31.557 1 58.024  ? 267 ASN A HD22 1 c 
ATOM   4076 N N    . TRP A 1 268 ? -40.236 -5.621  -30.903 1 51.798  ? 268 TRP A N    1 ? 
ATOM   4077 C CA   . TRP A 1 268 ? -39.596 -6.674  -31.683 1 56.64   ? 268 TRP A CA   1 ? 
ATOM   4078 C C    . TRP A 1 268 ? -38.596 -7.489  -30.846 1 52.038  ? 268 TRP A C    1 ? 
ATOM   4079 O O    . TRP A 1 268 ? -38.46  -8.674  -31.109 1 47.22   ? 268 TRP A O    1 ? 
ATOM   4080 C CB   . TRP A 1 268 ? -38.966 -6.096  -32.958 1 58.29   ? 268 TRP A CB   1 ? 
ATOM   4081 C CG   . TRP A 1 268 ? -37.8   -5.183  -32.717 1 57.33   ? 268 TRP A CG   1 ? 
ATOM   4082 C CD1  . TRP A 1 268 ? -37.808 -3.828  -32.577 1 56.651  ? 268 TRP A CD1  1 ? 
ATOM   4083 C CD2  . TRP A 1 268 ? -36.429 -5.606  -32.569 1 58.161  ? 268 TRP A CD2  1 ? 
ATOM   4084 N NE1  . TRP A 1 268 ? -36.535 -3.377  -32.348 1 59.54   ? 268 TRP A NE1  1 ? 
ATOM   4085 C CE2  . TRP A 1 268 ? -35.668 -4.441  -32.337 1 55.265  ? 268 TRP A CE2  1 ? 
ATOM   4086 C CE3  . TRP A 1 268 ? -35.785 -6.85   -32.603 1 60.564  ? 268 TRP A CE3  1 ? 
ATOM   4087 C CZ2  . TRP A 1 268 ? -34.287 -4.484  -32.149 1 55.766  ? 268 TRP A CZ2  1 ? 
ATOM   4088 C CZ3  . TRP A 1 268 ? -34.417 -6.888  -32.429 1 58.383  ? 268 TRP A CZ3  1 ? 
ATOM   4089 C CH2  . TRP A 1 268 ? -33.681 -5.722  -32.193 1 56.945  ? 268 TRP A CH2  1 ? 
ATOM   4090 H H    . TRP A 1 268 ? -39.794 -4.837  -30.748 1 52.207  ? 268 TRP A H    1 c 
ATOM   4091 H HA   . TRP A 1 268 ? -40.304 -7.304  -31.982 1 54.956  ? 268 TRP A HA   1 c 
ATOM   4092 H HB2  . TRP A 1 268 ? -38.671 -6.842  -33.523 1 57.69   ? 268 TRP A HB2  1 c 
ATOM   4093 H HB3  . TRP A 1 268 ? -39.656 -5.608  -33.453 1 57.689  ? 268 TRP A HB3  1 c 
ATOM   4094 H HD1  . TRP A 1 268 ? -38.57  -3.276  -32.626 1 57.427  ? 268 TRP A HD1  1 c 
ATOM   4095 H HE1  . TRP A 1 268 ? -36.309 -2.541  -32.237 1 57.813  ? 268 TRP A HE1  1 c 
ATOM   4096 H HE3  . TRP A 1 268 ? -36.274 -7.639  -32.761 1 59.425  ? 268 TRP A HE3  1 c 
ATOM   4097 H HZ2  . TRP A 1 268 ? -33.79  -3.698  -31.997 1 55.997  ? 268 TRP A HZ2  1 c 
ATOM   4098 H HZ3  . TRP A 1 268 ? -33.972 -7.719  -32.447 1 58.513  ? 268 TRP A HZ3  1 c 
ATOM   4099 H HH2  . TRP A 1 268 ? -32.75  -5.782  -32.071 1 57.018  ? 268 TRP A HH2  1 c 
ATOM   4100 N N    . ALA A 1 269 ? -37.927 -6.874  -29.854 1 49.602  ? 269 ALA A N    1 ? 
ATOM   4101 C CA   . ALA A 1 269 ? -36.848 -7.503  -29.096 1 58.41   ? 269 ALA A CA   1 ? 
ATOM   4102 C C    . ALA A 1 269 ? -37.369 -8.514  -28.066 1 59.473  ? 269 ALA A C    1 ? 
ATOM   4103 O O    . ALA A 1 269 ? -36.729 -9.542  -27.825 1 48.37   ? 269 ALA A O    1 ? 
ATOM   4104 C CB   . ALA A 1 269 ? -36.001 -6.443  -28.423 1 63.548  ? 269 ALA A CB   1 ? 
ATOM   4105 H H    . ALA A 1 269 ? -38.152 -6.014  -29.642 1 52.226  ? 269 ALA A H    1 c 
ATOM   4106 H HA   . ALA A 1 269 ? -36.274 -8      -29.742 1 57.565  ? 269 ALA A HA   1 c 
ATOM   4107 H HB1  . ALA A 1 269 ? -35.566 -5.896  -29.099 1 61.942  ? 269 ALA A HB1  1 c 
ATOM   4108 H HB2  . ALA A 1 269 ? -36.564 -5.879  -27.867 1 61.887  ? 269 ALA A HB2  1 c 
ATOM   4109 H HB3  . ALA A 1 269 ? -35.325 -6.867  -27.869 1 61.871  ? 269 ALA A HB3  1 c 
ATOM   4110 N N    . TYR A 1 270 ? -38.53  -8.233  -27.457 1 56.135  ? 270 TYR A N    1 ? 
ATOM   4111 C CA   . TYR A 1 270 ? -39.01  -9.035  -26.346 1 49.573  ? 270 TYR A CA   1 ? 
ATOM   4112 C C    . TYR A 1 270 ? -39.855 -10.21  -26.848 1 48.798  ? 270 TYR A C    1 ? 
ATOM   4113 O O    . TYR A 1 270 ? -40.738 -10.054 -27.685 1 47.966  ? 270 TYR A O    1 ? 
ATOM   4114 C CB   . TYR A 1 270 ? -39.819 -8.227  -25.327 1 46.955  ? 270 TYR A CB   1 ? 
ATOM   4115 C CG   . TYR A 1 270 ? -40.67  -9.136  -24.452 1 45.521  ? 270 TYR A CG   1 ? 
ATOM   4116 C CD1  . TYR A 1 270 ? -40.122 -9.799  -23.36  1 44.529  ? 270 TYR A CD1  1 ? 
ATOM   4117 C CD2  . TYR A 1 270 ? -41.996 -9.396  -24.772 1 45.726  ? 270 TYR A CD2  1 ? 
ATOM   4118 C CE1  . TYR A 1 270 ? -40.886 -10.661 -22.59  1 42.108  ? 270 TYR A CE1  1 ? 
ATOM   4119 C CE2  . TYR A 1 270 ? -42.765 -10.277 -24.025 1 47.538  ? 270 TYR A CE2  1 ? 
ATOM   4120 C CZ   . TYR A 1 270 ? -42.2   -10.919 -22.935 1 42.85   ? 270 TYR A CZ   1 ? 
ATOM   4121 O OH   . TYR A 1 270 ? -42.951 -11.771 -22.189 1 40.769  ? 270 TYR A OH   1 ? 
ATOM   4122 H H    . TYR A 1 270 ? -39.031 -7.522  -27.735 1 55.246  ? 270 TYR A H    1 c 
ATOM   4123 H HA   . TYR A 1 270 ? -38.225 -9.4    -25.87  1 50.096  ? 270 TYR A HA   1 c 
ATOM   4124 H HB2  . TYR A 1 270 ? -39.2   -7.715  -24.761 1 47.22   ? 270 TYR A HB2  1 c 
ATOM   4125 H HB3  . TYR A 1 270 ? -40.403 -7.601  -25.805 1 47.294  ? 270 TYR A HB3  1 c 
ATOM   4126 H HD1  . TYR A 1 270 ? -39.22  -9.646  -23.128 1 44.195  ? 270 TYR A HD1  1 c 
ATOM   4127 H HD2  . TYR A 1 270 ? -42.378 -8.981  -25.528 1 46.04   ? 270 TYR A HD2  1 c 
ATOM   4128 H HE1  . TYR A 1 270 ? -40.5   -11.1   -21.851 1 42.887  ? 270 TYR A HE1  1 c 
ATOM   4129 H HE2  . TYR A 1 270 ? -43.665 -10.436 -24.254 1 45.923  ? 270 TYR A HE2  1 c 
ATOM   4130 N N    . ALA A 1 271 ? -39.605 -11.396 -26.282 1 48.714  ? 271 ALA A N    1 ? 
ATOM   4131 C CA   . ALA A 1 271 ? -40.62  -12.437 -26.205 1 46.412  ? 271 ALA A CA   1 ? 
ATOM   4132 C C    . ALA A 1 271 ? -40.416 -13.197 -24.908 1 43.564  ? 271 ALA A C    1 ? 
ATOM   4133 O O    . ALA A 1 271 ? -39.341 -13.15  -24.326 1 48.037  ? 271 ALA A O    1 ? 
ATOM   4134 C CB   . ALA A 1 271 ? -40.574 -13.361 -27.414 1 47.476  ? 271 ALA A CB   1 ? 
ATOM   4135 H H    . ALA A 1 271 ? -38.773 -11.568 -25.947 1 48.198  ? 271 ALA A H    1 c 
ATOM   4136 H HA   . ALA A 1 271 ? -41.516 -11.999 -26.166 1 46.515  ? 271 ALA A HA   1 c 
ATOM   4137 H HB1  . ALA A 1 271 ? -40.142 -12.906 -28.157 1 47.3    ? 271 ALA A HB1  1 c 
ATOM   4138 H HB2  . ALA A 1 271 ? -40.074 -14.165 -27.196 1 47.259  ? 271 ALA A HB2  1 c 
ATOM   4139 H HB3  . ALA A 1 271 ? -41.478 -13.606 -27.672 1 47.206  ? 271 ALA A HB3  1 c 
ATOM   4140 N N    . HIS A 1 272 ? -41.465 -13.89  -24.479 1 46.252  ? 272 HIS A N    1 ? 
ATOM   4141 C CA   . HIS A 1 272 ? -41.444 -14.685 -23.264 1 49.144  ? 272 HIS A CA   1 ? 
ATOM   4142 C C    . HIS A 1 272 ? -40.213 -15.61  -23.237 1 48.835  ? 272 HIS A C    1 ? 
ATOM   4143 O O    . HIS A 1 272 ? -39.576 -15.71  -22.194 1 44.213  ? 272 HIS A O    1 ? 
ATOM   4144 C CB   . HIS A 1 272 ? -42.81  -15.362 -23.092 1 49.536  ? 272 HIS A CB   1 ? 
ATOM   4145 C CG   . HIS A 1 272 ? -43.02  -16.46  -24.08  1 63.021  ? 272 HIS A CG   1 ? 
ATOM   4146 N ND1  . HIS A 1 272 ? -43.45  -16.265 -25.38  1 64.597  ? 272 HIS A ND1  1 ? 
ATOM   4147 C CD2  . HIS A 1 272 ? -42.799 -17.777 -23.949 1 69.921  ? 272 HIS A CD2  1 ? 
ATOM   4148 C CE1  . HIS A 1 272 ? -43.505 -17.438 -25.999 1 68.438  ? 272 HIS A CE1  1 ? 
ATOM   4149 N NE2  . HIS A 1 272 ? -43.116 -18.369 -25.145 1 71.711  ? 272 HIS A NE2  1 ? 
ATOM   4150 H H    . HIS A 1 272 ? -42.237 -13.86  -24.967 1 46.461  ? 272 HIS A H    1 c 
ATOM   4151 H HA   . HIS A 1 272 ? -41.348 -14.043 -22.517 1 48.556  ? 272 HIS A HA   1 c 
ATOM   4152 H HB2  . HIS A 1 272 ? -42.877 -15.727 -22.187 1 52.35   ? 272 HIS A HB2  1 c 
ATOM   4153 H HB3  . HIS A 1 272 ? -43.516 -14.689 -23.203 1 52.274  ? 272 HIS A HB3  1 c 
ATOM   4154 H HD2  . HIS A 1 272 ? -42.498 -18.221 -23.181 1 68.514  ? 272 HIS A HD2  1 c 
ATOM   4155 H HE1  . HIS A 1 272 ? -43.78  -17.58  -26.888 1 68.202  ? 272 HIS A HE1  1 c 
ATOM   4156 N N    . ASN A 1 273 ? -39.811 -16.176 -24.389 1 48.399  ? 273 ASN A N    1 ? 
ATOM   4157 C CA   . ASN A 1 273 ? -38.825 -17.249 -24.448 1 51.956  ? 273 ASN A CA   1 ? 
ATOM   4158 C C    . ASN A 1 273 ? -37.58  -16.854 -25.244 1 53.31   ? 273 ASN A C    1 ? 
ATOM   4159 O O    . ASN A 1 273 ? -36.876 -17.738 -25.748 1 58.366  ? 273 ASN A O    1 ? 
ATOM   4160 C CB   . ASN A 1 273 ? -39.451 -18.491 -25.072 1 55.853  ? 273 ASN A CB   1 ? 
ATOM   4161 C CG   . ASN A 1 273 ? -39.687 -18.307 -26.557 1 63.677  ? 273 ASN A CG   1 ? 
ATOM   4162 O OD1  . ASN A 1 273 ? -40.023 -17.203 -27.006 1 60.586  ? 273 ASN A OD1  1 ? 
ATOM   4163 N ND2  . ASN A 1 273 ? -39.45  -19.347 -27.342 1 65.18   ? 273 ASN A ND2  1 ? 
ATOM   4164 H H    . ASN A 1 273 ? -40.183 -15.894 -25.174 1 49.297  ? 273 ASN A H    1 c 
ATOM   4165 H HA   . ASN A 1 273 ? -38.55  -17.484 -23.533 1 52.116  ? 273 ASN A HA   1 c 
ATOM   4166 H HB2  . ASN A 1 273 ? -38.86  -19.258 -24.932 1 56.689  ? 273 ASN A HB2  1 c 
ATOM   4167 H HB3  . ASN A 1 273 ? -40.301 -18.681 -24.632 1 56.691  ? 273 ASN A HB3  1 c 
ATOM   4168 H HD21 . ASN A 1 273 ? -39.124 -19.221 -28.157 1 64.698  ? 273 ASN A HD21 1 c 
ATOM   4169 H HD22 . ASN A 1 273 ? -39.618 -20.168 -27.052 1 64.649  ? 273 ASN A HD22 1 c 
ATOM   4170 N N    . LYS A 1 274 ? -37.323 -15.541 -25.389 1 53.485  ? 274 LYS A N    1 ? 
ATOM   4171 C CA   . LYS A 1 274 ? -36.145 -15.062 -26.098 1 49.956  ? 274 LYS A CA   1 ? 
ATOM   4172 C C    . LYS A 1 274 ? -35.103 -14.568 -25.095 1 54.611  ? 274 LYS A C    1 ? 
ATOM   4173 O O    . LYS A 1 274 ? -35.183 -13.446 -24.572 1 45.175  ? 274 LYS A O    1 ? 
ATOM   4174 C CB   . LYS A 1 274 ? -36.483 -13.978 -27.117 1 55.033  ? 274 LYS A CB   1 ? 
ATOM   4175 C CG   . LYS A 1 274 ? -37.191 -14.5   -28.349 1 62.992  ? 274 LYS A CG   1 ? 
ATOM   4176 C CD   . LYS A 1 274 ? -37.408 -13.409 -29.393 1 66.584  ? 274 LYS A CD   1 ? 
ATOM   4177 C CE   . LYS A 1 274 ? -38.102 -13.925 -30.61  1 70.663  ? 274 LYS A CE   1 ? 
ATOM   4178 N NZ   . LYS A 1 274 ? -38.188 -12.869 -31.619 1 76.282  ? 274 LYS A NZ   1 ? 
ATOM   4179 H H    . LYS A 1 274 ? -37.892 -14.925 -25.026 1 52.587  ? 274 LYS A H    1 c 
ATOM   4180 H HA   . LYS A 1 274 ? -35.767 -15.808 -26.608 1 52.519  ? 274 LYS A HA   1 c 
ATOM   4181 H HB2  . LYS A 1 274 ? -37.055 -13.305 -26.689 1 55.538  ? 274 LYS A HB2  1 c 
ATOM   4182 H HB3  . LYS A 1 274 ? -35.655 -13.533 -27.398 1 55.536  ? 274 LYS A HB3  1 c 
ATOM   4183 H HG2  . LYS A 1 274 ? -36.654 -15.222 -28.742 1 61.749  ? 274 LYS A HG2  1 c 
ATOM   4184 H HG3  . LYS A 1 274 ? -38.059 -14.873 -28.084 1 61.709  ? 274 LYS A HG3  1 c 
ATOM   4185 H HD2  . LYS A 1 274 ? -37.943 -12.687 -28.998 1 66.525  ? 274 LYS A HD2  1 c 
ATOM   4186 H HD3  . LYS A 1 274 ? -36.537 -13.037 -29.653 1 66.686  ? 274 LYS A HD3  1 c 
ATOM   4187 H HE2  . LYS A 1 274 ? -37.61  -14.682 -30.977 1 70.981  ? 274 LYS A HE2  1 c 
ATOM   4188 H HE3  . LYS A 1 274 ? -39     -14.223 -30.378 1 70.981  ? 274 LYS A HE3  1 c 
ATOM   4189 H HZ1  . LYS A 1 274 ? -37.355 -12.602 -31.857 1 74.393  ? 274 LYS A HZ1  1 c 
ATOM   4190 H HZ2  . LYS A 1 274 ? -38.643 -12.16  -31.284 1 74.434  ? 274 LYS A HZ2  1 c 
ATOM   4191 H HZ3  . LYS A 1 274 ? -38.621 -13.18  -32.351 1 74.471  ? 274 LYS A HZ3  1 c 
ATOM   4192 N N    . PHE A 1 275 ? -34.097 -15.423 -24.869 1 52.236  ? 275 PHE A N    1 ? 
ATOM   4193 C CA   . PHE A 1 275 ? -33.08  -15.201 -23.856 1 48.942  ? 275 PHE A CA   1 ? 
ATOM   4194 C C    . PHE A 1 275 ? -31.842 -14.568 -24.479 1 44.125  ? 275 PHE A C    1 ? 
ATOM   4195 O O    . PHE A 1 275 ? -31.666 -14.571 -25.69  1 51.826  ? 275 PHE A O    1 ? 
ATOM   4196 C CB   . PHE A 1 275 ? -32.767 -16.541 -23.192 1 42.709  ? 275 PHE A CB   1 ? 
ATOM   4197 C CG   . PHE A 1 275 ? -33.9   -17.115 -22.354 1 40.108  ? 275 PHE A CG   1 ? 
ATOM   4198 C CD1  . PHE A 1 275 ? -34.937 -17.826 -22.937 1 43.211  ? 275 PHE A CD1  1 ? 
ATOM   4199 C CD2  . PHE A 1 275 ? -33.873 -17.028 -20.972 1 41.3    ? 275 PHE A CD2  1 ? 
ATOM   4200 C CE1  . PHE A 1 275 ? -35.954 -18.377 -22.161 1 43.986  ? 275 PHE A CE1  1 ? 
ATOM   4201 C CE2  . PHE A 1 275 ? -34.884 -17.594 -20.2   1 42.066  ? 275 PHE A CE2  1 ? 
ATOM   4202 C CZ   . PHE A 1 275 ? -35.926 -18.256 -20.795 1 42.102  ? 275 PHE A CZ   1 ? 
ATOM   4203 H H    . PHE A 1 275 ? -34.039 -16.18  -25.377 1 51.868  ? 275 PHE A H    1 c 
ATOM   4204 H HA   . PHE A 1 275 ? -33.441 -14.585 -23.167 1 47.432  ? 275 PHE A HA   1 c 
ATOM   4205 H HB2  . PHE A 1 275 ? -32.531 -17.189 -23.892 1 43.476  ? 275 PHE A HB2  1 c 
ATOM   4206 H HB3  . PHE A 1 275 ? -31.977 -16.425 -22.618 1 43.417  ? 275 PHE A HB3  1 c 
ATOM   4207 H HD1  . PHE A 1 275 ? -34.971 -17.91  -23.876 1 42.713  ? 275 PHE A HD1  1 c 
ATOM   4208 H HD2  . PHE A 1 275 ? -33.165 -16.569 -20.55  1 41.255  ? 275 PHE A HD2  1 c 
ATOM   4209 H HE1  . PHE A 1 275 ? -36.664 -18.838 -22.578 1 43.314  ? 275 PHE A HE1  1 c 
ATOM   4210 H HE2  . PHE A 1 275 ? -34.862 -17.501 -19.26  1 41.909  ? 275 PHE A HE2  1 c 
ATOM   4211 H HZ   . PHE A 1 275 ? -36.611 -18.634 -20.269 1 42.596  ? 275 PHE A HZ   1 c 
ATOM   4212 N N    . PHE A 1 276 ? -30.972 -14.043 -23.619 1 43.889  ? 276 PHE A N    1 ? 
ATOM   4213 C CA   . PHE A 1 276 ? -29.747 -13.409 -24.064 1 43.392  ? 276 PHE A CA   1 ? 
ATOM   4214 C C    . PHE A 1 276 ? -28.657 -14.476 -24.083 1 50.103  ? 276 PHE A C    1 ? 
ATOM   4215 O O    . PHE A 1 276 ? -28.083 -14.763 -23.031 1 47.124  ? 276 PHE A O    1 ? 
ATOM   4216 C CB   . PHE A 1 276 ? -29.495 -12.24  -23.105 1 44.23   ? 276 PHE A CB   1 ? 
ATOM   4217 C CG   . PHE A 1 276 ? -28.327 -11.316 -23.445 1 56.478  ? 276 PHE A CG   1 ? 
ATOM   4218 C CD1  . PHE A 1 276 ? -27.113 -11.798 -23.943 1 59.856  ? 276 PHE A CD1  1 ? 
ATOM   4219 C CD2  . PHE A 1 276 ? -28.448 -9.942  -23.264 1 64.429  ? 276 PHE A CD2  1 ? 
ATOM   4220 C CE1  . PHE A 1 276 ? -26.066 -10.936 -24.239 1 62.625  ? 276 PHE A CE1  1 ? 
ATOM   4221 C CE2  . PHE A 1 276 ? -27.395 -9.083  -23.567 1 70.369  ? 276 PHE A CE2  1 ? 
ATOM   4222 C CZ   . PHE A 1 276 ? -26.205 -9.583  -24.042 1 65.466  ? 276 PHE A CZ   1 ? 
ATOM   4223 H H    . PHE A 1 276 ? -31.146 -14.086 -22.723 1 43.914  ? 276 PHE A H    1 c 
ATOM   4224 H HA   . PHE A 1 276 ? -29.868 -13.052 -24.977 1 44.931  ? 276 PHE A HA   1 c 
ATOM   4225 H HB2  . PHE A 1 276 ? -30.316 -11.7   -23.063 1 46.735  ? 276 PHE A HB2  1 c 
ATOM   4226 H HB3  . PHE A 1 276 ? -29.348 -12.608 -22.207 1 46.616  ? 276 PHE A HB3  1 c 
ATOM   4227 H HD1  . PHE A 1 276 ? -26.993 -12.719 -24.075 1 59.455  ? 276 PHE A HD1  1 c 
ATOM   4228 H HD2  . PHE A 1 276 ? -29.256 -9.587  -22.929 1 63.403  ? 276 PHE A HD2  1 c 
ATOM   4229 H HE1  . PHE A 1 276 ? -25.253 -11.282 -24.57  1 62.598  ? 276 PHE A HE1  1 c 
ATOM   4230 H HE2  . PHE A 1 276 ? -27.492 -8.16   -23.43  1 67.621  ? 276 PHE A HE2  1 c 
ATOM   4231 H HZ   . PHE A 1 276 ? -25.495 -8.998  -24.251 1 65.752  ? 276 PHE A HZ   1 c 
ATOM   4232 N N    . TYR A 1 277 ? -28.39  -15.042 -25.275 1 49.027  ? 277 TYR A N    1 ? 
ATOM   4233 C CA   . TYR A 1 277 ? -27.249 -15.921 -25.506 1 47.479  ? 277 TYR A CA   1 ? 
ATOM   4234 C C    . TYR A 1 277 ? -26.116 -15.089 -26.096 1 50.326  ? 277 TYR A C    1 ? 
ATOM   4235 O O    . TYR A 1 277 ? -26.366 -14.036 -26.68  1 59.448  ? 277 TYR A O    1 ? 
ATOM   4236 C CB   . TYR A 1 277 ? -27.62  -17.091 -26.42  1 46.934  ? 277 TYR A CB   1 ? 
ATOM   4237 C CG   . TYR A 1 277 ? -28.445 -18.209 -25.792 1 48.213  ? 277 TYR A CG   1 ? 
ATOM   4238 C CD1  . TYR A 1 277 ? -29.135 -18.041 -24.595 1 51.266  ? 277 TYR A CD1  1 ? 
ATOM   4239 C CD2  . TYR A 1 277 ? -28.533 -19.451 -26.409 1 52.017  ? 277 TYR A CD2  1 ? 
ATOM   4240 C CE1  . TYR A 1 277 ? -29.873 -19.07  -24.029 1 50.19   ? 277 TYR A CE1  1 ? 
ATOM   4241 C CE2  . TYR A 1 277 ? -29.259 -20.495 -25.847 1 55.747  ? 277 TYR A CE2  1 ? 
ATOM   4242 C CZ   . TYR A 1 277 ? -29.939 -20.298 -24.66  1 50.22   ? 277 TYR A CZ   1 ? 
ATOM   4243 O OH   . TYR A 1 277 ? -30.67  -21.294 -24.1   1 45.13   ? 277 TYR A OH   1 ? 
ATOM   4244 H H    . TYR A 1 277 ? -28.952 -14.874 -25.976 1 48.84   ? 277 TYR A H    1 c 
ATOM   4245 H HA   . TYR A 1 277 ? -26.948 -16.288 -24.634 1 48.32   ? 277 TYR A HA   1 c 
ATOM   4246 H HB2  . TYR A 1 277 ? -28.116 -16.734 -27.189 1 47.408  ? 277 TYR A HB2  1 c 
ATOM   4247 H HB3  . TYR A 1 277 ? -26.788 -17.481 -26.77  1 47.375  ? 277 TYR A HB3  1 c 
ATOM   4248 H HD1  . TYR A 1 277 ? -29.099 -17.214 -24.148 1 50.255  ? 277 TYR A HD1  1 c 
ATOM   4249 H HD2  . TYR A 1 277 ? -28.069 -19.597 -27.218 1 51.877  ? 277 TYR A HD2  1 c 
ATOM   4250 H HE1  . TYR A 1 277 ? -30.332 -18.933 -23.218 1 50.425  ? 277 TYR A HE1  1 c 
ATOM   4251 H HE2  . TYR A 1 277 ? -29.307 -21.327 -26.285 1 53.402  ? 277 TYR A HE2  1 c 
ATOM   4252 N N    . ILE A 1 278 ? -24.879 -15.573 -25.952 1 51.762  ? 278 ILE A N    1 ? 
ATOM   4253 C CA   . ILE A 1 278 ? -23.696 -14.885 -26.46  1 62.144  ? 278 ILE A CA   1 ? 
ATOM   4254 C C    . ILE A 1 278 ? -23.853 -14.6   -27.961 1 63.644  ? 278 ILE A C    1 ? 
ATOM   4255 O O    . ILE A 1 278 ? -23.438 -13.542 -28.441 1 61.043  ? 278 ILE A O    1 ? 
ATOM   4256 C CB   . ILE A 1 278 ? -22.419 -15.706 -26.158 1 68.482  ? 278 ILE A CB   1 ? 
ATOM   4257 C CG1  . ILE A 1 278 ? -22.241 -15.913 -24.652 1 70.756  ? 278 ILE A CG1  1 ? 
ATOM   4258 C CG2  . ILE A 1 278 ? -21.158 -15.085 -26.78  1 69.55   ? 278 ILE A CG2  1 ? 
ATOM   4259 C CD1  . ILE A 1 278 ? -21.109 -16.849 -24.292 1 74.209  ? 278 ILE A CD1  1 ? 
ATOM   4260 H H    . ILE A 1 278 ? -24.776 -16.389 -25.553 1 53.801  ? 278 ILE A H    1 c 
ATOM   4261 H HA   . ILE A 1 278 ? -23.622 -14.03  -25.994 1 61.297  ? 278 ILE A HA   1 c 
ATOM   4262 H HB   . ILE A 1 278 ? -22.539 -16.59  -26.56  1 67.872  ? 278 ILE A HB   1 c 
ATOM   4263 H HG12 . ILE A 1 278 ? -22.074 -15.043 -24.235 1 70.895  ? 278 ILE A HG12 1 c 
ATOM   4264 H HG13 . ILE A 1 278 ? -23.069 -16.267 -24.278 1 70.427  ? 278 ILE A HG13 1 c 
ATOM   4265 H HG21 . ILE A 1 278 ? -20.383 -15.631 -26.571 1 69.282  ? 278 ILE A HG21 1 c 
ATOM   4266 H HG22 . ILE A 1 278 ? -21.026 -14.191 -26.424 1 69.242  ? 278 ILE A HG22 1 c 
ATOM   4267 H HG23 . ILE A 1 278 ? -21.256 -15.035 -27.745 1 69.217  ? 278 ILE A HG23 1 c 
ATOM   4268 H HD11 . ILE A 1 278 ? -21.144 -17.636 -24.869 1 73.082  ? 278 ILE A HD11 1 c 
ATOM   4269 H HD12 . ILE A 1 278 ? -21.2   -17.126 -23.364 1 72.85   ? 278 ILE A HD12 1 c 
ATOM   4270 H HD13 . ILE A 1 278 ? -20.253 -16.4   -24.412 1 73.037  ? 278 ILE A HD13 1 c 
ATOM   4271 N N    . SER A 1 279 ? -24.429 -15.564 -28.694 1 67.687  ? 279 SER A N    1 ? 
ATOM   4272 C CA   . SER A 1 279 ? -24.557 -15.483 -30.142 1 87.883  ? 279 SER A CA   1 ? 
ATOM   4273 C C    . SER A 1 279 ? -25.781 -14.651 -30.537 1 86.02   ? 279 SER A C    1 ? 
ATOM   4274 O O    . SER A 1 279 ? -25.668 -13.772 -31.385 1 94.524  ? 279 SER A O    1 ? 
ATOM   4275 C CB   . SER A 1 279 ? -24.599 -16.872 -30.758 1 87.136  ? 279 SER A CB   1 ? 
ATOM   4276 O OG   . SER A 1 279 ? -25.654 -17.653 -30.207 1 87.255  ? 279 SER A OG   1 ? 
ATOM   4277 H H    . SER A 1 279 ? -24.739 -16.316 -28.277 1 70.538  ? 279 SER A H    1 c 
ATOM   4278 H HA   . SER A 1 279 ? -23.753 -15.022 -30.494 1 82.856  ? 279 SER A HA   1 c 
ATOM   4279 H HB2  . SER A 1 279 ? -24.724 -16.793 -31.722 1 87.332  ? 279 SER A HB2  1 c 
ATOM   4280 H HB3  . SER A 1 279 ? -23.747 -17.321 -30.598 1 87.332  ? 279 SER A HB3  1 c 
ATOM   4281 N N    . ASP A 1 280 ? -26.939 -14.964 -29.939 1 76.498  ? 280 ASP A N    1 ? 
ATOM   4282 C CA   . ASP A 1 280 ? -28.204 -14.302 -30.232 1 71.6    ? 280 ASP A CA   1 ? 
ATOM   4283 C C    . ASP A 1 280 ? -28.732 -13.681 -28.936 1 61.487  ? 280 ASP A C    1 ? 
ATOM   4284 O O    . ASP A 1 280 ? -29.132 -14.405 -28.026 1 57.724  ? 280 ASP A O    1 ? 
ATOM   4285 C CB   . ASP A 1 280 ? -29.2   -15.279 -30.86  1 70.381  ? 280 ASP A CB   1 ? 
ATOM   4286 C CG   . ASP A 1 280 ? -30.544 -14.698 -31.294 1 80.56   ? 280 ASP A CG   1 ? 
ATOM   4287 O OD1  . ASP A 1 280 ? -30.718 -13.456 -31.214 1 92.8    ? 280 ASP A OD1  1 ? 
ATOM   4288 O OD2  . ASP A 1 280 ? -31.408 -15.487 -31.737 1 86.543  ? 280 ASP A OD2  1 ? 
ATOM   4289 H H    . ASP A 1 280 ? -26.943 -15.635 -29.319 1 77.493  ? 280 ASP A H    1 c 
ATOM   4290 H HA   . ASP A 1 280 ? -28.044 -13.587 -30.886 1 70.448  ? 280 ASP A HA   1 c 
ATOM   4291 H HB2  . ASP A 1 280 ? -28.779 -15.67  -31.654 1 72.865  ? 280 ASP A HB2  1 c 
ATOM   4292 H HB3  . ASP A 1 280 ? -29.367 -16.007 -30.23  1 72.765  ? 280 ASP A HB3  1 c 
ATOM   4293 N N    . TYR A 1 281 ? -28.799 -12.342 -28.892 1 58.266  ? 281 TYR A N    1 ? 
ATOM   4294 C CA   . TYR A 1 281 ? -29.296 -11.619 -27.731 1 57.968  ? 281 TYR A CA   1 ? 
ATOM   4295 C C    . TYR A 1 281 ? -30.792 -11.866 -27.523 1 53.442  ? 281 TYR A C    1 ? 
ATOM   4296 O O    . TYR A 1 281 ? -31.291 -11.68  -26.411 1 53.05   ? 281 TYR A O    1 ? 
ATOM   4297 C CB   . TYR A 1 281 ? -29.02  -10.119 -27.877 1 64.18   ? 281 TYR A CB   1 ? 
ATOM   4298 C CG   . TYR A 1 281 ? -27.575 -9.706  -28.127 1 70.832  ? 281 TYR A CG   1 ? 
ATOM   4299 C CD1  . TYR A 1 281 ? -26.499 -10.457 -27.659 1 78.021  ? 281 TYR A CD1  1 ? 
ATOM   4300 C CD2  . TYR A 1 281 ? -27.292 -8.533  -28.822 1 83.699  ? 281 TYR A CD2  1 ? 
ATOM   4301 C CE1  . TYR A 1 281 ? -25.188 -10.055 -27.88  1 82.014  ? 281 TYR A CE1  1 ? 
ATOM   4302 C CE2  . TYR A 1 281 ? -25.988 -8.126  -29.059 1 84.751  ? 281 TYR A CE2  1 ? 
ATOM   4303 C CZ   . TYR A 1 281 ? -24.935 -8.885  -28.579 1 84.903  ? 281 TYR A CZ   1 ? 
ATOM   4304 O OH   . TYR A 1 281 ? -23.663 -8.47   -28.819 1 90.148  ? 281 TYR A OH   1 ? 
ATOM   4305 H H    . TYR A 1 281 ? -28.534 -11.862 -29.624 1 59.213  ? 281 TYR A H    1 c 
ATOM   4306 H HA   . TYR A 1 281 ? -28.814 -11.95  -26.929 1 58.424  ? 281 TYR A HA   1 c 
ATOM   4307 H HB2  . TYR A 1 281 ? -29.571 -9.78   -28.617 1 64.138  ? 281 TYR A HB2  1 c 
ATOM   4308 H HB3  . TYR A 1 281 ? -29.333 -9.672  -27.059 1 64.138  ? 281 TYR A HB3  1 c 
ATOM   4309 H HD1  . TYR A 1 281 ? -26.658 -11.25  -27.175 1 76.968  ? 281 TYR A HD1  1 c 
ATOM   4310 H HD2  . TYR A 1 281 ? -28.004 -8.007  -29.149 1 80.693  ? 281 TYR A HD2  1 c 
ATOM   4311 H HE1  . TYR A 1 281 ? -24.472 -10.576 -27.559 1 81.676  ? 281 TYR A HE1  1 c 
ATOM   4312 H HE2  . TYR A 1 281 ? -25.818 -7.33   -29.533 1 84.384  ? 281 TYR A HE2  1 c 
ATOM   4313 N N    . TYR A 1 282 ? -31.502 -12.274 -28.587 1 50.659  ? 282 TYR A N    1 ? 
ATOM   4314 C CA   . TYR A 1 282 ? -32.922 -12.588 -28.511 1 57.213  ? 282 TYR A CA   1 ? 
ATOM   4315 C C    . TYR A 1 282 ? -33.139 -14.02  -29.012 1 62.132  ? 282 TYR A C    1 ? 
ATOM   4316 O O    . TYR A 1 282 ? -33.873 -14.234 -29.976 1 69.198  ? 282 TYR A O    1 ? 
ATOM   4317 C CB   . TYR A 1 282 ? -33.685 -11.504 -29.298 1 54.176  ? 282 TYR A CB   1 ? 
ATOM   4318 C CG   . TYR A 1 282 ? -33.097 -10.103 -29.156 1 49.242  ? 282 TYR A CG   1 ? 
ATOM   4319 C CD1  . TYR A 1 282 ? -33.309 -9.328  -28.014 1 50.839  ? 282 TYR A CD1  1 ? 
ATOM   4320 C CD2  . TYR A 1 282 ? -32.275 -9.572  -30.147 1 54.167  ? 282 TYR A CD2  1 ? 
ATOM   4321 C CE1  . TYR A 1 282 ? -32.719 -8.079  -27.866 1 47.13   ? 282 TYR A CE1  1 ? 
ATOM   4322 C CE2  . TYR A 1 282 ? -31.705 -8.308  -30.027 1 50.759  ? 282 TYR A CE2  1 ? 
ATOM   4323 C CZ   . TYR A 1 282 ? -31.933 -7.56   -28.884 1 50.77   ? 282 TYR A CZ   1 ? 
ATOM   4324 O OH   . TYR A 1 282 ? -31.365 -6.328  -28.75  1 54.856  ? 282 TYR A OH   1 ? 
ATOM   4325 H H    . TYR A 1 282 ? -31.097 -12.325 -29.405 1 52.862  ? 282 TYR A H    1 c 
ATOM   4326 H HA   . TYR A 1 282 ? -33.213 -12.544 -27.562 1 56.135  ? 282 TYR A HA   1 c 
ATOM   4327 H HB2  . TYR A 1 282 ? -33.688 -11.748 -30.249 1 53.776  ? 282 TYR A HB2  1 c 
ATOM   4328 H HB3  . TYR A 1 282 ? -34.618 -11.49  -28.987 1 53.687  ? 282 TYR A HB3  1 c 
ATOM   4329 H HD1  . TYR A 1 282 ? -33.838 -9.673  -27.313 1 49.652  ? 282 TYR A HD1  1 c 
ATOM   4330 H HD2  . TYR A 1 282 ? -32.115 -10.075 -30.93  1 52.172  ? 282 TYR A HD2  1 c 
ATOM   4331 H HE1  . TYR A 1 282 ? -32.886 -7.567  -27.094 1 48.89   ? 282 TYR A HE1  1 c 
ATOM   4332 H HE2  . TYR A 1 282 ? -31.159 -7.966  -30.715 1 51.518  ? 282 TYR A HE2  1 c 
ATOM   4333 N N    . HIS A 1 283 ? -32.528 -14.995 -28.323 1 60.747  ? 283 HIS A N    1 ? 
ATOM   4334 C CA   . HIS A 1 283 ? -32.537 -16.389 -28.75  1 59.807  ? 283 HIS A CA   1 ? 
ATOM   4335 C C    . HIS A 1 283 ? -33.808 -17.086 -28.274 1 56.509  ? 283 HIS A C    1 ? 
ATOM   4336 O O    . HIS A 1 283 ? -34.023 -17.265 -27.076 1 56.325  ? 283 HIS A O    1 ? 
ATOM   4337 C CB   . HIS A 1 283 ? -31.298 -17.149 -28.247 1 57.556  ? 283 HIS A CB   1 ? 
ATOM   4338 C CG   . HIS A 1 283 ? -31.149 -18.493 -28.877 1 63.852  ? 283 HIS A CG   1 ? 
ATOM   4339 N ND1  . HIS A 1 283 ? -31.679 -19.64  -28.322 1 69.866  ? 283 HIS A ND1  1 ? 
ATOM   4340 C CD2  . HIS A 1 283 ? -30.546 -18.875 -30.018 1 66.914  ? 283 HIS A CD2  1 ? 
ATOM   4341 C CE1  . HIS A 1 283 ? -31.391 -20.679 -29.105 1 74.206  ? 283 HIS A CE1  1 ? 
ATOM   4342 N NE2  . HIS A 1 283 ? -30.715 -20.234 -30.145 1 69.12   ? 283 HIS A NE2  1 ? 
ATOM   4343 H H    . HIS A 1 283 ? -32.088 -14.78  -27.551 1 60.813  ? 283 HIS A H    1 c 
ATOM   4344 H HA   . HIS A 1 283 ? -32.52  -16.411 -29.734 1 59.18   ? 283 HIS A HA   1 c 
ATOM   4345 H HB2  . HIS A 1 283 ? -30.5   -16.615 -28.435 1 59.55   ? 283 HIS A HB2  1 c 
ATOM   4346 H HB3  . HIS A 1 283 ? -31.366 -17.257 -27.274 1 59.457  ? 283 HIS A HB3  1 c 
ATOM   4347 H HD2  . HIS A 1 283 ? -30.098 -18.321 -30.627 1 66.693  ? 283 HIS A HD2  1 c 
ATOM   4348 H HE1  . HIS A 1 283 ? -31.64  -21.574 -28.948 1 71.868  ? 283 HIS A HE1  1 c 
ATOM   4349 N N    . ALA A 1 284 ? -34.621 -17.531 -29.232 1 59.341  ? 284 ALA A N    1 ? 
ATOM   4350 C CA   . ALA A 1 284 ? -35.821 -18.285 -28.926 1 64.181  ? 284 ALA A CA   1 ? 
ATOM   4351 C C    . ALA A 1 284 ? -35.399 -19.653 -28.407 1 57.477  ? 284 ALA A C    1 ? 
ATOM   4352 O O    . ALA A 1 284 ? -34.495 -20.253 -28.972 1 61.362  ? 284 ALA A O    1 ? 
ATOM   4353 C CB   . ALA A 1 284 ? -36.692 -18.404 -30.161 1 64.278  ? 284 ALA A CB   1 ? 
ATOM   4354 H H    . ALA A 1 284 ? -34.424 -17.359 -30.108 1 59.732  ? 284 ALA A H    1 c 
ATOM   4355 H HA   . ALA A 1 284 ? -36.323 -17.808 -28.214 1 61.858  ? 284 ALA A HA   1 c 
ATOM   4356 H HB1  . ALA A 1 284 ? -36.932 -17.517 -30.478 1 64.25   ? 284 ALA A HB1  1 c 
ATOM   4357 H HB2  . ALA A 1 284 ? -36.206 -18.873 -30.86  1 64.25   ? 284 ALA A HB2  1 c 
ATOM   4358 H HB3  . ALA A 1 284 ? -37.5   -18.897 -29.945 1 64.25   ? 284 ALA A HB3  1 c 
ATOM   4359 N N    . VAL A 1 285 ? -36.041 -20.117 -27.336 1 59.233  ? 285 VAL A N    1 ? 
ATOM   4360 C CA   . VAL A 1 285 ? -35.658 -21.358 -26.69  1 64.793  ? 285 VAL A CA   1 ? 
ATOM   4361 C C    . VAL A 1 285 ? -36.9   -22.226 -26.614 1 66.73   ? 285 VAL A C    1 ? 
ATOM   4362 O O    . VAL A 1 285 ? -37.975 -21.713 -26.309 1 63.783  ? 285 VAL A O    1 ? 
ATOM   4363 C CB   . VAL A 1 285 ? -35.032 -21.101 -25.305 1 65.755  ? 285 VAL A CB   1 ? 
ATOM   4364 C CG1  . VAL A 1 285 ? -35.04  -22.338 -24.419 1 67.549  ? 285 VAL A CG1  1 ? 
ATOM   4365 C CG2  . VAL A 1 285 ? -33.615 -20.556 -25.435 1 62.661  ? 285 VAL A CG2  1 ? 
ATOM   4366 H H    . VAL A 1 285 ? -36.746 -19.646 -26.994 1 60.127  ? 285 VAL A H    1 c 
ATOM   4367 H HA   . VAL A 1 285 ? -34.996 -21.813 -27.245 1 64.228  ? 285 VAL A HA   1 c 
ATOM   4368 H HB   . VAL A 1 285 ? -35.58  -20.411 -24.863 1 65.317  ? 285 VAL A HB   1 c 
ATOM   4369 H HG11 . VAL A 1 285 ? -34.802 -23.118 -24.945 1 67.008  ? 285 VAL A HG11 1 c 
ATOM   4370 H HG12 . VAL A 1 285 ? -35.925 -22.458 -24.037 1 66.98   ? 285 VAL A HG12 1 c 
ATOM   4371 H HG13 . VAL A 1 285 ? -34.395 -22.227 -23.701 1 66.874  ? 285 VAL A HG13 1 c 
ATOM   4372 H HG21 . VAL A 1 285 ? -33.29  -20.281 -24.561 1 63.579  ? 285 VAL A HG21 1 c 
ATOM   4373 H HG22 . VAL A 1 285 ? -33.615 -19.79  -26.035 1 63.562  ? 285 VAL A HG22 1 c 
ATOM   4374 H HG23 . VAL A 1 285 ? -33.032 -21.246 -25.794 1 63.562  ? 285 VAL A HG23 1 c 
ATOM   4375 N N    . GLU A 1 286 ? -36.713 -23.537 -26.856 1 71.692  ? 286 GLU A N    1 ? 
ATOM   4376 C CA   . GLU A 1 286 ? -37.819 -24.454 -27.107 1 82.289  ? 286 GLU A CA   1 ? 
ATOM   4377 C C    . GLU A 1 286 ? -37.951 -25.485 -25.988 1 76.331  ? 286 GLU A C    1 ? 
ATOM   4378 O O    . GLU A 1 286 ? -38.522 -26.555 -26.188 1 81.112  ? 286 GLU A O    1 ? 
ATOM   4379 C CB   . GLU A 1 286 ? -37.647 -25.116 -28.482 1 89.908  ? 286 GLU A CB   1 ? 
ATOM   4380 C CG   . GLU A 1 286 ? -37.944 -24.211 -29.679 1 94.396  ? 286 GLU A CG   1 ? 
ATOM   4381 C CD   . GLU A 1 286 ? -39.134 -23.27  -29.523 1 92.752  ? 286 GLU A CD   1 ? 
ATOM   4382 O OE1  . GLU A 1 286 ? -40.139 -23.664 -28.884 1 86.053  ? 286 GLU A OE1  1 ? 
ATOM   4383 O OE2  . GLU A 1 286 ? -39.042 -22.132 -30.03  1 91.085  ? 286 GLU A OE2  1 ? 
ATOM   4384 H H    . GLU A 1 286 ? -35.863 -23.872 -26.866 1 72.53   ? 286 GLU A H    1 c 
ATOM   4385 H HA   . GLU A 1 286 ? -38.652 -23.933 -27.106 1 80.175  ? 286 GLU A HA   1 c 
ATOM   4386 H HB2  . GLU A 1 286 ? -36.728 -25.445 -28.558 1 89.083  ? 286 GLU A HB2  1 c 
ATOM   4387 H HB3  . GLU A 1 286 ? -38.245 -25.889 -28.543 1 88.999  ? 286 GLU A HB3  1 c 
ATOM   4388 H HG2  . GLU A 1 286 ? -37.148 -23.67  -29.867 1 92.972  ? 286 GLU A HG2  1 c 
ATOM   4389 H HG3  . GLU A 1 286 ? -38.101 -24.774 -30.466 1 92.981  ? 286 GLU A HG3  1 c 
ATOM   4390 N N    . THR A 1 287 ? -37.494 -25.12  -24.788 1 70.184  ? 287 THR A N    1 ? 
ATOM   4391 C CA   . THR A 1 287 ? -37.383 -26.037 -23.668 1 60.028  ? 287 THR A CA   1 ? 
ATOM   4392 C C    . THR A 1 287 ? -38.692 -26.003 -22.895 1 57.207  ? 287 THR A C    1 ? 
ATOM   4393 O O    . THR A 1 287 ? -39.591 -25.255 -23.259 1 64.749  ? 287 THR A O    1 ? 
ATOM   4394 C CB   . THR A 1 287 ? -36.17  -25.628 -22.834 1 67.153  ? 287 THR A CB   1 ? 
ATOM   4395 O OG1  . THR A 1 287 ? -36.395 -24.313 -22.329 1 63.485  ? 287 THR A OG1  1 ? 
ATOM   4396 C CG2  . THR A 1 287 ? -34.883 -25.654 -23.65  1 63.969  ? 287 THR A CG2  1 ? 
ATOM   4397 H H    . THR A 1 287 ? -37.271 -24.246 -24.646 1 69.147  ? 287 THR A H    1 c 
ATOM   4398 H HA   . THR A 1 287 ? -37.237 -26.94  -24.011 1 62.772  ? 287 THR A HA   1 c 
ATOM   4399 H HB   . THR A 1 287 ? -36.075 -26.247 -22.073 1 64.512  ? 287 THR A HB   1 c 
ATOM   4400 H HG21 . THR A 1 287 ? -34.237 -25.045 -23.255 1 64.89   ? 287 THR A HG21 1 c 
ATOM   4401 H HG22 . THR A 1 287 ? -35.063 -25.383 -24.564 1 64.909  ? 287 THR A HG22 1 c 
ATOM   4402 H HG23 . THR A 1 287 ? -34.517 -26.554 -23.649 1 64.912  ? 287 THR A HG23 1 c 
ATOM   4403 N N    . SER A 1 288 ? -38.803 -26.854 -21.871 1 58.643  ? 288 SER A N    1 ? 
ATOM   4404 C CA   . SER A 1 288 ? -39.993 -26.961 -21.039 1 59.085  ? 288 SER A CA   1 ? 
ATOM   4405 C C    . SER A 1 288 ? -39.74  -26.366 -19.654 1 51.405  ? 288 SER A C    1 ? 
ATOM   4406 O O    . SER A 1 288 ? -40.588 -26.48  -18.772 1 50.834  ? 288 SER A O    1 ? 
ATOM   4407 C CB   . SER A 1 288 ? -40.441 -28.414 -20.922 1 69.283  ? 288 SER A CB   1 ? 
ATOM   4408 O OG   . SER A 1 288 ? -40.782 -28.952 -22.194 1 77.212  ? 288 SER A OG   1 ? 
ATOM   4409 H H    . SER A 1 288 ? -38.097 -27.405 -21.683 1 58.496  ? 288 SER A H    1 c 
ATOM   4410 H HA   . SER A 1 288 ? -40.725 -26.447 -21.464 1 59.242  ? 288 SER A HA   1 c 
ATOM   4411 H HB2  . SER A 1 288 ? -39.721 -28.943 -20.529 1 68.581  ? 288 SER A HB2  1 c 
ATOM   4412 H HB3  . SER A 1 288 ? -41.216 -28.468 -20.332 1 68.493  ? 288 SER A HB3  1 c 
ATOM   4413 N N    . ASN A 1 289 ? -38.57  -25.744 -19.455 1 47.865  ? 289 ASN A N    1 ? 
ATOM   4414 C CA   . ASN A 1 289 ? -38.156 -25.342 -18.122 1 49.81   ? 289 ASN A CA   1 ? 
ATOM   4415 C C    . ASN A 1 289 ? -38.345 -23.828 -17.915 1 50.003  ? 289 ASN A C    1 ? 
ATOM   4416 O O    . ASN A 1 289 ? -37.965 -23.309 -16.866 1 43.992  ? 289 ASN A O    1 ? 
ATOM   4417 C CB   . ASN A 1 289 ? -36.764 -25.89  -17.843 1 45.702  ? 289 ASN A CB   1 ? 
ATOM   4418 C CG   . ASN A 1 289 ? -35.654 -25.182 -18.592 1 49.2    ? 289 ASN A CG   1 ? 
ATOM   4419 O OD1  . ASN A 1 289 ? -35.811 -24.825 -19.765 1 52.468  ? 289 ASN A OD1  1 ? 
ATOM   4420 N ND2  . ASN A 1 289 ? -34.519 -24.966 -17.938 1 45.004  ? 289 ASN A ND2  1 ? 
ATOM   4421 H H    . ASN A 1 289 ? -38.028 -25.543 -20.161 1 49.295  ? 289 ASN A H    1 c 
ATOM   4422 H HA   . ASN A 1 289 ? -38.751 -25.785 -17.478 1 48.696  ? 289 ASN A HA   1 c 
ATOM   4423 H HB2  . ASN A 1 289 ? -36.589 -25.825 -16.883 1 47.395  ? 289 ASN A HB2  1 c 
ATOM   4424 H HB3  . ASN A 1 289 ? -36.75  -26.837 -18.081 1 47.496  ? 289 ASN A HB3  1 c 
ATOM   4425 H HD21 . ASN A 1 289 ? -33.919 -24.407 -18.272 1 46.333  ? 289 ASN A HD21 1 c 
ATOM   4426 H HD22 . ASN A 1 289 ? -34.354 -25.384 -17.173 1 46.279  ? 289 ASN A HD22 1 c 
ATOM   4427 N N    . VAL A 1 290 ? -38.98  -23.127 -18.868 1 50.094  ? 290 VAL A N    1 ? 
ATOM   4428 C CA   . VAL A 1 290 ? -39.175 -21.683 -18.762 1 47.094  ? 290 VAL A CA   1 ? 
ATOM   4429 C C    . VAL A 1 290 ? -40.465 -21.396 -17.986 1 48.199  ? 290 VAL A C    1 ? 
ATOM   4430 O O    . VAL A 1 290 ? -41.537 -21.86  -18.358 1 49.472  ? 290 VAL A O    1 ? 
ATOM   4431 C CB   . VAL A 1 290 ? -39.196 -21.024 -20.148 1 44.634  ? 290 VAL A CB   1 ? 
ATOM   4432 C CG1  . VAL A 1 290 ? -39.312 -19.508 -20.046 1 50.597  ? 290 VAL A CG1  1 ? 
ATOM   4433 C CG2  . VAL A 1 290 ? -37.969 -21.396 -20.961 1 47.93   ? 290 VAL A CG2  1 ? 
ATOM   4434 H H    . VAL A 1 290 ? -39.31  -23.554 -19.605 1 49.324  ? 290 VAL A H    1 c 
ATOM   4435 H HA   . VAL A 1 290 ? -38.425 -21.309 -18.266 1 47.419  ? 290 VAL A HA   1 c 
ATOM   4436 H HB   . VAL A 1 290 ? -39.993 -21.36  -20.622 1 46.808  ? 290 VAL A HB   1 c 
ATOM   4437 H HG11 . VAL A 1 290 ? -38.701 -19.182 -19.364 1 48.727  ? 290 VAL A HG11 1 c 
ATOM   4438 H HG12 . VAL A 1 290 ? -40.219 -19.265 -19.804 1 48.819  ? 290 VAL A HG12 1 c 
ATOM   4439 H HG13 . VAL A 1 290 ? -39.089 -19.102 -20.9   1 48.751  ? 290 VAL A HG13 1 c 
ATOM   4440 H HG21 . VAL A 1 290 ? -37.933 -20.854 -21.767 1 46.973  ? 290 VAL A HG21 1 c 
ATOM   4441 H HG22 . VAL A 1 290 ? -38.014 -22.335 -21.208 1 46.972  ? 290 VAL A HG22 1 c 
ATOM   4442 H HG23 . VAL A 1 290 ? -37.169 -21.24  -20.431 1 46.947  ? 290 VAL A HG23 1 c 
ATOM   4443 N N    . LYS A 1 291 ? -40.373 -20.614 -16.908 1 48.309  ? 291 LYS A N    1 ? 
ATOM   4444 C CA   . LYS A 1 291 ? -41.508 -20.422 -16.017 1 53.116  ? 291 LYS A CA   1 ? 
ATOM   4445 C C    . LYS A 1 291 ? -42.103 -19.014 -16.138 1 54.36   ? 291 LYS A C    1 ? 
ATOM   4446 O O    . LYS A 1 291 ? -43.23  -18.805 -15.688 1 49.107  ? 291 LYS A O    1 ? 
ATOM   4447 C CB   . LYS A 1 291 ? -41.046 -20.715 -14.587 1 55.177  ? 291 LYS A CB   1 ? 
ATOM   4448 C CG   . LYS A 1 291 ? -40.914 -22.196 -14.23  1 64.398  ? 291 LYS A CG   1 ? 
ATOM   4449 C CD   . LYS A 1 291 ? -42.111 -22.791 -13.486 1 73.166  ? 291 LYS A CD   1 ? 
ATOM   4450 C CE   . LYS A 1 291 ? -41.696 -23.506 -12.215 1 79.824  ? 291 LYS A CE   1 ? 
ATOM   4451 N NZ   . LYS A 1 291 ? -42.781 -23.614 -11.236 1 85.122  ? 291 LYS A NZ   1 ? 
ATOM   4452 H H    . LYS A 1 291 ? -39.579 -20.207 -16.708 1 49.334  ? 291 LYS A H    1 c 
ATOM   4453 H HA   . LYS A 1 291 ? -42.214 -21.079 -16.245 1 52.689  ? 291 LYS A HA   1 c 
ATOM   4454 H HB2  . LYS A 1 291 ? -40.174 -20.289 -14.449 1 56.597  ? 291 LYS A HB2  1 c 
ATOM   4455 H HB3  . LYS A 1 291 ? -41.677 -20.298 -13.963 1 56.818  ? 291 LYS A HB3  1 c 
ATOM   4456 H HG2  . LYS A 1 291 ? -40.775 -22.703 -15.059 1 63.935  ? 291 LYS A HG2  1 c 
ATOM   4457 H HG3  . LYS A 1 291 ? -40.11  -22.304 -13.682 1 64.026  ? 291 LYS A HG3  1 c 
ATOM   4458 H HD2  . LYS A 1 291 ? -42.749 -22.081 -13.26  1 72.278  ? 291 LYS A HD2  1 c 
ATOM   4459 H HD3  . LYS A 1 291 ? -42.567 -23.429 -14.077 1 72.465  ? 291 LYS A HD3  1 c 
ATOM   4460 H HE2  . LYS A 1 291 ? -41.387 -24.402 -12.439 1 79.43   ? 291 LYS A HE2  1 c 
ATOM   4461 H HE3  . LYS A 1 291 ? -40.956 -23.032 -11.794 1 79.263  ? 291 LYS A HE3  1 c 
ATOM   4462 H HZ1  . LYS A 1 291 ? -43.515 -23.968 -11.631 1 83.455  ? 291 LYS A HZ1  1 c 
ATOM   4463 H HZ2  . LYS A 1 291 ? -42.984 -22.793 -10.912 1 83.455  ? 291 LYS A HZ2  1 c 
ATOM   4464 H HZ3  . LYS A 1 291 ? -42.523 -24.149 -10.552 1 83.455  ? 291 LYS A HZ3  1 c 
ATOM   4465 N N    . GLY A 1 292 ? -41.343 -18.052 -16.685 1 45.806  ? 292 GLY A N    1 ? 
ATOM   4466 C CA   . GLY A 1 292 ? -41.841 -16.696 -16.863 1 47.298  ? 292 GLY A CA   1 ? 
ATOM   4467 C C    . GLY A 1 292 ? -40.751 -15.707 -17.273 1 43.787  ? 292 GLY A C    1 ? 
ATOM   4468 O O    . GLY A 1 292 ? -39.679 -16.084 -17.759 1 42.772  ? 292 GLY A O    1 ? 
ATOM   4469 H H    . GLY A 1 292 ? -40.488 -18.237 -16.945 1 48.077  ? 292 GLY A H    1 c 
ATOM   4470 H HA2  . GLY A 1 292 ? -42.548 -16.704 -17.55  1 46.148  ? 292 GLY A HA2  1 c 
ATOM   4471 H HA3  . GLY A 1 292 ? -42.246 -16.396 -16.017 1 46.188  ? 292 GLY A HA3  1 c 
ATOM   4472 N N    . SER A 1 293 ? -41.043 -14.421 -17.066 1 43.011  ? 293 SER A N    1 ? 
ATOM   4473 C CA   . SER A 1 293 ? -40.1   -13.361 -17.386 1 40.905  ? 293 SER A CA   1 ? 
ATOM   4474 C C    . SER A 1 293 ? -40.311 -12.164 -16.456 1 35.297  ? 293 SER A C    1 ? 
ATOM   4475 O O    . SER A 1 293 ? -41.202 -12.164 -15.615 1 39.407  ? 293 SER A O    1 ? 
ATOM   4476 C CB   . SER A 1 293 ? -40.22  -12.975 -18.833 1 45.815  ? 293 SER A CB   1 ? 
ATOM   4477 O OG   . SER A 1 293 ? -41.515 -12.459 -19.1   1 50.764  ? 293 SER A OG   1 ? 
ATOM   4478 H H    . SER A 1 293 ? -41.858 -14.195 -16.719 1 42.711  ? 293 SER A H    1 c 
ATOM   4479 H HA   . SER A 1 293 ? -39.186 -13.705 -17.231 1 41.065  ? 293 SER A HA   1 c 
ATOM   4480 H HB2  . SER A 1 293 ? -39.548 -12.302 -19.049 1 45.649  ? 293 SER A HB2  1 c 
ATOM   4481 H HB3  . SER A 1 293 ? -40.06  -13.759 -19.392 1 45.731  ? 293 SER A HB3  1 c 
ATOM   4482 N N    . SER A 1 294 ? -39.43  -11.177 -16.564 1 36.512  ? 294 SER A N    1 ? 
ATOM   4483 C CA   . SER A 1 294 ? -39.527 -9.966  -15.767 1 46.618  ? 294 SER A CA   1 ? 
ATOM   4484 C C    . SER A 1 294 ? -38.813 -8.819  -16.459 1 45.196  ? 294 SER A C    1 ? 
ATOM   4485 O O    . SER A 1 294 ? -37.719 -9      -16.976 1 46.71   ? 294 SER A O    1 ? 
ATOM   4486 C CB   . SER A 1 294 ? -38.956 -10.157 -14.378 1 47.293  ? 294 SER A CB   1 ? 
ATOM   4487 O OG   . SER A 1 294 ? -38.906 -8.943  -13.632 1 44.379  ? 294 SER A OG   1 ? 
ATOM   4488 H H    . SER A 1 294 ? -38.728 -11.264 -17.144 1 38.433  ? 294 SER A H    1 c 
ATOM   4489 H HA   . SER A 1 294 ? -40.48  -9.736  -15.687 1 44.22   ? 294 SER A HA   1 c 
ATOM   4490 H HB2  . SER A 1 294 ? -39.499 -10.804 -13.898 1 46.39   ? 294 SER A HB2  1 c 
ATOM   4491 H HB3  . SER A 1 294 ? -38.058 -10.518 -14.46  1 46.359  ? 294 SER A HB3  1 c 
ATOM   4492 N N    . LEU A 1 295 ? -39.427 -7.638  -16.396 1 44.703  ? 295 LEU A N    1 ? 
ATOM   4493 C CA   . LEU A 1 295 ? -38.757 -6.398  -16.746 1 45.353  ? 295 LEU A CA   1 ? 
ATOM   4494 C C    . LEU A 1 295 ? -38.101 -5.876  -15.474 1 43.269  ? 295 LEU A C    1 ? 
ATOM   4495 O O    . LEU A 1 295 ? -38.72  -5.912  -14.413 1 41.014  ? 295 LEU A O    1 ? 
ATOM   4496 C CB   . LEU A 1 295 ? -39.804 -5.419  -17.282 1 48.468  ? 295 LEU A CB   1 ? 
ATOM   4497 C CG   . LEU A 1 295 ? -39.352 -3.969  -17.473 1 45.463  ? 295 LEU A CG   1 ? 
ATOM   4498 C CD1  . LEU A 1 295 ? -38.279 -3.878  -18.543 1 42.593  ? 295 LEU A CD1  1 ? 
ATOM   4499 C CD2  . LEU A 1 295 ? -40.557 -3.098  -17.794 1 48.157  ? 295 LEU A CD2  1 ? 
ATOM   4500 H H    . LEU A 1 295 ? -40.298 -7.601  -16.121 1 45.01   ? 295 LEU A H    1 c 
ATOM   4501 H HA   . LEU A 1 295 ? -38.073 -6.572  -17.439 1 45.351  ? 295 LEU A HA   1 c 
ATOM   4502 H HB2  . LEU A 1 295 ? -40.127 -5.76   -18.148 1 47.024  ? 295 LEU A HB2  1 c 
ATOM   4503 H HB3  . LEU A 1 295 ? -40.571 -5.421  -16.664 1 47.038  ? 295 LEU A HB3  1 c 
ATOM   4504 H HG   . LEU A 1 295 ? -38.965 -3.643  -16.621 1 45.922  ? 295 LEU A HG   1 c 
ATOM   4505 H HD11 . LEU A 1 295 ? -37.414 -4.083  -18.153 1 43.43   ? 295 LEU A HD11 1 c 
ATOM   4506 H HD12 . LEU A 1 295 ? -38.26  -2.977  -18.909 1 43.482  ? 295 LEU A HD12 1 c 
ATOM   4507 H HD13 . LEU A 1 295 ? -38.471 -4.511  -19.255 1 43.482  ? 295 LEU A HD13 1 c 
ATOM   4508 H HD21 . LEU A 1 295 ? -41.2   -3.153  -17.068 1 47.337  ? 295 LEU A HD21 1 c 
ATOM   4509 H HD22 . LEU A 1 295 ? -40.972 -3.408  -18.617 1 47.339  ? 295 LEU A HD22 1 c 
ATOM   4510 H HD23 . LEU A 1 295 ? -40.271 -2.176  -17.904 1 47.318  ? 295 LEU A HD23 1 c 
ATOM   4511 N N    . THR A 1 296 ? -36.878 -5.354  -15.58  1 40.987  ? 296 THR A N    1 ? 
ATOM   4512 C CA   . THR A 1 296 ? -36.17  -4.918  -14.386 1 44.661  ? 296 THR A CA   1 ? 
ATOM   4513 C C    . THR A 1 296 ? -35.768 -3.448  -14.521 1 45.375  ? 296 THR A C    1 ? 
ATOM   4514 O O    . THR A 1 296 ? -35.161 -3.071  -15.524 1 45.763  ? 296 THR A O    1 ? 
ATOM   4515 C CB   . THR A 1 296 ? -34.958 -5.83   -14.155 1 41.674  ? 296 THR A CB   1 ? 
ATOM   4516 O OG1  . THR A 1 296 ? -35.485 -7.146  -14.011 1 42.396  ? 296 THR A OG1  1 ? 
ATOM   4517 C CG2  . THR A 1 296 ? -34.189 -5.452  -12.903 1 41.083  ? 296 THR A CG2  1 ? 
ATOM   4518 H H    . THR A 1 296 ? -36.475 -5.273  -16.396 1 42.379  ? 296 THR A H    1 c 
ATOM   4519 H HA   . THR A 1 296 ? -36.764 -5.009  -13.617 1 43.465  ? 296 THR A HA   1 c 
ATOM   4520 H HB   . THR A 1 296 ? -34.357 -5.797  -14.937 1 42.227  ? 296 THR A HB   1 c 
ATOM   4521 H HG21 . THR A 1 296 ? -33.705 -6.228  -12.572 1 41.288  ? 296 THR A HG21 1 c 
ATOM   4522 H HG22 . THR A 1 296 ? -34.809 -5.144  -12.221 1 41.312  ? 296 THR A HG22 1 c 
ATOM   4523 H HG23 . THR A 1 296 ? -33.559 -4.743  -13.11  1 41.332  ? 296 THR A HG23 1 c 
ATOM   4524 N N    . PHE A 1 297 ? -36.066 -2.646  -13.485 1 41.218  ? 297 PHE A N    1 ? 
ATOM   4525 C CA   . PHE A 1 297 ? -35.56  -1.28   -13.398 1 44.369  ? 297 PHE A CA   1 ? 
ATOM   4526 C C    . PHE A 1 297 ? -34.355 -1.23   -12.455 1 46.772  ? 297 PHE A C    1 ? 
ATOM   4527 O O    . PHE A 1 297 ? -34.498 -1.315  -11.229 1 45.966  ? 297 PHE A O    1 ? 
ATOM   4528 C CB   . PHE A 1 297 ? -36.672 -0.316  -12.958 1 43.304  ? 297 PHE A CB   1 ? 
ATOM   4529 C CG   . PHE A 1 297 ? -37.903 -0.338  -13.856 1 41.079  ? 297 PHE A CG   1 ? 
ATOM   4530 C CD1  . PHE A 1 297 ? -37.854 0.176   -15.143 1 45.012  ? 297 PHE A CD1  1 ? 
ATOM   4531 C CD2  . PHE A 1 297 ? -39.105 -0.849  -13.399 1 44.084  ? 297 PHE A CD2  1 ? 
ATOM   4532 C CE1  . PHE A 1 297 ? -38.971 0.154   -15.958 1 44.216  ? 297 PHE A CE1  1 ? 
ATOM   4533 C CE2  . PHE A 1 297 ? -40.222 -0.86   -14.21  1 46.839  ? 297 PHE A CE2  1 ? 
ATOM   4534 C CZ   . PHE A 1 297 ? -40.153 -0.37   -15.49  1 47.006  ? 297 PHE A CZ   1 ? 
ATOM   4535 H H    . PHE A 1 297 ? -36.603 -2.956  -12.813 1 42.895  ? 297 PHE A H    1 c 
ATOM   4536 H HA   . PHE A 1 297 ? -35.267 -1.002  -14.295 1 44.069  ? 297 PHE A HA   1 c 
ATOM   4537 H HB2  . PHE A 1 297 ? -36.941 -0.546  -12.041 1 43.05   ? 297 PHE A HB2  1 c 
ATOM   4538 H HB3  . PHE A 1 297 ? -36.305 0.597   -12.944 1 43.028  ? 297 PHE A HB3  1 c 
ATOM   4539 H HD1  . PHE A 1 297 ? -37.042 0.528   -15.472 1 43.922  ? 297 PHE A HD1  1 c 
ATOM   4540 H HD2  . PHE A 1 297 ? -39.16  -1.196  -12.524 1 44.012  ? 297 PHE A HD2  1 c 
ATOM   4541 H HE1  . PHE A 1 297 ? -38.921 0.499   -16.835 1 45.034  ? 297 PHE A HE1  1 c 
ATOM   4542 H HE2  . PHE A 1 297 ? -41.031 -1.222  -13.887 1 46.167  ? 297 PHE A HE2  1 c 
ATOM   4543 H HZ   . PHE A 1 297 ? -40.917 -0.376  -16.042 1 46.249  ? 297 PHE A HZ   1 c 
ATOM   4544 N N    . TRP A 1 298 ? -33.157 -1.084  -13.035 1 45.823  ? 298 TRP A N    1 ? 
ATOM   4545 C CA   . TRP A 1 298 ? -31.951 -0.866  -12.246 1 55.085  ? 298 TRP A CA   1 ? 
ATOM   4546 C C    . TRP A 1 298 ? -31.816 0.626   -11.922 1 53.783  ? 298 TRP A C    1 ? 
ATOM   4547 O O    . TRP A 1 298 ? -32.059 1.463   -12.785 1 55.742  ? 298 TRP A O    1 ? 
ATOM   4548 C CB   . TRP A 1 298 ? -30.704 -1.412  -12.974 1 53.169  ? 298 TRP A CB   1 ? 
ATOM   4549 C CG   . TRP A 1 298 ? -30.727 -2.906  -13.155 1 49.308  ? 298 TRP A CG   1 ? 
ATOM   4550 C CD1  . TRP A 1 298 ? -30.99  -3.59   -14.305 1 51.71   ? 298 TRP A CD1  1 ? 
ATOM   4551 C CD2  . TRP A 1 298 ? -30.539 -3.902  -12.128 1 48.024  ? 298 TRP A CD2  1 ? 
ATOM   4552 N NE1  . TRP A 1 298 ? -30.97  -4.937  -14.071 1 50.557  ? 298 TRP A NE1  1 ? 
ATOM   4553 C CE2  . TRP A 1 298 ? -30.707 -5.164  -12.747 1 52.838  ? 298 TRP A CE2  1 ? 
ATOM   4554 C CE3  . TRP A 1 298 ? -30.261 -3.854  -10.754 1 44.815  ? 298 TRP A CE3  1 ? 
ATOM   4555 C CZ2  . TRP A 1 298 ? -30.601 -6.36   -12.036 1 50.404  ? 298 TRP A CZ2  1 ? 
ATOM   4556 C CZ3  . TRP A 1 298 ? -30.127 -5.036  -10.061 1 51.326  ? 298 TRP A CZ3  1 ? 
ATOM   4557 C CH2  . TRP A 1 298 ? -30.304 -6.272  -10.691 1 51.359  ? 298 TRP A CH2  1 ? 
ATOM   4558 H H    . TRP A 1 298 ? -33.085 -1.128  -13.945 1 47.969  ? 298 TRP A H    1 c 
ATOM   4559 H HA   . TRP A 1 298 ? -32.041 -1.365  -11.392 1 52.404  ? 298 TRP A HA   1 c 
ATOM   4560 H HB2  . TRP A 1 298 ? -30.647 -0.989  -13.856 1 52.799  ? 298 TRP A HB2  1 c 
ATOM   4561 H HB3  . TRP A 1 298 ? -29.909 -1.17   -12.456 1 52.719  ? 298 TRP A HB3  1 c 
ATOM   4562 H HD1  . TRP A 1 298 ? -31.162 -3.198  -15.146 1 50.884  ? 298 TRP A HD1  1 c 
ATOM   4563 H HE1  . TRP A 1 298 ? -31.112 -5.538  -14.659 1 51.216  ? 298 TRP A HE1  1 c 
ATOM   4564 H HE3  . TRP A 1 298 ? -30.137 -3.03   -10.323 1 47.243  ? 298 TRP A HE3  1 c 
ATOM   4565 H HZ2  . TRP A 1 298 ? -30.704 -7.193  -12.463 1 51.12   ? 298 TRP A HZ2  1 c 
ATOM   4566 H HZ3  . TRP A 1 298 ? -29.944 -5.011  -9.139  1 49.731  ? 298 TRP A HZ3  1 c 
ATOM   4567 H HH2  . TRP A 1 298 ? -30.223 -7.062  -10.187 1 51.07   ? 298 TRP A HH2  1 c 
ATOM   4568 N N    . GLY A 1 299 ? -31.366 0.93    -10.697 1 53.561  ? 299 GLY A N    1 ? 
ATOM   4569 C CA   . GLY A 1 299 ? -31.439 2.257   -10.108 1 56.312  ? 299 GLY A CA   1 ? 
ATOM   4570 C C    . GLY A 1 299 ? -30.23  3.165   -10.365 1 58.82   ? 299 GLY A C    1 ? 
ATOM   4571 O O    . GLY A 1 299 ? -30.343 4.367   -10.148 1 67.415  ? 299 GLY A O    1 ? 
ATOM   4572 H H    . GLY A 1 299 ? -30.958 0.272   -10.214 1 54.13   ? 299 GLY A H    1 c 
ATOM   4573 H HA2  . GLY A 1 299 ? -32.249 2.705   -10.449 1 56.168  ? 299 GLY A HA2  1 c 
ATOM   4574 H HA3  . GLY A 1 299 ? -31.553 2.154   -9.134  1 56.182  ? 299 GLY A HA3  1 c 
ATOM   4575 N N    . GLU A 1 300 ? -29.091 2.651   -10.854 1 59.9    ? 300 GLU A N    1 ? 
ATOM   4576 C CA   . GLU A 1 300 ? -27.832 3.393   -10.746 1 66.681  ? 300 GLU A CA   1 ? 
ATOM   4577 C C    . GLU A 1 300 ? -27.715 4.575   -11.724 1 69.482  ? 300 GLU A C    1 ? 
ATOM   4578 O O    . GLU A 1 300 ? -26.732 5.308   -11.659 1 71.429  ? 300 GLU A O    1 ? 
ATOM   4579 C CB   . GLU A 1 300 ? -26.585 2.51    -10.851 1 65.916  ? 300 GLU A CB   1 ? 
ATOM   4580 C CG   . GLU A 1 300 ? -26.486 1.699   -12.138 1 67.715  ? 300 GLU A CG   1 ? 
ATOM   4581 C CD   . GLU A 1 300 ? -27.019 0.285   -11.997 1 64.026  ? 300 GLU A CD   1 ? 
ATOM   4582 O OE1  . GLU A 1 300 ? -28.182 0.108   -11.564 1 57.208  ? 300 GLU A OE1  1 ? 
ATOM   4583 O OE2  . GLU A 1 300 ? -26.242 -0.636  -12.305 1 62.77   ? 300 GLU A OE2  1 ? 
ATOM   4584 H H    . GLU A 1 300 ? -29.099 1.839   -11.269 1 61.082  ? 300 GLU A H    1 c 
ATOM   4585 H HA   . GLU A 1 300 ? -27.8   3.776   -9.832  1 65.632  ? 300 GLU A HA   1 c 
ATOM   4586 H HB2  . GLU A 1 300 ? -25.789 3.076   -10.78  1 66.53   ? 300 GLU A HB2  1 c 
ATOM   4587 H HB3  . GLU A 1 300 ? -26.576 1.894   -10.089 1 66.456  ? 300 GLU A HB3  1 c 
ATOM   4588 H HG2  . GLU A 1 300 ? -26.987 2.151   -12.849 1 66.454  ? 300 GLU A HG2  1 c 
ATOM   4589 H HG3  . GLU A 1 300 ? -25.546 1.654   -12.417 1 66.423  ? 300 GLU A HG3  1 c 
ATOM   4590 N N    . HIS A 1 301 ? -28.684 4.772   -12.63  1 63.907  ? 301 HIS A N    1 ? 
ATOM   4591 C CA   . HIS A 1 301 ? -28.715 5.956   -13.472 1 64.093  ? 301 HIS A CA   1 ? 
ATOM   4592 C C    . HIS A 1 301 ? -29.809 6.917   -13.019 1 66.22   ? 301 HIS A C    1 ? 
ATOM   4593 O O    . HIS A 1 301 ? -29.946 7.993   -13.596 1 68.176  ? 301 HIS A O    1 ? 
ATOM   4594 C CB   . HIS A 1 301 ? -28.923 5.582   -14.945 1 66.108  ? 301 HIS A CB   1 ? 
ATOM   4595 C CG   . HIS A 1 301 ? -27.732 4.979   -15.602 1 60.628  ? 301 HIS A CG   1 ? 
ATOM   4596 N ND1  . HIS A 1 301 ? -27.79  4.423   -16.865 1 55.323  ? 301 HIS A ND1  1 ? 
ATOM   4597 C CD2  . HIS A 1 301 ? -26.462 4.88    -15.19  1 56.881  ? 301 HIS A CD2  1 ? 
ATOM   4598 C CE1  . HIS A 1 301 ? -26.581 4.011   -17.205 1 62.603  ? 301 HIS A CE1  1 ? 
ATOM   4599 N NE2  . HIS A 1 301 ? -25.758 4.271   -16.196 1 61.253  ? 301 HIS A NE2  1 ? 
ATOM   4600 H H    . HIS A 1 301 ? -29.322 4.131   -12.76  1 65.178  ? 301 HIS A H    1 c 
ATOM   4601 H HA   . HIS A 1 301 ? -27.852 6.431   -13.399 1 64.798  ? 301 HIS A HA   1 c 
ATOM   4602 H HB2  . HIS A 1 301 ? -29.67  4.955   -15.01  1 64.207  ? 301 HIS A HB2  1 c 
ATOM   4603 H HB3  . HIS A 1 301 ? -29.179 6.389   -15.444 1 64.338  ? 301 HIS A HB3  1 c 
ATOM   4604 H HD2  . HIS A 1 301 ? -26.106 5.173   -14.375 1 58.815  ? 301 HIS A HD2  1 c 
ATOM   4605 H HE1  . HIS A 1 301 ? -26.351 3.581   -18.011 1 60.51   ? 301 HIS A HE1  1 c 
ATOM   4606 N N    . ALA A 1 302 ? -30.558 6.539   -11.974 1 68.995  ? 302 ALA A N    1 ? 
ATOM   4607 C CA   . ALA A 1 302 ? -31.741 7.267   -11.555 1 68.525  ? 302 ALA A CA   1 ? 
ATOM   4608 C C    . ALA A 1 302 ? -31.399 8.367   -10.546 1 77.486  ? 302 ALA A C    1 ? 
ATOM   4609 O O    . ALA A 1 302 ? -32.308 8.877   -9.89   1 67.781  ? 302 ALA A O    1 ? 
ATOM   4610 C CB   . ALA A 1 302 ? -32.742 6.294   -10.976 1 65.1    ? 302 ALA A CB   1 ? 
ATOM   4611 H H    . ALA A 1 302 ? -30.31  5.81    -11.484 1 68.064  ? 302 ALA A H    1 c 
ATOM   4612 H HA   . ALA A 1 302 ? -32.146 7.699   -12.358 1 69.487  ? 302 ALA A HA   1 c 
ATOM   4613 H HB1  . ALA A 1 302 ? -32.812 5.514   -11.553 1 66.131  ? 302 ALA A HB1  1 c 
ATOM   4614 H HB2  . ALA A 1 302 ? -32.452 6.014   -10.092 1 66.232  ? 302 ALA A HB2  1 c 
ATOM   4615 H HB3  . ALA A 1 302 ? -33.613 6.721   -10.908 1 66.137  ? 302 ALA A HB3  1 c 
ATOM   4616 N N    . THR A 1 303 ? -30.112 8.755   -10.471 1 80.191  ? 303 THR A N    1 ? 
ATOM   4617 C CA   . THR A 1 303 ? -29.574 9.569   -9.388  1 91.278  ? 303 THR A CA   1 ? 
ATOM   4618 C C    . THR A 1 303 ? -30.496 10.76   -9.125  1 91.181  ? 303 THR A C    1 ? 
ATOM   4619 O O    . THR A 1 303 ? -31.062 10.861  -8.034  1 81.788  ? 303 THR A O    1 ? 
ATOM   4620 C CB   . THR A 1 303 ? -28.154 10.026  -9.738  1 102.01  ? 303 THR A CB   1 ? 
ATOM   4621 O OG1  . THR A 1 303 ? -27.496 8.921   -10.357 1 99.428  ? 303 THR A OG1  1 ? 
ATOM   4622 C CG2  . THR A 1 303 ? -27.382 10.51   -8.521  1 102.087 ? 303 THR A CG2  1 ? 
ATOM   4623 H H    . THR A 1 303 ? -29.543 8.528   -11.148 1 81.726  ? 303 THR A H    1 c 
ATOM   4624 H HA   . THR A 1 303 ? -29.533 9.016   -8.578  1 90.817  ? 303 THR A HA   1 c 
ATOM   4625 H HB   . THR A 1 303 ? -28.198 10.769  -10.386 1 99.286  ? 303 THR A HB   1 c 
ATOM   4626 H HG21 . THR A 1 303 ? -26.455 10.668  -8.766  1 102.033 ? 303 THR A HG21 1 c 
ATOM   4627 H HG22 . THR A 1 303 ? -27.421 9.836   -7.822  1 101.971 ? 303 THR A HG22 1 c 
ATOM   4628 H HG23 . THR A 1 303 ? -27.775 11.337  -8.194  1 101.993 ? 303 THR A HG23 1 c 
ATOM   4629 N N    . ASP A 1 304 ? -30.698 11.591  -10.164 1 83.823  ? 304 ASP A N    1 ? 
ATOM   4630 C CA   . ASP A 1 304 ? -31.378 12.877  -10.054 1 91.672  ? 304 ASP A CA   1 ? 
ATOM   4631 C C    . ASP A 1 304 ? -32.818 12.809  -10.568 1 81.65   ? 304 ASP A C    1 ? 
ATOM   4632 O O    . ASP A 1 304 ? -33.296 13.774  -11.153 1 75.952  ? 304 ASP A O    1 ? 
ATOM   4633 C CB   . ASP A 1 304 ? -30.644 13.961  -10.833 1 97.531  ? 304 ASP A CB   1 ? 
ATOM   4634 C CG   . ASP A 1 304 ? -29.201 14.213  -10.42  1 108.621 ? 304 ASP A CG   1 ? 
ATOM   4635 O OD1  . ASP A 1 304 ? -28.966 14.482  -9.221  1 111.035 ? 304 ASP A OD1  1 ? 
ATOM   4636 O OD2  . ASP A 1 304 ? -28.321 14.152  -11.306 1 117.38  ? 304 ASP A OD2  1 ? 
ATOM   4637 H H    . ASP A 1 304 ? -30.396 11.338  -10.989 1 87.408  ? 304 ASP A H    1 c 
ATOM   4638 H HA   . ASP A 1 304 ? -31.394 13.147  -9.108  1 89.201  ? 304 ASP A HA   1 c 
ATOM   4639 H HB2  . ASP A 1 304 ? -30.659 13.73   -11.785 1 98.409  ? 304 ASP A HB2  1 c 
ATOM   4640 H HB3  . ASP A 1 304 ? -31.115 14.813  -10.721 1 98.341  ? 304 ASP A HB3  1 c 
ATOM   4641 N N    . LEU A 1 305 ? -33.517 11.691  -10.338 1 75.636  ? 305 LEU A N    1 ? 
ATOM   4642 C CA   . LEU A 1 305 ? -34.913 11.571  -10.725 1 73.339  ? 305 LEU A CA   1 ? 
ATOM   4643 C C    . LEU A 1 305 ? -35.797 11.845  -9.515  1 72.932  ? 305 LEU A C    1 ? 
ATOM   4644 O O    . LEU A 1 305 ? -35.521 11.323  -8.437  1 67.1    ? 305 LEU A O    1 ? 
ATOM   4645 C CB   . LEU A 1 305 ? -35.219 10.202  -11.335 1 75.744  ? 305 LEU A CB   1 ? 
ATOM   4646 C CG   . LEU A 1 305 ? -35.02  10.086  -12.849 1 79.581  ? 305 LEU A CG   1 ? 
ATOM   4647 C CD1  . LEU A 1 305 ? -35.282 8.669   -13.303 1 77.407  ? 305 LEU A CD1  1 ? 
ATOM   4648 C CD2  . LEU A 1 305 ? -35.933 11.032  -13.602 1 81.989  ? 305 LEU A CD2  1 ? 
ATOM   4649 H H    . LEU A 1 305 ? -33.116 10.984  -9.924  1 76.789  ? 305 LEU A H    1 c 
ATOM   4650 H HA   . LEU A 1 305 ? -35.102 12.265  -11.398 1 74.169  ? 305 LEU A HA   1 c 
ATOM   4651 H HB2  . LEU A 1 305 ? -34.65  9.531   -10.893 1 76.006  ? 305 LEU A HB2  1 c 
ATOM   4652 H HB3  . LEU A 1 305 ? -36.156 9.974   -11.13  1 76.016  ? 305 LEU A HB3  1 c 
ATOM   4653 H HG   . LEU A 1 305 ? -34.079 10.317  -13.061 1 78.891  ? 305 LEU A HG   1 c 
ATOM   4654 H HD11 . LEU A 1 305 ? -34.746 8.053   -12.775 1 78.009  ? 305 LEU A HD11 1 c 
ATOM   4655 H HD12 . LEU A 1 305 ? -35.046 8.58    -14.241 1 77.981  ? 305 LEU A HD12 1 c 
ATOM   4656 H HD13 . LEU A 1 305 ? -36.224 8.459   -13.186 1 77.985  ? 305 LEU A HD13 1 c 
ATOM   4657 H HD21 . LEU A 1 305 ? -35.672 11.952  -13.432 1 81.123  ? 305 LEU A HD21 1 c 
ATOM   4658 H HD22 . LEU A 1 305 ? -36.845 10.893  -13.31  1 81.105  ? 305 LEU A HD22 1 c 
ATOM   4659 H HD23 . LEU A 1 305 ? -35.87  10.852  -14.555 1 81.188  ? 305 LEU A HD23 1 c 
ATOM   4660 N N    . SER A 1 306 ? -36.846 12.662  -9.72   1 65.102  ? 306 SER A N    1 ? 
ATOM   4661 C CA   . SER A 1 306 ? -37.914 12.833  -8.746  1 65.957  ? 306 SER A CA   1 ? 
ATOM   4662 C C    . SER A 1 306 ? -38.787 11.585  -8.732  1 58.485  ? 306 SER A C    1 ? 
ATOM   4663 O O    . SER A 1 306 ? -38.772 10.825  -9.692  1 64.396  ? 306 SER A O    1 ? 
ATOM   4664 C CB   . SER A 1 306 ? -38.756 14.059  -9.062  1 73.721  ? 306 SER A CB   1 ? 
ATOM   4665 O OG   . SER A 1 306 ? -39.21  14.041  -10.412 1 71.385  ? 306 SER A OG   1 ? 
ATOM   4666 H H    . SER A 1 306 ? -36.895 13.133  -10.502 1 67.228  ? 306 SER A H    1 c 
ATOM   4667 H HA   . SER A 1 306 ? -37.509 12.948  -7.849  1 65.669  ? 306 SER A HA   1 c 
ATOM   4668 H HB2  . SER A 1 306 ? -39.525 14.087  -8.462  1 71.273  ? 306 SER A HB2  1 c 
ATOM   4669 H HB3  . SER A 1 306 ? -38.224 14.863  -8.911  1 71.334  ? 306 SER A HB3  1 c 
ATOM   4670 N N    . GLN A 1 307 ? -39.568 11.417  -7.664  1 52.202  ? 307 GLN A N    1 ? 
ATOM   4671 C CA   . GLN A 1 307 ? -40.549 10.351  -7.574  1 67.326  ? 307 GLN A CA   1 ? 
ATOM   4672 C C    . GLN A 1 307 ? -41.511 10.406  -8.758  1 74.14   ? 307 GLN A C    1 ? 
ATOM   4673 O O    . GLN A 1 307 ? -41.845 9.356   -9.312  1 78.154  ? 307 GLN A O    1 ? 
ATOM   4674 C CB   . GLN A 1 307 ? -41.282 10.394  -6.229  1 64.002  ? 307 GLN A CB   1 ? 
ATOM   4675 C CG   . GLN A 1 307 ? -40.377 10.052  -5.046  1 68.498  ? 307 GLN A CG   1 ? 
ATOM   4676 C CD   . GLN A 1 307 ? -39.699 8.699   -5.177  1 63.257  ? 307 GLN A CD   1 ? 
ATOM   4677 O OE1  . GLN A 1 307 ? -40.334 7.644   -5.113  1 56.37   ? 307 GLN A OE1  1 ? 
ATOM   4678 N NE2  . GLN A 1 307 ? -38.393 8.718   -5.386  1 60.689  ? 307 GLN A NE2  1 ? 
ATOM   4679 H H    . GLN A 1 307 ? -39.488 11.998  -6.962  1 57.1    ? 307 GLN A H    1 c 
ATOM   4680 H HA   . GLN A 1 307 ? -40.061 9.493   -7.634  1 64.68   ? 307 GLN A HA   1 c 
ATOM   4681 H HB2  . GLN A 1 307 ? -41.653 11.291  -6.098  1 65.75   ? 307 GLN A HB2  1 c 
ATOM   4682 H HB3  . GLN A 1 307 ? -42.03  9.762   -6.254  1 65.76   ? 307 GLN A HB3  1 c 
ATOM   4683 H HG2  . GLN A 1 307 ? -39.688 10.744  -4.956  1 66.105  ? 307 GLN A HG2  1 c 
ATOM   4684 H HG3  . GLN A 1 307 ? -40.91  10.055  -4.222  1 66.208  ? 307 GLN A HG3  1 c 
ATOM   4685 H HE21 . GLN A 1 307 ? -37.869 8.141   -4.963  1 61.476  ? 307 GLN A HE21 1 c 
ATOM   4686 H HE22 . GLN A 1 307 ? -38.043 9.307   -5.949  1 61.503  ? 307 GLN A HE22 1 c 
ATOM   4687 N N    . LYS A 1 308 ? -41.923 11.621  -9.149  1 69.745  ? 308 LYS A N    1 ? 
ATOM   4688 C CA   . LYS A 1 308 ? -42.882 11.8    -10.226 1 68.385  ? 308 LYS A CA   1 ? 
ATOM   4689 C C    . LYS A 1 308 ? -42.26  11.366  -11.55  1 62.179  ? 308 LYS A C    1 ? 
ATOM   4690 O O    . LYS A 1 308 ? -42.937 10.761  -12.376 1 61.277  ? 308 LYS A O    1 ? 
ATOM   4691 C CB   . LYS A 1 308 ? -43.37  13.252  -10.367 1 77.728  ? 308 LYS A CB   1 ? 
ATOM   4692 C CG   . LYS A 1 308 ? -44.195 13.813  -9.214  1 84.539  ? 308 LYS A CG   1 ? 
ATOM   4693 C CD   . LYS A 1 308 ? -44.712 15.225  -9.479  1 94.476  ? 308 LYS A CD   1 ? 
ATOM   4694 C CE   . LYS A 1 308 ? -45.262 15.912  -8.259  1 96.487  ? 308 LYS A CE   1 ? 
ATOM   4695 N NZ   . LYS A 1 308 ? -46.298 16.896  -8.588  1 96.372  ? 308 LYS A NZ   1 ? 
ATOM   4696 H H    . LYS A 1 308 ? -41.608 12.363  -8.719  1 70.263  ? 308 LYS A H    1 c 
ATOM   4697 H HA   . LYS A 1 308 ? -43.665 11.222  -10.042 1 69.115  ? 308 LYS A HA   1 c 
ATOM   4698 H HB2  . LYS A 1 308 ? -42.585 13.828  -10.488 1 76.955  ? 308 LYS A HB2  1 c 
ATOM   4699 H HB3  . LYS A 1 308 ? -43.909 13.317  -11.185 1 76.884  ? 308 LYS A HB3  1 c 
ATOM   4700 H HG2  . LYS A 1 308 ? -44.959 13.216  -9.054  1 85.051  ? 308 LYS A HG2  1 c 
ATOM   4701 H HG3  . LYS A 1 308 ? -43.64  13.82   -8.404  1 85.051  ? 308 LYS A HG3  1 c 
ATOM   4702 H HD2  . LYS A 1 308 ? -43.978 15.766  -9.844  1 92.576  ? 308 LYS A HD2  1 c 
ATOM   4703 H HD3  . LYS A 1 308 ? -45.413 15.178  -10.161 1 92.589  ? 308 LYS A HD3  1 c 
ATOM   4704 H HE2  . LYS A 1 308 ? -45.624 15.255  -7.641  1 95.801  ? 308 LYS A HE2  1 c 
ATOM   4705 H HE3  . LYS A 1 308 ? -44.534 16.372  -7.804  1 95.959  ? 308 LYS A HE3  1 c 
ATOM   4706 H HZ1  . LYS A 1 308 ? -47.074 16.472  -8.782  1 96.404  ? 308 LYS A HZ1  1 c 
ATOM   4707 H HZ2  . LYS A 1 308 ? -46.042 17.394  -9.301  1 96.395  ? 308 LYS A HZ2  1 c 
ATOM   4708 H HZ3  . LYS A 1 308 ? -46.425 17.44   -7.875  1 96.404  ? 308 LYS A HZ3  1 c 
ATOM   4709 N N    . LYS A 1 309 ? -40.984 11.697  -11.769 1 61.911  ? 309 LYS A N    1 ? 
ATOM   4710 C CA   . LYS A 1 309 ? -40.388 11.465  -13.077 1 72.04   ? 309 LYS A CA   1 ? 
ATOM   4711 C C    . LYS A 1 309 ? -40.044 9.977   -13.224 1 71.311  ? 309 LYS A C    1 ? 
ATOM   4712 O O    . LYS A 1 309 ? -39.933 9.47    -14.333 1 64.151  ? 309 LYS A O    1 ? 
ATOM   4713 C CB   . LYS A 1 309 ? -39.24  12.452  -13.313 1 71.665  ? 309 LYS A CB   1 ? 
ATOM   4714 C CG   . LYS A 1 309 ? -38.941 12.74   -14.792 1 76.258  ? 309 LYS A CG   1 ? 
ATOM   4715 C CD   . LYS A 1 309 ? -38.413 14.14   -15.103 1 78.558  ? 309 LYS A CD   1 ? 
ATOM   4716 C CE   . LYS A 1 309 ? -36.974 14.209  -15.5   1 80.826  ? 309 LYS A CE   1 ? 
ATOM   4717 N NZ   . LYS A 1 309 ? -36.789 14.021  -16.945 1 79.489  ? 309 LYS A NZ   1 ? 
ATOM   4718 H H    . LYS A 1 309 ? -40.479 12.074  -11.108 1 64.339  ? 309 LYS A H    1 c 
ATOM   4719 H HA   . LYS A 1 309 ? -41.075 11.676  -13.76  1 69.729  ? 309 LYS A HA   1 c 
ATOM   4720 H HB2  . LYS A 1 309 ? -39.468 13.298  -12.876 1 72.645  ? 309 LYS A HB2  1 c 
ATOM   4721 H HB3  . LYS A 1 309 ? -38.431 12.109  -12.886 1 72.849  ? 309 LYS A HB3  1 c 
ATOM   4722 H HG2  . LYS A 1 309 ? -38.288 12.078  -15.106 1 75.741  ? 309 LYS A HG2  1 c 
ATOM   4723 H HG3  . LYS A 1 309 ? -39.765 12.599  -15.307 1 75.645  ? 309 LYS A HG3  1 c 
ATOM   4724 H HD2  . LYS A 1 309 ? -38.956 14.518  -15.829 1 78.547  ? 309 LYS A HD2  1 c 
ATOM   4725 H HD3  . LYS A 1 309 ? -38.548 14.713  -14.318 1 78.47   ? 309 LYS A HD3  1 c 
ATOM   4726 H HE2  . LYS A 1 309 ? -36.616 15.078  -15.247 1 79.944  ? 309 LYS A HE2  1 c 
ATOM   4727 H HE3  . LYS A 1 309 ? -36.473 13.523  -15.025 1 79.911  ? 309 LYS A HE3  1 c 
ATOM   4728 H HZ1  . LYS A 1 309 ? -37.154 14.718  -17.394 1 79.887  ? 309 LYS A HZ1  1 c 
ATOM   4729 H HZ2  . LYS A 1 309 ? -37.192 13.253  -17.209 1 79.888  ? 309 LYS A HZ2  1 c 
ATOM   4730 H HZ3  . LYS A 1 309 ? -35.905 13.974  -17.137 1 79.894  ? 309 LYS A HZ3  1 c 
ATOM   4731 N N    . LEU A 1 310 ? -39.907 9.287   -12.087 1 72.067  ? 310 LEU A N    1 ? 
ATOM   4732 C CA   . LEU A 1 310 ? -39.669 7.854   -12.035 1 69.558  ? 310 LEU A CA   1 ? 
ATOM   4733 C C    . LEU A 1 310 ? -40.942 7.131   -12.476 1 69.922  ? 310 LEU A C    1 ? 
ATOM   4734 O O    . LEU A 1 310 ? -40.904 6.224   -13.311 1 59.261  ? 310 LEU A O    1 ? 
ATOM   4735 C CB   . LEU A 1 310 ? -39.285 7.537   -10.586 1 66.606  ? 310 LEU A CB   1 ? 
ATOM   4736 C CG   . LEU A 1 310 ? -38.358 6.352   -10.323 1 67.702  ? 310 LEU A CG   1 ? 
ATOM   4737 C CD1  . LEU A 1 310 ? -37.064 6.477   -11.107 1 73.335  ? 310 LEU A CD1  1 ? 
ATOM   4738 C CD2  . LEU A 1 310 ? -38.084 6.281   -8.826  1 63.648  ? 310 LEU A CD2  1 ? 
ATOM   4739 H H    . LEU A 1 310 ? -39.951 9.741   -11.296 1 71.056  ? 310 LEU A H    1 c 
ATOM   4740 H HA   . LEU A 1 310 ? -38.926 7.627   -12.647 1 69.567  ? 310 LEU A HA   1 c 
ATOM   4741 H HB2  . LEU A 1 310 ? -38.856 8.333   -10.2   1 67.508  ? 310 LEU A HB2  1 c 
ATOM   4742 H HB3  . LEU A 1 310 ? -40.114 7.395   -10.073 1 67.465  ? 310 LEU A HB3  1 c 
ATOM   4743 H HG   . LEU A 1 310 ? -38.821 5.52    -10.602 1 67.73   ? 310 LEU A HG   1 c 
ATOM   4744 H HD11 . LEU A 1 310 ? -37.204 6.168   -12.018 1 71.587  ? 310 LEU A HD11 1 c 
ATOM   4745 H HD12 . LEU A 1 310 ? -36.374 5.936   -10.687 1 71.523  ? 310 LEU A HD12 1 c 
ATOM   4746 H HD13 . LEU A 1 310 ? -36.78  7.406   -11.121 1 71.607  ? 310 LEU A HD13 1 c 
ATOM   4747 H HD21 . LEU A 1 310 ? -38.921 6.151   -8.349  1 64.811  ? 310 LEU A HD21 1 c 
ATOM   4748 H HD22 . LEU A 1 310 ? -37.67  7.11    -8.532  1 64.825  ? 310 LEU A HD22 1 c 
ATOM   4749 H HD23 . LEU A 1 310 ? -37.487 5.538   -8.639  1 64.778  ? 310 LEU A HD23 1 c 
ATOM   4750 N N    . LEU A 1 311 ? -42.077 7.572   -11.924 1 61.088  ? 311 LEU A N    1 ? 
ATOM   4751 C CA   . LEU A 1 311 ? -43.368 7.072   -12.353 1 59.023  ? 311 LEU A CA   1 ? 
ATOM   4752 C C    . LEU A 1 311 ? -43.581 7.326   -13.841 1 58.593  ? 311 LEU A C    1 ? 
ATOM   4753 O O    . LEU A 1 311 ? -44.036 6.437   -14.547 1 63.173  ? 311 LEU A O    1 ? 
ATOM   4754 C CB   . LEU A 1 311 ? -44.463 7.698   -11.502 1 54.156  ? 311 LEU A CB   1 ? 
ATOM   4755 C CG   . LEU A 1 311 ? -44.579 7.132   -10.087 1 58.992  ? 311 LEU A CG   1 ? 
ATOM   4756 C CD1  . LEU A 1 311 ? -45.657 7.864   -9.299  1 63.858  ? 311 LEU A CD1  1 ? 
ATOM   4757 C CD2  . LEU A 1 311 ? -44.876 5.631   -10.124 1 55.93   ? 311 LEU A CD2  1 ? 
ATOM   4758 H H    . LEU A 1 311 ? -42.043 8.187   -11.248 1 62.622  ? 311 LEU A H    1 c 
ATOM   4759 H HA   . LEU A 1 311 ? -43.37  6.093   -12.216 1 58.424  ? 311 LEU A HA   1 c 
ATOM   4760 H HB2  . LEU A 1 311 ? -44.296 8.666   -11.44  1 56.383  ? 311 LEU A HB2  1 c 
ATOM   4761 H HB3  . LEU A 1 311 ? -45.325 7.568   -11.961 1 56.341  ? 311 LEU A HB3  1 c 
ATOM   4762 H HG   . LEU A 1 311 ? -43.712 7.266   -9.626  1 58.342  ? 311 LEU A HG   1 c 
ATOM   4763 H HD11 . LEU A 1 311 ? -45.481 8.82    -9.318  1 62.382  ? 311 LEU A HD11 1 c 
ATOM   4764 H HD12 . LEU A 1 311 ? -45.654 7.553   -8.378  1 62.377  ? 311 LEU A HD12 1 c 
ATOM   4765 H HD13 . LEU A 1 311 ? -46.527 7.688   -9.696  1 62.382  ? 311 LEU A HD13 1 c 
ATOM   4766 H HD21 . LEU A 1 311 ? -44.046 5.137   -10.235 1 56.832  ? 311 LEU A HD21 1 c 
ATOM   4767 H HD22 . LEU A 1 311 ? -45.471 5.434   -10.868 1 56.81   ? 311 LEU A HD22 1 c 
ATOM   4768 H HD23 . LEU A 1 311 ? -45.3   5.362   -9.293  1 56.863  ? 311 LEU A HD23 1 c 
ATOM   4769 N N    . LYS A 1 312 ? -43.222 8.518   -14.32  1 62.374  ? 312 LYS A N    1 ? 
ATOM   4770 C CA   . LYS A 1 312 ? -43.479 8.904   -15.702 1 70.441  ? 312 LYS A CA   1 ? 
ATOM   4771 C C    . LYS A 1 312 ? -42.722 8.012   -16.691 1 64.331  ? 312 LYS A C    1 ? 
ATOM   4772 O O    . LYS A 1 312 ? -43.222 7.776   -17.793 1 59.249  ? 312 LYS A O    1 ? 
ATOM   4773 C CB   . LYS A 1 312 ? -43.157 10.396  -15.853 1 76.147  ? 312 LYS A CB   1 ? 
ATOM   4774 C CG   . LYS A 1 312 ? -43.406 11.047  -17.202 1 81.925  ? 312 LYS A CG   1 ? 
ATOM   4775 C CD   . LYS A 1 312 ? -43.392 12.579  -17.134 1 80.862  ? 312 LYS A CD   1 ? 
ATOM   4776 C CE   . LYS A 1 312 ? -43.065 13.258  -18.44  1 78.384  ? 312 LYS A CE   1 ? 
ATOM   4777 N NZ   . LYS A 1 312 ? -43.711 12.658  -19.619 1 78.269  ? 312 LYS A NZ   1 ? 
ATOM   4778 H H    . LYS A 1 312 ? -42.81  9.119   -13.767 1 63.236  ? 312 LYS A H    1 c 
ATOM   4779 H HA   . LYS A 1 312 ? -44.445 8.786   -15.872 1 68.572  ? 312 LYS A HA   1 c 
ATOM   4780 H HB2  . LYS A 1 312 ? -43.68  10.885  -15.183 1 76.107  ? 312 LYS A HB2  1 c 
ATOM   4781 H HB3  . LYS A 1 312 ? -42.21  10.523  -15.629 1 76.087  ? 312 LYS A HB3  1 c 
ATOM   4782 H HG2  . LYS A 1 312 ? -42.714 10.745  -17.83  1 80.325  ? 312 LYS A HG2  1 c 
ATOM   4783 H HG3  . LYS A 1 312 ? -44.277 10.747  -17.541 1 80.325  ? 312 LYS A HG3  1 c 
ATOM   4784 H HD2  . LYS A 1 312 ? -44.274 12.887  -16.83  1 80.516  ? 312 LYS A HD2  1 c 
ATOM   4785 H HD3  . LYS A 1 312 ? -42.734 12.858  -16.46  1 80.496  ? 312 LYS A HD3  1 c 
ATOM   4786 H HE2  . LYS A 1 312 ? -43.332 14.193  -18.383 1 78.916  ? 312 LYS A HE2  1 c 
ATOM   4787 H HE3  . LYS A 1 312 ? -42.1   13.235  -18.571 1 78.916  ? 312 LYS A HE3  1 c 
ATOM   4788 H HZ1  . LYS A 1 312 ? -44.56  12.413  -19.419 1 78.339  ? 312 LYS A HZ1  1 c 
ATOM   4789 H HZ2  . LYS A 1 312 ? -43.245 11.931  -19.892 1 78.328  ? 312 LYS A HZ2  1 c 
ATOM   4790 H HZ3  . LYS A 1 312 ? -43.731 13.264  -20.292 1 78.315  ? 312 LYS A HZ3  1 c 
ATOM   4791 N N    . GLN A 1 313 ? -41.53  7.532   -16.295 1 59.684  ? 313 GLN A N    1 ? 
ATOM   4792 C CA   . GLN A 1 313 ? -40.723 6.639   -17.12  1 58.152  ? 313 GLN A CA   1 ? 
ATOM   4793 C C    . GLN A 1 313 ? -41.144 5.175   -16.952 1 51.741  ? 313 GLN A C    1 ? 
ATOM   4794 O O    . GLN A 1 313 ? -41.323 4.469   -17.946 1 50.693  ? 313 GLN A O    1 ? 
ATOM   4795 C CB   . GLN A 1 313 ? -39.229 6.835   -16.877 1 61.102  ? 313 GLN A CB   1 ? 
ATOM   4796 C CG   . GLN A 1 313 ? -38.685 8.12    -17.496 1 61.843  ? 313 GLN A CG   1 ? 
ATOM   4797 C CD   . GLN A 1 313 ? -37.202 8.329   -17.284 1 65.568  ? 313 GLN A CD   1 ? 
ATOM   4798 O OE1  . GLN A 1 313 ? -36.441 7.394   -17.018 1 63.387  ? 313 GLN A OE1  1 ? 
ATOM   4799 N NE2  . GLN A 1 313 ? -36.768 9.574   -17.399 1 67.961  ? 313 GLN A NE2  1 ? 
ATOM   4800 H H    . GLN A 1 313 ? -41.196 7.785   -15.483 1 60.475  ? 313 GLN A H    1 c 
ATOM   4801 H HA   . GLN A 1 313 ? -40.879 6.883   -18.068 1 57.785  ? 313 GLN A HA   1 c 
ATOM   4802 H HB2  . GLN A 1 313 ? -39.063 6.85    -15.911 1 60.576  ? 313 GLN A HB2  1 c 
ATOM   4803 H HB3  . GLN A 1 313 ? -38.744 6.07    -17.252 1 60.545  ? 313 GLN A HB3  1 c 
ATOM   4804 H HG2  . GLN A 1 313 ? -38.869 8.118   -18.458 1 62.476  ? 313 GLN A HG2  1 c 
ATOM   4805 H HG3  . GLN A 1 313 ? -39.161 8.885   -17.109 1 62.506  ? 313 GLN A HG3  1 c 
ATOM   4806 H HE21 . GLN A 1 313 ? -36.148 9.879   -16.843 1 67.206  ? 313 GLN A HE21 1 c 
ATOM   4807 H HE22 . GLN A 1 313 ? -37.098 10.101  -18.032 1 67.178  ? 313 GLN A HE22 1 c 
ATOM   4808 N N    . GLU A 1 314 ? -41.358 4.736   -15.712 1 52.124  ? 314 GLU A N    1 ? 
ATOM   4809 C CA   . GLU A 1 314 ? -41.619 3.334   -15.423 1 55.988  ? 314 GLU A CA   1 ? 
ATOM   4810 C C    . GLU A 1 314 ? -43.037 2.924   -15.817 1 55.588  ? 314 GLU A C    1 ? 
ATOM   4811 O O    . GLU A 1 314 ? -43.213 1.867   -16.427 1 54.277  ? 314 GLU A O    1 ? 
ATOM   4812 C CB   . GLU A 1 314 ? -41.325 3.015   -13.957 1 52.274  ? 314 GLU A CB   1 ? 
ATOM   4813 C CG   . GLU A 1 314 ? -39.833 3.078   -13.663 1 52.212  ? 314 GLU A CG   1 ? 
ATOM   4814 C CD   . GLU A 1 314 ? -39.403 2.757   -12.241 1 56.003  ? 314 GLU A CD   1 ? 
ATOM   4815 O OE1  . GLU A 1 314 ? -40.282 2.566   -11.371 1 58.435  ? 314 GLU A OE1  1 ? 
ATOM   4816 O OE2  . GLU A 1 314 ? -38.165 2.703   -12.025 1 53.267  ? 314 GLU A OE2  1 ? 
ATOM   4817 H H    . GLU A 1 314 ? -41.336 5.329   -15.017 1 52.951  ? 314 GLU A H    1 c 
ATOM   4818 H HA   . GLU A 1 314 ? -40.989 2.792   -15.965 1 54.39   ? 314 GLU A HA   1 c 
ATOM   4819 H HB2  . GLU A 1 314 ? -41.802 3.656   -13.388 1 53.082  ? 314 GLU A HB2  1 c 
ATOM   4820 H HB3  . GLU A 1 314 ? -41.663 2.119   -13.749 1 53.093  ? 314 GLU A HB3  1 c 
ATOM   4821 H HG2  . GLU A 1 314 ? -39.371 2.457   -14.266 1 53.007  ? 314 GLU A HG2  1 c 
ATOM   4822 H HG3  . GLU A 1 314 ? -39.509 3.978   -13.881 1 53.086  ? 314 GLU A HG3  1 c 
ATOM   4823 N N    . LEU A 1 315 ? -44.04  3.733   -15.456 1 54.43   ? 315 LEU A N    1 ? 
ATOM   4824 C CA   . LEU A 1 315 ? -45.439 3.341   -15.626 1 50.488  ? 315 LEU A CA   1 ? 
ATOM   4825 C C    . LEU A 1 315 ? -45.717 2.858   -17.051 1 51.281  ? 315 LEU A C    1 ? 
ATOM   4826 O O    . LEU A 1 315 ? -46.306 1.795   -17.213 1 52.433  ? 315 LEU A O    1 ? 
ATOM   4827 C CB   . LEU A 1 315 ? -46.413 4.445   -15.218 1 50.757  ? 315 LEU A CB   1 ? 
ATOM   4828 C CG   . LEU A 1 315 ? -46.666 4.587   -13.714 1 53.215  ? 315 LEU A CG   1 ? 
ATOM   4829 C CD1  . LEU A 1 315 ? -47.55  5.78    -13.428 1 58.392  ? 315 LEU A CD1  1 ? 
ATOM   4830 C CD2  . LEU A 1 315 ? -47.313 3.351   -13.131 1 53.427  ? 315 LEU A CD2  1 ? 
ATOM   4831 H H    . LEU A 1 315 ? -43.853 4.548   -15.087 1 53.755  ? 315 LEU A H    1 c 
ATOM   4832 H HA   . LEU A 1 315 ? -45.587 2.564   -15.035 1 51.458  ? 315 LEU A HA   1 c 
ATOM   4833 H HB2  . LEU A 1 315 ? -46.073 5.303   -15.559 1 51.384  ? 315 LEU A HB2  1 c 
ATOM   4834 H HB3  . LEU A 1 315 ? -47.276 4.274   -15.66  1 51.271  ? 315 LEU A HB3  1 c 
ATOM   4835 H HG   . LEU A 1 315 ? -45.794 4.727   -13.261 1 53.718  ? 315 LEU A HG   1 c 
ATOM   4836 H HD11 . LEU A 1 315 ? -47.178 6.57    -13.855 1 56.761  ? 315 LEU A HD11 1 c 
ATOM   4837 H HD12 . LEU A 1 315 ? -47.6   5.925   -12.468 1 56.772  ? 315 LEU A HD12 1 c 
ATOM   4838 H HD13 . LEU A 1 315 ? -48.442 5.614   -13.776 1 56.79   ? 315 LEU A HD13 1 c 
ATOM   4839 H HD21 . LEU A 1 315 ? -46.667 2.628   -13.091 1 53.342  ? 315 LEU A HD21 1 c 
ATOM   4840 H HD22 . LEU A 1 315 ? -48.06  3.089   -13.692 1 53.29   ? 315 LEU A HD22 1 c 
ATOM   4841 H HD23 . LEU A 1 315 ? -47.636 3.544   -12.234 1 53.392  ? 315 LEU A HD23 1 c 
ATOM   4842 N N    . PRO A 1 316 ? -45.372 3.611   -18.123 1 52.455  ? 316 PRO A N    1 ? 
ATOM   4843 C CA   . PRO A 1 316 ? -45.601 3.129   -19.484 1 53.847  ? 316 PRO A CA   1 ? 
ATOM   4844 C C    . PRO A 1 316 ? -44.819 1.87    -19.882 1 47.635  ? 316 PRO A C    1 ? 
ATOM   4845 O O    . PRO A 1 316 ? -45.337 1.066   -20.654 1 48.007  ? 316 PRO A O    1 ? 
ATOM   4846 C CB   . PRO A 1 316 ? -45.297 4.344   -20.367 1 51.335  ? 316 PRO A CB   1 ? 
ATOM   4847 C CG   . PRO A 1 316 ? -44.469 5.251   -19.479 1 51.59   ? 316 PRO A CG   1 ? 
ATOM   4848 C CD   . PRO A 1 316 ? -44.949 5.02    -18.093 1 54.959  ? 316 PRO A CD   1 ? 
ATOM   4849 H HA   . PRO A 1 316 ? -46.557 2.933   -19.579 1 51.924  ? 316 PRO A HA   1 c 
ATOM   4850 H HB2  . PRO A 1 316 ? -44.793 4.082   -21.162 1 51.918  ? 316 PRO A HB2  1 c 
ATOM   4851 H HB3  . PRO A 1 316 ? -46.119 4.787   -20.648 1 51.939  ? 316 PRO A HB3  1 c 
ATOM   4852 H HG2  . PRO A 1 316 ? -43.519 5.032   -19.552 1 52.293  ? 316 PRO A HG2  1 c 
ATOM   4853 H HG3  . PRO A 1 316 ? -44.594 6.188   -19.731 1 52.293  ? 316 PRO A HG3  1 c 
ATOM   4854 H HD2  . PRO A 1 316 ? -44.233 5.159   -17.448 1 53.576  ? 316 PRO A HD2  1 c 
ATOM   4855 H HD3  . PRO A 1 316 ? -45.701 5.603   -17.875 1 53.573  ? 316 PRO A HD3  1 c 
ATOM   4856 N N    . LEU A 1 317 ? -43.59  1.696   -19.392 1 45.4    ? 317 LEU A N    1 ? 
ATOM   4857 C CA   . LEU A 1 317 ? -42.807 0.511   -19.726 1 48.344  ? 317 LEU A CA   1 ? 
ATOM   4858 C C    . LEU A 1 317 ? -43.401 -0.728  -19.067 1 49.787  ? 317 LEU A C    1 ? 
ATOM   4859 O O    . LEU A 1 317 ? -43.541 -1.749  -19.728 1 47.679  ? 317 LEU A O    1 ? 
ATOM   4860 C CB   . LEU A 1 317 ? -41.355 0.72    -19.326 1 53.001  ? 317 LEU A CB   1 ? 
ATOM   4861 C CG   . LEU A 1 317 ? -40.67  1.881   -20.04  1 46.783  ? 317 LEU A CG   1 ? 
ATOM   4862 C CD1  . LEU A 1 317 ? -39.227 1.95    -19.681 1 46.497  ? 317 LEU A CD1  1 ? 
ATOM   4863 C CD2  . LEU A 1 317 ? -40.853 1.739   -21.532 1 55.213  ? 317 LEU A CD2  1 ? 
ATOM   4864 H H    . LEU A 1 317 ? -43.229 2.325   -18.837 1 46.715  ? 317 LEU A H    1 c 
ATOM   4865 H HA   . LEU A 1 317 ? -42.855 0.377   -20.705 1 48.889  ? 317 LEU A HA   1 c 
ATOM   4866 H HB2  . LEU A 1 317 ? -41.321 0.883   -18.355 1 50.446  ? 317 LEU A HB2  1 c 
ATOM   4867 H HB3  . LEU A 1 317 ? -40.857 -0.107  -19.521 1 50.446  ? 317 LEU A HB3  1 c 
ATOM   4868 H HG   . LEU A 1 317 ? -41.103 2.724   -19.756 1 49.287  ? 317 LEU A HG   1 c 
ATOM   4869 H HD11 . LEU A 1 317 ? -39.134 1.97    -18.714 1 46.581  ? 317 LEU A HD11 1 c 
ATOM   4870 H HD12 . LEU A 1 317 ? -38.836 2.755   -20.06  1 46.618  ? 317 LEU A HD12 1 c 
ATOM   4871 H HD13 . LEU A 1 317 ? -38.767 1.171   -20.034 1 46.589  ? 317 LEU A HD13 1 c 
ATOM   4872 H HD21 . LEU A 1 317 ? -41.718 2.099   -21.791 1 52.483  ? 317 LEU A HD21 1 c 
ATOM   4873 H HD22 . LEU A 1 317 ? -40.805 0.8     -21.78  1 52.488  ? 317 LEU A HD22 1 c 
ATOM   4874 H HD23 . LEU A 1 317 ? -40.151 2.229   -21.993 1 52.461  ? 317 LEU A HD23 1 c 
ATOM   4875 N N    . ILE A 1 318 ? -43.841 -0.592  -17.808 1 49.965  ? 318 ILE A N    1 ? 
ATOM   4876 C CA   . ILE A 1 318 ? -44.573 -1.648  -17.131 1 48.298  ? 318 ILE A CA   1 ? 
ATOM   4877 C C    . ILE A 1 318 ? -45.779 -2.07   -17.976 1 50.086  ? 318 ILE A C    1 ? 
ATOM   4878 O O    . ILE A 1 318 ? -45.948 -3.26   -18.247 1 49.742  ? 318 ILE A O    1 ? 
ATOM   4879 C CB   . ILE A 1 318 ? -44.946 -1.243  -15.691 1 44.809  ? 318 ILE A CB   1 ? 
ATOM   4880 C CG1  . ILE A 1 318 ? -43.682 -1.103  -14.827 1 48.124  ? 318 ILE A CG1  1 ? 
ATOM   4881 C CG2  . ILE A 1 318 ? -45.959 -2.23   -15.092 1 41.409  ? 318 ILE A CG2  1 ? 
ATOM   4882 C CD1  . ILE A 1 318 ? -43.916 -0.727  -13.367 1 46.617  ? 318 ILE A CD1  1 ? 
ATOM   4883 H H    . ILE A 1 318 ? -43.676 0.186   -17.358 1 49.445  ? 318 ILE A H    1 c 
ATOM   4884 H HA   . ILE A 1 318 ? -43.976 -2.419  -17.069 1 48.276  ? 318 ILE A HA   1 c 
ATOM   4885 H HB   . ILE A 1 318 ? -45.374 -0.365  -15.732 1 45.372  ? 318 ILE A HB   1 c 
ATOM   4886 H HG12 . ILE A 1 318 ? -43.198 -1.954  -14.851 1 47.026  ? 318 ILE A HG12 1 c 
ATOM   4887 H HG13 . ILE A 1 318 ? -43.104 -0.426  -15.228 1 47.072  ? 318 ILE A HG13 1 c 
ATOM   4888 H HG21 . ILE A 1 318 ? -45.971 -2.146  -14.125 1 42.452  ? 318 ILE A HG21 1 c 
ATOM   4889 H HG22 . ILE A 1 318 ? -45.709 -3.139  -15.331 1 42.462  ? 318 ILE A HG22 1 c 
ATOM   4890 H HG23 . ILE A 1 318 ? -46.847 -2.038  -15.437 1 42.44   ? 318 ILE A HG23 1 c 
ATOM   4891 H HD11 . ILE A 1 318 ? -44.691 -0.138  -13.3   1 47.079  ? 318 ILE A HD11 1 c 
ATOM   4892 H HD12 . ILE A 1 318 ? -43.128 -0.266  -13.022 1 47.08   ? 318 ILE A HD12 1 c 
ATOM   4893 H HD13 . ILE A 1 318 ? -44.075 -1.533  -12.841 1 47.033  ? 318 ILE A HD13 1 c 
ATOM   4894 N N    . ARG A 1 319 ? -46.597 -1.101  -18.409 1 49.795  ? 319 ARG A N    1 ? 
ATOM   4895 C CA   . ARG A 1 319 ? -47.818 -1.404  -19.142 1 48.259  ? 319 ARG A CA   1 ? 
ATOM   4896 C C    . ARG A 1 319 ? -47.515 -2.105  -20.467 1 47.751  ? 319 ARG A C    1 ? 
ATOM   4897 O O    . ARG A 1 319 ? -48.193 -3.062  -20.832 1 43.275  ? 319 ARG A O    1 ? 
ATOM   4898 C CB   . ARG A 1 319 ? -48.601 -0.142  -19.508 1 53.137  ? 319 ARG A CB   1 ? 
ATOM   4899 C CG   . ARG A 1 319 ? -49.876 -0.461  -20.28  1 56.071  ? 319 ARG A CG   1 ? 
ATOM   4900 C CD   . ARG A 1 319 ? -50.887 0.676   -20.314 1 57.613  ? 319 ARG A CD   1 ? 
ATOM   4901 N NE   . ARG A 1 319 ? -51.423 1.057   -19.001 1 55.906  ? 319 ARG A NE   1 ? 
ATOM   4902 C CZ   . ARG A 1 319 ? -52.598 1.641   -18.795 1 56.911  ? 319 ARG A CZ   1 ? 
ATOM   4903 N NH1  . ARG A 1 319 ? -53.397 1.908   -19.814 1 55.162  ? 319 ARG A NH1  1 ? 
ATOM   4904 N NH2  . ARG A 1 319 ? -52.98  1.937   -17.565 1 55.093  ? 319 ARG A NH2  1 ? 
ATOM   4905 H H    . ARG A 1 319 ? -46.393 -0.226  -18.236 1 49.531  ? 319 ARG A H    1 c 
ATOM   4906 H HA   . ARG A 1 319 ? -48.384 -1.996  -18.584 1 49.314  ? 319 ARG A HA   1 c 
ATOM   4907 H HB2  . ARG A 1 319 ? -48.83  0.342   -18.687 1 52.666  ? 319 ARG A HB2  1 c 
ATOM   4908 H HB3  . ARG A 1 319 ? -48.032 0.442   -20.053 1 52.621  ? 319 ARG A HB3  1 c 
ATOM   4909 H HG2  . ARG A 1 319 ? -49.642 -0.691  -21.205 1 55.685  ? 319 ARG A HG2  1 c 
ATOM   4910 H HG3  . ARG A 1 319 ? -50.302 -1.249  -19.879 1 55.689  ? 319 ARG A HG3  1 c 
ATOM   4911 H HD2  . ARG A 1 319 ? -50.457 1.454   -20.72  1 56.852  ? 319 ARG A HD2  1 c 
ATOM   4912 H HD3  . ARG A 1 319 ? -51.625 0.407   -20.898 1 56.845  ? 319 ARG A HD3  1 c 
ATOM   4913 H HE   . ARG A 1 319 ? -50.944 0.884   -18.297 1 56.462  ? 319 ARG A HE   1 c 
ATOM   4914 H HH11 . ARG A 1 319 ? -53.192 2.562   -20.372 1 55.695  ? 319 ARG A HH11 1 c 
ATOM   4915 H HH12 . ARG A 1 319 ? -54.132 1.432   -19.932 1 55.694  ? 319 ARG A HH12 1 c 
ATOM   4916 H HH21 . ARG A 1 319 ? -52.846 1.357   -16.912 1 55.653  ? 319 ARG A HH21 1 c 
ATOM   4917 H HH22 . ARG A 1 319 ? -53.369 2.714   -17.401 1 55.648  ? 319 ARG A HH22 1 c 
ATOM   4918 N N    . HIS A 1 320 ? -46.544 -1.566  -21.21  1 44.061  ? 320 HIS A N    1 ? 
ATOM   4919 C CA   . HIS A 1 320 ? -46.192 -2.074  -22.522 1 47      ? 320 HIS A CA   1 ? 
ATOM   4920 C C    . HIS A 1 320 ? -45.71  -3.535  -22.416 1 49.822  ? 320 HIS A C    1 ? 
ATOM   4921 O O    . HIS A 1 320 ? -46.254 -4.418  -23.083 1 45.441  ? 320 HIS A O    1 ? 
ATOM   4922 C CB   . HIS A 1 320 ? -45.208 -1.086  -23.155 1 47.309  ? 320 HIS A CB   1 ? 
ATOM   4923 C CG   . HIS A 1 320 ? -45.115 -1.227  -24.624 1 51.307  ? 320 HIS A CG   1 ? 
ATOM   4924 N ND1  . HIS A 1 320 ? -46.201 -0.975  -25.435 1 51.349  ? 320 HIS A ND1  1 ? 
ATOM   4925 C CD2  . HIS A 1 320 ? -44.126 -1.666  -25.415 1 52.21   ? 320 HIS A CD2  1 ? 
ATOM   4926 C CE1  . HIS A 1 320 ? -45.847 -1.21   -26.689 1 56.18   ? 320 HIS A CE1  1 ? 
ATOM   4927 N NE2  . HIS A 1 320 ? -44.589 -1.63   -26.7   1 53.69   ? 320 HIS A NE2  1 ? 
ATOM   4928 H H    . HIS A 1 320 ? -46.081 -0.85   -20.88  1 45.651  ? 320 HIS A H    1 c 
ATOM   4929 H HA   . HIS A 1 320 ? -47.02  -2.067  -23.061 1 47.017  ? 320 HIS A HA   1 c 
ATOM   4930 H HB2  . HIS A 1 320 ? -45.497 -0.173  -22.945 1 48.151  ? 320 HIS A HB2  1 c 
ATOM   4931 H HB3  . HIS A 1 320 ? -44.32  -1.227  -22.761 1 48.148  ? 320 HIS A HB3  1 c 
ATOM   4932 H HD2  . HIS A 1 320 ? -43.265 -1.919  -25.148 1 52.322  ? 320 HIS A HD2  1 c 
ATOM   4933 H HE1  . HIS A 1 320 ? -46.399 -1.099  -27.444 1 54.394  ? 320 HIS A HE1  1 c 
ATOM   4934 N N    . TYR A 1 321 ? -44.727 -3.787  -21.535 1 47.681  ? 321 TYR A N    1 ? 
ATOM   4935 C CA   . TYR A 1 321 ? -44.202 -5.121  -21.28  1 50.823  ? 321 TYR A CA   1 ? 
ATOM   4936 C C    . TYR A 1 321 ? -45.325 -6.09   -20.9   1 47.936  ? 321 TYR A C    1 ? 
ATOM   4937 O O    . TYR A 1 321 ? -45.446 -7.157  -21.498 1 42.906  ? 321 TYR A O    1 ? 
ATOM   4938 C CB   . TYR A 1 321 ? -43.134 -5.14   -20.177 1 50.347  ? 321 TYR A CB   1 ? 
ATOM   4939 C CG   . TYR A 1 321 ? -42.925 -6.504  -19.533 1 51.335  ? 321 TYR A CG   1 ? 
ATOM   4940 C CD1  . TYR A 1 321 ? -42.386 -7.576  -20.242 1 55.188  ? 321 TYR A CD1  1 ? 
ATOM   4941 C CD2  . TYR A 1 321 ? -43.25  -6.711  -18.2   1 54.424  ? 321 TYR A CD2  1 ? 
ATOM   4942 C CE1  . TYR A 1 321 ? -42.188 -8.814  -19.646 1 54.547  ? 321 TYR A CE1  1 ? 
ATOM   4943 C CE2  . TYR A 1 321 ? -43.071 -7.943  -17.594 1 55.015  ? 321 TYR A CE2  1 ? 
ATOM   4944 C CZ   . TYR A 1 321 ? -42.528 -8.993  -18.315 1 53.701  ? 321 TYR A CZ   1 ? 
ATOM   4945 O OH   . TYR A 1 321 ? -42.379 -10.193 -17.693 1 50.844  ? 321 TYR A OH   1 ? 
ATOM   4946 H H    . TYR A 1 321 ? -44.362 -3.085  -21.077 1 48.863  ? 321 TYR A H    1 c 
ATOM   4947 H HA   . TYR A 1 321 ? -43.786 -5.452  -22.118 1 49.646  ? 321 TYR A HA   1 c 
ATOM   4948 H HB2  . TYR A 1 321 ? -42.289 -4.831  -20.543 1 51.015  ? 321 TYR A HB2  1 c 
ATOM   4949 H HB3  . TYR A 1 321 ? -43.401 -4.501  -19.48  1 50.77   ? 321 TYR A HB3  1 c 
ATOM   4950 H HD1  . TYR A 1 321 ? -42.148 -7.458  -21.148 1 54.098  ? 321 TYR A HD1  1 c 
ATOM   4951 H HD2  . TYR A 1 321 ? -43.619 -6.002  -17.698 1 53.789  ? 321 TYR A HD2  1 c 
ATOM   4952 H HE1  . TYR A 1 321 ? -41.831 -9.53   -20.143 1 54.375  ? 321 TYR A HE1  1 c 
ATOM   4953 H HE2  . TYR A 1 321 ? -43.305 -8.064  -16.69  1 54.517  ? 321 TYR A HE2  1 c 
ATOM   4954 N N    . LEU A 1 322 ? -46.155 -5.725  -19.922 1 47.335  ? 322 LEU A N    1 ? 
ATOM   4955 C CA   . LEU A 1 322 ? -47.186 -6.644  -19.444 1 46.402  ? 322 LEU A CA   1 ? 
ATOM   4956 C C    . LEU A 1 322 ? -48.229 -6.914  -20.529 1 44.991  ? 322 LEU A C    1 ? 
ATOM   4957 O O    . LEU A 1 322 ? -48.972 -7.88   -20.397 1 43.606  ? 322 LEU A O    1 ? 
ATOM   4958 C CB   . LEU A 1 322 ? -47.863 -6.195  -18.144 1 45.405  ? 322 LEU A CB   1 ? 
ATOM   4959 C CG   . LEU A 1 322 ? -46.991 -6.174  -16.886 1 47.596  ? 322 LEU A CG   1 ? 
ATOM   4960 C CD1  . LEU A 1 322 ? -47.683 -5.481  -15.738 1 48.752  ? 322 LEU A CD1  1 ? 
ATOM   4961 C CD2  . LEU A 1 322 ? -46.603 -7.576  -16.476 1 51.127  ? 322 LEU A CD2  1 ? 
ATOM   4962 H H    . LEU A 1 322 ? -46.081 -4.898  -19.539 1 47.292  ? 322 LEU A H    1 c 
ATOM   4963 H HA   . LEU A 1 322 ? -46.738 -7.509  -19.266 1 46.168  ? 322 LEU A HA   1 c 
ATOM   4964 H HB2  . LEU A 1 322 ? -48.223 -5.289  -18.285 1 46.137  ? 322 LEU A HB2  1 c 
ATOM   4965 H HB3  . LEU A 1 322 ? -48.632 -6.788  -17.976 1 46.129  ? 322 LEU A HB3  1 c 
ATOM   4966 H HG   . LEU A 1 322 ? -46.161 -5.674  -17.093 1 48.046  ? 322 LEU A HG   1 c 
ATOM   4967 H HD11 . LEU A 1 322 ? -47.963 -4.593  -16.016 1 48.392  ? 322 LEU A HD11 1 c 
ATOM   4968 H HD12 . LEU A 1 322 ? -47.07  -5.406  -14.987 1 48.412  ? 322 LEU A HD12 1 c 
ATOM   4969 H HD13 . LEU A 1 322 ? -48.462 -5.997  -15.469 1 48.404  ? 322 LEU A HD13 1 c 
ATOM   4970 H HD21 . LEU A 1 322 ? -45.941 -7.925  -17.097 1 50.013  ? 322 LEU A HD21 1 c 
ATOM   4971 H HD22 . LEU A 1 322 ? -47.389 -8.148  -16.488 1 50.013  ? 322 LEU A HD22 1 c 
ATOM   4972 H HD23 . LEU A 1 322 ? -46.227 -7.562  -15.58  1 50.02   ? 322 LEU A HD23 1 c 
ATOM   4973 N N    . ASN A 1 323 ? -48.318 -6.091  -21.587 1 46.384  ? 323 ASN A N    1 ? 
ATOM   4974 C CA   . ASN A 1 323 ? -49.326 -6.347  -22.606 1 51.761  ? 323 ASN A CA   1 ? 
ATOM   4975 C C    . ASN A 1 323 ? -48.733 -6.977  -23.868 1 52.775  ? 323 ASN A C    1 ? 
ATOM   4976 O O    . ASN A 1 323 ? -49.499 -7.354  -24.756 1 54.787  ? 323 ASN A O    1 ? 
ATOM   4977 C CB   . ASN A 1 323 ? -50.151 -5.094  -22.884 1 55.872  ? 323 ASN A CB   1 ? 
ATOM   4978 C CG   . ASN A 1 323 ? -51.147 -4.826  -21.775 1 60.566  ? 323 ASN A CG   1 ? 
ATOM   4979 O OD1  . ASN A 1 323 ? -52.042 -5.642  -21.517 1 70.279  ? 323 ASN A OD1  1 ? 
ATOM   4980 N ND2  . ASN A 1 323 ? -51.018 -3.693  -21.107 1 55.23   ? 323 ASN A ND2  1 ? 
ATOM   4981 H H    . ASN A 1 323 ? -47.794 -5.346  -21.656 1 47.235  ? 323 ASN A H    1 c 
ATOM   4982 H HA   . ASN A 1 323 ? -49.954 -7.01   -22.245 1 51.622  ? 323 ASN A HA   1 c 
ATOM   4983 H HB2  . ASN A 1 323 ? -49.551 -4.327  -22.973 1 55.927  ? 323 ASN A HB2  1 c 
ATOM   4984 H HB3  . ASN A 1 323 ? -50.633 -5.203  -23.728 1 55.914  ? 323 ASN A HB3  1 c 
ATOM   4985 H HD21 . ASN A 1 323 ? -51.723 -3.17   -20.981 1 56.818  ? 323 ASN A HD21 1 c 
ATOM   4986 H HD22 . ASN A 1 323 ? -50.225 -3.457  -20.787 1 56.811  ? 323 ASN A HD22 1 c 
ATOM   4987 N N    . LEU A 1 324 ? -47.399 -7.081  -23.971 1 49.092  ? 324 LEU A N    1 ? 
ATOM   4988 C CA   . LEU A 1 324 ? -46.777 -7.677  -25.144 1 48.598  ? 324 LEU A CA   1 ? 
ATOM   4989 C C    . LEU A 1 324 ? -46.99  -9.212  -25.151 1 52.465  ? 324 LEU A C    1 ? 
ATOM   4990 O O    . LEU A 1 324 ? -47.439 -9.755  -24.11  1 45.585  ? 324 LEU A O    1 ? 
ATOM   4991 C CB   . LEU A 1 324 ? -45.298 -7.301  -25.218 1 49.557  ? 324 LEU A CB   1 ? 
ATOM   4992 C CG   . LEU A 1 324 ? -44.972 -5.933  -25.834 1 48.808  ? 324 LEU A CG   1 ? 
ATOM   4993 C CD1  . LEU A 1 324 ? -43.489 -5.656  -25.728 1 49.903  ? 324 LEU A CD1  1 ? 
ATOM   4994 C CD2  . LEU A 1 324 ? -45.427 -5.872  -27.294 1 50.764  ? 324 LEU A CD2  1 ? 
ATOM   4995 O OXT  . LEU A 1 324 ? -46.742 -9.819  -26.229 1 58.83   ? 324 LEU A OXT  1 ? 
ATOM   4996 H H    . LEU A 1 324 ? -46.864 -6.773  -23.298 1 49.78   ? 324 LEU A H    1 c 
ATOM   4997 H HA   . LEU A 1 324 ? -47.233 -7.313  -25.943 1 49.607  ? 324 LEU A HA   1 c 
ATOM   4998 H HB2  . LEU A 1 324 ? -44.925 -7.329  -24.307 1 49.187  ? 324 LEU A HB2  1 c 
ATOM   4999 H HB3  . LEU A 1 324 ? -44.83  -7.992  -25.741 1 49.237  ? 324 LEU A HB3  1 c 
ATOM   5000 H HG   . LEU A 1 324 ? -45.459 -5.236  -25.328 1 49.483  ? 324 LEU A HG   1 c 
ATOM   5001 H HD11 . LEU A 1 324 ? -43.207 -5.741  -24.801 1 49.574  ? 324 LEU A HD11 1 c 
ATOM   5002 H HD12 . LEU A 1 324 ? -43.303 -4.755  -26.041 1 49.579  ? 324 LEU A HD12 1 c 
ATOM   5003 H HD13 . LEU A 1 324 ? -42.999 -6.295  -26.274 1 49.576  ? 324 LEU A HD13 1 c 
ATOM   5004 H HD21 . LEU A 1 324 ? -46.351 -5.573  -27.334 1 50.181  ? 324 LEU A HD21 1 c 
ATOM   5005 H HD22 . LEU A 1 324 ? -45.357 -6.754  -27.696 1 50.177  ? 324 LEU A HD22 1 c 
ATOM   5006 H HD23 . LEU A 1 324 ? -44.867 -5.25   -27.785 1 50.202  ? 324 LEU A HD23 1 c 
HETATM 5007 C C1   . NGT B 2 .   ? -26.457 -6.085  -13.913 1 57.441  ? 401 NGT A C1   1 ? 
HETATM 5008 C C2   . NGT B 2 .   ? -26.036 -6.244  -12.445 1 58.254  ? 401 NGT A C2   1 ? 
HETATM 5009 C C3   . NGT B 2 .   ? -26.756 -5.164  -11.662 1 58.19   ? 401 NGT A C3   1 ? 
HETATM 5010 C C4   . NGT B 2 .   ? -26.492 -3.791  -12.267 1 62.892  ? 401 NGT A C4   1 ? 
HETATM 5011 C C5   . NGT B 2 .   ? -26.801 -3.677  -13.767 1 71.366  ? 401 NGT A C5   1 ? 
HETATM 5012 C C6   . NGT B 2 .   ? -25.628 -3.233  -14.616 1 77.239  ? 401 NGT A C6   1 ? 
HETATM 5013 C C7   . NGT B 2 .   ? -27.272 -8.17   -12.483 1 49.648  ? 401 NGT A C7   1 ? 
HETATM 5014 C C8   . NGT B 2 .   ? -28.021 -9.397  -12.071 1 43.666  ? 401 NGT A C8   1 ? 
HETATM 5015 N N2   . NGT B 2 .   ? -26.372 -7.562  -11.833 1 48.372  ? 401 NGT A N2   1 ? 
HETATM 5016 S S1   . NGT B 2 .   ? -27.583 -7.472  -14.005 1 57.056  ? 401 NGT A S1   1 ? 
HETATM 5017 O O3   . NGT B 2 .   ? -26.289 -5.222  -10.313 1 52.658  ? 401 NGT A O3   1 ? 
HETATM 5018 O O4   . NGT B 2 .   ? -27.327 -2.865  -11.58  1 63.797  ? 401 NGT A O4   1 ? 
HETATM 5019 O O5   . NGT B 2 .   ? -27.222 -4.956  -14.281 1 76.494  ? 401 NGT A O5   1 ? 
HETATM 5020 O O6   . NGT B 2 .   ? -25.647 -1.823  -14.878 1 73.705  ? 401 NGT A O6   1 ? 
HETATM 5021 H HC1  . NGT B 2 .   ? -25.696 -6.207  -14.527 1 61.028  ? 401 NGT A HC1  1 c 
HETATM 5022 H HC2  . NGT B 2 .   ? -25.057 -6.108  -12.365 1 56.062  ? 401 NGT A HC2  1 c 
HETATM 5023 H HC3  . NGT B 2 .   ? -27.731 -5.348  -11.674 1 57.966  ? 401 NGT A HC3  1 c 
HETATM 5024 H HC4  . NGT B 2 .   ? -25.548 -3.547  -12.099 1 63.745  ? 401 NGT A HC4  1 c 
HETATM 5025 H HC5  . NGT B 2 .   ? -27.543 -3.034  -13.891 1 71.697  ? 401 NGT A HC5  1 c 
HETATM 5026 H HC61 . NGT B 2 .   ? -25.647 -3.711  -15.472 1 75.012  ? 401 NGT A HC61 1 c 
HETATM 5027 H HC62 . NGT B 2 .   ? -24.789 -3.461  -14.166 1 74.873  ? 401 NGT A HC62 1 c 
HETATM 5028 O O    . HOH C 3 .   ? -26.638 -7.509  -0.645  1 51.21   ? 501 HOH A O    1 ? 
HETATM 5029 O O    . HOH C 3 .   ? -35.377 -8.471  -16.34  1 41.877  ? 502 HOH A O    1 ? 
HETATM 5030 O O    . HOH C 3 .   ? -10.705 -24.002 -9.75   1 49.067  ? 503 HOH A O    1 ? 
HETATM 5031 O O    . HOH C 3 .   ? -31.253 -6.805  -3.724  1 54.364  ? 504 HOH A O    1 ? 
HETATM 5032 O O    . HOH C 3 .   ? -36.314 -10.814 -25.298 1 41.355  ? 505 HOH A O    1 ? 
HETATM 5033 O O    . HOH C 3 .   ? -30.027 -10.158 -6.5    1 47.349  ? 506 HOH A O    1 ? 
HETATM 5034 O O    . HOH C 3 .   ? -39.317 -15.201 -10.338 1 39.495  ? 507 HOH A O    1 ? 
HETATM 5035 O O    . HOH C 3 .   ? -42.775 -21.579 -2.877  1 59.142  ? 508 HOH A O    1 ? 
HETATM 5036 O O    . HOH C 3 .   ? -38.206 -13.362 -8.883  1 42.987  ? 509 HOH A O    1 ? 
HETATM 5037 O O    . HOH C 3 .   ? -31.198 3.842   -13.485 1 50.189  ? 510 HOH A O    1 ? 
HETATM 5038 O O    . HOH C 3 .   ? -27.123 -6.796  -8.379  1 47.068  ? 511 HOH A O    1 ? 
HETATM 5039 O O    . HOH C 3 .   ? -26.784 -4.221  0.978   1 54.189  ? 512 HOH A O    1 ? 
HETATM 5040 O O    . HOH C 3 .   ? -15.957 -23.236 -12.46  1 49.662  ? 513 HOH A O    1 ? 
HETATM 5041 O O    . HOH C 3 .   ? -43.301 -14.42  -19.231 1 51.721  ? 514 HOH A O    1 ? 
HETATM 5042 O O    . HOH C 3 .   ? -18.432 -17.897 -11.815 1 43.049  ? 515 HOH A O    1 ? 
HETATM 5043 O O    . HOH C 3 .   ? -32.333 -13.963 -20.889 1 46.318  ? 516 HOH A O    1 ? 
HETATM 5044 O O    . HOH C 3 .   ? -34.687 1.192   -9.766  1 48.442  ? 517 HOH A O    1 ? 
HETATM 5045 O O    . HOH C 3 .   ? -20.584 -18.99  -15.68  1 50.768  ? 518 HOH A O    1 ? 
HETATM 5046 O O    . HOH C 3 .   ? -35.652 -20.226 8.07    1 59.327  ? 519 HOH A O    1 ? 
HETATM 5047 O O    . HOH C 3 .   ? -38.832 5.606   4.488   1 71.281  ? 520 HOH A O    1 ? 
HETATM 5048 O O    . HOH C 3 .   ? -50.928 -12.673 2.219   1 69.65   ? 521 HOH A O    1 ? 
HETATM 5049 O O    . HOH C 3 .   ? -35.86  -2.306  14.492  1 69.998  ? 522 HOH A O    1 ? 
HETATM 5050 O O    . HOH C 3 .   ? -19.73  -23.419 -17.499 1 44.728  ? 523 HOH A O    1 ? 
HETATM 5051 O O    . HOH C 3 .   ? -41.911 -16.485 6.649   1 69.014  ? 524 HOH A O    1 ? 
HETATM 5052 O O    . HOH C 3 .   ? -24.919 -17.205 -10.468 1 47.59   ? 525 HOH A O    1 ? 
HETATM 5053 O O    . HOH C 3 .   ? -42.214 -14.418 -1.824  1 50.004  ? 526 HOH A O    1 ? 
HETATM 5054 O O    . HOH C 3 .   ? -41.484 -16.301 -20.276 1 60.451  ? 527 HOH A O    1 ? 
HETATM 5055 O O    . HOH C 3 .   ? -23.674 -11.912 -5.574  1 46.092  ? 528 HOH A O    1 ? 
HETATM 5056 O O    . HOH C 3 .   ? -40.111 15.859  -12.336 1 63.049  ? 529 HOH A O    1 ? 
HETATM 5057 O O    . HOH C 3 .   ? -12.964 -17.018 -10.367 1 64.84   ? 530 HOH A O    1 ? 
HETATM 5058 O O    . HOH C 3 .   ? -44.344 -20.287 0.639   1 59.746  ? 531 HOH A O    1 ? 
HETATM 5059 O O    . HOH C 3 .   ? -24.323 -18.492 -18.306 1 55.215  ? 532 HOH A O    1 ? 
HETATM 5060 O O    . HOH C 3 .   ? -20.466 -24.201 -20.19  1 59.983  ? 533 HOH A O    1 ? 
HETATM 5061 O O    . HOH C 3 .   ? -41.085 -23.771 -20.67  1 56.631  ? 534 HOH A O    1 ? 
HETATM 5062 O O    . HOH C 3 .   ? -47.609 2.167   -22.013 1 54.953  ? 535 HOH A O    1 ? 
HETATM 5063 O O    . HOH C 3 .   ? -20.796 -13.273 -14.005 1 48.257  ? 536 HOH A O    1 ? 
HETATM 5064 O O    . HOH C 3 .   ? -47.925 -3.395  -25.185 1 52.805  ? 537 HOH A O    1 ? 
HETATM 5065 O O    . HOH C 3 .   ? -19.973 -21.078 2.733   1 42.806  ? 538 HOH A O    1 ? 
HETATM 5066 O O    . HOH C 3 .   ? -39.038 13.692  -5.667  1 59.581  ? 539 HOH A O    1 ? 
HETATM 5067 O O    . HOH C 3 .   ? -36.618 -5.736  10.819  1 69.833  ? 540 HOH A O    1 ? 
HETATM 5068 O O    . HOH C 3 .   ? -49.852 -24.113 -20.474 1 63.212  ? 541 HOH A O    1 ? 
HETATM 5069 O O    . HOH C 3 .   ? -47.667 13.889  -7.744  1 76.562  ? 542 HOH A O    1 ? 
HETATM 5070 O O    . HOH C 3 .   ? -18.526 -17.552 -14.686 1 61.434  ? 543 HOH A O    1 ? 
# 
