data_9HNB
# 
_entry.id   9HNB 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9HNB         pdb_00009hnb 10.2210/pdb9hnb/pdb 
WWPDB D_1292143828 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-05-14 ? 
2 'Structure model' 1 1 2025-05-21 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            citation 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume' 
2 2 'Structure model' '_citation.page_first'     
3 2 'Structure model' '_citation.page_last'      
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9HNB 
_pdbx_database_status.recvd_initial_deposition_date   2024-12-10 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 giarita.ferraro@unina.it   Giarita   Ferraro ? 'principal investigator/group leader' 0000-0001-9385-2429 
3 antonello.merlino@unina.it Antonello Merlino ? 'principal investigator/group leader' 0000-0002-1045-7720 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Ferraro, G.' 1 ? 
'Merlino, A.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Inorg.Chem. 
_citation.journal_id_ASTM           INOCAJ 
_citation.journal_id_CSD            0009 
_citation.journal_id_ISSN           0020-1669 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            64 
_citation.language                  ? 
_citation.page_first                8895 
_citation.page_last                 8905 
_citation.title                     
'Cytotoxicity and Binding to DNA, Lysozyme, Ribonuclease A, and Human Serum Albumin of the Diiodido Analog of Picoplatin.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acs.inorgchem.4c05424 
_citation.pdbx_database_id_PubMed   40312957 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Ferraro, G.'    1 ?                   
primary 'Pracharova, J.' 2 0000-0001-7324-8347 
primary 'Gotte, G.'      3 0000-0003-3179-7158 
primary 'Massai, L.'     4 0000-0003-0765-1802 
primary 'Berecka, M.'    5 ?                   
primary 'Starha, P.'     6 0000-0003-0422-045X 
primary 'Messori, L.'    7 0000-0002-9490-8014 
primary 'Merlino, A.'    8 0000-0002-1045-7720 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     nat 'Serum albumin'     66571.219 1 ? ? ? ? 
2 non-polymer syn 'PLATINUM (II) ION' 195.078   3 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;DAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATL
RETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKR
YKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTK
VHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYA
EAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGE
YKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTES
LVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCK
ADDKETCFAEEGKKLVAASQAALGL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;DAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATL
RETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKR
YKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTK
VHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYA
EAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGE
YKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTES
LVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCK
ADDKETCFAEEGKKLVAASQAALGL
;
_entity_poly.pdbx_strand_id                 AAA 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'PLATINUM (II) ION' 
_pdbx_entity_nonpoly.comp_id     PT 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ASP n 
1 2   ALA n 
1 3   HIS n 
1 4   LYS n 
1 5   SER n 
1 6   GLU n 
1 7   VAL n 
1 8   ALA n 
1 9   HIS n 
1 10  ARG n 
1 11  PHE n 
1 12  LYS n 
1 13  ASP n 
1 14  LEU n 
1 15  GLY n 
1 16  GLU n 
1 17  GLU n 
1 18  ASN n 
1 19  PHE n 
1 20  LYS n 
1 21  ALA n 
1 22  LEU n 
1 23  VAL n 
1 24  LEU n 
1 25  ILE n 
1 26  ALA n 
1 27  PHE n 
1 28  ALA n 
1 29  GLN n 
1 30  TYR n 
1 31  LEU n 
1 32  GLN n 
1 33  GLN n 
1 34  CYS n 
1 35  PRO n 
1 36  PHE n 
1 37  GLU n 
1 38  ASP n 
1 39  HIS n 
1 40  VAL n 
1 41  LYS n 
1 42  LEU n 
1 43  VAL n 
1 44  ASN n 
1 45  GLU n 
1 46  VAL n 
1 47  THR n 
1 48  GLU n 
1 49  PHE n 
1 50  ALA n 
1 51  LYS n 
1 52  THR n 
1 53  CYS n 
1 54  VAL n 
1 55  ALA n 
1 56  ASP n 
1 57  GLU n 
1 58  SER n 
1 59  ALA n 
1 60  GLU n 
1 61  ASN n 
1 62  CYS n 
1 63  ASP n 
1 64  LYS n 
1 65  SER n 
1 66  LEU n 
1 67  HIS n 
1 68  THR n 
1 69  LEU n 
1 70  PHE n 
1 71  GLY n 
1 72  ASP n 
1 73  LYS n 
1 74  LEU n 
1 75  CYS n 
1 76  THR n 
1 77  VAL n 
1 78  ALA n 
1 79  THR n 
1 80  LEU n 
1 81  ARG n 
1 82  GLU n 
1 83  THR n 
1 84  TYR n 
1 85  GLY n 
1 86  GLU n 
1 87  MET n 
1 88  ALA n 
1 89  ASP n 
1 90  CYS n 
1 91  CYS n 
1 92  ALA n 
1 93  LYS n 
1 94  GLN n 
1 95  GLU n 
1 96  PRO n 
1 97  GLU n 
1 98  ARG n 
1 99  ASN n 
1 100 GLU n 
1 101 CYS n 
1 102 PHE n 
1 103 LEU n 
1 104 GLN n 
1 105 HIS n 
1 106 LYS n 
1 107 ASP n 
1 108 ASP n 
1 109 ASN n 
1 110 PRO n 
1 111 ASN n 
1 112 LEU n 
1 113 PRO n 
1 114 ARG n 
1 115 LEU n 
1 116 VAL n 
1 117 ARG n 
1 118 PRO n 
1 119 GLU n 
1 120 VAL n 
1 121 ASP n 
1 122 VAL n 
1 123 MET n 
1 124 CYS n 
1 125 THR n 
1 126 ALA n 
1 127 PHE n 
1 128 HIS n 
1 129 ASP n 
1 130 ASN n 
1 131 GLU n 
1 132 GLU n 
1 133 THR n 
1 134 PHE n 
1 135 LEU n 
1 136 LYS n 
1 137 LYS n 
1 138 TYR n 
1 139 LEU n 
1 140 TYR n 
1 141 GLU n 
1 142 ILE n 
1 143 ALA n 
1 144 ARG n 
1 145 ARG n 
1 146 HIS n 
1 147 PRO n 
1 148 TYR n 
1 149 PHE n 
1 150 TYR n 
1 151 ALA n 
1 152 PRO n 
1 153 GLU n 
1 154 LEU n 
1 155 LEU n 
1 156 PHE n 
1 157 PHE n 
1 158 ALA n 
1 159 LYS n 
1 160 ARG n 
1 161 TYR n 
1 162 LYS n 
1 163 ALA n 
1 164 ALA n 
1 165 PHE n 
1 166 THR n 
1 167 GLU n 
1 168 CYS n 
1 169 CYS n 
1 170 GLN n 
1 171 ALA n 
1 172 ALA n 
1 173 ASP n 
1 174 LYS n 
1 175 ALA n 
1 176 ALA n 
1 177 CYS n 
1 178 LEU n 
1 179 LEU n 
1 180 PRO n 
1 181 LYS n 
1 182 LEU n 
1 183 ASP n 
1 184 GLU n 
1 185 LEU n 
1 186 ARG n 
1 187 ASP n 
1 188 GLU n 
1 189 GLY n 
1 190 LYS n 
1 191 ALA n 
1 192 SER n 
1 193 SER n 
1 194 ALA n 
1 195 LYS n 
1 196 GLN n 
1 197 ARG n 
1 198 LEU n 
1 199 LYS n 
1 200 CYS n 
1 201 ALA n 
1 202 SER n 
1 203 LEU n 
1 204 GLN n 
1 205 LYS n 
1 206 PHE n 
1 207 GLY n 
1 208 GLU n 
1 209 ARG n 
1 210 ALA n 
1 211 PHE n 
1 212 LYS n 
1 213 ALA n 
1 214 TRP n 
1 215 ALA n 
1 216 VAL n 
1 217 ALA n 
1 218 ARG n 
1 219 LEU n 
1 220 SER n 
1 221 GLN n 
1 222 ARG n 
1 223 PHE n 
1 224 PRO n 
1 225 LYS n 
1 226 ALA n 
1 227 GLU n 
1 228 PHE n 
1 229 ALA n 
1 230 GLU n 
1 231 VAL n 
1 232 SER n 
1 233 LYS n 
1 234 LEU n 
1 235 VAL n 
1 236 THR n 
1 237 ASP n 
1 238 LEU n 
1 239 THR n 
1 240 LYS n 
1 241 VAL n 
1 242 HIS n 
1 243 THR n 
1 244 GLU n 
1 245 CYS n 
1 246 CYS n 
1 247 HIS n 
1 248 GLY n 
1 249 ASP n 
1 250 LEU n 
1 251 LEU n 
1 252 GLU n 
1 253 CYS n 
1 254 ALA n 
1 255 ASP n 
1 256 ASP n 
1 257 ARG n 
1 258 ALA n 
1 259 ASP n 
1 260 LEU n 
1 261 ALA n 
1 262 LYS n 
1 263 TYR n 
1 264 ILE n 
1 265 CYS n 
1 266 GLU n 
1 267 ASN n 
1 268 GLN n 
1 269 ASP n 
1 270 SER n 
1 271 ILE n 
1 272 SER n 
1 273 SER n 
1 274 LYS n 
1 275 LEU n 
1 276 LYS n 
1 277 GLU n 
1 278 CYS n 
1 279 CYS n 
1 280 GLU n 
1 281 LYS n 
1 282 PRO n 
1 283 LEU n 
1 284 LEU n 
1 285 GLU n 
1 286 LYS n 
1 287 SER n 
1 288 HIS n 
1 289 CYS n 
1 290 ILE n 
1 291 ALA n 
1 292 GLU n 
1 293 VAL n 
1 294 GLU n 
1 295 ASN n 
1 296 ASP n 
1 297 GLU n 
1 298 MET n 
1 299 PRO n 
1 300 ALA n 
1 301 ASP n 
1 302 LEU n 
1 303 PRO n 
1 304 SER n 
1 305 LEU n 
1 306 ALA n 
1 307 ALA n 
1 308 ASP n 
1 309 PHE n 
1 310 VAL n 
1 311 GLU n 
1 312 SER n 
1 313 LYS n 
1 314 ASP n 
1 315 VAL n 
1 316 CYS n 
1 317 LYS n 
1 318 ASN n 
1 319 TYR n 
1 320 ALA n 
1 321 GLU n 
1 322 ALA n 
1 323 LYS n 
1 324 ASP n 
1 325 VAL n 
1 326 PHE n 
1 327 LEU n 
1 328 GLY n 
1 329 MET n 
1 330 PHE n 
1 331 LEU n 
1 332 TYR n 
1 333 GLU n 
1 334 TYR n 
1 335 ALA n 
1 336 ARG n 
1 337 ARG n 
1 338 HIS n 
1 339 PRO n 
1 340 ASP n 
1 341 TYR n 
1 342 SER n 
1 343 VAL n 
1 344 VAL n 
1 345 LEU n 
1 346 LEU n 
1 347 LEU n 
1 348 ARG n 
1 349 LEU n 
1 350 ALA n 
1 351 LYS n 
1 352 THR n 
1 353 TYR n 
1 354 GLU n 
1 355 THR n 
1 356 THR n 
1 357 LEU n 
1 358 GLU n 
1 359 LYS n 
1 360 CYS n 
1 361 CYS n 
1 362 ALA n 
1 363 ALA n 
1 364 ALA n 
1 365 ASP n 
1 366 PRO n 
1 367 HIS n 
1 368 GLU n 
1 369 CYS n 
1 370 TYR n 
1 371 ALA n 
1 372 LYS n 
1 373 VAL n 
1 374 PHE n 
1 375 ASP n 
1 376 GLU n 
1 377 PHE n 
1 378 LYS n 
1 379 PRO n 
1 380 LEU n 
1 381 VAL n 
1 382 GLU n 
1 383 GLU n 
1 384 PRO n 
1 385 GLN n 
1 386 ASN n 
1 387 LEU n 
1 388 ILE n 
1 389 LYS n 
1 390 GLN n 
1 391 ASN n 
1 392 CYS n 
1 393 GLU n 
1 394 LEU n 
1 395 PHE n 
1 396 GLU n 
1 397 GLN n 
1 398 LEU n 
1 399 GLY n 
1 400 GLU n 
1 401 TYR n 
1 402 LYS n 
1 403 PHE n 
1 404 GLN n 
1 405 ASN n 
1 406 ALA n 
1 407 LEU n 
1 408 LEU n 
1 409 VAL n 
1 410 ARG n 
1 411 TYR n 
1 412 THR n 
1 413 LYS n 
1 414 LYS n 
1 415 VAL n 
1 416 PRO n 
1 417 GLN n 
1 418 VAL n 
1 419 SER n 
1 420 THR n 
1 421 PRO n 
1 422 THR n 
1 423 LEU n 
1 424 VAL n 
1 425 GLU n 
1 426 VAL n 
1 427 SER n 
1 428 ARG n 
1 429 ASN n 
1 430 LEU n 
1 431 GLY n 
1 432 LYS n 
1 433 VAL n 
1 434 GLY n 
1 435 SER n 
1 436 LYS n 
1 437 CYS n 
1 438 CYS n 
1 439 LYS n 
1 440 HIS n 
1 441 PRO n 
1 442 GLU n 
1 443 ALA n 
1 444 LYS n 
1 445 ARG n 
1 446 MET n 
1 447 PRO n 
1 448 CYS n 
1 449 ALA n 
1 450 GLU n 
1 451 ASP n 
1 452 TYR n 
1 453 LEU n 
1 454 SER n 
1 455 VAL n 
1 456 VAL n 
1 457 LEU n 
1 458 ASN n 
1 459 GLN n 
1 460 LEU n 
1 461 CYS n 
1 462 VAL n 
1 463 LEU n 
1 464 HIS n 
1 465 GLU n 
1 466 LYS n 
1 467 THR n 
1 468 PRO n 
1 469 VAL n 
1 470 SER n 
1 471 ASP n 
1 472 ARG n 
1 473 VAL n 
1 474 THR n 
1 475 LYS n 
1 476 CYS n 
1 477 CYS n 
1 478 THR n 
1 479 GLU n 
1 480 SER n 
1 481 LEU n 
1 482 VAL n 
1 483 ASN n 
1 484 ARG n 
1 485 ARG n 
1 486 PRO n 
1 487 CYS n 
1 488 PHE n 
1 489 SER n 
1 490 ALA n 
1 491 LEU n 
1 492 GLU n 
1 493 VAL n 
1 494 ASP n 
1 495 GLU n 
1 496 THR n 
1 497 TYR n 
1 498 VAL n 
1 499 PRO n 
1 500 LYS n 
1 501 GLU n 
1 502 PHE n 
1 503 ASN n 
1 504 ALA n 
1 505 GLU n 
1 506 THR n 
1 507 PHE n 
1 508 THR n 
1 509 PHE n 
1 510 HIS n 
1 511 ALA n 
1 512 ASP n 
1 513 ILE n 
1 514 CYS n 
1 515 THR n 
1 516 LEU n 
1 517 SER n 
1 518 GLU n 
1 519 LYS n 
1 520 GLU n 
1 521 ARG n 
1 522 GLN n 
1 523 ILE n 
1 524 LYS n 
1 525 LYS n 
1 526 GLN n 
1 527 THR n 
1 528 ALA n 
1 529 LEU n 
1 530 VAL n 
1 531 GLU n 
1 532 LEU n 
1 533 VAL n 
1 534 LYS n 
1 535 HIS n 
1 536 LYS n 
1 537 PRO n 
1 538 LYS n 
1 539 ALA n 
1 540 THR n 
1 541 LYS n 
1 542 GLU n 
1 543 GLN n 
1 544 LEU n 
1 545 LYS n 
1 546 ALA n 
1 547 VAL n 
1 548 MET n 
1 549 ASP n 
1 550 ASP n 
1 551 PHE n 
1 552 ALA n 
1 553 ALA n 
1 554 PHE n 
1 555 VAL n 
1 556 GLU n 
1 557 LYS n 
1 558 CYS n 
1 559 CYS n 
1 560 LYS n 
1 561 ALA n 
1 562 ASP n 
1 563 ASP n 
1 564 LYS n 
1 565 GLU n 
1 566 THR n 
1 567 CYS n 
1 568 PHE n 
1 569 ALA n 
1 570 GLU n 
1 571 GLU n 
1 572 GLY n 
1 573 LYS n 
1 574 LYS n 
1 575 LEU n 
1 576 VAL n 
1 577 ALA n 
1 578 ALA n 
1 579 SER n 
1 580 GLN n 
1 581 ALA n 
1 582 ALA n 
1 583 LEU n 
1 584 GLY n 
1 585 LEU n 
# 
_entity_src_nat.entity_id                  1 
_entity_src_nat.pdbx_src_id                1 
_entity_src_nat.pdbx_alt_source_flag       sample 
_entity_src_nat.pdbx_beg_seq_num           1 
_entity_src_nat.pdbx_end_seq_num           585 
_entity_src_nat.common_name                human 
_entity_src_nat.pdbx_organism_scientific   'Homo sapiens' 
_entity_src_nat.pdbx_ncbi_taxonomy_id      9606 
_entity_src_nat.genus                      ? 
_entity_src_nat.species                    ? 
_entity_src_nat.strain                     ? 
_entity_src_nat.tissue                     ? 
_entity_src_nat.tissue_fraction            ? 
_entity_src_nat.pdbx_secretion             ? 
_entity_src_nat.pdbx_fragment              ? 
_entity_src_nat.pdbx_variant               ? 
_entity_src_nat.pdbx_cell_line             ? 
_entity_src_nat.pdbx_atcc                  ? 
_entity_src_nat.pdbx_cellular_location     ? 
_entity_src_nat.pdbx_organ                 ? 
_entity_src_nat.pdbx_organelle             ? 
_entity_src_nat.pdbx_cell                  ? 
_entity_src_nat.pdbx_plasmid_name          ? 
_entity_src_nat.pdbx_plasmid_details       ? 
_entity_src_nat.details                    ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE             ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE            ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE          ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'     ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE            ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE           ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'     ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE             ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE           ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE          ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE             ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE              ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE          ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE       ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE             ? 'C5 H9 N O2'     115.130 
PT  non-polymer         . 'PLATINUM (II) ION' ? 'Pt 2'           195.078 
SER 'L-peptide linking' y SERINE              ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE           ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN          ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE            ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE              ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ASP 1   1   ?   ?   ?   AAA . n 
A 1 2   ALA 2   2   ?   ?   ?   AAA . n 
A 1 3   HIS 3   3   ?   ?   ?   AAA . n 
A 1 4   LYS 4   4   ?   ?   ?   AAA . n 
A 1 5   SER 5   5   5   SER SER AAA . n 
A 1 6   GLU 6   6   6   GLU GLU AAA . n 
A 1 7   VAL 7   7   7   VAL VAL AAA . n 
A 1 8   ALA 8   8   8   ALA ALA AAA . n 
A 1 9   HIS 9   9   9   HIS HIS AAA . n 
A 1 10  ARG 10  10  10  ARG ARG AAA . n 
A 1 11  PHE 11  11  11  PHE PHE AAA . n 
A 1 12  LYS 12  12  12  LYS LYS AAA . n 
A 1 13  ASP 13  13  13  ASP ASP AAA . n 
A 1 14  LEU 14  14  14  LEU LEU AAA . n 
A 1 15  GLY 15  15  15  GLY GLY AAA . n 
A 1 16  GLU 16  16  16  GLU GLU AAA . n 
A 1 17  GLU 17  17  17  GLU GLU AAA . n 
A 1 18  ASN 18  18  18  ASN ASN AAA . n 
A 1 19  PHE 19  19  19  PHE PHE AAA . n 
A 1 20  LYS 20  20  20  LYS LYS AAA . n 
A 1 21  ALA 21  21  21  ALA ALA AAA . n 
A 1 22  LEU 22  22  22  LEU LEU AAA . n 
A 1 23  VAL 23  23  23  VAL VAL AAA . n 
A 1 24  LEU 24  24  24  LEU LEU AAA . n 
A 1 25  ILE 25  25  25  ILE ILE AAA . n 
A 1 26  ALA 26  26  26  ALA ALA AAA . n 
A 1 27  PHE 27  27  27  PHE PHE AAA . n 
A 1 28  ALA 28  28  28  ALA ALA AAA . n 
A 1 29  GLN 29  29  29  GLN GLN AAA . n 
A 1 30  TYR 30  30  30  TYR TYR AAA . n 
A 1 31  LEU 31  31  31  LEU LEU AAA . n 
A 1 32  GLN 32  32  32  GLN GLN AAA . n 
A 1 33  GLN 33  33  33  GLN GLN AAA . n 
A 1 34  CYS 34  34  34  CYS CYS AAA . n 
A 1 35  PRO 35  35  35  PRO PRO AAA . n 
A 1 36  PHE 36  36  36  PHE PHE AAA . n 
A 1 37  GLU 37  37  37  GLU GLU AAA . n 
A 1 38  ASP 38  38  38  ASP ASP AAA . n 
A 1 39  HIS 39  39  39  HIS HIS AAA . n 
A 1 40  VAL 40  40  40  VAL VAL AAA . n 
A 1 41  LYS 41  41  41  LYS LYS AAA . n 
A 1 42  LEU 42  42  42  LEU LEU AAA . n 
A 1 43  VAL 43  43  43  VAL VAL AAA . n 
A 1 44  ASN 44  44  44  ASN ASN AAA . n 
A 1 45  GLU 45  45  45  GLU GLU AAA . n 
A 1 46  VAL 46  46  46  VAL VAL AAA . n 
A 1 47  THR 47  47  47  THR THR AAA . n 
A 1 48  GLU 48  48  48  GLU GLU AAA . n 
A 1 49  PHE 49  49  49  PHE PHE AAA . n 
A 1 50  ALA 50  50  50  ALA ALA AAA . n 
A 1 51  LYS 51  51  51  LYS LYS AAA . n 
A 1 52  THR 52  52  52  THR THR AAA . n 
A 1 53  CYS 53  53  53  CYS CYS AAA . n 
A 1 54  VAL 54  54  54  VAL VAL AAA . n 
A 1 55  ALA 55  55  55  ALA ALA AAA . n 
A 1 56  ASP 56  56  56  ASP ASP AAA . n 
A 1 57  GLU 57  57  57  GLU GLU AAA . n 
A 1 58  SER 58  58  58  SER SER AAA . n 
A 1 59  ALA 59  59  59  ALA ALA AAA . n 
A 1 60  GLU 60  60  60  GLU GLU AAA . n 
A 1 61  ASN 61  61  61  ASN ASN AAA . n 
A 1 62  CYS 62  62  62  CYS CYS AAA . n 
A 1 63  ASP 63  63  63  ASP ASP AAA . n 
A 1 64  LYS 64  64  64  LYS LYS AAA . n 
A 1 65  SER 65  65  65  SER SER AAA . n 
A 1 66  LEU 66  66  66  LEU LEU AAA . n 
A 1 67  HIS 67  67  67  HIS HIS AAA . n 
A 1 68  THR 68  68  68  THR THR AAA . n 
A 1 69  LEU 69  69  69  LEU LEU AAA . n 
A 1 70  PHE 70  70  70  PHE PHE AAA . n 
A 1 71  GLY 71  71  71  GLY GLY AAA . n 
A 1 72  ASP 72  72  72  ASP ASP AAA . n 
A 1 73  LYS 73  73  73  LYS LYS AAA . n 
A 1 74  LEU 74  74  74  LEU LEU AAA . n 
A 1 75  CYS 75  75  75  CYS CYS AAA . n 
A 1 76  THR 76  76  76  THR THR AAA . n 
A 1 77  VAL 77  77  ?   ?   ?   AAA . n 
A 1 78  ALA 78  78  ?   ?   ?   AAA . n 
A 1 79  THR 79  79  ?   ?   ?   AAA . n 
A 1 80  LEU 80  80  ?   ?   ?   AAA . n 
A 1 81  ARG 81  81  ?   ?   ?   AAA . n 
A 1 82  GLU 82  82  ?   ?   ?   AAA . n 
A 1 83  THR 83  83  ?   ?   ?   AAA . n 
A 1 84  TYR 84  84  ?   ?   ?   AAA . n 
A 1 85  GLY 85  85  ?   ?   ?   AAA . n 
A 1 86  GLU 86  86  ?   ?   ?   AAA . n 
A 1 87  MET 87  87  ?   ?   ?   AAA . n 
A 1 88  ALA 88  88  ?   ?   ?   AAA . n 
A 1 89  ASP 89  89  89  ASP ASP AAA . n 
A 1 90  CYS 90  90  90  CYS CYS AAA . n 
A 1 91  CYS 91  91  91  CYS CYS AAA . n 
A 1 92  ALA 92  92  92  ALA ALA AAA . n 
A 1 93  LYS 93  93  93  LYS LYS AAA . n 
A 1 94  GLN 94  94  94  GLN GLN AAA . n 
A 1 95  GLU 95  95  95  GLU GLU AAA . n 
A 1 96  PRO 96  96  96  PRO PRO AAA . n 
A 1 97  GLU 97  97  97  GLU GLU AAA . n 
A 1 98  ARG 98  98  98  ARG ARG AAA . n 
A 1 99  ASN 99  99  99  ASN ASN AAA . n 
A 1 100 GLU 100 100 100 GLU GLU AAA . n 
A 1 101 CYS 101 101 101 CYS CYS AAA . n 
A 1 102 PHE 102 102 102 PHE PHE AAA . n 
A 1 103 LEU 103 103 103 LEU LEU AAA . n 
A 1 104 GLN 104 104 104 GLN GLN AAA . n 
A 1 105 HIS 105 105 105 HIS HIS AAA . n 
A 1 106 LYS 106 106 106 LYS LYS AAA . n 
A 1 107 ASP 107 107 107 ASP ASP AAA . n 
A 1 108 ASP 108 108 108 ASP ASP AAA . n 
A 1 109 ASN 109 109 109 ASN ASN AAA . n 
A 1 110 PRO 110 110 110 PRO PRO AAA . n 
A 1 111 ASN 111 111 111 ASN ASN AAA . n 
A 1 112 LEU 112 112 112 LEU LEU AAA . n 
A 1 113 PRO 113 113 113 PRO PRO AAA . n 
A 1 114 ARG 114 114 114 ARG ARG AAA . n 
A 1 115 LEU 115 115 115 LEU LEU AAA . n 
A 1 116 VAL 116 116 116 VAL VAL AAA . n 
A 1 117 ARG 117 117 117 ARG ARG AAA . n 
A 1 118 PRO 118 118 118 PRO PRO AAA . n 
A 1 119 GLU 119 119 119 GLU GLU AAA . n 
A 1 120 VAL 120 120 120 VAL VAL AAA . n 
A 1 121 ASP 121 121 121 ASP ASP AAA . n 
A 1 122 VAL 122 122 122 VAL VAL AAA . n 
A 1 123 MET 123 123 123 MET MET AAA . n 
A 1 124 CYS 124 124 124 CYS CYS AAA . n 
A 1 125 THR 125 125 125 THR THR AAA . n 
A 1 126 ALA 126 126 126 ALA ALA AAA . n 
A 1 127 PHE 127 127 127 PHE PHE AAA . n 
A 1 128 HIS 128 128 128 HIS HIS AAA . n 
A 1 129 ASP 129 129 129 ASP ASP AAA . n 
A 1 130 ASN 130 130 130 ASN ASN AAA . n 
A 1 131 GLU 131 131 131 GLU GLU AAA . n 
A 1 132 GLU 132 132 132 GLU GLU AAA . n 
A 1 133 THR 133 133 133 THR THR AAA . n 
A 1 134 PHE 134 134 134 PHE PHE AAA . n 
A 1 135 LEU 135 135 135 LEU LEU AAA . n 
A 1 136 LYS 136 136 136 LYS LYS AAA . n 
A 1 137 LYS 137 137 137 LYS LYS AAA . n 
A 1 138 TYR 138 138 138 TYR TYR AAA . n 
A 1 139 LEU 139 139 139 LEU LEU AAA . n 
A 1 140 TYR 140 140 140 TYR TYR AAA . n 
A 1 141 GLU 141 141 141 GLU GLU AAA . n 
A 1 142 ILE 142 142 142 ILE ILE AAA . n 
A 1 143 ALA 143 143 143 ALA ALA AAA . n 
A 1 144 ARG 144 144 144 ARG ARG AAA . n 
A 1 145 ARG 145 145 145 ARG ARG AAA . n 
A 1 146 HIS 146 146 146 HIS HIS AAA . n 
A 1 147 PRO 147 147 147 PRO PRO AAA . n 
A 1 148 TYR 148 148 148 TYR TYR AAA . n 
A 1 149 PHE 149 149 149 PHE PHE AAA . n 
A 1 150 TYR 150 150 150 TYR TYR AAA . n 
A 1 151 ALA 151 151 151 ALA ALA AAA . n 
A 1 152 PRO 152 152 152 PRO PRO AAA . n 
A 1 153 GLU 153 153 153 GLU GLU AAA . n 
A 1 154 LEU 154 154 154 LEU LEU AAA . n 
A 1 155 LEU 155 155 155 LEU LEU AAA . n 
A 1 156 PHE 156 156 156 PHE PHE AAA . n 
A 1 157 PHE 157 157 157 PHE PHE AAA . n 
A 1 158 ALA 158 158 158 ALA ALA AAA . n 
A 1 159 LYS 159 159 159 LYS LYS AAA . n 
A 1 160 ARG 160 160 160 ARG ARG AAA . n 
A 1 161 TYR 161 161 161 TYR TYR AAA . n 
A 1 162 LYS 162 162 162 LYS LYS AAA . n 
A 1 163 ALA 163 163 163 ALA ALA AAA . n 
A 1 164 ALA 164 164 164 ALA ALA AAA . n 
A 1 165 PHE 165 165 165 PHE PHE AAA . n 
A 1 166 THR 166 166 166 THR THR AAA . n 
A 1 167 GLU 167 167 167 GLU GLU AAA . n 
A 1 168 CYS 168 168 168 CYS CYS AAA . n 
A 1 169 CYS 169 169 169 CYS CYS AAA . n 
A 1 170 GLN 170 170 170 GLN GLN AAA . n 
A 1 171 ALA 171 171 171 ALA ALA AAA . n 
A 1 172 ALA 172 172 172 ALA ALA AAA . n 
A 1 173 ASP 173 173 173 ASP ASP AAA . n 
A 1 174 LYS 174 174 174 LYS LYS AAA . n 
A 1 175 ALA 175 175 175 ALA ALA AAA . n 
A 1 176 ALA 176 176 176 ALA ALA AAA . n 
A 1 177 CYS 177 177 177 CYS CYS AAA . n 
A 1 178 LEU 178 178 178 LEU LEU AAA . n 
A 1 179 LEU 179 179 179 LEU LEU AAA . n 
A 1 180 PRO 180 180 180 PRO PRO AAA . n 
A 1 181 LYS 181 181 181 LYS LYS AAA . n 
A 1 182 LEU 182 182 182 LEU LEU AAA . n 
A 1 183 ASP 183 183 183 ASP ASP AAA . n 
A 1 184 GLU 184 184 184 GLU GLU AAA . n 
A 1 185 LEU 185 185 185 LEU LEU AAA . n 
A 1 186 ARG 186 186 186 ARG ARG AAA . n 
A 1 187 ASP 187 187 187 ASP ASP AAA . n 
A 1 188 GLU 188 188 188 GLU GLU AAA . n 
A 1 189 GLY 189 189 189 GLY GLY AAA . n 
A 1 190 LYS 190 190 190 LYS LYS AAA . n 
A 1 191 ALA 191 191 191 ALA ALA AAA . n 
A 1 192 SER 192 192 192 SER SER AAA . n 
A 1 193 SER 193 193 193 SER SER AAA . n 
A 1 194 ALA 194 194 194 ALA ALA AAA . n 
A 1 195 LYS 195 195 195 LYS LYS AAA . n 
A 1 196 GLN 196 196 196 GLN GLN AAA . n 
A 1 197 ARG 197 197 197 ARG ARG AAA . n 
A 1 198 LEU 198 198 198 LEU LEU AAA . n 
A 1 199 LYS 199 199 199 LYS LYS AAA . n 
A 1 200 CYS 200 200 200 CYS CYS AAA . n 
A 1 201 ALA 201 201 201 ALA ALA AAA . n 
A 1 202 SER 202 202 202 SER SER AAA . n 
A 1 203 LEU 203 203 203 LEU LEU AAA . n 
A 1 204 GLN 204 204 204 GLN GLN AAA . n 
A 1 205 LYS 205 205 205 LYS LYS AAA . n 
A 1 206 PHE 206 206 206 PHE PHE AAA . n 
A 1 207 GLY 207 207 207 GLY GLY AAA . n 
A 1 208 GLU 208 208 208 GLU GLU AAA . n 
A 1 209 ARG 209 209 209 ARG ARG AAA . n 
A 1 210 ALA 210 210 210 ALA ALA AAA . n 
A 1 211 PHE 211 211 211 PHE PHE AAA . n 
A 1 212 LYS 212 212 212 LYS LYS AAA . n 
A 1 213 ALA 213 213 213 ALA ALA AAA . n 
A 1 214 TRP 214 214 214 TRP TRP AAA . n 
A 1 215 ALA 215 215 215 ALA ALA AAA . n 
A 1 216 VAL 216 216 216 VAL VAL AAA . n 
A 1 217 ALA 217 217 217 ALA ALA AAA . n 
A 1 218 ARG 218 218 218 ARG ARG AAA . n 
A 1 219 LEU 219 219 219 LEU LEU AAA . n 
A 1 220 SER 220 220 220 SER SER AAA . n 
A 1 221 GLN 221 221 221 GLN GLN AAA . n 
A 1 222 ARG 222 222 222 ARG ARG AAA . n 
A 1 223 PHE 223 223 223 PHE PHE AAA . n 
A 1 224 PRO 224 224 224 PRO PRO AAA . n 
A 1 225 LYS 225 225 225 LYS LYS AAA . n 
A 1 226 ALA 226 226 226 ALA ALA AAA . n 
A 1 227 GLU 227 227 227 GLU GLU AAA . n 
A 1 228 PHE 228 228 228 PHE PHE AAA . n 
A 1 229 ALA 229 229 229 ALA ALA AAA . n 
A 1 230 GLU 230 230 230 GLU GLU AAA . n 
A 1 231 VAL 231 231 231 VAL VAL AAA . n 
A 1 232 SER 232 232 232 SER SER AAA . n 
A 1 233 LYS 233 233 233 LYS LYS AAA . n 
A 1 234 LEU 234 234 234 LEU LEU AAA . n 
A 1 235 VAL 235 235 235 VAL VAL AAA . n 
A 1 236 THR 236 236 236 THR THR AAA . n 
A 1 237 ASP 237 237 237 ASP ASP AAA . n 
A 1 238 LEU 238 238 238 LEU LEU AAA . n 
A 1 239 THR 239 239 239 THR THR AAA . n 
A 1 240 LYS 240 240 240 LYS LYS AAA . n 
A 1 241 VAL 241 241 241 VAL VAL AAA . n 
A 1 242 HIS 242 242 242 HIS HIS AAA . n 
A 1 243 THR 243 243 243 THR THR AAA . n 
A 1 244 GLU 244 244 244 GLU GLU AAA . n 
A 1 245 CYS 245 245 245 CYS CYS AAA . n 
A 1 246 CYS 246 246 246 CYS CYS AAA . n 
A 1 247 HIS 247 247 247 HIS HIS AAA . n 
A 1 248 GLY 248 248 248 GLY GLY AAA . n 
A 1 249 ASP 249 249 249 ASP ASP AAA . n 
A 1 250 LEU 250 250 250 LEU LEU AAA . n 
A 1 251 LEU 251 251 251 LEU LEU AAA . n 
A 1 252 GLU 252 252 252 GLU GLU AAA . n 
A 1 253 CYS 253 253 253 CYS CYS AAA . n 
A 1 254 ALA 254 254 254 ALA ALA AAA . n 
A 1 255 ASP 255 255 255 ASP ASP AAA . n 
A 1 256 ASP 256 256 256 ASP ASP AAA . n 
A 1 257 ARG 257 257 257 ARG ARG AAA . n 
A 1 258 ALA 258 258 258 ALA ALA AAA . n 
A 1 259 ASP 259 259 259 ASP ASP AAA . n 
A 1 260 LEU 260 260 260 LEU LEU AAA . n 
A 1 261 ALA 261 261 261 ALA ALA AAA . n 
A 1 262 LYS 262 262 262 LYS LYS AAA . n 
A 1 263 TYR 263 263 263 TYR TYR AAA . n 
A 1 264 ILE 264 264 264 ILE ILE AAA . n 
A 1 265 CYS 265 265 265 CYS CYS AAA . n 
A 1 266 GLU 266 266 266 GLU GLU AAA . n 
A 1 267 ASN 267 267 267 ASN ASN AAA . n 
A 1 268 GLN 268 268 268 GLN GLN AAA . n 
A 1 269 ASP 269 269 269 ASP ASP AAA . n 
A 1 270 SER 270 270 270 SER SER AAA . n 
A 1 271 ILE 271 271 271 ILE ILE AAA . n 
A 1 272 SER 272 272 272 SER SER AAA . n 
A 1 273 SER 273 273 273 SER SER AAA . n 
A 1 274 LYS 274 274 274 LYS LYS AAA . n 
A 1 275 LEU 275 275 275 LEU LEU AAA . n 
A 1 276 LYS 276 276 276 LYS LYS AAA . n 
A 1 277 GLU 277 277 277 GLU GLU AAA . n 
A 1 278 CYS 278 278 278 CYS CYS AAA . n 
A 1 279 CYS 279 279 279 CYS CYS AAA . n 
A 1 280 GLU 280 280 280 GLU GLU AAA . n 
A 1 281 LYS 281 281 281 LYS LYS AAA . n 
A 1 282 PRO 282 282 282 PRO PRO AAA . n 
A 1 283 LEU 283 283 283 LEU LEU AAA . n 
A 1 284 LEU 284 284 284 LEU LEU AAA . n 
A 1 285 GLU 285 285 285 GLU GLU AAA . n 
A 1 286 LYS 286 286 286 LYS LYS AAA . n 
A 1 287 SER 287 287 287 SER SER AAA . n 
A 1 288 HIS 288 288 288 HIS HIS AAA . n 
A 1 289 CYS 289 289 289 CYS CYS AAA . n 
A 1 290 ILE 290 290 290 ILE ILE AAA . n 
A 1 291 ALA 291 291 291 ALA ALA AAA . n 
A 1 292 GLU 292 292 292 GLU GLU AAA . n 
A 1 293 VAL 293 293 293 VAL VAL AAA . n 
A 1 294 GLU 294 294 294 GLU GLU AAA . n 
A 1 295 ASN 295 295 295 ASN ASN AAA . n 
A 1 296 ASP 296 296 296 ASP ASP AAA . n 
A 1 297 GLU 297 297 297 GLU GLU AAA . n 
A 1 298 MET 298 298 298 MET MET AAA . n 
A 1 299 PRO 299 299 299 PRO PRO AAA . n 
A 1 300 ALA 300 300 300 ALA ALA AAA . n 
A 1 301 ASP 301 301 301 ASP ASP AAA . n 
A 1 302 LEU 302 302 302 LEU LEU AAA . n 
A 1 303 PRO 303 303 303 PRO PRO AAA . n 
A 1 304 SER 304 304 304 SER SER AAA . n 
A 1 305 LEU 305 305 305 LEU LEU AAA . n 
A 1 306 ALA 306 306 306 ALA ALA AAA . n 
A 1 307 ALA 307 307 307 ALA ALA AAA . n 
A 1 308 ASP 308 308 308 ASP ASP AAA . n 
A 1 309 PHE 309 309 309 PHE PHE AAA . n 
A 1 310 VAL 310 310 310 VAL VAL AAA . n 
A 1 311 GLU 311 311 311 GLU GLU AAA . n 
A 1 312 SER 312 312 312 SER SER AAA . n 
A 1 313 LYS 313 313 313 LYS LYS AAA . n 
A 1 314 ASP 314 314 314 ASP ASP AAA . n 
A 1 315 VAL 315 315 315 VAL VAL AAA . n 
A 1 316 CYS 316 316 316 CYS CYS AAA . n 
A 1 317 LYS 317 317 317 LYS LYS AAA . n 
A 1 318 ASN 318 318 318 ASN ASN AAA . n 
A 1 319 TYR 319 319 319 TYR TYR AAA . n 
A 1 320 ALA 320 320 320 ALA ALA AAA . n 
A 1 321 GLU 321 321 321 GLU GLU AAA . n 
A 1 322 ALA 322 322 322 ALA ALA AAA . n 
A 1 323 LYS 323 323 323 LYS LYS AAA . n 
A 1 324 ASP 324 324 324 ASP ASP AAA . n 
A 1 325 VAL 325 325 325 VAL VAL AAA . n 
A 1 326 PHE 326 326 326 PHE PHE AAA . n 
A 1 327 LEU 327 327 327 LEU LEU AAA . n 
A 1 328 GLY 328 328 328 GLY GLY AAA . n 
A 1 329 MET 329 329 329 MET MET AAA . n 
A 1 330 PHE 330 330 330 PHE PHE AAA . n 
A 1 331 LEU 331 331 331 LEU LEU AAA . n 
A 1 332 TYR 332 332 332 TYR TYR AAA . n 
A 1 333 GLU 333 333 333 GLU GLU AAA . n 
A 1 334 TYR 334 334 334 TYR TYR AAA . n 
A 1 335 ALA 335 335 335 ALA ALA AAA . n 
A 1 336 ARG 336 336 336 ARG ARG AAA . n 
A 1 337 ARG 337 337 337 ARG ARG AAA . n 
A 1 338 HIS 338 338 338 HIS HIS AAA . n 
A 1 339 PRO 339 339 339 PRO PRO AAA . n 
A 1 340 ASP 340 340 340 ASP ASP AAA . n 
A 1 341 TYR 341 341 341 TYR TYR AAA . n 
A 1 342 SER 342 342 342 SER SER AAA . n 
A 1 343 VAL 343 343 343 VAL VAL AAA . n 
A 1 344 VAL 344 344 344 VAL VAL AAA . n 
A 1 345 LEU 345 345 345 LEU LEU AAA . n 
A 1 346 LEU 346 346 346 LEU LEU AAA . n 
A 1 347 LEU 347 347 347 LEU LEU AAA . n 
A 1 348 ARG 348 348 348 ARG ARG AAA . n 
A 1 349 LEU 349 349 349 LEU LEU AAA . n 
A 1 350 ALA 350 350 350 ALA ALA AAA . n 
A 1 351 LYS 351 351 351 LYS LYS AAA . n 
A 1 352 THR 352 352 352 THR THR AAA . n 
A 1 353 TYR 353 353 353 TYR TYR AAA . n 
A 1 354 GLU 354 354 354 GLU GLU AAA . n 
A 1 355 THR 355 355 355 THR THR AAA . n 
A 1 356 THR 356 356 356 THR THR AAA . n 
A 1 357 LEU 357 357 357 LEU LEU AAA . n 
A 1 358 GLU 358 358 358 GLU GLU AAA . n 
A 1 359 LYS 359 359 359 LYS LYS AAA . n 
A 1 360 CYS 360 360 360 CYS CYS AAA . n 
A 1 361 CYS 361 361 361 CYS CYS AAA . n 
A 1 362 ALA 362 362 362 ALA ALA AAA . n 
A 1 363 ALA 363 363 363 ALA ALA AAA . n 
A 1 364 ALA 364 364 364 ALA ALA AAA . n 
A 1 365 ASP 365 365 365 ASP ASP AAA . n 
A 1 366 PRO 366 366 366 PRO PRO AAA . n 
A 1 367 HIS 367 367 367 HIS HIS AAA . n 
A 1 368 GLU 368 368 368 GLU GLU AAA . n 
A 1 369 CYS 369 369 369 CYS CYS AAA . n 
A 1 370 TYR 370 370 370 TYR TYR AAA . n 
A 1 371 ALA 371 371 371 ALA ALA AAA . n 
A 1 372 LYS 372 372 372 LYS LYS AAA . n 
A 1 373 VAL 373 373 373 VAL VAL AAA . n 
A 1 374 PHE 374 374 374 PHE PHE AAA . n 
A 1 375 ASP 375 375 375 ASP ASP AAA . n 
A 1 376 GLU 376 376 376 GLU GLU AAA . n 
A 1 377 PHE 377 377 377 PHE PHE AAA . n 
A 1 378 LYS 378 378 378 LYS LYS AAA . n 
A 1 379 PRO 379 379 379 PRO PRO AAA . n 
A 1 380 LEU 380 380 380 LEU LEU AAA . n 
A 1 381 VAL 381 381 381 VAL VAL AAA . n 
A 1 382 GLU 382 382 382 GLU GLU AAA . n 
A 1 383 GLU 383 383 383 GLU GLU AAA . n 
A 1 384 PRO 384 384 384 PRO PRO AAA . n 
A 1 385 GLN 385 385 385 GLN GLN AAA . n 
A 1 386 ASN 386 386 386 ASN ASN AAA . n 
A 1 387 LEU 387 387 387 LEU LEU AAA . n 
A 1 388 ILE 388 388 388 ILE ILE AAA . n 
A 1 389 LYS 389 389 389 LYS LYS AAA . n 
A 1 390 GLN 390 390 390 GLN GLN AAA . n 
A 1 391 ASN 391 391 391 ASN ASN AAA . n 
A 1 392 CYS 392 392 392 CYS CYS AAA . n 
A 1 393 GLU 393 393 393 GLU GLU AAA . n 
A 1 394 LEU 394 394 394 LEU LEU AAA . n 
A 1 395 PHE 395 395 395 PHE PHE AAA . n 
A 1 396 GLU 396 396 396 GLU GLU AAA . n 
A 1 397 GLN 397 397 397 GLN GLN AAA . n 
A 1 398 LEU 398 398 398 LEU LEU AAA . n 
A 1 399 GLY 399 399 399 GLY GLY AAA . n 
A 1 400 GLU 400 400 400 GLU GLU AAA . n 
A 1 401 TYR 401 401 401 TYR TYR AAA . n 
A 1 402 LYS 402 402 402 LYS LYS AAA . n 
A 1 403 PHE 403 403 403 PHE PHE AAA . n 
A 1 404 GLN 404 404 404 GLN GLN AAA . n 
A 1 405 ASN 405 405 405 ASN ASN AAA . n 
A 1 406 ALA 406 406 406 ALA ALA AAA . n 
A 1 407 LEU 407 407 407 LEU LEU AAA . n 
A 1 408 LEU 408 408 408 LEU LEU AAA . n 
A 1 409 VAL 409 409 409 VAL VAL AAA . n 
A 1 410 ARG 410 410 410 ARG ARG AAA . n 
A 1 411 TYR 411 411 411 TYR TYR AAA . n 
A 1 412 THR 412 412 412 THR THR AAA . n 
A 1 413 LYS 413 413 413 LYS LYS AAA . n 
A 1 414 LYS 414 414 414 LYS LYS AAA . n 
A 1 415 VAL 415 415 415 VAL VAL AAA . n 
A 1 416 PRO 416 416 416 PRO PRO AAA . n 
A 1 417 GLN 417 417 417 GLN GLN AAA . n 
A 1 418 VAL 418 418 418 VAL VAL AAA . n 
A 1 419 SER 419 419 419 SER SER AAA . n 
A 1 420 THR 420 420 420 THR THR AAA . n 
A 1 421 PRO 421 421 421 PRO PRO AAA . n 
A 1 422 THR 422 422 422 THR THR AAA . n 
A 1 423 LEU 423 423 423 LEU LEU AAA . n 
A 1 424 VAL 424 424 424 VAL VAL AAA . n 
A 1 425 GLU 425 425 425 GLU GLU AAA . n 
A 1 426 VAL 426 426 426 VAL VAL AAA . n 
A 1 427 SER 427 427 427 SER SER AAA . n 
A 1 428 ARG 428 428 428 ARG ARG AAA . n 
A 1 429 ASN 429 429 429 ASN ASN AAA . n 
A 1 430 LEU 430 430 430 LEU LEU AAA . n 
A 1 431 GLY 431 431 431 GLY GLY AAA . n 
A 1 432 LYS 432 432 432 LYS LYS AAA . n 
A 1 433 VAL 433 433 433 VAL VAL AAA . n 
A 1 434 GLY 434 434 434 GLY GLY AAA . n 
A 1 435 SER 435 435 435 SER SER AAA . n 
A 1 436 LYS 436 436 436 LYS LYS AAA . n 
A 1 437 CYS 437 437 437 CYS CYS AAA . n 
A 1 438 CYS 438 438 438 CYS CYS AAA . n 
A 1 439 LYS 439 439 439 LYS LYS AAA . n 
A 1 440 HIS 440 440 440 HIS HIS AAA . n 
A 1 441 PRO 441 441 441 PRO PRO AAA . n 
A 1 442 GLU 442 442 442 GLU GLU AAA . n 
A 1 443 ALA 443 443 443 ALA ALA AAA . n 
A 1 444 LYS 444 444 444 LYS LYS AAA . n 
A 1 445 ARG 445 445 445 ARG ARG AAA . n 
A 1 446 MET 446 446 446 MET MET AAA . n 
A 1 447 PRO 447 447 447 PRO PRO AAA . n 
A 1 448 CYS 448 448 448 CYS CYS AAA . n 
A 1 449 ALA 449 449 449 ALA ALA AAA . n 
A 1 450 GLU 450 450 450 GLU GLU AAA . n 
A 1 451 ASP 451 451 451 ASP ASP AAA . n 
A 1 452 TYR 452 452 452 TYR TYR AAA . n 
A 1 453 LEU 453 453 453 LEU LEU AAA . n 
A 1 454 SER 454 454 454 SER SER AAA . n 
A 1 455 VAL 455 455 455 VAL VAL AAA . n 
A 1 456 VAL 456 456 456 VAL VAL AAA . n 
A 1 457 LEU 457 457 457 LEU LEU AAA . n 
A 1 458 ASN 458 458 458 ASN ASN AAA . n 
A 1 459 GLN 459 459 459 GLN GLN AAA . n 
A 1 460 LEU 460 460 460 LEU LEU AAA . n 
A 1 461 CYS 461 461 461 CYS CYS AAA . n 
A 1 462 VAL 462 462 462 VAL VAL AAA . n 
A 1 463 LEU 463 463 463 LEU LEU AAA . n 
A 1 464 HIS 464 464 464 HIS HIS AAA . n 
A 1 465 GLU 465 465 465 GLU GLU AAA . n 
A 1 466 LYS 466 466 466 LYS LYS AAA . n 
A 1 467 THR 467 467 467 THR THR AAA . n 
A 1 468 PRO 468 468 468 PRO PRO AAA . n 
A 1 469 VAL 469 469 469 VAL VAL AAA . n 
A 1 470 SER 470 470 470 SER SER AAA . n 
A 1 471 ASP 471 471 471 ASP ASP AAA . n 
A 1 472 ARG 472 472 472 ARG ARG AAA . n 
A 1 473 VAL 473 473 473 VAL VAL AAA . n 
A 1 474 THR 474 474 474 THR THR AAA . n 
A 1 475 LYS 475 475 475 LYS LYS AAA . n 
A 1 476 CYS 476 476 476 CYS CYS AAA . n 
A 1 477 CYS 477 477 477 CYS CYS AAA . n 
A 1 478 THR 478 478 478 THR THR AAA . n 
A 1 479 GLU 479 479 479 GLU GLU AAA . n 
A 1 480 SER 480 480 480 SER SER AAA . n 
A 1 481 LEU 481 481 481 LEU LEU AAA . n 
A 1 482 VAL 482 482 482 VAL VAL AAA . n 
A 1 483 ASN 483 483 483 ASN ASN AAA . n 
A 1 484 ARG 484 484 484 ARG ARG AAA . n 
A 1 485 ARG 485 485 485 ARG ARG AAA . n 
A 1 486 PRO 486 486 486 PRO PRO AAA . n 
A 1 487 CYS 487 487 487 CYS CYS AAA . n 
A 1 488 PHE 488 488 488 PHE PHE AAA . n 
A 1 489 SER 489 489 489 SER SER AAA . n 
A 1 490 ALA 490 490 490 ALA ALA AAA . n 
A 1 491 LEU 491 491 491 LEU LEU AAA . n 
A 1 492 GLU 492 492 492 GLU GLU AAA . n 
A 1 493 VAL 493 493 493 VAL VAL AAA . n 
A 1 494 ASP 494 494 494 ASP ASP AAA . n 
A 1 495 GLU 495 495 495 GLU GLU AAA . n 
A 1 496 THR 496 496 496 THR THR AAA . n 
A 1 497 TYR 497 497 497 TYR TYR AAA . n 
A 1 498 VAL 498 498 498 VAL VAL AAA . n 
A 1 499 PRO 499 499 499 PRO PRO AAA . n 
A 1 500 LYS 500 500 500 LYS LYS AAA . n 
A 1 501 GLU 501 501 501 GLU GLU AAA . n 
A 1 502 PHE 502 502 ?   ?   ?   AAA . n 
A 1 503 ASN 503 503 ?   ?   ?   AAA . n 
A 1 504 ALA 504 504 ?   ?   ?   AAA . n 
A 1 505 GLU 505 505 ?   ?   ?   AAA . n 
A 1 506 THR 506 506 ?   ?   ?   AAA . n 
A 1 507 PHE 507 507 ?   ?   ?   AAA . n 
A 1 508 THR 508 508 ?   ?   ?   AAA . n 
A 1 509 PHE 509 509 ?   ?   ?   AAA . n 
A 1 510 HIS 510 510 ?   ?   ?   AAA . n 
A 1 511 ALA 511 511 ?   ?   ?   AAA . n 
A 1 512 ASP 512 512 ?   ?   ?   AAA . n 
A 1 513 ILE 513 513 513 ILE ILE AAA . n 
A 1 514 CYS 514 514 514 CYS CYS AAA . n 
A 1 515 THR 515 515 515 THR THR AAA . n 
A 1 516 LEU 516 516 516 LEU LEU AAA . n 
A 1 517 SER 517 517 517 SER SER AAA . n 
A 1 518 GLU 518 518 518 GLU GLU AAA . n 
A 1 519 LYS 519 519 519 LYS LYS AAA . n 
A 1 520 GLU 520 520 520 GLU GLU AAA . n 
A 1 521 ARG 521 521 521 ARG ARG AAA . n 
A 1 522 GLN 522 522 522 GLN GLN AAA . n 
A 1 523 ILE 523 523 523 ILE ILE AAA . n 
A 1 524 LYS 524 524 524 LYS LYS AAA . n 
A 1 525 LYS 525 525 525 LYS LYS AAA . n 
A 1 526 GLN 526 526 526 GLN GLN AAA . n 
A 1 527 THR 527 527 527 THR THR AAA . n 
A 1 528 ALA 528 528 528 ALA ALA AAA . n 
A 1 529 LEU 529 529 529 LEU LEU AAA . n 
A 1 530 VAL 530 530 530 VAL VAL AAA . n 
A 1 531 GLU 531 531 531 GLU GLU AAA . n 
A 1 532 LEU 532 532 532 LEU LEU AAA . n 
A 1 533 VAL 533 533 533 VAL VAL AAA . n 
A 1 534 LYS 534 534 534 LYS LYS AAA . n 
A 1 535 HIS 535 535 535 HIS HIS AAA . n 
A 1 536 LYS 536 536 536 LYS LYS AAA . n 
A 1 537 PRO 537 537 537 PRO PRO AAA . n 
A 1 538 LYS 538 538 538 LYS LYS AAA . n 
A 1 539 ALA 539 539 539 ALA ALA AAA . n 
A 1 540 THR 540 540 540 THR THR AAA . n 
A 1 541 LYS 541 541 541 LYS LYS AAA . n 
A 1 542 GLU 542 542 542 GLU GLU AAA . n 
A 1 543 GLN 543 543 543 GLN GLN AAA . n 
A 1 544 LEU 544 544 544 LEU LEU AAA . n 
A 1 545 LYS 545 545 545 LYS LYS AAA . n 
A 1 546 ALA 546 546 546 ALA ALA AAA . n 
A 1 547 VAL 547 547 547 VAL VAL AAA . n 
A 1 548 MET 548 548 548 MET MET AAA . n 
A 1 549 ASP 549 549 549 ASP ASP AAA . n 
A 1 550 ASP 550 550 550 ASP ASP AAA . n 
A 1 551 PHE 551 551 551 PHE PHE AAA . n 
A 1 552 ALA 552 552 552 ALA ALA AAA . n 
A 1 553 ALA 553 553 553 ALA ALA AAA . n 
A 1 554 PHE 554 554 554 PHE PHE AAA . n 
A 1 555 VAL 555 555 555 VAL VAL AAA . n 
A 1 556 GLU 556 556 556 GLU GLU AAA . n 
A 1 557 LYS 557 557 557 LYS LYS AAA . n 
A 1 558 CYS 558 558 558 CYS CYS AAA . n 
A 1 559 CYS 559 559 559 CYS CYS AAA . n 
A 1 560 LYS 560 560 560 LYS LYS AAA . n 
A 1 561 ALA 561 561 561 ALA ALA AAA . n 
A 1 562 ASP 562 562 562 ASP ASP AAA . n 
A 1 563 ASP 563 563 563 ASP ASP AAA . n 
A 1 564 LYS 564 564 564 LYS LYS AAA . n 
A 1 565 GLU 565 565 565 GLU GLU AAA . n 
A 1 566 THR 566 566 566 THR THR AAA . n 
A 1 567 CYS 567 567 567 CYS CYS AAA . n 
A 1 568 PHE 568 568 568 PHE PHE AAA . n 
A 1 569 ALA 569 569 569 ALA ALA AAA . n 
A 1 570 GLU 570 570 570 GLU GLU AAA . n 
A 1 571 GLU 571 571 ?   ?   ?   AAA . n 
A 1 572 GLY 572 572 ?   ?   ?   AAA . n 
A 1 573 LYS 573 573 ?   ?   ?   AAA . n 
A 1 574 LYS 574 574 ?   ?   ?   AAA . n 
A 1 575 LEU 575 575 ?   ?   ?   AAA . n 
A 1 576 VAL 576 576 ?   ?   ?   AAA . n 
A 1 577 ALA 577 577 ?   ?   ?   AAA . n 
A 1 578 ALA 578 578 ?   ?   ?   AAA . n 
A 1 579 SER 579 579 ?   ?   ?   AAA . n 
A 1 580 GLN 580 580 ?   ?   ?   AAA . n 
A 1 581 ALA 581 581 ?   ?   ?   AAA . n 
A 1 582 ALA 582 582 ?   ?   ?   AAA . n 
A 1 583 LEU 583 583 ?   ?   ?   AAA . n 
A 1 584 GLY 584 584 ?   ?   ?   AAA . n 
A 1 585 LEU 585 585 ?   ?   ?   AAA . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        PT 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   PT 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 PT 1 601 1 PT PT AAA . 
C 2 PT 1 602 2 PT PT AAA . 
D 2 PT 1 603 3 PT PT AAA . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 AAA GLN 33  ? CD  ? A GLN 33  CD  
2   1 Y 1 AAA GLN 33  ? OE1 ? A GLN 33  OE1 
3   1 Y 1 AAA GLN 33  ? NE2 ? A GLN 33  NE2 
4   1 Y 1 AAA ASP 56  ? CG  ? A ASP 56  CG  
5   1 Y 1 AAA ASP 56  ? OD1 ? A ASP 56  OD1 
6   1 Y 1 AAA ASP 56  ? OD2 ? A ASP 56  OD2 
7   1 Y 1 AAA GLU 60  ? CG  ? A GLU 60  CG  
8   1 Y 1 AAA GLU 60  ? CD  ? A GLU 60  CD  
9   1 Y 1 AAA GLU 60  ? OE1 ? A GLU 60  OE1 
10  1 Y 1 AAA GLU 60  ? OE2 ? A GLU 60  OE2 
11  1 Y 1 AAA ASP 63  ? CG  ? A ASP 63  CG  
12  1 Y 1 AAA ASP 63  ? OD1 ? A ASP 63  OD1 
13  1 Y 1 AAA ASP 63  ? OD2 ? A ASP 63  OD2 
14  1 Y 1 AAA ASN 111 ? CG  ? A ASN 111 CG  
15  1 Y 1 AAA ASN 111 ? OD1 ? A ASN 111 OD1 
16  1 Y 1 AAA ASN 111 ? ND2 ? A ASN 111 ND2 
17  1 Y 1 AAA ARG 114 ? CG  ? A ARG 114 CG  
18  1 Y 1 AAA ARG 114 ? CD  ? A ARG 114 CD  
19  1 Y 1 AAA ARG 114 ? NE  ? A ARG 114 NE  
20  1 Y 1 AAA ARG 114 ? CZ  ? A ARG 114 CZ  
21  1 Y 1 AAA ARG 114 ? NH1 ? A ARG 114 NH1 
22  1 Y 1 AAA ARG 114 ? NH2 ? A ARG 114 NH2 
23  1 Y 1 AAA GLU 167 ? CG  ? A GLU 167 CG  
24  1 Y 1 AAA GLU 167 ? CD  ? A GLU 167 CD  
25  1 Y 1 AAA GLU 167 ? OE1 ? A GLU 167 OE1 
26  1 Y 1 AAA GLU 167 ? OE2 ? A GLU 167 OE2 
27  1 Y 1 AAA ARG 186 ? CG  ? A ARG 186 CG  
28  1 Y 1 AAA ARG 186 ? CD  ? A ARG 186 CD  
29  1 Y 1 AAA ARG 186 ? NE  ? A ARG 186 NE  
30  1 Y 1 AAA ARG 186 ? CZ  ? A ARG 186 CZ  
31  1 Y 1 AAA ARG 186 ? NH1 ? A ARG 186 NH1 
32  1 Y 1 AAA ARG 186 ? NH2 ? A ARG 186 NH2 
33  1 Y 1 AAA LYS 195 ? CD  ? A LYS 195 CD  
34  1 Y 1 AAA LYS 195 ? CE  ? A LYS 195 CE  
35  1 Y 1 AAA LYS 195 ? NZ  ? A LYS 195 NZ  
36  1 Y 1 AAA ARG 209 ? CD  ? A ARG 209 CD  
37  1 Y 1 AAA ARG 209 ? NE  ? A ARG 209 NE  
38  1 Y 1 AAA ARG 209 ? CZ  ? A ARG 209 CZ  
39  1 Y 1 AAA ARG 209 ? NH1 ? A ARG 209 NH1 
40  1 Y 1 AAA ARG 209 ? NH2 ? A ARG 209 NH2 
41  1 Y 1 AAA LYS 276 ? CG  ? A LYS 276 CG  
42  1 Y 1 AAA LYS 276 ? CD  ? A LYS 276 CD  
43  1 Y 1 AAA LYS 276 ? CE  ? A LYS 276 CE  
44  1 Y 1 AAA LYS 276 ? NZ  ? A LYS 276 NZ  
45  1 Y 1 AAA GLU 277 ? CG  ? A GLU 277 CG  
46  1 Y 1 AAA GLU 277 ? CD  ? A GLU 277 CD  
47  1 Y 1 AAA GLU 277 ? OE1 ? A GLU 277 OE1 
48  1 Y 1 AAA GLU 277 ? OE2 ? A GLU 277 OE2 
49  1 Y 1 AAA GLU 280 ? CG  ? A GLU 280 CG  
50  1 Y 1 AAA GLU 280 ? CD  ? A GLU 280 CD  
51  1 Y 1 AAA GLU 280 ? OE1 ? A GLU 280 OE1 
52  1 Y 1 AAA GLU 280 ? OE2 ? A GLU 280 OE2 
53  1 Y 1 AAA GLU 294 ? CG  ? A GLU 294 CG  
54  1 Y 1 AAA GLU 294 ? CD  ? A GLU 294 CD  
55  1 Y 1 AAA GLU 294 ? OE1 ? A GLU 294 OE1 
56  1 Y 1 AAA GLU 294 ? OE2 ? A GLU 294 OE2 
57  1 Y 1 AAA GLU 297 ? CG  ? A GLU 297 CG  
58  1 Y 1 AAA GLU 297 ? CD  ? A GLU 297 CD  
59  1 Y 1 AAA GLU 297 ? OE1 ? A GLU 297 OE1 
60  1 Y 1 AAA GLU 297 ? OE2 ? A GLU 297 OE2 
61  1 Y 1 AAA LYS 313 ? CG  ? A LYS 313 CG  
62  1 Y 1 AAA LYS 313 ? CD  ? A LYS 313 CD  
63  1 Y 1 AAA LYS 313 ? CE  ? A LYS 313 CE  
64  1 Y 1 AAA LYS 313 ? NZ  ? A LYS 313 NZ  
65  1 Y 1 AAA LYS 359 ? CG  ? A LYS 359 CG  
66  1 Y 1 AAA LYS 359 ? CD  ? A LYS 359 CD  
67  1 Y 1 AAA LYS 359 ? CE  ? A LYS 359 CE  
68  1 Y 1 AAA LYS 359 ? NZ  ? A LYS 359 NZ  
69  1 Y 1 AAA LYS 372 ? CD  ? A LYS 372 CD  
70  1 Y 1 AAA LYS 372 ? CE  ? A LYS 372 CE  
71  1 Y 1 AAA LYS 372 ? NZ  ? A LYS 372 NZ  
72  1 Y 1 AAA LYS 378 ? CG  ? A LYS 378 CG  
73  1 Y 1 AAA LYS 378 ? CD  ? A LYS 378 CD  
74  1 Y 1 AAA LYS 378 ? CE  ? A LYS 378 CE  
75  1 Y 1 AAA LYS 378 ? NZ  ? A LYS 378 NZ  
76  1 Y 1 AAA LYS 389 ? CD  ? A LYS 389 CD  
77  1 Y 1 AAA LYS 389 ? CE  ? A LYS 389 CE  
78  1 Y 1 AAA LYS 389 ? NZ  ? A LYS 389 NZ  
79  1 Y 1 AAA LYS 402 ? CG  ? A LYS 402 CG  
80  1 Y 1 AAA LYS 402 ? CD  ? A LYS 402 CD  
81  1 Y 1 AAA LYS 402 ? CE  ? A LYS 402 CE  
82  1 Y 1 AAA LYS 402 ? NZ  ? A LYS 402 NZ  
83  1 Y 1 AAA LYS 436 ? CD  ? A LYS 436 CD  
84  1 Y 1 AAA LYS 436 ? CE  ? A LYS 436 CE  
85  1 Y 1 AAA LYS 436 ? NZ  ? A LYS 436 NZ  
86  1 Y 1 AAA GLU 442 ? CG  ? A GLU 442 CG  
87  1 Y 1 AAA GLU 442 ? CD  ? A GLU 442 CD  
88  1 Y 1 AAA GLU 442 ? OE1 ? A GLU 442 OE1 
89  1 Y 1 AAA GLU 442 ? OE2 ? A GLU 442 OE2 
90  1 Y 1 AAA LYS 466 ? CG  ? A LYS 466 CG  
91  1 Y 1 AAA LYS 466 ? CD  ? A LYS 466 CD  
92  1 Y 1 AAA LYS 466 ? CE  ? A LYS 466 CE  
93  1 Y 1 AAA LYS 466 ? NZ  ? A LYS 466 NZ  
94  1 Y 1 AAA GLU 495 ? CG  ? A GLU 495 CG  
95  1 Y 1 AAA GLU 495 ? CD  ? A GLU 495 CD  
96  1 Y 1 AAA GLU 495 ? OE1 ? A GLU 495 OE1 
97  1 Y 1 AAA GLU 495 ? OE2 ? A GLU 495 OE2 
98  1 Y 1 AAA GLU 501 ? CB  ? A GLU 501 CB  
99  1 Y 1 AAA GLU 501 ? CG  ? A GLU 501 CG  
100 1 Y 1 AAA GLU 501 ? CD  ? A GLU 501 CD  
101 1 Y 1 AAA GLU 501 ? OE1 ? A GLU 501 OE1 
102 1 Y 1 AAA GLU 501 ? OE2 ? A GLU 501 OE2 
103 1 Y 1 AAA LYS 519 ? CG  ? A LYS 519 CG  
104 1 Y 1 AAA LYS 519 ? CD  ? A LYS 519 CD  
105 1 Y 1 AAA LYS 519 ? CE  ? A LYS 519 CE  
106 1 Y 1 AAA LYS 519 ? NZ  ? A LYS 519 NZ  
107 1 Y 1 AAA LYS 536 ? CG  ? A LYS 536 CG  
108 1 Y 1 AAA LYS 536 ? CD  ? A LYS 536 CD  
109 1 Y 1 AAA LYS 536 ? CE  ? A LYS 536 CE  
110 1 Y 1 AAA LYS 536 ? NZ  ? A LYS 536 NZ  
111 1 Y 1 AAA LYS 538 ? CG  ? A LYS 538 CG  
112 1 Y 1 AAA LYS 538 ? CD  ? A LYS 538 CD  
113 1 Y 1 AAA LYS 538 ? CE  ? A LYS 538 CE  
114 1 Y 1 AAA LYS 538 ? NZ  ? A LYS 538 NZ  
115 1 Y 1 AAA LYS 541 ? CG  ? A LYS 541 CG  
116 1 Y 1 AAA LYS 541 ? CD  ? A LYS 541 CD  
117 1 Y 1 AAA LYS 541 ? CE  ? A LYS 541 CE  
118 1 Y 1 AAA LYS 541 ? NZ  ? A LYS 541 NZ  
119 1 Y 1 AAA LYS 545 ? CG  ? A LYS 545 CG  
120 1 Y 1 AAA LYS 545 ? CD  ? A LYS 545 CD  
121 1 Y 1 AAA LYS 545 ? CE  ? A LYS 545 CE  
122 1 Y 1 AAA LYS 545 ? NZ  ? A LYS 545 NZ  
123 1 Y 1 AAA ASP 550 ? CG  ? A ASP 550 CG  
124 1 Y 1 AAA ASP 550 ? OD1 ? A ASP 550 OD1 
125 1 Y 1 AAA ASP 550 ? OD2 ? A ASP 550 OD2 
126 1 Y 1 AAA GLU 556 ? CG  ? A GLU 556 CG  
127 1 Y 1 AAA GLU 556 ? CD  ? A GLU 556 CD  
128 1 Y 1 AAA GLU 556 ? OE1 ? A GLU 556 OE1 
129 1 Y 1 AAA GLU 556 ? OE2 ? A GLU 556 OE2 
130 1 Y 1 AAA LYS 560 ? CG  ? A LYS 560 CG  
131 1 Y 1 AAA LYS 560 ? CD  ? A LYS 560 CD  
132 1 Y 1 AAA LYS 560 ? CE  ? A LYS 560 CE  
133 1 Y 1 AAA LYS 560 ? NZ  ? A LYS 560 NZ  
134 1 Y 1 AAA ASP 562 ? CG  ? A ASP 562 CG  
135 1 Y 1 AAA ASP 562 ? OD1 ? A ASP 562 OD1 
136 1 Y 1 AAA ASP 562 ? OD2 ? A ASP 562 OD2 
137 1 Y 1 AAA ASP 563 ? CG  ? A ASP 563 CG  
138 1 Y 1 AAA ASP 563 ? OD1 ? A ASP 563 OD1 
139 1 Y 1 AAA ASP 563 ? OD2 ? A ASP 563 OD2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC   ? ? ? 5.8.0258 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? autoPROC ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? autoPROC ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .        4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   102.548 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9HNB 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     58.070 
_cell.length_a_esd                 ? 
_cell.length_b                     86.550 
_cell.length_b_esd                 ? 
_cell.length_c                     59.500 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        2 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9HNB 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9HNB 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.19 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          43.90 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '25-30% PEG3350 -50 mM potassium phosphate buffer pH 7.5' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-12-05 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.00 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ELETTRA BEAMLINE 11.2C' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.00 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   11.2C 
_diffrn_source.pdbx_synchrotron_site       ELETTRA 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9HNB 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              3.90 
_reflns.d_resolution_low                               47.42 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     5252 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                3.4 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.3 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.986 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.139 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    3.90 
_reflns_shell.d_res_low                                     3.97 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.5 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             260 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               3.5 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               1.097 
_reflns_shell.pdbx_Rpim_I_all                               0.573 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.568 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          99.6 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.929 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -1.282 
_refine.aniso_B[1][2]                            -0.000 
_refine.aniso_B[1][3]                            1.783 
_refine.aniso_B[2][2]                            -0.810 
_refine.aniso_B[2][3]                            -0.000 
_refine.aniso_B[3][3]                            1.181 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               112.871 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.845 
_refine.correlation_coeff_Fo_to_Fc_free          0.830 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9HNB 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.900 
_refine.ls_d_res_low                             47.42 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     4966 
_refine.ls_number_reflns_R_free                  263 
_refine.ls_number_reflns_R_work                  4703 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    93.363 
_refine.ls_percent_reflns_R_free                 5.296 
_refine.ls_R_factor_all                          0.293 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.3275 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2917 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  1.257 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             89.719 
_refine.overall_SU_ML                            1.224 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        4195 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         3 
_refine_hist.number_atoms_solvent             0 
_refine_hist.number_atoms_total               4198 
_refine_hist.d_res_high                       3.900 
_refine_hist.d_res_low                        47.42 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.009  0.013   4294  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.017   3906  ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 0.004  0.010   8189  ? r_ext_dist_refined_d           ? ? 
'X-RAY DIFFRACTION' ? 1.502  1.648   5827  ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 1.597  1.576   9074  ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 6.009  5.000   540   ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 34.923 23.333  210   ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.189 15.000  727   ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 18.743 15.000  20    ? r_dihedral_angle_4_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.100  0.200   565   ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.005  0.020   4790  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020   858   ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.275  0.200   1209  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.183  0.200   3718  ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.185  0.200   2153  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.083  0.200   2085  ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.174  0.200   64    ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.174  0.200   12    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.228  0.200   17    ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.445  0.200   1     ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 5.757  12.279  2169  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 5.733  12.274  2168  ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 9.839  18.410  2706  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 9.842  18.415  2707  ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 5.218  12.661  2125  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 5.218  12.655  2123  ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 9.175  18.824  3121  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 9.174  18.824  3121  ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 17.921 254.120 10469 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 17.918 254.106 10469 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 3.900  4.001  . . 22 274 77.6903  . . . . 0.317 . . . . . . . . . . . 0.396 
'X-RAY DIFFRACTION' 4.001  4.110  . . 13 280 80.2740  . . . . 0.301 . . . . . . . . . . . 0.418 
'X-RAY DIFFRACTION' 4.110  4.228  . . 13 305 84.5745  . . . . 0.287 . . . . . . . . . . . 0.422 
'X-RAY DIFFRACTION' 4.228  4.358  . . 19 308 87.4332  . . . . 0.281 . . . . . . . . . . . 0.272 
'X-RAY DIFFRACTION' 4.358  4.500  . . 15 294 91.9643  . . . . 0.246 . . . . . . . . . . . 0.406 
'X-RAY DIFFRACTION' 4.500  4.657  . . 15 298 93.7126  . . . . 0.258 . . . . . . . . . . . 0.399 
'X-RAY DIFFRACTION' 4.657  4.831  . . 22 314 99.7033  . . . . 0.232 . . . . . . . . . . . 0.310 
'X-RAY DIFFRACTION' 4.831  5.027  . . 25 279 99.0228  . . . . 0.264 . . . . . . . . . . . 0.268 
'X-RAY DIFFRACTION' 5.027  5.249  . . 17 288 100.0000 . . . . 0.230 . . . . . . . . . . . 0.249 
'X-RAY DIFFRACTION' 5.249  5.503  . . 6  279 100.0000 . . . . 0.278 . . . . . . . . . . . 0.414 
'X-RAY DIFFRACTION' 5.503  5.798  . . 15 261 98.9247  . . . . 0.314 . . . . . . . . . . . 0.325 
'X-RAY DIFFRACTION' 5.798  6.146  . . 19 230 97.6471  . . . . 0.320 . . . . . . . . . . . 0.447 
'X-RAY DIFFRACTION' 6.146  6.565  . . 10 240 99.2063  . . . . 0.315 . . . . . . . . . . . 0.348 
'X-RAY DIFFRACTION' 6.565  7.083  . . 12 208 99.0991  . . . . 0.301 . . . . . . . . . . . 0.336 
'X-RAY DIFFRACTION' 7.083  7.748  . . 10 194 99.0291  . . . . 0.271 . . . . . . . . . . . 0.376 
'X-RAY DIFFRACTION' 7.748  8.643  . . 11 187 99.0000  . . . . 0.265 . . . . . . . . . . . 0.284 
'X-RAY DIFFRACTION' 8.643  9.943  . . 8  152 95.8084  . . . . 0.268 . . . . . . . . . . . 0.286 
'X-RAY DIFFRACTION' 9.943  12.090 . . 4  142 97.9866  . . . . 0.300 . . . . . . . . . . . 0.067 
'X-RAY DIFFRACTION' 12.090 16.739 . . 5  105 97.3451  . . . . 0.379 . . . . . . . . . . . 0.399 
# 
_struct.entry_id                     9HNB 
_struct.title                        
'X-ray structure of the adduct formed upon reaction of the diiodido analogue of picoplatin with human serum albumin' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9HNB 
_struct_keywords.text            'platin, interaction, metallodrug, picoplatin, diiodido analogue, albumin, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    ALBU_HUMAN 
_struct_ref.pdbx_db_accession          P02768 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;DAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATL
RETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKR
YKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTK
VHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYA
EAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGE
YKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTES
LVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCK
ADDKETCFAEEGKKLVAASQAALGL
;
_struct_ref.pdbx_align_begin           25 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9HNB 
_struct_ref_seq.pdbx_strand_id                AAA 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 585 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P02768 
_struct_ref_seq.db_align_beg                  25 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  609 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       585 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 380   ? 
1 MORE         -52   ? 
1 'SSA (A^2)'  26280 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLU A 6   ? LEU A 31  ? GLU AAA 6   LEU AAA 31  1 ? 26 
HELX_P HELX_P2  AA2 PRO A 35  ? ASP A 56  ? PRO AAA 35  ASP AAA 56  1 ? 22 
HELX_P HELX_P3  AA3 SER A 65  ? CYS A 75  ? SER AAA 65  CYS AAA 75  1 ? 11 
HELX_P HELX_P4  AA4 PRO A 96  ? HIS A 105 ? PRO AAA 96  HIS AAA 105 1 ? 10 
HELX_P HELX_P5  AA5 GLU A 119 ? ASN A 130 ? GLU AAA 119 ASN AAA 130 1 ? 12 
HELX_P HELX_P6  AA6 ASN A 130 ? HIS A 146 ? ASN AAA 130 HIS AAA 146 1 ? 17 
HELX_P HELX_P7  AA7 TYR A 150 ? CYS A 169 ? TYR AAA 150 CYS AAA 169 1 ? 20 
HELX_P HELX_P8  AA8 CYS A 177 ? GLY A 207 ? CYS AAA 177 GLY AAA 207 1 ? 31 
HELX_P HELX_P9  AA9 GLY A 207 ? PHE A 223 ? GLY AAA 207 PHE AAA 223 1 ? 17 
HELX_P HELX_P10 AB1 GLU A 227 ? GLY A 248 ? GLU AAA 227 GLY AAA 248 1 ? 22 
HELX_P HELX_P11 AB2 ASP A 249 ? GLN A 268 ? ASP AAA 249 GLN AAA 268 1 ? 20 
HELX_P HELX_P12 AB3 ASP A 269 ? ILE A 271 ? ASP AAA 269 ILE AAA 271 5 ? 3  
HELX_P HELX_P13 AB4 LYS A 274 ? GLU A 280 ? LYS AAA 274 GLU AAA 280 1 ? 7  
HELX_P HELX_P14 AB5 PRO A 282 ? VAL A 293 ? PRO AAA 282 VAL AAA 293 1 ? 12 
HELX_P HELX_P15 AB6 LEU A 305 ? VAL A 310 ? LEU AAA 305 VAL AAA 310 1 ? 6  
HELX_P HELX_P16 AB7 ASP A 314 ? ARG A 337 ? ASP AAA 314 ARG AAA 337 1 ? 24 
HELX_P HELX_P17 AB8 SER A 342 ? CYS A 361 ? SER AAA 342 CYS AAA 361 1 ? 20 
HELX_P HELX_P18 AB9 ASP A 365 ? ALA A 371 ? ASP AAA 365 ALA AAA 371 1 ? 7  
HELX_P HELX_P19 AC1 GLU A 376 ? GLY A 399 ? GLU AAA 376 GLY AAA 399 1 ? 24 
HELX_P HELX_P20 AC2 GLY A 399 ? VAL A 415 ? GLY AAA 399 VAL AAA 415 1 ? 17 
HELX_P HELX_P21 AC3 SER A 419 ? CYS A 438 ? SER AAA 419 CYS AAA 438 1 ? 20 
HELX_P HELX_P22 AC4 PRO A 441 ? THR A 467 ? PRO AAA 441 THR AAA 467 1 ? 27 
HELX_P HELX_P23 AC5 SER A 470 ? SER A 480 ? SER AAA 470 SER AAA 480 1 ? 11 
HELX_P HELX_P24 AC6 ASN A 483 ? LEU A 491 ? ASN AAA 483 LEU AAA 491 1 ? 9  
HELX_P HELX_P25 AC7 SER A 517 ? LYS A 536 ? SER AAA 517 LYS AAA 536 1 ? 20 
HELX_P HELX_P26 AC8 THR A 540 ? ALA A 561 ? THR AAA 540 ALA AAA 561 1 ? 22 
HELX_P HELX_P27 AC9 ASP A 563 ? ALA A 569 ? ASP AAA 563 ALA AAA 569 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ? ? A CYS 53  SG  ? ? ? 1_555 A CYS 62  SG ? ? AAA CYS 53  AAA CYS 62  1_555 ? ? ? ? ? ? ? 2.027 ? ? 
disulf2  disulf ? ? A CYS 75  SG  ? ? ? 1_555 A CYS 91  SG ? ? AAA CYS 75  AAA CYS 91  1_555 ? ? ? ? ? ? ? 2.034 ? ? 
disulf3  disulf ? ? A CYS 90  SG  ? ? ? 1_555 A CYS 101 SG ? ? AAA CYS 90  AAA CYS 101 1_555 ? ? ? ? ? ? ? 2.045 ? ? 
disulf4  disulf ? ? A CYS 124 SG  ? ? ? 1_555 A CYS 169 SG ? ? AAA CYS 124 AAA CYS 169 1_555 ? ? ? ? ? ? ? 2.039 ? ? 
disulf5  disulf ? ? A CYS 168 SG  ? ? ? 1_555 A CYS 177 SG ? ? AAA CYS 168 AAA CYS 177 1_555 ? ? ? ? ? ? ? 2.046 ? ? 
disulf6  disulf ? ? A CYS 200 SG  ? ? ? 1_555 A CYS 246 SG ? ? AAA CYS 200 AAA CYS 246 1_555 ? ? ? ? ? ? ? 2.039 ? ? 
disulf7  disulf ? ? A CYS 245 SG  ? ? ? 1_555 A CYS 253 SG ? ? AAA CYS 245 AAA CYS 253 1_555 ? ? ? ? ? ? ? 2.022 ? ? 
disulf8  disulf ? ? A CYS 265 SG  ? ? ? 1_555 A CYS 279 SG ? ? AAA CYS 265 AAA CYS 279 1_555 ? ? ? ? ? ? ? 2.037 ? ? 
disulf9  disulf ? ? A CYS 278 SG  ? ? ? 1_555 A CYS 289 SG ? ? AAA CYS 278 AAA CYS 289 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf10 disulf ? ? A CYS 316 SG  ? ? ? 1_555 A CYS 361 SG ? ? AAA CYS 316 AAA CYS 361 1_555 ? ? ? ? ? ? ? 2.048 ? ? 
disulf11 disulf ? ? A CYS 360 SG  ? ? ? 1_555 A CYS 369 SG ? ? AAA CYS 360 AAA CYS 369 1_555 ? ? ? ? ? ? ? 2.040 ? ? 
disulf12 disulf ? ? A CYS 392 SG  ? ? ? 1_555 A CYS 438 SG ? ? AAA CYS 392 AAA CYS 438 1_555 ? ? ? ? ? ? ? 2.054 ? ? 
disulf13 disulf ? ? A CYS 437 SG  ? ? ? 1_555 A CYS 448 SG ? ? AAA CYS 437 AAA CYS 448 1_555 ? ? ? ? ? ? ? 2.038 ? ? 
disulf14 disulf ? ? A CYS 461 SG  ? ? ? 1_555 A CYS 477 SG ? ? AAA CYS 461 AAA CYS 477 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf15 disulf ? ? A CYS 476 SG  ? ? ? 1_555 A CYS 487 SG ? ? AAA CYS 476 AAA CYS 487 1_555 ? ? ? ? ? ? ? 2.050 ? ? 
disulf16 disulf ? ? A CYS 514 SG  ? ? ? 1_555 A CYS 559 SG ? ? AAA CYS 514 AAA CYS 559 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf17 disulf ? ? A CYS 558 SG  ? ? ? 1_555 A CYS 567 SG ? ? AAA CYS 558 AAA CYS 567 1_555 ? ? ? ? ? ? ? 2.054 ? ? 
metalc1  metalc ? ? A HIS 146 NE2 ? ? ? 1_555 B PT  .   PT ? ? AAA HIS 146 AAA PT  601 1_555 ? ? ? ? ? ? ? 2.356 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
metalc ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  CYS A 53  ? CYS A 62  ? CYS AAA 53  ? 1_555 CYS AAA 62  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2  CYS A 75  ? CYS A 91  ? CYS AAA 75  ? 1_555 CYS AAA 91  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3  CYS A 90  ? CYS A 101 ? CYS AAA 90  ? 1_555 CYS AAA 101 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4  CYS A 124 ? CYS A 169 ? CYS AAA 124 ? 1_555 CYS AAA 169 ? 1_555 SG SG . . . None 'Disulfide bridge' 
5  CYS A 168 ? CYS A 177 ? CYS AAA 168 ? 1_555 CYS AAA 177 ? 1_555 SG SG . . . None 'Disulfide bridge' 
6  CYS A 200 ? CYS A 246 ? CYS AAA 200 ? 1_555 CYS AAA 246 ? 1_555 SG SG . . . None 'Disulfide bridge' 
7  CYS A 245 ? CYS A 253 ? CYS AAA 245 ? 1_555 CYS AAA 253 ? 1_555 SG SG . . . None 'Disulfide bridge' 
8  CYS A 265 ? CYS A 279 ? CYS AAA 265 ? 1_555 CYS AAA 279 ? 1_555 SG SG . . . None 'Disulfide bridge' 
9  CYS A 278 ? CYS A 289 ? CYS AAA 278 ? 1_555 CYS AAA 289 ? 1_555 SG SG . . . None 'Disulfide bridge' 
10 CYS A 316 ? CYS A 361 ? CYS AAA 316 ? 1_555 CYS AAA 361 ? 1_555 SG SG . . . None 'Disulfide bridge' 
11 CYS A 360 ? CYS A 369 ? CYS AAA 360 ? 1_555 CYS AAA 369 ? 1_555 SG SG . . . None 'Disulfide bridge' 
12 CYS A 392 ? CYS A 438 ? CYS AAA 392 ? 1_555 CYS AAA 438 ? 1_555 SG SG . . . None 'Disulfide bridge' 
13 CYS A 437 ? CYS A 448 ? CYS AAA 437 ? 1_555 CYS AAA 448 ? 1_555 SG SG . . . None 'Disulfide bridge' 
14 CYS A 461 ? CYS A 477 ? CYS AAA 461 ? 1_555 CYS AAA 477 ? 1_555 SG SG . . . None 'Disulfide bridge' 
15 CYS A 476 ? CYS A 487 ? CYS AAA 476 ? 1_555 CYS AAA 487 ? 1_555 SG SG . . . None 'Disulfide bridge' 
16 CYS A 514 ? CYS A 559 ? CYS AAA 514 ? 1_555 CYS AAA 559 ? 1_555 SG SG . . . None 'Disulfide bridge' 
17 CYS A 558 ? CYS A 567 ? CYS AAA 558 ? 1_555 CYS AAA 567 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          GLU 
_struct_mon_prot_cis.label_seq_id           95 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           GLU 
_struct_mon_prot_cis.auth_seq_id            95 
_struct_mon_prot_cis.auth_asym_id           AAA 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    96 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     96 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    AAA 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -4.38 
# 
_pdbx_entry_details.entry_id                   9HNB 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   SD 
_pdbx_validate_close_contact.auth_asym_id_1   AAA 
_pdbx_validate_close_contact.auth_comp_id_1   MET 
_pdbx_validate_close_contact.auth_seq_id_1    298 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   PT 
_pdbx_validate_close_contact.auth_asym_id_2   AAA 
_pdbx_validate_close_contact.auth_comp_id_2   PT 
_pdbx_validate_close_contact.auth_seq_id_2    603 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             1.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER AAA 58  ? ? -105.96 40.35   
2  1 ASN AAA 61  ? ? 70.15   -2.68   
3  1 ASN AAA 111 ? ? -75.36  35.35   
4  1 TYR AAA 150 ? ? -67.28  95.82   
5  1 GLU AAA 167 ? ? -57.49  -74.74  
6  1 CYS AAA 169 ? ? -81.66  35.15   
7  1 GLN AAA 170 ? ? -166.97 58.73   
8  1 CYS AAA 177 ? ? -102.81 -72.45  
9  1 ASP AAA 249 ? ? -111.41 55.63   
10 1 GLN AAA 268 ? ? -16.20  -58.69  
11 1 ILE AAA 271 ? ? -125.48 -60.79  
12 1 VAL AAA 293 ? ? -40.85  154.85  
13 1 ALA AAA 300 ? ? -67.56  -92.43  
14 1 ALA AAA 306 ? ? -29.89  -43.67  
15 1 VAL AAA 310 ? ? -143.29 -54.23  
16 1 ALA AAA 322 ? ? -165.43 69.11   
17 1 PRO AAA 416 ? ? -57.88  -7.19   
18 1 THR AAA 515 ? ? -99.51  51.28   
19 1 LYS AAA 538 ? ? -78.48  49.37   
20 1 ALA AAA 561 ? ? 111.61  179.44  
21 1 ASP AAA 562 ? ? 145.71  -100.80 
22 1 LYS AAA 564 ? ? -23.10  -53.64  
23 1 ALA AAA 569 ? ? -47.37  75.67   
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 AAA ASP 1   ? A ASP 1   
2  1 Y 1 AAA ALA 2   ? A ALA 2   
3  1 Y 1 AAA HIS 3   ? A HIS 3   
4  1 Y 1 AAA LYS 4   ? A LYS 4   
5  1 Y 1 AAA VAL 77  ? A VAL 77  
6  1 Y 1 AAA ALA 78  ? A ALA 78  
7  1 Y 1 AAA THR 79  ? A THR 79  
8  1 Y 1 AAA LEU 80  ? A LEU 80  
9  1 Y 1 AAA ARG 81  ? A ARG 81  
10 1 Y 1 AAA GLU 82  ? A GLU 82  
11 1 Y 1 AAA THR 83  ? A THR 83  
12 1 Y 1 AAA TYR 84  ? A TYR 84  
13 1 Y 1 AAA GLY 85  ? A GLY 85  
14 1 Y 1 AAA GLU 86  ? A GLU 86  
15 1 Y 1 AAA MET 87  ? A MET 87  
16 1 Y 1 AAA ALA 88  ? A ALA 88  
17 1 Y 1 AAA PHE 502 ? A PHE 502 
18 1 Y 1 AAA ASN 503 ? A ASN 503 
19 1 Y 1 AAA ALA 504 ? A ALA 504 
20 1 Y 1 AAA GLU 505 ? A GLU 505 
21 1 Y 1 AAA THR 506 ? A THR 506 
22 1 Y 1 AAA PHE 507 ? A PHE 507 
23 1 Y 1 AAA THR 508 ? A THR 508 
24 1 Y 1 AAA PHE 509 ? A PHE 509 
25 1 Y 1 AAA HIS 510 ? A HIS 510 
26 1 Y 1 AAA ALA 511 ? A ALA 511 
27 1 Y 1 AAA ASP 512 ? A ASP 512 
28 1 Y 1 AAA GLU 571 ? A GLU 571 
29 1 Y 1 AAA GLY 572 ? A GLY 572 
30 1 Y 1 AAA LYS 573 ? A LYS 573 
31 1 Y 1 AAA LYS 574 ? A LYS 574 
32 1 Y 1 AAA LEU 575 ? A LEU 575 
33 1 Y 1 AAA VAL 576 ? A VAL 576 
34 1 Y 1 AAA ALA 577 ? A ALA 577 
35 1 Y 1 AAA ALA 578 ? A ALA 578 
36 1 Y 1 AAA SER 579 ? A SER 579 
37 1 Y 1 AAA GLN 580 ? A GLN 580 
38 1 Y 1 AAA ALA 581 ? A ALA 581 
39 1 Y 1 AAA ALA 582 ? A ALA 582 
40 1 Y 1 AAA LEU 583 ? A LEU 583 
41 1 Y 1 AAA GLY 584 ? A GLY 584 
42 1 Y 1 AAA LEU 585 ? A LEU 585 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
ILE N    N  N N 158 
ILE CA   C  N S 159 
ILE C    C  N N 160 
ILE O    O  N N 161 
ILE CB   C  N S 162 
ILE CG1  C  N N 163 
ILE CG2  C  N N 164 
ILE CD1  C  N N 165 
ILE OXT  O  N N 166 
ILE H    H  N N 167 
ILE H2   H  N N 168 
ILE HA   H  N N 169 
ILE HB   H  N N 170 
ILE HG12 H  N N 171 
ILE HG13 H  N N 172 
ILE HG21 H  N N 173 
ILE HG22 H  N N 174 
ILE HG23 H  N N 175 
ILE HD11 H  N N 176 
ILE HD12 H  N N 177 
ILE HD13 H  N N 178 
ILE HXT  H  N N 179 
LEU N    N  N N 180 
LEU CA   C  N S 181 
LEU C    C  N N 182 
LEU O    O  N N 183 
LEU CB   C  N N 184 
LEU CG   C  N N 185 
LEU CD1  C  N N 186 
LEU CD2  C  N N 187 
LEU OXT  O  N N 188 
LEU H    H  N N 189 
LEU H2   H  N N 190 
LEU HA   H  N N 191 
LEU HB2  H  N N 192 
LEU HB3  H  N N 193 
LEU HG   H  N N 194 
LEU HD11 H  N N 195 
LEU HD12 H  N N 196 
LEU HD13 H  N N 197 
LEU HD21 H  N N 198 
LEU HD22 H  N N 199 
LEU HD23 H  N N 200 
LEU HXT  H  N N 201 
LYS N    N  N N 202 
LYS CA   C  N S 203 
LYS C    C  N N 204 
LYS O    O  N N 205 
LYS CB   C  N N 206 
LYS CG   C  N N 207 
LYS CD   C  N N 208 
LYS CE   C  N N 209 
LYS NZ   N  N N 210 
LYS OXT  O  N N 211 
LYS H    H  N N 212 
LYS H2   H  N N 213 
LYS HA   H  N N 214 
LYS HB2  H  N N 215 
LYS HB3  H  N N 216 
LYS HG2  H  N N 217 
LYS HG3  H  N N 218 
LYS HD2  H  N N 219 
LYS HD3  H  N N 220 
LYS HE2  H  N N 221 
LYS HE3  H  N N 222 
LYS HZ1  H  N N 223 
LYS HZ2  H  N N 224 
LYS HZ3  H  N N 225 
LYS HXT  H  N N 226 
MET N    N  N N 227 
MET CA   C  N S 228 
MET C    C  N N 229 
MET O    O  N N 230 
MET CB   C  N N 231 
MET CG   C  N N 232 
MET SD   S  N N 233 
MET CE   C  N N 234 
MET OXT  O  N N 235 
MET H    H  N N 236 
MET H2   H  N N 237 
MET HA   H  N N 238 
MET HB2  H  N N 239 
MET HB3  H  N N 240 
MET HG2  H  N N 241 
MET HG3  H  N N 242 
MET HE1  H  N N 243 
MET HE2  H  N N 244 
MET HE3  H  N N 245 
MET HXT  H  N N 246 
PHE N    N  N N 247 
PHE CA   C  N S 248 
PHE C    C  N N 249 
PHE O    O  N N 250 
PHE CB   C  N N 251 
PHE CG   C  Y N 252 
PHE CD1  C  Y N 253 
PHE CD2  C  Y N 254 
PHE CE1  C  Y N 255 
PHE CE2  C  Y N 256 
PHE CZ   C  Y N 257 
PHE OXT  O  N N 258 
PHE H    H  N N 259 
PHE H2   H  N N 260 
PHE HA   H  N N 261 
PHE HB2  H  N N 262 
PHE HB3  H  N N 263 
PHE HD1  H  N N 264 
PHE HD2  H  N N 265 
PHE HE1  H  N N 266 
PHE HE2  H  N N 267 
PHE HZ   H  N N 268 
PHE HXT  H  N N 269 
PRO N    N  N N 270 
PRO CA   C  N S 271 
PRO C    C  N N 272 
PRO O    O  N N 273 
PRO CB   C  N N 274 
PRO CG   C  N N 275 
PRO CD   C  N N 276 
PRO OXT  O  N N 277 
PRO H    H  N N 278 
PRO HA   H  N N 279 
PRO HB2  H  N N 280 
PRO HB3  H  N N 281 
PRO HG2  H  N N 282 
PRO HG3  H  N N 283 
PRO HD2  H  N N 284 
PRO HD3  H  N N 285 
PRO HXT  H  N N 286 
PT  PT   PT N N 287 
SER N    N  N N 288 
SER CA   C  N S 289 
SER C    C  N N 290 
SER O    O  N N 291 
SER CB   C  N N 292 
SER OG   O  N N 293 
SER OXT  O  N N 294 
SER H    H  N N 295 
SER H2   H  N N 296 
SER HA   H  N N 297 
SER HB2  H  N N 298 
SER HB3  H  N N 299 
SER HG   H  N N 300 
SER HXT  H  N N 301 
THR N    N  N N 302 
THR CA   C  N S 303 
THR C    C  N N 304 
THR O    O  N N 305 
THR CB   C  N R 306 
THR OG1  O  N N 307 
THR CG2  C  N N 308 
THR OXT  O  N N 309 
THR H    H  N N 310 
THR H2   H  N N 311 
THR HA   H  N N 312 
THR HB   H  N N 313 
THR HG1  H  N N 314 
THR HG21 H  N N 315 
THR HG22 H  N N 316 
THR HG23 H  N N 317 
THR HXT  H  N N 318 
TRP N    N  N N 319 
TRP CA   C  N S 320 
TRP C    C  N N 321 
TRP O    O  N N 322 
TRP CB   C  N N 323 
TRP CG   C  Y N 324 
TRP CD1  C  Y N 325 
TRP CD2  C  Y N 326 
TRP NE1  N  Y N 327 
TRP CE2  C  Y N 328 
TRP CE3  C  Y N 329 
TRP CZ2  C  Y N 330 
TRP CZ3  C  Y N 331 
TRP CH2  C  Y N 332 
TRP OXT  O  N N 333 
TRP H    H  N N 334 
TRP H2   H  N N 335 
TRP HA   H  N N 336 
TRP HB2  H  N N 337 
TRP HB3  H  N N 338 
TRP HD1  H  N N 339 
TRP HE1  H  N N 340 
TRP HE3  H  N N 341 
TRP HZ2  H  N N 342 
TRP HZ3  H  N N 343 
TRP HH2  H  N N 344 
TRP HXT  H  N N 345 
TYR N    N  N N 346 
TYR CA   C  N S 347 
TYR C    C  N N 348 
TYR O    O  N N 349 
TYR CB   C  N N 350 
TYR CG   C  Y N 351 
TYR CD1  C  Y N 352 
TYR CD2  C  Y N 353 
TYR CE1  C  Y N 354 
TYR CE2  C  Y N 355 
TYR CZ   C  Y N 356 
TYR OH   O  N N 357 
TYR OXT  O  N N 358 
TYR H    H  N N 359 
TYR H2   H  N N 360 
TYR HA   H  N N 361 
TYR HB2  H  N N 362 
TYR HB3  H  N N 363 
TYR HD1  H  N N 364 
TYR HD2  H  N N 365 
TYR HE1  H  N N 366 
TYR HE2  H  N N 367 
TYR HH   H  N N 368 
TYR HXT  H  N N 369 
VAL N    N  N N 370 
VAL CA   C  N S 371 
VAL C    C  N N 372 
VAL O    O  N N 373 
VAL CB   C  N N 374 
VAL CG1  C  N N 375 
VAL CG2  C  N N 376 
VAL OXT  O  N N 377 
VAL H    H  N N 378 
VAL H2   H  N N 379 
VAL HA   H  N N 380 
VAL HB   H  N N 381 
VAL HG11 H  N N 382 
VAL HG12 H  N N 383 
VAL HG13 H  N N 384 
VAL HG21 H  N N 385 
VAL HG22 H  N N 386 
VAL HG23 H  N N 387 
VAL HXT  H  N N 388 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_pdbx_audit_support.funding_organization   
'NextGenerationEU-MUR PNRR Extended Partnership initiative on Emerging Infectious Diseases (INF-ACT)' 
_pdbx_audit_support.country                Italy 
_pdbx_audit_support.grant_number           2022JMFC3X 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   4s1y 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9HNB 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.017221 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.003833 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011554 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.017218 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C  6  6  2.310  20.844 1.020  10.208 1.589  0.569  0.865 51.651 0.216   
H  1  1  0.493  10.511 0.323  26.126 0.140  3.142  0.041 57.800 0.003   
N  7  7  12.222 0.006  3.135  9.893  2.014  28.997 1.167 0.583  -11.538 
O  8  8  3.049  13.277 2.287  5.701  1.546  0.324  0.867 32.909 0.251   
PT 78 78 27.022 1.513  17.774 8.812  15.722 0.425  5.787 38.610 3.217   
S  16 16 6.905  1.468  5.203  22.215 1.438  0.254  1.586 56.172 1.056   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N  N   . SER A 1 5   ? -15.508 -19.542 47.258  1.000 153.634 ? 5   SER AAA N   1 ? 
ATOM   2    C  CA  . SER A 1 5   ? -14.304 -18.924 47.926  1.000 156.066 ? 5   SER AAA CA  1 ? 
ATOM   3    C  C   . SER A 1 5   ? -14.720 -17.810 48.881  1.000 153.310 ? 5   SER AAA C   1 ? 
ATOM   4    O  O   . SER A 1 5   ? -15.828 -17.257 48.753  1.000 149.377 ? 5   SER AAA O   1 ? 
ATOM   5    C  CB  . SER A 1 5   ? -13.318 -18.414 46.903  1.000 159.739 ? 5   SER AAA CB  1 ? 
ATOM   6    O  OG  . SER A 1 5   ? -12.233 -17.742 47.530  1.000 160.197 ? 5   SER AAA OG  1 ? 
ATOM   7    N  N   . GLU A 1 6   ? -13.801 -17.434 49.770  1.000 153.917 ? 6   GLU AAA N   1 ? 
ATOM   8    C  CA  . GLU A 1 6   ? -14.090 -16.492 50.874  1.000 161.759 ? 6   GLU AAA CA  1 ? 
ATOM   9    C  C   . GLU A 1 6   ? -13.339 -15.177 50.678  1.000 160.864 ? 6   GLU AAA C   1 ? 
ATOM   10   O  O   . GLU A 1 6   ? -13.980 -14.120 50.708  1.000 166.548 ? 6   GLU AAA O   1 ? 
ATOM   11   C  CB  . GLU A 1 6   ? -13.763 -17.159 52.214  1.000 167.219 ? 6   GLU AAA CB  1 ? 
ATOM   12   C  CG  . GLU A 1 6   ? -14.211 -16.359 53.431  1.000 167.618 ? 6   GLU AAA CG  1 ? 
ATOM   13   C  CD  . GLU A 1 6   ? -15.714 -16.198 53.607  1.000 159.172 ? 6   GLU AAA CD  1 ? 
ATOM   14   O  OE1 . GLU A 1 6   ? -16.467 -17.084 53.151  1.000 147.453 ? 6   GLU AAA OE1 1 ? 
ATOM   15   O  OE2 . GLU A 1 6   ? -16.126 -15.184 54.209  1.000 152.918 ? 6   GLU AAA OE2 1 ? 
ATOM   16   N  N   . VAL A 1 7   ? -12.014 -15.235 50.546  1.000 153.921 ? 7   VAL AAA N   1 ? 
ATOM   17   C  CA  . VAL A 1 7   ? -11.168 -14.041 50.243  1.000 150.447 ? 7   VAL AAA CA  1 ? 
ATOM   18   C  C   . VAL A 1 7   ? -11.927 -13.013 49.390  1.000 154.926 ? 7   VAL AAA C   1 ? 
ATOM   19   O  O   . VAL A 1 7   ? -12.020 -11.802 49.752  1.000 166.501 ? 7   VAL AAA O   1 ? 
ATOM   20   C  CB  . VAL A 1 7   ? -9.868  -14.449 49.517  1.000 144.204 ? 7   VAL AAA CB  1 ? 
ATOM   21   C  CG1 . VAL A 1 7   ? -8.858  -13.312 49.496  1.000 143.956 ? 7   VAL AAA CG1 1 ? 
ATOM   22   C  CG2 . VAL A 1 7   ? -9.236  -15.703 50.100  1.000 144.151 ? 7   VAL AAA CG2 1 ? 
ATOM   23   N  N   . ALA A 1 8   ? -12.419 -13.493 48.252  1.000 148.564 ? 8   ALA AAA N   1 ? 
ATOM   24   C  CA  . ALA A 1 8   ? -13.151 -12.693 47.259  1.000 141.851 ? 8   ALA AAA CA  1 ? 
ATOM   25   C  C   . ALA A 1 8   ? -14.344 -11.986 47.887  1.000 140.543 ? 8   ALA AAA C   1 ? 
ATOM   26   O  O   . ALA A 1 8   ? -14.403 -10.753 47.840  1.000 140.054 ? 8   ALA AAA O   1 ? 
ATOM   27   C  CB  . ALA A 1 8   ? -13.585 -13.573 46.114  1.000 138.797 ? 8   ALA AAA CB  1 ? 
ATOM   28   N  N   . HIS A 1 9   ? -15.262 -12.758 48.464  1.000 139.306 ? 9   HIS AAA N   1 ? 
ATOM   29   C  CA  . HIS A 1 9   ? -16.471 -12.218 49.138  1.000 143.881 ? 9   HIS AAA CA  1 ? 
ATOM   30   C  C   . HIS A 1 9   ? -16.124 -11.007 50.017  1.000 145.110 ? 9   HIS AAA C   1 ? 
ATOM   31   O  O   . HIS A 1 9   ? -16.937 -10.048 50.114  1.000 148.666 ? 9   HIS AAA O   1 ? 
ATOM   32   C  CB  . HIS A 1 9   ? -17.184 -13.329 49.920  1.000 148.713 ? 9   HIS AAA CB  1 ? 
ATOM   33   C  CG  . HIS A 1 9   ? -18.360 -12.855 50.707  1.000 157.052 ? 9   HIS AAA CG  1 ? 
ATOM   34   N  ND1 . HIS A 1 9   ? -19.336 -12.036 50.166  1.000 154.510 ? 9   HIS AAA ND1 1 ? 
ATOM   35   C  CD2 . HIS A 1 9   ? -18.726 -13.088 51.985  1.000 167.875 ? 9   HIS AAA CD2 1 ? 
ATOM   36   C  CE1 . HIS A 1 9   ? -20.247 -11.779 51.084  1.000 159.328 ? 9   HIS AAA CE1 1 ? 
ATOM   37   N  NE2 . HIS A 1 9   ? -19.898 -12.415 52.207  1.000 169.650 ? 9   HIS AAA NE2 1 ? 
ATOM   38   N  N   . ARG A 1 10  ? -14.942 -11.021 50.628  1.000 143.355 ? 10  ARG AAA N   1 ? 
ATOM   39   C  CA  . ARG A 1 10  ? -14.493 -9.914  51.494  1.000 135.760 ? 10  ARG AAA CA  1 ? 
ATOM   40   C  C   . ARG A 1 10  ? -13.890 -8.807  50.648  1.000 129.751 ? 10  ARG AAA C   1 ? 
ATOM   41   O  O   . ARG A 1 10  ? -14.424 -7.697  50.619  1.000 123.291 ? 10  ARG AAA O   1 ? 
ATOM   42   C  CB  . ARG A 1 10  ? -13.528 -10.436 52.568  1.000 134.394 ? 10  ARG AAA CB  1 ? 
ATOM   43   C  CG  . ARG A 1 10  ? -14.100 -11.537 53.455  1.000 128.783 ? 10  ARG AAA CG  1 ? 
ATOM   44   C  CD  . ARG A 1 10  ? -15.350 -11.122 54.211  1.000 129.551 ? 10  ARG AAA CD  1 ? 
ATOM   45   N  NE  . ARG A 1 10  ? -16.000 -12.232 54.896  1.000 131.272 ? 10  ARG AAA NE  1 ? 
ATOM   46   C  CZ  . ARG A 1 10  ? -17.165 -12.153 55.542  1.000 138.245 ? 10  ARG AAA CZ  1 ? 
ATOM   47   N  NH1 . ARG A 1 10  ? -17.826 -11.007 55.605  1.000 140.072 ? 10  ARG AAA NH1 1 ? 
ATOM   48   N  NH2 . ARG A 1 10  ? -17.669 -13.225 56.129  1.000 140.708 ? 10  ARG AAA NH2 1 ? 
ATOM   49   N  N   . PHE A 1 11  ? -12.804 -9.117  49.952  1.000 128.663 ? 11  PHE AAA N   1 ? 
ATOM   50   C  CA  . PHE A 1 11  ? -12.213 -8.144  49.006  1.000 132.806 ? 11  PHE AAA CA  1 ? 
ATOM   51   C  C   . PHE A 1 11  ? -13.319 -7.295  48.358  1.000 133.938 ? 11  PHE AAA C   1 ? 
ATOM   52   O  O   . PHE A 1 11  ? -13.239 -6.052  48.363  1.000 135.061 ? 11  PHE AAA O   1 ? 
ATOM   53   C  CB  . PHE A 1 11  ? -11.357 -8.854  47.954  1.000 133.301 ? 11  PHE AAA CB  1 ? 
ATOM   54   C  CG  . PHE A 1 11  ? -10.379 -7.953  47.242  1.000 138.237 ? 11  PHE AAA CG  1 ? 
ATOM   55   C  CD1 . PHE A 1 11  ? -10.805 -7.088  46.246  1.000 142.670 ? 11  PHE AAA CD1 1 ? 
ATOM   56   C  CD2 . PHE A 1 11  ? -9.032  -7.961  47.573  1.000 140.787 ? 11  PHE AAA CD2 1 ? 
ATOM   57   C  CE1 . PHE A 1 11  ? -9.908  -6.252  45.597  1.000 144.539 ? 11  PHE AAA CE1 1 ? 
ATOM   58   C  CE2 . PHE A 1 11  ? -8.136  -7.125  46.922  1.000 142.415 ? 11  PHE AAA CE2 1 ? 
ATOM   59   C  CZ  . PHE A 1 11  ? -8.575  -6.272  45.935  1.000 141.820 ? 11  PHE AAA CZ  1 ? 
ATOM   60   N  N   . LYS A 1 12  ? -14.350 -7.950  47.829  1.000 132.404 ? 12  LYS AAA N   1 ? 
ATOM   61   C  CA  . LYS A 1 12  ? -15.488 -7.263  47.160  1.000 135.611 ? 12  LYS AAA CA  1 ? 
ATOM   62   C  C   . LYS A 1 12  ? -16.225 -6.321  48.104  1.000 132.765 ? 12  LYS AAA C   1 ? 
ATOM   63   O  O   . LYS A 1 12  ? -16.372 -5.117  47.797  1.000 128.857 ? 12  LYS AAA O   1 ? 
ATOM   64   C  CB  . LYS A 1 12  ? -16.470 -8.295  46.600  1.000 143.604 ? 12  LYS AAA CB  1 ? 
ATOM   65   C  CG  . LYS A 1 12  ? -15.942 -9.110  45.428  1.000 154.148 ? 12  LYS AAA CG  1 ? 
ATOM   66   C  CD  . LYS A 1 12  ? -16.900 -10.179 44.951  1.000 161.889 ? 12  LYS AAA CD  1 ? 
ATOM   67   C  CE  . LYS A 1 12  ? -16.372 -10.958 43.765  1.000 163.705 ? 12  LYS AAA CE  1 ? 
ATOM   68   N  NZ  . LYS A 1 12  ? -17.311 -12.028 43.355  1.000 166.645 ? 12  LYS AAA NZ  1 ? 
ATOM   69   N  N   . ASP A 1 13  ? -16.694 -6.854  49.220  1.000 136.601 ? 13  ASP AAA N   1 ? 
ATOM   70   C  CA  . ASP A 1 13  ? -17.584 -6.095  50.122  1.000 141.941 ? 13  ASP AAA CA  1 ? 
ATOM   71   C  C   . ASP A 1 13  ? -16.808 -4.931  50.717  1.000 139.655 ? 13  ASP AAA C   1 ? 
ATOM   72   O  O   . ASP A 1 13  ? -17.345 -3.823  50.758  1.000 145.654 ? 13  ASP AAA O   1 ? 
ATOM   73   C  CB  . ASP A 1 13  ? -18.217 -6.983  51.200  1.000 145.313 ? 13  ASP AAA CB  1 ? 
ATOM   74   C  CG  . ASP A 1 13  ? -19.546 -7.600  50.790  1.000 142.855 ? 13  ASP AAA CG  1 ? 
ATOM   75   O  OD1 . ASP A 1 13  ? -19.638 -8.091  49.646  1.000 144.635 ? 13  ASP AAA OD1 1 ? 
ATOM   76   O  OD2 . ASP A 1 13  ? -20.488 -7.570  51.613  1.000 133.728 ? 13  ASP AAA OD2 1 ? 
ATOM   77   N  N   . LEU A 1 14  ? -15.558 -5.180  51.084  1.000 132.495 ? 14  LEU AAA N   1 ? 
ATOM   78   C  CA  . LEU A 1 14  ? -14.702 -4.194  51.777  1.000 126.836 ? 14  LEU AAA CA  1 ? 
ATOM   79   C  C   . LEU A 1 14  ? -13.967 -3.227  50.853  1.000 121.776 ? 14  LEU AAA C   1 ? 
ATOM   80   O  O   . LEU A 1 14  ? -13.545 -2.159  51.325  1.000 123.754 ? 14  LEU AAA O   1 ? 
ATOM   81   C  CB  . LEU A 1 14  ? -13.701 -4.967  52.641  1.000 124.351 ? 14  LEU AAA CB  1 ? 
ATOM   82   C  CG  . LEU A 1 14  ? -14.317 -5.819  53.750  1.000 122.869 ? 14  LEU AAA CG  1 ? 
ATOM   83   C  CD1 . LEU A 1 14  ? -13.261 -6.699  54.395  1.000 125.304 ? 14  LEU AAA CD1 1 ? 
ATOM   84   C  CD2 . LEU A 1 14  ? -14.997 -4.950  54.800  1.000 123.873 ? 14  LEU AAA CD2 1 ? 
ATOM   85   N  N   . GLY A 1 15  ? -13.753 -3.595  49.605  1.000 113.228 ? 15  GLY AAA N   1 ? 
ATOM   86   C  CA  . GLY A 1 15  ? -12.890 -2.780  48.754  1.000 111.814 ? 15  GLY AAA CA  1 ? 
ATOM   87   C  C   . GLY A 1 15  ? -11.418 -2.938  49.057  1.000 112.297 ? 15  GLY AAA C   1 ? 
ATOM   88   O  O   . GLY A 1 15  ? -11.006 -3.148  50.215  1.000 113.076 ? 15  GLY AAA O   1 ? 
ATOM   89   N  N   . GLU A 1 16  ? -10.626 -2.817  48.005  1.000 115.049 ? 16  GLU AAA N   1 ? 
ATOM   90   C  CA  . GLU A 1 16  ? -9.182  -3.071  48.049  1.000 118.974 ? 16  GLU AAA CA  1 ? 
ATOM   91   C  C   . GLU A 1 16  ? -8.597  -2.213  49.157  1.000 124.154 ? 16  GLU AAA C   1 ? 
ATOM   92   O  O   . GLU A 1 16  ? -7.909  -2.736  50.028  1.000 121.885 ? 16  GLU AAA O   1 ? 
ATOM   93   C  CB  . GLU A 1 16  ? -8.593  -2.775  46.668  1.000 123.117 ? 16  GLU AAA CB  1 ? 
ATOM   94   C  CG  . GLU A 1 16  ? -7.080  -2.875  46.572  1.000 127.716 ? 16  GLU AAA CG  1 ? 
ATOM   95   C  CD  . GLU A 1 16  ? -6.508  -2.194  45.336  1.000 126.986 ? 16  GLU AAA CD  1 ? 
ATOM   96   O  OE1 . GLU A 1 16  ? -7.238  -2.088  44.325  1.000 120.643 ? 16  GLU AAA OE1 1 ? 
ATOM   97   O  OE2 . GLU A 1 16  ? -5.342  -1.748  45.389  1.000 124.438 ? 16  GLU AAA OE2 1 ? 
ATOM   98   N  N   . GLU A 1 17  ? -8.899  -0.926  49.134  1.000 127.872 ? 17  GLU AAA N   1 ? 
ATOM   99   C  CA  . GLU A 1 17  ? -8.259  0.017   50.071  1.000 127.918 ? 17  GLU AAA CA  1 ? 
ATOM   100  C  C   . GLU A 1 17  ? -8.340  -0.517  51.495  1.000 120.902 ? 17  GLU AAA C   1 ? 
ATOM   101  O  O   . GLU A 1 17  ? -7.300  -0.766  52.139  1.000 119.443 ? 17  GLU AAA O   1 ? 
ATOM   102  C  CB  . GLU A 1 17  ? -8.909  1.397   49.955  1.000 134.476 ? 17  GLU AAA CB  1 ? 
ATOM   103  C  CG  . GLU A 1 17  ? -8.163  2.483   50.708  1.000 140.604 ? 17  GLU AAA CG  1 ? 
ATOM   104  C  CD  . GLU A 1 17  ? -8.786  3.863   50.588  1.000 146.521 ? 17  GLU AAA CD  1 ? 
ATOM   105  O  OE1 . GLU A 1 17  ? -9.802  3.991   49.869  1.000 146.251 ? 17  GLU AAA OE1 1 ? 
ATOM   106  O  OE2 . GLU A 1 17  ? -8.253  4.808   51.208  1.000 153.634 ? 17  GLU AAA OE2 1 ? 
ATOM   107  N  N   . ASN A 1 18  ? -9.561  -0.707  51.955  1.000 109.405 ? 18  ASN AAA N   1 ? 
ATOM   108  C  CA  . ASN A 1 18  ? -9.811  -1.162  53.326  1.000 99.254  ? 18  ASN AAA CA  1 ? 
ATOM   109  C  C   . ASN A 1 18  ? -9.279  -2.577  53.530  1.000 99.410  ? 18  ASN AAA C   1 ? 
ATOM   110  O  O   . ASN A 1 18  ? -8.543  -2.796  54.512  1.000 93.941  ? 18  ASN AAA O   1 ? 
ATOM   111  C  CB  . ASN A 1 18  ? -11.293 -1.029  53.671  1.000 91.312  ? 18  ASN AAA CB  1 ? 
ATOM   112  C  CG  . ASN A 1 18  ? -11.759 0.408   53.604  1.000 86.937  ? 18  ASN AAA CG  1 ? 
ATOM   113  O  OD1 . ASN A 1 18  ? -11.001 1.323   53.913  1.000 81.875  ? 18  ASN AAA OD1 1 ? 
ATOM   114  N  ND2 . ASN A 1 18  ? -12.998 0.617   53.194  1.000 88.471  ? 18  ASN AAA ND2 1 ? 
ATOM   115  N  N   . PHE A 1 19  ? -9.614  -3.504  52.627  1.000 101.924 ? 19  PHE AAA N   1 ? 
ATOM   116  C  CA  . PHE A 1 19  ? -9.046  -4.879  52.668  1.000 101.621 ? 19  PHE AAA CA  1 ? 
ATOM   117  C  C   . PHE A 1 19  ? -7.577  -4.789  53.060  1.000 94.697  ? 19  PHE AAA C   1 ? 
ATOM   118  O  O   . PHE A 1 19  ? -7.129  -5.370  54.046  1.000 92.502  ? 19  PHE AAA O   1 ? 
ATOM   119  C  CB  . PHE A 1 19  ? -9.215  -5.577  51.315  1.000 105.460 ? 19  PHE AAA CB  1 ? 
ATOM   120  C  CG  . PHE A 1 19  ? -8.594  -6.949  51.227  1.000 106.117 ? 19  PHE AAA CG  1 ? 
ATOM   121  C  CD1 . PHE A 1 19  ? -7.232  -7.098  51.005  1.000 107.268 ? 19  PHE AAA CD1 1 ? 
ATOM   122  C  CD2 . PHE A 1 19  ? -9.370  -8.092  51.356  1.000 101.577 ? 19  PHE AAA CD2 1 ? 
ATOM   123  C  CE1 . PHE A 1 19  ? -6.662  -8.358  50.919  1.000 106.440 ? 19  PHE AAA CE1 1 ? 
ATOM   124  C  CE2 . PHE A 1 19  ? -8.798  -9.351  51.269  1.000 101.000 ? 19  PHE AAA CE2 1 ? 
ATOM   125  C  CZ  . PHE A 1 19  ? -7.445  -9.482  51.053  1.000 103.691 ? 19  PHE AAA CZ  1 ? 
ATOM   126  N  N   . LYS A 1 20  ? -6.845  -4.028  52.272  1.000 91.471  ? 20  LYS AAA N   1 ? 
ATOM   127  C  CA  . LYS A 1 20  ? -5.392  -3.903  52.407  1.000 98.163  ? 20  LYS AAA CA  1 ? 
ATOM   128  C  C   . LYS A 1 20  ? -4.981  -3.466  53.803  1.000 91.006  ? 20  LYS AAA C   1 ? 
ATOM   129  O  O   . LYS A 1 20  ? -3.949  -3.910  54.319  1.000 92.062  ? 20  LYS AAA O   1 ? 
ATOM   130  C  CB  . LYS A 1 20  ? -4.875  -2.906  51.364  1.000 111.044 ? 20  LYS AAA CB  1 ? 
ATOM   131  C  CG  . LYS A 1 20  ? -4.838  -3.422  49.930  1.000 115.874 ? 20  LYS AAA CG  1 ? 
ATOM   132  C  CD  . LYS A 1 20  ? -3.722  -2.818  49.101  1.000 118.070 ? 20  LYS AAA CD  1 ? 
ATOM   133  C  CE  . LYS A 1 20  ? -2.354  -3.350  49.480  1.000 120.035 ? 20  LYS AAA CE  1 ? 
ATOM   134  N  NZ  . LYS A 1 20  ? -1.269  -2.458  49.014  1.000 123.009 ? 20  LYS AAA NZ  1 ? 
ATOM   135  N  N   . ALA A 1 21  ? -5.759  -2.569  54.379  1.000 83.523  ? 21  ALA AAA N   1 ? 
ATOM   136  C  CA  . ALA A 1 21  ? -5.451  -2.014  55.697  1.000 80.348  ? 21  ALA AAA CA  1 ? 
ATOM   137  C  C   . ALA A 1 21  ? -5.736  -3.074  56.731  1.000 76.814  ? 21  ALA AAA C   1 ? 
ATOM   138  O  O   . ALA A 1 21  ? -4.865  -3.461  57.525  1.000 80.098  ? 21  ALA AAA O   1 ? 
ATOM   139  C  CB  . ALA A 1 21  ? -6.269  -0.771  55.950  1.000 79.579  ? 21  ALA AAA CB  1 ? 
ATOM   140  N  N   . LEU A 1 22  ? -6.961  -3.545  56.702  1.000 71.503  ? 22  LEU AAA N   1 ? 
ATOM   141  C  CA  . LEU A 1 22  ? -7.342  -4.575  57.659  1.000 70.009  ? 22  LEU AAA CA  1 ? 
ATOM   142  C  C   . LEU A 1 22  ? -6.243  -5.622  57.647  1.000 72.506  ? 22  LEU AAA C   1 ? 
ATOM   143  O  O   . LEU A 1 22  ? -5.615  -5.888  58.670  1.000 72.237  ? 22  LEU AAA O   1 ? 
ATOM   144  C  CB  . LEU A 1 22  ? -8.726  -5.114  57.291  1.000 66.340  ? 22  LEU AAA CB  1 ? 
ATOM   145  C  CG  . LEU A 1 22  ? -9.860  -4.099  57.452  1.000 64.128  ? 22  LEU AAA CG  1 ? 
ATOM   146  C  CD1 . LEU A 1 22  ? -11.137 -4.593  56.800  1.000 63.396  ? 22  LEU AAA CD1 1 ? 
ATOM   147  C  CD2 . LEU A 1 22  ? -10.108 -3.782  58.917  1.000 64.542  ? 22  LEU AAA CD2 1 ? 
ATOM   148  N  N   . VAL A 1 23  ? -5.974  -6.154  56.474  1.000 76.977  ? 23  VAL AAA N   1 ? 
ATOM   149  C  CA  . VAL A 1 23  ? -5.085  -7.317  56.368  1.000 81.375  ? 23  VAL AAA CA  1 ? 
ATOM   150  C  C   . VAL A 1 23  ? -3.780  -6.970  57.046  1.000 84.107  ? 23  VAL AAA C   1 ? 
ATOM   151  O  O   . VAL A 1 23  ? -3.174  -7.831  57.676  1.000 84.976  ? 23  VAL AAA O   1 ? 
ATOM   152  C  CB  . VAL A 1 23  ? -4.858  -7.706  54.891  1.000 81.654  ? 23  VAL AAA CB  1 ? 
ATOM   153  C  CG1 . VAL A 1 23  ? -3.692  -8.670  54.721  1.000 81.813  ? 23  VAL AAA CG1 1 ? 
ATOM   154  C  CG2 . VAL A 1 23  ? -6.114  -8.291  54.265  1.000 82.702  ? 23  VAL AAA CG2 1 ? 
ATOM   155  N  N   . LEU A 1 24  ? -3.363  -5.728  56.886  1.000 88.447  ? 24  LEU AAA N   1 ? 
ATOM   156  C  CA  . LEU A 1 24  ? -2.141  -5.255  57.551  1.000 93.053  ? 24  LEU AAA CA  1 ? 
ATOM   157  C  C   . LEU A 1 24  ? -2.336  -5.394  59.050  1.000 93.380  ? 24  LEU AAA C   1 ? 
ATOM   158  O  O   . LEU A 1 24  ? -1.575  -6.114  59.736  1.000 98.378  ? 24  LEU AAA O   1 ? 
ATOM   159  C  CB  . LEU A 1 24  ? -1.874  -3.798  57.147  1.000 94.494  ? 24  LEU AAA CB  1 ? 
ATOM   160  C  CG  . LEU A 1 24  ? -0.642  -3.131  57.763  1.000 94.530  ? 24  LEU AAA CG  1 ? 
ATOM   161  C  CD1 . LEU A 1 24  ? 0.601   -4.002  57.620  1.000 97.785  ? 24  LEU AAA CD1 1 ? 
ATOM   162  C  CD2 . LEU A 1 24  ? -0.404  -1.768  57.134  1.000 92.973  ? 24  LEU AAA CD2 1 ? 
ATOM   163  N  N   . ILE A 1 25  ? -3.386  -4.750  59.529  1.000 89.636  ? 25  ILE AAA N   1 ? 
ATOM   164  C  CA  . ILE A 1 25  ? -3.671  -4.751  60.979  1.000 88.014  ? 25  ILE AAA CA  1 ? 
ATOM   165  C  C   . ILE A 1 25  ? -3.582  -6.193  61.483  1.000 91.960  ? 25  ILE AAA C   1 ? 
ATOM   166  O  O   . ILE A 1 25  ? -2.722  -6.529  62.313  1.000 87.534  ? 25  ILE AAA O   1 ? 
ATOM   167  C  CB  . ILE A 1 25  ? -5.035  -4.095  61.279  1.000 86.081  ? 25  ILE AAA CB  1 ? 
ATOM   168  C  CG1 . ILE A 1 25  ? -5.042  -2.614  60.901  1.000 86.258  ? 25  ILE AAA CG1 1 ? 
ATOM   169  C  CG2 . ILE A 1 25  ? -5.432  -4.284  62.734  1.000 88.556  ? 25  ILE AAA CG2 1 ? 
ATOM   170  C  CD1 . ILE A 1 25  ? -6.423  -2.062  60.650  1.000 88.933  ? 25  ILE AAA CD1 1 ? 
ATOM   171  N  N   . ALA A 1 26  ? -4.441  -7.033  60.932  1.000 99.556  ? 26  ALA AAA N   1 ? 
ATOM   172  C  CA  . ALA A 1 26  ? -4.515  -8.449  61.296  1.000 105.795 ? 26  ALA AAA CA  1 ? 
ATOM   173  C  C   . ALA A 1 26  ? -3.118  -8.951  61.586  1.000 106.912 ? 26  ALA AAA C   1 ? 
ATOM   174  O  O   . ALA A 1 26  ? -2.887  -9.536  62.642  1.000 115.718 ? 26  ALA AAA O   1 ? 
ATOM   175  C  CB  . ALA A 1 26  ? -5.165  -9.240  60.184  1.000 108.166 ? 26  ALA AAA CB  1 ? 
ATOM   176  N  N   . PHE A 1 27  ? -2.215  -8.683  60.654  1.000 104.088 ? 27  PHE AAA N   1 ? 
ATOM   177  C  CA  . PHE A 1 27  ? -0.834  -9.197  60.731  1.000 103.903 ? 27  PHE AAA CA  1 ? 
ATOM   178  C  C   . PHE A 1 27  ? -0.051  -8.537  61.859  1.000 99.783  ? 27  PHE AAA C   1 ? 
ATOM   179  O  O   . PHE A 1 27  ? 0.523   -9.230  62.718  1.000 98.792  ? 27  PHE AAA O   1 ? 
ATOM   180  C  CB  . PHE A 1 27  ? -0.106  -9.020  59.394  1.000 105.115 ? 27  PHE AAA CB  1 ? 
ATOM   181  C  CG  . PHE A 1 27  ? -0.520  -9.981  58.308  1.000 109.495 ? 27  PHE AAA CG  1 ? 
ATOM   182  C  CD1 . PHE A 1 27  ? -1.372  -11.047 58.569  1.000 114.103 ? 27  PHE AAA CD1 1 ? 
ATOM   183  C  CD2 . PHE A 1 27  ? -0.018  -9.840  57.024  1.000 112.676 ? 27  PHE AAA CD2 1 ? 
ATOM   184  C  CE1 . PHE A 1 27  ? -1.733  -11.931 57.564  1.000 118.041 ? 27  PHE AAA CE1 1 ? 
ATOM   185  C  CE2 . PHE A 1 27  ? -0.378  -10.728 56.021  1.000 118.341 ? 27  PHE AAA CE2 1 ? 
ATOM   186  C  CZ  . PHE A 1 27  ? -1.234  -11.771 56.292  1.000 120.175 ? 27  PHE AAA CZ  1 ? 
ATOM   187  N  N   . ALA A 1 28  ? -0.042  -7.210  61.869  1.000 93.502  ? 28  ALA AAA N   1 ? 
ATOM   188  C  CA  . ALA A 1 28  ? 0.786   -6.450  62.824  1.000 89.223  ? 28  ALA AAA CA  1 ? 
ATOM   189  C  C   . ALA A 1 28  ? 0.318   -6.690  64.248  1.000 89.702  ? 28  ALA AAA C   1 ? 
ATOM   190  O  O   . ALA A 1 28  ? 1.106   -6.545  65.179  1.000 92.878  ? 28  ALA AAA O   1 ? 
ATOM   191  C  CB  . ALA A 1 28  ? 0.757   -4.980  62.492  1.000 87.639  ? 28  ALA AAA CB  1 ? 
ATOM   192  N  N   . GLN A 1 29  ? -0.949  -7.026  64.415  1.000 89.803  ? 29  GLN AAA N   1 ? 
ATOM   193  C  CA  . GLN A 1 29  ? -1.456  -7.404  65.731  1.000 90.510  ? 29  GLN AAA CA  1 ? 
ATOM   194  C  C   . GLN A 1 29  ? -0.925  -8.790  66.053  1.000 99.417  ? 29  GLN AAA C   1 ? 
ATOM   195  O  O   . GLN A 1 29  ? -0.503  -9.000  67.192  1.000 100.031 ? 29  GLN AAA O   1 ? 
ATOM   196  C  CB  . GLN A 1 29  ? -2.988  -7.382  65.746  1.000 81.550  ? 29  GLN AAA CB  1 ? 
ATOM   197  C  CG  . GLN A 1 29  ? -3.583  -5.987  65.609  1.000 75.970  ? 29  GLN AAA CG  1 ? 
ATOM   198  C  CD  . GLN A 1 29  ? -5.060  -5.953  65.922  1.000 72.158  ? 29  GLN AAA CD  1 ? 
ATOM   199  O  OE1 . GLN A 1 29  ? -5.759  -6.955  65.788  1.000 69.868  ? 29  GLN AAA OE1 1 ? 
ATOM   200  N  NE2 . GLN A 1 29  ? -5.549  -4.794  66.337  1.000 66.538  ? 29  GLN AAA NE2 1 ? 
ATOM   201  N  N   . TYR A 1 30  ? -0.913  -9.699  65.077  1.000 109.676 ? 30  TYR AAA N   1 ? 
ATOM   202  C  CA  . TYR A 1 30  ? -0.476  -11.095 65.341  1.000 118.624 ? 30  TYR AAA CA  1 ? 
ATOM   203  C  C   . TYR A 1 30  ? 1.017   -11.146 65.657  1.000 119.019 ? 30  TYR AAA C   1 ? 
ATOM   204  O  O   . TYR A 1 30  ? 1.416   -11.670 66.711  1.000 116.047 ? 30  TYR AAA O   1 ? 
ATOM   205  C  CB  . TYR A 1 30  ? -0.855  -12.046 64.197  1.000 130.128 ? 30  TYR AAA CB  1 ? 
ATOM   206  C  CG  . TYR A 1 30  ? -2.239  -12.647 64.293  1.000 141.603 ? 30  TYR AAA CG  1 ? 
ATOM   207  C  CD1 . TYR A 1 30  ? -2.801  -12.969 65.521  1.000 151.632 ? 30  TYR AAA CD1 1 ? 
ATOM   208  C  CD2 . TYR A 1 30  ? -2.986  -12.918 63.156  1.000 143.671 ? 30  TYR AAA CD2 1 ? 
ATOM   209  C  CE1 . TYR A 1 30  ? -4.068  -13.521 65.621  1.000 154.050 ? 30  TYR AAA CE1 1 ? 
ATOM   210  C  CE2 . TYR A 1 30  ? -4.255  -13.471 63.238  1.000 148.281 ? 30  TYR AAA CE2 1 ? 
ATOM   211  C  CZ  . TYR A 1 30  ? -4.798  -13.772 64.475  1.000 154.145 ? 30  TYR AAA CZ  1 ? 
ATOM   212  O  OH  . TYR A 1 30  ? -6.044  -14.318 64.573  1.000 164.150 ? 30  TYR AAA OH  1 ? 
ATOM   213  N  N   . LEU A 1 31  ? 1.841   -10.608 64.771  1.000 127.446 ? 31  LEU AAA N   1 ? 
ATOM   214  C  CA  . LEU A 1 31  ? 3.283   -10.487 65.052  1.000 139.487 ? 31  LEU AAA CA  1 ? 
ATOM   215  C  C   . LEU A 1 31  ? 3.569   -9.015  65.261  1.000 138.772 ? 31  LEU AAA C   1 ? 
ATOM   216  O  O   . LEU A 1 31  ? 3.483   -8.225  64.306  1.000 144.872 ? 31  LEU AAA O   1 ? 
ATOM   217  C  CB  . LEU A 1 31  ? 4.095   -11.066 63.889  1.000 149.134 ? 31  LEU AAA CB  1 ? 
ATOM   218  C  CG  . LEU A 1 31  ? 3.757   -12.503 63.487  1.000 154.816 ? 31  LEU AAA CG  1 ? 
ATOM   219  C  CD1 . LEU A 1 31  ? 4.222   -12.789 62.066  1.000 157.039 ? 31  LEU AAA CD1 1 ? 
ATOM   220  C  CD2 . LEU A 1 31  ? 4.366   -13.506 64.458  1.000 155.550 ? 31  LEU AAA CD2 1 ? 
ATOM   221  N  N   . GLN A 1 32  ? 3.887   -8.646  66.490  1.000 135.191 ? 32  GLN AAA N   1 ? 
ATOM   222  C  CA  . GLN A 1 32  ? 4.052   -7.231  66.875  1.000 137.342 ? 32  GLN AAA CA  1 ? 
ATOM   223  C  C   . GLN A 1 32  ? 5.509   -6.813  66.756  1.000 143.795 ? 32  GLN AAA C   1 ? 
ATOM   224  O  O   . GLN A 1 32  ? 5.791   -5.623  66.504  1.000 128.087 ? 32  GLN AAA O   1 ? 
ATOM   225  C  CB  . GLN A 1 32  ? 3.493   -7.036  68.285  1.000 134.797 ? 32  GLN AAA CB  1 ? 
ATOM   226  C  CG  . GLN A 1 32  ? 2.000   -7.325  68.371  1.000 131.395 ? 32  GLN AAA CG  1 ? 
ATOM   227  C  CD  . GLN A 1 32  ? 1.556   -7.786  69.737  1.000 127.266 ? 32  GLN AAA CD  1 ? 
ATOM   228  O  OE1 . GLN A 1 32  ? 1.708   -8.951  70.101  1.000 123.115 ? 32  GLN AAA OE1 1 ? 
ATOM   229  N  NE2 . GLN A 1 32  ? 0.976   -6.873  70.497  1.000 124.128 ? 32  GLN AAA NE2 1 ? 
ATOM   230  N  N   . GLN A 1 33  ? 6.414   -7.763  66.934  1.000 167.391 ? 33  GLN AAA N   1 ? 
ATOM   231  C  CA  . GLN A 1 33  ? 7.856   -7.485  66.844  1.000 188.264 ? 33  GLN AAA CA  1 ? 
ATOM   232  C  C   . GLN A 1 33  ? 8.297   -7.403  65.386  1.000 203.592 ? 33  GLN AAA C   1 ? 
ATOM   233  O  O   . GLN A 1 33  ? 9.239   -6.635  65.100  1.000 217.090 ? 33  GLN AAA O   1 ? 
ATOM   234  C  CB  . GLN A 1 33  ? 8.674   -8.539  67.597  1.000 191.134 ? 33  GLN AAA CB  1 ? 
ATOM   235  C  CG  . GLN A 1 33  ? 8.912   -8.194  69.062  1.000 189.651 ? 33  GLN AAA CG  1 ? 
ATOM   236  N  N   . CYS A 1 34  ? 7.642   -8.131  64.480  1.000 204.664 ? 34  CYS AAA N   1 ? 
ATOM   237  C  CA  . CYS A 1 34  ? 8.110   -8.191  63.064  1.000 188.941 ? 34  CYS AAA CA  1 ? 
ATOM   238  C  C   . CYS A 1 34  ? 8.055   -6.810  62.366  1.000 192.031 ? 34  CYS AAA C   1 ? 
ATOM   239  O  O   . CYS A 1 34  ? 7.041   -6.094  62.407  1.000 200.330 ? 34  CYS AAA O   1 ? 
ATOM   240  C  CB  . CYS A 1 34  ? 7.421   -9.279  62.240  1.000 171.119 ? 34  CYS AAA CB  1 ? 
ATOM   241  S  SG  . CYS A 1 34  ? 8.548   -10.623 61.764  1.000 128.059 ? 34  CYS AAA SG  1 ? 
ATOM   242  N  N   . PRO A 1 35  ? 9.190   -6.405  61.724  1.000 179.895 ? 35  PRO AAA N   1 ? 
ATOM   243  C  CA  . PRO A 1 35  ? 9.382   -5.108  61.054  1.000 175.208 ? 35  PRO AAA CA  1 ? 
ATOM   244  C  C   . PRO A 1 35  ? 8.333   -4.744  60.012  1.000 172.548 ? 35  PRO AAA C   1 ? 
ATOM   245  O  O   . PRO A 1 35  ? 7.689   -5.614  59.448  1.000 179.177 ? 35  PRO AAA O   1 ? 
ATOM   246  C  CB  . PRO A 1 35  ? 10.721  -5.266  60.317  1.000 174.468 ? 35  PRO AAA CB  1 ? 
ATOM   247  C  CG  . PRO A 1 35  ? 11.484  -6.274  61.139  1.000 172.376 ? 35  PRO AAA CG  1 ? 
ATOM   248  C  CD  . PRO A 1 35  ? 10.430  -7.203  61.698  1.000 173.639 ? 35  PRO AAA CD  1 ? 
ATOM   249  N  N   . PHE A 1 36  ? 8.254   -3.449  59.734  1.000 159.087 ? 36  PHE AAA N   1 ? 
ATOM   250  C  CA  . PHE A 1 36  ? 7.178   -2.867  58.902  1.000 149.250 ? 36  PHE AAA CA  1 ? 
ATOM   251  C  C   . PHE A 1 36  ? 7.215   -3.433  57.493  1.000 141.646 ? 36  PHE AAA C   1 ? 
ATOM   252  O  O   . PHE A 1 36  ? 6.284   -4.146  57.095  1.000 133.341 ? 36  PHE AAA O   1 ? 
ATOM   253  C  CB  . PHE A 1 36  ? 7.247   -1.338  58.895  1.000 152.353 ? 36  PHE AAA CB  1 ? 
ATOM   254  C  CG  . PHE A 1 36  ? 6.255   -0.678  57.968  1.000 158.188 ? 36  PHE AAA CG  1 ? 
ATOM   255  C  CD1 . PHE A 1 36  ? 4.929   -1.088  57.927  1.000 153.412 ? 36  PHE AAA CD1 1 ? 
ATOM   256  C  CD2 . PHE A 1 36  ? 6.648   0.358   57.134  1.000 163.661 ? 36  PHE AAA CD2 1 ? 
ATOM   257  C  CE1 . PHE A 1 36  ? 4.022   -0.478  57.073  1.000 150.337 ? 36  PHE AAA CE1 1 ? 
ATOM   258  C  CE2 . PHE A 1 36  ? 5.739   0.969   56.284  1.000 160.690 ? 36  PHE AAA CE2 1 ? 
ATOM   259  C  CZ  . PHE A 1 36  ? 4.428   0.550   56.254  1.000 153.989 ? 36  PHE AAA CZ  1 ? 
ATOM   260  N  N   . GLU A 1 37  ? 8.254   -3.104  56.742  1.000 142.796 ? 37  GLU AAA N   1 ? 
ATOM   261  C  CA  . GLU A 1 37  ? 8.422   -3.682  55.391  1.000 147.351 ? 37  GLU AAA CA  1 ? 
ATOM   262  C  C   . GLU A 1 37  ? 8.030   -5.164  55.377  1.000 148.612 ? 37  GLU AAA C   1 ? 
ATOM   263  O  O   . GLU A 1 37  ? 7.190   -5.569  54.544  1.000 144.497 ? 37  GLU AAA O   1 ? 
ATOM   264  C  CB  . GLU A 1 37  ? 9.847   -3.501  54.850  1.000 148.193 ? 37  GLU AAA CB  1 ? 
ATOM   265  C  CG  . GLU A 1 37  ? 10.935  -3.377  55.907  1.000 148.924 ? 37  GLU AAA CG  1 ? 
ATOM   266  C  CD  . GLU A 1 37  ? 11.370  -1.951  56.207  1.000 148.645 ? 37  GLU AAA CD  1 ? 
ATOM   267  O  OE1 . GLU A 1 37  ? 11.606  -1.189  55.245  1.000 146.631 ? 37  GLU AAA OE1 1 ? 
ATOM   268  O  OE2 . GLU A 1 37  ? 11.472  -1.604  57.403  1.000 145.041 ? 37  GLU AAA OE2 1 ? 
ATOM   269  N  N   . ASP A 1 38  ? 8.588   -5.951  56.290  1.000 150.939 ? 38  ASP AAA N   1 ? 
ATOM   270  C  CA  . ASP A 1 38  ? 8.305   -7.400  56.384  1.000 153.756 ? 38  ASP AAA CA  1 ? 
ATOM   271  C  C   . ASP A 1 38  ? 6.823   -7.711  56.258  1.000 149.771 ? 38  ASP AAA C   1 ? 
ATOM   272  O  O   . ASP A 1 38  ? 6.469   -8.679  55.581  1.000 150.232 ? 38  ASP AAA O   1 ? 
ATOM   273  C  CB  . ASP A 1 38  ? 8.833   -7.990  57.696  1.000 160.341 ? 38  ASP AAA CB  1 ? 
ATOM   274  C  CG  . ASP A 1 38  ? 10.300  -8.381  57.657  1.000 165.681 ? 38  ASP AAA CG  1 ? 
ATOM   275  O  OD1 . ASP A 1 38  ? 11.007  -8.086  58.639  1.000 171.481 ? 38  ASP AAA OD1 1 ? 
ATOM   276  O  OD2 . ASP A 1 38  ? 10.721  -8.991  56.654  1.000 166.789 ? 38  ASP AAA OD2 1 ? 
ATOM   277  N  N   . HIS A 1 39  ? 5.969   -6.921  56.883  1.000 149.423 ? 39  HIS AAA N   1 ? 
ATOM   278  C  CA  . HIS A 1 39  ? 4.512   -7.139  56.758  1.000 150.579 ? 39  HIS AAA CA  1 ? 
ATOM   279  C  C   . HIS A 1 39  ? 4.000   -6.735  55.389  1.000 137.671 ? 39  HIS AAA C   1 ? 
ATOM   280  O  O   . HIS A 1 39  ? 3.238   -7.484  54.769  1.000 128.553 ? 39  HIS AAA O   1 ? 
ATOM   281  C  CB  . HIS A 1 39  ? 3.769   -6.398  57.877  1.000 158.338 ? 39  HIS AAA CB  1 ? 
ATOM   282  C  CG  . HIS A 1 39  ? 4.031   -6.967  59.230  1.000 162.518 ? 39  HIS AAA CG  1 ? 
ATOM   283  N  ND1 . HIS A 1 39  ? 3.447   -8.141  59.660  1.000 166.212 ? 39  HIS AAA ND1 1 ? 
ATOM   284  C  CD2 . HIS A 1 39  ? 4.816   -6.541  60.241  1.000 163.156 ? 39  HIS AAA CD2 1 ? 
ATOM   285  C  CE1 . HIS A 1 39  ? 3.858   -8.410  60.881  1.000 166.939 ? 39  HIS AAA CE1 1 ? 
ATOM   286  N  NE2 . HIS A 1 39  ? 4.698   -7.442  61.262  1.000 163.841 ? 39  HIS AAA NE2 1 ? 
ATOM   287  N  N   . VAL A 1 40  ? 4.416   -5.574  54.922  1.000 129.768 ? 40  VAL AAA N   1 ? 
ATOM   288  C  CA  . VAL A 1 40  ? 3.810   -4.975  53.710  1.000 127.595 ? 40  VAL AAA CA  1 ? 
ATOM   289  C  C   . VAL A 1 40  ? 3.893   -5.965  52.545  1.000 130.435 ? 40  VAL AAA C   1 ? 
ATOM   290  O  O   . VAL A 1 40  ? 2.942   -6.105  51.760  1.000 133.862 ? 40  VAL AAA O   1 ? 
ATOM   291  C  CB  . VAL A 1 40  ? 4.474   -3.622  53.375  1.000 125.950 ? 40  VAL AAA CB  1 ? 
ATOM   292  C  CG1 . VAL A 1 40  ? 3.906   -3.002  52.109  1.000 127.689 ? 40  VAL AAA CG1 1 ? 
ATOM   293  C  CG2 . VAL A 1 40  ? 4.366   -2.634  54.528  1.000 124.072 ? 40  VAL AAA CG2 1 ? 
ATOM   294  N  N   . LYS A 1 41  ? 5.022   -6.635  52.437  1.000 132.480 ? 41  LYS AAA N   1 ? 
ATOM   295  C  CA  . LYS A 1 41  ? 5.200   -7.700  51.439  1.000 134.924 ? 41  LYS AAA CA  1 ? 
ATOM   296  C  C   . LYS A 1 41  ? 4.028   -8.674  51.541  1.000 132.215 ? 41  LYS AAA C   1 ? 
ATOM   297  O  O   . LYS A 1 41  ? 3.232   -8.823  50.584  1.000 129.096 ? 41  LYS AAA O   1 ? 
ATOM   298  C  CB  . LYS A 1 41  ? 6.549   -8.390  51.669  1.000 138.776 ? 41  LYS AAA CB  1 ? 
ATOM   299  C  CG  . LYS A 1 41  ? 6.900   -9.484  50.672  1.000 142.984 ? 41  LYS AAA CG  1 ? 
ATOM   300  C  CD  . LYS A 1 41  ? 8.374   -9.842  50.657  1.000 148.061 ? 41  LYS AAA CD  1 ? 
ATOM   301  C  CE  . LYS A 1 41  ? 8.771   -10.799 51.761  1.000 150.127 ? 41  LYS AAA CE  1 ? 
ATOM   302  N  NZ  . LYS A 1 41  ? 8.345   -12.187 51.464  1.000 153.998 ? 41  LYS AAA NZ  1 ? 
ATOM   303  N  N   . LEU A 1 42  ? 3.898   -9.268  52.720  1.000 130.995 ? 42  LEU AAA N   1 ? 
ATOM   304  C  CA  . LEU A 1 42  ? 2.877   -10.302 53.020  1.000 133.243 ? 42  LEU AAA CA  1 ? 
ATOM   305  C  C   . LEU A 1 42  ? 1.503   -9.756  52.691  1.000 138.947 ? 42  LEU AAA C   1 ? 
ATOM   306  O  O   . LEU A 1 42  ? 0.664   -10.475 52.128  1.000 135.080 ? 42  LEU AAA O   1 ? 
ATOM   307  C  CB  . LEU A 1 42  ? 2.933   -10.691 54.503  1.000 130.146 ? 42  LEU AAA CB  1 ? 
ATOM   308  C  CG  . LEU A 1 42  ? 4.225   -11.336 55.001  1.000 129.112 ? 42  LEU AAA CG  1 ? 
ATOM   309  C  CD1 . LEU A 1 42  ? 4.217   -11.430 56.519  1.000 128.323 ? 42  LEU AAA CD1 1 ? 
ATOM   310  C  CD2 . LEU A 1 42  ? 4.425   -12.713 54.387  1.000 131.455 ? 42  LEU AAA CD2 1 ? 
ATOM   311  N  N   . VAL A 1 43  ? 1.276   -8.510  53.051  1.000 146.609 ? 43  VAL AAA N   1 ? 
ATOM   312  C  CA  . VAL A 1 43  ? 0.013   -7.857  52.671  1.000 144.854 ? 43  VAL AAA CA  1 ? 
ATOM   313  C  C   . VAL A 1 43  ? -0.130  -7.965  51.160  1.000 134.955 ? 43  VAL AAA C   1 ? 
ATOM   314  O  O   . VAL A 1 43  ? -1.029  -8.677  50.664  1.000 130.450 ? 43  VAL AAA O   1 ? 
ATOM   315  C  CB  . VAL A 1 43  ? -0.048  -6.389  53.146  1.000 148.251 ? 43  VAL AAA CB  1 ? 
ATOM   316  C  CG1 . VAL A 1 43  ? -1.184  -5.615  52.491  1.000 146.906 ? 43  VAL AAA CG1 1 ? 
ATOM   317  C  CG2 . VAL A 1 43  ? -0.151  -6.298  54.660  1.000 152.957 ? 43  VAL AAA CG2 1 ? 
ATOM   318  N  N   . ASN A 1 44  ? 0.782   -7.321  50.445  1.000 123.732 ? 44  ASN AAA N   1 ? 
ATOM   319  C  CA  . ASN A 1 44  ? 0.672   -7.170  48.974  1.000 116.657 ? 44  ASN AAA CA  1 ? 
ATOM   320  C  C   . ASN A 1 44  ? 0.514   -8.514  48.277  1.000 114.019 ? 44  ASN AAA C   1 ? 
ATOM   321  O  O   . ASN A 1 44  ? -0.329  -8.635  47.380  1.000 112.252 ? 44  ASN AAA O   1 ? 
ATOM   322  C  CB  . ASN A 1 44  ? 1.895   -6.481  48.370  1.000 115.245 ? 44  ASN AAA CB  1 ? 
ATOM   323  C  CG  . ASN A 1 44  ? 2.033   -5.043  48.807  1.000 116.178 ? 44  ASN AAA CG  1 ? 
ATOM   324  O  OD1 . ASN A 1 44  ? 1.050   -4.306  48.842  1.000 122.313 ? 44  ASN AAA OD1 1 ? 
ATOM   325  N  ND2 . ASN A 1 44  ? 3.252   -4.638  49.123  1.000 113.929 ? 44  ASN AAA ND2 1 ? 
ATOM   326  N  N   . GLU A 1 45  ? 1.290   -9.509  48.681  1.000 114.608 ? 45  GLU AAA N   1 ? 
ATOM   327  C  CA  . GLU A 1 45  ? 1.055   -10.883 48.188  1.000 117.429 ? 45  GLU AAA CA  1 ? 
ATOM   328  C  C   . GLU A 1 45  ? -0.422  -11.248 48.323  1.000 122.041 ? 45  GLU AAA C   1 ? 
ATOM   329  O  O   . GLU A 1 45  ? -1.125  -11.476 47.310  1.000 122.539 ? 45  GLU AAA O   1 ? 
ATOM   330  C  CB  . GLU A 1 45  ? 1.953   -11.861 48.943  1.000 115.976 ? 45  GLU AAA CB  1 ? 
ATOM   331  C  CG  . GLU A 1 45  ? 3.387   -11.828 48.449  1.000 116.706 ? 45  GLU AAA CG  1 ? 
ATOM   332  C  CD  . GLU A 1 45  ? 4.462   -11.963 49.511  1.000 116.179 ? 45  GLU AAA CD  1 ? 
ATOM   333  O  OE1 . GLU A 1 45  ? 4.124   -12.275 50.669  1.000 116.428 ? 45  GLU AAA OE1 1 ? 
ATOM   334  O  OE2 . GLU A 1 45  ? 5.641   -11.752 49.170  1.000 115.322 ? 45  GLU AAA OE2 1 ? 
ATOM   335  N  N   . VAL A 1 46  ? -0.889  -11.251 49.563  1.000 123.958 ? 46  VAL AAA N   1 ? 
ATOM   336  C  CA  . VAL A 1 46  ? -2.274  -11.654 49.897  1.000 122.586 ? 46  VAL AAA CA  1 ? 
ATOM   337  C  C   . VAL A 1 46  ? -3.223  -10.893 48.997  1.000 120.040 ? 46  VAL AAA C   1 ? 
ATOM   338  O  O   . VAL A 1 46  ? -4.139  -11.476 48.411  1.000 120.987 ? 46  VAL AAA O   1 ? 
ATOM   339  C  CB  . VAL A 1 46  ? -2.588  -11.419 51.389  1.000 125.295 ? 46  VAL AAA CB  1 ? 
ATOM   340  C  CG1 . VAL A 1 46  ? -4.082  -11.460 51.676  1.000 128.440 ? 46  VAL AAA CG1 1 ? 
ATOM   341  C  CG2 . VAL A 1 46  ? -1.852  -12.411 52.274  1.000 126.767 ? 46  VAL AAA CG2 1 ? 
ATOM   342  N  N   . THR A 1 47  ? -2.979  -9.607  48.883  1.000 115.751 ? 47  THR AAA N   1 ? 
ATOM   343  C  CA  . THR A 1 47  ? -3.826  -8.732  48.079  1.000 113.148 ? 47  THR AAA CA  1 ? 
ATOM   344  C  C   . THR A 1 47  ? -3.827  -9.163  46.608  1.000 115.603 ? 47  THR AAA C   1 ? 
ATOM   345  O  O   . THR A 1 47  ? -4.901  -9.238  45.986  1.000 110.715 ? 47  THR AAA O   1 ? 
ATOM   346  C  CB  . THR A 1 47  ? -3.340  -7.277  48.130  1.000 109.709 ? 47  THR AAA CB  1 ? 
ATOM   347  O  OG1 . THR A 1 47  ? -2.768  -7.021  49.413  1.000 106.123 ? 47  THR AAA OG1 1 ? 
ATOM   348  C  CG2 . THR A 1 47  ? -4.448  -6.289  47.836  1.000 110.638 ? 47  THR AAA CG2 1 ? 
ATOM   349  N  N   . GLU A 1 48  ? -2.655  -9.440  46.044  1.000 124.730 ? 48  GLU AAA N   1 ? 
ATOM   350  C  CA  . GLU A 1 48  ? -2.594  -9.889  44.637  1.000 135.300 ? 48  GLU AAA CA  1 ? 
ATOM   351  C  C   . GLU A 1 48  ? -3.386  -11.170 44.544  1.000 135.789 ? 48  GLU AAA C   1 ? 
ATOM   352  O  O   . GLU A 1 48  ? -4.358  -11.220 43.799  1.000 139.219 ? 48  GLU AAA O   1 ? 
ATOM   353  C  CB  . GLU A 1 48  ? -1.143  -10.022 44.174  1.000 148.452 ? 48  GLU AAA CB  1 ? 
ATOM   354  C  CG  . GLU A 1 48  ? -0.446  -8.678  44.028  1.000 155.295 ? 48  GLU AAA CG  1 ? 
ATOM   355  C  CD  . GLU A 1 48  ? -1.380  -7.506  43.758  1.000 158.883 ? 48  GLU AAA CD  1 ? 
ATOM   356  O  OE1 . GLU A 1 48  ? -1.807  -7.343  42.597  1.000 168.899 ? 48  GLU AAA OE1 1 ? 
ATOM   357  O  OE2 . GLU A 1 48  ? -1.707  -6.779  44.720  1.000 153.709 ? 48  GLU AAA OE2 1 ? 
ATOM   358  N  N   . PHE A 1 49  ? -3.008  -12.152 45.339  1.000 134.379 ? 49  PHE AAA N   1 ? 
ATOM   359  C  CA  . PHE A 1 49  ? -3.716  -13.443 45.332  1.000 135.993 ? 49  PHE AAA CA  1 ? 
ATOM   360  C  C   . PHE A 1 49  ? -5.237  -13.271 45.427  1.000 135.089 ? 49  PHE AAA C   1 ? 
ATOM   361  O  O   . PHE A 1 49  ? -5.975  -13.953 44.715  1.000 139.795 ? 49  PHE AAA O   1 ? 
ATOM   362  C  CB  . PHE A 1 49  ? -3.209  -14.353 46.453  1.000 136.545 ? 49  PHE AAA CB  1 ? 
ATOM   363  C  CG  . PHE A 1 49  ? -3.812  -15.733 46.402  1.000 145.220 ? 49  PHE AAA CG  1 ? 
ATOM   364  C  CD1 . PHE A 1 49  ? -4.997  -16.011 47.065  1.000 151.343 ? 49  PHE AAA CD1 1 ? 
ATOM   365  C  CD2 . PHE A 1 49  ? -3.225  -16.739 45.650  1.000 152.345 ? 49  PHE AAA CD2 1 ? 
ATOM   366  C  CE1 . PHE A 1 49  ? -5.566  -17.274 47.002  1.000 156.838 ? 49  PHE AAA CE1 1 ? 
ATOM   367  C  CE2 . PHE A 1 49  ? -3.796  -18.002 45.586  1.000 158.018 ? 49  PHE AAA CE2 1 ? 
ATOM   368  C  CZ  . PHE A 1 49  ? -4.967  -18.265 46.261  1.000 157.750 ? 49  PHE AAA CZ  1 ? 
ATOM   369  N  N   . ALA A 1 50  ? -5.731  -12.406 46.300  1.000 125.632 ? 50  ALA AAA N   1 ? 
ATOM   370  C  CA  . ALA A 1 50  ? -7.188  -12.215 46.409  1.000 117.344 ? 50  ALA AAA CA  1 ? 
ATOM   371  C  C   . ALA A 1 50  ? -7.757  -11.922 45.030  1.000 116.661 ? 50  ALA AAA C   1 ? 
ATOM   372  O  O   . ALA A 1 50  ? -8.760  -12.525 44.606  1.000 122.686 ? 50  ALA AAA O   1 ? 
ATOM   373  C  CB  . ALA A 1 50  ? -7.488  -11.090 47.370  1.000 113.193 ? 50  ALA AAA CB  1 ? 
ATOM   374  N  N   . LYS A 1 51  ? -7.087  -10.994 44.364  1.000 116.490 ? 51  LYS AAA N   1 ? 
ATOM   375  C  CA  . LYS A 1 51  ? -7.541  -10.446 43.081  1.000 120.136 ? 51  LYS AAA CA  1 ? 
ATOM   376  C  C   . LYS A 1 51  ? -7.703  -11.590 42.098  1.000 122.296 ? 51  LYS AAA C   1 ? 
ATOM   377  O  O   . LYS A 1 51  ? -8.739  -11.686 41.430  1.000 122.568 ? 51  LYS AAA O   1 ? 
ATOM   378  C  CB  . LYS A 1 51  ? -6.566  -9.374  42.579  1.000 119.441 ? 51  LYS AAA CB  1 ? 
ATOM   379  C  CG  . LYS A 1 51  ? -6.608  -8.061  43.351  1.000 120.036 ? 51  LYS AAA CG  1 ? 
ATOM   380  C  CD  . LYS A 1 51  ? -5.372  -7.199  43.172  1.000 121.190 ? 51  LYS AAA CD  1 ? 
ATOM   381  C  CE  . LYS A 1 51  ? -5.569  -5.770  43.638  1.000 119.313 ? 51  LYS AAA CE  1 ? 
ATOM   382  N  NZ  . LYS A 1 51  ? -4.337  -4.960  43.481  1.000 115.184 ? 51  LYS AAA NZ  1 ? 
ATOM   383  N  N   . THR A 1 52  ? -6.716  -12.473 42.076  1.000 125.002 ? 52  THR AAA N   1 ? 
ATOM   384  C  CA  . THR A 1 52  ? -6.810  -13.697 41.268  1.000 127.950 ? 52  THR AAA CA  1 ? 
ATOM   385  C  C   . THR A 1 52  ? -8.153  -14.361 41.552  1.000 135.945 ? 52  THR AAA C   1 ? 
ATOM   386  O  O   . THR A 1 52  ? -8.940  -14.541 40.629  1.000 141.477 ? 52  THR AAA O   1 ? 
ATOM   387  C  CB  . THR A 1 52  ? -5.659  -14.690 41.503  1.000 126.730 ? 52  THR AAA CB  1 ? 
ATOM   388  O  OG1 . THR A 1 52  ? -5.850  -15.365 42.746  1.000 125.229 ? 52  THR AAA OG1 1 ? 
ATOM   389  C  CG2 . THR A 1 52  ? -4.286  -14.053 41.482  1.000 128.773 ? 52  THR AAA CG2 1 ? 
ATOM   390  N  N   . CYS A 1 53  ? -8.433  -14.650 42.817  1.000 144.928 ? 53  CYS AAA N   1 ? 
ATOM   391  C  CA  . CYS A 1 53  ? -9.708  -15.287 43.223  1.000 151.929 ? 53  CYS AAA CA  1 ? 
ATOM   392  C  C   . CYS A 1 53  ? -10.929 -14.462 42.843  1.000 151.751 ? 53  CYS AAA C   1 ? 
ATOM   393  O  O   . CYS A 1 53  ? -11.993 -15.047 42.644  1.000 161.579 ? 53  CYS AAA O   1 ? 
ATOM   394  C  CB  . CYS A 1 53  ? -9.778  -15.522 44.729  1.000 158.215 ? 53  CYS AAA CB  1 ? 
ATOM   395  S  SG  . CYS A 1 53  ? -8.348  -16.405 45.402  1.000 173.308 ? 53  CYS AAA SG  1 ? 
ATOM   396  N  N   . VAL A 1 54  ? -10.791 -13.140 42.759  1.000 147.816 ? 54  VAL AAA N   1 ? 
ATOM   397  C  CA  . VAL A 1 54  ? -11.896 -12.282 42.244  1.000 144.986 ? 54  VAL AAA CA  1 ? 
ATOM   398  C  C   . VAL A 1 54  ? -12.155 -12.563 40.771  1.000 139.481 ? 54  VAL AAA C   1 ? 
ATOM   399  O  O   . VAL A 1 54  ? -13.317 -12.481 40.313  1.000 130.783 ? 54  VAL AAA O   1 ? 
ATOM   400  C  CB  . VAL A 1 54  ? -11.628 -10.776 42.446  1.000 150.741 ? 54  VAL AAA CB  1 ? 
ATOM   401  C  CG1 . VAL A 1 54  ? -12.750 -9.922  41.870  1.000 152.668 ? 54  VAL AAA CG1 1 ? 
ATOM   402  C  CG2 . VAL A 1 54  ? -11.401 -10.417 43.906  1.000 155.634 ? 54  VAL AAA CG2 1 ? 
ATOM   403  N  N   . ALA A 1 55  ? -11.088 -12.842 40.041  1.000 144.777 ? 55  ALA AAA N   1 ? 
ATOM   404  C  CA  . ALA A 1 55  ? -11.195 -13.189 38.617  1.000 154.821 ? 55  ALA AAA CA  1 ? 
ATOM   405  C  C   . ALA A 1 55  ? -11.730 -14.618 38.474  1.000 165.756 ? 55  ALA AAA C   1 ? 
ATOM   406  O  O   . ALA A 1 55  ? -12.748 -14.827 37.795  1.000 173.239 ? 55  ALA AAA O   1 ? 
ATOM   407  C  CB  . ALA A 1 55  ? -9.855  -13.015 37.941  1.000 153.265 ? 55  ALA AAA CB  1 ? 
ATOM   408  N  N   . ASP A 1 56  ? -11.055 -15.572 39.116  1.000 169.332 ? 56  ASP AAA N   1 ? 
ATOM   409  C  CA  . ASP A 1 56  ? -11.428 -17.008 39.137  1.000 164.485 ? 56  ASP AAA CA  1 ? 
ATOM   410  C  C   . ASP A 1 56  ? -11.748 -17.439 40.563  1.000 169.764 ? 56  ASP AAA C   1 ? 
ATOM   411  O  O   . ASP A 1 56  ? -10.845 -17.862 41.303  1.000 172.668 ? 56  ASP AAA O   1 ? 
ATOM   412  C  CB  . ASP A 1 56  ? -10.315 -17.875 38.541  1.000 155.135 ? 56  ASP AAA CB  1 ? 
ATOM   413  N  N   . GLU A 1 57  ? -13.018 -17.345 40.936  1.000 173.821 ? 57  GLU AAA N   1 ? 
ATOM   414  C  CA  . GLU A 1 57  ? -13.474 -17.793 42.265  1.000 174.104 ? 57  GLU AAA CA  1 ? 
ATOM   415  C  C   . GLU A 1 57  ? -13.180 -19.283 42.459  1.000 166.108 ? 57  GLU AAA C   1 ? 
ATOM   416  O  O   . GLU A 1 57  ? -13.063 -19.719 43.611  1.000 159.297 ? 57  GLU AAA O   1 ? 
ATOM   417  C  CB  . GLU A 1 57  ? -14.959 -17.475 42.466  1.000 179.390 ? 57  GLU AAA CB  1 ? 
ATOM   418  C  CG  . GLU A 1 57  ? -15.368 -17.412 43.930  1.000 185.180 ? 57  GLU AAA CG  1 ? 
ATOM   419  C  CD  . GLU A 1 57  ? -16.539 -16.495 44.246  1.000 190.794 ? 57  GLU AAA CD  1 ? 
ATOM   420  O  OE1 . GLU A 1 57  ? -16.465 -15.296 43.906  1.000 192.232 ? 57  GLU AAA OE1 1 ? 
ATOM   421  O  OE2 . GLU A 1 57  ? -17.522 -16.982 44.840  1.000 199.260 ? 57  GLU AAA OE2 1 ? 
ATOM   422  N  N   . SER A 1 58  ? -13.028 -20.037 41.374  1.000 161.735 ? 58  SER AAA N   1 ? 
ATOM   423  C  CA  . SER A 1 58  ? -12.521 -21.427 41.421  1.000 162.030 ? 58  SER AAA CA  1 ? 
ATOM   424  C  C   . SER A 1 58  ? -11.077 -21.547 40.911  1.000 156.393 ? 58  SER AAA C   1 ? 
ATOM   425  O  O   . SER A 1 58  ? -10.758 -22.535 40.215  1.000 149.576 ? 58  SER AAA O   1 ? 
ATOM   426  C  CB  . SER A 1 58  ? -13.460 -22.335 40.665  1.000 166.239 ? 58  SER AAA CB  1 ? 
ATOM   427  O  OG  . SER A 1 58  ? -13.819 -21.761 39.416  1.000 168.931 ? 58  SER AAA OG  1 ? 
ATOM   428  N  N   . ALA A 1 59  ? -10.214 -20.589 41.259  1.000 155.331 ? 59  ALA AAA N   1 ? 
ATOM   429  C  CA  . ALA A 1 59  ? -8.748  -20.698 41.051  1.000 151.322 ? 59  ALA AAA CA  1 ? 
ATOM   430  C  C   . ALA A 1 59  ? -8.127  -21.606 42.119  1.000 144.283 ? 59  ALA AAA C   1 ? 
ATOM   431  O  O   . ALA A 1 59  ? -8.841  -22.074 43.015  1.000 137.836 ? 59  ALA AAA O   1 ? 
ATOM   432  C  CB  . ALA A 1 59  ? -8.114  -19.326 41.056  1.000 152.270 ? 59  ALA AAA CB  1 ? 
ATOM   433  N  N   . GLU A 1 60  ? -6.818  -21.834 42.054  1.000 142.585 ? 60  GLU AAA N   1 ? 
ATOM   434  C  CA  . GLU A 1 60  ? -6.117  -22.695 43.032  1.000 147.660 ? 60  GLU AAA CA  1 ? 
ATOM   435  C  C   . GLU A 1 60  ? -6.037  -21.962 44.358  1.000 155.346 ? 60  GLU AAA C   1 ? 
ATOM   436  O  O   . GLU A 1 60  ? -5.799  -20.747 44.356  1.000 154.108 ? 60  GLU AAA O   1 ? 
ATOM   437  C  CB  . GLU A 1 60  ? -4.722  -23.054 42.517  1.000 144.400 ? 60  GLU AAA CB  1 ? 
ATOM   438  N  N   . ASN A 1 61  ? -6.274  -22.696 45.438  1.000 159.386 ? 61  ASN AAA N   1 ? 
ATOM   439  C  CA  . ASN A 1 61  ? -6.106  -22.212 46.831  1.000 157.909 ? 61  ASN AAA CA  1 ? 
ATOM   440  C  C   . ASN A 1 61  ? -7.147  -21.164 47.273  1.000 157.829 ? 61  ASN AAA C   1 ? 
ATOM   441  O  O   . ASN A 1 61  ? -7.134  -20.751 48.453  1.000 159.689 ? 61  ASN AAA O   1 ? 
ATOM   442  C  CB  . ASN A 1 61  ? -4.678  -21.704 47.075  1.000 154.557 ? 61  ASN AAA CB  1 ? 
ATOM   443  C  CG  . ASN A 1 61  ? -3.614  -22.772 46.923  1.000 149.685 ? 61  ASN AAA CG  1 ? 
ATOM   444  O  OD1 . ASN A 1 61  ? -3.879  -23.960 47.102  1.000 145.380 ? 61  ASN AAA OD1 1 ? 
ATOM   445  N  ND2 . ASN A 1 61  ? -2.398  -22.356 46.605  1.000 140.218 ? 61  ASN AAA ND2 1 ? 
ATOM   446  N  N   . CYS A 1 62  ? -8.055  -20.734 46.408  1.000 157.163 ? 62  CYS AAA N   1 ? 
ATOM   447  C  CA  . CYS A 1 62  ? -9.087  -19.746 46.805  1.000 159.122 ? 62  CYS AAA CA  1 ? 
ATOM   448  C  C   . CYS A 1 62  ? -10.173 -20.408 47.650  1.000 161.666 ? 62  CYS AAA C   1 ? 
ATOM   449  O  O   . CYS A 1 62  ? -10.915 -19.701 48.378  1.000 159.876 ? 62  CYS AAA O   1 ? 
ATOM   450  C  CB  . CYS A 1 62  ? -9.705  -19.086 45.581  1.000 162.013 ? 62  CYS AAA CB  1 ? 
ATOM   451  S  SG  . CYS A 1 62  ? -8.475  -18.243 44.556  1.000 174.118 ? 62  CYS AAA SG  1 ? 
ATOM   452  N  N   . ASP A 1 63  ? -10.232 -21.732 47.574  1.000 168.433 ? 63  ASP AAA N   1 ? 
ATOM   453  C  CA  . ASP A 1 63  ? -11.137 -22.556 48.406  1.000 174.146 ? 63  ASP AAA CA  1 ? 
ATOM   454  C  C   . ASP A 1 63  ? -10.804 -22.455 49.903  1.000 179.597 ? 63  ASP AAA C   1 ? 
ATOM   455  O  O   . ASP A 1 63  ? -11.656 -22.869 50.714  1.000 194.090 ? 63  ASP AAA O   1 ? 
ATOM   456  C  CB  . ASP A 1 63  ? -11.099 -24.023 47.970  1.000 173.670 ? 63  ASP AAA CB  1 ? 
ATOM   457  N  N   . LYS A 1 64  ? -9.648  -21.896 50.286  1.000 178.804 ? 64  LYS AAA N   1 ? 
ATOM   458  C  CA  . LYS A 1 64  ? -9.186  -21.890 51.710  1.000 172.762 ? 64  LYS AAA CA  1 ? 
ATOM   459  C  C   . LYS A 1 64  ? -9.881  -20.845 52.589  1.000 170.043 ? 64  LYS AAA C   1 ? 
ATOM   460  O  O   . LYS A 1 64  ? -10.371 -19.801 52.098  1.000 166.452 ? 64  LYS AAA O   1 ? 
ATOM   461  C  CB  . LYS A 1 64  ? -7.679  -21.620 51.789  1.000 171.194 ? 64  LYS AAA CB  1 ? 
ATOM   462  C  CG  . LYS A 1 64  ? -6.786  -22.578 51.009  1.000 170.969 ? 64  LYS AAA CG  1 ? 
ATOM   463  C  CD  . LYS A 1 64  ? -5.857  -23.424 51.859  1.000 164.721 ? 64  LYS AAA CD  1 ? 
ATOM   464  C  CE  . LYS A 1 64  ? -4.668  -23.939 51.073  1.000 160.430 ? 64  LYS AAA CE  1 ? 
ATOM   465  N  NZ  . LYS A 1 64  ? -3.767  -24.771 51.905  1.000 158.126 ? 64  LYS AAA NZ  1 ? 
ATOM   466  N  N   . SER A 1 65  ? -9.828  -21.091 53.895  1.000 164.850 ? 65  SER AAA N   1 ? 
ATOM   467  C  CA  . SER A 1 65  ? -10.321 -20.149 54.918  1.000 159.985 ? 65  SER AAA CA  1 ? 
ATOM   468  C  C   . SER A 1 65  ? -9.249  -19.115 55.236  1.000 156.924 ? 65  SER AAA C   1 ? 
ATOM   469  O  O   . SER A 1 65  ? -8.042  -19.426 55.274  1.000 162.531 ? 65  SER AAA O   1 ? 
ATOM   470  C  CB  . SER A 1 65  ? -10.787 -20.881 56.153  1.000 158.110 ? 65  SER AAA CB  1 ? 
ATOM   471  O  OG  . SER A 1 65  ? -9.698  -21.486 56.835  1.000 157.511 ? 65  SER AAA OG  1 ? 
ATOM   472  N  N   . LEU A 1 66  ? -9.701  -17.904 55.499  1.000 148.040 ? 66  LEU AAA N   1 ? 
ATOM   473  C  CA  . LEU A 1 66  ? -8.806  -16.750 55.660  1.000 145.451 ? 66  LEU AAA CA  1 ? 
ATOM   474  C  C   . LEU A 1 66  ? -7.715  -17.108 56.650  1.000 141.238 ? 66  LEU AAA C   1 ? 
ATOM   475  O  O   . LEU A 1 66  ? -6.535  -16.974 56.340  1.000 136.839 ? 66  LEU AAA O   1 ? 
ATOM   476  C  CB  . LEU A 1 66  ? -9.641  -15.556 56.131  1.000 151.848 ? 66  LEU AAA CB  1 ? 
ATOM   477  C  CG  . LEU A 1 66  ? -10.693 -15.071 55.133  1.000 156.466 ? 66  LEU AAA CG  1 ? 
ATOM   478  C  CD1 . LEU A 1 66  ? -11.765 -14.240 55.822  1.000 157.283 ? 66  LEU AAA CD1 1 ? 
ATOM   479  C  CD2 . LEU A 1 66  ? -10.044 -14.287 54.001  1.000 158.994 ? 66  LEU AAA CD2 1 ? 
ATOM   480  N  N   . HIS A 1 67  ? -8.131  -17.580 57.808  1.000 143.399 ? 67  HIS AAA N   1 ? 
ATOM   481  C  CA  . HIS A 1 67  ? -7.216  -18.043 58.863  1.000 147.676 ? 67  HIS AAA CA  1 ? 
ATOM   482  C  C   . HIS A 1 67  ? -6.021  -18.797 58.296  1.000 147.009 ? 67  HIS AAA C   1 ? 
ATOM   483  O  O   . HIS A 1 67  ? -4.885  -18.512 58.664  1.000 138.560 ? 67  HIS AAA O   1 ? 
ATOM   484  C  CB  . HIS A 1 67  ? -7.978  -18.913 59.870  1.000 152.064 ? 67  HIS AAA CB  1 ? 
ATOM   485  C  CG  . HIS A 1 67  ? -8.812  -18.125 60.817  1.000 156.500 ? 67  HIS AAA CG  1 ? 
ATOM   486  N  ND1 . HIS A 1 67  ? -8.292  -17.070 61.536  1.000 158.983 ? 67  HIS AAA ND1 1 ? 
ATOM   487  C  CD2 . HIS A 1 67  ? -10.111 -18.231 61.170  1.000 156.819 ? 67  HIS AAA CD2 1 ? 
ATOM   488  C  CE1 . HIS A 1 67  ? -9.235  -16.554 62.291  1.000 161.574 ? 67  HIS AAA CE1 1 ? 
ATOM   489  N  NE2 . HIS A 1 67  ? -10.363 -17.251 62.088  1.000 159.387 ? 67  HIS AAA NE2 1 ? 
ATOM   490  N  N   . THR A 1 68  ? -6.300  -19.767 57.438  1.000 154.587 ? 68  THR AAA N   1 ? 
ATOM   491  C  CA  . THR A 1 68  ? -5.263  -20.657 56.898  1.000 159.559 ? 68  THR AAA CA  1 ? 
ATOM   492  C  C   . THR A 1 68  ? -4.337  -19.785 56.085  1.000 161.364 ? 68  THR AAA C   1 ? 
ATOM   493  O  O   . THR A 1 68  ? -3.121  -19.807 56.286  1.000 167.843 ? 68  THR AAA O   1 ? 
ATOM   494  C  CB  . THR A 1 68  ? -5.848  -21.786 56.036  1.000 160.008 ? 68  THR AAA CB  1 ? 
ATOM   495  O  OG1 . THR A 1 68  ? -7.071  -22.246 56.613  1.000 167.806 ? 68  THR AAA OG1 1 ? 
ATOM   496  C  CG2 . THR A 1 68  ? -4.891  -22.947 55.882  1.000 157.646 ? 68  THR AAA CG2 1 ? 
ATOM   497  N  N   . LEU A 1 69  ? -4.932  -18.983 55.222  1.000 162.293 ? 69  LEU AAA N   1 ? 
ATOM   498  C  CA  . LEU A 1 69  ? -4.136  -18.149 54.307  1.000 157.310 ? 69  LEU AAA CA  1 ? 
ATOM   499  C  C   . LEU A 1 69  ? -3.208  -17.233 55.090  1.000 154.688 ? 69  LEU AAA C   1 ? 
ATOM   500  O  O   . LEU A 1 69  ? -2.007  -17.139 54.794  1.000 149.250 ? 69  LEU AAA O   1 ? 
ATOM   501  C  CB  . LEU A 1 69  ? -5.067  -17.338 53.398  1.000 155.977 ? 69  LEU AAA CB  1 ? 
ATOM   502  C  CG  . LEU A 1 69  ? -5.929  -18.148 52.428  1.000 151.640 ? 69  LEU AAA CG  1 ? 
ATOM   503  C  CD1 . LEU A 1 69  ? -6.920  -17.248 51.711  1.000 151.092 ? 69  LEU AAA CD1 1 ? 
ATOM   504  C  CD2 . LEU A 1 69  ? -5.070  -18.894 51.419  1.000 150.516 ? 69  LEU AAA CD2 1 ? 
ATOM   505  N  N   . PHE A 1 70  ? -3.778  -16.584 56.088  1.000 154.026 ? 70  PHE AAA N   1 ? 
ATOM   506  C  CA  . PHE A 1 70  ? -3.099  -15.539 56.861  1.000 152.683 ? 70  PHE AAA CA  1 ? 
ATOM   507  C  C   . PHE A 1 70  ? -2.014  -16.215 57.674  1.000 148.918 ? 70  PHE AAA C   1 ? 
ATOM   508  O  O   . PHE A 1 70  ? -0.840  -15.853 57.585  1.000 144.888 ? 70  PHE AAA O   1 ? 
ATOM   509  C  CB  . PHE A 1 70  ? -4.099  -14.782 57.741  1.000 159.094 ? 70  PHE AAA CB  1 ? 
ATOM   510  C  CG  . PHE A 1 70  ? -4.944  -13.774 57.002  1.000 165.986 ? 70  PHE AAA CG  1 ? 
ATOM   511  C  CD1 . PHE A 1 70  ? -5.378  -14.017 55.705  1.000 167.197 ? 70  PHE AAA CD1 1 ? 
ATOM   512  C  CD2 . PHE A 1 70  ? -5.320  -12.583 57.608  1.000 164.745 ? 70  PHE AAA CD2 1 ? 
ATOM   513  C  CE1 . PHE A 1 70  ? -6.156  -13.090 55.029  1.000 162.819 ? 70  PHE AAA CE1 1 ? 
ATOM   514  C  CE2 . PHE A 1 70  ? -6.101  -11.658 56.930  1.000 160.796 ? 70  PHE AAA CE2 1 ? 
ATOM   515  C  CZ  . PHE A 1 70  ? -6.516  -11.914 55.643  1.000 161.817 ? 70  PHE AAA CZ  1 ? 
ATOM   516  N  N   . GLY A 1 71  ? -2.425  -17.204 58.448  1.000 150.700 ? 71  GLY AAA N   1 ? 
ATOM   517  C  CA  . GLY A 1 71  ? -1.479  -17.978 59.244  1.000 156.313 ? 71  GLY AAA CA  1 ? 
ATOM   518  C  C   . GLY A 1 71  ? -0.309  -18.427 58.398  1.000 161.692 ? 71  GLY AAA C   1 ? 
ATOM   519  O  O   . GLY A 1 71  ? 0.843   -18.243 58.813  1.000 160.332 ? 71  GLY AAA O   1 ? 
ATOM   520  N  N   . ASP A 1 72  ? -0.605  -18.991 57.224  1.000 173.399 ? 72  ASP AAA N   1 ? 
ATOM   521  C  CA  . ASP A 1 72  ? 0.433   -19.488 56.285  1.000 181.046 ? 72  ASP AAA CA  1 ? 
ATOM   522  C  C   . ASP A 1 72  ? 1.407   -18.380 55.919  1.000 184.118 ? 72  ASP AAA C   1 ? 
ATOM   523  O  O   . ASP A 1 72  ? 2.620   -18.531 56.150  1.000 183.017 ? 72  ASP AAA O   1 ? 
ATOM   524  C  CB  . ASP A 1 72  ? -0.186  -20.050 54.998  1.000 184.307 ? 72  ASP AAA CB  1 ? 
ATOM   525  C  CG  . ASP A 1 72  ? -0.886  -21.393 55.142  1.000 187.759 ? 72  ASP AAA CG  1 ? 
ATOM   526  O  OD1 . ASP A 1 72  ? -0.502  -22.171 56.040  1.000 191.477 ? 72  ASP AAA OD1 1 ? 
ATOM   527  O  OD2 . ASP A 1 72  ? -1.813  -21.653 54.348  1.000 187.475 ? 72  ASP AAA OD2 1 ? 
ATOM   528  N  N   . LYS A 1 73  ? 0.880   -17.303 55.349  1.000 189.798 ? 73  LYS AAA N   1 ? 
ATOM   529  C  CA  . LYS A 1 73  ? 1.724   -16.191 54.887  1.000 193.528 ? 73  LYS AAA CA  1 ? 
ATOM   530  C  C   . LYS A 1 73  ? 2.573   -15.780 56.063  1.000 192.792 ? 73  LYS AAA C   1 ? 
ATOM   531  O  O   . LYS A 1 73  ? 3.797   -15.775 55.958  1.000 198.968 ? 73  LYS AAA O   1 ? 
ATOM   532  C  CB  . LYS A 1 73  ? 0.887   -15.026 54.349  1.000 193.651 ? 73  LYS AAA CB  1 ? 
ATOM   533  C  CG  . LYS A 1 73  ? 0.360   -15.214 52.933  1.000 195.419 ? 73  LYS AAA CG  1 ? 
ATOM   534  C  CD  . LYS A 1 73  ? 1.445   -15.296 51.874  1.000 193.476 ? 73  LYS AAA CD  1 ? 
ATOM   535  C  CE  . LYS A 1 73  ? 0.911   -15.691 50.513  1.000 193.674 ? 73  LYS AAA CE  1 ? 
ATOM   536  N  NZ  . LYS A 1 73  ? 1.961   -16.309 49.670  1.000 191.871 ? 73  LYS AAA NZ  1 ? 
ATOM   537  N  N   . LEU A 1 74  ? 1.911   -15.529 57.176  1.000 186.806 ? 74  LEU AAA N   1 ? 
ATOM   538  C  CA  . LEU A 1 74  ? 2.626   -15.210 58.414  1.000 179.787 ? 74  LEU AAA CA  1 ? 
ATOM   539  C  C   . LEU A 1 74  ? 3.760   -16.197 58.660  1.000 161.814 ? 74  LEU AAA C   1 ? 
ATOM   540  O  O   . LEU A 1 74  ? 4.913   -15.773 58.845  1.000 144.121 ? 74  LEU AAA O   1 ? 
ATOM   541  C  CB  . LEU A 1 74  ? 1.642   -15.160 59.592  1.000 192.375 ? 74  LEU AAA CB  1 ? 
ATOM   542  C  CG  . LEU A 1 74  ? 0.714   -13.943 59.642  1.000 199.475 ? 74  LEU AAA CG  1 ? 
ATOM   543  C  CD1 . LEU A 1 74  ? -0.360  -14.118 60.708  1.000 199.194 ? 74  LEU AAA CD1 1 ? 
ATOM   544  C  CD2 . LEU A 1 74  ? 1.494   -12.660 59.891  1.000 200.115 ? 74  LEU AAA CD2 1 ? 
ATOM   545  N  N   . CYS A 1 75  ? 3.477   -17.480 58.597  1.000 158.725 ? 75  CYS AAA N   1 ? 
ATOM   546  C  CA  . CYS A 1 75  ? 4.514   -18.482 58.888  1.000 160.987 ? 75  CYS AAA CA  1 ? 
ATOM   547  C  C   . CYS A 1 75  ? 5.685   -18.490 57.904  1.000 160.598 ? 75  CYS AAA C   1 ? 
ATOM   548  O  O   . CYS A 1 75  ? 6.603   -19.286 58.114  1.000 161.101 ? 75  CYS AAA O   1 ? 
ATOM   549  C  CB  . CYS A 1 75  ? 3.894   -19.872 58.971  1.000 164.850 ? 75  CYS AAA CB  1 ? 
ATOM   550  S  SG  . CYS A 1 75  ? 2.990   -20.122 60.519  1.000 169.494 ? 75  CYS AAA SG  1 ? 
ATOM   551  N  N   . THR A 1 76  ? 5.677   -17.639 56.884  1.000 165.523 ? 76  THR AAA N   1 ? 
ATOM   552  C  CA  . THR A 1 76  ? 6.776   -17.618 55.896  1.000 169.946 ? 76  THR AAA CA  1 ? 
ATOM   553  C  C   . THR A 1 76  ? 7.928   -16.737 56.389  1.000 176.644 ? 76  THR AAA C   1 ? 
ATOM   554  O  O   . THR A 1 76  ? 8.722   -17.220 57.205  1.000 184.432 ? 76  THR AAA O   1 ? 
ATOM   555  C  CB  . THR A 1 76  ? 6.292   -17.158 54.512  1.000 162.976 ? 76  THR AAA CB  1 ? 
ATOM   556  O  OG1 . THR A 1 76  ? 5.877   -15.792 54.569  1.000 156.098 ? 76  THR AAA OG1 1 ? 
ATOM   557  C  CG2 . THR A 1 76  ? 5.157   -18.000 53.972  1.000 159.036 ? 76  THR AAA CG2 1 ? 
ATOM   558  N  N   . ASP A 1 89  ? 6.701   -22.507 66.972  1.000 152.518 ? 89  ASP AAA N   1 ? 
ATOM   559  C  CA  . ASP A 1 89  ? 5.824   -23.452 67.724  1.000 153.505 ? 89  ASP AAA CA  1 ? 
ATOM   560  C  C   . ASP A 1 89  ? 4.380   -23.351 67.215  1.000 161.715 ? 89  ASP AAA C   1 ? 
ATOM   561  O  O   . ASP A 1 89  ? 3.728   -24.402 67.003  1.000 154.578 ? 89  ASP AAA O   1 ? 
ATOM   562  C  CB  . ASP A 1 89  ? 5.922   -23.222 69.240  1.000 146.098 ? 89  ASP AAA CB  1 ? 
ATOM   563  C  CG  . ASP A 1 89  ? 5.519   -21.836 69.734  1.000 137.227 ? 89  ASP AAA CG  1 ? 
ATOM   564  O  OD1 . ASP A 1 89  ? 5.390   -20.918 68.899  1.000 134.551 ? 89  ASP AAA OD1 1 ? 
ATOM   565  O  OD2 . ASP A 1 89  ? 5.344   -21.679 70.959  1.000 125.214 ? 89  ASP AAA OD2 1 ? 
ATOM   566  N  N   . CYS A 1 90  ? 3.882   -22.125 67.042  1.000 167.975 ? 90  CYS AAA N   1 ? 
ATOM   567  C  CA  . CYS A 1 90  ? 2.574   -21.848 66.384  1.000 164.316 ? 90  CYS AAA CA  1 ? 
ATOM   568  C  C   . CYS A 1 90  ? 2.549   -22.459 64.993  1.000 167.856 ? 90  CYS AAA C   1 ? 
ATOM   569  O  O   . CYS A 1 90  ? 1.592   -23.176 64.625  1.000 173.442 ? 90  CYS AAA O   1 ? 
ATOM   570  C  CB  . CYS A 1 90  ? 2.310   -20.350 66.274  1.000 157.743 ? 90  CYS AAA CB  1 ? 
ATOM   571  S  SG  . CYS A 1 90  ? 1.887   -19.555 67.847  1.000 143.435 ? 90  CYS AAA SG  1 ? 
ATOM   572  N  N   . CYS A 1 91  ? 3.590   -22.174 64.234  1.000 166.295 ? 91  CYS AAA N   1 ? 
ATOM   573  C  CA  . CYS A 1 91  ? 3.657   -22.567 62.822  1.000 166.180 ? 91  CYS AAA CA  1 ? 
ATOM   574  C  C   . CYS A 1 91  ? 3.812   -24.066 62.660  1.000 161.684 ? 91  CYS AAA C   1 ? 
ATOM   575  O  O   . CYS A 1 91  ? 3.498   -24.572 61.579  1.000 161.265 ? 91  CYS AAA O   1 ? 
ATOM   576  C  CB  . CYS A 1 91  ? 4.808   -21.841 62.138  1.000 167.428 ? 91  CYS AAA CB  1 ? 
ATOM   577  S  SG  . CYS A 1 91  ? 4.466   -20.078 61.918  1.000 168.599 ? 91  CYS AAA SG  1 ? 
ATOM   578  N  N   . ALA A 1 92  ? 4.270   -24.732 63.710  1.000 155.257 ? 92  ALA AAA N   1 ? 
ATOM   579  C  CA  . ALA A 1 92  ? 4.329   -26.199 63.740  1.000 150.046 ? 92  ALA AAA CA  1 ? 
ATOM   580  C  C   . ALA A 1 92  ? 2.931   -26.782 63.895  1.000 150.270 ? 92  ALA AAA C   1 ? 
ATOM   581  O  O   . ALA A 1 92  ? 2.771   -28.019 63.831  1.000 154.463 ? 92  ALA AAA O   1 ? 
ATOM   582  C  CB  . ALA A 1 92  ? 5.237   -26.651 64.858  1.000 144.847 ? 92  ALA AAA CB  1 ? 
ATOM   583  N  N   . LYS A 1 93  ? 1.949   -25.898 64.082  1.000 151.212 ? 93  LYS AAA N   1 ? 
ATOM   584  C  CA  . LYS A 1 93  ? 0.562   -26.302 64.376  1.000 156.175 ? 93  LYS AAA CA  1 ? 
ATOM   585  C  C   . LYS A 1 93  ? -0.385  -25.888 63.265  1.000 156.836 ? 93  LYS AAA C   1 ? 
ATOM   586  O  O   . LYS A 1 93  ? -0.049  -25.079 62.376  1.000 150.197 ? 93  LYS AAA O   1 ? 
ATOM   587  C  CB  . LYS A 1 93  ? 0.145   -25.755 65.746  1.000 156.794 ? 93  LYS AAA CB  1 ? 
ATOM   588  C  CG  . LYS A 1 93  ? 0.743   -26.524 66.916  1.000 154.065 ? 93  LYS AAA CG  1 ? 
ATOM   589  C  CD  . LYS A 1 93  ? 0.919   -25.722 68.180  1.000 148.945 ? 93  LYS AAA CD  1 ? 
ATOM   590  C  CE  . LYS A 1 93  ? 1.957   -26.341 69.090  1.000 148.470 ? 93  LYS AAA CE  1 ? 
ATOM   591  N  NZ  . LYS A 1 93  ? 2.128   -25.557 70.333  1.000 150.708 ? 93  LYS AAA NZ  1 ? 
ATOM   592  N  N   . GLN A 1 94  ? -1.572  -26.457 63.337  1.000 159.560 ? 94  GLN AAA N   1 ? 
ATOM   593  C  CA  . GLN A 1 94  ? -2.540  -26.310 62.251  1.000 160.567 ? 94  GLN AAA CA  1 ? 
ATOM   594  C  C   . GLN A 1 94  ? -3.876  -25.851 62.780  1.000 154.734 ? 94  GLN AAA C   1 ? 
ATOM   595  O  O   . GLN A 1 94  ? -4.152  -25.843 63.996  1.000 154.567 ? 94  GLN AAA O   1 ? 
ATOM   596  C  CB  . GLN A 1 94  ? -2.669  -27.615 61.469  1.000 165.655 ? 94  GLN AAA CB  1 ? 
ATOM   597  C  CG  . GLN A 1 94  ? -1.950  -27.569 60.132  1.000 173.098 ? 94  GLN AAA CG  1 ? 
ATOM   598  C  CD  . GLN A 1 94  ? -1.690  -28.952 59.598  1.000 183.787 ? 94  GLN AAA CD  1 ? 
ATOM   599  O  OE1 . GLN A 1 94  ? -0.940  -29.723 60.189  1.000 198.699 ? 94  GLN AAA OE1 1 ? 
ATOM   600  N  NE2 . GLN A 1 94  ? -2.313  -29.274 58.476  1.000 192.317 ? 94  GLN AAA NE2 1 ? 
ATOM   601  N  N   . GLU A 1 95  ? -4.690  -25.481 61.823  1.000 146.563 ? 95  GLU AAA N   1 ? 
ATOM   602  C  CA  . GLU A 1 95  ? -5.972  -24.860 62.096  1.000 140.256 ? 95  GLU AAA CA  1 ? 
ATOM   603  C  C   . GLU A 1 95  ? -6.825  -25.917 62.772  1.000 138.626 ? 95  GLU AAA C   1 ? 
ATOM   604  O  O   . GLU A 1 95  ? -6.770  -27.096 62.418  1.000 132.331 ? 95  GLU AAA O   1 ? 
ATOM   605  C  CB  . GLU A 1 95  ? -6.594  -24.354 60.790  1.000 137.199 ? 95  GLU AAA CB  1 ? 
ATOM   606  C  CG  . GLU A 1 95  ? -7.118  -22.934 60.871  1.000 139.648 ? 95  GLU AAA CG  1 ? 
ATOM   607  C  CD  . GLU A 1 95  ? -6.140  -21.938 61.471  1.000 139.996 ? 95  GLU AAA CD  1 ? 
ATOM   608  O  OE1 . GLU A 1 95  ? -4.934  -22.031 61.169  1.000 133.958 ? 95  GLU AAA OE1 1 ? 
ATOM   609  O  OE2 . GLU A 1 95  ? -6.588  -21.086 62.251  1.000 146.312 ? 95  GLU AAA OE2 1 ? 
ATOM   610  N  N   . PRO A 1 96  ? -7.601  -25.522 63.796  1.000 145.284 ? 96  PRO AAA N   1 ? 
ATOM   611  C  CA  . PRO A 1 96  ? -7.589  -24.158 64.340  1.000 147.271 ? 96  PRO AAA CA  1 ? 
ATOM   612  C  C   . PRO A 1 96  ? -6.511  -23.900 65.400  1.000 147.177 ? 96  PRO AAA C   1 ? 
ATOM   613  O  O   . PRO A 1 96  ? -6.222  -22.747 65.679  1.000 146.787 ? 96  PRO AAA O   1 ? 
ATOM   614  C  CB  . PRO A 1 96  ? -8.988  -24.003 64.958  1.000 149.726 ? 96  PRO AAA CB  1 ? 
ATOM   615  C  CG  . PRO A 1 96  ? -9.424  -25.416 65.314  1.000 152.744 ? 96  PRO AAA CG  1 ? 
ATOM   616  C  CD  . PRO A 1 96  ? -8.642  -26.355 64.415  1.000 150.072 ? 96  PRO AAA CD  1 ? 
ATOM   617  N  N   . GLU A 1 97  ? -5.926  -24.950 65.966  1.000 150.742 ? 97  GLU AAA N   1 ? 
ATOM   618  C  CA  . GLU A 1 97  ? -5.017  -24.796 67.132  1.000 151.564 ? 97  GLU AAA CA  1 ? 
ATOM   619  C  C   . GLU A 1 97  ? -4.113  -23.614 66.829  1.000 148.736 ? 97  GLU AAA C   1 ? 
ATOM   620  O  O   . GLU A 1 97  ? -4.059  -22.634 67.578  1.000 152.500 ? 97  GLU AAA O   1 ? 
ATOM   621  C  CB  . GLU A 1 97  ? -4.200  -26.072 67.371  1.000 153.802 ? 97  GLU AAA CB  1 ? 
ATOM   622  C  CG  . GLU A 1 97  ? -5.015  -27.263 67.867  1.000 152.168 ? 97  GLU AAA CG  1 ? 
ATOM   623  C  CD  . GLU A 1 97  ? -5.641  -28.169 66.815  1.000 148.202 ? 97  GLU AAA CD  1 ? 
ATOM   624  O  OE1 . GLU A 1 97  ? -5.335  -28.004 65.616  1.000 152.205 ? 97  GLU AAA OE1 1 ? 
ATOM   625  O  OE2 . GLU A 1 97  ? -6.436  -29.049 67.203  1.000 136.008 ? 97  GLU AAA OE2 1 ? 
ATOM   626  N  N   . ARG A 1 98  ? -3.482  -23.702 65.679  1.000 142.200 ? 98  ARG AAA N   1 ? 
ATOM   627  C  CA  . ARG A 1 98  ? -2.544  -22.683 65.193  1.000 136.176 ? 98  ARG AAA CA  1 ? 
ATOM   628  C  C   . ARG A 1 98  ? -3.019  -21.250 65.446  1.000 125.091 ? 98  ARG AAA C   1 ? 
ATOM   629  O  O   . ARG A 1 98  ? -2.285  -20.438 66.013  1.000 111.163 ? 98  ARG AAA O   1 ? 
ATOM   630  C  CB  . ARG A 1 98  ? -2.346  -22.878 63.691  1.000 143.505 ? 98  ARG AAA CB  1 ? 
ATOM   631  C  CG  . ARG A 1 98  ? -1.339  -21.929 63.061  1.000 150.696 ? 98  ARG AAA CG  1 ? 
ATOM   632  C  CD  . ARG A 1 98  ? -1.839  -21.464 61.709  1.000 157.354 ? 98  ARG AAA CD  1 ? 
ATOM   633  N  NE  . ARG A 1 98  ? -0.824  -21.593 60.676  1.000 163.449 ? 98  ARG AAA NE  1 ? 
ATOM   634  C  CZ  . ARG A 1 98  ? -1.071  -21.669 59.372  1.000 164.078 ? 98  ARG AAA CZ  1 ? 
ATOM   635  N  NH1 . ARG A 1 98  ? -2.314  -21.630 58.914  1.000 168.568 ? 98  ARG AAA NH1 1 ? 
ATOM   636  N  NH2 . ARG A 1 98  ? -0.064  -21.786 58.526  1.000 159.346 ? 98  ARG AAA NH2 1 ? 
ATOM   637  N  N   . ASN A 1 99  ? -4.215  -20.921 64.993  1.000 122.166 ? 99  ASN AAA N   1 ? 
ATOM   638  C  CA  . ASN A 1 99  ? -4.732  -19.549 65.139  1.000 121.728 ? 99  ASN AAA CA  1 ? 
ATOM   639  C  C   . ASN A 1 99  ? -4.807  -19.198 66.616  1.000 126.703 ? 99  ASN AAA C   1 ? 
ATOM   640  O  O   . ASN A 1 99  ? -4.272  -18.162 67.042  1.000 136.340 ? 99  ASN AAA O   1 ? 
ATOM   641  C  CB  . ASN A 1 99  ? -6.083  -19.380 64.446  1.000 121.739 ? 99  ASN AAA CB  1 ? 
ATOM   642  C  CG  . ASN A 1 99  ? -6.434  -17.932 64.186  1.000 122.400 ? 99  ASN AAA CG  1 ? 
ATOM   643  O  OD1 . ASN A 1 99  ? -7.449  -17.441 64.672  1.000 128.305 ? 99  ASN AAA OD1 1 ? 
ATOM   644  N  ND2 . ASN A 1 99  ? -5.599  -17.246 63.421  1.000 115.493 ? 99  ASN AAA ND2 1 ? 
ATOM   645  N  N   . GLU A 1 100 ? -5.433  -20.077 67.383  1.000 125.659 ? 100 GLU AAA N   1 ? 
ATOM   646  C  CA  . GLU A 1 100 ? -5.580  -19.887 68.836  1.000 124.084 ? 100 GLU AAA CA  1 ? 
ATOM   647  C  C   . GLU A 1 100 ? -4.220  -19.607 69.440  1.000 121.907 ? 100 GLU AAA C   1 ? 
ATOM   648  O  O   . GLU A 1 100 ? -4.094  -18.761 70.332  1.000 126.891 ? 100 GLU AAA O   1 ? 
ATOM   649  C  CB  . GLU A 1 100 ? -6.240  -21.103 69.490  1.000 128.598 ? 100 GLU AAA CB  1 ? 
ATOM   650  C  CG  . GLU A 1 100 ? -7.675  -21.344 69.038  1.000 137.748 ? 100 GLU AAA CG  1 ? 
ATOM   651  C  CD  . GLU A 1 100 ? -8.686  -20.272 69.422  1.000 143.688 ? 100 GLU AAA CD  1 ? 
ATOM   652  O  OE1 . GLU A 1 100 ? -8.313  -19.349 70.173  1.000 148.574 ? 100 GLU AAA OE1 1 ? 
ATOM   653  O  OE2 . GLU A 1 100 ? -9.852  -20.368 68.973  1.000 144.613 ? 100 GLU AAA OE2 1 ? 
ATOM   654  N  N   . CYS A 1 101 ? -3.233  -20.311 68.923  1.000 119.940 ? 101 CYS AAA N   1 ? 
ATOM   655  C  CA  . CYS A 1 101 ? -1.831  -20.027 69.223  1.000 123.027 ? 101 CYS AAA CA  1 ? 
ATOM   656  C  C   . CYS A 1 101 ? -1.551  -18.530 69.098  1.000 117.463 ? 101 CYS AAA C   1 ? 
ATOM   657  O  O   . CYS A 1 101 ? -1.309  -17.888 70.125  1.000 123.754 ? 101 CYS AAA O   1 ? 
ATOM   658  C  CB  . CYS A 1 101 ? -0.892  -20.805 68.302  1.000 131.594 ? 101 CYS AAA CB  1 ? 
ATOM   659  S  SG  . CYS A 1 101 ? 0.815   -20.940 68.902  1.000 143.984 ? 101 CYS AAA SG  1 ? 
ATOM   660  N  N   . PHE A 1 102 ? -1.610  -17.984 67.886  1.000 108.618 ? 102 PHE AAA N   1 ? 
ATOM   661  C  CA  . PHE A 1 102 ? -1.319  -16.547 67.642  1.000 106.722 ? 102 PHE AAA CA  1 ? 
ATOM   662  C  C   . PHE A 1 102 ? -2.171  -15.650 68.521  1.000 106.688 ? 102 PHE AAA C   1 ? 
ATOM   663  O  O   . PHE A 1 102 ? -1.673  -14.678 69.110  1.000 101.197 ? 102 PHE AAA O   1 ? 
ATOM   664  C  CB  . PHE A 1 102 ? -1.640  -16.155 66.199  1.000 108.165 ? 102 PHE AAA CB  1 ? 
ATOM   665  C  CG  . PHE A 1 102 ? -0.695  -16.692 65.159  1.000 110.034 ? 102 PHE AAA CG  1 ? 
ATOM   666  C  CD1 . PHE A 1 102 ? 0.607   -16.225 65.082  1.000 111.644 ? 102 PHE AAA CD1 1 ? 
ATOM   667  C  CD2 . PHE A 1 102 ? -1.115  -17.641 64.242  1.000 110.833 ? 102 PHE AAA CD2 1 ? 
ATOM   668  C  CE1 . PHE A 1 102 ? 1.478   -16.710 64.120  1.000 110.894 ? 102 PHE AAA CE1 1 ? 
ATOM   669  C  CE2 . PHE A 1 102 ? -0.243  -18.124 63.279  1.000 111.851 ? 102 PHE AAA CE2 1 ? 
ATOM   670  C  CZ  . PHE A 1 102 ? 1.051   -17.659 63.220  1.000 110.448 ? 102 PHE AAA CZ  1 ? 
ATOM   671  N  N   . LEU A 1 103 ? -3.453  -15.961 68.570  1.000 115.631 ? 103 LEU AAA N   1 ? 
ATOM   672  C  CA  . LEU A 1 103 ? -4.384  -15.246 69.455  1.000 125.883 ? 103 LEU AAA CA  1 ? 
ATOM   673  C  C   . LEU A 1 103 ? -3.875  -15.174 70.893  1.000 134.601 ? 103 LEU AAA C   1 ? 
ATOM   674  O  O   . LEU A 1 103 ? -3.984  -14.124 71.529  1.000 137.950 ? 103 LEU AAA O   1 ? 
ATOM   675  C  CB  . LEU A 1 103 ? -5.759  -15.923 69.398  1.000 130.064 ? 103 LEU AAA CB  1 ? 
ATOM   676  C  CG  . LEU A 1 103 ? -6.804  -15.209 68.543  1.000 131.677 ? 103 LEU AAA CG  1 ? 
ATOM   677  C  CD1 . LEU A 1 103 ? -7.999  -16.114 68.290  1.000 130.370 ? 103 LEU AAA CD1 1 ? 
ATOM   678  C  CD2 . LEU A 1 103 ? -7.248  -13.910 69.204  1.000 136.829 ? 103 LEU AAA CD2 1 ? 
ATOM   679  N  N   . GLN A 1 104 ? -3.347  -16.277 71.398  1.000 140.323 ? 104 GLN AAA N   1 ? 
ATOM   680  C  CA  . GLN A 1 104 ? -2.788  -16.311 72.760  1.000 136.839 ? 104 GLN AAA CA  1 ? 
ATOM   681  C  C   . GLN A 1 104 ? -1.347  -15.843 72.829  1.000 142.459 ? 104 GLN AAA C   1 ? 
ATOM   682  O  O   . GLN A 1 104 ? -0.851  -15.672 73.950  1.000 144.446 ? 104 GLN AAA O   1 ? 
ATOM   683  C  CB  . GLN A 1 104 ? -2.872  -17.731 73.318  1.000 129.046 ? 104 GLN AAA CB  1 ? 
ATOM   684  C  CG  . GLN A 1 104 ? -4.299  -18.220 73.505  1.000 127.877 ? 104 GLN AAA CG  1 ? 
ATOM   685  C  CD  . GLN A 1 104 ? -4.362  -19.723 73.588  1.000 129.105 ? 104 GLN AAA CD  1 ? 
ATOM   686  O  OE1 . GLN A 1 104 ? -3.564  -20.432 72.976  1.000 124.301 ? 104 GLN AAA OE1 1 ? 
ATOM   687  N  NE2 . GLN A 1 104 ? -5.318  -20.224 74.352  1.000 134.326 ? 104 GLN AAA NE2 1 ? 
ATOM   688  N  N   . HIS A 1 105 ? -0.677  -15.660 71.699  1.000 147.593 ? 105 HIS AAA N   1 ? 
ATOM   689  C  CA  . HIS A 1 105 ? 0.678   -15.070 71.726  1.000 150.030 ? 105 HIS AAA CA  1 ? 
ATOM   690  C  C   . HIS A 1 105 ? 0.632   -13.543 71.629  1.000 139.211 ? 105 HIS AAA C   1 ? 
ATOM   691  O  O   . HIS A 1 105 ? 1.707   -12.937 71.613  1.000 142.295 ? 105 HIS AAA O   1 ? 
ATOM   692  C  CB  . HIS A 1 105 ? 1.577   -15.670 70.630  1.000 162.992 ? 105 HIS AAA CB  1 ? 
ATOM   693  C  CG  . HIS A 1 105 ? 2.120   -17.025 70.948  1.000 175.048 ? 105 HIS AAA CG  1 ? 
ATOM   694  N  ND1 . HIS A 1 105 ? 3.140   -17.241 71.863  1.000 177.065 ? 105 HIS AAA ND1 1 ? 
ATOM   695  C  CD2 . HIS A 1 105 ? 1.800   -18.237 70.456  1.000 179.268 ? 105 HIS AAA CD2 1 ? 
ATOM   696  C  CE1 . HIS A 1 105 ? 3.409   -18.532 71.923  1.000 177.180 ? 105 HIS AAA CE1 1 ? 
ATOM   697  N  NE2 . HIS A 1 105 ? 2.603   -19.164 71.065  1.000 178.452 ? 105 HIS AAA NE2 1 ? 
ATOM   698  N  N   . LYS A 1 106 ? -0.551  -12.933 71.591  1.000 128.730 ? 106 LYS AAA N   1 ? 
ATOM   699  C  CA  . LYS A 1 106 ? -0.708  -11.450 71.597  1.000 123.371 ? 106 LYS AAA CA  1 ? 
ATOM   700  C  C   . LYS A 1 106 ? -0.148  -10.816 72.873  1.000 120.056 ? 106 LYS AAA C   1 ? 
ATOM   701  O  O   . LYS A 1 106 ? -0.525  -11.256 73.976  1.000 120.490 ? 106 LYS AAA O   1 ? 
ATOM   702  C  CB  . LYS A 1 106 ? -2.187  -11.050 71.524  1.000 123.567 ? 106 LYS AAA CB  1 ? 
ATOM   703  C  CG  . LYS A 1 106 ? -2.820  -11.073 70.140  1.000 123.056 ? 106 LYS AAA CG  1 ? 
ATOM   704  C  CD  . LYS A 1 106 ? -4.220  -10.486 70.117  1.000 119.660 ? 106 LYS AAA CD  1 ? 
ATOM   705  C  CE  . LYS A 1 106 ? -4.787  -10.353 68.720  1.000 118.397 ? 106 LYS AAA CE  1 ? 
ATOM   706  N  NZ  . LYS A 1 106 ? -6.126  -9.719  68.734  1.000 119.785 ? 106 LYS AAA NZ  1 ? 
ATOM   707  N  N   . ASP A 1 107 ? 0.653   -9.761  72.736  1.000 116.191 ? 107 ASP AAA N   1 ? 
ATOM   708  C  CA  . ASP A 1 107 ? 1.232   -9.076  73.921  1.000 113.384 ? 107 ASP AAA CA  1 ? 
ATOM   709  C  C   . ASP A 1 107 ? 0.588   -7.713  74.166  1.000 117.136 ? 107 ASP AAA C   1 ? 
ATOM   710  O  O   . ASP A 1 107 ? 0.686   -6.807  73.315  1.000 124.697 ? 107 ASP AAA O   1 ? 
ATOM   711  C  CB  . ASP A 1 107 ? 2.753   -8.964  73.814  1.000 109.084 ? 107 ASP AAA CB  1 ? 
ATOM   712  C  CG  . ASP A 1 107 ? 3.431   -8.930  75.173  1.000 106.056 ? 107 ASP AAA CG  1 ? 
ATOM   713  O  OD1 . ASP A 1 107 ? 2.794   -8.465  76.137  1.000 103.108 ? 107 ASP AAA OD1 1 ? 
ATOM   714  O  OD2 . ASP A 1 107 ? 4.579   -9.392  75.263  1.000 107.855 ? 107 ASP AAA OD2 1 ? 
ATOM   715  N  N   . ASP A 1 108 ? 0.027   -7.550  75.358  1.000 122.183 ? 108 ASP AAA N   1 ? 
ATOM   716  C  CA  . ASP A 1 108 ? -0.665  -6.302  75.743  1.000 128.580 ? 108 ASP AAA CA  1 ? 
ATOM   717  C  C   . ASP A 1 108 ? 0.315   -5.199  76.085  1.000 134.782 ? 108 ASP AAA C   1 ? 
ATOM   718  O  O   . ASP A 1 108 ? -0.074  -4.021  76.092  1.000 142.805 ? 108 ASP AAA O   1 ? 
ATOM   719  C  CB  . ASP A 1 108 ? -1.571  -6.528  76.954  1.000 129.720 ? 108 ASP AAA CB  1 ? 
ATOM   720  C  CG  . ASP A 1 108 ? -2.877  -7.210  76.606  1.000 132.310 ? 108 ASP AAA CG  1 ? 
ATOM   721  O  OD1 . ASP A 1 108 ? -3.649  -6.617  75.828  1.000 137.785 ? 108 ASP AAA OD1 1 ? 
ATOM   722  O  OD2 . ASP A 1 108 ? -3.103  -8.330  77.108  1.000 134.142 ? 108 ASP AAA OD2 1 ? 
ATOM   723  N  N   . ASN A 1 109 ? 1.548   -5.572  76.383  1.000 133.079 ? 109 ASN AAA N   1 ? 
ATOM   724  C  CA  . ASN A 1 109 ? 2.526   -4.594  76.878  1.000 123.994 ? 109 ASN AAA CA  1 ? 
ATOM   725  C  C   . ASN A 1 109 ? 3.876   -4.924  76.276  1.000 119.901 ? 109 ASN AAA C   1 ? 
ATOM   726  O  O   . ASN A 1 109 ? 4.744   -5.413  76.989  1.000 113.135 ? 109 ASN AAA O   1 ? 
ATOM   727  C  CB  . ASN A 1 109 ? 2.552   -4.603  78.412  1.000 120.612 ? 109 ASN AAA CB  1 ? 
ATOM   728  C  CG  . ASN A 1 109 ? 3.463   -3.561  79.026  1.000 120.867 ? 109 ASN AAA CG  1 ? 
ATOM   729  O  OD1 . ASN A 1 109 ? 3.425   -3.340  80.235  1.000 118.214 ? 109 ASN AAA OD1 1 ? 
ATOM   730  N  ND2 . ASN A 1 109 ? 4.288   -2.922  78.212  1.000 122.449 ? 109 ASN AAA ND2 1 ? 
ATOM   731  N  N   . PRO A 1 110 ? 4.062   -4.693  74.959  1.000 124.793 ? 110 PRO AAA N   1 ? 
ATOM   732  C  CA  . PRO A 1 110 ? 5.309   -5.068  74.304  1.000 132.775 ? 110 PRO AAA CA  1 ? 
ATOM   733  C  C   . PRO A 1 110 ? 6.510   -4.255  74.800  1.000 144.157 ? 110 PRO AAA C   1 ? 
ATOM   734  O  O   . PRO A 1 110 ? 6.350   -3.095  75.147  1.000 152.160 ? 110 PRO AAA O   1 ? 
ATOM   735  C  CB  . PRO A 1 110 ? 5.075   -4.766  72.812  1.000 128.560 ? 110 PRO AAA CB  1 ? 
ATOM   736  C  CG  . PRO A 1 110 ? 3.577   -4.559  72.678  1.000 128.139 ? 110 PRO AAA CG  1 ? 
ATOM   737  C  CD  . PRO A 1 110 ? 3.109   -4.065  74.032  1.000 126.401 ? 110 PRO AAA CD  1 ? 
ATOM   738  N  N   . ASN A 1 111 ? 7.694   -4.868  74.796  1.000 150.613 ? 111 ASN AAA N   1 ? 
ATOM   739  C  CA  . ASN A 1 111 ? 8.962   -4.136  75.032  1.000 150.134 ? 111 ASN AAA CA  1 ? 
ATOM   740  C  C   . ASN A 1 111 ? 9.333   -3.334  73.781  1.000 160.437 ? 111 ASN AAA C   1 ? 
ATOM   741  O  O   . ASN A 1 111 ? 10.541  -3.176  73.504  1.000 169.887 ? 111 ASN AAA O   1 ? 
ATOM   742  C  CB  . ASN A 1 111 ? 10.091  -5.080  75.456  1.000 138.626 ? 111 ASN AAA CB  1 ? 
ATOM   743  N  N   . LEU A 1 112 ? 8.333   -2.803  73.075  1.000 166.440 ? 112 LEU AAA N   1 ? 
ATOM   744  C  CA  . LEU A 1 112 ? 8.517   -1.989  71.853  1.000 167.992 ? 112 LEU AAA CA  1 ? 
ATOM   745  C  C   . LEU A 1 112 ? 8.899   -0.569  72.241  1.000 174.121 ? 112 LEU AAA C   1 ? 
ATOM   746  O  O   . LEU A 1 112 ? 8.278   0.020   73.133  1.000 167.937 ? 112 LEU AAA O   1 ? 
ATOM   747  C  CB  . LEU A 1 112 ? 7.222   -1.969  71.029  1.000 161.699 ? 112 LEU AAA CB  1 ? 
ATOM   748  C  CG  . LEU A 1 112 ? 6.953   -3.171  70.123  1.000 160.872 ? 112 LEU AAA CG  1 ? 
ATOM   749  C  CD1 . LEU A 1 112 ? 5.737   -2.900  69.252  1.000 161.912 ? 112 LEU AAA CD1 1 ? 
ATOM   750  C  CD2 . LEU A 1 112 ? 8.152   -3.506  69.247  1.000 162.668 ? 112 LEU AAA CD2 1 ? 
ATOM   751  N  N   . PRO A 1 113 ? 9.891   0.006   71.518  1.000 178.410 ? 113 PRO AAA N   1 ? 
ATOM   752  C  CA  . PRO A 1 113 ? 10.335  1.381   71.715  1.000 172.458 ? 113 PRO AAA CA  1 ? 
ATOM   753  C  C   . PRO A 1 113 ? 9.202   2.365   71.969  1.000 167.904 ? 113 PRO AAA C   1 ? 
ATOM   754  O  O   . PRO A 1 113 ? 8.147   2.244   71.386  1.000 164.940 ? 113 PRO AAA O   1 ? 
ATOM   755  C  CB  . PRO A 1 113 ? 10.990  1.740   70.370  1.000 174.125 ? 113 PRO AAA CB  1 ? 
ATOM   756  C  CG  . PRO A 1 113 ? 11.514  0.425   69.830  1.000 175.794 ? 113 PRO AAA CG  1 ? 
ATOM   757  C  CD  . PRO A 1 113 ? 10.635  -0.654  70.430  1.000 178.002 ? 113 PRO AAA CD  1 ? 
ATOM   758  N  N   . ARG A 1 114 ? 9.471   3.342   72.817  1.000 165.754 ? 114 ARG AAA N   1 ? 
ATOM   759  C  CA  . ARG A 1 114 ? 8.542   4.451   73.033  1.000 167.016 ? 114 ARG AAA CA  1 ? 
ATOM   760  C  C   . ARG A 1 114 ? 8.272   5.029   71.652  1.000 168.479 ? 114 ARG AAA C   1 ? 
ATOM   761  O  O   . ARG A 1 114 ? 9.181   5.001   70.807  1.000 171.434 ? 114 ARG AAA O   1 ? 
ATOM   762  C  CB  . ARG A 1 114 ? 9.128   5.496   73.989  1.000 162.374 ? 114 ARG AAA CB  1 ? 
ATOM   763  N  N   . LEU A 1 115 ? 7.060   5.527   71.443  1.000 174.216 ? 115 LEU AAA N   1 ? 
ATOM   764  C  CA  . LEU A 1 115 ? 6.641   6.169   70.170  1.000 182.707 ? 115 LEU AAA CA  1 ? 
ATOM   765  C  C   . LEU A 1 115 ? 6.828   7.683   70.316  1.000 185.220 ? 115 LEU AAA C   1 ? 
ATOM   766  O  O   . LEU A 1 115 ? 6.289   8.248   71.288  1.000 179.717 ? 115 LEU AAA O   1 ? 
ATOM   767  C  CB  . LEU A 1 115 ? 5.184   5.792   69.877  1.000 189.812 ? 115 LEU AAA CB  1 ? 
ATOM   768  C  CG  . LEU A 1 115 ? 4.717   5.972   68.432  1.000 191.830 ? 115 LEU AAA CG  1 ? 
ATOM   769  C  CD1 . LEU A 1 115 ? 5.614   5.222   67.456  1.000 187.496 ? 115 LEU AAA CD1 1 ? 
ATOM   770  C  CD2 . LEU A 1 115 ? 3.273   5.516   68.279  1.000 197.254 ? 115 LEU AAA CD2 1 ? 
ATOM   771  N  N   . VAL A 1 116 ? 7.592   8.302   69.409  1.000 194.077 ? 116 VAL AAA N   1 ? 
ATOM   772  C  CA  . VAL A 1 116 ? 7.940   9.755   69.466  1.000 203.796 ? 116 VAL AAA CA  1 ? 
ATOM   773  C  C   . VAL A 1 116 ? 7.957   10.343  68.048  1.000 215.813 ? 116 VAL AAA C   1 ? 
ATOM   774  O  O   . VAL A 1 116 ? 8.670   9.825   67.171  1.000 220.600 ? 116 VAL AAA O   1 ? 
ATOM   775  C  CB  . VAL A 1 116 ? 9.273   9.990   70.204  1.000 201.056 ? 116 VAL AAA CB  1 ? 
ATOM   776  C  CG1 . VAL A 1 116 ? 10.457  9.339   69.502  1.000 196.651 ? 116 VAL AAA CG1 1 ? 
ATOM   777  C  CG2 . VAL A 1 116 ? 9.533   11.472  70.433  1.000 199.982 ? 116 VAL AAA CG2 1 ? 
ATOM   778  N  N   . ARG A 1 117 ? 7.257   11.463  67.849  1.000 225.534 ? 117 ARG AAA N   1 ? 
ATOM   779  C  CA  . ARG A 1 117 ? 7.110   12.113  66.523  1.000 231.145 ? 117 ARG AAA CA  1 ? 
ATOM   780  C  C   . ARG A 1 117 ? 8.350   12.946  66.259  1.000 241.401 ? 117 ARG AAA C   1 ? 
ATOM   781  O  O   . ARG A 1 117 ? 8.630   13.884  67.002  1.000 234.776 ? 117 ARG AAA O   1 ? 
ATOM   782  C  CB  . ARG A 1 117 ? 5.862   13.000  66.486  1.000 229.925 ? 117 ARG AAA CB  1 ? 
ATOM   783  C  CG  . ARG A 1 117 ? 4.566   12.272  66.814  1.000 235.346 ? 117 ARG AAA CG  1 ? 
ATOM   784  C  CD  . ARG A 1 117 ? 3.385   13.192  67.079  1.000 245.497 ? 117 ARG AAA CD  1 ? 
ATOM   785  N  NE  . ARG A 1 117 ? 3.582   14.095  68.213  1.000 258.027 ? 117 ARG AAA NE  1 ? 
ATOM   786  C  CZ  . ARG A 1 117 ? 2.612   14.623  68.965  1.000 259.678 ? 117 ARG AAA CZ  1 ? 
ATOM   787  N  NH1 . ARG A 1 117 ? 1.341   14.335  68.735  1.000 255.148 ? 117 ARG AAA NH1 1 ? 
ATOM   788  N  NH2 . ARG A 1 117 ? 2.921   15.435  69.962  1.000 261.172 ? 117 ARG AAA NH2 1 ? 
ATOM   789  N  N   . PRO A 1 118 ? 9.128   12.624  65.208  1.000 254.938 ? 118 PRO AAA N   1 ? 
ATOM   790  C  CA  . PRO A 1 118 ? 10.208  13.515  64.805  1.000 248.640 ? 118 PRO AAA CA  1 ? 
ATOM   791  C  C   . PRO A 1 118 ? 9.685   14.864  64.315  1.000 234.281 ? 118 PRO AAA C   1 ? 
ATOM   792  O  O   . PRO A 1 118 ? 8.525   14.980  63.967  1.000 247.388 ? 118 PRO AAA O   1 ? 
ATOM   793  C  CB  . PRO A 1 118 ? 10.916  12.775  63.655  1.000 255.007 ? 118 PRO AAA CB  1 ? 
ATOM   794  C  CG  . PRO A 1 118 ? 10.389  11.350  63.715  1.000 258.705 ? 118 PRO AAA CG  1 ? 
ATOM   795  C  CD  . PRO A 1 118 ? 9.009   11.448  64.332  1.000 258.668 ? 118 PRO AAA CD  1 ? 
ATOM   796  N  N   . GLU A 1 119 ? 10.561  15.861  64.275  1.000 206.513 ? 119 GLU AAA N   1 ? 
ATOM   797  C  CA  . GLU A 1 119 ? 10.135  17.258  64.051  1.000 189.385 ? 119 GLU AAA CA  1 ? 
ATOM   798  C  C   . GLU A 1 119 ? 9.102   17.340  62.932  1.000 170.421 ? 119 GLU AAA C   1 ? 
ATOM   799  O  O   . GLU A 1 119 ? 9.136   16.546  61.979  1.000 158.584 ? 119 GLU AAA O   1 ? 
ATOM   800  C  CB  . GLU A 1 119 ? 11.350  18.142  63.756  1.000 191.846 ? 119 GLU AAA CB  1 ? 
ATOM   801  C  CG  . GLU A 1 119 ? 12.181  18.455  64.988  1.000 194.322 ? 119 GLU AAA CG  1 ? 
ATOM   802  C  CD  . GLU A 1 119 ? 11.554  19.469  65.930  1.000 198.028 ? 119 GLU AAA CD  1 ? 
ATOM   803  O  OE1 . GLU A 1 119 ? 11.264  20.595  65.473  1.000 194.448 ? 119 GLU AAA OE1 1 ? 
ATOM   804  O  OE2 . GLU A 1 119 ? 11.351  19.130  67.113  1.000 202.332 ? 119 GLU AAA OE2 1 ? 
ATOM   805  N  N   . VAL A 1 120 ? 8.209   18.314  63.054  1.000 158.504 ? 120 VAL AAA N   1 ? 
ATOM   806  C  CA  . VAL A 1 120 ? 6.998   18.414  62.197  1.000 156.329 ? 120 VAL AAA CA  1 ? 
ATOM   807  C  C   . VAL A 1 120 ? 7.382   18.336  60.725  1.000 149.816 ? 120 VAL AAA C   1 ? 
ATOM   808  O  O   . VAL A 1 120 ? 6.894   17.450  59.983  1.000 142.012 ? 120 VAL AAA O   1 ? 
ATOM   809  C  CB  . VAL A 1 120 ? 6.224   19.719  62.482  1.000 163.597 ? 120 VAL AAA CB  1 ? 
ATOM   810  C  CG1 . VAL A 1 120 ? 4.957   19.826  61.643  1.000 166.678 ? 120 VAL AAA CG1 1 ? 
ATOM   811  C  CG2 . VAL A 1 120 ? 5.896   19.886  63.960  1.000 165.091 ? 120 VAL AAA CG2 1 ? 
ATOM   812  N  N   . ASP A 1 121 ? 8.231   19.263  60.317  1.000 149.564 ? 121 ASP AAA N   1 ? 
ATOM   813  C  CA  . ASP A 1 121 ? 8.656   19.346  58.914  1.000 149.820 ? 121 ASP AAA CA  1 ? 
ATOM   814  C  C   . ASP A 1 121 ? 9.157   17.984  58.456  1.000 148.891 ? 121 ASP AAA C   1 ? 
ATOM   815  O  O   . ASP A 1 121 ? 8.907   17.614  57.304  1.000 150.277 ? 121 ASP AAA O   1 ? 
ATOM   816  C  CB  . ASP A 1 121 ? 9.673   20.472  58.710  1.000 150.293 ? 121 ASP AAA CB  1 ? 
ATOM   817  C  CG  . ASP A 1 121 ? 9.030   21.848  58.641  1.000 147.155 ? 121 ASP AAA CG  1 ? 
ATOM   818  O  OD1 . ASP A 1 121 ? 7.983   21.972  57.971  1.000 143.489 ? 121 ASP AAA OD1 1 ? 
ATOM   819  O  OD2 . ASP A 1 121 ? 9.571   22.784  59.264  1.000 143.971 ? 121 ASP AAA OD2 1 ? 
ATOM   820  N  N   . VAL A 1 122 ? 9.790   17.231  59.344  1.000 146.436 ? 122 VAL AAA N   1 ? 
ATOM   821  C  CA  . VAL A 1 122 ? 10.333  15.907  58.972  1.000 147.833 ? 122 VAL AAA CA  1 ? 
ATOM   822  C  C   . VAL A 1 122 ? 9.175   15.011  58.558  1.000 144.850 ? 122 VAL AAA C   1 ? 
ATOM   823  O  O   . VAL A 1 122 ? 9.255   14.340  57.519  1.000 148.305 ? 122 VAL AAA O   1 ? 
ATOM   824  C  CB  . VAL A 1 122 ? 11.158  15.267  60.108  1.000 150.739 ? 122 VAL AAA CB  1 ? 
ATOM   825  C  CG1 . VAL A 1 122 ? 11.752  13.929  59.689  1.000 155.212 ? 122 VAL AAA CG1 1 ? 
ATOM   826  C  CG2 . VAL A 1 122 ? 12.257  16.193  60.609  1.000 151.092 ? 122 VAL AAA CG2 1 ? 
ATOM   827  N  N   . MET A 1 123 ? 8.115   15.010  59.348  1.000 138.221 ? 123 MET AAA N   1 ? 
ATOM   828  C  CA  . MET A 1 123 ? 6.943   14.189  59.006  1.000 135.926 ? 123 MET AAA CA  1 ? 
ATOM   829  C  C   . MET A 1 123 ? 6.334   14.755  57.723  1.000 136.956 ? 123 MET AAA C   1 ? 
ATOM   830  O  O   . MET A 1 123 ? 6.187   14.010  56.746  1.000 136.807 ? 123 MET AAA O   1 ? 
ATOM   831  C  CB  . MET A 1 123 ? 5.919   14.142  60.151  1.000 133.264 ? 123 MET AAA CB  1 ? 
ATOM   832  C  CG  . MET A 1 123 ? 6.434   13.430  61.413  1.000 127.426 ? 123 MET AAA CG  1 ? 
ATOM   833  S  SD  . MET A 1 123 ? 5.138   12.926  62.608  1.000 112.760 ? 123 MET AAA SD  1 ? 
ATOM   834  C  CE  . MET A 1 123 ? 5.369   11.151  62.652  1.000 103.229 ? 123 MET AAA CE  1 ? 
ATOM   835  N  N   . CYS A 1 124 ? 6.069   16.058  57.694  1.000 140.196 ? 124 CYS AAA N   1 ? 
ATOM   836  C  CA  . CYS A 1 124 ? 5.465   16.733  56.508  1.000 146.707 ? 124 CYS AAA CA  1 ? 
ATOM   837  C  C   . CYS A 1 124 ? 6.224   16.495  55.205  1.000 146.647 ? 124 CYS AAA C   1 ? 
ATOM   838  O  O   . CYS A 1 124 ? 5.631   16.619  54.119  1.000 147.315 ? 124 CYS AAA O   1 ? 
ATOM   839  C  CB  . CYS A 1 124 ? 5.344   18.237  56.729  1.000 155.188 ? 124 CYS AAA CB  1 ? 
ATOM   840  S  SG  . CYS A 1 124 ? 3.884   18.703  57.693  1.000 166.878 ? 124 CYS AAA SG  1 ? 
ATOM   841  N  N   . THR A 1 125 ? 7.517   16.235  55.307  1.000 142.437 ? 125 THR AAA N   1 ? 
ATOM   842  C  CA  . THR A 1 125 ? 8.324   15.850  54.139  1.000 133.990 ? 125 THR AAA CA  1 ? 
ATOM   843  C  C   . THR A 1 125 ? 7.910   14.437  53.720  1.000 133.772 ? 125 THR AAA C   1 ? 
ATOM   844  O  O   . THR A 1 125 ? 7.483   14.221  52.568  1.000 125.886 ? 125 THR AAA O   1 ? 
ATOM   845  C  CB  . THR A 1 125 ? 9.824   15.946  54.453  1.000 126.449 ? 125 THR AAA CB  1 ? 
ATOM   846  O  OG1 . THR A 1 125 ? 10.090  17.255  54.959  1.000 116.374 ? 125 THR AAA OG1 1 ? 
ATOM   847  C  CG2 . THR A 1 125 ? 10.703  15.681  53.250  1.000 126.010 ? 125 THR AAA CG2 1 ? 
ATOM   848  N  N   . ALA A 1 126 ? 7.989   13.504  54.664  1.000 140.337 ? 126 ALA AAA N   1 ? 
ATOM   849  C  CA  . ALA A 1 126 ? 7.678   12.074  54.428  1.000 150.391 ? 126 ALA AAA CA  1 ? 
ATOM   850  C  C   . ALA A 1 126 ? 6.242   11.861  53.946  1.000 155.825 ? 126 ALA AAA C   1 ? 
ATOM   851  O  O   . ALA A 1 126 ? 5.986   10.945  53.150  1.000 161.676 ? 126 ALA AAA O   1 ? 
ATOM   852  C  CB  . ALA A 1 126 ? 7.957   11.291  55.688  1.000 155.245 ? 126 ALA AAA CB  1 ? 
ATOM   853  N  N   . PHE A 1 127 ? 5.314   12.659  54.451  1.000 156.686 ? 127 PHE AAA N   1 ? 
ATOM   854  C  CA  . PHE A 1 127 ? 3.882   12.535  54.107  1.000 155.802 ? 127 PHE AAA CA  1 ? 
ATOM   855  C  C   . PHE A 1 127 ? 3.623   12.794  52.630  1.000 155.036 ? 127 PHE AAA C   1 ? 
ATOM   856  O  O   . PHE A 1 127 ? 2.818   12.086  52.018  1.000 156.980 ? 127 PHE AAA O   1 ? 
ATOM   857  C  CB  . PHE A 1 127 ? 3.020   13.482  54.948  1.000 157.468 ? 127 PHE AAA CB  1 ? 
ATOM   858  C  CG  . PHE A 1 127 ? 1.588   13.591  54.484  1.000 157.340 ? 127 PHE AAA CG  1 ? 
ATOM   859  C  CD1 . PHE A 1 127 ? 0.733   12.500  54.556  1.000 153.180 ? 127 PHE AAA CD1 1 ? 
ATOM   860  C  CD2 . PHE A 1 127 ? 1.094   14.779  53.962  1.000 158.559 ? 127 PHE AAA CD2 1 ? 
ATOM   861  C  CE1 . PHE A 1 127 ? -0.581  12.598  54.124  1.000 149.806 ? 127 PHE AAA CE1 1 ? 
ATOM   862  C  CE2 . PHE A 1 127 ? -0.221  14.875  53.531  1.000 153.365 ? 127 PHE AAA CE2 1 ? 
ATOM   863  C  CZ  . PHE A 1 127 ? -1.055  13.784  53.611  1.000 149.505 ? 127 PHE AAA CZ  1 ? 
ATOM   864  N  N   . HIS A 1 128 ? 4.260   13.815  52.078  1.000 151.363 ? 128 HIS AAA N   1 ? 
ATOM   865  C  CA  . HIS A 1 128 ? 4.133   14.129  50.641  1.000 147.187 ? 128 HIS AAA CA  1 ? 
ATOM   866  C  C   . HIS A 1 128 ? 5.037   13.181  49.863  1.000 159.111 ? 128 HIS AAA C   1 ? 
ATOM   867  O  O   . HIS A 1 128 ? 4.586   12.600  48.847  1.000 159.313 ? 128 HIS AAA O   1 ? 
ATOM   868  C  CB  . HIS A 1 128 ? 4.452   15.605  50.356  1.000 136.485 ? 128 HIS AAA CB  1 ? 
ATOM   869  C  CG  . HIS A 1 128 ? 3.489   16.570  50.962  1.000 131.388 ? 128 HIS AAA CG  1 ? 
ATOM   870  N  ND1 . HIS A 1 128 ? 2.141   16.571  50.651  1.000 129.514 ? 128 HIS AAA ND1 1 ? 
ATOM   871  C  CD2 . HIS A 1 128 ? 3.673   17.579  51.841  1.000 128.696 ? 128 HIS AAA CD2 1 ? 
ATOM   872  C  CE1 . HIS A 1 128 ? 1.535   17.528  51.326  1.000 126.707 ? 128 HIS AAA CE1 1 ? 
ATOM   873  N  NE2 . HIS A 1 128 ? 2.455   18.163  52.061  1.000 127.286 ? 128 HIS AAA NE2 1 ? 
ATOM   874  N  N   . ASP A 1 129 ? 6.272   13.008  50.346  1.000 168.910 ? 129 ASP AAA N   1 ? 
ATOM   875  C  CA  . ASP A 1 129 ? 7.251   12.046  49.773  1.000 171.268 ? 129 ASP AAA CA  1 ? 
ATOM   876  C  C   . ASP A 1 129 ? 6.589   10.698  49.471  1.000 173.342 ? 129 ASP AAA C   1 ? 
ATOM   877  O  O   . ASP A 1 129 ? 6.680   10.201  48.330  1.000 174.214 ? 129 ASP AAA O   1 ? 
ATOM   878  C  CB  . ASP A 1 129 ? 8.434   11.874  50.736  1.000 169.221 ? 129 ASP AAA CB  1 ? 
ATOM   879  C  CG  . ASP A 1 129 ? 9.483   10.860  50.308  1.000 170.303 ? 129 ASP AAA CG  1 ? 
ATOM   880  O  OD1 . ASP A 1 129 ? 9.273   9.655   50.557  1.000 165.748 ? 129 ASP AAA OD1 1 ? 
ATOM   881  O  OD2 . ASP A 1 129 ? 10.511  11.285  49.744  1.000 173.998 ? 129 ASP AAA OD2 1 ? 
ATOM   882  N  N   . ASN A 1 130 ? 5.960   10.104  50.482  1.000 171.005 ? 130 ASN AAA N   1 ? 
ATOM   883  C  CA  . ASN A 1 130 ? 5.230   8.823   50.325  1.000 163.452 ? 130 ASN AAA CA  1 ? 
ATOM   884  C  C   . ASN A 1 130 ? 4.026   8.753   51.253  1.000 156.170 ? 130 ASN AAA C   1 ? 
ATOM   885  O  O   . ASN A 1 130 ? 4.135   8.354   52.417  1.000 156.842 ? 130 ASN AAA O   1 ? 
ATOM   886  C  CB  . ASN A 1 130 ? 6.162   7.620   50.512  1.000 163.876 ? 130 ASN AAA CB  1 ? 
ATOM   887  C  CG  . ASN A 1 130 ? 5.633   6.355   49.866  1.000 157.973 ? 130 ASN AAA CG  1 ? 
ATOM   888  O  OD1 . ASN A 1 130 ? 4.424   6.167   49.747  1.000 154.275 ? 130 ASN AAA OD1 1 ? 
ATOM   889  N  ND2 . ASN A 1 130 ? 6.532   5.478   49.450  1.000 153.749 ? 130 ASN AAA ND2 1 ? 
ATOM   890  N  N   . GLU A 1 131 ? 2.882   9.109   50.693  1.000 147.735 ? 131 GLU AAA N   1 ? 
ATOM   891  C  CA  . GLU A 1 131 ? 1.614   9.236   51.430  1.000 147.280 ? 131 GLU AAA CA  1 ? 
ATOM   892  C  C   . GLU A 1 131 ? 1.104   7.874   51.898  1.000 138.184 ? 131 GLU AAA C   1 ? 
ATOM   893  O  O   . GLU A 1 131 ? 0.565   7.772   53.011  1.000 123.565 ? 131 GLU AAA O   1 ? 
ATOM   894  C  CB  . GLU A 1 131 ? 0.587   9.927   50.528  1.000 158.038 ? 131 GLU AAA CB  1 ? 
ATOM   895  C  CG  . GLU A 1 131 ? -0.529  10.625  51.281  1.000 165.168 ? 131 GLU AAA CG  1 ? 
ATOM   896  C  CD  . GLU A 1 131 ? -1.435  11.480  50.410  1.000 168.600 ? 131 GLU AAA CD  1 ? 
ATOM   897  O  OE1 . GLU A 1 131 ? -2.526  11.000  50.041  1.000 169.542 ? 131 GLU AAA OE1 1 ? 
ATOM   898  O  OE2 . GLU A 1 131 ? -1.052  12.630  50.108  1.000 173.726 ? 131 GLU AAA OE2 1 ? 
ATOM   899  N  N   . GLU A 1 132 ? 1.273   6.837   51.089  1.000 142.879 ? 132 GLU AAA N   1 ? 
ATOM   900  C  CA  . GLU A 1 132 ? 0.656   5.523   51.393  1.000 150.855 ? 132 GLU AAA CA  1 ? 
ATOM   901  C  C   . GLU A 1 132 ? 1.448   4.827   52.501  1.000 157.743 ? 132 GLU AAA C   1 ? 
ATOM   902  O  O   . GLU A 1 132 ? 0.889   4.506   53.590  1.000 172.675 ? 132 GLU AAA O   1 ? 
ATOM   903  C  CB  . GLU A 1 132 ? 0.573   4.652   50.133  1.000 147.860 ? 132 GLU AAA CB  1 ? 
ATOM   904  C  CG  . GLU A 1 132 ? 0.186   5.401   48.867  1.000 146.830 ? 132 GLU AAA CG  1 ? 
ATOM   905  C  CD  . GLU A 1 132 ? -0.999  6.345   48.994  1.000 150.359 ? 132 GLU AAA CD  1 ? 
ATOM   906  O  OE1 . GLU A 1 132 ? -1.943  6.020   49.747  1.000 145.442 ? 132 GLU AAA OE1 1 ? 
ATOM   907  O  OE2 . GLU A 1 132 ? -0.975  7.403   48.335  1.000 154.980 ? 132 GLU AAA OE2 1 ? 
ATOM   908  N  N   . THR A 1 133 ? 2.720   4.601   52.209  1.000 154.949 ? 133 THR AAA N   1 ? 
ATOM   909  C  CA  . THR A 1 133 ? 3.720   4.042   53.135  1.000 152.131 ? 133 THR AAA CA  1 ? 
ATOM   910  C  C   . THR A 1 133 ? 3.589   4.763   54.465  1.000 153.605 ? 133 THR AAA C   1 ? 
ATOM   911  O  O   . THR A 1 133 ? 3.647   4.134   55.528  1.000 156.173 ? 133 THR AAA O   1 ? 
ATOM   912  C  CB  . THR A 1 133 ? 5.135   4.200   52.563  1.000 149.828 ? 133 THR AAA CB  1 ? 
ATOM   913  O  OG1 . THR A 1 133 ? 5.206   3.468   51.340  1.000 148.470 ? 133 THR AAA OG1 1 ? 
ATOM   914  C  CG2 . THR A 1 133 ? 6.220   3.726   53.507  1.000 150.733 ? 133 THR AAA CG2 1 ? 
ATOM   915  N  N   . PHE A 1 134 ? 3.364   6.067   54.402  1.000 153.184 ? 134 PHE AAA N   1 ? 
ATOM   916  C  CA  . PHE A 1 134 ? 3.149   6.855   55.623  1.000 155.486 ? 134 PHE AAA CA  1 ? 
ATOM   917  C  C   . PHE A 1 134 ? 1.948   6.381   56.448  1.000 156.268 ? 134 PHE AAA C   1 ? 
ATOM   918  O  O   . PHE A 1 134 ? 2.112   6.213   57.659  1.000 157.414 ? 134 PHE AAA O   1 ? 
ATOM   919  C  CB  . PHE A 1 134 ? 3.017   8.347   55.306  1.000 155.113 ? 134 PHE AAA CB  1 ? 
ATOM   920  C  CG  . PHE A 1 134 ? 3.227   9.247   56.498  1.000 154.392 ? 134 PHE AAA CG  1 ? 
ATOM   921  C  CD1 . PHE A 1 134 ? 4.460   9.308   57.133  1.000 153.913 ? 134 PHE AAA CD1 1 ? 
ATOM   922  C  CD2 . PHE A 1 134 ? 2.195   10.034  56.986  1.000 150.540 ? 134 PHE AAA CD2 1 ? 
ATOM   923  C  CE1 . PHE A 1 134 ? 4.655   10.134  58.230  1.000 152.005 ? 134 PHE AAA CE1 1 ? 
ATOM   924  C  CE2 . PHE A 1 134 ? 2.392   10.859  58.082  1.000 148.942 ? 134 PHE AAA CE2 1 ? 
ATOM   925  C  CZ  . PHE A 1 134 ? 3.621   10.908  58.703  1.000 150.366 ? 134 PHE AAA CZ  1 ? 
ATOM   926  N  N   . LEU A 1 135 ? 0.772   6.171   55.844  1.000 157.615 ? 135 LEU AAA N   1 ? 
ATOM   927  C  CA  . LEU A 1 135 ? -0.448  5.761   56.617  1.000 162.055 ? 135 LEU AAA CA  1 ? 
ATOM   928  C  C   . LEU A 1 135 ? -0.337  4.315   57.112  1.000 158.827 ? 135 LEU AAA C   1 ? 
ATOM   929  O  O   . LEU A 1 135 ? -0.599  3.975   58.316  1.000 164.074 ? 135 LEU AAA O   1 ? 
ATOM   930  C  CB  . LEU A 1 135 ? -1.682  5.897   55.719  1.000 170.532 ? 135 LEU AAA CB  1 ? 
ATOM   931  C  CG  . LEU A 1 135 ? -2.071  7.317   55.314  1.000 180.425 ? 135 LEU AAA CG  1 ? 
ATOM   932  C  CD1 . LEU A 1 135 ? -3.162  7.284   54.253  1.000 184.950 ? 135 LEU AAA CD1 1 ? 
ATOM   933  C  CD2 . LEU A 1 135 ? -2.526  8.126   56.521  1.000 186.086 ? 135 LEU AAA CD2 1 ? 
ATOM   934  N  N   . LYS A 1 136 ? 0.044   3.460   56.178  1.000 156.578 ? 136 LYS AAA N   1 ? 
ATOM   935  C  CA  . LYS A 1 136 ? 0.430   2.084   56.524  1.000 159.464 ? 136 LYS AAA CA  1 ? 
ATOM   936  C  C   . LYS A 1 136 ? 1.390   2.087   57.732  1.000 154.720 ? 136 LYS AAA C   1 ? 
ATOM   937  O  O   . LYS A 1 136 ? 1.210   1.280   58.661  1.000 160.116 ? 136 LYS AAA O   1 ? 
ATOM   938  C  CB  . LYS A 1 136 ? 1.026   1.389   55.296  1.000 164.634 ? 136 LYS AAA CB  1 ? 
ATOM   939  C  CG  . LYS A 1 136 ? 0.030   1.130   54.171  1.000 168.017 ? 136 LYS AAA CG  1 ? 
ATOM   940  C  CD  . LYS A 1 136 ? 0.616   0.379   52.998  1.000 168.463 ? 136 LYS AAA CD  1 ? 
ATOM   941  C  CE  . LYS A 1 136 ? -0.281  0.394   51.778  1.000 167.467 ? 136 LYS AAA CE  1 ? 
ATOM   942  N  NZ  . LYS A 1 136 ? 0.452   -0.031  50.562  1.000 167.283 ? 136 LYS AAA NZ  1 ? 
ATOM   943  N  N   . LYS A 1 137 ? 2.376   2.987   57.743  1.000 148.751 ? 137 LYS AAA N   1 ? 
ATOM   944  C  CA  . LYS A 1 137 ? 3.290   3.157   58.905  1.000 148.980 ? 137 LYS AAA CA  1 ? 
ATOM   945  C  C   . LYS A 1 137 ? 2.506   3.379   60.199  1.000 152.943 ? 137 LYS AAA C   1 ? 
ATOM   946  O  O   . LYS A 1 137 ? 2.810   2.748   61.221  1.000 158.088 ? 137 LYS AAA O   1 ? 
ATOM   947  C  CB  . LYS A 1 137 ? 4.257   4.327   58.684  1.000 146.762 ? 137 LYS AAA CB  1 ? 
ATOM   948  C  CG  . LYS A 1 137 ? 5.584   4.228   59.427  1.000 150.229 ? 137 LYS AAA CG  1 ? 
ATOM   949  C  CD  . LYS A 1 137 ? 6.656   3.465   58.667  1.000 153.549 ? 137 LYS AAA CD  1 ? 
ATOM   950  C  CE  . LYS A 1 137 ? 8.032   3.565   59.295  1.000 152.194 ? 137 LYS AAA CE  1 ? 
ATOM   951  N  NZ  . LYS A 1 137 ? 9.098   3.114   58.368  1.000 146.588 ? 137 LYS AAA NZ  1 ? 
ATOM   952  N  N   . TYR A 1 138 ? 1.507   4.258   60.144  1.000 152.669 ? 138 TYR AAA N   1 ? 
ATOM   953  C  CA  . TYR A 1 138 ? 0.653   4.631   61.309  1.000 147.259 ? 138 TYR AAA CA  1 ? 
ATOM   954  C  C   . TYR A 1 138 ? -0.170  3.442   61.805  1.000 134.081 ? 138 TYR AAA C   1 ? 
ATOM   955  O  O   . TYR A 1 138 ? -0.072  3.026   63.002  1.000 126.501 ? 138 TYR AAA O   1 ? 
ATOM   956  C  CB  . TYR A 1 138 ? -0.246  5.811   60.920  1.000 159.221 ? 138 TYR AAA CB  1 ? 
ATOM   957  C  CG  . TYR A 1 138 ? -1.363  6.164   61.871  1.000 174.640 ? 138 TYR AAA CG  1 ? 
ATOM   958  C  CD1 . TYR A 1 138 ? -1.158  7.052   62.916  1.000 187.089 ? 138 TYR AAA CD1 1 ? 
ATOM   959  C  CD2 . TYR A 1 138 ? -2.645  5.663   61.694  1.000 180.965 ? 138 TYR AAA CD2 1 ? 
ATOM   960  C  CE1 . TYR A 1 138 ? -2.184  7.408   63.778  1.000 196.346 ? 138 TYR AAA CE1 1 ? 
ATOM   961  C  CE2 . TYR A 1 138 ? -3.683  6.008   62.547  1.000 189.451 ? 138 TYR AAA CE2 1 ? 
ATOM   962  C  CZ  . TYR A 1 138 ? -3.452  6.885   63.594  1.000 198.005 ? 138 TYR AAA CZ  1 ? 
ATOM   963  O  OH  . TYR A 1 138 ? -4.460  7.238   64.446  1.000 202.850 ? 138 TYR AAA OH  1 ? 
ATOM   964  N  N   . LEU A 1 139 ? -0.972  2.895   60.890  1.000 126.710 ? 139 LEU AAA N   1 ? 
ATOM   965  C  CA  . LEU A 1 139 ? -1.732  1.667   61.203  1.000 125.756 ? 139 LEU AAA CA  1 ? 
ATOM   966  C  C   . LEU A 1 139 ? -0.785  0.656   61.839  1.000 125.849 ? 139 LEU AAA C   1 ? 
ATOM   967  O  O   . LEU A 1 139 ? -1.078  0.164   62.930  1.000 124.843 ? 139 LEU AAA O   1 ? 
ATOM   968  C  CB  . LEU A 1 139 ? -2.341  1.086   59.922  1.000 128.779 ? 139 LEU AAA CB  1 ? 
ATOM   969  C  CG  . LEU A 1 139 ? -3.571  1.798   59.361  1.000 132.391 ? 139 LEU AAA CG  1 ? 
ATOM   970  C  CD1 . LEU A 1 139 ? -4.045  1.112   58.086  1.000 131.791 ? 139 LEU AAA CD1 1 ? 
ATOM   971  C  CD2 . LEU A 1 139 ? -4.698  1.851   60.382  1.000 135.001 ? 139 LEU AAA CD2 1 ? 
ATOM   972  N  N   . TYR A 1 140 ? 0.332   0.372   61.170  1.000 128.212 ? 140 TYR AAA N   1 ? 
ATOM   973  C  CA  . TYR A 1 140 ? 1.330   -0.595  61.680  1.000 127.224 ? 140 TYR AAA CA  1 ? 
ATOM   974  C  C   . TYR A 1 140 ? 1.765   -0.265  63.092  1.000 125.781 ? 140 TYR AAA C   1 ? 
ATOM   975  O  O   . TYR A 1 140 ? 1.687   -1.129  63.982  1.000 123.568 ? 140 TYR AAA O   1 ? 
ATOM   976  C  CB  . TYR A 1 140 ? 2.556   -0.661  60.764  1.000 129.548 ? 140 TYR AAA CB  1 ? 
ATOM   977  C  CG  . TYR A 1 140 ? 3.739   -1.403  61.338  1.000 131.806 ? 140 TYR AAA CG  1 ? 
ATOM   978  C  CD1 . TYR A 1 140 ? 3.796   -2.788  61.324  1.000 130.179 ? 140 TYR AAA CD1 1 ? 
ATOM   979  C  CD2 . TYR A 1 140 ? 4.808   -0.720  61.896  1.000 135.298 ? 140 TYR AAA CD2 1 ? 
ATOM   980  C  CE1 . TYR A 1 140 ? 4.881   -3.473  61.850  1.000 129.622 ? 140 TYR AAA CE1 1 ? 
ATOM   981  C  CE2 . TYR A 1 140 ? 5.901   -1.389  62.424  1.000 134.668 ? 140 TYR AAA CE2 1 ? 
ATOM   982  C  CZ  . TYR A 1 140 ? 5.939   -2.772  62.400  1.000 131.554 ? 140 TYR AAA CZ  1 ? 
ATOM   983  O  OH  . TYR A 1 140 ? 7.010   -3.444  62.916  1.000 127.510 ? 140 TYR AAA OH  1 ? 
ATOM   984  N  N   . GLU A 1 141 ? 2.229   0.956   63.303  1.000 130.490 ? 141 GLU AAA N   1 ? 
ATOM   985  C  CA  . GLU A 1 141 ? 2.743   1.303   64.640  1.000 137.214 ? 141 GLU AAA CA  1 ? 
ATOM   986  C  C   . GLU A 1 141 ? 1.649   1.204   65.700  1.000 137.360 ? 141 GLU AAA C   1 ? 
ATOM   987  O  O   . GLU A 1 141 ? 1.920   0.616   66.765  1.000 150.891 ? 141 GLU AAA O   1 ? 
ATOM   988  C  CB  . GLU A 1 141 ? 3.412   2.679   64.615  1.000 141.262 ? 141 GLU AAA CB  1 ? 
ATOM   989  C  CG  . GLU A 1 141 ? 4.675   2.732   63.764  1.000 144.036 ? 141 GLU AAA CG  1 ? 
ATOM   990  C  CD  . GLU A 1 141 ? 5.894   1.995   64.298  1.000 147.921 ? 141 GLU AAA CD  1 ? 
ATOM   991  O  OE1 . GLU A 1 141 ? 5.728   1.076   65.127  1.000 147.297 ? 141 GLU AAA OE1 1 ? 
ATOM   992  O  OE2 . GLU A 1 141 ? 7.017   2.346   63.877  1.000 151.079 ? 141 GLU AAA OE2 1 ? 
ATOM   993  N  N   . ILE A 1 142 ? 0.441   1.705   65.438  1.000 125.918 ? 142 ILE AAA N   1 ? 
ATOM   994  C  CA  . ILE A 1 142 ? -0.645  1.529   66.449  1.000 116.283 ? 142 ILE AAA CA  1 ? 
ATOM   995  C  C   . ILE A 1 142 ? -0.966  0.055   66.686  1.000 110.329 ? 142 ILE AAA C   1 ? 
ATOM   996  O  O   . ILE A 1 142 ? -0.985  -0.415  67.849  1.000 105.466 ? 142 ILE AAA O   1 ? 
ATOM   997  C  CB  . ILE A 1 142 ? -1.920  2.303   66.057  1.000 114.954 ? 142 ILE AAA CB  1 ? 
ATOM   998  C  CG1 . ILE A 1 142 ? -1.675  3.812   65.979  1.000 111.568 ? 142 ILE AAA CG1 1 ? 
ATOM   999  C  CG2 . ILE A 1 142 ? -3.062  1.969   67.010  1.000 116.429 ? 142 ILE AAA CG2 1 ? 
ATOM   1000 C  CD1 . ILE A 1 142 ? -1.244  4.444   67.285  1.000 109.523 ? 142 ILE AAA CD1 1 ? 
ATOM   1001 N  N   . ALA A 1 143 ? -1.253  -0.653  65.605  1.000 110.301 ? 143 ALA AAA N   1 ? 
ATOM   1002 C  CA  . ALA A 1 143 ? -1.787  -2.024  65.690  1.000 117.563 ? 143 ALA AAA CA  1 ? 
ATOM   1003 C  C   . ALA A 1 143 ? -0.905  -2.942  66.538  1.000 116.491 ? 143 ALA AAA C   1 ? 
ATOM   1004 O  O   . ALA A 1 143 ? -1.425  -3.701  67.373  1.000 127.689 ? 143 ALA AAA O   1 ? 
ATOM   1005 C  CB  . ALA A 1 143 ? -1.950  -2.581  64.297  1.000 123.328 ? 143 ALA AAA CB  1 ? 
ATOM   1006 N  N   . ARG A 1 144 ? 0.398   -2.906  66.316  1.000 109.573 ? 144 ARG AAA N   1 ? 
ATOM   1007 C  CA  . ARG A 1 144 ? 1.334   -3.729  67.107  1.000 110.006 ? 144 ARG AAA CA  1 ? 
ATOM   1008 C  C   . ARG A 1 144 ? 1.335   -3.349  68.585  1.000 108.654 ? 144 ARG AAA C   1 ? 
ATOM   1009 O  O   . ARG A 1 144 ? 1.642   -4.212  69.429  1.000 107.659 ? 144 ARG AAA O   1 ? 
ATOM   1010 C  CB  . ARG A 1 144 ? 2.745   -3.652  66.517  1.000 113.563 ? 144 ARG AAA CB  1 ? 
ATOM   1011 C  CG  . ARG A 1 144 ? 3.365   -2.264  66.543  1.000 117.879 ? 144 ARG AAA CG  1 ? 
ATOM   1012 C  CD  . ARG A 1 144 ? 4.369   -2.088  65.423  1.000 121.525 ? 144 ARG AAA CD  1 ? 
ATOM   1013 N  NE  . ARG A 1 144 ? 5.503   -2.992  65.554  1.000 122.454 ? 144 ARG AAA NE  1 ? 
ATOM   1014 C  CZ  . ARG A 1 144 ? 6.747   -2.629  65.859  1.000 122.996 ? 144 ARG AAA CZ  1 ? 
ATOM   1015 N  NH1 . ARG A 1 144 ? 7.057   -1.359  66.072  1.000 120.667 ? 144 ARG AAA NH1 1 ? 
ATOM   1016 N  NH2 . ARG A 1 144 ? 7.689   -3.553  65.940  1.000 124.893 ? 144 ARG AAA NH2 1 ? 
ATOM   1017 N  N   . ARG A 1 145 ? 0.974   -2.112  68.900  1.000 106.219 ? 145 ARG AAA N   1 ? 
ATOM   1018 C  CA  . ARG A 1 145 ? 0.942   -1.640  70.306  1.000 103.805 ? 145 ARG AAA CA  1 ? 
ATOM   1019 C  C   . ARG A 1 145 ? -0.423  -1.847  70.948  1.000 102.026 ? 145 ARG AAA C   1 ? 
ATOM   1020 O  O   . ARG A 1 145 ? -0.518  -1.893  72.188  1.000 103.873 ? 145 ARG AAA O   1 ? 
ATOM   1021 C  CB  . ARG A 1 145 ? 1.324   -0.159  70.401  1.000 108.562 ? 145 ARG AAA CB  1 ? 
ATOM   1022 C  CG  . ARG A 1 145 ? 2.809   0.100   70.192  1.000 116.326 ? 145 ARG AAA CG  1 ? 
ATOM   1023 C  CD  . ARG A 1 145 ? 3.196   1.569   70.211  1.000 117.721 ? 145 ARG AAA CD  1 ? 
ATOM   1024 N  NE  . ARG A 1 145 ? 4.625   1.761   69.970  1.000 119.201 ? 145 ARG AAA NE  1 ? 
ATOM   1025 C  CZ  . ARG A 1 145 ? 5.238   1.625   68.791  1.000 118.327 ? 145 ARG AAA CZ  1 ? 
ATOM   1026 N  NH1 . ARG A 1 145 ? 4.560   1.287   67.706  1.000 118.238 ? 145 ARG AAA NH1 1 ? 
ATOM   1027 N  NH2 . ARG A 1 145 ? 6.541   1.829   68.703  1.000 118.460 ? 145 ARG AAA NH2 1 ? 
ATOM   1028 N  N   . HIS A 1 146 ? -1.457  -1.956  70.134  1.000 105.452 ? 146 HIS AAA N   1 ? 
ATOM   1029 C  CA  . HIS A 1 146 ? -2.815  -2.211  70.638  1.000 108.626 ? 146 HIS AAA CA  1 ? 
ATOM   1030 C  C   . HIS A 1 146 ? -3.393  -3.424  69.943  1.000 110.310 ? 146 HIS AAA C   1 ? 
ATOM   1031 O  O   . HIS A 1 146 ? -4.260  -3.317  69.078  1.000 121.282 ? 146 HIS AAA O   1 ? 
ATOM   1032 C  CB  . HIS A 1 146 ? -3.635  -0.922  70.525  1.000 109.360 ? 146 HIS AAA CB  1 ? 
ATOM   1033 C  CG  . HIS A 1 146 ? -3.011  0.209   71.274  1.000 111.950 ? 146 HIS AAA CG  1 ? 
ATOM   1034 N  ND1 . HIS A 1 146 ? -3.182  0.380   72.637  1.000 111.773 ? 146 HIS AAA ND1 1 ? 
ATOM   1035 C  CD2 . HIS A 1 146 ? -2.184  1.197   70.868  1.000 119.246 ? 146 HIS AAA CD2 1 ? 
ATOM   1036 C  CE1 . HIS A 1 146 ? -2.508  1.441   73.033  1.000 115.725 ? 146 HIS AAA CE1 1 ? 
ATOM   1037 N  NE2 . HIS A 1 146 ? -1.886  1.962   71.966  1.000 121.224 ? 146 HIS AAA NE2 1 ? 
ATOM   1038 N  N   . PRO A 1 147 ? -2.898  -4.616  70.309  1.000 102.484 ? 147 PRO AAA N   1 ? 
ATOM   1039 C  CA  . PRO A 1 147 ? -3.254  -5.826  69.592  1.000 100.055 ? 147 PRO AAA CA  1 ? 
ATOM   1040 C  C   . PRO A 1 147 ? -4.734  -6.188  69.676  1.000 94.069  ? 147 PRO AAA C   1 ? 
ATOM   1041 O  O   . PRO A 1 147 ? -5.185  -7.059  68.952  1.000 94.242  ? 147 PRO AAA O   1 ? 
ATOM   1042 C  CB  . PRO A 1 147 ? -2.395  -6.909  70.261  1.000 103.367 ? 147 PRO AAA CB  1 ? 
ATOM   1043 C  CG  . PRO A 1 147 ? -2.107  -6.357  71.636  1.000 104.275 ? 147 PRO AAA CG  1 ? 
ATOM   1044 C  CD  . PRO A 1 147 ? -1.977  -4.865  71.429  1.000 101.880 ? 147 PRO AAA CD  1 ? 
ATOM   1045 N  N   . TYR A 1 148 ? -5.456  -5.530  70.566  1.000 90.272  ? 148 TYR AAA N   1 ? 
ATOM   1046 C  CA  . TYR A 1 148 ? -6.908  -5.708  70.624  1.000 94.688  ? 148 TYR AAA CA  1 ? 
ATOM   1047 C  C   . TYR A 1 148 ? -7.649  -4.455  70.186  1.000 93.096  ? 148 TYR AAA C   1 ? 
ATOM   1048 O  O   . TYR A 1 148 ? -8.809  -4.303  70.555  1.000 96.051  ? 148 TYR AAA O   1 ? 
ATOM   1049 C  CB  . TYR A 1 148 ? -7.307  -6.164  72.031  1.000 98.295  ? 148 TYR AAA CB  1 ? 
ATOM   1050 C  CG  . TYR A 1 148 ? -6.694  -7.473  72.471  1.000 96.215  ? 148 TYR AAA CG  1 ? 
ATOM   1051 C  CD1 . TYR A 1 148 ? -5.559  -7.497  73.265  1.000 96.384  ? 148 TYR AAA CD1 1 ? 
ATOM   1052 C  CD2 . TYR A 1 148 ? -7.249  -8.690  72.105  1.000 92.392  ? 148 TYR AAA CD2 1 ? 
ATOM   1053 C  CE1 . TYR A 1 148 ? -4.991  -8.689  73.683  1.000 94.807  ? 148 TYR AAA CE1 1 ? 
ATOM   1054 C  CE2 . TYR A 1 148 ? -6.692  -9.892  72.512  1.000 91.409  ? 148 TYR AAA CE2 1 ? 
ATOM   1055 C  CZ  . TYR A 1 148 ? -5.558  -9.892  73.306  1.000 93.348  ? 148 TYR AAA CZ  1 ? 
ATOM   1056 O  OH  . TYR A 1 148 ? -4.995  -11.065 73.720  1.000 97.029  ? 148 TYR AAA OH  1 ? 
ATOM   1057 N  N   . PHE A 1 149 ? -7.032  -3.598  69.368  1.000 92.118  ? 149 PHE AAA N   1 ? 
ATOM   1058 C  CA  . PHE A 1 149 ? -7.682  -2.352  68.902  1.000 94.553  ? 149 PHE AAA CA  1 ? 
ATOM   1059 C  C   . PHE A 1 149 ? -8.773  -2.713  67.913  1.000 93.943  ? 149 PHE AAA C   1 ? 
ATOM   1060 O  O   . PHE A 1 149 ? -8.552  -3.558  67.041  1.000 90.989  ? 149 PHE AAA O   1 ? 
ATOM   1061 C  CB  . PHE A 1 149 ? -6.711  -1.383  68.221  1.000 97.498  ? 149 PHE AAA CB  1 ? 
ATOM   1062 C  CG  . PHE A 1 149 ? -7.236  0.025   68.045  1.000 96.087  ? 149 PHE AAA CG  1 ? 
ATOM   1063 C  CD1 . PHE A 1 149 ? -8.245  0.318   67.137  1.000 92.751  ? 149 PHE AAA CD1 1 ? 
ATOM   1064 C  CD2 . PHE A 1 149 ? -6.702  1.070   68.782  1.000 97.136  ? 149 PHE AAA CD2 1 ? 
ATOM   1065 C  CE1 . PHE A 1 149 ? -8.710  1.615   66.979  1.000 90.131  ? 149 PHE AAA CE1 1 ? 
ATOM   1066 C  CE2 . PHE A 1 149 ? -7.166  2.366   68.623  1.000 95.813  ? 149 PHE AAA CE2 1 ? 
ATOM   1067 C  CZ  . PHE A 1 149 ? -8.169  2.637   67.722  1.000 93.647  ? 149 PHE AAA CZ  1 ? 
ATOM   1068 N  N   . TYR A 1 150 ? -9.904  -2.020  68.012  1.000 91.371  ? 150 TYR AAA N   1 ? 
ATOM   1069 C  CA  . TYR A 1 150 ? -11.102 -2.281  67.176  1.000 88.022  ? 150 TYR AAA CA  1 ? 
ATOM   1070 C  C   . TYR A 1 150 ? -10.852 -1.940  65.707  1.000 88.288  ? 150 TYR AAA C   1 ? 
ATOM   1071 O  O   . TYR A 1 150 ? -11.054 -0.798  65.282  1.000 97.404  ? 150 TYR AAA O   1 ? 
ATOM   1072 C  CB  . TYR A 1 150 ? -12.287 -1.485  67.731  1.000 86.126  ? 150 TYR AAA CB  1 ? 
ATOM   1073 C  CG  . TYR A 1 150 ? -13.647 -1.867  67.203  1.000 87.227  ? 150 TYR AAA CG  1 ? 
ATOM   1074 C  CD1 . TYR A 1 150 ? -13.845 -2.998  66.424  1.000 86.705  ? 150 TYR AAA CD1 1 ? 
ATOM   1075 C  CD2 . TYR A 1 150 ? -14.762 -1.112  67.534  1.000 90.861  ? 150 TYR AAA CD2 1 ? 
ATOM   1076 C  CE1 . TYR A 1 150 ? -15.104 -3.347  65.959  1.000 87.714  ? 150 TYR AAA CE1 1 ? 
ATOM   1077 C  CE2 . TYR A 1 150 ? -16.029 -1.448  67.082  1.000 93.790  ? 150 TYR AAA CE2 1 ? 
ATOM   1078 C  CZ  . TYR A 1 150 ? -16.202 -2.572  66.289  1.000 91.529  ? 150 TYR AAA CZ  1 ? 
ATOM   1079 O  OH  . TYR A 1 150 ? -17.439 -2.925  65.829  1.000 88.076  ? 150 TYR AAA OH  1 ? 
ATOM   1080 N  N   . ALA A 1 151 ? -10.492 -2.950  64.919  1.000 85.285  ? 151 ALA AAA N   1 ? 
ATOM   1081 C  CA  . ALA A 1 151 ? -9.939  -2.739  63.559  1.000 86.797  ? 151 ALA AAA CA  1 ? 
ATOM   1082 C  C   . ALA A 1 151 ? -10.719 -1.707  62.729  1.000 91.864  ? 151 ALA AAA C   1 ? 
ATOM   1083 O  O   . ALA A 1 151 ? -10.146 -0.673  62.327  1.000 93.086  ? 151 ALA AAA O   1 ? 
ATOM   1084 C  CB  . ALA A 1 151 ? -9.821  -4.060  62.842  1.000 84.891  ? 151 ALA AAA CB  1 ? 
ATOM   1085 N  N   . PRO A 1 152 ? -12.024 -1.941  62.440  1.000 97.579  ? 152 PRO AAA N   1 ? 
ATOM   1086 C  CA  . PRO A 1 152 ? -12.834 -0.924  61.772  1.000 98.560  ? 152 PRO AAA CA  1 ? 
ATOM   1087 C  C   . PRO A 1 152 ? -12.514 0.502   62.246  1.000 97.707  ? 152 PRO AAA C   1 ? 
ATOM   1088 O  O   . PRO A 1 152 ? -12.118 1.338   61.428  1.000 95.900  ? 152 PRO AAA O   1 ? 
ATOM   1089 C  CB  . PRO A 1 152 ? -14.269 -1.314  62.160  1.000 99.004  ? 152 PRO AAA CB  1 ? 
ATOM   1090 C  CG  . PRO A 1 152 ? -14.215 -2.820  62.315  1.000 99.370  ? 152 PRO AAA CG  1 ? 
ATOM   1091 C  CD  . PRO A 1 152 ? -12.811 -3.134  62.796  1.000 99.497  ? 152 PRO AAA CD  1 ? 
ATOM   1092 N  N   . GLU A 1 153 ? -12.628 0.753   63.553  1.000 98.317  ? 153 GLU AAA N   1 ? 
ATOM   1093 C  CA  . GLU A 1 153 ? -12.388 2.105   64.105  1.000 97.756  ? 153 GLU AAA CA  1 ? 
ATOM   1094 C  C   . GLU A 1 153 ? -11.001 2.584   63.755  1.000 92.789  ? 153 GLU AAA C   1 ? 
ATOM   1095 O  O   . GLU A 1 153 ? -10.840 3.751   63.402  1.000 97.303  ? 153 GLU AAA O   1 ? 
ATOM   1096 C  CB  . GLU A 1 153 ? -12.571 2.145   65.625  1.000 102.065 ? 153 GLU AAA CB  1 ? 
ATOM   1097 C  CG  . GLU A 1 153 ? -14.024 2.246   66.069  1.000 105.538 ? 153 GLU AAA CG  1 ? 
ATOM   1098 C  CD  . GLU A 1 153 ? -14.589 3.650   66.254  1.000 104.025 ? 153 GLU AAA CD  1 ? 
ATOM   1099 O  OE1 . GLU A 1 153 ? -13.887 4.516   66.828  1.000 99.806  ? 153 GLU AAA OE1 1 ? 
ATOM   1100 O  OE2 . GLU A 1 153 ? -15.745 3.869   65.839  1.000 101.491 ? 153 GLU AAA OE2 1 ? 
ATOM   1101 N  N   . LEU A 1 154 ? -10.036 1.693   63.834  1.000 84.668  ? 154 LEU AAA N   1 ? 
ATOM   1102 C  CA  . LEU A 1 154 ? -8.670  2.070   63.511  1.000 79.028  ? 154 LEU AAA CA  1 ? 
ATOM   1103 C  C   . LEU A 1 154 ? -8.609  2.675   62.111  1.000 83.233  ? 154 LEU AAA C   1 ? 
ATOM   1104 O  O   . LEU A 1 154 ? -7.795  3.584   61.868  1.000 87.846  ? 154 LEU AAA O   1 ? 
ATOM   1105 C  CB  . LEU A 1 154 ? -7.736  0.866   63.628  1.000 74.212  ? 154 LEU AAA CB  1 ? 
ATOM   1106 C  CG  . LEU A 1 154 ? -6.251  1.211   63.574  1.000 72.773  ? 154 LEU AAA CG  1 ? 
ATOM   1107 C  CD1 . LEU A 1 154 ? -5.905  2.297   64.579  1.000 73.144  ? 154 LEU AAA CD1 1 ? 
ATOM   1108 C  CD2 . LEU A 1 154 ? -5.400  -0.022  63.814  1.000 73.390  ? 154 LEU AAA CD2 1 ? 
ATOM   1109 N  N   . LEU A 1 155 ? -9.472  2.219   61.211  1.000 87.571  ? 155 LEU AAA N   1 ? 
ATOM   1110 C  CA  . LEU A 1 155 ? -9.604  2.876   59.884  1.000 92.175  ? 155 LEU AAA CA  1 ? 
ATOM   1111 C  C   . LEU A 1 155 ? -10.084 4.322   60.022  1.000 93.537  ? 155 LEU AAA C   1 ? 
ATOM   1112 O  O   . LEU A 1 155 ? -9.444  5.259   59.489  1.000 94.683  ? 155 LEU AAA O   1 ? 
ATOM   1113 C  CB  . LEU A 1 155 ? -10.566 2.089   58.989  1.000 93.490  ? 155 LEU AAA CB  1 ? 
ATOM   1114 C  CG  . LEU A 1 155 ? -10.180 0.640   58.702  1.000 97.308  ? 155 LEU AAA CG  1 ? 
ATOM   1115 C  CD1 . LEU A 1 155 ? -11.074 0.061   57.617  1.000 98.531  ? 155 LEU AAA CD1 1 ? 
ATOM   1116 C  CD2 . LEU A 1 155 ? -8.713  0.523   58.303  1.000 98.769  ? 155 LEU AAA CD2 1 ? 
ATOM   1117 N  N   . PHE A 1 156 ? -11.188 4.511   60.729  1.000 96.995  ? 156 PHE AAA N   1 ? 
ATOM   1118 C  CA  . PHE A 1 156 ? -11.701 5.866   61.014  1.000 105.079 ? 156 PHE AAA CA  1 ? 
ATOM   1119 C  C   . PHE A 1 156 ? -10.538 6.715   61.490  1.000 102.566 ? 156 PHE AAA C   1 ? 
ATOM   1120 O  O   . PHE A 1 156 ? -10.259 7.785   60.947  1.000 104.072 ? 156 PHE AAA O   1 ? 
ATOM   1121 C  CB  . PHE A 1 156 ? -12.845 5.824   62.031  1.000 117.453 ? 156 PHE AAA CB  1 ? 
ATOM   1122 C  CG  . PHE A 1 156 ? -13.457 7.169   62.337  1.000 129.553 ? 156 PHE AAA CG  1 ? 
ATOM   1123 C  CD1 . PHE A 1 156 ? -14.061 7.914   61.336  1.000 135.647 ? 156 PHE AAA CD1 1 ? 
ATOM   1124 C  CD2 . PHE A 1 156 ? -13.427 7.693   63.622  1.000 136.832 ? 156 PHE AAA CD2 1 ? 
ATOM   1125 C  CE1 . PHE A 1 156 ? -14.619 9.153   61.611  1.000 141.114 ? 156 PHE AAA CE1 1 ? 
ATOM   1126 C  CE2 . PHE A 1 156 ? -13.987 8.932   63.896  1.000 142.846 ? 156 PHE AAA CE2 1 ? 
ATOM   1127 C  CZ  . PHE A 1 156 ? -14.582 9.661   62.890  1.000 144.102 ? 156 PHE AAA CZ  1 ? 
ATOM   1128 N  N   . PHE A 1 157 ? -9.864  6.216   62.502  1.000 99.268  ? 157 PHE AAA N   1 ? 
ATOM   1129 C  CA  . PHE A 1 157 ? -8.690  6.900   63.045  1.000 96.800  ? 157 PHE AAA CA  1 ? 
ATOM   1130 C  C   . PHE A 1 157 ? -7.681  7.210   61.945  1.000 96.211  ? 157 PHE AAA C   1 ? 
ATOM   1131 O  O   . PHE A 1 157 ? -7.185  8.337   61.876  1.000 96.761  ? 157 PHE AAA O   1 ? 
ATOM   1132 C  CB  . PHE A 1 157 ? -8.058  6.090   64.180  1.000 97.981  ? 157 PHE AAA CB  1 ? 
ATOM   1133 C  CG  . PHE A 1 157 ? -8.775  6.239   65.496  1.000 102.554 ? 157 PHE AAA CG  1 ? 
ATOM   1134 C  CD1 . PHE A 1 157 ? -9.805  5.379   65.845  1.000 110.500 ? 157 PHE AAA CD1 1 ? 
ATOM   1135 C  CD2 . PHE A 1 157 ? -8.442  7.258   66.373  1.000 103.807 ? 157 PHE AAA CD2 1 ? 
ATOM   1136 C  CE1 . PHE A 1 157 ? -10.478 5.524   67.049  1.000 114.900 ? 157 PHE AAA CE1 1 ? 
ATOM   1137 C  CE2 . PHE A 1 157 ? -9.114  7.400   67.578  1.000 110.372 ? 157 PHE AAA CE2 1 ? 
ATOM   1138 C  CZ  . PHE A 1 157 ? -10.130 6.534   67.915  1.000 113.920 ? 157 PHE AAA CZ  1 ? 
ATOM   1139 N  N   . ALA A 1 158 ? -7.379  6.245   61.085  1.000 97.733  ? 158 ALA AAA N   1 ? 
ATOM   1140 C  CA  . ALA A 1 158 ? -6.395  6.475   60.005  1.000 101.245 ? 158 ALA AAA CA  1 ? 
ATOM   1141 C  C   . ALA A 1 158 ? -6.844  7.572   59.033  1.000 104.045 ? 158 ALA AAA C   1 ? 
ATOM   1142 O  O   . ALA A 1 158 ? -6.026  8.411   58.629  1.000 108.207 ? 158 ALA AAA O   1 ? 
ATOM   1143 C  CB  . ALA A 1 158 ? -6.126  5.184   59.275  1.000 101.555 ? 158 ALA AAA CB  1 ? 
ATOM   1144 N  N   . LYS A 1 159 ? -8.118  7.589   58.653  1.000 104.829 ? 159 LYS AAA N   1 ? 
ATOM   1145 C  CA  . LYS A 1 159 ? -8.599  8.629   57.710  1.000 105.342 ? 159 LYS AAA CA  1 ? 
ATOM   1146 C  C   . LYS A 1 159 ? -8.450  10.014  58.335  1.000 103.726 ? 159 LYS AAA C   1 ? 
ATOM   1147 O  O   . LYS A 1 159 ? -7.929  10.950  57.692  1.000 106.802 ? 159 LYS AAA O   1 ? 
ATOM   1148 C  CB  . LYS A 1 159 ? -10.054 8.380   57.301  1.000 108.766 ? 159 LYS AAA CB  1 ? 
ATOM   1149 C  CG  . LYS A 1 159 ? -10.553 9.274   56.174  1.000 112.352 ? 159 LYS AAA CG  1 ? 
ATOM   1150 C  CD  . LYS A 1 159 ? -11.879 8.855   55.586  1.000 117.004 ? 159 LYS AAA CD  1 ? 
ATOM   1151 C  CE  . LYS A 1 159 ? -12.274 9.708   54.399  1.000 123.224 ? 159 LYS AAA CE  1 ? 
ATOM   1152 N  NZ  . LYS A 1 159 ? -13.642 9.391   53.925  1.000 129.263 ? 159 LYS AAA NZ  1 ? 
ATOM   1153 N  N   . ARG A 1 160 ? -8.900  10.120  59.577  1.000 102.532 ? 160 ARG AAA N   1 ? 
ATOM   1154 C  CA  . ARG A 1 160 ? -8.768  11.360  60.361  1.000 108.544 ? 160 ARG AAA CA  1 ? 
ATOM   1155 C  C   . ARG A 1 160 ? -7.304  11.706  60.616  1.000 115.274 ? 160 ARG AAA C   1 ? 
ATOM   1156 O  O   . ARG A 1 160 ? -6.996  12.887  60.816  1.000 126.186 ? 160 ARG AAA O   1 ? 
ATOM   1157 C  CB  . ARG A 1 160 ? -9.537  11.252  61.680  1.000 109.705 ? 160 ARG AAA CB  1 ? 
ATOM   1158 C  CG  . ARG A 1 160 ? -11.017 11.592  61.567  1.000 112.338 ? 160 ARG AAA CG  1 ? 
ATOM   1159 C  CD  . ARG A 1 160 ? -11.627 11.841  62.934  1.000 116.446 ? 160 ARG AAA CD  1 ? 
ATOM   1160 N  NE  . ARG A 1 160 ? -11.387 10.712  63.828  1.000 118.607 ? 160 ARG AAA NE  1 ? 
ATOM   1161 C  CZ  . ARG A 1 160 ? -11.356 10.765  65.159  1.000 118.242 ? 160 ARG AAA CZ  1 ? 
ATOM   1162 N  NH1 . ARG A 1 160 ? -11.546 11.907  65.802  1.000 119.794 ? 160 ARG AAA NH1 1 ? 
ATOM   1163 N  NH2 . ARG A 1 160 ? -11.124 9.659   65.846  1.000 115.972 ? 160 ARG AAA NH2 1 ? 
ATOM   1164 N  N   . TYR A 1 161 ? -6.426  10.708  60.596  1.000 120.449 ? 161 TYR AAA N   1 ? 
ATOM   1165 C  CA  . TYR A 1 161 ? -4.965  10.919  60.673  1.000 130.001 ? 161 TYR AAA CA  1 ? 
ATOM   1166 C  C   . TYR A 1 161 ? -4.411  11.421  59.342  1.000 135.234 ? 161 TYR AAA C   1 ? 
ATOM   1167 O  O   . TYR A 1 161 ? -3.462  12.210  59.328  1.000 139.048 ? 161 TYR AAA O   1 ? 
ATOM   1168 C  CB  . TYR A 1 161 ? -4.275  9.631   61.134  1.000 139.241 ? 161 TYR AAA CB  1 ? 
ATOM   1169 C  CG  . TYR A 1 161 ? -2.775  9.717   61.272  1.000 151.882 ? 161 TYR AAA CG  1 ? 
ATOM   1170 C  CD1 . TYR A 1 161 ? -2.187  10.325  62.371  1.000 159.129 ? 161 TYR AAA CD1 1 ? 
ATOM   1171 C  CD2 . TYR A 1 161 ? -1.937  9.173   60.312  1.000 158.477 ? 161 TYR AAA CD2 1 ? 
ATOM   1172 C  CE1 . TYR A 1 161 ? -0.809  10.396  62.508  1.000 162.396 ? 161 TYR AAA CE1 1 ? 
ATOM   1173 C  CE2 . TYR A 1 161 ? -0.557  9.238   60.432  1.000 161.077 ? 161 TYR AAA CE2 1 ? 
ATOM   1174 C  CZ  . TYR A 1 161 ? 0.011   9.854   61.534  1.000 161.084 ? 161 TYR AAA CZ  1 ? 
ATOM   1175 O  OH  . TYR A 1 161 ? 1.367   9.929   61.672  1.000 160.592 ? 161 TYR AAA OH  1 ? 
ATOM   1176 N  N   . LYS A 1 162 ? -4.981  10.978  58.232  1.000 143.056 ? 162 LYS AAA N   1 ? 
ATOM   1177 C  CA  . LYS A 1 162 ? -4.617  11.520  56.903  1.000 151.365 ? 162 LYS AAA CA  1 ? 
ATOM   1178 C  C   . LYS A 1 162 ? -5.068  12.985  56.798  1.000 155.333 ? 162 LYS AAA C   1 ? 
ATOM   1179 O  O   . LYS A 1 162 ? -4.249  13.882  56.474  1.000 174.986 ? 162 LYS AAA O   1 ? 
ATOM   1180 C  CB  . LYS A 1 162 ? -5.288  10.673  55.814  1.000 157.017 ? 162 LYS AAA CB  1 ? 
ATOM   1181 C  CG  . LYS A 1 162 ? -4.982  11.064  54.374  1.000 165.351 ? 162 LYS AAA CG  1 ? 
ATOM   1182 C  CD  . LYS A 1 162 ? -5.697  10.192  53.360  1.000 177.031 ? 162 LYS AAA CD  1 ? 
ATOM   1183 C  CE  . LYS A 1 162 ? -5.124  10.305  51.963  1.000 187.634 ? 162 LYS AAA CE  1 ? 
ATOM   1184 N  NZ  . LYS A 1 162 ? -5.762  9.347   51.028  1.000 195.721 ? 162 LYS AAA NZ  1 ? 
ATOM   1185 N  N   . ALA A 1 163 ? -6.354  13.201  57.084  1.000 147.591 ? 163 ALA AAA N   1 ? 
ATOM   1186 C  CA  . ALA A 1 163 ? -7.038  14.524  57.013  1.000 140.242 ? 163 ALA AAA CA  1 ? 
ATOM   1187 C  C   . ALA A 1 163 ? -6.288  15.678  57.697  1.000 138.220 ? 163 ALA AAA C   1 ? 
ATOM   1188 O  O   . ALA A 1 163 ? -6.530  16.876  57.369  1.000 146.396 ? 163 ALA AAA O   1 ? 
ATOM   1189 C  CB  . ALA A 1 163 ? -8.431  14.398  57.581  1.000 138.340 ? 163 ALA AAA CB  1 ? 
ATOM   1190 N  N   . ALA A 1 164 ? -5.433  15.357  58.657  1.000 131.566 ? 164 ALA AAA N   1 ? 
ATOM   1191 C  CA  . ALA A 1 164 ? -4.666  16.352  59.412  1.000 123.079 ? 164 ALA AAA CA  1 ? 
ATOM   1192 C  C   . ALA A 1 164 ? -3.357  16.649  58.712  1.000 118.963 ? 164 ALA AAA C   1 ? 
ATOM   1193 O  O   . ALA A 1 164 ? -2.865  17.783  58.772  1.000 119.057 ? 164 ALA AAA O   1 ? 
ATOM   1194 C  CB  . ALA A 1 164 ? -4.430  15.866  60.822  1.000 123.313 ? 164 ALA AAA CB  1 ? 
ATOM   1195 N  N   . PHE A 1 165 ? -2.780  15.631  58.094  1.000 114.554 ? 165 PHE AAA N   1 ? 
ATOM   1196 C  CA  . PHE A 1 165 ? -1.534  15.795  57.328  1.000 111.033 ? 165 PHE AAA CA  1 ? 
ATOM   1197 C  C   . PHE A 1 165 ? -1.847  16.501  56.017  1.000 112.265 ? 165 PHE AAA C   1 ? 
ATOM   1198 O  O   . PHE A 1 165 ? -1.099  17.390  55.601  1.000 108.444 ? 165 PHE AAA O   1 ? 
ATOM   1199 C  CB  . PHE A 1 165 ? -0.837  14.443  57.142  1.000 108.200 ? 165 PHE AAA CB  1 ? 
ATOM   1200 C  CG  . PHE A 1 165 ? -0.016  14.009  58.332  1.000 108.849 ? 165 PHE AAA CG  1 ? 
ATOM   1201 C  CD1 . PHE A 1 165 ? 1.362   14.163  58.338  1.000 113.694 ? 165 PHE AAA CD1 1 ? 
ATOM   1202 C  CD2 . PHE A 1 165 ? -0.619  13.478  59.461  1.000 105.926 ? 165 PHE AAA CD2 1 ? 
ATOM   1203 C  CE1 . PHE A 1 165 ? 2.115   13.784  59.440  1.000 112.966 ? 165 PHE AAA CE1 1 ? 
ATOM   1204 C  CE2 . PHE A 1 165 ? 0.136   13.096  60.561  1.000 105.216 ? 165 PHE AAA CE2 1 ? 
ATOM   1205 C  CZ  . PHE A 1 165 ? 1.503   13.247  60.548  1.000 108.146 ? 165 PHE AAA CZ  1 ? 
ATOM   1206 N  N   . THR A 1 166 ? -2.963  16.130  55.392  1.000 119.471 ? 166 THR AAA N   1 ? 
ATOM   1207 C  CA  . THR A 1 166 ? -3.458  16.871  54.210  1.000 127.254 ? 166 THR AAA CA  1 ? 
ATOM   1208 C  C   . THR A 1 166 ? -3.494  18.380  54.489  1.000 132.695 ? 166 THR AAA C   1 ? 
ATOM   1209 O  O   . THR A 1 166 ? -2.713  19.143  53.891  1.000 135.082 ? 166 THR AAA O   1 ? 
ATOM   1210 C  CB  . THR A 1 166 ? -4.849  16.411  53.743  1.000 128.633 ? 166 THR AAA CB  1 ? 
ATOM   1211 O  OG1 . THR A 1 166 ? -4.968  14.999  53.906  1.000 137.499 ? 166 THR AAA OG1 1 ? 
ATOM   1212 C  CG2 . THR A 1 166 ? -5.122  16.765  52.297  1.000 127.906 ? 166 THR AAA CG2 1 ? 
ATOM   1213 N  N   . GLU A 1 167 ? -4.367  18.811  55.396  1.000 138.860 ? 167 GLU AAA N   1 ? 
ATOM   1214 C  CA  . GLU A 1 167 ? -4.445  20.232  55.843  1.000 144.989 ? 167 GLU AAA CA  1 ? 
ATOM   1215 C  C   . GLU A 1 167 ? -3.115  20.743  56.417  1.000 153.704 ? 167 GLU AAA C   1 ? 
ATOM   1216 O  O   . GLU A 1 167 ? -2.427  21.531  55.761  1.000 160.775 ? 167 GLU AAA O   1 ? 
ATOM   1217 C  CB  . GLU A 1 167 ? -5.555  20.390  56.885  1.000 142.669 ? 167 GLU AAA CB  1 ? 
ATOM   1218 N  N   . CYS A 1 168 ? -2.751  20.339  57.629  1.000 158.602 ? 168 CYS AAA N   1 ? 
ATOM   1219 C  CA  . CYS A 1 168 ? -1.657  21.012  58.366  1.000 157.097 ? 168 CYS AAA CA  1 ? 
ATOM   1220 C  C   . CYS A 1 168 ? -0.289  20.963  57.677  1.000 158.320 ? 168 CYS AAA C   1 ? 
ATOM   1221 O  O   . CYS A 1 168 ? 0.527   21.857  57.987  1.000 152.558 ? 168 CYS AAA O   1 ? 
ATOM   1222 C  CB  . CYS A 1 168 ? -1.554  20.484  59.791  1.000 157.835 ? 168 CYS AAA CB  1 ? 
ATOM   1223 S  SG  . CYS A 1 168 ? -3.109  20.601  60.719  1.000 165.655 ? 168 CYS AAA SG  1 ? 
ATOM   1224 N  N   . CYS A 1 169 ? -0.001  20.010  56.789  1.000 166.098 ? 169 CYS AAA N   1 ? 
ATOM   1225 C  CA  . CYS A 1 169 ? 1.252   20.118  56.006  1.000 176.044 ? 169 CYS AAA CA  1 ? 
ATOM   1226 C  C   . CYS A 1 169 ? 1.040   21.056  54.835  1.000 183.285 ? 169 CYS AAA C   1 ? 
ATOM   1227 O  O   . CYS A 1 169 ? 1.586   20.818  53.737  1.000 191.605 ? 169 CYS AAA O   1 ? 
ATOM   1228 C  CB  . CYS A 1 169 ? 1.743   18.762  55.508  1.000 175.022 ? 169 CYS AAA CB  1 ? 
ATOM   1229 S  SG  . CYS A 1 169 ? 2.348   17.679  56.828  1.000 173.317 ? 169 CYS AAA SG  1 ? 
ATOM   1230 N  N   . GLN A 1 170 ? 0.230   22.075  55.078  1.000 183.058 ? 170 GLN AAA N   1 ? 
ATOM   1231 C  CA  . GLN A 1 170 ? -0.220  23.007  54.039  1.000 183.529 ? 170 GLN AAA CA  1 ? 
ATOM   1232 C  C   . GLN A 1 170 ? -0.865  24.231  54.688  1.000 194.536 ? 170 GLN AAA C   1 ? 
ATOM   1233 O  O   . GLN A 1 170 ? -2.041  24.522  54.420  1.000 197.797 ? 170 GLN AAA O   1 ? 
ATOM   1234 C  CB  . GLN A 1 170 ? -1.185  22.317  53.067  1.000 175.341 ? 170 GLN AAA CB  1 ? 
ATOM   1235 C  CG  . GLN A 1 170 ? -1.317  23.030  51.728  1.000 168.564 ? 170 GLN AAA CG  1 ? 
ATOM   1236 C  CD  . GLN A 1 170 ? -2.337  22.388  50.819  1.000 165.338 ? 170 GLN AAA CD  1 ? 
ATOM   1237 O  OE1 . GLN A 1 170 ? -3.081  21.495  51.216  1.000 166.525 ? 170 GLN AAA OE1 1 ? 
ATOM   1238 N  NE2 . GLN A 1 170 ? -2.387  22.851  49.580  1.000 160.818 ? 170 GLN AAA NE2 1 ? 
ATOM   1239 N  N   . ALA A 1 171 ? -0.090  24.914  55.516  1.000 202.411 ? 171 ALA AAA N   1 ? 
ATOM   1240 C  CA  . ALA A 1 171 ? -0.516  26.120  56.243  1.000 208.076 ? 171 ALA AAA CA  1 ? 
ATOM   1241 C  C   . ALA A 1 171 ? 0.710   26.889  56.716  1.000 211.972 ? 171 ALA AAA C   1 ? 
ATOM   1242 O  O   . ALA A 1 171 ? 1.860   26.419  56.539  1.000 212.265 ? 171 ALA AAA O   1 ? 
ATOM   1243 C  CB  . ALA A 1 171 ? -1.408  25.735  57.399  1.000 206.601 ? 171 ALA AAA CB  1 ? 
ATOM   1244 N  N   . ALA A 1 172 ? 0.475   28.058  57.298  1.000 212.764 ? 172 ALA AAA N   1 ? 
ATOM   1245 C  CA  . ALA A 1 172 ? 1.552   28.908  57.825  1.000 211.722 ? 172 ALA AAA CA  1 ? 
ATOM   1246 C  C   . ALA A 1 172 ? 2.270   28.145  58.917  1.000 213.784 ? 172 ALA AAA C   1 ? 
ATOM   1247 O  O   . ALA A 1 172 ? 3.410   27.700  58.714  1.000 210.004 ? 172 ALA AAA O   1 ? 
ATOM   1248 C  CB  . ALA A 1 172 ? 0.999   30.230  58.309  1.000 208.595 ? 172 ALA AAA CB  1 ? 
ATOM   1249 N  N   . ASP A 1 173 ? 1.583   27.962  60.025  1.000 219.461 ? 173 ASP AAA N   1 ? 
ATOM   1250 C  CA  . ASP A 1 173 ? 2.139   27.150  61.114  1.000 217.217 ? 173 ASP AAA CA  1 ? 
ATOM   1251 C  C   . ASP A 1 173 ? 1.621   25.741  60.937  1.000 211.506 ? 173 ASP AAA C   1 ? 
ATOM   1252 O  O   . ASP A 1 173 ? 0.398   25.523  60.923  1.000 223.731 ? 173 ASP AAA O   1 ? 
ATOM   1253 C  CB  . ASP A 1 173 ? 1.807   27.721  62.496  1.000 223.082 ? 173 ASP AAA CB  1 ? 
ATOM   1254 C  CG  . ASP A 1 173 ? 2.776   27.284  63.585  1.000 226.843 ? 173 ASP AAA CG  1 ? 
ATOM   1255 O  OD1 . ASP A 1 173 ? 3.662   26.449  63.294  1.000 214.135 ? 173 ASP AAA OD1 1 ? 
ATOM   1256 O  OD2 . ASP A 1 173 ? 2.643   27.786  64.719  1.000 242.670 ? 173 ASP AAA OD2 1 ? 
ATOM   1257 N  N   . LYS A 1 174 ? 2.556   24.820  60.824  1.000 190.600 ? 174 LYS AAA N   1 ? 
ATOM   1258 C  CA  . LYS A 1 174 ? 2.246   23.393  60.776  1.000 174.961 ? 174 LYS AAA CA  1 ? 
ATOM   1259 C  C   . LYS A 1 174 ? 2.113   22.954  62.221  1.000 171.707 ? 174 LYS AAA C   1 ? 
ATOM   1260 O  O   . LYS A 1 174 ? 1.081   22.451  62.598  1.000 182.699 ? 174 LYS AAA O   1 ? 
ATOM   1261 C  CB  . LYS A 1 174 ? 3.336   22.651  59.996  1.000 163.424 ? 174 LYS AAA CB  1 ? 
ATOM   1262 C  CG  . LYS A 1 174 ? 3.608   23.214  58.607  1.000 159.700 ? 174 LYS AAA CG  1 ? 
ATOM   1263 C  CD  . LYS A 1 174 ? 4.642   22.447  57.822  1.000 159.126 ? 174 LYS AAA CD  1 ? 
ATOM   1264 C  CE  . LYS A 1 174 ? 4.710   22.874  56.371  1.000 161.311 ? 174 LYS AAA CE  1 ? 
ATOM   1265 N  NZ  . LYS A 1 174 ? 5.819   22.203  55.654  1.000 161.388 ? 174 LYS AAA NZ  1 ? 
ATOM   1266 N  N   . ALA A 1 175 ? 3.132   23.192  63.037  1.000 160.110 ? 175 ALA AAA N   1 ? 
ATOM   1267 C  CA  . ALA A 1 175 ? 3.146   22.717  64.438  1.000 151.407 ? 175 ALA AAA CA  1 ? 
ATOM   1268 C  C   . ALA A 1 175 ? 1.865   23.077  65.216  1.000 142.869 ? 175 ALA AAA C   1 ? 
ATOM   1269 O  O   . ALA A 1 175 ? 1.375   22.235  66.001  1.000 139.229 ? 175 ALA AAA O   1 ? 
ATOM   1270 C  CB  . ALA A 1 175 ? 4.375   23.243  65.140  1.000 148.048 ? 175 ALA AAA CB  1 ? 
ATOM   1271 N  N   . ALA A 1 176 ? 1.326   24.282  65.042  1.000 132.526 ? 176 ALA AAA N   1 ? 
ATOM   1272 C  CA  . ALA A 1 176 ? 0.174   24.756  65.832  1.000 122.083 ? 176 ALA AAA CA  1 ? 
ATOM   1273 C  C   . ALA A 1 176 ? -1.117  24.361  65.153  1.000 122.442 ? 176 ALA AAA C   1 ? 
ATOM   1274 O  O   . ALA A 1 176 ? -2.193  24.700  65.649  1.000 121.202 ? 176 ALA AAA O   1 ? 
ATOM   1275 C  CB  . ALA A 1 176 ? 0.250   26.248  66.035  1.000 118.356 ? 176 ALA AAA CB  1 ? 
ATOM   1276 N  N   . CYS A 1 177 ? -0.990  23.662  64.038  1.000 130.292 ? 177 CYS AAA N   1 ? 
ATOM   1277 C  CA  . CYS A 1 177 ? -2.126  23.018  63.373  1.000 137.745 ? 177 CYS AAA CA  1 ? 
ATOM   1278 C  C   . CYS A 1 177 ? -2.095  21.529  63.676  1.000 130.483 ? 177 CYS AAA C   1 ? 
ATOM   1279 O  O   . CYS A 1 177 ? -2.903  21.031  64.476  1.000 124.214 ? 177 CYS AAA O   1 ? 
ATOM   1280 C  CB  . CYS A 1 177 ? -2.086  23.278  61.867  1.000 147.617 ? 177 CYS AAA CB  1 ? 
ATOM   1281 S  SG  . CYS A 1 177 ? -3.494  22.597  60.948  1.000 158.754 ? 177 CYS AAA SG  1 ? 
ATOM   1282 N  N   . LEU A 1 178 ? -1.142  20.831  63.062  1.000 124.255 ? 178 LEU AAA N   1 ? 
ATOM   1283 C  CA  . LEU A 1 178 ? -1.021  19.364  63.112  1.000 117.979 ? 178 LEU AAA CA  1 ? 
ATOM   1284 C  C   . LEU A 1 178 ? -0.968  18.852  64.547  1.000 112.611 ? 178 LEU AAA C   1 ? 
ATOM   1285 O  O   . LEU A 1 178 ? -1.913  18.167  64.951  1.000 113.226 ? 178 LEU AAA O   1 ? 
ATOM   1286 C  CB  . LEU A 1 178 ? 0.219   18.927  62.322  1.000 120.080 ? 178 LEU AAA CB  1 ? 
ATOM   1287 C  CG  . LEU A 1 178 ? 0.329   17.430  62.029  1.000 122.614 ? 178 LEU AAA CG  1 ? 
ATOM   1288 C  CD1 . LEU A 1 178 ? -0.956  16.874  61.428  1.000 124.605 ? 178 LEU AAA CD1 1 ? 
ATOM   1289 C  CD2 . LEU A 1 178 ? 1.500   17.153  61.103  1.000 123.956 ? 178 LEU AAA CD2 1 ? 
ATOM   1290 N  N   . LEU A 1 179 ? 0.107   19.126  65.283  1.000 109.281 ? 179 LEU AAA N   1 ? 
ATOM   1291 C  CA  . LEU A 1 179 ? 0.346   18.500  66.612  1.000 112.631 ? 179 LEU AAA CA  1 ? 
ATOM   1292 C  C   . LEU A 1 179 ? -0.915  18.458  67.485  1.000 114.123 ? 179 LEU AAA C   1 ? 
ATOM   1293 O  O   . LEU A 1 179 ? -1.280  17.386  67.997  1.000 119.124 ? 179 LEU AAA O   1 ? 
ATOM   1294 C  CB  . LEU A 1 179 ? 1.468   19.240  67.347  1.000 115.032 ? 179 LEU AAA CB  1 ? 
ATOM   1295 C  CG  . LEU A 1 179 ? 2.879   18.992  66.826  1.000 122.701 ? 179 LEU AAA CG  1 ? 
ATOM   1296 C  CD1 . LEU A 1 179 ? 3.853   19.989  67.436  1.000 128.523 ? 179 LEU AAA CD1 1 ? 
ATOM   1297 C  CD2 . LEU A 1 179 ? 3.322   17.566  67.113  1.000 123.428 ? 179 LEU AAA CD2 1 ? 
ATOM   1298 N  N   . PRO A 1 180 ? -1.593  19.615  67.692  1.000 117.057 ? 180 PRO AAA N   1 ? 
ATOM   1299 C  CA  . PRO A 1 180 ? -2.855  19.664  68.446  1.000 115.951 ? 180 PRO AAA CA  1 ? 
ATOM   1300 C  C   . PRO A 1 180 ? -3.934  18.636  68.071  1.000 113.493 ? 180 PRO AAA C   1 ? 
ATOM   1301 O  O   . PRO A 1 180 ? -4.693  18.196  68.945  1.000 109.330 ? 180 PRO AAA O   1 ? 
ATOM   1302 C  CB  . PRO A 1 180 ? -3.407  21.060  68.121  1.000 118.744 ? 180 PRO AAA CB  1 ? 
ATOM   1303 C  CG  . PRO A 1 180 ? -2.180  21.900  67.861  1.000 122.308 ? 180 PRO AAA CG  1 ? 
ATOM   1304 C  CD  . PRO A 1 180 ? -1.161  20.955  67.260  1.000 120.906 ? 180 PRO AAA CD  1 ? 
ATOM   1305 N  N   . LYS A 1 181 ? -4.009  18.261  66.797  1.000 112.044 ? 181 LYS AAA N   1 ? 
ATOM   1306 C  CA  . LYS A 1 181 ? -4.906  17.172  66.354  1.000 109.175 ? 181 LYS AAA CA  1 ? 
ATOM   1307 C  C   . LYS A 1 181 ? -4.330  15.842  66.802  1.000 102.424 ? 181 LYS AAA C   1 ? 
ATOM   1308 O  O   . LYS A 1 181 ? -5.070  14.994  67.329  1.000 104.305 ? 181 LYS AAA O   1 ? 
ATOM   1309 C  CB  . LYS A 1 181 ? -5.101  17.208  64.835  1.000 114.127 ? 181 LYS AAA CB  1 ? 
ATOM   1310 C  CG  . LYS A 1 181 ? -5.532  18.559  64.280  1.000 116.772 ? 181 LYS AAA CG  1 ? 
ATOM   1311 C  CD  . LYS A 1 181 ? -6.415  18.478  63.058  1.000 117.693 ? 181 LYS AAA CD  1 ? 
ATOM   1312 C  CE  . LYS A 1 181 ? -7.129  19.782  62.776  1.000 121.404 ? 181 LYS AAA CE  1 ? 
ATOM   1313 N  NZ  . LYS A 1 181 ? -8.403  19.561  62.053  1.000 127.161 ? 181 LYS AAA NZ  1 ? 
ATOM   1314 N  N   . LEU A 1 182 ? -3.031  15.673  66.627  1.000 97.797  ? 182 LEU AAA N   1 ? 
ATOM   1315 C  CA  . LEU A 1 182 ? -2.392  14.385  66.919  1.000 103.893 ? 182 LEU AAA CA  1 ? 
ATOM   1316 C  C   . LEU A 1 182 ? -2.448  14.089  68.417  1.000 111.582 ? 182 LEU AAA C   1 ? 
ATOM   1317 O  O   . LEU A 1 182 ? -2.562  12.920  68.805  1.000 122.224 ? 182 LEU AAA O   1 ? 
ATOM   1318 C  CB  . LEU A 1 182 ? -0.949  14.397  66.406  1.000 108.404 ? 182 LEU AAA CB  1 ? 
ATOM   1319 C  CG  . LEU A 1 182 ? -0.759  14.701  64.917  1.000 114.546 ? 182 LEU AAA CG  1 ? 
ATOM   1320 C  CD1 . LEU A 1 182 ? 0.713   14.607  64.534  1.000 122.940 ? 182 LEU AAA CD1 1 ? 
ATOM   1321 C  CD2 . LEU A 1 182 ? -1.587  13.775  64.040  1.000 111.714 ? 182 LEU AAA CD2 1 ? 
ATOM   1322 N  N   . ASP A 1 183 ? -2.372  15.122  69.241  1.000 119.054 ? 183 ASP AAA N   1 ? 
ATOM   1323 C  CA  . ASP A 1 183 ? -2.600  14.969  70.694  1.000 117.119 ? 183 ASP AAA CA  1 ? 
ATOM   1324 C  C   . ASP A 1 183 ? -4.028  14.521  70.943  1.000 106.079 ? 183 ASP AAA C   1 ? 
ATOM   1325 O  O   . ASP A 1 183 ? -4.251  13.762  71.878  1.000 104.927 ? 183 ASP AAA O   1 ? 
ATOM   1326 C  CB  . ASP A 1 183 ? -2.180  16.249  71.426  1.000 124.303 ? 183 ASP AAA CB  1 ? 
ATOM   1327 C  CG  . ASP A 1 183 ? -0.734  16.646  71.147  1.000 127.326 ? 183 ASP AAA CG  1 ? 
ATOM   1328 O  OD1 . ASP A 1 183 ? 0.149   15.758  71.224  1.000 116.225 ? 183 ASP AAA OD1 1 ? 
ATOM   1329 O  OD2 . ASP A 1 183 ? -0.498  17.835  70.822  1.000 132.567 ? 183 ASP AAA OD2 1 ? 
ATOM   1330 N  N   . GLU A 1 184 ? -4.964  14.972  70.128  1.000 99.871  ? 184 GLU AAA N   1 ? 
ATOM   1331 C  CA  . GLU A 1 184 ? -6.354  14.520  70.314  1.000 103.169 ? 184 GLU AAA CA  1 ? 
ATOM   1332 C  C   . GLU A 1 184 ? -6.522  13.067  69.865  1.000 97.765  ? 184 GLU AAA C   1 ? 
ATOM   1333 O  O   . GLU A 1 184 ? -7.151  12.237  70.564  1.000 91.896  ? 184 GLU AAA O   1 ? 
ATOM   1334 C  CB  . GLU A 1 184 ? -7.337  15.474  69.622  1.000 112.521 ? 184 GLU AAA CB  1 ? 
ATOM   1335 C  CG  . GLU A 1 184 ? -8.620  15.695  70.422  1.000 119.184 ? 184 GLU AAA CG  1 ? 
ATOM   1336 C  CD  . GLU A 1 184 ? -9.722  16.525  69.770  1.000 125.437 ? 184 GLU AAA CD  1 ? 
ATOM   1337 O  OE1 . GLU A 1 184 ? -9.835  16.499  68.528  1.000 140.713 ? 184 GLU AAA OE1 1 ? 
ATOM   1338 O  OE2 . GLU A 1 184 ? -10.484 17.188  70.510  1.000 120.693 ? 184 GLU AAA OE2 1 ? 
ATOM   1339 N  N   . LEU A 1 185 ? -5.933  12.734  68.733  1.000 98.521  ? 185 LEU AAA N   1 ? 
ATOM   1340 C  CA  . LEU A 1 185 ? -6.012  11.361  68.213  1.000 102.194 ? 185 LEU AAA CA  1 ? 
ATOM   1341 C  C   . LEU A 1 185 ? -5.360  10.367  69.172  1.000 103.311 ? 185 LEU AAA C   1 ? 
ATOM   1342 O  O   . LEU A 1 185 ? -5.950  9.319   69.398  1.000 104.268 ? 185 LEU AAA O   1 ? 
ATOM   1343 C  CB  . LEU A 1 185 ? -5.370  11.286  66.824  1.000 107.912 ? 185 LEU AAA CB  1 ? 
ATOM   1344 C  CG  . LEU A 1 185 ? -6.119  12.002  65.699  1.000 108.853 ? 185 LEU AAA CG  1 ? 
ATOM   1345 C  CD1 . LEU A 1 185 ? -5.518  11.638  64.347  1.000 111.442 ? 185 LEU AAA CD1 1 ? 
ATOM   1346 C  CD2 . LEU A 1 185 ? -7.609  11.684  65.721  1.000 105.343 ? 185 LEU AAA CD2 1 ? 
ATOM   1347 N  N   . ARG A 1 186 ? -4.177  10.659  69.710  1.000 108.004 ? 186 ARG AAA N   1 ? 
ATOM   1348 C  CA  . ARG A 1 186 ? -3.505  9.703   70.626  1.000 113.010 ? 186 ARG AAA CA  1 ? 
ATOM   1349 C  C   . ARG A 1 186 ? -4.438  9.406   71.801  1.000 120.358 ? 186 ARG AAA C   1 ? 
ATOM   1350 O  O   . ARG A 1 186 ? -4.783  8.227   72.092  1.000 137.419 ? 186 ARG AAA O   1 ? 
ATOM   1351 C  CB  . ARG A 1 186 ? -2.173  10.270  71.130  1.000 107.580 ? 186 ARG AAA CB  1 ? 
ATOM   1352 N  N   . ASP A 1 187 ? -4.874  10.479  72.435  1.000 124.639 ? 187 ASP AAA N   1 ? 
ATOM   1353 C  CA  . ASP A 1 187 ? -5.871  10.413  73.518  1.000 130.938 ? 187 ASP AAA CA  1 ? 
ATOM   1354 C  C   . ASP A 1 187 ? -7.040  9.530   73.090  1.000 126.042 ? 187 ASP AAA C   1 ? 
ATOM   1355 O  O   . ASP A 1 187 ? -7.272  8.490   73.718  1.000 130.980 ? 187 ASP AAA O   1 ? 
ATOM   1356 C  CB  . ASP A 1 187 ? -6.398  11.802  73.894  1.000 144.368 ? 187 ASP AAA CB  1 ? 
ATOM   1357 C  CG  . ASP A 1 187 ? -5.487  12.597  74.813  1.000 158.769 ? 187 ASP AAA CG  1 ? 
ATOM   1358 O  OD1 . ASP A 1 187 ? -4.266  12.341  74.799  1.000 177.054 ? 187 ASP AAA OD1 1 ? 
ATOM   1359 O  OD2 . ASP A 1 187 ? -6.008  13.474  75.533  1.000 168.196 ? 187 ASP AAA OD2 1 ? 
ATOM   1360 N  N   . GLU A 1 188 ? -7.749  9.916   72.032  1.000 123.129 ? 188 GLU AAA N   1 ? 
ATOM   1361 C  CA  . GLU A 1 188 ? -8.957  9.158   71.590  1.000 126.099 ? 188 GLU AAA CA  1 ? 
ATOM   1362 C  C   . GLU A 1 188 ? -8.656  7.658   71.338  1.000 121.069 ? 188 GLU AAA C   1 ? 
ATOM   1363 O  O   . GLU A 1 188 ? -9.406  6.748   71.788  1.000 115.756 ? 188 GLU AAA O   1 ? 
ATOM   1364 C  CB  . GLU A 1 188 ? -9.598  9.811   70.360  1.000 132.406 ? 188 GLU AAA CB  1 ? 
ATOM   1365 C  CG  . GLU A 1 188 ? -11.035 9.355   70.120  1.000 134.643 ? 188 GLU AAA CG  1 ? 
ATOM   1366 C  CD  . GLU A 1 188 ? -11.870 10.162  69.132  1.000 137.635 ? 188 GLU AAA CD  1 ? 
ATOM   1367 O  OE1 . GLU A 1 188 ? -11.611 11.373  68.968  1.000 140.903 ? 188 GLU AAA OE1 1 ? 
ATOM   1368 O  OE2 . GLU A 1 188 ? -12.792 9.573   68.527  1.000 135.999 ? 188 GLU AAA OE2 1 ? 
ATOM   1369 N  N   . GLY A 1 189 ? -7.569  7.393   70.623  1.000 117.812 ? 189 GLY AAA N   1 ? 
ATOM   1370 C  CA  . GLY A 1 189 ? -7.139  6.021   70.304  1.000 113.095 ? 189 GLY AAA CA  1 ? 
ATOM   1371 C  C   . GLY A 1 189 ? -6.886  5.216   71.554  1.000 111.630 ? 189 GLY AAA C   1 ? 
ATOM   1372 O  O   . GLY A 1 189 ? -7.320  4.052   71.640  1.000 113.255 ? 189 GLY AAA O   1 ? 
ATOM   1373 N  N   . LYS A 1 190 ? -6.210  5.838   72.518  1.000 116.581 ? 190 LYS AAA N   1 ? 
ATOM   1374 C  CA  . LYS A 1 190 ? -5.951  5.174   73.824  1.000 117.819 ? 190 LYS AAA CA  1 ? 
ATOM   1375 C  C   . LYS A 1 190 ? -7.258  4.752   74.506  1.000 102.572 ? 190 LYS AAA C   1 ? 
ATOM   1376 O  O   . LYS A 1 190 ? -7.367  3.596   74.956  1.000 102.901 ? 190 LYS AAA O   1 ? 
ATOM   1377 C  CB  . LYS A 1 190 ? -5.071  6.051   74.726  1.000 129.811 ? 190 LYS AAA CB  1 ? 
ATOM   1378 C  CG  . LYS A 1 190 ? -3.580  5.989   74.410  1.000 140.513 ? 190 LYS AAA CG  1 ? 
ATOM   1379 C  CD  . LYS A 1 190 ? -2.674  6.539   75.494  1.000 149.507 ? 190 LYS AAA CD  1 ? 
ATOM   1380 C  CE  . LYS A 1 190 ? -1.219  6.182   75.266  1.000 160.352 ? 190 LYS AAA CE  1 ? 
ATOM   1381 N  NZ  . LYS A 1 190 ? -0.339  6.712   76.335  1.000 165.249 ? 190 LYS AAA NZ  1 ? 
ATOM   1382 N  N   . ALA A 1 191 ? -8.228  5.656   74.578  1.000 89.490  ? 191 ALA AAA N   1 ? 
ATOM   1383 C  CA  . ALA A 1 191 ? -9.587  5.335   75.065  1.000 86.073  ? 191 ALA AAA CA  1 ? 
ATOM   1384 C  C   . ALA A 1 191 ? -10.237 4.204   74.260  1.000 84.187  ? 191 ALA AAA C   1 ? 
ATOM   1385 O  O   . ALA A 1 191 ? -10.631 3.167   74.835  1.000 82.782  ? 191 ALA AAA O   1 ? 
ATOM   1386 C  CB  . ALA A 1 191 ? -10.441 6.577   75.031  1.000 86.116  ? 191 ALA AAA CB  1 ? 
ATOM   1387 N  N   . SER A 1 192 ? -10.369 4.383   72.950  1.000 84.953  ? 192 SER AAA N   1 ? 
ATOM   1388 C  CA  . SER A 1 192 ? -11.015 3.335   72.125  1.000 85.314  ? 192 SER AAA CA  1 ? 
ATOM   1389 C  C   . SER A 1 192 ? -10.372 1.973   72.391  1.000 85.030  ? 192 SER AAA C   1 ? 
ATOM   1390 O  O   . SER A 1 192 ? -11.088 0.997   72.650  1.000 79.781  ? 192 SER AAA O   1 ? 
ATOM   1391 C  CB  . SER A 1 192 ? -10.978 3.667   70.657  1.000 86.593  ? 192 SER AAA CB  1 ? 
ATOM   1392 O  OG  . SER A 1 192 ? -11.268 2.513   69.878  1.000 86.399  ? 192 SER AAA OG  1 ? 
ATOM   1393 N  N   . SER A 1 193 ? -9.044  1.915   72.323  1.000 88.812  ? 193 SER AAA N   1 ? 
ATOM   1394 C  CA  . SER A 1 193 ? -8.301  0.644   72.514  1.000 88.241  ? 193 SER AAA CA  1 ? 
ATOM   1395 C  C   . SER A 1 193 ? -8.649  -0.039  73.830  1.000 92.890  ? 193 SER AAA C   1 ? 
ATOM   1396 O  O   . SER A 1 193 ? -8.944  -1.263  73.860  1.000 104.455 ? 193 SER AAA O   1 ? 
ATOM   1397 C  CB  . SER A 1 193 ? -6.810  0.863   72.451  1.000 88.201  ? 193 SER AAA CB  1 ? 
ATOM   1398 O  OG  . SER A 1 193 ? -6.107  -0.232  73.030  1.000 85.822  ? 193 SER AAA OG  1 ? 
ATOM   1399 N  N   . ALA A 1 194 ? -8.584  0.759   74.892  1.000 92.577  ? 194 ALA AAA N   1 ? 
ATOM   1400 C  CA  . ALA A 1 194 ? -8.884  0.324   76.268  1.000 89.382  ? 194 ALA AAA CA  1 ? 
ATOM   1401 C  C   . ALA A 1 194 ? -10.328 -0.153  76.379  1.000 83.822  ? 194 ALA AAA C   1 ? 
ATOM   1402 O  O   . ALA A 1 194 ? -10.585 -1.191  77.015  1.000 80.752  ? 194 ALA AAA O   1 ? 
ATOM   1403 C  CB  . ALA A 1 194 ? -8.611  1.443   77.245  1.000 89.738  ? 194 ALA AAA CB  1 ? 
ATOM   1404 N  N   . LYS A 1 195 ? -11.245 0.597   75.777  1.000 82.197  ? 195 LYS AAA N   1 ? 
ATOM   1405 C  CA  . LYS A 1 195 ? -12.679 0.247   75.781  1.000 86.798  ? 195 LYS AAA CA  1 ? 
ATOM   1406 C  C   . LYS A 1 195 ? -12.865 -1.090  75.066  1.000 83.268  ? 195 LYS AAA C   1 ? 
ATOM   1407 O  O   . LYS A 1 195 ? -13.592 -1.975  75.552  1.000 79.137  ? 195 LYS AAA O   1 ? 
ATOM   1408 C  CB  . LYS A 1 195 ? -13.480 1.357   75.090  1.000 94.697  ? 195 LYS AAA CB  1 ? 
ATOM   1409 C  CG  . LYS A 1 195 ? -14.990 1.299   75.288  1.000 98.519  ? 195 LYS AAA CG  1 ? 
ATOM   1410 N  N   . GLN A 1 196 ? -12.200 -1.243  73.928  1.000 84.244  ? 196 GLN AAA N   1 ? 
ATOM   1411 C  CA  . GLN A 1 196 ? -12.323 -2.486  73.138  1.000 82.901  ? 196 GLN AAA CA  1 ? 
ATOM   1412 C  C   . GLN A 1 196 ? -11.764 -3.663  73.917  1.000 76.886  ? 196 GLN AAA C   1 ? 
ATOM   1413 O  O   . GLN A 1 196 ? -12.405 -4.740  73.969  1.000 74.001  ? 196 GLN AAA O   1 ? 
ATOM   1414 C  CB  . GLN A 1 196 ? -11.597 -2.370  71.796  1.000 87.080  ? 196 GLN AAA CB  1 ? 
ATOM   1415 C  CG  . GLN A 1 196 ? -11.725 -3.609  70.915  1.000 86.433  ? 196 GLN AAA CG  1 ? 
ATOM   1416 C  CD  . GLN A 1 196 ? -13.145 -3.955  70.538  1.000 87.232  ? 196 GLN AAA CD  1 ? 
ATOM   1417 O  OE1 . GLN A 1 196 ? -13.427 -5.078  70.129  1.000 86.728  ? 196 GLN AAA OE1 1 ? 
ATOM   1418 N  NE2 . GLN A 1 196 ? -14.049 -2.993  70.656  1.000 88.802  ? 196 GLN AAA NE2 1 ? 
ATOM   1419 N  N   . ARG A 1 197 ? -10.584 -3.454  74.488  1.000 75.896  ? 197 ARG AAA N   1 ? 
ATOM   1420 C  CA  . ARG A 1 197 ? -9.923  -4.514  75.267  1.000 77.252  ? 197 ARG AAA CA  1 ? 
ATOM   1421 C  C   . ARG A 1 197 ? -10.908 -5.112  76.286  1.000 76.970  ? 197 ARG AAA C   1 ? 
ATOM   1422 O  O   . ARG A 1 197 ? -10.929 -6.359  76.449  1.000 86.731  ? 197 ARG AAA O   1 ? 
ATOM   1423 C  CB  . ARG A 1 197 ? -8.689  -4.003  76.017  1.000 81.427  ? 197 ARG AAA CB  1 ? 
ATOM   1424 C  CG  . ARG A 1 197 ? -7.896  -5.093  76.728  1.000 83.603  ? 197 ARG AAA CG  1 ? 
ATOM   1425 C  CD  . ARG A 1 197 ? -7.265  -6.063  75.746  1.000 88.529  ? 197 ARG AAA CD  1 ? 
ATOM   1426 N  NE  . ARG A 1 197 ? -6.481  -7.111  76.391  1.000 94.606  ? 197 ARG AAA NE  1 ? 
ATOM   1427 C  CZ  . ARG A 1 197 ? -6.912  -8.340  76.684  1.000 100.094 ? 197 ARG AAA CZ  1 ? 
ATOM   1428 N  NH1 . ARG A 1 197 ? -8.151  -8.712  76.404  1.000 100.530 ? 197 ARG AAA NH1 1 ? 
ATOM   1429 N  NH2 . ARG A 1 197 ? -6.093  -9.202  77.266  1.000 104.044 ? 197 ARG AAA NH2 1 ? 
ATOM   1430 N  N   . LEU A 1 198 ? -11.728 -4.270  76.933  1.000 72.518  ? 198 LEU AAA N   1 ? 
ATOM   1431 C  CA  . LEU A 1 198 ? -12.789 -4.740  77.872  1.000 69.768  ? 198 LEU AAA CA  1 ? 
ATOM   1432 C  C   . LEU A 1 198 ? -13.764 -5.669  77.168  1.000 72.566  ? 198 LEU AAA C   1 ? 
ATOM   1433 O  O   . LEU A 1 198 ? -14.064 -6.784  77.634  1.000 73.708  ? 198 LEU AAA O   1 ? 
ATOM   1434 C  CB  . LEU A 1 198 ? -13.525 -3.533  78.455  1.000 66.838  ? 198 LEU AAA CB  1 ? 
ATOM   1435 C  CG  . LEU A 1 198 ? -14.650 -3.875  79.427  1.000 66.222  ? 198 LEU AAA CG  1 ? 
ATOM   1436 C  CD1 . LEU A 1 198 ? -14.181 -4.884  80.462  1.000 65.765  ? 198 LEU AAA CD1 1 ? 
ATOM   1437 C  CD2 . LEU A 1 198 ? -15.175 -2.620  80.105  1.000 67.984  ? 198 LEU AAA CD2 1 ? 
ATOM   1438 N  N   . LYS A 1 199 ? -14.236 -5.213  76.029  1.000 75.382  ? 199 LYS AAA N   1 ? 
ATOM   1439 C  CA  . LYS A 1 199 ? -15.103 -6.062  75.218  1.000 75.562  ? 199 LYS AAA CA  1 ? 
ATOM   1440 C  C   . LYS A 1 199 ? -14.413 -7.393  74.971  1.000 72.277  ? 199 LYS AAA C   1 ? 
ATOM   1441 O  O   . LYS A 1 199 ? -15.000 -8.440  75.218  1.000 66.303  ? 199 LYS AAA O   1 ? 
ATOM   1442 C  CB  . LYS A 1 199 ? -15.516 -5.359  73.923  1.000 80.415  ? 199 LYS AAA CB  1 ? 
ATOM   1443 C  CG  . LYS A 1 199 ? -16.253 -4.043  74.134  1.000 86.695  ? 199 LYS AAA CG  1 ? 
ATOM   1444 C  CD  . LYS A 1 199 ? -17.087 -3.606  72.952  1.000 93.207  ? 199 LYS AAA CD  1 ? 
ATOM   1445 C  CE  . LYS A 1 199 ? -17.906 -2.362  73.230  1.000 98.399  ? 199 LYS AAA CE  1 ? 
ATOM   1446 N  NZ  . LYS A 1 199 ? -17.041 -1.174  73.425  1.000 100.439 ? 199 LYS AAA NZ  1 ? 
ATOM   1447 N  N   . CYS A 1 200 ? -13.177 -7.384  74.520  1.000 77.144  ? 200 CYS AAA N   1 ? 
ATOM   1448 C  CA  . CYS A 1 200 ? -12.550 -8.683  74.176  1.000 82.576  ? 200 CYS AAA CA  1 ? 
ATOM   1449 C  C   . CYS A 1 200 ? -12.348 -9.578  75.413  1.000 78.338  ? 200 CYS AAA C   1 ? 
ATOM   1450 O  O   . CYS A 1 200 ? -12.688 -10.788 75.392  1.000 77.320  ? 200 CYS AAA O   1 ? 
ATOM   1451 C  CB  . CYS A 1 200 ? -11.254 -8.479  73.400  1.000 95.132  ? 200 CYS AAA CB  1 ? 
ATOM   1452 S  SG  . CYS A 1 200 ? -11.506 -7.714  71.774  1.000 115.380 ? 200 CYS AAA SG  1 ? 
ATOM   1453 N  N   . ALA A 1 201 ? -11.840 -9.018  76.504  1.000 81.892  ? 201 ALA AAA N   1 ? 
ATOM   1454 C  CA  . ALA A 1 201 ? -11.718 -9.784  77.776  1.000 85.695  ? 201 ALA AAA CA  1 ? 
ATOM   1455 C  C   . ALA A 1 201 ? -13.067 -10.339 78.279  1.000 83.441  ? 201 ALA AAA C   1 ? 
ATOM   1456 O  O   . ALA A 1 201 ? -13.146 -11.500 78.767  1.000 85.549  ? 201 ALA AAA O   1 ? 
ATOM   1457 C  CB  . ALA A 1 201 ? -11.082 -8.914  78.833  1.000 88.900  ? 201 ALA AAA CB  1 ? 
ATOM   1458 N  N   . SER A 1 202 ? -14.118 -9.525  78.214  1.000 80.315  ? 202 SER AAA N   1 ? 
ATOM   1459 C  CA  . SER A 1 202 ? -15.458 -9.969  78.643  1.000 81.581  ? 202 SER AAA CA  1 ? 
ATOM   1460 C  C   . SER A 1 202 ? -15.759 -11.263 77.893  1.000 81.244  ? 202 SER AAA C   1 ? 
ATOM   1461 O  O   . SER A 1 202 ? -16.060 -12.280 78.511  1.000 82.074  ? 202 SER AAA O   1 ? 
ATOM   1462 C  CB  . SER A 1 202 ? -16.502 -8.923  78.385  1.000 85.165  ? 202 SER AAA CB  1 ? 
ATOM   1463 O  OG  . SER A 1 202 ? -16.066 -7.657  78.853  1.000 90.771  ? 202 SER AAA OG  1 ? 
ATOM   1464 N  N   . LEU A 1 203 ? -15.627 -11.218 76.572  1.000 80.731  ? 203 LEU AAA N   1 ? 
ATOM   1465 C  CA  . LEU A 1 203 ? -15.920 -12.378 75.697  1.000 78.069  ? 203 LEU AAA CA  1 ? 
ATOM   1466 C  C   . LEU A 1 203 ? -15.027 -13.551 76.026  1.000 79.526  ? 203 LEU AAA C   1 ? 
ATOM   1467 O  O   . LEU A 1 203 ? -15.532 -14.639 76.219  1.000 78.660  ? 203 LEU AAA O   1 ? 
ATOM   1468 C  CB  . LEU A 1 203 ? -15.718 -11.997 74.225  1.000 76.652  ? 203 LEU AAA CB  1 ? 
ATOM   1469 C  CG  . LEU A 1 203 ? -16.761 -11.079 73.590  1.000 74.293  ? 203 LEU AAA CG  1 ? 
ATOM   1470 C  CD1 . LEU A 1 203 ? -16.330 -10.704 72.182  1.000 76.202  ? 203 LEU AAA CD1 1 ? 
ATOM   1471 C  CD2 . LEU A 1 203 ? -18.135 -11.726 73.560  1.000 71.565  ? 203 LEU AAA CD2 1 ? 
ATOM   1472 N  N   . GLN A 1 204 ? -13.722 -13.324 76.046  1.000 84.841  ? 204 GLN AAA N   1 ? 
ATOM   1473 C  CA  . GLN A 1 204 ? -12.772 -14.444 76.060  1.000 89.419  ? 204 GLN AAA CA  1 ? 
ATOM   1474 C  C   . GLN A 1 204 ? -12.706 -15.078 77.430  1.000 85.534  ? 204 GLN AAA C   1 ? 
ATOM   1475 O  O   . GLN A 1 204 ? -12.699 -16.307 77.519  1.000 85.499  ? 204 GLN AAA O   1 ? 
ATOM   1476 C  CB  . GLN A 1 204 ? -11.406 -13.962 75.578  1.000 96.397  ? 204 GLN AAA CB  1 ? 
ATOM   1477 C  CG  . GLN A 1 204 ? -11.415 -13.624 74.093  1.000 104.067 ? 204 GLN AAA CG  1 ? 
ATOM   1478 C  CD  . GLN A 1 204 ? -10.247 -12.770 73.673  1.000 113.661 ? 204 GLN AAA CD  1 ? 
ATOM   1479 O  OE1 . GLN A 1 204 ? -9.663  -12.041 74.474  1.000 125.846 ? 204 GLN AAA OE1 1 ? 
ATOM   1480 N  NE2 . GLN A 1 204 ? -9.915  -12.840 72.394  1.000 120.455 ? 204 GLN AAA NE2 1 ? 
ATOM   1481 N  N   . LYS A 1 205 ? -12.697 -14.243 78.453  1.000 86.052  ? 205 LYS AAA N   1 ? 
ATOM   1482 C  CA  . LYS A 1 205 ? -12.570 -14.739 79.826  1.000 92.090  ? 205 LYS AAA CA  1 ? 
ATOM   1483 C  C   . LYS A 1 205 ? -13.929 -15.016 80.483  1.000 82.854  ? 205 LYS AAA C   1 ? 
ATOM   1484 O  O   . LYS A 1 205 ? -13.979 -15.825 81.419  1.000 78.624  ? 205 LYS AAA O   1 ? 
ATOM   1485 C  CB  . LYS A 1 205 ? -11.810 -13.739 80.703  1.000 107.119 ? 205 LYS AAA CB  1 ? 
ATOM   1486 C  CG  . LYS A 1 205 ? -10.341 -13.541 80.353  1.000 121.049 ? 205 LYS AAA CG  1 ? 
ATOM   1487 C  CD  . LYS A 1 205 ? -9.574  -12.776 81.419  1.000 132.514 ? 205 LYS AAA CD  1 ? 
ATOM   1488 C  CE  . LYS A 1 205 ? -8.712  -11.661 80.861  1.000 143.871 ? 205 LYS AAA CE  1 ? 
ATOM   1489 N  NZ  . LYS A 1 205 ? -8.354  -10.668 81.904  1.000 151.798 ? 205 LYS AAA NZ  1 ? 
ATOM   1490 N  N   . PHE A 1 206 ? -15.020 -14.375 80.049  1.000 79.298  ? 206 PHE AAA N   1 ? 
ATOM   1491 C  CA  . PHE A 1 206 ? -16.352 -14.626 80.673  1.000 78.902  ? 206 PHE AAA CA  1 ? 
ATOM   1492 C  C   . PHE A 1 206 ? -17.399 -15.212 79.714  1.000 80.567  ? 206 PHE AAA C   1 ? 
ATOM   1493 O  O   . PHE A 1 206 ? -18.498 -15.552 80.179  1.000 77.514  ? 206 PHE AAA O   1 ? 
ATOM   1494 C  CB  . PHE A 1 206 ? -16.823 -13.356 81.385  1.000 78.700  ? 206 PHE AAA CB  1 ? 
ATOM   1495 C  CG  . PHE A 1 206 ? -15.929 -12.962 82.535  1.000 75.166  ? 206 PHE AAA CG  1 ? 
ATOM   1496 C  CD1 . PHE A 1 206 ? -16.200 -13.384 83.828  1.000 71.976  ? 206 PHE AAA CD1 1 ? 
ATOM   1497 C  CD2 . PHE A 1 206 ? -14.790 -12.206 82.315  1.000 73.675  ? 206 PHE AAA CD2 1 ? 
ATOM   1498 C  CE1 . PHE A 1 206 ? -15.364 -13.038 84.877  1.000 69.000  ? 206 PHE AAA CE1 1 ? 
ATOM   1499 C  CE2 . PHE A 1 206 ? -13.956 -11.861 83.366  1.000 70.983  ? 206 PHE AAA CE2 1 ? 
ATOM   1500 C  CZ  . PHE A 1 206 ? -14.245 -12.276 84.644  1.000 68.834  ? 206 PHE AAA CZ  1 ? 
ATOM   1501 N  N   . GLY A 1 207 ? -17.088 -15.340 78.427  1.000 87.682  ? 207 GLY AAA N   1 ? 
ATOM   1502 C  CA  . GLY A 1 207 ? -17.947 -16.057 77.471  1.000 93.374  ? 207 GLY AAA CA  1 ? 
ATOM   1503 C  C   . GLY A 1 207 ? -19.063 -15.184 76.965  1.000 95.626  ? 207 GLY AAA C   1 ? 
ATOM   1504 O  O   . GLY A 1 207 ? -19.258 -14.089 77.493  1.000 98.704  ? 207 GLY AAA O   1 ? 
ATOM   1505 N  N   . GLU A 1 208 ? -19.803 -15.628 75.955  1.000 98.973  ? 208 GLU AAA N   1 ? 
ATOM   1506 C  CA  . GLU A 1 208 ? -20.674 -14.681 75.221  1.000 104.015 ? 208 GLU AAA CA  1 ? 
ATOM   1507 C  C   . GLU A 1 208 ? -21.915 -14.379 76.039  1.000 102.220 ? 208 GLU AAA C   1 ? 
ATOM   1508 O  O   . GLU A 1 208 ? -22.333 -13.214 76.084  1.000 102.535 ? 208 GLU AAA O   1 ? 
ATOM   1509 C  CB  . GLU A 1 208 ? -20.972 -15.176 73.800  1.000 112.179 ? 208 GLU AAA CB  1 ? 
ATOM   1510 C  CG  . GLU A 1 208 ? -22.276 -15.941 73.643  1.000 122.449 ? 208 GLU AAA CG  1 ? 
ATOM   1511 C  CD  . GLU A 1 208 ? -22.592 -16.385 72.222  1.000 130.816 ? 208 GLU AAA CD  1 ? 
ATOM   1512 O  OE1 . GLU A 1 208 ? -21.797 -17.166 71.649  1.000 130.902 ? 208 GLU AAA OE1 1 ? 
ATOM   1513 O  OE2 . GLU A 1 208 ? -23.638 -15.952 71.692  1.000 138.091 ? 208 GLU AAA OE2 1 ? 
ATOM   1514 N  N   . ARG A 1 209 ? -22.454 -15.387 76.704  1.000 105.862 ? 209 ARG AAA N   1 ? 
ATOM   1515 C  CA  . ARG A 1 209 ? -23.578 -15.199 77.643  1.000 112.739 ? 209 ARG AAA CA  1 ? 
ATOM   1516 C  C   . ARG A 1 209 ? -23.453 -13.891 78.424  1.000 112.046 ? 209 ARG AAA C   1 ? 
ATOM   1517 O  O   . ARG A 1 209 ? -24.470 -13.186 78.657  1.000 121.230 ? 209 ARG AAA O   1 ? 
ATOM   1518 C  CB  . ARG A 1 209 ? -23.642 -16.388 78.611  1.000 116.046 ? 209 ARG AAA CB  1 ? 
ATOM   1519 C  CG  . ARG A 1 209 ? -24.783 -16.327 79.618  1.000 114.487 ? 209 ARG AAA CG  1 ? 
ATOM   1520 N  N   . ALA A 1 210 ? -22.237 -13.598 78.846  1.000 104.668 ? 210 ALA AAA N   1 ? 
ATOM   1521 C  CA  . ALA A 1 210 ? -21.926 -12.421 79.660  1.000 101.915 ? 210 ALA AAA CA  1 ? 
ATOM   1522 C  C   . ALA A 1 210 ? -21.935 -11.145 78.840  1.000 96.486  ? 210 ALA AAA C   1 ? 
ATOM   1523 O  O   . ALA A 1 210 ? -22.501 -10.147 79.283  1.000 93.253  ? 210 ALA AAA O   1 ? 
ATOM   1524 C  CB  . ALA A 1 210 ? -20.589 -12.615 80.332  1.000 105.337 ? 210 ALA AAA CB  1 ? 
ATOM   1525 N  N   . PHE A 1 211 ? -21.294 -11.166 77.685  1.000 93.515  ? 211 PHE AAA N   1 ? 
ATOM   1526 C  CA  . PHE A 1 211 ? -21.237 -9.964  76.837  1.000 91.668  ? 211 PHE AAA CA  1 ? 
ATOM   1527 C  C   . PHE A 1 211 ? -22.652 -9.605  76.435  1.000 87.402  ? 211 PHE AAA C   1 ? 
ATOM   1528 O  O   . PHE A 1 211 ? -23.064 -8.439  76.500  1.000 90.733  ? 211 PHE AAA O   1 ? 
ATOM   1529 C  CB  . PHE A 1 211 ? -20.353 -10.160 75.603  1.000 97.101  ? 211 PHE AAA CB  1 ? 
ATOM   1530 C  CG  . PHE A 1 211 ? -20.324 -8.964  74.684  1.000 104.880 ? 211 PHE AAA CG  1 ? 
ATOM   1531 C  CD1 . PHE A 1 211 ? -19.483 -7.889  74.938  1.000 110.009 ? 211 PHE AAA CD1 1 ? 
ATOM   1532 C  CD2 . PHE A 1 211 ? -21.159 -8.896  73.579  1.000 110.325 ? 211 PHE AAA CD2 1 ? 
ATOM   1533 C  CE1 . PHE A 1 211 ? -19.467 -6.783  74.101  1.000 111.602 ? 211 PHE AAA CE1 1 ? 
ATOM   1534 C  CE2 . PHE A 1 211 ? -21.143 -7.788  72.743  1.000 112.579 ? 211 PHE AAA CE2 1 ? 
ATOM   1535 C  CZ  . PHE A 1 211 ? -20.297 -6.735  73.005  1.000 113.067 ? 211 PHE AAA CZ  1 ? 
ATOM   1536 N  N   . LYS A 1 212 ? -23.397 -10.622 76.044  1.000 85.332  ? 212 LYS AAA N   1 ? 
ATOM   1537 C  CA  . LYS A 1 212 ? -24.798 -10.409 75.662  1.000 86.813  ? 212 LYS AAA CA  1 ? 
ATOM   1538 C  C   . LYS A 1 212 ? -25.513 -9.554  76.701  1.000 81.293  ? 212 LYS AAA C   1 ? 
ATOM   1539 O  O   . LYS A 1 212 ? -26.113 -8.554  76.333  1.000 77.590  ? 212 LYS AAA O   1 ? 
ATOM   1540 C  CB  . LYS A 1 212 ? -25.531 -11.729 75.410  1.000 97.378  ? 212 LYS AAA CB  1 ? 
ATOM   1541 C  CG  . LYS A 1 212 ? -25.377 -12.268 73.993  1.000 107.689 ? 212 LYS AAA CG  1 ? 
ATOM   1542 C  CD  . LYS A 1 212 ? -26.513 -13.163 73.537  1.000 114.876 ? 212 LYS AAA CD  1 ? 
ATOM   1543 C  CE  . LYS A 1 212 ? -26.381 -13.592 72.089  1.000 117.230 ? 212 LYS AAA CE  1 ? 
ATOM   1544 N  NZ  . LYS A 1 212 ? -27.305 -14.703 71.759  1.000 116.945 ? 212 LYS AAA NZ  1 ? 
ATOM   1545 N  N   . ALA A 1 213 ? -25.438 -9.926  77.969  1.000 80.015  ? 213 ALA AAA N   1 ? 
ATOM   1546 C  CA  . ALA A 1 213 ? -26.060 -9.138  79.053  1.000 79.839  ? 213 ALA AAA CA  1 ? 
ATOM   1547 C  C   . ALA A 1 213 ? -25.599 -7.678  79.022  1.000 78.679  ? 213 ALA AAA C   1 ? 
ATOM   1548 O  O   . ALA A 1 213 ? -26.402 -6.745  79.168  1.000 71.855  ? 213 ALA AAA O   1 ? 
ATOM   1549 C  CB  . ALA A 1 213 ? -25.746 -9.778  80.383  1.000 80.060  ? 213 ALA AAA CB  1 ? 
ATOM   1550 N  N   . TRP A 1 214 ? -24.309 -7.493  78.826  1.000 86.268  ? 214 TRP AAA N   1 ? 
ATOM   1551 C  CA  . TRP A 1 214 ? -23.685 -6.164  78.783  1.000 92.340  ? 214 TRP AAA CA  1 ? 
ATOM   1552 C  C   . TRP A 1 214 ? -24.328 -5.350  77.686  1.000 84.938  ? 214 TRP AAA C   1 ? 
ATOM   1553 O  O   . TRP A 1 214 ? -24.800 -4.238  77.912  1.000 84.030  ? 214 TRP AAA O   1 ? 
ATOM   1554 C  CB  . TRP A 1 214 ? -22.175 -6.315  78.577  1.000 105.998 ? 214 TRP AAA CB  1 ? 
ATOM   1555 C  CG  . TRP A 1 214 ? -21.398 -5.053  78.759  1.000 116.438 ? 214 TRP AAA CG  1 ? 
ATOM   1556 C  CD1 . TRP A 1 214 ? -20.752 -4.648  79.890  1.000 124.360 ? 214 TRP AAA CD1 1 ? 
ATOM   1557 C  CD2 . TRP A 1 214 ? -21.169 -4.033  77.771  1.000 126.168 ? 214 TRP AAA CD2 1 ? 
ATOM   1558 N  NE1 . TRP A 1 214 ? -20.141 -3.442  79.680  1.000 133.969 ? 214 TRP AAA NE1 1 ? 
ATOM   1559 C  CE2 . TRP A 1 214 ? -20.378 -3.040  78.390  1.000 136.848 ? 214 TRP AAA CE2 1 ? 
ATOM   1560 C  CE3 . TRP A 1 214 ? -21.553 -3.859  76.435  1.000 125.251 ? 214 TRP AAA CE3 1 ? 
ATOM   1561 C  CZ2 . TRP A 1 214 ? -19.967 -1.891  77.712  1.000 140.529 ? 214 TRP AAA CZ2 1 ? 
ATOM   1562 C  CZ3 . TRP A 1 214 ? -21.143 -2.725  75.766  1.000 129.111 ? 214 TRP AAA CZ3 1 ? 
ATOM   1563 C  CH2 . TRP A 1 214 ? -20.357 -1.758  76.398  1.000 134.943 ? 214 TRP AAA CH2 1 ? 
ATOM   1564 N  N   . ALA A 1 215 ? -24.327 -5.936  76.512  1.000 81.876  ? 215 ALA AAA N   1 ? 
ATOM   1565 C  CA  . ALA A 1 215 ? -24.910 -5.282  75.348  1.000 80.938  ? 215 ALA AAA CA  1 ? 
ATOM   1566 C  C   . ALA A 1 215 ? -26.357 -4.956  75.687  1.000 78.157  ? 215 ALA AAA C   1 ? 
ATOM   1567 O  O   . ALA A 1 215 ? -26.730 -3.782  75.696  1.000 77.137  ? 215 ALA AAA O   1 ? 
ATOM   1568 C  CB  . ALA A 1 215 ? -24.802 -6.162  74.130  1.000 83.162  ? 215 ALA AAA CB  1 ? 
ATOM   1569 N  N   . VAL A 1 216 ? -27.136 -5.978  76.009  1.000 78.359  ? 216 VAL AAA N   1 ? 
ATOM   1570 C  CA  . VAL A 1 216 ? -28.575 -5.800  76.316  1.000 84.221  ? 216 VAL AAA CA  1 ? 
ATOM   1571 C  C   . VAL A 1 216 ? -28.711 -4.622  77.264  1.000 93.286  ? 216 VAL AAA C   1 ? 
ATOM   1572 O  O   . VAL A 1 216 ? -29.601 -3.803  77.076  1.000 101.530 ? 216 VAL AAA O   1 ? 
ATOM   1573 C  CB  . VAL A 1 216 ? -29.246 -7.059  76.895  1.000 81.459  ? 216 VAL AAA CB  1 ? 
ATOM   1574 C  CG1 . VAL A 1 216 ? -30.576 -6.733  77.561  1.000 76.773  ? 216 VAL AAA CG1 1 ? 
ATOM   1575 C  CG2 . VAL A 1 216 ? -29.442 -8.121  75.830  1.000 83.679  ? 216 VAL AAA CG2 1 ? 
ATOM   1576 N  N   . ALA A 1 217 ? -27.838 -4.525  78.251  1.000 95.884  ? 217 ALA AAA N   1 ? 
ATOM   1577 C  CA  . ALA A 1 217 ? -27.900 -3.393  79.181  1.000 90.554  ? 217 ALA AAA CA  1 ? 
ATOM   1578 C  C   . ALA A 1 217 ? -27.612 -2.080  78.472  1.000 84.934  ? 217 ALA AAA C   1 ? 
ATOM   1579 O  O   . ALA A 1 217 ? -28.393 -1.141  78.606  1.000 74.582  ? 217 ALA AAA O   1 ? 
ATOM   1580 C  CB  . ALA A 1 217 ? -26.946 -3.618  80.331  1.000 92.318  ? 217 ALA AAA CB  1 ? 
ATOM   1581 N  N   . ARG A 1 218 ? -26.511 -2.014  77.735  1.000 90.769  ? 218 ARG AAA N   1 ? 
ATOM   1582 C  CA  . ARG A 1 218 ? -26.087 -0.721  77.148  1.000 95.158  ? 218 ARG AAA CA  1 ? 
ATOM   1583 C  C   . ARG A 1 218 ? -27.069 -0.255  76.072  1.000 86.873  ? 218 ARG AAA C   1 ? 
ATOM   1584 O  O   . ARG A 1 218 ? -27.598 0.870   76.126  1.000 98.617  ? 218 ARG AAA O   1 ? 
ATOM   1585 C  CB  . ARG A 1 218 ? -24.659 -0.809  76.599  1.000 108.107 ? 218 ARG AAA CB  1 ? 
ATOM   1586 C  CG  . ARG A 1 218 ? -23.983 0.537   76.358  1.000 117.598 ? 218 ARG AAA CG  1 ? 
ATOM   1587 C  CD  . ARG A 1 218 ? -22.508 0.356   76.032  1.000 129.448 ? 218 ARG AAA CD  1 ? 
ATOM   1588 N  NE  . ARG A 1 218 ? -21.912 1.399   75.199  1.000 138.093 ? 218 ARG AAA NE  1 ? 
ATOM   1589 C  CZ  . ARG A 1 218 ? -21.920 1.426   73.863  1.000 144.630 ? 218 ARG AAA CZ  1 ? 
ATOM   1590 N  NH1 . ARG A 1 218 ? -22.511 0.469   73.164  1.000 144.756 ? 218 ARG AAA NH1 1 ? 
ATOM   1591 N  NH2 . ARG A 1 218 ? -21.340 2.429   73.227  1.000 145.898 ? 218 ARG AAA NH2 1 ? 
ATOM   1592 N  N   . LEU A 1 219 ? -27.330 -1.116  75.111  1.000 75.163  ? 219 LEU AAA N   1 ? 
ATOM   1593 C  CA  . LEU A 1 219 ? -28.240 -0.766  74.022  1.000 70.934  ? 219 LEU AAA CA  1 ? 
ATOM   1594 C  C   . LEU A 1 219 ? -29.618 -0.426  74.533  1.000 69.422  ? 219 LEU AAA C   1 ? 
ATOM   1595 O  O   . LEU A 1 219 ? -30.212 0.435   73.946  1.000 69.747  ? 219 LEU AAA O   1 ? 
ATOM   1596 C  CB  . LEU A 1 219 ? -28.356 -1.937  73.042  1.000 67.954  ? 219 LEU AAA CB  1 ? 
ATOM   1597 C  CG  . LEU A 1 219 ? -27.095 -2.308  72.268  1.000 68.647  ? 219 LEU AAA CG  1 ? 
ATOM   1598 C  CD1 . LEU A 1 219 ? -27.463 -3.015  70.974  1.000 67.635  ? 219 LEU AAA CD1 1 ? 
ATOM   1599 C  CD2 . LEU A 1 219 ? -26.235 -1.085  71.973  1.000 69.910  ? 219 LEU AAA CD2 1 ? 
ATOM   1600 N  N   . SER A 1 220 ? -30.129 -1.094  75.555  1.000 70.829  ? 220 SER AAA N   1 ? 
ATOM   1601 C  CA  . SER A 1 220 ? -31.471 -0.747  76.079  1.000 74.563  ? 220 SER AAA CA  1 ? 
ATOM   1602 C  C   . SER A 1 220 ? -31.414 0.678   76.584  1.000 76.559  ? 220 SER AAA C   1 ? 
ATOM   1603 O  O   . SER A 1 220 ? -32.424 1.372   76.544  1.000 75.193  ? 220 SER AAA O   1 ? 
ATOM   1604 C  CB  . SER A 1 220 ? -31.923 -1.672  77.186  1.000 75.874  ? 220 SER AAA CB  1 ? 
ATOM   1605 O  OG  . SER A 1 220 ? -32.294 -2.945  76.687  1.000 77.211  ? 220 SER AAA OG  1 ? 
ATOM   1606 N  N   . GLN A 1 221 ? -30.233 1.078   77.047  1.000 82.383  ? 221 GLN AAA N   1 ? 
ATOM   1607 C  CA  . GLN A 1 221 ? -29.976 2.462   77.488  1.000 83.594  ? 221 GLN AAA CA  1 ? 
ATOM   1608 C  C   . GLN A 1 221 ? -29.835 3.432   76.315  1.000 84.501  ? 221 GLN AAA C   1 ? 
ATOM   1609 O  O   . GLN A 1 221 ? -30.386 4.534   76.419  1.000 82.624  ? 221 GLN AAA O   1 ? 
ATOM   1610 C  CB  . GLN A 1 221 ? -28.702 2.604   78.331  1.000 84.421  ? 221 GLN AAA CB  1 ? 
ATOM   1611 C  CG  . GLN A 1 221 ? -28.891 2.380   79.824  1.000 82.961  ? 221 GLN AAA CG  1 ? 
ATOM   1612 C  CD  . GLN A 1 221 ? -27.671 2.810   80.602  1.000 82.445  ? 221 GLN AAA CD  1 ? 
ATOM   1613 O  OE1 . GLN A 1 221 ? -26.601 3.051   80.041  1.000 82.603  ? 221 GLN AAA OE1 1 ? 
ATOM   1614 N  NE2 . GLN A 1 221 ? -27.825 2.914   81.913  1.000 82.743  ? 221 GLN AAA NE2 1 ? 
ATOM   1615 N  N   . ARG A 1 222 ? -29.097 3.072   75.254  1.000 90.328  ? 222 ARG AAA N   1 ? 
ATOM   1616 C  CA  . ARG A 1 222 ? -29.016 3.957   74.054  1.000 94.364  ? 222 ARG AAA CA  1 ? 
ATOM   1617 C  C   . ARG A 1 222 ? -30.394 4.093   73.396  1.000 96.485  ? 222 ARG AAA C   1 ? 
ATOM   1618 O  O   . ARG A 1 222 ? -30.761 5.215   72.973  1.000 106.220 ? 222 ARG AAA O   1 ? 
ATOM   1619 C  CB  . ARG A 1 222 ? -27.999 3.450   73.022  1.000 98.186  ? 222 ARG AAA CB  1 ? 
ATOM   1620 C  CG  . ARG A 1 222 ? -26.575 3.272   73.536  1.000 104.731 ? 222 ARG AAA CG  1 ? 
ATOM   1621 C  CD  . ARG A 1 222 ? -25.879 4.553   73.962  1.000 112.818 ? 222 ARG AAA CD  1 ? 
ATOM   1622 N  NE  . ARG A 1 222 ? -24.666 4.297   74.735  1.000 122.999 ? 222 ARG AAA NE  1 ? 
ATOM   1623 C  CZ  . ARG A 1 222 ? -24.626 3.919   76.018  1.000 131.165 ? 222 ARG AAA CZ  1 ? 
ATOM   1624 N  NH1 . ARG A 1 222 ? -25.741 3.737   76.710  1.000 129.283 ? 222 ARG AAA NH1 1 ? 
ATOM   1625 N  NH2 . ARG A 1 222 ? -23.459 3.720   76.609  1.000 136.250 ? 222 ARG AAA NH2 1 ? 
ATOM   1626 N  N   . PHE A 1 223 ? -31.167 2.996   73.358  1.000 94.297  ? 223 PHE AAA N   1 ? 
ATOM   1627 C  CA  . PHE A 1 223 ? -32.394 2.862   72.513  1.000 93.893  ? 223 PHE AAA CA  1 ? 
ATOM   1628 C  C   . PHE A 1 223 ? -33.677 2.471   73.266  1.000 96.393  ? 223 PHE AAA C   1 ? 
ATOM   1629 O  O   . PHE A 1 223 ? -34.422 1.569   72.834  1.000 102.755 ? 223 PHE AAA O   1 ? 
ATOM   1630 C  CB  . PHE A 1 223 ? -32.135 1.843   71.400  1.000 92.317  ? 223 PHE AAA CB  1 ? 
ATOM   1631 C  CG  . PHE A 1 223 ? -30.879 2.089   70.604  1.000 93.271  ? 223 PHE AAA CG  1 ? 
ATOM   1632 C  CD1 . PHE A 1 223 ? -30.521 3.373   70.218  1.000 91.758  ? 223 PHE AAA CD1 1 ? 
ATOM   1633 C  CD2 . PHE A 1 223 ? -30.062 1.034   70.227  1.000 95.303  ? 223 PHE AAA CD2 1 ? 
ATOM   1634 C  CE1 . PHE A 1 223 ? -29.368 3.598   69.485  1.000 92.607  ? 223 PHE AAA CE1 1 ? 
ATOM   1635 C  CE2 . PHE A 1 223 ? -28.911 1.260   69.488  1.000 97.581  ? 223 PHE AAA CE2 1 ? 
ATOM   1636 C  CZ  . PHE A 1 223 ? -28.566 2.541   69.119  1.000 96.870  ? 223 PHE AAA CZ  1 ? 
ATOM   1637 N  N   . PRO A 1 224 ? -33.991 3.201   74.362  1.000 101.524 ? 224 PRO AAA N   1 ? 
ATOM   1638 C  CA  . PRO A 1 224 ? -35.158 2.931   75.199  1.000 106.319 ? 224 PRO AAA CA  1 ? 
ATOM   1639 C  C   . PRO A 1 224 ? -36.440 2.569   74.459  1.000 110.292 ? 224 PRO AAA C   1 ? 
ATOM   1640 O  O   . PRO A 1 224 ? -37.134 1.671   74.883  1.000 116.028 ? 224 PRO AAA O   1 ? 
ATOM   1641 C  CB  . PRO A 1 224 ? -35.360 4.249   75.952  1.000 107.153 ? 224 PRO AAA CB  1 ? 
ATOM   1642 C  CG  . PRO A 1 224 ? -33.965 4.805   76.094  1.000 107.491 ? 224 PRO AAA CG  1 ? 
ATOM   1643 C  CD  . PRO A 1 224 ? -33.241 4.372   74.837  1.000 104.608 ? 224 PRO AAA CD  1 ? 
ATOM   1644 N  N   . LYS A 1 225 ? -36.719 3.272   73.369  1.000 108.186 ? 225 LYS AAA N   1 ? 
ATOM   1645 C  CA  . LYS A 1 225 ? -38.004 3.130   72.657  1.000 108.060 ? 225 LYS AAA CA  1 ? 
ATOM   1646 C  C   . LYS A 1 225 ? -38.103 1.789   71.959  1.000 110.080 ? 225 LYS AAA C   1 ? 
ATOM   1647 O  O   . LYS A 1 225 ? -39.226 1.339   71.672  1.000 112.601 ? 225 LYS AAA O   1 ? 
ATOM   1648 C  CB  . LYS A 1 225 ? -38.193 4.290   71.677  1.000 107.876 ? 225 LYS AAA CB  1 ? 
ATOM   1649 C  CG  . LYS A 1 225 ? -38.365 5.655   72.334  1.000 107.037 ? 225 LYS AAA CG  1 ? 
ATOM   1650 C  CD  . LYS A 1 225 ? -39.785 5.964   72.774  1.000 102.366 ? 225 LYS AAA CD  1 ? 
ATOM   1651 C  CE  . LYS A 1 225 ? -39.875 7.180   73.671  1.000 97.399  ? 225 LYS AAA CE  1 ? 
ATOM   1652 N  NZ  . LYS A 1 225 ? -39.326 8.397   73.027  1.000 95.083  ? 225 LYS AAA NZ  1 ? 
ATOM   1653 N  N   . ALA A 1 226 ? -36.971 1.142   71.743  1.000 112.818 ? 226 ALA AAA N   1 ? 
ATOM   1654 C  CA  . ALA A 1 226 ? -36.937 -0.110  70.978  1.000 112.785 ? 226 ALA AAA CA  1 ? 
ATOM   1655 C  C   . ALA A 1 226 ? -37.569 -1.287  71.736  1.000 110.645 ? 226 ALA AAA C   1 ? 
ATOM   1656 O  O   . ALA A 1 226 ? -37.171 -1.585  72.879  1.000 105.260 ? 226 ALA AAA O   1 ? 
ATOM   1657 C  CB  . ALA A 1 226 ? -35.514 -0.420  70.583  1.000 118.107 ? 226 ALA AAA CB  1 ? 
ATOM   1658 N  N   . GLU A 1 227 ? -38.485 -1.985  71.069  1.000 112.636 ? 227 GLU AAA N   1 ? 
ATOM   1659 C  CA  . GLU A 1 227 ? -39.064 -3.251  71.570  1.000 116.819 ? 227 GLU AAA CA  1 ? 
ATOM   1660 C  C   . GLU A 1 227 ? -37.952 -4.264  71.801  1.000 119.809 ? 227 GLU AAA C   1 ? 
ATOM   1661 O  O   . GLU A 1 227 ? -37.045 -4.386  70.962  1.000 130.089 ? 227 GLU AAA O   1 ? 
ATOM   1662 C  CB  . GLU A 1 227 ? -40.061 -3.840  70.568  1.000 119.332 ? 227 GLU AAA CB  1 ? 
ATOM   1663 C  CG  . GLU A 1 227 ? -41.260 -2.952  70.289  1.000 119.950 ? 227 GLU AAA CG  1 ? 
ATOM   1664 C  CD  . GLU A 1 227 ? -42.298 -2.899  71.395  1.000 117.142 ? 227 GLU AAA CD  1 ? 
ATOM   1665 O  OE1 . GLU A 1 227 ? -42.007 -3.386  72.503  1.000 118.168 ? 227 GLU AAA OE1 1 ? 
ATOM   1666 O  OE2 . GLU A 1 227 ? -43.394 -2.364  71.144  1.000 117.121 ? 227 GLU AAA OE2 1 ? 
ATOM   1667 N  N   . PHE A 1 228 ? -38.049 -5.009  72.889  1.000 117.817 ? 228 PHE AAA N   1 ? 
ATOM   1668 C  CA  . PHE A 1 228 ? -37.069 -6.061  73.255  1.000 117.147 ? 228 PHE AAA CA  1 ? 
ATOM   1669 C  C   . PHE A 1 228 ? -36.572 -6.825  72.029  1.000 112.629 ? 228 PHE AAA C   1 ? 
ATOM   1670 O  O   . PHE A 1 228 ? -35.353 -6.904  71.765  1.000 121.939 ? 228 PHE AAA O   1 ? 
ATOM   1671 C  CB  . PHE A 1 228 ? -37.694 -7.016  74.275  1.000 121.160 ? 228 PHE AAA CB  1 ? 
ATOM   1672 C  CG  . PHE A 1 228 ? -36.773 -8.105  74.762  1.000 120.753 ? 228 PHE AAA CG  1 ? 
ATOM   1673 C  CD1 . PHE A 1 228 ? -35.724 -7.815  75.621  1.000 118.454 ? 228 PHE AAA CD1 1 ? 
ATOM   1674 C  CD2 . PHE A 1 228 ? -36.961 -9.421  74.370  1.000 120.470 ? 228 PHE AAA CD2 1 ? 
ATOM   1675 C  CE1 . PHE A 1 228 ? -34.878 -8.815  76.074  1.000 116.868 ? 228 PHE AAA CE1 1 ? 
ATOM   1676 C  CE2 . PHE A 1 228 ? -36.115 -10.421 74.824  1.000 122.097 ? 228 PHE AAA CE2 1 ? 
ATOM   1677 C  CZ  . PHE A 1 228 ? -35.075 -10.116 75.674  1.000 120.639 ? 228 PHE AAA CZ  1 ? 
ATOM   1678 N  N   . ALA A 1 229 ? -37.519 -7.356  71.274  1.000 103.828 ? 229 ALA AAA N   1 ? 
ATOM   1679 C  CA  . ALA A 1 229 ? -37.264 -8.132  70.050  1.000 104.543 ? 229 ALA AAA CA  1 ? 
ATOM   1680 C  C   . ALA A 1 229 ? -36.170 -7.537  69.151  1.000 105.462 ? 229 ALA AAA C   1 ? 
ATOM   1681 O  O   . ALA A 1 229 ? -35.380 -8.289  68.550  1.000 105.316 ? 229 ALA AAA O   1 ? 
ATOM   1682 C  CB  . ALA A 1 229 ? -38.554 -8.264  69.283  1.000 106.114 ? 229 ALA AAA CB  1 ? 
ATOM   1683 N  N   . GLU A 1 230 ? -36.148 -6.211  69.041  1.000 107.527 ? 230 GLU AAA N   1 ? 
ATOM   1684 C  CA  . GLU A 1 230 ? -35.185 -5.457  68.200  1.000 111.302 ? 230 GLU AAA CA  1 ? 
ATOM   1685 C  C   . GLU A 1 230 ? -33.804 -5.417  68.840  1.000 106.675 ? 230 GLU AAA C   1 ? 
ATOM   1686 O  O   . GLU A 1 230 ? -32.748 -5.585  68.160  1.000 105.546 ? 230 GLU AAA O   1 ? 
ATOM   1687 C  CB  . GLU A 1 230 ? -35.715 -4.037  68.001  1.000 117.375 ? 230 GLU AAA CB  1 ? 
ATOM   1688 C  CG  . GLU A 1 230 ? -35.204 -3.394  66.733  1.000 126.954 ? 230 GLU AAA CG  1 ? 
ATOM   1689 C  CD  . GLU A 1 230 ? -35.531 -4.202  65.489  1.000 132.056 ? 230 GLU AAA CD  1 ? 
ATOM   1690 O  OE1 . GLU A 1 230 ? -36.703 -4.614  65.339  1.000 136.562 ? 230 GLU AAA OE1 1 ? 
ATOM   1691 O  OE2 . GLU A 1 230 ? -34.604 -4.457  64.697  1.000 132.788 ? 230 GLU AAA OE2 1 ? 
ATOM   1692 N  N   . VAL A 1 231 ? -33.835 -5.188  70.144  1.000 102.009 ? 231 VAL AAA N   1 ? 
ATOM   1693 C  CA  . VAL A 1 231 ? -32.629 -5.040  70.976  1.000 99.263  ? 231 VAL AAA CA  1 ? 
ATOM   1694 C  C   . VAL A 1 231 ? -31.915 -6.384  71.007  1.000 100.542 ? 231 VAL AAA C   1 ? 
ATOM   1695 O  O   . VAL A 1 231 ? -30.670 -6.417  70.974  1.000 108.440 ? 231 VAL AAA O   1 ? 
ATOM   1696 C  CB  . VAL A 1 231 ? -32.975 -4.553  72.399  1.000 96.123  ? 231 VAL AAA CB  1 ? 
ATOM   1697 C  CG1 . VAL A 1 231 ? -31.736 -4.411  73.270  1.000 99.225  ? 231 VAL AAA CG1 1 ? 
ATOM   1698 C  CG2 . VAL A 1 231 ? -33.754 -3.246  72.383  1.000 95.048  ? 231 VAL AAA CG2 1 ? 
ATOM   1699 N  N   . SER A 1 232 ? -32.692 -7.459  71.075  1.000 96.652  ? 232 SER AAA N   1 ? 
ATOM   1700 C  CA  . SER A 1 232 ? -32.140 -8.826  71.079  1.000 92.522  ? 232 SER AAA CA  1 ? 
ATOM   1701 C  C   . SER A 1 232 ? -31.368 -9.050  69.787  1.000 92.075  ? 232 SER AAA C   1 ? 
ATOM   1702 O  O   . SER A 1 232 ? -30.203 -9.517  69.805  1.000 103.933 ? 232 SER AAA O   1 ? 
ATOM   1703 C  CB  . SER A 1 232 ? -33.225 -9.857  71.261  1.000 89.516  ? 232 SER AAA CB  1 ? 
ATOM   1704 O  OG  . SER A 1 232 ? -33.928 -9.643  72.478  1.000 87.059  ? 232 SER AAA OG  1 ? 
ATOM   1705 N  N   . LYS A 1 233 ? -32.013 -8.669  68.697  1.000 87.847  ? 233 LYS AAA N   1 ? 
ATOM   1706 C  CA  . LYS A 1 233 ? -31.410 -8.754  67.364  1.000 90.952  ? 233 LYS AAA CA  1 ? 
ATOM   1707 C  C   . LYS A 1 233 ? -30.122 -7.940  67.346  1.000 99.346  ? 233 LYS AAA C   1 ? 
ATOM   1708 O  O   . LYS A 1 233 ? -29.052 -8.456  66.966  1.000 103.173 ? 233 LYS AAA O   1 ? 
ATOM   1709 C  CB  . LYS A 1 233 ? -32.405 -8.327  66.279  1.000 88.114  ? 233 LYS AAA CB  1 ? 
ATOM   1710 C  CG  . LYS A 1 233 ? -32.081 -8.818  64.870  1.000 89.254  ? 233 LYS AAA CG  1 ? 
ATOM   1711 C  CD  . LYS A 1 233 ? -31.252 -7.845  64.038  1.000 91.139  ? 233 LYS AAA CD  1 ? 
ATOM   1712 C  CE  . LYS A 1 233 ? -31.198 -8.174  62.555  1.000 89.579  ? 233 LYS AAA CE  1 ? 
ATOM   1713 N  NZ  . LYS A 1 233 ? -30.612 -9.509  62.288  1.000 88.890  ? 233 LYS AAA NZ  1 ? 
ATOM   1714 N  N   . LEU A 1 234 ? -30.202 -6.693  67.773  1.000 102.080 ? 234 LEU AAA N   1 ? 
ATOM   1715 C  CA  . LEU A 1 234 ? -28.996 -5.859  67.705  1.000 97.961  ? 234 LEU AAA CA  1 ? 
ATOM   1716 C  C   . LEU A 1 234 ? -27.893 -6.541  68.496  1.000 94.172  ? 234 LEU AAA C   1 ? 
ATOM   1717 O  O   . LEU A 1 234 ? -26.778 -6.764  67.995  1.000 93.209  ? 234 LEU AAA O   1 ? 
ATOM   1718 C  CB  . LEU A 1 234 ? -29.291 -4.447  68.219  1.000 100.347 ? 234 LEU AAA CB  1 ? 
ATOM   1719 C  CG  . LEU A 1 234 ? -30.169 -3.586  67.310  1.000 100.471 ? 234 LEU AAA CG  1 ? 
ATOM   1720 C  CD1 . LEU A 1 234 ? -30.388 -2.214  67.929  1.000 104.453 ? 234 LEU AAA CD1 1 ? 
ATOM   1721 C  CD2 . LEU A 1 234 ? -29.572 -3.450  65.916  1.000 97.376  ? 234 LEU AAA CD2 1 ? 
ATOM   1722 N  N   . VAL A 1 235 ? -28.229 -6.910  69.706  1.000 88.830  ? 235 VAL AAA N   1 ? 
ATOM   1723 C  CA  . VAL A 1 235 ? -27.261 -7.590  70.574  1.000 86.368  ? 235 VAL AAA CA  1 ? 
ATOM   1724 C  C   . VAL A 1 235 ? -26.653 -8.788  69.846  1.000 89.131  ? 235 VAL AAA C   1 ? 
ATOM   1725 O  O   . VAL A 1 235 ? -25.430 -8.958  69.843  1.000 102.991 ? 235 VAL AAA O   1 ? 
ATOM   1726 C  CB  . VAL A 1 235 ? -27.901 -7.946  71.934  1.000 80.364  ? 235 VAL AAA CB  1 ? 
ATOM   1727 C  CG1 . VAL A 1 235 ? -27.125 -9.016  72.688  1.000 79.896  ? 235 VAL AAA CG1 1 ? 
ATOM   1728 C  CG2 . VAL A 1 235 ? -28.073 -6.702  72.799  1.000 76.808  ? 235 VAL AAA CG2 1 ? 
ATOM   1729 N  N   . THR A 1 236 ? -27.467 -9.605  69.208  1.000 84.397  ? 236 THR AAA N   1 ? 
ATOM   1730 C  CA  . THR A 1 236 ? -26.899 -10.766 68.489  1.000 83.110  ? 236 THR AAA CA  1 ? 
ATOM   1731 C  C   . THR A 1 236 ? -25.784 -10.341 67.527  1.000 90.559  ? 236 THR AAA C   1 ? 
ATOM   1732 O  O   . THR A 1 236 ? -24.640 -10.887 67.523  1.000 96.560  ? 236 THR AAA O   1 ? 
ATOM   1733 C  CB  . THR A 1 236 ? -27.975 -11.518 67.696  1.000 78.263  ? 236 THR AAA CB  1 ? 
ATOM   1734 O  OG1 . THR A 1 236 ? -28.932 -12.025 68.624  1.000 76.671  ? 236 THR AAA OG1 1 ? 
ATOM   1735 C  CG2 . THR A 1 236 ? -27.424 -12.664 66.878  1.000 76.883  ? 236 THR AAA CG2 1 ? 
ATOM   1736 N  N   . ASP A 1 237 ? -26.153 -9.367  66.709  1.000 95.098  ? 237 ASP AAA N   1 ? 
ATOM   1737 C  CA  . ASP A 1 237 ? -25.368 -8.947  65.538  1.000 101.325 ? 237 ASP AAA CA  1 ? 
ATOM   1738 C  C   . ASP A 1 237 ? -24.084 -8.307  66.029  1.000 101.469 ? 237 ASP AAA C   1 ? 
ATOM   1739 O  O   . ASP A 1 237 ? -22.983 -8.619  65.540  1.000 103.499 ? 237 ASP AAA O   1 ? 
ATOM   1740 C  CB  . ASP A 1 237 ? -26.183 -8.022  64.630  1.000 108.941 ? 237 ASP AAA CB  1 ? 
ATOM   1741 C  CG  . ASP A 1 237 ? -27.362 -8.704  63.953  1.000 117.017 ? 237 ASP AAA CG  1 ? 
ATOM   1742 O  OD1 . ASP A 1 237 ? -27.529 -9.928  64.148  1.000 119.058 ? 237 ASP AAA OD1 1 ? 
ATOM   1743 O  OD2 . ASP A 1 237 ? -28.103 -8.005  63.226  1.000 128.787 ? 237 ASP AAA OD2 1 ? 
ATOM   1744 N  N   . LEU A 1 238 ? -24.247 -7.437  67.003  1.000 100.137 ? 238 LEU AAA N   1 ? 
ATOM   1745 C  CA  . LEU A 1 238 ? -23.111 -6.792  67.657  1.000 97.001  ? 238 LEU AAA CA  1 ? 
ATOM   1746 C  C   . LEU A 1 238 ? -22.189 -7.843  68.269  1.000 95.202  ? 238 LEU AAA C   1 ? 
ATOM   1747 O  O   . LEU A 1 238 ? -20.983 -7.822  68.010  1.000 102.016 ? 238 LEU AAA O   1 ? 
ATOM   1748 C  CB  . LEU A 1 238 ? -23.639 -5.818  68.715  1.000 98.523  ? 238 LEU AAA CB  1 ? 
ATOM   1749 C  CG  . LEU A 1 238 ? -22.600 -4.912  69.374  1.000 105.880 ? 238 LEU AAA CG  1 ? 
ATOM   1750 C  CD1 . LEU A 1 238 ? -21.740 -4.191  68.343  1.000 107.326 ? 238 LEU AAA CD1 1 ? 
ATOM   1751 C  CD2 . LEU A 1 238 ? -23.281 -3.905  70.284  1.000 112.685 ? 238 LEU AAA CD2 1 ? 
ATOM   1752 N  N   . THR A 1 239 ? -22.750 -8.756  69.052  1.000 90.058  ? 239 THR AAA N   1 ? 
ATOM   1753 C  CA  . THR A 1 239 ? -21.944 -9.815  69.684  1.000 85.885  ? 239 THR AAA CA  1 ? 
ATOM   1754 C  C   . THR A 1 239 ? -21.157 -10.522 68.591  1.000 83.445  ? 239 THR AAA C   1 ? 
ATOM   1755 O  O   . THR A 1 239 ? -19.938 -10.727 68.766  1.000 86.288  ? 239 THR AAA O   1 ? 
ATOM   1756 C  CB  . THR A 1 239 ? -22.774 -10.870 70.427  1.000 84.899  ? 239 THR AAA CB  1 ? 
ATOM   1757 O  OG1 . THR A 1 239 ? -23.708 -10.221 71.288  1.000 89.513  ? 239 THR AAA OG1 1 ? 
ATOM   1758 C  CG2 . THR A 1 239 ? -21.921 -11.807 71.255  1.000 84.500  ? 239 THR AAA CG2 1 ? 
ATOM   1759 N  N   . LYS A 1 240 ? -21.830 -10.874 67.495  1.000 81.529  ? 240 LYS AAA N   1 ? 
ATOM   1760 C  CA  . LYS A 1 240 ? -21.108 -11.467 66.341  1.000 82.073  ? 240 LYS AAA CA  1 ? 
ATOM   1761 C  C   . LYS A 1 240 ? -19.964 -10.579 65.845  1.000 79.276  ? 240 LYS AAA C   1 ? 
ATOM   1762 O  O   . LYS A 1 240 ? -18.833 -11.077 65.658  1.000 73.490  ? 240 LYS AAA O   1 ? 
ATOM   1763 C  CB  . LYS A 1 240 ? -22.023 -11.765 65.148  1.000 85.074  ? 240 LYS AAA CB  1 ? 
ATOM   1764 C  CG  . LYS A 1 240 ? -21.293 -12.392 63.964  1.000 88.749  ? 240 LYS AAA CG  1 ? 
ATOM   1765 C  CD  . LYS A 1 240 ? -22.171 -12.806 62.803  1.000 92.787  ? 240 LYS AAA CD  1 ? 
ATOM   1766 C  CE  . LYS A 1 240 ? -21.367 -13.336 61.630  1.000 94.787  ? 240 LYS AAA CE  1 ? 
ATOM   1767 N  NZ  . LYS A 1 240 ? -22.091 -13.210 60.342  1.000 95.035  ? 240 LYS AAA NZ  1 ? 
ATOM   1768 N  N   . VAL A 1 241 ? -20.264 -9.306  65.602  1.000 81.944  ? 241 VAL AAA N   1 ? 
ATOM   1769 C  CA  . VAL A 1 241 ? -19.234 -8.301  65.229  1.000 81.288  ? 241 VAL AAA CA  1 ? 
ATOM   1770 C  C   . VAL A 1 241 ? -18.048 -8.428  66.175  1.000 81.395  ? 241 VAL AAA C   1 ? 
ATOM   1771 O  O   . VAL A 1 241 ? -16.923 -8.624  65.711  1.000 86.323  ? 241 VAL AAA O   1 ? 
ATOM   1772 C  CB  . VAL A 1 241 ? -19.772 -6.853  65.242  1.000 80.924  ? 241 VAL AAA CB  1 ? 
ATOM   1773 C  CG1 . VAL A 1 241 ? -18.646 -5.828  65.179  1.000 80.473  ? 241 VAL AAA CG1 1 ? 
ATOM   1774 C  CG2 . VAL A 1 241 ? -20.776 -6.594  64.129  1.000 81.084  ? 241 VAL AAA CG2 1 ? 
ATOM   1775 N  N   . HIS A 1 242 ? -18.263 -8.292  67.476  1.000 78.807  ? 242 HIS AAA N   1 ? 
ATOM   1776 C  CA  . HIS A 1 242 ? -17.097 -8.211  68.396  1.000 75.048  ? 242 HIS AAA CA  1 ? 
ATOM   1777 C  C   . HIS A 1 242 ? -16.365 -9.546  68.505  1.000 77.546  ? 242 HIS AAA C   1 ? 
ATOM   1778 O  O   . HIS A 1 242 ? -15.113 -9.609  68.349  1.000 83.819  ? 242 HIS AAA O   1 ? 
ATOM   1779 C  CB  . HIS A 1 242 ? -17.527 -7.645  69.756  1.000 69.996  ? 242 HIS AAA CB  1 ? 
ATOM   1780 C  CG  . HIS A 1 242 ? -17.727 -6.170  69.715  1.000 69.236  ? 242 HIS AAA CG  1 ? 
ATOM   1781 N  ND1 . HIS A 1 242 ? -16.670 -5.286  69.722  1.000 70.554  ? 242 HIS AAA ND1 1 ? 
ATOM   1782 C  CD2 . HIS A 1 242 ? -18.846 -5.421  69.621  1.000 70.245  ? 242 HIS AAA CD2 1 ? 
ATOM   1783 C  CE1 . HIS A 1 242 ? -17.129 -4.051  69.655  1.000 72.195  ? 242 HIS AAA CE1 1 ? 
ATOM   1784 N  NE2 . HIS A 1 242 ? -18.464 -4.105  69.595  1.000 71.516  ? 242 HIS AAA NE2 1 ? 
ATOM   1785 N  N   . THR A 1 243 ? -17.131 -10.600 68.748  1.000 77.176  ? 243 THR AAA N   1 ? 
ATOM   1786 C  CA  . THR A 1 243 ? -16.570 -11.965 68.802  1.000 77.670  ? 243 THR AAA CA  1 ? 
ATOM   1787 C  C   . THR A 1 243 ? -15.474 -12.135 67.757  1.000 76.752  ? 243 THR AAA C   1 ? 
ATOM   1788 O  O   . THR A 1 243 ? -14.354 -12.619 68.057  1.000 78.275  ? 243 THR AAA O   1 ? 
ATOM   1789 C  CB  . THR A 1 243 ? -17.633 -13.027 68.499  1.000 80.415  ? 243 THR AAA CB  1 ? 
ATOM   1790 O  OG1 . THR A 1 243 ? -18.634 -12.932 69.510  1.000 88.106  ? 243 THR AAA OG1 1 ? 
ATOM   1791 C  CG2 . THR A 1 243 ? -17.077 -14.434 68.461  1.000 81.064  ? 243 THR AAA CG2 1 ? 
ATOM   1792 N  N   . GLU A 1 244 ? -15.816 -11.740 66.543  1.000 79.448  ? 244 GLU AAA N   1 ? 
ATOM   1793 C  CA  . GLU A 1 244 ? -14.899 -11.839 65.396  1.000 86.548  ? 244 GLU AAA CA  1 ? 
ATOM   1794 C  C   . GLU A 1 244 ? -13.691 -10.917 65.574  1.000 91.587  ? 244 GLU AAA C   1 ? 
ATOM   1795 O  O   . GLU A 1 244 ? -12.539 -11.394 65.532  1.000 102.003 ? 244 GLU AAA O   1 ? 
ATOM   1796 C  CB  . GLU A 1 244 ? -15.701 -11.616 64.116  1.000 90.243  ? 244 GLU AAA CB  1 ? 
ATOM   1797 C  CG  . GLU A 1 244 ? -16.702 -12.735 63.877  1.000 93.870  ? 244 GLU AAA CG  1 ? 
ATOM   1798 C  CD  . GLU A 1 244 ? -17.819 -12.446 62.890  1.000 99.536  ? 244 GLU AAA CD  1 ? 
ATOM   1799 O  OE1 . GLU A 1 244 ? -18.087 -11.259 62.626  1.000 106.151 ? 244 GLU AAA OE1 1 ? 
ATOM   1800 O  OE2 . GLU A 1 244 ? -18.427 -13.417 62.398  1.000 102.465 ? 244 GLU AAA OE2 1 ? 
ATOM   1801 N  N   . CYS A 1 245 ? -13.911 -9.631  65.805  1.000 92.961  ? 245 CYS AAA N   1 ? 
ATOM   1802 C  CA  . CYS A 1 245 ? -12.771 -8.688  65.961  1.000 93.044  ? 245 CYS AAA CA  1 ? 
ATOM   1803 C  C   . CYS A 1 245 ? -11.806 -9.132  67.060  1.000 92.771  ? 245 CYS AAA C   1 ? 
ATOM   1804 O  O   . CYS A 1 245 ? -10.605 -8.797  67.005  1.000 83.104  ? 245 CYS AAA O   1 ? 
ATOM   1805 C  CB  . CYS A 1 245 ? -13.208 -7.276  66.316  1.000 98.159  ? 245 CYS AAA CB  1 ? 
ATOM   1806 S  SG  . CYS A 1 245 ? -13.217 -6.186  64.877  1.000 109.978 ? 245 CYS AAA SG  1 ? 
ATOM   1807 N  N   . CYS A 1 246 ? -12.327 -9.823  68.069  1.000 98.789  ? 246 CYS AAA N   1 ? 
ATOM   1808 C  CA  . CYS A 1 246 ? -11.498 -10.267 69.198  1.000 99.723  ? 246 CYS AAA CA  1 ? 
ATOM   1809 C  C   . CYS A 1 246 ? -10.898 -11.624 68.933  1.000 94.577  ? 246 CYS AAA C   1 ? 
ATOM   1810 O  O   . CYS A 1 246 ? -9.862  -11.953 69.528  1.000 91.347  ? 246 CYS AAA O   1 ? 
ATOM   1811 C  CB  . CYS A 1 246 ? -12.316 -10.340 70.481  1.000 104.863 ? 246 CYS AAA CB  1 ? 
ATOM   1812 S  SG  . CYS A 1 246 ? -13.053 -8.753  70.946  1.000 114.498 ? 246 CYS AAA SG  1 ? 
ATOM   1813 N  N   . HIS A 1 247 ? -11.553 -12.405 68.102  1.000 94.626  ? 247 HIS AAA N   1 ? 
ATOM   1814 C  CA  . HIS A 1 247 ? -10.969 -13.680 67.678  1.000 99.113  ? 247 HIS AAA CA  1 ? 
ATOM   1815 C  C   . HIS A 1 247 ? -10.078 -13.456 66.453  1.000 101.178 ? 247 HIS AAA C   1 ? 
ATOM   1816 O  O   . HIS A 1 247 ? -9.577  -14.435 65.886  1.000 102.477 ? 247 HIS AAA O   1 ? 
ATOM   1817 C  CB  . HIS A 1 247 ? -12.099 -14.705 67.478  1.000 106.205 ? 247 HIS AAA CB  1 ? 
ATOM   1818 C  CG  . HIS A 1 247 ? -11.694 -15.971 66.803  1.000 117.830 ? 247 HIS AAA CG  1 ? 
ATOM   1819 N  ND1 . HIS A 1 247 ? -12.026 -16.236 65.489  1.000 130.171 ? 247 HIS AAA ND1 1 ? 
ATOM   1820 C  CD2 . HIS A 1 247 ? -11.010 -17.048 67.245  1.000 125.002 ? 247 HIS AAA CD2 1 ? 
ATOM   1821 C  CE1 . HIS A 1 247 ? -11.552 -17.415 65.143  1.000 132.610 ? 247 HIS AAA CE1 1 ? 
ATOM   1822 N  NE2 . HIS A 1 247 ? -10.924 -17.936 66.205  1.000 132.715 ? 247 HIS AAA NE2 1 ? 
ATOM   1823 N  N   . GLY A 1 248 ? -9.902  -12.212 66.014  1.000 105.120 ? 248 GLY AAA N   1 ? 
ATOM   1824 C  CA  . GLY A 1 248 ? -8.929  -11.906 64.955  1.000 107.374 ? 248 GLY AAA CA  1 ? 
ATOM   1825 C  C   . GLY A 1 248 ? -9.485  -12.175 63.580  1.000 112.082 ? 248 GLY AAA C   1 ? 
ATOM   1826 O  O   . GLY A 1 248 ? -8.746  -12.552 62.676  1.000 119.482 ? 248 GLY AAA O   1 ? 
ATOM   1827 N  N   . ASP A 1 249 ? -10.779 -11.967 63.430  1.000 118.729 ? 249 ASP AAA N   1 ? 
ATOM   1828 C  CA  . ASP A 1 249 ? -11.485 -12.228 62.172  1.000 122.813 ? 249 ASP AAA CA  1 ? 
ATOM   1829 C  C   . ASP A 1 249 ? -11.877 -10.866 61.656  1.000 126.187 ? 249 ASP AAA C   1 ? 
ATOM   1830 O  O   . ASP A 1 249 ? -13.058 -10.619 61.372  1.000 138.616 ? 249 ASP AAA O   1 ? 
ATOM   1831 C  CB  . ASP A 1 249 ? -12.640 -13.210 62.378  1.000 127.269 ? 249 ASP AAA CB  1 ? 
ATOM   1832 C  CG  . ASP A 1 249 ? -12.161 -14.629 62.625  1.000 131.109 ? 249 ASP AAA CG  1 ? 
ATOM   1833 O  OD1 . ASP A 1 249 ? -11.142 -14.774 63.320  1.000 131.076 ? 249 ASP AAA OD1 1 ? 
ATOM   1834 O  OD2 . ASP A 1 249 ? -12.803 -15.572 62.110  1.000 137.622 ? 249 ASP AAA OD2 1 ? 
ATOM   1835 N  N   . LEU A 1 250 ? -10.876 -10.010 61.510  1.000 119.476 ? 250 LEU AAA N   1 ? 
ATOM   1836 C  CA  . LEU A 1 250 ? -11.109 -8.556  61.355  1.000 112.245 ? 250 LEU AAA CA  1 ? 
ATOM   1837 C  C   . LEU A 1 250 ? -11.897 -8.266  60.080  1.000 107.460 ? 250 LEU AAA C   1 ? 
ATOM   1838 O  O   . LEU A 1 250 ? -12.818 -7.437  60.076  1.000 100.405 ? 250 LEU AAA O   1 ? 
ATOM   1839 C  CB  . LEU A 1 250 ? -9.770  -7.807  61.323  1.000 112.723 ? 250 LEU AAA CB  1 ? 
ATOM   1840 C  CG  . LEU A 1 250 ? -8.672  -8.276  62.281  1.000 112.071 ? 250 LEU AAA CG  1 ? 
ATOM   1841 C  CD1 . LEU A 1 250 ? -7.523  -7.282  62.278  1.000 114.653 ? 250 LEU AAA CD1 1 ? 
ATOM   1842 C  CD2 . LEU A 1 250 ? -9.189  -8.471  63.699  1.000 111.842 ? 250 LEU AAA CD2 1 ? 
ATOM   1843 N  N   . LEU A 1 251 ? -11.536 -8.935  59.004  1.000 104.612 ? 251 LEU AAA N   1 ? 
ATOM   1844 C  CA  . LEU A 1 251 ? -12.185 -8.634  57.728  1.000 103.500 ? 251 LEU AAA CA  1 ? 
ATOM   1845 C  C   . LEU A 1 251 ? -13.670 -8.790  57.976  1.000 105.157 ? 251 LEU AAA C   1 ? 
ATOM   1846 O  O   . LEU A 1 251 ? -14.430 -7.816  57.862  1.000 104.810 ? 251 LEU AAA O   1 ? 
ATOM   1847 C  CB  . LEU A 1 251 ? -11.679 -9.586  56.643  1.000 100.767 ? 251 LEU AAA CB  1 ? 
ATOM   1848 C  CG  . LEU A 1 251 ? -10.198 -9.452  56.305  1.000 102.754 ? 251 LEU AAA CG  1 ? 
ATOM   1849 C  CD1 . LEU A 1 251 ? -9.772  -10.554 55.354  1.000 107.146 ? 251 LEU AAA CD1 1 ? 
ATOM   1850 C  CD2 . LEU A 1 251 ? -9.891  -8.085  55.713  1.000 102.366 ? 251 LEU AAA CD2 1 ? 
ATOM   1851 N  N   . GLU A 1 252 ? -14.050 -9.978  58.398  1.000 107.810 ? 252 GLU AAA N   1 ? 
ATOM   1852 C  CA  . GLU A 1 252 ? -15.471 -10.266 58.582  1.000 111.220 ? 252 GLU AAA CA  1 ? 
ATOM   1853 C  C   . GLU A 1 252 ? -16.038 -9.327  59.632  1.000 110.823 ? 252 GLU AAA C   1 ? 
ATOM   1854 O  O   . GLU A 1 252 ? -17.188 -8.861  59.461  1.000 112.195 ? 252 GLU AAA O   1 ? 
ATOM   1855 C  CB  . GLU A 1 252 ? -15.766 -11.748 58.861  1.000 116.089 ? 252 GLU AAA CB  1 ? 
ATOM   1856 C  CG  . GLU A 1 252 ? -14.766 -12.473 59.744  1.000 120.004 ? 252 GLU AAA CG  1 ? 
ATOM   1857 C  CD  . GLU A 1 252 ? -13.608 -13.151 59.023  1.000 123.339 ? 252 GLU AAA CD  1 ? 
ATOM   1858 O  OE1 . GLU A 1 252 ? -12.824 -12.442 58.360  1.000 129.117 ? 252 GLU AAA OE1 1 ? 
ATOM   1859 O  OE2 . GLU A 1 252 ? -13.486 -14.389 59.134  1.000 121.250 ? 252 GLU AAA OE2 1 ? 
ATOM   1860 N  N   . CYS A 1 253 ? -15.237 -9.019  60.647  1.000 112.186 ? 253 CYS AAA N   1 ? 
ATOM   1861 C  CA  . CYS A 1 253 ? -15.651 -8.070  61.702  1.000 111.650 ? 253 CYS AAA CA  1 ? 
ATOM   1862 C  C   . CYS A 1 253 ? -16.143 -6.759  61.085  1.000 112.323 ? 253 CYS AAA C   1 ? 
ATOM   1863 O  O   . CYS A 1 253 ? -17.286 -6.309  61.366  1.000 118.626 ? 253 CYS AAA O   1 ? 
ATOM   1864 C  CB  . CYS A 1 253 ? -14.510 -7.806  62.677  1.000 109.909 ? 253 CYS AAA CB  1 ? 
ATOM   1865 S  SG  . CYS A 1 253 ? -14.979 -6.694  64.025  1.000 113.546 ? 253 CYS AAA SG  1 ? 
ATOM   1866 N  N   . ALA A 1 254 ? -15.319 -6.184  60.217  1.000 107.523 ? 254 ALA AAA N   1 ? 
ATOM   1867 C  CA  . ALA A 1 254 ? -15.623 -4.890  59.573  1.000 106.183 ? 254 ALA AAA CA  1 ? 
ATOM   1868 C  C   . ALA A 1 254 ? -16.862 -4.976  58.683  1.000 103.284 ? 254 ALA AAA C   1 ? 
ATOM   1869 O  O   . ALA A 1 254 ? -17.708 -4.053  58.697  1.000 100.408 ? 254 ALA AAA O   1 ? 
ATOM   1870 C  CB  . ALA A 1 254 ? -14.414 -4.438  58.791  1.000 106.766 ? 254 ALA AAA CB  1 ? 
ATOM   1871 N  N   . ASP A 1 255 ? -16.948 -6.054  57.911  1.000 101.353 ? 255 ASP AAA N   1 ? 
ATOM   1872 C  CA  . ASP A 1 255 ? -18.059 -6.219  56.966  1.000 104.131 ? 255 ASP AAA CA  1 ? 
ATOM   1873 C  C   . ASP A 1 255 ? -19.302 -6.250  57.818  1.000 103.747 ? 255 ASP AAA C   1 ? 
ATOM   1874 O  O   . ASP A 1 255 ? -20.165 -5.364  57.695  1.000 98.189  ? 255 ASP AAA O   1 ? 
ATOM   1875 C  CB  . ASP A 1 255 ? -17.885 -7.465  56.092  1.000 106.993 ? 255 ASP AAA CB  1 ? 
ATOM   1876 C  CG  . ASP A 1 255 ? -18.927 -7.613  54.990  1.000 110.268 ? 255 ASP AAA CG  1 ? 
ATOM   1877 O  OD1 . ASP A 1 255 ? -19.945 -6.888  55.030  1.000 113.546 ? 255 ASP AAA OD1 1 ? 
ATOM   1878 O  OD2 . ASP A 1 255 ? -18.715 -8.458  54.099  1.000 111.478 ? 255 ASP AAA OD2 1 ? 
ATOM   1879 N  N   . ASP A 1 256 ? -19.336 -7.225  58.703  1.000 106.237 ? 256 ASP AAA N   1 ? 
ATOM   1880 C  CA  . ASP A 1 256 ? -20.487 -7.410  59.592  1.000 107.569 ? 256 ASP AAA CA  1 ? 
ATOM   1881 C  C   . ASP A 1 256 ? -20.861 -6.095  60.295  1.000 112.038 ? 256 ASP AAA C   1 ? 
ATOM   1882 O  O   . ASP A 1 256 ? -22.068 -5.735  60.362  1.000 124.122 ? 256 ASP AAA O   1 ? 
ATOM   1883 C  CB  . ASP A 1 256 ? -20.222 -8.570  60.557  1.000 108.048 ? 256 ASP AAA CB  1 ? 
ATOM   1884 C  CG  . ASP A 1 256 ? -20.002 -9.900  59.848  1.000 110.551 ? 256 ASP AAA CG  1 ? 
ATOM   1885 O  OD1 . ASP A 1 256 ? -20.491 -10.045 58.710  1.000 114.672 ? 256 ASP AAA OD1 1 ? 
ATOM   1886 O  OD2 . ASP A 1 256 ? -19.324 -10.773 60.423  1.000 109.786 ? 256 ASP AAA OD2 1 ? 
ATOM   1887 N  N   . ARG A 1 257 ? -19.862 -5.370  60.796  1.000 113.140 ? 257 ARG AAA N   1 ? 
ATOM   1888 C  CA  . ARG A 1 257 ? -20.095 -4.016  61.362  1.000 118.014 ? 257 ARG AAA CA  1 ? 
ATOM   1889 C  C   . ARG A 1 257 ? -20.811 -3.102  60.364  1.000 120.639 ? 257 ARG AAA C   1 ? 
ATOM   1890 O  O   . ARG A 1 257 ? -21.834 -2.477  60.698  1.000 128.519 ? 257 ARG AAA O   1 ? 
ATOM   1891 C  CB  . ARG A 1 257 ? -18.771 -3.366  61.779  1.000 121.488 ? 257 ARG AAA CB  1 ? 
ATOM   1892 C  CG  . ARG A 1 257 ? -18.937 -2.176  62.714  1.000 124.931 ? 257 ARG AAA CG  1 ? 
ATOM   1893 C  CD  . ARG A 1 257 ? -17.847 -1.132  62.565  1.000 128.271 ? 257 ARG AAA CD  1 ? 
ATOM   1894 N  NE  . ARG A 1 257 ? -17.839 -0.217  63.701  1.000 136.617 ? 257 ARG AAA NE  1 ? 
ATOM   1895 C  CZ  . ARG A 1 257 ? -17.110 0.894   63.792  1.000 137.516 ? 257 ARG AAA CZ  1 ? 
ATOM   1896 N  NH1 . ARG A 1 257 ? -16.315 1.261   62.799  1.000 136.801 ? 257 ARG AAA NH1 1 ? 
ATOM   1897 N  NH2 . ARG A 1 257 ? -17.191 1.644   64.879  1.000 134.059 ? 257 ARG AAA NH2 1 ? 
ATOM   1898 N  N   . ALA A 1 258 ? -20.272 -3.011  59.156  1.000 123.051 ? 258 ALA AAA N   1 ? 
ATOM   1899 C  CA  . ALA A 1 258 ? -20.946 -2.269  58.079  1.000 124.609 ? 258 ALA AAA CA  1 ? 
ATOM   1900 C  C   . ALA A 1 258 ? -22.397 -2.724  57.993  1.000 118.525 ? 258 ALA AAA C   1 ? 
ATOM   1901 O  O   . ALA A 1 258 ? -23.313 -1.963  58.310  1.000 114.659 ? 258 ALA AAA O   1 ? 
ATOM   1902 C  CB  . ALA A 1 258 ? -20.223 -2.437  56.761  1.000 126.267 ? 258 ALA AAA CB  1 ? 
ATOM   1903 N  N   . ASP A 1 259 ? -22.587 -3.962  57.585  1.000 113.853 ? 259 ASP AAA N   1 ? 
ATOM   1904 C  CA  . ASP A 1 259 ? -23.941 -4.523  57.425  1.000 111.859 ? 259 ASP AAA CA  1 ? 
ATOM   1905 C  C   . ASP A 1 259 ? -24.830 -4.108  58.603  1.000 104.316 ? 259 ASP AAA C   1 ? 
ATOM   1906 O  O   . ASP A 1 259 ? -26.026 -3.815  58.404  1.000 99.318  ? 259 ASP AAA O   1 ? 
ATOM   1907 C  CB  . ASP A 1 259 ? -23.893 -6.044  57.252  1.000 116.229 ? 259 ASP AAA CB  1 ? 
ATOM   1908 C  CG  . ASP A 1 259 ? -23.085 -6.497  56.046  1.000 117.425 ? 259 ASP AAA CG  1 ? 
ATOM   1909 O  OD1 . ASP A 1 259 ? -22.696 -5.627  55.235  1.000 118.179 ? 259 ASP AAA OD1 1 ? 
ATOM   1910 O  OD2 . ASP A 1 259 ? -22.838 -7.714  55.934  1.000 116.559 ? 259 ASP AAA OD2 1 ? 
ATOM   1911 N  N   . LEU A 1 260 ? -24.278 -4.104  59.812  1.000 101.851 ? 260 LEU AAA N   1 ? 
ATOM   1912 C  CA  . LEU A 1 260 ? -25.066 -3.693  60.990  1.000 100.538 ? 260 LEU AAA CA  1 ? 
ATOM   1913 C  C   . LEU A 1 260 ? -25.414 -2.214  60.954  1.000 101.546 ? 260 LEU AAA C   1 ? 
ATOM   1914 O  O   . LEU A 1 260 ? -26.558 -1.826  61.249  1.000 101.174 ? 260 LEU AAA O   1 ? 
ATOM   1915 C  CB  . LEU A 1 260 ? -24.312 -4.043  62.277  1.000 99.867  ? 260 LEU AAA CB  1 ? 
ATOM   1916 C  CG  . LEU A 1 260 ? -24.925 -3.487  63.562  1.000 98.727  ? 260 LEU AAA CG  1 ? 
ATOM   1917 C  CD1 . LEU A 1 260 ? -26.381 -3.912  63.715  1.000 96.454  ? 260 LEU AAA CD1 1 ? 
ATOM   1918 C  CD2 . LEU A 1 260 ? -24.109 -3.920  64.771  1.000 100.756 ? 260 LEU AAA CD2 1 ? 
ATOM   1919 N  N   . ALA A 1 261 ? -24.420 -1.408  60.630  1.000 103.363 ? 261 ALA AAA N   1 ? 
ATOM   1920 C  CA  . ALA A 1 261 ? -24.606 0.046   60.539  1.000 104.372 ? 261 ALA AAA CA  1 ? 
ATOM   1921 C  C   . ALA A 1 261 ? -25.644 0.367   59.466  1.000 102.334 ? 261 ALA AAA C   1 ? 
ATOM   1922 O  O   . ALA A 1 261 ? -26.424 1.315   59.624  1.000 103.729 ? 261 ALA AAA O   1 ? 
ATOM   1923 C  CB  . ALA A 1 261 ? -23.288 0.726   60.257  1.000 107.667 ? 261 ALA AAA CB  1 ? 
ATOM   1924 N  N   . LYS A 1 262 ? -25.640 -0.420  58.397  1.000 99.253  ? 262 LYS AAA N   1 ? 
ATOM   1925 C  CA  . LYS A 1 262 ? -26.634 -0.297  57.323  1.000 99.944  ? 262 LYS AAA CA  1 ? 
ATOM   1926 C  C   . LYS A 1 262 ? -27.981 -0.736  57.852  1.000 97.576  ? 262 LYS AAA C   1 ? 
ATOM   1927 O  O   . LYS A 1 262 ? -28.965 -0.034  57.658  1.000 98.827  ? 262 LYS AAA O   1 ? 
ATOM   1928 C  CB  . LYS A 1 262 ? -26.227 -1.125  56.102  1.000 100.740 ? 262 LYS AAA CB  1 ? 
ATOM   1929 C  CG  . LYS A 1 262 ? -27.075 -0.879  54.861  1.000 100.988 ? 262 LYS AAA CG  1 ? 
ATOM   1930 C  CD  . LYS A 1 262 ? -26.917 -1.941  53.802  1.000 104.139 ? 262 LYS AAA CD  1 ? 
ATOM   1931 C  CE  . LYS A 1 262 ? -27.601 -3.242  54.166  1.000 111.316 ? 262 LYS AAA CE  1 ? 
ATOM   1932 N  NZ  . LYS A 1 262 ? -26.942 -4.404  53.525  1.000 117.995 ? 262 LYS AAA NZ  1 ? 
ATOM   1933 N  N   . TYR A 1 263 ? -28.035 -1.862  58.531  1.000 96.323  ? 263 TYR AAA N   1 ? 
ATOM   1934 C  CA  . TYR A 1 263 ? -29.316 -2.286  59.107  1.000 99.724  ? 263 TYR AAA CA  1 ? 
ATOM   1935 C  C   . TYR A 1 263 ? -29.894 -1.183  59.978  1.000 96.578  ? 263 TYR AAA C   1 ? 
ATOM   1936 O  O   . TYR A 1 263 ? -31.043 -0.777  59.789  1.000 97.530  ? 263 TYR AAA O   1 ? 
ATOM   1937 C  CB  . TYR A 1 263 ? -29.173 -3.574  59.923  1.000 111.318 ? 263 TYR AAA CB  1 ? 
ATOM   1938 C  CG  . TYR A 1 263 ? -30.441 -3.998  60.622  1.000 119.005 ? 263 TYR AAA CG  1 ? 
ATOM   1939 C  CD1 . TYR A 1 263 ? -31.323 -4.888  60.030  1.000 119.785 ? 263 TYR AAA CD1 1 ? 
ATOM   1940 C  CD2 . TYR A 1 263 ? -30.773 -3.492  61.870  1.000 127.331 ? 263 TYR AAA CD2 1 ? 
ATOM   1941 C  CE1 . TYR A 1 263 ? -32.493 -5.273  60.663  1.000 122.838 ? 263 TYR AAA CE1 1 ? 
ATOM   1942 C  CE2 . TYR A 1 263 ? -31.940 -3.865  62.517  1.000 127.591 ? 263 TYR AAA CE2 1 ? 
ATOM   1943 C  CZ  . TYR A 1 263 ? -32.803 -4.759  61.909  1.000 127.141 ? 263 TYR AAA CZ  1 ? 
ATOM   1944 O  OH  . TYR A 1 263 ? -33.955 -5.140  62.533  1.000 134.037 ? 263 TYR AAA OH  1 ? 
ATOM   1945 N  N   . ILE A 1 264 ? -29.131 -0.746  60.963  1.000 96.683  ? 264 ILE AAA N   1 ? 
ATOM   1946 C  CA  . ILE A 1 264 ? -29.703 0.170   61.977  1.000 100.586 ? 264 ILE AAA CA  1 ? 
ATOM   1947 C  C   . ILE A 1 264 ? -30.414 1.323   61.274  1.000 102.178 ? 264 ILE AAA C   1 ? 
ATOM   1948 O  O   . ILE A 1 264 ? -31.584 1.613   61.564  1.000 104.270 ? 264 ILE AAA O   1 ? 
ATOM   1949 C  CB  . ILE A 1 264 ? -28.621 0.647   62.969  1.000 104.985 ? 264 ILE AAA CB  1 ? 
ATOM   1950 C  CG1 . ILE A 1 264 ? -28.262 -0.464  63.963  1.000 108.650 ? 264 ILE AAA CG1 1 ? 
ATOM   1951 C  CG2 . ILE A 1 264 ? -29.057 1.924   63.677  1.000 107.561 ? 264 ILE AAA CG2 1 ? 
ATOM   1952 C  CD1 . ILE A 1 264 ? -27.380 -0.024  65.114  1.000 112.671 ? 264 ILE AAA CD1 1 ? 
ATOM   1953 N  N   . CYS A 1 265 ? -29.719 1.926   60.333  1.000 106.134 ? 265 CYS AAA N   1 ? 
ATOM   1954 C  CA  . CYS A 1 265 ? -30.162 3.158   59.669  1.000 111.147 ? 265 CYS AAA CA  1 ? 
ATOM   1955 C  C   . CYS A 1 265 ? -31.418 2.978   58.835  1.000 105.608 ? 265 CYS AAA C   1 ? 
ATOM   1956 O  O   . CYS A 1 265 ? -32.184 3.929   58.738  1.000 107.767 ? 265 CYS AAA O   1 ? 
ATOM   1957 C  CB  . CYS A 1 265 ? -29.056 3.696   58.774  1.000 123.464 ? 265 CYS AAA CB  1 ? 
ATOM   1958 S  SG  . CYS A 1 265 ? -27.768 4.524   59.736  1.000 150.220 ? 265 CYS AAA SG  1 ? 
ATOM   1959 N  N   . GLU A 1 266 ? -31.620 1.808   58.241  1.000 103.934 ? 266 GLU AAA N   1 ? 
ATOM   1960 C  CA  . GLU A 1 266 ? -32.849 1.539   57.462  1.000 106.378 ? 266 GLU AAA CA  1 ? 
ATOM   1961 C  C   . GLU A 1 266 ? -34.032 1.572   58.407  1.000 105.202 ? 266 GLU AAA C   1 ? 
ATOM   1962 O  O   . GLU A 1 266 ? -35.064 2.182   58.093  1.000 108.008 ? 266 GLU AAA O   1 ? 
ATOM   1963 C  CB  . GLU A 1 266 ? -32.792 0.164   56.794  1.000 112.465 ? 266 GLU AAA CB  1 ? 
ATOM   1964 C  CG  . GLU A 1 266 ? -31.741 0.055   55.706  1.000 120.907 ? 266 GLU AAA CG  1 ? 
ATOM   1965 C  CD  . GLU A 1 266 ? -31.191 -1.344  55.469  1.000 128.089 ? 266 GLU AAA CD  1 ? 
ATOM   1966 O  OE1 . GLU A 1 266 ? -30.892 -1.668  54.301  1.000 134.459 ? 266 GLU AAA OE1 1 ? 
ATOM   1967 O  OE2 . GLU A 1 266 ? -31.049 -2.105  56.450  1.000 132.070 ? 266 GLU AAA OE2 1 ? 
ATOM   1968 N  N   . ASN A 1 267 ? -33.854 0.967   59.565  1.000 108.185 ? 267 ASN AAA N   1 ? 
ATOM   1969 C  CA  . ASN A 1 267 ? -34.970 0.798   60.509  1.000 110.886 ? 267 ASN AAA CA  1 ? 
ATOM   1970 C  C   . ASN A 1 267 ? -35.023 1.871   61.593  1.000 111.340 ? 267 ASN AAA C   1 ? 
ATOM   1971 O  O   . ASN A 1 267 ? -35.890 1.808   62.491  1.000 106.890 ? 267 ASN AAA O   1 ? 
ATOM   1972 C  CB  . ASN A 1 267 ? -34.962 -0.642  61.028  1.000 116.549 ? 267 ASN AAA CB  1 ? 
ATOM   1973 C  CG  . ASN A 1 267 ? -34.865 -1.637  59.887  1.000 117.410 ? 267 ASN AAA CG  1 ? 
ATOM   1974 O  OD1 . ASN A 1 267 ? -33.788 -1.856  59.337  1.000 123.538 ? 267 ASN AAA OD1 1 ? 
ATOM   1975 N  ND2 . ASN A 1 267 ? -35.988 -2.220  59.497  1.000 112.015 ? 267 ASN AAA ND2 1 ? 
ATOM   1976 N  N   . GLN A 1 268 ? -34.113 2.829   61.517  1.000 117.926 ? 268 GLN AAA N   1 ? 
ATOM   1977 C  CA  . GLN A 1 268 ? -34.045 4.017   62.406  1.000 127.372 ? 268 GLN AAA CA  1 ? 
ATOM   1978 C  C   . GLN A 1 268 ? -35.304 4.333   63.221  1.000 131.612 ? 268 GLN AAA C   1 ? 
ATOM   1979 O  O   . GLN A 1 268 ? -35.216 4.434   64.459  1.000 128.912 ? 268 GLN AAA O   1 ? 
ATOM   1980 C  CB  . GLN A 1 268 ? -33.717 5.247   61.557  1.000 129.336 ? 268 GLN AAA CB  1 ? 
ATOM   1981 C  CG  . GLN A 1 268 ? -33.215 6.424   62.378  1.000 137.179 ? 268 GLN AAA CG  1 ? 
ATOM   1982 C  CD  . GLN A 1 268 ? -32.822 7.612   61.535  1.000 143.810 ? 268 GLN AAA CD  1 ? 
ATOM   1983 O  OE1 . GLN A 1 268 ? -32.844 8.753   61.994  1.000 153.159 ? 268 GLN AAA OE1 1 ? 
ATOM   1984 N  NE2 . GLN A 1 268 ? -32.460 7.359   60.287  1.000 141.897 ? 268 GLN AAA NE2 1 ? 
ATOM   1985 N  N   . ASP A 1 269 ? -36.434 4.557   62.560  1.000 141.680 ? 269 ASP AAA N   1 ? 
ATOM   1986 C  CA  . ASP A 1 269 ? -37.677 4.953   63.270  1.000 152.796 ? 269 ASP AAA CA  1 ? 
ATOM   1987 C  C   . ASP A 1 269 ? -37.957 4.078   64.496  1.000 162.045 ? 269 ASP AAA C   1 ? 
ATOM   1988 O  O   . ASP A 1 269 ? -38.362 4.596   65.569  1.000 175.921 ? 269 ASP AAA O   1 ? 
ATOM   1989 C  CB  . ASP A 1 269 ? -38.893 4.973   62.332  1.000 149.511 ? 269 ASP AAA CB  1 ? 
ATOM   1990 C  CG  . ASP A 1 269 ? -39.398 6.369   61.985  1.000 146.629 ? 269 ASP AAA CG  1 ? 
ATOM   1991 O  OD1 . ASP A 1 269 ? -39.904 7.058   62.898  1.000 139.514 ? 269 ASP AAA OD1 1 ? 
ATOM   1992 O  OD2 . ASP A 1 269 ? -39.290 6.756   60.802  1.000 142.254 ? 269 ASP AAA OD2 1 ? 
ATOM   1993 N  N   . SER A 1 270 ? -37.728 2.781   64.363  1.000 161.046 ? 270 SER AAA N   1 ? 
ATOM   1994 C  CA  . SER A 1 270 ? -38.005 1.810   65.439  1.000 155.035 ? 270 SER AAA CA  1 ? 
ATOM   1995 C  C   . SER A 1 270 ? -36.866 1.657   66.443  1.000 150.722 ? 270 SER AAA C   1 ? 
ATOM   1996 O  O   . SER A 1 270 ? -36.932 0.745   67.286  1.000 145.237 ? 270 SER AAA O   1 ? 
ATOM   1997 C  CB  . SER A 1 270 ? -38.367 0.472   64.831  1.000 148.939 ? 270 SER AAA CB  1 ? 
ATOM   1998 O  OG  . SER A 1 270 ? -37.412 0.077   63.856  1.000 136.921 ? 270 SER AAA OG  1 ? 
ATOM   1999 N  N   . ILE A 1 271 ? -35.856 2.520   66.397  1.000 142.727 ? 271 ILE AAA N   1 ? 
ATOM   2000 C  CA  . ILE A 1 271 ? -34.652 2.363   67.258  1.000 133.627 ? 271 ILE AAA CA  1 ? 
ATOM   2001 C  C   . ILE A 1 271 ? -34.384 3.633   68.079  1.000 131.243 ? 271 ILE AAA C   1 ? 
ATOM   2002 O  O   . ILE A 1 271 ? -34.365 3.584   69.323  1.000 133.089 ? 271 ILE AAA O   1 ? 
ATOM   2003 C  CB  . ILE A 1 271 ? -33.445 1.948   66.389  1.000 128.992 ? 271 ILE AAA CB  1 ? 
ATOM   2004 C  CG1 . ILE A 1 271 ? -33.686 0.582   65.735  1.000 120.651 ? 271 ILE AAA CG1 1 ? 
ATOM   2005 C  CG2 . ILE A 1 271 ? -32.148 1.975   67.191  1.000 131.177 ? 271 ILE AAA CG2 1 ? 
ATOM   2006 C  CD1 . ILE A 1 271 ? -32.756 0.260   64.591  1.000 119.633 ? 271 ILE AAA CD1 1 ? 
ATOM   2007 N  N   . SER A 1 272 ? -34.150 4.742   67.403  1.000 123.920 ? 272 SER AAA N   1 ? 
ATOM   2008 C  CA  . SER A 1 272 ? -33.847 6.001   68.088  1.000 121.180 ? 272 SER AAA CA  1 ? 
ATOM   2009 C  C   . SER A 1 272 ? -34.111 7.176   67.175  1.000 119.402 ? 272 SER AAA C   1 ? 
ATOM   2010 O  O   . SER A 1 272 ? -33.932 7.073   65.955  1.000 118.093 ? 272 SER AAA O   1 ? 
ATOM   2011 C  CB  . SER A 1 272 ? -32.421 6.002   68.599  1.000 119.519 ? 272 SER AAA CB  1 ? 
ATOM   2012 O  OG  . SER A 1 272 ? -32.178 7.095   69.476  1.000 114.070 ? 272 SER AAA OG  1 ? 
ATOM   2013 N  N   . SER A 1 273 ? -34.442 8.289   67.805  1.000 116.814 ? 273 SER AAA N   1 ? 
ATOM   2014 C  CA  . SER A 1 273 ? -34.633 9.602   67.158  1.000 118.005 ? 273 SER AAA CA  1 ? 
ATOM   2015 C  C   . SER A 1 273 ? -33.301 10.248  66.833  1.000 126.999 ? 273 SER AAA C   1 ? 
ATOM   2016 O  O   . SER A 1 273 ? -33.243 11.174  66.009  1.000 132.874 ? 273 SER AAA O   1 ? 
ATOM   2017 C  CB  . SER A 1 273 ? -35.458 10.492  68.043  1.000 114.909 ? 273 SER AAA CB  1 ? 
ATOM   2018 O  OG  . SER A 1 273 ? -36.411 9.725   68.762  1.000 113.818 ? 273 SER AAA OG  1 ? 
ATOM   2019 N  N   . LYS A 1 274 ? -32.246 9.767   67.466  1.000 141.753 ? 274 LYS AAA N   1 ? 
ATOM   2020 C  CA  . LYS A 1 274 ? -30.979 10.507  67.531  1.000 156.053 ? 274 LYS AAA CA  1 ? 
ATOM   2021 C  C   . LYS A 1 274 ? -30.118 10.197  66.316  1.000 159.951 ? 274 LYS AAA C   1 ? 
ATOM   2022 O  O   . LYS A 1 274 ? -29.197 10.983  65.988  1.000 152.998 ? 274 LYS AAA O   1 ? 
ATOM   2023 C  CB  . LYS A 1 274 ? -30.242 10.150  68.827  1.000 163.433 ? 274 LYS AAA CB  1 ? 
ATOM   2024 C  CG  . LYS A 1 274 ? -31.069 10.281  70.101  1.000 165.916 ? 274 LYS AAA CG  1 ? 
ATOM   2025 C  CD  . LYS A 1 274 ? -31.606 11.677  70.329  1.000 166.287 ? 274 LYS AAA CD  1 ? 
ATOM   2026 C  CE  . LYS A 1 274 ? -32.316 11.825  71.657  1.000 167.583 ? 274 LYS AAA CE  1 ? 
ATOM   2027 N  NZ  . LYS A 1 274 ? -32.615 13.244  71.956  1.000 168.195 ? 274 LYS AAA NZ  1 ? 
ATOM   2028 N  N   . LEU A 1 275 ? -30.425 9.094   65.644  1.000 168.106 ? 275 LEU AAA N   1 ? 
ATOM   2029 C  CA  . LEU A 1 275 ? -29.536 8.480   64.641  1.000 178.778 ? 275 LEU AAA CA  1 ? 
ATOM   2030 C  C   . LEU A 1 275 ? -29.390 9.317   63.360  1.000 183.896 ? 275 LEU AAA C   1 ? 
ATOM   2031 O  O   . LEU A 1 275 ? -28.357 9.199   62.705  1.000 198.561 ? 275 LEU AAA O   1 ? 
ATOM   2032 C  CB  . LEU A 1 275 ? -30.078 7.084   64.313  1.000 184.387 ? 275 LEU AAA CB  1 ? 
ATOM   2033 C  CG  . LEU A 1 275 ? -29.977 6.054   65.440  1.000 191.822 ? 275 LEU AAA CG  1 ? 
ATOM   2034 C  CD1 . LEU A 1 275 ? -30.970 4.919   65.245  1.000 187.554 ? 275 LEU AAA CD1 1 ? 
ATOM   2035 C  CD2 . LEU A 1 275 ? -28.562 5.507   65.554  1.000 201.030 ? 275 LEU AAA CD2 1 ? 
ATOM   2036 N  N   . LYS A 1 276 ? -30.397 10.123  63.009  1.000 180.890 ? 276 LYS AAA N   1 ? 
ATOM   2037 C  CA  . LYS A 1 276 ? -30.477 10.887  61.733  1.000 176.070 ? 276 LYS AAA CA  1 ? 
ATOM   2038 C  C   . LYS A 1 276 ? -29.126 11.452  61.304  1.000 172.886 ? 276 LYS AAA C   1 ? 
ATOM   2039 O  O   . LYS A 1 276 ? -28.612 11.081  60.228  1.000 171.894 ? 276 LYS AAA O   1 ? 
ATOM   2040 C  CB  . LYS A 1 276 ? -31.507 12.014  61.870  1.000 173.361 ? 276 LYS AAA CB  1 ? 
ATOM   2041 N  N   . GLU A 1 277 ? -28.563 12.339  62.107  1.000 167.547 ? 277 GLU AAA N   1 ? 
ATOM   2042 C  CA  . GLU A 1 277 ? -27.251 12.933  61.797  1.000 163.319 ? 277 GLU AAA CA  1 ? 
ATOM   2043 C  C   . GLU A 1 277 ? -26.272 11.813  61.454  1.000 164.975 ? 277 GLU AAA C   1 ? 
ATOM   2044 O  O   . GLU A 1 277 ? -25.695 11.789  60.348  1.000 170.140 ? 277 GLU AAA O   1 ? 
ATOM   2045 C  CB  . GLU A 1 277 ? -26.742 13.760  62.980  1.000 158.753 ? 277 GLU AAA CB  1 ? 
ATOM   2046 N  N   . CYS A 1 278 ? -26.128 10.856  62.360  1.000 164.185 ? 278 CYS AAA N   1 ? 
ATOM   2047 C  CA  . CYS A 1 278 ? -25.172 9.743   62.153  1.000 157.440 ? 278 CYS AAA CA  1 ? 
ATOM   2048 C  C   . CYS A 1 278 ? -25.409 9.033   60.815  1.000 151.077 ? 278 CYS AAA C   1 ? 
ATOM   2049 O  O   . CYS A 1 278 ? -24.464 8.886   60.028  1.000 142.737 ? 278 CYS AAA O   1 ? 
ATOM   2050 C  CB  . CYS A 1 278 ? -25.247 8.707   63.272  1.000 153.233 ? 278 CYS AAA CB  1 ? 
ATOM   2051 S  SG  . CYS A 1 278 ? -24.678 9.308   64.884  1.000 149.029 ? 278 CYS AAA SG  1 ? 
ATOM   2052 N  N   . CYS A 1 279 ? -26.649 8.622   60.562  1.000 150.712 ? 279 CYS AAA N   1 ? 
ATOM   2053 C  CA  . CYS A 1 279 ? -27.021 7.790   59.371  1.000 152.290 ? 279 CYS AAA CA  1 ? 
ATOM   2054 C  C   . CYS A 1 279 ? -26.751 8.458   58.023  1.000 150.782 ? 279 CYS AAA C   1 ? 
ATOM   2055 O  O   . CYS A 1 279 ? -26.688 7.749   56.967  1.000 151.996 ? 279 CYS AAA O   1 ? 
ATOM   2056 C  CB  . CYS A 1 279 ? -28.496 7.415   59.434  1.000 154.571 ? 279 CYS AAA CB  1 ? 
ATOM   2057 S  SG  . CYS A 1 279 ? -28.808 6.055   60.586  1.000 161.847 ? 279 CYS AAA SG  1 ? 
ATOM   2058 N  N   . GLU A 1 280 ? -26.644 9.779   58.047  1.000 155.947 ? 280 GLU AAA N   1 ? 
ATOM   2059 C  CA  . GLU A 1 280 ? -26.459 10.585  56.838  1.000 164.451 ? 280 GLU AAA CA  1 ? 
ATOM   2060 C  C   . GLU A 1 280 ? -25.027 10.480  56.318  1.000 164.551 ? 280 GLU AAA C   1 ? 
ATOM   2061 O  O   . GLU A 1 280 ? -24.816 10.772  55.138  1.000 165.714 ? 280 GLU AAA O   1 ? 
ATOM   2062 C  CB  . GLU A 1 280 ? -26.860 12.034  57.122  1.000 170.213 ? 280 GLU AAA CB  1 ? 
ATOM   2063 N  N   . LYS A 1 281 ? -24.077 10.025  57.136  1.000 160.886 ? 281 LYS AAA N   1 ? 
ATOM   2064 C  CA  . LYS A 1 281 ? -22.634 10.176  56.782  1.000 161.751 ? 281 LYS AAA CA  1 ? 
ATOM   2065 C  C   . LYS A 1 281 ? -21.985 8.881   56.259  1.000 160.764 ? 281 LYS AAA C   1 ? 
ATOM   2066 O  O   . LYS A 1 281 ? -22.596 7.807   56.210  1.000 161.111 ? 281 LYS AAA O   1 ? 
ATOM   2067 C  CB  . LYS A 1 281 ? -21.836 10.804  57.939  1.000 166.298 ? 281 LYS AAA CB  1 ? 
ATOM   2068 C  CG  . LYS A 1 281 ? -22.335 10.561  59.357  1.000 167.776 ? 281 LYS AAA CG  1 ? 
ATOM   2069 C  CD  . LYS A 1 281 ? -21.588 11.357  60.415  1.000 166.077 ? 281 LYS AAA CD  1 ? 
ATOM   2070 C  CE  . LYS A 1 281 ? -22.158 12.744  60.631  1.000 163.002 ? 281 LYS AAA CE  1 ? 
ATOM   2071 N  NZ  . LYS A 1 281 ? -21.661 13.355  61.886  1.000 163.241 ? 281 LYS AAA NZ  1 ? 
ATOM   2072 N  N   . PRO A 1 282 ? -20.726 8.975   55.755  1.000 162.179 ? 282 PRO AAA N   1 ? 
ATOM   2073 C  CA  . PRO A 1 282 ? -20.033 7.841   55.140  1.000 158.015 ? 282 PRO AAA CA  1 ? 
ATOM   2074 C  C   . PRO A 1 282 ? -19.715 6.659   56.040  1.000 149.350 ? 282 PRO AAA C   1 ? 
ATOM   2075 O  O   . PRO A 1 282 ? -19.685 6.763   57.280  1.000 142.737 ? 282 PRO AAA O   1 ? 
ATOM   2076 C  CB  . PRO A 1 282 ? -18.694 8.434   54.663  1.000 162.666 ? 282 PRO AAA CB  1 ? 
ATOM   2077 C  CG  . PRO A 1 282 ? -18.988 9.902   54.486  1.000 166.899 ? 282 PRO AAA CG  1 ? 
ATOM   2078 C  CD  . PRO A 1 282 ? -19.947 10.219  55.613  1.000 167.406 ? 282 PRO AAA CD  1 ? 
ATOM   2079 N  N   . LEU A 1 283 ? -19.416 5.568   55.356  1.000 142.492 ? 283 LEU AAA N   1 ? 
ATOM   2080 C  CA  . LEU A 1 283 ? -19.460 4.230   55.952  1.000 139.690 ? 283 LEU AAA CA  1 ? 
ATOM   2081 C  C   . LEU A 1 283 ? -18.731 4.269   57.277  1.000 134.578 ? 283 LEU AAA C   1 ? 
ATOM   2082 O  O   . LEU A 1 283 ? -19.312 3.905   58.307  1.000 135.702 ? 283 LEU AAA O   1 ? 
ATOM   2083 C  CB  . LEU A 1 283 ? -18.816 3.216   55.000  1.000 142.666 ? 283 LEU AAA CB  1 ? 
ATOM   2084 C  CG  . LEU A 1 283 ? -18.674 1.794   55.547  1.000 148.086 ? 283 LEU AAA CG  1 ? 
ATOM   2085 C  CD1 . LEU A 1 283 ? -19.985 1.289   56.143  1.000 145.781 ? 283 LEU AAA CD1 1 ? 
ATOM   2086 C  CD2 . LEU A 1 283 ? -18.185 0.844   54.464  1.000 150.074 ? 283 LEU AAA CD2 1 ? 
ATOM   2087 N  N   . LEU A 1 284 ? -17.506 4.759   57.237  1.000 129.204 ? 284 LEU AAA N   1 ? 
ATOM   2088 C  CA  . LEU A 1 284 ? -16.665 4.806   58.433  1.000 126.977 ? 284 LEU AAA CA  1 ? 
ATOM   2089 C  C   . LEU A 1 284 ? -17.235 5.747   59.487  1.000 116.911 ? 284 LEU AAA C   1 ? 
ATOM   2090 O  O   . LEU A 1 284 ? -17.350 5.334   60.653  1.000 108.858 ? 284 LEU AAA O   1 ? 
ATOM   2091 C  CB  . LEU A 1 284 ? -15.240 5.218   58.042  1.000 134.066 ? 284 LEU AAA CB  1 ? 
ATOM   2092 C  CG  . LEU A 1 284 ? -14.483 4.269   57.109  1.000 134.783 ? 284 LEU AAA CG  1 ? 
ATOM   2093 C  CD1 . LEU A 1 284 ? -13.060 4.765   56.892  1.000 137.129 ? 284 LEU AAA CD1 1 ? 
ATOM   2094 C  CD2 . LEU A 1 284 ? -14.465 2.843   57.645  1.000 132.426 ? 284 LEU AAA CD2 1 ? 
ATOM   2095 N  N   . GLU A 1 285 ? -17.562 6.974   59.104  1.000 109.089 ? 285 GLU AAA N   1 ? 
ATOM   2096 C  CA  . GLU A 1 285 ? -18.062 7.970   60.074  1.000 104.956 ? 285 GLU AAA CA  1 ? 
ATOM   2097 C  C   . GLU A 1 285 ? -19.247 7.350   60.792  1.000 103.608 ? 285 GLU AAA C   1 ? 
ATOM   2098 O  O   . GLU A 1 285 ? -19.277 7.292   62.024  1.000 109.353 ? 285 GLU AAA O   1 ? 
ATOM   2099 C  CB  . GLU A 1 285 ? -18.479 9.271   59.379  1.000 99.882  ? 285 GLU AAA CB  1 ? 
ATOM   2100 C  CG  . GLU A 1 285 ? -17.331 10.229  59.112  1.000 98.382  ? 285 GLU AAA CG  1 ? 
ATOM   2101 C  CD  . GLU A 1 285 ? -16.410 9.839   57.964  1.000 98.327  ? 285 GLU AAA CD  1 ? 
ATOM   2102 O  OE1 . GLU A 1 285 ? -16.738 10.157  56.804  1.000 97.870  ? 285 GLU AAA OE1 1 ? 
ATOM   2103 O  OE2 . GLU A 1 285 ? -15.365 9.214   58.227  1.000 95.867  ? 285 GLU AAA OE2 1 ? 
ATOM   2104 N  N   . LYS A 1 286 ? -20.216 6.881   60.035  1.000 99.194  ? 286 LYS AAA N   1 ? 
ATOM   2105 C  CA  . LYS A 1 286 ? -21.491 6.552   60.689  1.000 101.486 ? 286 LYS AAA CA  1 ? 
ATOM   2106 C  C   . LYS A 1 286 ? -21.313 5.423   61.701  1.000 98.800  ? 286 LYS AAA C   1 ? 
ATOM   2107 O  O   . LYS A 1 286 ? -21.916 5.495   62.757  1.000 97.977  ? 286 LYS AAA O   1 ? 
ATOM   2108 C  CB  . LYS A 1 286 ? -22.623 6.380   59.668  1.000 106.824 ? 286 LYS AAA CB  1 ? 
ATOM   2109 C  CG  . LYS A 1 286 ? -22.704 5.094   58.858  1.000 107.063 ? 286 LYS AAA CG  1 ? 
ATOM   2110 C  CD  . LYS A 1 286 ? -24.067 4.986   58.173  1.000 107.476 ? 286 LYS AAA CD  1 ? 
ATOM   2111 C  CE  . LYS A 1 286 ? -24.065 4.246   56.851  1.000 107.059 ? 286 LYS AAA CE  1 ? 
ATOM   2112 N  NZ  . LYS A 1 286 ? -25.387 4.321   56.183  1.000 105.243 ? 286 LYS AAA NZ  1 ? 
ATOM   2113 N  N   . SER A 1 287 ? -20.473 4.441   61.437  1.000 97.859  ? 287 SER AAA N   1 ? 
ATOM   2114 C  CA  . SER A 1 287 ? -20.308 3.310   62.372  1.000 101.881 ? 287 SER AAA CA  1 ? 
ATOM   2115 C  C   . SER A 1 287 ? -19.813 3.819   63.723  1.000 106.265 ? 287 SER AAA C   1 ? 
ATOM   2116 O  O   . SER A 1 287 ? -20.217 3.293   64.781  1.000 108.847 ? 287 SER AAA O   1 ? 
ATOM   2117 C  CB  . SER A 1 287 ? -19.373 2.271   61.798  1.000 99.301  ? 287 SER AAA CB  1 ? 
ATOM   2118 O  OG  . SER A 1 287 ? -19.902 1.697   60.610  1.000 92.981  ? 287 SER AAA OG  1 ? 
ATOM   2119 N  N   . HIS A 1 288 ? -18.947 4.823   63.670  1.000 108.243 ? 288 HIS AAA N   1 ? 
ATOM   2120 C  CA  . HIS A 1 288 ? -18.397 5.453   64.882  1.000 112.817 ? 288 HIS AAA CA  1 ? 
ATOM   2121 C  C   . HIS A 1 288 ? -19.504 6.286   65.509  1.000 115.727 ? 288 HIS AAA C   1 ? 
ATOM   2122 O  O   . HIS A 1 288 ? -19.900 6.076   66.664  1.000 121.235 ? 288 HIS AAA O   1 ? 
ATOM   2123 C  CB  . HIS A 1 288 ? -17.162 6.303   64.529  1.000 113.212 ? 288 HIS AAA CB  1 ? 
ATOM   2124 C  CG  . HIS A 1 288 ? -16.670 7.193   65.627  1.000 121.893 ? 288 HIS AAA CG  1 ? 
ATOM   2125 N  ND1 . HIS A 1 288 ? -15.588 6.859   66.422  1.000 129.773 ? 288 HIS AAA ND1 1 ? 
ATOM   2126 C  CD2 . HIS A 1 288 ? -17.083 8.412   66.049  1.000 124.872 ? 288 HIS AAA CD2 1 ? 
ATOM   2127 C  CE1 . HIS A 1 288 ? -15.366 7.827   67.292  1.000 132.475 ? 288 HIS AAA CE1 1 ? 
ATOM   2128 N  NE2 . HIS A 1 288 ? -16.271 8.796   67.085  1.000 124.804 ? 288 HIS AAA NE2 1 ? 
ATOM   2129 N  N   . CYS A 1 289 ? -20.028 7.201   64.716  1.000 119.760 ? 289 CYS AAA N   1 ? 
ATOM   2130 C  CA  . CYS A 1 289 ? -21.119 8.081   65.153  1.000 124.788 ? 289 CYS AAA CA  1 ? 
ATOM   2131 C  C   . CYS A 1 289 ? -22.115 7.265   65.974  1.000 120.905 ? 289 CYS AAA C   1 ? 
ATOM   2132 O  O   . CYS A 1 289 ? -22.327 7.553   67.156  1.000 121.604 ? 289 CYS AAA O   1 ? 
ATOM   2133 C  CB  . CYS A 1 289 ? -21.827 8.749   63.980  1.000 132.074 ? 289 CYS AAA CB  1 ? 
ATOM   2134 S  SG  . CYS A 1 289 ? -22.865 10.142  64.497  1.000 146.931 ? 289 CYS AAA SG  1 ? 
ATOM   2135 N  N   . ILE A 1 290 ? -22.662 6.228   65.348  1.000 116.289 ? 290 ILE AAA N   1 ? 
ATOM   2136 C  CA  . ILE A 1 290 ? -23.701 5.353   65.948  1.000 113.726 ? 290 ILE AAA CA  1 ? 
ATOM   2137 C  C   . ILE A 1 290 ? -23.181 4.828   67.271  1.000 115.024 ? 290 ILE AAA C   1 ? 
ATOM   2138 O  O   . ILE A 1 290 ? -23.871 4.936   68.293  1.000 109.721 ? 290 ILE AAA O   1 ? 
ATOM   2139 C  CB  . ILE A 1 290 ? -24.098 4.195   65.006  1.000 108.869 ? 290 ILE AAA CB  1 ? 
ATOM   2140 C  CG1 . ILE A 1 290 ? -24.842 4.694   63.765  1.000 105.165 ? 290 ILE AAA CG1 1 ? 
ATOM   2141 C  CG2 . ILE A 1 290 ? -24.917 3.148   65.751  1.000 107.547 ? 290 ILE AAA CG2 1 ? 
ATOM   2142 C  CD1 . ILE A 1 290 ? -24.898 3.684   62.642  1.000 103.337 ? 290 ILE AAA CD1 1 ? 
ATOM   2143 N  N   . ALA A 1 291 ? -21.975 4.284   67.235  1.000 120.681 ? 291 ALA AAA N   1 ? 
ATOM   2144 C  CA  . ALA A 1 291 ? -21.374 3.682   68.424  1.000 130.143 ? 291 ALA AAA CA  1 ? 
ATOM   2145 C  C   . ALA A 1 291 ? -21.458 4.690   69.553  1.000 134.973 ? 291 ALA AAA C   1 ? 
ATOM   2146 O  O   . ALA A 1 291 ? -21.730 4.297   70.688  1.000 140.024 ? 291 ALA AAA O   1 ? 
ATOM   2147 C  CB  . ALA A 1 291 ? -19.949 3.260   68.147  1.000 133.425 ? 291 ALA AAA CB  1 ? 
ATOM   2148 N  N   . GLU A 1 292 ? -21.276 5.956   69.194  1.000 140.961 ? 292 GLU AAA N   1 ? 
ATOM   2149 C  CA  . GLU A 1 292 ? -21.136 7.066   70.152  1.000 144.681 ? 292 GLU AAA CA  1 ? 
ATOM   2150 C  C   . GLU A 1 292 ? -22.437 7.821   70.466  1.000 142.356 ? 292 GLU AAA C   1 ? 
ATOM   2151 O  O   . GLU A 1 292 ? -22.438 8.636   71.414  1.000 143.334 ? 292 GLU AAA O   1 ? 
ATOM   2152 C  CB  . GLU A 1 292 ? -20.081 8.056   69.643  1.000 149.826 ? 292 GLU AAA CB  1 ? 
ATOM   2153 C  CG  . GLU A 1 292 ? -18.727 7.432   69.320  1.000 157.498 ? 292 GLU AAA CG  1 ? 
ATOM   2154 C  CD  . GLU A 1 292 ? -17.911 6.906   70.493  1.000 161.855 ? 292 GLU AAA CD  1 ? 
ATOM   2155 O  OE1 . GLU A 1 292 ? -17.786 7.630   71.501  1.000 163.322 ? 292 GLU AAA OE1 1 ? 
ATOM   2156 O  OE2 . GLU A 1 292 ? -17.379 5.776   70.387  1.000 164.031 ? 292 GLU AAA OE2 1 ? 
ATOM   2157 N  N   . VAL A 1 293 ? -23.520 7.594   69.724  1.000 140.499 ? 293 VAL AAA N   1 ? 
ATOM   2158 C  CA  . VAL A 1 293 ? -24.796 8.348   69.949  1.000 139.926 ? 293 VAL AAA CA  1 ? 
ATOM   2159 C  C   . VAL A 1 293 ? -25.164 8.572   71.425  1.000 150.904 ? 293 VAL AAA C   1 ? 
ATOM   2160 O  O   . VAL A 1 293 ? -24.818 7.765   72.330  1.000 174.019 ? 293 VAL AAA O   1 ? 
ATOM   2161 C  CB  . VAL A 1 293 ? -26.001 7.694   69.244  1.000 132.189 ? 293 VAL AAA CB  1 ? 
ATOM   2162 C  CG1 . VAL A 1 293 ? -25.928 7.849   67.737  1.000 128.701 ? 293 VAL AAA CG1 1 ? 
ATOM   2163 C  CG2 . VAL A 1 293 ? -26.193 6.239   69.645  1.000 136.421 ? 293 VAL AAA CG2 1 ? 
ATOM   2164 N  N   . GLU A 1 294 ? -25.940 9.632   71.622  1.000 145.569 ? 294 GLU AAA N   1 ? 
ATOM   2165 C  CA  . GLU A 1 294 ? -26.582 9.940   72.911  1.000 138.605 ? 294 GLU AAA CA  1 ? 
ATOM   2166 C  C   . GLU A 1 294 ? -27.765 9.001   73.123  1.000 132.735 ? 294 GLU AAA C   1 ? 
ATOM   2167 O  O   . GLU A 1 294 ? -28.336 8.468   72.151  1.000 127.227 ? 294 GLU AAA O   1 ? 
ATOM   2168 C  CB  . GLU A 1 294 ? -27.032 11.402  72.957  1.000 133.418 ? 294 GLU AAA CB  1 ? 
ATOM   2169 N  N   . ASN A 1 295 ? -28.115 8.799   74.379  1.000 126.689 ? 295 ASN AAA N   1 ? 
ATOM   2170 C  CA  . ASN A 1 295 ? -29.291 7.977   74.745  1.000 128.938 ? 295 ASN AAA CA  1 ? 
ATOM   2171 C  C   . ASN A 1 295 ? -30.573 8.624   74.220  1.000 125.647 ? 295 ASN AAA C   1 ? 
ATOM   2172 O  O   . ASN A 1 295 ? -30.730 9.844   74.343  1.000 122.214 ? 295 ASN AAA O   1 ? 
ATOM   2173 C  CB  . ASN A 1 295 ? -29.433 7.845   76.265  1.000 135.352 ? 295 ASN AAA CB  1 ? 
ATOM   2174 C  CG  . ASN A 1 295 ? -28.231 7.229   76.950  1.000 139.406 ? 295 ASN AAA CG  1 ? 
ATOM   2175 O  OD1 . ASN A 1 295 ? -27.455 6.506   76.330  1.000 145.912 ? 295 ASN AAA OD1 1 ? 
ATOM   2176 N  ND2 . ASN A 1 295 ? -28.073 7.513   78.233  1.000 138.278 ? 295 ASN AAA ND2 1 ? 
ATOM   2177 N  N   . ASP A 1 296 ? -31.494 7.829   73.691  1.000 127.634 ? 296 ASP AAA N   1 ? 
ATOM   2178 C  CA  . ASP A 1 296 ? -32.771 8.422   73.244  1.000 131.700 ? 296 ASP AAA CA  1 ? 
ATOM   2179 C  C   . ASP A 1 296 ? -33.570 8.865   74.464  1.000 130.359 ? 296 ASP AAA C   1 ? 
ATOM   2180 O  O   . ASP A 1 296 ? -33.312 8.396   75.574  1.000 133.559 ? 296 ASP AAA O   1 ? 
ATOM   2181 C  CB  . ASP A 1 296 ? -33.593 7.479   72.364  1.000 141.066 ? 296 ASP AAA CB  1 ? 
ATOM   2182 C  CG  . ASP A 1 296 ? -34.617 8.211   71.508  1.000 152.457 ? 296 ASP AAA CG  1 ? 
ATOM   2183 O  OD1 . ASP A 1 296 ? -35.081 9.292   71.934  1.000 150.418 ? 296 ASP AAA OD1 1 ? 
ATOM   2184 O  OD2 . ASP A 1 296 ? -34.940 7.704   70.419  1.000 170.547 ? 296 ASP AAA OD2 1 ? 
ATOM   2185 N  N   . GLU A 1 297 ? -34.524 9.754   74.247  1.000 131.867 ? 297 GLU AAA N   1 ? 
ATOM   2186 C  CA  . GLU A 1 297 ? -35.388 10.301  75.319  1.000 137.233 ? 297 GLU AAA CA  1 ? 
ATOM   2187 C  C   . GLU A 1 297 ? -36.231 9.198   75.997  1.000 139.340 ? 297 GLU AAA C   1 ? 
ATOM   2188 O  O   . GLU A 1 297 ? -36.846 8.387   75.273  1.000 138.875 ? 297 GLU AAA O   1 ? 
ATOM   2189 C  CB  . GLU A 1 297 ? -36.306 11.380  74.740  1.000 135.137 ? 297 GLU AAA CB  1 ? 
ATOM   2190 N  N   . MET A 1 298 ? -36.313 9.199   77.341  1.000 142.804 ? 298 MET AAA N   1 ? 
ATOM   2191 C  CA  . MET A 1 298 ? -37.012 8.159   78.180  1.000 146.765 ? 298 MET AAA CA  1 ? 
ATOM   2192 C  C   . MET A 1 298 ? -38.521 8.104   77.904  1.000 148.263 ? 298 MET AAA C   1 ? 
ATOM   2193 O  O   . MET A 1 298 ? -39.231 9.047   78.245  1.000 157.757 ? 298 MET AAA O   1 ? 
ATOM   2194 C  CB  . MET A 1 298 ? -36.789 8.465   79.669  1.000 145.972 ? 298 MET AAA CB  1 ? 
ATOM   2195 C  CG  . MET A 1 298 ? -37.299 7.392   80.620  1.000 146.086 ? 298 MET AAA CG  1 ? 
ATOM   2196 S  SD  . MET A 1 298 ? -37.426 7.997   82.329  1.000 147.253 ? 298 MET AAA SD  1 ? 
ATOM   2197 C  CE  . MET A 1 298 ? -35.799 7.576   82.956  1.000 156.552 ? 298 MET AAA CE  1 ? 
ATOM   2198 N  N   . PRO A 1 299 ? -39.071 6.996   77.339  1.000 145.497 ? 299 PRO AAA N   1 ? 
ATOM   2199 C  CA  . PRO A 1 299 ? -40.496 6.985   76.987  1.000 148.407 ? 299 PRO AAA CA  1 ? 
ATOM   2200 C  C   . PRO A 1 299 ? -41.403 7.328   78.162  1.000 152.432 ? 299 PRO AAA C   1 ? 
ATOM   2201 O  O   . PRO A 1 299 ? -41.018 7.150   79.301  1.000 156.417 ? 299 PRO AAA O   1 ? 
ATOM   2202 C  CB  . PRO A 1 299 ? -40.791 5.551   76.517  1.000 145.792 ? 299 PRO AAA CB  1 ? 
ATOM   2203 C  CG  . PRO A 1 299 ? -39.434 4.896   76.309  1.000 143.436 ? 299 PRO AAA CG  1 ? 
ATOM   2204 C  CD  . PRO A 1 299 ? -38.417 5.706   77.090  1.000 144.256 ? 299 PRO AAA CD  1 ? 
ATOM   2205 N  N   . ALA A 1 300 ? -42.613 7.779   77.852  1.000 150.226 ? 300 ALA AAA N   1 ? 
ATOM   2206 C  CA  . ALA A 1 300 ? -43.475 8.435   78.842  1.000 155.765 ? 300 ALA AAA CA  1 ? 
ATOM   2207 C  C   . ALA A 1 300 ? -43.939 7.458   79.922  1.000 164.670 ? 300 ALA AAA C   1 ? 
ATOM   2208 O  O   . ALA A 1 300 ? -43.263 7.307   80.967  1.000 173.954 ? 300 ALA AAA O   1 ? 
ATOM   2209 C  CB  . ALA A 1 300 ? -44.634 9.102   78.138  1.000 155.563 ? 300 ALA AAA CB  1 ? 
ATOM   2210 N  N   . ASP A 1 301 ? -45.092 6.849   79.715  1.000 170.715 ? 301 ASP AAA N   1 ? 
ATOM   2211 C  CA  . ASP A 1 301 ? -45.748 6.088   80.793  1.000 172.241 ? 301 ASP AAA CA  1 ? 
ATOM   2212 C  C   . ASP A 1 301 ? -45.430 4.624   80.590  1.000 161.707 ? 301 ASP AAA C   1 ? 
ATOM   2213 O  O   . ASP A 1 301 ? -46.095 3.966   79.772  1.000 150.916 ? 301 ASP AAA O   1 ? 
ATOM   2214 C  CB  . ASP A 1 301 ? -47.255 6.365   80.830  1.000 179.627 ? 301 ASP AAA CB  1 ? 
ATOM   2215 C  CG  . ASP A 1 301 ? -47.621 7.842   80.869  1.000 180.621 ? 301 ASP AAA CG  1 ? 
ATOM   2216 O  OD1 . ASP A 1 301 ? -46.698 8.678   80.966  1.000 177.799 ? 301 ASP AAA OD1 1 ? 
ATOM   2217 O  OD2 . ASP A 1 301 ? -48.830 8.146   80.794  1.000 181.457 ? 301 ASP AAA OD2 1 ? 
ATOM   2218 N  N   . LEU A 1 302 ? -44.432 4.159   81.326  1.000 158.547 ? 302 LEU AAA N   1 ? 
ATOM   2219 C  CA  . LEU A 1 302 ? -43.970 2.774   81.233  1.000 161.707 ? 302 LEU AAA CA  1 ? 
ATOM   2220 C  C   . LEU A 1 302 ? -44.397 2.075   82.503  1.000 150.742 ? 302 LEU AAA C   1 ? 
ATOM   2221 O  O   . LEU A 1 302 ? -43.988 2.454   83.598  1.000 146.857 ? 302 LEU AAA O   1 ? 
ATOM   2222 C  CB  . LEU A 1 302 ? -42.446 2.732   81.072  1.000 177.163 ? 302 LEU AAA CB  1 ? 
ATOM   2223 C  CG  . LEU A 1 302 ? -41.894 3.233   79.738  1.000 188.609 ? 302 LEU AAA CG  1 ? 
ATOM   2224 C  CD1 . LEU A 1 302 ? -40.372 3.277   79.773  1.000 198.000 ? 302 LEU AAA CD1 1 ? 
ATOM   2225 C  CD2 . LEU A 1 302 ? -42.375 2.370   78.580  1.000 186.256 ? 302 LEU AAA CD2 1 ? 
ATOM   2226 N  N   . PRO A 1 303 ? -45.216 1.022   82.370  1.000 140.213 ? 303 PRO AAA N   1 ? 
ATOM   2227 C  CA  . PRO A 1 303 ? -45.741 0.372   83.558  1.000 136.275 ? 303 PRO AAA CA  1 ? 
ATOM   2228 C  C   . PRO A 1 303 ? -44.584 0.006   84.479  1.000 133.359 ? 303 PRO AAA C   1 ? 
ATOM   2229 O  O   . PRO A 1 303 ? -43.624 -0.576  84.017  1.000 135.362 ? 303 PRO AAA O   1 ? 
ATOM   2230 C  CB  . PRO A 1 303 ? -46.458 -0.874  83.017  1.000 135.097 ? 303 PRO AAA CB  1 ? 
ATOM   2231 C  CG  . PRO A 1 303 ? -45.864 -1.086  81.637  1.000 134.425 ? 303 PRO AAA CG  1 ? 
ATOM   2232 C  CD  . PRO A 1 303 ? -45.548 0.305   81.130  1.000 136.493 ? 303 PRO AAA CD  1 ? 
ATOM   2233 N  N   . SER A 1 304 ? -44.692 0.382   85.747  1.000 132.215 ? 304 SER AAA N   1 ? 
ATOM   2234 C  CA  . SER A 1 304 ? -43.687 0.033   86.765  1.000 131.112 ? 304 SER AAA CA  1 ? 
ATOM   2235 C  C   . SER A 1 304 ? -43.270 -1.412  86.563  1.000 133.394 ? 304 SER AAA C   1 ? 
ATOM   2236 O  O   . SER A 1 304 ? -44.107 -2.248  86.189  1.000 131.872 ? 304 SER AAA O   1 ? 
ATOM   2237 C  CB  . SER A 1 304 ? -44.221 0.254   88.160  1.000 129.919 ? 304 SER AAA CB  1 ? 
ATOM   2238 O  OG  . SER A 1 304 ? -45.466 -0.413  88.343  1.000 124.256 ? 304 SER AAA OG  1 ? 
ATOM   2239 N  N   . LEU A 1 305 ? -42.010 -1.699  86.833  1.000 131.096 ? 305 LEU AAA N   1 ? 
ATOM   2240 C  CA  . LEU A 1 305 ? -41.494 -3.074  86.699  1.000 124.254 ? 305 LEU AAA CA  1 ? 
ATOM   2241 C  C   . LEU A 1 305 ? -42.300 -4.023  87.572  1.000 119.478 ? 305 LEU AAA C   1 ? 
ATOM   2242 O  O   . LEU A 1 305 ? -42.955 -4.946  87.038  1.000 116.631 ? 305 LEU AAA O   1 ? 
ATOM   2243 C  CB  . LEU A 1 305 ? -40.010 -3.101  87.081  1.000 123.750 ? 305 LEU AAA CB  1 ? 
ATOM   2244 C  CG  . LEU A 1 305 ? -39.063 -2.434  86.085  1.000 123.834 ? 305 LEU AAA CG  1 ? 
ATOM   2245 C  CD1 . LEU A 1 305 ? -37.785 -1.983  86.773  1.000 125.438 ? 305 LEU AAA CD1 1 ? 
ATOM   2246 C  CD2 . LEU A 1 305 ? -38.746 -3.365  84.925  1.000 120.567 ? 305 LEU AAA CD2 1 ? 
ATOM   2247 N  N   . ALA A 1 306 ? -42.280 -3.770  88.874  1.000 112.377 ? 306 ALA AAA N   1 ? 
ATOM   2248 C  CA  . ALA A 1 306 ? -42.834 -4.650  89.921  1.000 102.517 ? 306 ALA AAA CA  1 ? 
ATOM   2249 C  C   . ALA A 1 306 ? -44.022 -5.478  89.435  1.000 97.153  ? 306 ALA AAA C   1 ? 
ATOM   2250 O  O   . ALA A 1 306 ? -44.124 -6.646  89.773  1.000 90.251  ? 306 ALA AAA O   1 ? 
ATOM   2251 C  CB  . ALA A 1 306 ? -43.215 -3.824  91.128  1.000 99.536  ? 306 ALA AAA CB  1 ? 
ATOM   2252 N  N   . ALA A 1 307 ? -44.939 -4.872  88.702  1.000 97.971  ? 307 ALA AAA N   1 ? 
ATOM   2253 C  CA  . ALA A 1 307 ? -46.137 -5.578  88.199  1.000 100.183 ? 307 ALA AAA CA  1 ? 
ATOM   2254 C  C   . ALA A 1 307 ? -45.796 -6.959  87.627  1.000 97.897  ? 307 ALA AAA C   1 ? 
ATOM   2255 O  O   . ALA A 1 307 ? -46.380 -7.985  88.023  1.000 95.469  ? 307 ALA AAA O   1 ? 
ATOM   2256 C  CB  . ALA A 1 307 ? -46.810 -4.727  87.150  1.000 102.060 ? 307 ALA AAA CB  1 ? 
ATOM   2257 N  N   . ASP A 1 308 ? -44.848 -6.974  86.699  1.000 99.751  ? 308 ASP AAA N   1 ? 
ATOM   2258 C  CA  . ASP A 1 308 ? -44.548 -8.165  85.884  1.000 103.956 ? 308 ASP AAA CA  1 ? 
ATOM   2259 C  C   . ASP A 1 308 ? -43.377 -8.957  86.433  1.000 95.233  ? 308 ASP AAA C   1 ? 
ATOM   2260 O  O   . ASP A 1 308 ? -43.199 -10.113 86.019  1.000 86.703  ? 308 ASP AAA O   1 ? 
ATOM   2261 C  CB  . ASP A 1 308 ? -44.315 -7.785  84.414  1.000 112.759 ? 308 ASP AAA CB  1 ? 
ATOM   2262 C  CG  . ASP A 1 308 ? -45.584 -7.627  83.584  1.000 117.258 ? 308 ASP AAA CG  1 ? 
ATOM   2263 O  OD1 . ASP A 1 308 ? -45.489 -7.731  82.338  1.000 114.165 ? 308 ASP AAA OD1 1 ? 
ATOM   2264 O  OD2 . ASP A 1 308 ? -46.659 -7.399  84.181  1.000 123.166 ? 308 ASP AAA OD2 1 ? 
ATOM   2265 N  N   . PHE A 1 309 ? -42.624 -8.386  87.362  1.000 91.816  ? 309 PHE AAA N   1 ? 
ATOM   2266 C  CA  . PHE A 1 309 ? -41.425 -9.063  87.877  1.000 93.279  ? 309 PHE AAA CA  1 ? 
ATOM   2267 C  C   . PHE A 1 309 ? -41.447 -9.296  89.384  1.000 96.310  ? 309 PHE AAA C   1 ? 
ATOM   2268 O  O   . PHE A 1 309 ? -40.486 -9.870  89.894  1.000 100.427 ? 309 PHE AAA O   1 ? 
ATOM   2269 C  CB  . PHE A 1 309 ? -40.181 -8.279  87.454  1.000 97.089  ? 309 PHE AAA CB  1 ? 
ATOM   2270 C  CG  . PHE A 1 309 ? -39.950 -8.249  85.963  1.000 99.980  ? 309 PHE AAA CG  1 ? 
ATOM   2271 C  CD1 . PHE A 1 309 ? -39.562 -9.392  85.281  1.000 100.396 ? 309 PHE AAA CD1 1 ? 
ATOM   2272 C  CD2 . PHE A 1 309 ? -40.110 -7.077  85.240  1.000 103.055 ? 309 PHE AAA CD2 1 ? 
ATOM   2273 C  CE1 . PHE A 1 309 ? -39.345 -9.364  83.911  1.000 100.078 ? 309 PHE AAA CE1 1 ? 
ATOM   2274 C  CE2 . PHE A 1 309 ? -39.891 -7.051  83.871  1.000 102.857 ? 309 PHE AAA CE2 1 ? 
ATOM   2275 C  CZ  . PHE A 1 309 ? -39.512 -8.195  83.208  1.000 100.507 ? 309 PHE AAA CZ  1 ? 
ATOM   2276 N  N   . VAL A 1 310 ? -42.526 -8.912  90.072  1.000 99.898  ? 310 VAL AAA N   1 ? 
ATOM   2277 C  CA  . VAL A 1 310 ? -42.685 -9.098  91.549  1.000 101.153 ? 310 VAL AAA CA  1 ? 
ATOM   2278 C  C   . VAL A 1 310 ? -44.130 -9.440  91.939  1.000 99.045  ? 310 VAL AAA C   1 ? 
ATOM   2279 O  O   . VAL A 1 310 ? -44.386 -10.458 92.600  1.000 96.011  ? 310 VAL AAA O   1 ? 
ATOM   2280 C  CB  . VAL A 1 310 ? -42.211 -7.861  92.341  1.000 106.261 ? 310 VAL AAA CB  1 ? 
ATOM   2281 C  CG1 . VAL A 1 310 ? -42.248 -8.107  93.844  1.000 106.319 ? 310 VAL AAA CG1 1 ? 
ATOM   2282 C  CG2 . VAL A 1 310 ? -40.823 -7.400  91.925  1.000 110.013 ? 310 VAL AAA CG2 1 ? 
ATOM   2283 N  N   . GLU A 1 311 ? -45.070 -8.607  91.521  1.000 98.624  ? 311 GLU AAA N   1 ? 
ATOM   2284 C  CA  . GLU A 1 311 ? -46.503 -8.823  91.811  1.000 97.869  ? 311 GLU AAA CA  1 ? 
ATOM   2285 C  C   . GLU A 1 311 ? -47.061 -9.988  90.982  1.000 92.606  ? 311 GLU AAA C   1 ? 
ATOM   2286 O  O   . GLU A 1 311 ? -47.949 -10.711 91.484  1.000 88.917  ? 311 GLU AAA O   1 ? 
ATOM   2287 C  CB  . GLU A 1 311 ? -47.283 -7.535  91.531  1.000 102.098 ? 311 GLU AAA CB  1 ? 
ATOM   2288 C  CG  . GLU A 1 311 ? -46.938 -6.392  92.475  1.000 106.625 ? 311 GLU AAA CG  1 ? 
ATOM   2289 C  CD  . GLU A 1 311 ? -47.190 -4.992  91.930  1.000 109.884 ? 311 GLU AAA CD  1 ? 
ATOM   2290 O  OE1 . GLU A 1 311 ? -48.337 -4.711  91.515  1.000 107.279 ? 311 GLU AAA OE1 1 ? 
ATOM   2291 O  OE2 . GLU A 1 311 ? -46.236 -4.182  91.919  1.000 112.520 ? 311 GLU AAA OE2 1 ? 
ATOM   2292 N  N   . SER A 1 312 ? -46.589 -10.186 89.755  1.000 90.173  ? 312 SER AAA N   1 ? 
ATOM   2293 C  CA  . SER A 1 312 ? -47.124 -11.265 88.880  1.000 89.389  ? 312 SER AAA CA  1 ? 
ATOM   2294 C  C   . SER A 1 312 ? -47.158 -12.615 89.585  1.000 93.236  ? 312 SER AAA C   1 ? 
ATOM   2295 O  O   . SER A 1 312 ? -46.282 -12.916 90.412  1.000 97.774  ? 312 SER AAA O   1 ? 
ATOM   2296 C  CB  . SER A 1 312 ? -46.346 -11.352 87.590  1.000 86.659  ? 312 SER AAA CB  1 ? 
ATOM   2297 O  OG  . SER A 1 312 ? -46.908 -12.327 86.726  1.000 84.331  ? 312 SER AAA OG  1 ? 
ATOM   2298 N  N   . LYS A 1 313 ? -48.140 -13.424 89.216  1.000 95.810  ? 313 LYS AAA N   1 ? 
ATOM   2299 C  CA  . LYS A 1 313 ? -48.254 -14.806 89.721  1.000 98.221  ? 313 LYS AAA CA  1 ? 
ATOM   2300 C  C   . LYS A 1 313 ? -47.429 -15.758 88.858  1.000 99.517  ? 313 LYS AAA C   1 ? 
ATOM   2301 O  O   . LYS A 1 313 ? -47.195 -16.909 89.283  1.000 106.574 ? 313 LYS AAA O   1 ? 
ATOM   2302 C  CB  . LYS A 1 313 ? -49.724 -15.237 89.754  1.000 100.442 ? 313 LYS AAA CB  1 ? 
ATOM   2303 N  N   . ASP A 1 314 ? -46.955 -15.289 87.702  1.000 98.398  ? 314 ASP AAA N   1 ? 
ATOM   2304 C  CA  . ASP A 1 314 ? -46.243 -16.142 86.716  1.000 101.028 ? 314 ASP AAA CA  1 ? 
ATOM   2305 C  C   . ASP A 1 314 ? -44.745 -15.877 86.642  1.000 106.609 ? 314 ASP AAA C   1 ? 
ATOM   2306 O  O   . ASP A 1 314 ? -44.105 -16.248 85.636  1.000 114.697 ? 314 ASP AAA O   1 ? 
ATOM   2307 C  CB  . ASP A 1 314 ? -46.805 -15.944 85.306  1.000 97.991  ? 314 ASP AAA CB  1 ? 
ATOM   2308 C  CG  . ASP A 1 314 ? -48.283 -16.245 85.186  1.000 95.980  ? 314 ASP AAA CG  1 ? 
ATOM   2309 O  OD1 . ASP A 1 314 ? -49.048 -15.737 86.025  1.000 98.830  ? 314 ASP AAA OD1 1 ? 
ATOM   2310 O  OD2 . ASP A 1 314 ? -48.648 -16.990 84.258  1.000 92.995  ? 314 ASP AAA OD2 1 ? 
ATOM   2311 N  N   . VAL A 1 315 ? -44.189 -15.270 87.677  1.000 105.337 ? 315 VAL AAA N   1 ? 
ATOM   2312 C  CA  . VAL A 1 315 ? -42.727 -15.048 87.746  1.000 100.846 ? 315 VAL AAA CA  1 ? 
ATOM   2313 C  C   . VAL A 1 315 ? -42.045 -16.408 87.760  1.000 96.786  ? 315 VAL AAA C   1 ? 
ATOM   2314 O  O   . VAL A 1 315 ? -41.317 -16.785 86.798  1.000 95.925  ? 315 VAL AAA O   1 ? 
ATOM   2315 C  CB  . VAL A 1 315 ? -42.337 -14.214 88.985  1.000 103.691 ? 315 VAL AAA CB  1 ? 
ATOM   2316 C  CG1 . VAL A 1 315 ? -40.828 -14.072 89.130  1.000 102.987 ? 315 VAL AAA CG1 1 ? 
ATOM   2317 C  CG2 . VAL A 1 315 ? -42.999 -12.844 88.984  1.000 107.133 ? 315 VAL AAA CG2 1 ? 
ATOM   2318 N  N   . CYS A 1 316 ? -42.336 -17.141 88.823  1.000 96.504  ? 316 CYS AAA N   1 ? 
ATOM   2319 C  CA  . CYS A 1 316 ? -41.805 -18.486 89.050  1.000 101.484 ? 316 CYS AAA CA  1 ? 
ATOM   2320 C  C   . CYS A 1 316 ? -42.092 -19.412 87.876  1.000 105.075 ? 316 CYS AAA C   1 ? 
ATOM   2321 O  O   . CYS A 1 316 ? -41.311 -20.352 87.683  1.000 106.883 ? 316 CYS AAA O   1 ? 
ATOM   2322 C  CB  . CYS A 1 316 ? -42.376 -19.093 90.325  1.000 106.661 ? 316 CYS AAA CB  1 ? 
ATOM   2323 S  SG  . CYS A 1 316 ? -41.492 -18.569 91.815  1.000 121.715 ? 316 CYS AAA SG  1 ? 
ATOM   2324 N  N   . LYS A 1 317 ? -43.165 -19.166 87.122  1.000 115.907 ? 317 LYS AAA N   1 ? 
ATOM   2325 C  CA  . LYS A 1 317 ? -43.439 -19.915 85.871  1.000 127.374 ? 317 LYS AAA CA  1 ? 
ATOM   2326 C  C   . LYS A 1 317 ? -42.518 -19.494 84.733  1.000 121.769 ? 317 LYS AAA C   1 ? 
ATOM   2327 O  O   . LYS A 1 317 ? -41.790 -20.327 84.173  1.000 131.413 ? 317 LYS AAA O   1 ? 
ATOM   2328 C  CB  . LYS A 1 317 ? -44.900 -19.744 85.440  1.000 139.328 ? 317 LYS AAA CB  1 ? 
ATOM   2329 C  CG  . LYS A 1 317 ? -45.264 -20.428 84.127  1.000 147.614 ? 317 LYS AAA CG  1 ? 
ATOM   2330 C  CD  . LYS A 1 317 ? -46.609 -20.008 83.579  1.000 157.458 ? 317 LYS AAA CD  1 ? 
ATOM   2331 C  CE  . LYS A 1 317 ? -46.690 -20.098 82.070  1.000 161.480 ? 317 LYS AAA CE  1 ? 
ATOM   2332 N  NZ  . LYS A 1 317 ? -47.740 -19.202 81.532  1.000 164.425 ? 317 LYS AAA NZ  1 ? 
ATOM   2333 N  N   . ASN A 1 318 ? -42.567 -18.223 84.375  1.000 112.026 ? 318 ASN AAA N   1 ? 
ATOM   2334 C  CA  . ASN A 1 318 ? -41.745 -17.716 83.252  1.000 106.431 ? 318 ASN AAA CA  1 ? 
ATOM   2335 C  C   . ASN A 1 318 ? -40.245 -17.951 83.463  1.000 106.207 ? 318 ASN AAA C   1 ? 
ATOM   2336 O  O   . ASN A 1 318 ? -39.501 -18.144 82.470  1.000 102.732 ? 318 ASN AAA O   1 ? 
ATOM   2337 C  CB  . ASN A 1 318 ? -42.008 -16.224 83.024  1.000 106.441 ? 318 ASN AAA CB  1 ? 
ATOM   2338 C  CG  . ASN A 1 318 ? -43.473 -15.900 82.818  1.000 107.113 ? 318 ASN AAA CG  1 ? 
ATOM   2339 O  OD1 . ASN A 1 318 ? -44.230 -16.731 82.320  1.000 114.168 ? 318 ASN AAA OD1 1 ? 
ATOM   2340 N  ND2 . ASN A 1 318 ? -43.884 -14.703 83.210  1.000 99.419  ? 318 ASN AAA ND2 1 ? 
ATOM   2341 N  N   . TYR A 1 319 ? -39.789 -17.907 84.714  1.000 110.782 ? 319 TYR AAA N   1 ? 
ATOM   2342 C  CA  . TYR A 1 319 ? -38.361 -18.174 85.017  1.000 113.772 ? 319 TYR AAA CA  1 ? 
ATOM   2343 C  C   . TYR A 1 319 ? -38.023 -19.628 84.769  1.000 109.318 ? 319 TYR AAA C   1 ? 
ATOM   2344 O  O   . TYR A 1 319 ? -36.861 -19.962 84.587  1.000 108.349 ? 319 TYR AAA O   1 ? 
ATOM   2345 C  CB  . TYR A 1 319 ? -38.025 -17.784 86.461  1.000 119.973 ? 319 TYR AAA CB  1 ? 
ATOM   2346 C  CG  . TYR A 1 319 ? -36.609 -18.088 86.885  1.000 123.506 ? 319 TYR AAA CG  1 ? 
ATOM   2347 C  CD1 . TYR A 1 319 ? -35.528 -17.505 86.243  1.000 123.717 ? 319 TYR AAA CD1 1 ? 
ATOM   2348 C  CD2 . TYR A 1 319 ? -36.346 -18.966 87.924  1.000 130.393 ? 319 TYR AAA CD2 1 ? 
ATOM   2349 C  CE1 . TYR A 1 319 ? -34.224 -17.786 86.618  1.000 125.380 ? 319 TYR AAA CE1 1 ? 
ATOM   2350 C  CE2 . TYR A 1 319 ? -35.047 -19.254 88.315  1.000 134.662 ? 319 TYR AAA CE2 1 ? 
ATOM   2351 C  CZ  . TYR A 1 319 ? -33.981 -18.662 87.660  1.000 130.014 ? 319 TYR AAA CZ  1 ? 
ATOM   2352 O  OH  . TYR A 1 319 ? -32.695 -18.932 88.032  1.000 125.161 ? 319 TYR AAA OH  1 ? 
ATOM   2353 N  N   . ALA A 1 320 ? -39.036 -20.474 84.799  1.000 110.301 ? 320 ALA AAA N   1 ? 
ATOM   2354 C  CA  . ALA A 1 320 ? -38.870 -21.892 84.465  1.000 112.509 ? 320 ALA AAA CA  1 ? 
ATOM   2355 C  C   . ALA A 1 320 ? -38.969 -22.087 82.960  1.000 114.162 ? 320 ALA AAA C   1 ? 
ATOM   2356 O  O   . ALA A 1 320 ? -38.074 -22.688 82.346  1.000 105.099 ? 320 ALA AAA O   1 ? 
ATOM   2357 C  CB  . ALA A 1 320 ? -39.891 -22.728 85.202  1.000 112.698 ? 320 ALA AAA CB  1 ? 
ATOM   2358 N  N   . GLU A 1 321 ? -40.048 -21.590 82.375  1.000 128.005 ? 321 GLU AAA N   1 ? 
ATOM   2359 C  CA  . GLU A 1 321 ? -40.322 -21.804 80.946  1.000 137.556 ? 321 GLU AAA CA  1 ? 
ATOM   2360 C  C   . GLU A 1 321 ? -39.307 -21.086 80.064  1.000 136.381 ? 321 GLU AAA C   1 ? 
ATOM   2361 O  O   . GLU A 1 321 ? -39.118 -21.553 78.933  1.000 137.115 ? 321 GLU AAA O   1 ? 
ATOM   2362 C  CB  . GLU A 1 321 ? -41.763 -21.401 80.617  1.000 150.159 ? 321 GLU AAA CB  1 ? 
ATOM   2363 C  CG  . GLU A 1 321 ? -42.809 -22.293 81.274  1.000 160.065 ? 321 GLU AAA CG  1 ? 
ATOM   2364 C  CD  . GLU A 1 321 ? -42.635 -23.791 81.055  1.000 170.086 ? 321 GLU AAA CD  1 ? 
ATOM   2365 O  OE1 . GLU A 1 321 ? -42.194 -24.187 79.957  1.000 184.265 ? 321 GLU AAA OE1 1 ? 
ATOM   2366 O  OE2 . GLU A 1 321 ? -42.950 -24.565 81.982  1.000 171.634 ? 321 GLU AAA OE2 1 ? 
ATOM   2367 N  N   . ALA A 1 322 ? -38.681 -20.002 80.533  1.000 136.903 ? 322 ALA AAA N   1 ? 
ATOM   2368 C  CA  . ALA A 1 322 ? -37.637 -19.321 79.726  1.000 138.211 ? 322 ALA AAA CA  1 ? 
ATOM   2369 C  C   . ALA A 1 322 ? -36.778 -18.329 80.525  1.000 138.218 ? 322 ALA AAA C   1 ? 
ATOM   2370 O  O   . ALA A 1 322 ? -36.850 -17.099 80.278  1.000 138.870 ? 322 ALA AAA O   1 ? 
ATOM   2371 C  CB  . ALA A 1 322 ? -38.285 -18.628 78.548  1.000 139.715 ? 322 ALA AAA CB  1 ? 
ATOM   2372 N  N   . LYS A 1 323 ? -35.948 -18.846 81.426  1.000 136.315 ? 323 LYS AAA N   1 ? 
ATOM   2373 C  CA  . LYS A 1 323 ? -35.162 -17.985 82.343  1.000 134.038 ? 323 LYS AAA CA  1 ? 
ATOM   2374 C  C   . LYS A 1 323 ? -34.425 -16.910 81.555  1.000 124.103 ? 323 LYS AAA C   1 ? 
ATOM   2375 O  O   . LYS A 1 323 ? -34.470 -15.752 81.949  1.000 123.528 ? 323 LYS AAA O   1 ? 
ATOM   2376 C  CB  . LYS A 1 323 ? -34.167 -18.797 83.179  1.000 140.572 ? 323 LYS AAA CB  1 ? 
ATOM   2377 C  CG  . LYS A 1 323 ? -33.142 -19.597 82.388  1.000 155.810 ? 323 LYS AAA CG  1 ? 
ATOM   2378 C  CD  . LYS A 1 323 ? -31.974 -20.093 83.212  1.000 171.804 ? 323 LYS AAA CD  1 ? 
ATOM   2379 C  CE  . LYS A 1 323 ? -30.859 -20.648 82.348  1.000 181.382 ? 323 LYS AAA CE  1 ? 
ATOM   2380 N  NZ  . LYS A 1 323 ? -29.746 -21.209 83.152  1.000 183.030 ? 323 LYS AAA NZ  1 ? 
ATOM   2381 N  N   . ASP A 1 324 ? -33.816 -17.277 80.438  1.000 121.601 ? 324 ASP AAA N   1 ? 
ATOM   2382 C  CA  . ASP A 1 324 ? -33.023 -16.325 79.636  1.000 124.111 ? 324 ASP AAA CA  1 ? 
ATOM   2383 C  C   . ASP A 1 324 ? -33.883 -15.189 79.108  1.000 113.830 ? 324 ASP AAA C   1 ? 
ATOM   2384 O  O   . ASP A 1 324 ? -33.567 -14.021 79.335  1.000 109.679 ? 324 ASP AAA O   1 ? 
ATOM   2385 C  CB  . ASP A 1 324 ? -32.353 -17.001 78.437  1.000 133.693 ? 324 ASP AAA CB  1 ? 
ATOM   2386 C  CG  . ASP A 1 324 ? -30.972 -17.557 78.727  1.000 141.817 ? 324 ASP AAA CG  1 ? 
ATOM   2387 O  OD1 . ASP A 1 324 ? -30.658 -18.635 78.189  1.000 150.080 ? 324 ASP AAA OD1 1 ? 
ATOM   2388 O  OD2 . ASP A 1 324 ? -30.216 -16.897 79.473  1.000 148.808 ? 324 ASP AAA OD2 1 ? 
ATOM   2389 N  N   . VAL A 1 325 ? -34.946 -15.552 78.409  1.000 106.347 ? 325 VAL AAA N   1 ? 
ATOM   2390 C  CA  . VAL A 1 325 ? -35.854 -14.575 77.767  1.000 103.143 ? 325 VAL AAA CA  1 ? 
ATOM   2391 C  C   . VAL A 1 325 ? -36.484 -13.707 78.836  1.000 97.492  ? 325 VAL AAA C   1 ? 
ATOM   2392 O  O   . VAL A 1 325 ? -36.684 -12.504 78.637  1.000 98.747  ? 325 VAL AAA O   1 ? 
ATOM   2393 C  CB  . VAL A 1 325 ? -36.918 -15.274 76.900  1.000 110.221 ? 325 VAL AAA CB  1 ? 
ATOM   2394 C  CG1 . VAL A 1 325 ? -38.007 -14.314 76.442  1.000 114.757 ? 325 VAL AAA CG1 1 ? 
ATOM   2395 C  CG2 . VAL A 1 325 ? -36.287 -15.973 75.705  1.000 112.080 ? 325 VAL AAA CG2 1 ? 
ATOM   2396 N  N   . PHE A 1 326 ? -36.783 -14.316 79.959  1.000 92.415  ? 326 PHE AAA N   1 ? 
ATOM   2397 C  CA  . PHE A 1 326 ? -37.429 -13.595 81.059  1.000 92.501  ? 326 PHE AAA CA  1 ? 
ATOM   2398 C  C   . PHE A 1 326 ? -36.489 -12.592 81.701  1.000 94.127  ? 326 PHE AAA C   1 ? 
ATOM   2399 O  O   . PHE A 1 326 ? -36.822 -11.408 81.835  1.000 93.430  ? 326 PHE AAA O   1 ? 
ATOM   2400 C  CB  . PHE A 1 326 ? -37.908 -14.612 82.093  1.000 92.208  ? 326 PHE AAA CB  1 ? 
ATOM   2401 C  CG  . PHE A 1 326 ? -38.754 -14.014 83.181  1.000 96.378  ? 326 PHE AAA CG  1 ? 
ATOM   2402 C  CD1 . PHE A 1 326 ? -38.328 -14.006 84.500  1.000 94.370  ? 326 PHE AAA CD1 1 ? 
ATOM   2403 C  CD2 . PHE A 1 326 ? -39.971 -13.431 82.867  1.000 108.007 ? 326 PHE AAA CD2 1 ? 
ATOM   2404 C  CE1 . PHE A 1 326 ? -39.119 -13.444 85.489  1.000 100.131 ? 326 PHE AAA CE1 1 ? 
ATOM   2405 C  CE2 . PHE A 1 326 ? -40.760 -12.869 83.856  1.000 113.577 ? 326 PHE AAA CE2 1 ? 
ATOM   2406 C  CZ  . PHE A 1 326 ? -40.333 -12.877 85.165  1.000 109.896 ? 326 PHE AAA CZ  1 ? 
ATOM   2407 N  N   . LEU A 1 327 ? -35.331 -13.093 82.109  1.000 96.460  ? 327 LEU AAA N   1 ? 
ATOM   2408 C  CA  . LEU A 1 327 ? -34.298 -12.262 82.759  1.000 93.248  ? 327 LEU AAA CA  1 ? 
ATOM   2409 C  C   . LEU A 1 327 ? -33.851 -11.186 81.781  1.000 85.610  ? 327 LEU AAA C   1 ? 
ATOM   2410 O  O   . LEU A 1 327 ? -33.461 -10.110 82.226  1.000 83.899  ? 327 LEU AAA O   1 ? 
ATOM   2411 C  CB  . LEU A 1 327 ? -33.087 -13.105 83.167  1.000 98.594  ? 327 LEU AAA CB  1 ? 
ATOM   2412 C  CG  . LEU A 1 327 ? -33.329 -14.153 84.249  1.000 106.536 ? 327 LEU AAA CG  1 ? 
ATOM   2413 C  CD1 . LEU A 1 327 ? -32.230 -15.206 84.224  1.000 111.925 ? 327 LEU AAA CD1 1 ? 
ATOM   2414 C  CD2 . LEU A 1 327 ? -33.434 -13.502 85.618  1.000 106.512 ? 327 LEU AAA CD2 1 ? 
ATOM   2415 N  N   . GLY A 1 328 ? -33.905 -11.490 80.480  1.000 78.196  ? 328 GLY AAA N   1 ? 
ATOM   2416 C  CA  . GLY A 1 328 ? -33.542 -10.533 79.425  1.000 71.365  ? 328 GLY AAA CA  1 ? 
ATOM   2417 C  C   . GLY A 1 328 ? -34.590 -9.464  79.316  1.000 64.901  ? 328 GLY AAA C   1 ? 
ATOM   2418 O  O   . GLY A 1 328 ? -34.285 -8.279  79.355  1.000 62.439  ? 328 GLY AAA O   1 ? 
ATOM   2419 N  N   . MET A 1 329 ? -35.828 -9.901  79.203  1.000 64.648  ? 329 MET AAA N   1 ? 
ATOM   2420 C  CA  . MET A 1 329 ? -36.973 -8.983  79.251  1.000 70.155  ? 329 MET AAA CA  1 ? 
ATOM   2421 C  C   . MET A 1 329 ? -36.826 -8.075  80.466  1.000 69.165  ? 329 MET AAA C   1 ? 
ATOM   2422 O  O   . MET A 1 329 ? -37.047 -6.873  80.352  1.000 73.734  ? 329 MET AAA O   1 ? 
ATOM   2423 C  CB  . MET A 1 329 ? -38.310 -9.741  79.300  1.000 73.805  ? 329 MET AAA CB  1 ? 
ATOM   2424 C  CG  . MET A 1 329 ? -38.756 -10.295 77.935  1.000 74.163  ? 329 MET AAA CG  1 ? 
ATOM   2425 S  SD  . MET A 1 329 ? -40.521 -10.739 77.789  1.000 68.562  ? 329 MET AAA SD  1 ? 
ATOM   2426 C  CE  . MET A 1 329 ? -40.509 -11.497 76.164  1.000 65.989  ? 329 MET AAA CE  1 ? 
ATOM   2427 N  N   . PHE A 1 330 ? -36.425 -8.645  81.593  1.000 65.713  ? 330 PHE AAA N   1 ? 
ATOM   2428 C  CA  . PHE A 1 330 ? -36.159 -7.862  82.811  1.000 65.623  ? 330 PHE AAA CA  1 ? 
ATOM   2429 C  C   . PHE A 1 330 ? -35.018 -6.857  82.641  1.000 67.272  ? 330 PHE AAA C   1 ? 
ATOM   2430 O  O   . PHE A 1 330 ? -35.202 -5.662  82.928  1.000 66.707  ? 330 PHE AAA O   1 ? 
ATOM   2431 C  CB  . PHE A 1 330 ? -35.823 -8.763  84.000  1.000 64.644  ? 330 PHE AAA CB  1 ? 
ATOM   2432 C  CG  . PHE A 1 330 ? -35.462 -8.006  85.254  1.000 62.209  ? 330 PHE AAA CG  1 ? 
ATOM   2433 C  CD1 . PHE A 1 330 ? -36.448 -7.548  86.113  1.000 60.569  ? 330 PHE AAA CD1 1 ? 
ATOM   2434 C  CD2 . PHE A 1 330 ? -34.139 -7.742  85.570  1.000 60.995  ? 330 PHE AAA CD2 1 ? 
ATOM   2435 C  CE1 . PHE A 1 330 ? -36.122 -6.859  87.270  1.000 59.336  ? 330 PHE AAA CE1 1 ? 
ATOM   2436 C  CE2 . PHE A 1 330 ? -33.814 -7.047  86.724  1.000 60.545  ? 330 PHE AAA CE2 1 ? 
ATOM   2437 C  CZ  . PHE A 1 330 ? -34.806 -6.609  87.573  1.000 59.892  ? 330 PHE AAA CZ  1 ? 
ATOM   2438 N  N   . LEU A 1 331 ? -33.846 -7.335  82.223  1.000 72.102  ? 331 LEU AAA N   1 ? 
ATOM   2439 C  CA  . LEU A 1 331 ? -32.644 -6.474  82.149  1.000 76.744  ? 331 LEU AAA CA  1 ? 
ATOM   2440 C  C   . LEU A 1 331 ? -32.997 -5.329  81.239  1.000 78.459  ? 331 LEU AAA C   1 ? 
ATOM   2441 O  O   . LEU A 1 331 ? -32.785 -4.191  81.596  1.000 80.585  ? 331 LEU AAA O   1 ? 
ATOM   2442 C  CB  . LEU A 1 331 ? -31.419 -7.252  81.647  1.000 81.122  ? 331 LEU AAA CB  1 ? 
ATOM   2443 C  CG  . LEU A 1 331 ? -30.125 -6.440  81.494  1.000 82.733  ? 331 LEU AAA CG  1 ? 
ATOM   2444 C  CD1 . LEU A 1 331 ? -29.780 -5.690  82.772  1.000 84.644  ? 331 LEU AAA CD1 1 ? 
ATOM   2445 C  CD2 . LEU A 1 331 ? -28.956 -7.324  81.082  1.000 82.246  ? 331 LEU AAA CD2 1 ? 
ATOM   2446 N  N   . TYR A 1 332 ? -33.573 -5.683  80.112  1.000 79.593  ? 332 TYR AAA N   1 ? 
ATOM   2447 C  CA  . TYR A 1 332 ? -34.090 -4.714  79.151  1.000 77.287  ? 332 TYR AAA CA  1 ? 
ATOM   2448 C  C   . TYR A 1 332 ? -34.956 -3.693  79.869  1.000 78.520  ? 332 TYR AAA C   1 ? 
ATOM   2449 O  O   . TYR A 1 332 ? -34.627 -2.490  79.903  1.000 79.651  ? 332 TYR AAA O   1 ? 
ATOM   2450 C  CB  . TYR A 1 332 ? -34.869 -5.459  78.064  1.000 75.411  ? 332 TYR AAA CB  1 ? 
ATOM   2451 C  CG  . TYR A 1 332 ? -35.801 -4.623  77.227  1.000 74.642  ? 332 TYR AAA CG  1 ? 
ATOM   2452 C  CD1 . TYR A 1 332 ? -35.315 -3.706  76.310  1.000 76.058  ? 332 TYR AAA CD1 1 ? 
ATOM   2453 C  CD2 . TYR A 1 332 ? -37.174 -4.778  77.319  1.000 74.985  ? 332 TYR AAA CD2 1 ? 
ATOM   2454 C  CE1 . TYR A 1 332 ? -36.167 -2.947  75.524  1.000 77.457  ? 332 TYR AAA CE1 1 ? 
ATOM   2455 C  CE2 . TYR A 1 332 ? -38.042 -4.028  76.541  1.000 76.211  ? 332 TYR AAA CE2 1 ? 
ATOM   2456 C  CZ  . TYR A 1 332 ? -37.539 -3.107  75.639  1.000 77.360  ? 332 TYR AAA CZ  1 ? 
ATOM   2457 O  OH  . TYR A 1 332 ? -38.396 -2.366  74.875  1.000 75.725  ? 332 TYR AAA OH  1 ? 
ATOM   2458 N  N   . GLU A 1 333 ? -36.028 -4.181  80.480  1.000 80.829  ? 333 GLU AAA N   1 ? 
ATOM   2459 C  CA  . GLU A 1 333 ? -37.049 -3.286  81.069  1.000 87.477  ? 333 GLU AAA CA  1 ? 
ATOM   2460 C  C   . GLU A 1 333 ? -36.451 -2.386  82.147  1.000 88.098  ? 333 GLU AAA C   1 ? 
ATOM   2461 O  O   . GLU A 1 333 ? -36.884 -1.230  82.273  1.000 95.732  ? 333 GLU AAA O   1 ? 
ATOM   2462 C  CB  . GLU A 1 333 ? -38.215 -4.094  81.635  1.000 97.888  ? 333 GLU AAA CB  1 ? 
ATOM   2463 C  CG  . GLU A 1 333 ? -39.100 -4.696  80.561  1.000 111.557 ? 333 GLU AAA CG  1 ? 
ATOM   2464 C  CD  . GLU A 1 333 ? -40.082 -3.739  79.906  1.000 124.195 ? 333 GLU AAA CD  1 ? 
ATOM   2465 O  OE1 . GLU A 1 333 ? -39.908 -2.514  80.066  1.000 128.273 ? 333 GLU AAA OE1 1 ? 
ATOM   2466 O  OE2 . GLU A 1 333 ? -41.019 -4.226  79.230  1.000 140.034 ? 333 GLU AAA OE2 1 ? 
ATOM   2467 N  N   . TYR A 1 334 ? -35.474 -2.875  82.905  1.000 85.854  ? 334 TYR AAA N   1 ? 
ATOM   2468 C  CA  . TYR A 1 334 ? -34.881 -2.060  83.986  1.000 81.165  ? 334 TYR AAA CA  1 ? 
ATOM   2469 C  C   . TYR A 1 334 ? -33.880 -1.068  83.403  1.000 79.674  ? 334 TYR AAA C   1 ? 
ATOM   2470 O  O   . TYR A 1 334 ? -33.889 0.125   83.765  1.000 77.867  ? 334 TYR AAA O   1 ? 
ATOM   2471 C  CB  . TYR A 1 334 ? -34.242 -2.935  85.065  1.000 82.355  ? 334 TYR AAA CB  1 ? 
ATOM   2472 C  CG  . TYR A 1 334 ? -34.266 -2.334  86.447  1.000 84.416  ? 334 TYR AAA CG  1 ? 
ATOM   2473 C  CD1 . TYR A 1 334 ? -33.680 -1.107  86.714  1.000 83.760  ? 334 TYR AAA CD1 1 ? 
ATOM   2474 C  CD2 . TYR A 1 334 ? -34.861 -3.007  87.504  1.000 89.889  ? 334 TYR AAA CD2 1 ? 
ATOM   2475 C  CE1 . TYR A 1 334 ? -33.693 -0.563  87.989  1.000 89.094  ? 334 TYR AAA CE1 1 ? 
ATOM   2476 C  CE2 . TYR A 1 334 ? -34.885 -2.476  88.784  1.000 91.600  ? 334 TYR AAA CE2 1 ? 
ATOM   2477 C  CZ  . TYR A 1 334 ? -34.297 -1.248  89.029  1.000 91.862  ? 334 TYR AAA CZ  1 ? 
ATOM   2478 O  OH  . TYR A 1 334 ? -34.316 -0.720  90.289  1.000 92.067  ? 334 TYR AAA OH  1 ? 
ATOM   2479 N  N   . ALA A 1 335 ? -33.029 -1.561  82.511  1.000 82.322  ? 335 ALA AAA N   1 ? 
ATOM   2480 C  CA  . ALA A 1 335 ? -32.018 -0.756  81.801  1.000 86.325  ? 335 ALA AAA CA  1 ? 
ATOM   2481 C  C   . ALA A 1 335 ? -32.688 0.405   81.080  1.000 88.829  ? 335 ALA AAA C   1 ? 
ATOM   2482 O  O   . ALA A 1 335 ? -32.293 1.555   81.309  1.000 97.151  ? 335 ALA AAA O   1 ? 
ATOM   2483 C  CB  . ALA A 1 335 ? -31.246 -1.625  80.840  1.000 88.118  ? 335 ALA AAA CB  1 ? 
ATOM   2484 N  N   . ARG A 1 336 ? -33.704 0.140   80.261  1.000 91.663  ? 336 ARG AAA N   1 ? 
ATOM   2485 C  CA  . ARG A 1 336 ? -34.365 1.243   79.504  1.000 99.839  ? 336 ARG AAA CA  1 ? 
ATOM   2486 C  C   . ARG A 1 336 ? -34.879 2.393   80.380  1.000 102.189 ? 336 ARG AAA C   1 ? 
ATOM   2487 O  O   . ARG A 1 336 ? -34.941 3.555   79.903  1.000 106.147 ? 336 ARG AAA O   1 ? 
ATOM   2488 C  CB  . ARG A 1 336 ? -35.476 0.721   78.589  1.000 104.917 ? 336 ARG AAA CB  1 ? 
ATOM   2489 C  CG  . ARG A 1 336 ? -36.638 0.042   79.294  1.000 109.885 ? 336 ARG AAA CG  1 ? 
ATOM   2490 C  CD  . ARG A 1 336 ? -37.377 -0.864  78.326  1.000 113.769 ? 336 ARG AAA CD  1 ? 
ATOM   2491 N  NE  . ARG A 1 336 ? -37.895 -0.139  77.170  1.000 113.023 ? 336 ARG AAA NE  1 ? 
ATOM   2492 C  CZ  . ARG A 1 336 ? -39.181 0.103   76.922  1.000 113.185 ? 336 ARG AAA CZ  1 ? 
ATOM   2493 N  NH1 . ARG A 1 336 ? -40.124 -0.325  77.745  1.000 115.772 ? 336 ARG AAA NH1 1 ? 
ATOM   2494 N  NH2 . ARG A 1 336 ? -39.521 0.778   75.838  1.000 114.104 ? 336 ARG AAA NH2 1 ? 
ATOM   2495 N  N   . ARG A 1 337 ? -35.204 2.127   81.636  1.000 101.714 ? 337 ARG AAA N   1 ? 
ATOM   2496 C  CA  . ARG A 1 337 ? -35.675 3.210   82.506  1.000 100.257 ? 337 ARG AAA CA  1 ? 
ATOM   2497 C  C   . ARG A 1 337 ? -34.616 3.633   83.497  1.000 96.477  ? 337 ARG AAA C   1 ? 
ATOM   2498 O  O   . ARG A 1 337 ? -34.909 4.442   84.376  1.000 96.656  ? 337 ARG AAA O   1 ? 
ATOM   2499 C  CB  . ARG A 1 337 ? -37.014 2.855   83.164  1.000 104.822 ? 337 ARG AAA CB  1 ? 
ATOM   2500 C  CG  . ARG A 1 337 ? -37.041 1.566   83.972  1.000 113.059 ? 337 ARG AAA CG  1 ? 
ATOM   2501 C  CD  . ARG A 1 337 ? -38.461 1.035   84.085  1.000 115.592 ? 337 ARG AAA CD  1 ? 
ATOM   2502 N  NE  . ARG A 1 337 ? -38.875 0.258   82.920  1.000 117.560 ? 337 ARG AAA NE  1 ? 
ATOM   2503 C  CZ  . ARG A 1 337 ? -40.118 -0.152  82.674  1.000 116.558 ? 337 ARG AAA CZ  1 ? 
ATOM   2504 N  NH1 . ARG A 1 337 ? -41.103 0.149   83.503  1.000 117.372 ? 337 ARG AAA NH1 1 ? 
ATOM   2505 N  NH2 . ARG A 1 337 ? -40.374 -0.861  81.588  1.000 115.728 ? 337 ARG AAA NH2 1 ? 
ATOM   2506 N  N   . HIS A 1 338 ? -33.387 3.172   83.317  1.000 97.513  ? 338 HIS AAA N   1 ? 
ATOM   2507 C  CA  . HIS A 1 338 ? -32.274 3.640   84.159  1.000 100.932 ? 338 HIS AAA CA  1 ? 
ATOM   2508 C  C   . HIS A 1 338 ? -31.031 3.974   83.342  1.000 107.938 ? 338 HIS AAA C   1 ? 
ATOM   2509 O  O   . HIS A 1 338 ? -30.041 3.248   83.383  1.000 107.202 ? 338 HIS AAA O   1 ? 
ATOM   2510 C  CB  . HIS A 1 338 ? -31.996 2.626   85.282  1.000 98.802  ? 338 HIS AAA CB  1 ? 
ATOM   2511 C  CG  . HIS A 1 338 ? -32.990 2.685   86.396  1.000 97.859  ? 338 HIS AAA CG  1 ? 
ATOM   2512 N  ND1 . HIS A 1 338 ? -32.744 3.372   87.567  1.000 98.879  ? 338 HIS AAA ND1 1 ? 
ATOM   2513 C  CD2 . HIS A 1 338 ? -34.235 2.169   86.516  1.000 95.345  ? 338 HIS AAA CD2 1 ? 
ATOM   2514 C  CE1 . HIS A 1 338 ? -33.790 3.268   88.365  1.000 97.913  ? 338 HIS AAA CE1 1 ? 
ATOM   2515 N  NE2 . HIS A 1 338 ? -34.722 2.533   87.744  1.000 92.558  ? 338 HIS AAA NE2 1 ? 
ATOM   2516 N  N   . PRO A 1 339 ? -31.044 5.109   82.608  1.000 114.609 ? 339 PRO AAA N   1 ? 
ATOM   2517 C  CA  . PRO A 1 339 ? -29.838 5.656   81.989  1.000 120.430 ? 339 PRO AAA CA  1 ? 
ATOM   2518 C  C   . PRO A 1 339 ? -28.913 6.304   83.019  1.000 125.229 ? 339 PRO AAA C   1 ? 
ATOM   2519 O  O   . PRO A 1 339 ? -27.789 6.690   82.688  1.000 129.729 ? 339 PRO AAA O   1 ? 
ATOM   2520 C  CB  . PRO A 1 339 ? -30.338 6.715   80.988  1.000 117.142 ? 339 PRO AAA CB  1 ? 
ATOM   2521 C  CG  . PRO A 1 339 ? -31.858 6.736   81.118  1.000 114.992 ? 339 PRO AAA CG  1 ? 
ATOM   2522 C  CD  . PRO A 1 339 ? -32.223 5.948   82.358  1.000 110.946 ? 339 PRO AAA CD  1 ? 
ATOM   2523 N  N   . ASP A 1 340 ? -29.424 6.420   84.242  1.000 129.310 ? 340 ASP AAA N   1 ? 
ATOM   2524 C  CA  . ASP A 1 340 ? -28.682 6.999   85.378  1.000 129.834 ? 340 ASP AAA CA  1 ? 
ATOM   2525 C  C   . ASP A 1 340 ? -27.755 5.965   86.027  1.000 127.797 ? 340 ASP AAA C   1 ? 
ATOM   2526 O  O   . ASP A 1 340 ? -26.798 6.338   86.739  1.000 134.480 ? 340 ASP AAA O   1 ? 
ATOM   2527 C  CB  . ASP A 1 340 ? -29.645 7.625   86.397  1.000 132.572 ? 340 ASP AAA CB  1 ? 
ATOM   2528 C  CG  . ASP A 1 340 ? -30.791 6.730   86.850  1.000 135.595 ? 340 ASP AAA CG  1 ? 
ATOM   2529 O  OD1 . ASP A 1 340 ? -30.849 5.562   86.406  1.000 139.142 ? 340 ASP AAA OD1 1 ? 
ATOM   2530 O  OD2 . ASP A 1 340 ? -31.630 7.213   87.639  1.000 132.852 ? 340 ASP AAA OD2 1 ? 
ATOM   2531 N  N   . TYR A 1 341 ? -28.021 4.687   85.801  1.000 115.265 ? 341 TYR AAA N   1 ? 
ATOM   2532 C  CA  . TYR A 1 341 ? -27.243 3.587   86.408  1.000 104.335 ? 341 TYR AAA CA  1 ? 
ATOM   2533 C  C   . TYR A 1 341 ? -26.130 3.167   85.463  1.000 101.190 ? 341 TYR AAA C   1 ? 
ATOM   2534 O  O   . TYR A 1 341 ? -26.267 3.215   84.234  1.000 98.695  ? 341 TYR AAA O   1 ? 
ATOM   2535 C  CB  . TYR A 1 341 ? -28.183 2.409   86.685  1.000 97.458  ? 341 TYR AAA CB  1 ? 
ATOM   2536 C  CG  . TYR A 1 341 ? -29.100 2.556   87.874  1.000 88.026  ? 341 TYR AAA CG  1 ? 
ATOM   2537 C  CD1 . TYR A 1 341 ? -29.396 3.789   88.433  1.000 82.119  ? 341 TYR AAA CD1 1 ? 
ATOM   2538 C  CD2 . TYR A 1 341 ? -29.685 1.437   88.440  1.000 85.852  ? 341 TYR AAA CD2 1 ? 
ATOM   2539 C  CE1 . TYR A 1 341 ? -30.230 3.902   89.532  1.000 80.817  ? 341 TYR AAA CE1 1 ? 
ATOM   2540 C  CE2 . TYR A 1 341 ? -30.525 1.531   89.536  1.000 83.668  ? 341 TYR AAA CE2 1 ? 
ATOM   2541 C  CZ  . TYR A 1 341 ? -30.797 2.769   90.083  1.000 82.447  ? 341 TYR AAA CZ  1 ? 
ATOM   2542 O  OH  . TYR A 1 341 ? -31.628 2.855   91.159  1.000 88.491  ? 341 TYR AAA OH  1 ? 
ATOM   2543 N  N   . SER A 1 342 ? -25.038 2.724   86.051  1.000 99.551  ? 342 SER AAA N   1 ? 
ATOM   2544 C  CA  . SER A 1 342 ? -24.002 2.027   85.282  1.000 98.536  ? 342 SER AAA CA  1 ? 
ATOM   2545 C  C   . SER A 1 342 ? -24.585 0.743   84.684  1.000 92.128  ? 342 SER AAA C   1 ? 
ATOM   2546 O  O   . SER A 1 342 ? -25.579 0.188   85.196  1.000 92.240  ? 342 SER AAA O   1 ? 
ATOM   2547 C  CB  . SER A 1 342 ? -22.814 1.707   86.149  1.000 105.901 ? 342 SER AAA CB  1 ? 
ATOM   2548 O  OG  . SER A 1 342 ? -23.108 0.629   87.029  1.000 108.574 ? 342 SER AAA OG  1 ? 
ATOM   2549 N  N   . VAL A 1 343 ? -23.943 0.252   83.643  1.000 85.920  ? 343 VAL AAA N   1 ? 
ATOM   2550 C  CA  . VAL A 1 343 ? -24.206 -1.120  83.134  1.000 85.007  ? 343 VAL AAA CA  1 ? 
ATOM   2551 C  C   . VAL A 1 343 ? -23.864 -2.130  84.229  1.000 81.941  ? 343 VAL AAA C   1 ? 
ATOM   2552 O  O   . VAL A 1 343 ? -24.723 -2.958  84.604  1.000 80.551  ? 343 VAL AAA O   1 ? 
ATOM   2553 C  CB  . VAL A 1 343 ? -23.426 -1.373  81.830  1.000 88.055  ? 343 VAL AAA CB  1 ? 
ATOM   2554 C  CG1 . VAL A 1 343 ? -23.467 -2.835  81.408  1.000 90.228  ? 343 VAL AAA CG1 1 ? 
ATOM   2555 C  CG2 . VAL A 1 343 ? -23.921 -0.468  80.708  1.000 85.715  ? 343 VAL AAA CG2 1 ? 
ATOM   2556 N  N   . VAL A 1 344 ? -22.652 -2.061  84.761  1.000 80.132  ? 344 VAL AAA N   1 ? 
ATOM   2557 C  CA  . VAL A 1 344 ? -22.191 -3.057  85.764  1.000 82.650  ? 344 VAL AAA CA  1 ? 
ATOM   2558 C  C   . VAL A 1 344 ? -23.150 -3.133  86.951  1.000 80.657  ? 344 VAL AAA C   1 ? 
ATOM   2559 O  O   . VAL A 1 344 ? -23.434 -4.218  87.433  1.000 81.762  ? 344 VAL AAA O   1 ? 
ATOM   2560 C  CB  . VAL A 1 344 ? -20.741 -2.777  86.203  1.000 85.080  ? 344 VAL AAA CB  1 ? 
ATOM   2561 C  CG1 . VAL A 1 344 ? -19.785 -2.845  85.021  1.000 86.620  ? 344 VAL AAA CG1 1 ? 
ATOM   2562 C  CG2 . VAL A 1 344 ? -20.596 -1.453  86.934  1.000 84.262  ? 344 VAL AAA CG2 1 ? 
ATOM   2563 N  N   . LEU A 1 345 ? -23.659 -2.007  87.409  1.000 77.201  ? 345 LEU AAA N   1 ? 
ATOM   2564 C  CA  . LEU A 1 345 ? -24.725 -2.037  88.418  1.000 78.446  ? 345 LEU AAA CA  1 ? 
ATOM   2565 C  C   . LEU A 1 345 ? -25.898 -2.867  87.931  1.000 81.800  ? 345 LEU AAA C   1 ? 
ATOM   2566 O  O   . LEU A 1 345 ? -26.302 -3.818  88.612  1.000 84.978  ? 345 LEU AAA O   1 ? 
ATOM   2567 C  CB  . LEU A 1 345 ? -25.142 -0.593  88.724  1.000 73.188  ? 345 LEU AAA CB  1 ? 
ATOM   2568 C  CG  . LEU A 1 345 ? -26.345 -0.403  89.649  1.000 70.932  ? 345 LEU AAA CG  1 ? 
ATOM   2569 C  CD1 . LEU A 1 345 ? -26.318 -1.355  90.837  1.000 72.334  ? 345 LEU AAA CD1 1 ? 
ATOM   2570 C  CD2 . LEU A 1 345 ? -26.405 1.028   90.144  1.000 69.681  ? 345 LEU AAA CD2 1 ? 
ATOM   2571 N  N   . LEU A 1 346 ? -26.418 -2.494  86.775  1.000 81.206  ? 346 LEU AAA N   1 ? 
ATOM   2572 C  CA  . LEU A 1 346 ? -27.617 -3.142  86.201  1.000 81.500  ? 346 LEU AAA CA  1 ? 
ATOM   2573 C  C   . LEU A 1 346 ? -27.448 -4.651  86.085  1.000 80.946  ? 346 LEU AAA C   1 ? 
ATOM   2574 O  O   . LEU A 1 346 ? -28.353 -5.454  86.407  1.000 84.627  ? 346 LEU AAA O   1 ? 
ATOM   2575 C  CB  . LEU A 1 346 ? -27.886 -2.549  84.818  1.000 83.209  ? 346 LEU AAA CB  1 ? 
ATOM   2576 C  CG  . LEU A 1 346 ? -28.435 -1.129  84.825  1.000 86.073  ? 346 LEU AAA CG  1 ? 
ATOM   2577 C  CD1 . LEU A 1 346 ? -28.206 -0.454  83.481  1.000 88.141  ? 346 LEU AAA CD1 1 ? 
ATOM   2578 C  CD2 . LEU A 1 346 ? -29.909 -1.134  85.190  1.000 87.525  ? 346 LEU AAA CD2 1 ? 
ATOM   2579 N  N   . LEU A 1 347 ? -26.288 -5.035  85.610  1.000 76.165  ? 347 LEU AAA N   1 ? 
ATOM   2580 C  CA  . LEU A 1 347 ? -25.927 -6.442  85.626  1.000 75.676  ? 347 LEU AAA CA  1 ? 
ATOM   2581 C  C   . LEU A 1 347 ? -26.017 -6.992  87.056  1.000 78.762  ? 347 LEU AAA C   1 ? 
ATOM   2582 O  O   . LEU A 1 347 ? -26.758 -7.942  87.284  1.000 86.926  ? 347 LEU AAA O   1 ? 
ATOM   2583 C  CB  . LEU A 1 347 ? -24.559 -6.601  84.965  1.000 74.753  ? 347 LEU AAA CB  1 ? 
ATOM   2584 C  CG  . LEU A 1 347 ? -24.559 -6.266  83.472  1.000 76.137  ? 347 LEU AAA CG  1 ? 
ATOM   2585 C  CD1 . LEU A 1 347 ? -23.150 -6.255  82.905  1.000 79.439  ? 347 LEU AAA CD1 1 ? 
ATOM   2586 C  CD2 . LEU A 1 347 ? -25.432 -7.236  82.694  1.000 76.519  ? 347 LEU AAA CD2 1 ? 
ATOM   2587 N  N   . ARG A 1 348 ? -25.347 -6.382  88.026  1.000 78.469  ? 348 ARG AAA N   1 ? 
ATOM   2588 C  CA  . ARG A 1 348 ? -25.425 -6.880  89.423  1.000 82.935  ? 348 ARG AAA CA  1 ? 
ATOM   2589 C  C   . ARG A 1 348 ? -26.875 -7.058  89.833  1.000 83.980  ? 348 ARG AAA C   1 ? 
ATOM   2590 O  O   . ARG A 1 348 ? -27.226 -8.090  90.407  1.000 88.467  ? 348 ARG AAA O   1 ? 
ATOM   2591 C  CB  . ARG A 1 348 ? -24.829 -5.904  90.441  1.000 84.569  ? 348 ARG AAA CB  1 ? 
ATOM   2592 C  CG  . ARG A 1 348 ? -23.327 -5.709  90.325  1.000 89.433  ? 348 ARG AAA CG  1 ? 
ATOM   2593 C  CD  . ARG A 1 348 ? -22.865 -4.490  91.094  1.000 89.056  ? 348 ARG AAA CD  1 ? 
ATOM   2594 N  NE  . ARG A 1 348 ? -21.622 -3.952  90.559  1.000 86.502  ? 348 ARG AAA NE  1 ? 
ATOM   2595 C  CZ  . ARG A 1 348 ? -21.256 -2.676  90.622  1.000 83.719  ? 348 ARG AAA CZ  1 ? 
ATOM   2596 N  NH1 . ARG A 1 348 ? -22.040 -1.777  91.196  1.000 82.041  ? 348 ARG AAA NH1 1 ? 
ATOM   2597 N  NH2 . ARG A 1 348 ? -20.101 -2.299  90.103  1.000 85.174  ? 348 ARG AAA NH2 1 ? 
ATOM   2598 N  N   . LEU A 1 349 ? -27.685 -6.044  89.598  1.000 83.333  ? 349 LEU AAA N   1 ? 
ATOM   2599 C  CA  . LEU A 1 349 ? -29.088 -6.123  90.015  1.000 83.313  ? 349 LEU AAA CA  1 ? 
ATOM   2600 C  C   . LEU A 1 349 ? -29.685 -7.332  89.327  1.000 80.661  ? 349 LEU AAA C   1 ? 
ATOM   2601 O  O   . LEU A 1 349 ? -30.387 -8.108  89.952  1.000 77.468  ? 349 LEU AAA O   1 ? 
ATOM   2602 C  CB  . LEU A 1 349 ? -29.856 -4.860  89.607  1.000 82.707  ? 349 LEU AAA CB  1 ? 
ATOM   2603 C  CG  . LEU A 1 349 ? -29.346 -3.524  90.145  1.000 81.604  ? 349 LEU AAA CG  1 ? 
ATOM   2604 C  CD1 . LEU A 1 349 ? -30.284 -2.405  89.720  1.000 82.344  ? 349 LEU AAA CD1 1 ? 
ATOM   2605 C  CD2 . LEU A 1 349 ? -29.192 -3.545  91.657  1.000 80.008  ? 349 LEU AAA CD2 1 ? 
ATOM   2606 N  N   . ALA A 1 350 ? -29.393 -7.477  88.049  1.000 77.748  ? 350 ALA AAA N   1 ? 
ATOM   2607 C  CA  . ALA A 1 350 ? -29.927 -8.605  87.285  1.000 79.078  ? 350 ALA AAA CA  1 ? 
ATOM   2608 C  C   . ALA A 1 350 ? -29.551 -9.936  87.932  1.000 83.859  ? 350 ALA AAA C   1 ? 
ATOM   2609 O  O   . ALA A 1 350 ? -30.391 -10.866 88.029  1.000 91.244  ? 350 ALA AAA O   1 ? 
ATOM   2610 C  CB  . ALA A 1 350 ? -29.434 -8.539  85.861  1.000 78.305  ? 350 ALA AAA CB  1 ? 
ATOM   2611 N  N   . LYS A 1 351 ? -28.302 -10.007 88.372  1.000 89.879  ? 351 LYS AAA N   1 ? 
ATOM   2612 C  CA  . LYS A 1 351 ? -27.741 -11.201 89.025  1.000 98.518  ? 351 LYS AAA CA  1 ? 
ATOM   2613 C  C   . LYS A 1 351 ? -28.434 -11.475 90.356  1.000 97.518  ? 351 LYS AAA C   1 ? 
ATOM   2614 O  O   . LYS A 1 351 ? -28.827 -12.621 90.636  1.000 100.484 ? 351 LYS AAA O   1 ? 
ATOM   2615 C  CB  . LYS A 1 351 ? -26.231 -11.015 89.221  1.000 104.707 ? 351 LYS AAA CB  1 ? 
ATOM   2616 C  CG  . LYS A 1 351 ? -25.476 -12.225 89.757  1.000 112.191 ? 351 LYS AAA CG  1 ? 
ATOM   2617 C  CD  . LYS A 1 351 ? -25.544 -13.445 88.859  1.000 118.126 ? 351 LYS AAA CD  1 ? 
ATOM   2618 C  CE  . LYS A 1 351 ? -24.729 -14.610 89.382  1.000 121.400 ? 351 LYS AAA CE  1 ? 
ATOM   2619 N  NZ  . LYS A 1 351 ? -25.093 -15.877 88.706  1.000 125.493 ? 351 LYS AAA NZ  1 ? 
ATOM   2620 N  N   . THR A 1 352 ? -28.563 -10.431 91.161  1.000 91.166  ? 352 THR AAA N   1 ? 
ATOM   2621 C  CA  . THR A 1 352 ? -29.301 -10.480 92.428  1.000 90.075  ? 352 THR AAA CA  1 ? 
ATOM   2622 C  C   . THR A 1 352 ? -30.700 -11.009 92.161  1.000 93.531  ? 352 THR AAA C   1 ? 
ATOM   2623 O  O   . THR A 1 352 ? -31.142 -11.953 92.820  1.000 105.162 ? 352 THR AAA O   1 ? 
ATOM   2624 C  CB  . THR A 1 352 ? -29.426 -9.083  93.048  1.000 86.192  ? 352 THR AAA CB  1 ? 
ATOM   2625 O  OG1 . THR A 1 352 ? -28.109 -8.609  93.320  1.000 88.925  ? 352 THR AAA OG1 1 ? 
ATOM   2626 C  CG2 . THR A 1 352 ? -30.260 -9.059  94.310  1.000 85.083  ? 352 THR AAA CG2 1 ? 
ATOM   2627 N  N   . TYR A 1 353 ? -31.382 -10.405 91.202  1.000 88.773  ? 353 TYR AAA N   1 ? 
ATOM   2628 C  CA  . TYR A 1 353 ? -32.732 -10.850 90.794  1.000 83.995  ? 353 TYR AAA CA  1 ? 
ATOM   2629 C  C   . TYR A 1 353 ? -32.739 -12.344 90.429  1.000 81.877  ? 353 TYR AAA C   1 ? 
ATOM   2630 O  O   . TYR A 1 353 ? -33.544 -13.129 91.004  1.000 80.613  ? 353 TYR AAA O   1 ? 
ATOM   2631 C  CB  . TYR A 1 353 ? -33.251 -9.992  89.634  1.000 81.785  ? 353 TYR AAA CB  1 ? 
ATOM   2632 C  CG  . TYR A 1 353 ? -34.669 -10.287 89.216  1.000 78.388  ? 353 TYR AAA CG  1 ? 
ATOM   2633 C  CD1 . TYR A 1 353 ? -35.742 -9.850  89.974  1.000 78.194  ? 353 TYR AAA CD1 1 ? 
ATOM   2634 C  CD2 . TYR A 1 353 ? -34.938 -11.002 88.061  1.000 78.007  ? 353 TYR AAA CD2 1 ? 
ATOM   2635 C  CE1 . TYR A 1 353 ? -37.048 -10.126 89.603  1.000 80.311  ? 353 TYR AAA CE1 1 ? 
ATOM   2636 C  CE2 . TYR A 1 353 ? -36.238 -11.287 87.675  1.000 80.688  ? 353 TYR AAA CE2 1 ? 
ATOM   2637 C  CZ  . TYR A 1 353 ? -37.298 -10.849 88.450  1.000 81.564  ? 353 TYR AAA CZ  1 ? 
ATOM   2638 O  OH  . TYR A 1 353 ? -38.581 -11.132 88.073  1.000 82.199  ? 353 TYR AAA OH  1 ? 
ATOM   2639 N  N   . GLU A 1 354 ? -31.870 -12.751 89.502  1.000 80.722  ? 354 GLU AAA N   1 ? 
ATOM   2640 C  CA  . GLU A 1 354 ? -31.804 -14.183 89.101  1.000 82.703  ? 354 GLU AAA CA  1 ? 
ATOM   2641 C  C   . GLU A 1 354 ? -31.669 -15.030 90.366  1.000 86.813  ? 354 GLU AAA C   1 ? 
ATOM   2642 O  O   . GLU A 1 354 ? -32.539 -15.885 90.684  1.000 89.404  ? 354 GLU AAA O   1 ? 
ATOM   2643 C  CB  . GLU A 1 354 ? -30.631 -14.369 88.135  1.000 80.478  ? 354 GLU AAA CB  1 ? 
ATOM   2644 C  CG  . GLU A 1 354 ? -30.519 -15.757 87.535  1.000 81.397  ? 354 GLU AAA CG  1 ? 
ATOM   2645 C  CD  . GLU A 1 354 ? -29.419 -15.881 86.492  1.000 82.724  ? 354 GLU AAA CD  1 ? 
ATOM   2646 O  OE1 . GLU A 1 354 ? -28.669 -14.895 86.299  1.000 80.758  ? 354 GLU AAA OE1 1 ? 
ATOM   2647 O  OE2 . GLU A 1 354 ? -29.312 -16.959 85.869  1.000 84.496  ? 354 GLU AAA OE2 1 ? 
ATOM   2648 N  N   . THR A 1 355 ? -30.592 -14.747 91.084  1.000 90.169  ? 355 THR AAA N   1 ? 
ATOM   2649 C  CA  . THR A 1 355 ? -30.248 -15.391 92.364  1.000 96.936  ? 355 THR AAA CA  1 ? 
ATOM   2650 C  C   . THR A 1 355 ? -31.503 -15.570 93.210  1.000 102.164 ? 355 THR AAA C   1 ? 
ATOM   2651 O  O   . THR A 1 355 ? -31.887 -16.695 93.548  1.000 110.363 ? 355 THR AAA O   1 ? 
ATOM   2652 C  CB  . THR A 1 355 ? -29.180 -14.555 93.082  1.000 99.215  ? 355 THR AAA CB  1 ? 
ATOM   2653 O  OG1 . THR A 1 355 ? -27.967 -14.722 92.348  1.000 94.738  ? 355 THR AAA OG1 1 ? 
ATOM   2654 C  CG2 . THR A 1 355 ? -28.982 -14.932 94.535  1.000 103.825 ? 355 THR AAA CG2 1 ? 
ATOM   2655 N  N   . THR A 1 356 ? -32.136 -14.465 93.550  1.000 100.292 ? 356 THR AAA N   1 ? 
ATOM   2656 C  CA  . THR A 1 356 ? -33.319 -14.496 94.420  1.000 99.507  ? 356 THR AAA CA  1 ? 
ATOM   2657 C  C   . THR A 1 356 ? -34.457 -15.313 93.829  1.000 104.725 ? 356 THR AAA C   1 ? 
ATOM   2658 O  O   . THR A 1 356 ? -35.099 -16.095 94.554  1.000 111.231 ? 356 THR AAA O   1 ? 
ATOM   2659 C  CB  . THR A 1 356 ? -33.758 -13.072 94.777  1.000 96.917  ? 356 THR AAA CB  1 ? 
ATOM   2660 O  OG1 . THR A 1 356 ? -32.624 -12.430 95.363  1.000 89.409  ? 356 THR AAA OG1 1 ? 
ATOM   2661 C  CG2 . THR A 1 356 ? -34.934 -13.037 95.730  1.000 99.313  ? 356 THR AAA CG2 1 ? 
ATOM   2662 N  N   . LEU A 1 357 ? -34.718 -15.159 92.543  1.000 105.865 ? 357 LEU AAA N   1 ? 
ATOM   2663 C  CA  . LEU A 1 357 ? -35.744 -16.034 91.947  1.000 106.878 ? 357 LEU AAA CA  1 ? 
ATOM   2664 C  C   . LEU A 1 357 ? -35.372 -17.495 92.190  1.000 112.033 ? 357 LEU AAA C   1 ? 
ATOM   2665 O  O   . LEU A 1 357 ? -36.240 -18.318 92.590  1.000 118.633 ? 357 LEU AAA O   1 ? 
ATOM   2666 C  CB  . LEU A 1 357 ? -35.928 -15.756 90.449  1.000 102.437 ? 357 LEU AAA CB  1 ? 
ATOM   2667 C  CG  . LEU A 1 357 ? -36.852 -14.591 90.078  1.000 100.034 ? 357 LEU AAA CG  1 ? 
ATOM   2668 C  CD1 . LEU A 1 357 ? -37.453 -14.803 88.696  1.000 97.236  ? 357 LEU AAA CD1 1 ? 
ATOM   2669 C  CD2 . LEU A 1 357 ? -37.962 -14.380 91.102  1.000 97.626  ? 357 LEU AAA CD2 1 ? 
ATOM   2670 N  N   . GLU A 1 358 ? -34.108 -17.817 91.964  1.000 112.269 ? 358 GLU AAA N   1 ? 
ATOM   2671 C  CA  . GLU A 1 358 ? -33.648 -19.198 92.173  1.000 113.757 ? 358 GLU AAA CA  1 ? 
ATOM   2672 C  C   . GLU A 1 358 ? -34.096 -19.743 93.535  1.000 114.413 ? 358 GLU AAA C   1 ? 
ATOM   2673 O  O   . GLU A 1 358 ? -34.776 -20.795 93.597  1.000 116.682 ? 358 GLU AAA O   1 ? 
ATOM   2674 C  CB  . GLU A 1 358 ? -32.128 -19.297 92.036  1.000 116.926 ? 358 GLU AAA CB  1 ? 
ATOM   2675 C  CG  . GLU A 1 358 ? -31.615 -20.725 91.985  1.000 123.252 ? 358 GLU AAA CG  1 ? 
ATOM   2676 C  CD  . GLU A 1 358 ? -31.881 -21.469 90.686  1.000 127.489 ? 358 GLU AAA CD  1 ? 
ATOM   2677 O  OE1 . GLU A 1 358 ? -33.063 -21.719 90.370  1.000 122.694 ? 358 GLU AAA OE1 1 ? 
ATOM   2678 O  OE2 . GLU A 1 358 ? -30.900 -21.804 89.992  1.000 140.391 ? 358 GLU AAA OE2 1 ? 
ATOM   2679 N  N   . LYS A 1 359 ? -33.728 -19.033 94.596  1.000 115.722 ? 359 LYS AAA N   1 ? 
ATOM   2680 C  CA  . LYS A 1 359 ? -33.984 -19.446 95.995  1.000 118.748 ? 359 LYS AAA CA  1 ? 
ATOM   2681 C  C   . LYS A 1 359 ? -35.473 -19.427 96.279  1.000 125.678 ? 359 LYS AAA C   1 ? 
ATOM   2682 O  O   . LYS A 1 359 ? -35.995 -20.378 96.861  1.000 134.119 ? 359 LYS AAA O   1 ? 
ATOM   2683 C  CB  . LYS A 1 359 ? -33.261 -18.510 96.968  1.000 116.575 ? 359 LYS AAA CB  1 ? 
ATOM   2684 N  N   . CYS A 1 360 ? -36.131 -18.355 95.874  1.000 129.630 ? 360 CYS AAA N   1 ? 
ATOM   2685 C  CA  . CYS A 1 360 ? -37.564 -18.195 96.172  1.000 133.058 ? 360 CYS AAA CA  1 ? 
ATOM   2686 C  C   . CYS A 1 360 ? -38.462 -19.210 95.486  1.000 134.697 ? 360 CYS AAA C   1 ? 
ATOM   2687 O  O   . CYS A 1 360 ? -39.325 -19.781 96.163  1.000 140.110 ? 360 CYS AAA O   1 ? 
ATOM   2688 C  CB  . CYS A 1 360 ? -37.967 -16.757 95.888  1.000 137.483 ? 360 CYS AAA CB  1 ? 
ATOM   2689 S  SG  . CYS A 1 360 ? -37.190 -15.649 97.091  1.000 147.868 ? 360 CYS AAA SG  1 ? 
ATOM   2690 N  N   . CYS A 1 361 ? -38.262 -19.432 94.195  1.000 131.338 ? 361 CYS AAA N   1 ? 
ATOM   2691 C  CA  . CYS A 1 361 ? -39.126 -20.380 93.462  1.000 127.769 ? 361 CYS AAA CA  1 ? 
ATOM   2692 C  C   . CYS A 1 361 ? -38.873 -21.829 93.881  1.000 127.382 ? 361 CYS AAA C   1 ? 
ATOM   2693 O  O   . CYS A 1 361 ? -39.490 -22.742 93.295  1.000 119.564 ? 361 CYS AAA O   1 ? 
ATOM   2694 C  CB  . CYS A 1 361 ? -38.937 -20.261 91.954  1.000 123.656 ? 361 CYS AAA CB  1 ? 
ATOM   2695 S  SG  . CYS A 1 361 ? -39.516 -18.682 91.287  1.000 129.164 ? 361 CYS AAA SG  1 ? 
ATOM   2696 N  N   . ALA A 1 362 ? -38.008 -22.031 94.868  1.000 134.527 ? 362 ALA AAA N   1 ? 
ATOM   2697 C  CA  . ALA A 1 362 ? -37.824 -23.332 95.530  1.000 138.015 ? 362 ALA AAA CA  1 ? 
ATOM   2698 C  C   . ALA A 1 362 ? -38.391 -23.309 96.947  1.000 145.430 ? 362 ALA AAA C   1 ? 
ATOM   2699 O  O   . ALA A 1 362 ? -38.011 -24.173 97.761  1.000 155.397 ? 362 ALA AAA O   1 ? 
ATOM   2700 C  CB  . ALA A 1 362 ? -36.356 -23.687 95.534  1.000 135.384 ? 362 ALA AAA CB  1 ? 
ATOM   2701 N  N   . ALA A 1 363 ? -39.297 -22.373 97.241  1.000 148.451 ? 363 ALA AAA N   1 ? 
ATOM   2702 C  CA  . ALA A 1 363 ? -39.862 -22.229 98.601  1.000 146.965 ? 363 ALA AAA CA  1 ? 
ATOM   2703 C  C   . ALA A 1 363 ? -41.327 -22.679 98.695  1.000 149.453 ? 363 ALA AAA C   1 ? 
ATOM   2704 O  O   . ALA A 1 363 ? -41.944 -23.122 97.687  1.000 144.218 ? 363 ALA AAA O   1 ? 
ATOM   2705 C  CB  . ALA A 1 363 ? -39.705 -20.795 99.050  1.000 145.713 ? 363 ALA AAA CB  1 ? 
ATOM   2706 N  N   . ALA A 1 364 ? -41.881 -22.553 99.903  1.000 155.871 ? 364 ALA AAA N   1 ? 
ATOM   2707 C  CA  . ALA A 1 364 ? -43.279 -22.901 100.228 1.000 160.774 ? 364 ALA AAA CA  1 ? 
ATOM   2708 C  C   . ALA A 1 364 ? -44.245 -21.959 99.509  1.000 168.849 ? 364 ALA AAA C   1 ? 
ATOM   2709 O  O   . ALA A 1 364 ? -45.076 -22.459 98.721  1.000 178.039 ? 364 ALA AAA O   1 ? 
ATOM   2710 C  CB  . ALA A 1 364 ? -43.488 -22.870 101.724 1.000 157.532 ? 364 ALA AAA CB  1 ? 
ATOM   2711 N  N   . ASP A 1 365 ? -44.135 -20.652 99.772  1.000 168.614 ? 365 ASP AAA N   1 ? 
ATOM   2712 C  CA  . ASP A 1 365 ? -44.850 -19.598 99.006  1.000 164.687 ? 365 ASP AAA CA  1 ? 
ATOM   2713 C  C   . ASP A 1 365 ? -43.833 -18.646 98.386  1.000 153.909 ? 365 ASP AAA C   1 ? 
ATOM   2714 O  O   . ASP A 1 365 ? -43.335 -17.736 99.058  1.000 148.408 ? 365 ASP AAA O   1 ? 
ATOM   2715 C  CB  . ASP A 1 365 ? -45.879 -18.867 99.877  1.000 170.477 ? 365 ASP AAA CB  1 ? 
ATOM   2716 C  CG  . ASP A 1 365 ? -46.999 -18.194 99.092  1.000 171.700 ? 365 ASP AAA CG  1 ? 
ATOM   2717 O  OD1 . ASP A 1 365 ? -47.119 -18.466 97.878  1.000 169.925 ? 365 ASP AAA OD1 1 ? 
ATOM   2718 O  OD2 . ASP A 1 365 ? -47.749 -17.404 99.705  1.000 167.637 ? 365 ASP AAA OD2 1 ? 
ATOM   2719 N  N   . PRO A 1 366 ? -43.500 -18.846 97.090  1.000 145.410 ? 366 PRO AAA N   1 ? 
ATOM   2720 C  CA  . PRO A 1 366 ? -42.493 -18.030 96.424  1.000 143.136 ? 366 PRO AAA CA  1 ? 
ATOM   2721 C  C   . PRO A 1 366 ? -42.868 -16.560 96.315  1.000 147.083 ? 366 PRO AAA C   1 ? 
ATOM   2722 O  O   . PRO A 1 366 ? -42.030 -15.691 96.576  1.000 153.307 ? 366 PRO AAA O   1 ? 
ATOM   2723 C  CB  . PRO A 1 366 ? -42.385 -18.629 95.013  1.000 140.071 ? 366 PRO AAA CB  1 ? 
ATOM   2724 C  CG  . PRO A 1 366 ? -42.978 -20.014 95.136  1.000 141.709 ? 366 PRO AAA CG  1 ? 
ATOM   2725 C  CD  . PRO A 1 366 ? -44.047 -19.882 96.199  1.000 145.856 ? 366 PRO AAA CD  1 ? 
ATOM   2726 N  N   . HIS A 1 367 ? -44.112 -16.302 95.940  1.000 150.241 ? 367 HIS AAA N   1 ? 
ATOM   2727 C  CA  . HIS A 1 367 ? -44.644 -14.926 95.917  1.000 154.214 ? 367 HIS AAA CA  1 ? 
ATOM   2728 C  C   . HIS A 1 367 ? -44.117 -14.158 97.127  1.000 147.794 ? 367 HIS AAA C   1 ? 
ATOM   2729 O  O   . HIS A 1 367 ? -43.661 -13.013 96.966  1.000 149.002 ? 367 HIS AAA O   1 ? 
ATOM   2730 C  CB  . HIS A 1 367 ? -46.180 -14.911 95.857  1.000 165.302 ? 367 HIS AAA CB  1 ? 
ATOM   2731 C  CG  . HIS A 1 367 ? -46.780 -13.546 95.984  1.000 173.539 ? 367 HIS AAA CG  1 ? 
ATOM   2732 N  ND1 . HIS A 1 367 ? -46.242 -12.440 95.352  1.000 178.282 ? 367 HIS AAA ND1 1 ? 
ATOM   2733 C  CD2 . HIS A 1 367 ? -47.868 -13.103 96.654  1.000 174.238 ? 367 HIS AAA CD2 1 ? 
ATOM   2734 C  CE1 . HIS A 1 367 ? -46.967 -11.375 95.634  1.000 174.387 ? 367 HIS AAA CE1 1 ? 
ATOM   2735 N  NE2 . HIS A 1 367 ? -47.972 -11.756 96.431  1.000 172.153 ? 367 HIS AAA NE2 1 ? 
ATOM   2736 N  N   . GLU A 1 368 ? -44.144 -14.789 98.295  1.000 141.964 ? 368 GLU AAA N   1 ? 
ATOM   2737 C  CA  . GLU A 1 368 ? -43.700 -14.153 99.551  1.000 141.230 ? 368 GLU AAA CA  1 ? 
ATOM   2738 C  C   . GLU A 1 368 ? -42.196 -13.994 99.542  1.000 137.040 ? 368 GLU AAA C   1 ? 
ATOM   2739 O  O   . GLU A 1 368 ? -41.673 -12.894 99.784  1.000 136.644 ? 368 GLU AAA O   1 ? 
ATOM   2740 C  CB  . GLU A 1 368 ? -44.105 -14.983 100.774 1.000 144.967 ? 368 GLU AAA CB  1 ? 
ATOM   2741 C  CG  . GLU A 1 368 ? -45.590 -15.296 100.862 1.000 144.789 ? 368 GLU AAA CG  1 ? 
ATOM   2742 C  CD  . GLU A 1 368 ? -46.494 -14.113 101.165 1.000 142.999 ? 368 GLU AAA CD  1 ? 
ATOM   2743 O  OE1 . GLU A 1 368 ? -46.090 -13.247 101.969 1.000 141.985 ? 368 GLU AAA OE1 1 ? 
ATOM   2744 O  OE2 . GLU A 1 368 ? -47.604 -14.067 100.600 1.000 142.064 ? 368 GLU AAA OE2 1 ? 
ATOM   2745 N  N   . CYS A 1 369 ? -41.520 -15.091 99.255  1.000 134.429 ? 369 CYS AAA N   1 ? 
ATOM   2746 C  CA  . CYS A 1 369 ? -40.052 -15.139 99.296  1.000 134.727 ? 369 CYS AAA CA  1 ? 
ATOM   2747 C  C   . CYS A 1 369 ? -39.423 -14.021 98.467  1.000 129.313 ? 369 CYS AAA C   1 ? 
ATOM   2748 O  O   . CYS A 1 369 ? -38.543 -13.292 98.980  1.000 134.872 ? 369 CYS AAA O   1 ? 
ATOM   2749 C  CB  . CYS A 1 369 ? -39.494 -16.490 98.860  1.000 140.780 ? 369 CYS AAA CB  1 ? 
ATOM   2750 S  SG  . CYS A 1 369 ? -37.680 -16.533 98.863  1.000 146.575 ? 369 CYS AAA SG  1 ? 
ATOM   2751 N  N   . TYR A 1 370 ? -39.839 -13.872 97.216  1.000 116.766 ? 370 TYR AAA N   1 ? 
ATOM   2752 C  CA  . TYR A 1 370 ? -39.188 -12.887 96.320  1.000 108.405 ? 370 TYR AAA CA  1 ? 
ATOM   2753 C  C   . TYR A 1 370 ? -39.808 -11.496 96.402  1.000 109.653 ? 370 TYR AAA C   1 ? 
ATOM   2754 O  O   . TYR A 1 370 ? -39.208 -10.543 95.864  1.000 118.775 ? 370 TYR AAA O   1 ? 
ATOM   2755 C  CB  . TYR A 1 370 ? -39.147 -13.384 94.872  1.000 101.565 ? 370 TYR AAA CB  1 ? 
ATOM   2756 C  CG  . TYR A 1 370 ? -40.480 -13.625 94.214  1.000 98.184  ? 370 TYR AAA CG  1 ? 
ATOM   2757 C  CD1 . TYR A 1 370 ? -41.239 -12.575 93.725  1.000 97.698  ? 370 TYR AAA CD1 1 ? 
ATOM   2758 C  CD2 . TYR A 1 370 ? -40.965 -14.912 94.037  1.000 95.222  ? 370 TYR AAA CD2 1 ? 
ATOM   2759 C  CE1 . TYR A 1 370 ? -42.458 -12.794 93.104  1.000 95.595  ? 370 TYR AAA CE1 1 ? 
ATOM   2760 C  CE2 . TYR A 1 370 ? -42.182 -15.149 93.420  1.000 92.944  ? 370 TYR AAA CE2 1 ? 
ATOM   2761 C  CZ  . TYR A 1 370 ? -42.931 -14.086 92.948  1.000 92.776  ? 370 TYR AAA CZ  1 ? 
ATOM   2762 O  OH  . TYR A 1 370 ? -44.130 -14.323 92.341  1.000 88.484  ? 370 TYR AAA OH  1 ? 
ATOM   2763 N  N   . ALA A 1 371 ? -40.956 -11.360 97.060  1.000 110.231 ? 371 ALA AAA N   1 ? 
ATOM   2764 C  CA  . ALA A 1 371 ? -41.744 -10.113 97.059  1.000 116.611 ? 371 ALA AAA CA  1 ? 
ATOM   2765 C  C   . ALA A 1 371 ? -40.928 -8.866  97.391  1.000 118.156 ? 371 ALA AAA C   1 ? 
ATOM   2766 O  O   . ALA A 1 371 ? -41.285 -7.772  96.901  1.000 114.310 ? 371 ALA AAA O   1 ? 
ATOM   2767 C  CB  . ALA A 1 371 ? -42.883 -10.254 98.038  1.000 121.059 ? 371 ALA AAA CB  1 ? 
ATOM   2768 N  N   . LYS A 1 372 ? -39.875 -9.015  98.190  1.000 121.528 ? 372 LYS AAA N   1 ? 
ATOM   2769 C  CA  . LYS A 1 372 ? -39.056 -7.880  98.652  1.000 124.430 ? 372 LYS AAA CA  1 ? 
ATOM   2770 C  C   . LYS A 1 372 ? -37.751 -7.726  97.878  1.000 119.711 ? 372 LYS AAA C   1 ? 
ATOM   2771 O  O   . LYS A 1 372 ? -36.848 -6.975  98.322  1.000 118.494 ? 372 LYS AAA O   1 ? 
ATOM   2772 C  CB  . LYS A 1 372 ? -38.749 -8.069  100.142 1.000 127.293 ? 372 LYS AAA CB  1 ? 
ATOM   2773 C  CG  . LYS A 1 372 ? -39.939 -8.477  101.003 1.000 127.663 ? 372 LYS AAA CG  1 ? 
ATOM   2774 N  N   . VAL A 1 373 ? -37.634 -8.392  96.739  1.000 114.738 ? 373 VAL AAA N   1 ? 
ATOM   2775 C  CA  . VAL A 1 373 ? -36.354 -8.450  95.990  1.000 112.176 ? 373 VAL AAA CA  1 ? 
ATOM   2776 C  C   . VAL A 1 373 ? -35.794 -7.060  95.648  1.000 113.773 ? 373 VAL AAA C   1 ? 
ATOM   2777 O  O   . VAL A 1 373 ? -34.562 -6.932  95.459  1.000 118.616 ? 373 VAL AAA O   1 ? 
ATOM   2778 C  CB  . VAL A 1 373 ? -36.524 -9.302  94.717  1.000 111.094 ? 373 VAL AAA CB  1 ? 
ATOM   2779 C  CG1 . VAL A 1 373 ? -37.399 -8.619  93.674  1.000 106.765 ? 373 VAL AAA CG1 1 ? 
ATOM   2780 C  CG2 . VAL A 1 373 ? -35.183 -9.699  94.121  1.000 114.942 ? 373 VAL AAA CG2 1 ? 
ATOM   2781 N  N   . PHE A 1 374 ? -36.642 -6.043  95.535  1.000 116.873 ? 374 PHE AAA N   1 ? 
ATOM   2782 C  CA  . PHE A 1 374 ? -36.187 -4.659  95.267  1.000 127.352 ? 374 PHE AAA CA  1 ? 
ATOM   2783 C  C   . PHE A 1 374 ? -35.454 -4.049  96.457  1.000 134.570 ? 374 PHE AAA C   1 ? 
ATOM   2784 O  O   . PHE A 1 374 ? -34.560 -3.212  96.262  1.000 145.555 ? 374 PHE AAA O   1 ? 
ATOM   2785 C  CB  . PHE A 1 374 ? -37.369 -3.795  94.813  1.000 128.389 ? 374 PHE AAA CB  1 ? 
ATOM   2786 C  CG  . PHE A 1 374 ? -37.694 -3.918  93.344  1.000 130.998 ? 374 PHE AAA CG  1 ? 
ATOM   2787 C  CD1 . PHE A 1 374 ? -38.098 -5.129  92.800  1.000 132.333 ? 374 PHE AAA CD1 1 ? 
ATOM   2788 C  CD2 . PHE A 1 374 ? -37.584 -2.824  92.497  1.000 132.244 ? 374 PHE AAA CD2 1 ? 
ATOM   2789 C  CE1 . PHE A 1 374 ? -38.385 -5.242  91.447  1.000 131.768 ? 374 PHE AAA CE1 1 ? 
ATOM   2790 C  CE2 . PHE A 1 374 ? -37.874 -2.939  91.145  1.000 134.110 ? 374 PHE AAA CE2 1 ? 
ATOM   2791 C  CZ  . PHE A 1 374 ? -38.275 -4.147  90.622  1.000 132.057 ? 374 PHE AAA CZ  1 ? 
ATOM   2792 N  N   . ASP A 1 375 ? -35.818 -4.447  97.668  1.000 135.062 ? 375 ASP AAA N   1 ? 
ATOM   2793 C  CA  . ASP A 1 375 ? -35.128 -3.933  98.867  1.000 134.457 ? 375 ASP AAA CA  1 ? 
ATOM   2794 C  C   . ASP A 1 375 ? -33.648 -4.272  98.731  1.000 129.711 ? 375 ASP AAA C   1 ? 
ATOM   2795 O  O   . ASP A 1 375 ? -32.774 -3.452  99.075  1.000 132.581 ? 375 ASP AAA O   1 ? 
ATOM   2796 C  CB  . ASP A 1 375 ? -35.718 -4.528  100.147 1.000 138.923 ? 375 ASP AAA CB  1 ? 
ATOM   2797 C  CG  . ASP A 1 375 ? -37.216 -4.312  100.278 1.000 143.710 ? 375 ASP AAA CG  1 ? 
ATOM   2798 O  OD1 . ASP A 1 375 ? -37.788 -3.626  99.402  1.000 146.196 ? 375 ASP AAA OD1 1 ? 
ATOM   2799 O  OD2 . ASP A 1 375 ? -37.799 -4.842  101.245 1.000 143.604 ? 375 ASP AAA OD2 1 ? 
ATOM   2800 N  N   . GLU A 1 376 ? -33.379 -5.454  98.194  1.000 119.188 ? 376 GLU AAA N   1 ? 
ATOM   2801 C  CA  . GLU A 1 376 ? -31.994 -5.893  97.989  1.000 109.086 ? 376 GLU AAA CA  1 ? 
ATOM   2802 C  C   . GLU A 1 376 ? -31.240 -4.887  97.143  1.000 101.411 ? 376 GLU AAA C   1 ? 
ATOM   2803 O  O   . GLU A 1 376 ? -30.025 -4.748  97.314  1.000 96.960  ? 376 GLU AAA O   1 ? 
ATOM   2804 C  CB  . GLU A 1 376 ? -31.923 -7.278  97.347  1.000 110.357 ? 376 GLU AAA CB  1 ? 
ATOM   2805 C  CG  . GLU A 1 376 ? -32.432 -8.389  98.246  1.000 113.302 ? 376 GLU AAA CG  1 ? 
ATOM   2806 C  CD  . GLU A 1 376 ? -31.959 -9.781  97.857  1.000 116.514 ? 376 GLU AAA CD  1 ? 
ATOM   2807 O  OE1 . GLU A 1 376 ? -30.736 -9.967  97.686  1.000 117.562 ? 376 GLU AAA OE1 1 ? 
ATOM   2808 O  OE2 . GLU A 1 376 ? -32.817 -10.676 97.716  1.000 118.019 ? 376 GLU AAA OE2 1 ? 
ATOM   2809 N  N   . PHE A 1 377 ? -31.935 -4.183  96.271  1.000 97.232  ? 377 PHE AAA N   1 ? 
ATOM   2810 C  CA  . PHE A 1 377 ? -31.259 -3.273  95.330  1.000 98.083  ? 377 PHE AAA CA  1 ? 
ATOM   2811 C  C   . PHE A 1 377 ? -30.707 -2.006  95.987  1.000 99.068  ? 377 PHE AAA C   1 ? 
ATOM   2812 O  O   . PHE A 1 377 ? -29.580 -1.584  95.659  1.000 103.545 ? 377 PHE AAA O   1 ? 
ATOM   2813 C  CB  . PHE A 1 377 ? -32.197 -2.965  94.156  1.000 97.730  ? 377 PHE AAA CB  1 ? 
ATOM   2814 C  CG  . PHE A 1 377 ? -32.652 -4.175  93.373  1.000 95.738  ? 377 PHE AAA CG  1 ? 
ATOM   2815 C  CD1 . PHE A 1 377 ? -31.995 -5.395  93.481  1.000 96.372  ? 377 PHE AAA CD1 1 ? 
ATOM   2816 C  CD2 . PHE A 1 377 ? -33.721 -4.088  92.493  1.000 93.704  ? 377 PHE AAA CD2 1 ? 
ATOM   2817 C  CE1 . PHE A 1 377 ? -32.409 -6.497  92.751  1.000 95.276  ? 377 PHE AAA CE1 1 ? 
ATOM   2818 C  CE2 . PHE A 1 377 ? -34.133 -5.193  91.762  1.000 93.985  ? 377 PHE AAA CE2 1 ? 
ATOM   2819 C  CZ  . PHE A 1 377 ? -33.477 -6.395  91.892  1.000 94.680  ? 377 PHE AAA CZ  1 ? 
ATOM   2820 N  N   . LYS A 1 378 ? -31.455 -1.410  96.910  1.000 99.564  ? 378 LYS AAA N   1 ? 
ATOM   2821 C  CA  . LYS A 1 378 ? -31.027 -0.140  97.565  1.000 103.533 ? 378 LYS AAA CA  1 ? 
ATOM   2822 C  C   . LYS A 1 378 ? -29.530 -0.129  97.908  1.000 105.668 ? 378 LYS AAA C   1 ? 
ATOM   2823 O  O   . LYS A 1 378 ? -28.780 0.812   97.572  1.000 104.643 ? 378 LYS AAA O   1 ? 
ATOM   2824 C  CB  . LYS A 1 378 ? -31.861 0.118   98.825  1.000 101.823 ? 378 LYS AAA CB  1 ? 
ATOM   2825 N  N   . PRO A 1 379 ? -29.040 -1.171  98.608  1.000 106.713 ? 379 PRO AAA N   1 ? 
ATOM   2826 C  CA  . PRO A 1 379 ? -27.610 -1.241  98.909  1.000 105.435 ? 379 PRO AAA CA  1 ? 
ATOM   2827 C  C   . PRO A 1 379 ? -26.740 -1.104  97.652  1.000 104.006 ? 379 PRO AAA C   1 ? 
ATOM   2828 O  O   . PRO A 1 379 ? -25.904 -0.177  97.556  1.000 98.489  ? 379 PRO AAA O   1 ? 
ATOM   2829 C  CB  . PRO A 1 379 ? -27.428 -2.632  99.544  1.000 105.039 ? 379 PRO AAA CB  1 ? 
ATOM   2830 C  CG  . PRO A 1 379 ? -28.803 -3.006  100.070 1.000 104.415 ? 379 PRO AAA CG  1 ? 
ATOM   2831 C  CD  . PRO A 1 379 ? -29.799 -2.298  99.174  1.000 105.129 ? 379 PRO AAA CD  1 ? 
ATOM   2832 N  N   . LEU A 1 380 ? -27.011 -1.996  96.694  1.000 108.434 ? 380 LEU AAA N   1 ? 
ATOM   2833 C  CA  . LEU A 1 380 ? -26.225 -2.169  95.448  1.000 113.894 ? 380 LEU AAA CA  1 ? 
ATOM   2834 C  C   . LEU A 1 380 ? -26.236 -0.885  94.646  1.000 110.365 ? 380 LEU AAA C   1 ? 
ATOM   2835 O  O   . LEU A 1 380 ? -25.234 -0.558  93.997  1.000 115.501 ? 380 LEU AAA O   1 ? 
ATOM   2836 C  CB  . LEU A 1 380 ? -26.801 -3.323  94.616  1.000 121.990 ? 380 LEU AAA CB  1 ? 
ATOM   2837 C  CG  . LEU A 1 380 ? -26.480 -4.742  95.094  1.000 129.771 ? 380 LEU AAA CG  1 ? 
ATOM   2838 C  CD1 . LEU A 1 380 ? -27.074 -5.771  94.143  1.000 131.809 ? 380 LEU AAA CD1 1 ? 
ATOM   2839 C  CD2 . LEU A 1 380 ? -24.980 -4.971  95.231  1.000 133.897 ? 380 LEU AAA CD2 1 ? 
ATOM   2840 N  N   . VAL A 1 381 ? -27.349 -0.181  94.710  1.000 102.746 ? 381 VAL AAA N   1 ? 
ATOM   2841 C  CA  . VAL A 1 381 ? -27.454 1.139   94.069  1.000 100.202 ? 381 VAL AAA CA  1 ? 
ATOM   2842 C  C   . VAL A 1 381 ? -26.643 2.172   94.854  1.000 105.399 ? 381 VAL AAA C   1 ? 
ATOM   2843 O  O   . VAL A 1 381 ? -25.873 2.938   94.244  1.000 106.437 ? 381 VAL AAA O   1 ? 
ATOM   2844 C  CB  . VAL A 1 381 ? -28.926 1.563   93.904  1.000 93.100  ? 381 VAL AAA CB  1 ? 
ATOM   2845 C  CG1 . VAL A 1 381 ? -29.056 3.026   93.513  1.000 93.494  ? 381 VAL AAA CG1 1 ? 
ATOM   2846 C  CG2 . VAL A 1 381 ? -29.643 0.678   92.895  1.000 89.615  ? 381 VAL AAA CG2 1 ? 
ATOM   2847 N  N   . GLU A 1 382 ? -26.775 2.190   96.175  1.000 112.954 ? 382 GLU AAA N   1 ? 
ATOM   2848 C  CA  . GLU A 1 382 ? -26.202 3.298   96.985  1.000 123.066 ? 382 GLU AAA CA  1 ? 
ATOM   2849 C  C   . GLU A 1 382 ? -24.667 3.266   97.030  1.000 124.772 ? 382 GLU AAA C   1 ? 
ATOM   2850 O  O   . GLU A 1 382 ? -23.965 4.330   96.864  1.000 132.779 ? 382 GLU AAA O   1 ? 
ATOM   2851 C  CB  . GLU A 1 382 ? -26.820 3.314   98.383  1.000 132.596 ? 382 GLU AAA CB  1 ? 
ATOM   2852 C  CG  . GLU A 1 382 ? -28.218 3.911   98.390  1.000 140.366 ? 382 GLU AAA CG  1 ? 
ATOM   2853 C  CD  . GLU A 1 382 ? -29.011 3.740   99.675  1.000 146.604 ? 382 GLU AAA CD  1 ? 
ATOM   2854 O  OE1 . GLU A 1 382 ? -30.186 4.159   99.700  1.000 149.062 ? 382 GLU AAA OE1 1 ? 
ATOM   2855 O  OE2 . GLU A 1 382 ? -28.457 3.190   100.648 1.000 154.847 ? 382 GLU AAA OE2 1 ? 
ATOM   2856 N  N   . GLU A 1 383 ? -24.164 2.059   97.248  1.000 121.875 ? 383 GLU AAA N   1 ? 
ATOM   2857 C  CA  . GLU A 1 383 ? -22.713 1.807   97.371  1.000 115.196 ? 383 GLU AAA CA  1 ? 
ATOM   2858 C  C   . GLU A 1 383 ? -21.947 2.602   96.308  1.000 110.017 ? 383 GLU AAA C   1 ? 
ATOM   2859 O  O   . GLU A 1 383 ? -20.975 3.284   96.648  1.000 110.324 ? 383 GLU AAA O   1 ? 
ATOM   2860 C  CB  . GLU A 1 383 ? -22.458 0.296   97.364  1.000 115.656 ? 383 GLU AAA CB  1 ? 
ATOM   2861 C  CG  . GLU A 1 383 ? -21.024 -0.090  97.672  1.000 118.706 ? 383 GLU AAA CG  1 ? 
ATOM   2862 C  CD  . GLU A 1 383 ? -20.066 -0.001  96.498  1.000 122.664 ? 383 GLU AAA CD  1 ? 
ATOM   2863 O  OE1 . GLU A 1 383 ? -20.546 0.067   95.350  1.000 124.408 ? 383 GLU AAA OE1 1 ? 
ATOM   2864 O  OE2 . GLU A 1 383 ? -18.838 -0.005  96.737  1.000 125.798 ? 383 GLU AAA OE2 1 ? 
ATOM   2865 N  N   . PRO A 1 384 ? -22.335 2.528   95.009  1.000 106.638 ? 384 PRO AAA N   1 ? 
ATOM   2866 C  CA  . PRO A 1 384 ? -21.744 3.384   93.975  1.000 108.932 ? 384 PRO AAA CA  1 ? 
ATOM   2867 C  C   . PRO A 1 384 ? -22.005 4.882   94.141  1.000 113.993 ? 384 PRO AAA C   1 ? 
ATOM   2868 O  O   . PRO A 1 384 ? -21.070 5.665   94.107  1.000 113.114 ? 384 PRO AAA O   1 ? 
ATOM   2869 C  CB  . PRO A 1 384 ? -22.424 2.938   92.671  1.000 107.435 ? 384 PRO AAA CB  1 ? 
ATOM   2870 C  CG  . PRO A 1 384 ? -22.903 1.535   92.952  1.000 107.349 ? 384 PRO AAA CG  1 ? 
ATOM   2871 C  CD  . PRO A 1 384 ? -23.225 1.513   94.430  1.000 107.062 ? 384 PRO AAA CD  1 ? 
ATOM   2872 N  N   . GLN A 1 385 ? -23.260 5.270   94.318  1.000 124.278 ? 385 GLN AAA N   1 ? 
ATOM   2873 C  CA  . GLN A 1 385 ? -23.607 6.702   94.443  1.000 132.364 ? 385 GLN AAA CA  1 ? 
ATOM   2874 C  C   . GLN A 1 385 ? -22.712 7.370   95.468  1.000 125.904 ? 385 GLN AAA C   1 ? 
ATOM   2875 O  O   . GLN A 1 385 ? -22.097 8.380   95.154  1.000 127.956 ? 385 GLN AAA O   1 ? 
ATOM   2876 C  CB  . GLN A 1 385 ? -25.090 6.874   94.787  1.000 145.998 ? 385 GLN AAA CB  1 ? 
ATOM   2877 C  CG  . GLN A 1 385 ? -25.959 7.159   93.564  1.000 153.198 ? 385 GLN AAA CG  1 ? 
ATOM   2878 C  CD  . GLN A 1 385 ? -27.330 6.526   93.606  1.000 156.134 ? 385 GLN AAA CD  1 ? 
ATOM   2879 O  OE1 . GLN A 1 385 ? -28.053 6.518   92.611  1.000 149.696 ? 385 GLN AAA OE1 1 ? 
ATOM   2880 N  NE2 . GLN A 1 385 ? -27.703 5.987   94.757  1.000 163.117 ? 385 GLN AAA NE2 1 ? 
ATOM   2881 N  N   . ASN A 1 386 ? -22.648 6.820   96.664  1.000 124.074 ? 386 ASN AAA N   1 ? 
ATOM   2882 C  CA  . ASN A 1 386 ? -21.797 7.475   97.680  1.000 124.735 ? 386 ASN AAA CA  1 ? 
ATOM   2883 C  C   . ASN A 1 386 ? -20.384 7.729   97.146  1.000 124.182 ? 386 ASN AAA C   1 ? 
ATOM   2884 O  O   . ASN A 1 386 ? -19.901 8.898   97.034  1.000 127.967 ? 386 ASN AAA O   1 ? 
ATOM   2885 C  CB  . ASN A 1 386 ? -21.688 6.643   98.960  1.000 129.181 ? 386 ASN AAA CB  1 ? 
ATOM   2886 C  CG  . ASN A 1 386 ? -22.843 6.863   99.912  1.000 135.869 ? 386 ASN AAA CG  1 ? 
ATOM   2887 O  OD1 . ASN A 1 386 ? -22.967 7.936   100.499 1.000 133.698 ? 386 ASN AAA OD1 1 ? 
ATOM   2888 N  ND2 . ASN A 1 386 ? -23.677 5.849   100.086 1.000 143.580 ? 386 ASN AAA ND2 1 ? 
ATOM   2889 N  N   . LEU A 1 387 ? -19.754 6.612   96.812  1.000 126.580 ? 387 LEU AAA N   1 ? 
ATOM   2890 C  CA  . LEU A 1 387 ? -18.348 6.551   96.373  1.000 128.561 ? 387 LEU AAA CA  1 ? 
ATOM   2891 C  C   . LEU A 1 387 ? -18.072 7.645   95.365  1.000 120.845 ? 387 LEU AAA C   1 ? 
ATOM   2892 O  O   . LEU A 1 387 ? -17.045 8.311   95.479  1.000 114.057 ? 387 LEU AAA O   1 ? 
ATOM   2893 C  CB  . LEU A 1 387 ? -18.024 5.170   95.791  1.000 138.429 ? 387 LEU AAA CB  1 ? 
ATOM   2894 C  CG  . LEU A 1 387 ? -16.580 4.984   95.315  1.000 140.585 ? 387 LEU AAA CG  1 ? 
ATOM   2895 C  CD1 . LEU A 1 387 ? -15.985 3.686   95.842  1.000 140.270 ? 387 LEU AAA CD1 1 ? 
ATOM   2896 C  CD2 . LEU A 1 387 ? -16.487 5.039   93.796  1.000 140.492 ? 387 LEU AAA CD2 1 ? 
ATOM   2897 N  N   . ILE A 1 388 ? -18.983 7.842   94.426  1.000 117.875 ? 388 ILE AAA N   1 ? 
ATOM   2898 C  CA  . ILE A 1 388 ? -18.787 8.881   93.392  1.000 116.054 ? 388 ILE AAA CA  1 ? 
ATOM   2899 C  C   . ILE A 1 388 ? -18.916 10.284  93.987  1.000 112.782 ? 388 ILE AAA C   1 ? 
ATOM   2900 O  O   . ILE A 1 388 ? -18.047 11.139  93.731  1.000 102.653 ? 388 ILE AAA O   1 ? 
ATOM   2901 C  CB  . ILE A 1 388 ? -19.775 8.718   92.216  1.000 122.534 ? 388 ILE AAA CB  1 ? 
ATOM   2902 C  CG1 . ILE A 1 388 ? -19.768 7.306   91.621  1.000 128.459 ? 388 ILE AAA CG1 1 ? 
ATOM   2903 C  CG2 . ILE A 1 388 ? -19.501 9.769   91.150  1.000 125.393 ? 388 ILE AAA CG2 1 ? 
ATOM   2904 C  CD1 . ILE A 1 388 ? -18.423 6.857   91.095  1.000 136.728 ? 388 ILE AAA CD1 1 ? 
ATOM   2905 N  N   . LYS A 1 389 ? -19.985 10.513  94.746  1.000 120.224 ? 389 LYS AAA N   1 ? 
ATOM   2906 C  CA  . LYS A 1 389 ? -20.206 11.810  95.416  1.000 120.555 ? 389 LYS AAA CA  1 ? 
ATOM   2907 C  C   . LYS A 1 389 ? -18.893 12.183  96.062  1.000 119.054 ? 389 LYS AAA C   1 ? 
ATOM   2908 O  O   . LYS A 1 389 ? -18.371 13.284  95.817  1.000 119.172 ? 389 LYS AAA O   1 ? 
ATOM   2909 C  CB  . LYS A 1 389 ? -21.320 11.730  96.465  1.000 123.528 ? 389 LYS AAA CB  1 ? 
ATOM   2910 C  CG  . LYS A 1 389 ? -21.564 13.012  97.249  1.000 122.081 ? 389 LYS AAA CG  1 ? 
ATOM   2911 N  N   . GLN A 1 390 ? -18.347 11.231  96.803  1.000 123.938 ? 390 GLN AAA N   1 ? 
ATOM   2912 C  CA  . GLN A 1 390 ? -17.182 11.524  97.657  1.000 131.116 ? 390 GLN AAA CA  1 ? 
ATOM   2913 C  C   . GLN A 1 390 ? -15.904 11.891  96.897  1.000 132.301 ? 390 GLN AAA C   1 ? 
ATOM   2914 O  O   . GLN A 1 390 ? -15.300 12.947  97.154  1.000 121.087 ? 390 GLN AAA O   1 ? 
ATOM   2915 C  CB  . GLN A 1 390 ? -16.947 10.355  98.610  1.000 135.037 ? 390 GLN AAA CB  1 ? 
ATOM   2916 C  CG  . GLN A 1 390 ? -18.042 10.243  99.658  1.000 140.796 ? 390 GLN AAA CG  1 ? 
ATOM   2917 C  CD  . GLN A 1 390 ? -17.726 9.197   100.695 1.000 146.428 ? 390 GLN AAA CD  1 ? 
ATOM   2918 O  OE1 . GLN A 1 390 ? -17.480 8.036   100.374 1.000 151.555 ? 390 GLN AAA OE1 1 ? 
ATOM   2919 N  NE2 . GLN A 1 390 ? -17.734 9.608   101.954 1.000 148.666 ? 390 GLN AAA NE2 1 ? 
ATOM   2920 N  N   . ASN A 1 391 ? -15.482 11.047  95.978  1.000 142.622 ? 391 ASN AAA N   1 ? 
ATOM   2921 C  CA  . ASN A 1 391 ? -14.247 11.334  95.213  1.000 148.625 ? 391 ASN AAA CA  1 ? 
ATOM   2922 C  C   . ASN A 1 391 ? -14.453 12.427  94.158  1.000 145.634 ? 391 ASN AAA C   1 ? 
ATOM   2923 O  O   . ASN A 1 391 ? -13.465 12.907  93.589  1.000 148.815 ? 391 ASN AAA O   1 ? 
ATOM   2924 C  CB  . ASN A 1 391 ? -13.651 10.066  94.586  1.000 154.329 ? 391 ASN AAA CB  1 ? 
ATOM   2925 C  CG  . ASN A 1 391 ? -14.578 9.344   93.629  1.000 160.893 ? 391 ASN AAA CG  1 ? 
ATOM   2926 O  OD1 . ASN A 1 391 ? -15.643 9.847   93.275  1.000 167.315 ? 391 ASN AAA OD1 1 ? 
ATOM   2927 N  ND2 . ASN A 1 391 ? -14.175 8.159   93.197  1.000 161.977 ? 391 ASN AAA ND2 1 ? 
ATOM   2928 N  N   . CYS A 1 392 ? -15.691 12.828  93.882  1.000 142.949 ? 392 CYS AAA N   1 ? 
ATOM   2929 C  CA  . CYS A 1 392 ? -15.923 14.057  93.089  1.000 142.028 ? 392 CYS AAA CA  1 ? 
ATOM   2930 C  C   . CYS A 1 392 ? -15.790 15.284  93.974  1.000 143.184 ? 392 CYS AAA C   1 ? 
ATOM   2931 O  O   . CYS A 1 392 ? -15.207 16.291  93.535  1.000 136.994 ? 392 CYS AAA O   1 ? 
ATOM   2932 C  CB  . CYS A 1 392 ? -17.274 14.031  92.380  1.000 143.026 ? 392 CYS AAA CB  1 ? 
ATOM   2933 S  SG  . CYS A 1 392 ? -17.273 13.047  90.856  1.000 144.578 ? 392 CYS AAA SG  1 ? 
ATOM   2934 N  N   . GLU A 1 393 ? -16.327 15.225  95.186  1.000 153.748 ? 393 GLU AAA N   1 ? 
ATOM   2935 C  CA  . GLU A 1 393 ? -15.972 16.253  96.179  1.000 159.582 ? 393 GLU AAA CA  1 ? 
ATOM   2936 C  C   . GLU A 1 393 ? -14.444 16.345  96.213  1.000 154.780 ? 393 GLU AAA C   1 ? 
ATOM   2937 O  O   . GLU A 1 393 ? -13.854 17.435  96.055  1.000 155.054 ? 393 GLU AAA O   1 ? 
ATOM   2938 C  CB  . GLU A 1 393 ? -16.501 15.896  97.574  1.000 163.456 ? 393 GLU AAA CB  1 ? 
ATOM   2939 C  CG  . GLU A 1 393 ? -17.990 16.136  97.768  1.000 161.094 ? 393 GLU AAA CG  1 ? 
ATOM   2940 C  CD  . GLU A 1 393 ? -18.570 15.550  99.048  1.000 154.315 ? 393 GLU AAA CD  1 ? 
ATOM   2941 O  OE1 . GLU A 1 393 ? -17.793 15.011  99.863  1.000 152.536 ? 393 GLU AAA OE1 1 ? 
ATOM   2942 O  OE2 . GLU A 1 393 ? -19.800 15.629  99.226  1.000 145.068 ? 393 GLU AAA OE2 1 ? 
ATOM   2943 N  N   . LEU A 1 394 ? -13.811 15.192  96.386  1.000 146.834 ? 394 LEU AAA N   1 ? 
ATOM   2944 C  CA  . LEU A 1 394 ? -12.342 15.140  96.503  1.000 145.599 ? 394 LEU AAA CA  1 ? 
ATOM   2945 C  C   . LEU A 1 394 ? -11.684 15.754  95.278  1.000 135.180 ? 394 LEU AAA C   1 ? 
ATOM   2946 O  O   . LEU A 1 394 ? -10.843 16.644  95.386  1.000 119.993 ? 394 LEU AAA O   1 ? 
ATOM   2947 C  CB  . LEU A 1 394 ? -11.875 13.698  96.727  1.000 155.382 ? 394 LEU AAA CB  1 ? 
ATOM   2948 C  CG  . LEU A 1 394 ? -10.549 13.561  97.478  1.000 157.801 ? 394 LEU AAA CG  1 ? 
ATOM   2949 C  CD1 . LEU A 1 394 ? -10.762 13.697  98.979  1.000 157.981 ? 394 LEU AAA CD1 1 ? 
ATOM   2950 C  CD2 . LEU A 1 394 ? -9.865  12.240  97.155  1.000 159.983 ? 394 LEU AAA CD2 1 ? 
ATOM   2951 N  N   . PHE A 1 395 ? -12.078 15.275  94.121  1.000 136.807 ? 395 PHE AAA N   1 ? 
ATOM   2952 C  CA  . PHE A 1 395 ? -11.471 15.734  92.869  1.000 139.412 ? 395 PHE AAA CA  1 ? 
ATOM   2953 C  C   . PHE A 1 395 ? -11.477 17.250  92.854  1.000 135.926 ? 395 PHE AAA C   1 ? 
ATOM   2954 O  O   . PHE A 1 395 ? -10.418 17.853  92.801  1.000 125.930 ? 395 PHE AAA O   1 ? 
ATOM   2955 C  CB  . PHE A 1 395 ? -12.208 15.184  91.645  1.000 147.478 ? 395 PHE AAA CB  1 ? 
ATOM   2956 C  CG  . PHE A 1 395 ? -11.773 15.792  90.335  1.000 150.918 ? 395 PHE AAA CG  1 ? 
ATOM   2957 C  CD1 . PHE A 1 395 ? -10.649 15.328  89.669  1.000 148.607 ? 395 PHE AAA CD1 1 ? 
ATOM   2958 C  CD2 . PHE A 1 395 ? -12.482 16.844  89.775  1.000 158.292 ? 395 PHE AAA CD2 1 ? 
ATOM   2959 C  CE1 . PHE A 1 395 ? -10.252 15.891  88.465  1.000 150.447 ? 395 PHE AAA CE1 1 ? 
ATOM   2960 C  CE2 . PHE A 1 395 ? -12.080 17.411  88.575  1.000 160.543 ? 395 PHE AAA CE2 1 ? 
ATOM   2961 C  CZ  . PHE A 1 395 ? -10.967 16.933  87.922  1.000 156.161 ? 395 PHE AAA CZ  1 ? 
ATOM   2962 N  N   . GLU A 1 396 ? -12.656 17.852  92.920  1.000 143.557 ? 396 GLU AAA N   1 ? 
ATOM   2963 C  CA  . GLU A 1 396 ? -12.762 19.324  92.854  1.000 147.270 ? 396 GLU AAA CA  1 ? 
ATOM   2964 C  C   . GLU A 1 396 ? -11.906 19.963  93.950  1.000 139.549 ? 396 GLU AAA C   1 ? 
ATOM   2965 O  O   . GLU A 1 396 ? -11.362 21.066  93.732  1.000 127.691 ? 396 GLU AAA O   1 ? 
ATOM   2966 C  CB  . GLU A 1 396 ? -14.239 19.734  92.944  1.000 155.110 ? 396 GLU AAA CB  1 ? 
ATOM   2967 C  CG  . GLU A 1 396 ? -15.047 19.390  91.696  1.000 153.971 ? 396 GLU AAA CG  1 ? 
ATOM   2968 C  CD  . GLU A 1 396 ? -16.537 19.153  91.897  1.000 150.285 ? 396 GLU AAA CD  1 ? 
ATOM   2969 O  OE1 . GLU A 1 396 ? -17.211 20.037  92.470  1.000 147.107 ? 396 GLU AAA OE1 1 ? 
ATOM   2970 O  OE2 . GLU A 1 396 ? -17.024 18.082  91.471  1.000 142.488 ? 396 GLU AAA OE2 1 ? 
ATOM   2971 N  N   . GLN A 1 397 ? -11.768 19.268  95.078  1.000 136.566 ? 397 GLN AAA N   1 ? 
ATOM   2972 C  CA  . GLN A 1 397 ? -10.978 19.755  96.229  1.000 136.437 ? 397 GLN AAA CA  1 ? 
ATOM   2973 C  C   . GLN A 1 397 ? -9.473  19.600  96.034  1.000 136.049 ? 397 GLN AAA C   1 ? 
ATOM   2974 O  O   . GLN A 1 397 ? -8.730  20.147  96.852  1.000 138.370 ? 397 GLN AAA O   1 ? 
ATOM   2975 C  CB  . GLN A 1 397 ? -11.437 19.030  97.499  1.000 137.792 ? 397 GLN AAA CB  1 ? 
ATOM   2976 C  CG  . GLN A 1 397 ? -10.666 19.408  98.757  1.000 138.981 ? 397 GLN AAA CG  1 ? 
ATOM   2977 C  CD  . GLN A 1 397 ? -11.275 18.814  100.002 1.000 147.851 ? 397 GLN AAA CD  1 ? 
ATOM   2978 O  OE1 . GLN A 1 397 ? -12.004 17.824  99.954  1.000 157.714 ? 397 GLN AAA OE1 1 ? 
ATOM   2979 N  NE2 . GLN A 1 397 ? -10.966 19.414  101.139 1.000 154.752 ? 397 GLN AAA NE2 1 ? 
ATOM   2980 N  N   . LEU A 1 398 ? -9.016  18.882  94.994  1.000 130.048 ? 398 LEU AAA N   1 ? 
ATOM   2981 C  CA  . LEU A 1 398 ? -7.556  18.620  94.777  1.000 118.286 ? 398 LEU AAA CA  1 ? 
ATOM   2982 C  C   . LEU A 1 398 ? -7.019  18.973  93.378  1.000 109.824 ? 398 LEU AAA C   1 ? 
ATOM   2983 O  O   . LEU A 1 398 ? -5.804  19.231  93.256  1.000 97.450  ? 398 LEU AAA O   1 ? 
ATOM   2984 C  CB  . LEU A 1 398 ? -7.267  17.134  95.027  1.000 116.691 ? 398 LEU AAA CB  1 ? 
ATOM   2985 C  CG  . LEU A 1 398 ? -7.270  16.659  96.479  1.000 113.141 ? 398 LEU AAA CG  1 ? 
ATOM   2986 C  CD1 . LEU A 1 398 ? -6.909  15.183  96.549  1.000 111.220 ? 398 LEU AAA CD1 1 ? 
ATOM   2987 C  CD2 . LEU A 1 398 ? -6.313  17.473  97.334  1.000 111.685 ? 398 LEU AAA CD2 1 ? 
ATOM   2988 N  N   . GLY A 1 399 ? -7.863  18.883  92.355  1.000 108.133 ? 399 GLY AAA N   1 ? 
ATOM   2989 C  CA  . GLY A 1 399 ? -7.435  18.962  90.960  1.000 107.256 ? 399 GLY AAA CA  1 ? 
ATOM   2990 C  C   . GLY A 1 399 ? -6.812  17.661  90.521  1.000 107.433 ? 399 GLY AAA C   1 ? 
ATOM   2991 O  O   . GLY A 1 399 ? -6.355  16.873  91.366  1.000 99.950  ? 399 GLY AAA O   1 ? 
ATOM   2992 N  N   . GLU A 1 400 ? -6.764  17.450  89.212  1.000 118.523 ? 400 GLU AAA N   1 ? 
ATOM   2993 C  CA  . GLU A 1 400 ? -6.475  16.120  88.606  1.000 127.376 ? 400 GLU AAA CA  1 ? 
ATOM   2994 C  C   . GLU A 1 400 ? -5.109  15.558  89.038  1.000 124.544 ? 400 GLU AAA C   1 ? 
ATOM   2995 O  O   . GLU A 1 400 ? -5.050  14.433  89.554  1.000 131.548 ? 400 GLU AAA O   1 ? 
ATOM   2996 C  CB  . GLU A 1 400 ? -6.568  16.221  87.084  1.000 136.269 ? 400 GLU AAA CB  1 ? 
ATOM   2997 C  CG  . GLU A 1 400 ? -6.417  14.888  86.382  1.000 145.857 ? 400 GLU AAA CG  1 ? 
ATOM   2998 C  CD  . GLU A 1 400 ? -7.214  14.791  85.095  1.000 154.177 ? 400 GLU AAA CD  1 ? 
ATOM   2999 O  OE1 . GLU A 1 400 ? -8.392  14.404  85.175  1.000 156.232 ? 400 GLU AAA OE1 1 ? 
ATOM   3000 O  OE2 . GLU A 1 400 ? -6.665  15.130  84.028  1.000 166.751 ? 400 GLU AAA OE2 1 ? 
ATOM   3001 N  N   . TYR A 1 401 ? -4.015  16.283  88.824  1.000 119.997 ? 401 TYR AAA N   1 ? 
ATOM   3002 C  CA  . TYR A 1 401 ? -2.677  15.722  89.154  1.000 117.329 ? 401 TYR AAA CA  1 ? 
ATOM   3003 C  C   . TYR A 1 401 ? -2.627  15.251  90.608  1.000 108.439 ? 401 TYR AAA C   1 ? 
ATOM   3004 O  O   . TYR A 1 401 ? -2.369  14.068  90.890  1.000 106.330 ? 401 TYR AAA O   1 ? 
ATOM   3005 C  CB  . TYR A 1 401 ? -1.541  16.705  88.862  1.000 122.418 ? 401 TYR AAA CB  1 ? 
ATOM   3006 C  CG  . TYR A 1 401 ? -0.244  16.326  89.535  1.000 128.505 ? 401 TYR AAA CG  1 ? 
ATOM   3007 C  CD1 . TYR A 1 401 ? 0.509   15.248  89.094  1.000 130.686 ? 401 TYR AAA CD1 1 ? 
ATOM   3008 C  CD2 . TYR A 1 401 ? 0.210   17.015  90.649  1.000 132.965 ? 401 TYR AAA CD2 1 ? 
ATOM   3009 C  CE1 . TYR A 1 401 ? 1.691   14.884  89.723  1.000 131.293 ? 401 TYR AAA CE1 1 ? 
ATOM   3010 C  CE2 . TYR A 1 401 ? 1.387   16.664  91.290  1.000 133.391 ? 401 TYR AAA CE2 1 ? 
ATOM   3011 C  CZ  . TYR A 1 401 ? 2.133   15.595  90.827  1.000 131.361 ? 401 TYR AAA CZ  1 ? 
ATOM   3012 O  OH  . TYR A 1 401 ? 3.290   15.257  91.469  1.000 124.086 ? 401 TYR AAA OH  1 ? 
ATOM   3013 N  N   . LYS A 1 402 ? -2.868  16.163  91.534  1.000 97.889  ? 402 LYS AAA N   1 ? 
ATOM   3014 C  CA  . LYS A 1 402 ? -2.809  15.822  92.961  1.000 90.914  ? 402 LYS AAA CA  1 ? 
ATOM   3015 C  C   . LYS A 1 402 ? -3.770  14.665  93.177  1.000 88.788  ? 402 LYS AAA C   1 ? 
ATOM   3016 O  O   . LYS A 1 402 ? -3.394  13.670  93.802  1.000 86.280  ? 402 LYS AAA O   1 ? 
ATOM   3017 C  CB  . LYS A 1 402 ? -3.188  17.021  93.833  1.000 92.897  ? 402 LYS AAA CB  1 ? 
ATOM   3018 N  N   . PHE A 1 403 ? -4.970  14.781  92.623  1.000 91.341  ? 403 PHE AAA N   1 ? 
ATOM   3019 C  CA  . PHE A 1 403 ? -5.986  13.712  92.726  1.000 93.208  ? 403 PHE AAA CA  1 ? 
ATOM   3020 C  C   . PHE A 1 403 ? -5.409  12.336  92.376  1.000 88.192  ? 403 PHE AAA C   1 ? 
ATOM   3021 O  O   . PHE A 1 403 ? -5.675  11.357  93.094  1.000 90.482  ? 403 PHE AAA O   1 ? 
ATOM   3022 C  CB  . PHE A 1 403 ? -7.202  14.008  91.844  1.000 99.069  ? 403 PHE AAA CB  1 ? 
ATOM   3023 C  CG  . PHE A 1 403 ? -8.261  12.934  91.853  1.000 100.309 ? 403 PHE AAA CG  1 ? 
ATOM   3024 C  CD1 . PHE A 1 403 ? -8.767  12.453  93.052  1.000 102.435 ? 403 PHE AAA CD1 1 ? 
ATOM   3025 C  CD2 . PHE A 1 403 ? -8.761  12.418  90.665  1.000 101.829 ? 403 PHE AAA CD2 1 ? 
ATOM   3026 C  CE1 . PHE A 1 403 ? -9.748  11.474  93.063  1.000 107.801 ? 403 PHE AAA CE1 1 ? 
ATOM   3027 C  CE2 . PHE A 1 403 ? -9.745  11.441  90.677  1.000 106.932 ? 403 PHE AAA CE2 1 ? 
ATOM   3028 C  CZ  . PHE A 1 403 ? -10.236 10.971  91.876  1.000 111.867 ? 403 PHE AAA CZ  1 ? 
ATOM   3029 N  N   . GLN A 1 404 ? -4.636  12.274  91.288  1.000 82.427  ? 404 GLN AAA N   1 ? 
ATOM   3030 C  CA  . GLN A 1 404 ? -3.924  11.043  90.842  1.000 77.344  ? 404 GLN AAA CA  1 ? 
ATOM   3031 C  C   . GLN A 1 404 ? -3.030  10.450  91.925  1.000 75.138  ? 404 GLN AAA C   1 ? 
ATOM   3032 O  O   . GLN A 1 404 ? -2.919  9.223   92.028  1.000 79.139  ? 404 GLN AAA O   1 ? 
ATOM   3033 C  CB  . GLN A 1 404 ? -2.993  11.317  89.659  1.000 74.396  ? 404 GLN AAA CB  1 ? 
ATOM   3034 C  CG  . GLN A 1 404 ? -3.697  11.628  88.347  1.000 74.530  ? 404 GLN AAA CG  1 ? 
ATOM   3035 C  CD  . GLN A 1 404 ? -2.720  12.128  87.308  1.000 73.418  ? 404 GLN AAA CD  1 ? 
ATOM   3036 O  OE1 . GLN A 1 404 ? -1.814  12.902  87.601  1.000 72.399  ? 404 GLN AAA OE1 1 ? 
ATOM   3037 N  NE2 . GLN A 1 404 ? -2.883  11.678  86.076  1.000 74.134  ? 404 GLN AAA NE2 1 ? 
ATOM   3038 N  N   . ASN A 1 405 ? -2.385  11.305  92.702  1.000 72.336  ? 405 ASN AAA N   1 ? 
ATOM   3039 C  CA  . ASN A 1 405 ? -1.442  10.827  93.737  1.000 75.989  ? 405 ASN AAA CA  1 ? 
ATOM   3040 C  C   . ASN A 1 405 ? -2.159  10.135  94.888  1.000 77.139  ? 405 ASN AAA C   1 ? 
ATOM   3041 O  O   . ASN A 1 405 ? -1.630  9.163   95.473  1.000 81.696  ? 405 ASN AAA O   1 ? 
ATOM   3042 C  CB  . ASN A 1 405 ? -0.558  11.954  94.252  1.000 82.716  ? 405 ASN AAA CB  1 ? 
ATOM   3043 C  CG  . ASN A 1 405 ? 0.339   12.463  93.149  1.000 91.771  ? 405 ASN AAA CG  1 ? 
ATOM   3044 O  OD1 . ASN A 1 405 ? 0.202   12.023  92.009  1.000 94.198  ? 405 ASN AAA OD1 1 ? 
ATOM   3045 N  ND2 . ASN A 1 405 ? 1.248   13.372  93.474  1.000 105.045 ? 405 ASN AAA ND2 1 ? 
ATOM   3046 N  N   . ALA A 1 406 ? -3.342  10.619  95.213  1.000 79.965  ? 406 ALA AAA N   1 ? 
ATOM   3047 C  CA  . ALA A 1 406 ? -4.139  10.032  96.295  1.000 82.168  ? 406 ALA AAA CA  1 ? 
ATOM   3048 C  C   . ALA A 1 406 ? -4.551  8.610   95.912  1.000 82.060  ? 406 ALA AAA C   1 ? 
ATOM   3049 O  O   . ALA A 1 406 ? -4.410  7.694   96.733  1.000 85.066  ? 406 ALA AAA O   1 ? 
ATOM   3050 C  CB  . ALA A 1 406 ? -5.349  10.895  96.559  1.000 86.320  ? 406 ALA AAA CB  1 ? 
ATOM   3051 N  N   . LEU A 1 407 ? -5.045  8.443   94.684  1.000 79.673  ? 407 LEU AAA N   1 ? 
ATOM   3052 C  CA  . LEU A 1 407 ? -5.382  7.123   94.107  1.000 76.253  ? 407 LEU AAA CA  1 ? 
ATOM   3053 C  C   . LEU A 1 407 ? -4.124  6.280   94.062  1.000 77.096  ? 407 LEU AAA C   1 ? 
ATOM   3054 O  O   . LEU A 1 407 ? -4.114  5.183   94.595  1.000 79.350  ? 407 LEU AAA O   1 ? 
ATOM   3055 C  CB  . LEU A 1 407 ? -5.956  7.299   92.697  1.000 74.153  ? 407 LEU AAA CB  1 ? 
ATOM   3056 C  CG  . LEU A 1 407 ? -7.299  8.022   92.607  1.000 75.346  ? 407 LEU AAA CG  1 ? 
ATOM   3057 C  CD1 . LEU A 1 407 ? -7.674  8.278   91.158  1.000 75.680  ? 407 LEU AAA CD1 1 ? 
ATOM   3058 C  CD2 . LEU A 1 407 ? -8.397  7.236   93.308  1.000 76.388  ? 407 LEU AAA CD2 1 ? 
ATOM   3059 N  N   . LEU A 1 408 ? -3.085  6.807   93.434  1.000 82.199  ? 408 LEU AAA N   1 ? 
ATOM   3060 C  CA  . LEU A 1 408 ? -1.759  6.159   93.462  1.000 89.521  ? 408 LEU AAA CA  1 ? 
ATOM   3061 C  C   . LEU A 1 408 ? -1.466  5.547   94.823  1.000 88.339  ? 408 LEU AAA C   1 ? 
ATOM   3062 O  O   . LEU A 1 408 ? -1.251  4.335   94.918  1.000 97.079  ? 408 LEU AAA O   1 ? 
ATOM   3063 C  CB  . LEU A 1 408 ? -0.677  7.189   93.130  1.000 99.051  ? 408 LEU AAA CB  1 ? 
ATOM   3064 C  CG  . LEU A 1 408 ? 0.001   7.032   91.774  1.000 106.520 ? 408 LEU AAA CG  1 ? 
ATOM   3065 C  CD1 . LEU A 1 408 ? 1.028   8.131   91.573  1.000 111.333 ? 408 LEU AAA CD1 1 ? 
ATOM   3066 C  CD2 . LEU A 1 408 ? 0.653   5.664   91.647  1.000 106.771 ? 408 LEU AAA CD2 1 ? 
ATOM   3067 N  N   . VAL A 1 409 ? -1.437  6.389   95.845  1.000 86.282  ? 409 VAL AAA N   1 ? 
ATOM   3068 C  CA  . VAL A 1 409 ? -1.079  5.937   97.209  1.000 85.559  ? 409 VAL AAA CA  1 ? 
ATOM   3069 C  C   . VAL A 1 409 ? -2.084  4.898   97.687  1.000 85.154  ? 409 VAL AAA C   1 ? 
ATOM   3070 O  O   . VAL A 1 409 ? -1.682  3.806   98.129  1.000 82.331  ? 409 VAL AAA O   1 ? 
ATOM   3071 C  CB  . VAL A 1 409 ? -0.988  7.108   98.204  1.000 91.756  ? 409 VAL AAA CB  1 ? 
ATOM   3072 C  CG1 . VAL A 1 409 ? -0.836  6.619   99.635  1.000 95.133  ? 409 VAL AAA CG1 1 ? 
ATOM   3073 C  CG2 . VAL A 1 409 ? 0.145   8.059   97.862  1.000 95.094  ? 409 VAL AAA CG2 1 ? 
ATOM   3074 N  N   . ARG A 1 410 ? -3.363  5.244   97.593  1.000 88.439  ? 410 ARG AAA N   1 ? 
ATOM   3075 C  CA  . ARG A 1 410 ? -4.467  4.369   98.048  1.000 91.454  ? 410 ARG AAA CA  1 ? 
ATOM   3076 C  C   . ARG A 1 410 ? -4.184  2.978   97.507  1.000 86.168  ? 410 ARG AAA C   1 ? 
ATOM   3077 O  O   . ARG A 1 410 ? -4.026  2.029   98.273  1.000 84.163  ? 410 ARG AAA O   1 ? 
ATOM   3078 C  CB  . ARG A 1 410 ? -5.833  4.896   97.576  1.000 100.460 ? 410 ARG AAA CB  1 ? 
ATOM   3079 C  CG  . ARG A 1 410 ? -7.032  4.481   98.425  1.000 109.039 ? 410 ARG AAA CG  1 ? 
ATOM   3080 C  CD  . ARG A 1 410 ? -7.594  5.595   99.311  1.000 118.097 ? 410 ARG AAA CD  1 ? 
ATOM   3081 N  NE  . ARG A 1 410 ? -8.708  5.176   100.168 1.000 125.136 ? 410 ARG AAA NE  1 ? 
ATOM   3082 C  CZ  . ARG A 1 410 ? -9.356  5.955   101.045 1.000 120.081 ? 410 ARG AAA CZ  1 ? 
ATOM   3083 N  NH1 . ARG A 1 410 ? -9.021  7.226   101.197 1.000 114.679 ? 410 ARG AAA NH1 1 ? 
ATOM   3084 N  NH2 . ARG A 1 410 ? -10.347 5.454   101.767 1.000 117.772 ? 410 ARG AAA NH2 1 ? 
ATOM   3085 N  N   . TYR A 1 411 ? -4.062  2.893   96.196  1.000 83.198  ? 411 TYR AAA N   1 ? 
ATOM   3086 C  CA  . TYR A 1 411 ? -3.931  1.608   95.485  1.000 80.434  ? 411 TYR AAA CA  1 ? 
ATOM   3087 C  C   . TYR A 1 411 ? -2.604  0.904   95.744  1.000 76.554  ? 411 TYR AAA C   1 ? 
ATOM   3088 O  O   . TYR A 1 411 ? -2.565  -0.307  96.024  1.000 79.494  ? 411 TYR AAA O   1 ? 
ATOM   3089 C  CB  . TYR A 1 411 ? -4.207  1.799   93.991  1.000 81.198  ? 411 TYR AAA CB  1 ? 
ATOM   3090 C  CG  . TYR A 1 411 ? -5.677  1.759   93.670  1.000 82.676  ? 411 TYR AAA CG  1 ? 
ATOM   3091 C  CD1 . TYR A 1 411 ? -6.499  2.832   93.964  1.000 86.164  ? 411 TYR AAA CD1 1 ? 
ATOM   3092 C  CD2 . TYR A 1 411 ? -6.259  0.624   93.135  1.000 87.792  ? 411 TYR AAA CD2 1 ? 
ATOM   3093 C  CE1 . TYR A 1 411 ? -7.859  2.794   93.700  1.000 93.678  ? 411 TYR AAA CE1 1 ? 
ATOM   3094 C  CE2 . TYR A 1 411 ? -7.617  0.567   92.865  1.000 94.788  ? 411 TYR AAA CE2 1 ? 
ATOM   3095 C  CZ  . TYR A 1 411 ? -8.423  1.657   93.146  1.000 96.544  ? 411 TYR AAA CZ  1 ? 
ATOM   3096 O  OH  . TYR A 1 411 ? -9.766  1.619   92.887  1.000 99.575  ? 411 TYR AAA OH  1 ? 
ATOM   3097 N  N   . THR A 1 412 ? -1.520  1.650   95.661  1.000 71.854  ? 412 THR AAA N   1 ? 
ATOM   3098 C  CA  . THR A 1 412 ? -0.188  1.089   95.919  1.000 68.321  ? 412 THR AAA CA  1 ? 
ATOM   3099 C  C   . THR A 1 412 ? -0.175  0.296   97.216  1.000 69.350  ? 412 THR AAA C   1 ? 
ATOM   3100 O  O   . THR A 1 412 ? 0.462   -0.747  97.272  1.000 69.878  ? 412 THR AAA O   1 ? 
ATOM   3101 C  CB  . THR A 1 412 ? 0.896   2.163   96.011  1.000 67.572  ? 412 THR AAA CB  1 ? 
ATOM   3102 O  OG1 . THR A 1 412 ? 0.828   2.952   94.825  1.000 72.010  ? 412 THR AAA OG1 1 ? 
ATOM   3103 C  CG2 . THR A 1 412 ? 2.279   1.570   96.156  1.000 65.261  ? 412 THR AAA CG2 1 ? 
ATOM   3104 N  N   . LYS A 1 413 ? -0.861  0.816   98.234  1.000 73.971  ? 413 LYS AAA N   1 ? 
ATOM   3105 C  CA  . LYS A 1 413 ? -0.970  0.143   99.558  1.000 80.263  ? 413 LYS AAA CA  1 ? 
ATOM   3106 C  C   . LYS A 1 413 ? -1.853  -1.111  99.521  1.000 85.578  ? 413 LYS AAA C   1 ? 
ATOM   3107 O  O   . LYS A 1 413 ? -1.595  -2.126  100.242 1.000 89.492  ? 413 LYS AAA O   1 ? 
ATOM   3108 C  CB  . LYS A 1 413 ? -1.509  1.119   100.605 1.000 83.631  ? 413 LYS AAA CB  1 ? 
ATOM   3109 C  CG  . LYS A 1 413 ? -0.553  2.244   100.969 1.000 87.917  ? 413 LYS AAA CG  1 ? 
ATOM   3110 C  CD  . LYS A 1 413 ? -1.019  3.088   102.135 1.000 90.632  ? 413 LYS AAA CD  1 ? 
ATOM   3111 C  CE  . LYS A 1 413 ? -0.025  4.170   102.502 1.000 92.859  ? 413 LYS AAA CE  1 ? 
ATOM   3112 N  NZ  . LYS A 1 413 ? -0.364  4.821   103.790 1.000 93.845  ? 413 LYS AAA NZ  1 ? 
ATOM   3113 N  N   . LYS A 1 414 ? -2.908  -1.006  98.720  1.000 90.238  ? 414 LYS AAA N   1 ? 
ATOM   3114 C  CA  . LYS A 1 414 ? -3.841  -2.114  98.460  1.000 93.519  ? 414 LYS AAA CA  1 ? 
ATOM   3115 C  C   . LYS A 1 414 ? -3.068  -3.262  97.802  1.000 91.965  ? 414 LYS AAA C   1 ? 
ATOM   3116 O  O   . LYS A 1 414 ? -3.258  -4.421  98.203  1.000 94.008  ? 414 LYS AAA O   1 ? 
ATOM   3117 C  CB  . LYS A 1 414 ? -5.040  -1.625  97.634  1.000 95.648  ? 414 LYS AAA CB  1 ? 
ATOM   3118 C  CG  . LYS A 1 414 ? -5.961  -0.638  98.348  1.000 96.796  ? 414 LYS AAA CG  1 ? 
ATOM   3119 C  CD  . LYS A 1 414 ? -6.753  0.276   97.421  1.000 99.639  ? 414 LYS AAA CD  1 ? 
ATOM   3120 C  CE  . LYS A 1 414 ? -8.190  -0.151  97.204  1.000 102.300 ? 414 LYS AAA CE  1 ? 
ATOM   3121 N  NZ  . LYS A 1 414 ? -9.105  0.439   98.211  1.000 101.771 ? 414 LYS AAA NZ  1 ? 
ATOM   3122 N  N   . VAL A 1 415 ? -2.171  -2.951  96.861  1.000 89.454  ? 415 VAL AAA N   1 ? 
ATOM   3123 C  CA  . VAL A 1 415 ? -1.489  -3.993  96.037  1.000 87.493  ? 415 VAL AAA CA  1 ? 
ATOM   3124 C  C   . VAL A 1 415 ? -0.007  -3.708  95.834  1.000 84.940  ? 415 VAL AAA C   1 ? 
ATOM   3125 O  O   . VAL A 1 415 ? 0.492   -3.726  94.708  1.000 84.819  ? 415 VAL AAA O   1 ? 
ATOM   3126 C  CB  . VAL A 1 415 ? -2.201  -4.169  94.683  1.000 92.112  ? 415 VAL AAA CB  1 ? 
ATOM   3127 C  CG1 . VAL A 1 415 ? -3.566  -4.813  94.853  1.000 93.207  ? 415 VAL AAA CG1 1 ? 
ATOM   3128 C  CG2 . VAL A 1 415 ? -2.320  -2.857  93.917  1.000 95.768  ? 415 VAL AAA CG2 1 ? 
ATOM   3129 N  N   . PRO A 1 416 ? 0.740   -3.529  96.935  1.000 84.642  ? 416 PRO AAA N   1 ? 
ATOM   3130 C  CA  . PRO A 1 416 ? 2.133   -3.127  96.819  1.000 91.021  ? 416 PRO AAA CA  1 ? 
ATOM   3131 C  C   . PRO A 1 416 ? 2.996   -4.084  95.994  1.000 97.441  ? 416 PRO AAA C   1 ? 
ATOM   3132 O  O   . PRO A 1 416 ? 4.156   -3.800  95.710  1.000 101.266 ? 416 PRO AAA O   1 ? 
ATOM   3133 C  CB  . PRO A 1 416 ? 2.658   -3.124  98.264  1.000 89.697  ? 416 PRO AAA CB  1 ? 
ATOM   3134 C  CG  . PRO A 1 416 ? 1.439   -3.290  99.152  1.000 87.080  ? 416 PRO AAA CG  1 ? 
ATOM   3135 C  CD  . PRO A 1 416 ? 0.378   -3.941  98.296  1.000 84.509  ? 416 PRO AAA CD  1 ? 
ATOM   3136 N  N   . GLN A 1 417 ? 2.412   -5.211  95.624  1.000 105.323 ? 417 GLN AAA N   1 ? 
ATOM   3137 C  CA  . GLN A 1 417 ? 3.124   -6.219  94.838  1.000 109.570 ? 417 GLN AAA CA  1 ? 
ATOM   3138 C  C   . GLN A 1 417 ? 3.154   -5.827  93.366  1.000 104.793 ? 417 GLN AAA C   1 ? 
ATOM   3139 O  O   . GLN A 1 417 ? 4.060   -6.285  92.665  1.000 98.370  ? 417 GLN AAA O   1 ? 
ATOM   3140 C  CB  . GLN A 1 417 ? 2.502   -7.606  95.020  1.000 118.991 ? 417 GLN AAA CB  1 ? 
ATOM   3141 C  CG  . GLN A 1 417 ? 2.632   -8.169  96.431  1.000 125.396 ? 417 GLN AAA CG  1 ? 
ATOM   3142 C  CD  . GLN A 1 417 ? 1.589   -7.643  97.387  1.000 139.340 ? 417 GLN AAA CD  1 ? 
ATOM   3143 O  OE1 . GLN A 1 417 ? 0.533   -7.152  96.989  1.000 155.719 ? 417 GLN AAA OE1 1 ? 
ATOM   3144 N  NE2 . GLN A 1 417 ? 1.885   -7.743  98.673  1.000 145.279 ? 417 GLN AAA NE2 1 ? 
ATOM   3145 N  N   . VAL A 1 418 ? 2.214   -5.004  92.906  1.000 104.474 ? 418 VAL AAA N   1 ? 
ATOM   3146 C  CA  . VAL A 1 418 ? 2.120   -4.664  91.455  1.000 104.264 ? 418 VAL AAA CA  1 ? 
ATOM   3147 C  C   . VAL A 1 418 ? 3.279   -3.771  91.019  1.000 106.327 ? 418 VAL AAA C   1 ? 
ATOM   3148 O  O   . VAL A 1 418 ? 3.656   -2.818  91.737  1.000 111.366 ? 418 VAL AAA O   1 ? 
ATOM   3149 C  CB  . VAL A 1 418 ? 0.778   -4.000  91.090  1.000 106.020 ? 418 VAL AAA CB  1 ? 
ATOM   3150 C  CG1 . VAL A 1 418 ? 0.732   -3.602  89.618  1.000 106.179 ? 418 VAL AAA CG1 1 ? 
ATOM   3151 C  CG2 . VAL A 1 418 ? -0.409  -4.886  91.436  1.000 106.519 ? 418 VAL AAA CG2 1 ? 
ATOM   3152 N  N   . SER A 1 419 ? 3.769   -4.026  89.812  1.000 104.772 ? 419 SER AAA N   1 ? 
ATOM   3153 C  CA  . SER A 1 419 ? 4.854   -3.241  89.194  1.000 102.722 ? 419 SER AAA CA  1 ? 
ATOM   3154 C  C   . SER A 1 419 ? 4.544   -1.759  89.209  1.000 97.410  ? 419 SER AAA C   1 ? 
ATOM   3155 O  O   . SER A 1 419 ? 3.395   -1.334  88.924  1.000 103.127 ? 419 SER AAA O   1 ? 
ATOM   3156 C  CB  . SER A 1 419 ? 5.112   -3.737  87.789  1.000 103.000 ? 419 SER AAA CB  1 ? 
ATOM   3157 O  OG  . SER A 1 419 ? 3.902   -3.828  87.045  1.000 98.841  ? 419 SER AAA OG  1 ? 
ATOM   3158 N  N   . THR A 1 420 ? 5.582   -0.989  89.470  1.000 89.053  ? 420 THR AAA N   1 ? 
ATOM   3159 C  CA  . THR A 1 420 ? 5.479   0.468   89.551  1.000 89.662  ? 420 THR AAA CA  1 ? 
ATOM   3160 C  C   . THR A 1 420 ? 4.844   1.031   88.274  1.000 90.429  ? 420 THR AAA C   1 ? 
ATOM   3161 O  O   . THR A 1 420 ? 3.831   1.720   88.354  1.000 95.836  ? 420 THR AAA O   1 ? 
ATOM   3162 C  CB  . THR A 1 420 ? 6.853   1.096   89.826  1.000 90.687  ? 420 THR AAA CB  1 ? 
ATOM   3163 O  OG1 . THR A 1 420 ? 7.380   0.459   90.989  1.000 92.968  ? 420 THR AAA OG1 1 ? 
ATOM   3164 C  CG2 . THR A 1 420 ? 6.798   2.596   90.024  1.000 92.053  ? 420 THR AAA CG2 1 ? 
ATOM   3165 N  N   . PRO A 1 421 ? 5.394   0.734   87.068  1.000 85.844  ? 421 PRO AAA N   1 ? 
ATOM   3166 C  CA  . PRO A 1 421 ? 4.896   1.344   85.829  1.000 82.593  ? 421 PRO AAA CA  1 ? 
ATOM   3167 C  C   . PRO A 1 421 ? 3.394   1.165   85.651  1.000 76.435  ? 421 PRO AAA C   1 ? 
ATOM   3168 O  O   . PRO A 1 421 ? 2.670   2.099   85.270  1.000 73.975  ? 421 PRO AAA O   1 ? 
ATOM   3169 C  CB  . PRO A 1 421 ? 5.661   0.611   84.716  1.000 84.235  ? 421 PRO AAA CB  1 ? 
ATOM   3170 C  CG  . PRO A 1 421 ? 6.895   0.057   85.400  1.000 83.581  ? 421 PRO AAA CG  1 ? 
ATOM   3171 C  CD  . PRO A 1 421 ? 6.454   -0.254  86.813  1.000 84.299  ? 421 PRO AAA CD  1 ? 
ATOM   3172 N  N   . THR A 1 422 ? 2.963   -0.050  85.925  1.000 73.032  ? 422 THR AAA N   1 ? 
ATOM   3173 C  CA  . THR A 1 422 ? 1.540   -0.382  85.962  1.000 73.331  ? 422 THR AAA CA  1 ? 
ATOM   3174 C  C   . THR A 1 422 ? 0.831   0.436   87.028  1.000 69.766  ? 422 THR AAA C   1 ? 
ATOM   3175 O  O   . THR A 1 422 ? -0.229  1.014   86.769  1.000 68.468  ? 422 THR AAA O   1 ? 
ATOM   3176 C  CB  . THR A 1 422 ? 1.368   -1.890  86.186  1.000 76.108  ? 422 THR AAA CB  1 ? 
ATOM   3177 O  OG1 . THR A 1 422 ? 2.258   -2.557  85.286  1.000 76.595  ? 422 THR AAA OG1 1 ? 
ATOM   3178 C  CG2 . THR A 1 422 ? -0.055  -2.358  85.974  1.000 77.010  ? 422 THR AAA CG2 1 ? 
ATOM   3179 N  N   . LEU A 1 423 ? 1.385   0.484   88.218  1.000 68.643  ? 423 LEU AAA N   1 ? 
ATOM   3180 C  CA  . LEU A 1 423 ? 0.677   1.236   89.252  1.000 69.635  ? 423 LEU AAA CA  1 ? 
ATOM   3181 C  C   . LEU A 1 423 ? 0.475   2.659   88.761  1.000 70.789  ? 423 LEU AAA C   1 ? 
ATOM   3182 O  O   . LEU A 1 423 ? -0.662  3.103   88.633  1.000 73.303  ? 423 LEU AAA O   1 ? 
ATOM   3183 C  CB  . LEU A 1 423 ? 1.410   1.144   90.589  1.000 71.780  ? 423 LEU AAA CB  1 ? 
ATOM   3184 C  CG  . LEU A 1 423 ? 0.987   -0.061  91.428  1.000 74.975  ? 423 LEU AAA CG  1 ? 
ATOM   3185 C  CD1 . LEU A 1 423 ? 2.009   -0.360  92.511  1.000 77.497  ? 423 LEU AAA CD1 1 ? 
ATOM   3186 C  CD2 . LEU A 1 423 ? -0.395  0.146   92.038  1.000 74.382  ? 423 LEU AAA CD2 1 ? 
ATOM   3187 N  N   . VAL A 1 424 ? 1.555   3.326   88.422  1.000 72.683  ? 424 VAL AAA N   1 ? 
ATOM   3188 C  CA  . VAL A 1 424 ? 1.476   4.687   87.857  1.000 77.890  ? 424 VAL AAA CA  1 ? 
ATOM   3189 C  C   . VAL A 1 424 ? 0.419   4.758   86.771  1.000 81.601  ? 424 VAL AAA C   1 ? 
ATOM   3190 O  O   . VAL A 1 424 ? -0.592  5.468   86.920  1.000 78.953  ? 424 VAL AAA O   1 ? 
ATOM   3191 C  CB  . VAL A 1 424 ? 2.832   5.157   87.295  1.000 80.749  ? 424 VAL AAA CB  1 ? 
ATOM   3192 C  CG1 . VAL A 1 424 ? 2.698   6.483   86.555  1.000 81.136  ? 424 VAL AAA CG1 1 ? 
ATOM   3193 C  CG2 . VAL A 1 424 ? 3.900   5.248   88.375  1.000 82.144  ? 424 VAL AAA CG2 1 ? 
ATOM   3194 N  N   . GLU A 1 425 ? 0.668   4.020   85.703  1.000 88.993  ? 425 GLU AAA N   1 ? 
ATOM   3195 C  CA  . GLU A 1 425 ? -0.215  4.025   84.523  1.000 92.474  ? 425 GLU AAA CA  1 ? 
ATOM   3196 C  C   . GLU A 1 425 ? -1.676  3.920   84.929  1.000 86.813  ? 425 GLU AAA C   1 ? 
ATOM   3197 O  O   . GLU A 1 425 ? -2.505  4.706   84.448  1.000 85.475  ? 425 GLU AAA O   1 ? 
ATOM   3198 C  CB  . GLU A 1 425 ? 0.147   2.893   83.560  1.000 102.636 ? 425 GLU AAA CB  1 ? 
ATOM   3199 C  CG  . GLU A 1 425 ? -0.538  3.016   82.211  1.000 111.602 ? 425 GLU AAA CG  1 ? 
ATOM   3200 C  CD  . GLU A 1 425 ? -0.367  4.374   81.547  1.000 121.834 ? 425 GLU AAA CD  1 ? 
ATOM   3201 O  OE1 . GLU A 1 425 ? 0.754   4.932   81.607  1.000 130.259 ? 425 GLU AAA OE1 1 ? 
ATOM   3202 O  OE2 . GLU A 1 425 ? -1.358  4.882   80.986  1.000 129.509 ? 425 GLU AAA OE2 1 ? 
ATOM   3203 N  N   . VAL A 1 426 ? -1.989  2.950   85.767  1.000 83.872  ? 426 VAL AAA N   1 ? 
ATOM   3204 C  CA  . VAL A 1 426 ? -3.394  2.704   86.155  1.000 84.085  ? 426 VAL AAA CA  1 ? 
ATOM   3205 C  C   . VAL A 1 426 ? -3.897  3.854   87.006  1.000 84.879  ? 426 VAL AAA C   1 ? 
ATOM   3206 O  O   . VAL A 1 426 ? -4.880  4.517   86.651  1.000 88.725  ? 426 VAL AAA O   1 ? 
ATOM   3207 C  CB  . VAL A 1 426 ? -3.541  1.356   86.886  1.000 85.045  ? 426 VAL AAA CB  1 ? 
ATOM   3208 C  CG1 . VAL A 1 426 ? -4.818  1.275   87.713  1.000 82.683  ? 426 VAL AAA CG1 1 ? 
ATOM   3209 C  CG2 . VAL A 1 426 ? -3.463  0.196   85.905  1.000 89.283  ? 426 VAL AAA CG2 1 ? 
ATOM   3210 N  N   . SER A 1 427 ? -3.221  4.099   88.107  1.000 84.426  ? 427 SER AAA N   1 ? 
ATOM   3211 C  CA  . SER A 1 427 ? -3.537  5.248   88.976  1.000 83.743  ? 427 SER AAA CA  1 ? 
ATOM   3212 C  C   . SER A 1 427 ? -3.902  6.481   88.148  1.000 81.570  ? 427 SER AAA C   1 ? 
ATOM   3213 O  O   . SER A 1 427 ? -4.999  7.041   88.296  1.000 77.258  ? 427 SER AAA O   1 ? 
ATOM   3214 C  CB  . SER A 1 427 ? -2.398  5.543   89.904  1.000 84.649  ? 427 SER AAA CB  1 ? 
ATOM   3215 O  OG  . SER A 1 427 ? -2.032  4.375   90.623  1.000 87.751  ? 427 SER AAA OG  1 ? 
ATOM   3216 N  N   . ARG A 1 428 ? -2.984  6.896   87.289  1.000 86.864  ? 428 ARG AAA N   1 ? 
ATOM   3217 C  CA  . ARG A 1 428 ? -3.194  8.124   86.501  1.000 94.002  ? 428 ARG AAA CA  1 ? 
ATOM   3218 C  C   . ARG A 1 428 ? -4.538  8.062   85.781  1.000 94.264  ? 428 ARG AAA C   1 ? 
ATOM   3219 O  O   . ARG A 1 428 ? -5.296  9.046   85.797  1.000 105.298 ? 428 ARG AAA O   1 ? 
ATOM   3220 C  CB  . ARG A 1 428 ? -2.046  8.333   85.506  1.000 97.750  ? 428 ARG AAA CB  1 ? 
ATOM   3221 C  CG  . ARG A 1 428 ? -0.688  8.570   86.152  1.000 96.585  ? 428 ARG AAA CG  1 ? 
ATOM   3222 C  CD  . ARG A 1 428 ? 0.346   9.095   85.173  1.000 94.976  ? 428 ARG AAA CD  1 ? 
ATOM   3223 N  NE  . ARG A 1 428 ? 0.466   10.549  85.233  1.000 93.119  ? 428 ARG AAA NE  1 ? 
ATOM   3224 C  CZ  . ARG A 1 428 ? 0.187   11.401  84.246  1.000 93.955  ? 428 ARG AAA CZ  1 ? 
ATOM   3225 N  NH1 . ARG A 1 428 ? -0.239  10.969  83.070  1.000 96.097  ? 428 ARG AAA NH1 1 ? 
ATOM   3226 N  NH2 . ARG A 1 428 ? 0.350   12.699  84.436  1.000 94.717  ? 428 ARG AAA NH2 1 ? 
ATOM   3227 N  N   . ASN A 1 429 ? -4.836  6.909   85.200  1.000 87.023  ? 429 ASN AAA N   1 ? 
ATOM   3228 C  CA  . ASN A 1 429 ? -6.089  6.720   84.444  1.000 82.542  ? 429 ASN AAA CA  1 ? 
ATOM   3229 C  C   . ASN A 1 429 ? -7.321  6.673   85.322  1.000 80.089  ? 429 ASN AAA C   1 ? 
ATOM   3230 O  O   . ASN A 1 429 ? -8.386  7.146   84.917  1.000 83.788  ? 429 ASN AAA O   1 ? 
ATOM   3231 C  CB  . ASN A 1 429 ? -6.001  5.480   83.560  1.000 84.537  ? 429 ASN AAA CB  1 ? 
ATOM   3232 C  CG  . ASN A 1 429 ? -4.888  5.608   82.544  1.000 87.703  ? 429 ASN AAA CG  1 ? 
ATOM   3233 O  OD1 . ASN A 1 429 ? -4.566  6.717   82.120  1.000 85.588  ? 429 ASN AAA OD1 1 ? 
ATOM   3234 N  ND2 . ASN A 1 429 ? -4.278  4.493   82.174  1.000 93.848  ? 429 ASN AAA ND2 1 ? 
ATOM   3235 N  N   . LEU A 1 430 ? -7.170  6.111   86.500  1.000 78.936  ? 430 LEU AAA N   1 ? 
ATOM   3236 C  CA  . LEU A 1 430 ? -8.207  6.257   87.514  1.000 83.000  ? 430 LEU AAA CA  1 ? 
ATOM   3237 C  C   . LEU A 1 430 ? -8.416  7.752   87.733  1.000 84.752  ? 430 LEU AAA C   1 ? 
ATOM   3238 O  O   . LEU A 1 430 ? -9.560  8.206   87.823  1.000 89.391  ? 430 LEU AAA O   1 ? 
ATOM   3239 C  CB  . LEU A 1 430 ? -7.813  5.538   88.809  1.000 87.314  ? 430 LEU AAA CB  1 ? 
ATOM   3240 C  CG  . LEU A 1 430 ? -7.747  4.013   88.727  1.000 93.601  ? 430 LEU AAA CG  1 ? 
ATOM   3241 C  CD1 . LEU A 1 430 ? -7.192  3.417   90.013  1.000 94.557  ? 430 LEU AAA CD1 1 ? 
ATOM   3242 C  CD2 . LEU A 1 430 ? -9.114  3.420   88.421  1.000 95.630  ? 430 LEU AAA CD2 1 ? 
ATOM   3243 N  N   . GLY A 1 431 ? -7.324  8.506   87.764  1.000 84.792  ? 431 GLY AAA N   1 ? 
ATOM   3244 C  CA  . GLY A 1 431 ? -7.354  9.956   88.004  1.000 80.266  ? 431 GLY AAA CA  1 ? 
ATOM   3245 C  C   . GLY A 1 431 ? -8.283  10.706  87.083  1.000 77.949  ? 431 GLY AAA C   1 ? 
ATOM   3246 O  O   . GLY A 1 431 ? -9.056  11.557  87.540  1.000 72.281  ? 431 GLY AAA O   1 ? 
ATOM   3247 N  N   . LYS A 1 432 ? -8.216  10.400  85.802  1.000 82.498  ? 432 LYS AAA N   1 ? 
ATOM   3248 C  CA  . LYS A 1 432 ? -9.043  11.112  84.801  1.000 87.970  ? 432 LYS AAA CA  1 ? 
ATOM   3249 C  C   . LYS A 1 432 ? -10.541 10.960  85.016  1.000 95.637  ? 432 LYS AAA C   1 ? 
ATOM   3250 O  O   . LYS A 1 432 ? -11.286 11.794  84.514  1.000 98.148  ? 432 LYS AAA O   1 ? 
ATOM   3251 C  CB  . LYS A 1 432 ? -8.667  10.669  83.383  1.000 86.952  ? 432 LYS AAA CB  1 ? 
ATOM   3252 C  CG  . LYS A 1 432 ? -7.315  11.176  82.906  1.000 88.830  ? 432 LYS AAA CG  1 ? 
ATOM   3253 C  CD  . LYS A 1 432 ? -6.676  10.308  81.846  1.000 96.823  ? 432 LYS AAA CD  1 ? 
ATOM   3254 C  CE  . LYS A 1 432 ? -5.245  10.710  81.549  1.000 104.158 ? 432 LYS AAA CE  1 ? 
ATOM   3255 N  NZ  . LYS A 1 432 ? -4.521  9.685   80.759  1.000 107.829 ? 432 LYS AAA NZ  1 ? 
ATOM   3256 N  N   . VAL A 1 433 ? -10.991 9.934   85.717  1.000 104.382 ? 433 VAL AAA N   1 ? 
ATOM   3257 C  CA  . VAL A 1 433 ? -12.433 9.836   86.017  1.000 109.583 ? 433 VAL AAA CA  1 ? 
ATOM   3258 C  C   . VAL A 1 433 ? -12.891 11.224  86.391  1.000 116.388 ? 433 VAL AAA C   1 ? 
ATOM   3259 O  O   . VAL A 1 433 ? -13.866 11.717  85.839  1.000 124.176 ? 433 VAL AAA O   1 ? 
ATOM   3260 C  CB  . VAL A 1 433 ? -12.741 8.870   87.179  1.000 109.559 ? 433 VAL AAA CB  1 ? 
ATOM   3261 C  CG1 . VAL A 1 433 ? -14.022 9.241   87.920  1.000 108.321 ? 433 VAL AAA CG1 1 ? 
ATOM   3262 C  CG2 . VAL A 1 433 ? -12.815 7.432   86.713  1.000 110.567 ? 433 VAL AAA CG2 1 ? 
ATOM   3263 N  N   . GLY A 1 434 ? -12.199 11.801  87.357  1.000 117.276 ? 434 GLY AAA N   1 ? 
ATOM   3264 C  CA  . GLY A 1 434 ? -12.639 13.053  87.969  1.000 117.844 ? 434 GLY AAA CA  1 ? 
ATOM   3265 C  C   . GLY A 1 434 ? -12.949 14.081  86.919  1.000 120.198 ? 434 GLY AAA C   1 ? 
ATOM   3266 O  O   . GLY A 1 434 ? -14.101 14.546  86.797  1.000 128.000 ? 434 GLY AAA O   1 ? 
ATOM   3267 N  N   . SER A 1 435 ? -11.937 14.407  86.138  1.000 111.441 ? 435 SER AAA N   1 ? 
ATOM   3268 C  CA  . SER A 1 435 ? -12.103 15.447  85.112  1.000 105.868 ? 435 SER AAA CA  1 ? 
ATOM   3269 C  C   . SER A 1 435 ? -13.120 15.029  84.058  1.000 110.287 ? 435 SER AAA C   1 ? 
ATOM   3270 O  O   . SER A 1 435 ? -13.955 15.859  83.661  1.000 112.725 ? 435 SER AAA O   1 ? 
ATOM   3271 C  CB  . SER A 1 435 ? -10.788 15.812  84.498  1.000 99.701  ? 435 SER AAA CB  1 ? 
ATOM   3272 O  OG  . SER A 1 435 ? -10.195 14.674  83.905  1.000 101.242 ? 435 SER AAA OG  1 ? 
ATOM   3273 N  N   . LYS A 1 436 ? -13.081 13.763  83.656  1.000 115.389 ? 436 LYS AAA N   1 ? 
ATOM   3274 C  CA  . LYS A 1 436 ? -14.019 13.210  82.650  1.000 119.423 ? 436 LYS AAA CA  1 ? 
ATOM   3275 C  C   . LYS A 1 436 ? -15.468 13.424  83.073  1.000 121.536 ? 436 LYS AAA C   1 ? 
ATOM   3276 O  O   . LYS A 1 436 ? -16.282 13.924  82.284  1.000 122.705 ? 436 LYS AAA O   1 ? 
ATOM   3277 C  CB  . LYS A 1 436 ? -13.738 11.717  82.434  1.000 119.010 ? 436 LYS AAA CB  1 ? 
ATOM   3278 C  CG  . LYS A 1 436 ? -14.527 11.058  81.309  1.000 117.213 ? 436 LYS AAA CG  1 ? 
ATOM   3279 N  N   . CYS A 1 437 ? -15.781 13.052  84.303  1.000 122.291 ? 437 CYS AAA N   1 ? 
ATOM   3280 C  CA  . CYS A 1 437 ? -17.161 12.786  84.730  1.000 128.869 ? 437 CYS AAA CA  1 ? 
ATOM   3281 C  C   . CYS A 1 437 ? -17.675 13.816  85.713  1.000 138.329 ? 437 CYS AAA C   1 ? 
ATOM   3282 O  O   . CYS A 1 437 ? -18.833 14.222  85.603  1.000 155.394 ? 437 CYS AAA O   1 ? 
ATOM   3283 C  CB  . CYS A 1 437 ? -17.272 11.410  85.374  1.000 131.500 ? 437 CYS AAA CB  1 ? 
ATOM   3284 S  SG  . CYS A 1 437 ? -16.849 10.053  84.250  1.000 140.372 ? 437 CYS AAA SG  1 ? 
ATOM   3285 N  N   . CYS A 1 438 ? -16.872 14.188  86.703  1.000 143.691 ? 438 CYS AAA N   1 ? 
ATOM   3286 C  CA  . CYS A 1 438 ? -17.389 14.989  87.836  1.000 151.700 ? 438 CYS AAA CA  1 ? 
ATOM   3287 C  C   . CYS A 1 438 ? -18.084 16.288  87.381  1.000 159.018 ? 438 CYS AAA C   1 ? 
ATOM   3288 O  O   . CYS A 1 438 ? -18.902 16.821  88.158  1.000 149.084 ? 438 CYS AAA O   1 ? 
ATOM   3289 C  CB  . CYS A 1 438 ? -16.309 15.263  88.879  1.000 147.993 ? 438 CYS AAA CB  1 ? 
ATOM   3290 S  SG  . CYS A 1 438 ? -15.718 13.767  89.723  1.000 148.565 ? 438 CYS AAA SG  1 ? 
ATOM   3291 N  N   . LYS A 1 439 ? -17.809 16.783  86.173  1.000 173.110 ? 439 LYS AAA N   1 ? 
ATOM   3292 C  CA  . LYS A 1 439 ? -18.483 17.991  85.616  1.000 181.960 ? 439 LYS AAA CA  1 ? 
ATOM   3293 C  C   . LYS A 1 439 ? -19.950 17.764  85.245  1.000 188.347 ? 439 LYS AAA C   1 ? 
ATOM   3294 O  O   . LYS A 1 439 ? -20.744 18.737  85.151  1.000 196.083 ? 439 LYS AAA O   1 ? 
ATOM   3295 C  CB  . LYS A 1 439 ? -17.725 18.501  84.384  1.000 181.682 ? 439 LYS AAA CB  1 ? 
ATOM   3296 C  CG  . LYS A 1 439 ? -17.797 17.604  83.154  1.000 188.492 ? 439 LYS AAA CG  1 ? 
ATOM   3297 C  CD  . LYS A 1 439 ? -16.886 18.043  82.029  1.000 192.085 ? 439 LYS AAA CD  1 ? 
ATOM   3298 C  CE  . LYS A 1 439 ? -16.922 17.102  80.842  1.000 191.192 ? 439 LYS AAA CE  1 ? 
ATOM   3299 N  NZ  . LYS A 1 439 ? -16.632 17.811  79.574  1.000 189.043 ? 439 LYS AAA NZ  1 ? 
ATOM   3300 N  N   . HIS A 1 440 ? -20.317 16.518  85.020  1.000 188.691 ? 440 HIS AAA N   1 ? 
ATOM   3301 C  CA  . HIS A 1 440 ? -21.707 16.169  84.695  1.000 186.153 ? 440 HIS AAA CA  1 ? 
ATOM   3302 C  C   . HIS A 1 440 ? -22.587 16.334  85.941  1.000 192.149 ? 440 HIS AAA C   1 ? 
ATOM   3303 O  O   . HIS A 1 440 ? -22.086 16.367  87.071  1.000 177.555 ? 440 HIS AAA O   1 ? 
ATOM   3304 C  CB  . HIS A 1 440 ? -21.803 14.741  84.134  1.000 179.127 ? 440 HIS AAA CB  1 ? 
ATOM   3305 C  CG  . HIS A 1 440 ? -21.129 14.554  82.816  1.000 169.389 ? 440 HIS AAA CG  1 ? 
ATOM   3306 N  ND1 . HIS A 1 440 ? -21.369 15.380  81.734  1.000 160.880 ? 440 HIS AAA ND1 1 ? 
ATOM   3307 C  CD2 . HIS A 1 440 ? -20.240 13.628  82.395  1.000 166.295 ? 440 HIS AAA CD2 1 ? 
ATOM   3308 C  CE1 . HIS A 1 440 ? -20.647 14.976  80.708  1.000 158.048 ? 440 HIS AAA CE1 1 ? 
ATOM   3309 N  NE2 . HIS A 1 440 ? -19.947 13.903  81.087  1.000 162.124 ? 440 HIS AAA NE2 1 ? 
ATOM   3310 N  N   . PRO A 1 441 ? -23.922 16.464  85.750  1.000 205.118 ? 441 PRO AAA N   1 ? 
ATOM   3311 C  CA  . PRO A 1 441 ? -24.905 16.332  86.841  1.000 209.718 ? 441 PRO AAA CA  1 ? 
ATOM   3312 C  C   . PRO A 1 441 ? -24.965 14.899  87.377  1.000 211.932 ? 441 PRO AAA C   1 ? 
ATOM   3313 O  O   . PRO A 1 441 ? -24.780 13.958  86.609  1.000 213.634 ? 441 PRO AAA O   1 ? 
ATOM   3314 C  CB  . PRO A 1 441 ? -26.267 16.686  86.215  1.000 206.719 ? 441 PRO AAA CB  1 ? 
ATOM   3315 C  CG  . PRO A 1 441 ? -25.972 17.163  84.800  1.000 203.838 ? 441 PRO AAA CG  1 ? 
ATOM   3316 C  CD  . PRO A 1 441 ? -24.578 16.682  84.451  1.000 205.232 ? 441 PRO AAA CD  1 ? 
ATOM   3317 N  N   . GLU A 1 442 ? -25.282 14.738  88.658  1.000 211.279 ? 442 GLU AAA N   1 ? 
ATOM   3318 C  CA  . GLU A 1 442 ? -25.420 13.391  89.270  1.000 215.298 ? 442 GLU AAA CA  1 ? 
ATOM   3319 C  C   . GLU A 1 442 ? -26.050 12.399  88.282  1.000 229.558 ? 442 GLU AAA C   1 ? 
ATOM   3320 O  O   . GLU A 1 442 ? -25.486 11.311  88.045  1.000 253.193 ? 442 GLU AAA O   1 ? 
ATOM   3321 C  CB  . GLU A 1 442 ? -26.253 13.469  90.552  1.000 204.561 ? 442 GLU AAA CB  1 ? 
ATOM   3322 N  N   . ALA A 1 443 ? -27.173 12.769  87.678  1.000 238.063 ? 443 ALA AAA N   1 ? 
ATOM   3323 C  CA  . ALA A 1 443 ? -27.920 11.907  86.729  1.000 240.679 ? 443 ALA AAA CA  1 ? 
ATOM   3324 C  C   . ALA A 1 443 ? -27.035 11.154  85.734  1.000 230.984 ? 443 ALA AAA C   1 ? 
ATOM   3325 O  O   . ALA A 1 443 ? -27.358 10.019  85.358  1.000 220.610 ? 443 ALA AAA O   1 ? 
ATOM   3326 C  CB  . ALA A 1 443 ? -28.933 12.738  85.985  1.000 248.074 ? 443 ALA AAA CB  1 ? 
ATOM   3327 N  N   . LYS A 1 444 ? -25.967 11.796  85.286  1.000 224.315 ? 444 LYS AAA N   1 ? 
ATOM   3328 C  CA  . LYS A 1 444 ? -25.084 11.243  84.247  1.000 224.974 ? 444 LYS AAA CA  1 ? 
ATOM   3329 C  C   . LYS A 1 444 ? -23.716 10.842  84.791  1.000 226.209 ? 444 LYS AAA C   1 ? 
ATOM   3330 O  O   . LYS A 1 444 ? -22.873 10.356  84.010  1.000 246.111 ? 444 LYS AAA O   1 ? 
ATOM   3331 C  CB  . LYS A 1 444 ? -24.942 12.270  83.119  1.000 224.122 ? 444 LYS AAA CB  1 ? 
ATOM   3332 C  CG  . LYS A 1 444 ? -26.255 12.695  82.474  1.000 227.672 ? 444 LYS AAA CG  1 ? 
ATOM   3333 C  CD  . LYS A 1 444 ? -26.098 13.771  81.424  1.000 231.396 ? 444 LYS AAA CD  1 ? 
ATOM   3334 C  CE  . LYS A 1 444 ? -27.418 14.200  80.819  1.000 232.182 ? 444 LYS AAA CE  1 ? 
ATOM   3335 N  NZ  . LYS A 1 444 ? -27.241 15.312  79.856  1.000 232.843 ? 444 LYS AAA NZ  1 ? 
ATOM   3336 N  N   . ARG A 1 445 ? -23.498 11.001  86.095  1.000 216.310 ? 445 ARG AAA N   1 ? 
ATOM   3337 C  CA  . ARG A 1 445 ? -22.176 10.707  86.707  1.000 204.608 ? 445 ARG AAA CA  1 ? 
ATOM   3338 C  C   . ARG A 1 445 ? -21.858 9.205   86.729  1.000 203.574 ? 445 ARG AAA C   1 ? 
ATOM   3339 O  O   . ARG A 1 445 ? -20.913 8.787   86.081  1.000 203.709 ? 445 ARG AAA O   1 ? 
ATOM   3340 C  CB  . ARG A 1 445 ? -22.086 11.274  88.130  1.000 198.023 ? 445 ARG AAA CB  1 ? 
ATOM   3341 C  CG  . ARG A 1 445 ? -21.803 12.769  88.199  1.000 192.656 ? 445 ARG AAA CG  1 ? 
ATOM   3342 C  CD  . ARG A 1 445 ? -21.502 13.212  89.619  1.000 187.603 ? 445 ARG AAA CD  1 ? 
ATOM   3343 N  NE  . ARG A 1 445 ? -20.985 14.572  89.700  1.000 185.037 ? 445 ARG AAA NE  1 ? 
ATOM   3344 C  CZ  . ARG A 1 445 ? -20.489 15.133  90.802  1.000 184.242 ? 445 ARG AAA CZ  1 ? 
ATOM   3345 N  NH1 . ARG A 1 445 ? -20.436 14.454  91.937  1.000 176.871 ? 445 ARG AAA NH1 1 ? 
ATOM   3346 N  NH2 . ARG A 1 445 ? -20.043 16.377  90.761  1.000 186.836 ? 445 ARG AAA NH2 1 ? 
ATOM   3347 N  N   . MET A 1 446 ? -22.618 8.401   87.468  1.000 204.814 ? 446 MET AAA N   1 ? 
ATOM   3348 C  CA  . MET A 1 446 ? -22.284 6.972   87.716  1.000 208.788 ? 446 MET AAA CA  1 ? 
ATOM   3349 C  C   . MET A 1 446 ? -22.007 6.182   86.435  1.000 215.279 ? 446 MET AAA C   1 ? 
ATOM   3350 O  O   . MET A 1 446 ? -21.006 5.457   86.377  1.000 225.865 ? 446 MET AAA O   1 ? 
ATOM   3351 C  CB  . MET A 1 446 ? -23.406 6.286   88.506  1.000 205.749 ? 446 MET AAA CB  1 ? 
ATOM   3352 C  CG  . MET A 1 446 ? -23.075 4.866   88.933  1.000 203.505 ? 446 MET AAA CG  1 ? 
ATOM   3353 S  SD  . MET A 1 446 ? -24.547 3.910   89.376  1.000 195.936 ? 446 MET AAA SD  1 ? 
ATOM   3354 C  CE  . MET A 1 446 ? -25.234 4.929   90.679  1.000 189.535 ? 446 MET AAA CE  1 ? 
ATOM   3355 N  N   . PRO A 1 447 ? -22.894 6.219   85.415  1.000 204.625 ? 447 PRO AAA N   1 ? 
ATOM   3356 C  CA  . PRO A 1 447 ? -22.604 5.483   84.186  1.000 190.607 ? 447 PRO AAA CA  1 ? 
ATOM   3357 C  C   . PRO A 1 447 ? -21.317 5.997   83.524  1.000 173.794 ? 447 PRO AAA C   1 ? 
ATOM   3358 O  O   . PRO A 1 447 ? -20.562 5.224   82.948  1.000 183.402 ? 447 PRO AAA O   1 ? 
ATOM   3359 C  CB  . PRO A 1 447 ? -23.843 5.716   83.304  1.000 188.986 ? 447 PRO AAA CB  1 ? 
ATOM   3360 C  CG  . PRO A 1 447 ? -24.472 6.982   83.855  1.000 188.429 ? 447 PRO AAA CG  1 ? 
ATOM   3361 C  CD  . PRO A 1 447 ? -24.153 6.977   85.336  1.000 195.094 ? 447 PRO AAA CD  1 ? 
ATOM   3362 N  N   . CYS A 1 448 ? -21.056 7.294   83.650  1.000 145.142 ? 448 CYS AAA N   1 ? 
ATOM   3363 C  CA  . CYS A 1 448 ? -19.759 7.863   83.233  1.000 127.522 ? 448 CYS AAA CA  1 ? 
ATOM   3364 C  C   . CYS A 1 448 ? -18.620 7.202   83.996  1.000 116.703 ? 448 CYS AAA C   1 ? 
ATOM   3365 O  O   . CYS A 1 448 ? -17.755 6.579   83.388  1.000 114.797 ? 448 CYS AAA O   1 ? 
ATOM   3366 C  CB  . CYS A 1 448 ? -19.712 9.373   83.437  1.000 131.264 ? 448 CYS AAA CB  1 ? 
ATOM   3367 S  SG  . CYS A 1 448 ? -18.229 10.159  82.754  1.000 142.036 ? 448 CYS AAA SG  1 ? 
ATOM   3368 N  N   . ALA A 1 449 ? -18.663 7.328   85.313  1.000 110.692 ? 449 ALA AAA N   1 ? 
ATOM   3369 C  CA  . ALA A 1 449 ? -17.541 7.013   86.207  1.000 111.426 ? 449 ALA AAA CA  1 ? 
ATOM   3370 C  C   . ALA A 1 449 ? -17.332 5.519   86.235  1.000 115.328 ? 449 ALA AAA C   1 ? 
ATOM   3371 O  O   . ALA A 1 449 ? -16.323 5.004   85.733  1.000 128.351 ? 449 ALA AAA O   1 ? 
ATOM   3372 C  CB  . ALA A 1 449 ? -17.811 7.565   87.588  1.000 103.877 ? 449 ALA AAA CB  1 ? 
ATOM   3373 N  N   . GLU A 1 450 ? -18.312 4.847   86.794  1.000 106.334 ? 450 GLU AAA N   1 ? 
ATOM   3374 C  CA  . GLU A 1 450 ? -18.151 3.441   87.148  1.000 102.138 ? 450 GLU AAA CA  1 ? 
ATOM   3375 C  C   . GLU A 1 450 ? -17.726 2.649   85.920  1.000 100.360 ? 450 GLU AAA C   1 ? 
ATOM   3376 O  O   . GLU A 1 450 ? -16.750 1.889   86.012  1.000 103.313 ? 450 GLU AAA O   1 ? 
ATOM   3377 C  CB  . GLU A 1 450 ? -19.440 2.888   87.743  1.000 98.924  ? 450 GLU AAA CB  1 ? 
ATOM   3378 C  CG  . GLU A 1 450 ? -19.287 1.461   88.222  1.000 99.022  ? 450 GLU AAA CG  1 ? 
ATOM   3379 C  CD  . GLU A 1 450 ? -19.919 1.196   89.573  1.000 98.047  ? 450 GLU AAA CD  1 ? 
ATOM   3380 O  OE1 . GLU A 1 450 ? -21.074 1.609   89.775  1.000 101.502 ? 450 GLU AAA OE1 1 ? 
ATOM   3381 O  OE2 . GLU A 1 450 ? -19.245 0.592   90.423  1.000 93.528  ? 450 GLU AAA OE2 1 ? 
ATOM   3382 N  N   . ASP A 1 451 ? -18.423 2.849   84.808  1.000 96.908  ? 451 ASP AAA N   1 ? 
ATOM   3383 C  CA  . ASP A 1 451 ? -18.130 2.114   83.557  1.000 102.406 ? 451 ASP AAA CA  1 ? 
ATOM   3384 C  C   . ASP A 1 451 ? -16.780 2.505   82.953  1.000 99.613  ? 451 ASP AAA C   1 ? 
ATOM   3385 O  O   . ASP A 1 451 ? -16.183 1.696   82.225  1.000 107.462 ? 451 ASP AAA O   1 ? 
ATOM   3386 C  CB  . ASP A 1 451 ? -19.280 2.281   82.561  1.000 111.260 ? 451 ASP AAA CB  1 ? 
ATOM   3387 C  CG  . ASP A 1 451 ? -20.601 1.726   83.073  1.000 121.554 ? 451 ASP AAA CG  1 ? 
ATOM   3388 O  OD1 . ASP A 1 451 ? -20.587 0.600   83.621  1.000 131.185 ? 451 ASP AAA OD1 1 ? 
ATOM   3389 O  OD2 . ASP A 1 451 ? -21.634 2.419   82.929  1.000 127.349 ? 451 ASP AAA OD2 1 ? 
ATOM   3390 N  N   . TYR A 1 452 ? -16.278 3.693   83.254  1.000 91.492  ? 452 TYR AAA N   1 ? 
ATOM   3391 C  CA  . TYR A 1 452 ? -14.916 4.063   82.827  1.000 88.349  ? 452 TYR AAA CA  1 ? 
ATOM   3392 C  C   . TYR A 1 452 ? -13.945 3.291   83.695  1.000 81.405  ? 452 TYR AAA C   1 ? 
ATOM   3393 O  O   . TYR A 1 452 ? -13.015 2.654   83.193  1.000 81.973  ? 452 TYR AAA O   1 ? 
ATOM   3394 C  CB  . TYR A 1 452 ? -14.675 5.565   82.946  1.000 91.316  ? 452 TYR AAA CB  1 ? 
ATOM   3395 C  CG  . TYR A 1 452 ? -13.234 5.940   82.734  1.000 95.725  ? 452 TYR AAA CG  1 ? 
ATOM   3396 C  CD1 . TYR A 1 452 ? -12.701 6.058   81.459  1.000 100.483 ? 452 TYR AAA CD1 1 ? 
ATOM   3397 C  CD2 . TYR A 1 452 ? -12.392 6.130   83.813  1.000 93.047  ? 452 TYR AAA CD2 1 ? 
ATOM   3398 C  CE1 . TYR A 1 452 ? -11.371 6.391   81.262  1.000 100.979 ? 452 TYR AAA CE1 1 ? 
ATOM   3399 C  CE2 . TYR A 1 452 ? -11.062 6.464   83.635  1.000 96.731  ? 452 TYR AAA CE2 1 ? 
ATOM   3400 C  CZ  . TYR A 1 452 ? -10.548 6.595   82.356  1.000 101.559 ? 452 TYR AAA CZ  1 ? 
ATOM   3401 O  OH  . TYR A 1 452 ? -9.235  6.920   82.167  1.000 108.148 ? 452 TYR AAA OH  1 ? 
ATOM   3402 N  N   . LEU A 1 453 ? -14.207 3.330   84.989  1.000 73.155  ? 453 LEU AAA N   1 ? 
ATOM   3403 C  CA  . LEU A 1 453 ? -13.410 2.609   85.984  1.000 69.545  ? 453 LEU AAA CA  1 ? 
ATOM   3404 C  C   . LEU A 1 453 ? -13.340 1.134   85.629  1.000 66.480  ? 453 LEU AAA C   1 ? 
ATOM   3405 O  O   . LEU A 1 453 ? -12.292 0.510   85.799  1.000 68.178  ? 453 LEU AAA O   1 ? 
ATOM   3406 C  CB  . LEU A 1 453 ? -14.025 2.813   87.374  1.000 67.985  ? 453 LEU AAA CB  1 ? 
ATOM   3407 C  CG  . LEU A 1 453 ? -13.861 4.217   87.951  1.000 69.474  ? 453 LEU AAA CG  1 ? 
ATOM   3408 C  CD1 . LEU A 1 453 ? -14.745 4.429   89.169  1.000 67.802  ? 453 LEU AAA CD1 1 ? 
ATOM   3409 C  CD2 . LEU A 1 453 ? -12.407 4.483   88.302  1.000 72.457  ? 453 LEU AAA CD2 1 ? 
ATOM   3410 N  N   . SER A 1 454 ? -14.432 0.597   85.130  1.000 63.893  ? 454 SER AAA N   1 ? 
ATOM   3411 C  CA  . SER A 1 454 ? -14.454 -0.800  84.714  1.000 63.092  ? 454 SER AAA CA  1 ? 
ATOM   3412 C  C   . SER A 1 454 ? -13.496 -1.067  83.568  1.000 60.276  ? 454 SER AAA C   1 ? 
ATOM   3413 O  O   . SER A 1 454 ? -12.924 -2.149  83.539  1.000 63.393  ? 454 SER AAA O   1 ? 
ATOM   3414 C  CB  . SER A 1 454 ? -15.852 -1.274  84.459  1.000 65.729  ? 454 SER AAA CB  1 ? 
ATOM   3415 O  OG  . SER A 1 454 ? -16.521 -1.468  85.703  1.000 66.606  ? 454 SER AAA OG  1 ? 
ATOM   3416 N  N   . VAL A 1 455 ? -13.291 -0.088  82.699  1.000 56.744  ? 455 VAL AAA N   1 ? 
ATOM   3417 C  CA  . VAL A 1 455 ? -12.257 -0.193  81.642  1.000 60.695  ? 455 VAL AAA CA  1 ? 
ATOM   3418 C  C   . VAL A 1 455 ? -10.870 -0.134  82.262  1.000 68.110  ? 455 VAL AAA C   1 ? 
ATOM   3419 O  O   . VAL A 1 455 ? -10.079 -1.073  82.107  1.000 78.000  ? 455 VAL AAA O   1 ? 
ATOM   3420 C  CB  . VAL A 1 455 ? -12.416 0.906   80.576  1.000 59.163  ? 455 VAL AAA CB  1 ? 
ATOM   3421 C  CG1 . VAL A 1 455 ? -11.332 0.817   79.507  1.000 59.120  ? 455 VAL AAA CG1 1 ? 
ATOM   3422 C  CG2 . VAL A 1 455 ? -13.796 0.869   79.945  1.000 59.463  ? 455 VAL AAA CG2 1 ? 
ATOM   3423 N  N   . VAL A 1 456 ? -10.574 0.940   82.976  1.000 73.876  ? 456 VAL AAA N   1 ? 
ATOM   3424 C  CA  . VAL A 1 456 ? -9.236  1.116   83.601  1.000 79.257  ? 456 VAL AAA CA  1 ? 
ATOM   3425 C  C   . VAL A 1 456 ? -8.862  -0.135  84.394  1.000 83.290  ? 456 VAL AAA C   1 ? 
ATOM   3426 O  O   . VAL A 1 456 ? -7.734  -0.669  84.253  1.000 95.506  ? 456 VAL AAA O   1 ? 
ATOM   3427 C  CB  . VAL A 1 456 ? -9.191  2.347   84.530  1.000 79.274  ? 456 VAL AAA CB  1 ? 
ATOM   3428 C  CG1 . VAL A 1 456 ? -7.949  2.337   85.411  1.000 79.200  ? 456 VAL AAA CG1 1 ? 
ATOM   3429 C  CG2 . VAL A 1 456 ? -9.277  3.655   83.762  1.000 82.547  ? 456 VAL AAA CG2 1 ? 
ATOM   3430 N  N   . LEU A 1 457 ? -9.771  -0.580  85.247  1.000 78.518  ? 457 LEU AAA N   1 ? 
ATOM   3431 C  CA  . LEU A 1 457 ? -9.485  -1.753  86.084  1.000 73.538  ? 457 LEU AAA CA  1 ? 
ATOM   3432 C  C   . LEU A 1 457 ? -9.176  -2.965  85.223  1.000 73.000  ? 457 LEU AAA C   1 ? 
ATOM   3433 O  O   . LEU A 1 457 ? -8.291  -3.780  85.572  1.000 70.061  ? 457 LEU AAA O   1 ? 
ATOM   3434 C  CB  . LEU A 1 457 ? -10.633 -2.006  87.064  1.000 72.374  ? 457 LEU AAA CB  1 ? 
ATOM   3435 C  CG  . LEU A 1 457 ? -10.664 -1.040  88.249  1.000 73.576  ? 457 LEU AAA CG  1 ? 
ATOM   3436 C  CD1 . LEU A 1 457 ? -11.944 -1.184  89.051  1.000 74.708  ? 457 LEU AAA CD1 1 ? 
ATOM   3437 C  CD2 . LEU A 1 457 ? -9.458  -1.234  89.152  1.000 72.458  ? 457 LEU AAA CD2 1 ? 
ATOM   3438 N  N   . ASN A 1 458 ? -9.838  -3.052  84.087  1.000 77.819  ? 458 ASN AAA N   1 ? 
ATOM   3439 C  CA  . ASN A 1 458 ? -9.485  -4.114  83.135  1.000 82.207  ? 458 ASN AAA CA  1 ? 
ATOM   3440 C  C   . ASN A 1 458 ? -8.030  -3.962  82.649  1.000 84.816  ? 458 ASN AAA C   1 ? 
ATOM   3441 O  O   . ASN A 1 458 ? -7.341  -4.986  82.544  1.000 89.904  ? 458 ASN AAA O   1 ? 
ATOM   3442 C  CB  . ASN A 1 458 ? -10.448 -4.153  81.941  1.000 83.187  ? 458 ASN AAA CB  1 ? 
ATOM   3443 C  CG  . ASN A 1 458 ? -10.156 -5.262  80.951  1.000 83.141  ? 458 ASN AAA CG  1 ? 
ATOM   3444 O  OD1 . ASN A 1 458 ? -10.381 -6.436  81.240  1.000 81.620  ? 458 ASN AAA OD1 1 ? 
ATOM   3445 N  ND2 . ASN A 1 458 ? -9.681  -4.896  79.769  1.000 82.634  ? 458 ASN AAA ND2 1 ? 
ATOM   3446 N  N   . GLN A 1 459 ? -7.548  -2.739  82.377  1.000 87.007  ? 459 GLN AAA N   1 ? 
ATOM   3447 C  CA  . GLN A 1 459 ? -6.116  -2.543  81.972  1.000 90.625  ? 459 GLN AAA CA  1 ? 
ATOM   3448 C  C   . GLN A 1 459 ? -5.207  -3.141  83.047  1.000 85.054  ? 459 GLN AAA C   1 ? 
ATOM   3449 O  O   . GLN A 1 459 ? -4.227  -3.861  82.752  1.000 86.169  ? 459 GLN AAA O   1 ? 
ATOM   3450 C  CB  . GLN A 1 459 ? -5.770  -1.075  81.699  1.000 99.289  ? 459 GLN AAA CB  1 ? 
ATOM   3451 C  CG  . GLN A 1 459 ? -5.953  -0.652  80.240  1.000 109.537 ? 459 GLN AAA CG  1 ? 
ATOM   3452 C  CD  . GLN A 1 459 ? -4.931  -1.214  79.270  1.000 114.326 ? 459 GLN AAA CD  1 ? 
ATOM   3453 O  OE1 . GLN A 1 459 ? -3.736  -1.298  79.554  1.000 114.268 ? 459 GLN AAA OE1 1 ? 
ATOM   3454 N  NE2 . GLN A 1 459 ? -5.387  -1.581  78.081  1.000 111.823 ? 459 GLN AAA NE2 1 ? 
ATOM   3455 N  N   . LEU A 1 460 ? -5.545  -2.837  84.285  1.000 78.110  ? 460 LEU AAA N   1 ? 
ATOM   3456 C  CA  . LEU A 1 460 ? -4.805  -3.409  85.395  1.000 74.578  ? 460 LEU AAA CA  1 ? 
ATOM   3457 C  C   . LEU A 1 460 ? -4.854  -4.908  85.231  1.000 79.240  ? 460 LEU AAA C   1 ? 
ATOM   3458 O  O   . LEU A 1 460 ? -3.825  -5.556  85.138  1.000 84.207  ? 460 LEU AAA O   1 ? 
ATOM   3459 C  CB  . LEU A 1 460 ? -5.367  -2.996  86.756  1.000 69.135  ? 460 LEU AAA CB  1 ? 
ATOM   3460 C  CG  . LEU A 1 460 ? -4.681  -3.682  87.937  1.000 66.149  ? 460 LEU AAA CG  1 ? 
ATOM   3461 C  CD1 . LEU A 1 460 ? -3.190  -3.397  87.945  1.000 64.297  ? 460 LEU AAA CD1 1 ? 
ATOM   3462 C  CD2 . LEU A 1 460 ? -5.303  -3.259  89.255  1.000 67.418  ? 460 LEU AAA CD2 1 ? 
ATOM   3463 N  N   . CYS A 1 461 ? -6.060  -5.421  85.163  1.000 83.001  ? 461 CYS AAA N   1 ? 
ATOM   3464 C  CA  . CYS A 1 461 ? -6.280  -6.864  85.158  1.000 83.442  ? 461 CYS AAA CA  1 ? 
ATOM   3465 C  C   . CYS A 1 461 ? -5.442  -7.542  84.092  1.000 80.119  ? 461 CYS AAA C   1 ? 
ATOM   3466 O  O   . CYS A 1 461 ? -4.808  -8.544  84.382  1.000 83.827  ? 461 CYS AAA O   1 ? 
ATOM   3467 C  CB  . CYS A 1 461 ? -7.752  -7.212  84.999  1.000 89.280  ? 461 CYS AAA CB  1 ? 
ATOM   3468 S  SG  . CYS A 1 461 ? -8.689  -6.915  86.519  1.000 97.750  ? 461 CYS AAA SG  1 ? 
ATOM   3469 N  N   . VAL A 1 462 ? -5.414  -6.986  82.897  1.000 76.088  ? 462 VAL AAA N   1 ? 
ATOM   3470 C  CA  . VAL A 1 462 ? -4.646  -7.626  81.810  1.000 75.768  ? 462 VAL AAA CA  1 ? 
ATOM   3471 C  C   . VAL A 1 462 ? -3.152  -7.405  81.966  1.000 77.938  ? 462 VAL AAA C   1 ? 
ATOM   3472 O  O   . VAL A 1 462 ? -2.390  -8.346  81.811  1.000 82.032  ? 462 VAL AAA O   1 ? 
ATOM   3473 C  CB  . VAL A 1 462 ? -5.136  -7.209  80.408  1.000 74.972  ? 462 VAL AAA CB  1 ? 
ATOM   3474 C  CG1 . VAL A 1 462 ? -6.612  -7.514  80.219  1.000 74.033  ? 462 VAL AAA CG1 1 ? 
ATOM   3475 C  CG2 . VAL A 1 462 ? -4.841  -5.752  80.081  1.000 76.341  ? 462 VAL AAA CG2 1 ? 
ATOM   3476 N  N   . LEU A 1 463 ? -2.739  -6.193  82.283  1.000 77.623  ? 463 LEU AAA N   1 ? 
ATOM   3477 C  CA  . LEU A 1 463 ? -1.299  -5.940  82.454  1.000 79.324  ? 463 LEU AAA CA  1 ? 
ATOM   3478 C  C   . LEU A 1 463 ? -0.772  -6.895  83.519  1.000 78.101  ? 463 LEU AAA C   1 ? 
ATOM   3479 O  O   . LEU A 1 463 ? 0.361   -7.394  83.430  1.000 85.285  ? 463 LEU AAA O   1 ? 
ATOM   3480 C  CB  . LEU A 1 463 ? -1.073  -4.477  82.853  1.000 80.160  ? 463 LEU AAA CB  1 ? 
ATOM   3481 C  CG  . LEU A 1 463 ? -1.357  -3.434  81.770  1.000 81.475  ? 463 LEU AAA CG  1 ? 
ATOM   3482 C  CD1 . LEU A 1 463 ? -1.195  -2.031  82.327  1.000 82.572  ? 463 LEU AAA CD1 1 ? 
ATOM   3483 C  CD2 . LEU A 1 463 ? -0.459  -3.625  80.558  1.000 82.812  ? 463 LEU AAA CD2 1 ? 
ATOM   3484 N  N   . HIS A 1 464 ? -1.616  -7.145  84.499  1.000 75.992  ? 464 HIS AAA N   1 ? 
ATOM   3485 C  CA  . HIS A 1 464 ? -1.308  -8.036  85.618  1.000 78.563  ? 464 HIS AAA CA  1 ? 
ATOM   3486 C  C   . HIS A 1 464 ? -1.304  -9.489  85.199  1.000 83.866  ? 464 HIS AAA C   1 ? 
ATOM   3487 O  O   . HIS A 1 464 ? -0.417  -10.257 85.602  1.000 83.611  ? 464 HIS AAA O   1 ? 
ATOM   3488 C  CB  . HIS A 1 464 ? -2.325  -7.793  86.731  1.000 80.267  ? 464 HIS AAA CB  1 ? 
ATOM   3489 C  CG  . HIS A 1 464 ? -2.039  -8.574  87.961  1.000 83.778  ? 464 HIS AAA CG  1 ? 
ATOM   3490 N  ND1 . HIS A 1 464 ? -1.104  -8.161  88.882  1.000 86.453  ? 464 HIS AAA ND1 1 ? 
ATOM   3491 C  CD2 . HIS A 1 464 ? -2.547  -9.737  88.419  1.000 86.181  ? 464 HIS AAA CD2 1 ? 
ATOM   3492 C  CE1 . HIS A 1 464 ? -1.053  -9.030  89.868  1.000 87.641  ? 464 HIS AAA CE1 1 ? 
ATOM   3493 N  NE2 . HIS A 1 464 ? -1.926  -10.009 89.607  1.000 88.816  ? 464 HIS AAA NE2 1 ? 
ATOM   3494 N  N   . GLU A 1 465 ? -2.329  -9.843  84.447  1.000 95.706  ? 465 GLU AAA N   1 ? 
ATOM   3495 C  CA  . GLU A 1 465 ? -2.426  -11.176 83.843  1.000 102.183 ? 465 GLU AAA CA  1 ? 
ATOM   3496 C  C   . GLU A 1 465 ? -1.053  -11.583 83.306  1.000 102.613 ? 465 GLU AAA C   1 ? 
ATOM   3497 O  O   . GLU A 1 465 ? -0.540  -12.649 83.655  1.000 100.074 ? 465 GLU AAA O   1 ? 
ATOM   3498 C  CB  . GLU A 1 465 ? -3.470  -11.203 82.728  1.000 109.107 ? 465 GLU AAA CB  1 ? 
ATOM   3499 C  CG  . GLU A 1 465 ? -3.954  -12.598 82.403  1.000 114.388 ? 465 GLU AAA CG  1 ? 
ATOM   3500 C  CD  . GLU A 1 465 ? -5.105  -12.635 81.415  1.000 124.768 ? 465 GLU AAA CD  1 ? 
ATOM   3501 O  OE1 . GLU A 1 465 ? -5.143  -11.766 80.515  1.000 129.715 ? 465 GLU AAA OE1 1 ? 
ATOM   3502 O  OE2 . GLU A 1 465 ? -5.960  -13.534 81.550  1.000 135.865 ? 465 GLU AAA OE2 1 ? 
ATOM   3503 N  N   . LYS A 1 466 ? -0.454  -10.716 82.500  1.000 108.636 ? 466 LYS AAA N   1 ? 
ATOM   3504 C  CA  . LYS A 1 466 ? 0.816   -11.024 81.812  1.000 117.910 ? 466 LYS AAA CA  1 ? 
ATOM   3505 C  C   . LYS A 1 466 ? 1.809   -11.622 82.793  1.000 121.293 ? 466 LYS AAA C   1 ? 
ATOM   3506 O  O   . LYS A 1 466 ? 2.319   -12.721 82.540  1.000 135.457 ? 466 LYS AAA O   1 ? 
ATOM   3507 C  CB  . LYS A 1 466 ? 1.383   -9.771  81.134  1.000 120.948 ? 466 LYS AAA CB  1 ? 
ATOM   3508 N  N   . THR A 1 467 ? 2.049   -10.932 83.902  1.000 114.175 ? 467 THR AAA N   1 ? 
ATOM   3509 C  CA  . THR A 1 467 ? 3.112   -11.325 84.841  1.000 107.892 ? 467 THR AAA CA  1 ? 
ATOM   3510 C  C   . THR A 1 467 ? 2.601   -11.234 86.269  1.000 103.694 ? 467 THR AAA C   1 ? 
ATOM   3511 O  O   . THR A 1 467 ? 2.825   -10.262 86.979  1.000 105.123 ? 467 THR AAA O   1 ? 
ATOM   3512 C  CB  . THR A 1 467 ? 4.381   -10.500 84.583  1.000 110.712 ? 467 THR AAA CB  1 ? 
ATOM   3513 O  OG1 . THR A 1 467 ? 4.006   -9.219  84.071  1.000 105.644 ? 467 THR AAA OG1 1 ? 
ATOM   3514 C  CG2 . THR A 1 467 ? 5.320   -11.179 83.609  1.000 113.506 ? 467 THR AAA CG2 1 ? 
ATOM   3515 N  N   . PRO A 1 468 ? 1.901   -12.283 86.714  1.000 101.678 ? 468 PRO AAA N   1 ? 
ATOM   3516 C  CA  . PRO A 1 468 ? 1.111   -12.186 87.934  1.000 104.384 ? 468 PRO AAA CA  1 ? 
ATOM   3517 C  C   . PRO A 1 468 ? 1.924   -12.239 89.233  1.000 105.759 ? 468 PRO AAA C   1 ? 
ATOM   3518 O  O   . PRO A 1 468 ? 2.782   -13.128 89.430  1.000 113.882 ? 468 PRO AAA O   1 ? 
ATOM   3519 C  CB  . PRO A 1 468 ? 0.170   -13.396 87.822  1.000 104.978 ? 468 PRO AAA CB  1 ? 
ATOM   3520 C  CG  . PRO A 1 468 ? 0.949   -14.413 87.008  1.000 105.301 ? 468 PRO AAA CG  1 ? 
ATOM   3521 C  CD  . PRO A 1 468 ? 1.826   -13.605 86.076  1.000 102.589 ? 468 PRO AAA CD  1 ? 
ATOM   3522 N  N   . VAL A 1 469 ? 1.596   -11.298 90.126  1.000 104.404 ? 469 VAL AAA N   1 ? 
ATOM   3523 C  CA  . VAL A 1 469 ? 2.310   -11.094 91.427  1.000 108.607 ? 469 VAL AAA CA  1 ? 
ATOM   3524 C  C   . VAL A 1 469 ? 1.402   -11.085 92.686  1.000 108.069 ? 469 VAL AAA C   1 ? 
ATOM   3525 O  O   . VAL A 1 469 ? 1.915   -11.394 93.788  1.000 106.832 ? 469 VAL AAA O   1 ? 
ATOM   3526 C  CB  . VAL A 1 469 ? 3.157   -9.805  91.346  1.000 113.276 ? 469 VAL AAA CB  1 ? 
ATOM   3527 C  CG1 . VAL A 1 469 ? 4.168   -9.861  90.208  1.000 112.196 ? 469 VAL AAA CG1 1 ? 
ATOM   3528 C  CG2 . VAL A 1 469 ? 2.305   -8.551  91.217  1.000 116.589 ? 469 VAL AAA CG2 1 ? 
ATOM   3529 N  N   . SER A 1 470 ? 0.097   -10.836 92.545  1.000 108.251 ? 470 SER AAA N   1 ? 
ATOM   3530 C  CA  . SER A 1 470 ? -0.759  -10.438 93.694  1.000 111.078 ? 470 SER AAA CA  1 ? 
ATOM   3531 C  C   . SER A 1 470 ? -2.097  -11.167 93.711  1.000 112.855 ? 470 SER AAA C   1 ? 
ATOM   3532 O  O   . SER A 1 470 ? -3.051  -10.728 93.065  1.000 120.068 ? 470 SER AAA O   1 ? 
ATOM   3533 C  CB  . SER A 1 470 ? -0.973  -8.943  93.697  1.000 110.240 ? 470 SER AAA CB  1 ? 
ATOM   3534 O  OG  . SER A 1 470 ? -1.816  -8.554  94.772  1.000 108.327 ? 470 SER AAA OG  1 ? 
ATOM   3535 N  N   . ASP A 1 471 ? -2.176  -12.212 94.517  1.000 113.778 ? 471 ASP AAA N   1 ? 
ATOM   3536 C  CA  . ASP A 1 471 ? -3.352  -13.114 94.518  1.000 118.272 ? 471 ASP AAA CA  1 ? 
ATOM   3537 C  C   . ASP A 1 471 ? -4.659  -12.323 94.669  1.000 107.966 ? 471 ASP AAA C   1 ? 
ATOM   3538 O  O   . ASP A 1 471 ? -5.727  -12.779 94.197  1.000 95.279  ? 471 ASP AAA O   1 ? 
ATOM   3539 C  CB  . ASP A 1 471 ? -3.222  -14.172 95.619  1.000 132.596 ? 471 ASP AAA CB  1 ? 
ATOM   3540 C  CG  . ASP A 1 471 ? -1.828  -14.770 95.748  1.000 142.620 ? 471 ASP AAA CG  1 ? 
ATOM   3541 O  OD1 . ASP A 1 471 ? -0.864  -13.984 95.899  1.000 154.143 ? 471 ASP AAA OD1 1 ? 
ATOM   3542 O  OD2 . ASP A 1 471 ? -1.714  -16.013 95.694  1.000 145.347 ? 471 ASP AAA OD2 1 ? 
ATOM   3543 N  N   . ARG A 1 472 ? -4.571  -11.145 95.281  1.000 107.955 ? 472 ARG AAA N   1 ? 
ATOM   3544 C  CA  . ARG A 1 472 ? -5.729  -10.256 95.529  1.000 118.280 ? 472 ARG AAA CA  1 ? 
ATOM   3545 C  C   . ARG A 1 472 ? -6.257  -9.668  94.229  1.000 122.410 ? 472 ARG AAA C   1 ? 
ATOM   3546 O  O   . ARG A 1 472 ? -7.480  -9.646  94.019  1.000 131.060 ? 472 ARG AAA O   1 ? 
ATOM   3547 C  CB  . ARG A 1 472 ? -5.358  -9.111  96.481  1.000 124.225 ? 472 ARG AAA CB  1 ? 
ATOM   3548 C  CG  . ARG A 1 472 ? -4.691  -9.532  97.786  1.000 129.851 ? 472 ARG AAA CG  1 ? 
ATOM   3549 C  CD  . ARG A 1 472 ? -4.427  -8.353  98.714  1.000 134.093 ? 472 ARG AAA CD  1 ? 
ATOM   3550 N  NE  . ARG A 1 472 ? -5.590  -7.948  99.503  1.000 137.861 ? 472 ARG AAA NE  1 ? 
ATOM   3551 C  CZ  . ARG A 1 472 ? -5.691  -6.822  100.218 1.000 136.537 ? 472 ARG AAA CZ  1 ? 
ATOM   3552 N  NH1 . ARG A 1 472 ? -4.697  -5.950  100.260 1.000 133.682 ? 472 ARG AAA NH1 1 ? 
ATOM   3553 N  NH2 . ARG A 1 472 ? -6.799  -6.566  100.893 1.000 139.032 ? 472 ARG AAA NH2 1 ? 
ATOM   3554 N  N   . VAL A 1 473 ? -5.346  -9.162  93.400  1.000 122.721 ? 473 VAL AAA N   1 ? 
ATOM   3555 C  CA  . VAL A 1 473 ? -5.687  -8.547  92.094  1.000 116.653 ? 473 VAL AAA CA  1 ? 
ATOM   3556 C  C   . VAL A 1 473 ? -6.307  -9.622  91.241  1.000 116.032 ? 473 VAL AAA C   1 ? 
ATOM   3557 O  O   . VAL A 1 473 ? -7.366  -9.415  90.652  1.000 120.112 ? 473 VAL AAA O   1 ? 
ATOM   3558 C  CB  . VAL A 1 473 ? -4.455  -7.961  91.372  1.000 112.507 ? 473 VAL AAA CB  1 ? 
ATOM   3559 C  CG1 . VAL A 1 473 ? -4.776  -7.555  89.939  1.000 111.801 ? 473 VAL AAA CG1 1 ? 
ATOM   3560 C  CG2 . VAL A 1 473 ? -3.842  -6.792  92.124  1.000 112.105 ? 473 VAL AAA CG2 1 ? 
ATOM   3561 N  N   . THR A 1 474 ? -5.614  -10.744 91.176  1.000 111.217 ? 474 THR AAA N   1 ? 
ATOM   3562 C  CA  . THR A 1 474 ? -6.109  -11.917 90.451  1.000 107.022 ? 474 THR AAA CA  1 ? 
ATOM   3563 C  C   . THR A 1 474 ? -7.521  -12.263 90.909  1.000 104.365 ? 474 THR AAA C   1 ? 
ATOM   3564 O  O   . THR A 1 474 ? -8.443  -12.324 90.072  1.000 101.697 ? 474 THR AAA O   1 ? 
ATOM   3565 C  CB  . THR A 1 474 ? -5.192  -13.131 90.647  1.000 104.433 ? 474 THR AAA CB  1 ? 
ATOM   3566 O  OG1 . THR A 1 474 ? -3.877  -12.762 90.235  1.000 105.542 ? 474 THR AAA OG1 1 ? 
ATOM   3567 C  CG2 . THR A 1 474 ? -5.635  -14.343 89.858  1.000 105.977 ? 474 THR AAA CG2 1 ? 
ATOM   3568 N  N   . LYS A 1 475 ? -7.682  -12.491 92.210  1.000 103.050 ? 475 LYS AAA N   1 ? 
ATOM   3569 C  CA  . LYS A 1 475 ? -9.013  -12.841 92.756  1.000 107.370 ? 475 LYS AAA CA  1 ? 
ATOM   3570 C  C   . LYS A 1 475 ? -10.060 -11.902 92.162  1.000 106.104 ? 475 LYS AAA C   1 ? 
ATOM   3571 O  O   . LYS A 1 475 ? -11.017 -12.372 91.505  1.000 115.198 ? 475 LYS AAA O   1 ? 
ATOM   3572 C  CB  . LYS A 1 475 ? -9.022  -12.765 94.287  1.000 110.707 ? 475 LYS AAA CB  1 ? 
ATOM   3573 C  CG  . LYS A 1 475 ? -10.276 -13.338 94.931  1.000 116.210 ? 475 LYS AAA CG  1 ? 
ATOM   3574 C  CD  . LYS A 1 475 ? -10.424 -13.035 96.403  1.000 121.141 ? 475 LYS AAA CD  1 ? 
ATOM   3575 C  CE  . LYS A 1 475 ? -11.826 -13.319 96.900  1.000 127.436 ? 475 LYS AAA CE  1 ? 
ATOM   3576 N  NZ  . LYS A 1 475 ? -11.957 -13.092 98.357  1.000 130.539 ? 475 LYS AAA NZ  1 ? 
ATOM   3577 N  N   . CYS A 1 476 ? -9.849  -10.605 92.362  1.000 100.584 ? 476 CYS AAA N   1 ? 
ATOM   3578 C  CA  . CYS A 1 476 ? -10.789 -9.564  91.906  1.000 98.865  ? 476 CYS AAA CA  1 ? 
ATOM   3579 C  C   . CYS A 1 476 ? -11.007 -9.604  90.403  1.000 95.231  ? 476 CYS AAA C   1 ? 
ATOM   3580 O  O   . CYS A 1 476 ? -12.139 -9.389  89.932  1.000 91.769  ? 476 CYS AAA O   1 ? 
ATOM   3581 C  CB  . CYS A 1 476 ? -10.333 -8.167  92.307  1.000 103.173 ? 476 CYS AAA CB  1 ? 
ATOM   3582 S  SG  . CYS A 1 476 ? -10.523 -7.813  94.075  1.000 114.197 ? 476 CYS AAA SG  1 ? 
ATOM   3583 N  N   . CYS A 1 477 ? -9.942  -9.871  89.664  1.000 97.989  ? 477 CYS AAA N   1 ? 
ATOM   3584 C  CA  . CYS A 1 477 ? -9.996  -9.825  88.188  1.000 104.326 ? 477 CYS AAA CA  1 ? 
ATOM   3585 C  C   . CYS A 1 477 ? -10.774 -11.013 87.648  1.000 106.389 ? 477 CYS AAA C   1 ? 
ATOM   3586 O  O   . CYS A 1 477 ? -11.737 -10.804 86.894  1.000 111.039 ? 477 CYS AAA O   1 ? 
ATOM   3587 C  CB  . CYS A 1 477 ? -8.597  -9.747  87.584  1.000 106.941 ? 477 CYS AAA CB  1 ? 
ATOM   3588 S  SG  . CYS A 1 477 ? -7.790  -8.145  87.860  1.000 107.530 ? 477 CYS AAA SG  1 ? 
ATOM   3589 N  N   . THR A 1 478 ? -10.422 -12.217 88.087  1.000 109.309 ? 478 THR AAA N   1 ? 
ATOM   3590 C  CA  . THR A 1 478 ? -11.059 -13.473 87.618  1.000 113.948 ? 478 THR AAA CA  1 ? 
ATOM   3591 C  C   . THR A 1 478 ? -12.434 -13.763 88.225  1.000 116.464 ? 478 THR AAA C   1 ? 
ATOM   3592 O  O   . THR A 1 478 ? -13.279 -14.379 87.524  1.000 111.948 ? 478 THR AAA O   1 ? 
ATOM   3593 C  CB  . THR A 1 478 ? -10.128 -14.661 87.894  1.000 113.959 ? 478 THR AAA CB  1 ? 
ATOM   3594 O  OG1 . THR A 1 478 ? -9.900  -14.735 89.302  1.000 111.059 ? 478 THR AAA OG1 1 ? 
ATOM   3595 C  CG2 . THR A 1 478 ? -8.805  -14.546 87.168  1.000 113.635 ? 478 THR AAA CG2 1 ? 
ATOM   3596 N  N   . GLU A 1 479 ? -12.678 -13.372 89.477  1.000 122.335 ? 479 GLU AAA N   1 ? 
ATOM   3597 C  CA  . GLU A 1 479 ? -13.883 -13.835 90.218  1.000 123.737 ? 479 GLU AAA CA  1 ? 
ATOM   3598 C  C   . GLU A 1 479 ? -15.205 -13.423 89.569  1.000 117.552 ? 479 GLU AAA C   1 ? 
ATOM   3599 O  O   . GLU A 1 479 ? -16.188 -14.213 89.573  1.000 118.871 ? 479 GLU AAA O   1 ? 
ATOM   3600 C  CB  . GLU A 1 479 ? -13.866 -13.323 91.661  1.000 131.143 ? 479 GLU AAA CB  1 ? 
ATOM   3601 C  CG  . GLU A 1 479 ? -14.943 -13.948 92.535  1.000 139.241 ? 479 GLU AAA CG  1 ? 
ATOM   3602 C  CD  . GLU A 1 479 ? -14.736 -13.788 94.032  1.000 148.098 ? 479 GLU AAA CD  1 ? 
ATOM   3603 O  OE1 . GLU A 1 479 ? -14.136 -12.772 94.438  1.000 162.087 ? 479 GLU AAA OE1 1 ? 
ATOM   3604 O  OE2 . GLU A 1 479 ? -15.176 -14.682 94.788  1.000 147.868 ? 479 GLU AAA OE2 1 ? 
ATOM   3605 N  N   . SER A 1 480 ? -15.286 -12.201 89.099  1.000 108.439 ? 480 SER AAA N   1 ? 
ATOM   3606 C  CA  . SER A 1 480 ? -16.537 -11.722 88.511  1.000 104.152 ? 480 SER AAA CA  1 ? 
ATOM   3607 C  C   . SER A 1 480 ? -16.234 -10.439 87.807  1.000 101.171 ? 480 SER AAA C   1 ? 
ATOM   3608 O  O   . SER A 1 480 ? -15.666 -9.539  88.425  1.000 99.924  ? 480 SER AAA O   1 ? 
ATOM   3609 C  CB  . SER A 1 480 ? -17.599 -11.537 89.560  1.000 102.993 ? 480 SER AAA CB  1 ? 
ATOM   3610 O  OG  . SER A 1 480 ? -18.525 -10.537 89.167  1.000 105.165 ? 480 SER AAA OG  1 ? 
ATOM   3611 N  N   . LEU A 1 481 ? -16.672 -10.359 86.571  1.000 99.564  ? 481 LEU AAA N   1 ? 
ATOM   3612 C  CA  . LEU A 1 481 ? -16.354 -9.222  85.714  1.000 96.323  ? 481 LEU AAA CA  1 ? 
ATOM   3613 C  C   . LEU A 1 481 ? -17.075 -8.025  86.277  1.000 94.437  ? 481 LEU AAA C   1 ? 
ATOM   3614 O  O   . LEU A 1 481 ? -16.516 -6.938  86.369  1.000 96.696  ? 481 LEU AAA O   1 ? 
ATOM   3615 C  CB  . LEU A 1 481 ? -16.810 -9.538  84.288  1.000 97.097  ? 481 LEU AAA CB  1 ? 
ATOM   3616 C  CG  . LEU A 1 481 ? -16.640 -8.414  83.271  1.000 99.682  ? 481 LEU AAA CG  1 ? 
ATOM   3617 C  CD1 . LEU A 1 481 ? -15.244 -7.816  83.342  1.000 99.814  ? 481 LEU AAA CD1 1 ? 
ATOM   3618 C  CD2 . LEU A 1 481 ? -16.934 -8.920  81.868  1.000 102.663 ? 481 LEU AAA CD2 1 ? 
ATOM   3619 N  N   . VAL A 1 482 ? -18.282 -8.281  86.722  1.000 93.102  ? 482 VAL AAA N   1 ? 
ATOM   3620 C  CA  . VAL A 1 482 ? -19.204 -7.197  87.091  1.000 93.739  ? 482 VAL AAA CA  1 ? 
ATOM   3621 C  C   . VAL A 1 482 ? -18.829 -6.564  88.431  1.000 97.423  ? 482 VAL AAA C   1 ? 
ATOM   3622 O  O   . VAL A 1 482 ? -18.985 -5.348  88.559  1.000 97.562  ? 482 VAL AAA O   1 ? 
ATOM   3623 C  CB  . VAL A 1 482 ? -20.652 -7.717  87.080  1.000 94.913  ? 482 VAL AAA CB  1 ? 
ATOM   3624 C  CG1 . VAL A 1 482 ? -21.566 -6.907  87.980  1.000 92.736  ? 482 VAL AAA CG1 1 ? 
ATOM   3625 C  CG2 . VAL A 1 482 ? -21.195 -7.775  85.662  1.000 97.419  ? 482 VAL AAA CG2 1 ? 
ATOM   3626 N  N   . ASN A 1 483 ? -18.303 -7.335  89.383  1.000 101.639 ? 483 ASN AAA N   1 ? 
ATOM   3627 C  CA  . ASN A 1 483 ? -18.052 -6.853  90.773  1.000 98.647  ? 483 ASN AAA CA  1 ? 
ATOM   3628 C  C   . ASN A 1 483 ? -16.630 -6.342  91.022  1.000 90.737  ? 483 ASN AAA C   1 ? 
ATOM   3629 O  O   . ASN A 1 483 ? -16.289 -5.997  92.173  1.000 85.794  ? 483 ASN AAA O   1 ? 
ATOM   3630 C  CB  . ASN A 1 483 ? -18.301 -7.953  91.809  1.000 104.977 ? 483 ASN AAA CB  1 ? 
ATOM   3631 C  CG  . ASN A 1 483 ? -19.698 -8.531  91.748  1.000 111.717 ? 483 ASN AAA CG  1 ? 
ATOM   3632 O  OD1 . ASN A 1 483 ? -19.899 -9.702  92.065  1.000 120.542 ? 483 ASN AAA OD1 1 ? 
ATOM   3633 N  ND2 . ASN A 1 483 ? -20.664 -7.719  91.350  1.000 112.413 ? 483 ASN AAA ND2 1 ? 
ATOM   3634 N  N   . ARG A 1 484 ? -15.815 -6.269  89.978  1.000 86.249  ? 484 ARG AAA N   1 ? 
ATOM   3635 C  CA  . ARG A 1 484 ? -14.405 -5.837  90.074  1.000 85.622  ? 484 ARG AAA CA  1 ? 
ATOM   3636 C  C   . ARG A 1 484 ? -14.249 -4.531  90.843  1.000 86.148  ? 484 ARG AAA C   1 ? 
ATOM   3637 O  O   . ARG A 1 484 ? -13.443 -4.466  91.790  1.000 87.428  ? 484 ARG AAA O   1 ? 
ATOM   3638 C  CB  . ARG A 1 484 ? -13.823 -5.648  88.673  1.000 89.445  ? 484 ARG AAA CB  1 ? 
ATOM   3639 C  CG  . ARG A 1 484 ? -13.539 -6.949  87.942  1.000 93.249  ? 484 ARG AAA CG  1 ? 
ATOM   3640 C  CD  . ARG A 1 484 ? -12.980 -6.699  86.557  1.000 95.045  ? 484 ARG AAA CD  1 ? 
ATOM   3641 N  NE  . ARG A 1 484 ? -12.423 -7.908  85.973  1.000 96.068  ? 484 ARG AAA NE  1 ? 
ATOM   3642 C  CZ  . ARG A 1 484 ? -11.788 -7.963  84.807  1.000 100.253 ? 484 ARG AAA CZ  1 ? 
ATOM   3643 N  NH1 . ARG A 1 484 ? -11.624 -6.868  84.081  1.000 99.782  ? 484 ARG AAA NH1 1 ? 
ATOM   3644 N  NH2 . ARG A 1 484 ? -11.316 -9.117  84.371  1.000 106.462 ? 484 ARG AAA NH2 1 ? 
ATOM   3645 N  N   . ARG A 1 485 ? -14.972 -3.496  90.443  1.000 89.902  ? 485 ARG AAA N   1 ? 
ATOM   3646 C  CA  . ARG A 1 485 ? -14.817 -2.168  91.070  1.000 95.204  ? 485 ARG AAA CA  1 ? 
ATOM   3647 C  C   . ARG A 1 485 ? -15.067 -2.287  92.575  1.000 95.947  ? 485 ARG AAA C   1 ? 
ATOM   3648 O  O   . ARG A 1 485 ? -14.244 -1.840  93.370  1.000 96.353  ? 485 ARG AAA O   1 ? 
ATOM   3649 C  CB  . ARG A 1 485 ? -15.694 -1.146  90.332  1.000 98.404  ? 485 ARG AAA CB  1 ? 
ATOM   3650 C  CG  . ARG A 1 485 ? -15.325 0.310   90.582  1.000 102.403 ? 485 ARG AAA CG  1 ? 
ATOM   3651 C  CD  . ARG A 1 485 ? -15.840 0.820   91.915  1.000 106.824 ? 485 ARG AAA CD  1 ? 
ATOM   3652 N  NE  . ARG A 1 485 ? -17.292 0.738   92.025  1.000 107.352 ? 485 ARG AAA NE  1 ? 
ATOM   3653 C  CZ  . ARG A 1 485 ? -17.972 0.337   93.101  1.000 106.049 ? 485 ARG AAA CZ  1 ? 
ATOM   3654 N  NH1 . ARG A 1 485 ? -17.348 -0.058  94.201  1.000 104.445 ? 485 ARG AAA NH1 1 ? 
ATOM   3655 N  NH2 . ARG A 1 485 ? -19.292 0.320   93.060  1.000 105.517 ? 485 ARG AAA NH2 1 ? 
ATOM   3656 N  N   . PRO A 1 486 ? -16.207 -2.873  93.006  1.000 99.325  ? 486 PRO AAA N   1 ? 
ATOM   3657 C  CA  . PRO A 1 486 ? -16.437 -3.110  94.430  1.000 100.693 ? 486 PRO AAA CA  1 ? 
ATOM   3658 C  C   . PRO A 1 486 ? -15.378 -3.970  95.102  1.000 103.348 ? 486 PRO AAA C   1 ? 
ATOM   3659 O  O   . PRO A 1 486 ? -15.047 -3.723  96.257  1.000 101.931 ? 486 PRO AAA O   1 ? 
ATOM   3660 C  CB  . PRO A 1 486 ? -17.768 -3.874  94.465  1.000 103.361 ? 486 PRO AAA CB  1 ? 
ATOM   3661 C  CG  . PRO A 1 486 ? -18.488 -3.427  93.216  1.000 105.155 ? 486 PRO AAA CG  1 ? 
ATOM   3662 C  CD  . PRO A 1 486 ? -17.403 -3.151  92.196  1.000 104.014 ? 486 PRO AAA CD  1 ? 
ATOM   3663 N  N   . CYS A 1 487 ? -14.881 -4.954  94.358  1.000 107.756 ? 487 CYS AAA N   1 ? 
ATOM   3664 C  CA  . CYS A 1 487 ? -13.844 -5.878  94.857  1.000 110.472 ? 487 CYS AAA CA  1 ? 
ATOM   3665 C  C   . CYS A 1 487 ? -12.571 -5.123  95.161  1.000 107.080 ? 487 CYS AAA C   1 ? 
ATOM   3666 O  O   . CYS A 1 487 ? -11.873 -5.459  96.124  1.000 108.511 ? 487 CYS AAA O   1 ? 
ATOM   3667 C  CB  . CYS A 1 487 ? -13.504 -6.976  93.852  1.000 116.940 ? 487 CYS AAA CB  1 ? 
ATOM   3668 S  SG  . CYS A 1 487 ? -12.461 -8.293  94.540  1.000 125.969 ? 487 CYS AAA SG  1 ? 
ATOM   3669 N  N   . PHE A 1 488 ? -12.264 -4.155  94.311  1.000 102.694 ? 488 PHE AAA N   1 ? 
ATOM   3670 C  CA  . PHE A 1 488 ? -11.010 -3.406  94.437  1.000 99.027  ? 488 PHE AAA CA  1 ? 
ATOM   3671 C  C   . PHE A 1 488 ? -11.207 -2.362  95.508  1.000 99.855  ? 488 PHE AAA C   1 ? 
ATOM   3672 O  O   . PHE A 1 488 ? -10.435 -2.286  96.475  1.000 103.440 ? 488 PHE AAA O   1 ? 
ATOM   3673 C  CB  . PHE A 1 488 ? -10.564 -2.831  93.090  1.000 94.765  ? 488 PHE AAA CB  1 ? 
ATOM   3674 C  CG  . PHE A 1 488 ? -9.702  -3.774  92.291  1.000 91.183  ? 488 PHE AAA CG  1 ? 
ATOM   3675 C  CD1 . PHE A 1 488 ? -8.332  -3.822  92.495  1.000 89.923  ? 488 PHE AAA CD1 1 ? 
ATOM   3676 C  CD2 . PHE A 1 488 ? -10.259 -4.639  91.361  1.000 90.173  ? 488 PHE AAA CD2 1 ? 
ATOM   3677 C  CE1 . PHE A 1 488 ? -7.539  -4.699  91.771  1.000 90.031  ? 488 PHE AAA CE1 1 ? 
ATOM   3678 C  CE2 . PHE A 1 488 ? -9.464  -5.515  90.638  1.000 89.268  ? 488 PHE AAA CE2 1 ? 
ATOM   3679 C  CZ  . PHE A 1 488 ? -8.106  -5.547  90.847  1.000 88.676  ? 488 PHE AAA CZ  1 ? 
ATOM   3680 N  N   . SER A 1 489 ? -12.280 -1.616  95.349  1.000 103.199 ? 489 SER AAA N   1 ? 
ATOM   3681 C  CA  . SER A 1 489 ? -12.653 -0.563  96.292  1.000 109.446 ? 489 SER AAA CA  1 ? 
ATOM   3682 C  C   . SER A 1 489 ? -12.597 -1.154  97.692  1.000 104.441 ? 489 SER AAA C   1 ? 
ATOM   3683 O  O   . SER A 1 489 ? -11.943 -0.558  98.561  1.000 99.280  ? 489 SER AAA O   1 ? 
ATOM   3684 C  CB  . SER A 1 489 ? -14.017 -0.013  95.984  1.000 119.951 ? 489 SER AAA CB  1 ? 
ATOM   3685 O  OG  . SER A 1 489 ? -14.056 0.505   94.665  1.000 131.469 ? 489 SER AAA OG  1 ? 
ATOM   3686 N  N   . ALA A 1 490 ? -13.200 -2.335  97.867  1.000 104.657 ? 490 ALA AAA N   1 ? 
ATOM   3687 C  CA  . ALA A 1 490 ? -13.221 -3.062  99.161  1.000 110.673 ? 490 ALA AAA CA  1 ? 
ATOM   3688 C  C   . ALA A 1 490 ? -11.849 -3.155  99.834  1.000 113.813 ? 490 ALA AAA C   1 ? 
ATOM   3689 O  O   . ALA A 1 490 ? -11.742 -3.028  101.086 1.000 116.220 ? 490 ALA AAA O   1 ? 
ATOM   3690 C  CB  . ALA A 1 490 ? -13.787 -4.443  98.939  1.000 112.121 ? 490 ALA AAA CB  1 ? 
ATOM   3691 N  N   . LEU A 1 491 ? -10.818 -3.380  99.031  1.000 120.049 ? 491 LEU AAA N   1 ? 
ATOM   3692 C  CA  . LEU A 1 491 ? -9.537  -3.896  99.550  1.000 125.283 ? 491 LEU AAA CA  1 ? 
ATOM   3693 C  C   . LEU A 1 491 ? -8.959  -2.914  100.557 1.000 131.939 ? 491 LEU AAA C   1 ? 
ATOM   3694 O  O   . LEU A 1 491 ? -8.918  -1.707  100.295 1.000 134.569 ? 491 LEU AAA O   1 ? 
ATOM   3695 C  CB  . LEU A 1 491 ? -8.564  -4.146  98.391  1.000 123.332 ? 491 LEU AAA CB  1 ? 
ATOM   3696 C  CG  . LEU A 1 491 ? -8.986  -5.211  97.377  1.000 120.400 ? 491 LEU AAA CG  1 ? 
ATOM   3697 C  CD1 . LEU A 1 491 ? -8.132  -5.138  96.122  1.000 118.760 ? 491 LEU AAA CD1 1 ? 
ATOM   3698 C  CD2 . LEU A 1 491 ? -8.923  -6.607  97.975  1.000 118.445 ? 491 LEU AAA CD2 1 ? 
ATOM   3699 N  N   . GLU A 1 492 ? -8.541  -3.448  101.689 1.000 137.478 ? 492 GLU AAA N   1 ? 
ATOM   3700 C  CA  . GLU A 1 492 ? -7.822  -2.669  102.702 1.000 138.134 ? 492 GLU AAA CA  1 ? 
ATOM   3701 C  C   . GLU A 1 492 ? -6.344  -2.782  102.389 1.000 134.465 ? 492 GLU AAA C   1 ? 
ATOM   3702 O  O   . GLU A 1 492 ? -5.960  -3.606  101.546 1.000 130.648 ? 492 GLU AAA O   1 ? 
ATOM   3703 C  CB  . GLU A 1 492 ? -8.173  -3.186  104.098 1.000 143.315 ? 492 GLU AAA CB  1 ? 
ATOM   3704 C  CG  . GLU A 1 492 ? -9.646  -3.029  104.437 1.000 143.045 ? 492 GLU AAA CG  1 ? 
ATOM   3705 C  CD  . GLU A 1 492 ? -10.003 -1.727  105.131 1.000 140.926 ? 492 GLU AAA CD  1 ? 
ATOM   3706 O  OE1 . GLU A 1 492 ? -9.576  -0.666  104.640 1.000 140.183 ? 492 GLU AAA OE1 1 ? 
ATOM   3707 O  OE2 . GLU A 1 492 ? -10.705 -1.776  106.158 1.000 139.110 ? 492 GLU AAA OE2 1 ? 
ATOM   3708 N  N   . VAL A 1 493 ? -5.524  -2.004  103.071 1.000 129.770 ? 493 VAL AAA N   1 ? 
ATOM   3709 C  CA  . VAL A 1 493 ? -4.060  -2.011  102.803 1.000 127.137 ? 493 VAL AAA CA  1 ? 
ATOM   3710 C  C   . VAL A 1 493 ? -3.508  -3.404  103.063 1.000 126.270 ? 493 VAL AAA C   1 ? 
ATOM   3711 O  O   . VAL A 1 493 ? -3.964  -4.069  104.002 1.000 129.235 ? 493 VAL AAA O   1 ? 
ATOM   3712 C  CB  . VAL A 1 493 ? -3.297  -0.966  103.643 1.000 126.296 ? 493 VAL AAA CB  1 ? 
ATOM   3713 C  CG1 . VAL A 1 493 ? -3.854  0.434   103.444 1.000 130.759 ? 493 VAL AAA CG1 1 ? 
ATOM   3714 C  CG2 . VAL A 1 493 ? -3.252  -1.324  105.123 1.000 122.865 ? 493 VAL AAA CG2 1 ? 
ATOM   3715 N  N   . ASP A 1 494 ? -2.511  -3.821  102.291 1.000 127.413 ? 494 ASP AAA N   1 ? 
ATOM   3716 C  CA  . ASP A 1 494 ? -1.981  -5.194  102.450 1.000 132.044 ? 494 ASP AAA CA  1 ? 
ATOM   3717 C  C   . ASP A 1 494 ? -1.013  -5.215  103.631 1.000 133.328 ? 494 ASP AAA C   1 ? 
ATOM   3718 O  O   . ASP A 1 494 ? 0.053   -4.593  103.544 1.000 126.529 ? 494 ASP AAA O   1 ? 
ATOM   3719 C  CB  . ASP A 1 494 ? -1.313  -5.668  101.154 1.000 134.027 ? 494 ASP AAA CB  1 ? 
ATOM   3720 C  CG  . ASP A 1 494 ? -1.210  -7.178  101.016 1.000 133.572 ? 494 ASP AAA CG  1 ? 
ATOM   3721 O  OD1 . ASP A 1 494 ? -1.046  -7.855  102.049 1.000 138.211 ? 494 ASP AAA OD1 1 ? 
ATOM   3722 O  OD2 . ASP A 1 494 ? -1.298  -7.666  99.873  1.000 130.428 ? 494 ASP AAA OD2 1 ? 
ATOM   3723 N  N   . GLU A 1 495 ? -1.358  -5.956  104.684 1.000 140.872 ? 495 GLU AAA N   1 ? 
ATOM   3724 C  CA  . GLU A 1 495 ? -0.510  -6.100  105.896 1.000 150.705 ? 495 GLU AAA CA  1 ? 
ATOM   3725 C  C   . GLU A 1 495 ? 0.636   -7.080  105.651 1.000 161.429 ? 495 GLU AAA C   1 ? 
ATOM   3726 O  O   . GLU A 1 495 ? 1.763   -6.858  106.161 1.000 169.957 ? 495 GLU AAA O   1 ? 
ATOM   3727 C  CB  . GLU A 1 495 ? -1.368  -6.554  107.079 1.000 150.087 ? 495 GLU AAA CB  1 ? 
ATOM   3728 N  N   . THR A 1 496 ? 0.374   -8.134  104.889 1.000 165.132 ? 496 THR AAA N   1 ? 
ATOM   3729 C  CA  . THR A 1 496 ? 1.385   -9.178  104.617 1.000 163.320 ? 496 THR AAA CA  1 ? 
ATOM   3730 C  C   . THR A 1 496 ? 2.636   -8.558  104.002 1.000 168.051 ? 496 THR AAA C   1 ? 
ATOM   3731 O  O   . THR A 1 496 ? 3.756   -9.038  104.284 1.000 173.131 ? 496 THR AAA O   1 ? 
ATOM   3732 C  CB  . THR A 1 496 ? 0.858   -10.291 103.699 1.000 159.026 ? 496 THR AAA CB  1 ? 
ATOM   3733 O  OG1 . THR A 1 496 ? 0.646   -9.740  102.399 1.000 156.384 ? 496 THR AAA OG1 1 ? 
ATOM   3734 C  CG2 . THR A 1 496 ? -0.414  -10.939 104.205 1.000 158.682 ? 496 THR AAA CG2 1 ? 
ATOM   3735 N  N   . TYR A 1 497 ? 2.459   -7.515  103.199 1.000 170.587 ? 497 TYR AAA N   1 ? 
ATOM   3736 C  CA  . TYR A 1 497 ? 3.567   -6.938  102.405 1.000 170.157 ? 497 TYR AAA CA  1 ? 
ATOM   3737 C  C   . TYR A 1 497 ? 4.756   -6.488  103.252 1.000 172.599 ? 497 TYR AAA C   1 ? 
ATOM   3738 O  O   . TYR A 1 497 ? 4.627   -5.737  104.242 1.000 183.194 ? 497 TYR AAA O   1 ? 
ATOM   3739 C  CB  . TYR A 1 497 ? 3.083   -5.783  101.523 1.000 167.820 ? 497 TYR AAA CB  1 ? 
ATOM   3740 C  CG  . TYR A 1 497 ? 4.170   -5.171  100.673 1.000 162.742 ? 497 TYR AAA CG  1 ? 
ATOM   3741 C  CD1 . TYR A 1 497 ? 4.775   -5.892  99.655  1.000 154.382 ? 497 TYR AAA CD1 1 ? 
ATOM   3742 C  CD2 . TYR A 1 497 ? 4.611   -3.875  100.897 1.000 161.255 ? 497 TYR AAA CD2 1 ? 
ATOM   3743 C  CE1 . TYR A 1 497 ? 5.780   -5.340  98.875  1.000 148.981 ? 497 TYR AAA CE1 1 ? 
ATOM   3744 C  CE2 . TYR A 1 497 ? 5.614   -3.308  100.126 1.000 154.200 ? 497 TYR AAA CE2 1 ? 
ATOM   3745 C  CZ  . TYR A 1 497 ? 6.201   -4.044  99.111  1.000 150.055 ? 497 TYR AAA CZ  1 ? 
ATOM   3746 O  OH  . TYR A 1 497 ? 7.189   -3.502  98.342  1.000 148.941 ? 497 TYR AAA OH  1 ? 
ATOM   3747 N  N   . VAL A 1 498 ? 5.917   -6.937  102.799 1.000 165.572 ? 498 VAL AAA N   1 ? 
ATOM   3748 C  CA  . VAL A 1 498 ? 7.213   -6.676  103.455 1.000 165.898 ? 498 VAL AAA CA  1 ? 
ATOM   3749 C  C   . VAL A 1 498 ? 7.859   -5.483  102.753 1.000 172.705 ? 498 VAL AAA C   1 ? 
ATOM   3750 O  O   . VAL A 1 498 ? 8.259   -5.599  101.595 1.000 172.605 ? 498 VAL AAA O   1 ? 
ATOM   3751 C  CB  . VAL A 1 498 ? 8.117   -7.923  103.419 1.000 164.237 ? 498 VAL AAA CB  1 ? 
ATOM   3752 C  CG1 . VAL A 1 498 ? 9.430   -7.695  104.153 1.000 163.139 ? 498 VAL AAA CG1 1 ? 
ATOM   3753 C  CG2 . VAL A 1 498 ? 7.401   -9.145  103.974 1.000 164.013 ? 498 VAL AAA CG2 1 ? 
ATOM   3754 N  N   . PRO A 1 499 ? 7.968   -4.325  103.450 1.000 183.732 ? 499 PRO AAA N   1 ? 
ATOM   3755 C  CA  . PRO A 1 499 ? 8.453   -3.060  102.880 1.000 190.453 ? 499 PRO AAA CA  1 ? 
ATOM   3756 C  C   . PRO A 1 499 ? 9.671   -3.184  101.973 1.000 194.905 ? 499 PRO AAA C   1 ? 
ATOM   3757 O  O   . PRO A 1 499 ? 10.574  -3.954  102.261 1.000 194.282 ? 499 PRO AAA O   1 ? 
ATOM   3758 C  CB  . PRO A 1 499 ? 8.816   -2.242  104.129 1.000 190.264 ? 499 PRO AAA CB  1 ? 
ATOM   3759 C  CG  . PRO A 1 499 ? 7.834   -2.707  105.175 1.000 186.375 ? 499 PRO AAA CG  1 ? 
ATOM   3760 C  CD  . PRO A 1 499 ? 7.623   -4.177  104.876 1.000 184.975 ? 499 PRO AAA CD  1 ? 
ATOM   3761 N  N   . LYS A 1 500 ? 9.682   -2.400  100.906 1.000 193.869 ? 500 LYS AAA N   1 ? 
ATOM   3762 C  CA  . LYS A 1 500 ? 10.764  -2.490  99.917  1.000 187.120 ? 500 LYS AAA CA  1 ? 
ATOM   3763 C  C   . LYS A 1 500 ? 12.018  -1.853  100.502 1.000 173.639 ? 500 LYS AAA C   1 ? 
ATOM   3764 O  O   . LYS A 1 500 ? 11.925  -0.756  101.061 1.000 165.118 ? 500 LYS AAA O   1 ? 
ATOM   3765 C  CB  . LYS A 1 500 ? 10.359  -1.831  98.595  1.000 194.564 ? 500 LYS AAA CB  1 ? 
ATOM   3766 C  CG  . LYS A 1 500 ? 11.009  -2.448  97.364  1.000 201.246 ? 500 LYS AAA CG  1 ? 
ATOM   3767 C  CD  . LYS A 1 500 ? 10.611  -1.789  96.064  1.000 208.053 ? 500 LYS AAA CD  1 ? 
ATOM   3768 C  CE  . LYS A 1 500 ? 11.545  -2.137  94.925  1.000 211.568 ? 500 LYS AAA CE  1 ? 
ATOM   3769 N  NZ  . LYS A 1 500 ? 11.281  -1.307  93.726  1.000 213.880 ? 500 LYS AAA NZ  1 ? 
ATOM   3770 N  N   . GLU A 1 501 ? 13.145  -2.544  100.380 1.000 161.969 ? 501 GLU AAA N   1 ? 
ATOM   3771 C  CA  . GLU A 1 501 ? 14.441  -2.060  100.898 1.000 152.147 ? 501 GLU AAA CA  1 ? 
ATOM   3772 C  C   . GLU A 1 501 ? 14.696  -0.618  100.437 1.000 146.741 ? 501 GLU AAA C   1 ? 
ATOM   3773 O  O   . GLU A 1 501 ? 15.068  -0.445  99.259  1.000 137.785 ? 501 GLU AAA O   1 ? 
ATOM   3774 N  N   . ILE A 1 513 ? 16.233  15.206  82.530  1.000 177.624 ? 513 ILE AAA N   1 ? 
ATOM   3775 C  CA  . ILE A 1 513 ? 15.228  15.157  83.646  1.000 177.518 ? 513 ILE AAA CA  1 ? 
ATOM   3776 C  C   . ILE A 1 513 ? 14.627  16.540  83.921  1.000 178.083 ? 513 ILE AAA C   1 ? 
ATOM   3777 O  O   . ILE A 1 513 ? 13.400  16.632  84.169  1.000 180.049 ? 513 ILE AAA O   1 ? 
ATOM   3778 C  CB  . ILE A 1 513 ? 15.816  14.531  84.935  1.000 173.293 ? 513 ILE AAA CB  1 ? 
ATOM   3779 C  CG1 . ILE A 1 513 ? 14.895  14.779  86.136  1.000 164.323 ? 513 ILE AAA CG1 1 ? 
ATOM   3780 C  CG2 . ILE A 1 513 ? 17.239  15.010  85.209  1.000 171.559 ? 513 ILE AAA CG2 1 ? 
ATOM   3781 C  CD1 . ILE A 1 513 ? 15.218  13.951  87.355  1.000 163.832 ? 513 ILE AAA CD1 1 ? 
ATOM   3782 N  N   . CYS A 1 514 ? 15.456  17.576  83.947  1.000 174.241 ? 514 CYS AAA N   1 ? 
ATOM   3783 C  CA  . CYS A 1 514 ? 15.022  18.937  84.305  1.000 168.161 ? 514 CYS AAA CA  1 ? 
ATOM   3784 C  C   . CYS A 1 514 ? 14.380  19.588  83.103  1.000 159.218 ? 514 CYS AAA C   1 ? 
ATOM   3785 O  O   . CYS A 1 514 ? 13.645  20.563  83.274  1.000 149.398 ? 514 CYS AAA O   1 ? 
ATOM   3786 C  CB  . CYS A 1 514 ? 16.194  19.769  84.810  1.000 169.034 ? 514 CYS AAA CB  1 ? 
ATOM   3787 S  SG  . CYS A 1 514 ? 16.902  19.122  86.346  1.000 171.726 ? 514 CYS AAA SG  1 ? 
ATOM   3788 N  N   . THR A 1 515 ? 14.704  19.067  81.934  1.000 160.085 ? 515 THR AAA N   1 ? 
ATOM   3789 C  CA  . THR A 1 515 ? 14.199  19.587  80.658  1.000 166.566 ? 515 THR AAA CA  1 ? 
ATOM   3790 C  C   . THR A 1 515 ? 13.035  18.717  80.190  1.000 165.725 ? 515 THR AAA C   1 ? 
ATOM   3791 O  O   . THR A 1 515 ? 13.035  18.266  79.023  1.000 175.012 ? 515 THR AAA O   1 ? 
ATOM   3792 C  CB  . THR A 1 515 ? 15.339  19.669  79.634  1.000 171.834 ? 515 THR AAA CB  1 ? 
ATOM   3793 O  OG1 . THR A 1 515 ? 16.530  20.038  80.330  1.000 170.264 ? 515 THR AAA OG1 1 ? 
ATOM   3794 C  CG2 . THR A 1 515 ? 15.059  20.657  78.522  1.000 172.892 ? 515 THR AAA CG2 1 ? 
ATOM   3795 N  N   . LEU A 1 516 ? 12.073  18.510  81.082  1.000 158.187 ? 516 LEU AAA N   1 ? 
ATOM   3796 C  CA  . LEU A 1 516 ? 10.918  17.630  80.826  1.000 154.351 ? 516 LEU AAA CA  1 ? 
ATOM   3797 C  C   . LEU A 1 516 ? 9.651   18.459  80.792  1.000 141.792 ? 516 LEU AAA C   1 ? 
ATOM   3798 O  O   . LEU A 1 516 ? 9.543   19.461  81.513  1.000 132.342 ? 516 LEU AAA O   1 ? 
ATOM   3799 C  CB  . LEU A 1 516 ? 10.815  16.582  81.941  1.000 170.294 ? 516 LEU AAA CB  1 ? 
ATOM   3800 C  CG  . LEU A 1 516 ? 11.737  15.366  81.845  1.000 180.486 ? 516 LEU AAA CG  1 ? 
ATOM   3801 C  CD1 . LEU A 1 516 ? 11.469  14.416  83.005  1.000 190.972 ? 516 LEU AAA CD1 1 ? 
ATOM   3802 C  CD2 . LEU A 1 516 ? 11.577  14.634  80.520  1.000 178.153 ? 516 LEU AAA CD2 1 ? 
ATOM   3803 N  N   . SER A 1 517 ? 8.694   17.980  80.024  1.000 137.479 ? 517 SER AAA N   1 ? 
ATOM   3804 C  CA  . SER A 1 517 ? 7.347   18.566  79.993  1.000 138.193 ? 517 SER AAA CA  1 ? 
ATOM   3805 C  C   . SER A 1 517 ? 6.642   18.306  81.321  1.000 143.179 ? 517 SER AAA C   1 ? 
ATOM   3806 O  O   . SER A 1 517 ? 7.064   17.449  82.106  1.000 155.585 ? 517 SER AAA O   1 ? 
ATOM   3807 C  CB  . SER A 1 517 ? 6.545   18.043  78.829  1.000 132.522 ? 517 SER AAA CB  1 ? 
ATOM   3808 O  OG  . SER A 1 517 ? 6.704   16.641  78.696  1.000 130.176 ? 517 SER AAA OG  1 ? 
ATOM   3809 N  N   . GLU A 1 518 ? 5.563   19.041  81.556  1.000 138.370 ? 518 GLU AAA N   1 ? 
ATOM   3810 C  CA  . GLU A 1 518 ? 4.841   18.957  82.846  1.000 134.696 ? 518 GLU AAA CA  1 ? 
ATOM   3811 C  C   . GLU A 1 518 ? 4.357   17.526  83.053  1.000 123.420 ? 518 GLU AAA C   1 ? 
ATOM   3812 O  O   . GLU A 1 518 ? 4.624   16.914  84.116  1.000 121.877 ? 518 GLU AAA O   1 ? 
ATOM   3813 C  CB  . GLU A 1 518 ? 3.683   19.956  82.874  1.000 146.090 ? 518 GLU AAA CB  1 ? 
ATOM   3814 C  CG  . GLU A 1 518 ? 3.252   20.327  84.278  1.000 156.067 ? 518 GLU AAA CG  1 ? 
ATOM   3815 C  CD  . GLU A 1 518 ? 4.392   20.733  85.197  1.000 164.653 ? 518 GLU AAA CD  1 ? 
ATOM   3816 O  OE1 . GLU A 1 518 ? 5.241   21.551  84.775  1.000 176.088 ? 518 GLU AAA OE1 1 ? 
ATOM   3817 O  OE2 . GLU A 1 518 ? 4.439   20.215  86.325  1.000 166.766 ? 518 GLU AAA OE2 1 ? 
ATOM   3818 N  N   . LYS A 1 519 ? 3.689   17.002  82.032  1.000 114.886 ? 519 LYS AAA N   1 ? 
ATOM   3819 C  CA  . LYS A 1 519 ? 3.196   15.614  82.038  1.000 108.932 ? 519 LYS AAA CA  1 ? 
ATOM   3820 C  C   . LYS A 1 519 ? 4.358   14.660  82.264  1.000 105.210 ? 519 LYS AAA C   1 ? 
ATOM   3821 O  O   . LYS A 1 519 ? 4.186   13.662  82.962  1.000 107.331 ? 519 LYS AAA O   1 ? 
ATOM   3822 C  CB  . LYS A 1 519 ? 2.450   15.279  80.743  1.000 106.229 ? 519 LYS AAA CB  1 ? 
ATOM   3823 N  N   . GLU A 1 520 ? 5.522   14.961  81.712  1.000 101.199 ? 520 GLU AAA N   1 ? 
ATOM   3824 C  CA  . GLU A 1 520 ? 6.702   14.132  81.995  1.000 101.967 ? 520 GLU AAA CA  1 ? 
ATOM   3825 C  C   . GLU A 1 520 ? 7.071   14.204  83.476  1.000 96.421  ? 520 GLU AAA C   1 ? 
ATOM   3826 O  O   . GLU A 1 520 ? 7.008   13.183  84.158  1.000 91.195  ? 520 GLU AAA O   1 ? 
ATOM   3827 C  CB  . GLU A 1 520 ? 7.877   14.531  81.103  1.000 111.066 ? 520 GLU AAA CB  1 ? 
ATOM   3828 C  CG  . GLU A 1 520 ? 7.805   13.921  79.716  1.000 120.784 ? 520 GLU AAA CG  1 ? 
ATOM   3829 C  CD  . GLU A 1 520 ? 7.835   12.402  79.686  1.000 130.382 ? 520 GLU AAA CD  1 ? 
ATOM   3830 O  OE1 . GLU A 1 520 ? 8.522   11.807  80.544  1.000 137.954 ? 520 GLU AAA OE1 1 ? 
ATOM   3831 O  OE2 . GLU A 1 520 ? 7.165   11.818  78.810  1.000 137.384 ? 520 GLU AAA OE2 1 ? 
ATOM   3832 N  N   . ARG A 1 521 ? 7.433   15.385  83.957  1.000 98.905  ? 521 ARG AAA N   1 ? 
ATOM   3833 C  CA  . ARG A 1 521 ? 7.798   15.609  85.380  1.000 105.528 ? 521 ARG AAA CA  1 ? 
ATOM   3834 C  C   . ARG A 1 521 ? 6.812   14.858  86.282  1.000 102.489 ? 521 ARG AAA C   1 ? 
ATOM   3835 O  O   . ARG A 1 521 ? 7.219   14.142  87.253  1.000 95.357  ? 521 ARG AAA O   1 ? 
ATOM   3836 C  CB  . ARG A 1 521 ? 7.786   17.111  85.683  1.000 115.116 ? 521 ARG AAA CB  1 ? 
ATOM   3837 C  CG  . ARG A 1 521 ? 7.780   17.460  87.166  1.000 124.124 ? 521 ARG AAA CG  1 ? 
ATOM   3838 C  CD  . ARG A 1 521 ? 7.445   18.918  87.415  1.000 128.315 ? 521 ARG AAA CD  1 ? 
ATOM   3839 N  NE  . ARG A 1 521 ? 6.751   19.119  88.683  1.000 128.501 ? 521 ARG AAA NE  1 ? 
ATOM   3840 C  CZ  . ARG A 1 521 ? 5.463   18.858  88.906  1.000 127.528 ? 521 ARG AAA CZ  1 ? 
ATOM   3841 N  NH1 . ARG A 1 521 ? 4.692   18.365  87.949  1.000 128.337 ? 521 ARG AAA NH1 1 ? 
ATOM   3842 N  NH2 . ARG A 1 521 ? 4.948   19.097  90.098  1.000 125.035 ? 521 ARG AAA NH2 1 ? 
ATOM   3843 N  N   . GLN A 1 522 ? 5.532   15.003  85.959  1.000 103.722 ? 522 GLN AAA N   1 ? 
ATOM   3844 C  CA  . GLN A 1 522 ? 4.480   14.351  86.762  1.000 103.113 ? 522 GLN AAA CA  1 ? 
ATOM   3845 C  C   . GLN A 1 522 ? 4.760   12.861  86.906  1.000 99.274  ? 522 GLN AAA C   1 ? 
ATOM   3846 O  O   . GLN A 1 522 ? 4.828   12.335  88.016  1.000 99.070  ? 522 GLN AAA O   1 ? 
ATOM   3847 C  CB  . GLN A 1 522 ? 3.102   14.632  86.154  1.000 109.219 ? 522 GLN AAA CB  1 ? 
ATOM   3848 C  CG  . GLN A 1 522 ? 2.590   16.041  86.436  1.000 113.243 ? 522 GLN AAA CG  1 ? 
ATOM   3849 C  CD  . GLN A 1 522 ? 1.244   16.331  85.812  1.000 116.158 ? 522 GLN AAA CD  1 ? 
ATOM   3850 O  OE1 . GLN A 1 522 ? 0.782   15.631  84.912  1.000 119.091 ? 522 GLN AAA OE1 1 ? 
ATOM   3851 N  NE2 . GLN A 1 522 ? 0.601   17.383  86.291  1.000 115.840 ? 522 GLN AAA NE2 1 ? 
ATOM   3852 N  N   . ILE A 1 523 ? 4.959   12.199  85.785  1.000 95.475  ? 523 ILE AAA N   1 ? 
ATOM   3853 C  CA  . ILE A 1 523 ? 5.148   10.727  85.765  1.000 91.578  ? 523 ILE AAA CA  1 ? 
ATOM   3854 C  C   . ILE A 1 523 ? 6.396   10.288  86.539  1.000 92.534  ? 523 ILE AAA C   1 ? 
ATOM   3855 O  O   . ILE A 1 523 ? 6.409   9.188   87.101  1.000 87.546  ? 523 ILE AAA O   1 ? 
ATOM   3856 C  CB  . ILE A 1 523 ? 5.133   10.219  84.312  1.000 89.216  ? 523 ILE AAA CB  1 ? 
ATOM   3857 C  CG1 . ILE A 1 523 ? 3.721   10.351  83.732  1.000 93.148  ? 523 ILE AAA CG1 1 ? 
ATOM   3858 C  CG2 . ILE A 1 523 ? 5.653   8.794   84.224  1.000 88.837  ? 523 ILE AAA CG2 1 ? 
ATOM   3859 C  CD1 . ILE A 1 523 ? 3.626   10.139  82.242  1.000 97.054  ? 523 ILE AAA CD1 1 ? 
ATOM   3860 N  N   . LYS A 1 524 ? 7.428   11.111  86.596  1.000 99.681  ? 524 LYS AAA N   1 ? 
ATOM   3861 C  CA  . LYS A 1 524 ? 8.581   10.773  87.440  1.000 105.398 ? 524 LYS AAA CA  1 ? 
ATOM   3862 C  C   . LYS A 1 524 ? 8.114   10.946  88.861  1.000 101.706 ? 524 LYS AAA C   1 ? 
ATOM   3863 O  O   . LYS A 1 524 ? 8.062   9.968   89.613  1.000 96.830  ? 524 LYS AAA O   1 ? 
ATOM   3864 C  CB  . LYS A 1 524 ? 9.780   11.678  87.145  1.000 116.821 ? 524 LYS AAA CB  1 ? 
ATOM   3865 C  CG  . LYS A 1 524 ? 10.270  11.652  85.705  1.000 130.466 ? 524 LYS AAA CG  1 ? 
ATOM   3866 C  CD  . LYS A 1 524 ? 10.684  10.273  85.226  1.000 143.061 ? 524 LYS AAA CD  1 ? 
ATOM   3867 C  CE  . LYS A 1 524 ? 10.933  10.208  83.733  1.000 151.570 ? 524 LYS AAA CE  1 ? 
ATOM   3868 N  NZ  . LYS A 1 524 ? 9.675   10.306  82.954  1.000 158.793 ? 524 LYS AAA NZ  1 ? 
ATOM   3869 N  N   . LYS A 1 525 ? 7.748   12.169  89.188  1.000 102.677 ? 525 LYS AAA N   1 ? 
ATOM   3870 C  CA  . LYS A 1 525 ? 7.380   12.439  90.579  1.000 105.991 ? 525 LYS AAA CA  1 ? 
ATOM   3871 C  C   . LYS A 1 525 ? 6.555   11.234  91.069  1.000 96.608  ? 525 LYS AAA C   1 ? 
ATOM   3872 O  O   . LYS A 1 525 ? 6.917   10.594  92.071  1.000 93.234  ? 525 LYS AAA O   1 ? 
ATOM   3873 C  CB  . LYS A 1 525 ? 6.620   13.767  90.676  1.000 117.216 ? 525 LYS AAA CB  1 ? 
ATOM   3874 C  CG  . LYS A 1 525 ? 6.424   14.297  92.091  1.000 125.921 ? 525 LYS AAA CG  1 ? 
ATOM   3875 C  CD  . LYS A 1 525 ? 6.275   15.801  92.157  1.000 129.893 ? 525 LYS AAA CD  1 ? 
ATOM   3876 C  CE  . LYS A 1 525 ? 5.765   16.279  93.498  1.000 129.200 ? 525 LYS AAA CE  1 ? 
ATOM   3877 N  NZ  . LYS A 1 525 ? 6.285   17.625  93.830  1.000 131.024 ? 525 LYS AAA NZ  1 ? 
ATOM   3878 N  N   . GLN A 1 526 ? 5.495   10.902  90.330  1.000 87.606  ? 526 GLN AAA N   1 ? 
ATOM   3879 C  CA  . GLN A 1 526 ? 4.536   9.830   90.703  1.000 81.367  ? 526 GLN AAA CA  1 ? 
ATOM   3880 C  C   . GLN A 1 526 ? 5.256   8.508   90.888  1.000 78.195  ? 526 GLN AAA C   1 ? 
ATOM   3881 O  O   . GLN A 1 526 ? 5.153   7.875   91.945  1.000 79.715  ? 526 GLN AAA O   1 ? 
ATOM   3882 C  CB  . GLN A 1 526 ? 3.464   9.704   89.617  1.000 80.342  ? 526 GLN AAA CB  1 ? 
ATOM   3883 C  CG  . GLN A 1 526 ? 2.346   10.733  89.744  1.000 82.462  ? 526 GLN AAA CG  1 ? 
ATOM   3884 C  CD  . GLN A 1 526 ? 1.331   10.637  88.629  1.000 82.943  ? 526 GLN AAA CD  1 ? 
ATOM   3885 O  OE1 . GLN A 1 526 ? 1.612   10.103  87.560  1.000 83.127  ? 526 GLN AAA OE1 1 ? 
ATOM   3886 N  NE2 . GLN A 1 526 ? 0.139   11.163  88.866  1.000 83.621  ? 526 GLN AAA NE2 1 ? 
ATOM   3887 N  N   . THR A 1 527 ? 5.987   8.112   89.864  1.000 80.136  ? 527 THR AAA N   1 ? 
ATOM   3888 C  CA  . THR A 1 527 ? 6.838   6.906   89.916  1.000 85.913  ? 527 THR AAA CA  1 ? 
ATOM   3889 C  C   . THR A 1 527 ? 7.619   6.860   91.232  1.000 86.514  ? 527 THR AAA C   1 ? 
ATOM   3890 O  O   . THR A 1 527 ? 7.600   5.839   91.950  1.000 83.474  ? 527 THR AAA O   1 ? 
ATOM   3891 C  CB  . THR A 1 527 ? 7.772   6.850   88.699  1.000 88.651  ? 527 THR AAA CB  1 ? 
ATOM   3892 O  OG1 . THR A 1 527 ? 6.954   6.793   87.529  1.000 85.878  ? 527 THR AAA OG1 1 ? 
ATOM   3893 C  CG2 . THR A 1 527 ? 8.720   5.670   88.729  1.000 89.748  ? 527 THR AAA CG2 1 ? 
ATOM   3894 N  N   . ALA A 1 528 ? 8.304   7.948   91.544  1.000 84.664  ? 528 ALA AAA N   1 ? 
ATOM   3895 C  CA  . ALA A 1 528 ? 9.014   8.041   92.824  1.000 80.065  ? 528 ALA AAA CA  1 ? 
ATOM   3896 C  C   . ALA A 1 528 ? 8.035   7.806   93.971  1.000 77.376  ? 528 ALA AAA C   1 ? 
ATOM   3897 O  O   . ALA A 1 528 ? 8.303   6.965   94.833  1.000 73.860  ? 528 ALA AAA O   1 ? 
ATOM   3898 C  CB  . ALA A 1 528 ? 9.703   9.374   92.945  1.000 82.944  ? 528 ALA AAA CB  1 ? 
ATOM   3899 N  N   . LEU A 1 529 ? 6.913   8.522   93.957  1.000 78.603  ? 529 LEU AAA N   1 ? 
ATOM   3900 C  CA  . LEU A 1 529 ? 5.868   8.382   95.005  1.000 78.709  ? 529 LEU AAA CA  1 ? 
ATOM   3901 C  C   . LEU A 1 529 ? 5.560   6.911   95.292  1.000 78.249  ? 529 LEU AAA C   1 ? 
ATOM   3902 O  O   . LEU A 1 529 ? 5.495   6.480   96.470  1.000 74.854  ? 529 LEU AAA O   1 ? 
ATOM   3903 C  CB  . LEU A 1 529 ? 4.608   9.144   94.582  1.000 80.429  ? 529 LEU AAA CB  1 ? 
ATOM   3904 C  CG  . LEU A 1 529 ? 3.496   9.209   95.626  1.000 82.878  ? 529 LEU AAA CG  1 ? 
ATOM   3905 C  CD1 . LEU A 1 529 ? 3.984   9.875   96.903  1.000 85.175  ? 529 LEU AAA CD1 1 ? 
ATOM   3906 C  CD2 . LEU A 1 529 ? 2.282   9.940   95.071  1.000 84.460  ? 529 LEU AAA CD2 1 ? 
ATOM   3907 N  N   . VAL A 1 530 ? 5.386   6.130   94.244  1.000 79.668  ? 530 VAL AAA N   1 ? 
ATOM   3908 C  CA  . VAL A 1 530 ? 5.068   4.701   94.446  1.000 80.565  ? 530 VAL AAA CA  1 ? 
ATOM   3909 C  C   . VAL A 1 530 ? 6.198   4.061   95.248  1.000 81.594  ? 530 VAL AAA C   1 ? 
ATOM   3910 O  O   . VAL A 1 530 ? 5.944   3.382   96.236  1.000 81.264  ? 530 VAL AAA O   1 ? 
ATOM   3911 C  CB  . VAL A 1 530 ? 4.841   3.966   93.110  1.000 80.725  ? 530 VAL AAA CB  1 ? 
ATOM   3912 C  CG1 . VAL A 1 530 ? 4.623   2.475   93.315  1.000 82.533  ? 530 VAL AAA CG1 1 ? 
ATOM   3913 C  CG2 . VAL A 1 530 ? 3.674   4.553   92.333  1.000 80.823  ? 530 VAL AAA CG2 1 ? 
ATOM   3914 N  N   . GLU A 1 531 ? 7.433   4.310   94.856  1.000 86.789  ? 531 GLU AAA N   1 ? 
ATOM   3915 C  CA  . GLU A 1 531 ? 8.577   3.651   95.514  1.000 95.123  ? 531 GLU AAA CA  1 ? 
ATOM   3916 C  C   . GLU A 1 531 ? 8.631   4.091   96.956  1.000 100.960 ? 531 GLU AAA C   1 ? 
ATOM   3917 O  O   . GLU A 1 531 ? 8.912   3.293   97.854  1.000 94.986  ? 531 GLU AAA O   1 ? 
ATOM   3918 C  CB  . GLU A 1 531 ? 9.863   3.980   94.762  1.000 99.177  ? 531 GLU AAA CB  1 ? 
ATOM   3919 C  CG  . GLU A 1 531 ? 9.919   3.340   93.389  1.000 102.833 ? 531 GLU AAA CG  1 ? 
ATOM   3920 C  CD  . GLU A 1 531 ? 9.832   1.820   93.392  1.000 104.795 ? 531 GLU AAA CD  1 ? 
ATOM   3921 O  OE1 . GLU A 1 531 ? 9.916   1.218   94.486  1.000 103.043 ? 531 GLU AAA OE1 1 ? 
ATOM   3922 O  OE2 . GLU A 1 531 ? 9.688   1.236   92.297  1.000 109.102 ? 531 GLU AAA OE2 1 ? 
ATOM   3923 N  N   . LEU A 1 532 ? 8.364   5.363   97.124  1.000 111.084 ? 532 LEU AAA N   1 ? 
ATOM   3924 C  CA  . LEU A 1 532 ? 8.291   5.975   98.439  1.000 112.451 ? 532 LEU AAA CA  1 ? 
ATOM   3925 C  C   . LEU A 1 532 ? 7.251   5.259   99.301  1.000 107.047 ? 532 LEU AAA C   1 ? 
ATOM   3926 O  O   . LEU A 1 532 ? 7.537   4.990   100.471 1.000 109.042 ? 532 LEU AAA O   1 ? 
ATOM   3927 C  CB  . LEU A 1 532 ? 7.932   7.456   98.272  1.000 120.707 ? 532 LEU AAA CB  1 ? 
ATOM   3928 C  CG  . LEU A 1 532 ? 8.637   8.422   99.221  1.000 127.155 ? 532 LEU AAA CG  1 ? 
ATOM   3929 C  CD1 . LEU A 1 532 ? 8.098   9.833   99.038  1.000 131.820 ? 532 LEU AAA CD1 1 ? 
ATOM   3930 C  CD2 . LEU A 1 532 ? 8.493   7.974   100.669 1.000 130.721 ? 532 LEU AAA CD2 1 ? 
ATOM   3931 N  N   . VAL A 1 533 ? 6.077   4.942   98.749  1.000 99.883  ? 533 VAL AAA N   1 ? 
ATOM   3932 C  CA  . VAL A 1 533 ? 5.065   4.161   99.531  1.000 101.708 ? 533 VAL AAA CA  1 ? 
ATOM   3933 C  C   . VAL A 1 533 ? 5.546   2.732   99.766  1.000 98.642  ? 533 VAL AAA C   1 ? 
ATOM   3934 O  O   . VAL A 1 533 ? 5.608   2.264   100.915 1.000 96.408  ? 533 VAL AAA O   1 ? 
ATOM   3935 C  CB  . VAL A 1 533 ? 3.670   4.166   98.871  1.000 109.345 ? 533 VAL AAA CB  1 ? 
ATOM   3936 C  CG1 . VAL A 1 533 ? 2.686   3.262   99.609  1.000 109.526 ? 533 VAL AAA CG1 1 ? 
ATOM   3937 C  CG2 . VAL A 1 533 ? 3.098   5.572   98.757  1.000 113.720 ? 533 VAL AAA CG2 1 ? 
ATOM   3938 N  N   . LYS A 1 534 ? 5.874   2.040   98.690  1.000 103.269 ? 534 LYS AAA N   1 ? 
ATOM   3939 C  CA  . LYS A 1 534 ? 6.468   0.697   98.793  1.000 108.875 ? 534 LYS AAA CA  1 ? 
ATOM   3940 C  C   . LYS A 1 534 ? 7.554   0.666   99.873  1.000 117.960 ? 534 LYS AAA C   1 ? 
ATOM   3941 O  O   . LYS A 1 534 ? 7.769   -0.400  100.469 1.000 119.857 ? 534 LYS AAA O   1 ? 
ATOM   3942 C  CB  . LYS A 1 534 ? 7.075   0.272   97.451  1.000 104.739 ? 534 LYS AAA CB  1 ? 
ATOM   3943 C  CG  . LYS A 1 534 ? 6.067   -0.096  96.372  1.000 99.714  ? 534 LYS AAA CG  1 ? 
ATOM   3944 C  CD  . LYS A 1 534 ? 6.694   -0.705  95.142  1.000 96.548  ? 534 LYS AAA CD  1 ? 
ATOM   3945 C  CE  . LYS A 1 534 ? 5.667   -1.103  94.106  1.000 97.005  ? 534 LYS AAA CE  1 ? 
ATOM   3946 N  NZ  . LYS A 1 534 ? 6.301   -1.723  92.920  1.000 98.026  ? 534 LYS AAA NZ  1 ? 
ATOM   3947 N  N   . HIS A 1 535 ? 8.252   1.771   100.120 1.000 128.773 ? 535 HIS AAA N   1 ? 
ATOM   3948 C  CA  . HIS A 1 535 ? 9.305   1.773   101.163 1.000 140.319 ? 535 HIS AAA CA  1 ? 
ATOM   3949 C  C   . HIS A 1 535 ? 8.740   1.688   102.582 1.000 138.743 ? 535 HIS AAA C   1 ? 
ATOM   3950 O  O   . HIS A 1 535 ? 9.073   0.751   103.307 1.000 139.270 ? 535 HIS AAA O   1 ? 
ATOM   3951 C  CB  . HIS A 1 535 ? 10.237  2.988   101.023 1.000 155.072 ? 535 HIS AAA CB  1 ? 
ATOM   3952 C  CG  . HIS A 1 535 ? 11.439  2.927   101.915 1.000 167.926 ? 535 HIS AAA CG  1 ? 
ATOM   3953 N  ND1 . HIS A 1 535 ? 12.399  1.938   101.798 1.000 173.647 ? 535 HIS AAA ND1 1 ? 
ATOM   3954 C  CD2 . HIS A 1 535 ? 11.846  3.723   102.931 1.000 170.474 ? 535 HIS AAA CD2 1 ? 
ATOM   3955 C  CE1 . HIS A 1 535 ? 13.340  2.126   102.703 1.000 169.214 ? 535 HIS AAA CE1 1 ? 
ATOM   3956 N  NE2 . HIS A 1 535 ? 13.027  3.217   103.411 1.000 164.242 ? 535 HIS AAA NE2 1 ? 
ATOM   3957 N  N   . LYS A 1 536 ? 7.923   2.653   102.991 1.000 135.564 ? 536 LYS AAA N   1 ? 
ATOM   3958 C  CA  . LYS A 1 536 ? 7.305   2.638   104.342 1.000 132.847 ? 536 LYS AAA CA  1 ? 
ATOM   3959 C  C   . LYS A 1 536 ? 5.776   2.676   104.248 1.000 138.084 ? 536 LYS AAA C   1 ? 
ATOM   3960 O  O   . LYS A 1 536 ? 5.169   3.708   104.528 1.000 146.327 ? 536 LYS AAA O   1 ? 
ATOM   3961 C  CB  . LYS A 1 536 ? 7.835   3.810   105.173 1.000 127.319 ? 536 LYS AAA CB  1 ? 
ATOM   3962 N  N   . PRO A 1 537 ? 5.134   1.539   103.872 1.000 138.583 ? 537 PRO AAA N   1 ? 
ATOM   3963 C  CA  . PRO A 1 537 ? 3.680   1.470   103.693 1.000 136.268 ? 537 PRO AAA CA  1 ? 
ATOM   3964 C  C   . PRO A 1 537 ? 2.887   2.096   104.844 1.000 136.118 ? 537 PRO AAA C   1 ? 
ATOM   3965 O  O   . PRO A 1 537 ? 1.907   2.788   104.608 1.000 141.344 ? 537 PRO AAA O   1 ? 
ATOM   3966 C  CB  . PRO A 1 537 ? 3.354   -0.031  103.640 1.000 135.176 ? 537 PRO AAA CB  1 ? 
ATOM   3967 C  CG  . PRO A 1 537 ? 4.660   -0.704  103.269 1.000 136.696 ? 537 PRO AAA CG  1 ? 
ATOM   3968 C  CD  . PRO A 1 537 ? 5.765   0.215   103.750 1.000 137.183 ? 537 PRO AAA CD  1 ? 
ATOM   3969 N  N   . LYS A 1 538 ? 3.338   1.847   106.069 1.000 133.844 ? 538 LYS AAA N   1 ? 
ATOM   3970 C  CA  . LYS A 1 538 ? 2.745   2.467   107.278 1.000 127.409 ? 538 LYS AAA CA  1 ? 
ATOM   3971 C  C   . LYS A 1 538 ? 3.270   3.895   107.389 1.000 129.874 ? 538 LYS AAA C   1 ? 
ATOM   3972 O  O   . LYS A 1 538 ? 3.754   4.273   108.476 1.000 128.539 ? 538 LYS AAA O   1 ? 
ATOM   3973 C  CB  . LYS A 1 538 ? 3.072   1.635   108.524 1.000 119.120 ? 538 LYS AAA CB  1 ? 
ATOM   3974 N  N   . ALA A 1 539 ? 3.189   4.642   106.285 1.000 133.025 ? 539 ALA AAA N   1 ? 
ATOM   3975 C  CA  . ALA A 1 539 ? 3.439   6.096   106.257 1.000 130.506 ? 539 ALA AAA CA  1 ? 
ATOM   3976 C  C   . ALA A 1 539 ? 2.196   6.875   106.646 1.000 131.929 ? 539 ALA AAA C   1 ? 
ATOM   3977 O  O   . ALA A 1 539 ? 1.068   6.393   106.498 1.000 127.823 ? 539 ALA AAA O   1 ? 
ATOM   3978 C  CB  . ALA A 1 539 ? 3.918   6.512   104.886 1.000 128.326 ? 539 ALA AAA CB  1 ? 
ATOM   3979 N  N   . THR A 1 540 ? 2.438   8.101   107.073 1.000 139.108 ? 540 THR AAA N   1 ? 
ATOM   3980 C  CA  . THR A 1 540 ? 1.404   9.083   107.394 1.000 146.279 ? 540 THR AAA CA  1 ? 
ATOM   3981 C  C   . THR A 1 540 ? 1.456   10.149  106.324 1.000 144.183 ? 540 THR AAA C   1 ? 
ATOM   3982 O  O   . THR A 1 540 ? 2.547   10.639  106.011 1.000 140.114 ? 540 THR AAA O   1 ? 
ATOM   3983 C  CB  . THR A 1 540 ? 1.617   9.724   108.773 1.000 151.909 ? 540 THR AAA CB  1 ? 
ATOM   3984 O  OG1 . THR A 1 540 ? 1.978   8.701   109.701 1.000 158.728 ? 540 THR AAA OG1 1 ? 
ATOM   3985 C  CG2 . THR A 1 540 ? 0.396   10.464  109.276 1.000 151.341 ? 540 THR AAA CG2 1 ? 
ATOM   3986 N  N   . LYS A 1 541 ? 0.296   10.521  105.828 1.000 143.398 ? 541 LYS AAA N   1 ? 
ATOM   3987 C  CA  . LYS A 1 541 ? 0.178   11.585  104.813 1.000 147.614 ? 541 LYS AAA CA  1 ? 
ATOM   3988 C  C   . LYS A 1 541 ? 1.190   12.714  105.077 1.000 157.829 ? 541 LYS AAA C   1 ? 
ATOM   3989 O  O   . LYS A 1 541 ? 1.728   13.250  104.084 1.000 164.773 ? 541 LYS AAA O   1 ? 
ATOM   3990 C  CB  . LYS A 1 541 ? -1.248  12.145  104.800 1.000 146.067 ? 541 LYS AAA CB  1 ? 
ATOM   3991 N  N   . GLU A 1 542 ? 1.385   13.104  106.342 1.000 165.482 ? 542 GLU AAA N   1 ? 
ATOM   3992 C  CA  . GLU A 1 542 ? 2.318   14.195  106.742 1.000 163.655 ? 542 GLU AAA CA  1 ? 
ATOM   3993 C  C   . GLU A 1 542 ? 3.760   13.759  106.456 1.000 152.224 ? 542 GLU AAA C   1 ? 
ATOM   3994 O  O   . GLU A 1 542 ? 4.460   14.493  105.727 1.000 163.884 ? 542 GLU AAA O   1 ? 
ATOM   3995 C  CB  . GLU A 1 542 ? 2.123   14.583  108.212 1.000 167.717 ? 542 GLU AAA CB  1 ? 
ATOM   3996 C  CG  . GLU A 1 542 ? 1.264   15.823  108.412 1.000 165.552 ? 542 GLU AAA CG  1 ? 
ATOM   3997 C  CD  . GLU A 1 542 ? -0.022  15.864  107.602 1.000 165.744 ? 542 GLU AAA CD  1 ? 
ATOM   3998 O  OE1 . GLU A 1 542 ? -0.890  14.998  107.829 1.000 172.394 ? 542 GLU AAA OE1 1 ? 
ATOM   3999 O  OE2 . GLU A 1 542 ? -0.146  16.758  106.740 1.000 159.860 ? 542 GLU AAA OE2 1 ? 
ATOM   4000 N  N   . GLN A 1 543 ? 4.201   12.646  107.041 1.000 129.435 ? 543 GLN AAA N   1 ? 
ATOM   4001 C  CA  . GLN A 1 543 ? 5.579   12.124  106.804 1.000 120.738 ? 543 GLN AAA CA  1 ? 
ATOM   4002 C  C   . GLN A 1 543 ? 5.770   11.629  105.368 1.000 117.465 ? 543 GLN AAA C   1 ? 
ATOM   4003 O  O   . GLN A 1 543 ? 6.890   11.221  105.033 1.000 106.652 ? 543 GLN AAA O   1 ? 
ATOM   4004 C  CB  . GLN A 1 543 ? 5.970   11.069  107.845 1.000 119.085 ? 543 GLN AAA CB  1 ? 
ATOM   4005 C  CG  . GLN A 1 543 ? 5.288   9.723   107.667 1.000 120.312 ? 543 GLN AAA CG  1 ? 
ATOM   4006 C  CD  . GLN A 1 543 ? 5.548   8.775   108.814 1.000 118.380 ? 543 GLN AAA CD  1 ? 
ATOM   4007 O  OE1 . GLN A 1 543 ? 5.056   8.963   109.923 1.000 122.809 ? 543 GLN AAA OE1 1 ? 
ATOM   4008 N  NE2 . GLN A 1 543 ? 6.313   7.727   108.551 1.000 108.738 ? 543 GLN AAA NE2 1 ? 
ATOM   4009 N  N   . LEU A 1 544 ? 4.716   11.647  104.554 1.000 123.982 ? 544 LEU AAA N   1 ? 
ATOM   4010 C  CA  . LEU A 1 544 ? 4.850   11.601  103.082 1.000 129.073 ? 544 LEU AAA CA  1 ? 
ATOM   4011 C  C   . LEU A 1 544 ? 5.056   13.002  102.546 1.000 124.043 ? 544 LEU AAA C   1 ? 
ATOM   4012 O  O   . LEU A 1 544 ? 6.015   13.234  101.815 1.000 112.485 ? 544 LEU AAA O   1 ? 
ATOM   4013 C  CB  . LEU A 1 544 ? 3.603   10.980  102.439 1.000 142.013 ? 544 LEU AAA CB  1 ? 
ATOM   4014 C  CG  . LEU A 1 544 ? 3.488   9.456   102.492 1.000 149.511 ? 544 LEU AAA CG  1 ? 
ATOM   4015 C  CD1 . LEU A 1 544 ? 2.248   8.993   101.737 1.000 152.846 ? 544 LEU AAA CD1 1 ? 
ATOM   4016 C  CD2 . LEU A 1 544 ? 4.733   8.778   101.934 1.000 145.547 ? 544 LEU AAA CD2 1 ? 
ATOM   4017 N  N   . LYS A 1 545 ? 4.164   13.915  102.897 1.000 126.958 ? 545 LYS AAA N   1 ? 
ATOM   4018 C  CA  . LYS A 1 545 ? 4.307   15.317  102.454 1.000 126.350 ? 545 LYS AAA CA  1 ? 
ATOM   4019 C  C   . LYS A 1 545 ? 5.769   15.712  102.625 1.000 128.651 ? 545 LYS AAA C   1 ? 
ATOM   4020 O  O   . LYS A 1 545 ? 6.397   16.260  101.692 1.000 131.019 ? 545 LYS AAA O   1 ? 
ATOM   4021 C  CB  . LYS A 1 545 ? 3.366   16.230  103.247 1.000 119.768 ? 545 LYS AAA CB  1 ? 
ATOM   4022 N  N   . ALA A 1 546 ? 6.303   15.351  103.783 1.000 131.219 ? 546 ALA AAA N   1 ? 
ATOM   4023 C  CA  . ALA A 1 546 ? 7.681   15.650  104.201 1.000 133.193 ? 546 ALA AAA CA  1 ? 
ATOM   4024 C  C   . ALA A 1 546 ? 8.733   15.052  103.277 1.000 141.208 ? 546 ALA AAA C   1 ? 
ATOM   4025 O  O   . ALA A 1 546 ? 9.725   15.722  102.956 1.000 145.796 ? 546 ALA AAA O   1 ? 
ATOM   4026 C  CB  . ALA A 1 546 ? 7.888   15.174  105.620 1.000 130.012 ? 546 ALA AAA CB  1 ? 
ATOM   4027 N  N   . VAL A 1 547 ? 8.539   13.809  102.872 1.000 148.217 ? 547 VAL AAA N   1 ? 
ATOM   4028 C  CA  . VAL A 1 547 ? 9.547   13.114  102.036 1.000 152.482 ? 547 VAL AAA CA  1 ? 
ATOM   4029 C  C   . VAL A 1 547 ? 9.394   13.554  100.578 1.000 157.892 ? 547 VAL AAA C   1 ? 
ATOM   4030 O  O   . VAL A 1 547 ? 10.400  13.964  99.957  1.000 162.300 ? 547 VAL AAA O   1 ? 
ATOM   4031 C  CB  . VAL A 1 547 ? 9.493   11.582  102.190 1.000 151.081 ? 547 VAL AAA CB  1 ? 
ATOM   4032 C  CG1 . VAL A 1 547 ? 10.639  10.912  101.441 1.000 144.110 ? 547 VAL AAA CG1 1 ? 
ATOM   4033 C  CG2 . VAL A 1 547 ? 9.511   11.160  103.652 1.000 152.669 ? 547 VAL AAA CG2 1 ? 
ATOM   4034 N  N   . MET A 1 548 ? 8.171   13.474  100.052 1.000 158.763 ? 548 MET AAA N   1 ? 
ATOM   4035 C  CA  . MET A 1 548 ? 7.790   14.097  98.760  1.000 158.135 ? 548 MET AAA CA  1 ? 
ATOM   4036 C  C   . MET A 1 548 ? 8.487   15.451  98.622  1.000 168.675 ? 548 MET AAA C   1 ? 
ATOM   4037 O  O   . MET A 1 548 ? 9.342   15.622  97.743  1.000 188.543 ? 548 MET AAA O   1 ? 
ATOM   4038 C  CB  . MET A 1 548 ? 6.269   14.282  98.638  1.000 148.124 ? 548 MET AAA CB  1 ? 
ATOM   4039 C  CG  . MET A 1 548 ? 5.687   13.802  97.310  1.000 140.444 ? 548 MET AAA CG  1 ? 
ATOM   4040 S  SD  . MET A 1 548 ? 3.911   14.169  97.131  1.000 131.708 ? 548 MET AAA SD  1 ? 
ATOM   4041 C  CE  . MET A 1 548 ? 3.949   15.606  96.064  1.000 126.598 ? 548 MET AAA CE  1 ? 
ATOM   4042 N  N   . ASP A 1 549 ? 8.130   16.388  99.489  1.000 168.809 ? 549 ASP AAA N   1 ? 
ATOM   4043 C  CA  . ASP A 1 549 ? 8.645   17.766  99.351  1.000 172.201 ? 549 ASP AAA CA  1 ? 
ATOM   4044 C  C   . ASP A 1 549 ? 10.173  17.715  99.294  1.000 164.168 ? 549 ASP AAA C   1 ? 
ATOM   4045 O  O   . ASP A 1 549 ? 10.771  18.111  98.277  1.000 169.336 ? 549 ASP AAA O   1 ? 
ATOM   4046 C  CB  . ASP A 1 549 ? 8.094   18.686  100.443 1.000 183.136 ? 549 ASP AAA CB  1 ? 
ATOM   4047 C  CG  . ASP A 1 549 ? 6.713   19.233  100.117 1.000 186.740 ? 549 ASP AAA CG  1 ? 
ATOM   4048 O  OD1 . ASP A 1 549 ? 6.617   20.067  99.192  1.000 188.872 ? 549 ASP AAA OD1 1 ? 
ATOM   4049 O  OD2 . ASP A 1 549 ? 5.743   18.811  100.777 1.000 190.320 ? 549 ASP AAA OD2 1 ? 
ATOM   4050 N  N   . ASP A 1 550 ? 10.783  17.167  100.329 1.000 151.829 ? 550 ASP AAA N   1 ? 
ATOM   4051 C  CA  . ASP A 1 550 ? 12.253  17.013  100.383 1.000 150.439 ? 550 ASP AAA CA  1 ? 
ATOM   4052 C  C   . ASP A 1 550 ? 12.788  16.714  98.994  1.000 157.281 ? 550 ASP AAA C   1 ? 
ATOM   4053 O  O   . ASP A 1 550 ? 13.605  17.485  98.443  1.000 162.178 ? 550 ASP AAA O   1 ? 
ATOM   4054 C  CB  . ASP A 1 550 ? 12.665  15.914  101.364 1.000 143.403 ? 550 ASP AAA CB  1 ? 
ATOM   4055 N  N   . PHE A 1 551 ? 12.284  15.640  98.414  1.000 164.828 ? 551 PHE AAA N   1 ? 
ATOM   4056 C  CA  . PHE A 1 551 ? 12.824  15.159  97.133  1.000 167.740 ? 551 PHE AAA CA  1 ? 
ATOM   4057 C  C   . PHE A 1 551 ? 12.591  16.141  95.985  1.000 164.544 ? 551 PHE AAA C   1 ? 
ATOM   4058 O  O   . PHE A 1 551 ? 13.500  16.325  95.156  1.000 167.132 ? 551 PHE AAA O   1 ? 
ATOM   4059 C  CB  . PHE A 1 551 ? 12.301  13.760  96.795  1.000 172.981 ? 551 PHE AAA CB  1 ? 
ATOM   4060 C  CG  . PHE A 1 551 ? 13.384  12.839  96.295  1.000 181.169 ? 551 PHE AAA CG  1 ? 
ATOM   4061 C  CD1 . PHE A 1 551 ? 13.922  13.005  95.028  1.000 189.196 ? 551 PHE AAA CD1 1 ? 
ATOM   4062 C  CD2 . PHE A 1 551 ? 13.902  11.839  97.106  1.000 183.020 ? 551 PHE AAA CD2 1 ? 
ATOM   4063 C  CE1 . PHE A 1 551 ? 14.935  12.175  94.572  1.000 193.289 ? 551 PHE AAA CE1 1 ? 
ATOM   4064 C  CE2 . PHE A 1 551 ? 14.915  11.008  96.648  1.000 186.133 ? 551 PHE AAA CE2 1 ? 
ATOM   4065 C  CZ  . PHE A 1 551 ? 15.429  11.177  95.382  1.000 190.902 ? 551 PHE AAA CZ  1 ? 
ATOM   4066 N  N   . ALA A 1 552 ? 11.399  16.721  95.925  1.000 164.516 ? 552 ALA AAA N   1 ? 
ATOM   4067 C  CA  . ALA A 1 552 ? 11.068  17.722  94.892  1.000 164.507 ? 552 ALA AAA CA  1 ? 
ATOM   4068 C  C   . ALA A 1 552 ? 12.038  18.889  95.014  1.000 162.729 ? 552 ALA AAA C   1 ? 
ATOM   4069 O  O   . ALA A 1 552 ? 12.557  19.377  93.993  1.000 176.632 ? 552 ALA AAA O   1 ? 
ATOM   4070 C  CB  . ALA A 1 552 ? 9.636   18.172  95.048  1.000 164.958 ? 552 ALA AAA CB  1 ? 
ATOM   4071 N  N   . ALA A 1 553 ? 12.284  19.314  96.242  1.000 153.202 ? 553 ALA AAA N   1 ? 
ATOM   4072 C  CA  . ALA A 1 553 ? 13.287  20.355  96.507  1.000 147.451 ? 553 ALA AAA CA  1 ? 
ATOM   4073 C  C   . ALA A 1 553 ? 14.670  19.920  96.030  1.000 140.623 ? 553 ALA AAA C   1 ? 
ATOM   4074 O  O   . ALA A 1 553 ? 15.397  20.761  95.460  1.000 139.794 ? 553 ALA AAA O   1 ? 
ATOM   4075 C  CB  . ALA A 1 553 ? 13.307  20.693  97.979  1.000 146.942 ? 553 ALA AAA CB  1 ? 
ATOM   4076 N  N   . PHE A 1 554 ? 15.023  18.662  96.276  1.000 134.335 ? 554 PHE AAA N   1 ? 
ATOM   4077 C  CA  . PHE A 1 554 ? 16.303  18.077  95.819  1.000 132.929 ? 554 PHE AAA CA  1 ? 
ATOM   4078 C  C   . PHE A 1 554 ? 16.415  18.224  94.311  1.000 124.320 ? 554 PHE AAA C   1 ? 
ATOM   4079 O  O   . PHE A 1 554 ? 17.374  18.841  93.799  1.000 119.841 ? 554 PHE AAA O   1 ? 
ATOM   4080 C  CB  . PHE A 1 554 ? 16.427  16.611  96.237  1.000 137.450 ? 554 PHE AAA CB  1 ? 
ATOM   4081 C  CG  . PHE A 1 554 ? 17.655  15.922  95.700  1.000 139.878 ? 554 PHE AAA CG  1 ? 
ATOM   4082 C  CD1 . PHE A 1 554 ? 18.897  16.149  96.272  1.000 144.811 ? 554 PHE AAA CD1 1 ? 
ATOM   4083 C  CD2 . PHE A 1 554 ? 17.573  15.059  94.618  1.000 137.974 ? 554 PHE AAA CD2 1 ? 
ATOM   4084 C  CE1 . PHE A 1 554 ? 20.030  15.518  95.782  1.000 145.796 ? 554 PHE AAA CE1 1 ? 
ATOM   4085 C  CE2 . PHE A 1 554 ? 18.706  14.428  94.130  1.000 141.928 ? 554 PHE AAA CE2 1 ? 
ATOM   4086 C  CZ  . PHE A 1 554 ? 19.932  14.658  94.713  1.000 145.082 ? 554 PHE AAA CZ  1 ? 
ATOM   4087 N  N   . VAL A 1 555 ? 15.428  17.706  93.598  1.000 118.465 ? 555 VAL AAA N   1 ? 
ATOM   4088 C  CA  . VAL A 1 555 ? 15.470  17.815  92.119  1.000 115.984 ? 555 VAL AAA CA  1 ? 
ATOM   4089 C  C   . VAL A 1 555 ? 15.484  19.282  91.695  1.000 117.316 ? 555 VAL AAA C   1 ? 
ATOM   4090 O  O   . VAL A 1 555 ? 16.210  19.617  90.757  1.000 113.287 ? 555 VAL AAA O   1 ? 
ATOM   4091 C  CB  . VAL A 1 555 ? 14.335  17.038  91.419  1.000 119.715 ? 555 VAL AAA CB  1 ? 
ATOM   4092 C  CG1 . VAL A 1 555 ? 12.975  17.708  91.542  1.000 119.157 ? 555 VAL AAA CG1 1 ? 
ATOM   4093 C  CG2 . VAL A 1 555 ? 14.666  16.793  89.955  1.000 122.505 ? 555 VAL AAA CG2 1 ? 
ATOM   4094 N  N   . GLU A 1 556 ? 14.721  20.135  92.374  1.000 129.737 ? 556 GLU AAA N   1 ? 
ATOM   4095 C  CA  . GLU A 1 556 ? 14.673  21.579  92.034  1.000 138.540 ? 556 GLU AAA CA  1 ? 
ATOM   4096 C  C   . GLU A 1 556 ? 16.058  22.200  92.112  1.000 143.296 ? 556 GLU AAA C   1 ? 
ATOM   4097 O  O   . GLU A 1 556 ? 16.498  22.857  91.163  1.000 152.317 ? 556 GLU AAA O   1 ? 
ATOM   4098 C  CB  . GLU A 1 556 ? 13.723  22.326  92.974  1.000 138.254 ? 556 GLU AAA CB  1 ? 
ATOM   4099 N  N   . LYS A 1 557 ? 16.729  21.982  93.228  1.000 141.109 ? 557 LYS AAA N   1 ? 
ATOM   4100 C  CA  . LYS A 1 557 ? 18.102  22.473  93.422  1.000 139.240 ? 557 LYS AAA CA  1 ? 
ATOM   4101 C  C   . LYS A 1 557 ? 19.019  21.854  92.379  1.000 139.324 ? 557 LYS AAA C   1 ? 
ATOM   4102 O  O   . LYS A 1 557 ? 19.669  22.594  91.628  1.000 128.018 ? 557 LYS AAA O   1 ? 
ATOM   4103 C  CB  . LYS A 1 557 ? 18.591  22.169  94.841  1.000 139.632 ? 557 LYS AAA CB  1 ? 
ATOM   4104 C  CG  . LYS A 1 557 ? 17.945  23.015  95.930  1.000 148.218 ? 557 LYS AAA CG  1 ? 
ATOM   4105 C  CD  . LYS A 1 557 ? 18.217  24.502  95.791  1.000 154.409 ? 557 LYS AAA CD  1 ? 
ATOM   4106 C  CE  . LYS A 1 557 ? 17.392  25.351  96.735  1.000 160.152 ? 557 LYS AAA CE  1 ? 
ATOM   4107 N  NZ  . LYS A 1 557 ? 17.378  26.773  96.318  1.000 165.814 ? 557 LYS AAA NZ  1 ? 
ATOM   4108 N  N   . CYS A 1 558 ? 19.056  20.530  92.321  1.000 153.753 ? 558 CYS AAA N   1 ? 
ATOM   4109 C  CA  . CYS A 1 558 ? 19.956  19.830  91.377  1.000 170.228 ? 558 CYS AAA CA  1 ? 
ATOM   4110 C  C   . CYS A 1 558 ? 19.638  20.139  89.909  1.000 167.812 ? 558 CYS AAA C   1 ? 
ATOM   4111 O  O   . CYS A 1 558 ? 20.465  19.790  89.039  1.000 165.971 ? 558 CYS AAA O   1 ? 
ATOM   4112 C  CB  . CYS A 1 558 ? 19.984  18.328  91.644  1.000 187.595 ? 558 CYS AAA CB  1 ? 
ATOM   4113 S  SG  . CYS A 1 558 ? 20.977  17.856  93.090  1.000 210.099 ? 558 CYS AAA SG  1 ? 
ATOM   4114 N  N   . CYS A 1 559 ? 18.502  20.772  89.624  1.000 169.016 ? 559 CYS AAA N   1 ? 
ATOM   4115 C  CA  . CYS A 1 559 ? 18.246  21.346  88.282  1.000 167.854 ? 559 CYS AAA CA  1 ? 
ATOM   4116 C  C   . CYS A 1 559 ? 18.994  22.655  88.054  1.000 177.002 ? 559 CYS AAA C   1 ? 
ATOM   4117 O  O   . CYS A 1 559 ? 19.516  22.865  86.942  1.000 185.747 ? 559 CYS AAA O   1 ? 
ATOM   4118 C  CB  . CYS A 1 559 ? 16.759  21.592  88.056  1.000 159.786 ? 559 CYS AAA CB  1 ? 
ATOM   4119 S  SG  . CYS A 1 559 ? 15.829  20.063  87.793  1.000 157.541 ? 559 CYS AAA SG  1 ? 
ATOM   4120 N  N   . LYS A 1 560 ? 19.022  23.520  89.072  1.000 181.622 ? 560 LYS AAA N   1 ? 
ATOM   4121 C  CA  . LYS A 1 560 ? 19.647  24.870  89.031  1.000 181.930 ? 560 LYS AAA CA  1 ? 
ATOM   4122 C  C   . LYS A 1 560 ? 21.021  24.874  88.353  1.000 188.172 ? 560 LYS AAA C   1 ? 
ATOM   4123 O  O   . LYS A 1 560 ? 21.308  25.862  87.650  1.000 194.668 ? 560 LYS AAA O   1 ? 
ATOM   4124 C  CB  . LYS A 1 560 ? 19.771  25.434  90.451  1.000 173.727 ? 560 LYS AAA CB  1 ? 
ATOM   4125 N  N   . ALA A 1 561 ? 21.855  23.861  88.612  1.000 191.889 ? 561 ALA AAA N   1 ? 
ATOM   4126 C  CA  . ALA A 1 561 ? 23.058  23.525  87.800  1.000 193.908 ? 561 ALA AAA CA  1 ? 
ATOM   4127 C  C   . ALA A 1 561 ? 24.404  23.770  88.508  1.000 209.287 ? 561 ALA AAA C   1 ? 
ATOM   4128 O  O   . ALA A 1 561 ? 24.458  24.197  89.690  1.000 216.543 ? 561 ALA AAA O   1 ? 
ATOM   4129 C  CB  . ALA A 1 561 ? 23.021  24.243  86.466  1.000 182.139 ? 561 ALA AAA CB  1 ? 
ATOM   4130 N  N   . ASP A 1 562 ? 25.480  23.453  87.772  1.000 229.299 ? 562 ASP AAA N   1 ? 
ATOM   4131 C  CA  . ASP A 1 562 ? 26.901  23.379  88.216  1.000 239.987 ? 562 ASP AAA CA  1 ? 
ATOM   4132 C  C   . ASP A 1 562 ? 27.572  22.244  87.426  1.000 247.296 ? 562 ASP AAA C   1 ? 
ATOM   4133 O  O   . ASP A 1 562 ? 27.928  22.475  86.252  1.000 265.717 ? 562 ASP AAA O   1 ? 
ATOM   4134 C  CB  . ASP A 1 562 ? 27.018  23.177  89.730  1.000 241.456 ? 562 ASP AAA CB  1 ? 
ATOM   4135 N  N   . ASP A 1 563 ? 27.732  21.071  88.051  1.000 236.802 ? 563 ASP AAA N   1 ? 
ATOM   4136 C  CA  . ASP A 1 563 ? 27.989  19.766  87.383  1.000 224.359 ? 563 ASP AAA CA  1 ? 
ATOM   4137 C  C   . ASP A 1 563 ? 26.877  18.811  87.830  1.000 212.059 ? 563 ASP AAA C   1 ? 
ATOM   4138 O  O   . ASP A 1 563 ? 27.183  17.818  88.515  1.000 210.011 ? 563 ASP AAA O   1 ? 
ATOM   4139 C  CB  . ASP A 1 563 ? 29.394  19.244  87.697  1.000 221.763 ? 563 ASP AAA CB  1 ? 
ATOM   4140 N  N   . LYS A 1 564 ? 25.636  19.132  87.447  1.000 194.119 ? 564 LYS AAA N   1 ? 
ATOM   4141 C  CA  . LYS A 1 564 ? 24.360  18.547  87.949  1.000 184.241 ? 564 LYS AAA CA  1 ? 
ATOM   4142 C  C   . LYS A 1 564 ? 24.573  17.153  88.544  1.000 181.612 ? 564 LYS AAA C   1 ? 
ATOM   4143 O  O   . LYS A 1 564 ? 24.151  16.928  89.688  1.000 176.339 ? 564 LYS AAA O   1 ? 
ATOM   4144 C  CB  . LYS A 1 564 ? 23.347  18.449  86.807  1.000 184.625 ? 564 LYS AAA CB  1 ? 
ATOM   4145 C  CG  . LYS A 1 564 ? 22.730  19.774  86.387  1.000 188.284 ? 564 LYS AAA CG  1 ? 
ATOM   4146 C  CD  . LYS A 1 564 ? 22.498  19.889  84.900  1.000 193.313 ? 564 LYS AAA CD  1 ? 
ATOM   4147 C  CE  . LYS A 1 564 ? 21.755  21.153  84.524  1.000 192.899 ? 564 LYS AAA CE  1 ? 
ATOM   4148 N  NZ  . LYS A 1 564 ? 21.703  21.345  83.056  1.000 190.087 ? 564 LYS AAA NZ  1 ? 
ATOM   4149 N  N   . GLU A 1 565 ? 25.185  16.255  87.776  1.000 183.052 ? 565 GLU AAA N   1 ? 
ATOM   4150 C  CA  . GLU A 1 565 ? 25.367  14.823  88.137  1.000 186.692 ? 565 GLU AAA CA  1 ? 
ATOM   4151 C  C   . GLU A 1 565 ? 26.067  14.750  89.502  1.000 188.753 ? 565 GLU AAA C   1 ? 
ATOM   4152 O  O   . GLU A 1 565 ? 25.624  13.946  90.350  1.000 173.635 ? 565 GLU AAA O   1 ? 
ATOM   4153 C  CB  . GLU A 1 565 ? 26.136  14.104  87.026  1.000 187.971 ? 565 GLU AAA CB  1 ? 
ATOM   4154 C  CG  . GLU A 1 565 ? 25.788  14.587  85.624  1.000 189.961 ? 565 GLU AAA CG  1 ? 
ATOM   4155 C  CD  . GLU A 1 565 ? 26.181  13.653  84.492  1.000 197.565 ? 565 GLU AAA CD  1 ? 
ATOM   4156 O  OE1 . GLU A 1 565 ? 27.123  13.995  83.745  1.000 202.336 ? 565 GLU AAA OE1 1 ? 
ATOM   4157 O  OE2 . GLU A 1 565 ? 25.533  12.596  84.348  1.000 199.994 ? 565 GLU AAA OE2 1 ? 
ATOM   4158 N  N   . THR A 1 566 ? 27.099  15.583  89.700  1.000 199.498 ? 566 THR AAA N   1 ? 
ATOM   4159 C  CA  . THR A 1 566 ? 27.828  15.798  90.983  1.000 204.120 ? 566 THR AAA CA  1 ? 
ATOM   4160 C  C   . THR A 1 566 ? 26.827  16.172  92.083  1.000 199.756 ? 566 THR AAA C   1 ? 
ATOM   4161 O  O   . THR A 1 566 ? 26.980  15.666  93.210  1.000 194.372 ? 566 THR AAA O   1 ? 
ATOM   4162 C  CB  . THR A 1 566 ? 28.909  16.881  90.840  1.000 208.452 ? 566 THR AAA CB  1 ? 
ATOM   4163 O  OG1 . THR A 1 566 ? 29.496  16.775  89.542  1.000 215.096 ? 566 THR AAA OG1 1 ? 
ATOM   4164 C  CG2 . THR A 1 566 ? 29.995  16.782  91.890  1.000 208.821 ? 566 THR AAA CG2 1 ? 
ATOM   4165 N  N   . CYS A 1 567 ? 25.855  17.037  91.770  1.000 198.515 ? 567 CYS AAA N   1 ? 
ATOM   4166 C  CA  . CYS A 1 567 ? 24.726  17.408  92.667  1.000 202.105 ? 567 CYS AAA CA  1 ? 
ATOM   4167 C  C   . CYS A 1 567 ? 23.891  16.160  92.972  1.000 205.600 ? 567 CYS AAA C   1 ? 
ATOM   4168 O  O   . CYS A 1 567 ? 23.700  15.859  94.170  1.000 206.620 ? 567 CYS AAA O   1 ? 
ATOM   4169 C  CB  . CYS A 1 567 ? 23.833  18.481  92.051  1.000 203.379 ? 567 CYS AAA CB  1 ? 
ATOM   4170 S  SG  . CYS A 1 567 ? 22.580  19.136  93.188  1.000 214.842 ? 567 CYS AAA SG  1 ? 
ATOM   4171 N  N   . PHE A 1 568 ? 23.428  15.463  91.924  1.000 203.111 ? 568 PHE AAA N   1 ? 
ATOM   4172 C  CA  . PHE A 1 568 ? 22.556  14.259  92.014  1.000 199.619 ? 568 PHE AAA CA  1 ? 
ATOM   4173 C  C   . PHE A 1 568 ? 23.235  13.136  92.796  1.000 202.082 ? 568 PHE AAA C   1 ? 
ATOM   4174 O  O   . PHE A 1 568 ? 22.550  12.161  93.137  1.000 207.194 ? 568 PHE AAA O   1 ? 
ATOM   4175 C  CB  . PHE A 1 568 ? 22.100  13.808  90.620  1.000 189.085 ? 568 PHE AAA CB  1 ? 
ATOM   4176 C  CG  . PHE A 1 568 ? 20.884  14.531  90.087  1.000 177.894 ? 568 PHE AAA CG  1 ? 
ATOM   4177 C  CD1 . PHE A 1 568 ? 20.985  15.412  89.020  1.000 169.845 ? 568 PHE AAA CD1 1 ? 
ATOM   4178 C  CD2 . PHE A 1 568 ? 19.635  14.333  90.657  1.000 174.409 ? 568 PHE AAA CD2 1 ? 
ATOM   4179 C  CE1 . PHE A 1 568 ? 19.866  16.072  88.535  1.000 164.092 ? 568 PHE AAA CE1 1 ? 
ATOM   4180 C  CE2 . PHE A 1 568 ? 18.518  14.997  90.174  1.000 170.013 ? 568 PHE AAA CE2 1 ? 
ATOM   4181 C  CZ  . PHE A 1 568 ? 18.635  15.865  89.113  1.000 167.904 ? 568 PHE AAA CZ  1 ? 
ATOM   4182 N  N   . ALA A 1 569 ? 24.527  13.264  93.076  1.000 197.812 ? 569 ALA AAA N   1 ? 
ATOM   4183 C  CA  . ALA A 1 569 ? 25.208  12.433  94.104  1.000 197.862 ? 569 ALA AAA CA  1 ? 
ATOM   4184 C  C   . ALA A 1 569 ? 24.440  12.345  95.443  1.000 200.699 ? 569 ALA AAA C   1 ? 
ATOM   4185 O  O   . ALA A 1 569 ? 24.882  12.955  96.457  1.000 205.491 ? 569 ALA AAA O   1 ? 
ATOM   4186 C  CB  . ALA A 1 569 ? 26.604  12.965  94.331  1.000 194.614 ? 569 ALA AAA CB  1 ? 
ATOM   4187 N  N   . GLU A 1 570 ? 23.362  11.547  95.475  1.000 201.802 ? 570 GLU AAA N   1 ? 
ATOM   4188 C  CA  . GLU A 1 570 ? 22.646  11.085  96.695  1.000 204.745 ? 570 GLU AAA CA  1 ? 
ATOM   4189 C  C   . GLU A 1 570 ? 21.357  10.383  96.245  1.000 220.606 ? 570 GLU AAA C   1 ? 
ATOM   4190 O  O   . GLU A 1 570 ? 20.299  10.996  96.141  1.000 240.164 ? 570 GLU AAA O   1 ? 
ATOM   4191 C  CB  . GLU A 1 570 ? 22.331  12.226  97.674  1.000 194.266 ? 570 GLU AAA CB  1 ? 
ATOM   4192 C  CG  . GLU A 1 570 ? 22.433  11.834  99.145  1.000 186.746 ? 570 GLU AAA CG  1 ? 
ATOM   4193 C  CD  . GLU A 1 570 ? 21.416  10.828  99.661  1.000 185.962 ? 570 GLU AAA CD  1 ? 
ATOM   4194 O  OE1 . GLU A 1 570 ? 20.441  11.259  100.313 1.000 178.994 ? 570 GLU AAA OE1 1 ? 
ATOM   4195 O  OE2 . GLU A 1 570 ? 21.618  9.616   99.444  1.000 188.236 ? 570 GLU AAA OE2 1 ? 
HETATM 4196 PT PT  . PT  B 2 .   ? -0.543  3.871   72.286  0.500 75.460  ? 601 PT  AAA PT  1 ? 
HETATM 4197 PT PT  . PT  C 2 .   ? -41.543 -9.394  78.658  0.500 86.167  ? 602 PT  AAA PT  1 ? 
HETATM 4198 PT PT  . PT  D 2 .   ? -38.184 8.748   82.859  0.500 110.599 ? 603 PT  AAA PT  1 ? 
# 
