data_9HH2
# 
_entry.id   9HH2 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9HH2         pdb_00009hh2 10.2210/pdb9hh2/pdb 
WWPDB D_1292143210 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-04 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9HH2 
_pdbx_database_status.recvd_initial_deposition_date   2024-11-20 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              elizabeth.ficko.blean@sb-roscoff.fr 
_pdbx_contact_author.name_first         Elizabeth 
_pdbx_contact_author.name_last          Ficko-Blean 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0510-7929 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Chevenier, A.'   1 ? 
'Czjzek, M.'      2 ? 
'Michel, G.'      3 ? 
'Ficko-Blean, E.' 4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Carbohydr Polym' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1879-1344 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            358 
_citation.language                  ? 
_citation.page_first                123487 
_citation.page_last                 123487 
_citation.title                     
;Structure, function and catalytic mechanism of the carrageenan-sulfatases from the marine bacterium Zobellia galactanivorans Dsij T.
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.carbpol.2025.123487 
_citation.pdbx_database_id_PubMed   40383559 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Chevenier, A.'    1  ? 
primary 'Fanuel, M.'       2  ? 
primary 'Sokolova, E.'     3  ? 
primary 'Mico Latorre, D.' 4  ? 
primary 'Jouanneau, D.'    5  ? 
primary 'Jeudy, A.'        6  ? 
primary 'Prechoux, A.'     7  ? 
primary 'Zuhlke, M.K.'     8  ? 
primary 'Bartel, J.'       9  ? 
primary 'Becher, D.'       10 ? 
primary 'Czjzek, M.'       11 ? 
primary 'Ropartz, D.'      12 ? 
primary 'Michel, G.'       13 ? 
primary 'Ficko-Blean, E.'  14 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Sulfatase, family S1-19' 54778.480 2   3.1.6.- ? ? ? 
2 branched    man 
;3,6-anhydro-2-O-sulfo-alpha-D-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-3,6-anhydro-2-O-sulfo-alpha-D-galactopyranose-(1-3)-4-O-sulfo-beta-D-galactopyranose
;
870.737   2   ?       ? ? ? 
3 non-polymer syn 'CALCIUM ION' 40.078    2   ?       ? ? ? 
4 non-polymer syn 'BROMIDE ION' 79.904    6   ?       ? ? ? 
5 non-polymer syn 'CHLORIDE ION' 35.453    9   ?       ? ? ? 
6 non-polymer syn GLYCEROL 92.094    6   ?       ? ? ? 
7 water       nat water 18.015    997 ?       ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   yes 
_entity_poly.pdbx_seq_one_letter_code       
;MGSSHHHHHHGSQETRPNILVVLCDDLGYADVGFNGSTDILTPELDNLAQNGSIFTSAYVAHPF(OSE)GPSRSAILTGR
YPHLTGTAYNLFHNSSEDDKDNMGVPVEETYMSKVLQNAGYYTSAIGKWHLGAAPKFHPNKRGFDDFYGFLGGGHDYFPS
EYQKTYKAQKKAGNPNIRDYVFPMEHNGKPANETEYITDGFSREAIKNIKIAAAKKQPFFIYLAYNAPHVPLQAKAEDVA
KFAHIKDKDRRTYAAMVYAVDRGVGKIVQTLKETKQFDNTLIVFLSDNGGNFNHGANNYPLKGTKGDTWEGGYRVPMFFH
WPKKIKKDQRFDFPVSSLDLYPTFTGLAEAKLPKGKQLDGKNIMDDVLKNTEPYKDEMIYSLRYREGYNDVGARMGDWKI
TRMGNEPWRLHNITQDIGEKKNLAGRYPDRLKEMIAKTQEWTKSFVKPLWVYSVKDKELWESGQMPNYEATFEVDKLVDS
PYHK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGSSHHHHHHGSQETRPNILVVLCDDLGYADVGFNGSTDILTPELDNLAQNGSIFTSAYVAHPFSGPSRSAILTGRYPHL
TGTAYNLFHNSSEDDKDNMGVPVEETYMSKVLQNAGYYTSAIGKWHLGAAPKFHPNKRGFDDFYGFLGGGHDYFPSEYQK
TYKAQKKAGNPNIRDYVFPMEHNGKPANETEYITDGFSREAIKNIKIAAAKKQPFFIYLAYNAPHVPLQAKAEDVAKFAH
IKDKDRRTYAAMVYAVDRGVGKIVQTLKETKQFDNTLIVFLSDNGGNFNHGANNYPLKGTKGDTWEGGYRVPMFFHWPKK
IKKDQRFDFPVSSLDLYPTFTGLAEAKLPKGKQLDGKNIMDDVLKNTEPYKDEMIYSLRYREGYNDVGARMGDWKITRMG
NEPWRLHNITQDIGEKKNLAGRYPDRLKEMIAKTQEWTKSFVKPLWVYSVKDKELWESGQMPNYEATFEVDKLVDSPYHK
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 'CALCIUM ION'  CA  
4 'BROMIDE ION'  BR  
5 'CHLORIDE ION' CL  
6 GLYCEROL       GOL 
7 water          HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   SER n 
1 4   SER n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  GLY n 
1 12  SER n 
1 13  GLN n 
1 14  GLU n 
1 15  THR n 
1 16  ARG n 
1 17  PRO n 
1 18  ASN n 
1 19  ILE n 
1 20  LEU n 
1 21  VAL n 
1 22  VAL n 
1 23  LEU n 
1 24  CYS n 
1 25  ASP n 
1 26  ASP n 
1 27  LEU n 
1 28  GLY n 
1 29  TYR n 
1 30  ALA n 
1 31  ASP n 
1 32  VAL n 
1 33  GLY n 
1 34  PHE n 
1 35  ASN n 
1 36  GLY n 
1 37  SER n 
1 38  THR n 
1 39  ASP n 
1 40  ILE n 
1 41  LEU n 
1 42  THR n 
1 43  PRO n 
1 44  GLU n 
1 45  LEU n 
1 46  ASP n 
1 47  ASN n 
1 48  LEU n 
1 49  ALA n 
1 50  GLN n 
1 51  ASN n 
1 52  GLY n 
1 53  SER n 
1 54  ILE n 
1 55  PHE n 
1 56  THR n 
1 57  SER n 
1 58  ALA n 
1 59  TYR n 
1 60  VAL n 
1 61  ALA n 
1 62  HIS n 
1 63  PRO n 
1 64  PHE n 
1 65  OSE n 
1 66  GLY n 
1 67  PRO n 
1 68  SER n 
1 69  ARG n 
1 70  SER n 
1 71  ALA n 
1 72  ILE n 
1 73  LEU n 
1 74  THR n 
1 75  GLY n 
1 76  ARG n 
1 77  TYR n 
1 78  PRO n 
1 79  HIS n 
1 80  LEU n 
1 81  THR n 
1 82  GLY n 
1 83  THR n 
1 84  ALA n 
1 85  TYR n 
1 86  ASN n 
1 87  LEU n 
1 88  PHE n 
1 89  HIS n 
1 90  ASN n 
1 91  SER n 
1 92  SER n 
1 93  GLU n 
1 94  ASP n 
1 95  ASP n 
1 96  LYS n 
1 97  ASP n 
1 98  ASN n 
1 99  MET n 
1 100 GLY n 
1 101 VAL n 
1 102 PRO n 
1 103 VAL n 
1 104 GLU n 
1 105 GLU n 
1 106 THR n 
1 107 TYR n 
1 108 MET n 
1 109 SER n 
1 110 LYS n 
1 111 VAL n 
1 112 LEU n 
1 113 GLN n 
1 114 ASN n 
1 115 ALA n 
1 116 GLY n 
1 117 TYR n 
1 118 TYR n 
1 119 THR n 
1 120 SER n 
1 121 ALA n 
1 122 ILE n 
1 123 GLY n 
1 124 LYS n 
1 125 TRP n 
1 126 HIS n 
1 127 LEU n 
1 128 GLY n 
1 129 ALA n 
1 130 ALA n 
1 131 PRO n 
1 132 LYS n 
1 133 PHE n 
1 134 HIS n 
1 135 PRO n 
1 136 ASN n 
1 137 LYS n 
1 138 ARG n 
1 139 GLY n 
1 140 PHE n 
1 141 ASP n 
1 142 ASP n 
1 143 PHE n 
1 144 TYR n 
1 145 GLY n 
1 146 PHE n 
1 147 LEU n 
1 148 GLY n 
1 149 GLY n 
1 150 GLY n 
1 151 HIS n 
1 152 ASP n 
1 153 TYR n 
1 154 PHE n 
1 155 PRO n 
1 156 SER n 
1 157 GLU n 
1 158 TYR n 
1 159 GLN n 
1 160 LYS n 
1 161 THR n 
1 162 TYR n 
1 163 LYS n 
1 164 ALA n 
1 165 GLN n 
1 166 LYS n 
1 167 LYS n 
1 168 ALA n 
1 169 GLY n 
1 170 ASN n 
1 171 PRO n 
1 172 ASN n 
1 173 ILE n 
1 174 ARG n 
1 175 ASP n 
1 176 TYR n 
1 177 VAL n 
1 178 PHE n 
1 179 PRO n 
1 180 MET n 
1 181 GLU n 
1 182 HIS n 
1 183 ASN n 
1 184 GLY n 
1 185 LYS n 
1 186 PRO n 
1 187 ALA n 
1 188 ASN n 
1 189 GLU n 
1 190 THR n 
1 191 GLU n 
1 192 TYR n 
1 193 ILE n 
1 194 THR n 
1 195 ASP n 
1 196 GLY n 
1 197 PHE n 
1 198 SER n 
1 199 ARG n 
1 200 GLU n 
1 201 ALA n 
1 202 ILE n 
1 203 LYS n 
1 204 ASN n 
1 205 ILE n 
1 206 LYS n 
1 207 ILE n 
1 208 ALA n 
1 209 ALA n 
1 210 ALA n 
1 211 LYS n 
1 212 LYS n 
1 213 GLN n 
1 214 PRO n 
1 215 PHE n 
1 216 PHE n 
1 217 ILE n 
1 218 TYR n 
1 219 LEU n 
1 220 ALA n 
1 221 TYR n 
1 222 ASN n 
1 223 ALA n 
1 224 PRO n 
1 225 HIS n 
1 226 VAL n 
1 227 PRO n 
1 228 LEU n 
1 229 GLN n 
1 230 ALA n 
1 231 LYS n 
1 232 ALA n 
1 233 GLU n 
1 234 ASP n 
1 235 VAL n 
1 236 ALA n 
1 237 LYS n 
1 238 PHE n 
1 239 ALA n 
1 240 HIS n 
1 241 ILE n 
1 242 LYS n 
1 243 ASP n 
1 244 LYS n 
1 245 ASP n 
1 246 ARG n 
1 247 ARG n 
1 248 THR n 
1 249 TYR n 
1 250 ALA n 
1 251 ALA n 
1 252 MET n 
1 253 VAL n 
1 254 TYR n 
1 255 ALA n 
1 256 VAL n 
1 257 ASP n 
1 258 ARG n 
1 259 GLY n 
1 260 VAL n 
1 261 GLY n 
1 262 LYS n 
1 263 ILE n 
1 264 VAL n 
1 265 GLN n 
1 266 THR n 
1 267 LEU n 
1 268 LYS n 
1 269 GLU n 
1 270 THR n 
1 271 LYS n 
1 272 GLN n 
1 273 PHE n 
1 274 ASP n 
1 275 ASN n 
1 276 THR n 
1 277 LEU n 
1 278 ILE n 
1 279 VAL n 
1 280 PHE n 
1 281 LEU n 
1 282 SER n 
1 283 ASP n 
1 284 ASN n 
1 285 GLY n 
1 286 GLY n 
1 287 ASN n 
1 288 PHE n 
1 289 ASN n 
1 290 HIS n 
1 291 GLY n 
1 292 ALA n 
1 293 ASN n 
1 294 ASN n 
1 295 TYR n 
1 296 PRO n 
1 297 LEU n 
1 298 LYS n 
1 299 GLY n 
1 300 THR n 
1 301 LYS n 
1 302 GLY n 
1 303 ASP n 
1 304 THR n 
1 305 TRP n 
1 306 GLU n 
1 307 GLY n 
1 308 GLY n 
1 309 TYR n 
1 310 ARG n 
1 311 VAL n 
1 312 PRO n 
1 313 MET n 
1 314 PHE n 
1 315 PHE n 
1 316 HIS n 
1 317 TRP n 
1 318 PRO n 
1 319 LYS n 
1 320 LYS n 
1 321 ILE n 
1 322 LYS n 
1 323 LYS n 
1 324 ASP n 
1 325 GLN n 
1 326 ARG n 
1 327 PHE n 
1 328 ASP n 
1 329 PHE n 
1 330 PRO n 
1 331 VAL n 
1 332 SER n 
1 333 SER n 
1 334 LEU n 
1 335 ASP n 
1 336 LEU n 
1 337 TYR n 
1 338 PRO n 
1 339 THR n 
1 340 PHE n 
1 341 THR n 
1 342 GLY n 
1 343 LEU n 
1 344 ALA n 
1 345 GLU n 
1 346 ALA n 
1 347 LYS n 
1 348 LEU n 
1 349 PRO n 
1 350 LYS n 
1 351 GLY n 
1 352 LYS n 
1 353 GLN n 
1 354 LEU n 
1 355 ASP n 
1 356 GLY n 
1 357 LYS n 
1 358 ASN n 
1 359 ILE n 
1 360 MET n 
1 361 ASP n 
1 362 ASP n 
1 363 VAL n 
1 364 LEU n 
1 365 LYS n 
1 366 ASN n 
1 367 THR n 
1 368 GLU n 
1 369 PRO n 
1 370 TYR n 
1 371 LYS n 
1 372 ASP n 
1 373 GLU n 
1 374 MET n 
1 375 ILE n 
1 376 TYR n 
1 377 SER n 
1 378 LEU n 
1 379 ARG n 
1 380 TYR n 
1 381 ARG n 
1 382 GLU n 
1 383 GLY n 
1 384 TYR n 
1 385 ASN n 
1 386 ASP n 
1 387 VAL n 
1 388 GLY n 
1 389 ALA n 
1 390 ARG n 
1 391 MET n 
1 392 GLY n 
1 393 ASP n 
1 394 TRP n 
1 395 LYS n 
1 396 ILE n 
1 397 THR n 
1 398 ARG n 
1 399 MET n 
1 400 GLY n 
1 401 ASN n 
1 402 GLU n 
1 403 PRO n 
1 404 TRP n 
1 405 ARG n 
1 406 LEU n 
1 407 HIS n 
1 408 ASN n 
1 409 ILE n 
1 410 THR n 
1 411 GLN n 
1 412 ASP n 
1 413 ILE n 
1 414 GLY n 
1 415 GLU n 
1 416 LYS n 
1 417 LYS n 
1 418 ASN n 
1 419 LEU n 
1 420 ALA n 
1 421 GLY n 
1 422 ARG n 
1 423 TYR n 
1 424 PRO n 
1 425 ASP n 
1 426 ARG n 
1 427 LEU n 
1 428 LYS n 
1 429 GLU n 
1 430 MET n 
1 431 ILE n 
1 432 ALA n 
1 433 LYS n 
1 434 THR n 
1 435 GLN n 
1 436 GLU n 
1 437 TRP n 
1 438 THR n 
1 439 LYS n 
1 440 SER n 
1 441 PHE n 
1 442 VAL n 
1 443 LYS n 
1 444 PRO n 
1 445 LEU n 
1 446 TRP n 
1 447 VAL n 
1 448 TYR n 
1 449 SER n 
1 450 VAL n 
1 451 LYS n 
1 452 ASP n 
1 453 LYS n 
1 454 GLU n 
1 455 LEU n 
1 456 TRP n 
1 457 GLU n 
1 458 SER n 
1 459 GLY n 
1 460 GLN n 
1 461 MET n 
1 462 PRO n 
1 463 ASN n 
1 464 TYR n 
1 465 GLU n 
1 466 ALA n 
1 467 THR n 
1 468 PHE n 
1 469 GLU n 
1 470 VAL n 
1 471 ASP n 
1 472 LYS n 
1 473 LEU n 
1 474 VAL n 
1 475 ASP n 
1 476 SER n 
1 477 PRO n 
1 478 TYR n 
1 479 HIS n 
1 480 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   480 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 zobellia_3145 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Zobellia galactanivorans' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     63186 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_branch.entity_id   2 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 2 'WURCS=2.0/3,4,3/[a2112h-1b_1-5_4*OSO/3=O/3=O][a2112h-1a_1-5_3-6_2*OSO/3=O/3=O][a2112h-1b_1-5]/1-2-3-2/a3-b1_b4-c1_c3-d1' 
WURCS  PDB2Glycan 1.1.0 
2 2 '[][&lt;C12O15S2&gt;]{[(1+1)][b-D-Galp]{[(3+1)]{}}}'                                                                      
LINUCS PDB-CARE   ?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 2 2 DGS C1 O1 1 G4S O3 HO3 sing ? 
2 2 3 GAL C1 O1 2 DGS O4 HO4 sing ? 
3 2 4 DGS C1 O1 3 GAL O3 HO3 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE                                       ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                                      ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                                    ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                               ? 'C4 H7 N O4'     133.103 
BR  non-polymer                   . 'BROMIDE ION'                                 ? 'Br -1'          79.904  
CA  non-polymer                   . 'CALCIUM ION'                                 ? 'Ca 2'           40.078  
CL  non-polymer                   . 'CHLORIDE ION'                                ? 'Cl -1'          35.453  
CYS 'L-peptide linking'           y CYSTEINE                                      ? 'C3 H7 N O2 S'   121.158 
DGS 'D-saccharide, alpha linking' . 3,6-anhydro-2-O-sulfo-alpha-D-galactopyranose 
;3,6-ANHYDRO-D-GALACTOSE-2-SULFATE; 3,6-anhydro-2-O-sulfo-alpha-D-galactose; 3,6-anhydro-2-O-sulfo-D-galactose; 3,6-anhydro-2-O-sulfo-galactose
;
'C6 H10 O8 S'    242.204 
G4S 'D-saccharide, beta linking'  n 4-O-sulfo-beta-D-galactopyranose              
'4-O-sulfo-beta-D-galactose; 4-O-sulfo-D-galactose; 4-O-sulfo-galactose' 'C6 H12 O9 S'    260.219 
GAL 'D-saccharide, beta linking'  . beta-D-galactopyranose                        'beta-D-galactose; D-galactose; galactose' 
'C6 H12 O6'      180.156 
GLN 'L-peptide linking'           y GLUTAMINE                                     ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                               ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                                       ? 'C2 H5 N O2'     75.067  
GOL non-polymer                   . GLYCEROL                                      'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'       
92.094  
HIS 'L-peptide linking'           y HISTIDINE                                     ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer                   . WATER                                         ? 'H2 O'           18.015  
ILE 'L-peptide linking'           y ISOLEUCINE                                    ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                                       ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                                        ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'           y METHIONINE                                    ? 'C5 H11 N O2 S'  149.211 
OSE 'L-peptide linking'           n O-SULFO-L-SERINE                              ? 'C3 H7 N O6 S'   185.156 
PHE 'L-peptide linking'           y PHENYLALANINE                                 ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                                       ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                                        ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'           y THREONINE                                     ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                                    ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                                      ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                                        ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
G4S 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 'DGalp[4S]b'                
G4S 'COMMON NAME'                         GMML     1.0 4-sulfo-b-D-galactopyranose 
G4S 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Galp4SO3                
GAL 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGalpb                      
GAL 'COMMON NAME'                         GMML     1.0 b-D-galactopyranose         
GAL 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Galp                    
GAL 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Gal                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   32  ?   ?   ?   A . n 
A 1 2   GLY 2   33  ?   ?   ?   A . n 
A 1 3   SER 3   34  ?   ?   ?   A . n 
A 1 4   SER 4   35  ?   ?   ?   A . n 
A 1 5   HIS 5   36  ?   ?   ?   A . n 
A 1 6   HIS 6   37  ?   ?   ?   A . n 
A 1 7   HIS 7   38  ?   ?   ?   A . n 
A 1 8   HIS 8   39  ?   ?   ?   A . n 
A 1 9   HIS 9   40  ?   ?   ?   A . n 
A 1 10  HIS 10  41  ?   ?   ?   A . n 
A 1 11  GLY 11  42  ?   ?   ?   A . n 
A 1 12  SER 12  43  ?   ?   ?   A . n 
A 1 13  GLN 13  44  ?   ?   ?   A . n 
A 1 14  GLU 14  45  45  GLU GLU A . n 
A 1 15  THR 15  46  46  THR THR A . n 
A 1 16  ARG 16  47  47  ARG ARG A . n 
A 1 17  PRO 17  48  48  PRO PRO A . n 
A 1 18  ASN 18  49  49  ASN ASN A . n 
A 1 19  ILE 19  50  50  ILE ILE A . n 
A 1 20  LEU 20  51  51  LEU LEU A . n 
A 1 21  VAL 21  52  52  VAL VAL A . n 
A 1 22  VAL 22  53  53  VAL VAL A . n 
A 1 23  LEU 23  54  54  LEU LEU A . n 
A 1 24  CYS 24  55  55  CYS CYS A . n 
A 1 25  ASP 25  56  56  ASP ASP A . n 
A 1 26  ASP 26  57  57  ASP ASP A . n 
A 1 27  LEU 27  58  58  LEU LEU A . n 
A 1 28  GLY 28  59  59  GLY GLY A . n 
A 1 29  TYR 29  60  60  TYR TYR A . n 
A 1 30  ALA 30  61  61  ALA ALA A . n 
A 1 31  ASP 31  62  62  ASP ASP A . n 
A 1 32  VAL 32  63  63  VAL VAL A . n 
A 1 33  GLY 33  64  64  GLY GLY A . n 
A 1 34  PHE 34  65  65  PHE PHE A . n 
A 1 35  ASN 35  66  66  ASN ASN A . n 
A 1 36  GLY 36  67  67  GLY GLY A . n 
A 1 37  SER 37  68  68  SER SER A . n 
A 1 38  THR 38  69  69  THR THR A . n 
A 1 39  ASP 39  70  70  ASP ASP A . n 
A 1 40  ILE 40  71  71  ILE ILE A . n 
A 1 41  LEU 41  72  72  LEU LEU A . n 
A 1 42  THR 42  73  73  THR THR A . n 
A 1 43  PRO 43  74  74  PRO PRO A . n 
A 1 44  GLU 44  75  75  GLU GLU A . n 
A 1 45  LEU 45  76  76  LEU LEU A . n 
A 1 46  ASP 46  77  77  ASP ASP A . n 
A 1 47  ASN 47  78  78  ASN ASN A . n 
A 1 48  LEU 48  79  79  LEU LEU A . n 
A 1 49  ALA 49  80  80  ALA ALA A . n 
A 1 50  GLN 50  81  81  GLN GLN A . n 
A 1 51  ASN 51  82  82  ASN ASN A . n 
A 1 52  GLY 52  83  83  GLY GLY A . n 
A 1 53  SER 53  84  84  SER SER A . n 
A 1 54  ILE 54  85  85  ILE ILE A . n 
A 1 55  PHE 55  86  86  PHE PHE A . n 
A 1 56  THR 56  87  87  THR THR A . n 
A 1 57  SER 57  88  88  SER SER A . n 
A 1 58  ALA 58  89  89  ALA ALA A . n 
A 1 59  TYR 59  90  90  TYR TYR A . n 
A 1 60  VAL 60  91  91  VAL VAL A . n 
A 1 61  ALA 61  92  92  ALA ALA A . n 
A 1 62  HIS 62  93  93  HIS HIS A . n 
A 1 63  PRO 63  94  94  PRO PRO A . n 
A 1 64  PHE 64  95  95  PHE PHE A . n 
A 1 65  OSE 65  96  96  OSE OSE A . n 
A 1 66  GLY 66  97  97  GLY GLY A . n 
A 1 67  PRO 67  98  98  PRO PRO A . n 
A 1 68  SER 68  99  99  SER SER A . n 
A 1 69  ARG 69  100 100 ARG ARG A . n 
A 1 70  SER 70  101 101 SER SER A . n 
A 1 71  ALA 71  102 102 ALA ALA A . n 
A 1 72  ILE 72  103 103 ILE ILE A . n 
A 1 73  LEU 73  104 104 LEU LEU A . n 
A 1 74  THR 74  105 105 THR THR A . n 
A 1 75  GLY 75  106 106 GLY GLY A . n 
A 1 76  ARG 76  107 107 ARG ARG A . n 
A 1 77  TYR 77  108 108 TYR TYR A . n 
A 1 78  PRO 78  109 109 PRO PRO A . n 
A 1 79  HIS 79  110 110 HIS HIS A . n 
A 1 80  LEU 80  111 111 LEU LEU A . n 
A 1 81  THR 81  112 112 THR THR A . n 
A 1 82  GLY 82  113 113 GLY GLY A . n 
A 1 83  THR 83  114 114 THR THR A . n 
A 1 84  ALA 84  115 115 ALA ALA A . n 
A 1 85  TYR 85  116 116 TYR TYR A . n 
A 1 86  ASN 86  117 117 ASN ASN A . n 
A 1 87  LEU 87  118 118 LEU LEU A . n 
A 1 88  PHE 88  119 119 PHE PHE A . n 
A 1 89  HIS 89  120 120 HIS HIS A . n 
A 1 90  ASN 90  121 121 ASN ASN A . n 
A 1 91  SER 91  122 122 SER SER A . n 
A 1 92  SER 92  123 123 SER SER A . n 
A 1 93  GLU 93  124 124 GLU GLU A . n 
A 1 94  ASP 94  125 125 ASP ASP A . n 
A 1 95  ASP 95  126 126 ASP ASP A . n 
A 1 96  LYS 96  127 127 LYS LYS A . n 
A 1 97  ASP 97  128 128 ASP ASP A . n 
A 1 98  ASN 98  129 129 ASN ASN A . n 
A 1 99  MET 99  130 130 MET MET A . n 
A 1 100 GLY 100 131 131 GLY GLY A . n 
A 1 101 VAL 101 132 132 VAL VAL A . n 
A 1 102 PRO 102 133 133 PRO PRO A . n 
A 1 103 VAL 103 134 134 VAL VAL A . n 
A 1 104 GLU 104 135 135 GLU GLU A . n 
A 1 105 GLU 105 136 136 GLU GLU A . n 
A 1 106 THR 106 137 137 THR THR A . n 
A 1 107 TYR 107 138 138 TYR TYR A . n 
A 1 108 MET 108 139 139 MET MET A . n 
A 1 109 SER 109 140 140 SER SER A . n 
A 1 110 LYS 110 141 141 LYS LYS A . n 
A 1 111 VAL 111 142 142 VAL VAL A . n 
A 1 112 LEU 112 143 143 LEU LEU A . n 
A 1 113 GLN 113 144 144 GLN GLN A . n 
A 1 114 ASN 114 145 145 ASN ASN A . n 
A 1 115 ALA 115 146 146 ALA ALA A . n 
A 1 116 GLY 116 147 147 GLY GLY A . n 
A 1 117 TYR 117 148 148 TYR TYR A . n 
A 1 118 TYR 118 149 149 TYR TYR A . n 
A 1 119 THR 119 150 150 THR THR A . n 
A 1 120 SER 120 151 151 SER SER A . n 
A 1 121 ALA 121 152 152 ALA ALA A . n 
A 1 122 ILE 122 153 153 ILE ILE A . n 
A 1 123 GLY 123 154 154 GLY GLY A . n 
A 1 124 LYS 124 155 155 LYS LYS A . n 
A 1 125 TRP 125 156 156 TRP TRP A . n 
A 1 126 HIS 126 157 157 HIS HIS A . n 
A 1 127 LEU 127 158 158 LEU LEU A . n 
A 1 128 GLY 128 159 159 GLY GLY A . n 
A 1 129 ALA 129 160 160 ALA ALA A . n 
A 1 130 ALA 130 161 161 ALA ALA A . n 
A 1 131 PRO 131 162 162 PRO PRO A . n 
A 1 132 LYS 132 163 163 LYS LYS A . n 
A 1 133 PHE 133 164 164 PHE PHE A . n 
A 1 134 HIS 134 165 165 HIS HIS A . n 
A 1 135 PRO 135 166 166 PRO PRO A . n 
A 1 136 ASN 136 167 167 ASN ASN A . n 
A 1 137 LYS 137 168 168 LYS LYS A . n 
A 1 138 ARG 138 169 169 ARG ARG A . n 
A 1 139 GLY 139 170 170 GLY GLY A . n 
A 1 140 PHE 140 171 171 PHE PHE A . n 
A 1 141 ASP 141 172 172 ASP ASP A . n 
A 1 142 ASP 142 173 173 ASP ASP A . n 
A 1 143 PHE 143 174 174 PHE PHE A . n 
A 1 144 TYR 144 175 175 TYR TYR A . n 
A 1 145 GLY 145 176 176 GLY GLY A . n 
A 1 146 PHE 146 177 177 PHE PHE A . n 
A 1 147 LEU 147 178 178 LEU LEU A . n 
A 1 148 GLY 148 179 179 GLY GLY A . n 
A 1 149 GLY 149 180 180 GLY GLY A . n 
A 1 150 GLY 150 181 181 GLY GLY A . n 
A 1 151 HIS 151 182 182 HIS HIS A . n 
A 1 152 ASP 152 183 183 ASP ASP A . n 
A 1 153 TYR 153 184 184 TYR TYR A . n 
A 1 154 PHE 154 185 185 PHE PHE A . n 
A 1 155 PRO 155 186 186 PRO PRO A . n 
A 1 156 SER 156 187 187 SER SER A . n 
A 1 157 GLU 157 188 188 GLU GLU A . n 
A 1 158 TYR 158 189 189 TYR TYR A . n 
A 1 159 GLN 159 190 190 GLN GLN A . n 
A 1 160 LYS 160 191 191 LYS LYS A . n 
A 1 161 THR 161 192 192 THR THR A . n 
A 1 162 TYR 162 193 193 TYR TYR A . n 
A 1 163 LYS 163 194 194 LYS LYS A . n 
A 1 164 ALA 164 195 195 ALA ALA A . n 
A 1 165 GLN 165 196 196 GLN GLN A . n 
A 1 166 LYS 166 197 197 LYS LYS A . n 
A 1 167 LYS 167 198 198 LYS LYS A . n 
A 1 168 ALA 168 199 199 ALA ALA A . n 
A 1 169 GLY 169 200 200 GLY GLY A . n 
A 1 170 ASN 170 201 201 ASN ASN A . n 
A 1 171 PRO 171 202 202 PRO PRO A . n 
A 1 172 ASN 172 203 203 ASN ASN A . n 
A 1 173 ILE 173 204 204 ILE ILE A . n 
A 1 174 ARG 174 205 205 ARG ARG A . n 
A 1 175 ASP 175 206 206 ASP ASP A . n 
A 1 176 TYR 176 207 207 TYR TYR A . n 
A 1 177 VAL 177 208 208 VAL VAL A . n 
A 1 178 PHE 178 209 209 PHE PHE A . n 
A 1 179 PRO 179 210 210 PRO PRO A . n 
A 1 180 MET 180 211 211 MET MET A . n 
A 1 181 GLU 181 212 212 GLU GLU A . n 
A 1 182 HIS 182 213 213 HIS HIS A . n 
A 1 183 ASN 183 214 214 ASN ASN A . n 
A 1 184 GLY 184 215 215 GLY GLY A . n 
A 1 185 LYS 185 216 216 LYS LYS A . n 
A 1 186 PRO 186 217 217 PRO PRO A . n 
A 1 187 ALA 187 218 218 ALA ALA A . n 
A 1 188 ASN 188 219 219 ASN ASN A . n 
A 1 189 GLU 189 220 220 GLU GLU A . n 
A 1 190 THR 190 221 221 THR THR A . n 
A 1 191 GLU 191 222 222 GLU GLU A . n 
A 1 192 TYR 192 223 223 TYR TYR A . n 
A 1 193 ILE 193 224 224 ILE ILE A . n 
A 1 194 THR 194 225 225 THR THR A . n 
A 1 195 ASP 195 226 226 ASP ASP A . n 
A 1 196 GLY 196 227 227 GLY GLY A . n 
A 1 197 PHE 197 228 228 PHE PHE A . n 
A 1 198 SER 198 229 229 SER SER A . n 
A 1 199 ARG 199 230 230 ARG ARG A . n 
A 1 200 GLU 200 231 231 GLU GLU A . n 
A 1 201 ALA 201 232 232 ALA ALA A . n 
A 1 202 ILE 202 233 233 ILE ILE A . n 
A 1 203 LYS 203 234 234 LYS LYS A . n 
A 1 204 ASN 204 235 235 ASN ASN A . n 
A 1 205 ILE 205 236 236 ILE ILE A . n 
A 1 206 LYS 206 237 237 LYS LYS A . n 
A 1 207 ILE 207 238 238 ILE ILE A . n 
A 1 208 ALA 208 239 239 ALA ALA A . n 
A 1 209 ALA 209 240 240 ALA ALA A . n 
A 1 210 ALA 210 241 241 ALA ALA A . n 
A 1 211 LYS 211 242 242 LYS LYS A . n 
A 1 212 LYS 212 243 243 LYS LYS A . n 
A 1 213 GLN 213 244 244 GLN GLN A . n 
A 1 214 PRO 214 245 245 PRO PRO A . n 
A 1 215 PHE 215 246 246 PHE PHE A . n 
A 1 216 PHE 216 247 247 PHE PHE A . n 
A 1 217 ILE 217 248 248 ILE ILE A . n 
A 1 218 TYR 218 249 249 TYR TYR A . n 
A 1 219 LEU 219 250 250 LEU LEU A . n 
A 1 220 ALA 220 251 251 ALA ALA A . n 
A 1 221 TYR 221 252 252 TYR TYR A . n 
A 1 222 ASN 222 253 253 ASN ASN A . n 
A 1 223 ALA 223 254 254 ALA ALA A . n 
A 1 224 PRO 224 255 255 PRO PRO A . n 
A 1 225 HIS 225 256 256 HIS HIS A . n 
A 1 226 VAL 226 257 257 VAL VAL A . n 
A 1 227 PRO 227 258 258 PRO PRO A . n 
A 1 228 LEU 228 259 259 LEU LEU A . n 
A 1 229 GLN 229 260 260 GLN GLN A . n 
A 1 230 ALA 230 261 261 ALA ALA A . n 
A 1 231 LYS 231 262 262 LYS LYS A . n 
A 1 232 ALA 232 263 263 ALA ALA A . n 
A 1 233 GLU 233 264 264 GLU GLU A . n 
A 1 234 ASP 234 265 265 ASP ASP A . n 
A 1 235 VAL 235 266 266 VAL VAL A . n 
A 1 236 ALA 236 267 267 ALA ALA A . n 
A 1 237 LYS 237 268 268 LYS LYS A . n 
A 1 238 PHE 238 269 269 PHE PHE A . n 
A 1 239 ALA 239 270 270 ALA ALA A . n 
A 1 240 HIS 240 271 271 HIS HIS A . n 
A 1 241 ILE 241 272 272 ILE ILE A . n 
A 1 242 LYS 242 273 273 LYS LYS A . n 
A 1 243 ASP 243 274 274 ASP ASP A . n 
A 1 244 LYS 244 275 275 LYS LYS A . n 
A 1 245 ASP 245 276 276 ASP ASP A . n 
A 1 246 ARG 246 277 277 ARG ARG A . n 
A 1 247 ARG 247 278 278 ARG ARG A . n 
A 1 248 THR 248 279 279 THR THR A . n 
A 1 249 TYR 249 280 280 TYR TYR A . n 
A 1 250 ALA 250 281 281 ALA ALA A . n 
A 1 251 ALA 251 282 282 ALA ALA A . n 
A 1 252 MET 252 283 283 MET MET A . n 
A 1 253 VAL 253 284 284 VAL VAL A . n 
A 1 254 TYR 254 285 285 TYR TYR A . n 
A 1 255 ALA 255 286 286 ALA ALA A . n 
A 1 256 VAL 256 287 287 VAL VAL A . n 
A 1 257 ASP 257 288 288 ASP ASP A . n 
A 1 258 ARG 258 289 289 ARG ARG A . n 
A 1 259 GLY 259 290 290 GLY GLY A . n 
A 1 260 VAL 260 291 291 VAL VAL A . n 
A 1 261 GLY 261 292 292 GLY GLY A . n 
A 1 262 LYS 262 293 293 LYS LYS A . n 
A 1 263 ILE 263 294 294 ILE ILE A . n 
A 1 264 VAL 264 295 295 VAL VAL A . n 
A 1 265 GLN 265 296 296 GLN GLN A . n 
A 1 266 THR 266 297 297 THR THR A . n 
A 1 267 LEU 267 298 298 LEU LEU A . n 
A 1 268 LYS 268 299 299 LYS LYS A . n 
A 1 269 GLU 269 300 300 GLU GLU A . n 
A 1 270 THR 270 301 301 THR THR A . n 
A 1 271 LYS 271 302 302 LYS LYS A . n 
A 1 272 GLN 272 303 303 GLN GLN A . n 
A 1 273 PHE 273 304 304 PHE PHE A . n 
A 1 274 ASP 274 305 305 ASP ASP A . n 
A 1 275 ASN 275 306 306 ASN ASN A . n 
A 1 276 THR 276 307 307 THR THR A . n 
A 1 277 LEU 277 308 308 LEU LEU A . n 
A 1 278 ILE 278 309 309 ILE ILE A . n 
A 1 279 VAL 279 310 310 VAL VAL A . n 
A 1 280 PHE 280 311 311 PHE PHE A . n 
A 1 281 LEU 281 312 312 LEU LEU A . n 
A 1 282 SER 282 313 313 SER SER A . n 
A 1 283 ASP 283 314 314 ASP ASP A . n 
A 1 284 ASN 284 315 315 ASN ASN A . n 
A 1 285 GLY 285 316 316 GLY GLY A . n 
A 1 286 GLY 286 317 317 GLY GLY A . n 
A 1 287 ASN 287 318 318 ASN ASN A . n 
A 1 288 PHE 288 319 319 PHE PHE A . n 
A 1 289 ASN 289 320 320 ASN ASN A . n 
A 1 290 HIS 290 321 321 HIS HIS A . n 
A 1 291 GLY 291 322 322 GLY GLY A . n 
A 1 292 ALA 292 323 323 ALA ALA A . n 
A 1 293 ASN 293 324 324 ASN ASN A . n 
A 1 294 ASN 294 325 325 ASN ASN A . n 
A 1 295 TYR 295 326 326 TYR TYR A . n 
A 1 296 PRO 296 327 327 PRO PRO A . n 
A 1 297 LEU 297 328 328 LEU LEU A . n 
A 1 298 LYS 298 329 329 LYS LYS A . n 
A 1 299 GLY 299 330 330 GLY GLY A . n 
A 1 300 THR 300 331 331 THR THR A . n 
A 1 301 LYS 301 332 332 LYS LYS A . n 
A 1 302 GLY 302 333 333 GLY GLY A . n 
A 1 303 ASP 303 334 334 ASP ASP A . n 
A 1 304 THR 304 335 335 THR THR A . n 
A 1 305 TRP 305 336 336 TRP TRP A . n 
A 1 306 GLU 306 337 337 GLU GLU A . n 
A 1 307 GLY 307 338 338 GLY GLY A . n 
A 1 308 GLY 308 339 339 GLY GLY A . n 
A 1 309 TYR 309 340 340 TYR TYR A . n 
A 1 310 ARG 310 341 341 ARG ARG A . n 
A 1 311 VAL 311 342 342 VAL VAL A . n 
A 1 312 PRO 312 343 343 PRO PRO A . n 
A 1 313 MET 313 344 344 MET MET A . n 
A 1 314 PHE 314 345 345 PHE PHE A . n 
A 1 315 PHE 315 346 346 PHE PHE A . n 
A 1 316 HIS 316 347 347 HIS HIS A . n 
A 1 317 TRP 317 348 348 TRP TRP A . n 
A 1 318 PRO 318 349 349 PRO PRO A . n 
A 1 319 LYS 319 350 350 LYS LYS A . n 
A 1 320 LYS 320 351 351 LYS LYS A . n 
A 1 321 ILE 321 352 352 ILE ILE A . n 
A 1 322 LYS 322 353 353 LYS LYS A . n 
A 1 323 LYS 323 354 354 LYS LYS A . n 
A 1 324 ASP 324 355 355 ASP ASP A . n 
A 1 325 GLN 325 356 356 GLN GLN A . n 
A 1 326 ARG 326 357 357 ARG ARG A . n 
A 1 327 PHE 327 358 358 PHE PHE A . n 
A 1 328 ASP 328 359 359 ASP ASP A . n 
A 1 329 PHE 329 360 360 PHE PHE A . n 
A 1 330 PRO 330 361 361 PRO PRO A . n 
A 1 331 VAL 331 362 362 VAL VAL A . n 
A 1 332 SER 332 363 363 SER SER A . n 
A 1 333 SER 333 364 364 SER SER A . n 
A 1 334 LEU 334 365 365 LEU LEU A . n 
A 1 335 ASP 335 366 366 ASP ASP A . n 
A 1 336 LEU 336 367 367 LEU LEU A . n 
A 1 337 TYR 337 368 368 TYR TYR A . n 
A 1 338 PRO 338 369 369 PRO PRO A . n 
A 1 339 THR 339 370 370 THR THR A . n 
A 1 340 PHE 340 371 371 PHE PHE A . n 
A 1 341 THR 341 372 372 THR THR A . n 
A 1 342 GLY 342 373 373 GLY GLY A . n 
A 1 343 LEU 343 374 374 LEU LEU A . n 
A 1 344 ALA 344 375 375 ALA ALA A . n 
A 1 345 GLU 345 376 376 GLU GLU A . n 
A 1 346 ALA 346 377 377 ALA ALA A . n 
A 1 347 LYS 347 378 378 LYS LYS A . n 
A 1 348 LEU 348 379 379 LEU LEU A . n 
A 1 349 PRO 349 380 380 PRO PRO A . n 
A 1 350 LYS 350 381 381 LYS LYS A . n 
A 1 351 GLY 351 382 382 GLY GLY A . n 
A 1 352 LYS 352 383 383 LYS LYS A . n 
A 1 353 GLN 353 384 384 GLN GLN A . n 
A 1 354 LEU 354 385 385 LEU LEU A . n 
A 1 355 ASP 355 386 386 ASP ASP A . n 
A 1 356 GLY 356 387 387 GLY GLY A . n 
A 1 357 LYS 357 388 388 LYS LYS A . n 
A 1 358 ASN 358 389 389 ASN ASN A . n 
A 1 359 ILE 359 390 390 ILE ILE A . n 
A 1 360 MET 360 391 391 MET MET A . n 
A 1 361 ASP 361 392 392 ASP ASP A . n 
A 1 362 ASP 362 393 393 ASP ASP A . n 
A 1 363 VAL 363 394 394 VAL VAL A . n 
A 1 364 LEU 364 395 395 LEU LEU A . n 
A 1 365 LYS 365 396 396 LYS LYS A . n 
A 1 366 ASN 366 397 397 ASN ASN A . n 
A 1 367 THR 367 398 398 THR THR A . n 
A 1 368 GLU 368 399 399 GLU GLU A . n 
A 1 369 PRO 369 400 400 PRO PRO A . n 
A 1 370 TYR 370 401 401 TYR TYR A . n 
A 1 371 LYS 371 402 402 LYS LYS A . n 
A 1 372 ASP 372 403 403 ASP ASP A . n 
A 1 373 GLU 373 404 404 GLU GLU A . n 
A 1 374 MET 374 405 405 MET MET A . n 
A 1 375 ILE 375 406 406 ILE ILE A . n 
A 1 376 TYR 376 407 407 TYR TYR A . n 
A 1 377 SER 377 408 408 SER SER A . n 
A 1 378 LEU 378 409 409 LEU LEU A . n 
A 1 379 ARG 379 410 410 ARG ARG A . n 
A 1 380 TYR 380 411 411 TYR TYR A . n 
A 1 381 ARG 381 412 412 ARG ARG A . n 
A 1 382 GLU 382 413 413 GLU GLU A . n 
A 1 383 GLY 383 414 414 GLY GLY A . n 
A 1 384 TYR 384 415 415 TYR TYR A . n 
A 1 385 ASN 385 416 416 ASN ASN A . n 
A 1 386 ASP 386 417 417 ASP ASP A . n 
A 1 387 VAL 387 418 418 VAL VAL A . n 
A 1 388 GLY 388 419 419 GLY GLY A . n 
A 1 389 ALA 389 420 420 ALA ALA A . n 
A 1 390 ARG 390 421 421 ARG ARG A . n 
A 1 391 MET 391 422 422 MET MET A . n 
A 1 392 GLY 392 423 423 GLY GLY A . n 
A 1 393 ASP 393 424 424 ASP ASP A . n 
A 1 394 TRP 394 425 425 TRP TRP A . n 
A 1 395 LYS 395 426 426 LYS LYS A . n 
A 1 396 ILE 396 427 427 ILE ILE A . n 
A 1 397 THR 397 428 428 THR THR A . n 
A 1 398 ARG 398 429 429 ARG ARG A . n 
A 1 399 MET 399 430 430 MET MET A . n 
A 1 400 GLY 400 431 431 GLY GLY A . n 
A 1 401 ASN 401 432 432 ASN ASN A . n 
A 1 402 GLU 402 433 433 GLU GLU A . n 
A 1 403 PRO 403 434 434 PRO PRO A . n 
A 1 404 TRP 404 435 435 TRP TRP A . n 
A 1 405 ARG 405 436 436 ARG ARG A . n 
A 1 406 LEU 406 437 437 LEU LEU A . n 
A 1 407 HIS 407 438 438 HIS HIS A . n 
A 1 408 ASN 408 439 439 ASN ASN A . n 
A 1 409 ILE 409 440 440 ILE ILE A . n 
A 1 410 THR 410 441 441 THR THR A . n 
A 1 411 GLN 411 442 442 GLN GLN A . n 
A 1 412 ASP 412 443 443 ASP ASP A . n 
A 1 413 ILE 413 444 444 ILE ILE A . n 
A 1 414 GLY 414 445 445 GLY GLY A . n 
A 1 415 GLU 415 446 446 GLU GLU A . n 
A 1 416 LYS 416 447 447 LYS LYS A . n 
A 1 417 LYS 417 448 448 LYS LYS A . n 
A 1 418 ASN 418 449 449 ASN ASN A . n 
A 1 419 LEU 419 450 450 LEU LEU A . n 
A 1 420 ALA 420 451 451 ALA ALA A . n 
A 1 421 GLY 421 452 452 GLY GLY A . n 
A 1 422 ARG 422 453 453 ARG ARG A . n 
A 1 423 TYR 423 454 454 TYR TYR A . n 
A 1 424 PRO 424 455 455 PRO PRO A . n 
A 1 425 ASP 425 456 456 ASP ASP A . n 
A 1 426 ARG 426 457 457 ARG ARG A . n 
A 1 427 LEU 427 458 458 LEU LEU A . n 
A 1 428 LYS 428 459 459 LYS LYS A . n 
A 1 429 GLU 429 460 460 GLU GLU A . n 
A 1 430 MET 430 461 461 MET MET A . n 
A 1 431 ILE 431 462 462 ILE ILE A . n 
A 1 432 ALA 432 463 463 ALA ALA A . n 
A 1 433 LYS 433 464 464 LYS LYS A . n 
A 1 434 THR 434 465 465 THR THR A . n 
A 1 435 GLN 435 466 466 GLN GLN A . n 
A 1 436 GLU 436 467 467 GLU GLU A . n 
A 1 437 TRP 437 468 468 TRP TRP A . n 
A 1 438 THR 438 469 469 THR THR A . n 
A 1 439 LYS 439 470 470 LYS LYS A . n 
A 1 440 SER 440 471 471 SER SER A . n 
A 1 441 PHE 441 472 472 PHE PHE A . n 
A 1 442 VAL 442 473 473 VAL VAL A . n 
A 1 443 LYS 443 474 474 LYS LYS A . n 
A 1 444 PRO 444 475 475 PRO PRO A . n 
A 1 445 LEU 445 476 476 LEU LEU A . n 
A 1 446 TRP 446 477 477 TRP TRP A . n 
A 1 447 VAL 447 478 478 VAL VAL A . n 
A 1 448 TYR 448 479 479 TYR TYR A . n 
A 1 449 SER 449 480 480 SER SER A . n 
A 1 450 VAL 450 481 481 VAL VAL A . n 
A 1 451 LYS 451 482 482 LYS LYS A . n 
A 1 452 ASP 452 483 483 ASP ASP A . n 
A 1 453 LYS 453 484 484 LYS LYS A . n 
A 1 454 GLU 454 485 485 GLU GLU A . n 
A 1 455 LEU 455 486 486 LEU LEU A . n 
A 1 456 TRP 456 487 487 TRP TRP A . n 
A 1 457 GLU 457 488 488 GLU GLU A . n 
A 1 458 SER 458 489 489 SER SER A . n 
A 1 459 GLY 459 490 490 GLY GLY A . n 
A 1 460 GLN 460 491 491 GLN GLN A . n 
A 1 461 MET 461 492 492 MET MET A . n 
A 1 462 PRO 462 493 493 PRO PRO A . n 
A 1 463 ASN 463 494 494 ASN ASN A . n 
A 1 464 TYR 464 495 495 TYR TYR A . n 
A 1 465 GLU 465 496 496 GLU GLU A . n 
A 1 466 ALA 466 497 497 ALA ALA A . n 
A 1 467 THR 467 498 498 THR THR A . n 
A 1 468 PHE 468 499 499 PHE PHE A . n 
A 1 469 GLU 469 500 500 GLU GLU A . n 
A 1 470 VAL 470 501 501 VAL VAL A . n 
A 1 471 ASP 471 502 502 ASP ASP A . n 
A 1 472 LYS 472 503 503 LYS LYS A . n 
A 1 473 LEU 473 504 504 LEU LEU A . n 
A 1 474 VAL 474 505 505 VAL VAL A . n 
A 1 475 ASP 475 506 506 ASP ASP A . n 
A 1 476 SER 476 507 507 SER SER A . n 
A 1 477 PRO 477 508 508 PRO PRO A . n 
A 1 478 TYR 478 509 509 TYR TYR A . n 
A 1 479 HIS 479 510 510 HIS HIS A . n 
A 1 480 LYS 480 511 ?   ?   ?   A . n 
B 1 1   MET 1   32  ?   ?   ?   B . n 
B 1 2   GLY 2   33  ?   ?   ?   B . n 
B 1 3   SER 3   34  ?   ?   ?   B . n 
B 1 4   SER 4   35  ?   ?   ?   B . n 
B 1 5   HIS 5   36  ?   ?   ?   B . n 
B 1 6   HIS 6   37  ?   ?   ?   B . n 
B 1 7   HIS 7   38  ?   ?   ?   B . n 
B 1 8   HIS 8   39  ?   ?   ?   B . n 
B 1 9   HIS 9   40  ?   ?   ?   B . n 
B 1 10  HIS 10  41  ?   ?   ?   B . n 
B 1 11  GLY 11  42  ?   ?   ?   B . n 
B 1 12  SER 12  43  ?   ?   ?   B . n 
B 1 13  GLN 13  44  ?   ?   ?   B . n 
B 1 14  GLU 14  45  45  GLU GLU B . n 
B 1 15  THR 15  46  46  THR THR B . n 
B 1 16  ARG 16  47  47  ARG ARG B . n 
B 1 17  PRO 17  48  48  PRO PRO B . n 
B 1 18  ASN 18  49  49  ASN ASN B . n 
B 1 19  ILE 19  50  50  ILE ILE B . n 
B 1 20  LEU 20  51  51  LEU LEU B . n 
B 1 21  VAL 21  52  52  VAL VAL B . n 
B 1 22  VAL 22  53  53  VAL VAL B . n 
B 1 23  LEU 23  54  54  LEU LEU B . n 
B 1 24  CYS 24  55  55  CYS CYS B . n 
B 1 25  ASP 25  56  56  ASP ASP B . n 
B 1 26  ASP 26  57  57  ASP ASP B . n 
B 1 27  LEU 27  58  58  LEU LEU B . n 
B 1 28  GLY 28  59  59  GLY GLY B . n 
B 1 29  TYR 29  60  60  TYR TYR B . n 
B 1 30  ALA 30  61  61  ALA ALA B . n 
B 1 31  ASP 31  62  62  ASP ASP B . n 
B 1 32  VAL 32  63  63  VAL VAL B . n 
B 1 33  GLY 33  64  64  GLY GLY B . n 
B 1 34  PHE 34  65  65  PHE PHE B . n 
B 1 35  ASN 35  66  66  ASN ASN B . n 
B 1 36  GLY 36  67  67  GLY GLY B . n 
B 1 37  SER 37  68  68  SER SER B . n 
B 1 38  THR 38  69  69  THR THR B . n 
B 1 39  ASP 39  70  70  ASP ASP B . n 
B 1 40  ILE 40  71  71  ILE ILE B . n 
B 1 41  LEU 41  72  72  LEU LEU B . n 
B 1 42  THR 42  73  73  THR THR B . n 
B 1 43  PRO 43  74  74  PRO PRO B . n 
B 1 44  GLU 44  75  75  GLU GLU B . n 
B 1 45  LEU 45  76  76  LEU LEU B . n 
B 1 46  ASP 46  77  77  ASP ASP B . n 
B 1 47  ASN 47  78  78  ASN ASN B . n 
B 1 48  LEU 48  79  79  LEU LEU B . n 
B 1 49  ALA 49  80  80  ALA ALA B . n 
B 1 50  GLN 50  81  81  GLN GLN B . n 
B 1 51  ASN 51  82  82  ASN ASN B . n 
B 1 52  GLY 52  83  83  GLY GLY B . n 
B 1 53  SER 53  84  84  SER SER B . n 
B 1 54  ILE 54  85  85  ILE ILE B . n 
B 1 55  PHE 55  86  86  PHE PHE B . n 
B 1 56  THR 56  87  87  THR THR B . n 
B 1 57  SER 57  88  88  SER SER B . n 
B 1 58  ALA 58  89  89  ALA ALA B . n 
B 1 59  TYR 59  90  90  TYR TYR B . n 
B 1 60  VAL 60  91  91  VAL VAL B . n 
B 1 61  ALA 61  92  92  ALA ALA B . n 
B 1 62  HIS 62  93  93  HIS HIS B . n 
B 1 63  PRO 63  94  94  PRO PRO B . n 
B 1 64  PHE 64  95  95  PHE PHE B . n 
B 1 65  OSE 65  96  96  OSE OSE B . n 
B 1 66  GLY 66  97  97  GLY GLY B . n 
B 1 67  PRO 67  98  98  PRO PRO B . n 
B 1 68  SER 68  99  99  SER SER B . n 
B 1 69  ARG 69  100 100 ARG ARG B . n 
B 1 70  SER 70  101 101 SER SER B . n 
B 1 71  ALA 71  102 102 ALA ALA B . n 
B 1 72  ILE 72  103 103 ILE ILE B . n 
B 1 73  LEU 73  104 104 LEU LEU B . n 
B 1 74  THR 74  105 105 THR THR B . n 
B 1 75  GLY 75  106 106 GLY GLY B . n 
B 1 76  ARG 76  107 107 ARG ARG B . n 
B 1 77  TYR 77  108 108 TYR TYR B . n 
B 1 78  PRO 78  109 109 PRO PRO B . n 
B 1 79  HIS 79  110 110 HIS HIS B . n 
B 1 80  LEU 80  111 111 LEU LEU B . n 
B 1 81  THR 81  112 112 THR THR B . n 
B 1 82  GLY 82  113 113 GLY GLY B . n 
B 1 83  THR 83  114 114 THR THR B . n 
B 1 84  ALA 84  115 115 ALA ALA B . n 
B 1 85  TYR 85  116 116 TYR TYR B . n 
B 1 86  ASN 86  117 117 ASN ASN B . n 
B 1 87  LEU 87  118 118 LEU LEU B . n 
B 1 88  PHE 88  119 119 PHE PHE B . n 
B 1 89  HIS 89  120 120 HIS HIS B . n 
B 1 90  ASN 90  121 121 ASN ASN B . n 
B 1 91  SER 91  122 122 SER SER B . n 
B 1 92  SER 92  123 123 SER SER B . n 
B 1 93  GLU 93  124 124 GLU GLU B . n 
B 1 94  ASP 94  125 125 ASP ASP B . n 
B 1 95  ASP 95  126 126 ASP ASP B . n 
B 1 96  LYS 96  127 127 LYS LYS B . n 
B 1 97  ASP 97  128 128 ASP ASP B . n 
B 1 98  ASN 98  129 129 ASN ASN B . n 
B 1 99  MET 99  130 130 MET MET B . n 
B 1 100 GLY 100 131 131 GLY GLY B . n 
B 1 101 VAL 101 132 132 VAL VAL B . n 
B 1 102 PRO 102 133 133 PRO PRO B . n 
B 1 103 VAL 103 134 134 VAL VAL B . n 
B 1 104 GLU 104 135 135 GLU GLU B . n 
B 1 105 GLU 105 136 136 GLU GLU B . n 
B 1 106 THR 106 137 137 THR THR B . n 
B 1 107 TYR 107 138 138 TYR TYR B . n 
B 1 108 MET 108 139 139 MET MET B . n 
B 1 109 SER 109 140 140 SER SER B . n 
B 1 110 LYS 110 141 141 LYS LYS B . n 
B 1 111 VAL 111 142 142 VAL VAL B . n 
B 1 112 LEU 112 143 143 LEU LEU B . n 
B 1 113 GLN 113 144 144 GLN GLN B . n 
B 1 114 ASN 114 145 145 ASN ASN B . n 
B 1 115 ALA 115 146 146 ALA ALA B . n 
B 1 116 GLY 116 147 147 GLY GLY B . n 
B 1 117 TYR 117 148 148 TYR TYR B . n 
B 1 118 TYR 118 149 149 TYR TYR B . n 
B 1 119 THR 119 150 150 THR THR B . n 
B 1 120 SER 120 151 151 SER SER B . n 
B 1 121 ALA 121 152 152 ALA ALA B . n 
B 1 122 ILE 122 153 153 ILE ILE B . n 
B 1 123 GLY 123 154 154 GLY GLY B . n 
B 1 124 LYS 124 155 155 LYS LYS B . n 
B 1 125 TRP 125 156 156 TRP TRP B . n 
B 1 126 HIS 126 157 157 HIS HIS B . n 
B 1 127 LEU 127 158 158 LEU LEU B . n 
B 1 128 GLY 128 159 159 GLY GLY B . n 
B 1 129 ALA 129 160 160 ALA ALA B . n 
B 1 130 ALA 130 161 161 ALA ALA B . n 
B 1 131 PRO 131 162 162 PRO PRO B . n 
B 1 132 LYS 132 163 163 LYS LYS B . n 
B 1 133 PHE 133 164 164 PHE PHE B . n 
B 1 134 HIS 134 165 165 HIS HIS B . n 
B 1 135 PRO 135 166 166 PRO PRO B . n 
B 1 136 ASN 136 167 167 ASN ASN B . n 
B 1 137 LYS 137 168 168 LYS LYS B . n 
B 1 138 ARG 138 169 169 ARG ARG B . n 
B 1 139 GLY 139 170 170 GLY GLY B . n 
B 1 140 PHE 140 171 171 PHE PHE B . n 
B 1 141 ASP 141 172 172 ASP ASP B . n 
B 1 142 ASP 142 173 173 ASP ASP B . n 
B 1 143 PHE 143 174 174 PHE PHE B . n 
B 1 144 TYR 144 175 175 TYR TYR B . n 
B 1 145 GLY 145 176 176 GLY GLY B . n 
B 1 146 PHE 146 177 177 PHE PHE B . n 
B 1 147 LEU 147 178 178 LEU LEU B . n 
B 1 148 GLY 148 179 179 GLY GLY B . n 
B 1 149 GLY 149 180 180 GLY GLY B . n 
B 1 150 GLY 150 181 181 GLY GLY B . n 
B 1 151 HIS 151 182 182 HIS HIS B . n 
B 1 152 ASP 152 183 183 ASP ASP B . n 
B 1 153 TYR 153 184 184 TYR TYR B . n 
B 1 154 PHE 154 185 185 PHE PHE B . n 
B 1 155 PRO 155 186 186 PRO PRO B . n 
B 1 156 SER 156 187 187 SER SER B . n 
B 1 157 GLU 157 188 188 GLU GLU B . n 
B 1 158 TYR 158 189 189 TYR TYR B . n 
B 1 159 GLN 159 190 190 GLN GLN B . n 
B 1 160 LYS 160 191 191 LYS LYS B . n 
B 1 161 THR 161 192 192 THR THR B . n 
B 1 162 TYR 162 193 193 TYR TYR B . n 
B 1 163 LYS 163 194 194 LYS LYS B . n 
B 1 164 ALA 164 195 195 ALA ALA B . n 
B 1 165 GLN 165 196 196 GLN GLN B . n 
B 1 166 LYS 166 197 197 LYS LYS B . n 
B 1 167 LYS 167 198 198 LYS LYS B . n 
B 1 168 ALA 168 199 199 ALA ALA B . n 
B 1 169 GLY 169 200 200 GLY GLY B . n 
B 1 170 ASN 170 201 201 ASN ASN B . n 
B 1 171 PRO 171 202 202 PRO PRO B . n 
B 1 172 ASN 172 203 203 ASN ASN B . n 
B 1 173 ILE 173 204 204 ILE ILE B . n 
B 1 174 ARG 174 205 205 ARG ARG B . n 
B 1 175 ASP 175 206 206 ASP ASP B . n 
B 1 176 TYR 176 207 207 TYR TYR B . n 
B 1 177 VAL 177 208 208 VAL VAL B . n 
B 1 178 PHE 178 209 209 PHE PHE B . n 
B 1 179 PRO 179 210 210 PRO PRO B . n 
B 1 180 MET 180 211 211 MET MET B . n 
B 1 181 GLU 181 212 212 GLU GLU B . n 
B 1 182 HIS 182 213 213 HIS HIS B . n 
B 1 183 ASN 183 214 214 ASN ASN B . n 
B 1 184 GLY 184 215 215 GLY GLY B . n 
B 1 185 LYS 185 216 216 LYS LYS B . n 
B 1 186 PRO 186 217 217 PRO PRO B . n 
B 1 187 ALA 187 218 218 ALA ALA B . n 
B 1 188 ASN 188 219 219 ASN ASN B . n 
B 1 189 GLU 189 220 220 GLU GLU B . n 
B 1 190 THR 190 221 221 THR THR B . n 
B 1 191 GLU 191 222 222 GLU GLU B . n 
B 1 192 TYR 192 223 223 TYR TYR B . n 
B 1 193 ILE 193 224 224 ILE ILE B . n 
B 1 194 THR 194 225 225 THR THR B . n 
B 1 195 ASP 195 226 226 ASP ASP B . n 
B 1 196 GLY 196 227 227 GLY GLY B . n 
B 1 197 PHE 197 228 228 PHE PHE B . n 
B 1 198 SER 198 229 229 SER SER B . n 
B 1 199 ARG 199 230 230 ARG ARG B . n 
B 1 200 GLU 200 231 231 GLU GLU B . n 
B 1 201 ALA 201 232 232 ALA ALA B . n 
B 1 202 ILE 202 233 233 ILE ILE B . n 
B 1 203 LYS 203 234 234 LYS LYS B . n 
B 1 204 ASN 204 235 235 ASN ASN B . n 
B 1 205 ILE 205 236 236 ILE ILE B . n 
B 1 206 LYS 206 237 237 LYS LYS B . n 
B 1 207 ILE 207 238 238 ILE ILE B . n 
B 1 208 ALA 208 239 239 ALA ALA B . n 
B 1 209 ALA 209 240 240 ALA ALA B . n 
B 1 210 ALA 210 241 241 ALA ALA B . n 
B 1 211 LYS 211 242 242 LYS LYS B . n 
B 1 212 LYS 212 243 243 LYS LYS B . n 
B 1 213 GLN 213 244 244 GLN GLN B . n 
B 1 214 PRO 214 245 245 PRO PRO B . n 
B 1 215 PHE 215 246 246 PHE PHE B . n 
B 1 216 PHE 216 247 247 PHE PHE B . n 
B 1 217 ILE 217 248 248 ILE ILE B . n 
B 1 218 TYR 218 249 249 TYR TYR B . n 
B 1 219 LEU 219 250 250 LEU LEU B . n 
B 1 220 ALA 220 251 251 ALA ALA B . n 
B 1 221 TYR 221 252 252 TYR TYR B . n 
B 1 222 ASN 222 253 253 ASN ASN B . n 
B 1 223 ALA 223 254 254 ALA ALA B . n 
B 1 224 PRO 224 255 255 PRO PRO B . n 
B 1 225 HIS 225 256 256 HIS HIS B . n 
B 1 226 VAL 226 257 257 VAL VAL B . n 
B 1 227 PRO 227 258 258 PRO PRO B . n 
B 1 228 LEU 228 259 259 LEU LEU B . n 
B 1 229 GLN 229 260 260 GLN GLN B . n 
B 1 230 ALA 230 261 261 ALA ALA B . n 
B 1 231 LYS 231 262 262 LYS LYS B . n 
B 1 232 ALA 232 263 263 ALA ALA B . n 
B 1 233 GLU 233 264 264 GLU GLU B . n 
B 1 234 ASP 234 265 265 ASP ASP B . n 
B 1 235 VAL 235 266 266 VAL VAL B . n 
B 1 236 ALA 236 267 267 ALA ALA B . n 
B 1 237 LYS 237 268 268 LYS LYS B . n 
B 1 238 PHE 238 269 269 PHE PHE B . n 
B 1 239 ALA 239 270 270 ALA ALA B . n 
B 1 240 HIS 240 271 271 HIS HIS B . n 
B 1 241 ILE 241 272 272 ILE ILE B . n 
B 1 242 LYS 242 273 273 LYS LYS B . n 
B 1 243 ASP 243 274 274 ASP ASP B . n 
B 1 244 LYS 244 275 275 LYS LYS B . n 
B 1 245 ASP 245 276 276 ASP ASP B . n 
B 1 246 ARG 246 277 277 ARG ARG B . n 
B 1 247 ARG 247 278 278 ARG ARG B . n 
B 1 248 THR 248 279 279 THR THR B . n 
B 1 249 TYR 249 280 280 TYR TYR B . n 
B 1 250 ALA 250 281 281 ALA ALA B . n 
B 1 251 ALA 251 282 282 ALA ALA B . n 
B 1 252 MET 252 283 283 MET MET B . n 
B 1 253 VAL 253 284 284 VAL VAL B . n 
B 1 254 TYR 254 285 285 TYR TYR B . n 
B 1 255 ALA 255 286 286 ALA ALA B . n 
B 1 256 VAL 256 287 287 VAL VAL B . n 
B 1 257 ASP 257 288 288 ASP ASP B . n 
B 1 258 ARG 258 289 289 ARG ARG B . n 
B 1 259 GLY 259 290 290 GLY GLY B . n 
B 1 260 VAL 260 291 291 VAL VAL B . n 
B 1 261 GLY 261 292 292 GLY GLY B . n 
B 1 262 LYS 262 293 293 LYS LYS B . n 
B 1 263 ILE 263 294 294 ILE ILE B . n 
B 1 264 VAL 264 295 295 VAL VAL B . n 
B 1 265 GLN 265 296 296 GLN GLN B . n 
B 1 266 THR 266 297 297 THR THR B . n 
B 1 267 LEU 267 298 298 LEU LEU B . n 
B 1 268 LYS 268 299 299 LYS LYS B . n 
B 1 269 GLU 269 300 300 GLU GLU B . n 
B 1 270 THR 270 301 301 THR THR B . n 
B 1 271 LYS 271 302 302 LYS LYS B . n 
B 1 272 GLN 272 303 303 GLN GLN B . n 
B 1 273 PHE 273 304 304 PHE PHE B . n 
B 1 274 ASP 274 305 305 ASP ASP B . n 
B 1 275 ASN 275 306 306 ASN ASN B . n 
B 1 276 THR 276 307 307 THR THR B . n 
B 1 277 LEU 277 308 308 LEU LEU B . n 
B 1 278 ILE 278 309 309 ILE ILE B . n 
B 1 279 VAL 279 310 310 VAL VAL B . n 
B 1 280 PHE 280 311 311 PHE PHE B . n 
B 1 281 LEU 281 312 312 LEU LEU B . n 
B 1 282 SER 282 313 313 SER SER B . n 
B 1 283 ASP 283 314 314 ASP ASP B . n 
B 1 284 ASN 284 315 315 ASN ASN B . n 
B 1 285 GLY 285 316 316 GLY GLY B . n 
B 1 286 GLY 286 317 317 GLY GLY B . n 
B 1 287 ASN 287 318 318 ASN ASN B . n 
B 1 288 PHE 288 319 319 PHE PHE B . n 
B 1 289 ASN 289 320 320 ASN ASN B . n 
B 1 290 HIS 290 321 321 HIS HIS B . n 
B 1 291 GLY 291 322 322 GLY GLY B . n 
B 1 292 ALA 292 323 323 ALA ALA B . n 
B 1 293 ASN 293 324 324 ASN ASN B . n 
B 1 294 ASN 294 325 325 ASN ASN B . n 
B 1 295 TYR 295 326 326 TYR TYR B . n 
B 1 296 PRO 296 327 327 PRO PRO B . n 
B 1 297 LEU 297 328 328 LEU LEU B . n 
B 1 298 LYS 298 329 329 LYS LYS B . n 
B 1 299 GLY 299 330 330 GLY GLY B . n 
B 1 300 THR 300 331 331 THR THR B . n 
B 1 301 LYS 301 332 332 LYS LYS B . n 
B 1 302 GLY 302 333 333 GLY GLY B . n 
B 1 303 ASP 303 334 334 ASP ASP B . n 
B 1 304 THR 304 335 335 THR THR B . n 
B 1 305 TRP 305 336 336 TRP TRP B . n 
B 1 306 GLU 306 337 337 GLU GLU B . n 
B 1 307 GLY 307 338 338 GLY GLY B . n 
B 1 308 GLY 308 339 339 GLY GLY B . n 
B 1 309 TYR 309 340 340 TYR TYR B . n 
B 1 310 ARG 310 341 341 ARG ARG B . n 
B 1 311 VAL 311 342 342 VAL VAL B . n 
B 1 312 PRO 312 343 343 PRO PRO B . n 
B 1 313 MET 313 344 344 MET MET B . n 
B 1 314 PHE 314 345 345 PHE PHE B . n 
B 1 315 PHE 315 346 346 PHE PHE B . n 
B 1 316 HIS 316 347 347 HIS HIS B . n 
B 1 317 TRP 317 348 348 TRP TRP B . n 
B 1 318 PRO 318 349 349 PRO PRO B . n 
B 1 319 LYS 319 350 350 LYS LYS B . n 
B 1 320 LYS 320 351 351 LYS LYS B . n 
B 1 321 ILE 321 352 352 ILE ILE B . n 
B 1 322 LYS 322 353 353 LYS LYS B . n 
B 1 323 LYS 323 354 354 LYS LYS B . n 
B 1 324 ASP 324 355 355 ASP ASP B . n 
B 1 325 GLN 325 356 356 GLN GLN B . n 
B 1 326 ARG 326 357 357 ARG ARG B . n 
B 1 327 PHE 327 358 358 PHE PHE B . n 
B 1 328 ASP 328 359 359 ASP ASP B . n 
B 1 329 PHE 329 360 360 PHE PHE B . n 
B 1 330 PRO 330 361 361 PRO PRO B . n 
B 1 331 VAL 331 362 362 VAL VAL B . n 
B 1 332 SER 332 363 363 SER SER B . n 
B 1 333 SER 333 364 364 SER SER B . n 
B 1 334 LEU 334 365 365 LEU LEU B . n 
B 1 335 ASP 335 366 366 ASP ASP B . n 
B 1 336 LEU 336 367 367 LEU LEU B . n 
B 1 337 TYR 337 368 368 TYR TYR B . n 
B 1 338 PRO 338 369 369 PRO PRO B . n 
B 1 339 THR 339 370 370 THR THR B . n 
B 1 340 PHE 340 371 371 PHE PHE B . n 
B 1 341 THR 341 372 372 THR THR B . n 
B 1 342 GLY 342 373 373 GLY GLY B . n 
B 1 343 LEU 343 374 374 LEU LEU B . n 
B 1 344 ALA 344 375 375 ALA ALA B . n 
B 1 345 GLU 345 376 376 GLU GLU B . n 
B 1 346 ALA 346 377 377 ALA ALA B . n 
B 1 347 LYS 347 378 378 LYS LYS B . n 
B 1 348 LEU 348 379 379 LEU LEU B . n 
B 1 349 PRO 349 380 380 PRO PRO B . n 
B 1 350 LYS 350 381 381 LYS LYS B . n 
B 1 351 GLY 351 382 382 GLY GLY B . n 
B 1 352 LYS 352 383 383 LYS LYS B . n 
B 1 353 GLN 353 384 384 GLN GLN B . n 
B 1 354 LEU 354 385 385 LEU LEU B . n 
B 1 355 ASP 355 386 386 ASP ASP B . n 
B 1 356 GLY 356 387 387 GLY GLY B . n 
B 1 357 LYS 357 388 388 LYS LYS B . n 
B 1 358 ASN 358 389 389 ASN ASN B . n 
B 1 359 ILE 359 390 390 ILE ILE B . n 
B 1 360 MET 360 391 391 MET MET B . n 
B 1 361 ASP 361 392 392 ASP ASP B . n 
B 1 362 ASP 362 393 393 ASP ASP B . n 
B 1 363 VAL 363 394 394 VAL VAL B . n 
B 1 364 LEU 364 395 395 LEU LEU B . n 
B 1 365 LYS 365 396 396 LYS LYS B . n 
B 1 366 ASN 366 397 397 ASN ASN B . n 
B 1 367 THR 367 398 398 THR THR B . n 
B 1 368 GLU 368 399 399 GLU GLU B . n 
B 1 369 PRO 369 400 400 PRO PRO B . n 
B 1 370 TYR 370 401 401 TYR TYR B . n 
B 1 371 LYS 371 402 402 LYS LYS B . n 
B 1 372 ASP 372 403 403 ASP ASP B . n 
B 1 373 GLU 373 404 404 GLU GLU B . n 
B 1 374 MET 374 405 405 MET MET B . n 
B 1 375 ILE 375 406 406 ILE ILE B . n 
B 1 376 TYR 376 407 407 TYR TYR B . n 
B 1 377 SER 377 408 408 SER SER B . n 
B 1 378 LEU 378 409 409 LEU LEU B . n 
B 1 379 ARG 379 410 410 ARG ARG B . n 
B 1 380 TYR 380 411 411 TYR TYR B . n 
B 1 381 ARG 381 412 412 ARG ARG B . n 
B 1 382 GLU 382 413 413 GLU GLU B . n 
B 1 383 GLY 383 414 414 GLY GLY B . n 
B 1 384 TYR 384 415 415 TYR TYR B . n 
B 1 385 ASN 385 416 416 ASN ASN B . n 
B 1 386 ASP 386 417 417 ASP ASP B . n 
B 1 387 VAL 387 418 418 VAL VAL B . n 
B 1 388 GLY 388 419 419 GLY GLY B . n 
B 1 389 ALA 389 420 420 ALA ALA B . n 
B 1 390 ARG 390 421 421 ARG ARG B . n 
B 1 391 MET 391 422 422 MET MET B . n 
B 1 392 GLY 392 423 423 GLY GLY B . n 
B 1 393 ASP 393 424 424 ASP ASP B . n 
B 1 394 TRP 394 425 425 TRP TRP B . n 
B 1 395 LYS 395 426 426 LYS LYS B . n 
B 1 396 ILE 396 427 427 ILE ILE B . n 
B 1 397 THR 397 428 428 THR THR B . n 
B 1 398 ARG 398 429 429 ARG ARG B . n 
B 1 399 MET 399 430 430 MET MET B . n 
B 1 400 GLY 400 431 431 GLY GLY B . n 
B 1 401 ASN 401 432 432 ASN ASN B . n 
B 1 402 GLU 402 433 433 GLU GLU B . n 
B 1 403 PRO 403 434 434 PRO PRO B . n 
B 1 404 TRP 404 435 435 TRP TRP B . n 
B 1 405 ARG 405 436 436 ARG ARG B . n 
B 1 406 LEU 406 437 437 LEU LEU B . n 
B 1 407 HIS 407 438 438 HIS HIS B . n 
B 1 408 ASN 408 439 439 ASN ASN B . n 
B 1 409 ILE 409 440 440 ILE ILE B . n 
B 1 410 THR 410 441 441 THR THR B . n 
B 1 411 GLN 411 442 442 GLN GLN B . n 
B 1 412 ASP 412 443 443 ASP ASP B . n 
B 1 413 ILE 413 444 444 ILE ILE B . n 
B 1 414 GLY 414 445 445 GLY GLY B . n 
B 1 415 GLU 415 446 446 GLU GLU B . n 
B 1 416 LYS 416 447 447 LYS LYS B . n 
B 1 417 LYS 417 448 448 LYS LYS B . n 
B 1 418 ASN 418 449 449 ASN ASN B . n 
B 1 419 LEU 419 450 450 LEU LEU B . n 
B 1 420 ALA 420 451 451 ALA ALA B . n 
B 1 421 GLY 421 452 452 GLY GLY B . n 
B 1 422 ARG 422 453 453 ARG ARG B . n 
B 1 423 TYR 423 454 454 TYR TYR B . n 
B 1 424 PRO 424 455 455 PRO PRO B . n 
B 1 425 ASP 425 456 456 ASP ASP B . n 
B 1 426 ARG 426 457 457 ARG ARG B . n 
B 1 427 LEU 427 458 458 LEU LEU B . n 
B 1 428 LYS 428 459 459 LYS LYS B . n 
B 1 429 GLU 429 460 460 GLU GLU B . n 
B 1 430 MET 430 461 461 MET MET B . n 
B 1 431 ILE 431 462 462 ILE ILE B . n 
B 1 432 ALA 432 463 463 ALA ALA B . n 
B 1 433 LYS 433 464 464 LYS LYS B . n 
B 1 434 THR 434 465 465 THR THR B . n 
B 1 435 GLN 435 466 466 GLN GLN B . n 
B 1 436 GLU 436 467 467 GLU GLU B . n 
B 1 437 TRP 437 468 468 TRP TRP B . n 
B 1 438 THR 438 469 469 THR THR B . n 
B 1 439 LYS 439 470 470 LYS LYS B . n 
B 1 440 SER 440 471 471 SER SER B . n 
B 1 441 PHE 441 472 472 PHE PHE B . n 
B 1 442 VAL 442 473 473 VAL VAL B . n 
B 1 443 LYS 443 474 474 LYS LYS B . n 
B 1 444 PRO 444 475 475 PRO PRO B . n 
B 1 445 LEU 445 476 476 LEU LEU B . n 
B 1 446 TRP 446 477 477 TRP TRP B . n 
B 1 447 VAL 447 478 478 VAL VAL B . n 
B 1 448 TYR 448 479 479 TYR TYR B . n 
B 1 449 SER 449 480 480 SER SER B . n 
B 1 450 VAL 450 481 481 VAL VAL B . n 
B 1 451 LYS 451 482 482 LYS LYS B . n 
B 1 452 ASP 452 483 483 ASP ASP B . n 
B 1 453 LYS 453 484 484 LYS LYS B . n 
B 1 454 GLU 454 485 485 GLU GLU B . n 
B 1 455 LEU 455 486 486 LEU LEU B . n 
B 1 456 TRP 456 487 487 TRP TRP B . n 
B 1 457 GLU 457 488 488 GLU GLU B . n 
B 1 458 SER 458 489 489 SER SER B . n 
B 1 459 GLY 459 490 490 GLY GLY B . n 
B 1 460 GLN 460 491 491 GLN GLN B . n 
B 1 461 MET 461 492 492 MET MET B . n 
B 1 462 PRO 462 493 493 PRO PRO B . n 
B 1 463 ASN 463 494 494 ASN ASN B . n 
B 1 464 TYR 464 495 495 TYR TYR B . n 
B 1 465 GLU 465 496 496 GLU GLU B . n 
B 1 466 ALA 466 497 497 ALA ALA B . n 
B 1 467 THR 467 498 498 THR THR B . n 
B 1 468 PHE 468 499 499 PHE PHE B . n 
B 1 469 GLU 469 500 500 GLU GLU B . n 
B 1 470 VAL 470 501 501 VAL VAL B . n 
B 1 471 ASP 471 502 502 ASP ASP B . n 
B 1 472 LYS 472 503 503 LYS LYS B . n 
B 1 473 LEU 473 504 504 LEU LEU B . n 
B 1 474 VAL 474 505 505 VAL VAL B . n 
B 1 475 ASP 475 506 506 ASP ASP B . n 
B 1 476 SER 476 507 507 SER SER B . n 
B 1 477 PRO 477 508 508 PRO PRO B . n 
B 1 478 TYR 478 509 509 TYR TYR B . n 
B 1 479 HIS 479 510 ?   ?   ?   B . n 
B 1 480 LYS 480 511 ?   ?   ?   B . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
C 2 G4S 1 G G4S 1 G G4S 4 n 
C 2 DGS 2 G DGS 2 G DGS 3 n 
C 2 GAL 3 G GAL 3 G GAL 2 n 
C 2 DGS 4 G DGS 4 G DGS 1 n 
D 2 G4S 1 H G4S 1 H G4S 4 n 
D 2 DGS 2 H DGS 2 H DGS 3 n 
D 2 GAL 3 H GAL 3 H GAL 2 n 
D 2 DGS 4 H DGS 4 H DGS 1 n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 DGS ? ? DGS ? ? 'SUBJECT OF INVESTIGATION' ? 
2 G4S ? ? G4S ? ? 'SUBJECT OF INVESTIGATION' ? 
3 GAL ? ? GAL ? ? 'SUBJECT OF INVESTIGATION' ? 
4 OSE ? ? OSE ? ? 'SUBJECT OF INVESTIGATION' ? 
5 CA  ? ? CA  ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E  3 CA  1   601  1    CA  CA  A . 
F  4 BR  1   602  1    BR  BR  A . 
G  4 BR  1   603  3    BR  BR  A . 
H  4 BR  1   604  5    BR  BR  A . 
I  5 CL  1   605  2    CL  CL  A . 
J  5 CL  1   606  3    CL  CL  A . 
K  5 CL  1   607  4    CL  CL  A . 
L  5 CL  1   608  5    CL  CL  A . 
M  5 CL  1   609  7    CL  CL  A . 
N  5 CL  1   610  9    CL  CL  A . 
O  6 GOL 1   611  1    GOL GOL A . 
P  6 GOL 1   612  3    GOL GOL A . 
Q  6 GOL 1   613  4    GOL GOL A . 
R  3 CA  1   601  2    CA  CA  B . 
S  4 BR  1   602  2    BR  BR  B . 
T  4 BR  1   603  4    BR  BR  B . 
U  4 BR  1   604  6    BR  BR  B . 
V  5 CL  1   605  1    CL  CL  B . 
W  5 CL  1   606  6    CL  CL  B . 
X  5 CL  1   607  8    CL  CL  B . 
Y  6 GOL 1   608  2    GOL GOL B . 
Z  6 GOL 1   609  5    GOL GOL B . 
AA 6 GOL 1   610  6    GOL GOL B . 
BA 7 HOH 1   701  268  HOH HOH A . 
BA 7 HOH 2   702  823  HOH HOH A . 
BA 7 HOH 3   703  206  HOH HOH A . 
BA 7 HOH 4   704  368  HOH HOH A . 
BA 7 HOH 5   705  1076 HOH HOH A . 
BA 7 HOH 6   706  518  HOH HOH A . 
BA 7 HOH 7   707  793  HOH HOH A . 
BA 7 HOH 8   708  377  HOH HOH A . 
BA 7 HOH 9   709  381  HOH HOH A . 
BA 7 HOH 10  710  386  HOH HOH A . 
BA 7 HOH 11  711  878  HOH HOH A . 
BA 7 HOH 12  712  775  HOH HOH A . 
BA 7 HOH 13  713  144  HOH HOH A . 
BA 7 HOH 14  714  796  HOH HOH A . 
BA 7 HOH 15  715  428  HOH HOH A . 
BA 7 HOH 16  716  108  HOH HOH A . 
BA 7 HOH 17  717  563  HOH HOH A . 
BA 7 HOH 18  718  560  HOH HOH A . 
BA 7 HOH 19  719  498  HOH HOH A . 
BA 7 HOH 20  720  591  HOH HOH A . 
BA 7 HOH 21  721  567  HOH HOH A . 
BA 7 HOH 22  722  299  HOH HOH A . 
BA 7 HOH 23  723  744  HOH HOH A . 
BA 7 HOH 24  724  570  HOH HOH A . 
BA 7 HOH 25  725  723  HOH HOH A . 
BA 7 HOH 26  726  431  HOH HOH A . 
BA 7 HOH 27  727  181  HOH HOH A . 
BA 7 HOH 28  728  283  HOH HOH A . 
BA 7 HOH 29  729  300  HOH HOH A . 
BA 7 HOH 30  730  703  HOH HOH A . 
BA 7 HOH 31  731  485  HOH HOH A . 
BA 7 HOH 32  732  379  HOH HOH A . 
BA 7 HOH 33  733  628  HOH HOH A . 
BA 7 HOH 34  734  282  HOH HOH A . 
BA 7 HOH 35  735  515  HOH HOH A . 
BA 7 HOH 36  736  344  HOH HOH A . 
BA 7 HOH 37  737  358  HOH HOH A . 
BA 7 HOH 38  738  813  HOH HOH A . 
BA 7 HOH 39  739  962  HOH HOH A . 
BA 7 HOH 40  740  1033 HOH HOH A . 
BA 7 HOH 41  741  72   HOH HOH A . 
BA 7 HOH 42  742  118  HOH HOH A . 
BA 7 HOH 43  743  287  HOH HOH A . 
BA 7 HOH 44  744  351  HOH HOH A . 
BA 7 HOH 45  745  784  HOH HOH A . 
BA 7 HOH 46  746  37   HOH HOH A . 
BA 7 HOH 47  747  128  HOH HOH A . 
BA 7 HOH 48  748  559  HOH HOH A . 
BA 7 HOH 49  749  121  HOH HOH A . 
BA 7 HOH 50  750  91   HOH HOH A . 
BA 7 HOH 51  751  18   HOH HOH A . 
BA 7 HOH 52  752  184  HOH HOH A . 
BA 7 HOH 53  753  86   HOH HOH A . 
BA 7 HOH 54  754  422  HOH HOH A . 
BA 7 HOH 55  755  116  HOH HOH A . 
BA 7 HOH 56  756  395  HOH HOH A . 
BA 7 HOH 57  757  477  HOH HOH A . 
BA 7 HOH 58  758  330  HOH HOH A . 
BA 7 HOH 59  759  321  HOH HOH A . 
BA 7 HOH 60  760  323  HOH HOH A . 
BA 7 HOH 61  761  429  HOH HOH A . 
BA 7 HOH 62  762  98   HOH HOH A . 
BA 7 HOH 63  763  7    HOH HOH A . 
BA 7 HOH 64  764  587  HOH HOH A . 
BA 7 HOH 65  765  740  HOH HOH A . 
BA 7 HOH 66  766  68   HOH HOH A . 
BA 7 HOH 67  767  342  HOH HOH A . 
BA 7 HOH 68  768  129  HOH HOH A . 
BA 7 HOH 69  769  117  HOH HOH A . 
BA 7 HOH 70  770  146  HOH HOH A . 
BA 7 HOH 71  771  177  HOH HOH A . 
BA 7 HOH 72  772  10   HOH HOH A . 
BA 7 HOH 73  773  80   HOH HOH A . 
BA 7 HOH 74  774  78   HOH HOH A . 
BA 7 HOH 75  775  23   HOH HOH A . 
BA 7 HOH 76  776  722  HOH HOH A . 
BA 7 HOH 77  777  178  HOH HOH A . 
BA 7 HOH 78  778  188  HOH HOH A . 
BA 7 HOH 79  779  246  HOH HOH A . 
BA 7 HOH 80  780  807  HOH HOH A . 
BA 7 HOH 81  781  179  HOH HOH A . 
BA 7 HOH 82  782  521  HOH HOH A . 
BA 7 HOH 83  783  277  HOH HOH A . 
BA 7 HOH 84  784  707  HOH HOH A . 
BA 7 HOH 85  785  347  HOH HOH A . 
BA 7 HOH 86  786  5    HOH HOH A . 
BA 7 HOH 87  787  861  HOH HOH A . 
BA 7 HOH 88  788  566  HOH HOH A . 
BA 7 HOH 89  789  312  HOH HOH A . 
BA 7 HOH 90  790  971  HOH HOH A . 
BA 7 HOH 91  791  374  HOH HOH A . 
BA 7 HOH 92  792  205  HOH HOH A . 
BA 7 HOH 93  793  264  HOH HOH A . 
BA 7 HOH 94  794  517  HOH HOH A . 
BA 7 HOH 95  795  239  HOH HOH A . 
BA 7 HOH 96  796  2    HOH HOH A . 
BA 7 HOH 97  797  481  HOH HOH A . 
BA 7 HOH 98  798  662  HOH HOH A . 
BA 7 HOH 99  799  139  HOH HOH A . 
BA 7 HOH 100 800  346  HOH HOH A . 
BA 7 HOH 101 801  258  HOH HOH A . 
BA 7 HOH 102 802  284  HOH HOH A . 
BA 7 HOH 103 803  126  HOH HOH A . 
BA 7 HOH 104 804  69   HOH HOH A . 
BA 7 HOH 105 805  210  HOH HOH A . 
BA 7 HOH 106 806  554  HOH HOH A . 
BA 7 HOH 107 807  383  HOH HOH A . 
BA 7 HOH 108 808  64   HOH HOH A . 
BA 7 HOH 109 809  11   HOH HOH A . 
BA 7 HOH 110 810  29   HOH HOH A . 
BA 7 HOH 111 811  844  HOH HOH A . 
BA 7 HOH 112 812  175  HOH HOH A . 
BA 7 HOH 113 813  102  HOH HOH A . 
BA 7 HOH 114 814  406  HOH HOH A . 
BA 7 HOH 115 815  110  HOH HOH A . 
BA 7 HOH 116 816  255  HOH HOH A . 
BA 7 HOH 117 817  748  HOH HOH A . 
BA 7 HOH 118 818  263  HOH HOH A . 
BA 7 HOH 119 819  512  HOH HOH A . 
BA 7 HOH 120 820  14   HOH HOH A . 
BA 7 HOH 121 821  691  HOH HOH A . 
BA 7 HOH 122 822  500  HOH HOH A . 
BA 7 HOH 123 823  141  HOH HOH A . 
BA 7 HOH 124 824  926  HOH HOH A . 
BA 7 HOH 125 825  273  HOH HOH A . 
BA 7 HOH 126 826  318  HOH HOH A . 
BA 7 HOH 127 827  430  HOH HOH A . 
BA 7 HOH 128 828  285  HOH HOH A . 
BA 7 HOH 129 829  50   HOH HOH A . 
BA 7 HOH 130 830  584  HOH HOH A . 
BA 7 HOH 131 831  479  HOH HOH A . 
BA 7 HOH 132 832  761  HOH HOH A . 
BA 7 HOH 133 833  145  HOH HOH A . 
BA 7 HOH 134 834  28   HOH HOH A . 
BA 7 HOH 135 835  355  HOH HOH A . 
BA 7 HOH 136 836  99   HOH HOH A . 
BA 7 HOH 137 837  36   HOH HOH A . 
BA 7 HOH 138 838  577  HOH HOH A . 
BA 7 HOH 139 839  359  HOH HOH A . 
BA 7 HOH 140 840  872  HOH HOH A . 
BA 7 HOH 141 841  173  HOH HOH A . 
BA 7 HOH 142 842  55   HOH HOH A . 
BA 7 HOH 143 843  271  HOH HOH A . 
BA 7 HOH 144 844  305  HOH HOH A . 
BA 7 HOH 145 845  750  HOH HOH A . 
BA 7 HOH 146 846  107  HOH HOH A . 
BA 7 HOH 147 847  482  HOH HOH A . 
BA 7 HOH 148 848  111  HOH HOH A . 
BA 7 HOH 149 849  21   HOH HOH A . 
BA 7 HOH 150 850  130  HOH HOH A . 
BA 7 HOH 151 851  169  HOH HOH A . 
BA 7 HOH 152 852  536  HOH HOH A . 
BA 7 HOH 153 853  320  HOH HOH A . 
BA 7 HOH 154 854  12   HOH HOH A . 
BA 7 HOH 155 855  759  HOH HOH A . 
BA 7 HOH 156 856  396  HOH HOH A . 
BA 7 HOH 157 857  364  HOH HOH A . 
BA 7 HOH 158 858  371  HOH HOH A . 
BA 7 HOH 159 859  568  HOH HOH A . 
BA 7 HOH 160 860  58   HOH HOH A . 
BA 7 HOH 161 861  571  HOH HOH A . 
BA 7 HOH 162 862  419  HOH HOH A . 
BA 7 HOH 163 863  223  HOH HOH A . 
BA 7 HOH 164 864  525  HOH HOH A . 
BA 7 HOH 165 865  248  HOH HOH A . 
BA 7 HOH 166 866  638  HOH HOH A . 
BA 7 HOH 167 867  53   HOH HOH A . 
BA 7 HOH 168 868  220  HOH HOH A . 
BA 7 HOH 169 869  217  HOH HOH A . 
BA 7 HOH 170 870  176  HOH HOH A . 
BA 7 HOH 171 871  104  HOH HOH A . 
BA 7 HOH 172 872  378  HOH HOH A . 
BA 7 HOH 173 873  243  HOH HOH A . 
BA 7 HOH 174 874  611  HOH HOH A . 
BA 7 HOH 175 875  712  HOH HOH A . 
BA 7 HOH 176 876  561  HOH HOH A . 
BA 7 HOH 177 877  60   HOH HOH A . 
BA 7 HOH 178 878  292  HOH HOH A . 
BA 7 HOH 179 879  240  HOH HOH A . 
BA 7 HOH 180 880  576  HOH HOH A . 
BA 7 HOH 181 881  546  HOH HOH A . 
BA 7 HOH 182 882  1021 HOH HOH A . 
BA 7 HOH 183 883  811  HOH HOH A . 
BA 7 HOH 184 884  387  HOH HOH A . 
BA 7 HOH 185 885  519  HOH HOH A . 
BA 7 HOH 186 886  226  HOH HOH A . 
BA 7 HOH 187 887  616  HOH HOH A . 
BA 7 HOH 188 888  523  HOH HOH A . 
BA 7 HOH 189 889  52   HOH HOH A . 
BA 7 HOH 190 890  719  HOH HOH A . 
BA 7 HOH 191 891  987  HOH HOH A . 
BA 7 HOH 192 892  497  HOH HOH A . 
BA 7 HOH 193 893  54   HOH HOH A . 
BA 7 HOH 194 894  522  HOH HOH A . 
BA 7 HOH 195 895  32   HOH HOH A . 
BA 7 HOH 196 896  74   HOH HOH A . 
BA 7 HOH 197 897  242  HOH HOH A . 
BA 7 HOH 198 898  319  HOH HOH A . 
BA 7 HOH 199 899  301  HOH HOH A . 
BA 7 HOH 200 900  964  HOH HOH A . 
BA 7 HOH 201 901  353  HOH HOH A . 
BA 7 HOH 202 902  191  HOH HOH A . 
BA 7 HOH 203 903  93   HOH HOH A . 
BA 7 HOH 204 904  613  HOH HOH A . 
BA 7 HOH 205 905  603  HOH HOH A . 
BA 7 HOH 206 906  261  HOH HOH A . 
BA 7 HOH 207 907  511  HOH HOH A . 
BA 7 HOH 208 908  43   HOH HOH A . 
BA 7 HOH 209 909  961  HOH HOH A . 
BA 7 HOH 210 910  486  HOH HOH A . 
BA 7 HOH 211 911  199  HOH HOH A . 
BA 7 HOH 212 912  555  HOH HOH A . 
BA 7 HOH 213 913  595  HOH HOH A . 
BA 7 HOH 214 914  194  HOH HOH A . 
BA 7 HOH 215 915  363  HOH HOH A . 
BA 7 HOH 216 916  42   HOH HOH A . 
BA 7 HOH 217 917  158  HOH HOH A . 
BA 7 HOH 218 918  923  HOH HOH A . 
BA 7 HOH 219 919  526  HOH HOH A . 
BA 7 HOH 220 920  224  HOH HOH A . 
BA 7 HOH 221 921  15   HOH HOH A . 
BA 7 HOH 222 922  810  HOH HOH A . 
BA 7 HOH 223 923  233  HOH HOH A . 
BA 7 HOH 224 924  529  HOH HOH A . 
BA 7 HOH 225 925  221  HOH HOH A . 
BA 7 HOH 226 926  25   HOH HOH A . 
BA 7 HOH 227 927  564  HOH HOH A . 
BA 7 HOH 228 928  940  HOH HOH A . 
BA 7 HOH 229 929  13   HOH HOH A . 
BA 7 HOH 230 930  241  HOH HOH A . 
BA 7 HOH 231 931  47   HOH HOH A . 
BA 7 HOH 232 932  39   HOH HOH A . 
BA 7 HOH 233 933  231  HOH HOH A . 
BA 7 HOH 234 934  20   HOH HOH A . 
BA 7 HOH 235 935  275  HOH HOH A . 
BA 7 HOH 236 936  597  HOH HOH A . 
BA 7 HOH 237 937  96   HOH HOH A . 
BA 7 HOH 238 938  317  HOH HOH A . 
BA 7 HOH 239 939  763  HOH HOH A . 
BA 7 HOH 240 940  76   HOH HOH A . 
BA 7 HOH 241 941  288  HOH HOH A . 
BA 7 HOH 242 942  928  HOH HOH A . 
BA 7 HOH 243 943  421  HOH HOH A . 
BA 7 HOH 244 944  113  HOH HOH A . 
BA 7 HOH 245 945  527  HOH HOH A . 
BA 7 HOH 246 946  877  HOH HOH A . 
BA 7 HOH 247 947  162  HOH HOH A . 
BA 7 HOH 248 948  313  HOH HOH A . 
BA 7 HOH 249 949  200  HOH HOH A . 
BA 7 HOH 250 950  846  HOH HOH A . 
BA 7 HOH 251 951  575  HOH HOH A . 
BA 7 HOH 252 952  372  HOH HOH A . 
BA 7 HOH 253 953  310  HOH HOH A . 
BA 7 HOH 254 954  757  HOH HOH A . 
BA 7 HOH 255 955  1013 HOH HOH A . 
BA 7 HOH 256 956  161  HOH HOH A . 
BA 7 HOH 257 957  57   HOH HOH A . 
BA 7 HOH 258 958  1090 HOH HOH A . 
BA 7 HOH 259 959  4    HOH HOH A . 
BA 7 HOH 260 960  266  HOH HOH A . 
BA 7 HOH 261 961  225  HOH HOH A . 
BA 7 HOH 262 962  262  HOH HOH A . 
BA 7 HOH 263 963  245  HOH HOH A . 
BA 7 HOH 264 964  152  HOH HOH A . 
BA 7 HOH 265 965  65   HOH HOH A . 
BA 7 HOH 266 966  668  HOH HOH A . 
BA 7 HOH 267 967  506  HOH HOH A . 
BA 7 HOH 268 968  133  HOH HOH A . 
BA 7 HOH 269 969  478  HOH HOH A . 
BA 7 HOH 270 970  624  HOH HOH A . 
BA 7 HOH 271 971  743  HOH HOH A . 
BA 7 HOH 272 972  340  HOH HOH A . 
BA 7 HOH 273 973  480  HOH HOH A . 
BA 7 HOH 274 974  103  HOH HOH A . 
BA 7 HOH 275 975  272  HOH HOH A . 
BA 7 HOH 276 976  40   HOH HOH A . 
BA 7 HOH 277 977  849  HOH HOH A . 
BA 7 HOH 278 978  212  HOH HOH A . 
BA 7 HOH 279 979  801  HOH HOH A . 
BA 7 HOH 280 980  586  HOH HOH A . 
BA 7 HOH 281 981  168  HOH HOH A . 
BA 7 HOH 282 982  572  HOH HOH A . 
BA 7 HOH 283 983  425  HOH HOH A . 
BA 7 HOH 284 984  89   HOH HOH A . 
BA 7 HOH 285 985  942  HOH HOH A . 
BA 7 HOH 286 986  695  HOH HOH A . 
BA 7 HOH 287 987  869  HOH HOH A . 
BA 7 HOH 288 988  598  HOH HOH A . 
BA 7 HOH 289 989  157  HOH HOH A . 
BA 7 HOH 290 990  574  HOH HOH A . 
BA 7 HOH 291 991  630  HOH HOH A . 
BA 7 HOH 292 992  73   HOH HOH A . 
BA 7 HOH 293 993  101  HOH HOH A . 
BA 7 HOH 294 994  265  HOH HOH A . 
BA 7 HOH 295 995  250  HOH HOH A . 
BA 7 HOH 296 996  816  HOH HOH A . 
BA 7 HOH 297 997  109  HOH HOH A . 
BA 7 HOH 298 998  814  HOH HOH A . 
BA 7 HOH 299 999  772  HOH HOH A . 
BA 7 HOH 300 1000 159  HOH HOH A . 
BA 7 HOH 301 1001 1039 HOH HOH A . 
BA 7 HOH 302 1002 120  HOH HOH A . 
BA 7 HOH 303 1003 502  HOH HOH A . 
BA 7 HOH 304 1004 565  HOH HOH A . 
BA 7 HOH 305 1005 83   HOH HOH A . 
BA 7 HOH 306 1006 839  HOH HOH A . 
BA 7 HOH 307 1007 648  HOH HOH A . 
BA 7 HOH 308 1008 362  HOH HOH A . 
BA 7 HOH 309 1009 234  HOH HOH A . 
BA 7 HOH 310 1010 578  HOH HOH A . 
BA 7 HOH 311 1011 211  HOH HOH A . 
BA 7 HOH 312 1012 357  HOH HOH A . 
BA 7 HOH 313 1013 599  HOH HOH A . 
BA 7 HOH 314 1014 1025 HOH HOH A . 
BA 7 HOH 315 1015 693  HOH HOH A . 
BA 7 HOH 316 1016 483  HOH HOH A . 
BA 7 HOH 317 1017 727  HOH HOH A . 
BA 7 HOH 318 1018 893  HOH HOH A . 
BA 7 HOH 319 1019 912  HOH HOH A . 
BA 7 HOH 320 1020 508  HOH HOH A . 
BA 7 HOH 321 1021 402  HOH HOH A . 
BA 7 HOH 322 1022 59   HOH HOH A . 
BA 7 HOH 323 1023 773  HOH HOH A . 
BA 7 HOH 324 1024 155  HOH HOH A . 
BA 7 HOH 325 1025 356  HOH HOH A . 
BA 7 HOH 326 1026 160  HOH HOH A . 
BA 7 HOH 327 1027 936  HOH HOH A . 
BA 7 HOH 328 1028 768  HOH HOH A . 
BA 7 HOH 329 1029 938  HOH HOH A . 
BA 7 HOH 330 1030 658  HOH HOH A . 
BA 7 HOH 331 1031 995  HOH HOH A . 
BA 7 HOH 332 1032 975  HOH HOH A . 
BA 7 HOH 333 1033 404  HOH HOH A . 
BA 7 HOH 334 1034 92   HOH HOH A . 
BA 7 HOH 335 1035 361  HOH HOH A . 
BA 7 HOH 336 1036 853  HOH HOH A . 
BA 7 HOH 337 1037 812  HOH HOH A . 
BA 7 HOH 338 1038 1062 HOH HOH A . 
BA 7 HOH 339 1039 1072 HOH HOH A . 
BA 7 HOH 340 1040 558  HOH HOH A . 
BA 7 HOH 341 1041 215  HOH HOH A . 
BA 7 HOH 342 1042 639  HOH HOH A . 
BA 7 HOH 343 1043 947  HOH HOH A . 
BA 7 HOH 344 1044 348  HOH HOH A . 
BA 7 HOH 345 1045 1057 HOH HOH A . 
BA 7 HOH 346 1046 1054 HOH HOH A . 
BA 7 HOH 347 1047 629  HOH HOH A . 
BA 7 HOH 348 1048 678  HOH HOH A . 
BA 7 HOH 349 1049 862  HOH HOH A . 
BA 7 HOH 350 1050 1030 HOH HOH A . 
BA 7 HOH 351 1051 424  HOH HOH A . 
BA 7 HOH 352 1052 684  HOH HOH A . 
BA 7 HOH 353 1053 1032 HOH HOH A . 
BA 7 HOH 354 1054 17   HOH HOH A . 
BA 7 HOH 355 1055 1086 HOH HOH A . 
BA 7 HOH 356 1056 803  HOH HOH A . 
BA 7 HOH 357 1057 329  HOH HOH A . 
BA 7 HOH 358 1058 621  HOH HOH A . 
BA 7 HOH 359 1059 815  HOH HOH A . 
BA 7 HOH 360 1060 671  HOH HOH A . 
BA 7 HOH 361 1061 920  HOH HOH A . 
BA 7 HOH 362 1062 997  HOH HOH A . 
BA 7 HOH 363 1063 800  HOH HOH A . 
BA 7 HOH 364 1064 380  HOH HOH A . 
BA 7 HOH 365 1065 976  HOH HOH A . 
BA 7 HOH 366 1066 338  HOH HOH A . 
BA 7 HOH 367 1067 646  HOH HOH A . 
BA 7 HOH 368 1068 650  HOH HOH A . 
BA 7 HOH 369 1069 499  HOH HOH A . 
BA 7 HOH 370 1070 960  HOH HOH A . 
BA 7 HOH 371 1071 663  HOH HOH A . 
BA 7 HOH 372 1072 543  HOH HOH A . 
BA 7 HOH 373 1073 656  HOH HOH A . 
BA 7 HOH 374 1074 336  HOH HOH A . 
BA 7 HOH 375 1075 230  HOH HOH A . 
BA 7 HOH 376 1076 804  HOH HOH A . 
BA 7 HOH 377 1077 556  HOH HOH A . 
BA 7 HOH 378 1078 334  HOH HOH A . 
BA 7 HOH 379 1079 819  HOH HOH A . 
BA 7 HOH 380 1080 937  HOH HOH A . 
BA 7 HOH 381 1081 780  HOH HOH A . 
BA 7 HOH 382 1082 927  HOH HOH A . 
BA 7 HOH 383 1083 747  HOH HOH A . 
BA 7 HOH 384 1084 306  HOH HOH A . 
BA 7 HOH 385 1085 370  HOH HOH A . 
BA 7 HOH 386 1086 1075 HOH HOH A . 
BA 7 HOH 387 1087 931  HOH HOH A . 
BA 7 HOH 388 1088 573  HOH HOH A . 
BA 7 HOH 389 1089 941  HOH HOH A . 
BA 7 HOH 390 1090 405  HOH HOH A . 
BA 7 HOH 391 1091 969  HOH HOH A . 
BA 7 HOH 392 1092 685  HOH HOH A . 
BA 7 HOH 393 1093 151  HOH HOH A . 
BA 7 HOH 394 1094 948  HOH HOH A . 
BA 7 HOH 395 1095 1079 HOH HOH A . 
BA 7 HOH 396 1096 945  HOH HOH A . 
BA 7 HOH 397 1097 1024 HOH HOH A . 
BA 7 HOH 398 1098 1065 HOH HOH A . 
BA 7 HOH 399 1099 898  HOH HOH A . 
BA 7 HOH 400 1100 112  HOH HOH A . 
BA 7 HOH 401 1101 257  HOH HOH A . 
BA 7 HOH 402 1102 737  HOH HOH A . 
BA 7 HOH 403 1103 1019 HOH HOH A . 
BA 7 HOH 404 1104 659  HOH HOH A . 
BA 7 HOH 405 1105 1093 HOH HOH A . 
BA 7 HOH 406 1106 1026 HOH HOH A . 
BA 7 HOH 407 1107 725  HOH HOH A . 
BA 7 HOH 408 1108 401  HOH HOH A . 
BA 7 HOH 409 1109 544  HOH HOH A . 
BA 7 HOH 410 1110 432  HOH HOH A . 
BA 7 HOH 411 1111 808  HOH HOH A . 
BA 7 HOH 412 1112 1092 HOH HOH A . 
BA 7 HOH 413 1113 863  HOH HOH A . 
BA 7 HOH 414 1114 989  HOH HOH A . 
BA 7 HOH 415 1115 1088 HOH HOH A . 
BA 7 HOH 416 1116 755  HOH HOH A . 
BA 7 HOH 417 1117 197  HOH HOH A . 
BA 7 HOH 418 1118 557  HOH HOH A . 
BA 7 HOH 419 1119 817  HOH HOH A . 
BA 7 HOH 420 1120 172  HOH HOH A . 
BA 7 HOH 421 1121 476  HOH HOH A . 
BA 7 HOH 422 1122 1031 HOH HOH A . 
BA 7 HOH 423 1123 706  HOH HOH A . 
BA 7 HOH 424 1124 778  HOH HOH A . 
BA 7 HOH 425 1125 410  HOH HOH A . 
BA 7 HOH 426 1126 504  HOH HOH A . 
BA 7 HOH 427 1127 799  HOH HOH A . 
BA 7 HOH 428 1128 1066 HOH HOH A . 
BA 7 HOH 429 1129 746  HOH HOH A . 
BA 7 HOH 430 1130 189  HOH HOH A . 
BA 7 HOH 431 1131 917  HOH HOH A . 
BA 7 HOH 432 1132 949  HOH HOH A . 
BA 7 HOH 433 1133 683  HOH HOH A . 
BA 7 HOH 434 1134 721  HOH HOH A . 
BA 7 HOH 435 1135 423  HOH HOH A . 
BA 7 HOH 436 1136 1028 HOH HOH A . 
BA 7 HOH 437 1137 360  HOH HOH A . 
BA 7 HOH 438 1138 214  HOH HOH A . 
BA 7 HOH 439 1139 736  HOH HOH A . 
BA 7 HOH 440 1140 418  HOH HOH A . 
BA 7 HOH 441 1141 373  HOH HOH A . 
BA 7 HOH 442 1142 870  HOH HOH A . 
BA 7 HOH 443 1143 349  HOH HOH A . 
BA 7 HOH 444 1144 1016 HOH HOH A . 
BA 7 HOH 445 1145 537  HOH HOH A . 
BA 7 HOH 446 1146 420  HOH HOH A . 
BA 7 HOH 447 1147 958  HOH HOH A . 
BA 7 HOH 448 1148 507  HOH HOH A . 
BA 7 HOH 449 1149 907  HOH HOH A . 
BA 7 HOH 450 1150 375  HOH HOH A . 
BA 7 HOH 451 1151 397  HOH HOH A . 
BA 7 HOH 452 1152 185  HOH HOH A . 
BA 7 HOH 453 1153 411  HOH HOH A . 
BA 7 HOH 454 1154 562  HOH HOH A . 
BA 7 HOH 455 1155 692  HOH HOH A . 
BA 7 HOH 456 1156 704  HOH HOH A . 
BA 7 HOH 457 1157 643  HOH HOH A . 
BA 7 HOH 458 1158 332  HOH HOH A . 
BA 7 HOH 459 1159 1029 HOH HOH A . 
BA 7 HOH 460 1160 649  HOH HOH A . 
BA 7 HOH 461 1161 394  HOH HOH A . 
BA 7 HOH 462 1162 688  HOH HOH A . 
BA 7 HOH 463 1163 731  HOH HOH A . 
BA 7 HOH 464 1164 868  HOH HOH A . 
BA 7 HOH 465 1165 631  HOH HOH A . 
BA 7 HOH 466 1166 1060 HOH HOH A . 
BA 7 HOH 467 1167 914  HOH HOH A . 
BA 7 HOH 468 1168 1027 HOH HOH A . 
BA 7 HOH 469 1169 874  HOH HOH A . 
BA 7 HOH 470 1170 883  HOH HOH A . 
BA 7 HOH 471 1171 974  HOH HOH A . 
CA 7 HOH 1   701  786  HOH HOH B . 
CA 7 HOH 2   702  1022 HOH HOH B . 
CA 7 HOH 3   703  1015 HOH HOH B . 
CA 7 HOH 4   704  652  HOH HOH B . 
CA 7 HOH 5   705  911  HOH HOH B . 
CA 7 HOH 6   706  467  HOH HOH B . 
CA 7 HOH 7   707  311  HOH HOH B . 
CA 7 HOH 8   708  1070 HOH HOH B . 
CA 7 HOH 9   709  680  HOH HOH B . 
CA 7 HOH 10  710  785  HOH HOH B . 
CA 7 HOH 11  711  932  HOH HOH B . 
CA 7 HOH 12  712  531  HOH HOH B . 
CA 7 HOH 13  713  660  HOH HOH B . 
CA 7 HOH 14  714  216  HOH HOH B . 
CA 7 HOH 15  715  654  HOH HOH B . 
CA 7 HOH 16  716  494  HOH HOH B . 
CA 7 HOH 17  717  449  HOH HOH B . 
CA 7 HOH 18  718  669  HOH HOH B . 
CA 7 HOH 19  719  580  HOH HOH B . 
CA 7 HOH 20  720  164  HOH HOH B . 
CA 7 HOH 21  721  604  HOH HOH B . 
CA 7 HOH 22  722  400  HOH HOH B . 
CA 7 HOH 23  723  393  HOH HOH B . 
CA 7 HOH 24  724  602  HOH HOH B . 
CA 7 HOH 25  725  274  HOH HOH B . 
CA 7 HOH 26  726  303  HOH HOH B . 
CA 7 HOH 27  727  441  HOH HOH B . 
CA 7 HOH 28  728  465  HOH HOH B . 
CA 7 HOH 29  729  439  HOH HOH B . 
CA 7 HOH 30  730  606  HOH HOH B . 
CA 7 HOH 31  731  881  HOH HOH B . 
CA 7 HOH 32  732  627  HOH HOH B . 
CA 7 HOH 33  733  509  HOH HOH B . 
CA 7 HOH 34  734  470  HOH HOH B . 
CA 7 HOH 35  735  528  HOH HOH B . 
CA 7 HOH 36  736  845  HOH HOH B . 
CA 7 HOH 37  737  45   HOH HOH B . 
CA 7 HOH 38  738  732  HOH HOH B . 
CA 7 HOH 39  739  134  HOH HOH B . 
CA 7 HOH 40  740  97   HOH HOH B . 
CA 7 HOH 41  741  618  HOH HOH B . 
CA 7 HOH 42  742  623  HOH HOH B . 
CA 7 HOH 43  743  442  HOH HOH B . 
CA 7 HOH 44  744  433  HOH HOH B . 
CA 7 HOH 45  745  106  HOH HOH B . 
CA 7 HOH 46  746  180  HOH HOH B . 
CA 7 HOH 47  747  463  HOH HOH B . 
CA 7 HOH 48  748  589  HOH HOH B . 
CA 7 HOH 49  749  513  HOH HOH B . 
CA 7 HOH 50  750  333  HOH HOH B . 
CA 7 HOH 51  751  31   HOH HOH B . 
CA 7 HOH 52  752  385  HOH HOH B . 
CA 7 HOH 53  753  135  HOH HOH B . 
CA 7 HOH 54  754  847  HOH HOH B . 
CA 7 HOH 55  755  496  HOH HOH B . 
CA 7 HOH 56  756  514  HOH HOH B . 
CA 7 HOH 57  757  22   HOH HOH B . 
CA 7 HOH 58  758  24   HOH HOH B . 
CA 7 HOH 59  759  1    HOH HOH B . 
CA 7 HOH 60  760  612  HOH HOH B . 
CA 7 HOH 61  761  67   HOH HOH B . 
CA 7 HOH 62  762  186  HOH HOH B . 
CA 7 HOH 63  763  530  HOH HOH B . 
CA 7 HOH 64  764  147  HOH HOH B . 
CA 7 HOH 65  765  131  HOH HOH B . 
CA 7 HOH 66  766  860  HOH HOH B . 
CA 7 HOH 67  767  291  HOH HOH B . 
CA 7 HOH 68  768  132  HOH HOH B . 
CA 7 HOH 69  769  758  HOH HOH B . 
CA 7 HOH 70  770  855  HOH HOH B . 
CA 7 HOH 71  771  797  HOH HOH B . 
CA 7 HOH 72  772  726  HOH HOH B . 
CA 7 HOH 73  773  308  HOH HOH B . 
CA 7 HOH 74  774  66   HOH HOH B . 
CA 7 HOH 75  775  825  HOH HOH B . 
CA 7 HOH 76  776  251  HOH HOH B . 
CA 7 HOH 77  777  30   HOH HOH B . 
CA 7 HOH 78  778  9    HOH HOH B . 
CA 7 HOH 79  779  33   HOH HOH B . 
CA 7 HOH 80  780  174  HOH HOH B . 
CA 7 HOH 81  781  454  HOH HOH B . 
CA 7 HOH 82  782  127  HOH HOH B . 
CA 7 HOH 83  783  85   HOH HOH B . 
CA 7 HOH 84  784  399  HOH HOH B . 
CA 7 HOH 85  785  124  HOH HOH B . 
CA 7 HOH 86  786  625  HOH HOH B . 
CA 7 HOH 87  787  588  HOH HOH B . 
CA 7 HOH 88  788  48   HOH HOH B . 
CA 7 HOH 89  789  632  HOH HOH B . 
CA 7 HOH 90  790  460  HOH HOH B . 
CA 7 HOH 91  791  640  HOH HOH B . 
CA 7 HOH 92  792  661  HOH HOH B . 
CA 7 HOH 93  793  115  HOH HOH B . 
CA 7 HOH 94  794  193  HOH HOH B . 
CA 7 HOH 95  795  488  HOH HOH B . 
CA 7 HOH 96  796  289  HOH HOH B . 
CA 7 HOH 97  797  196  HOH HOH B . 
CA 7 HOH 98  798  34   HOH HOH B . 
CA 7 HOH 99  799  190  HOH HOH B . 
CA 7 HOH 100 800  3    HOH HOH B . 
CA 7 HOH 101 801  187  HOH HOH B . 
CA 7 HOH 102 802  19   HOH HOH B . 
CA 7 HOH 103 803  35   HOH HOH B . 
CA 7 HOH 104 804  593  HOH HOH B . 
CA 7 HOH 105 805  195  HOH HOH B . 
CA 7 HOH 106 806  455  HOH HOH B . 
CA 7 HOH 107 807  535  HOH HOH B . 
CA 7 HOH 108 808  298  HOH HOH B . 
CA 7 HOH 109 809  325  HOH HOH B . 
CA 7 HOH 110 810  182  HOH HOH B . 
CA 7 HOH 111 811  75   HOH HOH B . 
CA 7 HOH 112 812  437  HOH HOH B . 
CA 7 HOH 113 813  451  HOH HOH B . 
CA 7 HOH 114 814  542  HOH HOH B . 
CA 7 HOH 115 815  51   HOH HOH B . 
CA 7 HOH 116 816  607  HOH HOH B . 
CA 7 HOH 117 817  539  HOH HOH B . 
CA 7 HOH 118 818  474  HOH HOH B . 
CA 7 HOH 119 819  538  HOH HOH B . 
CA 7 HOH 120 820  44   HOH HOH B . 
CA 7 HOH 121 821  296  HOH HOH B . 
CA 7 HOH 122 822  551  HOH HOH B . 
CA 7 HOH 123 823  600  HOH HOH B . 
CA 7 HOH 124 824  608  HOH HOH B . 
CA 7 HOH 125 825  635  HOH HOH B . 
CA 7 HOH 126 826  345  HOH HOH B . 
CA 7 HOH 127 827  8    HOH HOH B . 
CA 7 HOH 128 828  63   HOH HOH B . 
CA 7 HOH 129 829  871  HOH HOH B . 
CA 7 HOH 130 830  438  HOH HOH B . 
CA 7 HOH 131 831  138  HOH HOH B . 
CA 7 HOH 132 832  335  HOH HOH B . 
CA 7 HOH 133 833  229  HOH HOH B . 
CA 7 HOH 134 834  38   HOH HOH B . 
CA 7 HOH 135 835  873  HOH HOH B . 
CA 7 HOH 136 836  666  HOH HOH B . 
CA 7 HOH 137 837  81   HOH HOH B . 
CA 7 HOH 138 838  150  HOH HOH B . 
CA 7 HOH 139 839  553  HOH HOH B . 
CA 7 HOH 140 840  70   HOH HOH B . 
CA 7 HOH 141 841  331  HOH HOH B . 
CA 7 HOH 142 842  620  HOH HOH B . 
CA 7 HOH 143 843  105  HOH HOH B . 
CA 7 HOH 144 844  614  HOH HOH B . 
CA 7 HOH 145 845  859  HOH HOH B . 
CA 7 HOH 146 846  493  HOH HOH B . 
CA 7 HOH 147 847  457  HOH HOH B . 
CA 7 HOH 148 848  156  HOH HOH B . 
CA 7 HOH 149 849  324  HOH HOH B . 
CA 7 HOH 150 850  88   HOH HOH B . 
CA 7 HOH 151 851  222  HOH HOH B . 
CA 7 HOH 152 852  208  HOH HOH B . 
CA 7 HOH 153 853  435  HOH HOH B . 
CA 7 HOH 154 854  392  HOH HOH B . 
CA 7 HOH 155 855  388  HOH HOH B . 
CA 7 HOH 156 856  569  HOH HOH B . 
CA 7 HOH 157 857  254  HOH HOH B . 
CA 7 HOH 158 858  209  HOH HOH B . 
CA 7 HOH 159 859  142  HOH HOH B . 
CA 7 HOH 160 860  836  HOH HOH B . 
CA 7 HOH 161 861  293  HOH HOH B . 
CA 7 HOH 162 862  366  HOH HOH B . 
CA 7 HOH 163 863  167  HOH HOH B . 
CA 7 HOH 164 864  137  HOH HOH B . 
CA 7 HOH 165 865  505  HOH HOH B . 
CA 7 HOH 166 866  510  HOH HOH B . 
CA 7 HOH 167 867  675  HOH HOH B . 
CA 7 HOH 168 868  170  HOH HOH B . 
CA 7 HOH 169 869  682  HOH HOH B . 
CA 7 HOH 170 870  596  HOH HOH B . 
CA 7 HOH 171 871  202  HOH HOH B . 
CA 7 HOH 172 872  79   HOH HOH B . 
CA 7 HOH 173 873  165  HOH HOH B . 
CA 7 HOH 174 874  552  HOH HOH B . 
CA 7 HOH 175 875  951  HOH HOH B . 
CA 7 HOH 176 876  427  HOH HOH B . 
CA 7 HOH 177 877  450  HOH HOH B . 
CA 7 HOH 178 878  269  HOH HOH B . 
CA 7 HOH 179 879  848  HOH HOH B . 
CA 7 HOH 180 880  495  HOH HOH B . 
CA 7 HOH 181 881  82   HOH HOH B . 
CA 7 HOH 182 882  626  HOH HOH B . 
CA 7 HOH 183 883  876  HOH HOH B . 
CA 7 HOH 184 884  276  HOH HOH B . 
CA 7 HOH 185 885  207  HOH HOH B . 
CA 7 HOH 186 886  622  HOH HOH B . 
CA 7 HOH 187 887  609  HOH HOH B . 
CA 7 HOH 188 888  452  HOH HOH B . 
CA 7 HOH 189 889  237  HOH HOH B . 
CA 7 HOH 190 890  122  HOH HOH B . 
CA 7 HOH 191 891  462  HOH HOH B . 
CA 7 HOH 192 892  26   HOH HOH B . 
CA 7 HOH 193 893  468  HOH HOH B . 
CA 7 HOH 194 894  534  HOH HOH B . 
CA 7 HOH 195 895  889  HOH HOH B . 
CA 7 HOH 196 896  267  HOH HOH B . 
CA 7 HOH 197 897  143  HOH HOH B . 
CA 7 HOH 198 898  302  HOH HOH B . 
CA 7 HOH 199 899  41   HOH HOH B . 
CA 7 HOH 200 900  749  HOH HOH B . 
CA 7 HOH 201 901  259  HOH HOH B . 
CA 7 HOH 202 902  610  HOH HOH B . 
CA 7 HOH 203 903  192  HOH HOH B . 
CA 7 HOH 204 904  148  HOH HOH B . 
CA 7 HOH 205 905  446  HOH HOH B . 
CA 7 HOH 206 906  698  HOH HOH B . 
CA 7 HOH 207 907  540  HOH HOH B . 
CA 7 HOH 208 908  249  HOH HOH B . 
CA 7 HOH 209 909  466  HOH HOH B . 
CA 7 HOH 210 910  670  HOH HOH B . 
CA 7 HOH 211 911  1052 HOH HOH B . 
CA 7 HOH 212 912  440  HOH HOH B . 
CA 7 HOH 213 913  717  HOH HOH B . 
CA 7 HOH 214 914  545  HOH HOH B . 
CA 7 HOH 215 915  818  HOH HOH B . 
CA 7 HOH 216 916  140  HOH HOH B . 
CA 7 HOH 217 917  350  HOH HOH B . 
CA 7 HOH 218 918  87   HOH HOH B . 
CA 7 HOH 219 919  653  HOH HOH B . 
CA 7 HOH 220 920  453  HOH HOH B . 
CA 7 HOH 221 921  503  HOH HOH B . 
CA 7 HOH 222 922  119  HOH HOH B . 
CA 7 HOH 223 923  136  HOH HOH B . 
CA 7 HOH 224 924  384  HOH HOH B . 
CA 7 HOH 225 925  590  HOH HOH B . 
CA 7 HOH 226 926  236  HOH HOH B . 
CA 7 HOH 227 927  114  HOH HOH B . 
CA 7 HOH 228 928  592  HOH HOH B . 
CA 7 HOH 229 929  326  HOH HOH B . 
CA 7 HOH 230 930  916  HOH HOH B . 
CA 7 HOH 231 931  278  HOH HOH B . 
CA 7 HOH 232 932  252  HOH HOH B . 
CA 7 HOH 233 933  365  HOH HOH B . 
CA 7 HOH 234 934  235  HOH HOH B . 
CA 7 HOH 235 935  447  HOH HOH B . 
CA 7 HOH 236 936  27   HOH HOH B . 
CA 7 HOH 237 937  352  HOH HOH B . 
CA 7 HOH 238 938  550  HOH HOH B . 
CA 7 HOH 239 939  733  HOH HOH B . 
CA 7 HOH 240 940  739  HOH HOH B . 
CA 7 HOH 241 941  789  HOH HOH B . 
CA 7 HOH 242 942  687  HOH HOH B . 
CA 7 HOH 243 943  633  HOH HOH B . 
CA 7 HOH 244 944  123  HOH HOH B . 
CA 7 HOH 245 945  256  HOH HOH B . 
CA 7 HOH 246 946  369  HOH HOH B . 
CA 7 HOH 247 947  314  HOH HOH B . 
CA 7 HOH 248 948  771  HOH HOH B . 
CA 7 HOH 249 949  636  HOH HOH B . 
CA 7 HOH 250 950  665  HOH HOH B . 
CA 7 HOH 251 951  637  HOH HOH B . 
CA 7 HOH 252 952  415  HOH HOH B . 
CA 7 HOH 253 953  594  HOH HOH B . 
CA 7 HOH 254 954  826  HOH HOH B . 
CA 7 HOH 255 955  163  HOH HOH B . 
CA 7 HOH 256 956  61   HOH HOH B . 
CA 7 HOH 257 957  16   HOH HOH B . 
CA 7 HOH 258 958  461  HOH HOH B . 
CA 7 HOH 259 959  201  HOH HOH B . 
CA 7 HOH 260 960  62   HOH HOH B . 
CA 7 HOH 261 961  484  HOH HOH B . 
CA 7 HOH 262 962  71   HOH HOH B . 
CA 7 HOH 263 963  516  HOH HOH B . 
CA 7 HOH 264 964  46   HOH HOH B . 
CA 7 HOH 265 965  875  HOH HOH B . 
CA 7 HOH 266 966  1008 HOH HOH B . 
CA 7 HOH 267 967  328  HOH HOH B . 
CA 7 HOH 268 968  149  HOH HOH B . 
CA 7 HOH 269 969  232  HOH HOH B . 
CA 7 HOH 270 970  94   HOH HOH B . 
CA 7 HOH 271 971  766  HOH HOH B . 
CA 7 HOH 272 972  694  HOH HOH B . 
CA 7 HOH 273 973  890  HOH HOH B . 
CA 7 HOH 274 974  939  HOH HOH B . 
CA 7 HOH 275 975  459  HOH HOH B . 
CA 7 HOH 276 976  416  HOH HOH B . 
CA 7 HOH 277 977  6    HOH HOH B . 
CA 7 HOH 278 978  583  HOH HOH B . 
CA 7 HOH 279 979  919  HOH HOH B . 
CA 7 HOH 280 980  501  HOH HOH B . 
CA 7 HOH 281 981  984  HOH HOH B . 
CA 7 HOH 282 982  892  HOH HOH B . 
CA 7 HOH 283 983  490  HOH HOH B . 
CA 7 HOH 284 984  270  HOH HOH B . 
CA 7 HOH 285 985  125  HOH HOH B . 
CA 7 HOH 286 986  1005 HOH HOH B . 
CA 7 HOH 287 987  166  HOH HOH B . 
CA 7 HOH 288 988  339  HOH HOH B . 
CA 7 HOH 289 989  617  HOH HOH B . 
CA 7 HOH 290 990  367  HOH HOH B . 
CA 7 HOH 291 991  77   HOH HOH B . 
CA 7 HOH 292 992  154  HOH HOH B . 
CA 7 HOH 293 993  204  HOH HOH B . 
CA 7 HOH 294 994  473  HOH HOH B . 
CA 7 HOH 295 995  171  HOH HOH B . 
CA 7 HOH 296 996  218  HOH HOH B . 
CA 7 HOH 297 997  475  HOH HOH B . 
CA 7 HOH 298 998  56   HOH HOH B . 
CA 7 HOH 299 999  228  HOH HOH B . 
CA 7 HOH 300 1000 524  HOH HOH B . 
CA 7 HOH 301 1001 260  HOH HOH B . 
CA 7 HOH 302 1002 864  HOH HOH B . 
CA 7 HOH 303 1003 679  HOH HOH B . 
CA 7 HOH 304 1004 456  HOH HOH B . 
CA 7 HOH 305 1005 280  HOH HOH B . 
CA 7 HOH 306 1006 213  HOH HOH B . 
CA 7 HOH 307 1007 788  HOH HOH B . 
CA 7 HOH 308 1008 857  HOH HOH B . 
CA 7 HOH 309 1009 491  HOH HOH B . 
CA 7 HOH 310 1010 741  HOH HOH B . 
CA 7 HOH 311 1011 153  HOH HOH B . 
CA 7 HOH 312 1012 720  HOH HOH B . 
CA 7 HOH 313 1013 409  HOH HOH B . 
CA 7 HOH 314 1014 489  HOH HOH B . 
CA 7 HOH 315 1015 579  HOH HOH B . 
CA 7 HOH 316 1016 824  HOH HOH B . 
CA 7 HOH 317 1017 764  HOH HOH B . 
CA 7 HOH 318 1018 279  HOH HOH B . 
CA 7 HOH 319 1019 247  HOH HOH B . 
CA 7 HOH 320 1020 533  HOH HOH B . 
CA 7 HOH 321 1021 100  HOH HOH B . 
CA 7 HOH 322 1022 49   HOH HOH B . 
CA 7 HOH 323 1023 398  HOH HOH B . 
CA 7 HOH 324 1024 582  HOH HOH B . 
CA 7 HOH 325 1025 888  HOH HOH B . 
CA 7 HOH 326 1026 954  HOH HOH B . 
CA 7 HOH 327 1027 615  HOH HOH B . 
CA 7 HOH 328 1028 852  HOH HOH B . 
CA 7 HOH 329 1029 710  HOH HOH B . 
CA 7 HOH 330 1030 992  HOH HOH B . 
CA 7 HOH 331 1031 238  HOH HOH B . 
CA 7 HOH 332 1032 304  HOH HOH B . 
CA 7 HOH 333 1033 294  HOH HOH B . 
CA 7 HOH 334 1034 376  HOH HOH B . 
CA 7 HOH 335 1035 935  HOH HOH B . 
CA 7 HOH 336 1036 469  HOH HOH B . 
CA 7 HOH 337 1037 701  HOH HOH B . 
CA 7 HOH 338 1038 315  HOH HOH B . 
CA 7 HOH 339 1039 343  HOH HOH B . 
CA 7 HOH 340 1040 532  HOH HOH B . 
CA 7 HOH 341 1041 762  HOH HOH B . 
CA 7 HOH 342 1042 464  HOH HOH B . 
CA 7 HOH 343 1043 407  HOH HOH B . 
CA 7 HOH 344 1044 1089 HOH HOH B . 
CA 7 HOH 345 1045 203  HOH HOH B . 
CA 7 HOH 346 1046 856  HOH HOH B . 
CA 7 HOH 347 1047 887  HOH HOH B . 
CA 7 HOH 348 1048 1068 HOH HOH B . 
CA 7 HOH 349 1049 341  HOH HOH B . 
CA 7 HOH 350 1050 619  HOH HOH B . 
CA 7 HOH 351 1051 84   HOH HOH B . 
CA 7 HOH 352 1052 1067 HOH HOH B . 
CA 7 HOH 353 1053 885  HOH HOH B . 
CA 7 HOH 354 1054 738  HOH HOH B . 
CA 7 HOH 355 1055 389  HOH HOH B . 
CA 7 HOH 356 1056 760  HOH HOH B . 
CA 7 HOH 357 1057 585  HOH HOH B . 
CA 7 HOH 358 1058 1037 HOH HOH B . 
CA 7 HOH 359 1059 843  HOH HOH B . 
CA 7 HOH 360 1060 1083 HOH HOH B . 
CA 7 HOH 361 1061 753  HOH HOH B . 
CA 7 HOH 362 1062 918  HOH HOH B . 
CA 7 HOH 363 1063 448  HOH HOH B . 
CA 7 HOH 364 1064 767  HOH HOH B . 
CA 7 HOH 365 1065 1040 HOH HOH B . 
CA 7 HOH 366 1066 95   HOH HOH B . 
CA 7 HOH 367 1067 842  HOH HOH B . 
CA 7 HOH 368 1068 756  HOH HOH B . 
CA 7 HOH 369 1069 1009 HOH HOH B . 
CA 7 HOH 370 1070 549  HOH HOH B . 
CA 7 HOH 371 1071 950  HOH HOH B . 
CA 7 HOH 372 1072 915  HOH HOH B . 
CA 7 HOH 373 1073 921  HOH HOH B . 
CA 7 HOH 374 1074 281  HOH HOH B . 
CA 7 HOH 375 1075 713  HOH HOH B . 
CA 7 HOH 376 1076 1050 HOH HOH B . 
CA 7 HOH 377 1077 1087 HOH HOH B . 
CA 7 HOH 378 1078 700  HOH HOH B . 
CA 7 HOH 379 1079 904  HOH HOH B . 
CA 7 HOH 380 1080 777  HOH HOH B . 
CA 7 HOH 381 1081 866  HOH HOH B . 
CA 7 HOH 382 1082 90   HOH HOH B . 
CA 7 HOH 383 1083 1071 HOH HOH B . 
CA 7 HOH 384 1084 858  HOH HOH B . 
CA 7 HOH 385 1085 472  HOH HOH B . 
CA 7 HOH 386 1086 827  HOH HOH B . 
CA 7 HOH 387 1087 765  HOH HOH B . 
CA 7 HOH 388 1088 792  HOH HOH B . 
CA 7 HOH 389 1089 903  HOH HOH B . 
CA 7 HOH 390 1090 806  HOH HOH B . 
CA 7 HOH 391 1091 729  HOH HOH B . 
CA 7 HOH 392 1092 644  HOH HOH B . 
CA 7 HOH 393 1093 837  HOH HOH B . 
CA 7 HOH 394 1094 651  HOH HOH B . 
CA 7 HOH 395 1095 820  HOH HOH B . 
CA 7 HOH 396 1096 664  HOH HOH B . 
CA 7 HOH 397 1097 645  HOH HOH B . 
CA 7 HOH 398 1098 774  HOH HOH B . 
CA 7 HOH 399 1099 676  HOH HOH B . 
CA 7 HOH 400 1100 672  HOH HOH B . 
CA 7 HOH 401 1101 689  HOH HOH B . 
CA 7 HOH 402 1102 647  HOH HOH B . 
CA 7 HOH 403 1103 1080 HOH HOH B . 
CA 7 HOH 404 1104 902  HOH HOH B . 
CA 7 HOH 405 1105 899  HOH HOH B . 
CA 7 HOH 406 1106 751  HOH HOH B . 
CA 7 HOH 407 1107 227  HOH HOH B . 
CA 7 HOH 408 1108 681  HOH HOH B . 
CA 7 HOH 409 1109 1058 HOH HOH B . 
CA 7 HOH 410 1110 1004 HOH HOH B . 
CA 7 HOH 411 1111 1084 HOH HOH B . 
CA 7 HOH 412 1112 295  HOH HOH B . 
CA 7 HOH 413 1113 714  HOH HOH B . 
CA 7 HOH 414 1114 492  HOH HOH B . 
CA 7 HOH 415 1115 391  HOH HOH B . 
CA 7 HOH 416 1116 838  HOH HOH B . 
CA 7 HOH 417 1117 1063 HOH HOH B . 
CA 7 HOH 418 1118 922  HOH HOH B . 
CA 7 HOH 419 1119 677  HOH HOH B . 
CA 7 HOH 420 1120 290  HOH HOH B . 
CA 7 HOH 421 1121 901  HOH HOH B . 
CA 7 HOH 422 1122 1078 HOH HOH B . 
CA 7 HOH 423 1123 993  HOH HOH B . 
CA 7 HOH 424 1124 1036 HOH HOH B . 
CA 7 HOH 425 1125 458  HOH HOH B . 
CA 7 HOH 426 1126 990  HOH HOH B . 
CA 7 HOH 427 1127 1082 HOH HOH B . 
CA 7 HOH 428 1128 867  HOH HOH B . 
CA 7 HOH 429 1129 702  HOH HOH B . 
CA 7 HOH 430 1130 403  HOH HOH B . 
CA 7 HOH 431 1131 1041 HOH HOH B . 
CA 7 HOH 432 1132 834  HOH HOH B . 
CA 7 HOH 433 1133 198  HOH HOH B . 
CA 7 HOH 434 1134 891  HOH HOH B . 
CA 7 HOH 435 1135 382  HOH HOH B . 
CA 7 HOH 436 1136 327  HOH HOH B . 
CA 7 HOH 437 1137 1074 HOH HOH B . 
CA 7 HOH 438 1138 1035 HOH HOH B . 
CA 7 HOH 439 1139 944  HOH HOH B . 
CA 7 HOH 440 1140 742  HOH HOH B . 
CA 7 HOH 441 1141 952  HOH HOH B . 
CA 7 HOH 442 1142 426  HOH HOH B . 
CA 7 HOH 443 1143 840  HOH HOH B . 
CA 7 HOH 444 1144 674  HOH HOH B . 
CA 7 HOH 445 1145 541  HOH HOH B . 
CA 7 HOH 446 1146 690  HOH HOH B . 
CA 7 HOH 447 1147 413  HOH HOH B . 
CA 7 HOH 448 1148 1048 HOH HOH B . 
CA 7 HOH 449 1149 1091 HOH HOH B . 
CA 7 HOH 450 1150 900  HOH HOH B . 
CA 7 HOH 451 1151 183  HOH HOH B . 
CA 7 HOH 452 1152 910  HOH HOH B . 
CA 7 HOH 453 1153 219  HOH HOH B . 
CA 7 HOH 454 1154 841  HOH HOH B . 
CA 7 HOH 455 1155 445  HOH HOH B . 
CA 7 HOH 456 1156 1053 HOH HOH B . 
CA 7 HOH 457 1157 1059 HOH HOH B . 
CA 7 HOH 458 1158 309  HOH HOH B . 
CA 7 HOH 459 1159 1038 HOH HOH B . 
CA 7 HOH 460 1160 835  HOH HOH B . 
CA 7 HOH 461 1161 1077 HOH HOH B . 
CA 7 HOH 462 1162 963  HOH HOH B . 
CA 7 HOH 463 1163 443  HOH HOH B . 
CA 7 HOH 464 1164 1049 HOH HOH B . 
CA 7 HOH 465 1165 754  HOH HOH B . 
CA 7 HOH 466 1166 642  HOH HOH B . 
CA 7 HOH 467 1167 821  HOH HOH B . 
CA 7 HOH 468 1168 322  HOH HOH B . 
CA 7 HOH 469 1169 715  HOH HOH B . 
CA 7 HOH 470 1170 1034 HOH HOH B . 
CA 7 HOH 471 1171 417  HOH HOH B . 
CA 7 HOH 472 1172 655  HOH HOH B . 
CA 7 HOH 473 1173 1020 HOH HOH B . 
CA 7 HOH 474 1174 436  HOH HOH B . 
CA 7 HOH 475 1175 805  HOH HOH B . 
CA 7 HOH 476 1176 880  HOH HOH B . 
CA 7 HOH 477 1177 354  HOH HOH B . 
CA 7 HOH 478 1178 718  HOH HOH B . 
CA 7 HOH 479 1179 734  HOH HOH B . 
CA 7 HOH 480 1180 809  HOH HOH B . 
CA 7 HOH 481 1181 822  HOH HOH B . 
CA 7 HOH 482 1182 434  HOH HOH B . 
CA 7 HOH 483 1183 708  HOH HOH B . 
CA 7 HOH 484 1184 408  HOH HOH B . 
CA 7 HOH 485 1185 830  HOH HOH B . 
CA 7 HOH 486 1186 414  HOH HOH B . 
CA 7 HOH 487 1187 286  HOH HOH B . 
CA 7 HOH 488 1188 634  HOH HOH B . 
CA 7 HOH 489 1189 253  HOH HOH B . 
CA 7 HOH 490 1190 244  HOH HOH B . 
CA 7 HOH 491 1191 833  HOH HOH B . 
CA 7 HOH 492 1192 1064 HOH HOH B . 
CA 7 HOH 493 1193 730  HOH HOH B . 
CA 7 HOH 494 1194 716  HOH HOH B . 
CA 7 HOH 495 1195 697  HOH HOH B . 
CA 7 HOH 496 1196 337  HOH HOH B . 
CA 7 HOH 497 1197 686  HOH HOH B . 
CA 7 HOH 498 1198 1081 HOH HOH B . 
CA 7 HOH 499 1199 316  HOH HOH B . 
CA 7 HOH 500 1200 906  HOH HOH B . 
CA 7 HOH 501 1201 307  HOH HOH B . 
CA 7 HOH 502 1202 487  HOH HOH B . 
CA 7 HOH 503 1203 548  HOH HOH B . 
CA 7 HOH 504 1204 412  HOH HOH B . 
CA 7 HOH 505 1205 1055 HOH HOH B . 
CA 7 HOH 506 1206 913  HOH HOH B . 
CA 7 HOH 507 1207 699  HOH HOH B . 
CA 7 HOH 508 1208 297  HOH HOH B . 
CA 7 HOH 509 1209 390  HOH HOH B . 
CA 7 HOH 510 1210 908  HOH HOH B . 
CA 7 HOH 511 1211 520  HOH HOH B . 
CA 7 HOH 512 1212 601  HOH HOH B . 
CA 7 HOH 513 1213 829  HOH HOH B . 
CA 7 HOH 514 1214 1073 HOH HOH B . 
CA 7 HOH 515 1215 641  HOH HOH B . 
CA 7 HOH 516 1216 444  HOH HOH B . 
CA 7 HOH 517 1217 673  HOH HOH B . 
CA 7 HOH 518 1218 1085 HOH HOH B . 
CA 7 HOH 519 1219 828  HOH HOH B . 
CA 7 HOH 520 1220 1051 HOH HOH B . 
CA 7 HOH 521 1221 884  HOH HOH B . 
CA 7 HOH 522 1222 471  HOH HOH B . 
CA 7 HOH 523 1223 711  HOH HOH B . 
CA 7 HOH 524 1224 709  HOH HOH B . 
CA 7 HOH 525 1225 943  HOH HOH B . 
CA 7 HOH 526 1226 933  HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LYS 127 ? CG  ? A LYS 96  CG  
2  1 Y 1 A LYS 127 ? CD  ? A LYS 96  CD  
3  1 Y 1 A LYS 127 ? CE  ? A LYS 96  CE  
4  1 Y 1 A LYS 127 ? NZ  ? A LYS 96  NZ  
5  1 Y 1 A LYS 191 ? CG  ? A LYS 160 CG  
6  1 Y 1 A LYS 191 ? CD  ? A LYS 160 CD  
7  1 Y 1 A LYS 191 ? CE  ? A LYS 160 CE  
8  1 Y 1 A LYS 191 ? NZ  ? A LYS 160 NZ  
9  1 Y 1 A LYS 194 ? CG  ? A LYS 163 CG  
10 1 Y 1 A LYS 194 ? CD  ? A LYS 163 CD  
11 1 Y 1 A LYS 194 ? CE  ? A LYS 163 CE  
12 1 Y 1 A LYS 194 ? NZ  ? A LYS 163 NZ  
13 1 Y 1 A LYS 197 ? CG  ? A LYS 166 CG  
14 1 Y 1 A LYS 197 ? CD  ? A LYS 166 CD  
15 1 Y 1 A LYS 197 ? CE  ? A LYS 166 CE  
16 1 Y 1 A LYS 197 ? NZ  ? A LYS 166 NZ  
17 1 Y 1 A LYS 273 ? CG  ? A LYS 242 CG  
18 1 Y 1 A LYS 273 ? CD  ? A LYS 242 CD  
19 1 Y 1 A LYS 273 ? CE  ? A LYS 242 CE  
20 1 Y 1 A LYS 273 ? NZ  ? A LYS 242 NZ  
21 1 Y 1 A LYS 353 ? CG  ? A LYS 322 CG  
22 1 Y 1 A LYS 353 ? CD  ? A LYS 322 CD  
23 1 Y 1 A LYS 353 ? CE  ? A LYS 322 CE  
24 1 Y 1 A LYS 353 ? NZ  ? A LYS 322 NZ  
25 1 Y 1 A LYS 354 ? CG  ? A LYS 323 CG  
26 1 Y 1 A LYS 354 ? CD  ? A LYS 323 CD  
27 1 Y 1 A LYS 354 ? CE  ? A LYS 323 CE  
28 1 Y 1 A LYS 354 ? NZ  ? A LYS 323 NZ  
29 1 Y 1 A LYS 378 ? CG  ? A LYS 347 CG  
30 1 Y 1 A LYS 378 ? CD  ? A LYS 347 CD  
31 1 Y 1 A LYS 378 ? CE  ? A LYS 347 CE  
32 1 Y 1 A LYS 378 ? NZ  ? A LYS 347 NZ  
33 1 Y 1 A LYS 381 ? CG  ? A LYS 350 CG  
34 1 Y 1 A LYS 381 ? CD  ? A LYS 350 CD  
35 1 Y 1 A LYS 381 ? CE  ? A LYS 350 CE  
36 1 Y 1 A LYS 381 ? NZ  ? A LYS 350 NZ  
37 1 Y 1 A LYS 464 ? CG  ? A LYS 433 CG  
38 1 Y 1 A LYS 464 ? CD  ? A LYS 433 CD  
39 1 Y 1 A LYS 464 ? CE  ? A LYS 433 CE  
40 1 Y 1 A LYS 464 ? NZ  ? A LYS 433 NZ  
41 1 Y 1 A LYS 474 ? CG  ? A LYS 443 CG  
42 1 Y 1 A LYS 474 ? CD  ? A LYS 443 CD  
43 1 Y 1 A LYS 474 ? CE  ? A LYS 443 CE  
44 1 Y 1 A LYS 474 ? NZ  ? A LYS 443 NZ  
45 1 Y 1 A GLU 496 ? CG  ? A GLU 465 CG  
46 1 Y 1 A GLU 496 ? CD  ? A GLU 465 CD  
47 1 Y 1 A GLU 496 ? OE1 ? A GLU 465 OE1 
48 1 Y 1 A GLU 496 ? OE2 ? A GLU 465 OE2 
49 1 Y 1 B LYS 197 ? CG  ? B LYS 166 CG  
50 1 Y 1 B LYS 197 ? CD  ? B LYS 166 CD  
51 1 Y 1 B LYS 197 ? CE  ? B LYS 166 CE  
52 1 Y 1 B LYS 197 ? NZ  ? B LYS 166 NZ  
53 1 Y 1 B LYS 198 ? CG  ? B LYS 167 CG  
54 1 Y 1 B LYS 198 ? CD  ? B LYS 167 CD  
55 1 Y 1 B LYS 198 ? CE  ? B LYS 167 CE  
56 1 Y 1 B LYS 198 ? NZ  ? B LYS 167 NZ  
57 1 Y 1 B ASN 203 ? CG  ? B ASN 172 CG  
58 1 Y 1 B ASN 203 ? OD1 ? B ASN 172 OD1 
59 1 Y 1 B ASN 203 ? ND2 ? B ASN 172 ND2 
60 1 Y 1 B LYS 275 ? CG  ? B LYS 244 CG  
61 1 Y 1 B LYS 275 ? CD  ? B LYS 244 CD  
62 1 Y 1 B LYS 275 ? CE  ? B LYS 244 CE  
63 1 Y 1 B LYS 275 ? NZ  ? B LYS 244 NZ  
64 1 Y 1 B LYS 293 ? CG  ? B LYS 262 CG  
65 1 Y 1 B LYS 293 ? CD  ? B LYS 262 CD  
66 1 Y 1 B LYS 293 ? CE  ? B LYS 262 CE  
67 1 Y 1 B LYS 293 ? NZ  ? B LYS 262 NZ  
68 1 Y 1 B LYS 354 ? CG  ? B LYS 323 CG  
69 1 Y 1 B LYS 354 ? CD  ? B LYS 323 CD  
70 1 Y 1 B LYS 354 ? CE  ? B LYS 323 CE  
71 1 Y 1 B LYS 354 ? NZ  ? B LYS 323 NZ  
72 1 Y 1 B LYS 378 ? CG  ? B LYS 347 CG  
73 1 Y 1 B LYS 378 ? CD  ? B LYS 347 CD  
74 1 Y 1 B LYS 378 ? CE  ? B LYS 347 CE  
75 1 Y 1 B LYS 378 ? NZ  ? B LYS 347 NZ  
76 1 Y 1 B LYS 381 ? CG  ? B LYS 350 CG  
77 1 Y 1 B LYS 381 ? CD  ? B LYS 350 CD  
78 1 Y 1 B LYS 381 ? CE  ? B LYS 350 CE  
79 1 Y 1 B LYS 381 ? NZ  ? B LYS 350 NZ  
80 1 Y 1 B LYS 464 ? CG  ? B LYS 433 CG  
81 1 Y 1 B LYS 464 ? CD  ? B LYS 433 CD  
82 1 Y 1 B LYS 464 ? CE  ? B LYS 433 CE  
83 1 Y 1 B LYS 464 ? NZ  ? B LYS 433 NZ  
84 1 Y 1 B LYS 474 ? CG  ? B LYS 443 CG  
85 1 Y 1 B LYS 474 ? CD  ? B LYS 443 CD  
86 1 Y 1 B LYS 474 ? CE  ? B LYS 443 CE  
87 1 Y 1 B LYS 474 ? NZ  ? B LYS 443 NZ  
88 1 Y 1 B GLU 496 ? CG  ? B GLU 465 CG  
89 1 Y 1 B GLU 496 ? CD  ? B GLU 465 CD  
90 1 Y 1 B GLU 496 ? OE1 ? B GLU 465 OE1 
91 1 Y 1 B GLU 496 ? OE2 ? B GLU 465 OE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9HH2 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     95.630 
_cell.length_a_esd                 ? 
_cell.length_b                     96.190 
_cell.length_b_esd                 ? 
_cell.length_c                     106.650 
_cell.length_c_esd                 ? 
_cell.volume                       981035.991 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9HH2 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9HH2 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.24 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          45.06 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M Bis-tris propane pH 7.5, 0.1 M NaBr, 8% PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     80 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-07-07 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.978565 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SOLEIL BEAMLINE PROXIMA 1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.978565 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   'PROXIMA 1' 
_diffrn_source.pdbx_synchrotron_site       SOLEIL 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9HH2 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.58 
_reflns.d_resolution_low                               43.63 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     134822 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.96 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                15.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          21.07 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.58 
_reflns_shell.d_res_low                                     1.636 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             13332 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.693 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               24.38 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9HH2 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.58 
_refine.ls_d_res_low                             43.63 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     134822 
_refine.ls_number_reflns_R_free                  6743 
_refine.ls_number_reflns_R_work                  128107 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.93 
_refine.ls_percent_reflns_R_free                 5.00 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1533 
_refine.ls_R_factor_R_free                       0.1768 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1520 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 17.2788 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1859 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.58 
_refine_hist.d_res_low                        43.63 
_refine_hist.number_atoms_solvent             997 
_refine_hist.number_atoms_total               8569 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        7409 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         163 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0058  ? 7826  ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.8384  ? 10642 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0544  ? 1116  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0094  ? 1376  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 13.5497 ? 2932  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.58 1.60  . . 219 4175 98.85  . . . . 0.2850 . . . . . . . . . . . 0.3196 
'X-RAY DIFFRACTION' 1.60 1.62  . . 224 4239 99.96  . . . . 0.2726 . . . . . . . . . . . 0.3063 
'X-RAY DIFFRACTION' 1.62 1.64  . . 221 4209 99.98  . . . . 0.2589 . . . . . . . . . . . 0.2776 
'X-RAY DIFFRACTION' 1.64 1.66  . . 222 4215 100.00 . . . . 0.2499 . . . . . . . . . . . 0.2700 
'X-RAY DIFFRACTION' 1.66 1.68  . . 223 4233 99.96  . . . . 0.2270 . . . . . . . . . . . 0.2911 
'X-RAY DIFFRACTION' 1.68 1.70  . . 222 4218 100.00 . . . . 0.2144 . . . . . . . . . . . 0.2497 
'X-RAY DIFFRACTION' 1.70 1.73  . . 224 4258 100.00 . . . . 0.1957 . . . . . . . . . . . 0.2410 
'X-RAY DIFFRACTION' 1.73 1.75  . . 223 4234 100.00 . . . . 0.1874 . . . . . . . . . . . 0.2428 
'X-RAY DIFFRACTION' 1.75 1.78  . . 223 4242 100.00 . . . . 0.1771 . . . . . . . . . . . 0.2076 
'X-RAY DIFFRACTION' 1.78 1.81  . . 223 4230 100.00 . . . . 0.1701 . . . . . . . . . . . 0.2269 
'X-RAY DIFFRACTION' 1.81 1.84  . . 224 4253 100.00 . . . . 0.1646 . . . . . . . . . . . 0.2087 
'X-RAY DIFFRACTION' 1.84 1.87  . . 223 4240 100.00 . . . . 0.1582 . . . . . . . . . . . 0.1771 
'X-RAY DIFFRACTION' 1.87 1.91  . . 223 4251 100.00 . . . . 0.1520 . . . . . . . . . . . 0.1800 
'X-RAY DIFFRACTION' 1.91 1.95  . . 223 4224 99.98  . . . . 0.1547 . . . . . . . . . . . 0.1763 
'X-RAY DIFFRACTION' 1.95 1.99  . . 224 4256 100.00 . . . . 0.1515 . . . . . . . . . . . 0.1725 
'X-RAY DIFFRACTION' 1.99 2.04  . . 223 4243 100.00 . . . . 0.1449 . . . . . . . . . . . 0.1881 
'X-RAY DIFFRACTION' 2.04 2.09  . . 225 4277 100.00 . . . . 0.1355 . . . . . . . . . . . 0.1689 
'X-RAY DIFFRACTION' 2.09 2.14  . . 224 4262 100.00 . . . . 0.1354 . . . . . . . . . . . 0.1656 
'X-RAY DIFFRACTION' 2.14 2.21  . . 224 4251 100.00 . . . . 0.1394 . . . . . . . . . . . 0.1856 
'X-RAY DIFFRACTION' 2.21 2.28  . . 226 4283 100.00 . . . . 0.1406 . . . . . . . . . . . 0.1674 
'X-RAY DIFFRACTION' 2.28 2.36  . . 223 4251 100.00 . . . . 0.1422 . . . . . . . . . . . 0.1668 
'X-RAY DIFFRACTION' 2.36 2.45  . . 225 4260 100.00 . . . . 0.1410 . . . . . . . . . . . 0.1860 
'X-RAY DIFFRACTION' 2.45 2.57  . . 225 4287 100.00 . . . . 0.1497 . . . . . . . . . . . 0.1696 
'X-RAY DIFFRACTION' 2.57 2.70  . . 226 4295 100.00 . . . . 0.1450 . . . . . . . . . . . 0.1686 
'X-RAY DIFFRACTION' 2.70 2.87  . . 227 4296 99.96  . . . . 0.1453 . . . . . . . . . . . 0.1680 
'X-RAY DIFFRACTION' 2.87 3.09  . . 226 4311 99.96  . . . . 0.1449 . . . . . . . . . . . 0.1755 
'X-RAY DIFFRACTION' 3.09 3.40  . . 228 4330 100.00 . . . . 0.1368 . . . . . . . . . . . 0.1609 
'X-RAY DIFFRACTION' 3.40 3.89  . . 230 4354 100.00 . . . . 0.1274 . . . . . . . . . . . 0.1503 
'X-RAY DIFFRACTION' 3.89 4.91  . . 230 4384 99.98  . . . . 0.1251 . . . . . . . . . . . 0.1335 
'X-RAY DIFFRACTION' 4.91 43.63 . . 240 4546 99.42  . . . . 0.1927 . . . . . . . . . . . 0.1988 
# 
_struct.entry_id                     9HH2 
_struct.title                        
;Crystal structure of the family S1_19 carrageenan sulfatase ZgCgsA from Zobellia galactanivorans in complex with hybrid a-i-neocarratetraose
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9HH2 
_struct_keywords.text            
'sulfatase, S1_19, carrageenan, covalent intermediate, substrate specificity, complex, oligosaccharide, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A  N N 1 ? 
B  N N 1 ? 
C  N N 2 ? 
D  N N 2 ? 
E  N N 3 ? 
F  N N 4 ? 
G  N N 4 ? 
H  N N 4 ? 
I  N N 5 ? 
J  N N 5 ? 
K  N N 5 ? 
L  N N 5 ? 
M  N N 5 ? 
N  N N 5 ? 
O  N N 6 ? 
P  N N 6 ? 
Q  N N 6 ? 
R  N N 3 ? 
S  N N 4 ? 
T  N N 4 ? 
U  N N 4 ? 
V  N N 5 ? 
W  N N 5 ? 
X  N N 5 ? 
Y  N N 6 ? 
Z  N N 6 ? 
AA N N 6 ? 
BA N N 7 ? 
CA N N 7 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    G0L000_ZOBGA 
_struct_ref.pdbx_db_accession          G0L000 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;QETRPNILVVLCDDLGYADVGFNGSTDILTPELDNLAQNGSIFTSAYVAHPFCGPSRSAILTGRYPHLTGTAYNLFHNSS
EDDKDNMGVPVEETYMSKVLQNAGYYTSAIGKWHLGAAPKFHPNKRGFDDFYGFLGGGHDYFPSEYQKTYKAQKKAGNPN
IRDYVFPMEHNGKPANETEYITDGFSREAIKNIKIAAAKKQPFFIYLAYNAPHVPLQAKAEDVAKFAHIKDKDRRTYAAM
VYAVDRGVGKIVQTLKETKQFDNTLIVFLSDNGGNFNHGANNYPLKGTKGDTWEGGYRVPMFFHWPKKIKKDQRFDFPVS
SLDLYPTFTGLAEAKLPKGKQLDGKNIMDDVLKNTEPYKDEMIYSLRYREGYNDVGARMGDWKITRMGNEPWRLHNITQD
IGEKKNLAGRYPDRLKEMIAKTQEWTKSFVKPLWVYSVKDKELWESGQMPNYEATFEVDKLVDSPYHK
;
_struct_ref.pdbx_align_begin           44 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9HH2 A 13 ? 480 ? G0L000 44 ? 511 ? 44 511 
2 1 9HH2 B 13 ? 480 ? G0L000 44 ? 511 ? 44 511 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9HH2 MET A 1  ? UNP G0L000 ?   ?  'initiating methionine' 32 1  
1 9HH2 GLY A 2  ? UNP G0L000 ?   ?  'expression tag'        33 2  
1 9HH2 SER A 3  ? UNP G0L000 ?   ?  'expression tag'        34 3  
1 9HH2 SER A 4  ? UNP G0L000 ?   ?  'expression tag'        35 4  
1 9HH2 HIS A 5  ? UNP G0L000 ?   ?  'expression tag'        36 5  
1 9HH2 HIS A 6  ? UNP G0L000 ?   ?  'expression tag'        37 6  
1 9HH2 HIS A 7  ? UNP G0L000 ?   ?  'expression tag'        38 7  
1 9HH2 HIS A 8  ? UNP G0L000 ?   ?  'expression tag'        39 8  
1 9HH2 HIS A 9  ? UNP G0L000 ?   ?  'expression tag'        40 9  
1 9HH2 HIS A 10 ? UNP G0L000 ?   ?  'expression tag'        41 10 
1 9HH2 GLY A 11 ? UNP G0L000 ?   ?  'expression tag'        42 11 
1 9HH2 SER A 12 ? UNP G0L000 ?   ?  'expression tag'        43 12 
1 9HH2 OSE A 65 ? UNP G0L000 CYS 96 conflict                96 13 
2 9HH2 MET B 1  ? UNP G0L000 ?   ?  'initiating methionine' 32 14 
2 9HH2 GLY B 2  ? UNP G0L000 ?   ?  'expression tag'        33 15 
2 9HH2 SER B 3  ? UNP G0L000 ?   ?  'expression tag'        34 16 
2 9HH2 SER B 4  ? UNP G0L000 ?   ?  'expression tag'        35 17 
2 9HH2 HIS B 5  ? UNP G0L000 ?   ?  'expression tag'        36 18 
2 9HH2 HIS B 6  ? UNP G0L000 ?   ?  'expression tag'        37 19 
2 9HH2 HIS B 7  ? UNP G0L000 ?   ?  'expression tag'        38 20 
2 9HH2 HIS B 8  ? UNP G0L000 ?   ?  'expression tag'        39 21 
2 9HH2 HIS B 9  ? UNP G0L000 ?   ?  'expression tag'        40 22 
2 9HH2 HIS B 10 ? UNP G0L000 ?   ?  'expression tag'        41 23 
2 9HH2 GLY B 11 ? UNP G0L000 ?   ?  'expression tag'        42 24 
2 9HH2 SER B 12 ? UNP G0L000 ?   ?  'expression tag'        43 25 
2 9HH2 OSE B 65 ? UNP G0L000 CYS 96 conflict                96 26 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 10050 ? 
1 MORE         -63   ? 
1 'SSA (A^2)'  32590 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,AA,BA,CA 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 VAL A 32  ? GLY A 36  ? VAL A 63  GLY A 67  5 ? 5  
HELX_P HELX_P2  AA2 THR A 42  ? ASN A 51  ? THR A 73  ASN A 82  1 ? 10 
HELX_P HELX_P3  AA3 PHE A 64  ? GLY A 75  ? PHE A 95  GLY A 106 1 ? 12 
HELX_P HELX_P4  AA4 TYR A 77  ? GLY A 82  ? TYR A 108 GLY A 113 1 ? 6  
HELX_P HELX_P5  AA5 ASP A 94  ? ASN A 98  ? ASP A 125 ASN A 129 5 ? 5  
HELX_P HELX_P6  AA6 TYR A 107 ? ALA A 115 ? TYR A 138 ALA A 146 1 ? 9  
HELX_P HELX_P7  AA7 ALA A 130 ? ARG A 138 ? ALA A 161 ARG A 169 5 ? 9  
HELX_P HELX_P8  AA8 PHE A 154 ? ALA A 168 ? PHE A 185 ALA A 199 1 ? 15 
HELX_P HELX_P9  AA9 ARG A 174 ? PHE A 178 ? ARG A 205 PHE A 209 5 ? 5  
HELX_P HELX_P10 AB1 TYR A 192 ? LYS A 212 ? TYR A 223 LYS A 243 1 ? 21 
HELX_P HELX_P11 AB2 LYS A 231 ? ALA A 236 ? LYS A 262 ALA A 267 1 ? 6  
HELX_P HELX_P12 AB3 LYS A 237 ? ALA A 239 ? LYS A 268 ALA A 270 5 ? 3  
HELX_P HELX_P13 AB4 ASP A 243 ? THR A 270 ? ASP A 274 THR A 301 1 ? 28 
HELX_P HELX_P14 AB5 TRP A 305 ? TYR A 309 ? TRP A 336 TYR A 340 1 ? 5  
HELX_P HELX_P15 AB6 ASP A 335 ? ALA A 344 ? ASP A 366 ALA A 375 1 ? 10 
HELX_P HELX_P16 AB7 ILE A 359 ? ASN A 366 ? ILE A 390 ASN A 397 1 ? 8  
HELX_P HELX_P17 AB8 TYR A 423 ? LYS A 439 ? TYR A 454 LYS A 470 1 ? 17 
HELX_P HELX_P18 AB9 SER A 449 ? SER A 458 ? SER A 480 SER A 489 1 ? 10 
HELX_P HELX_P19 AC1 ASN A 463 ? PHE A 468 ? ASN A 494 PHE A 499 1 ? 6  
HELX_P HELX_P20 AC2 VAL A 470 ? VAL A 474 ? VAL A 501 VAL A 505 5 ? 5  
HELX_P HELX_P21 AC3 VAL B 32  ? GLY B 36  ? VAL B 63  GLY B 67  5 ? 5  
HELX_P HELX_P22 AC4 THR B 42  ? ASN B 51  ? THR B 73  ASN B 82  1 ? 10 
HELX_P HELX_P23 AC5 PHE B 64  ? GLY B 75  ? PHE B 95  GLY B 106 1 ? 12 
HELX_P HELX_P24 AC6 TYR B 77  ? GLY B 82  ? TYR B 108 GLY B 113 1 ? 6  
HELX_P HELX_P25 AC7 ASP B 94  ? ASN B 98  ? ASP B 125 ASN B 129 5 ? 5  
HELX_P HELX_P26 AC8 TYR B 107 ? ALA B 115 ? TYR B 138 ALA B 146 1 ? 9  
HELX_P HELX_P27 AC9 ALA B 130 ? ARG B 138 ? ALA B 161 ARG B 169 5 ? 9  
HELX_P HELX_P28 AD1 PHE B 154 ? ALA B 168 ? PHE B 185 ALA B 199 1 ? 15 
HELX_P HELX_P29 AD2 ARG B 174 ? PHE B 178 ? ARG B 205 PHE B 209 5 ? 5  
HELX_P HELX_P30 AD3 TYR B 192 ? LYS B 212 ? TYR B 223 LYS B 243 1 ? 21 
HELX_P HELX_P31 AD4 LYS B 231 ? ALA B 236 ? LYS B 262 ALA B 267 1 ? 6  
HELX_P HELX_P32 AD5 LYS B 237 ? ALA B 239 ? LYS B 268 ALA B 270 5 ? 3  
HELX_P HELX_P33 AD6 ASP B 243 ? THR B 270 ? ASP B 274 THR B 301 1 ? 28 
HELX_P HELX_P34 AD7 TRP B 305 ? TYR B 309 ? TRP B 336 TYR B 340 1 ? 5  
HELX_P HELX_P35 AD8 ASP B 335 ? ALA B 344 ? ASP B 366 ALA B 375 1 ? 10 
HELX_P HELX_P36 AD9 ILE B 359 ? ASN B 366 ? ILE B 390 ASN B 397 1 ? 8  
HELX_P HELX_P37 AE1 TYR B 423 ? LYS B 439 ? TYR B 454 LYS B 470 1 ? 17 
HELX_P HELX_P38 AE2 SER B 449 ? SER B 458 ? SER B 480 SER B 489 1 ? 10 
HELX_P HELX_P39 AE3 ASN B 463 ? PHE B 468 ? ASN B 494 PHE B 499 1 ? 6  
HELX_P HELX_P40 AE4 VAL B 470 ? ASP B 475 ? VAL B 501 ASP B 506 1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1  covale both ? A PHE 64  C   ? ? ? 1_555 A OSE 65 N  ? ? A PHE 95  A OSE 96  1_555 ? ? ? ? ? ? ? 1.335 ? ? 
covale2  covale both ? A OSE 65  C   ? ? ? 1_555 A GLY 66 N  ? ? A OSE 96  A GLY 97  1_555 ? ? ? ? ? ? ? 1.331 ? ? 
covale3  covale both ? B PHE 64  C   ? ? ? 1_555 B OSE 65 N  ? ? B PHE 95  B OSE 96  1_555 ? ? ? ? ? ? ? 1.338 ? ? 
covale4  covale both ? B OSE 65  C   ? ? ? 1_555 B GLY 66 N  ? ? B OSE 96  B GLY 97  1_555 ? ? ? ? ? ? ? 1.330 ? ? 
covale5  covale both ? C G4S .   O3  ? ? ? 1_555 C DGS .  C1 ? ? G G4S 1   G DGS 2   1_555 ? ? ? ? ? ? ? 1.450 ? ? 
covale6  covale one  ? C DGS .   O4  ? ? ? 1_555 C GAL .  C1 ? ? G DGS 2   G GAL 3   1_555 ? ? ? ? ? ? ? 1.433 ? ? 
covale7  covale both ? C GAL .   O3  ? ? ? 1_555 C DGS .  C1 ? ? G GAL 3   G DGS 4   1_555 ? ? ? ? ? ? ? 1.444 ? ? 
covale8  covale both ? D G4S .   O3  ? ? ? 1_555 D DGS .  C1 ? ? H G4S 1   H DGS 2   1_555 ? ? ? ? ? ? ? 1.451 ? ? 
covale9  covale one  ? D DGS .   O4  ? ? ? 1_555 D GAL .  C1 ? ? H DGS 2   H GAL 3   1_555 ? ? ? ? ? ? ? 1.434 ? ? 
covale10 covale both ? D GAL .   O3  ? ? ? 1_555 D DGS .  C1 ? ? H GAL 3   H DGS 4   1_555 ? ? ? ? ? ? ? 1.447 ? ? 
metalc1  metalc ?    ? A ASP 25  OD1 ? ? ? 1_555 E CA  .  CA ? ? A ASP 56  A CA  601 1_555 ? ? ? ? ? ? ? 2.288 ? ? 
metalc2  metalc ?    ? A ASP 26  OD1 ? ? ? 1_555 E CA  .  CA ? ? A ASP 57  A CA  601 1_555 ? ? ? ? ? ? ? 2.308 ? ? 
metalc3  metalc ?    ? A OSE 65  O3S ? ? ? 1_555 E CA  .  CA ? ? A OSE 96  A CA  601 1_555 ? ? ? ? ? ? ? 2.332 ? ? 
metalc4  metalc ?    ? A ASP 283 OD1 ? ? ? 1_555 E CA  .  CA ? ? A ASP 314 A CA  601 1_555 ? ? ? ? ? ? ? 2.557 ? ? 
metalc5  metalc ?    ? A ASP 283 OD2 ? ? ? 1_555 E CA  .  CA ? ? A ASP 314 A CA  601 1_555 ? ? ? ? ? ? ? 2.379 ? ? 
metalc6  metalc ?    ? A ASN 284 OD1 ? ? ? 1_555 E CA  .  CA ? ? A ASN 315 A CA  601 1_555 ? ? ? ? ? ? ? 2.397 ? ? 
metalc7  metalc ?    ? B ASP 25  OD1 ? ? ? 1_555 R CA  .  CA ? ? B ASP 56  B CA  601 1_555 ? ? ? ? ? ? ? 2.278 ? ? 
metalc8  metalc ?    ? B ASP 26  OD1 ? ? ? 1_555 R CA  .  CA ? ? B ASP 57  B CA  601 1_555 ? ? ? ? ? ? ? 2.323 ? ? 
metalc9  metalc ?    ? B OSE 65  O3S ? ? ? 1_555 R CA  .  CA ? ? B OSE 96  B CA  601 1_555 ? ? ? ? ? ? ? 2.376 ? ? 
metalc10 metalc ?    ? B ASP 283 OD1 ? ? ? 1_555 R CA  .  CA ? ? B ASP 314 B CA  601 1_555 ? ? ? ? ? ? ? 2.515 ? ? 
metalc11 metalc ?    ? B ASP 283 OD2 ? ? ? 1_555 R CA  .  CA ? ? B ASP 314 B CA  601 1_555 ? ? ? ? ? ? ? 2.363 ? ? 
metalc12 metalc ?    ? B ASN 284 OD1 ? ? ? 1_555 R CA  .  CA ? ? B ASN 315 B CA  601 1_555 ? ? ? ? ? ? ? 2.394 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
covale ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OD1 ? A ASP 25  ? A ASP 56  ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 OD1 ? A ASP 26  ? A ASP 57  ? 1_555 89.9  ? 
2  OD1 ? A ASP 25  ? A ASP 56  ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 O3S ? A OSE 65  ? A OSE 96  ? 1_555 109.8 ? 
3  OD1 ? A ASP 26  ? A ASP 57  ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 O3S ? A OSE 65  ? A OSE 96  ? 1_555 91.8  ? 
4  OD1 ? A ASP 25  ? A ASP 56  ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 OD1 ? A ASP 283 ? A ASP 314 ? 1_555 92.0  ? 
5  OD1 ? A ASP 26  ? A ASP 57  ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 OD1 ? A ASP 283 ? A ASP 314 ? 1_555 108.4 ? 
6  O3S ? A OSE 65  ? A OSE 96  ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 OD1 ? A ASP 283 ? A ASP 314 ? 1_555 150.5 ? 
7  OD1 ? A ASP 25  ? A ASP 56  ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 OD2 ? A ASP 283 ? A ASP 314 ? 1_555 88.9  ? 
8  OD1 ? A ASP 26  ? A ASP 57  ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 OD2 ? A ASP 283 ? A ASP 314 ? 1_555 160.3 ? 
9  O3S ? A OSE 65  ? A OSE 96  ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 OD2 ? A ASP 283 ? A ASP 314 ? 1_555 107.1 ? 
10 OD1 ? A ASP 283 ? A ASP 314 ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 OD2 ? A ASP 283 ? A ASP 314 ? 1_555 52.0  ? 
11 OD1 ? A ASP 25  ? A ASP 56  ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 OD1 ? A ASN 284 ? A ASN 315 ? 1_555 167.7 ? 
12 OD1 ? A ASP 26  ? A ASP 57  ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 OD1 ? A ASN 284 ? A ASN 315 ? 1_555 92.3  ? 
13 O3S ? A OSE 65  ? A OSE 96  ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 OD1 ? A ASN 284 ? A ASN 315 ? 1_555 82.3  ? 
14 OD1 ? A ASP 283 ? A ASP 314 ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 OD1 ? A ASN 284 ? A ASN 315 ? 1_555 75.8  ? 
15 OD2 ? A ASP 283 ? A ASP 314 ? 1_555 CA ? E CA . ? A CA 601 ? 1_555 OD1 ? A ASN 284 ? A ASN 315 ? 1_555 84.9  ? 
16 OD1 ? B ASP 25  ? B ASP 56  ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 OD1 ? B ASP 26  ? B ASP 57  ? 1_555 89.7  ? 
17 OD1 ? B ASP 25  ? B ASP 56  ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 O3S ? B OSE 65  ? B OSE 96  ? 1_555 113.2 ? 
18 OD1 ? B ASP 26  ? B ASP 57  ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 O3S ? B OSE 65  ? B OSE 96  ? 1_555 92.3  ? 
19 OD1 ? B ASP 25  ? B ASP 56  ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 OD1 ? B ASP 283 ? B ASP 314 ? 1_555 90.4  ? 
20 OD1 ? B ASP 26  ? B ASP 57  ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 OD1 ? B ASP 283 ? B ASP 314 ? 1_555 107.2 ? 
21 O3S ? B OSE 65  ? B OSE 96  ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 OD1 ? B ASP 283 ? B ASP 314 ? 1_555 149.7 ? 
22 OD1 ? B ASP 25  ? B ASP 56  ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 OD2 ? B ASP 283 ? B ASP 314 ? 1_555 88.7  ? 
23 OD1 ? B ASP 26  ? B ASP 57  ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 OD2 ? B ASP 283 ? B ASP 314 ? 1_555 160.2 ? 
24 O3S ? B OSE 65  ? B OSE 96  ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 OD2 ? B ASP 283 ? B ASP 314 ? 1_555 106.5 ? 
25 OD1 ? B ASP 283 ? B ASP 314 ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 OD2 ? B ASP 283 ? B ASP 314 ? 1_555 53.1  ? 
26 OD1 ? B ASP 25  ? B ASP 56  ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 OD1 ? B ASN 284 ? B ASN 315 ? 1_555 166.1 ? 
27 OD1 ? B ASP 26  ? B ASP 57  ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 OD1 ? B ASN 284 ? B ASN 315 ? 1_555 91.9  ? 
28 O3S ? B OSE 65  ? B OSE 96  ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 OD1 ? B ASN 284 ? B ASN 315 ? 1_555 80.6  ? 
29 OD1 ? B ASP 283 ? B ASP 314 ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 OD1 ? B ASN 284 ? B ASN 315 ? 1_555 75.9  ? 
30 OD2 ? B ASP 283 ? B ASP 314 ? 1_555 CA ? R CA . ? B CA 601 ? 1_555 OD1 ? B ASN 284 ? B ASN 315 ? 1_555 85.1  ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 OSE A 65 ? . . . . OSE A 96 ? 1_555 . . . . . . . SER 1 OSE Sulfation 'Named protein modification' 
2 OSE B 65 ? . . . . OSE B 96 ? 1_555 . . . . . . . SER 1 OSE Sulfation 'Named protein modification' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ALA 223 A . ? ALA 254 A PRO 224 A ? PRO 255 A 1 -4.42 
2 VAL 226 A . ? VAL 257 A PRO 227 A ? PRO 258 A 1 2.25  
3 TYR 295 A . ? TYR 326 A PRO 296 A ? PRO 327 A 1 3.68  
4 MET 461 A . ? MET 492 A PRO 462 A ? PRO 493 A 1 1.58  
5 ALA 223 B . ? ALA 254 B PRO 224 B ? PRO 255 B 1 -3.36 
6 VAL 226 B . ? VAL 257 B PRO 227 B ? PRO 258 B 1 3.62  
7 TYR 295 B . ? TYR 326 B PRO 296 B ? PRO 327 B 1 2.86  
8 MET 461 B . ? MET 492 B PRO 462 B ? PRO 493 B 1 4.70  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 10 ? 
AA2 ? 3  ? 
AA3 ? 4  ? 
AA4 ? 10 ? 
AA5 ? 3  ? 
AA6 ? 4  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2  ? anti-parallel 
AA1 2 3  ? anti-parallel 
AA1 3 4  ? parallel      
AA1 4 5  ? parallel      
AA1 5 6  ? parallel      
AA1 6 7  ? parallel      
AA1 7 8  ? anti-parallel 
AA1 8 9  ? anti-parallel 
AA1 9 10 ? parallel      
AA2 1 2  ? anti-parallel 
AA2 2 3  ? parallel      
AA3 1 2  ? anti-parallel 
AA3 2 3  ? anti-parallel 
AA3 3 4  ? anti-parallel 
AA4 1 2  ? anti-parallel 
AA4 2 3  ? anti-parallel 
AA4 3 4  ? parallel      
AA4 4 5  ? parallel      
AA4 5 6  ? parallel      
AA4 6 7  ? parallel      
AA4 7 8  ? anti-parallel 
AA4 8 9  ? anti-parallel 
AA4 9 10 ? parallel      
AA5 1 2  ? anti-parallel 
AA5 2 3  ? parallel      
AA6 1 2  ? anti-parallel 
AA6 2 3  ? anti-parallel 
AA6 3 4  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  LYS A 185 ? PRO A 186 ? LYS A 216 PRO A 217 
AA1 2  GLU A 181 ? HIS A 182 ? GLU A 212 HIS A 213 
AA1 3  ASP A 142 ? PHE A 146 ? ASP A 173 PHE A 177 
AA1 4  TYR A 118 ? LYS A 124 ? TYR A 149 LYS A 155 
AA1 5  PHE A 215 ? ALA A 220 ? PHE A 246 ALA A 251 
AA1 6  ASN A 18  ? CYS A 24  ? ASN A 49  CYS A 55  
AA1 7  THR A 276 ? SER A 282 ? THR A 307 SER A 313 
AA1 8  MET A 313 ? HIS A 316 ? MET A 344 HIS A 347 
AA1 9  SER A 53  ? PHE A 55  ? SER A 84  PHE A 86  
AA1 10 GLN A 325 ? PHE A 327 ? GLN A 356 PHE A 358 
AA2 1  ARG A 310 ? VAL A 311 ? ARG A 341 VAL A 342 
AA2 2  ALA A 58  ? TYR A 59  ? ALA A 89  TYR A 90  
AA2 3  VAL A 331 ? SER A 332 ? VAL A 362 SER A 363 
AA3 1  ILE A 375 ? TYR A 380 ? ILE A 406 TYR A 411 
AA3 2  ASN A 385 ? MET A 391 ? ASN A 416 MET A 422 
AA3 3  TRP A 394 ? ARG A 398 ? TRP A 425 ARG A 429 
AA3 4  ARG A 405 ? ASN A 408 ? ARG A 436 ASN A 439 
AA4 1  LYS B 185 ? PRO B 186 ? LYS B 216 PRO B 217 
AA4 2  GLU B 181 ? HIS B 182 ? GLU B 212 HIS B 213 
AA4 3  ASP B 142 ? PHE B 146 ? ASP B 173 PHE B 177 
AA4 4  TYR B 118 ? LYS B 124 ? TYR B 149 LYS B 155 
AA4 5  PHE B 215 ? ALA B 220 ? PHE B 246 ALA B 251 
AA4 6  ASN B 18  ? CYS B 24  ? ASN B 49  CYS B 55  
AA4 7  THR B 276 ? SER B 282 ? THR B 307 SER B 313 
AA4 8  MET B 313 ? HIS B 316 ? MET B 344 HIS B 347 
AA4 9  SER B 53  ? PHE B 55  ? SER B 84  PHE B 86  
AA4 10 GLN B 325 ? PHE B 327 ? GLN B 356 PHE B 358 
AA5 1  ARG B 310 ? VAL B 311 ? ARG B 341 VAL B 342 
AA5 2  ALA B 58  ? TYR B 59  ? ALA B 89  TYR B 90  
AA5 3  VAL B 331 ? SER B 332 ? VAL B 362 SER B 363 
AA6 1  ILE B 375 ? TYR B 380 ? ILE B 406 TYR B 411 
AA6 2  ASN B 385 ? MET B 391 ? ASN B 416 MET B 422 
AA6 3  TRP B 394 ? ARG B 398 ? TRP B 425 ARG B 429 
AA6 4  ARG B 405 ? ASN B 408 ? ARG B 436 ASN B 439 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2  O LYS A 185 ? O LYS A 216 N HIS A 182 ? N HIS A 213 
AA1 2 3  O GLU A 181 ? O GLU A 212 N GLY A 145 ? N GLY A 176 
AA1 3 4  O TYR A 144 ? O TYR A 175 N GLY A 123 ? N GLY A 154 
AA1 4 5  N SER A 120 ? N SER A 151 O TYR A 218 ? O TYR A 249 
AA1 5 6  O ILE A 217 ? O ILE A 248 N VAL A 21  ? N VAL A 52  
AA1 6 7  N VAL A 22  ? N VAL A 53  O VAL A 279 ? O VAL A 310 
AA1 7 8  N ILE A 278 ? N ILE A 309 O HIS A 316 ? O HIS A 347 
AA1 8 9  O MET A 313 ? O MET A 344 N PHE A 55  ? N PHE A 86  
AA1 9 10 N ILE A 54  ? N ILE A 85  O PHE A 327 ? O PHE A 358 
AA2 1 2  O VAL A 311 ? O VAL A 342 N ALA A 58  ? N ALA A 89  
AA2 2 3  N TYR A 59  ? N TYR A 90  O VAL A 331 ? O VAL A 362 
AA3 1 2  N ILE A 375 ? N ILE A 406 O ARG A 390 ? O ARG A 421 
AA3 2 3  N MET A 391 ? N MET A 422 O TRP A 394 ? O TRP A 425 
AA3 3 4  N LYS A 395 ? N LYS A 426 O HIS A 407 ? O HIS A 438 
AA4 1 2  O LYS B 185 ? O LYS B 216 N HIS B 182 ? N HIS B 213 
AA4 2 3  O GLU B 181 ? O GLU B 212 N GLY B 145 ? N GLY B 176 
AA4 3 4  O TYR B 144 ? O TYR B 175 N GLY B 123 ? N GLY B 154 
AA4 4 5  N ILE B 122 ? N ILE B 153 O ALA B 220 ? O ALA B 251 
AA4 5 6  O LEU B 219 ? O LEU B 250 N VAL B 21  ? N VAL B 52  
AA4 6 7  N ASN B 18  ? N ASN B 49  O LEU B 277 ? O LEU B 308 
AA4 7 8  N ILE B 278 ? N ILE B 309 O HIS B 316 ? O HIS B 347 
AA4 8 9  O MET B 313 ? O MET B 344 N PHE B 55  ? N PHE B 86  
AA4 9 10 N ILE B 54  ? N ILE B 85  O PHE B 327 ? O PHE B 358 
AA5 1 2  O VAL B 311 ? O VAL B 342 N ALA B 58  ? N ALA B 89  
AA5 2 3  N TYR B 59  ? N TYR B 90  O VAL B 331 ? O VAL B 362 
AA6 1 2  N ILE B 375 ? N ILE B 406 O ARG B 390 ? O ARG B 421 
AA6 2 3  N ALA B 389 ? N ALA B 420 O ILE B 396 ? O ILE B 427 
AA6 3 4  N LYS B 395 ? N LYS B 426 O HIS B 407 ? O HIS B 438 
# 
_pdbx_entry_details.entry_id                   9HH2 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OE1 
_pdbx_validate_close_contact.auth_asym_id_1   B 
_pdbx_validate_close_contact.auth_comp_id_1   GLN 
_pdbx_validate_close_contact.auth_seq_id_1    442 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   O 
_pdbx_validate_close_contact.auth_asym_id_2   B 
_pdbx_validate_close_contact.auth_comp_id_2   HOH 
_pdbx_validate_close_contact.auth_seq_id_2    701 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 TRP A 156 ? ? -105.91 -79.62 
2  1 TYR A 223 ? ? -38.23  125.76 
3  1 ALA A 251 ? ? -102.94 79.40  
4  1 PRO A 255 ? ? -94.76  36.42  
5  1 LYS A 332 ? ? -36.72  130.65 
6  1 TRP A 348 ? ? -157.76 89.83  
7  1 VAL A 501 ? ? -131.73 -65.51 
8  1 TRP B 156 ? ? -106.53 -78.01 
9  1 ALA B 199 ? ? -69.85  1.63   
10 1 TYR B 223 ? ? -36.78  124.31 
11 1 ALA B 251 ? ? -104.91 77.62  
12 1 PRO B 255 ? ? -95.99  38.16  
13 1 LYS B 332 ? ? -38.89  130.99 
14 1 TRP B 348 ? ? -157.92 89.53  
15 1 VAL B 501 ? ? -129.80 -66.87 
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    A 
_pdbx_validate_planes.auth_seq_id     169 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.097 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      B 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       1226 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.37 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 32  ? A MET 1   
2  1 Y 1 A GLY 33  ? A GLY 2   
3  1 Y 1 A SER 34  ? A SER 3   
4  1 Y 1 A SER 35  ? A SER 4   
5  1 Y 1 A HIS 36  ? A HIS 5   
6  1 Y 1 A HIS 37  ? A HIS 6   
7  1 Y 1 A HIS 38  ? A HIS 7   
8  1 Y 1 A HIS 39  ? A HIS 8   
9  1 Y 1 A HIS 40  ? A HIS 9   
10 1 Y 1 A HIS 41  ? A HIS 10  
11 1 Y 1 A GLY 42  ? A GLY 11  
12 1 Y 1 A SER 43  ? A SER 12  
13 1 Y 1 A GLN 44  ? A GLN 13  
14 1 Y 1 A LYS 511 ? A LYS 480 
15 1 Y 1 B MET 32  ? B MET 1   
16 1 Y 1 B GLY 33  ? B GLY 2   
17 1 Y 1 B SER 34  ? B SER 3   
18 1 Y 1 B SER 35  ? B SER 4   
19 1 Y 1 B HIS 36  ? B HIS 5   
20 1 Y 1 B HIS 37  ? B HIS 6   
21 1 Y 1 B HIS 38  ? B HIS 7   
22 1 Y 1 B HIS 39  ? B HIS 8   
23 1 Y 1 B HIS 40  ? B HIS 9   
24 1 Y 1 B HIS 41  ? B HIS 10  
25 1 Y 1 B GLY 42  ? B GLY 11  
26 1 Y 1 B SER 43  ? B SER 12  
27 1 Y 1 B GLN 44  ? B GLN 13  
28 1 Y 1 B HIS 510 ? B HIS 479 
29 1 Y 1 B LYS 511 ? B LYS 480 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
BR  BR   BR N N 74  
CA  CA   CA N N 75  
CL  CL   CL N N 76  
CYS N    N  N N 77  
CYS CA   C  N R 78  
CYS C    C  N N 79  
CYS O    O  N N 80  
CYS CB   C  N N 81  
CYS SG   S  N N 82  
CYS OXT  O  N N 83  
CYS H    H  N N 84  
CYS H2   H  N N 85  
CYS HA   H  N N 86  
CYS HB2  H  N N 87  
CYS HB3  H  N N 88  
CYS HG   H  N N 89  
CYS HXT  H  N N 90  
DGS C1   C  N S 91  
DGS C2   C  N R 92  
DGS C3   C  N S 93  
DGS C4   C  N S 94  
DGS C5   C  N R 95  
DGS C6   C  N N 96  
DGS O1   O  N N 97  
DGS O2   O  N N 98  
DGS O3   O  N N 99  
DGS O4   O  N N 100 
DGS O5   O  N N 101 
DGS O7   O  N N 102 
DGS O8   O  N N 103 
DGS O9   O  N N 104 
DGS S    S  N N 105 
DGS H1   H  N N 106 
DGS H2   H  N N 107 
DGS H3   H  N N 108 
DGS H4   H  N N 109 
DGS H5   H  N N 110 
DGS H61  H  N N 111 
DGS H62  H  N N 112 
DGS HO1  H  N N 113 
DGS HO4  H  N N 114 
DGS HO7  H  N N 115 
G4S C1   C  N R 116 
G4S C2   C  N R 117 
G4S C3   C  N R 118 
G4S C4   C  N R 119 
G4S C5   C  N R 120 
G4S C6   C  N N 121 
G4S O1   O  N N 122 
G4S O2   O  N N 123 
G4S O3   O  N N 124 
G4S O4   O  N N 125 
G4S O5   O  N N 126 
G4S O6   O  N N 127 
G4S S    S  N N 128 
G4S O7   O  N N 129 
G4S O8   O  N N 130 
G4S O9   O  N N 131 
G4S H1   H  N N 132 
G4S H2   H  N N 133 
G4S H3   H  N N 134 
G4S H4   H  N N 135 
G4S H5   H  N N 136 
G4S H61  H  N N 137 
G4S H62  H  N N 138 
G4S HO1  H  N N 139 
G4S HO2  H  N N 140 
G4S HO3  H  N N 141 
G4S HO6  H  N N 142 
G4S HO4  H  N N 143 
GAL C1   C  N R 144 
GAL C2   C  N R 145 
GAL C3   C  N S 146 
GAL C4   C  N R 147 
GAL C5   C  N R 148 
GAL C6   C  N N 149 
GAL O1   O  N N 150 
GAL O2   O  N N 151 
GAL O3   O  N N 152 
GAL O4   O  N N 153 
GAL O5   O  N N 154 
GAL O6   O  N N 155 
GAL H1   H  N N 156 
GAL H2   H  N N 157 
GAL H3   H  N N 158 
GAL H4   H  N N 159 
GAL H5   H  N N 160 
GAL H61  H  N N 161 
GAL H62  H  N N 162 
GAL HO1  H  N N 163 
GAL HO2  H  N N 164 
GAL HO3  H  N N 165 
GAL HO4  H  N N 166 
GAL HO6  H  N N 167 
GLN N    N  N N 168 
GLN CA   C  N S 169 
GLN C    C  N N 170 
GLN O    O  N N 171 
GLN CB   C  N N 172 
GLN CG   C  N N 173 
GLN CD   C  N N 174 
GLN OE1  O  N N 175 
GLN NE2  N  N N 176 
GLN OXT  O  N N 177 
GLN H    H  N N 178 
GLN H2   H  N N 179 
GLN HA   H  N N 180 
GLN HB2  H  N N 181 
GLN HB3  H  N N 182 
GLN HG2  H  N N 183 
GLN HG3  H  N N 184 
GLN HE21 H  N N 185 
GLN HE22 H  N N 186 
GLN HXT  H  N N 187 
GLU N    N  N N 188 
GLU CA   C  N S 189 
GLU C    C  N N 190 
GLU O    O  N N 191 
GLU CB   C  N N 192 
GLU CG   C  N N 193 
GLU CD   C  N N 194 
GLU OE1  O  N N 195 
GLU OE2  O  N N 196 
GLU OXT  O  N N 197 
GLU H    H  N N 198 
GLU H2   H  N N 199 
GLU HA   H  N N 200 
GLU HB2  H  N N 201 
GLU HB3  H  N N 202 
GLU HG2  H  N N 203 
GLU HG3  H  N N 204 
GLU HE2  H  N N 205 
GLU HXT  H  N N 206 
GLY N    N  N N 207 
GLY CA   C  N N 208 
GLY C    C  N N 209 
GLY O    O  N N 210 
GLY OXT  O  N N 211 
GLY H    H  N N 212 
GLY H2   H  N N 213 
GLY HA2  H  N N 214 
GLY HA3  H  N N 215 
GLY HXT  H  N N 216 
GOL C1   C  N N 217 
GOL O1   O  N N 218 
GOL C2   C  N N 219 
GOL O2   O  N N 220 
GOL C3   C  N N 221 
GOL O3   O  N N 222 
GOL H11  H  N N 223 
GOL H12  H  N N 224 
GOL HO1  H  N N 225 
GOL H2   H  N N 226 
GOL HO2  H  N N 227 
GOL H31  H  N N 228 
GOL H32  H  N N 229 
GOL HO3  H  N N 230 
HIS N    N  N N 231 
HIS CA   C  N S 232 
HIS C    C  N N 233 
HIS O    O  N N 234 
HIS CB   C  N N 235 
HIS CG   C  Y N 236 
HIS ND1  N  Y N 237 
HIS CD2  C  Y N 238 
HIS CE1  C  Y N 239 
HIS NE2  N  Y N 240 
HIS OXT  O  N N 241 
HIS H    H  N N 242 
HIS H2   H  N N 243 
HIS HA   H  N N 244 
HIS HB2  H  N N 245 
HIS HB3  H  N N 246 
HIS HD1  H  N N 247 
HIS HD2  H  N N 248 
HIS HE1  H  N N 249 
HIS HE2  H  N N 250 
HIS HXT  H  N N 251 
HOH O    O  N N 252 
HOH H1   H  N N 253 
HOH H2   H  N N 254 
ILE N    N  N N 255 
ILE CA   C  N S 256 
ILE C    C  N N 257 
ILE O    O  N N 258 
ILE CB   C  N S 259 
ILE CG1  C  N N 260 
ILE CG2  C  N N 261 
ILE CD1  C  N N 262 
ILE OXT  O  N N 263 
ILE H    H  N N 264 
ILE H2   H  N N 265 
ILE HA   H  N N 266 
ILE HB   H  N N 267 
ILE HG12 H  N N 268 
ILE HG13 H  N N 269 
ILE HG21 H  N N 270 
ILE HG22 H  N N 271 
ILE HG23 H  N N 272 
ILE HD11 H  N N 273 
ILE HD12 H  N N 274 
ILE HD13 H  N N 275 
ILE HXT  H  N N 276 
LEU N    N  N N 277 
LEU CA   C  N S 278 
LEU C    C  N N 279 
LEU O    O  N N 280 
LEU CB   C  N N 281 
LEU CG   C  N N 282 
LEU CD1  C  N N 283 
LEU CD2  C  N N 284 
LEU OXT  O  N N 285 
LEU H    H  N N 286 
LEU H2   H  N N 287 
LEU HA   H  N N 288 
LEU HB2  H  N N 289 
LEU HB3  H  N N 290 
LEU HG   H  N N 291 
LEU HD11 H  N N 292 
LEU HD12 H  N N 293 
LEU HD13 H  N N 294 
LEU HD21 H  N N 295 
LEU HD22 H  N N 296 
LEU HD23 H  N N 297 
LEU HXT  H  N N 298 
LYS N    N  N N 299 
LYS CA   C  N S 300 
LYS C    C  N N 301 
LYS O    O  N N 302 
LYS CB   C  N N 303 
LYS CG   C  N N 304 
LYS CD   C  N N 305 
LYS CE   C  N N 306 
LYS NZ   N  N N 307 
LYS OXT  O  N N 308 
LYS H    H  N N 309 
LYS H2   H  N N 310 
LYS HA   H  N N 311 
LYS HB2  H  N N 312 
LYS HB3  H  N N 313 
LYS HG2  H  N N 314 
LYS HG3  H  N N 315 
LYS HD2  H  N N 316 
LYS HD3  H  N N 317 
LYS HE2  H  N N 318 
LYS HE3  H  N N 319 
LYS HZ1  H  N N 320 
LYS HZ2  H  N N 321 
LYS HZ3  H  N N 322 
LYS HXT  H  N N 323 
MET N    N  N N 324 
MET CA   C  N S 325 
MET C    C  N N 326 
MET O    O  N N 327 
MET CB   C  N N 328 
MET CG   C  N N 329 
MET SD   S  N N 330 
MET CE   C  N N 331 
MET OXT  O  N N 332 
MET H    H  N N 333 
MET H2   H  N N 334 
MET HA   H  N N 335 
MET HB2  H  N N 336 
MET HB3  H  N N 337 
MET HG2  H  N N 338 
MET HG3  H  N N 339 
MET HE1  H  N N 340 
MET HE2  H  N N 341 
MET HE3  H  N N 342 
MET HXT  H  N N 343 
OSE N    N  N N 344 
OSE CA   C  N S 345 
OSE CB   C  N N 346 
OSE OG   O  N N 347 
OSE C    C  N N 348 
OSE O    O  N N 349 
OSE S    S  N N 350 
OSE O1S  O  N N 351 
OSE O2S  O  N N 352 
OSE O3S  O  N N 353 
OSE OXT  O  N N 354 
OSE H    H  N N 355 
OSE H2   H  N N 356 
OSE HA   H  N N 357 
OSE HB2  H  N N 358 
OSE HB3  H  N N 359 
OSE H3S  H  N N 360 
OSE HXT  H  N N 361 
PHE N    N  N N 362 
PHE CA   C  N S 363 
PHE C    C  N N 364 
PHE O    O  N N 365 
PHE CB   C  N N 366 
PHE CG   C  Y N 367 
PHE CD1  C  Y N 368 
PHE CD2  C  Y N 369 
PHE CE1  C  Y N 370 
PHE CE2  C  Y N 371 
PHE CZ   C  Y N 372 
PHE OXT  O  N N 373 
PHE H    H  N N 374 
PHE H2   H  N N 375 
PHE HA   H  N N 376 
PHE HB2  H  N N 377 
PHE HB3  H  N N 378 
PHE HD1  H  N N 379 
PHE HD2  H  N N 380 
PHE HE1  H  N N 381 
PHE HE2  H  N N 382 
PHE HZ   H  N N 383 
PHE HXT  H  N N 384 
PRO N    N  N N 385 
PRO CA   C  N S 386 
PRO C    C  N N 387 
PRO O    O  N N 388 
PRO CB   C  N N 389 
PRO CG   C  N N 390 
PRO CD   C  N N 391 
PRO OXT  O  N N 392 
PRO H    H  N N 393 
PRO HA   H  N N 394 
PRO HB2  H  N N 395 
PRO HB3  H  N N 396 
PRO HG2  H  N N 397 
PRO HG3  H  N N 398 
PRO HD2  H  N N 399 
PRO HD3  H  N N 400 
PRO HXT  H  N N 401 
SER N    N  N N 402 
SER CA   C  N S 403 
SER C    C  N N 404 
SER O    O  N N 405 
SER CB   C  N N 406 
SER OG   O  N N 407 
SER OXT  O  N N 408 
SER H    H  N N 409 
SER H2   H  N N 410 
SER HA   H  N N 411 
SER HB2  H  N N 412 
SER HB3  H  N N 413 
SER HG   H  N N 414 
SER HXT  H  N N 415 
THR N    N  N N 416 
THR CA   C  N S 417 
THR C    C  N N 418 
THR O    O  N N 419 
THR CB   C  N R 420 
THR OG1  O  N N 421 
THR CG2  C  N N 422 
THR OXT  O  N N 423 
THR H    H  N N 424 
THR H2   H  N N 425 
THR HA   H  N N 426 
THR HB   H  N N 427 
THR HG1  H  N N 428 
THR HG21 H  N N 429 
THR HG22 H  N N 430 
THR HG23 H  N N 431 
THR HXT  H  N N 432 
TRP N    N  N N 433 
TRP CA   C  N S 434 
TRP C    C  N N 435 
TRP O    O  N N 436 
TRP CB   C  N N 437 
TRP CG   C  Y N 438 
TRP CD1  C  Y N 439 
TRP CD2  C  Y N 440 
TRP NE1  N  Y N 441 
TRP CE2  C  Y N 442 
TRP CE3  C  Y N 443 
TRP CZ2  C  Y N 444 
TRP CZ3  C  Y N 445 
TRP CH2  C  Y N 446 
TRP OXT  O  N N 447 
TRP H    H  N N 448 
TRP H2   H  N N 449 
TRP HA   H  N N 450 
TRP HB2  H  N N 451 
TRP HB3  H  N N 452 
TRP HD1  H  N N 453 
TRP HE1  H  N N 454 
TRP HE3  H  N N 455 
TRP HZ2  H  N N 456 
TRP HZ3  H  N N 457 
TRP HH2  H  N N 458 
TRP HXT  H  N N 459 
TYR N    N  N N 460 
TYR CA   C  N S 461 
TYR C    C  N N 462 
TYR O    O  N N 463 
TYR CB   C  N N 464 
TYR CG   C  Y N 465 
TYR CD1  C  Y N 466 
TYR CD2  C  Y N 467 
TYR CE1  C  Y N 468 
TYR CE2  C  Y N 469 
TYR CZ   C  Y N 470 
TYR OH   O  N N 471 
TYR OXT  O  N N 472 
TYR H    H  N N 473 
TYR H2   H  N N 474 
TYR HA   H  N N 475 
TYR HB2  H  N N 476 
TYR HB3  H  N N 477 
TYR HD1  H  N N 478 
TYR HD2  H  N N 479 
TYR HE1  H  N N 480 
TYR HE2  H  N N 481 
TYR HH   H  N N 482 
TYR HXT  H  N N 483 
VAL N    N  N N 484 
VAL CA   C  N S 485 
VAL C    C  N N 486 
VAL O    O  N N 487 
VAL CB   C  N N 488 
VAL CG1  C  N N 489 
VAL CG2  C  N N 490 
VAL OXT  O  N N 491 
VAL H    H  N N 492 
VAL H2   H  N N 493 
VAL HA   H  N N 494 
VAL HB   H  N N 495 
VAL HG11 H  N N 496 
VAL HG12 H  N N 497 
VAL HG13 H  N N 498 
VAL HG21 H  N N 499 
VAL HG22 H  N N 500 
VAL HG23 H  N N 501 
VAL HXT  H  N N 502 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
DGS C1  C2   sing N N 83  
DGS C1  O1   sing N N 84  
DGS C1  O5   sing N N 85  
DGS C1  H1   sing N N 86  
DGS C2  C3   sing N N 87  
DGS C2  O2   sing N N 88  
DGS C2  H2   sing N N 89  
DGS C3  C4   sing N N 90  
DGS C3  O3   sing N N 91  
DGS C3  H3   sing N N 92  
DGS C4  C5   sing N N 93  
DGS C4  O4   sing N N 94  
DGS C4  H4   sing N N 95  
DGS C5  C6   sing N N 96  
DGS C5  O5   sing N N 97  
DGS C5  H5   sing N N 98  
DGS C6  O3   sing N N 99  
DGS C6  H61  sing N N 100 
DGS C6  H62  sing N N 101 
DGS O1  HO1  sing N N 102 
DGS O2  S    sing N N 103 
DGS O4  HO4  sing N N 104 
DGS O7  S    sing N N 105 
DGS O7  HO7  sing N N 106 
DGS O8  S    doub N N 107 
DGS O9  S    doub N N 108 
G4S C1  C2   sing N N 109 
G4S C1  O1   sing N N 110 
G4S C1  O5   sing N N 111 
G4S C1  H1   sing N N 112 
G4S C2  C3   sing N N 113 
G4S C2  O2   sing N N 114 
G4S C2  H2   sing N N 115 
G4S C3  C4   sing N N 116 
G4S C3  O3   sing N N 117 
G4S C3  H3   sing N N 118 
G4S C4  C5   sing N N 119 
G4S C4  O4   sing N N 120 
G4S C4  H4   sing N N 121 
G4S C5  C6   sing N N 122 
G4S C5  O5   sing N N 123 
G4S C5  H5   sing N N 124 
G4S C6  O6   sing N N 125 
G4S C6  H61  sing N N 126 
G4S C6  H62  sing N N 127 
G4S O1  HO1  sing N N 128 
G4S O2  HO2  sing N N 129 
G4S O3  HO3  sing N N 130 
G4S O4  S    sing N N 131 
G4S O6  HO6  sing N N 132 
G4S S   O7   doub N N 133 
G4S S   O8   doub N N 134 
G4S S   O9   sing N N 135 
G4S HO4 O9   sing N N 136 
GAL C1  C2   sing N N 137 
GAL C1  O1   sing N N 138 
GAL C1  O5   sing N N 139 
GAL C1  H1   sing N N 140 
GAL C2  C3   sing N N 141 
GAL C2  O2   sing N N 142 
GAL C2  H2   sing N N 143 
GAL C3  C4   sing N N 144 
GAL C3  O3   sing N N 145 
GAL C3  H3   sing N N 146 
GAL C4  C5   sing N N 147 
GAL C4  O4   sing N N 148 
GAL C4  H4   sing N N 149 
GAL C5  C6   sing N N 150 
GAL C5  O5   sing N N 151 
GAL C5  H5   sing N N 152 
GAL C6  O6   sing N N 153 
GAL C6  H61  sing N N 154 
GAL C6  H62  sing N N 155 
GAL O1  HO1  sing N N 156 
GAL O2  HO2  sing N N 157 
GAL O3  HO3  sing N N 158 
GAL O4  HO4  sing N N 159 
GAL O6  HO6  sing N N 160 
GLN N   CA   sing N N 161 
GLN N   H    sing N N 162 
GLN N   H2   sing N N 163 
GLN CA  C    sing N N 164 
GLN CA  CB   sing N N 165 
GLN CA  HA   sing N N 166 
GLN C   O    doub N N 167 
GLN C   OXT  sing N N 168 
GLN CB  CG   sing N N 169 
GLN CB  HB2  sing N N 170 
GLN CB  HB3  sing N N 171 
GLN CG  CD   sing N N 172 
GLN CG  HG2  sing N N 173 
GLN CG  HG3  sing N N 174 
GLN CD  OE1  doub N N 175 
GLN CD  NE2  sing N N 176 
GLN NE2 HE21 sing N N 177 
GLN NE2 HE22 sing N N 178 
GLN OXT HXT  sing N N 179 
GLU N   CA   sing N N 180 
GLU N   H    sing N N 181 
GLU N   H2   sing N N 182 
GLU CA  C    sing N N 183 
GLU CA  CB   sing N N 184 
GLU CA  HA   sing N N 185 
GLU C   O    doub N N 186 
GLU C   OXT  sing N N 187 
GLU CB  CG   sing N N 188 
GLU CB  HB2  sing N N 189 
GLU CB  HB3  sing N N 190 
GLU CG  CD   sing N N 191 
GLU CG  HG2  sing N N 192 
GLU CG  HG3  sing N N 193 
GLU CD  OE1  doub N N 194 
GLU CD  OE2  sing N N 195 
GLU OE2 HE2  sing N N 196 
GLU OXT HXT  sing N N 197 
GLY N   CA   sing N N 198 
GLY N   H    sing N N 199 
GLY N   H2   sing N N 200 
GLY CA  C    sing N N 201 
GLY CA  HA2  sing N N 202 
GLY CA  HA3  sing N N 203 
GLY C   O    doub N N 204 
GLY C   OXT  sing N N 205 
GLY OXT HXT  sing N N 206 
GOL C1  O1   sing N N 207 
GOL C1  C2   sing N N 208 
GOL C1  H11  sing N N 209 
GOL C1  H12  sing N N 210 
GOL O1  HO1  sing N N 211 
GOL C2  O2   sing N N 212 
GOL C2  C3   sing N N 213 
GOL C2  H2   sing N N 214 
GOL O2  HO2  sing N N 215 
GOL C3  O3   sing N N 216 
GOL C3  H31  sing N N 217 
GOL C3  H32  sing N N 218 
GOL O3  HO3  sing N N 219 
HIS N   CA   sing N N 220 
HIS N   H    sing N N 221 
HIS N   H2   sing N N 222 
HIS CA  C    sing N N 223 
HIS CA  CB   sing N N 224 
HIS CA  HA   sing N N 225 
HIS C   O    doub N N 226 
HIS C   OXT  sing N N 227 
HIS CB  CG   sing N N 228 
HIS CB  HB2  sing N N 229 
HIS CB  HB3  sing N N 230 
HIS CG  ND1  sing Y N 231 
HIS CG  CD2  doub Y N 232 
HIS ND1 CE1  doub Y N 233 
HIS ND1 HD1  sing N N 234 
HIS CD2 NE2  sing Y N 235 
HIS CD2 HD2  sing N N 236 
HIS CE1 NE2  sing Y N 237 
HIS CE1 HE1  sing N N 238 
HIS NE2 HE2  sing N N 239 
HIS OXT HXT  sing N N 240 
HOH O   H1   sing N N 241 
HOH O   H2   sing N N 242 
ILE N   CA   sing N N 243 
ILE N   H    sing N N 244 
ILE N   H2   sing N N 245 
ILE CA  C    sing N N 246 
ILE CA  CB   sing N N 247 
ILE CA  HA   sing N N 248 
ILE C   O    doub N N 249 
ILE C   OXT  sing N N 250 
ILE CB  CG1  sing N N 251 
ILE CB  CG2  sing N N 252 
ILE CB  HB   sing N N 253 
ILE CG1 CD1  sing N N 254 
ILE CG1 HG12 sing N N 255 
ILE CG1 HG13 sing N N 256 
ILE CG2 HG21 sing N N 257 
ILE CG2 HG22 sing N N 258 
ILE CG2 HG23 sing N N 259 
ILE CD1 HD11 sing N N 260 
ILE CD1 HD12 sing N N 261 
ILE CD1 HD13 sing N N 262 
ILE OXT HXT  sing N N 263 
LEU N   CA   sing N N 264 
LEU N   H    sing N N 265 
LEU N   H2   sing N N 266 
LEU CA  C    sing N N 267 
LEU CA  CB   sing N N 268 
LEU CA  HA   sing N N 269 
LEU C   O    doub N N 270 
LEU C   OXT  sing N N 271 
LEU CB  CG   sing N N 272 
LEU CB  HB2  sing N N 273 
LEU CB  HB3  sing N N 274 
LEU CG  CD1  sing N N 275 
LEU CG  CD2  sing N N 276 
LEU CG  HG   sing N N 277 
LEU CD1 HD11 sing N N 278 
LEU CD1 HD12 sing N N 279 
LEU CD1 HD13 sing N N 280 
LEU CD2 HD21 sing N N 281 
LEU CD2 HD22 sing N N 282 
LEU CD2 HD23 sing N N 283 
LEU OXT HXT  sing N N 284 
LYS N   CA   sing N N 285 
LYS N   H    sing N N 286 
LYS N   H2   sing N N 287 
LYS CA  C    sing N N 288 
LYS CA  CB   sing N N 289 
LYS CA  HA   sing N N 290 
LYS C   O    doub N N 291 
LYS C   OXT  sing N N 292 
LYS CB  CG   sing N N 293 
LYS CB  HB2  sing N N 294 
LYS CB  HB3  sing N N 295 
LYS CG  CD   sing N N 296 
LYS CG  HG2  sing N N 297 
LYS CG  HG3  sing N N 298 
LYS CD  CE   sing N N 299 
LYS CD  HD2  sing N N 300 
LYS CD  HD3  sing N N 301 
LYS CE  NZ   sing N N 302 
LYS CE  HE2  sing N N 303 
LYS CE  HE3  sing N N 304 
LYS NZ  HZ1  sing N N 305 
LYS NZ  HZ2  sing N N 306 
LYS NZ  HZ3  sing N N 307 
LYS OXT HXT  sing N N 308 
MET N   CA   sing N N 309 
MET N   H    sing N N 310 
MET N   H2   sing N N 311 
MET CA  C    sing N N 312 
MET CA  CB   sing N N 313 
MET CA  HA   sing N N 314 
MET C   O    doub N N 315 
MET C   OXT  sing N N 316 
MET CB  CG   sing N N 317 
MET CB  HB2  sing N N 318 
MET CB  HB3  sing N N 319 
MET CG  SD   sing N N 320 
MET CG  HG2  sing N N 321 
MET CG  HG3  sing N N 322 
MET SD  CE   sing N N 323 
MET CE  HE1  sing N N 324 
MET CE  HE2  sing N N 325 
MET CE  HE3  sing N N 326 
MET OXT HXT  sing N N 327 
OSE N   CA   sing N N 328 
OSE N   H    sing N N 329 
OSE N   H2   sing N N 330 
OSE CA  CB   sing N N 331 
OSE CA  C    sing N N 332 
OSE CA  HA   sing N N 333 
OSE CB  OG   sing N N 334 
OSE CB  HB2  sing N N 335 
OSE CB  HB3  sing N N 336 
OSE OG  S    sing N N 337 
OSE C   O    doub N N 338 
OSE C   OXT  sing N N 339 
OSE S   O1S  doub N N 340 
OSE S   O2S  doub N N 341 
OSE S   O3S  sing N N 342 
OSE O3S H3S  sing N N 343 
OSE OXT HXT  sing N N 344 
PHE N   CA   sing N N 345 
PHE N   H    sing N N 346 
PHE N   H2   sing N N 347 
PHE CA  C    sing N N 348 
PHE CA  CB   sing N N 349 
PHE CA  HA   sing N N 350 
PHE C   O    doub N N 351 
PHE C   OXT  sing N N 352 
PHE CB  CG   sing N N 353 
PHE CB  HB2  sing N N 354 
PHE CB  HB3  sing N N 355 
PHE CG  CD1  doub Y N 356 
PHE CG  CD2  sing Y N 357 
PHE CD1 CE1  sing Y N 358 
PHE CD1 HD1  sing N N 359 
PHE CD2 CE2  doub Y N 360 
PHE CD2 HD2  sing N N 361 
PHE CE1 CZ   doub Y N 362 
PHE CE1 HE1  sing N N 363 
PHE CE2 CZ   sing Y N 364 
PHE CE2 HE2  sing N N 365 
PHE CZ  HZ   sing N N 366 
PHE OXT HXT  sing N N 367 
PRO N   CA   sing N N 368 
PRO N   CD   sing N N 369 
PRO N   H    sing N N 370 
PRO CA  C    sing N N 371 
PRO CA  CB   sing N N 372 
PRO CA  HA   sing N N 373 
PRO C   O    doub N N 374 
PRO C   OXT  sing N N 375 
PRO CB  CG   sing N N 376 
PRO CB  HB2  sing N N 377 
PRO CB  HB3  sing N N 378 
PRO CG  CD   sing N N 379 
PRO CG  HG2  sing N N 380 
PRO CG  HG3  sing N N 381 
PRO CD  HD2  sing N N 382 
PRO CD  HD3  sing N N 383 
PRO OXT HXT  sing N N 384 
SER N   CA   sing N N 385 
SER N   H    sing N N 386 
SER N   H2   sing N N 387 
SER CA  C    sing N N 388 
SER CA  CB   sing N N 389 
SER CA  HA   sing N N 390 
SER C   O    doub N N 391 
SER C   OXT  sing N N 392 
SER CB  OG   sing N N 393 
SER CB  HB2  sing N N 394 
SER CB  HB3  sing N N 395 
SER OG  HG   sing N N 396 
SER OXT HXT  sing N N 397 
THR N   CA   sing N N 398 
THR N   H    sing N N 399 
THR N   H2   sing N N 400 
THR CA  C    sing N N 401 
THR CA  CB   sing N N 402 
THR CA  HA   sing N N 403 
THR C   O    doub N N 404 
THR C   OXT  sing N N 405 
THR CB  OG1  sing N N 406 
THR CB  CG2  sing N N 407 
THR CB  HB   sing N N 408 
THR OG1 HG1  sing N N 409 
THR CG2 HG21 sing N N 410 
THR CG2 HG22 sing N N 411 
THR CG2 HG23 sing N N 412 
THR OXT HXT  sing N N 413 
TRP N   CA   sing N N 414 
TRP N   H    sing N N 415 
TRP N   H2   sing N N 416 
TRP CA  C    sing N N 417 
TRP CA  CB   sing N N 418 
TRP CA  HA   sing N N 419 
TRP C   O    doub N N 420 
TRP C   OXT  sing N N 421 
TRP CB  CG   sing N N 422 
TRP CB  HB2  sing N N 423 
TRP CB  HB3  sing N N 424 
TRP CG  CD1  doub Y N 425 
TRP CG  CD2  sing Y N 426 
TRP CD1 NE1  sing Y N 427 
TRP CD1 HD1  sing N N 428 
TRP CD2 CE2  doub Y N 429 
TRP CD2 CE3  sing Y N 430 
TRP NE1 CE2  sing Y N 431 
TRP NE1 HE1  sing N N 432 
TRP CE2 CZ2  sing Y N 433 
TRP CE3 CZ3  doub Y N 434 
TRP CE3 HE3  sing N N 435 
TRP CZ2 CH2  doub Y N 436 
TRP CZ2 HZ2  sing N N 437 
TRP CZ3 CH2  sing Y N 438 
TRP CZ3 HZ3  sing N N 439 
TRP CH2 HH2  sing N N 440 
TRP OXT HXT  sing N N 441 
TYR N   CA   sing N N 442 
TYR N   H    sing N N 443 
TYR N   H2   sing N N 444 
TYR CA  C    sing N N 445 
TYR CA  CB   sing N N 446 
TYR CA  HA   sing N N 447 
TYR C   O    doub N N 448 
TYR C   OXT  sing N N 449 
TYR CB  CG   sing N N 450 
TYR CB  HB2  sing N N 451 
TYR CB  HB3  sing N N 452 
TYR CG  CD1  doub Y N 453 
TYR CG  CD2  sing Y N 454 
TYR CD1 CE1  sing Y N 455 
TYR CD1 HD1  sing N N 456 
TYR CD2 CE2  doub Y N 457 
TYR CD2 HD2  sing N N 458 
TYR CE1 CZ   doub Y N 459 
TYR CE1 HE1  sing N N 460 
TYR CE2 CZ   sing Y N 461 
TYR CE2 HE2  sing N N 462 
TYR CZ  OH   sing N N 463 
TYR OH  HH   sing N N 464 
TYR OXT HXT  sing N N 465 
VAL N   CA   sing N N 466 
VAL N   H    sing N N 467 
VAL N   H2   sing N N 468 
VAL CA  C    sing N N 469 
VAL CA  CB   sing N N 470 
VAL CA  HA   sing N N 471 
VAL C   O    doub N N 472 
VAL C   OXT  sing N N 473 
VAL CB  CG1  sing N N 474 
VAL CB  CG2  sing N N 475 
VAL CB  HB   sing N N 476 
VAL CG1 HG11 sing N N 477 
VAL CG1 HG12 sing N N 478 
VAL CG1 HG13 sing N N 479 
VAL CG2 HG21 sing N N 480 
VAL CG2 HG22 sing N N 481 
VAL CG2 HG23 sing N N 482 
VAL OXT HXT  sing N N 483 
# 
_pdbx_audit_support.funding_organization   'Agence Nationale de la Recherche (ANR)' 
_pdbx_audit_support.country                France 
_pdbx_audit_support.grant_number           'ANR- 22-CE11-0025-01' 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 G4S 1 n 
2 DGS 2 n 
2 GAL 3 n 
2 DGS 4 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9HH2 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.010457 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.010396 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.009376 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
BR 
C  
CA 
CL 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . GLU A  1 14  ? 42.97162 -34.32299 -4.72761  1.000 61.73475 ? 45   GLU A N   1 
ATOM   2    C  CA  . GLU A  1 14  ? 42.32855 -33.08130 -5.14852  1.000 54.33455 ? 45   GLU A CA  1 
ATOM   3    C  C   . GLU A  1 14  ? 42.73048 -31.91750 -4.24135  1.000 52.48535 ? 45   GLU A C   1 
ATOM   4    O  O   . GLU A  1 14  ? 42.43637 -31.91891 -3.04518  1.000 57.31244 ? 45   GLU A O   1 
ATOM   5    C  CB  . GLU A  1 14  ? 40.80476 -33.24306 -5.16028  1.000 54.01127 ? 45   GLU A CB  1 
ATOM   6    C  CG  . GLU A  1 14  ? 40.06405 -32.06031 -5.76276  1.000 44.86965 ? 45   GLU A CG  1 
ATOM   7    C  CD  . GLU A  1 14  ? 40.45240 -31.81201 -7.20938  1.000 37.32993 ? 45   GLU A CD  1 
ATOM   8    O  OE1 . GLU A  1 14  ? 39.87477 -32.46764 -8.10158  1.000 43.40916 ? 45   GLU A OE1 1 
ATOM   9    O  OE2 . GLU A  1 14  ? 41.34595 -30.97198 -7.45188  1.000 37.18477 ? 45   GLU A OE2 1 
ATOM   10   N  N   . THR A  1 15  ? 43.41197 -30.92792 -4.82222  1.000 45.15139 ? 46   THR A N   1 
ATOM   11   C  CA  . THR A  1 15  ? 43.84497 -29.74020 -4.10030  1.000 41.95795 ? 46   THR A CA  1 
ATOM   12   C  C   . THR A  1 15  ? 43.26877 -28.45466 -4.67304  1.000 36.92793 ? 46   THR A C   1 
ATOM   13   O  O   . THR A  1 15  ? 43.51702 -27.37791 -4.11376  1.000 35.27428 ? 46   THR A O   1 
ATOM   14   C  CB  . THR A  1 15  ? 45.37446 -29.63645 -4.10135  1.000 43.81837 ? 46   THR A CB  1 
ATOM   15   O  OG1 . THR A  1 15  ? 45.83819 -29.43371 -5.44361  1.000 45.62497 ? 46   THR A OG1 1 
ATOM   16   C  CG2 . THR A  1 15  ? 45.99335 -30.90636 -3.53808  1.000 49.15182 ? 46   THR A CG2 1 
ATOM   17   N  N   . ARG A  1 16  ? 42.52626 -28.53038 -5.77004  1.000 33.02629 ? 47   ARG A N   1 
ATOM   18   C  CA  . ARG A  1 16  ? 41.97656 -27.32711 -6.36718  1.000 30.80367 ? 47   ARG A CA  1 
ATOM   19   C  C   . ARG A  1 16  ? 40.94130 -26.71256 -5.42863  1.000 26.74316 ? 47   ARG A C   1 
ATOM   20   O  O   . ARG A  1 16  ? 40.18142 -27.43556 -4.77845  1.000 26.76642 ? 47   ARG A O   1 
ATOM   21   C  CB  . ARG A  1 16  ? 41.34372 -27.64406 -7.71975  1.000 29.80374 ? 47   ARG A CB  1 
ATOM   22   C  CG  . ARG A  1 16  ? 42.33420 -28.19627 -8.72681  1.000 31.49591 ? 47   ARG A CG  1 
ATOM   23   C  CD  . ARG A  1 16  ? 41.64254 -28.55655 -10.01985 1.000 29.40748 ? 47   ARG A CD  1 
ATOM   24   N  NE  . ARG A  1 16  ? 40.69638 -29.65324 -9.85563  1.000 27.33385 ? 47   ARG A NE  1 
ATOM   25   C  CZ  . ARG A  1 16  ? 39.80826 -30.00353 -10.77575 1.000 27.92615 ? 47   ARG A CZ  1 
ATOM   26   N  NH1 . ARG A  1 16  ? 39.71830 -29.35700 -11.92919 1.000 26.58795 ? 47   ARG A NH1 1 
ATOM   27   N  NH2 . ARG A  1 16  ? 38.99472 -31.02926 -10.53661 1.000 26.95416 ? 47   ARG A NH2 1 
ATOM   28   N  N   . PRO A  1 17  ? 40.88247 -25.39021 -5.33747  1.000 24.76840 ? 48   PRO A N   1 
ATOM   29   C  CA  . PRO A  1 17  ? 39.98266 -24.76582 -4.36929  1.000 20.24423 ? 48   PRO A CA  1 
ATOM   30   C  C   . PRO A  1 17  ? 38.54254 -24.78030 -4.84105  1.000 21.35923 ? 48   PRO A C   1 
ATOM   31   O  O   . PRO A  1 17  ? 38.25425 -24.73689 -6.03713  1.000 21.23129 ? 48   PRO A O   1 
ATOM   32   C  CB  . PRO A  1 17  ? 40.50925 -23.32948 -4.28640  1.000 20.51774 ? 48   PRO A CB  1 
ATOM   33   C  CG  . PRO A  1 17  ? 41.03848 -23.07192 -5.67122  1.000 24.08838 ? 48   PRO A CG  1 
ATOM   34   C  CD  . PRO A  1 17  ? 41.65856 -24.39225 -6.09460  1.000 24.93577 ? 48   PRO A CD  1 
ATOM   35   N  N   . ASN A  1 18  ? 37.63559 -24.84153 -3.87218  1.000 19.26428 ? 49   ASN A N   1 
ATOM   36   C  CA  . ASN A  1 18  ? 36.25930 -24.45049 -4.13943  1.000 18.35688 ? 49   ASN A CA  1 
ATOM   37   C  C   . ASN A  1 18  ? 36.22111 -22.95669 -4.43808  1.000 17.54319 ? 49   ASN A C   1 
ATOM   38   O  O   . ASN A  1 18  ? 37.08190 -22.19541 -3.99241  1.000 19.38836 ? 49   ASN A O   1 
ATOM   39   C  CB  . ASN A  1 18  ? 35.38103 -24.74955 -2.93374  1.000 17.27389 ? 49   ASN A CB  1 
ATOM   40   C  CG  . ASN A  1 18  ? 35.54653 -26.15705 -2.43639  1.000 20.89184 ? 49   ASN A CG  1 
ATOM   41   O  OD1 . ASN A  1 18  ? 35.33750 -27.11278 -3.17902  1.000 23.45410 ? 49   ASN A OD1 1 
ATOM   42   N  ND2 . ASN A  1 18  ? 35.94326 -26.29815 -1.17679  1.000 21.43595 ? 49   ASN A ND2 1 
ATOM   43   N  N   . ILE A  1 19  ? 35.21865 -22.53507 -5.20676  1.000 17.55585 ? 50   ILE A N   1 
ATOM   44   C  CA  . ILE A  1 19  ? 35.05033 -21.12807 -5.54766  1.000 19.19615 ? 50   ILE A CA  1 
ATOM   45   C  C   . ILE A  1 19  ? 33.60871 -20.74155 -5.25022  1.000 17.15488 ? 50   ILE A C   1 
ATOM   46   O  O   . ILE A  1 19  ? 32.67472 -21.36375 -5.76935  1.000 16.83514 ? 50   ILE A O   1 
ATOM   47   C  CB  . ILE A  1 19  ? 35.40290 -20.84197 -7.01660  1.000 18.67598 ? 50   ILE A CB  1 
ATOM   48   C  CG1 . ILE A  1 19  ? 36.87569 -21.16998 -7.28702  1.000 19.73438 ? 50   ILE A CG1 1 
ATOM   49   C  CG2 . ILE A  1 19  ? 35.10013 -19.36993 -7.37547  1.000 19.39907 ? 50   ILE A CG2 1 
ATOM   50   C  CD1 . ILE A  1 19  ? 37.19886 -21.26703 -8.77057  1.000 18.86396 ? 50   ILE A CD1 1 
ATOM   51   N  N   . LEU A  1 20  ? 33.42895 -19.72055 -4.41800  1.000 16.92611 ? 51   LEU A N   1 
ATOM   52   C  CA  . LEU A  1 20  ? 32.11245 -19.17448 -4.10187  1.000 16.47895 ? 51   LEU A CA  1 
ATOM   53   C  C   . LEU A  1 20  ? 32.09832 -17.71561 -4.51765  1.000 17.62634 ? 51   LEU A C   1 
ATOM   54   O  O   . LEU A  1 20  ? 32.86932 -16.91925 -3.97867  1.000 15.97850 ? 51   LEU A O   1 
ATOM   55   C  CB  . LEU A  1 20  ? 31.80960 -19.29010 -2.60304  1.000 16.34630 ? 51   LEU A CB  1 
ATOM   56   C  CG  . LEU A  1 20  ? 30.54848 -18.55208 -2.13329  1.000 18.55189 ? 51   LEU A CG  1 
ATOM   57   C  CD1 . LEU A  1 20  ? 29.29121 -19.08724 -2.81709  1.000 18.64159 ? 51   LEU A CD1 1 
ATOM   58   C  CD2 . LEU A  1 20  ? 30.38812 -18.62224 -0.60842  1.000 20.32812 ? 51   LEU A CD2 1 
ATOM   59   N  N   . VAL A  1 21  ? 31.23890 -17.36820 -5.47026  1.000 16.73381 ? 52   VAL A N   1 
ATOM   60   C  CA  . VAL A  1 21  ? 31.01249 -15.97432 -5.84025  1.000 16.60790 ? 52   VAL A CA  1 
ATOM   61   C  C   . VAL A  1 21  ? 29.75639 -15.51290 -5.12720  1.000 18.02827 ? 52   VAL A C   1 
ATOM   62   O  O   . VAL A  1 21  ? 28.67938 -16.08162 -5.33160  1.000 18.21724 ? 52   VAL A O   1 
ATOM   63   C  CB  . VAL A  1 21  ? 30.85850 -15.79902 -7.35884  1.000 17.46650 ? 52   VAL A CB  1 
ATOM   64   C  CG1 . VAL A  1 21  ? 30.52096 -14.32927 -7.68880  1.000 17.71302 ? 52   VAL A CG1 1 
ATOM   65   C  CG2 . VAL A  1 21  ? 32.11403 -16.26415 -8.07685  1.000 18.46595 ? 52   VAL A CG2 1 
ATOM   66   N  N   . VAL A  1 22  ? 29.88469 -14.49374 -4.29158  1.000 16.11764 ? 53   VAL A N   1 
ATOM   67   C  CA  . VAL A  1 22  ? 28.73641 -13.88059 -3.64060  1.000 16.62707 ? 53   VAL A CA  1 
ATOM   68   C  C   . VAL A  1 22  ? 28.53829 -12.54761 -4.34050  1.000 14.69092 ? 53   VAL A C   1 
ATOM   69   O  O   . VAL A  1 22  ? 29.33700 -11.61933 -4.17017  1.000 15.78499 ? 53   VAL A O   1 
ATOM   70   C  CB  . VAL A  1 22  ? 28.93584 -13.70528 -2.13107  1.000 17.12835 ? 53   VAL A CB  1 
ATOM   71   C  CG1 . VAL A  1 22  ? 27.68424 -13.08876 -1.51746  1.000 18.20437 ? 53   VAL A CG1 1 
ATOM   72   C  CG2 . VAL A  1 22  ? 29.25824 -15.04668 -1.45199  1.000 16.78934 ? 53   VAL A CG2 1 
ATOM   73   N  N   . LEU A  1 23  ? 27.49947 -12.46664 -5.16347  1.000 15.20744 ? 54   LEU A N   1 
ATOM   74   C  CA  . LEU A  1 23  ? 27.26267 -11.32305 -6.03251  1.000 15.97701 ? 54   LEU A CA  1 
ATOM   75   C  C   . LEU A  1 23  ? 25.98690 -10.63164 -5.57809  1.000 17.03257 ? 54   LEU A C   1 
ATOM   76   O  O   . LEU A  1 23  ? 24.89734 -11.20994 -5.66567  1.000 17.17589 ? 54   LEU A O   1 
ATOM   77   C  CB  . LEU A  1 23  ? 27.15909 -11.77677 -7.48948  1.000 16.03464 ? 54   LEU A CB  1 
ATOM   78   C  CG  . LEU A  1 23  ? 26.90495 -10.66084 -8.50749  1.000 17.02467 ? 54   LEU A CG  1 
ATOM   79   C  CD1 . LEU A  1 23  ? 28.07440 -9.67660  -8.57745  1.000 15.87782 ? 54   LEU A CD1 1 
ATOM   80   C  CD2 . LEU A  1 23  ? 26.61841 -11.25516 -9.89831  1.000 17.99183 ? 54   LEU A CD2 1 
ATOM   81   N  N   . CYS A  1 24  ? 26.12496 -9.41318  -5.06435  1.000 15.57552 ? 55   CYS A N   1 
ATOM   82   C  CA  . CYS A  1 24  ? 24.95755 -8.61496  -4.72657  1.000 15.45256 ? 55   CYS A CA  1 
ATOM   83   C  C   . CYS A  1 24  ? 24.52991 -7.78738  -5.93651  1.000 17.11062 ? 55   CYS A C   1 
ATOM   84   O  O   . CYS A  1 24  ? 25.26931 -7.64645  -6.91192  1.000 18.22382 ? 55   CYS A O   1 
ATOM   85   C  CB  . CYS A  1 24  ? 25.24781 -7.72462  -3.51741  1.000 16.67829 ? 55   CYS A CB  1 
ATOM   86   S  SG  . CYS A  1 24  ? 25.13327 -8.62802  -1.94182  1.000 20.71115 ? 55   CYS A SG  1 
ATOM   87   N  N   . ASP A  1 25  ? 23.32123 -7.22235  -5.85255  1.000 16.46287 ? 56   ASP A N   1 
ATOM   88   C  CA  . ASP A  1 25  ? 22.63274 -6.56145  -6.96459  1.000 15.85271 ? 56   ASP A CA  1 
ATOM   89   C  C   . ASP A  1 25  ? 22.37060 -5.11417  -6.55525  1.000 16.18316 ? 56   ASP A C   1 
ATOM   90   O  O   . ASP A  1 25  ? 21.55634 -4.86032  -5.66278  1.000 17.09365 ? 56   ASP A O   1 
ATOM   91   C  CB  . ASP A  1 25  ? 21.32693 -7.30504  -7.27624  1.000 17.29835 ? 56   ASP A CB  1 
ATOM   92   C  CG  . ASP A  1 25  ? 20.66218 -6.87396  -8.57712  1.000 18.01455 ? 56   ASP A CG  1 
ATOM   93   O  OD1 . ASP A  1 25  ? 21.12740 -5.91718  -9.23764  1.000 19.52217 ? 56   ASP A OD1 1 
ATOM   94   O  OD2 . ASP A  1 25  ? 19.63555 -7.52055  -8.93792  1.000 18.54238 ? 56   ASP A OD2 1 
ATOM   95   N  N   . ASP A  1 26  ? 23.07506 -4.16250  -7.17993  1.000 15.00001 ? 57   ASP A N   1 
ATOM   96   C  CA  . ASP A  1 26  ? 22.92452 -2.72905  -6.88592  1.000 13.36200 ? 57   ASP A CA  1 
ATOM   97   C  C   . ASP A  1 26  ? 23.40211 -2.37408  -5.47777  1.000 14.62123 ? 57   ASP A C   1 
ATOM   98   O  O   . ASP A  1 26  ? 22.83952 -1.48249  -4.82950  1.000 16.19059 ? 57   ASP A O   1 
ATOM   99   C  CB  . ASP A  1 26  ? 21.47373 -2.22630  -7.03510  1.000 14.87105 ? 57   ASP A CB  1 
ATOM   100  C  CG  . ASP A  1 26  ? 20.92390 -2.30460  -8.45485  1.000 17.95952 ? 57   ASP A CG  1 
ATOM   101  O  OD1 . ASP A  1 26  ? 21.63478 -2.71293  -9.38994  1.000 16.27133 ? 57   ASP A OD1 1 
ATOM   102  O  OD2 . ASP A  1 26  ? 19.73784 -1.94301  -8.62915  1.000 18.29745 ? 57   ASP A OD2 1 
ATOM   103  N  N   . LEU A  1 27  ? 24.41990 -3.06398  -4.97411  1.000 15.55972 ? 58   LEU A N   1 
ATOM   104  C  CA  . LEU A  1 27  ? 24.95579 -2.72976  -3.66031  1.000 16.13439 ? 58   LEU A CA  1 
ATOM   105  C  C   . LEU A  1 27  ? 25.84356 -1.48929  -3.76112  1.000 16.73330 ? 58   LEU A C   1 
ATOM   106  O  O   . LEU A  1 27  ? 26.77311 -1.45148  -4.57323  1.000 16.73862 ? 58   LEU A O   1 
ATOM   107  C  CB  . LEU A  1 27  ? 25.73868 -3.91552  -3.09073  1.000 15.81845 ? 58   LEU A CB  1 
ATOM   108  C  CG  . LEU A  1 27  ? 26.47264 -3.62556  -1.77218  1.000 15.98803 ? 58   LEU A CG  1 
ATOM   109  C  CD1 . LEU A  1 27  ? 25.48197 -3.45056  -0.61649  1.000 18.56346 ? 58   LEU A CD1 1 
ATOM   110  C  CD2 . LEU A  1 27  ? 27.44533 -4.76106  -1.48600  1.000 18.15919 ? 58   LEU A CD2 1 
ATOM   111  N  N   . GLY A  1 28  ? 25.55176 -0.48373  -2.92578  1.000 15.57065 ? 59   GLY A N   1 
ATOM   112  C  CA  . GLY A  1 28  ? 26.28448 0.77212   -2.96618  1.000 14.91134 ? 59   GLY A CA  1 
ATOM   113  C  C   . GLY A  1 28  ? 27.68977 0.66595   -2.39374  1.000 14.61326 ? 59   GLY A C   1 
ATOM   114  O  O   . GLY A  1 28  ? 28.00899 -0.21343  -1.59346  1.000 16.30297 ? 59   GLY A O   1 
ATOM   115  N  N   . TYR A  1 29  ? 28.54874 1.59773   -2.83164  1.000 14.57218 ? 60   TYR A N   1 
ATOM   116  C  CA  . TYR A  1 29  ? 29.97892 1.50266   -2.52675  1.000 15.06845 ? 60   TYR A CA  1 
ATOM   117  C  C   . TYR A  1 29  ? 30.25735 1.61851   -1.03873  1.000 17.54403 ? 60   TYR A C   1 
ATOM   118  O  O   . TYR A  1 29  ? 31.19123 0.98342   -0.53065  1.000 17.40238 ? 60   TYR A O   1 
ATOM   119  C  CB  . TYR A  1 29  ? 30.75157 2.59953   -3.26968  1.000 16.45821 ? 60   TYR A CB  1 
ATOM   120  C  CG  . TYR A  1 29  ? 32.22356 2.26966   -3.48336  1.000 16.10450 ? 60   TYR A CG  1 
ATOM   121  C  CD1 . TYR A  1 29  ? 32.60405 1.18295   -4.26467  1.000 16.47147 ? 60   TYR A CD1 1 
ATOM   122  C  CD2 . TYR A  1 29  ? 33.22484 3.07347   -2.93308  1.000 15.59782 ? 60   TYR A CD2 1 
ATOM   123  C  CE1 . TYR A  1 29  ? 33.94954 0.87738   -4.47943  1.000 14.55105 ? 60   TYR A CE1 1 
ATOM   124  C  CE2 . TYR A  1 29  ? 34.56791 2.77832   -3.14038  1.000 18.02795 ? 60   TYR A CE2 1 
ATOM   125  C  CZ  . TYR A  1 29  ? 34.91708 1.69320   -3.92430  1.000 16.60458 ? 60   TYR A CZ  1 
ATOM   126  O  OH  . TYR A  1 29  ? 36.24422 1.40169   -4.13589  1.000 16.28823 ? 60   TYR A OH  1 
ATOM   127  N  N   . ALA A  1 30  ? 29.47395 2.42496   -0.32770  1.000 16.05151 ? 61   ALA A N   1 
ATOM   128  C  CA  . ALA A  1 30  ? 29.68957 2.63530   1.09708   1.000 18.06702 ? 61   ALA A CA  1 
ATOM   129  C  C   . ALA A  1 30  ? 28.72103 1.83929   1.94596   1.000 20.65514 ? 61   ALA A C   1 
ATOM   130  O  O   . ALA A  1 30  ? 28.43126 2.24024   3.07572   1.000 22.05611 ? 61   ALA A O   1 
ATOM   131  C  CB  . ALA A  1 30  ? 29.57097 4.12239   1.43834   1.000 19.73289 ? 61   ALA A CB  1 
ATOM   132  N  N   . ASP A  1 31  ? 28.20102 0.72693   1.43053   1.000 16.98762 ? 62   ASP A N   1 
ATOM   133  C  CA  . ASP A  1 31  ? 27.08511 0.05605   2.07955   1.000 15.78128 ? 62   ASP A CA  1 
ATOM   134  C  C   . ASP A  1 31  ? 27.46842 -1.29285  2.66840   1.000 16.66401 ? 62   ASP A C   1 
ATOM   135  O  O   . ASP A  1 31  ? 26.58318 -2.09400  3.01462   1.000 16.78040 ? 62   ASP A O   1 
ATOM   136  C  CB  . ASP A  1 31  ? 25.92230 -0.05635  1.09676   1.000 15.24571 ? 62   ASP A CB  1 
ATOM   137  C  CG  . ASP A  1 31  ? 25.32905 1.31350   0.77333   1.000 16.54622 ? 62   ASP A CG  1 
ATOM   138  O  OD1 . ASP A  1 31  ? 25.53398 2.24153   1.56979   1.000 17.40736 ? 62   ASP A OD1 1 
ATOM   139  O  OD2 . ASP A  1 31  ? 24.67005 1.47137   -0.27109  1.000 17.10550 ? 62   ASP A OD2 1 
ATOM   140  N  N   . VAL A  1 32  ? 28.77328 -1.55158  2.79748   1.000 16.55415 ? 63   VAL A N   1 
ATOM   141  C  CA  . VAL A  1 32  ? 29.30531 -2.64063  3.61195   1.000 15.71997 ? 63   VAL A CA  1 
ATOM   142  C  C   . VAL A  1 32  ? 30.36611 -2.04539  4.52830   1.000 16.62379 ? 63   VAL A C   1 
ATOM   143  O  O   . VAL A  1 32  ? 31.06024 -1.09183  4.16410   1.000 17.79747 ? 63   VAL A O   1 
ATOM   144  C  CB  . VAL A  1 32  ? 29.88593 -3.79373  2.76284   1.000 16.86049 ? 63   VAL A CB  1 
ATOM   145  C  CG1 . VAL A  1 32  ? 28.75749 -4.55219  2.07651   1.000 19.41305 ? 63   VAL A CG1 1 
ATOM   146  C  CG2 . VAL A  1 32  ? 30.88746 -3.26042  1.72244   1.000 17.24210 ? 63   VAL A CG2 1 
ATOM   147  N  N   . GLY A  1 33  ? 30.48226 -2.61209  5.73214   1.000 16.17448 ? 64   GLY A N   1 
ATOM   148  C  CA  . GLY A  1 33  ? 31.38983 -2.04362  6.71979   1.000 18.67810 ? 64   GLY A CA  1 
ATOM   149  C  C   . GLY A  1 33  ? 32.82907 -1.98795  6.24570   1.000 18.56401 ? 64   GLY A C   1 
ATOM   150  O  O   . GLY A  1 33  ? 33.53013 -0.99137  6.46881   1.000 19.87195 ? 64   GLY A O   1 
ATOM   151  N  N   . PHE A  1 34  ? 33.29310 -3.05226  5.58876   1.000 16.99494 ? 65   PHE A N   1 
ATOM   152  C  CA  . PHE A  1 34  ? 34.69718 -3.08487  5.19140   1.000 17.76269 ? 65   PHE A CA  1 
ATOM   153  C  C   . PHE A  1 34  ? 35.00911 -2.07171  4.10611   1.000 19.17509 ? 65   PHE A C   1 
ATOM   154  O  O   . PHE A  1 34  ? 36.18744 -1.79088  3.86245   1.000 19.62588 ? 65   PHE A O   1 
ATOM   155  C  CB  . PHE A  1 34  ? 35.10587 -4.49540  4.73068   1.000 16.93476 ? 65   PHE A CB  1 
ATOM   156  C  CG  . PHE A  1 34  ? 34.53221 -4.91230  3.39943   1.000 16.38694 ? 65   PHE A CG  1 
ATOM   157  C  CD1 . PHE A  1 34  ? 35.16696 -4.57067  2.20493   1.000 17.25989 ? 65   PHE A CD1 1 
ATOM   158  C  CD2 . PHE A  1 34  ? 33.40058 -5.71361  3.34710   1.000 20.58577 ? 65   PHE A CD2 1 
ATOM   159  C  CE1 . PHE A  1 34  ? 34.63088 -4.97418  0.97497   1.000 18.20911 ? 65   PHE A CE1 1 
ATOM   160  C  CE2 . PHE A  1 34  ? 32.87155 -6.12338  2.12875   1.000 18.07420 ? 65   PHE A CE2 1 
ATOM   161  C  CZ  . PHE A  1 34  ? 33.50467 -5.75994  0.94018   1.000 17.23631 ? 65   PHE A CZ  1 
ATOM   162  N  N   . ASN A  1 35  ? 33.98906 -1.52752  3.43658   1.000 17.81221 ? 66   ASN A N   1 
ATOM   163  C  CA  . ASN A  1 35  ? 34.21406 -0.50600  2.42557   1.000 17.11551 ? 66   ASN A CA  1 
ATOM   164  C  C   . ASN A  1 35  ? 33.72145 0.86676   2.85940   1.000 23.95848 ? 66   ASN A C   1 
ATOM   165  O  O   . ASN A  1 35  ? 33.49666 1.73615   2.00908   1.000 23.06552 ? 66   ASN A O   1 
ATOM   166  C  CB  . ASN A  1 35  ? 33.55096 -0.90720  1.10856   1.000 17.06609 ? 66   ASN A CB  1 
ATOM   167  C  CG  . ASN A  1 35  ? 34.37591 -0.50261  -0.08462  1.000 19.12402 ? 66   ASN A CG  1 
ATOM   168  O  OD1 . ASN A  1 35  ? 35.59316 -0.70172  -0.10042  1.000 22.40577 ? 66   ASN A OD1 1 
ATOM   169  N  ND2 . ASN A  1 35  ? 33.73154 0.09652   -1.07805  1.000 17.84398 ? 66   ASN A ND2 1 
ATOM   170  N  N   . GLY A  1 36  ? 33.52483 1.07307   4.15889   1.000 20.35207 ? 67   GLY A N   1 
ATOM   171  C  CA  . GLY A  1 36  ? 33.30343 2.40241   4.70430   1.000 21.99319 ? 67   GLY A CA  1 
ATOM   172  C  C   . GLY A  1 36  ? 31.95697 2.62946   5.35968   1.000 24.42830 ? 67   GLY A C   1 
ATOM   173  O  O   . GLY A  1 36  ? 31.71302 3.74601   5.83303   1.000 25.82275 ? 67   GLY A O   1 
ATOM   174  N  N   . SER A  1 37  ? 31.05261 1.65495   5.43614   1.000 21.73560 ? 68   SER A N   1 
ATOM   175  C  CA  . SER A  1 37  ? 29.73841 1.95065   5.98787   1.000 21.75602 ? 68   SER A CA  1 
ATOM   176  C  C   . SER A  1 37  ? 29.81184 2.19924   7.48507   1.000 26.87302 ? 68   SER A C   1 
ATOM   177  O  O   . SER A  1 37  ? 30.46845 1.46201   8.22123   1.000 25.67640 ? 68   SER A O   1 
ATOM   178  C  CB  . SER A  1 37  ? 28.76195 0.81377   5.73082   1.000 19.52326 ? 68   SER A CB  1 
ATOM   179  O  OG  . SER A  1 37  ? 27.45504 1.26798   6.04253   1.000 23.32992 ? 68   SER A OG  1 
ATOM   180  N  N   . THR A  1 38  ? 29.10005 3.23311   7.93712   1.000 25.28955 ? 69   THR A N   1 
ATOM   181  C  CA  . THR A  1 38  ? 28.97300 3.49468   9.36085   1.000 30.78617 ? 69   THR A CA  1 
ATOM   182  C  C   . THR A  1 38  ? 27.59723 3.16063   9.91358   1.000 29.12719 ? 69   THR A C   1 
ATOM   183  O  O   . THR A  1 38  ? 27.46047 3.02933   11.13264  1.000 34.26639 ? 69   THR A O   1 
ATOM   184  C  CB  . THR A  1 38  ? 29.28803 4.96535   9.66914   1.000 31.15081 ? 69   THR A CB  1 
ATOM   185  O  OG1 . THR A  1 38  ? 28.39903 5.80630   8.92827   1.000 32.45815 ? 69   THR A OG1 1 
ATOM   186  C  CG2 . THR A  1 38  ? 30.72337 5.29394   9.27360   1.000 38.55079 ? 69   THR A CG2 1 
ATOM   187  N  N   . ASP A  1 39  ? 26.58361 3.00203   9.06185   1.000 21.31380 ? 70   ASP A N   1 
ATOM   188  C  CA  . ASP A  1 39  ? 25.24483 2.69829   9.54239   1.000 21.13466 ? 70   ASP A CA  1 
ATOM   189  C  C   . ASP A  1 39  ? 24.74679 1.31446   9.16741   1.000 23.16466 ? 70   ASP A C   1 
ATOM   190  O  O   . ASP A  1 39  ? 23.88812 0.77639   9.86769   1.000 23.43595 ? 70   ASP A O   1 
ATOM   191  C  CB  . ASP A  1 39  ? 24.22739 3.74603   9.05031   1.000 24.29451 ? 70   ASP A CB  1 
ATOM   192  C  CG  . ASP A  1 39  ? 24.20203 3.90281   7.53494   1.000 26.98978 ? 70   ASP A CG  1 
ATOM   193  O  OD1 . ASP A  1 39  ? 25.12989 3.42590   6.84603   1.000 22.45305 ? 70   ASP A OD1 1 
ATOM   194  O  OD2 . ASP A  1 39  ? 23.23919 4.52296   7.03306   1.000 25.28065 ? 70   ASP A OD2 1 
ATOM   195  N  N   . ILE A  1 40  ? 25.25248 0.71274   8.09872   1.000 20.52829 ? 71   ILE A N   1 
ATOM   196  C  CA  . ILE A  1 40  ? 24.84930 -0.64206  7.74288   1.000 18.79831 ? 71   ILE A CA  1 
ATOM   197  C  C   . ILE A  1 40  ? 25.81765 -1.61830  8.38478   1.000 20.30026 ? 71   ILE A C   1 
ATOM   198  O  O   . ILE A  1 40  ? 27.03781 -1.45994  8.26746   1.000 22.84446 ? 71   ILE A O   1 
ATOM   199  C  CB  . ILE A  1 40  ? 24.80230 -0.82761  6.22128   1.000 18.51000 ? 71   ILE A CB  1 
ATOM   200  C  CG1 . ILE A  1 40  ? 23.83856 0.18505   5.61124   1.000 20.26534 ? 71   ILE A CG1 1 
ATOM   201  C  CG2 . ILE A  1 40  ? 24.37128 -2.26733  5.87119   1.000 20.29177 ? 71   ILE A CG2 1 
ATOM   202  C  CD1 . ILE A  1 40  ? 23.60912 -0.02466  4.12587   1.000 20.62696 ? 71   ILE A CD1 1 
ATOM   203  N  N   . LEU A  1 41  ? 25.27527 -2.61972  9.07884   1.000 17.80119 ? 72   LEU A N   1 
ATOM   204  C  CA  . LEU A  1 41  ? 26.07429 -3.60148  9.79763   1.000 20.57985 ? 72   LEU A CA  1 
ATOM   205  C  C   . LEU A  1 41  ? 26.24939 -4.83482  8.92364   1.000 19.82899 ? 72   LEU A C   1 
ATOM   206  O  O   . LEU A  1 41  ? 25.26137 -5.48637  8.56235   1.000 19.90938 ? 72   LEU A O   1 
ATOM   207  C  CB  . LEU A  1 41  ? 25.39607 -3.97815  11.11725  1.000 23.10912 ? 72   LEU A CB  1 
ATOM   208  C  CG  . LEU A  1 41  ? 25.02617 -2.79612  12.00862  1.000 28.46575 ? 72   LEU A CG  1 
ATOM   209  C  CD1 . LEU A  1 41  ? 24.33554 -3.29187  13.27517  1.000 28.84863 ? 72   LEU A CD1 1 
ATOM   210  C  CD2 . LEU A  1 41  ? 26.24840 -1.97395  12.35029  1.000 31.84636 ? 72   LEU A CD2 1 
ATOM   211  N  N   . THR A  1 42  ? 27.50298 -5.16331  8.59886   1.000 18.36753 ? 73   THR A N   1 
ATOM   212  C  CA  . THR A  1 42  ? 27.83040 -6.36501  7.82767   1.000 18.02262 ? 73   THR A CA  1 
ATOM   213  C  C   . THR A  1 42  ? 28.98056 -7.10480  8.50288   1.000 18.26819 ? 73   THR A C   1 
ATOM   214  O  O   . THR A  1 42  ? 30.06661 -7.25654  7.93675   1.000 17.79789 ? 73   THR A O   1 
ATOM   215  C  CB  . THR A  1 42  ? 28.17831 -6.02258  6.37649   1.000 19.81991 ? 73   THR A CB  1 
ATOM   216  O  OG1 . THR A  1 42  ? 29.31098 -5.14454  6.33460   1.000 17.63627 ? 73   THR A OG1 1 
ATOM   217  C  CG2 . THR A  1 42  ? 26.99066 -5.36070  5.66851   1.000 20.41060 ? 73   THR A CG2 1 
ATOM   218  N  N   . PRO A  1 43  ? 28.76901 -7.59260  9.72741   1.000 16.96492 ? 74   PRO A N   1 
ATOM   219  C  CA  . PRO A  1 43  ? 29.89376 -8.17975  10.47505  1.000 18.54583 ? 74   PRO A CA  1 
ATOM   220  C  C   . PRO A  1 43  ? 30.47539 -9.43827  9.84512   1.000 18.33695 ? 74   PRO A C   1 
ATOM   221  O  O   . PRO A  1 43  ? 31.69207 -9.65359  9.94300   1.000 19.39155 ? 74   PRO A O   1 
ATOM   222  C  CB  . PRO A  1 43  ? 29.27382 -8.46796  11.85125  1.000 18.91481 ? 74   PRO A CB  1 
ATOM   223  C  CG  . PRO A  1 43  ? 27.81104 -8.62955  11.57210  1.000 19.84592 ? 74   PRO A CG  1 
ATOM   224  C  CD  . PRO A  1 43  ? 27.53379 -7.57035  10.53307  1.000 18.45179 ? 74   PRO A CD  1 
ATOM   225  N  N   . GLU A  1 44  ? 29.65447 -10.27831 9.21053   1.000 17.55173 ? 75   GLU A N   1 
ATOM   226  C  CA  . GLU A  1 44  ? 30.18475 -11.50879 8.62229   1.000 19.85134 ? 75   GLU A CA  1 
ATOM   227  C  C   . GLU A  1 44  ? 31.00586 -11.21114 7.37645   1.000 18.92566 ? 75   GLU A C   1 
ATOM   228  O  O   . GLU A  1 44  ? 32.10192 -11.76416 7.19219   1.000 17.86542 ? 75   GLU A O   1 
ATOM   229  C  CB  . GLU A  1 44  ? 29.03904 -12.46676 8.30846   1.000 19.17753 ? 75   GLU A CB  1 
ATOM   230  C  CG  . GLU A  1 44  ? 28.17241 -12.78472 9.52302   1.000 20.78833 ? 75   GLU A CG  1 
ATOM   231  C  CD  . GLU A  1 44  ? 28.84361 -13.74486 10.49292  1.000 29.85434 ? 75   GLU A CD  1 
ATOM   232  O  OE1 . GLU A  1 44  ? 29.91133 -14.30403 10.15830  1.000 23.98611 ? 75   GLU A OE1 1 
ATOM   233  O  OE2 . GLU A  1 44  ? 28.28981 -13.95539 11.59337  1.000 30.72426 ? 75   GLU A OE2 1 
ATOM   234  N  N   . LEU A  1 45  ? 30.49489 -10.33035 6.51204   1.000 17.61818 ? 76   LEU A N   1 
ATOM   235  C  CA  . LEU A  1 45  ? 31.27062 -9.91373  5.35023   1.000 16.78454 ? 76   LEU A CA  1 
ATOM   236  C  C   . LEU A  1 45  ? 32.54797 -9.20863  5.77665   1.000 19.24124 ? 76   LEU A C   1 
ATOM   237  O  O   . LEU A  1 45  ? 33.62032 -9.43503  5.19748   1.000 18.24029 ? 76   LEU A O   1 
ATOM   238  C  CB  . LEU A  1 45  ? 30.42537 -8.99741  4.46339   1.000 16.15243 ? 76   LEU A CB  1 
ATOM   239  C  CG  . LEU A  1 45  ? 29.31084 -9.70899  3.68946   1.000 18.29960 ? 76   LEU A CG  1 
ATOM   240  C  CD1 . LEU A  1 45  ? 28.32535 -8.68272  3.15155   1.000 19.72382 ? 76   LEU A CD1 1 
ATOM   241  C  CD2 . LEU A  1 45  ? 29.90044 -10.51733 2.54220   1.000 19.75750 ? 76   LEU A CD2 1 
ATOM   242  N  N   . ASP A  1 46  ? 32.45006 -8.34382  6.78644   1.000 18.25520 ? 77   ASP A N   1 
ATOM   243  C  CA  . ASP A  1 46  ? 33.63286 -7.63118  7.25560   1.000 17.25924 ? 77   ASP A CA  1 
ATOM   244  C  C   . ASP A  1 46  ? 34.68286 -8.59848  7.77854   1.000 18.49214 ? 77   ASP A C   1 
ATOM   245  O  O   . ASP A  1 46  ? 35.88436 -8.40036  7.56097   1.000 18.81860 ? 77   ASP A O   1 
ATOM   246  C  CB  . ASP A  1 46  ? 33.26042 -6.64871  8.35899   1.000 17.82745 ? 77   ASP A CB  1 
ATOM   247  C  CG  . ASP A  1 46  ? 32.47049 -5.45853  7.85317   1.000 21.61605 ? 77   ASP A CG  1 
ATOM   248  O  OD1 . ASP A  1 46  ? 32.14645 -5.38235  6.63994   1.000 18.32105 ? 77   ASP A OD1 1 
ATOM   249  O  OD2 . ASP A  1 46  ? 32.17729 -4.59066  8.69731   1.000 20.59628 ? 77   ASP A OD2 1 
ATOM   250  N  N   . ASN A  1 47  ? 34.25228 -9.63437  8.50011   1.000 18.23208 ? 78   ASN A N   1 
ATOM   251  C  CA  . ASN A  1 47  ? 35.22432 -10.58137 9.02973   1.000 21.47092 ? 78   ASN A CA  1 
ATOM   252  C  C   . ASN A  1 47  ? 35.94687 -11.30557 7.90410   1.000 20.44026 ? 78   ASN A C   1 
ATOM   253  O  O   . ASN A  1 47  ? 37.16911 -11.47555 7.95327   1.000 19.67759 ? 78   ASN A O   1 
ATOM   254  C  CB  . ASN A  1 47  ? 34.55099 -11.57597 9.97141   1.000 21.23081 ? 78   ASN A CB  1 
ATOM   255  C  CG  . ASN A  1 47  ? 35.56607 -12.43514 10.71935  1.000 28.99907 ? 78   ASN A CG  1 
ATOM   256  O  OD1 . ASN A  1 47  ? 35.70256 -13.62311 10.45213  1.000 37.13711 ? 78   ASN A OD1 1 
ATOM   257  N  ND2 . ASN A  1 47  ? 36.29751 -11.81892 11.63914  1.000 34.15650 ? 78   ASN A ND2 1 
ATOM   258  N  N   . LEU A  1 48  ? 35.21571 -11.73027 6.87022   1.000 17.89514 ? 79   LEU A N   1 
ATOM   259  C  CA  . LEU A  1 48  ? 35.89246 -12.34826 5.73224   1.000 16.12626 ? 79   LEU A CA  1 
ATOM   260  C  C   . LEU A  1 48  ? 36.85466 -11.36688 5.07732   1.000 18.65633 ? 79   LEU A C   1 
ATOM   261  O  O   . LEU A  1 48  ? 38.00660 -11.71026 4.78619   1.000 18.36633 ? 79   LEU A O   1 
ATOM   262  C  CB  . LEU A  1 48  ? 34.87785 -12.86022 4.70908   1.000 17.14865 ? 79   LEU A CB  1 
ATOM   263  C  CG  . LEU A  1 48  ? 33.99470 -14.03359 5.12639   1.000 18.52680 ? 79   LEU A CG  1 
ATOM   264  C  CD1 . LEU A  1 48  ? 32.98695 -14.33669 4.02648   1.000 20.06336 ? 79   LEU A CD1 1 
ATOM   265  C  CD2 . LEU A  1 48  ? 34.83618 -15.27753 5.47612   1.000 20.83941 ? 79   LEU A CD2 1 
ATOM   266  N  N   . ALA A  1 49  ? 36.39566 -10.13648 4.83353   1.000 17.70256 ? 80   ALA A N   1 
ATOM   267  C  CA  . ALA A  1 49  ? 37.24326 -9.13738  4.19014   1.000 17.38062 ? 80   ALA A CA  1 
ATOM   268  C  C   . ALA A  1 49  ? 38.51342 -8.88259  4.99688   1.000 18.38378 ? 80   ALA A C   1 
ATOM   269  O  O   . ALA A  1 49  ? 39.61416 -8.81433  4.43385   1.000 19.17809 ? 80   ALA A O   1 
ATOM   270  C  CB  . ALA A  1 49  ? 36.45916 -7.83590  3.99491   1.000 16.46380 ? 80   ALA A CB  1 
ATOM   271  N  N   . GLN A  1 50  ? 38.38107 -8.75579  6.32029   1.000 17.58963 ? 81   GLN A N   1 
ATOM   272  C  CA  . GLN A  1 50  ? 39.54372 -8.50144  7.16820   1.000 19.00392 ? 81   GLN A CA  1 
ATOM   273  C  C   . GLN A  1 50  ? 40.50675 -9.67470  7.18652   1.000 21.28683 ? 81   GLN A C   1 
ATOM   274  O  O   . GLN A  1 50  ? 41.69945 -9.48129  7.46034   1.000 22.02769 ? 81   GLN A O   1 
ATOM   275  C  CB  . GLN A  1 50  ? 39.08785 -8.18675  8.58874   1.000 22.62551 ? 81   GLN A CB  1 
ATOM   276  C  CG  . GLN A  1 50  ? 38.33904 -6.87780  8.70749   1.000 29.66710 ? 81   GLN A CG  1 
ATOM   277  C  CD  . GLN A  1 50  ? 37.48715 -6.80984  9.96463   1.000 31.75610 ? 81   GLN A CD  1 
ATOM   278  O  OE1 . GLN A  1 50  ? 37.54127 -7.70438  10.81279  1.000 38.32272 ? 81   GLN A OE1 1 
ATOM   279  N  NE2 . GLN A  1 50  ? 36.68843 -5.75551  10.08405  1.000 29.44235 ? 81   GLN A NE2 1 
ATOM   280  N  N   . ASN A  1 51  ? 40.01997 -10.87985 6.89860   1.000 19.86395 ? 82   ASN A N   1 
ATOM   281  C  CA  . ASN A  1 51  ? 40.85240 -12.07480 6.85929   1.000 20.68880 ? 82   ASN A CA  1 
ATOM   282  C  C   . ASN A  1 51  ? 41.29104 -12.42853 5.44880   1.000 20.19789 ? 82   ASN A C   1 
ATOM   283  O  O   . ASN A  1 51  ? 41.77696 -13.53930 5.21886   1.000 20.68422 ? 82   ASN A O   1 
ATOM   284  C  CB  . ASN A  1 51  ? 40.12514 -13.24973 7.51406   1.000 20.50269 ? 82   ASN A CB  1 
ATOM   285  C  CG  . ASN A  1 51  ? 40.20635 -13.18973 9.03082   1.000 30.70645 ? 82   ASN A CG  1 
ATOM   286  O  OD1 . ASN A  1 51  ? 41.27301 -13.39360 9.60492   1.000 35.00983 ? 82   ASN A OD1 1 
ATOM   287  N  ND2 . ASN A  1 51  ? 39.09208 -12.89137 9.68023   1.000 30.41052 ? 82   ASN A ND2 1 
ATOM   288  N  N   . GLY A  1 52  ? 41.15857 -11.49322 4.51314   1.000 17.86210 ? 83   GLY A N   1 
ATOM   289  C  CA  . GLY A  1 52  ? 41.64041 -11.68109 3.14960   1.000 18.41314 ? 83   GLY A CA  1 
ATOM   290  C  C   . GLY A  1 52  ? 42.04982 -10.36423 2.54895   1.000 20.50755 ? 83   GLY A C   1 
ATOM   291  O  O   . GLY A  1 52  ? 42.61216 -9.50653  3.24183   1.000 20.47162 ? 83   GLY A O   1 
ATOM   292  N  N   . SER A  1 53  ? 41.73633 -10.17127 1.26960   1.000 18.22402 ? 84   SER A N   1 
ATOM   293  C  CA  . SER A  1 53  ? 42.19766 -9.01466  0.50975   1.000 18.49008 ? 84   SER A CA  1 
ATOM   294  C  C   . SER A  1 53  ? 41.00672 -8.15895  0.09043   1.000 17.40704 ? 84   SER A C   1 
ATOM   295  O  O   . SER A  1 53  ? 40.11664 -8.64290  -0.61741  1.000 18.36336 ? 84   SER A O   1 
ATOM   296  C  CB  . SER A  1 53  ? 42.98662 -9.47064  -0.72274  1.000 21.53657 ? 84   SER A CB  1 
ATOM   297  O  OG  . SER A  1 53  ? 43.46674 -8.36344  -1.45823  1.000 25.42094 ? 84   SER A OG  1 
ATOM   298  N  N   . ILE A  1 54  ? 40.99742 -6.89801  0.52848   1.000 16.44411 ? 85   ILE A N   1 
ATOM   299  C  CA  . ILE A  1 54  ? 40.00812 -5.90894  0.10575   1.000 16.80331 ? 85   ILE A CA  1 
ATOM   300  C  C   . ILE A  1 54  ? 40.53175 -5.19919  -1.13415  1.000 17.80968 ? 85   ILE A C   1 
ATOM   301  O  O   . ILE A  1 54  ? 41.66271 -4.70388  -1.14647  1.000 18.48105 ? 85   ILE A O   1 
ATOM   302  C  CB  . ILE A  1 54  ? 39.73230 -4.90178  1.23488   1.000 18.77131 ? 85   ILE A CB  1 
ATOM   303  C  CG1 . ILE A  1 54  ? 39.07075 -5.60790  2.41275   1.000 18.48762 ? 85   ILE A CG1 1 
ATOM   304  C  CG2 . ILE A  1 54  ? 38.88679 -3.72365  0.73210   1.000 21.23876 ? 85   ILE A CG2 1 
ATOM   305  C  CD1 . ILE A  1 54  ? 38.99305 -4.74309  3.64996   1.000 20.06580 ? 85   ILE A CD1 1 
ATOM   306  N  N   . PHE A  1 55  ? 39.70894 -5.12610  -2.17733  1.000 15.40479 ? 86   PHE A N   1 
ATOM   307  C  CA  . PHE A  1 55  ? 40.09950 -4.47956  -3.42387  1.000 15.75582 ? 86   PHE A CA  1 
ATOM   308  C  C   . PHE A  1 55  ? 39.51430 -3.07245  -3.42350  1.000 16.00171 ? 86   PHE A C   1 
ATOM   309  O  O   . PHE A  1 55  ? 38.29238 -2.90264  -3.48019  1.000 17.24067 ? 86   PHE A O   1 
ATOM   310  C  CB  . PHE A  1 55  ? 39.61859 -5.28506  -4.62931  1.000 15.82406 ? 86   PHE A CB  1 
ATOM   311  C  CG  . PHE A  1 55  ? 40.34019 -6.58909  -4.78849  1.000 16.37691 ? 86   PHE A CG  1 
ATOM   312  C  CD1 . PHE A  1 55  ? 40.02675 -7.67175  -3.97510  1.000 17.22032 ? 86   PHE A CD1 1 
ATOM   313  C  CD2 . PHE A  1 55  ? 41.35403 -6.72663  -5.72496  1.000 19.78672 ? 86   PHE A CD2 1 
ATOM   314  C  CE1 . PHE A  1 55  ? 40.70386 -8.88163  -4.10561  1.000 19.19117 ? 86   PHE A CE1 1 
ATOM   315  C  CE2 . PHE A  1 55  ? 42.03249 -7.92286  -5.85746  1.000 20.22238 ? 86   PHE A CE2 1 
ATOM   316  C  CZ  . PHE A  1 55  ? 41.71053 -9.00402  -5.04828  1.000 20.60029 ? 86   PHE A CZ  1 
ATOM   317  N  N   . THR A  1 56  ? 40.38329 -2.06610  -3.34951  1.000 17.57473 ? 87   THR A N   1 
ATOM   318  C  CA  . THR A  1 56  ? 39.90838 -0.69676  -3.22743  1.000 15.99953 ? 87   THR A CA  1 
ATOM   319  C  C   . THR A  1 56  ? 39.62513 -0.03875  -4.56997  1.000 15.93636 ? 87   THR A C   1 
ATOM   320  O  O   . THR A  1 56  ? 39.03113 1.04683   -4.59173  1.000 17.86504 ? 87   THR A O   1 
ATOM   321  C  CB  . THR A  1 56  ? 40.91117 0.14399   -2.43286  1.000 19.00741 ? 87   THR A CB  1 
ATOM   322  O  OG1 . THR A  1 56  ? 42.19668 0.08713   -3.06500  1.000 18.87750 ? 87   THR A OG1 1 
ATOM   323  C  CG2 . THR A  1 56  ? 41.02874 -0.41013  -1.03902  1.000 19.77308 ? 87   THR A CG2 1 
ATOM   324  N  N   . SER A  1 57  ? 40.01882 -0.67464  -5.68156  1.000 16.38950 ? 88   SER A N   1 
ATOM   325  C  CA  . SER A  1 57  ? 39.73051 -0.18743  -7.03400  1.000 16.19286 ? 88   SER A CA  1 
ATOM   326  C  C   . SER A  1 57  ? 39.23992 -1.35337  -7.89122  1.000 16.72316 ? 88   SER A C   1 
ATOM   327  O  O   . SER A  1 57  ? 39.86693 -1.74376  -8.87539  1.000 17.16258 ? 88   SER A O   1 
ATOM   328  C  CB  . SER A  1 57  ? 40.95134 0.46414   -7.69438  1.000 16.41316 ? 88   SER A CB  1 
ATOM   329  O  OG  . SER A  1 57  ? 41.16244 1.77881   -7.20328  1.000 17.92703 ? 88   SER A OG  1 
ATOM   330  N  N   . ALA A  1 58  ? 38.09327 -1.90982  -7.51183  1.000 14.93493 ? 89   ALA A N   1 
ATOM   331  C  CA  . ALA A  1 58  ? 37.48362 -3.02930  -8.22726  1.000 14.17662 ? 89   ALA A CA  1 
ATOM   332  C  C   . ALA A  1 58  ? 36.36936 -2.50870  -9.12847  1.000 15.23268 ? 89   ALA A C   1 
ATOM   333  O  O   . ALA A  1 58  ? 35.51735 -1.73780  -8.68102  1.000 16.36636 ? 89   ALA A O   1 
ATOM   334  C  CB  . ALA A  1 58  ? 36.93988 -4.06392  -7.23804  1.000 16.37860 ? 89   ALA A CB  1 
ATOM   335  N  N   . TYR A  1 59  ? 36.36287 -2.94397  -10.39323 1.000 14.89016 ? 90   TYR A N   1 
ATOM   336  C  CA  . TYR A  1 59  ? 35.40683 -2.44985  -11.37850 1.000 13.89857 ? 90   TYR A CA  1 
ATOM   337  C  C   . TYR A  1 59  ? 34.62826 -3.58828  -12.00433 1.000 13.66743 ? 90   TYR A C   1 
ATOM   338  O  O   . TYR A  1 59  ? 35.19387 -4.64820  -12.29702 1.000 16.58223 ? 90   TYR A O   1 
ATOM   339  C  CB  . TYR A  1 59  ? 36.10088 -1.69590  -12.50297 1.000 14.71741 ? 90   TYR A CB  1 
ATOM   340  C  CG  . TYR A  1 59  ? 36.78905 -0.44615  -12.02613 1.000 14.84638 ? 90   TYR A CG  1 
ATOM   341  C  CD1 . TYR A  1 59  ? 36.07567 0.73799   -11.88173 1.000 14.78374 ? 90   TYR A CD1 1 
ATOM   342  C  CD2 . TYR A  1 59  ? 38.13760 -0.46156  -11.66146 1.000 16.08851 ? 90   TYR A CD2 1 
ATOM   343  C  CE1 . TYR A  1 59  ? 36.67957 1.89111   -11.42312 1.000 15.27454 ? 90   TYR A CE1 1 
ATOM   344  C  CE2 . TYR A  1 59  ? 38.76652 0.70342   -11.21731 1.000 18.17620 ? 90   TYR A CE2 1 
ATOM   345  C  CZ  . TYR A  1 59  ? 38.01843 1.87519   -11.10580 1.000 17.58797 ? 90   TYR A CZ  1 
ATOM   346  O  OH  . TYR A  1 59  ? 38.58131 3.04291   -10.66584 1.000 16.53671 ? 90   TYR A OH  1 
ATOM   347  N  N   . VAL A  1 60  ? 33.33824 -3.34740  -12.25436 1.000 13.63919 ? 91   VAL A N   1 
ATOM   348  C  CA  . VAL A  1 60  ? 32.56930 -4.22654  -13.12485 1.000 14.79448 ? 91   VAL A CA  1 
ATOM   349  C  C   . VAL A  1 60  ? 32.61878 -3.68667  -14.55042 1.000 14.85195 ? 91   VAL A C   1 
ATOM   350  O  O   . VAL A  1 60  ? 32.94996 -2.52452  -14.79714 1.000 16.18110 ? 91   VAL A O   1 
ATOM   351  C  CB  . VAL A  1 60  ? 31.11847 -4.39925  -12.62694 1.000 16.71335 ? 91   VAL A CB  1 
ATOM   352  C  CG1 . VAL A  1 60  ? 31.12087 -5.22062  -11.33625 1.000 15.55882 ? 91   VAL A CG1 1 
ATOM   353  C  CG2 . VAL A  1 60  ? 30.44901 -3.03554  -12.40075 1.000 14.17304 ? 91   VAL A CG2 1 
ATOM   354  N  N   . ALA A  1 61  ? 32.28721 -4.55430  -15.51053 1.000 16.40297 ? 92   ALA A N   1 
ATOM   355  C  CA  . ALA A  1 61  ? 32.48245 -4.21179  -16.91432 1.000 15.09495 ? 92   ALA A CA  1 
ATOM   356  C  C   . ALA A  1 61  ? 31.37488 -3.33550  -17.48594 1.000 18.17792 ? 92   ALA A C   1 
ATOM   357  O  O   . ALA A  1 61  ? 31.49201 -2.88569  -18.62835 1.000 16.21821 ? 92   ALA A O   1 
ATOM   358  C  CB  . ALA A  1 61  ? 32.59876 -5.49101  -17.74491 1.000 15.83042 ? 92   ALA A CB  1 
ATOM   359  N  N   . HIS A  1 62  ? 30.30766 -3.08426  -16.73311 1.000 16.70882 ? 93   HIS A N   1 
ATOM   360  C  CA  . HIS A  1 62  ? 29.21577 -2.23924  -17.19079 1.000 16.01565 ? 93   HIS A CA  1 
ATOM   361  C  C   . HIS A  1 62  ? 28.48626 -1.73956  -15.96534 1.000 14.96478 ? 93   HIS A C   1 
ATOM   362  O  O   . HIS A  1 62  ? 28.39305 -2.48001  -14.97651 1.000 15.62109 ? 93   HIS A O   1 
ATOM   363  C  CB  . HIS A  1 62  ? 28.24590 -3.01970  -18.08902 1.000 16.51767 ? 93   HIS A CB  1 
ATOM   364  C  CG  . HIS A  1 62  ? 27.42015 -2.14790  -18.97767 1.000 15.35629 ? 93   HIS A CG  1 
ATOM   365  N  ND1 . HIS A  1 62  ? 27.95402 -1.48026  -20.06054 1.000 16.66906 ? 93   HIS A ND1 1 
ATOM   366  C  CD2 . HIS A  1 62  ? 26.11387 -1.79192  -18.92214 1.000 16.02828 ? 93   HIS A CD2 1 
ATOM   367  C  CE1 . HIS A  1 62  ? 27.00170 -0.78423  -20.65764 1.000 16.44947 ? 93   HIS A CE1 1 
ATOM   368  N  NE2 . HIS A  1 62  ? 25.87468 -0.96011  -19.98923 1.000 17.78317 ? 93   HIS A NE2 1 
ATOM   369  N  N   . PRO A  1 63  ? 27.94196 -0.50735  -15.99542 1.000 15.51537 ? 94   PRO A N   1 
ATOM   370  C  CA  . PRO A  1 63  ? 27.33234 0.05865   -14.77978 1.000 15.43568 ? 94   PRO A CA  1 
ATOM   371  C  C   . PRO A  1 63  ? 25.89400 -0.37760  -14.51882 1.000 15.07639 ? 94   PRO A C   1 
ATOM   372  O  O   . PRO A  1 63  ? 25.20997 0.25308   -13.71175 1.000 15.77946 ? 94   PRO A O   1 
ATOM   373  C  CB  . PRO A  1 63  ? 27.42417 1.57093   -15.02225 1.000 15.39248 ? 94   PRO A CB  1 
ATOM   374  C  CG  . PRO A  1 63  ? 27.34144 1.70748   -16.52885 1.000 17.20708 ? 94   PRO A CG  1 
ATOM   375  C  CD  . PRO A  1 63  ? 28.10742 0.51228   -17.05563 1.000 14.85262 ? 94   PRO A CD  1 
ATOM   376  N  N   . PHE A  1 64  ? 25.40580 -1.42713  -15.17316 1.000 15.43847 ? 95   PHE A N   1 
ATOM   377  C  CA  . PHE A  1 64  ? 24.15772 -2.04096  -14.73368 1.000 15.71938 ? 95   PHE A CA  1 
ATOM   378  C  C   . PHE A  1 64  ? 24.08274 -3.52840  -15.11921 1.000 18.72598 ? 95   PHE A C   1 
ATOM   379  O  O   . PHE A  1 64  ? 24.88644 -4.01938  -15.91456 1.000 18.78022 ? 95   PHE A O   1 
ATOM   380  C  CB  . PHE A  1 64  ? 22.92529 -1.24911  -15.23723 1.000 18.51968 ? 95   PHE A CB  1 
ATOM   381  C  CG  . PHE A  1 64  ? 22.80292 -1.11220  -16.74463 1.000 16.89179 ? 95   PHE A CG  1 
ATOM   382  C  CD1 . PHE A  1 64  ? 22.29635 -2.15272  -17.50884 1.000 17.32725 ? 95   PHE A CD1 1 
ATOM   383  C  CD2 . PHE A  1 64  ? 23.10930 0.09057   -17.37081 1.000 17.83392 ? 95   PHE A CD2 1 
ATOM   384  C  CE1 . PHE A  1 64  ? 22.14502 -2.02118  -18.88850 1.000 17.52917 ? 95   PHE A CE1 1 
ATOM   385  C  CE2 . PHE A  1 64  ? 22.95814 0.23797   -18.74226 1.000 18.08518 ? 95   PHE A CE2 1 
ATOM   386  C  CZ  . PHE A  1 64  ? 22.47142 -0.82590  -19.50393 1.000 16.24652 ? 95   PHE A CZ  1 
HETATM 387  N  N   . OSE A  1 65  ? 23.08804 -4.21647  -14.55293 1.000 22.54747 ? 96   OSE A N   1 
HETATM 388  C  CA  . OSE A  1 65  ? 23.15778 -5.67736  -14.26427 1.000 21.88466 ? 96   OSE A CA  1 
HETATM 389  C  CB  . OSE A  1 65  ? 21.94276 -6.14954  -13.53687 1.000 27.07811 ? 96   OSE A CB  1 
HETATM 390  O  OG  . OSE A  1 65  ? 20.90241 -5.52768  -14.22745 1.000 36.46294 ? 96   OSE A OG  1 
HETATM 391  C  C   . OSE A  1 65  ? 23.32673 -6.56513  -15.49405 1.000 17.12954 ? 96   OSE A C   1 
HETATM 392  O  O   . OSE A  1 65  ? 24.22757 -7.39646  -15.43160 1.000 17.56898 ? 96   OSE A O   1 
HETATM 393  S  S   . OSE A  1 65  ? 20.20298 -4.44270  -13.39259 1.000 30.51176 ? 96   OSE A S   1 
HETATM 394  O  O1S . OSE A  1 65  ? 19.74573 -3.45064  -14.34372 1.000 38.05547 ? 96   OSE A O1S 1 
HETATM 395  O  O2S . OSE A  1 65  ? 19.12859 -5.18882  -12.76742 1.000 35.76986 ? 96   OSE A O2S 1 
HETATM 396  O  O3S . OSE A  1 65  ? 21.16948 -3.93431  -12.45509 1.000 28.39784 ? 96   OSE A O3S 1 
ATOM   397  N  N   . GLY A  1 66  ? 22.42326 -6.51679  -16.47086 1.000 18.21203 ? 97   GLY A N   1 
ATOM   398  C  CA  . GLY A  1 66  ? 22.44703 -7.53171  -17.51697 1.000 18.33425 ? 97   GLY A CA  1 
ATOM   399  C  C   . GLY A  1 66  ? 23.80387 -7.62132  -18.19767 1.000 17.32782 ? 97   GLY A C   1 
ATOM   400  O  O   . GLY A  1 66  ? 24.41804 -8.69178  -18.27683 1.000 17.97760 ? 97   GLY A O   1 
ATOM   401  N  N   . PRO A  1 67  ? 24.28309 -6.48250  -18.69274 1.000 16.59932 ? 98   PRO A N   1 
ATOM   402  C  CA  . PRO A  1 67  ? 25.61417 -6.47719  -19.32170 1.000 14.71649 ? 98   PRO A CA  1 
ATOM   403  C  C   . PRO A  1 67  ? 26.74617 -6.79389  -18.36201 1.000 18.02978 ? 98   PRO A C   1 
ATOM   404  O  O   . PRO A  1 67  ? 27.72753 -7.43688  -18.75561 1.000 16.58886 ? 98   PRO A O   1 
ATOM   405  C  CB  . PRO A  1 67  ? 25.72398 -5.05443  -19.88364 1.000 16.77917 ? 98   PRO A CB  1 
ATOM   406  C  CG  . PRO A  1 67  ? 24.29653 -4.63333  -20.09686 1.000 18.24056 ? 98   PRO A CG  1 
ATOM   407  C  CD  . PRO A  1 67  ? 23.54661 -5.22801  -18.92940 1.000 17.34976 ? 98   PRO A CD  1 
ATOM   408  N  N   . SER A  1 68  ? 26.63746 -6.36851  -17.10458 1.000 15.94782 ? 99   SER A N   1 
ATOM   409  C  CA  . SER A  1 68  ? 27.66107 -6.72273  -16.13053 1.000 14.61429 ? 99   SER A CA  1 
ATOM   410  C  C   . SER A  1 68  ? 27.68633 -8.22631  -15.86776 1.000 16.83995 ? 99   SER A C   1 
ATOM   411  O  O   . SER A  1 68  ? 28.76078 -8.83563  -15.80854 1.000 15.65790 ? 99   SER A O   1 
ATOM   412  C  CB  . SER A  1 68  ? 27.41730 -5.95538  -14.83411 1.000 15.52687 ? 99   SER A CB  1 
ATOM   413  O  OG  . SER A  1 68  ? 28.30392 -6.40096  -13.82268 1.000 15.44588 ? 99   SER A OG  1 
ATOM   414  N  N   . ARG A  1 69  ? 26.51169 -8.84445  -15.71248 1.000 16.22339 ? 100  ARG A N   1 
ATOM   415  C  CA  . ARG A  1 69  ? 26.45987 -10.27421 -15.44693 1.000 15.77928 ? 100  ARG A CA  1 
ATOM   416  C  C   . ARG A  1 69  ? 26.89064 -11.06736 -16.67349 1.000 14.71969 ? 100  ARG A C   1 
ATOM   417  O  O   . ARG A  1 69  ? 27.57554 -12.08951 -16.55109 1.000 16.94693 ? 100  ARG A O   1 
ATOM   418  C  CB  . ARG A  1 69  ? 25.04696 -10.64863 -14.99480 1.000 15.99786 ? 100  ARG A CB  1 
ATOM   419  C  CG  . ARG A  1 69  ? 24.72940 -10.05606 -13.62284 1.000 18.30460 ? 100  ARG A CG  1 
ATOM   420  C  CD  . ARG A  1 69  ? 23.23726 -9.82827  -13.36442 1.000 15.01393 ? 100  ARG A CD  1 
ATOM   421  N  NE  . ARG A  1 69  ? 23.08157 -9.08021  -12.12089 1.000 15.51755 ? 100  ARG A NE  1 
ATOM   422  C  CZ  . ARG A  1 69  ? 23.04631 -9.64381  -10.91923 1.000 15.67206 ? 100  ARG A CZ  1 
ATOM   423  N  NH1 . ARG A  1 69  ? 23.04188 -10.96523 -10.76988 1.000 15.75737 ? 100  ARG A NH1 1 
ATOM   424  N  NH2 . ARG A  1 69  ? 22.99770 -8.86555  -9.84035  1.000 16.74726 ? 100  ARG A NH2 1 
ATOM   425  N  N   . SER A  1 70  ? 26.53378 -10.57779 -17.86433 1.000 15.55405 ? 101  SER A N   1 
ATOM   426  C  CA  . SER A  1 70  ? 27.02759 -11.18250 -19.09664 1.000 17.75052 ? 101  SER A CA  1 
ATOM   427  C  C   . SER A  1 70  ? 28.54622 -11.18855 -19.11324 1.000 17.73076 ? 101  SER A C   1 
ATOM   428  O  O   . SER A  1 70  ? 29.16831 -12.21053 -19.43413 1.000 18.07583 ? 101  SER A O   1 
ATOM   429  C  CB  . SER A  1 70  ? 26.47602 -10.41792 -20.30334 1.000 17.69121 ? 101  SER A CB  1 
ATOM   430  O  OG  . SER A  1 70  ? 27.05572 -10.86719 -21.52411 1.000 24.21019 ? 101  SER A OG  1 
ATOM   431  N  N   . ALA A  1 71  ? 29.15641 -10.06787 -18.70566 1.000 16.81907 ? 102  ALA A N   1 
ATOM   432  C  CA  . ALA A  1 71  ? 30.61289 -9.96871  -18.68875 1.000 17.77401 ? 102  ALA A CA  1 
ATOM   433  C  C   . ALA A  1 71  ? 31.22459 -10.91010 -17.66157 1.000 16.50304 ? 102  ALA A C   1 
ATOM   434  O  O   . ALA A  1 71  ? 32.27896 -11.49722 -17.90410 1.000 17.66673 ? 102  ALA A O   1 
ATOM   435  C  CB  . ALA A  1 71  ? 31.03489 -8.53119  -18.40030 1.000 17.44524 ? 102  ALA A CB  1 
ATOM   436  N  N   . ILE A  1 72  ? 30.59269 -11.04751 -16.49335 1.000 17.24924 ? 103  ILE A N   1 
ATOM   437  C  CA  . ILE A  1 72  ? 31.14231 -11.93470 -15.47331 1.000 16.73297 ? 103  ILE A CA  1 
ATOM   438  C  C   . ILE A  1 72  ? 31.19406 -13.36448 -15.98968 1.000 17.39059 ? 103  ILE A C   1 
ATOM   439  O  O   . ILE A  1 72  ? 32.22272 -14.03721 -15.88825 1.000 18.21376 ? 103  ILE A O   1 
ATOM   440  C  CB  . ILE A  1 72  ? 30.32997 -11.83693 -14.16883 1.000 15.17645 ? 103  ILE A CB  1 
ATOM   441  C  CG1 . ILE A  1 72  ? 30.64627 -10.52094 -13.45908 1.000 16.87539 ? 103  ILE A CG1 1 
ATOM   442  C  CG2 . ILE A  1 72  ? 30.68974 -12.98537 -13.23424 1.000 18.93721 ? 103  ILE A CG2 1 
ATOM   443  C  CD1 . ILE A  1 72  ? 29.71279 -10.22717 -12.31656 1.000 19.78688 ? 103  ILE A CD1 1 
ATOM   444  N  N   . LEU A  1 73  ? 30.09082 -13.84102 -16.57405 1.000 17.96803 ? 104  LEU A N   1 
ATOM   445  C  CA  . LEU A  1 73  ? 30.02485 -15.24636 -16.95581 1.000 18.81468 ? 104  LEU A CA  1 
ATOM   446  C  C   . LEU A  1 73  ? 30.71933 -15.53358 -18.28444 1.000 17.96971 ? 104  LEU A C   1 
ATOM   447  O  O   . LEU A  1 73  ? 31.26353 -16.63213 -18.44732 1.000 17.50016 ? 104  LEU A O   1 
ATOM   448  C  CB  . LEU A  1 73  ? 28.56789 -15.72196 -16.98004 1.000 20.07180 ? 104  LEU A CB  1 
ATOM   449  C  CG  . LEU A  1 73  ? 28.14728 -16.12911 -15.56069 1.000 25.49924 ? 104  LEU A CG  1 
ATOM   450  C  CD1 . LEU A  1 73  ? 26.66727 -16.37281 -15.43634 1.000 26.56285 ? 104  LEU A CD1 1 
ATOM   451  C  CD2 . LEU A  1 73  ? 28.90754 -17.37891 -15.10980 1.000 25.62528 ? 104  LEU A CD2 1 
ATOM   452  N  N   . THR A  1 74  ? 30.74199 -14.57955 -19.22720 1.000 17.24648 ? 105  THR A N   1 
ATOM   453  C  CA  . THR A  1 74  ? 31.47877 -14.78385 -20.47491 1.000 18.94593 ? 105  THR A CA  1 
ATOM   454  C  C   . THR A  1 74  ? 32.94088 -14.36415 -20.41247 1.000 21.10707 ? 105  THR A C   1 
ATOM   455  O  O   . THR A  1 74  ? 33.71745 -14.77325 -21.28083 1.000 20.40252 ? 105  THR A O   1 
ATOM   456  C  CB  . THR A  1 74  ? 30.85791 -14.00715 -21.64025 1.000 18.97019 ? 105  THR A CB  1 
ATOM   457  O  OG1 . THR A  1 74  ? 30.99877 -12.58855 -21.41413 1.000 18.04651 ? 105  THR A OG1 1 
ATOM   458  C  CG2 . THR A  1 74  ? 29.38293 -14.38121 -21.84110 1.000 18.79169 ? 105  THR A CG2 1 
ATOM   459  N  N   . GLY A  1 75  ? 33.33251 -13.53375 -19.44906 1.000 17.53290 ? 106  GLY A N   1 
ATOM   460  C  CA  . GLY A  1 75  ? 34.68324 -13.00766 -19.47129 1.000 17.71616 ? 106  GLY A CA  1 
ATOM   461  C  C   . GLY A  1 75  ? 34.97063 -11.95910 -20.52930 1.000 17.70944 ? 106  GLY A C   1 
ATOM   462  O  O   . GLY A  1 75  ? 36.14322 -11.64421 -20.75816 1.000 19.04706 ? 106  GLY A O   1 
ATOM   463  N  N   . ARG A  1 76  ? 33.94613 -11.40022 -21.17648 1.000 16.86063 ? 107  ARG A N   1 
ATOM   464  C  CA  . ARG A  1 76  ? 34.10960 -10.41891 -22.24094 1.000 17.97347 ? 107  ARG A CA  1 
ATOM   465  C  C   . ARG A  1 76  ? 33.24736 -9.19597  -21.97048 1.000 17.01160 ? 107  ARG A C   1 
ATOM   466  O  O   . ARG A  1 76  ? 32.14441 -9.30660  -21.43007 1.000 17.98321 ? 107  ARG A O   1 
ATOM   467  C  CB  . ARG A  1 76  ? 33.71762 -11.00459 -23.61130 1.000 18.86228 ? 107  ARG A CB  1 
ATOM   468  C  CG  . ARG A  1 76  ? 34.52371 -12.23523 -23.99621 1.000 19.78074 ? 107  ARG A CG  1 
ATOM   469  C  CD  . ARG A  1 76  ? 34.22823 -12.66955 -25.41054 1.000 24.34397 ? 107  ARG A CD  1 
ATOM   470  N  NE  . ARG A  1 76  ? 34.87219 -11.82128 -26.39955 1.000 29.24938 ? 107  ARG A NE  1 
ATOM   471  C  CZ  . ARG A  1 76  ? 34.62327 -11.88242 -27.70138 1.000 32.31620 ? 107  ARG A CZ  1 
ATOM   472  N  NH1 . ARG A  1 76  ? 33.70794 -12.70865 -28.19379 1.000 30.96218 ? 107  ARG A NH1 1 
ATOM   473  N  NH2 . ARG A  1 76  ? 35.29861 -11.08840 -28.52677 1.000 28.52677 ? 107  ARG A NH2 1 
ATOM   474  N  N   . TYR A  1 77  ? 33.74778 -8.03051  -22.37637 1.000 16.44986 ? 108  TYR A N   1 
ATOM   475  C  CA  . TYR A  1 77  ? 32.93435 -6.82785  -22.33550 1.000 18.53512 ? 108  TYR A CA  1 
ATOM   476  C  C   . TYR A  1 77  ? 31.63365 -7.06126  -23.10199 1.000 20.39564 ? 108  TYR A C   1 
ATOM   477  O  O   . TYR A  1 77  ? 31.63991 -7.73331  -24.14154 1.000 17.19834 ? 108  TYR A O   1 
ATOM   478  C  CB  . TYR A  1 77  ? 33.68620 -5.64864  -22.94905 1.000 18.68428 ? 108  TYR A CB  1 
ATOM   479  C  CG  . TYR A  1 77  ? 34.65733 -4.97997  -22.01901 1.000 18.53799 ? 108  TYR A CG  1 
ATOM   480  C  CD1 . TYR A  1 77  ? 34.20558 -4.12068  -21.02219 1.000 18.06374 ? 108  TYR A CD1 1 
ATOM   481  C  CD2 . TYR A  1 77  ? 36.02690 -5.17465  -22.15390 1.000 17.05997 ? 108  TYR A CD2 1 
ATOM   482  C  CE1 . TYR A  1 77  ? 35.08884 -3.47978  -20.17881 1.000 18.04017 ? 108  TYR A CE1 1 
ATOM   483  C  CE2 . TYR A  1 77  ? 36.92781 -4.52798  -21.31427 1.000 18.16879 ? 108  TYR A CE2 1 
ATOM   484  C  CZ  . TYR A  1 77  ? 36.44599 -3.68484  -20.32439 1.000 18.83185 ? 108  TYR A CZ  1 
ATOM   485  O  OH  . TYR A  1 77  ? 37.32697 -3.04137  -19.47847 1.000 19.01400 ? 108  TYR A OH  1 
ATOM   486  N  N   . PRO A  1 78  ? 30.50578 -6.53105  -22.62925 1.000 18.56874 ? 109  PRO A N   1 
ATOM   487  C  CA  . PRO A  1 78  ? 29.23061 -6.80662  -23.32028 1.000 16.28498 ? 109  PRO A CA  1 
ATOM   488  C  C   . PRO A  1 78  ? 29.16545 -6.18172  -24.70118 1.000 18.70779 ? 109  PRO A C   1 
ATOM   489  O  O   . PRO A  1 78  ? 28.35440 -6.62075  -25.52919 1.000 19.53800 ? 109  PRO A O   1 
ATOM   490  C  CB  . PRO A  1 78  ? 28.17925 -6.21515  -22.37529 1.000 18.20275 ? 109  PRO A CB  1 
ATOM   491  C  CG  . PRO A  1 78  ? 28.93191 -5.10684  -21.64381 1.000 17.62995 ? 109  PRO A CG  1 
ATOM   492  C  CD  . PRO A  1 78  ? 30.33560 -5.65094  -21.45627 1.000 17.94321 ? 109  PRO A CD  1 
ATOM   493  N  N   . HIS A  1 79  ? 30.00520 -5.18245  -24.97700 1.000 16.60139 ? 110  HIS A N   1 
ATOM   494  C  CA  . HIS A  1 79  ? 30.06288 -4.57268  -26.30046 1.000 18.22737 ? 110  HIS A CA  1 
ATOM   495  C  C   . HIS A  1 79  ? 30.65691 -5.51179  -27.33553 1.000 18.76536 ? 110  HIS A C   1 
ATOM   496  O  O   . HIS A  1 79  ? 30.52476 -5.25125  -28.53690 1.000 21.35190 ? 110  HIS A O   1 
ATOM   497  C  CB  . HIS A  1 79  ? 30.89471 -3.29128  -26.24459 1.000 18.04737 ? 110  HIS A CB  1 
ATOM   498  C  CG  . HIS A  1 79  ? 30.70827 -2.51678  -24.97850 1.000 19.51180 ? 110  HIS A CG  1 
ATOM   499  N  ND1 . HIS A  1 79  ? 31.23648 -2.92821  -23.77174 1.000 21.42288 ? 110  HIS A ND1 1 
ATOM   500  C  CD2 . HIS A  1 79  ? 30.02097 -1.37994  -24.72434 1.000 18.49801 ? 110  HIS A CD2 1 
ATOM   501  C  CE1 . HIS A  1 79  ? 30.88729 -2.06697  -22.82898 1.000 19.19023 ? 110  HIS A CE1 1 
ATOM   502  N  NE2 . HIS A  1 79  ? 30.15427 -1.11718  -23.38213 1.000 18.10010 ? 110  HIS A NE2 1 
ATOM   503  N  N   . LEU A  1 80  ? 31.32125 -6.57962  -26.89613 1.000 19.95217 ? 111  LEU A N   1 
ATOM   504  C  CA  . LEU A  1 80  ? 31.89092 -7.57167  -27.79931 1.000 17.84579 ? 111  LEU A CA  1 
ATOM   505  C  C   . LEU A  1 80  ? 30.97590 -8.76477  -28.00599 1.000 21.78171 ? 111  LEU A C   1 
ATOM   506  O  O   . LEU A  1 80  ? 31.19025 -9.54566  -28.94363 1.000 21.90552 ? 111  LEU A O   1 
ATOM   507  C  CB  . LEU A  1 80  ? 33.24107 -8.06465  -27.26366 1.000 19.29589 ? 111  LEU A CB  1 
ATOM   508  C  CG  . LEU A  1 80  ? 34.48724 -7.20744  -27.53558 1.000 24.98440 ? 111  LEU A CG  1 
ATOM   509  C  CD1 . LEU A  1 80  ? 34.81678 -7.23233  -29.00841 1.000 27.86589 ? 111  LEU A CD1 1 
ATOM   510  C  CD2 . LEU A  1 80  ? 34.35048 -5.77438  -27.04566 1.000 25.46724 ? 111  LEU A CD2 1 
ATOM   511  N  N   . THR A  1 81  ? 29.97076 -8.92790  -27.15017 1.000 20.75514 ? 112  THR A N   1 
ATOM   512  C  CA  . THR A  1 81  ? 29.04342 -10.04260 -27.23254 1.000 21.80560 ? 112  THR A CA  1 
ATOM   513  C  C   . THR A  1 81  ? 27.63857 -9.60485  -27.61542 1.000 21.24338 ? 112  THR A C   1 
ATOM   514  O  O   . THR A  1 81  ? 26.75711 -10.45812 -27.74910 1.000 25.06636 ? 112  THR A O   1 
ATOM   515  C  CB  . THR A  1 81  ? 29.01611 -10.79999 -25.89650 1.000 21.17458 ? 112  THR A CB  1 
ATOM   516  O  OG1 . THR A  1 81  ? 28.62452 -9.90423  -24.83806 1.000 21.13674 ? 112  THR A OG1 1 
ATOM   517  C  CG2 . THR A  1 81  ? 30.39847 -11.36238 -25.57635 1.000 22.41754 ? 112  THR A CG2 1 
ATOM   518  N  N   . GLY A  1 82  ? 27.40884 -8.30357  -27.80680 1.000 21.08305 ? 113  GLY A N   1 
ATOM   519  C  CA  . GLY A  1 82  ? 26.10132 -7.84225  -28.22698 1.000 23.20154 ? 113  GLY A CA  1 
ATOM   520  C  C   . GLY A  1 82  ? 25.09399 -7.74158  -27.10772 1.000 20.29968 ? 113  GLY A C   1 
ATOM   521  O  O   . GLY A  1 82  ? 23.88987 -7.67884  -27.36934 1.000 19.51440 ? 113  GLY A O   1 
ATOM   522  N  N   . THR A  1 83  ? 25.55806 -7.70688  -25.85515 1.000 17.73151 ? 114  THR A N   1 
ATOM   523  C  CA  . THR A  1 83  ? 24.68340 -7.79014  -24.69678 1.000 18.08659 ? 114  THR A CA  1 
ATOM   524  C  C   . THR A  1 83  ? 24.80611 -6.55826  -23.80045 1.000 19.25742 ? 114  THR A C   1 
ATOM   525  O  O   . THR A  1 83  ? 24.65061 -6.65820  -22.58361 1.000 18.42857 ? 114  THR A O   1 
ATOM   526  C  CB  . THR A  1 83  ? 24.98723 -9.06714  -23.91481 1.000 18.71588 ? 114  THR A CB  1 
ATOM   527  O  OG1 . THR A  1 83  ? 26.37731 -9.09479  -23.56774 1.000 18.30337 ? 114  THR A OG1 1 
ATOM   528  C  CG2 . THR A  1 83  ? 24.69275 -10.30240 -24.79489 1.000 19.70145 ? 114  THR A CG2 1 
ATOM   529  N  N   . ALA A  1 84  ? 25.05778 -5.38692  -24.38857 1.000 16.81455 ? 115  ALA A N   1 
ATOM   530  C  CA  . ALA A  1 84  ? 25.25275 -4.16542  -23.60895 1.000 14.83220 ? 115  ALA A CA  1 
ATOM   531  C  C   . ALA A  1 84  ? 23.95879 -3.43472  -23.25482 1.000 17.14507 ? 115  ALA A C   1 
ATOM   532  O  O   . ALA A  1 84  ? 24.02455 -2.35766  -22.64297 1.000 18.05557 ? 115  ALA A O   1 
ATOM   533  C  CB  . ALA A  1 84  ? 26.20155 -3.21162  -24.35209 1.000 20.10893 ? 115  ALA A CB  1 
ATOM   534  N  N   . TYR A  1 85  ? 22.79279 -3.97142  -23.61089 1.000 17.59139 ? 116  TYR A N   1 
ATOM   535  C  CA  . TYR A  1 85  ? 21.51951 -3.50304  -23.07863 1.000 17.57137 ? 116  TYR A CA  1 
ATOM   536  C  C   . TYR A  1 85  ? 20.88596 -4.59960  -22.23292 1.000 15.95609 ? 116  TYR A C   1 
ATOM   537  O  O   . TYR A  1 85  ? 21.09423 -5.78855  -22.47506 1.000 17.58561 ? 116  TYR A O   1 
ATOM   538  C  CB  . TYR A  1 85  ? 20.52726 -3.10944  -24.18309 1.000 16.50789 ? 116  TYR A CB  1 
ATOM   539  C  CG  . TYR A  1 85  ? 20.85682 -1.83685  -24.93202 1.000 17.81014 ? 116  TYR A CG  1 
ATOM   540  C  CD1 . TYR A  1 85  ? 20.38862 -0.60033  -24.49349 1.000 17.19518 ? 116  TYR A CD1 1 
ATOM   541  C  CD2 . TYR A  1 85  ? 21.60727 -1.87687  -26.10321 1.000 16.71866 ? 116  TYR A CD2 1 
ATOM   542  C  CE1 . TYR A  1 85  ? 20.67250 0.57731   -25.20131 1.000 17.76197 ? 116  TYR A CE1 1 
ATOM   543  C  CE2 . TYR A  1 85  ? 21.89990 -0.71604  -26.80340 1.000 18.32705 ? 116  TYR A CE2 1 
ATOM   544  C  CZ  . TYR A  1 85  ? 21.42961 0.50515   -26.35430 1.000 16.43713 ? 116  TYR A CZ  1 
ATOM   545  O  OH  . TYR A  1 85  ? 21.70894 1.65368   -27.05426 1.000 18.38913 ? 116  TYR A OH  1 
ATOM   546  N  N   . ASN A  1 86  ? 20.07601 -4.18785  -21.26124 1.000 17.33354 ? 117  ASN A N   1 
ATOM   547  C  CA  . ASN A  1 86  ? 19.27656 -5.13848  -20.49136 1.000 17.33942 ? 117  ASN A CA  1 
ATOM   548  C  C   . ASN A  1 86  ? 18.23594 -5.82202  -21.37164 1.000 17.53756 ? 117  ASN A C   1 
ATOM   549  O  O   . ASN A  1 86  ? 17.64926 -5.19818  -22.25995 1.000 18.15998 ? 117  ASN A O   1 
ATOM   550  C  CB  . ASN A  1 86  ? 18.54240 -4.42108  -19.35345 1.000 17.54954 ? 117  ASN A CB  1 
ATOM   551  C  CG  . ASN A  1 86  ? 19.32737 -4.42049  -18.04607 1.000 18.56689 ? 117  ASN A CG  1 
ATOM   552  O  OD1 . ASN A  1 86  ? 20.44225 -4.92619  -17.97719 1.000 18.18440 ? 117  ASN A OD1 1 
ATOM   553  N  ND2 . ASN A  1 86  ? 18.72993 -3.84499  -16.99592 1.000 18.78702 ? 117  ASN A ND2 1 
ATOM   554  N  N   . LEU A  1 87  ? 17.97363 -7.09815  -21.09377 1.000 17.62210 ? 118  LEU A N   1 
ATOM   555  C  CA  . LEU A  1 87  ? 16.73208 -7.69853  -21.56468 1.000 18.43998 ? 118  LEU A CA  1 
ATOM   556  C  C   . LEU A  1 87  ? 15.55903 -7.01476  -20.87614 1.000 22.98111 ? 118  LEU A C   1 
ATOM   557  O  O   . LEU A  1 87  ? 15.63782 -6.66420  -19.69706 1.000 21.52598 ? 118  LEU A O   1 
ATOM   558  C  CB  . LEU A  1 87  ? 16.71960 -9.19225  -21.26328 1.000 17.95849 ? 118  LEU A CB  1 
ATOM   559  C  CG  . LEU A  1 87  ? 17.75236 -10.02811 -22.01650 1.000 18.29654 ? 118  LEU A CG  1 
ATOM   560  C  CD1 . LEU A  1 87  ? 17.91737 -11.39680 -21.37205 1.000 19.99689 ? 118  LEU A CD1 1 
ATOM   561  C  CD2 . LEU A  1 87  ? 17.29995 -10.16831 -23.47352 1.000 18.81596 ? 118  LEU A CD2 1 
ATOM   562  N  N   . PHE A  1 88  ? 14.47063 -6.81004  -21.61698 1.000 20.16275 ? 119  PHE A N   1 
ATOM   563  C  CA  . PHE A  1 88  ? 13.29367 -6.17915  -21.04551 1.000 20.04168 ? 119  PHE A CA  1 
ATOM   564  C  C   . PHE A  1 88  ? 12.60158 -7.15522  -20.09750 1.000 21.30702 ? 119  PHE A C   1 
ATOM   565  O  O   . PHE A  1 88  ? 12.81923 -8.36269  -20.15235 1.000 21.80028 ? 119  PHE A O   1 
ATOM   566  C  CB  . PHE A  1 88  ? 12.34123 -5.74104  -22.16116 1.000 25.01126 ? 119  PHE A CB  1 
ATOM   567  C  CG  . PHE A  1 88  ? 11.46629 -4.57576  -21.79848 1.000 22.14473 ? 119  PHE A CG  1 
ATOM   568  C  CD1 . PHE A  1 88  ? 11.98766 -3.28911  -21.75179 1.000 21.94624 ? 119  PHE A CD1 1 
ATOM   569  C  CD2 . PHE A  1 88  ? 10.11422 -4.75507  -21.53297 1.000 21.53696 ? 119  PHE A CD2 1 
ATOM   570  C  CE1 . PHE A  1 88  ? 11.18284 -2.20400  -21.43449 1.000 21.86459 ? 119  PHE A CE1 1 
ATOM   571  C  CE2 . PHE A  1 88  ? 9.30634  -3.66840  -21.21093 1.000 22.67802 ? 119  PHE A CE2 1 
ATOM   572  C  CZ  . PHE A  1 88  ? 9.84230  -2.39574  -21.15986 1.000 23.36960 ? 119  PHE A CZ  1 
ATOM   573  N  N   . HIS A  1 89  ? 11.75669 -6.63259  -19.21449 1.000 20.42933 ? 120  HIS A N   1 
ATOM   574  C  CA  . HIS A  1 89  ? 11.01898 -7.55703  -18.36464 1.000 25.39443 ? 120  HIS A CA  1 
ATOM   575  C  C   . HIS A  1 89  ? 10.14238 -8.46774  -19.22197 1.000 26.38918 ? 120  HIS A C   1 
ATOM   576  O  O   . HIS A  1 89  ? 9.64219  -8.06761  -20.27838 1.000 24.10880 ? 120  HIS A O   1 
ATOM   577  C  CB  . HIS A  1 89  ? 10.19315 -6.80837  -17.31411 1.000 31.95275 ? 120  HIS A CB  1 
ATOM   578  C  CG  . HIS A  1 89  ? 8.89194  -6.25639  -17.80629 1.000 35.14267 ? 120  HIS A CG  1 
ATOM   579  N  ND1 . HIS A  1 89  ? 7.74862  -7.02228  -17.90898 1.000 37.74419 ? 120  HIS A ND1 1 
ATOM   580  C  CD2 . HIS A  1 89  ? 8.53446  -4.99941  -18.16530 1.000 41.34044 ? 120  HIS A CD2 1 
ATOM   581  C  CE1 . HIS A  1 89  ? 6.75338  -6.26839  -18.34575 1.000 40.63289 ? 120  HIS A CE1 1 
ATOM   582  N  NE2 . HIS A  1 89  ? 7.20260  -5.03639  -18.50613 1.000 40.52767 ? 120  HIS A NE2 1 
ATOM   583  N  N   . ASN A  1 90  ? 10.01210 -9.71903  -18.78518 1.000 22.13639 ? 121  ASN A N   1 
ATOM   584  C  CA  . ASN A  1 90  ? 9.21668  -10.71973 -19.49667 1.000 25.31494 ? 121  ASN A CA  1 
ATOM   585  C  C   . ASN A  1 90  ? 9.73118  -10.95061 -20.91612 1.000 25.58111 ? 121  ASN A C   1 
ATOM   586  O  O   . ASN A  1 90  ? 8.95569  -11.17659 -21.84626 1.000 25.88633 ? 121  ASN A O   1 
ATOM   587  C  CB  . ASN A  1 90  ? 7.73590  -10.32980 -19.50511 1.000 26.01370 ? 121  ASN A CB  1 
ATOM   588  C  CG  . ASN A  1 90  ? 7.11058  -10.41893 -18.12135 1.000 29.32335 ? 121  ASN A CG  1 
ATOM   589  O  OD1 . ASN A  1 90  ? 7.35815  -9.57435  -17.25791 1.000 30.20785 ? 121  ASN A OD1 1 
ATOM   590  N  ND2 . ASN A  1 90  ? 6.30528  -11.45066 -17.90034 1.000 34.62408 ? 121  ASN A ND2 1 
ATOM   591  N  N   . SER A  1 91  ? 11.05175 -10.91921 -21.08445 1.000 21.63308 ? 122  SER A N   1 
ATOM   592  C  CA  . SER A  1 91  ? 11.62491 -11.09918 -22.41011 1.000 20.51334 ? 122  SER A CA  1 
ATOM   593  C  C   . SER A  1 91  ? 11.33574 -12.50781 -22.92697 1.000 23.71041 ? 122  SER A C   1 
ATOM   594  O  O   . SER A  1 91  ? 11.03257 -13.42947 -22.16617 1.000 24.47225 ? 122  SER A O   1 
ATOM   595  C  CB  . SER A  1 91  ? 13.13370 -10.83854 -22.39467 1.000 21.36530 ? 122  SER A CB  1 
ATOM   596  O  OG  . SER A  1 91  ? 13.80362 -11.76845 -21.55834 1.000 22.74045 ? 122  SER A OG  1 
ATOM   597  N  N   . SER A  1 92  ? 11.45368 -12.66628 -24.24252 1.000 21.87917 ? 123  SER A N   1 
ATOM   598  C  CA  . SER A  1 92  ? 10.90923 -13.84696 -24.90604 1.000 23.81561 ? 123  SER A CA  1 
ATOM   599  C  C   . SER A  1 92  ? 11.50532 -15.14316 -24.36953 1.000 24.15886 ? 123  SER A C   1 
ATOM   600  O  O   . SER A  1 92  ? 12.72274 -15.27842 -24.19691 1.000 26.53111 ? 123  SER A O   1 
ATOM   601  C  CB  . SER A  1 92  ? 11.14033 -13.77512 -26.41330 1.000 27.86844 ? 123  SER A CB  1 
ATOM   602  O  OG  . SER A  1 92  ? 10.73680 -15.00779 -27.00582 1.000 31.18774 ? 123  SER A OG  1 
ATOM   603  N  N   . GLU A  1 93  ? 10.62958 -16.11442 -24.13663 1.000 26.11100 ? 124  GLU A N   1 
ATOM   604  C  CA  . GLU A  1 93  ? 11.02882 -17.42488 -23.65973 1.000 26.50187 ? 124  GLU A CA  1 
ATOM   605  C  C   . GLU A  1 93  ? 11.11294 -18.44748 -24.78715 1.000 26.78509 ? 124  GLU A C   1 
ATOM   606  O  O   . GLU A  1 93  ? 11.28524 -19.64024 -24.52111 1.000 27.84653 ? 124  GLU A O   1 
ATOM   607  C  CB  . GLU A  1 93  ? 10.06736 -17.87367 -22.55742 1.000 28.81972 ? 124  GLU A CB  1 
ATOM   608  C  CG  . GLU A  1 93  ? 10.16653 -16.95324 -21.33919 1.000 29.77334 ? 124  GLU A CG  1 
ATOM   609  C  CD  . GLU A  1 93  ? 9.07500  -17.15085 -20.31711 1.000 38.75235 ? 124  GLU A CD  1 
ATOM   610  O  OE1 . GLU A  1 93  ? 8.33114  -18.14784 -20.41753 1.000 39.92117 ? 124  GLU A OE1 1 
ATOM   611  O  OE2 . GLU A  1 93  ? 8.96934  -16.29804 -19.40236 1.000 36.45383 ? 124  GLU A OE2 1 
ATOM   612  N  N   . ASP A  1 94  ? 11.03528 -17.99541 -26.03628 1.000 30.20217 ? 125  ASP A N   1 
ATOM   613  C  CA  . ASP A  1 94  ? 11.16040 -18.84718 -27.21427 1.000 28.40439 ? 125  ASP A CA  1 
ATOM   614  C  C   . ASP A  1 94  ? 12.59227 -18.78117 -27.73012 1.000 29.71313 ? 125  ASP A C   1 
ATOM   615  O  O   . ASP A  1 94  ? 13.11481 -17.68807 -27.98048 1.000 30.66228 ? 125  ASP A O   1 
ATOM   616  C  CB  . ASP A  1 94  ? 10.17394 -18.39035 -28.29510 1.000 30.53196 ? 125  ASP A CB  1 
ATOM   617  C  CG  . ASP A  1 94  ? 10.13213 -19.31848 -29.51238 1.000 40.21654 ? 125  ASP A CG  1 
ATOM   618  O  OD1 . ASP A  1 94  ? 11.03457 -20.16628 -29.69428 1.000 41.16768 ? 125  ASP A OD1 1 
ATOM   619  O  OD2 . ASP A  1 94  ? 9.16751  -19.19099 -30.29765 1.000 46.65149 ? 125  ASP A OD2 1 
ATOM   620  N  N   . ASP A  1 95  ? 13.21847 -19.95364 -27.89318 1.000 29.41173 ? 126  ASP A N   1 
ATOM   621  C  CA  . ASP A  1 95  ? 14.57411 -20.02288 -28.43685 1.000 28.33089 ? 126  ASP A CA  1 
ATOM   622  C  C   . ASP A  1 95  ? 14.70225 -19.24872 -29.74121 1.000 28.93598 ? 126  ASP A C   1 
ATOM   623  O  O   . ASP A  1 95  ? 15.74530 -18.64314 -30.01066 1.000 29.48713 ? 126  ASP A O   1 
ATOM   624  C  CB  . ASP A  1 95  ? 14.98129 -21.47994 -28.67516 1.000 29.81575 ? 126  ASP A CB  1 
ATOM   625  C  CG  . ASP A  1 95  ? 15.45594 -22.17430 -27.42301 1.000 32.15012 ? 126  ASP A CG  1 
ATOM   626  O  OD1 . ASP A  1 95  ? 15.55211 -21.52020 -26.36381 1.000 29.33471 ? 126  ASP A OD1 1 
ATOM   627  O  OD2 . ASP A  1 95  ? 15.73201 -23.38805 -27.49862 1.000 31.43965 ? 126  ASP A OD2 1 
ATOM   628  N  N   . LYS A  1 96  ? 13.65366 -19.27006 -30.57133 1.000 30.66922 ? 127  LYS A N   1 
ATOM   629  C  CA  . LYS A  1 96  ? 13.71597 -18.64616 -31.88985 1.000 32.71366 ? 127  LYS A CA  1 
ATOM   630  C  C   . LYS A  1 96  ? 14.00982 -17.15374 -31.82384 1.000 34.30149 ? 127  LYS A C   1 
ATOM   631  O  O   . LYS A  1 96  ? 14.54626 -16.59824 -32.78819 1.000 32.57102 ? 127  LYS A O   1 
ATOM   632  C  CB  . LYS A  1 96  ? 12.40032 -18.87421 -32.64311 1.000 33.85446 ? 127  LYS A CB  1 
ATOM   633  N  N   . ASP A  1 97  ? 13.68241 -16.49499 -30.71239 1.000 30.70736 ? 128  ASP A N   1 
ATOM   634  C  CA  . ASP A  1 97  ? 13.84260 -15.05073 -30.60405 1.000 26.97318 ? 128  ASP A CA  1 
ATOM   635  C  C   . ASP A  1 97  ? 15.23099 -14.62096 -30.14156 1.000 30.03859 ? 128  ASP A C   1 
ATOM   636  O  O   . ASP A  1 97  ? 15.55309 -13.43218 -30.24670 1.000 28.20298 ? 128  ASP A O   1 
ATOM   637  C  CB  . ASP A  1 97  ? 12.77244 -14.48995 -29.66581 1.000 28.18729 ? 128  ASP A CB  1 
ATOM   638  C  CG  . ASP A  1 97  ? 11.36335 -14.63410 -30.23731 1.000 30.94482 ? 128  ASP A CG  1 
ATOM   639  O  OD1 . ASP A  1 97  ? 11.20441 -14.47845 -31.46356 1.000 35.67863 ? 128  ASP A OD1 1 
ATOM   640  O  OD2 . ASP A  1 97  ? 10.41831 -14.90237 -29.46793 1.000 30.03575 ? 128  ASP A OD2 1 
ATOM   641  N  N   . ASN A  1 98  ? 16.05580 -15.54571 -29.63775 1.000 26.69588 ? 129  ASN A N   1 
ATOM   642  C  CA  . ASN A  1 98  ? 17.46361 -15.27583 -29.32167 1.000 26.86016 ? 129  ASN A CA  1 
ATOM   643  C  C   . ASN A  1 98  ? 17.62940 -14.14005 -28.31064 1.000 25.36225 ? 129  ASN A C   1 
ATOM   644  O  O   . ASN A  1 98  ? 18.59353 -13.37511 -28.38110 1.000 25.90242 ? 129  ASN A O   1 
ATOM   645  C  CB  . ASN A  1 98  ? 18.27526 -14.96181 -30.58375 1.000 29.69405 ? 129  ASN A CB  1 
ATOM   646  C  CG  . ASN A  1 98  ? 18.78112 -16.20960 -31.28692 1.000 36.85787 ? 129  ASN A CG  1 
ATOM   647  O  OD1 . ASN A  1 98  ? 18.92002 -17.26849 -30.68039 1.000 37.31941 ? 129  ASN A OD1 1 
ATOM   648  N  ND2 . ASN A  1 98  ? 19.06666 -16.08358 -32.57793 1.000 47.59873 ? 129  ASN A ND2 1 
ATOM   649  N  N   . MET A  1 99  ? 16.69581 -14.00884 -27.36707 1.000 25.91216 ? 130  MET A N   1 
ATOM   650  C  CA  . MET A  1 99  ? 16.77612 -12.95795 -26.34590 1.000 23.58299 ? 130  MET A CA  1 
ATOM   651  C  C   . MET A  1 99  ? 17.56419 -13.50617 -25.16115 1.000 20.86307 ? 130  MET A C   1 
ATOM   652  O  O   . MET A  1 99  ? 17.01779 -13.88331 -24.12184 1.000 22.62496 ? 130  MET A O   1 
ATOM   653  C  CB  . MET A  1 99  ? 15.38674 -12.48990 -25.93865 1.000 20.78966 ? 130  MET A CB  1 
ATOM   654  C  CG  . MET A  1 99  ? 14.69663 -11.64757 -26.98856 1.000 24.63020 ? 130  MET A CG  1 
ATOM   655  S  SD  . MET A  1 99  ? 15.48698 -10.02431 -27.07344 1.000 26.62963 ? 130  MET A SD  1 
ATOM   656  C  CE  . MET A  1 99  ? 14.51682 -9.21255  -28.34294 1.000 27.02776 ? 130  MET A CE  1 
ATOM   657  N  N   . GLY A  1 100 ? 18.87561 -13.57467 -25.34850 1.000 22.60694 ? 131  GLY A N   1 
ATOM   658  C  CA  . GLY A  1 100 ? 19.76879 -14.10010 -24.32837 1.000 20.89163 ? 131  GLY A CA  1 
ATOM   659  C  C   . GLY A  1 100 ? 21.20035 -14.02607 -24.81441 1.000 19.55991 ? 131  GLY A C   1 
ATOM   660  O  O   . GLY A  1 100 ? 21.47058 -13.79369 -25.99691 1.000 20.12817 ? 131  GLY A O   1 
ATOM   661  N  N   . VAL A  1 101 ? 22.12188 -14.20846 -23.87195 1.000 20.23199 ? 132  VAL A N   1 
ATOM   662  C  CA  . VAL A  1 101 ? 23.55194 -14.13540 -24.20496 1.000 20.28495 ? 132  VAL A CA  1 
ATOM   663  C  C   . VAL A  1 101 ? 23.89444 -15.23832 -25.20380 1.000 20.65339 ? 132  VAL A C   1 
ATOM   664  O  O   . VAL A  1 101 ? 23.50605 -16.39781 -24.98924 1.000 21.97870 ? 132  VAL A O   1 
ATOM   665  C  CB  . VAL A  1 101 ? 24.40238 -14.26546 -22.93253 1.000 20.48136 ? 132  VAL A CB  1 
ATOM   666  C  CG1 . VAL A  1 101 ? 25.90185 -14.23245 -23.25370 1.000 21.11295 ? 132  VAL A CG1 1 
ATOM   667  C  CG2 . VAL A  1 101 ? 24.04033 -13.16152 -21.95337 1.000 20.49584 ? 132  VAL A CG2 1 
ATOM   668  N  N   . PRO A  1 102 ? 24.61573 -14.94026 -26.28252 1.000 20.67115 ? 133  PRO A N   1 
ATOM   669  C  CA  . PRO A  1 102 ? 24.91475 -15.95937 -27.30142 1.000 20.65520 ? 133  PRO A CA  1 
ATOM   670  C  C   . PRO A  1 102 ? 25.40987 -17.27439 -26.71143 1.000 23.78278 ? 133  PRO A C   1 
ATOM   671  O  O   . PRO A  1 102 ? 26.32602 -17.30721 -25.88544 1.000 20.80963 ? 133  PRO A O   1 
ATOM   672  C  CB  . PRO A  1 102 ? 25.99786 -15.29041 -28.15063 1.000 25.60109 ? 133  PRO A CB  1 
ATOM   673  C  CG  . PRO A  1 102 ? 25.67858 -13.83585 -28.06284 1.000 25.52441 ? 133  PRO A CG  1 
ATOM   674  C  CD  . PRO A  1 102 ? 25.06315 -13.59769 -26.69463 1.000 21.41706 ? 133  PRO A CD  1 
ATOM   675  N  N   . VAL A  1 103 ? 24.80048 -18.37490 -27.16427 1.000 23.37140 ? 134  VAL A N   1 
ATOM   676  C  CA  . VAL A  1 103 ? 25.14058 -19.69187 -26.63585 1.000 21.96831 ? 134  VAL A CA  1 
ATOM   677  C  C   . VAL A  1 103 ? 26.55320 -20.11371 -27.02012 1.000 22.58733 ? 134  VAL A C   1 
ATOM   678  O  O   . VAL A  1 103 ? 27.13617 -20.96904 -26.34886 1.000 24.11716 ? 134  VAL A O   1 
ATOM   679  C  CB  . VAL A  1 103 ? 24.12113 -20.75101 -27.10266 1.000 25.80531 ? 134  VAL A CB  1 
ATOM   680  C  CG1 . VAL A  1 103 ? 22.71966 -20.41726 -26.58371 1.000 24.96521 ? 134  VAL A CG1 1 
ATOM   681  C  CG2 . VAL A  1 103 ? 24.12499 -20.85596 -28.61629 1.000 29.11858 ? 134  VAL A CG2 1 
ATOM   682  N  N   . GLU A  1 104 ? 27.12285 -19.52096 -28.07348 1.000 25.77909 ? 135  GLU A N   1 
ATOM   683  C  CA  . GLU A  1 104 ? 28.48207 -19.84203 -28.49062 1.000 27.88548 ? 135  GLU A CA  1 
ATOM   684  C  C   . GLU A  1 104 ? 29.53339 -19.25646 -27.55643 1.000 27.69221 ? 135  GLU A C   1 
ATOM   685  O  O   . GLU A  1 104 ? 30.69788 -19.67452 -27.60631 1.000 26.29863 ? 135  GLU A O   1 
ATOM   686  C  CB  . GLU A  1 104 ? 28.72599 -19.32770 -29.91075 1.000 28.68354 ? 135  GLU A CB  1 
ATOM   687  C  CG  . GLU A  1 104 ? 27.78273 -19.90214 -30.95942 1.000 39.09365 ? 135  GLU A CG  1 
ATOM   688  C  CD  . GLU A  1 104 ? 26.50776 -19.08415 -31.14466 1.000 43.73278 ? 135  GLU A CD  1 
ATOM   689  O  OE1 . GLU A  1 104 ? 26.29112 -18.10376 -30.39455 1.000 33.79760 ? 135  GLU A OE1 1 
ATOM   690  O  OE2 . GLU A  1 104 ? 25.71844 -19.42620 -32.05537 1.000 47.54414 ? 135  GLU A OE2 1 
ATOM   691  N  N   . GLU A  1 105 ? 29.15152 -18.29824 -26.71385 1.000 23.76445 ? 136  GLU A N   1 
ATOM   692  C  CA  . GLU A  1 105 ? 30.08861 -17.61566 -25.82712 1.000 22.65310 ? 136  GLU A CA  1 
ATOM   693  C  C   . GLU A  1 105 ? 30.13738 -18.39556 -24.51862 1.000 24.68035 ? 136  GLU A C   1 
ATOM   694  O  O   . GLU A  1 105 ? 29.35401 -18.15147 -23.60108 1.000 26.57344 ? 136  GLU A O   1 
ATOM   695  C  CB  . GLU A  1 105 ? 29.64648 -16.17041 -25.61864 1.000 24.21136 ? 136  GLU A CB  1 
ATOM   696  C  CG  . GLU A  1 105 ? 30.72352 -15.27712 -25.06286 1.000 24.85290 ? 136  GLU A CG  1 
ATOM   697  C  CD  . GLU A  1 105 ? 31.91624 -15.14451 -25.98709 1.000 23.41010 ? 136  GLU A CD  1 
ATOM   698  O  OE1 . GLU A  1 105 ? 31.78641 -14.53849 -27.07137 1.000 25.52473 ? 136  GLU A OE1 1 
ATOM   699  O  OE2 . GLU A  1 105 ? 32.99170 -15.64232 -25.61623 1.000 28.12724 ? 136  GLU A OE2 1 
ATOM   700  N  N   . THR A  1 106 ? 31.08070 -19.33578 -24.42883 1.000 21.88487 ? 137  THR A N   1 
ATOM   701  C  CA  . THR A  1 106 ? 31.07968 -20.33054 -23.35752 1.000 21.12605 ? 137  THR A CA  1 
ATOM   702  C  C   . THR A  1 106 ? 31.28415 -19.69141 -21.98401 1.000 20.74820 ? 137  THR A C   1 
ATOM   703  O  O   . THR A  1 106 ? 32.25935 -18.96848 -21.76414 1.000 20.26504 ? 137  THR A O   1 
ATOM   704  C  CB  . THR A  1 106 ? 32.17970 -21.35904 -23.61389 1.000 26.43138 ? 137  THR A CB  1 
ATOM   705  O  OG1 . THR A  1 106 ? 32.04484 -21.88115 -24.94503 1.000 25.14711 ? 137  THR A OG1 1 
ATOM   706  C  CG2 . THR A  1 106 ? 32.09618 -22.49628 -22.60336 1.000 23.78166 ? 137  THR A CG2 1 
ATOM   707  N  N   . TYR A  1 107 ? 30.38215 -19.99820 -21.05232 1.000 21.01538 ? 138  TYR A N   1 
ATOM   708  C  CA  . TYR A  1 107 ? 30.46042 -19.46520 -19.69680 1.000 20.37412 ? 138  TYR A CA  1 
ATOM   709  C  C   . TYR A  1 107 ? 31.55489 -20.16324 -18.89914 1.000 21.64721 ? 138  TYR A C   1 
ATOM   710  O  O   . TYR A  1 107 ? 31.87716 -21.33215 -19.13459 1.000 20.93741 ? 138  TYR A O   1 
ATOM   711  C  CB  . TYR A  1 107 ? 29.13564 -19.64527 -18.95955 1.000 18.64166 ? 138  TYR A CB  1 
ATOM   712  C  CG  . TYR A  1 107 ? 27.99970 -18.74163 -19.39360 1.000 17.93051 ? 138  TYR A CG  1 
ATOM   713  C  CD1 . TYR A  1 107 ? 28.14898 -17.82175 -20.42771 1.000 18.73337 ? 138  TYR A CD1 1 
ATOM   714  C  CD2 . TYR A  1 107 ? 26.77572 -18.79800 -18.73399 1.000 18.65865 ? 138  TYR A CD2 1 
ATOM   715  C  CE1 . TYR A  1 107 ? 27.09225 -16.99975 -20.80547 1.000 18.66140 ? 138  TYR A CE1 1 
ATOM   716  C  CE2 . TYR A  1 107 ? 25.71727 -17.98867 -19.09942 1.000 19.80850 ? 138  TYR A CE2 1 
ATOM   717  C  CZ  . TYR A  1 107 ? 25.87711 -17.09684 -20.13633 1.000 17.08080 ? 138  TYR A CZ  1 
ATOM   718  O  OH  . TYR A  1 107 ? 24.81172 -16.30609 -20.48781 1.000 17.23671 ? 138  TYR A OH  1 
ATOM   719  N  N   . MET A  1 108 ? 32.11302 -19.44483 -17.91774 1.000 18.28450 ? 139  MET A N   1 
ATOM   720  C  CA  . MET A  1 108 ? 33.11842 -20.07935 -17.07127 1.000 17.04518 ? 139  MET A CA  1 
ATOM   721  C  C   . MET A  1 108 ? 32.53337 -21.23416 -16.27701 1.000 20.60304 ? 139  MET A C   1 
ATOM   722  O  O   . MET A  1 108 ? 33.25741 -22.16970 -15.92569 1.000 22.19239 ? 139  MET A O   1 
ATOM   723  C  CB  . MET A  1 108 ? 33.76508 -19.06628 -16.13161 1.000 19.16323 ? 139  MET A CB  1 
ATOM   724  C  CG  . MET A  1 108 ? 32.80774 -18.26527 -15.26848 1.000 19.11080 ? 139  MET A CG  1 
ATOM   725  S  SD  . MET A  1 108 ? 33.81974 -17.42861 -14.02122 1.000 22.34964 ? 139  MET A SD  1 
ATOM   726  C  CE  . MET A  1 108 ? 32.62686 -16.27749 -13.34459 1.000 21.25296 ? 139  MET A CE  1 
ATOM   727  N  N   . SER A  1 109 ? 31.22968 -21.19358 -15.99094 1.000 20.56802 ? 140  SER A N   1 
ATOM   728  C  CA  . SER A  1 109 ? 30.59039 -22.32028 -15.32030 1.000 17.68379 ? 140  SER A CA  1 
ATOM   729  C  C   . SER A  1 109 ? 30.73641 -23.60468 -16.13260 1.000 19.61924 ? 140  SER A C   1 
ATOM   730  O  O   . SER A  1 109 ? 31.04503 -24.66688 -15.58061 1.000 21.36052 ? 140  SER A O   1 
ATOM   731  C  CB  . SER A  1 109 ? 29.11978 -21.99856 -15.08088 1.000 19.48237 ? 140  SER A CB  1 
ATOM   732  O  OG  . SER A  1 109 ? 28.56244 -21.36866 -16.23313 1.000 19.03405 ? 140  SER A OG  1 
ATOM   733  N  N   . LYS A  1 110 ? 30.52251 -23.52226 -17.44798 1.000 20.39471 ? 141  LYS A N   1 
ATOM   734  C  CA  . LYS A  1 110 ? 30.66982 -24.70231 -18.29500 1.000 21.09285 ? 141  LYS A CA  1 
ATOM   735  C  C   . LYS A  1 110 ? 32.11632 -25.18338 -18.32777 1.000 22.89533 ? 141  LYS A C   1 
ATOM   736  O  O   . LYS A  1 110 ? 32.37533 -26.39301 -18.33024 1.000 23.11423 ? 141  LYS A O   1 
ATOM   737  C  CB  . LYS A  1 110 ? 30.16722 -24.38480 -19.70440 1.000 21.15357 ? 141  LYS A CB  1 
ATOM   738  C  CG  . LYS A  1 110 ? 30.27960 -25.53631 -20.70738 1.000 28.27115 ? 141  LYS A CG  1 
ATOM   739  C  CD  . LYS A  1 110 ? 29.07410 -26.45422 -20.63370 1.000 35.59453 ? 141  LYS A CD  1 
ATOM   740  C  CE  . LYS A  1 110 ? 27.76337 -25.68200 -20.82686 1.000 37.77031 ? 141  LYS A CE  1 
ATOM   741  N  NZ  . LYS A  1 110 ? 27.35674 -25.44356 -22.25285 1.000 36.16122 ? 141  LYS A NZ  1 
ATOM   742  N  N   . VAL A  1 111 ? 33.07495 -24.25221 -18.34821 1.000 21.32639 ? 142  VAL A N   1 
ATOM   743  C  CA  . VAL A  1 111 ? 34.48727 -24.63038 -18.32811 1.000 21.47317 ? 142  VAL A CA  1 
ATOM   744  C  C   . VAL A  1 111 ? 34.83278 -25.35360 -17.03244 1.000 22.23741 ? 142  VAL A C   1 
ATOM   745  O  O   . VAL A  1 111 ? 35.52007 -26.38313 -17.03677 1.000 23.45053 ? 142  VAL A O   1 
ATOM   746  C  CB  . VAL A  1 111 ? 35.37216 -23.38892 -18.52681 1.000 21.52068 ? 142  VAL A CB  1 
ATOM   747  C  CG1 . VAL A  1 111 ? 36.83298 -23.75884 -18.34423 1.000 23.26226 ? 142  VAL A CG1 1 
ATOM   748  C  CG2 . VAL A  1 111 ? 35.11201 -22.75893 -19.89552 1.000 23.22827 ? 142  VAL A CG2 1 
ATOM   749  N  N   . LEU A  1 112 ? 34.37281 -24.81742 -15.89856 1.000 20.09694 ? 143  LEU A N   1 
ATOM   750  C  CA  . LEU A  1 112 ? 34.64052 -25.46417 -14.61979 1.000 19.85403 ? 143  LEU A CA  1 
ATOM   751  C  C   . LEU A  1 112 ? 33.92485 -26.80558 -14.51355 1.000 20.74208 ? 143  LEU A C   1 
ATOM   752  O  O   . LEU A  1 112 ? 34.48957 -27.77102 -13.98992 1.000 23.49230 ? 143  LEU A O   1 
ATOM   753  C  CB  . LEU A  1 112 ? 34.22367 -24.54449 -13.46709 1.000 21.36796 ? 143  LEU A CB  1 
ATOM   754  C  CG  . LEU A  1 112 ? 34.96306 -23.19882 -13.43330 1.000 24.12336 ? 143  LEU A CG  1 
ATOM   755  C  CD1 . LEU A  1 112 ? 34.34363 -22.21550 -12.44022 1.000 24.59880 ? 143  LEU A CD1 1 
ATOM   756  C  CD2 . LEU A  1 112 ? 36.39478 -23.42278 -13.08839 1.000 25.95616 ? 143  LEU A CD2 1 
ATOM   757  N  N   . GLN A  1 113 ? 32.67916 -26.87679 -14.99008 1.000 20.76183 ? 144  GLN A N   1 
ATOM   758  C  CA  . GLN A  1 113 ? 31.94119 -28.13695 -14.98078 1.000 22.50847 ? 144  GLN A CA  1 
ATOM   759  C  C   . GLN A  1 113 ? 32.68975 -29.20299 -15.77020 1.000 23.93262 ? 144  GLN A C   1 
ATOM   760  O  O   . GLN A  1 113 ? 32.85526 -30.33884 -15.30263 1.000 23.84728 ? 144  GLN A O   1 
ATOM   761  C  CB  . GLN A  1 113 ? 30.53923 -27.90677 -15.54998 1.000 22.43856 ? 144  GLN A CB  1 
ATOM   762  C  CG  . GLN A  1 113 ? 29.57999 -29.08652 -15.45275 1.000 24.40991 ? 144  GLN A CG  1 
ATOM   763  C  CD  . GLN A  1 113 ? 28.29821 -28.81725 -16.20605 1.000 26.28815 ? 144  GLN A CD  1 
ATOM   764  O  OE1 . GLN A  1 113 ? 28.32954 -28.42381 -17.37161 1.000 28.45210 ? 144  GLN A OE1 1 
ATOM   765  N  NE2 . GLN A  1 113 ? 27.16536 -29.00710 -15.54481 1.000 25.33233 ? 144  GLN A NE2 1 
ATOM   766  N  N   . ASN A  1 114 ? 33.20005 -28.83257 -16.94552 1.000 23.81238 ? 145  ASN A N   1 
ATOM   767  C  CA  . ASN A  1 114 ? 33.97388 -29.76133 -17.76091 1.000 26.35950 ? 145  ASN A CA  1 
ATOM   768  C  C   . ASN A  1 114 ? 35.29802 -30.13731 -17.11463 1.000 26.94529 ? 145  ASN A C   1 
ATOM   769  O  O   . ASN A  1 114 ? 35.87732 -31.16952 -17.47318 1.000 30.15200 ? 145  ASN A O   1 
ATOM   770  C  CB  . ASN A  1 114 ? 34.22115 -29.16562 -19.14706 1.000 26.06944 ? 145  ASN A CB  1 
ATOM   771  C  CG  . ASN A  1 114 ? 32.96207 -29.12696 -19.99941 1.000 32.28054 ? 145  ASN A CG  1 
ATOM   772  O  OD1 . ASN A  1 114 ? 31.99421 -29.84698 -19.73428 1.000 40.46712 ? 145  ASN A OD1 1 
ATOM   773  N  ND2 . ASN A  1 114 ? 32.96817 -28.28560 -21.02719 1.000 36.91780 ? 145  ASN A ND2 1 
ATOM   774  N  N   . ALA A  1 115 ? 35.79505 -29.33364 -16.17899 1.000 24.09703 ? 146  ALA A N   1 
ATOM   775  C  CA  . ALA A  1 115 ? 37.00587 -29.65841 -15.44766 1.000 24.01914 ? 146  ALA A CA  1 
ATOM   776  C  C   . ALA A  1 115 ? 36.71856 -30.39763 -14.15053 1.000 23.35042 ? 146  ALA A C   1 
ATOM   777  O  O   . ALA A  1 115 ? 37.61919 -30.53972 -13.32364 1.000 25.08960 ? 146  ALA A O   1 
ATOM   778  C  CB  . ALA A  1 115 ? 37.80850 -28.39031 -15.15878 1.000 23.41634 ? 146  ALA A CB  1 
ATOM   779  N  N   . GLY A  1 116 ? 35.48651 -30.84768 -13.94701 1.000 22.84961 ? 147  GLY A N   1 
ATOM   780  C  CA  . GLY A  1 116 ? 35.15176 -31.68828 -12.81821 1.000 24.85225 ? 147  GLY A CA  1 
ATOM   781  C  C   . GLY A  1 116 ? 34.61611 -30.97593 -11.59776 1.000 22.96764 ? 147  GLY A C   1 
ATOM   782  O  O   . GLY A  1 116 ? 34.52208 -31.60092 -10.53462 1.000 25.19545 ? 147  GLY A O   1 
ATOM   783  N  N   . TYR A  1 117 ? 34.26832 -29.69311 -11.70931 1.000 21.96393 ? 148  TYR A N   1 
ATOM   784  C  CA  . TYR A  1 117 ? 33.65283 -28.98476 -10.59732 1.000 21.59227 ? 148  TYR A CA  1 
ATOM   785  C  C   . TYR A  1 117 ? 32.15742 -29.27064 -10.53426 1.000 20.43146 ? 148  TYR A C   1 
ATOM   786  O  O   . TYR A  1 117 ? 31.48892 -29.40718 -11.56371 1.000 21.71971 ? 148  TYR A O   1 
ATOM   787  C  CB  . TYR A  1 117 ? 33.87844 -27.47033 -10.73198 1.000 17.18779 ? 148  TYR A CB  1 
ATOM   788  C  CG  . TYR A  1 117 ? 35.16998 -26.97326 -10.14296 1.000 21.31036 ? 148  TYR A CG  1 
ATOM   789  C  CD1 . TYR A  1 117 ? 36.39514 -27.44829 -10.59928 1.000 24.56012 ? 148  TYR A CD1 1 
ATOM   790  C  CD2 . TYR A  1 117 ? 35.16977 -26.01654 -9.13779  1.000 19.83967 ? 148  TYR A CD2 1 
ATOM   791  C  CE1 . TYR A  1 117 ? 37.58465 -26.99751 -10.05812 1.000 24.13983 ? 148  TYR A CE1 1 
ATOM   792  C  CE2 . TYR A  1 117 ? 36.35016 -25.56064 -8.59051  1.000 20.09205 ? 148  TYR A CE2 1 
ATOM   793  C  CZ  . TYR A  1 117 ? 37.55662 -26.05291 -9.05278  1.000 19.91370 ? 148  TYR A CZ  1 
ATOM   794  O  OH  . TYR A  1 117 ? 38.73993 -25.60050 -8.50499  1.000 22.78943 ? 148  TYR A OH  1 
ATOM   795  N  N   . TYR A  1 118 ? 31.63558 -29.34937 -9.31014  1.000 19.25426 ? 149  TYR A N   1 
ATOM   796  C  CA  . TYR A  1 118 ? 30.19585 -29.33391 -9.07594  1.000 20.07139 ? 149  TYR A CA  1 
ATOM   797  C  C   . TYR A  1 118 ? 29.72612 -27.88822 -9.11965  1.000 20.12443 ? 149  TYR A C   1 
ATOM   798  O  O   . TYR A  1 118 ? 30.18069 -27.06757 -8.31749  1.000 20.59628 ? 149  TYR A O   1 
ATOM   799  C  CB  . TYR A  1 118 ? 29.86848 -29.95722 -7.72439  1.000 20.14875 ? 149  TYR A CB  1 
ATOM   800  C  CG  . TYR A  1 118 ? 28.43239 -29.75205 -7.30572  1.000 22.10665 ? 149  TYR A CG  1 
ATOM   801  C  CD1 . TYR A  1 118 ? 27.40267 -30.41714 -7.95197  1.000 29.70108 ? 149  TYR A CD1 1 
ATOM   802  C  CD2 . TYR A  1 118 ? 28.10812 -28.89055 -6.26644  1.000 27.02425 ? 149  TYR A CD2 1 
ATOM   803  C  CE1 . TYR A  1 118 ? 26.08753 -30.22256 -7.58186  1.000 30.45958 ? 149  TYR A CE1 1 
ATOM   804  C  CE2 . TYR A  1 118 ? 26.79028 -28.69066 -5.88832  1.000 26.81931 ? 149  TYR A CE2 1 
ATOM   805  C  CZ  . TYR A  1 118 ? 25.79138 -29.35613 -6.55284  1.000 26.39363 ? 149  TYR A CZ  1 
ATOM   806  O  OH  . TYR A  1 118 ? 24.48281 -29.17021 -6.17885  1.000 28.41814 ? 149  TYR A OH  1 
ATOM   807  N  N   . THR A  1 119 ? 28.83367 -27.56636 -10.04637 1.000 18.91928 ? 150  THR A N   1 
ATOM   808  C  CA  . THR A  1 119 ? 28.50383 -26.17452 -10.32547 1.000 21.79991 ? 150  THR A CA  1 
ATOM   809  C  C   . THR A  1 119 ? 27.06237 -25.86103 -9.93908  1.000 20.16995 ? 150  THR A C   1 
ATOM   810  O  O   . THR A  1 119 ? 26.14576 -26.63971 -10.20915 1.000 20.98775 ? 150  THR A O   1 
ATOM   811  C  CB  . THR A  1 119 ? 28.73256 -25.85185 -11.80020 1.000 20.64684 ? 150  THR A CB  1 
ATOM   812  O  OG1 . THR A  1 119 ? 27.96145 -26.74775 -12.61179 1.000 21.90392 ? 150  THR A OG1 1 
ATOM   813  C  CG2 . THR A  1 119 ? 30.22658 -25.95831 -12.16448 1.000 19.58541 ? 150  THR A CG2 1 
ATOM   814  N  N   . SER A  1 120 ? 26.86356 -24.70294 -9.31275  1.000 18.66722 ? 151  SER A N   1 
ATOM   815  C  CA  . SER A  1 120 ? 25.56176 -24.32102 -8.77522  1.000 20.55119 ? 151  SER A CA  1 
ATOM   816  C  C   . SER A  1 120 ? 25.36212 -22.83393 -9.00697  1.000 18.70268 ? 151  SER A C   1 
ATOM   817  O  O   . SER A  1 120 ? 26.27516 -22.04851 -8.74294  1.000 20.03084 ? 151  SER A O   1 
ATOM   818  C  CB  . SER A  1 120 ? 25.48459 -24.63249 -7.27068  1.000 19.22754 ? 151  SER A CB  1 
ATOM   819  O  OG  . SER A  1 120 ? 24.47830 -23.86750 -6.61996  1.000 27.78162 ? 151  SER A OG  1 
ATOM   820  N  N   . ALA A  1 121 ? 24.18548 -22.45763 -9.51395  1.000 17.81975 ? 152  ALA A N   1 
ATOM   821  C  CA  . ALA A  1 121 ? 23.77196 -21.06261 -9.62578  1.000 18.12104 ? 152  ALA A CA  1 
ATOM   822  C  C   . ALA A  1 121 ? 22.53877 -20.85426 -8.76381  1.000 19.15092 ? 152  ALA A C   1 
ATOM   823  O  O   . ALA A  1 121 ? 21.61931 -21.67655 -8.77925  1.000 18.61141 ? 152  ALA A O   1 
ATOM   824  C  CB  . ALA A  1 121 ? 23.46032 -20.66369 -11.08012 1.000 19.31435 ? 152  ALA A CB  1 
ATOM   825  N  N   . ILE A  1 122 ? 22.51318 -19.74899 -8.02025  1.000 17.44446 ? 153  ILE A N   1 
ATOM   826  C  CA  . ILE A  1 122 ? 21.43042 -19.45397 -7.08757  1.000 16.27891 ? 153  ILE A CA  1 
ATOM   827  C  C   . ILE A  1 122 ? 21.04469 -17.99596 -7.25710  1.000 18.84274 ? 153  ILE A C   1 
ATOM   828  O  O   . ILE A  1 122 ? 21.91884 -17.12329 -7.32094  1.000 18.14740 ? 153  ILE A O   1 
ATOM   829  C  CB  . ILE A  1 122 ? 21.84879 -19.72002 -5.62872  1.000 14.66719 ? 153  ILE A CB  1 
ATOM   830  C  CG1 . ILE A  1 122 ? 22.27280 -21.17207 -5.44042  1.000 17.39832 ? 153  ILE A CG1 1 
ATOM   831  C  CG2 . ILE A  1 122 ? 20.73455 -19.34625 -4.65041  1.000 16.10945 ? 153  ILE A CG2 1 
ATOM   832  C  CD1 . ILE A  1 122 ? 23.09986 -21.37301 -4.20342  1.000 19.82215 ? 153  ILE A CD1 1 
ATOM   833  N  N   . GLY A  1 123 ? 19.74855 -17.73135 -7.33380  1.000 16.82460 ? 154  GLY A N   1 
ATOM   834  C  CA  . GLY A  1 123 ? 19.24221 -16.36931 -7.29488  1.000 16.03992 ? 154  GLY A CA  1 
ATOM   835  C  C   . GLY A  1 123 ? 18.97679 -15.82048 -8.69277  1.000 16.43797 ? 154  GLY A C   1 
ATOM   836  O  O   . GLY A  1 123 ? 18.32334 -16.47006 -9.51040  1.000 19.47257 ? 154  GLY A O   1 
ATOM   837  N  N   . LYS A  1 124 ? 19.48378 -14.61802 -8.95739  1.000 16.65305 ? 155  LYS A N   1 
ATOM   838  C  CA  . LYS A  1 124 ? 19.16021 -13.88127 -10.17193 1.000 16.69922 ? 155  LYS A CA  1 
ATOM   839  C  C   . LYS A  1 124 ? 19.98695 -14.34917 -11.36655 1.000 17.46519 ? 155  LYS A C   1 
ATOM   840  O  O   . LYS A  1 124 ? 21.19337 -14.57905 -11.25367 1.000 19.29931 ? 155  LYS A O   1 
ATOM   841  C  CB  . LYS A  1 124 ? 19.40028 -12.39106 -9.92647  1.000 16.45493 ? 155  LYS A CB  1 
ATOM   842  C  CG  . LYS A  1 124 ? 19.36578 -11.51743 -11.17399 1.000 17.65216 ? 155  LYS A CG  1 
ATOM   843  C  CD  . LYS A  1 124 ? 19.26615 -10.05529 -10.76943 1.000 16.41291 ? 155  LYS A CD  1 
ATOM   844  C  CE  . LYS A  1 124 ? 19.54196 -9.12025  -11.94972 1.000 18.51111 ? 155  LYS A CE  1 
ATOM   845  N  NZ  . LYS A  1 124 ? 19.19661 -7.70366  -11.62979 1.000 18.71739 ? 155  LYS A NZ  1 
ATOM   846  N  N   . TRP A  1 125 ? 19.33433 -14.44833 -12.53213 1.000 17.15035 ? 156  TRP A N   1 
ATOM   847  C  CA  . TRP A  1 125 ? 20.02140 -14.84289 -13.76475 1.000 18.25743 ? 156  TRP A CA  1 
ATOM   848  C  C   . TRP A  1 125 ? 20.20824 -13.63344 -14.67217 1.000 18.37796 ? 156  TRP A C   1 
ATOM   849  O  O   . TRP A  1 125 ? 21.29826 -13.04833 -14.72041 1.000 18.65025 ? 156  TRP A O   1 
ATOM   850  C  CB  . TRP A  1 125 ? 19.22622 -15.95162 -14.47517 1.000 17.36746 ? 156  TRP A CB  1 
ATOM   851  C  CG  . TRP A  1 125 ? 19.90520 -16.63042 -15.65800 1.000 18.62306 ? 156  TRP A CG  1 
ATOM   852  C  CD1 . TRP A  1 125 ? 19.40972 -16.75792 -16.92342 1.000 19.37151 ? 156  TRP A CD1 1 
ATOM   853  C  CD2 . TRP A  1 125 ? 21.15781 -17.32423 -15.64744 1.000 17.33292 ? 156  TRP A CD2 1 
ATOM   854  N  NE1 . TRP A  1 125 ? 20.28290 -17.48995 -17.70647 1.000 20.87752 ? 156  TRP A NE1 1 
ATOM   855  C  CE2 . TRP A  1 125 ? 21.36381 -17.84574 -16.94446 1.000 18.33644 ? 156  TRP A CE2 1 
ATOM   856  C  CE3 . TRP A  1 125 ? 22.12910 -17.55872 -14.66622 1.000 18.04746 ? 156  TRP A CE3 1 
ATOM   857  C  CZ2 . TRP A  1 125 ? 22.49728 -18.58703 -17.27978 1.000 18.45141 ? 156  TRP A CZ2 1 
ATOM   858  C  CZ3 . TRP A  1 125 ? 23.25797 -18.28632 -15.01021 1.000 20.37395 ? 156  TRP A CZ3 1 
ATOM   859  C  CH2 . TRP A  1 125 ? 23.43059 -18.79218 -16.30349 1.000 21.94734 ? 156  TRP A CH2 1 
ATOM   860  N  N   . HIS A  1 126 ? 19.14743 -13.25489 -15.38963 1.000 17.25091 ? 157  HIS A N   1 
ATOM   861  C  CA  . HIS A  1 126 ? 19.09334 -12.06710 -16.23891 1.000 17.43399 ? 157  HIS A CA  1 
ATOM   862  C  C   . HIS A  1 126 ? 19.91183 -12.22829 -17.51153 1.000 18.21955 ? 157  HIS A C   1 
ATOM   863  O  O   . HIS A  1 126 ? 20.26812 -11.23554 -18.14801 1.000 20.32333 ? 157  HIS A O   1 
ATOM   864  C  CB  . HIS A  1 126 ? 19.53576 -10.80018 -15.48489 1.000 18.62446 ? 157  HIS A CB  1 
ATOM   865  C  CG  . HIS A  1 126 ? 18.81316 -9.55904  -15.91332 1.000 18.53635 ? 157  HIS A CG  1 
ATOM   866  N  ND1 . HIS A  1 126 ? 19.17588 -8.29852  -15.48571 1.000 19.05664 ? 157  HIS A ND1 1 
ATOM   867  C  CD2 . HIS A  1 126 ? 17.73382 -9.39039  -16.71255 1.000 18.56150 ? 157  HIS A CD2 1 
ATOM   868  C  CE1 . HIS A  1 126 ? 18.35381 -7.40638  -16.00997 1.000 21.77795 ? 157  HIS A CE1 1 
ATOM   869  N  NE2 . HIS A  1 126 ? 17.47153 -8.04162  -16.75918 1.000 22.10515 ? 157  HIS A NE2 1 
ATOM   870  N  N   . LEU A  1 127 ? 20.16455 -13.47386 -17.92227 1.000 18.36721 ? 158  LEU A N   1 
ATOM   871  C  CA  . LEU A  1 127 ? 20.99726 -13.75871 -19.08223 1.000 16.05894 ? 158  LEU A CA  1 
ATOM   872  C  C   . LEU A  1 127 ? 20.21765 -14.47353 -20.18070 1.000 18.80698 ? 158  LEU A C   1 
ATOM   873  O  O   . LEU A  1 127 ? 20.82279 -15.02589 -21.10667 1.000 19.21286 ? 158  LEU A O   1 
ATOM   874  C  CB  . LEU A  1 127 ? 22.21941 -14.57839 -18.66802 1.000 18.33422 ? 158  LEU A CB  1 
ATOM   875  C  CG  . LEU A  1 127 ? 23.07270 -13.86738 -17.61730 1.000 18.76495 ? 158  LEU A CG  1 
ATOM   876  C  CD1 . LEU A  1 127 ? 24.20625 -14.76888 -17.19650 1.000 20.23349 ? 158  LEU A CD1 1 
ATOM   877  C  CD2 . LEU A  1 127 ? 23.62335 -12.55214 -18.15897 1.000 18.82944 ? 158  LEU A CD2 1 
ATOM   878  N  N   . GLY A  1 128 ? 18.89179 -14.45963 -20.09846 1.000 18.53255 ? 159  GLY A N   1 
ATOM   879  C  CA  . GLY A  1 128 ? 18.04956 -15.09671 -21.09690 1.000 19.44910 ? 159  GLY A CA  1 
ATOM   880  C  C   . GLY A  1 128 ? 17.02895 -16.01683 -20.45715 1.000 18.24528 ? 159  GLY A C   1 
ATOM   881  O  O   . GLY A  1 128 ? 17.38195 -16.82178 -19.58842 1.000 21.19032 ? 159  GLY A O   1 
ATOM   882  N  N   . ALA A  1 129 ? 15.76408 -15.92203 -20.88398 1.000 20.45173 ? 160  ALA A N   1 
ATOM   883  C  CA  . ALA A  1 129 ? 14.67666 -16.69089 -20.28499 1.000 20.10440 ? 160  ALA A CA  1 
ATOM   884  C  C   . ALA A  1 129 ? 14.18254 -17.81566 -21.18311 1.000 22.91119 ? 160  ALA A C   1 
ATOM   885  O  O   . ALA A  1 129 ? 13.23549 -18.52103 -20.81181 1.000 25.57846 ? 160  ALA A O   1 
ATOM   886  C  CB  . ALA A  1 129 ? 13.49989 -15.77372 -19.92851 1.000 22.68827 ? 160  ALA A CB  1 
ATOM   887  N  N   . ALA A  1 130 ? 14.78819 -18.00267 -22.32631 1.000 21.65763 ? 161  ALA A N   1 
ATOM   888  C  CA  . ALA A  1 130 ? 14.44808 -19.09367 -23.22737 1.000 24.31622 ? 161  ALA A CA  1 
ATOM   889  C  C   . ALA A  1 130 ? 15.29004 -20.31860 -22.89753 1.000 25.37931 ? 161  ALA A C   1 
ATOM   890  O  O   . ALA A  1 130 ? 16.35880 -20.20274 -22.28971 1.000 22.17671 ? 161  ALA A O   1 
ATOM   891  C  CB  . ALA A  1 130 ? 14.66359 -18.65414 -24.67808 1.000 23.98686 ? 161  ALA A CB  1 
ATOM   892  N  N   . PRO A  1 131 ? 14.82583 -21.52019 -23.26331 1.000 24.57047 ? 162  PRO A N   1 
ATOM   893  C  CA  . PRO A  1 131 ? 15.51310 -22.74228 -22.79457 1.000 25.12973 ? 162  PRO A CA  1 
ATOM   894  C  C   . PRO A  1 131 ? 16.99669 -22.82077 -23.13063 1.000 22.54882 ? 162  PRO A C   1 
ATOM   895  O  O   . PRO A  1 131 ? 17.78169 -23.30718 -22.30574 1.000 23.46657 ? 162  PRO A O   1 
ATOM   896  C  CB  . PRO A  1 131 ? 14.72060 -23.86472 -23.48249 1.000 25.46636 ? 162  PRO A CB  1 
ATOM   897  C  CG  . PRO A  1 131 ? 13.34897 -23.30649 -23.61190 1.000 27.51669 ? 162  PRO A CG  1 
ATOM   898  C  CD  . PRO A  1 131 ? 13.50652 -21.81729 -23.85576 1.000 25.06648 ? 162  PRO A CD  1 
ATOM   899  N  N   . LYS A  1 132 ? 17.42156 -22.36006 -24.31019 1.000 22.68822 ? 163  LYS A N   1 
ATOM   900  C  CA  . LYS A  1 132 ? 18.83169 -22.50588 -24.64883 1.000 21.98868 ? 163  LYS A CA  1 
ATOM   901  C  C   . LYS A  1 132 ? 19.73073 -21.59744 -23.82104 1.000 21.58085 ? 163  LYS A C   1 
ATOM   902  O  O   . LYS A  1 132 ? 20.95289 -21.79650 -23.81339 1.000 22.14860 ? 163  LYS A O   1 
ATOM   903  C  CB  . LYS A  1 132 ? 19.06211 -22.24669 -26.13746 1.000 25.02080 ? 163  LYS A CB  1 
ATOM   904  C  CG  . LYS A  1 132 ? 18.82842 -20.82710 -26.61119 1.000 27.24613 ? 163  LYS A CG  1 
ATOM   905  C  CD  . LYS A  1 132 ? 19.33951 -20.70934 -28.04042 1.000 31.48067 ? 163  LYS A CD  1 
ATOM   906  C  CE  . LYS A  1 132 ? 18.63690 -19.62617 -28.80157 1.000 35.56520 ? 163  LYS A CE  1 
ATOM   907  N  NZ  . LYS A  1 132 ? 19.03870 -19.66676 -30.24816 1.000 35.07403 ? 163  LYS A NZ  1 
ATOM   908  N  N   . PHE A  1 133 ? 19.15364 -20.63651 -23.11243 1.000 19.50474 ? 164  PHE A N   1 
ATOM   909  C  CA  . PHE A  1 133 ? 19.91307 -19.73330 -22.25732 1.000 18.74614 ? 164  PHE A CA  1 
ATOM   910  C  C   . PHE A  1 133 ? 19.86311 -20.14255 -20.79461 1.000 24.10715 ? 164  PHE A C   1 
ATOM   911  O  O   . PHE A  1 133 ? 20.43316 -19.44976 -19.95011 1.000 21.27393 ? 164  PHE A O   1 
ATOM   912  C  CB  . PHE A  1 133 ? 19.37148 -18.30567 -22.41328 1.000 20.53487 ? 164  PHE A CB  1 
ATOM   913  C  CG  . PHE A  1 133 ? 19.38536 -17.80403 -23.83026 1.000 21.34217 ? 164  PHE A CG  1 
ATOM   914  C  CD1 . PHE A  1 133 ? 20.58182 -17.66205 -24.51473 1.000 18.85895 ? 164  PHE A CD1 1 
ATOM   915  C  CD2 . PHE A  1 133 ? 18.19812 -17.44472 -24.47268 1.000 22.35922 ? 164  PHE A CD2 1 
ATOM   916  C  CE1 . PHE A  1 133 ? 20.60640 -17.19429 -25.81592 1.000 21.58523 ? 164  PHE A CE1 1 
ATOM   917  C  CE2 . PHE A  1 133 ? 18.22337 -16.96521 -25.78400 1.000 21.18120 ? 164  PHE A CE2 1 
ATOM   918  C  CZ  . PHE A  1 133 ? 19.43367 -16.84398 -26.44883 1.000 21.44140 ? 164  PHE A CZ  1 
ATOM   919  N  N   . HIS A  1 134 ? 19.20534 -21.24823 -20.48096 1.000 20.24183 ? 165  HIS A N   1 
ATOM   920  C  CA  . HIS A  1 134 ? 18.95470 -21.62254 -19.09602 1.000 21.56959 ? 165  HIS A CA  1 
ATOM   921  C  C   . HIS A  1 134 ? 20.25171 -22.02843 -18.39040 1.000 20.53147 ? 165  HIS A C   1 
ATOM   922  O  O   . HIS A  1 134 ? 21.14110 -22.61322 -19.00708 1.000 20.80918 ? 165  HIS A O   1 
ATOM   923  C  CB  . HIS A  1 134 ? 17.96017 -22.78201 -19.05741 1.000 21.70740 ? 165  HIS A CB  1 
ATOM   924  C  CG  . HIS A  1 134 ? 17.47726 -23.12453 -17.68817 1.000 20.18790 ? 165  HIS A CG  1 
ATOM   925  N  ND1 . HIS A  1 134 ? 18.22872 -23.86078 -16.79497 1.000 20.51712 ? 165  HIS A ND1 1 
ATOM   926  C  CD2 . HIS A  1 134 ? 16.31912 -22.82447 -17.05292 1.000 22.27715 ? 165  HIS A CD2 1 
ATOM   927  C  CE1 . HIS A  1 134 ? 17.54891 -24.00185 -15.67049 1.000 20.20386 ? 165  HIS A CE1 1 
ATOM   928  N  NE2 . HIS A  1 134 ? 16.38572 -23.38981 -15.80456 1.000 21.41414 ? 165  HIS A NE2 1 
ATOM   929  N  N   . PRO A  1 135 ? 20.38101 -21.72408 -17.08875 1.000 19.78214 ? 166  PRO A N   1 
ATOM   930  C  CA  . PRO A  1 135 ? 21.58021 -22.15302 -16.33891 1.000 19.13241 ? 166  PRO A CA  1 
ATOM   931  C  C   . PRO A  1 135 ? 21.98639 -23.60834 -16.54048 1.000 20.81502 ? 166  PRO A C   1 
ATOM   932  O  O   . PRO A  1 135 ? 23.18297 -23.89693 -16.67445 1.000 20.35300 ? 166  PRO A O   1 
ATOM   933  C  CB  . PRO A  1 135 ? 21.17148 -21.88419 -14.88259 1.000 19.04269 ? 166  PRO A CB  1 
ATOM   934  C  CG  . PRO A  1 135 ? 20.28586 -20.66020 -14.99059 1.000 18.07753 ? 166  PRO A CG  1 
ATOM   935  C  CD  . PRO A  1 135 ? 19.49756 -20.86805 -16.27475 1.000 19.86214 ? 166  PRO A CD  1 
ATOM   936  N  N   . ASN A  1 136 ? 21.02995 -24.54055 -16.56124 1.000 19.60569 ? 167  ASN A N   1 
ATOM   937  C  CA  . ASN A  1 136 ? 21.38455 -25.94790 -16.71882 1.000 24.17916 ? 167  ASN A CA  1 
ATOM   938  C  C   . ASN A  1 136 ? 21.98323 -26.25984 -18.08319 1.000 24.27510 ? 167  ASN A C   1 
ATOM   939  O  O   . ASN A  1 136 ? 22.67058 -27.27707 -18.21741 1.000 26.14512 ? 167  ASN A O   1 
ATOM   940  C  CB  . ASN A  1 136 ? 20.16753 -26.84808 -16.50844 1.000 22.55675 ? 167  ASN A CB  1 
ATOM   941  C  CG  . ASN A  1 136 ? 19.64613 -26.82674 -15.09332 1.000 22.54281 ? 167  ASN A CG  1 
ATOM   942  O  OD1 . ASN A  1 136 ? 18.43454 -26.87317 -14.88720 1.000 22.56957 ? 167  ASN A OD1 1 
ATOM   943  N  ND2 . ASN A  1 136 ? 20.54713 -26.77305 -14.10654 1.000 20.63656 ? 167  ASN A ND2 1 
ATOM   944  N  N   . LYS A  1 137 ? 21.71187 -25.44124 -19.09988 1.000 21.45621 ? 168  LYS A N   1 
ATOM   945  C  CA  . LYS A  1 137 ? 22.35904 -25.58793 -20.39819 1.000 22.45618 ? 168  LYS A CA  1 
ATOM   946  C  C   . LYS A  1 137 ? 23.66057 -24.80449 -20.50015 1.000 27.38191 ? 168  LYS A C   1 
ATOM   947  O  O   . LYS A  1 137 ? 24.36189 -24.92646 -21.51215 1.000 25.86049 ? 168  LYS A O   1 
ATOM   948  C  CB  . LYS A  1 137 ? 21.42184 -25.12487 -21.52200 1.000 24.22359 ? 168  LYS A CB  1 
ATOM   949  C  CG  . LYS A  1 137 ? 20.12242 -25.89999 -21.65688 1.000 28.34901 ? 168  LYS A CG  1 
ATOM   950  C  CD  . LYS A  1 137 ? 20.32964 -27.25041 -22.31738 1.000 36.28293 ? 168  LYS A CD  1 
ATOM   951  C  CE  . LYS A  1 137 ? 18.99532 -27.80056 -22.80853 1.000 40.92496 ? 168  LYS A CE  1 
ATOM   952  N  NZ  . LYS A  1 137 ? 19.07933 -29.23847 -23.19294 1.000 49.73466 ? 168  LYS A NZ  1 
ATOM   953  N  N   . ARG A  1 138 ? 23.99128 -23.99294 -19.48830 1.000 22.71275 ? 169  ARG A N   1 
ATOM   954  C  CA  . ARG A  1 138 ? 25.16372 -23.12409 -19.51539 1.000 24.04328 ? 169  ARG A CA  1 
ATOM   955  C  C   . ARG A  1 138 ? 26.15741 -23.49439 -18.41964 1.000 23.17734 ? 169  ARG A C   1 
ATOM   956  O  O   . ARG A  1 138 ? 26.82380 -22.61535 -17.86457 1.000 22.59370 ? 169  ARG A O   1 
ATOM   957  C  CB  . ARG A  1 138 ? 24.78755 -21.64962 -19.35724 1.000 22.80624 ? 169  ARG A CB  1 
ATOM   958  C  CG  . ARG A  1 138 ? 23.62189 -21.09254 -20.17948 1.000 29.15169 ? 169  ARG A CG  1 
ATOM   959  C  CD  . ARG A  1 138 ? 23.91101 -20.89413 -21.65697 1.000 29.02021 ? 169  ARG A CD  1 
ATOM   960  N  NE  . ARG A  1 138 ? 25.15982 -20.22547 -21.99988 1.000 21.47659 ? 169  ARG A NE  1 
ATOM   961  C  CZ  . ARG A  1 138 ? 25.25885 -19.16591 -22.79247 1.000 18.73793 ? 169  ARG A CZ  1 
ATOM   962  N  NH1 . ARG A  1 138 ? 24.20967 -18.39932 -23.06323 1.000 20.55740 ? 169  ARG A NH1 1 
ATOM   963  N  NH2 . ARG A  1 138 ? 26.43184 -18.89057 -23.35968 1.000 22.04497 ? 169  ARG A NH2 1 
ATOM   964  N  N   . GLY A  1 139 ? 26.24828 -24.77672 -18.07738 1.000 22.36935 ? 170  GLY A N   1 
ATOM   965  C  CA  . GLY A  1 139 ? 27.30850 -25.26225 -17.22340 1.000 20.90523 ? 170  GLY A CA  1 
ATOM   966  C  C   . GLY A  1 139 ? 26.99067 -25.37248 -15.75012 1.000 21.35082 ? 170  GLY A C   1 
ATOM   967  O  O   . GLY A  1 139 ? 27.91279 -25.60203 -14.95957 1.000 22.67304 ? 170  GLY A O   1 
ATOM   968  N  N   . PHE A  1 140 ? 25.72766 -25.23578 -15.35118 1.000 21.41929 ? 171  PHE A N   1 
ATOM   969  C  CA  . PHE A  1 140 ? 25.34401 -25.32177 -13.94662 1.000 19.13786 ? 171  PHE A CA  1 
ATOM   970  C  C   . PHE A  1 140 ? 24.61275 -26.63168 -13.67581 1.000 21.56865 ? 171  PHE A C   1 
ATOM   971  O  O   . PHE A  1 140 ? 23.52069 -26.85649 -14.20565 1.000 23.35611 ? 171  PHE A O   1 
ATOM   972  C  CB  . PHE A  1 140 ? 24.48411 -24.12323 -13.54993 1.000 19.86240 ? 171  PHE A CB  1 
ATOM   973  C  CG  . PHE A  1 140 ? 25.27945 -22.86124 -13.37537 1.000 19.23241 ? 171  PHE A CG  1 
ATOM   974  C  CD1 . PHE A  1 140 ? 26.08752 -22.69147 -12.25763 1.000 18.19543 ? 171  PHE A CD1 1 
ATOM   975  C  CD2 . PHE A  1 140 ? 25.24918 -21.86201 -14.34391 1.000 19.04839 ? 171  PHE A CD2 1 
ATOM   976  C  CE1 . PHE A  1 140 ? 26.83326 -21.52071 -12.08566 1.000 19.13264 ? 171  PHE A CE1 1 
ATOM   977  C  CE2 . PHE A  1 140 ? 25.99055 -20.69184 -14.18173 1.000 17.68664 ? 171  PHE A CE2 1 
ATOM   978  C  CZ  . PHE A  1 140 ? 26.78021 -20.52235 -13.04432 1.000 18.20174 ? 171  PHE A CZ  1 
ATOM   979  N  N   . ASP A  1 141 ? 25.20601 -27.47772 -12.82288 1.000 19.98972 ? 172  ASP A N   1 
ATOM   980  C  CA  . ASP A  1 141 ? 24.52929 -28.70936 -12.41039 1.000 19.71077 ? 172  ASP A CA  1 
ATOM   981  C  C   . ASP A  1 141 ? 23.20731 -28.40200 -11.71758 1.000 22.79098 ? 172  ASP A C   1 
ATOM   982  O  O   . ASP A  1 141 ? 22.20556 -29.09419 -11.92755 1.000 22.00071 ? 172  ASP A O   1 
ATOM   983  C  CB  . ASP A  1 141 ? 25.43180 -29.52894 -11.47734 1.000 21.04023 ? 172  ASP A CB  1 
ATOM   984  C  CG  . ASP A  1 141 ? 26.67772 -30.05914 -12.16177 1.000 24.17662 ? 172  ASP A CG  1 
ATOM   985  O  OD1 . ASP A  1 141 ? 26.58193 -30.54243 -13.31310 1.000 26.67949 ? 172  ASP A OD1 1 
ATOM   986  O  OD2 . ASP A  1 141 ? 27.76191 -30.01749 -11.53101 1.000 24.15770 ? 172  ASP A OD2 1 
ATOM   987  N  N   . ASP A  1 142 ? 23.18126 -27.36909 -10.87869 1.000 19.19468 ? 173  ASP A N   1 
ATOM   988  C  CA  . ASP A  1 142 ? 21.98247 -27.01295 -10.14063 1.000 19.21883 ? 173  ASP A CA  1 
ATOM   989  C  C   . ASP A  1 142 ? 21.69342 -25.54124 -10.35978 1.000 22.88619 ? 173  ASP A C   1 
ATOM   990  O  O   . ASP A  1 142 ? 22.62096 -24.73280 -10.44346 1.000 20.51076 ? 173  ASP A O   1 
ATOM   991  C  CB  . ASP A  1 142 ? 22.13348 -27.28486 -8.64180  1.000 22.03379 ? 173  ASP A CB  1 
ATOM   992  C  CG  . ASP A  1 142 ? 20.80461 -27.24887 -7.90782  1.000 27.64592 ? 173  ASP A CG  1 
ATOM   993  O  OD1 . ASP A  1 142 ? 20.38954 -26.16334 -7.42990  1.000 31.53626 ? 173  ASP A OD1 1 
ATOM   994  O  OD2 . ASP A  1 142 ? 20.15424 -28.30930 -7.82563  1.000 31.70954 ? 173  ASP A OD2 1 
ATOM   995  N  N   . PHE A  1 143 ? 20.40892 -25.20573 -10.47738 1.000 20.05903 ? 174  PHE A N   1 
ATOM   996  C  CA  . PHE A  1 143 ? 19.96305 -23.81834 -10.49670 1.000 19.67529 ? 174  PHE A CA  1 
ATOM   997  C  C   . PHE A  1 143 ? 18.75847 -23.69006 -9.58450  1.000 20.78112 ? 174  PHE A C   1 
ATOM   998  O  O   . PHE A  1 143 ? 17.83235 -24.50613 -9.65339  1.000 20.92984 ? 174  PHE A O   1 
ATOM   999  C  CB  . PHE A  1 143 ? 19.60215 -23.33905 -11.90853 1.000 19.27607 ? 174  PHE A CB  1 
ATOM   1000 C  CG  . PHE A  1 143 ? 18.98430 -21.96149 -11.94100 1.000 19.13326 ? 174  PHE A CG  1 
ATOM   1001 C  CD1 . PHE A  1 143 ? 19.67169 -20.86104 -11.43200 1.000 19.08157 ? 174  PHE A CD1 1 
ATOM   1002 C  CD2 . PHE A  1 143 ? 17.72841 -21.76015 -12.48532 1.000 20.65067 ? 174  PHE A CD2 1 
ATOM   1003 C  CE1 . PHE A  1 143 ? 19.10315 -19.60325 -11.45687 1.000 19.06288 ? 174  PHE A CE1 1 
ATOM   1004 C  CE2 . PHE A  1 143 ? 17.15103 -20.48739 -12.52080 1.000 20.17268 ? 174  PHE A CE2 1 
ATOM   1005 C  CZ  . PHE A  1 143 ? 17.84377 -19.40323 -12.00791 1.000 18.75792 ? 174  PHE A CZ  1 
ATOM   1006 N  N   . TYR A  1 144 ? 18.78348 -22.68251 -8.71837  1.000 18.62149 ? 175  TYR A N   1 
ATOM   1007 C  CA  . TYR A  1 144 ? 17.64167 -22.34301 -7.87717  1.000 18.41233 ? 175  TYR A CA  1 
ATOM   1008 C  C   . TYR A  1 144 ? 17.47890 -20.83502 -7.93658  1.000 18.96450 ? 175  TYR A C   1 
ATOM   1009 O  O   . TYR A  1 144 ? 18.34120 -20.10825 -7.44298  1.000 18.95211 ? 175  TYR A O   1 
ATOM   1010 C  CB  . TYR A  1 144 ? 17.85228 -22.79470 -6.43062  1.000 19.06217 ? 175  TYR A CB  1 
ATOM   1011 C  CG  . TYR A  1 144 ? 16.63232 -22.57425 -5.56038  1.000 20.21229 ? 175  TYR A CG  1 
ATOM   1012 C  CD1 . TYR A  1 144 ? 16.36797 -21.32488 -4.99715  1.000 20.49514 ? 175  TYR A CD1 1 
ATOM   1013 C  CD2 . TYR A  1 144 ? 15.72930 -23.61160 -5.31874  1.000 21.34589 ? 175  TYR A CD2 1 
ATOM   1014 C  CE1 . TYR A  1 144 ? 15.24992 -21.11207 -4.21702  1.000 21.57655 ? 175  TYR A CE1 1 
ATOM   1015 C  CE2 . TYR A  1 144 ? 14.60086 -23.40789 -4.52593  1.000 24.70623 ? 175  TYR A CE2 1 
ATOM   1016 C  CZ  . TYR A  1 144 ? 14.37119 -22.15543 -3.97923  1.000 23.93330 ? 175  TYR A CZ  1 
ATOM   1017 O  OH  . TYR A  1 144 ? 13.25411 -21.92729 -3.20115  1.000 24.16951 ? 175  TYR A OH  1 
ATOM   1018 N  N   . GLY A  1 145 ? 16.38085 -20.35826 -8.50721  1.000 17.82594 ? 176  GLY A N   1 
ATOM   1019 C  CA  . GLY A  1 145 ? 16.23470 -18.90552 -8.55215  1.000 16.29230 ? 176  GLY A CA  1 
ATOM   1020 C  C   . GLY A  1 145 ? 15.24980 -18.49055 -9.62585  1.000 19.81432 ? 176  GLY A C   1 
ATOM   1021 O  O   . GLY A  1 145 ? 14.27042 -19.19153 -9.88758  1.000 20.60796 ? 176  GLY A O   1 
ATOM   1022 N  N   . PHE A  1 146 ? 15.52337 -17.32745 -10.22557 1.000 17.56968 ? 177  PHE A N   1 
ATOM   1023 C  CA  . PHE A  1 146 ? 14.62415 -16.75196 -11.21861 1.000 17.03041 ? 177  PHE A CA  1 
ATOM   1024 C  C   . PHE A  1 146 ? 15.41165 -16.27290 -12.43009 1.000 21.67787 ? 177  PHE A C   1 
ATOM   1025 O  O   . PHE A  1 146 ? 16.57560 -15.87043 -12.32125 1.000 20.67671 ? 177  PHE A O   1 
ATOM   1026 C  CB  . PHE A  1 146 ? 13.78288 -15.60769 -10.62197 1.000 18.85663 ? 177  PHE A CB  1 
ATOM   1027 C  CG  . PHE A  1 146 ? 14.59316 -14.45902 -10.06573 1.000 16.94348 ? 177  PHE A CG  1 
ATOM   1028 C  CD1 . PHE A  1 146 ? 14.96274 -13.40409 -10.88142 1.000 16.93068 ? 177  PHE A CD1 1 
ATOM   1029 C  CD2 . PHE A  1 146 ? 14.94620 -14.42161 -8.71874  1.000 19.46131 ? 177  PHE A CD2 1 
ATOM   1030 C  CE1 . PHE A  1 146 ? 15.69025 -12.33243 -10.38856 1.000 18.81767 ? 177  PHE A CE1 1 
ATOM   1031 C  CE2 . PHE A  1 146 ? 15.68018 -13.34696 -8.21152  1.000 19.90110 ? 177  PHE A CE2 1 
ATOM   1032 C  CZ  . PHE A  1 146 ? 16.04535 -12.29959 -9.04414  1.000 18.66334 ? 177  PHE A CZ  1 
ATOM   1033 N  N   . LEU A  1 147 ? 14.76376 -16.32454 -13.60220 1.000 18.71946 ? 178  LEU A N   1 
ATOM   1034 C  CA  . LEU A  1 147 ? 15.49424 -16.07726 -14.84175 1.000 19.81742 ? 178  LEU A CA  1 
ATOM   1035 C  C   . LEU A  1 147 ? 15.61802 -14.60396 -15.20392 1.000 18.52041 ? 178  LEU A C   1 
ATOM   1036 O  O   . LEU A  1 147 ? 16.54679 -14.24991 -15.94001 1.000 19.11616 ? 178  LEU A O   1 
ATOM   1037 C  CB  . LEU A  1 147 ? 14.82899 -16.81619 -16.00132 1.000 19.65240 ? 178  LEU A CB  1 
ATOM   1038 C  CG  . LEU A  1 147 ? 14.85358 -18.33475 -15.84275 1.000 20.71823 ? 178  LEU A CG  1 
ATOM   1039 C  CD1 . LEU A  1 147 ? 13.98890 -18.98966 -16.92318 1.000 23.63128 ? 178  LEU A CD1 1 
ATOM   1040 C  CD2 . LEU A  1 147 ? 16.29289 -18.86100 -15.87216 1.000 21.98255 ? 178  LEU A CD2 1 
ATOM   1041 N  N   . GLY A  1 148 ? 14.72491 -13.74850 -14.71437 1.000 19.91706 ? 179  GLY A N   1 
ATOM   1042 C  CA  . GLY A  1 148 ? 14.66637 -12.35777 -15.12483 1.000 18.43654 ? 179  GLY A CA  1 
ATOM   1043 C  C   . GLY A  1 148 ? 15.54224 -11.43657 -14.29901 1.000 20.00150 ? 179  GLY A C   1 
ATOM   1044 O  O   . GLY A  1 148 ? 16.51902 -11.85326 -13.66670 1.000 19.56578 ? 179  GLY A O   1 
ATOM   1045 N  N   . GLY A  1 149 ? 15.16282 -10.15692 -14.30103 1.000 18.95688 ? 180  GLY A N   1 
ATOM   1046 C  CA  . GLY A  1 149 ? 15.95239 -9.08352  -13.72006 1.000 17.84585 ? 180  GLY A CA  1 
ATOM   1047 C  C   . GLY A  1 149 ? 15.69274 -8.76629  -12.26965 1.000 19.82201 ? 180  GLY A C   1 
ATOM   1048 O  O   . GLY A  1 149 ? 16.47595 -8.02818  -11.66135 1.000 20.07868 ? 180  GLY A O   1 
ATOM   1049 N  N   . GLY A  1 150 ? 14.61065 -9.27097  -11.69284 1.000 20.57686 ? 181  GLY A N   1 
ATOM   1050 C  CA  . GLY A  1 150 ? 14.35625 -8.97673  -10.29286 1.000 20.90289 ? 181  GLY A CA  1 
ATOM   1051 C  C   . GLY A  1 150 ? 13.20888 -9.81423  -9.78084  1.000 20.96647 ? 181  GLY A C   1 
ATOM   1052 O  O   . GLY A  1 150 ? 12.56505 -10.55483 -10.53120 1.000 20.58595 ? 181  GLY A O   1 
ATOM   1053 N  N   . HIS A  1 151 ? 12.95645 -9.69657  -8.47814  1.000 19.09478 ? 182  HIS A N   1 
ATOM   1054 C  CA  . HIS A  1 151 ? 11.88245 -10.49578 -7.90523  1.000 19.05735 ? 182  HIS A CA  1 
ATOM   1055 C  C   . HIS A  1 151 ? 11.41443 -9.88356  -6.59835  1.000 20.95503 ? 182  HIS A C   1 
ATOM   1056 O  O   . HIS A  1 151 ? 12.21898 -9.34610  -5.83780  1.000 21.91933 ? 182  HIS A O   1 
ATOM   1057 C  CB  . HIS A  1 151 ? 12.31115 -11.95106 -7.67015  1.000 20.52573 ? 182  HIS A CB  1 
ATOM   1058 C  CG  . HIS A  1 151 ? 11.16750 -12.91564 -7.73321  1.000 20.89805 ? 182  HIS A CG  1 
ATOM   1059 N  ND1 . HIS A  1 151 ? 10.28313 -13.08924 -6.69034  1.000 20.61159 ? 182  HIS A ND1 1 
ATOM   1060 C  CD2 . HIS A  1 151 ? 10.74038 -13.72700 -8.73035  1.000 21.11342 ? 182  HIS A CD2 1 
ATOM   1061 C  CE1 . HIS A  1 151 ? 9.36594  -13.97712 -7.03888  1.000 21.14664 ? 182  HIS A CE1 1 
ATOM   1062 N  NE2 . HIS A  1 151 ? 9.61859  -14.37874 -8.27200  1.000 22.03460 ? 182  HIS A NE2 1 
ATOM   1063 N  N   . ASP A  1 152 ? 10.11041 -9.98887  -6.33747  1.000 19.34509 ? 183  ASP A N   1 
ATOM   1064 C  CA  . ASP A  1 152 ? 9.59568  -9.63295  -5.02549  1.000 18.74348 ? 183  ASP A CA  1 
ATOM   1065 C  C   . ASP A  1 152 ? 10.13929 -10.60998 -3.98936  1.000 17.37329 ? 183  ASP A C   1 
ATOM   1066 O  O   . ASP A  1 152 ? 10.44240 -11.76825 -4.29640  1.000 20.04516 ? 183  ASP A O   1 
ATOM   1067 C  CB  . ASP A  1 152 ? 8.06346  -9.63561  -5.03103  1.000 21.18230 ? 183  ASP A CB  1 
ATOM   1068 C  CG  . ASP A  1 152 ? 7.47818  -8.46717  -5.81258  1.000 29.64945 ? 183  ASP A CG  1 
ATOM   1069 O  OD1 . ASP A  1 152 ? 8.25101  -7.65943  -6.37670  1.000 24.90104 ? 183  ASP A OD1 1 
ATOM   1070 O  OD2 . ASP A  1 152 ? 6.23356  -8.35536  -5.85941  1.000 31.17702 ? 183  ASP A OD2 1 
ATOM   1071 N  N   . TYR A  1 153 ? 10.24427 -10.14225 -2.74430  1.000 20.28808 ? 184  TYR A N   1 
ATOM   1072 C  CA  . TYR A  1 153 ? 11.04235 -10.84922 -1.74704  1.000 18.99042 ? 184  TYR A CA  1 
ATOM   1073 C  C   . TYR A  1 153 ? 10.25319 -11.80397 -0.85640  1.000 19.51179 ? 184  TYR A C   1 
ATOM   1074 O  O   . TYR A  1 153 ? 10.86274 -12.69210 -0.25432  1.000 20.43367 ? 184  TYR A O   1 
ATOM   1075 C  CB  . TYR A  1 153 ? 11.78796 -9.84626  -0.85555  1.000 19.01661 ? 184  TYR A CB  1 
ATOM   1076 C  CG  . TYR A  1 153 ? 13.00063 -9.19929  -1.51697  1.000 19.19033 ? 184  TYR A CG  1 
ATOM   1077 C  CD1 . TYR A  1 153 ? 12.85291 -8.11575  -2.38083  1.000 18.80913 ? 184  TYR A CD1 1 
ATOM   1078 C  CD2 . TYR A  1 153 ? 14.29112 -9.67012  -1.26442  1.000 17.64729 ? 184  TYR A CD2 1 
ATOM   1079 C  CE1 . TYR A  1 153 ? 13.95996 -7.52012  -2.97329  1.000 17.07874 ? 184  TYR A CE1 1 
ATOM   1080 C  CE2 . TYR A  1 153 ? 15.40237 -9.08424  -1.85549  1.000 18.31546 ? 184  TYR A CE2 1 
ATOM   1081 C  CZ  . TYR A  1 153 ? 15.22917 -8.01349  -2.70594  1.000 17.00895 ? 184  TYR A CZ  1 
ATOM   1082 O  OH  . TYR A  1 153 ? 16.33559 -7.43357  -3.28889  1.000 17.33681 ? 184  TYR A OH  1 
ATOM   1083 N  N   . PHE A  1 154 ? 8.93500  -11.65235 -0.74216  1.000 21.66423 ? 185  PHE A N   1 
ATOM   1084 C  CA  . PHE A  1 154 ? 8.17902  -12.46588 0.20836   1.000 21.18730 ? 185  PHE A CA  1 
ATOM   1085 C  C   . PHE A  1 154 ? 7.25861  -13.43341 -0.52221  1.000 22.49034 ? 185  PHE A C   1 
ATOM   1086 O  O   . PHE A  1 154 ? 6.29632  -12.99275 -1.16744  1.000 25.61097 ? 185  PHE A O   1 
ATOM   1087 C  CB  . PHE A  1 154 ? 7.37346  -11.57617 1.15287   1.000 21.88919 ? 185  PHE A CB  1 
ATOM   1088 C  CG  . PHE A  1 154 ? 8.20468  -10.90902 2.21017   1.000 22.82229 ? 185  PHE A CG  1 
ATOM   1089 C  CD1 . PHE A  1 154 ? 8.60524  -11.61522 3.33320   1.000 23.54236 ? 185  PHE A CD1 1 
ATOM   1090 C  CD2 . PHE A  1 154 ? 8.56990  -9.57679  2.09073   1.000 23.95971 ? 185  PHE A CD2 1 
ATOM   1091 C  CE1 . PHE A  1 154 ? 9.36667  -11.00404 4.32102   1.000 21.82064 ? 185  PHE A CE1 1 
ATOM   1092 C  CE2 . PHE A  1 154 ? 9.33412  -8.95997  3.07028   1.000 23.35114 ? 185  PHE A CE2 1 
ATOM   1093 C  CZ  . PHE A  1 154 ? 9.73434  -9.67829  4.18908   1.000 21.77096 ? 185  PHE A CZ  1 
ATOM   1094 N  N   . PRO A  1 155 ? 7.51630  -14.74459 -0.45343  1.000 21.92920 ? 186  PRO A N   1 
ATOM   1095 C  CA  . PRO A  1 155 ? 6.65097  -15.70709 -1.16154  1.000 20.80143 ? 186  PRO A CA  1 
ATOM   1096 C  C   . PRO A  1 155 ? 5.18975  -15.61968 -0.75873  1.000 26.21067 ? 186  PRO A C   1 
ATOM   1097 O  O   . PRO A  1 155 ? 4.31734  -15.76557 -1.62223  1.000 28.27478 ? 186  PRO A O   1 
ATOM   1098 C  CB  . PRO A  1 155 ? 7.25929  -17.06762 -0.78934  1.000 24.39850 ? 186  PRO A CB  1 
ATOM   1099 C  CG  . PRO A  1 155 ? 8.64216  -16.78039 -0.36686  1.000 29.91489 ? 186  PRO A CG  1 
ATOM   1100 C  CD  . PRO A  1 155 ? 8.63596  -15.40607 0.23824   1.000 24.64311 ? 186  PRO A CD  1 
ATOM   1101 N  N   . SER A  1 156 ? 4.88991  -15.38871 0.52326   1.000 27.01959 ? 187  SER A N   1 
ATOM   1102 C  CA  . SER A  1 156 ? 3.48995  -15.26611 0.92786   1.000 30.26982 ? 187  SER A CA  1 
ATOM   1103 C  C   . SER A  1 156 ? 2.78405  -14.12027 0.21502   1.000 33.36980 ? 187  SER A C   1 
ATOM   1104 O  O   . SER A  1 156 ? 1.55477  -14.14984 0.08066   1.000 32.64485 ? 187  SER A O   1 
ATOM   1105 C  CB  . SER A  1 156 ? 3.38355  -15.08466 2.44917   1.000 31.37455 ? 187  SER A CB  1 
ATOM   1106 O  OG  . SER A  1 156 ? 3.99035  -13.87702 2.87334   1.000 33.28623 ? 187  SER A OG  1 
ATOM   1107 N  N   . GLU A  1 157 ? 3.52909  -13.11407 -0.24551  1.000 27.56070 ? 188  GLU A N   1 
ATOM   1108 C  CA  . GLU A  1 157 ? 2.94973  -12.01840 -1.00730  1.000 28.78289 ? 188  GLU A CA  1 
ATOM   1109 C  C   . GLU A  1 157 ? 2.92500  -12.32367 -2.50077  1.000 28.53203 ? 188  GLU A C   1 
ATOM   1110 O  O   . GLU A  1 157 ? 1.86850  -12.23196 -3.13120  1.000 29.68918 ? 188  GLU A O   1 
ATOM   1111 C  CB  . GLU A  1 157 ? 3.71525  -10.71609 -0.73536  1.000 30.16376 ? 188  GLU A CB  1 
ATOM   1112 C  CG  . GLU A  1 157 ? 3.58970  -10.24054 0.70769   1.000 31.56949 ? 188  GLU A CG  1 
ATOM   1113 C  CD  . GLU A  1 157 ? 4.46707  -9.03911  1.04297   1.000 41.84065 ? 188  GLU A CD  1 
ATOM   1114 O  OE1 . GLU A  1 157 ? 5.29316  -8.62353  0.19807   1.000 32.05330 ? 188  GLU A OE1 1 
ATOM   1115 O  OE2 . GLU A  1 157 ? 4.32795  -8.50946  2.16801   1.000 46.94869 ? 188  GLU A OE2 1 
ATOM   1116 N  N   . TYR A  1 158 ? 4.06372  -12.71006 -3.08577  1.000 26.39614 ? 189  TYR A N   1 
ATOM   1117 C  CA  . TYR A  1 158 ? 4.08410  -12.81752 -4.54193  1.000 25.91135 ? 189  TYR A CA  1 
ATOM   1118 C  C   . TYR A  1 158 ? 3.36612  -14.06438 -5.04783  1.000 29.38715 ? 189  TYR A C   1 
ATOM   1119 O  O   . TYR A  1 158 ? 2.82677  -14.04269 -6.15960  1.000 27.13975 ? 189  TYR A O   1 
ATOM   1120 C  CB  . TYR A  1 158 ? 5.52597  -12.72650 -5.08405  1.000 25.99138 ? 189  TYR A CB  1 
ATOM   1121 C  CG  . TYR A  1 158 ? 6.50441  -13.86015 -4.80481  1.000 21.58697 ? 189  TYR A CG  1 
ATOM   1122 C  CD1 . TYR A  1 158 ? 6.36014  -15.11449 -5.39966  1.000 20.80461 ? 189  TYR A CD1 1 
ATOM   1123 C  CD2 . TYR A  1 158 ? 7.62999  -13.64040 -4.02520  1.000 22.21192 ? 189  TYR A CD2 1 
ATOM   1124 C  CE1 . TYR A  1 158 ? 7.26986  -16.14306 -5.16606  1.000 23.91564 ? 189  TYR A CE1 1 
ATOM   1125 C  CE2 . TYR A  1 158 ? 8.55287  -14.65494 -3.79360  1.000 21.92723 ? 189  TYR A CE2 1 
ATOM   1126 C  CZ  . TYR A  1 158 ? 8.36714  -15.90093 -4.36545  1.000 21.29657 ? 189  TYR A CZ  1 
ATOM   1127 O  OH  . TYR A  1 158 ? 9.28333  -16.90246 -4.14226  1.000 23.45083 ? 189  TYR A OH  1 
ATOM   1128 N  N   . GLN A  1 159 ? 3.33040  -15.14820 -4.26166  1.000 26.08773 ? 190  GLN A N   1 
ATOM   1129 C  CA  . GLN A  1 159 ? 2.59290  -16.33285 -4.69258  1.000 27.11330 ? 190  GLN A CA  1 
ATOM   1130 C  C   . GLN A  1 159 ? 1.09085  -16.07799 -4.66747  1.000 29.80258 ? 190  GLN A C   1 
ATOM   1131 O  O   . GLN A  1 159 ? 0.35950  -16.57460 -5.53079  1.000 31.72036 ? 190  GLN A O   1 
ATOM   1132 C  CB  . GLN A  1 159 ? 2.96004  -17.53595 -3.82044  1.000 28.60456 ? 190  GLN A CB  1 
ATOM   1133 C  CG  . GLN A  1 159 ? 4.37572  -18.04976 -4.04555  1.000 27.98237 ? 190  GLN A CG  1 
ATOM   1134 C  CD  . GLN A  1 159 ? 4.84341  -19.01209 -2.96329  1.000 31.32522 ? 190  GLN A CD  1 
ATOM   1135 O  OE1 . GLN A  1 159 ? 4.15664  -19.22940 -1.95993  1.000 33.55316 ? 190  GLN A OE1 1 
ATOM   1136 N  NE2 . GLN A  1 159 ? 6.02711  -19.58387 -3.15731  1.000 31.38438 ? 190  GLN A NE2 1 
ATOM   1137 N  N   . LYS A  1 160 ? 0.61323  -15.29750 -3.69415  1.000 30.40764 ? 191  LYS A N   1 
ATOM   1138 C  CA  . LYS A  1 160 ? -0.80167 -14.93280 -3.67793  1.000 31.26955 ? 191  LYS A CA  1 
ATOM   1139 C  C   . LYS A  1 160 ? -1.15651 -14.08365 -4.88965  1.000 34.48231 ? 191  LYS A C   1 
ATOM   1140 O  O   . LYS A  1 160 ? -2.18081 -14.31457 -5.54481  1.000 39.10096 ? 191  LYS A O   1 
ATOM   1141 C  CB  . LYS A  1 160 ? -1.13766 -14.19102 -2.38298  1.000 30.39092 ? 191  LYS A CB  1 
ATOM   1142 N  N   . THR A  1 161 ? -0.30392 -13.11073 -5.21635  1.000 30.24265 ? 192  THR A N   1 
ATOM   1143 C  CA  . THR A  1 161 ? -0.54882 -12.25470 -6.37128  1.000 28.73838 ? 192  THR A CA  1 
ATOM   1144 C  C   . THR A  1 161 ? -0.51817 -13.05514 -7.66446  1.000 32.91621 ? 192  THR A C   1 
ATOM   1145 O  O   . THR A  1 161 ? -1.40860 -12.92133 -8.51190  1.000 33.74076 ? 192  THR A O   1 
ATOM   1146 C  CB  . THR A  1 161 ? 0.49049  -11.13179 -6.41428  1.000 27.14330 ? 192  THR A CB  1 
ATOM   1147 O  OG1 . THR A  1 161 ? 0.33016  -10.28958 -5.26903  1.000 33.18150 ? 192  THR A OG1 1 
ATOM   1148 C  CG2 . THR A  1 161 ? 0.34092  -10.30586 -7.68452  1.000 31.19947 ? 192  THR A CG2 1 
ATOM   1149 N  N   . TYR A  1 162 ? 0.51299  -13.88476 -7.83982  1.000 30.18068 ? 193  TYR A N   1 
ATOM   1150 C  CA  . TYR A  1 162 ? 0.61178  -14.70594 -9.04209  1.000 28.45388 ? 193  TYR A CA  1 
ATOM   1151 C  C   . TYR A  1 162 ? -0.61370 -15.59932 -9.20024  1.000 33.11762 ? 193  TYR A C   1 
ATOM   1152 O  O   . TYR A  1 162 ? -1.18704 -15.70323 -10.29249 1.000 33.07169 ? 193  TYR A O   1 
ATOM   1153 C  CB  . TYR A  1 162 ? 1.88138  -15.55657 -8.99560  1.000 28.44860 ? 193  TYR A CB  1 
ATOM   1154 C  CG  . TYR A  1 162 ? 2.04379  -16.44777 -10.20032 1.000 31.24201 ? 193  TYR A CG  1 
ATOM   1155 C  CD1 . TYR A  1 162 ? 2.55868  -15.94480 -11.38924 1.000 29.12940 ? 193  TYR A CD1 1 
ATOM   1156 C  CD2 . TYR A  1 162 ? 1.67953  -17.79325 -10.15387 1.000 30.19715 ? 193  TYR A CD2 1 
ATOM   1157 C  CE1 . TYR A  1 162 ? 2.70591  -16.74776 -12.49661 1.000 28.78474 ? 193  TYR A CE1 1 
ATOM   1158 C  CE2 . TYR A  1 162 ? 1.83399  -18.61125 -11.26027 1.000 31.84413 ? 193  TYR A CE2 1 
ATOM   1159 C  CZ  . TYR A  1 162 ? 2.34359  -18.07904 -12.43077 1.000 31.73308 ? 193  TYR A CZ  1 
ATOM   1160 O  OH  . TYR A  1 162 ? 2.49855  -18.87700 -13.54500 1.000 35.85750 ? 193  TYR A OH  1 
ATOM   1161 N  N   . LYS A  1 163 ? -1.02269 -16.26300 -8.11541  1.000 33.46781 ? 194  LYS A N   1 
ATOM   1162 C  CA  . LYS A  1 163 ? -2.14374 -17.19506 -8.20002  1.000 34.08194 ? 194  LYS A CA  1 
ATOM   1163 C  C   . LYS A  1 163 ? -3.43775 -16.47212 -8.54050  1.000 35.50964 ? 194  LYS A C   1 
ATOM   1164 O  O   . LYS A  1 163 ? -4.22465 -16.94987 -9.36754  1.000 39.25760 ? 194  LYS A O   1 
ATOM   1165 C  CB  . LYS A  1 163 ? -2.28883 -17.96139 -6.88693  1.000 37.16538 ? 194  LYS A CB  1 
ATOM   1166 N  N   . ALA A  1 164 ? -3.67029 -15.31582 -7.91909  1.000 37.32000 ? 195  ALA A N   1 
ATOM   1167 C  CA  . ALA A  1 164 ? -4.88651 -14.55934 -8.19033  1.000 35.92314 ? 195  ALA A CA  1 
ATOM   1168 C  C   . ALA A  1 164 ? -4.91626 -14.05364 -9.62675  1.000 41.67519 ? 195  ALA A C   1 
ATOM   1169 O  O   . ALA A  1 164 ? -5.95647 -14.11716 -10.29431 1.000 40.18464 ? 195  ALA A O   1 
ATOM   1170 C  CB  . ALA A  1 164 ? -5.00196 -13.40029 -7.20427  1.000 35.53558 ? 195  ALA A CB  1 
ATOM   1171 N  N   . GLN A  1 165 ? -3.78309 -13.55879 -10.12654 1.000 35.96497 ? 196  GLN A N   1 
ATOM   1172 C  CA  . GLN A  1 165 ? -3.75654 -13.03643 -11.48709 1.000 37.76382 ? 196  GLN A CA  1 
ATOM   1173 C  C   . GLN A  1 165 ? -3.83695 -14.15141 -12.52157 1.000 34.12073 ? 196  GLN A C   1 
ATOM   1174 O  O   . GLN A  1 165 ? -4.41789 -13.95629 -13.59621 1.000 37.36456 ? 196  GLN A O   1 
ATOM   1175 C  CB  . GLN A  1 165 ? -2.50431 -12.18257 -11.68918 1.000 37.13678 ? 196  GLN A CB  1 
ATOM   1176 C  CG  . GLN A  1 165 ? -2.51659 -10.93099 -10.83371 1.000 37.57588 ? 196  GLN A CG  1 
ATOM   1177 C  CD  . GLN A  1 165 ? -1.32969 -10.02750 -11.08854 1.000 45.29395 ? 196  GLN A CD  1 
ATOM   1178 O  OE1 . GLN A  1 165 ? -0.34048 -10.44104 -11.69191 1.000 40.68505 ? 196  GLN A OE1 1 
ATOM   1179 N  NE2 . GLN A  1 165 ? -1.42270 -8.78135  -10.62857 1.000 47.02789 ? 196  GLN A NE2 1 
ATOM   1180 N  N   . LYS A  1 166 ? -3.27501 -15.32187 -12.21943 1.000 34.39604 ? 197  LYS A N   1 
ATOM   1181 C  CA  . LYS A  1 166 ? -3.40656 -16.46014 -13.12275 1.000 37.23410 ? 197  LYS A CA  1 
ATOM   1182 C  C   . LYS A  1 166 ? -4.86215 -16.89440 -13.23991 1.000 41.60991 ? 197  LYS A C   1 
ATOM   1183 O  O   . LYS A  1 166 ? -5.36737 -17.12606 -14.34429 1.000 39.72319 ? 197  LYS A O   1 
ATOM   1184 C  CB  . LYS A  1 166 ? -2.53500 -17.62093 -12.63863 1.000 39.12471 ? 197  LYS A CB  1 
ATOM   1185 N  N   . LYS A  1 167 ? -5.55496 -17.00616 -12.10400 1.000 43.93892 ? 198  LYS A N   1 
ATOM   1186 C  CA  . LYS A  1 167 ? -6.96091 -17.39835 -12.13319 1.000 45.89622 ? 198  LYS A CA  1 
ATOM   1187 C  C   . LYS A  1 167 ? -7.81300 -16.34652 -12.83182 1.000 45.88011 ? 198  LYS A C   1 
ATOM   1188 O  O   . LYS A  1 167 ? -8.74783 -16.68500 -13.56747 1.000 46.92840 ? 198  LYS A O   1 
ATOM   1189 C  CB  . LYS A  1 167 ? -7.46495 -17.64919 -10.71196 1.000 44.55766 ? 198  LYS A CB  1 
ATOM   1190 C  CG  . LYS A  1 167 ? -6.91590 -18.92692 -10.09756 1.000 42.78768 ? 198  LYS A CG  1 
ATOM   1191 C  CD  . LYS A  1 167 ? -7.14621 -18.97400 -8.59776  1.000 44.93010 ? 198  LYS A CD  1 
ATOM   1192 C  CE  . LYS A  1 167 ? -6.53431 -20.22786 -7.99883  1.000 48.78336 ? 198  LYS A CE  1 
ATOM   1193 N  NZ  . LYS A  1 167 ? -6.52567 -20.18492 -6.50975  1.000 46.99444 ? 198  LYS A NZ  1 
ATOM   1194 N  N   . ALA A  1 168 ? -7.50152 -15.06274 -12.62349 1.000 41.76313 ? 199  ALA A N   1 
ATOM   1195 C  CA  . ALA A  1 168 ? -8.24272 -13.99512 -13.28659 1.000 42.70490 ? 199  ALA A CA  1 
ATOM   1196 C  C   . ALA A  1 168 ? -7.92998 -13.88959 -14.77466 1.000 47.59896 ? 199  ALA A C   1 
ATOM   1197 O  O   . ALA A  1 168 ? -8.55163 -13.06929 -15.45944 1.000 48.54411 ? 199  ALA A O   1 
ATOM   1198 C  CB  . ALA A  1 168 ? -7.96322 -12.65443 -12.60404 1.000 43.22671 ? 199  ALA A CB  1 
ATOM   1199 N  N   . GLY A  1 169 ? -6.99384 -14.68521 -15.28828 1.000 46.45939 ? 200  GLY A N   1 
ATOM   1200 C  CA  . GLY A  1 169 ? -6.65858 -14.64238 -16.69660 1.000 48.86960 ? 200  GLY A CA  1 
ATOM   1201 C  C   . GLY A  1 169 ? -5.78398 -13.48601 -17.11732 1.000 52.82981 ? 200  GLY A C   1 
ATOM   1202 O  O   . GLY A  1 169 ? -5.77335 -13.13417 -18.30063 1.000 52.43588 ? 200  GLY A O   1 
ATOM   1203 N  N   . ASN A  1 170 ? -5.05379 -12.88376 -16.18665 1.000 47.12636 ? 201  ASN A N   1 
ATOM   1204 C  CA  . ASN A  1 170 ? -4.19678 -11.74328 -16.48697 1.000 47.68428 ? 201  ASN A CA  1 
ATOM   1205 C  C   . ASN A  1 170 ? -3.15580 -12.13599 -17.52885 1.000 48.93469 ? 201  ASN A C   1 
ATOM   1206 O  O   . ASN A  1 170 ? -2.41288 -13.10791 -17.31526 1.000 47.95374 ? 201  ASN A O   1 
ATOM   1207 C  CB  . ASN A  1 170 ? -3.51834 -11.25840 -15.20316 1.000 48.35378 ? 201  ASN A CB  1 
ATOM   1208 C  CG  . ASN A  1 170 ? -2.92706 -9.86392  -15.33709 1.000 48.35688 ? 201  ASN A CG  1 
ATOM   1209 O  OD1 . ASN A  1 170 ? -2.48133 -9.46108  -16.41031 1.000 49.50519 ? 201  ASN A OD1 1 
ATOM   1210 N  ND2 . ASN A  1 170 ? -2.91638 -9.12120  -14.23307 1.000 45.58409 ? 201  ASN A ND2 1 
ATOM   1211 N  N   . PRO A  1 171 ? -3.06581 -11.43003 -18.65980 1.000 52.28946 ? 202  PRO A N   1 
ATOM   1212 C  CA  . PRO A  1 171 ? -2.03121 -11.75063 -19.64713 1.000 54.84528 ? 202  PRO A CA  1 
ATOM   1213 C  C   . PRO A  1 171 ? -0.74382 -10.95582 -19.48757 1.000 51.15628 ? 202  PRO A C   1 
ATOM   1214 O  O   . PRO A  1 171 ? 0.22199  -11.22505 -20.21640 1.000 56.31441 ? 202  PRO A O   1 
ATOM   1215 C  CB  . PRO A  1 171 ? -2.72310 -11.41549 -20.97660 1.000 50.98721 ? 202  PRO A CB  1 
ATOM   1216 C  CG  . PRO A  1 171 ? -3.73964 -10.35063 -20.62475 1.000 52.61697 ? 202  PRO A CG  1 
ATOM   1217 C  CD  . PRO A  1 171 ? -3.91202 -10.31484 -19.11692 1.000 52.74225 ? 202  PRO A CD  1 
ATOM   1218 N  N   . ASN A  1 172 ? -0.70335 -9.99754  -18.56519 1.000 49.27033 ? 203  ASN A N   1 
ATOM   1219 C  CA  . ASN A  1 172 ? 0.46178  -9.15546  -18.32611 1.000 47.60485 ? 203  ASN A CA  1 
ATOM   1220 C  C   . ASN A  1 172 ? 1.01065  -9.36253  -16.91990 1.000 40.48310 ? 203  ASN A C   1 
ATOM   1221 O  O   . ASN A  1 172 ? 1.33269  -8.40280  -16.21845 1.000 40.33490 ? 203  ASN A O   1 
ATOM   1222 C  CB  . ASN A  1 172 ? 0.12194  -7.68162  -18.53807 1.000 50.44206 ? 203  ASN A CB  1 
ATOM   1223 C  CG  . ASN A  1 172 ? -0.68938 -7.44203  -19.79466 1.000 57.54167 ? 203  ASN A CG  1 
ATOM   1224 O  OD1 . ASN A  1 172 ? -0.35999 -7.94697  -20.86984 1.000 57.89923 ? 203  ASN A OD1 1 
ATOM   1225 N  ND2 . ASN A  1 172 ? -1.76392 -6.67066  -19.66362 1.000 55.97489 ? 203  ASN A ND2 1 
ATOM   1226 N  N   . ILE A  1 173 ? 1.10909  -10.61673 -16.47536 1.000 40.43861 ? 204  ILE A N   1 
ATOM   1227 C  CA  . ILE A  1 173 ? 1.67860  -10.88319 -15.15974 1.000 33.13810 ? 204  ILE A CA  1 
ATOM   1228 C  C   . ILE A  1 173 ? 3.16874  -10.57106 -15.19282 1.000 32.34107 ? 204  ILE A C   1 
ATOM   1229 O  O   . ILE A  1 173 ? 3.90668  -11.08212 -16.04565 1.000 33.31670 ? 204  ILE A O   1 
ATOM   1230 C  CB  . ILE A  1 173 ? 1.42048  -12.33583 -14.73466 1.000 34.92118 ? 204  ILE A CB  1 
ATOM   1231 C  CG1 . ILE A  1 173 ? -0.08428 -12.63012 -14.70226 1.000 35.74438 ? 204  ILE A CG1 1 
ATOM   1232 C  CG2 . ILE A  1 173 ? 2.04321  -12.60619 -13.36930 1.000 33.30409 ? 204  ILE A CG2 1 
ATOM   1233 C  CD1 . ILE A  1 173 ? -0.42177 -14.04515 -14.26017 1.000 33.88538 ? 204  ILE A CD1 1 
ATOM   1234 N  N   . ARG A  1 174 ? 3.61187  -9.72073  -14.26892 1.000 31.96103 ? 205  ARG A N   1 
ATOM   1235 C  CA  . ARG A  1 174 ? 5.00834  -9.29789  -14.22308 1.000 31.13878 ? 205  ARG A CA  1 
ATOM   1236 C  C   . ARG A  1 174 ? 5.90584  -10.43183 -13.74231 1.000 30.35971 ? 205  ARG A C   1 
ATOM   1237 O  O   . ARG A  1 174 ? 5.55326  -11.17130 -12.81617 1.000 25.98517 ? 205  ARG A O   1 
ATOM   1238 C  CB  . ARG A  1 174 ? 5.15271  -8.09900  -13.29032 1.000 30.45214 ? 205  ARG A CB  1 
ATOM   1239 C  CG  . ARG A  1 174 ? 4.66312  -6.78973  -13.87791 1.000 43.55157 ? 205  ARG A CG  1 
ATOM   1240 C  CD  . ARG A  1 174 ? 5.76293  -6.17422  -14.72938 1.000 49.69372 ? 205  ARG A CD  1 
ATOM   1241 N  NE  . ARG A  1 174 ? 5.42055  -4.87129  -15.28116 1.000 54.54596 ? 205  ARG A NE  1 
ATOM   1242 C  CZ  . ARG A  1 174 ? 6.25957  -3.84701  -15.32317 1.000 52.75264 ? 205  ARG A CZ  1 
ATOM   1243 N  NH1 . ARG A  1 174 ? 7.47491  -3.92757  -14.80249 1.000 52.03778 ? 205  ARG A NH1 1 
ATOM   1244 N  NH2 . ARG A  1 174 ? 5.86717  -2.71065  -15.89176 1.000 58.42819 ? 205  ARG A NH2 1 
ATOM   1245 N  N   . ASP A  1 175 ? 7.09259  -10.55593 -14.34937 1.000 25.72097 ? 206  ASP A N   1 
ATOM   1246 C  CA  . ASP A  1 175 ? 7.93672  -11.67562 -13.95095 1.000 24.86654 ? 206  ASP A CA  1 
ATOM   1247 C  C   . ASP A  1 175 ? 8.46980  -11.53003 -12.52789 1.000 23.33282 ? 206  ASP A C   1 
ATOM   1248 O  O   . ASP A  1 175 ? 8.96227  -12.52023 -11.97711 1.000 22.74593 ? 206  ASP A O   1 
ATOM   1249 C  CB  . ASP A  1 175 ? 9.07572  -11.91160 -14.97181 1.000 22.52178 ? 206  ASP A CB  1 
ATOM   1250 C  CG  . ASP A  1 175 ? 9.96598  -10.69364 -15.20369 1.000 25.97805 ? 206  ASP A CG  1 
ATOM   1251 O  OD1 . ASP A  1 175 ? 9.92968  -9.73671  -14.40151 1.000 27.75913 ? 206  ASP A OD1 1 
ATOM   1252 O  OD2 . ASP A  1 175 ? 10.73055 -10.71392 -16.20770 1.000 25.67316 ? 206  ASP A OD2 1 
ATOM   1253 N  N   . TYR A  1 176 ? 8.30457  -10.36177 -11.89170 1.000 22.81124 ? 207  TYR A N   1 
ATOM   1254 C  CA  . TYR A  1 176 ? 8.71268  -10.20921 -10.49425 1.000 21.00861 ? 207  TYR A CA  1 
ATOM   1255 C  C   . TYR A  1 176 ? 7.87680  -11.05166 -9.53245  1.000 23.41963 ? 207  TYR A C   1 
ATOM   1256 O  O   . TYR A  1 176 ? 8.28681  -11.23883 -8.37944  1.000 21.74863 ? 207  TYR A O   1 
ATOM   1257 C  CB  . TYR A  1 176 ? 8.63486  -8.74320  -10.05428 1.000 22.75262 ? 207  TYR A CB  1 
ATOM   1258 C  CG  . TYR A  1 176 ? 9.90152  -7.93550  -10.28278 1.000 22.62409 ? 207  TYR A CG  1 
ATOM   1259 C  CD1 . TYR A  1 176 ? 10.53633 -7.93790  -11.51697 1.000 22.38681 ? 207  TYR A CD1 1 
ATOM   1260 C  CD2 . TYR A  1 176 ? 10.44009 -7.14604  -9.26694  1.000 24.10577 ? 207  TYR A CD2 1 
ATOM   1261 C  CE1 . TYR A  1 176 ? 11.69747 -7.18203  -11.73209 1.000 22.53082 ? 207  TYR A CE1 1 
ATOM   1262 C  CE2 . TYR A  1 176 ? 11.59293 -6.38564  -9.47236  1.000 23.38315 ? 207  TYR A CE2 1 
ATOM   1263 C  CZ  . TYR A  1 176 ? 12.20854 -6.40895  -10.70643 1.000 22.83123 ? 207  TYR A CZ  1 
ATOM   1264 O  OH  . TYR A  1 176 ? 13.34256 -5.65848  -10.92089 1.000 22.10167 ? 207  TYR A OH  1 
ATOM   1265 N  N   . VAL A  1 177 ? 6.71520  -11.55292 -9.95442  1.000 21.89455 ? 208  VAL A N   1 
ATOM   1266 C  CA  . VAL A  1 177 ? 5.90289  -12.39834 -9.08194  1.000 22.51459 ? 208  VAL A CA  1 
ATOM   1267 C  C   . VAL A  1 177 ? 5.81690  -13.83594 -9.59009  1.000 24.47979 ? 208  VAL A C   1 
ATOM   1268 O  O   . VAL A  1 177 ? 5.09527  -14.64901 -9.00023  1.000 26.16255 ? 208  VAL A O   1 
ATOM   1269 C  CB  . VAL A  1 177 ? 4.49444  -11.81366 -8.85851  1.000 22.29897 ? 208  VAL A CB  1 
ATOM   1270 C  CG1 . VAL A  1 177 ? 4.57234  -10.46958 -8.14205  1.000 25.14648 ? 208  VAL A CG1 1 
ATOM   1271 C  CG2 . VAL A  1 177 ? 3.72942  -11.71763 -10.17160 1.000 27.52129 ? 208  VAL A CG2 1 
ATOM   1272 N  N   . PHE A  1 178 ? 6.53981  -14.17839 -10.65569 1.000 23.08741 ? 209  PHE A N   1 
ATOM   1273 C  CA  . PHE A  1 178 ? 6.54904  -15.55907 -11.13219 1.000 25.40554 ? 209  PHE A CA  1 
ATOM   1274 C  C   . PHE A  1 178 ? 7.10763  -16.48590 -10.05452 1.000 23.94156 ? 209  PHE A C   1 
ATOM   1275 O  O   . PHE A  1 178 ? 8.05285  -16.11748 -9.34416  1.000 22.15342 ? 209  PHE A O   1 
ATOM   1276 C  CB  . PHE A  1 178 ? 7.41517  -15.71928 -12.38593 1.000 26.44482 ? 209  PHE A CB  1 
ATOM   1277 C  CG  . PHE A  1 178 ? 6.81454  -15.16969 -13.65290 1.000 29.30836 ? 209  PHE A CG  1 
ATOM   1278 C  CD1 . PHE A  1 178 ? 5.54867  -14.60514 -13.67899 1.000 29.63556 ? 209  PHE A CD1 1 
ATOM   1279 C  CD2 . PHE A  1 178 ? 7.53470  -15.24309 -14.83822 1.000 27.77279 ? 209  PHE A CD2 1 
ATOM   1280 C  CE1 . PHE A  1 178 ? 5.01682  -14.11212 -14.86747 1.000 29.18711 ? 209  PHE A CE1 1 
ATOM   1281 C  CE2 . PHE A  1 178 ? 7.00734  -14.75441 -16.03003 1.000 30.35254 ? 209  PHE A CE2 1 
ATOM   1282 C  CZ  . PHE A  1 178 ? 5.74585  -14.19098 -16.04221 1.000 29.94518 ? 209  PHE A CZ  1 
ATOM   1283 N  N   . PRO A  1 179 ? 6.58252  -17.70218 -9.92355  1.000 24.39948 ? 210  PRO A N   1 
ATOM   1284 C  CA  . PRO A  1 179 ? 7.25517  -18.69285 -9.07783  1.000 22.92124 ? 210  PRO A CA  1 
ATOM   1285 C  C   . PRO A  1 179 ? 8.70497  -18.86344 -9.50619  1.000 22.24042 ? 210  PRO A C   1 
ATOM   1286 O  O   . PRO A  1 179 ? 9.03142  -18.86168 -10.69568 1.000 24.62129 ? 210  PRO A O   1 
ATOM   1287 C  CB  . PRO A  1 179 ? 6.44123  -19.97835 -9.30083  1.000 26.94097 ? 210  PRO A CB  1 
ATOM   1288 C  CG  . PRO A  1 179 ? 5.55429  -19.70371 -10.48587 1.000 32.62917 ? 210  PRO A CG  1 
ATOM   1289 C  CD  . PRO A  1 179 ? 5.33961  -18.22223 -10.51678 1.000 28.59591 ? 210  PRO A CD  1 
ATOM   1290 N  N   . MET A  1 180 ? 9.58583  -18.96066 -8.51954  1.000 22.93969 ? 211  MET A N   1 
ATOM   1291 C  CA  . MET A  1 180 ? 10.96532 -19.31650 -8.78921  1.000 20.38170 ? 211  MET A CA  1 
ATOM   1292 C  C   . MET A  1 180 ? 11.04566 -20.78571 -9.18071  1.000 25.24013 ? 211  MET A C   1 
ATOM   1293 O  O   . MET A  1 180 ? 10.06592 -21.53250 -9.09787  1.000 24.54796 ? 211  MET A O   1 
ATOM   1294 C  CB  . MET A  1 180 ? 11.82803 -19.01854 -7.56759  1.000 20.45966 ? 211  MET A CB  1 
ATOM   1295 C  CG  . MET A  1 180 ? 11.74316 -17.54644 -7.18788  1.000 23.26775 ? 211  MET A CG  1 
ATOM   1296 S  SD  . MET A  1 180 ? 13.12183 -17.00153 -6.15968  1.000 22.81892 ? 211  MET A SD  1 
ATOM   1297 C  CE  . MET A  1 180 ? 12.80930 -17.93988 -4.66135  1.000 22.47163 ? 211  MET A CE  1 
ATOM   1298 N  N   . GLU A  1 181 ? 12.22414 -21.20848 -9.62249  1.000 21.07878 ? 212  GLU A N   1 
ATOM   1299 C  CA  . GLU A  1 181 ? 12.38008 -22.57673 -10.08742 1.000 22.71257 ? 212  GLU A CA  1 
ATOM   1300 C  C   . GLU A  1 181 ? 13.58402 -23.24182 -9.44064  1.000 24.69733 ? 212  GLU A C   1 
ATOM   1301 O  O   . GLU A  1 181 ? 14.51623 -22.59101 -8.95560  1.000 23.13969 ? 212  GLU A O   1 
ATOM   1302 C  CB  . GLU A  1 181 ? 12.52572 -22.65944 -11.60916 1.000 23.06620 ? 212  GLU A CB  1 
ATOM   1303 C  CG  . GLU A  1 181 ? 13.70000 -21.86874 -12.16992 1.000 23.85972 ? 212  GLU A CG  1 
ATOM   1304 C  CD  . GLU A  1 181 ? 14.04571 -22.31687 -13.57662 1.000 21.76481 ? 212  GLU A CD  1 
ATOM   1305 O  OE1 . GLU A  1 181 ? 14.74269 -23.34171 -13.72221 1.000 23.91013 ? 212  GLU A OE1 1 
ATOM   1306 O  OE2 . GLU A  1 181 ? 13.57754 -21.67615 -14.53848 1.000 25.47733 ? 212  GLU A OE2 1 
ATOM   1307 N  N   . HIS A  1 182 ? 13.53631 -24.56884 -9.44604  1.000 21.87195 ? 213  HIS A N   1 
ATOM   1308 C  CA  . HIS A  1 182 ? 14.67456 -25.41200 -9.11975  1.000 20.77737 ? 213  HIS A CA  1 
ATOM   1309 C  C   . HIS A  1 182 ? 14.84791 -26.36817 -10.28930 1.000 27.53439 ? 213  HIS A C   1 
ATOM   1310 O  O   . HIS A  1 182 ? 14.02077 -27.26797 -10.47618 1.000 24.93852 ? 213  HIS A O   1 
ATOM   1311 C  CB  . HIS A  1 182 ? 14.44859 -26.17597 -7.81667  1.000 24.74605 ? 213  HIS A CB  1 
ATOM   1312 C  CG  . HIS A  1 182 ? 15.62111 -27.00144 -7.39798  1.000 26.69106 ? 213  HIS A CG  1 
ATOM   1313 N  ND1 . HIS A  1 182 ? 15.49171 -28.16744 -6.67277  1.000 36.41750 ? 213  HIS A ND1 1 
ATOM   1314 C  CD2 . HIS A  1 182 ? 16.94936 -26.83394 -7.60988  1.000 25.40493 ? 213  HIS A CD2 1 
ATOM   1315 C  CE1 . HIS A  1 182 ? 16.69025 -28.68100 -6.45224  1.000 33.93622 ? 213  HIS A CE1 1 
ATOM   1316 N  NE2 . HIS A  1 182 ? 17.59277 -27.88758 -7.00368  1.000 30.14258 ? 213  HIS A NE2 1 
ATOM   1317 N  N   . ASN A  1 183 ? 15.90280 -26.15876 -11.08407 1.000 23.34168 ? 214  ASN A N   1 
ATOM   1318 C  CA  . ASN A  1 183 ? 16.20042 -26.99862 -12.24577 1.000 23.13105 ? 214  ASN A CA  1 
ATOM   1319 C  C   . ASN A  1 183 ? 14.95983 -27.19125 -13.11284 1.000 27.45076 ? 214  ASN A C   1 
ATOM   1320 O  O   . ASN A  1 183 ? 14.61848 -28.30426 -13.51677 1.000 29.36888 ? 214  ASN A O   1 
ATOM   1321 C  CB  . ASN A  1 183 ? 16.78027 -28.34773 -11.81431 1.000 26.41101 ? 214  ASN A CB  1 
ATOM   1322 C  CG  . ASN A  1 183 ? 18.10288 -28.20372 -11.09139 1.000 28.77210 ? 214  ASN A CG  1 
ATOM   1323 O  OD1 . ASN A  1 183 ? 18.88706 -27.29230 -11.38314 1.000 24.06521 ? 214  ASN A OD1 1 
ATOM   1324 N  ND2 . ASN A  1 183 ? 18.36164 -29.09684 -10.14183 1.000 29.66697 ? 214  ASN A ND2 1 
ATOM   1325 N  N   . GLY A  1 184 ? 14.26473 -26.08930 -13.37433 1.000 28.36218 ? 215  GLY A N   1 
ATOM   1326 C  CA  . GLY A  1 184 ? 13.09845 -26.10808 -14.23520 1.000 27.39736 ? 215  GLY A CA  1 
ATOM   1327 C  C   . GLY A  1 184 ? 11.80552 -26.54232 -13.58123 1.000 32.43377 ? 215  GLY A C   1 
ATOM   1328 O  O   . GLY A  1 184 ? 10.76596 -26.53808 -14.25158 1.000 34.88265 ? 215  GLY A O   1 
ATOM   1329 N  N   . LYS A  1 185 ? 11.82620 -26.91302 -12.30704 1.000 26.72942 ? 216  LYS A N   1 
ATOM   1330 C  CA  . LYS A  1 185 ? 10.63934 -27.29797 -11.55637 1.000 31.83167 ? 216  LYS A CA  1 
ATOM   1331 C  C   . LYS A  1 185 ? 10.26147 -26.20425 -10.55927 1.000 31.47299 ? 216  LYS A C   1 
ATOM   1332 O  O   . LYS A  1 185 ? 11.09834 -25.36764 -10.20264 1.000 25.06817 ? 216  LYS A O   1 
ATOM   1333 C  CB  . LYS A  1 185 ? 10.88625 -28.61994 -10.81141 1.000 32.89127 ? 216  LYS A CB  1 
ATOM   1334 C  CG  . LYS A  1 185 ? 10.68960 -29.87296 -11.65872 1.000 40.91177 ? 216  LYS A CG  1 
ATOM   1335 C  CD  . LYS A  1 185 ? 11.72352 -30.00581 -12.76277 1.000 40.67106 ? 216  LYS A CD  1 
ATOM   1336 C  CE  . LYS A  1 185 ? 11.46462 -31.23994 -13.62661 1.000 50.42150 ? 216  LYS A CE  1 
ATOM   1337 N  NZ  . LYS A  1 185 ? 12.41347 -31.32123 -14.77693 1.000 57.05257 ? 216  LYS A NZ  1 
ATOM   1338 N  N   . PRO A  1 186 ? 9.01332  -26.17842 -10.08012 1.000 28.90454 ? 217  PRO A N   1 
ATOM   1339 C  CA  . PRO A  1 186 ? 8.62129  -25.13528 -9.11947  1.000 30.02762 ? 217  PRO A CA  1 
ATOM   1340 C  C   . PRO A  1 186 ? 9.47322  -25.19248 -7.85951  1.000 33.07192 ? 217  PRO A C   1 
ATOM   1341 O  O   . PRO A  1 186 ? 9.74187  -26.26684 -7.31248  1.000 31.91491 ? 217  PRO A O   1 
ATOM   1342 C  CB  . PRO A  1 186 ? 7.15076  -25.45848 -8.82042  1.000 35.55324 ? 217  PRO A CB  1 
ATOM   1343 C  CG  . PRO A  1 186 ? 6.68452  -26.23425 -10.01864 1.000 32.01732 ? 217  PRO A CG  1 
ATOM   1344 C  CD  . PRO A  1 186 ? 7.87367  -27.05003 -10.43654 1.000 29.61637 ? 217  PRO A CD  1 
ATOM   1345 N  N   . ALA A  1 187 ? 9.91299  -24.01471 -7.40856  1.000 25.97346 ? 218  ALA A N   1 
ATOM   1346 C  CA  . ALA A  1 187 ? 10.77369 -23.94825 -6.23416  1.000 25.56194 ? 218  ALA A CA  1 
ATOM   1347 C  C   . ALA A  1 187 ? 9.99254  -24.10214 -4.93570  1.000 23.89990 ? 218  ALA A C   1 
ATOM   1348 O  O   . ALA A  1 187 ? 10.53372 -24.62710 -3.95472  1.000 27.76629 ? 218  ALA A O   1 
ATOM   1349 C  CB  . ALA A  1 187 ? 11.54865 -22.62794 -6.22312  1.000 26.09334 ? 218  ALA A CB  1 
ATOM   1350 N  N   . ASN A  1 188 ? 8.73873  -23.64571 -4.90566  1.000 26.40012 ? 219  ASN A N   1 
ATOM   1351 C  CA  . ASN A  1 188 ? 7.90784  -23.67448 -3.69962  1.000 29.16917 ? 219  ASN A CA  1 
ATOM   1352 C  C   . ASN A  1 188 ? 8.61405  -23.01547 -2.51512  1.000 29.60331 ? 219  ASN A C   1 
ATOM   1353 O  O   . ASN A  1 188 ? 8.64500  -23.54119 -1.39801  1.000 26.45281 ? 219  ASN A O   1 
ATOM   1354 C  CB  . ASN A  1 188 ? 7.49199  -25.10862 -3.36401  1.000 34.00180 ? 219  ASN A CB  1 
ATOM   1355 C  CG  . ASN A  1 188 ? 6.66543  -25.74239 -4.46626  1.000 36.88034 ? 219  ASN A CG  1 
ATOM   1356 O  OD1 . ASN A  1 188 ? 5.74896  -25.12097 -5.00283  1.000 40.65464 ? 219  ASN A OD1 1 
ATOM   1357 N  ND2 . ASN A  1 188 ? 6.99653  -26.97734 -4.81964  1.000 39.25404 ? 219  ASN A ND2 1 
ATOM   1358 N  N   . GLU A  1 189 ? 9.19468  -21.84527 -2.77199  1.000 25.57031 ? 220  GLU A N   1 
ATOM   1359 C  CA  . GLU A  1 189 ? 9.89659  -21.12211 -1.72286  1.000 22.83130 ? 220  GLU A CA  1 
ATOM   1360 C  C   . GLU A  1 189 ? 8.93839  -20.74732 -0.59624  1.000 24.33400 ? 220  GLU A C   1 
ATOM   1361 O  O   . GLU A  1 189 ? 7.78073  -20.39463 -0.83200  1.000 27.44273 ? 220  GLU A O   1 
ATOM   1362 C  CB  . GLU A  1 189 ? 10.55007 -19.86502 -2.30751  1.000 22.54732 ? 220  GLU A CB  1 
ATOM   1363 C  CG  . GLU A  1 189 ? 11.34143 -19.04772 -1.30625  1.000 23.19438 ? 220  GLU A CG  1 
ATOM   1364 C  CD  . GLU A  1 189 ? 12.45787 -19.83919 -0.67193  1.000 24.07693 ? 220  GLU A CD  1 
ATOM   1365 O  OE1 . GLU A  1 189 ? 13.41876 -20.19573 -1.39071  1.000 24.29555 ? 220  GLU A OE1 1 
ATOM   1366 O  OE2 . GLU A  1 189 ? 12.36836 -20.11817 0.54045   1.000 23.45667 ? 220  GLU A OE2 1 
ATOM   1367 N  N   . THR A  1 190 ? 9.42825  -20.82443 0.63999   1.000 22.44028 ? 221  THR A N   1 
ATOM   1368 C  CA  . THR A  1 190 ? 8.63697  -20.44714 1.79830   1.000 22.40521 ? 221  THR A CA  1 
ATOM   1369 C  C   . THR A  1 190 ? 9.26250  -19.35252 2.64667   1.000 25.23811 ? 221  THR A C   1 
ATOM   1370 O  O   . THR A  1 190 ? 8.60668  -18.87517 3.57688   1.000 27.63233 ? 221  THR A O   1 
ATOM   1371 C  CB  . THR A  1 190 ? 8.38430  -21.66864 2.69010   1.000 28.18207 ? 221  THR A CB  1 
ATOM   1372 O  OG1 . THR A  1 190 ? 9.64094  -22.18562 3.13341   1.000 29.63771 ? 221  THR A OG1 1 
ATOM   1373 C  CG2 . THR A  1 190 ? 7.64047  -22.74436 1.90457   1.000 31.98779 ? 221  THR A CG2 1 
ATOM   1374 N  N   . GLU A  1 191 ? 10.49503 -18.93942 2.36159   1.000 21.70303 ? 222  GLU A N   1 
ATOM   1375 C  CA  . GLU A  1 191 ? 11.19667 -17.94280 3.15320   1.000 21.45640 ? 222  GLU A CA  1 
ATOM   1376 C  C   . GLU A  1 191 ? 11.39696 -16.67496 2.33450   1.000 19.70485 ? 222  GLU A C   1 
ATOM   1377 O  O   . GLU A  1 191 ? 11.39024 -16.70525 1.10026   1.000 22.32939 ? 222  GLU A O   1 
ATOM   1378 C  CB  . GLU A  1 191 ? 12.56781 -18.45903 3.61090   1.000 21.75268 ? 222  GLU A CB  1 
ATOM   1379 C  CG  . GLU A  1 191 ? 12.55229 -19.82643 4.26578   1.000 23.78290 ? 222  GLU A CG  1 
ATOM   1380 C  CD  . GLU A  1 191 ? 13.88938 -20.16236 4.92327   1.000 25.77787 ? 222  GLU A CD  1 
ATOM   1381 O  OE1 . GLU A  1 191 ? 14.36936 -19.35509 5.75134   1.000 27.59245 ? 222  GLU A OE1 1 
ATOM   1382 O  OE2 . GLU A  1 191 ? 14.46376 -21.22946 4.60931   1.000 28.35677 ? 222  GLU A OE2 1 
ATOM   1383 N  N   . TYR A  1 192 ? 11.54905 -15.55538 3.04222   1.000 20.00761 ? 223  TYR A N   1 
ATOM   1384 C  CA  . TYR A  1 192 ? 12.14047 -14.35199 2.46331   1.000 17.63430 ? 223  TYR A CA  1 
ATOM   1385 C  C   . TYR A  1 192 ? 13.28224 -14.76395 1.53972   1.000 19.08900 ? 223  TYR A C   1 
ATOM   1386 O  O   . TYR A  1 192 ? 14.15106 -15.54534 1.93291   1.000 20.11735 ? 223  TYR A O   1 
ATOM   1387 C  CB  . TYR A  1 192 ? 12.64863 -13.47185 3.60584   1.000 20.24850 ? 223  TYR A CB  1 
ATOM   1388 C  CG  . TYR A  1 192 ? 13.28420 -12.15893 3.23035   1.000 18.22306 ? 223  TYR A CG  1 
ATOM   1389 C  CD1 . TYR A  1 192 ? 12.51551 -11.11350 2.73305   1.000 19.22688 ? 223  TYR A CD1 1 
ATOM   1390 C  CD2 . TYR A  1 192 ? 14.64457 -11.94061 3.42760   1.000 19.90353 ? 223  TYR A CD2 1 
ATOM   1391 C  CE1 . TYR A  1 192 ? 13.08511 -9.87922  2.42376   1.000 19.08462 ? 223  TYR A CE1 1 
ATOM   1392 C  CE2 . TYR A  1 192 ? 15.22825 -10.71009 3.11894   1.000 18.15352 ? 223  TYR A CE2 1 
ATOM   1393 C  CZ  . TYR A  1 192 ? 14.44177 -9.68587  2.61136   1.000 16.84902 ? 223  TYR A CZ  1 
ATOM   1394 O  OH  . TYR A  1 192 ? 15.00234 -8.46201  2.29821   1.000 17.55257 ? 223  TYR A OH  1 
ATOM   1395 N  N   . ILE A  1 193 ? 13.24442 -14.31355 0.27997   1.000 19.33366 ? 224  ILE A N   1 
ATOM   1396 C  CA  . ILE A  1 193 ? 14.01599 -15.08220 -0.69506  1.000 17.03472 ? 224  ILE A CA  1 
ATOM   1397 C  C   . ILE A  1 193 ? 15.52200 -14.95619 -0.47635  1.000 17.78216 ? 224  ILE A C   1 
ATOM   1398 O  O   . ILE A  1 193 ? 16.25899 -15.87891 -0.84504  1.000 18.19323 ? 224  ILE A O   1 
ATOM   1399 C  CB  . ILE A  1 193 ? 13.65129 -14.75449 -2.15743  1.000 17.68568 ? 224  ILE A CB  1 
ATOM   1400 C  CG1 . ILE A  1 193 ? 14.03251 -13.33082 -2.56034  1.000 18.95246 ? 224  ILE A CG1 1 
ATOM   1401 C  CG2 . ILE A  1 193 ? 12.17186 -15.06736 -2.44078  1.000 21.77101 ? 224  ILE A CG2 1 
ATOM   1402 C  CD1 . ILE A  1 193 ? 13.73021 -13.08099 -4.04920  1.000 19.38766 ? 224  ILE A CD1 1 
ATOM   1403 N  N   . THR A  1 194 ? 16.00099 -13.87224 0.15134   1.000 17.26417 ? 225  THR A N   1 
ATOM   1404 C  CA  . THR A  1 194 ? 17.40987 -13.82231 0.53101   1.000 17.28451 ? 225  THR A CA  1 
ATOM   1405 C  C   . THR A  1 194 ? 17.76048 -14.98413 1.44759   1.000 17.86678 ? 225  THR A C   1 
ATOM   1406 O  O   . THR A  1 194 ? 18.80050 -15.63038 1.27347   1.000 16.85306 ? 225  THR A O   1 
ATOM   1407 C  CB  . THR A  1 194 ? 17.72577 -12.48340 1.20219   1.000 17.56372 ? 225  THR A CB  1 
ATOM   1408 O  OG1 . THR A  1 194 ? 17.39413 -11.42411 0.30303   1.000 17.49738 ? 225  THR A OG1 1 
ATOM   1409 C  CG2 . THR A  1 194 ? 19.20498 -12.36997 1.59041   1.000 16.13894 ? 225  THR A CG2 1 
ATOM   1410 N  N   . ASP A  1 195 ? 16.89606 -15.26955 2.42910   1.000 18.05876 ? 226  ASP A N   1 
ATOM   1411 C  CA  . ASP A  1 195 ? 17.12556 -16.41920 3.29965   1.000 18.52352 ? 226  ASP A CA  1 
ATOM   1412 C  C   . ASP A  1 195 ? 17.05678 -17.73082 2.52397   1.000 20.20528 ? 226  ASP A C   1 
ATOM   1413 O  O   . ASP A  1 195 ? 17.83052 -18.66282 2.79231   1.000 20.24346 ? 226  ASP A O   1 
ATOM   1414 C  CB  . ASP A  1 195 ? 16.10728 -16.43047 4.44135   1.000 19.44863 ? 226  ASP A CB  1 
ATOM   1415 C  CG  . ASP A  1 195 ? 16.29218 -15.27766 5.41515   1.000 21.60085 ? 226  ASP A CG  1 
ATOM   1416 O  OD1 . ASP A  1 195 ? 17.35589 -14.63685 5.41006   1.000 23.42228 ? 226  ASP A OD1 1 
ATOM   1417 O  OD2 . ASP A  1 195 ? 15.35749 -15.02511 6.20940   1.000 25.00114 ? 226  ASP A OD2 1 
ATOM   1418 N  N   . GLY A  1 196 ? 16.13156 -17.82699 1.56606   1.000 17.87962 ? 227  GLY A N   1 
ATOM   1419 C  CA  . GLY A  1 196 ? 16.03778 -19.03461 0.76069   1.000 18.62698 ? 227  GLY A CA  1 
ATOM   1420 C  C   . GLY A  1 196 ? 17.28087 -19.27323 -0.07762  1.000 19.60999 ? 227  GLY A C   1 
ATOM   1421 O  O   . GLY A  1 196 ? 17.76317 -20.40587 -0.18477  1.000 19.03460 ? 227  GLY A O   1 
ATOM   1422 N  N   . PHE A  1 197 ? 17.82830 -18.20398 -0.67089  1.000 19.24271 ? 228  PHE A N   1 
ATOM   1423 C  CA  . PHE A  1 197 ? 19.05240 -18.34124 -1.45052  1.000 16.38325 ? 228  PHE A CA  1 
ATOM   1424 C  C   . PHE A  1 197 ? 20.22128 -18.74677 -0.56298  1.000 17.84397 ? 228  PHE A C   1 
ATOM   1425 O  O   . PHE A  1 197 ? 21.06112 -19.55532 -0.97111  1.000 18.94269 ? 228  PHE A O   1 
ATOM   1426 C  CB  . PHE A  1 197 ? 19.37256 -17.03327 -2.19060  1.000 16.27371 ? 228  PHE A CB  1 
ATOM   1427 C  CG  . PHE A  1 197 ? 18.31675 -16.61804 -3.18652  1.000 17.73238 ? 228  PHE A CG  1 
ATOM   1428 C  CD1 . PHE A  1 197 ? 17.54483 -17.55755 -3.84377  1.000 17.82225 ? 228  PHE A CD1 1 
ATOM   1429 C  CD2 . PHE A  1 197 ? 18.09740 -15.27506 -3.45306  1.000 18.27470 ? 228  PHE A CD2 1 
ATOM   1430 C  CE1 . PHE A  1 197 ? 16.57983 -17.15637 -4.76288  1.000 16.74630 ? 228  PHE A CE1 1 
ATOM   1431 C  CE2 . PHE A  1 197 ? 17.13495 -14.86330 -4.36577  1.000 17.85384 ? 228  PHE A CE2 1 
ATOM   1432 C  CZ  . PHE A  1 197 ? 16.37238 -15.80715 -5.02476  1.000 19.33101 ? 228  PHE A CZ  1 
ATOM   1433 N  N   . SER A  1 198 ? 20.28718 -18.20230 0.65766   1.000 18.03347 ? 229  SER A N   1 
ATOM   1434 C  CA  . SER A  1 198 ? 21.33353 -18.61928 1.58629   1.000 18.49287 ? 229  SER A CA  1 
ATOM   1435 C  C   . SER A  1 198 ? 21.17524 -20.08542 1.95020   1.000 19.56725 ? 229  SER A C   1 
ATOM   1436 O  O   . SER A  1 198 ? 22.16445 -20.82274 2.04194   1.000 18.50456 ? 229  SER A O   1 
ATOM   1437 C  CB  . SER A  1 198 ? 21.28986 -17.75412 2.84756   1.000 18.91569 ? 229  SER A CB  1 
ATOM   1438 O  OG  . SER A  1 198 ? 21.44883 -16.37248 2.53978   1.000 16.70598 ? 229  SER A OG  1 
ATOM   1439 N  N   . ARG A  1 199 ? 19.92760 -20.51859 2.15622   1.000 18.29588 ? 230  ARG A N   1 
ATOM   1440 C  CA  . ARG A  1 199 ? 19.63685 -21.91332 2.47223   1.000 19.71856 ? 230  ARG A CA  1 
ATOM   1441 C  C   . ARG A  1 199 ? 20.11891 -22.83249 1.36258   1.000 19.93592 ? 230  ARG A C   1 
ATOM   1442 O  O   . ARG A  1 199 ? 20.74293 -23.86958 1.62210   1.000 20.27912 ? 230  ARG A O   1 
ATOM   1443 C  CB  . ARG A  1 199 ? 18.13003 -22.08522 2.68931   1.000 19.87257 ? 230  ARG A CB  1 
ATOM   1444 C  CG  . ARG A  1 199 ? 17.69438 -23.50432 3.04314   1.000 22.65007 ? 230  ARG A CG  1 
ATOM   1445 C  CD  . ARG A  1 199 ? 16.20120 -23.70823 2.79689   1.000 21.44945 ? 230  ARG A CD  1 
ATOM   1446 N  NE  . ARG A  1 199 ? 15.82949 -23.53729 1.39686   1.000 23.16883 ? 230  ARG A NE  1 
ATOM   1447 C  CZ  . ARG A  1 199 ? 14.95294 -22.64495 0.95677   1.000 20.36267 ? 230  ARG A CZ  1 
ATOM   1448 N  NH1 . ARG A  1 199 ? 14.29547 -21.85260 1.78727   1.000 21.16983 ? 230  ARG A NH1 1 
ATOM   1449 N  NH2 . ARG A  1 199 ? 14.72546 -22.54817 -0.35178  1.000 22.84037 ? 230  ARG A NH2 1 
ATOM   1450 N  N   . GLU A  1 200 ? 19.83653 -22.46502 0.11165   1.000 18.17157 ? 231  GLU A N   1 
ATOM   1451 C  CA  . GLU A  1 200 ? 20.25882 -23.29412 -1.00877  1.000 18.31355 ? 231  GLU A CA  1 
ATOM   1452 C  C   . GLU A  1 200 ? 21.77517 -23.29128 -1.17358  1.000 19.24735 ? 231  GLU A C   1 
ATOM   1453 O  O   . GLU A  1 200 ? 22.34999 -24.30131 -1.58409  1.000 18.63283 ? 231  GLU A O   1 
ATOM   1454 C  CB  . GLU A  1 200 ? 19.56838 -22.82561 -2.28966  1.000 18.98618 ? 231  GLU A CB  1 
ATOM   1455 C  CG  . GLU A  1 200 ? 18.04775 -22.97624 -2.25629  1.000 22.65721 ? 231  GLU A CG  1 
ATOM   1456 C  CD  . GLU A  1 200 ? 17.60875 -24.42518 -2.04763  1.000 24.80586 ? 231  GLU A CD  1 
ATOM   1457 O  OE1 . GLU A  1 200 ? 18.16314 -25.33321 -2.72311  1.000 23.90249 ? 231  GLU A OE1 1 
ATOM   1458 O  OE2 . GLU A  1 200 ? 16.72417 -24.65828 -1.19534  1.000 26.51041 ? 231  GLU A OE2 1 
ATOM   1459 N  N   . ALA A  1 201 ? 22.44541 -22.17948 -0.86471  1.000 17.98797 ? 232  ALA A N   1 
ATOM   1460 C  CA  . ALA A  1 201 ? 23.90378 -22.18774 -0.92171  1.000 18.27930 ? 232  ALA A CA  1 
ATOM   1461 C  C   . ALA A  1 201 ? 24.47786 -23.17443 0.08880   1.000 18.50370 ? 232  ALA A C   1 
ATOM   1462 O  O   . ALA A  1 201 ? 25.40859 -23.93443 -0.22145  1.000 19.67250 ? 232  ALA A O   1 
ATOM   1463 C  CB  . ALA A  1 201 ? 24.45043 -20.77976 -0.67221  1.000 18.87566 ? 232  ALA A CB  1 
ATOM   1464 N  N   . ILE A  1 202 ? 23.92308 -23.17350 1.30010   1.000 19.87448 ? 233  ILE A N   1 
ATOM   1465 C  CA  . ILE A  1 202 ? 24.32672 -24.11681 2.33839   1.000 19.88179 ? 233  ILE A CA  1 
ATOM   1466 C  C   . ILE A  1 202 ? 24.13624 -25.54580 1.85681   1.000 19.07846 ? 233  ILE A C   1 
ATOM   1467 O  O   . ILE A  1 202 ? 25.01662 -26.40513 2.02602   1.000 20.62877 ? 233  ILE A O   1 
ATOM   1468 C  CB  . ILE A  1 202 ? 23.52182 -23.83293 3.62059   1.000 20.32708 ? 233  ILE A CB  1 
ATOM   1469 C  CG1 . ILE A  1 202 ? 23.92956 -22.48787 4.21734   1.000 22.63236 ? 233  ILE A CG1 1 
ATOM   1470 C  CG2 . ILE A  1 202 ? 23.68553 -24.96019 4.64358   1.000 21.08222 ? 233  ILE A CG2 1 
ATOM   1471 C  CD1 . ILE A  1 202 ? 22.99116 -22.00249 5.31962   1.000 21.23426 ? 233  ILE A CD1 1 
ATOM   1472 N  N   . LYS A  1 203 ? 22.99243 -25.81367 1.23551   1.000 19.28300 ? 234  LYS A N   1 
ATOM   1473 C  CA  . LYS A  1 203 ? 22.70689 -27.15876 0.75903   1.000 21.38132 ? 234  LYS A CA  1 
ATOM   1474 C  C   . LYS A  1 203 ? 23.71138 -27.59530 -0.29159  1.000 21.39466 ? 234  LYS A C   1 
ATOM   1475 O  O   . LYS A  1 203 ? 24.22893 -28.71578 -0.23934  1.000 20.97684 ? 234  LYS A O   1 
ATOM   1476 C  CB  . LYS A  1 203 ? 21.29013 -27.21824 0.19740   1.000 22.02183 ? 234  LYS A CB  1 
ATOM   1477 C  CG  . LYS A  1 203 ? 20.89841 -28.58927 -0.30266  1.000 24.75691 ? 234  LYS A CG  1 
ATOM   1478 C  CD  . LYS A  1 203 ? 19.58305 -28.52869 -1.05779  1.000 25.87728 ? 234  LYS A CD  1 
ATOM   1479 C  CE  . LYS A  1 203 ? 19.06025 -29.92815 -1.32714  1.000 28.65681 ? 234  LYS A CE  1 
ATOM   1480 N  NZ  . LYS A  1 203 ? 17.97808 -29.92080 -2.35581  1.000 34.11557 ? 234  LYS A NZ  1 
ATOM   1481 N  N   . ASN A  1 204 ? 24.02445 -26.71756 -1.24303  1.000 19.03429 ? 235  ASN A N   1 
ATOM   1482 C  CA  . ASN A  1 204 ? 24.93806 -27.11847 -2.30532  1.000 19.43503 ? 235  ASN A CA  1 
ATOM   1483 C  C   . ASN A  1 204 ? 26.36852 -27.27202 -1.80289  1.000 21.20622 ? 235  ASN A C   1 
ATOM   1484 O  O   . ASN A  1 204 ? 27.10095 -28.13421 -2.30022  1.000 21.24541 ? 235  ASN A O   1 
ATOM   1485 C  CB  . ASN A  1 204 ? 24.84386 -26.13229 -3.46705  1.000 20.30239 ? 235  ASN A CB  1 
ATOM   1486 C  CG  . ASN A  1 204 ? 23.62771 -26.39491 -4.34014  1.000 27.52962 ? 235  ASN A CG  1 
ATOM   1487 O  OD1 . ASN A  1 204 ? 23.67679 -27.22104 -5.25860  1.000 30.96187 ? 235  ASN A OD1 1 
ATOM   1488 N  ND2 . ASN A  1 204 ? 22.52408 -25.72115 -4.04401  1.000 29.69110 ? 235  ASN A ND2 1 
ATOM   1489 N  N   . ILE A  1 205 ? 26.78238 -26.46728 -0.82166  1.000 19.79725 ? 236  ILE A N   1 
ATOM   1490 C  CA  . ILE A  1 205 ? 28.05757 -26.70844 -0.15143  1.000 18.79270 ? 236  ILE A CA  1 
ATOM   1491 C  C   . ILE A  1 205 ? 28.08869 -28.10977 0.45392   1.000 20.62014 ? 236  ILE A C   1 
ATOM   1492 O  O   . ILE A  1 205 ? 29.08153 -28.84024 0.31991   1.000 21.33316 ? 236  ILE A O   1 
ATOM   1493 C  CB  . ILE A  1 205 ? 28.29858 -25.62808 0.91721   1.000 18.97594 ? 236  ILE A CB  1 
ATOM   1494 C  CG1 . ILE A  1 205 ? 28.63025 -24.29822 0.23662   1.000 18.44372 ? 236  ILE A CG1 1 
ATOM   1495 C  CG2 . ILE A  1 205 ? 29.41323 -26.03746 1.85791   1.000 20.96341 ? 236  ILE A CG2 1 
ATOM   1496 C  CD1 . ILE A  1 205 ? 28.52609 -23.09125 1.15773   1.000 20.36341 ? 236  ILE A CD1 1 
ATOM   1497 N  N   . LYS A  1 206 ? 27.00228 -28.51127 1.11839   1.000 19.79600 ? 237  LYS A N   1 
ATOM   1498 C  CA  . LYS A  1 206 ? 26.97695 -29.84107 1.72965   1.000 21.17057 ? 237  LYS A CA  1 
ATOM   1499 C  C   . LYS A  1 206 ? 26.97365 -30.93913 0.67489   1.000 21.05715 ? 237  LYS A C   1 
ATOM   1500 O  O   . LYS A  1 206 ? 27.56582 -32.00472 0.88456   1.000 20.83605 ? 237  LYS A O   1 
ATOM   1501 C  CB  . LYS A  1 206 ? 25.76565 -29.98343 2.64567   1.000 23.43083 ? 237  LYS A CB  1 
ATOM   1502 C  CG  . LYS A  1 206 ? 25.87694 -29.18853 3.94044   1.000 24.59463 ? 237  LYS A CG  1 
ATOM   1503 C  CD  . LYS A  1 206 ? 24.57726 -29.29395 4.74303   1.000 27.37980 ? 237  LYS A CD  1 
ATOM   1504 C  CE  . LYS A  1 206 ? 24.64452 -28.50398 6.03478   1.000 32.84085 ? 237  LYS A CE  1 
ATOM   1505 N  NZ  . LYS A  1 206 ? 23.33673 -28.54481 6.74802   1.000 41.20368 ? 237  LYS A NZ  1 
ATOM   1506 N  N   . ILE A  1 207 ? 26.30830 -30.70091 -0.45880  1.000 20.76200 ? 238  ILE A N   1 
ATOM   1507 C  CA  . ILE A  1 207 ? 26.30373 -31.67538 -1.54585  1.000 21.44664 ? 238  ILE A CA  1 
ATOM   1508 C  C   . ILE A  1 207 ? 27.71542 -31.86861 -2.08499  1.000 22.53814 ? 238  ILE A C   1 
ATOM   1509 O  O   . ILE A  1 207 ? 28.18035 -33.00004 -2.27799  1.000 21.05686 ? 238  ILE A O   1 
ATOM   1510 C  CB  . ILE A  1 207 ? 25.33029 -31.23391 -2.65522  1.000 20.84100 ? 238  ILE A CB  1 
ATOM   1511 C  CG1 . ILE A  1 207 ? 23.88500 -31.30302 -2.15311  1.000 20.67983 ? 238  ILE A CG1 1 
ATOM   1512 C  CG2 . ILE A  1 207 ? 25.51991 -32.07812 -3.91717  1.000 23.31648 ? 238  ILE A CG2 1 
ATOM   1513 C  CD1 . ILE A  1 207 ? 22.87290 -30.64541 -3.08077  1.000 20.35855 ? 238  ILE A CD1 1 
ATOM   1514 N  N   . ALA A  1 208 ? 28.42632 -30.75987 -2.32328  1.000 20.21075 ? 239  ALA A N   1 
ATOM   1515 C  CA  . ALA A  1 208 ? 29.80154 -30.84868 -2.80334  1.000 22.78312 ? 239  ALA A CA  1 
ATOM   1516 C  C   . ALA A  1 208 ? 30.69097 -31.58306 -1.80774  1.000 22.37299 ? 239  ALA A C   1 
ATOM   1517 O  O   . ALA A  1 208 ? 31.54770 -32.38208 -2.20188  1.000 23.65553 ? 239  ALA A O   1 
ATOM   1518 C  CB  . ALA A  1 208 ? 30.35506 -29.44662 -3.07462  1.000 22.39848 ? 239  ALA A CB  1 
ATOM   1519 N  N   . ALA A  1 209 ? 30.50734 -31.32032 -0.51156  1.000 22.65640 ? 240  ALA A N   1 
ATOM   1520 C  CA  . ALA A  1 209 ? 31.31423 -31.99658 0.49736   1.000 23.66756 ? 240  ALA A CA  1 
ATOM   1521 C  C   . ALA A  1 209 ? 31.04857 -33.49758 0.49490   1.000 26.04675 ? 240  ALA A C   1 
ATOM   1522 O  O   . ALA A  1 209 ? 31.97878 -34.30257 0.64145   1.000 25.49600 ? 240  ALA A O   1 
ATOM   1523 C  CB  . ALA A  1 209 ? 31.03359 -31.40836 1.88270   1.000 25.06283 ? 240  ALA A CB  1 
ATOM   1524 N  N   . ALA A  1 210 ? 29.78355 -33.89089 0.33762   1.000 22.22183 ? 241  ALA A N   1 
ATOM   1525 C  CA  . ALA A  1 210 ? 29.45884 -35.31509 0.30506   1.000 24.04426 ? 241  ALA A CA  1 
ATOM   1526 C  C   . ALA A  1 210 ? 30.01703 -35.97512 -0.94843  1.000 22.98084 ? 241  ALA A C   1 
ATOM   1527 O  O   . ALA A  1 210 ? 30.44191 -37.13608 -0.90730  1.000 22.46347 ? 241  ALA A O   1 
ATOM   1528 C  CB  . ALA A  1 210 ? 27.94330 -35.52016 0.38822   1.000 22.92743 ? 241  ALA A CB  1 
ATOM   1529 N  N   . LYS A  1 211 ? 30.01033 -35.26050 -2.07427  1.000 21.26165 ? 242  LYS A N   1 
ATOM   1530 C  CA  . LYS A  1 211 ? 30.58049 -35.77514 -3.31297  1.000 23.69194 ? 242  LYS A CA  1 
ATOM   1531 C  C   . LYS A  1 211 ? 32.10187 -35.75906 -3.32138  1.000 25.98753 ? 242  LYS A C   1 
ATOM   1532 O  O   . LYS A  1 211 ? 32.69959 -36.40511 -4.19043  1.000 23.86058 ? 242  LYS A O   1 
ATOM   1533 C  CB  . LYS A  1 211 ? 30.07677 -34.96440 -4.50735  1.000 22.35232 ? 242  LYS A CB  1 
ATOM   1534 C  CG  . LYS A  1 211 ? 28.60108 -35.11306 -4.81853  1.000 23.55167 ? 242  LYS A CG  1 
ATOM   1535 C  CD  . LYS A  1 211 ? 28.21487 -34.09274 -5.88222  1.000 26.02803 ? 242  LYS A CD  1 
ATOM   1536 C  CE  . LYS A  1 211 ? 26.83467 -34.34838 -6.43893  1.000 33.55435 ? 242  LYS A CE  1 
ATOM   1537 N  NZ  . LYS A  1 211 ? 26.88357 -35.27898 -7.60047  1.000 42.71625 ? 242  LYS A NZ  1 
ATOM   1538 N  N   . LYS A  1 212 ? 32.72846 -35.04199 -2.38715  1.000 22.29841 ? 243  LYS A N   1 
ATOM   1539 C  CA  . LYS A  1 212 ? 34.17972 -34.83880 -2.37196  1.000 22.14850 ? 243  LYS A CA  1 
ATOM   1540 C  C   . LYS A  1 212 ? 34.65585 -34.30498 -3.71996  1.000 24.33073 ? 243  LYS A C   1 
ATOM   1541 O  O   . LYS A  1 212 ? 35.60845 -34.79848 -4.32752  1.000 28.45298 ? 243  LYS A O   1 
ATOM   1542 C  CB  . LYS A  1 212 ? 34.90900 -36.12806 -1.98182  1.000 27.76964 ? 243  LYS A CB  1 
ATOM   1543 C  CG  . LYS A  1 212 ? 34.54804 -36.62977 -0.58626  1.000 30.91558 ? 243  LYS A CG  1 
ATOM   1544 C  CD  . LYS A  1 212 ? 35.10448 -38.03685 -0.34644  1.000 43.06406 ? 243  LYS A CD  1 
ATOM   1545 C  CE  . LYS A  1 212 ? 34.58021 -38.65029 0.94550   1.000 44.91886 ? 243  LYS A CE  1 
ATOM   1546 N  NZ  . LYS A  1 212 ? 35.03351 -37.88567 2.13872   1.000 53.60346 ? 243  LYS A NZ  1 
ATOM   1547 N  N   . GLN A  1 213 ? 33.95832 -33.27795 -4.19186  1.000 24.42794 ? 244  GLN A N   1 
ATOM   1548 C  CA  . GLN A  1 213 ? 34.15397 -32.63843 -5.47367  1.000 23.91118 ? 244  GLN A CA  1 
ATOM   1549 C  C   . GLN A  1 213 ? 34.32152 -31.14568 -5.23040  1.000 21.10224 ? 244  GLN A C   1 
ATOM   1550 O  O   . GLN A  1 213 ? 33.57256 -30.57946 -4.43339  1.000 20.92221 ? 244  GLN A O   1 
ATOM   1551 C  CB  . GLN A  1 213 ? 32.92756 -32.89890 -6.36464  1.000 26.72107 ? 244  GLN A CB  1 
ATOM   1552 C  CG  . GLN A  1 213 ? 33.07950 -32.59446 -7.83050  1.000 26.07863 ? 244  GLN A CG  1 
ATOM   1553 C  CD  . GLN A  1 213 ? 31.81656 -32.93498 -8.61304  1.000 27.26128 ? 244  GLN A CD  1 
ATOM   1554 O  OE1 . GLN A  1 213 ? 30.82868 -33.41234 -8.04750  1.000 30.60091 ? 244  GLN A OE1 1 
ATOM   1555 N  NE2 . GLN A  1 213 ? 31.84346 -32.69136 -9.91659  1.000 27.19722 ? 244  GLN A NE2 1 
ATOM   1556 N  N   . PRO A  1 214 ? 35.28910 -30.48519 -5.86464  1.000 20.67617 ? 245  PRO A N   1 
ATOM   1557 C  CA  . PRO A  1 214 ? 35.37121 -29.02326 -5.72580  1.000 18.85263 ? 245  PRO A CA  1 
ATOM   1558 C  C   . PRO A  1 214 ? 34.11454 -28.38937 -6.29296  1.000 21.37107 ? 245  PRO A C   1 
ATOM   1559 O  O   . PRO A  1 214 ? 33.57009 -28.85293 -7.29676  1.000 21.63655 ? 245  PRO A O   1 
ATOM   1560 C  CB  . PRO A  1 214 ? 36.60993 -28.64537 -6.54611  1.000 24.38916 ? 245  PRO A CB  1 
ATOM   1561 C  CG  . PRO A  1 214 ? 36.81995 -29.78953 -7.48568  1.000 31.21507 ? 245  PRO A CG  1 
ATOM   1562 C  CD  . PRO A  1 214 ? 36.25002 -31.01985 -6.84633  1.000 25.77610 ? 245  PRO A CD  1 
ATOM   1563 N  N   . PHE A  1 215 ? 33.63349 -27.34061 -5.63038  1.000 20.18273 ? 246  PHE A N   1 
ATOM   1564 C  CA  . PHE A  1 215 ? 32.42331 -26.67781 -6.08713  1.000 21.88407 ? 246  PHE A CA  1 
ATOM   1565 C  C   . PHE A  1 215 ? 32.73483 -25.31349 -6.68391  1.000 19.27358 ? 246  PHE A C   1 
ATOM   1566 O  O   . PHE A  1 215 ? 33.73858 -24.67616 -6.35341  1.000 18.87546 ? 246  PHE A O   1 
ATOM   1567 C  CB  . PHE A  1 215 ? 31.37363 -26.52878 -4.96541  1.000 22.41392 ? 246  PHE A CB  1 
ATOM   1568 C  CG  . PHE A  1 215 ? 31.75319 -25.58335 -3.83017  1.000 21.19335 ? 246  PHE A CG  1 
ATOM   1569 C  CD1 . PHE A  1 215 ? 31.71392 -24.19947 -3.98766  1.000 19.66681 ? 246  PHE A CD1 1 
ATOM   1570 C  CD2 . PHE A  1 215 ? 32.05938 -26.09820 -2.57700  1.000 20.80961 ? 246  PHE A CD2 1 
ATOM   1571 C  CE1 . PHE A  1 215 ? 32.02494 -23.35407 -2.92347  1.000 19.93719 ? 246  PHE A CE1 1 
ATOM   1572 C  CE2 . PHE A  1 215 ? 32.36216 -25.26544 -1.50546  1.000 19.09198 ? 246  PHE A CE2 1 
ATOM   1573 C  CZ  . PHE A  1 215 ? 32.33683 -23.89145 -1.67826  1.000 20.35756 ? 246  PHE A CZ  1 
ATOM   1574 N  N   . PHE A  1 216 ? 31.85577 -24.89196 -7.58672  1.000 17.31911 ? 247  PHE A N   1 
ATOM   1575 C  CA  . PHE A  1 216 ? 31.74380 -23.50595 -8.01797  1.000 17.03450 ? 247  PHE A CA  1 
ATOM   1576 C  C   . PHE A  1 216 ? 30.30444 -23.09809 -7.77364  1.000 20.91646 ? 247  PHE A C   1 
ATOM   1577 O  O   . PHE A  1 216 ? 29.39413 -23.68695 -8.36042  1.000 20.32885 ? 247  PHE A O   1 
ATOM   1578 C  CB  . PHE A  1 216 ? 32.09951 -23.35610 -9.49936  1.000 17.77390 ? 247  PHE A CB  1 
ATOM   1579 C  CG  . PHE A  1 216 ? 31.78807 -22.00008 -10.05435 1.000 17.69934 ? 247  PHE A CG  1 
ATOM   1580 C  CD1 . PHE A  1 216 ? 32.54684 -20.90018 -9.68493  1.000 19.50963 ? 247  PHE A CD1 1 
ATOM   1581 C  CD2 . PHE A  1 216 ? 30.73708 -21.81776 -10.94327 1.000 19.29016 ? 247  PHE A CD2 1 
ATOM   1582 C  CE1 . PHE A  1 216 ? 32.26446 -19.64272 -10.20334 1.000 19.35907 ? 247  PHE A CE1 1 
ATOM   1583 C  CE2 . PHE A  1 216 ? 30.44847 -20.56011 -11.45613 1.000 20.95355 ? 247  PHE A CE2 1 
ATOM   1584 C  CZ  . PHE A  1 216 ? 31.21387 -19.47553 -11.08151 1.000 20.21845 ? 247  PHE A CZ  1 
ATOM   1585 N  N   . ILE A  1 217 ? 30.08995 -22.12969 -6.88489  1.000 16.13227 ? 248  ILE A N   1 
ATOM   1586 C  CA  . ILE A  1 217 ? 28.74689 -21.65513 -6.57510  1.000 16.96566 ? 248  ILE A CA  1 
ATOM   1587 C  C   . ILE A  1 217 ? 28.67051 -20.18646 -6.95954  1.000 17.84058 ? 248  ILE A C   1 
ATOM   1588 O  O   . ILE A  1 217 ? 29.47659 -19.37759 -6.49067  1.000 18.53251 ? 248  ILE A O   1 
ATOM   1589 C  CB  . ILE A  1 217 ? 28.39399 -21.85961 -5.09471  1.000 16.70632 ? 248  ILE A CB  1 
ATOM   1590 C  CG1 . ILE A  1 217 ? 28.33868 -23.36027 -4.78474  1.000 19.51292 ? 248  ILE A CG1 1 
ATOM   1591 C  CG2 . ILE A  1 217 ? 27.06791 -21.20316 -4.78042  1.000 18.03754 ? 248  ILE A CG2 1 
ATOM   1592 C  CD1 . ILE A  1 217 ? 28.14461 -23.67328 -3.31239  1.000 19.98612 ? 248  ILE A CD1 1 
ATOM   1593 N  N   . TYR A  1 218 ? 27.71952 -19.85992 -7.82901  1.000 18.69757 ? 249  TYR A N   1 
ATOM   1594 C  CA  . TYR A  1 218 ? 27.43991 -18.49714 -8.27039  1.000 17.21389 ? 249  TYR A CA  1 
ATOM   1595 C  C   . TYR A  1 218 ? 26.18062 -18.06842 -7.52072  1.000 18.02220 ? 249  TYR A C   1 
ATOM   1596 O  O   . TYR A  1 218 ? 25.06303 -18.41622 -7.91301  1.000 18.44325 ? 249  TYR A O   1 
ATOM   1597 C  CB  . TYR A  1 218 ? 27.26406 -18.47759 -9.78869  1.000 16.56235 ? 249  TYR A CB  1 
ATOM   1598 C  CG  . TYR A  1 218 ? 26.87366 -17.16349 -10.42522 1.000 16.70710 ? 249  TYR A CG  1 
ATOM   1599 C  CD1 . TYR A  1 218 ? 27.81132 -16.14698 -10.60167 1.000 17.94795 ? 249  TYR A CD1 1 
ATOM   1600 C  CD2 . TYR A  1 218 ? 25.57842 -16.94838 -10.88715 1.000 17.51224 ? 249  TYR A CD2 1 
ATOM   1601 C  CE1 . TYR A  1 218 ? 27.46346 -14.94893 -11.20948 1.000 19.16033 ? 249  TYR A CE1 1 
ATOM   1602 C  CE2 . TYR A  1 218 ? 25.21760 -15.75132 -11.49636 1.000 16.87519 ? 249  TYR A CE2 1 
ATOM   1603 C  CZ  . TYR A  1 218 ? 26.16667 -14.75641 -11.65588 1.000 15.77513 ? 249  TYR A CZ  1 
ATOM   1604 O  OH  . TYR A  1 218 ? 25.81077 -13.57301 -12.26929 1.000 17.97875 ? 249  TYR A OH  1 
ATOM   1605 N  N   . LEU A  1 219 ? 26.37377 -17.35398 -6.40554  1.000 16.81323 ? 250  LEU A N   1 
ATOM   1606 C  CA  . LEU A  1 219 ? 25.29547 -16.98167 -5.48900  1.000 17.57869 ? 250  LEU A CA  1 
ATOM   1607 C  C   . LEU A  1 219 ? 24.93523 -15.53129 -5.78299  1.000 16.33199 ? 250  LEU A C   1 
ATOM   1608 O  O   . LEU A  1 219 ? 25.57798 -14.59969 -5.29485  1.000 18.11183 ? 250  LEU A O   1 
ATOM   1609 C  CB  . LEU A  1 219 ? 25.72213 -17.19692 -4.03584  1.000 16.40983 ? 250  LEU A CB  1 
ATOM   1610 C  CG  . LEU A  1 219 ? 24.79599 -16.64964 -2.93799  1.000 17.85989 ? 250  LEU A CG  1 
ATOM   1611 C  CD1 . LEU A  1 219 ? 23.35856 -17.16737 -3.10053  1.000 19.49323 ? 250  LEU A CD1 1 
ATOM   1612 C  CD2 . LEU A  1 219 ? 25.36773 -17.03804 -1.56780  1.000 17.56432 ? 250  LEU A CD2 1 
ATOM   1613 N  N   . ALA A  1 220 ? 23.91768 -15.34779 -6.61500  1.000 15.17347 ? 251  ALA A N   1 
ATOM   1614 C  CA  . ALA A  1 220 ? 23.53705 -14.03109 -7.11835  1.000 16.10976 ? 251  ALA A CA  1 
ATOM   1615 C  C   . ALA A  1 220 ? 22.30216 -13.54594 -6.36538  1.000 16.08129 ? 251  ALA A C   1 
ATOM   1616 O  O   . ALA A  1 220 ? 21.17784 -13.61336 -6.85053  1.000 15.28141 ? 251  ALA A O   1 
ATOM   1617 C  CB  . ALA A  1 220 ? 23.28066 -14.10308 -8.61925  1.000 18.01407 ? 251  ALA A CB  1 
ATOM   1618 N  N   . TYR A  1 221 ? 22.52370 -13.04038 -5.15641  1.000 16.13506 ? 252  TYR A N   1 
ATOM   1619 C  CA  . TYR A  1 221 ? 21.43681 -12.40187 -4.41538  1.000 17.18628 ? 252  TYR A CA  1 
ATOM   1620 C  C   . TYR A  1 221 ? 20.81797 -11.26834 -5.22691  1.000 16.99914 ? 252  TYR A C   1 
ATOM   1621 O  O   . TYR A  1 221 ? 21.52779 -10.47390 -5.84491  1.000 16.85237 ? 252  TYR A O   1 
ATOM   1622 C  CB  . TYR A  1 221 ? 21.96391 -11.82018 -3.10532  1.000 16.20530 ? 252  TYR A CB  1 
ATOM   1623 C  CG  . TYR A  1 221 ? 22.36464 -12.81396 -2.03755  1.000 16.38310 ? 252  TYR A CG  1 
ATOM   1624 C  CD1 . TYR A  1 221 ? 21.39785 -13.53551 -1.34612  1.000 18.18877 ? 252  TYR A CD1 1 
ATOM   1625 C  CD2 . TYR A  1 221 ? 23.70047 -12.97126 -1.67193  1.000 18.05017 ? 252  TYR A CD2 1 
ATOM   1626 C  CE1 . TYR A  1 221 ? 21.75665 -14.43857 -0.33836  1.000 17.63080 ? 252  TYR A CE1 1 
ATOM   1627 C  CE2 . TYR A  1 221 ? 24.07791 -13.85511 -0.67213  1.000 17.95574 ? 252  TYR A CE2 1 
ATOM   1628 C  CZ  . TYR A  1 221 ? 23.09785 -14.58807 -0.01371  1.000 17.68289 ? 252  TYR A CZ  1 
ATOM   1629 O  OH  . TYR A  1 221 ? 23.45681 -15.45945 0.97969   1.000 18.38106 ? 252  TYR A OH  1 
ATOM   1630 N  N   . ASN A  1 222 ? 19.48839 -11.15257 -5.19332  1.000 16.20306 ? 253  ASN A N   1 
ATOM   1631 C  CA  . ASN A  1 222 ? 18.91784 -9.93730  -5.75988  1.000 17.52435 ? 253  ASN A CA  1 
ATOM   1632 C  C   . ASN A  1 222 ? 18.98130 -8.76198  -4.78912  1.000 15.95286 ? 253  ASN A C   1 
ATOM   1633 O  O   . ASN A  1 222 ? 18.83341 -7.61724  -5.21647  1.000 16.23698 ? 253  ASN A O   1 
ATOM   1634 C  CB  . ASN A  1 222 ? 17.47684 -10.16844 -6.26596  1.000 18.09537 ? 253  ASN A CB  1 
ATOM   1635 C  CG  . ASN A  1 222 ? 16.50016 -10.55052 -5.16947  1.000 17.88356 ? 253  ASN A CG  1 
ATOM   1636 O  OD1 . ASN A  1 222 ? 16.78410 -11.40393 -4.32762  1.000 19.05103 ? 253  ASN A OD1 1 
ATOM   1637 N  ND2 . ASN A  1 222 ? 15.31429 -9.93722  -5.20253  1.000 18.38029 ? 253  ASN A ND2 1 
ATOM   1638 N  N   . ALA A  1 223 ? 19.25085 -8.99152  -3.50885  1.000 17.01987 ? 254  ALA A N   1 
ATOM   1639 C  CA  . ALA A  1 223 ? 19.37375 -7.86808  -2.59298  1.000 16.35023 ? 254  ALA A CA  1 
ATOM   1640 C  C   . ALA A  1 223 ? 20.65691 -7.08396  -2.87854  1.000 16.50547 ? 254  ALA A C   1 
ATOM   1641 O  O   . ALA A  1 223 ? 21.66054 -7.66265  -3.30340  1.000 17.15830 ? 254  ALA A O   1 
ATOM   1642 C  CB  . ALA A  1 223 ? 19.38478 -8.36075  -1.14876  1.000 17.29017 ? 254  ALA A CB  1 
ATOM   1643 N  N   . PRO A  1 224 ? 20.65489 -5.76461  -2.64533  1.000 16.25916 ? 255  PRO A N   1 
ATOM   1644 C  CA  . PRO A  1 224 ? 19.53342 -4.90609  -2.21856  1.000 15.60965 ? 255  PRO A CA  1 
ATOM   1645 C  C   . PRO A  1 224 ? 18.78174 -4.20146  -3.35025  1.000 17.25403 ? 255  PRO A C   1 
ATOM   1646 O  O   . PRO A  1 224 ? 18.35172 -3.06649  -3.19678  1.000 16.83201 ? 255  PRO A O   1 
ATOM   1647 C  CB  . PRO A  1 224 ? 20.22861 -3.87383  -1.32732  1.000 17.80803 ? 255  PRO A CB  1 
ATOM   1648 C  CG  . PRO A  1 224 ? 21.56279 -3.66102  -2.03608  1.000 17.77239 ? 255  PRO A CG  1 
ATOM   1649 C  CD  . PRO A  1 224 ? 21.94694 -5.04166  -2.54968  1.000 16.53966 ? 255  PRO A CD  1 
ATOM   1650 N  N   . HIS A  1 225 ? 18.61881 -4.86410  -4.49130  1.000 14.85306 ? 256  HIS A N   1 
ATOM   1651 C  CA  . HIS A  1 225 ? 17.85955 -4.31227  -5.61128  1.000 16.24742 ? 256  HIS A CA  1 
ATOM   1652 C  C   . HIS A  1 225 ? 16.38458 -4.15394  -5.23776  1.000 20.47050 ? 256  HIS A C   1 
ATOM   1653 O  O   . HIS A  1 225 ? 15.82061 -4.94265  -4.47052  1.000 16.79300 ? 256  HIS A O   1 
ATOM   1654 C  CB  . HIS A  1 225 ? 18.02682 -5.25833  -6.81330  1.000 15.85926 ? 256  HIS A CB  1 
ATOM   1655 C  CG  . HIS A  1 225 ? 17.47427 -4.75924  -8.11665  1.000 17.40529 ? 256  HIS A CG  1 
ATOM   1656 N  ND1 . HIS A  1 225 ? 16.12508 -4.61679  -8.35552  1.000 17.52006 ? 256  HIS A ND1 1 
ATOM   1657 C  CD2 . HIS A  1 225 ? 18.09644 -4.48290  -9.29019  1.000 16.90046 ? 256  HIS A CD2 1 
ATOM   1658 C  CE1 . HIS A  1 225 ? 15.94300 -4.20389  -9.60143  1.000 19.02785 ? 256  HIS A CE1 1 
ATOM   1659 N  NE2 . HIS A  1 225 ? 17.12179 -4.12840  -10.19274 1.000 19.13285 ? 256  HIS A NE2 1 
ATOM   1660 N  N   . VAL A  1 226 ? 15.74675 -3.13406  -5.80385  1.000 17.07606 ? 257  VAL A N   1 
ATOM   1661 C  CA  . VAL A  1 226 ? 14.31740 -2.91336  -5.57550  1.000 16.71342 ? 257  VAL A CA  1 
ATOM   1662 C  C   . VAL A  1 226 ? 13.50611 -4.14458  -5.97469  1.000 17.92562 ? 257  VAL A C   1 
ATOM   1663 O  O   . VAL A  1 226 ? 13.93055 -4.93514  -6.83207  1.000 16.69739 ? 257  VAL A O   1 
ATOM   1664 C  CB  . VAL A  1 226 ? 13.82031 -1.67706  -6.33841  1.000 18.27452 ? 257  VAL A CB  1 
ATOM   1665 C  CG1 . VAL A  1 226 ? 14.40006 -0.39526  -5.73463  1.000 16.54291 ? 257  VAL A CG1 1 
ATOM   1666 C  CG2 . VAL A  1 226 ? 14.15721 -1.81847  -7.82665  1.000 19.23876 ? 257  VAL A CG2 1 
ATOM   1667 N  N   . PRO A  1 227 ? 12.32247 -4.35120  -5.38793  1.000 17.16701 ? 258  PRO A N   1 
ATOM   1668 C  CA  . PRO A  1 227 ? 11.63504 -3.50417  -4.39887  1.000 19.87616 ? 258  PRO A CA  1 
ATOM   1669 C  C   . PRO A  1 227 ? 12.29917 -3.54351  -3.03096  1.000 16.99631 ? 258  PRO A C   1 
ATOM   1670 O  O   . PRO A  1 227 ? 12.82393 -4.58266  -2.63100  1.000 17.54990 ? 258  PRO A O   1 
ATOM   1671 C  CB  . PRO A  1 227 ? 10.22260 -4.10699  -4.35959  1.000 23.16362 ? 258  PRO A CB  1 
ATOM   1672 C  CG  . PRO A  1 227 ? 10.43570 -5.56482  -4.68291  1.000 19.78978 ? 258  PRO A CG  1 
ATOM   1673 C  CD  . PRO A  1 227 ? 11.54176 -5.56243  -5.72246  1.000 16.28217 ? 258  PRO A CD  1 
ATOM   1674 N  N   . LEU A  1 228 ? 12.29332 -2.42109  -2.31132  1.000 18.01636 ? 259  LEU A N   1 
ATOM   1675 C  CA  . LEU A  1 228 ? 12.85234 -2.38049  -0.96151  1.000 16.77768 ? 259  LEU A CA  1 
ATOM   1676 C  C   . LEU A  1 228 ? 11.87981 -3.09402  -0.02756  1.000 18.85368 ? 259  LEU A C   1 
ATOM   1677 O  O   . LEU A  1 228 ? 10.84042 -2.55083  0.35533   1.000 20.00471 ? 259  LEU A O   1 
ATOM   1678 C  CB  . LEU A  1 228 ? 13.11514 -0.94589  -0.52136  1.000 18.71578 ? 259  LEU A CB  1 
ATOM   1679 C  CG  . LEU A  1 228 ? 14.08826 -0.13761  -1.37822  1.000 19.27231 ? 259  LEU A CG  1 
ATOM   1680 C  CD1 . LEU A  1 228 ? 14.36694 1.22179   -0.74251  1.000 21.04424 ? 259  LEU A CD1 1 
ATOM   1681 C  CD2 . LEU A  1 228 ? 15.39597 -0.91351  -1.60946  1.000 20.43616 ? 259  LEU A CD2 1 
ATOM   1682 N  N   . GLN A  1 229 ? 12.21542 -4.33515  0.31088   1.000 17.43495 ? 260  GLN A N   1 
ATOM   1683 C  CA  . GLN A  1 229 ? 11.36330 -5.21851  1.09835   1.000 18.11947 ? 260  GLN A CA  1 
ATOM   1684 C  C   . GLN A  1 229 ? 12.26712 -5.97304  2.05297   1.000 23.00466 ? 260  GLN A C   1 
ATOM   1685 O  O   . GLN A  1 229 ? 13.22896 -6.61128  1.61577   1.000 18.47115 ? 260  GLN A O   1 
ATOM   1686 C  CB  . GLN A  1 229 ? 10.58863 -6.18910  0.20727   1.000 19.46981 ? 260  GLN A CB  1 
ATOM   1687 C  CG  . GLN A  1 229 ? 9.63076  -5.48984  -0.74699  1.000 18.33968 ? 260  GLN A CG  1 
ATOM   1688 C  CD  . GLN A  1 229 ? 8.84302  -6.45362  -1.61117  1.000 18.07463 ? 260  GLN A CD  1 
ATOM   1689 O  OE1 . GLN A  1 229 ? 9.21351  -7.62163  -1.77966  1.000 20.22971 ? 260  GLN A OE1 1 
ATOM   1690 N  NE2 . GLN A  1 229 ? 7.73812  -5.96427  -2.17030  1.000 21.93615 ? 260  GLN A NE2 1 
ATOM   1691 N  N   . ALA A  1 230 ? 11.97488 -5.88925  3.34841   1.000 19.49995 ? 261  ALA A N   1 
ATOM   1692 C  CA  . ALA A  1 230 ? 12.85590 -6.45369  4.35852   1.000 19.32075 ? 261  ALA A CA  1 
ATOM   1693 C  C   . ALA A  1 230 ? 12.02491 -7.10422  5.45141   1.000 20.64555 ? 261  ALA A C   1 
ATOM   1694 O  O   . ALA A  1 230 ? 10.86420 -6.74817  5.66862   1.000 22.52582 ? 261  ALA A O   1 
ATOM   1695 C  CB  . ALA A  1 230 ? 13.77269 -5.38424  4.96846   1.000 19.88903 ? 261  ALA A CB  1 
ATOM   1696 N  N   . LYS A  1 231 ? 12.65488 -8.05052  6.14409   1.000 18.99947 ? 262  LYS A N   1 
ATOM   1697 C  CA  . LYS A  1 231 ? 12.03604 -8.71163  7.28887   1.000 19.00053 ? 262  LYS A CA  1 
ATOM   1698 C  C   . LYS A  1 231 ? 11.96728 -7.76396  8.47643   1.000 19.67865 ? 262  LYS A C   1 
ATOM   1699 O  O   . LYS A  1 231 ? 12.89373 -6.99710  8.73017   1.000 20.15999 ? 262  LYS A O   1 
ATOM   1700 C  CB  . LYS A  1 231 ? 12.83642 -9.95248  7.68425   1.000 20.68219 ? 262  LYS A CB  1 
ATOM   1701 C  CG  . LYS A  1 231 ? 12.98513 -11.00938 6.59849   1.000 22.39533 ? 262  LYS A CG  1 
ATOM   1702 C  CD  . LYS A  1 231 ? 14.01950 -12.05573 6.99678   1.000 24.93211 ? 262  LYS A CD  1 
ATOM   1703 C  CE  . LYS A  1 231 ? 13.48537 -12.99821 8.05155   1.000 25.96302 ? 262  LYS A CE  1 
ATOM   1704 N  NZ  . LYS A  1 231 ? 14.57530 -13.93704 8.50911   1.000 24.59233 ? 262  LYS A NZ  1 
ATOM   1705 N  N   . ALA A  1 232 ? 10.85890 -7.82708  9.22025   1.000 21.85430 ? 263  ALA A N   1 
ATOM   1706 C  CA  . ALA A  1 232 ? 10.73293 -6.97861  10.40365  1.000 23.77939 ? 263  ALA A CA  1 
ATOM   1707 C  C   . ALA A  1 232 ? 11.87471 -7.21717  11.38731  1.000 21.92063 ? 263  ALA A C   1 
ATOM   1708 O  O   . ALA A  1 232 ? 12.36548 -6.27056  12.01896  1.000 24.16139 ? 263  ALA A O   1 
ATOM   1709 C  CB  . ALA A  1 232 ? 9.38533  -7.22214  11.08248  1.000 28.77712 ? 263  ALA A CB  1 
ATOM   1710 N  N   . GLU A  1 233 ? 12.30909 -8.47306  11.52863  1.000 24.08760 ? 264  GLU A N   1 
ATOM   1711 C  CA  . GLU A  1 233 ? 13.39303 -8.80085  12.45614  1.000 23.20538 ? 264  GLU A CA  1 
ATOM   1712 C  C   . GLU A  1 233 ? 14.68719 -8.08958  12.07538  1.000 24.97163 ? 264  GLU A C   1 
ATOM   1713 O  O   . GLU A  1 233 ? 15.46650 -7.67404  12.94362  1.000 22.66343 ? 264  GLU A O   1 
ATOM   1714 C  CB  . GLU A  1 233 ? 13.60213 -10.31789 12.48680  1.000 28.34585 ? 264  GLU A CB  1 
ATOM   1715 C  CG  . GLU A  1 233 ? 12.39219 -11.12187 12.97901  1.000 37.54791 ? 264  GLU A CG  1 
ATOM   1716 C  CD  . GLU A  1 233 ? 11.39786 -11.53056 11.88072  1.000 40.32933 ? 264  GLU A CD  1 
ATOM   1717 O  OE1 . GLU A  1 233 ? 11.38364 -10.93998 10.77149  1.000 27.76344 ? 264  GLU A OE1 1 
ATOM   1718 O  OE2 . GLU A  1 233 ? 10.60344 -12.45799 12.14789  1.000 44.97662 ? 264  GLU A OE2 1 
ATOM   1719 N  N   . ASP A  1 234 ? 14.93797 -7.94081  10.77717  1.000 21.40770 ? 265  ASP A N   1 
ATOM   1720 C  CA  . ASP A  1 234 ? 16.13182 -7.22983  10.33894  1.000 20.29643 ? 265  ASP A CA  1 
ATOM   1721 C  C   . ASP A  1 234 ? 15.96313 -5.71787  10.45779  1.000 19.69983 ? 265  ASP A C   1 
ATOM   1722 O  O   . ASP A  1 234 ? 16.89441 -5.02203  10.87455  1.000 20.82042 ? 265  ASP A O   1 
ATOM   1723 C  CB  . ASP A  1 234 ? 16.46386 -7.60940  8.89730   1.000 18.82796 ? 265  ASP A CB  1 
ATOM   1724 C  CG  . ASP A  1 234 ? 16.87720 -9.05847  8.75634   1.000 21.81136 ? 265  ASP A CG  1 
ATOM   1725 O  OD1 . ASP A  1 234 ? 17.45900 -9.62058  9.71454   1.000 24.27863 ? 265  ASP A OD1 1 
ATOM   1726 O  OD2 . ASP A  1 234 ? 16.61932 -9.63403  7.68130   1.000 21.77977 ? 265  ASP A OD2 1 
ATOM   1727 N  N   . VAL A  1 235 ? 14.79192 -5.19035  10.08117  1.000 19.73866 ? 266  VAL A N   1 
ATOM   1728 C  CA  . VAL A  1 235 ? 14.53639 -3.75436  10.19093  1.000 20.91835 ? 266  VAL A CA  1 
ATOM   1729 C  C   . VAL A  1 235 ? 14.70163 -3.28294  11.62790  1.000 19.18236 ? 266  VAL A C   1 
ATOM   1730 O  O   . VAL A  1 235 ? 15.18009 -2.16925  11.87632  1.000 21.82531 ? 266  VAL A O   1 
ATOM   1731 C  CB  . VAL A  1 235 ? 13.12596 -3.42854  9.65372   1.000 21.06632 ? 266  VAL A CB  1 
ATOM   1732 C  CG1 . VAL A  1 235 ? 12.74511 -1.98483  9.95075   1.000 23.22130 ? 266  VAL A CG1 1 
ATOM   1733 C  CG2 . VAL A  1 235 ? 13.04750 -3.69848  8.15659   1.000 24.10516 ? 266  VAL A CG2 1 
ATOM   1734 N  N   . ALA A  1 236 ? 14.34535 -4.13833  12.59351  1.000 22.39812 ? 267  ALA A N   1 
ATOM   1735 C  CA  . ALA A  1 236 ? 14.42756 -3.76624  14.00398  1.000 23.52298 ? 267  ALA A CA  1 
ATOM   1736 C  C   . ALA A  1 236 ? 15.84996 -3.44623  14.42860  1.000 25.52257 ? 267  ALA A C   1 
ATOM   1737 O  O   . ALA A  1 236 ? 16.05938 -2.67221  15.37024  1.000 25.77773 ? 267  ALA A O   1 
ATOM   1738 C  CB  . ALA A  1 236 ? 13.86796 -4.89455  14.87120  1.000 23.44019 ? 267  ALA A CB  1 
ATOM   1739 N  N   . LYS A  1 237 ? 16.83535 -4.02896  13.76029  1.000 22.41137 ? 268  LYS A N   1 
ATOM   1740 C  CA  . LYS A  1 237 ? 18.22067 -3.77089  14.10155  1.000 22.59270 ? 268  LYS A CA  1 
ATOM   1741 C  C   . LYS A  1 237 ? 18.71281 -2.44375  13.54718  1.000 22.50703 ? 268  LYS A C   1 
ATOM   1742 O  O   . LYS A  1 237 ? 19.84784 -2.05668  13.83849  1.000 22.92850 ? 268  LYS A O   1 
ATOM   1743 C  CB  . LYS A  1 237 ? 19.09670 -4.92091  13.60296  1.000 23.51416 ? 268  LYS A CB  1 
ATOM   1744 C  CG  . LYS A  1 237 ? 18.75274 -6.23904  14.30129  1.000 24.61141 ? 268  LYS A CG  1 
ATOM   1745 C  CD  . LYS A  1 237 ? 19.83847 -7.27349  14.16550  1.000 30.83367 ? 268  LYS A CD  1 
ATOM   1746 C  CE  . LYS A  1 237 ? 19.69016 -8.31870  15.25431  1.000 38.06075 ? 268  LYS A CE  1 
ATOM   1747 N  NZ  . LYS A  1 237 ? 18.26105 -8.67493  15.47529  1.000 38.99608 ? 268  LYS A NZ  1 
ATOM   1748 N  N   . PHE A  1 238 ? 17.88527 -1.73429  12.77622  1.000 21.24055 ? 269  PHE A N   1 
ATOM   1749 C  CA  . PHE A  1 238 ? 18.28267 -0.46805  12.17095  1.000 20.44364 ? 269  PHE A CA  1 
ATOM   1750 C  C   . PHE A  1 238 ? 17.33819 0.66632   12.54275  1.000 25.92390 ? 269  PHE A C   1 
ATOM   1751 O  O   . PHE A  1 238 ? 17.14742 1.61140   11.77340  1.000 23.79955 ? 269  PHE A O   1 
ATOM   1752 C  CB  . PHE A  1 238 ? 18.41459 -0.63562  10.65558  1.000 18.60873 ? 269  PHE A CB  1 
ATOM   1753 C  CG  . PHE A  1 238 ? 19.51665 -1.57743  10.29605  1.000 19.07397 ? 269  PHE A CG  1 
ATOM   1754 C  CD1 . PHE A  1 238 ? 20.82991 -1.14505  10.30978  1.000 19.95200 ? 269  PHE A CD1 1 
ATOM   1755 C  CD2 . PHE A  1 238 ? 19.25293 -2.90797  10.03814  1.000 20.08633 ? 269  PHE A CD2 1 
ATOM   1756 C  CE1 . PHE A  1 238 ? 21.86446 -2.02396  10.03582  1.000 20.60626 ? 269  PHE A CE1 1 
ATOM   1757 C  CE2 . PHE A  1 238 ? 20.27263 -3.79345  9.76874   1.000 21.74952 ? 269  PHE A CE2 1 
ATOM   1758 C  CZ  . PHE A  1 238 ? 21.58337 -3.34683  9.75793   1.000 21.64554 ? 269  PHE A CZ  1 
ATOM   1759 N  N   . ALA A  1 239 ? 16.77869 0.61006   13.75513  1.000 26.79647 ? 270  ALA A N   1 
ATOM   1760 C  CA  . ALA A  1 239 ? 15.99793 1.73737   14.24864  1.000 32.09964 ? 270  ALA A CA  1 
ATOM   1761 C  C   . ALA A  1 239 ? 16.82728 3.01404   14.36167  1.000 28.60230 ? 270  ALA A C   1 
ATOM   1762 O  O   . ALA A  1 239 ? 16.25364 4.10461   14.42901  1.000 41.37409 ? 270  ALA A O   1 
ATOM   1763 C  CB  . ALA A  1 239 ? 15.37490 1.38730   15.60318  1.000 39.19730 ? 270  ALA A CB  1 
ATOM   1764 N  N   . HIS A  1 240 ? 18.15893 2.91545   14.36772  1.000 37.80679 ? 271  HIS A N   1 
ATOM   1765 C  CA  . HIS A  1 240 ? 18.97691 4.12525   14.40126  1.000 34.90698 ? 271  HIS A CA  1 
ATOM   1766 C  C   . HIS A  1 240 ? 18.99446 4.87184   13.07040  1.000 39.99744 ? 271  HIS A C   1 
ATOM   1767 O  O   . HIS A  1 240 ? 19.69908 5.88586   12.96192  1.000 39.33479 ? 271  HIS A O   1 
ATOM   1768 C  CB  . HIS A  1 240 ? 20.41192 3.79733   14.82566  1.000 33.87199 ? 271  HIS A CB  1 
ATOM   1769 C  CG  . HIS A  1 240 ? 21.11452 2.81546   13.93551  1.000 30.95825 ? 271  HIS A CG  1 
ATOM   1770 N  ND1 . HIS A  1 240 ? 20.86135 1.46307   13.97707  1.000 29.28922 ? 271  HIS A ND1 1 
ATOM   1771 C  CD2 . HIS A  1 240 ? 22.09354 2.98527   13.01431  1.000 37.78057 ? 271  HIS A CD2 1 
ATOM   1772 C  CE1 . HIS A  1 240 ? 21.63722 0.84099   13.10567  1.000 36.20663 ? 271  HIS A CE1 1 
ATOM   1773 N  NE2 . HIS A  1 240 ? 22.39683 1.74263   12.50691  1.000 36.11198 ? 271  HIS A NE2 1 
ATOM   1774 N  N   . ILE A  1 241 ? 18.23765 4.41665   12.07330  1.000 33.14320 ? 272  ILE A N   1 
ATOM   1775 C  CA  . ILE A  1 241 ? 18.20955 5.02836   10.74860  1.000 29.31190 ? 272  ILE A CA  1 
ATOM   1776 C  C   . ILE A  1 241 ? 16.82938 5.63286   10.52579  1.000 29.12973 ? 272  ILE A C   1 
ATOM   1777 O  O   . ILE A  1 241 ? 15.83093 4.90762   10.43606  1.000 27.71625 ? 272  ILE A O   1 
ATOM   1778 C  CB  . ILE A  1 241 ? 18.54971 4.01225   9.64953   1.000 26.97997 ? 272  ILE A CB  1 
ATOM   1779 C  CG1 . ILE A  1 241 ? 19.94582 3.42052   9.87721   1.000 28.03699 ? 272  ILE A CG1 1 
ATOM   1780 C  CG2 . ILE A  1 241 ? 18.45572 4.67542   8.28118   1.000 23.84530 ? 272  ILE A CG2 1 
ATOM   1781 C  CD1 . ILE A  1 241 ? 20.39935 2.46082   8.78583   1.000 26.89562 ? 272  ILE A CD1 1 
ATOM   1782 N  N   . LYS A  1 242 ? 16.77892 6.96461   10.40117  1.000 32.04154 ? 273  LYS A N   1 
ATOM   1783 C  CA  . LYS A  1 242 ? 15.50303 7.67037   10.32636  1.000 33.92993 ? 273  LYS A CA  1 
ATOM   1784 C  C   . LYS A  1 242 ? 14.85125 7.54303   8.95284   1.000 27.39778 ? 273  LYS A C   1 
ATOM   1785 O  O   . LYS A  1 242 ? 13.62456 7.40440   8.85496   1.000 33.43004 ? 273  LYS A O   1 
ATOM   1786 C  CB  . LYS A  1 242 ? 15.70654 9.14777   10.67320  1.000 33.02454 ? 273  LYS A CB  1 
ATOM   1787 N  N   . ASP A  1 243 ? 15.64613 7.60559   7.88628   1.000 26.39476 ? 274  ASP A N   1 
ATOM   1788 C  CA  . ASP A  1 243 ? 15.10099 7.52513   6.53470   1.000 26.21373 ? 274  ASP A CA  1 
ATOM   1789 C  C   . ASP A  1 243 ? 14.59411 6.11425   6.24890   1.000 26.29570 ? 274  ASP A C   1 
ATOM   1790 O  O   . ASP A  1 243 ? 15.34546 5.13895   6.36408   1.000 23.87559 ? 274  ASP A O   1 
ATOM   1791 C  CB  . ASP A  1 243 ? 16.15916 7.93342   5.51571   1.000 25.33970 ? 274  ASP A CB  1 
ATOM   1792 C  CG  . ASP A  1 243 ? 15.64617 7.86204   4.09321   1.000 30.89437 ? 274  ASP A CG  1 
ATOM   1793 O  OD1 . ASP A  1 243 ? 14.93505 8.79633   3.67243   1.000 34.32099 ? 274  ASP A OD1 1 
ATOM   1794 O  OD2 . ASP A  1 243 ? 15.92973 6.86209   3.40121   1.000 25.86357 ? 274  ASP A OD2 1 
ATOM   1795 N  N   . LYS A  1 244 ? 13.32309 6.00632   5.85291   1.000 23.56546 ? 275  LYS A N   1 
ATOM   1796 C  CA  . LYS A  1 244 ? 12.69824 4.69494   5.72181   1.000 23.09737 ? 275  LYS A CA  1 
ATOM   1797 C  C   . LYS A  1 244 ? 13.37569 3.85077   4.64469   1.000 21.39024 ? 275  LYS A C   1 
ATOM   1798 O  O   . LYS A  1 244 ? 13.60152 2.65157   4.83819   1.000 23.54240 ? 275  LYS A O   1 
ATOM   1799 C  CB  . LYS A  1 244 ? 11.20750 4.84761   5.41803   1.000 27.55943 ? 275  LYS A CB  1 
ATOM   1800 C  CG  . LYS A  1 244 ? 10.49887 3.51467   5.19504   1.000 33.31428 ? 275  LYS A CG  1 
ATOM   1801 C  CD  . LYS A  1 244 ? 8.98014  3.68117   5.19454   1.000 40.68954 ? 275  LYS A CD  1 
ATOM   1802 C  CE  . LYS A  1 244 ? 8.27828  2.33648   5.07933   1.000 45.47025 ? 275  LYS A CE  1 
ATOM   1803 N  NZ  . LYS A  1 244 ? 7.51698  1.98493   6.31535   1.000 57.24599 ? 275  LYS A NZ  1 
ATOM   1804 N  N   . ASP A  1 245 ? 13.69143 4.45338   3.49690   1.000 20.80412 ? 276  ASP A N   1 
ATOM   1805 C  CA  . ASP A  1 245 ? 14.32557 3.68570   2.43168   1.000 21.83527 ? 276  ASP A CA  1 
ATOM   1806 C  C   . ASP A  1 245 ? 15.71231 3.20711   2.84229   1.000 19.52291 ? 276  ASP A C   1 
ATOM   1807 O  O   . ASP A  1 245 ? 16.05961 2.03974   2.61083   1.000 19.80665 ? 276  ASP A O   1 
ATOM   1808 C  CB  . ASP A  1 245 ? 14.38970 4.51591   1.15208   1.000 22.35892 ? 276  ASP A CB  1 
ATOM   1809 C  CG  . ASP A  1 245 ? 13.07067 4.51795   0.39520   1.000 25.92393 ? 276  ASP A CG  1 
ATOM   1810 O  OD1 . ASP A  1 245 ? 12.12009 3.82290   0.81417   1.000 32.30644 ? 276  ASP A OD1 1 
ATOM   1811 O  OD2 . ASP A  1 245 ? 12.99373 5.19999   -0.63672  1.000 35.71453 ? 276  ASP A OD2 1 
ATOM   1812 N  N   . ARG A  1 246 ? 16.51080 4.07908   3.47304   1.000 19.16213 ? 277  ARG A N   1 
ATOM   1813 C  CA  . ARG A  1 246 ? 17.82280 3.65154   3.95815   1.000 18.43520 ? 277  ARG A CA  1 
ATOM   1814 C  C   . ARG A  1 246 ? 17.69708 2.54397   5.00265   1.000 20.30684 ? 277  ARG A C   1 
ATOM   1815 O  O   . ARG A  1 246 ? 18.48354 1.58554   5.01039   1.000 19.76160 ? 277  ARG A O   1 
ATOM   1816 C  CB  . ARG A  1 246 ? 18.58864 4.84321   4.53001   1.000 21.08899 ? 277  ARG A CB  1 
ATOM   1817 C  CG  . ARG A  1 246 ? 19.98399 4.51491   5.02648   1.000 20.15094 ? 277  ARG A CG  1 
ATOM   1818 C  CD  . ARG A  1 246 ? 20.88001 4.07437   3.87622   1.000 20.55672 ? 277  ARG A CD  1 
ATOM   1819 N  NE  . ARG A  1 246 ? 22.27142 3.93841   4.29491   1.000 20.07543 ? 277  ARG A NE  1 
ATOM   1820 C  CZ  . ARG A  1 246 ? 23.25598 3.59154   3.47850   1.000 21.41036 ? 277  ARG A CZ  1 
ATOM   1821 N  NH1 . ARG A  1 246 ? 23.02801 3.34739   2.19745   1.000 18.38756 ? 277  ARG A NH1 1 
ATOM   1822 N  NH2 . ARG A  1 246 ? 24.49677 3.48768   3.95754   1.000 20.12782 ? 277  ARG A NH2 1 
ATOM   1823 N  N   . ARG A  1 247 ? 16.71684 2.66503   5.89928   1.000 19.87126 ? 278  ARG A N   1 
ATOM   1824 C  CA  . ARG A  1 247 ? 16.51910 1.64443   6.92436   1.000 19.75755 ? 278  ARG A CA  1 
ATOM   1825 C  C   . ARG A  1 247 ? 16.15765 0.30092   6.30163   1.000 20.09844 ? 278  ARG A C   1 
ATOM   1826 O  O   . ARG A  1 247 ? 16.69823 -0.74396  6.68539   1.000 18.38716 ? 278  ARG A O   1 
ATOM   1827 C  CB  . ARG A  1 247 ? 15.43382 2.10089   7.90170   1.000 21.21843 ? 278  ARG A CB  1 
ATOM   1828 C  CG  . ARG A  1 247 ? 15.16348 1.11591   9.03077   1.000 20.94324 ? 278  ARG A CG  1 
ATOM   1829 C  CD  . ARG A  1 247 ? 14.17637 1.69770   10.04803  1.000 24.92626 ? 278  ARG A CD  1 
ATOM   1830 N  NE  . ARG A  1 247 ? 12.86127 1.94828   9.46724   1.000 29.70838 ? 278  ARG A NE  1 
ATOM   1831 C  CZ  . ARG A  1 247 ? 12.35081 3.15308   9.24211   1.000 30.47707 ? 278  ARG A CZ  1 
ATOM   1832 N  NH1 . ARG A  1 247 ? 13.02129 4.25663   9.53290   1.000 34.35003 ? 278  ARG A NH1 1 
ATOM   1833 N  NH2 . ARG A  1 247 ? 11.13208 3.25299   8.71932   1.000 32.25237 ? 278  ARG A NH2 1 
ATOM   1834 N  N   . THR A  1 248 ? 15.22414 0.30639   5.34751   1.000 18.03135 ? 279  THR A N   1 
ATOM   1835 C  CA  . THR A  1 248 ? 14.82022 -0.93445  4.70083   1.000 18.09460 ? 279  THR A CA  1 
ATOM   1836 C  C   . THR A  1 248 ? 15.97971 -1.53754  3.92011   1.000 16.16809 ? 279  THR A C   1 
ATOM   1837 O  O   . THR A  1 248 ? 16.24573 -2.74269  3.99356   1.000 16.68774 ? 279  THR A O   1 
ATOM   1838 C  CB  . THR A  1 248 ? 13.63931 -0.67008  3.77270   1.000 19.40349 ? 279  THR A CB  1 
ATOM   1839 O  OG1 . THR A  1 248 ? 12.57830 -0.05618  4.51682   1.000 21.17091 ? 279  THR A OG1 1 
ATOM   1840 C  CG2 . THR A  1 248 ? 13.15445 -1.97961  3.15527   1.000 19.40786 ? 279  THR A CG2 1 
ATOM   1841 N  N   . TYR A  1 249 ? 16.67565 -0.69449  3.16094   1.000 17.23084 ? 280  TYR A N   1 
ATOM   1842 C  CA  . TYR A  1 249 ? 17.83718 -1.13267  2.39296   1.000 17.05600 ? 280  TYR A CA  1 
ATOM   1843 C  C   . TYR A  1 249 ? 18.90775 -1.72895  3.30199   1.000 18.07474 ? 280  TYR A C   1 
ATOM   1844 O  O   . TYR A  1 249 ? 19.46407 -2.79683  3.01360   1.000 16.82831 ? 280  TYR A O   1 
ATOM   1845 C  CB  . TYR A  1 249 ? 18.35267 0.07566   1.61435   1.000 18.16291 ? 280  TYR A CB  1 
ATOM   1846 C  CG  . TYR A  1 249 ? 19.64426 -0.09636  0.86328   1.000 16.32784 ? 280  TYR A CG  1 
ATOM   1847 C  CD1 . TYR A  1 249 ? 20.86137 0.07964   1.50355   1.000 17.07748 ? 280  TYR A CD1 1 
ATOM   1848 C  CD2 . TYR A  1 249 ? 19.64474 -0.36889  -0.49164  1.000 16.99776 ? 280  TYR A CD2 1 
ATOM   1849 C  CE1 . TYR A  1 249 ? 22.05234 -0.05796  0.82137   1.000 18.33827 ? 280  TYR A CE1 1 
ATOM   1850 C  CE2 . TYR A  1 249 ? 20.83917 -0.48794  -1.18980  1.000 17.54404 ? 280  TYR A CE2 1 
ATOM   1851 C  CZ  . TYR A  1 249 ? 22.03232 -0.32597  -0.52867  1.000 17.68916 ? 280  TYR A CZ  1 
ATOM   1852 O  OH  . TYR A  1 249 ? 23.22294 -0.44552  -1.22386  1.000 18.42875 ? 280  TYR A OH  1 
ATOM   1853 N  N   . ALA A  1 250 ? 19.20105 -1.05347  4.41638   1.000 17.33269 ? 281  ALA A N   1 
ATOM   1854 C  CA  . ALA A  1 250 ? 20.16283 -1.58728  5.37842   1.000 17.38675 ? 281  ALA A CA  1 
ATOM   1855 C  C   . ALA A  1 250 ? 19.75492 -2.98178  5.84298   1.000 18.71854 ? 281  ALA A C   1 
ATOM   1856 O  O   . ALA A  1 250 ? 20.58383 -3.89788  5.92018   1.000 17.36892 ? 281  ALA A O   1 
ATOM   1857 C  CB  . ALA A  1 250 ? 20.28456 -0.63411  6.57049   1.000 16.08425 ? 281  ALA A CB  1 
ATOM   1858 N  N   . ALA A  1 251 ? 18.47438 -3.15839  6.17125   1.000 16.73748 ? 282  ALA A N   1 
ATOM   1859 C  CA  . ALA A  1 251 ? 17.99278 -4.46837  6.59760   1.000 17.59063 ? 282  ALA A CA  1 
ATOM   1860 C  C   . ALA A  1 251 ? 18.14431 -5.52008  5.50347   1.000 17.38172 ? 282  ALA A C   1 
ATOM   1861 O  O   . ALA A  1 251 ? 18.41343 -6.69120  5.80321   1.000 18.58069 ? 282  ALA A O   1 
ATOM   1862 C  CB  . ALA A  1 251 ? 16.53065 -4.35342  7.03321   1.000 19.57505 ? 282  ALA A CB  1 
ATOM   1863 N  N   . MET A  1 252 ? 17.98144 -5.12446  4.23483   1.000 17.35229 ? 283  MET A N   1 
ATOM   1864 C  CA  . MET A  1 252 ? 18.16384 -6.06037  3.12872   1.000 18.88742 ? 283  MET A CA  1 
ATOM   1865 C  C   . MET A  1 252 ? 19.60890 -6.52150  3.01717   1.000 18.05376 ? 283  MET A C   1 
ATOM   1866 O  O   . MET A  1 252 ? 19.86946 -7.70448  2.76016   1.000 17.00256 ? 283  MET A O   1 
ATOM   1867 C  CB  . MET A  1 252 ? 17.72464 -5.40951  1.81540   1.000 18.02745 ? 283  MET A CB  1 
ATOM   1868 C  CG  . MET A  1 252 ? 16.24100 -5.10248  1.76360   1.000 17.72952 ? 283  MET A CG  1 
ATOM   1869 S  SD  . MET A  1 252 ? 15.83847 -4.05744  0.34476   1.000 19.32319 ? 283  MET A SD  1 
ATOM   1870 C  CE  . MET A  1 252 ? 15.75141 -5.26144  -0.95871  1.000 18.66469 ? 283  MET A CE  1 
ATOM   1871 N  N   . VAL A  1 253 ? 20.55811 -5.59520  3.16384   1.000 16.71373 ? 284  VAL A N   1 
ATOM   1872 C  CA  . VAL A  1 253 ? 21.96898 -5.96712  3.14058   1.000 16.75164 ? 284  VAL A CA  1 
ATOM   1873 C  C   . VAL A  1 253 ? 22.30051 -6.83032  4.34611   1.000 16.36799 ? 284  VAL A C   1 
ATOM   1874 O  O   . VAL A  1 253 ? 23.05389 -7.80390  4.24250   1.000 15.76657 ? 284  VAL A O   1 
ATOM   1875 C  CB  . VAL A  1 253 ? 22.85041 -4.70377  3.08862   1.000 15.44277 ? 284  VAL A CB  1 
ATOM   1876 C  CG1 . VAL A  1 253 ? 24.32675 -5.06754  3.11878   1.000 17.95250 ? 284  VAL A CG1 1 
ATOM   1877 C  CG2 . VAL A  1 253 ? 22.52742 -3.89746  1.85270   1.000 17.81210 ? 284  VAL A CG2 1 
ATOM   1878 N  N   . TYR A  1 254 ? 21.73169 -6.49516  5.51153   1.000 16.32873 ? 285  TYR A N   1 
ATOM   1879 C  CA  . TYR A  1 254 ? 21.99184 -7.29443  6.70635   1.000 17.17948 ? 285  TYR A CA  1 
ATOM   1880 C  C   . TYR A  1 254 ? 21.52306 -8.73688  6.52543   1.000 18.94070 ? 285  TYR A C   1 
ATOM   1881 O  O   . TYR A  1 254 ? 22.17348 -9.67473  7.00616   1.000 18.55395 ? 285  TYR A O   1 
ATOM   1882 C  CB  . TYR A  1 254 ? 21.31830 -6.64389  7.91694   1.000 16.89269 ? 285  TYR A CB  1 
ATOM   1883 C  CG  . TYR A  1 254 ? 21.58545 -7.38287  9.20092   1.000 17.64346 ? 285  TYR A CG  1 
ATOM   1884 C  CD1 . TYR A  1 254 ? 22.81273 -7.27190  9.84323   1.000 20.97384 ? 285  TYR A CD1 1 
ATOM   1885 C  CD2 . TYR A  1 254 ? 20.61060 -8.19227  9.77659   1.000 21.35137 ? 285  TYR A CD2 1 
ATOM   1886 C  CE1 . TYR A  1 254 ? 23.06636 -7.96047  11.02168  1.000 22.34452 ? 285  TYR A CE1 1 
ATOM   1887 C  CE2 . TYR A  1 254 ? 20.85930 -8.88646  10.95396  1.000 22.74897 ? 285  TYR A CE2 1 
ATOM   1888 C  CZ  . TYR A  1 254 ? 22.08083 -8.75650  11.57214  1.000 26.30127 ? 285  TYR A CZ  1 
ATOM   1889 O  OH  . TYR A  1 254 ? 22.32946 -9.44155  12.74628  1.000 30.27850 ? 285  TYR A OH  1 
ATOM   1890 N  N   . ALA A  1 255 ? 20.41291 -8.94004  5.80502   1.000 16.32544 ? 286  ALA A N   1 
ATOM   1891 C  CA  . ALA A  1 255 ? 19.95171 -10.29404 5.52517   1.000 17.24775 ? 286  ALA A CA  1 
ATOM   1892 C  C   . ALA A  1 255 ? 20.97671 -11.07425 4.71362   1.000 17.39322 ? 286  ALA A C   1 
ATOM   1893 O  O   . ALA A  1 255 ? 21.17654 -12.27022 4.94362   1.000 16.60830 ? 286  ALA A O   1 
ATOM   1894 C  CB  . ALA A  1 255 ? 18.60363 -10.25424 4.80034   1.000 16.89764 ? 286  ALA A CB  1 
ATOM   1895 N  N   . VAL A  1 256 ? 21.62345 -10.41816 3.74455   1.000 16.12435 ? 287  VAL A N   1 
ATOM   1896 C  CA  . VAL A  1 256 ? 22.70724 -11.06862 3.00551   1.000 16.95498 ? 287  VAL A CA  1 
ATOM   1897 C  C   . VAL A  1 256 ? 23.83352 -11.44638 3.95623   1.000 15.73228 ? 287  VAL A C   1 
ATOM   1898 O  O   . VAL A  1 256 ? 24.34259 -12.57779 3.93407   1.000 17.21345 ? 287  VAL A O   1 
ATOM   1899 C  CB  . VAL A  1 256 ? 23.21044 -10.15298 1.87450   1.000 16.99588 ? 287  VAL A CB  1 
ATOM   1900 C  CG1 . VAL A  1 256 ? 24.51241 -10.69338 1.28164   1.000 16.32567 ? 287  VAL A CG1 1 
ATOM   1901 C  CG2 . VAL A  1 256 ? 22.12972 -10.00363 0.78574   1.000 18.21216 ? 287  VAL A CG2 1 
ATOM   1902 N  N   . ASP A  1 257 ? 24.21435 -10.51062 4.82710   1.000 15.77576 ? 288  ASP A N   1 
ATOM   1903 C  CA  . ASP A  1 257 ? 25.29601 -10.76960 5.76735   1.000 15.76543 ? 288  ASP A CA  1 
ATOM   1904 C  C   . ASP A  1 257 ? 24.97928 -11.96201 6.66847   1.000 18.29246 ? 288  ASP A C   1 
ATOM   1905 O  O   . ASP A  1 257 ? 25.85483 -12.79693 6.92920   1.000 17.15285 ? 288  ASP A O   1 
ATOM   1906 C  CB  . ASP A  1 257 ? 25.56748 -9.52332  6.60340   1.000 17.35286 ? 288  ASP A CB  1 
ATOM   1907 C  CG  . ASP A  1 257 ? 26.89172 -9.59799  7.31234   1.000 19.89749 ? 288  ASP A CG  1 
ATOM   1908 O  OD1 . ASP A  1 257 ? 27.92580 -9.38780  6.65373   1.000 18.76913 ? 288  ASP A OD1 1 
ATOM   1909 O  OD2 . ASP A  1 257 ? 26.89953 -9.87608  8.52859   1.000 19.23329 ? 288  ASP A OD2 1 
ATOM   1910 N  N   . ARG A  1 258 ? 23.73757 -12.05398 7.16075   1.000 18.84648 ? 289  ARG A N   1 
ATOM   1911 C  CA  . ARG A  1 258 ? 23.34147 -13.21868 7.94783   1.000 17.64308 ? 289  ARG A CA  1 
ATOM   1912 C  C   . ARG A  1 258 ? 23.56454 -14.50303 7.17119   1.000 18.84731 ? 289  ARG A C   1 
ATOM   1913 O  O   . ARG A  1 258 ? 24.07494 -15.49143 7.71332   1.000 20.07818 ? 289  ARG A O   1 
ATOM   1914 C  CB  . ARG A  1 258 ? 21.86871 -13.13459 8.34622   1.000 19.99429 ? 289  ARG A CB  1 
ATOM   1915 C  CG  . ARG A  1 258 ? 21.52849 -12.14357 9.43488   1.000 22.81996 ? 289  ARG A CG  1 
ATOM   1916 C  CD  . ARG A  1 258 ? 20.10588 -12.42885 9.94880   1.000 21.16509 ? 289  ARG A CD  1 
ATOM   1917 N  NE  . ARG A  1 258 ? 19.05566 -12.02155 9.01419   1.000 20.49164 ? 289  ARG A NE  1 
ATOM   1918 C  CZ  . ARG A  1 258 ? 18.44400 -12.84369 8.17596   1.000 20.47919 ? 289  ARG A CZ  1 
ATOM   1919 N  NH1 . ARG A  1 258 ? 18.75818 -14.12905 8.11632   1.000 21.46343 ? 289  ARG A NH1 1 
ATOM   1920 N  NH2 . ARG A  1 258 ? 17.49537 -12.36526 7.37286   1.000 20.12552 ? 289  ARG A NH2 1 
ATOM   1921 N  N   . GLY A  1 259 ? 23.15526 -14.51443 5.90194   1.000 18.88171 ? 290  GLY A N   1 
ATOM   1922 C  CA  . GLY A  1 259 ? 23.31850 -15.70894 5.09393   1.000 18.18141 ? 290  GLY A CA  1 
ATOM   1923 C  C   . GLY A  1 259 ? 24.77714 -16.05779 4.88941   1.000 18.08871 ? 290  GLY A C   1 
ATOM   1924 O  O   . GLY A  1 259 ? 25.15811 -17.23103 4.94576   1.000 19.34944 ? 290  GLY A O   1 
ATOM   1925 N  N   . VAL A  1 260 ? 25.61192 -15.04154 4.65576   1.000 17.04917 ? 291  VAL A N   1 
ATOM   1926 C  CA  . VAL A  1 260 ? 27.04762 -15.27412 4.52197   1.000 17.07551 ? 291  VAL A CA  1 
ATOM   1927 C  C   . VAL A  1 260 ? 27.60736 -15.89340 5.79594   1.000 18.06884 ? 291  VAL A C   1 
ATOM   1928 O  O   . VAL A  1 260 ? 28.43773 -16.80726 5.74210   1.000 19.13553 ? 291  VAL A O   1 
ATOM   1929 C  CB  . VAL A  1 260 ? 27.76397 -13.96415 4.14662   1.000 19.52427 ? 291  VAL A CB  1 
ATOM   1930 C  CG1 . VAL A  1 260 ? 29.26695 -14.11305 4.25823   1.000 20.23523 ? 291  VAL A CG1 1 
ATOM   1931 C  CG2 . VAL A  1 260 ? 27.37155 -13.55248 2.73174   1.000 20.53085 ? 291  VAL A CG2 1 
ATOM   1932 N  N   . GLY A  1 261 ? 27.14603 -15.42895 6.95985   1.000 19.77974 ? 292  GLY A N   1 
ATOM   1933 C  CA  . GLY A  1 261 ? 27.59286 -16.03061 8.20791   1.000 20.77948 ? 292  GLY A CA  1 
ATOM   1934 C  C   . GLY A  1 261 ? 27.24512 -17.50612 8.31175   1.000 21.00366 ? 292  GLY A C   1 
ATOM   1935 O  O   . GLY A  1 261 ? 28.07083 -18.32220 8.73715   1.000 20.27742 ? 292  GLY A O   1 
ATOM   1936 N  N   . LYS A  1 262 ? 26.01848 -17.87162 7.92947   1.000 18.69130 ? 293  LYS A N   1 
ATOM   1937 C  CA  . LYS A  1 262 ? 25.63244 -19.28031 7.96981   1.000 19.34825 ? 293  LYS A CA  1 
ATOM   1938 C  C   . LYS A  1 262 ? 26.41708 -20.09027 6.94842   1.000 21.58210 ? 293  LYS A C   1 
ATOM   1939 O  O   . LYS A  1 262 ? 26.77859 -21.24602 7.20603   1.000 20.51402 ? 293  LYS A O   1 
ATOM   1940 C  CB  . LYS A  1 262 ? 24.12957 -19.42220 7.73142   1.000 21.79711 ? 293  LYS A CB  1 
ATOM   1941 C  CG  . LYS A  1 262 ? 23.27412 -18.83816 8.85301   1.000 26.38107 ? 293  LYS A CG  1 
ATOM   1942 C  CD  . LYS A  1 262 ? 21.78939 -18.96080 8.52902   1.000 33.22424 ? 293  LYS A CD  1 
ATOM   1943 C  CE  . LYS A  1 262 ? 21.40684 -20.38531 8.18335   1.000 42.19653 ? 293  LYS A CE  1 
ATOM   1944 N  NZ  . LYS A  1 262 ? 21.41301 -21.28704 9.37246   1.000 49.11895 ? 293  LYS A NZ  1 
ATOM   1945 N  N   . ILE A  1 263 ? 26.69119 -19.49695 5.78293   1.000 18.52817 ? 294  ILE A N   1 
ATOM   1946 C  CA  . ILE A  1 263 ? 27.52041 -20.16369 4.77962   1.000 18.46018 ? 294  ILE A CA  1 
ATOM   1947 C  C   . ILE A  1 263 ? 28.91883 -20.42950 5.32420   1.000 19.14732 ? 294  ILE A C   1 
ATOM   1948 O  O   . ILE A  1 263 ? 29.48145 -21.51588 5.12647   1.000 19.58936 ? 294  ILE A O   1 
ATOM   1949 C  CB  . ILE A  1 263 ? 27.55773 -19.32092 3.49039   1.000 16.19271 ? 294  ILE A CB  1 
ATOM   1950 C  CG1 . ILE A  1 263 ? 26.24308 -19.48987 2.73086   1.000 19.21116 ? 294  ILE A CG1 1 
ATOM   1951 C  CG2 . ILE A  1 263 ? 28.77144 -19.68794 2.63377   1.000 18.22971 ? 294  ILE A CG2 1 
ATOM   1952 C  CD1 . ILE A  1 263 ? 25.94530 -18.35271 1.73703   1.000 20.61893 ? 294  ILE A CD1 1 
ATOM   1953 N  N   . VAL A  1 264 ? 29.50732 -19.44111 6.00510   1.000 18.68258 ? 295  VAL A N   1 
ATOM   1954 C  CA  . VAL A  1 264 ? 30.84080 -19.61200 6.57312   1.000 19.27352 ? 295  VAL A CA  1 
ATOM   1955 C  C   . VAL A  1 264 ? 30.83892 -20.72619 7.60844   1.000 21.91091 ? 295  VAL A C   1 
ATOM   1956 O  O   . VAL A  1 264 ? 31.73307 -21.57818 7.62279   1.000 19.79641 ? 295  VAL A O   1 
ATOM   1957 C  CB  . VAL A  1 264 ? 31.33321 -18.28419 7.17513   1.000 19.75809 ? 295  VAL A CB  1 
ATOM   1958 C  CG1 . VAL A  1 264 ? 32.53476 -18.50952 8.08169   1.000 20.62704 ? 295  VAL A CG1 1 
ATOM   1959 C  CG2 . VAL A  1 264 ? 31.67117 -17.29892 6.05686   1.000 20.31610 ? 295  VAL A CG2 1 
ATOM   1960 N  N   . GLN A  1 265 ? 29.82720 -20.74992 8.47887   1.000 19.87271 ? 296  GLN A N   1 
ATOM   1961 C  CA  . GLN A  1 265 ? 29.75148 -21.82661 9.46160   1.000 20.69326 ? 296  GLN A CA  1 
ATOM   1962 C  C   . GLN A  1 265 ? 29.66515 -23.18505 8.77828   1.000 22.42807 ? 296  GLN A C   1 
ATOM   1963 O  O   . GLN A  1 265 ? 30.28289 -24.15525 9.22841   1.000 22.93761 ? 296  GLN A O   1 
ATOM   1964 C  CB  . GLN A  1 265 ? 28.55476 -21.61141 10.38386  1.000 23.07534 ? 296  GLN A CB  1 
ATOM   1965 C  CG  . GLN A  1 265 ? 28.28379 -22.75472 11.35071  1.000 29.86447 ? 296  GLN A CG  1 
ATOM   1966 C  CD  . GLN A  1 265 ? 29.28889 -22.82170 12.48604  1.000 32.83135 ? 296  GLN A CD  1 
ATOM   1967 O  OE1 . GLN A  1 265 ? 30.11267 -21.92020 12.66565  1.000 31.19043 ? 296  GLN A OE1 1 
ATOM   1968 N  NE2 . GLN A  1 265 ? 29.22124 -23.89826 13.26651  1.000 35.19831 ? 296  GLN A NE2 1 
ATOM   1969 N  N   . THR A  1 266 ? 28.91386 -23.26526 7.67750   1.000 19.52038 ? 297  THR A N   1 
ATOM   1970 C  CA  . THR A  1 266 ? 28.79393 -24.51551 6.93444   1.000 21.93460 ? 297  THR A CA  1 
ATOM   1971 C  C   . THR A  1 266 ? 30.12551 -24.92490 6.31492   1.000 20.08989 ? 297  THR A C   1 
ATOM   1972 O  O   . THR A  1 266 ? 30.50864 -26.10030 6.37962   1.000 21.21867 ? 297  THR A O   1 
ATOM   1973 C  CB  . THR A  1 266 ? 27.71875 -24.37398 5.85532   1.000 19.89903 ? 297  THR A CB  1 
ATOM   1974 O  OG1 . THR A  1 266 ? 26.47549 -23.98741 6.46468   1.000 21.96394 ? 297  THR A OG1 1 
ATOM   1975 C  CG2 . THR A  1 266 ? 27.53744 -25.68614 5.09695   1.000 21.46585 ? 297  THR A CG2 1 
ATOM   1976 N  N   . LEU A  1 267 ? 30.84133 -23.97325 5.70738   1.000 19.04305 ? 298  LEU A N   1 
ATOM   1977 C  CA  . LEU A  1 267 ? 32.17484 -24.26472 5.18757   1.000 20.70803 ? 298  LEU A CA  1 
ATOM   1978 C  C   . LEU A  1 267 ? 33.09680 -24.77507 6.28398   1.000 21.08392 ? 298  LEU A C   1 
ATOM   1979 O  O   . LEU A  1 267 ? 33.92137 -25.66084 6.04406   1.000 21.38421 ? 298  LEU A O   1 
ATOM   1980 C  CB  . LEU A  1 267 ? 32.78342 -23.02082 4.53316   1.000 17.72574 ? 298  LEU A CB  1 
ATOM   1981 C  CG  . LEU A  1 267 ? 32.09531 -22.53155 3.25235   1.000 21.04256 ? 298  LEU A CG  1 
ATOM   1982 C  CD1 . LEU A  1 267 ? 32.60379 -21.15399 2.88420   1.000 18.53041 ? 298  LEU A CD1 1 
ATOM   1983 C  CD2 . LEU A  1 267 ? 32.34774 -23.52714 2.10835   1.000 18.39391 ? 298  LEU A CD2 1 
ATOM   1984 N  N   . LYS A  1 268 ? 32.99900 -24.20440 7.48727   1.000 22.27299 ? 299  LYS A N   1 
ATOM   1985 C  CA  . LYS A  1 268 ? 33.83727 -24.69057 8.57527   1.000 22.72198 ? 299  LYS A CA  1 
ATOM   1986 C  C   . LYS A  1 268 ? 33.43824 -26.10025 8.97595   1.000 24.05390 ? 299  LYS A C   1 
ATOM   1987 O  O   . LYS A  1 268 ? 34.30225 -26.96578 9.15153   1.000 24.31188 ? 299  LYS A O   1 
ATOM   1988 C  CB  . LYS A  1 268 ? 33.75850 -23.74402 9.76889   1.000 21.51014 ? 299  LYS A CB  1 
ATOM   1989 C  CG  . LYS A  1 268 ? 34.47586 -22.42640 9.54233   1.000 23.81387 ? 299  LYS A CG  1 
ATOM   1990 C  CD  . LYS A  1 268 ? 34.23410 -21.48228 10.69802  1.000 25.77968 ? 299  LYS A CD  1 
ATOM   1991 C  CE  . LYS A  1 268 ? 35.03058 -20.20395 10.51627  1.000 30.73489 ? 299  LYS A CE  1 
ATOM   1992 N  NZ  . LYS A  1 268 ? 34.66425 -19.19915 11.56068  1.000 33.03118 ? 299  LYS A NZ  1 
ATOM   1993 N  N   . GLU A  1 269 ? 32.13274 -26.35411 9.10368   1.000 22.08839 ? 300  GLU A N   1 
ATOM   1994 C  CA  . GLU A  1 269 ? 31.67146 -27.67488 9.52684   1.000 24.39345 ? 300  GLU A CA  1 
ATOM   1995 C  C   . GLU A  1 269 ? 32.08242 -28.75811 8.53963   1.000 26.53753 ? 300  GLU A C   1 
ATOM   1996 O  O   . GLU A  1 269 ? 32.43115 -29.87771 8.94070   1.000 26.09576 ? 300  GLU A O   1 
ATOM   1997 C  CB  . GLU A  1 269 ? 30.15626 -27.66372 9.69954   1.000 28.75480 ? 300  GLU A CB  1 
ATOM   1998 C  CG  . GLU A  1 269 ? 29.69921 -26.86066 10.90157  1.000 34.04945 ? 300  GLU A CG  1 
ATOM   1999 C  CD  . GLU A  1 269 ? 28.18826 -26.81270 11.03058  1.000 43.31448 ? 300  GLU A CD  1 
ATOM   2000 O  OE1 . GLU A  1 269 ? 27.49142 -27.28074 10.09892  1.000 47.83266 ? 300  GLU A OE1 1 
ATOM   2001 O  OE2 . GLU A  1 269 ? 27.69996 -26.30473 12.06623  1.000 49.84299 ? 300  GLU A OE2 1 
ATOM   2002 N  N   . THR A  1 270 ? 32.03585 -28.45524 7.24877   1.000 23.34572 ? 301  THR A N   1 
ATOM   2003 C  CA  . THR A  1 270 ? 32.37687 -29.43227 6.22482   1.000 23.69678 ? 301  THR A CA  1 
ATOM   2004 C  C   . THR A  1 270 ? 33.87000 -29.47053 5.92017   1.000 21.92752 ? 301  THR A C   1 
ATOM   2005 O  O   . THR A  1 270 ? 34.27848 -30.18997 5.00147   1.000 25.42162 ? 301  THR A O   1 
ATOM   2006 C  CB  . THR A  1 270 ? 31.60090 -29.14969 4.93307   1.000 24.19161 ? 301  THR A CB  1 
ATOM   2007 O  OG1 . THR A  1 270 ? 31.92433 -27.83910 4.44933   1.000 24.51062 ? 301  THR A OG1 1 
ATOM   2008 C  CG2 . THR A  1 270 ? 30.10383 -29.24555 5.16677   1.000 27.24143 ? 301  THR A CG2 1 
ATOM   2009 N  N   . LYS A  1 271 ? 34.67856 -28.70684 6.66101   1.000 22.63291 ? 302  LYS A N   1 
ATOM   2010 C  CA  . LYS A  1 271 ? 36.12062 -28.59319 6.45601   1.000 22.42088 ? 302  LYS A CA  1 
ATOM   2011 C  C   . LYS A  1 271 ? 36.46664 -28.14958 5.03367   1.000 24.99951 ? 302  LYS A C   1 
ATOM   2012 O  O   . LYS A  1 271 ? 37.49336 -28.54733 4.47295   1.000 27.51771 ? 302  LYS A O   1 
ATOM   2013 C  CB  . LYS A  1 271 ? 36.83953 -29.89888 6.82135   1.000 28.95639 ? 302  LYS A CB  1 
ATOM   2014 C  CG  . LYS A  1 271 ? 36.41746 -30.41337 8.19227   1.000 28.79549 ? 302  LYS A CG  1 
ATOM   2015 C  CD  . LYS A  1 271 ? 37.34756 -31.47993 8.72889   1.000 45.51380 ? 302  LYS A CD  1 
ATOM   2016 C  CE  . LYS A  1 271 ? 36.74710 -32.13641 9.96750   1.000 48.05567 ? 302  LYS A CE  1 
ATOM   2017 N  NZ  . LYS A  1 271 ? 36.91517 -33.62080 9.92079   1.000 45.97634 ? 302  LYS A NZ  1 
ATOM   2018 N  N   . GLN A  1 272 ? 35.62580 -27.29483 4.44970   1.000 21.10574 ? 303  GLN A N   1 
ATOM   2019 C  CA  . GLN A  1 272 ? 35.89627 -26.71650 3.14000   1.000 19.75684 ? 303  GLN A CA  1 
ATOM   2020 C  C   . GLN A  1 272 ? 36.36622 -25.26673 3.21382   1.000 22.49854 ? 303  GLN A C   1 
ATOM   2021 O  O   . GLN A  1 272 ? 36.76554 -24.70900 2.18503   1.000 25.77521 ? 303  GLN A O   1 
ATOM   2022 C  CB  . GLN A  1 272 ? 34.63865 -26.80536 2.25448   1.000 22.23576 ? 303  GLN A CB  1 
ATOM   2023 C  CG  . GLN A  1 272 ? 34.23420 -28.25252 1.88451   1.000 23.20354 ? 303  GLN A CG  1 
ATOM   2024 C  CD  . GLN A  1 272 ? 32.89864 -28.33891 1.15600   1.000 30.03129 ? 303  GLN A CD  1 
ATOM   2025 O  OE1 . GLN A  1 272 ? 32.82903 -28.67437 -0.03504  1.000 34.00408 ? 303  GLN A OE1 1 
ATOM   2026 N  NE2 . GLN A  1 272 ? 31.82964 -28.03802 1.87007   1.000 30.77005 ? 303  GLN A NE2 1 
ATOM   2027 N  N   . PHE A  1 273 ? 36.37328 -24.67159 4.40881   1.000 21.03138 ? 304  PHE A N   1 
ATOM   2028 C  CA  . PHE A  1 273 ? 36.58363 -23.23236 4.57093   1.000 20.03601 ? 304  PHE A CA  1 
ATOM   2029 C  C   . PHE A  1 273 ? 37.98485 -22.80474 4.13966   1.000 22.36957 ? 304  PHE A C   1 
ATOM   2030 O  O   . PHE A  1 273 ? 38.14818 -21.80972 3.42162   1.000 22.86066 ? 304  PHE A O   1 
ATOM   2031 C  CB  . PHE A  1 273 ? 36.31784 -22.86465 6.03598   1.000 21.62235 ? 304  PHE A CB  1 
ATOM   2032 C  CG  . PHE A  1 273 ? 36.39416 -21.39224 6.33770   1.000 22.68165 ? 304  PHE A CG  1 
ATOM   2033 C  CD1 . PHE A  1 273 ? 35.46672 -20.51246 5.81070   1.000 24.51224 ? 304  PHE A CD1 1 
ATOM   2034 C  CD2 . PHE A  1 273 ? 37.36817 -20.90145 7.18847   1.000 25.40653 ? 304  PHE A CD2 1 
ATOM   2035 C  CE1 . PHE A  1 273 ? 35.52865 -19.14968 6.11377   1.000 25.74104 ? 304  PHE A CE1 1 
ATOM   2036 C  CE2 . PHE A  1 273 ? 37.43292 -19.54179 7.49521   1.000 29.43760 ? 304  PHE A CE2 1 
ATOM   2037 C  CZ  . PHE A  1 273 ? 36.50951 -18.67651 6.96237   1.000 25.94312 ? 304  PHE A CZ  1 
ATOM   2038 N  N   . ASP A  1 274 ? 39.01284 -23.54994 4.55358   1.000 20.10079 ? 305  ASP A N   1 
ATOM   2039 C  CA  . ASP A  1 274 ? 40.37729 -23.08625 4.32825   1.000 23.31213 ? 305  ASP A CA  1 
ATOM   2040 C  C   . ASP A  1 274 ? 40.74529 -23.08653 2.85123   1.000 21.56852 ? 305  ASP A C   1 
ATOM   2041 O  O   . ASP A  1 274 ? 41.51578 -22.22488 2.40945   1.000 22.12092 ? 305  ASP A O   1 
ATOM   2042 C  CB  . ASP A  1 274 ? 41.36236 -23.93675 5.13564   1.000 26.15011 ? 305  ASP A CB  1 
ATOM   2043 C  CG  . ASP A  1 274 ? 41.46359 -23.49024 6.58587   1.000 38.14886 ? 305  ASP A CG  1 
ATOM   2044 O  OD1 . ASP A  1 274 ? 40.94159 -22.39652 6.92980   1.000 34.80816 ? 305  ASP A OD1 1 
ATOM   2045 O  OD2 . ASP A  1 274 ? 42.06769 -24.23724 7.38498   1.000 39.23513 ? 305  ASP A OD2 1 
ATOM   2046 N  N   . ASN A  1 275 ? 40.18181 -23.99934 2.06499   1.000 20.36307 ? 306  ASN A N   1 
ATOM   2047 C  CA  . ASN A  1 275 ? 40.50683 -24.09793 0.64429   1.000 21.67995 ? 306  ASN A CA  1 
ATOM   2048 C  C   . ASN A  1 275 ? 39.30591 -23.73959 -0.22462  1.000 22.91030 ? 306  ASN A C   1 
ATOM   2049 O  O   . ASN A  1 275 ? 39.05474 -24.34957 -1.26851  1.000 22.12557 ? 306  ASN A O   1 
ATOM   2050 C  CB  . ASN A  1 275 ? 41.03258 -25.48588 0.29236   1.000 21.41144 ? 306  ASN A CB  1 
ATOM   2051 C  CG  . ASN A  1 275 ? 41.76201 -25.50423 -1.04860  1.000 23.22135 ? 306  ASN A CG  1 
ATOM   2052 O  OD1 . ASN A  1 275 ? 42.33391 -24.50083 -1.46691  1.000 24.09231 ? 306  ASN A OD1 1 
ATOM   2053 N  ND2 . ASN A  1 275 ? 41.74375 -26.65251 -1.72311  1.000 25.73886 ? 306  ASN A ND2 1 
ATOM   2054 N  N   . THR A  1 276 ? 38.54488 -22.74235 0.21144   1.000 20.30013 ? 307  THR A N   1 
ATOM   2055 C  CA  . THR A  1 276 ? 37.53211 -22.10574 -0.62051  1.000 19.80443 ? 307  THR A CA  1 
ATOM   2056 C  C   . THR A  1 276 ? 37.97315 -20.67404 -0.87864  1.000 16.95747 ? 307  THR A C   1 
ATOM   2057 O  O   . THR A  1 276 ? 38.33834 -19.95786 0.05711   1.000 20.45761 ? 307  THR A O   1 
ATOM   2058 C  CB  . THR A  1 276 ? 36.15914 -22.11622 0.05988   1.000 19.15750 ? 307  THR A CB  1 
ATOM   2059 O  OG1 . THR A  1 276 ? 35.72180 -23.46922 0.24005   1.000 19.95068 ? 307  THR A OG1 1 
ATOM   2060 C  CG2 . THR A  1 276 ? 35.12659 -21.37183 -0.78205  1.000 17.65692 ? 307  THR A CG2 1 
ATOM   2061 N  N   . LEU A  1 277 ? 37.96187 -20.27093 -2.14183  1.000 18.39621 ? 308  LEU A N   1 
ATOM   2062 C  CA  . LEU A  1 277 ? 38.12233 -18.86809 -2.49151  1.000 17.77128 ? 308  LEU A CA  1 
ATOM   2063 C  C   . LEU A  1 277 ? 36.73112 -18.26007 -2.51898  1.000 18.70420 ? 308  LEU A C   1 
ATOM   2064 O  O   . LEU A  1 277 ? 35.89718 -18.65332 -3.34088  1.000 18.03166 ? 308  LEU A O   1 
ATOM   2065 C  CB  . LEU A  1 277 ? 38.81037 -18.70464 -3.84224  1.000 16.92523 ? 308  LEU A CB  1 
ATOM   2066 C  CG  . LEU A  1 277 ? 38.77026 -17.28322 -4.42144  1.000 19.29270 ? 308  LEU A CG  1 
ATOM   2067 C  CD1 . LEU A  1 277 ? 39.48235 -16.25466 -3.52751  1.000 18.55808 ? 308  LEU A CD1 1 
ATOM   2068 C  CD2 . LEU A  1 277 ? 39.36173 -17.29286 -5.84021  1.000 21.02731 ? 308  LEU A CD2 1 
ATOM   2069 N  N   . ILE A  1 278 ? 36.46338 -17.34291 -1.59652  1.000 18.23686 ? 309  ILE A N   1 
ATOM   2070 C  CA  . ILE A  1 278 ? 35.21891 -16.58624 -1.60051  1.000 16.75703 ? 309  ILE A CA  1 
ATOM   2071 C  C   . ILE A  1 278 ? 35.49414 -15.23522 -2.23835  1.000 16.62931 ? 309  ILE A C   1 
ATOM   2072 O  O   . ILE A  1 278 ? 36.36682 -14.48606 -1.77906  1.000 17.90069 ? 309  ILE A O   1 
ATOM   2073 C  CB  . ILE A  1 278 ? 34.65219 -16.41312 -0.18479  1.000 17.22366 ? 309  ILE A CB  1 
ATOM   2074 C  CG1 . ILE A  1 278 ? 34.45749 -17.77681 0.48781   1.000 18.06583 ? 309  ILE A CG1 1 
ATOM   2075 C  CG2 . ILE A  1 278 ? 33.34753 -15.61490 -0.25041  1.000 19.11493 ? 309  ILE A CG2 1 
ATOM   2076 C  CD1 . ILE A  1 278 ? 33.95117 -17.64822 1.92869   1.000 19.76171 ? 309  ILE A CD1 1 
ATOM   2077 N  N   . VAL A  1 279 ? 34.74650 -14.91499 -3.28843  1.000 18.45834 ? 310  VAL A N   1 
ATOM   2078 C  CA  . VAL A  1 279 ? 34.81019 -13.61042 -3.93579  1.000 16.89239 ? 310  VAL A CA  1 
ATOM   2079 C  C   . VAL A  1 279 ? 33.46035 -12.93779 -3.74082  1.000 18.35292 ? 310  VAL A C   1 
ATOM   2080 O  O   . VAL A  1 279 ? 32.43429 -13.45857 -4.19453  1.000 17.29486 ? 310  VAL A O   1 
ATOM   2081 C  CB  . VAL A  1 279 ? 35.14619 -13.71681 -5.43359  1.000 17.16879 ? 310  VAL A CB  1 
ATOM   2082 C  CG1 . VAL A  1 279 ? 35.16138 -12.32067 -6.07640  1.000 17.19514 ? 310  VAL A CG1 1 
ATOM   2083 C  CG2 . VAL A  1 279 ? 36.47822 -14.44267 -5.65543  1.000 17.23454 ? 310  VAL A CG2 1 
ATOM   2084 N  N   . PHE A  1 280 ? 33.46547 -11.77251 -3.09635  1.000 15.83808 ? 311  PHE A N   1 
ATOM   2085 C  CA  . PHE A  1 280 ? 32.25805 -10.99328 -2.86481  1.000 16.69907 ? 311  PHE A CA  1 
ATOM   2086 C  C   . PHE A  1 280 ? 32.34186 -9.70907  -3.67240  1.000 15.51524 ? 311  PHE A C   1 
ATOM   2087 O  O   . PHE A  1 280 ? 33.37426 -9.03725  -3.63758  1.000 16.37228 ? 311  PHE A O   1 
ATOM   2088 C  CB  . PHE A  1 280 ? 32.11740 -10.65780 -1.37995  1.000 16.41912 ? 311  PHE A CB  1 
ATOM   2089 C  CG  . PHE A  1 280 ? 31.01871 -9.67535  -1.08709  1.000 16.41989 ? 311  PHE A CG  1 
ATOM   2090 C  CD1 . PHE A  1 280 ? 29.70262 -10.10417 -1.01929  1.000 17.67552 ? 311  PHE A CD1 1 
ATOM   2091 C  CD2 . PHE A  1 280 ? 31.30314 -8.32989  -0.88721  1.000 16.77760 ? 311  PHE A CD2 1 
ATOM   2092 C  CE1 . PHE A  1 280 ? 28.68946 -9.20979  -0.75515  1.000 17.22022 ? 311  PHE A CE1 1 
ATOM   2093 C  CE2 . PHE A  1 280 ? 30.29870 -7.43686  -0.62752  1.000 17.74972 ? 311  PHE A CE2 1 
ATOM   2094 C  CZ  . PHE A  1 280 ? 28.98885 -7.87849  -0.56094  1.000 16.15921 ? 311  PHE A CZ  1 
ATOM   2095 N  N   . LEU A  1 281 ? 31.26574 -9.35527  -4.37758  1.000 16.15942 ? 312  LEU A N   1 
ATOM   2096 C  CA  . LEU A  1 281 ? 31.22533 -8.06676  -5.07023  1.000 15.67844 ? 312  LEU A CA  1 
ATOM   2097 C  C   . LEU A  1 281 ? 29.77727 -7.69563  -5.37083  1.000 15.34815 ? 312  LEU A C   1 
ATOM   2098 O  O   . LEU A  1 281 ? 28.84319 -8.45424  -5.09589  1.000 15.22760 ? 312  LEU A O   1 
ATOM   2099 C  CB  . LEU A  1 281 ? 32.05079 -8.07421  -6.37042  1.000 15.81033 ? 312  LEU A CB  1 
ATOM   2100 C  CG  . LEU A  1 281 ? 31.48492 -8.85219  -7.56728  1.000 17.31453 ? 312  LEU A CG  1 
ATOM   2101 C  CD1 . LEU A  1 281 ? 32.18665 -8.47377  -8.86862  1.000 16.96778 ? 312  LEU A CD1 1 
ATOM   2102 C  CD2 . LEU A  1 281 ? 31.60297 -10.35979 -7.37594  1.000 18.46641 ? 312  LEU A CD2 1 
ATOM   2103 N  N   . SER A  1 282 ? 29.60345 -6.49880  -5.92447  1.000 15.34095 ? 313  SER A N   1 
ATOM   2104 C  CA  . SER A  1 282 ? 28.32529 -6.04601  -6.45187  1.000 14.34310 ? 313  SER A CA  1 
ATOM   2105 C  C   . SER A  1 282 ? 28.36714 -6.08018  -7.97602  1.000 16.35136 ? 313  SER A C   1 
ATOM   2106 O  O   . SER A  1 282 ? 29.43636 -5.95050  -8.57943  1.000 15.80690 ? 313  SER A O   1 
ATOM   2107 C  CB  . SER A  1 282 ? 28.01253 -4.62767  -5.96719  1.000 15.79139 ? 313  SER A CB  1 
ATOM   2108 O  OG  . SER A  1 282 ? 26.73962 -4.21654  -6.44887  1.000 15.04447 ? 313  SER A OG  1 
ATOM   2109 N  N   . ASP A  1 283 ? 27.20620 -6.25519  -8.60858  1.000 16.09486 ? 314  ASP A N   1 
ATOM   2110 C  CA  . ASP A  1 283 ? 27.20684 -6.24307  -10.07020 1.000 16.17437 ? 314  ASP A CA  1 
ATOM   2111 C  C   . ASP A  1 283 ? 27.30866 -4.83483  -10.65656 1.000 16.04783 ? 314  ASP A C   1 
ATOM   2112 O  O   . ASP A  1 283 ? 27.63377 -4.69848  -11.84334 1.000 15.41500 ? 314  ASP A O   1 
ATOM   2113 C  CB  . ASP A  1 283 ? 25.96434 -6.95780  -10.62807 1.000 17.02324 ? 314  ASP A CB  1 
ATOM   2114 C  CG  . ASP A  1 283 ? 24.66650 -6.19114  -10.40338 1.000 16.84899 ? 314  ASP A CG  1 
ATOM   2115 O  OD1 . ASP A  1 283 ? 24.56394 -5.35735  -9.48762  1.000 17.14978 ? 314  ASP A OD1 1 
ATOM   2116 O  OD2 . ASP A  1 283 ? 23.71242 -6.43217  -11.16940 1.000 17.98077 ? 314  ASP A OD2 1 
ATOM   2117 N  N   . ASN A  1 284 ? 27.04794 -3.79162  -9.87123  1.000 14.58304 ? 315  ASN A N   1 
ATOM   2118 C  CA  . ASN A  1 284 ? 27.18655 -2.41103  -10.33533 1.000 14.24386 ? 315  ASN A CA  1 
ATOM   2119 C  C   . ASN A  1 284 ? 27.02683 -1.50517  -9.11853  1.000 15.21022 ? 315  ASN A C   1 
ATOM   2120 O  O   . ASN A  1 284 ? 26.81136 -1.97797  -7.99658  1.000 14.58784 ? 315  ASN A O   1 
ATOM   2121 C  CB  . ASN A  1 284 ? 26.18265 -2.06398  -11.45165 1.000 15.60384 ? 315  ASN A CB  1 
ATOM   2122 C  CG  . ASN A  1 284 ? 24.73215 -2.37780  -11.07265 1.000 17.35163 ? 315  ASN A CG  1 
ATOM   2123 O  OD1 . ASN A  1 284 ? 24.10151 -3.26959  -11.65473 1.000 16.50268 ? 315  ASN A OD1 1 
ATOM   2124 N  ND2 . ASN A  1 284 ? 24.18917 -1.63224  -10.10537 1.000 15.56580 ? 315  ASN A ND2 1 
ATOM   2125 N  N   . GLY A  1 285 ? 27.14388 -0.20349  -9.34916  1.000 14.94967 ? 316  GLY A N   1 
ATOM   2126 C  CA  . GLY A  1 285 ? 27.05122 0.75656   -8.26108  1.000 13.79163 ? 316  GLY A CA  1 
ATOM   2127 C  C   . GLY A  1 285 ? 25.65503 0.81681   -7.66209  1.000 15.61067 ? 316  GLY A C   1 
ATOM   2128 O  O   . GLY A  1 285 ? 24.66750 0.36613   -8.23887  1.000 16.60530 ? 316  GLY A O   1 
ATOM   2129 N  N   . GLY A  1 286 ? 25.56984 1.37584   -6.46038  1.000 16.03272 ? 317  GLY A N   1 
ATOM   2130 C  CA  . GLY A  1 286 ? 24.27052 1.55826   -5.83701  1.000 14.69988 ? 317  GLY A CA  1 
ATOM   2131 C  C   . GLY A  1 286 ? 23.43437 2.59795   -6.55964  1.000 13.42698 ? 317  GLY A C   1 
ATOM   2132 O  O   . GLY A  1 286 ? 23.94520 3.56103   -7.13532  1.000 14.87833 ? 317  GLY A O   1 
ATOM   2133 N  N   . ASN A  1 287 ? 22.11647 2.40322   -6.50830  1.000 14.47522 ? 318  ASN A N   1 
ATOM   2134 C  CA  . ASN A  1 287 ? 21.16607 3.37929   -7.02784  1.000 14.99804 ? 318  ASN A CA  1 
ATOM   2135 C  C   . ASN A  1 287 ? 20.80579 4.31357   -5.87807  1.000 15.21890 ? 318  ASN A C   1 
ATOM   2136 O  O   . ASN A  1 287 ? 20.07539 3.91703   -4.95936  1.000 15.75282 ? 318  ASN A O   1 
ATOM   2137 C  CB  . ASN A  1 287 ? 19.92990 2.67473   -7.59224  1.000 15.92578 ? 318  ASN A CB  1 
ATOM   2138 C  CG  . ASN A  1 287 ? 18.95573 3.64517   -8.25433  1.000 16.83990 ? 318  ASN A CG  1 
ATOM   2139 O  OD1 . ASN A  1 287 ? 18.91235 4.82829   -7.92714  1.000 17.91133 ? 318  ASN A OD1 1 
ATOM   2140 N  ND2 . ASN A  1 287 ? 18.17667 3.13488   -9.21218  1.000 18.57716 ? 318  ASN A ND2 1 
ATOM   2141 N  N   . PHE A  1 288 ? 21.32755 5.54491   -5.90541  1.000 14.99132 ? 319  PHE A N   1 
ATOM   2142 C  CA  . PHE A  1 288 ? 21.09849 6.39947   -4.74167  1.000 17.16354 ? 319  PHE A CA  1 
ATOM   2143 C  C   . PHE A  1 288 ? 19.68291 6.97737   -4.68694  1.000 16.61619 ? 319  PHE A C   1 
ATOM   2144 O  O   . PHE A  1 288 ? 19.36826 7.70587   -3.74398  1.000 19.65043 ? 319  PHE A O   1 
ATOM   2145 C  CB  . PHE A  1 288 ? 22.19812 7.48822   -4.60974  1.000 18.08232 ? 319  PHE A CB  1 
ATOM   2146 C  CG  . PHE A  1 288 ? 22.37471 8.43543   -5.78895  1.000 16.89452 ? 319  PHE A CG  1 
ATOM   2147 C  CD1 . PHE A  1 288 ? 21.35804 8.71017   -6.69261  1.000 17.07807 ? 319  PHE A CD1 1 
ATOM   2148 C  CD2 . PHE A  1 288 ? 23.59309 9.10417   -5.94092  1.000 19.38142 ? 319  PHE A CD2 1 
ATOM   2149 C  CE1 . PHE A  1 288 ? 21.55786 9.61460   -7.73851  1.000 17.80296 ? 319  PHE A CE1 1 
ATOM   2150 C  CE2 . PHE A  1 288 ? 23.80274 10.01413  -6.98684  1.000 17.34354 ? 319  PHE A CE2 1 
ATOM   2151 C  CZ  . PHE A  1 288 ? 22.78201 10.26654  -7.88580  1.000 19.51108 ? 319  PHE A CZ  1 
ATOM   2152 N  N   . ASN A  1 289 ? 18.79657 6.60667   -5.61713  1.000 16.37329 ? 320  ASN A N   1 
ATOM   2153 C  CA  . ASN A  1 289 ? 17.37928 6.91326   -5.45235  1.000 17.43691 ? 320  ASN A CA  1 
ATOM   2154 C  C   . ASN A  1 289 ? 16.65415 5.90034   -4.57777  1.000 18.82461 ? 320  ASN A C   1 
ATOM   2155 O  O   . ASN A  1 289 ? 15.53598 6.17898   -4.13086  1.000 18.30787 ? 320  ASN A O   1 
ATOM   2156 C  CB  . ASN A  1 289 ? 16.67553 6.95914   -6.80557  1.000 18.26154 ? 320  ASN A CB  1 
ATOM   2157 C  CG  . ASN A  1 289 ? 17.17658 8.06938   -7.66317  1.000 19.42093 ? 320  ASN A CG  1 
ATOM   2158 O  OD1 . ASN A  1 289 ? 17.40531 9.16300   -7.17966  1.000 19.79156 ? 320  ASN A OD1 1 
ATOM   2159 N  ND2 . ASN A  1 289 ? 17.36088 7.79643   -8.94917  1.000 27.12313 ? 320  ASN A ND2 1 
ATOM   2160 N  N   . HIS A  1 290 ? 17.24639 4.73303   -4.34119  1.000 17.26667 ? 321  HIS A N   1 
ATOM   2161 C  CA  . HIS A  1 290 ? 16.56443 3.64777   -3.64093  1.000 17.65728 ? 321  HIS A CA  1 
ATOM   2162 C  C   . HIS A  1 290 ? 17.44450 3.07513   -2.55309  1.000 17.31332 ? 321  HIS A C   1 
ATOM   2163 O  O   . HIS A  1 290 ? 17.66031 1.85896   -2.47467  1.000 18.67727 ? 321  HIS A O   1 
ATOM   2164 C  CB  . HIS A  1 290 ? 16.14565 2.56397   -4.62019  1.000 20.61533 ? 321  HIS A CB  1 
ATOM   2165 C  CG  . HIS A  1 290 ? 15.21209 3.05552   -5.67178  1.000 22.17495 ? 321  HIS A CG  1 
ATOM   2166 N  ND1 . HIS A  1 290 ? 13.91544 3.42561   -5.39188  1.000 23.02044 ? 321  HIS A ND1 1 
ATOM   2167 C  CD2 . HIS A  1 290 ? 15.39316 3.27771   -6.99500  1.000 22.98616 ? 321  HIS A CD2 1 
ATOM   2168 C  CE1 . HIS A  1 290 ? 13.33073 3.83958   -6.50266  1.000 27.66314 ? 321  HIS A CE1 1 
ATOM   2169 N  NE2 . HIS A  1 290 ? 14.20777 3.76510   -7.48804  1.000 26.47530 ? 321  HIS A NE2 1 
ATOM   2170 N  N   . GLY A  1 291 ? 17.97388 3.97009   -1.70439  1.000 19.18816 ? 322  GLY A N   1 
ATOM   2171 C  CA  . GLY A  1 291 ? 18.56276 3.60532   -0.43662  1.000 20.08905 ? 322  GLY A CA  1 
ATOM   2172 C  C   . GLY A  1 291 ? 20.07701 3.52707   -0.41224  1.000 18.48127 ? 322  GLY A C   1 
ATOM   2173 O  O   . GLY A  1 291 ? 20.65762 3.51692   0.67596   1.000 19.08942 ? 322  GLY A O   1 
ATOM   2174 N  N   . ALA A  1 292 ? 20.73018 3.46285   -1.56742  1.000 17.36598 ? 323  ALA A N   1 
ATOM   2175 C  CA  . ALA A  1 292 ? 22.15586 3.16872   -1.62089  1.000 15.86214 ? 323  ALA A CA  1 
ATOM   2176 C  C   . ALA A  1 292 ? 22.99961 4.42636   -1.42607  1.000 16.02839 ? 323  ALA A C   1 
ATOM   2177 O  O   . ALA A  1 292 ? 22.54443 5.55110   -1.63038  1.000 16.66508 ? 323  ALA A O   1 
ATOM   2178 C  CB  . ALA A  1 292 ? 22.50625 2.51210   -2.95839  1.000 15.84208 ? 323  ALA A CB  1 
ATOM   2179 N  N   . ASN A  1 293 ? 24.25391 4.21409   -1.02845  1.000 14.41294 ? 324  ASN A N   1 
ATOM   2180 C  CA  . ASN A  1 293 ? 25.20527 5.29574   -0.78797  1.000 15.47070 ? 324  ASN A CA  1 
ATOM   2181 C  C   . ASN A  1 293 ? 26.52957 4.87082   -1.40926  1.000 15.87000 ? 324  ASN A C   1 
ATOM   2182 O  O   . ASN A  1 293 ? 27.06226 3.81691   -1.05784  1.000 15.97989 ? 324  ASN A O   1 
ATOM   2183 C  CB  . ASN A  1 293 ? 25.34771 5.55401   0.72391   1.000 17.75050 ? 324  ASN A CB  1 
ATOM   2184 C  CG  . ASN A  1 293 ? 26.18964 6.77177   1.04475   1.000 24.45505 ? 324  ASN A CG  1 
ATOM   2185 O  OD1 . ASN A  1 293 ? 27.07614 7.14577   0.29322   1.000 21.78236 ? 324  ASN A OD1 1 
ATOM   2186 N  ND2 . ASN A  1 293 ? 25.90665 7.40158   2.18020   1.000 29.99595 ? 324  ASN A ND2 1 
ATOM   2187 N  N   . ASN A  1 294 ? 27.04131 5.65608   -2.36605  1.000 14.89305 ? 325  ASN A N   1 
ATOM   2188 C  CA  . ASN A  1 294 ? 28.27623 5.30598   -3.05891  1.000 15.33232 ? 325  ASN A CA  1 
ATOM   2189 C  C   . ASN A  1 294 ? 29.47930 6.11533   -2.58092  1.000 17.34680 ? 325  ASN A C   1 
ATOM   2190 O  O   . ASN A  1 294 ? 30.50984 6.14018   -3.26102  1.000 16.69125 ? 325  ASN A O   1 
ATOM   2191 C  CB  . ASN A  1 294 ? 28.09012 5.47531   -4.57039  1.000 16.43080 ? 325  ASN A CB  1 
ATOM   2192 C  CG  . ASN A  1 294 ? 27.06812 4.51739   -5.13296  1.000 15.24501 ? 325  ASN A CG  1 
ATOM   2193 O  OD1 . ASN A  1 294 ? 27.02026 3.34568   -4.74961  1.000 14.54263 ? 325  ASN A OD1 1 
ATOM   2194 N  ND2 . ASN A  1 294 ? 26.22138 5.01550   -6.04023  1.000 14.15960 ? 325  ASN A ND2 1 
ATOM   2195 N  N   . TYR A  1 295 ? 29.37653 6.75938   -1.42211  1.000 15.64886 ? 326  TYR A N   1 
ATOM   2196 C  CA  . TYR A  1 295 ? 30.46660 7.60139   -0.94396  1.000 16.85793 ? 326  TYR A CA  1 
ATOM   2197 C  C   . TYR A  1 295 ? 31.77984 6.81336   -0.93655  1.000 15.75229 ? 326  TYR A C   1 
ATOM   2198 O  O   . TYR A  1 295 ? 31.79719 5.63983   -0.54166  1.000 17.44795 ? 326  TYR A O   1 
ATOM   2199 C  CB  . TYR A  1 295 ? 30.13232 8.10734   0.46555   1.000 16.77587 ? 326  TYR A CB  1 
ATOM   2200 C  CG  . TYR A  1 295 ? 31.18945 9.00541   1.06249   1.000 18.72712 ? 326  TYR A CG  1 
ATOM   2201 C  CD1 . TYR A  1 295 ? 32.24368 8.47479   1.80395   1.000 19.03761 ? 326  TYR A CD1 1 
ATOM   2202 C  CD2 . TYR A  1 295 ? 31.14206 10.37586  0.86291   1.000 21.49018 ? 326  TYR A CD2 1 
ATOM   2203 C  CE1 . TYR A  1 295 ? 33.22500 9.30057   2.33348   1.000 22.44391 ? 326  TYR A CE1 1 
ATOM   2204 C  CE2 . TYR A  1 295 ? 32.10955 11.20763  1.39319   1.000 24.81002 ? 326  TYR A CE2 1 
ATOM   2205 C  CZ  . TYR A  1 295 ? 33.14460 10.66103  2.11946   1.000 25.08066 ? 326  TYR A CZ  1 
ATOM   2206 O  OH  . TYR A  1 295 ? 34.11304 11.49641  2.64121   1.000 33.13113 ? 326  TYR A OH  1 
ATOM   2207 N  N   . PRO A  1 296 ? 32.91251 7.42518   -1.34126  1.000 16.26727 ? 327  PRO A N   1 
ATOM   2208 C  CA  . PRO A  1 296 ? 33.12028 8.82313   -1.74678  1.000 17.94716 ? 327  PRO A CA  1 
ATOM   2209 C  C   . PRO A  1 296 ? 33.03600 9.05614   -3.25097  1.000 15.66220 ? 327  PRO A C   1 
ATOM   2210 O  O   . PRO A  1 296 ? 33.50961 10.08948  -3.74438  1.000 17.09074 ? 327  PRO A O   1 
ATOM   2211 C  CB  . PRO A  1 296 ? 34.53650 9.09781   -1.23285  1.000 16.86771 ? 327  PRO A CB  1 
ATOM   2212 C  CG  . PRO A  1 296 ? 35.24317 7.78231   -1.51082  1.000 17.78738 ? 327  PRO A CG  1 
ATOM   2213 C  CD  . PRO A  1 296 ? 34.19994 6.72269   -1.17159  1.000 18.78055 ? 327  PRO A CD  1 
ATOM   2214 N  N   . LEU A  1 297 ? 32.41520 8.12772   -3.97925  1.000 15.88394 ? 328  LEU A N   1 
ATOM   2215 C  CA  . LEU A  1 297 ? 32.32197 8.20497   -5.43218  1.000 14.58054 ? 328  LEU A CA  1 
ATOM   2216 C  C   . LEU A  1 297 ? 31.18468 9.11425   -5.87042  1.000 17.51298 ? 328  LEU A C   1 
ATOM   2217 O  O   . LEU A  1 297 ? 30.15551 9.23886   -5.19922  1.000 18.52578 ? 328  LEU A O   1 
ATOM   2218 C  CB  . LEU A  1 297 ? 32.09732 6.81837   -6.03677  1.000 15.16336 ? 328  LEU A CB  1 
ATOM   2219 C  CG  . LEU A  1 297 ? 32.96836 5.68889   -5.49259  1.000 15.45234 ? 328  LEU A CG  1 
ATOM   2220 C  CD1 . LEU A  1 297 ? 32.64743 4.37609   -6.20909  1.000 15.33565 ? 328  LEU A CD1 1 
ATOM   2221 C  CD2 . LEU A  1 297 ? 34.45713 6.03745   -5.63925  1.000 16.52427 ? 328  LEU A CD2 1 
ATOM   2222 N  N   . LYS A  1 298 ? 31.38239 9.75076   -7.01987  1.000 15.09113 ? 329  LYS A N   1 
ATOM   2223 C  CA  . LYS A  1 298 ? 30.32606 10.51119  -7.66620  1.000 15.61358 ? 329  LYS A CA  1 
ATOM   2224 C  C   . LYS A  1 298 ? 29.37202 9.56685   -8.38523  1.000 17.27828 ? 329  LYS A C   1 
ATOM   2225 O  O   . LYS A  1 298 ? 29.78572 8.55162   -8.95644  1.000 15.29493 ? 329  LYS A O   1 
ATOM   2226 C  CB  . LYS A  1 298 ? 30.93367 11.50601  -8.66558  1.000 16.58028 ? 329  LYS A CB  1 
ATOM   2227 C  CG  . LYS A  1 298 ? 29.92922 12.34244  -9.45998  1.000 15.82155 ? 329  LYS A CG  1 
ATOM   2228 C  CD  . LYS A  1 298 ? 30.62754 13.34717  -10.38342 1.000 18.43861 ? 329  LYS A CD  1 
ATOM   2229 C  CE  . LYS A  1 298 ? 31.23886 14.50612  -9.63291  1.000 20.59964 ? 329  LYS A CE  1 
ATOM   2230 N  NZ  . LYS A  1 298 ? 31.84684 15.47250  -10.61147 1.000 19.66231 ? 329  LYS A NZ  1 
ATOM   2231 N  N   . GLY A  1 299 ? 28.09538 9.90766   -8.36060  1.000 15.89559 ? 330  GLY A N   1 
ATOM   2232 C  CA  . GLY A  1 299 ? 27.15861 9.24800   -9.24613  1.000 15.29864 ? 330  GLY A CA  1 
ATOM   2233 C  C   . GLY A  1 299 ? 26.49568 8.01043   -8.67876  1.000 16.51616 ? 330  GLY A C   1 
ATOM   2234 O  O   . GLY A  1 299 ? 26.55188 7.68276   -7.48553  1.000 15.15654 ? 330  GLY A O   1 
ATOM   2235 N  N   . THR A  1 300 ? 25.85061 7.29770   -9.60099  1.000 15.12237 ? 331  THR A N   1 
ATOM   2236 C  CA  . THR A  1 300 ? 24.85916 6.29668   -9.25321  1.000 15.37922 ? 331  THR A CA  1 
ATOM   2237 C  C   . THR A  1 300 ? 24.88705 5.20079   -10.31013 1.000 17.74006 ? 331  THR A C   1 
ATOM   2238 O  O   . THR A  1 300 ? 25.47785 5.36039   -11.38520 1.000 15.32506 ? 331  THR A O   1 
ATOM   2239 C  CB  . THR A  1 300 ? 23.47441 6.95585   -9.13078  1.000 14.25805 ? 331  THR A CB  1 
ATOM   2240 O  OG1 . THR A  1 300 ? 22.50891 6.00925   -8.66758  1.000 14.87175 ? 331  THR A OG1 1 
ATOM   2241 C  CG2 . THR A  1 300 ? 23.02015 7.51797   -10.48509 1.000 17.91763 ? 331  THR A CG2 1 
ATOM   2242 N  N   . LYS A  1 301 ? 24.24644 4.07977   -9.98251  1.000 15.23893 ? 332  LYS A N   1 
ATOM   2243 C  CA  . LYS A  1 301 ? 24.01717 2.98613   -10.92380 1.000 14.83211 ? 332  LYS A CA  1 
ATOM   2244 C  C   . LYS A  1 301 ? 23.73028 3.51551   -12.32819 1.000 14.47982 ? 332  LYS A C   1 
ATOM   2245 O  O   . LYS A  1 301 ? 22.89237 4.40401   -12.51558 1.000 15.78674 ? 332  LYS A O   1 
ATOM   2246 C  CB  . LYS A  1 301 ? 22.83016 2.15483   -10.42723 1.000 15.33176 ? 332  LYS A CB  1 
ATOM   2247 C  CG  . LYS A  1 301 ? 22.33877 1.10235   -11.42605 1.000 14.80869 ? 332  LYS A CG  1 
ATOM   2248 C  CD  . LYS A  1 301 ? 21.09182 0.41321   -10.87619 1.000 16.42381 ? 332  LYS A CD  1 
ATOM   2249 C  CE  . LYS A  1 301 ? 20.58542 -0.67405  -11.81997 1.000 17.43848 ? 332  LYS A CE  1 
ATOM   2250 N  NZ  . LYS A  1 301 ? 19.28744 -1.25310  -11.30184 1.000 20.93324 ? 332  LYS A NZ  1 
ATOM   2251 N  N   . GLY A  1 302 ? 24.43862 2.95944   -13.31647 1.000 14.18441 ? 333  GLY A N   1 
ATOM   2252 C  CA  . GLY A  1 302 ? 24.23902 3.32219   -14.70040 1.000 14.76074 ? 333  GLY A CA  1 
ATOM   2253 C  C   . GLY A  1 302 ? 25.17239 4.39710   -15.22177 1.000 16.56003 ? 333  GLY A C   1 
ATOM   2254 O  O   . GLY A  1 302 ? 25.29995 4.54536   -16.44472 1.000 16.25966 ? 333  GLY A O   1 
ATOM   2255 N  N   . ASP A  1 303 ? 25.82949 5.14609   -14.33726 1.000 14.71031 ? 334  ASP A N   1 
ATOM   2256 C  CA  . ASP A  1 303 ? 26.77998 6.18796   -14.72593 1.000 15.49570 ? 334  ASP A CA  1 
ATOM   2257 C  C   . ASP A  1 303 ? 28.14506 5.59931   -15.08086 1.000 14.30535 ? 334  ASP A C   1 
ATOM   2258 O  O   . ASP A  1 303 ? 28.49993 4.48767   -14.67855 1.000 15.36460 ? 334  ASP A O   1 
ATOM   2259 C  CB  . ASP A  1 303 ? 27.00077 7.19459   -13.58863 1.000 16.09692 ? 334  ASP A CB  1 
ATOM   2260 C  CG  . ASP A  1 303 ? 25.77206 8.01534   -13.25417 1.000 15.98344 ? 334  ASP A CG  1 
ATOM   2261 O  OD1 . ASP A  1 303 ? 24.78529 8.01548   -14.01522 1.000 16.87828 ? 334  ASP A OD1 1 
ATOM   2262 O  OD2 . ASP A  1 303 ? 25.81922 8.68205   -12.20065 1.000 16.42099 ? 334  ASP A OD2 1 
ATOM   2263 N  N   . THR A  1 304 ? 28.94351 6.39367   -15.81182 1.000 14.77098 ? 335  THR A N   1 
ATOM   2264 C  CA  . THR A  1 304 ? 30.36144 6.09366   -15.96893 1.000 14.50110 ? 335  THR A CA  1 
ATOM   2265 C  C   . THR A  1 304 ? 31.24351 6.97010   -15.09391 1.000 16.95536 ? 335  THR A C   1 
ATOM   2266 O  O   . THR A  1 304 ? 32.46956 6.87646   -15.19017 1.000 16.71345 ? 335  THR A O   1 
ATOM   2267 C  CB  . THR A  1 304 ? 30.80654 6.22203   -17.42131 1.000 15.34343 ? 335  THR A CB  1 
ATOM   2268 O  OG1 . THR A  1 304 ? 30.50376 7.53275   -17.89814 1.000 14.48907 ? 335  THR A OG1 1 
ATOM   2269 C  CG2 . THR A  1 304 ? 30.13539 5.13959   -18.30062 1.000 17.33823 ? 335  THR A CG2 1 
ATOM   2270 N  N   . TRP A  1 305 ? 30.65232 7.80855   -14.24330 1.000 15.36038 ? 336  TRP A N   1 
ATOM   2271 C  CA  . TRP A  1 305 ? 31.35385 8.17494   -13.02137 1.000 14.73353 ? 336  TRP A CA  1 
ATOM   2272 C  C   . TRP A  1 305 ? 31.71697 6.90249   -12.26360 1.000 16.39964 ? 336  TRP A C   1 
ATOM   2273 O  O   . TRP A  1 305 ? 31.11645 5.84502   -12.46400 1.000 16.34911 ? 336  TRP A O   1 
ATOM   2274 C  CB  . TRP A  1 305 ? 30.47447 9.01699   -12.11116 1.000 15.90421 ? 336  TRP A CB  1 
ATOM   2275 C  CG  . TRP A  1 305 ? 29.91018 10.26371  -12.67093 1.000 15.24401 ? 336  TRP A CG  1 
ATOM   2276 C  CD1 . TRP A  1 305 ? 28.58083 10.56587  -12.80567 1.000 15.22386 ? 336  TRP A CD1 1 
ATOM   2277 C  CD2 . TRP A  1 305 ? 30.63515 11.42008  -13.10616 1.000 14.98585 ? 336  TRP A CD2 1 
ATOM   2278 N  NE1 . TRP A  1 305 ? 28.43562 11.83592  -13.31115 1.000 15.37573 ? 336  TRP A NE1 1 
ATOM   2279 C  CE2 . TRP A  1 305 ? 29.67932 12.37749  -13.51946 1.000 16.17491 ? 336  TRP A CE2 1 
ATOM   2280 C  CE3 . TRP A  1 305 ? 32.00023 11.73529  -13.20466 1.000 15.56228 ? 336  TRP A CE3 1 
ATOM   2281 C  CZ2 . TRP A  1 305 ? 30.03928 13.63862  -14.01047 1.000 16.74994 ? 336  TRP A CZ2 1 
ATOM   2282 C  CZ3 . TRP A  1 305 ? 32.36155 12.99817  -13.69868 1.000 16.48852 ? 336  TRP A CZ3 1 
ATOM   2283 C  CH2 . TRP A  1 305 ? 31.37855 13.92952  -14.09630 1.000 15.78758 ? 336  TRP A CH2 1 
ATOM   2284 N  N   . GLU A  1 306 ? 32.69892 7.01207   -11.36046 1.000 14.83699 ? 337  GLU A N   1 
ATOM   2285 C  CA  . GLU A  1 306 ? 33.10092 5.84611   -10.57499 1.000 16.94167 ? 337  GLU A CA  1 
ATOM   2286 C  C   . GLU A  1 306 ? 31.90960 5.18117   -9.90037  1.000 15.70080 ? 337  GLU A C   1 
ATOM   2287 O  O   . GLU A  1 306 ? 31.87639 3.95736   -9.75357  1.000 15.79811 ? 337  GLU A O   1 
ATOM   2288 C  CB  . GLU A  1 306 ? 34.12057 6.23438   -9.50339  1.000 14.81885 ? 337  GLU A CB  1 
ATOM   2289 C  CG  . GLU A  1 306 ? 35.46249 6.73857   -10.05881 1.000 14.27323 ? 337  GLU A CG  1 
ATOM   2290 C  CD  . GLU A  1 306 ? 36.25494 5.63023   -10.74469 1.000 16.21044 ? 337  GLU A CD  1 
ATOM   2291 O  OE1 . GLU A  1 306 ? 36.00624 5.37059   -11.93863 1.000 18.35603 ? 337  GLU A OE1 1 
ATOM   2292 O  OE2 . GLU A  1 306 ? 37.10482 4.98817   -10.08713 1.000 17.36431 ? 337  GLU A OE2 1 
ATOM   2293 N  N   . GLY A  1 307 ? 30.93613 5.97901   -9.45129  1.000 14.99978 ? 338  GLY A N   1 
ATOM   2294 C  CA  . GLY A  1 307 ? 29.82973 5.42453   -8.68318  1.000 16.63919 ? 338  GLY A CA  1 
ATOM   2295 C  C   . GLY A  1 307 ? 28.99485 4.41381   -9.43918  1.000 15.27950 ? 338  GLY A C   1 
ATOM   2296 O  O   . GLY A  1 307 ? 28.27047 3.63225   -8.81650  1.000 15.21101 ? 338  GLY A O   1 
ATOM   2297 N  N   . GLY A  1 308 ? 29.07097 4.41440   -10.77106 1.000 14.75966 ? 339  GLY A N   1 
ATOM   2298 C  CA  . GLY A  1 308 ? 28.27098 3.47644   -11.53674 1.000 14.34737 ? 339  GLY A CA  1 
ATOM   2299 C  C   . GLY A  1 308 ? 28.84278 2.07651   -11.60866 1.000 13.69898 ? 339  GLY A C   1 
ATOM   2300 O  O   . GLY A  1 308 ? 28.08345 1.10426   -11.70213 1.000 14.46889 ? 339  GLY A O   1 
ATOM   2301 N  N   . TYR A  1 309 ? 30.17514 1.94078   -11.57235 1.000 15.97495 ? 340  TYR A N   1 
ATOM   2302 C  CA  . TYR A  1 309 ? 30.76066 0.63372   -11.86007 1.000 15.01733 ? 340  TYR A CA  1 
ATOM   2303 C  C   . TYR A  1 309 ? 32.01479 0.31233   -11.05285 1.000 14.78612 ? 340  TYR A C   1 
ATOM   2304 O  O   . TYR A  1 309 ? 32.64551 -0.72305  -11.31487 1.000 15.36569 ? 340  TYR A O   1 
ATOM   2305 C  CB  . TYR A  1 309 ? 31.05335 0.49724   -13.38386 1.000 16.30881 ? 340  TYR A CB  1 
ATOM   2306 C  CG  . TYR A  1 309 ? 32.12143 1.42235   -13.96827 1.000 14.77043 ? 340  TYR A CG  1 
ATOM   2307 C  CD1 . TYR A  1 309 ? 31.85885 2.76865   -14.18985 1.000 15.72601 ? 340  TYR A CD1 1 
ATOM   2308 C  CD2 . TYR A  1 309 ? 33.36676 0.91951   -14.34321 1.000 15.63890 ? 340  TYR A CD2 1 
ATOM   2309 C  CE1 . TYR A  1 309 ? 32.82398 3.61098   -14.74235 1.000 16.11732 ? 340  TYR A CE1 1 
ATOM   2310 C  CE2 . TYR A  1 309 ? 34.34385 1.74568   -14.88572 1.000 16.61148 ? 340  TYR A CE2 1 
ATOM   2311 C  CZ  . TYR A  1 309 ? 34.05787 3.08018   -15.09945 1.000 16.50128 ? 340  TYR A CZ  1 
ATOM   2312 O  OH  . TYR A  1 309 ? 35.01776 3.91184   -15.65018 1.000 17.84453 ? 340  TYR A OH  1 
ATOM   2313 N  N   . ARG A  1 310 ? 32.38482 1.12758   -10.07411 1.000 14.14848 ? 341  ARG A N   1 
ATOM   2314 C  CA  . ARG A  1 310 ? 33.38559 0.73697   -9.08900  1.000 13.99808 ? 341  ARG A CA  1 
ATOM   2315 C  C   . ARG A  1 310 ? 32.64029 0.17019   -7.88461  1.000 13.71711 ? 341  ARG A C   1 
ATOM   2316 O  O   . ARG A  1 310 ? 31.69938 0.80385   -7.39149  1.000 16.98701 ? 341  ARG A O   1 
ATOM   2317 C  CB  . ARG A  1 310 ? 34.22645 1.94424   -8.70368  1.000 15.21786 ? 341  ARG A CB  1 
ATOM   2318 C  CG  . ARG A  1 310 ? 35.39850 1.66256   -7.78790  1.000 14.79215 ? 341  ARG A CG  1 
ATOM   2319 C  CD  . ARG A  1 310 ? 36.23326 2.92815   -7.72116  1.000 14.87860 ? 341  ARG A CD  1 
ATOM   2320 N  NE  . ARG A  1 310 ? 37.29805 2.85787   -6.73144  1.000 16.08776 ? 341  ARG A NE  1 
ATOM   2321 C  CZ  . ARG A  1 310 ? 38.29145 3.73554   -6.66646  1.000 16.94198 ? 341  ARG A CZ  1 
ATOM   2322 N  NH1 . ARG A  1 310 ? 38.42547 4.69284   -7.56964  1.000 17.19915 ? 341  ARG A NH1 1 
ATOM   2323 N  NH2 . ARG A  1 310 ? 39.16594 3.65368   -5.66648  1.000 17.75076 ? 341  ARG A NH2 1 
ATOM   2324 N  N   . VAL A  1 311 ? 33.02558 -1.02548  -7.44262  1.000 14.41252 ? 342  VAL A N   1 
ATOM   2325 C  CA  . VAL A  1 311 ? 32.19479 -1.77874  -6.49742  1.000 13.83790 ? 342  VAL A CA  1 
ATOM   2326 C  C   . VAL A  1 311 ? 33.05363 -2.29511  -5.35164  1.000 16.14449 ? 342  VAL A C   1 
ATOM   2327 O  O   . VAL A  1 311 ? 34.27675 -2.44924  -5.48627  1.000 16.55839 ? 342  VAL A O   1 
ATOM   2328 C  CB  . VAL A  1 311 ? 31.46603 -2.96078  -7.18690  1.000 15.36981 ? 342  VAL A CB  1 
ATOM   2329 C  CG1 . VAL A  1 311 ? 30.52049 -2.43313  -8.26160  1.000 16.52349 ? 342  VAL A CG1 1 
ATOM   2330 C  CG2 . VAL A  1 311 ? 32.46350 -3.95935  -7.77249  1.000 15.47561 ? 342  VAL A CG2 1 
ATOM   2331 N  N   . PRO A  1 312 ? 32.43382 -2.62022  -4.21694  1.000 16.15089 ? 343  PRO A N   1 
ATOM   2332 C  CA  . PRO A  1 312 ? 33.18369 -3.30879  -3.16530  1.000 14.90002 ? 343  PRO A CA  1 
ATOM   2333 C  C   . PRO A  1 312 ? 33.57898 -4.68999  -3.65261  1.000 15.34706 ? 343  PRO A C   1 
ATOM   2334 O  O   . PRO A  1 312 ? 32.84728 -5.33020  -4.41177  1.000 16.57251 ? 343  PRO A O   1 
ATOM   2335 C  CB  . PRO A  1 312 ? 32.18225 -3.40170  -2.00489  1.000 16.36740 ? 343  PRO A CB  1 
ATOM   2336 C  CG  . PRO A  1 312 ? 31.05785 -2.40622  -2.36114  1.000 17.29938 ? 343  PRO A CG  1 
ATOM   2337 C  CD  . PRO A  1 312 ? 31.01237 -2.44150  -3.85462  1.000 16.91488 ? 343  PRO A CD  1 
ATOM   2338 N  N   . MET A  1 313 ? 34.75397 -5.15034  -3.22718  1.000 14.73916 ? 344  MET A N   1 
ATOM   2339 C  CA  . MET A  1 313 ? 35.11662 -6.53238  -3.51632  1.000 15.83929 ? 344  MET A CA  1 
ATOM   2340 C  C   . MET A  1 313 ? 36.16614 -6.99682  -2.52190  1.000 16.81995 ? 344  MET A C   1 
ATOM   2341 O  O   . MET A  1 313 ? 37.05778 -6.22748  -2.15766  1.000 17.15600 ? 344  MET A O   1 
ATOM   2342 C  CB  . MET A  1 313 ? 35.64616 -6.71138  -4.95295  1.000 17.77918 ? 344  MET A CB  1 
ATOM   2343 C  CG  . MET A  1 313 ? 35.95744 -8.18375  -5.31349  1.000 16.96837 ? 344  MET A CG  1 
ATOM   2344 S  SD  . MET A  1 313 ? 36.23567 -8.45749  -7.09389  1.000 21.24051 ? 344  MET A SD  1 
ATOM   2345 C  CE  . MET A  1 313 ? 37.90512 -7.84953  -7.25661  1.000 19.56779 ? 344  MET A CE  1 
ATOM   2346 N  N   . PHE A  1 314 ? 36.04637 -8.25196  -2.08490  1.000 15.94730 ? 345  PHE A N   1 
ATOM   2347 C  CA  . PHE A  1 314 ? 37.14947 -8.92446  -1.40745  1.000 16.75672 ? 345  PHE A CA  1 
ATOM   2348 C  C   . PHE A  1 314 ? 37.33393 -10.32802 -1.96576  1.000 17.50754 ? 345  PHE A C   1 
ATOM   2349 O  O   . PHE A  1 314 ? 36.42137 -10.91416 -2.55436  1.000 15.81619 ? 345  PHE A O   1 
ATOM   2350 C  CB  . PHE A  1 314 ? 36.98021 -8.96875  0.13934   1.000 17.35169 ? 345  PHE A CB  1 
ATOM   2351 C  CG  . PHE A  1 314 ? 35.81590 -9.81431  0.64331   1.000 16.95336 ? 345  PHE A CG  1 
ATOM   2352 C  CD1 . PHE A  1 314 ? 35.87669 -11.20766 0.64317   1.000 16.19614 ? 345  PHE A CD1 1 
ATOM   2353 C  CD2 . PHE A  1 314 ? 34.68774 -9.20265  1.18438   1.000 17.29586 ? 345  PHE A CD2 1 
ATOM   2354 C  CE1 . PHE A  1 314 ? 34.81381 -11.97307 1.12470   1.000 19.34638 ? 345  PHE A CE1 1 
ATOM   2355 C  CE2 . PHE A  1 314 ? 33.63263 -9.96131  1.68753   1.000 15.33928 ? 345  PHE A CE2 1 
ATOM   2356 C  CZ  . PHE A  1 314 ? 33.69129 -11.33771 1.66223   1.000 16.40505 ? 345  PHE A CZ  1 
ATOM   2357 N  N   . PHE A  1 315 ? 38.55654 -10.83828 -1.80059  1.000 17.47406 ? 346  PHE A N   1 
ATOM   2358 C  CA  . PHE A  1 315 ? 38.89603 -12.24527 -1.98985  1.000 20.06627 ? 346  PHE A CA  1 
ATOM   2359 C  C   . PHE A  1 315 ? 39.24630 -12.81586 -0.62286  1.000 16.80656 ? 346  PHE A C   1 
ATOM   2360 O  O   . PHE A  1 315 ? 40.07364 -12.23602 0.08778   1.000 19.39474 ? 346  PHE A O   1 
ATOM   2361 C  CB  . PHE A  1 315 ? 40.12256 -12.44749 -2.89123  1.000 16.82099 ? 346  PHE A CB  1 
ATOM   2362 C  CG  . PHE A  1 315 ? 39.90143 -12.25266 -4.37238  1.000 16.41236 ? 346  PHE A CG  1 
ATOM   2363 C  CD1 . PHE A  1 315 ? 38.79133 -11.60690 -4.88609  1.000 18.03490 ? 346  PHE A CD1 1 
ATOM   2364 C  CD2 . PHE A  1 315 ? 40.86770 -12.74077 -5.25777  1.000 20.70298 ? 346  PHE A CD2 1 
ATOM   2365 C  CE1 . PHE A  1 315 ? 38.63829 -11.42657 -6.27114  1.000 18.95715 ? 346  PHE A CE1 1 
ATOM   2366 C  CE2 . PHE A  1 315 ? 40.73375 -12.57790 -6.62379  1.000 21.42362 ? 346  PHE A CE2 1 
ATOM   2367 C  CZ  . PHE A  1 315 ? 39.61238 -11.91639 -7.13954  1.000 20.16955 ? 346  PHE A CZ  1 
ATOM   2368 N  N   . HIS A  1 316 ? 38.66230 -13.95930 -0.26696  1.000 15.42204 ? 347  HIS A N   1 
ATOM   2369 C  CA  . HIS A  1 316 ? 38.98264 -14.63617 0.98880   1.000 18.76363 ? 347  HIS A CA  1 
ATOM   2370 C  C   . HIS A  1 316 ? 39.33292 -16.08662 0.68432   1.000 17.64594 ? 347  HIS A C   1 
ATOM   2371 O  O   . HIS A  1 316 ? 38.51425 -16.82338 0.12602   1.000 18.32112 ? 347  HIS A O   1 
ATOM   2372 C  CB  . HIS A  1 316 ? 37.80621 -14.55222 1.96496   1.000 17.86118 ? 347  HIS A CB  1 
ATOM   2373 C  CG  . HIS A  1 316 ? 38.02527 -15.27682 3.25900   1.000 17.41542 ? 347  HIS A CG  1 
ATOM   2374 N  ND1 . HIS A  1 316 ? 37.73608 -16.61678 3.41985   1.000 19.14938 ? 347  HIS A ND1 1 
ATOM   2375 C  CD2 . HIS A  1 316 ? 38.47776 -14.84286 4.45980   1.000 18.04533 ? 347  HIS A CD2 1 
ATOM   2376 C  CE1 . HIS A  1 316 ? 38.02035 -16.97954 4.65979   1.000 21.51529 ? 347  HIS A CE1 1 
ATOM   2377 N  NE2 . HIS A  1 316 ? 38.46258 -15.91954 5.31493   1.000 20.13098 ? 347  HIS A NE2 1 
ATOM   2378 N  N   . TRP A  1 317 ? 40.54914 -16.49006 1.04474   1.000 17.64046 ? 348  TRP A N   1 
ATOM   2379 C  CA  . TRP A  1 317 ? 41.04562 -17.82612 0.73897   1.000 18.80563 ? 348  TRP A CA  1 
ATOM   2380 C  C   . TRP A  1 317 ? 42.16107 -18.12962 1.73025   1.000 19.10633 ? 348  TRP A C   1 
ATOM   2381 O  O   . TRP A  1 317 ? 43.32393 -17.80627 1.47036   1.000 22.40147 ? 348  TRP A O   1 
ATOM   2382 C  CB  . TRP A  1 317 ? 41.53495 -17.88699 -0.70772  1.000 18.03530 ? 348  TRP A CB  1 
ATOM   2383 C  CG  . TRP A  1 317 ? 41.96309 -19.25222 -1.20789  1.000 18.86860 ? 348  TRP A CG  1 
ATOM   2384 C  CD1 . TRP A  1 317 ? 41.68003 -20.48108 -0.65416  1.000 20.77213 ? 348  TRP A CD1 1 
ATOM   2385 C  CD2 . TRP A  1 317 ? 42.75697 -19.51136 -2.36925  1.000 22.02449 ? 348  TRP A CD2 1 
ATOM   2386 N  NE1 . TRP A  1 317 ? 42.25940 -21.47824 -1.40894  1.000 22.34820 ? 348  TRP A NE1 1 
ATOM   2387 C  CE2 . TRP A  1 317 ? 42.92185 -20.91020 -2.46387  1.000 18.84081 ? 348  TRP A CE2 1 
ATOM   2388 C  CE3 . TRP A  1 317 ? 43.34545 -18.69237 -3.34009  1.000 22.66965 ? 348  TRP A CE3 1 
ATOM   2389 C  CZ2 . TRP A  1 317 ? 43.64043 -21.50296 -3.49290  1.000 20.90833 ? 348  TRP A CZ2 1 
ATOM   2390 C  CZ3 . TRP A  1 317 ? 44.06445 -19.28282 -4.35837  1.000 22.61628 ? 348  TRP A CZ3 1 
ATOM   2391 C  CH2 . TRP A  1 317 ? 44.20675 -20.67380 -4.42582  1.000 22.22817 ? 348  TRP A CH2 1 
ATOM   2392 N  N   . PRO A  1 318 ? 41.83584 -18.71366 2.88360   1.000 19.28901 ? 349  PRO A N   1 
ATOM   2393 C  CA  . PRO A  1 318 ? 42.82941 -18.79970 3.96849   1.000 22.30150 ? 349  PRO A CA  1 
ATOM   2394 C  C   . PRO A  1 318 ? 44.08707 -19.55667 3.59618   1.000 22.64426 ? 349  PRO A C   1 
ATOM   2395 O  O   . PRO A  1 318 ? 45.15721 -19.24354 4.13319   1.000 23.20407 ? 349  PRO A O   1 
ATOM   2396 C  CB  . PRO A  1 318 ? 42.05618 -19.51126 5.08534   1.000 24.67217 ? 349  PRO A CB  1 
ATOM   2397 C  CG  . PRO A  1 318 ? 40.62239 -19.14021 4.82367   1.000 23.29737 ? 349  PRO A CG  1 
ATOM   2398 C  CD  . PRO A  1 318 ? 40.49948 -19.15192 3.32264   1.000 21.66908 ? 349  PRO A CD  1 
ATOM   2399 N  N   . LYS A  1 319 ? 43.98948 -20.53200 2.69121   1.000 20.77715 ? 350  LYS A N   1 
ATOM   2400 C  CA  . LYS A  1 319 ? 45.16183 -21.30769 2.30015   1.000 23.60039 ? 350  LYS A CA  1 
ATOM   2401 C  C   . LYS A  1 319 ? 46.24706 -20.43096 1.68487   1.000 24.95267 ? 350  LYS A C   1 
ATOM   2402 O  O   . LYS A  1 319 ? 47.43901 -20.69831 1.87719   1.000 25.90414 ? 350  LYS A O   1 
ATOM   2403 C  CB  . LYS A  1 319 ? 44.73959 -22.41206 1.32421   1.000 24.84501 ? 350  LYS A CB  1 
ATOM   2404 C  CG  . LYS A  1 319 ? 45.85249 -23.36655 0.90643   1.000 30.36774 ? 350  LYS A CG  1 
ATOM   2405 C  CD  . LYS A  1 319 ? 45.30269 -24.43800 -0.02337  1.000 32.12283 ? 350  LYS A CD  1 
ATOM   2406 C  CE  . LYS A  1 319 ? 46.40369 -25.26999 -0.66632  1.000 43.03602 ? 350  LYS A CE  1 
ATOM   2407 N  NZ  . LYS A  1 319 ? 45.82956 -26.40705 -1.45309  1.000 45.30367 ? 350  LYS A NZ  1 
ATOM   2408 N  N   . LYS A  1 320 ? 45.86789 -19.36313 0.97291   1.000 21.32992 ? 351  LYS A N   1 
ATOM   2409 C  CA  . LYS A  1 320 ? 46.83174 -18.64759 0.14427   1.000 23.73730 ? 351  LYS A CA  1 
ATOM   2410 C  C   . LYS A  1 320 ? 46.86874 -17.14497 0.40571   1.000 23.73385 ? 351  LYS A C   1 
ATOM   2411 O  O   . LYS A  1 320 ? 47.93339 -16.52661 0.30695   1.000 26.36059 ? 351  LYS A O   1 
ATOM   2412 C  CB  . LYS A  1 320 ? 46.54180 -18.89376 -1.33571  1.000 24.37400 ? 351  LYS A CB  1 
ATOM   2413 C  CG  . LYS A  1 320 ? 46.70136 -20.35339 -1.78087  1.000 30.75914 ? 351  LYS A CG  1 
ATOM   2414 C  CD  . LYS A  1 320 ? 47.98281 -20.55738 -2.55950  1.000 37.78116 ? 351  LYS A CD  1 
ATOM   2415 C  CE  . LYS A  1 320 ? 48.06177 -21.96451 -3.13155  1.000 45.75581 ? 351  LYS A CE  1 
ATOM   2416 N  NZ  . LYS A  1 320 ? 48.08883 -21.96636 -4.62824  1.000 51.09251 ? 351  LYS A NZ  1 
ATOM   2417 N  N   . ILE A  1 321 ? 45.72851 -16.52941 0.69895   1.000 20.92224 ? 352  ILE A N   1 
ATOM   2418 C  CA  . ILE A  1 321 ? 45.64032 -15.07556 0.77925   1.000 21.85046 ? 352  ILE A CA  1 
ATOM   2419 C  C   . ILE A  1 321 ? 45.80580 -14.64964 2.23108   1.000 21.38672 ? 352  ILE A C   1 
ATOM   2420 O  O   . ILE A  1 321 ? 45.06006 -15.09711 3.11591   1.000 21.35091 ? 352  ILE A O   1 
ATOM   2421 C  CB  . ILE A  1 321 ? 44.32374 -14.55895 0.17588   1.000 20.49848 ? 352  ILE A CB  1 
ATOM   2422 C  CG1 . ILE A  1 321 ? 44.26639 -14.92353 -1.30623  1.000 22.34242 ? 352  ILE A CG1 1 
ATOM   2423 C  CG2 . ILE A  1 321 ? 44.21106 -13.05528 0.36001   1.000 23.06849 ? 352  ILE A CG2 1 
ATOM   2424 C  CD1 . ILE A  1 321 ? 42.99209 -14.47806 -2.00306  1.000 22.39204 ? 352  ILE A CD1 1 
ATOM   2425 N  N   . LYS A  1 322 ? 46.79627 -13.78649 2.46512   1.000 23.76806 ? 353  LYS A N   1 
ATOM   2426 C  CA  . LYS A  1 322 ? 47.09863 -13.30850 3.80585   1.000 21.61478 ? 353  LYS A CA  1 
ATOM   2427 C  C   . LYS A  1 322 ? 45.94165 -12.49071 4.36439   1.000 24.71651 ? 353  LYS A C   1 
ATOM   2428 O  O   . LYS A  1 322 ? 45.13134 -11.92785 3.62352   1.000 24.11857 ? 353  LYS A O   1 
ATOM   2429 C  CB  . LYS A  1 322 ? 48.36822 -12.45060 3.78479   1.000 25.69285 ? 353  LYS A CB  1 
ATOM   2430 N  N   . LYS A  1 323 ? 45.86987 -12.44317 5.68952   1.000 22.33791 ? 354  LYS A N   1 
ATOM   2431 C  CA  . LYS A  1 323 ? 44.88695 -11.61292 6.36013   1.000 23.48517 ? 354  LYS A CA  1 
ATOM   2432 C  C   . LYS A  1 323 ? 45.26755 -10.13816 6.27139   1.000 22.95695 ? 354  LYS A C   1 
ATOM   2433 O  O   . LYS A  1 323 ? 46.43365 -9.78297  6.07026   1.000 24.04113 ? 354  LYS A O   1 
ATOM   2434 C  CB  . LYS A  1 323 ? 44.76343 -12.02188 7.83154   1.000 26.69748 ? 354  LYS A CB  1 
ATOM   2435 N  N   . ASP A  1 324 ? 44.24541 -9.28031  6.37642   1.000 24.11709 ? 355  ASP A N   1 
ATOM   2436 C  CA  A ASP A  1 324 ? 44.42689 -7.83732  6.52609   0.512 22.41922 ? 355  ASP A CA  1 
ATOM   2437 C  CA  B ASP A  1 324 ? 44.40955 -7.83309  6.52181   0.488 22.42617 ? 355  ASP A CA  1 
ATOM   2438 C  C   . ASP A  1 324 ? 45.08490 -7.20015  5.30746   1.000 22.88498 ? 355  ASP A C   1 
ATOM   2439 O  O   . ASP A  1 324 ? 45.78752 -6.19212  5.42749   1.000 25.30308 ? 355  ASP A O   1 
ATOM   2440 C  CB  A ASP A  1 324 ? 45.23878 -7.50692  7.78521   0.512 26.49906 ? 355  ASP A CB  1 
ATOM   2441 C  CB  B ASP A  1 324 ? 45.18265 -7.49480  7.80180   0.488 26.50247 ? 355  ASP A CB  1 
ATOM   2442 C  CG  A ASP A  1 324 ? 44.68775 -8.17104  9.02736   0.512 27.98873 ? 355  ASP A CG  1 
ATOM   2443 C  CG  B ASP A  1 324 ? 44.82745 -6.12700  8.35632   0.488 29.06764 ? 355  ASP A CG  1 
ATOM   2444 O  OD1 A ASP A  1 324 ? 43.49244 -7.97557  9.32488   0.512 31.80101 ? 355  ASP A OD1 1 
ATOM   2445 O  OD1 B ASP A  1 324 ? 43.80976 -5.54901  7.92434   0.488 31.12666 ? 355  ASP A OD1 1 
ATOM   2446 O  OD2 A ASP A  1 324 ? 45.45325 -8.89143  9.70566   0.512 32.71116 ? 355  ASP A OD2 1 
ATOM   2447 O  OD2 B ASP A  1 324 ? 45.57106 -5.62566  9.22733   0.488 32.52456 ? 355  ASP A OD2 1 
ATOM   2448 N  N   . GLN A  1 325 ? 44.87809 -7.76435  4.12644   1.000 20.88984 ? 356  GLN A N   1 
ATOM   2449 C  CA  A GLN A  1 325 ? 45.49963 -7.19921  2.94313   0.589 20.51684 ? 356  GLN A CA  1 
ATOM   2450 C  CA  B GLN A  1 325 ? 45.47545 -7.25068  2.90065   0.411 20.55777 ? 356  GLN A CA  1 
ATOM   2451 C  C   . GLN A  1 325 ? 44.56513 -6.21151  2.25799   1.000 20.50060 ? 356  GLN A C   1 
ATOM   2452 O  O   . GLN A  1 325 ? 43.33485 -6.34850  2.28159   1.000 21.38195 ? 356  GLN A O   1 
ATOM   2453 C  CB  A GLN A  1 325 ? 45.92289 -8.29839  1.96827   0.589 21.14612 ? 356  GLN A CB  1 
ATOM   2454 C  CB  B GLN A  1 325 ? 45.73682 -8.39597  1.91535   0.411 21.19087 ? 356  GLN A CB  1 
ATOM   2455 C  CG  A GLN A  1 325 ? 46.95458 -9.26232  2.55611   0.589 22.24939 ? 356  GLN A CG  1 
ATOM   2456 C  CG  B GLN A  1 325 ? 46.27497 -7.96516  0.55715   0.411 21.42059 ? 356  GLN A CG  1 
ATOM   2457 C  CD  A GLN A  1 325 ? 48.22857 -8.56905  3.01169   0.589 23.91409 ? 356  GLN A CD  1 
ATOM   2458 C  CD  B GLN A  1 325 ? 46.38720 -9.11910  -0.43367  0.411 23.88749 ? 356  GLN A CD  1 
ATOM   2459 O  OE1 A GLN A  1 325 ? 49.08709 -8.22047  2.19466   0.589 25.06922 ? 356  GLN A OE1 1 
ATOM   2460 O  OE1 B GLN A  1 325 ? 46.34994 -10.29075 -0.05245  0.411 27.00869 ? 356  GLN A OE1 1 
ATOM   2461 N  NE2 A GLN A  1 325 ? 48.36367 -8.37501  4.32231   0.589 20.38461 ? 356  GLN A NE2 1 
ATOM   2462 N  NE2 B GLN A  1 325 ? 46.50332 -8.78923  -1.71333  0.411 18.88332 ? 356  GLN A NE2 1 
ATOM   2463 N  N   . ARG A  1 326 ? 45.17306 -5.18139  1.67624   1.000 20.48583 ? 357  ARG A N   1 
ATOM   2464 C  CA  A ARG A  1 326 ? 44.46390 -4.17179  0.89648   0.558 19.46882 ? 357  ARG A CA  1 
ATOM   2465 C  CA  B ARG A  1 326 ? 44.46677 -4.17439  0.89811   0.442 19.50345 ? 357  ARG A CA  1 
ATOM   2466 C  C   . ARG A  1 326 ? 45.12018 -4.12140  -0.47614  1.000 22.93815 ? 357  ARG A C   1 
ATOM   2467 O  O   . ARG A  1 326 ? 46.30048 -3.77523  -0.59011  1.000 25.22028 ? 357  ARG A O   1 
ATOM   2468 C  CB  A ARG A  1 326 ? 44.50801 -2.80691  1.58596   0.558 22.94923 ? 357  ARG A CB  1 
ATOM   2469 C  CB  B ARG A  1 326 ? 44.51826 -2.81072  1.59766   0.442 22.96295 ? 357  ARG A CB  1 
ATOM   2470 C  CG  A ARG A  1 326 ? 43.37318 -1.85606  1.21183   0.558 26.67715 ? 357  ARG A CG  1 
ATOM   2471 C  CG  B ARG A  1 326 ? 43.52983 -1.77838  1.08088   0.442 26.59024 ? 357  ARG A CG  1 
ATOM   2472 C  CD  A ARG A  1 326 ? 43.53340 -0.47611  1.87783   0.558 28.30087 ? 357  ARG A CD  1 
ATOM   2473 C  CD  B ARG A  1 326 ? 43.39410 -0.59862  2.05335   0.442 27.89639 ? 357  ARG A CD  1 
ATOM   2474 N  NE  A ARG A  1 326 ? 44.45925 0.38859   1.15030   0.558 24.55521 ? 357  ARG A NE  1 
ATOM   2475 N  NE  B ARG A  1 326 ? 42.60884 -0.95795  3.22635   0.442 28.18384 ? 357  ARG A NE  1 
ATOM   2476 C  CZ  A ARG A  1 326 ? 45.07826 1.43903   1.67523   0.558 30.46992 ? 357  ARG A CZ  1 
ATOM   2477 C  CZ  B ARG A  1 326 ? 41.30295 -0.75402  3.34304   0.442 26.28037 ? 357  ARG A CZ  1 
ATOM   2478 N  NH1 A ARG A  1 326 ? 44.88371 1.80027   2.93208   0.558 28.76360 ? 357  ARG A NH1 1 
ATOM   2479 N  NH1 B ARG A  1 326 ? 40.61487 -0.12441  2.40510   0.442 29.83536 ? 357  ARG A NH1 1 
ATOM   2480 N  NH2 A ARG A  1 326 ? 45.91567 2.14479   0.91966   0.558 33.14675 ? 357  ARG A NH2 1 
ATOM   2481 N  NH2 B ARG A  1 326 ? 40.67257 -1.19184  4.42774   0.442 29.73857 ? 357  ARG A NH2 1 
ATOM   2482 N  N   . PHE A  1 327 ? 44.36886 -4.49555  -1.51227  1.000 19.36772 ? 358  PHE A N   1 
ATOM   2483 C  CA  . PHE A  1 327 ? 44.87838 -4.51846  -2.88330  1.000 16.93068 ? 358  PHE A CA  1 
ATOM   2484 C  C   . PHE A  1 327 ? 44.38423 -3.26236  -3.58945  1.000 18.06137 ? 358  PHE A C   1 
ATOM   2485 O  O   . PHE A  1 327 ? 43.18411 -3.11735  -3.85244  1.000 19.29276 ? 358  PHE A O   1 
ATOM   2486 C  CB  . PHE A  1 327 ? 44.43066 -5.78431  -3.61303  1.000 17.08415 ? 358  PHE A CB  1 
ATOM   2487 C  CG  . PHE A  1 327 ? 45.13502 -6.00864  -4.92283  1.000 15.73340 ? 358  PHE A CG  1 
ATOM   2488 C  CD1 . PHE A  1 327 ? 46.34293 -6.69251  -4.95787  1.000 19.54711 ? 358  PHE A CD1 1 
ATOM   2489 C  CD2 . PHE A  1 327 ? 44.59664 -5.54907  -6.11324  1.000 19.16102 ? 358  PHE A CD2 1 
ATOM   2490 C  CE1 . PHE A  1 327 ? 47.00116 -6.91299  -6.15688  1.000 20.46924 ? 358  PHE A CE1 1 
ATOM   2491 C  CE2 . PHE A  1 327 ? 45.25682 -5.76183  -7.31602  1.000 20.09909 ? 358  PHE A CE2 1 
ATOM   2492 C  CZ  . PHE A  1 327 ? 46.46037 -6.45804  -7.33287  1.000 19.50449 ? 358  PHE A CZ  1 
ATOM   2493 N  N   . ASP A  1 328 ? 45.30792 -2.34504  -3.87879  1.000 18.59849 ? 359  ASP A N   1 
ATOM   2494 C  CA  . ASP A  1 328 ? 44.94231 -1.01515  -4.34124  1.000 18.90824 ? 359  ASP A CA  1 
ATOM   2495 C  C   . ASP A  1 328 ? 45.06022 -0.83926  -5.84740  1.000 19.05248 ? 359  ASP A C   1 
ATOM   2496 O  O   . ASP A  1 328 ? 44.65068 0.20718   -6.36525  1.000 20.32970 ? 359  ASP A O   1 
ATOM   2497 C  CB  . ASP A  1 328 ? 45.81232 0.03859   -3.64199  1.000 19.70536 ? 359  ASP A CB  1 
ATOM   2498 C  CG  . ASP A  1 328 ? 45.58718 0.08081   -2.14847  1.000 25.28372 ? 359  ASP A CG  1 
ATOM   2499 O  OD1 . ASP A  1 328 ? 44.43260 -0.10647  -1.70938  1.000 23.61804 ? 359  ASP A OD1 1 
ATOM   2500 O  OD2 . ASP A  1 328 ? 46.56636 0.31159   -1.40883  1.000 26.13650 ? 359  ASP A OD2 1 
ATOM   2501 N  N   . PHE A  1 329 ? 45.60160 -1.82640  -6.56488  1.000 18.70572 ? 360  PHE A N   1 
ATOM   2502 C  CA  . PHE A  1 329 ? 45.69706 -1.69263  -8.01291  1.000 19.09158 ? 360  PHE A CA  1 
ATOM   2503 C  C   . PHE A  1 329 ? 44.35916 -2.03292  -8.65870  1.000 17.96596 ? 360  PHE A C   1 
ATOM   2504 O  O   . PHE A  1 329 ? 43.65495 -2.92796  -8.18255  1.000 19.30464 ? 360  PHE A O   1 
ATOM   2505 C  CB  . PHE A  1 329 ? 46.77974 -2.61710  -8.56911  1.000 20.83937 ? 360  PHE A CB  1 
ATOM   2506 C  CG  . PHE A  1 329 ? 48.15434 -2.33543  -8.02335  1.000 22.19957 ? 360  PHE A CG  1 
ATOM   2507 C  CD1 . PHE A  1 329 ? 48.77898 -1.12225  -8.27898  1.000 21.01447 ? 360  PHE A CD1 1 
ATOM   2508 C  CD2 . PHE A  1 329 ? 48.81699 -3.28981  -7.26219  1.000 23.68901 ? 360  PHE A CD2 1 
ATOM   2509 C  CE1 . PHE A  1 329 ? 50.04641 -0.86521  -7.78307  1.000 21.55180 ? 360  PHE A CE1 1 
ATOM   2510 C  CE2 . PHE A  1 329 ? 50.08362 -3.03533  -6.75636  1.000 23.94805 ? 360  PHE A CE2 1 
ATOM   2511 C  CZ  . PHE A  1 329 ? 50.69087 -1.82672  -7.02021  1.000 21.29013 ? 360  PHE A CZ  1 
ATOM   2512 N  N   . PRO A  1 330 ? 43.98826 -1.33555  -9.72993  1.000 17.25178 ? 361  PRO A N   1 
ATOM   2513 C  CA  . PRO A  1 330 ? 42.68794 -1.59572  -10.36032 1.000 17.32116 ? 361  PRO A CA  1 
ATOM   2514 C  C   . PRO A  1 330 ? 42.58505 -3.01976  -10.89058 1.000 18.44774 ? 361  PRO A C   1 
ATOM   2515 O  O   . PRO A  1 330 ? 43.54773 -3.59328  -11.41207 1.000 17.78130 ? 361  PRO A O   1 
ATOM   2516 C  CB  . PRO A  1 330 ? 42.61665 -0.56115  -11.49094 1.000 19.44596 ? 361  PRO A CB  1 
ATOM   2517 C  CG  . PRO A  1 330 ? 43.98381 0.03059   -11.61448 1.000 23.88491 ? 361  PRO A CG  1 
ATOM   2518 C  CD  . PRO A  1 330 ? 44.67985 -0.16885  -10.30554 1.000 20.30719 ? 361  PRO A CD  1 
ATOM   2519 N  N   . VAL A  1 331 ? 41.40018 -3.60111  -10.71943 1.000 16.64973 ? 362  VAL A N   1 
ATOM   2520 C  CA  . VAL A  1 331 ? 41.07043 -4.92092  -11.24552 1.000 16.77781 ? 362  VAL A CA  1 
ATOM   2521 C  C   . VAL A  1 331 ? 39.66255 -4.85396  -11.82496 1.000 16.13366 ? 362  VAL A C   1 
ATOM   2522 O  O   . VAL A  1 331 ? 38.92357 -3.88693  -11.61451 1.000 17.71507 ? 362  VAL A O   1 
ATOM   2523 C  CB  . VAL A  1 331 ? 41.15031 -6.02172  -10.16980 1.000 17.19461 ? 362  VAL A CB  1 
ATOM   2524 C  CG1 . VAL A  1 331 ? 42.56424 -6.11496  -9.60411  1.000 17.81075 ? 362  VAL A CG1 1 
ATOM   2525 C  CG2 . VAL A  1 331 ? 40.12821 -5.75269  -9.07773  1.000 18.04356 ? 362  VAL A CG2 1 
ATOM   2526 N  N   . SER A  1 332 ? 39.28394 -5.91519  -12.53995 1.000 16.90295 ? 363  SER A N   1 
ATOM   2527 C  CA  . SER A  1 332 ? 37.99653 -5.98576  -13.21859 1.000 17.44367 ? 363  SER A CA  1 
ATOM   2528 C  C   . SER A  1 332 ? 37.27968 -7.29171  -12.89485 1.000 16.10547 ? 363  SER A C   1 
ATOM   2529 O  O   . SER A  1 332 ? 37.90818 -8.33814  -12.71004 1.000 16.03179 ? 363  SER A O   1 
ATOM   2530 C  CB  . SER A  1 332 ? 38.18099 -5.88178  -14.73984 1.000 16.53165 ? 363  SER A CB  1 
ATOM   2531 O  OG  . SER A  1 332 ? 36.94619 -6.11367  -15.40766 1.000 17.35879 ? 363  SER A OG  1 
ATOM   2532 N  N   . SER A  1 333 ? 35.94301 -7.22898  -12.85023 1.000 16.53339 ? 364  SER A N   1 
ATOM   2533 C  CA  . SER A  1 333 ? 35.16769 -8.46085  -12.77095 1.000 15.69953 ? 364  SER A CA  1 
ATOM   2534 C  C   . SER A  1 333 ? 35.43359 -9.38158  -13.95960 1.000 17.87306 ? 364  SER A C   1 
ATOM   2535 O  O   . SER A  1 333 ? 35.18618 -10.58661 -13.85932 1.000 18.15965 ? 364  SER A O   1 
ATOM   2536 C  CB  . SER A  1 333 ? 33.67777 -8.12887  -12.67621 1.000 15.49502 ? 364  SER A CB  1 
ATOM   2537 O  OG  . SER A  1 333 ? 33.24082 -7.49047  -13.86971 1.000 16.68507 ? 364  SER A OG  1 
ATOM   2538 N  N   . LEU A  1 334 ? 35.91730 -8.84050  -15.08453 1.000 16.91743 ? 365  LEU A N   1 
ATOM   2539 C  CA  . LEU A  1 334 ? 36.37485 -9.68626  -16.18516 1.000 16.32843 ? 365  LEU A CA  1 
ATOM   2540 C  C   . LEU A  1 334 ? 37.52994 -10.58454 -15.77835 1.000 16.37067 ? 365  LEU A C   1 
ATOM   2541 O  O   . LEU A  1 334 ? 37.78842 -11.59064 -16.45178 1.000 18.85235 ? 365  LEU A O   1 
ATOM   2542 C  CB  . LEU A  1 334 ? 36.79994 -8.81507  -17.37289 1.000 15.68561 ? 365  LEU A CB  1 
ATOM   2543 C  CG  . LEU A  1 334 ? 35.67805 -7.97923  -18.00133 1.000 18.40278 ? 365  LEU A CG  1 
ATOM   2544 C  CD1 . LEU A  1 334 ? 36.26760 -6.86327  -18.85475 1.000 19.67950 ? 365  LEU A CD1 1 
ATOM   2545 C  CD2 . LEU A  1 334 ? 34.73995 -8.86929  -18.82752 1.000 17.79810 ? 365  LEU A CD2 1 
ATOM   2546 N  N   . ASP A  1 335 ? 38.22909 -10.25163 -14.69136 1.000 15.64630 ? 366  ASP A N   1 
ATOM   2547 C  CA  . ASP A  1 335 ? 39.33699 -11.09715 -14.26308 1.000 17.33853 ? 366  ASP A CA  1 
ATOM   2548 C  C   . ASP A  1 335 ? 38.85739 -12.40800 -13.66253 1.000 18.20290 ? 366  ASP A C   1 
ATOM   2549 O  O   . ASP A  1 335 ? 39.64585 -13.35190 -13.55314 1.000 18.25090 ? 366  ASP A O   1 
ATOM   2550 C  CB  . ASP A  1 335 ? 40.21778 -10.35647 -13.24645 1.000 17.83820 ? 366  ASP A CB  1 
ATOM   2551 C  CG  . ASP A  1 335 ? 40.81501 -9.07568  -13.80917 1.000 19.43326 ? 366  ASP A CG  1 
ATOM   2552 O  OD1 . ASP A  1 335 ? 41.00410 -8.98417  -15.04357 1.000 19.21138 ? 366  ASP A OD1 1 
ATOM   2553 O  OD2 . ASP A  1 335 ? 41.08759 -8.14826  -13.01269 1.000 17.98921 ? 366  ASP A OD2 1 
ATOM   2554 N  N   . LEU A  1 336 ? 37.58849 -12.49840 -13.25930 1.000 19.38849 ? 367  LEU A N   1 
ATOM   2555 C  CA  . LEU A  1 336 ? 37.15245 -13.69961 -12.55317 1.000 16.14797 ? 367  LEU A CA  1 
ATOM   2556 C  C   . LEU A  1 336 ? 37.23159 -14.93915 -13.44421 1.000 18.23613 ? 367  LEU A C   1 
ATOM   2557 O  O   . LEU A  1 336 ? 37.67660 -15.99862 -12.99498 1.000 18.26213 ? 367  LEU A O   1 
ATOM   2558 C  CB  . LEU A  1 336 ? 35.73588 -13.50887 -12.00617 1.000 16.44062 ? 367  LEU A CB  1 
ATOM   2559 C  CG  . LEU A  1 336 ? 35.60437 -12.36254 -10.99323 1.000 17.33429 ? 367  LEU A CG  1 
ATOM   2560 C  CD1 . LEU A  1 336 ? 34.20755 -12.35981 -10.37141 1.000 19.25104 ? 367  LEU A CD1 1 
ATOM   2561 C  CD2 . LEU A  1 336 ? 36.69900 -12.40505 -9.90318  1.000 18.17096 ? 367  LEU A CD2 1 
ATOM   2562 N  N   . TYR A  1 337 ? 36.83403 -14.82061 -14.71461 1.000 18.29633 ? 368  TYR A N   1 
ATOM   2563 C  CA  . TYR A  1 337 ? 36.84839 -15.98254 -15.60586 1.000 17.19460 ? 368  TYR A CA  1 
ATOM   2564 C  C   . TYR A  1 337 ? 38.24800 -16.57954 -15.74011 1.000 17.45310 ? 368  TYR A C   1 
ATOM   2565 O  O   . TYR A  1 337 ? 38.43153 -17.75892 -15.38075 1.000 19.42152 ? 368  TYR A O   1 
ATOM   2566 C  CB  . TYR A  1 337 ? 36.20689 -15.56611 -16.93715 1.000 17.71803 ? 368  TYR A CB  1 
ATOM   2567 C  CG  . TYR A  1 337 ? 35.84013 -16.65416 -17.92773 1.000 18.01516 ? 368  TYR A CG  1 
ATOM   2568 C  CD1 . TYR A  1 337 ? 36.72932 -17.66853 -18.26472 1.000 19.90267 ? 368  TYR A CD1 1 
ATOM   2569 C  CD2 . TYR A  1 337 ? 34.60434 -16.62642 -18.55877 1.000 18.96639 ? 368  TYR A CD2 1 
ATOM   2570 C  CE1 . TYR A  1 337 ? 36.38033 -18.64158 -19.19391 1.000 21.57742 ? 368  TYR A CE1 1 
ATOM   2571 C  CE2 . TYR A  1 337 ? 34.24940 -17.58940 -19.49200 1.000 18.39915 ? 368  TYR A CE2 1 
ATOM   2572 C  CZ  . TYR A  1 337 ? 35.14048 -18.58487 -19.80170 1.000 19.62221 ? 368  TYR A CZ  1 
ATOM   2573 O  OH  . TYR A  1 337 ? 34.77392 -19.53702 -20.72614 1.000 20.47159 ? 368  TYR A OH  1 
ATOM   2574 N  N   . PRO A  1 338 ? 39.26992 -15.84960 -16.21332 1.000 19.09097 ? 369  PRO A N   1 
ATOM   2575 C  CA  . PRO A  1 338 ? 40.60267 -16.48082 -16.32220 1.000 18.95584 ? 369  PRO A CA  1 
ATOM   2576 C  C   . PRO A  1 338 ? 41.21965 -16.83110 -14.98472 1.000 20.52527 ? 369  PRO A C   1 
ATOM   2577 O  O   . PRO A  1 338 ? 41.98690 -17.80098 -14.90487 1.000 21.67780 ? 369  PRO A O   1 
ATOM   2578 C  CB  . PRO A  1 338 ? 41.44169 -15.43279 -17.06364 1.000 18.99136 ? 369  PRO A CB  1 
ATOM   2579 C  CG  . PRO A  1 338 ? 40.71185 -14.11806 -16.83821 1.000 17.53498 ? 369  PRO A CG  1 
ATOM   2580 C  CD  . PRO A  1 338 ? 39.26224 -14.47243 -16.75412 1.000 16.68890 ? 369  PRO A CD  1 
ATOM   2581 N  N   . THR A  1 339 ? 40.93914 -16.06388 -13.93171 1.000 18.30986 ? 370  THR A N   1 
ATOM   2582 C  CA  . THR A  1 339 ? 41.46580 -16.42027 -12.61983 1.000 17.87595 ? 370  THR A CA  1 
ATOM   2583 C  C   . THR A  1 339 ? 40.88315 -17.74690 -12.14094 1.000 19.82257 ? 370  THR A C   1 
ATOM   2584 O  O   . THR A  1 339 ? 41.61859 -18.62408 -11.66842 1.000 19.40979 ? 370  THR A O   1 
ATOM   2585 C  CB  . THR A  1 339 ? 41.17589 -15.30883 -11.61053 1.000 18.47535 ? 370  THR A CB  1 
ATOM   2586 O  OG1 . THR A  1 339 ? 41.79363 -14.09704 -12.06121 1.000 18.01963 ? 370  THR A OG1 1 
ATOM   2587 C  CG2 . THR A  1 339 ? 41.73070 -15.68198 -10.22901 1.000 20.30711 ? 370  THR A CG2 1 
ATOM   2588 N  N   . PHE A  1 340 ? 39.55688 -17.91272 -12.26345 1.000 19.49600 ? 371  PHE A N   1 
ATOM   2589 C  CA  . PHE A  1 340 ? 38.91119 -19.13398 -11.79286 1.000 19.49857 ? 371  PHE A CA  1 
ATOM   2590 C  C   . PHE A  1 340 ? 39.31704 -20.33266 -12.63999 1.000 19.55651 ? 371  PHE A C   1 
ATOM   2591 O  O   . PHE A  1 340 ? 39.54746 -21.42093 -12.10725 1.000 20.60135 ? 371  PHE A O   1 
ATOM   2592 C  CB  . PHE A  1 340 ? 37.38843 -18.99107 -11.81721 1.000 18.74330 ? 371  PHE A CB  1 
ATOM   2593 C  CG  . PHE A  1 340 ? 36.83017 -18.01194 -10.80828 1.000 18.41906 ? 371  PHE A CG  1 
ATOM   2594 C  CD1 . PHE A  1 340 ? 37.61914 -17.46898 -9.80191  1.000 17.84018 ? 371  PHE A CD1 1 
ATOM   2595 C  CD2 . PHE A  1 340 ? 35.49652 -17.64654 -10.88001 1.000 18.48524 ? 371  PHE A CD2 1 
ATOM   2596 C  CE1 . PHE A  1 340 ? 37.07393 -16.56307 -8.88241  1.000 17.57611 ? 371  PHE A CE1 1 
ATOM   2597 C  CE2 . PHE A  1 340 ? 34.93949 -16.75600 -9.97773  1.000 18.63682 ? 371  PHE A CE2 1 
ATOM   2598 C  CZ  . PHE A  1 340 ? 35.72874 -16.19945 -8.98083  1.000 19.64777 ? 371  PHE A CZ  1 
ATOM   2599 N  N   . THR A  1 341 ? 39.38212 -20.17034 -13.96287 1.000 20.13599 ? 372  THR A N   1 
ATOM   2600 C  CA  . THR A  1 341 ? 39.75242 -21.33075 -14.76452 1.000 22.63153 ? 372  THR A CA  1 
ATOM   2601 C  C   . THR A  1 341 ? 41.21230 -21.70490 -14.54196 1.000 22.70598 ? 372  THR A C   1 
ATOM   2602 O  O   . THR A  1 341 ? 41.55975 -22.89127 -14.58780 1.000 23.89560 ? 372  THR A O   1 
ATOM   2603 C  CB  . THR A  1 341 ? 39.44965 -21.09289 -16.24932 1.000 23.03949 ? 372  THR A CB  1 
ATOM   2604 O  OG1 . THR A  1 341 ? 40.14486 -19.94019 -16.72954 1.000 25.85346 ? 372  THR A OG1 1 
ATOM   2605 C  CG2 . THR A  1 341 ? 37.95314 -20.91408 -16.45888 1.000 26.19172 ? 372  THR A CG2 1 
ATOM   2606 N  N   . GLY A  1 342 ? 42.06974 -20.72265 -14.25458 1.000 23.93876 ? 373  GLY A N   1 
ATOM   2607 C  CA  . GLY A  1 342 ? 43.43931 -21.04161 -13.88189 1.000 23.23318 ? 373  GLY A CA  1 
ATOM   2608 C  C   . GLY A  1 342 ? 43.52182 -21.82992 -12.58835 1.000 24.83677 ? 373  GLY A C   1 
ATOM   2609 O  O   . GLY A  1 342 ? 44.25379 -22.81943 -12.49146 1.000 26.04721 ? 373  GLY A O   1 
ATOM   2610 N  N   . LEU A  1 343 ? 42.77180 -21.39817 -11.56978 1.000 21.96905 ? 374  LEU A N   1 
ATOM   2611 C  CA  . LEU A  1 343 ? 42.75067 -22.12817 -10.30455 1.000 23.38549 ? 374  LEU A CA  1 
ATOM   2612 C  C   . LEU A  1 343 ? 42.23071 -23.54286 -10.48386 1.000 22.43350 ? 374  LEU A C   1 
ATOM   2613 O  O   . LEU A  1 343 ? 42.65883 -24.46465 -9.77552  1.000 25.24026 ? 374  LEU A O   1 
ATOM   2614 C  CB  . LEU A  1 343 ? 41.88196 -21.39733 -9.28380  1.000 23.58971 ? 374  LEU A CB  1 
ATOM   2615 C  CG  . LEU A  1 343 ? 42.40324 -20.03055 -8.85414  1.000 22.98817 ? 374  LEU A CG  1 
ATOM   2616 C  CD1 . LEU A  1 343 ? 41.40528 -19.37625 -7.91450  1.000 27.53788 ? 374  LEU A CD1 1 
ATOM   2617 C  CD2 . LEU A  1 343 ? 43.76049 -20.17609 -8.19387  1.000 26.55524 ? 374  LEU A CD2 1 
ATOM   2618 N  N   . ALA A  1 344 ? 41.26944 -23.72334 -11.38316 1.000 21.31717 ? 375  ALA A N   1 
ATOM   2619 C  CA  . ALA A  1 344 ? 40.68450 -25.02833 -11.64359 1.000 23.21971 ? 375  ALA A CA  1 
ATOM   2620 C  C   . ALA A  1 344 ? 41.53374 -25.87584 -12.57257 1.000 25.79524 ? 375  ALA A C   1 
ATOM   2621 O  O   . ALA A  1 344 ? 41.13799 -27.00586 -12.87637 1.000 24.31998 ? 375  ALA A O   1 
ATOM   2622 C  CB  . ALA A  1 344 ? 39.29282 -24.87122 -12.24707 1.000 22.36120 ? 375  ALA A CB  1 
ATOM   2623 N  N   . GLU A  1 345 ? 42.66232 -25.34778 -13.05039 1.000 25.84580 ? 376  GLU A N   1 
ATOM   2624 C  CA  . GLU A  1 345 ? 43.51617 -26.05630 -14.00327 1.000 26.09403 ? 376  GLU A CA  1 
ATOM   2625 C  C   . GLU A  1 345 ? 42.71254 -26.49712 -15.22191 1.000 30.32507 ? 376  GLU A C   1 
ATOM   2626 O  O   . GLU A  1 345 ? 42.93454 -27.56902 -15.79074 1.000 31.68230 ? 376  GLU A O   1 
ATOM   2627 C  CB  . GLU A  1 345 ? 44.20634 -27.24743 -13.33461 1.000 26.12568 ? 376  GLU A CB  1 
ATOM   2628 C  CG  . GLU A  1 345 ? 44.94723 -26.85237 -12.07706 1.000 32.48241 ? 376  GLU A CG  1 
ATOM   2629 C  CD  . GLU A  1 345 ? 45.68191 -28.01204 -11.43179 1.000 44.43757 ? 376  GLU A CD  1 
ATOM   2630 O  OE1 . GLU A  1 345 ? 45.13806 -29.13921 -11.42642 1.000 44.21231 ? 376  GLU A OE1 1 
ATOM   2631 O  OE2 . GLU A  1 345 ? 46.80346 -27.78757 -10.92798 1.000 51.14986 ? 376  GLU A OE2 1 
ATOM   2632 N  N   . ALA A  1 346 ? 41.75736 -25.66139 -15.61803 1.000 27.29193 ? 377  ALA A N   1 
ATOM   2633 C  CA  . ALA A  1 346 ? 40.83007 -25.98903 -16.68351 1.000 29.29498 ? 377  ALA A CA  1 
ATOM   2634 C  C   . ALA A  1 346 ? 41.34573 -25.45501 -18.00818 1.000 32.88603 ? 377  ALA A C   1 
ATOM   2635 O  O   . ALA A  1 346 ? 41.92435 -24.36597 -18.07022 1.000 40.30789 ? 377  ALA A O   1 
ATOM   2636 C  CB  . ALA A  1 346 ? 39.44916 -25.40743 -16.38937 1.000 26.35754 ? 377  ALA A CB  1 
ATOM   2637 N  N   . LYS A  1 347 ? 41.14410 -26.23400 -19.06405 1.000 35.02869 ? 378  LYS A N   1 
ATOM   2638 C  CA  . LYS A  1 347 ? 41.48065 -25.77918 -20.40192 1.000 39.34272 ? 378  LYS A CA  1 
ATOM   2639 C  C   . LYS A  1 347 ? 40.32256 -24.97715 -20.98153 1.000 31.76436 ? 378  LYS A C   1 
ATOM   2640 O  O   . LYS A  1 347 ? 39.15271 -25.34075 -20.81811 1.000 33.84944 ? 378  LYS A O   1 
ATOM   2641 C  CB  . LYS A  1 347 ? 41.80894 -26.96745 -21.30938 1.000 39.16915 ? 378  LYS A CB  1 
ATOM   2642 N  N   . LEU A  1 348 ? 40.65459 -23.87347 -21.63847 1.000 33.24575 ? 379  LEU A N   1 
ATOM   2643 C  CA  . LEU A  1 348 ? 39.64898 -23.06313 -22.30071 1.000 33.02554 ? 379  LEU A CA  1 
ATOM   2644 C  C   . LEU A  1 348 ? 39.20997 -23.72434 -23.60233 1.000 32.65833 ? 379  LEU A C   1 
ATOM   2645 O  O   . LEU A  1 348 ? 40.01286 -24.38592 -24.26833 1.000 30.20885 ? 379  LEU A O   1 
ATOM   2646 C  CB  . LEU A  1 348 ? 40.19444 -21.67598 -22.60783 1.000 28.92630 ? 379  LEU A CB  1 
ATOM   2647 C  CG  . LEU A  1 348 ? 40.50721 -20.76278 -21.42324 1.000 38.03879 ? 379  LEU A CG  1 
ATOM   2648 C  CD1 . LEU A  1 348 ? 40.98422 -19.41885 -21.93767 1.000 35.16845 ? 379  LEU A CD1 1 
ATOM   2649 C  CD2 . LEU A  1 348 ? 39.28127 -20.60758 -20.53170 1.000 34.08816 ? 379  LEU A CD2 1 
ATOM   2650 N  N   . PRO A  1 349 ? 37.94717 -23.54906 -23.99126 1.000 29.80722 ? 380  PRO A N   1 
ATOM   2651 C  CA  . PRO A  1 349 ? 37.51990 -24.01990 -25.30994 1.000 31.10810 ? 380  PRO A CA  1 
ATOM   2652 C  C   . PRO A  1 349 ? 38.34452 -23.34240 -26.38853 1.000 34.59970 ? 380  PRO A C   1 
ATOM   2653 O  O   . PRO A  1 349 ? 38.75381 -22.18804 -26.24902 1.000 29.46539 ? 380  PRO A O   1 
ATOM   2654 C  CB  . PRO A  1 349 ? 36.04759 -23.59655 -25.38934 1.000 35.33914 ? 380  PRO A CB  1 
ATOM   2655 C  CG  . PRO A  1 349 ? 35.64807 -23.25389 -23.99430 1.000 32.63271 ? 380  PRO A CG  1 
ATOM   2656 C  CD  . PRO A  1 349 ? 36.88410 -22.79975 -23.29897 1.000 31.21728 ? 380  PRO A CD  1 
ATOM   2657 N  N   . LYS A  1 350 ? 38.60394 -24.08193 -27.46651 1.000 32.93224 ? 381  LYS A N   1 
ATOM   2658 C  CA  . LYS A  1 350 ? 39.37547 -23.53054 -28.57258 1.000 31.64980 ? 381  LYS A CA  1 
ATOM   2659 C  C   . LYS A  1 350 ? 38.69936 -22.27645 -29.11312 1.000 31.14475 ? 381  LYS A C   1 
ATOM   2660 O  O   . LYS A  1 350 ? 37.48487 -22.25459 -29.33369 1.000 31.33508 ? 381  LYS A O   1 
ATOM   2661 C  CB  . LYS A  1 350 ? 39.53158 -24.57666 -29.68054 1.000 34.46899 ? 381  LYS A CB  1 
ATOM   2662 N  N   . GLY A  1 351 ? 39.48454 -21.21653 -29.28680 1.000 30.15735 ? 382  GLY A N   1 
ATOM   2663 C  CA  . GLY A  1 351 ? 38.97593 -19.97765 -29.83325 1.000 34.34797 ? 382  GLY A CA  1 
ATOM   2664 C  C   . GLY A  1 351 ? 38.30490 -19.05478 -28.83699 1.000 31.65167 ? 382  GLY A C   1 
ATOM   2665 O  O   . GLY A  1 351 ? 37.88293 -17.95792 -29.22485 1.000 30.78473 ? 382  GLY A O   1 
ATOM   2666 N  N   . LYS A  1 352 ? 38.18879 -19.45773 -27.57440 1.000 29.61202 ? 383  LYS A N   1 
ATOM   2667 C  CA  . LYS A  1 352 ? 37.57006 -18.59204 -26.57612 1.000 27.76605 ? 383  LYS A CA  1 
ATOM   2668 C  C   . LYS A  1 352 ? 38.40336 -17.33378 -26.39307 1.000 25.13419 ? 383  LYS A C   1 
ATOM   2669 O  O   . LYS A  1 352 ? 39.62389 -17.40527 -26.21438 1.000 26.99938 ? 383  LYS A O   1 
ATOM   2670 C  CB  . LYS A  1 352 ? 37.43847 -19.32839 -25.24319 1.000 26.88849 ? 383  LYS A CB  1 
ATOM   2671 C  CG  . LYS A  1 352 ? 36.90539 -18.45108 -24.09441 1.000 26.14079 ? 383  LYS A CG  1 
ATOM   2672 C  CD  . LYS A  1 352 ? 35.43751 -18.12805 -24.27051 1.000 24.39157 ? 383  LYS A CD  1 
ATOM   2673 C  CE  . LYS A  1 352 ? 34.99104 -17.08900 -23.22031 1.000 23.77453 ? 383  LYS A CE  1 
ATOM   2674 N  NZ  . LYS A  1 352 ? 33.54382 -16.79561 -23.28709 1.000 25.35353 ? 383  LYS A NZ  1 
ATOM   2675 N  N   . GLN A  1 353 ? 37.73915 -16.18026 -26.42274 1.000 24.16713 ? 384  GLN A N   1 
ATOM   2676 C  CA  . GLN A  1 353 ? 38.37873 -14.88842 -26.21805 1.000 23.71497 ? 384  GLN A CA  1 
ATOM   2677 C  C   . GLN A  1 353 ? 37.98356 -14.33541 -24.85644 1.000 23.52692 ? 384  GLN A C   1 
ATOM   2678 O  O   . GLN A  1 353 ? 36.83396 -14.48386 -24.43013 1.000 21.62999 ? 384  GLN A O   1 
ATOM   2679 C  CB  . GLN A  1 353 ? 37.97498 -13.89242 -27.30316 1.000 26.47829 ? 384  GLN A CB  1 
ATOM   2680 C  CG  . GLN A  1 353 ? 38.42686 -14.26399 -28.70707 1.000 34.42345 ? 384  GLN A CG  1 
ATOM   2681 C  CD  . GLN A  1 353 ? 37.83717 -13.34212 -29.76153 1.000 43.48978 ? 384  GLN A CD  1 
ATOM   2682 O  OE1 . GLN A  1 353 ? 38.32569 -12.22906 -29.97754 1.000 50.61273 ? 384  GLN A OE1 1 
ATOM   2683 N  NE2 . GLN A  1 353 ? 36.77035 -13.79625 -30.41558 1.000 45.04414 ? 384  GLN A NE2 1 
ATOM   2684 N  N   . LEU A  1 354 ? 38.94255 -13.70547 -24.18188 1.000 22.59985 ? 385  LEU A N   1 
ATOM   2685 C  CA  . LEU A  1 354 ? 38.74805 -13.16521 -22.84272 1.000 21.08763 ? 385  LEU A CA  1 
ATOM   2686 C  C   . LEU A  1 354 ? 39.32518 -11.75903 -22.78066 1.000 24.42899 ? 385  LEU A C   1 
ATOM   2687 O  O   . LEU A  1 354 ? 40.39491 -11.49197 -23.33573 1.000 24.43045 ? 385  LEU A O   1 
ATOM   2688 C  CB  . LEU A  1 354 ? 39.41847 -14.04453 -21.77961 1.000 20.75469 ? 385  LEU A CB  1 
ATOM   2689 C  CG  . LEU A  1 354 ? 38.82832 -15.43419 -21.55839 1.000 22.43928 ? 385  LEU A CG  1 
ATOM   2690 C  CD1 . LEU A  1 354 ? 39.72745 -16.24583 -20.63156 1.000 23.17861 ? 385  LEU A CD1 1 
ATOM   2691 C  CD2 . LEU A  1 354 ? 37.41385 -15.31364 -20.98711 1.000 21.01827 ? 385  LEU A CD2 1 
ATOM   2692 N  N   . ASP A  1 355 ? 38.62366 -10.86194 -22.08504 1.000 20.55780 ? 386  ASP A N   1 
ATOM   2693 C  CA  . ASP A  1 355 ? 39.07569 -9.48662  -21.94040 1.000 20.85064 ? 386  ASP A CA  1 
ATOM   2694 C  C   . ASP A  1 355 ? 39.75961 -9.20446  -20.60407 1.000 24.81099 ? 386  ASP A C   1 
ATOM   2695 O  O   . ASP A  1 355 ? 40.33875 -8.12483  -20.44010 1.000 26.87429 ? 386  ASP A O   1 
ATOM   2696 C  CB  . ASP A  1 355 ? 37.88837 -8.53139  -22.12128 1.000 21.80369 ? 386  ASP A CB  1 
ATOM   2697 C  CG  . ASP A  1 355 ? 37.41894 -8.45713  -23.55996 1.000 24.96626 ? 386  ASP A CG  1 
ATOM   2698 O  OD1 . ASP A  1 355 ? 38.27752 -8.52504  -24.47429 1.000 31.80425 ? 386  ASP A OD1 1 
ATOM   2699 O  OD2 . ASP A  1 355 ? 36.20119 -8.32948  -23.78736 1.000 22.65949 ? 386  ASP A OD2 1 
ATOM   2700 N  N   . GLY A  1 356 ? 39.70296 -10.13226 -19.64898 1.000 19.07517 ? 387  GLY A N   1 
ATOM   2701 C  CA  . GLY A  1 356 ? 40.31263 -9.94988  -18.35161 1.000 18.72918 ? 387  GLY A CA  1 
ATOM   2702 C  C   . GLY A  1 356 ? 41.60981 -10.72905 -18.21943 1.000 22.36385 ? 387  GLY A C   1 
ATOM   2703 O  O   . GLY A  1 356 ? 42.13194 -11.29499 -19.18129 1.000 22.73345 ? 387  GLY A O   1 
ATOM   2704 N  N   . LYS A  1 357 ? 42.12880 -10.75969 -16.98989 1.000 20.05727 ? 388  LYS A N   1 
ATOM   2705 C  CA  . LYS A  1 357 ? 43.43354 -11.33549 -16.69651 1.000 20.43235 ? 388  LYS A CA  1 
ATOM   2706 C  C   . LYS A  1 357 ? 43.32473 -12.31490 -15.53748 1.000 21.59576 ? 388  LYS A C   1 
ATOM   2707 O  O   . LYS A  1 357 ? 42.50553 -12.13565 -14.63124 1.000 19.63920 ? 388  LYS A O   1 
ATOM   2708 C  CB  . LYS A  1 357 ? 44.46347 -10.23811 -16.32851 1.000 22.85637 ? 388  LYS A CB  1 
ATOM   2709 C  CG  . LYS A  1 357 ? 44.69288 -9.18852  -17.40305 1.000 25.05861 ? 388  LYS A CG  1 
ATOM   2710 C  CD  . LYS A  1 357 ? 45.61215 -8.08098  -16.89767 1.000 24.91620 ? 388  LYS A CD  1 
ATOM   2711 C  CE  . LYS A  1 357 ? 45.87701 -7.07442  -17.98223 1.000 27.00492 ? 388  LYS A CE  1 
ATOM   2712 N  NZ  . LYS A  1 357 ? 46.64990 -7.69765  -19.08275 1.000 32.39626 ? 388  LYS A NZ  1 
ATOM   2713 N  N   . ASN A  1 358 ? 44.16351 -13.34889 -15.56449 1.000 19.74470 ? 389  ASN A N   1 
ATOM   2714 C  CA  . ASN A  1 358 ? 44.36209 -14.19664 -14.39215 1.000 19.47967 ? 389  ASN A CA  1 
ATOM   2715 C  C   . ASN A  1 358 ? 45.19475 -13.40396 -13.39439 1.000 22.43219 ? 389  ASN A C   1 
ATOM   2716 O  O   . ASN A  1 358 ? 46.40313 -13.23346 -13.57291 1.000 23.43122 ? 389  ASN A O   1 
ATOM   2717 C  CB  . ASN A  1 358 ? 45.05207 -15.49963 -14.79124 1.000 21.19277 ? 389  ASN A CB  1 
ATOM   2718 C  CG  . ASN A  1 358 ? 45.27670 -16.42744 -13.62117 1.000 22.24840 ? 389  ASN A CG  1 
ATOM   2719 O  OD1 . ASN A  1 358 ? 45.09928 -16.05603 -12.45853 1.000 22.51863 ? 389  ASN A OD1 1 
ATOM   2720 N  ND2 . ASN A  1 358 ? 45.67820 -17.66355 -13.92499 1.000 29.76500 ? 389  ASN A ND2 1 
ATOM   2721 N  N   . ILE A  1 359 ? 44.56034 -12.90585 -12.33160 1.000 19.67154 ? 390  ILE A N   1 
ATOM   2722 C  CA  . ILE A  1 359 ? 45.21958 -11.95382 -11.44111 1.000 19.77725 ? 390  ILE A CA  1 
ATOM   2723 C  C   . ILE A  1 359 ? 45.68876 -12.58543 -10.13147 1.000 19.85446 ? 390  ILE A C   1 
ATOM   2724 O  O   . ILE A  1 359 ? 46.19092 -11.86290 -9.26606  1.000 20.68410 ? 390  ILE A O   1 
ATOM   2725 C  CB  . ILE A  1 359 ? 44.32361 -10.73778 -11.14087 1.000 20.94514 ? 390  ILE A CB  1 
ATOM   2726 C  CG1 . ILE A  1 359 ? 43.02756 -11.15913 -10.42825 1.000 20.31398 ? 390  ILE A CG1 1 
ATOM   2727 C  CG2 . ILE A  1 359 ? 44.00967 -9.96559  -12.40470 1.000 20.18832 ? 390  ILE A CG2 1 
ATOM   2728 C  CD1 . ILE A  1 359 ? 42.30424 -9.98497  -9.75799  1.000 18.61091 ? 390  ILE A CD1 1 
ATOM   2729 N  N   . MET A  1 360 ? 45.55920 -13.90782 -9.95806  1.000 22.53615 ? 391  MET A N   1 
ATOM   2730 C  CA  . MET A  1 360 ? 45.82117 -14.46481 -8.63003  1.000 21.73754 ? 391  MET A CA  1 
ATOM   2731 C  C   . MET A  1 360 ? 47.27967 -14.26784 -8.21487  1.000 22.86939 ? 391  MET A C   1 
ATOM   2732 O  O   . MET A  1 360 ? 47.55662 -13.90480 -7.06805  1.000 24.06709 ? 391  MET A O   1 
ATOM   2733 C  CB  . MET A  1 360 ? 45.42267 -15.94045 -8.55424  1.000 22.59630 ? 391  MET A CB  1 
ATOM   2734 C  CG  . MET A  1 360 ? 45.50111 -16.50300 -7.12779  1.000 23.84909 ? 391  MET A CG  1 
ATOM   2735 S  SD  . MET A  1 360 ? 44.59468 -15.55362 -5.86478  1.000 26.76716 ? 391  MET A SD  1 
ATOM   2736 C  CE  . MET A  1 360 ? 42.90945 -16.05070 -6.22637  1.000 25.05254 ? 391  MET A CE  1 
ATOM   2737 N  N   . ASP A  1 361 ? 48.22511 -14.46460 -9.13823  1.000 23.84770 ? 392  ASP A N   1 
ATOM   2738 C  CA  A ASP A  1 361 ? 49.62590 -14.22938 -8.80008  0.503 25.99280 ? 392  ASP A CA  1 
ATOM   2739 C  CA  B ASP A  1 361 ? 49.63124 -14.22577 -8.81698  0.497 26.00040 ? 392  ASP A CA  1 
ATOM   2740 C  C   . ASP A  1 361 ? 49.86771 -12.76937 -8.43150  1.000 24.37337 ? 392  ASP A C   1 
ATOM   2741 O  O   . ASP A  1 361 ? 50.63333 -12.47743 -7.50562  1.000 23.95174 ? 392  ASP A O   1 
ATOM   2742 C  CB  A ASP A  1 361 ? 50.52842 -14.65435 -9.95837  0.503 26.55340 ? 392  ASP A CB  1 
ATOM   2743 C  CB  B ASP A  1 361 ? 50.51013 -14.60843 -10.00792 0.497 26.55012 ? 392  ASP A CB  1 
ATOM   2744 C  CG  A ASP A  1 361 ? 50.72227 -16.16317 -10.02633 0.503 29.72247 ? 392  ASP A CG  1 
ATOM   2745 C  CG  B ASP A  1 361 ? 51.87471 -15.12946 -9.59012  0.497 31.47594 ? 392  ASP A CG  1 
ATOM   2746 O  OD1 A ASP A  1 361 ? 50.48047 -16.85028 -9.01056  0.503 29.01061 ? 392  ASP A OD1 1 
ATOM   2747 O  OD1 B ASP A  1 361 ? 51.97894 -15.75322 -8.51189  0.497 33.58194 ? 392  ASP A OD1 1 
ATOM   2748 O  OD2 A ASP A  1 361 ? 51.12453 -16.66219 -11.09496 0.503 36.02247 ? 392  ASP A OD2 1 
ATOM   2749 O  OD2 B ASP A  1 361 ? 52.84634 -14.90980 -10.34198 0.497 36.41149 ? 392  ASP A OD2 1 
ATOM   2750 N  N   . ASP A  1 362 ? 49.21641 -11.83727 -9.13536  1.000 21.97312 ? 393  ASP A N   1 
ATOM   2751 C  CA  . ASP A  1 362 ? 49.33829 -10.42242 -8.78146  1.000 23.07267 ? 393  ASP A CA  1 
ATOM   2752 C  C   . ASP A  1 362 ? 48.77875 -10.15516 -7.39171  1.000 23.03776 ? 393  ASP A C   1 
ATOM   2753 O  O   . ASP A  1 362 ? 49.34742 -9.37154  -6.62334  1.000 23.20485 ? 393  ASP A O   1 
ATOM   2754 C  CB  . ASP A  1 362 ? 48.61792 -9.55509  -9.81450  1.000 23.56432 ? 393  ASP A CB  1 
ATOM   2755 C  CG  . ASP A  1 362 ? 49.35101 -9.49085  -11.14783 1.000 26.68701 ? 393  ASP A CG  1 
ATOM   2756 O  OD1 . ASP A  1 362 ? 50.45860 -8.91829  -11.20075 1.000 29.83456 ? 393  ASP A OD1 1 
ATOM   2757 O  OD2 . ASP A  1 362 ? 48.81865 -10.01111 -12.14551 1.000 27.41187 ? 393  ASP A OD2 1 
ATOM   2758 N  N   . VAL A  1 363 ? 47.66422 -10.80333 -7.04659  1.000 20.59516 ? 394  VAL A N   1 
ATOM   2759 C  CA  . VAL A  1 363 ? 47.09826 -10.62951 -5.71299  1.000 21.64803 ? 394  VAL A CA  1 
ATOM   2760 C  C   . VAL A  1 363 ? 48.04713 -11.17393 -4.65123  1.000 23.84512 ? 394  VAL A C   1 
ATOM   2761 O  O   . VAL A  1 363 ? 48.25254 -10.55256 -3.59948  1.000 24.86513 ? 394  VAL A O   1 
ATOM   2762 C  CB  . VAL A  1 363 ? 45.71298 -11.29893 -5.64163  1.000 22.19132 ? 394  VAL A CB  1 
ATOM   2763 C  CG1 . VAL A  1 363 ? 45.19061 -11.28768 -4.22058  1.000 24.98494 ? 394  VAL A CG1 1 
ATOM   2764 C  CG2 . VAL A  1 363 ? 44.74941 -10.59729 -6.59229  1.000 22.06146 ? 394  VAL A CG2 1 
ATOM   2765 N  N   . LEU A  1 364 ? 48.64546 -12.33509 -4.91343  1.000 22.46679 ? 395  LEU A N   1 
ATOM   2766 C  CA  . LEU A  1 364 ? 49.53069 -12.95249 -3.93457  1.000 23.49347 ? 395  LEU A CA  1 
ATOM   2767 C  C   . LEU A  1 364 ? 50.83761 -12.18163 -3.79571  1.000 25.10057 ? 395  LEU A C   1 
ATOM   2768 O  O   . LEU A  1 364 ? 51.44042 -12.18767 -2.71816  1.000 28.33390 ? 395  LEU A O   1 
ATOM   2769 C  CB  . LEU A  1 364 ? 49.80563 -14.40496 -4.32583  1.000 23.07387 ? 395  LEU A CB  1 
ATOM   2770 C  CG  . LEU A  1 364 ? 48.55706 -15.29734 -4.31700  1.000 23.17455 ? 395  LEU A CG  1 
ATOM   2771 C  CD1 . LEU A  1 364 ? 48.88347 -16.73417 -4.69478  1.000 25.78966 ? 395  LEU A CD1 1 
ATOM   2772 C  CD2 . LEU A  1 364 ? 47.86591 -15.23030 -2.95995  1.000 26.98793 ? 395  LEU A CD2 1 
ATOM   2773 N  N   . LYS A  1 365 ? 51.28555 -11.51565 -4.85898  1.000 22.98541 ? 396  LYS A N   1 
ATOM   2774 C  CA  . LYS A  1 365 ? 52.54765 -10.78340 -4.84164  1.000 25.31833 ? 396  LYS A CA  1 
ATOM   2775 C  C   . LYS A  1 365 ? 52.36368 -9.28127  -4.69477  1.000 26.40583 ? 396  LYS A C   1 
ATOM   2776 O  O   . LYS A  1 365 ? 53.36042 -8.54703  -4.68574  1.000 25.52070 ? 396  LYS A O   1 
ATOM   2777 C  CB  . LYS A  1 365 ? 53.34709 -11.07584 -6.11677  1.000 25.33264 ? 396  LYS A CB  1 
ATOM   2778 C  CG  . LYS A  1 365 ? 53.76728 -12.53001 -6.25963  1.000 30.63137 ? 396  LYS A CG  1 
ATOM   2779 C  CD  . LYS A  1 365 ? 54.35072 -12.81456 -7.63214  1.000 35.51352 ? 396  LYS A CD  1 
ATOM   2780 C  CE  . LYS A  1 365 ? 54.76231 -14.27951 -7.74873  1.000 44.36284 ? 396  LYS A CE  1 
ATOM   2781 N  NZ  . LYS A  1 365 ? 55.11094 -14.67545 -9.14953  1.000 48.44788 ? 396  LYS A NZ  1 
ATOM   2782 N  N   . ASN A  1 366 ? 51.12035 -8.81109  -4.58607  1.000 24.44415 ? 397  ASN A N   1 
ATOM   2783 C  CA  . ASN A  1 366 ? 50.80397 -7.38550  -4.52353  1.000 26.00779 ? 397  ASN A CA  1 
ATOM   2784 C  C   . ASN A  1 366 ? 51.45989 -6.61808  -5.66817  1.000 21.89941 ? 397  ASN A C   1 
ATOM   2785 O  O   . ASN A  1 366 ? 52.14338 -5.61240  -5.46879  1.000 24.92236 ? 397  ASN A O   1 
ATOM   2786 C  CB  . ASN A  1 366 ? 51.20407 -6.79057  -3.17479  1.000 28.53118 ? 397  ASN A CB  1 
ATOM   2787 C  CG  . ASN A  1 366 ? 50.61300 -5.41670  -2.95503  1.000 33.21158 ? 397  ASN A CG  1 
ATOM   2788 O  OD1 . ASN A  1 366 ? 49.46765 -5.14724  -3.34357  1.000 29.13681 ? 397  ASN A OD1 1 
ATOM   2789 N  ND2 . ASN A  1 366 ? 51.39359 -4.52806  -2.34737  1.000 30.56161 ? 397  ASN A ND2 1 
ATOM   2790 N  N   . THR A  1 367 ? 51.25459 -7.10624  -6.88442  1.000 22.19270 ? 398  THR A N   1 
ATOM   2791 C  CA  . THR A  1 367 ? 51.71912 -6.42054  -8.07782  1.000 20.97495 ? 398  THR A CA  1 
ATOM   2792 C  C   . THR A  1 367 ? 50.52183 -6.01620  -8.92778  1.000 21.09252 ? 398  THR A C   1 
ATOM   2793 O  O   . THR A  1 367 ? 49.39151 -6.46310  -8.70857  1.000 21.68986 ? 398  THR A O   1 
ATOM   2794 C  CB  . THR A  1 367 ? 52.70144 -7.29191  -8.87725  1.000 23.93335 ? 398  THR A CB  1 
ATOM   2795 O  OG1 . THR A  1 367 ? 52.10391 -8.56054  -9.16606  1.000 24.67724 ? 398  THR A OG1 1 
ATOM   2796 C  CG2 . THR A  1 367 ? 53.98170 -7.51718  -8.07728  1.000 26.79100 ? 398  THR A CG2 1 
ATOM   2797 N  N   . GLU A  1 368 ? 50.79742 -5.17664  -9.92253  1.000 20.58220 ? 399  GLU A N   1 
ATOM   2798 C  CA  . GLU A  1 368 ? 49.80871 -4.38672  -10.65068 1.000 19.70617 ? 399  GLU A CA  1 
ATOM   2799 C  C   . GLU A  1 368 ? 49.42134 -5.07183  -11.96083 1.000 20.77066 ? 399  GLU A C   1 
ATOM   2800 O  O   . GLU A  1 368 ? 50.15191 -4.94903  -12.95658 1.000 20.73191 ? 399  GLU A O   1 
ATOM   2801 C  CB  . GLU A  1 368 ? 50.38262 -2.99087  -10.92188 1.000 19.69764 ? 399  GLU A CB  1 
ATOM   2802 C  CG  . GLU A  1 368 ? 49.44199 -2.03302  -11.62856 1.000 20.06923 ? 399  GLU A CG  1 
ATOM   2803 C  CD  . GLU A  1 368 ? 50.02757 -0.63144  -11.80018 1.000 23.68548 ? 399  GLU A CD  1 
ATOM   2804 O  OE1 . GLU A  1 368 ? 51.22796 -0.40773  -11.48519 1.000 22.27254 ? 399  GLU A OE1 1 
ATOM   2805 O  OE2 . GLU A  1 368 ? 49.27645 0.25127   -12.25581 1.000 23.44282 ? 399  GLU A OE2 1 
ATOM   2806 N  N   . PRO A  1 369 ? 48.28121 -5.77038  -12.03280 1.000 19.94085 ? 400  PRO A N   1 
ATOM   2807 C  CA  . PRO A  1 369 ? 47.97758 -6.52825  -13.25680 1.000 20.60531 ? 400  PRO A CA  1 
ATOM   2808 C  C   . PRO A  1 369 ? 47.70254 -5.65499  -14.46831 1.000 19.21913 ? 400  PRO A C   1 
ATOM   2809 O  O   . PRO A  1 369 ? 48.05105 -6.05471  -15.58703 1.000 21.58888 ? 400  PRO A O   1 
ATOM   2810 C  CB  . PRO A  1 369 ? 46.74134 -7.35448  -12.86493 1.000 20.46241 ? 400  PRO A CB  1 
ATOM   2811 C  CG  . PRO A  1 369 ? 46.12169 -6.59455  -11.73995 1.000 19.73999 ? 400  PRO A CG  1 
ATOM   2812 C  CD  . PRO A  1 369 ? 47.28170 -6.00943  -10.97568 1.000 17.91942 ? 400  PRO A CD  1 
ATOM   2813 N  N   . TYR A  1 370 ? 47.09696 -4.47868  -14.29022 1.000 17.77154 ? 401  TYR A N   1 
ATOM   2814 C  CA  . TYR A  1 370 ? 46.75824 -3.59993  -15.40441 1.000 18.00153 ? 401  TYR A CA  1 
ATOM   2815 C  C   . TYR A  1 370 ? 47.74818 -2.45254  -15.56923 1.000 18.78983 ? 401  TYR A C   1 
ATOM   2816 O  O   . TYR A  1 370 ? 47.38025 -1.38613  -16.06622 1.000 20.45729 ? 401  TYR A O   1 
ATOM   2817 C  CB  . TYR A  1 370 ? 45.33434 -3.05953  -15.24248 1.000 17.04134 ? 401  TYR A CB  1 
ATOM   2818 C  CG  . TYR A  1 370 ? 44.29328 -4.11424  -15.56648 1.000 18.33707 ? 401  TYR A CG  1 
ATOM   2819 C  CD1 . TYR A  1 370 ? 43.84217 -5.00683  -14.60068 1.000 20.01272 ? 401  TYR A CD1 1 
ATOM   2820 C  CD2 . TYR A  1 370 ? 43.79761 -4.23824  -16.85425 1.000 20.27032 ? 401  TYR A CD2 1 
ATOM   2821 C  CE1 . TYR A  1 370 ? 42.89879 -5.98803  -14.91484 1.000 19.35963 ? 401  TYR A CE1 1 
ATOM   2822 C  CE2 . TYR A  1 370 ? 42.86942 -5.21129  -17.17650 1.000 18.50427 ? 401  TYR A CE2 1 
ATOM   2823 C  CZ  . TYR A  1 370 ? 42.42271 -6.07572  -16.21142 1.000 19.23083 ? 401  TYR A CZ  1 
ATOM   2824 O  OH  . TYR A  1 370 ? 41.49453 -7.03399  -16.54759 1.000 19.92391 ? 401  TYR A OH  1 
ATOM   2825 N  N   . LYS A  1 371 ? 48.99982 -2.65633  -15.16436 1.000 19.55732 ? 402  LYS A N   1 
ATOM   2826 C  CA  . LYS A  1 371 ? 50.02139 -1.63955  -15.36548 1.000 22.58111 ? 402  LYS A CA  1 
ATOM   2827 C  C   . LYS A  1 371 ? 50.07910 -1.24808  -16.83436 1.000 22.80149 ? 402  LYS A C   1 
ATOM   2828 O  O   . LYS A  1 371 ? 50.21623 -2.10876  -17.70885 1.000 25.19409 ? 402  LYS A O   1 
ATOM   2829 C  CB  . LYS A  1 371 ? 51.38562 -2.15425  -14.89797 1.000 24.68615 ? 402  LYS A CB  1 
ATOM   2830 C  CG  . LYS A  1 371 ? 52.46281 -1.07489  -14.92424 1.000 28.26474 ? 402  LYS A CG  1 
ATOM   2831 C  CD  . LYS A  1 371 ? 53.86223 -1.65853  -14.95982 1.000 38.96656 ? 402  LYS A CD  1 
ATOM   2832 C  CE  . LYS A  1 371 ? 54.34387 -2.06873  -13.58569 1.000 43.21134 ? 402  LYS A CE  1 
ATOM   2833 N  NZ  . LYS A  1 371 ? 55.84259 -2.13583  -13.55292 1.000 52.98945 ? 402  LYS A NZ  1 
ATOM   2834 N  N   . ASP A  1 372 ? 49.94353 0.05115   -17.09416 1.000 22.29315 ? 403  ASP A N   1 
ATOM   2835 C  CA  . ASP A  1 372 ? 49.95910 0.62121   -18.44079 1.000 24.68205 ? 403  ASP A CA  1 
ATOM   2836 C  C   . ASP A  1 372 ? 48.86794 0.04955   -19.34677 1.000 27.38207 ? 403  ASP A C   1 
ATOM   2837 O  O   . ASP A  1 372 ? 49.00824 0.06603   -20.57909 1.000 26.82923 ? 403  ASP A O   1 
ATOM   2838 C  CB  . ASP A  1 372 ? 51.33596 0.44069   -19.09503 1.000 27.49967 ? 403  ASP A CB  1 
ATOM   2839 C  CG  . ASP A  1 372 ? 52.43543 1.13121   -18.31670 1.000 34.75668 ? 403  ASP A CG  1 
ATOM   2840 O  OD1 . ASP A  1 372 ? 52.17431 2.22447   -17.77675 1.000 37.99003 ? 403  ASP A OD1 1 
ATOM   2841 O  OD2 . ASP A  1 372 ? 53.54678 0.57236   -18.23121 1.000 41.03128 ? 403  ASP A OD2 1 
ATOM   2842 N  N   . GLU A  1 373 ? 47.76504 -0.43677  -18.77255 1.000 24.28508 ? 404  GLU A N   1 
ATOM   2843 C  CA  . GLU A  1 373 ? 46.63847 -0.93525  -19.55217 1.000 20.87399 ? 404  GLU A CA  1 
ATOM   2844 C  C   . GLU A  1 373 ? 45.33900 -0.35436  -19.00922 1.000 20.31793 ? 404  GLU A C   1 
ATOM   2845 O  O   . GLU A  1 373 ? 45.29009 0.18152   -17.89971 1.000 22.97908 ? 404  GLU A O   1 
ATOM   2846 C  CB  . GLU A  1 373 ? 46.55993 -2.46719  -19.55070 1.000 22.38462 ? 404  GLU A CB  1 
ATOM   2847 C  CG  . GLU A  1 373 ? 47.76660 -3.14470  -20.18113 1.000 25.19162 ? 404  GLU A CG  1 
ATOM   2848 C  CD  . GLU A  1 373 ? 47.63134 -4.65632  -20.21070 1.000 32.37398 ? 404  GLU A CD  1 
ATOM   2849 O  OE1 . GLU A  1 373 ? 46.50088 -5.14591  -20.39466 1.000 33.78870 ? 404  GLU A OE1 1 
ATOM   2850 O  OE2 . GLU A  1 373 ? 48.65591 -5.35060  -20.04529 1.000 42.39508 ? 404  GLU A OE2 1 
ATOM   2851 N  N   . MET A  1 374 ? 44.28787 -0.46663  -19.81389 1.000 20.09967 ? 405  MET A N   1 
ATOM   2852 C  CA  . MET A  1 374 ? 43.02724 0.22229   -19.56975 1.000 18.37942 ? 405  MET A CA  1 
ATOM   2853 C  C   . MET A  1 374 ? 41.97437 -0.70038  -18.96646 1.000 18.43163 ? 405  MET A C   1 
ATOM   2854 O  O   . MET A  1 374 ? 41.87386 -1.87942  -19.31069 1.000 19.67259 ? 405  MET A O   1 
ATOM   2855 C  CB  . MET A  1 374 ? 42.46354 0.79213   -20.86768 1.000 22.20953 ? 405  MET A CB  1 
ATOM   2856 C  CG  . MET A  1 374 ? 43.18084 2.00334   -21.38491 1.000 25.19989 ? 405  MET A CG  1 
ATOM   2857 S  SD  . MET A  1 374 ? 42.69750 3.47034   -20.46444 1.000 26.77363 ? 405  MET A SD  1 
ATOM   2858 C  CE  . MET A  1 374 ? 42.77380 4.67847   -21.78002 1.000 25.76641 ? 405  MET A CE  1 
ATOM   2859 N  N   . ILE A  1 375 ? 41.15524 -0.11634  -18.09622 1.000 17.31067 ? 406  ILE A N   1 
ATOM   2860 C  CA  . ILE A  1 375 ? 39.86791 -0.66744  -17.69640 1.000 17.76494 ? 406  ILE A CA  1 
ATOM   2861 C  C   . ILE A  1 375 ? 38.81570 0.35168   -18.10043 1.000 16.41097 ? 406  ILE A C   1 
ATOM   2862 O  O   . ILE A  1 375 ? 38.96848 1.54941   -17.81730 1.000 17.64128 ? 406  ILE A O   1 
ATOM   2863 C  CB  . ILE A  1 375 ? 39.83185 -0.96520  -16.18805 1.000 18.82497 ? 406  ILE A CB  1 
ATOM   2864 C  CG1 . ILE A  1 375 ? 40.70096 -2.19781  -15.90507 1.000 19.45913 ? 406  ILE A CG1 1 
ATOM   2865 C  CG2 . ILE A  1 375 ? 38.39079 -1.15829  -15.69188 1.000 20.25288 ? 406  ILE A CG2 1 
ATOM   2866 C  CD1 . ILE A  1 375 ? 40.91840 -2.49511  -14.40883 1.000 20.30780 ? 406  ILE A CD1 1 
ATOM   2867 N  N   . TYR A  1 376 ? 37.77280 -0.12077  -18.78703 1.000 15.67262 ? 407  TYR A N   1 
ATOM   2868 C  CA  . TYR A  1 376 ? 36.84572 0.70598   -19.54332 1.000 18.51043 ? 407  TYR A CA  1 
ATOM   2869 C  C   . TYR A  1 376 ? 35.40408 0.53610   -19.09906 1.000 16.97413 ? 407  TYR A C   1 
ATOM   2870 O  O   . TYR A  1 376 ? 35.00551 -0.52072  -18.60182 1.000 18.57302 ? 407  TYR A O   1 
ATOM   2871 C  CB  . TYR A  1 376 ? 36.82969 0.32291   -21.01497 1.000 20.94782 ? 407  TYR A CB  1 
ATOM   2872 C  CG  . TYR A  1 376 ? 38.09067 0.44084   -21.79335 1.000 21.91168 ? 407  TYR A CG  1 
ATOM   2873 C  CD1 . TYR A  1 376 ? 38.60420 1.69010   -22.10660 1.000 21.16335 ? 407  TYR A CD1 1 
ATOM   2874 C  CD2 . TYR A  1 376 ? 38.71446 -0.69300  -22.30931 1.000 24.30251 ? 407  TYR A CD2 1 
ATOM   2875 C  CE1 . TYR A  1 376 ? 39.73219 1.82187   -22.87162 1.000 25.70657 ? 407  TYR A CE1 1 
ATOM   2876 C  CE2 . TYR A  1 376 ? 39.85656 -0.57267  -23.08186 1.000 23.51830 ? 407  TYR A CE2 1 
ATOM   2877 C  CZ  . TYR A  1 376 ? 40.35092 0.69459   -23.36199 1.000 24.86562 ? 407  TYR A CZ  1 
ATOM   2878 O  OH  . TYR A  1 376 ? 41.49140 0.84237   -24.12667 1.000 30.53349 ? 407  TYR A OH  1 
ATOM   2879 N  N   . SER A  1 377 ? 34.60296 1.55381   -19.41421 1.000 16.32018 ? 408  SER A N   1 
ATOM   2880 C  CA  . SER A  1 377 ? 33.15303 1.41499   -19.44218 1.000 18.00899 ? 408  SER A CA  1 
ATOM   2881 C  C   . SER A  1 377 ? 32.59226 2.32084   -20.52657 1.000 15.30096 ? 408  SER A C   1 
ATOM   2882 O  O   . SER A  1 377 ? 33.05852 3.44839   -20.71980 1.000 16.49051 ? 408  SER A O   1 
ATOM   2883 C  CB  . SER A  1 377 ? 32.49782 1.76301   -18.09834 1.000 18.03625 ? 408  SER A CB  1 
ATOM   2884 O  OG  . SER A  1 377 ? 31.08206 1.63380   -18.21040 1.000 20.64537 ? 408  SER A OG  1 
ATOM   2885 N  N   . LEU A  1 378 ? 31.59797 1.81621   -21.24593 1.000 16.94011 ? 409  LEU A N   1 
ATOM   2886 C  CA  . LEU A  1 378 ? 30.85172 2.64811   -22.17654 1.000 14.77022 ? 409  LEU A CA  1 
ATOM   2887 C  C   . LEU A  1 378 ? 29.39153 2.28427   -22.01381 1.000 15.65184 ? 409  LEU A C   1 
ATOM   2888 O  O   . LEU A  1 378 ? 29.02931 1.11141   -22.14649 1.000 15.80734 ? 409  LEU A O   1 
ATOM   2889 C  CB  . LEU A  1 378 ? 31.31708 2.45140   -23.63294 1.000 16.84868 ? 409  LEU A CB  1 
ATOM   2890 C  CG  . LEU A  1 378 ? 30.64621 3.39676   -24.63927 1.000 17.44277 ? 409  LEU A CG  1 
ATOM   2891 C  CD1 . LEU A  1 378 ? 31.60266 3.80959   -25.78047 1.000 18.93344 ? 409  LEU A CD1 1 
ATOM   2892 C  CD2 . LEU A  1 378 ? 29.36969 2.78773   -25.21583 1.000 18.27009 ? 409  LEU A CD2 1 
ATOM   2893 N  N   . ARG A  1 379 ? 28.55891 3.28348   -21.72103 1.000 13.63749 ? 410  ARG A N   1 
ATOM   2894 C  CA  . ARG A  1 379 ? 27.14559 3.04595   -21.48080 1.000 15.56779 ? 410  ARG A CA  1 
ATOM   2895 C  C   . ARG A  1 379 ? 26.33173 3.83724   -22.49604 1.000 16.40326 ? 410  ARG A C   1 
ATOM   2896 O  O   . ARG A  1 379 ? 26.46590 5.06327   -22.59931 1.000 17.11002 ? 410  ARG A O   1 
ATOM   2897 C  CB  . ARG A  1 379 ? 26.77786 3.41123   -20.03709 1.000 16.16097 ? 410  ARG A CB  1 
ATOM   2898 C  CG  . ARG A  1 379 ? 25.31042 3.14310   -19.69352 1.000 15.02290 ? 410  ARG A CG  1 
ATOM   2899 C  CD  . ARG A  1 379 ? 24.50222 4.43594   -19.71893 1.000 15.98668 ? 410  ARG A CD  1 
ATOM   2900 N  NE  . ARG A  1 379 ? 23.06725 4.20219   -19.85801 1.000 16.70573 ? 410  ARG A NE  1 
ATOM   2901 C  CZ  . ARG A  1 379 ? 22.26909 3.86817   -18.85286 1.000 18.98990 ? 410  ARG A CZ  1 
ATOM   2902 N  NH1 . ARG A  1 379 ? 22.73719 3.71071   -17.62110 1.000 17.80458 ? 410  ARG A NH1 1 
ATOM   2903 N  NH2 . ARG A  1 379 ? 20.97086 3.67924   -19.08867 1.000 17.96735 ? 410  ARG A NH2 1 
ATOM   2904 N  N   . TYR A  1 380 ? 25.49090 3.12834   -23.24602 1.000 16.36346 ? 411  TYR A N   1 
ATOM   2905 C  CA  . TYR A  1 380 ? 24.68427 3.76629   -24.27948 1.000 17.45354 ? 411  TYR A CA  1 
ATOM   2906 C  C   . TYR A  1 380 ? 23.58315 4.61595   -23.66025 1.000 17.60485 ? 411  TYR A C   1 
ATOM   2907 O  O   . TYR A  1 380 ? 22.86119 4.16217   -22.76769 1.000 18.92752 ? 411  TYR A O   1 
ATOM   2908 C  CB  . TYR A  1 380 ? 24.07102 2.69997   -25.18406 1.000 16.08046 ? 411  TYR A CB  1 
ATOM   2909 C  CG  . TYR A  1 380 ? 25.08981 1.86346   -25.93431 1.000 17.16416 ? 411  TYR A CG  1 
ATOM   2910 C  CD1 . TYR A  1 380 ? 25.95259 2.45115   -26.85261 1.000 19.88903 ? 411  TYR A CD1 1 
ATOM   2911 C  CD2 . TYR A  1 380 ? 25.17288 0.49263   -25.74645 1.000 17.78404 ? 411  TYR A CD2 1 
ATOM   2912 C  CE1 . TYR A  1 380 ? 26.89064 1.68975   -27.54643 1.000 18.48272 ? 411  TYR A CE1 1 
ATOM   2913 C  CE2 . TYR A  1 380 ? 26.10876 -0.27766  -26.44456 1.000 18.61061 ? 411  TYR A CE2 1 
ATOM   2914 C  CZ  . TYR A  1 380 ? 26.96079 0.33205   -27.33010 1.000 19.47408 ? 411  TYR A CZ  1 
ATOM   2915 O  OH  . TYR A  1 380 ? 27.87959 -0.43150  -28.01553 1.000 20.59025 ? 411  TYR A OH  1 
ATOM   2916 N  N   . ARG A  1 381 ? 23.43343 5.83938   -24.15091 1.000 15.97060 ? 412  ARG A N   1 
ATOM   2917 C  CA  . ARG A  1 381 ? 22.36201 6.73679   -23.72578 1.000 17.76531 ? 412  ARG A CA  1 
ATOM   2918 C  C   . ARG A  1 381 ? 21.45151 7.01480   -24.91859 1.000 18.32943 ? 412  ARG A C   1 
ATOM   2919 O  O   . ARG A  1 381 ? 21.61293 6.43292   -25.98940 1.000 17.89726 ? 412  ARG A O   1 
ATOM   2920 C  CB  . ARG A  1 381 ? 22.93468 8.03175   -23.14732 1.000 17.78582 ? 412  ARG A CB  1 
ATOM   2921 C  CG  . ARG A  1 381 ? 23.67533 7.86392   -21.81467 1.000 16.44131 ? 412  ARG A CG  1 
ATOM   2922 C  CD  . ARG A  1 381 ? 22.70016 7.60084   -20.64678 1.000 15.65881 ? 412  ARG A CD  1 
ATOM   2923 N  NE  . ARG A  1 381 ? 23.41328 7.46682   -19.37512 1.000 16.46026 ? 412  ARG A NE  1 
ATOM   2924 C  CZ  . ARG A  1 381 ? 22.82073 7.19224   -18.22071 1.000 20.14311 ? 412  ARG A CZ  1 
ATOM   2925 N  NH1 . ARG A  1 381 ? 21.51554 7.00067   -18.14478 1.000 18.52856 ? 412  ARG A NH1 1 
ATOM   2926 N  NH2 . ARG A  1 381 ? 23.56073 7.09476   -17.11630 1.000 18.26531 ? 412  ARG A NH2 1 
ATOM   2927 N  N   . GLU A  1 382 ? 20.48961 7.91935   -24.73623 1.000 19.43257 ? 413  GLU A N   1 
ATOM   2928 C  CA  . GLU A  1 382 ? 19.53704 8.21192   -25.80730 1.000 16.58154 ? 413  GLU A CA  1 
ATOM   2929 C  C   . GLU A  1 382 ? 20.15169 9.25619   -26.73479 1.000 17.57369 ? 413  GLU A C   1 
ATOM   2930 O  O   . GLU A  1 382 ? 19.83439 10.44068  -26.68562 1.000 20.67918 ? 413  GLU A O   1 
ATOM   2931 C  CB  . GLU A  1 382 ? 18.20388 8.67284   -25.23764 1.000 18.29402 ? 413  GLU A CB  1 
ATOM   2932 C  CG  . GLU A  1 382 ? 17.58089 7.69451   -24.23467 1.000 22.62875 ? 413  GLU A CG  1 
ATOM   2933 C  CD  . GLU A  1 382 ? 17.67850 6.24882   -24.68644 1.000 25.56812 ? 413  GLU A CD  1 
ATOM   2934 O  OE1 . GLU A  1 382 ? 17.25151 5.95419   -25.82625 1.000 24.77552 ? 413  GLU A OE1 1 
ATOM   2935 O  OE2 . GLU A  1 382 ? 18.20157 5.41054   -23.91695 1.000 25.65850 ? 413  GLU A OE2 1 
ATOM   2936 N  N   . GLY A  1 383 ? 21.05493 8.79260   -27.59649 1.000 18.36158 ? 414  GLY A N   1 
ATOM   2937 C  CA  . GLY A  1 383 ? 21.65143 9.63064   -28.62113 1.000 19.41921 ? 414  GLY A CA  1 
ATOM   2938 C  C   . GLY A  1 383 ? 23.10422 9.98876   -28.40881 1.000 19.19645 ? 414  GLY A C   1 
ATOM   2939 O  O   . GLY A  1 383 ? 23.65425 10.75599  -29.20723 1.000 23.22994 ? 414  GLY A O   1 
ATOM   2940 N  N   . TYR A  1 384 ? 23.73684 9.49097   -27.35220 1.000 16.47513 ? 415  TYR A N   1 
ATOM   2941 C  CA  . TYR A  1 384 ? 25.15346 9.72366   -27.08306 1.000 15.73498 ? 415  TYR A CA  1 
ATOM   2942 C  C   . TYR A  1 384 ? 25.61779 8.59066   -26.17410 1.000 16.20926 ? 415  TYR A C   1 
ATOM   2943 O  O   . TYR A  1 384 ? 24.82277 7.73222   -25.78590 1.000 17.13155 ? 415  TYR A O   1 
ATOM   2944 C  CB  . TYR A  1 384 ? 25.38333 11.10288  -26.44673 1.000 15.55455 ? 415  TYR A CB  1 
ATOM   2945 C  CG  . TYR A  1 384 ? 24.74907 11.21945  -25.06519 1.000 18.01517 ? 415  TYR A CG  1 
ATOM   2946 C  CD1 . TYR A  1 384 ? 23.41694 11.57642  -24.91679 1.000 19.45331 ? 415  TYR A CD1 1 
ATOM   2947 C  CD2 . TYR A  1 384 ? 25.48729 10.94645  -23.91948 1.000 16.96496 ? 415  TYR A CD2 1 
ATOM   2948 C  CE1 . TYR A  1 384 ? 22.83149 11.67204  -23.65101 1.000 17.43084 ? 415  TYR A CE1 1 
ATOM   2949 C  CE2 . TYR A  1 384 ? 24.91276 11.04458  -22.66109 1.000 16.96950 ? 415  TYR A CE2 1 
ATOM   2950 C  CZ  . TYR A  1 384 ? 23.59837 11.39899  -22.53586 1.000 17.43962 ? 415  TYR A CZ  1 
ATOM   2951 O  OH  . TYR A  1 384 ? 23.03583 11.47881  -21.27546 1.000 17.61986 ? 415  TYR A OH  1 
ATOM   2952 N  N   . ASN A  1 385 ? 26.90544 8.58589   -25.83468 1.000 17.31033 ? 416  ASN A N   1 
ATOM   2953 C  CA  . ASN A  1 385 ? 27.47866 7.55302   -24.97733 1.000 15.50869 ? 416  ASN A CA  1 
ATOM   2954 C  C   . ASN A  1 385 ? 28.15927 8.17356   -23.76895 1.000 16.09485 ? 416  ASN A C   1 
ATOM   2955 O  O   . ASN A  1 385 ? 28.88291 9.15961   -23.90197 1.000 17.38263 ? 416  ASN A O   1 
ATOM   2956 C  CB  . ASN A  1 385 ? 28.50953 6.72799   -25.73125 1.000 16.91802 ? 416  ASN A CB  1 
ATOM   2957 C  CG  . ASN A  1 385 ? 27.92518 6.07633   -26.95359 1.000 16.94763 ? 416  ASN A CG  1 
ATOM   2958 O  OD1 . ASN A  1 385 ? 26.90592 5.40278   -26.86576 1.000 19.11078 ? 416  ASN A OD1 1 
ATOM   2959 N  ND2 . ASN A  1 385 ? 28.54745 6.30890   -28.11535 1.000 19.50238 ? 416  ASN A ND2 1 
ATOM   2960 N  N   . ASP A  1 386 ? 27.95327 7.55761   -22.59959 1.000 16.00249 ? 417  ASP A N   1 
ATOM   2961 C  CA  . ASP A  1 386 ? 28.76415 7.84039   -21.42079 1.000 15.44038 ? 417  ASP A CA  1 
ATOM   2962 C  C   . ASP A  1 386 ? 29.98194 6.92682   -21.43858 1.000 14.13458 ? 417  ASP A C   1 
ATOM   2963 O  O   . ASP A  1 386 ? 29.87778 5.75266   -21.79210 1.000 16.03780 ? 417  ASP A O   1 
ATOM   2964 C  CB  . ASP A  1 386 ? 27.95933 7.60978   -20.13272 1.000 15.92160 ? 417  ASP A CB  1 
ATOM   2965 C  CG  . ASP A  1 386 ? 26.90239 8.67796   -19.89780 1.000 16.95259 ? 417  ASP A CG  1 
ATOM   2966 O  OD1 . ASP A  1 386 ? 27.04711 9.80238   -20.41695 1.000 15.92912 ? 417  ASP A OD1 1 
ATOM   2967 O  OD2 . ASP A  1 386 ? 25.93217 8.39614   -19.15230 1.000 17.35111 ? 417  ASP A OD2 1 
ATOM   2968 N  N   . VAL A  1 387 ? 31.14737 7.47050   -21.07120 1.000 15.04273 ? 418  VAL A N   1 
ATOM   2969 C  CA  . VAL A  1 387 ? 32.38934 6.71231   -21.12961 1.000 14.11382 ? 418  VAL A CA  1 
ATOM   2970 C  C   . VAL A  1 387 ? 33.19309 6.91585   -19.85642 1.000 14.89913 ? 418  VAL A C   1 
ATOM   2971 O  O   . VAL A  1 387 ? 33.18577 7.99632   -19.25576 1.000 16.41370 ? 418  VAL A O   1 
ATOM   2972 C  CB  . VAL A  1 387 ? 33.24171 7.11200   -22.35587 1.000 14.68227 ? 418  VAL A CB  1 
ATOM   2973 C  CG1 . VAL A  1 387 ? 34.46636 6.21653   -22.47444 1.000 17.74330 ? 418  VAL A CG1 1 
ATOM   2974 C  CG2 . VAL A  1 387 ? 32.40673 7.03850   -23.62887 1.000 18.42579 ? 418  VAL A CG2 1 
ATOM   2975 N  N   . GLY A  1 388 ? 33.91542 5.86898   -19.46972 1.000 15.54804 ? 419  GLY A N   1 
ATOM   2976 C  CA  . GLY A  1 388 ? 34.96698 5.97653   -18.47195 1.000 16.71205 ? 419  GLY A CA  1 
ATOM   2977 C  C   . GLY A  1 388 ? 36.13135 5.09998   -18.89298 1.000 14.69682 ? 419  GLY A C   1 
ATOM   2978 O  O   . GLY A  1 388 ? 35.92360 4.01523   -19.44657 1.000 17.54063 ? 419  GLY A O   1 
ATOM   2979 N  N   . ALA A  1 389 ? 37.36419 5.54747   -18.64813 1.000 15.89719 ? 420  ALA A N   1 
ATOM   2980 C  CA  . ALA A  1 389 ? 38.52963 4.73418   -18.96970 1.000 17.22840 ? 420  ALA A CA  1 
ATOM   2981 C  C   . ALA A  1 389 ? 39.63734 5.07183   -17.98965 1.000 18.09469 ? 420  ALA A C   1 
ATOM   2982 O  O   . ALA A  1 389 ? 39.97473 6.24870   -17.82384 1.000 19.75118 ? 420  ALA A O   1 
ATOM   2983 C  CB  . ALA A  1 389 ? 38.99155 4.97584   -20.41635 1.000 19.62422 ? 420  ALA A CB  1 
ATOM   2984 N  N   . ARG A  1 390 ? 40.19134 4.05088   -17.34259 1.000 15.16269 ? 421  ARG A N   1 
ATOM   2985 C  CA  . ARG A  1 390 ? 41.21566 4.24825   -16.32781 1.000 17.34227 ? 421  ARG A CA  1 
ATOM   2986 C  C   . ARG A  1 390 ? 42.50859 3.53237   -16.69714 1.000 18.39665 ? 421  ARG A C   1 
ATOM   2987 O  O   . ARG A  1 390 ? 42.49253 2.35330   -17.06292 1.000 18.05979 ? 421  ARG A O   1 
ATOM   2988 C  CB  . ARG A  1 390 ? 40.74632 3.73570   -14.96550 1.000 15.54779 ? 421  ARG A CB  1 
ATOM   2989 C  CG  . ARG A  1 390 ? 41.84908 3.89402   -13.91427 1.000 18.12626 ? 421  ARG A CG  1 
ATOM   2990 C  CD  . ARG A  1 390 ? 41.37673 3.52562   -12.50913 1.000 18.09223 ? 421  ARG A CD  1 
ATOM   2991 N  NE  . ARG A  1 390 ? 42.49519 3.62252   -11.57619 1.000 17.65318 ? 421  ARG A NE  1 
ATOM   2992 C  CZ  . ARG A  1 390 ? 42.41208 3.42096   -10.26730 1.000 21.23169 ? 421  ARG A CZ  1 
ATOM   2993 N  NH1 . ARG A  1 390 ? 41.25087 3.20710   -9.67428  1.000 16.13892 ? 421  ARG A NH1 1 
ATOM   2994 N  NH2 . ARG A  1 390 ? 43.52623 3.45074   -9.53145  1.000 17.85792 ? 421  ARG A NH2 1 
ATOM   2995 N  N   . MET A  1 391 ? 43.62952 4.23987   -16.55840 1.000 18.23887 ? 422  MET A N   1 
ATOM   2996 C  CA  A MET A  1 391 ? 44.95986 3.64997   -16.65536 0.542 18.31118 ? 422  MET A CA  1 
ATOM   2997 C  CA  B MET A  1 391 ? 44.95109 3.62932   -16.63747 0.458 18.32771 ? 422  MET A CA  1 
ATOM   2998 C  C   . MET A  1 391 ? 45.77260 4.17858   -15.48657 1.000 18.25306 ? 422  MET A C   1 
ATOM   2999 O  O   . MET A  1 391 ? 45.98063 5.39381   -15.39017 1.000 19.83810 ? 422  MET A O   1 
ATOM   3000 C  CB  A MET A  1 391 ? 45.62636 4.01144   -17.98330 0.542 21.81152 ? 422  MET A CB  1 
ATOM   3001 C  CB  B MET A  1 391 ? 45.64668 3.89831   -17.97450 0.458 21.85024 ? 422  MET A CB  1 
ATOM   3002 C  CG  A MET A  1 391 ? 47.06558 3.55980   -18.09150 0.542 21.54496 ? 422  MET A CG  1 
ATOM   3003 C  CG  B MET A  1 391 ? 46.97389 3.14911   -18.08440 0.458 20.51037 ? 422  MET A CG  1 
ATOM   3004 S  SD  A MET A  1 391 ? 47.74412 3.97795   -19.70373 0.542 29.11275 ? 422  MET A SD  1 
ATOM   3005 S  SD  B MET A  1 391 ? 47.75187 3.16804   -19.70966 0.458 25.10415 ? 422  MET A SD  1 
ATOM   3006 C  CE  A MET A  1 391 ? 46.76945 2.87867   -20.74042 0.542 19.80050 ? 422  MET A CE  1 
ATOM   3007 C  CE  B MET A  1 391 ? 47.30898 4.81180   -20.27561 0.458 22.01063 ? 422  MET A CE  1 
ATOM   3008 N  N   . GLY A  1 392 ? 46.20685 3.28325   -14.59971 1.000 19.56130 ? 423  GLY A N   1 
ATOM   3009 C  CA  . GLY A  1 392 ? 46.98580 3.72642   -13.45225 1.000 20.55684 ? 423  GLY A CA  1 
ATOM   3010 C  C   . GLY A  1 392 ? 46.18878 4.69676   -12.59506 1.000 19.83213 ? 423  GLY A C   1 
ATOM   3011 O  O   . GLY A  1 392 ? 45.02285 4.45604   -12.26255 1.000 20.41840 ? 423  GLY A O   1 
ATOM   3012 N  N   . ASP A  1 393 ? 46.81786 5.81210   -12.22532 1.000 17.83439 ? 424  ASP A N   1 
ATOM   3013 C  CA  . ASP A  1 393 ? 46.15447 6.81718   -11.39920 1.000 19.41897 ? 424  ASP A CA  1 
ATOM   3014 C  C   . ASP A  1 393 ? 45.19410 7.71088   -12.17167 1.000 19.25364 ? 424  ASP A C   1 
ATOM   3015 O  O   . ASP A  1 393 ? 44.59838 8.60786   -11.56067 1.000 19.60037 ? 424  ASP A O   1 
ATOM   3016 C  CB  . ASP A  1 393 ? 47.17896 7.72677   -10.72006 1.000 19.23002 ? 424  ASP A CB  1 
ATOM   3017 C  CG  . ASP A  1 393 ? 47.90999 7.05272   -9.57375  1.000 27.82701 ? 424  ASP A CG  1 
ATOM   3018 O  OD1 . ASP A  1 393 ? 47.40757 6.06281   -9.01545  1.000 22.05500 ? 424  ASP A OD1 1 
ATOM   3019 O  OD2 . ASP A  1 393 ? 48.99115 7.55533   -9.20272  1.000 37.44703 ? 424  ASP A OD2 1 
ATOM   3020 N  N   . TRP A  1 394 ? 45.05098 7.53019   -13.48125 1.000 18.10775 ? 425  TRP A N   1 
ATOM   3021 C  CA  . TRP A  1 394 ? 44.36698 8.50229   -14.32614 1.000 17.72251 ? 425  TRP A CA  1 
ATOM   3022 C  C   . TRP A  1 394 ? 43.08868 7.92346   -14.91350 1.000 19.91789 ? 425  TRP A C   1 
ATOM   3023 O  O   . TRP A  1 394 ? 43.03224 6.74245   -15.27591 1.000 19.08402 ? 425  TRP A O   1 
ATOM   3024 C  CB  . TRP A  1 394 ? 45.29337 8.99133   -15.44551 1.000 19.55474 ? 425  TRP A CB  1 
ATOM   3025 C  CG  . TRP A  1 394 ? 46.44377 9.75930   -14.88159 1.000 19.07128 ? 425  TRP A CG  1 
ATOM   3026 C  CD1 . TRP A  1 394 ? 47.68326 9.27909   -14.56913 1.000 25.08796 ? 425  TRP A CD1 1 
ATOM   3027 C  CD2 . TRP A  1 394 ? 46.44842 11.14749  -14.52770 1.000 20.71498 ? 425  TRP A CD2 1 
ATOM   3028 N  NE1 . TRP A  1 394 ? 48.46403 10.28931  -14.04590 1.000 25.25743 ? 425  TRP A NE1 1 
ATOM   3029 C  CE2 . TRP A  1 394 ? 47.73159 11.44652  -14.01543 1.000 23.03447 ? 425  TRP A CE2 1 
ATOM   3030 C  CE3 . TRP A  1 394 ? 45.49801 12.16808  -14.60407 1.000 21.50611 ? 425  TRP A CE3 1 
ATOM   3031 C  CZ2 . TRP A  1 394 ? 48.07896 12.72368  -13.57396 1.000 25.43534 ? 425  TRP A CZ2 1 
ATOM   3032 C  CZ3 . TRP A  1 394 ? 45.84535 13.43631  -14.16468 1.000 23.63327 ? 425  TRP A CZ3 1 
ATOM   3033 C  CH2 . TRP A  1 394 ? 47.12661 13.70257  -13.65997 1.000 24.71370 ? 425  TRP A CH2 1 
ATOM   3034 N  N   . LYS A  1 395 ? 42.06840 8.77197   -15.00771 1.000 18.03430 ? 426  LYS A N   1 
ATOM   3035 C  CA  . LYS A  1 395 ? 40.79458 8.38556   -15.59324 1.000 17.65502 ? 426  LYS A CA  1 
ATOM   3036 C  C   . LYS A  1 395 ? 40.27565 9.49674   -16.49106 1.000 17.65106 ? 426  LYS A C   1 
ATOM   3037 O  O   . LYS A  1 395 ? 40.34225 10.67539  -16.13260 1.000 19.60804 ? 426  LYS A O   1 
ATOM   3038 C  CB  . LYS A  1 395 ? 39.74966 8.09083   -14.51552 1.000 17.19040 ? 426  LYS A CB  1 
ATOM   3039 C  CG  . LYS A  1 395 ? 38.45962 7.57368   -15.14083 1.000 19.76822 ? 426  LYS A CG  1 
ATOM   3040 C  CD  . LYS A  1 395 ? 37.35404 7.43329   -14.14545 1.000 18.69770 ? 426  LYS A CD  1 
ATOM   3041 C  CE  . LYS A  1 395 ? 36.08063 6.99602   -14.86720 1.000 18.49497 ? 426  LYS A CE  1 
ATOM   3042 N  NZ  . LYS A  1 395 ? 34.97076 7.08799   -13.88491 1.000 17.13205 ? 426  LYS A NZ  1 
ATOM   3043 N  N   . ILE A  1 396 ? 39.73003 9.11757   -17.64562 1.000 17.51148 ? 427  ILE A N   1 
ATOM   3044 C  CA  . ILE A  1 396 ? 38.95159 10.03354  -18.46033 1.000 16.66235 ? 427  ILE A CA  1 
ATOM   3045 C  C   . ILE A  1 396 ? 37.48708 9.64703   -18.32745 1.000 16.68880 ? 427  ILE A C   1 
ATOM   3046 O  O   . ILE A  1 396 ? 37.14703 8.46167   -18.22482 1.000 16.56244 ? 427  ILE A O   1 
ATOM   3047 C  CB  . ILE A  1 396 ? 39.40380 10.05782  -19.93004 1.000 19.24679 ? 427  ILE A CB  1 
ATOM   3048 C  CG1 . ILE A  1 396 ? 39.32994 8.65862   -20.54570 1.000 20.79714 ? 427  ILE A CG1 1 
ATOM   3049 C  CG2 . ILE A  1 396 ? 40.81959 10.61704  -20.01136 1.000 18.49388 ? 427  ILE A CG2 1 
ATOM   3050 C  CD1 . ILE A  1 396 ? 39.51919 8.66363   -22.07776 1.000 20.13218 ? 427  ILE A CD1 1 
ATOM   3051 N  N   . THR A  1 397 ? 36.63216 10.65948  -18.26860 1.000 16.63478 ? 428  THR A N   1 
ATOM   3052 C  CA  . THR A  1 397 ? 35.20370 10.46868  -18.09413 1.000 14.83485 ? 428  THR A CA  1 
ATOM   3053 C  C   . THR A  1 397 ? 34.46594 11.39147  -19.04700 1.000 16.98290 ? 428  THR A C   1 
ATOM   3054 O  O   . THR A  1 397 ? 34.79028 12.58065  -19.14359 1.000 17.83766 ? 428  THR A O   1 
ATOM   3055 C  CB  . THR A  1 397 ? 34.77600 10.78335  -16.65347 1.000 17.27825 ? 428  THR A CB  1 
ATOM   3056 O  OG1 . THR A  1 397 ? 35.62763 10.08419  -15.73621 1.000 18.55400 ? 428  THR A OG1 1 
ATOM   3057 C  CG2 . THR A  1 397 ? 33.31366 10.37182  -16.44516 1.000 15.88457 ? 428  THR A CG2 1 
ATOM   3058 N  N   . ARG A  1 398 ? 33.46928 10.85343  -19.74331 1.000 15.86560 ? 429  ARG A N   1 
ATOM   3059 C  CA  . ARG A  1 398 ? 32.47131 11.68530  -20.39343 1.000 16.03858 ? 429  ARG A CA  1 
ATOM   3060 C  C   . ARG A  1 398 ? 31.09761 11.26478  -19.89475 1.000 15.01393 ? 429  ARG A C   1 
ATOM   3061 O  O   . ARG A  1 398 ? 30.72047 10.09688  -20.02512 1.000 16.49533 ? 429  ARG A O   1 
ATOM   3062 C  CB  . ARG A  1 398 ? 32.53121 11.58719  -21.92159 1.000 16.88945 ? 429  ARG A CB  1 
ATOM   3063 C  CG  . ARG A  1 398 ? 31.77835 12.75724  -22.55373 1.000 18.12292 ? 429  ARG A CG  1 
ATOM   3064 C  CD  . ARG A  1 398 ? 31.92691 12.82514  -24.07092 1.000 16.70650 ? 429  ARG A CD  1 
ATOM   3065 N  NE  . ARG A  1 398 ? 31.20791 13.97277  -24.61150 1.000 16.47691 ? 429  ARG A NE  1 
ATOM   3066 C  CZ  . ARG A  1 398 ? 31.06881 14.20633  -25.91127 1.000 18.09797 ? 429  ARG A CZ  1 
ATOM   3067 N  NH1 . ARG A  1 398 ? 31.59306 13.38751  -26.81730 1.000 19.07481 ? 429  ARG A NH1 1 
ATOM   3068 N  NH2 . ARG A  1 398 ? 30.37616 15.27326  -26.31110 1.000 18.81721 ? 429  ARG A NH2 1 
ATOM   3069 N  N   . MET A  1 399 ? 30.36848 12.21932  -19.31618 1.000 16.78163 ? 430  MET A N   1 
ATOM   3070 C  CA  . MET A  1 399 ? 29.01664 12.00383  -18.81315 1.000 14.89833 ? 430  MET A CA  1 
ATOM   3071 C  C   . MET A  1 399 ? 28.09549 13.07712  -19.37249 1.000 17.07224 ? 430  MET A C   1 
ATOM   3072 O  O   . MET A  1 399 ? 28.45071 14.25946  -19.39696 1.000 17.14154 ? 430  MET A O   1 
ATOM   3073 C  CB  . MET A  1 399 ? 28.97931 12.04191  -17.27065 1.000 14.75365 ? 430  MET A CB  1 
ATOM   3074 C  CG  . MET A  1 399 ? 29.34009 10.72126  -16.61326 1.000 15.51518 ? 430  MET A CG  1 
ATOM   3075 S  SD  . MET A  1 399 ? 28.08568 9.46067   -16.91777 1.000 16.50050 ? 430  MET A SD  1 
ATOM   3076 C  CE  . MET A  1 399 ? 26.63935 10.20535  -16.16205 1.000 16.89876 ? 430  MET A CE  1 
ATOM   3077 N  N   . GLY A  1 400 ? 26.90782 12.66020  -19.80367 1.000 15.46156 ? 431  GLY A N   1 
ATOM   3078 C  CA  . GLY A  1 400 ? 25.89435 13.57645  -20.28411 1.000 15.88685 ? 431  GLY A CA  1 
ATOM   3079 C  C   . GLY A  1 400 ? 26.23108 14.24113  -21.58807 1.000 17.04245 ? 431  GLY A C   1 
ATOM   3080 O  O   . GLY A  1 400 ? 25.57665 15.22106  -21.95205 1.000 16.50298 ? 431  GLY A O   1 
ATOM   3081 N  N   . ASN A  1 401 ? 27.22381 13.71172  -22.29736 1.000 16.69883 ? 432  ASN A N   1 
ATOM   3082 C  CA  . ASN A  1 401 ? 27.78953 14.28282  -23.51644 1.000 16.10318 ? 432  ASN A CA  1 
ATOM   3083 C  C   . ASN A  1 401 ? 28.46810 15.63438  -23.27164 1.000 17.92560 ? 432  ASN A C   1 
ATOM   3084 O  O   . ASN A  1 401 ? 28.70302 16.39720  -24.21032 1.000 17.11753 ? 432  ASN A O   1 
ATOM   3085 C  CB  . ASN A  1 401 ? 26.73760 14.39613  -24.62656 1.000 16.97570 ? 432  ASN A CB  1 
ATOM   3086 C  CG  . ASN A  1 401 ? 27.28444 13.95062  -25.97739 1.000 18.97731 ? 432  ASN A CG  1 
ATOM   3087 O  OD1 . ASN A  1 401 ? 28.12947 13.06052  -26.04636 1.000 19.07535 ? 432  ASN A OD1 1 
ATOM   3088 N  ND2 . ASN A  1 401 ? 26.81027 14.57514  -27.04944 1.000 19.88471 ? 432  ASN A ND2 1 
ATOM   3089 N  N   . GLU A  1 402 ? 28.82837 15.93105  -22.02479 1.000 16.83430 ? 433  GLU A N   1 
ATOM   3090 C  CA  . GLU A  1 402 ? 29.57546 17.12997  -21.68673 1.000 19.65806 ? 433  GLU A CA  1 
ATOM   3091 C  C   . GLU A  1 402 ? 31.02562 17.03186  -22.16123 1.000 16.45089 ? 433  GLU A C   1 
ATOM   3092 O  O   . GLU A  1 402 ? 31.47218 15.98152  -22.63399 1.000 16.57043 ? 433  GLU A O   1 
ATOM   3093 C  CB  . GLU A  1 402 ? 29.51802 17.33536  -20.17486 1.000 16.81551 ? 433  GLU A CB  1 
ATOM   3094 C  CG  . GLU A  1 402 ? 28.16599 17.85473  -19.72035 1.000 18.53353 ? 433  GLU A CG  1 
ATOM   3095 C  CD  . GLU A  1 402 ? 27.92054 19.26792  -20.20009 1.000 19.46484 ? 433  GLU A CD  1 
ATOM   3096 O  OE1 . GLU A  1 402 ? 28.68519 20.16495  -19.79322 1.000 22.78958 ? 433  GLU A OE1 1 
ATOM   3097 O  OE2 . GLU A  1 402 ? 26.97929 19.48498  -20.98832 1.000 20.20603 ? 433  GLU A OE2 1 
ATOM   3098 N  N   . PRO A  1 403 ? 31.79866 18.10893  -22.04082 1.000 17.34788 ? 434  PRO A N   1 
ATOM   3099 C  CA  . PRO A  1 403 ? 33.22222 18.01351  -22.38872 1.000 17.20805 ? 434  PRO A CA  1 
ATOM   3100 C  C   . PRO A  1 403 ? 33.93095 16.92451  -21.60314 1.000 17.68259 ? 434  PRO A C   1 
ATOM   3101 O  O   . PRO A  1 403 ? 33.58447 16.61586  -20.45654 1.000 17.71851 ? 434  PRO A O   1 
ATOM   3102 C  CB  . PRO A  1 403 ? 33.77219 19.39928  -22.03469 1.000 18.21932 ? 434  PRO A CB  1 
ATOM   3103 C  CG  . PRO A  1 403 ? 32.58870 20.31745  -22.26037 1.000 18.74138 ? 434  PRO A CG  1 
ATOM   3104 C  CD  . PRO A  1 403 ? 31.39480 19.50749  -21.78132 1.000 18.70953 ? 434  PRO A CD  1 
ATOM   3105 N  N   . TRP A  1 404 ? 34.95239 16.35895  -22.24028 1.000 17.70313 ? 435  TRP A N   1 
ATOM   3106 C  CA  . TRP A  1 404 ? 35.75075 15.30853  -21.62688 1.000 17.01346 ? 435  TRP A CA  1 
ATOM   3107 C  C   . TRP A  1 404 ? 36.43930 15.79506  -20.36200 1.000 18.91925 ? 435  TRP A C   1 
ATOM   3108 O  O   . TRP A  1 404 ? 36.92380 16.92820  -20.28747 1.000 17.96706 ? 435  TRP A O   1 
ATOM   3109 C  CB  . TRP A  1 404 ? 36.80522 14.81595  -22.61456 1.000 19.34197 ? 435  TRP A CB  1 
ATOM   3110 C  CG  . TRP A  1 404 ? 36.26746 13.81308  -23.56061 1.000 17.29852 ? 435  TRP A CG  1 
ATOM   3111 C  CD1 . TRP A  1 404 ? 35.81896 14.02804  -24.84169 1.000 18.72026 ? 435  TRP A CD1 1 
ATOM   3112 C  CD2 . TRP A  1 404 ? 36.09888 12.41741  -23.29848 1.000 18.46252 ? 435  TRP A CD2 1 
ATOM   3113 N  NE1 . TRP A  1 404 ? 35.39220 12.83561  -25.38988 1.000 18.99293 ? 435  TRP A NE1 1 
ATOM   3114 C  CE2 . TRP A  1 404 ? 35.54860 11.83599  -24.46025 1.000 17.76540 ? 435  TRP A CE2 1 
ATOM   3115 C  CE3 . TRP A  1 404 ? 36.37474 11.59895  -22.19465 1.000 16.77150 ? 435  TRP A CE3 1 
ATOM   3116 C  CZ2 . TRP A  1 404 ? 35.27741 10.46918  -24.55124 1.000 19.53847 ? 435  TRP A CZ2 1 
ATOM   3117 C  CZ3 . TRP A  1 404 ? 36.10372 10.25214  -22.28316 1.000 18.62294 ? 435  TRP A CZ3 1 
ATOM   3118 C  CH2 . TRP A  1 404 ? 35.56052 9.69483   -23.45668 1.000 17.28050 ? 435  TRP A CH2 1 
ATOM   3119 N  N   . ARG A  1 405 ? 36.50372 14.91037  -19.36981 1.000 18.43255 ? 436  ARG A N   1 
ATOM   3120 C  CA  . ARG A  1 405 ? 37.19013 15.18492  -18.12076 1.000 16.64968 ? 436  ARG A CA  1 
ATOM   3121 C  C   . ARG A  1 405 ? 38.37953 14.24789  -17.97144 1.000 17.72766 ? 436  ARG A C   1 
ATOM   3122 O  O   . ARG A  1 405 ? 38.31932 13.07154  -18.35196 1.000 18.23145 ? 436  ARG A O   1 
ATOM   3123 C  CB  . ARG A  1 405 ? 36.24108 15.02411  -16.92953 1.000 18.93951 ? 436  ARG A CB  1 
ATOM   3124 C  CG  . ARG A  1 405 ? 34.97756 15.85505  -17.05191 1.000 20.26244 ? 436  ARG A CG  1 
ATOM   3125 C  CD  . ARG A  1 405 ? 33.96379 15.44027  -16.00455 1.000 20.68934 ? 436  ARG A CD  1 
ATOM   3126 N  NE  . ARG A  1 405 ? 34.38537 15.79615  -14.65394 1.000 18.84530 ? 436  ARG A NE  1 
ATOM   3127 C  CZ  . ARG A  1 405 ? 34.20175 16.98529  -14.09833 1.000 22.93772 ? 436  ARG A CZ  1 
ATOM   3128 N  NH1 . ARG A  1 405 ? 33.70545 18.00124  -14.78712 1.000 26.61589 ? 436  ARG A NH1 1 
ATOM   3129 N  NH2 . ARG A  1 405 ? 34.51463 17.15912  -12.81594 1.000 20.98540 ? 436  ARG A NH2 1 
ATOM   3130 N  N   . LEU A  1 406 ? 39.46128 14.77342  -17.41113 1.000 16.72102 ? 437  LEU A N   1 
ATOM   3131 C  CA  . LEU A  1 406 ? 40.60662 13.97370  -17.01495 1.000 17.72580 ? 437  LEU A CA  1 
ATOM   3132 C  C   . LEU A  1 406 ? 40.77498 14.13530  -15.51451 1.000 16.48177 ? 437  LEU A C   1 
ATOM   3133 O  O   . LEU A  1 406 ? 40.82293 15.26443  -15.01285 1.000 18.80541 ? 437  LEU A O   1 
ATOM   3134 C  CB  . LEU A  1 406 ? 41.87542 14.42431  -17.74093 1.000 19.81427 ? 437  LEU A CB  1 
ATOM   3135 C  CG  . LEU A  1 406 ? 43.15846 13.76427  -17.24482 1.000 18.54428 ? 437  LEU A CG  1 
ATOM   3136 C  CD1 . LEU A  1 406 ? 43.21709 12.30306  -17.71611 1.000 18.70108 ? 437  LEU A CD1 1 
ATOM   3137 C  CD2 . LEU A  1 406 ? 44.37937 14.55885  -17.73615 1.000 21.80662 ? 437  LEU A CD2 1 
ATOM   3138 N  N   . HIS A  1 407 ? 40.83825 13.01820  -14.79653 1.000 16.53735 ? 438  HIS A N   1 
ATOM   3139 C  CA  . HIS A  1 407 ? 40.97401 13.06378  -13.34947 1.000 16.81265 ? 438  HIS A CA  1 
ATOM   3140 C  C   . HIS A  1 407 ? 42.15831 12.22601  -12.91021 1.000 16.69703 ? 438  HIS A C   1 
ATOM   3141 O  O   . HIS A  1 407 ? 42.40151 11.14122  -13.44691 1.000 19.58685 ? 438  HIS A O   1 
ATOM   3142 C  CB  . HIS A  1 407 ? 39.69883 12.55414  -12.65390 1.000 18.22524 ? 438  HIS A CB  1 
ATOM   3143 C  CG  . HIS A  1 407 ? 38.50353 13.41136  -12.90569 1.000 17.76896 ? 438  HIS A CG  1 
ATOM   3144 N  ND1 . HIS A  1 407 ? 38.34725 14.64979  -12.32188 1.000 18.93418 ? 438  HIS A ND1 1 
ATOM   3145 C  CD2 . HIS A  1 407 ? 37.40911 13.21501  -13.67933 1.000 19.01040 ? 438  HIS A CD2 1 
ATOM   3146 C  CE1 . HIS A  1 407 ? 37.21610 15.19172  -12.74316 1.000 18.70163 ? 438  HIS A CE1 1 
ATOM   3147 N  NE2 . HIS A  1 407 ? 36.61930 14.33203  -13.55532 1.000 16.60946 ? 438  HIS A NE2 1 
ATOM   3148 N  N   . ASN A  1 408 ? 42.88810 12.72016  -11.91672 1.000 17.15869 ? 439  ASN A N   1 
ATOM   3149 C  CA  . ASN A  1 408 ? 43.77174 11.82603  -11.18638 1.000 16.66386 ? 439  ASN A CA  1 
ATOM   3150 C  C   . ASN A  1 408 ? 42.87217 11.13503  -10.17724 1.000 18.66044 ? 439  ASN A C   1 
ATOM   3151 O  O   . ASN A  1 408 ? 42.51674 11.71778  -9.15176  1.000 17.65624 ? 439  ASN A O   1 
ATOM   3152 C  CB  . ASN A  1 408 ? 44.92079 12.57912  -10.52156 1.000 18.57236 ? 439  ASN A CB  1 
ATOM   3153 C  CG  . ASN A  1 408 ? 45.89822 11.63550  -9.82614  1.000 20.73949 ? 439  ASN A CG  1 
ATOM   3154 O  OD1 . ASN A  1 408 ? 45.49648 10.75239  -9.06937  1.000 19.73097 ? 439  ASN A OD1 1 
ATOM   3155 N  ND2 . ASN A  1 408 ? 47.18241 11.79558  -10.11416 1.000 22.39581 ? 439  ASN A ND2 1 
ATOM   3156 N  N   . ILE A  1 409 ? 42.47248 9.89679   -10.47783 1.000 16.77420 ? 440  ILE A N   1 
ATOM   3157 C  CA  . ILE A  1 409 ? 41.42710 9.27785   -9.66894  1.000 17.41340 ? 440  ILE A CA  1 
ATOM   3158 C  C   . ILE A  1 409 ? 41.94935 8.84808   -8.30706  1.000 18.58900 ? 440  ILE A C   1 
ATOM   3159 O  O   . ILE A  1 409 ? 41.16098 8.68695   -7.36672  1.000 19.75842 ? 440  ILE A O   1 
ATOM   3160 C  CB  . ILE A  1 409 ? 40.78643 8.10162   -10.43175 1.000 18.07443 ? 440  ILE A CB  1 
ATOM   3161 C  CG1 . ILE A  1 409 ? 39.40227 7.79869   -9.84428  1.000 18.60371 ? 440  ILE A CG1 1 
ATOM   3162 C  CG2 . ILE A  1 409 ? 41.68455 6.86723   -10.41557 1.000 19.38492 ? 440  ILE A CG2 1 
ATOM   3163 C  CD1 . ILE A  1 409 ? 38.38731 8.85728   -10.19130 1.000 17.43455 ? 440  ILE A CD1 1 
ATOM   3164 N  N   . THR A  1 410 ? 43.26539 8.69973   -8.15744  1.000 18.25681 ? 441  THR A N   1 
ATOM   3165 C  CA  . THR A  1 410 ? 43.82568 8.38683   -6.84790  1.000 16.21474 ? 441  THR A CA  1 
ATOM   3166 C  C   . THR A  1 410 ? 43.78269 9.60392   -5.93155  1.000 16.38682 ? 441  THR A C   1 
ATOM   3167 O  O   . THR A  1 410 ? 43.48687 9.48071   -4.73686  1.000 20.88186 ? 441  THR A O   1 
ATOM   3168 C  CB  . THR A  1 410 ? 45.25636 7.88635   -7.01515  1.000 18.73843 ? 441  THR A CB  1 
ATOM   3169 O  OG1 . THR A  1 410 ? 45.23060 6.66478   -7.76134  1.000 19.78509 ? 441  THR A OG1 1 
ATOM   3170 C  CG2 . THR A  1 410 ? 45.92891 7.64280   -5.66574  1.000 20.62779 ? 441  THR A CG2 1 
ATOM   3171 N  N   . GLN A  1 411 ? 44.05053 10.78466  -6.47604  1.000 17.12597 ? 442  GLN A N   1 
ATOM   3172 C  CA  . GLN A  1 411 ? 44.06429 12.01485  -5.69458  1.000 15.69697 ? 442  GLN A CA  1 
ATOM   3173 C  C   . GLN A  1 411 ? 42.72389 12.74460  -5.69824  1.000 17.92863 ? 442  GLN A C   1 
ATOM   3174 O  O   . GLN A  1 411 ? 42.53748 13.67471  -4.90079  1.000 20.47469 ? 442  GLN A O   1 
ATOM   3175 C  CB  . GLN A  1 411 ? 45.17688 12.93269  -6.22013  1.000 18.30877 ? 442  GLN A CB  1 
ATOM   3176 C  CG  . GLN A  1 411 ? 46.51778 12.22818  -6.12276  1.000 20.46549 ? 442  GLN A CG  1 
ATOM   3177 C  CD  . GLN A  1 411 ? 47.67969 13.06264  -6.57951  1.000 28.41785 ? 442  GLN A CD  1 
ATOM   3178 O  OE1 . GLN A  1 411 ? 47.50387 14.13458  -7.14221  1.000 31.21437 ? 442  GLN A OE1 1 
ATOM   3179 N  NE2 . GLN A  1 411 ? 48.88567 12.56644  -6.33535  1.000 32.70398 ? 442  GLN A NE2 1 
ATOM   3180 N  N   . ASP A  1 412 ? 41.77795 12.32129  -6.54018  1.000 18.78070 ? 443  ASP A N   1 
ATOM   3181 C  CA  . ASP A  1 412 ? 40.50594 13.00908  -6.75897  1.000 17.78121 ? 443  ASP A CA  1 
ATOM   3182 C  C   . ASP A  1 412 ? 39.44746 11.93649  -7.03037  1.000 17.62515 ? 443  ASP A C   1 
ATOM   3183 O  O   . ASP A  1 412 ? 38.87301 11.83292  -8.12532  1.000 17.36890 ? 443  ASP A O   1 
ATOM   3184 C  CB  . ASP A  1 412 ? 40.64294 14.00572  -7.91134  1.000 18.96474 ? 443  ASP A CB  1 
ATOM   3185 C  CG  . ASP A  1 412 ? 39.35517 14.72541  -8.26019  1.000 18.62581 ? 443  ASP A CG  1 
ATOM   3186 O  OD1 . ASP A  1 412 ? 38.44187 14.85509  -7.41328  1.000 18.66460 ? 443  ASP A OD1 1 
ATOM   3187 O  OD2 . ASP A  1 412 ? 39.27607 15.18753  -9.41219  1.000 19.99652 ? 443  ASP A OD2 1 
ATOM   3188 N  N   . ILE A  1 413 ? 39.19241 11.10983  -6.01294  1.000 16.52765 ? 444  ILE A N   1 
ATOM   3189 C  CA  . ILE A  1 413 ? 38.36234 9.92340   -6.22352  1.000 16.79641 ? 444  ILE A CA  1 
ATOM   3190 C  C   . ILE A  1 413 ? 36.93166 10.31000  -6.56569  1.000 17.37865 ? 444  ILE A C   1 
ATOM   3191 O  O   . ILE A  1 413 ? 36.22187 9.54327   -7.23904  1.000 16.67817 ? 444  ILE A O   1 
ATOM   3192 C  CB  . ILE A  1 413 ? 38.43416 9.00800   -4.98320  1.000 17.97085 ? 444  ILE A CB  1 
ATOM   3193 C  CG1 . ILE A  1 413 ? 37.80815 7.64307   -5.26998  1.000 18.56933 ? 444  ILE A CG1 1 
ATOM   3194 C  CG2 . ILE A  1 413 ? 37.75764 9.65526   -3.78821  1.000 18.42902 ? 444  ILE A CG2 1 
ATOM   3195 C  CD1 . ILE A  1 413 ? 38.03995 6.63179   -4.16407  1.000 19.11133 ? 444  ILE A CD1 1 
ATOM   3196 N  N   . GLY A  1 414 ? 36.48449 11.49834  -6.13074  1.000 17.51586 ? 445  GLY A N   1 
ATOM   3197 C  CA  . GLY A  1 414 ? 35.16405 12.02035  -6.43675  1.000 16.64729 ? 445  GLY A CA  1 
ATOM   3198 C  C   . GLY A  1 414 ? 35.01190 12.70515  -7.78000  1.000 17.48169 ? 445  GLY A C   1 
ATOM   3199 O  O   . GLY A  1 414 ? 33.94066 13.25424  -8.06218  1.000 17.77401 ? 445  GLY A O   1 
ATOM   3200 N  N   . GLU A  1 415 ? 36.05477 12.70581  -8.60983  1.000 14.83100 ? 446  GLU A N   1 
ATOM   3201 C  CA  . GLU A  1 415 ? 35.98847 13.26260  -9.96600  1.000 15.23012 ? 446  GLU A CA  1 
ATOM   3202 C  C   . GLU A  1 415 ? 35.49256 14.71078  -9.95858  1.000 16.71896 ? 446  GLU A C   1 
ATOM   3203 O  O   . GLU A  1 415 ? 34.62109 15.11082  -10.73614 1.000 17.00945 ? 446  GLU A O   1 
ATOM   3204 C  CB  . GLU A  1 415 ? 35.12154 12.37571  -10.86538 1.000 16.21341 ? 446  GLU A CB  1 
ATOM   3205 C  CG  . GLU A  1 415 ? 35.76193 10.99092  -11.11154 1.000 14.97822 ? 446  GLU A CG  1 
ATOM   3206 C  CD  . GLU A  1 415 ? 34.82286 10.01755  -11.79747 1.000 18.59239 ? 446  GLU A CD  1 
ATOM   3207 O  OE1 . GLU A  1 415 ? 33.89531 9.51504   -11.12216 1.000 15.49843 ? 446  GLU A OE1 1 
ATOM   3208 O  OE2 . GLU A  1 415 ? 34.99449 9.76435   -13.02463 1.000 18.17485 ? 446  GLU A OE2 1 
ATOM   3209 N  N   . LYS A  1 416 ? 36.07521 15.51288  -9.06635  1.000 17.49356 ? 447  LYS A N   1 
ATOM   3210 C  CA  . LYS A  1 416 ? 35.66261 16.90301  -8.90290  1.000 16.52613 ? 447  LYS A CA  1 
ATOM   3211 C  C   . LYS A  1 416 ? 36.49408 17.88579  -9.71574  1.000 19.01570 ? 447  LYS A C   1 
ATOM   3212 O  O   . LYS A  1 416 ? 36.00544 18.96895  -10.05561 1.000 20.77616 ? 447  LYS A O   1 
ATOM   3213 C  CB  . LYS A  1 416 ? 35.75384 17.29763  -7.42916  1.000 17.40994 ? 447  LYS A CB  1 
ATOM   3214 C  CG  . LYS A  1 416 ? 34.79115 16.54014  -6.55026  1.000 19.89885 ? 447  LYS A CG  1 
ATOM   3215 C  CD  . LYS A  1 416 ? 34.93059 16.98159  -5.09410  1.000 23.44309 ? 447  LYS A CD  1 
ATOM   3216 C  CE  . LYS A  1 416 ? 33.80969 16.41145  -4.24244  1.000 27.38067 ? 447  LYS A CE  1 
ATOM   3217 N  NZ  . LYS A  1 416 ? 33.96069 16.81615  -2.81523  1.000 32.95921 ? 447  LYS A NZ  1 
ATOM   3218 N  N   . LYS A  1 417 ? 37.74385 17.55046  -10.01753 1.000 18.67222 ? 448  LYS A N   1 
ATOM   3219 C  CA  . LYS A  1 417 ? 38.70560 18.51540  -10.54574 1.000 18.09078 ? 448  LYS A CA  1 
ATOM   3220 C  C   . LYS A  1 417 ? 39.15143 18.07083  -11.93492 1.000 17.33259 ? 448  LYS A C   1 
ATOM   3221 O  O   . LYS A  1 417 ? 39.99905 17.18157  -12.06962 1.000 18.84477 ? 448  LYS A O   1 
ATOM   3222 C  CB  . LYS A  1 417 ? 39.88687 18.65381  -9.59714  1.000 22.13899 ? 448  LYS A CB  1 
ATOM   3223 C  CG  . LYS A  1 417 ? 39.46945 18.97959  -8.16533  1.000 25.97207 ? 448  LYS A CG  1 
ATOM   3224 C  CD  . LYS A  1 417 ? 38.61693 20.23663  -8.14849  1.000 30.61653 ? 448  LYS A CD  1 
ATOM   3225 C  CE  . LYS A  1 417 ? 38.17996 20.59877  -6.74631  1.000 32.21847 ? 448  LYS A CE  1 
ATOM   3226 N  NZ  . LYS A  1 417 ? 38.52695 19.52899  -5.77149  1.000 42.07574 ? 448  LYS A NZ  1 
ATOM   3227 N  N   . ASN A  1 418 ? 38.59214 18.70539  -12.95956 1.000 19.13271 ? 449  ASN A N   1 
ATOM   3228 C  CA  . ASN A  1 418 ? 38.91589 18.35503  -14.33440 1.000 18.96653 ? 449  ASN A CA  1 
ATOM   3229 C  C   . ASN A  1 418 ? 40.28554 18.91867  -14.70394 1.000 22.41153 ? 449  ASN A C   1 
ATOM   3230 O  O   . ASN A  1 418 ? 40.48150 20.14058  -14.71166 1.000 22.55149 ? 449  ASN A O   1 
ATOM   3231 C  CB  . ASN A  1 418 ? 37.83147 18.88386  -15.26917 1.000 19.09292 ? 449  ASN A CB  1 
ATOM   3232 C  CG  . ASN A  1 418 ? 38.02261 18.42308  -16.69217 1.000 19.57917 ? 449  ASN A CG  1 
ATOM   3233 O  OD1 . ASN A  1 418 ? 38.95722 17.69005  -16.99538 1.000 19.08197 ? 449  ASN A OD1 1 
ATOM   3234 N  ND2 . ASN A  1 418 ? 37.13435 18.85541  -17.57305 1.000 21.20734 ? 449  ASN A ND2 1 
ATOM   3235 N  N   . LEU A  1 419 ? 41.22410 18.02610  -15.01038 1.000 18.45018 ? 450  LEU A N   1 
ATOM   3236 C  CA  . LEU A  1 419 ? 42.58828 18.38580  -15.37148 1.000 20.30873 ? 450  LEU A CA  1 
ATOM   3237 C  C   . LEU A  1 419 ? 42.82892 18.31427  -16.87087 1.000 21.57082 ? 450  LEU A C   1 
ATOM   3238 O  O   . LEU A  1 419 ? 43.98831 18.33180  -17.30283 1.000 23.04851 ? 450  LEU A O   1 
ATOM   3239 C  CB  . LEU A  1 419 ? 43.58303 17.48186  -14.63989 1.000 22.22207 ? 450  LEU A CB  1 
ATOM   3240 C  CG  . LEU A  1 419 ? 43.49954 17.52499  -13.11250 1.000 20.68873 ? 450  LEU A CG  1 
ATOM   3241 C  CD1 . LEU A  1 419 ? 44.41996 16.50702  -12.48286 1.000 23.38468 ? 450  LEU A CD1 1 
ATOM   3242 C  CD2 . LEU A  1 419 ? 43.83831 18.93118  -12.60834 1.000 29.05930 ? 450  LEU A CD2 1 
ATOM   3243 N  N   . ALA A  1 420 ? 41.76251 18.22938  -17.66873 1.000 21.66387 ? 451  ALA A N   1 
ATOM   3244 C  CA  . ALA A  1 420 ? 41.91309 18.11366  -19.11715 1.000 21.02719 ? 451  ALA A CA  1 
ATOM   3245 C  C   . ALA A  1 420 ? 42.70304 19.27939  -19.69692 1.000 29.09094 ? 451  ALA A C   1 
ATOM   3246 O  O   . ALA A  1 420 ? 43.45459 19.10295  -20.66355 1.000 28.18970 ? 451  ALA A O   1 
ATOM   3247 C  CB  . ALA A  1 420 ? 40.54150 18.03407  -19.78377 1.000 24.78644 ? 451  ALA A CB  1 
ATOM   3248 N  N   . GLY A  1 421 ? 42.52364 20.48445  -19.14355 1.000 25.15888 ? 452  GLY A N   1 
ATOM   3249 C  CA  . GLY A  1 421 ? 43.25285 21.63625  -19.65024 1.000 27.65423 ? 452  GLY A CA  1 
ATOM   3250 C  C   . GLY A  1 421 ? 44.71158 21.63627  -19.24840 1.000 30.34390 ? 452  GLY A C   1 
ATOM   3251 O  O   . GLY A  1 421 ? 45.55439 22.19711  -19.95491 1.000 33.29976 ? 452  GLY A O   1 
ATOM   3252 N  N   . ARG A  1 422 ? 45.03405 21.00659  -18.12021 1.000 25.95590 ? 453  ARG A N   1 
ATOM   3253 C  CA  . ARG A  1 422 ? 46.40992 20.98975  -17.64022 1.000 27.62816 ? 453  ARG A CA  1 
ATOM   3254 C  C   . ARG A  1 422 ? 47.24642 19.92235  -18.33482 1.000 30.16163 ? 453  ARG A C   1 
ATOM   3255 O  O   . ARG A  1 422 ? 48.43524 20.13791  -18.59401 1.000 29.71542 ? 453  ARG A O   1 
ATOM   3256 C  CB  . ARG A  1 422 ? 46.43305 20.77373  -16.12826 1.000 30.21430 ? 453  ARG A CB  1 
ATOM   3257 C  CG  . ARG A  1 422 ? 47.83123 20.74864  -15.52480 1.000 32.17818 ? 453  ARG A CG  1 
ATOM   3258 C  CD  . ARG A  1 422 ? 47.74829 20.79225  -14.01615 1.000 34.09471 ? 453  ARG A CD  1 
ATOM   3259 N  NE  . ARG A  1 422 ? 46.69649 21.70557  -13.58865 1.000 45.97476 ? 453  ARG A NE  1 
ATOM   3260 C  CZ  . ARG A  1 422 ? 46.27054 21.82505  -12.33976 1.000 47.78200 ? 453  ARG A CZ  1 
ATOM   3261 N  NH1 . ARG A  1 422 ? 46.79497 21.10752  -11.36075 1.000 47.15513 ? 453  ARG A NH1 1 
ATOM   3262 N  NH2 . ARG A  1 422 ? 45.29165 22.68331  -12.06799 1.000 49.49234 ? 453  ARG A NH2 1 
ATOM   3263 N  N   . TYR A  1 423 ? 46.65896 18.77120  -18.65373 1.000 26.06776 ? 454  TYR A N   1 
ATOM   3264 C  CA  . TYR A  1 423 ? 47.39429 17.66882  -19.27760 1.000 25.37594 ? 454  TYR A CA  1 
ATOM   3265 C  C   . TYR A  1 423 ? 46.68888 17.21400  -20.54890 1.000 24.08220 ? 454  TYR A C   1 
ATOM   3266 O  O   . TYR A  1 423 ? 46.22805 16.07024  -20.65187 1.000 24.70507 ? 454  TYR A O   1 
ATOM   3267 C  CB  . TYR A  1 423 ? 47.56272 16.51429  -18.29415 1.000 23.62166 ? 454  TYR A CB  1 
ATOM   3268 C  CG  . TYR A  1 423 ? 48.20632 16.92751  -16.98786 1.000 30.78966 ? 454  TYR A CG  1 
ATOM   3269 C  CD1 . TYR A  1 423 ? 49.52347 17.38028  -16.94995 1.000 34.25316 ? 454  TYR A CD1 1 
ATOM   3270 C  CD2 . TYR A  1 423 ? 47.50061 16.86797  -15.79098 1.000 26.71616 ? 454  TYR A CD2 1 
ATOM   3271 C  CE1 . TYR A  1 423 ? 50.11651 17.75866  -15.75435 1.000 32.78352 ? 454  TYR A CE1 1 
ATOM   3272 C  CE2 . TYR A  1 423 ? 48.08415 17.23950  -14.59610 1.000 31.31401 ? 454  TYR A CE2 1 
ATOM   3273 C  CZ  . TYR A  1 423 ? 49.39229 17.68462  -14.58274 1.000 37.26750 ? 454  TYR A CZ  1 
ATOM   3274 O  OH  . TYR A  1 423 ? 49.97388 18.05730  -13.39260 1.000 34.75654 ? 454  TYR A OH  1 
ATOM   3275 N  N   . PRO A  1 424 ? 46.61892 18.08354  -21.55980 1.000 25.92932 ? 455  PRO A N   1 
ATOM   3276 C  CA  . PRO A  1 424 ? 45.90611 17.71460  -22.79233 1.000 26.42039 ? 455  PRO A CA  1 
ATOM   3277 C  C   . PRO A  1 424 ? 46.50167 16.51569  -23.51168 1.000 24.75107 ? 455  PRO A C   1 
ATOM   3278 O  O   . PRO A  1 424 ? 45.75271 15.73955  -24.11908 1.000 24.60638 ? 455  PRO A O   1 
ATOM   3279 C  CB  . PRO A  1 424 ? 46.00083 18.99007  -23.64471 1.000 29.09259 ? 455  PRO A CB  1 
ATOM   3280 C  CG  . PRO A  1 424 ? 47.20972 19.69701  -23.13950 1.000 29.30781 ? 455  PRO A CG  1 
ATOM   3281 C  CD  . PRO A  1 424 ? 47.25169 19.41288  -21.65983 1.000 29.09122 ? 455  PRO A CD  1 
ATOM   3282 N  N   . ASP A  1 425 ? 47.82339 16.33530  -23.47001 1.000 25.98495 ? 456  ASP A N   1 
ATOM   3283 C  CA  . ASP A  1 425 ? 48.42056 15.19739  -24.16107 1.000 26.07766 ? 456  ASP A CA  1 
ATOM   3284 C  C   . ASP A  1 425 ? 47.97273 13.87635  -23.54516 1.000 27.03580 ? 456  ASP A C   1 
ATOM   3285 O  O   . ASP A  1 425 ? 47.66243 12.92268  -24.27106 1.000 23.90752 ? 456  ASP A O   1 
ATOM   3286 C  CB  . ASP A  1 425 ? 49.94452 15.30669  -24.14174 1.000 28.44935 ? 456  ASP A CB  1 
ATOM   3287 C  CG  . ASP A  1 425 ? 50.45466 16.50710  -24.92697 1.000 35.37217 ? 456  ASP A CG  1 
ATOM   3288 O  OD1 . ASP A  1 425 ? 49.66750 17.11933  -25.67621 1.000 37.74596 ? 456  ASP A OD1 1 
ATOM   3289 O  OD2 . ASP A  1 425 ? 51.64694 16.84238  -24.78206 1.000 43.00081 ? 456  ASP A OD2 1 
ATOM   3290 N  N   . ARG A  1 426 ? 47.94340 13.80024  -22.20999 1.000 25.31665 ? 457  ARG A N   1 
ATOM   3291 C  CA  . ARG A  1 426 ? 47.47140 12.59154  -21.54254 1.000 26.78054 ? 457  ARG A CA  1 
ATOM   3292 C  C   . ARG A  1 426 ? 46.00980 12.32472  -21.86931 1.000 21.32467 ? 457  ARG A C   1 
ATOM   3293 O  O   . ARG A  1 426 ? 45.63163 11.18671  -22.16407 1.000 23.00935 ? 457  ARG A O   1 
ATOM   3294 C  CB  . ARG A  1 426 ? 47.66625 12.70810  -20.02541 1.000 25.84185 ? 457  ARG A CB  1 
ATOM   3295 C  CG  . ARG A  1 426 ? 47.18248 11.47872  -19.25818 1.000 27.57757 ? 457  ARG A CG  1 
ATOM   3296 C  CD  . ARG A  1 426 ? 47.47240 11.56231  -17.76508 1.000 27.24648 ? 457  ARG A CD  1 
ATOM   3297 N  NE  . ARG A  1 426 ? 48.87935 11.82230  -17.47040 1.000 34.03131 ? 457  ARG A NE  1 
ATOM   3298 C  CZ  . ARG A  1 426 ? 49.81452 10.88610  -17.37324 1.000 38.27322 ? 457  ARG A CZ  1 
ATOM   3299 N  NH1 . ARG A  1 426 ? 49.53897 9.60597   -17.57590 1.000 34.88744 ? 457  ARG A NH1 1 
ATOM   3300 N  NH2 . ARG A  1 426 ? 51.05954 11.24267  -17.06539 1.000 38.47226 ? 457  ARG A NH2 1 
ATOM   3301 N  N   . LEU A  1 427 ? 45.17302 13.36770  -21.82640 1.000 21.43101 ? 458  LEU A N   1 
ATOM   3302 C  CA  . LEU A  1 427 ? 43.76877 13.20677  -22.18706 1.000 21.00552 ? 458  LEU A CA  1 
ATOM   3303 C  C   . LEU A  1 427 ? 43.62438 12.59929  -23.57579 1.000 22.89318 ? 458  LEU A C   1 
ATOM   3304 O  O   . LEU A  1 427 ? 42.89903 11.61689  -23.76414 1.000 23.52297 ? 458  LEU A O   1 
ATOM   3305 C  CB  . LEU A  1 427 ? 43.04884 14.55374  -22.11813 1.000 22.08169 ? 458  LEU A CB  1 
ATOM   3306 C  CG  . LEU A  1 427 ? 41.64322 14.58097  -22.72826 1.000 26.22851 ? 458  LEU A CG  1 
ATOM   3307 C  CD1 . LEU A  1 427 ? 40.64775 13.81589  -21.86330 1.000 28.98702 ? 458  LEU A CD1 1 
ATOM   3308 C  CD2 . LEU A  1 427 ? 41.17705 16.01720  -22.94799 1.000 29.45393 ? 458  LEU A CD2 1 
ATOM   3309 N  N   . LYS A  1 428 ? 44.35440 13.13830  -24.55456 1.000 21.64647 ? 459  LYS A N   1 
ATOM   3310 C  CA  . LYS A  1 428 ? 44.16153 12.67924  -25.92506 1.000 24.66886 ? 459  LYS A CA  1 
ATOM   3311 C  C   . LYS A  1 428 ? 44.75981 11.30028  -26.16341 1.000 24.04008 ? 459  LYS A C   1 
ATOM   3312 O  O   . LYS A  1 428 ? 44.22304 10.53280  -26.97610 1.000 25.16790 ? 459  LYS A O   1 
ATOM   3313 C  CB  . LYS A  1 428 ? 44.73149 13.70378  -26.89947 1.000 24.97136 ? 459  LYS A CB  1 
ATOM   3314 C  CG  . LYS A  1 428 ? 43.96008 15.02134  -26.82490 1.000 29.51831 ? 459  LYS A CG  1 
ATOM   3315 C  CD  . LYS A  1 428 ? 43.84590 15.70412  -28.17130 1.000 37.82677 ? 459  LYS A CD  1 
ATOM   3316 C  CE  . LYS A  1 428 ? 42.85905 16.86589  -28.10342 1.000 36.59038 ? 459  LYS A CE  1 
ATOM   3317 N  NZ  . LYS A  1 428 ? 43.48560 18.13931  -28.54257 1.000 42.96208 ? 459  LYS A NZ  1 
ATOM   3318 N  N   . GLU A  1 429 ? 45.85860 10.96668  -25.48036 1.000 23.79715 ? 460  GLU A N   1 
ATOM   3319 C  CA  . GLU A  1 429 ? 46.37259 9.60001   -25.54049 1.000 25.04835 ? 460  GLU A CA  1 
ATOM   3320 C  C   . GLU A  1 429 ? 45.34451 8.60930   -25.01738 1.000 24.28071 ? 460  GLU A C   1 
ATOM   3321 O  O   . GLU A  1 429 ? 45.12208 7.55436   -25.61690 1.000 24.35735 ? 460  GLU A O   1 
ATOM   3322 C  CB  . GLU A  1 429 ? 47.66609 9.47087   -24.73500 1.000 28.07857 ? 460  GLU A CB  1 
ATOM   3323 C  CG  . GLU A  1 429 ? 48.86799 10.15153  -25.34836 1.000 34.82768 ? 460  GLU A CG  1 
ATOM   3324 C  CD  . GLU A  1 429 ? 50.01502 10.29033  -24.36125 1.000 43.87631 ? 460  GLU A CD  1 
ATOM   3325 O  OE1 . GLU A  1 429 ? 49.85495 9.86738   -23.19328 1.000 47.59609 ? 460  GLU A OE1 1 
ATOM   3326 O  OE2 . GLU A  1 429 ? 51.07148 10.83244  -24.75065 1.000 53.20870 ? 460  GLU A OE2 1 
ATOM   3327 N  N   . MET A  1 430 ? 44.70646 8.93324   -23.89379 1.000 21.97042 ? 461  MET A N   1 
ATOM   3328 C  CA  . MET A  1 430 ? 43.71799 8.02120   -23.32744 1.000 21.53204 ? 461  MET A CA  1 
ATOM   3329 C  C   . MET A  1 430 ? 42.47166 7.94158   -24.20276 1.000 19.99539 ? 461  MET A C   1 
ATOM   3330 O  O   . MET A  1 430 ? 41.87698 6.86567   -24.34425 1.000 20.77213 ? 461  MET A O   1 
ATOM   3331 C  CB  . MET A  1 430 ? 43.38051 8.46563   -21.90590 1.000 20.04695 ? 461  MET A CB  1 
ATOM   3332 C  CG  . MET A  1 430 ? 44.55732 8.28578   -20.96549 1.000 21.06066 ? 461  MET A CG  1 
ATOM   3333 S  SD  . MET A  1 430 ? 44.23763 8.73264   -19.24382 1.000 22.82088 ? 461  MET A SD  1 
ATOM   3334 C  CE  . MET A  1 430 ? 43.21430 7.37389   -18.66726 1.000 20.34138 ? 461  MET A CE  1 
ATOM   3335 N  N   . ILE A  1 431 ? 42.07245 9.06895   -24.80120 1.000 21.47693 ? 462  ILE A N   1 
ATOM   3336 C  CA  . ILE A  1 431 ? 40.96812 9.07618   -25.75798 1.000 23.22550 ? 462  ILE A CA  1 
ATOM   3337 C  C   . ILE A  1 431 ? 41.27277 8.15171   -26.92650 1.000 23.54096 ? 462  ILE A C   1 
ATOM   3338 O  O   . ILE A  1 431 ? 40.41881 7.37009   -27.36036 1.000 22.23512 ? 462  ILE A O   1 
ATOM   3339 C  CB  . ILE A  1 431 ? 40.70549 10.51157  -26.25053 1.000 23.52979 ? 462  ILE A CB  1 
ATOM   3340 C  CG1 . ILE A  1 431 ? 40.07421 11.35289  -25.15082 1.000 29.71769 ? 462  ILE A CG1 1 
ATOM   3341 C  CG2 . ILE A  1 431 ? 39.83764 10.50014  -27.52124 1.000 24.72485 ? 462  ILE A CG2 1 
ATOM   3342 C  CD1 . ILE A  1 431 ? 38.64084 11.09564  -25.00543 1.000 30.01453 ? 462  ILE A CD1 1 
ATOM   3343 N  N   . ALA A  1 432 ? 42.49447 8.23351   -27.45683 1.000 24.04132 ? 463  ALA A N   1 
ATOM   3344 C  CA  . ALA A  1 432 ? 42.85680 7.43113   -28.62312 1.000 25.71596 ? 463  ALA A CA  1 
ATOM   3345 C  C   . ALA A  1 432 ? 42.74788 5.94095   -28.33585 1.000 23.05026 ? 463  ALA A C   1 
ATOM   3346 O  O   . ALA A  1 432 ? 42.23389 5.17988   -29.16289 1.000 25.82499 ? 463  ALA A O   1 
ATOM   3347 C  CB  . ALA A  1 432 ? 44.27461 7.78087   -29.08172 1.000 26.20095 ? 463  ALA A CB  1 
ATOM   3348 N  N   . LYS A  1 433 ? 43.24052 5.49941   -27.17416 1.000 21.98591 ? 464  LYS A N   1 
ATOM   3349 C  CA  . LYS A  1 433 ? 43.17193 4.08456   -26.84044 1.000 22.18358 ? 464  LYS A CA  1 
ATOM   3350 C  C   . LYS A  1 433 ? 41.73097 3.64152   -26.64312 1.000 22.75827 ? 464  LYS A C   1 
ATOM   3351 O  O   . LYS A  1 433 ? 41.34246 2.56023   -27.09156 1.000 23.88438 ? 464  LYS A O   1 
ATOM   3352 C  CB  . LYS A  1 433 ? 44.00438 3.79620   -25.58952 1.000 25.11310 ? 464  LYS A CB  1 
ATOM   3353 N  N   . THR A  1 434 ? 40.91790 4.47963   -25.99701 1.000 21.08517 ? 465  THR A N   1 
ATOM   3354 C  CA  . THR A  1 434 ? 39.51673 4.13617   -25.78282 1.000 19.02734 ? 465  THR A CA  1 
ATOM   3355 C  C   . THR A  1 434 ? 38.76370 4.07090   -27.10498 1.000 20.65153 ? 465  THR A C   1 
ATOM   3356 O  O   . THR A  1 434 ? 37.94812 3.16538   -27.31713 1.000 20.70964 ? 465  THR A O   1 
ATOM   3357 C  CB  . THR A  1 434 ? 38.88443 5.15285   -24.82926 1.000 18.29497 ? 465  THR A CB  1 
ATOM   3358 O  OG1 . THR A  1 434 ? 39.69729 5.23468   -23.65024 1.000 20.43690 ? 465  THR A OG1 1 
ATOM   3359 C  CG2 . THR A  1 434 ? 37.46472 4.71635   -24.43822 1.000 19.63371 ? 465  THR A CG2 1 
ATOM   3360 N  N   . GLN A  1 435 ? 39.03926 5.00711   -28.01472 1.000 21.64792 ? 466  GLN A N   1 
ATOM   3361 C  CA  . GLN A  1 435 ? 38.39801 4.95920   -29.32189 1.000 22.36405 ? 466  GLN A CA  1 
ATOM   3362 C  C   . GLN A  1 435 ? 38.79178 3.69522   -30.07391 1.000 21.12369 ? 466  GLN A C   1 
ATOM   3363 O  O   . GLN A  1 435 ? 37.95191 3.06158   -30.72582 1.000 23.18238 ? 466  GLN A O   1 
ATOM   3364 C  CB  . GLN A  1 435 ? 38.76100 6.20128   -30.14035 1.000 22.06370 ? 466  GLN A CB  1 
ATOM   3365 C  CG  . GLN A  1 435 ? 38.02813 6.25791   -31.47145 1.000 22.65110 ? 466  GLN A CG  1 
ATOM   3366 C  CD  . GLN A  1 435 ? 38.07734 7.61773   -32.12529 1.000 27.11920 ? 466  GLN A CD  1 
ATOM   3367 O  OE1 . GLN A  1 435 ? 38.97432 8.41991   -31.86423 1.000 30.93293 ? 466  GLN A OE1 1 
ATOM   3368 N  NE2 . GLN A  1 435 ? 37.09911 7.89145   -32.97453 1.000 32.08530 ? 466  GLN A NE2 1 
ATOM   3369 N  N   . GLU A  1 436 ? 40.06811 3.32021   -30.00198 1.000 23.64805 ? 467  GLU A N   1 
ATOM   3370 C  CA  . GLU A  1 436 ? 40.50839 2.09147   -30.65370 1.000 26.27446 ? 467  GLU A CA  1 
ATOM   3371 C  C   . GLU A  1 436 ? 39.74358 0.88916   -30.11651 1.000 26.16527 ? 467  GLU A C   1 
ATOM   3372 O  O   . GLU A  1 436 ? 39.37731 -0.01862  -30.87476 1.000 23.74982 ? 467  GLU A O   1 
ATOM   3373 C  CB  . GLU A  1 436 ? 42.01291 1.91041   -30.45710 1.000 28.58217 ? 467  GLU A CB  1 
ATOM   3374 C  CG  . GLU A  1 436 ? 42.58766 0.68162   -31.14658 1.000 37.53503 ? 467  GLU A CG  1 
ATOM   3375 C  CD  . GLU A  1 436 ? 42.75202 0.85848   -32.64584 1.000 49.75124 ? 467  GLU A CD  1 
ATOM   3376 O  OE1 . GLU A  1 436 ? 42.42937 1.95041   -33.16909 1.000 46.35481 ? 467  GLU A OE1 1 
ATOM   3377 O  OE2 . GLU A  1 436 ? 43.21264 -0.10421  -33.30021 1.000 53.63426 ? 467  GLU A OE2 1 
ATOM   3378 N  N   . TRP A  1 437 ? 39.48430 0.87739   -28.80679 1.000 21.79228 ? 468  TRP A N   1 
ATOM   3379 C  CA  . TRP A  1 437 ? 38.72172 -0.20120  -28.19430 1.000 21.21907 ? 468  TRP A CA  1 
ATOM   3380 C  C   . TRP A  1 437 ? 37.34346 -0.33087  -28.83687 1.000 20.63405 ? 468  TRP A C   1 
ATOM   3381 O  O   . TRP A  1 437 ? 36.90461 -1.43914  -29.17088 1.000 22.18127 ? 468  TRP A O   1 
ATOM   3382 C  CB  . TRP A  1 437 ? 38.63136 0.05819   -26.68165 1.000 21.89656 ? 468  TRP A CB  1 
ATOM   3383 C  CG  . TRP A  1 437 ? 37.73009 -0.84564  -25.87212 1.000 21.00529 ? 468  TRP A CG  1 
ATOM   3384 C  CD1 . TRP A  1 437 ? 37.81601 -2.21159  -25.72703 1.000 23.65919 ? 468  TRP A CD1 1 
ATOM   3385 C  CD2 . TRP A  1 437 ? 36.63567 -0.42580  -25.04417 1.000 19.60047 ? 468  TRP A CD2 1 
ATOM   3386 N  NE1 . TRP A  1 437 ? 36.82409 -2.65804  -24.88129 1.000 21.04352 ? 468  TRP A NE1 1 
ATOM   3387 C  CE2 . TRP A  1 437 ? 36.09397 -1.58312  -24.44430 1.000 20.93955 ? 468  TRP A CE2 1 
ATOM   3388 C  CE3 . TRP A  1 437 ? 36.06279 0.81572   -24.75683 1.000 20.49041 ? 468  TRP A CE3 1 
ATOM   3389 C  CZ2 . TRP A  1 437 ? 34.99911 -1.53182  -23.58266 1.000 20.67427 ? 468  TRP A CZ2 1 
ATOM   3390 C  CZ3 . TRP A  1 437 ? 34.96709 0.86337   -23.89923 1.000 20.77634 ? 468  TRP A CZ3 1 
ATOM   3391 C  CH2 . TRP A  1 437 ? 34.45602 -0.30529  -23.32006 1.000 19.40594 ? 468  TRP A CH2 1 
ATOM   3392 N  N   . THR A  1 438 ? 36.65187 0.79719   -29.04199 1.000 21.07980 ? 469  THR A N   1 
ATOM   3393 C  CA  . THR A  1 438 ? 35.30775 0.73885   -29.61468 1.000 20.85501 ? 469  THR A CA  1 
ATOM   3394 C  C   . THR A  1 438 ? 35.30563 0.24670   -31.05509 1.000 22.60671 ? 469  THR A C   1 
ATOM   3395 O  O   . THR A  1 438 ? 34.25482 -0.17584  -31.54349 1.000 24.04045 ? 469  THR A O   1 
ATOM   3396 C  CB  . THR A  1 438 ? 34.60100 2.09951   -29.55887 1.000 20.39220 ? 469  THR A CB  1 
ATOM   3397 O  OG1 . THR A  1 438 ? 35.22973 3.02551   -30.45729 1.000 24.65111 ? 469  THR A OG1 1 
ATOM   3398 C  CG2 . THR A  1 438 ? 34.61280 2.65867   -28.15449 1.000 19.30771 ? 469  THR A CG2 1 
ATOM   3399 N  N   . LYS A  1 439 ? 36.45087 0.27928   -31.74496 1.000 22.32018 ? 470  LYS A N   1 
ATOM   3400 C  CA  . LYS A  1 439 ? 36.48377 -0.25687  -33.10156 1.000 29.02220 ? 470  LYS A CA  1 
ATOM   3401 C  C   . LYS A  1 439 ? 36.27848 -1.76661  -33.13463 1.000 26.40741 ? 470  LYS A C   1 
ATOM   3402 O  O   . LYS A  1 439 ? 35.99182 -2.31900  -34.20429 1.000 27.71056 ? 470  LYS A O   1 
ATOM   3403 C  CB  . LYS A  1 439 ? 37.80204 0.11282   -33.77947 1.000 25.74086 ? 470  LYS A CB  1 
ATOM   3404 C  CG  . LYS A  1 439 ? 37.93104 1.59325   -34.06815 1.000 32.22914 ? 470  LYS A CG  1 
ATOM   3405 C  CD  . LYS A  1 439 ? 39.24131 1.89985   -34.77930 1.000 44.55168 ? 470  LYS A CD  1 
ATOM   3406 C  CE  . LYS A  1 439 ? 39.40593 3.39528   -35.01871 1.000 49.61673 ? 470  LYS A CE  1 
ATOM   3407 N  NZ  . LYS A  1 439 ? 40.75782 3.71727   -35.56158 1.000 51.21541 ? 470  LYS A NZ  1 
ATOM   3408 N  N   . SER A  1 440 ? 36.41485 -2.44715  -31.99579 1.000 23.05806 ? 471  SER A N   1 
ATOM   3409 C  CA  . SER A  1 440 ? 36.20390 -3.88584  -31.91546 1.000 25.76056 ? 471  SER A CA  1 
ATOM   3410 C  C   . SER A  1 440 ? 34.76228 -4.26630  -31.59974 1.000 23.70305 ? 471  SER A C   1 
ATOM   3411 O  O   . SER A  1 440 ? 34.44554 -5.45842  -31.60723 1.000 25.83914 ? 471  SER A O   1 
ATOM   3412 C  CB  . SER A  1 440 ? 37.11767 -4.49505  -30.84851 1.000 27.34762 ? 471  SER A CB  1 
ATOM   3413 O  OG  . SER A  1 440 ? 36.66251 -4.15435  -29.53848 1.000 27.08810 ? 471  SER A OG  1 
ATOM   3414 N  N   . PHE A  1 441 ? 33.89164 -3.29526  -31.32768 1.000 22.76057 ? 472  PHE A N   1 
ATOM   3415 C  CA  . PHE A  1 441 ? 32.55497 -3.60639  -30.82838 1.000 22.45127 ? 472  PHE A CA  1 
ATOM   3416 C  C   . PHE A  1 441 ? 31.67924 -4.23788  -31.90639 1.000 26.73826 ? 472  PHE A C   1 
ATOM   3417 O  O   . PHE A  1 441 ? 31.85422 -4.00406  -33.10576 1.000 26.72253 ? 472  PHE A O   1 
ATOM   3418 C  CB  . PHE A  1 441 ? 31.85022 -2.34889  -30.31895 1.000 20.34852 ? 472  PHE A CB  1 
ATOM   3419 C  CG  . PHE A  1 441 ? 32.42789 -1.78651  -29.05010 1.000 19.95879 ? 472  PHE A CG  1 
ATOM   3420 C  CD1 . PHE A  1 441 ? 33.52397 -2.36967  -28.44168 1.000 19.08052 ? 472  PHE A CD1 1 
ATOM   3421 C  CD2 . PHE A  1 441 ? 31.85802 -0.66307  -28.46718 1.000 19.22996 ? 472  PHE A CD2 1 
ATOM   3422 C  CE1 . PHE A  1 441 ? 34.04849 -1.84348  -27.26300 1.000 18.94552 ? 472  PHE A CE1 1 
ATOM   3423 C  CE2 . PHE A  1 441 ? 32.37900 -0.12861  -27.29288 1.000 20.10977 ? 472  PHE A CE2 1 
ATOM   3424 C  CZ  . PHE A  1 441 ? 33.46840 -0.71533  -26.68960 1.000 20.37853 ? 472  PHE A CZ  1 
ATOM   3425 N  N   . VAL A  1 442 ? 30.70310 -5.01377  -31.45575 1.000 21.26774 ? 473  VAL A N   1 
ATOM   3426 C  CA  . VAL A  1 442 ? 29.68889 -5.57410  -32.32613 1.000 19.82227 ? 473  VAL A CA  1 
ATOM   3427 C  C   . VAL A  1 442 ? 28.39008 -4.80252  -32.12707 1.000 22.40857 ? 473  VAL A C   1 
ATOM   3428 O  O   . VAL A  1 442 ? 28.24516 -4.01606  -31.19393 1.000 25.02181 ? 473  VAL A O   1 
ATOM   3429 C  CB  . VAL A  1 442 ? 29.48920 -7.08827  -32.07429 1.000 21.21019 ? 473  VAL A CB  1 
ATOM   3430 C  CG1 . VAL A  1 442 ? 30.79454 -7.83473  -32.26396 1.000 26.43466 ? 473  VAL A CG1 1 
ATOM   3431 C  CG2 . VAL A  1 442 ? 28.91615 -7.33805  -30.67654 1.000 20.76960 ? 473  VAL A CG2 1 
ATOM   3432 N  N   . LYS A  1 443 ? 27.43121 -5.01317  -33.02885 1.000 22.17927 ? 474  LYS A N   1 
ATOM   3433 C  CA  . LYS A  1 443 ? 26.11590 -4.42583  -32.84430 1.000 24.57093 ? 474  LYS A CA  1 
ATOM   3434 C  C   . LYS A  1 443 ? 25.38477 -5.12468  -31.70180 1.000 20.68263 ? 474  LYS A C   1 
ATOM   3435 O  O   . LYS A  1 443 ? 25.55052 -6.33021  -31.49321 1.000 22.69620 ? 474  LYS A O   1 
ATOM   3436 C  CB  . LYS A  1 443 ? 25.28806 -4.53424  -34.12328 1.000 30.70937 ? 474  LYS A CB  1 
ATOM   3437 N  N   . PRO A  1 444 ? 24.57596 -4.38764  -30.94103 1.000 20.93051 ? 475  PRO A N   1 
ATOM   3438 C  CA  . PRO A  1 444 ? 23.73111 -5.03340  -29.92665 1.000 22.03673 ? 475  PRO A CA  1 
ATOM   3439 C  C   . PRO A  1 444 ? 22.76651 -6.01626  -30.56607 1.000 21.96287 ? 475  PRO A C   1 
ATOM   3440 O  O   . PRO A  1 444 ? 22.20405 -5.75419  -31.63321 1.000 23.97153 ? 475  PRO A O   1 
ATOM   3441 C  CB  . PRO A  1 444 ? 22.97731 -3.86165  -29.28599 1.000 24.28498 ? 475  PRO A CB  1 
ATOM   3442 C  CG  . PRO A  1 444 ? 23.77673 -2.64591  -29.62293 1.000 27.50735 ? 475  PRO A CG  1 
ATOM   3443 C  CD  . PRO A  1 444 ? 24.42906 -2.92750  -30.94401 1.000 22.90106 ? 475  PRO A CD  1 
ATOM   3444 N  N   . LEU A  1 445 ? 22.56936 -7.15466  -29.89156 1.000 20.87015 ? 476  LEU A N   1 
ATOM   3445 C  CA  . LEU A  1 445 ? 21.58368 -8.13110  -30.34906 1.000 21.06928 ? 476  LEU A CA  1 
ATOM   3446 C  C   . LEU A  1 445 ? 20.16542 -7.65976  -30.07658 1.000 23.60260 ? 476  LEU A C   1 
ATOM   3447 O  O   . LEU A  1 445 ? 19.22956 -8.07562  -30.76568 1.000 25.04143 ? 476  LEU A O   1 
ATOM   3448 C  CB  . LEU A  1 445 ? 21.83083 -9.48494  -29.68175 1.000 20.63878 ? 476  LEU A CB  1 
ATOM   3449 C  CG  . LEU A  1 445 ? 23.15505 -10.12695 -30.07127 1.000 23.06635 ? 476  LEU A CG  1 
ATOM   3450 C  CD1 . LEU A  1 445 ? 23.46110 -11.27796 -29.13206 1.000 27.98471 ? 476  LEU A CD1 1 
ATOM   3451 C  CD2 . LEU A  1 445 ? 23.10943 -10.59879 -31.52533 1.000 26.33592 ? 476  LEU A CD2 1 
ATOM   3452 N  N   . TRP A  1 446 ? 19.98901 -6.81022  -29.07143 1.000 18.26582 ? 477  TRP A N   1 
ATOM   3453 C  CA  . TRP A  1 446 ? 18.71708 -6.17365  -28.77269 1.000 19.19600 ? 477  TRP A CA  1 
ATOM   3454 C  C   . TRP A  1 446 ? 19.04542 -4.82669  -28.16137 1.000 20.46981 ? 477  TRP A C   1 
ATOM   3455 O  O   . TRP A  1 446 ? 20.14876 -4.62171  -27.65119 1.000 19.49935 ? 477  TRP A O   1 
ATOM   3456 C  CB  . TRP A  1 446 ? 17.87091 -7.00206  -27.79586 1.000 19.00591 ? 477  TRP A CB  1 
ATOM   3457 C  CG  . TRP A  1 446 ? 18.62482 -7.32137  -26.52388 1.000 17.72482 ? 477  TRP A CG  1 
ATOM   3458 C  CD1 . TRP A  1 446 ? 18.74771 -6.52683  -25.41708 1.000 20.54483 ? 477  TRP A CD1 1 
ATOM   3459 C  CD2 . TRP A  1 446 ? 19.36029 -8.51596  -26.24741 1.000 18.20833 ? 477  TRP A CD2 1 
ATOM   3460 N  NE1 . TRP A  1 446 ? 19.52461 -7.16101  -24.46662 1.000 19.80074 ? 477  TRP A NE1 1 
ATOM   3461 C  CE2 . TRP A  1 446 ? 19.90921 -8.38403  -24.95684 1.000 19.47781 ? 477  TRP A CE2 1 
ATOM   3462 C  CE3 . TRP A  1 446 ? 19.60890 -9.69080  -26.97326 1.000 19.26408 ? 477  TRP A CE3 1 
ATOM   3463 C  CZ2 . TRP A  1 446 ? 20.69418 -9.38053  -24.37747 1.000 17.50035 ? 477  TRP A CZ2 1 
ATOM   3464 C  CZ3 . TRP A  1 446 ? 20.37730 -10.68030 -26.39890 1.000 20.05143 ? 477  TRP A CZ3 1 
ATOM   3465 C  CH2 . TRP A  1 446 ? 20.91604 -10.52112 -25.10849 1.000 19.58332 ? 477  TRP A CH2 1 
ATOM   3466 N  N   . VAL A  1 447 ? 18.08907 -3.90496  -28.23066 1.000 17.41577 ? 478  VAL A N   1 
ATOM   3467 C  CA  . VAL A  1 447 ? 18.22425 -2.63434  -27.52328 1.000 17.62712 ? 478  VAL A CA  1 
ATOM   3468 C  C   . VAL A  1 447 ? 17.13645 -2.61765  -26.45796 1.000 18.36961 ? 478  VAL A C   1 
ATOM   3469 O  O   . VAL A  1 447 ? 16.49139 -3.64270  -26.21759 1.000 22.55421 ? 478  VAL A O   1 
ATOM   3470 C  CB  . VAL A  1 447 ? 18.15271 -1.43136  -28.48174 1.000 20.95987 ? 478  VAL A CB  1 
ATOM   3471 C  CG1 . VAL A  1 447 ? 19.32556 -1.48387  -29.44763 1.000 19.40492 ? 478  VAL A CG1 1 
ATOM   3472 C  CG2 . VAL A  1 447 ? 16.84941 -1.41204  -29.24077 1.000 20.31641 ? 478  VAL A CG2 1 
ATOM   3473 N  N   . TYR A  1 448 ? 16.92926 -1.48142  -25.78899 1.000 18.25234 ? 479  TYR A N   1 
ATOM   3474 C  CA  . TYR A  1 448 ? 15.99777 -1.45572  -24.66565 1.000 18.42185 ? 479  TYR A CA  1 
ATOM   3475 C  C   . TYR A  1 448 ? 14.69496 -0.73785  -24.97764 1.000 17.24874 ? 479  TYR A C   1 
ATOM   3476 O  O   . TYR A  1 448 ? 13.62166 -1.25284  -24.65023 1.000 22.49562 ? 479  TYR A O   1 
ATOM   3477 C  CB  . TYR A  1 448 ? 16.65950 -0.81584  -23.43039 1.000 18.45736 ? 479  TYR A CB  1 
ATOM   3478 C  CG  . TYR A  1 448 ? 15.91597 -1.10810  -22.14338 1.000 18.97324 ? 479  TYR A CG  1 
ATOM   3479 C  CD1 . TYR A  1 448 ? 16.01335 -2.36141  -21.53068 1.000 19.81699 ? 479  TYR A CD1 1 
ATOM   3480 C  CD2 . TYR A  1 448 ? 15.12043 -0.13738  -21.54020 1.000 20.69544 ? 479  TYR A CD2 1 
ATOM   3481 C  CE1 . TYR A  1 448 ? 15.33535 -2.63293  -20.35597 1.000 19.93231 ? 479  TYR A CE1 1 
ATOM   3482 C  CE2 . TYR A  1 448 ? 14.43274 -0.40555  -20.36750 1.000 23.20921 ? 479  TYR A CE2 1 
ATOM   3483 C  CZ  . TYR A  1 448 ? 14.55141 -1.65298  -19.77909 1.000 20.82117 ? 479  TYR A CZ  1 
ATOM   3484 O  OH  . TYR A  1 448 ? 13.88093 -1.92518  -18.59680 1.000 24.35214 ? 479  TYR A OH  1 
ATOM   3485 N  N   . SER A  1 449 ? 14.74090 0.43705   -25.60206 1.000 17.19997 ? 480  SER A N   1 
ATOM   3486 C  CA  . SER A  1 449 ? 13.53239 1.20252   -25.85413 1.000 19.19007 ? 480  SER A CA  1 
ATOM   3487 C  C   . SER A  1 449 ? 13.29154 1.35034   -27.34920 1.000 20.92840 ? 480  SER A C   1 
ATOM   3488 O  O   . SER A  1 449 ? 14.18390 1.12566   -28.16766 1.000 19.09882 ? 480  SER A O   1 
ATOM   3489 C  CB  . SER A  1 449 ? 13.60928 2.60231   -25.22254 1.000 17.75269 ? 480  SER A CB  1 
ATOM   3490 O  OG  . SER A  1 449 ? 14.67298 3.34749   -25.79613 1.000 20.03699 ? 480  SER A OG  1 
ATOM   3491 N  N   . VAL A  1 450 ? 12.05904 1.73279   -27.69133 1.000 20.32519 ? 481  VAL A N   1 
ATOM   3492 C  CA  . VAL A  1 450 ? 11.75745 2.11551   -29.06950 1.000 20.41111 ? 481  VAL A CA  1 
ATOM   3493 C  C   . VAL A  1 450 ? 12.66950 3.24925   -29.51859 1.000 21.91019 ? 481  VAL A C   1 
ATOM   3494 O  O   . VAL A  1 450 ? 13.16854 3.25388   -30.65470 1.000 20.78178 ? 481  VAL A O   1 
ATOM   3495 C  CB  . VAL A  1 450 ? 10.27058 2.49334   -29.20099 1.000 19.68701 ? 481  VAL A CB  1 
ATOM   3496 C  CG1 . VAL A  1 450 ? 9.98193  3.08524   -30.57681 1.000 21.78407 ? 481  VAL A CG1 1 
ATOM   3497 C  CG2 . VAL A  1 450 ? 9.40124  1.26773   -28.93052 1.000 21.46128 ? 481  VAL A CG2 1 
ATOM   3498 N  N   . LYS A  1 451 ? 12.92315 4.21539   -28.62911 1.000 18.19688 ? 482  LYS A N   1 
ATOM   3499 C  CA  . LYS A  1 451 ? 13.84615 5.29514   -28.95870 1.000 19.97212 ? 482  LYS A CA  1 
ATOM   3500 C  C   . LYS A  1 451 ? 15.20718 4.73931   -29.36907 1.000 20.09371 ? 482  LYS A C   1 
ATOM   3501 O  O   . LYS A  1 451 ? 15.78925 5.18391   -30.36322 1.000 19.80190 ? 482  LYS A O   1 
ATOM   3502 C  CB  . LYS A  1 451 ? 13.98671 6.24784   -27.76767 1.000 18.65118 ? 482  LYS A CB  1 
ATOM   3503 C  CG  . LYS A  1 451 ? 14.92500 7.42523   -28.02238 1.000 20.15853 ? 482  LYS A CG  1 
ATOM   3504 C  CD  . LYS A  1 451 ? 14.32761 8.37593   -29.03728 1.000 17.84608 ? 482  LYS A CD  1 
ATOM   3505 C  CE  . LYS A  1 451 ? 15.24092 9.58369   -29.25219 1.000 23.35795 ? 482  LYS A CE  1 
ATOM   3506 N  NZ  . LYS A  1 451 ? 14.67436 10.54227  -30.24832 1.000 22.79053 ? 482  LYS A NZ  1 
ATOM   3507 N  N   . ASP A  1 452 ? 15.72911 3.76173   -28.61352 1.000 18.63133 ? 483  ASP A N   1 
ATOM   3508 C  CA  . ASP A  1 452 ? 17.00308 3.12907   -28.97272 1.000 18.91614 ? 483  ASP A CA  1 
ATOM   3509 C  C   . ASP A  1 452 ? 16.96351 2.59326   -30.39747 1.000 19.10416 ? 483  ASP A C   1 
ATOM   3510 O  O   . ASP A  1 452 ? 17.90572 2.78449   -31.18010 1.000 20.67679 ? 483  ASP A O   1 
ATOM   3511 C  CB  . ASP A  1 452 ? 17.33702 1.95689   -28.03840 1.000 19.42806 ? 483  ASP A CB  1 
ATOM   3512 C  CG  . ASP A  1 452 ? 17.63510 2.37017   -26.60571 1.000 19.95345 ? 483  ASP A CG  1 
ATOM   3513 O  OD1 . ASP A  1 452 ? 18.06413 3.51722   -26.36379 1.000 20.59907 ? 483  ASP A OD1 1 
ATOM   3514 O  OD2 . ASP A  1 452 ? 17.46826 1.48889   -25.73522 1.000 20.63417 ? 483  ASP A OD2 1 
ATOM   3515 N  N   . LYS A  1 453 ? 15.88734 1.87601   -30.72640 1.000 19.69864 ? 484  LYS A N   1 
ATOM   3516 C  CA  . LYS A  1 453 ? 15.78516 1.22621   -32.02921 1.000 19.54180 ? 484  LYS A CA  1 
ATOM   3517 C  C   . LYS A  1 453 ? 15.82963 2.25304   -33.14996 1.000 20.59574 ? 484  LYS A C   1 
ATOM   3518 O  O   . LYS A  1 453 ? 16.55653 2.08368   -34.13580 1.000 22.30321 ? 484  LYS A O   1 
ATOM   3519 C  CB  . LYS A  1 453 ? 14.50002 0.40286   -32.10443 1.000 20.66478 ? 484  LYS A CB  1 
ATOM   3520 C  CG  . LYS A  1 453 ? 14.32041 -0.30626  -33.44898 1.000 23.93064 ? 484  LYS A CG  1 
ATOM   3521 C  CD  . LYS A  1 453 ? 13.22543 -1.36037  -33.34441 1.000 30.19311 ? 484  LYS A CD  1 
ATOM   3522 C  CE  . LYS A  1 453 ? 13.07592 -2.15592  -34.64062 1.000 38.05889 ? 484  LYS A CE  1 
ATOM   3523 N  NZ  . LYS A  1 453 ? 12.36058 -1.36796  -35.67736 1.000 44.81238 ? 484  LYS A NZ  1 
ATOM   3524 N  N   . GLU A  1 454 ? 15.06712 3.33803   -33.00441 1.000 20.24479 ? 485  GLU A N   1 
ATOM   3525 C  CA  . GLU A  1 454 ? 15.09779 4.39678   -34.00914 1.000 21.92566 ? 485  GLU A CA  1 
ATOM   3526 C  C   . GLU A  1 454 ? 16.49533 4.97838   -34.15718 1.000 22.08976 ? 485  GLU A C   1 
ATOM   3527 O  O   . GLU A  1 454 ? 16.95896 5.22803   -35.27518 1.000 20.39698 ? 485  GLU A O   1 
ATOM   3528 C  CB  . GLU A  1 454 ? 14.09925 5.49365   -33.64335 1.000 21.17596 ? 485  GLU A CB  1 
ATOM   3529 C  CG  . GLU A  1 454 ? 12.66180 5.00802   -33.60106 1.000 22.72222 ? 485  GLU A CG  1 
ATOM   3530 C  CD  . GLU A  1 454 ? 11.67902 6.09975   -33.19884 1.000 26.32602 ? 485  GLU A CD  1 
ATOM   3531 O  OE1 . GLU A  1 454 ? 12.12878 7.19363   -32.80497 1.000 27.08037 ? 485  GLU A OE1 1 
ATOM   3532 O  OE2 . GLU A  1 454 ? 10.45512 5.85847   -33.27915 1.000 29.93253 ? 485  GLU A OE2 1 
ATOM   3533 N  N   . LEU A  1 455 ? 17.18605 5.20184   -33.03646 1.000 19.34134 ? 486  LEU A N   1 
ATOM   3534 C  CA  . LEU A  1 455 ? 18.49854 5.83199   -33.09756 1.000 20.64172 ? 486  LEU A CA  1 
ATOM   3535 C  C   . LEU A  1 455 ? 19.52873 4.92911   -33.76074 1.000 20.69971 ? 486  LEU A C   1 
ATOM   3536 O  O   . LEU A  1 455 ? 20.35741 5.40244   -34.55202 1.000 20.30100 ? 486  LEU A O   1 
ATOM   3537 C  CB  . LEU A  1 455 ? 18.95854 6.20935   -31.69181 1.000 23.61417 ? 486  LEU A CB  1 
ATOM   3538 C  CG  . LEU A  1 455 ? 18.16509 7.31090   -30.98917 1.000 22.56260 ? 486  LEU A CG  1 
ATOM   3539 C  CD1 . LEU A  1 455 ? 18.58818 7.39087   -29.52316 1.000 23.56345 ? 486  LEU A CD1 1 
ATOM   3540 C  CD2 . LEU A  1 455 ? 18.35966 8.65816   -31.68838 1.000 25.45624 ? 486  LEU A CD2 1 
ATOM   3541 N  N   . TRP A  1 456 ? 19.52151 3.63618   -33.42715 1.000 19.67741 ? 487  TRP A N   1 
ATOM   3542 C  CA  . TRP A  1 456 ? 20.46872 2.72652   -34.06532 1.000 21.19986 ? 487  TRP A CA  1 
ATOM   3543 C  C   . TRP A  1 456 ? 20.15334 2.57199   -35.54621 1.000 21.44842 ? 487  TRP A C   1 
ATOM   3544 O  O   . TRP A  1 456 ? 21.06896 2.47648   -36.37062 1.000 21.36274 ? 487  TRP A O   1 
ATOM   3545 C  CB  . TRP A  1 456 ? 20.46591 1.36673   -33.36174 1.000 20.65281 ? 487  TRP A CB  1 
ATOM   3546 C  CG  . TRP A  1 456 ? 21.26745 1.38825   -32.08020 1.000 20.71917 ? 487  TRP A CG  1 
ATOM   3547 C  CD1 . TRP A  1 456 ? 20.83813 1.81579   -30.84714 1.000 19.48886 ? 487  TRP A CD1 1 
ATOM   3548 C  CD2 . TRP A  1 456 ? 22.62760 0.97361   -31.91210 1.000 19.66396 ? 487  TRP A CD2 1 
ATOM   3549 N  NE1 . TRP A  1 456 ? 21.85679 1.69274   -29.92888 1.000 18.16288 ? 487  TRP A NE1 1 
ATOM   3550 C  CE2 . TRP A  1 456 ? 22.96191 1.17382   -30.55405 1.000 18.17030 ? 487  TRP A CE2 1 
ATOM   3551 C  CE3 . TRP A  1 456 ? 23.59707 0.43945   -32.77511 1.000 19.44459 ? 487  TRP A CE3 1 
ATOM   3552 C  CZ2 . TRP A  1 456 ? 24.23047 0.87508   -30.04258 1.000 19.03992 ? 487  TRP A CZ2 1 
ATOM   3553 C  CZ3 . TRP A  1 456 ? 24.85280 0.13279   -32.26488 1.000 19.62794 ? 487  TRP A CZ3 1 
ATOM   3554 C  CH2 . TRP A  1 456 ? 25.15874 0.35784   -30.90857 1.000 20.17082 ? 487  TRP A CH2 1 
ATOM   3555 N  N   . GLU A  1 457 ? 18.86756 2.58127   -35.90315 1.000 21.69136 ? 488  GLU A N   1 
ATOM   3556 C  CA  . GLU A  1 457 ? 18.48472 2.37348   -37.29760 1.000 23.15762 ? 488  GLU A CA  1 
ATOM   3557 C  C   . GLU A  1 457 ? 18.75501 3.59338   -38.17134 1.000 25.34626 ? 488  GLU A C   1 
ATOM   3558 O  O   . GLU A  1 457 ? 18.83832 3.45345   -39.39712 1.000 23.76862 ? 488  GLU A O   1 
ATOM   3559 C  CB  . GLU A  1 457 ? 17.01195 1.95885   -37.37473 1.000 24.33621 ? 488  GLU A CB  1 
ATOM   3560 C  CG  . GLU A  1 457 ? 16.81248 0.50380   -36.98176 1.000 28.33486 ? 488  GLU A CG  1 
ATOM   3561 C  CD  . GLU A  1 457 ? 15.37273 0.03259   -37.05637 1.000 30.11822 ? 488  GLU A CD  1 
ATOM   3562 O  OE1 . GLU A  1 457 ? 14.46964 0.84932   -37.31372 1.000 33.76237 ? 488  GLU A OE1 1 
ATOM   3563 O  OE2 . GLU A  1 457 ? 15.14777 -1.17368  -36.84840 1.000 34.98871 ? 488  GLU A OE2 1 
ATOM   3564 N  N   . SER A  1 458 ? 18.90895 4.77606   -37.58022 1.000 22.28721 ? 489  SER A N   1 
ATOM   3565 C  CA  . SER A  1 458 ? 19.29618 5.96667   -38.32529 1.000 23.98500 ? 489  SER A CA  1 
ATOM   3566 C  C   . SER A  1 458 ? 20.79945 6.20272   -38.34170 1.000 23.96375 ? 489  SER A C   1 
ATOM   3567 O  O   . SER A  1 458 ? 21.27623 7.03713   -39.12143 1.000 24.15352 ? 489  SER A O   1 
ATOM   3568 C  CB  . SER A  1 458 ? 18.61021 7.20309   -37.73795 1.000 26.12049 ? 489  SER A CB  1 
ATOM   3569 O  OG  . SER A  1 458 ? 19.12303 7.47509   -36.43979 1.000 24.35265 ? 489  SER A OG  1 
ATOM   3570 N  N   . GLY A  1 459 ? 21.56449 5.50772   -37.50364 1.000 19.31010 ? 490  GLY A N   1 
ATOM   3571 C  CA  . GLY A  1 459 ? 22.96549 5.80787   -37.36437 1.000 21.71538 ? 490  GLY A CA  1 
ATOM   3572 C  C   . GLY A  1 459 ? 23.26292 6.89338   -36.35755 1.000 22.95369 ? 490  GLY A C   1 
ATOM   3573 O  O   . GLY A  1 459 ? 24.43698 7.20107   -36.13307 1.000 24.39186 ? 490  GLY A O   1 
ATOM   3574 N  N   . GLN A  1 460 ? 22.23238 7.48247   -35.74659 1.000 21.22259 ? 491  GLN A N   1 
ATOM   3575 C  CA  . GLN A  1 460 ? 22.46015 8.44958   -34.67828 1.000 21.93084 ? 491  GLN A CA  1 
ATOM   3576 C  C   . GLN A  1 460 ? 23.11461 7.79525   -33.47221 1.000 22.65576 ? 491  GLN A C   1 
ATOM   3577 O  O   . GLN A  1 460 ? 23.87730 8.44793   -32.74593 1.000 24.96553 ? 491  GLN A O   1 
ATOM   3578 C  CB  . GLN A  1 460 ? 21.14050 9.10529   -34.28295 1.000 25.04425 ? 491  GLN A CB  1 
ATOM   3579 C  CG  . GLN A  1 460 ? 20.57982 10.03854  -35.34225 1.000 30.44074 ? 491  GLN A CG  1 
ATOM   3580 C  CD  . GLN A  1 460 ? 19.19688 10.54051  -34.97774 1.000 35.89842 ? 491  GLN A CD  1 
ATOM   3581 O  OE1 . GLN A  1 460 ? 19.05202 11.59360  -34.35691 1.000 40.13076 ? 491  GLN A OE1 1 
ATOM   3582 N  NE2 . GLN A  1 460 ? 18.17169 9.78228   -35.35305 1.000 32.20011 ? 491  GLN A NE2 1 
ATOM   3583 N  N   . MET A  1 461 ? 22.82492 6.52569   -33.24143 1.000 20.60781 ? 492  MET A N   1 
ATOM   3584 C  CA  . MET A  1 461 ? 23.58719 5.66198   -32.36877 1.000 18.70791 ? 492  MET A CA  1 
ATOM   3585 C  C   . MET A  1 461 ? 24.29623 4.60592   -33.20943 1.000 20.01885 ? 492  MET A C   1 
ATOM   3586 O  O   . MET A  1 461 ? 23.75430 4.16305   -34.22855 1.000 20.43810 ? 492  MET A O   1 
ATOM   3587 C  CB  . MET A  1 461 ? 22.69594 4.97256   -31.32471 1.000 20.87913 ? 492  MET A CB  1 
ATOM   3588 C  CG  . MET A  1 461 ? 22.19418 5.91880   -30.23035 1.000 20.11133 ? 492  MET A CG  1 
ATOM   3589 S  SD  . MET A  1 461 ? 23.51590 6.55924   -29.18828 1.000 20.44603 ? 492  MET A SD  1 
ATOM   3590 C  CE  . MET A  1 461 ? 23.84989 5.13878   -28.14671 1.000 18.80698 ? 492  MET A CE  1 
ATOM   3591 N  N   . PRO A  1 462 ? 25.50547 4.18888   -32.82016 1.000 19.69740 ? 493  PRO A N   1 
ATOM   3592 C  CA  . PRO A  1 462 ? 26.23077 4.62798   -31.61924 1.000 19.64245 ? 493  PRO A CA  1 
ATOM   3593 C  C   . PRO A  1 462 ? 27.06097 5.88327   -31.81417 1.000 21.89601 ? 493  PRO A C   1 
ATOM   3594 O  O   . PRO A  1 462 ? 27.40812 6.51103   -30.82108 1.000 18.80412 ? 493  PRO A O   1 
ATOM   3595 C  CB  . PRO A  1 462 ? 27.12576 3.43002   -31.31321 1.000 20.14320 ? 493  PRO A CB  1 
ATOM   3596 C  CG  . PRO A  1 462 ? 27.44888 2.87242   -32.68983 1.000 20.16939 ? 493  PRO A CG  1 
ATOM   3597 C  CD  . PRO A  1 462 ? 26.18870 3.06851   -33.49527 1.000 21.12932 ? 493  PRO A CD  1 
ATOM   3598 N  N   . ASN A  1 463 ? 27.39999 6.23514   -33.05526 1.000 19.17378 ? 494  ASN A N   1 
ATOM   3599 C  CA  . ASN A  1 463 ? 28.22056 7.39925   -33.38201 1.000 22.85060 ? 494  ASN A CA  1 
ATOM   3600 C  C   . ASN A  1 463 ? 29.41561 7.53016   -32.43033 1.000 19.70511 ? 494  ASN A C   1 
ATOM   3601 O  O   . ASN A  1 463 ? 29.58113 8.52400   -31.72477 1.000 22.66117 ? 494  ASN A O   1 
ATOM   3602 C  CB  . ASN A  1 463 ? 27.37254 8.67037   -33.38505 1.000 21.66340 ? 494  ASN A CB  1 
ATOM   3603 C  CG  . ASN A  1 463 ? 28.04305 9.81705   -34.12508 1.000 24.33917 ? 494  ASN A CG  1 
ATOM   3604 O  OD1 . ASN A  1 463 ? 29.16801 9.68698   -34.61847 1.000 23.90738 ? 494  ASN A OD1 1 
ATOM   3605 N  ND2 . ASN A  1 463 ? 27.35301 10.94486  -34.20423 1.000 26.34922 ? 494  ASN A ND2 1 
ATOM   3606 N  N   . TYR A  1 464 ? 30.25451 6.48778   -32.41798 1.000 19.74038 ? 495  TYR A N   1 
ATOM   3607 C  CA  . TYR A  1 464 ? 31.46080 6.54128   -31.59575 1.000 20.15040 ? 495  TYR A CA  1 
ATOM   3608 C  C   . TYR A  1 464 ? 32.34431 7.71936   -31.98315 1.000 21.33988 ? 495  TYR A C   1 
ATOM   3609 O  O   . TYR A  1 464 ? 33.01677 8.29470   -31.12156 1.000 21.62554 ? 495  TYR A O   1 
ATOM   3610 C  CB  . TYR A  1 464 ? 32.25812 5.23434   -31.70021 1.000 20.76411 ? 495  TYR A CB  1 
ATOM   3611 C  CG  . TYR A  1 464 ? 31.48078 4.02545   -31.24121 1.000 21.44512 ? 495  TYR A CG  1 
ATOM   3612 C  CD1 . TYR A  1 464 ? 30.97183 3.95047   -29.94587 1.000 20.27241 ? 495  TYR A CD1 1 
ATOM   3613 C  CD2 . TYR A  1 464 ? 31.22121 2.97036   -32.10875 1.000 20.38483 ? 495  TYR A CD2 1 
ATOM   3614 C  CE1 . TYR A  1 464 ? 30.23422 2.84517   -29.53391 1.000 17.68893 ? 495  TYR A CE1 1 
ATOM   3615 C  CE2 . TYR A  1 464 ? 30.50183 1.85926   -31.70402 1.000 19.75974 ? 495  TYR A CE2 1 
ATOM   3616 C  CZ  . TYR A  1 464 ? 30.00492 1.79788   -30.41392 1.000 20.71494 ? 495  TYR A CZ  1 
ATOM   3617 O  OH  . TYR A  1 464 ? 29.25918 0.70435   -30.01988 1.000 20.77284 ? 495  TYR A OH  1 
ATOM   3618 N  N   . GLU A  1 465 ? 32.34791 8.09926   -33.26424 1.000 22.59258 ? 496  GLU A N   1 
ATOM   3619 C  CA  . GLU A  1 465 ? 33.20498 9.19224   -33.71277 1.000 24.41906 ? 496  GLU A CA  1 
ATOM   3620 C  C   . GLU A  1 465 ? 32.90661 10.47006  -32.93643 1.000 22.94433 ? 496  GLU A C   1 
ATOM   3621 O  O   . GLU A  1 465 ? 33.82342 11.15189  -32.46015 1.000 25.67955 ? 496  GLU A O   1 
ATOM   3622 C  CB  . GLU A  1 465 ? 33.01971 9.42070   -35.21496 1.000 27.94265 ? 496  GLU A CB  1 
ATOM   3623 N  N   . ALA A  1 466 ? 31.61966 10.79585  -32.77950 1.000 21.80730 ? 497  ALA A N   1 
ATOM   3624 C  CA  . ALA A  1 466 ? 31.24451 11.98819  -32.02850 1.000 21.49184 ? 497  ALA A CA  1 
ATOM   3625 C  C   . ALA A  1 466 ? 31.60311 11.85211  -30.55419 1.000 21.66237 ? 497  ALA A C   1 
ATOM   3626 O  O   . ALA A  1 466 ? 32.00651 12.83544  -29.92278 1.000 19.29470 ? 497  ALA A O   1 
ATOM   3627 C  CB  . ALA A  1 466 ? 29.75488 12.26749  -32.19522 1.000 23.50975 ? 497  ALA A CB  1 
ATOM   3628 N  N   . THR A  1 467 ? 31.50047 10.63900  -30.00508 1.000 20.21990 ? 498  THR A N   1 
ATOM   3629 C  CA  . THR A  1 467 ? 31.84129 10.43604  -28.60004 1.000 20.28503 ? 498  THR A CA  1 
ATOM   3630 C  C   . THR A  1 467 ? 33.26857 10.87134  -28.30465 1.000 18.94899 ? 498  THR A C   1 
ATOM   3631 O  O   . THR A  1 467 ? 33.55020 11.42703  -27.23627 1.000 18.65512 ? 498  THR A O   1 
ATOM   3632 C  CB  . THR A  1 467 ? 31.62503 8.96757   -28.23167 1.000 19.21505 ? 498  THR A CB  1 
ATOM   3633 O  OG1 . THR A  1 467 ? 30.22339 8.68917   -28.25952 1.000 19.21334 ? 498  THR A OG1 1 
ATOM   3634 C  CG2 . THR A  1 467 ? 32.18749 8.64033   -26.84280 1.000 18.97052 ? 498  THR A CG2 1 
ATOM   3635 N  N   . PHE A  1 468 ? 34.18961 10.64558  -29.24239 1.000 18.51410 ? 499  PHE A N   1 
ATOM   3636 C  CA  . PHE A  1 468 ? 35.59632 10.93344  -28.99823 1.000 19.89064 ? 499  PHE A CA  1 
ATOM   3637 C  C   . PHE A  1 468 ? 36.04523 12.27660  -29.58406 1.000 20.10515 ? 499  PHE A C   1 
ATOM   3638 O  O   . PHE A  1 468 ? 37.24939 12.55016  -29.64503 1.000 22.40662 ? 499  PHE A O   1 
ATOM   3639 C  CB  . PHE A  1 468 ? 36.42955 9.74991   -29.49425 1.000 18.86360 ? 499  PHE A CB  1 
ATOM   3640 C  CG  . PHE A  1 468 ? 36.09710 8.48181   -28.74816 1.000 17.21387 ? 499  PHE A CG  1 
ATOM   3641 C  CD1 . PHE A  1 468 ? 36.42138 8.36856   -27.40589 1.000 21.37382 ? 499  PHE A CD1 1 
ATOM   3642 C  CD2 . PHE A  1 468 ? 35.37585 7.45972   -29.34643 1.000 20.49132 ? 499  PHE A CD2 1 
ATOM   3643 C  CE1 . PHE A  1 468 ? 36.07588 7.23091   -26.68051 1.000 18.83907 ? 499  PHE A CE1 1 
ATOM   3644 C  CE2 . PHE A  1 468 ? 35.03436 6.30295   -28.63403 1.000 21.09854 ? 499  PHE A CE2 1 
ATOM   3645 C  CZ  . PHE A  1 468 ? 35.38528 6.19376   -27.29680 1.000 19.79928 ? 499  PHE A CZ  1 
ATOM   3646 N  N   . GLU A  1 469 ? 35.10138 13.14206  -29.94888 1.000 22.13124 ? 500  GLU A N   1 
ATOM   3647 C  CA  . GLU A  1 469 ? 35.42668 14.55401  -30.13661 1.000 19.72039 ? 500  GLU A CA  1 
ATOM   3648 C  C   . GLU A  1 469 ? 35.96184 15.14140  -28.83895 1.000 18.68227 ? 500  GLU A C   1 
ATOM   3649 O  O   . GLU A  1 469 ? 35.56542 14.73506  -27.74790 1.000 21.02074 ? 500  GLU A O   1 
ATOM   3650 C  CB  . GLU A  1 469 ? 34.19115 15.33081  -30.58939 1.000 19.99824 ? 500  GLU A CB  1 
ATOM   3651 C  CG  . GLU A  1 469 ? 33.77593 14.97031  -32.00108 1.000 22.56290 ? 500  GLU A CG  1 
ATOM   3652 C  CD  . GLU A  1 469 ? 32.40224 15.46654  -32.38349 1.000 24.16299 ? 500  GLU A CD  1 
ATOM   3653 O  OE1 . GLU A  1 469 ? 31.58983 15.79111  -31.48792 1.000 22.59105 ? 500  GLU A OE1 1 
ATOM   3654 O  OE2 . GLU A  1 469 ? 32.12217 15.52244  -33.60395 1.000 26.46979 ? 500  GLU A OE2 1 
ATOM   3655 N  N   . VAL A  1 470 ? 36.89292 16.09264  -28.95571 1.000 19.99801 ? 501  VAL A N   1 
ATOM   3656 C  CA  . VAL A  1 470 ? 37.47705 16.72108  -27.77147 1.000 20.49924 ? 501  VAL A CA  1 
ATOM   3657 C  C   . VAL A  1 470 ? 37.47535 18.24101  -27.90902 1.000 20.22630 ? 501  VAL A C   1 
ATOM   3658 O  O   . VAL A  1 470 ? 36.78075 18.94137  -27.16297 1.000 21.95574 ? 501  VAL A O   1 
ATOM   3659 C  CB  . VAL A  1 470 ? 38.90200 16.19668  -27.50079 1.000 20.56995 ? 501  VAL A CB  1 
ATOM   3660 C  CG1 . VAL A  1 470 ? 39.51789 16.92100  -26.30041 1.000 21.97961 ? 501  VAL A CG1 1 
ATOM   3661 C  CG2 . VAL A  1 470 ? 38.88865 14.70386  -27.24591 1.000 24.01264 ? 501  VAL A CG2 1 
ATOM   3662 N  N   . ASP A  1 471 ? 38.24229 18.76842  -28.86908 1.000 20.00922 ? 502  ASP A N   1 
ATOM   3663 C  CA  . ASP A  1 471 ? 38.47794 20.21099  -28.91060 1.000 20.23196 ? 502  ASP A CA  1 
ATOM   3664 C  C   . ASP A  1 471 ? 37.19647 20.99788  -29.14246 1.000 21.08395 ? 502  ASP A C   1 
ATOM   3665 O  O   . ASP A  1 471 ? 37.00784 22.06611  -28.54924 1.000 23.58430 ? 502  ASP A O   1 
ATOM   3666 C  CB  . ASP A  1 471 ? 39.48589 20.56365  -30.00557 1.000 21.72833 ? 502  ASP A CB  1 
ATOM   3667 C  CG  . ASP A  1 471 ? 40.86607 20.03995  -29.71443 1.000 30.63002 ? 502  ASP A CG  1 
ATOM   3668 O  OD1 . ASP A  1 471 ? 41.14307 19.70500  -28.54137 1.000 31.07934 ? 502  ASP A OD1 1 
ATOM   3669 O  OD2 . ASP A  1 471 ? 41.67333 19.97960  -30.66490 1.000 33.88675 ? 502  ASP A OD2 1 
ATOM   3670 N  N   . LYS A  1 472 ? 36.32825 20.52038  -30.03518 1.000 19.39830 ? 503  LYS A N   1 
ATOM   3671 C  CA  . LYS A  1 472 ? 35.14441 21.30440  -30.36720 1.000 22.28639 ? 503  LYS A CA  1 
ATOM   3672 C  C   . LYS A  1 472 ? 34.17879 21.41027  -29.19831 1.000 20.12628 ? 503  LYS A C   1 
ATOM   3673 O  O   . LYS A  1 472 ? 33.29471 22.27391  -29.22315 1.000 19.79926 ? 503  LYS A O   1 
ATOM   3674 C  CB  . LYS A  1 472 ? 34.42334 20.71556  -31.58346 1.000 23.96237 ? 503  LYS A CB  1 
ATOM   3675 C  CG  . LYS A  1 472 ? 33.82990 19.33169  -31.35939 1.000 24.61462 ? 503  LYS A CG  1 
ATOM   3676 C  CD  . LYS A  1 472 ? 32.94273 18.90729  -32.52973 1.000 22.69575 ? 503  LYS A CD  1 
ATOM   3677 C  CE  . LYS A  1 472 ? 33.75710 18.66126  -33.81008 1.000 23.20056 ? 503  LYS A CE  1 
ATOM   3678 N  NZ  . LYS A  1 472 ? 32.86936 18.10320  -34.88488 1.000 25.11023 ? 503  LYS A NZ  1 
ATOM   3679 N  N   . LEU A  1 473 ? 34.34709 20.57458  -28.17093 1.000 19.39198 ? 504  LEU A N   1 
ATOM   3680 C  CA  . LEU A  1 473 ? 33.47281 20.64821  -27.00953 1.000 19.98162 ? 504  LEU A CA  1 
ATOM   3681 C  C   . LEU A  1 473 ? 33.84217 21.80044  -26.08925 1.000 19.91367 ? 504  LEU A C   1 
ATOM   3682 O  O   . LEU A  1 473 ? 33.00424 22.22334  -25.28709 1.000 18.44009 ? 504  LEU A O   1 
ATOM   3683 C  CB  . LEU A  1 473 ? 33.52152 19.33480  -26.22472 1.000 16.71108 ? 504  LEU A CB  1 
ATOM   3684 C  CG  . LEU A  1 473 ? 33.27443 18.05300  -27.03343 1.000 16.10349 ? 504  LEU A CG  1 
ATOM   3685 C  CD1 . LEU A  1 473 ? 33.35967 16.81486  -26.13644 1.000 20.30399 ? 504  LEU A CD1 1 
ATOM   3686 C  CD2 . LEU A  1 473 ? 31.93576 18.09897  -27.75215 1.000 21.34054 ? 504  LEU A CD2 1 
ATOM   3687 N  N   . VAL A  1 474 ? 35.06478 22.31765  -26.19491 1.000 21.65237 ? 505  VAL A N   1 
ATOM   3688 C  CA  . VAL A  1 474 ? 35.53650 23.36814  -25.30244 1.000 22.09549 ? 505  VAL A CA  1 
ATOM   3689 C  C   . VAL A  1 474 ? 35.92920 24.64515  -26.03460 1.000 22.98272 ? 505  VAL A C   1 
ATOM   3690 O  O   . VAL A  1 474 ? 35.98863 25.71188  -25.39930 1.000 23.72223 ? 505  VAL A O   1 
ATOM   3691 C  CB  . VAL A  1 474 ? 36.71358 22.87229  -24.43777 1.000 24.61781 ? 505  VAL A CB  1 
ATOM   3692 C  CG1 . VAL A  1 474 ? 36.26501 21.74923  -23.50214 1.000 23.69256 ? 505  VAL A CG1 1 
ATOM   3693 C  CG2 . VAL A  1 474 ? 37.87234 22.40475  -25.31659 1.000 25.40773 ? 505  VAL A CG2 1 
ATOM   3694 N  N   . ASP A  1 475 ? 36.19309 24.58889  -27.33592 1.000 23.32147 ? 506  ASP A N   1 
ATOM   3695 C  CA  . ASP A  1 475 ? 36.57046 25.78637  -28.07675 1.000 22.03412 ? 506  ASP A CA  1 
ATOM   3696 C  C   . ASP A  1 475 ? 35.36659 26.68926  -28.32389 1.000 21.18510 ? 506  ASP A C   1 
ATOM   3697 O  O   . ASP A  1 475 ? 34.25033 26.21899  -28.56945 1.000 21.85321 ? 506  ASP A O   1 
ATOM   3698 C  CB  . ASP A  1 475 ? 37.20644 25.40536  -29.41730 1.000 21.96233 ? 506  ASP A CB  1 
ATOM   3699 C  CG  . ASP A  1 475 ? 38.57965 24.77594  -29.26394 1.000 27.71841 ? 506  ASP A CG  1 
ATOM   3700 O  OD1 . ASP A  1 475 ? 39.21092 24.93617  -28.19641 1.000 28.38726 ? 506  ASP A OD1 1 
ATOM   3701 O  OD2 . ASP A  1 475 ? 39.03406 24.12970  -30.23090 1.000 29.74411 ? 506  ASP A OD2 1 
ATOM   3702 N  N   . SER A  1 476 ? 35.60641 28.00754  -28.27013 1.000 21.54036 ? 507  SER A N   1 
ATOM   3703 C  CA  . SER A  1 476 ? 34.61202 28.99996  -28.65826 1.000 23.97608 ? 507  SER A CA  1 
ATOM   3704 C  C   . SER A  1 476 ? 34.61541 29.18312  -30.17384 1.000 23.38113 ? 507  SER A C   1 
ATOM   3705 O  O   . SER A  1 476 ? 35.68179 29.25083  -30.78814 1.000 25.33728 ? 507  SER A O   1 
ATOM   3706 C  CB  . SER A  1 476 ? 34.90054 30.34504  -27.99826 1.000 24.17460 ? 507  SER A CB  1 
ATOM   3707 O  OG  . SER A  1 476 ? 34.00677 31.33157  -28.49007 1.000 23.65099 ? 507  SER A OG  1 
ATOM   3708 N  N   . PRO A  1 477 ? 33.44327 29.28767  -30.80125 1.000 22.08247 ? 508  PRO A N   1 
ATOM   3709 C  CA  . PRO A  1 477 ? 33.41095 29.59103  -32.23875 1.000 27.23205 ? 508  PRO A CA  1 
ATOM   3710 C  C   . PRO A  1 477 ? 33.74226 31.03502  -32.55871 1.000 29.55378 ? 508  PRO A C   1 
ATOM   3711 O  O   . PRO A  1 477 ? 33.84556 31.37862  -33.74030 1.000 30.30789 ? 508  PRO A O   1 
ATOM   3712 C  CB  . PRO A  1 477 ? 31.97004 29.25576  -32.63848 1.000 28.51519 ? 508  PRO A CB  1 
ATOM   3713 C  CG  . PRO A  1 477 ? 31.18358 29.39464  -31.37685 1.000 28.09271 ? 508  PRO A CG  1 
ATOM   3714 C  CD  . PRO A  1 477 ? 32.09858 29.08081  -30.23399 1.000 23.84381 ? 508  PRO A CD  1 
ATOM   3715 N  N   . TYR A  1 478 ? 33.92175 31.88319  -31.54937 1.000 27.15604 ? 509  TYR A N   1 
ATOM   3716 C  CA  . TYR A  1 478 ? 34.16870 33.30162  -31.75128 1.000 27.37438 ? 509  TYR A CA  1 
ATOM   3717 C  C   . TYR A  1 478 ? 35.60217 33.69314  -31.41963 1.000 36.34696 ? 509  TYR A C   1 
ATOM   3718 O  O   . TYR A  1 478 ? 35.95008 34.87256  -31.52612 1.000 41.11244 ? 509  TYR A O   1 
ATOM   3719 C  CB  . TYR A  1 478 ? 33.17350 34.12140  -30.91388 1.000 25.83240 ? 509  TYR A CB  1 
ATOM   3720 C  CG  . TYR A  1 478 ? 31.76890 33.55514  -30.97391 1.000 27.96842 ? 509  TYR A CG  1 
ATOM   3721 C  CD1 . TYR A  1 478 ? 31.01145 33.64202  -32.13393 1.000 25.92656 ? 509  TYR A CD1 1 
ATOM   3722 C  CD2 . TYR A  1 478 ? 31.20455 32.91272  -29.87466 1.000 25.40670 ? 509  TYR A CD2 1 
ATOM   3723 C  CE1 . TYR A  1 478 ? 29.73176 33.10810  -32.20298 1.000 27.67051 ? 509  TYR A CE1 1 
ATOM   3724 C  CE2 . TYR A  1 478 ? 29.93007 32.38453  -29.93546 1.000 24.73365 ? 509  TYR A CE2 1 
ATOM   3725 C  CZ  . TYR A  1 478 ? 29.19581 32.47689  -31.09831 1.000 25.36603 ? 509  TYR A CZ  1 
ATOM   3726 O  OH  . TYR A  1 478 ? 27.92842 31.94108  -31.17771 1.000 23.94197 ? 509  TYR A OH  1 
ATOM   3727 N  N   . HIS A  1 479 ? 36.43685 32.73767  -31.02569 1.000 35.97961 ? 510  HIS A N   1 
ATOM   3728 C  CA  . HIS A  1 479 ? 37.82870 33.00242  -30.67609 1.000 44.40623 ? 510  HIS A CA  1 
ATOM   3729 C  C   . HIS A  1 479 ? 38.76067 32.14075  -31.52144 1.000 52.08040 ? 510  HIS A C   1 
ATOM   3730 O  O   . HIS A  1 479 ? 38.77705 32.24646  -32.74891 1.000 59.30369 ? 510  HIS A O   1 
ATOM   3731 C  CB  . HIS A  1 479 ? 38.07672 32.73709  -29.18588 1.000 48.23987 ? 510  HIS A CB  1 
ATOM   3732 C  CG  . HIS A  1 479 ? 37.24242 33.58135  -28.26843 1.000 42.60885 ? 510  HIS A CG  1 
ATOM   3733 N  ND1 . HIS A  1 479 ? 37.79140 34.49652  -27.39510 1.000 49.01247 ? 510  HIS A ND1 1 
ATOM   3734 C  CD2 . HIS A  1 479 ? 35.90038 33.64545  -28.08439 1.000 37.03727 ? 510  HIS A CD2 1 
ATOM   3735 C  CE1 . HIS A  1 479 ? 36.82513 35.08883  -26.71499 1.000 37.83725 ? 510  HIS A CE1 1 
ATOM   3736 N  NE2 . HIS A  1 479 ? 35.66793 34.59398  -27.11699 1.000 40.26538 ? 510  HIS A NE2 1 
ATOM   3737 N  N   . GLU B  1 14  ? 8.35358  61.36131  -0.15827  1.000 41.62464 ? 45   GLU B N   1 
ATOM   3738 C  CA  . GLU B  1 14  ? 8.90160  60.11339  -0.69380  1.000 39.73084 ? 45   GLU B CA  1 
ATOM   3739 C  C   . GLU B  1 14  ? 8.67156  58.94871  0.26236   1.000 37.70230 ? 45   GLU B C   1 
ATOM   3740 O  O   . GLU B  1 14  ? 9.21421  58.91992  1.36360   1.000 46.24127 ? 45   GLU B O   1 
ATOM   3741 C  CB  . GLU B  1 14  ? 10.39755 60.25344  -0.98591  1.000 40.78973 ? 45   GLU B CB  1 
ATOM   3742 C  CG  . GLU B  1 14  ? 11.01103 59.00230  -1.60735  1.000 37.01554 ? 45   GLU B CG  1 
ATOM   3743 C  CD  . GLU B  1 14  ? 10.33818 58.61796  -2.91111  1.000 29.74815 ? 45   GLU B CD  1 
ATOM   3744 O  OE1 . GLU B  1 14  ? 10.72096 59.17456  -3.96010  1.000 33.63861 ? 45   GLU B OE1 1 
ATOM   3745 O  OE2 . GLU B  1 14  ? 9.41187  57.77517  -2.88678  1.000 33.94671 ? 45   GLU B OE2 1 
ATOM   3746 N  N   . THR B  1 15  ? 7.86269  57.98288  -0.17258  1.000 33.90316 ? 46   THR B N   1 
ATOM   3747 C  CA  . THR B  1 15  ? 7.51665  56.83420  0.64397   1.000 32.15053 ? 46   THR B CA  1 
ATOM   3748 C  C   . THR B  1 15  ? 8.05021  55.52237  0.09192   1.000 31.65918 ? 46   THR B C   1 
ATOM   3749 O  O   . THR B  1 15  ? 7.96459  54.50359  0.78320   1.000 32.26857 ? 46   THR B O   1 
ATOM   3750 C  CB  . THR B  1 15  ? 5.99420  56.71053  0.77495   1.000 28.47232 ? 46   THR B CB  1 
ATOM   3751 O  OG1 . THR B  1 15  ? 5.43071  56.47444  -0.52299  1.000 33.55537 ? 46   THR B OG1 1 
ATOM   3752 C  CG2 . THR B  1 15  ? 5.39808  57.98698  1.35713   1.000 36.15500 ? 46   THR B CG2 1 
ATOM   3753 N  N   . ARG B  1 16  ? 8.57523  55.51622  -1.12592  1.000 28.06069 ? 47   ARG B N   1 
ATOM   3754 C  CA  . ARG B  1 16  ? 8.91147  54.25856  -1.77541  1.000 26.51141 ? 47   ARG B CA  1 
ATOM   3755 C  C   . ARG B  1 16  ? 10.14229 53.63762  -1.11974  1.000 24.10180 ? 47   ARG B C   1 
ATOM   3756 O  O   . ARG B  1 16  ? 11.05970 54.35770  -0.70984  1.000 23.40483 ? 47   ARG B O   1 
ATOM   3757 C  CB  . ARG B  1 16  ? 9.14935  54.48242  -3.26485  1.000 23.17312 ? 47   ARG B CB  1 
ATOM   3758 C  CG  . ARG B  1 16  ? 7.89602  54.99761  -3.98064  1.000 25.33889 ? 47   ARG B CG  1 
ATOM   3759 C  CD  . ARG B  1 16  ? 8.18446  55.35950  -5.40841  1.000 23.68656 ? 47   ARG B CD  1 
ATOM   3760 N  NE  . ARG B  1 16  ? 9.11586  56.47719  -5.48164  1.000 24.10995 ? 47   ARG B NE  1 
ATOM   3761 C  CZ  . ARG B  1 16  ? 9.75289  56.85394  -6.58077  1.000 24.73257 ? 47   ARG B CZ  1 
ATOM   3762 N  NH1 . ARG B  1 16  ? 9.60257  56.20469  -7.72235  1.000 22.29351 ? 47   ARG B NH1 1 
ATOM   3763 N  NH2 . ARG B  1 16  ? 10.56807 57.90595  -6.52918  1.000 27.01530 ? 47   ARG B NH2 1 
ATOM   3764 N  N   . PRO B  1 17  ? 10.19219 52.31202  -1.00848  1.000 20.36607 ? 48   PRO B N   1 
ATOM   3765 C  CA  . PRO B  1 17  ? 11.29531 51.66566  -0.29571  1.000 21.59540 ? 48   PRO B CA  1 
ATOM   3766 C  C   . PRO B  1 17  ? 12.57715 51.61411  -1.11389  1.000 20.47774 ? 48   PRO B C   1 
ATOM   3767 O  O   . PRO B  1 17  ? 12.56620 51.55800  -2.34495  1.000 20.50156 ? 48   PRO B O   1 
ATOM   3768 C  CB  . PRO B  1 17  ? 10.75695 50.24853  -0.04513  1.000 20.73230 ? 48   PRO B CB  1 
ATOM   3769 C  CG  . PRO B  1 17  ? 9.86323  50.00401  -1.24194  1.000 21.66974 ? 48   PRO B CG  1 
ATOM   3770 C  CD  . PRO B  1 17  ? 9.16725  51.33730  -1.43389  1.000 21.87686 ? 48   PRO B CD  1 
ATOM   3771 N  N   . ASN B  1 18  ? 13.69568 51.65829  -0.40230  1.000 18.37599 ? 49   ASN B N   1 
ATOM   3772 C  CA  . ASN B  1 18  ? 14.94830 51.24827  -1.01354  1.000 19.32867 ? 49   ASN B CA  1 
ATOM   3773 C  C   . ASN B  1 18  ? 14.89135 49.75863  -1.31840  1.000 17.52039 ? 49   ASN B C   1 
ATOM   3774 O  O   . ASN B  1 18  ? 14.15136 49.00227  -0.68778  1.000 18.13850 ? 49   ASN B O   1 
ATOM   3775 C  CB  . ASN B  1 18  ? 16.11947 51.51989  -0.08287  1.000 19.83286 ? 49   ASN B CB  1 
ATOM   3776 C  CG  . ASN B  1 18  ? 16.11219 52.92067  0.44648   1.000 22.64922 ? 49   ASN B CG  1 
ATOM   3777 O  OD1 . ASN B  1 18  ? 16.12887 53.88168  -0.32332  1.000 22.17084 ? 49   ASN B OD1 1 
ATOM   3778 N  ND2 . ASN B  1 18  ? 16.04569 53.05221  1.76496   1.000 21.25181 ? 49   ASN B ND2 1 
ATOM   3779 N  N   . ILE B  1 19  ? 15.69033 49.33911  -2.29696  1.000 17.58967 ? 50   ILE B N   1 
ATOM   3780 C  CA  . ILE B  1 19  ? 15.74710 47.94490  -2.71546  1.000 16.90045 ? 50   ILE B CA  1 
ATOM   3781 C  C   . ILE B  1 19  ? 17.20521 47.54658  -2.83724  1.000 17.35966 ? 50   ILE B C   1 
ATOM   3782 O  O   . ILE B  1 19  ? 17.95582 48.14524  -3.61864  1.000 18.25881 ? 50   ILE B O   1 
ATOM   3783 C  CB  . ILE B  1 19  ? 15.01899 47.70802  -4.04729  1.000 17.78421 ? 50   ILE B CB  1 
ATOM   3784 C  CG1 . ILE B  1 19  ? 13.54469 48.09656  -3.92571  1.000 19.40384 ? 50   ILE B CG1 1 
ATOM   3785 C  CG2 . ILE B  1 19  ? 15.17138 46.23543  -4.46794  1.000 19.98625 ? 50   ILE B CG2 1 
ATOM   3786 C  CD1 . ILE B  1 19  ? 12.82159 48.15075  -5.25916  1.000 21.27188 ? 50   ILE B CD1 1 
ATOM   3787 N  N   . LEU B  1 20  ? 17.60496 46.54456  -2.06737  1.000 16.91482 ? 51   LEU B N   1 
ATOM   3788 C  CA  . LEU B  1 20  ? 18.95733 46.00545  -2.11257  1.000 16.29960 ? 51   LEU B CA  1 
ATOM   3789 C  C   . LEU B  1 20  ? 18.84864 44.54492  -2.50805  1.000 17.01538 ? 51   LEU B C   1 
ATOM   3790 O  O   . LEU B  1 20  ? 18.22359 43.75659  -1.79419  1.000 17.50557 ? 51   LEU B O   1 
ATOM   3791 C  CB  . LEU B  1 20  ? 19.65590 46.15529  -0.75722  1.000 16.61135 ? 51   LEU B CB  1 
ATOM   3792 C  CG  . LEU B  1 20  ? 20.96184 45.36667  -0.57902  1.000 19.96084 ? 51   LEU B CG  1 
ATOM   3793 C  CD1 . LEU B  1 20  ? 22.03241 45.86600  -1.55232  1.000 20.30622 ? 51   LEU B CD1 1 
ATOM   3794 C  CD2 . LEU B  1 20  ? 21.46173 45.46231  0.86116   1.000 20.51743 ? 51   LEU B CD2 1 
ATOM   3795 N  N   . VAL B  1 21  ? 19.43410 44.19189  -3.64484  1.000 17.51178 ? 52   VAL B N   1 
ATOM   3796 C  CA  . VAL B  1 21  ? 19.54389 42.80353  -4.07412  1.000 16.27107 ? 52   VAL B CA  1 
ATOM   3797 C  C   . VAL B  1 21  ? 20.94136 42.33712  -3.71469  1.000 18.64774 ? 52   VAL B C   1 
ATOM   3798 O  O   . VAL B  1 21  ? 21.92829 42.90370  -4.19704  1.000 18.20109 ? 52   VAL B O   1 
ATOM   3799 C  CB  . VAL B  1 21  ? 19.29936 42.64142  -5.57973  1.000 16.85534 ? 52   VAL B CB  1 
ATOM   3800 C  CG1 . VAL B  1 21  ? 19.56650 41.18752  -6.00483  1.000 19.16729 ? 52   VAL B CG1 1 
ATOM   3801 C  CG2 . VAL B  1 21  ? 17.87789 43.05059  -5.94690  1.000 17.89298 ? 52   VAL B CG2 1 
ATOM   3802 N  N   . VAL B  1 22  ? 21.03162 41.33781  -2.85043  1.000 17.68731 ? 53   VAL B N   1 
ATOM   3803 C  CA  . VAL B  1 22  ? 22.29999 40.68831  -2.54465  1.000 16.42269 ? 53   VAL B CA  1 
ATOM   3804 C  C   . VAL B  1 22  ? 22.28157 39.36239  -3.28831  1.000 16.40840 ? 53   VAL B C   1 
ATOM   3805 O  O   . VAL B  1 22  ? 21.56299 38.43505  -2.90266  1.000 15.93811 ? 53   VAL B O   1 
ATOM   3806 C  CB  . VAL B  1 22  ? 22.50242 40.48292  -1.03887  1.000 16.46449 ? 53   VAL B CB  1 
ATOM   3807 C  CG1 . VAL B  1 22  ? 23.88269 39.86935  -0.76962  1.000 17.35402 ? 53   VAL B CG1 1 
ATOM   3808 C  CG2 . VAL B  1 22  ? 22.34137 41.80246  -0.27336  1.000 18.64082 ? 53   VAL B CG2 1 
ATOM   3809 N  N   . LEU B  1 23  ? 23.06310 39.27085  -4.35956  1.000 17.47206 ? 54   LEU B N   1 
ATOM   3810 C  CA  . LEU B  1 23  ? 23.05987 38.11310  -5.24495  1.000 16.71906 ? 54   LEU B CA  1 
ATOM   3811 C  C   . LEU B  1 23  ? 24.41600 37.43594  -5.13912  1.000 15.99457 ? 54   LEU B C   1 
ATOM   3812 O  O   . LEU B  1 23  ? 25.43150 38.02688  -5.51162  1.000 17.87527 ? 54   LEU B O   1 
ATOM   3813 C  CB  . LEU B  1 23  ? 22.78432 38.55688  -6.67910  1.000 18.12892 ? 54   LEU B CB  1 
ATOM   3814 C  CG  . LEU B  1 23  ? 22.80564 37.46056  -7.73318  1.000 16.63381 ? 54   LEU B CG  1 
ATOM   3815 C  CD1 . LEU B  1 23  ? 21.64922 36.48440  -7.50326  1.000 16.54461 ? 54   LEU B CD1 1 
ATOM   3816 C  CD2 . LEU B  1 23  ? 22.73757 38.10547  -9.12860  1.000 17.96682 ? 54   LEU B CD2 1 
ATOM   3817 N  N   . CYS B  1 24  ? 24.43425 36.22172  -4.60295  1.000 14.48335 ? 55   CYS B N   1 
ATOM   3818 C  CA  . CYS B  1 24  ? 25.64458 35.41469  -4.58769  1.000 16.66022 ? 55   CYS B CA  1 
ATOM   3819 C  C   . CYS B  1 24  ? 25.73445 34.58301  -5.86031  1.000 18.31799 ? 55   CYS B C   1 
ATOM   3820 O  O   . CYS B  1 24  ? 24.76825 34.42975  -6.60473  1.000 18.04815 ? 55   CYS B O   1 
ATOM   3821 C  CB  . CYS B  1 24  ? 25.67981 34.51772  -3.35341  1.000 18.06599 ? 55   CYS B CB  1 
ATOM   3822 S  SG  . CYS B  1 24  ? 26.12059 35.43131  -1.86153  1.000 21.09618 ? 55   CYS B SG  1 
ATOM   3823 N  N   . ASP B  1 25  ? 26.92297 34.03701  -6.09969  1.000 16.54318 ? 56   ASP B N   1 
ATOM   3824 C  CA  . ASP B  1 25  ? 27.27677 33.37477  -7.35124  1.000 16.86923 ? 56   ASP B CA  1 
ATOM   3825 C  C   . ASP B  1 25  ? 27.62856 31.92391  -7.03889  1.000 16.46259 ? 56   ASP B C   1 
ATOM   3826 O  O   . ASP B  1 25  ? 28.64935 31.66378  -6.39751  1.000 17.05250 ? 56   ASP B O   1 
ATOM   3827 C  CB  . ASP B  1 25  ? 28.45784 34.10848  -7.99836  1.000 17.00787 ? 56   ASP B CB  1 
ATOM   3828 C  CG  . ASP B  1 25  ? 28.74119 33.65771  -9.41193  1.000 19.31700 ? 56   ASP B CG  1 
ATOM   3829 O  OD1 . ASP B  1 25  ? 28.08275 32.71379  -9.88903  1.000 19.70865 ? 56   ASP B OD1 1 
ATOM   3830 O  OD2 . ASP B  1 25  ? 29.63291 34.27753  -10.05025 1.000 18.62502 ? 56   ASP B OD2 1 
ATOM   3831 N  N   . ASP B  1 26  ? 26.78187 30.97716  -7.47335  1.000 17.14717 ? 57   ASP B N   1 
ATOM   3832 C  CA  . ASP B  1 26  ? 26.99714 29.53867  -7.23129  1.000 15.48194 ? 57   ASP B CA  1 
ATOM   3833 C  C   . ASP B  1 26  ? 26.91583 29.17358  -5.74648  1.000 15.11811 ? 57   ASP B C   1 
ATOM   3834 O  O   . ASP B  1 26  ? 27.64497 28.28795  -5.28942  1.000 15.98988 ? 57   ASP B O   1 
ATOM   3835 C  CB  . ASP B  1 26  ? 28.35659 29.03148  -7.76273  1.000 16.77375 ? 57   ASP B CB  1 
ATOM   3836 C  CG  . ASP B  1 26  ? 28.50223 29.10483  -9.27631  1.000 18.97316 ? 57   ASP B CG  1 
ATOM   3837 O  OD1 . ASP B  1 26  ? 27.55275 29.51249  -9.96434  1.000 17.73179 ? 57   ASP B OD1 1 
ATOM   3838 O  OD2 . ASP B  1 26  ? 29.60384 28.73403  -9.77120  1.000 18.46166 ? 57   ASP B OD2 1 
ATOM   3839 N  N   . LEU B  1 27  ? 26.06061 29.84670  -4.97374  1.000 16.73838 ? 58   LEU B N   1 
ATOM   3840 C  CA  . LEU B  1 27  ? 25.86103 29.48942  -3.57098  1.000 15.60490 ? 58   LEU B CA  1 
ATOM   3841 C  C   . LEU B  1 27  ? 24.95106 28.26867  -3.45124  1.000 17.36581 ? 58   LEU B C   1 
ATOM   3842 O  O   . LEU B  1 27  ? 23.83115 28.26041  -3.97679  1.000 17.86426 ? 58   LEU B O   1 
ATOM   3843 C  CB  . LEU B  1 27  ? 25.26380 30.67504  -2.81077  1.000 15.66697 ? 58   LEU B CB  1 
ATOM   3844 C  CG  . LEU B  1 27  ? 24.90895 30.43266  -1.34450  1.000 16.67989 ? 58   LEU B CG  1 
ATOM   3845 C  CD1 . LEU B  1 27  ? 26.17835 30.24581  -0.52961  1.000 18.63991 ? 58   LEU B CD1 1 
ATOM   3846 C  CD2 . LEU B  1 27  ? 24.08826 31.62012  -0.82767  1.000 18.64702 ? 58   LEU B CD2 1 
ATOM   3847 N  N   . GLY B  1 28  ? 25.43570 27.23582  -2.75518  1.000 16.16376 ? 59   GLY B N   1 
ATOM   3848 C  CA  . GLY B  1 28  ? 24.67897 26.00596  -2.62962  1.000 15.86244 ? 59   GLY B CA  1 
ATOM   3849 C  C   . GLY B  1 28  ? 23.49372 26.11349  -1.68537  1.000 15.54153 ? 59   GLY B C   1 
ATOM   3850 O  O   . GLY B  1 28  ? 23.43405 26.96035  -0.79745  1.000 16.69495 ? 59   GLY B O   1 
ATOM   3851 N  N   . TYR B  1 29  ? 22.54380 25.19529  -1.89029  1.000 14.97475 ? 60   TYR B N   1 
ATOM   3852 C  CA  . TYR B  1 29  ? 21.25895 25.26356  -1.19331  1.000 14.74951 ? 60   TYR B CA  1 
ATOM   3853 C  C   . TYR B  1 29  ? 21.41495 25.11388  0.30903   1.000 18.51055 ? 60   TYR B C   1 
ATOM   3854 O  O   . TYR B  1 29  ? 20.64990 25.71336  1.07088   1.000 19.31461 ? 60   TYR B O   1 
ATOM   3855 C  CB  . TYR B  1 29  ? 20.31793 24.18312  -1.72248  1.000 15.70074 ? 60   TYR B CB  1 
ATOM   3856 C  CG  . TYR B  1 29  ? 18.84731 24.51647  -1.56030  1.000 13.80336 ? 60   TYR B CG  1 
ATOM   3857 C  CD1 . TYR B  1 29  ? 18.30149 25.63302  -2.17268  1.000 16.54229 ? 60   TYR B CD1 1 
ATOM   3858 C  CD2 . TYR B  1 29  ? 18.00512 23.68994  -0.81859  1.000 14.23251 ? 60   TYR B CD2 1 
ATOM   3859 C  CE1 . TYR B  1 29  ? 16.94572 25.93501  -2.03674  1.000 16.24467 ? 60   TYR B CE1 1 
ATOM   3860 C  CE2 . TYR B  1 29  ? 16.64619 23.97540  -0.68828  1.000 14.82937 ? 60   TYR B CE2 1 
ATOM   3861 C  CZ  . TYR B  1 29  ? 16.12786 25.09455  -1.30111  1.000 16.31532 ? 60   TYR B CZ  1 
ATOM   3862 O  OH  . TYR B  1 29  ? 14.78431 25.37944  -1.16435  1.000 17.68212 ? 60   TYR B OH  1 
ATOM   3863 N  N   . ALA B  1 30  ? 22.38713 24.32211  0.75802   1.000 16.75076 ? 61   ALA B N   1 
ATOM   3864 C  CA  . ALA B  1 30  ? 22.55588 24.05070  2.18032   1.000 16.96638 ? 61   ALA B CA  1 
ATOM   3865 C  C   . ALA B  1 30  ? 23.74403 24.80764  2.75818   1.000 19.98240 ? 61   ALA B C   1 
ATOM   3866 O  O   . ALA B  1 30  ? 24.36814 24.34730  3.71413   1.000 20.34262 ? 61   ALA B O   1 
ATOM   3867 C  CB  . ALA B  1 30  ? 22.71819 22.55289  2.42478   1.000 19.26236 ? 61   ALA B CB  1 
ATOM   3868 N  N   . ASP B  1 31  ? 24.07453 25.96161  2.18640   1.000 17.19609 ? 62   ASP B N   1 
ATOM   3869 C  CA  . ASP B  1 31  ? 25.32303 26.63913  2.51536   1.000 15.91816 ? 62   ASP B CA  1 
ATOM   3870 C  C   . ASP B  1 31  ? 25.10972 27.98783  3.19306   1.000 17.34001 ? 62   ASP B C   1 
ATOM   3871 O  O   . ASP B  1 31  ? 26.05900 28.77862  3.31517   1.000 17.13713 ? 62   ASP B O   1 
ATOM   3872 C  CB  . ASP B  1 31  ? 26.16708 26.76330  1.24607   1.000 17.50337 ? 62   ASP B CB  1 
ATOM   3873 C  CG  . ASP B  1 31  ? 26.62001 25.39316  0.72857   1.000 17.22906 ? 62   ASP B CG  1 
ATOM   3874 O  OD1 . ASP B  1 31  ? 26.64046 24.43050  1.52858   1.000 19.67565 ? 62   ASP B OD1 1 
ATOM   3875 O  OD2 . ASP B  1 31  ? 26.94573 25.26238  -0.47141  1.000 18.32750 ? 62   ASP B OD2 1 
ATOM   3876 N  N   . VAL B  1 32  ? 23.89036 28.26756  3.64078   1.000 17.30027 ? 63   VAL B N   1 
ATOM   3877 C  CA  . VAL B  1 32  ? 23.61672 29.36015  4.56434   1.000 16.70438 ? 63   VAL B CA  1 
ATOM   3878 C  C   . VAL B  1 32  ? 22.81725 28.78133  5.72010   1.000 15.88789 ? 63   VAL B C   1 
ATOM   3879 O  O   . VAL B  1 32  ? 22.04755 27.83394  5.54739   1.000 17.46333 ? 63   VAL B O   1 
ATOM   3880 C  CB  . VAL B  1 32  ? 22.86068 30.53285  3.90136   1.000 16.93998 ? 63   VAL B CB  1 
ATOM   3881 C  CG1 . VAL B  1 32  ? 23.79059 31.27835  2.95121   1.000 19.58640 ? 63   VAL B CG1 1 
ATOM   3882 C  CG2 . VAL B  1 32  ? 21.61177 30.01789  3.17003   1.000 20.29807 ? 63   VAL B CG2 1 
ATOM   3883 N  N   . GLY B  1 33  ? 23.02093 29.34172  6.91263   1.000 17.10880 ? 64   GLY B N   1 
ATOM   3884 C  CA  . GLY B  1 33  ? 22.37727 28.78067  8.09539   1.000 19.94217 ? 64   GLY B CA  1 
ATOM   3885 C  C   . GLY B  1 33  ? 20.86421 28.72092  7.97881   1.000 19.87331 ? 64   GLY B C   1 
ATOM   3886 O  O   . GLY B  1 33  ? 20.23840 27.72650  8.36421   1.000 20.71729 ? 64   GLY B O   1 
ATOM   3887 N  N   . PHE B  1 34  ? 20.25540 29.77347  7.43629   1.000 17.77589 ? 65   PHE B N   1 
ATOM   3888 C  CA  . PHE B  1 34  ? 18.79785 29.84638  7.44951   1.000 18.83029 ? 65   PHE B CA  1 
ATOM   3889 C  C   . PHE B  1 34  ? 18.16608 28.85754  6.48848   1.000 19.94053 ? 65   PHE B C   1 
ATOM   3890 O  O   . PHE B  1 34  ? 16.95768 28.60362  6.58063   1.000 20.36434 ? 65   PHE B O   1 
ATOM   3891 C  CB  . PHE B  1 34  ? 18.31903 31.26716  7.13775   1.000 16.76453 ? 65   PHE B CB  1 
ATOM   3892 C  CG  . PHE B  1 34  ? 18.53408 31.70397  5.71098   1.000 16.25050 ? 65   PHE B CG  1 
ATOM   3893 C  CD1 . PHE B  1 34  ? 17.60140 31.38619  4.72171   1.000 17.07691 ? 65   PHE B CD1 1 
ATOM   3894 C  CD2 . PHE B  1 34  ? 19.64164 32.46119  5.36960   1.000 17.79979 ? 65   PHE B CD2 1 
ATOM   3895 C  CE1 . PHE B  1 34  ? 17.78371 31.80256  3.41376   1.000 17.56833 ? 65   PHE B CE1 1 
ATOM   3896 C  CE2 . PHE B  1 34  ? 19.82436 32.89456  4.06769   1.000 18.66318 ? 65   PHE B CE2 1 
ATOM   3897 C  CZ  . PHE B  1 34  ? 18.89780 32.55775  3.08683   1.000 17.80108 ? 65   PHE B CZ  1 
ATOM   3898 N  N   . ASN B  1 35  ? 18.94895 28.30128  5.56792   1.000 18.06032 ? 66   ASN B N   1 
ATOM   3899 C  CA  . ASN B  1 35  ? 18.45406 27.29532  4.64073   1.000 17.61046 ? 66   ASN B CA  1 
ATOM   3900 C  C   . ASN B  1 35  ? 18.98488 25.89757  4.95145   1.000 19.35841 ? 66   ASN B C   1 
ATOM   3901 O  O   . ASN B  1 35  ? 18.92188 25.00855  4.09342   1.000 22.76207 ? 66   ASN B O   1 
ATOM   3902 C  CB  . ASN B  1 35  ? 18.79737 27.68744  3.20615   1.000 19.06221 ? 66   ASN B CB  1 
ATOM   3903 C  CG  . ASN B  1 35  ? 17.68974 27.33426  2.24851   1.000 19.54031 ? 66   ASN B CG  1 
ATOM   3904 O  OD1 . ASN B  1 35  ? 16.51169 27.56204  2.53953   1.000 21.36823 ? 66   ASN B OD1 1 
ATOM   3905 N  ND2 . ASN B  1 35  ? 18.04350 26.73243  1.12896   1.000 17.96326 ? 66   ASN B ND2 1 
ATOM   3906 N  N   . GLY B  1 36  ? 19.51941 25.68870  6.15418   1.000 17.82690 ? 67   GLY B N   1 
ATOM   3907 C  CA  . GLY B  1 36  ? 19.82926 24.35975  6.64783   1.000 20.59583 ? 67   GLY B CA  1 
ATOM   3908 C  C   . GLY B  1 36  ? 21.29656 24.07553  6.88020   1.000 23.17415 ? 67   GLY B C   1 
ATOM   3909 O  O   . GLY B  1 36  ? 21.62259 22.95801  7.30574   1.000 23.11110 ? 67   GLY B O   1 
ATOM   3910 N  N   . SER B  1 37  ? 22.21453 25.00415  6.62234   1.000 19.89442 ? 68   SER B N   1 
ATOM   3911 C  CA  . SER B  1 37  ? 23.62273 24.68379  6.80699   1.000 19.68617 ? 68   SER B CA  1 
ATOM   3912 C  C   . SER B  1 37  ? 23.91453 24.35069  8.26273   1.000 21.58448 ? 68   SER B C   1 
ATOM   3913 O  O   . SER B  1 37  ? 23.49954 25.07099  9.17859   1.000 24.47309 ? 68   SER B O   1 
ATOM   3914 C  CB  . SER B  1 37  ? 24.51313 25.83472  6.36171   1.000 20.18129 ? 68   SER B CB  1 
ATOM   3915 O  OG  . SER B  1 37  ? 25.84325 25.35454  6.23879   1.000 22.84550 ? 68   SER B OG  1 
ATOM   3916 N  N   . THR B  1 38  ? 24.65487 23.26414  8.46594   1.000 22.98986 ? 69   THR B N   1 
ATOM   3917 C  CA  . THR B  1 38  ? 25.11494 22.88793  9.79295   1.000 25.73263 ? 69   THR B CA  1 
ATOM   3918 C  C   . THR B  1 38  ? 26.57303 23.25327  10.03328  1.000 29.46690 ? 69   THR B C   1 
ATOM   3919 O  O   . THR B  1 38  ? 27.01721 23.23471  11.18697  1.000 28.29110 ? 69   THR B O   1 
ATOM   3920 C  CB  . THR B  1 38  ? 24.91251 21.38042  10.01654  1.000 27.96087 ? 69   THR B CB  1 
ATOM   3921 O  OG1 . THR B  1 38  ? 25.65935 20.63131  9.04750   1.000 29.28478 ? 69   THR B OG1 1 
ATOM   3922 C  CG2 . THR B  1 38  ? 23.44292 21.02868  9.87808   1.000 33.90318 ? 69   THR B CG2 1 
ATOM   3923 N  N   . ASP B  1 39  ? 27.32127 23.61080  8.98608   1.000 20.47773 ? 70   ASP B N   1 
ATOM   3924 C  CA  . ASP B  1 39  ? 28.73700 23.89408  9.14692   1.000 19.73863 ? 70   ASP B CA  1 
ATOM   3925 C  C   . ASP B  1 39  ? 29.16908 25.26784  8.66372   1.000 21.02798 ? 70   ASP B C   1 
ATOM   3926 O  O   . ASP B  1 39  ? 30.16254 25.79152  9.17652   1.000 22.49621 ? 70   ASP B O   1 
ATOM   3927 C  CB  . ASP B  1 39  ? 29.59908 22.81533  8.45360   1.000 20.77794 ? 70   ASP B CB  1 
ATOM   3928 C  CG  . ASP B  1 39  ? 29.28285 22.64218  6.97722   1.000 26.26408 ? 70   ASP B CG  1 
ATOM   3929 O  OD1 . ASP B  1 39  ? 28.26426 23.18097  6.48856   1.000 21.88652 ? 70   ASP B OD1 1 
ATOM   3930 O  OD2 . ASP B  1 39  ? 30.07543 21.94957  6.29590   1.000 25.62066 ? 70   ASP B OD2 1 
ATOM   3931 N  N   . ILE B  1 40  ? 28.45614 25.88902  7.73469   1.000 18.72285 ? 71   ILE B N   1 
ATOM   3932 C  CA  . ILE B  1 40  ? 28.81036 27.23942  7.31659   1.000 20.24089 ? 71   ILE B CA  1 
ATOM   3933 C  C   . ILE B  1 40  ? 28.03986 28.21502  8.18987   1.000 21.36357 ? 71   ILE B C   1 
ATOM   3934 O  O   . ILE B  1 40  ? 26.82990 28.06043  8.39082   1.000 22.59953 ? 71   ILE B O   1 
ATOM   3935 C  CB  . ILE B  1 40  ? 28.52326 27.45389  5.82136   1.000 19.57040 ? 71   ILE B CB  1 
ATOM   3936 C  CG1 . ILE B  1 40  ? 29.36076 26.46525  5.00930   1.000 22.37287 ? 71   ILE B CG1 1 
ATOM   3937 C  CG2 . ILE B  1 40  ? 28.87210 28.88843  5.39716   1.000 20.32596 ? 71   ILE B CG2 1 
ATOM   3938 C  CD1 . ILE B  1 40  ? 29.15775 26.54627  3.49946   1.000 22.05200 ? 71   ILE B CD1 1 
ATOM   3939 N  N   . LEU B  1 41  ? 28.74681 29.19126  8.74386   1.000 19.27407 ? 72   LEU B N   1 
ATOM   3940 C  CA  . LEU B  1 41  ? 28.18237 30.12722  9.70439   1.000 22.22068 ? 72   LEU B CA  1 
ATOM   3941 C  C   . LEU B  1 41  ? 27.85817 31.42581  8.98497   1.000 21.00430 ? 72   LEU B C   1 
ATOM   3942 O  O   . LEU B  1 41  ? 28.74652 32.05058  8.39501   1.000 20.46178 ? 72   LEU B O   1 
ATOM   3943 C  CB  . LEU B  1 41  ? 29.16266 30.37667  10.84799  1.000 24.12328 ? 72   LEU B CB  1 
ATOM   3944 C  CG  . LEU B  1 41  ? 29.53470 29.13273  11.65205  1.000 27.39949 ? 72   LEU B CG  1 
ATOM   3945 C  CD1 . LEU B  1 41  ? 30.70664 29.46411  12.56462  1.000 31.53982 ? 72   LEU B CD1 1 
ATOM   3946 C  CD2 . LEU B  1 41  ? 28.33591 28.65270  12.44434  1.000 30.51699 ? 72   LEU B CD2 1 
ATOM   3947 N  N   . THR B  1 42  ? 26.58742 31.82871  9.02309   1.000 20.26448 ? 73   THR B N   1 
ATOM   3948 C  CA  . THR B  1 42  ? 26.13442 33.05750  8.36917   1.000 18.66577 ? 73   THR B CA  1 
ATOM   3949 C  C   . THR B  1 42  ? 25.21965 33.81912  9.32066   1.000 18.97136 ? 73   THR B C   1 
ATOM   3950 O  O   . THR B  1 42  ? 24.02670 33.99621  9.05626   1.000 18.60426 ? 73   THR B O   1 
ATOM   3951 C  CB  . THR B  1 42  ? 25.41752 32.74476  7.04897   1.000 19.05478 ? 73   THR B CB  1 
ATOM   3952 O  OG1 . THR B  1 42  ? 24.29720 31.88593  7.28795   1.000 19.46108 ? 73   THR B OG1 1 
ATOM   3953 C  CG2 . THR B  1 42  ? 26.36095 32.07192  6.05380   1.000 20.02107 ? 73   THR B CG2 1 
ATOM   3954 N  N   . PRO B  1 43  ? 25.75936 34.30918  10.44141  1.000 17.65400 ? 74   PRO B N   1 
ATOM   3955 C  CA  . PRO B  1 43  ? 24.87735 34.90908  11.45956  1.000 21.01344 ? 74   PRO B CA  1 
ATOM   3956 C  C   . PRO B  1 43  ? 24.14204 36.15060  10.98916  1.000 19.03885 ? 74   PRO B C   1 
ATOM   3957 O  O   . PRO B  1 43  ? 22.98409 36.35655  11.37853  1.000 19.91819 ? 74   PRO B O   1 
ATOM   3958 C  CB  . PRO B  1 43  ? 25.84157 35.22627  12.61031  1.000 20.74999 ? 74   PRO B CB  1 
ATOM   3959 C  CG  . PRO B  1 43  ? 27.19808 35.29838  11.96432  1.000 19.28957 ? 74   PRO B CG  1 
ATOM   3960 C  CD  . PRO B  1 43  ? 27.16783 34.26631  10.88275  1.000 21.46751 ? 74   PRO B CD  1 
ATOM   3961 N  N   . GLU B  1 44  ? 24.77865 37.00265  10.17700  1.000 17.70006 ? 75   GLU B N   1 
ATOM   3962 C  CA  . GLU B  1 44  ? 24.10483 38.22837  9.75158   1.000 18.30973 ? 75   GLU B CA  1 
ATOM   3963 C  C   . GLU B  1 44  ? 22.98778 37.92616  8.76175   1.000 20.38238 ? 75   GLU B C   1 
ATOM   3964 O  O   . GLU B  1 44  ? 21.88412 38.47872  8.87518   1.000 19.08303 ? 75   GLU B O   1 
ATOM   3965 C  CB  . GLU B  1 44  ? 25.11842 39.20390  9.15079   1.000 18.89743 ? 75   GLU B CB  1 
ATOM   3966 C  CG  . GLU B  1 44  ? 26.25372 39.55452  10.10709  1.000 21.75791 ? 75   GLU B CG  1 
ATOM   3967 C  CD  . GLU B  1 44  ? 25.80869 40.46352  11.23851  1.000 28.19248 ? 75   GLU B CD  1 
ATOM   3968 O  OE1 . GLU B  1 44  ? 24.68254 41.00625  11.19014  1.000 26.92021 ? 75   GLU B OE1 1 
ATOM   3969 O  OE2 . GLU B  1 44  ? 26.59769 40.64454  12.17923  1.000 31.25013 ? 75   GLU B OE2 1 
ATOM   3970 N  N   . LEU B  1 45  ? 23.24965 37.04703  7.78643   1.000 18.06624 ? 76   LEU B N   1 
ATOM   3971 C  CA  . LEU B  1 45  ? 22.19516 36.65007  6.85905   1.000 16.60443 ? 76   LEU B CA  1 
ATOM   3972 C  C   . LEU B  1 45  ? 21.06893 35.93184  7.58832   1.000 18.76729 ? 76   LEU B C   1 
ATOM   3973 O  O   . LEU B  1 45  ? 19.88638 36.15212  7.29214   1.000 19.12889 ? 76   LEU B O   1 
ATOM   3974 C  CB  . LEU B  1 45  ? 22.76616 35.75796  5.75110   1.000 17.76950 ? 76   LEU B CB  1 
ATOM   3975 C  CG  . LEU B  1 45  ? 23.64673 36.46795  4.72286   1.000 19.49333 ? 76   LEU B CG  1 
ATOM   3976 C  CD1 . LEU B  1 45  ? 24.46462 35.46876  3.92531   1.000 19.91605 ? 76   LEU B CD1 1 
ATOM   3977 C  CD2 . LEU B  1 45  ? 22.79761 37.32554  3.78407   1.000 18.93732 ? 76   LEU B CD2 1 
ATOM   3978 N  N   . ASP B  1 46  ? 21.41930 35.05594  8.53866   1.000 17.66397 ? 77   ASP B N   1 
ATOM   3979 C  CA  . ASP B  1 46  ? 20.39976 34.35613  9.31222   1.000 18.62153 ? 77   ASP B CA  1 
ATOM   3980 C  C   . ASP B  1 46  ? 19.52307 35.33415  10.07564  1.000 18.39420 ? 77   ASP B C   1 
ATOM   3981 O  O   . ASP B  1 46  ? 18.30276 35.16085  10.13704  1.000 18.73510 ? 77   ASP B O   1 
ATOM   3982 C  CB  . ASP B  1 46  ? 21.05345 33.38704  10.29222  1.000 18.39844 ? 77   ASP B CB  1 
ATOM   3983 C  CG  . ASP B  1 46  ? 21.70460 32.20643  9.60467   1.000 21.22718 ? 77   ASP B CG  1 
ATOM   3984 O  OD1 . ASP B  1 46  ? 21.65814 32.11198  8.35600   1.000 20.91534 ? 77   ASP B OD1 1 
ATOM   3985 O  OD2 . ASP B  1 46  ? 22.26037 31.36286  10.33800  1.000 21.47255 ? 77   ASP B OD2 1 
ATOM   3986 N  N   . ASN B  1 47  ? 20.12617 36.36844  10.66650  1.000 18.85259 ? 78   ASN B N   1 
ATOM   3987 C  CA  . ASN B  1 47  ? 19.32225 37.30975  11.43236  1.000 20.82150 ? 78   ASN B CA  1 
ATOM   3988 C  C   . ASN B  1 47  ? 18.35428 38.06216  10.52586  1.000 20.90280 ? 78   ASN B C   1 
ATOM   3989 O  O   . ASN B  1 47  ? 17.19837 38.29032  10.90128  1.000 20.60604 ? 78   ASN B O   1 
ATOM   3990 C  CB  . ASN B  1 47  ? 20.21200 38.27915  12.20439  1.000 21.27731 ? 78   ASN B CB  1 
ATOM   3991 C  CG  . ASN B  1 47  ? 19.42847 39.05681  13.24710  1.000 27.83272 ? 78   ASN B CG  1 
ATOM   3992 O  OD1 . ASN B  1 47  ? 18.96326 38.48994  14.23584  1.000 36.05007 ? 78   ASN B OD1 1 
ATOM   3993 N  ND2 . ASN B  1 47  ? 19.25314 40.33973  13.01292  1.000 32.33669 ? 78   ASN B ND2 1 
ATOM   3994 N  N   . LEU B  1 48  ? 18.78886 38.42259  9.31410   1.000 18.04218 ? 79   LEU B N   1 
ATOM   3995 C  CA  . LEU B  1 48  ? 17.86561 39.05011  8.37059   1.000 16.86108 ? 79   LEU B CA  1 
ATOM   3996 C  C   . LEU B  1 48  ? 16.74957 38.09193  7.97029   1.000 18.94065 ? 79   LEU B C   1 
ATOM   3997 O  O   . LEU B  1 48  ? 15.56561 38.45883  7.97528   1.000 18.88225 ? 79   LEU B O   1 
ATOM   3998 C  CB  . LEU B  1 48  ? 18.61574 39.53604  7.12793   1.000 17.14712 ? 79   LEU B CB  1 
ATOM   3999 C  CG  . LEU B  1 48  ? 19.54455 40.72857  7.34439   1.000 18.81824 ? 79   LEU B CG  1 
ATOM   4000 C  CD1 . LEU B  1 48  ? 20.31417 41.01742  6.05805   1.000 19.80843 ? 79   LEU B CD1 1 
ATOM   4001 C  CD2 . LEU B  1 48  ? 18.78813 41.96269  7.81758   1.000 19.26434 ? 79   LEU B CD2 1 
ATOM   4002 N  N   . ALA B  1 49  ? 17.11463 36.86691  7.58276   1.000 16.38792 ? 80   ALA B N   1 
ATOM   4003 C  CA  . ALA B  1 49  ? 16.11723 35.87104  7.19607   1.000 15.19041 ? 80   ALA B CA  1 
ATOM   4004 C  C   . ALA B  1 49  ? 15.10420 35.63784  8.31118   1.000 16.82995 ? 80   ALA B C   1 
ATOM   4005 O  O   . ALA B  1 49  ? 13.89541 35.59598  8.06153   1.000 19.26782 ? 80   ALA B O   1 
ATOM   4006 C  CB  . ALA B  1 49  ? 16.80942 34.55683  6.81611   1.000 17.32205 ? 80   ALA B CB  1 
ATOM   4007 N  N   . GLN B  1 50  ? 15.58180 35.48000  9.55086   1.000 17.77504 ? 81   GLN B N   1 
ATOM   4008 C  CA  . GLN B  1 50  ? 14.67108 35.22503  10.66449  1.000 20.34827 ? 81   GLN B CA  1 
ATOM   4009 C  C   . GLN B  1 50  ? 13.73185 36.39884  10.91068  1.000 20.89351 ? 81   GLN B C   1 
ATOM   4010 O  O   . GLN B  1 50  ? 12.62019 36.20956  11.42665  1.000 21.40253 ? 81   GLN B O   1 
ATOM   4011 C  CB  . GLN B  1 50  ? 15.46840 34.91938  11.93330  1.000 23.21127 ? 81   GLN B CB  1 
ATOM   4012 C  CG  . GLN B  1 50  ? 16.19387 33.57222  11.91484  1.000 26.54244 ? 81   GLN B CG  1 
ATOM   4013 C  CD  . GLN B  1 50  ? 17.35448 33.53877  12.90436  1.000 34.01991 ? 81   GLN B CD  1 
ATOM   4014 O  OE1 . GLN B  1 50  ? 17.52455 34.46160  13.71170  1.000 36.54370 ? 81   GLN B OE1 1 
ATOM   4015 N  NE2 . GLN B  1 50  ? 18.16490 32.48377  12.83796  1.000 32.58960 ? 81   GLN B NE2 1 
ATOM   4016 N  N   . ASN B  1 51  ? 14.15888 37.61215  10.56706  1.000 21.57180 ? 82   ASN B N   1 
ATOM   4017 C  CA  . ASN B  1 51  ? 13.34850 38.80800  10.74752  1.000 18.60103 ? 82   ASN B CA  1 
ATOM   4018 C  C   . ASN B  1 51  ? 12.57827 39.18340  9.49102   1.000 20.20374 ? 82   ASN B C   1 
ATOM   4019 O  O   . ASN B  1 51  ? 12.07014 40.30620  9.39180   1.000 20.15001 ? 82   ASN B O   1 
ATOM   4020 C  CB  . ASN B  1 51  ? 14.23231 39.95806  11.21814  1.000 20.87073 ? 82   ASN B CB  1 
ATOM   4021 C  CG  . ASN B  1 51  ? 14.60575 39.81062  12.67846  1.000 29.31305 ? 82   ASN B CG  1 
ATOM   4022 O  OD1 . ASN B  1 51  ? 13.73000 39.72160  13.53681  1.000 30.75760 ? 82   ASN B OD1 1 
ATOM   4023 N  ND2 . ASN B  1 51  ? 15.90097 39.74005  12.96538  1.000 33.23845 ? 82   ASN B ND2 1 
ATOM   4024 N  N   . GLY B  1 52  ? 12.47654 38.25640  8.54153   1.000 17.92100 ? 83   GLY B N   1 
ATOM   4025 C  CA  . GLY B  1 52  ? 11.69784 38.46217  7.32683   1.000 20.13875 ? 83   GLY B CA  1 
ATOM   4026 C  C   . GLY B  1 52  ? 11.06769 37.16979  6.87253   1.000 18.71708 ? 83   GLY B C   1 
ATOM   4027 O  O   . GLY B  1 52  ? 10.65812 36.33838  7.69710   1.000 20.23761 ? 83   GLY B O   1 
ATOM   4028 N  N   . SER B  1 53  ? 10.99560 36.98124  5.55907   1.000 16.51045 ? 84   SER B N   1 
ATOM   4029 C  CA  . SER B  1 53  ? 10.33712 35.82411  4.96743   1.000 17.05791 ? 84   SER B CA  1 
ATOM   4030 C  C   . SER B  1 53  ? 11.36298 34.97664  4.22681   1.000 18.46188 ? 84   SER B C   1 
ATOM   4031 O  O   . SER B  1 53  ? 12.05500 35.47996  3.33517   1.000 18.17381 ? 84   SER B O   1 
ATOM   4032 C  CB  . SER B  1 53  ? 9.22047  36.26524  4.01939   1.000 20.23784 ? 84   SER B CB  1 
ATOM   4033 O  OG  . SER B  1 53  ? 8.63638  35.14205  3.38518   1.000 24.89705 ? 84   SER B OG  1 
ATOM   4034 N  N   . ILE B  1 54  ? 11.46133 33.70468  4.60687   1.000 16.46507 ? 85   ILE B N   1 
ATOM   4035 C  CA  . ILE B  1 54  ? 12.33420 32.73206  3.94221   1.000 15.12498 ? 85   ILE B CA  1 
ATOM   4036 C  C   . ILE B  1 54  ? 11.52030 31.99991  2.88768   1.000 17.26348 ? 85   ILE B C   1 
ATOM   4037 O  O   . ILE B  1 54  ? 10.45324 31.46197  3.18635   1.000 18.22615 ? 85   ILE B O   1 
ATOM   4038 C  CB  . ILE B  1 54  ? 12.91791 31.73650  4.96058   1.000 16.89385 ? 85   ILE B CB  1 
ATOM   4039 C  CG1 . ILE B  1 54  ? 13.90379 32.43331  5.88661   1.000 17.61037 ? 85   ILE B CG1 1 
ATOM   4040 C  CG2 . ILE B  1 54  ? 13.57813 30.54678  4.24009   1.000 18.05415 ? 85   ILE B CG2 1 
ATOM   4041 C  CD1 . ILE B  1 54  ? 14.33386 31.56146  7.05052   1.000 18.95164 ? 85   ILE B CD1 1 
ATOM   4042 N  N   . PHE B  1 55  ? 12.03222 31.94804  1.65700   1.000 15.78521 ? 86   PHE B N   1 
ATOM   4043 C  CA  . PHE B  1 55  ? 11.33086 31.30315  0.55284   1.000 16.62087 ? 86   PHE B CA  1 
ATOM   4044 C  C   . PHE B  1 55  ? 11.88071 29.89533  0.38330   1.000 17.02269 ? 86   PHE B C   1 
ATOM   4045 O  O   . PHE B  1 55  ? 13.04521 29.71602  0.00761   1.000 17.85965 ? 86   PHE B O   1 
ATOM   4046 C  CB  . PHE B  1 55  ? 11.48346 32.10538  -0.73342  1.000 15.98251 ? 86   PHE B CB  1 
ATOM   4047 C  CG  . PHE B  1 55  ? 10.75345 33.41312  -0.69919  1.000 16.10328 ? 86   PHE B CG  1 
ATOM   4048 C  CD1 . PHE B  1 55  ? 11.28592 34.50286  -0.02485  1.000 17.29668 ? 86   PHE B CD1 1 
ATOM   4049 C  CD2 . PHE B  1 55  ? 9.51920  33.54161  -1.31077  1.000 18.41143 ? 86   PHE B CD2 1 
ATOM   4050 C  CE1 . PHE B  1 55  ? 10.60302 35.72196  0.02413   1.000 17.80352 ? 86   PHE B CE1 1 
ATOM   4051 C  CE2 . PHE B  1 55  ? 8.82648  34.75953  -1.27050  1.000 18.60665 ? 86   PHE B CE2 1 
ATOM   4052 C  CZ  . PHE B  1 55  ? 9.37737  35.85388  -0.59979  1.000 19.87149 ? 86   PHE B CZ  1 
ATOM   4053 N  N   . THR B  1 56  ? 11.04683 28.90100  0.65754   1.000 16.87924 ? 87   THR B N   1 
ATOM   4054 C  CA  . THR B  1 56  ? 11.51743 27.52394  0.65125   1.000 14.92616 ? 87   THR B CA  1 
ATOM   4055 C  C   . THR B  1 56  ? 11.42712 26.87087  -0.72221  1.000 14.61251 ? 87   THR B C   1 
ATOM   4056 O  O   . THR B  1 56  ? 11.96639 25.77265  -0.89685  1.000 16.99634 ? 87   THR B O   1 
ATOM   4057 C  CB  . THR B  1 56  ? 10.74654 26.69613  1.68579   1.000 17.65924 ? 87   THR B CB  1 
ATOM   4058 O  OG1 . THR B  1 56  ? 9.34628  26.69798  1.37021   1.000 18.88283 ? 87   THR B OG1 1 
ATOM   4059 C  CG2 . THR B  1 56  ? 10.95838 27.27416  3.07590   1.000 20.88054 ? 87   THR B CG2 1 
ATOM   4060 N  N   . SER B  1 57  ? 10.76485 27.51734  -1.69263  1.000 16.42533 ? 88   SER B N   1 
ATOM   4061 C  CA  . SER B  1 57  ? 10.68941 27.02832  -3.07219  1.000 17.83078 ? 88   SER B CA  1 
ATOM   4062 C  C   . SER B  1 57  ? 10.96696 28.19075  -4.03105  1.000 16.63027 ? 88   SER B C   1 
ATOM   4063 O  O   . SER B  1 57  ? 10.12192 28.58197  -4.83312  1.000 16.11387 ? 88   SER B O   1 
ATOM   4064 C  CB  . SER B  1 57  ? 9.32849  26.39456  -3.38966  1.000 17.08240 ? 88   SER B CB  1 
ATOM   4065 O  OG  . SER B  1 57  ? 9.25805  25.05240  -2.91900  1.000 18.22361 ? 88   SER B OG  1 
ATOM   4066 N  N   . ALA B  1 58  ? 12.16903 28.74817  -3.94241  1.000 14.61742 ? 89   ALA B N   1 
ATOM   4067 C  CA  . ALA B  1 58  ? 12.58010 29.86537  -4.79183  1.000 15.58345 ? 89   ALA B CA  1 
ATOM   4068 C  C   . ALA B  1 58  ? 13.39777 29.34891  -5.96810  1.000 15.88843 ? 89   ALA B C   1 
ATOM   4069 O  O   . ALA B  1 58  ? 14.34711 28.58850  -5.77806  1.000 16.98343 ? 89   ALA B O   1 
ATOM   4070 C  CB  . ALA B  1 58  ? 13.40347 30.88387  -4.00239  1.000 16.69308 ? 89   ALA B CB  1 
ATOM   4071 N  N   . TYR B  1 59  ? 13.05265 29.78999  -7.17556  1.000 15.42363 ? 90   TYR B N   1 
ATOM   4072 C  CA  . TYR B  1 59  ? 13.71730 29.32189  -8.38971  1.000 14.01748 ? 90   TYR B CA  1 
ATOM   4073 C  C   . TYR B  1 59  ? 14.32243 30.47011  -9.17510  1.000 15.22109 ? 90   TYR B C   1 
ATOM   4074 O  O   . TYR B  1 59  ? 13.70915 31.53589  -9.30678  1.000 18.93814 ? 90   TYR B O   1 
ATOM   4075 C  CB  . TYR B  1 59  ? 12.73835 28.58659  -9.29923  1.000 15.47680 ? 90   TYR B CB  1 
ATOM   4076 C  CG  . TYR B  1 59  ? 12.22296 27.32798  -8.66233  1.000 15.41448 ? 90   TYR B CG  1 
ATOM   4077 C  CD1 . TYR B  1 59  ? 12.96213 26.15288  -8.71336  1.000 14.41575 ? 90   TYR B CD1 1 
ATOM   4078 C  CD2 . TYR B  1 59  ? 11.01312 27.32098  -7.97734  1.000 17.16013 ? 90   TYR B CD2 1 
ATOM   4079 C  CE1 . TYR B  1 59  ? 12.49936 24.99037  -8.12105  1.000 13.54457 ? 90   TYR B CE1 1 
ATOM   4080 C  CE2 . TYR B  1 59  ? 10.53919 26.16574  -7.37245  1.000 17.20246 ? 90   TYR B CE2 1 
ATOM   4081 C  CZ  . TYR B  1 59  ? 11.28951 25.00596  -7.44947  1.000 15.80415 ? 90   TYR B CZ  1 
ATOM   4082 O  OH  . TYR B  1 59  ? 10.84834 23.84262  -6.88752  1.000 17.78136 ? 90   TYR B OH  1 
ATOM   4083 N  N   . VAL B  1 60  ? 15.50617 30.22886  -9.74466  1.000 14.92770 ? 91   VAL B N   1 
ATOM   4084 C  CA  . VAL B  1 60  ? 16.03479 31.12241  -10.77037 1.000 17.59853 ? 91   VAL B CA  1 
ATOM   4085 C  C   . VAL B  1 60  ? 15.64915 30.59252  -12.14819 1.000 13.87980 ? 91   VAL B C   1 
ATOM   4086 O  O   . VAL B  1 60  ? 15.29628 29.42712  -12.32369 1.000 15.93433 ? 91   VAL B O   1 
ATOM   4087 C  CB  . VAL B  1 60  ? 17.55753 31.30247  -10.65162 1.000 15.36177 ? 91   VAL B CB  1 
ATOM   4088 C  CG1 . VAL B  1 60  ? 17.88419 32.05867  -9.38069  1.000 14.58229 ? 91   VAL B CG1 1 
ATOM   4089 C  CG2 . VAL B  1 60  ? 18.26871 29.93636  -10.66152 1.000 14.62296 ? 91   VAL B CG2 1 
ATOM   4090 N  N   . ALA B  1 61  ? 15.72742 31.47457  -13.15017 1.000 14.87533 ? 92   ALA B N   1 
ATOM   4091 C  CA  . ALA B  1 61  ? 15.16167 31.16545  -14.45765 1.000 15.01999 ? 92   ALA B CA  1 
ATOM   4092 C  C   . ALA B  1 61  ? 16.05987 30.29198  -15.31201 1.000 18.06495 ? 92   ALA B C   1 
ATOM   4093 O  O   . ALA B  1 61  ? 15.62267 29.85169  -16.37967 1.000 16.66634 ? 92   ALA B O   1 
ATOM   4094 C  CB  . ALA B  1 61  ? 14.84750 32.46306  -15.20782 1.000 17.02793 ? 92   ALA B CB  1 
ATOM   4095 N  N   . HIS B  1 62  ? 17.28486 30.02204  -14.86742 1.000 16.05923 ? 93   HIS B N   1 
ATOM   4096 C  CA  . HIS B  1 62  ? 18.20864 29.16246  -15.58658 1.000 16.55593 ? 93   HIS B CA  1 
ATOM   4097 C  C   . HIS B  1 62  ? 19.21647 28.63091  -14.58721 1.000 16.26163 ? 93   HIS B C   1 
ATOM   4098 O  O   . HIS B  1 62  ? 19.56073 29.33853  -13.63465 1.000 16.89132 ? 93   HIS B O   1 
ATOM   4099 C  CB  . HIS B  1 62  ? 18.92203 29.94325  -16.69807 1.000 17.33821 ? 93   HIS B CB  1 
ATOM   4100 C  CG  . HIS B  1 62  ? 19.48182 29.07861  -17.77504 1.000 16.86877 ? 93   HIS B CG  1 
ATOM   4101 N  ND1 . HIS B  1 62  ? 18.68227 28.42250  -18.68762 1.000 16.18342 ? 93   HIS B ND1 1 
ATOM   4102 C  CD2 . HIS B  1 62  ? 20.75823 28.73958  -18.07375 1.000 15.88352 ? 93   HIS B CD2 1 
ATOM   4103 C  CE1 . HIS B  1 62  ? 19.44480 27.73701  -19.51927 1.000 15.32887 ? 93   HIS B CE1 1 
ATOM   4104 N  NE2 . HIS B  1 62  ? 20.70880 27.91694  -19.17129 1.000 16.21198 ? 93   HIS B NE2 1 
ATOM   4105 N  N   . PRO B  1 63  ? 19.73745 27.41346  -14.78548 1.000 15.80367 ? 94   PRO B N   1 
ATOM   4106 C  CA  . PRO B  1 63  ? 20.62787 26.84512  -13.76369 1.000 16.72476 ? 94   PRO B CA  1 
ATOM   4107 C  C   . PRO B  1 63  ? 22.09693 27.25991  -13.89233 1.000 16.58225 ? 94   PRO B C   1 
ATOM   4108 O  O   . PRO B  1 63  ? 22.95639 26.60888  -13.29915 1.000 17.29512 ? 94   PRO B O   1 
ATOM   4109 C  CB  . PRO B  1 63  ? 20.44489 25.33184  -13.94901 1.000 17.15609 ? 94   PRO B CB  1 
ATOM   4110 C  CG  . PRO B  1 63  ? 20.12053 25.18358  -15.41412 1.000 16.62823 ? 94   PRO B CG  1 
ATOM   4111 C  CD  . PRO B  1 63  ? 19.29146 26.40733  -15.76354 1.000 14.80834 ? 94   PRO B CD  1 
ATOM   4112 N  N   . PHE B  1 64  ? 22.41577 28.32855  -14.62647 1.000 16.58414 ? 95   PHE B N   1 
ATOM   4113 C  CA  . PHE B  1 64  ? 23.75131 28.92749  -14.50223 1.000 16.70917 ? 95   PHE B CA  1 
ATOM   4114 C  C   . PHE B  1 64  ? 23.75149 30.41047  -14.87867 1.000 19.19011 ? 95   PHE B C   1 
ATOM   4115 O  O   . PHE B  1 64  ? 22.77921 30.90616  -15.44533 1.000 17.88342 ? 95   PHE B O   1 
ATOM   4116 C  CB  . PHE B  1 64  ? 24.81733 28.15402  -15.30906 1.000 17.32130 ? 95   PHE B CB  1 
ATOM   4117 C  CG  . PHE B  1 64  ? 24.54815 28.02707  -16.79084 1.000 16.30556 ? 95   PHE B CG  1 
ATOM   4118 C  CD1 . PHE B  1 64  ? 24.88427 29.06129  -17.66524 1.000 19.63705 ? 95   PHE B CD1 1 
ATOM   4119 C  CD2 . PHE B  1 64  ? 24.03878 26.85103  -17.31284 1.000 17.31804 ? 95   PHE B CD2 1 
ATOM   4120 C  CE1 . PHE B  1 64  ? 24.65867 28.93903  -19.03290 1.000 17.46117 ? 95   PHE B CE1 1 
ATOM   4121 C  CE2 . PHE B  1 64  ? 23.81653 26.71110  -18.67826 1.000 16.86343 ? 95   PHE B CE2 1 
ATOM   4122 C  CZ  . PHE B  1 64  ? 24.13434 27.76759  -19.54580 1.000 16.65123 ? 95   PHE B CZ  1 
HETATM 4123 N  N   . OSE B  1 65  ? 24.86662 31.08634  -14.57731 1.000 24.08944 ? 96   OSE B N   1 
HETATM 4124 C  CA  . OSE B  1 65  ? 24.88395 32.54428  -14.26521 1.000 21.39121 ? 96   OSE B CA  1 
HETATM 4125 C  CB  . OSE B  1 65  ? 26.25045 33.01326  -13.87714 1.000 30.09043 ? 96   OSE B CB  1 
HETATM 4126 O  OG  . OSE B  1 65  ? 27.08226 32.41356  -14.82233 1.000 36.26674 ? 96   OSE B OG  1 
HETATM 4127 C  C   . OSE B  1 65  ? 24.38988 33.43651  -15.40260 1.000 18.98747 ? 96   OSE B C   1 
HETATM 4128 O  O   . OSE B  1 65  ? 23.52646 34.24240  -15.10124 1.000 17.81715 ? 96   OSE B O   1 
HETATM 4129 S  S   . OSE B  1 65  ? 27.89798 31.23889  -14.24476 1.000 31.63622 ? 96   OSE B S   1 
HETATM 4130 O  O1S . OSE B  1 65  ? 28.02252 30.28169  -15.32320 1.000 38.27327 ? 96   OSE B O1S 1 
HETATM 4131 O  O2S . OSE B  1 65  ? 29.14819 31.88831  -13.89691 1.000 36.56184 ? 96   OSE B O2S 1 
HETATM 4132 O  O3S . OSE B  1 65  ? 27.18916 30.72627  -13.10568 1.000 28.97233 ? 96   OSE B O3S 1 
ATOM   4133 N  N   . GLY B  1 66  ? 25.00852 33.41862  -16.57967 1.000 21.25284 ? 97   GLY B N   1 
ATOM   4134 C  CA  . GLY B  1 66  ? 24.67580 34.42639  -17.58358 1.000 20.37416 ? 97   GLY B CA  1 
ATOM   4135 C  C   . GLY B  1 66  ? 23.18647 34.53637  -17.87800 1.000 18.87077 ? 97   GLY B C   1 
ATOM   4136 O  O   . GLY B  1 66  ? 22.58185 35.62605  -17.76568 1.000 17.81019 ? 97   GLY B O   1 
ATOM   4137 N  N   . PRO B  1 67  ? 22.58496 33.41405  -18.27209 1.000 16.48860 ? 98   PRO B N   1 
ATOM   4138 C  CA  . PRO B  1 67  ? 21.14003 33.42417  -18.53864 1.000 15.47647 ? 98   PRO B CA  1 
ATOM   4139 C  C   . PRO B  1 67  ? 20.30882 33.71120  -17.30324 1.000 17.75165 ? 98   PRO B C   1 
ATOM   4140 O  O   . PRO B  1 67  ? 19.26353 34.36595  -17.40199 1.000 17.09678 ? 98   PRO B O   1 
ATOM   4141 C  CB  . PRO B  1 67  ? 20.87574 32.01604  -19.09397 1.000 16.84567 ? 98   PRO B CB  1 
ATOM   4142 C  CG  . PRO B  1 67  ? 22.20399 31.56908  -19.63987 1.000 17.99310 ? 98   PRO B CG  1 
ATOM   4143 C  CD  . PRO B  1 67  ? 23.23310 32.17516  -18.73939 1.000 18.16000 ? 98   PRO B CD  1 
ATOM   4144 N  N   . SER B  1 68  ? 20.75429 33.26643  -16.13251 1.000 17.14180 ? 99   SER B N   1 
ATOM   4145 C  CA  . SER B  1 68  ? 20.02894 33.61142  -14.91297 1.000 16.12417 ? 99   SER B CA  1 
ATOM   4146 C  C   . SER B  1 68  ? 20.07206 35.11048  -14.64370 1.000 17.90161 ? 99   SER B C   1 
ATOM   4147 O  O   . SER B  1 68  ? 19.05206 35.71992  -14.29016 1.000 17.82169 ? 99   SER B O   1 
ATOM   4148 C  CB  . SER B  1 68  ? 20.61449 32.84153  -13.73409 1.000 18.26167 ? 99   SER B CB  1 
ATOM   4149 O  OG  . SER B  1 68  ? 20.02041 33.25115  -12.51128 1.000 16.95194 ? 99   SER B OG  1 
ATOM   4150 N  N   . ARG B  1 69  ? 21.24952 35.71765  -14.78802 1.000 17.31163 ? 100  ARG B N   1 
ATOM   4151 C  CA  . ARG B  1 69  ? 21.37824 37.14460  -14.53591 1.000 17.37892 ? 100  ARG B CA  1 
ATOM   4152 C  C   . ARG B  1 69  ? 20.64916 37.95184  -15.59696 1.000 16.62171 ? 100  ARG B C   1 
ATOM   4153 O  O   . ARG B  1 69  ? 20.02266 38.96856  -15.28834 1.000 17.50713 ? 100  ARG B O   1 
ATOM   4154 C  CB  . ARG B  1 69  ? 22.85931 37.50998  -14.46152 1.000 16.57503 ? 100  ARG B CB  1 
ATOM   4155 C  CG  . ARG B  1 69  ? 23.50951 36.92393  -13.20258 1.000 16.32759 ? 100  ARG B CG  1 
ATOM   4156 C  CD  . ARG B  1 69  ? 25.00180 36.69213  -13.35117 1.000 17.38064 ? 100  ARG B CD  1 
ATOM   4157 N  NE  . ARG B  1 69  ? 25.50449 35.94363  -12.20689 1.000 16.66922 ? 100  ARG B NE  1 
ATOM   4158 C  CZ  . ARG B  1 69  ? 25.86887 36.49933  -11.06069 1.000 17.29727 ? 100  ARG B CZ  1 
ATOM   4159 N  NH1 . ARG B  1 69  ? 25.89782 37.81846  -10.90893 1.000 17.94474 ? 100  ARG B NH1 1 
ATOM   4160 N  NH2 . ARG B  1 69  ? 26.22024 35.71443  -10.04305 1.000 17.09245 ? 100  ARG B NH2 1 
ATOM   4161 N  N   . SER B  1 70  ? 20.69764 37.50255  -16.85125 1.000 17.68515 ? 101  SER B N   1 
ATOM   4162 C  CA  A SER B  1 70  ? 19.89910 38.16178  -17.87639 0.298 19.51238 ? 101  SER B CA  1 
ATOM   4163 C  CA  B SER B  1 70  ? 19.89354 38.13614  -17.89242 0.702 19.57368 ? 101  SER B CA  1 
ATOM   4164 C  C   . SER B  1 70  ? 18.41900 38.13289  -17.51107 1.000 20.08206 ? 101  SER B C   1 
ATOM   4165 O  O   . SER B  1 70  ? 17.72138 39.14366  -17.65747 1.000 19.95688 ? 101  SER B O   1 
ATOM   4166 C  CB  A SER B  1 70  ? 20.14311 37.51352  -19.23939 0.298 18.32743 ? 101  SER B CB  1 
ATOM   4167 C  CB  B SER B  1 70  ? 20.10917 37.41419  -19.22584 0.702 18.27998 ? 101  SER B CB  1 
ATOM   4168 O  OG  A SER B  1 70  ? 19.55616 36.23092  -19.31458 0.298 18.80632 ? 101  SER B OG  1 
ATOM   4169 O  OG  B SER B  1 70  ? 19.20722 37.87072  -20.22664 0.702 18.64973 ? 101  SER B OG  1 
ATOM   4170 N  N   . ALA B  1 71  ? 17.93358 37.00123  -16.99489 1.000 16.98467 ? 102  ALA B N   1 
ATOM   4171 C  CA  . ALA B  1 71  ? 16.52704 36.90014  -16.60439 1.000 17.32449 ? 102  ALA B CA  1 
ATOM   4172 C  C   . ALA B  1 71  ? 16.19405 37.82615  -15.44420 1.000 17.11307 ? 102  ALA B C   1 
ATOM   4173 O  O   . ALA B  1 71  ? 15.10833 38.41761  -15.40950 1.000 18.43565 ? 102  ALA B O   1 
ATOM   4174 C  CB  . ALA B  1 71  ? 16.19430 35.45926  -16.22690 1.000 16.99363 ? 102  ALA B CB  1 
ATOM   4175 N  N   . ILE B  1 72  ? 17.10101 37.94573  -14.47283 1.000 17.03590 ? 103  ILE B N   1 
ATOM   4176 C  CA  . ILE B  1 72  ? 16.84770 38.82294  -13.33296 1.000 16.93118 ? 103  ILE B CA  1 
ATOM   4177 C  C   . ILE B  1 72  ? 16.67146 40.26114  -13.80048 1.000 16.14153 ? 103  ILE B C   1 
ATOM   4178 O  O   . ILE B  1 72  ? 15.71422 40.94006  -13.41662 1.000 18.26561 ? 103  ILE B O   1 
ATOM   4179 C  CB  . ILE B  1 72  ? 17.97492 38.69716  -12.29439 1.000 15.75512 ? 103  ILE B CB  1 
ATOM   4180 C  CG1 . ILE B  1 72  ? 17.83349 37.36572  -11.55759 1.000 17.99161 ? 103  ILE B CG1 1 
ATOM   4181 C  CG2 . ILE B  1 72  ? 17.93482 39.86694  -11.30057 1.000 20.39281 ? 103  ILE B CG2 1 
ATOM   4182 C  CD1 . ILE B  1 72  ? 19.04902 36.99248  -10.68778 1.000 21.20982 ? 103  ILE B CD1 1 
ATOM   4183 N  N   . LEU B  1 73  ? 17.58662 40.74346  -14.64694 1.000 16.57915 ? 104  LEU B N   1 
ATOM   4184 C  CA  . LEU B  1 73  ? 17.53512 42.15680  -15.00551 1.000 19.26930 ? 104  LEU B CA  1 
ATOM   4185 C  C   . LEU B  1 73  ? 16.52851 42.44519  -16.11849 1.000 18.60380 ? 104  LEU B C   1 
ATOM   4186 O  O   . LEU B  1 73  ? 15.93880 43.52960  -16.13097 1.000 18.63104 ? 104  LEU B O   1 
ATOM   4187 C  CB  . LEU B  1 73  ? 18.93213 42.65919  -15.38032 1.000 19.07052 ? 104  LEU B CB  1 
ATOM   4188 C  CG  . LEU B  1 73  ? 19.78202 43.01225  -14.14406 1.000 26.01216 ? 104  LEU B CG  1 
ATOM   4189 C  CD1 . LEU B  1 73  ? 21.18717 43.41631  -14.51378 1.000 27.28165 ? 104  LEU B CD1 1 
ATOM   4190 C  CD2 . LEU B  1 73  ? 19.14483 44.13308  -13.32233 1.000 26.91811 ? 104  LEU B CD2 1 
ATOM   4191 N  N   . THR B  1 74  ? 16.28747 41.50386  -17.03827 1.000 17.47925 ? 105  THR B N   1 
ATOM   4192 C  CA  . THR B  1 74  ? 15.27369 41.73482  -18.06751 1.000 19.71296 ? 105  THR B CA  1 
ATOM   4193 C  C   . THR B  1 74  ? 13.87448 41.31900  -17.64135 1.000 19.93723 ? 105  THR B C   1 
ATOM   4194 O  O   . THR B  1 74  ? 12.89807 41.75083  -18.26728 1.000 19.96911 ? 105  THR B O   1 
ATOM   4195 C  CB  . THR B  1 74  ? 15.57554 40.96632  -19.36144 1.000 19.84300 ? 105  THR B CB  1 
ATOM   4196 O  OG1 . THR B  1 74  ? 15.43764 39.55266  -19.12512 1.000 18.88562 ? 105  THR B OG1 1 
ATOM   4197 C  CG2 . THR B  1 74  ? 16.96737 41.31157  -19.92103 1.000 19.89019 ? 105  THR B CG2 1 
ATOM   4198 N  N   . GLY B  1 75  ? 13.75056 40.46391  -16.63135 1.000 17.12269 ? 106  GLY B N   1 
ATOM   4199 C  CA  . GLY B  1 75  ? 12.44747 39.94577  -16.28560 1.000 17.61487 ? 106  GLY B CA  1 
ATOM   4200 C  C   . GLY B  1 75  ? 11.87725 38.94188  -17.25727 1.000 18.30645 ? 106  GLY B C   1 
ATOM   4201 O  O   . GLY B  1 75  ? 10.68539 38.63447  -17.17125 1.000 18.70541 ? 106  GLY B O   1 
ATOM   4202 N  N   . ARG B  1 76  ? 12.69048 38.38876  -18.16418 1.000 16.68181 ? 107  ARG B N   1 
ATOM   4203 C  CA  A ARG B  1 76  ? 12.21565 37.39720  -19.11789 0.282 17.97190 ? 107  ARG B CA  1 
ATOM   4204 C  CA  B ARG B  1 76  ? 12.22498 37.40522  -19.13204 0.718 17.91158 ? 107  ARG B CA  1 
ATOM   4205 C  C   . ARG B  1 76  ? 13.11978 36.17439  -19.11063 1.000 19.11267 ? 107  ARG B C   1 
ATOM   4206 O  O   . ARG B  1 76  ? 14.32193 36.26951  -18.84482 1.000 19.62579 ? 107  ARG B O   1 
ATOM   4207 C  CB  A ARG B  1 76  ? 12.14623 37.97120  -20.53680 0.282 19.43584 ? 107  ARG B CB  1 
ATOM   4208 C  CB  B ARG B  1 76  ? 12.20928 37.99064  -20.54967 0.718 19.38179 ? 107  ARG B CB  1 
ATOM   4209 C  CG  A ARG B  1 76  ? 11.25540 39.19207  -20.63918 0.282 20.29269 ? 107  ARG B CG  1 
ATOM   4210 C  CG  B ARG B  1 76  ? 11.41140 39.28338  -20.66146 0.718 20.18169 ? 107  ARG B CG  1 
ATOM   4211 C  CD  A ARG B  1 76  ? 10.71058 39.37313  -22.04273 0.282 23.40213 ? 107  ARG B CD  1 
ATOM   4212 C  CD  B ARG B  1 76  ? 11.31155 39.72029  -22.10914 0.718 21.81942 ? 107  ARG B CD  1 
ATOM   4213 N  NE  A ARG B  1 76  ? 10.05442 38.17439  -22.55331 0.282 22.73315 ? 107  ARG B NE  1 
ATOM   4214 N  NE  B ARG B  1 76  ? 10.39312 38.87762  -22.86517 0.718 25.38308 ? 107  ARG B NE  1 
ATOM   4215 C  CZ  A ARG B  1 76  ? 8.86984  37.72942  -22.15447 0.282 25.02903 ? 107  ARG B CZ  1 
ATOM   4216 C  CZ  B ARG B  1 76  ? 10.31345 38.86722  -24.18858 0.718 25.35807 ? 107  ARG B CZ  1 
ATOM   4217 N  NH1 A ARG B  1 76  ? 8.20412  38.31320  -21.17174 0.282 25.97287 ? 107  ARG B NH1 1 
ATOM   4218 N  NH1 B ARG B  1 76  ? 11.10600 39.62341  -24.93510 0.718 25.07934 ? 107  ARG B NH1 1 
ATOM   4219 N  NH2 A ARG B  1 76  ? 8.33647  36.67457  -22.76023 0.282 24.02947 ? 107  ARG B NH2 1 
ATOM   4220 N  NH2 B ARG B  1 76  ? 9.41183  38.08731  -24.77674 0.718 22.72413 ? 107  ARG B NH2 1 
ATOM   4221 N  N   . TYR B  1 77  ? 12.52290 35.01793  -19.41113 1.000 17.42242 ? 108  TYR B N   1 
ATOM   4222 C  CA  . TYR B  1 77  ? 13.31566 33.80912  -19.57760 1.000 16.25162 ? 108  TYR B CA  1 
ATOM   4223 C  C   . TYR B  1 77  ? 14.36063 34.04652  -20.66127 1.000 20.68757 ? 108  TYR B C   1 
ATOM   4224 O  O   . TYR B  1 77  ? 14.07963 34.73598  -21.64875 1.000 20.51203 ? 108  TYR B O   1 
ATOM   4225 C  CB  . TYR B  1 77  ? 12.44612 32.61718  -19.97519 1.000 18.27125 ? 108  TYR B CB  1 
ATOM   4226 C  CG  . TYR B  1 77  ? 11.73080 31.95026  -18.82941 1.000 15.68194 ? 108  TYR B CG  1 
ATOM   4227 C  CD1 . TYR B  1 77  ? 12.41311 31.08404  -17.97051 1.000 17.19184 ? 108  TYR B CD1 1 
ATOM   4228 C  CD2 . TYR B  1 77  ? 10.37242 32.15518  -18.62672 1.000 18.66764 ? 108  TYR B CD2 1 
ATOM   4229 C  CE1 . TYR B  1 77  ? 11.74985 30.44502  -16.92238 1.000 16.05727 ? 108  TYR B CE1 1 
ATOM   4230 C  CE2 . TYR B  1 77  ? 9.70296  31.52744  -17.58432 1.000 19.08592 ? 108  TYR B CE2 1 
ATOM   4231 C  CZ  . TYR B  1 77  ? 10.39754 30.67514  -16.74098 1.000 20.03371 ? 108  TYR B CZ  1 
ATOM   4232 O  OH  . TYR B  1 77  ? 9.73237  30.05302  -15.69643 1.000 18.07428 ? 108  TYR B OH  1 
ATOM   4233 N  N   . PRO B  1 78  ? 15.57218 33.51190  -20.50433 1.000 18.80538 ? 109  PRO B N   1 
ATOM   4234 C  CA  . PRO B  1 78  ? 16.62666 33.78640  -21.49321 1.000 17.99992 ? 109  PRO B CA  1 
ATOM   4235 C  C   . PRO B  1 78  ? 16.34370 33.17054  -22.84561 1.000 19.63319 ? 109  PRO B C   1 
ATOM   4236 O  O   . PRO B  1 78  ? 16.93095 33.61103  -23.84231 1.000 19.54803 ? 109  PRO B O   1 
ATOM   4237 C  CB  . PRO B  1 78  ? 17.87892 33.18218  -20.84448 1.000 17.53156 ? 109  PRO B CB  1 
ATOM   4238 C  CG  . PRO B  1 78  ? 17.32568 32.08067  -19.93336 1.000 16.36245 ? 109  PRO B CG  1 
ATOM   4239 C  CD  . PRO B  1 78  ? 16.04781 32.65645  -19.39804 1.000 17.73331 ? 109  PRO B CD  1 
ATOM   4240 N  N   . HIS B  1 79  ? 15.44758 32.18465  -22.90665 1.000 17.99653 ? 110  HIS B N   1 
ATOM   4241 C  CA  . HIS B  1 79  ? 15.01571 31.58366  -24.16453 1.000 18.23993 ? 110  HIS B CA  1 
ATOM   4242 C  C   . HIS B  1 79  ? 14.16360 32.53232  -24.98892 1.000 21.10868 ? 110  HIS B C   1 
ATOM   4243 O  O   . HIS B  1 79  ? 13.95165 32.27822  -26.17926 1.000 22.21068 ? 110  HIS B O   1 
ATOM   4244 C  CB  . HIS B  1 79  ? 14.21334 30.31997  -23.88609 1.000 20.00895 ? 110  HIS B CB  1 
ATOM   4245 C  CG  . HIS B  1 79  ? 14.72976 29.53938  -22.72293 1.000 18.35213 ? 110  HIS B CG  1 
ATOM   4246 N  ND1 . HIS B  1 79  ? 14.56667 29.95299  -21.41658 1.000 21.67252 ? 110  HIS B ND1 1 
ATOM   4247 C  CD2 . HIS B  1 79  ? 15.41691 28.37667  -22.67054 1.000 19.16829 ? 110  HIS B CD2 1 
ATOM   4248 C  CE1 . HIS B  1 79  ? 15.13981 29.07824  -20.60854 1.000 19.25694 ? 110  HIS B CE1 1 
ATOM   4249 N  NE2 . HIS B  1 79  ? 15.66146 28.11064  -21.34357 1.000 19.58868 ? 110  HIS B NE2 1 
ATOM   4250 N  N   . LEU B  1 80  ? 13.64056 33.58671  -24.37382 1.000 20.21575 ? 111  LEU B N   1 
ATOM   4251 C  CA  . LEU B  1 80  ? 12.86631 34.58993  -25.08871 1.000 20.34838 ? 111  LEU B CA  1 
ATOM   4252 C  C   . LEU B  1 80  ? 13.71220 35.77585  -25.53214 1.000 23.59175 ? 111  LEU B C   1 
ATOM   4253 O  O   . LEU B  1 80  ? 13.28921 36.52650  -26.42501 1.000 25.14718 ? 111  LEU B O   1 
ATOM   4254 C  CB  . LEU B  1 80  ? 11.71234 35.08106  -24.20595 1.000 20.89342 ? 111  LEU B CB  1 
ATOM   4255 C  CG  . LEU B  1 80  ? 10.45269 34.20854  -24.12609 1.000 25.50619 ? 111  LEU B CG  1 
ATOM   4256 C  CD1 . LEU B  1 80  ? 9.74030  34.24602  -25.47380 1.000 29.82366 ? 111  LEU B CD1 1 
ATOM   4257 C  CD2 . LEU B  1 80  ? 10.72894 32.76530  -23.71807 1.000 29.54321 ? 111  LEU B CD2 1 
ATOM   4258 N  N   . THR B  1 81  ? 14.89168 35.95570  -24.93864 1.000 21.67102 ? 112  THR B N   1 
ATOM   4259 C  CA  . THR B  1 81  ? 15.76986 37.08080  -25.23332 1.000 21.39502 ? 112  THR B CA  1 
ATOM   4260 C  C   . THR B  1 81  ? 17.01709 36.66513  -25.99847 1.000 22.29090 ? 112  THR B C   1 
ATOM   4261 O  O   . THR B  1 81  ? 17.84463 37.52899  -26.32485 1.000 24.43299 ? 112  THR B O   1 
ATOM   4262 C  CB  . THR B  1 81  ? 16.17001 37.79185  -23.93556 1.000 21.55439 ? 112  THR B CB  1 
ATOM   4263 O  OG1 . THR B  1 81  ? 16.81699 36.85237  -23.05657 1.000 20.24813 ? 112  THR B OG1 1 
ATOM   4264 C  CG2 . THR B  1 81  ? 14.92964 38.35856  -23.23794 1.000 22.22945 ? 112  THR B CG2 1 
ATOM   4265 N  N   . GLY B  1 82  ? 17.17878 35.37234  -26.28370 1.000 19.81977 ? 113  GLY B N   1 
ATOM   4266 C  CA  . GLY B  1 82  ? 18.33399 34.90572  -27.03107 1.000 22.30752 ? 113  GLY B CA  1 
ATOM   4267 C  C   . GLY B  1 82  ? 19.59580 34.73813  -26.21786 1.000 21.69832 ? 113  GLY B C   1 
ATOM   4268 O  O   . GLY B  1 82  ? 20.68781 34.64660  -26.79133 1.000 21.33441 ? 113  GLY B O   1 
ATOM   4269 N  N   . THR B  1 83  ? 19.48150 34.65837  -24.89028 1.000 18.63460 ? 114  THR B N   1 
ATOM   4270 C  CA  . THR B  1 83  ? 20.63180 34.76558  -24.00308 1.000 16.86029 ? 114  THR B CA  1 
ATOM   4271 C  C   . THR B  1 83  ? 20.76663 33.54121  -23.09628 1.000 17.71907 ? 114  THR B C   1 
ATOM   4272 O  O   . THR B  1 83  ? 21.22641 33.65481  -21.95544 1.000 18.24433 ? 114  THR B O   1 
ATOM   4273 C  CB  . THR B  1 83  ? 20.54198 36.04856  -23.17398 1.000 19.80270 ? 114  THR B CB  1 
ATOM   4274 O  OG1 . THR B  1 83  ? 19.29988 36.05791  -22.45139 1.000 20.62477 ? 114  THR B OG1 1 
ATOM   4275 C  CG2 . THR B  1 83  ? 20.57404 37.28972  -24.08969 1.000 18.35865 ? 114  THR B CG2 1 
ATOM   4276 N  N   . ALA B  1 84  ? 20.40117 32.36169  -23.60089 1.000 19.25692 ? 115  ALA B N   1 
ATOM   4277 C  CA  . ALA B  1 84  ? 20.40614 31.14237  -22.79442 1.000 18.26739 ? 115  ALA B CA  1 
ATOM   4278 C  C   . ALA B  1 84  ? 21.74472 30.40691  -22.78333 1.000 19.79813 ? 115  ALA B C   1 
ATOM   4279 O  O   . ALA B  1 84  ? 21.83676 29.33505  -22.17032 1.000 17.64813 ? 115  ALA B O   1 
ATOM   4280 C  CB  . ALA B  1 84  ? 19.30285 30.19158  -23.26810 1.000 19.09386 ? 115  ALA B CB  1 
ATOM   4281 N  N   . TYR B  1 85  ? 22.77942 30.94047  -23.42720 1.000 18.89548 ? 116  TYR B N   1 
ATOM   4282 C  CA  . TYR B  1 85  ? 24.14467 30.47251  -23.24438 1.000 20.09971 ? 116  TYR B CA  1 
ATOM   4283 C  C   . TYR B  1 85  ? 24.98412 31.56268  -22.58308 1.000 16.72127 ? 116  TYR B C   1 
ATOM   4284 O  O   . TYR B  1 85  ? 24.72319 32.75634  -22.75260 1.000 18.47997 ? 116  TYR B O   1 
ATOM   4285 C  CB  . TYR B  1 85  ? 24.79220 30.09218  -24.58283 1.000 19.15892 ? 116  TYR B CB  1 
ATOM   4286 C  CG  . TYR B  1 85  ? 24.28632 28.82472  -25.23523 1.000 18.93584 ? 116  TYR B CG  1 
ATOM   4287 C  CD1 . TYR B  1 85  ? 24.86462 27.58962  -24.94386 1.000 17.04564 ? 116  TYR B CD1 1 
ATOM   4288 C  CD2 . TYR B  1 85  ? 23.25280 28.86296  -26.17202 1.000 19.77724 ? 116  TYR B CD2 1 
ATOM   4289 C  CE1 . TYR B  1 85  ? 24.41705 26.42044  -25.55535 1.000 19.01270 ? 116  TYR B CE1 1 
ATOM   4290 C  CE2 . TYR B  1 85  ? 22.79590 27.69260  -26.78258 1.000 21.36550 ? 116  TYR B CE2 1 
ATOM   4291 C  CZ  . TYR B  1 85  ? 23.39397 26.48050  -26.47667 1.000 19.85884 ? 116  TYR B CZ  1 
ATOM   4292 O  OH  . TYR B  1 85  ? 22.96768 25.32007  -27.07545 1.000 19.93440 ? 116  TYR B OH  1 
ATOM   4293 N  N   . ASN B  1 86  ? 26.00417 31.14686  -21.83091 1.000 17.47732 ? 117  ASN B N   1 
ATOM   4294 C  CA  . ASN B  1 86  ? 26.97258 32.09783  -21.29511 1.000 17.26897 ? 117  ASN B CA  1 
ATOM   4295 C  C   . ASN B  1 86  ? 27.75204 32.76590  -22.41719 1.000 20.11058 ? 117  ASN B C   1 
ATOM   4296 O  O   . ASN B  1 86  ? 28.06438 32.15119  -23.43940 1.000 21.28829 ? 117  ASN B O   1 
ATOM   4297 C  CB  . ASN B  1 86  ? 27.98892 31.40156  -20.38795 1.000 18.79860 ? 117  ASN B CB  1 
ATOM   4298 C  CG  . ASN B  1 86  ? 27.54946 31.33586  -18.95436 1.000 22.03147 ? 117  ASN B CG  1 
ATOM   4299 O  OD1 . ASN B  1 86  ? 26.48070 31.82528  -18.59596 1.000 19.00226 ? 117  ASN B OD1 1 
ATOM   4300 N  ND2 . ASN B  1 86  ? 28.36898 30.71483  -18.12328 1.000 20.87568 ? 117  ASN B ND2 1 
ATOM   4301 N  N   . LEU B  1 87  ? 28.09758 34.02740  -22.20409 1.000 19.65446 ? 118  LEU B N   1 
ATOM   4302 C  CA  . LEU B  1 87  ? 29.17000 34.61617  -22.99055 1.000 16.81128 ? 118  LEU B CA  1 
ATOM   4303 C  C   . LEU B  1 87  ? 30.47411 33.92013  -22.63382 1.000 20.16770 ? 118  LEU B C   1 
ATOM   4304 O  O   . LEU B  1 87  ? 30.69634 33.55183  -21.47836 1.000 22.04003 ? 118  LEU B O   1 
ATOM   4305 C  CB  . LEU B  1 87  ? 29.27296 36.11652  -22.71800 1.000 18.60674 ? 118  LEU B CB  1 
ATOM   4306 C  CG  . LEU B  1 87  ? 28.07898 36.95368  -23.16886 1.000 19.59430 ? 118  LEU B CG  1 
ATOM   4307 C  CD1 . LEU B  1 87  ? 28.09757 38.32754  -22.47590 1.000 20.38929 ? 118  LEU B CD1 1 
ATOM   4308 C  CD2 . LEU B  1 87  ? 28.09573 37.10074  -24.69117 1.000 20.74699 ? 118  LEU B CD2 1 
ATOM   4309 N  N   . PHE B  1 88  ? 31.32890 33.71614  -23.63515 1.000 23.24463 ? 119  PHE B N   1 
ATOM   4310 C  CA  . PHE B  1 88  ? 32.62722 33.10090  -23.39779 1.000 23.19765 ? 119  PHE B CA  1 
ATOM   4311 C  C   . PHE B  1 88  ? 33.53294 34.05845  -22.63077 1.000 23.82180 ? 119  PHE B C   1 
ATOM   4312 O  O   . PHE B  1 88  ? 33.30522 35.27135  -22.59162 1.000 23.22846 ? 119  PHE B O   1 
ATOM   4313 C  CB  . PHE B  1 88  ? 33.28777 32.71516  -24.72196 1.000 23.74073 ? 119  PHE B CB  1 
ATOM   4314 C  CG  . PHE B  1 88  ? 34.18826 31.51311  -24.62662 1.000 24.03792 ? 119  PHE B CG  1 
ATOM   4315 C  CD1 . PHE B  1 88  ? 33.65396 30.23453  -24.53897 1.000 26.32593 ? 119  PHE B CD1 1 
ATOM   4316 C  CD2 . PHE B  1 88  ? 35.56939 31.66101  -24.63338 1.000 25.38138 ? 119  PHE B CD2 1 
ATOM   4317 C  CE1 . PHE B  1 88  ? 34.48378 29.11815  -24.45935 1.000 26.07537 ? 119  PHE B CE1 1 
ATOM   4318 C  CE2 . PHE B  1 88  ? 36.40152 30.54967  -24.55427 1.000 28.87785 ? 119  PHE B CE2 1 
ATOM   4319 C  CZ  . PHE B  1 88  ? 35.86023 29.28296  -24.46507 1.000 26.50304 ? 119  PHE B CZ  1 
ATOM   4320 N  N   . HIS B  1 89  ? 34.57449 33.50547  -22.00957 1.000 23.44922 ? 120  HIS B N   1 
ATOM   4321 C  CA  . HIS B  1 89  ? 35.54202 34.37632  -21.36029 1.000 27.96033 ? 120  HIS B CA  1 
ATOM   4322 C  C   . HIS B  1 89  ? 36.15051 35.31109  -22.39695 1.000 26.02333 ? 120  HIS B C   1 
ATOM   4323 O  O   . HIS B  1 89  ? 36.31400 34.94329  -23.56471 1.000 24.01814 ? 120  HIS B O   1 
ATOM   4324 C  CB  . HIS B  1 89  ? 36.61953 33.56250  -20.63503 1.000 36.26037 ? 120  HIS B CB  1 
ATOM   4325 C  CG  . HIS B  1 89  ? 37.72505 33.05563  -21.50952 1.000 38.18630 ? 120  HIS B CG  1 
ATOM   4326 N  ND1 . HIS B  1 89  ? 38.78362 33.84564  -21.90770 1.000 42.26957 ? 120  HIS B ND1 1 
ATOM   4327 C  CD2 . HIS B  1 89  ? 37.97214 31.82017  -22.00891 1.000 46.23252 ? 120  HIS B CD2 1 
ATOM   4328 C  CE1 . HIS B  1 89  ? 39.61464 33.12850  -22.64434 1.000 44.38002 ? 120  HIS B CE1 1 
ATOM   4329 N  NE2 . HIS B  1 89  ? 39.14765 31.89474  -22.71847 1.000 43.07730 ? 120  HIS B NE2 1 
ATOM   4330 N  N   . ASN B  1 90  ? 36.40805 36.54927  -21.97979 1.000 24.78695 ? 121  ASN B N   1 
ATOM   4331 C  CA  . ASN B  1 90  ? 36.96674 37.57810  -22.86409 1.000 26.69481 ? 121  ASN B CA  1 
ATOM   4332 C  C   . ASN B  1 90  ? 36.11041 37.79375  -24.11509 1.000 27.57818 ? 121  ASN B C   1 
ATOM   4333 O  O   . ASN B  1 90  ? 36.62899 37.99987  -25.21732 1.000 27.80395 ? 121  ASN B O   1 
ATOM   4334 C  CB  . ASN B  1 90  ? 38.40876 37.22999  -23.24429 1.000 28.34766 ? 121  ASN B CB  1 
ATOM   4335 C  CG  . ASN B  1 90  ? 39.33710 37.20000  -22.04149 1.000 29.93828 ? 121  ASN B CG  1 
ATOM   4336 O  OD1 . ASN B  1 90  ? 39.21847 36.34500  -21.16148 1.000 32.57163 ? 121  ASN B OD1 1 
ATOM   4337 N  ND2 . ASN B  1 90  ? 40.27370 38.13557  -22.00168 1.000 35.38999 ? 121  ASN B ND2 1 
ATOM   4338 N  N   . SER B  1 91  ? 34.78705 37.74863  -23.95351 1.000 24.14748 ? 122  SER B N   1 
ATOM   4339 C  CA  . SER B  1 91  ? 33.89545 37.97026  -25.08688 1.000 24.33863 ? 122  SER B CA  1 
ATOM   4340 C  C   . SER B  1 91  ? 34.06052 39.38912  -25.63480 1.000 26.65994 ? 122  SER B C   1 
ATOM   4341 O  O   . SER B  1 91  ? 34.55074 40.29525  -24.95407 1.000 27.18367 ? 122  SER B O   1 
ATOM   4342 C  CB  . SER B  1 91  ? 32.43914 37.72176  -24.68673 1.000 24.58839 ? 122  SER B CB  1 
ATOM   4343 O  OG  . SER B  1 91  ? 32.00594 38.64714  -23.70762 1.000 23.96989 ? 122  SER B OG  1 
ATOM   4344 N  N   . SER B  1 92  ? 33.61095 39.57812  -26.87667 1.000 23.35304 ? 123  SER B N   1 
ATOM   4345 C  CA  . SER B  1 92  ? 33.97959 40.76486  -27.63946 1.000 25.86711 ? 123  SER B CA  1 
ATOM   4346 C  C   . SER B  1 92  ? 33.53867 42.04989  -26.95434 1.000 25.79225 ? 123  SER B C   1 
ATOM   4347 O  O   . SER B  1 92  ? 32.39258 42.18730  -26.50673 1.000 25.10681 ? 123  SER B O   1 
ATOM   4348 C  CB  . SER B  1 92  ? 33.38233 40.70749  -29.03945 1.000 28.02895 ? 123  SER B CB  1 
ATOM   4349 O  OG  . SER B  1 92  ? 33.64900 41.92473  -29.71598 1.000 28.47548 ? 123  SER B OG  1 
ATOM   4350 N  N   . GLU B  1 93  ? 34.45660 43.00595  -26.90255 1.000 26.77695 ? 124  GLU B N   1 
ATOM   4351 C  CA  . GLU B  1 93  ? 34.18970 44.31722  -26.33788 1.000 25.24119 ? 124  GLU B CA  1 
ATOM   4352 C  C   . GLU B  1 93  ? 33.84278 45.34205  -27.40806 1.000 26.11293 ? 124  GLU B C   1 
ATOM   4353 O  O   . GLU B  1 93  ? 33.81226 46.54058  -27.11765 1.000 27.48867 ? 124  GLU B O   1 
ATOM   4354 C  CB  . GLU B  1 93  ? 35.39190 44.75880  -25.50331 1.000 27.78357 ? 124  GLU B CB  1 
ATOM   4355 C  CG  . GLU B  1 93  ? 35.70736 43.72160  -24.42816 1.000 32.13297 ? 124  GLU B CG  1 
ATOM   4356 C  CD  . GLU B  1 93  ? 36.98756 43.97543  -23.66788 1.000 39.82068 ? 124  GLU B CD  1 
ATOM   4357 O  OE1 . GLU B  1 93  ? 37.66447 44.98804  -23.92959 1.000 38.69482 ? 124  GLU B OE1 1 
ATOM   4358 O  OE2 . GLU B  1 93  ? 37.31409 43.14706  -22.79398 1.000 40.22921 ? 124  GLU B OE2 1 
ATOM   4359 N  N   . ASP B  1 94  ? 33.56176 44.88994  -28.63088 1.000 25.93559 ? 125  ASP B N   1 
ATOM   4360 C  CA  . ASP B  1 94  ? 33.16775 45.75787  -29.73536 1.000 31.34592 ? 125  ASP B CA  1 
ATOM   4361 C  C   . ASP B  1 94  ? 31.65280 45.69729  -29.91693 1.000 29.66365 ? 125  ASP B C   1 
ATOM   4362 O  O   . ASP B  1 94  ? 31.09239 44.61106  -30.11399 1.000 28.91411 ? 125  ASP B O   1 
ATOM   4363 C  CB  . ASP B  1 94  ? 33.88690 45.33067  -31.01771 1.000 30.88970 ? 125  ASP B CB  1 
ATOM   4364 C  CG  . ASP B  1 94  ? 33.82913 46.38180  -32.10717 1.000 40.75089 ? 125  ASP B CG  1 
ATOM   4365 O  OD1 . ASP B  1 94  ? 32.73639 46.93559  -32.35303 1.000 46.29729 ? 125  ASP B OD1 1 
ATOM   4366 O  OD2 . ASP B  1 94  ? 34.88157 46.64721  -32.72727 1.000 52.31139 ? 125  ASP B OD2 1 
ATOM   4367 N  N   . ASP B  1 95  ? 30.99819 46.86579  -29.86167 1.000 27.10542 ? 126  ASP B N   1 
ATOM   4368 C  CA  . ASP B  1 95  ? 29.55250 46.94652  -30.07450 1.000 29.87431 ? 126  ASP B CA  1 
ATOM   4369 C  C   . ASP B  1 95  ? 29.10940 46.19789  -31.32386 1.000 30.80207 ? 126  ASP B C   1 
ATOM   4370 O  O   . ASP B  1 95  ? 28.02643 45.60021  -31.33630 1.000 31.18587 ? 126  ASP B O   1 
ATOM   4371 C  CB  . ASP B  1 95  ? 29.09895 48.40894  -30.19180 1.000 29.20629 ? 126  ASP B CB  1 
ATOM   4372 C  CG  . ASP B  1 95  ? 28.96781 49.11518  -28.84268 1.000 31.17261 ? 126  ASP B CG  1 
ATOM   4373 O  OD1 . ASP B  1 95  ? 29.16082 48.48347  -27.78266 1.000 30.39905 ? 126  ASP B OD1 1 
ATOM   4374 O  OD2 . ASP B  1 95  ? 28.67140 50.32865  -28.84875 1.000 31.10063 ? 126  ASP B OD2 1 
ATOM   4375 N  N   . LYS B  1 96  ? 29.93632 46.20610  -32.37795 1.000 31.43491 ? 127  LYS B N   1 
ATOM   4376 C  CA  . LYS B  1 96  ? 29.53390 45.62182  -33.65566 1.000 33.14290 ? 127  LYS B CA  1 
ATOM   4377 C  C   . LYS B  1 96  ? 29.24840 44.12939  -33.53898 1.000 29.81315 ? 127  LYS B C   1 
ATOM   4378 O  O   . LYS B  1 96  ? 28.47699 43.58150  -34.33311 1.000 31.27328 ? 127  LYS B O   1 
ATOM   4379 C  CB  . LYS B  1 96  ? 30.61972 45.86145  -34.71269 1.000 35.90021 ? 127  LYS B CB  1 
ATOM   4380 C  CG  . LYS B  1 96  ? 31.80836 44.91826  -34.59535 1.000 38.36464 ? 127  LYS B CG  1 
ATOM   4381 C  CD  . LYS B  1 96  ? 32.92765 45.25431  -35.57360 1.000 46.73082 ? 127  LYS B CD  1 
ATOM   4382 C  CE  . LYS B  1 96  ? 32.46904 45.11960  -37.01612 1.000 52.36629 ? 127  LYS B CE  1 
ATOM   4383 N  NZ  . LYS B  1 96  ? 33.59925 45.27140  -37.98488 1.000 57.96935 ? 127  LYS B NZ  1 
ATOM   4384 N  N   . ASP B  1 97  ? 29.85607 43.45600  -32.56460 1.000 31.74042 ? 128  ASP B N   1 
ATOM   4385 C  CA  . ASP B  1 97  ? 29.71224 42.01371  -32.42180 1.000 26.37260 ? 128  ASP B CA  1 
ATOM   4386 C  C   . ASP B  1 97  ? 28.49470 41.60648  -31.60084 1.000 31.50162 ? 128  ASP B C   1 
ATOM   4387 O  O   . ASP B  1 97  ? 28.14219 40.42199  -31.60234 1.000 30.19725 ? 128  ASP B O   1 
ATOM   4388 C  CB  . ASP B  1 97  ? 30.98078 41.43085  -31.79699 1.000 26.76823 ? 128  ASP B CB  1 
ATOM   4389 C  CG  . ASP B  1 97  ? 32.18779 41.57906  -32.70068 1.000 31.09174 ? 128  ASP B CG  1 
ATOM   4390 O  OD1 . ASP B  1 97  ? 32.01148 41.48849  -33.93518 1.000 36.43905 ? 128  ASP B OD1 1 
ATOM   4391 O  OD2 . ASP B  1 97  ? 33.30148 41.78119  -32.18064 1.000 31.12263 ? 128  ASP B OD2 1 
ATOM   4392 N  N   . ASN B  1 98  ? 27.85546 42.55074  -30.90358 1.000 28.31737 ? 129  ASN B N   1 
ATOM   4393 C  CA  . ASN B  1 98  ? 26.57012 42.31654  -30.23620 1.000 28.38240 ? 129  ASN B CA  1 
ATOM   4394 C  C   . ASN B  1 98  ? 26.61890 41.13470  -29.26817 1.000 26.45159 ? 129  ASN B C   1 
ATOM   4395 O  O   . ASN B  1 98  ? 25.66373 40.35824  -29.15279 1.000 26.92219 ? 129  ASN B O   1 
ATOM   4396 C  CB  . ASN B  1 98  ? 25.45822 42.12537  -31.26226 1.000 29.24742 ? 129  ASN B CB  1 
ATOM   4397 C  CG  . ASN B  1 98  ? 24.96619 43.43656  -31.82112 1.000 37.90790 ? 129  ASN B CG  1 
ATOM   4398 O  OD1 . ASN B  1 98  ? 24.78252 44.39947  -31.08112 1.000 40.59151 ? 129  ASN B OD1 1 
ATOM   4399 N  ND2 . ASN B  1 98  ? 24.76314 43.49034  -33.12982 1.000 39.71910 ? 129  ASN B ND2 1 
ATOM   4400 N  N   . MET B  1 99  ? 27.73156 41.01173  -28.54475 1.000 24.18772 ? 130  MET B N   1 
ATOM   4401 C  CA  . MET B  1 99  ? 27.90548 39.93389  -27.56096 1.000 23.08738 ? 130  MET B CA  1 
ATOM   4402 C  C   . MET B  1 99  ? 27.45585 40.44908  -26.19838 1.000 19.53094 ? 130  MET B C   1 
ATOM   4403 O  O   . MET B  1 99  ? 28.25613 40.82612  -25.33718 1.000 19.91284 ? 130  MET B O   1 
ATOM   4404 C  CB  . MET B  1 99  ? 29.35089 39.45542  -27.54101 1.000 23.87534 ? 130  MET B CB  1 
ATOM   4405 C  CG  . MET B  1 99  ? 29.72158 38.59940  -28.73484 1.000 28.41084 ? 130  MET B CG  1 
ATOM   4406 S  SD  . MET B  1 99  ? 28.97395 36.96382  -28.61422 1.000 28.82447 ? 130  MET B SD  1 
ATOM   4407 C  CE  . MET B  1 99  ? 29.68448 36.17756  -30.05672 1.000 28.53284 ? 130  MET B CE  1 
ATOM   4408 N  N   . GLY B  1 100 ? 26.14196 40.48116  -26.01914 1.000 22.79062 ? 131  GLY B N   1 
ATOM   4409 C  CA  . GLY B  1 100 ? 25.55522 41.02933  -24.80595 1.000 21.32001 ? 131  GLY B CA  1 
ATOM   4410 C  C   . GLY B  1 100 ? 24.04705 40.97014  -24.89995 1.000 20.51621 ? 131  GLY B C   1 
ATOM   4411 O  O   . GLY B  1 100 ? 23.47284 40.73574  -25.96885 1.000 21.66871 ? 131  GLY B O   1 
ATOM   4412 N  N   . VAL B  1 101 ? 23.40784 41.17924  -23.75231 1.000 19.09734 ? 132  VAL B N   1 
ATOM   4413 C  CA  . VAL B  1 101 ? 21.94558 41.08841  -23.70968 1.000 19.44198 ? 132  VAL B CA  1 
ATOM   4414 C  C   . VAL B  1 101 ? 21.35195 42.18941  -24.58043 1.000 20.85911 ? 132  VAL B C   1 
ATOM   4415 O  O   . VAL B  1 101 ? 21.79087 43.35111  -24.48165 1.000 21.79984 ? 132  VAL B O   1 
ATOM   4416 C  CB  . VAL B  1 101 ? 21.44344 41.19988  -22.26098 1.000 20.90666 ? 132  VAL B CB  1 
ATOM   4417 C  CG1 . VAL B  1 101 ? 19.91805 41.16462  -22.21953 1.000 20.57265 ? 132  VAL B CG1 1 
ATOM   4418 C  CG2 . VAL B  1 101 ? 22.03121 40.06797  -21.42212 1.000 21.53302 ? 132  VAL B CG2 1 
ATOM   4419 N  N   . PRO B  1 102 ? 20.37918 41.87843  -25.46593 1.000 22.52159 ? 133  PRO B N   1 
ATOM   4420 C  CA  . PRO B  1 102 ? 19.80818 42.90301  -26.35913 1.000 22.42404 ? 133  PRO B CA  1 
ATOM   4421 C  C   . PRO B  1 102 ? 19.49581 44.22812  -25.68009 1.000 24.37503 ? 133  PRO B C   1 
ATOM   4422 O  O   . PRO B  1 102 ? 18.82223 44.25729  -24.64567 1.000 22.18538 ? 133  PRO B O   1 
ATOM   4423 C  CB  . PRO B  1 102 ? 18.52911 42.22826  -26.86869 1.000 25.08637 ? 133  PRO B CB  1 
ATOM   4424 C  CG  . PRO B  1 102 ? 18.87992 40.78272  -26.91559 1.000 24.93088 ? 133  PRO B CG  1 
ATOM   4425 C  CD  . PRO B  1 102 ? 19.81845 40.54238  -25.73774 1.000 22.68404 ? 133  PRO B CD  1 
ATOM   4426 N  N   . VAL B  1 103 ? 19.99384 45.33135  -26.25272 1.000 24.56262 ? 134  VAL B N   1 
ATOM   4427 C  CA  . VAL B  1 103 ? 19.80958 46.63907  -25.63319 1.000 23.37398 ? 134  VAL B CA  1 
ATOM   4428 C  C   . VAL B  1 103 ? 18.35121 47.06597  -25.63910 1.000 23.08657 ? 134  VAL B C   1 
ATOM   4429 O  O   . VAL B  1 103 ? 17.95937 47.90869  -24.82537 1.000 27.82868 ? 134  VAL B O   1 
ATOM   4430 C  CB  . VAL B  1 103 ? 20.68772 47.70321  -26.32523 1.000 23.09822 ? 134  VAL B CB  1 
ATOM   4431 C  CG1 . VAL B  1 103 ? 22.16117 47.41493  -26.09409 1.000 25.19041 ? 134  VAL B CG1 1 
ATOM   4432 C  CG2 . VAL B  1 103 ? 20.37260 47.76066  -27.81450 1.000 29.07632 ? 134  VAL B CG2 1 
ATOM   4433 N  N   . GLU B  1 104 ? 17.52392 46.47992  -26.51144 1.000 24.74179 ? 135  GLU B N   1 
ATOM   4434 C  CA  . GLU B  1 104 ? 16.10658 46.82555  -26.54927 1.000 25.82518 ? 135  GLU B CA  1 
ATOM   4435 C  C   . GLU B  1 104 ? 15.33410 46.23351  -25.37806 1.000 27.28922 ? 135  GLU B C   1 
ATOM   4436 O  O   . GLU B  1 104 ? 14.21732 46.68322  -25.09095 1.000 25.19229 ? 135  GLU B O   1 
ATOM   4437 C  CB  . GLU B  1 104 ? 15.48579 46.35270  -27.86610 1.000 31.92590 ? 135  GLU B CB  1 
ATOM   4438 C  CG  . GLU B  1 104 ? 16.14810 46.91463  -29.12515 1.000 38.77638 ? 135  GLU B CG  1 
ATOM   4439 C  CD  . GLU B  1 104 ? 17.38621 46.13160  -29.56660 1.000 44.54862 ? 135  GLU B CD  1 
ATOM   4440 O  OE1 . GLU B  1 104 ? 17.78902 45.17581  -28.86412 1.000 37.60681 ? 135  GLU B OE1 1 
ATOM   4441 O  OE2 . GLU B  1 104 ? 17.95771 46.47799  -30.62640 1.000 47.14999 ? 135  GLU B OE2 1 
ATOM   4442 N  N   . GLU B  1 105 ? 15.89671 45.23402  -24.69940 1.000 24.50478 ? 136  GLU B N   1 
ATOM   4443 C  CA  . GLU B  1 105 ? 15.19835 44.55194  -23.60985 1.000 21.63637 ? 136  GLU B CA  1 
ATOM   4444 C  C   . GLU B  1 105 ? 15.48589 45.30529  -22.31771 1.000 21.98152 ? 136  GLU B C   1 
ATOM   4445 O  O   . GLU B  1 105 ? 16.43004 44.98983  -21.59445 1.000 25.53927 ? 136  GLU B O   1 
ATOM   4446 C  CB  . GLU B  1 105 ? 15.64662 43.09862  -23.53017 1.000 21.43938 ? 136  GLU B CB  1 
ATOM   4447 C  CG  . GLU B  1 105 ? 14.74728 42.24019  -22.69393 1.000 25.23306 ? 136  GLU B CG  1 
ATOM   4448 C  CD  . GLU B  1 105 ? 13.35866 42.16569  -23.27259 1.000 24.32284 ? 136  GLU B CD  1 
ATOM   4449 O  OE1 . GLU B  1 105 ? 13.19891 41.58029  -24.36122 1.000 25.06182 ? 136  GLU B OE1 1 
ATOM   4450 O  OE2 . GLU B  1 105 ? 12.42973 42.71310  -22.64652 1.000 26.28259 ? 136  GLU B OE2 1 
ATOM   4451 N  N   . THR B  1 106 ? 14.63896 46.29701  -22.00779 1.000 20.31913 ? 137  THR B N   1 
ATOM   4452 C  CA  . THR B  1 106 ? 14.92622 47.25625  -20.94378 1.000 19.87768 ? 137  THR B CA  1 
ATOM   4453 C  C   . THR B  1 106 ? 15.08123 46.58502  -19.58103 1.000 20.11222 ? 137  THR B C   1 
ATOM   4454 O  O   . THR B  1 106 ? 14.20586 45.83431  -19.13540 1.000 21.79856 ? 137  THR B O   1 
ATOM   4455 C  CB  . THR B  1 106 ? 13.81386 48.30149  -20.87935 1.000 23.18670 ? 137  THR B CB  1 
ATOM   4456 O  OG1 . THR B  1 106 ? 13.59768 48.83402  -22.19037 1.000 25.82402 ? 137  THR B OG1 1 
ATOM   4457 C  CG2 . THR B  1 106 ? 14.19886 49.43256  -19.94733 1.000 21.49886 ? 137  THR B CG2 1 
ATOM   4458 N  N   . TYR B  1 107 ? 16.18795 46.89625  -18.90798 1.000 20.07688 ? 138  TYR B N   1 
ATOM   4459 C  CA  . TYR B  1 107 ? 16.46000 46.38267  -17.56798 1.000 19.12094 ? 138  TYR B CA  1 
ATOM   4460 C  C   . TYR B  1 107 ? 15.62539 47.09056  -16.50511 1.000 20.94802 ? 138  TYR B C   1 
ATOM   4461 O  O   . TYR B  1 107 ? 15.30770 48.28276  -16.61570 1.000 19.60985 ? 138  TYR B O   1 
ATOM   4462 C  CB  . TYR B  1 107 ? 17.92981 46.56667  -17.20619 1.000 18.35618 ? 138  TYR B CB  1 
ATOM   4463 C  CG  . TYR B  1 107 ? 18.90919 45.65029  -17.89715 1.000 19.13810 ? 138  TYR B CG  1 
ATOM   4464 C  CD1 . TYR B  1 107 ? 18.50457 44.75630  -18.88831 1.000 18.97444 ? 138  TYR B CD1 1 
ATOM   4465 C  CD2 . TYR B  1 107 ? 20.24914 45.68184  -17.54415 1.000 19.85383 ? 138  TYR B CD2 1 
ATOM   4466 C  CE1 . TYR B  1 107 ? 19.42869 43.92207  -19.51609 1.000 20.07517 ? 138  TYR B CE1 1 
ATOM   4467 C  CE2 . TYR B  1 107 ? 21.17434 44.85304  -18.14802 1.000 17.60004 ? 138  TYR B CE2 1 
ATOM   4468 C  CZ  . TYR B  1 107 ? 20.76234 43.97714  -19.13257 1.000 20.18691 ? 138  TYR B CZ  1 
ATOM   4469 O  OH  . TYR B  1 107 ? 21.70101 43.16397  -19.73383 1.000 18.85776 ? 138  TYR B OH  1 
ATOM   4470 N  N   . MET B  1 108 ? 15.31399 46.35557  -15.42733 1.000 18.45667 ? 139  MET B N   1 
ATOM   4471 C  CA  . MET B  1 108 ? 14.57532 47.00026  -14.34791 1.000 18.91317 ? 139  MET B CA  1 
ATOM   4472 C  C   . MET B  1 108 ? 15.37919 48.12014  -13.71066 1.000 20.27584 ? 139  MET B C   1 
ATOM   4473 O  O   . MET B  1 108 ? 14.78466 49.04638  -13.15699 1.000 18.88880 ? 139  MET B O   1 
ATOM   4474 C  CB  . MET B  1 108 ? 14.14272 45.99109  -13.28284 1.000 19.79329 ? 139  MET B CB  1 
ATOM   4475 C  CG  . MET B  1 108 ? 15.27339 45.16648  -12.67379 1.000 20.29348 ? 139  MET B CG  1 
ATOM   4476 S  SD  . MET B  1 108 ? 14.64429 44.30627  -11.20837 1.000 22.43026 ? 139  MET B SD  1 
ATOM   4477 C  CE  . MET B  1 108 ? 15.97696 43.15648  -10.88265 1.000 22.12580 ? 139  MET B CE  1 
ATOM   4478 N  N   . SER B  1 109 ? 16.71197 48.07402  -13.80503 1.000 19.62186 ? 140  SER B N   1 
ATOM   4479 C  CA  . SER B  1 109 ? 17.53390 49.17725  -13.31025 1.000 18.46228 ? 140  SER B CA  1 
ATOM   4480 C  C   . SER B  1 109 ? 17.17951 50.48519  -14.01198 1.000 20.54180 ? 140  SER B C   1 
ATOM   4481 O  O   . SER B  1 109 ? 17.01599 51.52593  -13.36466 1.000 21.12565 ? 140  SER B O   1 
ATOM   4482 C  CB  . SER B  1 109 ? 19.01448 48.84130  -13.50219 1.000 19.75710 ? 140  SER B CB  1 
ATOM   4483 O  OG  . SER B  1 109 ? 19.22207 48.27052  -14.78002 1.000 20.31211 ? 140  SER B OG  1 
ATOM   4484 N  N   . LYS B  1 110 ? 17.04155 50.44559  -15.34116 1.000 20.11986 ? 141  LYS B N   1 
ATOM   4485 C  CA  . LYS B  1 110 ? 16.68431 51.65503  -16.07777 1.000 20.88176 ? 141  LYS B CA  1 
ATOM   4486 C  C   . LYS B  1 110 ? 15.26822 52.11318  -15.73597 1.000 24.32423 ? 141  LYS B C   1 
ATOM   4487 O  O   . LYS B  1 110 ? 15.02199 53.31409  -15.58658 1.000 21.74499 ? 141  LYS B O   1 
ATOM   4488 C  CB  . LYS B  1 110 ? 16.83970 51.42173  -17.58258 1.000 22.13287 ? 141  LYS B CB  1 
ATOM   4489 C  CG  . LYS B  1 110 ? 16.55132 52.66788  -18.43337 1.000 26.42665 ? 141  LYS B CG  1 
ATOM   4490 C  CD  . LYS B  1 110 ? 17.10411 52.51721  -19.83650 1.000 35.48975 ? 141  LYS B CD  1 
ATOM   4491 C  CE  . LYS B  1 110 ? 18.62722 52.60651  -19.83731 1.000 36.48677 ? 141  LYS B CE  1 
ATOM   4492 N  NZ  . LYS B  1 110 ? 19.20178 52.31661  -21.18777 1.000 38.94704 ? 141  LYS B NZ  1 
ATOM   4493 N  N   . VAL B  1 111 ? 14.32569 51.17622  -15.59220 1.000 21.01859 ? 142  VAL B N   1 
ATOM   4494 C  CA  . VAL B  1 111 ? 12.96520 51.56281  -15.21544 1.000 19.57566 ? 142  VAL B CA  1 
ATOM   4495 C  C   . VAL B  1 111 ? 12.96920 52.27098  -13.86671 1.000 23.58138 ? 142  VAL B C   1 
ATOM   4496 O  O   . VAL B  1 111 ? 12.30841 53.30585  -13.68175 1.000 20.91402 ? 142  VAL B O   1 
ATOM   4497 C  CB  . VAL B  1 111 ? 12.04263 50.32892  -15.20577 1.000 20.18865 ? 142  VAL B CB  1 
ATOM   4498 C  CG1 . VAL B  1 111 ? 10.64660 50.71662  -14.73647 1.000 21.57023 ? 142  VAL B CG1 1 
ATOM   4499 C  CG2 . VAL B  1 111 ? 11.99064 49.68620  -16.59034 1.000 22.73641 ? 142  VAL B CG2 1 
ATOM   4500 N  N   . LEU B  1 112 ? 13.71273 51.72547  -12.90313 1.000 20.53518 ? 143  LEU B N   1 
ATOM   4501 C  CA  . LEU B  1 112 ? 13.79272 52.33818  -11.58207 1.000 19.79437 ? 143  LEU B CA  1 
ATOM   4502 C  C   . LEU B  1 112 ? 14.50761 53.68102  -11.64080 1.000 21.50982 ? 143  LEU B C   1 
ATOM   4503 O  O   . LEU B  1 112 ? 14.10162 54.64000  -10.97093 1.000 21.68575 ? 143  LEU B O   1 
ATOM   4504 C  CB  . LEU B  1 112 ? 14.51357 51.39830  -10.62059 1.000 21.21161 ? 143  LEU B CB  1 
ATOM   4505 C  CG  . LEU B  1 112 ? 13.78354 50.08666  -10.35534 1.000 23.74112 ? 143  LEU B CG  1 
ATOM   4506 C  CD1 . LEU B  1 112 ? 14.66649 49.11875  -9.59151  1.000 22.12298 ? 143  LEU B CD1 1 
ATOM   4507 C  CD2 . LEU B  1 112 ? 12.55157 50.37878  -9.56738  1.000 25.91990 ? 143  LEU B CD2 1 
ATOM   4508 N  N   . GLN B  1 113 ? 15.59167 53.75336  -12.41577 1.000 20.76714 ? 144  GLN B N   1 
ATOM   4509 C  CA  . GLN B  1 113 ? 16.31533 55.00912  -12.58210 1.000 21.78697 ? 144  GLN B CA  1 
ATOM   4510 C  C   . GLN B  1 113 ? 15.39876 56.08555  -13.14554 1.000 24.38280 ? 144  GLN B C   1 
ATOM   4511 O  O   . GLN B  1 113 ? 15.36028 57.21341  -12.63968 1.000 24.52067 ? 144  GLN B O   1 
ATOM   4512 C  CB  . GLN B  1 113 ? 17.52014 54.78227  -13.49376 1.000 21.99095 ? 144  GLN B CB  1 
ATOM   4513 C  CG  . GLN B  1 113 ? 18.46742 55.96482  -13.63874 1.000 24.46606 ? 144  GLN B CG  1 
ATOM   4514 C  CD  . GLN B  1 113 ? 19.48123 55.72251  -14.74463 1.000 24.95453 ? 144  GLN B CD  1 
ATOM   4515 O  OE1 . GLN B  1 113 ? 19.11557 55.35660  -15.85952 1.000 25.73688 ? 144  GLN B OE1 1 
ATOM   4516 N  NE2 . GLN B  1 113 ? 20.75418 55.89565  -14.43304 1.000 24.75745 ? 144  GLN B NE2 1 
ATOM   4517 N  N   . ASN B  1 114 ? 14.62258 55.73679  -14.17892 1.000 23.31459 ? 145  ASN B N   1 
ATOM   4518 C  CA  . ASN B  1 114 ? 13.66736 56.67654  -14.75551 1.000 24.49021 ? 145  ASN B CA  1 
ATOM   4519 C  C   . ASN B  1 114 ? 12.57142 57.06921  -13.77648 1.000 27.11976 ? 145  ASN B C   1 
ATOM   4520 O  O   . ASN B  1 114 ? 11.95821 58.12984  -13.94858 1.000 27.78456 ? 145  ASN B O   1 
ATOM   4521 C  CB  . ASN B  1 114 ? 13.03907 56.08431  -16.01519 1.000 24.71130 ? 145  ASN B CB  1 
ATOM   4522 C  CG  . ASN B  1 114 ? 14.00853 56.02208  -17.17383 1.000 30.11929 ? 145  ASN B CG  1 
ATOM   4523 O  OD1 . ASN B  1 114 ? 15.03388 56.70317  -17.17940 1.000 39.64645 ? 145  ASN B OD1 1 
ATOM   4524 N  ND2 . ASN B  1 114 ? 13.68435 55.20714  -18.17054 1.000 38.32234 ? 145  ASN B ND2 1 
ATOM   4525 N  N   . ALA B  1 115 ? 12.31426 56.24705  -12.75950 1.000 23.65877 ? 146  ALA B N   1 
ATOM   4526 C  CA  . ALA B  1 115 ? 11.33160 56.53180  -11.72585 1.000 22.39114 ? 146  ALA B CA  1 
ATOM   4527 C  C   . ALA B  1 115 ? 11.91687 57.30707  -10.56223 1.000 23.20701 ? 146  ALA B C   1 
ATOM   4528 O  O   . ALA B  1 115 ? 11.22978 57.49942  -9.55585  1.000 23.74881 ? 146  ALA B O   1 
ATOM   4529 C  CB  . ALA B  1 115 ? 10.71146 55.23203  -11.20607 1.000 21.85602 ? 146  ALA B CB  1 
ATOM   4530 N  N   . GLY B  1 116 ? 13.16336 57.75353  -10.67148 1.000 23.17348 ? 147  GLY B N   1 
ATOM   4531 C  CA  . GLY B  1 116 ? 13.76485 58.57031  -9.64132  1.000 20.70649 ? 147  GLY B CA  1 
ATOM   4532 C  C   . GLY B  1 116 ? 14.61003 57.83827  -8.62205  1.000 21.95599 ? 147  GLY B C   1 
ATOM   4533 O  O   . GLY B  1 116 ? 15.01235 58.45221  -7.62870  1.000 22.90968 ? 147  GLY B O   1 
ATOM   4534 N  N   . TYR B  1 117 ? 14.87633 56.54862  -8.81754  1.000 21.58032 ? 148  TYR B N   1 
ATOM   4535 C  CA  . TYR B  1 117 ? 15.77348 55.82485  -7.92727  1.000 19.17516 ? 148  TYR B CA  1 
ATOM   4536 C  C   . TYR B  1 117 ? 17.22950 56.13888  -8.24349  1.000 20.76279 ? 148  TYR B C   1 
ATOM   4537 O  O   . TYR B  1 117 ? 17.60165 56.31630  -9.40619  1.000 21.39655 ? 148  TYR B O   1 
ATOM   4538 C  CB  . TYR B  1 117 ? 15.54070 54.31496  -8.04705  1.000 18.82123 ? 148  TYR B CB  1 
ATOM   4539 C  CG  . TYR B  1 117 ? 14.44092 53.79446  -7.15270  1.000 18.91525 ? 148  TYR B CG  1 
ATOM   4540 C  CD1 . TYR B  1 117 ? 13.13022 54.24701  -7.29332  1.000 21.26797 ? 148  TYR B CD1 1 
ATOM   4541 C  CD2 . TYR B  1 117 ? 14.71712 52.87288  -6.15200  1.000 20.40660 ? 148  TYR B CD2 1 
ATOM   4542 C  CE1 . TYR B  1 117 ? 12.12576 53.78309  -6.47317  1.000 19.11513 ? 148  TYR B CE1 1 
ATOM   4543 C  CE2 . TYR B  1 117 ? 13.71501 52.37836  -5.34177  1.000 18.97093 ? 148  TYR B CE2 1 
ATOM   4544 C  CZ  . TYR B  1 117 ? 12.41745 52.84526  -5.49986  1.000 18.95422 ? 148  TYR B CZ  1 
ATOM   4545 O  OH  . TYR B  1 117 ? 11.42175 52.37872  -4.67237  1.000 20.74877 ? 148  TYR B OH  1 
ATOM   4546 N  N   . TYR B  1 118 ? 18.05390 56.19196  -7.19692  1.000 20.25669 ? 149  TYR B N   1 
ATOM   4547 C  CA  . TYR B  1 118 ? 19.50396 56.17188  -7.36529  1.000 20.19231 ? 149  TYR B CA  1 
ATOM   4548 C  C   . TYR B  1 118 ? 19.93572 54.72020  -7.52279  1.000 20.62073 ? 149  TYR B C   1 
ATOM   4549 O  O   . TYR B  1 118 ? 19.64020 53.89157  -6.65858  1.000 20.08393 ? 149  TYR B O   1 
ATOM   4550 C  CB  . TYR B  1 118 ? 20.20310 56.81294  -6.16849  1.000 21.40942 ? 149  TYR B CB  1 
ATOM   4551 C  CG  . TYR B  1 118 ? 21.69726 56.62202  -6.20554  1.000 20.47868 ? 149  TYR B CG  1 
ATOM   4552 C  CD1 . TYR B  1 118 ? 22.48553 57.39186  -7.04472  1.000 25.07041 ? 149  TYR B CD1 1 
ATOM   4553 C  CD2 . TYR B  1 118 ? 22.31760 55.66264  -5.41253  1.000 25.20530 ? 149  TYR B CD2 1 
ATOM   4554 C  CE1 . TYR B  1 118 ? 23.85213 57.22267  -7.09109  1.000 26.83853 ? 149  TYR B CE1 1 
ATOM   4555 C  CE2 . TYR B  1 118 ? 23.68343 55.48159  -5.45617  1.000 25.56620 ? 149  TYR B CE2 1 
ATOM   4556 C  CZ  . TYR B  1 118 ? 24.44240 56.25969  -6.29561  1.000 23.89038 ? 149  TYR B CZ  1 
ATOM   4557 O  OH  . TYR B  1 118 ? 25.81413 56.08338  -6.34262  1.000 25.97237 ? 149  TYR B OH  1 
ATOM   4558 N  N   . THR B  1 119 ? 20.60595 54.40107  -8.62602  1.000 19.63615 ? 150  THR B N   1 
ATOM   4559 C  CA  . THR B  1 119 ? 20.86461 53.01171  -8.99288  1.000 19.13931 ? 150  THR B CA  1 
ATOM   4560 C  C   . THR B  1 119 ? 22.35825 52.70978  -8.98986  1.000 23.23665 ? 150  THR B C   1 
ATOM   4561 O  O   . THR B  1 119 ? 23.17338 53.52101  -9.44305  1.000 21.68448 ? 150  THR B O   1 
ATOM   4562 C  CB  . THR B  1 119 ? 20.26567 52.68920  -10.36685 1.000 21.47319 ? 150  THR B CB  1 
ATOM   4563 O  OG1 . THR B  1 119 ? 20.74969 53.63515  -11.32765 1.000 22.28421 ? 150  THR B OG1 1 
ATOM   4564 C  CG2 . THR B  1 119 ? 18.74173 52.77282  -10.31391 1.000 20.54879 ? 150  THR B CG2 1 
ATOM   4565 N  N   . SER B  1 120 ? 22.70921 51.52608  -8.48277  1.000 19.35017 ? 151  SER B N   1 
ATOM   4566 C  CA  . SER B  1 120 ? 24.10095 51.13766  -8.29466  1.000 18.69773 ? 151  SER B CA  1 
ATOM   4567 C  C   . SER B  1 120 ? 24.22770 49.64738  -8.56013  1.000 19.93499 ? 151  SER B C   1 
ATOM   4568 O  O   . SER B  1 120 ? 23.40943 48.86587  -8.06784  1.000 19.94000 ? 151  SER B O   1 
ATOM   4569 C  CB  . SER B  1 120 ? 24.56047 51.45938  -6.86742  1.000 20.72022 ? 151  SER B CB  1 
ATOM   4570 O  OG  . SER B  1 120 ? 25.64743 50.63903  -6.46188  1.000 25.98746 ? 151  SER B OG  1 
ATOM   4571 N  N   . ALA B  1 121 ? 25.24374 49.26158  -9.33700  1.000 17.94299 ? 152  ALA B N   1 
ATOM   4572 C  CA  . ALA B  1 121 ? 25.58804 47.86433  -9.57225  1.000 18.50995 ? 152  ALA B CA  1 
ATOM   4573 C  C   . ALA B  1 121 ? 27.00289 47.63075  -9.07449  1.000 18.16928 ? 152  ALA B C   1 
ATOM   4574 O  O   . ALA B  1 121 ? 27.89528 48.45123  -9.31001  1.000 19.12569 ? 152  ALA B O   1 
ATOM   4575 C  CB  . ALA B  1 121 ? 25.48969 47.49141  -11.06298 1.000 17.57350 ? 152  ALA B CB  1 
ATOM   4576 N  N   . ILE B  1 122 ? 27.20020 46.52657  -8.36172  1.000 17.68737 ? 153  ILE B N   1 
ATOM   4577 C  CA  . ILE B  1 122 ? 28.47798 46.23545  -7.72492  1.000 17.71367 ? 153  ILE B CA  1 
ATOM   4578 C  C   . ILE B  1 122 ? 28.81196 44.77801  -7.98612  1.000 18.75957 ? 153  ILE B C   1 
ATOM   4579 O  O   . ILE B  1 122 ? 27.94680 43.90618  -7.84169  1.000 20.76786 ? 153  ILE B O   1 
ATOM   4580 C  CB  . ILE B  1 122 ? 28.44203 46.50454  -6.20949  1.000 16.73554 ? 153  ILE B CB  1 
ATOM   4581 C  CG1 . ILE B  1 122 ? 28.10707 47.96838  -5.92286  1.000 18.07124 ? 153  ILE B CG1 1 
ATOM   4582 C  CG2 . ILE B  1 122 ? 29.77210 46.12572  -5.56224  1.000 17.91204 ? 153  ILE B CG2 1 
ATOM   4583 C  CD1 . ILE B  1 122 ? 27.71247 48.21970  -4.49958  1.000 20.25999 ? 153  ILE B CD1 1 
ATOM   4584 N  N   . GLY B  1 123 ? 30.04872 44.51483  -8.39259  1.000 18.55158 ? 154  GLY B N   1 
ATOM   4585 C  CA  . GLY B  1 123 ? 30.54158 43.15046  -8.50451  1.000 18.10590 ? 154  GLY B CA  1 
ATOM   4586 C  C   . GLY B  1 123 ? 30.44445 42.61291  -9.92638  1.000 18.84152 ? 154  GLY B C   1 
ATOM   4587 O  O   . GLY B  1 123 ? 30.88478 43.26048  -10.87443 1.000 18.99265 ? 154  GLY B O   1 
ATOM   4588 N  N   . LYS B  1 124 ? 29.87881 41.41013  -10.06421 1.000 18.48434 ? 155  LYS B N   1 
ATOM   4589 C  CA  . LYS B  1 124 ? 29.86203 40.68959  -11.33318 1.000 16.56608 ? 155  LYS B CA  1 
ATOM   4590 C  C   . LYS B  1 124 ? 28.74718 41.18323  -12.25200 1.000 19.69081 ? 155  LYS B C   1 
ATOM   4591 O  O   . LYS B  1 124 ? 27.62315 41.42477  -11.80966 1.000 20.29300 ? 155  LYS B O   1 
ATOM   4592 C  CB  . LYS B  1 124 ? 29.68314 39.19549  -11.05419 1.000 17.48076 ? 155  LYS B CB  1 
ATOM   4593 C  CG  . LYS B  1 124 ? 29.35393 38.33094  -12.25825 1.000 18.72354 ? 155  LYS B CG  1 
ATOM   4594 C  CD  . LYS B  1 124 ? 29.51698 36.84969  -11.89502 1.000 17.78739 ? 155  LYS B CD  1 
ATOM   4595 C  CE  . LYS B  1 124 ? 28.97649 35.92857  -12.99360 1.000 19.30463 ? 155  LYS B CE  1 
ATOM   4596 N  NZ  . LYS B  1 124 ? 29.37126 34.50979  -12.71859 1.000 22.23242 ? 155  LYS B NZ  1 
ATOM   4597 N  N   . TRP B  1 125 ? 29.05420 41.29183  -13.54834 1.000 17.00761 ? 156  TRP B N   1 
ATOM   4598 C  CA  . TRP B  1 125 ? 28.06223 41.68067  -14.55153 1.000 18.29506 ? 156  TRP B CA  1 
ATOM   4599 C  C   . TRP B  1 125 ? 27.65135 40.48066  -15.40044 1.000 20.05946 ? 156  TRP B C   1 
ATOM   4600 O  O   . TRP B  1 125 ? 26.57486 39.90809  -15.18251 1.000 19.46055 ? 156  TRP B O   1 
ATOM   4601 C  CB  . TRP B  1 125 ? 28.63951 42.81632  -15.40947 1.000 18.12723 ? 156  TRP B CB  1 
ATOM   4602 C  CG  . TRP B  1 125 ? 27.70986 43.48420  -16.39119 1.000 16.71383 ? 156  TRP B CG  1 
ATOM   4603 C  CD1 . TRP B  1 125 ? 27.90399 43.61080  -17.74723 1.000 20.29518 ? 156  TRP B CD1 1 
ATOM   4604 C  CD2 . TRP B  1 125 ? 26.48825 44.18515  -16.09735 1.000 17.61403 ? 156  TRP B CD2 1 
ATOM   4605 N  NE1 . TRP B  1 125 ? 26.87711 44.34118  -18.30796 1.000 19.30957 ? 156  TRP B NE1 1 
ATOM   4606 C  CE2 . TRP B  1 125 ? 25.99490 44.69891  -17.32138 1.000 20.52600 ? 156  TRP B CE2 1 
ATOM   4607 C  CE3 . TRP B  1 125 ? 25.76002 44.42126  -14.92236 1.000 18.56135 ? 156  TRP B CE3 1 
ATOM   4608 C  CZ2 . TRP B  1 125 ? 24.80985 45.43317  -17.40326 1.000 19.63323 ? 156  TRP B CZ2 1 
ATOM   4609 C  CZ3 . TRP B  1 125 ? 24.58104 45.15699  -15.00479 1.000 18.61560 ? 156  TRP B CZ3 1 
ATOM   4610 C  CH2 . TRP B  1 125 ? 24.12422 45.66361  -16.23747 1.000 19.12454 ? 156  TRP B CH2 1 
ATOM   4611 N  N   . HIS B  1 126 ? 28.49394 40.08977  -16.36837 1.000 19.19154 ? 157  HIS B N   1 
ATOM   4612 C  CA  . HIS B  1 126 ? 28.29919 38.91006  -17.21516 1.000 18.17546 ? 157  HIS B CA  1 
ATOM   4613 C  C   . HIS B  1 126 ? 27.17434 39.09253  -18.22427 1.000 18.48159 ? 157  HIS B C   1 
ATOM   4614 O  O   . HIS B  1 126 ? 26.61053 38.10477  -18.70689 1.000 21.33891 ? 157  HIS B O   1 
ATOM   4615 C  CB  . HIS B  1 126 ? 28.04626 37.64170  -16.37191 1.000 18.92874 ? 157  HIS B CB  1 
ATOM   4616 C  CG  . HIS B  1 126 ? 28.64209 36.39308  -16.94562 1.000 18.71497 ? 157  HIS B CG  1 
ATOM   4617 N  ND1 . HIS B  1 126 ? 28.39367 35.14504  -16.41389 1.000 22.07812 ? 157  HIS B ND1 1 
ATOM   4618 C  CD2 . HIS B  1 126 ? 29.46584 36.19417  -18.00213 1.000 20.92721 ? 157  HIS B CD2 1 
ATOM   4619 C  CE1 . HIS B  1 126 ? 29.05148 34.23276  -17.10778 1.000 23.59427 ? 157  HIS B CE1 1 
ATOM   4620 N  NE2 . HIS B  1 126 ? 29.70619 34.84152  -18.08041 1.000 22.05094 ? 157  HIS B NE2 1 
ATOM   4621 N  N   . LEU B  1 127 ? 26.84399 40.33964  -18.57054 1.000 17.89919 ? 158  LEU B N   1 
ATOM   4622 C  CA  . LEU B  1 127 ? 25.74239 40.63585  -19.47813 1.000 18.70090 ? 158  LEU B CA  1 
ATOM   4623 C  C   . LEU B  1 127 ? 26.21348 41.37663  -20.72173 1.000 19.05543 ? 158  LEU B C   1 
ATOM   4624 O  O   . LEU B  1 127 ? 25.38738 41.94559  -21.44686 1.000 21.17244 ? 158  LEU B O   1 
ATOM   4625 C  CB  . LEU B  1 127 ? 24.66702 41.45463  -18.75425 1.000 18.67503 ? 158  LEU B CB  1 
ATOM   4626 C  CG  . LEU B  1 127 ? 24.08863 40.74670  -17.51786 1.000 18.39053 ? 158  LEU B CG  1 
ATOM   4627 C  CD1 . LEU B  1 127 ? 23.14364 41.67761  -16.82268 1.000 21.34573 ? 158  LEU B CD1 1 
ATOM   4628 C  CD2 . LEU B  1 127 ? 23.39713 39.44820  -17.91147 1.000 21.23538 ? 158  LEU B CD2 1 
ATOM   4629 N  N   . GLY B  1 128 ? 27.51082 41.37148  -20.99040 1.000 21.46209 ? 159  GLY B N   1 
ATOM   4630 C  CA  . GLY B  1 128 ? 28.04193 42.01951  -22.17153 1.000 21.98520 ? 159  GLY B CA  1 
ATOM   4631 C  C   . GLY B  1 128 ? 29.18713 42.93560  -21.80691 1.000 21.87861 ? 159  GLY B C   1 
ATOM   4632 O  O   . GLY B  1 128 ? 29.06450 43.73711  -20.87601 1.000 20.66665 ? 159  GLY B O   1 
ATOM   4633 N  N   . ALA B  1 129 ? 30.30162 42.82918  -22.53435 1.000 21.43589 ? 160  ALA B N   1 
ATOM   4634 C  CA  . ALA B  1 129 ? 31.51778 43.57028  -22.22185 1.000 19.72801 ? 160  ALA B CA  1 
ATOM   4635 C  C   . ALA B  1 129 ? 31.80808 44.69737  -23.20406 1.000 23.26441 ? 160  ALA B C   1 
ATOM   4636 O  O   . ALA B  1 129 ? 32.82494 45.38258  -23.05196 1.000 25.23081 ? 160  ALA B O   1 
ATOM   4637 C  CB  . ALA B  1 129 ? 32.71669 42.61361  -22.16311 1.000 24.55438 ? 160  ALA B CB  1 
ATOM   4638 N  N   . ALA B  1 130 ? 30.96461 44.89681  -24.19400 1.000 22.85962 ? 161  ALA B N   1 
ATOM   4639 C  CA  . ALA B  1 130 ? 31.06038 46.01723  -25.11557 1.000 24.58780 ? 161  ALA B CA  1 
ATOM   4640 C  C   . ALA B  1 130 ? 30.33805 47.23435  -24.54950 1.000 23.48472 ? 161  ALA B C   1 
ATOM   4641 O  O   . ALA B  1 130 ? 29.43515 47.10539  -23.71144 1.000 22.98730 ? 161  ALA B O   1 
ATOM   4642 C  CB  . ALA B  1 130 ? 30.46598 45.62769  -26.46793 1.000 23.33472 ? 161  ALA B CB  1 
ATOM   4643 N  N   . PRO B  1 131 ? 30.70303 48.44145  -24.99725 1.000 24.90585 ? 162  PRO B N   1 
ATOM   4644 C  CA  . PRO B  1 131 ? 30.12178 49.66163  -24.39830 1.000 25.04004 ? 162  PRO B CA  1 
ATOM   4645 C  C   . PRO B  1 131 ? 28.59770 49.72587  -24.35169 1.000 24.03241 ? 162  PRO B C   1 
ATOM   4646 O  O   . PRO B  1 131 ? 28.05185 50.20511  -23.34993 1.000 24.80353 ? 162  PRO B O   1 
ATOM   4647 C  CB  . PRO B  1 131 ? 30.70066 50.77396  -25.28586 1.000 25.95229 ? 162  PRO B CB  1 
ATOM   4648 C  CG  . PRO B  1 131 ? 32.03742 50.23965  -25.68437 1.000 27.08962 ? 162  PRO B CG  1 
ATOM   4649 C  CD  . PRO B  1 131 ? 31.83588 48.75195  -25.89045 1.000 24.12554 ? 162  PRO B CD  1 
ATOM   4650 N  N   . LYS B  1 132 ? 27.88782 49.28745  -25.39681 1.000 23.84039 ? 163  LYS B N   1 
ATOM   4651 C  CA  . LYS B  1 132 ? 26.43237 49.42107  -25.38387 1.000 24.05905 ? 163  LYS B CA  1 
ATOM   4652 C  C   . LYS B  1 132 ? 25.78316 48.53349  -24.33030 1.000 22.95104 ? 163  LYS B C   1 
ATOM   4653 O  O   . LYS B  1 132 ? 24.61185 48.74721  -23.98817 1.000 24.00986 ? 163  LYS B O   1 
ATOM   4654 C  CB  . LYS B  1 132 ? 25.85034 49.10542  -26.76373 1.000 24.01674 ? 163  LYS B CB  1 
ATOM   4655 C  CG  . LYS B  1 132 ? 26.00169 47.66115  -27.20816 1.000 27.25629 ? 163  LYS B CG  1 
ATOM   4656 C  CD  . LYS B  1 132 ? 25.01959 47.35416  -28.32512 1.000 34.06571 ? 163  LYS B CD  1 
ATOM   4657 C  CE  . LYS B  1 132 ? 25.70310 47.04713  -29.62999 1.000 39.66190 ? 163  LYS B CE  1 
ATOM   4658 N  NZ  . LYS B  1 132 ? 24.69181 46.68557  -30.67671 1.000 37.97619 ? 163  LYS B NZ  1 
ATOM   4659 N  N   . PHE B  1 133 ? 26.51867 47.55479  -23.80900 1.000 21.25783 ? 164  PHE B N   1 
ATOM   4660 C  CA  . PHE B  1 133 ? 26.01511 46.65368  -22.77486 1.000 21.30437 ? 164  PHE B CA  1 
ATOM   4661 C  C   . PHE B  1 133 ? 26.44175 47.06707  -21.37415 1.000 21.97408 ? 164  PHE B C   1 
ATOM   4662 O  O   . PHE B  1 133 ? 26.12761 46.36136  -20.40949 1.000 22.12704 ? 164  PHE B O   1 
ATOM   4663 C  CB  . PHE B  1 133 ? 26.49343 45.22356  -23.05965 1.000 21.70250 ? 164  PHE B CB  1 
ATOM   4664 C  CG  . PHE B  1 133 ? 26.11735 44.73224  -24.42230 1.000 20.34140 ? 164  PHE B CG  1 
ATOM   4665 C  CD1 . PHE B  1 133 ? 24.78744 44.61817  -24.77771 1.000 22.35895 ? 164  PHE B CD1 1 
ATOM   4666 C  CD2 . PHE B  1 133 ? 27.09489 44.40047  -25.35765 1.000 20.63474 ? 164  PHE B CD2 1 
ATOM   4667 C  CE1 . PHE B  1 133 ? 24.42112 44.16891  -26.02853 1.000 22.03109 ? 164  PHE B CE1 1 
ATOM   4668 C  CE2 . PHE B  1 133 ? 26.73070 43.94690  -26.62300 1.000 21.43698 ? 164  PHE B CE2 1 
ATOM   4669 C  CZ  . PHE B  1 133 ? 25.38659 43.84037  -26.95669 1.000 23.56764 ? 164  PHE B CZ  1 
ATOM   4670 N  N   . HIS B  1 134 ? 27.14632 48.18188  -21.23918 1.000 22.13841 ? 165  HIS B N   1 
ATOM   4671 C  CA  . HIS B  1 134 ? 27.75624 48.53757  -19.96775 1.000 23.91645 ? 165  HIS B CA  1 
ATOM   4672 C  C   . HIS B  1 134 ? 26.68760 48.92361  -18.94582 1.000 20.57130 ? 165  HIS B C   1 
ATOM   4673 O  O   . HIS B  1 134 ? 25.66605 49.50766  -19.31527 1.000 20.35793 ? 165  HIS B O   1 
ATOM   4674 C  CB  . HIS B  1 134 ? 28.73579 49.69770  -20.16659 1.000 22.80386 ? 165  HIS B CB  1 
ATOM   4675 C  CG  . HIS B  1 134 ? 29.57737 49.99105  -18.96679 1.000 19.53099 ? 165  HIS B CG  1 
ATOM   4676 N  ND1 . HIS B  1 134 ? 29.12300 50.74359  -17.90524 1.000 20.92472 ? 165  HIS B ND1 1 
ATOM   4677 C  CD2 . HIS B  1 134 ? 30.84928 49.63924  -18.66240 1.000 23.33246 ? 165  HIS B CD2 1 
ATOM   4678 C  CE1 . HIS B  1 134 ? 30.07749 50.83822  -16.99652 1.000 24.99790 ? 165  HIS B CE1 1 
ATOM   4679 N  NE2 . HIS B  1 134 ? 31.13581 50.17724  -17.43244 1.000 22.10526 ? 165  HIS B NE2 1 
ATOM   4680 N  N   . PRO B  1 135 ? 26.89355 48.59725  -17.65727 1.000 20.88518 ? 166  PRO B N   1 
ATOM   4681 C  CA  . PRO B  1 135 ? 25.93576 49.02071  -16.62330 1.000 19.96447 ? 166  PRO B CA  1 
ATOM   4682 C  C   . PRO B  1 135 ? 25.51123 50.48181  -16.71918 1.000 21.74314 ? 166  PRO B C   1 
ATOM   4683 O  O   . PRO B  1 135 ? 24.32003 50.77808  -16.56533 1.000 21.84676 ? 166  PRO B O   1 
ATOM   4684 C  CB  . PRO B  1 135 ? 26.70446 48.74466  -15.32660 1.000 19.84704 ? 166  PRO B CB  1 
ATOM   4685 C  CG  . PRO B  1 135 ? 27.52629 47.51177  -15.65244 1.000 20.62911 ? 166  PRO B CG  1 
ATOM   4686 C  CD  . PRO B  1 135 ? 27.91175 47.66930  -17.12167 1.000 20.43790 ? 166  PRO B CD  1 
ATOM   4687 N  N   . ASN B  1 136 ? 26.45043 51.40228  -16.96276 1.000 22.48632 ? 167  ASN B N   1 
ATOM   4688 C  CA  . ASN B  1 136 ? 26.08392 52.81646  -17.00162 1.000 22.37510 ? 167  ASN B CA  1 
ATOM   4689 C  C   . ASN B  1 136 ? 25.13498 53.13463  -18.14751 1.000 23.36478 ? 167  ASN B C   1 
ATOM   4690 O  O   . ASN B  1 136 ? 24.42564 54.14569  -18.08614 1.000 25.75269 ? 167  ASN B O   1 
ATOM   4691 C  CB  . ASN B  1 136 ? 27.32725 53.70748  -17.11724 1.000 19.95380 ? 167  ASN B CB  1 
ATOM   4692 C  CG  . ASN B  1 136 ? 28.18924 53.69298  -15.86939 1.000 23.52976 ? 167  ASN B CG  1 
ATOM   4693 O  OD1 . ASN B  1 136 ? 29.41649 53.71948  -15.96519 1.000 26.09326 ? 167  ASN B OD1 1 
ATOM   4694 N  ND2 . ASN B  1 136 ? 27.56025 53.66319  -14.69243 1.000 22.72894 ? 167  ASN B ND2 1 
ATOM   4695 N  N   . LYS B  1 137 ? 25.12749 52.31832  -19.19870 1.000 21.48088 ? 168  LYS B N   1 
ATOM   4696 C  CA  . LYS B  1 137 ? 24.17095 52.44380  -20.29014 1.000 24.04952 ? 168  LYS B CA  1 
ATOM   4697 C  C   . LYS B  1 137 ? 22.87512 51.68846  -20.03154 1.000 23.28558 ? 168  LYS B C   1 
ATOM   4698 O  O   . LYS B  1 137 ? 21.91166 51.85675  -20.79016 1.000 28.23208 ? 168  LYS B O   1 
ATOM   4699 C  CB  . LYS B  1 137 ? 24.78650 51.92768  -21.59666 1.000 25.11859 ? 168  LYS B CB  1 
ATOM   4700 C  CG  . LYS B  1 137 ? 25.99805 52.70655  -22.06455 1.000 29.08345 ? 168  LYS B CG  1 
ATOM   4701 C  CD  . LYS B  1 137 ? 25.58219 53.97447  -22.77875 1.000 36.06343 ? 168  LYS B CD  1 
ATOM   4702 C  CE  . LYS B  1 137 ? 26.79335 54.84552  -23.10480 1.000 42.65748 ? 168  LYS B CE  1 
ATOM   4703 N  NZ  . LYS B  1 137 ? 26.39798 56.11016  -23.79101 1.000 48.86484 ? 168  LYS B NZ  1 
ATOM   4704 N  N   . ARG B  1 138 ? 22.83462 50.84694  -18.99779 1.000 21.80043 ? 169  ARG B N   1 
ATOM   4705 C  CA  . ARG B  1 138 ? 21.68995 49.98422  -18.72783 1.000 20.46396 ? 169  ARG B CA  1 
ATOM   4706 C  C   . ARG B  1 138 ? 20.97478 50.37957  -17.44062 1.000 22.70917 ? 169  ARG B C   1 
ATOM   4707 O  O   . ARG B  1 138 ? 20.43410 49.51488  -16.74361 1.000 24.11779 ? 169  ARG B O   1 
ATOM   4708 C  CB  . ARG B  1 138 ? 22.10154 48.51189  -18.63835 1.000 22.30471 ? 169  ARG B CB  1 
ATOM   4709 C  CG  . ARG B  1 138 ? 22.93298 47.91092  -19.79119 1.000 26.82721 ? 169  ARG B CG  1 
ATOM   4710 C  CD  . ARG B  1 138 ? 22.23649 47.88716  -21.14875 1.000 26.60169 ? 169  ARG B CD  1 
ATOM   4711 N  NE  . ARG B  1 138 ? 20.94847 47.20200  -21.19643 1.000 22.51155 ? 169  ARG B NE  1 
ATOM   4712 C  CZ  . ARG B  1 138 ? 20.66653 46.13571  -21.93179 1.000 19.96090 ? 169  ARG B CZ  1 
ATOM   4713 N  NH1 . ARG B  1 138 ? 21.61777 45.40916  -22.50927 1.000 24.21132 ? 169  ARG B NH1 1 
ATOM   4714 N  NH2 . ARG B  1 138 ? 19.39075 45.80979  -22.12994 1.000 21.52055 ? 169  ARG B NH2 1 
ATOM   4715 N  N   . GLY B  1 139 ? 21.00244 51.66241  -17.08741 1.000 22.45899 ? 170  GLY B N   1 
ATOM   4716 C  CA  . GLY B  1 139 ? 20.20850 52.15044  -15.97244 1.000 22.28850 ? 170  GLY B CA  1 
ATOM   4717 C  C   . GLY B  1 139 ? 20.90042 52.23835  -14.63140 1.000 21.67400 ? 170  GLY B C   1 
ATOM   4718 O  O   . GLY B  1 139 ? 20.22080 52.45978  -13.62142 1.000 23.43561 ? 170  GLY B O   1 
ATOM   4719 N  N   . PHE B  1 140 ? 22.22063 52.08587  -14.57246 1.000 19.96134 ? 171  PHE B N   1 
ATOM   4720 C  CA  . PHE B  1 140 ? 22.94972 52.18475  -13.31097 1.000 19.50662 ? 171  PHE B CA  1 
ATOM   4721 C  C   . PHE B  1 140 ? 23.74462 53.48585  -13.26064 1.000 22.30656 ? 171  PHE B C   1 
ATOM   4722 O  O   . PHE B  1 140 ? 24.64385 53.70031  -14.08250 1.000 22.62310 ? 171  PHE B O   1 
ATOM   4723 C  CB  . PHE B  1 140 ? 23.87078 50.97995  -13.12323 1.000 18.79359 ? 171  PHE B CB  1 
ATOM   4724 C  CG  . PHE B  1 140 ? 23.13139 49.70805  -12.78709 1.000 18.43942 ? 171  PHE B CG  1 
ATOM   4725 C  CD1 . PHE B  1 140 ? 22.57685 49.52544  -11.53252 1.000 19.26571 ? 171  PHE B CD1 1 
ATOM   4726 C  CD2 . PHE B  1 140 ? 22.98246 48.70790  -13.73127 1.000 21.19110 ? 171  PHE B CD2 1 
ATOM   4727 C  CE1 . PHE B  1 140 ? 21.89624 48.34743  -11.21394 1.000 18.63050 ? 171  PHE B CE1 1 
ATOM   4728 C  CE2 . PHE B  1 140 ? 22.30831 47.52747  -13.42026 1.000 17.46262 ? 171  PHE B CE2 1 
ATOM   4729 C  CZ  . PHE B  1 140 ? 21.76962 47.35294  -12.15853 1.000 18.43731 ? 171  PHE B CZ  1 
ATOM   4730 N  N   . ASP B  1 141 ? 23.41491 54.34530  -12.28590 1.000 21.75754 ? 172  ASP B N   1 
ATOM   4731 C  CA  . ASP B  1 141 ? 24.18834 55.56925  -12.06415 1.000 19.43462 ? 172  ASP B CA  1 
ATOM   4732 C  C   . ASP B  1 141 ? 25.64116 55.25742  -11.72942 1.000 22.32878 ? 172  ASP B C   1 
ATOM   4733 O  O   . ASP B  1 141 ? 26.55504 55.97442  -12.15701 1.000 23.38906 ? 172  ASP B O   1 
ATOM   4734 C  CB  . ASP B  1 141 ? 23.56401 56.38806  -10.93295 1.000 21.63370 ? 172  ASP B CB  1 
ATOM   4735 C  CG  . ASP B  1 141 ? 22.16624 56.88632  -11.27026 1.000 25.29309 ? 172  ASP B CG  1 
ATOM   4736 O  OD1 . ASP B  1 141 ? 21.94964 57.33546  -12.41302 1.000 26.42063 ? 172  ASP B OD1 1 
ATOM   4737 O  OD2 . ASP B  1 141 ? 21.28013 56.82848  -10.38917 1.000 22.78119 ? 172  ASP B OD2 1 
ATOM   4738 N  N   . ASP B  1 142 ? 25.87768 54.20177  -10.94987 1.000 20.50672 ? 173  ASP B N   1 
ATOM   4739 C  CA  . ASP B  1 142 ? 27.22038 53.81509  -10.54735 1.000 20.86964 ? 173  ASP B CA  1 
ATOM   4740 C  C   . ASP B  1 142 ? 27.43503 52.34098  -10.84703 1.000 23.79094 ? 173  ASP B C   1 
ATOM   4741 O  O   . ASP B  1 142 ? 26.51023 51.53332  -10.70932 1.000 21.28165 ? 173  ASP B O   1 
ATOM   4742 C  CB  . ASP B  1 142 ? 27.45836 54.07087  -9.05272  1.000 22.04719 ? 173  ASP B CB  1 
ATOM   4743 C  CG  . ASP B  1 142 ? 28.93370 54.03976  -8.68540  1.000 29.36250 ? 173  ASP B CG  1 
ATOM   4744 O  OD1 . ASP B  1 142 ? 29.61083 55.08638  -8.83366  1.000 29.74287 ? 173  ASP B OD1 1 
ATOM   4745 O  OD2 . ASP B  1 142 ? 29.42891 52.96412  -8.26980  1.000 30.95992 ? 173  ASP B OD2 1 
ATOM   4746 N  N   . PHE B  1 143 ? 28.65384 52.00110  -11.26466 1.000 21.21289 ? 174  PHE B N   1 
ATOM   4747 C  CA  . PHE B  1 143 ? 29.07865 50.61417  -11.41057 1.000 19.72916 ? 174  PHE B CA  1 
ATOM   4748 C  C   . PHE B  1 143 ? 30.47518 50.47794  -10.83033 1.000 21.17455 ? 174  PHE B C   1 
ATOM   4749 O  O   . PHE B  1 143 ? 31.36720 51.26255  -11.17103 1.000 20.62305 ? 174  PHE B O   1 
ATOM   4750 C  CB  . PHE B  1 143 ? 29.08567 50.16550  -12.87728 1.000 20.29652 ? 174  PHE B CB  1 
ATOM   4751 C  CG  . PHE B  1 143 ? 29.64671 48.78090  -13.08266 1.000 19.85318 ? 174  PHE B CG  1 
ATOM   4752 C  CD1 . PHE B  1 143 ? 29.09701 47.69683  -12.41035 1.000 19.82311 ? 174  PHE B CD1 1 
ATOM   4753 C  CD2 . PHE B  1 143 ? 30.71431 48.56219  -13.94382 1.000 20.81251 ? 174  PHE B CD2 1 
ATOM   4754 C  CE1 . PHE B  1 143 ? 29.60532 46.42156  -12.57644 1.000 18.46388 ? 174  PHE B CE1 1 
ATOM   4755 C  CE2 . PHE B  1 143 ? 31.23074 47.27901  -14.12569 1.000 22.03011 ? 174  PHE B CE2 1 
ATOM   4756 C  CZ  . PHE B  1 143 ? 30.66863 46.20363  -13.44295 1.000 22.73287 ? 174  PHE B CZ  1 
ATOM   4757 N  N   . TYR B  1 144 ? 30.66193 49.47775  -9.96912  1.000 19.76740 ? 175  TYR B N   1 
ATOM   4758 C  CA  . TYR B  1 144 ? 31.97342 49.11847  -9.43791  1.000 18.53846 ? 175  TYR B CA  1 
ATOM   4759 C  C   . TYR B  1 144 ? 32.08970 47.60332  -9.52149  1.000 20.90830 ? 175  TYR B C   1 
ATOM   4760 O  O   . TYR B  1 144 ? 31.35141 46.89270  -8.83878  1.000 20.13380 ? 175  TYR B O   1 
ATOM   4761 C  CB  . TYR B  1 144 ? 32.14314 49.59689  -7.99556  1.000 22.24627 ? 175  TYR B CB  1 
ATOM   4762 C  CG  . TYR B  1 144 ? 33.53667 49.36862  -7.44898  1.000 21.39893 ? 175  TYR B CG  1 
ATOM   4763 C  CD1 . TYR B  1 144 ? 33.92061 48.12151  -6.95518  1.000 20.38688 ? 175  TYR B CD1 1 
ATOM   4764 C  CD2 . TYR B  1 144 ? 34.47520 50.39653  -7.43988  1.000 22.08532 ? 175  TYR B CD2 1 
ATOM   4765 C  CE1 . TYR B  1 144 ? 35.19464 47.90409  -6.46624  1.000 21.96249 ? 175  TYR B CE1 1 
ATOM   4766 C  CE2 . TYR B  1 144 ? 35.75598 50.18549  -6.94620  1.000 24.94014 ? 175  TYR B CE2 1 
ATOM   4767 C  CZ  . TYR B  1 144 ? 36.10629 48.93438  -6.47122  1.000 23.48885 ? 175  TYR B CZ  1 
ATOM   4768 O  OH  . TYR B  1 144 ? 37.36795 48.70451  -5.97397  1.000 24.98139 ? 175  TYR B OH  1 
ATOM   4769 N  N   . GLY B  1 145 ? 32.98589 47.10779  -10.36313 1.000 21.33916 ? 176  GLY B N   1 
ATOM   4770 C  CA  . GLY B  1 145 ? 33.13454 45.65602  -10.45841 1.000 19.30554 ? 176  GLY B CA  1 
ATOM   4771 C  C   . GLY B  1 145 ? 33.81681 45.25464  -11.75411 1.000 21.37745 ? 176  GLY B C   1 
ATOM   4772 O  O   . GLY B  1 145 ? 34.69901 45.95552  -12.24645 1.000 22.24841 ? 176  GLY B O   1 
ATOM   4773 N  N   . PHE B  1 146 ? 33.40313 44.09903  -12.27321 1.000 20.43719 ? 177  PHE B N   1 
ATOM   4774 C  CA  . PHE B  1 146 ? 34.01184 43.52801  -13.46713 1.000 20.44873 ? 177  PHE B CA  1 
ATOM   4775 C  C   . PHE B  1 146 ? 32.93039 43.06185  -14.43119 1.000 22.38880 ? 177  PHE B C   1 
ATOM   4776 O  O   . PHE B  1 146 ? 31.83415 42.66298  -14.02277 1.000 20.90780 ? 177  PHE B O   1 
ATOM   4777 C  CB  . PHE B  1 146 ? 34.97527 42.37333  -13.10846 1.000 21.53113 ? 177  PHE B CB  1 
ATOM   4778 C  CG  . PHE B  1 146 ? 34.33403 41.23703  -12.35807 1.000 19.35933 ? 177  PHE B CG  1 
ATOM   4779 C  CD1 . PHE B  1 146 ? 33.71901 40.19546  -13.04328 1.000 18.82646 ? 177  PHE B CD1 1 
ATOM   4780 C  CD2 . PHE B  1 146 ? 34.35613 41.20136  -10.97009 1.000 21.00454 ? 177  PHE B CD2 1 
ATOM   4781 C  CE1 . PHE B  1 146 ? 33.13530 39.13069  -12.35818 1.000 21.49038 ? 177  PHE B CE1 1 
ATOM   4782 C  CE2 . PHE B  1 146 ? 33.77696 40.14507  -10.27814 1.000 20.86754 ? 177  PHE B CE2 1 
ATOM   4783 C  CZ  . PHE B  1 146 ? 33.16698 39.10063  -10.97775 1.000 18.84700 ? 177  PHE B CZ  1 
ATOM   4784 N  N   . LEU B  1 147 ? 33.24624 43.11127  -15.72565 1.000 21.23314 ? 178  LEU B N   1 
ATOM   4785 C  CA  . LEU B  1 147 ? 32.21505 42.91737  -16.73893 1.000 20.10596 ? 178  LEU B CA  1 
ATOM   4786 C  C   . LEU B  1 147 ? 31.94609 41.45147  -17.07549 1.000 19.25085 ? 178  LEU B C   1 
ATOM   4787 O  O   . LEU B  1 147 ? 30.84067 41.13703  -17.54183 1.000 21.96014 ? 178  LEU B O   1 
ATOM   4788 C  CB  . LEU B  1 147 ? 32.58944 43.67750  -18.01622 1.000 22.02547 ? 178  LEU B CB  1 
ATOM   4789 C  CG  . LEU B  1 147 ? 32.63215 45.20724  -17.86137 1.000 22.53549 ? 178  LEU B CG  1 
ATOM   4790 C  CD1 . LEU B  1 147 ? 33.21852 45.84139  -19.12712 1.000 22.46752 ? 178  LEU B CD1 1 
ATOM   4791 C  CD2 . LEU B  1 147 ? 31.23648 45.77788  -17.59166 1.000 22.46629 ? 178  LEU B CD2 1 
ATOM   4792 N  N   . GLY B  1 148 ? 32.91193 40.55791  -16.85342 1.000 22.81636 ? 179  GLY B N   1 
ATOM   4793 C  CA  . GLY B  1 148 ? 32.82100 39.16149  -17.26732 1.000 21.44703 ? 179  GLY B CA  1 
ATOM   4794 C  C   . GLY B  1 148 ? 32.23536 38.23851  -16.21969 1.000 21.43649 ? 179  GLY B C   1 
ATOM   4795 O  O   . GLY B  1 148 ? 31.44273 38.65091  -15.36583 1.000 20.87094 ? 179  GLY B O   1 
ATOM   4796 N  N   . GLY B  1 149 ? 32.62846 36.96193  -16.28885 1.000 20.97705 ? 180  GLY B N   1 
ATOM   4797 C  CA  . GLY B  1 149 ? 31.95813 35.92601  -15.51382 1.000 20.95183 ? 180  GLY B CA  1 
ATOM   4798 C  C   . GLY B  1 149 ? 32.59482 35.54010  -14.19336 1.000 22.04445 ? 180  GLY B C   1 
ATOM   4799 O  O   . GLY B  1 149 ? 32.01965 34.76060  -13.42620 1.000 21.46600 ? 180  GLY B O   1 
ATOM   4800 N  N   . GLY B  1 150 ? 33.77825 36.06356  -13.90557 1.000 21.23450 ? 181  GLY B N   1 
ATOM   4801 C  CA  . GLY B  1 150 ? 34.41925 35.74898  -12.64131 1.000 20.52003 ? 181  GLY B CA  1 
ATOM   4802 C  C   . GLY B  1 150 ? 35.66093 36.58624  -12.45152 1.000 21.47287 ? 181  GLY B C   1 
ATOM   4803 O  O   . GLY B  1 150 ? 36.08640 37.31894  -13.35077 1.000 22.40030 ? 181  GLY B O   1 
ATOM   4804 N  N   . HIS B  1 151 ? 36.25039 36.46068  -11.26382 1.000 19.83523 ? 182  HIS B N   1 
ATOM   4805 C  CA  . HIS B  1 151 ? 37.43999 37.24654  -10.97170 1.000 20.65390 ? 182  HIS B CA  1 
ATOM   4806 C  C   . HIS B  1 151 ? 38.20806 36.63197  -9.80977  1.000 21.78469 ? 182  HIS B C   1 
ATOM   4807 O  O   . HIS B  1 151 ? 37.60748 36.12540  -8.86076  1.000 22.45700 ? 182  HIS B O   1 
ATOM   4808 C  CB  . HIS B  1 151 ? 37.06763 38.70687  -10.65407 1.000 20.65278 ? 182  HIS B CB  1 
ATOM   4809 C  CG  . HIS B  1 151 ? 38.13978 39.68335  -11.01912 1.000 20.96518 ? 182  HIS B CG  1 
ATOM   4810 N  ND1 . HIS B  1 151 ? 39.26896 39.86896  -10.25003 1.000 22.61766 ? 182  HIS B ND1 1 
ATOM   4811 C  CD2 . HIS B  1 151 ? 38.26902 40.50439  -12.08647 1.000 20.62891 ? 182  HIS B CD2 1 
ATOM   4812 C  CE1 . HIS B  1 151 ? 40.05004 40.76232  -10.82976 1.000 22.24459 ? 182  HIS B CE1 1 
ATOM   4813 N  NE2 . HIS B  1 151 ? 39.46502 41.16683  -11.94404 1.000 23.21469 ? 182  HIS B NE2 1 
ATOM   4814 N  N   . ASP B  1 152 ? 39.53934 36.68320  -9.88883  1.000 20.45928 ? 183  ASP B N   1 
ATOM   4815 C  CA  . ASP B  1 152 ? 40.35162 36.33928  -8.72989  1.000 18.93318 ? 183  ASP B CA  1 
ATOM   4816 C  C   . ASP B  1 152 ? 40.11099 37.34571  -7.60804  1.000 19.94174 ? 183  ASP B C   1 
ATOM   4817 O  O   . ASP B  1 152 ? 39.75100 38.50144  -7.84479  1.000 20.74753 ? 183  ASP B O   1 
ATOM   4818 C  CB  . ASP B  1 152 ? 41.83486 36.29894  -9.10954  1.000 21.44228 ? 183  ASP B CB  1 
ATOM   4819 C  CG  . ASP B  1 152 ? 42.18245 35.11183  -9.99818  1.000 28.77213 ? 183  ASP B CG  1 
ATOM   4820 O  OD1 . ASP B  1 152 ? 41.26761 34.45154  -10.53793 1.000 25.81947 ? 183  ASP B OD1 1 
ATOM   4821 O  OD2 . ASP B  1 152 ? 43.39110 34.84145  -10.16079 1.000 37.12327 ? 183  ASP B OD2 1 
ATOM   4822 N  N   . TYR B  1 153 ? 40.30544 36.89293  -6.36960  1.000 20.08140 ? 184  TYR B N   1 
ATOM   4823 C  CA  . TYR B  1 153 ? 39.80752 37.61079  -5.20112  1.000 19.24921 ? 184  TYR B CA  1 
ATOM   4824 C  C   . TYR B  1 153 ? 40.81708 38.54109  -4.53909  1.000 18.72265 ? 184  TYR B C   1 
ATOM   4825 O  O   . TYR B  1 153 ? 40.40155 39.42676  -3.78254  1.000 20.27733 ? 184  TYR B O   1 
ATOM   4826 C  CB  . TYR B  1 153 ? 39.30461 36.61656  -4.14558  1.000 19.87587 ? 184  TYR B CB  1 
ATOM   4827 C  CG  . TYR B  1 153 ? 37.98580 35.97427  -4.48695  1.000 19.02913 ? 184  TYR B CG  1 
ATOM   4828 C  CD1 . TYR B  1 153 ? 37.92666 34.87534  -5.34411  1.000 19.10808 ? 184  TYR B CD1 1 
ATOM   4829 C  CD2 . TYR B  1 153 ? 36.79350 36.47523  -3.96670  1.000 19.11588 ? 184  TYR B CD2 1 
ATOM   4830 C  CE1 . TYR B  1 153 ? 36.71131 34.27554  -5.66578  1.000 18.38398 ? 184  TYR B CE1 1 
ATOM   4831 C  CE2 . TYR B  1 153 ? 35.56921 35.88604  -4.28745  1.000 19.64956 ? 184  TYR B CE2 1 
ATOM   4832 C  CZ  . TYR B  1 153 ? 35.53731 34.78095  -5.12597  1.000 19.11588 ? 184  TYR B CZ  1 
ATOM   4833 O  OH  . TYR B  1 153 ? 34.32820 34.18837  -5.45833  1.000 19.21271 ? 184  TYR B OH  1 
ATOM   4834 N  N   . PHE B  1 154 ? 42.12595 38.36565  -4.76872  1.000 19.77207 ? 185  PHE B N   1 
ATOM   4835 C  CA  . PHE B  1 154 ? 43.10495 39.16558  -4.03730  1.000 20.14447 ? 185  PHE B CA  1 
ATOM   4836 C  C   . PHE B  1 154 ? 43.82986 40.11437  -4.98210  1.000 22.21235 ? 185  PHE B C   1 
ATOM   4837 O  O   . PHE B  1 154 ? 44.58485 39.65330  -5.85433  1.000 24.71703 ? 185  PHE B O   1 
ATOM   4838 C  CB  . PHE B  1 154 ? 44.11065 38.26570  -3.31661  1.000 22.89476 ? 185  PHE B CB  1 
ATOM   4839 C  CG  . PHE B  1 154 ? 43.56571 37.61184  -2.07972  1.000 23.06168 ? 185  PHE B CG  1 
ATOM   4840 C  CD1 . PHE B  1 154 ? 43.53886 38.29314  -0.87188  1.000 22.11107 ? 185  PHE B CD1 1 
ATOM   4841 C  CD2 . PHE B  1 154 ? 43.09697 36.30747  -2.12237  1.000 22.64335 ? 185  PHE B CD2 1 
ATOM   4842 C  CE1 . PHE B  1 154 ? 43.04435 37.68486  0.27259   1.000 22.67289 ? 185  PHE B CE1 1 
ATOM   4843 C  CE2 . PHE B  1 154 ? 42.60352 35.70024  -0.98667  1.000 22.55937 ? 185  PHE B CE2 1 
ATOM   4844 C  CZ  . PHE B  1 154 ? 42.56989 36.38652  0.20957   1.000 21.06653 ? 185  PHE B CZ  1 
ATOM   4845 N  N   . PRO B  1 155 ? 43.62615 41.42895  -4.85623  1.000 22.16112 ? 186  PRO B N   1 
ATOM   4846 C  CA  . PRO B  1 155 ? 44.27907 42.36894  -5.78769  1.000 23.31165 ? 186  PRO B CA  1 
ATOM   4847 C  C   . PRO B  1 155 ? 45.79013 42.26508  -5.78237  1.000 27.58654 ? 186  PRO B C   1 
ATOM   4848 O  O   . PRO B  1 155 ? 46.41001 42.37440  -6.84456  1.000 27.32117 ? 186  PRO B O   1 
ATOM   4849 C  CB  . PRO B  1 155 ? 43.80749 43.74420  -5.29289  1.000 25.85257 ? 186  PRO B CB  1 
ATOM   4850 C  CG  . PRO B  1 155 ? 42.56972 43.48254  -4.54404  1.000 27.10266 ? 186  PRO B CG  1 
ATOM   4851 C  CD  . PRO B  1 155 ? 42.69954 42.10866  -3.93572  1.000 22.38937 ? 186  PRO B CD  1 
ATOM   4852 N  N   . SER B  1 156 ? 46.39982 42.03767  -4.61894  1.000 29.08525 ? 187  SER B N   1 
ATOM   4853 C  CA  . SER B  1 156 ? 47.85020 41.87032  -4.57140  1.000 31.71667 ? 187  SER B CA  1 
ATOM   4854 C  C   . SER B  1 156 ? 48.31509 40.70687  -5.43891  1.000 34.43136 ? 187  SER B C   1 
ATOM   4855 O  O   . SER B  1 156 ? 49.45827 40.70454  -5.91351  1.000 35.74468 ? 187  SER B O   1 
ATOM   4856 C  CB  . SER B  1 156 ? 48.30975 41.66880  -3.12976  1.000 26.42358 ? 187  SER B CB  1 
ATOM   4857 O  OG  . SER B  1 156 ? 47.73278 40.51007  -2.55765  1.000 35.28564 ? 187  SER B OG  1 
ATOM   4858 N  N   . GLU B  1 157 ? 47.45088 39.71635  -5.66201  1.000 28.32274 ? 188  GLU B N   1 
ATOM   4859 C  CA  . GLU B  1 157 ? 47.77827 38.57973  -6.51401  1.000 27.89670 ? 188  GLU B CA  1 
ATOM   4860 C  C   . GLU B  1 157 ? 47.43064 38.83517  -7.97596  1.000 32.66416 ? 188  GLU B C   1 
ATOM   4861 O  O   . GLU B  1 157 ? 48.27514 38.64014  -8.85733  1.000 30.74807 ? 188  GLU B O   1 
ATOM   4862 C  CB  . GLU B  1 157 ? 47.06576 37.31511  -6.00931  1.000 28.10392 ? 188  GLU B CB  1 
ATOM   4863 C  CG  . GLU B  1 157 ? 47.52659 36.87661  -4.62439  1.000 25.90578 ? 188  GLU B CG  1 
ATOM   4864 C  CD  . GLU B  1 157 ? 46.87218 35.57832  -4.13357  1.000 41.72418 ? 188  GLU B CD  1 
ATOM   4865 O  OE1 . GLU B  1 157 ? 45.75057 35.23044  -4.57873  1.000 34.12015 ? 188  GLU B OE1 1 
ATOM   4866 O  OE2 . GLU B  1 157 ? 47.49083 34.89948  -3.28811  1.000 44.48076 ? 188  GLU B OE2 1 
ATOM   4867 N  N   . TYR B  1 158 ? 46.20083 39.27434  -8.26509  1.000 25.76405 ? 189  TYR B N   1 
ATOM   4868 C  CA  . TYR B  1 158 ? 45.81829 39.35571  -9.66863  1.000 25.65768 ? 189  TYR B CA  1 
ATOM   4869 C  C   . TYR B  1 158 ? 46.41328 40.57640  -10.35716 1.000 27.94140 ? 189  TYR B C   1 
ATOM   4870 O  O   . TYR B  1 158 ? 46.66638 40.52437  -11.56205 1.000 31.04081 ? 189  TYR B O   1 
ATOM   4871 C  CB  . TYR B  1 158 ? 44.28767 39.31810  -9.84544  1.000 28.79082 ? 189  TYR B CB  1 
ATOM   4872 C  CG  . TYR B  1 158 ? 43.44122 40.49470  -9.35657  1.000 27.83705 ? 189  TYR B CG  1 
ATOM   4873 C  CD1 . TYR B  1 158 ? 43.48331 41.74654  -9.98210  1.000 25.43144 ? 189  TYR B CD1 1 
ATOM   4874 C  CD2 . TYR B  1 158 ? 42.53461 40.32168  -8.31579  1.000 23.61701 ? 189  TYR B CD2 1 
ATOM   4875 C  CE1 . TYR B  1 158 ? 42.68162 42.80268  -9.53711  1.000 25.56503 ? 189  TYR B CE1 1 
ATOM   4876 C  CE2 . TYR B  1 158 ? 41.72833 41.35818  -7.87563  1.000 24.30058 ? 189  TYR B CE2 1 
ATOM   4877 C  CZ  . TYR B  1 158 ? 41.80664 42.59388  -8.48494  1.000 24.06099 ? 189  TYR B CZ  1 
ATOM   4878 O  OH  . TYR B  1 158 ? 40.99372 43.62315  -8.04258  1.000 24.89907 ? 189  TYR B OH  1 
ATOM   4879 N  N   . GLN B  1 159 ? 46.63256 41.67422  -9.62668  1.000 30.54368 ? 190  GLN B N   1 
ATOM   4880 C  CA  . GLN B  1 159 ? 47.30265 42.82195  -10.23285 1.000 31.20567 ? 190  GLN B CA  1 
ATOM   4881 C  C   . GLN B  1 159 ? 48.74314 42.47901  -10.59435 1.000 35.97352 ? 190  GLN B C   1 
ATOM   4882 O  O   . GLN B  1 159 ? 49.25440 42.94589  -11.61980 1.000 34.66204 ? 190  GLN B O   1 
ATOM   4883 C  CB  . GLN B  1 159 ? 47.23470 44.03429  -9.29510  1.000 31.47603 ? 190  GLN B CB  1 
ATOM   4884 C  CG  . GLN B  1 159 ? 45.82602 44.62512  -9.15820  1.000 30.41839 ? 190  GLN B CG  1 
ATOM   4885 C  CD  . GLN B  1 159 ? 45.64527 45.56085  -7.96059  1.000 35.25907 ? 190  GLN B CD  1 
ATOM   4886 O  OE1 . GLN B  1 159 ? 46.54976 45.74348  -7.14130  1.000 34.19964 ? 190  GLN B OE1 1 
ATOM   4887 N  NE2 . GLN B  1 159 ? 44.45135 46.14194  -7.84750  1.000 33.42571 ? 190  GLN B NE2 1 
ATOM   4888 N  N   . LYS B  1 160 ? 49.39643 41.63552  -9.79045  1.000 31.69347 ? 191  LYS B N   1 
ATOM   4889 C  CA  . LYS B  1 160 ? 50.75367 41.21016  -10.11384 1.000 33.30603 ? 191  LYS B CA  1 
ATOM   4890 C  C   . LYS B  1 160 ? 50.76528 40.33804  -11.36054 1.000 39.56946 ? 191  LYS B C   1 
ATOM   4891 O  O   . LYS B  1 160 ? 51.60486 40.52092  -12.25037 1.000 38.25077 ? 191  LYS B O   1 
ATOM   4892 C  CB  . LYS B  1 160 ? 51.37324 40.47061  -8.92695  1.000 35.21049 ? 191  LYS B CB  1 
ATOM   4893 C  CG  . LYS B  1 160 ? 52.76550 39.91305  -9.21305  1.000 40.84219 ? 191  LYS B CG  1 
ATOM   4894 C  CD  . LYS B  1 160 ? 53.52575 39.58487  -7.93577  1.000 46.79174 ? 191  LYS B CD  1 
ATOM   4895 C  CE  . LYS B  1 160 ? 52.98589 38.34028  -7.25109  1.000 55.19589 ? 191  LYS B CE  1 
ATOM   4896 N  NZ  . LYS B  1 160 ? 53.75270 38.02294  -6.00748  1.000 64.67354 ? 191  LYS B NZ  1 
ATOM   4897 N  N   . THR B  1 161 ? 49.83145 39.38470  -11.44252 1.000 35.35542 ? 192  THR B N   1 
ATOM   4898 C  CA  . THR B  1 161 ? 49.74768 38.51286  -12.60960 1.000 33.06432 ? 192  THR B CA  1 
ATOM   4899 C  C   . THR B  1 161 ? 49.40340 39.30615  -13.86263 1.000 37.30692 ? 192  THR B C   1 
ATOM   4900 O  O   . THR B  1 161 ? 50.01042 39.11501  -14.92335 1.000 35.14496 ? 192  THR B O   1 
ATOM   4901 C  CB  . THR B  1 161 ? 48.70718 37.42237  -12.36463 1.000 32.82781 ? 192  THR B CB  1 
ATOM   4902 O  OG1 . THR B  1 161 ? 49.08500 36.66525  -11.20823 1.000 32.90472 ? 192  THR B OG1 1 
ATOM   4903 C  CG2 . THR B  1 161 ? 48.60268 36.49608  -13.57129 1.000 36.59577 ? 192  THR B CG2 1 
ATOM   4904 N  N   . TYR B  1 162 ? 48.42349 40.20359  -13.75649 1.000 31.96641 ? 193  TYR B N   1 
ATOM   4905 C  CA  . TYR B  1 162 ? 48.00809 40.98971  -14.91194 1.000 32.80827 ? 193  TYR B CA  1 
ATOM   4906 C  C   . TYR B  1 162 ? 49.16906 41.80662  -15.46712 1.000 39.94029 ? 193  TYR B C   1 
ATOM   4907 O  O   . TYR B  1 162 ? 49.43986 41.78396  -16.67392 1.000 40.05358 ? 193  TYR B O   1 
ATOM   4908 C  CB  . TYR B  1 162 ? 46.84446 41.90134  -14.52829 1.000 33.22048 ? 193  TYR B CB  1 
ATOM   4909 C  CG  . TYR B  1 162 ? 46.43275 42.81940  -15.64466 1.000 31.10770 ? 193  TYR B CG  1 
ATOM   4910 C  CD1 . TYR B  1 162 ? 45.66125 42.35276  -16.69971 1.000 32.24127 ? 193  TYR B CD1 1 
ATOM   4911 C  CD2 . TYR B  1 162 ? 46.82637 44.15299  -15.65313 1.000 36.95088 ? 193  TYR B CD2 1 
ATOM   4912 C  CE1 . TYR B  1 162 ? 45.28595 43.18670  -17.73049 1.000 32.61448 ? 193  TYR B CE1 1 
ATOM   4913 C  CE2 . TYR B  1 162 ? 46.45519 44.99863  -16.68177 1.000 31.60399 ? 193  TYR B CE2 1 
ATOM   4914 C  CZ  . TYR B  1 162 ? 45.68529 44.51015  -17.71533 1.000 35.07216 ? 193  TYR B CZ  1 
ATOM   4915 O  OH  . TYR B  1 162 ? 45.30933 45.33953  -18.74299 1.000 35.88144 ? 193  TYR B OH  1 
ATOM   4916 N  N   . LYS B  1 163 ? 49.86898 42.53460  -14.59516 1.000 36.87955 ? 194  LYS B N   1 
ATOM   4917 C  CA  . LYS B  1 163 ? 50.97735 43.36595  -15.05404 1.000 39.99668 ? 194  LYS B CA  1 
ATOM   4918 C  C   . LYS B  1 163 ? 52.09025 42.51778  -15.65899 1.000 43.94052 ? 194  LYS B C   1 
ATOM   4919 O  O   . LYS B  1 163 ? 52.68984 42.89790  -16.67244 1.000 45.37853 ? 194  LYS B O   1 
ATOM   4920 C  CB  . LYS B  1 163 ? 51.50501 44.21524  -13.89631 1.000 39.81655 ? 194  LYS B CB  1 
ATOM   4921 C  CG  . LYS B  1 163 ? 50.49095 45.21297  -13.35053 1.000 43.61698 ? 194  LYS B CG  1 
ATOM   4922 C  CD  . LYS B  1 163 ? 51.05511 46.03297  -12.20050 1.000 49.34481 ? 194  LYS B CD  1 
ATOM   4923 C  CE  . LYS B  1 163 ? 49.93665 46.69989  -11.40962 1.000 49.96164 ? 194  LYS B CE  1 
ATOM   4924 N  NZ  . LYS B  1 163 ? 50.25999 48.10200  -11.03014 1.000 63.28184 ? 194  LYS B NZ  1 
ATOM   4925 N  N   . ALA B  1 164 ? 52.36860 41.35499  -15.06467 1.000 39.47965 ? 195  ALA B N   1 
ATOM   4926 C  CA  . ALA B  1 164 ? 53.44453 40.51246  -15.57539 1.000 40.54372 ? 195  ALA B CA  1 
ATOM   4927 C  C   . ALA B  1 164 ? 53.08699 39.91047  -16.92894 1.000 48.69961 ? 195  ALA B C   1 
ATOM   4928 O  O   . ALA B  1 164 ? 53.92903 39.86299  -17.83327 1.000 48.81599 ? 195  ALA B O   1 
ATOM   4929 C  CB  . ALA B  1 164 ? 53.77600 39.41059  -14.56891 1.000 40.93620 ? 195  ALA B CB  1 
ATOM   4930 N  N   . GLN B  1 165 ? 51.84835 39.43507  -17.08883 1.000 43.96564 ? 196  GLN B N   1 
ATOM   4931 C  CA  . GLN B  1 165 ? 51.46319 38.82907  -18.35888 1.000 46.24538 ? 196  GLN B CA  1 
ATOM   4932 C  C   . GLN B  1 165 ? 51.37117 39.86647  -19.46895 1.000 50.26333 ? 196  GLN B C   1 
ATOM   4933 O  O   . GLN B  1 165 ? 51.59596 39.53979  -20.63981 1.000 49.97169 ? 196  GLN B O   1 
ATOM   4934 C  CB  . GLN B  1 165 ? 50.13896 38.08078  -18.21204 1.000 45.12490 ? 196  GLN B CB  1 
ATOM   4935 C  CG  . GLN B  1 165 ? 50.25291 36.79890  -17.40698 1.000 49.61886 ? 196  GLN B CG  1 
ATOM   4936 C  CD  . GLN B  1 165 ? 51.29866 35.85059  -17.97265 1.000 62.71870 ? 196  GLN B CD  1 
ATOM   4937 O  OE1 . GLN B  1 165 ? 51.39208 35.66191  -19.18843 1.000 63.76033 ? 196  GLN B OE1 1 
ATOM   4938 N  NE2 . GLN B  1 165 ? 52.09878 35.25541  -17.09057 1.000 59.90407 ? 196  GLN B NE2 1 
ATOM   4939 N  N   . LYS B  1 166 ? 51.04349 41.11319  -19.12574 1.000 46.30800 ? 197  LYS B N   1 
ATOM   4940 C  CA  . LYS B  1 166 ? 51.07807 42.17859  -20.12082 1.000 48.61072 ? 197  LYS B CA  1 
ATOM   4941 C  C   . LYS B  1 166 ? 52.50300 42.42589  -20.59959 1.000 54.95600 ? 197  LYS B C   1 
ATOM   4942 O  O   . LYS B  1 166 ? 52.74465 42.56425  -21.80528 1.000 55.60833 ? 197  LYS B O   1 
ATOM   4943 C  CB  . LYS B  1 166 ? 50.47032 43.45804  -19.54463 1.000 43.77523 ? 197  LYS B CB  1 
ATOM   4944 N  N   . LYS B  1 167 ? 53.46187 42.47097  -19.66921 1.000 53.50408 ? 198  LYS B N   1 
ATOM   4945 C  CA  . LYS B  1 167 ? 54.86113 42.63181  -20.05411 1.000 51.96259 ? 198  LYS B CA  1 
ATOM   4946 C  C   . LYS B  1 167 ? 55.36331 41.41775  -20.82558 1.000 50.30016 ? 198  LYS B C   1 
ATOM   4947 O  O   . LYS B  1 167 ? 56.16791 41.55254  -21.75377 1.000 50.73195 ? 198  LYS B O   1 
ATOM   4948 C  CB  . LYS B  1 167 ? 55.72108 42.87787  -18.81552 1.000 51.05868 ? 198  LYS B CB  1 
ATOM   4949 N  N   . ALA B  1 168 ? 54.89458 40.22387  -20.46837 1.000 53.26386 ? 199  ALA B N   1 
ATOM   4950 C  CA  . ALA B  1 168 ? 55.25936 39.03643  -21.23150 1.000 53.86730 ? 199  ALA B CA  1 
ATOM   4951 C  C   . ALA B  1 168 ? 54.62633 39.00628  -22.61638 1.000 57.39616 ? 199  ALA B C   1 
ATOM   4952 O  O   . ALA B  1 168 ? 54.84411 38.03766  -23.35504 1.000 57.68471 ? 199  ALA B O   1 
ATOM   4953 C  CB  . ALA B  1 168 ? 54.87595 37.77486  -20.45572 1.000 55.29923 ? 199  ALA B CB  1 
ATOM   4954 N  N   . GLY B  1 169 ? 53.86615 40.03435  -22.98983 1.000 56.56437 ? 200  GLY B N   1 
ATOM   4955 C  CA  . GLY B  1 169 ? 53.22790 40.05957  -24.29611 1.000 57.90275 ? 200  GLY B CA  1 
ATOM   4956 C  C   . GLY B  1 169 ? 52.18196 38.98555  -24.48408 1.000 64.53459 ? 200  GLY B C   1 
ATOM   4957 O  O   . GLY B  1 169 ? 51.97024 38.52293  -25.61125 1.000 61.03607 ? 200  GLY B O   1 
ATOM   4958 N  N   . ASN B  1 170 ? 51.52744 38.56807  -23.40639 1.000 60.12262 ? 201  ASN B N   1 
ATOM   4959 C  CA  . ASN B  1 170 ? 50.49944 37.53729  -23.49422 1.000 58.67184 ? 201  ASN B CA  1 
ATOM   4960 C  C   . ASN B  1 170 ? 49.31460 38.06988  -24.28902 1.000 57.32312 ? 201  ASN B C   1 
ATOM   4961 O  O   . ASN B  1 170 ? 48.71981 39.08175  -23.89423 1.000 56.12410 ? 201  ASN B O   1 
ATOM   4962 C  CB  . ASN B  1 170 ? 50.06244 37.10724  -22.09247 1.000 55.82359 ? 201  ASN B CB  1 
ATOM   4963 C  CG  . ASN B  1 170 ? 49.19067 35.86128  -22.09783 1.000 55.50238 ? 201  ASN B CG  1 
ATOM   4964 O  OD1 . ASN B  1 170 ? 48.39663 35.64180  -23.01208 1.000 56.81410 ? 201  ASN B OD1 1 
ATOM   4965 N  ND2 . ASN B  1 170 ? 49.33787 35.03644  -21.06685 1.000 55.70634 ? 201  ASN B ND2 1 
ATOM   4966 N  N   . PRO B  1 171 ? 48.94585 37.44275  -25.40974 1.000 60.76687 ? 202  PRO B N   1 
ATOM   4967 C  CA  . PRO B  1 171 ? 47.75945 37.88972  -26.14942 1.000 61.16948 ? 202  PRO B CA  1 
ATOM   4968 C  C   . PRO B  1 171 ? 46.45473 37.33286  -25.60626 1.000 56.67377 ? 202  PRO B C   1 
ATOM   4969 O  O   . PRO B  1 171 ? 45.38488 37.81115  -26.00666 1.000 57.39683 ? 202  PRO B O   1 
ATOM   4970 C  CB  . PRO B  1 171 ? 48.02811 37.37105  -27.56605 1.000 57.44357 ? 202  PRO B CB  1 
ATOM   4971 C  CG  . PRO B  1 171 ? 48.79084 36.10307  -27.33393 1.000 59.37187 ? 202  PRO B CG  1 
ATOM   4972 C  CD  . PRO B  1 171 ? 49.63993 36.33792  -26.09614 1.000 60.21967 ? 202  PRO B CD  1 
ATOM   4973 N  N   . ASN B  1 172 ? 46.50770 36.34468  -24.71473 1.000 54.25245 ? 203  ASN B N   1 
ATOM   4974 C  CA  . ASN B  1 172 ? 45.30126 35.73188  -24.17685 1.000 54.24085 ? 203  ASN B CA  1 
ATOM   4975 C  C   . ASN B  1 172 ? 45.24918 35.86600  -22.65959 1.000 45.88401 ? 203  ASN B C   1 
ATOM   4976 O  O   . ASN B  1 172 ? 45.14740 34.86183  -21.94656 1.000 47.80843 ? 203  ASN B O   1 
ATOM   4977 C  CB  . ASN B  1 172 ? 45.22942 34.25751  -24.58442 1.000 57.86129 ? 203  ASN B CB  1 
ATOM   4978 N  N   . ILE B  1 173 ? 45.32168 37.09649  -22.15296 1.000 40.99630 ? 204  ILE B N   1 
ATOM   4979 C  CA  . ILE B  1 173 ? 45.21813 37.31266  -20.71475 1.000 43.00817 ? 204  ILE B CA  1 
ATOM   4980 C  C   . ILE B  1 173 ? 43.78147 37.06580  -20.27481 1.000 38.14843 ? 204  ILE B C   1 
ATOM   4981 O  O   . ILE B  1 173 ? 42.83804 37.64295  -20.83169 1.000 38.39420 ? 204  ILE B O   1 
ATOM   4982 C  CB  . ILE B  1 173 ? 45.67714 38.72979  -20.34392 1.000 40.06400 ? 204  ILE B CB  1 
ATOM   4983 C  CG1 . ILE B  1 173 ? 47.13561 38.95081  -20.75688 1.000 48.33716 ? 204  ILE B CG1 1 
ATOM   4984 C  CG2 . ILE B  1 173 ? 45.51793 38.96054  -18.85098 1.000 37.66194 ? 204  ILE B CG2 1 
ATOM   4985 C  CD1 . ILE B  1 173 ? 47.69402 40.28899  -20.30310 1.000 45.57449 ? 204  ILE B CD1 1 
ATOM   4986 N  N   . ARG B  1 174 ? 43.61038 36.20150  -19.27589 1.000 37.98715 ? 205  ARG B N   1 
ATOM   4987 C  CA  . ARG B  1 174 ? 42.27921 35.85770  -18.78773 1.000 35.40112 ? 205  ARG B CA  1 
ATOM   4988 C  C   . ARG B  1 174 ? 41.61605 37.05762  -18.12002 1.000 28.81767 ? 205  ARG B C   1 
ATOM   4989 O  O   . ARG B  1 174 ? 42.25236 37.79807  -17.36331 1.000 27.93022 ? 205  ARG B O   1 
ATOM   4990 C  CB  . ARG B  1 174 ? 42.37141 34.69455  -17.79985 1.000 33.84120 ? 205  ARG B CB  1 
ATOM   4991 C  CG  . ARG B  1 174 ? 42.77993 33.37748  -18.44533 1.000 44.56750 ? 205  ARG B CG  1 
ATOM   4992 C  CD  . ARG B  1 174 ? 41.70550 32.90595  -19.42059 1.000 50.40443 ? 205  ARG B CD  1 
ATOM   4993 N  NE  . ARG B  1 174 ? 40.45267 32.72872  -18.70895 1.000 55.05985 ? 205  ARG B NE  1 
ATOM   4994 C  CZ  . ARG B  1 174 ? 40.08508 31.59469  -18.13321 1.000 58.32941 ? 205  ARG B CZ  1 
ATOM   4995 N  NH1 . ARG B  1 174 ? 40.75959 30.47269  -18.32516 1.000 55.53894 ? 205  ARG B NH1 1 
ATOM   4996 N  NH2 . ARG B  1 174 ? 39.02508 31.59167  -17.33210 1.000 51.53974 ? 205  ARG B NH2 1 
ATOM   4997 N  N   . ASP B  1 175 ? 40.31713 37.23910  -18.38158 1.000 29.17809 ? 206  ASP B N   1 
ATOM   4998 C  CA  . ASP B  1 175 ? 39.65093 38.38801  -17.78505 1.000 26.91692 ? 206  ASP B CA  1 
ATOM   4999 C  C   . ASP B  1 175 ? 39.51426 38.26246  -16.26895 1.000 26.08370 ? 206  ASP B C   1 
ATOM   5000 O  O   . ASP B  1 175 ? 39.20103 39.26366  -15.61582 1.000 26.51897 ? 206  ASP B O   1 
ATOM   5001 C  CB  . ASP B  1 175 ? 38.28661 38.65835  -18.45627 1.000 26.42945 ? 206  ASP B CB  1 
ATOM   5002 C  CG  . ASP B  1 175 ? 37.35605 37.43974  -18.49533 1.000 27.61377 ? 206  ASP B CG  1 
ATOM   5003 O  OD1 . ASP B  1 175 ? 37.59899 36.45523  -17.77155 1.000 29.35805 ? 206  ASP B OD1 1 
ATOM   5004 O  OD2 . ASP B  1 175 ? 36.36100 37.48123  -19.26811 1.000 27.32014 ? 206  ASP B OD2 1 
ATOM   5005 N  N   . TYR B  1 176 ? 39.79487 37.08539  -15.69184 1.000 24.69289 ? 207  TYR B N   1 
ATOM   5006 C  CA  . TYR B  1 176 ? 39.76119 36.92817  -14.23755 1.000 24.05259 ? 207  TYR B CA  1 
ATOM   5007 C  C   . TYR B  1 176 ? 40.82372 37.75875  -13.53266 1.000 24.60283 ? 207  TYR B C   1 
ATOM   5008 O  O   . TYR B  1 176 ? 40.71828 37.98298  -12.32257 1.000 22.03021 ? 207  TYR B O   1 
ATOM   5009 C  CB  . TYR B  1 176 ? 39.94297 35.45993  -13.84561 1.000 23.79713 ? 207  TYR B CB  1 
ATOM   5010 C  CG  . TYR B  1 176 ? 38.66070 34.65598  -13.75587 1.000 24.70598 ? 207  TYR B CG  1 
ATOM   5011 C  CD1 . TYR B  1 176 ? 37.74220 34.64874  -14.80055 1.000 25.40696 ? 207  TYR B CD1 1 
ATOM   5012 C  CD2 . TYR B  1 176 ? 38.38252 33.88403  -12.63169 1.000 26.38403 ? 207  TYR B CD2 1 
ATOM   5013 C  CE1 . TYR B  1 176 ? 36.57477 33.90425  -14.72076 1.000 24.78514 ? 207  TYR B CE1 1 
ATOM   5014 C  CE2 . TYR B  1 176 ? 37.21809 33.13452  -12.54700 1.000 22.24915 ? 207  TYR B CE2 1 
ATOM   5015 C  CZ  . TYR B  1 176 ? 36.32455 33.14880  -13.59002 1.000 26.17626 ? 207  TYR B CZ  1 
ATOM   5016 O  OH  . TYR B  1 176 ? 35.16545 32.40359  -13.49189 1.000 24.33375 ? 207  TYR B OH  1 
ATOM   5017 N  N   . VAL B  1 177 ? 41.85759 38.20875  -14.24189 1.000 24.35323 ? 208  VAL B N   1 
ATOM   5018 C  CA  . VAL B  1 177 ? 42.88112 39.04104  -13.62243 1.000 23.83100 ? 208  VAL B CA  1 
ATOM   5019 C  C   . VAL B  1 177 ? 42.87367 40.46907  -14.14483 1.000 24.84885 ? 208  VAL B C   1 
ATOM   5020 O  O   . VAL B  1 177 ? 43.72407 41.26302  -13.72412 1.000 26.88162 ? 208  VAL B O   1 
ATOM   5021 C  CB  . VAL B  1 177 ? 44.28711 38.42026  -13.77453 1.000 25.75615 ? 208  VAL B CB  1 
ATOM   5022 C  CG1 . VAL B  1 177 ? 44.31022 36.98725  -13.20693 1.000 23.56307 ? 208  VAL B CG1 1 
ATOM   5023 C  CG2 . VAL B  1 177 ? 44.73458 38.45029  -15.22972 1.000 26.36663 ? 208  VAL B CG2 1 
ATOM   5024 N  N   . PHE B  1 178 ? 41.94373 40.82776  -15.03423 1.000 24.15895 ? 209  PHE B N   1 
ATOM   5025 C  CA  . PHE B  1 178 ? 41.85306 42.20848  -15.50185 1.000 24.64610 ? 209  PHE B CA  1 
ATOM   5026 C  C   . PHE B  1 178 ? 41.59940 43.14334  -14.32058 1.000 28.84622 ? 209  PHE B C   1 
ATOM   5027 O  O   . PHE B  1 178 ? 40.90548 42.78048  -13.36539 1.000 26.23733 ? 209  PHE B O   1 
ATOM   5028 C  CB  . PHE B  1 178 ? 40.70251 42.40023  -16.49532 1.000 29.31672 ? 209  PHE B CB  1 
ATOM   5029 C  CG  . PHE B  1 178 ? 40.92730 41.81616  -17.86109 1.000 31.39019 ? 209  PHE B CG  1 
ATOM   5030 C  CD1 . PHE B  1 178 ? 42.11761 41.19912  -18.20419 1.000 30.52495 ? 209  PHE B CD1 1 
ATOM   5031 C  CD2 . PHE B  1 178 ? 39.91715 41.90011  -18.81598 1.000 30.40031 ? 209  PHE B CD2 1 
ATOM   5032 C  CE1 . PHE B  1 178 ? 42.29434 40.66242  -19.47812 1.000 34.49648 ? 209  PHE B CE1 1 
ATOM   5033 C  CE2 . PHE B  1 178 ? 40.08533 41.36712  -20.08907 1.000 31.15616 ? 209  PHE B CE2 1 
ATOM   5034 C  CZ  . PHE B  1 178 ? 41.27587 40.75179  -20.42111 1.000 32.19759 ? 209  PHE B CZ  1 
ATOM   5035 N  N   . PRO B  1 179 ? 42.11162 44.36740  -14.37025 1.000 28.18863 ? 210  PRO B N   1 
ATOM   5036 C  CA  . PRO B  1 179 ? 41.71581 45.35042  -13.35992 1.000 25.62413 ? 210  PRO B CA  1 
ATOM   5037 C  C   . PRO B  1 179 ? 40.20706 45.55248  -13.37796 1.000 22.74235 ? 210  PRO B C   1 
ATOM   5038 O  O   . PRO B  1 179 ? 39.57941 45.57779  -14.43739 1.000 25.17795 ? 210  PRO B O   1 
ATOM   5039 C  CB  . PRO B  1 179 ? 42.45803 46.62661  -13.78683 1.000 28.30737 ? 210  PRO B CB  1 
ATOM   5040 C  CG  . PRO B  1 179 ? 43.57168 46.14583  -14.68883 1.000 29.23421 ? 210  PRO B CG  1 
ATOM   5041 C  CD  . PRO B  1 179 ? 43.02141 44.93108  -15.38238 1.000 29.81421 ? 210  PRO B CD  1 
ATOM   5042 N  N   . MET B  1 180 ? 39.62494 45.68639  -12.19104 1.000 23.08695 ? 211  MET B N   1 
ATOM   5043 C  CA  . MET B  1 180 ? 38.21988 46.04551  -12.09272 1.000 24.27107 ? 211  MET B CA  1 
ATOM   5044 C  C   . MET B  1 180 ? 38.04151 47.52584  -12.42000 1.000 26.90177 ? 211  MET B C   1 
ATOM   5045 O  O   . MET B  1 180 ? 39.00997 48.27014  -12.59710 1.000 25.93861 ? 211  MET B O   1 
ATOM   5046 C  CB  . MET B  1 180 ? 37.69412 45.71872  -10.69986 1.000 21.36902 ? 211  MET B CB  1 
ATOM   5047 C  CG  . MET B  1 180 ? 37.77250 44.22572  -10.37885 1.000 21.13070 ? 211  MET B CG  1 
ATOM   5048 S  SD  . MET B  1 180 ? 36.77074 43.74535  -8.94945  1.000 23.29672 ? 211  MET B SD  1 
ATOM   5049 C  CE  . MET B  1 180 ? 37.54771 44.69553  -7.64282  1.000 21.79854 ? 211  MET B CE  1 
ATOM   5050 N  N   . GLU B  1 181 ? 36.78433 47.96365  -12.50071 1.000 20.84600 ? 212  GLU B N   1 
ATOM   5051 C  CA  . GLU B  1 181 ? 36.50538 49.32182  -12.94139 1.000 20.17484 ? 212  GLU B CA  1 
ATOM   5052 C  C   . GLU B  1 181 ? 35.49174 49.98826  -12.03286 1.000 25.61743 ? 212  GLU B C   1 
ATOM   5053 O  O   . GLU B  1 181 ? 34.72370 49.33377  -11.32652 1.000 23.76642 ? 212  GLU B O   1 
ATOM   5054 C  CB  . GLU B  1 181 ? 35.98457 49.37051  -14.37751 1.000 25.97403 ? 212  GLU B CB  1 
ATOM   5055 C  CG  . GLU B  1 181 ? 34.64898 48.65865  -14.58322 1.000 24.24260 ? 212  GLU B CG  1 
ATOM   5056 C  CD  . GLU B  1 181 ? 33.94973 49.10802  -15.85027 1.000 22.42987 ? 212  GLU B CD  1 
ATOM   5057 O  OE1 . GLU B  1 181 ? 33.23130 50.12663  -15.81652 1.000 25.72986 ? 212  GLU B OE1 1 
ATOM   5058 O  OE2 . GLU B  1 181 ? 34.13291 48.45121  -16.89143 1.000 24.60207 ? 212  GLU B OE2 1 
ATOM   5059 N  N   . HIS B  1 182 ? 35.51229 51.31804  -12.07107 1.000 22.62609 ? 213  HIS B N   1 
ATOM   5060 C  CA  . HIS B  1 182 ? 34.50783 52.15576  -11.43061 1.000 22.71549 ? 213  HIS B CA  1 
ATOM   5061 C  C   . HIS B  1 182 ? 34.03474 53.14349  -12.48394 1.000 24.71826 ? 213  HIS B C   1 
ATOM   5062 O  O   . HIS B  1 182 ? 34.76609 54.07810  -12.81912 1.000 24.18263 ? 213  HIS B O   1 
ATOM   5063 C  CB  . HIS B  1 182 ? 35.08479 52.88450  -10.21807 1.000 22.65296 ? 213  HIS B CB  1 
ATOM   5064 C  CG  . HIS B  1 182 ? 34.08403 53.73766  -9.50647  1.000 25.71800 ? 213  HIS B CG  1 
ATOM   5065 N  ND1 . HIS B  1 182 ? 34.43905 54.83698  -8.75640  1.000 35.89243 ? 213  HIS B ND1 1 
ATOM   5066 C  CD2 . HIS B  1 182 ? 32.73521 53.64306  -9.42457  1.000 23.70313 ? 213  HIS B CD2 1 
ATOM   5067 C  CE1 . HIS B  1 182 ? 33.35067 55.38641  -8.24555  1.000 34.84319 ? 213  HIS B CE1 1 
ATOM   5068 N  NE2 . HIS B  1 182 ? 32.30475 54.67698  -8.63155  1.000 29.95542 ? 213  HIS B NE2 1 
ATOM   5069 N  N   . ASN B  1 183 ? 32.83400 52.93023  -13.02093 1.000 22.97799 ? 214  ASN B N   1 
ATOM   5070 C  CA  . ASN B  1 183 ? 32.27468 53.78532  -14.07744 1.000 24.02720 ? 214  ASN B CA  1 
ATOM   5071 C  C   . ASN B  1 183 ? 33.26436 53.98210  -15.22800 1.000 29.32482 ? 214  ASN B C   1 
ATOM   5072 O  O   . ASN B  1 183 ? 33.50505 55.10096  -15.69286 1.000 27.71895 ? 214  ASN B O   1 
ATOM   5073 C  CB  . ASN B  1 183 ? 31.83099 55.13802  -13.51287 1.000 24.02909 ? 214  ASN B CB  1 
ATOM   5074 C  CG  . ASN B  1 183 ? 30.75668 55.00400  -12.45405 1.000 28.84825 ? 214  ASN B CG  1 
ATOM   5075 O  OD1 . ASN B  1 183 ? 29.89004 54.13593  -12.54308 1.000 24.95506 ? 214  ASN B OD1 1 
ATOM   5076 N  ND2 . ASN B  1 183 ? 30.80821 55.86403  -11.44641 1.000 28.50811 ? 214  ASN B ND2 1 
ATOM   5077 N  N   . GLY B  1 184 ? 33.84382 52.87529  -15.69187 1.000 28.36889 ? 215  GLY B N   1 
ATOM   5078 C  CA  . GLY B  1 184 ? 34.75583 52.90346  -16.81543 1.000 28.08728 ? 215  GLY B CA  1 
ATOM   5079 C  C   . GLY B  1 184 ? 36.18971 53.26841  -16.49033 1.000 31.15307 ? 215  GLY B C   1 
ATOM   5080 O  O   . GLY B  1 184 ? 37.04672 53.17622  -17.37878 1.000 34.60062 ? 215  GLY B O   1 
ATOM   5081 N  N   . LYS B  1 185 ? 36.48537 53.68137  -15.26078 1.000 27.42712 ? 216  LYS B N   1 
ATOM   5082 C  CA  . LYS B  1 185 ? 37.83612 54.02223  -14.82636 1.000 30.23410 ? 216  LYS B CA  1 
ATOM   5083 C  C   . LYS B  1 185 ? 38.43060 52.90016  -13.98715 1.000 31.22083 ? 216  LYS B C   1 
ATOM   5084 O  O   . LYS B  1 185 ? 37.70140 52.08144  -13.42363 1.000 26.30944 ? 216  LYS B O   1 
ATOM   5085 C  CB  . LYS B  1 185 ? 37.81948 55.31449  -14.00350 1.000 32.44444 ? 216  LYS B CB  1 
ATOM   5086 C  CG  . LYS B  1 185 ? 37.02590 56.45465  -14.62027 1.000 41.64916 ? 216  LYS B CG  1 
ATOM   5087 C  CD  . LYS B  1 185 ? 37.65446 56.95939  -15.90130 1.000 41.73413 ? 216  LYS B CD  1 
ATOM   5088 C  CE  . LYS B  1 185 ? 37.55719 58.47934  -15.97561 1.000 54.98435 ? 216  LYS B CE  1 
ATOM   5089 N  NZ  . LYS B  1 185 ? 36.35806 58.99841  -15.24564 1.000 55.75271 ? 216  LYS B NZ  1 
ATOM   5090 N  N   . PRO B  1 186 ? 39.75776 52.83214  -13.86595 1.000 31.89478 ? 217  PRO B N   1 
ATOM   5091 C  CA  . PRO B  1 186 ? 40.36269 51.79104  -13.02108 1.000 33.57947 ? 217  PRO B CA  1 
ATOM   5092 C  C   . PRO B  1 186 ? 39.85521 51.86197  -11.58582 1.000 31.52425 ? 217  PRO B C   1 
ATOM   5093 O  O   . PRO B  1 186 ? 39.74214 52.94067  -11.00141 1.000 33.33827 ? 217  PRO B O   1 
ATOM   5094 C  CB  . PRO B  1 186 ? 41.86415 52.10100  -13.10062 1.000 36.57128 ? 217  PRO B CB  1 
ATOM   5095 C  CG  . PRO B  1 186 ? 42.03004 52.80089  -14.41407 1.000 31.91134 ? 217  PRO B CG  1 
ATOM   5096 C  CD  . PRO B  1 186 ? 40.77770 53.61870  -14.59182 1.000 32.26515 ? 217  PRO B CD  1 
ATOM   5097 N  N   . ALA B  1 187 ? 39.54080 50.69197  -11.01549 1.000 26.62083 ? 218  ALA B N   1 
ATOM   5098 C  CA  . ALA B  1 187 ? 39.02702 50.66271  -9.64751  1.000 25.34342 ? 218  ALA B CA  1 
ATOM   5099 C  C   . ALA B  1 187 ? 40.12649 50.81187  -8.60219  1.000 28.91660 ? 218  ALA B C   1 
ATOM   5100 O  O   . ALA B  1 187 ? 39.86013 51.31790  -7.50644  1.000 29.21174 ? 218  ALA B O   1 
ATOM   5101 C  CB  . ALA B  1 187 ? 38.25479 49.36375  -9.39079  1.000 25.52172 ? 218  ALA B CB  1 
ATOM   5102 N  N   . ASN B  1 188 ? 41.34644 50.36723  -8.90660  1.000 27.65222 ? 219  ASN B N   1 
ATOM   5103 C  CA  . ASN B  1 188 ? 42.45826 50.38156  -7.95107  1.000 28.88063 ? 219  ASN B CA  1 
ATOM   5104 C  C   . ASN B  1 188 ? 42.07091 49.71126  -6.63397  1.000 26.22705 ? 219  ASN B C   1 
ATOM   5105 O  O   . ASN B  1 188 ? 42.31153 50.23256  -5.54417  1.000 28.51894 ? 219  ASN B O   1 
ATOM   5106 C  CB  . ASN B  1 188 ? 42.95560 51.80865  -7.70579  1.000 31.91164 ? 219  ASN B CB  1 
ATOM   5107 C  CG  . ASN B  1 188 ? 43.41859 52.49255  -8.98056  1.000 37.06129 ? 219  ASN B CG  1 
ATOM   5108 O  OD1 . ASN B  1 188 ? 43.01151 53.61615  -9.28206  1.000 42.13793 ? 219  ASN B OD1 1 
ATOM   5109 N  ND2 . ASN B  1 188 ? 44.26938 51.81564  -9.73527  1.000 32.98928 ? 219  ASN B ND2 1 
ATOM   5110 N  N   . GLU B  1 189 ? 41.44786 48.53981  -6.74145  1.000 23.68315 ? 220  GLU B N   1 
ATOM   5111 C  CA  . GLU B  1 189 ? 41.01737 47.82925  -5.54440  1.000 24.65025 ? 220  GLU B CA  1 
ATOM   5112 C  C   . GLU B  1 189 ? 42.22683 47.41866  -4.70997  1.000 24.73726 ? 220  GLU B C   1 
ATOM   5113 O  O   . GLU B  1 189 ? 43.26641 47.03215  -5.24698  1.000 26.86485 ? 220  GLU B O   1 
ATOM   5114 C  CB  . GLU B  1 189 ? 40.18621 46.59812  -5.93273  1.000 21.80953 ? 220  GLU B CB  1 
ATOM   5115 C  CG  . GLU B  1 189 ? 39.68280 45.78839  -4.73882  1.000 22.71157 ? 220  GLU B CG  1 
ATOM   5116 C  CD  . GLU B  1 189 ? 38.79436 46.60383  -3.81700  1.000 22.09991 ? 220  GLU B CD  1 
ATOM   5117 O  OE1 . GLU B  1 189 ? 37.68328 46.99893  -4.24158  1.000 25.51750 ? 220  GLU B OE1 1 
ATOM   5118 O  OE2 . GLU B  1 189 ? 39.19853 46.85087  -2.66382  1.000 23.79827 ? 220  GLU B OE2 1 
ATOM   5119 N  N   . THR B  1 190 ? 42.09204 47.52578  -3.38596  1.000 22.41434 ? 221  THR B N   1 
ATOM   5120 C  CA  . THR B  1 190 ? 43.14862 47.13336  -2.46119  1.000 24.55856 ? 221  THR B CA  1 
ATOM   5121 C  C   . THR B  1 190 ? 42.74317 46.03560  -1.49074  1.000 26.72436 ? 221  THR B C   1 
ATOM   5122 O  O   . THR B  1 190 ? 43.60662 45.52564  -0.76650  1.000 28.05667 ? 221  THR B O   1 
ATOM   5123 C  CB  . THR B  1 190 ? 43.62406 48.34459  -1.64572  1.000 29.42017 ? 221  THR B CB  1 
ATOM   5124 O  OG1 . THR B  1 190 ? 42.53013 48.85965  -0.87691  1.000 30.42074 ? 221  THR B OG1 1 
ATOM   5125 C  CG2 . THR B  1 190 ? 44.13989 49.44568  -2.57032  1.000 30.80511 ? 221  THR B CG2 1 
ATOM   5126 N  N   . GLU B  1 191 ? 41.46947 45.66393  -1.43884  1.000 24.05952 ? 222  GLU B N   1 
ATOM   5127 C  CA  . GLU B  1 191 ? 40.99546 44.66526  -0.49790  1.000 24.07676 ? 222  GLU B CA  1 
ATOM   5128 C  C   . GLU B  1 191 ? 40.60365 43.39454  -1.23722  1.000 18.65953 ? 222  GLU B C   1 
ATOM   5129 O  O   . GLU B  1 191 ? 40.30500 43.41355  -2.43297  1.000 22.35126 ? 222  GLU B O   1 
ATOM   5130 C  CB  . GLU B  1 191 ? 39.79024 45.18567  0.29983   1.000 25.63478 ? 222  GLU B CB  1 
ATOM   5131 C  CG  . GLU B  1 191 ? 40.02985 46.52400  0.98708   1.000 23.96777 ? 222  GLU B CG  1 
ATOM   5132 C  CD  . GLU B  1 191 ? 38.90482 46.91438  1.93007   1.000 29.98136 ? 222  GLU B CD  1 
ATOM   5133 O  OE1 . GLU B  1 191 ? 38.60909 46.13813  2.86002   1.000 30.00183 ? 222  GLU B OE1 1 
ATOM   5134 O  OE2 . GLU B  1 191 ? 38.32595 48.00813  1.74790   1.000 30.08705 ? 222  GLU B OE2 1 
ATOM   5135 N  N   . TYR B  1 192 ? 40.64418 42.28041  -0.51224  1.000 18.73598 ? 223  TYR B N   1 
ATOM   5136 C  CA  . TYR B  1 192 ? 39.87898 41.09768  -0.89764  1.000 19.39257 ? 223  TYR B CA  1 
ATOM   5137 C  C   . TYR B  1 192 ? 38.54056 41.53385  -1.48233  1.000 19.87536 ? 223  TYR B C   1 
ATOM   5138 O  O   . TYR B  1 192 ? 37.81083 42.31312  -0.85829  1.000 21.69798 ? 223  TYR B O   1 
ATOM   5139 C  CB  . TYR B  1 192 ? 39.67361 40.23362  0.34439   1.000 19.29581 ? 223  TYR B CB  1 
ATOM   5140 C  CG  . TYR B  1 192 ? 38.96348 38.92231  0.15332   1.000 19.61461 ? 223  TYR B CG  1 
ATOM   5141 C  CD1 . TYR B  1 192 ? 39.57657 37.86621  -0.51614  1.000 19.50070 ? 223  TYR B CD1 1 
ATOM   5142 C  CD2 . TYR B  1 192 ? 37.70245 38.71134  0.70199   1.000 17.59319 ? 223  TYR B CD2 1 
ATOM   5143 C  CE1 . TYR B  1 192 ? 38.93436 36.63700  -0.66075  1.000 21.70535 ? 223  TYR B CE1 1 
ATOM   5144 C  CE2 . TYR B  1 192 ? 37.05465 37.48269  0.56737   1.000 18.75625 ? 223  TYR B CE2 1 
ATOM   5145 C  CZ  . TYR B  1 192 ? 37.67538 36.45409  -0.11908  1.000 19.11465 ? 223  TYR B CZ  1 
ATOM   5146 O  OH  . TYR B  1 192 ? 37.04148 35.22972  -0.25701  1.000 19.73414 ? 223  TYR B OH  1 
ATOM   5147 N  N   . ILE B  1 193 ? 38.23841 41.09838  -2.71196  1.000 19.42936 ? 224  ILE B N   1 
ATOM   5148 C  CA  . ILE B  1 193 ? 37.25173 41.86138  -3.47918  1.000 19.15031 ? 224  ILE B CA  1 
ATOM   5149 C  C   . ILE B  1 193 ? 35.85659 41.74074  -2.87488  1.000 17.81221 ? 224  ILE B C   1 
ATOM   5150 O  O   . ILE B  1 193 ? 35.04414 42.65821  -3.02840  1.000 19.90444 ? 224  ILE B O   1 
ATOM   5151 C  CB  . ILE B  1 193 ? 37.23769 41.50063  -4.97814  1.000 19.90728 ? 224  ILE B CB  1 
ATOM   5152 C  CG1 . ILE B  1 193 ? 36.74833 40.06683  -5.24015  1.000 19.06532 ? 224  ILE B CG1 1 
ATOM   5153 C  CG2 . ILE B  1 193 ? 38.60385 41.79010  -5.61585  1.000 22.20291 ? 224  ILE B CG2 1 
ATOM   5154 C  CD1 . ILE B  1 193 ? 36.57574 39.80430  -6.73273  1.000 20.12378 ? 224  ILE B CD1 1 
ATOM   5155 N  N   . THR B  1 194 ? 35.55973 40.65503  -2.15287  1.000 18.84086 ? 225  THR B N   1 
ATOM   5156 C  CA  . THR B  1 194 ? 34.29212 40.61157  -1.41922  1.000 17.70413 ? 225  THR B CA  1 
ATOM   5157 C  C   . THR B  1 194 ? 34.19417 41.77088  -0.42763  1.000 20.65717 ? 225  THR B C   1 
ATOM   5158 O  O   . THR B  1 194 ? 33.15034 42.43181  -0.32886  1.000 18.79496 ? 225  THR B O   1 
ATOM   5159 C  CB  . THR B  1 194 ? 34.14086 39.26697  -0.70269  1.000 17.08360 ? 225  THR B CB  1 
ATOM   5160 O  OG1 . THR B  1 194 ? 34.21857 38.20524  -1.66551  1.000 17.91385 ? 225  THR B OG1 1 
ATOM   5161 C  CG2 . THR B  1 194 ? 32.78564 39.17970  0.01015   1.000 18.94553 ? 225  THR B CG2 1 
ATOM   5162 N  N   . ASP B  1 195 ? 35.27655 42.03791  0.31000   1.000 19.21661 ? 226  ASP B N   1 
ATOM   5163 C  CA  . ASP B  1 195 ? 35.29317 43.18582  1.21367   1.000 21.91216 ? 226  ASP B CA  1 
ATOM   5164 C  C   . ASP B  1 195 ? 35.18578 44.49314  0.43916   1.000 20.57273 ? 226  ASP B C   1 
ATOM   5165 O  O   . ASP B  1 195 ? 34.52255 45.43633  0.88886   1.000 20.32434 ? 226  ASP B O   1 
ATOM   5166 C  CB  . ASP B  1 195 ? 36.57105 43.18893  2.05852   1.000 21.03242 ? 226  ASP B CB  1 
ATOM   5167 C  CG  . ASP B  1 195 ? 36.68111 41.99264  2.99633   1.000 24.99577 ? 226  ASP B CG  1 
ATOM   5168 O  OD1 . ASP B  1 195 ? 35.66505 41.34181  3.30034   1.000 23.68390 ? 226  ASP B OD1 1 
ATOM   5169 O  OD2 . ASP B  1 195 ? 37.81157 41.72043  3.45443   1.000 24.70922 ? 226  ASP B OD2 1 
ATOM   5170 N  N   . GLY B  1 196 ? 35.84538 44.57466  -0.72085  1.000 19.33727 ? 227  GLY B N   1 
ATOM   5171 C  CA  . GLY B  1 196 ? 35.72701 45.77174  -1.54286  1.000 18.57786 ? 227  GLY B CA  1 
ATOM   5172 C  C   . GLY B  1 196 ? 34.30638 46.00577  -2.02559  1.000 19.28771 ? 227  GLY B C   1 
ATOM   5173 O  O   . GLY B  1 196 ? 33.80722 47.13453  -1.99926  1.000 20.82368 ? 227  GLY B O   1 
ATOM   5174 N  N   . PHE B  1 197 ? 33.62956 44.94199  -2.45905  1.000 18.36320 ? 228  PHE B N   1 
ATOM   5175 C  CA  . PHE B  1 197 ? 32.24328 45.10382  -2.88672  1.000 18.32945 ? 228  PHE B CA  1 
ATOM   5176 C  C   . PHE B  1 197 ? 31.35317 45.54261  -1.72694  1.000 19.12892 ? 228  PHE B C   1 
ATOM   5177 O  O   . PHE B  1 197 ? 30.45948 46.38499  -1.90403  1.000 19.11625 ? 228  PHE B O   1 
ATOM   5178 C  CB  . PHE B  1 197 ? 31.73553 43.80706  -3.50926  1.000 16.57752 ? 228  PHE B CB  1 
ATOM   5179 C  CG  . PHE B  1 197 ? 32.47883 43.39152  -4.75476  1.000 18.96870 ? 228  PHE B CG  1 
ATOM   5180 C  CD1 . PHE B  1 197 ? 33.05742 44.33214  -5.59001  1.000 19.90302 ? 228  PHE B CD1 1 
ATOM   5181 C  CD2 . PHE B  1 197 ? 32.59659 42.04189  -5.08263  1.000 18.72222 ? 228  PHE B CD2 1 
ATOM   5182 C  CE1 . PHE B  1 197 ? 33.75132 43.93487  -6.73894  1.000 19.66882 ? 228  PHE B CE1 1 
ATOM   5183 C  CE2 . PHE B  1 197 ? 33.28119 41.63149  -6.22424  1.000 19.04940 ? 228  PHE B CE2 1 
ATOM   5184 C  CZ  . PHE B  1 197 ? 33.86730 42.58243  -7.05050  1.000 20.34579 ? 228  PHE B CZ  1 
ATOM   5185 N  N   . SER B  1 198 ? 31.58005 44.98475  -0.53200  1.000 16.73604 ? 229  SER B N   1 
ATOM   5186 C  CA  . SER B  1 198 ? 30.80877 45.40465  0.64075   1.000 18.07774 ? 229  SER B CA  1 
ATOM   5187 C  C   . SER B  1 198 ? 31.05174 46.87591  0.94172   1.000 20.14850 ? 229  SER B C   1 
ATOM   5188 O  O   . SER B  1 198 ? 30.11294 47.62816  1.23280   1.000 19.39939 ? 229  SER B O   1 
ATOM   5189 C  CB  . SER B  1 198 ? 31.17771 44.54843  1.85346   1.000 18.57982 ? 229  SER B CB  1 
ATOM   5190 O  OG  . SER B  1 198 ? 30.91622 43.17951  1.61354   1.000 17.91096 ? 229  SER B OG  1 
ATOM   5191 N  N   . ARG B  1 199 ? 32.31560 47.30017  0.85979   1.000 20.39238 ? 230  ARG B N   1 
ATOM   5192 C  CA  . ARG B  1 199 ? 32.66732 48.70076  1.07019   1.000 21.51122 ? 230  ARG B CA  1 
ATOM   5193 C  C   . ARG B  1 199 ? 31.93105 49.60909  0.09256   1.000 19.92282 ? 230  ARG B C   1 
ATOM   5194 O  O   . ARG B  1 199 ? 31.39848 50.65616  0.48459   1.000 21.15597 ? 230  ARG B O   1 
ATOM   5195 C  CB  . ARG B  1 199 ? 34.18236 48.86257  0.93127   1.000 23.26470 ? 230  ARG B CB  1 
ATOM   5196 C  CG  . ARG B  1 199 ? 34.70975 50.26980  1.15826   1.000 21.86853 ? 230  ARG B CG  1 
ATOM   5197 C  CD  . ARG B  1 199 ? 36.11228 50.41682  0.56287   1.000 25.10006 ? 230  ARG B CD  1 
ATOM   5198 N  NE  . ARG B  1 199 ? 36.11556 50.27991  -0.89032  1.000 21.97447 ? 230  ARG B NE  1 
ATOM   5199 C  CZ  . ARG B  1 199 ? 36.84023 49.39541  -1.56548  1.000 23.89858 ? 230  ARG B CZ  1 
ATOM   5200 N  NH1 . ARG B  1 199 ? 37.67009 48.56254  -0.95165  1.000 22.72303 ? 230  ARG B NH1 1 
ATOM   5201 N  NH2 . ARG B  1 199 ? 36.74414 49.35457  -2.89311  1.000 23.03401 ? 230  ARG B NH2 1 
ATOM   5202 N  N   . GLU B  1 200 ? 31.86715 49.21267  -1.17949  1.000 19.21618 ? 231  GLU B N   1 
ATOM   5203 C  CA  . GLU B  1 200 ? 31.21171 50.04347  -2.18062  1.000 19.47094 ? 231  GLU B CA  1 
ATOM   5204 C  C   . GLU B  1 200 ? 29.70381 50.07406  -1.97640  1.000 21.85932 ? 231  GLU B C   1 
ATOM   5205 O  O   . GLU B  1 200 ? 29.05979 51.09286  -2.26722  1.000 19.64466 ? 231  GLU B O   1 
ATOM   5206 C  CB  . GLU B  1 200 ? 31.56959 49.55063  -3.58484  1.000 20.96545 ? 231  GLU B CB  1 
ATOM   5207 C  CG  . GLU B  1 200 ? 33.06576 49.71720  -3.91044  1.000 21.64235 ? 231  GLU B CG  1 
ATOM   5208 C  CD  . GLU B  1 200 ? 33.53182 51.16935  -3.81311  1.000 26.10623 ? 231  GLU B CD  1 
ATOM   5209 O  OE1 . GLU B  1 200 ? 32.82058 52.06028  -4.32926  1.000 23.52532 ? 231  GLU B OE1 1 
ATOM   5210 O  OE2 . GLU B  1 200 ? 34.60371 51.41185  -3.21050  1.000 24.42370 ? 231  GLU B OE2 1 
ATOM   5211 N  N   . ALA B  1 201 ? 29.12760 48.98202  -1.46031  1.000 18.53202 ? 232  ALA B N   1 
ATOM   5212 C  CA  . ALA B  1 201 ? 27.70156 48.99262  -1.15416  1.000 18.50398 ? 232  ALA B CA  1 
ATOM   5213 C  C   . ALA B  1 201 ? 27.40199 49.98012  -0.03972  1.000 20.99288 ? 232  ALA B C   1 
ATOM   5214 O  O   . ALA B  1 201 ? 26.42201 50.73536  -0.11314  1.000 19.89723 ? 232  ALA B O   1 
ATOM   5215 C  CB  . ALA B  1 201 ? 27.22552 47.58656  -0.77560  1.000 18.61393 ? 232  ALA B CB  1 
ATOM   5216 N  N   . ILE B  1 202 ? 28.24580 49.98939  0.99408   1.000 19.44847 ? 233  ILE B N   1 
ATOM   5217 C  CA  . ILE B  1 202 ? 28.10499 50.95002  2.08189   1.000 19.19000 ? 233  ILE B CA  1 
ATOM   5218 C  C   . ILE B  1 202 ? 28.20633 52.37617  1.55061   1.000 21.56951 ? 233  ILE B C   1 
ATOM   5219 O  O   . ILE B  1 202 ? 27.40133 53.24552  1.90607   1.000 20.72109 ? 233  ILE B O   1 
ATOM   5220 C  CB  . ILE B  1 202 ? 29.15836 50.65814  3.16386   1.000 20.86378 ? 233  ILE B CB  1 
ATOM   5221 C  CG1 . ILE B  1 202 ? 28.80359 49.36206  3.90283   1.000 19.40574 ? 233  ILE B CG1 1 
ATOM   5222 C  CG2 . ILE B  1 202 ? 29.29671 51.83438  4.12962   1.000 21.86547 ? 233  ILE B CG2 1 
ATOM   5223 C  CD1 . ILE B  1 202 ? 29.98259 48.71399  4.60556   1.000 22.22065 ? 233  ILE B CD1 1 
ATOM   5224 N  N   . LYS B  1 203 ? 29.18115 52.63386  0.67792   1.000 20.48757 ? 234  LYS B N   1 
ATOM   5225 C  CA  . LYS B  1 203 ? 29.33361 53.97027  0.10871   1.000 23.23865 ? 234  LYS B CA  1 
ATOM   5226 C  C   . LYS B  1 203 ? 28.08072 54.38955  -0.64876  1.000 22.55804 ? 234  LYS B C   1 
ATOM   5227 O  O   . LYS B  1 203 ? 27.57188 55.50356  -0.46862  1.000 20.72775 ? 234  LYS B O   1 
ATOM   5228 C  CB  . LYS B  1 203 ? 30.55281 54.01756  -0.81263  1.000 20.81197 ? 234  LYS B CB  1 
ATOM   5229 C  CG  . LYS B  1 203 ? 30.78156 55.39422  -1.43808  1.000 24.16807 ? 234  LYS B CG  1 
ATOM   5230 C  CD  . LYS B  1 203 ? 31.89717 55.36705  -2.47443  1.000 27.68971 ? 234  LYS B CD  1 
ATOM   5231 C  CE  . LYS B  1 203 ? 32.28203 56.78937  -2.87615  1.000 30.59739 ? 234  LYS B CE  1 
ATOM   5232 N  NZ  . LYS B  1 203 ? 33.31836 56.81306  -3.94514  1.000 35.50081 ? 234  LYS B NZ  1 
ATOM   5233 N  N   . ASN B  1 204 ? 27.54892 53.49547  -1.48680  1.000 19.70125 ? 235  ASN B N   1 
ATOM   5234 C  CA  . ASN B  1 204 ? 26.39747 53.86490  -2.30263  1.000 20.53306 ? 235  ASN B CA  1 
ATOM   5235 C  C   . ASN B  1 204 ? 25.12911 54.04027  -1.47033  1.000 22.32489 ? 235  ASN B C   1 
ATOM   5236 O  O   . ASN B  1 204 ? 24.28428 54.87807  -1.81638  1.000 21.42147 ? 235  ASN B O   1 
ATOM   5237 C  CB  . ASN B  1 204 ? 26.21389 52.83575  -3.41961  1.000 21.20271 ? 235  ASN B CB  1 
ATOM   5238 C  CG  . ASN B  1 204 ? 27.15753 53.09651  -4.57625  1.000 26.78631 ? 235  ASN B CG  1 
ATOM   5239 O  OD1 . ASN B  1 204 ? 26.86525 53.90098  -5.46613  1.000 28.57847 ? 235  ASN B OD1 1 
ATOM   5240 N  ND2 . ASN B  1 204 ? 28.31202 52.46033  -4.54707  1.000 27.79067 ? 235  ASN B ND2 1 
ATOM   5241 N  N   . ILE B  1 205 ? 24.98716 53.28903  -0.37314  1.000 19.44988 ? 236  ILE B N   1 
ATOM   5242 C  CA  . ILE B  1 205 ? 23.90236 53.54368  0.57752   1.000 20.05941 ? 236  ILE B CA  1 
ATOM   5243 C  C   . ILE B  1 205 ? 24.01222 54.95552  1.14280   1.000 23.05100 ? 236  ILE B C   1 
ATOM   5244 O  O   . ILE B  1 205 ? 23.01197 55.67741  1.25834   1.000 21.44736 ? 236  ILE B O   1 
ATOM   5245 C  CB  . ILE B  1 205 ? 23.91847 52.48763  1.70145   1.000 19.44548 ? 236  ILE B CB  1 
ATOM   5246 C  CG1 . ILE B  1 205 ? 23.48069 51.11174  1.17169   1.000 20.00757 ? 236  ILE B CG1 1 
ATOM   5247 C  CG2 . ILE B  1 205 ? 23.06155 52.93999  2.87566   1.000 21.79962 ? 236  ILE B CG2 1 
ATOM   5248 C  CD1 . ILE B  1 205 ? 23.85090 49.95950  2.09740   1.000 18.94954 ? 236  ILE B CD1 1 
ATOM   5249 N  N   . LYS B  1 206 ? 25.22830 55.36716  1.51702   1.000 20.62911 ? 237  LYS B N   1 
ATOM   5250 C  CA  . LYS B  1 206 ? 25.41281 56.70573  2.06643   1.000 21.54124 ? 237  LYS B CA  1 
ATOM   5251 C  C   . LYS B  1 206 ? 25.17540 57.78344  1.01521   1.000 20.98201 ? 237  LYS B C   1 
ATOM   5252 O  O   . LYS B  1 206 ? 24.67090 58.86580  1.34628   1.000 19.21357 ? 237  LYS B O   1 
ATOM   5253 C  CB  . LYS B  1 206 ? 26.80994 56.82482  2.67234   1.000 21.58975 ? 237  LYS B CB  1 
ATOM   5254 C  CG  . LYS B  1 206 ? 26.99117 56.00342  3.94889   1.000 24.23208 ? 237  LYS B CG  1 
ATOM   5255 C  CD  . LYS B  1 206 ? 28.42510 56.07227  4.46155   1.000 27.78127 ? 237  LYS B CD  1 
ATOM   5256 C  CE  . LYS B  1 206 ? 28.61298 55.21015  5.69684   1.000 33.42511 ? 237  LYS B CE  1 
ATOM   5257 N  NZ  . LYS B  1 206 ? 30.02411 55.25063  6.19920   1.000 38.78789 ? 237  LYS B NZ  1 
ATOM   5258 N  N   . ILE B  1 207 ? 25.52238 57.51587  -0.24407  1.000 21.95867 ? 238  ILE B N   1 
ATOM   5259 C  CA  . ILE B  1 207 ? 25.25264 58.48357  -1.30568  1.000 20.68278 ? 238  ILE B CA  1 
ATOM   5260 C  C   . ILE B  1 207 ? 23.75338 58.69067  -1.45742  1.000 24.52584 ? 238  ILE B C   1 
ATOM   5261 O  O   . ILE B  1 207 ? 23.26389 59.82515  -1.53936  1.000 20.74262 ? 238  ILE B O   1 
ATOM   5262 C  CB  . ILE B  1 207 ? 25.89220 58.02574  -2.62844  1.000 23.02689 ? 238  ILE B CB  1 
ATOM   5263 C  CG1 . ILE B  1 207 ? 27.41936 58.10916  -2.52742  1.000 21.50620 ? 238  ILE B CG1 1 
ATOM   5264 C  CG2 . ILE B  1 207 ? 25.36321 58.86557  -3.78234  1.000 19.80815 ? 238  ILE B CG2 1 
ATOM   5265 C  CD1 . ILE B  1 207 ? 28.15385 57.45044  -3.67963  1.000 21.05312 ? 238  ILE B CD1 1 
ATOM   5266 N  N   . ALA B  1 208 ? 23.00010 57.59141  -1.50055  1.000 20.90341 ? 239  ALA B N   1 
ATOM   5267 C  CA  . ALA B  1 208 ? 21.55370 57.70453  -1.63585  1.000 22.64886 ? 239  ALA B CA  1 
ATOM   5268 C  C   . ALA B  1 208 ? 20.94718 58.41589  -0.43667  1.000 21.41075 ? 239  ALA B C   1 
ATOM   5269 O  O   . ALA B  1 208 ? 20.00919 59.20416  -0.58724  1.000 22.66143 ? 239  ALA B O   1 
ATOM   5270 C  CB  . ALA B  1 208 ? 20.93474 56.31675  -1.81090  1.000 23.23352 ? 239  ALA B CB  1 
ATOM   5271 N  N   . ALA B  1 209 ? 21.47730 58.16203  0.76292   1.000 20.12081 ? 240  ALA B N   1 
ATOM   5272 C  CA  . ALA B  1 209 ? 20.96587 58.85436  1.94130   1.000 22.54984 ? 240  ALA B CA  1 
ATOM   5273 C  C   . ALA B  1 209 ? 21.20695 60.35455  1.83881   1.000 23.59228 ? 240  ALA B C   1 
ATOM   5274 O  O   . ALA B  1 209 ? 20.33500 61.16005  2.19351   1.000 23.81629 ? 240  ALA B O   1 
ATOM   5275 C  CB  . ALA B  1 209 ? 21.60959 58.29599  3.20871   1.000 25.40084 ? 240  ALA B CB  1 
ATOM   5276 N  N   . ALA B  1 210 ? 22.37574 60.75056  1.33598   1.000 19.42229 ? 241  ALA B N   1 
ATOM   5277 C  CA  . ALA B  1 210 ? 22.65570 62.17314  1.18167   1.000 19.14432 ? 241  ALA B CA  1 
ATOM   5278 C  C   . ALA B  1 210 ? 21.79831 62.79003  0.08762   1.000 22.97160 ? 241  ALA B C   1 
ATOM   5279 O  O   . ALA B  1 210 ? 21.38277 63.94653  0.20617   1.000 24.12436 ? 241  ALA B O   1 
ATOM   5280 C  CB  . ALA B  1 210 ? 24.13824 62.39416  0.88870   1.000 20.73885 ? 241  ALA B CB  1 
ATOM   5281 N  N   . LYS B  1 211 ? 21.52002 62.03962  -0.97963  1.000 21.54696 ? 242  LYS B N   1 
ATOM   5282 C  CA  . LYS B  1 211 ? 20.65617 62.52866  -2.04922  1.000 23.16571 ? 242  LYS B CA  1 
ATOM   5283 C  C   . LYS B  1 211 ? 19.18772 62.56253  -1.64358  1.000 25.62935 ? 242  LYS B C   1 
ATOM   5284 O  O   . LYS B  1 211 ? 18.38168 63.19109  -2.33995  1.000 23.79028 ? 242  LYS B O   1 
ATOM   5285 C  CB  . LYS B  1 211 ? 20.81837 61.64999  -3.29695  1.000 23.93628 ? 242  LYS B CB  1 
ATOM   5286 C  CG  . LYS B  1 211 ? 22.15250 61.79415  -4.02691  1.000 22.66200 ? 242  LYS B CG  1 
ATOM   5287 C  CD  . LYS B  1 211 ? 22.26946 60.75064  -5.14495  1.000 25.88588 ? 242  LYS B CD  1 
ATOM   5288 C  CE  . LYS B  1 211 ? 23.47389 60.99291  -6.03717  1.000 34.40382 ? 242  LYS B CE  1 
ATOM   5289 N  NZ  . LYS B  1 211 ? 23.18769 61.96318  -7.14641  1.000 37.89319 ? 242  LYS B NZ  1 
ATOM   5290 N  N   . LYS B  1 212 ? 18.83002 61.89547  -0.54728  1.000 23.88660 ? 243  LYS B N   1 
ATOM   5291 C  CA  . LYS B  1 212 ? 17.44329 61.72516  -0.12534  1.000 23.83261 ? 243  LYS B CA  1 
ATOM   5292 C  C   . LYS B  1 212 ? 16.60018 61.17250  -1.27945  1.000 30.13085 ? 243  LYS B C   1 
ATOM   5293 O  O   . LYS B  1 212 ? 15.51274 61.66256  -1.59770  1.000 27.61956 ? 243  LYS B O   1 
ATOM   5294 C  CB  . LYS B  1 212 ? 16.87745 63.03495  0.42770   1.000 28.36843 ? 243  LYS B CB  1 
ATOM   5295 C  CG  . LYS B  1 212 ? 17.64968 63.51253  1.65620   1.000 29.14774 ? 243  LYS B CG  1 
ATOM   5296 C  CD  . LYS B  1 212 ? 17.11620 64.82064  2.20258   1.000 41.38189 ? 243  LYS B CD  1 
ATOM   5297 C  CE  . LYS B  1 212 ? 17.78797 65.14262  3.52559   1.000 43.41878 ? 243  LYS B CE  1 
ATOM   5298 N  NZ  . LYS B  1 212 ? 18.11855 66.59071  3.64132   1.000 44.97958 ? 243  LYS B NZ  1 
ATOM   5299 N  N   . GLN B  1 213 ? 17.12975 60.11432  -1.90017  1.000 23.68109 ? 244  GLN B N   1 
ATOM   5300 C  CA  . GLN B  1 213 ? 16.62768 59.39094  -3.04865  1.000 25.09372 ? 244  GLN B CA  1 
ATOM   5301 C  C   . GLN B  1 213 ? 16.52218 57.91794  -2.68236  1.000 22.63285 ? 244  GLN B C   1 
ATOM   5302 O  O   . GLN B  1 213 ? 17.45639 57.37929  -2.08968  1.000 21.73136 ? 244  GLN B O   1 
ATOM   5303 C  CB  . GLN B  1 213 ? 17.60471 59.53940  -4.22684  1.000 27.88582 ? 244  GLN B CB  1 
ATOM   5304 C  CG  . GLN B  1 213 ? 16.99642 59.87316  -5.55078  1.000 33.96480 ? 244  GLN B CG  1 
ATOM   5305 C  CD  . GLN B  1 213 ? 18.03714 59.94641  -6.65015  1.000 29.04521 ? 244  GLN B CD  1 
ATOM   5306 O  OE1 . GLN B  1 213 ? 19.16231 60.40978  -6.43514  1.000 31.79214 ? 244  GLN B OE1 1 
ATOM   5307 N  NE2 . GLN B  1 213 ? 17.67506 59.47146  -7.83241  1.000 31.00870 ? 244  GLN B NE2 1 
ATOM   5308 N  N   . PRO B  1 214 ? 15.41517 57.24846  -2.99719  1.000 20.63436 ? 245  PRO B N   1 
ATOM   5309 C  CA  . PRO B  1 214 ? 15.38343 55.78844  -2.83006  1.000 20.14929 ? 245  PRO B CA  1 
ATOM   5310 C  C   . PRO B  1 214 ? 16.48750 55.16295  -3.66578  1.000 20.35929 ? 245  PRO B C   1 
ATOM   5311 O  O   . PRO B  1 214 ? 16.78844 55.62836  -4.76813  1.000 22.37825 ? 245  PRO B O   1 
ATOM   5312 C  CB  . PRO B  1 214 ? 13.99404 55.38675  -3.34752  1.000 22.34487 ? 245  PRO B CB  1 
ATOM   5313 C  CG  . PRO B  1 214 ? 13.21213 56.68359  -3.42325  1.000 25.64169 ? 245  PRO B CG  1 
ATOM   5314 C  CD  . PRO B  1 214 ? 14.22056 57.75311  -3.69616  1.000 22.69277 ? 245  PRO B CD  1 
ATOM   5315 N  N   . PHE B  1 215 ? 17.10569 54.10650  -3.14148  1.000 18.55655 ? 246  PHE B N   1 
ATOM   5316 C  CA  . PHE B  1 215 ? 18.14540 53.44369  -3.90938  1.000 19.63532 ? 246  PHE B CA  1 
ATOM   5317 C  C   . PHE B  1 215 ? 17.68581 52.08772  -4.42453  1.000 17.30121 ? 246  PHE B C   1 
ATOM   5318 O  O   . PHE B  1 215 ? 16.82843 51.42207  -3.83318  1.000 19.79198 ? 246  PHE B O   1 
ATOM   5319 C  CB  . PHE B  1 215 ? 19.46479 53.28622  -3.11952  1.000 20.66851 ? 246  PHE B CB  1 
ATOM   5320 C  CG  . PHE B  1 215 ? 19.40767 52.35639  -1.92271  1.000 17.50526 ? 246  PHE B CG  1 
ATOM   5321 C  CD1 . PHE B  1 215 ? 19.37641 50.96713  -2.07608  1.000 18.91923 ? 246  PHE B CD1 1 
ATOM   5322 C  CD2 . PHE B  1 215 ? 19.46717 52.87645  -0.63988  1.000 20.14625 ? 246  PHE B CD2 1 
ATOM   5323 C  CE1 . PHE B  1 215 ? 19.35583 50.12614  -0.97535  1.000 19.97447 ? 246  PHE B CE1 1 
ATOM   5324 C  CE2 . PHE B  1 215 ? 19.46814 52.03835  0.47174   1.000 20.38866 ? 246  PHE B CE2 1 
ATOM   5325 C  CZ  . PHE B  1 215 ? 19.40542 50.66594  0.30864   1.000 22.05646 ? 246  PHE B CZ  1 
ATOM   5326 N  N   . PHE B  1 216 ? 18.26827 51.69970  -5.55175  1.000 18.82633 ? 247  PHE B N   1 
ATOM   5327 C  CA  . PHE B  1 216 ? 18.28574 50.31553  -6.01633  1.000 17.26895 ? 247  PHE B CA  1 
ATOM   5328 C  C   . PHE B  1 216 ? 19.74455 49.90940  -6.14009  1.000 19.18791 ? 247  PHE B C   1 
ATOM   5329 O  O   . PHE B  1 216 ? 20.48256 50.49827  -6.93572  1.000 20.32971 ? 247  PHE B O   1 
ATOM   5330 C  CB  . PHE B  1 216 ? 17.57868 50.17010  -7.36475  1.000 18.66407 ? 247  PHE B CB  1 
ATOM   5331 C  CG  . PHE B  1 216 ? 17.73747 48.81103  -7.99049  1.000 19.07169 ? 247  PHE B CG  1 
ATOM   5332 C  CD1 . PHE B  1 216 ? 17.12099 47.70742  -7.42836  1.000 18.82301 ? 247  PHE B CD1 1 
ATOM   5333 C  CD2 . PHE B  1 216 ? 18.50009 48.63405  -9.13966  1.000 19.33554 ? 247  PHE B CD2 1 
ATOM   5334 C  CE1 . PHE B  1 216 ? 17.24510 46.45543  -8.00054  1.000 20.07212 ? 247  PHE B CE1 1 
ATOM   5335 C  CE2 . PHE B  1 216 ? 18.64092 47.38010  -9.71689  1.000 20.46547 ? 247  PHE B CE2 1 
ATOM   5336 C  CZ  . PHE B  1 216 ? 18.00750 46.28022  -9.13846  1.000 19.77206 ? 247  PHE B CZ  1 
ATOM   5337 N  N   . ILE B  1 217 ? 20.17330 48.93554  -5.34205  1.000 18.39552 ? 248  ILE B N   1 
ATOM   5338 C  CA  . ILE B  1 217 ? 21.56207 48.48080  -5.37184  1.000 19.46849 ? 248  ILE B CA  1 
ATOM   5339 C  C   . ILE B  1 217 ? 21.55144 47.00989  -5.73750  1.000 16.93280 ? 248  ILE B C   1 
ATOM   5340 O  O   . ILE B  1 217 ? 20.90736 46.20371  -5.06054  1.000 16.83030 ? 248  ILE B O   1 
ATOM   5341 C  CB  . ILE B  1 217 ? 22.28622 48.70501  -4.03832  1.000 18.37540 ? 248  ILE B CB  1 
ATOM   5342 C  CG1 . ILE B  1 217 ? 22.40185 50.20643  -3.74672  1.000 19.46854 ? 248  ILE B CG1 1 
ATOM   5343 C  CG2 . ILE B  1 217 ? 23.68113 48.06192  -4.08598  1.000 18.38482 ? 248  ILE B CG2 1 
ATOM   5344 C  CD1 . ILE B  1 217 ? 22.91772 50.51845  -2.37189  1.000 18.41531 ? 248  ILE B CD1 1 
ATOM   5345 N  N   . TYR B  1 218 ? 22.24133 46.67905  -6.82302  1.000 16.44704 ? 249  TYR B N   1 
ATOM   5346 C  CA  . TYR B  1 218 ? 22.38513 45.31625  -7.32564  1.000 17.09894 ? 249  TYR B CA  1 
ATOM   5347 C  C   . TYR B  1 218 ? 23.77915 44.87492  -6.90166  1.000 20.14834 ? 249  TYR B C   1 
ATOM   5348 O  O   . TYR B  1 218 ? 24.77060 45.21274  -7.55398  1.000 19.15101 ? 249  TYR B O   1 
ATOM   5349 C  CB  . TYR B  1 218 ? 22.19166 45.32070  -8.83855  1.000 17.25160 ? 249  TYR B CB  1 
ATOM   5350 C  CG  . TYR B  1 218 ? 22.39397 44.00812  -9.56924  1.000 17.16101 ? 249  TYR B CG  1 
ATOM   5351 C  CD1 . TYR B  1 218 ? 21.43431 43.00727  -9.51575  1.000 19.98802 ? 249  TYR B CD1 1 
ATOM   5352 C  CD2 . TYR B  1 218 ? 23.52203 43.79066  -10.36084 1.000 18.35999 ? 249  TYR B CD2 1 
ATOM   5353 C  CE1 . TYR B  1 218 ? 21.59565 41.81385  -10.20300 1.000 19.40966 ? 249  TYR B CE1 1 
ATOM   5354 C  CE2 . TYR B  1 218 ? 23.69464 42.59506  -11.05407 1.000 17.96347 ? 249  TYR B CE2 1 
ATOM   5355 C  CZ  . TYR B  1 218 ? 22.71999 41.60911  -10.96702 1.000 18.72639 ? 249  TYR B CZ  1 
ATOM   5356 O  OH  . TYR B  1 218 ? 22.85867 40.42271  -11.65375 1.000 19.05616 ? 249  TYR B OH  1 
ATOM   5357 N  N   . LEU B  1 219 ? 23.86512 44.17155  -5.76994  1.000 15.82226 ? 250  LEU B N   1 
ATOM   5358 C  CA  . LEU B  1 219 ? 25.15371 43.78953  -5.18938  1.000 16.63793 ? 250  LEU B CA  1 
ATOM   5359 C  C   . LEU B  1 219 ? 25.43885 42.34430  -5.59083  1.000 17.65980 ? 250  LEU B C   1 
ATOM   5360 O  O   . LEU B  1 219 ? 24.92601 41.39972  -4.98557  1.000 17.13104 ? 250  LEU B O   1 
ATOM   5361 C  CB  . LEU B  1 219 ? 25.12625 43.99685  -3.67697  1.000 15.99398 ? 250  LEU B CB  1 
ATOM   5362 C  CG  . LEU B  1 219 ? 26.29182 43.45674  -2.85486  1.000 17.13394 ? 250  LEU B CG  1 
ATOM   5363 C  CD1 . LEU B  1 219 ? 27.63407 44.02548  -3.34773  1.000 20.35391 ? 250  LEU B CD1 1 
ATOM   5364 C  CD2 . LEU B  1 219 ? 26.07358 43.81347  -1.38360  1.000 16.62382 ? 250  LEU B CD2 1 
ATOM   5365 N  N   . ALA B  1 220 ? 26.24724 42.17512  -6.63455  1.000 18.44278 ? 251  ALA B N   1 
ATOM   5366 C  CA  . ALA B  1 220 ? 26.44879 40.87792  -7.26881  1.000 17.91746 ? 251  ALA B CA  1 
ATOM   5367 C  C   . ALA B  1 220 ? 27.81630 40.34406  -6.85543  1.000 18.58972 ? 251  ALA B C   1 
ATOM   5368 O  O   . ALA B  1 220 ? 28.78577 40.41041  -7.60556  1.000 19.27442 ? 251  ALA B O   1 
ATOM   5369 C  CB  . ALA B  1 220 ? 26.32081 40.99187  -8.79133  1.000 17.88182 ? 251  ALA B CB  1 
ATOM   5370 N  N   . TYR B  1 221 ? 27.88946 39.82674  -5.63730  1.000 16.93211 ? 252  TYR B N   1 
ATOM   5371 C  CA  . TYR B  1 221 ? 29.12109 39.19428  -5.18125  1.000 16.40654 ? 252  TYR B CA  1 
ATOM   5372 C  C   . TYR B  1 221 ? 29.51307 38.06180  -6.12103  1.000 17.65484 ? 252  TYR B C   1 
ATOM   5373 O  O   . TYR B  1 221 ? 28.66590 37.26869  -6.54753  1.000 17.28135 ? 252  TYR B O   1 
ATOM   5374 C  CB  . TYR B  1 221 ? 28.94071 38.61688  -3.78221  1.000 17.23516 ? 252  TYR B CB  1 
ATOM   5375 C  CG  . TYR B  1 221 ? 28.83651 39.61498  -2.65239  1.000 17.68284 ? 252  TYR B CG  1 
ATOM   5376 C  CD1 . TYR B  1 221 ? 29.94353 40.33498  -2.22606  1.000 16.82341 ? 252  TYR B CD1 1 
ATOM   5377 C  CD2 . TYR B  1 221 ? 27.63613 39.79015  -1.97310  1.000 17.01725 ? 252  TYR B CD2 1 
ATOM   5378 C  CE1 . TYR B  1 221 ? 29.84882 41.21884  -1.16827  1.000 18.74698 ? 252  TYR B CE1 1 
ATOM   5379 C  CE2 . TYR B  1 221 ? 27.52979 40.66683  -0.91386  1.000 17.38719 ? 252  TYR B CE2 1 
ATOM   5380 C  CZ  . TYR B  1 221 ? 28.63440 41.38089  -0.51915  1.000 16.68325 ? 252  TYR B CZ  1 
ATOM   5381 O  OH  . TYR B  1 221 ? 28.53487 42.24147  0.54137   1.000 18.94216 ? 252  TYR B OH  1 
ATOM   5382 N  N   . ASN B  1 222 ? 30.81157 37.95336  -6.42877  1.000 18.06016 ? 253  ASN B N   1 
ATOM   5383 C  CA  . ASN B  1 222 ? 31.18998 36.72996  -7.12481  1.000 17.78341 ? 253  ASN B CA  1 
ATOM   5384 C  C   . ASN B  1 222 ? 31.36810 35.55035  -6.17658  1.000 15.13307 ? 253  ASN B C   1 
ATOM   5385 O  O   . ASN B  1 222 ? 31.36489 34.41132  -6.63886  1.000 17.26214 ? 253  ASN B O   1 
ATOM   5386 C  CB  . ASN B  1 222 ? 32.44693 36.92902  -7.99309  1.000 17.27032 ? 253  ASN B CB  1 
ATOM   5387 C  CG  . ASN B  1 222 ? 33.67660 37.32864  -7.20699  1.000 18.63742 ? 253  ASN B CG  1 
ATOM   5388 O  OD1 . ASN B  1 222 ? 33.63560 38.21505  -6.35223  1.000 19.80319 ? 253  ASN B OD1 1 
ATOM   5389 N  ND2 . ASN B  1 222 ? 34.81234 36.69925  -7.54368  1.000 17.45807 ? 253  ASN B ND2 1 
ATOM   5390 N  N   . ALA B  1 223 ? 31.44250 35.78040  -4.86738  1.000 16.39862 ? 254  ALA B N   1 
ATOM   5391 C  CA  . ALA B  1 223 ? 31.53102 34.66771  -3.93277  1.000 15.90118 ? 254  ALA B CA  1 
ATOM   5392 C  C   . ALA B  1 223 ? 30.21239 33.89477  -3.89576  1.000 17.78704 ? 254  ALA B C   1 
ATOM   5393 O  O   . ALA B  1 223 ? 29.13852 34.48241  -4.04006  1.000 18.15177 ? 254  ALA B O   1 
ATOM   5394 C  CB  . ALA B  1 223 ? 31.85749 35.16978  -2.53084  1.000 17.43901 ? 254  ALA B CB  1 
ATOM   5395 N  N   . PRO B  1 224 ? 30.26136 32.57281  -3.68144  1.000 16.57113 ? 255  PRO B N   1 
ATOM   5396 C  CA  . PRO B  1 224 ? 31.44310 31.70626  -3.53400  1.000 16.74651 ? 255  PRO B CA  1 
ATOM   5397 C  C   . PRO B  1 224 ? 31.87026 30.99580  -4.83105  1.000 18.17283 ? 255  PRO B C   1 
ATOM   5398 O  O   . PRO B  1 224 ? 32.29654 29.85446  -4.78034  1.000 18.14505 ? 255  PRO B O   1 
ATOM   5399 C  CB  . PRO B  1 224 ? 30.97173 30.70992  -2.47790  1.000 18.39989 ? 255  PRO B CB  1 
ATOM   5400 C  CG  . PRO B  1 224 ? 29.52412 30.46010  -2.88666  1.000 15.87609 ? 255  PRO B CG  1 
ATOM   5401 C  CD  . PRO B  1 224 ? 29.02085 31.84426  -3.32376  1.000 15.54867 ? 255  PRO B CD  1 
ATOM   5402 N  N   . HIS B  1 225 ? 31.78182 31.66298  -5.98156  1.000 17.88801 ? 256  HIS B N   1 
ATOM   5403 C  CA  . HIS B  1 225 ? 32.22878 31.11442  -7.26133  1.000 18.69446 ? 256  HIS B CA  1 
ATOM   5404 C  C   . HIS B  1 225 ? 33.75277 30.96338  -7.27300  1.000 20.35225 ? 256  HIS B C   1 
ATOM   5405 O  O   . HIS B  1 225 ? 34.48255 31.75112  -6.66662  1.000 17.39073 ? 256  HIS B O   1 
ATOM   5406 C  CB  . HIS B  1 225 ? 31.76659 32.05857  -8.38464  1.000 17.00169 ? 256  HIS B CB  1 
ATOM   5407 C  CG  . HIS B  1 225 ? 31.94080 31.54611  -9.78521  1.000 18.53169 ? 256  HIS B CG  1 
ATOM   5408 N  ND1 . HIS B  1 225 ? 33.17617 31.36755  -10.37123 1.000 19.29956 ? 256  HIS B ND1 1 
ATOM   5409 C  CD2 . HIS B  1 225 ? 31.02690 31.27116  -10.74607 1.000 19.53155 ? 256  HIS B CD2 1 
ATOM   5410 C  CE1 . HIS B  1 225 ? 33.01448 30.94533  -11.61447 1.000 20.44266 ? 256  HIS B CE1 1 
ATOM   5411 N  NE2 . HIS B  1 225 ? 31.71887 30.88477  -11.87046 1.000 21.53843 ? 256  HIS B NE2 1 
ATOM   5412 N  N   . VAL B  1 226 ? 34.22685 29.93705  -7.97074  1.000 17.41017 ? 257  VAL B N   1 
ATOM   5413 C  CA  . VAL B  1 226 ? 35.66129 29.69656  -8.12197  1.000 18.91661 ? 257  VAL B CA  1 
ATOM   5414 C  C   . VAL B  1 226 ? 36.33903 30.93307  -8.70714  1.000 19.04745 ? 257  VAL B C   1 
ATOM   5415 O  O   . VAL B  1 226 ? 35.70431 31.70946  -9.43743  1.000 19.17123 ? 257  VAL B O   1 
ATOM   5416 C  CB  . VAL B  1 226 ? 35.92322 28.45189  -8.98973  1.000 17.68733 ? 257  VAL B CB  1 
ATOM   5417 C  CG1 . VAL B  1 226 ? 35.49203 27.17966  -8.24718  1.000 18.23415 ? 257  VAL B CG1 1 
ATOM   5418 C  CG2 . VAL B  1 226 ? 35.20233 28.55578  -10.33302 1.000 20.20462 ? 257  VAL B CG2 1 
ATOM   5419 N  N   . PRO B  1 227 ? 37.63282 31.14766  -8.43444  1.000 18.47818 ? 258  PRO B N   1 
ATOM   5420 C  CA  . PRO B  1 227 ? 38.54364 30.27900  -7.67285  1.000 19.68259 ? 258  PRO B CA  1 
ATOM   5421 C  C   . PRO B  1 227 ? 38.26866 30.29851  -6.17590  1.000 18.08262 ? 258  PRO B C   1 
ATOM   5422 O  O   . PRO B  1 227 ? 37.85151 31.31843  -5.62986  1.000 20.08017 ? 258  PRO B O   1 
ATOM   5423 C  CB  . PRO B  1 227 ? 39.92685 30.86843  -8.00122  1.000 19.53825 ? 258  PRO B CB  1 
ATOM   5424 C  CG  . PRO B  1 227 ? 39.64891 32.33456  -8.23267  1.000 19.85132 ? 258  PRO B CG  1 
ATOM   5425 C  CD  . PRO B  1 227 ? 38.31164 32.35365  -8.94059  1.000 17.55111 ? 258  PRO B CD  1 
ATOM   5426 N  N   . LEU B  1 228 ? 38.47409 29.17776  -5.48769  1.000 17.81706 ? 259  LEU B N   1 
ATOM   5427 C  CA  . LEU B  1 228 ? 38.27827 29.13710  -4.03990  1.000 19.23011 ? 259  LEU B CA  1 
ATOM   5428 C  C   . LEU B  1 228 ? 39.46154 29.84342  -3.38478  1.000 19.44986 ? 259  LEU B C   1 
ATOM   5429 O  O   . LEU B  1 228 ? 40.57154 29.30213  -3.30165  1.000 21.06232 ? 259  LEU B O   1 
ATOM   5430 C  CB  . LEU B  1 228 ? 38.11482 27.70047  -3.55755  1.000 19.67833 ? 259  LEU B CB  1 
ATOM   5431 C  CG  . LEU B  1 228 ? 36.97929 26.88028  -4.19353  1.000 21.43015 ? 259  LEU B CG  1 
ATOM   5432 C  CD1 . LEU B  1 228 ? 36.87610 25.50760  -3.51957  1.000 23.53771 ? 259  LEU B CD1 1 
ATOM   5433 C  CD2 . LEU B  1 228 ? 35.65859 27.63672  -4.10021  1.000 19.73941 ? 259  LEU B CD2 1 
ATOM   5434 N  N   . GLN B  1 229 ? 39.22808 31.07345  -2.93184  1.000 18.13074 ? 260  GLN B N   1 
ATOM   5435 C  CA  . GLN B  1 229 ? 40.25229 31.94143  -2.36458  1.000 20.23292 ? 260  GLN B CA  1 
ATOM   5436 C  C   . GLN B  1 229 ? 39.61903 32.69863  -1.20997  1.000 18.73687 ? 260  GLN B C   1 
ATOM   5437 O  O   . GLN B  1 229 ? 38.58702 33.34629  -1.40041  1.000 20.60191 ? 260  GLN B O   1 
ATOM   5438 C  CB  . GLN B  1 229 ? 40.79619 32.92276  -3.41505  1.000 21.85605 ? 260  GLN B CB  1 
ATOM   5439 C  CG  . GLN B  1 229 ? 41.40917 32.21863  -4.63135  1.000 21.39094 ? 260  GLN B CG  1 
ATOM   5440 C  CD  . GLN B  1 229 ? 41.93909 33.16057  -5.70276  1.000 22.85018 ? 260  GLN B CD  1 
ATOM   5441 O  OE1 . GLN B  1 229 ? 41.57885 34.33957  -5.77201  1.000 21.20925 ? 260  GLN B OE1 1 
ATOM   5442 N  NE2 . GLN B  1 229 ? 42.79895 32.62717  -6.56507  1.000 23.49545 ? 260  GLN B NE2 1 
ATOM   5443 N  N   . ALA B  1 230 ? 40.22845 32.61439  -0.02560  1.000 19.35749 ? 261  ALA B N   1 
ATOM   5444 C  CA  . ALA B  1 230 ? 39.64258 33.18367  1.17975   1.000 20.24225 ? 261  ALA B CA  1 
ATOM   5445 C  C   . ALA B  1 230 ? 40.72211 33.81539  2.04682   1.000 20.88436 ? 261  ALA B C   1 
ATOM   5446 O  O   . ALA B  1 230 ? 41.90323 33.46273  1.96334   1.000 22.69891 ? 261  ALA B O   1 
ATOM   5447 C  CB  . ALA B  1 230 ? 38.87999 32.12071  1.98333   1.000 21.53405 ? 261  ALA B CB  1 
ATOM   5448 N  N   . LYS B  1 231 ? 40.28648 34.75292  2.89247   1.000 19.41148 ? 262  LYS B N   1 
ATOM   5449 C  CA  . LYS B  1 231 ? 41.17190 35.39878  3.85926   1.000 19.61559 ? 262  LYS B CA  1 
ATOM   5450 C  C   . LYS B  1 231 ? 41.48817 34.46365  5.01330   1.000 21.35819 ? 262  LYS B C   1 
ATOM   5451 O  O   . LYS B  1 231 ? 40.63644 33.69036  5.45614   1.000 21.27670 ? 262  LYS B O   1 
ATOM   5452 C  CB  . LYS B  1 231 ? 40.52519 36.66634  4.41834   1.000 19.41727 ? 262  LYS B CB  1 
ATOM   5453 C  CG  . LYS B  1 231 ? 40.23121 37.72185  3.36566   1.000 22.05168 ? 262  LYS B CG  1 
ATOM   5454 C  CD  . LYS B  1 231 ? 39.36043 38.84772  3.92935   1.000 23.85150 ? 262  LYS B CD  1 
ATOM   5455 C  CE  . LYS B  1 231 ? 40.05085 39.62856  5.03922   1.000 28.06420 ? 262  LYS B CE  1 
ATOM   5456 N  NZ  . LYS B  1 231 ? 39.09985 40.62536  5.66891   1.000 24.13661 ? 262  LYS B NZ  1 
ATOM   5457 N  N   . ALA B  1 232 ? 42.71969 34.56539  5.52252   1.000 22.46605 ? 263  ALA B N   1 
ATOM   5458 C  CA  . ALA B  1 232 ? 43.13392 33.72105  6.63847   1.000 23.04982 ? 263  ALA B CA  1 
ATOM   5459 C  C   . ALA B  1 232 ? 42.25359 33.93392  7.85932   1.000 21.80816 ? 263  ALA B C   1 
ATOM   5460 O  O   . ALA B  1 232 ? 41.93739 32.97660  8.57303   1.000 24.99034 ? 263  ALA B O   1 
ATOM   5461 C  CB  . ALA B  1 232 ? 44.60036 33.99187  6.98346   1.000 27.60207 ? 263  ALA B CB  1 
ATOM   5462 N  N   . GLU B  1 233 ? 41.84454 35.18088  8.11701   1.000 20.90807 ? 264  GLU B N   1 
ATOM   5463 C  CA  . GLU B  1 233 ? 41.00088 35.45749  9.27579   1.000 24.45272 ? 264  GLU B CA  1 
ATOM   5464 C  C   . GLU B  1 233 ? 39.64471 34.77008  9.16176   1.000 23.74107 ? 264  GLU B C   1 
ATOM   5465 O  O   . GLU B  1 233 ? 39.05300 34.37967  10.17822  1.000 23.32679 ? 264  GLU B O   1 
ATOM   5466 C  CB  . GLU B  1 233 ? 40.81215 36.96785  9.44598   1.000 28.26743 ? 264  GLU B CB  1 
ATOM   5467 C  CG  . GLU B  1 233 ? 42.11307 37.76145  9.53133   1.000 31.19244 ? 264  GLU B CG  1 
ATOM   5468 C  CD  . GLU B  1 233 ? 42.50676 38.41976  8.20796   1.000 37.23566 ? 264  GLU B CD  1 
ATOM   5469 O  OE1 . GLU B  1 233 ? 42.59242 37.72501  7.16143   1.000 27.24590 ? 264  GLU B OE1 1 
ATOM   5470 O  OE2 . GLU B  1 233 ? 42.73893 39.64912  8.22007   1.000 43.25435 ? 264  GLU B OE2 1 
ATOM   5471 N  N   . ASP B  1 234 ? 39.13635 34.61483  7.94102   1.000 22.28986 ? 265  ASP B N   1 
ATOM   5472 C  CA  . ASP B  1 234 ? 37.86587 33.92887  7.73662   1.000 21.43362 ? 265  ASP B CA  1 
ATOM   5473 C  C   . ASP B  1 234 ? 38.03268 32.40915  7.77444   1.000 20.88797 ? 265  ASP B C   1 
ATOM   5474 O  O   . ASP B  1 234 ? 37.17938 31.70399  8.32320   1.000 21.99720 ? 265  ASP B O   1 
ATOM   5475 C  CB  . ASP B  1 234 ? 37.24770 34.36169  6.40443   1.000 19.78309 ? 265  ASP B CB  1 
ATOM   5476 C  CG  . ASP B  1 234 ? 36.84911 35.83007  6.38706   1.000 22.30406 ? 265  ASP B CG  1 
ATOM   5477 O  OD1 . ASP B  1 234 ? 36.57479 36.38992  7.47322   1.000 24.15310 ? 265  ASP B OD1 1 
ATOM   5478 O  OD2 . ASP B  1 234 ? 36.80880 36.42119  5.28170   1.000 19.95302 ? 265  ASP B OD2 1 
ATOM   5479 N  N   . VAL B  1 235 ? 39.12458 31.89048  7.19894   1.000 20.55680 ? 266  VAL B N   1 
ATOM   5480 C  CA  . VAL B  1 235 ? 39.37888 30.45160  7.21880   1.000 23.03249 ? 266  VAL B CA  1 
ATOM   5481 C  C   . VAL B  1 235 ? 39.52940 29.95616  8.65036   1.000 21.41138 ? 266  VAL B C   1 
ATOM   5482 O  O   . VAL B  1 235 ? 39.11540 28.83746  8.97654   1.000 23.59982 ? 266  VAL B O   1 
ATOM   5483 C  CB  . VAL B  1 235 ? 40.62018 30.12743  6.35428   1.000 23.24971 ? 266  VAL B CB  1 
ATOM   5484 C  CG1 . VAL B  1 235 ? 41.04960 28.66408  6.50810   1.000 25.84577 ? 266  VAL B CG1 1 
ATOM   5485 C  CG2 . VAL B  1 235 ? 40.34856 30.44168  4.89538   1.000 22.95586 ? 266  VAL B CG2 1 
ATOM   5486 N  N   . ALA B  1 236 ? 40.07750 30.79428  9.53748   1.000 22.35538 ? 267  ALA B N   1 
ATOM   5487 C  CA  . ALA B  1 236 ? 40.28354 30.39974  10.92774  1.000 22.94629 ? 267  ALA B CA  1 
ATOM   5488 C  C   . ALA B  1 236 ? 38.98013 30.10612  11.65683  1.000 30.55031 ? 267  ALA B C   1 
ATOM   5489 O  O   . ALA B  1 236 ? 39.00264 29.43122  12.69056  1.000 31.65360 ? 267  ALA B O   1 
ATOM   5490 C  CB  . ALA B  1 236 ? 41.05439 31.49237  11.67120  1.000 29.98585 ? 267  ALA B CB  1 
ATOM   5491 N  N   . LYS B  1 237 ? 37.84814 30.59679  11.15266  1.000 24.30499 ? 268  LYS B N   1 
ATOM   5492 C  CA  . LYS B  1 237 ? 36.55172 30.31407  11.75877  1.000 24.44741 ? 268  LYS B CA  1 
ATOM   5493 C  C   . LYS B  1 237 ? 36.02402 28.92467  11.42498  1.000 26.51755 ? 268  LYS B C   1 
ATOM   5494 O  O   . LYS B  1 237 ? 34.96751 28.53968  11.94035  1.000 25.92126 ? 268  LYS B O   1 
ATOM   5495 C  CB  . LYS B  1 237 ? 35.52278 31.35330  11.30156  1.000 24.31431 ? 268  LYS B CB  1 
ATOM   5496 C  CG  . LYS B  1 237 ? 35.92821 32.79869  11.54805  1.000 30.90778 ? 268  LYS B CG  1 
ATOM   5497 C  CD  . LYS B  1 237 ? 35.70484 33.18336  12.98942  1.000 37.60509 ? 268  LYS B CD  1 
ATOM   5498 C  CE  . LYS B  1 237 ? 35.43124 34.67888  13.12725  1.000 38.38279 ? 268  LYS B CE  1 
ATOM   5499 N  NZ  . LYS B  1 237 ? 36.68198 35.48196  13.13142  1.000 40.97422 ? 268  LYS B NZ  1 
ATOM   5500 N  N   . PHE B  1 238 ? 36.71188 28.16620  10.57320  1.000 22.95246 ? 269  PHE B N   1 
ATOM   5501 C  CA  . PHE B  1 238 ? 36.12194 26.95422  10.02181  1.000 23.12966 ? 269  PHE B CA  1 
ATOM   5502 C  C   . PHE B  1 238 ? 37.04270 25.75258  10.16558  1.000 25.05987 ? 269  PHE B C   1 
ATOM   5503 O  O   . PHE B  1 238 ? 37.04279 24.85599  9.32404   1.000 24.35752 ? 269  PHE B O   1 
ATOM   5504 C  CB  . PHE B  1 238 ? 35.70714 27.19407  8.57427   1.000 22.02852 ? 269  PHE B CB  1 
ATOM   5505 C  CG  . PHE B  1 238 ? 34.59737 28.18657  8.47186   1.000 20.66571 ? 269  PHE B CG  1 
ATOM   5506 C  CD1 . PHE B  1 238 ? 33.29541 27.79412  8.73645   1.000 22.87870 ? 269  PHE B CD1 1 
ATOM   5507 C  CD2 . PHE B  1 238 ? 34.86085 29.52296  8.21470   1.000 22.48915 ? 269  PHE B CD2 1 
ATOM   5508 C  CE1 . PHE B  1 238 ? 32.25879 28.70457  8.70093   1.000 21.73944 ? 269  PHE B CE1 1 
ATOM   5509 C  CE2 . PHE B  1 238 ? 33.82458 30.45120  8.18033   1.000 21.27472 ? 269  PHE B CE2 1 
ATOM   5510 C  CZ  . PHE B  1 238 ? 32.52093 30.03279  8.41848   1.000 24.20088 ? 269  PHE B CZ  1 
ATOM   5511 N  N   . ALA B  1 239 ? 37.80221 25.70877  11.26074  1.000 26.28523 ? 270  ALA B N   1 
ATOM   5512 C  CA  . ALA B  1 239 ? 38.59369 24.52364  11.56638  1.000 26.54565 ? 270  ALA B CA  1 
ATOM   5513 C  C   . ALA B  1 239 ? 37.73407 23.27223  11.69804  1.000 28.13816 ? 270  ALA B C   1 
ATOM   5514 O  O   . ALA B  1 239 ? 38.24403 22.16082  11.51290  1.000 29.56121 ? 270  ALA B O   1 
ATOM   5515 C  CB  . ALA B  1 239 ? 39.38868 24.75260  12.85536  1.000 33.62081 ? 270  ALA B CB  1 
ATOM   5516 N  N   . HIS B  1 240 ? 36.44132 23.41923  12.00838  1.000 25.62453 ? 271  HIS B N   1 
ATOM   5517 C  CA  . HIS B  1 240 ? 35.57727 22.25326  12.14764  1.000 25.85924 ? 271  HIS B CA  1 
ATOM   5518 C  C   . HIS B  1 240 ? 35.23186 21.60516  10.81440  1.000 28.64234 ? 271  HIS B C   1 
ATOM   5519 O  O   . HIS B  1 240 ? 34.65282 20.51186  10.80762  1.000 26.61395 ? 271  HIS B O   1 
ATOM   5520 C  CB  . HIS B  1 240 ? 34.29268 22.63796  12.87857  1.000 27.79295 ? 271  HIS B CB  1 
ATOM   5521 C  CG  . HIS B  1 240 ? 33.51292 23.72070  12.19861  1.000 23.70128 ? 271  HIS B CG  1 
ATOM   5522 N  ND1 . HIS B  1 240 ? 33.83176 25.05522  12.32099  1.000 26.81071 ? 271  HIS B ND1 1 
ATOM   5523 C  CD2 . HIS B  1 240 ? 32.42083 23.66466  11.39764  1.000 26.32073 ? 271  HIS B CD2 1 
ATOM   5524 C  CE1 . HIS B  1 240 ? 32.97006 25.77688  11.62299  1.000 26.62577 ? 271  HIS B CE1 1 
ATOM   5525 N  NE2 . HIS B  1 240 ? 32.10427 24.95592  11.05348  1.000 24.80316 ? 271  HIS B NE2 1 
ATOM   5526 N  N   . ILE B  1 241 ? 35.56057 22.24591  9.69774   1.000 24.13723 ? 272  ILE B N   1 
ATOM   5527 C  CA  . ILE B  1 241 ? 35.30538 21.70386  8.37063   1.000 24.58529 ? 272  ILE B CA  1 
ATOM   5528 C  C   . ILE B  1 241 ? 36.58728 21.02387  7.90621   1.000 26.94953 ? 272  ILE B C   1 
ATOM   5529 O  O   . ILE B  1 241 ? 37.61566 21.67837  7.70438   1.000 25.72762 ? 272  ILE B O   1 
ATOM   5530 C  CB  . ILE B  1 241 ? 34.84457 22.79638  7.39670   1.000 24.23346 ? 272  ILE B CB  1 
ATOM   5531 C  CG1 . ILE B  1 241 ? 33.50211 23.36768  7.87940   1.000 24.49387 ? 272  ILE B CG1 1 
ATOM   5532 C  CG2 . ILE B  1 241 ? 34.72508 22.23658  5.99289   1.000 23.12546 ? 272  ILE B CG2 1 
ATOM   5533 C  CD1 . ILE B  1 241 ? 32.86737 24.41839  6.95038   1.000 23.12743 ? 272  ILE B CD1 1 
ATOM   5534 N  N   . LYS B  1 242 ? 36.53406 19.70310  7.75000   1.000 25.55725 ? 273  LYS B N   1 
ATOM   5535 C  CA  . LYS B  1 242 ? 37.75073 18.95679  7.45146   1.000 28.01864 ? 273  LYS B CA  1 
ATOM   5536 C  C   . LYS B  1 242 ? 38.08917 18.96494  5.96791   1.000 30.51037 ? 273  LYS B C   1 
ATOM   5537 O  O   . LYS B  1 242 ? 39.27308 18.94189  5.61317   1.000 40.20456 ? 273  LYS B O   1 
ATOM   5538 C  CB  . LYS B  1 242 ? 37.61612 17.52029  7.95451   1.000 30.76088 ? 273  LYS B CB  1 
ATOM   5539 C  CG  . LYS B  1 242 ? 37.21879 17.42023  9.41578   1.000 37.89680 ? 273  LYS B CG  1 
ATOM   5540 C  CD  . LYS B  1 242 ? 38.38512 17.71385  10.34968  1.000 40.69946 ? 273  LYS B CD  1 
ATOM   5541 C  CE  . LYS B  1 242 ? 38.29896 19.10333  10.94911  1.000 40.25741 ? 273  LYS B CE  1 
ATOM   5542 N  NZ  . LYS B  1 242 ? 39.07338 19.20643  12.22041  1.000 42.26967 ? 273  LYS B NZ  1 
ATOM   5543 N  N   . ASP B  1 243 ? 37.08869 19.00502  5.09327   1.000 26.45231 ? 274  ASP B N   1 
ATOM   5544 C  CA  . ASP B  1 243 ? 37.35605 19.00652  3.66297   1.000 24.49745 ? 274  ASP B CA  1 
ATOM   5545 C  C   . ASP B  1 243 ? 37.95856 20.34513  3.25886   1.000 27.56471 ? 274  ASP B C   1 
ATOM   5546 O  O   . ASP B  1 243 ? 37.39810 21.39666  3.56602   1.000 24.16000 ? 274  ASP B O   1 
ATOM   5547 C  CB  . ASP B  1 243 ? 36.07476 18.75111  2.87879   1.000 27.15408 ? 274  ASP B CB  1 
ATOM   5548 C  CG  . ASP B  1 243 ? 36.30221 18.78301  1.38246   1.000 34.75648 ? 274  ASP B CG  1 
ATOM   5549 O  OD1 . ASP B  1 243 ? 36.80956 17.77895  0.83124   1.000 36.85116 ? 274  ASP B OD1 1 
ATOM   5550 O  OD2 . ASP B  1 243 ? 35.99400 19.81521  0.75375   1.000 31.61526 ? 274  ASP B OD2 1 
ATOM   5551 N  N   . LYS B  1 244 ? 39.09178 20.30703  2.55150   1.000 28.19475 ? 275  LYS B N   1 
ATOM   5552 C  CA  . LYS B  1 244 ? 39.84992 21.53173  2.31723   1.000 26.84026 ? 275  LYS B CA  1 
ATOM   5553 C  C   . LYS B  1 244 ? 39.07831 22.51569  1.44444   1.000 24.34624 ? 275  LYS B C   1 
ATOM   5554 O  O   . LYS B  1 244 ? 39.08358 23.72468  1.70733   1.000 24.05119 ? 275  LYS B O   1 
ATOM   5555 C  CB  . LYS B  1 244 ? 41.19930 21.19941  1.67853   1.000 36.22704 ? 275  LYS B CB  1 
ATOM   5556 N  N   . ASP B  1 245 ? 38.41533 22.01903  0.40176   1.000 24.99272 ? 276  ASP B N   1 
ATOM   5557 C  CA  . ASP B  1 245 ? 37.67400 22.91776  -0.47387  1.000 25.21956 ? 276  ASP B CA  1 
ATOM   5558 C  C   . ASP B  1 245 ? 36.45730 23.49127  0.23280   1.000 21.01218 ? 276  ASP B C   1 
ATOM   5559 O  O   . ASP B  1 245 ? 36.16582 24.68533  0.09949   1.000 21.31936 ? 276  ASP B O   1 
ATOM   5560 C  CB  . ASP B  1 245 ? 37.26893 22.19476  -1.75373  1.000 27.11819 ? 276  ASP B CB  1 
ATOM   5561 C  CG  . ASP B  1 245 ? 38.40438 22.13289  -2.76213  1.000 28.34277 ? 276  ASP B CG  1 
ATOM   5562 O  OD1 . ASP B  1 245 ? 39.50949 22.63689  -2.45198  1.000 34.85472 ? 276  ASP B OD1 1 
ATOM   5563 O  OD2 . ASP B  1 245 ? 38.18274 21.60476  -3.85984  1.000 38.84324 ? 276  ASP B OD2 1 
ATOM   5564 N  N   . ARG B  1 246 ? 35.75465 22.67435  1.02011   1.000 20.45711 ? 277  ARG B N   1 
ATOM   5565 C  CA  . ARG B  1 246 ? 34.59475 23.22359  1.71403   1.000 19.08158 ? 277  ARG B CA  1 
ATOM   5566 C  C   . ARG B  1 246 ? 35.00021 24.24479  2.76797   1.000 20.98254 ? 277  ARG B C   1 
ATOM   5567 O  O   . ARG B  1 246 ? 34.27008 25.21705  3.00256   1.000 19.49516 ? 277  ARG B O   1 
ATOM   5568 C  CB  . ARG B  1 246 ? 33.76759 22.11954  2.35304   1.000 21.30467 ? 277  ARG B CB  1 
ATOM   5569 C  CG  . ARG B  1 246 ? 32.53737 22.67245  3.05979   1.000 23.63191 ? 277  ARG B CG  1 
ATOM   5570 C  CD  . ARG B  1 246 ? 31.33346 21.84943  2.78317   1.000 25.97766 ? 277  ARG B CD  1 
ATOM   5571 N  NE  . ARG B  1 246 ? 30.15746 22.35357  3.48127   1.000 21.97984 ? 277  ARG B NE  1 
ATOM   5572 C  CZ  . ARG B  1 246 ? 29.13053 22.94248  2.88508   1.000 21.35523 ? 277  ARG B CZ  1 
ATOM   5573 N  NH1 . ARG B  1 246 ? 29.16484 23.26061  1.59926   1.000 18.81911 ? 277  ARG B NH1 1 
ATOM   5574 N  NH2 . ARG B  1 246 ? 28.03396 23.19795  3.59343   1.000 18.08786 ? 277  ARG B NH2 1 
ATOM   5575 N  N   . ARG B  1 247 ? 36.16117 24.06098  3.40181   1.000 20.42145 ? 278  ARG B N   1 
ATOM   5576 C  CA  . ARG B  1 247 ? 36.60898 25.04194  4.38555   1.000 20.18497 ? 278  ARG B CA  1 
ATOM   5577 C  C   . ARG B  1 247 ? 36.85217 26.40104  3.73659   1.000 18.07656 ? 278  ARG B C   1 
ATOM   5578 O  O   . ARG B  1 247 ? 36.42729 27.43349  4.26053   1.000 19.57083 ? 278  ARG B O   1 
ATOM   5579 C  CB  . ARG B  1 247 ? 37.87278 24.55445  5.09714   1.000 21.26280 ? 278  ARG B CB  1 
ATOM   5580 C  CG  . ARG B  1 247 ? 38.33745 25.52628  6.16692   1.000 21.37779 ? 278  ARG B CG  1 
ATOM   5581 C  CD  . ARG B  1 247 ? 39.64788 25.09664  6.80682   1.000 23.29367 ? 278  ARG B CD  1 
ATOM   5582 N  NE  . ARG B  1 247 ? 39.51879 23.84429  7.54173   1.000 23.12341 ? 278  ARG B NE  1 
ATOM   5583 C  CZ  . ARG B  1 247 ? 40.48388 23.32232  8.28607   1.000 26.92754 ? 278  ARG B CZ  1 
ATOM   5584 N  NH1 . ARG B  1 247 ? 41.66237 23.91643  8.40159   1.000 26.11352 ? 278  ARG B NH1 1 
ATOM   5585 N  NH2 . ARG B  1 247 ? 40.25778 22.18429  8.93864   1.000 25.84375 ? 278  ARG B NH2 1 
ATOM   5586 N  N   . THR B  1 248 ? 37.55727 26.42220  2.60160   1.000 19.06504 ? 279  THR B N   1 
ATOM   5587 C  CA  . THR B  1 248 ? 37.78341 27.67543  1.88689   1.000 18.08510 ? 279  THR B CA  1 
ATOM   5588 C  C   . THR B  1 248 ? 36.46530 28.27107  1.41108   1.000 16.92659 ? 279  THR B C   1 
ATOM   5589 O  O   . THR B  1 248 ? 36.21254 29.46986  1.56133   1.000 18.02436 ? 279  THR B O   1 
ATOM   5590 C  CB  . THR B  1 248 ? 38.71130 27.41833  0.69751   1.000 22.01819 ? 279  THR B CB  1 
ATOM   5591 O  OG1 . THR B  1 248 ? 39.90459 26.78170  1.16978   1.000 22.36394 ? 279  THR B OG1 1 
ATOM   5592 C  CG2 . THR B  1 248 ? 39.07371 28.71603  -0.01702  1.000 20.03449 ? 279  THR B CG2 1 
ATOM   5593 N  N   . TYR B  1 249 ? 35.62145 27.43096  0.81600   1.000 18.96128 ? 280  TYR B N   1 
ATOM   5594 C  CA  . TYR B  1 249 ? 34.30780 27.86728  0.35955   1.000 18.71403 ? 280  TYR B CA  1 
ATOM   5595 C  C   . TYR B  1 249 ? 33.49953 28.48473  1.49651   1.000 18.30249 ? 280  TYR B C   1 
ATOM   5596 O  O   . TYR B  1 249 ? 32.88256 29.54775  1.32915   1.000 17.10784 ? 280  TYR B O   1 
ATOM   5597 C  CB  . TYR B  1 249 ? 33.59923 26.65754  -0.24603  1.000 16.56343 ? 280  TYR B CB  1 
ATOM   5598 C  CG  . TYR B  1 249 ? 32.15596 26.83591  -0.64244  1.000 16.63718 ? 280  TYR B CG  1 
ATOM   5599 C  CD1 . TYR B  1 249 ? 31.13795 26.62929  0.28138   1.000 17.37117 ? 280  TYR B CD1 1 
ATOM   5600 C  CD2 . TYR B  1 249 ? 31.81111 27.14843  -1.94801  1.000 18.92171 ? 280  TYR B CD2 1 
ATOM   5601 C  CE1 . TYR B  1 249 ? 29.82004 26.76413  -0.07349  1.000 17.96430 ? 280  TYR B CE1 1 
ATOM   5602 C  CE2 . TYR B  1 249 ? 30.47836 27.27610  -2.31663  1.000 18.50808 ? 280  TYR B CE2 1 
ATOM   5603 C  CZ  . TYR B  1 249 ? 29.49570 27.07710  -1.36565  1.000 17.33661 ? 280  TYR B CZ  1 
ATOM   5604 O  OH  . TYR B  1 249 ? 28.16649 27.18054  -1.71050  1.000 17.89558 ? 280  TYR B OH  1 
ATOM   5605 N  N   . ALA B  1 250 ? 33.48553 27.82242  2.66100   1.000 18.38273 ? 281  ALA B N   1 
ATOM   5606 C  CA  . ALA B  1 250 ? 32.76894 28.35321  3.81501   1.000 19.10975 ? 281  ALA B CA  1 
ATOM   5607 C  C   . ALA B  1 250 ? 33.28012 29.73353  4.19483   1.000 18.06720 ? 281  ALA B C   1 
ATOM   5608 O  O   . ALA B  1 250 ? 32.49209 30.63461  4.49926   1.000 17.51660 ? 281  ALA B O   1 
ATOM   5609 C  CB  . ALA B  1 250 ? 32.90272 27.40941  5.00753   1.000 16.81158 ? 281  ALA B CB  1 
ATOM   5610 N  N   . ALA B  1 251 ? 34.60470 29.91624  4.18653   1.000 18.16625 ? 282  ALA B N   1 
ATOM   5611 C  CA  . ALA B  1 251 ? 35.16612 31.21595  4.51872   1.000 16.74926 ? 282  ALA B CA  1 
ATOM   5612 C  C   . ALA B  1 251 ? 34.78531 32.27540  3.49505   1.000 18.91954 ? 282  ALA B C   1 
ATOM   5613 O  O   . ALA B  1 251 ? 34.63039 33.44934  3.85154   1.000 18.23196 ? 282  ALA B O   1 
ATOM   5614 C  CB  . ALA B  1 251 ? 36.68499 31.09466  4.63265   1.000 18.13177 ? 282  ALA B CB  1 
ATOM   5615 N  N   . MET B  1 252 ? 34.60875 31.88260  2.22772   1.000 17.10215 ? 283  MET B N   1 
ATOM   5616 C  CA  . MET B  1 252 ? 34.18176 32.83854  1.21011   1.000 17.83975 ? 283  MET B CA  1 
ATOM   5617 C  C   . MET B  1 252 ? 32.75627 33.32275  1.46646   1.000 16.22054 ? 283  MET B C   1 
ATOM   5618 O  O   . MET B  1 252 ? 32.46279 34.51706  1.30507   1.000 17.01141 ? 283  MET B O   1 
ATOM   5619 C  CB  . MET B  1 252 ? 34.28370 32.20045  -0.17717  1.000 20.58076 ? 283  MET B CB  1 
ATOM   5620 C  CG  . MET B  1 252 ? 35.71279 31.84819  -0.58365  1.000 19.12584 ? 283  MET B CG  1 
ATOM   5621 S  SD  . MET B  1 252 ? 35.73052 30.80854  -2.04482  1.000 19.76355 ? 283  MET B SD  1 
ATOM   5622 C  CE  . MET B  1 252 ? 35.32536 32.00027  -3.29515  1.000 20.44699 ? 283  MET B CE  1 
ATOM   5623 N  N   . VAL B  1 253 ? 31.86462 32.40529  1.85586   1.000 17.12833 ? 284  VAL B N   1 
ATOM   5624 C  CA  . VAL B  1 253 ? 30.49691 32.77190  2.22437   1.000 16.08981 ? 284  VAL B CA  1 
ATOM   5625 C  C   . VAL B  1 253 ? 30.50534 33.62404  3.48157   1.000 18.71744 ? 284  VAL B C   1 
ATOM   5626 O  O   . VAL B  1 253 ? 29.76543 34.61108  3.59298   1.000 17.28679 ? 284  VAL B O   1 
ATOM   5627 C  CB  . VAL B  1 253 ? 29.64490 31.50129  2.41506   1.000 16.01868 ? 284  VAL B CB  1 
ATOM   5628 C  CG1 . VAL B  1 253 ? 28.23970 31.85645  2.89125   1.000 18.01408 ? 284  VAL B CG1 1 
ATOM   5629 C  CG2 . VAL B  1 253 ? 29.58234 30.68975  1.12694   1.000 16.20907 ? 284  VAL B CG2 1 
ATOM   5630 N  N   . TYR B  1 254 ? 31.35071 33.26117  4.44733   1.000 17.65438 ? 285  TYR B N   1 
ATOM   5631 C  CA  . TYR B  1 254 ? 31.42975 34.03233  5.67981   1.000 17.26720 ? 285  TYR B CA  1 
ATOM   5632 C  C   . TYR B  1 254 ? 31.82595 35.47766  5.40467   1.000 18.94334 ? 285  TYR B C   1 
ATOM   5633 O  O   . TYR B  1 254 ? 31.34188 36.39573  6.07335   1.000 18.69293 ? 285  TYR B O   1 
ATOM   5634 C  CB  . TYR B  1 254 ? 32.41315 33.37173  6.64489   1.000 18.39259 ? 285  TYR B CB  1 
ATOM   5635 C  CG  . TYR B  1 254 ? 32.48460 34.07601  7.97901   1.000 20.60149 ? 285  TYR B CG  1 
ATOM   5636 C  CD1 . TYR B  1 254 ? 31.48621 33.89743  8.93352   1.000 22.60205 ? 285  TYR B CD1 1 
ATOM   5637 C  CD2 . TYR B  1 254 ? 33.53544 34.93023  8.27575   1.000 22.08156 ? 285  TYR B CD2 1 
ATOM   5638 C  CE1 . TYR B  1 254 ? 31.54531 34.55012  10.15274  1.000 26.82533 ? 285  TYR B CE1 1 
ATOM   5639 C  CE2 . TYR B  1 254 ? 33.59813 35.58684  9.48612   1.000 24.63134 ? 285  TYR B CE2 1 
ATOM   5640 C  CZ  . TYR B  1 254 ? 32.60846 35.39228  10.41833  1.000 31.49948 ? 285  TYR B CZ  1 
ATOM   5641 O  OH  . TYR B  1 254 ? 32.68715 36.04995  11.62541  1.000 35.18469 ? 285  TYR B OH  1 
ATOM   5642 N  N   . ALA B  1 255 ? 32.70822 35.70320  4.42469   1.000 16.97380 ? 286  ALA B N   1 
ATOM   5643 C  CA  . ALA B  1 255 ? 33.08753 37.06996  4.08011   1.000 18.81028 ? 286  ALA B CA  1 
ATOM   5644 C  C   . ALA B  1 255 ? 31.89720 37.86461  3.55280   1.000 18.50254 ? 286  ALA B C   1 
ATOM   5645 O  O   . ALA B  1 255 ? 31.77173 39.06401  3.83239   1.000 18.19772 ? 286  ALA B O   1 
ATOM   5646 C  CB  . ALA B  1 255 ? 34.21441 37.05886  3.05039   1.000 18.69437 ? 286  ALA B CB  1 
ATOM   5647 N  N   . VAL B  1 256 ? 31.02686 37.21812  2.76496   1.000 17.53814 ? 287  VAL B N   1 
ATOM   5648 C  CA  . VAL B  1 256 ? 29.77369 37.85789  2.35119   1.000 17.18283 ? 287  VAL B CA  1 
ATOM   5649 C  C   . VAL B  1 256 ? 28.93990 38.20644  3.57465   1.000 19.01865 ? 287  VAL B C   1 
ATOM   5650 O  O   . VAL B  1 256 ? 28.37723 39.30435  3.67845   1.000 19.41284 ? 287  VAL B O   1 
ATOM   5651 C  CB  . VAL B  1 256 ? 28.97872 36.94999  1.39303   1.000 16.18894 ? 287  VAL B CB  1 
ATOM   5652 C  CG1 . VAL B  1 256 ? 27.58089 37.53042  1.15763   1.000 18.33672 ? 287  VAL B CG1 1 
ATOM   5653 C  CG2 . VAL B  1 256 ? 29.69925 36.78310  0.06807   1.000 17.93118 ? 287  VAL B CG2 1 
ATOM   5654 N  N   . ASP B  1 257 ? 28.84093 37.26414  4.51430   1.000 17.98194 ? 288  ASP B N   1 
ATOM   5655 C  CA  . ASP B  1 257 ? 28.04860 37.50311  5.71325   1.000 18.61321 ? 288  ASP B CA  1 
ATOM   5656 C  C   . ASP B  1 257 ? 28.58135 38.69194  6.50775   1.000 20.10874 ? 288  ASP B C   1 
ATOM   5657 O  O   . ASP B  1 257 ? 27.79727 39.51160  7.00352   1.000 18.34061 ? 288  ASP B O   1 
ATOM   5658 C  CB  . ASP B  1 257 ? 28.02153 36.24302  6.56956   1.000 18.41318 ? 288  ASP B CB  1 
ATOM   5659 C  CG  . ASP B  1 257 ? 26.93828 36.29286  7.61998   1.000 18.86483 ? 288  ASP B CG  1 
ATOM   5660 O  OD1 . ASP B  1 257 ? 25.76137 36.11189  7.24302   1.000 20.59900 ? 288  ASP B OD1 1 
ATOM   5661 O  OD2 . ASP B  1 257 ? 27.27090 36.54188  8.80086   1.000 19.41845 ? 288  ASP B OD2 1 
ATOM   5662 N  N   . ARG B  1 258 ? 29.91039 38.79936  6.64772   1.000 17.29973 ? 289  ARG B N   1 
ATOM   5663 C  CA  . ARG B  1 258 ? 30.49661 39.95711  7.32721   1.000 20.03760 ? 289  ARG B CA  1 
ATOM   5664 C  C   . ARG B  1 258 ? 30.09481 41.25381  6.64494   1.000 20.62931 ? 289  ARG B C   1 
ATOM   5665 O  O   . ARG B  1 258 ? 29.75098 42.23984  7.31019   1.000 20.43218 ? 289  ARG B O   1 
ATOM   5666 C  CB  . ARG B  1 258 ? 32.02243 39.86391  7.34633   1.000 19.78724 ? 289  ARG B CB  1 
ATOM   5667 C  CG  . ARG B  1 258 ? 32.62766 38.84864  8.28235   1.000 23.80050 ? 289  ARG B CG  1 
ATOM   5668 C  CD  . ARG B  1 258 ? 34.13892 39.11473  8.40159   1.000 23.49206 ? 289  ARG B CD  1 
ATOM   5669 N  NE  . ARG B  1 258 ? 34.89452 38.76051  7.19815   1.000 21.93288 ? 289  ARG B NE  1 
ATOM   5670 C  CZ  . ARG B  1 258 ? 35.24057 39.61549  6.24409   1.000 21.51570 ? 289  ARG B CZ  1 
ATOM   5671 N  NH1 . ARG B  1 258 ? 34.90155 40.89684  6.30004   1.000 21.64542 ? 289  ARG B NH1 1 
ATOM   5672 N  NH2 . ARG B  1 258 ? 35.94772 39.17933  5.20769   1.000 19.89997 ? 289  ARG B NH2 1 
ATOM   5673 N  N   . GLY B  1 259 ? 30.18951 41.28409  5.31311   1.000 19.59410 ? 290  GLY B N   1 
ATOM   5674 C  CA  . GLY B  1 259 ? 29.83991 42.48924  4.58292   1.000 20.52468 ? 290  GLY B CA  1 
ATOM   5675 C  C   . GLY B  1 259 ? 28.37316 42.84405  4.72256   1.000 20.72387 ? 290  GLY B C   1 
ATOM   5676 O  O   . GLY B  1 259 ? 28.01476 44.02014  4.83365   1.000 19.15387 ? 290  GLY B O   1 
ATOM   5677 N  N   . VAL B  1 260 ? 27.50270 41.83101  4.72050   1.000 18.34737 ? 291  VAL B N   1 
ATOM   5678 C  CA  . VAL B  1 260 ? 26.08192 42.08260  4.94447   1.000 18.24189 ? 291  VAL B CA  1 
ATOM   5679 C  C   . VAL B  1 260 ? 25.86688 42.69344  6.31900   1.000 18.71244 ? 291  VAL B C   1 
ATOM   5680 O  O   . VAL B  1 260 ? 25.06217 43.62015  6.48525   1.000 19.39078 ? 291  VAL B O   1 
ATOM   5681 C  CB  . VAL B  1 260 ? 25.27777 40.78273  4.75672   1.000 18.83106 ? 291  VAL B CB  1 
ATOM   5682 C  CG1 . VAL B  1 260 ? 23.85427 40.93161  5.29903   1.000 20.12337 ? 291  VAL B CG1 1 
ATOM   5683 C  CG2 . VAL B  1 260 ? 25.24305 40.42469  3.27850   1.000 19.99327 ? 291  VAL B CG2 1 
ATOM   5684 N  N   . GLY B  1 261 ? 26.60015 42.20925  7.32331   1.000 18.28252 ? 292  GLY B N   1 
ATOM   5685 C  CA  . GLY B  1 261 ? 26.46856 42.79128  8.64925   1.000 19.85021 ? 292  GLY B CA  1 
ATOM   5686 C  C   . GLY B  1 261 ? 26.84224 44.26159  8.68349   1.000 21.65924 ? 292  GLY B C   1 
ATOM   5687 O  O   . GLY B  1 261 ? 26.18032 45.06335  9.34900   1.000 20.74850 ? 292  GLY B O   1 
ATOM   5688 N  N   . LYS B  1 262 ? 27.91017 44.63451  7.97158   1.000 20.22470 ? 293  LYS B N   1 
ATOM   5689 C  CA  . LYS B  1 262 ? 28.31381 46.03841  7.91851   1.000 20.57923 ? 293  LYS B CA  1 
ATOM   5690 C  C   . LYS B  1 262 ? 27.30380 46.86807  7.13644   1.000 20.30122 ? 293  LYS B C   1 
ATOM   5691 O  O   . LYS B  1 262 ? 27.04468 48.03353  7.47794   1.000 22.44360 ? 293  LYS B O   1 
ATOM   5692 C  CB  . LYS B  1 262 ? 29.70580 46.15419  7.29657   1.000 21.84297 ? 293  LYS B CB  1 
ATOM   5693 N  N   . ILE B  1 263 ? 26.73630 46.28570  6.07574   1.000 18.95012 ? 294  ILE B N   1 
ATOM   5694 C  CA  . ILE B  1 263 ? 25.70209 46.96154  5.29892   1.000 20.56642 ? 294  ILE B CA  1 
ATOM   5695 C  C   . ILE B  1 263 ? 24.48497 47.23721  6.17069   1.000 22.63180 ? 294  ILE B C   1 
ATOM   5696 O  O   . ILE B  1 263 ? 23.91575 48.33380  6.14373   1.000 21.20080 ? 294  ILE B O   1 
ATOM   5697 C  CB  . ILE B  1 263 ? 25.33151 46.11595  4.06671   1.000 19.40691 ? 294  ILE B CB  1 
ATOM   5698 C  CG1 . ILE B  1 263 ? 26.44776 46.21087  3.02782   1.000 19.10931 ? 294  ILE B CG1 1 
ATOM   5699 C  CG2 . ILE B  1 263 ? 23.97463 46.55133  3.48941   1.000 19.55144 ? 294  ILE B CG2 1 
ATOM   5700 C  CD1 . ILE B  1 263 ? 26.41934 45.07611  2.00715   1.000 21.19542 ? 294  ILE B CD1 1 
ATOM   5701 N  N   . VAL B  1 264 ? 24.06954 46.23887  6.95377   1.000 18.88090 ? 295  VAL B N   1 
ATOM   5702 C  CA  . VAL B  1 264 ? 22.92733 46.40657  7.85382   1.000 18.89579 ? 295  VAL B CA  1 
ATOM   5703 C  C   . VAL B  1 264 ? 23.20759 47.50992  8.86626   1.000 22.54280 ? 295  VAL B C   1 
ATOM   5704 O  O   . VAL B  1 264 ? 22.34720 48.36026  9.13946   1.000 21.50534 ? 295  VAL B O   1 
ATOM   5705 C  CB  . VAL B  1 264 ? 22.59300 45.07191  8.55367   1.000 19.20928 ? 295  VAL B CB  1 
ATOM   5706 C  CG1 . VAL B  1 264 ? 21.67098 45.30569  9.74623   1.000 21.75247 ? 295  VAL B CG1 1 
ATOM   5707 C  CG2 . VAL B  1 264 ? 21.94618 44.07906  7.57778   1.000 21.72910 ? 295  VAL B CG2 1 
ATOM   5708 N  N   . GLN B  1 265 ? 24.41409 47.52414  9.43661   1.000 19.57155 ? 296  GLN B N   1 
ATOM   5709 C  CA  . GLN B  1 265 ? 24.73268 48.58414  10.39256  1.000 20.43666 ? 296  GLN B CA  1 
ATOM   5710 C  C   . GLN B  1 265 ? 24.64941 49.95931  9.73732   1.000 25.28272 ? 296  GLN B C   1 
ATOM   5711 O  O   . GLN B  1 265 ? 24.16298 50.92184  10.34980  1.000 24.26397 ? 296  GLN B O   1 
ATOM   5712 C  CB  . GLN B  1 265 ? 26.11855 48.35460  11.00029  1.000 26.51539 ? 296  GLN B CB  1 
ATOM   5713 C  CG  . GLN B  1 265 ? 26.41817 49.28505  12.17319  1.000 34.52242 ? 296  GLN B CG  1 
ATOM   5714 C  CD  . GLN B  1 265 ? 25.34213 49.23847  13.25597  1.000 45.46646 ? 296  GLN B CD  1 
ATOM   5715 O  OE1 . GLN B  1 265 ? 24.79789 48.17456  13.57179  1.000 47.02857 ? 296  GLN B OE1 1 
ATOM   5716 N  NE2 . GLN B  1 265 ? 25.02450 50.40179  13.82307  1.000 46.77600 ? 296  GLN B NE2 1 
ATOM   5717 N  N   . THR B  1 266 ? 25.10387 50.06627  8.48480   1.000 22.33744 ? 297  THR B N   1 
ATOM   5718 C  CA  . THR B  1 266 ? 25.01390 51.32578  7.75390   1.000 20.94976 ? 297  THR B CA  1 
ATOM   5719 C  C   . THR B  1 266 ? 23.56140 51.72522  7.51224   1.000 23.33274 ? 297  THR B C   1 
ATOM   5720 O  O   . THR B  1 266 ? 23.19702 52.89890  7.66240   1.000 24.12886 ? 297  THR B O   1 
ATOM   5721 C  CB  . THR B  1 266 ? 25.76427 51.21394  6.42731   1.000 24.33505 ? 297  THR B CB  1 
ATOM   5722 O  OG1 . THR B  1 266 ? 27.13653 50.88161  6.68238   1.000 23.61747 ? 297  THR B OG1 1 
ATOM   5723 C  CG2 . THR B  1 266 ? 25.70574 52.54031  5.66240   1.000 24.21686 ? 297  THR B CG2 1 
ATOM   5724 N  N   . LEU B  1 267 ? 22.71609 50.76520  7.13180   1.000 20.35937 ? 298  LEU B N   1 
ATOM   5725 C  CA  . LEU B  1 267 ? 21.30232 51.07566  6.92294   1.000 19.39333 ? 298  LEU B CA  1 
ATOM   5726 C  C   . LEU B  1 267 ? 20.64503 51.55773  8.20714   1.000 22.69302 ? 298  LEU B C   1 
ATOM   5727 O  O   . LEU B  1 267 ? 19.78483 52.44592  8.17367   1.000 21.66175 ? 298  LEU B O   1 
ATOM   5728 C  CB  . LEU B  1 267 ? 20.56528 49.84922  6.37902   1.000 20.47026 ? 298  LEU B CB  1 
ATOM   5729 C  CG  . LEU B  1 267 ? 20.91401 49.46095  4.93911   1.000 21.57386 ? 298  LEU B CG  1 
ATOM   5730 C  CD1 . LEU B  1 267 ? 20.38475 48.07177  4.63363   1.000 21.27166 ? 298  LEU B CD1 1 
ATOM   5731 C  CD2 . LEU B  1 267 ? 20.32910 50.48748  3.96377   1.000 21.96626 ? 298  LEU B CD2 1 
ATOM   5732 N  N   . LYS B  1 268 ? 21.02954 50.98338  9.34710   1.000 20.13586 ? 299  LYS B N   1 
ATOM   5733 C  CA  . LYS B  1 268 ? 20.47822 51.44912  10.61592  1.000 24.73285 ? 299  LYS B CA  1 
ATOM   5734 C  C   . LYS B  1 268 ? 20.96681 52.85289  10.93962  1.000 28.77333 ? 299  LYS B C   1 
ATOM   5735 O  O   . LYS B  1 268 ? 20.18638 53.69814  11.39632  1.000 27.55998 ? 299  LYS B O   1 
ATOM   5736 C  CB  . LYS B  1 268 ? 20.83901 50.48490  11.74174  1.000 23.13969 ? 299  LYS B CB  1 
ATOM   5737 C  CG  . LYS B  1 268 ? 20.09884 49.16020  11.63949  1.000 24.29162 ? 299  LYS B CG  1 
ATOM   5738 C  CD  . LYS B  1 268 ? 20.53967 48.18021  12.70901  1.000 25.43146 ? 299  LYS B CD  1 
ATOM   5739 C  CE  . LYS B  1 268 ? 19.80789 46.86232  12.56092  1.000 28.36989 ? 299  LYS B CE  1 
ATOM   5740 N  NZ  . LYS B  1 268 ? 20.29419 45.88797  13.57491  1.000 35.80198 ? 299  LYS B NZ  1 
ATOM   5741 N  N   . GLU B  1 269 ? 22.24871 53.12490  10.69459  1.000 24.65987 ? 300  GLU B N   1 
ATOM   5742 C  CA  . GLU B  1 269 ? 22.79547 54.43288  11.04216  1.000 25.19275 ? 300  GLU B CA  1 
ATOM   5743 C  C   . GLU B  1 269 ? 22.19706 55.53417  10.17760  1.000 27.43680 ? 300  GLU B C   1 
ATOM   5744 O  O   . GLU B  1 269 ? 21.95303 56.64743  10.66519  1.000 27.53036 ? 300  GLU B O   1 
ATOM   5745 C  CB  . GLU B  1 269 ? 24.32294 54.39715  10.93674  1.000 24.85609 ? 300  GLU B CB  1 
ATOM   5746 C  CG  . GLU B  1 269 ? 24.93485 53.50667  12.01234  1.000 32.50568 ? 300  GLU B CG  1 
ATOM   5747 C  CD  . GLU B  1 269 ? 26.43629 53.30972  11.87158  1.000 38.29548 ? 300  GLU B CD  1 
ATOM   5748 O  OE1 . GLU B  1 269 ? 27.01705 53.75269  10.85679  1.000 43.71239 ? 300  GLU B OE1 1 
ATOM   5749 O  OE2 . GLU B  1 269 ? 27.03270 52.70454  12.78849  1.000 37.23419 ? 300  GLU B OE2 1 
ATOM   5750 N  N   . THR B  1 270 ? 21.93059 55.24257  8.90280   1.000 23.09061 ? 301  THR B N   1 
ATOM   5751 C  CA  . THR B  1 270 ? 21.32633 56.21917  8.00379   1.000 25.52792 ? 301  THR B CA  1 
ATOM   5752 C  C   . THR B  1 270 ? 19.80863 56.25949  8.11490   1.000 24.90333 ? 301  THR B C   1 
ATOM   5753 O  O   . THR B  1 270 ? 19.17190 57.02365  7.37809   1.000 28.40958 ? 301  THR B O   1 
ATOM   5754 C  CB  . THR B  1 270 ? 21.70545 55.93300  6.54490   1.000 26.81140 ? 301  THR B CB  1 
ATOM   5755 O  OG1 . THR B  1 270 ? 21.23259 54.62755  6.17653   1.000 27.42012 ? 301  THR B OG1 1 
ATOM   5756 C  CG2 . THR B  1 270 ? 23.21331 56.00649  6.33259   1.000 27.38583 ? 301  THR B CG2 1 
ATOM   5757 N  N   . LYS B  1 271 ? 19.22528 55.45329  9.00307   1.000 23.45177 ? 302  LYS B N   1 
ATOM   5758 C  CA  . LYS B  1 271 ? 17.77413 55.35393  9.17243   1.000 26.43233 ? 302  LYS B CA  1 
ATOM   5759 C  C   . LYS B  1 271 ? 17.07368 54.91706  7.88612   1.000 25.82636 ? 302  LYS B C   1 
ATOM   5760 O  O   . LYS B  1 271 ? 15.90736 55.24027  7.65543   1.000 27.38900 ? 302  LYS B O   1 
ATOM   5761 C  CB  . LYS B  1 271 ? 17.19564 56.66791  9.70045   1.000 31.16917 ? 302  LYS B CB  1 
ATOM   5762 C  CG  . LYS B  1 271 ? 17.69143 56.99420  11.10246  1.000 34.33356 ? 302  LYS B CG  1 
ATOM   5763 C  CD  . LYS B  1 271 ? 17.03529 58.24749  11.63914  1.000 46.92647 ? 302  LYS B CD  1 
ATOM   5764 C  CE  . LYS B  1 271 ? 16.88305 58.18067  13.14882  1.000 51.80073 ? 302  LYS B CE  1 
ATOM   5765 N  NZ  . LYS B  1 271 ? 15.73390 59.01714  13.60252  1.000 59.46486 ? 302  LYS B NZ  1 
ATOM   5766 N  N   . GLN B  1 272 ? 17.77514 54.16061  7.04199   1.000 22.59625 ? 303  GLN B N   1 
ATOM   5767 C  CA  . GLN B  1 272 ? 17.18149 53.58603  5.84251   1.000 22.54291 ? 303  GLN B CA  1 
ATOM   5768 C  C   . GLN B  1 272 ? 16.69456 52.15320  6.05392   1.000 20.90682 ? 303  GLN B C   1 
ATOM   5769 O  O   . GLN B  1 272 ? 15.92301 51.64882  5.22644   1.000 23.73161 ? 303  GLN B O   1 
ATOM   5770 C  CB  . GLN B  1 272 ? 18.19247 53.62410  4.68231   1.000 21.64435 ? 303  GLN B CB  1 
ATOM   5771 C  CG  . GLN B  1 272 ? 18.44827 55.02579  4.06717   1.000 25.92211 ? 303  GLN B CG  1 
ATOM   5772 C  CD  . GLN B  1 272 ? 19.73577 55.08080  3.23151   1.000 31.88773 ? 303  GLN B CD  1 
ATOM   5773 O  OE1 . GLN B  1 272 ? 20.82136 54.85823  3.75963   1.000 30.11108 ? 303  GLN B OE1 1 
ATOM   5774 N  NE2 . GLN B  1 272 ? 19.61718 55.37978  1.93090   1.000 29.49517 ? 303  GLN B NE2 1 
ATOM   5775 N  N   . PHE B  1 273 ? 17.08107 51.51846  7.16514   1.000 20.67319 ? 304  PHE B N   1 
ATOM   5776 C  CA  . PHE B  1 273 ? 16.88244 50.08023  7.35862   1.000 21.06749 ? 304  PHE B CA  1 
ATOM   5777 C  C   . PHE B  1 273 ? 15.40593 49.69196  7.32610   1.000 21.25181 ? 304  PHE B C   1 
ATOM   5778 O  O   . PHE B  1 273 ? 15.01805 48.71850  6.66835   1.000 21.18605 ? 304  PHE B O   1 
ATOM   5779 C  CB  . PHE B  1 273 ? 17.51602 49.67228  8.68972   1.000 20.55587 ? 304  PHE B CB  1 
ATOM   5780 C  CG  . PHE B  1 273 ? 17.57431 48.18988  8.92647   1.000 21.91314 ? 304  PHE B CG  1 
ATOM   5781 C  CD1 . PHE B  1 273 ? 18.30038 47.36483  8.08006   1.000 23.36130 ? 304  PHE B CD1 1 
ATOM   5782 C  CD2 . PHE B  1 273 ? 16.95954 47.62949  10.03962  1.000 26.55859 ? 304  PHE B CD2 1 
ATOM   5783 C  CE1 . PHE B  1 273 ? 18.37943 46.00208  8.31586   1.000 25.00309 ? 304  PHE B CE1 1 
ATOM   5784 C  CE2 . PHE B  1 273 ? 17.03888 46.25937  10.28364  1.000 25.53663 ? 304  PHE B CE2 1 
ATOM   5785 C  CZ  . PHE B  1 273 ? 17.76098 45.45349  9.42560   1.000 23.26721 ? 304  PHE B CZ  1 
ATOM   5786 N  N   . ASP B  1 274 ? 14.56465 50.43931  8.04023   1.000 20.78656 ? 305  ASP B N   1 
ATOM   5787 C  CA  . ASP B  1 274 ? 13.17286 50.03169  8.19646   1.000 21.65071 ? 305  ASP B CA  1 
ATOM   5788 C  C   . ASP B  1 274 ? 12.43998 49.98557  6.85558   1.000 20.27544 ? 305  ASP B C   1 
ATOM   5789 O  O   . ASP B  1 274 ? 11.59083 49.11134  6.63409   1.000 20.55009 ? 305  ASP B O   1 
ATOM   5790 C  CB  . ASP B  1 274 ? 12.47471 50.98391  9.16948   1.000 20.97188 ? 305  ASP B CB  1 
ATOM   5791 C  CG  . ASP B  1 274 ? 10.99332 50.68384  9.32849   1.000 32.25636 ? 305  ASP B CG  1 
ATOM   5792 O  OD1 . ASP B  1 274 ? 10.66043 49.70332  10.02406  1.000 34.70827 ? 305  ASP B OD1 1 
ATOM   5793 O  OD2 . ASP B  1 274 ? 10.16283 51.44507  8.77244   1.000 36.69850 ? 305  ASP B OD2 1 
ATOM   5794 N  N   . ASN B  1 275 ? 12.74716 50.90968  5.94773   1.000 19.12073 ? 306  ASN B N   1 
ATOM   5795 C  CA  . ASN B  1 275 ? 12.08096 50.96706  4.65218   1.000 20.98086 ? 306  ASN B CA  1 
ATOM   5796 C  C   . ASN B  1 275 ? 13.03032 50.58520  3.52458   1.000 19.63449 ? 306  ASN B C   1 
ATOM   5797 O  O   . ASN B  1 275 ? 13.02805 51.19461  2.45525   1.000 19.48293 ? 306  ASN B O   1 
ATOM   5798 C  CB  . ASN B  1 275 ? 11.48039 52.34512  4.38761   1.000 21.56702 ? 306  ASN B CB  1 
ATOM   5799 C  CG  . ASN B  1 275 ? 10.39569 52.30394  3.33411   1.000 22.89345 ? 306  ASN B CG  1 
ATOM   5800 O  OD1 . ASN B  1 275 ? 9.74309  51.27056  3.13597   1.000 22.07026 ? 306  ASN B OD1 1 
ATOM   5801 N  ND2 . ASN B  1 275 ? 10.20340 53.42053  2.63823   1.000 23.12641 ? 306  ASN B ND2 1 
ATOM   5802 N  N   . THR B  1 276 ? 13.86611 49.58042  3.76537   1.000 18.91455 ? 307  THR B N   1 
ATOM   5803 C  CA  . THR B  1 276 ? 14.62843 48.92988  2.70959   1.000 18.49972 ? 307  THR B CA  1 
ATOM   5804 C  C   . THR B  1 276 ? 14.12530 47.50363  2.56650   1.000 15.72867 ? 307  THR B C   1 
ATOM   5805 O  O   . THR B  1 276 ? 14.02681 46.78065  3.56287   1.000 18.36621 ? 307  THR B O   1 
ATOM   5806 C  CB  . THR B  1 276 ? 16.12527 48.91805  3.02521   1.000 18.83900 ? 307  THR B CB  1 
ATOM   5807 O  OG1 . THR B  1 276 ? 16.61063 50.26326  3.08583   1.000 19.45504 ? 307  THR B OG1 1 
ATOM   5808 C  CG2 . THR B  1 276 ? 16.90001 48.16320  1.94050   1.000 19.49604 ? 307  THR B CG2 1 
ATOM   5809 N  N   . LEU B  1 277 ? 13.81929 47.10283  1.33858   1.000 16.52266 ? 308  LEU B N   1 
ATOM   5810 C  CA  . LEU B  1 277 ? 13.58263 45.69847  1.02111   1.000 15.74008 ? 308  LEU B CA  1 
ATOM   5811 C  C   . LEU B  1 277 ? 14.91696 45.07963  0.62598   1.000 18.45552 ? 308  LEU B C   1 
ATOM   5812 O  O   . LEU B  1 277 ? 15.49904 45.46605  -0.39103  1.000 18.56973 ? 308  LEU B O   1 
ATOM   5813 C  CB  . LEU B  1 277 ? 12.56967 45.55426  -0.11009  1.000 16.79422 ? 308  LEU B CB  1 
ATOM   5814 C  CG  . LEU B  1 277 ? 12.42845 44.14541  -0.70389  1.000 18.81882 ? 308  LEU B CG  1 
ATOM   5815 C  CD1 . LEU B  1 277 ? 11.96421 43.11330  0.33152   1.000 19.60058 ? 308  LEU B CD1 1 
ATOM   5816 C  CD2 . LEU B  1 277 ? 11.48953 44.17020  -1.90140  1.000 19.49024 ? 308  LEU B CD2 1 
ATOM   5817 N  N   . ILE B  1 278 ? 15.41493 44.14721  1.43938   1.000 17.30180 ? 309  ILE B N   1 
ATOM   5818 C  CA  . ILE B  1 278 ? 16.61362 43.38117  1.11313   1.000 16.84421 ? 309  ILE B CA  1 
ATOM   5819 C  C   . ILE B  1 278 ? 16.16627 42.03526  0.57102   1.000 17.75971 ? 309  ILE B C   1 
ATOM   5820 O  O   . ILE B  1 278 ? 15.40899 41.31036  1.23166   1.000 16.83633 ? 309  ILE B O   1 
ATOM   5821 C  CB  . ILE B  1 278 ? 17.53239 43.19670  2.33180   1.000 17.29709 ? 309  ILE B CB  1 
ATOM   5822 C  CG1 . ILE B  1 278 ? 17.95318 44.54756  2.92068   1.000 16.66359 ? 309  ILE B CG1 1 
ATOM   5823 C  CG2 . ILE B  1 278 ? 18.77346 42.38531  1.93856   1.000 18.99524 ? 309  ILE B CG2 1 
ATOM   5824 C  CD1 . ILE B  1 278 ? 18.73862 44.40017  4.23697   1.000 19.35332 ? 309  ILE B CD1 1 
ATOM   5825 N  N   . VAL B  1 279 ? 16.61985 41.69731  -0.63340  1.000 16.80141 ? 310  VAL B N   1 
ATOM   5826 C  CA  . VAL B  1 279 ? 16.35382 40.40577  -1.24221  1.000 16.03744 ? 310  VAL B CA  1 
ATOM   5827 C  C   . VAL B  1 279 ? 17.69441 39.70298  -1.40319  1.000 16.71009 ? 310  VAL B C   1 
ATOM   5828 O  O   . VAL B  1 279 ? 18.58296 40.21864  -2.08543  1.000 17.89776 ? 310  VAL B O   1 
ATOM   5829 C  CB  . VAL B  1 279 ? 15.65007 40.53732  -2.60306  1.000 16.91690 ? 310  VAL B CB  1 
ATOM   5830 C  CG1 . VAL B  1 279 ? 15.52147 39.15692  -3.24771  1.000 17.93522 ? 310  VAL B CG1 1 
ATOM   5831 C  CG2 . VAL B  1 279 ? 14.27949 41.22088  -2.45026  1.000 17.15135 ? 310  VAL B CG2 1 
ATOM   5832 N  N   . PHE B  1 280 ? 17.84383 38.54514  -0.77311  1.000 14.99676 ? 311  PHE B N   1 
ATOM   5833 C  CA  . PHE B  1 280 ? 19.06760 37.76165  -0.86300  1.000 17.00564 ? 311  PHE B CA  1 
ATOM   5834 C  C   . PHE B  1 280 ? 18.77942 36.48023  -1.63013  1.000 15.93198 ? 311  PHE B C   1 
ATOM   5835 O  O   . PHE B  1 280 ? 17.79058 35.80335  -1.34552  1.000 16.37556 ? 311  PHE B O   1 
ATOM   5836 C  CB  . PHE B  1 280 ? 19.59017 37.42461  0.53569   1.000 16.59097 ? 311  PHE B CB  1 
ATOM   5837 C  CG  . PHE B  1 280 ? 20.74175 36.45602  0.53099   1.000 16.78605 ? 311  PHE B CG  1 
ATOM   5838 C  CD1 . PHE B  1 280 ? 22.02436 36.90138  0.27674   1.000 19.79537 ? 311  PHE B CD1 1 
ATOM   5839 C  CD2 . PHE B  1 280 ? 20.53888 35.10887  0.79526   1.000 17.82980 ? 311  PHE B CD2 1 
ATOM   5840 C  CE1 . PHE B  1 280 ? 23.09687 36.01190  0.26492   1.000 19.40368 ? 311  PHE B CE1 1 
ATOM   5841 C  CE2 . PHE B  1 280 ? 21.60823 34.21492  0.78868   1.000 19.57404 ? 311  PHE B CE2 1 
ATOM   5842 C  CZ  . PHE B  1 280 ? 22.88368 34.67752  0.52228   1.000 20.23650 ? 311  PHE B CZ  1 
ATOM   5843 N  N   . LEU B  1 281 ? 19.64603 36.13151  -2.58392  1.000 16.40179 ? 312  LEU B N   1 
ATOM   5844 C  CA  . LEU B  1 281 ? 19.48716 34.86475  -3.29175  1.000 15.02009 ? 312  LEU B CA  1 
ATOM   5845 C  C   . LEU B  1 281 ? 20.80090 34.50344  -3.97120  1.000 16.47605 ? 312  LEU B C   1 
ATOM   5846 O  O   . LEU B  1 281 ? 21.76948 35.26486  -3.94859  1.000 17.22807 ? 312  LEU B O   1 
ATOM   5847 C  CB  . LEU B  1 281 ? 18.33610 34.91143  -4.32166  1.000 15.29014 ? 312  LEU B CB  1 
ATOM   5848 C  CG  . LEU B  1 281 ? 18.55910 35.67896  -5.63516  1.000 17.50385 ? 312  LEU B CG  1 
ATOM   5849 C  CD1 . LEU B  1 281 ? 17.48375 35.32017  -6.64762  1.000 18.37832 ? 312  LEU B CD1 1 
ATOM   5850 C  CD2 . LEU B  1 281 ? 18.59473 37.17378  -5.43388  1.000 17.22122 ? 312  LEU B CD2 1 
ATOM   5851 N  N   . SER B  1 282 ? 20.82314 33.30892  -4.55275  1.000 15.34039 ? 313  SER B N   1 
ATOM   5852 C  CA  . SER B  1 282 ? 21.92695 32.86964  -5.39436  1.000 14.29296 ? 313  SER B CA  1 
ATOM   5853 C  C   . SER B  1 282 ? 21.47364 32.91216  -6.84642  1.000 15.04883 ? 313  SER B C   1 
ATOM   5854 O  O   . SER B  1 282 ? 20.28256 32.77131  -7.13456  1.000 16.82724 ? 313  SER B O   1 
ATOM   5855 C  CB  . SER B  1 282 ? 22.36457 31.45095  -5.01506  1.000 16.67542 ? 313  SER B CB  1 
ATOM   5856 O  OG  . SER B  1 282 ? 23.42668 31.00035  -5.85257  1.000 16.33097 ? 313  SER B OG  1 
ATOM   5857 N  N   . ASP B  1 283 ? 22.42966 33.07226  -7.77061  1.000 14.56788 ? 314  ASP B N   1 
ATOM   5858 C  CA  . ASP B  1 283 ? 22.06142 33.08334  -9.18501  1.000 15.54443 ? 314  ASP B CA  1 
ATOM   5859 C  C   . ASP B  1 283 ? 21.79582 31.69408  -9.75213  1.000 17.19812 ? 314  ASP B C   1 
ATOM   5860 O  O   . ASP B  1 283 ? 21.17710 31.58367  -10.81369 1.000 16.73221 ? 314  ASP B O   1 
ATOM   5861 C  CB  . ASP B  1 283 ? 23.13083 33.79914  -10.02596 1.000 16.52934 ? 314  ASP B CB  1 
ATOM   5862 C  CG  . ASP B  1 283 ? 24.43022 33.01390  -10.16437 1.000 17.15054 ? 314  ASP B CG  1 
ATOM   5863 O  OD1 . ASP B  1 283 ? 24.77196 32.16197  -9.31310  1.000 18.09542 ? 314  ASP B OD1 1 
ATOM   5864 O  OD2 . ASP B  1 283 ? 25.14743 33.26729  -11.15938 1.000 18.40488 ? 314  ASP B OD2 1 
ATOM   5865 N  N   . ASN B  1 284 ? 22.23201 30.64245  -9.07281  1.000 16.18517 ? 315  ASN B N   1 
ATOM   5866 C  CA  . ASN B  1 284 ? 21.95888 29.26654  -9.47546  1.000 14.98506 ? 315  ASN B CA  1 
ATOM   5867 C  C   . ASN B  1 284 ? 22.40770 28.36209  -8.33082  1.000 13.96020 ? 315  ASN B C   1 
ATOM   5868 O  O   . ASN B  1 284 ? 22.91199 28.83830  -7.30722  1.000 14.57848 ? 315  ASN B O   1 
ATOM   5869 C  CB  . ASN B  1 284 ? 22.65204 28.90806  -10.80205 1.000 15.67759 ? 315  ASN B CB  1 
ATOM   5870 C  CG  . ASN B  1 284 ? 24.15215 29.22118  -10.80865 1.000 16.59518 ? 315  ASN B CG  1 
ATOM   5871 O  OD1 . ASN B  1 284 ? 24.60779 30.11869  -11.53055 1.000 16.62709 ? 315  ASN B OD1 1 
ATOM   5872 N  ND2 . ASN B  1 284 ? 24.92951 28.47120  -10.02620 1.000 15.36087 ? 315  ASN B ND2 1 
ATOM   5873 N  N   . GLY B  1 285 ? 22.20778 27.05744  -8.51478  1.000 15.89114 ? 316  GLY B N   1 
ATOM   5874 C  CA  . GLY B  1 285 ? 22.58151 26.08699  -7.50337  1.000 14.89034 ? 316  GLY B CA  1 
ATOM   5875 C  C   . GLY B  1 285 ? 24.08134 26.00774  -7.29723  1.000 15.55277 ? 316  GLY B C   1 
ATOM   5876 O  O   . GLY B  1 285 ? 24.88576 26.48271  -8.10058  1.000 16.02044 ? 316  GLY B O   1 
ATOM   5877 N  N   . GLY B  1 286 ? 24.47502 25.40069  -6.18180  1.000 16.68376 ? 317  GLY B N   1 
ATOM   5878 C  CA  . GLY B  1 286 ? 25.89401 25.22351  -5.91703  1.000 16.57273 ? 317  GLY B CA  1 
ATOM   5879 C  C   . GLY B  1 286 ? 26.51455 24.20017  -6.84963  1.000 14.96095 ? 317  GLY B C   1 
ATOM   5880 O  O   . GLY B  1 286 ? 25.86218 23.27187  -7.32623  1.000 15.34150 ? 317  GLY B O   1 
ATOM   5881 N  N   . ASN B  1 287 ? 27.80311 24.39179  -7.12888  1.000 15.68937 ? 318  ASN B N   1 
ATOM   5882 C  CA  . ASN B  1 287 ? 28.58207 23.42349  -7.88448  1.000 15.33314 ? 318  ASN B CA  1 
ATOM   5883 C  C   . ASN B  1 287 ? 29.21629 22.47667  -6.87096  1.000 16.12632 ? 318  ASN B C   1 
ATOM   5884 O  O   . ASN B  1 287 ? 30.13327 22.87325  -6.13837  1.000 15.80620 ? 318  ASN B O   1 
ATOM   5885 C  CB  . ASN B  1 287 ? 29.63809 24.13409  -8.73660  1.000 17.17877 ? 318  ASN B CB  1 
ATOM   5886 C  CG  . ASN B  1 287 ? 30.41119 23.17120  -9.62991  1.000 16.98393 ? 318  ASN B CG  1 
ATOM   5887 O  OD1 . ASN B  1 287 ? 30.56163 21.99303  -9.30778  1.000 18.07514 ? 318  ASN B OD1 1 
ATOM   5888 N  ND2 . ASN B  1 287 ? 30.91220 23.67653  -10.76266 1.000 19.33378 ? 318  ASN B ND2 1 
ATOM   5889 N  N   . PHE B  1 288 ? 28.70935 21.24171  -6.79096  1.000 15.07552 ? 319  PHE B N   1 
ATOM   5890 C  CA  . PHE B  1 288 ? 29.19723 20.37436  -5.72234  1.000 16.16025 ? 319  PHE B CA  1 
ATOM   5891 C  C   . PHE B  1 288 ? 30.57757 19.78611  -6.01138  1.000 18.18172 ? 319  PHE B C   1 
ATOM   5892 O  O   . PHE B  1 288 ? 31.09137 19.01220  -5.19479  1.000 20.16397 ? 319  PHE B O   1 
ATOM   5893 C  CB  . PHE B  1 288 ? 28.14868 19.29370  -5.34587  1.000 17.16368 ? 319  PHE B CB  1 
ATOM   5894 C  CG  . PHE B  1 288 ? 27.69474 18.35560  -6.46161  1.000 18.13420 ? 319  PHE B CG  1 
ATOM   5895 C  CD1 . PHE B  1 288 ? 28.45585 18.09810  -7.58562  1.000 19.74023 ? 319  PHE B CD1 1 
ATOM   5896 C  CD2 . PHE B  1 288 ? 26.48514 17.67319  -6.31645  1.000 18.46353 ? 319  PHE B CD2 1 
ATOM   5897 C  CE1 . PHE B  1 288 ? 28.00115 17.19347  -8.55763  1.000 19.45288 ? 319  PHE B CE1 1 
ATOM   5898 C  CE2 . PHE B  1 288 ? 26.02888 16.77894  -7.27282  1.000 19.12367 ? 319  PHE B CE2 1 
ATOM   5899 C  CZ  . PHE B  1 288 ? 26.79037 16.53298  -8.39528  1.000 18.89705 ? 319  PHE B CZ  1 
ATOM   5900 N  N   . ASN B  1 289 ? 31.20445 20.17403  -7.11646  1.000 16.02115 ? 320  ASN B N   1 
ATOM   5901 C  CA  . ASN B  1 289 ? 32.61579 19.87345  -7.33821  1.000 16.43586 ? 320  ASN B CA  1 
ATOM   5902 C  C   . ASN B  1 289 ? 33.54717 20.86080  -6.64586  1.000 19.44721 ? 320  ASN B C   1 
ATOM   5903 O  O   . ASN B  1 289 ? 34.74186 20.57180  -6.50722  1.000 19.84238 ? 320  ASN B O   1 
ATOM   5904 C  CB  . ASN B  1 289 ? 32.92223 19.87450  -8.83506  1.000 17.52447 ? 320  ASN B CB  1 
ATOM   5905 C  CG  . ASN B  1 289 ? 32.20556 18.77426  -9.56820  1.000 20.47107 ? 320  ASN B CG  1 
ATOM   5906 O  OD1 . ASN B  1 289 ? 32.15556 17.64615  -9.10115  1.000 20.62742 ? 320  ASN B OD1 1 
ATOM   5907 N  ND2 . ASN B  1 289 ? 31.62918 19.10140  -10.71515 1.000 26.82517 ? 320  ASN B ND2 1 
ATOM   5908 N  N   . HIS B  1 290 ? 33.04180 22.01376  -6.22027  1.000 16.25761 ? 321  HIS B N   1 
ATOM   5909 C  CA  . HIS B  1 290 ? 33.88309 23.11665  -5.75212  1.000 17.16417 ? 321  HIS B CA  1 
ATOM   5910 C  C   . HIS B  1 290 ? 33.34979 23.68917  -4.45016  1.000 17.97208 ? 321  HIS B C   1 
ATOM   5911 O  O   . HIS B  1 290 ? 33.18348 24.90351  -4.29668  1.000 21.86472 ? 321  HIS B O   1 
ATOM   5912 C  CB  . HIS B  1 290 ? 33.99360 24.20235  -6.81437  1.000 19.93431 ? 321  HIS B CB  1 
ATOM   5913 C  CG  . HIS B  1 290 ? 34.65237 23.73015  -8.06647  1.000 20.85517 ? 321  HIS B CG  1 
ATOM   5914 N  ND1 . HIS B  1 290 ? 35.97175 23.32908  -8.09888  1.000 26.24331 ? 321  HIS B ND1 1 
ATOM   5915 C  CD2 . HIS B  1 290 ? 34.16760 23.54316  -9.31675  1.000 22.95859 ? 321  HIS B CD2 1 
ATOM   5916 C  CE1 . HIS B  1 290 ? 36.27520 22.93019  -9.32235  1.000 28.66932 ? 321  HIS B CE1 1 
ATOM   5917 N  NE2 . HIS B  1 290 ? 35.19917 23.05079  -10.08033 1.000 27.65291 ? 321  HIS B NE2 1 
ATOM   5918 N  N   . GLY B  1 291 ? 33.06152 22.79896  -3.50322  1.000 17.93020 ? 322  GLY B N   1 
ATOM   5919 C  CA  . GLY B  1 291 ? 32.81616 23.14292  -2.11926  1.000 19.69237 ? 322  GLY B CA  1 
ATOM   5920 C  C   . GLY B  1 291 ? 31.35711 23.17832  -1.71494  1.000 18.09426 ? 322  GLY B C   1 
ATOM   5921 O  O   . GLY B  1 291 ? 31.06482 23.15362  -0.51673  1.000 20.78596 ? 322  GLY B O   1 
ATOM   5922 N  N   . ALA B  1 292 ? 30.44039 23.26257  -2.66927  1.000 17.39497 ? 323  ALA B N   1 
ATOM   5923 C  CA  . ALA B  1 292 ? 29.04904 23.55249  -2.34646  1.000 16.54503 ? 323  ALA B CA  1 
ATOM   5924 C  C   . ALA B  1 292 ? 28.27996 22.28551  -1.98457  1.000 16.96141 ? 323  ALA B C   1 
ATOM   5925 O  O   . ALA B  1 292 ? 28.65444 21.16947  -2.34688  1.000 18.47297 ? 323  ALA B O   1 
ATOM   5926 C  CB  . ALA B  1 292 ? 28.35520 24.24849  -3.51951  1.000 18.21422 ? 323  ALA B CB  1 
ATOM   5927 N  N   . ASN B  1 293 ? 27.17200 22.48862  -1.27145  1.000 15.44224 ? 324  ASN B N   1 
ATOM   5928 C  CA  . ASN B  1 293 ? 26.27964 21.41357  -0.84820  1.000 18.33264 ? 324  ASN B CA  1 
ATOM   5929 C  C   . ASN B  1 293 ? 24.84690 21.86650  -1.09102  1.000 16.27084 ? 324  ASN B C   1 
ATOM   5930 O  O   . ASN B  1 293 ? 24.44066 22.92798  -0.60264  1.000 17.37479 ? 324  ASN B O   1 
ATOM   5931 C  CB  . ASN B  1 293 ? 26.51393 21.08658  0.63292   1.000 17.75489 ? 324  ASN B CB  1 
ATOM   5932 C  CG  . ASN B  1 293 ? 25.78700 19.83764  1.08768   1.000 26.56868 ? 324  ASN B CG  1 
ATOM   5933 O  OD1 . ASN B  1 293 ? 24.69955 19.53347  0.61981   1.000 22.47511 ? 324  ASN B OD1 1 
ATOM   5934 N  ND2 . ASN B  1 293 ? 26.39719 19.10350  2.01421   1.000 30.39681 ? 324  ASN B ND2 1 
ATOM   5935 N  N   . ASN B  1 294 ? 24.09177 21.09417  -1.87671  1.000 15.92293 ? 325  ASN B N   1 
ATOM   5936 C  CA  . ASN B  1 294 ? 22.71895 21.46527  -2.21486  1.000 16.06515 ? 325  ASN B CA  1 
ATOM   5937 C  C   . ASN B  1 294 ? 21.68187 20.63554  -1.47335  1.000 16.82087 ? 325  ASN B C   1 
ATOM   5938 O  O   . ASN B  1 294 ? 20.51683 20.63055  -1.87451  1.000 16.80329 ? 325  ASN B O   1 
ATOM   5939 C  CB  . ASN B  1 294 ? 22.47189 21.34717  -3.71984  1.000 17.32108 ? 325  ASN B CB  1 
ATOM   5940 C  CG  . ASN B  1 294 ? 23.33595 22.28910  -4.51992  1.000 15.43542 ? 325  ASN B CG  1 
ATOM   5941 O  OD1 . ASN B  1 294 ? 23.51809 23.44123  -4.14004  1.000 15.21739 ? 325  ASN B OD1 1 
ATOM   5942 N  ND2 . ASN B  1 294 ? 23.91384 21.78604  -5.61967  1.000 16.67481 ? 325  ASN B ND2 1 
ATOM   5943 N  N   . TYR B  1 295 ? 22.07541 19.95389  -0.40153  1.000 17.57500 ? 326  TYR B N   1 
ATOM   5944 C  CA  . TYR B  1 295 ? 21.15363 19.12181  0.36423   1.000 17.61516 ? 326  TYR B CA  1 
ATOM   5945 C  C   . TYR B  1 295 ? 19.88979 19.90138  0.73229   1.000 17.22083 ? 326  TYR B C   1 
ATOM   5946 O  O   . TYR B  1 295 ? 19.97691 21.06155  1.14881   1.000 16.78693 ? 326  TYR B O   1 
ATOM   5947 C  CB  . TYR B  1 295 ? 21.84081 18.62970  1.64301   1.000 19.34564 ? 326  TYR B CB  1 
ATOM   5948 C  CG  . TYR B  1 295 ? 20.96808 17.72857  2.48726   1.000 20.02877 ? 326  TYR B CG  1 
ATOM   5949 C  CD1 . TYR B  1 295 ? 20.92071 16.35899  2.24483   1.000 21.72759 ? 326  TYR B CD1 1 
ATOM   5950 C  CD2 . TYR B  1 295 ? 20.19011 18.24841  3.51920   1.000 19.84268 ? 326  TYR B CD2 1 
ATOM   5951 C  CE1 . TYR B  1 295 ? 20.11669 15.52983  3.00803   1.000 26.70003 ? 326  TYR B CE1 1 
ATOM   5952 C  CE2 . TYR B  1 295 ? 19.38624 17.42401  4.28492   1.000 24.58263 ? 326  TYR B CE2 1 
ATOM   5953 C  CZ  . TYR B  1 295 ? 19.35899 16.07310  4.02637   1.000 27.37379 ? 326  TYR B CZ  1 
ATOM   5954 O  OH  . TYR B  1 295 ? 18.55822 15.24798  4.78729   1.000 33.62043 ? 326  TYR B OH  1 
ATOM   5955 N  N   . PRO B  1 296 ? 18.69851 19.29109  0.63184   1.000 16.07273 ? 327  PRO B N   1 
ATOM   5956 C  CA  . PRO B  1 296 ? 18.38111 17.91130  0.25961   1.000 17.46151 ? 327  PRO B CA  1 
ATOM   5957 C  C   . PRO B  1 296 ? 18.08105 17.71918  -1.22002  1.000 18.95947 ? 327  PRO B C   1 
ATOM   5958 O  O   . PRO B  1 296 ? 17.43873 16.73296  -1.59549  1.000 17.51228 ? 327  PRO B O   1 
ATOM   5959 C  CB  . PRO B  1 296 ? 17.12365 17.63746  1.09349   1.000 17.65472 ? 327  PRO B CB  1 
ATOM   5960 C  CG  . PRO B  1 296 ? 16.38735 18.95888  0.96949   1.000 16.95194 ? 327  PRO B CG  1 
ATOM   5961 C  CD  . PRO B  1 296 ? 17.48365 20.01787  1.05574   1.000 17.56271 ? 327  PRO B CD  1 
ATOM   5962 N  N   . LEU B  1 297 ? 18.50231 18.65518  -2.06328  1.000 15.88389 ? 328  LEU B N   1 
ATOM   5963 C  CA  . LEU B  1 297 ? 18.18084 18.60161  -3.48039  1.000 14.70028 ? 328  LEU B CA  1 
ATOM   5964 C  C   . LEU B  1 297 ? 19.14626 17.69532  -4.21672  1.000 15.53582 ? 328  LEU B C   1 
ATOM   5965 O  O   . LEU B  1 297 ? 20.30907 17.54684  -3.83254  1.000 18.05058 ? 328  LEU B O   1 
ATOM   5966 C  CB  . LEU B  1 297 ? 18.24049 19.99560  -4.10741  1.000 14.37252 ? 328  LEU B CB  1 
ATOM   5967 C  CG  . LEU B  1 297 ? 17.53690 21.13272  -3.36306  1.000 14.77919 ? 328  LEU B CG  1 
ATOM   5968 C  CD1 . LEU B  1 297 ? 17.66958 22.45378  -4.15471  1.000 15.13836 ? 328  LEU B CD1 1 
ATOM   5969 C  CD2 . LEU B  1 297 ? 16.06006 20.79184  -3.10783  1.000 17.67190 ? 328  LEU B CD2 1 
ATOM   5970 N  N   . LYS B  1 298 ? 18.64805 17.09638  -5.29273  1.000 15.00074 ? 329  LYS B N   1 
ATOM   5971 C  CA  . LYS B  1 298 ? 19.48588 16.32342  -6.19472  1.000 16.31007 ? 329  LYS B CA  1 
ATOM   5972 C  C   . LYS B  1 298 ? 20.21521 17.26111  -7.15052  1.000 15.52775 ? 329  LYS B C   1 
ATOM   5973 O  O   . LYS B  1 298 ? 19.67490 18.28680  -7.57756  1.000 15.18762 ? 329  LYS B O   1 
ATOM   5974 C  CB  . LYS B  1 298 ? 18.63560 15.32976  -6.98558  1.000 16.43166 ? 329  LYS B CB  1 
ATOM   5975 C  CG  . LYS B  1 298 ? 19.43096 14.48434  -8.01166  1.000 16.24319 ? 329  LYS B CG  1 
ATOM   5976 C  CD  . LYS B  1 298 ? 18.50168 13.53657  -8.78016  1.000 18.55186 ? 329  LYS B CD  1 
ATOM   5977 C  CE  . LYS B  1 298 ? 18.13095 12.33455  -7.95246  1.000 19.96542 ? 329  LYS B CE  1 
ATOM   5978 N  NZ  . LYS B  1 298 ? 17.27065 11.41074  -8.75965  1.000 19.39216 ? 329  LYS B NZ  1 
ATOM   5979 N  N   . GLY B  1 299 ? 21.45216 16.92550  -7.46530  1.000 15.58516 ? 330  GLY B N   1 
ATOM   5980 C  CA  . GLY B  1 299 ? 22.11673 17.59620  -8.56399  1.000 15.40584 ? 330  GLY B CA  1 
ATOM   5981 C  C   . GLY B  1 299 ? 22.93764 18.80458  -8.16770  1.000 15.80765 ? 330  GLY B C   1 
ATOM   5982 O  O   . GLY B  1 299 ? 23.18151 19.12128  -6.99285  1.000 15.93340 ? 330  GLY B O   1 
ATOM   5983 N  N   . THR B  1 300 ? 23.33831 19.52409  -9.21343  1.000 15.46940 ? 331  THR B N   1 
ATOM   5984 C  CA  . THR B  1 300 ? 24.38542 20.51723  -9.10750  1.000 16.87471 ? 331  THR B CA  1 
ATOM   5985 C  C   . THR B  1 300 ? 24.10043 21.62730  -10.10690 1.000 17.72665 ? 331  THR B C   1 
ATOM   5986 O  O   . THR B  1 300 ? 23.24990 21.49587  -10.99613 1.000 16.32236 ? 331  THR B O   1 
ATOM   5987 C  CB  . THR B  1 300 ? 25.75737 19.85916  -9.34717  1.000 15.05899 ? 331  THR B CB  1 
ATOM   5988 O  OG1 . THR B  1 300 ? 26.80949 20.81112  -9.15945  1.000 17.03022 ? 331  THR B OG1 1 
ATOM   5989 C  CG2 . THR B  1 300 ? 25.84817 19.28803  -10.76539 1.000 16.94842 ? 331  THR B CG2 1 
ATOM   5990 N  N   . LYS B  1 301 ? 24.83782 22.71887  -9.94955  1.000 16.61916 ? 332  LYS B N   1 
ATOM   5991 C  CA  . LYS B  1 301 ? 24.81250 23.83630  -10.88884 1.000 16.60406 ? 332  LYS B CA  1 
ATOM   5992 C  C   . LYS B  1 301 ? 24.71717 23.34073  -12.32782 1.000 16.96721 ? 332  LYS B C   1 
ATOM   5993 O  O   . LYS B  1 301 ? 25.46149 22.44693  -12.73924 1.000 16.24660 ? 332  LYS B O   1 
ATOM   5994 C  CB  . LYS B  1 301 ? 26.08531 24.65953  -10.69699 1.000 15.78112 ? 332  LYS B CB  1 
ATOM   5995 C  CG  . LYS B  1 301 ? 26.30581 25.74376  -11.75665 1.000 14.35564 ? 332  LYS B CG  1 
ATOM   5996 C  CD  . LYS B  1 301 ? 27.67864 26.36537  -11.55967 1.000 14.02637 ? 332  LYS B CD  1 
ATOM   5997 C  CE  . LYS B  1 301 ? 27.95141 27.43466  -12.62243 1.000 17.04097 ? 332  LYS B CE  1 
ATOM   5998 N  NZ  . LYS B  1 301 ? 29.37156 27.92785  -12.47840 1.000 20.24827 ? 332  LYS B NZ  1 
ATOM   5999 N  N   . GLY B  1 302 ? 23.78123 23.91876  -13.08172 1.000 16.01655 ? 333  GLY B N   1 
ATOM   6000 C  CA  . GLY B  1 302 ? 23.59723 23.58118  -14.48142 1.000 16.91263 ? 333  GLY B CA  1 
ATOM   6001 C  C   . GLY B  1 302 ? 22.56189 22.50655  -14.75672 1.000 17.07771 ? 333  GLY B C   1 
ATOM   6002 O  O   . GLY B  1 302 ? 22.12568 22.37615  -15.90939 1.000 16.38728 ? 333  GLY B O   1 
ATOM   6003 N  N   . ASP B  1 303 ? 22.16165 21.72805  -13.74780 1.000 15.68111 ? 334  ASP B N   1 
ATOM   6004 C  CA  . ASP B  1 303 ? 21.15200 20.68714  -13.92402 1.000 16.98279 ? 334  ASP B CA  1 
ATOM   6005 C  C   . ASP B  1 303 ? 19.74073 21.27292  -13.91481 1.000 15.57120 ? 334  ASP B C   1 
ATOM   6006 O  O   . ASP B  1 303 ? 19.49813 22.36988  -13.40655 1.000 16.02070 ? 334  ASP B O   1 
ATOM   6007 C  CB  . ASP B  1 303 ? 21.19502 19.63861  -12.80354 1.000 16.82944 ? 334  ASP B CB  1 
ATOM   6008 C  CG  . ASP B  1 303 ? 22.48881 18.85054  -12.75130 1.000 17.06047 ? 334  ASP B CG  1 
ATOM   6009 O  OD1 . ASP B  1 303 ? 23.24561 18.82090  -13.73713 1.000 17.94838 ? 334  ASP B OD1 1 
ATOM   6010 O  OD2 . ASP B  1 303 ? 22.72998 18.21879  -11.70185 1.000 16.01248 ? 334  ASP B OD2 1 
ATOM   6011 N  N   . THR B  1 304 ? 18.78877 20.49873  -14.45704 1.000 15.64088 ? 335  THR B N   1 
ATOM   6012 C  CA  . THR B  1 304 ? 17.37984 20.79937  -14.22975 1.000 14.90707 ? 335  THR B CA  1 
ATOM   6013 C  C   . THR B  1 304 ? 16.76000 19.93040  -13.14252 1.000 15.84271 ? 335  THR B C   1 
ATOM   6014 O  O   . THR B  1 304 ? 15.54639 20.01364  -12.92167 1.000 17.16887 ? 335  THR B O   1 
ATOM   6015 C  CB  . THR B  1 304 ? 16.55407 20.67525  -15.51202 1.000 16.29152 ? 335  THR B CB  1 
ATOM   6016 O  OG1 . THR B  1 304 ? 16.70913 19.36560  -16.06537 1.000 15.99007 ? 335  THR B OG1 1 
ATOM   6017 C  CG2 . THR B  1 304 ? 16.95607 21.77860  -16.52409 1.000 17.95788 ? 335  THR B CG2 1 
ATOM   6018 N  N   . TRP B  1 305 ? 17.55700 19.10982  -12.45465 1.000 15.12852 ? 336  TRP B N   1 
ATOM   6019 C  CA  . TRP B  1 305 ? 17.17019 18.71976  -11.10406 1.000 14.69445 ? 336  TRP B CA  1 
ATOM   6020 C  C   . TRP B  1 305 ? 17.01779 19.97532  -10.25363 1.000 16.13229 ? 336  TRP B C   1 
ATOM   6021 O  O   . TRP B  1 305 ? 17.56464 21.02552  -10.56891 1.000 16.28725 ? 336  TRP B O   1 
ATOM   6022 C  CB  . TRP B  1 305 ? 18.23217 17.84341  -10.45264 1.000 15.27196 ? 336  TRP B CB  1 
ATOM   6023 C  CG  . TRP B  1 305 ? 18.61793 16.59326  -11.16168 1.000 15.01777 ? 336  TRP B CG  1 
ATOM   6024 C  CD1 . TRP B  1 305 ? 19.85768 16.27996  -11.65863 1.000 17.66181 ? 336  TRP B CD1 1 
ATOM   6025 C  CD2 . TRP B  1 305 ? 17.78690 15.45739  -11.41537 1.000 15.47695 ? 336  TRP B CD2 1 
ATOM   6026 N  NE1 . TRP B  1 305 ? 19.84163 15.02153  -12.21426 1.000 16.23217 ? 336  TRP B NE1 1 
ATOM   6027 C  CE2 . TRP B  1 305 ? 18.58318 14.49335  -12.07757 1.000 16.13226 ? 336  TRP B CE2 1 
ATOM   6028 C  CE3 . TRP B  1 305 ? 16.44823 15.16408  -11.15448 1.000 16.89998 ? 336  TRP B CE3 1 
ATOM   6029 C  CZ2 . TRP B  1 305 ? 18.08053 13.25686  -12.48519 1.000 15.22038 ? 336  TRP B CZ2 1 
ATOM   6030 C  CZ3 . TRP B  1 305 ? 15.94515 13.93392  -11.55572 1.000 17.27637 ? 336  TRP B CZ3 1 
ATOM   6031 C  CH2 . TRP B  1 305 ? 16.76285 12.99018  -12.21275 1.000 17.40781 ? 336  TRP B CH2 1 
ATOM   6032 N  N   . GLU B  1 306 ? 16.30309 19.85392  -9.13251  1.000 16.33090 ? 337  GLU B N   1 
ATOM   6033 C  CA  . GLU B  1 306 ? 16.12328 21.01602  -8.25954  1.000 16.00751 ? 337  GLU B CA  1 
ATOM   6034 C  C   . GLU B  1 306 ? 17.45296 21.67357  -7.89052  1.000 16.56129 ? 337  GLU B C   1 
ATOM   6035 O  O   . GLU B  1 306 ? 17.53373 22.89716  -7.77690  1.000 16.29949 ? 337  GLU B O   1 
ATOM   6036 C  CB  . GLU B  1 306 ? 15.39231 20.61730  -6.97984  1.000 14.48258 ? 337  GLU B CB  1 
ATOM   6037 C  CG  . GLU B  1 306 ? 13.96603 20.13451  -7.18660  1.000 17.14186 ? 337  GLU B CG  1 
ATOM   6038 C  CD  . GLU B  1 306 ? 13.02396 21.24126  -7.62913  1.000 16.12881 ? 337  GLU B CD  1 
ATOM   6039 O  OE1 . GLU B  1 306 ? 12.91803 21.49441  -8.84812  1.000 17.90949 ? 337  GLU B OE1 1 
ATOM   6040 O  OE2 . GLU B  1 306 ? 12.38229 21.85673  -6.74736  1.000 17.44041 ? 337  GLU B OE2 1 
ATOM   6041 N  N   . GLY B  1 307 ? 18.49620 20.87467  -7.67003  1.000 15.59159 ? 338  GLY B N   1 
ATOM   6042 C  CA  . GLY B  1 307 ? 19.77154 21.42267  -7.23616  1.000 15.65919 ? 338  GLY B CA  1 
ATOM   6043 C  C   . GLY B  1 307 ? 20.40066 22.41614  -8.19680  1.000 15.40296 ? 338  GLY B C   1 
ATOM   6044 O  O   . GLY B  1 307 ? 21.26296 23.19342  -7.78819  1.000 14.94282 ? 338  GLY B O   1 
ATOM   6045 N  N   . GLY B  1 308 ? 20.00064 22.40259  -9.47092  1.000 15.81252 ? 339  GLY B N   1 
ATOM   6046 C  CA  . GLY B  1 308 ? 20.55770 23.36100  -10.40936 1.000 16.50377 ? 339  GLY B CA  1 
ATOM   6047 C  C   . GLY B  1 308 ? 19.98368 24.76112  -10.31030 1.000 14.92888 ? 339  GLY B C   1 
ATOM   6048 O  O   . GLY B  1 308 ? 20.69623 25.73788  -10.57070 1.000 15.67057 ? 339  GLY B O   1 
ATOM   6049 N  N   . TYR B  1 309 ? 18.69687 24.89917  -9.94372  1.000 15.73358 ? 340  TYR B N   1 
ATOM   6050 C  CA  . TYR B  1 309 ? 18.09355 26.22238  -10.03696 1.000 15.93211 ? 340  TYR B CA  1 
ATOM   6051 C  C   . TYR B  1 309 ? 17.10888 26.55059  -8.92053  1.000 15.98671 ? 340  TYR B C   1 
ATOM   6052 O  O   . TYR B  1 309 ? 16.44169 27.58447  -8.99754  1.000 15.71792 ? 340  TYR B O   1 
ATOM   6053 C  CB  . TYR B  1 309 ? 17.41126 26.42050  -11.40675 1.000 16.53276 ? 340  TYR B CB  1 
ATOM   6054 C  CG  . TYR B  1 309 ? 16.24292 25.50298  -11.72575 1.000 15.60452 ? 340  TYR B CG  1 
ATOM   6055 C  CD1 . TYR B  1 309 ? 16.44306 24.15552  -12.04489 1.000 16.56825 ? 340  TYR B CD1 1 
ATOM   6056 C  CD2 . TYR B  1 309 ? 14.94697 26.00271  -11.75325 1.000 15.40530 ? 340  TYR B CD2 1 
ATOM   6057 C  CE1 . TYR B  1 309 ? 15.36946 23.31845  -12.36610 1.000 17.89865 ? 340  TYR B CE1 1 
ATOM   6058 C  CE2 . TYR B  1 309 ? 13.86511 25.17141  -12.06740 1.000 17.00831 ? 340  TYR B CE2 1 
ATOM   6059 C  CZ  . TYR B  1 309 ? 14.08928 23.84420  -12.37549 1.000 17.38903 ? 340  TYR B CZ  1 
ATOM   6060 O  OH  . TYR B  1 309 ? 13.02261 23.02446  -12.68987 1.000 19.52669 ? 340  TYR B OH  1 
ATOM   6061 N  N   . ARG B  1 310 ? 17.00326 25.72331  -7.88842  1.000 14.90448 ? 341  ARG B N   1 
ATOM   6062 C  CA  . ARG B  1 310 ? 16.30300 26.10454  -6.67173  1.000 15.43209 ? 341  ARG B CA  1 
ATOM   6063 C  C   . ARG B  1 310 ? 17.34344 26.63943  -5.69818  1.000 14.24060 ? 341  ARG B C   1 
ATOM   6064 O  O   . ARG B  1 310 ? 18.36039 25.98376  -5.46523  1.000 16.24483 ? 341  ARG B O   1 
ATOM   6065 C  CB  . ARG B  1 310 ? 15.55520 24.89817  -6.10250  1.000 15.20065 ? 341  ARG B CB  1 
ATOM   6066 C  CG  . ARG B  1 310 ? 14.64290 25.16858  -4.92170  1.000 14.50039 ? 341  ARG B CG  1 
ATOM   6067 C  CD  . ARG B  1 310 ? 13.88120 23.89523  -4.61791  1.000 15.76846 ? 341  ARG B CD  1 
ATOM   6068 N  NE  . ARG B  1 310 ? 13.10607 23.95835  -3.38424  1.000 15.88003 ? 341  ARG B NE  1 
ATOM   6069 C  CZ  . ARG B  1 310 ? 12.14112 23.09980  -3.07727  1.000 17.63686 ? 341  ARG B CZ  1 
ATOM   6070 N  NH1 . ARG B  1 310 ? 11.76896 22.14543  -3.92035  1.000 16.72114 ? 341  ARG B NH1 1 
ATOM   6071 N  NH2 . ARG B  1 310 ? 11.53925 23.19528  -1.89131  1.000 17.59570 ? 341  ARG B NH2 1 
ATOM   6072 N  N   . VAL B  1 311 ? 17.10547 27.83782  -5.16556  1.000 15.15592 ? 342  VAL B N   1 
ATOM   6073 C  CA  . VAL B  1 311 ? 18.15481 28.59644  -4.48350  1.000 15.79903 ? 342  VAL B CA  1 
ATOM   6074 C  C   . VAL B  1 311 ? 17.62452 29.10296  -3.14846  1.000 16.23520 ? 342  VAL B C   1 
ATOM   6075 O  O   . VAL B  1 311 ? 16.40472 29.23617  -2.95432  1.000 15.85089 ? 342  VAL B O   1 
ATOM   6076 C  CB  . VAL B  1 311 ? 18.65907 29.78028  -5.34770  1.000 16.27043 ? 342  VAL B CB  1 
ATOM   6077 C  CG1 . VAL B  1 311 ? 19.23027 29.27735  -6.66270  1.000 16.96023 ? 342  VAL B CG1 1 
ATOM   6078 C  CG2 . VAL B  1 311 ? 17.55666 30.81525  -5.59292  1.000 16.82336 ? 342  VAL B CG2 1 
ATOM   6079 N  N   . PRO B  1 312 ? 18.51538 29.41024  -2.20860  1.000 15.28882 ? 343  PRO B N   1 
ATOM   6080 C  CA  . PRO B  1 312 ? 18.07418 30.10430  -0.99257  1.000 16.67765 ? 343  PRO B CA  1 
ATOM   6081 C  C   . PRO B  1 312 ? 17.59013 31.49430  -1.34866  1.000 17.32648 ? 343  PRO B C   1 
ATOM   6082 O  O   . PRO B  1 312 ? 18.12186 32.13722  -2.25783  1.000 16.43041 ? 343  PRO B O   1 
ATOM   6083 C  CB  . PRO B  1 312 ? 19.33978 30.17156  -0.12163  1.000 16.78545 ? 343  PRO B CB  1 
ATOM   6084 C  CG  . PRO B  1 312 ? 20.29777 29.16677  -0.75440  1.000 17.48401 ? 343  PRO B CG  1 
ATOM   6085 C  CD  . PRO B  1 312 ? 19.96966 29.20350  -2.21893  1.000 17.98214 ? 343  PRO B CD  1 
ATOM   6086 N  N   . MET B  1 313 ? 16.58472 31.96906  -0.61154  1.000 15.58444 ? 344  MET B N   1 
ATOM   6087 C  CA  . MET B  1 313 ? 16.14522 33.34455  -0.80656  1.000 16.06759 ? 344  MET B CA  1 
ATOM   6088 C  C   . MET B  1 313 ? 15.37462 33.82304  0.41277   1.000 18.32444 ? 344  MET B C   1 
ATOM   6089 O  O   . MET B  1 313 ? 14.58460 33.07419  0.98519   1.000 16.17977 ? 344  MET B O   1 
ATOM   6090 C  CB  . MET B  1 313 ? 15.26934 33.49850  -2.06087  1.000 17.19721 ? 344  MET B CB  1 
ATOM   6091 C  CG  . MET B  1 313 ? 14.80670 34.95819  -2.30224  1.000 15.94429 ? 344  MET B CG  1 
ATOM   6092 S  SD  . MET B  1 313 ? 14.12976 35.30505  -3.94497  1.000 19.60219 ? 344  MET B SD  1 
ATOM   6093 C  CE  . MET B  1 313 ? 12.45996 34.74185  -3.69234  1.000 17.08140 ? 344  MET B CE  1 
ATOM   6094 N  N   . PHE B  1 314 ? 15.60925 35.07020  0.80208   1.000 17.15420 ? 345  PHE B N   1 
ATOM   6095 C  CA  . PHE B  1 314 ? 14.71732 35.72904  1.74753   1.000 15.66486 ? 345  PHE B CA  1 
ATOM   6096 C  C   . PHE B  1 314 ? 14.39926 37.14621  1.27529   1.000 16.99781 ? 345  PHE B C   1 
ATOM   6097 O  O   . PHE B  1 314 ? 15.12463 37.74660  0.47794   1.000 15.52367 ? 345  PHE B O   1 
ATOM   6098 C  CB  . PHE B  1 314 ? 15.28441 35.73519  3.19909   1.000 16.34241 ? 345  PHE B CB  1 
ATOM   6099 C  CG  . PHE B  1 314 ? 16.54031 36.56737  3.39484   1.000 17.77418 ? 345  PHE B CG  1 
ATOM   6100 C  CD1 . PHE B  1 314 ? 16.48667 37.96351  3.41614   1.000 17.44677 ? 345  PHE B CD1 1 
ATOM   6101 C  CD2 . PHE B  1 314 ? 17.76323 35.94721  3.63214   1.000 16.20358 ? 345  PHE B CD2 1 
ATOM   6102 C  CE1 . PHE B  1 314 ? 17.63167 38.73250  3.61852   1.000 18.32408 ? 345  PHE B CE1 1 
ATOM   6103 C  CE2 . PHE B  1 314 ? 18.91760 36.71225  3.83521   1.000 15.78681 ? 345  PHE B CE2 1 
ATOM   6104 C  CZ  . PHE B  1 314 ? 18.85219 38.10268  3.83001   1.000 16.46105 ? 345  PHE B CZ  1 
ATOM   6105 N  N   . PHE B  1 315 ? 13.27114 37.65928  1.76606   1.000 16.95196 ? 346  PHE B N   1 
ATOM   6106 C  CA  . PHE B  1 315 ? 12.91073 39.07163  1.67739   1.000 15.97427 ? 346  PHE B CA  1 
ATOM   6107 C  C   . PHE B  1 315 ? 12.94007 39.62725  3.08958   1.000 17.32119 ? 346  PHE B C   1 
ATOM   6108 O  O   . PHE B  1 315 ? 12.33692 39.03702  3.99108   1.000 19.28513 ? 346  PHE B O   1 
ATOM   6109 C  CB  . PHE B  1 315 ? 11.48541 39.29110  1.14512   1.000 18.34107 ? 346  PHE B CB  1 
ATOM   6110 C  CG  . PHE B  1 315 ? 11.28417 39.11676  -0.34309  1.000 19.08855 ? 346  PHE B CG  1 
ATOM   6111 C  CD1 . PHE B  1 315 ? 12.22273 38.51921  -1.17826  1.000 16.88720 ? 346  PHE B CD1 1 
ATOM   6112 C  CD2 . PHE B  1 315 ? 10.08493 39.55975  -0.89653  1.000 20.24919 ? 346  PHE B CD2 1 
ATOM   6113 C  CE1 . PHE B  1 315 ? 11.96096 38.36853  -2.55185  1.000 18.14264 ? 346  PHE B CE1 1 
ATOM   6114 C  CE2 . PHE B  1 315 ? 9.81513  39.42449  -2.24994  1.000 19.27406 ? 346  PHE B CE2 1 
ATOM   6115 C  CZ  . PHE B  1 315 ? 10.75394 38.82136  -3.09057  1.000 18.45341 ? 346  PHE B CZ  1 
ATOM   6116 N  N   . HIS B  1 316 ? 13.59889 40.76582  3.28303   1.000 16.26450 ? 347  HIS B N   1 
ATOM   6117 C  CA  . HIS B  1 316 ? 13.64420 41.42091  4.58517   1.000 17.62891 ? 347  HIS B CA  1 
ATOM   6118 C  C   . HIS B  1 316 ? 13.24902 42.87348  4.38817   1.000 18.55417 ? 347  HIS B C   1 
ATOM   6119 O  O   . HIS B  1 316 ? 13.89133 43.58780  3.61787   1.000 19.36158 ? 347  HIS B O   1 
ATOM   6120 C  CB  . HIS B  1 316 ? 15.04306 41.31670  5.20549   1.000 17.41598 ? 347  HIS B CB  1 
ATOM   6121 C  CG  . HIS B  1 316 ? 15.19272 42.05640  6.49991   1.000 18.07888 ? 347  HIS B CG  1 
ATOM   6122 N  ND1 . HIS B  1 316 ? 15.54571 43.38615  6.55687   1.000 18.32046 ? 347  HIS B ND1 1 
ATOM   6123 C  CD2 . HIS B  1 316 ? 15.07259 41.64076  7.78331   1.000 18.36201 ? 347  HIS B CD2 1 
ATOM   6124 C  CE1 . HIS B  1 316 ? 15.61677 43.76555  7.81999   1.000 20.33711 ? 347  HIS B CE1 1 
ATOM   6125 N  NE2 . HIS B  1 316 ? 15.33684 42.72408  8.58523   1.000 20.52080 ? 347  HIS B NE2 1 
ATOM   6126 N  N   . TRP B  1 317 ? 12.18653 43.30449  5.07293   1.000 17.85230 ? 348  TRP B N   1 
ATOM   6127 C  CA  . TRP B  1 317 ? 11.64719 44.64679  4.90063   1.000 19.90618 ? 348  TRP B CA  1 
ATOM   6128 C  C   . TRP B  1 317 ? 10.86049 44.97150  6.15999   1.000 20.02314 ? 348  TRP B C   1 
ATOM   6129 O  O   . TRP B  1 317 ? 9.67182  44.65920  6.23359   1.000 21.00872 ? 348  TRP B O   1 
ATOM   6130 C  CB  . TRP B  1 317 ? 10.76153 44.70717  3.65366   1.000 19.75708 ? 348  TRP B CB  1 
ATOM   6131 C  CG  . TRP B  1 317 ? 10.22001 46.07048  3.30009   1.000 20.38373 ? 348  TRP B CG  1 
ATOM   6132 C  CD1 . TRP B  1 317 ? 10.65300 47.28110  3.75435   1.000 18.74482 ? 348  TRP B CD1 1 
ATOM   6133 C  CD2 . TRP B  1 317 ? 9.12936  46.33978  2.41259   1.000 18.85994 ? 348  TRP B CD2 1 
ATOM   6134 N  NE1 . TRP B  1 317 ? 9.89701  48.29988  3.18976   1.000 19.57908 ? 348  TRP B NE1 1 
ATOM   6135 C  CE2 . TRP B  1 317 ? 8.95819  47.74214  2.36391   1.000 19.09664 ? 348  TRP B CE2 1 
ATOM   6136 C  CE3 . TRP B  1 317 ? 8.27324  45.52797  1.65887   1.000 20.13745 ? 348  TRP B CE3 1 
ATOM   6137 C  CZ2 . TRP B  1 317 ? 7.96532  48.34739  1.58586   1.000 21.93460 ? 348  TRP B CZ2 1 
ATOM   6138 C  CZ3 . TRP B  1 317 ? 7.30007  46.12529  0.88331   1.000 22.87549 ? 348  TRP B CZ3 1 
ATOM   6139 C  CH2 . TRP B  1 317 ? 7.14901  47.52469  0.85648   1.000 21.65001 ? 348  TRP B CH2 1 
ATOM   6140 N  N   . PRO B  1 318 ? 11.49712 45.54930  7.17921   1.000 20.16372 ? 349  PRO B N   1 
ATOM   6141 C  CA  . PRO B  1 318 ? 10.84679 45.61091  8.50176   1.000 20.23554 ? 349  PRO B CA  1 
ATOM   6142 C  C   . PRO B  1 318 ? 9.51430  46.34095  8.50208   1.000 21.40455 ? 349  PRO B C   1 
ATOM   6143 O  O   . PRO B  1 318 ? 8.62055  45.97232  9.27528   1.000 22.61429 ? 349  PRO B O   1 
ATOM   6144 C  CB  . PRO B  1 318 ? 11.89300 46.32868  9.36408   1.000 22.92774 ? 349  PRO B CB  1 
ATOM   6145 C  CG  . PRO B  1 318 ? 13.23034 45.95593  8.69892   1.000 20.76560 ? 349  PRO B CG  1 
ATOM   6146 C  CD  . PRO B  1 318 ? 12.90260 45.99796  7.22061   1.000 20.95391 ? 349  PRO B CD  1 
ATOM   6147 N  N   . LYS B  1 319 ? 9.34318  47.34436  7.63887   1.000 19.37110 ? 350  LYS B N   1 
ATOM   6148 C  CA  . LYS B  1 319 ? 8.10032  48.11046  7.64922   1.000 21.78871 ? 350  LYS B CA  1 
ATOM   6149 C  C   . LYS B  1 319 ? 6.88726  47.23973  7.34019   1.000 23.40398 ? 350  LYS B C   1 
ATOM   6150 O  O   . LYS B  1 319 ? 5.79713  47.49143  7.87175   1.000 23.51073 ? 350  LYS B O   1 
ATOM   6151 C  CB  . LYS B  1 319 ? 8.17391  49.26254  6.64835   1.000 23.68248 ? 350  LYS B CB  1 
ATOM   6152 C  CG  . LYS B  1 319 ? 6.88445  50.08708  6.61894   1.000 25.20118 ? 350  LYS B CG  1 
ATOM   6153 C  CD  . LYS B  1 319 ? 6.79269  50.97803  5.38472   1.000 30.85560 ? 350  LYS B CD  1 
ATOM   6154 C  CE  . LYS B  1 319 ? 7.16807  52.39082  5.72937   1.000 33.34458 ? 350  LYS B CE  1 
ATOM   6155 N  NZ  . LYS B  1 319 ? 6.96190  53.30026  4.56628   1.000 34.87092 ? 350  LYS B NZ  1 
ATOM   6156 N  N   . LYS B  1 320 ? 7.05502  46.19838  6.51431   1.000 21.31453 ? 351  LYS B N   1 
ATOM   6157 C  CA  . LYS B  1 320 ? 5.92315  45.45568  5.95538   1.000 22.07974 ? 351  LYS B CA  1 
ATOM   6158 C  C   . LYS B  1 320 ? 5.98498  43.95344  6.18968   1.000 22.35924 ? 351  LYS B C   1 
ATOM   6159 O  O   . LYS B  1 320 ? 4.94464  43.32994  6.43619   1.000 22.74944 ? 351  LYS B O   1 
ATOM   6160 C  CB  . LYS B  1 320 ? 5.83421  45.71473  4.44395   1.000 24.56137 ? 351  LYS B CB  1 
ATOM   6161 C  CG  . LYS B  1 320 ? 5.42048  47.12240  4.05811   1.000 28.98468 ? 351  LYS B CG  1 
ATOM   6162 C  CD  . LYS B  1 320 ? 3.95943  47.34907  4.39379   1.000 31.91945 ? 351  LYS B CD  1 
ATOM   6163 C  CE  . LYS B  1 320 ? 3.34056  48.40793  3.49411   1.000 43.38208 ? 351  LYS B CE  1 
ATOM   6164 N  NZ  . LYS B  1 320 ? 1.90570  48.65382  3.84552   1.000 41.52979 ? 351  LYS B NZ  1 
ATOM   6165 N  N   . ILE B  1 321 ? 7.16384  43.34722  6.09786   1.000 20.56161 ? 352  ILE B N   1 
ATOM   6166 C  CA  . ILE B  1 321 ? 7.28084  41.89597  6.16122   1.000 20.59494 ? 352  ILE B CA  1 
ATOM   6167 C  C   . ILE B  1 321 ? 7.55285  41.48598  7.60155   1.000 18.87872 ? 352  ILE B C   1 
ATOM   6168 O  O   . ILE B  1 321 ? 8.53030  41.92774  8.21827   1.000 21.13205 ? 352  ILE B O   1 
ATOM   6169 C  CB  . ILE B  1 321 ? 8.36750  41.38548  5.20599   1.000 20.25051 ? 352  ILE B CB  1 
ATOM   6170 C  CG1 . ILE B  1 321 ? 7.96000  41.71387  3.76640   1.000 20.14902 ? 352  ILE B CG1 1 
ATOM   6171 C  CG2 . ILE B  1 321 ? 8.55835  39.87486  5.38403   1.000 20.31907 ? 352  ILE B CG2 1 
ATOM   6172 C  CD1 . ILE B  1 321 ? 9.03196  41.37137  2.73709   1.000 20.72700 ? 352  ILE B CD1 1 
ATOM   6173 N  N   . LYS B  1 322 ? 6.65229  40.68013  8.15417   1.000 23.42619 ? 353  LYS B N   1 
ATOM   6174 C  CA  . LYS B  1 322 ? 6.76285  40.29051  9.54371   1.000 24.23102 ? 353  LYS B CA  1 
ATOM   6175 C  C   . LYS B  1 322 ? 7.89888  39.29843  9.72800   1.000 25.44060 ? 353  LYS B C   1 
ATOM   6176 O  O   . LYS B  1 322 ? 8.33319  38.62760  8.78783   1.000 23.02536 ? 353  LYS B O   1 
ATOM   6177 C  CB  . LYS B  1 322 ? 5.45563  39.67627  10.02999  1.000 26.00886 ? 353  LYS B CB  1 
ATOM   6178 C  CG  . LYS B  1 322 ? 4.26519  40.56073  9.76238   1.000 34.32491 ? 353  LYS B CG  1 
ATOM   6179 C  CD  . LYS B  1 322 ? 4.44688  41.91535  10.40502  1.000 32.46646 ? 353  LYS B CD  1 
ATOM   6180 C  CE  . LYS B  1 322 ? 3.47045  42.92052  9.80864   1.000 36.19070 ? 353  LYS B CE  1 
ATOM   6181 N  NZ  . LYS B  1 322 ? 3.15864  43.98811  10.78346  1.000 36.01513 ? 353  LYS B NZ  1 
ATOM   6182 N  N   . LYS B  1 323 ? 8.37743  39.21991  10.96550  1.000 22.70961 ? 354  LYS B N   1 
ATOM   6183 C  CA  . LYS B  1 323 ? 9.44185  38.30204  11.32079  1.000 21.92116 ? 354  LYS B CA  1 
ATOM   6184 C  C   . LYS B  1 323 ? 8.95362  36.85486  11.30902  1.000 24.78208 ? 354  LYS B C   1 
ATOM   6185 O  O   . LYS B  1 323 ? 7.75702  36.56363  11.42147  1.000 23.78467 ? 354  LYS B O   1 
ATOM   6186 C  CB  . LYS B  1 323 ? 9.99629  38.64833  12.70330  1.000 25.94112 ? 354  LYS B CB  1 
ATOM   6187 N  N   . ASP B  1 324 ? 9.91773  35.93855  11.16950  1.000 21.73087 ? 355  ASP B N   1 
ATOM   6188 C  CA  . ASP B  1 324 ? 9.70957  34.50161  11.34895  1.000 22.25154 ? 355  ASP B CA  1 
ATOM   6189 C  C   . ASP B  1 324 ? 8.78638  33.90065  10.29661  1.000 23.37451 ? 355  ASP B C   1 
ATOM   6190 O  O   . ASP B  1 324 ? 8.14966  32.87641  10.54824  1.000 26.34291 ? 355  ASP B O   1 
ATOM   6191 C  CB  . ASP B  1 324 ? 9.16455  34.17910  12.74710  1.000 26.55613 ? 355  ASP B CB  1 
ATOM   6192 C  CG  . ASP B  1 324 ? 10.06054 34.68380  13.86089  1.000 37.09132 ? 355  ASP B CG  1 
ATOM   6193 O  OD1 . ASP B  1 324 ? 11.28854 34.46773  13.79198  1.000 39.30551 ? 355  ASP B OD1 1 
ATOM   6194 O  OD2 . ASP B  1 324 ? 9.53027  35.29936  14.81208  1.000 45.04115 ? 355  ASP B OD2 1 
ATOM   6195 N  N   . GLN B  1 325 ? 8.70780  34.50909  9.11743   1.000 22.41118 ? 356  GLN B N   1 
ATOM   6196 C  CA  . GLN B  1 325 ? 7.82730  34.02671  8.06427   1.000 21.39910 ? 356  GLN B CA  1 
ATOM   6197 C  C   . GLN B  1 325 ? 8.54857  32.99488  7.20656   1.000 23.26510 ? 356  GLN B C   1 
ATOM   6198 O  O   . GLN B  1 325 ? 9.74303  33.12636  6.92082   1.000 21.54278 ? 356  GLN B O   1 
ATOM   6199 C  CB  . GLN B  1 325 ? 7.33713  35.17365  7.17418   1.000 23.35072 ? 356  GLN B CB  1 
ATOM   6200 C  CG  . GLN B  1 325 ? 6.31677  34.69811  6.11796   1.000 28.87453 ? 356  GLN B CG  1 
ATOM   6201 C  CD  . GLN B  1 325 ? 5.89593  35.75222  5.08653   1.000 31.07038 ? 356  GLN B CD  1 
ATOM   6202 O  OE1 . GLN B  1 325 ? 5.36136  35.40892  4.02974   1.000 33.38905 ? 356  GLN B OE1 1 
ATOM   6203 N  NE2 . GLN B  1 325 ? 6.12661  37.02532  5.38897   1.000 32.95267 ? 356  GLN B NE2 1 
ATOM   6204 N  N   . ARG B  1 326 ? 7.81415  31.96860  6.79863   1.000 18.87099 ? 357  ARG B N   1 
ATOM   6205 C  CA  . ARG B  1 326 ? 8.28113  31.03402  5.78210   1.000 19.28585 ? 357  ARG B CA  1 
ATOM   6206 C  C   . ARG B  1 326 ? 7.24515  31.00642  4.67390   1.000 20.58846 ? 357  ARG B C   1 
ATOM   6207 O  O   . ARG B  1 326 ? 6.05677  30.77588  4.93193   1.000 22.64807 ? 357  ARG B O   1 
ATOM   6208 C  CB  . ARG B  1 326 ? 8.49657  29.62858  6.34918   1.000 21.78476 ? 357  ARG B CB  1 
ATOM   6209 C  CG  . ARG B  1 326 ? 9.45207  29.60085  7.52546   1.000 24.68094 ? 357  ARG B CG  1 
ATOM   6210 C  CD  . ARG B  1 326 ? 9.59440  28.19084  8.08771   1.000 27.46918 ? 357  ARG B CD  1 
ATOM   6211 N  NE  . ARG B  1 326 ? 10.32441 27.31143  7.18151   1.000 30.70800 ? 357  ARG B NE  1 
ATOM   6212 C  CZ  . ARG B  1 326 ? 11.64828 27.26562  7.10419   1.000 32.53244 ? 357  ARG B CZ  1 
ATOM   6213 N  NH1 . ARG B  1 326 ? 12.41065 28.05458  7.84638   1.000 32.49433 ? 357  ARG B NH1 1 
ATOM   6214 N  NH2 . ARG B  1 326 ? 12.22071 26.40778  6.26446   1.000 32.89608 ? 357  ARG B NH2 1 
ATOM   6215 N  N   . PHE B  1 327 ? 7.68697  31.25379  3.45153   1.000 18.70755 ? 358  PHE B N   1 
ATOM   6216 C  CA  . PHE B  1 327 ? 6.79780  31.28252  2.29776   1.000 16.59322 ? 358  PHE B CA  1 
ATOM   6217 C  C   . PHE B  1 327 ? 7.10478  30.04242  1.47080   1.000 19.13654 ? 358  PHE B C   1 
ATOM   6218 O  O   . PHE B  1 327 ? 8.20588  29.91974  0.91660   1.000 17.76719 ? 358  PHE B O   1 
ATOM   6219 C  CB  . PHE B  1 327 ? 6.99733  32.56062  1.48712   1.000 18.39158 ? 358  PHE B CB  1 
ATOM   6220 C  CG  . PHE B  1 327 ? 5.95932  32.76567  0.42052   1.000 16.56490 ? 358  PHE B CG  1 
ATOM   6221 C  CD1 . PHE B  1 327 ? 4.74574  33.38015  0.72902   1.000 16.88644 ? 358  PHE B CD1 1 
ATOM   6222 C  CD2 . PHE B  1 327 ? 6.19419  32.34863  -0.88441  1.000 18.42717 ? 358  PHE B CD2 1 
ATOM   6223 C  CE1 . PHE B  1 327 ? 3.78050  33.57968  -0.24355  1.000 18.41621 ? 358  PHE B CE1 1 
ATOM   6224 C  CE2 . PHE B  1 327 ? 5.24048  32.54437  -1.86758  1.000 17.28773 ? 358  PHE B CE2 1 
ATOM   6225 C  CZ  . PHE B  1 327 ? 4.02951  33.17019  -1.54891  1.000 17.53340 ? 358  PHE B CZ  1 
ATOM   6226 N  N   . ASP B  1 328 ? 6.14047  29.12624  1.39082   1.000 17.59166 ? 359  ASP B N   1 
ATOM   6227 C  CA  . ASP B  1 328 ? 6.38569  27.80742  0.81805   1.000 16.54641 ? 359  ASP B CA  1 
ATOM   6228 C  C   . ASP B  1 328 ? 5.86757  27.65852  -0.60648  1.000 16.77898 ? 359  ASP B C   1 
ATOM   6229 O  O   . ASP B  1 328 ? 6.14003  26.63071  -1.24274  1.000 19.38304 ? 359  ASP B O   1 
ATOM   6230 C  CB  . ASP B  1 328 ? 5.75271  26.70754  1.69284   1.000 17.53341 ? 359  ASP B CB  1 
ATOM   6231 C  CG  . ASP B  1 328 ? 6.34195  26.65315  3.10899   1.000 22.31140 ? 359  ASP B CG  1 
ATOM   6232 O  OD1 . ASP B  1 328 ? 7.55218  26.89489  3.28393   1.000 20.71171 ? 359  ASP B OD1 1 
ATOM   6233 O  OD2 . ASP B  1 328 ? 5.58095  26.34366  4.05232   1.000 23.84275 ? 359  ASP B OD2 1 
ATOM   6234 N  N   . PHE B  1 329 ? 5.12242  28.62715  -1.11912  1.000 18.65099 ? 360  PHE B N   1 
ATOM   6235 C  CA  . PHE B  1 329 ? 4.67692  28.49224  -2.49849  1.000 18.27916 ? 360  PHE B CA  1 
ATOM   6236 C  C   . PHE B  1 329 ? 5.82093  28.83941  -3.44722  1.000 17.13213 ? 360  PHE B C   1 
ATOM   6237 O  O   . PHE B  1 329 ? 6.64722  29.70709  -3.14174  1.000 18.01206 ? 360  PHE B O   1 
ATOM   6238 C  CB  . PHE B  1 329 ? 3.48417  29.40418  -2.78272  1.000 17.92327 ? 360  PHE B CB  1 
ATOM   6239 C  CG  . PHE B  1 329 ? 2.26055  29.07660  -1.97276  1.000 18.42947 ? 360  PHE B CG  1 
ATOM   6240 C  CD1 . PHE B  1 329 ? 1.61158  27.85680  -2.13524  1.000 21.87866 ? 360  PHE B CD1 1 
ATOM   6241 C  CD2 . PHE B  1 329 ? 1.74942  30.00053  -1.07046  1.000 19.32014 ? 360  PHE B CD2 1 
ATOM   6242 C  CE1 . PHE B  1 329 ? 0.47853  27.55465  -1.40012  1.000 21.85459 ? 360  PHE B CE1 1 
ATOM   6243 C  CE2 . PHE B  1 329 ? 0.61683  29.70309  -0.32705  1.000 21.71027 ? 360  PHE B CE2 1 
ATOM   6244 C  CZ  . PHE B  1 329 ? -0.01872 28.48575  -0.49734  1.000 21.68801 ? 360  PHE B CZ  1 
ATOM   6245 N  N   . PRO B  1 330 ? 5.89037  28.17623  -4.60100  1.000 15.69345 ? 361  PRO B N   1 
ATOM   6246 C  CA  . PRO B  1 330 ? 6.99057  28.45327  -5.53726  1.000 18.77538 ? 361  PRO B CA  1 
ATOM   6247 C  C   . PRO B  1 330 ? 6.94463  29.87715  -6.07865  1.000 17.60928 ? 361  PRO B C   1 
ATOM   6248 O  O   . PRO B  1 330 ? 5.87435  30.43162  -6.36146  1.000 16.76029 ? 361  PRO B O   1 
ATOM   6249 C  CB  . PRO B  1 330 ? 6.79713  27.41803  -6.65123  1.000 22.30485 ? 361  PRO B CB  1 
ATOM   6250 C  CG  . PRO B  1 330 ? 5.44782  26.80842  -6.44100  1.000 21.92520 ? 361  PRO B CG  1 
ATOM   6251 C  CD  . PRO B  1 330 ? 5.06904  27.02063  -5.00021  1.000 19.05207 ? 361  PRO B CD  1 
ATOM   6252 N  N   . VAL B  1 331 ? 8.13820  30.46740  -6.21433  1.000 17.70388 ? 362  VAL B N   1 
ATOM   6253 C  CA  . VAL B  1 331 ? 8.33388  31.80303  -6.76978  1.000 15.86020 ? 362  VAL B CA  1 
ATOM   6254 C  C   . VAL B  1 331 ? 9.55896  31.74712  -7.67179  1.000 15.48784 ? 362  VAL B C   1 
ATOM   6255 O  O   . VAL B  1 331 ? 10.32789 30.77787  -7.65635  1.000 16.19305 ? 362  VAL B O   1 
ATOM   6256 C  CB  . VAL B  1 331 ? 8.53697  32.88805  -5.68556  1.000 17.59770 ? 362  VAL B CB  1 
ATOM   6257 C  CG1 . VAL B  1 331 ? 7.31581  32.98070  -4.76322  1.000 18.71650 ? 362  VAL B CG1 1 
ATOM   6258 C  CG2 . VAL B  1 331 ? 9.80460  32.61103  -4.89405  1.000 17.16762 ? 362  VAL B CG2 1 
ATOM   6259 N  N   . SER B  1 332 ? 9.73758  32.81198  -8.44608  1.000 15.41267 ? 363  SER B N   1 
ATOM   6260 C  CA  . SER B  1 332 ? 10.79212 32.88551  -9.44738  1.000 16.54853 ? 363  SER B CA  1 
ATOM   6261 C  C   . SER B  1 332 ? 11.58763 34.17393  -9.28588  1.000 16.85787 ? 363  SER B C   1 
ATOM   6262 O  O   . SER B  1 332 ? 11.05122 35.21188  -8.89143  1.000 17.39852 ? 363  SER B O   1 
ATOM   6263 C  CB  . SER B  1 332 ? 10.21132 32.82947  -10.87381 1.000 17.44872 ? 363  SER B CB  1 
ATOM   6264 O  OG  . SER B  1 332 ? 11.23981 33.05245  -11.83554 1.000 17.77839 ? 363  SER B OG  1 
ATOM   6265 N  N   . SER B  1 333 ? 12.88552 34.10659  -9.60239  1.000 16.08593 ? 364  SER B N   1 
ATOM   6266 C  CA  . SER B  1 333 ? 13.65340 35.34014  -9.71231  1.000 15.88884 ? 364  SER B CA  1 
ATOM   6267 C  C   . SER B  1 333 ? 13.08189 36.26858  -10.78027 1.000 15.35500 ? 364  SER B C   1 
ATOM   6268 O  O   . SER B  1 333 ? 13.32907 37.47308  -10.72863 1.000 17.16374 ? 364  SER B O   1 
ATOM   6269 C  CB  . SER B  1 333 ? 15.12102 35.03861  -10.02261 1.000 15.49274 ? 364  SER B CB  1 
ATOM   6270 O  OG  . SER B  1 333 ? 15.21610 34.33942  -11.25073 1.000 18.24892 ? 364  SER B OG  1 
ATOM   6271 N  N   . LEU B  1 334 ? 12.32460 35.73356  -11.74405 1.000 16.52823 ? 365  LEU B N   1 
ATOM   6272 C  CA  . LEU B  1 334 ? 11.59040 36.58516  -12.67249 1.000 16.93356 ? 365  LEU B CA  1 
ATOM   6273 C  C   . LEU B  1 334 ? 10.58493 37.48831  -11.96742 1.000 18.06800 ? 365  LEU B C   1 
ATOM   6274 O  O   . LEU B  1 334 ? 10.14205 38.48564  -12.55398 1.000 18.55018 ? 365  LEU B O   1 
ATOM   6275 C  CB  . LEU B  1 334 ? 10.85465 35.72344  -13.69904 1.000 15.76241 ? 365  LEU B CB  1 
ATOM   6276 C  CG  . LEU B  1 334 ? 11.75700 34.89622  -14.61420 1.000 17.96462 ? 365  LEU B CG  1 
ATOM   6277 C  CD1 . LEU B  1 334 ? 10.95878 33.81983  -15.32748 1.000 18.47053 ? 365  LEU B CD1 1 
ATOM   6278 C  CD2 . LEU B  1 334 ? 12.44062 35.81353  -15.61802 1.000 20.27154 ? 365  LEU B CD2 1 
ATOM   6279 N  N   . ASP B  1 335 ? 10.20490 37.16538  -10.72935 1.000 16.59003 ? 366  ASP B N   1 
ATOM   6280 C  CA  . ASP B  1 335 ? 9.25290  38.01496  -10.02286 1.000 16.76313 ? 366  ASP B CA  1 
ATOM   6281 C  C   . ASP B  1 335 ? 9.87587  39.31504  -9.54069  1.000 18.29356 ? 366  ASP B C   1 
ATOM   6282 O  O   . ASP B  1 335 ? 9.14475  40.26104  -9.22446  1.000 17.53583 ? 366  ASP B O   1 
ATOM   6283 C  CB  . ASP B  1 335 ? 8.66064  37.25541  -8.83331  1.000 17.49725 ? 366  ASP B CB  1 
ATOM   6284 C  CG  . ASP B  1 335 ? 7.93372  35.99483  -9.25543  1.000 19.71067 ? 366  ASP B CG  1 
ATOM   6285 O  OD1 . ASP B  1 335 ? 7.41618  35.94086  -10.39832 1.000 18.80374 ? 366  ASP B OD1 1 
ATOM   6286 O  OD2 . ASP B  1 335 ? 7.87818  35.05173  -8.44478  1.000 18.01364 ? 366  ASP B OD2 1 
ATOM   6287 N  N   . LEU B  1 336 ? 11.20519 39.40067  -9.48781  1.000 18.71648 ? 367  LEU B N   1 
ATOM   6288 C  CA  . LEU B  1 336 ? 11.81236 40.59179  -8.90924  1.000 16.92071 ? 367  LEU B CA  1 
ATOM   6289 C  C   . LEU B  1 336 ? 11.50982 41.82958  -9.74614  1.000 16.29557 ? 367  LEU B C   1 
ATOM   6290 O  O   . LEU B  1 336 ? 11.18820 42.88402  -9.19751  1.000 18.03756 ? 367  LEU B O   1 
ATOM   6291 C  CB  . LEU B  1 336 ? 13.31675 40.38990  -8.74577  1.000 16.40665 ? 367  LEU B CB  1 
ATOM   6292 C  CG  . LEU B  1 336 ? 13.71382 39.22118  -7.83222  1.000 18.58609 ? 367  LEU B CG  1 
ATOM   6293 C  CD1 . LEU B  1 336 ? 15.22386 39.21054  -7.64021  1.000 19.32846 ? 367  LEU B CD1 1 
ATOM   6294 C  CD2 . LEU B  1 336 ? 12.99464 39.26818  -6.47394  1.000 18.25429 ? 367  LEU B CD2 1 
ATOM   6295 N  N   . TYR B  1 337 ? 11.56495 41.71176  -11.07454 1.000 17.48691 ? 368  TYR B N   1 
ATOM   6296 C  CA  . TYR B  1 337 ? 11.31941 42.87433  -11.93083 1.000 18.35801 ? 368  TYR B CA  1 
ATOM   6297 C  C   . TYR B  1 337 ? 9.93884  43.48453  -11.68315 1.000 19.67299 ? 368  TYR B C   1 
ATOM   6298 O  O   . TYR B  1 337 ? 9.86738  44.65635  -11.26807 1.000 19.30907 ? 368  TYR B O   1 
ATOM   6299 C  CB  . TYR B  1 337 ? 11.56133 42.45957  -13.39070 1.000 17.23006 ? 368  TYR B CB  1 
ATOM   6300 C  CG  . TYR B  1 337 ? 11.69256 43.55912  -14.43999 1.000 18.86741 ? 368  TYR B CG  1 
ATOM   6301 C  CD1 . TYR B  1 337 ? 10.77484 44.60116  -14.52923 1.000 18.93860 ? 368  TYR B CD1 1 
ATOM   6302 C  CD2 . TYR B  1 337 ? 12.71691 43.50696  -15.37740 1.000 18.58397 ? 368  TYR B CD2 1 
ATOM   6303 C  CE1 . TYR B  1 337 ? 10.89914 45.59029  -15.50975 1.000 19.67578 ? 368  TYR B CE1 1 
ATOM   6304 C  CE2 . TYR B  1 337 ? 12.84228 44.47385  -16.36177 1.000 19.78327 ? 368  TYR B CE2 1 
ATOM   6305 C  CZ  . TYR B  1 337 ? 11.93342 45.50932  -16.42111 1.000 20.87488 ? 368  TYR B CZ  1 
ATOM   6306 O  OH  . TYR B  1 337 ? 12.07520 46.46311  -17.40103 1.000 21.98650 ? 368  TYR B OH  1 
ATOM   6307 N  N   . PRO B  1 338 ? 8.82195  42.77040  -11.88457 1.000 19.82544 ? 369  PRO B N   1 
ATOM   6308 C  CA  . PRO B  1 338 ? 7.51430  43.40259  -11.62109 1.000 18.92805 ? 369  PRO B CA  1 
ATOM   6309 C  C   . PRO B  1 338 ? 7.27439  43.73564  -10.15496 1.000 19.99375 ? 369  PRO B C   1 
ATOM   6310 O  O   . PRO B  1 338 ? 6.56363  44.71032  -9.86058  1.000 20.39914 ? 369  PRO B O   1 
ATOM   6311 C  CB  . PRO B  1 338 ? 6.51037  42.36010  -12.13985 1.000 19.67235 ? 369  PRO B CB  1 
ATOM   6312 C  CG  . PRO B  1 338 ? 7.24848  41.04513  -12.07617 1.000 18.76586 ? 369  PRO B CG  1 
ATOM   6313 C  CD  . PRO B  1 338 ? 8.66513  41.40019  -12.41755 1.000 18.00529 ? 369  PRO B CD  1 
ATOM   6314 N  N   . THR B  1 339 ? 7.83051  42.96640  -9.21901  1.000 18.30486 ? 370  THR B N   1 
ATOM   6315 C  CA  . THR B  1 339 ? 7.66683  43.31909  -7.81120  1.000 17.51594 ? 370  THR B CA  1 
ATOM   6316 C  C   . THR B  1 339 ? 8.35222  44.64191  -7.49968  1.000 19.16570 ? 370  THR B C   1 
ATOM   6317 O  O   . THR B  1 339 ? 7.77920  45.51336  -6.83243  1.000 19.85318 ? 370  THR B O   1 
ATOM   6318 C  CB  . THR B  1 339 ? 8.22567  42.20667  -6.91979  1.000 17.41050 ? 370  THR B CB  1 
ATOM   6319 O  OG1 . THR B  1 339 ? 7.52145  40.98761  -7.18734  1.000 18.02758 ? 370  THR B OG1 1 
ATOM   6320 C  CG2 . THR B  1 339 ? 8.07128  42.55945  -5.44504  1.000 20.78050 ? 370  THR B CG2 1 
ATOM   6321 N  N   . PHE B  1 340 ? 9.59525  44.79914  -7.96237  1.000 18.90853 ? 371  PHE B N   1 
ATOM   6322 C  CA  . PHE B  1 340 ? 10.34580 46.02173  -7.69690  1.000 17.97800 ? 371  PHE B CA  1 
ATOM   6323 C  C   . PHE B  1 340 ? 9.73382  47.22081  -8.41448  1.000 17.72817 ? 371  PHE B C   1 
ATOM   6324 O  O   . PHE B  1 340 ? 9.65626  48.31617  -7.84256  1.000 19.63753 ? 371  PHE B O   1 
ATOM   6325 C  CB  . PHE B  1 340 ? 11.80343 45.87295  -8.12700  1.000 18.67116 ? 371  PHE B CB  1 
ATOM   6326 C  CG  . PHE B  1 340 ? 12.60256 44.90314  -7.30949  1.000 18.57484 ? 371  PHE B CG  1 
ATOM   6327 C  CD1 . PHE B  1 340 ? 12.09762 44.34244  -6.13970  1.000 17.85851 ? 371  PHE B CD1 1 
ATOM   6328 C  CD2 . PHE B  1 340 ? 13.87886 44.54359  -7.72680  1.000 17.71300 ? 371  PHE B CD2 1 
ATOM   6329 C  CE1 . PHE B  1 340 ? 12.85295 43.42662  -5.40269  1.000 18.75058 ? 371  PHE B CE1 1 
ATOM   6330 C  CE2 . PHE B  1 340 ? 14.64205 43.64319  -7.00191  1.000 16.92296 ? 371  PHE B CE2 1 
ATOM   6331 C  CZ  . PHE B  1 340 ? 14.12988 43.07805  -5.83434  1.000 18.78520 ? 371  PHE B CZ  1 
ATOM   6332 N  N   . THR B  1 341 ? 9.34133  47.05717  -9.68343  1.000 19.30316 ? 372  THR B N   1 
ATOM   6333 C  CA  . THR B  1 341 ? 8.73960  48.19642  -10.36929 1.000 20.42843 ? 372  THR B CA  1 
ATOM   6334 C  C   . THR B  1 341 ? 7.38740  48.54627  -9.75750  1.000 22.22903 ? 372  THR B C   1 
ATOM   6335 O  O   . THR B  1 341 ? 7.01081  49.72465  -9.72816  1.000 21.87586 ? 372  THR B O   1 
ATOM   6336 C  CB  . THR B  1 341 ? 8.61512  47.94314  -11.87525 1.000 23.31322 ? 372  THR B CB  1 
ATOM   6337 O  OG1 . THR B  1 341 ? 7.79528  46.80104  -12.12570 1.000 24.46152 ? 372  THR B OG1 1 
ATOM   6338 C  CG2 . THR B  1 341 ? 9.97794  47.72642  -12.50438 1.000 25.09259 ? 372  THR B CG2 1 
ATOM   6339 N  N   . GLY B  1 342 ? 6.67934  47.55646  -9.20984  1.000 20.75797 ? 373  GLY B N   1 
ATOM   6340 C  CA  . GLY B  1 342 ? 5.46194  47.85349  -8.46805  1.000 22.68102 ? 373  GLY B CA  1 
ATOM   6341 C  C   . GLY B  1 342 ? 5.72637  48.69880  -7.23492  1.000 21.86004 ? 373  GLY B C   1 
ATOM   6342 O  O   . GLY B  1 342 ? 5.05301  49.70661  -7.00043  1.000 22.81076 ? 373  GLY B O   1 
ATOM   6343 N  N   . LEU B  1 343 ? 6.70901  48.29168  -6.42059  1.000 19.17847 ? 374  LEU B N   1 
ATOM   6344 C  CA  . LEU B  1 343 ? 7.06775  49.06678  -5.23651  1.000 20.48888 ? 374  LEU B CA  1 
ATOM   6345 C  C   . LEU B  1 343 ? 7.53849  50.46899  -5.58669  1.000 20.32849 ? 374  LEU B C   1 
ATOM   6346 O  O   . LEU B  1 343 ? 7.30562  51.40942  -4.81791  1.000 23.11305 ? 374  LEU B O   1 
ATOM   6347 C  CB  . LEU B  1 343 ? 8.16097  48.35158  -4.44898  1.000 21.87238 ? 374  LEU B CB  1 
ATOM   6348 C  CG  . LEU B  1 343 ? 7.75736  47.00197  -3.87296  1.000 22.26887 ? 374  LEU B CG  1 
ATOM   6349 C  CD1 . LEU B  1 343 ? 8.98099  46.34707  -3.27030  1.000 25.08077 ? 374  LEU B CD1 1 
ATOM   6350 C  CD2 . LEU B  1 343 ? 6.67253  47.19217  -2.82866  1.000 27.59241 ? 374  LEU B CD2 1 
ATOM   6351 N  N   . ALA B  1 344 ? 8.21498  50.62942  -6.71843  1.000 21.16037 ? 375  ALA B N   1 
ATOM   6352 C  CA  . ALA B  1 344 ? 8.70664  51.93606  -7.12613  1.000 19.44873 ? 375  ALA B CA  1 
ATOM   6353 C  C   . ALA B  1 344 ? 7.65069  52.77438  -7.82131  1.000 21.95243 ? 375  ALA B C   1 
ATOM   6354 O  O   . ALA B  1 344 ? 7.95985  53.89805  -8.24108  1.000 22.44253 ? 375  ALA B O   1 
ATOM   6355 C  CB  . ALA B  1 344 ? 9.89830  51.77971  -8.06236  1.000 21.73540 ? 375  ALA B CB  1 
ATOM   6356 N  N   . GLU B  1 345 ? 6.43841  52.24329  -7.98044  1.000 22.51783 ? 376  GLU B N   1 
ATOM   6357 C  CA  . GLU B  1 345 ? 5.37228  52.93135  -8.70796  1.000 24.21564 ? 376  GLU B CA  1 
ATOM   6358 C  C   . GLU B  1 345 ? 5.86279  53.38277  -10.08127 1.000 29.21739 ? 376  GLU B C   1 
ATOM   6359 O  O   . GLU B  1 345 ? 5.55847  54.48305  -10.55102 1.000 28.24545 ? 376  GLU B O   1 
ATOM   6360 C  CB  . GLU B  1 345 ? 4.83140  54.11219  -7.90171  1.000 23.54698 ? 376  GLU B CB  1 
ATOM   6361 C  CG  . GLU B  1 345 ? 4.33666  53.74815  -6.51155  1.000 26.74472 ? 376  GLU B CG  1 
ATOM   6362 C  CD  . GLU B  1 345 ? 3.78708  54.95837  -5.75847  1.000 33.87488 ? 376  GLU B CD  1 
ATOM   6363 O  OE1 . GLU B  1 345 ? 4.54043  55.93039  -5.53853  1.000 31.95547 ? 376  GLU B OE1 1 
ATOM   6364 O  OE2 . GLU B  1 345 ? 2.58707  54.94626  -5.41091  1.000 39.11833 ? 376  GLU B OE2 1 
ATOM   6365 N  N   . ALA B  1 346 ? 6.65275  52.53057  -10.72311 1.000 23.59735 ? 377  ALA B N   1 
ATOM   6366 C  CA  . ALA B  1 346 ? 7.32551  52.88039  -11.96324 1.000 26.45077 ? 377  ALA B CA  1 
ATOM   6367 C  C   . ALA B  1 346 ? 6.52106  52.36632  -13.14551 1.000 35.66320 ? 377  ALA B C   1 
ATOM   6368 O  O   . ALA B  1 346 ? 6.03217  51.23315  -13.13091 1.000 37.95676 ? 377  ALA B O   1 
ATOM   6369 C  CB  . ALA B  1 346 ? 8.73710  52.29569  -11.99720 1.000 27.10892 ? 377  ALA B CB  1 
ATOM   6370 N  N   . LYS B  1 347 ? 6.37707  53.20668  -14.16385 1.000 30.15682 ? 378  LYS B N   1 
ATOM   6371 C  CA  . LYS B  1 347 ? 5.70537  52.78915  -15.38268 1.000 32.24849 ? 378  LYS B CA  1 
ATOM   6372 C  C   . LYS B  1 347 ? 6.65814  51.97754  -16.24997 1.000 29.81278 ? 378  LYS B C   1 
ATOM   6373 O  O   . LYS B  1 347 ? 7.83901  52.31272  -16.38211 1.000 32.49623 ? 378  LYS B O   1 
ATOM   6374 C  CB  . LYS B  1 347 ? 5.19420  54.00686  -16.15646 1.000 38.04035 ? 378  LYS B CB  1 
ATOM   6375 N  N   . LEU B  1 348 ? 6.13863  50.90199  -16.83557 1.000 28.32582 ? 379  LEU B N   1 
ATOM   6376 C  CA  . LEU B  1 348 ? 6.93452  50.08158  -17.73114 1.000 30.06922 ? 379  LEU B CA  1 
ATOM   6377 C  C   . LEU B  1 348 ? 7.02126  50.72629  -19.10989 1.000 32.97550 ? 379  LEU B C   1 
ATOM   6378 O  O   . LEU B  1 348 ? 6.08911  51.41025  -19.53850 1.000 31.44009 ? 379  LEU B O   1 
ATOM   6379 C  CB  . LEU B  1 348 ? 6.32701  48.69039  -17.86256 1.000 29.94325 ? 379  LEU B CB  1 
ATOM   6380 C  CG  . LEU B  1 348 ? 6.33602  47.79583  -16.62936 1.000 34.94659 ? 379  LEU B CG  1 
ATOM   6381 C  CD1 . LEU B  1 348 ? 5.72132  46.44633  -16.97758 1.000 33.26919 ? 379  LEU B CD1 1 
ATOM   6382 C  CD2 . LEU B  1 348 ? 7.76487  47.63633  -16.13161 1.000 30.39514 ? 379  LEU B CD2 1 
ATOM   6383 N  N   . PRO B  1 349 ? 8.12695  50.51390  -19.82526 1.000 29.03716 ? 380  PRO B N   1 
ATOM   6384 C  CA  . PRO B  1 349 ? 8.21805  51.01293  -21.20188 1.000 31.83866 ? 380  PRO B CA  1 
ATOM   6385 C  C   . PRO B  1 349 ? 7.14891  50.37304  -22.07204 1.000 30.96576 ? 380  PRO B C   1 
ATOM   6386 O  O   . PRO B  1 349 ? 6.69515  49.25524  -21.81564 1.000 29.23406 ? 380  PRO B O   1 
ATOM   6387 C  CB  . PRO B  1 349 ? 9.62519  50.59225  -21.64621 1.000 35.75100 ? 380  PRO B CB  1 
ATOM   6388 C  CG  . PRO B  1 349 ? 10.36548 50.27511  -20.37614 1.000 33.92243 ? 380  PRO B CG  1 
ATOM   6389 C  CD  . PRO B  1 349 ? 9.33932  49.78356  -19.41456 1.000 30.35487 ? 380  PRO B CD  1 
ATOM   6390 N  N   . LYS B  1 350 ? 6.73730  51.10141  -23.10656 1.000 32.80825 ? 381  LYS B N   1 
ATOM   6391 C  CA  . LYS B  1 350 ? 5.72524  50.58153  -24.01526 1.000 36.05911 ? 381  LYS B CA  1 
ATOM   6392 C  C   . LYS B  1 350 ? 6.22211  49.30280  -24.67682 1.000 29.03418 ? 381  LYS B C   1 
ATOM   6393 O  O   . LYS B  1 350 ? 7.33868  49.25190  -25.20090 1.000 35.18220 ? 381  LYS B O   1 
ATOM   6394 C  CB  . LYS B  1 350 ? 5.37546  51.62645  -25.07608 1.000 35.84811 ? 381  LYS B CB  1 
ATOM   6395 N  N   . GLY B  1 351 ? 5.39718  48.25981  -24.62871 1.000 31.79730 ? 382  GLY B N   1 
ATOM   6396 C  CA  . GLY B  1 351 ? 5.72800  46.99747  -25.25427 1.000 33.42088 ? 382  GLY B CA  1 
ATOM   6397 C  C   . GLY B  1 351 ? 6.58590  46.06573  -24.42599 1.000 30.78882 ? 382  GLY B C   1 
ATOM   6398 O  O   . GLY B  1 351 ? 6.86699  44.95063  -24.88026 1.000 29.10064 ? 382  GLY B O   1 
ATOM   6399 N  N   . LYS B  1 352 ? 7.00938  46.47805  -23.23249 1.000 26.24777 ? 383  LYS B N   1 
ATOM   6400 C  CA  . LYS B  1 352 ? 7.84037  45.61389  -22.40213 1.000 25.54154 ? 383  LYS B CA  1 
ATOM   6401 C  C   . LYS B  1 352 ? 7.05822  44.37828  -21.98227 1.000 25.77368 ? 383  LYS B C   1 
ATOM   6402 O  O   . LYS B  1 352 ? 5.91507  44.47794  -21.53112 1.000 27.13066 ? 383  LYS B O   1 
ATOM   6403 C  CB  . LYS B  1 352 ? 8.32940  46.37833  -21.17065 1.000 26.61468 ? 383  LYS B CB  1 
ATOM   6404 C  CG  . LYS B  1 352 ? 9.11289  45.52886  -20.16361 1.000 25.54630 ? 383  LYS B CG  1 
ATOM   6405 C  CD  . LYS B  1 352 ? 10.47205 45.10070  -20.70908 1.000 22.32439 ? 383  LYS B CD  1 
ATOM   6406 C  CE  . LYS B  1 352 ? 11.14598 44.12834  -19.73009 1.000 22.09340 ? 383  LYS B CE  1 
ATOM   6407 N  NZ  . LYS B  1 352 ? 12.52871 43.73945  -20.12569 1.000 22.67237 ? 383  LYS B NZ  1 
ATOM   6408 N  N   . GLN B  1 353 ? 7.67591  43.20898  -22.14467 1.000 23.17280 ? 384  GLN B N   1 
ATOM   6409 C  CA  A GLN B  1 353 ? 7.08906  41.92985  -21.77121 0.524 24.42802 ? 384  GLN B CA  1 
ATOM   6410 C  CA  B GLN B  1 353 ? 7.07432  41.94391  -21.75555 0.476 24.43266 ? 384  GLN B CA  1 
ATOM   6411 C  C   . GLN B  1 353 ? 7.81783  41.38364  -20.55165 1.000 23.82063 ? 384  GLN B C   1 
ATOM   6412 O  O   . GLN B  1 353 ? 9.03668  41.53991  -20.43552 1.000 23.04572 ? 384  GLN B O   1 
ATOM   6413 C  CB  A GLN B  1 353 ? 7.18705  40.92188  -22.91943 0.524 27.56901 ? 384  GLN B CB  1 
ATOM   6414 C  CB  B GLN B  1 353 ? 7.09870  40.93948  -22.91108 0.476 27.59575 ? 384  GLN B CB  1 
ATOM   6415 C  CG  A GLN B  1 353 ? 6.52330  41.37333  -24.21001 0.524 31.02820 ? 384  GLN B CG  1 
ATOM   6416 C  CG  B GLN B  1 353 ? 6.18130  41.32132  -24.07010 0.476 30.84874 ? 384  GLN B CG  1 
ATOM   6417 C  CD  A GLN B  1 353 ? 5.01469  41.38635  -24.11023 0.524 31.93352 ? 384  GLN B CD  1 
ATOM   6418 C  CD  B GLN B  1 353 ? 6.34828  40.42143  -25.28026 0.476 29.79208 ? 384  GLN B CD  1 
ATOM   6419 O  OE1 A GLN B  1 353 ? 4.38289  40.34170  -23.95994 0.524 33.66824 ? 384  GLN B OE1 1 
ATOM   6420 O  OE1 B GLN B  1 353 ? 7.02355  39.39688  -25.22011 0.476 37.17528 ? 384  GLN B OE1 1 
ATOM   6421 N  NE2 A GLN B  1 353 ? 4.42709  42.57355  -24.18977 0.524 35.63578 ? 384  GLN B NE2 1 
ATOM   6422 N  NE2 B GLN B  1 353 ? 5.73479  40.80772  -26.39081 0.476 36.49757 ? 384  GLN B NE2 1 
ATOM   6423 N  N   . LEU B  1 354 ? 7.06758  40.74516  -19.65232 1.000 22.70759 ? 385  LEU B N   1 
ATOM   6424 C  CA  . LEU B  1 354 ? 7.60637  40.20113  -18.41205 1.000 20.55524 ? 385  LEU B CA  1 
ATOM   6425 C  C   . LEU B  1 354 ? 7.04569  38.80625  -18.18531 1.000 21.47838 ? 385  LEU B C   1 
ATOM   6426 O  O   . LEU B  1 354 ? 5.85665  38.55857  -18.41285 1.000 24.27135 ? 385  LEU B O   1 
ATOM   6427 C  CB  . LEU B  1 354 ? 7.26221  41.08910  -17.20800 1.000 20.48896 ? 385  LEU B CB  1 
ATOM   6428 C  CG  . LEU B  1 354 ? 7.91526  42.47000  -17.10926 1.000 22.51070 ? 385  LEU B CG  1 
ATOM   6429 C  CD1 . LEU B  1 354 ? 7.38236  43.24951  -15.89822 1.000 24.05051 ? 385  LEU B CD1 1 
ATOM   6430 C  CD2 . LEU B  1 354 ? 9.43322  42.35115  -17.03860 1.000 21.37593 ? 385  LEU B CD2 1 
ATOM   6431 N  N   . ASP B  1 355 ? 7.90477  37.89631  -17.72960 1.000 19.86341 ? 386  ASP B N   1 
ATOM   6432 C  CA  . ASP B  1 355 ? 7.49217  36.52215  -17.50540 1.000 18.56171 ? 386  ASP B CA  1 
ATOM   6433 C  C   . ASP B  1 355 ? 7.15980  36.22081  -16.05022 1.000 21.43598 ? 386  ASP B C   1 
ATOM   6434 O  O   . ASP B  1 355 ? 6.62028  35.14634  -15.77034 1.000 22.92577 ? 386  ASP B O   1 
ATOM   6435 C  CB  . ASP B  1 355 ? 8.58794  35.56087  -17.98669 1.000 20.00941 ? 386  ASP B CB  1 
ATOM   6436 C  CG  . ASP B  1 355 ? 8.68319  35.50497  -19.49483 1.000 24.67335 ? 386  ASP B CG  1 
ATOM   6437 O  OD1 . ASP B  1 355 ? 7.62200  35.52119  -20.15391 1.000 28.86408 ? 386  ASP B OD1 1 
ATOM   6438 O  OD2 . ASP B  1 355 ? 9.80698  35.44117  -20.02498 1.000 23.50876 ? 386  ASP B OD2 1 
ATOM   6439 N  N   . GLY B  1 356 ? 7.48065  37.12524  -15.12567 1.000 20.14720 ? 387  GLY B N   1 
ATOM   6440 C  CA  . GLY B  1 356 ? 7.22439  36.92215  -13.71662 1.000 19.39149 ? 387  GLY B CA  1 
ATOM   6441 C  C   . GLY B  1 356 ? 6.02407  37.71644  -13.23171 1.000 20.32209 ? 387  GLY B C   1 
ATOM   6442 O  O   . GLY B  1 356 ? 5.26675  38.30070  -14.01003 1.000 21.09752 ? 387  GLY B O   1 
ATOM   6443 N  N   . LYS B  1 357 ? 5.85728  37.73235  -11.90637 1.000 18.98049 ? 388  LYS B N   1 
ATOM   6444 C  CA  . LYS B  1 357 ? 4.68716  38.31232  -11.25881 1.000 19.44588 ? 388  LYS B CA  1 
ATOM   6445 C  C   . LYS B  1 357 ? 5.10034  39.26183  -10.14622 1.000 19.05122 ? 388  LYS B C   1 
ATOM   6446 O  O   . LYS B  1 357 ? 6.14117  39.08035  -9.50608  1.000 20.42795 ? 388  LYS B O   1 
ATOM   6447 C  CB  . LYS B  1 357 ? 3.78777  37.22813  -10.65670 1.000 20.69034 ? 388  LYS B CB  1 
ATOM   6448 C  CG  . LYS B  1 357 ? 3.31336  36.17712  -11.64633 1.000 23.29863 ? 388  LYS B CG  1 
ATOM   6449 C  CD  . LYS B  1 357 ? 2.42716  35.14492  -10.95511 1.000 23.87110 ? 388  LYS B CD  1 
ATOM   6450 C  CE  . LYS B  1 357 ? 1.95164  34.06976  -11.92763 1.000 24.78901 ? 388  LYS B CE  1 
ATOM   6451 N  NZ  . LYS B  1 357 ? 1.01013  34.63694  -12.95282 1.000 28.38482 ? 388  LYS B NZ  1 
ATOM   6452 N  N   . ASN B  1 358 ? 4.25226  40.26215  -9.89676  1.000 19.50717 ? 389  ASN B N   1 
ATOM   6453 C  CA  . ASN B  1 358 ? 4.39135  41.10138  -8.71144  1.000 19.85595 ? 389  ASN B CA  1 
ATOM   6454 C  C   . ASN B  1 358 ? 3.84906  40.31823  -7.52424  1.000 20.11001 ? 389  ASN B C   1 
ATOM   6455 O  O   . ASN B  1 358 ? 2.62895  40.17920  -7.37219  1.000 22.16788 ? 389  ASN B O   1 
ATOM   6456 C  CB  . ASN B  1 358 ? 3.63895  42.41689  -8.89807  1.000 21.56683 ? 389  ASN B CB  1 
ATOM   6457 C  CG  . ASN B  1 358 ? 3.76409  43.35253  -7.70448  1.000 21.60267 ? 389  ASN B CG  1 
ATOM   6458 O  OD1 . ASN B  1 358 ? 4.22702  42.97290  -6.63151  1.000 21.05542 ? 389  ASN B OD1 1 
ATOM   6459 N  ND2 . ASN B  1 358 ? 3.32400  44.59702  -7.89119  1.000 24.44161 ? 389  ASN B ND2 1 
ATOM   6460 N  N   . ILE B  1 359 ? 4.74018  39.80227  -6.67456  1.000 16.74602 ? 390  ILE B N   1 
ATOM   6461 C  CA  . ILE B  1 359 ? 4.33650  38.83418  -5.66196  1.000 17.03841 ? 390  ILE B CA  1 
ATOM   6462 C  C   . ILE B  1 359 ? 4.24707  39.43515  -4.26116  1.000 18.93102 ? 390  ILE B C   1 
ATOM   6463 O  O   . ILE B  1 359 ? 4.00212  38.69183  -3.30762  1.000 19.39622 ? 390  ILE B O   1 
ATOM   6464 C  CB  . ILE B  1 359 ? 5.26670  37.60306  -5.63701  1.000 17.33185 ? 390  ILE B CB  1 
ATOM   6465 C  CG1 . ILE B  1 359 ? 6.69589  37.99946  -5.27204  1.000 19.21330 ? 390  ILE B CG1 1 
ATOM   6466 C  CG2 . ILE B  1 359 ? 5.21434  36.85403  -6.95446  1.000 17.66384 ? 390  ILE B CG2 1 
ATOM   6467 C  CD1 . ILE B  1 359 ? 7.57479  36.80010  -4.91351  1.000 18.71608 ? 390  ILE B CD1 1 
ATOM   6468 N  N   . MET B  1 360 ? 4.43080  40.75099  -4.09807  1.000 20.28062 ? 391  MET B N   1 
ATOM   6469 C  CA  . MET B  1 360 ? 4.51961  41.26789  -2.73193  1.000 18.26158 ? 391  MET B CA  1 
ATOM   6470 C  C   . MET B  1 360 ? 3.22030  41.04514  -1.95872  1.000 20.59268 ? 391  MET B C   1 
ATOM   6471 O  O   . MET B  1 360 ? 3.25695  40.64218  -0.79227  1.000 20.62426 ? 391  MET B O   1 
ATOM   6472 C  CB  . MET B  1 360 ? 4.90090  42.74550  -2.71502  1.000 19.98676 ? 391  MET B CB  1 
ATOM   6473 C  CG  . MET B  1 360 ? 5.18873  43.25088  -1.28841  1.000 21.16922 ? 391  MET B CG  1 
ATOM   6474 S  SD  . MET B  1 360 ? 6.50876  42.35521  -0.42255  1.000 23.18737 ? 391  MET B SD  1 
ATOM   6475 C  CE  . MET B  1 360 ? 7.93982  42.96416  -1.30359  1.000 21.98682 ? 391  MET B CE  1 
ATOM   6476 N  N   . ASP B  1 361 ? 2.06298  41.30765  -2.57900  1.000 19.74554 ? 392  ASP B N   1 
ATOM   6477 C  CA  . ASP B  1 361 ? 0.81081  41.05715  -1.86552  1.000 21.82600 ? 392  ASP B CA  1 
ATOM   6478 C  C   . ASP B  1 361 ? 0.64206  39.56901  -1.55759  1.000 21.78386 ? 392  ASP B C   1 
ATOM   6479 O  O   . ASP B  1 361 ? 0.13258  39.20444  -0.49248  1.000 20.55291 ? 392  ASP B O   1 
ATOM   6480 C  CB  . ASP B  1 361 ? -0.39029 41.58252  -2.65945  1.000 23.71646 ? 392  ASP B CB  1 
ATOM   6481 C  CG  . ASP B  1 361 ? -0.63936 43.08011  -2.44000  1.000 34.80063 ? 392  ASP B CG  1 
ATOM   6482 O  OD1 . ASP B  1 361 ? -0.03025 43.67692  -1.52396  1.000 32.70764 ? 392  ASP B OD1 1 
ATOM   6483 O  OD2 . ASP B  1 361 ? -1.45401 43.66242  -3.18781  1.000 34.93557 ? 392  ASP B OD2 1 
ATOM   6484 N  N   . ASP B  1 362 ? 1.08004  38.68886  -2.46568  1.000 21.07867 ? 393  ASP B N   1 
ATOM   6485 C  CA  . ASP B  1 362 ? 1.02345  37.25816  -2.17296  1.000 21.28403 ? 393  ASP B CA  1 
ATOM   6486 C  C   . ASP B  1 362 ? 1.87612  36.91498  -0.96226  1.000 19.92473 ? 393  ASP B C   1 
ATOM   6487 O  O   . ASP B  1 362 ? 1.49088  36.08027  -0.13753  1.000 19.39667 ? 393  ASP B O   1 
ATOM   6488 C  CB  . ASP B  1 362 ? 1.49826  36.43979  -3.37393  1.000 21.23520 ? 393  ASP B CB  1 
ATOM   6489 C  CG  . ASP B  1 362 ? 0.53134  36.47892  -4.53663  1.000 25.12260 ? 393  ASP B CG  1 
ATOM   6490 O  OD1 . ASP B  1 362 ? -0.56669 35.89291  -4.42374  1.000 26.84534 ? 393  ASP B OD1 1 
ATOM   6491 O  OD2 . ASP B  1 362 ? 0.88104  37.09362  -5.56580  1.000 26.79792 ? 393  ASP B OD2 1 
ATOM   6492 N  N   . VAL B  1 363 ? 3.05476  37.53759  -0.85345  1.000 19.23837 ? 394  VAL B N   1 
ATOM   6493 C  CA  . VAL B  1 363 ? 3.94699  37.25737  0.26550   1.000 20.18742 ? 394  VAL B CA  1 
ATOM   6494 C  C   . VAL B  1 363 ? 3.31500  37.71140  1.57694   1.000 22.74421 ? 394  VAL B C   1 
ATOM   6495 O  O   . VAL B  1 363 ? 3.31754  36.97765  2.57464   1.000 21.11707 ? 394  VAL B O   1 
ATOM   6496 C  CB  . VAL B  1 363 ? 5.31663  37.91781  0.02842   1.000 20.97824 ? 394  VAL B CB  1 
ATOM   6497 C  CG1 . VAL B  1 363 ? 6.18701  37.82979  1.27176   1.000 22.28341 ? 394  VAL B CG1 1 
ATOM   6498 C  CG2 . VAL B  1 363 ? 6.01492  37.24248  -1.15391  1.000 20.01751 ? 394  VAL B CG2 1 
ATOM   6499 N  N   . LEU B  1 364 ? 2.74622  38.91527  1.58996   1.000 20.08895 ? 395  LEU B N   1 
ATOM   6500 C  CA  . LEU B  1 364 ? 2.14921  39.42126  2.82428   1.000 19.60934 ? 395  LEU B CA  1 
ATOM   6501 C  C   . LEU B  1 364 ? 0.90682  38.61977  3.21640   1.000 21.86642 ? 395  LEU B C   1 
ATOM   6502 O  O   . LEU B  1 364 ? 0.64006  38.41980  4.40814   1.000 22.05547 ? 395  LEU B O   1 
ATOM   6503 C  CB  . LEU B  1 364 ? 1.80943  40.90342  2.66039   1.000 20.62348 ? 395  LEU B CB  1 
ATOM   6504 C  CG  . LEU B  1 364 ? 3.00364  41.81778  2.38611   1.000 22.42238 ? 395  LEU B CG  1 
ATOM   6505 C  CD1 . LEU B  1 364 ? 2.52403  43.22085  2.03221   1.000 26.39997 ? 395  LEU B CD1 1 
ATOM   6506 C  CD2 . LEU B  1 364 ? 3.95143  41.84597  3.58900   1.000 24.03608 ? 395  LEU B CD2 1 
ATOM   6507 N  N   . LYS B  1 365 ? 0.13027  38.16672  2.23715   1.000 18.76454 ? 396  LYS B N   1 
ATOM   6508 C  CA  . LYS B  1 365 ? -1.12656 37.46975  2.50477   1.000 21.26394 ? 396  LYS B CA  1 
ATOM   6509 C  C   . LYS B  1 365 ? -0.97420 35.95391  2.55542   1.000 20.77472 ? 396  LYS B C   1 
ATOM   6510 O  O   . LYS B  1 365 ? -1.95590 35.25289  2.84525   1.000 19.24403 ? 396  LYS B O   1 
ATOM   6511 C  CB  . LYS B  1 365 ? -2.16991 37.84160  1.44572   1.000 20.14502 ? 396  LYS B CB  1 
ATOM   6512 C  CG  . LYS B  1 365 ? -2.61691 39.30438  1.52213   1.000 23.96221 ? 396  LYS B CG  1 
ATOM   6513 C  CD  . LYS B  1 365 ? -3.89511 39.53115  0.73983   1.000 36.93472 ? 396  LYS B CD  1 
ATOM   6514 C  CE  . LYS B  1 365 ? -3.61947 40.02352  -0.66235  1.000 44.03088 ? 396  LYS B CE  1 
ATOM   6515 N  NZ  . LYS B  1 365 ? -4.72835 40.90414  -1.14438  1.000 50.45244 ? 396  LYS B NZ  1 
ATOM   6516 N  N   . ASN B  1 366 ? 0.23104  35.43851  2.29861   1.000 18.82647 ? 397  ASN B N   1 
ATOM   6517 C  CA  . ASN B  1 366 ? 0.48398  33.99982  2.19797   1.000 19.25243 ? 397  ASN B CA  1 
ATOM   6518 C  C   . ASN B  1 366 ? -0.46218 33.32768  1.20199   1.000 19.25855 ? 397  ASN B C   1 
ATOM   6519 O  O   . ASN B  1 366 ? -1.09969 32.31592  1.50143   1.000 21.63966 ? 397  ASN B O   1 
ATOM   6520 C  CB  . ASN B  1 366 ? 0.39715  33.32142  3.56441   1.000 21.63046 ? 397  ASN B CB  1 
ATOM   6521 C  CG  . ASN B  1 366 ? 1.04263  31.94436  3.56545   1.000 24.59275 ? 397  ASN B CG  1 
ATOM   6522 O  OD1 . ASN B  1 366 ? 2.14270  31.76570  3.03301   1.000 23.76520 ? 397  ASN B OD1 1 
ATOM   6523 N  ND2 . ASN B  1 366 ? 0.35888  30.96102  4.15122   1.000 24.09574 ? 397  ASN B ND2 1 
ATOM   6524 N  N   . THR B  1 367 ? -0.55342 33.90276  0.00372   1.000 20.24772 ? 398  THR B N   1 
ATOM   6525 C  CA  . THR B  1 367 ? -1.30447 33.31025  -1.09299  1.000 20.64455 ? 398  THR B CA  1 
ATOM   6526 C  C   . THR B  1 367 ? -0.34580 32.86588  -2.19362  1.000 21.05155 ? 398  THR B C   1 
ATOM   6527 O  O   . THR B  1 367 ? 0.82398  33.25463  -2.21646  1.000 20.33371 ? 398  THR B O   1 
ATOM   6528 C  CB  . THR B  1 367 ? -2.35504 34.28655  -1.64995  1.000 24.36864 ? 398  THR B CB  1 
ATOM   6529 O  OG1 . THR B  1 367 ? -1.73799 35.50838  -2.07590  1.000 24.00659 ? 398  THR B OG1 1 
ATOM   6530 C  CG2 . THR B  1 367 ? -3.40883 34.59330  -0.58762  1.000 25.84963 ? 398  THR B CG2 1 
ATOM   6531 N  N   . GLU B  1 368 ? -0.85436 32.03192  -3.10605  1.000 19.38638 ? 399  GLU B N   1 
ATOM   6532 C  CA  . GLU B  1 368 ? -0.03221 31.26530  -4.04269  1.000 18.15234 ? 399  GLU B CA  1 
ATOM   6533 C  C   . GLU B  1 368 ? 0.06408  31.97131  -5.39599  1.000 20.22922 ? 399  GLU B C   1 
ATOM   6534 O  O   . GLU B  1 368 ? -0.86953 31.86893  -6.20999  1.000 22.15961 ? 399  GLU B O   1 
ATOM   6535 C  CB  . GLU B  1 368 ? -0.62428 29.85904  -4.20982  1.000 16.76892 ? 399  GLU B CB  1 
ATOM   6536 C  CG  . GLU B  1 368 ? 0.16581  28.93117  -5.12746  1.000 19.34155 ? 399  GLU B CG  1 
ATOM   6537 C  CD  . GLU B  1 368 ? -0.49053 27.56741  -5.29274  1.000 23.41089 ? 399  GLU B CD  1 
ATOM   6538 O  OE1 . GLU B  1 368 ? -1.62643 27.37903  -4.79800  1.000 27.88653 ? 399  GLU B OE1 1 
ATOM   6539 O  OE2 . GLU B  1 368 ? 0.12551  26.68186  -5.91683  1.000 23.30186 ? 399  GLU B OE2 1 
ATOM   6540 N  N   . PRO B  1 369 ? 1.16333  32.67481  -5.70099  1.000 17.82119 ? 400  PRO B N   1 
ATOM   6541 C  CA  . PRO B  1 369 ? 1.19291  33.45464  -6.95190  1.000 19.77263 ? 400  PRO B CA  1 
ATOM   6542 C  C   . PRO B  1 369 ? 1.11843  32.59981  -8.20215  1.000 19.76644 ? 400  PRO B C   1 
ATOM   6543 O  O   . PRO B  1 369 ? 0.51363  33.02594  -9.19328  1.000 21.62432 ? 400  PRO B O   1 
ATOM   6544 C  CB  . PRO B  1 369 ? 2.52577  34.21580  -6.86672  1.000 17.54261 ? 400  PRO B CB  1 
ATOM   6545 C  CG  . PRO B  1 369 ? 3.36593  33.42276  -5.90463  1.000 20.70085 ? 400  PRO B CG  1 
ATOM   6546 C  CD  . PRO B  1 369 ? 2.39012  32.86650  -4.90018  1.000 16.87495 ? 400  PRO B CD  1 
ATOM   6547 N  N   . TYR B  1 370 ? 1.73157  31.41618  -8.20409  1.000 19.60493 ? 401  TYR B N   1 
ATOM   6548 C  CA  . TYR B  1 370 ? 1.75744  30.58259  -9.39710  1.000 19.61007 ? 401  TYR B CA  1 
ATOM   6549 C  C   . TYR B  1 370 ? 0.72364  29.46864  -9.33982  1.000 18.50813 ? 401  TYR B C   1 
ATOM   6550 O  O   . TYR B  1 370 ? 0.92512  28.40599  -9.92785  1.000 19.21939 ? 401  TYR B O   1 
ATOM   6551 C  CB  . TYR B  1 370 ? 3.16416  30.01946  -9.62848  1.000 17.39989 ? 401  TYR B CB  1 
ATOM   6552 C  CG  . TYR B  1 370 ? 4.10295  31.06831  -10.18115 1.000 18.84284 ? 401  TYR B CG  1 
ATOM   6553 C  CD1 . TYR B  1 370 ? 4.79480  31.93195  -9.33753  1.000 19.44336 ? 401  TYR B CD1 1 
ATOM   6554 C  CD2 . TYR B  1 370 ? 4.24376  31.23792  -11.55747 1.000 19.50426 ? 401  TYR B CD2 1 
ATOM   6555 C  CE1 . TYR B  1 370 ? 5.64119  32.92179  -9.85294  1.000 17.92479 ? 401  TYR B CE1 1 
ATOM   6556 C  CE2 . TYR B  1 370 ? 5.07558  32.20914  -12.08054 1.000 20.01946 ? 401  TYR B CE2 1 
ATOM   6557 C  CZ  . TYR B  1 370 ? 5.76711  33.04924  -11.22916 1.000 18.18859 ? 401  TYR B CZ  1 
ATOM   6558 O  OH  . TYR B  1 370 ? 6.59256  34.00155  -11.77843 1.000 19.44645 ? 401  TYR B OH  1 
ATOM   6559 N  N   . LYS B  1 371 ? -0.39307 29.70058  -8.64672  1.000 19.95837 ? 402  LYS B N   1 
ATOM   6560 C  CA  . LYS B  1 371 ? -1.47803 28.72098  -8.63250  1.000 20.29445 ? 402  LYS B CA  1 
ATOM   6561 C  C   . LYS B  1 371 ? -1.87384 28.34246  -10.05421 1.000 19.23276 ? 402  LYS B C   1 
ATOM   6562 O  O   . LYS B  1 371 ? -2.18913 29.21220  -10.87727 1.000 21.14901 ? 402  LYS B O   1 
ATOM   6563 C  CB  . LYS B  1 371 ? -2.68483 29.28617  -7.87569  1.000 21.05446 ? 402  LYS B CB  1 
ATOM   6564 C  CG  . LYS B  1 371 ? -3.81132 28.25888  -7.70669  1.000 23.95168 ? 402  LYS B CG  1 
ATOM   6565 C  CD  . LYS B  1 371 ? -5.09833 28.90573  -7.21679  1.000 31.00919 ? 402  LYS B CD  1 
ATOM   6566 C  CE  . LYS B  1 371 ? -4.93319 29.53537  -5.84359  1.000 34.00275 ? 402  LYS B CE  1 
ATOM   6567 N  NZ  . LYS B  1 371 ? -6.15401 30.32508  -5.45709  1.000 38.59105 ? 402  LYS B NZ  1 
ATOM   6568 N  N   . ASP B  1 372 ? -1.82603 27.04002  -10.34113 1.000 21.07738 ? 403  ASP B N   1 
ATOM   6569 C  CA  . ASP B  1 372 ? -2.19181 26.46129  -11.63753 1.000 21.38955 ? 403  ASP B CA  1 
ATOM   6570 C  C   . ASP B  1 372 ? -1.30991 26.96663  -12.77005 1.000 21.02629 ? 403  ASP B C   1 
ATOM   6571 O  O   . ASP B  1 372 ? -1.71648 26.93580  -13.93489 1.000 23.32653 ? 403  ASP B O   1 
ATOM   6572 C  CB  . ASP B  1 372 ? -3.66462 26.71872  -11.99417 1.000 21.81259 ? 403  ASP B CB  1 
ATOM   6573 C  CG  . ASP B  1 372 ? -4.62474 26.23546  -10.92486 1.000 26.43128 ? 403  ASP B CG  1 
ATOM   6574 O  OD1 . ASP B  1 372 ? -4.37290 25.17691  -10.32205 1.000 23.18088 ? 403  ASP B OD1 1 
ATOM   6575 O  OD2 . ASP B  1 372 ? -5.63420 26.93224  -10.69028 1.000 26.86288 ? 403  ASP B OD2 1 
ATOM   6576 N  N   . GLU B  1 373 ? -0.10130 27.42147  -12.45860 1.000 19.12709 ? 404  GLU B N   1 
ATOM   6577 C  CA  . GLU B  1 373 ? 0.81685  27.93443  -13.46136 1.000 19.22179 ? 404  GLU B CA  1 
ATOM   6578 C  C   . GLU B  1 373 ? 2.19439  27.32208  -13.24383 1.000 19.66916 ? 404  GLU B C   1 
ATOM   6579 O  O   . GLU B  1 373 ? 2.49333  26.76133  -12.18369 1.000 22.14743 ? 404  GLU B O   1 
ATOM   6580 C  CB  . GLU B  1 373 ? 0.89356  29.46760  -13.43276 1.000 18.53788 ? 404  GLU B CB  1 
ATOM   6581 C  CG  . GLU B  1 373 ? -0.41700 30.15216  -13.81415 1.000 21.72223 ? 404  GLU B CG  1 
ATOM   6582 C  CD  . GLU B  1 373 ? -0.29183 31.65999  -13.83887 1.000 30.61666 ? 404  GLU B CD  1 
ATOM   6583 O  OE1 . GLU B  1 373 ? 0.79698  32.16001  -14.18103 1.000 33.24993 ? 404  GLU B OE1 1 
ATOM   6584 O  OE2 . GLU B  1 373 ? -1.27917 32.35376  -13.50930 1.000 40.26644 ? 404  GLU B OE2 1 
ATOM   6585 N  N   . MET B  1 374 ? 3.02981  27.44409  -14.27125 1.000 18.52829 ? 405  MET B N   1 
ATOM   6586 C  CA  . MET B  1 374 ? 4.30788  26.75306  -14.34730 1.000 19.46898 ? 405  MET B CA  1 
ATOM   6587 C  C   . MET B  1 374 ? 5.47619  27.66837  -14.01040 1.000 18.77983 ? 405  MET B C   1 
ATOM   6588 O  O   . MET B  1 374 ? 5.47008  28.85581  -14.34219 1.000 19.23924 ? 405  MET B O   1 
ATOM   6589 C  CB  . MET B  1 374 ? 4.51813  26.20124  -15.75632 1.000 20.52158 ? 405  MET B CB  1 
ATOM   6590 C  CG  . MET B  1 374 ? 3.66672  25.01786  -16.10832 1.000 22.85795 ? 405  MET B CG  1 
ATOM   6591 S  SD  . MET B  1 374 ? 4.33447  23.53623  -15.35191 1.000 25.17713 ? 405  MET B SD  1 
ATOM   6592 C  CE  . MET B  1 374 ? 3.94443  22.32873  -16.61936 1.000 26.09760 ? 405  MET B CE  1 
ATOM   6593 N  N   . ILE B  1 375 ? 6.48394  27.08783  -13.37132 1.000 18.42604 ? 406  ILE B N   1 
ATOM   6594 C  CA  . ILE B  1 375 ? 7.82936  27.64092  -13.30164 1.000 17.34421 ? 406  ILE B CA  1 
ATOM   6595 C  C   . ILE B  1 375 ? 8.73862  26.64021  -14.00786 1.000 17.53321 ? 406  ILE B C   1 
ATOM   6596 O  O   . ILE B  1 375 ? 8.65941  25.43352  -13.74968 1.000 18.76186 ? 406  ILE B O   1 
ATOM   6597 C  CB  . ILE B  1 375 ? 8.25726  27.89866  -11.84574 1.000 18.04672 ? 406  ILE B CB  1 
ATOM   6598 C  CG1 . ILE B  1 375 ? 7.50924  29.12889  -11.31585 1.000 19.96689 ? 406  ILE B CG1 1 
ATOM   6599 C  CG2 . ILE B  1 375 ? 9.77596  28.09163  -11.73753 1.000 20.52609 ? 406  ILE B CG2 1 
ATOM   6600 C  CD1 . ILE B  1 375 ? 7.67234  29.38563  -9.83685  1.000 22.05458 ? 406  ILE B CD1 1 
ATOM   6601 N  N   . TYR B  1 376 ? 9.56841  27.13692  -14.92831 1.000 17.37140 ? 407  TYR B N   1 
ATOM   6602 C  CA  . TYR B  1 376 ? 10.22493 26.31241  -15.93223 1.000 19.81446 ? 407  TYR B CA  1 
ATOM   6603 C  C   . TYR B  1 376 ? 11.73925 26.43138  -15.87255 1.000 18.72934 ? 407  TYR B C   1 
ATOM   6604 O  O   . TYR B  1 376 ? 12.28464 27.46606  -15.47992 1.000 18.96373 ? 407  TYR B O   1 
ATOM   6605 C  CB  . TYR B  1 376 ? 9.85081  26.74667  -17.34479 1.000 21.16580 ? 407  TYR B CB  1 
ATOM   6606 C  CG  . TYR B  1 376 ? 8.44010  26.57755  -17.79028 1.000 18.83233 ? 407  TYR B CG  1 
ATOM   6607 C  CD1 . TYR B  1 376 ? 7.91051  25.31244  -17.99618 1.000 24.51249 ? 407  TYR B CD1 1 
ATOM   6608 C  CD2 . TYR B  1 376 ? 7.66325  27.68669  -18.10992 1.000 21.49361 ? 407  TYR B CD2 1 
ATOM   6609 C  CE1 . TYR B  1 376 ? 6.62884  25.14909  -18.45564 1.000 24.43152 ? 407  TYR B CE1 1 
ATOM   6610 C  CE2 . TYR B  1 376 ? 6.37258  27.52845  -18.57797 1.000 23.37981 ? 407  TYR B CE2 1 
ATOM   6611 C  CZ  . TYR B  1 376 ? 5.87264  26.25724  -18.74951 1.000 24.07779 ? 407  TYR B CZ  1 
ATOM   6612 O  OH  . TYR B  1 376 ? 4.59327  26.08094  -19.21067 1.000 27.43076 ? 407  TYR B OH  1 
ATOM   6613 N  N   . SER B  1 377 ? 12.40391 25.38955  -16.37095 1.000 17.51193 ? 408  SER B N   1 
ATOM   6614 C  CA  . SER B  1 377 ? 13.79318 25.50267  -16.79084 1.000 19.46754 ? 408  SER B CA  1 
ATOM   6615 C  C   . SER B  1 377 ? 14.03917 24.61781  -18.00419 1.000 18.92967 ? 408  SER B C   1 
ATOM   6616 O  O   . SER B  1 377 ? 13.54904 23.48539  -18.07820 1.000 16.42002 ? 408  SER B O   1 
ATOM   6617 C  CB  . SER B  1 377 ? 14.76507 25.12936  -15.66873 1.000 18.51157 ? 408  SER B CB  1 
ATOM   6618 O  OG  . SER B  1 377 ? 16.11525 25.29697  -16.11031 1.000 21.21729 ? 408  SER B OG  1 
ATOM   6619 N  N   . LEU B  1 378 ? 14.80905 25.14067  -18.95766 1.000 17.78277 ? 409  LEU B N   1 
ATOM   6620 C  CA  . LEU B  1 378 ? 15.30752 24.32145  -20.05001 1.000 16.71292 ? 409  LEU B CA  1 
ATOM   6621 C  C   . LEU B  1 378 ? 16.75805 24.70841  -20.26946 1.000 16.40638 ? 409  LEU B C   1 
ATOM   6622 O  O   . LEU B  1 378 ? 17.06161 25.88719  -20.46988 1.000 17.10909 ? 409  LEU B O   1 
ATOM   6623 C  CB  . LEU B  1 378 ? 14.48128 24.50572  -21.33310 1.000 19.15108 ? 409  LEU B CB  1 
ATOM   6624 C  CG  . LEU B  1 378 ? 14.86131 23.56917  -22.49531 1.000 16.60606 ? 409  LEU B CG  1 
ATOM   6625 C  CD1 . LEU B  1 378 ? 13.63859 23.19952  -23.32367 1.000 18.93905 ? 409  LEU B CD1 1 
ATOM   6626 C  CD2 . LEU B  1 378 ? 15.93113 24.17323  -23.40398 1.000 18.60678 ? 409  LEU B CD2 1 
ATOM   6627 N  N   . ARG B  1 379 ? 17.65070 23.72708  -20.20047 1.000 15.62528 ? 410  ARG B N   1 
ATOM   6628 C  CA  . ARG B  1 379 ? 19.08372 23.95684  -20.33199 1.000 16.51694 ? 410  ARG B CA  1 
ATOM   6629 C  C   . ARG B  1 379 ? 19.60218 23.15690  -21.52096 1.000 17.16126 ? 410  ARG B C   1 
ATOM   6630 O  O   . ARG B  1 379 ? 19.40105 21.93615  -21.60233 1.000 18.11090 ? 410  ARG B O   1 
ATOM   6631 C  CB  . ARG B  1 379 ? 19.81451 23.59285  -19.03039 1.000 16.40733 ? 410  ARG B CB  1 
ATOM   6632 C  CG  . ARG B  1 379 ? 21.32752 23.79397  -19.09076 1.000 16.20554 ? 410  ARG B CG  1 
ATOM   6633 C  CD  . ARG B  1 379 ? 22.06162 22.48215  -19.35165 1.000 15.36469 ? 410  ARG B CD  1 
ATOM   6634 N  NE  . ARG B  1 379 ? 23.42655 22.70211  -19.82782 1.000 17.26018 ? 410  ARG B NE  1 
ATOM   6635 C  CZ  . ARG B  1 379 ? 24.44999 23.04339  -19.05650 1.000 17.41727 ? 410  ARG B CZ  1 
ATOM   6636 N  NH1 . ARG B  1 379 ? 24.31434 23.19664  -17.74518 1.000 18.76225 ? 410  ARG B NH1 1 
ATOM   6637 N  NH2 . ARG B  1 379 ? 25.64454 23.24281  -19.61108 1.000 17.25032 ? 410  ARG B NH2 1 
ATOM   6638 N  N   . TYR B  1 380 ? 20.24672 23.85324  -22.45702 1.000 18.45062 ? 411  TYR B N   1 
ATOM   6639 C  CA  . TYR B  1 380 ? 20.75110 23.19192  -23.65221 1.000 18.28024 ? 411  TYR B CA  1 
ATOM   6640 C  C   . TYR B  1 380 ? 21.96832 22.33622  -23.31781 1.000 17.60456 ? 411  TYR B C   1 
ATOM   6641 O  O   . TYR B  1 380 ? 22.86703 22.75322  -22.57840 1.000 18.05411 ? 411  TYR B O   1 
ATOM   6642 C  CB  . TYR B  1 380 ? 21.09586 24.23248  -24.72329 1.000 19.00874 ? 411  TYR B CB  1 
ATOM   6643 C  CG  . TYR B  1 380 ? 19.91369 25.07573  -25.17461 1.000 18.74634 ? 411  TYR B CG  1 
ATOM   6644 C  CD1 . TYR B  1 380 ? 18.86835 24.51282  -25.89713 1.000 17.20733 ? 411  TYR B CD1 1 
ATOM   6645 C  CD2 . TYR B  1 380 ? 19.84857 26.43347  -24.88345 1.000 21.36188 ? 411  TYR B CD2 1 
ATOM   6646 C  CE1 . TYR B  1 380 ? 17.78227 25.27394  -26.30529 1.000 17.10165 ? 411  TYR B CE1 1 
ATOM   6647 C  CE2 . TYR B  1 380 ? 18.76122 27.20427  -25.29244 1.000 21.99364 ? 411  TYR B CE2 1 
ATOM   6648 C  CZ  . TYR B  1 380 ? 17.74044 26.61918  -26.00844 1.000 20.13911 ? 411  TYR B CZ  1 
ATOM   6649 O  OH  . TYR B  1 380 ? 16.66524 27.39361  -26.41470 1.000 22.19329 ? 411  TYR B OH  1 
ATOM   6650 N  N   . ARG B  1 381 ? 21.98392 21.12344  -23.85272 1.000 17.18155 ? 412  ARG B N   1 
ATOM   6651 C  CA  . ARG B  1 381 ? 23.12197 20.21801  -23.74267 1.000 18.56553 ? 412  ARG B CA  1 
ATOM   6652 C  C   . ARG B  1 381 ? 23.68908 19.96564  -25.13718 1.000 19.55380 ? 412  ARG B C   1 
ATOM   6653 O  O   . ARG B  1 381 ? 23.25019 20.55383  -26.12567 1.000 18.03218 ? 412  ARG B O   1 
ATOM   6654 C  CB  . ARG B  1 381 ? 22.70924 18.91109  -23.06293 1.000 17.45399 ? 412  ARG B CB  1 
ATOM   6655 C  CG  . ARG B  1 381 ? 22.32389 19.09064  -21.59312 1.000 17.10449 ? 412  ARG B CG  1 
ATOM   6656 C  CD  . ARG B  1 381 ? 23.54773 19.34015  -20.73948 1.000 16.40095 ? 412  ARG B CD  1 
ATOM   6657 N  NE  . ARG B  1 381 ? 23.16795 19.44854  -19.33328 1.000 16.71358 ? 412  ARG B NE  1 
ATOM   6658 C  CZ  . ARG B  1 381 ? 24.02498 19.70435  -18.35728 1.000 19.21175 ? 412  ARG B CZ  1 
ATOM   6659 N  NH1 . ARG B  1 381 ? 25.31251 19.90068  -18.60208 1.000 18.27756 ? 412  ARG B NH1 1 
ATOM   6660 N  NH2 . ARG B  1 381 ? 23.58044 19.75652  -17.10107 1.000 19.08507 ? 412  ARG B NH2 1 
ATOM   6661 N  N   . GLU B  1 382 ? 24.66493 19.06395  -25.21911 1.000 18.89902 ? 413  GLU B N   1 
ATOM   6662 C  CA  . GLU B  1 382 ? 25.30681 18.78915  -26.50453 1.000 18.07764 ? 413  GLU B CA  1 
ATOM   6663 C  C   . GLU B  1 382 ? 24.47931 17.74112  -27.23833 1.000 17.84674 ? 413  GLU B C   1 
ATOM   6664 O  O   . GLU B  1 382 ? 24.77616 16.54680  -27.24024 1.000 20.67656 ? 413  GLU B O   1 
ATOM   6665 C  CB  . GLU B  1 382 ? 26.75202 18.35307  -26.30740 1.000 19.33138 ? 413  GLU B CB  1 
ATOM   6666 C  CG  . GLU B  1 382 ? 27.56432 19.32054  -25.45760 1.000 22.99345 ? 413  GLU B CG  1 
ATOM   6667 C  CD  . GLU B  1 382 ? 27.36478 20.76538  -25.88001 1.000 28.09275 ? 413  GLU B CD  1 
ATOM   6668 O  OE1 . GLU B  1 382 ? 27.46194 21.04171  -27.10039 1.000 26.46056 ? 413  GLU B OE1 1 
ATOM   6669 O  OE2 . GLU B  1 382 ? 27.10025 21.61705  -24.99638 1.000 26.92888 ? 413  GLU B OE2 1 
ATOM   6670 N  N   . GLY B  1 383 ? 23.40947 18.21377  -27.87529 1.000 20.11344 ? 414  GLY B N   1 
ATOM   6671 C  CA  . GLY B  1 383 ? 22.57036 17.37354  -28.70331 1.000 18.90979 ? 414  GLY B CA  1 
ATOM   6672 C  C   . GLY B  1 383 ? 21.19813 17.06515  -28.14298 1.000 20.59963 ? 414  GLY B C   1 
ATOM   6673 O  O   . GLY B  1 383 ? 20.41783 16.37605  -28.81310 1.000 22.70993 ? 414  GLY B O   1 
ATOM   6674 N  N   . TYR B  1 384 ? 20.87628 17.54245  -26.94561 1.000 19.16859 ? 415  TYR B N   1 
ATOM   6675 C  CA  . TYR B  1 384 ? 19.57392 17.30561  -26.32881 1.000 16.14046 ? 415  TYR B CA  1 
ATOM   6676 C  C   . TYR B  1 384 ? 19.35287 18.42815  -25.31465 1.000 17.75763 ? 415  TYR B C   1 
ATOM   6677 O  O   . TYR B  1 384 ? 20.22062 19.28449  -25.11736 1.000 17.93905 ? 415  TYR B O   1 
ATOM   6678 C  CB  . TYR B  1 384 ? 19.51547 15.89971  -25.70722 1.000 18.67257 ? 415  TYR B CB  1 
ATOM   6679 C  CG  . TYR B  1 384 ? 20.45153 15.75828  -24.54063 1.000 17.48272 ? 415  TYR B CG  1 
ATOM   6680 C  CD1 . TYR B  1 384 ? 21.78633 15.42554  -24.72713 1.000 17.41428 ? 415  TYR B CD1 1 
ATOM   6681 C  CD2 . TYR B  1 384 ? 20.00550 15.99826  -23.25044 1.000 16.29359 ? 415  TYR B CD2 1 
ATOM   6682 C  CE1 . TYR B  1 384 ? 22.66516 15.33199  -23.63881 1.000 16.71899 ? 415  TYR B CE1 1 
ATOM   6683 C  CE2 . TYR B  1 384 ? 20.87088 15.91853  -22.16448 1.000 16.23679 ? 415  TYR B CE2 1 
ATOM   6684 C  CZ  . TYR B  1 384 ? 22.18576 15.57622  -22.36069 1.000 18.57020 ? 415  TYR B CZ  1 
ATOM   6685 O  OH  . TYR B  1 384 ? 23.04083 15.49185  -21.28345 1.000 16.55647 ? 415  TYR B OH  1 
ATOM   6686 N  N   . ASN B  1 385 ? 18.17785 18.43263  -24.68093 1.000 17.44149 ? 416  ASN B N   1 
ATOM   6687 C  CA  . ASN B  1 385 ? 17.82103 19.44608  -23.69894 1.000 17.69801 ? 416  ASN B CA  1 
ATOM   6688 C  C   . ASN B  1 385 ? 17.47055 18.80305  -22.36491 1.000 16.24472 ? 416  ASN B C   1 
ATOM   6689 O  O   . ASN B  1 385 ? 16.76465 17.78772  -22.31456 1.000 17.13722 ? 416  ASN B O   1 
ATOM   6690 C  CB  . ASN B  1 385 ? 16.63054 20.28160  -24.18218 1.000 19.35498 ? 416  ASN B CB  1 
ATOM   6691 C  CG  . ASN B  1 385 ? 16.89226 20.92614  -25.51980 1.000 19.12177 ? 416  ASN B CG  1 
ATOM   6692 O  OD1 . ASN B  1 385 ? 17.93168 21.55008  -25.71005 1.000 19.79208 ? 416  ASN B OD1 1 
ATOM   6693 N  ND2 . ASN B  1 385 ? 15.95927 20.75862  -26.46273 1.000 18.95588 ? 416  ASN B ND2 1 
ATOM   6694 N  N   . ASP B  1 386 ? 17.97413 19.40060  -21.28402 1.000 16.37789 ? 417  ASP B N   1 
ATOM   6695 C  CA  . ASP B  1 386 ? 17.47133 19.12648  -19.94220 1.000 17.44353 ? 417  ASP B CA  1 
ATOM   6696 C  C   . ASP B  1 386 ? 16.29737 20.05770  -19.64469 1.000 15.54069 ? 417  ASP B C   1 
ATOM   6697 O  O   . ASP B  1 386 ? 16.31952 21.23405  -20.01562 1.000 17.38674 ? 417  ASP B O   1 
ATOM   6698 C  CB  . ASP B  1 386 ? 18.57368 19.34483  -18.90048 1.000 16.64370 ? 417  ASP B CB  1 
ATOM   6699 C  CG  . ASP B  1 386 ? 19.66609 18.28590  -18.95240 1.000 17.47647 ? 417  ASP B CG  1 
ATOM   6700 O  OD1 . ASP B  1 386 ? 19.40694 17.16435  -19.42699 1.000 17.16838 ? 417  ASP B OD1 1 
ATOM   6701 O  OD2 . ASP B  1 386 ? 20.78805 18.58492  -18.47730 1.000 16.54051 ? 417  ASP B OD2 1 
ATOM   6702 N  N   . VAL B  1 387 ? 15.26572 19.52805  -18.98126 1.000 15.41335 ? 418  VAL B N   1 
ATOM   6703 C  CA  . VAL B  1 387 ? 14.05215 20.28823  -18.69176 1.000 15.48462 ? 418  VAL B CA  1 
ATOM   6704 C  C   . VAL B  1 387 ? 13.61430 20.06141  -17.24711 1.000 16.93297 ? 418  VAL B C   1 
ATOM   6705 O  O   . VAL B  1 387 ? 13.77935 18.97406  -16.68420 1.000 16.09029 ? 418  VAL B O   1 
ATOM   6706 C  CB  . VAL B  1 387 ? 12.89754 19.90730  -19.65140 1.000 16.99724 ? 418  VAL B CB  1 
ATOM   6707 C  CG1 . VAL B  1 387 ? 11.66775 20.80328  -19.43268 1.000 19.59764 ? 418  VAL B CG1 1 
ATOM   6708 C  CG2 . VAL B  1 387 ? 13.36186 19.97433  -21.10646 1.000 19.51015 ? 418  VAL B CG2 1 
ATOM   6709 N  N   . GLY B  1 388 ? 13.05026 21.10428  -16.65613 1.000 17.26631 ? 419  GLY B N   1 
ATOM   6710 C  CA  . GLY B  1 388 ? 12.26150 20.96202  -15.44396 1.000 15.71010 ? 419  GLY B CA  1 
ATOM   6711 C  C   . GLY B  1 388 ? 11.04220 21.85674  -15.54194 1.000 16.52749 ? 419  GLY B C   1 
ATOM   6712 O  O   . GLY B  1 388 ? 11.08953 22.93095  -16.13188 1.000 17.65288 ? 419  GLY B O   1 
ATOM   6713 N  N   . ALA B  1 389 ? 9.92919  21.39963  -14.96888 1.000 17.41291 ? 420  ALA B N   1 
ATOM   6714 C  CA  . ALA B  1 389 ? 8.73350  22.23599  -14.97049 1.000 17.88170 ? 420  ALA B CA  1 
ATOM   6715 C  C   . ALA B  1 389 ? 7.89934  21.90070  -13.74625 1.000 18.33136 ? 420  ALA B C   1 
ATOM   6716 O  O   . ALA B  1 389 ? 7.57129  20.73330  -13.53172 1.000 19.84044 ? 420  ALA B O   1 
ATOM   6717 C  CB  . ALA B  1 389 ? 7.90981  22.03740  -16.25462 1.000 18.23215 ? 420  ALA B CB  1 
ATOM   6718 N  N   . ARG B  1 390 ? 7.56712  22.91541  -12.95207 1.000 17.49245 ? 421  ARG B N   1 
ATOM   6719 C  CA  . ARG B  1 390 ? 6.82855  22.72208  -11.70811 1.000 18.00975 ? 421  ARG B CA  1 
ATOM   6720 C  C   . ARG B  1 390 ? 5.49043  23.44937  -11.72162 1.000 17.46522 ? 421  ARG B C   1 
ATOM   6721 O  O   . ARG B  1 390 ? 5.41990  24.64161  -12.04535 1.000 18.06173 ? 421  ARG B O   1 
ATOM   6722 C  CB  . ARG B  1 390 ? 7.63013  23.22107  -10.50840 1.000 16.16416 ? 421  ARG B CB  1 
ATOM   6723 C  CG  . ARG B  1 390 ? 6.83211  23.07377  -9.21133  1.000 17.38855 ? 421  ARG B CG  1 
ATOM   6724 C  CD  . ARG B  1 390 ? 7.63462  23.42359  -7.99039  1.000 17.86693 ? 421  ARG B CD  1 
ATOM   6725 N  NE  . ARG B  1 390 ? 6.78594  23.29230  -6.80538  1.000 17.86202 ? 421  ARG B NE  1 
ATOM   6726 C  CZ  . ARG B  1 390 ? 7.21723  23.45257  -5.56410  1.000 17.46703 ? 421  ARG B CZ  1 
ATOM   6727 N  NH1 . ARG B  1 390 ? 8.49986  23.67296  -5.30117  1.000 17.65769 ? 421  ARG B NH1 1 
ATOM   6728 N  NH2 . ARG B  1 390 ? 6.34152  23.39148  -4.56029  1.000 17.19397 ? 421  ARG B NH2 1 
ATOM   6729 N  N   . MET B  1 391 ? 4.43378  22.73997  -11.32845 1.000 18.09246 ? 422  MET B N   1 
ATOM   6730 C  CA  A MET B  1 391 ? 3.14069  23.36514  -11.07713 0.618 20.66851 ? 422  MET B CA  1 
ATOM   6731 C  CA  B MET B  1 391 ? 3.12302  23.34154  -11.09990 0.382 20.67429 ? 422  MET B CA  1 
ATOM   6732 C  C   . MET B  1 391 ? 2.61668  22.82361  -9.76003  1.000 18.37797 ? 422  MET B C   1 
ATOM   6733 O  O   . MET B  1 391 ? 2.39623  21.62014  -9.62000  1.000 20.68347 ? 422  MET B O   1 
ATOM   6734 C  CB  A MET B  1 391 ? 2.13459  23.11155  -12.20230 0.618 21.97342 ? 422  MET B CB  1 
ATOM   6735 C  CB  B MET B  1 391 ? 2.16461  22.98469  -12.23694 0.382 21.91930 ? 422  MET B CB  1 
ATOM   6736 C  CG  A MET B  1 391 ? 0.82398  23.85361  -11.97017 0.618 20.07335 ? 422  MET B CG  1 
ATOM   6737 C  CG  B MET B  1 391 ? 0.72460  23.39904  -12.02905 0.382 20.93893 ? 422  MET B CG  1 
ATOM   6738 S  SD  A MET B  1 391 ? -0.39819 23.64213  -13.27571 0.618 24.15855 ? 422  MET B SD  1 
ATOM   6739 S  SD  B MET B  1 391 ? -0.32949 22.65923  -13.29519 0.382 26.63021 ? 422  MET B SD  1 
ATOM   6740 C  CE  A MET B  1 391 ? 0.46847  24.39799  -14.63909 0.618 22.55842 ? 422  MET B CE  1 
ATOM   6741 C  CE  B MET B  1 391 ? 0.31182  23.44108  -14.77397 0.382 23.65838 ? 422  MET B CE  1 
ATOM   6742 N  N   . GLY B  1 392 ? 2.46100  23.71392  -8.78121  1.000 19.31237 ? 423  GLY B N   1 
ATOM   6743 C  CA  . GLY B  1 392 ? 1.97808  23.26846  -7.48081  1.000 20.29599 ? 423  GLY B CA  1 
ATOM   6744 C  C   . GLY B  1 392 ? 2.94306  22.27089  -6.87823  1.000 21.62034 ? 423  GLY B C   1 
ATOM   6745 O  O   . GLY B  1 392 ? 4.15891  22.48861  -6.86132  1.000 20.61456 ? 423  GLY B O   1 
ATOM   6746 N  N   . ASP B  1 393 ? 2.40828  21.14565  -6.39523  1.000 17.89727 ? 424  ASP B N   1 
ATOM   6747 C  CA  . ASP B  1 393 ? 3.22605  20.12243  -5.75639  1.000 17.71853 ? 424  ASP B CA  1 
ATOM   6748 C  C   . ASP B  1 393 ? 3.97069  19.23557  -6.73616  1.000 18.29244 ? 424  ASP B C   1 
ATOM   6749 O  O   . ASP B  1 393 ? 4.69873  18.34621  -6.28835  1.000 18.79996 ? 424  ASP B O   1 
ATOM   6750 C  CB  . ASP B  1 393 ? 2.36292  19.21986  -4.86903  1.000 19.15571 ? 424  ASP B CB  1 
ATOM   6751 C  CG  . ASP B  1 393 ? 1.80531  19.94068  -3.65791  1.000 22.84868 ? 424  ASP B CG  1 
ATOM   6752 O  OD1 . ASP B  1 393 ? 2.53092  20.72506  -3.01820  1.000 22.58057 ? 424  ASP B OD1 1 
ATOM   6753 O  OD2 . ASP B  1 393 ? 0.62505  19.69774  -3.33289  1.000 28.07648 ? 424  ASP B OD2 1 
ATOM   6754 N  N   . TRP B  1 394 ? 3.79294  19.42407  -8.04212  1.000 19.38727 ? 425  TRP B N   1 
ATOM   6755 C  CA  . TRP B  1 394 ? 4.24471  18.45887  -9.03363  1.000 19.38658 ? 425  TRP B CA  1 
ATOM   6756 C  C   . TRP B  1 394 ? 5.34653  19.03538  -9.90644  1.000 18.29602 ? 425  TRP B C   1 
ATOM   6757 O  O   . TRP B  1 394 ? 5.32608  20.21846  -10.24609 1.000 18.41253 ? 425  TRP B O   1 
ATOM   6758 C  CB  . TRP B  1 394 ? 3.08253  18.01321  -9.91426  1.000 19.71878 ? 425  TRP B CB  1 
ATOM   6759 C  CG  . TRP B  1 394 ? 2.02567  17.32837  -9.10664  1.000 19.98781 ? 425  TRP B CG  1 
ATOM   6760 C  CD1 . TRP B  1 394 ? 0.92134  17.90343  -8.53912  1.000 23.76554 ? 425  TRP B CD1 1 
ATOM   6761 C  CD2 . TRP B  1 394 ? 1.99973  15.95168  -8.73634  1.000 20.30707 ? 425  TRP B CD2 1 
ATOM   6762 N  NE1 . TRP B  1 394 ? 0.20039  16.95535  -7.85686  1.000 23.90647 ? 425  TRP B NE1 1 
ATOM   6763 C  CE2 . TRP B  1 394 ? 0.83985  15.74973  -7.96173  1.000 23.41603 ? 425  TRP B CE2 1 
ATOM   6764 C  CE3 . TRP B  1 394 ? 2.84023  14.86094  -8.99245  1.000 21.60192 ? 425  TRP B CE3 1 
ATOM   6765 C  CZ2 . TRP B  1 394 ? 0.50057  14.50398  -7.44189  1.000 23.63068 ? 425  TRP B CZ2 1 
ATOM   6766 C  CZ3 . TRP B  1 394 ? 2.50327  13.62757  -8.47703  1.000 21.90310 ? 425  TRP B CZ3 1 
ATOM   6767 C  CH2 . TRP B  1 394 ? 1.33954  13.45678  -7.70905  1.000 25.53125 ? 425  TRP B CH2 1 
ATOM   6768 N  N   . LYS B  1 395 ? 6.30032  18.18412  -10.26899 1.000 18.19191 ? 426  LYS B N   1 
ATOM   6769 C  CA  . LYS B  1 395 ? 7.37855  18.58832  -11.15690 1.000 19.57749 ? 426  LYS B CA  1 
ATOM   6770 C  C   . LYS B  1 395 ? 7.65119  17.48566  -12.16184 1.000 18.73256 ? 426  LYS B C   1 
ATOM   6771 O  O   . LYS B  1 395 ? 7.66030  16.30307  -11.81329 1.000 17.65267 ? 426  LYS B O   1 
ATOM   6772 C  CB  . LYS B  1 395 ? 8.67020  18.87839  -10.39835 1.000 18.86464 ? 426  LYS B CB  1 
ATOM   6773 C  CG  . LYS B  1 395 ? 9.72586  19.53290  -11.29921 1.000 20.16677 ? 426  LYS B CG  1 
ATOM   6774 C  CD  . LYS B  1 395 ? 11.08800 19.43637  -10.68881 1.000 20.25184 ? 426  LYS B CD  1 
ATOM   6775 C  CE  . LYS B  1 395 ? 12.14902 19.96798  -11.65063 1.000 16.36144 ? 426  LYS B CE  1 
ATOM   6776 N  NZ  . LYS B  1 395 ? 13.46835 19.80268  -10.99087 1.000 17.18502 ? 426  LYS B NZ  1 
ATOM   6777 N  N   . ILE B  1 396 ? 7.89177  17.87699  -13.40777 1.000 18.47830 ? 427  ILE B N   1 
ATOM   6778 C  CA  . ILE B  1 396 ? 8.41735  16.96494  -14.41226 1.000 16.99378 ? 427  ILE B CA  1 
ATOM   6779 C  C   . ILE B  1 396 ? 9.86915  17.32758  -14.66340 1.000 14.96716 ? 427  ILE B C   1 
ATOM   6780 O  O   . ILE B  1 396 ? 10.24673 18.50510  -14.64319 1.000 16.85318 ? 427  ILE B O   1 
ATOM   6781 C  CB  . ILE B  1 396 ? 7.60243  16.98084  -15.71798 1.000 17.35349 ? 427  ILE B CB  1 
ATOM   6782 C  CG1 . ILE B  1 396 ? 7.53244  18.39166  -16.31814 1.000 18.71290 ? 427  ILE B CG1 1 
ATOM   6783 C  CG2 . ILE B  1 396 ? 6.20673  16.38968  -15.45217 1.000 18.99324 ? 427  ILE B CG2 1 
ATOM   6784 C  CD1 . ILE B  1 396 ? 6.95073  18.41233  -17.75346 1.000 20.81122 ? 427  ILE B CD1 1 
ATOM   6785 N  N   . THR B  1 397 ? 10.68676 16.30062  -14.87147 1.000 15.79612 ? 428  THR B N   1 
ATOM   6786 C  CA  . THR B  1 397 ? 12.11351 16.48166  -15.06622 1.000 15.54427 ? 428  THR B CA  1 
ATOM   6787 C  C   . THR B  1 397 ? 12.57761 15.56289  -16.17922 1.000 16.94034 ? 428  THR B C   1 
ATOM   6788 O  O   . THR B  1 397 ? 12.23039 14.37763  -16.19765 1.000 18.44340 ? 428  THR B O   1 
ATOM   6789 C  CB  . THR B  1 397 ? 12.88043 16.15367  -13.78721 1.000 18.50702 ? 428  THR B CB  1 
ATOM   6790 O  OG1 . THR B  1 397 ? 12.29869 16.86890  -12.69284 1.000 18.29186 ? 428  THR B OG1 1 
ATOM   6791 C  CG2 . THR B  1 397 ? 14.34316 16.55994  -13.92947 1.000 17.59094 ? 428  THR B CG2 1 
ATOM   6792 N  N   . ARG B  1 398 ? 13.37790 16.10213  -17.09060 1.000 16.65625 ? 429  ARG B N   1 
ATOM   6793 C  CA  . ARG B  1 398 ? 14.14679 15.26979  -18.00375 1.000 15.67053 ? 429  ARG B CA  1 
ATOM   6794 C  C   . ARG B  1 398 ? 15.60591 15.67908  -17.89196 1.000 16.17262 ? 429  ARG B C   1 
ATOM   6795 O  O   . ARG B  1 398 ? 15.94616 16.84822  -18.10216 1.000 17.20746 ? 429  ARG B O   1 
ATOM   6796 C  CB  . ARG B  1 398 ? 13.65344 15.38084  -19.45163 1.000 18.46554 ? 429  ARG B CB  1 
ATOM   6797 C  CG  . ARG B  1 398 ? 14.26635 14.26476  -20.29526 1.000 17.68500 ? 429  ARG B CG  1 
ATOM   6798 C  CD  . ARG B  1 398 ? 13.69165 14.17445  -21.71312 1.000 17.22349 ? 429  ARG B CD  1 
ATOM   6799 N  NE  . ARG B  1 398 ? 14.26357 13.03764  -22.43114 1.000 16.35517 ? 429  ARG B NE  1 
ATOM   6800 C  CZ  . ARG B  1 398 ? 14.09400 12.82736  -23.73064 1.000 17.33596 ? 429  ARG B CZ  1 
ATOM   6801 N  NH1 . ARG B  1 398 ? 13.39753 13.67425  -24.47799 1.000 19.21802 ? 429  ARG B NH1 1 
ATOM   6802 N  NH2 . ARG B  1 398 ? 14.62860 11.74268  -24.28647 1.000 16.29882 ? 429  ARG B NH2 1 
ATOM   6803 N  N   . MET B  1 399 ? 16.45496 14.72059  -17.52381 1.000 16.79131 ? 430  MET B N   1 
ATOM   6804 C  CA  . MET B  1 399 ? 17.88682 14.93815  -17.36411 1.000 15.36977 ? 430  MET B CA  1 
ATOM   6805 C  C   . MET B  1 399 ? 18.63548 13.88507  -18.17201 1.000 15.49500 ? 430  MET B C   1 
ATOM   6806 O  O   . MET B  1 399 ? 18.23863 12.72041  -18.20097 1.000 16.76304 ? 430  MET B O   1 
ATOM   6807 C  CB  . MET B  1 399 ? 18.29065 14.87444  -15.86691 1.000 14.50936 ? 430  MET B CB  1 
ATOM   6808 C  CG  . MET B  1 399 ? 18.12306 16.21685  -15.14056 1.000 15.07709 ? 430  MET B CG  1 
ATOM   6809 S  SD  . MET B  1 399 ? 19.29272 17.44871  -15.77748 1.000 16.81013 ? 430  MET B SD  1 
ATOM   6810 C  CE  . MET B  1 399 ? 20.84845 16.70148  -15.29420 1.000 17.27658 ? 430  MET B CE  1 
ATOM   6811 N  N   . GLY B  1 400 ? 19.71154 14.30636  -18.84095 1.000 16.45900 ? 431  GLY B N   1 
ATOM   6812 C  CA  . GLY B  1 400 ? 20.53503 13.38369  -19.60745 1.000 15.50260 ? 431  GLY B CA  1 
ATOM   6813 C  C   . GLY B  1 400 ? 19.85012 12.72861  -20.78692 1.000 16.79854 ? 431  GLY B C   1 
ATOM   6814 O  O   . GLY B  1 400 ? 20.36181 11.72896  -21.29883 1.000 16.27926 ? 431  GLY B O   1 
ATOM   6815 N  N   . ASN B  1 401 ? 18.71014 13.26089  -21.21870 1.000 17.62584 ? 432  ASN B N   1 
ATOM   6816 C  CA  . ASN B  1 401 ? 17.86932 12.69520  -22.27137 1.000 17.14952 ? 432  ASN B CA  1 
ATOM   6817 C  C   . ASN B  1 401 ? 17.27153 11.34815  -21.88111 1.000 17.15883 ? 432  ASN B C   1 
ATOM   6818 O  O   . ASN B  1 401 ? 16.83275 10.58859  -22.74999 1.000 16.57679 ? 432  ASN B O   1 
ATOM   6819 C  CB  . ASN B  1 401 ? 18.61811 12.57363  -23.61173 1.000 18.24944 ? 432  ASN B CB  1 
ATOM   6820 C  CG  . ASN B  1 401 ? 17.77429 13.06508  -24.78347 1.000 18.76676 ? 432  ASN B CG  1 
ATOM   6821 O  OD1 . ASN B  1 401 ? 16.94488 13.95011  -24.61555 1.000 19.45369 ? 432  ASN B OD1 1 
ATOM   6822 N  ND2 . ASN B  1 401 ? 17.96675 12.46820  -25.96792 1.000 20.56711 ? 432  ASN B ND2 1 
ATOM   6823 N  N   . GLU B  1 402 ? 17.22660 11.04914  -20.58646 1.000 17.94687 ? 433  GLU B N   1 
ATOM   6824 C  CA  . GLU B  1 402 ? 16.60943 9.84886   -20.05164 1.000 17.49067 ? 433  GLU B CA  1 
ATOM   6825 C  C   . GLU B  1 402 ? 15.08632 9.95738   -20.11441 1.000 17.42295 ? 433  GLU B C   1 
ATOM   6826 O  O   . GLU B  1 402 ? 14.54834 11.00970  -20.45131 1.000 18.18649 ? 433  GLU B O   1 
ATOM   6827 C  CB  . GLU B  1 402 ? 17.09661 9.63980   -18.61578 1.000 18.78569 ? 433  GLU B CB  1 
ATOM   6828 C  CG  . GLU B  1 402 ? 18.52075 9.13947   -18.57238 1.000 19.56888 ? 433  GLU B CG  1 
ATOM   6829 C  CD  . GLU B  1 402 ? 18.62308 7.71070   -19.07519 1.000 20.15954 ? 433  GLU B CD  1 
ATOM   6830 O  OE1 . GLU B  1 402 ? 17.98069 6.83447   -18.45960 1.000 21.39590 ? 433  GLU B OE1 1 
ATOM   6831 O  OE2 . GLU B  1 402 ? 19.32397 7.46459   -20.08461 1.000 20.96046 ? 433  GLU B OE2 1 
ATOM   6832 N  N   . PRO B  1 403 ? 14.35934 8.87484   -19.81577 1.000 17.81226 ? 434  PRO B N   1 
ATOM   6833 C  CA  . PRO B  1 403 ? 12.89134 8.96652   -19.79733 1.000 16.68255 ? 434  PRO B CA  1 
ATOM   6834 C  C   . PRO B  1 403 ? 12.40641 10.05380  -18.85103 1.000 18.50249 ? 434  PRO B C   1 
ATOM   6835 O  O   . PRO B  1 403 ? 13.03713 10.35994  -17.83356 1.000 19.19584 ? 434  PRO B O   1 
ATOM   6836 C  CB  . PRO B  1 403 ? 12.45396 7.57905   -19.31439 1.000 20.10344 ? 434  PRO B CB  1 
ATOM   6837 C  CG  . PRO B  1 403 ? 13.56199 6.67067   -19.78960 1.000 19.20721 ? 434  PRO B CG  1 
ATOM   6838 C  CD  . PRO B  1 403 ? 14.82288 7.48726   -19.61470 1.000 18.35075 ? 434  PRO B CD  1 
ATOM   6839 N  N   . TRP B  1 404 ? 11.26026 10.62791  -19.19945 1.000 17.75500 ? 435  TRP B N   1 
ATOM   6840 C  CA  . TRP B  1 404 ? 10.65200 11.67611  -18.39798 1.000 17.12047 ? 435  TRP B CA  1 
ATOM   6841 C  C   . TRP B  1 404 ? 10.30768 11.18228  -16.99831 1.000 19.78304 ? 435  TRP B C   1 
ATOM   6842 O  O   . TRP B  1 404 ? 9.88951  10.03565  -16.80412 1.000 19.05701 ? 435  TRP B O   1 
ATOM   6843 C  CB  . TRP B  1 404 ? 9.38391  12.18855  -19.08027 1.000 19.07365 ? 435  TRP B CB  1 
ATOM   6844 C  CG  . TRP B  1 404 ? 9.67403  13.21031  -20.12305 1.000 20.04188 ? 435  TRP B CG  1 
ATOM   6845 C  CD1 . TRP B  1 404 ? 9.79969  13.00641  -21.46849 1.000 20.06495 ? 435  TRP B CD1 1 
ATOM   6846 C  CD2 . TRP B  1 404 ? 9.88666  14.60318  -19.90246 1.000 18.54615 ? 435  TRP B CD2 1 
ATOM   6847 N  NE1 . TRP B  1 404 ? 10.08021 14.19650  -22.09753 1.000 18.16968 ? 435  TRP B NE1 1 
ATOM   6848 C  CE2 . TRP B  1 404 ? 10.13118 15.19325  -21.15502 1.000 19.30178 ? 435  TRP B CE2 1 
ATOM   6849 C  CE3 . TRP B  1 404 ? 9.88148  15.41437  -18.75874 1.000 18.19978 ? 435  TRP B CE3 1 
ATOM   6850 C  CZ2 . TRP B  1 404 ? 10.38115 16.55624  -21.30025 1.000 16.99539 ? 435  TRP B CZ2 1 
ATOM   6851 C  CZ3 . TRP B  1 404 ? 10.11844 16.76152  -18.90371 1.000 18.81641 ? 435  TRP B CZ3 1 
ATOM   6852 C  CH2 . TRP B  1 404 ? 10.37011 17.32523  -20.17087 1.000 19.06492 ? 435  TRP B CH2 1 
ATOM   6853 N  N   . ARG B  1 405 ? 10.46691 12.07311  -16.02741 1.000 18.67684 ? 436  ARG B N   1 
ATOM   6854 C  CA  . ARG B  1 405 ? 10.12748 11.79928  -14.63981 1.000 18.22417 ? 436  ARG B CA  1 
ATOM   6855 C  C   . ARG B  1 405 ? 9.02744  12.74041  -14.17141 1.000 16.46062 ? 436  ARG B C   1 
ATOM   6856 O  O   . ARG B  1 405 ? 9.00753  13.92138  -14.53027 1.000 18.54041 ? 436  ARG B O   1 
ATOM   6857 C  CB  . ARG B  1 405 ? 11.35755 11.96546  -13.73944 1.000 20.00647 ? 436  ARG B CB  1 
ATOM   6858 C  CG  . ARG B  1 405 ? 12.53049 11.12382  -14.15920 1.000 18.51047 ? 436  ARG B CG  1 
ATOM   6859 C  CD  . ARG B  1 405 ? 13.77996 11.54712  -13.39413 1.000 20.02662 ? 436  ARG B CD  1 
ATOM   6860 N  NE  . ARG B  1 405 ? 13.74460 11.11284  -12.00002 1.000 19.36573 ? 436  ARG B NE  1 
ATOM   6861 C  CZ  . ARG B  1 405 ? 14.08435 9.90270   -11.58067 1.000 20.80141 ? 436  ARG B CZ  1 
ATOM   6862 N  NH1 . ARG B  1 405 ? 14.42872 8.94798   -12.43222 1.000 24.73058 ? 436  ARG B NH1 1 
ATOM   6863 N  NH2 . ARG B  1 405 ? 14.07892 9.63910   -10.27323 1.000 20.08795 ? 436  ARG B NH2 1 
ATOM   6864 N  N   . LEU B  1 406 ? 8.11994  12.20693  -13.35867 1.000 17.47043 ? 437  LEU B N   1 
ATOM   6865 C  CA  . LEU B  1 406 ? 7.12265  12.99421  -12.64938 1.000 17.74774 ? 437  LEU B CA  1 
ATOM   6866 C  C   . LEU B  1 406 ? 7.36475  12.82337  -11.15747 1.000 17.37555 ? 437  LEU B C   1 
ATOM   6867 O  O   . LEU B  1 406 ? 7.46380  11.69501  -10.67161 1.000 17.41940 ? 437  LEU B O   1 
ATOM   6868 C  CB  . LEU B  1 406 ? 5.70013  12.54019  -13.00422 1.000 16.40701 ? 437  LEU B CB  1 
ATOM   6869 C  CG  . LEU B  1 406 ? 4.61492  13.27462  -12.21213 1.000 17.11110 ? 437  LEU B CG  1 
ATOM   6870 C  CD1 . LEU B  1 406 ? 4.49045  14.72277  -12.64177 1.000 18.93299 ? 437  LEU B CD1 1 
ATOM   6871 C  CD2 . LEU B  1 406 ? 3.28055  12.54573  -12.36229 1.000 19.36441 ? 437  LEU B CD2 1 
ATOM   6872 N  N   . HIS B  1 407 ? 7.47714  13.93298  -10.43533 1.000 17.73181 ? 438  HIS B N   1 
ATOM   6873 C  CA  . HIS B  1 407 ? 7.74189  13.88490  -9.00488  1.000 16.78123 ? 438  HIS B CA  1 
ATOM   6874 C  C   . HIS B  1 407 ? 6.70602  14.69798  -8.25359  1.000 17.08705 ? 438  HIS B C   1 
ATOM   6875 O  O   . HIS B  1 407 ? 6.31202  15.77959  -8.69740  1.000 17.34793 ? 438  HIS B O   1 
ATOM   6876 C  CB  . HIS B  1 407 ? 9.13925  14.42623  -8.68156  1.000 18.48285 ? 438  HIS B CB  1 
ATOM   6877 C  CG  . HIS B  1 407 ? 10.23844 13.57418  -9.22818  1.000 17.95813 ? 438  HIS B CG  1 
ATOM   6878 N  ND1 . HIS B  1 407 ? 10.49268 12.30462  -8.75395  1.000 20.43687 ? 438  HIS B ND1 1 
ATOM   6879 C  CD2 . HIS B  1 407 ? 11.12771 13.79126  -10.22633 1.000 19.14944 ? 438  HIS B CD2 1 
ATOM   6880 C  CE1 . HIS B  1 407 ? 11.49873 11.77695  -9.43045  1.000 19.46257 ? 438  HIS B CE1 1 
ATOM   6881 N  NE2 . HIS B  1 407 ? 11.90053 12.65750  -10.33031 1.000 16.29397 ? 438  HIS B NE2 1 
ATOM   6882 N  N   . ASN B  1 408 ? 6.26999  14.18119  -7.10468  1.000 17.27110 ? 439  ASN B N   1 
ATOM   6883 C  CA  . ASN B  1 408 ? 5.59810  15.05845  -6.15491  1.000 17.73867 ? 439  ASN B CA  1 
ATOM   6884 C  C   . ASN B  1 408 ? 6.71519  15.72737  -5.37268  1.000 18.48034 ? 439  ASN B C   1 
ATOM   6885 O  O   . ASN B  1 408 ? 7.29672  15.13181  -4.46329  1.000 18.60966 ? 439  ASN B O   1 
ATOM   6886 C  CB  . ASN B  1 408 ? 4.63830  14.29281  -5.25182  1.000 19.05242 ? 439  ASN B CB  1 
ATOM   6887 C  CG  . ASN B  1 408 ? 3.83891  15.22766  -4.34882  1.000 22.19036 ? 439  ASN B CG  1 
ATOM   6888 O  OD1 . ASN B  1 408 ? 4.40046  16.07277  -3.65056  1.000 21.76108 ? 439  ASN B OD1 1 
ATOM   6889 N  ND2 . ASN B  1 408 ? 2.51327  15.10850  -4.39891  1.000 24.78437 ? 439  ASN B ND2 1 
ATOM   6890 N  N   . ILE B  1 409 ? 7.05929  16.95213  -5.77575  1.000 16.59346 ? 440  ILE B N   1 
ATOM   6891 C  CA  . ILE B  1 409 ? 8.26379  17.58518  -5.25438  1.000 17.49718 ? 440  ILE B CA  1 
ATOM   6892 C  C   . ILE B  1 409 ? 8.07990  17.99910  -3.80759  1.000 17.81805 ? 440  ILE B C   1 
ATOM   6893 O  O   . ILE B  1 409 ? 9.06523  18.16721  -3.07831  1.000 19.37086 ? 440  ILE B O   1 
ATOM   6894 C  CB  . ILE B  1 409 ? 8.65475  18.77188  -6.16098  1.000 17.61578 ? 440  ILE B CB  1 
ATOM   6895 C  CG1 . ILE B  1 409 ? 10.13636 19.13112  -5.98157  1.000 18.35866 ? 440  ILE B CG1 1 
ATOM   6896 C  CG2 . ILE B  1 409 ? 7.76061  19.99634  -5.90853  1.000 18.36836 ? 440  ILE B CG2 1 
ATOM   6897 C  CD1 . ILE B  1 409 ? 11.08033 18.04208  -6.50021  1.000 17.39957 ? 440  ILE B CD1 1 
ATOM   6898 N  N   . THR B  1 410 ? 6.83499  18.13138  -3.35352  1.000 18.40936 ? 441  THR B N   1 
ATOM   6899 C  CA  . THR B  1 410 ? 6.60117  18.42184  -1.94491  1.000 19.41960 ? 441  THR B CA  1 
ATOM   6900 C  C   . THR B  1 410 ? 6.87283  17.20294  -1.06695  1.000 20.41207 ? 441  THR B C   1 
ATOM   6901 O  O   . THR B  1 410 ? 7.43669  17.33380  0.02904   1.000 21.27692 ? 441  THR B O   1 
ATOM   6902 C  CB  . THR B  1 410 ? 5.16909  18.92456  -1.76438  1.000 18.96356 ? 441  THR B CB  1 
ATOM   6903 O  OG1 . THR B  1 410 ? 4.99261  20.10651  -2.54407  1.000 19.03180 ? 441  THR B OG1 1 
ATOM   6904 C  CG2 . THR B  1 410 ? 4.87532  19.23458  -0.29691  1.000 21.78891 ? 441  THR B CG2 1 
ATOM   6905 N  N   . GLN B  1 411 ? 6.47979  16.01211  -1.52303  1.000 18.72467 ? 442  GLN B N   1 
ATOM   6906 C  CA  . GLN B  1 411 ? 6.71863  14.78774  -0.77062  1.000 18.85714 ? 442  GLN B CA  1 
ATOM   6907 C  C   . GLN B  1 411 ? 8.06531  14.14890  -1.07699  1.000 20.99144 ? 442  GLN B C   1 
ATOM   6908 O  O   . GLN B  1 411 ? 8.53317  13.31907  -0.29009  1.000 22.71497 ? 442  GLN B O   1 
ATOM   6909 C  CB  . GLN B  1 411 ? 5.59600  13.77970  -1.04861  1.000 22.13833 ? 442  GLN B CB  1 
ATOM   6910 C  CG  . GLN B  1 411 ? 4.22460  14.32463  -0.65958  1.000 23.27252 ? 442  GLN B CG  1 
ATOM   6911 C  CD  . GLN B  1 411 ? 3.08577  13.38132  -1.01271  1.000 38.87330 ? 442  GLN B CD  1 
ATOM   6912 O  OE1 . GLN B  1 411 ? 3.30565  12.29110  -1.53526  1.000 43.63041 ? 442  GLN B OE1 1 
ATOM   6913 N  NE2 . GLN B  1 411 ? 1.86151  13.80014  -0.72438  1.000 43.80125 ? 442  GLN B NE2 1 
ATOM   6914 N  N   . ASP B  1 412 ? 8.71326  14.53684  -2.19101  1.000 19.27415 ? 443  ASP B N   1 
ATOM   6915 C  CA  . ASP B  1 412 ? 9.89417  13.84945  -2.73050  1.000 16.49537 ? 443  ASP B CA  1 
ATOM   6916 C  C   . ASP B  1 412 ? 10.84133 14.93252  -3.25741  1.000 17.01503 ? 443  ASP B C   1 
ATOM   6917 O  O   . ASP B  1 412 ? 11.09717 15.03615  -4.45923  1.000 16.58246 ? 443  ASP B O   1 
ATOM   6918 C  CB  . ASP B  1 412 ? 9.46820  12.86356  -3.82549  1.000 16.91900 ? 443  ASP B CB  1 
ATOM   6919 C  CG  . ASP B  1 412 ? 10.63079 12.14453  -4.52180  1.000 18.23979 ? 443  ASP B CG  1 
ATOM   6920 O  OD1 . ASP B  1 412 ? 11.75963 12.01151  -3.98484  1.000 18.60032 ? 443  ASP B OD1 1 
ATOM   6921 O  OD2 . ASP B  1 412 ? 10.37514 11.69082  -5.65410  1.000 18.89394 ? 443  ASP B OD2 1 
ATOM   6922 N  N   . ILE B  1 413 ? 11.36111 15.75626  -2.33648  1.000 17.77996 ? 444  ILE B N   1 
ATOM   6923 C  CA  . ILE B  1 413 ? 12.14028 16.93108  -2.73352  1.000 17.80714 ? 444  ILE B CA  1 
ATOM   6924 C  C   . ILE B  1 413 ? 13.43125 16.51967  -3.43867  1.000 16.15766 ? 444  ILE B C   1 
ATOM   6925 O  O   . ILE B  1 413 ? 13.97688 17.28518  -4.24237  1.000 17.74691 ? 444  ILE B O   1 
ATOM   6926 C  CB  . ILE B  1 413 ? 12.41572 17.82127  -1.50651  1.000 16.65069 ? 444  ILE B CB  1 
ATOM   6927 C  CG1 . ILE B  1 413 ? 12.87382 19.22136  -1.93567  1.000 16.87122 ? 444  ILE B CG1 1 
ATOM   6928 C  CG2 . ILE B  1 413 ? 13.43139 17.16629  -0.55422  1.000 17.49162 ? 444  ILE B CG2 1 
ATOM   6929 C  CD1 . ILE B  1 413 ? 13.02281 20.20291  -0.75980  1.000 18.83134 ? 444  ILE B CD1 1 
ATOM   6930 N  N   . GLY B  1 414 ? 13.92951 15.31939  -3.16257  1.000 17.59205 ? 445  GLY B N   1 
ATOM   6931 C  CA  . GLY B  1 414 ? 15.13745 14.79448  -3.77523  1.000 17.12975 ? 445  GLY B CA  1 
ATOM   6932 C  C   . GLY B  1 414 ? 14.95849 14.15504  -5.12518  1.000 17.06888 ? 445  GLY B C   1 
ATOM   6933 O  O   . GLY B  1 414 ? 15.92877 13.62840  -5.67648  1.000 17.24958 ? 445  GLY B O   1 
ATOM   6934 N  N   . GLU B  1 415 ? 13.74054 14.16228  -5.66525  1.000 16.20693 ? 446  GLU B N   1 
ATOM   6935 C  CA  . GLU B  1 415 ? 13.45019 13.63003  -7.00656  1.000 14.87391 ? 446  GLU B CA  1 
ATOM   6936 C  C   . GLU B  1 415 ? 13.91316 12.17287  -7.15664  1.000 15.91920 ? 446  GLU B C   1 
ATOM   6937 O  O   . GLU B  1 415 ? 14.53363 11.77422  -8.14784  1.000 16.50260 ? 446  GLU B O   1 
ATOM   6938 C  CB  . GLU B  1 415 ? 14.06401 14.52908  -8.08632  1.000 15.55849 ? 446  GLU B CB  1 
ATOM   6939 C  CG  . GLU B  1 415 ? 13.33588 15.86157  -8.23792  1.000 16.47430 ? 446  GLU B CG  1 
ATOM   6940 C  CD  . GLU B  1 415 ? 14.09396 16.85382  -9.09355  1.000 16.17450 ? 446  GLU B CD  1 
ATOM   6941 O  OE1 . GLU B  1 415 ? 15.16177 17.32368  -8.65125  1.000 15.95399 ? 446  GLU B OE1 1 
ATOM   6942 O  OE2 . GLU B  1 415 ? 13.61191 17.15950  -10.20307 1.000 18.40835 ? 446  GLU B OE2 1 
ATOM   6943 N  N   . LYS B  1 416 ? 13.56619 11.35423  -6.16683  1.000 16.57418 ? 447  LYS B N   1 
ATOM   6944 C  CA  . LYS B  1 416 ? 13.98524 9.95716   -6.13958  1.000 15.22585 ? 447  LYS B CA  1 
ATOM   6945 C  C   . LYS B  1 416 ? 12.95718 8.99259   -6.71071  1.000 18.25556 ? 447  LYS B C   1 
ATOM   6946 O  O   . LYS B  1 416 ? 13.33929 7.91653   -7.18957  1.000 19.26039 ? 447  LYS B O   1 
ATOM   6947 C  CB  . LYS B  1 416 ? 14.30111 9.53464   -4.70305  1.000 16.97710 ? 447  LYS B CB  1 
ATOM   6948 C  CG  . LYS B  1 416 ? 15.47247 10.28494  -4.09033  1.000 19.92617 ? 447  LYS B CG  1 
ATOM   6949 C  CD  . LYS B  1 416 ? 15.81432 9.71235   -2.71900  1.000 21.32658 ? 447  LYS B CD  1 
ATOM   6950 C  CE  . LYS B  1 416 ? 17.07072 10.35457  -2.16077  1.000 31.78111 ? 447  LYS B CE  1 
ATOM   6951 N  NZ  . LYS B  1 416 ? 17.35142 9.88509   -0.77321  1.000 39.53765 ? 447  LYS B NZ  1 
ATOM   6952 N  N   . LYS B  1 417 ? 11.66692 9.33685   -6.66216  1.000 18.05228 ? 448  LYS B N   1 
ATOM   6953 C  CA  . LYS B  1 417 ? 10.58663 8.39407   -6.95925  1.000 18.90693 ? 448  LYS B CA  1 
ATOM   6954 C  C   . LYS B  1 417 ? 9.81295  8.88016   -8.17885  1.000 16.43961 ? 448  LYS B C   1 
ATOM   6955 O  O   . LYS B  1 417 ? 9.00431  9.80885   -8.08355  1.000 19.20317 ? 448  LYS B O   1 
ATOM   6956 C  CB  . LYS B  1 417 ? 9.66113  8.23675   -5.75824  1.000 21.02542 ? 448  LYS B CB  1 
ATOM   6957 C  CG  . LYS B  1 417 ? 10.38085 7.94274   -4.45504  1.000 23.44560 ? 448  LYS B CG  1 
ATOM   6958 C  CD  . LYS B  1 417 ? 11.23166 6.70176   -4.56561  1.000 24.67676 ? 448  LYS B CD  1 
ATOM   6959 C  CE  . LYS B  1 417 ? 12.04125 6.52388   -3.29173  1.000 29.05111 ? 448  LYS B CE  1 
ATOM   6960 N  NZ  . LYS B  1 417 ? 12.80138 5.25455   -3.27672  1.000 33.79329 ? 448  LYS B NZ  1 
ATOM   6961 N  N   . ASN B  1 418 ? 10.04186 8.23178   -9.31287  1.000 17.73773 ? 449  ASN B N   1 
ATOM   6962 C  CA  . ASN B  1 418 ? 9.36147  8.58608   -10.55056 1.000 18.81506 ? 449  ASN B CA  1 
ATOM   6963 C  C   . ASN B  1 418 ? 7.93208  8.06010   -10.50784 1.000 20.88783 ? 449  ASN B C   1 
ATOM   6964 O  O   . ASN B  1 418 ? 7.70934  6.84754   -10.39300 1.000 21.90928 ? 449  ASN B O   1 
ATOM   6965 C  CB  . ASN B  1 418 ? 10.11713 8.01121   -11.74849 1.000 18.51788 ? 449  ASN B CB  1 
ATOM   6966 C  CG  . ASN B  1 418 ? 9.59721  8.52813   -13.08052 1.000 20.19695 ? 449  ASN B CG  1 
ATOM   6967 O  OD1 . ASN B  1 418 ? 8.63963  9.30175   -13.13865 1.000 19.24369 ? 449  ASN B OD1 1 
ATOM   6968 N  ND2 . ASN B  1 418 ? 10.24162 8.10680   -14.16065 1.000 22.99738 ? 449  ASN B ND2 1 
ATOM   6969 N  N   . LEU B  1 419 ? 6.96903  8.97573   -10.58278 1.000 19.73211 ? 450  LEU B N   1 
ATOM   6970 C  CA  . LEU B  1 419 ? 5.55372  8.64770   -10.57779 1.000 19.84739 ? 450  LEU B CA  1 
ATOM   6971 C  C   . LEU B  1 419 ? 4.93888  8.70584   -11.97287 1.000 20.90016 ? 450  LEU B C   1 
ATOM   6972 O  O   . LEU B  1 419 ? 3.71106  8.72952   -12.09315 1.000 23.88270 ? 450  LEU B O   1 
ATOM   6973 C  CB  . LEU B  1 419 ? 4.81281  9.59491   -9.62914  1.000 20.37703 ? 450  LEU B CB  1 
ATOM   6974 C  CG  . LEU B  1 419 ? 5.32346  9.57212   -8.18526  1.000 21.66443 ? 450  LEU B CG  1 
ATOM   6975 C  CD1 . LEU B  1 419 ? 4.62203  10.62487  -7.35543  1.000 21.46621 ? 450  LEU B CD1 1 
ATOM   6976 C  CD2 . LEU B  1 419 ? 5.15005  8.18697   -7.57460  1.000 27.61650 ? 450  LEU B CD2 1 
ATOM   6977 N  N   . ALA B  1 420 ? 5.76419  8.72773   -13.02319 1.000 20.45531 ? 451  ALA B N   1 
ATOM   6978 C  CA  . ALA B  1 420 ? 5.25251  8.86088   -14.38603 1.000 22.08362 ? 451  ALA B CA  1 
ATOM   6979 C  C   . ALA B  1 420 ? 4.29239  7.73277   -14.73560 1.000 27.81770 ? 451  ALA B C   1 
ATOM   6980 O  O   . ALA B  1 420 ? 3.31527  7.94360   -15.46676 1.000 28.21280 ? 451  ALA B O   1 
ATOM   6981 C  CB  . ALA B  1 420 ? 6.41644  8.89545   -15.38121 1.000 21.52465 ? 451  ALA B CB  1 
ATOM   6982 N  N   . GLY B  1 421 ? 4.55696  6.52632   -14.22683 1.000 24.49398 ? 452  GLY B N   1 
ATOM   6983 C  CA  . GLY B  1 421 ? 3.66752  5.40811   -14.48791 1.000 26.40929 ? 452  GLY B CA  1 
ATOM   6984 C  C   . GLY B  1 421 ? 2.39635  5.45284   -13.67531 1.000 27.42846 ? 452  GLY B C   1 
ATOM   6985 O  O   . GLY B  1 421 ? 1.37495  4.89905   -14.09152 1.000 29.90818 ? 452  GLY B O   1 
ATOM   6986 N  N   . ARG B  1 422 ? 2.43433  6.10482   -12.51283 1.000 26.20525 ? 453  ARG B N   1 
ATOM   6987 C  CA  . ARG B  1 422 ? 1.26212  6.17222   -11.65113 1.000 25.17787 ? 453  ARG B CA  1 
ATOM   6988 C  C   . ARG B  1 422 ? 0.28345  7.24772   -12.11151 1.000 29.30855 ? 453  ARG B C   1 
ATOM   6989 O  O   . ARG B  1 422 ? -0.93521 7.06123   -12.00903 1.000 28.71987 ? 453  ARG B O   1 
ATOM   6990 C  CB  . ARG B  1 422 ? 1.70534  6.40809   -10.20634 1.000 25.62104 ? 453  ARG B CB  1 
ATOM   6991 C  CG  . ARG B  1 422 ? 0.57173  6.59771   -9.20184  1.000 34.92811 ? 453  ARG B CG  1 
ATOM   6992 C  CD  . ARG B  1 422 ? -0.23815 5.32900   -8.98026  1.000 43.33852 ? 453  ARG B CD  1 
ATOM   6993 N  NE  . ARG B  1 422 ? -1.32267 5.55674   -8.03015  1.000 46.75619 ? 453  ARG B NE  1 
ATOM   6994 C  CZ  . ARG B  1 422 ? -2.50010 6.07950   -8.35011  1.000 48.05306 ? 453  ARG B CZ  1 
ATOM   6995 N  NH1 . ARG B  1 422 ? -2.79616 6.40369   -9.59912  1.000 43.80718 ? 453  ARG B NH1 1 
ATOM   6996 N  NH2 . ARG B  1 422 ? -3.39979 6.29030   -7.39238  1.000 45.93629 ? 453  ARG B NH2 1 
ATOM   6997 N  N   . TYR B  1 423 ? 0.78609  8.36860   -12.63281 1.000 25.95956 ? 454  TYR B N   1 
ATOM   6998 C  CA  . TYR B  1 423 ? -0.05169 9.48613   -13.07268 1.000 22.10460 ? 454  TYR B CA  1 
ATOM   6999 C  C   . TYR B  1 423 ? 0.33096  9.88989   -14.49501 1.000 24.73376 ? 454  TYR B C   1 
ATOM   7000 O  O   . TYR B  1 423 ? 0.81801  11.00235  -14.73014 1.000 23.57625 ? 454  TYR B O   1 
ATOM   7001 C  CB  . TYR B  1 423 ? 0.07240  10.67498  -12.11347 1.000 23.97156 ? 454  TYR B CB  1 
ATOM   7002 C  CG  . TYR B  1 423 ? -0.20959 10.35760  -10.65600 1.000 29.68466 ? 454  TYR B CG  1 
ATOM   7003 C  CD1 . TYR B  1 423 ? -1.51668 10.24903  -10.18363 1.000 33.42149 ? 454  TYR B CD1 1 
ATOM   7004 C  CD2 . TYR B  1 423 ? 0.82943  10.18604  -9.74946  1.000 30.35871 ? 454  TYR B CD2 1 
ATOM   7005 C  CE1 . TYR B  1 423 ? -1.77702 9.96144   -8.84898  1.000 33.96893 ? 454  TYR B CE1 1 
ATOM   7006 C  CE2 . TYR B  1 423 ? 0.57995  9.90508   -8.41351  1.000 30.63954 ? 454  TYR B CE2 1 
ATOM   7007 C  CZ  . TYR B  1 423 ? -0.72252 9.79515   -7.96977  1.000 37.76526 ? 454  TYR B CZ  1 
ATOM   7008 O  OH  . TYR B  1 423 ? -0.96125 9.51194   -6.64199  1.000 34.16930 ? 454  TYR B OH  1 
ATOM   7009 N  N   . PRO B  1 424 ? 0.09461  9.01582   -15.47773 1.000 24.85179 ? 455  PRO B N   1 
ATOM   7010 C  CA  . PRO B  1 424 ? 0.53655  9.33387   -16.84862 1.000 23.70131 ? 455  PRO B CA  1 
ATOM   7011 C  C   . PRO B  1 424 ? -0.16808 10.53705  -17.45423 1.000 24.74703 ? 455  PRO B C   1 
ATOM   7012 O  O   . PRO B  1 424 ? 0.45683  11.29882  -18.20364 1.000 22.62552 ? 455  PRO B O   1 
ATOM   7013 C  CB  . PRO B  1 424 ? 0.22186  8.04324   -17.62009 1.000 30.33601 ? 455  PRO B CB  1 
ATOM   7014 C  CG  . PRO B  1 424 ? -0.89133 7.41827   -16.84733 1.000 29.26324 ? 455  PRO B CG  1 
ATOM   7015 C  CD  . PRO B  1 424 ? -0.58442 7.70861   -15.41097 1.000 28.18200 ? 455  PRO B CD  1 
ATOM   7016 N  N   . ASP B  1 425 ? -1.45566 10.73184  -17.15852 1.000 25.50555 ? 456  ASP B N   1 
ATOM   7017 C  CA  . ASP B  1 425 ? -2.16838 11.87837  -17.71763 1.000 25.26403 ? 456  ASP B CA  1 
ATOM   7018 C  C   . ASP B  1 425 ? -1.60878 13.19224  -17.18825 1.000 24.14390 ? 456  ASP B C   1 
ATOM   7019 O  O   . ASP B  1 425 ? -1.50348 14.17229  -17.93550 1.000 24.70910 ? 456  ASP B O   1 
ATOM   7020 C  CB  . ASP B  1 425 ? -3.66025 11.78327  -17.41077 1.000 27.76271 ? 456  ASP B CB  1 
ATOM   7021 C  CG  . ASP B  1 425 ? -4.31766 10.59865  -18.08105 1.000 35.77210 ? 456  ASP B CG  1 
ATOM   7022 O  OD1 . ASP B  1 425 ? -3.76539 10.09060  -19.07819 1.000 36.59542 ? 456  ASP B OD1 1 
ATOM   7023 O  OD2 . ASP B  1 425 ? -5.39270 10.18135  -17.61269 1.000 39.16310 ? 456  ASP B OD2 1 
ATOM   7024 N  N   . ARG B  1 426 ? -1.24855 13.23338  -15.90191 1.000 25.45094 ? 457  ARG B N   1 
ATOM   7025 C  CA  . ARG B  1 426 ? -0.64828 14.44264  -15.34880 1.000 22.03330 ? 457  ARG B CA  1 
ATOM   7026 C  C   . ARG B  1 426 ? 0.71061  14.71679  -15.98499 1.000 22.42214 ? 457  ARG B C   1 
ATOM   7027 O  O   . ARG B  1 426 ? 1.01411  15.85929  -16.34572 1.000 21.91077 ? 457  ARG B O   1 
ATOM   7028 C  CB  . ARG B  1 426 ? -0.52020 14.32262  -13.82853 1.000 23.54072 ? 457  ARG B CB  1 
ATOM   7029 C  CG  . ARG B  1 426 ? 0.08328  15.55111  -13.15767 1.000 22.30914 ? 457  ARG B CG  1 
ATOM   7030 C  CD  . ARG B  1 426 ? 0.06867  15.45727  -11.61733 1.000 24.95338 ? 457  ARG B CD  1 
ATOM   7031 N  NE  . ARG B  1 426 ? -1.27486 15.31910  -11.05771 1.000 26.99884 ? 457  ARG B NE  1 
ATOM   7032 C  CZ  . ARG B  1 426 ? -2.04701 16.33246  -10.69139 1.000 25.19440 ? 457  ARG B CZ  1 
ATOM   7033 N  NH1 . ARG B  1 426 ? -1.65392 17.58774  -10.83412 1.000 25.26586 ? 457  ARG B NH1 1 
ATOM   7034 N  NH2 . ARG B  1 426 ? -3.25051 16.07916  -10.17066 1.000 27.41149 ? 457  ARG B NH2 1 
ATOM   7035 N  N   . LEU B  1 427 ? 1.53206  13.67813  -16.14447 1.000 22.42230 ? 458  LEU B N   1 
ATOM   7036 C  CA  . LEU B  1 427 ? 2.80362  13.83969  -16.84545 1.000 20.33636 ? 458  LEU B CA  1 
ATOM   7037 C  C   . LEU B  1 427 ? 2.59502  14.44987  -18.22673 1.000 23.09311 ? 458  LEU B C   1 
ATOM   7038 O  O   . LEU B  1 427 ? 3.27130  15.41187  -18.60397 1.000 22.07373 ? 458  LEU B O   1 
ATOM   7039 C  CB  . LEU B  1 427 ? 3.50941  12.48902  -16.96008 1.000 23.17364 ? 458  LEU B CB  1 
ATOM   7040 C  CG  . LEU B  1 427 ? 4.76300  12.44083  -17.84256 1.000 25.93117 ? 458  LEU B CG  1 
ATOM   7041 C  CD1 . LEU B  1 427 ? 5.90603  13.16434  -17.14410 1.000 31.46035 ? 458  LEU B CD1 1 
ATOM   7042 C  CD2 . LEU B  1 427 ? 5.16550  11.00575  -18.16122 1.000 31.05107 ? 458  LEU B CD2 1 
ATOM   7043 N  N   . LYS B  1 428 ? 1.64543  13.91028  -18.99221 1.000 24.12161 ? 459  LYS B N   1 
ATOM   7044 C  CA  . LYS B  1 428 ? 1.49013  14.36955  -20.36907 1.000 23.19830 ? 459  LYS B CA  1 
ATOM   7045 C  C   . LYS B  1 428 ? 0.85925  15.75448  -20.44278 1.000 22.62081 ? 459  LYS B C   1 
ATOM   7046 O  O   . LYS B  1 428 ? 1.17178  16.52178  -21.36123 1.000 22.43528 ? 459  LYS B O   1 
ATOM   7047 C  CB  . LYS B  1 428 ? 0.68782  13.34790  -21.16479 1.000 24.50674 ? 459  LYS B CB  1 
ATOM   7048 C  CG  . LYS B  1 428 ? 1.44146  12.03659  -21.27479 1.000 30.45403 ? 459  LYS B CG  1 
ATOM   7049 C  CD  . LYS B  1 428 ? 0.91879  11.13993  -22.36650 1.000 34.97472 ? 459  LYS B CD  1 
ATOM   7050 C  CE  . LYS B  1 428 ? 1.93213  10.03321  -22.66142 1.000 34.02603 ? 459  LYS B CE  1 
ATOM   7051 N  NZ  . LYS B  1 428 ? 1.37142  9.00739   -23.57877 1.000 37.69735 ? 459  LYS B NZ  1 
ATOM   7052 N  N   . GLU B  1 429 ? -0.00681 16.10306  -19.48483 1.000 24.18057 ? 460  GLU B N   1 
ATOM   7053 C  CA  . GLU B  1 429 ? -0.52903 17.46682  -19.42740 1.000 25.05586 ? 460  GLU B CA  1 
ATOM   7054 C  C   . GLU B  1 429 ? 0.58154  18.47170  -19.15359 1.000 23.86203 ? 460  GLU B C   1 
ATOM   7055 O  O   . GLU B  1 429 ? 0.63287  19.54174  -19.77280 1.000 23.95842 ? 460  GLU B O   1 
ATOM   7056 C  CB  . GLU B  1 429 ? -1.60609 17.58016  -18.34999 1.000 25.67741 ? 460  GLU B CB  1 
ATOM   7057 C  CG  . GLU B  1 429 ? -2.90728 16.88330  -18.69123 1.000 33.65000 ? 460  GLU B CG  1 
ATOM   7058 C  CD  . GLU B  1 429 ? -3.95050 17.06162  -17.59896 1.000 51.25027 ? 460  GLU B CD  1 
ATOM   7059 O  OE1 . GLU B  1 429 ? -3.57936 16.99395  -16.40200 1.000 51.73264 ? 460  GLU B OE1 1 
ATOM   7060 O  OE2 . GLU B  1 429 ? -5.13527 17.28417  -17.93505 1.000 60.73891 ? 460  GLU B OE2 1 
ATOM   7061 N  N   . MET B  1 430 ? 1.47598  18.14793  -18.21602 1.000 21.04753 ? 461  MET B N   1 
ATOM   7062 C  CA  . MET B  1 430 ? 2.56331  19.06156  -17.90427 1.000 21.33993 ? 461  MET B CA  1 
ATOM   7063 C  C   . MET B  1 430 ? 3.55219  19.14888  -19.05771 1.000 19.06647 ? 461  MET B C   1 
ATOM   7064 O  O   . MET B  1 430 ? 4.07317  20.22977  -19.34708 1.000 21.19945 ? 461  MET B O   1 
ATOM   7065 C  CB  . MET B  1 430 ? 3.25541  18.62042  -16.61738 1.000 21.99671 ? 461  MET B CB  1 
ATOM   7066 C  CG  . MET B  1 430 ? 2.31637  18.70573  -15.42040 1.000 21.47163 ? 461  MET B CG  1 
ATOM   7067 S  SD  . MET B  1 430 ? 3.11123  18.28197  -13.85838 1.000 21.96811 ? 461  MET B SD  1 
ATOM   7068 C  CE  . MET B  1 430 ? 4.26161  19.64595  -13.63833 1.000 22.26956 ? 461  MET B CE  1 
ATOM   7069 N  N   . ILE B  1 431 ? 3.79740  18.02803  -19.74049 1.000 20.46676 ? 462  ILE B N   1 
ATOM   7070 C  CA  . ILE B  1 431 ? 4.67865  18.04862  -20.90463 1.000 23.49891 ? 462  ILE B CA  1 
ATOM   7071 C  C   . ILE B  1 431 ? 4.07799  18.90422  -22.01280 1.000 24.35565 ? 462  ILE B C   1 
ATOM   7072 O  O   . ILE B  1 431 ? 4.78093  19.69953  -22.65206 1.000 23.22893 ? 462  ILE B O   1 
ATOM   7073 C  CB  . ILE B  1 431 ? 4.97122  16.61387  -21.37574 1.000 24.93083 ? 462  ILE B CB  1 
ATOM   7074 C  CG1 . ILE B  1 431 ? 6.00945  15.98109  -20.43942 1.000 26.54289 ? 462  ILE B CG1 1 
ATOM   7075 C  CG2 . ILE B  1 431 ? 5.43506  16.60722  -22.83202 1.000 27.34274 ? 462  ILE B CG2 1 
ATOM   7076 C  CD1 . ILE B  1 431 ? 6.06834  14.48775  -20.48982 1.000 31.02353 ? 462  ILE B CD1 1 
ATOM   7077 N  N   . ALA B  1 432 ? 2.76428  18.78311  -22.23490 1.000 23.06650 ? 463  ALA B N   1 
ATOM   7078 C  CA  . ALA B  1 432 ? 2.11265  19.57426  -23.27821 1.000 24.98707 ? 463  ALA B CA  1 
ATOM   7079 C  C   . ALA B  1 432 ? 2.24677  21.06804  -23.01345 1.000 22.84309 ? 463  ALA B C   1 
ATOM   7080 O  O   . ALA B  1 432 ? 2.54569  21.84881  -23.92802 1.000 24.49955 ? 463  ALA B O   1 
ATOM   7081 C  CB  . ALA B  1 432 ? 0.63890  19.18245  -23.38611 1.000 25.81657 ? 463  ALA B CB  1 
ATOM   7082 N  N   . LYS B  1 433 ? 2.01698  21.49071  -21.76851 1.000 21.13342 ? 464  LYS B N   1 
ATOM   7083 C  CA  . LYS B  1 433 ? 2.16984  22.89940  -21.42396 1.000 22.03712 ? 464  LYS B CA  1 
ATOM   7084 C  C   . LYS B  1 433 ? 3.61132  23.36297  -21.61398 1.000 21.60617 ? 464  LYS B C   1 
ATOM   7085 O  O   . LYS B  1 433 ? 3.85155  24.46568  -22.11311 1.000 23.62694 ? 464  LYS B O   1 
ATOM   7086 C  CB  . LYS B  1 433 ? 1.70415  23.13766  -19.98423 1.000 25.56319 ? 464  LYS B CB  1 
ATOM   7087 N  N   . THR B  1 434 ? 4.58418  22.52639  -21.23341 1.000 21.50872 ? 465  THR B N   1 
ATOM   7088 C  CA  . THR B  1 434 ? 5.98849  22.90361  -21.37341 1.000 20.96462 ? 465  THR B CA  1 
ATOM   7089 C  C   . THR B  1 434 ? 6.39546  22.98865  -22.83604 1.000 20.35352 ? 465  THR B C   1 
ATOM   7090 O  O   . THR B  1 434 ? 7.16251  23.88211  -23.22511 1.000 21.33526 ? 465  THR B O   1 
ATOM   7091 C  CB  . THR B  1 434 ? 6.87068  21.89856  -20.63510 1.000 21.70590 ? 465  THR B CB  1 
ATOM   7092 O  OG1 . THR B  1 434 ? 6.40333  21.78215  -19.29165 1.000 21.12881 ? 465  THR B OG1 1 
ATOM   7093 C  CG2 . THR B  1 434 ? 8.32856  22.36264  -20.62262 1.000 20.52004 ? 465  THR B CG2 1 
ATOM   7094 N  N   . GLN B  1 435 ? 5.89335  22.06805  -23.65874 1.000 20.03932 ? 466  GLN B N   1 
ATOM   7095 C  CA  . GLN B  1 435 ? 6.17745  22.13692  -25.08570 1.000 22.98940 ? 466  GLN B CA  1 
ATOM   7096 C  C   . GLN B  1 435 ? 5.61910  23.41841  -25.69055 1.000 23.39184 ? 466  GLN B C   1 
ATOM   7097 O  O   . GLN B  1 435 ? 6.27002  24.05899  -26.52704 1.000 22.77764 ? 466  GLN B O   1 
ATOM   7098 C  CB  . GLN B  1 435 ? 5.59856  20.91179  -25.78945 1.000 21.87045 ? 466  GLN B CB  1 
ATOM   7099 C  CG  . GLN B  1 435 ? 5.89479  20.88289  -27.27615 1.000 25.21230 ? 466  GLN B CG  1 
ATOM   7100 C  CD  . GLN B  1 435 ? 5.78173  19.49428  -27.86794 1.000 26.78153 ? 466  GLN B CD  1 
ATOM   7101 O  OE1 . GLN B  1 435 ? 5.08015  18.64091  -27.34089 1.000 30.80125 ? 466  GLN B OE1 1 
ATOM   7102 N  NE2 . GLN B  1 435 ? 6.48752  19.26005  -28.97083 1.000 32.33820 ? 466  GLN B NE2 1 
ATOM   7103 N  N   . GLU B  1 436 ? 4.40934  23.80612  -25.28093 1.000 22.62468 ? 467  GLU B N   1 
ATOM   7104 C  CA  . GLU B  1 436 ? 3.82173  25.04473  -25.78264 1.000 24.31606 ? 467  GLU B CA  1 
ATOM   7105 C  C   . GLU B  1 436 ? 4.68599  26.24629  -25.42551 1.000 23.58520 ? 467  GLU B C   1 
ATOM   7106 O  O   . GLU B  1 436 ? 4.84741  27.16946  -26.23051 1.000 24.74330 ? 467  GLU B O   1 
ATOM   7107 C  CB  . GLU B  1 436 ? 2.40694  25.21332  -25.22487 1.000 27.78975 ? 467  GLU B CB  1 
ATOM   7108 C  CG  . GLU B  1 436 ? 1.66840  26.43816  -25.74579 1.000 32.80478 ? 467  GLU B CG  1 
ATOM   7109 C  CD  . GLU B  1 436 ? 1.20957  26.28375  -27.18781 1.000 39.60433 ? 467  GLU B CD  1 
ATOM   7110 O  OE1 . GLU B  1 436 ? 1.44166  25.20905  -27.78642 1.000 44.28611 ? 467  GLU B OE1 1 
ATOM   7111 O  OE2 . GLU B  1 436 ? 0.60855  27.24231  -27.72019 1.000 52.24611 ? 467  GLU B OE2 1 
ATOM   7112 N  N   . TRP B  1 437 ? 5.24294  26.25220  -24.21423 1.000 21.18783 ? 468  TRP B N   1 
ATOM   7113 C  CA  . TRP B  1 437 ? 6.16942  27.30282  -23.81662 1.000 21.56222 ? 468  TRP B CA  1 
ATOM   7114 C  C   . TRP B  1 437 ? 7.33925  27.41031  -24.79294 1.000 22.36273 ? 468  TRP B C   1 
ATOM   7115 O  O   . TRP B  1 437 ? 7.70603  28.51385  -25.21351 1.000 22.61045 ? 468  TRP B O   1 
ATOM   7116 C  CB  . TRP B  1 437 ? 6.64453  27.02950  -22.38506 1.000 22.95674 ? 468  TRP B CB  1 
ATOM   7117 C  CG  . TRP B  1 437 ? 7.73775  27.91312  -21.84975 1.000 21.52830 ? 468  TRP B CG  1 
ATOM   7118 C  CD1 . TRP B  1 437 ? 7.71187  29.27706  -21.69824 1.000 23.74937 ? 468  TRP B CD1 1 
ATOM   7119 C  CD2 . TRP B  1 437 ? 8.99972  27.47442  -21.32662 1.000 19.25492 ? 468  TRP B CD2 1 
ATOM   7120 N  NE1 . TRP B  1 437 ? 8.89469  29.71094  -21.13750 1.000 22.17621 ? 468  TRP B NE1 1 
ATOM   7121 C  CE2 . TRP B  1 437 ? 9.69886  28.62403  -20.89893 1.000 21.32547 ? 468  TRP B CE2 1 
ATOM   7122 C  CE3 . TRP B  1 437 ? 9.60619  26.21324  -21.17775 1.000 19.10603 ? 468  TRP B CE3 1 
ATOM   7123 C  CZ2 . TRP B  1 437 ? 10.97885 28.55866  -20.33734 1.000 20.23013 ? 468  TRP B CZ2 1 
ATOM   7124 C  CZ3 . TRP B  1 437 ? 10.88311 26.14815  -20.62899 1.000 20.26190 ? 468  TRP B CZ3 1 
ATOM   7125 C  CH2 . TRP B  1 437 ? 11.55906 27.31969  -20.22056 1.000 20.46100 ? 468  TRP B CH2 1 
ATOM   7126 N  N   . THR B  1 438 ? 7.92925  26.27397  -25.18392 1.000 22.00735 ? 469  THR B N   1 
ATOM   7127 C  CA  . THR B  1 438 ? 9.08010  26.33382  -26.08482 1.000 20.92802 ? 469  THR B CA  1 
ATOM   7128 C  C   . THR B  1 438 ? 8.70839  26.88072  -27.45901 1.000 21.11976 ? 469  THR B C   1 
ATOM   7129 O  O   . THR B  1 438 ? 9.59121  27.35780  -28.17582 1.000 23.64553 ? 469  THR B O   1 
ATOM   7130 C  CB  . THR B  1 438 ? 9.74269  24.95925  -26.25323 1.000 22.91421 ? 469  THR B CB  1 
ATOM   7131 O  OG1 . THR B  1 438 ? 8.89586  24.08974  -27.02174 1.000 23.00688 ? 469  THR B OG1 1 
ATOM   7132 C  CG2 . THR B  1 438 ? 10.03921 24.31131  -24.89565 1.000 20.92987 ? 469  THR B CG2 1 
ATOM   7133 N  N   . LYS B  1 439 ? 7.42907  26.82742  -27.84288 1.000 23.54885 ? 470  LYS B N   1 
ATOM   7134 C  CA  . LYS B  1 439 ? 7.05385  27.35453  -29.15199 1.000 25.48636 ? 470  LYS B CA  1 
ATOM   7135 C  C   . LYS B  1 439 ? 7.26711  28.85832  -29.25045 1.000 26.26152 ? 470  LYS B C   1 
ATOM   7136 O  O   . LYS B  1 439 ? 7.34098  29.38584  -30.36508 1.000 28.10930 ? 470  LYS B O   1 
ATOM   7137 C  CB  . LYS B  1 439 ? 5.59823  27.01003  -29.46410 1.000 24.70114 ? 470  LYS B CB  1 
ATOM   7138 C  CG  . LYS B  1 439 ? 5.37564  25.52688  -29.65298 1.000 30.01004 ? 470  LYS B CG  1 
ATOM   7139 C  CD  . LYS B  1 439 ? 3.93400  25.20737  -30.00304 1.000 36.72441 ? 470  LYS B CD  1 
ATOM   7140 C  CE  . LYS B  1 439 ? 3.69820  23.70956  -29.93025 1.000 43.23785 ? 470  LYS B CE  1 
ATOM   7141 N  NZ  . LYS B  1 439 ? 4.83895  22.95487  -30.52348 1.000 49.06237 ? 470  LYS B NZ  1 
ATOM   7142 N  N   . SER B  1 440 ? 7.37861  29.55255  -28.11659 1.000 23.97875 ? 471  SER B N   1 
ATOM   7143 C  CA  . SER B  1 440 ? 7.61857  30.98685  -28.09559 1.000 25.83042 ? 471  SER B CA  1 
ATOM   7144 C  C   . SER B  1 440 ? 9.09589  31.35130  -28.14977 1.000 23.87576 ? 471  SER B C   1 
ATOM   7145 O  O   . SER B  1 440 ? 9.41613  32.54230  -28.24902 1.000 26.22030 ? 471  SER B O   1 
ATOM   7146 C  CB  . SER B  1 440 ? 6.99366  31.60300  -26.83853 1.000 25.88461 ? 471  SER B CB  1 
ATOM   7147 O  OG  . SER B  1 440 ? 7.68860  31.18812  -25.66718 1.000 26.13457 ? 471  SER B OG  1 
ATOM   7148 N  N   . PHE B  1 441 ? 9.99821  30.37123  -28.10433 1.000 23.81954 ? 472  PHE B N   1 
ATOM   7149 C  CA  . PHE B  1 441 ? 11.41722 30.67220  -27.96288 1.000 22.86479 ? 472  PHE B CA  1 
ATOM   7150 C  C   . PHE B  1 441 ? 11.98880 31.31907  -29.22172 1.000 25.17312 ? 472  PHE B C   1 
ATOM   7151 O  O   . PHE B  1 441 ? 11.51208 31.09909  -30.33823 1.000 27.68343 ? 472  PHE B O   1 
ATOM   7152 C  CB  . PHE B  1 441 ? 12.22991 29.40927  -27.67020 1.000 21.28299 ? 472  PHE B CB  1 
ATOM   7153 C  CG  . PHE B  1 441 ? 12.00909 28.83011  -26.29794 1.000 21.75900 ? 472  PHE B CG  1 
ATOM   7154 C  CD1 . PHE B  1 441 ? 11.11266 29.40709  -25.40901 1.000 21.30281 ? 472  PHE B CD1 1 
ATOM   7155 C  CD2 . PHE B  1 441 ? 12.71219 27.69624  -25.90401 1.000 20.31589 ? 472  PHE B CD2 1 
ATOM   7156 C  CE1 . PHE B  1 441 ? 10.91871 28.85341  -24.14784 1.000 19.05713 ? 472  PHE B CE1 1 
ATOM   7157 C  CE2 . PHE B  1 441 ? 12.53030 27.14374  -24.63746 1.000 20.83857 ? 472  PHE B CE2 1 
ATOM   7158 C  CZ  . PHE B  1 441 ? 11.62632 27.72281  -23.76735 1.000 19.00418 ? 472  PHE B CZ  1 
ATOM   7159 N  N   . VAL B  1 442 ? 13.04774 32.09158  -29.02389 1.000 23.79016 ? 473  VAL B N   1 
ATOM   7160 C  CA  . VAL B  1 442 ? 13.82535 32.64178  -30.11344 1.000 25.64013 ? 473  VAL B CA  1 
ATOM   7161 C  C   . VAL B  1 442 ? 15.11578 31.84266  -30.24085 1.000 27.78893 ? 473  VAL B C   1 
ATOM   7162 O  O   . VAL B  1 442 ? 15.43072 30.99297  -29.41165 1.000 24.80022 ? 473  VAL B O   1 
ATOM   7163 C  CB  . VAL B  1 442 ? 14.11408 34.14527  -29.90738 1.000 26.30383 ? 473  VAL B CB  1 
ATOM   7164 C  CG1 . VAL B  1 442 ? 12.82966 34.89314  -29.66704 1.000 25.15672 ? 473  VAL B CG1 1 
ATOM   7165 C  CG2 . VAL B  1 442 ? 15.08287 34.34594  -28.74171 1.000 23.90088 ? 473  VAL B CG2 1 
ATOM   7166 N  N   . LYS B  1 443 ? 15.87293 32.10681  -31.30978 1.000 25.90674 ? 474  LYS B N   1 
ATOM   7167 C  CA  . LYS B  1 443 ? 17.16808 31.46606  -31.46337 1.000 26.31461 ? 474  LYS B CA  1 
ATOM   7168 C  C   . LYS B  1 443 ? 18.18913 32.13419  -30.54725 1.000 21.63520 ? 474  LYS B C   1 
ATOM   7169 O  O   . LYS B  1 443 ? 18.11516 33.34325  -30.30285 1.000 24.57784 ? 474  LYS B O   1 
ATOM   7170 C  CB  . LYS B  1 443 ? 17.64336 31.54863  -32.91321 1.000 32.37641 ? 474  LYS B CB  1 
ATOM   7171 N  N   . PRO B  1 444 ? 19.13897 31.37004  -30.01160 1.000 22.80543 ? 475  PRO B N   1 
ATOM   7172 C  CA  . PRO B  1 444 ? 20.22291 31.99236  -29.23981 1.000 21.69793 ? 475  PRO B CA  1 
ATOM   7173 C  C   . PRO B  1 444 ? 21.01579 32.96155  -30.10621 1.000 23.93772 ? 475  PRO B C   1 
ATOM   7174 O  O   . PRO B  1 444 ? 21.33587 32.67318  -31.26194 1.000 26.70761 ? 475  PRO B O   1 
ATOM   7175 C  CB  . PRO B  1 444 ? 21.08761 30.80491  -28.80390 1.000 26.19284 ? 475  PRO B CB  1 
ATOM   7176 C  CG  . PRO B  1 444 ? 20.23065 29.59922  -28.97989 1.000 30.16539 ? 475  PRO B CG  1 
ATOM   7177 C  CD  . PRO B  1 444 ? 19.28306 29.90732  -30.09531 1.000 24.67608 ? 475  PRO B CD  1 
ATOM   7178 N  N   . LEU B  1 445 ? 21.34176 34.11731  -29.52790 1.000 21.24364 ? 476  LEU B N   1 
ATOM   7179 C  CA  . LEU B  1 445 ? 22.16224 35.09903  -30.24335 1.000 20.43301 ? 476  LEU B CA  1 
ATOM   7180 C  C   . LEU B  1 445 ? 23.60503 34.63304  -30.36911 1.000 26.98093 ? 476  LEU B C   1 
ATOM   7181 O  O   . LEU B  1 445 ? 24.29597 34.99212  -31.32697 1.000 27.40026 ? 476  LEU B O   1 
ATOM   7182 C  CB  . LEU B  1 445 ? 22.09448 36.45031  -29.53313 1.000 21.79972 ? 476  LEU B CB  1 
ATOM   7183 C  CG  . LEU B  1 445 ? 20.71472 37.11462  -29.57764 1.000 24.43729 ? 476  LEU B CG  1 
ATOM   7184 C  CD1 . LEU B  1 445 ? 20.64454 38.20097  -28.52993 1.000 26.21551 ? 476  LEU B CD1 1 
ATOM   7185 C  CD2 . LEU B  1 445 ? 20.44883 37.68452  -30.97658 1.000 29.16650 ? 476  LEU B CD2 1 
ATOM   7186 N  N   . TRP B  1 446 ? 24.07099 33.84419  -29.40964 1.000 20.58442 ? 477  TRP B N   1 
ATOM   7187 C  CA  . TRP B  1 446 ? 25.36393 33.18912  -29.44117 1.000 24.03119 ? 477  TRP B CA  1 
ATOM   7188 C  C   . TRP B  1 446 ? 25.19354 31.83678  -28.77268 1.000 21.34429 ? 477  TRP B C   1 
ATOM   7189 O  O   . TRP B  1 446 ? 24.24775 31.62029  -28.01091 1.000 21.36375 ? 477  TRP B O   1 
ATOM   7190 C  CB  . TRP B  1 446 ? 26.44160 34.00778  -28.71229 1.000 22.42220 ? 477  TRP B CB  1 
ATOM   7191 C  CG  . TRP B  1 446 ? 26.04913 34.32342  -27.28642 1.000 20.26095 ? 477  TRP B CG  1 
ATOM   7192 C  CD1 . TRP B  1 446 ? 26.23974 33.52923  -26.18482 1.000 23.36998 ? 477  TRP B CD1 1 
ATOM   7193 C  CD2 . TRP B  1 446 ? 25.38664 35.50616  -26.81880 1.000 22.54993 ? 477  TRP B CD2 1 
ATOM   7194 N  NE1 . TRP B  1 446 ? 25.74043 34.14978  -25.06546 1.000 20.73881 ? 477  TRP B NE1 1 
ATOM   7195 C  CE2 . TRP B  1 446 ? 25.20372 35.36029  -25.42774 1.000 19.56192 ? 477  TRP B CE2 1 
ATOM   7196 C  CE3 . TRP B  1 446 ? 24.93340 36.67710  -27.44067 1.000 21.85312 ? 477  TRP B CE3 1 
ATOM   7197 C  CZ2 . TRP B  1 446 ? 24.59171 36.33843  -24.65036 1.000 19.91796 ? 477  TRP B CZ2 1 
ATOM   7198 C  CZ3 . TRP B  1 446 ? 24.31836 37.64770  -26.66690 1.000 23.40821 ? 477  TRP B CZ3 1 
ATOM   7199 C  CH2 . TRP B  1 446 ? 24.16020 37.47841  -25.28424 1.000 22.67211 ? 477  TRP B CH2 1 
ATOM   7200 N  N   . VAL B  1 447 ? 26.10743 30.92030  -29.07697 1.000 21.84066 ? 478  VAL B N   1 
ATOM   7201 C  CA  . VAL B  1 447 ? 26.16981 29.64893  -28.36215 1.000 19.75524 ? 478  VAL B CA  1 
ATOM   7202 C  C   . VAL B  1 447 ? 27.49953 29.61595  -27.61864 1.000 20.33783 ? 478  VAL B C   1 
ATOM   7203 O  O   . VAL B  1 447 ? 28.19835 30.63312  -27.54907 1.000 23.30782 ? 478  VAL B O   1 
ATOM   7204 C  CB  . VAL B  1 447 ? 25.98913 28.45643  -29.31200 1.000 20.66872 ? 478  VAL B CB  1 
ATOM   7205 C  CG1 . VAL B  1 447 ? 24.61015 28.50193  -29.96189 1.000 23.52640 ? 478  VAL B CG1 1 
ATOM   7206 C  CG2 . VAL B  1 447 ? 27.08583 28.44272  -30.36668 1.000 24.46758 ? 478  VAL B CG2 1 
ATOM   7207 N  N   . TYR B  1 448 ? 27.85422 28.47458  -27.02005 1.000 19.90549 ? 479  TYR B N   1 
ATOM   7208 C  CA  . TYR B  1 448 ? 29.04442 28.44776  -26.18117 1.000 19.21028 ? 479  TYR B CA  1 
ATOM   7209 C  C   . TYR B  1 448 ? 30.23104 27.75755  -26.84515 1.000 21.09149 ? 479  TYR B C   1 
ATOM   7210 O  O   . TYR B  1 448 ? 31.34043 28.29391  -26.81816 1.000 23.02303 ? 479  TYR B O   1 
ATOM   7211 C  CB  . TYR B  1 448 ? 28.74466 27.77579  -24.82817 1.000 18.63147 ? 479  TYR B CB  1 
ATOM   7212 C  CG  . TYR B  1 448 ? 29.80437 28.05551  -23.77543 1.000 18.14358 ? 479  TYR B CG  1 
ATOM   7213 C  CD1 . TYR B  1 448 ? 29.90514 29.32294  -23.18294 1.000 19.83582 ? 479  TYR B CD1 1 
ATOM   7214 C  CD2 . TYR B  1 448 ? 30.71113 27.07890  -23.38685 1.000 22.69685 ? 479  TYR B CD2 1 
ATOM   7215 C  CE1 . TYR B  1 448 ? 30.87101 29.58817  -22.22796 1.000 20.10195 ? 479  TYR B CE1 1 
ATOM   7216 C  CE2 . TYR B  1 448 ? 31.68184 27.34064  -22.42733 1.000 24.11990 ? 479  TYR B CE2 1 
ATOM   7217 C  CZ  . TYR B  1 448 ? 31.75414 28.59921  -21.85573 1.000 23.64897 ? 479  TYR B CZ  1 
ATOM   7218 O  OH  . TYR B  1 448 ? 32.70832 28.86528  -20.89776 1.000 25.00873 ? 479  TYR B OH  1 
ATOM   7219 N  N   . SER B  1 449 ? 30.03271 26.57831  -27.43216 1.000 18.91056 ? 480  SER B N   1 
ATOM   7220 C  CA  . SER B  1 449 ? 31.13510 25.81799  -28.00659 1.000 19.81478 ? 480  SER B CA  1 
ATOM   7221 C  C   . SER B  1 449 ? 30.99004 25.68061  -29.51764 1.000 21.17383 ? 480  SER B C   1 
ATOM   7222 O  O   . SER B  1 449 ? 29.91561 25.88727  -30.08542 1.000 18.68960 ? 480  SER B O   1 
ATOM   7223 C  CB  . SER B  1 449 ? 31.21719 24.41504  -27.38884 1.000 20.89417 ? 480  SER B CB  1 
ATOM   7224 O  OG  . SER B  1 449 ? 30.05068 23.67117  -27.71091 1.000 20.83835 ? 480  SER B OG  1 
ATOM   7225 N  N   . VAL B  1 450 ? 32.10094 25.30106  -30.15946 1.000 21.33000 ? 481  VAL B N   1 
ATOM   7226 C  CA  . VAL B  1 450 ? 32.06165 24.95246  -31.57928 1.000 21.65023 ? 481  VAL B CA  1 
ATOM   7227 C  C   . VAL B  1 450 ? 31.04845 23.84121  -31.82797 1.000 21.36514 ? 481  VAL B C   1 
ATOM   7228 O  O   . VAL B  1 450 ? 30.29911 23.87303  -32.80978 1.000 21.06407 ? 481  VAL B O   1 
ATOM   7229 C  CB  . VAL B  1 450 ? 33.46971 24.56343  -32.07040 1.000 20.74064 ? 481  VAL B CB  1 
ATOM   7230 C  CG1 . VAL B  1 450 ? 33.40371 23.97381  -33.48998 1.000 23.22785 ? 481  VAL B CG1 1 
ATOM   7231 C  CG2 . VAL B  1 450 ? 34.38925 25.76865  -32.02696 1.000 22.17831 ? 481  VAL B CG2 1 
ATOM   7232 N  N   . LYS B  1 451 ? 30.98160 22.86255  -30.92037 1.000 19.45487 ? 482  LYS B N   1 
ATOM   7233 C  CA  . LYS B  1 451 ? 29.99437 21.79373  -31.03650 1.000 21.29168 ? 482  LYS B CA  1 
ATOM   7234 C  C   . LYS B  1 451 ? 28.57253 22.35302  -31.05761 1.000 19.35461 ? 482  LYS B C   1 
ATOM   7235 O  O   . LYS B  1 451 ? 27.74958 21.94999  -31.88582 1.000 19.61495 ? 482  LYS B O   1 
ATOM   7236 C  CB  . LYS B  1 451 ? 30.18007 20.80947  -29.87967 1.000 19.27364 ? 482  LYS B CB  1 
ATOM   7237 C  CG  . LYS B  1 451 ? 29.24036 19.62686  -29.90057 1.000 21.18215 ? 482  LYS B CG  1 
ATOM   7238 C  CD  . LYS B  1 451 ? 29.52051 18.71722  -31.07105 1.000 23.34841 ? 482  LYS B CD  1 
ATOM   7239 C  CE  . LYS B  1 451 ? 28.64094 17.46774  -31.03768 1.000 23.47350 ? 482  LYS B CE  1 
ATOM   7240 N  NZ  . LYS B  1 451 ? 28.96160 16.58129  -32.19227 1.000 22.58678 ? 482  LYS B NZ  1 
ATOM   7241 N  N   . ASP B  1 452 ? 28.26700 23.28361  -30.14631 1.000 18.50752 ? 483  ASP B N   1 
ATOM   7242 C  CA  . ASP B  1 452 ? 26.96485 23.95038  -30.15632 1.000 20.04653 ? 483  ASP B CA  1 
ATOM   7243 C  C   . ASP B  1 452 ? 26.66302 24.53569  -31.52436 1.000 19.99736 ? 483  ASP B C   1 
ATOM   7244 O  O   . ASP B  1 452 ? 25.56636 24.35501  -32.06713 1.000 21.86735 ? 483  ASP B O   1 
ATOM   7245 C  CB  . ASP B  1 452 ? 26.92250 25.09569  -29.14623 1.000 19.51825 ? 483  ASP B CB  1 
ATOM   7246 C  CG  . ASP B  1 452 ? 26.98993 24.64454  -27.70995 1.000 20.01973 ? 483  ASP B CG  1 
ATOM   7247 O  OD1 . ASP B  1 452 ? 26.59649 23.50099  -27.40887 1.000 21.35058 ? 483  ASP B OD1 1 
ATOM   7248 O  OD2 . ASP B  1 452 ? 27.38914 25.49291  -26.88816 1.000 19.18717 ? 483  ASP B OD2 1 
ATOM   7249 N  N   . LYS B  1 453 ? 27.62790 25.27920  -32.07119 1.000 20.95808 ? 484  LYS B N   1 
ATOM   7250 C  CA  . LYS B  1 453 ? 27.42546 25.94530  -33.35600 1.000 21.70270 ? 484  LYS B CA  1 
ATOM   7251 C  C   . LYS B  1 453 ? 27.12073 24.92993  -34.44579 1.000 20.75559 ? 484  LYS B C   1 
ATOM   7252 O  O   . LYS B  1 453 ? 26.17746 25.10423  -35.22607 1.000 24.11829 ? 484  LYS B O   1 
ATOM   7253 C  CB  . LYS B  1 453 ? 28.65740 26.76744  -33.72204 1.000 21.41986 ? 484  LYS B CB  1 
ATOM   7254 C  CG  . LYS B  1 453 ? 28.51877 27.50459  -35.06218 1.000 29.80068 ? 484  LYS B CG  1 
ATOM   7255 C  CD  . LYS B  1 453 ? 29.69603 28.43687  -35.28481 1.000 34.83122 ? 484  LYS B CD  1 
ATOM   7256 C  CE  . LYS B  1 453 ? 29.72886 28.98071  -36.71118 1.000 42.54830 ? 484  LYS B CE  1 
ATOM   7257 N  NZ  . LYS B  1 453 ? 30.17175 27.93353  -37.68058 1.000 48.11382 ? 484  LYS B NZ  1 
ATOM   7258 N  N   . GLU B  1 454 ? 27.89318 23.84134  -34.49162 1.000 21.88081 ? 485  GLU B N   1 
ATOM   7259 C  CA  . GLU B  1 454 ? 27.63318 22.79065  -35.47390 1.000 21.26525 ? 485  GLU B CA  1 
ATOM   7260 C  C   . GLU B  1 454 ? 26.23907 22.20798  -35.30965 1.000 24.60522 ? 485  GLU B C   1 
ATOM   7261 O  O   . GLU B  1 454 ? 25.54526 21.95114  -36.30148 1.000 23.05709 ? 485  GLU B O   1 
ATOM   7262 C  CB  . GLU B  1 454 ? 28.68136 21.68453  -35.35828 1.000 23.39565 ? 485  GLU B CB  1 
ATOM   7263 C  CG  . GLU B  1 454 ? 30.03644 22.09940  -35.85029 1.000 25.88521 ? 485  GLU B CG  1 
ATOM   7264 C  CD  . GLU B  1 454 ? 31.07988 21.03272  -35.63878 1.000 23.57546 ? 485  GLU B CD  1 
ATOM   7265 O  OE1 . GLU B  1 454 ? 30.71825 19.91969  -35.20158 1.000 26.16517 ? 485  GLU B OE1 1 
ATOM   7266 O  OE2 . GLU B  1 454 ? 32.26097 21.32078  -35.90311 1.000 30.39257 ? 485  GLU B OE2 1 
ATOM   7267 N  N   . LEU B  1 455 ? 25.81096 21.98439  -34.06393 1.000 22.68901 ? 486  LEU B N   1 
ATOM   7268 C  CA  . LEU B  1 455 ? 24.53030 21.32431  -33.83872 1.000 21.10919 ? 486  LEU B CA  1 
ATOM   7269 C  C   . LEU B  1 455 ? 23.36119 22.22740  -34.20362 1.000 22.17816 ? 486  LEU B C   1 
ATOM   7270 O  O   . LEU B  1 455 ? 22.37612 21.76541  -34.79168 1.000 23.51677 ? 486  LEU B O   1 
ATOM   7271 C  CB  . LEU B  1 455 ? 24.41853 20.87813  -32.38143 1.000 22.45191 ? 486  LEU B CB  1 
ATOM   7272 C  CG  . LEU B  1 455 ? 25.34903 19.76216  -31.92140 1.000 24.50378 ? 486  LEU B CG  1 
ATOM   7273 C  CD1 . LEU B  1 455 ? 25.25496 19.63907  -30.40816 1.000 25.10240 ? 486  LEU B CD1 1 
ATOM   7274 C  CD2 . LEU B  1 455 ? 24.99553 18.44001  -32.59881 1.000 27.73165 ? 486  LEU B CD2 1 
ATOM   7275 N  N   . TRP B  1 456 ? 23.43373 23.51048  -33.83904 1.000 21.38708 ? 487  TRP B N   1 
ATOM   7276 C  CA  . TRP B  1 456 ? 22.36713 24.43528  -34.21244 1.000 21.32632 ? 487  TRP B CA  1 
ATOM   7277 C  C   . TRP B  1 456 ? 22.34183 24.67157  -35.72045 1.000 23.37418 ? 487  TRP B C   1 
ATOM   7278 O  O   . TRP B  1 456 ? 21.26737 24.74865  -36.32294 1.000 25.04574 ? 487  TRP B O   1 
ATOM   7279 C  CB  . TRP B  1 456 ? 22.53044 25.75895  -33.46052 1.000 22.35715 ? 487  TRP B CB  1 
ATOM   7280 C  CG  . TRP B  1 456 ? 22.06399 25.70812  -32.02403 1.000 22.85881 ? 487  TRP B CG  1 
ATOM   7281 C  CD1 . TRP B  1 456 ? 22.80072 25.32961  -30.93797 1.000 22.68814 ? 487  TRP B CD1 1 
ATOM   7282 C  CD2 . TRP B  1 456 ? 20.76228 26.05985  -31.52554 1.000 22.79212 ? 487  TRP B CD2 1 
ATOM   7283 N  NE1 . TRP B  1 456 ? 22.03245 25.41064  -29.79481 1.000 21.90069 ? 487  TRP B NE1 1 
ATOM   7284 C  CE2 . TRP B  1 456 ? 20.78404 25.86667  -30.12936 1.000 21.85502 ? 487  TRP B CE2 1 
ATOM   7285 C  CE3 . TRP B  1 456 ? 19.58557 26.52710  -32.12346 1.000 24.20410 ? 487  TRP B CE3 1 
ATOM   7286 C  CZ2 . TRP B  1 456 ? 19.66837 26.11278  -29.32289 1.000 22.33450 ? 487  TRP B CZ2 1 
ATOM   7287 C  CZ3 . TRP B  1 456 ? 18.47907 26.77508  -31.32351 1.000 25.10863 ? 487  TRP B CZ3 1 
ATOM   7288 C  CH2 . TRP B  1 456 ? 18.53089 26.57048  -29.93542 1.000 23.54457 ? 487  TRP B CH2 1 
ATOM   7289 N  N   . GLU B  1 457 ? 23.50887 24.79257  -36.34797 1.000 26.77618 ? 488  GLU B N   1 
ATOM   7290 C  CA  . GLU B  1 457 ? 23.51893 25.06202  -37.78470 1.000 27.75596 ? 488  GLU B CA  1 
ATOM   7291 C  C   . GLU B  1 457 ? 23.00265 23.88027  -38.59004 1.000 31.27541 ? 488  GLU B C   1 
ATOM   7292 O  O   . GLU B  1 457 ? 22.39799 24.07487  -39.65154 1.000 28.40188 ? 488  GLU B O   1 
ATOM   7293 C  CB  . GLU B  1 457 ? 24.92034 25.45211  -38.23553 1.000 29.43786 ? 488  GLU B CB  1 
ATOM   7294 C  CG  . GLU B  1 457 ? 25.31805 26.81409  -37.71003 1.000 31.02772 ? 488  GLU B CG  1 
ATOM   7295 C  CD  . GLU B  1 457 ? 26.58118 27.35937  -38.34118 1.000 37.70197 ? 488  GLU B CD  1 
ATOM   7296 O  OE1 . GLU B  1 457 ? 27.35899 26.57190  -38.91992 1.000 37.69873 ? 488  GLU B OE1 1 
ATOM   7297 O  OE2 . GLU B  1 457 ? 26.79154 28.58477  -38.24753 1.000 40.79157 ? 488  GLU B OE2 1 
ATOM   7298 N  N   . SER B  1 458 ? 23.21199 22.65785  -38.10695 1.000 26.59957 ? 489  SER B N   1 
ATOM   7299 C  CA  . SER B  1 458 ? 22.70059 21.48909  -38.80878 1.000 26.56932 ? 489  SER B CA  1 
ATOM   7300 C  C   . SER B  1 458 ? 21.22924 21.22847  -38.53489 1.000 30.54891 ? 489  SER B C   1 
ATOM   7301 O  O   . SER B  1 458 ? 20.61434 20.43974  -39.25748 1.000 32.36841 ? 489  SER B O   1 
ATOM   7302 C  CB  . SER B  1 458 ? 23.51282 20.24580  -38.43266 1.000 28.03583 ? 489  SER B CB  1 
ATOM   7303 O  OG  . SER B  1 458 ? 23.21676 19.83791  -37.10814 1.000 28.73188 ? 489  SER B OG  1 
ATOM   7304 N  N   . GLY B  1 459 ? 20.64848 21.86133  -37.51738 1.000 26.03341 ? 490  GLY B N   1 
ATOM   7305 C  CA  . GLY B  1 459 ? 19.29815 21.54981  -37.11356 1.000 25.79583 ? 490  GLY B CA  1 
ATOM   7306 C  C   . GLY B  1 459 ? 19.18144 20.41930  -36.11299 1.000 25.45213 ? 490  GLY B C   1 
ATOM   7307 O  O   . GLY B  1 459 ? 18.05888 20.09933  -35.69446 1.000 27.93779 ? 490  GLY B O   1 
ATOM   7308 N  N   . GLN B  1 460 ? 20.29904 19.79629  -35.72245 1.000 25.33646 ? 491  GLN B N   1 
ATOM   7309 C  CA  . GLN B  1 460 ? 20.24161 18.77341  -34.68140 1.000 24.71553 ? 491  GLN B CA  1 
ATOM   7310 C  C   . GLN B  1 460 ? 19.79813 19.37250  -33.35424 1.000 27.17579 ? 491  GLN B C   1 
ATOM   7311 O  O   . GLN B  1 460 ? 19.11220 18.70568  -32.56825 1.000 26.56022 ? 491  GLN B O   1 
ATOM   7312 C  CB  . GLN B  1 460 ? 21.60128 18.08344  -34.52969 1.000 28.01887 ? 491  GLN B CB  1 
ATOM   7313 C  CG  . GLN B  1 460 ? 22.01268 17.24998  -35.73876 1.000 35.50827 ? 491  GLN B CG  1 
ATOM   7314 C  CD  . GLN B  1 460 ? 23.50205 16.94759  -35.75821 1.000 43.29997 ? 491  GLN B CD  1 
ATOM   7315 O  OE1 . GLN B  1 460 ? 24.25874 17.53554  -36.53707 1.000 43.02078 ? 491  GLN B OE1 1 
ATOM   7316 N  NE2 . GLN B  1 460 ? 23.93213 16.03426  -34.89357 1.000 44.43988 ? 491  GLN B NE2 1 
ATOM   7317 N  N   . MET B  1 461 ? 20.19115 20.62237  -33.08421 1.000 22.97158 ? 492  MET B N   1 
ATOM   7318 C  CA  . MET B  1 461 ? 19.63865 21.42206  -32.00383 1.000 20.71221 ? 492  MET B CA  1 
ATOM   7319 C  C   . MET B  1 461 ? 18.69976 22.47737  -32.57606 1.000 24.07644 ? 492  MET B C   1 
ATOM   7320 O  O   . MET B  1 461 ? 18.94290 23.00333  -33.66648 1.000 24.02051 ? 492  MET B O   1 
ATOM   7321 C  CB  . MET B  1 461 ? 20.74064 22.10782  -31.18734 1.000 21.44802 ? 492  MET B CB  1 
ATOM   7322 C  CG  . MET B  1 461 ? 21.52034 21.14371  -30.28810 1.000 22.82719 ? 492  MET B CG  1 
ATOM   7323 S  SD  . MET B  1 461 ? 20.54973 20.48287  -28.90691 1.000 23.39756 ? 492  MET B SD  1 
ATOM   7324 C  CE  . MET B  1 461 ? 20.55843 21.87258  -27.77373 1.000 18.34260 ? 492  MET B CE  1 
ATOM   7325 N  N   . PRO B  1 462 ? 17.63706 22.83670  -31.85160 1.000 22.39897 ? 493  PRO B N   1 
ATOM   7326 C  CA  . PRO B  1 462 ? 17.30060 22.39374  -30.48736 1.000 20.99765 ? 493  PRO B CA  1 
ATOM   7327 C  C   . PRO B  1 462 ? 16.42992 21.14765  -30.41542 1.000 23.53392 ? 493  PRO B C   1 
ATOM   7328 O  O   . PRO B  1 462 ? 16.32406 20.53688  -29.34882 1.000 22.10696 ? 493  PRO B O   1 
ATOM   7329 C  CB  . PRO B  1 462 ? 16.55819 23.61223  -29.92916 1.000 23.25494 ? 493  PRO B CB  1 
ATOM   7330 C  CG  . PRO B  1 462 ? 15.81177 24.13921  -31.14126 1.000 23.89254 ? 493  PRO B CG  1 
ATOM   7331 C  CD  . PRO B  1 462 ? 16.74000 23.91311  -32.31321 1.000 22.53598 ? 493  PRO B CD  1 
ATOM   7332 N  N   . ASN B  1 463 ? 15.78328 20.79051  -31.52284 1.000 20.39350 ? 494  ASN B N   1 
ATOM   7333 C  CA  . ASN B  1 463 ? 14.86297 19.65433  -31.62084 1.000 23.74269 ? 494  ASN B CA  1 
ATOM   7334 C  C   . ASN B  1 463 ? 13.96971 19.52423  -30.38096 1.000 24.12553 ? 494  ASN B C   1 
ATOM   7335 O  O   . ASN B  1 463 ? 14.00205 18.52399  -29.66088 1.000 21.66347 ? 494  ASN B O   1 
ATOM   7336 C  CB  . ASN B  1 463 ? 15.63340 18.36067  -31.86854 1.000 24.03783 ? 494  ASN B CB  1 
ATOM   7337 C  CG  . ASN B  1 463 ? 14.76519 17.26396  -32.45051 1.000 22.80672 ? 494  ASN B CG  1 
ATOM   7338 O  OD1 . ASN B  1 463 ? 13.53558 17.37285  -32.49575 1.000 26.94020 ? 494  ASN B OD1 1 
ATOM   7339 N  ND2 . ASN B  1 463 ? 15.40555 16.19697  -32.90427 1.000 29.23920 ? 494  ASN B ND2 1 
ATOM   7340 N  N   . TYR B  1 464 ? 13.15859 20.56345  -30.14153 1.000 21.78709 ? 495  TYR B N   1 
ATOM   7341 C  CA  . TYR B  1 464 ? 12.20691 20.50299  -29.03471 1.000 19.72872 ? 495  TYR B CA  1 
ATOM   7342 C  C   . TYR B  1 464 ? 11.21591 19.35623  -29.20213 1.000 23.84192 ? 495  TYR B C   1 
ATOM   7343 O  O   . TYR B  1 464 ? 10.75970 18.78979  -28.20462 1.000 20.98833 ? 495  TYR B O   1 
ATOM   7344 C  CB  . TYR B  1 464 ? 11.45010 21.83098  -28.87600 1.000 20.15471 ? 495  TYR B CB  1 
ATOM   7345 C  CG  . TYR B  1 464 ? 12.35604 23.02821  -28.64725 1.000 19.60948 ? 495  TYR B CG  1 
ATOM   7346 C  CD1 . TYR B  1 464 ? 13.20907 23.08451  -27.54527 1.000 19.48459 ? 495  TYR B CD1 1 
ATOM   7347 C  CD2 . TYR B  1 464 ? 12.35535 24.10101  -29.52631 1.000 22.52696 ? 495  TYR B CD2 1 
ATOM   7348 C  CE1 . TYR B  1 464 ? 14.04344 24.15819  -27.33788 1.000 20.16987 ? 495  TYR B CE1 1 
ATOM   7349 C  CE2 . TYR B  1 464 ? 13.18203 25.20036  -29.32390 1.000 20.92239 ? 495  TYR B CE2 1 
ATOM   7350 C  CZ  . TYR B  1 464 ? 14.03495 25.22228  -28.22764 1.000 21.74900 ? 495  TYR B CZ  1 
ATOM   7351 O  OH  . TYR B  1 464 ? 14.86480 26.29693  -28.03266 1.000 21.84037 ? 495  TYR B OH  1 
ATOM   7352 N  N   . GLU B  1 465 ? 10.86427 18.99565  -30.44313 1.000 23.38898 ? 496  GLU B N   1 
ATOM   7353 C  CA  . GLU B  1 465 ? 9.93771  17.87820  -30.63898 1.000 22.54356 ? 496  GLU B CA  1 
ATOM   7354 C  C   . GLU B  1 465 ? 10.46165 16.59855  -29.99438 1.000 20.36987 ? 496  GLU B C   1 
ATOM   7355 O  O   . GLU B  1 465 ? 9.70957  15.87547  -29.33094 1.000 23.65007 ? 496  GLU B O   1 
ATOM   7356 C  CB  . GLU B  1 465 ? 9.67975  17.64466  -32.13059 1.000 26.16081 ? 496  GLU B CB  1 
ATOM   7357 N  N   . ALA B  1 466 ? 11.74778 16.30303  -30.17919 1.000 21.27114 ? 497  ALA B N   1 
ATOM   7358 C  CA  . ALA B  1 466 ? 12.32462 15.10859  -29.57057 1.000 23.88082 ? 497  ALA B CA  1 
ATOM   7359 C  C   . ALA B  1 466 ? 12.37225 15.22967  -28.05192 1.000 21.13604 ? 497  ALA B C   1 
ATOM   7360 O  O   . ALA B  1 466 ? 12.16281 14.23843  -27.34139 1.000 20.30207 ? 497  ALA B O   1 
ATOM   7361 C  CB  . ALA B  1 466 ? 13.72253 14.85538  -30.13124 1.000 24.83839 ? 497  ALA B CB  1 
ATOM   7362 N  N   . THR B  1 467 ? 12.64959 16.43507  -27.54058 1.000 19.82324 ? 498  THR B N   1 
ATOM   7363 C  CA  . THR B  1 467 ? 12.66874 16.64283  -26.09179 1.000 20.76521 ? 498  THR B CA  1 
ATOM   7364 C  C   . THR B  1 467 ? 11.35982 16.20784  -25.44595 1.000 20.37740 ? 498  THR B C   1 
ATOM   7365 O  O   . THR B  1 467 ? 11.35139 15.67383  -24.33047 1.000 19.09716 ? 498  THR B O   1 
ATOM   7366 C  CB  . THR B  1 467 ? 12.95328 18.11359  -25.78662 1.000 20.53186 ? 498  THR B CB  1 
ATOM   7367 O  OG1 . THR B  1 467 ? 14.29135 18.43285  -26.19633 1.000 21.56192 ? 498  THR B OG1 1 
ATOM   7368 C  CG2 . THR B  1 467 ? 12.77568 18.41788  -24.28694 1.000 19.41099 ? 498  THR B CG2 1 
ATOM   7369 N  N   . PHE B  1 468 ? 10.24067 16.40421  -26.13740 1.000 18.01723 ? 499  PHE B N   1 
ATOM   7370 C  CA  . PHE B  1 468 ? 8.94375  16.12692  -25.54485 1.000 18.82351 ? 499  PHE B CA  1 
ATOM   7371 C  C   . PHE B  1 468 ? 8.34972  14.79298  -25.99010 1.000 21.44702 ? 499  PHE B C   1 
ATOM   7372 O  O   . PHE B  1 468 ? 7.17109  14.53002  -25.72458 1.000 24.51264 ? 499  PHE B O   1 
ATOM   7373 C  CB  . PHE B  1 468 ? 8.01935  17.31460  -25.80874 1.000 19.26065 ? 499  PHE B CB  1 
ATOM   7374 C  CG  . PHE B  1 468 ? 8.53391  18.57216  -25.16438 1.000 18.45006 ? 499  PHE B CG  1 
ATOM   7375 C  CD1 . PHE B  1 468 ? 8.63206  18.65368  -23.77918 1.000 19.94411 ? 499  PHE B CD1 1 
ATOM   7376 C  CD2 . PHE B  1 468 ? 9.00170  19.62850  -25.92604 1.000 21.23717 ? 499  PHE B CD2 1 
ATOM   7377 C  CE1 . PHE B  1 468 ? 9.13980  19.78894  -23.16982 1.000 21.53904 ? 499  PHE B CE1 1 
ATOM   7378 C  CE2 . PHE B  1 468 ? 9.50670  20.76985  -25.32628 1.000 22.72694 ? 499  PHE B CE2 1 
ATOM   7379 C  CZ  . PHE B  1 468 ? 9.58135  20.84898  -23.94293 1.000 22.36853 ? 499  PHE B CZ  1 
ATOM   7380 N  N   . GLU B  1 469 ? 9.16099  13.91816  -26.58565 1.000 20.67729 ? 500  GLU B N   1 
ATOM   7381 C  CA  . GLU B  1 469 ? 8.78748  12.51352  -26.70916 1.000 20.98340 ? 500  GLU B CA  1 
ATOM   7382 C  C   . GLU B  1 469 ? 8.63037  11.90452  -25.32072 1.000 21.20795 ? 500  GLU B C   1 
ATOM   7383 O  O   . GLU B  1 469 ? 9.32701  12.28430  -24.37649 1.000 22.33196 ? 500  GLU B O   1 
ATOM   7384 C  CB  . GLU B  1 469 ? 9.85402  11.74721  -27.49096 1.000 21.12460 ? 500  GLU B CB  1 
ATOM   7385 C  CG  . GLU B  1 469 ? 9.94473  12.17641  -28.94405 1.000 23.19694 ? 500  GLU B CG  1 
ATOM   7386 C  CD  . GLU B  1 469 ? 11.18258 11.67006  -29.64942 1.000 25.49786 ? 500  GLU B CD  1 
ATOM   7387 O  OE1 . GLU B  1 469 ? 12.20034 11.38934  -28.98491 1.000 23.03988 ? 500  GLU B OE1 1 
ATOM   7388 O  OE2 . GLU B  1 469 ? 11.14124 11.57024  -30.89035 1.000 25.27398 ? 500  GLU B OE2 1 
ATOM   7389 N  N   . VAL B  1 470 ? 7.69815  10.95984  -25.19365 1.000 21.67945 ? 501  VAL B N   1 
ATOM   7390 C  CA  . VAL B  1 470 ? 7.46215  10.29541  -23.91263 1.000 19.05187 ? 501  VAL B CA  1 
ATOM   7391 C  C   . VAL B  1 470 ? 7.45583  8.77959   -24.07206 1.000 19.22061 ? 501  VAL B C   1 
ATOM   7392 O  O   . VAL B  1 470 ? 8.33824  8.08938   -23.55303 1.000 20.12952 ? 501  VAL B O   1 
ATOM   7393 C  CB  . VAL B  1 470 ? 6.14103  10.76906  -23.27465 1.000 22.90347 ? 501  VAL B CB  1 
ATOM   7394 C  CG1 . VAL B  1 470 ? 5.92780  10.08459  -21.92514 1.000 23.65657 ? 501  VAL B CG1 1 
ATOM   7395 C  CG2 . VAL B  1 470 ? 6.12499  12.27627  -23.11776 1.000 25.23962 ? 501  VAL B CG2 1 
ATOM   7396 N  N   . ASP B  1 471 ? 6.45093  8.24951   -24.78246 1.000 18.97247 ? 502  ASP B N   1 
ATOM   7397 C  CA  . ASP B  1 471 ? 6.20720  6.81025   -24.78080 1.000 23.86845 ? 502  ASP B CA  1 
ATOM   7398 C  C   . ASP B  1 471 ? 7.38296  6.02803   -25.36226 1.000 19.89268 ? 502  ASP B C   1 
ATOM   7399 O  O   . ASP B  1 471 ? 7.74315  4.96352   -24.84669 1.000 22.33690 ? 502  ASP B O   1 
ATOM   7400 C  CB  . ASP B  1 471 ? 4.93307  6.49232   -25.56788 1.000 23.43816 ? 502  ASP B CB  1 
ATOM   7401 C  CG  . ASP B  1 471 ? 3.67676  7.04997   -24.92091 1.000 30.89612 ? 502  ASP B CG  1 
ATOM   7402 O  OD1 . ASP B  1 471 ? 3.70616  7.41090   -23.72672 1.000 30.65882 ? 502  ASP B OD1 1 
ATOM   7403 O  OD2 . ASP B  1 471 ? 2.64009  7.10371   -25.61785 1.000 35.69968 ? 502  ASP B OD2 1 
ATOM   7404 N  N   . LYS B  1 472 ? 7.98319  6.52289   -26.44517 1.000 20.70491 ? 503  LYS B N   1 
ATOM   7405 C  CA  . LYS B  1 472 ? 9.05401  5.76657   -27.08720 1.000 22.58618 ? 503  LYS B CA  1 
ATOM   7406 C  C   . LYS B  1 472 ? 10.29119 5.65135   -26.20254 1.000 20.89793 ? 503  LYS B C   1 
ATOM   7407 O  O   . LYS B  1 472 ? 11.14548 4.79721   -26.45974 1.000 20.51301 ? 503  LYS B O   1 
ATOM   7408 C  CB  . LYS B  1 472 ? 9.42499  6.40294   -28.43163 1.000 23.85420 ? 503  LYS B CB  1 
ATOM   7409 C  CG  . LYS B  1 472 ? 10.13492 7.74243   -28.32654 1.000 22.43481 ? 503  LYS B CG  1 
ATOM   7410 C  CD  . LYS B  1 472 ? 10.70896 8.19842   -29.67994 1.000 24.99428 ? 503  LYS B CD  1 
ATOM   7411 C  CE  . LYS B  1 472 ? 9.61496  8.46277   -30.70850 1.000 25.52374 ? 503  LYS B CE  1 
ATOM   7412 N  NZ  . LYS B  1 472 ? 10.18967 9.00480   -31.97917 1.000 23.71410 ? 503  LYS B NZ  1 
ATOM   7413 N  N   . LEU B  1 473 ? 10.40100 6.47967   -25.16080 1.000 20.33294 ? 504  LEU B N   1 
ATOM   7414 C  CA  . LEU B  1 473 ? 11.53627 6.37263   -24.25150 1.000 18.21301 ? 504  LEU B CA  1 
ATOM   7415 C  C   . LEU B  1 473 ? 11.40424 5.20451   -23.28674 1.000 20.99325 ? 504  LEU B C   1 
ATOM   7416 O  O   . LEU B  1 473 ? 12.41908 4.74991   -22.74779 1.000 20.98081 ? 504  LEU B O   1 
ATOM   7417 C  CB  . LEU B  1 473 ? 11.69921 7.66802   -23.45227 1.000 18.05670 ? 504  LEU B CB  1 
ATOM   7418 C  CG  . LEU B  1 473 ? 11.68388 8.95317   -24.29333 1.000 18.30919 ? 504  LEU B CG  1 
ATOM   7419 C  CD1 . LEU B  1 473 ? 11.78156 10.20944  -23.39911 1.000 21.14524 ? 504  LEU B CD1 1 
ATOM   7420 C  CD2 . LEU B  1 473 ? 12.81725 8.93251   -25.29672 1.000 21.01596 ? 504  LEU B CD2 1 
ATOM   7421 N  N   . VAL B  1 474 ? 10.18760 4.70872   -23.05969 1.000 20.97598 ? 505  VAL B N   1 
ATOM   7422 C  CA  . VAL B  1 474 ? 9.96863  3.63832   -22.09618 1.000 21.80080 ? 505  VAL B CA  1 
ATOM   7423 C  C   . VAL B  1 474 ? 9.42049  2.36149   -22.72134 1.000 22.59869 ? 505  VAL B C   1 
ATOM   7424 O  O   . VAL B  1 474 ? 9.59706  1.28407   -22.13340 1.000 23.86729 ? 505  VAL B O   1 
ATOM   7425 C  CB  . VAL B  1 474 ? 9.04562  4.10406   -20.95211 1.000 21.65832 ? 505  VAL B CB  1 
ATOM   7426 C  CG1 . VAL B  1 474 ? 9.69996  5.26974   -20.20899 1.000 22.42364 ? 505  VAL B CG1 1 
ATOM   7427 C  CG2 . VAL B  1 474 ? 7.68036  4.50085   -21.49405 1.000 23.22440 ? 505  VAL B CG2 1 
ATOM   7428 N  N   . ASP B  1 475 ? 8.78146  2.42473   -23.88743 1.000 22.70017 ? 506  ASP B N   1 
ATOM   7429 C  CA  . ASP B  1 475 ? 8.24160  1.22332   -24.50886 1.000 21.03518 ? 506  ASP B CA  1 
ATOM   7430 C  C   . ASP B  1 475 ? 9.35687  0.34462   -25.06426 1.000 19.17774 ? 506  ASP B C   1 
ATOM   7431 O  O   . ASP B  1 475 ? 10.34997 0.84068   -25.59793 1.000 22.53382 ? 506  ASP B O   1 
ATOM   7432 C  CB  . ASP B  1 475 ? 7.29521  1.59060   -25.64962 1.000 21.38375 ? 506  ASP B CB  1 
ATOM   7433 C  CG  . ASP B  1 475 ? 6.03030  2.29758   -25.17662 1.000 25.68450 ? 506  ASP B CG  1 
ATOM   7434 O  OD1 . ASP B  1 475 ? 5.68114  2.20219   -23.97987 1.000 29.40642 ? 506  ASP B OD1 1 
ATOM   7435 O  OD2 . ASP B  1 475 ? 5.37969  2.93438   -26.02841 1.000 28.47571 ? 506  ASP B OD2 1 
ATOM   7436 N  N   . SER B  1 476 ? 9.16503  -0.96405  -24.97648 1.000 21.47359 ? 507  SER B N   1 
ATOM   7437 C  CA  . SER B  1 476 ? 10.04963 -1.93079  -25.61513 1.000 21.00205 ? 507  SER B CA  1 
ATOM   7438 C  C   . SER B  1 476 ? 9.64318  -2.12421  -27.07434 1.000 24.19721 ? 507  SER B C   1 
ATOM   7439 O  O   . SER B  1 476 ? 8.45135  -2.16843  -27.38220 1.000 23.37202 ? 507  SER B O   1 
ATOM   7440 C  CB  . SER B  1 476 ? 9.99182  -3.28042  -24.89567 1.000 22.86589 ? 507  SER B CB  1 
ATOM   7441 O  OG  . SER B  1 476 ? 10.64957 -4.29420  -25.64927 1.000 22.54432 ? 507  SER B OG  1 
ATOM   7442 N  N   . PRO B  1 477 ? 10.60401 -2.25304  -27.99117 1.000 20.26130 ? 508  PRO B N   1 
ATOM   7443 C  CA  . PRO B  1 477 ? 10.24008 -2.57420  -29.38030 1.000 22.31800 ? 508  PRO B CA  1 
ATOM   7444 C  C   . PRO B  1 477 ? 9.82838  -4.02293  -29.58388 1.000 27.00467 ? 508  PRO B C   1 
ATOM   7445 O  O   . PRO B  1 477 ? 9.39300  -4.36897  -30.69257 1.000 26.99554 ? 508  PRO B O   1 
ATOM   7446 C  CB  . PRO B  1 477 ? 11.51183 -2.23828  -30.17291 1.000 24.72502 ? 508  PRO B CB  1 
ATOM   7447 C  CG  . PRO B  1 477 ? 12.61837 -2.30136  -29.19398 1.000 22.77632 ? 508  PRO B CG  1 
ATOM   7448 C  CD  . PRO B  1 477 ? 12.04935 -2.03047  -27.81909 1.000 23.68808 ? 508  PRO B CD  1 
ATOM   7449 N  N   . TYR B  1 478 ? 9.92401  -4.86731  -28.56128 1.000 22.37979 ? 509  TYR B N   1 
ATOM   7450 C  CA  . TYR B  1 478 ? 9.67510  -6.30488  -28.72087 1.000 22.02478 ? 509  TYR B CA  1 
ATOM   7451 C  C   . TYR B  1 478 ? 8.37339  -6.74150  -28.04712 1.000 27.77476 ? 509  TYR B C   1 
ATOM   7452 O  O   . TYR B  1 478 ? 7.63075  -5.90835  -27.52781 1.000 34.06329 ? 509  TYR B O   1 
ATOM   7453 C  CB  . TYR B  1 478 ? 10.85211 -7.10807  -28.15782 1.000 23.69192 ? 509  TYR B CB  1 
ATOM   7454 C  CG  . TYR B  1 478 ? 12.18861 -6.54483  -28.58116 1.000 25.11746 ? 509  TYR B CG  1 
ATOM   7455 C  CD1 . TYR B  1 478 ? 12.59766 -6.60761  -29.91120 1.000 23.51776 ? 509  TYR B CD1 1 
ATOM   7456 C  CD2 . TYR B  1 478 ? 13.02987 -5.91871  -27.66353 1.000 22.49108 ? 509  TYR B CD2 1 
ATOM   7457 C  CE1 . TYR B  1 478 ? 13.81253 -6.07976  -30.31940 1.000 24.33864 ? 509  TYR B CE1 1 
ATOM   7458 C  CE2 . TYR B  1 478 ? 14.24858 -5.38528  -28.06294 1.000 20.71364 ? 509  TYR B CE2 1 
ATOM   7459 C  CZ  . TYR B  1 478 ? 14.63416 -5.46778  -29.39087 1.000 23.93923 ? 509  TYR B CZ  1 
ATOM   7460 O  OH  . TYR B  1 478 ? 15.83314 -4.93823  -29.80670 1.000 22.10214 ? 509  TYR B OH  1 
HETATM 7461 C  C1  . G4S C  2 .   ? 5.25987  -3.54002  -9.53402  1.000 60.03416 ? 1    G4S G C1  1 
HETATM 7462 C  C2  . G4S C  2 .   ? 6.35235  -3.78461  -10.55662 1.000 55.29074 ? 1    G4S G C2  1 
HETATM 7463 C  C3  . G4S C  2 .   ? 7.32003  -2.61607  -10.62473 1.000 53.35761 ? 1    G4S G C3  1 
HETATM 7464 C  C4  . G4S C  2 .   ? 6.58596  -1.28671  -10.76698 1.000 57.26336 ? 1    G4S G C4  1 
HETATM 7465 C  C5  . G4S C  2 .   ? 5.53442  -1.15252  -9.67057  1.000 60.21262 ? 1    G4S G C5  1 
HETATM 7466 C  C6  . G4S C  2 .   ? 4.70249  0.10602   -9.77135  1.000 66.19748 ? 1    G4S G C6  1 
HETATM 7467 O  O1  . G4S C  2 .   ? 4.31921  -4.56465  -9.62638  1.000 71.70968 ? 1    G4S G O1  1 
HETATM 7468 O  O2  . G4S C  2 .   ? 7.06250  -4.97745  -10.22515 1.000 41.80308 ? 1    G4S G O2  1 
HETATM 7469 O  O3  . G4S C  2 .   ? 8.24315  -2.81015  -11.69668 1.000 47.71572 ? 1    G4S G O3  1 
HETATM 7470 O  O4  . G4S C  2 .   ? 5.85667  -1.26831  -12.05583 1.000 58.82413 ? 1    G4S G O4  1 
HETATM 7471 O  O5  . G4S C  2 .   ? 4.62695  -2.27180  -9.74842  1.000 60.32321 ? 1    G4S G O5  1 
HETATM 7472 O  O6  . G4S C  2 .   ? 5.52119  1.26770   -9.88626  1.000 71.77308 ? 1    G4S G O6  1 
HETATM 7473 S  S   . G4S C  2 .   ? 6.35876  -0.30438  -13.22380 1.000 66.43383 ? 1    G4S G S   1 
HETATM 7474 O  O7  . G4S C  2 .   ? 7.26552  0.62541   -12.58496 1.000 68.24917 ? 1    G4S G O7  1 
HETATM 7475 O  O8  . G4S C  2 .   ? 5.16779  0.33464   -13.74085 1.000 68.73736 ? 1    G4S G O8  1 
HETATM 7476 O  O9  . G4S C  2 .   ? 7.01595  -1.14134  -14.20290 1.000 62.87907 ? 1    G4S G O9  1 
HETATM 7477 C  C1  . DGS C  2 .   ? 9.37349  -1.92810  -11.47877 1.000 46.03059 ? 2    DGS G C1  1 
HETATM 7478 C  C2  . DGS C  2 .   ? 10.13544 -1.86250  -12.79635 1.000 42.77765 ? 2    DGS G C2  1 
HETATM 7479 C  C3  . DGS C  2 .   ? 11.48802 -1.22333  -12.53831 1.000 41.70147 ? 2    DGS G C3  1 
HETATM 7480 C  C4  . DGS C  2 .   ? 12.30588 -2.03238  -11.53580 1.000 37.38590 ? 2    DGS G C4  1 
HETATM 7481 C  C5  . DGS C  2 .   ? 11.46855 -1.73035  -10.30206 1.000 35.82594 ? 2    DGS G C5  1 
HETATM 7482 C  C6  . DGS C  2 .   ? 11.37375 -0.22769  -10.42973 1.000 40.79329 ? 2    DGS G C6  1 
HETATM 7483 O  O2  . DGS C  2 .   ? 10.20232 -3.22925  -13.28557 1.000 41.13155 ? 2    DGS G O2  1 
HETATM 7484 O  O3  . DGS C  2 .   ? 11.33503 0.03868   -11.85505 1.000 43.49456 ? 2    DGS G O3  1 
HETATM 7485 O  O4  . DGS C  2 .   ? 13.62608 -1.53782  -11.43153 1.000 26.85213 ? 2    DGS G O4  1 
HETATM 7486 O  O5  . DGS C  2 .   ? 10.20491 -2.40044  -10.41604 1.000 46.86647 ? 2    DGS G O5  1 
HETATM 7487 O  O7  . DGS C  2 .   ? 12.05965 -3.13311  -14.91482 0.684 36.06333 ? 2    DGS G O7  1 
HETATM 7488 O  O8  . DGS C  2 .   ? 10.54173 -4.99297  -14.87220 0.805 40.74775 ? 2    DGS G O8  1 
HETATM 7489 O  O9  . DGS C  2 .   ? 9.78356  -2.84479  -15.65057 0.794 46.58719 ? 2    DGS G O9  1 
HETATM 7490 S  S   . DGS C  2 .   ? 10.68599 -3.56036  -14.77640 0.520 37.42687 ? 2    DGS G S   1 
HETATM 7491 C  C1  . GAL C  2 .   ? 14.30787 -1.92933  -12.62994 1.000 27.55076 ? 3    GAL G C1  1 
HETATM 7492 C  C2  . GAL C  2 .   ? 15.48423 -0.98798  -12.87768 1.000 26.06413 ? 3    GAL G C2  1 
HETATM 7493 C  C3  . GAL C  2 .   ? 16.29894 -1.45173  -14.07849 1.000 25.31117 ? 3    GAL G C3  1 
HETATM 7494 C  C4  . GAL C  2 .   ? 16.67538 -2.92216  -13.94795 1.000 24.58737 ? 3    GAL G C4  1 
HETATM 7495 C  C5  . GAL C  2 .   ? 15.43335 -3.75906  -13.69443 1.000 21.81297 ? 3    GAL G C5  1 
HETATM 7496 C  C6  . GAL C  2 .   ? 15.72163 -5.22658  -13.47701 1.000 24.19712 ? 3    GAL G C6  1 
HETATM 7497 O  O2  . GAL C  2 .   ? 15.02679 0.35874   -12.97864 1.000 25.46550 ? 3    GAL G O2  1 
HETATM 7498 O  O3  . GAL C  2 .   ? 17.45115 -0.62571  -14.25926 1.000 24.56962 ? 3    GAL G O3  1 
HETATM 7499 O  O4  . GAL C  2 .   ? 17.57289 -3.10979  -12.85048 1.000 24.81012 ? 3    GAL G O4  1 
HETATM 7500 O  O5  . GAL C  2 .   ? 14.78223 -3.27571  -12.50817 1.000 24.76821 ? 3    GAL G O5  1 
HETATM 7501 O  O6  . GAL C  2 .   ? 14.49941 -5.97575  -13.33632 1.000 22.55369 ? 3    GAL G O6  1 
HETATM 7502 C  C1  . DGS C  2 .   ? 17.69621 -0.49233  -15.67572 1.000 25.41430 ? 4    DGS G C1  1 
HETATM 7503 C  C2  . DGS C  2 .   ? 19.04474 0.19257   -15.85346 1.000 19.41676 ? 4    DGS G C2  1 
HETATM 7504 C  C3  . DGS C  2 .   ? 19.17749 0.61204   -17.30624 1.000 19.98098 ? 4    DGS G C3  1 
HETATM 7505 C  C4  . DGS C  2 .   ? 18.08159 1.60289   -17.70310 1.000 24.58096 ? 4    DGS G C4  1 
HETATM 7506 C  C5  . DGS C  2 .   ? 16.90976 0.63420   -17.65233 1.000 25.42945 ? 4    DGS G C5  1 
HETATM 7507 C  C6  . DGS C  2 .   ? 17.48743 -0.48885  -18.48148 1.000 22.86542 ? 4    DGS G C6  1 
HETATM 7508 O  O2  . DGS C  2 .   ? 19.06942 1.30679   -14.92473 1.000 23.01830 ? 4    DGS G O2  1 
HETATM 7509 O  O3  . DGS C  2 .   ? 18.89810 -0.52244  -18.15213 1.000 22.13442 ? 4    DGS G O3  1 
HETATM 7510 O  O4  . DGS C  2 .   ? 18.28600 2.15115   -18.99165 1.000 21.54126 ? 4    DGS G O4  1 
HETATM 7511 O  O5  . DGS C  2 .   ? 16.65273 0.26461   -16.28943 1.000 24.69664 ? 4    DGS G O5  1 
HETATM 7512 O  O7  . DGS C  2 .   ? 21.48307 1.43083   -14.76841 0.757 18.05866 ? 4    DGS G O7  1 
HETATM 7513 O  O8  . DGS C  2 .   ? 20.35953 3.18491   -15.96346 0.971 20.41904 ? 4    DGS G O8  1 
HETATM 7514 O  O9  . DGS C  2 .   ? 20.07981 3.00194   -13.59511 0.857 20.63419 ? 4    DGS G O9  1 
HETATM 7515 S  S   . DGS C  2 .   ? 20.33171 2.28447   -14.83718 0.720 18.22999 ? 4    DGS G S   1 
HETATM 7516 C  C1  . G4S D  2 .   ? 43.31483 30.44113  -14.51890 1.000 71.92614 ? 1    G4S H C1  1 
HETATM 7517 C  C2  . G4S D  2 .   ? 41.97468 30.66174  -15.18986 1.000 66.07668 ? 1    G4S H C2  1 
HETATM 7518 C  C3  . G4S D  2 .   ? 40.99895 29.54056  -14.87134 1.000 64.56105 ? 1    G4S H C3  1 
HETATM 7519 C  C4  . G4S D  2 .   ? 41.62765 28.17595  -15.11607 1.000 65.71481 ? 1    G4S H C4  1 
HETATM 7520 C  C5  . G4S D  2 .   ? 42.93910 28.06509  -14.35711 1.000 73.31098 ? 1    G4S H C5  1 
HETATM 7521 C  C6  . G4S D  2 .   ? 43.65683 26.75844  -14.59911 1.000 76.67509 ? 1    G4S H C6  1 
HETATM 7522 O  O1  . G4S D  2 .   ? 44.20045 31.38974  -15.02319 1.000 80.67647 ? 1    G4S H O1  1 
HETATM 7523 O  O2  . G4S D  2 .   ? 41.42789 31.91051  -14.77355 1.000 51.21906 ? 1    G4S H O2  1 
HETATM 7524 O  O3  . G4S D  2 .   ? 39.79608 29.69814  -15.62416 1.000 59.31553 ? 1    G4S H O3  1 
HETATM 7525 O  O4  . G4S D  2 .   ? 42.04139 28.08660  -16.53425 1.000 68.30289 ? 1    G4S H O4  1 
HETATM 7526 O  O5  . G4S D  2 .   ? 43.81914 29.12645  -14.78857 1.000 75.90463 ? 1    G4S H O5  1 
HETATM 7527 O  O6  . G4S D  2 .   ? 42.75893 25.66271  -14.44563 1.000 81.28707 ? 1    G4S H O6  1 
HETATM 7528 S  S   . G4S D  2 .   ? 41.32952 27.04426  -17.50122 1.000 78.47429 ? 1    G4S H S   1 
HETATM 7529 O  O7  . G4S D  2 .   ? 41.01861 25.90706  -16.66324 1.000 80.34659 ? 1    G4S H O7  1 
HETATM 7530 O  O8  . G4S D  2 .   ? 42.32375 26.74792  -18.51008 1.000 79.63925 ? 1    G4S H O8  1 
HETATM 7531 O  O9  . G4S D  2 .   ? 40.14936 27.68535  -18.04189 1.000 68.79897 ? 1    G4S H O9  1 
HETATM 7532 C  C1  . DGS D  2 .   ? 38.78586 28.78234  -15.12817 1.000 54.63648 ? 2    DGS H C1  1 
HETATM 7533 C  C2  . DGS D  2 .   ? 37.70780 28.71929  -16.20200 1.000 48.55585 ? 2    DGS H C2  1 
HETATM 7534 C  C3  . DGS D  2 .   ? 36.46116 28.08037  -15.61620 1.000 42.72330 ? 2    DGS H C3  1 
HETATM 7535 C  C4  . DGS D  2 .   ? 35.93971 28.85760  -14.41444 1.000 42.87170 ? 2    DGS H C4  1 
HETATM 7536 C  C5  . DGS D  2 .   ? 37.07129 28.52696  -13.45305 1.000 39.36449 ? 2    DGS H C5  1 
HETATM 7537 C  C6  . DGS D  2 .   ? 37.13208 27.02930  -13.64528 1.000 43.46315 ? 2    DGS H C6  1 
HETATM 7538 O  O2  . DGS D  2 .   ? 37.48600 30.08457  -16.65741 1.000 50.69815 ? 2    DGS H O2  1 
HETATM 7539 O  O3  . DGS D  2 .   ? 36.74805 26.79728  -15.02451 1.000 52.35509 ? 2    DGS H O3  1 
HETATM 7540 O  O4  . DGS D  2 .   ? 34.70260 28.31923  -13.99441 1.000 28.83115 ? 2    DGS H O4  1 
HETATM 7541 O  O5  . DGS D  2 .   ? 38.26118 29.21077  -13.87055 1.000 50.52311 ? 2    DGS H O5  1 
HETATM 7542 O  O7  . DGS D  2 .   ? 36.74488 31.83188  -18.13572 0.696 45.17990 ? 2    DGS H O7  1 
HETATM 7543 O  O8  . DGS D  2 .   ? 37.54373 29.75651  -19.06023 0.741 54.07334 ? 2    DGS H O8  1 
HETATM 7544 O  O9  . DGS D  2 .   ? 35.40048 29.84429  -17.96259 0.647 42.86747 ? 2    DGS H O9  1 
HETATM 7545 S  S   . DGS D  2 .   ? 36.73632 30.39074  -18.04010 0.411 43.02142 ? 2    DGS H S   1 
HETATM 7546 C  C1  . GAL D  2 .   ? 33.75083 28.71032  -14.99326 1.000 29.16597 ? 3    GAL H C1  1 
HETATM 7547 C  C2  . GAL D  2 .   ? 32.53023 27.79847  -14.96028 1.000 27.33312 ? 3    GAL H C2  1 
HETATM 7548 C  C3  . GAL D  2 .   ? 31.44549 28.30299  -15.89891 1.000 25.84953 ? 3    GAL H C3  1 
HETATM 7549 C  C4  . GAL D  2 .   ? 31.14462 29.77023  -15.63767 1.000 26.29354 ? 3    GAL H C4  1 
HETATM 7550 C  C5  . GAL D  2 .   ? 32.42843 30.58042  -15.70360 1.000 24.58615 ? 3    GAL H C5  1 
HETATM 7551 C  C6  . GAL D  2 .   ? 32.23785 32.04305  -15.37390 1.000 25.17255 ? 3    GAL H C6  1 
HETATM 7552 O  O2  . GAL D  2 .   ? 32.89777 26.45428  -15.25472 1.000 27.27896 ? 3    GAL H O2  1 
HETATM 7553 O  O3  . GAL D  2 .   ? 30.27965 27.47883  -15.80061 1.000 27.17518 ? 3    GAL H O3  1 
HETATM 7554 O  O4  . GAL D  2 .   ? 30.60698 29.92209  -14.32763 1.000 26.31202 ? 3    GAL H O4  1 
HETATM 7555 O  O5  . GAL D  2 .   ? 33.35765 30.06141  -14.73919 1.000 27.06300 ? 3    GAL H O5  1 
HETATM 7556 O  O6  . GAL D  2 .   ? 33.44588 32.77862  -15.59630 1.000 23.24896 ? 3    GAL H O6  1 
HETATM 7557 C  C1  . DGS D  2 .   ? 29.68879 27.35779  -17.11567 1.000 25.73389 ? 4    DGS H C1  1 
HETATM 7558 C  C2  . DGS D  2 .   ? 28.33919 26.67162  -16.94026 1.000 22.66593 ? 4    DGS H C2  1 
HETATM 7559 C  C3  . DGS D  2 .   ? 27.83043 26.26424  -18.30717 1.000 22.06863 ? 4    DGS H C3  1 
HETATM 7560 C  C4  . DGS D  2 .   ? 28.77991 25.28157  -18.98628 1.000 22.08750 ? 4    DGS H C4  1 
HETATM 7561 C  C5  . DGS D  2 .   ? 29.92177 26.25506  -19.24256 1.000 25.32518 ? 4    DGS H C5  1 
HETATM 7562 C  C6  . DGS D  2 .   ? 29.14872 27.39184  -19.87059 1.000 22.23720 ? 4    DGS H C6  1 
HETATM 7563 O  O2  . DGS D  2 .   ? 28.55929 25.54475  -16.05826 1.000 23.04267 ? 4    DGS H O2  1 
HETATM 7564 O  O3  . DGS D  2 .   ? 27.85768 27.39008  -19.20746 1.000 24.25916 ? 4    DGS H O3  1 
HETATM 7565 O  O4  . DGS D  2 .   ? 28.22024 24.76933  -20.17916 1.000 22.23357 ? 4    DGS H O4  1 
HETATM 7566 O  O5  . DGS D  2 .   ? 30.53147 26.60748  -17.99246 1.000 25.13958 ? 4    DGS H O5  1 
HETATM 7567 O  O7  . DGS D  2 .   ? 26.27223 25.45566  -15.24271 0.703 19.43254 ? 4    DGS H O7  1 
HETATM 7568 O  O8  . DGS D  2 .   ? 27.01400 23.71558  -16.72378 0.962 20.33852 ? 4    DGS H O8  1 
HETATM 7569 O  O9  . DGS D  2 .   ? 27.92707 23.86316  -14.51394 0.813 20.22267 ? 4    DGS H O9  1 
HETATM 7570 S  S   . DGS D  2 .   ? 27.35335 24.58788  -15.62421 0.795 19.37662 ? 4    DGS H S   1 
HETATM 7571 CA CA  . CA  E  3 .   ? 22.39122 -4.54846  -10.56651 1.000 23.75459 ? 601  CA  A CA  1 
HETATM 7572 BR BR  . BR  F  4 .   ? 27.86624 -22.04712 -21.90025 0.837 24.22599 ? 602  BR  A BR  1 
HETATM 7573 BR BR  . BR  G  4 .   ? 8.50488  -19.70624 -5.44434  0.720 25.71303 ? 603  BR  A BR  1 
HETATM 7574 BR BR  . BR  H  4 .   ? 38.52104 -25.97099 6.88904   0.620 29.54677 ? 604  BR  A BR  1 
HETATM 7575 CL CL  . CL  I  5 .   ? 29.51302 16.92708  -12.13743 1.000 28.40437 ? 605  CL  A CL  1 
HETATM 7576 CL CL  . CL  J  5 .   ? 19.09494 9.92794   -10.84748 1.000 28.22655 ? 606  CL  A CL  1 
HETATM 7577 CL CL  . CL  K  5 .   ? 37.04462 17.71009  -32.06544 1.000 25.42306 ? 607  CL  A CL  1 
HETATM 7578 CL CL  . CL  L  5 .   ? 28.46862 -6.46745  -35.79664 1.000 36.30981 ? 608  CL  A CL  1 
HETATM 7579 CL CL  . CL  M  5 .   ? 50.28327 15.82415  -20.56096 1.000 36.27384 ? 609  CL  A CL  1 
HETATM 7580 CL CL  . CL  N  5 .   ? 15.65216 5.17245   -10.40310 1.000 33.88963 ? 610  CL  A CL  1 
HETATM 7581 C  C1  . GOL O  6 .   ? 20.90841 -2.55930  -32.98471 1.000 31.39013 ? 611  GOL A C1  1 
HETATM 7582 O  O1  . GOL O  6 .   ? 21.86044 -3.50775  -33.36518 1.000 37.03537 ? 611  GOL A O1  1 
HETATM 7583 C  C2  . GOL O  6 .   ? 19.52968 -3.16509  -33.31621 1.000 34.83222 ? 611  GOL A C2  1 
HETATM 7584 O  O2  . GOL O  6 .   ? 19.52125 -3.75695  -34.56456 1.000 42.79902 ? 611  GOL A O2  1 
HETATM 7585 C  C3  . GOL O  6 .   ? 18.55152 -1.98278  -33.25956 1.000 34.96525 ? 611  GOL A C3  1 
HETATM 7586 O  O3  . GOL O  6 .   ? 17.28651 -2.50841  -33.55046 1.000 37.58421 ? 611  GOL A O3  1 
HETATM 7587 C  C1  . GOL P  6 .   ? 29.07090 7.16032   4.05502   1.000 37.92213 ? 612  GOL A C1  1 
HETATM 7588 O  O1  . GOL P  6 .   ? 30.10241 8.02196   4.41666   1.000 46.54621 ? 612  GOL A O1  1 
HETATM 7589 C  C2  . GOL P  6 .   ? 28.90483 6.17710   5.23879   1.000 35.11803 ? 612  GOL A C2  1 
HETATM 7590 O  O2  . GOL P  6 .   ? 28.64265 6.84570   6.43186   1.000 42.38034 ? 612  GOL A O2  1 
HETATM 7591 C  C3  . GOL P  6 .   ? 27.73029 5.26218   4.84361   1.000 32.98055 ? 612  GOL A C3  1 
HETATM 7592 O  O3  . GOL P  6 .   ? 27.47199 4.50331   5.98241   1.000 33.55799 ? 612  GOL A O3  1 
HETATM 7593 C  C1  . GOL Q  6 .   ? 22.86515 10.24818  -14.75371 1.000 27.92339 ? 613  GOL A C1  1 
HETATM 7594 O  O1  . GOL Q  6 .   ? 22.29190 9.51337   -13.71253 1.000 30.19423 ? 613  GOL A O1  1 
HETATM 7595 C  C2  . GOL Q  6 .   ? 21.75332 10.94954  -15.57825 1.000 40.69378 ? 613  GOL A C2  1 
HETATM 7596 O  O2  . GOL Q  6 .   ? 22.14644 11.19507  -16.90135 1.000 40.43683 ? 613  GOL A O2  1 
HETATM 7597 C  C3  . GOL Q  6 .   ? 20.49347 10.06755  -15.47450 1.000 38.52916 ? 613  GOL A C3  1 
HETATM 7598 O  O3  . GOL Q  6 .   ? 19.42315 10.94000  -15.75876 1.000 40.54636 ? 613  GOL A O3  1 
HETATM 7599 CA CA  . CA  R  3 .   ? 26.54716 31.37894  -10.91349 1.000 24.95606 ? 601  CA  B CA  1 
HETATM 7600 BR BR  . BR  S  4 .   ? 18.39111 48.96598  -20.33383 0.745 22.37830 ? 602  BR  B BR  1 
HETATM 7601 BR BR  . BR  T  4 .   ? 41.41596 46.40819  -9.49741  0.693 25.74261 ? 603  BR  B BR  1 
HETATM 7602 BR BR  . BR  U  4 .   ? 15.65834 52.65725  10.22147  0.524 30.42010 ? 604  BR  B BR  1 
HETATM 7603 CL CL  . CL  V  5 .   ? 6.79226  9.32821   -28.19055 1.000 25.99393 ? 605  CL  B CL  1 
HETATM 7604 CL CL  . CL  W  5 .   ? -3.95355 13.03365  -11.71394 1.000 30.30938 ? 606  CL  B CL  1 
HETATM 7605 CL CL  . CL  X  5 .   ? 33.10866 21.53877  -12.53787 1.000 31.39607 ? 607  CL  B CL  1 
HETATM 7606 C  C1  . GOL Y  6 .   ? 22.12873 29.57848  -33.37498 1.000 39.67516 ? 608  GOL B C1  1 
HETATM 7607 O  O1  . GOL Y  6 .   ? 21.22795 30.61844  -33.14808 1.000 40.36556 ? 608  GOL B O1  1 
HETATM 7608 C  C2  . GOL Y  6 .   ? 23.42040 30.23533  -33.87575 1.000 40.15926 ? 608  GOL B C2  1 
HETATM 7609 O  O2  . GOL Y  6 .   ? 23.91215 31.15851  -32.95707 1.000 43.36001 ? 608  GOL B O2  1 
HETATM 7610 C  C3  . GOL Y  6 .   ? 24.38794 29.05945  -34.10920 1.000 37.50972 ? 608  GOL B C3  1 
HETATM 7611 O  O3  . GOL Y  6 .   ? 25.64010 29.61340  -34.38281 1.000 44.77000 ? 608  GOL B O3  1 
HETATM 7612 C  C1  . GOL Z  6 .   ? 24.99155 16.45113  -15.09810 1.000 26.63072 ? 609  GOL B C1  1 
HETATM 7613 O  O1  . GOL Z  6 .   ? 25.50756 17.30799  -14.11751 1.000 27.03102 ? 609  GOL B O1  1 
HETATM 7614 C  C2  . GOL Z  6 .   ? 25.97157 16.53539  -16.31230 1.000 35.68974 ? 609  GOL B C2  1 
HETATM 7615 O  O2  . GOL Z  6 .   ? 27.16909 15.86250  -16.07341 1.000 44.74748 ? 609  GOL B O2  1 
HETATM 7616 C  C3  . GOL Z  6 .   ? 25.22294 15.93339  -17.52866 1.000 30.69132 ? 609  GOL B C3  1 
HETATM 7617 O  O3  . GOL Z  6 .   ? 24.16749 15.14601  -17.06411 1.000 34.11796 ? 609  GOL B O3  1 
HETATM 7618 C  C1  . GOL AA 6 .   ? 23.58977 19.47202  4.77801   1.000 35.72117 ? 610  GOL B C1  1 
HETATM 7619 O  O1  . GOL AA 6 .   ? 24.43671 18.35213  4.65768   1.000 46.34707 ? 610  GOL B O1  1 
HETATM 7620 C  C2  . GOL AA 6 .   ? 24.17823 20.36675  5.88686   1.000 36.08404 ? 610  GOL B C2  1 
HETATM 7621 O  O2  . GOL AA 6 .   ? 24.75974 19.61656  6.90150   1.000 39.01991 ? 610  GOL B O2  1 
HETATM 7622 C  C3  . GOL AA 6 .   ? 25.20574 21.27895  5.17348   1.000 27.18569 ? 610  GOL B C3  1 
HETATM 7623 O  O3  . GOL AA 6 .   ? 25.79571 22.02742  6.17522   1.000 30.84064 ? 610  GOL B O3  1 
HETATM 7624 O  O   . HOH BA 7 .   ? 34.72459 -15.16789 9.04255   1.000 34.33649 ? 701  HOH A O   1 
HETATM 7625 O  O   . HOH BA 7 .   ? 46.09677 15.36327  -8.50432  1.000 39.03726 ? 702  HOH A O   1 
HETATM 7626 O  O   . HOH BA 7 .   ? 21.71706 -24.24616 -7.14846  1.000 22.56015 ? 703  HOH A O   1 
HETATM 7627 O  O   . HOH BA 7 .   ? 42.32905 -9.73643  10.40584  1.000 36.60113 ? 704  HOH A O   1 
HETATM 7628 O  O   . HOH BA 7 .   ? 27.010   -29.275   8.898     1.000 51.76033 ? 705  HOH A O   1 
HETATM 7629 O  O   . HOH BA 7 .   ? 28.58363 -34.47612 -9.07454  1.000 37.62813 ? 706  HOH A O   1 
HETATM 7630 O  O   . HOH BA 7 .   ? 16.76164 -2.77593  -36.01488 1.000 42.86232 ? 707  HOH A O   1 
HETATM 7631 O  O   . HOH BA 7 .   ? 37.30047 3.14280   -16.09573 1.000 25.84671 ? 708  HOH A O   1 
HETATM 7632 O  O   . HOH BA 7 .   ? 48.45138 1.65886   -2.22384  1.000 39.22873 ? 709  HOH A O   1 
HETATM 7633 O  O   . HOH BA 7 .   ? 42.90717 -1.05467  -24.80593 1.000 37.25811 ? 710  HOH A O   1 
HETATM 7634 O  O   . HOH BA 7 .   ? 36.70985 -26.54895 9.73851   1.000 40.94233 ? 711  HOH A O   1 
HETATM 7635 O  O   A HOH BA 7 .   ? 16.97230 10.69967  -15.20957 0.402 19.15235 ? 712  HOH A O   1 
HETATM 7636 O  O   B HOH BA 7 .   ? 16.98374 9.90872   -14.67075 0.598 19.19147 ? 712  HOH A O   1 
HETATM 7637 O  O   . HOH BA 7 .   ? 1.55576  -8.80775  -12.07533 1.000 34.14941 ? 713  HOH A O   1 
HETATM 7638 O  O   . HOH BA 7 .   ? 18.00671 8.47409   8.27954   1.000 40.33474 ? 714  HOH A O   1 
HETATM 7639 O  O   . HOH BA 7 .   ? 34.10191 -29.49186 -2.08293  1.000 32.10032 ? 715  HOH A O   1 
HETATM 7640 O  O   . HOH BA 7 .   ? 29.46622 22.42338  -20.67568 1.000 24.91822 ? 716  HOH A O   1 
HETATM 7641 O  O   . HOH BA 7 .   ? 10.06961 -16.81678 -17.15834 1.000 39.97194 ? 717  HOH A O   1 
HETATM 7642 O  O   . HOH BA 7 .   ? 2.43705  -9.09657  -4.45839  1.000 40.89145 ? 718  HOH A O   1 
HETATM 7643 O  O   . HOH BA 7 .   ? 12.01066 -24.12732 -1.93076  1.000 30.48745 ? 719  HOH A O   1 
HETATM 7644 O  O   . HOH BA 7 .   ? 37.83470 0.50867   -0.30861  1.000 31.30066 ? 720  HOH A O   1 
HETATM 7645 O  O   . HOH BA 7 .   ? 49.15015 -10.04663 -14.68123 1.000 45.13683 ? 721  HOH A O   1 
HETATM 7646 O  O   . HOH BA 7 .   ? 31.21098 -19.73241 11.92049  1.000 40.30826 ? 722  HOH A O   1 
HETATM 7647 O  O   . HOH BA 7 .   ? 27.31381 -16.16706 -31.72186 1.000 45.19947 ? 723  HOH A O   1 
HETATM 7648 O  O   . HOH BA 7 .   ? 47.92330 -6.11135  -1.53607  1.000 34.56578 ? 724  HOH A O   1 
HETATM 7649 O  O   . HOH BA 7 .   ? 23.89275 -17.36728 -30.93476 1.000 44.96166 ? 725  HOH A O   1 
HETATM 7650 O  O   . HOH BA 7 .   ? 13.53155 3.23211   -37.11939 1.000 37.23511 ? 726  HOH A O   1 
HETATM 7651 O  O   . HOH BA 7 .   ? 51.95684 -8.29413  -13.19539 1.000 39.82586 ? 727  HOH A O   1 
HETATM 7652 O  O   . HOH BA 7 .   ? 33.48478 -4.51766  10.91846  1.000 39.46859 ? 728  HOH A O   1 
HETATM 7653 O  O   . HOH BA 7 .   ? 29.90714 15.18525  -34.88457 1.000 42.73201 ? 729  HOH A O   1 
HETATM 7654 O  O   . HOH BA 7 .   ? 26.82993 31.85705  -33.51193 1.000 42.20761 ? 730  HOH A O   1 
HETATM 7655 O  O   . HOH BA 7 .   ? 12.22481 -10.96970 -13.05779 1.000 26.62149 ? 731  HOH A O   1 
HETATM 7656 O  O   . HOH BA 7 .   ? 24.61863 10.91010  -33.06701 1.000 33.46255 ? 732  HOH A O   1 
HETATM 7657 O  O   . HOH BA 7 .   ? 46.27975 -23.50680 -13.95544 1.000 39.58422 ? 733  HOH A O   1 
HETATM 7658 O  O   . HOH BA 7 .   ? 49.35256 10.11932  -9.06274  1.000 30.89248 ? 734  HOH A O   1 
HETATM 7659 O  O   . HOH BA 7 .   ? 9.58888  3.61324   -34.26216 1.000 36.93306 ? 735  HOH A O   1 
HETATM 7660 O  O   . HOH BA 7 .   ? 21.96487 6.34737   8.38573   1.000 30.83506 ? 736  HOH A O   1 
HETATM 7661 O  O   . HOH BA 7 .   ? 12.45788 0.01018   -17.58788 1.000 36.34216 ? 737  HOH A O   1 
HETATM 7662 O  O   . HOH BA 7 .   ? 16.69625 -24.29276 -29.74536 1.000 44.59560 ? 738  HOH A O   1 
HETATM 7663 O  O   . HOH BA 7 .   ? 48.80957 -9.08185  -18.60074 1.000 48.18051 ? 739  HOH A O   1 
HETATM 7664 O  O   . HOH BA 7 .   ? 8.19645  7.15802   -33.45113 1.000 41.85190 ? 740  HOH A O   1 
HETATM 7665 O  O   . HOH BA 7 .   ? 17.98148 2.52140   -23.38352 1.000 19.36284 ? 741  HOH A O   1 
HETATM 7666 O  O   . HOH BA 7 .   ? 20.71201 3.85381   -26.04146 1.000 22.61069 ? 742  HOH A O   1 
HETATM 7667 O  O   . HOH BA 7 .   ? 16.27465 -22.29561 6.17472   1.000 30.71587 ? 743  HOH A O   1 
HETATM 7668 O  O   . HOH BA 7 .   ? 38.37446 -1.69219  5.58342   1.000 31.02546 ? 744  HOH A O   1 
HETATM 7669 O  O   . HOH BA 7 .   ? 10.65216 -14.52831 -11.96994 1.000 34.27345 ? 745  HOH A O   1 
HETATM 7670 O  O   . HOH BA 7 .   ? 30.79323 -7.16532  -14.76157 1.000 16.92049 ? 746  HOH A O   1 
HETATM 7671 O  O   . HOH BA 7 .   ? 15.41974 -8.31595  5.74188   1.000 21.13483 ? 747  HOH A O   1 
HETATM 7672 O  O   . HOH BA 7 .   ? 8.42383  -7.62069  -13.95000 1.000 38.13707 ? 748  HOH A O   1 
HETATM 7673 O  O   . HOH BA 7 .   ? 24.80419 11.03826  -11.58785 1.000 23.47586 ? 749  HOH A O   1 
HETATM 7674 O  O   . HOH BA 7 .   ? 23.85373 2.41705   -36.20332 1.000 22.27356 ? 750  HOH A O   1 
HETATM 7675 O  O   . HOH BA 7 .   ? 23.20862 -10.88034 -7.83748  1.000 16.07878 ? 751  HOH A O   1 
HETATM 7676 O  O   . HOH BA 7 .   ? 16.48090 -27.22370 -16.62650 1.000 30.39155 ? 752  HOH A O   1 
HETATM 7677 O  O   . HOH BA 7 .   ? 35.16974 -1.55533  -16.17871 1.000 18.10108 ? 753  HOH A O   1 
HETATM 7678 O  O   . HOH BA 7 .   ? 34.95321 -16.10178 -27.32370 1.000 26.57687 ? 754  HOH A O   1 
HETATM 7679 O  O   . HOH BA 7 .   ? 36.30629 -3.95019  -16.78312 1.000 19.69239 ? 755  HOH A O   1 
HETATM 7680 O  O   . HOH BA 7 .   ? 52.36115 1.92780   -11.97941 1.000 37.51249 ? 756  HOH A O   1 
HETATM 7681 O  O   . HOH BA 7 .   ? 50.94442 -13.31579 -0.37917  1.000 35.69518 ? 757  HOH A O   1 
HETATM 7682 O  O   . HOH BA 7 .   ? 35.88702 -33.78390 -9.92843  1.000 37.03555 ? 758  HOH A O   1 
HETATM 7683 O  O   . HOH BA 7 .   ? 45.20839 -16.55279 5.32095   1.000 28.62364 ? 759  HOH A O   1 
HETATM 7684 O  O   . HOH BA 7 .   ? 48.83641 2.39003   -10.75937 1.000 28.46514 ? 760  HOH A O   1 
HETATM 7685 O  O   . HOH BA 7 .   ? 40.77900 -8.44244  -25.33874 1.000 39.70487 ? 761  HOH A O   1 
HETATM 7686 O  O   . HOH BA 7 .   ? 18.42853 -11.66577 -2.26814  1.000 17.41790 ? 762  HOH A O   1 
HETATM 7687 O  O   . HOH BA 7 .   ? 17.65349 -9.06737  1.48724   1.000 16.78629 ? 763  HOH A O   1 
HETATM 7688 O  O   . HOH BA 7 .   ? 42.08811 -21.09187 -28.80720 1.000 45.00642 ? 764  HOH A O   1 
HETATM 7689 O  O   . HOH BA 7 .   ? 41.64435 -13.76496 12.20375  1.000 50.03174 ? 765  HOH A O   1 
HETATM 7690 O  O   . HOH BA 7 .   ? 46.84021 -0.61258  -12.84701 1.000 22.59326 ? 766  HOH A O   1 
HETATM 7691 O  O   . HOH BA 7 .   ? 16.69787 -19.09772 6.99554   1.000 29.15128 ? 767  HOH A O   1 
HETATM 7692 O  O   . HOH BA 7 .   ? 16.99677 -7.80121  -8.79537  1.000 18.89101 ? 768  HOH A O   1 
HETATM 7693 O  O   . HOH BA 7 .   ? 53.26331 -1.17550  -9.95256  1.000 22.18400 ? 769  HOH A O   1 
HETATM 7694 O  O   . HOH BA 7 .   ? 28.53300 -1.13643  -31.80578 1.000 21.50704 ? 770  HOH A O   1 
HETATM 7695 O  O   . HOH BA 7 .   ? 33.48515 4.18473   0.92263   1.000 26.03926 ? 771  HOH A O   1 
HETATM 7696 O  O   . HOH BA 7 .   ? 29.84509 -3.68131  9.61754   1.000 21.79973 ? 772  HOH A O   1 
HETATM 7697 O  O   . HOH BA 7 .   ? 24.85834 -10.68704 10.04253  1.000 25.10021 ? 773  HOH A O   1 
HETATM 7698 O  O   . HOH BA 7 .   ? 14.69779 -14.01851 -22.81101 1.000 21.73621 ? 774  HOH A O   1 
HETATM 7699 O  O   . HOH BA 7 .   ? 36.59143 -1.21941  -4.98593  1.000 16.94078 ? 775  HOH A O   1 
HETATM 7700 O  O   . HOH BA 7 .   ? 33.23525 12.71218  -3.33112  1.000 34.79645 ? 776  HOH A O   1 
HETATM 7701 O  O   . HOH BA 7 .   ? 42.69144 1.89232   -4.96794  1.000 23.85721 ? 777  HOH A O   1 
HETATM 7702 O  O   . HOH BA 7 .   ? 15.20496 -6.01432  -17.14328 1.000 23.71270 ? 778  HOH A O   1 
HETATM 7703 O  O   . HOH BA 7 .   ? 33.07985 35.22819  -27.29857 1.000 31.56681 ? 779  HOH A O   1 
HETATM 7704 O  O   . HOH BA 7 .   ? 42.76862 19.18228  -23.24515 1.000 40.48959 ? 780  HOH A O   1 
HETATM 7705 O  O   . HOH BA 7 .   ? 44.14938 15.01350  -3.24094  1.000 23.62450 ? 781  HOH A O   1 
HETATM 7706 O  O   . HOH BA 7 .   ? 17.09473 -25.21758 -26.10375 1.000 33.20147 ? 782  HOH A O   1 
HETATM 7707 O  O   . HOH BA 7 .   ? 31.41142 -31.56264 -13.41356 1.000 29.61224 ? 783  HOH A O   1 
HETATM 7708 O  O   . HOH BA 7 .   ? 48.66981 -10.47794 7.36163   1.000 42.20138 ? 784  HOH A O   1 
HETATM 7709 O  O   . HOH BA 7 .   ? 33.11970 1.13072   8.34041   1.000 33.72687 ? 785  HOH A O   1 
HETATM 7710 O  O   . HOH BA 7 .   ? 15.66445 -5.23149  -24.22853 1.000 20.21290 ? 786  HOH A O   1 
HETATM 7711 O  O   . HOH BA 7 .   ? 36.39323 11.10742  -33.20817 1.000 38.68680 ? 787  HOH A O   1 
HETATM 7712 O  O   . HOH BA 7 .   ? 49.46064 -8.17291  -16.42435 1.000 39.47940 ? 788  HOH A O   1 
HETATM 7713 O  O   . HOH BA 7 .   ? 12.87797 -23.06463 -16.72090 1.000 32.05063 ? 789  HOH A O   1 
HETATM 7714 O  O   . HOH BA 7 .   ? 43.47889 -30.99011 -12.43278 1.000 46.82000 ? 790  HOH A O   1 
HETATM 7715 O  O   . HOH BA 7 .   ? 47.56267 8.07555   -18.55128 1.000 32.85354 ? 791  HOH A O   1 
HETATM 7716 O  O   . HOH BA 7 .   ? 31.71437 30.95958  -27.14573 1.000 23.54482 ? 792  HOH A O   1 
HETATM 7717 O  O   . HOH BA 7 .   ? 18.03698 4.99666   -41.44118 1.000 26.69530 ? 793  HOH A O   1 
HETATM 7718 O  O   . HOH BA 7 .   ? 49.94630 -4.79907  -17.75734 1.000 35.30353 ? 794  HOH A O   1 
HETATM 7719 O  O   . HOH BA 7 .   ? 19.85435 -26.04225 -4.68358  1.000 32.19312 ? 795  HOH A O   1 
HETATM 7720 O  O   . HOH BA 7 .   ? 33.78361 9.37735   -8.44200  1.000 14.69379 ? 796  HOH A O   1 
HETATM 7721 O  O   . HOH BA 7 .   ? 32.69267 6.08841   4.95578   1.000 38.57737 ? 797  HOH A O   1 
HETATM 7722 O  O   . HOH BA 7 .   ? 44.40851 -24.94435 -3.20205  1.000 39.53910 ? 798  HOH A O   1 
HETATM 7723 O  O   . HOH BA 7 .   ? 48.53399 -12.75101 -12.00918 1.000 27.71503 ? 799  HOH A O   1 
HETATM 7724 O  O   . HOH BA 7 .   ? 40.18557 -2.54027  -31.33064 1.000 37.47277 ? 800  HOH A O   1 
HETATM 7725 O  O   . HOH BA 7 .   ? 37.30748 -27.36786 -18.79048 1.000 28.36487 ? 801  HOH A O   1 
HETATM 7726 O  O   . HOH BA 7 .   ? 26.06735 -8.71209  -32.63330 1.000 30.86369 ? 802  HOH A O   1 
HETATM 7727 O  O   . HOH BA 7 .   ? 39.90014 -3.81239  -19.67034 1.000 21.41923 ? 803  HOH A O   1 
HETATM 7728 O  O   . HOH BA 7 .   ? 26.15414 21.80067  -22.08896 1.000 20.71004 ? 804  HOH A O   1 
HETATM 7729 O  O   . HOH BA 7 .   ? 7.07383  -9.48988  -1.63124  1.000 25.64511 ? 805  HOH A O   1 
HETATM 7730 O  O   . HOH BA 7 .   ? 40.99170 20.48076  -25.96325 1.000 39.15837 ? 806  HOH A O   1 
HETATM 7731 O  O   . HOH BA 7 .   ? 11.47398 -19.98818 -14.56316 1.000 31.27621 ? 807  HOH A O   1 
HETATM 7732 O  O   A HOH BA 7 .   ? 34.32482 -26.16335 -21.99259 0.635 25.79843 ? 808  HOH A O   1 
HETATM 7733 O  O   B HOH BA 7 .   ? 35.64194 -26.30577 -21.78262 0.365 28.34792 ? 808  HOH A O   1 
HETATM 7734 O  O   . HOH BA 7 .   ? 17.74992 -1.12438  -6.99828  1.000 17.60261 ? 809  HOH A O   1 
HETATM 7735 O  O   . HOH BA 7 .   ? 39.74918 -6.15597  -18.40930 1.000 22.66102 ? 810  HOH A O   1 
HETATM 7736 O  O   . HOH BA 7 .   ? 20.88893 5.10758   -10.62989 1.000 24.42607 ? 811  HOH A O   1 
HETATM 7737 O  O   . HOH BA 7 .   ? 29.50008 -9.95346  -22.22147 1.000 20.58784 ? 812  HOH A O   1 
HETATM 7738 O  O   . HOH BA 7 .   ? 41.62800 15.25217  -10.74025 1.000 18.66431 ? 813  HOH A O   1 
HETATM 7739 O  O   . HOH BA 7 .   ? 32.44237 24.04887  -23.37593 1.000 24.15951 ? 814  HOH A O   1 
HETATM 7740 O  O   . HOH BA 7 .   ? 22.66071 6.39610   -14.42409 1.000 18.41350 ? 815  HOH A O   1 
HETATM 7741 O  O   . HOH BA 7 .   ? 10.38989 -13.94551 -19.59098 1.000 26.45622 ? 816  HOH A O   1 
HETATM 7742 O  O   . HOH BA 7 .   ? 50.29464 14.00243  -16.72132 1.000 45.16308 ? 817  HOH A O   1 
HETATM 7743 O  O   . HOH BA 7 .   ? 16.55517 -19.54086 -19.67178 1.000 22.68752 ? 818  HOH A O   1 
HETATM 7744 O  O   . HOH BA 7 .   ? 43.01587 0.53014   -15.13088 1.000 29.27932 ? 819  HOH A O   1 
HETATM 7745 O  O   . HOH BA 7 .   ? 20.85130 0.35392   -4.93225  1.000 16.43584 ? 820  HOH A O   1 
HETATM 7746 O  O   . HOH BA 7 .   ? 33.15280 -10.30012 -30.65550 1.000 37.81789 ? 821  HOH A O   1 
HETATM 7747 O  O   . HOH BA 7 .   ? 9.00599  -25.84158 -0.00879  1.000 43.38234 ? 822  HOH A O   1 
HETATM 7748 O  O   . HOH BA 7 .   ? 38.10481 -12.42989 -19.01287 1.000 17.68301 ? 823  HOH A O   1 
HETATM 7749 O  O   A HOH BA 7 .   ? 40.78672 21.52692  -17.02435 0.509 28.77965 ? 824  HOH A O   1 
HETATM 7750 O  O   B HOH BA 7 .   ? 42.28066 21.67325  -16.35832 0.491 29.26950 ? 824  HOH A O   1 
HETATM 7751 O  O   . HOH BA 7 .   ? 13.21802 -3.93249  -24.79481 1.000 22.08616 ? 825  HOH A O   1 
HETATM 7752 O  O   . HOH BA 7 .   ? 33.07716 -8.47829  11.95982  1.000 29.23006 ? 826  HOH A O   1 
HETATM 7753 O  O   . HOH BA 7 .   ? 28.60083 11.27920  -22.08528 1.000 16.84951 ? 827  HOH A O   1 
HETATM 7754 O  O   . HOH BA 7 .   ? 24.60193 -15.58670 10.37661  1.000 31.01773 ? 828  HOH A O   1 
HETATM 7755 O  O   . HOH BA 7 .   ? 27.44205 9.06951   -5.23997  1.000 17.45119 ? 829  HOH A O   1 
HETATM 7756 O  O   . HOH BA 7 .   ? 42.18015 5.64015   -31.84362 1.000 35.68148 ? 830  HOH A O   1 
HETATM 7757 O  O   . HOH BA 7 .   ? 36.43806 -4.01998  8.00131   1.000 41.30719 ? 831  HOH A O   1 
HETATM 7758 O  O   . HOH BA 7 .   ? 20.31448 6.82548   -0.71715  1.000 32.83753 ? 832  HOH A O   1 
HETATM 7759 O  O   . HOH BA 7 .   ? 19.92082 -14.78545 4.49594   1.000 19.69230 ? 833  HOH A O   1 
HETATM 7760 O  O   . HOH BA 7 .   ? 14.26758 -12.05429 -18.88558 1.000 23.64180 ? 834  HOH A O   1 
HETATM 7761 O  O   . HOH BA 7 .   ? 35.59547 -9.11259  12.11167  1.000 37.98137 ? 835  HOH A O   1 
HETATM 7762 O  O   . HOH BA 7 .   ? 29.10612 10.52406  -26.32362 1.000 21.19147 ? 836  HOH A O   1 
HETATM 7763 O  O   . HOH BA 7 .   ? 46.19642 -3.14217  -11.91044 1.000 17.46266 ? 837  HOH A O   1 
HETATM 7764 O  O   . HOH BA 7 .   ? 39.68716 13.18780  -30.70346 1.000 42.31821 ? 838  HOH A O   1 
HETATM 7765 O  O   . HOH BA 7 .   ? 13.48543 -16.91956 6.82460   1.000 31.52390 ? 839  HOH A O   1 
HETATM 7766 O  O   . HOH BA 7 .   ? 13.22597 -29.69784 -6.71880  1.000 46.35376 ? 840  HOH A O   1 
HETATM 7767 O  O   . HOH BA 7 .   ? 37.59718 18.86432  -22.09741 1.000 26.98543 ? 841  HOH A O   1 
HETATM 7768 O  O   . HOH BA 7 .   ? 43.48392 4.74299   -6.90233  1.000 20.25212 ? 842  HOH A O   1 
HETATM 7769 O  O   . HOH BA 7 .   ? 14.21978 8.93781   -32.54486 1.000 29.25618 ? 843  HOH A O   1 
HETATM 7770 O  O   . HOH BA 7 .   ? 44.25381 -18.26517 -11.02776 1.000 27.29841 ? 844  HOH A O   1 
HETATM 7771 O  O   . HOH BA 7 .   ? 31.64486 -21.94167 -28.81108 1.000 39.21990 ? 845  HOH A O   1 
HETATM 7772 O  O   . HOH BA 7 .   ? 25.92906 17.83641  -22.90358 1.000 18.35399 ? 846  HOH A O   1 
HETATM 7773 O  O   . HOH BA 7 .   ? 29.71186 -17.61129 10.80904  1.000 37.80463 ? 847  HOH A O   1 
HETATM 7774 O  O   . HOH BA 7 .   ? 30.62910 -0.65139  -19.95310 1.000 16.62667 ? 848  HOH A O   1 
HETATM 7775 O  O   . HOH BA 7 .   ? 23.12151 -13.21702 -12.68503 1.000 16.58945 ? 849  HOH A O   1 
HETATM 7776 O  O   . HOH BA 7 .   ? 13.00215 -9.20322  -15.94815 1.000 23.28170 ? 850  HOH A O   1 
HETATM 7777 O  O   . HOH BA 7 .   ? 44.87253 -24.78977 -8.19046  1.000 34.33024 ? 851  HOH A O   1 
HETATM 7778 O  O   . HOH BA 7 .   ? 29.34106 -22.51658 -25.83084 1.000 34.19388 ? 852  HOH A O   1 
HETATM 7779 O  O   . HOH BA 7 .   ? 22.20949 -23.91540 -25.02005 1.000 35.62889 ? 853  HOH A O   1 
HETATM 7780 O  O   . HOH BA 7 .   ? 29.59536 2.35921   -6.56532  1.000 15.04312 ? 854  HOH A O   1 
HETATM 7781 O  O   . HOH BA 7 .   ? 25.85791 -22.44736 -24.42000 1.000 33.85795 ? 855  HOH A O   1 
HETATM 7782 O  O   . HOH BA 7 .   ? 36.99768 -10.03534 -26.64404 1.000 36.75849 ? 856  HOH A O   1 
HETATM 7783 O  O   . HOH BA 7 .   ? 17.95991 -10.22240 12.34776  1.000 29.37653 ? 857  HOH A O   1 
HETATM 7784 O  O   . HOH BA 7 .   ? 24.43290 -32.03556 -14.14968 1.000 39.17681 ? 858  HOH A O   1 
HETATM 7785 O  O   . HOH BA 7 .   ? 53.59850 -10.68404 -10.07396 1.000 44.33175 ? 859  HOH A O   1 
HETATM 7786 O  O   . HOH BA 7 .   ? 22.40712 -7.83863  -21.19304 1.000 20.00935 ? 860  HOH A O   1 
HETATM 7787 O  O   . HOH BA 7 .   ? 15.13301 9.72461   1.08716   1.000 41.27573 ? 861  HOH A O   1 
HETATM 7788 O  O   . HOH BA 7 .   ? 14.38398 -15.67728 -26.59039 1.000 25.54562 ? 862  HOH A O   1 
HETATM 7789 O  O   . HOH BA 7 .   ? 28.49794 -32.22517 -14.35543 1.000 32.72898 ? 863  HOH A O   1 
HETATM 7790 O  O   . HOH BA 7 .   ? 5.00681  -9.44730  -3.64469  1.000 33.96262 ? 864  HOH A O   1 
HETATM 7791 O  O   . HOH BA 7 .   ? 45.62598 0.48226   -15.04109 1.000 24.08882 ? 865  HOH A O   1 
HETATM 7792 O  O   . HOH BA 7 .   ? 27.385   -37.985   -7.353    1.000 35.67354 ? 866  HOH A O   1 
HETATM 7793 O  O   . HOH BA 7 .   ? 22.32192 -17.45744 -20.82699 1.000 18.82577 ? 867  HOH A O   1 
HETATM 7794 O  O   . HOH BA 7 .   ? 29.11483 -32.36572 -10.97974 1.000 35.39477 ? 868  HOH A O   1 
HETATM 7795 O  O   . HOH BA 7 .   ? 16.64976 -25.44251 -20.95931 1.000 31.17983 ? 869  HOH A O   1 
HETATM 7796 O  O   . HOH BA 7 .   ? 38.25061 -5.54303  -27.74783 1.000 30.46488 ? 870  HOH A O   1 
HETATM 7797 O  O   . HOH BA 7 .   ? 16.77546 -13.33989 -18.54345 1.000 19.89846 ? 871  HOH A O   1 
HETATM 7798 O  O   . HOH BA 7 .   ? 15.30380 5.50865   -37.47680 1.000 31.29411 ? 872  HOH A O   1 
HETATM 7799 O  O   . HOH BA 7 .   ? 23.143   9.082     -39.102   1.000 30.36917 ? 873  HOH A O   1 
HETATM 7800 O  O   . HOH BA 7 .   ? 43.44564 -13.62170 -19.91483 1.000 38.47292 ? 874  HOH A O   1 
HETATM 7801 O  O   . HOH BA 7 .   ? 21.29722 -10.17796 -20.49428 1.000 32.52795 ? 875  HOH A O   1 
HETATM 7802 O  O   . HOH BA 7 .   ? 11.98688 -20.85404 -19.98182 1.000 41.71410 ? 876  HOH A O   1 
HETATM 7803 O  O   . HOH BA 7 .   ? 29.98213 10.47255  -2.71996  1.000 22.78172 ? 877  HOH A O   1 
HETATM 7804 O  O   . HOH BA 7 .   ? 7.68186  -5.10526  -7.30198  1.000 31.53201 ? 878  HOH A O   1 
HETATM 7805 O  O   . HOH BA 7 .   ? 37.68972 4.03519   -13.69576 1.000 21.86688 ? 879  HOH A O   1 
HETATM 7806 O  O   . HOH BA 7 .   ? 35.28795 -8.00373  -32.33023 1.000 42.46020 ? 880  HOH A O   1 
HETATM 7807 O  O   . HOH BA 7 .   ? 43.00911 0.34413   -27.25196 1.000 35.93867 ? 881  HOH A O   1 
HETATM 7808 O  O   . HOH BA 7 .   ? 22.20820 11.49499  -31.46088 1.000 38.33644 ? 882  HOH A O   1 
HETATM 7809 O  O   . HOH BA 7 .   ? 39.73241 26.92640  -26.32944 1.000 44.34859 ? 883  HOH A O   1 
HETATM 7810 O  O   . HOH BA 7 .   ? 30.45538 -38.66488 1.41615   1.000 38.51454 ? 884  HOH A O   1 
HETATM 7811 O  O   . HOH BA 7 .   ? 16.57540 -26.78876 0.58714   1.000 36.66466 ? 885  HOH A O   1 
HETATM 7812 O  O   . HOH BA 7 .   ? 41.68441 -3.02064  -6.19802  1.000 18.10754 ? 886  HOH A O   1 
HETATM 7813 O  O   . HOH BA 7 .   ? 43.22789 11.53542  -29.37892 1.000 38.73416 ? 887  HOH A O   1 
HETATM 7814 O  O   . HOH BA 7 .   ? 34.02461 -20.72952 -26.53381 1.000 37.05294 ? 888  HOH A O   1 
HETATM 7815 O  O   . HOH BA 7 .   ? 22.11942 1.64872   -21.81700 1.000 17.77301 ? 889  HOH A O   1 
HETATM 7816 O  O   . HOH BA 7 .   ? 48.24467 6.37162   -16.69037 1.000 33.19325 ? 890  HOH A O   1 
HETATM 7817 O  O   . HOH BA 7 .   ? 50.62296 -15.89899 -0.07408  1.000 45.91802 ? 891  HOH A O   1 
HETATM 7818 O  O   . HOH BA 7 .   ? 30.52142 19.68578  -17.74967 1.000 35.18467 ? 892  HOH A O   1 
HETATM 7819 O  O   . HOH BA 7 .   ? 41.73531 -6.87315  4.50508   1.000 20.03202 ? 893  HOH A O   1 
HETATM 7820 O  O   . HOH BA 7 .   ? 19.06665 8.51507   10.77634  1.000 39.63235 ? 894  HOH A O   1 
HETATM 7821 O  O   . HOH BA 7 .   ? 42.25718 -15.17181 3.00631   1.000 21.38603 ? 895  HOH A O   1 
HETATM 7822 O  O   . HOH BA 7 .   ? 30.10221 15.04355  -29.24613 1.000 21.27681 ? 896  HOH A O   1 
HETATM 7823 O  O   . HOH BA 7 .   ? 21.63854 -14.89976 -28.55750 1.000 27.88882 ? 897  HOH A O   1 
HETATM 7824 O  O   . HOH BA 7 .   ? 28.05001 -32.97116 3.46174   1.000 31.62882 ? 898  HOH A O   1 
HETATM 7825 O  O   . HOH BA 7 .   ? 41.14103 23.11436  -27.32089 1.000 38.23866 ? 899  HOH A O   1 
HETATM 7826 O  O   . HOH BA 7 .   ? 38.48966 -16.76282 -31.67907 1.000 46.83080 ? 900  HOH A O   1 
HETATM 7827 O  O   . HOH BA 7 .   ? 12.91070 7.25545   2.50368   1.000 32.86631 ? 901  HOH A O   1 
HETATM 7828 O  O   . HOH BA 7 .   ? 29.38632 -0.98053  9.71573   1.000 25.96569 ? 902  HOH A O   1 
HETATM 7829 O  O   . HOH BA 7 .   ? 27.19948 -3.17272  -28.73425 1.000 26.13722 ? 903  HOH A O   1 
HETATM 7830 O  O   . HOH BA 7 .   ? -4.20276 -15.87034 -4.38429  1.000 41.95322 ? 904  HOH A O   1 
HETATM 7831 O  O   . HOH BA 7 .   ? 36.12986 26.18321  -22.63760 1.000 37.93430 ? 905  HOH A O   1 
HETATM 7832 O  O   . HOH BA 7 .   ? 42.12333 7.21952   -3.78858  1.000 32.10890 ? 906  HOH A O   1 
HETATM 7833 O  O   . HOH BA 7 .   ? 7.23171  -22.39214 -6.91798  1.000 33.16759 ? 907  HOH A O   1 
HETATM 7834 O  O   . HOH BA 7 .   ? 37.05665 -19.23119 2.45101   1.000 19.62124 ? 908  HOH A O   1 
HETATM 7835 O  O   . HOH BA 7 .   ? 45.84282 -9.81743  -20.74508 1.000 43.46063 ? 909  HOH A O   1 
HETATM 7836 O  O   . HOH BA 7 .   ? 49.55331 1.75969   -14.61314 1.000 28.02434 ? 910  HOH A O   1 
HETATM 7837 O  O   . HOH BA 7 .   ? 20.21449 -25.81744 3.58169   1.000 27.00187 ? 911  HOH A O   1 
HETATM 7838 O  O   . HOH BA 7 .   ? 43.00678 -3.46951  -21.33820 1.000 36.85258 ? 912  HOH A O   1 
HETATM 7839 O  O   . HOH BA 7 .   ? 10.72371 -4.07811  12.66985  1.000 35.33479 ? 913  HOH A O   1 
HETATM 7840 O  O   . HOH BA 7 .   ? 25.46677 -27.27191 -19.12171 1.000 28.45053 ? 914  HOH A O   1 
HETATM 7841 O  O   . HOH BA 7 .   ? 36.19302 -1.34110  -36.84139 1.000 41.45364 ? 915  HOH A O   1 
HETATM 7842 O  O   . HOH BA 7 .   ? 18.23549 -0.44923  -4.24735  1.000 18.69197 ? 916  HOH A O   1 
HETATM 7843 O  O   . HOH BA 7 .   ? 32.11893 13.85087  -5.98947  1.000 22.57279 ? 917  HOH A O   1 
HETATM 7844 O  O   . HOH BA 7 .   ? 42.75432 -15.92063 6.38335   1.000 27.99200 ? 918  HOH A O   1 
HETATM 7845 O  O   . HOH BA 7 .   ? 24.19307 -28.94665 -16.52084 1.000 30.76653 ? 919  HOH A O   1 
HETATM 7846 O  O   . HOH BA 7 .   ? 7.83594  -15.66842 -24.15209 1.000 35.41988 ? 920  HOH A O   1 
HETATM 7847 O  O   . HOH BA 7 .   ? 24.53056 0.39480   -22.22390 1.000 17.23964 ? 921  HOH A O   1 
HETATM 7848 O  O   . HOH BA 7 .   ? 11.86218 -3.77943  -17.89364 1.000 38.62527 ? 922  HOH A O   1 
HETATM 7849 O  O   . HOH BA 7 .   ? 46.57715 3.40754   -9.53629  1.000 25.32298 ? 923  HOH A O   1 
HETATM 7850 O  O   . HOH BA 7 .   ? 15.41646 9.41512   -34.81816 1.000 43.51377 ? 924  HOH A O   1 
HETATM 7851 O  O   . HOH BA 7 .   ? 12.19421 -13.82660 -13.44785 1.000 30.59860 ? 925  HOH A O   1 
HETATM 7852 O  O   . HOH BA 7 .   ? 24.31459 10.69970  -18.83286 1.000 17.95080 ? 926  HOH A O   1 
HETATM 7853 O  O   . HOH BA 7 .   ? 43.70019 -18.61510 -17.00976 1.000 39.70380 ? 927  HOH A O   1 
HETATM 7854 O  O   . HOH BA 7 .   ? 41.49697 -19.46643 -26.74290 1.000 45.69452 ? 928  HOH A O   1 
HETATM 7855 O  O   . HOH BA 7 .   ? 19.40109 -1.46768  -20.82165 1.000 19.47524 ? 929  HOH A O   1 
HETATM 7856 O  O   . HOH BA 7 .   ? 32.79388 -0.06657  -33.97360 1.000 32.71918 ? 930  HOH A O   1 
HETATM 7857 O  O   . HOH BA 7 .   ? 36.20144 -3.05621  -1.56776  1.000 18.14779 ? 931  HOH A O   1 
HETATM 7858 O  O   . HOH BA 7 .   ? 34.81101 -12.85369 -15.52768 1.000 18.05497 ? 932  HOH A O   1 
HETATM 7859 O  O   . HOH BA 7 .   ? 10.81823 -16.81365 -11.52165 1.000 28.85716 ? 933  HOH A O   1 
HETATM 7860 O  O   . HOH BA 7 .   ? 29.19541 -0.26250  -5.46713  1.000 15.02040 ? 934  HOH A O   1 
HETATM 7861 O  O   . HOH BA 7 .   ? 26.23388 6.60668   10.58945  1.000 40.38730 ? 935  HOH A O   1 
HETATM 7862 O  O   . HOH BA 7 .   ? 34.85434 3.27586   -33.26619 1.000 35.46996 ? 936  HOH A O   1 
HETATM 7863 O  O   . HOH BA 7 .   ? 22.36992 -5.60050  -26.15471 1.000 20.43596 ? 937  HOH A O   1 
HETATM 7864 O  O   . HOH BA 7 .   ? 15.87847 -12.13127 10.28481  1.000 28.45391 ? 938  HOH A O   1 
HETATM 7865 O  O   . HOH BA 7 .   ? 20.03845 6.32345   -15.80548 1.000 33.25977 ? 939  HOH A O   1 
HETATM 7866 O  O   . HOH BA 7 .   ? 31.98863 14.77134  -18.98083 1.000 18.65861 ? 940  HOH A O   1 
HETATM 7867 O  O   . HOH BA 7 .   ? 14.31510 -1.90081  17.48945  1.000 32.63669 ? 941  HOH A O   1 
HETATM 7868 O  O   . HOH BA 7 .   ? 28.25193 -16.61662 12.61949  1.000 44.58728 ? 942  HOH A O   1 
HETATM 7869 O  O   . HOH BA 7 .   ? 38.37810 -15.96242 8.16595   1.000 37.23992 ? 943  HOH A O   1 
HETATM 7870 O  O   . HOH BA 7 .   ? 32.95329 18.28048  -18.22408 1.000 25.49647 ? 944  HOH A O   1 
HETATM 7871 O  O   . HOH BA 7 .   ? 17.40460 6.74043   -1.29688  1.000 30.76377 ? 945  HOH A O   1 
HETATM 7872 O  O   . HOH BA 7 .   ? 38.87097 11.07611  -32.91381 1.000 47.69538 ? 946  HOH A O   1 
HETATM 7873 O  O   . HOH BA 7 .   ? 32.30854 -14.35131 8.39574   1.000 24.04340 ? 947  HOH A O   1 
HETATM 7874 O  O   . HOH BA 7 .   ? 25.77134 12.81808  -13.68163 1.000 25.34243 ? 948  HOH A O   1 
HETATM 7875 O  O   . HOH BA 7 .   ? 47.26102 6.49543   -27.20110 1.000 35.31176 ? 949  HOH A O   1 
HETATM 7876 O  O   A HOH BA 7 .   ? 40.52735 -5.87240  -22.20496 0.473 28.54165 ? 950  HOH A O   1 
HETATM 7877 O  O   B HOH BA 7 .   ? 42.33218 -6.23121  -22.94093 0.527 36.07322 ? 950  HOH A O   1 
HETATM 7878 O  O   . HOH BA 7 .   ? 29.57133 -13.57438 -28.61849 1.000 34.79178 ? 951  HOH A O   1 
HETATM 7879 O  O   . HOH BA 7 .   ? 44.96649 -3.54473  6.16993   1.000 39.94405 ? 952  HOH A O   1 
HETATM 7880 O  O   . HOH BA 7 .   ? 9.57612  -20.74042 -12.79523 1.000 35.40420 ? 953  HOH A O   1 
HETATM 7881 O  O   . HOH BA 7 .   ? 11.88882 -0.10560  7.30620   1.000 39.83238 ? 954  HOH A O   1 
HETATM 7882 O  O   . HOH BA 7 .   ? 43.80708 -26.40966 6.66550   1.000 50.50061 ? 955  HOH A O   1 
HETATM 7883 O  O   . HOH BA 7 .   ? 15.88109 -3.31820  -17.07041 1.000 21.38932 ? 956  HOH A O   1 
HETATM 7884 O  O   . HOH BA 7 .   ? 40.96847 5.91873   -6.60408  1.000 18.74162 ? 957  HOH A O   1 
HETATM 7885 O  O   . HOH BA 7 .   ? 16.72847 12.44804  -30.90515 1.000 40.74650 ? 958  HOH A O   1 
HETATM 7886 O  O   . HOH BA 7 .   ? 25.99533 8.23577   -3.10036  1.000 21.51268 ? 959  HOH A O   1 
HETATM 7887 O  O   . HOH BA 7 .   ? 12.09806 -17.40122 -13.76021 1.000 24.82017 ? 960  HOH A O   1 
HETATM 7888 O  O   . HOH BA 7 .   ? 36.76966 20.86633  -12.41254 1.000 30.95012 ? 961  HOH A O   1 
HETATM 7889 O  O   . HOH BA 7 .   ? 48.17235 -12.51678 0.11270   1.000 29.67337 ? 962  HOH A O   1 
HETATM 7890 O  O   . HOH BA 7 .   ? 37.30036 23.21739  -32.34557 1.000 32.52475 ? 963  HOH A O   1 
HETATM 7891 O  O   . HOH BA 7 .   ? 37.48915 13.89260  -4.86741  1.000 25.78607 ? 964  HOH A O   1 
HETATM 7892 O  O   . HOH BA 7 .   ? 26.97926 12.29604  -7.18783  1.000 23.06457 ? 965  HOH A O   1 
HETATM 7893 O  O   . HOH BA 7 .   ? 20.27386 -16.20866 9.42380   1.000 36.22084 ? 966  HOH A O   1 
HETATM 7894 O  O   . HOH BA 7 .   ? 47.90572 -15.87917 -11.63770 1.000 31.65367 ? 967  HOH A O   1 
HETATM 7895 O  O   . HOH BA 7 .   ? 11.92767 -22.48555 -27.35508 1.000 35.64127 ? 968  HOH A O   1 
HETATM 7896 O  O   . HOH BA 7 .   ? 38.17301 -28.54793 -3.01082  1.000 38.82860 ? 969  HOH A O   1 
HETATM 7897 O  O   . HOH BA 7 .   ? 22.10656 -17.23427 -10.52753 1.000 27.93762 ? 970  HOH A O   1 
HETATM 7898 O  O   . HOH BA 7 .   ? 25.21267 -25.53626 8.56683   1.000 43.93189 ? 971  HOH A O   1 
HETATM 7899 O  O   . HOH BA 7 .   ? 34.55801 -33.30530 1.51651   1.000 42.00543 ? 972  HOH A O   1 
HETATM 7900 O  O   . HOH BA 7 .   ? 41.36766 -5.14325  6.40214   1.000 30.16882 ? 973  HOH A O   1 
HETATM 7901 O  O   . HOH BA 7 .   ? 14.81530 -7.68223  -7.18004  1.000 18.82247 ? 974  HOH A O   1 
HETATM 7902 O  O   . HOH BA 7 .   ? 46.60742 2.17192   -7.24237  1.000 32.55560 ? 975  HOH A O   1 
HETATM 7903 O  O   . HOH BA 7 .   ? 6.69431  -14.94181 3.12902   1.000 24.12906 ? 976  HOH A O   1 
HETATM 7904 O  O   . HOH BA 7 .   ? 47.37751 -20.30877 -6.92227  1.000 45.93790 ? 977  HOH A O   1 
HETATM 7905 O  O   . HOH BA 7 .   ? 26.91393 5.41458   -35.81459 1.000 24.69226 ? 978  HOH A O   1 
HETATM 7906 O  O   A HOH BA 7 .   ? 9.86768  0.08433   1.15230   0.462 28.21188 ? 979  HOH A O   1 
HETATM 7907 O  O   B HOH BA 7 .   ? 11.11569 1.40797   2.37773   0.538 26.43937 ? 979  HOH A O   1 
HETATM 7908 O  O   . HOH BA 7 .   ? 38.03986 2.46194   -2.07706  1.000 34.69009 ? 980  HOH A O   1 
HETATM 7909 O  O   . HOH BA 7 .   ? 14.59856 -9.43858  -18.08737 1.000 21.72003 ? 981  HOH A O   1 
HETATM 7910 O  O   . HOH BA 7 .   ? 17.82990 6.71700   1.17388   1.000 37.05337 ? 982  HOH A O   1 
HETATM 7911 O  O   . HOH BA 7 .   ? 18.97930 -19.10170 5.45384   1.000 28.03701 ? 983  HOH A O   1 
HETATM 7912 O  O   . HOH BA 7 .   ? 39.40130 -26.71892 3.19693   1.000 27.25525 ? 984  HOH A O   1 
HETATM 7913 O  O   . HOH BA 7 .   ? 14.08025 -11.15825 -31.37984 1.000 43.23770 ? 985  HOH A O   1 
HETATM 7914 O  O   . HOH BA 7 .   ? 46.05464 19.20489  -27.59443 1.000 49.58736 ? 986  HOH A O   1 
HETATM 7915 O  O   . HOH BA 7 .   ? 34.65521 20.24642  -16.82347 1.000 40.03429 ? 987  HOH A O   1 
HETATM 7916 O  O   . HOH BA 7 .   ? 22.04875 -7.17558  -34.20830 1.000 40.03233 ? 988  HOH A O   1 
HETATM 7917 O  O   . HOH BA 7 .   ? 48.91229 5.52212   -6.54074  1.000 32.31222 ? 989  HOH A O   1 
HETATM 7918 O  O   . HOH BA 7 .   ? 37.11648 -28.65978 0.13888   1.000 41.40248 ? 990  HOH A O   1 
HETATM 7919 O  O   . HOH BA 7 .   ? 32.35291 -21.59382 14.55375  1.000 48.72738 ? 991  HOH A O   1 
HETATM 7920 O  O   . HOH BA 7 .   ? 11.35167 -10.39092 -26.11547 1.000 28.30025 ? 992  HOH A O   1 
HETATM 7921 O  O   . HOH BA 7 .   ? 19.84368 -8.57304  -19.35200 1.000 20.47080 ? 993  HOH A O   1 
HETATM 7922 O  O   . HOH BA 7 .   ? 4.57550  -17.11749 -7.45856  1.000 29.84865 ? 994  HOH A O   1 
HETATM 7923 O  O   . HOH BA 7 .   ? 27.85178 9.91718   -29.77065 1.000 29.59149 ? 995  HOH A O   1 
HETATM 7924 O  O   . HOH BA 7 .   ? 16.58424 -31.43407 -9.77971  1.000 43.02309 ? 996  HOH A O   1 
HETATM 7925 O  O   . HOH BA 7 .   ? 36.29706 17.83184  -24.43612 1.000 21.00657 ? 997  HOH A O   1 
HETATM 7926 O  O   . HOH BA 7 .   ? 21.76830 -30.14644 -14.66763 1.000 41.37342 ? 998  HOH A O   1 
HETATM 7927 O  O   . HOH BA 7 .   ? 31.52158 6.69412   -35.75073 1.000 31.14880 ? 999  HOH A O   1 
HETATM 7928 O  O   . HOH BA 7 .   ? 48.08311 -4.85595  2.19191   1.000 32.29145 ? 1000 HOH A O   1 
HETATM 7929 O  O   . HOH BA 7 .   ? 25.49759 -36.67630 -9.83019  1.000 44.52232 ? 1001 HOH A O   1 
HETATM 7930 O  O   . HOH BA 7 .   ? 53.54077 -4.04312  -9.72159  1.000 27.59917 ? 1002 HOH A O   1 
HETATM 7931 O  O   . HOH BA 7 .   ? 39.74122 17.10937  -30.83831 1.000 30.38535 ? 1003 HOH A O   1 
HETATM 7932 O  O   . HOH BA 7 .   ? 45.90356 -13.68936 -17.95921 1.000 34.47264 ? 1004 HOH A O   1 
HETATM 7933 O  O   . HOH BA 7 .   ? 14.47608 -7.78791  -24.43164 1.000 24.40587 ? 1005 HOH A O   1 
HETATM 7934 O  O   . HOH BA 7 .   ? 4.36168  -22.86855 -3.62365  1.000 46.71594 ? 1006 HOH A O   1 
HETATM 7935 O  O   . HOH BA 7 .   ? 41.08205 10.83971  -3.60854  1.000 25.69831 ? 1007 HOH A O   1 
HETATM 7936 O  O   . HOH BA 7 .   ? 39.65570 -28.67009 -1.02507  1.000 42.17972 ? 1008 HOH A O   1 
HETATM 7937 O  O   . HOH BA 7 .   ? 11.92589 -13.02582 -17.68194 1.000 27.38544 ? 1009 HOH A O   1 
HETATM 7938 O  O   . HOH BA 7 .   ? 18.52991 -11.28675 -30.52283 1.000 36.62375 ? 1010 HOH A O   1 
HETATM 7939 O  O   . HOH BA 7 .   ? 25.92679 -4.89002  -27.20845 1.000 26.39337 ? 1011 HOH A O   1 
HETATM 7940 O  O   . HOH BA 7 .   ? 11.08176 -15.84883 5.99108   1.000 29.59984 ? 1012 HOH A O   1 
HETATM 7941 O  O   . HOH BA 7 .   ? 40.88511 -20.03563 8.78049   1.000 48.62660 ? 1013 HOH A O   1 
HETATM 7942 O  O   . HOH BA 7 .   ? 40.582   2.701     -38.381   1.000 55.54420 ? 1014 HOH A O   1 
HETATM 7943 O  O   . HOH BA 7 .   ? 13.06193 -24.77366 -27.34611 1.000 47.89721 ? 1015 HOH A O   1 
HETATM 7944 O  O   . HOH BA 7 .   ? 51.139   14.459    -6.989    1.000 39.02080 ? 1016 HOH A O   1 
HETATM 7945 O  O   . HOH BA 7 .   ? 0.53164  -13.39113 -17.90909 1.000 47.47158 ? 1017 HOH A O   1 
HETATM 7946 O  O   . HOH BA 7 .   ? 38.53783 -13.64653 12.55329  1.000 47.85259 ? 1018 HOH A O   1 
HETATM 7947 O  O   . HOH BA 7 .   ? 43.54574 -23.09231 -22.05310 1.000 41.68323 ? 1019 HOH A O   1 
HETATM 7948 O  O   . HOH BA 7 .   ? 38.42946 28.91483  -27.67569 1.000 32.81481 ? 1020 HOH A O   1 
HETATM 7949 O  O   A HOH BA 7 .   ? 44.78842 -1.73629  -22.51293 0.340 21.95552 ? 1021 HOH A O   1 
HETATM 7950 O  O   B HOH BA 7 .   ? 45.23426 -0.79378  -22.89424 0.660 19.68919 ? 1021 HOH A O   1 
HETATM 7951 O  O   . HOH BA 7 .   ? 17.26158 0.25871   -9.44248  1.000 22.19640 ? 1022 HOH A O   1 
HETATM 7952 O  O   . HOH BA 7 .   ? 10.21201 6.11581   9.07054   1.000 46.95969 ? 1023 HOH A O   1 
HETATM 7953 O  O   . HOH BA 7 .   ? 11.25938 8.22035   5.94529   1.000 37.88829 ? 1024 HOH A O   1 
HETATM 7954 O  O   . HOH BA 7 .   ? 3.15117  -12.49173 -18.61820 1.000 45.95181 ? 1025 HOH A O   1 
HETATM 7955 O  O   . HOH BA 7 .   ? 9.74900  -3.96782  4.09309   1.000 30.47325 ? 1026 HOH A O   1 
HETATM 7956 O  O   . HOH BA 7 .   ? 8.55131  -5.56444  -12.48577 1.000 43.91304 ? 1027 HOH A O   1 
HETATM 7957 O  O   . HOH BA 7 .   ? 47.94789 -13.84733 7.39859   1.000 34.34197 ? 1028 HOH A O   1 
HETATM 7958 O  O   . HOH BA 7 .   ? 50.916   10.272    -12.254   1.000 43.81849 ? 1029 HOH A O   1 
HETATM 7959 O  O   . HOH BA 7 .   ? 29.58200 -11.74188 -30.29062 1.000 41.98737 ? 1030 HOH A O   1 
HETATM 7960 O  O   . HOH BA 7 .   ? 9.85021  0.49946   8.63241   1.000 48.02242 ? 1031 HOH A O   1 
HETATM 7961 O  O   . HOH BA 7 .   ? 50.27126 20.09862  -25.71209 1.000 51.11831 ? 1032 HOH A O   1 
HETATM 7962 O  O   . HOH BA 7 .   ? 10.81434 -0.10760  -3.63614  1.000 26.33388 ? 1033 HOH A O   1 
HETATM 7963 O  O   . HOH BA 7 .   ? 21.62537 -3.32625  15.96991  1.000 25.25165 ? 1034 HOH A O   1 
HETATM 7964 O  O   . HOH BA 7 .   ? 6.83295  -14.15700 -19.82304 1.000 43.76027 ? 1035 HOH A O   1 
HETATM 7965 O  O   . HOH BA 7 .   ? 7.16010  -2.96364  -1.97146  1.000 31.71197 ? 1036 HOH A O   1 
HETATM 7966 O  O   . HOH BA 7 .   ? 27.09617 13.98015  -34.52470 1.000 45.95229 ? 1037 HOH A O   1 
HETATM 7967 O  O   A HOH BA 7 .   ? 8.59267  -9.63015  8.21818   0.589 28.13006 ? 1038 HOH A O   1 
HETATM 7968 O  O   B HOH BA 7 .   ? 9.44611  -11.09921 8.48210   0.411 30.17919 ? 1038 HOH A O   1 
HETATM 7969 O  O   . HOH BA 7 .   ? 33.60146 -12.89711 -31.25155 1.000 49.84498 ? 1039 HOH A O   1 
HETATM 7970 O  O   . HOH BA 7 .   ? 18.00960 0.89143   -40.86316 1.000 35.62556 ? 1040 HOH A O   1 
HETATM 7971 O  O   . HOH BA 7 .   ? 22.40100 -17.67551 -28.94732 1.000 26.51592 ? 1041 HOH A O   1 
HETATM 7972 O  O   . HOH BA 7 .   ? 11.93716 2.27387   -3.34541  1.000 37.97441 ? 1042 HOH A O   1 
HETATM 7973 O  O   . HOH BA 7 .   ? 41.68017 -13.67782 -25.57439 1.000 39.91204 ? 1043 HOH A O   1 
HETATM 7974 O  O   . HOH BA 7 .   ? 37.67163 -5.60235  -25.20109 1.000 29.63378 ? 1044 HOH A O   1 
HETATM 7975 O  O   . HOH BA 7 .   ? 3.88105  -7.00632  -17.23498 1.000 48.25438 ? 1045 HOH A O   1 
HETATM 7976 O  O   . HOH BA 7 .   ? 10.08237 -1.43106  5.69663   1.000 47.91095 ? 1046 HOH A O   1 
HETATM 7977 O  O   . HOH BA 7 .   ? 14.25307 -26.32854 -2.01109  1.000 41.53507 ? 1047 HOH A O   1 
HETATM 7978 O  O   . HOH BA 7 .   ? 24.16508 6.90539   5.28508   1.000 42.24185 ? 1048 HOH A O   1 
HETATM 7979 O  O   . HOH BA 7 .   ? 6.85736  -6.23698  1.40652   1.000 40.96799 ? 1049 HOH A O   1 
HETATM 7980 O  O   . HOH BA 7 .   ? 37.09774 -26.79527 -27.55432 1.000 50.28220 ? 1050 HOH A O   1 
HETATM 7981 O  O   . HOH BA 7 .   ? -5.53987 -9.66625  -12.66074 1.000 43.71149 ? 1051 HOH A O   1 
HETATM 7982 O  O   . HOH BA 7 .   ? 29.10955 -24.70036 -24.70811 1.000 47.11426 ? 1052 HOH A O   1 
HETATM 7983 O  O   . HOH BA 7 .   ? 21.81067 -20.36711 -31.46904 1.000 52.24172 ? 1053 HOH A O   1 
HETATM 7984 O  O   . HOH BA 7 .   ? 30.05601 4.88184   -35.07257 1.000 25.35106 ? 1054 HOH A O   1 
HETATM 7985 O  O   A HOH BA 7 .   ? 27.39167 13.87903  -30.03770 0.552 24.55185 ? 1055 HOH A O   1 
HETATM 7986 O  O   B HOH BA 7 .   ? 28.47766 12.79449  -29.02295 0.448 20.00465 ? 1055 HOH A O   1 
HETATM 7987 O  O   . HOH BA 7 .   ? 28.80062 13.21705  -35.78650 1.000 43.43141 ? 1056 HOH A O   1 
HETATM 7988 O  O   . HOH BA 7 .   ? 39.76750 -28.91440 -18.22636 1.000 38.44145 ? 1057 HOH A O   1 
HETATM 7989 O  O   . HOH BA 7 .   ? 48.31834 7.98832   -21.20799 1.000 40.56836 ? 1058 HOH A O   1 
HETATM 7990 O  O   . HOH BA 7 .   ? 25.27159 -13.10034 11.51712  1.000 36.95165 ? 1059 HOH A O   1 
HETATM 7991 O  O   . HOH BA 7 .   ? 29.123   1.327     13.181    1.000 43.40416 ? 1060 HOH A O   1 
HETATM 7992 O  O   . HOH BA 7 .   ? 30.970   -24.233   15.871    1.000 40.41351 ? 1061 HOH A O   1 
HETATM 7993 O  O   . HOH BA 7 .   ? 35.14614 5.90317   -34.45812 1.000 46.76698 ? 1062 HOH A O   1 
HETATM 7994 O  O   . HOH BA 7 .   ? 17.06235 -21.55273 -31.83401 1.000 46.30186 ? 1063 HOH A O   1 
HETATM 7995 O  O   A HOH BA 7 .   ? 15.68773 -27.28564 -3.64491  0.373 27.83901 ? 1064 HOH A O   1 
HETATM 7996 O  O   B HOH BA 7 .   ? 16.71027 -27.47630 -2.68346  0.627 27.88188 ? 1064 HOH A O   1 
HETATM 7997 O  O   . HOH BA 7 .   ? 44.78503 22.97165  -22.93905 1.000 47.96858 ? 1065 HOH A O   1 
HETATM 7998 O  O   . HOH BA 7 .   ? 26.78863 -10.97538 -30.88548 1.000 35.20457 ? 1066 HOH A O   1 
HETATM 7999 O  O   . HOH BA 7 .   ? 49.73822 6.43606   -13.35747 1.000 17.67096 ? 1067 HOH A O   1 
HETATM 8000 O  O   . HOH BA 7 .   ? 22.82232 7.26618   2.99780   1.000 35.88108 ? 1068 HOH A O   1 
HETATM 8001 O  O   . HOH BA 7 .   ? 11.28634 -23.86119 0.95727   1.000 40.23963 ? 1069 HOH A O   1 
HETATM 8002 O  O   . HOH BA 7 .   ? 27.45666 10.18271  2.56169   1.000 45.13688 ? 1070 HOH A O   1 
HETATM 8003 O  O   . HOH BA 7 .   ? -5.491   -20.755   -3.515    1.000 44.36490 ? 1071 HOH A O   1 
HETATM 8004 O  O   . HOH BA 7 .   ? 22.29769 6.42494   11.07739  1.000 39.86197 ? 1072 HOH A O   1 
HETATM 8005 O  O   . HOH BA 7 .   ? 51.30210 8.58516   -13.71025 1.000 39.61925 ? 1073 HOH A O   1 
HETATM 8006 O  O   . HOH BA 7 .   ? 17.86958 1.61067   -12.25529 1.000 28.73589 ? 1074 HOH A O   1 
HETATM 8007 O  O   . HOH BA 7 .   ? 14.35560 -21.47795 -19.66726 1.000 26.76835 ? 1075 HOH A O   1 
HETATM 8008 O  O   . HOH BA 7 .   ? 48.04973 15.02647  -10.55309 1.000 41.27550 ? 1076 HOH A O   1 
HETATM 8009 O  O   . HOH BA 7 .   ? 27.53421 10.07208  -1.33898  1.000 36.46790 ? 1077 HOH A O   1 
HETATM 8010 O  O   . HOH BA 7 .   ? 36.70028 20.93987  -20.23248 1.000 35.12258 ? 1078 HOH A O   1 
HETATM 8011 O  O   . HOH BA 7 .   ? 33.80086 -18.41577 -28.28673 1.000 45.58262 ? 1079 HOH A O   1 
HETATM 8012 O  O   A HOH BA 7 .   ? 38.60710 -16.19047 10.49772  0.371 37.58356 ? 1080 HOH A O   1 
HETATM 8013 O  O   B HOH BA 7 .   ? 36.64501 -16.70497 10.45084  0.629 38.54048 ? 1080 HOH A O   1 
HETATM 8014 O  O   . HOH BA 7 .   ? 41.43210 2.72403   0.66048   1.000 40.99469 ? 1081 HOH A O   1 
HETATM 8015 O  O   . HOH BA 7 .   ? 39.27851 21.55034  -18.74124 1.000 42.19845 ? 1082 HOH A O   1 
HETATM 8016 O  O   . HOH BA 7 .   ? 42.36683 16.91994  -6.07973  1.000 42.01802 ? 1083 HOH A O   1 
HETATM 8017 O  O   . HOH BA 7 .   ? 10.06745 -3.25170  -7.77701  1.000 32.54720 ? 1084 HOH A O   1 
HETATM 8018 O  O   . HOH BA 7 .   ? 14.19720 -25.54364 -17.47600 1.000 30.10362 ? 1085 HOH A O   1 
HETATM 8019 O  O   . HOH BA 7 .   ? 24.589   -21.544   10.821    1.000 40.70735 ? 1086 HOH A O   1 
HETATM 8020 O  O   . HOH BA 7 .   ? 37.33521 1.37836   2.91827   1.000 46.68278 ? 1087 HOH A O   1 
HETATM 8021 O  O   A HOH BA 7 .   ? 51.45432 12.43121  -21.41192 0.494 38.38578 ? 1088 HOH A O   1 
HETATM 8022 O  O   B HOH BA 7 .   ? 50.98573 10.69679  -20.93465 0.506 34.43969 ? 1088 HOH A O   1 
HETATM 8023 O  O   . HOH BA 7 .   ? 16.46396 -10.11864 -31.54126 1.000 46.66422 ? 1089 HOH A O   1 
HETATM 8024 O  O   . HOH BA 7 .   ? 22.26330 11.95272  -11.16440 1.000 30.12598 ? 1090 HOH A O   1 
HETATM 8025 O  O   . HOH BA 7 .   ? 37.44901 -31.17602 -3.15722  1.000 43.66068 ? 1091 HOH A O   1 
HETATM 8026 O  O   A HOH BA 7 .   ? 21.83115 -14.38243 -31.12771 0.414 29.50574 ? 1092 HOH A O   1 
HETATM 8027 O  O   B HOH BA 7 .   ? 23.44821 -14.87518 -31.02669 0.586 34.48017 ? 1092 HOH A O   1 
HETATM 8028 O  O   . HOH BA 7 .   ? 16.03912 3.69404   -21.66815 1.000 25.42456 ? 1093 HOH A O   1 
HETATM 8029 O  O   . HOH BA 7 .   ? 42.31613 -15.73922 -24.55186 1.000 48.55524 ? 1094 HOH A O   1 
HETATM 8030 O  O   . HOH BA 7 .   ? 54.793   -5.167    -11.965   1.000 53.03338 ? 1095 HOH A O   1 
HETATM 8031 O  O   . HOH BA 7 .   ? 51.69636 14.04464  -14.90001 1.000 46.97582 ? 1096 HOH A O   1 
HETATM 8032 O  O   . HOH BA 7 .   ? 10.90908 0.58219   12.16430  1.000 44.67264 ? 1097 HOH A O   1 
HETATM 8033 O  O   . HOH BA 7 .   ? 32.43328 -13.62301 12.66044  1.000 49.07140 ? 1098 HOH A O   1 
HETATM 8034 O  O   . HOH BA 7 .   ? 20.27217 -16.89067 6.30409   1.000 24.71825 ? 1099 HOH A O   1 
HETATM 8035 O  O   . HOH BA 7 .   ? 14.77866 1.57292   -10.34154 1.000 28.49285 ? 1100 HOH A O   1 
HETATM 8036 O  O   . HOH BA 7 .   ? 11.49736 -15.09281 -15.76323 1.000 30.70244 ? 1101 HOH A O   1 
HETATM 8037 O  O   . HOH BA 7 .   ? 19.07266 -29.37328 -19.53701 1.000 48.02397 ? 1102 HOH A O   1 
HETATM 8038 O  O   A HOH BA 7 .   ? 25.19264 1.15556   14.79642  0.533 38.57228 ? 1103 HOH A O   1 
HETATM 8039 O  O   B HOH BA 7 .   ? 26.87416 0.61551   15.48834  0.467 33.28302 ? 1103 HOH A O   1 
HETATM 8040 O  O   . HOH BA 7 .   ? 35.18521 -31.46417 -1.23448  1.000 36.39821 ? 1104 HOH A O   1 
HETATM 8041 O  O   . HOH BA 7 .   ? 45.12428 -21.39559 7.14959   1.000 48.85264 ? 1105 HOH A O   1 
HETATM 8042 O  O   . HOH BA 7 .   ? 49.50477 -15.87532 -14.34297 1.000 51.29882 ? 1106 HOH A O   1 
HETATM 8043 O  O   . HOH BA 7 .   ? 44.76279 3.59936   -4.79948  1.000 39.31588 ? 1107 HOH A O   1 
HETATM 8044 O  O   . HOH BA 7 .   ? 19.37170 1.19427   -21.40237 1.000 17.36906 ? 1108 HOH A O   1 
HETATM 8045 O  O   . HOH BA 7 .   ? 24.62524 5.11102   12.49867  1.000 48.86138 ? 1109 HOH A O   1 
HETATM 8046 O  O   . HOH BA 7 .   ? 53.378   -2.526    0.163     1.000 33.80623 ? 1110 HOH A O   1 
HETATM 8047 O  O   A HOH BA 7 .   ? 46.35240 -20.03599 -11.02583 0.526 27.73607 ? 1111 HOH A O   1 
HETATM 8048 O  O   B HOH BA 7 .   ? 46.77928 -20.27631 -12.88433 0.474 30.05560 ? 1111 HOH A O   1 
HETATM 8049 O  O   . HOH BA 7 .   ? 39.97084 -4.53757  -23.87308 1.000 43.28373 ? 1112 HOH A O   1 
HETATM 8050 O  O   . HOH BA 7 .   ? 40.83211 -17.14735 8.02643   1.000 41.54658 ? 1113 HOH A O   1 
HETATM 8051 O  O   . HOH BA 7 .   ? 46.23078 4.31055   -29.26407 1.000 47.43567 ? 1114 HOH A O   1 
HETATM 8052 O  O   . HOH BA 7 .   ? 23.70428 14.34613  -30.58432 1.000 44.31022 ? 1115 HOH A O   1 
HETATM 8053 O  O   . HOH BA 7 .   ? 11.97956 -27.44553 -17.78907 1.000 49.76965 ? 1116 HOH A O   1 
HETATM 8054 O  O   A HOH BA 7 .   ? 19.28254 -0.36409  17.27242  0.543 33.21525 ? 1117 HOH A O   1 
HETATM 8055 O  O   B HOH BA 7 .   ? 18.03689 -1.84752  17.54023  0.457 26.69965 ? 1117 HOH A O   1 
HETATM 8056 O  O   . HOH BA 7 .   ? 39.96452 22.19231  -21.49439 1.000 41.41700 ? 1118 HOH A O   1 
HETATM 8057 O  O   . HOH BA 7 .   ? 28.50820 -32.37045 -16.99963 1.000 45.21364 ? 1119 HOH A O   1 
HETATM 8058 O  O   . HOH BA 7 .   ? 25.85468 12.84329  -9.66004  1.000 24.72101 ? 1120 HOH A O   1 
HETATM 8059 O  O   . HOH BA 7 .   ? 18.95677 5.93328   -12.01901 1.000 42.74054 ? 1121 HOH A O   1 
HETATM 8060 O  O   . HOH BA 7 .   ? 27.74516 -23.46675 -29.32346 1.000 48.97308 ? 1122 HOH A O   1 
HETATM 8061 O  O   . HOH BA 7 .   ? 39.36771 -2.89514  9.61118   1.000 44.29760 ? 1123 HOH A O   1 
HETATM 8062 O  O   . HOH BA 7 .   ? 17.42300 11.10281  7.33479   1.000 43.99184 ? 1124 HOH A O   1 
HETATM 8063 O  O   . HOH BA 7 .   ? 19.09811 -21.77060 6.19441   1.000 30.96491 ? 1125 HOH A O   1 
HETATM 8064 O  O   . HOH BA 7 .   ? 17.87833 -27.03594 -19.15078 1.000 35.17603 ? 1126 HOH A O   1 
HETATM 8065 O  O   A HOH BA 7 .   ? 40.34860 3.89225   -1.88099  0.527 28.87938 ? 1127 HOH A O   1 
HETATM 8066 O  O   B HOH BA 7 .   ? 41.42759 4.38162   -3.52817  0.473 26.11917 ? 1127 HOH A O   1 
HETATM 8067 O  O   . HOH BA 7 .   ? 31.14955 -12.04652 13.59030  1.000 47.42276 ? 1128 HOH A O   1 
HETATM 8068 O  O   . HOH BA 7 .   ? 37.87513 21.07971  -33.65976 1.000 42.51339 ? 1129 HOH A O   1 
HETATM 8069 O  O   . HOH BA 7 .   ? 13.16064 -6.54990  -15.47511 1.000 24.89960 ? 1130 HOH A O   1 
HETATM 8070 O  O   . HOH BA 7 .   ? 11.15662 2.89546   -9.94665  1.000 50.84434 ? 1131 HOH A O   1 
HETATM 8071 O  O   . HOH BA 7 .   ? 18.57754 8.11788   -12.90439 1.000 46.58891 ? 1132 HOH A O   1 
HETATM 8072 O  O   . HOH BA 7 .   ? 12.353   -1.190    16.078    1.000 43.17217 ? 1133 HOH A O   1 
HETATM 8073 O  O   . HOH BA 7 .   ? 22.940   0.193     17.227    1.000 34.17884 ? 1134 HOH A O   1 
HETATM 8074 O  O   . HOH BA 7 .   ? 11.40020 -10.98424 -29.02111 1.000 32.27800 ? 1135 HOH A O   1 
HETATM 8075 O  O   . HOH BA 7 .   ? 32.79348 -25.87763 -24.83363 1.000 50.46565 ? 1136 HOH A O   1 
HETATM 8076 O  O   . HOH BA 7 .   ? 38.92597 -3.96987  7.14931   1.000 33.94494 ? 1137 HOH A O   1 
HETATM 8077 O  O   . HOH BA 7 .   ? 34.56209 5.59431   2.95835   1.000 32.08094 ? 1138 HOH A O   1 
HETATM 8078 O  O   . HOH BA 7 .   ? 37.60265 25.47780  -33.84589 1.000 43.99442 ? 1139 HOH A O   1 
HETATM 8079 O  O   . HOH BA 7 .   ? 14.45895 8.18257   -36.75021 1.000 39.69405 ? 1140 HOH A O   1 
HETATM 8080 O  O   . HOH BA 7 .   ? 31.86548 22.83362  -19.29523 1.000 38.40877 ? 1141 HOH A O   1 
HETATM 8081 O  O   . HOH BA 7 .   ? 51.470   -1.053    0.027     1.000 42.77493 ? 1142 HOH A O   1 
HETATM 8082 O  O   . HOH BA 7 .   ? 15.78204 6.17831   -40.40235 1.000 35.39745 ? 1143 HOH A O   1 
HETATM 8083 O  O   . HOH BA 7 .   ? 45.24082 -7.87474  -23.38077 1.000 54.33530 ? 1144 HOH A O   1 
HETATM 8084 O  O   . HOH BA 7 .   ? 40.10406 19.77359  -23.20512 1.000 34.82299 ? 1145 HOH A O   1 
HETATM 8085 O  O   . HOH BA 7 .   ? 36.43228 3.97972   -0.12999  1.000 33.77171 ? 1146 HOH A O   1 
HETATM 8086 O  O   . HOH BA 7 .   ? 21.41244 11.41001  -3.14340  1.000 47.30292 ? 1147 HOH A O   1 
HETATM 8087 O  O   . HOH BA 7 .   ? 14.38092 -24.27718 -19.88313 1.000 33.03597 ? 1148 HOH A O   1 
HETATM 8088 O  O   . HOH BA 7 .   ? 19.79857 7.93773   6.81536   1.000 35.46683 ? 1149 HOH A O   1 
HETATM 8089 O  O   . HOH BA 7 .   ? 10.16326 -0.81246  -6.58021  1.000 37.46408 ? 1150 HOH A O   1 
HETATM 8090 O  O   . HOH BA 7 .   ? 2.55053  -7.43106  -9.61864  1.000 47.56572 ? 1151 HOH A O   1 
HETATM 8091 O  O   . HOH BA 7 .   ? 43.45288 16.11186  -8.82421  1.000 28.51417 ? 1152 HOH A O   1 
HETATM 8092 O  O   . HOH BA 7 .   ? 2.90573  -19.70447 -7.12818  1.000 35.11281 ? 1153 HOH A O   1 
HETATM 8093 O  O   . HOH BA 7 .   ? 10.39541 -19.72341 -16.81546 1.000 36.68505 ? 1154 HOH A O   1 
HETATM 8094 O  O   . HOH BA 7 .   ? 9.83998  -13.98570 6.76629   1.000 42.16627 ? 1155 HOH A O   1 
HETATM 8095 O  O   . HOH BA 7 .   ? 29.97996 -36.84137 3.62557   1.000 41.41241 ? 1156 HOH A O   1 
HETATM 8096 O  O   . HOH BA 7 .   ? 9.30962  -0.19603  -32.72588 1.000 41.54455 ? 1157 HOH A O   1 
HETATM 8097 O  O   . HOH BA 7 .   ? 26.25008 11.56016  -4.70831  1.000 31.03307 ? 1158 HOH A O   1 
HETATM 8098 O  O   . HOH BA 7 .   ? 35.83707 -27.41930 -24.41654 1.000 50.30928 ? 1159 HOH A O   1 
HETATM 8099 O  O   . HOH BA 7 .   ? 44.24151 -25.69452 3.05238   1.000 32.46031 ? 1160 HOH A O   1 
HETATM 8100 O  O   . HOH BA 7 .   ? 20.20616 -24.20850 6.21303   1.000 35.50102 ? 1161 HOH A O   1 
HETATM 8101 O  O   . HOH BA 7 .   ? 33.94493 24.08219  -21.27975 1.000 39.72087 ? 1162 HOH A O   1 
HETATM 8102 O  O   . HOH BA 7 .   ? 28.10075 -35.69543 4.14044   1.000 41.50702 ? 1163 HOH A O   1 
HETATM 8103 O  O   . HOH BA 7 .   ? 19.67283 -25.80840 -26.21778 1.000 42.72027 ? 1164 HOH A O   1 
HETATM 8104 O  O   . HOH BA 7 .   ? 24.01042 -9.13642  -34.75057 1.000 44.35503 ? 1165 HOH A O   1 
HETATM 8105 O  O   . HOH BA 7 .   ? 30.46302 -32.65859 5.64295   1.000 41.49886 ? 1166 HOH A O   1 
HETATM 8106 O  O   A HOH BA 7 .   ? 29.26548 14.07852  -6.22158  0.539 25.06308 ? 1167 HOH A O   1 
HETATM 8107 O  O   B HOH BA 7 .   ? 29.25306 15.39087  -5.14552  0.461 28.69855 ? 1167 HOH A O   1 
HETATM 8108 O  O   . HOH BA 7 .   ? 56.69525 -10.06789 -8.78210  1.000 47.14458 ? 1168 HOH A O   1 
HETATM 8109 O  O   . HOH BA 7 .   ? 38.87289 -0.34801  -37.61359 1.000 55.46045 ? 1169 HOH A O   1 
HETATM 8110 O  O   . HOH BA 7 .   ? 22.36104 -24.13171 -27.90353 1.000 45.17399 ? 1170 HOH A O   1 
HETATM 8111 O  O   . HOH BA 7 .   ? 31.73988 24.14606  -17.00780 1.000 41.43848 ? 1171 HOH A O   1 
HETATM 8112 O  O   . HOH CA 7 .   ? 3.97999  11.23945  -3.32973  1.000 39.12667 ? 701  HOH B O   1 
HETATM 8113 O  O   . HOH CA 7 .   ? 25.52968 29.98480  -37.06203 1.000 46.45518 ? 702  HOH B O   1 
HETATM 8114 O  O   . HOH CA 7 .   ? 40.08326 21.04335  5.54386   1.000 37.61567 ? 703  HOH B O   1 
HETATM 8115 O  O   A HOH CA 7 .   ? 7.82316  55.41562  4.12529   0.362 27.12381 ? 704  HOH B O   1 
HETATM 8116 O  O   B HOH CA 7 .   ? 9.05386  54.82106  5.86334   0.638 29.36268 ? 704  HOH B O   1 
HETATM 8117 O  O   . HOH CA 7 .   ? 12.60133 32.75616  12.91345  1.000 37.12046 ? 705  HOH B O   1 
HETATM 8118 O  O   . HOH CA 7 .   ? 36.21727 20.29272  -4.11952  1.000 38.04080 ? 706  HOH B O   1 
HETATM 8119 O  O   . HOH CA 7 .   ? 10.77280 23.77980  -12.52324 1.000 25.22211 ? 707  HOH B O   1 
HETATM 8120 O  O   . HOH CA 7 .   ? 38.91591 34.33253  -17.74451 1.000 42.39305 ? 708  HOH B O   1 
HETATM 8121 O  O   . HOH CA 7 .   ? 26.53568 18.30730  -36.19539 1.000 42.57532 ? 709  HOH B O   1 
HETATM 8122 O  O   . HOH CA 7 .   ? 21.08768 61.17735  -8.10049  1.000 37.60300 ? 710  HOH B O   1 
HETATM 8123 O  O   . HOH CA 7 .   ? 44.08997 38.71382  5.49024   1.000 40.57055 ? 711  HOH B O   1 
HETATM 8124 O  O   . HOH CA 7 .   ? -6.16778 29.26246  -11.24347 1.000 38.84095 ? 712  HOH B O   1 
HETATM 8125 O  O   . HOH CA 7 .   ? 8.17478  52.76654  9.37815   1.000 42.15510 ? 713  HOH B O   1 
HETATM 8126 O  O   . HOH CA 7 .   ? 28.15854 50.91296  -7.71916  1.000 23.11149 ? 714  HOH B O   1 
HETATM 8127 O  O   . HOH CA 7 .   ? 4.19491  57.13844  -3.39972  1.000 43.55668 ? 715  HOH B O   1 
HETATM 8128 O  O   . HOH CA 7 .   ? 37.59480 41.12548  -15.19681 1.000 33.81122 ? 716  HOH B O   1 
HETATM 8129 O  O   . HOH CA 7 .   ? 19.92441 42.07154  11.34528  1.000 37.38613 ? 717  HOH B O   1 
HETATM 8130 O  O   . HOH CA 7 .   ? 47.37083 35.51750  -9.80152  1.000 41.90390 ? 718  HOH B O   1 
HETATM 8131 O  O   . HOH CA 7 .   ? 16.05402 -4.41363  -32.23838 1.000 38.04501 ? 719  HOH B O   1 
HETATM 8132 O  O   . HOH CA 7 .   ? 24.09618 23.17766  -26.41891 1.000 24.06555 ? 720  HOH B O   1 
HETATM 8133 O  O   . HOH CA 7 .   ? 28.74259 24.54670  -38.39033 1.000 40.65920 ? 721  HOH B O   1 
HETATM 8134 O  O   . HOH CA 7 .   ? 17.808   68.919    2.656     1.000 33.77748 ? 722  HOH B O   1 
HETATM 8135 O  O   . HOH CA 7 .   ? 12.99824 48.68296  -26.09812 1.000 40.19120 ? 723  HOH B O   1 
HETATM 8136 O  O   . HOH CA 7 .   ? 4.59628  6.50573   -21.50531 1.000 36.99165 ? 724  HOH B O   1 
HETATM 8137 O  O   . HOH CA 7 .   ? -2.47903 35.58300  -6.09811  1.000 39.97381 ? 725  HOH B O   1 
HETATM 8138 O  O   . HOH CA 7 .   ? 35.79005 37.65225  -15.87487 1.000 28.88614 ? 726  HOH B O   1 
HETATM 8139 O  O   . HOH CA 7 .   ? 21.13094 25.61162  10.07513  1.000 34.85980 ? 727  HOH B O   1 
HETATM 8140 O  O   . HOH CA 7 .   ? 37.76743 27.41868  13.76175  1.000 36.97469 ? 728  HOH B O   1 
HETATM 8141 O  O   . HOH CA 7 .   ? 14.22826 26.34550  2.71742   1.000 32.38756 ? 729  HOH B O   1 
HETATM 8142 O  O   . HOH CA 7 .   ? 5.53305  26.35941  -10.10129 1.000 32.44538 ? 730  HOH B O   1 
HETATM 8143 O  O   . HOH CA 7 .   ? 23.33590 16.07860  5.26890   1.000 46.27155 ? 731  HOH B O   1 
HETATM 8144 O  O   . HOH CA 7 .   ? 41.24675 24.41659  2.97546   1.000 36.51414 ? 732  HOH B O   1 
HETATM 8145 O  O   . HOH CA 7 .   ? 39.06473 50.91737  -5.06231  1.000 31.56101 ? 733  HOH B O   1 
HETATM 8146 O  O   . HOH CA 7 .   ? 29.48042 37.48380  9.80106   1.000 27.49650 ? 734  HOH B O   1 
HETATM 8147 O  O   . HOH CA 7 .   ? 8.19252  49.73165  10.84856  1.000 40.61135 ? 735  HOH B O   1 
HETATM 8148 O  O   . HOH CA 7 .   ? 18.59612 24.93641  -35.38258 1.000 27.03630 ? 736  HOH B O   1 
HETATM 8149 O  O   . HOH CA 7 .   ? 22.35070 16.20480  -18.60900 1.000 18.98049 ? 737  HOH B O   1 
HETATM 8150 O  O   . HOH CA 7 .   ? 4.51762  28.79115  5.64317   1.000 39.18529 ? 738  HOH B O   1 
HETATM 8151 O  O   . HOH CA 7 .   ? 7.28355  30.81924  -15.21068 1.000 20.40006 ? 739  HOH B O   1 
HETATM 8152 O  O   . HOH CA 7 .   ? 26.52636 37.64003  -8.00411  1.000 18.60843 ? 740  HOH B O   1 
HETATM 8153 O  O   . HOH CA 7 .   ? 8.69569  35.03896  -28.56259 1.000 38.31495 ? 741  HOH B O   1 
HETATM 8154 O  O   . HOH CA 7 .   ? 34.32462 18.67163  12.65000  1.000 44.34268 ? 742  HOH B O   1 
HETATM 8155 O  O   . HOH CA 7 .   ? 24.98223 27.56498  10.19115  1.000 28.69293 ? 743  HOH B O   1 
HETATM 8156 O  O   . HOH CA 7 .   ? 24.67765 30.39269  10.67902  1.000 23.53529 ? 744  HOH B O   1 
HETATM 8157 O  O   . HOH CA 7 .   ? 15.09968 28.16054  -29.87157 1.000 23.21615 ? 745  HOH B O   1 
HETATM 8158 O  O   . HOH CA 7 .   ? 2.40082  27.44443  -6.99967  1.000 23.59659 ? 746  HOH B O   1 
HETATM 8159 O  O   . HOH CA 7 .   ? 37.40329 35.02070  3.12730   1.000 20.85467 ? 747  HOH B O   1 
HETATM 8160 O  O   . HOH CA 7 .   ? 4.98758  35.43156  -20.27125 1.000 36.87006 ? 748  HOH B O   1 
HETATM 8161 O  O   . HOH CA 7 .   ? 5.67931  51.65860  -2.75470  1.000 31.11201 ? 749  HOH B O   1 
HETATM 8162 O  O   . HOH CA 7 .   ? 36.83847 49.04854  3.66347   1.000 34.06658 ? 750  HOH B O   1 
HETATM 8163 O  O   . HOH CA 7 .   ? 11.45555 30.89449  -13.33942 1.000 20.41738 ? 751  HOH B O   1 
HETATM 8164 O  O   . HOH CA 7 .   ? 32.89912 23.53731  -37.18963 1.000 38.05585 ? 752  HOH B O   1 
HETATM 8165 O  O   . HOH CA 7 .   ? 28.80044 18.24435  -34.49602 1.000 30.60371 ? 753  HOH B O   1 
HETATM 8166 O  O   . HOH CA 7 .   ? 34.27683 49.87941  -19.11199 1.000 32.08637 ? 754  HOH B O   1 
HETATM 8167 O  O   . HOH CA 7 .   ? 34.40102 47.48778  -22.76987 1.000 40.88067 ? 755  HOH B O   1 
HETATM 8168 O  O   . HOH CA 7 .   ? 3.06979  28.21234  -19.58936 1.000 32.09138 ? 756  HOH B O   1 
HETATM 8169 O  O   . HOH CA 7 .   ? 23.83101 15.83388  -11.36262 1.000 23.00372 ? 757  HOH B O   1 
HETATM 8170 O  O   . HOH CA 7 .   ? 10.04116 43.05337  -23.74030 1.000 25.31083 ? 758  HOH B O   1 
HETATM 8171 O  O   A HOH CA 7 .   ? 12.17379 53.10715  -18.74613 0.698 23.41310 ? 759  HOH B O   1 
HETATM 8172 O  O   B HOH CA 7 .   ? 10.89473 53.39425  -17.90392 0.302 25.09233 ? 759  HOH B O   1 
HETATM 8173 O  O   . HOH CA 7 .   ? 53.97193 41.68900  -12.00520 1.000 41.95743 ? 760  HOH B O   1 
HETATM 8174 O  O   . HOH CA 7 .   ? 32.22530 34.62502  -10.49679 1.000 19.62234 ? 761  HOH B O   1 
HETATM 8175 O  O   . HOH CA 7 .   ? 31.72153 32.96482  -19.09999 1.000 26.88857 ? 762  HOH B O   1 
HETATM 8176 O  O   A HOH CA 7 .   ? 2.95431  32.85333  -15.57136 0.534 35.53971 ? 763  HOH B O   1 
HETATM 8177 O  O   B HOH CA 7 .   ? 3.53445  34.62872  -15.16916 0.466 29.52240 ? 763  HOH B O   1 
HETATM 8178 O  O   . HOH CA 7 .   ? 18.62051 22.66891  2.86631   1.000 25.23994 ? 764  HOH B O   1 
HETATM 8179 O  O   . HOH CA 7 .   ? 7.73843  33.16672  -14.02910 1.000 22.74977 ? 765  HOH B O   1 
HETATM 8180 O  O   . HOH CA 7 .   ? 7.05831  15.65962  -29.32376 1.000 38.18695 ? 766  HOH B O   1 
HETATM 8181 O  O   . HOH CA 7 .   ? 2.627    44.633    6.533     1.000 33.80491 ? 767  HOH B O   1 
HETATM 8182 O  O   . HOH CA 7 .   ? 30.83423 40.91552  -24.68548 1.000 22.69794 ? 768  HOH B O   1 
HETATM 8183 O  O   . HOH CA 7 .   ? 3.54851  29.58386  2.44002   1.000 23.63247 ? 769  HOH B O   1 
HETATM 8184 O  O   . HOH CA 7 .   ? -0.54411 36.95267  -7.81036  1.000 41.89296 ? 770  HOH B O   1 
HETATM 8185 O  O   A HOH CA 7 .   ? 17.39789 14.13792  -0.97900  0.510 27.17661 ? 771  HOH B O   1 
HETATM 8186 O  O   B HOH CA 7 .   ? 18.47814 14.13527  -1.98119  0.490 25.99719 ? 771  HOH B O   1 
HETATM 8187 O  O   . HOH CA 7 .   ? 22.82586 64.60370  -6.96568  1.000 37.46061 ? 772  HOH B O   1 
HETATM 8188 O  O   . HOH CA 7 .   ? -0.96075 35.21615  -9.60131  1.000 34.92267 ? 773  HOH B O   1 
HETATM 8189 O  O   . HOH CA 7 .   ? 7.79805  11.68235  -6.36120  1.000 20.59151 ? 774  HOH B O   1 
HETATM 8190 O  O   . HOH CA 7 .   ? 42.63226 52.43752  -4.06586  1.000 43.52973 ? 775  HOH B O   1 
HETATM 8191 O  O   . HOH CA 7 .   ? 17.59085 56.27319  0.34189   1.000 27.89954 ? 776  HOH B O   1 
HETATM 8192 O  O   . HOH CA 7 .   ? 19.83857 5.16775   -21.36163 1.000 20.57818 ? 777  HOH B O   1 
HETATM 8193 O  O   . HOH CA 7 .   ? 34.27673 35.86551  -0.36089  1.000 18.43624 ? 778  HOH B O   1 
HETATM 8194 O  O   . HOH CA 7 .   ? 25.40787 40.04639  -12.77370 1.000 19.78951 ? 779  HOH B O   1 
HETATM 8195 O  O   . HOH CA 7 .   ? 16.64679 36.92255  -20.38172 1.000 21.37861 ? 780  HOH B O   1 
HETATM 8196 O  O   . HOH CA 7 .   ? 8.83622  43.38423  10.45096  1.000 26.63758 ? 781  HOH B O   1 
HETATM 8197 O  O   . HOH CA 7 .   ? 34.23070 36.05135  -18.48096 1.000 23.55295 ? 782  HOH B O   1 
HETATM 8198 O  O   . HOH CA 7 .   ? 8.48240  24.83046  -0.35926  1.000 21.64899 ? 783  HOH B O   1 
HETATM 8199 O  O   . HOH CA 7 .   ? -2.03804 31.88903  -10.72981 1.000 33.98483 ? 784  HOH B O   1 
HETATM 8200 O  O   . HOH CA 7 .   ? 17.38343 34.03057  -12.80799 1.000 17.16825 ? 785  HOH B O   1 
HETATM 8201 O  O   . HOH CA 7 .   ? 6.01073  43.78615  -27.14547 1.000 42.58041 ? 786  HOH B O   1 
HETATM 8202 O  O   . HOH CA 7 .   ? 2.77331  50.29510  -8.29617  1.000 37.97544 ? 787  HOH B O   1 
HETATM 8203 O  O   . HOH CA 7 .   ? 25.13679 20.48357  -14.68040 1.000 19.35934 ? 788  HOH B O   1 
HETATM 8204 O  O   . HOH CA 7 .   ? 3.97402  29.71298  -26.34746 1.000 38.60622 ? 789  HOH B O   1 
HETATM 8205 O  O   . HOH CA 7 .   ? 36.72736 45.80710  4.75799   1.000 32.97353 ? 790  HOH B O   1 
HETATM 8206 O  O   . HOH CA 7 .   ? 1.89825  22.02570  -0.74498  1.000 41.25563 ? 791  HOH B O   1 
HETATM 8207 O  O   . HOH CA 7 .   ? 19.98506 44.42354  -30.23308 1.000 48.38508 ? 792  HOH B O   1 
HETATM 8208 O  O   . HOH CA 7 .   ? 9.18622  39.38949  -14.90621 1.000 18.63953 ? 793  HOH B O   1 
HETATM 8209 O  O   . HOH CA 7 .   ? 5.37046  45.10203  -5.43596  1.000 28.04520 ? 794  HOH B O   1 
HETATM 8210 O  O   . HOH CA 7 .   ? 0.96665  39.78709  -5.28556  1.000 28.91233 ? 795  HOH B O   1 
HETATM 8211 O  O   . HOH CA 7 .   ? 30.71556 52.80432  -5.90489  1.000 29.05075 ? 796  HOH B O   1 
HETATM 8212 O  O   . HOH CA 7 .   ? 12.68611 28.51612  -13.02747 1.000 19.35896 ? 797  HOH B O   1 
HETATM 8213 O  O   . HOH CA 7 .   ? 31.94113 27.94626  -8.67666  1.000 18.97531 ? 798  HOH B O   1 
HETATM 8214 O  O   . HOH CA 7 .   ? -4.02277 15.59896  -14.13406 1.000 42.31185 ? 799  HOH B O   1 
HETATM 8215 O  O   . HOH CA 7 .   ? 29.45090 26.39291  -5.94952  1.000 16.59228 ? 800  HOH B O   1 
HETATM 8216 O  O   . HOH CA 7 .   ? 13.46077 2.87911   -21.10349 1.000 25.03336 ? 801  HOH B O   1 
HETATM 8217 O  O   . HOH CA 7 .   ? 16.96525 4.41687   -19.10599 1.000 23.62072 ? 802  HOH B O   1 
HETATM 8218 O  O   . HOH CA 7 .   ? 15.96085 17.46509  -6.06627  1.000 17.26727 ? 803  HOH B O   1 
HETATM 8219 O  O   . HOH CA 7 .   ? 10.22114 0.85960   -19.53933 1.000 37.93497 ? 804  HOH B O   1 
HETATM 8220 O  O   . HOH CA 7 .   ? 29.89457 46.42483  -21.13605 1.000 23.99486 ? 805  HOH B O   1 
HETATM 8221 O  O   . HOH CA 7 .   ? 4.12289  32.82995  4.53475   1.000 26.68962 ? 806  HOH B O   1 
HETATM 8222 O  O   . HOH CA 7 .   ? 13.60591 60.59026  -6.75696  1.000 35.62084 ? 807  HOH B O   1 
HETATM 8223 O  O   . HOH CA 7 .   ? 27.75708 52.18286  -27.10343 1.000 33.27994 ? 808  HOH B O   1 
HETATM 8224 O  O   . HOH CA 7 .   ? 28.03348 19.70413  9.95648   1.000 40.47258 ? 809  HOH B O   1 
HETATM 8225 O  O   . HOH CA 7 .   ? 10.95043 22.91678  -10.04532 1.000 21.50058 ? 810  HOH B O   1 
HETATM 8226 O  O   . HOH CA 7 .   ? 27.45210 24.37029  -24.42563 1.000 22.08789 ? 811  HOH B O   1 
HETATM 8227 O  O   . HOH CA 7 .   ? 8.56119  25.74856  5.52083   1.000 31.50703 ? 812  HOH B O   1 
HETATM 8228 O  O   . HOH CA 7 .   ? 11.09376 41.97478  7.34414   1.000 20.50491 ? 813  HOH B O   1 
HETATM 8229 O  O   . HOH CA 7 .   ? 42.10704 49.01621  -11.12844 1.000 32.47207 ? 814  HOH B O   1 
HETATM 8230 O  O   . HOH CA 7 .   ? 20.57032 24.43611  -5.20565  1.000 16.27595 ? 815  HOH B O   1 
HETATM 8231 O  O   . HOH CA 7 .   ? 13.06971 11.96373  -32.75832 1.000 35.90322 ? 816  HOH B O   1 
HETATM 8232 O  O   . HOH CA 7 .   ? 19.82959 35.59468  14.58782  1.000 37.09841 ? 817  HOH B O   1 
HETATM 8233 O  O   . HOH CA 7 .   ? 17.42155 15.68889  -20.72320 1.000 19.10410 ? 818  HOH B O   1 
HETATM 8234 O  O   . HOH CA 7 .   ? 39.67009 43.69572  3.57778   1.000 34.53297 ? 819  HOH B O   1 
HETATM 8235 O  O   . HOH CA 7 .   ? 3.20148  29.99285  -6.17129  1.000 19.27332 ? 820  HOH B O   1 
HETATM 8236 O  O   . HOH CA 7 .   ? 25.00539 37.14766  -20.67763 1.000 31.56758 ? 821  HOH B O   1 
HETATM 8237 O  O   . HOH CA 7 .   ? 20.70757 20.48628  6.64619   1.000 35.91023 ? 822  HOH B O   1 
HETATM 8238 O  O   . HOH CA 7 .   ? 3.64926  7.67121   -18.15190 1.000 37.10528 ? 823  HOH B O   1 
HETATM 8239 O  O   . HOH CA 7 .   ? 9.31196  -2.82768  -32.93181 1.000 45.17283 ? 824  HOH B O   1 
HETATM 8240 O  O   . HOH CA 7 .   ? 34.72193 30.69138  -20.81030 1.000 38.88494 ? 825  HOH B O   1 
HETATM 8241 O  O   . HOH CA 7 .   ? 14.88666 5.20404   -23.79785 1.000 26.78565 ? 826  HOH B O   1 
HETATM 8242 O  O   . HOH CA 7 .   ? 16.11552 27.64555  -17.89679 1.000 17.37012 ? 827  HOH B O   1 
HETATM 8243 O  O   . HOH CA 7 .   ? 32.57204 38.42663  -3.85332  1.000 18.33664 ? 828  HOH B O   1 
HETATM 8244 O  O   . HOH CA 7 .   ? 24.86780 16.32299  2.89018   1.000 44.21446 ? 829  HOH B O   1 
HETATM 8245 O  O   . HOH CA 7 .   ? 14.87836 26.64384  5.69929   1.000 37.26567 ? 830  HOH B O   1 
HETATM 8246 O  O   . HOH CA 7 .   ? 1.22510  24.76055  -4.32316  1.000 32.24302 ? 831  HOH B O   1 
HETATM 8247 O  O   . HOH CA 7 .   ? -3.37291 37.56085  -2.82580  1.000 37.99579 ? 832  HOH B O   1 
HETATM 8248 O  O   . HOH CA 7 .   ? 27.88011 21.77280  -11.47856 1.000 23.39244 ? 833  HOH B O   1 
HETATM 8249 O  O   . HOH CA 7 .   ? 22.97416 17.68401  -4.68095  1.000 18.79927 ? 834  HOH B O   1 
HETATM 8250 O  O   . HOH CA 7 .   ? 4.75445  13.55051  -26.53397 1.000 44.83294 ? 835  HOH B O   1 
HETATM 8251 O  O   . HOH CA 7 .   ? 44.50701 33.67783  -12.36465 1.000 46.27950 ? 836  HOH B O   1 
HETATM 8252 O  O   . HOH CA 7 .   ? 31.68407 20.04299  7.40674   1.000 32.23733 ? 837  HOH B O   1 
HETATM 8253 O  O   . HOH CA 7 .   ? 45.24953 36.00450  -8.52462  1.000 33.91312 ? 838  HOH B O   1 
HETATM 8254 O  O   . HOH CA 7 .   ? 34.43377 26.80758  -20.37285 1.000 39.15388 ? 839  HOH B O   1 
HETATM 8255 O  O   . HOH CA 7 .   ? 14.23873 27.99462  -1.83242  1.000 15.78060 ? 840  HOH B O   1 
HETATM 8256 O  O   . HOH CA 7 .   ? 10.74058 53.92788  7.77219   1.000 34.95995 ? 841  HOH B O   1 
HETATM 8257 O  O   . HOH CA 7 .   ? 3.87207  37.28556  -16.13719 1.000 40.64070 ? 842  HOH B O   1 
HETATM 8258 O  O   . HOH CA 7 .   ? 23.72385 34.76521  -21.17950 1.000 21.73502 ? 843  HOH B O   1 
HETATM 8259 O  O   . HOH CA 7 .   ? 19.72643 49.41175  -23.36669 1.000 35.54709 ? 844  HOH B O   1 
HETATM 8260 O  O   . HOH CA 7 .   ? 5.38063  35.51078  10.55151  1.000 35.41092 ? 845  HOH B O   1 
HETATM 8261 O  O   . HOH CA 7 .   ? 41.37878 31.96360  -11.68488 1.000 39.90947 ? 846  HOH B O   1 
HETATM 8262 O  O   . HOH CA 7 .   ? 30.15969 42.69655  -28.38359 1.000 26.61398 ? 847  HOH B O   1 
HETATM 8263 O  O   . HOH CA 7 .   ? 43.62655 36.13509  -6.10799  1.000 24.71591 ? 848  HOH B O   1 
HETATM 8264 O  O   . HOH CA 7 .   ? 17.34230 35.71661  -31.44329 1.000 35.07050 ? 849  HOH B O   1 
HETATM 8265 O  O   . HOH CA 7 .   ? 21.01489 16.20608  -1.54364  1.000 23.91828 ? 850  HOH B O   1 
HETATM 8266 O  O   . HOH CA 7 .   ? -3.40254 27.91139  -2.77385  1.000 33.63416 ? 851  HOH B O   1 
HETATM 8267 O  O   . HOH CA 7 .   ? 4.01297  3.96718   -22.69950 1.000 40.44828 ? 852  HOH B O   1 
HETATM 8268 O  O   . HOH CA 7 .   ? 15.25461 28.49117  8.73114   1.000 31.39450 ? 853  HOH B O   1 
HETATM 8269 O  O   . HOH CA 7 .   ? 30.24443 21.81381  -25.69819 1.000 24.93378 ? 854  HOH B O   1 
HETATM 8270 O  O   . HOH CA 7 .   ? 9.54063  13.22730  -32.38397 1.000 46.17254 ? 855  HOH B O   1 
HETATM 8271 O  O   . HOH CA 7 .   ? 6.721    52.191    1.586     1.000 39.78840 ? 856  HOH B O   1 
HETATM 8272 O  O   . HOH CA 7 .   ? 36.19908 46.73393  -17.46056 1.000 32.60396 ? 857  HOH B O   1 
HETATM 8273 O  O   . HOH CA 7 .   ? 35.94010 40.75357  -22.62962 1.000 30.21907 ? 858  HOH B O   1 
HETATM 8274 O  O   . HOH CA 7 .   ? 19.88972 9.17460   -22.19193 1.000 19.22288 ? 859  HOH B O   1 
HETATM 8275 O  O   . HOH CA 7 .   ? -1.59731 20.57841  -20.99647 1.000 40.30131 ? 860  HOH B O   1 
HETATM 8276 O  O   . HOH CA 7 .   ? 34.28515 54.31154  -4.91508  1.000 31.97213 ? 861  HOH B O   1 
HETATM 8277 O  O   . HOH CA 7 .   ? 17.26756 58.54187  -11.16977 1.000 36.12674 ? 862  HOH B O   1 
HETATM 8278 O  O   . HOH CA 7 .   ? 23.78995 25.26272  -21.93366 1.000 18.11519 ? 863  HOH B O   1 
HETATM 8279 O  O   . HOH CA 7 .   ? 29.60597 32.23300  -25.80959 1.000 24.22232 ? 864  HOH B O   1 
HETATM 8280 O  O   . HOH CA 7 .   ? 38.16160 38.95560  7.64523   1.000 29.44312 ? 865  HOH B O   1 
HETATM 8281 O  O   . HOH CA 7 .   ? 35.65387 26.12047  14.08779  1.000 35.46021 ? 866  HOH B O   1 
HETATM 8282 O  O   . HOH CA 7 .   ? 18.15261 16.16375  -33.08181 1.000 36.23484 ? 867  HOH B O   1 
HETATM 8283 O  O   . HOH CA 7 .   ? 20.04028 59.21180  -9.78626  1.000 36.40272 ? 868  HOH B O   1 
HETATM 8284 O  O   . HOH CA 7 .   ? 8.99829  30.28957  10.96123  1.000 39.28430 ? 869  HOH B O   1 
HETATM 8285 O  O   . HOH CA 7 .   ? 19.86002 59.08901  -12.78900 1.000 36.68100 ? 870  HOH B O   1 
HETATM 8286 O  O   . HOH CA 7 .   ? 37.64391 43.63038  -14.65829 1.000 29.45770 ? 871  HOH B O   1 
HETATM 8287 O  O   . HOH CA 7 .   ? 9.02484  29.82310  -1.75567  1.000 16.68758 ? 872  HOH B O   1 
HETATM 8288 O  O   . HOH CA 7 .   ? 25.06917 59.97455  3.83797   1.000 33.60972 ? 873  HOH B O   1 
HETATM 8289 O  O   . HOH CA 7 .   ? 23.25619 45.95987  12.99619  1.000 36.97480 ? 874  HOH B O   1 
HETATM 8290 O  O   . HOH CA 7 .   ? 27.08849 43.04406  13.45487  1.000 45.17979 ? 875  HOH B O   1 
HETATM 8291 O  O   . HOH CA 7 .   ? 32.347   52.536    2.272     1.000 27.89484 ? 876  HOH B O   1 
HETATM 8292 O  O   . HOH CA 7 .   ? 11.83622 33.70824  8.62629   1.000 20.56192 ? 877  HOH B O   1 
HETATM 8293 O  O   . HOH CA 7 .   ? -1.14501 36.07397  -11.99383 1.000 41.78696 ? 878  HOH B O   1 
HETATM 8294 O  O   . HOH CA 7 .   ? 26.63476 21.99833  -38.83994 1.000 32.63507 ? 879  HOH B O   1 
HETATM 8295 O  O   . HOH CA 7 .   ? 38.53610 47.44661  -16.18567 1.000 36.48749 ? 880  HOH B O   1 
HETATM 8296 O  O   . HOH CA 7 .   ? 32.22567 38.92990  -20.96686 1.000 24.54191 ? 881  HOH B O   1 
HETATM 8297 O  O   . HOH CA 7 .   ? 29.58780 38.35116  -32.72894 1.000 43.60596 ? 882  HOH B O   1 
HETATM 8298 O  O   . HOH CA 7 .   ? 4.48054  15.94309  -27.51346 1.000 46.51315 ? 883  HOH B O   1 
HETATM 8299 O  O   . HOH CA 7 .   ? 15.02323 40.66367  -26.23202 1.000 34.53567 ? 884  HOH B O   1 
HETATM 8300 O  O   . HOH CA 7 .   ? 18.20260 12.98647  -4.22589  1.000 24.86175 ? 885  HOH B O   1 
HETATM 8301 O  O   . HOH CA 7 .   ? 12.79469 61.01193  -4.07460  1.000 40.73671 ? 886  HOH B O   1 
HETATM 8302 O  O   . HOH CA 7 .   ? 33.69648 19.96225  -0.79320  1.000 37.73704 ? 887  HOH B O   1 
HETATM 8303 O  O   . HOH CA 7 .   ? 15.88645 46.08414  5.50017   1.000 20.11559 ? 888  HOH B O   1 
HETATM 8304 O  O   . HOH CA 7 .   ? 0.24265  18.96804  -12.31787 1.000 28.05120 ? 889  HOH B O   1 
HETATM 8305 O  O   . HOH CA 7 .   ? 0.289    50.818    3.205     1.000 24.79153 ? 890  HOH B O   1 
HETATM 8306 O  O   . HOH CA 7 .   ? 32.89935 41.54449  3.15233   1.000 19.82906 ? 891  HOH B O   1 
HETATM 8307 O  O   . HOH CA 7 .   ? 32.21003 27.30557  -5.88021  1.000 20.46337 ? 892  HOH B O   1 
HETATM 8308 O  O   . HOH CA 7 .   ? 30.04422 42.34177  10.07266  1.000 26.74554 ? 893  HOH B O   1 
HETATM 8309 O  O   . HOH CA 7 .   ? 36.87053 36.96987  10.17652  1.000 33.50682 ? 894  HOH B O   1 
HETATM 8310 O  O   . HOH CA 7 .   ? 36.71905 15.32627  2.13838   1.000 49.35210 ? 895  HOH B O   1 
HETATM 8311 O  O   . HOH CA 7 .   ? 6.58665  32.56350  -23.51508 1.000 29.61087 ? 896  HOH B O   1 
HETATM 8312 O  O   . HOH CA 7 .   ? 15.85726 16.51959  -24.61907 1.000 20.42526 ? 897  HOH B O   1 
HETATM 8313 O  O   . HOH CA 7 .   ? 8.74092  23.91040  -29.79703 1.000 30.06672 ? 898  HOH B O   1 
HETATM 8314 O  O   . HOH CA 7 .   ? 14.21734 12.06539  -27.18568 1.000 22.49559 ? 899  HOH B O   1 
HETATM 8315 O  O   . HOH CA 7 .   ? 21.985   65.518    2.427     1.000 37.44546 ? 900  HOH B O   1 
HETATM 8316 O  O   . HOH CA 7 .   ? 2.020    39.836    6.372     1.000 28.92102 ? 901  HOH B O   1 
HETATM 8317 O  O   . HOH CA 7 .   ? -2.84728 25.00340  -5.59578  1.000 34.91311 ? 902  HOH B O   1 
HETATM 8318 O  O   . HOH CA 7 .   ? 2.93397  26.47886  -9.44515  1.000 25.50078 ? 903  HOH B O   1 
HETATM 8319 O  O   . HOH CA 7 .   ? 8.67846  8.09801   -18.40196 1.000 23.45941 ? 904  HOH B O   1 
HETATM 8320 O  O   . HOH CA 7 .   ? 22.12135 41.03752  9.95777   1.000 23.96456 ? 905  HOH B O   1 
HETATM 8321 O  O   . HOH CA 7 .   ? 50.08084 36.62364  -8.18398  1.000 44.13402 ? 906  HOH B O   1 
HETATM 8322 O  O   . HOH CA 7 .   ? 18.11496 30.73418  10.66567  1.000 39.74384 ? 907  HOH B O   1 
HETATM 8323 O  O   . HOH CA 7 .   ? 23.10489 55.80752  -15.93303 1.000 29.61508 ? 908  HOH B O   1 
HETATM 8324 O  O   . HOH CA 7 .   ? 33.88611 29.70690  14.23442  1.000 36.80332 ? 909  HOH B O   1 
HETATM 8325 O  O   . HOH CA 7 .   ? 5.70717  37.44159  13.10398  1.000 37.35423 ? 910  HOH B O   1 
HETATM 8326 O  O   . HOH CA 7 .   ? 7.70080  12.86342  2.33781   1.000 46.56460 ? 911  HOH B O   1 
HETATM 8327 O  O   . HOH CA 7 .   ? 15.52376 29.97766  1.27305   1.000 18.48579 ? 912  HOH B O   1 
HETATM 8328 O  O   . HOH CA 7 .   ? -3.023   30.406    0.807     1.000 32.89064 ? 913  HOH B O   1 
HETATM 8329 O  O   . HOH CA 7 .   ? 16.03468 49.57860  -23.66318 1.000 34.20840 ? 914  HOH B O   1 
HETATM 8330 O  O   . HOH CA 7 .   ? 3.52027  24.54444  3.45025   1.000 41.38621 ? 915  HOH B O   1 
HETATM 8331 O  O   . HOH CA 7 .   ? 6.98360  22.02867  -2.10479  1.000 20.85200 ? 916  HOH B O   1 
HETATM 8332 O  O   . HOH CA 7 .   ? 35.64904 40.33710  -16.29318 1.000 31.27571 ? 917  HOH B O   1 
HETATM 8333 O  O   . HOH CA 7 .   ? 29.96835 40.31497  -20.08151 1.000 22.73387 ? 918  HOH B O   1 
HETATM 8334 O  O   . HOH CA 7 .   ? 5.76457  57.71593  -7.32974  1.000 44.18444 ? 919  HOH B O   1 
HETATM 8335 O  O   . HOH CA 7 .   ? 11.53970 42.52191  11.03670  1.000 28.52315 ? 920  HOH B O   1 
HETATM 8336 O  O   . HOH CA 7 .   ? 22.03572 35.01031  13.65573  1.000 28.79153 ? 921  HOH B O   1 
HETATM 8337 O  O   . HOH CA 7 .   ? 13.19022 12.95634  -1.75794  1.000 24.98109 ? 922  HOH B O   1 
HETATM 8338 O  O   . HOH CA 7 .   ? 26.74813 28.43961  -21.68950 1.000 21.43601 ? 923  HOH B O   1 
HETATM 8339 O  O   . HOH CA 7 .   ? 1.85875  42.82959  -4.93726  1.000 30.20904 ? 924  HOH B O   1 
HETATM 8340 O  O   . HOH CA 7 .   ? 40.02233 50.24568  1.54657   1.000 44.12733 ? 925  HOH B O   1 
HETATM 8341 O  O   . HOH CA 7 .   ? 15.88953 21.30459  -34.36117 1.000 26.64796 ? 926  HOH B O   1 
HETATM 8342 O  O   . HOH CA 7 .   ? 22.58795 32.66594  -25.98402 1.000 21.75102 ? 927  HOH B O   1 
HETATM 8343 O  O   . HOH CA 7 .   ? 3.84951  40.70992  -14.40355 1.000 34.83461 ? 928  HOH B O   1 
HETATM 8344 O  O   . HOH CA 7 .   ? 22.66066 41.89111  -28.41351 1.000 28.56461 ? 929  HOH B O   1 
HETATM 8345 O  O   A HOH CA 7 .   ? 31.09969 19.78071  -2.06856  0.452 28.41045 ? 930  HOH B O   1 
HETATM 8346 O  O   B HOH CA 7 .   ? 30.99318 19.43492  -0.31879  0.548 34.29685 ? 930  HOH B O   1 
HETATM 8347 O  O   . HOH CA 7 .   ? 11.26626 47.72927  -23.34490 1.000 37.91620 ? 931  HOH B O   1 
HETATM 8348 O  O   . HOH CA 7 .   ? 29.49753 52.39185  -22.29032 1.000 31.46515 ? 932  HOH B O   1 
HETATM 8349 O  O   . HOH CA 7 .   ? 30.82031 54.00115  -18.40475 1.000 35.92598 ? 933  HOH B O   1 
HETATM 8350 O  O   . HOH CA 7 .   ? 2.40922  26.89108  -21.90659 1.000 31.16936 ? 934  HOH B O   1 
HETATM 8351 O  O   . HOH CA 7 .   ? 24.85085 44.30984  11.73071  1.000 34.53392 ? 935  HOH B O   1 
HETATM 8352 O  O   . HOH CA 7 .   ? 21.28328 27.04417  -4.25328  1.000 15.71448 ? 936  HOH B O   1 
HETATM 8353 O  O   . HOH CA 7 .   ? 10.01073 54.29418  -15.02197 1.000 30.36700 ? 937  HOH B O   1 
HETATM 8354 O  O   . HOH CA 7 .   ? 35.21846 53.53765  -1.43042  1.000 35.02165 ? 938  HOH B O   1 
HETATM 8355 O  O   . HOH CA 7 .   ? 10.93834 39.81083  -27.76492 1.000 47.31137 ? 939  HOH B O   1 
HETATM 8356 O  O   . HOH CA 7 .   ? 20.53645 29.31064  11.28511  1.000 43.07420 ? 940  HOH B O   1 
HETATM 8357 O  O   . HOH CA 7 .   ? 16.18954 42.71217  11.29761  1.000 36.86976 ? 941  HOH B O   1 
HETATM 8358 O  O   . HOH CA 7 .   ? 41.39632 28.53220  13.93597  1.000 42.28464 ? 942  HOH B O   1 
HETATM 8359 O  O   . HOH CA 7 .   ? 56.64436 39.20864  -17.27226 1.000 52.47877 ? 943  HOH B O   1 
HETATM 8360 O  O   . HOH CA 7 .   ? 21.42698 26.55314  -21.70145 1.000 18.75434 ? 944  HOH B O   1 
HETATM 8361 O  O   . HOH CA 7 .   ? -0.15260 20.65494  -10.45615 1.000 32.38677 ? 945  HOH B O   1 
HETATM 8362 O  O   . HOH CA 7 .   ? 3.78420  30.66236  -15.76537 1.000 34.85770 ? 946  HOH B O   1 
HETATM 8363 O  O   . HOH CA 7 .   ? 21.57276 54.12636  -18.40586 1.000 29.51339 ? 947  HOH B O   1 
HETATM 8364 O  O   . HOH CA 7 .   ? 24.04828 44.38508  -20.80109 1.000 21.55446 ? 948  HOH B O   1 
HETATM 8365 O  O   . HOH CA 7 .   ? 16.00586 43.01134  -29.39715 1.000 48.06924 ? 949  HOH B O   1 
HETATM 8366 O  O   . HOH CA 7 .   ? 3.247    44.449    13.600    1.000 41.30603 ? 950  HOH B O   1 
HETATM 8367 O  O   . HOH CA 7 .   ? 31.91075 20.29967  10.02874  1.000 38.53100 ? 951  HOH B O   1 
HETATM 8368 O  O   . HOH CA 7 .   ? 3.86914  46.47396  -21.59085 1.000 44.34755 ? 952  HOH B O   1 
HETATM 8369 O  O   . HOH CA 7 .   ? 23.88549 58.89496  -13.83054 1.000 42.79425 ? 953  HOH B O   1 
HETATM 8370 O  O   . HOH CA 7 .   ? 5.61566  33.09384  -17.49586 1.000 40.42924 ? 954  HOH B O   1 
HETATM 8371 O  O   . HOH CA 7 .   ? 13.70503 53.62063  6.80291   1.000 26.36055 ? 955  HOH B O   1 
HETATM 8372 O  O   . HOH CA 7 .   ? 13.28582 39.81242  -12.39953 1.000 17.56761 ? 956  HOH B O   1 
HETATM 8373 O  O   . HOH CA 7 .   ? 9.53885  20.91052  -2.40269  1.000 18.52882 ? 957  HOH B O   1 
HETATM 8374 O  O   . HOH CA 7 .   ? 33.72746 42.97065  7.89130   1.000 36.83316 ? 958  HOH B O   1 
HETATM 8375 O  O   . HOH CA 7 .   ? 17.07264 30.12804  -27.17100 1.000 25.80922 ? 959  HOH B O   1 
HETATM 8376 O  O   . HOH CA 7 .   ? 15.00771 12.17691  -16.81768 1.000 19.13153 ? 960  HOH B O   1 
HETATM 8377 O  O   . HOH CA 7 .   ? 34.15068 18.17083  8.20901   1.000 39.66698 ? 961  HOH B O   1 
HETATM 8378 O  O   . HOH CA 7 .   ? 14.25788 8.69038   -15.84236 1.000 23.36881 ? 962  HOH B O   1 
HETATM 8379 O  O   . HOH CA 7 .   ? 13.45774 55.47165  0.41488   1.000 37.60583 ? 963  HOH B O   1 
HETATM 8380 O  O   . HOH CA 7 .   ? 26.71287 35.46780  -20.13169 1.000 21.96793 ? 964  HOH B O   1 
HETATM 8381 O  O   . HOH CA 7 .   ? 18.17825 17.79525  -29.93523 1.000 35.43306 ? 965  HOH B O   1 
HETATM 8382 O  O   . HOH CA 7 .   ? 0.60563  10.64429  -25.82077 1.000 50.80648 ? 966  HOH B O   1 
HETATM 8383 O  O   . HOH CA 7 .   ? 4.644    39.306    6.340     1.000 32.72727 ? 967  HOH B O   1 
HETATM 8384 O  O   . HOH CA 7 .   ? 22.80720 14.53721  -6.59097  1.000 22.71030 ? 968  HOH B O   1 
HETATM 8385 O  O   . HOH CA 7 .   ? 32.13005 36.32039  -20.17682 1.000 24.02796 ? 969  HOH B O   1 
HETATM 8386 O  O   . HOH CA 7 .   ? 24.88127 18.53287  -2.94345  1.000 21.75009 ? 970  HOH B O   1 
HETATM 8387 O  O   . HOH CA 7 .   ? 10.41106 27.28767  -30.94221 1.000 39.39986 ? 971  HOH B O   1 
HETATM 8388 O  O   . HOH CA 7 .   ? 40.85514 26.72658  9.89845   1.000 34.91988 ? 972  HOH B O   1 
HETATM 8389 O  O   . HOH CA 7 .   ? 13.03965 36.59256  14.65915  1.000 45.21147 ? 973  HOH B O   1 
HETATM 8390 O  O   . HOH CA 7 .   ? 53.750   37.544    -27.663   1.000 46.85280 ? 974  HOH B O   1 
HETATM 8391 O  O   . HOH CA 7 .   ? 34.15601 45.80447  3.72943   1.000 31.14466 ? 975  HOH B O   1 
HETATM 8392 O  O   . HOH CA 7 .   ? 22.28648 13.97625  -13.36200 1.000 29.00620 ? 976  HOH B O   1 
HETATM 8393 O  O   . HOH CA 7 .   ? 45.19583 41.56573  -1.63513  1.000 24.10589 ? 977  HOH B O   1 
HETATM 8394 O  O   . HOH CA 7 .   ? 10.76553 37.02350  -27.77161 1.000 38.91488 ? 978  HOH B O   1 
HETATM 8395 O  O   . HOH CA 7 .   ? 21.02372 15.77488  -31.58950 1.000 40.44616 ? 979  HOH B O   1 
HETATM 8396 O  O   . HOH CA 7 .   ? 11.60739 29.61377  10.16208  1.000 38.88417 ? 980  HOH B O   1 
HETATM 8397 O  O   . HOH CA 7 .   ? 5.39482  5.50608   -11.63883 1.000 37.00968 ? 981  HOH B O   1 
HETATM 8398 O  O   . HOH CA 7 .   ? 6.08933  -0.84381  -28.43511 1.000 44.61863 ? 982  HOH B O   1 
HETATM 8399 O  O   . HOH CA 7 .   ? 38.29231 24.34837  -6.67809  1.000 37.75332 ? 983  HOH B O   1 
HETATM 8400 O  O   . HOH CA 7 .   ? 27.37138 20.63759  -16.68502 1.000 31.49707 ? 984  HOH B O   1 
HETATM 8401 O  O   . HOH CA 7 .   ? 34.75608 34.45531  -9.57561  1.000 18.82677 ? 985  HOH B O   1 
HETATM 8402 O  O   . HOH CA 7 .   ? 11.17403 20.12179  -33.11261 1.000 33.35119 ? 986  HOH B O   1 
HETATM 8403 O  O   . HOH CA 7 .   ? 31.18864 30.15054  -18.76826 1.000 25.14609 ? 987  HOH B O   1 
HETATM 8404 O  O   . HOH CA 7 .   ? 16.71415 7.54499   -15.92577 1.000 36.14380 ? 988  HOH B O   1 
HETATM 8405 O  O   . HOH CA 7 .   ? 33.22605 19.88409  -3.38674  1.000 34.25636 ? 989  HOH B O   1 
HETATM 8406 O  O   . HOH CA 7 .   ? 29.14994 52.50728  8.04431   1.000 45.11285 ? 990  HOH B O   1 
HETATM 8407 O  O   . HOH CA 7 .   ? 33.07490 37.35338  -28.69772 1.000 30.40864 ? 991  HOH B O   1 
HETATM 8408 O  O   . HOH CA 7 .   ? 6.67772  -1.92044  -23.77082 1.000 30.64856 ? 992  HOH B O   1 
HETATM 8409 O  O   . HOH CA 7 .   ? 11.72962 5.84217   -9.30410  1.000 32.01962 ? 993  HOH B O   1 
HETATM 8410 O  O   . HOH CA 7 .   ? -0.86889 25.22164  -8.25123  1.000 25.50950 ? 994  HOH B O   1 
HETATM 8411 O  O   . HOH CA 7 .   ? -0.47009 20.68254  -6.66271  1.000 25.31651 ? 995  HOH B O   1 
HETATM 8412 O  O   . HOH CA 7 .   ? 42.47601 30.73734  0.06290   1.000 31.00571 ? 996  HOH B O   1 
HETATM 8413 O  O   . HOH CA 7 .   ? 4.59159  9.90570   -26.33201 1.000 30.32968 ? 997  HOH B O   1 
HETATM 8414 O  O   . HOH CA 7 .   ? 3.44427  23.40523  -3.78238  1.000 25.09532 ? 998  HOH B O   1 
HETATM 8415 O  O   . HOH CA 7 .   ? 1.88074  21.13918  -26.69762 1.000 36.09601 ? 999  HOH B O   1 
HETATM 8416 O  O   . HOH CA 7 .   ? 44.58496 43.69084  -12.31513 1.000 34.22296 ? 1000 HOH B O   1 
HETATM 8417 O  O   . HOH CA 7 .   ? 35.86425 44.17292  -16.52745 1.000 29.34298 ? 1001 HOH B O   1 
HETATM 8418 O  O   . HOH CA 7 .   ? 22.02038 19.78037  -41.75196 1.000 37.90857 ? 1002 HOH B O   1 
HETATM 8419 O  O   . HOH CA 7 .   ? 57.35889 40.28011  -24.12074 1.000 44.48776 ? 1003 HOH B O   1 
HETATM 8420 O  O   . HOH CA 7 .   ? 5.22822  31.68445  8.16978   1.000 31.06837 ? 1004 HOH B O   1 
HETATM 8421 O  O   . HOH CA 7 .   ? 26.98736 44.14729  -10.89385 1.000 26.09544 ? 1005 HOH B O   1 
HETATM 8422 O  O   . HOH CA 7 .   ? 6.59790  3.77461   -28.57144 1.000 28.08073 ? 1006 HOH B O   1 
HETATM 8423 O  O   . HOH CA 7 .   ? 14.11881 43.53827  11.13727  1.000 34.58099 ? 1007 HOH B O   1 
HETATM 8424 O  O   A HOH CA 7 .   ? 7.03488  5.53194   -12.98840 0.601 27.64525 ? 1008 HOH B O   1 
HETATM 8425 O  O   B HOH CA 7 .   ? 8.26655  5.29341   -14.08813 0.399 29.49278 ? 1008 HOH B O   1 
HETATM 8426 O  O   . HOH CA 7 .   ? 43.42368 29.75077  -6.51134  1.000 33.56791 ? 1009 HOH B O   1 
HETATM 8427 O  O   . HOH CA 7 .   ? 15.66822 36.22141  15.17140  1.000 47.61825 ? 1010 HOH B O   1 
HETATM 8428 O  O   A HOH CA 7 .   ? 10.24647 16.00619  0.38097   0.647 20.53309 ? 1011 HOH B O   1 
HETATM 8429 O  O   B HOH CA 7 .   ? 10.96717 14.97366  0.60565   0.353 21.08955 ? 1011 HOH B O   1 
HETATM 8430 O  O   . HOH CA 7 .   ? 3.31930  50.23000  -16.29457 1.000 40.32968 ? 1012 HOH B O   1 
HETATM 8431 O  O   . HOH CA 7 .   ? 12.13192 55.65294  2.55890   1.000 37.65291 ? 1013 HOH B O   1 
HETATM 8432 O  O   . HOH CA 7 .   ? 40.77232 25.25105  -1.20523  1.000 36.03930 ? 1014 HOH B O   1 
HETATM 8433 O  O   . HOH CA 7 .   ? 7.51922  53.93232  -23.45533 1.000 45.56096 ? 1015 HOH B O   1 
HETATM 8434 O  O   . HOH CA 7 .   ? 38.73195 18.94503  -1.09150  1.000 42.85290 ? 1016 HOH B O   1 
HETATM 8435 O  O   . HOH CA 7 .   ? 22.64203 32.33210  13.11077  1.000 37.80642 ? 1017 HOH B O   1 
HETATM 8436 O  O   . HOH CA 7 .   ? 4.14645  41.10766  -19.98979 1.000 35.91842 ? 1018 HOH B O   1 
HETATM 8437 O  O   . HOH CA 7 .   ? 1.85799  40.58161  -11.61534 1.000 33.55831 ? 1019 HOH B O   1 
HETATM 8438 O  O   . HOH CA 7 .   ? 40.52922 50.22133  -2.59059  1.000 37.76358 ? 1020 HOH B O   1 
HETATM 8439 O  O   . HOH CA 7 .   ? 9.40602  9.09060   -20.96769 1.000 20.23222 ? 1021 HOH B O   1 
HETATM 8440 O  O   . HOH CA 7 .   ? 30.58059 34.70383  -26.33707 1.000 25.96151 ? 1022 HOH B O   1 
HETATM 8441 O  O   . HOH CA 7 .   ? 0.50155  16.66033  -2.84744  1.000 33.28352 ? 1023 HOH B O   1 
HETATM 8442 O  O   . HOH CA 7 .   ? 44.38699 33.06653  -3.04831  1.000 37.39079 ? 1024 HOH B O   1 
HETATM 8443 O  O   . HOH CA 7 .   ? 3.78963  37.74215  -20.40320 1.000 46.39397 ? 1025 HOH B O   1 
HETATM 8444 O  O   . HOH CA 7 .   ? 29.29505 49.99036  8.54249   1.000 42.94432 ? 1026 HOH B O   1 
HETATM 8445 O  O   . HOH CA 7 .   ? 39.81592 49.29439  -15.28497 1.000 37.94438 ? 1027 HOH B O   1 
HETATM 8446 O  O   . HOH CA 7 .   ? -2.524   31.105    4.922     1.000 33.64483 ? 1028 HOH B O   1 
HETATM 8447 O  O   . HOH CA 7 .   ? 21.79784 54.78256  -21.38479 1.000 46.66901 ? 1029 HOH B O   1 
HETATM 8448 O  O   . HOH CA 7 .   ? 2.35376  45.48392  -1.51012  1.000 42.25653 ? 1030 HOH B O   1 
HETATM 8449 O  O   . HOH CA 7 .   ? 13.54327 24.14141  1.26377   1.000 29.56324 ? 1031 HOH B O   1 
HETATM 8450 O  O   . HOH CA 7 .   ? 32.87158 58.03881  -11.32892 1.000 35.97965 ? 1032 HOH B O   1 
HETATM 8451 O  O   . HOH CA 7 .   ? 34.84423 39.84286  -20.33109 1.000 27.22526 ? 1033 HOH B O   1 
HETATM 8452 O  O   . HOH CA 7 .   ? 7.55022  21.51284  -30.64573 1.000 43.59311 ? 1034 HOH B O   1 
HETATM 8453 O  O   . HOH CA 7 .   ? 15.02668 55.35421  3.40714   1.000 40.24098 ? 1035 HOH B O   1 
HETATM 8454 O  O   . HOH CA 7 .   ? 29.41161 39.92795  11.37294  1.000 37.02036 ? 1036 HOH B O   1 
HETATM 8455 O  O   . HOH CA 7 .   ? 35.96278 56.19947  -2.62564  1.000 44.41824 ? 1037 HOH B O   1 
HETATM 8456 O  O   . HOH CA 7 .   ? 32.49858 49.46750  -29.55718 1.000 32.87797 ? 1038 HOH B O   1 
HETATM 8457 O  O   . HOH CA 7 .   ? 18.42187 32.03892  -25.95277 1.000 25.75618 ? 1039 HOH B O   1 
HETATM 8458 O  O   . HOH CA 7 .   ? 41.77991 42.62660  2.26381   1.000 34.95020 ? 1040 HOH B O   1 
HETATM 8459 O  O   . HOH CA 7 .   ? 14.76792 33.89793  -33.48078 1.000 36.65725 ? 1041 HOH B O   1 
HETATM 8460 O  O   . HOH CA 7 .   ? 44.61679 36.23248  3.85797   1.000 31.10772 ? 1042 HOH B O   1 
HETATM 8461 O  O   . HOH CA 7 .   ? 21.75210 44.71687  -28.63927 1.000 27.18111 ? 1043 HOH B O   1 
HETATM 8462 O  O   A HOH CA 7 .   ? 15.65339 14.40403  -27.32360 0.463 21.63353 ? 1044 HOH B O   1 
HETATM 8463 O  O   B HOH CA 7 .   ? 16.56352 13.31672  -28.62235 0.537 28.19714 ? 1044 HOH B O   1 
HETATM 8464 O  O   . HOH CA 7 .   ? 39.46074 26.82690  -7.13523  1.000 27.36238 ? 1045 HOH B O   1 
HETATM 8465 O  O   . HOH CA 7 .   ? 10.94729 24.04652  4.82917   1.000 38.26546 ? 1046 HOH B O   1 
HETATM 8466 O  O   . HOH CA 7 .   ? 0.50866  39.13676  -9.30347  1.000 43.96804 ? 1047 HOH B O   1 
HETATM 8467 O  O   . HOH CA 7 .   ? 21.21019 34.38989  -33.78267 1.000 46.48011 ? 1048 HOH B O   1 
HETATM 8468 O  O   . HOH CA 7 .   ? 7.94323  32.65542  -21.15591 1.000 27.37473 ? 1049 HOH B O   1 
HETATM 8469 O  O   . HOH CA 7 .   ? 6.53103  58.78038  -3.04171  1.000 42.36298 ? 1050 HOH B O   1 
HETATM 8470 O  O   . HOH CA 7 .   ? 31.79689 26.57466  -11.19749 1.000 22.56988 ? 1051 HOH B O   1 
HETATM 8471 O  O   A HOH CA 7 .   ? -3.27258 9.47563   -15.04280 0.395 25.18306 ? 1052 HOH B O   1 
HETATM 8472 O  O   B HOH CA 7 .   ? -2.92125 11.06379  -13.98556 0.605 23.27707 ? 1052 HOH B O   1 
HETATM 8473 O  O   . HOH CA 7 .   ? 33.42855 38.98520  12.07068  1.000 49.01628 ? 1053 HOH B O   1 
HETATM 8474 O  O   . HOH CA 7 .   ? 28.05086 19.86393  5.32366   1.000 41.51136 ? 1054 HOH B O   1 
HETATM 8475 O  O   . HOH CA 7 .   ? 2.75396  48.26931  -23.07288 1.000 47.13570 ? 1055 HOH B O   1 
HETATM 8476 O  O   . HOH CA 7 .   ? 12.61231 22.33262  -32.59295 1.000 28.74418 ? 1056 HOH B O   1 
HETATM 8477 O  O   . HOH CA 7 .   ? 4.51857  53.84268  -1.81923  1.000 41.62470 ? 1057 HOH B O   1 
HETATM 8478 O  O   . HOH CA 7 .   ? -2.96765 14.34530  -20.63352 1.000 43.49855 ? 1058 HOH B O   1 
HETATM 8479 O  O   A HOH CA 7 .   ? 16.15082 16.87929  -28.10193 0.641 21.55489 ? 1059 HOH B O   1 
HETATM 8480 O  O   B HOH CA 7 .   ? 16.77691 18.04997  -28.30125 0.359 22.20748 ? 1059 HOH B O   1 
HETATM 8481 O  O   A HOH CA 7 .   ? 1.97182  28.36419  4.56229   0.488 29.42247 ? 1060 HOH B O   1 
HETATM 8482 O  O   B HOH CA 7 .   ? 1.78690  27.48094  3.10961   0.512 33.43097 ? 1060 HOH B O   1 
HETATM 8483 O  O   . HOH CA 7 .   ? 9.19496  19.74827  0.80706   1.000 41.53972 ? 1061 HOH B O   1 
HETATM 8484 O  O   . HOH CA 7 .   ? -1.55501 4.03436   -14.56193 1.000 49.38106 ? 1062 HOH B O   1 
HETATM 8485 O  O   . HOH CA 7 .   ? 18.46942 43.47538  12.91960  1.000 42.45430 ? 1063 HOH B O   1 
HETATM 8486 O  O   . HOH CA 7 .   ? 25.82200 57.18496  -14.92579 1.000 41.57600 ? 1064 HOH B O   1 
HETATM 8487 O  O   . HOH CA 7 .   ? 25.168   62.840    -9.380    1.000 49.67325 ? 1065 HOH B O   1 
HETATM 8488 O  O   . HOH CA 7 .   ? 37.40700 42.33880  -27.65325 1.000 34.00547 ? 1066 HOH B O   1 
HETATM 8489 O  O   . HOH CA 7 .   ? -4.52489 22.50000  -11.92721 1.000 49.96452 ? 1067 HOH B O   1 
HETATM 8490 O  O   . HOH CA 7 .   ? 40.98281 55.00374  -7.34788  1.000 48.93324 ? 1068 HOH B O   1 
HETATM 8491 O  O   . HOH CA 7 .   ? -0.12553 7.38873   -21.35679 1.000 47.40344 ? 1069 HOH B O   1 
HETATM 8492 O  O   . HOH CA 7 .   ? 16.91913 38.11498  -29.25828 1.000 38.72129 ? 1070 HOH B O   1 
HETATM 8493 O  O   . HOH CA 7 .   ? 16.55380 39.86707  16.02657  1.000 47.84331 ? 1071 HOH B O   1 
HETATM 8494 O  O   . HOH CA 7 .   ? 29.54873 19.12312  1.92926   1.000 39.86219 ? 1072 HOH B O   1 
HETATM 8495 O  O   . HOH CA 7 .   ? 6.89245  57.19419  -9.64495  1.000 45.54602 ? 1073 HOH B O   1 
HETATM 8496 O  O   . HOH CA 7 .   ? 30.53859 25.26076  -13.69900 1.000 29.38164 ? 1074 HOH B O   1 
HETATM 8497 O  O   . HOH CA 7 .   ? 1.45359  9.39699   -4.60990  1.000 50.60116 ? 1075 HOH B O   1 
HETATM 8498 O  O   . HOH CA 7 .   ? 40.195   17.392    2.020     1.000 43.71830 ? 1076 HOH B O   1 
HETATM 8499 O  O   . HOH CA 7 .   ? 26.42256 14.69312  -32.11150 1.000 38.40962 ? 1077 HOH B O   1 
HETATM 8500 O  O   . HOH CA 7 .   ? 11.36955 60.70129  -7.81473  1.000 41.44137 ? 1078 HOH B O   1 
HETATM 8501 O  O   . HOH CA 7 .   ? 43.25914 25.93218  6.52970   1.000 39.64945 ? 1079 HOH B O   1 
HETATM 8502 O  O   . HOH CA 7 .   ? 26.45506 48.60458  -32.50701 1.000 43.24997 ? 1080 HOH B O   1 
HETATM 8503 O  O   A HOH CA 7 .   ? 4.73663  47.67049  -12.37450 0.574 35.20288 ? 1081 HOH B O   1 
HETATM 8504 O  O   B HOH CA 7 .   ? 4.37036  45.60789  -11.61668 0.426 27.25074 ? 1081 HOH B O   1 
HETATM 8505 O  O   . HOH CA 7 .   ? 24.01524 16.75141  -0.79948  1.000 34.92026 ? 1082 HOH B O   1 
HETATM 8506 O  O   . HOH CA 7 .   ? 52.50501 35.97056  -14.00088 1.000 48.53211 ? 1083 HOH B O   1 
HETATM 8507 O  O   A HOH CA 7 .   ? 21.23037 51.14635  -23.83405 0.417 30.52094 ? 1084 HOH B O   1 
HETATM 8508 O  O   B HOH CA 7 .   ? 22.86426 50.69438  -24.78968 0.583 27.35021 ? 1084 HOH B O   1 
HETATM 8509 O  O   . HOH CA 7 .   ? 8.02013  55.94419  -13.92974 1.000 35.76762 ? 1085 HOH B O   1 
HETATM 8510 O  O   . HOH CA 7 .   ? 9.88553  6.29069   -16.77407 1.000 38.18426 ? 1086 HOH B O   1 
HETATM 8511 O  O   A HOH CA 7 .   ? 12.51877 5.91223   -13.61809 0.511 29.74212 ? 1087 HOH B O   1 
HETATM 8512 O  O   B HOH CA 7 .   ? 13.00605 6.17675   -15.69444 0.489 28.83600 ? 1087 HOH B O   1 
HETATM 8513 O  O   A HOH CA 7 .   ? 9.86635  22.33617  0.73735   0.392 26.97415 ? 1088 HOH B O   1 
HETATM 8514 O  O   B HOH CA 7 .   ? 11.20548 23.00701  1.99911   0.608 27.83060 ? 1088 HOH B O   1 
HETATM 8515 O  O   . HOH CA 7 .   ? -4.314   19.046    -9.395    1.000 24.45771 ? 1089 HOH B O   1 
HETATM 8516 O  O   . HOH CA 7 .   ? 21.52565 47.17721  -31.19665 1.000 48.61165 ? 1090 HOH B O   1 
HETATM 8517 O  O   . HOH CA 7 .   ? 25.19726 38.12320  -31.46952 1.000 42.96220 ? 1091 HOH B O   1 
HETATM 8518 O  O   . HOH CA 7 .   ? 1.45078  37.21698  -14.89157 1.000 42.17441 ? 1092 HOH B O   1 
HETATM 8519 O  O   . HOH CA 7 .   ? -0.69502 43.39083  -6.35066  1.000 48.98010 ? 1093 HOH B O   1 
HETATM 8520 O  O   . HOH CA 7 .   ? 21.147   67.828    3.860     1.000 32.90350 ? 1094 HOH B O   1 
HETATM 8521 O  O   . HOH CA 7 .   ? 15.71038 12.71133  -0.49298  1.000 42.57130 ? 1095 HOH B O   1 
HETATM 8522 O  O   . HOH CA 7 .   ? 14.61619 38.87058  -28.33172 1.000 40.53873 ? 1096 HOH B O   1 
HETATM 8523 O  O   . HOH CA 7 .   ? 29.67886 21.27484  11.66080  1.000 43.13994 ? 1097 HOH B O   1 
HETATM 8524 O  O   A HOH CA 7 .   ? -3.70241 30.57488  -2.14712  0.670 19.15965 ? 1098 HOH B O   1 
HETATM 8525 O  O   B HOH CA 7 .   ? -4.21027 31.58025  -3.30269  0.330 21.94669 ? 1098 HOH B O   1 
HETATM 8526 O  O   . HOH CA 7 .   ? 1.48993  11.92066  -4.54500  1.000 40.16359 ? 1099 HOH B O   1 
HETATM 8527 O  O   . HOH CA 7 .   ? 0.792    46.249    5.900     1.000 41.32180 ? 1100 HOH B O   1 
HETATM 8528 O  O   . HOH CA 7 .   ? 5.85158  35.06409  -24.35796 1.000 41.95670 ? 1101 HOH B O   1 
HETATM 8529 O  O   A HOH CA 7 .   ? 1.18155  27.84386  -17.05780 0.638 18.27666 ? 1102 HOH B O   1 
HETATM 8530 O  O   B HOH CA 7 .   ? 1.89525  28.73946  -16.87203 0.362 19.30384 ? 1102 HOH B O   1 
HETATM 8531 O  O   . HOH CA 7 .   ? 13.67475 48.76809  11.23778  1.000 39.89948 ? 1103 HOH B O   1 
HETATM 8532 O  O   A HOH CA 7 .   ? -2.695   18.179    -6.598    0.730 27.34495 ? 1104 HOH B O   1 
HETATM 8533 O  O   B HOH CA 7 .   ? -1.755   18.803    -5.380    0.270 27.60149 ? 1104 HOH B O   1 
HETATM 8534 O  O   . HOH CA 7 .   ? 46.37002 35.08567  -17.65374 1.000 29.55526 ? 1105 HOH B O   1 
HETATM 8535 O  O   . HOH CA 7 .   ? 3.48339  50.62385  -10.95094 1.000 44.88880 ? 1106 HOH B O   1 
HETATM 8536 O  O   . HOH CA 7 .   ? 32.02415 48.36744  -21.58720 1.000 29.27000 ? 1107 HOH B O   1 
HETATM 8537 O  O   . HOH CA 7 .   ? 11.03380 45.43960  -24.94464 1.000 41.79398 ? 1108 HOH B O   1 
HETATM 8538 O  O   . HOH CA 7 .   ? -8.616   32.597    -4.722    1.000 49.87527 ? 1109 HOH B O   1 
HETATM 8539 O  O   . HOH CA 7 .   ? 13.26975 53.37870  -21.04521 1.000 49.28445 ? 1110 HOH B O   1 
HETATM 8540 O  O   . HOH CA 7 .   ? 29.25469 51.02258  10.77983  1.000 47.72211 ? 1111 HOH B O   1 
HETATM 8541 O  O   . HOH CA 7 .   ? 32.86913 52.39708  -19.45822 1.000 34.38346 ? 1112 HOH B O   1 
HETATM 8542 O  O   . HOH CA 7 .   ? 7.99356  10.14665  -1.62494  1.000 38.66272 ? 1113 HOH B O   1 
HETATM 8543 O  O   . HOH CA 7 .   ? 39.12183 30.00081  -11.37285 1.000 35.85194 ? 1114 HOH B O   1 
HETATM 8544 O  O   . HOH CA 7 .   ? -1.32848 19.07407  -14.73071 1.000 37.61381 ? 1115 HOH B O   1 
HETATM 8545 O  O   . HOH CA 7 .   ? 23.14632 40.13810  14.21259  1.000 51.22506 ? 1116 HOH B O   1 
HETATM 8546 O  O   . HOH CA 7 .   ? 47.208   36.777    -0.334    1.000 49.02630 ? 1117 HOH B O   1 
HETATM 8547 O  O   . HOH CA 7 .   ? 30.56228 16.62457  -16.66744 1.000 25.23031 ? 1118 HOH B O   1 
HETATM 8548 O  O   . HOH CA 7 .   ? 16.46570 61.25298  -10.63692 1.000 40.73172 ? 1119 HOH B O   1 
HETATM 8549 O  O   . HOH CA 7 .   ? 29.79653 23.28049  -23.38247 1.000 28.82443 ? 1120 HOH B O   1 
HETATM 8550 O  O   A HOH CA 7 .   ? 26.28854 14.78158  -11.72010 0.630 25.03295 ? 1121 HOH B O   1 
HETATM 8551 O  O   B HOH CA 7 .   ? 27.07821 16.07459  -12.16538 0.370 24.35720 ? 1121 HOH B O   1 
HETATM 8552 O  O   . HOH CA 7 .   ? 19.34394 64.85263  -5.36164  1.000 48.02277 ? 1122 HOH B O   1 
HETATM 8553 O  O   . HOH CA 7 .   ? 2.00108  45.51720  -3.83307  1.000 46.68229 ? 1123 HOH B O   1 
HETATM 8554 O  O   . HOH CA 7 .   ? -2.99756 12.33956  -21.76313 1.000 45.38056 ? 1124 HOH B O   1 
HETATM 8555 O  O   . HOH CA 7 .   ? 33.01157 43.62595  4.90552   1.000 27.60786 ? 1125 HOH B O   1 
HETATM 8556 O  O   . HOH CA 7 .   ? 36.28469 53.87860  -5.75860  1.000 45.84454 ? 1126 HOH B O   1 
HETATM 8557 O  O   . HOH CA 7 .   ? 31.166   47.727    -39.228   1.000 47.30031 ? 1127 HOH B O   1 
HETATM 8558 O  O   . HOH CA 7 .   ? 43.43993 31.15320  -10.09192 1.000 50.28924 ? 1128 HOH B O   1 
HETATM 8559 O  O   . HOH CA 7 .   ? -0.57611 20.60992  -16.37931 1.000 37.72589 ? 1129 HOH B O   1 
HETATM 8560 O  O   . HOH CA 7 .   ? 26.58563 25.72120  -22.19446 1.000 19.37531 ? 1130 HOH B O   1 
HETATM 8561 O  O   . HOH CA 7 .   ? 30.935   57.946    -6.887    1.000 47.28379 ? 1131 HOH B O   1 
HETATM 8562 O  O   . HOH CA 7 .   ? 27.76798 56.32869  -20.35227 1.000 46.85553 ? 1132 HOH B O   1 
HETATM 8563 O  O   . HOH CA 7 .   ? 33.81965 25.16176  -12.85428 1.000 32.94017 ? 1133 HOH B O   1 
HETATM 8564 O  O   . HOH CA 7 .   ? -1.30439 22.78647  -22.95183 1.000 48.14645 ? 1134 HOH B O   1 
HETATM 8565 O  O   . HOH CA 7 .   ? 16.38669 58.48659  1.43830   1.000 39.61147 ? 1135 HOH B O   1 
HETATM 8566 O  O   . HOH CA 7 .   ? 35.96646 41.85953  -18.69203 1.000 31.15736 ? 1136 HOH B O   1 
HETATM 8567 O  O   . HOH CA 7 .   ? 22.04071 28.40051  -37.07845 1.000 44.61161 ? 1137 HOH B O   1 
HETATM 8568 O  O   . HOH CA 7 .   ? 3.02906  11.99415  -25.32759 1.000 47.63852 ? 1138 HOH B O   1 
HETATM 8569 O  O   . HOH CA 7 .   ? 3.62319  46.81570  -4.64821  1.000 39.50602 ? 1139 HOH B O   1 
HETATM 8570 O  O   . HOH CA 7 .   ? 5.46943  6.20309   -29.39206 1.000 39.19048 ? 1140 HOH B O   1 
HETATM 8571 O  O   . HOH CA 7 .   ? 29.12201 44.28703  11.77142  1.000 44.18505 ? 1141 HOH B O   1 
HETATM 8572 O  O   . HOH CA 7 .   ? 31.573   55.295    2.627     1.000 34.31595 ? 1142 HOH B O   1 
HETATM 8573 O  O   . HOH CA 7 .   ? 17.29134 50.21822  -27.89410 1.000 45.91646 ? 1143 HOH B O   1 
HETATM 8574 O  O   . HOH CA 7 .   ? 35.54356 48.80839  -24.46094 1.000 44.59862 ? 1144 HOH B O   1 
HETATM 8575 O  O   . HOH CA 7 .   ? 15.73606 24.26466  6.21999   1.000 43.95829 ? 1145 HOH B O   1 
HETATM 8576 O  O   . HOH CA 7 .   ? 36.69789 46.32333  -20.38928 1.000 37.71744 ? 1146 HOH B O   1 
HETATM 8577 O  O   . HOH CA 7 .   ? 14.03174 58.45524  0.46040   1.000 44.86561 ? 1147 HOH B O   1 
HETATM 8578 O  O   . HOH CA 7 .   ? 37.32191 41.40395  9.34249   1.000 52.37921 ? 1148 HOH B O   1 
HETATM 8579 O  O   . HOH CA 7 .   ? 18.87880 12.98104  -30.03220 1.000 49.72792 ? 1149 HOH B O   1 
HETATM 8580 O  O   A HOH CA 7 .   ? 3.00117  24.55777  -0.11564  0.349 26.52811 ? 1150 HOH B O   1 
HETATM 8581 O  O   B HOH CA 7 .   ? 4.14330  24.61061  -1.51895  0.651 23.60903 ? 1150 HOH B O   1 
HETATM 8582 O  O   . HOH CA 7 .   ? 23.33759 14.00240  -9.29612  1.000 24.43361 ? 1151 HOH B O   1 
HETATM 8583 O  O   . HOH CA 7 .   ? 32.45584 37.97536  -31.61040 1.000 36.41609 ? 1152 HOH B O   1 
HETATM 8584 O  O   . HOH CA 7 .   ? 34.22554 33.29858  -18.08631 1.000 27.63506 ? 1153 HOH B O   1 
HETATM 8585 O  O   . HOH CA 7 .   ? 31.68917 51.73960  7.06370   1.000 46.02811 ? 1154 HOH B O   1 
HETATM 8586 O  O   . HOH CA 7 .   ? 25.50694 31.41136  13.16143  1.000 31.77660 ? 1155 HOH B O   1 
HETATM 8587 O  O   . HOH CA 7 .   ? -7.179   39.794    1.817     1.000 40.56792 ? 1156 HOH B O   1 
HETATM 8588 O  O   . HOH CA 7 .   ? 30.32205 24.80383  14.63401  1.000 53.41824 ? 1157 HOH B O   1 
HETATM 8589 O  O   . HOH CA 7 .   ? 15.79065 22.85282  2.78719   1.000 32.91673 ? 1158 HOH B O   1 
HETATM 8590 O  O   . HOH CA 7 .   ? -1.11513 15.01726  -24.31494 1.000 52.83646 ? 1159 HOH B O   1 
HETATM 8591 O  O   . HOH CA 7 .   ? -3.49623 33.38807  -9.41650  1.000 48.41506 ? 1160 HOH B O   1 
HETATM 8592 O  O   . HOH CA 7 .   ? 33.60348 27.31527  -35.65540 1.000 42.62020 ? 1161 HOH B O   1 
HETATM 8593 O  O   . HOH CA 7 .   ? 37.38441 23.92391  -13.37314 1.000 45.65624 ? 1162 HOH B O   1 
HETATM 8594 O  O   . HOH CA 7 .   ? 30.39108 33.34798  13.57905  1.000 41.61248 ? 1163 HOH B O   1 
HETATM 8595 O  O   . HOH CA 7 .   ? -0.61284 23.85476  -3.07498  1.000 45.53173 ? 1164 HOH B O   1 
HETATM 8596 O  O   . HOH CA 7 .   ? 12.78622 27.87834  11.89107  1.000 51.70309 ? 1165 HOH B O   1 
HETATM 8597 O  O   . HOH CA 7 .   ? 42.17459 22.60717  4.58163   1.000 40.83275 ? 1166 HOH B O   1 
HETATM 8598 O  O   . HOH CA 7 .   ? 5.87847  31.63051  -19.16419 1.000 42.06435 ? 1167 HOH B O   1 
HETATM 8599 O  O   . HOH CA 7 .   ? 28.98368 54.06885  -20.29492 1.000 35.08346 ? 1168 HOH B O   1 
HETATM 8600 O  O   . HOH CA 7 .   ? 23.50720 39.60177  -32.82059 1.000 37.95586 ? 1169 HOH B O   1 
HETATM 8601 O  O   . HOH CA 7 .   ? 4.98244  14.50177  -29.21883 1.000 52.02985 ? 1170 HOH B O   1 
HETATM 8602 O  O   . HOH CA 7 .   ? 15.36383 50.76990  -26.31938 1.000 47.21212 ? 1171 HOH B O   1 
HETATM 8603 O  O   . HOH CA 7 .   ? -2.58915 25.41680  -1.27665  1.000 41.01534 ? 1172 HOH B O   1 
HETATM 8604 O  O   . HOH CA 7 .   ? 20.33664 13.87090  -0.75073  1.000 42.06179 ? 1173 HOH B O   1 
HETATM 8605 O  O   . HOH CA 7 .   ? 16.57978 26.69054  10.25606  1.000 48.46580 ? 1174 HOH B O   1 
HETATM 8606 O  O   . HOH CA 7 .   ? 3.31081  43.14215  -18.56934 1.000 51.61329 ? 1175 HOH B O   1 
HETATM 8607 O  O   . HOH CA 7 .   ? 21.77288 27.60368  12.23597  1.000 46.34796 ? 1176 HOH B O   1 
HETATM 8608 O  O   . HOH CA 7 .   ? 15.04804 4.14163   -17.21925 1.000 34.31522 ? 1177 HOH B O   1 
HETATM 8609 O  O   . HOH CA 7 .   ? 6.68042  22.86444  0.47326   1.000 33.58638 ? 1178 HOH B O   1 
HETATM 8610 O  O   . HOH CA 7 .   ? 22.67503 63.56942  4.69699   1.000 40.49420 ? 1179 HOH B O   1 
HETATM 8611 O  O   . HOH CA 7 .   ? 18.80891 51.53751  -26.76140 1.000 46.47290 ? 1180 HOH B O   1 
HETATM 8612 O  O   . HOH CA 7 .   ? 43.353   24.393    0.714     1.000 42.65912 ? 1181 HOH B O   1 
HETATM 8613 O  O   . HOH CA 7 .   ? 15.34839 30.59448  10.32591  1.000 33.68099 ? 1182 HOH B O   1 
HETATM 8614 O  O   . HOH CA 7 .   ? 32.98625 42.55671  10.01025  1.000 42.03943 ? 1183 HOH B O   1 
HETATM 8615 O  O   . HOH CA 7 .   ? 18.29543 20.99280  5.26201   1.000 31.10943 ? 1184 HOH B O   1 
HETATM 8616 O  O   . HOH CA 7 .   ? 49.10711 34.22912  -7.74208  1.000 49.21128 ? 1185 HOH B O   1 
HETATM 8617 O  O   . HOH CA 7 .   ? 34.14720 48.43397  4.53246   1.000 32.35074 ? 1186 HOH B O   1 
HETATM 8618 O  O   . HOH CA 7 .   ? 11.74056 -8.30562  -24.65685 1.000 29.87176 ? 1187 HOH B O   1 
HETATM 8619 O  O   . HOH CA 7 .   ? 18.43632 35.99465  -33.65654 1.000 45.15487 ? 1188 HOH B O   1 
HETATM 8620 O  O   . HOH CA 7 .   ? 6.53345  10.70693  -4.00540  1.000 30.27958 ? 1189 HOH B O   1 
HETATM 8621 O  O   . HOH CA 7 .   ? 39.45164 27.75891  -10.36647 1.000 36.89503 ? 1190 HOH B O   1 
HETATM 8622 O  O   . HOH CA 7 .   ? 5.93689  1.57681   -30.07675 1.000 44.76084 ? 1191 HOH B O   1 
HETATM 8623 O  O   . HOH CA 7 .   ? 30.30058 54.29392  -23.92243 1.000 42.31073 ? 1192 HOH B O   1 
HETATM 8624 O  O   . HOH CA 7 .   ? 20.16390 41.95404  -30.55172 1.000 46.30166 ? 1193 HOH B O   1 
HETATM 8625 O  O   . HOH CA 7 .   ? -5.388   31.598    1.471     1.000 38.59812 ? 1194 HOH B O   1 
HETATM 8626 O  O   . HOH CA 7 .   ? 24.94000 62.62574  4.30703   1.000 37.65607 ? 1195 HOH B O   1 
HETATM 8627 O  O   . HOH CA 7 .   ? 32.01950 51.21500  -21.86658 1.000 34.59413 ? 1196 HOH B O   1 
HETATM 8628 O  O   . HOH CA 7 .   ? 37.20575 47.73124  6.66668   1.000 52.31015 ? 1197 HOH B O   1 
HETATM 8629 O  O   . HOH CA 7 .   ? 10.21592 45.98486  13.33273  1.000 48.48200 ? 1198 HOH B O   1 
HETATM 8630 O  O   A HOH CA 7 .   ? 32.82207 18.49012  4.32884   0.419 26.63400 ? 1199 HOH B O   1 
HETATM 8631 O  O   B HOH CA 7 .   ? 33.77896 18.72679  5.47424   0.581 25.81967 ? 1199 HOH B O   1 
HETATM 8632 O  O   . HOH CA 7 .   ? 46.54624 46.27574  -12.58886 1.000 37.00333 ? 1200 HOH B O   1 
HETATM 8633 O  O   . HOH CA 7 .   ? 6.03611  7.28620   -18.86420 1.000 33.18268 ? 1201 HOH B O   1 
HETATM 8634 O  O   . HOH CA 7 .   ? 12.74521 31.90413  10.47382  1.000 28.11240 ? 1202 HOH B O   1 
HETATM 8635 O  O   . HOH CA 7 .   ? 24.24838 15.15828  -4.51900  1.000 33.77000 ? 1203 HOH B O   1 
HETATM 8636 O  O   . HOH CA 7 .   ? 34.41980 54.00770  0.82891   1.000 32.93356 ? 1204 HOH B O   1 
HETATM 8637 O  O   . HOH CA 7 .   ? 3.34326  43.12490  -13.25579 1.000 45.95585 ? 1205 HOH B O   1 
HETATM 8638 O  O   A HOH CA 7 .   ? 5.62097  40.25067  14.38658  0.376 33.49957 ? 1206 HOH B O   1 
HETATM 8639 O  O   B HOH CA 7 .   ? 6.78208  40.89040  13.27712  0.624 30.15025 ? 1206 HOH B O   1 
HETATM 8640 O  O   . HOH CA 7 .   ? 16.20346 19.11550  5.04750   1.000 45.44671 ? 1207 HOH B O   1 
HETATM 8641 O  O   . HOH CA 7 .   ? 33.09060 51.12345  4.70672   1.000 37.88351 ? 1208 HOH B O   1 
HETATM 8642 O  O   . HOH CA 7 .   ? 12.85332 2.80948   -18.59789 1.000 37.85249 ? 1209 HOH B O   1 
HETATM 8643 O  O   . HOH CA 7 .   ? -4.582   7.728     -3.179    1.000 38.82980 ? 1210 HOH B O   1 
HETATM 8644 O  O   . HOH CA 7 .   ? 14.78890 27.72478  -32.59539 1.000 39.40164 ? 1211 HOH B O   1 
HETATM 8645 O  O   . HOH CA 7 .   ? -0.35753 26.35779  -22.40647 1.000 45.05390 ? 1212 HOH B O   1 
HETATM 8646 O  O   . HOH CA 7 .   ? 15.13391 14.21488  1.81760   1.000 48.96643 ? 1213 HOH B O   1 
HETATM 8647 O  O   . HOH CA 7 .   ? 17.50858 27.27519  -35.07347 1.000 41.36912 ? 1214 HOH B O   1 
HETATM 8648 O  O   . HOH CA 7 .   ? 57.42479 40.08928  -14.66115 1.000 50.46652 ? 1215 HOH B O   1 
HETATM 8649 O  O   . HOH CA 7 .   ? 27.68844 32.30509  14.26677  1.000 35.02219 ? 1216 HOH B O   1 
HETATM 8650 O  O   . HOH CA 7 .   ? 32.31370 32.32043  14.52319  1.000 46.74752 ? 1217 HOH B O   1 
HETATM 8651 O  O   . HOH CA 7 .   ? 23.00772 59.88688  7.36789   1.000 50.07220 ? 1218 HOH B O   1 
HETATM 8652 O  O   . HOH CA 7 .   ? 21.09843 50.03712  -31.18762 1.000 56.22233 ? 1219 HOH B O   1 
HETATM 8653 O  O   . HOH CA 7 .   ? 14.06836 16.53886  3.53511   1.000 51.69592 ? 1220 HOH B O   1 
HETATM 8654 O  O   . HOH CA 7 .   ? 17.75043 40.61252  -30.49157 1.000 46.75006 ? 1221 HOH B O   1 
HETATM 8655 O  O   . HOH CA 7 .   ? 20.91525 12.78820  -4.92228  1.000 38.32422 ? 1222 HOH B O   1 
HETATM 8656 O  O   . HOH CA 7 .   ? 33.94071 52.13852  -23.39595 1.000 42.25135 ? 1223 HOH B O   1 
HETATM 8657 O  O   . HOH CA 7 .   ? 27.02547 34.19958  16.06035  1.000 48.21299 ? 1224 HOH B O   1 
HETATM 8658 O  O   . HOH CA 7 .   ? 15.85876 2.67398   -14.97765 1.000 38.24366 ? 1225 HOH B O   1 
HETATM 8659 O  O   . HOH CA 7 .   ? -1.91120 26.65430  -20.50962 1.000 53.91854 ? 1226 HOH B O   1 
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