data_9HBV
# 
_entry.id   9HBV 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9HBV         pdb_00009hbv 10.2210/pdb9hbv/pdb 
WWPDB D_1292142695 ?            ?                   
EMDB  EMD-52031    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-12 ? 
2 'EM metadata'     1 0 2025-03-12 ? 
3 'Additional map'  1 0 2025-03-12 1 
4 FSC               1 0 2025-03-12 ? 
5 'Half map'        1 0 2025-03-12 1 
6 'Half map'        1 0 2025-03-12 2 
7 Image             1 0 2025-03-12 ? 
8 Mask              1 0 2025-03-12 1 
9 'Primary map'     1 0 2025-03-12 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Additional map'  repository 'Initial release' ? ? 
4 4 FSC               repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 'Half map'        repository 'Initial release' ? ? 
7 7 Image             repository 'Initial release' ? ? 
8 8 Mask              repository 'Initial release' ? ? 
9 9 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9HBV 
_pdbx_database_status.recvd_initial_deposition_date   2024-11-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'TiLV-NP tetramer (pseudo-C4) (local refinement around 2 TiLV-NPs)' 
_pdbx_database_related.db_id          EMD-52031 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              cusack@embl.fr 
_pdbx_contact_author.name_first         Stephen 
_pdbx_contact_author.name_last          Cusack 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-9324-0796 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Arragain, B.' 1 0000-0002-5593-4682 
'Cusack, S.'   2 0000-0002-9324-0796 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nucleic Acids Res.' 
_citation.journal_id_ASTM           NARHAD 
_citation.journal_id_CSD            0389 
_citation.journal_id_ISSN           1362-4962 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            53 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structure of the tilapia lake virus nucleoprotein bound to RNA.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1093/nar/gkaf112 
_citation.pdbx_database_id_PubMed   39995042 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Arragain, B.' 1 ?                   
primary 'Pelosse, M.'  2 0000-0003-0840-7342 
primary 'Huard, K.'    3 ?                   
primary 'Cusack, S.'   4 0000-0002-9324-0796 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Tilapia Lake Virus nucleoprotein (segment 4)' 38387.129 3 ? ? ? ? 
2 polymer syn '40-mer vRNA loop'                             2982.934  1 ? ? ? 
;The RNA sequence (40-mer vRNA loop) is 5' - pGCA AAU CUU UCU CAC GUC CUG ACU UGU GAG UAA AAU UUG G - 3'. Due to the inability to precisely define bases, the exact nucleotide register remains elusive. Thus, in the modelling, generic purines (P5P) and generic pyrimidines (Y5P) were assigned based on apparent base size.
;
3 polymer syn '40-mer vRNA loop'                             5858.790  1 ? ? ? 
;The RNA sequence (40-mer vRNA loop) is 5' - pGCA AAU CUU UCU CAC GUC CUG ACU UGU GAG UAA AAU UUG G - 3'. Due to the inability to precisely define bases, the exact nucleotide register remains elusive. Thus, in the modelling, generic purines (P5P) and generic pyrimidines (Y5P) were assigned based on apparent base size.
;
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'   no no  
;MVRTTKTSMAAASTVAPEVAMDEGSPSTSQAQVELPRNLEVFNEACGHVFGSSFNREDNSVISDAAAFLFKMHTHSLDGQ
EAKVLRASEKKRERENAKKSRKAPEAGMRVGRSLILTSRWTEYCATCVPALGSKMKVIKASGDAAMIQMMKDHNSLLRVC
VRIEVWKARYVSLVALDERIQTLEDAQWFPYLSGDSYRACPGLVGGYFAKKAAAGERGKNYKKLNQTAIIPPPRFLIIGH
RLQIGDQVTLRELLASIAWGLCDGVLAECWSPSQGDGSIGVVVGLPLQATGSCFLVVASHGLSAIADSRIEGTGNTNLLE
ECIAIQKQDGVIKCKRSGKSLYHCLKETAGAVGR
;
;MVRTTKTSMAAASTVAPEVAMDEGSPSTSQAQVELPRNLEVFNEACGHVFGSSFNREDNSVISDAAAFLFKMHTHSLDGQ
EAKVLRASEKKRERENAKKSRKAPEAGMRVGRSLILTSRWTEYCATCVPALGSKMKVIKASGDAAMIQMMKDHNSLLRVC
VRIEVWKARYVSLVALDERIQTLEDAQWFPYLSGDSYRACPGLVGGYFAKKAAAGERGKNYKKLNQTAIIPPPRFLIIGH
RLQIGDQVTLRELLASIAWGLCDGVLAECWSPSQGDGSIGVVVGLPLQATGSCFLVVASHGLSAIADSRIEGTGNTNLLE
ECIAIQKQDGVIKCKRSGKSLYHCLKETAGAVGR
;
C,D,E ? 
2 polyribonucleotide no yes '(P5P)(P5P)(P5P)(P5P)(P5P)(Y5P)(Y5P)(P5P)(P5P)(Y5P)' AAAAAXXAAX O     ? 
3 polyribonucleotide no yes 
;(Y5P)(Y5P)(Y5P)(Y5P)(Y5P)(P5P)(Y5P)(P5P)(P5P)(P5P)(P5P)(P5P)(P5P)(P5P)(P5P)(Y5P)
(Y5P)(Y5P)(P5P)(Y5P)
;
XXXXXAXAAAAAAAAXXXAX N     ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   VAL n 
1 3   ARG n 
1 4   THR n 
1 5   THR n 
1 6   LYS n 
1 7   THR n 
1 8   SER n 
1 9   MET n 
1 10  ALA n 
1 11  ALA n 
1 12  ALA n 
1 13  SER n 
1 14  THR n 
1 15  VAL n 
1 16  ALA n 
1 17  PRO n 
1 18  GLU n 
1 19  VAL n 
1 20  ALA n 
1 21  MET n 
1 22  ASP n 
1 23  GLU n 
1 24  GLY n 
1 25  SER n 
1 26  PRO n 
1 27  SER n 
1 28  THR n 
1 29  SER n 
1 30  GLN n 
1 31  ALA n 
1 32  GLN n 
1 33  VAL n 
1 34  GLU n 
1 35  LEU n 
1 36  PRO n 
1 37  ARG n 
1 38  ASN n 
1 39  LEU n 
1 40  GLU n 
1 41  VAL n 
1 42  PHE n 
1 43  ASN n 
1 44  GLU n 
1 45  ALA n 
1 46  CYS n 
1 47  GLY n 
1 48  HIS n 
1 49  VAL n 
1 50  PHE n 
1 51  GLY n 
1 52  SER n 
1 53  SER n 
1 54  PHE n 
1 55  ASN n 
1 56  ARG n 
1 57  GLU n 
1 58  ASP n 
1 59  ASN n 
1 60  SER n 
1 61  VAL n 
1 62  ILE n 
1 63  SER n 
1 64  ASP n 
1 65  ALA n 
1 66  ALA n 
1 67  ALA n 
1 68  PHE n 
1 69  LEU n 
1 70  PHE n 
1 71  LYS n 
1 72  MET n 
1 73  HIS n 
1 74  THR n 
1 75  HIS n 
1 76  SER n 
1 77  LEU n 
1 78  ASP n 
1 79  GLY n 
1 80  GLN n 
1 81  GLU n 
1 82  ALA n 
1 83  LYS n 
1 84  VAL n 
1 85  LEU n 
1 86  ARG n 
1 87  ALA n 
1 88  SER n 
1 89  GLU n 
1 90  LYS n 
1 91  LYS n 
1 92  ARG n 
1 93  GLU n 
1 94  ARG n 
1 95  GLU n 
1 96  ASN n 
1 97  ALA n 
1 98  LYS n 
1 99  LYS n 
1 100 SER n 
1 101 ARG n 
1 102 LYS n 
1 103 ALA n 
1 104 PRO n 
1 105 GLU n 
1 106 ALA n 
1 107 GLY n 
1 108 MET n 
1 109 ARG n 
1 110 VAL n 
1 111 GLY n 
1 112 ARG n 
1 113 SER n 
1 114 LEU n 
1 115 ILE n 
1 116 LEU n 
1 117 THR n 
1 118 SER n 
1 119 ARG n 
1 120 TRP n 
1 121 THR n 
1 122 GLU n 
1 123 TYR n 
1 124 CYS n 
1 125 ALA n 
1 126 THR n 
1 127 CYS n 
1 128 VAL n 
1 129 PRO n 
1 130 ALA n 
1 131 LEU n 
1 132 GLY n 
1 133 SER n 
1 134 LYS n 
1 135 MET n 
1 136 LYS n 
1 137 VAL n 
1 138 ILE n 
1 139 LYS n 
1 140 ALA n 
1 141 SER n 
1 142 GLY n 
1 143 ASP n 
1 144 ALA n 
1 145 ALA n 
1 146 MET n 
1 147 ILE n 
1 148 GLN n 
1 149 MET n 
1 150 MET n 
1 151 LYS n 
1 152 ASP n 
1 153 HIS n 
1 154 ASN n 
1 155 SER n 
1 156 LEU n 
1 157 LEU n 
1 158 ARG n 
1 159 VAL n 
1 160 CYS n 
1 161 VAL n 
1 162 ARG n 
1 163 ILE n 
1 164 GLU n 
1 165 VAL n 
1 166 TRP n 
1 167 LYS n 
1 168 ALA n 
1 169 ARG n 
1 170 TYR n 
1 171 VAL n 
1 172 SER n 
1 173 LEU n 
1 174 VAL n 
1 175 ALA n 
1 176 LEU n 
1 177 ASP n 
1 178 GLU n 
1 179 ARG n 
1 180 ILE n 
1 181 GLN n 
1 182 THR n 
1 183 LEU n 
1 184 GLU n 
1 185 ASP n 
1 186 ALA n 
1 187 GLN n 
1 188 TRP n 
1 189 PHE n 
1 190 PRO n 
1 191 TYR n 
1 192 LEU n 
1 193 SER n 
1 194 GLY n 
1 195 ASP n 
1 196 SER n 
1 197 TYR n 
1 198 ARG n 
1 199 ALA n 
1 200 CYS n 
1 201 PRO n 
1 202 GLY n 
1 203 LEU n 
1 204 VAL n 
1 205 GLY n 
1 206 GLY n 
1 207 TYR n 
1 208 PHE n 
1 209 ALA n 
1 210 LYS n 
1 211 LYS n 
1 212 ALA n 
1 213 ALA n 
1 214 ALA n 
1 215 GLY n 
1 216 GLU n 
1 217 ARG n 
1 218 GLY n 
1 219 LYS n 
1 220 ASN n 
1 221 TYR n 
1 222 LYS n 
1 223 LYS n 
1 224 LEU n 
1 225 ASN n 
1 226 GLN n 
1 227 THR n 
1 228 ALA n 
1 229 ILE n 
1 230 ILE n 
1 231 PRO n 
1 232 PRO n 
1 233 PRO n 
1 234 ARG n 
1 235 PHE n 
1 236 LEU n 
1 237 ILE n 
1 238 ILE n 
1 239 GLY n 
1 240 HIS n 
1 241 ARG n 
1 242 LEU n 
1 243 GLN n 
1 244 ILE n 
1 245 GLY n 
1 246 ASP n 
1 247 GLN n 
1 248 VAL n 
1 249 THR n 
1 250 LEU n 
1 251 ARG n 
1 252 GLU n 
1 253 LEU n 
1 254 LEU n 
1 255 ALA n 
1 256 SER n 
1 257 ILE n 
1 258 ALA n 
1 259 TRP n 
1 260 GLY n 
1 261 LEU n 
1 262 CYS n 
1 263 ASP n 
1 264 GLY n 
1 265 VAL n 
1 266 LEU n 
1 267 ALA n 
1 268 GLU n 
1 269 CYS n 
1 270 TRP n 
1 271 SER n 
1 272 PRO n 
1 273 SER n 
1 274 GLN n 
1 275 GLY n 
1 276 ASP n 
1 277 GLY n 
1 278 SER n 
1 279 ILE n 
1 280 GLY n 
1 281 VAL n 
1 282 VAL n 
1 283 VAL n 
1 284 GLY n 
1 285 LEU n 
1 286 PRO n 
1 287 LEU n 
1 288 GLN n 
1 289 ALA n 
1 290 THR n 
1 291 GLY n 
1 292 SER n 
1 293 CYS n 
1 294 PHE n 
1 295 LEU n 
1 296 VAL n 
1 297 VAL n 
1 298 ALA n 
1 299 SER n 
1 300 HIS n 
1 301 GLY n 
1 302 LEU n 
1 303 SER n 
1 304 ALA n 
1 305 ILE n 
1 306 ALA n 
1 307 ASP n 
1 308 SER n 
1 309 ARG n 
1 310 ILE n 
1 311 GLU n 
1 312 GLY n 
1 313 THR n 
1 314 GLY n 
1 315 ASN n 
1 316 THR n 
1 317 ASN n 
1 318 LEU n 
1 319 LEU n 
1 320 GLU n 
1 321 GLU n 
1 322 CYS n 
1 323 ILE n 
1 324 ALA n 
1 325 ILE n 
1 326 GLN n 
1 327 LYS n 
1 328 GLN n 
1 329 ASP n 
1 330 GLY n 
1 331 VAL n 
1 332 ILE n 
1 333 LYS n 
1 334 CYS n 
1 335 LYS n 
1 336 ARG n 
1 337 SER n 
1 338 GLY n 
1 339 LYS n 
1 340 SER n 
1 341 LEU n 
1 342 TYR n 
1 343 HIS n 
1 344 CYS n 
1 345 LEU n 
1 346 LYS n 
1 347 GLU n 
1 348 THR n 
1 349 ALA n 
1 350 GLY n 
1 351 ALA n 
1 352 VAL n 
1 353 GLY n 
1 354 ARG n 
2 1   P5P n 
2 2   P5P n 
2 3   P5P n 
2 4   P5P n 
2 5   P5P n 
2 6   Y5P n 
2 7   Y5P n 
2 8   P5P n 
2 9   P5P n 
2 10  Y5P n 
3 1   Y5P n 
3 2   Y5P n 
3 3   Y5P n 
3 4   Y5P n 
3 5   Y5P n 
3 6   P5P n 
3 7   Y5P n 
3 8   P5P n 
3 9   P5P n 
3 10  P5P n 
3 11  P5P n 
3 12  P5P n 
3 13  P5P n 
3 14  P5P n 
3 15  P5P n 
3 16  Y5P n 
3 17  Y5P n 
3 18  Y5P n 
3 19  P5P n 
3 20  Y5P n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   354 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Tilapia lake virus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1549864 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Trichoplusia ni' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     7111 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_pdbx_entity_src_syn.entity_id 
_pdbx_entity_src_syn.pdbx_src_id 
_pdbx_entity_src_syn.pdbx_alt_source_flag 
_pdbx_entity_src_syn.pdbx_beg_seq_num 
_pdbx_entity_src_syn.pdbx_end_seq_num 
_pdbx_entity_src_syn.organism_scientific 
_pdbx_entity_src_syn.organism_common_name 
_pdbx_entity_src_syn.ncbi_taxonomy_id 
_pdbx_entity_src_syn.details 
2 1 sample 1 10 'Tilapia lake virus' ? 1549864 ? 
3 1 sample 1 20 'Tilapia lake virus' ? 1549864 ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                                        ?                                      
'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                                                       ?                                      
'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                     ?                                      
'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                ?                                      
'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE                                                       ?                                      
'C3 H7 N O2 S'    121.158 
GLN 'L-peptide linking' y GLUTAMINE                                                      ?                                      
'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                ?                                      
'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                                                        ?                                      
'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                                                      ?                                      
'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE                                                     ?                                      
'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                                                        ?                                      
'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                                                         ?                                      
'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                                                     ?                                      
'C5 H11 N O2 S'   149.211 
P5P 'RNA linking'       n 
;PURINE RIBOSIDE-5'-MONOPHOSPHATE
;
?                                      'C10 H13 N4 O7 P' 332.207 
PHE 'L-peptide linking' y PHENYLALANINE                                                  ?                                      
'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                                                        ?                                      
'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                                                         ?                                      
'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                                                      ?                                      
'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                     ?                                      
'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                                                       ?                                      
'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                                                         ?                                      
'C5 H11 N O2'     117.146 
Y5P 'RNA linking'       . '1-(5-O-phosphono-beta-D-ribofuranosyl)-1,4-dihydropyrimidine' 
;PYRIMIDINE RIBOSIDE-5'-MONOPHOSPHATE
;
'C9 H15 N2 O7 P'  294.198 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   C . n 
A 1 2   VAL 2   2   ?   ?   ?   C . n 
A 1 3   ARG 3   3   ?   ?   ?   C . n 
A 1 4   THR 4   4   ?   ?   ?   C . n 
A 1 5   THR 5   5   ?   ?   ?   C . n 
A 1 6   LYS 6   6   ?   ?   ?   C . n 
A 1 7   THR 7   7   ?   ?   ?   C . n 
A 1 8   SER 8   8   ?   ?   ?   C . n 
A 1 9   MET 9   9   ?   ?   ?   C . n 
A 1 10  ALA 10  10  ?   ?   ?   C . n 
A 1 11  ALA 11  11  ?   ?   ?   C . n 
A 1 12  ALA 12  12  ?   ?   ?   C . n 
A 1 13  SER 13  13  ?   ?   ?   C . n 
A 1 14  THR 14  14  ?   ?   ?   C . n 
A 1 15  VAL 15  15  ?   ?   ?   C . n 
A 1 16  ALA 16  16  ?   ?   ?   C . n 
A 1 17  PRO 17  17  ?   ?   ?   C . n 
A 1 18  GLU 18  18  ?   ?   ?   C . n 
A 1 19  VAL 19  19  ?   ?   ?   C . n 
A 1 20  ALA 20  20  ?   ?   ?   C . n 
A 1 21  MET 21  21  ?   ?   ?   C . n 
A 1 22  ASP 22  22  ?   ?   ?   C . n 
A 1 23  GLU 23  23  ?   ?   ?   C . n 
A 1 24  GLY 24  24  ?   ?   ?   C . n 
A 1 25  SER 25  25  ?   ?   ?   C . n 
A 1 26  PRO 26  26  ?   ?   ?   C . n 
A 1 27  SER 27  27  ?   ?   ?   C . n 
A 1 28  THR 28  28  ?   ?   ?   C . n 
A 1 29  SER 29  29  ?   ?   ?   C . n 
A 1 30  GLN 30  30  ?   ?   ?   C . n 
A 1 31  ALA 31  31  ?   ?   ?   C . n 
A 1 32  GLN 32  32  ?   ?   ?   C . n 
A 1 33  VAL 33  33  ?   ?   ?   C . n 
A 1 34  GLU 34  34  34  GLU GLU C . n 
A 1 35  LEU 35  35  35  LEU LEU C . n 
A 1 36  PRO 36  36  36  PRO PRO C . n 
A 1 37  ARG 37  37  37  ARG ARG C . n 
A 1 38  ASN 38  38  38  ASN ASN C . n 
A 1 39  LEU 39  39  39  LEU LEU C . n 
A 1 40  GLU 40  40  40  GLU GLU C . n 
A 1 41  VAL 41  41  41  VAL VAL C . n 
A 1 42  PHE 42  42  42  PHE PHE C . n 
A 1 43  ASN 43  43  43  ASN ASN C . n 
A 1 44  GLU 44  44  44  GLU GLU C . n 
A 1 45  ALA 45  45  45  ALA ALA C . n 
A 1 46  CYS 46  46  46  CYS CYS C . n 
A 1 47  GLY 47  47  47  GLY GLY C . n 
A 1 48  HIS 48  48  48  HIS HIS C . n 
A 1 49  VAL 49  49  49  VAL VAL C . n 
A 1 50  PHE 50  50  50  PHE PHE C . n 
A 1 51  GLY 51  51  51  GLY GLY C . n 
A 1 52  SER 52  52  52  SER SER C . n 
A 1 53  SER 53  53  53  SER SER C . n 
A 1 54  PHE 54  54  54  PHE PHE C . n 
A 1 55  ASN 55  55  55  ASN ASN C . n 
A 1 56  ARG 56  56  56  ARG ARG C . n 
A 1 57  GLU 57  57  57  GLU GLU C . n 
A 1 58  ASP 58  58  58  ASP ASP C . n 
A 1 59  ASN 59  59  59  ASN ASN C . n 
A 1 60  SER 60  60  60  SER SER C . n 
A 1 61  VAL 61  61  61  VAL VAL C . n 
A 1 62  ILE 62  62  62  ILE ILE C . n 
A 1 63  SER 63  63  63  SER SER C . n 
A 1 64  ASP 64  64  64  ASP ASP C . n 
A 1 65  ALA 65  65  65  ALA ALA C . n 
A 1 66  ALA 66  66  66  ALA ALA C . n 
A 1 67  ALA 67  67  67  ALA ALA C . n 
A 1 68  PHE 68  68  68  PHE PHE C . n 
A 1 69  LEU 69  69  69  LEU LEU C . n 
A 1 70  PHE 70  70  70  PHE PHE C . n 
A 1 71  LYS 71  71  71  LYS LYS C . n 
A 1 72  MET 72  72  72  MET MET C . n 
A 1 73  HIS 73  73  73  HIS HIS C . n 
A 1 74  THR 74  74  74  THR THR C . n 
A 1 75  HIS 75  75  75  HIS HIS C . n 
A 1 76  SER 76  76  76  SER SER C . n 
A 1 77  LEU 77  77  77  LEU LEU C . n 
A 1 78  ASP 78  78  78  ASP ASP C . n 
A 1 79  GLY 79  79  79  GLY GLY C . n 
A 1 80  GLN 80  80  80  GLN GLN C . n 
A 1 81  GLU 81  81  81  GLU GLU C . n 
A 1 82  ALA 82  82  82  ALA ALA C . n 
A 1 83  LYS 83  83  83  LYS LYS C . n 
A 1 84  VAL 84  84  84  VAL VAL C . n 
A 1 85  LEU 85  85  85  LEU LEU C . n 
A 1 86  ARG 86  86  86  ARG ARG C . n 
A 1 87  ALA 87  87  87  ALA ALA C . n 
A 1 88  SER 88  88  88  SER SER C . n 
A 1 89  GLU 89  89  89  GLU GLU C . n 
A 1 90  LYS 90  90  90  LYS LYS C . n 
A 1 91  LYS 91  91  91  LYS LYS C . n 
A 1 92  ARG 92  92  92  ARG ARG C . n 
A 1 93  GLU 93  93  93  GLU GLU C . n 
A 1 94  ARG 94  94  94  ARG ARG C . n 
A 1 95  GLU 95  95  95  GLU GLU C . n 
A 1 96  ASN 96  96  96  ASN ASN C . n 
A 1 97  ALA 97  97  97  ALA ALA C . n 
A 1 98  LYS 98  98  98  LYS LYS C . n 
A 1 99  LYS 99  99  99  LYS LYS C . n 
A 1 100 SER 100 100 100 SER SER C . n 
A 1 101 ARG 101 101 101 ARG ARG C . n 
A 1 102 LYS 102 102 102 LYS LYS C . n 
A 1 103 ALA 103 103 103 ALA ALA C . n 
A 1 104 PRO 104 104 104 PRO PRO C . n 
A 1 105 GLU 105 105 105 GLU GLU C . n 
A 1 106 ALA 106 106 106 ALA ALA C . n 
A 1 107 GLY 107 107 107 GLY GLY C . n 
A 1 108 MET 108 108 108 MET MET C . n 
A 1 109 ARG 109 109 109 ARG ARG C . n 
A 1 110 VAL 110 110 110 VAL VAL C . n 
A 1 111 GLY 111 111 111 GLY GLY C . n 
A 1 112 ARG 112 112 112 ARG ARG C . n 
A 1 113 SER 113 113 113 SER SER C . n 
A 1 114 LEU 114 114 114 LEU LEU C . n 
A 1 115 ILE 115 115 115 ILE ILE C . n 
A 1 116 LEU 116 116 116 LEU LEU C . n 
A 1 117 THR 117 117 117 THR THR C . n 
A 1 118 SER 118 118 118 SER SER C . n 
A 1 119 ARG 119 119 119 ARG ARG C . n 
A 1 120 TRP 120 120 120 TRP TRP C . n 
A 1 121 THR 121 121 121 THR THR C . n 
A 1 122 GLU 122 122 122 GLU GLU C . n 
A 1 123 TYR 123 123 123 TYR TYR C . n 
A 1 124 CYS 124 124 124 CYS CYS C . n 
A 1 125 ALA 125 125 125 ALA ALA C . n 
A 1 126 THR 126 126 126 THR THR C . n 
A 1 127 CYS 127 127 127 CYS CYS C . n 
A 1 128 VAL 128 128 128 VAL VAL C . n 
A 1 129 PRO 129 129 129 PRO PRO C . n 
A 1 130 ALA 130 130 130 ALA ALA C . n 
A 1 131 LEU 131 131 131 LEU LEU C . n 
A 1 132 GLY 132 132 132 GLY GLY C . n 
A 1 133 SER 133 133 133 SER SER C . n 
A 1 134 LYS 134 134 134 LYS LYS C . n 
A 1 135 MET 135 135 135 MET MET C . n 
A 1 136 LYS 136 136 136 LYS LYS C . n 
A 1 137 VAL 137 137 137 VAL VAL C . n 
A 1 138 ILE 138 138 138 ILE ILE C . n 
A 1 139 LYS 139 139 139 LYS LYS C . n 
A 1 140 ALA 140 140 140 ALA ALA C . n 
A 1 141 SER 141 141 141 SER SER C . n 
A 1 142 GLY 142 142 142 GLY GLY C . n 
A 1 143 ASP 143 143 143 ASP ASP C . n 
A 1 144 ALA 144 144 144 ALA ALA C . n 
A 1 145 ALA 145 145 145 ALA ALA C . n 
A 1 146 MET 146 146 146 MET MET C . n 
A 1 147 ILE 147 147 147 ILE ILE C . n 
A 1 148 GLN 148 148 148 GLN GLN C . n 
A 1 149 MET 149 149 149 MET MET C . n 
A 1 150 MET 150 150 150 MET MET C . n 
A 1 151 LYS 151 151 151 LYS LYS C . n 
A 1 152 ASP 152 152 152 ASP ASP C . n 
A 1 153 HIS 153 153 153 HIS HIS C . n 
A 1 154 ASN 154 154 154 ASN ASN C . n 
A 1 155 SER 155 155 155 SER SER C . n 
A 1 156 LEU 156 156 156 LEU LEU C . n 
A 1 157 LEU 157 157 157 LEU LEU C . n 
A 1 158 ARG 158 158 158 ARG ARG C . n 
A 1 159 VAL 159 159 159 VAL VAL C . n 
A 1 160 CYS 160 160 160 CYS CYS C . n 
A 1 161 VAL 161 161 161 VAL VAL C . n 
A 1 162 ARG 162 162 162 ARG ARG C . n 
A 1 163 ILE 163 163 163 ILE ILE C . n 
A 1 164 GLU 164 164 164 GLU GLU C . n 
A 1 165 VAL 165 165 165 VAL VAL C . n 
A 1 166 TRP 166 166 166 TRP TRP C . n 
A 1 167 LYS 167 167 167 LYS LYS C . n 
A 1 168 ALA 168 168 168 ALA ALA C . n 
A 1 169 ARG 169 169 169 ARG ARG C . n 
A 1 170 TYR 170 170 170 TYR TYR C . n 
A 1 171 VAL 171 171 171 VAL VAL C . n 
A 1 172 SER 172 172 172 SER SER C . n 
A 1 173 LEU 173 173 173 LEU LEU C . n 
A 1 174 VAL 174 174 174 VAL VAL C . n 
A 1 175 ALA 175 175 175 ALA ALA C . n 
A 1 176 LEU 176 176 176 LEU LEU C . n 
A 1 177 ASP 177 177 177 ASP ASP C . n 
A 1 178 GLU 178 178 178 GLU GLU C . n 
A 1 179 ARG 179 179 179 ARG ARG C . n 
A 1 180 ILE 180 180 180 ILE ILE C . n 
A 1 181 GLN 181 181 181 GLN GLN C . n 
A 1 182 THR 182 182 182 THR THR C . n 
A 1 183 LEU 183 183 183 LEU LEU C . n 
A 1 184 GLU 184 184 184 GLU GLU C . n 
A 1 185 ASP 185 185 185 ASP ASP C . n 
A 1 186 ALA 186 186 186 ALA ALA C . n 
A 1 187 GLN 187 187 187 GLN GLN C . n 
A 1 188 TRP 188 188 188 TRP TRP C . n 
A 1 189 PHE 189 189 189 PHE PHE C . n 
A 1 190 PRO 190 190 190 PRO PRO C . n 
A 1 191 TYR 191 191 191 TYR TYR C . n 
A 1 192 LEU 192 192 192 LEU LEU C . n 
A 1 193 SER 193 193 193 SER SER C . n 
A 1 194 GLY 194 194 194 GLY GLY C . n 
A 1 195 ASP 195 195 195 ASP ASP C . n 
A 1 196 SER 196 196 196 SER SER C . n 
A 1 197 TYR 197 197 197 TYR TYR C . n 
A 1 198 ARG 198 198 198 ARG ARG C . n 
A 1 199 ALA 199 199 199 ALA ALA C . n 
A 1 200 CYS 200 200 200 CYS CYS C . n 
A 1 201 PRO 201 201 201 PRO PRO C . n 
A 1 202 GLY 202 202 202 GLY GLY C . n 
A 1 203 LEU 203 203 203 LEU LEU C . n 
A 1 204 VAL 204 204 204 VAL VAL C . n 
A 1 205 GLY 205 205 205 GLY GLY C . n 
A 1 206 GLY 206 206 206 GLY GLY C . n 
A 1 207 TYR 207 207 207 TYR TYR C . n 
A 1 208 PHE 208 208 208 PHE PHE C . n 
A 1 209 ALA 209 209 209 ALA ALA C . n 
A 1 210 LYS 210 210 210 LYS LYS C . n 
A 1 211 LYS 211 211 211 LYS LYS C . n 
A 1 212 ALA 212 212 212 ALA ALA C . n 
A 1 213 ALA 213 213 213 ALA ALA C . n 
A 1 214 ALA 214 214 214 ALA ALA C . n 
A 1 215 GLY 215 215 215 GLY GLY C . n 
A 1 216 GLU 216 216 216 GLU GLU C . n 
A 1 217 ARG 217 217 217 ARG ARG C . n 
A 1 218 GLY 218 218 218 GLY GLY C . n 
A 1 219 LYS 219 219 219 LYS LYS C . n 
A 1 220 ASN 220 220 220 ASN ASN C . n 
A 1 221 TYR 221 221 221 TYR TYR C . n 
A 1 222 LYS 222 222 222 LYS LYS C . n 
A 1 223 LYS 223 223 223 LYS LYS C . n 
A 1 224 LEU 224 224 224 LEU LEU C . n 
A 1 225 ASN 225 225 225 ASN ASN C . n 
A 1 226 GLN 226 226 226 GLN GLN C . n 
A 1 227 THR 227 227 227 THR THR C . n 
A 1 228 ALA 228 228 228 ALA ALA C . n 
A 1 229 ILE 229 229 229 ILE ILE C . n 
A 1 230 ILE 230 230 230 ILE ILE C . n 
A 1 231 PRO 231 231 231 PRO PRO C . n 
A 1 232 PRO 232 232 232 PRO PRO C . n 
A 1 233 PRO 233 233 233 PRO PRO C . n 
A 1 234 ARG 234 234 234 ARG ARG C . n 
A 1 235 PHE 235 235 235 PHE PHE C . n 
A 1 236 LEU 236 236 236 LEU LEU C . n 
A 1 237 ILE 237 237 237 ILE ILE C . n 
A 1 238 ILE 238 238 238 ILE ILE C . n 
A 1 239 GLY 239 239 239 GLY GLY C . n 
A 1 240 HIS 240 240 240 HIS HIS C . n 
A 1 241 ARG 241 241 241 ARG ARG C . n 
A 1 242 LEU 242 242 242 LEU LEU C . n 
A 1 243 GLN 243 243 243 GLN GLN C . n 
A 1 244 ILE 244 244 244 ILE ILE C . n 
A 1 245 GLY 245 245 245 GLY GLY C . n 
A 1 246 ASP 246 246 246 ASP ASP C . n 
A 1 247 GLN 247 247 247 GLN GLN C . n 
A 1 248 VAL 248 248 248 VAL VAL C . n 
A 1 249 THR 249 249 249 THR THR C . n 
A 1 250 LEU 250 250 250 LEU LEU C . n 
A 1 251 ARG 251 251 251 ARG ARG C . n 
A 1 252 GLU 252 252 252 GLU GLU C . n 
A 1 253 LEU 253 253 253 LEU LEU C . n 
A 1 254 LEU 254 254 254 LEU LEU C . n 
A 1 255 ALA 255 255 255 ALA ALA C . n 
A 1 256 SER 256 256 256 SER SER C . n 
A 1 257 ILE 257 257 257 ILE ILE C . n 
A 1 258 ALA 258 258 258 ALA ALA C . n 
A 1 259 TRP 259 259 259 TRP TRP C . n 
A 1 260 GLY 260 260 260 GLY GLY C . n 
A 1 261 LEU 261 261 261 LEU LEU C . n 
A 1 262 CYS 262 262 262 CYS CYS C . n 
A 1 263 ASP 263 263 263 ASP ASP C . n 
A 1 264 GLY 264 264 264 GLY GLY C . n 
A 1 265 VAL 265 265 265 VAL VAL C . n 
A 1 266 LEU 266 266 266 LEU LEU C . n 
A 1 267 ALA 267 267 267 ALA ALA C . n 
A 1 268 GLU 268 268 268 GLU GLU C . n 
A 1 269 CYS 269 269 269 CYS CYS C . n 
A 1 270 TRP 270 270 270 TRP TRP C . n 
A 1 271 SER 271 271 271 SER SER C . n 
A 1 272 PRO 272 272 272 PRO PRO C . n 
A 1 273 SER 273 273 273 SER SER C . n 
A 1 274 GLN 274 274 274 GLN GLN C . n 
A 1 275 GLY 275 275 275 GLY GLY C . n 
A 1 276 ASP 276 276 276 ASP ASP C . n 
A 1 277 GLY 277 277 277 GLY GLY C . n 
A 1 278 SER 278 278 278 SER SER C . n 
A 1 279 ILE 279 279 279 ILE ILE C . n 
A 1 280 GLY 280 280 280 GLY GLY C . n 
A 1 281 VAL 281 281 281 VAL VAL C . n 
A 1 282 VAL 282 282 282 VAL VAL C . n 
A 1 283 VAL 283 283 283 VAL VAL C . n 
A 1 284 GLY 284 284 284 GLY GLY C . n 
A 1 285 LEU 285 285 285 LEU LEU C . n 
A 1 286 PRO 286 286 286 PRO PRO C . n 
A 1 287 LEU 287 287 287 LEU LEU C . n 
A 1 288 GLN 288 288 288 GLN GLN C . n 
A 1 289 ALA 289 289 289 ALA ALA C . n 
A 1 290 THR 290 290 ?   ?   ?   C . n 
A 1 291 GLY 291 291 ?   ?   ?   C . n 
A 1 292 SER 292 292 ?   ?   ?   C . n 
A 1 293 CYS 293 293 ?   ?   ?   C . n 
A 1 294 PHE 294 294 ?   ?   ?   C . n 
A 1 295 LEU 295 295 ?   ?   ?   C . n 
A 1 296 VAL 296 296 ?   ?   ?   C . n 
A 1 297 VAL 297 297 ?   ?   ?   C . n 
A 1 298 ALA 298 298 ?   ?   ?   C . n 
A 1 299 SER 299 299 ?   ?   ?   C . n 
A 1 300 HIS 300 300 ?   ?   ?   C . n 
A 1 301 GLY 301 301 ?   ?   ?   C . n 
A 1 302 LEU 302 302 ?   ?   ?   C . n 
A 1 303 SER 303 303 ?   ?   ?   C . n 
A 1 304 ALA 304 304 ?   ?   ?   C . n 
A 1 305 ILE 305 305 ?   ?   ?   C . n 
A 1 306 ALA 306 306 ?   ?   ?   C . n 
A 1 307 ASP 307 307 ?   ?   ?   C . n 
A 1 308 SER 308 308 ?   ?   ?   C . n 
A 1 309 ARG 309 309 ?   ?   ?   C . n 
A 1 310 ILE 310 310 ?   ?   ?   C . n 
A 1 311 GLU 311 311 ?   ?   ?   C . n 
A 1 312 GLY 312 312 ?   ?   ?   C . n 
A 1 313 THR 313 313 ?   ?   ?   C . n 
A 1 314 GLY 314 314 ?   ?   ?   C . n 
A 1 315 ASN 315 315 ?   ?   ?   C . n 
A 1 316 THR 316 316 316 THR THR C . n 
A 1 317 ASN 317 317 317 ASN ASN C . n 
A 1 318 LEU 318 318 318 LEU LEU C . n 
A 1 319 LEU 319 319 319 LEU LEU C . n 
A 1 320 GLU 320 320 320 GLU GLU C . n 
A 1 321 GLU 321 321 321 GLU GLU C . n 
A 1 322 CYS 322 322 322 CYS CYS C . n 
A 1 323 ILE 323 323 323 ILE ILE C . n 
A 1 324 ALA 324 324 324 ALA ALA C . n 
A 1 325 ILE 325 325 325 ILE ILE C . n 
A 1 326 GLN 326 326 326 GLN GLN C . n 
A 1 327 LYS 327 327 327 LYS LYS C . n 
A 1 328 GLN 328 328 328 GLN GLN C . n 
A 1 329 ASP 329 329 329 ASP ASP C . n 
A 1 330 GLY 330 330 330 GLY GLY C . n 
A 1 331 VAL 331 331 331 VAL VAL C . n 
A 1 332 ILE 332 332 332 ILE ILE C . n 
A 1 333 LYS 333 333 333 LYS LYS C . n 
A 1 334 CYS 334 334 334 CYS CYS C . n 
A 1 335 LYS 335 335 335 LYS LYS C . n 
A 1 336 ARG 336 336 336 ARG ARG C . n 
A 1 337 SER 337 337 337 SER SER C . n 
A 1 338 GLY 338 338 338 GLY GLY C . n 
A 1 339 LYS 339 339 339 LYS LYS C . n 
A 1 340 SER 340 340 340 SER SER C . n 
A 1 341 LEU 341 341 341 LEU LEU C . n 
A 1 342 TYR 342 342 342 TYR TYR C . n 
A 1 343 HIS 343 343 343 HIS HIS C . n 
A 1 344 CYS 344 344 344 CYS CYS C . n 
A 1 345 LEU 345 345 345 LEU LEU C . n 
A 1 346 LYS 346 346 346 LYS LYS C . n 
A 1 347 GLU 347 347 347 GLU GLU C . n 
A 1 348 THR 348 348 348 THR THR C . n 
A 1 349 ALA 349 349 349 ALA ALA C . n 
A 1 350 GLY 350 350 350 GLY GLY C . n 
A 1 351 ALA 351 351 ?   ?   ?   C . n 
A 1 352 VAL 352 352 ?   ?   ?   C . n 
A 1 353 GLY 353 353 ?   ?   ?   C . n 
A 1 354 ARG 354 354 ?   ?   ?   C . n 
B 1 1   MET 1   1   ?   ?   ?   D . n 
B 1 2   VAL 2   2   ?   ?   ?   D . n 
B 1 3   ARG 3   3   ?   ?   ?   D . n 
B 1 4   THR 4   4   ?   ?   ?   D . n 
B 1 5   THR 5   5   ?   ?   ?   D . n 
B 1 6   LYS 6   6   ?   ?   ?   D . n 
B 1 7   THR 7   7   ?   ?   ?   D . n 
B 1 8   SER 8   8   ?   ?   ?   D . n 
B 1 9   MET 9   9   ?   ?   ?   D . n 
B 1 10  ALA 10  10  ?   ?   ?   D . n 
B 1 11  ALA 11  11  ?   ?   ?   D . n 
B 1 12  ALA 12  12  ?   ?   ?   D . n 
B 1 13  SER 13  13  ?   ?   ?   D . n 
B 1 14  THR 14  14  ?   ?   ?   D . n 
B 1 15  VAL 15  15  ?   ?   ?   D . n 
B 1 16  ALA 16  16  ?   ?   ?   D . n 
B 1 17  PRO 17  17  ?   ?   ?   D . n 
B 1 18  GLU 18  18  ?   ?   ?   D . n 
B 1 19  VAL 19  19  ?   ?   ?   D . n 
B 1 20  ALA 20  20  ?   ?   ?   D . n 
B 1 21  MET 21  21  ?   ?   ?   D . n 
B 1 22  ASP 22  22  ?   ?   ?   D . n 
B 1 23  GLU 23  23  ?   ?   ?   D . n 
B 1 24  GLY 24  24  ?   ?   ?   D . n 
B 1 25  SER 25  25  ?   ?   ?   D . n 
B 1 26  PRO 26  26  ?   ?   ?   D . n 
B 1 27  SER 27  27  ?   ?   ?   D . n 
B 1 28  THR 28  28  ?   ?   ?   D . n 
B 1 29  SER 29  29  ?   ?   ?   D . n 
B 1 30  GLN 30  30  ?   ?   ?   D . n 
B 1 31  ALA 31  31  ?   ?   ?   D . n 
B 1 32  GLN 32  32  ?   ?   ?   D . n 
B 1 33  VAL 33  33  ?   ?   ?   D . n 
B 1 34  GLU 34  34  34  GLU GLU D . n 
B 1 35  LEU 35  35  35  LEU LEU D . n 
B 1 36  PRO 36  36  36  PRO PRO D . n 
B 1 37  ARG 37  37  37  ARG ARG D . n 
B 1 38  ASN 38  38  38  ASN ASN D . n 
B 1 39  LEU 39  39  39  LEU LEU D . n 
B 1 40  GLU 40  40  40  GLU GLU D . n 
B 1 41  VAL 41  41  41  VAL VAL D . n 
B 1 42  PHE 42  42  42  PHE PHE D . n 
B 1 43  ASN 43  43  43  ASN ASN D . n 
B 1 44  GLU 44  44  44  GLU GLU D . n 
B 1 45  ALA 45  45  45  ALA ALA D . n 
B 1 46  CYS 46  46  46  CYS CYS D . n 
B 1 47  GLY 47  47  47  GLY GLY D . n 
B 1 48  HIS 48  48  48  HIS HIS D . n 
B 1 49  VAL 49  49  49  VAL VAL D . n 
B 1 50  PHE 50  50  50  PHE PHE D . n 
B 1 51  GLY 51  51  51  GLY GLY D . n 
B 1 52  SER 52  52  52  SER SER D . n 
B 1 53  SER 53  53  53  SER SER D . n 
B 1 54  PHE 54  54  54  PHE PHE D . n 
B 1 55  ASN 55  55  55  ASN ASN D . n 
B 1 56  ARG 56  56  56  ARG ARG D . n 
B 1 57  GLU 57  57  57  GLU GLU D . n 
B 1 58  ASP 58  58  58  ASP ASP D . n 
B 1 59  ASN 59  59  59  ASN ASN D . n 
B 1 60  SER 60  60  60  SER SER D . n 
B 1 61  VAL 61  61  61  VAL VAL D . n 
B 1 62  ILE 62  62  62  ILE ILE D . n 
B 1 63  SER 63  63  63  SER SER D . n 
B 1 64  ASP 64  64  64  ASP ASP D . n 
B 1 65  ALA 65  65  65  ALA ALA D . n 
B 1 66  ALA 66  66  66  ALA ALA D . n 
B 1 67  ALA 67  67  67  ALA ALA D . n 
B 1 68  PHE 68  68  68  PHE PHE D . n 
B 1 69  LEU 69  69  69  LEU LEU D . n 
B 1 70  PHE 70  70  70  PHE PHE D . n 
B 1 71  LYS 71  71  71  LYS LYS D . n 
B 1 72  MET 72  72  72  MET MET D . n 
B 1 73  HIS 73  73  73  HIS HIS D . n 
B 1 74  THR 74  74  74  THR THR D . n 
B 1 75  HIS 75  75  75  HIS HIS D . n 
B 1 76  SER 76  76  76  SER SER D . n 
B 1 77  LEU 77  77  77  LEU LEU D . n 
B 1 78  ASP 78  78  78  ASP ASP D . n 
B 1 79  GLY 79  79  79  GLY GLY D . n 
B 1 80  GLN 80  80  80  GLN GLN D . n 
B 1 81  GLU 81  81  81  GLU GLU D . n 
B 1 82  ALA 82  82  82  ALA ALA D . n 
B 1 83  LYS 83  83  83  LYS LYS D . n 
B 1 84  VAL 84  84  84  VAL VAL D . n 
B 1 85  LEU 85  85  85  LEU LEU D . n 
B 1 86  ARG 86  86  86  ARG ARG D . n 
B 1 87  ALA 87  87  87  ALA ALA D . n 
B 1 88  SER 88  88  88  SER SER D . n 
B 1 89  GLU 89  89  89  GLU GLU D . n 
B 1 90  LYS 90  90  90  LYS LYS D . n 
B 1 91  LYS 91  91  91  LYS LYS D . n 
B 1 92  ARG 92  92  92  ARG ARG D . n 
B 1 93  GLU 93  93  93  GLU GLU D . n 
B 1 94  ARG 94  94  94  ARG ARG D . n 
B 1 95  GLU 95  95  95  GLU GLU D . n 
B 1 96  ASN 96  96  96  ASN ASN D . n 
B 1 97  ALA 97  97  97  ALA ALA D . n 
B 1 98  LYS 98  98  98  LYS LYS D . n 
B 1 99  LYS 99  99  99  LYS LYS D . n 
B 1 100 SER 100 100 100 SER SER D . n 
B 1 101 ARG 101 101 101 ARG ARG D . n 
B 1 102 LYS 102 102 102 LYS LYS D . n 
B 1 103 ALA 103 103 103 ALA ALA D . n 
B 1 104 PRO 104 104 104 PRO PRO D . n 
B 1 105 GLU 105 105 105 GLU GLU D . n 
B 1 106 ALA 106 106 106 ALA ALA D . n 
B 1 107 GLY 107 107 107 GLY GLY D . n 
B 1 108 MET 108 108 108 MET MET D . n 
B 1 109 ARG 109 109 109 ARG ARG D . n 
B 1 110 VAL 110 110 110 VAL VAL D . n 
B 1 111 GLY 111 111 111 GLY GLY D . n 
B 1 112 ARG 112 112 112 ARG ARG D . n 
B 1 113 SER 113 113 113 SER SER D . n 
B 1 114 LEU 114 114 114 LEU LEU D . n 
B 1 115 ILE 115 115 115 ILE ILE D . n 
B 1 116 LEU 116 116 116 LEU LEU D . n 
B 1 117 THR 117 117 117 THR THR D . n 
B 1 118 SER 118 118 118 SER SER D . n 
B 1 119 ARG 119 119 119 ARG ARG D . n 
B 1 120 TRP 120 120 120 TRP TRP D . n 
B 1 121 THR 121 121 121 THR THR D . n 
B 1 122 GLU 122 122 122 GLU GLU D . n 
B 1 123 TYR 123 123 123 TYR TYR D . n 
B 1 124 CYS 124 124 124 CYS CYS D . n 
B 1 125 ALA 125 125 125 ALA ALA D . n 
B 1 126 THR 126 126 126 THR THR D . n 
B 1 127 CYS 127 127 127 CYS CYS D . n 
B 1 128 VAL 128 128 128 VAL VAL D . n 
B 1 129 PRO 129 129 129 PRO PRO D . n 
B 1 130 ALA 130 130 130 ALA ALA D . n 
B 1 131 LEU 131 131 131 LEU LEU D . n 
B 1 132 GLY 132 132 132 GLY GLY D . n 
B 1 133 SER 133 133 133 SER SER D . n 
B 1 134 LYS 134 134 134 LYS LYS D . n 
B 1 135 MET 135 135 135 MET MET D . n 
B 1 136 LYS 136 136 136 LYS LYS D . n 
B 1 137 VAL 137 137 137 VAL VAL D . n 
B 1 138 ILE 138 138 138 ILE ILE D . n 
B 1 139 LYS 139 139 139 LYS LYS D . n 
B 1 140 ALA 140 140 140 ALA ALA D . n 
B 1 141 SER 141 141 141 SER SER D . n 
B 1 142 GLY 142 142 142 GLY GLY D . n 
B 1 143 ASP 143 143 143 ASP ASP D . n 
B 1 144 ALA 144 144 144 ALA ALA D . n 
B 1 145 ALA 145 145 145 ALA ALA D . n 
B 1 146 MET 146 146 146 MET MET D . n 
B 1 147 ILE 147 147 147 ILE ILE D . n 
B 1 148 GLN 148 148 148 GLN GLN D . n 
B 1 149 MET 149 149 149 MET MET D . n 
B 1 150 MET 150 150 150 MET MET D . n 
B 1 151 LYS 151 151 151 LYS LYS D . n 
B 1 152 ASP 152 152 152 ASP ASP D . n 
B 1 153 HIS 153 153 153 HIS HIS D . n 
B 1 154 ASN 154 154 154 ASN ASN D . n 
B 1 155 SER 155 155 155 SER SER D . n 
B 1 156 LEU 156 156 156 LEU LEU D . n 
B 1 157 LEU 157 157 157 LEU LEU D . n 
B 1 158 ARG 158 158 158 ARG ARG D . n 
B 1 159 VAL 159 159 159 VAL VAL D . n 
B 1 160 CYS 160 160 160 CYS CYS D . n 
B 1 161 VAL 161 161 161 VAL VAL D . n 
B 1 162 ARG 162 162 162 ARG ARG D . n 
B 1 163 ILE 163 163 163 ILE ILE D . n 
B 1 164 GLU 164 164 164 GLU GLU D . n 
B 1 165 VAL 165 165 165 VAL VAL D . n 
B 1 166 TRP 166 166 166 TRP TRP D . n 
B 1 167 LYS 167 167 167 LYS LYS D . n 
B 1 168 ALA 168 168 168 ALA ALA D . n 
B 1 169 ARG 169 169 169 ARG ARG D . n 
B 1 170 TYR 170 170 170 TYR TYR D . n 
B 1 171 VAL 171 171 171 VAL VAL D . n 
B 1 172 SER 172 172 172 SER SER D . n 
B 1 173 LEU 173 173 173 LEU LEU D . n 
B 1 174 VAL 174 174 174 VAL VAL D . n 
B 1 175 ALA 175 175 175 ALA ALA D . n 
B 1 176 LEU 176 176 176 LEU LEU D . n 
B 1 177 ASP 177 177 177 ASP ASP D . n 
B 1 178 GLU 178 178 178 GLU GLU D . n 
B 1 179 ARG 179 179 179 ARG ARG D . n 
B 1 180 ILE 180 180 180 ILE ILE D . n 
B 1 181 GLN 181 181 181 GLN GLN D . n 
B 1 182 THR 182 182 182 THR THR D . n 
B 1 183 LEU 183 183 183 LEU LEU D . n 
B 1 184 GLU 184 184 184 GLU GLU D . n 
B 1 185 ASP 185 185 185 ASP ASP D . n 
B 1 186 ALA 186 186 186 ALA ALA D . n 
B 1 187 GLN 187 187 187 GLN GLN D . n 
B 1 188 TRP 188 188 188 TRP TRP D . n 
B 1 189 PHE 189 189 189 PHE PHE D . n 
B 1 190 PRO 190 190 190 PRO PRO D . n 
B 1 191 TYR 191 191 191 TYR TYR D . n 
B 1 192 LEU 192 192 192 LEU LEU D . n 
B 1 193 SER 193 193 193 SER SER D . n 
B 1 194 GLY 194 194 194 GLY GLY D . n 
B 1 195 ASP 195 195 195 ASP ASP D . n 
B 1 196 SER 196 196 196 SER SER D . n 
B 1 197 TYR 197 197 197 TYR TYR D . n 
B 1 198 ARG 198 198 198 ARG ARG D . n 
B 1 199 ALA 199 199 199 ALA ALA D . n 
B 1 200 CYS 200 200 200 CYS CYS D . n 
B 1 201 PRO 201 201 201 PRO PRO D . n 
B 1 202 GLY 202 202 202 GLY GLY D . n 
B 1 203 LEU 203 203 203 LEU LEU D . n 
B 1 204 VAL 204 204 204 VAL VAL D . n 
B 1 205 GLY 205 205 205 GLY GLY D . n 
B 1 206 GLY 206 206 206 GLY GLY D . n 
B 1 207 TYR 207 207 207 TYR TYR D . n 
B 1 208 PHE 208 208 208 PHE PHE D . n 
B 1 209 ALA 209 209 209 ALA ALA D . n 
B 1 210 LYS 210 210 210 LYS LYS D . n 
B 1 211 LYS 211 211 211 LYS LYS D . n 
B 1 212 ALA 212 212 212 ALA ALA D . n 
B 1 213 ALA 213 213 213 ALA ALA D . n 
B 1 214 ALA 214 214 214 ALA ALA D . n 
B 1 215 GLY 215 215 215 GLY GLY D . n 
B 1 216 GLU 216 216 216 GLU GLU D . n 
B 1 217 ARG 217 217 217 ARG ARG D . n 
B 1 218 GLY 218 218 218 GLY GLY D . n 
B 1 219 LYS 219 219 219 LYS LYS D . n 
B 1 220 ASN 220 220 220 ASN ASN D . n 
B 1 221 TYR 221 221 221 TYR TYR D . n 
B 1 222 LYS 222 222 222 LYS LYS D . n 
B 1 223 LYS 223 223 223 LYS LYS D . n 
B 1 224 LEU 224 224 224 LEU LEU D . n 
B 1 225 ASN 225 225 225 ASN ASN D . n 
B 1 226 GLN 226 226 226 GLN GLN D . n 
B 1 227 THR 227 227 227 THR THR D . n 
B 1 228 ALA 228 228 228 ALA ALA D . n 
B 1 229 ILE 229 229 229 ILE ILE D . n 
B 1 230 ILE 230 230 230 ILE ILE D . n 
B 1 231 PRO 231 231 231 PRO PRO D . n 
B 1 232 PRO 232 232 232 PRO PRO D . n 
B 1 233 PRO 233 233 233 PRO PRO D . n 
B 1 234 ARG 234 234 234 ARG ARG D . n 
B 1 235 PHE 235 235 235 PHE PHE D . n 
B 1 236 LEU 236 236 236 LEU LEU D . n 
B 1 237 ILE 237 237 237 ILE ILE D . n 
B 1 238 ILE 238 238 238 ILE ILE D . n 
B 1 239 GLY 239 239 239 GLY GLY D . n 
B 1 240 HIS 240 240 240 HIS HIS D . n 
B 1 241 ARG 241 241 241 ARG ARG D . n 
B 1 242 LEU 242 242 242 LEU LEU D . n 
B 1 243 GLN 243 243 243 GLN GLN D . n 
B 1 244 ILE 244 244 244 ILE ILE D . n 
B 1 245 GLY 245 245 245 GLY GLY D . n 
B 1 246 ASP 246 246 246 ASP ASP D . n 
B 1 247 GLN 247 247 247 GLN GLN D . n 
B 1 248 VAL 248 248 248 VAL VAL D . n 
B 1 249 THR 249 249 249 THR THR D . n 
B 1 250 LEU 250 250 250 LEU LEU D . n 
B 1 251 ARG 251 251 251 ARG ARG D . n 
B 1 252 GLU 252 252 252 GLU GLU D . n 
B 1 253 LEU 253 253 253 LEU LEU D . n 
B 1 254 LEU 254 254 254 LEU LEU D . n 
B 1 255 ALA 255 255 255 ALA ALA D . n 
B 1 256 SER 256 256 256 SER SER D . n 
B 1 257 ILE 257 257 257 ILE ILE D . n 
B 1 258 ALA 258 258 258 ALA ALA D . n 
B 1 259 TRP 259 259 259 TRP TRP D . n 
B 1 260 GLY 260 260 260 GLY GLY D . n 
B 1 261 LEU 261 261 261 LEU LEU D . n 
B 1 262 CYS 262 262 262 CYS CYS D . n 
B 1 263 ASP 263 263 263 ASP ASP D . n 
B 1 264 GLY 264 264 264 GLY GLY D . n 
B 1 265 VAL 265 265 265 VAL VAL D . n 
B 1 266 LEU 266 266 266 LEU LEU D . n 
B 1 267 ALA 267 267 267 ALA ALA D . n 
B 1 268 GLU 268 268 268 GLU GLU D . n 
B 1 269 CYS 269 269 269 CYS CYS D . n 
B 1 270 TRP 270 270 270 TRP TRP D . n 
B 1 271 SER 271 271 271 SER SER D . n 
B 1 272 PRO 272 272 272 PRO PRO D . n 
B 1 273 SER 273 273 273 SER SER D . n 
B 1 274 GLN 274 274 274 GLN GLN D . n 
B 1 275 GLY 275 275 275 GLY GLY D . n 
B 1 276 ASP 276 276 276 ASP ASP D . n 
B 1 277 GLY 277 277 277 GLY GLY D . n 
B 1 278 SER 278 278 278 SER SER D . n 
B 1 279 ILE 279 279 279 ILE ILE D . n 
B 1 280 GLY 280 280 280 GLY GLY D . n 
B 1 281 VAL 281 281 281 VAL VAL D . n 
B 1 282 VAL 282 282 282 VAL VAL D . n 
B 1 283 VAL 283 283 283 VAL VAL D . n 
B 1 284 GLY 284 284 284 GLY GLY D . n 
B 1 285 LEU 285 285 285 LEU LEU D . n 
B 1 286 PRO 286 286 286 PRO PRO D . n 
B 1 287 LEU 287 287 287 LEU LEU D . n 
B 1 288 GLN 288 288 288 GLN GLN D . n 
B 1 289 ALA 289 289 289 ALA ALA D . n 
B 1 290 THR 290 290 290 THR THR D . n 
B 1 291 GLY 291 291 291 GLY GLY D . n 
B 1 292 SER 292 292 292 SER SER D . n 
B 1 293 CYS 293 293 293 CYS CYS D . n 
B 1 294 PHE 294 294 294 PHE PHE D . n 
B 1 295 LEU 295 295 295 LEU LEU D . n 
B 1 296 VAL 296 296 296 VAL VAL D . n 
B 1 297 VAL 297 297 297 VAL VAL D . n 
B 1 298 ALA 298 298 298 ALA ALA D . n 
B 1 299 SER 299 299 299 SER SER D . n 
B 1 300 HIS 300 300 300 HIS HIS D . n 
B 1 301 GLY 301 301 301 GLY GLY D . n 
B 1 302 LEU 302 302 302 LEU LEU D . n 
B 1 303 SER 303 303 303 SER SER D . n 
B 1 304 ALA 304 304 304 ALA ALA D . n 
B 1 305 ILE 305 305 305 ILE ILE D . n 
B 1 306 ALA 306 306 306 ALA ALA D . n 
B 1 307 ASP 307 307 307 ASP ASP D . n 
B 1 308 SER 308 308 308 SER SER D . n 
B 1 309 ARG 309 309 309 ARG ARG D . n 
B 1 310 ILE 310 310 310 ILE ILE D . n 
B 1 311 GLU 311 311 311 GLU GLU D . n 
B 1 312 GLY 312 312 312 GLY GLY D . n 
B 1 313 THR 313 313 313 THR THR D . n 
B 1 314 GLY 314 314 314 GLY GLY D . n 
B 1 315 ASN 315 315 315 ASN ASN D . n 
B 1 316 THR 316 316 316 THR THR D . n 
B 1 317 ASN 317 317 317 ASN ASN D . n 
B 1 318 LEU 318 318 318 LEU LEU D . n 
B 1 319 LEU 319 319 319 LEU LEU D . n 
B 1 320 GLU 320 320 320 GLU GLU D . n 
B 1 321 GLU 321 321 321 GLU GLU D . n 
B 1 322 CYS 322 322 322 CYS CYS D . n 
B 1 323 ILE 323 323 323 ILE ILE D . n 
B 1 324 ALA 324 324 324 ALA ALA D . n 
B 1 325 ILE 325 325 325 ILE ILE D . n 
B 1 326 GLN 326 326 326 GLN GLN D . n 
B 1 327 LYS 327 327 327 LYS LYS D . n 
B 1 328 GLN 328 328 328 GLN GLN D . n 
B 1 329 ASP 329 329 329 ASP ASP D . n 
B 1 330 GLY 330 330 330 GLY GLY D . n 
B 1 331 VAL 331 331 331 VAL VAL D . n 
B 1 332 ILE 332 332 332 ILE ILE D . n 
B 1 333 LYS 333 333 333 LYS LYS D . n 
B 1 334 CYS 334 334 334 CYS CYS D . n 
B 1 335 LYS 335 335 335 LYS LYS D . n 
B 1 336 ARG 336 336 336 ARG ARG D . n 
B 1 337 SER 337 337 337 SER SER D . n 
B 1 338 GLY 338 338 338 GLY GLY D . n 
B 1 339 LYS 339 339 339 LYS LYS D . n 
B 1 340 SER 340 340 340 SER SER D . n 
B 1 341 LEU 341 341 341 LEU LEU D . n 
B 1 342 TYR 342 342 342 TYR TYR D . n 
B 1 343 HIS 343 343 343 HIS HIS D . n 
B 1 344 CYS 344 344 344 CYS CYS D . n 
B 1 345 LEU 345 345 345 LEU LEU D . n 
B 1 346 LYS 346 346 346 LYS LYS D . n 
B 1 347 GLU 347 347 347 GLU GLU D . n 
B 1 348 THR 348 348 348 THR THR D . n 
B 1 349 ALA 349 349 349 ALA ALA D . n 
B 1 350 GLY 350 350 350 GLY GLY D . n 
B 1 351 ALA 351 351 ?   ?   ?   D . n 
B 1 352 VAL 352 352 ?   ?   ?   D . n 
B 1 353 GLY 353 353 ?   ?   ?   D . n 
B 1 354 ARG 354 354 ?   ?   ?   D . n 
C 1 1   MET 1   1   ?   ?   ?   E . n 
C 1 2   VAL 2   2   ?   ?   ?   E . n 
C 1 3   ARG 3   3   ?   ?   ?   E . n 
C 1 4   THR 4   4   ?   ?   ?   E . n 
C 1 5   THR 5   5   ?   ?   ?   E . n 
C 1 6   LYS 6   6   ?   ?   ?   E . n 
C 1 7   THR 7   7   ?   ?   ?   E . n 
C 1 8   SER 8   8   ?   ?   ?   E . n 
C 1 9   MET 9   9   ?   ?   ?   E . n 
C 1 10  ALA 10  10  ?   ?   ?   E . n 
C 1 11  ALA 11  11  ?   ?   ?   E . n 
C 1 12  ALA 12  12  ?   ?   ?   E . n 
C 1 13  SER 13  13  ?   ?   ?   E . n 
C 1 14  THR 14  14  ?   ?   ?   E . n 
C 1 15  VAL 15  15  ?   ?   ?   E . n 
C 1 16  ALA 16  16  ?   ?   ?   E . n 
C 1 17  PRO 17  17  ?   ?   ?   E . n 
C 1 18  GLU 18  18  ?   ?   ?   E . n 
C 1 19  VAL 19  19  ?   ?   ?   E . n 
C 1 20  ALA 20  20  ?   ?   ?   E . n 
C 1 21  MET 21  21  ?   ?   ?   E . n 
C 1 22  ASP 22  22  ?   ?   ?   E . n 
C 1 23  GLU 23  23  ?   ?   ?   E . n 
C 1 24  GLY 24  24  ?   ?   ?   E . n 
C 1 25  SER 25  25  ?   ?   ?   E . n 
C 1 26  PRO 26  26  ?   ?   ?   E . n 
C 1 27  SER 27  27  ?   ?   ?   E . n 
C 1 28  THR 28  28  ?   ?   ?   E . n 
C 1 29  SER 29  29  ?   ?   ?   E . n 
C 1 30  GLN 30  30  ?   ?   ?   E . n 
C 1 31  ALA 31  31  ?   ?   ?   E . n 
C 1 32  GLN 32  32  ?   ?   ?   E . n 
C 1 33  VAL 33  33  ?   ?   ?   E . n 
C 1 34  GLU 34  34  ?   ?   ?   E . n 
C 1 35  LEU 35  35  ?   ?   ?   E . n 
C 1 36  PRO 36  36  ?   ?   ?   E . n 
C 1 37  ARG 37  37  ?   ?   ?   E . n 
C 1 38  ASN 38  38  ?   ?   ?   E . n 
C 1 39  LEU 39  39  ?   ?   ?   E . n 
C 1 40  GLU 40  40  ?   ?   ?   E . n 
C 1 41  VAL 41  41  ?   ?   ?   E . n 
C 1 42  PHE 42  42  ?   ?   ?   E . n 
C 1 43  ASN 43  43  ?   ?   ?   E . n 
C 1 44  GLU 44  44  ?   ?   ?   E . n 
C 1 45  ALA 45  45  ?   ?   ?   E . n 
C 1 46  CYS 46  46  ?   ?   ?   E . n 
C 1 47  GLY 47  47  ?   ?   ?   E . n 
C 1 48  HIS 48  48  ?   ?   ?   E . n 
C 1 49  VAL 49  49  ?   ?   ?   E . n 
C 1 50  PHE 50  50  ?   ?   ?   E . n 
C 1 51  GLY 51  51  ?   ?   ?   E . n 
C 1 52  SER 52  52  ?   ?   ?   E . n 
C 1 53  SER 53  53  ?   ?   ?   E . n 
C 1 54  PHE 54  54  ?   ?   ?   E . n 
C 1 55  ASN 55  55  ?   ?   ?   E . n 
C 1 56  ARG 56  56  ?   ?   ?   E . n 
C 1 57  GLU 57  57  ?   ?   ?   E . n 
C 1 58  ASP 58  58  ?   ?   ?   E . n 
C 1 59  ASN 59  59  ?   ?   ?   E . n 
C 1 60  SER 60  60  ?   ?   ?   E . n 
C 1 61  VAL 61  61  ?   ?   ?   E . n 
C 1 62  ILE 62  62  ?   ?   ?   E . n 
C 1 63  SER 63  63  ?   ?   ?   E . n 
C 1 64  ASP 64  64  ?   ?   ?   E . n 
C 1 65  ALA 65  65  ?   ?   ?   E . n 
C 1 66  ALA 66  66  ?   ?   ?   E . n 
C 1 67  ALA 67  67  ?   ?   ?   E . n 
C 1 68  PHE 68  68  ?   ?   ?   E . n 
C 1 69  LEU 69  69  ?   ?   ?   E . n 
C 1 70  PHE 70  70  ?   ?   ?   E . n 
C 1 71  LYS 71  71  ?   ?   ?   E . n 
C 1 72  MET 72  72  ?   ?   ?   E . n 
C 1 73  HIS 73  73  ?   ?   ?   E . n 
C 1 74  THR 74  74  ?   ?   ?   E . n 
C 1 75  HIS 75  75  ?   ?   ?   E . n 
C 1 76  SER 76  76  ?   ?   ?   E . n 
C 1 77  LEU 77  77  ?   ?   ?   E . n 
C 1 78  ASP 78  78  ?   ?   ?   E . n 
C 1 79  GLY 79  79  ?   ?   ?   E . n 
C 1 80  GLN 80  80  ?   ?   ?   E . n 
C 1 81  GLU 81  81  ?   ?   ?   E . n 
C 1 82  ALA 82  82  ?   ?   ?   E . n 
C 1 83  LYS 83  83  ?   ?   ?   E . n 
C 1 84  VAL 84  84  ?   ?   ?   E . n 
C 1 85  LEU 85  85  ?   ?   ?   E . n 
C 1 86  ARG 86  86  ?   ?   ?   E . n 
C 1 87  ALA 87  87  ?   ?   ?   E . n 
C 1 88  SER 88  88  ?   ?   ?   E . n 
C 1 89  GLU 89  89  ?   ?   ?   E . n 
C 1 90  LYS 90  90  ?   ?   ?   E . n 
C 1 91  LYS 91  91  ?   ?   ?   E . n 
C 1 92  ARG 92  92  ?   ?   ?   E . n 
C 1 93  GLU 93  93  ?   ?   ?   E . n 
C 1 94  ARG 94  94  ?   ?   ?   E . n 
C 1 95  GLU 95  95  ?   ?   ?   E . n 
C 1 96  ASN 96  96  ?   ?   ?   E . n 
C 1 97  ALA 97  97  ?   ?   ?   E . n 
C 1 98  LYS 98  98  ?   ?   ?   E . n 
C 1 99  LYS 99  99  ?   ?   ?   E . n 
C 1 100 SER 100 100 ?   ?   ?   E . n 
C 1 101 ARG 101 101 ?   ?   ?   E . n 
C 1 102 LYS 102 102 ?   ?   ?   E . n 
C 1 103 ALA 103 103 ?   ?   ?   E . n 
C 1 104 PRO 104 104 ?   ?   ?   E . n 
C 1 105 GLU 105 105 ?   ?   ?   E . n 
C 1 106 ALA 106 106 ?   ?   ?   E . n 
C 1 107 GLY 107 107 ?   ?   ?   E . n 
C 1 108 MET 108 108 ?   ?   ?   E . n 
C 1 109 ARG 109 109 ?   ?   ?   E . n 
C 1 110 VAL 110 110 ?   ?   ?   E . n 
C 1 111 GLY 111 111 ?   ?   ?   E . n 
C 1 112 ARG 112 112 ?   ?   ?   E . n 
C 1 113 SER 113 113 ?   ?   ?   E . n 
C 1 114 LEU 114 114 ?   ?   ?   E . n 
C 1 115 ILE 115 115 ?   ?   ?   E . n 
C 1 116 LEU 116 116 ?   ?   ?   E . n 
C 1 117 THR 117 117 ?   ?   ?   E . n 
C 1 118 SER 118 118 ?   ?   ?   E . n 
C 1 119 ARG 119 119 ?   ?   ?   E . n 
C 1 120 TRP 120 120 ?   ?   ?   E . n 
C 1 121 THR 121 121 ?   ?   ?   E . n 
C 1 122 GLU 122 122 ?   ?   ?   E . n 
C 1 123 TYR 123 123 ?   ?   ?   E . n 
C 1 124 CYS 124 124 ?   ?   ?   E . n 
C 1 125 ALA 125 125 ?   ?   ?   E . n 
C 1 126 THR 126 126 ?   ?   ?   E . n 
C 1 127 CYS 127 127 ?   ?   ?   E . n 
C 1 128 VAL 128 128 ?   ?   ?   E . n 
C 1 129 PRO 129 129 ?   ?   ?   E . n 
C 1 130 ALA 130 130 ?   ?   ?   E . n 
C 1 131 LEU 131 131 ?   ?   ?   E . n 
C 1 132 GLY 132 132 ?   ?   ?   E . n 
C 1 133 SER 133 133 ?   ?   ?   E . n 
C 1 134 LYS 134 134 ?   ?   ?   E . n 
C 1 135 MET 135 135 ?   ?   ?   E . n 
C 1 136 LYS 136 136 ?   ?   ?   E . n 
C 1 137 VAL 137 137 ?   ?   ?   E . n 
C 1 138 ILE 138 138 ?   ?   ?   E . n 
C 1 139 LYS 139 139 ?   ?   ?   E . n 
C 1 140 ALA 140 140 ?   ?   ?   E . n 
C 1 141 SER 141 141 ?   ?   ?   E . n 
C 1 142 GLY 142 142 ?   ?   ?   E . n 
C 1 143 ASP 143 143 ?   ?   ?   E . n 
C 1 144 ALA 144 144 ?   ?   ?   E . n 
C 1 145 ALA 145 145 ?   ?   ?   E . n 
C 1 146 MET 146 146 ?   ?   ?   E . n 
C 1 147 ILE 147 147 ?   ?   ?   E . n 
C 1 148 GLN 148 148 ?   ?   ?   E . n 
C 1 149 MET 149 149 ?   ?   ?   E . n 
C 1 150 MET 150 150 ?   ?   ?   E . n 
C 1 151 LYS 151 151 ?   ?   ?   E . n 
C 1 152 ASP 152 152 ?   ?   ?   E . n 
C 1 153 HIS 153 153 ?   ?   ?   E . n 
C 1 154 ASN 154 154 ?   ?   ?   E . n 
C 1 155 SER 155 155 ?   ?   ?   E . n 
C 1 156 LEU 156 156 ?   ?   ?   E . n 
C 1 157 LEU 157 157 ?   ?   ?   E . n 
C 1 158 ARG 158 158 ?   ?   ?   E . n 
C 1 159 VAL 159 159 ?   ?   ?   E . n 
C 1 160 CYS 160 160 ?   ?   ?   E . n 
C 1 161 VAL 161 161 ?   ?   ?   E . n 
C 1 162 ARG 162 162 ?   ?   ?   E . n 
C 1 163 ILE 163 163 ?   ?   ?   E . n 
C 1 164 GLU 164 164 ?   ?   ?   E . n 
C 1 165 VAL 165 165 ?   ?   ?   E . n 
C 1 166 TRP 166 166 ?   ?   ?   E . n 
C 1 167 LYS 167 167 ?   ?   ?   E . n 
C 1 168 ALA 168 168 ?   ?   ?   E . n 
C 1 169 ARG 169 169 ?   ?   ?   E . n 
C 1 170 TYR 170 170 ?   ?   ?   E . n 
C 1 171 VAL 171 171 ?   ?   ?   E . n 
C 1 172 SER 172 172 ?   ?   ?   E . n 
C 1 173 LEU 173 173 ?   ?   ?   E . n 
C 1 174 VAL 174 174 ?   ?   ?   E . n 
C 1 175 ALA 175 175 ?   ?   ?   E . n 
C 1 176 LEU 176 176 ?   ?   ?   E . n 
C 1 177 ASP 177 177 ?   ?   ?   E . n 
C 1 178 GLU 178 178 ?   ?   ?   E . n 
C 1 179 ARG 179 179 ?   ?   ?   E . n 
C 1 180 ILE 180 180 ?   ?   ?   E . n 
C 1 181 GLN 181 181 ?   ?   ?   E . n 
C 1 182 THR 182 182 ?   ?   ?   E . n 
C 1 183 LEU 183 183 ?   ?   ?   E . n 
C 1 184 GLU 184 184 ?   ?   ?   E . n 
C 1 185 ASP 185 185 ?   ?   ?   E . n 
C 1 186 ALA 186 186 ?   ?   ?   E . n 
C 1 187 GLN 187 187 ?   ?   ?   E . n 
C 1 188 TRP 188 188 ?   ?   ?   E . n 
C 1 189 PHE 189 189 ?   ?   ?   E . n 
C 1 190 PRO 190 190 ?   ?   ?   E . n 
C 1 191 TYR 191 191 ?   ?   ?   E . n 
C 1 192 LEU 192 192 ?   ?   ?   E . n 
C 1 193 SER 193 193 ?   ?   ?   E . n 
C 1 194 GLY 194 194 ?   ?   ?   E . n 
C 1 195 ASP 195 195 ?   ?   ?   E . n 
C 1 196 SER 196 196 ?   ?   ?   E . n 
C 1 197 TYR 197 197 ?   ?   ?   E . n 
C 1 198 ARG 198 198 ?   ?   ?   E . n 
C 1 199 ALA 199 199 ?   ?   ?   E . n 
C 1 200 CYS 200 200 ?   ?   ?   E . n 
C 1 201 PRO 201 201 ?   ?   ?   E . n 
C 1 202 GLY 202 202 ?   ?   ?   E . n 
C 1 203 LEU 203 203 ?   ?   ?   E . n 
C 1 204 VAL 204 204 ?   ?   ?   E . n 
C 1 205 GLY 205 205 ?   ?   ?   E . n 
C 1 206 GLY 206 206 ?   ?   ?   E . n 
C 1 207 TYR 207 207 ?   ?   ?   E . n 
C 1 208 PHE 208 208 ?   ?   ?   E . n 
C 1 209 ALA 209 209 ?   ?   ?   E . n 
C 1 210 LYS 210 210 ?   ?   ?   E . n 
C 1 211 LYS 211 211 ?   ?   ?   E . n 
C 1 212 ALA 212 212 ?   ?   ?   E . n 
C 1 213 ALA 213 213 ?   ?   ?   E . n 
C 1 214 ALA 214 214 ?   ?   ?   E . n 
C 1 215 GLY 215 215 ?   ?   ?   E . n 
C 1 216 GLU 216 216 ?   ?   ?   E . n 
C 1 217 ARG 217 217 ?   ?   ?   E . n 
C 1 218 GLY 218 218 ?   ?   ?   E . n 
C 1 219 LYS 219 219 ?   ?   ?   E . n 
C 1 220 ASN 220 220 ?   ?   ?   E . n 
C 1 221 TYR 221 221 ?   ?   ?   E . n 
C 1 222 LYS 222 222 ?   ?   ?   E . n 
C 1 223 LYS 223 223 ?   ?   ?   E . n 
C 1 224 LEU 224 224 ?   ?   ?   E . n 
C 1 225 ASN 225 225 ?   ?   ?   E . n 
C 1 226 GLN 226 226 ?   ?   ?   E . n 
C 1 227 THR 227 227 ?   ?   ?   E . n 
C 1 228 ALA 228 228 ?   ?   ?   E . n 
C 1 229 ILE 229 229 ?   ?   ?   E . n 
C 1 230 ILE 230 230 ?   ?   ?   E . n 
C 1 231 PRO 231 231 ?   ?   ?   E . n 
C 1 232 PRO 232 232 ?   ?   ?   E . n 
C 1 233 PRO 233 233 ?   ?   ?   E . n 
C 1 234 ARG 234 234 ?   ?   ?   E . n 
C 1 235 PHE 235 235 ?   ?   ?   E . n 
C 1 236 LEU 236 236 ?   ?   ?   E . n 
C 1 237 ILE 237 237 ?   ?   ?   E . n 
C 1 238 ILE 238 238 ?   ?   ?   E . n 
C 1 239 GLY 239 239 ?   ?   ?   E . n 
C 1 240 HIS 240 240 ?   ?   ?   E . n 
C 1 241 ARG 241 241 ?   ?   ?   E . n 
C 1 242 LEU 242 242 ?   ?   ?   E . n 
C 1 243 GLN 243 243 ?   ?   ?   E . n 
C 1 244 ILE 244 244 ?   ?   ?   E . n 
C 1 245 GLY 245 245 ?   ?   ?   E . n 
C 1 246 ASP 246 246 ?   ?   ?   E . n 
C 1 247 GLN 247 247 ?   ?   ?   E . n 
C 1 248 VAL 248 248 ?   ?   ?   E . n 
C 1 249 THR 249 249 ?   ?   ?   E . n 
C 1 250 LEU 250 250 ?   ?   ?   E . n 
C 1 251 ARG 251 251 ?   ?   ?   E . n 
C 1 252 GLU 252 252 ?   ?   ?   E . n 
C 1 253 LEU 253 253 ?   ?   ?   E . n 
C 1 254 LEU 254 254 ?   ?   ?   E . n 
C 1 255 ALA 255 255 ?   ?   ?   E . n 
C 1 256 SER 256 256 ?   ?   ?   E . n 
C 1 257 ILE 257 257 ?   ?   ?   E . n 
C 1 258 ALA 258 258 ?   ?   ?   E . n 
C 1 259 TRP 259 259 ?   ?   ?   E . n 
C 1 260 GLY 260 260 ?   ?   ?   E . n 
C 1 261 LEU 261 261 ?   ?   ?   E . n 
C 1 262 CYS 262 262 ?   ?   ?   E . n 
C 1 263 ASP 263 263 ?   ?   ?   E . n 
C 1 264 GLY 264 264 ?   ?   ?   E . n 
C 1 265 VAL 265 265 ?   ?   ?   E . n 
C 1 266 LEU 266 266 ?   ?   ?   E . n 
C 1 267 ALA 267 267 ?   ?   ?   E . n 
C 1 268 GLU 268 268 ?   ?   ?   E . n 
C 1 269 CYS 269 269 ?   ?   ?   E . n 
C 1 270 TRP 270 270 ?   ?   ?   E . n 
C 1 271 SER 271 271 ?   ?   ?   E . n 
C 1 272 PRO 272 272 ?   ?   ?   E . n 
C 1 273 SER 273 273 ?   ?   ?   E . n 
C 1 274 GLN 274 274 ?   ?   ?   E . n 
C 1 275 GLY 275 275 ?   ?   ?   E . n 
C 1 276 ASP 276 276 ?   ?   ?   E . n 
C 1 277 GLY 277 277 ?   ?   ?   E . n 
C 1 278 SER 278 278 ?   ?   ?   E . n 
C 1 279 ILE 279 279 ?   ?   ?   E . n 
C 1 280 GLY 280 280 ?   ?   ?   E . n 
C 1 281 VAL 281 281 ?   ?   ?   E . n 
C 1 282 VAL 282 282 ?   ?   ?   E . n 
C 1 283 VAL 283 283 ?   ?   ?   E . n 
C 1 284 GLY 284 284 ?   ?   ?   E . n 
C 1 285 LEU 285 285 ?   ?   ?   E . n 
C 1 286 PRO 286 286 ?   ?   ?   E . n 
C 1 287 LEU 287 287 ?   ?   ?   E . n 
C 1 288 GLN 288 288 ?   ?   ?   E . n 
C 1 289 ALA 289 289 ?   ?   ?   E . n 
C 1 290 THR 290 290 ?   ?   ?   E . n 
C 1 291 GLY 291 291 291 GLY GLY E . n 
C 1 292 SER 292 292 292 SER SER E . n 
C 1 293 CYS 293 293 293 CYS CYS E . n 
C 1 294 PHE 294 294 294 PHE PHE E . n 
C 1 295 LEU 295 295 295 LEU LEU E . n 
C 1 296 VAL 296 296 296 VAL VAL E . n 
C 1 297 VAL 297 297 297 VAL VAL E . n 
C 1 298 ALA 298 298 298 ALA ALA E . n 
C 1 299 SER 299 299 299 SER SER E . n 
C 1 300 HIS 300 300 300 HIS HIS E . n 
C 1 301 GLY 301 301 301 GLY GLY E . n 
C 1 302 LEU 302 302 302 LEU LEU E . n 
C 1 303 SER 303 303 303 SER SER E . n 
C 1 304 ALA 304 304 304 ALA ALA E . n 
C 1 305 ILE 305 305 305 ILE ILE E . n 
C 1 306 ALA 306 306 306 ALA ALA E . n 
C 1 307 ASP 307 307 307 ASP ASP E . n 
C 1 308 SER 308 308 308 SER SER E . n 
C 1 309 ARG 309 309 309 ARG ARG E . n 
C 1 310 ILE 310 310 310 ILE ILE E . n 
C 1 311 GLU 311 311 311 GLU GLU E . n 
C 1 312 GLY 312 312 ?   ?   ?   E . n 
C 1 313 THR 313 313 ?   ?   ?   E . n 
C 1 314 GLY 314 314 ?   ?   ?   E . n 
C 1 315 ASN 315 315 ?   ?   ?   E . n 
C 1 316 THR 316 316 ?   ?   ?   E . n 
C 1 317 ASN 317 317 ?   ?   ?   E . n 
C 1 318 LEU 318 318 ?   ?   ?   E . n 
C 1 319 LEU 319 319 ?   ?   ?   E . n 
C 1 320 GLU 320 320 ?   ?   ?   E . n 
C 1 321 GLU 321 321 ?   ?   ?   E . n 
C 1 322 CYS 322 322 ?   ?   ?   E . n 
C 1 323 ILE 323 323 ?   ?   ?   E . n 
C 1 324 ALA 324 324 ?   ?   ?   E . n 
C 1 325 ILE 325 325 ?   ?   ?   E . n 
C 1 326 GLN 326 326 ?   ?   ?   E . n 
C 1 327 LYS 327 327 ?   ?   ?   E . n 
C 1 328 GLN 328 328 ?   ?   ?   E . n 
C 1 329 ASP 329 329 ?   ?   ?   E . n 
C 1 330 GLY 330 330 ?   ?   ?   E . n 
C 1 331 VAL 331 331 ?   ?   ?   E . n 
C 1 332 ILE 332 332 ?   ?   ?   E . n 
C 1 333 LYS 333 333 ?   ?   ?   E . n 
C 1 334 CYS 334 334 ?   ?   ?   E . n 
C 1 335 LYS 335 335 ?   ?   ?   E . n 
C 1 336 ARG 336 336 ?   ?   ?   E . n 
C 1 337 SER 337 337 ?   ?   ?   E . n 
C 1 338 GLY 338 338 ?   ?   ?   E . n 
C 1 339 LYS 339 339 ?   ?   ?   E . n 
C 1 340 SER 340 340 ?   ?   ?   E . n 
C 1 341 LEU 341 341 ?   ?   ?   E . n 
C 1 342 TYR 342 342 ?   ?   ?   E . n 
C 1 343 HIS 343 343 ?   ?   ?   E . n 
C 1 344 CYS 344 344 ?   ?   ?   E . n 
C 1 345 LEU 345 345 ?   ?   ?   E . n 
C 1 346 LYS 346 346 ?   ?   ?   E . n 
C 1 347 GLU 347 347 ?   ?   ?   E . n 
C 1 348 THR 348 348 ?   ?   ?   E . n 
C 1 349 ALA 349 349 ?   ?   ?   E . n 
C 1 350 GLY 350 350 ?   ?   ?   E . n 
C 1 351 ALA 351 351 ?   ?   ?   E . n 
C 1 352 VAL 352 352 ?   ?   ?   E . n 
C 1 353 GLY 353 353 ?   ?   ?   E . n 
C 1 354 ARG 354 354 ?   ?   ?   E . n 
D 2 1   P5P 1   3   3   P5P P5P O . n 
D 2 2   P5P 2   4   4   P5P P5P O . n 
D 2 3   P5P 3   5   5   P5P P5P O . n 
D 2 4   P5P 4   6   6   P5P P5P O . n 
D 2 5   P5P 5   7   7   P5P P5P O . n 
D 2 6   Y5P 6   8   8   Y5P Y5P O . n 
D 2 7   Y5P 7   9   9   Y5P Y5P O . n 
D 2 8   P5P 8   10  10  P5P P5P O . n 
D 2 9   P5P 9   11  11  P5P P5P O . n 
D 2 10  Y5P 10  12  12  Y5P Y5P O . n 
E 3 1   Y5P 1   10  10  Y5P Y5P N . n 
E 3 2   Y5P 2   11  11  Y5P Y5P N . n 
E 3 3   Y5P 3   12  12  Y5P Y5P N . n 
E 3 4   Y5P 4   13  13  Y5P Y5P N . n 
E 3 5   Y5P 5   14  14  Y5P Y5P N . n 
E 3 6   P5P 6   15  15  P5P P5P N . n 
E 3 7   Y5P 7   28  28  Y5P Y5P N . n 
E 3 8   P5P 8   29  29  P5P P5P N . n 
E 3 9   P5P 9   30  30  P5P P5P N . n 
E 3 10  P5P 10  31  31  P5P P5P N . n 
E 3 11  P5P 11  32  32  P5P P5P N . n 
E 3 12  P5P 12  33  33  P5P P5P N . n 
E 3 13  P5P 13  34  34  P5P P5P N . n 
E 3 14  P5P 14  35  35  P5P P5P N . n 
E 3 15  P5P 15  36  36  P5P P5P N . n 
E 3 16  Y5P 16  37  37  Y5P Y5P N . n 
E 3 17  Y5P 17  38  38  Y5P Y5P N . n 
E 3 18  Y5P 18  39  39  Y5P Y5P N . n 
E 3 19  P5P 19  40  40  P5P P5P N . n 
E 3 20  Y5P 20  41  41  Y5P Y5P N . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 P5P ? ? P5P ? ? 'SUBJECT OF INVESTIGATION' ? 
2 Y5P ? ? Y5P ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 C GLU 34 ? CG  ? A GLU 34 CG  
2 1 Y 1 C GLU 34 ? CD  ? A GLU 34 CD  
3 1 Y 1 C GLU 34 ? OE1 ? A GLU 34 OE1 
4 1 Y 1 C GLU 34 ? OE2 ? A GLU 34 OE2 
5 1 Y 1 D GLU 34 ? CG  ? B GLU 34 CG  
6 1 Y 1 D GLU 34 ? CD  ? B GLU 34 CD  
7 1 Y 1 D GLU 34 ? OE1 ? B GLU 34 OE1 
8 1 Y 1 D GLU 34 ? OE2 ? B GLU 34 OE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9HBV 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9HBV 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9HBV 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9HBV 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.002  ? 5606 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.393  ? 7690 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 10.962 ? 1054 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.034  ? 885  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.003  ? 876  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9HBV 
_struct.title                        'TiLV-NP tetramer (pseudo-C4) (local refinement around 2 TiLV-NPs)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9HBV 
_struct_keywords.text            'Viral protein, nucleoprotein, oligomer, RNA BINDING PROTEIN' 
_struct_keywords.pdbx_keywords   'RNA BINDING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP A0A1Y9SHW7_9VIRU A0A1Y9SHW7 ? 1 
;MVRTTKTSMAAASTVAPEVAMDEGSPSTSQAQVELPRNLEVFNEACGHVFGSSFNREDNSVISDAAAFLFKMHTHSLDGQ
EAKVLRASEKKRERENAKKSRKAPEAGMRVGRSLILTSRWTEYCATCVPALGSKMKVIKASGDAAMIQMMKDHNSLLRVC
VRIEVWKARYVSLVALDERIQTLEDAQWFPYLSGDSYRACPGLVGGYFAKKAAAGERGKNYKKLNQTAIIPPPRFLIIGH
RLQIGDQVTLRELLASIAWGLCDGVLAECWSPSQGDGSIGVVVGLPLQATGSCFLVVASHGLSAIADSRIEGTGNTNLLE
ECIAIQKQDGVIKCKRSGKSLYHCLKETAGAVGR
;
1 
2 PDB 9HBV             9HBV       ? 2 ? 1 
3 PDB 9HBV             9HBV       ? 3 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9HBV C 1 ? 354 ? A0A1Y9SHW7 1  ? 354 ? 1  354 
2 1 9HBV D 1 ? 354 ? A0A1Y9SHW7 1  ? 354 ? 1  354 
3 1 9HBV E 1 ? 354 ? A0A1Y9SHW7 1  ? 354 ? 1  354 
4 2 9HBV O 1 ? 10  ? 9HBV       3  ? 12  ? 3  12  
5 3 9HBV N 1 ? 20  ? 9HBV       10 ? 41  ? 10 41  
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 36  ? GLY A 51  ? PRO C 36  GLY C 51  1 ? 16 
HELX_P HELX_P2  AA2 SER A 52  ? PHE A 54  ? SER C 52  PHE C 54  5 ? 3  
HELX_P HELX_P3  AA3 ASP A 58  ? THR A 74  ? ASP C 58  THR C 74  1 ? 17 
HELX_P HELX_P4  AA4 SER A 88  ? ARG A 101 ? SER C 88  ARG C 101 1 ? 14 
HELX_P HELX_P5  AA5 ARG A 119 ? VAL A 128 ? ARG C 119 VAL C 128 1 ? 10 
HELX_P HELX_P6  AA6 LYS A 134 ? GLY A 142 ? LYS C 134 GLY C 142 1 ? 9  
HELX_P HELX_P7  AA7 ASP A 143 ? LEU A 173 ? ASP C 143 LEU C 173 1 ? 31 
HELX_P HELX_P8  AA8 THR A 182 ? GLN A 187 ? THR C 182 GLN C 187 1 ? 6  
HELX_P HELX_P9  AA9 SER A 193 ? CYS A 200 ? SER C 193 CYS C 200 1 ? 8  
HELX_P HELX_P10 AB1 GLY A 205 ? ALA A 214 ? GLY C 205 ALA C 214 1 ? 10 
HELX_P HELX_P11 AB2 PRO A 232 ? ILE A 237 ? PRO C 232 ILE C 237 1 ? 6  
HELX_P HELX_P12 AB3 THR A 249 ? ALA A 258 ? THR C 249 ALA C 258 1 ? 10 
HELX_P HELX_P13 AB4 ASP A 263 ? GLU A 268 ? ASP C 263 GLU C 268 5 ? 6  
HELX_P HELX_P14 AB5 ASN A 317 ? GLU A 321 ? ASN C 317 GLU C 321 1 ? 5  
HELX_P HELX_P15 AB6 SER A 340 ? ALA A 349 ? SER C 340 ALA C 349 1 ? 10 
HELX_P HELX_P16 AB7 PRO B 36  ? GLY B 51  ? PRO D 36  GLY D 51  1 ? 16 
HELX_P HELX_P17 AB8 SER B 52  ? PHE B 54  ? SER D 52  PHE D 54  5 ? 3  
HELX_P HELX_P18 AB9 ASP B 58  ? THR B 74  ? ASP D 58  THR D 74  1 ? 17 
HELX_P HELX_P19 AC1 SER B 88  ? ARG B 101 ? SER D 88  ARG D 101 1 ? 14 
HELX_P HELX_P20 AC2 ARG B 119 ? VAL B 128 ? ARG D 119 VAL D 128 1 ? 10 
HELX_P HELX_P21 AC3 LYS B 134 ? GLY B 142 ? LYS D 134 GLY D 142 1 ? 9  
HELX_P HELX_P22 AC4 ASP B 143 ? ALA B 175 ? ASP D 143 ALA D 175 1 ? 33 
HELX_P HELX_P23 AC5 THR B 182 ? GLN B 187 ? THR D 182 GLN D 187 1 ? 6  
HELX_P HELX_P24 AC6 SER B 193 ? CYS B 200 ? SER D 193 CYS D 200 1 ? 8  
HELX_P HELX_P25 AC7 GLY B 206 ? GLY B 215 ? GLY D 206 GLY D 215 1 ? 10 
HELX_P HELX_P26 AC8 PRO B 232 ? ILE B 237 ? PRO D 232 ILE D 237 1 ? 6  
HELX_P HELX_P27 AC9 THR B 249 ? ALA B 258 ? THR D 249 ALA D 258 1 ? 10 
HELX_P HELX_P28 AD1 ASP B 263 ? GLU B 268 ? ASP D 263 GLU D 268 5 ? 6  
HELX_P HELX_P29 AD2 ASP B 307 ? GLY B 312 ? ASP D 307 GLY D 312 1 ? 6  
HELX_P HELX_P30 AD3 SER B 340 ? ALA B 349 ? SER D 340 ALA D 349 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1  covale both ? D P5P 1  "O3'" ? ? ? 1_555 D P5P 2  P ? ? O P5P 3  O P5P 4  1_555 ? ? ? ? ? ? ? 1.608 ? ? 
covale2  covale both ? D P5P 2  "O3'" ? ? ? 1_555 D P5P 3  P ? ? O P5P 4  O P5P 5  1_555 ? ? ? ? ? ? ? 1.608 ? ? 
covale3  covale both ? D P5P 3  "O3'" ? ? ? 1_555 D P5P 4  P ? ? O P5P 5  O P5P 6  1_555 ? ? ? ? ? ? ? 1.607 ? ? 
covale4  covale both ? D P5P 4  "O3'" ? ? ? 1_555 D P5P 5  P ? ? O P5P 6  O P5P 7  1_555 ? ? ? ? ? ? ? 1.605 ? ? 
covale5  covale both ? D P5P 5  "O3'" ? ? ? 1_555 D Y5P 6  P ? ? O P5P 7  O Y5P 8  1_555 ? ? ? ? ? ? ? 1.605 ? ? 
covale6  covale one  ? D Y5P 6  "O3'" ? ? ? 1_555 D Y5P 7  P ? ? O Y5P 8  O Y5P 9  1_555 ? ? ? ? ? ? ? 1.606 ? ? 
covale7  covale one  ? D Y5P 7  "O3'" ? ? ? 1_555 D P5P 8  P ? ? O Y5P 9  O P5P 10 1_555 ? ? ? ? ? ? ? 1.607 ? ? 
covale8  covale both ? D P5P 8  "O3'" ? ? ? 1_555 D P5P 9  P ? ? O P5P 10 O P5P 11 1_555 ? ? ? ? ? ? ? 1.608 ? ? 
covale9  covale both ? D P5P 9  "O3'" ? ? ? 1_555 D Y5P 10 P ? ? O P5P 11 O Y5P 12 1_555 ? ? ? ? ? ? ? 1.607 ? ? 
covale10 covale one  ? E Y5P 1  "O3'" ? ? ? 1_555 E Y5P 2  P ? ? N Y5P 10 N Y5P 11 1_555 ? ? ? ? ? ? ? 1.608 ? ? 
covale11 covale one  ? E Y5P 2  "O3'" ? ? ? 1_555 E Y5P 3  P ? ? N Y5P 11 N Y5P 12 1_555 ? ? ? ? ? ? ? 1.607 ? ? 
covale12 covale one  ? E Y5P 3  "O3'" ? ? ? 1_555 E Y5P 4  P ? ? N Y5P 12 N Y5P 13 1_555 ? ? ? ? ? ? ? 1.607 ? ? 
covale13 covale one  ? E Y5P 4  "O3'" ? ? ? 1_555 E Y5P 5  P ? ? N Y5P 13 N Y5P 14 1_555 ? ? ? ? ? ? ? 1.608 ? ? 
covale14 covale one  ? E Y5P 5  "O3'" ? ? ? 1_555 E P5P 6  P ? ? N Y5P 14 N P5P 15 1_555 ? ? ? ? ? ? ? 1.608 ? ? 
covale15 covale one  ? E Y5P 7  "O3'" ? ? ? 1_555 E P5P 8  P ? ? N Y5P 28 N P5P 29 1_555 ? ? ? ? ? ? ? 1.608 ? ? 
covale16 covale both ? E P5P 8  "O3'" ? ? ? 1_555 E P5P 9  P ? ? N P5P 29 N P5P 30 1_555 ? ? ? ? ? ? ? 1.610 ? ? 
covale17 covale both ? E P5P 9  "O3'" ? ? ? 1_555 E P5P 10 P ? ? N P5P 30 N P5P 31 1_555 ? ? ? ? ? ? ? 1.608 ? ? 
covale18 covale both ? E P5P 10 "O3'" ? ? ? 1_555 E P5P 11 P ? ? N P5P 31 N P5P 32 1_555 ? ? ? ? ? ? ? 1.606 ? ? 
covale19 covale both ? E P5P 11 "O3'" ? ? ? 1_555 E P5P 12 P ? ? N P5P 32 N P5P 33 1_555 ? ? ? ? ? ? ? 1.608 ? ? 
covale20 covale both ? E P5P 12 "O3'" ? ? ? 1_555 E P5P 13 P ? ? N P5P 33 N P5P 34 1_555 ? ? ? ? ? ? ? 1.609 ? ? 
covale21 covale both ? E P5P 13 "O3'" ? ? ? 1_555 E P5P 14 P ? ? N P5P 34 N P5P 35 1_555 ? ? ? ? ? ? ? 1.608 ? ? 
covale22 covale both ? E P5P 14 "O3'" ? ? ? 1_555 E P5P 15 P ? ? N P5P 35 N P5P 36 1_555 ? ? ? ? ? ? ? 1.609 ? ? 
covale23 covale both ? E P5P 15 "O3'" ? ? ? 1_555 E Y5P 16 P ? ? N P5P 36 N Y5P 37 1_555 ? ? ? ? ? ? ? 1.607 ? ? 
covale24 covale one  ? E Y5P 16 "O3'" ? ? ? 1_555 E Y5P 17 P ? ? N Y5P 37 N Y5P 38 1_555 ? ? ? ? ? ? ? 1.604 ? ? 
covale25 covale one  ? E Y5P 17 "O3'" ? ? ? 1_555 E Y5P 18 P ? ? N Y5P 38 N Y5P 39 1_555 ? ? ? ? ? ? ? 1.606 ? ? 
covale26 covale one  ? E Y5P 18 "O3'" ? ? ? 1_555 E P5P 19 P ? ? N Y5P 39 N P5P 40 1_555 ? ? ? ? ? ? ? 1.606 ? ? 
covale27 covale both ? E P5P 19 "O3'" ? ? ? 1_555 E Y5P 20 P ? ? N P5P 40 N Y5P 41 1_555 ? ? ? ? ? ? ? 1.607 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 189 A . ? PHE 189 C PRO 190 A ? PRO 190 C 1 -1.67 
2 PHE 189 B . ? PHE 189 D PRO 190 B ? PRO 190 D 1 -4.30 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 3 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG A 109 ? VAL A 110 ? ARG C 109 VAL C 110 
AA1 2 LEU A 114 ? ILE A 115 ? LEU C 114 ILE C 115 
AA2 1 TRP A 270 ? PRO A 272 ? TRP C 270 PRO C 272 
AA2 2 GLY A 280 ? VAL A 282 ? GLY C 280 VAL C 282 
AA3 1 GLY A 284 ? PRO A 286 ? GLY C 284 PRO C 286 
AA3 2 CYS A 322 ? LYS A 327 ? CYS C 322 LYS C 327 
AA3 3 VAL A 331 ? LYS A 335 ? VAL C 331 LYS C 335 
AA4 1 ARG B 109 ? VAL B 110 ? ARG D 109 VAL D 110 
AA4 2 LEU B 114 ? ILE B 115 ? LEU D 114 ILE D 115 
AA5 1 TRP B 270 ? SER B 271 ? TRP D 270 SER D 271 
AA5 2 VAL B 281 ? VAL B 282 ? VAL D 281 VAL D 282 
AA6 1 LEU B 285 ? PRO B 286 ? LEU D 285 PRO D 286 
AA6 2 CYS B 322 ? GLN B 326 ? CYS D 322 GLN D 326 
AA6 3 VAL B 331 ? LYS B 335 ? VAL D 331 LYS D 335 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 110 ? N VAL C 110 O LEU A 114 ? O LEU C 114 
AA2 1 2 N SER A 271 ? N SER C 271 O VAL A 281 ? O VAL C 281 
AA3 1 2 N LEU A 285 ? N LEU C 285 O GLN A 326 ? O GLN C 326 
AA3 2 3 N ILE A 323 ? N ILE C 323 O CYS A 334 ? O CYS C 334 
AA4 1 2 N VAL B 110 ? N VAL D 110 O LEU B 114 ? O LEU D 114 
AA5 1 2 N SER B 271 ? N SER D 271 O VAL B 281 ? O VAL D 281 
AA6 1 2 N LEU B 285 ? N LEU D 285 O GLN B 326 ? O GLN D 326 
AA6 2 3 N ILE B 325 ? N ILE D 325 O ILE B 332 ? O ILE D 332 
# 
_pdbx_entry_details.entry_id                   9HBV 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OG1 C THR 182 ? ? OD2 C ASP 185 ? ? 1.97 
2 1 O   C ASP 185 ? ? OH  C TYR 191 ? ? 2.08 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ARG C 86  ? ? -141.28 29.85   
2 1 ALA C 258 ? ? -161.11 -169.28 
3 1 ASP C 276 ? ? 58.30   -97.99  
4 1 ASP D 276 ? ? 59.64   -95.38  
5 1 PRO D 286 ? ? -57.49  170.38  
6 1 THR D 316 ? ? -97.07  58.19   
# 
_pdbx_validate_polymer_linkage.id               1 
_pdbx_validate_polymer_linkage.PDB_model_num    1 
_pdbx_validate_polymer_linkage.auth_atom_id_1   "O3'" 
_pdbx_validate_polymer_linkage.auth_asym_id_1   N 
_pdbx_validate_polymer_linkage.auth_comp_id_1   P5P 
_pdbx_validate_polymer_linkage.auth_seq_id_1    15 
_pdbx_validate_polymer_linkage.PDB_ins_code_1   ? 
_pdbx_validate_polymer_linkage.label_alt_id_1   ? 
_pdbx_validate_polymer_linkage.auth_atom_id_2   P 
_pdbx_validate_polymer_linkage.auth_asym_id_2   N 
_pdbx_validate_polymer_linkage.auth_comp_id_2   Y5P 
_pdbx_validate_polymer_linkage.auth_seq_id_2    28 
_pdbx_validate_polymer_linkage.PDB_ins_code_2   ? 
_pdbx_validate_polymer_linkage.label_alt_id_2   ? 
_pdbx_validate_polymer_linkage.dist             17.19 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9HBV 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9HBV 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.38 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               97514 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'TiLV-NP bound to the 40-mer vRNA loop' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1,2,3 
# 
_em_imaging.entry_id                        9HBV 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9HBV 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9HBV 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9HBV 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 C MET 1   ? A MET 1   
2   1 Y 1 C VAL 2   ? A VAL 2   
3   1 Y 1 C ARG 3   ? A ARG 3   
4   1 Y 1 C THR 4   ? A THR 4   
5   1 Y 1 C THR 5   ? A THR 5   
6   1 Y 1 C LYS 6   ? A LYS 6   
7   1 Y 1 C THR 7   ? A THR 7   
8   1 Y 1 C SER 8   ? A SER 8   
9   1 Y 1 C MET 9   ? A MET 9   
10  1 Y 1 C ALA 10  ? A ALA 10  
11  1 Y 1 C ALA 11  ? A ALA 11  
12  1 Y 1 C ALA 12  ? A ALA 12  
13  1 Y 1 C SER 13  ? A SER 13  
14  1 Y 1 C THR 14  ? A THR 14  
15  1 Y 1 C VAL 15  ? A VAL 15  
16  1 Y 1 C ALA 16  ? A ALA 16  
17  1 Y 1 C PRO 17  ? A PRO 17  
18  1 Y 1 C GLU 18  ? A GLU 18  
19  1 Y 1 C VAL 19  ? A VAL 19  
20  1 Y 1 C ALA 20  ? A ALA 20  
21  1 Y 1 C MET 21  ? A MET 21  
22  1 Y 1 C ASP 22  ? A ASP 22  
23  1 Y 1 C GLU 23  ? A GLU 23  
24  1 Y 1 C GLY 24  ? A GLY 24  
25  1 Y 1 C SER 25  ? A SER 25  
26  1 Y 1 C PRO 26  ? A PRO 26  
27  1 Y 1 C SER 27  ? A SER 27  
28  1 Y 1 C THR 28  ? A THR 28  
29  1 Y 1 C SER 29  ? A SER 29  
30  1 Y 1 C GLN 30  ? A GLN 30  
31  1 Y 1 C ALA 31  ? A ALA 31  
32  1 Y 1 C GLN 32  ? A GLN 32  
33  1 Y 1 C VAL 33  ? A VAL 33  
34  1 Y 1 C THR 290 ? A THR 290 
35  1 Y 1 C GLY 291 ? A GLY 291 
36  1 Y 1 C SER 292 ? A SER 292 
37  1 Y 1 C CYS 293 ? A CYS 293 
38  1 Y 1 C PHE 294 ? A PHE 294 
39  1 Y 1 C LEU 295 ? A LEU 295 
40  1 Y 1 C VAL 296 ? A VAL 296 
41  1 Y 1 C VAL 297 ? A VAL 297 
42  1 Y 1 C ALA 298 ? A ALA 298 
43  1 Y 1 C SER 299 ? A SER 299 
44  1 Y 1 C HIS 300 ? A HIS 300 
45  1 Y 1 C GLY 301 ? A GLY 301 
46  1 Y 1 C LEU 302 ? A LEU 302 
47  1 Y 1 C SER 303 ? A SER 303 
48  1 Y 1 C ALA 304 ? A ALA 304 
49  1 Y 1 C ILE 305 ? A ILE 305 
50  1 Y 1 C ALA 306 ? A ALA 306 
51  1 Y 1 C ASP 307 ? A ASP 307 
52  1 Y 1 C SER 308 ? A SER 308 
53  1 Y 1 C ARG 309 ? A ARG 309 
54  1 Y 1 C ILE 310 ? A ILE 310 
55  1 Y 1 C GLU 311 ? A GLU 311 
56  1 Y 1 C GLY 312 ? A GLY 312 
57  1 Y 1 C THR 313 ? A THR 313 
58  1 Y 1 C GLY 314 ? A GLY 314 
59  1 Y 1 C ASN 315 ? A ASN 315 
60  1 Y 1 C ALA 351 ? A ALA 351 
61  1 Y 1 C VAL 352 ? A VAL 352 
62  1 Y 1 C GLY 353 ? A GLY 353 
63  1 Y 1 C ARG 354 ? A ARG 354 
64  1 Y 1 D MET 1   ? B MET 1   
65  1 Y 1 D VAL 2   ? B VAL 2   
66  1 Y 1 D ARG 3   ? B ARG 3   
67  1 Y 1 D THR 4   ? B THR 4   
68  1 Y 1 D THR 5   ? B THR 5   
69  1 Y 1 D LYS 6   ? B LYS 6   
70  1 Y 1 D THR 7   ? B THR 7   
71  1 Y 1 D SER 8   ? B SER 8   
72  1 Y 1 D MET 9   ? B MET 9   
73  1 Y 1 D ALA 10  ? B ALA 10  
74  1 Y 1 D ALA 11  ? B ALA 11  
75  1 Y 1 D ALA 12  ? B ALA 12  
76  1 Y 1 D SER 13  ? B SER 13  
77  1 Y 1 D THR 14  ? B THR 14  
78  1 Y 1 D VAL 15  ? B VAL 15  
79  1 Y 1 D ALA 16  ? B ALA 16  
80  1 Y 1 D PRO 17  ? B PRO 17  
81  1 Y 1 D GLU 18  ? B GLU 18  
82  1 Y 1 D VAL 19  ? B VAL 19  
83  1 Y 1 D ALA 20  ? B ALA 20  
84  1 Y 1 D MET 21  ? B MET 21  
85  1 Y 1 D ASP 22  ? B ASP 22  
86  1 Y 1 D GLU 23  ? B GLU 23  
87  1 Y 1 D GLY 24  ? B GLY 24  
88  1 Y 1 D SER 25  ? B SER 25  
89  1 Y 1 D PRO 26  ? B PRO 26  
90  1 Y 1 D SER 27  ? B SER 27  
91  1 Y 1 D THR 28  ? B THR 28  
92  1 Y 1 D SER 29  ? B SER 29  
93  1 Y 1 D GLN 30  ? B GLN 30  
94  1 Y 1 D ALA 31  ? B ALA 31  
95  1 Y 1 D GLN 32  ? B GLN 32  
96  1 Y 1 D VAL 33  ? B VAL 33  
97  1 Y 1 D ALA 351 ? B ALA 351 
98  1 Y 1 D VAL 352 ? B VAL 352 
99  1 Y 1 D GLY 353 ? B GLY 353 
100 1 Y 1 D ARG 354 ? B ARG 354 
101 1 Y 1 E MET 1   ? C MET 1   
102 1 Y 1 E VAL 2   ? C VAL 2   
103 1 Y 1 E ARG 3   ? C ARG 3   
104 1 Y 1 E THR 4   ? C THR 4   
105 1 Y 1 E THR 5   ? C THR 5   
106 1 Y 1 E LYS 6   ? C LYS 6   
107 1 Y 1 E THR 7   ? C THR 7   
108 1 Y 1 E SER 8   ? C SER 8   
109 1 Y 1 E MET 9   ? C MET 9   
110 1 Y 1 E ALA 10  ? C ALA 10  
111 1 Y 1 E ALA 11  ? C ALA 11  
112 1 Y 1 E ALA 12  ? C ALA 12  
113 1 Y 1 E SER 13  ? C SER 13  
114 1 Y 1 E THR 14  ? C THR 14  
115 1 Y 1 E VAL 15  ? C VAL 15  
116 1 Y 1 E ALA 16  ? C ALA 16  
117 1 Y 1 E PRO 17  ? C PRO 17  
118 1 Y 1 E GLU 18  ? C GLU 18  
119 1 Y 1 E VAL 19  ? C VAL 19  
120 1 Y 1 E ALA 20  ? C ALA 20  
121 1 Y 1 E MET 21  ? C MET 21  
122 1 Y 1 E ASP 22  ? C ASP 22  
123 1 Y 1 E GLU 23  ? C GLU 23  
124 1 Y 1 E GLY 24  ? C GLY 24  
125 1 Y 1 E SER 25  ? C SER 25  
126 1 Y 1 E PRO 26  ? C PRO 26  
127 1 Y 1 E SER 27  ? C SER 27  
128 1 Y 1 E THR 28  ? C THR 28  
129 1 Y 1 E SER 29  ? C SER 29  
130 1 Y 1 E GLN 30  ? C GLN 30  
131 1 Y 1 E ALA 31  ? C ALA 31  
132 1 Y 1 E GLN 32  ? C GLN 32  
133 1 Y 1 E VAL 33  ? C VAL 33  
134 1 Y 1 E GLU 34  ? C GLU 34  
135 1 Y 1 E LEU 35  ? C LEU 35  
136 1 Y 1 E PRO 36  ? C PRO 36  
137 1 Y 1 E ARG 37  ? C ARG 37  
138 1 Y 1 E ASN 38  ? C ASN 38  
139 1 Y 1 E LEU 39  ? C LEU 39  
140 1 Y 1 E GLU 40  ? C GLU 40  
141 1 Y 1 E VAL 41  ? C VAL 41  
142 1 Y 1 E PHE 42  ? C PHE 42  
143 1 Y 1 E ASN 43  ? C ASN 43  
144 1 Y 1 E GLU 44  ? C GLU 44  
145 1 Y 1 E ALA 45  ? C ALA 45  
146 1 Y 1 E CYS 46  ? C CYS 46  
147 1 Y 1 E GLY 47  ? C GLY 47  
148 1 Y 1 E HIS 48  ? C HIS 48  
149 1 Y 1 E VAL 49  ? C VAL 49  
150 1 Y 1 E PHE 50  ? C PHE 50  
151 1 Y 1 E GLY 51  ? C GLY 51  
152 1 Y 1 E SER 52  ? C SER 52  
153 1 Y 1 E SER 53  ? C SER 53  
154 1 Y 1 E PHE 54  ? C PHE 54  
155 1 Y 1 E ASN 55  ? C ASN 55  
156 1 Y 1 E ARG 56  ? C ARG 56  
157 1 Y 1 E GLU 57  ? C GLU 57  
158 1 Y 1 E ASP 58  ? C ASP 58  
159 1 Y 1 E ASN 59  ? C ASN 59  
160 1 Y 1 E SER 60  ? C SER 60  
161 1 Y 1 E VAL 61  ? C VAL 61  
162 1 Y 1 E ILE 62  ? C ILE 62  
163 1 Y 1 E SER 63  ? C SER 63  
164 1 Y 1 E ASP 64  ? C ASP 64  
165 1 Y 1 E ALA 65  ? C ALA 65  
166 1 Y 1 E ALA 66  ? C ALA 66  
167 1 Y 1 E ALA 67  ? C ALA 67  
168 1 Y 1 E PHE 68  ? C PHE 68  
169 1 Y 1 E LEU 69  ? C LEU 69  
170 1 Y 1 E PHE 70  ? C PHE 70  
171 1 Y 1 E LYS 71  ? C LYS 71  
172 1 Y 1 E MET 72  ? C MET 72  
173 1 Y 1 E HIS 73  ? C HIS 73  
174 1 Y 1 E THR 74  ? C THR 74  
175 1 Y 1 E HIS 75  ? C HIS 75  
176 1 Y 1 E SER 76  ? C SER 76  
177 1 Y 1 E LEU 77  ? C LEU 77  
178 1 Y 1 E ASP 78  ? C ASP 78  
179 1 Y 1 E GLY 79  ? C GLY 79  
180 1 Y 1 E GLN 80  ? C GLN 80  
181 1 Y 1 E GLU 81  ? C GLU 81  
182 1 Y 1 E ALA 82  ? C ALA 82  
183 1 Y 1 E LYS 83  ? C LYS 83  
184 1 Y 1 E VAL 84  ? C VAL 84  
185 1 Y 1 E LEU 85  ? C LEU 85  
186 1 Y 1 E ARG 86  ? C ARG 86  
187 1 Y 1 E ALA 87  ? C ALA 87  
188 1 Y 1 E SER 88  ? C SER 88  
189 1 Y 1 E GLU 89  ? C GLU 89  
190 1 Y 1 E LYS 90  ? C LYS 90  
191 1 Y 1 E LYS 91  ? C LYS 91  
192 1 Y 1 E ARG 92  ? C ARG 92  
193 1 Y 1 E GLU 93  ? C GLU 93  
194 1 Y 1 E ARG 94  ? C ARG 94  
195 1 Y 1 E GLU 95  ? C GLU 95  
196 1 Y 1 E ASN 96  ? C ASN 96  
197 1 Y 1 E ALA 97  ? C ALA 97  
198 1 Y 1 E LYS 98  ? C LYS 98  
199 1 Y 1 E LYS 99  ? C LYS 99  
200 1 Y 1 E SER 100 ? C SER 100 
201 1 Y 1 E ARG 101 ? C ARG 101 
202 1 Y 1 E LYS 102 ? C LYS 102 
203 1 Y 1 E ALA 103 ? C ALA 103 
204 1 Y 1 E PRO 104 ? C PRO 104 
205 1 Y 1 E GLU 105 ? C GLU 105 
206 1 Y 1 E ALA 106 ? C ALA 106 
207 1 Y 1 E GLY 107 ? C GLY 107 
208 1 Y 1 E MET 108 ? C MET 108 
209 1 Y 1 E ARG 109 ? C ARG 109 
210 1 Y 1 E VAL 110 ? C VAL 110 
211 1 Y 1 E GLY 111 ? C GLY 111 
212 1 Y 1 E ARG 112 ? C ARG 112 
213 1 Y 1 E SER 113 ? C SER 113 
214 1 Y 1 E LEU 114 ? C LEU 114 
215 1 Y 1 E ILE 115 ? C ILE 115 
216 1 Y 1 E LEU 116 ? C LEU 116 
217 1 Y 1 E THR 117 ? C THR 117 
218 1 Y 1 E SER 118 ? C SER 118 
219 1 Y 1 E ARG 119 ? C ARG 119 
220 1 Y 1 E TRP 120 ? C TRP 120 
221 1 Y 1 E THR 121 ? C THR 121 
222 1 Y 1 E GLU 122 ? C GLU 122 
223 1 Y 1 E TYR 123 ? C TYR 123 
224 1 Y 1 E CYS 124 ? C CYS 124 
225 1 Y 1 E ALA 125 ? C ALA 125 
226 1 Y 1 E THR 126 ? C THR 126 
227 1 Y 1 E CYS 127 ? C CYS 127 
228 1 Y 1 E VAL 128 ? C VAL 128 
229 1 Y 1 E PRO 129 ? C PRO 129 
230 1 Y 1 E ALA 130 ? C ALA 130 
231 1 Y 1 E LEU 131 ? C LEU 131 
232 1 Y 1 E GLY 132 ? C GLY 132 
233 1 Y 1 E SER 133 ? C SER 133 
234 1 Y 1 E LYS 134 ? C LYS 134 
235 1 Y 1 E MET 135 ? C MET 135 
236 1 Y 1 E LYS 136 ? C LYS 136 
237 1 Y 1 E VAL 137 ? C VAL 137 
238 1 Y 1 E ILE 138 ? C ILE 138 
239 1 Y 1 E LYS 139 ? C LYS 139 
240 1 Y 1 E ALA 140 ? C ALA 140 
241 1 Y 1 E SER 141 ? C SER 141 
242 1 Y 1 E GLY 142 ? C GLY 142 
243 1 Y 1 E ASP 143 ? C ASP 143 
244 1 Y 1 E ALA 144 ? C ALA 144 
245 1 Y 1 E ALA 145 ? C ALA 145 
246 1 Y 1 E MET 146 ? C MET 146 
247 1 Y 1 E ILE 147 ? C ILE 147 
248 1 Y 1 E GLN 148 ? C GLN 148 
249 1 Y 1 E MET 149 ? C MET 149 
250 1 Y 1 E MET 150 ? C MET 150 
251 1 Y 1 E LYS 151 ? C LYS 151 
252 1 Y 1 E ASP 152 ? C ASP 152 
253 1 Y 1 E HIS 153 ? C HIS 153 
254 1 Y 1 E ASN 154 ? C ASN 154 
255 1 Y 1 E SER 155 ? C SER 155 
256 1 Y 1 E LEU 156 ? C LEU 156 
257 1 Y 1 E LEU 157 ? C LEU 157 
258 1 Y 1 E ARG 158 ? C ARG 158 
259 1 Y 1 E VAL 159 ? C VAL 159 
260 1 Y 1 E CYS 160 ? C CYS 160 
261 1 Y 1 E VAL 161 ? C VAL 161 
262 1 Y 1 E ARG 162 ? C ARG 162 
263 1 Y 1 E ILE 163 ? C ILE 163 
264 1 Y 1 E GLU 164 ? C GLU 164 
265 1 Y 1 E VAL 165 ? C VAL 165 
266 1 Y 1 E TRP 166 ? C TRP 166 
267 1 Y 1 E LYS 167 ? C LYS 167 
268 1 Y 1 E ALA 168 ? C ALA 168 
269 1 Y 1 E ARG 169 ? C ARG 169 
270 1 Y 1 E TYR 170 ? C TYR 170 
271 1 Y 1 E VAL 171 ? C VAL 171 
272 1 Y 1 E SER 172 ? C SER 172 
273 1 Y 1 E LEU 173 ? C LEU 173 
274 1 Y 1 E VAL 174 ? C VAL 174 
275 1 Y 1 E ALA 175 ? C ALA 175 
276 1 Y 1 E LEU 176 ? C LEU 176 
277 1 Y 1 E ASP 177 ? C ASP 177 
278 1 Y 1 E GLU 178 ? C GLU 178 
279 1 Y 1 E ARG 179 ? C ARG 179 
280 1 Y 1 E ILE 180 ? C ILE 180 
281 1 Y 1 E GLN 181 ? C GLN 181 
282 1 Y 1 E THR 182 ? C THR 182 
283 1 Y 1 E LEU 183 ? C LEU 183 
284 1 Y 1 E GLU 184 ? C GLU 184 
285 1 Y 1 E ASP 185 ? C ASP 185 
286 1 Y 1 E ALA 186 ? C ALA 186 
287 1 Y 1 E GLN 187 ? C GLN 187 
288 1 Y 1 E TRP 188 ? C TRP 188 
289 1 Y 1 E PHE 189 ? C PHE 189 
290 1 Y 1 E PRO 190 ? C PRO 190 
291 1 Y 1 E TYR 191 ? C TYR 191 
292 1 Y 1 E LEU 192 ? C LEU 192 
293 1 Y 1 E SER 193 ? C SER 193 
294 1 Y 1 E GLY 194 ? C GLY 194 
295 1 Y 1 E ASP 195 ? C ASP 195 
296 1 Y 1 E SER 196 ? C SER 196 
297 1 Y 1 E TYR 197 ? C TYR 197 
298 1 Y 1 E ARG 198 ? C ARG 198 
299 1 Y 1 E ALA 199 ? C ALA 199 
300 1 Y 1 E CYS 200 ? C CYS 200 
301 1 Y 1 E PRO 201 ? C PRO 201 
302 1 Y 1 E GLY 202 ? C GLY 202 
303 1 Y 1 E LEU 203 ? C LEU 203 
304 1 Y 1 E VAL 204 ? C VAL 204 
305 1 Y 1 E GLY 205 ? C GLY 205 
306 1 Y 1 E GLY 206 ? C GLY 206 
307 1 Y 1 E TYR 207 ? C TYR 207 
308 1 Y 1 E PHE 208 ? C PHE 208 
309 1 Y 1 E ALA 209 ? C ALA 209 
310 1 Y 1 E LYS 210 ? C LYS 210 
311 1 Y 1 E LYS 211 ? C LYS 211 
312 1 Y 1 E ALA 212 ? C ALA 212 
313 1 Y 1 E ALA 213 ? C ALA 213 
314 1 Y 1 E ALA 214 ? C ALA 214 
315 1 Y 1 E GLY 215 ? C GLY 215 
316 1 Y 1 E GLU 216 ? C GLU 216 
317 1 Y 1 E ARG 217 ? C ARG 217 
318 1 Y 1 E GLY 218 ? C GLY 218 
319 1 Y 1 E LYS 219 ? C LYS 219 
320 1 Y 1 E ASN 220 ? C ASN 220 
321 1 Y 1 E TYR 221 ? C TYR 221 
322 1 Y 1 E LYS 222 ? C LYS 222 
323 1 Y 1 E LYS 223 ? C LYS 223 
324 1 Y 1 E LEU 224 ? C LEU 224 
325 1 Y 1 E ASN 225 ? C ASN 225 
326 1 Y 1 E GLN 226 ? C GLN 226 
327 1 Y 1 E THR 227 ? C THR 227 
328 1 Y 1 E ALA 228 ? C ALA 228 
329 1 Y 1 E ILE 229 ? C ILE 229 
330 1 Y 1 E ILE 230 ? C ILE 230 
331 1 Y 1 E PRO 231 ? C PRO 231 
332 1 Y 1 E PRO 232 ? C PRO 232 
333 1 Y 1 E PRO 233 ? C PRO 233 
334 1 Y 1 E ARG 234 ? C ARG 234 
335 1 Y 1 E PHE 235 ? C PHE 235 
336 1 Y 1 E LEU 236 ? C LEU 236 
337 1 Y 1 E ILE 237 ? C ILE 237 
338 1 Y 1 E ILE 238 ? C ILE 238 
339 1 Y 1 E GLY 239 ? C GLY 239 
340 1 Y 1 E HIS 240 ? C HIS 240 
341 1 Y 1 E ARG 241 ? C ARG 241 
342 1 Y 1 E LEU 242 ? C LEU 242 
343 1 Y 1 E GLN 243 ? C GLN 243 
344 1 Y 1 E ILE 244 ? C ILE 244 
345 1 Y 1 E GLY 245 ? C GLY 245 
346 1 Y 1 E ASP 246 ? C ASP 246 
347 1 Y 1 E GLN 247 ? C GLN 247 
348 1 Y 1 E VAL 248 ? C VAL 248 
349 1 Y 1 E THR 249 ? C THR 249 
350 1 Y 1 E LEU 250 ? C LEU 250 
351 1 Y 1 E ARG 251 ? C ARG 251 
352 1 Y 1 E GLU 252 ? C GLU 252 
353 1 Y 1 E LEU 253 ? C LEU 253 
354 1 Y 1 E LEU 254 ? C LEU 254 
355 1 Y 1 E ALA 255 ? C ALA 255 
356 1 Y 1 E SER 256 ? C SER 256 
357 1 Y 1 E ILE 257 ? C ILE 257 
358 1 Y 1 E ALA 258 ? C ALA 258 
359 1 Y 1 E TRP 259 ? C TRP 259 
360 1 Y 1 E GLY 260 ? C GLY 260 
361 1 Y 1 E LEU 261 ? C LEU 261 
362 1 Y 1 E CYS 262 ? C CYS 262 
363 1 Y 1 E ASP 263 ? C ASP 263 
364 1 Y 1 E GLY 264 ? C GLY 264 
365 1 Y 1 E VAL 265 ? C VAL 265 
366 1 Y 1 E LEU 266 ? C LEU 266 
367 1 Y 1 E ALA 267 ? C ALA 267 
368 1 Y 1 E GLU 268 ? C GLU 268 
369 1 Y 1 E CYS 269 ? C CYS 269 
370 1 Y 1 E TRP 270 ? C TRP 270 
371 1 Y 1 E SER 271 ? C SER 271 
372 1 Y 1 E PRO 272 ? C PRO 272 
373 1 Y 1 E SER 273 ? C SER 273 
374 1 Y 1 E GLN 274 ? C GLN 274 
375 1 Y 1 E GLY 275 ? C GLY 275 
376 1 Y 1 E ASP 276 ? C ASP 276 
377 1 Y 1 E GLY 277 ? C GLY 277 
378 1 Y 1 E SER 278 ? C SER 278 
379 1 Y 1 E ILE 279 ? C ILE 279 
380 1 Y 1 E GLY 280 ? C GLY 280 
381 1 Y 1 E VAL 281 ? C VAL 281 
382 1 Y 1 E VAL 282 ? C VAL 282 
383 1 Y 1 E VAL 283 ? C VAL 283 
384 1 Y 1 E GLY 284 ? C GLY 284 
385 1 Y 1 E LEU 285 ? C LEU 285 
386 1 Y 1 E PRO 286 ? C PRO 286 
387 1 Y 1 E LEU 287 ? C LEU 287 
388 1 Y 1 E GLN 288 ? C GLN 288 
389 1 Y 1 E ALA 289 ? C ALA 289 
390 1 Y 1 E THR 290 ? C THR 290 
391 1 Y 1 E GLY 312 ? C GLY 312 
392 1 Y 1 E THR 313 ? C THR 313 
393 1 Y 1 E GLY 314 ? C GLY 314 
394 1 Y 1 E ASN 315 ? C ASN 315 
395 1 Y 1 E THR 316 ? C THR 316 
396 1 Y 1 E ASN 317 ? C ASN 317 
397 1 Y 1 E LEU 318 ? C LEU 318 
398 1 Y 1 E LEU 319 ? C LEU 319 
399 1 Y 1 E GLU 320 ? C GLU 320 
400 1 Y 1 E GLU 321 ? C GLU 321 
401 1 Y 1 E CYS 322 ? C CYS 322 
402 1 Y 1 E ILE 323 ? C ILE 323 
403 1 Y 1 E ALA 324 ? C ALA 324 
404 1 Y 1 E ILE 325 ? C ILE 325 
405 1 Y 1 E GLN 326 ? C GLN 326 
406 1 Y 1 E LYS 327 ? C LYS 327 
407 1 Y 1 E GLN 328 ? C GLN 328 
408 1 Y 1 E ASP 329 ? C ASP 329 
409 1 Y 1 E GLY 330 ? C GLY 330 
410 1 Y 1 E VAL 331 ? C VAL 331 
411 1 Y 1 E ILE 332 ? C ILE 332 
412 1 Y 1 E LYS 333 ? C LYS 333 
413 1 Y 1 E CYS 334 ? C CYS 334 
414 1 Y 1 E LYS 335 ? C LYS 335 
415 1 Y 1 E ARG 336 ? C ARG 336 
416 1 Y 1 E SER 337 ? C SER 337 
417 1 Y 1 E GLY 338 ? C GLY 338 
418 1 Y 1 E LYS 339 ? C LYS 339 
419 1 Y 1 E SER 340 ? C SER 340 
420 1 Y 1 E LEU 341 ? C LEU 341 
421 1 Y 1 E TYR 342 ? C TYR 342 
422 1 Y 1 E HIS 343 ? C HIS 343 
423 1 Y 1 E CYS 344 ? C CYS 344 
424 1 Y 1 E LEU 345 ? C LEU 345 
425 1 Y 1 E LYS 346 ? C LYS 346 
426 1 Y 1 E GLU 347 ? C GLU 347 
427 1 Y 1 E THR 348 ? C THR 348 
428 1 Y 1 E ALA 349 ? C ALA 349 
429 1 Y 1 E GLY 350 ? C GLY 350 
430 1 Y 1 E ALA 351 ? C ALA 351 
431 1 Y 1 E VAL 352 ? C VAL 352 
432 1 Y 1 E GLY 353 ? C GLY 353 
433 1 Y 1 E ARG 354 ? C ARG 354 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
ARG N      N N N 14  
ARG CA     C N S 15  
ARG C      C N N 16  
ARG O      O N N 17  
ARG CB     C N N 18  
ARG CG     C N N 19  
ARG CD     C N N 20  
ARG NE     N N N 21  
ARG CZ     C N N 22  
ARG NH1    N N N 23  
ARG NH2    N N N 24  
ARG OXT    O N N 25  
ARG H      H N N 26  
ARG H2     H N N 27  
ARG HA     H N N 28  
ARG HB2    H N N 29  
ARG HB3    H N N 30  
ARG HG2    H N N 31  
ARG HG3    H N N 32  
ARG HD2    H N N 33  
ARG HD3    H N N 34  
ARG HE     H N N 35  
ARG HH11   H N N 36  
ARG HH12   H N N 37  
ARG HH21   H N N 38  
ARG HH22   H N N 39  
ARG HXT    H N N 40  
ASN N      N N N 41  
ASN CA     C N S 42  
ASN C      C N N 43  
ASN O      O N N 44  
ASN CB     C N N 45  
ASN CG     C N N 46  
ASN OD1    O N N 47  
ASN ND2    N N N 48  
ASN OXT    O N N 49  
ASN H      H N N 50  
ASN H2     H N N 51  
ASN HA     H N N 52  
ASN HB2    H N N 53  
ASN HB3    H N N 54  
ASN HD21   H N N 55  
ASN HD22   H N N 56  
ASN HXT    H N N 57  
ASP N      N N N 58  
ASP CA     C N S 59  
ASP C      C N N 60  
ASP O      O N N 61  
ASP CB     C N N 62  
ASP CG     C N N 63  
ASP OD1    O N N 64  
ASP OD2    O N N 65  
ASP OXT    O N N 66  
ASP H      H N N 67  
ASP H2     H N N 68  
ASP HA     H N N 69  
ASP HB2    H N N 70  
ASP HB3    H N N 71  
ASP HD2    H N N 72  
ASP HXT    H N N 73  
CYS N      N N N 74  
CYS CA     C N R 75  
CYS C      C N N 76  
CYS O      O N N 77  
CYS CB     C N N 78  
CYS SG     S N N 79  
CYS OXT    O N N 80  
CYS H      H N N 81  
CYS H2     H N N 82  
CYS HA     H N N 83  
CYS HB2    H N N 84  
CYS HB3    H N N 85  
CYS HG     H N N 86  
CYS HXT    H N N 87  
GLN N      N N N 88  
GLN CA     C N S 89  
GLN C      C N N 90  
GLN O      O N N 91  
GLN CB     C N N 92  
GLN CG     C N N 93  
GLN CD     C N N 94  
GLN OE1    O N N 95  
GLN NE2    N N N 96  
GLN OXT    O N N 97  
GLN H      H N N 98  
GLN H2     H N N 99  
GLN HA     H N N 100 
GLN HB2    H N N 101 
GLN HB3    H N N 102 
GLN HG2    H N N 103 
GLN HG3    H N N 104 
GLN HE21   H N N 105 
GLN HE22   H N N 106 
GLN HXT    H N N 107 
GLU N      N N N 108 
GLU CA     C N S 109 
GLU C      C N N 110 
GLU O      O N N 111 
GLU CB     C N N 112 
GLU CG     C N N 113 
GLU CD     C N N 114 
GLU OE1    O N N 115 
GLU OE2    O N N 116 
GLU OXT    O N N 117 
GLU H      H N N 118 
GLU H2     H N N 119 
GLU HA     H N N 120 
GLU HB2    H N N 121 
GLU HB3    H N N 122 
GLU HG2    H N N 123 
GLU HG3    H N N 124 
GLU HE2    H N N 125 
GLU HXT    H N N 126 
GLY N      N N N 127 
GLY CA     C N N 128 
GLY C      C N N 129 
GLY O      O N N 130 
GLY OXT    O N N 131 
GLY H      H N N 132 
GLY H2     H N N 133 
GLY HA2    H N N 134 
GLY HA3    H N N 135 
GLY HXT    H N N 136 
HIS N      N N N 137 
HIS CA     C N S 138 
HIS C      C N N 139 
HIS O      O N N 140 
HIS CB     C N N 141 
HIS CG     C Y N 142 
HIS ND1    N Y N 143 
HIS CD2    C Y N 144 
HIS CE1    C Y N 145 
HIS NE2    N Y N 146 
HIS OXT    O N N 147 
HIS H      H N N 148 
HIS H2     H N N 149 
HIS HA     H N N 150 
HIS HB2    H N N 151 
HIS HB3    H N N 152 
HIS HD1    H N N 153 
HIS HD2    H N N 154 
HIS HE1    H N N 155 
HIS HE2    H N N 156 
HIS HXT    H N N 157 
ILE N      N N N 158 
ILE CA     C N S 159 
ILE C      C N N 160 
ILE O      O N N 161 
ILE CB     C N S 162 
ILE CG1    C N N 163 
ILE CG2    C N N 164 
ILE CD1    C N N 165 
ILE OXT    O N N 166 
ILE H      H N N 167 
ILE H2     H N N 168 
ILE HA     H N N 169 
ILE HB     H N N 170 
ILE HG12   H N N 171 
ILE HG13   H N N 172 
ILE HG21   H N N 173 
ILE HG22   H N N 174 
ILE HG23   H N N 175 
ILE HD11   H N N 176 
ILE HD12   H N N 177 
ILE HD13   H N N 178 
ILE HXT    H N N 179 
LEU N      N N N 180 
LEU CA     C N S 181 
LEU C      C N N 182 
LEU O      O N N 183 
LEU CB     C N N 184 
LEU CG     C N N 185 
LEU CD1    C N N 186 
LEU CD2    C N N 187 
LEU OXT    O N N 188 
LEU H      H N N 189 
LEU H2     H N N 190 
LEU HA     H N N 191 
LEU HB2    H N N 192 
LEU HB3    H N N 193 
LEU HG     H N N 194 
LEU HD11   H N N 195 
LEU HD12   H N N 196 
LEU HD13   H N N 197 
LEU HD21   H N N 198 
LEU HD22   H N N 199 
LEU HD23   H N N 200 
LEU HXT    H N N 201 
LYS N      N N N 202 
LYS CA     C N S 203 
LYS C      C N N 204 
LYS O      O N N 205 
LYS CB     C N N 206 
LYS CG     C N N 207 
LYS CD     C N N 208 
LYS CE     C N N 209 
LYS NZ     N N N 210 
LYS OXT    O N N 211 
LYS H      H N N 212 
LYS H2     H N N 213 
LYS HA     H N N 214 
LYS HB2    H N N 215 
LYS HB3    H N N 216 
LYS HG2    H N N 217 
LYS HG3    H N N 218 
LYS HD2    H N N 219 
LYS HD3    H N N 220 
LYS HE2    H N N 221 
LYS HE3    H N N 222 
LYS HZ1    H N N 223 
LYS HZ2    H N N 224 
LYS HZ3    H N N 225 
LYS HXT    H N N 226 
MET N      N N N 227 
MET CA     C N S 228 
MET C      C N N 229 
MET O      O N N 230 
MET CB     C N N 231 
MET CG     C N N 232 
MET SD     S N N 233 
MET CE     C N N 234 
MET OXT    O N N 235 
MET H      H N N 236 
MET H2     H N N 237 
MET HA     H N N 238 
MET HB2    H N N 239 
MET HB3    H N N 240 
MET HG2    H N N 241 
MET HG3    H N N 242 
MET HE1    H N N 243 
MET HE2    H N N 244 
MET HE3    H N N 245 
MET HXT    H N N 246 
P5P N1     N Y N 247 
P5P C2     C Y N 248 
P5P N3     N Y N 249 
P5P C4     C Y N 250 
P5P C5     C Y N 251 
P5P C6     C Y N 252 
P5P N7     N Y N 253 
P5P C8     C Y N 254 
P5P N9     N Y N 255 
P5P "C1'"  C N R 256 
P5P "C2'"  C N R 257 
P5P "O2'"  O N N 258 
P5P "C3'"  C N S 259 
P5P "O3'"  O N N 260 
P5P "C4'"  C N R 261 
P5P "O4'"  O N N 262 
P5P "C5'"  C N N 263 
P5P "O5'"  O N N 264 
P5P P      P N N 265 
P5P OP1    O N N 266 
P5P OP2    O N N 267 
P5P OP3    O N N 268 
P5P H2     H N N 269 
P5P H6     H N N 270 
P5P H8     H N N 271 
P5P "H1'"  H N N 272 
P5P "H2'"  H N N 273 
P5P "HO2'" H N N 274 
P5P "H3'"  H N N 275 
P5P "HO3'" H N N 276 
P5P "H4'"  H N N 277 
P5P "H5'1" H N N 278 
P5P "H5'2" H N N 279 
P5P HOP2   H N N 280 
P5P HOP3   H N N 281 
PHE N      N N N 282 
PHE CA     C N S 283 
PHE C      C N N 284 
PHE O      O N N 285 
PHE CB     C N N 286 
PHE CG     C Y N 287 
PHE CD1    C Y N 288 
PHE CD2    C Y N 289 
PHE CE1    C Y N 290 
PHE CE2    C Y N 291 
PHE CZ     C Y N 292 
PHE OXT    O N N 293 
PHE H      H N N 294 
PHE H2     H N N 295 
PHE HA     H N N 296 
PHE HB2    H N N 297 
PHE HB3    H N N 298 
PHE HD1    H N N 299 
PHE HD2    H N N 300 
PHE HE1    H N N 301 
PHE HE2    H N N 302 
PHE HZ     H N N 303 
PHE HXT    H N N 304 
PRO N      N N N 305 
PRO CA     C N S 306 
PRO C      C N N 307 
PRO O      O N N 308 
PRO CB     C N N 309 
PRO CG     C N N 310 
PRO CD     C N N 311 
PRO OXT    O N N 312 
PRO H      H N N 313 
PRO HA     H N N 314 
PRO HB2    H N N 315 
PRO HB3    H N N 316 
PRO HG2    H N N 317 
PRO HG3    H N N 318 
PRO HD2    H N N 319 
PRO HD3    H N N 320 
PRO HXT    H N N 321 
SER N      N N N 322 
SER CA     C N S 323 
SER C      C N N 324 
SER O      O N N 325 
SER CB     C N N 326 
SER OG     O N N 327 
SER OXT    O N N 328 
SER H      H N N 329 
SER H2     H N N 330 
SER HA     H N N 331 
SER HB2    H N N 332 
SER HB3    H N N 333 
SER HG     H N N 334 
SER HXT    H N N 335 
THR N      N N N 336 
THR CA     C N S 337 
THR C      C N N 338 
THR O      O N N 339 
THR CB     C N R 340 
THR OG1    O N N 341 
THR CG2    C N N 342 
THR OXT    O N N 343 
THR H      H N N 344 
THR H2     H N N 345 
THR HA     H N N 346 
THR HB     H N N 347 
THR HG1    H N N 348 
THR HG21   H N N 349 
THR HG22   H N N 350 
THR HG23   H N N 351 
THR HXT    H N N 352 
TRP N      N N N 353 
TRP CA     C N S 354 
TRP C      C N N 355 
TRP O      O N N 356 
TRP CB     C N N 357 
TRP CG     C Y N 358 
TRP CD1    C Y N 359 
TRP CD2    C Y N 360 
TRP NE1    N Y N 361 
TRP CE2    C Y N 362 
TRP CE3    C Y N 363 
TRP CZ2    C Y N 364 
TRP CZ3    C Y N 365 
TRP CH2    C Y N 366 
TRP OXT    O N N 367 
TRP H      H N N 368 
TRP H2     H N N 369 
TRP HA     H N N 370 
TRP HB2    H N N 371 
TRP HB3    H N N 372 
TRP HD1    H N N 373 
TRP HE1    H N N 374 
TRP HE3    H N N 375 
TRP HZ2    H N N 376 
TRP HZ3    H N N 377 
TRP HH2    H N N 378 
TRP HXT    H N N 379 
TYR N      N N N 380 
TYR CA     C N S 381 
TYR C      C N N 382 
TYR O      O N N 383 
TYR CB     C N N 384 
TYR CG     C Y N 385 
TYR CD1    C Y N 386 
TYR CD2    C Y N 387 
TYR CE1    C Y N 388 
TYR CE2    C Y N 389 
TYR CZ     C Y N 390 
TYR OH     O N N 391 
TYR OXT    O N N 392 
TYR H      H N N 393 
TYR H2     H N N 394 
TYR HA     H N N 395 
TYR HB2    H N N 396 
TYR HB3    H N N 397 
TYR HD1    H N N 398 
TYR HD2    H N N 399 
TYR HE1    H N N 400 
TYR HE2    H N N 401 
TYR HH     H N N 402 
TYR HXT    H N N 403 
VAL N      N N N 404 
VAL CA     C N S 405 
VAL C      C N N 406 
VAL O      O N N 407 
VAL CB     C N N 408 
VAL CG1    C N N 409 
VAL CG2    C N N 410 
VAL OXT    O N N 411 
VAL H      H N N 412 
VAL H2     H N N 413 
VAL HA     H N N 414 
VAL HB     H N N 415 
VAL HG11   H N N 416 
VAL HG12   H N N 417 
VAL HG13   H N N 418 
VAL HG21   H N N 419 
VAL HG22   H N N 420 
VAL HG23   H N N 421 
VAL HXT    H N N 422 
Y5P OP3    O N N 423 
Y5P P      P N N 424 
Y5P "C5'"  C N N 425 
Y5P "O5'"  O N N 426 
Y5P "C4'"  C N R 427 
Y5P "O4'"  O N N 428 
Y5P "C3'"  C N S 429 
Y5P "O3'"  O N N 430 
Y5P "C2'"  C N R 431 
Y5P "O2'"  O N N 432 
Y5P "C1'"  C N R 433 
Y5P N1     N N N 434 
Y5P C2     C N N 435 
Y5P N3     N N N 436 
Y5P C4     C N N 437 
Y5P C6     C N N 438 
Y5P OP1    O N N 439 
Y5P OP2    O N N 440 
Y5P C5     C N N 441 
Y5P HP3    H N N 442 
Y5P HP2    H N N 443 
Y5P HA1    H N N 444 
Y5P HB2    H N N 445 
Y5P HA     H N N 446 
Y5P HB     H N N 447 
Y5P HC     H N N 448 
Y5P "H2'"  H N N 449 
Y5P HD     H N N 450 
Y5P H2     H N N 451 
Y5P H6     H N N 452 
Y5P H4     H N N 453 
Y5P H5     H N N 454 
Y5P H4A    H N N 455 
Y5P "H3'"  H N N 456 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
GLN N     CA     sing N N 83  
GLN N     H      sing N N 84  
GLN N     H2     sing N N 85  
GLN CA    C      sing N N 86  
GLN CA    CB     sing N N 87  
GLN CA    HA     sing N N 88  
GLN C     O      doub N N 89  
GLN C     OXT    sing N N 90  
GLN CB    CG     sing N N 91  
GLN CB    HB2    sing N N 92  
GLN CB    HB3    sing N N 93  
GLN CG    CD     sing N N 94  
GLN CG    HG2    sing N N 95  
GLN CG    HG3    sing N N 96  
GLN CD    OE1    doub N N 97  
GLN CD    NE2    sing N N 98  
GLN NE2   HE21   sing N N 99  
GLN NE2   HE22   sing N N 100 
GLN OXT   HXT    sing N N 101 
GLU N     CA     sing N N 102 
GLU N     H      sing N N 103 
GLU N     H2     sing N N 104 
GLU CA    C      sing N N 105 
GLU CA    CB     sing N N 106 
GLU CA    HA     sing N N 107 
GLU C     O      doub N N 108 
GLU C     OXT    sing N N 109 
GLU CB    CG     sing N N 110 
GLU CB    HB2    sing N N 111 
GLU CB    HB3    sing N N 112 
GLU CG    CD     sing N N 113 
GLU CG    HG2    sing N N 114 
GLU CG    HG3    sing N N 115 
GLU CD    OE1    doub N N 116 
GLU CD    OE2    sing N N 117 
GLU OE2   HE2    sing N N 118 
GLU OXT   HXT    sing N N 119 
GLY N     CA     sing N N 120 
GLY N     H      sing N N 121 
GLY N     H2     sing N N 122 
GLY CA    C      sing N N 123 
GLY CA    HA2    sing N N 124 
GLY CA    HA3    sing N N 125 
GLY C     O      doub N N 126 
GLY C     OXT    sing N N 127 
GLY OXT   HXT    sing N N 128 
HIS N     CA     sing N N 129 
HIS N     H      sing N N 130 
HIS N     H2     sing N N 131 
HIS CA    C      sing N N 132 
HIS CA    CB     sing N N 133 
HIS CA    HA     sing N N 134 
HIS C     O      doub N N 135 
HIS C     OXT    sing N N 136 
HIS CB    CG     sing N N 137 
HIS CB    HB2    sing N N 138 
HIS CB    HB3    sing N N 139 
HIS CG    ND1    sing Y N 140 
HIS CG    CD2    doub Y N 141 
HIS ND1   CE1    doub Y N 142 
HIS ND1   HD1    sing N N 143 
HIS CD2   NE2    sing Y N 144 
HIS CD2   HD2    sing N N 145 
HIS CE1   NE2    sing Y N 146 
HIS CE1   HE1    sing N N 147 
HIS NE2   HE2    sing N N 148 
HIS OXT   HXT    sing N N 149 
ILE N     CA     sing N N 150 
ILE N     H      sing N N 151 
ILE N     H2     sing N N 152 
ILE CA    C      sing N N 153 
ILE CA    CB     sing N N 154 
ILE CA    HA     sing N N 155 
ILE C     O      doub N N 156 
ILE C     OXT    sing N N 157 
ILE CB    CG1    sing N N 158 
ILE CB    CG2    sing N N 159 
ILE CB    HB     sing N N 160 
ILE CG1   CD1    sing N N 161 
ILE CG1   HG12   sing N N 162 
ILE CG1   HG13   sing N N 163 
ILE CG2   HG21   sing N N 164 
ILE CG2   HG22   sing N N 165 
ILE CG2   HG23   sing N N 166 
ILE CD1   HD11   sing N N 167 
ILE CD1   HD12   sing N N 168 
ILE CD1   HD13   sing N N 169 
ILE OXT   HXT    sing N N 170 
LEU N     CA     sing N N 171 
LEU N     H      sing N N 172 
LEU N     H2     sing N N 173 
LEU CA    C      sing N N 174 
LEU CA    CB     sing N N 175 
LEU CA    HA     sing N N 176 
LEU C     O      doub N N 177 
LEU C     OXT    sing N N 178 
LEU CB    CG     sing N N 179 
LEU CB    HB2    sing N N 180 
LEU CB    HB3    sing N N 181 
LEU CG    CD1    sing N N 182 
LEU CG    CD2    sing N N 183 
LEU CG    HG     sing N N 184 
LEU CD1   HD11   sing N N 185 
LEU CD1   HD12   sing N N 186 
LEU CD1   HD13   sing N N 187 
LEU CD2   HD21   sing N N 188 
LEU CD2   HD22   sing N N 189 
LEU CD2   HD23   sing N N 190 
LEU OXT   HXT    sing N N 191 
LYS N     CA     sing N N 192 
LYS N     H      sing N N 193 
LYS N     H2     sing N N 194 
LYS CA    C      sing N N 195 
LYS CA    CB     sing N N 196 
LYS CA    HA     sing N N 197 
LYS C     O      doub N N 198 
LYS C     OXT    sing N N 199 
LYS CB    CG     sing N N 200 
LYS CB    HB2    sing N N 201 
LYS CB    HB3    sing N N 202 
LYS CG    CD     sing N N 203 
LYS CG    HG2    sing N N 204 
LYS CG    HG3    sing N N 205 
LYS CD    CE     sing N N 206 
LYS CD    HD2    sing N N 207 
LYS CD    HD3    sing N N 208 
LYS CE    NZ     sing N N 209 
LYS CE    HE2    sing N N 210 
LYS CE    HE3    sing N N 211 
LYS NZ    HZ1    sing N N 212 
LYS NZ    HZ2    sing N N 213 
LYS NZ    HZ3    sing N N 214 
LYS OXT   HXT    sing N N 215 
MET N     CA     sing N N 216 
MET N     H      sing N N 217 
MET N     H2     sing N N 218 
MET CA    C      sing N N 219 
MET CA    CB     sing N N 220 
MET CA    HA     sing N N 221 
MET C     O      doub N N 222 
MET C     OXT    sing N N 223 
MET CB    CG     sing N N 224 
MET CB    HB2    sing N N 225 
MET CB    HB3    sing N N 226 
MET CG    SD     sing N N 227 
MET CG    HG2    sing N N 228 
MET CG    HG3    sing N N 229 
MET SD    CE     sing N N 230 
MET CE    HE1    sing N N 231 
MET CE    HE2    sing N N 232 
MET CE    HE3    sing N N 233 
MET OXT   HXT    sing N N 234 
P5P N1    C2     sing Y N 235 
P5P N1    C6     doub Y N 236 
P5P C2    N3     doub Y N 237 
P5P C2    H2     sing N N 238 
P5P N3    C4     sing Y N 239 
P5P C4    C5     doub Y N 240 
P5P C4    N9     sing Y N 241 
P5P C5    C6     sing Y N 242 
P5P C5    N7     sing Y N 243 
P5P C6    H6     sing N N 244 
P5P N7    C8     doub Y N 245 
P5P C8    N9     sing Y N 246 
P5P C8    H8     sing N N 247 
P5P N9    "C1'"  sing N N 248 
P5P "C1'" "C2'"  sing N N 249 
P5P "C1'" "O4'"  sing N N 250 
P5P "C1'" "H1'"  sing N N 251 
P5P "C2'" "O2'"  sing N N 252 
P5P "C2'" "C3'"  sing N N 253 
P5P "C2'" "H2'"  sing N N 254 
P5P "O2'" "HO2'" sing N N 255 
P5P "C3'" "O3'"  sing N N 256 
P5P "C3'" "C4'"  sing N N 257 
P5P "C3'" "H3'"  sing N N 258 
P5P "O3'" "HO3'" sing N N 259 
P5P "C4'" "O4'"  sing N N 260 
P5P "C4'" "C5'"  sing N N 261 
P5P "C4'" "H4'"  sing N N 262 
P5P "C5'" "O5'"  sing N N 263 
P5P "C5'" "H5'1" sing N N 264 
P5P "C5'" "H5'2" sing N N 265 
P5P "O5'" P      sing N N 266 
P5P P     OP1    doub N N 267 
P5P P     OP2    sing N N 268 
P5P P     OP3    sing N N 269 
P5P OP2   HOP2   sing N N 270 
P5P OP3   HOP3   sing N N 271 
PHE N     CA     sing N N 272 
PHE N     H      sing N N 273 
PHE N     H2     sing N N 274 
PHE CA    C      sing N N 275 
PHE CA    CB     sing N N 276 
PHE CA    HA     sing N N 277 
PHE C     O      doub N N 278 
PHE C     OXT    sing N N 279 
PHE CB    CG     sing N N 280 
PHE CB    HB2    sing N N 281 
PHE CB    HB3    sing N N 282 
PHE CG    CD1    doub Y N 283 
PHE CG    CD2    sing Y N 284 
PHE CD1   CE1    sing Y N 285 
PHE CD1   HD1    sing N N 286 
PHE CD2   CE2    doub Y N 287 
PHE CD2   HD2    sing N N 288 
PHE CE1   CZ     doub Y N 289 
PHE CE1   HE1    sing N N 290 
PHE CE2   CZ     sing Y N 291 
PHE CE2   HE2    sing N N 292 
PHE CZ    HZ     sing N N 293 
PHE OXT   HXT    sing N N 294 
PRO N     CA     sing N N 295 
PRO N     CD     sing N N 296 
PRO N     H      sing N N 297 
PRO CA    C      sing N N 298 
PRO CA    CB     sing N N 299 
PRO CA    HA     sing N N 300 
PRO C     O      doub N N 301 
PRO C     OXT    sing N N 302 
PRO CB    CG     sing N N 303 
PRO CB    HB2    sing N N 304 
PRO CB    HB3    sing N N 305 
PRO CG    CD     sing N N 306 
PRO CG    HG2    sing N N 307 
PRO CG    HG3    sing N N 308 
PRO CD    HD2    sing N N 309 
PRO CD    HD3    sing N N 310 
PRO OXT   HXT    sing N N 311 
SER N     CA     sing N N 312 
SER N     H      sing N N 313 
SER N     H2     sing N N 314 
SER CA    C      sing N N 315 
SER CA    CB     sing N N 316 
SER CA    HA     sing N N 317 
SER C     O      doub N N 318 
SER C     OXT    sing N N 319 
SER CB    OG     sing N N 320 
SER CB    HB2    sing N N 321 
SER CB    HB3    sing N N 322 
SER OG    HG     sing N N 323 
SER OXT   HXT    sing N N 324 
THR N     CA     sing N N 325 
THR N     H      sing N N 326 
THR N     H2     sing N N 327 
THR CA    C      sing N N 328 
THR CA    CB     sing N N 329 
THR CA    HA     sing N N 330 
THR C     O      doub N N 331 
THR C     OXT    sing N N 332 
THR CB    OG1    sing N N 333 
THR CB    CG2    sing N N 334 
THR CB    HB     sing N N 335 
THR OG1   HG1    sing N N 336 
THR CG2   HG21   sing N N 337 
THR CG2   HG22   sing N N 338 
THR CG2   HG23   sing N N 339 
THR OXT   HXT    sing N N 340 
TRP N     CA     sing N N 341 
TRP N     H      sing N N 342 
TRP N     H2     sing N N 343 
TRP CA    C      sing N N 344 
TRP CA    CB     sing N N 345 
TRP CA    HA     sing N N 346 
TRP C     O      doub N N 347 
TRP C     OXT    sing N N 348 
TRP CB    CG     sing N N 349 
TRP CB    HB2    sing N N 350 
TRP CB    HB3    sing N N 351 
TRP CG    CD1    doub Y N 352 
TRP CG    CD2    sing Y N 353 
TRP CD1   NE1    sing Y N 354 
TRP CD1   HD1    sing N N 355 
TRP CD2   CE2    doub Y N 356 
TRP CD2   CE3    sing Y N 357 
TRP NE1   CE2    sing Y N 358 
TRP NE1   HE1    sing N N 359 
TRP CE2   CZ2    sing Y N 360 
TRP CE3   CZ3    doub Y N 361 
TRP CE3   HE3    sing N N 362 
TRP CZ2   CH2    doub Y N 363 
TRP CZ2   HZ2    sing N N 364 
TRP CZ3   CH2    sing Y N 365 
TRP CZ3   HZ3    sing N N 366 
TRP CH2   HH2    sing N N 367 
TRP OXT   HXT    sing N N 368 
TYR N     CA     sing N N 369 
TYR N     H      sing N N 370 
TYR N     H2     sing N N 371 
TYR CA    C      sing N N 372 
TYR CA    CB     sing N N 373 
TYR CA    HA     sing N N 374 
TYR C     O      doub N N 375 
TYR C     OXT    sing N N 376 
TYR CB    CG     sing N N 377 
TYR CB    HB2    sing N N 378 
TYR CB    HB3    sing N N 379 
TYR CG    CD1    doub Y N 380 
TYR CG    CD2    sing Y N 381 
TYR CD1   CE1    sing Y N 382 
TYR CD1   HD1    sing N N 383 
TYR CD2   CE2    doub Y N 384 
TYR CD2   HD2    sing N N 385 
TYR CE1   CZ     doub Y N 386 
TYR CE1   HE1    sing N N 387 
TYR CE2   CZ     sing Y N 388 
TYR CE2   HE2    sing N N 389 
TYR CZ    OH     sing N N 390 
TYR OH    HH     sing N N 391 
TYR OXT   HXT    sing N N 392 
VAL N     CA     sing N N 393 
VAL N     H      sing N N 394 
VAL N     H2     sing N N 395 
VAL CA    C      sing N N 396 
VAL CA    CB     sing N N 397 
VAL CA    HA     sing N N 398 
VAL C     O      doub N N 399 
VAL C     OXT    sing N N 400 
VAL CB    CG1    sing N N 401 
VAL CB    CG2    sing N N 402 
VAL CB    HB     sing N N 403 
VAL CG1   HG11   sing N N 404 
VAL CG1   HG12   sing N N 405 
VAL CG1   HG13   sing N N 406 
VAL CG2   HG21   sing N N 407 
VAL CG2   HG22   sing N N 408 
VAL CG2   HG23   sing N N 409 
VAL OXT   HXT    sing N N 410 
Y5P OP3   P      sing N N 411 
Y5P P     "O5'"  sing N N 412 
Y5P P     OP1    doub N N 413 
Y5P P     OP2    sing N N 414 
Y5P "C5'" "O5'"  sing N N 415 
Y5P "C5'" "C4'"  sing N N 416 
Y5P "C4'" "O4'"  sing N N 417 
Y5P "C4'" "C3'"  sing N N 418 
Y5P "O4'" "C1'"  sing N N 419 
Y5P "C3'" "O3'"  sing N N 420 
Y5P "C3'" "C2'"  sing N N 421 
Y5P "C2'" "O2'"  sing N N 422 
Y5P "C2'" "C1'"  sing N N 423 
Y5P "C1'" N1     sing N N 424 
Y5P N1    C2     sing N N 425 
Y5P N1    C6     sing N N 426 
Y5P C5    C6     doub N N 427 
Y5P C2    N3     doub N N 428 
Y5P N3    C4     sing N N 429 
Y5P C4    C5     sing N N 430 
Y5P OP3   HP3    sing N N 431 
Y5P OP2   HP2    sing N N 432 
Y5P "C5'" HA1    sing N N 433 
Y5P "C5'" HB2    sing N N 434 
Y5P "C4'" HA     sing N N 435 
Y5P "C3'" HB     sing N N 436 
Y5P "C1'" HC     sing N N 437 
Y5P "C2'" "H2'"  sing N N 438 
Y5P "O2'" HD     sing N N 439 
Y5P C2    H2     sing N N 440 
Y5P C6    H6     sing N N 441 
Y5P C4    H4     sing N N 442 
Y5P "O3'" "H3'"  sing N N 443 
Y5P H5    C5     sing N N 444 
Y5P C4    H4A    sing N N 445 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-11-08 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9HBV 
_em_admin.last_update        2025-03-12 
_em_admin.map_release_date   2025-03-12 
_em_admin.title              'TiLV-NP tetramer (pseudo-C4) (local refinement around 2 TiLV-NPs)' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          1549864 
_em_entity_assembly_naturalsource.organism             'Tilapia lake virus' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7111 
_em_entity_assembly_recombinant.organism             'Trichoplusia ni' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         40 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? cryoSPARC      ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ?              ? 
MASKING                    ? 3  ? ? ? ?              ? 
'CTF CORRECTION'           ? 4  1 ? ? cryoSPARC      ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ?              ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?              ? 
'MODEL FITTING'            ? 7  ? 1 ? 'UCSF Chimera' ? 
OTHER                      ? 8  ? ? ? ?              ? 
'MODEL REFINEMENT'         ? 9  ? 1 ? PHENIX         ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? cryoSPARC      ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? cryoSPARC      ? 
CLASSIFICATION             ? 12 1 ? ? cryoSPARC      ? 
RECONSTRUCTION             ? 13 1 ? ? cryoSPARC      ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Other government' 
_pdbx_audit_support.country                France 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   ? 
# 
_atom_sites.entry_id                    9HBV 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N     . GLU A 1 34  ? 93.476  159.536 138.361 1.00 87.95  ? 34  GLU C N     1 
ATOM   2    C CA    . GLU A 1 34  ? 94.447  160.621 138.301 1.00 97.91  ? 34  GLU C CA    1 
ATOM   3    C C     . GLU A 1 34  ? 95.825  160.134 138.732 1.00 98.97  ? 34  GLU C C     1 
ATOM   4    O O     . GLU A 1 34  ? 96.630  160.905 139.256 1.00 97.72  ? 34  GLU C O     1 
ATOM   5    C CB    . GLU A 1 34  ? 93.999  161.782 139.174 1.00 93.92  ? 34  GLU C CB    1 
ATOM   6    N N     . LEU A 1 35  ? 96.090  158.851 138.512 1.00 93.75  ? 35  LEU C N     1 
ATOM   7    C CA    . LEU A 1 35  ? 97.365  158.265 138.883 1.00 84.99  ? 35  LEU C CA    1 
ATOM   8    C C     . LEU A 1 35  ? 98.456  158.686 137.904 1.00 86.45  ? 35  LEU C C     1 
ATOM   9    O O     . LEU A 1 35  ? 98.172  159.061 136.764 1.00 88.80  ? 35  LEU C O     1 
ATOM   10   C CB    . LEU A 1 35  ? 97.255  156.745 138.914 1.00 78.88  ? 35  LEU C CB    1 
ATOM   11   C CG    . LEU A 1 35  ? 96.255  156.178 139.922 1.00 80.68  ? 35  LEU C CG    1 
ATOM   12   C CD1   . LEU A 1 35  ? 96.006  154.704 139.655 1.00 81.93  ? 35  LEU C CD1   1 
ATOM   13   C CD2   . LEU A 1 35  ? 96.750  156.392 141.342 1.00 79.84  ? 35  LEU C CD2   1 
ATOM   14   N N     . PRO A 1 36  ? 99.720  158.632 138.323 1.00 78.90  ? 36  PRO C N     1 
ATOM   15   C CA    . PRO A 1 36  ? 100.809 158.952 137.396 1.00 77.45  ? 36  PRO C CA    1 
ATOM   16   C C     . PRO A 1 36  ? 100.866 157.951 136.253 1.00 80.55  ? 36  PRO C C     1 
ATOM   17   O O     . PRO A 1 36  ? 100.412 156.810 136.363 1.00 81.66  ? 36  PRO C O     1 
ATOM   18   C CB    . PRO A 1 36  ? 102.067 158.873 138.271 1.00 70.88  ? 36  PRO C CB    1 
ATOM   19   C CG    . PRO A 1 36  ? 101.585 158.936 139.673 1.00 73.45  ? 36  PRO C CG    1 
ATOM   20   C CD    . PRO A 1 36  ? 100.214 158.350 139.680 1.00 73.99  ? 36  PRO C CD    1 
ATOM   21   N N     . ARG A 1 37  ? 101.429 158.401 135.130 1.00 78.41  ? 37  ARG C N     1 
ATOM   22   C CA    . ARG A 1 37  ? 101.541 157.529 133.967 1.00 73.81  ? 37  ARG C CA    1 
ATOM   23   C C     . ARG A 1 37  ? 102.269 156.235 134.306 1.00 72.60  ? 37  ARG C C     1 
ATOM   24   O O     . ARG A 1 37  ? 101.955 155.182 133.742 1.00 72.33  ? 37  ARG C O     1 
ATOM   25   C CB    . ARG A 1 37  ? 102.263 158.257 132.834 1.00 74.86  ? 37  ARG C CB    1 
ATOM   26   C CG    . ARG A 1 37  ? 101.393 159.250 132.081 1.00 75.24  ? 37  ARG C CG    1 
ATOM   27   C CD    . ARG A 1 37  ? 100.470 158.552 131.092 1.00 79.70  ? 37  ARG C CD    1 
ATOM   28   N NE    . ARG A 1 37  ? 101.207 157.827 130.064 1.00 82.39  ? 37  ARG C NE    1 
ATOM   29   C CZ    . ARG A 1 37  ? 100.660 156.967 129.215 1.00 81.05  ? 37  ARG C CZ    1 
ATOM   30   N NH1   . ARG A 1 37  ? 99.365  156.694 129.243 1.00 82.66  ? 37  ARG C NH1   1 
ATOM   31   N NH2   . ARG A 1 37  ? 101.432 156.364 128.315 1.00 73.59  ? 37  ARG C NH2   1 
ATOM   32   N N     . ASN A 1 38  ? 103.230 156.290 135.231 1.00 77.06  ? 38  ASN C N     1 
ATOM   33   C CA    . ASN A 1 38  ? 104.012 155.102 135.558 1.00 73.12  ? 38  ASN C CA    1 
ATOM   34   C C     . ASN A 1 38  ? 103.115 153.975 136.055 1.00 70.55  ? 38  ASN C C     1 
ATOM   35   O O     . ASN A 1 38  ? 103.181 152.846 135.555 1.00 71.01  ? 38  ASN C O     1 
ATOM   36   C CB    . ASN A 1 38  ? 105.071 155.447 136.606 1.00 75.24  ? 38  ASN C CB    1 
ATOM   37   C CG    . ASN A 1 38  ? 105.857 156.694 136.252 1.00 88.70  ? 38  ASN C CG    1 
ATOM   38   O OD1   . ASN A 1 38  ? 105.522 157.404 135.304 1.00 90.32  ? 38  ASN C OD1   1 
ATOM   39   N ND2   . ASN A 1 38  ? 106.907 156.970 137.016 1.00 100.60 ? 38  ASN C ND2   1 
ATOM   40   N N     . LEU A 1 39  ? 102.264 154.264 137.039 1.00 68.14  ? 39  LEU C N     1 
ATOM   41   C CA    . LEU A 1 39  ? 101.384 153.238 137.588 1.00 65.63  ? 39  LEU C CA    1 
ATOM   42   C C     . LEU A 1 39  ? 100.202 152.954 136.673 1.00 64.55  ? 39  LEU C C     1 
ATOM   43   O O     . LEU A 1 39  ? 99.693  151.827 136.656 1.00 63.99  ? 39  LEU C O     1 
ATOM   44   C CB    . LEU A 1 39  ? 100.888 153.659 138.970 1.00 67.39  ? 39  LEU C CB    1 
ATOM   45   C CG    . LEU A 1 39  ? 101.929 154.339 139.863 1.00 65.52  ? 39  LEU C CG    1 
ATOM   46   C CD1   . LEU A 1 39  ? 101.348 154.620 141.234 1.00 66.37  ? 39  LEU C CD1   1 
ATOM   47   C CD2   . LEU A 1 39  ? 103.184 153.491 139.977 1.00 60.38  ? 39  LEU C CD2   1 
ATOM   48   N N     . GLU A 1 40  ? 99.748  153.955 135.917 1.00 64.45  ? 40  GLU C N     1 
ATOM   49   C CA    . GLU A 1 40  ? 98.661  153.728 134.971 1.00 67.27  ? 40  GLU C CA    1 
ATOM   50   C C     . GLU A 1 40  ? 99.072  152.717 133.911 1.00 70.91  ? 40  GLU C C     1 
ATOM   51   O O     . GLU A 1 40  ? 98.274  151.858 133.514 1.00 69.74  ? 40  GLU C O     1 
ATOM   52   C CB    . GLU A 1 40  ? 98.245  155.054 134.330 1.00 73.23  ? 40  GLU C CB    1 
ATOM   53   C CG    . GLU A 1 40  ? 97.417  154.931 133.052 1.00 80.57  ? 40  GLU C CG    1 
ATOM   54   C CD    . GLU A 1 40  ? 96.049  154.320 133.289 1.00 83.23  ? 40  GLU C CD    1 
ATOM   55   O OE1   . GLU A 1 40  ? 95.855  153.670 134.337 1.00 79.87  ? 40  GLU C OE1   1 
ATOM   56   O OE2   . GLU A 1 40  ? 95.166  154.488 132.422 1.00 77.96  ? 40  GLU C OE2   1 
ATOM   57   N N     . VAL A 1 41  ? 100.316 152.805 133.437 1.00 71.77  ? 41  VAL C N     1 
ATOM   58   C CA    . VAL A 1 41  ? 100.801 151.853 132.444 1.00 61.43  ? 41  VAL C CA    1 
ATOM   59   C C     . VAL A 1 41  ? 100.757 150.440 133.006 1.00 60.82  ? 41  VAL C C     1 
ATOM   60   O O     . VAL A 1 41  ? 100.316 149.502 132.335 1.00 62.93  ? 41  VAL C O     1 
ATOM   61   C CB    . VAL A 1 41  ? 102.221 152.230 131.988 1.00 58.62  ? 41  VAL C CB    1 
ATOM   62   C CG1   . VAL A 1 41  ? 102.885 151.055 131.293 1.00 57.18  ? 41  VAL C CG1   1 
ATOM   63   C CG2   . VAL A 1 41  ? 102.177 153.438 131.074 1.00 64.40  ? 41  VAL C CG2   1 
ATOM   64   N N     . PHE A 1 42  ? 101.220 150.265 134.246 1.00 58.17  ? 42  PHE C N     1 
ATOM   65   C CA    . PHE A 1 42  ? 101.225 148.931 134.838 1.00 57.49  ? 42  PHE C CA    1 
ATOM   66   C C     . PHE A 1 42  ? 99.808  148.412 135.036 1.00 58.39  ? 42  PHE C C     1 
ATOM   67   O O     . PHE A 1 42  ? 99.533  147.234 134.782 1.00 58.53  ? 42  PHE C O     1 
ATOM   68   C CB    . PHE A 1 42  ? 101.978 148.938 136.167 1.00 52.61  ? 42  PHE C CB    1 
ATOM   69   C CG    . PHE A 1 42  ? 102.097 147.579 136.798 1.00 49.44  ? 42  PHE C CG    1 
ATOM   70   C CD1   . PHE A 1 42  ? 101.115 147.107 137.649 1.00 49.32  ? 42  PHE C CD1   1 
ATOM   71   C CD2   . PHE A 1 42  ? 103.188 146.772 136.538 1.00 44.62  ? 42  PHE C CD2   1 
ATOM   72   C CE1   . PHE A 1 42  ? 101.222 145.862 138.227 1.00 43.62  ? 42  PHE C CE1   1 
ATOM   73   C CE2   . PHE A 1 42  ? 103.297 145.525 137.117 1.00 37.88  ? 42  PHE C CE2   1 
ATOM   74   C CZ    . PHE A 1 42  ? 102.313 145.071 137.961 1.00 37.39  ? 42  PHE C CZ    1 
ATOM   75   N N     . ASN A 1 43  ? 98.896  149.272 135.489 1.00 62.58  ? 43  ASN C N     1 
ATOM   76   C CA    . ASN A 1 43  ? 97.514  148.845 135.667 1.00 65.71  ? 43  ASN C CA    1 
ATOM   77   C C     . ASN A 1 43  ? 96.912  148.391 134.343 1.00 66.57  ? 43  ASN C C     1 
ATOM   78   O O     . ASN A 1 43  ? 96.289  147.324 134.261 1.00 66.66  ? 43  ASN C O     1 
ATOM   79   C CB    . ASN A 1 43  ? 96.694  149.984 136.272 1.00 70.32  ? 43  ASN C CB    1 
ATOM   80   C CG    . ASN A 1 43  ? 96.814  150.050 137.776 1.00 68.17  ? 43  ASN C CG    1 
ATOM   81   O OD1   . ASN A 1 43  ? 96.869  149.024 138.453 1.00 62.31  ? 43  ASN C OD1   1 
ATOM   82   N ND2   . ASN A 1 43  ? 96.876  151.263 138.309 1.00 68.77  ? 43  ASN C ND2   1 
ATOM   83   N N     . GLU A 1 44  ? 97.101  149.187 133.289 1.00 67.26  ? 44  GLU C N     1 
ATOM   84   C CA    . GLU A 1 44  ? 96.536  148.834 131.991 1.00 70.24  ? 44  GLU C CA    1 
ATOM   85   C C     . GLU A 1 44  ? 97.159  147.556 131.449 1.00 66.75  ? 44  GLU C C     1 
ATOM   86   O O     . GLU A 1 44  ? 96.459  146.704 130.890 1.00 67.98  ? 44  GLU C O     1 
ATOM   87   C CB    . GLU A 1 44  ? 96.730  149.987 131.008 1.00 74.31  ? 44  GLU C CB    1 
ATOM   88   C CG    . GLU A 1 44  ? 95.641  151.045 131.073 1.00 74.48  ? 44  GLU C CG    1 
ATOM   89   C CD    . GLU A 1 44  ? 94.291  150.531 130.617 1.00 77.44  ? 44  GLU C CD    1 
ATOM   90   O OE1   . GLU A 1 44  ? 94.183  149.326 130.305 1.00 79.98  ? 44  GLU C OE1   1 
ATOM   91   O OE2   . GLU A 1 44  ? 93.334  151.332 130.572 1.00 80.88  ? 44  GLU C OE2   1 
ATOM   92   N N     . ALA A 1 45  ? 98.477  147.404 131.597 1.00 60.45  ? 45  ALA C N     1 
ATOM   93   C CA    . ALA A 1 45  ? 99.144  146.203 131.107 1.00 56.67  ? 45  ALA C CA    1 
ATOM   94   C C     . ALA A 1 45  ? 98.641  144.965 131.833 1.00 58.46  ? 45  ALA C C     1 
ATOM   95   O O     . ALA A 1 45  ? 98.339  143.942 131.207 1.00 61.06  ? 45  ALA C O     1 
ATOM   96   C CB    . ALA A 1 45  ? 100.656 146.347 131.272 1.00 54.36  ? 45  ALA C CB    1 
ATOM   97   N N     . CYS A 1 46  ? 98.549  145.037 133.163 1.00 63.68  ? 46  CYS C N     1 
ATOM   98   C CA    . CYS A 1 46  ? 98.059  143.895 133.924 1.00 65.69  ? 46  CYS C CA    1 
ATOM   99   C C     . CYS A 1 46  ? 96.629  143.557 133.535 1.00 65.87  ? 46  CYS C C     1 
ATOM   100  O O     . CYS A 1 46  ? 96.289  142.382 133.357 1.00 67.00  ? 46  CYS C O     1 
ATOM   101  C CB    . CYS A 1 46  ? 98.157  144.180 135.422 1.00 63.41  ? 46  CYS C CB    1 
ATOM   102  S SG    . CYS A 1 46  ? 99.602  143.442 136.215 1.00 67.05  ? 46  CYS C SG    1 
ATOM   103  N N     . GLY A 1 47  ? 95.776  144.572 133.387 1.00 66.23  ? 47  GLY C N     1 
ATOM   104  C CA    . GLY A 1 47  ? 94.416  144.303 132.955 1.00 68.17  ? 47  GLY C CA    1 
ATOM   105  C C     . GLY A 1 47  ? 94.374  143.613 131.606 1.00 69.27  ? 47  GLY C C     1 
ATOM   106  O O     . GLY A 1 47  ? 93.745  142.565 131.450 1.00 72.42  ? 47  GLY C O     1 
ATOM   107  N N     . HIS A 1 48  ? 95.101  144.157 130.628 1.00 67.61  ? 48  HIS C N     1 
ATOM   108  C CA    . HIS A 1 48  ? 95.062  143.600 129.280 1.00 72.79  ? 48  HIS C CA    1 
ATOM   109  C C     . HIS A 1 48  ? 95.589  142.172 129.252 1.00 68.12  ? 48  HIS C C     1 
ATOM   110  O O     . HIS A 1 48  ? 95.063  141.325 128.521 1.00 72.09  ? 48  HIS C O     1 
ATOM   111  C CB    . HIS A 1 48  ? 95.865  144.482 128.325 1.00 75.65  ? 48  HIS C CB    1 
ATOM   112  C CG    . HIS A 1 48  ? 95.015  145.281 127.388 1.00 81.97  ? 48  HIS C CG    1 
ATOM   113  N ND1   . HIS A 1 48  ? 94.603  144.799 126.164 1.00 86.72  ? 48  HIS C ND1   1 
ATOM   114  C CD2   . HIS A 1 48  ? 94.496  146.526 127.497 1.00 84.70  ? 48  HIS C CD2   1 
ATOM   115  C CE1   . HIS A 1 48  ? 93.868  145.715 125.558 1.00 90.28  ? 48  HIS C CE1   1 
ATOM   116  N NE2   . HIS A 1 48  ? 93.788  146.772 126.346 1.00 90.86  ? 48  HIS C NE2   1 
ATOM   117  N N     . VAL A 1 49  ? 96.624  141.882 130.038 1.00 63.92  ? 49  VAL C N     1 
ATOM   118  C CA    . VAL A 1 49  ? 97.255  140.570 129.968 1.00 63.29  ? 49  VAL C CA    1 
ATOM   119  C C     . VAL A 1 49  ? 96.577  139.518 130.840 1.00 66.81  ? 49  VAL C C     1 
ATOM   120  O O     . VAL A 1 49  ? 96.742  138.319 130.578 1.00 66.54  ? 49  VAL C O     1 
ATOM   121  C CB    . VAL A 1 49  ? 98.741  140.669 130.355 1.00 61.84  ? 49  VAL C CB    1 
ATOM   122  C CG1   . VAL A 1 49  ? 99.377  139.288 130.406 1.00 58.60  ? 49  VAL C CG1   1 
ATOM   123  C CG2   . VAL A 1 49  ? 99.482  141.560 129.377 1.00 61.06  ? 49  VAL C CG2   1 
ATOM   124  N N     . PHE A 1 50  ? 95.811  139.921 131.862 1.00 71.92  ? 50  PHE C N     1 
ATOM   125  C CA    . PHE A 1 50  ? 95.267  138.960 132.813 1.00 67.29  ? 50  PHE C CA    1 
ATOM   126  C C     . PHE A 1 50  ? 93.756  139.057 132.996 1.00 73.43  ? 50  PHE C C     1 
ATOM   127  O O     . PHE A 1 50  ? 93.217  138.393 133.888 1.00 70.89  ? 50  PHE C O     1 
ATOM   128  C CB    . PHE A 1 50  ? 95.956  139.125 134.170 1.00 60.64  ? 50  PHE C CB    1 
ATOM   129  C CG    . PHE A 1 50  ? 97.417  138.789 134.149 1.00 56.47  ? 50  PHE C CG    1 
ATOM   130  C CD1   . PHE A 1 50  ? 97.837  137.473 134.124 1.00 58.15  ? 50  PHE C CD1   1 
ATOM   131  C CD2   . PHE A 1 50  ? 98.371  139.789 134.153 1.00 54.54  ? 50  PHE C CD2   1 
ATOM   132  C CE1   . PHE A 1 50  ? 99.180  137.160 134.106 1.00 55.23  ? 50  PHE C CE1   1 
ATOM   133  C CE2   . PHE A 1 50  ? 99.714  139.482 134.134 1.00 51.24  ? 50  PHE C CE2   1 
ATOM   134  C CZ    . PHE A 1 50  ? 100.118 138.166 134.111 1.00 52.81  ? 50  PHE C CZ    1 
ATOM   135  N N     . GLY A 1 51  ? 93.055  139.848 132.185 1.00 80.60  ? 51  GLY C N     1 
ATOM   136  C CA    . GLY A 1 51  ? 91.606  139.850 132.279 1.00 81.88  ? 51  GLY C CA    1 
ATOM   137  C C     . GLY A 1 51  ? 91.136  140.244 133.663 1.00 80.24  ? 51  GLY C C     1 
ATOM   138  O O     . GLY A 1 51  ? 91.679  141.152 134.301 1.00 73.99  ? 51  GLY C O     1 
ATOM   139  N N     . SER A 1 52  ? 90.100  139.550 134.137 1.00 80.70  ? 52  SER C N     1 
ATOM   140  C CA    . SER A 1 52  ? 89.536  139.812 135.453 1.00 77.79  ? 52  SER C CA    1 
ATOM   141  C C     . SER A 1 52  ? 90.206  139.009 136.559 1.00 76.83  ? 52  SER C C     1 
ATOM   142  O O     . SER A 1 52  ? 89.931  139.264 137.736 1.00 78.77  ? 52  SER C O     1 
ATOM   143  C CB    . SER A 1 52  ? 88.037  139.507 135.445 1.00 77.26  ? 52  SER C CB    1 
ATOM   144  O OG    . SER A 1 52  ? 87.760  138.353 134.671 1.00 73.24  ? 52  SER C OG    1 
ATOM   145  N N     . SER A 1 53  ? 91.071  138.052 136.218 1.00 76.25  ? 53  SER C N     1 
ATOM   146  C CA    . SER A 1 53  ? 91.726  137.235 137.231 1.00 80.13  ? 53  SER C CA    1 
ATOM   147  C C     . SER A 1 53  ? 92.782  138.002 138.015 1.00 77.62  ? 53  SER C C     1 
ATOM   148  O O     . SER A 1 53  ? 93.289  137.477 139.011 1.00 76.34  ? 53  SER C O     1 
ATOM   149  C CB    . SER A 1 53  ? 92.359  136.002 136.580 1.00 75.66  ? 53  SER C CB    1 
ATOM   150  O OG    . SER A 1 53  ? 93.692  136.260 136.181 1.00 73.14  ? 53  SER C OG    1 
ATOM   151  N N     . PHE A 1 54  ? 93.125  139.217 137.595 1.00 71.71  ? 54  PHE C N     1 
ATOM   152  C CA    . PHE A 1 54  ? 94.131  140.021 138.280 1.00 68.72  ? 54  PHE C CA    1 
ATOM   153  C C     . PHE A 1 54  ? 93.479  140.732 139.459 1.00 71.17  ? 54  PHE C C     1 
ATOM   154  O O     . PHE A 1 54  ? 92.619  141.598 139.271 1.00 71.29  ? 54  PHE C O     1 
ATOM   155  C CB    . PHE A 1 54  ? 94.755  141.020 137.312 1.00 71.57  ? 54  PHE C CB    1 
ATOM   156  C CG    . PHE A 1 54  ? 95.683  142.000 137.965 1.00 68.17  ? 54  PHE C CG    1 
ATOM   157  C CD1   . PHE A 1 54  ? 96.948  141.613 138.365 1.00 60.05  ? 54  PHE C CD1   1 
ATOM   158  C CD2   . PHE A 1 54  ? 95.293  143.312 138.169 1.00 68.80  ? 54  PHE C CD2   1 
ATOM   159  C CE1   . PHE A 1 54  ? 97.803  142.513 138.962 1.00 57.03  ? 54  PHE C CE1   1 
ATOM   160  C CE2   . PHE A 1 54  ? 96.147  144.217 138.766 1.00 68.30  ? 54  PHE C CE2   1 
ATOM   161  C CZ    . PHE A 1 54  ? 97.403  143.817 139.162 1.00 60.69  ? 54  PHE C CZ    1 
ATOM   162  N N     . ASN A 1 55  ? 93.890  140.374 140.673 1.00 72.11  ? 55  ASN C N     1 
ATOM   163  C CA    . ASN A 1 55  ? 93.335  140.956 141.888 1.00 72.23  ? 55  ASN C CA    1 
ATOM   164  C C     . ASN A 1 55  ? 94.228  142.102 142.348 1.00 67.83  ? 55  ASN C C     1 
ATOM   165  O O     . ASN A 1 55  ? 95.446  141.937 142.468 1.00 63.90  ? 55  ASN C O     1 
ATOM   166  C CB    . ASN A 1 55  ? 93.207  139.901 142.984 1.00 68.19  ? 55  ASN C CB    1 
ATOM   167  C CG    . ASN A 1 55  ? 92.530  140.436 144.229 1.00 71.02  ? 55  ASN C CG    1 
ATOM   168  O OD1   . ASN A 1 55  ? 91.855  141.465 144.187 1.00 68.42  ? 55  ASN C OD1   1 
ATOM   169  N ND2   . ASN A 1 55  ? 92.696  139.734 145.343 1.00 73.62  ? 55  ASN C ND2   1 
ATOM   170  N N     . ARG A 1 56  ? 93.619  143.260 142.610 1.00 69.06  ? 56  ARG C N     1 
ATOM   171  C CA    . ARG A 1 56  ? 94.349  144.473 142.957 1.00 68.21  ? 56  ARG C CA    1 
ATOM   172  C C     . ARG A 1 56  ? 94.497  144.661 144.462 1.00 70.31  ? 56  ARG C C     1 
ATOM   173  O O     . ARG A 1 56  ? 94.678  145.795 144.924 1.00 69.31  ? 56  ARG C O     1 
ATOM   174  C CB    . ARG A 1 56  ? 93.650  145.685 142.338 1.00 72.34  ? 56  ARG C CB    1 
ATOM   175  C CG    . ARG A 1 56  ? 94.535  146.908 142.177 1.00 73.92  ? 56  ARG C CG    1 
ATOM   176  C CD    . ARG A 1 56  ? 93.755  148.083 141.617 1.00 79.82  ? 56  ARG C CD    1 
ATOM   177  N NE    . ARG A 1 56  ? 94.588  149.269 141.468 1.00 82.52  ? 56  ARG C NE    1 
ATOM   178  C CZ    . ARG A 1 56  ? 94.191  150.396 140.895 1.00 83.49  ? 56  ARG C CZ    1 
ATOM   179  N NH1   . ARG A 1 56  ? 92.968  150.531 140.408 1.00 83.94  ? 56  ARG C NH1   1 
ATOM   180  N NH2   . ARG A 1 56  ? 95.041  151.415 140.809 1.00 79.05  ? 56  ARG C NH2   1 
ATOM   181  N N     . GLU A 1 57  ? 94.426  143.581 145.244 1.00 70.18  ? 57  GLU C N     1 
ATOM   182  C CA    . GLU A 1 57  ? 94.505  143.680 146.694 1.00 66.06  ? 57  GLU C CA    1 
ATOM   183  C C     . GLU A 1 57  ? 95.383  142.618 147.342 1.00 63.05  ? 57  GLU C C     1 
ATOM   184  O O     . GLU A 1 57  ? 95.531  142.635 148.568 1.00 60.38  ? 57  GLU C O     1 
ATOM   185  C CB    . GLU A 1 57  ? 93.101  143.599 147.316 1.00 70.81  ? 57  GLU C CB    1 
ATOM   186  C CG    . GLU A 1 57  ? 92.005  144.307 146.528 1.00 77.78  ? 57  GLU C CG    1 
ATOM   187  C CD    . GLU A 1 57  ? 92.114  145.817 146.601 1.00 80.60  ? 57  GLU C CD    1 
ATOM   188  O OE1   . GLU A 1 57  ? 93.192  146.320 146.976 1.00 74.77  ? 57  GLU C OE1   1 
ATOM   189  O OE2   . GLU A 1 57  ? 91.119  146.501 146.279 1.00 89.08  ? 57  GLU C OE2   1 
ATOM   190  N N     . ASP A 1 58  ? 95.964  141.702 146.572 1.00 61.72  ? 58  ASP C N     1 
ATOM   191  C CA    . ASP A 1 58  ? 96.770  140.615 147.112 1.00 58.89  ? 58  ASP C CA    1 
ATOM   192  C C     . ASP A 1 58  ? 98.221  140.803 146.696 1.00 53.65  ? 58  ASP C C     1 
ATOM   193  O O     . ASP A 1 58  ? 98.512  140.988 145.511 1.00 50.68  ? 58  ASP C O     1 
ATOM   194  C CB    . ASP A 1 58  ? 96.254  139.258 146.627 1.00 58.47  ? 58  ASP C CB    1 
ATOM   195  C CG    . ASP A 1 58  ? 95.204  138.664 147.552 1.00 63.25  ? 58  ASP C CG    1 
ATOM   196  O OD1   . ASP A 1 58  ? 95.024  139.181 148.674 1.00 64.77  ? 58  ASP C OD1   1 
ATOM   197  O OD2   . ASP A 1 58  ? 94.554  137.675 147.152 1.00 68.12  ? 58  ASP C OD2   1 
ATOM   198  N N     . ASN A 1 59  ? 99.125  140.755 147.675 1.00 49.96  ? 59  ASN C N     1 
ATOM   199  C CA    . ASN A 1 59  ? 100.536 140.992 147.389 1.00 43.64  ? 59  ASN C CA    1 
ATOM   200  C C     . ASN A 1 59  ? 101.117 139.903 146.498 1.00 47.09  ? 59  ASN C C     1 
ATOM   201  O O     . ASN A 1 59  ? 101.854 140.197 145.552 1.00 56.14  ? 59  ASN C O     1 
ATOM   202  C CB    . ASN A 1 59  ? 101.323 141.086 148.692 1.00 42.74  ? 59  ASN C CB    1 
ATOM   203  C CG    . ASN A 1 59  ? 101.125 142.406 149.393 1.00 41.95  ? 59  ASN C CG    1 
ATOM   204  O OD1   . ASN A 1 59  ? 101.050 143.455 148.756 1.00 44.28  ? 59  ASN C OD1   1 
ATOM   205  N ND2   . ASN A 1 59  ? 101.038 142.364 150.714 1.00 40.46  ? 59  ASN C ND2   1 
ATOM   206  N N     . SER A 1 60  ? 100.808 138.639 146.786 1.00 46.04  ? 60  SER C N     1 
ATOM   207  C CA    . SER A 1 60  ? 101.364 137.553 145.985 1.00 48.79  ? 60  SER C CA    1 
ATOM   208  C C     . SER A 1 60  ? 100.893 137.644 144.541 1.00 48.58  ? 60  SER C C     1 
ATOM   209  O O     . SER A 1 60  ? 101.683 137.453 143.608 1.00 48.40  ? 60  SER C O     1 
ATOM   210  C CB    . SER A 1 60  ? 100.976 136.206 146.591 1.00 57.60  ? 60  SER C CB    1 
ATOM   211  O OG    . SER A 1 60  ? 101.081 136.232 148.004 1.00 59.06  ? 60  SER C OG    1 
ATOM   212  N N     . VAL A 1 61  ? 99.609  137.938 144.336 1.00 47.63  ? 61  VAL C N     1 
ATOM   213  C CA    . VAL A 1 61  ? 99.068  138.022 142.982 1.00 49.61  ? 61  VAL C CA    1 
ATOM   214  C C     . VAL A 1 61  ? 99.752  139.141 142.207 1.00 51.07  ? 61  VAL C C     1 
ATOM   215  O O     . VAL A 1 61  ? 100.168 138.961 141.056 1.00 52.08  ? 61  VAL C O     1 
ATOM   216  C CB    . VAL A 1 61  ? 97.543  138.223 143.032 1.00 52.12  ? 61  VAL C CB    1 
ATOM   217  C CG1   . VAL A 1 61  ? 96.996  138.519 141.650 1.00 57.57  ? 61  VAL C CG1   1 
ATOM   218  C CG2   . VAL A 1 61  ? 96.869  136.999 143.623 1.00 55.41  ? 61  VAL C CG2   1 
ATOM   219  N N     . ILE A 1 62  ? 99.880  140.315 142.827 1.00 46.90  ? 62  ILE C N     1 
ATOM   220  C CA    . ILE A 1 62  ? 100.495 141.444 142.139 1.00 39.94  ? 62  ILE C CA    1 
ATOM   221  C C     . ILE A 1 62  ? 101.960 141.159 141.849 1.00 35.31  ? 62  ILE C C     1 
ATOM   222  O O     . ILE A 1 62  ? 102.465 141.492 140.774 1.00 43.54  ? 62  ILE C O     1 
ATOM   223  C CB    . ILE A 1 62  ? 100.325 142.734 142.959 1.00 40.92  ? 62  ILE C CB    1 
ATOM   224  C CG1   . ILE A 1 62  ? 98.870  143.194 142.922 1.00 48.09  ? 62  ILE C CG1   1 
ATOM   225  C CG2   . ILE A 1 62  ? 101.222 143.824 142.412 1.00 39.35  ? 62  ILE C CG2   1 
ATOM   226  C CD1   . ILE A 1 62  ? 98.492  144.102 144.066 1.00 54.65  ? 62  ILE C CD1   1 
ATOM   227  N N     . SER A 1 63  ? 102.670 140.555 142.800 1.00 32.86  ? 63  SER C N     1 
ATOM   228  C CA    . SER A 1 63  ? 104.076 140.240 142.572 1.00 33.71  ? 63  SER C CA    1 
ATOM   229  C C     . SER A 1 63  ? 104.242 139.249 141.427 1.00 42.23  ? 63  SER C C     1 
ATOM   230  O O     . SER A 1 63  ? 105.136 139.409 140.589 1.00 48.23  ? 63  SER C O     1 
ATOM   231  C CB    . SER A 1 63  ? 104.705 139.696 143.851 1.00 39.88  ? 63  SER C CB    1 
ATOM   232  O OG    . SER A 1 63  ? 104.723 140.688 144.863 1.00 40.96  ? 63  SER C OG    1 
ATOM   233  N N     . ASP A 1 64  ? 103.395 138.218 141.371 1.00 46.97  ? 64  ASP C N     1 
ATOM   234  C CA    . ASP A 1 64  ? 103.489 137.250 140.280 1.00 48.34  ? 64  ASP C CA    1 
ATOM   235  C C     . ASP A 1 64  ? 103.156 137.893 138.937 1.00 43.13  ? 64  ASP C C     1 
ATOM   236  O O     . ASP A 1 64  ? 103.823 137.625 137.929 1.00 42.64  ? 64  ASP C O     1 
ATOM   237  C CB    . ASP A 1 64  ? 102.564 136.065 140.551 1.00 53.68  ? 64  ASP C CB    1 
ATOM   238  C CG    . ASP A 1 64  ? 103.047 135.200 141.701 1.00 61.44  ? 64  ASP C CG    1 
ATOM   239  O OD1   . ASP A 1 64  ? 104.269 134.967 141.801 1.00 61.55  ? 64  ASP C OD1   1 
ATOM   240  O OD2   . ASP A 1 64  ? 102.204 134.754 142.507 1.00 64.22  ? 64  ASP C OD2   1 
ATOM   241  N N     . ALA A 1 65  ? 102.130 138.748 138.903 1.00 39.27  ? 65  ALA C N     1 
ATOM   242  C CA    . ALA A 1 65  ? 101.790 139.438 137.664 1.00 41.46  ? 65  ALA C CA    1 
ATOM   243  C C     . ALA A 1 65  ? 102.927 140.341 137.206 1.00 38.08  ? 65  ALA C C     1 
ATOM   244  O O     . ALA A 1 65  ? 103.257 140.384 136.015 1.00 43.51  ? 65  ALA C O     1 
ATOM   245  C CB    . ALA A 1 65  ? 100.509 140.248 137.853 1.00 43.56  ? 65  ALA C CB    1 
ATOM   246  N N     . ALA A 1 66  ? 103.535 141.076 138.138 1.00 33.81  ? 66  ALA C N     1 
ATOM   247  C CA    . ALA A 1 66  ? 104.649 141.945 137.785 1.00 27.63  ? 66  ALA C CA    1 
ATOM   248  C C     . ALA A 1 66  ? 105.839 141.137 137.296 1.00 30.55  ? 66  ALA C C     1 
ATOM   249  O O     . ALA A 1 66  ? 106.534 141.551 136.366 1.00 39.74  ? 66  ALA C O     1 
ATOM   250  C CB    . ALA A 1 66  ? 105.044 142.806 138.980 1.00 34.57  ? 66  ALA C CB    1 
ATOM   251  N N     . ALA A 1 67  ? 106.099 139.986 137.914 1.00 30.60  ? 67  ALA C N     1 
ATOM   252  C CA    . ALA A 1 67  ? 107.188 139.137 137.441 1.00 35.43  ? 67  ALA C CA    1 
ATOM   253  C C     . ALA A 1 67  ? 106.927 138.653 136.022 1.00 41.98  ? 67  ALA C C     1 
ATOM   254  O O     . ALA A 1 67  ? 107.833 138.658 135.179 1.00 48.02  ? 67  ALA C O     1 
ATOM   255  C CB    . ALA A 1 67  ? 107.376 137.951 138.383 1.00 38.33  ? 67  ALA C CB    1 
ATOM   256  N N     . PHE A 1 68  ? 105.695 138.227 135.735 1.00 42.89  ? 68  PHE C N     1 
ATOM   257  C CA    . PHE A 1 68  ? 105.387 137.775 134.381 1.00 43.17  ? 68  PHE C CA    1 
ATOM   258  C C     . PHE A 1 68  ? 105.531 138.910 133.376 1.00 40.89  ? 68  PHE C C     1 
ATOM   259  O O     . PHE A 1 68  ? 106.081 138.715 132.287 1.00 41.41  ? 68  PHE C O     1 
ATOM   260  C CB    . PHE A 1 68  ? 103.978 137.193 134.314 1.00 47.67  ? 68  PHE C CB    1 
ATOM   261  C CG    . PHE A 1 68  ? 103.595 136.706 132.942 1.00 53.05  ? 68  PHE C CG    1 
ATOM   262  C CD1   . PHE A 1 68  ? 104.099 135.514 132.450 1.00 54.85  ? 68  PHE C CD1   1 
ATOM   263  C CD2   . PHE A 1 68  ? 102.742 137.446 132.141 1.00 51.33  ? 68  PHE C CD2   1 
ATOM   264  C CE1   . PHE A 1 68  ? 103.753 135.068 131.191 1.00 54.09  ? 68  PHE C CE1   1 
ATOM   265  C CE2   . PHE A 1 68  ? 102.394 137.003 130.881 1.00 50.57  ? 68  PHE C CE2   1 
ATOM   266  C CZ    . PHE A 1 68  ? 102.901 135.814 130.407 1.00 55.23  ? 68  PHE C CZ    1 
ATOM   267  N N     . LEU A 1 69  ? 105.037 140.101 133.716 1.00 41.28  ? 69  LEU C N     1 
ATOM   268  C CA    . LEU A 1 69  ? 105.166 141.230 132.799 1.00 37.28  ? 69  LEU C CA    1 
ATOM   269  C C     . LEU A 1 69  ? 106.627 141.605 132.594 1.00 39.04  ? 69  LEU C C     1 
ATOM   270  O O     . LEU A 1 69  ? 107.028 141.983 131.489 1.00 43.85  ? 69  LEU C O     1 
ATOM   271  C CB    . LEU A 1 69  ? 104.376 142.430 133.315 1.00 36.14  ? 69  LEU C CB    1 
ATOM   272  C CG    . LEU A 1 69  ? 102.908 142.486 132.900 1.00 36.41  ? 69  LEU C CG    1 
ATOM   273  C CD1   . LEU A 1 69  ? 102.193 143.592 133.641 1.00 42.87  ? 69  LEU C CD1   1 
ATOM   274  C CD2   . LEU A 1 69  ? 102.787 142.687 131.405 1.00 47.76  ? 69  LEU C CD2   1 
ATOM   275  N N     . PHE A 1 70  ? 107.436 141.524 133.650 1.00 39.46  ? 70  PHE C N     1 
ATOM   276  C CA    . PHE A 1 70  ? 108.860 141.793 133.507 1.00 37.84  ? 70  PHE C CA    1 
ATOM   277  C C     . PHE A 1 70  ? 109.511 140.789 132.570 1.00 44.28  ? 70  PHE C C     1 
ATOM   278  O O     . PHE A 1 70  ? 110.324 141.160 131.717 1.00 51.25  ? 70  PHE C O     1 
ATOM   279  C CB    . PHE A 1 70  ? 109.536 141.762 134.875 1.00 35.97  ? 70  PHE C CB    1 
ATOM   280  C CG    . PHE A 1 70  ? 110.976 142.167 134.849 1.00 35.33  ? 70  PHE C CG    1 
ATOM   281  C CD1   . PHE A 1 70  ? 111.344 143.436 134.451 1.00 37.20  ? 70  PHE C CD1   1 
ATOM   282  C CD2   . PHE A 1 70  ? 111.962 141.282 135.232 1.00 40.29  ? 70  PHE C CD2   1 
ATOM   283  C CE1   . PHE A 1 70  ? 112.666 143.811 134.431 1.00 37.33  ? 70  PHE C CE1   1 
ATOM   284  C CE2   . PHE A 1 70  ? 113.285 141.653 135.212 1.00 46.45  ? 70  PHE C CE2   1 
ATOM   285  C CZ    . PHE A 1 70  ? 113.636 142.920 134.811 1.00 42.18  ? 70  PHE C CZ    1 
ATOM   286  N N     . LYS A 1 71  ? 109.168 139.507 132.712 1.00 42.22  ? 71  LYS C N     1 
ATOM   287  C CA    . LYS A 1 71  ? 109.707 138.512 131.793 1.00 43.85  ? 71  LYS C CA    1 
ATOM   288  C C     . LYS A 1 71  ? 109.259 138.782 130.365 1.00 50.65  ? 71  LYS C C     1 
ATOM   289  O O     . LYS A 1 71  ? 110.055 138.648 129.430 1.00 55.18  ? 71  LYS C O     1 
ATOM   290  C CB    . LYS A 1 71  ? 109.287 137.108 132.221 1.00 43.45  ? 71  LYS C CB    1 
ATOM   291  C CG    . LYS A 1 71  ? 110.096 136.555 133.376 1.00 47.38  ? 71  LYS C CG    1 
ATOM   292  C CD    . LYS A 1 71  ? 109.740 135.108 133.665 1.00 47.85  ? 71  LYS C CD    1 
ATOM   293  C CE    . LYS A 1 71  ? 110.787 134.160 133.105 1.00 50.59  ? 71  LYS C CE    1 
ATOM   294  N NZ    . LYS A 1 71  ? 110.530 132.749 133.498 1.00 53.45  ? 71  LYS C NZ    1 
ATOM   295  N N     . MET A 1 72  ? 107.997 139.167 130.178 1.00 51.10  ? 72  MET C N     1 
ATOM   296  C CA    . MET A 1 72  ? 107.490 139.429 128.836 1.00 48.99  ? 72  MET C CA    1 
ATOM   297  C C     . MET A 1 72  ? 108.185 140.627 128.206 1.00 46.34  ? 72  MET C C     1 
ATOM   298  O O     . MET A 1 72  ? 108.479 140.621 127.006 1.00 52.49  ? 72  MET C O     1 
ATOM   299  C CB    . MET A 1 72  ? 105.981 139.656 128.887 1.00 47.55  ? 72  MET C CB    1 
ATOM   300  C CG    . MET A 1 72  ? 105.326 139.805 127.532 1.00 48.45  ? 72  MET C CG    1 
ATOM   301  S SD    . MET A 1 72  ? 103.738 140.642 127.641 1.00 55.00  ? 72  MET C SD    1 
ATOM   302  C CE    . MET A 1 72  ? 102.874 139.564 128.774 1.00 53.98  ? 72  MET C CE    1 
ATOM   303  N N     . HIS A 1 73  ? 108.446 141.668 128.994 1.00 45.53  ? 73  HIS C N     1 
ATOM   304  C CA    . HIS A 1 73  ? 109.076 142.874 128.480 1.00 43.47  ? 73  HIS C CA    1 
ATOM   305  C C     . HIS A 1 73  ? 110.590 142.755 128.383 1.00 44.61  ? 73  HIS C C     1 
ATOM   306  O O     . HIS A 1 73  ? 111.231 143.665 127.849 1.00 46.93  ? 73  HIS C O     1 
ATOM   307  C CB    . HIS A 1 73  ? 108.705 144.067 129.360 1.00 42.83  ? 73  HIS C CB    1 
ATOM   308  C CG    . HIS A 1 73  ? 107.416 144.719 128.973 1.00 39.86  ? 73  HIS C CG    1 
ATOM   309  N ND1   . HIS A 1 73  ? 107.334 146.040 128.592 1.00 40.15  ? 73  HIS C ND1   1 
ATOM   310  C CD2   . HIS A 1 73  ? 106.157 144.228 128.896 1.00 42.28  ? 73  HIS C CD2   1 
ATOM   311  C CE1   . HIS A 1 73  ? 106.080 146.336 128.302 1.00 42.91  ? 73  HIS C CE1   1 
ATOM   312  N NE2   . HIS A 1 73  ? 105.346 145.253 128.479 1.00 42.74  ? 73  HIS C NE2   1 
ATOM   313  N N     . THR A 1 74  ? 111.174 141.672 128.887 1.00 40.98  ? 74  THR C N     1 
ATOM   314  C CA    . THR A 1 74  ? 112.594 141.405 128.722 1.00 46.71  ? 74  THR C CA    1 
ATOM   315  C C     . THR A 1 74  ? 112.874 140.375 127.636 1.00 58.23  ? 74  THR C C     1 
ATOM   316  O O     . THR A 1 74  ? 114.024 139.956 127.480 1.00 67.24  ? 74  THR C O     1 
ATOM   317  C CB    . THR A 1 74  ? 113.201 140.931 130.044 1.00 47.97  ? 74  THR C CB    1 
ATOM   318  O OG1   . THR A 1 74  ? 112.339 139.960 130.648 1.00 47.12  ? 74  THR C OG1   1 
ATOM   319  C CG2   . THR A 1 74  ? 113.386 142.099 130.990 1.00 48.68  ? 74  THR C CG2   1 
ATOM   320  N N     . HIS A 1 75  ? 111.857 139.960 126.882 1.00 60.90  ? 75  HIS C N     1 
ATOM   321  C CA    . HIS A 1 75  ? 112.022 138.971 125.819 1.00 62.58  ? 75  HIS C CA    1 
ATOM   322  C C     . HIS A 1 75  ? 112.633 137.683 126.369 1.00 65.93  ? 75  HIS C C     1 
ATOM   323  O O     . HIS A 1 75  ? 113.630 137.170 125.858 1.00 70.24  ? 75  HIS C O     1 
ATOM   324  C CB    . HIS A 1 75  ? 112.868 139.538 124.679 1.00 61.85  ? 75  HIS C CB    1 
ATOM   325  C CG    . HIS A 1 75  ? 112.442 140.902 124.238 1.00 60.27  ? 75  HIS C CG    1 
ATOM   326  N ND1   . HIS A 1 75  ? 113.061 142.052 124.677 1.00 61.09  ? 75  HIS C ND1   1 
ATOM   327  C CD2   . HIS A 1 75  ? 111.457 141.301 123.401 1.00 59.03  ? 75  HIS C CD2   1 
ATOM   328  C CE1   . HIS A 1 75  ? 112.476 143.101 124.127 1.00 62.90  ? 75  HIS C CE1   1 
ATOM   329  N NE2   . HIS A 1 75  ? 111.500 142.673 123.349 1.00 60.68  ? 75  HIS C NE2   1 
ATOM   330  N N     . SER A 1 76  ? 112.021 137.162 127.431 1.00 63.08  ? 76  SER C N     1 
ATOM   331  C CA    . SER A 1 76  ? 112.473 135.935 128.069 1.00 63.29  ? 76  SER C CA    1 
ATOM   332  C C     . SER A 1 76  ? 111.404 134.852 128.105 1.00 67.97  ? 76  SER C C     1 
ATOM   333  O O     . SER A 1 76  ? 111.656 133.775 128.657 1.00 71.96  ? 76  SER C O     1 
ATOM   334  C CB    . SER A 1 76  ? 112.952 136.227 129.497 1.00 59.92  ? 76  SER C CB    1 
ATOM   335  O OG    . SER A 1 76  ? 114.307 136.639 129.500 1.00 56.77  ? 76  SER C OG    1 
ATOM   336  N N     . LEU A 1 77  ? 110.224 135.100 127.545 1.00 68.49  ? 77  LEU C N     1 
ATOM   337  C CA    . LEU A 1 77  ? 109.191 134.082 127.457 1.00 68.73  ? 77  LEU C CA    1 
ATOM   338  C C     . LEU A 1 77  ? 109.487 133.137 126.294 1.00 78.00  ? 77  LEU C C     1 
ATOM   339  O O     . LEU A 1 77  ? 110.432 133.329 125.523 1.00 80.22  ? 77  LEU C O     1 
ATOM   340  C CB    . LEU A 1 77  ? 107.819 134.731 127.293 1.00 64.99  ? 77  LEU C CB    1 
ATOM   341  C CG    . LEU A 1 77  ? 107.277 135.502 128.495 1.00 60.02  ? 77  LEU C CG    1 
ATOM   342  C CD1   . LEU A 1 77  ? 106.018 136.254 128.109 1.00 57.72  ? 77  LEU C CD1   1 
ATOM   343  C CD2   . LEU A 1 77  ? 107.001 134.565 129.655 1.00 62.30  ? 77  LEU C CD2   1 
ATOM   344  N N     . ASP A 1 78  ? 108.671 132.094 126.165 1.00 83.12  ? 78  ASP C N     1 
ATOM   345  C CA    . ASP A 1 78  ? 108.783 131.183 125.036 1.00 83.26  ? 78  ASP C CA    1 
ATOM   346  C C     . ASP A 1 78  ? 108.177 131.813 123.789 1.00 82.78  ? 78  ASP C C     1 
ATOM   347  O O     . ASP A 1 78  ? 107.136 132.472 123.850 1.00 79.40  ? 78  ASP C O     1 
ATOM   348  C CB    . ASP A 1 78  ? 108.086 129.858 125.343 1.00 85.13  ? 78  ASP C CB    1 
ATOM   349  C CG    . ASP A 1 78  ? 108.849 129.015 126.347 1.00 91.46  ? 78  ASP C CG    1 
ATOM   350  O OD1   . ASP A 1 78  ? 110.086 129.160 126.428 1.00 92.89  ? 78  ASP C OD1   1 
ATOM   351  O OD2   . ASP A 1 78  ? 108.211 128.204 127.050 1.00 95.95  ? 78  ASP C OD2   1 
ATOM   352  N N     . GLY A 1 79  ? 108.838 131.604 122.654 1.00 85.75  ? 79  GLY C N     1 
ATOM   353  C CA    . GLY A 1 79  ? 108.386 132.143 121.390 1.00 84.64  ? 79  GLY C CA    1 
ATOM   354  C C     . GLY A 1 79  ? 108.829 133.559 121.102 1.00 83.35  ? 79  GLY C C     1 
ATOM   355  O O     . GLY A 1 79  ? 108.503 134.084 120.029 1.00 84.55  ? 79  GLY C O     1 
ATOM   356  N N     . GLN A 1 80  ? 109.558 134.194 122.013 1.00 80.61  ? 80  GLN C N     1 
ATOM   357  C CA    . GLN A 1 80  ? 110.040 135.549 121.807 1.00 82.08  ? 80  GLN C CA    1 
ATOM   358  C C     . GLN A 1 80  ? 111.427 135.526 121.170 1.00 83.51  ? 80  GLN C C     1 
ATOM   359  O O     . GLN A 1 80  ? 112.094 134.493 121.103 1.00 85.45  ? 80  GLN C O     1 
ATOM   360  C CB    . GLN A 1 80  ? 110.070 136.312 123.130 1.00 76.23  ? 80  GLN C CB    1 
ATOM   361  C CG    . GLN A 1 80  ? 108.949 137.328 123.278 1.00 71.02  ? 80  GLN C CG    1 
ATOM   362  C CD    . GLN A 1 80  ? 108.729 137.745 124.715 1.00 63.99  ? 80  GLN C CD    1 
ATOM   363  O OE1   . GLN A 1 80  ? 109.319 137.181 125.635 1.00 65.33  ? 80  GLN C OE1   1 
ATOM   364  N NE2   . GLN A 1 80  ? 107.875 138.741 124.916 1.00 63.56  ? 80  GLN C NE2   1 
ATOM   365  N N     . GLU A 1 81  ? 111.861 136.695 120.701 1.00 84.14  ? 81  GLU C N     1 
ATOM   366  C CA    . GLU A 1 81  ? 113.128 136.808 119.989 1.00 83.76  ? 81  GLU C CA    1 
ATOM   367  C C     . GLU A 1 81  ? 114.278 136.239 120.810 1.00 89.78  ? 81  GLU C C     1 
ATOM   368  O O     . GLU A 1 81  ? 114.175 136.111 122.034 1.00 92.41  ? 81  GLU C O     1 
ATOM   369  C CB    . GLU A 1 81  ? 113.408 138.266 119.626 1.00 80.73  ? 81  GLU C CB    1 
ATOM   370  C CG    . GLU A 1 81  ? 112.508 138.804 118.531 1.00 84.34  ? 81  GLU C CG    1 
ATOM   371  C CD    . GLU A 1 81  ? 113.282 139.205 117.289 1.00 89.71  ? 81  GLU C CD    1 
ATOM   372  O OE1   . GLU A 1 81  ? 113.907 140.286 117.297 1.00 91.97  ? 81  GLU C OE1   1 
ATOM   373  O OE2   . GLU A 1 81  ? 113.271 138.434 116.306 1.00 88.08  ? 81  GLU C OE2   1 
ATOM   374  N N     . ALA A 1 82  ? 115.370 135.887 120.138 1.00 91.67  ? 82  ALA C N     1 
ATOM   375  C CA    . ALA A 1 82  ? 116.521 135.260 120.770 1.00 93.99  ? 82  ALA C CA    1 
ATOM   376  C C     . ALA A 1 82  ? 117.631 136.280 120.980 1.00 96.03  ? 82  ALA C C     1 
ATOM   377  O O     . ALA A 1 82  ? 117.874 137.137 120.125 1.00 94.45  ? 82  ALA C O     1 
ATOM   378  C CB    . ALA A 1 82  ? 117.035 134.099 119.918 1.00 94.75  ? 82  ALA C CB    1 
ATOM   379  N N     . LYS A 1 83  ? 118.303 136.182 122.127 1.00 98.99  ? 83  LYS C N     1 
ATOM   380  C CA    . LYS A 1 83  ? 119.412 137.071 122.475 1.00 100.08 ? 83  LYS C CA    1 
ATOM   381  C C     . LYS A 1 83  ? 120.691 136.442 121.936 1.00 102.82 ? 83  LYS C C     1 
ATOM   382  O O     . LYS A 1 83  ? 121.318 135.604 122.585 1.00 105.55 ? 83  LYS C O     1 
ATOM   383  C CB    . LYS A 1 83  ? 119.482 137.284 123.982 1.00 97.48  ? 83  LYS C CB    1 
ATOM   384  C CG    . LYS A 1 83  ? 118.136 137.549 124.651 1.00 90.62  ? 83  LYS C CG    1 
ATOM   385  C CD    . LYS A 1 83  ? 118.110 138.897 125.351 1.00 90.96  ? 83  LYS C CD    1 
ATOM   386  C CE    . LYS A 1 83  ? 116.945 138.998 126.321 1.00 83.18  ? 83  LYS C CE    1 
ATOM   387  N NZ    . LYS A 1 83  ? 117.120 138.124 127.513 1.00 83.08  ? 83  LYS C NZ    1 
ATOM   388  N N     . VAL A 1 84  ? 121.084 136.853 120.732 1.00 101.64 ? 84  VAL C N     1 
ATOM   389  C CA    . VAL A 1 84  ? 122.174 136.200 120.016 1.00 105.01 ? 84  VAL C CA    1 
ATOM   390  C C     . VAL A 1 84  ? 123.197 137.228 119.547 1.00 103.48 ? 84  VAL C C     1 
ATOM   391  O O     . VAL A 1 84  ? 123.875 137.027 118.533 1.00 107.68 ? 84  VAL C O     1 
ATOM   392  C CB    . VAL A 1 84  ? 121.623 135.380 118.833 1.00 109.14 ? 84  VAL C CB    1 
ATOM   393  C CG1   . VAL A 1 84  ? 122.738 134.637 118.116 1.00 110.83 ? 84  VAL C CG1   1 
ATOM   394  C CG2   . VAL A 1 84  ? 120.556 134.405 119.316 1.00 105.96 ? 84  VAL C CG2   1 
ATOM   395  N N     . LEU A 1 85  ? 123.324 138.342 120.270 1.00 96.79  ? 85  LEU C N     1 
ATOM   396  C CA    . LEU A 1 85  ? 124.326 139.333 119.889 1.00 98.95  ? 85  LEU C CA    1 
ATOM   397  C C     . LEU A 1 85  ? 125.734 138.778 120.071 1.00 99.51  ? 85  LEU C C     1 
ATOM   398  O O     . LEU A 1 85  ? 126.563 138.848 119.157 1.00 101.89 ? 85  LEU C O     1 
ATOM   399  C CB    . LEU A 1 85  ? 124.145 140.613 120.704 1.00 100.98 ? 85  LEU C CB    1 
ATOM   400  C CG    . LEU A 1 85  ? 125.039 141.791 120.297 1.00 96.98  ? 85  LEU C CG    1 
ATOM   401  C CD1   . LEU A 1 85  ? 124.772 142.210 118.857 1.00 93.44  ? 85  LEU C CD1   1 
ATOM   402  C CD2   . LEU A 1 85  ? 124.849 142.968 121.240 1.00 91.09  ? 85  LEU C CD2   1 
ATOM   403  N N     . ARG A 1 86  ? 126.022 138.224 121.250 1.00 97.30  ? 86  ARG C N     1 
ATOM   404  C CA    . ARG A 1 86  ? 127.325 137.632 121.533 1.00 99.15  ? 86  ARG C CA    1 
ATOM   405  C C     . ARG A 1 86  ? 127.184 136.362 122.365 1.00 105.94 ? 86  ARG C C     1 
ATOM   406  O O     . ARG A 1 86  ? 128.078 136.025 123.148 1.00 107.37 ? 86  ARG C O     1 
ATOM   407  C CB    . ARG A 1 86  ? 128.234 138.630 122.251 1.00 97.80  ? 86  ARG C CB    1 
ATOM   408  C CG    . ARG A 1 86  ? 128.559 139.867 121.431 1.00 93.99  ? 86  ARG C CG    1 
ATOM   409  C CD    . ARG A 1 86  ? 129.147 140.970 122.291 1.00 94.35  ? 86  ARG C CD    1 
ATOM   410  N NE    . ARG A 1 86  ? 129.158 142.251 121.594 1.00 95.00  ? 86  ARG C NE    1 
ATOM   411  C CZ    . ARG A 1 86  ? 129.362 143.423 122.179 1.00 93.40  ? 86  ARG C CZ    1 
ATOM   412  N NH1   . ARG A 1 86  ? 129.581 143.518 123.480 1.00 93.19  ? 86  ARG C NH1   1 
ATOM   413  N NH2   . ARG A 1 86  ? 129.345 144.528 121.440 1.00 95.58  ? 86  ARG C NH2   1 
ATOM   414  N N     . ALA A 1 87  ? 126.072 135.650 122.209 1.00 107.62 ? 87  ALA C N     1 
ATOM   415  C CA    . ALA A 1 87  ? 125.790 134.498 123.051 1.00 111.14 ? 87  ALA C CA    1 
ATOM   416  C C     . ALA A 1 87  ? 126.810 133.388 122.826 1.00 113.35 ? 87  ALA C C     1 
ATOM   417  O O     . ALA A 1 87  ? 127.325 133.197 121.722 1.00 115.98 ? 87  ALA C O     1 
ATOM   418  C CB    . ALA A 1 87  ? 124.384 133.969 122.773 1.00 107.80 ? 87  ALA C CB    1 
ATOM   419  N N     . SER A 1 88  ? 127.102 132.654 123.898 1.00 113.64 ? 88  SER C N     1 
ATOM   420  C CA    . SER A 1 88  ? 127.937 131.469 123.794 1.00 114.11 ? 88  SER C CA    1 
ATOM   421  C C     . SER A 1 88  ? 127.136 130.319 123.187 1.00 118.86 ? 88  SER C C     1 
ATOM   422  O O     . SER A 1 88  ? 125.918 130.398 123.008 1.00 118.72 ? 88  SER C O     1 
ATOM   423  C CB    . SER A 1 88  ? 128.480 131.071 125.165 1.00 109.86 ? 88  SER C CB    1 
ATOM   424  O OG    . SER A 1 88  ? 127.714 130.020 125.728 1.00 110.54 ? 88  SER C OG    1 
ATOM   425  N N     . GLU A 1 89  ? 127.838 129.230 122.869 1.00 122.94 ? 89  GLU C N     1 
ATOM   426  C CA    . GLU A 1 89  ? 127.181 128.108 122.206 1.00 123.91 ? 89  GLU C CA    1 
ATOM   427  C C     . GLU A 1 89  ? 126.058 127.537 123.064 1.00 122.09 ? 89  GLU C C     1 
ATOM   428  O O     . GLU A 1 89  ? 124.962 127.265 122.562 1.00 117.63 ? 89  GLU C O     1 
ATOM   429  C CB    . GLU A 1 89  ? 128.203 127.024 121.868 1.00 125.38 ? 89  GLU C CB    1 
ATOM   430  C CG    . GLU A 1 89  ? 129.059 127.350 120.656 1.00 125.46 ? 89  GLU C CG    1 
ATOM   431  C CD    . GLU A 1 89  ? 129.701 126.118 120.050 1.00 127.68 ? 89  GLU C CD    1 
ATOM   432  O OE1   . GLU A 1 89  ? 129.741 125.071 120.730 1.00 125.30 ? 89  GLU C OE1   1 
ATOM   433  O OE2   . GLU A 1 89  ? 130.156 126.196 118.890 1.00 129.00 ? 89  GLU C OE2   1 
ATOM   434  N N     . LYS A 1 90  ? 126.309 127.346 124.361 1.00 123.87 ? 90  LYS C N     1 
ATOM   435  C CA    . LYS A 1 90  ? 125.249 126.880 125.250 1.00 121.43 ? 90  LYS C CA    1 
ATOM   436  C C     . LYS A 1 90  ? 124.138 127.919 125.357 1.00 117.09 ? 90  LYS C C     1 
ATOM   437  O O     . LYS A 1 90  ? 122.948 127.590 125.274 1.00 114.85 ? 90  LYS C O     1 
ATOM   438  C CB    . LYS A 1 90  ? 125.828 126.560 126.627 1.00 121.02 ? 90  LYS C CB    1 
ATOM   439  C CG    . LYS A 1 90  ? 126.789 125.384 126.628 1.00 122.01 ? 90  LYS C CG    1 
ATOM   440  C CD    . LYS A 1 90  ? 127.371 125.138 128.008 1.00 123.77 ? 90  LYS C CD    1 
ATOM   441  C CE    . LYS A 1 90  ? 128.315 123.947 128.008 1.00 130.05 ? 90  LYS C CE    1 
ATOM   442  N NZ    . LYS A 1 90  ? 128.905 123.699 129.352 1.00 124.59 ? 90  LYS C NZ    1 
ATOM   443  N N     . LYS A 1 91  ? 124.513 129.188 125.530 1.00 113.56 ? 91  LYS C N     1 
ATOM   444  C CA    . LYS A 1 91  ? 123.518 130.253 125.541 1.00 111.40 ? 91  LYS C CA    1 
ATOM   445  C C     . LYS A 1 91  ? 122.820 130.350 124.192 1.00 113.84 ? 91  LYS C C     1 
ATOM   446  O O     . LYS A 1 91  ? 121.618 130.628 124.125 1.00 111.44 ? 91  LYS C O     1 
ATOM   447  C CB    . LYS A 1 91  ? 124.180 131.582 125.906 1.00 109.91 ? 91  LYS C CB    1 
ATOM   448  C CG    . LYS A 1 91  ? 123.219 132.759 125.980 1.00 108.00 ? 91  LYS C CG    1 
ATOM   449  C CD    . LYS A 1 91  ? 123.917 134.007 126.506 1.00 102.26 ? 91  LYS C CD    1 
ATOM   450  C CE    . LYS A 1 91  ? 123.180 135.280 126.115 1.00 99.27  ? 91  LYS C CE    1 
ATOM   451  N NZ    . LYS A 1 91  ? 124.118 136.414 125.894 1.00 98.05  ? 91  LYS C NZ    1 
ATOM   452  N N     . ARG A 1 92  ? 123.560 130.128 123.105 1.00 117.06 ? 92  ARG C N     1 
ATOM   453  C CA    . ARG A 1 92  ? 122.954 130.124 121.779 1.00 113.79 ? 92  ARG C CA    1 
ATOM   454  C C     . ARG A 1 92  ? 121.859 129.071 121.688 1.00 113.32 ? 92  ARG C C     1 
ATOM   455  O O     . ARG A 1 92  ? 120.750 129.347 121.216 1.00 110.24 ? 92  ARG C O     1 
ATOM   456  C CB    . ARG A 1 92  ? 124.026 129.869 120.721 1.00 110.94 ? 92  ARG C CB    1 
ATOM   457  C CG    . ARG A 1 92  ? 124.797 131.109 120.303 1.00 109.44 ? 92  ARG C CG    1 
ATOM   458  C CD    . ARG A 1 92  ? 123.972 132.035 119.425 1.00 111.18 ? 92  ARG C CD    1 
ATOM   459  N NE    . ARG A 1 92  ? 123.120 131.320 118.481 1.00 112.59 ? 92  ARG C NE    1 
ATOM   460  C CZ    . ARG A 1 92  ? 123.566 130.634 117.437 1.00 115.59 ? 92  ARG C CZ    1 
ATOM   461  N NH1   . ARG A 1 92  ? 124.858 130.547 117.167 1.00 120.15 ? 92  ARG C NH1   1 
ATOM   462  N NH2   . ARG A 1 92  ? 122.693 130.021 116.644 1.00 115.72 ? 92  ARG C NH2   1 
ATOM   463  N N     . GLU A 1 93  ? 122.159 127.850 122.137 1.00 116.63 ? 93  GLU C N     1 
ATOM   464  C CA    . GLU A 1 93  ? 121.164 126.785 122.101 1.00 118.21 ? 93  GLU C CA    1 
ATOM   465  C C     . GLU A 1 93  ? 119.977 127.117 122.993 1.00 116.77 ? 93  GLU C C     1 
ATOM   466  O O     . GLU A 1 93  ? 118.825 126.860 122.627 1.00 110.91 ? 93  GLU C O     1 
ATOM   467  C CB    . GLU A 1 93  ? 121.797 125.460 122.523 1.00 118.44 ? 93  GLU C CB    1 
ATOM   468  C CG    . GLU A 1 93  ? 120.846 124.275 122.450 1.00 119.48 ? 93  GLU C CG    1 
ATOM   469  C CD    . GLU A 1 93  ? 121.538 122.955 122.719 1.00 122.56 ? 93  GLU C CD    1 
ATOM   470  O OE1   . GLU A 1 93  ? 122.757 122.965 122.988 1.00 124.77 ? 93  GLU C OE1   1 
ATOM   471  O OE2   . GLU A 1 93  ? 120.863 121.905 122.659 1.00 123.41 ? 93  GLU C OE2   1 
ATOM   472  N N     . ARG A 1 94  ? 120.237 127.679 124.175 1.00 117.81 ? 94  ARG C N     1 
ATOM   473  C CA    . ARG A 1 94  ? 119.145 128.040 125.073 1.00 112.46 ? 94  ARG C CA    1 
ATOM   474  C C     . ARG A 1 94  ? 118.214 129.055 124.420 1.00 107.55 ? 94  ARG C C     1 
ATOM   475  O O     . ARG A 1 94  ? 116.988 128.892 124.433 1.00 102.35 ? 94  ARG C O     1 
ATOM   476  C CB    . ARG A 1 94  ? 119.707 128.590 126.385 1.00 113.05 ? 94  ARG C CB    1 
ATOM   477  C CG    . ARG A 1 94  ? 119.348 127.766 127.611 1.00 113.17 ? 94  ARG C CG    1 
ATOM   478  C CD    . ARG A 1 94  ? 119.931 128.378 128.874 1.00 111.89 ? 94  ARG C CD    1 
ATOM   479  N NE    . ARG A 1 94  ? 119.719 127.533 130.043 1.00 113.01 ? 94  ARG C NE    1 
ATOM   480  C CZ    . ARG A 1 94  ? 120.251 127.758 131.237 1.00 113.80 ? 94  ARG C CZ    1 
ATOM   481  N NH1   . ARG A 1 94  ? 121.038 128.799 131.460 1.00 109.22 ? 94  ARG C NH1   1 
ATOM   482  N NH2   . ARG A 1 94  ? 119.988 126.917 132.233 1.00 115.15 ? 94  ARG C NH2   1 
ATOM   483  N N     . GLU A 1 95  ? 118.784 130.113 123.835 1.00 109.47 ? 95  GLU C N     1 
ATOM   484  C CA    . GLU A 1 95  ? 117.961 131.131 123.190 1.00 106.77 ? 95  GLU C CA    1 
ATOM   485  C C     . GLU A 1 95  ? 117.210 130.560 121.993 1.00 105.26 ? 95  GLU C C     1 
ATOM   486  O O     . GLU A 1 95  ? 116.042 130.896 121.773 1.00 101.57 ? 95  GLU C O     1 
ATOM   487  C CB    . GLU A 1 95  ? 118.820 132.320 122.756 1.00 105.78 ? 95  GLU C CB    1 
ATOM   488  C CG    . GLU A 1 95  ? 119.609 132.993 123.874 1.00 106.21 ? 95  GLU C CG    1 
ATOM   489  C CD    . GLU A 1 95  ? 118.936 132.878 125.226 1.00 104.09 ? 95  GLU C CD    1 
ATOM   490  O OE1   . GLU A 1 95  ? 119.206 131.892 125.945 1.00 107.66 ? 95  GLU C OE1   1 
ATOM   491  O OE2   . GLU A 1 95  ? 118.134 133.771 125.569 1.00 95.53  ? 95  GLU C OE2   1 
ATOM   492  N N     . ASN A 1 96  ? 117.863 129.708 121.198 1.00 107.13 ? 96  ASN C N     1 
ATOM   493  C CA    . ASN A 1 96  ? 117.185 129.129 120.043 1.00 107.61 ? 96  ASN C CA    1 
ATOM   494  C C     . ASN A 1 96  ? 116.025 128.241 120.476 1.00 106.37 ? 96  ASN C C     1 
ATOM   495  O O     . ASN A 1 96  ? 114.948 128.273 119.868 1.00 102.74 ? 96  ASN C O     1 
ATOM   496  C CB    . ASN A 1 96  ? 118.178 128.343 119.188 1.00 110.10 ? 96  ASN C CB    1 
ATOM   497  C CG    . ASN A 1 96  ? 118.617 129.111 117.955 1.00 112.28 ? 96  ASN C CG    1 
ATOM   498  O OD1   . ASN A 1 96  ? 118.741 130.335 117.985 1.00 113.37 ? 96  ASN C OD1   1 
ATOM   499  N ND2   . ASN A 1 96  ? 118.859 128.393 116.863 1.00 109.61 ? 96  ASN C ND2   1 
ATOM   500  N N     . ALA A 1 97  ? 116.222 127.442 121.526 1.00 106.28 ? 97  ALA C N     1 
ATOM   501  C CA    . ALA A 1 97  ? 115.134 126.618 122.039 1.00 102.64 ? 97  ALA C CA    1 
ATOM   502  C C     . ALA A 1 97  ? 113.997 127.481 122.569 1.00 99.88  ? 97  ALA C C     1 
ATOM   503  O O     . ALA A 1 97  ? 112.819 127.180 122.341 1.00 96.25  ? 97  ALA C O     1 
ATOM   504  C CB    . ALA A 1 97  ? 115.653 125.684 123.132 1.00 103.83 ? 97  ALA C CB    1 
ATOM   505  N N     . LYS A 1 98  ? 114.329 128.561 123.280 1.00 100.06 ? 98  LYS C N     1 
ATOM   506  C CA    . LYS A 1 98  ? 113.295 129.456 123.786 1.00 96.67  ? 98  LYS C CA    1 
ATOM   507  C C     . LYS A 1 98  ? 112.491 130.057 122.641 1.00 95.00  ? 98  LYS C C     1 
ATOM   508  O O     . LYS A 1 98  ? 111.256 130.099 122.685 1.00 95.51  ? 98  LYS C O     1 
ATOM   509  C CB    . LYS A 1 98  ? 113.932 130.558 124.634 1.00 93.52  ? 98  LYS C CB    1 
ATOM   510  C CG    . LYS A 1 98  ? 112.936 131.449 125.359 1.00 87.62  ? 98  LYS C CG    1 
ATOM   511  C CD    . LYS A 1 98  ? 113.516 132.828 125.632 1.00 84.46  ? 98  LYS C CD    1 
ATOM   512  C CE    . LYS A 1 98  ? 113.378 133.742 124.425 1.00 85.93  ? 98  LYS C CE    1 
ATOM   513  N NZ    . LYS A 1 98  ? 114.497 134.721 124.334 1.00 84.79  ? 98  LYS C NZ    1 
ATOM   514  N N     . LYS A 1 99  ? 113.180 130.523 121.599 1.00 94.65  ? 99  LYS C N     1 
ATOM   515  C CA    . LYS A 1 99  ? 112.486 131.110 120.458 1.00 95.53  ? 99  LYS C CA    1 
ATOM   516  C C     . LYS A 1 99  ? 111.611 130.078 119.759 1.00 97.62  ? 99  LYS C C     1 
ATOM   517  O O     . LYS A 1 99  ? 110.483 130.381 119.354 1.00 94.57  ? 99  LYS C O     1 
ATOM   518  C CB    . LYS A 1 99  ? 113.503 131.711 119.485 1.00 96.58  ? 99  LYS C CB    1 
ATOM   519  C CG    . LYS A 1 99  ? 112.994 131.921 118.060 1.00 98.24  ? 99  LYS C CG    1 
ATOM   520  C CD    . LYS A 1 99  ? 111.760 132.811 118.009 1.00 96.20  ? 99  LYS C CD    1 
ATOM   521  C CE    . LYS A 1 99  ? 110.816 132.387 116.897 1.00 95.87  ? 99  LYS C CE    1 
ATOM   522  N NZ    . LYS A 1 99  ? 109.925 131.271 117.318 1.00 97.22  ? 99  LYS C NZ    1 
ATOM   523  N N     . SER A 1 100 ? 112.116 128.852 119.604 1.00 100.96 ? 100 SER C N     1 
ATOM   524  C CA    . SER A 1 100 ? 111.360 127.825 118.897 1.00 99.14  ? 100 SER C CA    1 
ATOM   525  C C     . SER A 1 100 ? 110.221 127.273 119.744 1.00 98.97  ? 100 SER C C     1 
ATOM   526  O O     . SER A 1 100 ? 109.214 126.811 119.196 1.00 97.49  ? 100 SER C O     1 
ATOM   527  C CB    . SER A 1 100 ? 112.294 126.695 118.468 1.00 99.84  ? 100 SER C CB    1 
ATOM   528  O OG    . SER A 1 100 ? 112.650 125.885 119.574 1.00 100.84 ? 100 SER C OG    1 
ATOM   529  N N     . ARG A 1 101 ? 110.354 127.310 121.067 1.00 98.40  ? 101 ARG C N     1 
ATOM   530  C CA    . ARG A 1 101 ? 109.324 126.750 121.931 1.00 94.30  ? 101 ARG C CA    1 
ATOM   531  C C     . ARG A 1 101 ? 108.011 127.504 121.756 1.00 89.82  ? 101 ARG C C     1 
ATOM   532  O O     . ARG A 1 101 ? 107.989 128.712 121.505 1.00 92.41  ? 101 ARG C O     1 
ATOM   533  C CB    . ARG A 1 101 ? 109.767 126.803 123.393 1.00 95.14  ? 101 ARG C CB    1 
ATOM   534  C CG    . ARG A 1 101 ? 110.308 125.485 123.921 1.00 95.17  ? 101 ARG C CG    1 
ATOM   535  C CD    . ARG A 1 101 ? 110.934 125.655 125.294 1.00 96.09  ? 101 ARG C CD    1 
ATOM   536  N NE    . ARG A 1 101 ? 112.306 126.141 125.211 1.00 96.24  ? 101 ARG C NE    1 
ATOM   537  C CZ    . ARG A 1 101 ? 112.966 126.699 126.216 1.00 96.34  ? 101 ARG C CZ    1 
ATOM   538  N NH1   . ARG A 1 101 ? 112.410 126.859 127.406 1.00 93.50  ? 101 ARG C NH1   1 
ATOM   539  N NH2   . ARG A 1 101 ? 114.216 127.108 126.023 1.00 99.38  ? 101 ARG C NH2   1 
ATOM   540  N N     . LYS A 1 102 ? 106.906 126.775 121.884 1.00 86.01  ? 102 LYS C N     1 
ATOM   541  C CA    . LYS A 1 102 ? 105.594 127.384 121.721 1.00 88.71  ? 102 LYS C CA    1 
ATOM   542  C C     . LYS A 1 102 ? 105.368 128.454 122.781 1.00 91.82  ? 102 LYS C C     1 
ATOM   543  O O     . LYS A 1 102 ? 105.674 128.260 123.961 1.00 89.37  ? 102 LYS C O     1 
ATOM   544  C CB    . LYS A 1 102 ? 104.499 126.321 121.808 1.00 88.03  ? 102 LYS C CB    1 
ATOM   545  C CG    . LYS A 1 102 ? 103.096 126.868 121.588 1.00 89.39  ? 102 LYS C CG    1 
ATOM   546  C CD    . LYS A 1 102 ? 102.051 125.768 121.641 1.00 91.47  ? 102 LYS C CD    1 
ATOM   547  C CE    . LYS A 1 102 ? 100.658 126.320 121.384 1.00 88.54  ? 102 LYS C CE    1 
ATOM   548  N NZ    . LYS A 1 102 ? 99.615  125.258 121.430 1.00 88.15  ? 102 LYS C NZ    1 
ATOM   549  N N     . ALA A 1 103 ? 104.823 129.590 122.352 1.00 89.71  ? 103 ALA C N     1 
ATOM   550  C CA    . ALA A 1 103 ? 104.570 130.690 123.262 1.00 84.98  ? 103 ALA C CA    1 
ATOM   551  C C     . ALA A 1 103 ? 103.376 130.375 124.160 1.00 82.28  ? 103 ALA C C     1 
ATOM   552  O O     . ALA A 1 103 ? 102.548 129.523 123.833 1.00 86.20  ? 103 ALA C O     1 
ATOM   553  C CB    . ALA A 1 103 ? 104.313 131.975 122.482 1.00 81.47  ? 103 ALA C CB    1 
ATOM   554  N N     . PRO A 1 104 ? 103.267 131.053 125.302 1.00 78.37  ? 104 PRO C N     1 
ATOM   555  C CA    . PRO A 1 104 ? 102.120 130.818 126.185 1.00 80.32  ? 104 PRO C CA    1 
ATOM   556  C C     . PRO A 1 104 ? 100.802 131.052 125.463 1.00 82.77  ? 104 PRO C C     1 
ATOM   557  O O     . PRO A 1 104 ? 100.676 131.954 124.633 1.00 82.76  ? 104 PRO C O     1 
ATOM   558  C CB    . PRO A 1 104 ? 102.331 131.831 127.315 1.00 74.95  ? 104 PRO C CB    1 
ATOM   559  C CG    . PRO A 1 104 ? 103.794 132.056 127.345 1.00 73.03  ? 104 PRO C CG    1 
ATOM   560  C CD    . PRO A 1 104 ? 104.267 131.939 125.925 1.00 76.67  ? 104 PRO C CD    1 
ATOM   561  N N     . GLU A 1 105 ? 99.816  130.224 125.790 1.00 83.59  ? 105 GLU C N     1 
ATOM   562  C CA    . GLU A 1 105 ? 98.507  130.256 125.157 1.00 81.91  ? 105 GLU C CA    1 
ATOM   563  C C     . GLU A 1 105 ? 97.458  130.748 126.144 1.00 86.78  ? 105 GLU C C     1 
ATOM   564  O O     . GLU A 1 105 ? 97.606  130.614 127.361 1.00 91.07  ? 105 GLU C O     1 
ATOM   565  C CB    . GLU A 1 105 ? 98.122  128.870 124.621 1.00 85.10  ? 105 GLU C CB    1 
ATOM   566  C CG    . GLU A 1 105 ? 97.761  127.836 125.688 1.00 87.48  ? 105 GLU C CG    1 
ATOM   567  C CD    . GLU A 1 105 ? 98.966  127.345 126.465 1.00 87.37  ? 105 GLU C CD    1 
ATOM   568  O OE1   . GLU A 1 105 ? 100.024 128.004 126.403 1.00 83.11  ? 105 GLU C OE1   1 
ATOM   569  O OE2   . GLU A 1 105 ? 98.854  126.303 127.143 1.00 91.83  ? 105 GLU C OE2   1 
ATOM   570  N N     . ALA A 1 106 ? 96.386  131.319 125.599 1.00 84.17  ? 106 ALA C N     1 
ATOM   571  C CA    . ALA A 1 106 ? 95.320  131.849 126.437 1.00 86.09  ? 106 ALA C CA    1 
ATOM   572  C C     . ALA A 1 106 ? 94.775  130.761 127.351 1.00 87.11  ? 106 ALA C C     1 
ATOM   573  O O     . ALA A 1 106 ? 94.589  129.613 126.939 1.00 84.62  ? 106 ALA C O     1 
ATOM   574  C CB    . ALA A 1 106 ? 94.199  132.422 125.571 1.00 80.53  ? 106 ALA C CB    1 
ATOM   575  N N     . GLY A 1 107 ? 94.519  131.130 128.604 1.00 84.99  ? 107 GLY C N     1 
ATOM   576  C CA    . GLY A 1 107 ? 94.083  130.188 129.609 1.00 84.79  ? 107 GLY C CA    1 
ATOM   577  C C     . GLY A 1 107 ? 95.191  129.597 130.452 1.00 86.49  ? 107 GLY C C     1 
ATOM   578  O O     . GLY A 1 107 ? 94.902  128.790 131.345 1.00 90.55  ? 107 GLY C O     1 
ATOM   579  N N     . MET A 1 108 ? 96.444  129.963 130.200 1.00 84.57  ? 108 MET C N     1 
ATOM   580  C CA    . MET A 1 108 ? 97.544  129.480 131.021 1.00 85.86  ? 108 MET C CA    1 
ATOM   581  C C     . MET A 1 108 ? 97.421  130.026 132.439 1.00 85.36  ? 108 MET C C     1 
ATOM   582  O O     . MET A 1 108 ? 96.909  131.125 132.666 1.00 81.67  ? 108 MET C O     1 
ATOM   583  C CB    . MET A 1 108 ? 98.886  129.891 130.411 1.00 83.63  ? 108 MET C CB    1 
ATOM   584  C CG    . MET A 1 108 ? 100.075 129.825 131.370 1.00 85.53  ? 108 MET C CG    1 
ATOM   585  S SD    . MET A 1 108 ? 101.620 130.371 130.620 1.00 95.14  ? 108 MET C SD    1 
ATOM   586  C CE    . MET A 1 108 ? 102.804 129.345 131.486 1.00 88.09  ? 108 MET C CE    1 
ATOM   587  N N     . ARG A 1 109 ? 97.897  129.239 133.400 1.00 83.15  ? 109 ARG C N     1 
ATOM   588  C CA    . ARG A 1 109 ? 97.913  129.633 134.802 1.00 81.76  ? 109 ARG C CA    1 
ATOM   589  C C     . ARG A 1 109 ? 99.311  130.119 135.158 1.00 80.96  ? 109 ARG C C     1 
ATOM   590  O O     . ARG A 1 109 ? 100.276 129.352 135.082 1.00 79.91  ? 109 ARG C O     1 
ATOM   591  C CB    . ARG A 1 109 ? 97.507  128.467 135.704 1.00 83.83  ? 109 ARG C CB    1 
ATOM   592  C CG    . ARG A 1 109 ? 96.010  128.346 135.940 1.00 85.03  ? 109 ARG C CG    1 
ATOM   593  C CD    . ARG A 1 109 ? 95.239  128.261 134.633 1.00 84.36  ? 109 ARG C CD    1 
ATOM   594  N NE    . ARG A 1 109 ? 93.820  128.004 134.849 1.00 83.19  ? 109 ARG C NE    1 
ATOM   595  C CZ    . ARG A 1 109 ? 92.998  127.512 133.932 1.00 84.14  ? 109 ARG C CZ    1 
ATOM   596  N NH1   . ARG A 1 109 ? 93.417  127.219 132.711 1.00 82.62  ? 109 ARG C NH1   1 
ATOM   597  N NH2   . ARG A 1 109 ? 91.721  127.310 134.247 1.00 86.28  ? 109 ARG C NH2   1 
ATOM   598  N N     . VAL A 1 110 ? 99.416  131.387 135.543 1.00 79.27  ? 110 VAL C N     1 
ATOM   599  C CA    . VAL A 1 110 ? 100.675 131.991 135.964 1.00 77.22  ? 110 VAL C CA    1 
ATOM   600  C C     . VAL A 1 110 ? 100.563 132.232 137.462 1.00 76.08  ? 110 VAL C C     1 
ATOM   601  O O     . VAL A 1 110 ? 99.732  133.025 137.916 1.00 75.19  ? 110 VAL C O     1 
ATOM   602  C CB    . VAL A 1 110 ? 100.976 133.288 135.208 1.00 70.79  ? 110 VAL C CB    1 
ATOM   603  C CG1   . VAL A 1 110 ? 102.235 133.934 135.753 1.00 69.62  ? 110 VAL C CG1   1 
ATOM   604  C CG2   . VAL A 1 110 ? 101.120 133.013 133.725 1.00 70.99  ? 110 VAL C CG2   1 
ATOM   605  N N     . GLY A 1 111 ? 101.388 131.554 138.230 1.00 75.31  ? 111 GLY C N     1 
ATOM   606  C CA    . GLY A 1 111 ? 101.333 131.656 139.684 1.00 78.30  ? 111 GLY C CA    1 
ATOM   607  C C     . GLY A 1 111 ? 100.225 130.781 140.253 1.00 84.57  ? 111 GLY C C     1 
ATOM   608  O O     . GLY A 1 111 ? 100.251 129.565 140.083 1.00 77.57  ? 111 GLY C O     1 
ATOM   609  N N     . ARG A 1 112 ? 99.261  131.406 140.915 1.00 92.93  ? 112 ARG C N     1 
ATOM   610  C CA    . ARG A 1 112 ? 98.170  130.679 141.555 1.00 94.62  ? 112 ARG C CA    1 
ATOM   611  C C     . ARG A 1 112 ? 96.791  131.169 141.141 1.00 93.81  ? 112 ARG C C     1 
ATOM   612  O O     . ARG A 1 112 ? 95.879  130.350 140.998 1.00 96.41  ? 112 ARG C O     1 
ATOM   613  C CB    . ARG A 1 112 ? 98.323  130.780 143.083 1.00 97.77  ? 112 ARG C CB    1 
ATOM   614  C CG    . ARG A 1 112 ? 97.010  130.793 143.863 1.00 96.90  ? 112 ARG C CG    1 
ATOM   615  C CD    . ARG A 1 112 ? 97.245  130.621 145.358 1.00 102.18 ? 112 ARG C CD    1 
ATOM   616  N NE    . ARG A 1 112 ? 98.510  131.209 145.786 1.00 108.43 ? 112 ARG C NE    1 
ATOM   617  C CZ    . ARG A 1 112 ? 99.649  130.541 145.920 1.00 113.12 ? 112 ARG C CZ    1 
ATOM   618  N NH1   . ARG A 1 112 ? 99.728  129.244 145.667 1.00 110.89 ? 112 ARG C NH1   1 
ATOM   619  N NH2   . ARG A 1 112 ? 100.740 131.193 146.312 1.00 114.98 ? 112 ARG C NH2   1 
ATOM   620  N N     . SER A 1 113 ? 96.611  132.479 140.942 1.00 88.83  ? 113 SER C N     1 
ATOM   621  C CA    . SER A 1 113 ? 95.286  133.025 140.673 1.00 82.80  ? 113 SER C CA    1 
ATOM   622  C C     . SER A 1 113 ? 95.306  134.030 139.527 1.00 75.51  ? 113 SER C C     1 
ATOM   623  O O     . SER A 1 113 ? 94.492  134.960 139.502 1.00 74.81  ? 113 SER C O     1 
ATOM   624  C CB    . SER A 1 113 ? 94.703  133.686 141.922 1.00 81.96  ? 113 SER C CB    1 
ATOM   625  O OG    . SER A 1 113 ? 93.842  134.755 141.573 1.00 82.35  ? 113 SER C OG    1 
ATOM   626  N N     . LEU A 1 114 ? 96.220  133.864 138.575 1.00 69.74  ? 114 LEU C N     1 
ATOM   627  C CA    . LEU A 1 114 ? 96.278  134.697 137.383 1.00 69.03  ? 114 LEU C CA    1 
ATOM   628  C C     . LEU A 1 114 ? 96.141  133.806 136.159 1.00 74.92  ? 114 LEU C C     1 
ATOM   629  O O     . LEU A 1 114 ? 96.879  132.825 136.017 1.00 77.67  ? 114 LEU C O     1 
ATOM   630  C CB    . LEU A 1 114 ? 97.587  135.489 137.326 1.00 67.69  ? 114 LEU C CB    1 
ATOM   631  C CG    . LEU A 1 114 ? 97.769  136.556 138.406 1.00 61.96  ? 114 LEU C CG    1 
ATOM   632  C CD1   . LEU A 1 114 ? 99.233  136.923 138.545 1.00 59.31  ? 114 LEU C CD1   1 
ATOM   633  C CD2   . LEU A 1 114 ? 96.940  137.787 138.092 1.00 58.24  ? 114 LEU C CD2   1 
ATOM   634  N N     . ILE A 1 115 ? 95.202  134.146 135.280 1.00 75.89  ? 115 ILE C N     1 
ATOM   635  C CA    . ILE A 1 115 ? 94.921  133.370 134.078 1.00 77.42  ? 115 ILE C CA    1 
ATOM   636  C C     . ILE A 1 115 ? 95.108  134.274 132.868 1.00 80.51  ? 115 ILE C C     1 
ATOM   637  O O     . ILE A 1 115 ? 94.512  135.355 132.797 1.00 82.64  ? 115 ILE C O     1 
ATOM   638  C CB    . ILE A 1 115 ? 93.500  132.779 134.105 1.00 80.84  ? 115 ILE C CB    1 
ATOM   639  C CG1   . ILE A 1 115 ? 93.416  131.647 135.129 1.00 82.82  ? 115 ILE C CG1   1 
ATOM   640  C CG2   . ILE A 1 115 ? 93.105  132.270 132.726 1.00 82.03  ? 115 ILE C CG2   1 
ATOM   641  C CD1   . ILE A 1 115 ? 92.163  131.684 135.976 1.00 79.25  ? 115 ILE C CD1   1 
ATOM   642  N N     . LEU A 1 116 ? 95.931  133.831 131.921 1.00 78.27  ? 116 LEU C N     1 
ATOM   643  C CA    . LEU A 1 116 ? 96.164  134.600 130.708 1.00 74.43  ? 116 LEU C CA    1 
ATOM   644  C C     . LEU A 1 116 ? 94.920  134.604 129.829 1.00 74.73  ? 116 LEU C C     1 
ATOM   645  O O     . LEU A 1 116 ? 94.167  133.629 129.773 1.00 76.46  ? 116 LEU C O     1 
ATOM   646  C CB    . LEU A 1 116 ? 97.345  134.024 129.929 1.00 74.64  ? 116 LEU C CB    1 
ATOM   647  C CG    . LEU A 1 116 ? 98.610  133.747 130.739 1.00 74.41  ? 116 LEU C CG    1 
ATOM   648  C CD1   . LEU A 1 116 ? 99.776  133.446 129.814 1.00 75.49  ? 116 LEU C CD1   1 
ATOM   649  C CD2   . LEU A 1 116 ? 98.934  134.921 131.645 1.00 75.06  ? 116 LEU C CD2   1 
ATOM   650  N N     . THR A 1 117 ? 94.712  135.716 129.136 1.00 74.83  ? 117 THR C N     1 
ATOM   651  C CA    . THR A 1 117 ? 93.581  135.888 128.239 1.00 79.93  ? 117 THR C CA    1 
ATOM   652  C C     . THR A 1 117 ? 94.058  135.857 126.790 1.00 86.12  ? 117 THR C C     1 
ATOM   653  O O     . THR A 1 117 ? 95.247  135.695 126.502 1.00 85.76  ? 117 THR C O     1 
ATOM   654  C CB    . THR A 1 117 ? 92.845  137.195 128.540 1.00 79.35  ? 117 THR C CB    1 
ATOM   655  O OG1   . THR A 1 117 ? 93.420  138.259 127.772 1.00 79.27  ? 117 THR C OG1   1 
ATOM   656  C CG2   . THR A 1 117 ? 92.938  137.533 130.017 1.00 76.27  ? 117 THR C CG2   1 
ATOM   657  N N     . SER A 1 118 ? 93.106  136.014 125.870 1.00 89.67  ? 118 SER C N     1 
ATOM   658  C CA    . SER A 1 118 ? 93.421  136.023 124.448 1.00 86.82  ? 118 SER C CA    1 
ATOM   659  C C     . SER A 1 118 ? 94.070  137.325 123.998 1.00 83.45  ? 118 SER C C     1 
ATOM   660  O O     . SER A 1 118 ? 94.703  137.352 122.938 1.00 80.66  ? 118 SER C O     1 
ATOM   661  C CB    . SER A 1 118 ? 92.152  135.783 123.630 1.00 87.67  ? 118 SER C CB    1 
ATOM   662  O OG    . SER A 1 118 ? 91.312  136.925 123.655 1.00 85.60  ? 118 SER C OG    1 
ATOM   663  N N     . ARG A 1 119 ? 93.925  138.399 124.772 1.00 83.38  ? 119 ARG C N     1 
ATOM   664  C CA    . ARG A 1 119 ? 94.483  139.689 124.395 1.00 84.71  ? 119 ARG C CA    1 
ATOM   665  C C     . ARG A 1 119 ? 95.966  139.815 124.711 1.00 79.57  ? 119 ARG C C     1 
ATOM   666  O O     . ARG A 1 119 ? 96.584  140.805 124.308 1.00 80.35  ? 119 ARG C O     1 
ATOM   667  C CB    . ARG A 1 119 ? 93.720  140.815 125.099 1.00 85.06  ? 119 ARG C CB    1 
ATOM   668  C CG    . ARG A 1 119 ? 92.492  141.297 124.345 1.00 85.36  ? 119 ARG C CG    1 
ATOM   669  C CD    . ARG A 1 119 ? 91.852  142.489 125.033 1.00 85.88  ? 119 ARG C CD    1 
ATOM   670  N NE    . ARG A 1 119 ? 91.183  142.104 126.270 1.00 92.64  ? 119 ARG C NE    1 
ATOM   671  C CZ    . ARG A 1 119 ? 90.888  142.939 127.257 1.00 97.52  ? 119 ARG C CZ    1 
ATOM   672  N NH1   . ARG A 1 119 ? 91.174  144.229 127.183 1.00 96.14  ? 119 ARG C NH1   1 
ATOM   673  N NH2   . ARG A 1 119 ? 90.286  142.469 128.346 1.00 98.12  ? 119 ARG C NH2   1 
ATOM   674  N N     . TRP A 1 120 ? 96.555  138.847 125.414 1.00 73.08  ? 120 TRP C N     1 
ATOM   675  C CA    . TRP A 1 120 ? 97.951  138.988 125.810 1.00 71.49  ? 120 TRP C CA    1 
ATOM   676  C C     . TRP A 1 120 ? 98.884  138.939 124.609 1.00 69.27  ? 120 TRP C C     1 
ATOM   677  O O     . TRP A 1 120 ? 99.930  139.596 124.617 1.00 65.75  ? 120 TRP C O     1 
ATOM   678  C CB    . TRP A 1 120 ? 98.317  137.915 126.836 1.00 74.73  ? 120 TRP C CB    1 
ATOM   679  C CG    . TRP A 1 120 ? 98.991  136.704 126.283 1.00 73.09  ? 120 TRP C CG    1 
ATOM   680  C CD1   . TRP A 1 120 ? 98.402  135.528 125.930 1.00 73.39  ? 120 TRP C CD1   1 
ATOM   681  C CD2   . TRP A 1 120 ? 100.392 136.541 126.039 1.00 70.94  ? 120 TRP C CD2   1 
ATOM   682  N NE1   . TRP A 1 120 ? 99.347  134.643 125.475 1.00 73.26  ? 120 TRP C NE1   1 
ATOM   683  C CE2   . TRP A 1 120 ? 100.578 135.242 125.531 1.00 70.40  ? 120 TRP C CE2   1 
ATOM   684  C CE3   . TRP A 1 120 ? 101.506 137.368 126.195 1.00 70.69  ? 120 TRP C CE3   1 
ATOM   685  C CZ2   . TRP A 1 120 ? 101.831 134.753 125.179 1.00 73.57  ? 120 TRP C CZ2   1 
ATOM   686  C CZ3   . TRP A 1 120 ? 102.748 136.880 125.845 1.00 68.12  ? 120 TRP C CZ3   1 
ATOM   687  C CH2   . TRP A 1 120 ? 102.902 135.586 125.343 1.00 69.71  ? 120 TRP C CH2   1 
ATOM   688  N N     . THR A 1 121 ? 98.530  138.178 123.572 1.00 72.00  ? 121 THR C N     1 
ATOM   689  C CA    . THR A 1 121 ? 99.350  138.160 122.364 1.00 70.96  ? 121 THR C CA    1 
ATOM   690  C C     . THR A 1 121 ? 99.367  139.526 121.690 1.00 68.51  ? 121 THR C C     1 
ATOM   691  O O     . THR A 1 121 ? 100.424 140.000 121.258 1.00 69.34  ? 121 THR C O     1 
ATOM   692  C CB    . THR A 1 121 ? 98.836  137.099 121.394 1.00 71.27  ? 121 THR C CB    1 
ATOM   693  O OG1   . THR A 1 121 ? 99.048  135.795 121.949 1.00 73.84  ? 121 THR C OG1   1 
ATOM   694  C CG2   . THR A 1 121 ? 99.556  137.203 120.059 1.00 71.44  ? 121 THR C CG2   1 
ATOM   695  N N     . GLU A 1 122 ? 98.205  140.175 121.589 1.00 68.59  ? 122 GLU C N     1 
ATOM   696  C CA    . GLU A 1 122 ? 98.151  141.495 120.969 1.00 69.92  ? 122 GLU C CA    1 
ATOM   697  C C     . GLU A 1 122 ? 98.993  142.502 121.742 1.00 68.72  ? 122 GLU C C     1 
ATOM   698  O O     . GLU A 1 122 ? 99.739  143.289 121.145 1.00 68.52  ? 122 GLU C O     1 
ATOM   699  C CB    . GLU A 1 122 ? 96.700  141.968 120.879 1.00 72.33  ? 122 GLU C CB    1 
ATOM   700  C CG    . GLU A 1 122 ? 96.525  143.331 120.232 1.00 76.05  ? 122 GLU C CG    1 
ATOM   701  C CD    . GLU A 1 122 ? 95.072  143.748 120.138 1.00 81.22  ? 122 GLU C CD    1 
ATOM   702  O OE1   . GLU A 1 122 ? 94.203  142.987 120.613 1.00 86.52  ? 122 GLU C OE1   1 
ATOM   703  O OE2   . GLU A 1 122 ? 94.797  144.835 119.591 1.00 74.17  ? 122 GLU C OE2   1 
ATOM   704  N N     . TYR A 1 123 ? 98.881  142.499 123.072 1.00 67.58  ? 123 TYR C N     1 
ATOM   705  C CA    . TYR A 1 123 ? 99.680  143.414 123.879 1.00 65.36  ? 123 TYR C CA    1 
ATOM   706  C C     . TYR A 1 123 ? 101.166 143.119 123.731 1.00 62.47  ? 123 TYR C C     1 
ATOM   707  O O     . TYR A 1 123 ? 101.974 144.039 123.569 1.00 59.66  ? 123 TYR C O     1 
ATOM   708  C CB    . TYR A 1 123 ? 99.263  143.324 125.346 1.00 65.24  ? 123 TYR C CB    1 
ATOM   709  C CG    . TYR A 1 123 ? 100.290 143.884 126.302 1.00 59.99  ? 123 TYR C CG    1 
ATOM   710  C CD1   . TYR A 1 123 ? 100.370 145.246 126.545 1.00 57.58  ? 123 TYR C CD1   1 
ATOM   711  C CD2   . TYR A 1 123 ? 101.184 143.051 126.958 1.00 54.54  ? 123 TYR C CD2   1 
ATOM   712  C CE1   . TYR A 1 123 ? 101.307 145.761 127.413 1.00 55.38  ? 123 TYR C CE1   1 
ATOM   713  C CE2   . TYR A 1 123 ? 102.124 143.557 127.827 1.00 46.00  ? 123 TYR C CE2   1 
ATOM   714  C CZ    . TYR A 1 123 ? 102.181 144.911 128.052 1.00 51.27  ? 123 TYR C CZ    1 
ATOM   715  O OH    . TYR A 1 123 ? 103.120 145.417 128.919 1.00 51.41  ? 123 TYR C OH    1 
ATOM   716  N N     . CYS A 1 124 ? 101.548 141.842 123.778 1.00 63.38  ? 124 CYS C N     1 
ATOM   717  C CA    . CYS A 1 124 ? 102.956 141.495 123.628 1.00 59.23  ? 124 CYS C CA    1 
ATOM   718  C C     . CYS A 1 124 ? 103.487 141.944 122.276 1.00 63.99  ? 124 CYS C C     1 
ATOM   719  O O     . CYS A 1 124 ? 104.642 142.368 122.164 1.00 67.07  ? 124 CYS C O     1 
ATOM   720  C CB    . CYS A 1 124 ? 103.148 139.990 123.803 1.00 63.31  ? 124 CYS C CB    1 
ATOM   721  S SG    . CYS A 1 124 ? 104.746 139.381 123.218 1.00 65.44  ? 124 CYS C SG    1 
ATOM   722  N N     . ALA A 1 125 ? 102.662 141.853 121.233 1.00 66.38  ? 125 ALA C N     1 
ATOM   723  C CA    . ALA A 1 125 ? 103.116 142.244 119.905 1.00 64.87  ? 125 ALA C CA    1 
ATOM   724  C C     . ALA A 1 125 ? 103.235 143.757 119.775 1.00 66.04  ? 125 ALA C C     1 
ATOM   725  O O     . ALA A 1 125 ? 104.214 144.260 119.211 1.00 65.15  ? 125 ALA C O     1 
ATOM   726  C CB    . ALA A 1 125 ? 102.166 141.692 118.844 1.00 65.06  ? 125 ALA C CB    1 
ATOM   727  N N     . THR A 1 126 ? 102.259 144.502 120.294 1.00 66.68  ? 126 THR C N     1 
ATOM   728  C CA    . THR A 1 126 ? 102.184 145.931 120.011 1.00 64.94  ? 126 THR C CA    1 
ATOM   729  C C     . THR A 1 126 ? 102.944 146.798 121.008 1.00 67.31  ? 126 THR C C     1 
ATOM   730  O O     . THR A 1 126 ? 103.459 147.853 120.621 1.00 63.21  ? 126 THR C O     1 
ATOM   731  C CB    . THR A 1 126 ? 100.721 146.384 119.973 1.00 66.41  ? 126 THR C CB    1 
ATOM   732  O OG1   . THR A 1 126 ? 100.627 147.645 119.298 1.00 65.95  ? 126 THR C OG1   1 
ATOM   733  C CG2   . THR A 1 126 ? 100.157 146.523 121.379 1.00 67.02  ? 126 THR C CG2   1 
ATOM   734  N N     . CYS A 1 127 ? 103.035 146.390 122.277 1.00 66.19  ? 127 CYS C N     1 
ATOM   735  C CA    . CYS A 1 127 ? 103.588 147.244 123.319 1.00 60.71  ? 127 CYS C CA    1 
ATOM   736  C C     . CYS A 1 127 ? 105.004 146.882 123.741 1.00 54.39  ? 127 CYS C C     1 
ATOM   737  O O     . CYS A 1 127 ? 105.712 147.752 124.254 1.00 55.13  ? 127 CYS C O     1 
ATOM   738  C CB    . CYS A 1 127 ? 102.685 147.219 124.560 1.00 61.55  ? 127 CYS C CB    1 
ATOM   739  S SG    . CYS A 1 127 ? 101.253 148.317 124.450 1.00 72.75  ? 127 CYS C SG    1 
ATOM   740  N N     . VAL A 1 128 ? 105.432 145.639 123.553 1.00 51.74  ? 128 VAL C N     1 
ATOM   741  C CA    . VAL A 1 128 ? 106.803 145.252 123.875 1.00 51.53  ? 128 VAL C CA    1 
ATOM   742  C C     . VAL A 1 128 ? 107.715 145.745 122.757 1.00 57.60  ? 128 VAL C C     1 
ATOM   743  O O     . VAL A 1 128 ? 107.521 145.356 121.596 1.00 63.49  ? 128 VAL C O     1 
ATOM   744  C CB    . VAL A 1 128 ? 106.932 143.732 124.053 1.00 50.28  ? 128 VAL C CB    1 
ATOM   745  C CG1   . VAL A 1 128 ? 108.387 143.341 124.241 1.00 49.38  ? 128 VAL C CG1   1 
ATOM   746  C CG2   . VAL A 1 128 ? 106.100 143.266 125.226 1.00 56.20  ? 128 VAL C CG2   1 
ATOM   747  N N     . PRO A 1 129 ? 108.709 146.587 123.038 1.00 59.00  ? 129 PRO C N     1 
ATOM   748  C CA    . PRO A 1 129 ? 109.634 146.995 121.976 1.00 61.83  ? 129 PRO C CA    1 
ATOM   749  C C     . PRO A 1 129 ? 110.337 145.787 121.377 1.00 66.05  ? 129 PRO C C     1 
ATOM   750  O O     . PRO A 1 129 ? 110.653 144.821 122.074 1.00 65.78  ? 129 PRO C O     1 
ATOM   751  C CB    . PRO A 1 129 ? 110.622 147.923 122.692 1.00 62.15  ? 129 PRO C CB    1 
ATOM   752  C CG    . PRO A 1 129 ? 109.942 148.353 123.930 1.00 58.28  ? 129 PRO C CG    1 
ATOM   753  C CD    . PRO A 1 129 ? 108.988 147.271 124.311 1.00 58.99  ? 129 PRO C CD    1 
ATOM   754  N N     . ALA A 1 130 ? 110.580 145.848 120.071 1.00 64.65  ? 130 ALA C N     1 
ATOM   755  C CA    . ALA A 1 130 ? 111.274 144.758 119.401 1.00 64.16  ? 130 ALA C CA    1 
ATOM   756  C C     . ALA A 1 130 ? 112.656 144.573 120.010 1.00 68.56  ? 130 ALA C C     1 
ATOM   757  O O     . ALA A 1 130 ? 113.305 145.538 120.419 1.00 75.90  ? 130 ALA C O     1 
ATOM   758  C CB    . ALA A 1 130 ? 111.389 145.039 117.904 1.00 70.45  ? 130 ALA C CB    1 
ATOM   759  N N     . LEU A 1 131 ? 113.103 143.320 120.073 1.00 66.55  ? 131 LEU C N     1 
ATOM   760  C CA    . LEU A 1 131 ? 114.357 143.004 120.745 1.00 69.55  ? 131 LEU C CA    1 
ATOM   761  C C     . LEU A 1 131 ? 115.480 143.888 120.223 1.00 73.42  ? 131 LEU C C     1 
ATOM   762  O O     . LEU A 1 131 ? 115.653 144.048 119.013 1.00 82.42  ? 131 LEU C O     1 
ATOM   763  C CB    . LEU A 1 131 ? 114.704 141.528 120.539 1.00 70.50  ? 131 LEU C CB    1 
ATOM   764  C CG    . LEU A 1 131 ? 116.018 141.052 121.165 1.00 74.36  ? 131 LEU C CG    1 
ATOM   765  C CD1   . LEU A 1 131 ? 116.058 141.350 122.652 1.00 76.57  ? 131 LEU C CD1   1 
ATOM   766  C CD2   . LEU A 1 131 ? 116.221 139.569 120.922 1.00 77.77  ? 131 LEU C CD2   1 
ATOM   767  N N     . GLY A 1 132 ? 116.240 144.467 121.150 1.00 70.54  ? 132 GLY C N     1 
ATOM   768  C CA    . GLY A 1 132 ? 117.340 145.339 120.805 1.00 74.71  ? 132 GLY C CA    1 
ATOM   769  C C     . GLY A 1 132 ? 116.969 146.785 120.565 1.00 79.15  ? 132 GLY C C     1 
ATOM   770  O O     . GLY A 1 132 ? 117.851 147.579 120.217 1.00 87.92  ? 132 GLY C O     1 
ATOM   771  N N     . SER A 1 133 ? 115.705 147.158 120.736 1.00 78.63  ? 133 SER C N     1 
ATOM   772  C CA    . SER A 1 133 ? 115.311 148.544 120.527 1.00 82.79  ? 133 SER C CA    1 
ATOM   773  C C     . SER A 1 133 ? 116.021 149.452 121.522 1.00 89.20  ? 133 SER C C     1 
ATOM   774  O O     . SER A 1 133 ? 116.111 149.145 122.713 1.00 92.38  ? 133 SER C O     1 
ATOM   775  C CB    . SER A 1 133 ? 113.797 148.692 120.669 1.00 83.46  ? 133 SER C CB    1 
ATOM   776  O OG    . SER A 1 133 ? 113.114 147.920 119.697 1.00 84.67  ? 133 SER C OG    1 
ATOM   777  N N     . LYS A 1 134 ? 116.524 150.580 121.026 1.00 93.84  ? 134 LYS C N     1 
ATOM   778  C CA    . LYS A 1 134 ? 117.213 151.569 121.842 1.00 96.73  ? 134 LYS C CA    1 
ATOM   779  C C     . LYS A 1 134 ? 116.421 152.868 121.836 1.00 97.52  ? 134 LYS C C     1 
ATOM   780  O O     . LYS A 1 134 ? 115.833 153.243 120.817 1.00 98.49  ? 134 LYS C O     1 
ATOM   781  C CB    . LYS A 1 134 ? 118.634 151.823 121.328 1.00 95.62  ? 134 LYS C CB    1 
ATOM   782  C CG    . LYS A 1 134 ? 119.709 151.005 122.032 1.00 91.45  ? 134 LYS C CG    1 
ATOM   783  C CD    . LYS A 1 134 ? 119.710 149.559 121.565 1.00 92.60  ? 134 LYS C CD    1 
ATOM   784  C CE    . LYS A 1 134 ? 121.112 148.975 121.561 1.00 93.38  ? 134 LYS C CE    1 
ATOM   785  N NZ    . LYS A 1 134 ? 121.124 147.561 121.098 1.00 89.81  ? 134 LYS C NZ    1 
ATOM   786  N N     . MET A 1 135 ? 116.407 153.554 122.981 1.00 93.69  ? 135 MET C N     1 
ATOM   787  C CA    . MET A 1 135 ? 115.647 154.795 123.085 1.00 92.76  ? 135 MET C CA    1 
ATOM   788  C C     . MET A 1 135 ? 116.188 155.854 122.133 1.00 100.43 ? 135 MET C C     1 
ATOM   789  O O     . MET A 1 135 ? 115.419 156.644 121.572 1.00 99.31  ? 135 MET C O     1 
ATOM   790  C CB    . MET A 1 135 ? 115.675 155.304 124.525 1.00 92.26  ? 135 MET C CB    1 
ATOM   791  C CG    . MET A 1 135 ? 114.837 156.552 124.761 1.00 95.45  ? 135 MET C CG    1 
ATOM   792  S SD    . MET A 1 135 ? 113.097 156.184 125.038 1.00 99.93  ? 135 MET C SD    1 
ATOM   793  C CE    . MET A 1 135 ? 112.909 156.703 126.742 1.00 87.63  ? 135 MET C CE    1 
ATOM   794  N N     . LYS A 1 136 ? 117.508 155.891 121.943 1.00 104.33 ? 136 LYS C N     1 
ATOM   795  C CA    . LYS A 1 136 ? 118.105 156.903 121.076 1.00 105.60 ? 136 LYS C CA    1 
ATOM   796  C C     . LYS A 1 136 ? 117.580 156.787 119.650 1.00 103.22 ? 136 LYS C C     1 
ATOM   797  O O     . LYS A 1 136 ? 117.245 157.793 119.016 1.00 101.34 ? 136 LYS C O     1 
ATOM   798  C CB    . LYS A 1 136 ? 119.628 156.774 121.089 1.00 106.21 ? 136 LYS C CB    1 
ATOM   799  C CG    . LYS A 1 136 ? 120.335 157.657 122.104 1.00 110.74 ? 136 LYS C CG    1 
ATOM   800  C CD    . LYS A 1 136 ? 121.737 158.016 121.633 1.00 111.67 ? 136 LYS C CD    1 
ATOM   801  C CE    . LYS A 1 136 ? 122.771 157.747 122.710 1.00 122.99 ? 136 LYS C CE    1 
ATOM   802  N NZ    . LYS A 1 136 ? 124.157 157.992 122.225 1.00 123.65 ? 136 LYS C NZ    1 
ATOM   803  N N     . VAL A 1 137 ? 117.513 155.562 119.123 1.00 99.10  ? 137 VAL C N     1 
ATOM   804  C CA    . VAL A 1 137 ? 117.081 155.376 117.740 1.00 97.14  ? 137 VAL C CA    1 
ATOM   805  C C     . VAL A 1 137 ? 115.632 155.812 117.572 1.00 97.47  ? 137 VAL C C     1 
ATOM   806  O O     . VAL A 1 137 ? 115.283 156.509 116.611 1.00 96.80  ? 137 VAL C O     1 
ATOM   807  C CB    . VAL A 1 137 ? 117.284 153.912 117.309 1.00 97.99  ? 137 VAL C CB    1 
ATOM   808  C CG1   . VAL A 1 137 ? 117.018 153.754 115.818 1.00 96.65  ? 137 VAL C CG1   1 
ATOM   809  C CG2   . VAL A 1 137 ? 118.689 153.446 117.651 1.00 96.69  ? 137 VAL C CG2   1 
ATOM   810  N N     . ILE A 1 138 ? 114.765 155.410 118.503 1.00 99.39  ? 138 ILE C N     1 
ATOM   811  C CA    . ILE A 1 138 ? 113.358 155.790 118.413 1.00 98.28  ? 138 ILE C CA    1 
ATOM   812  C C     . ILE A 1 138 ? 113.215 157.302 118.504 1.00 95.84  ? 138 ILE C C     1 
ATOM   813  O O     . ILE A 1 138 ? 112.444 157.915 117.756 1.00 92.90  ? 138 ILE C O     1 
ATOM   814  C CB    . ILE A 1 138 ? 112.537 155.079 119.506 1.00 97.38  ? 138 ILE C CB    1 
ATOM   815  C CG1   . ILE A 1 138 ? 112.776 153.566 119.476 1.00 92.96  ? 138 ILE C CG1   1 
ATOM   816  C CG2   . ILE A 1 138 ? 111.059 155.380 119.335 1.00 94.83  ? 138 ILE C CG2   1 
ATOM   817  C CD1   . ILE A 1 138 ? 112.528 152.924 118.129 1.00 96.03  ? 138 ILE C CD1   1 
ATOM   818  N N     . LYS A 1 139 ? 113.955 157.929 119.422 1.00 95.00  ? 139 LYS C N     1 
ATOM   819  C CA    . LYS A 1 139 ? 113.894 159.381 119.548 1.00 95.41  ? 139 LYS C CA    1 
ATOM   820  C C     . LYS A 1 139 ? 114.346 160.064 118.264 1.00 95.97  ? 139 LYS C C     1 
ATOM   821  O O     . LYS A 1 139 ? 113.722 161.033 117.814 1.00 94.82  ? 139 LYS C O     1 
ATOM   822  C CB    . LYS A 1 139 ? 114.752 159.838 120.726 1.00 97.85  ? 139 LYS C CB    1 
ATOM   823  C CG    . LYS A 1 139 ? 114.145 159.557 122.090 1.00 98.89  ? 139 LYS C CG    1 
ATOM   824  C CD    . LYS A 1 139 ? 115.021 160.113 123.198 1.00 105.47 ? 139 LYS C CD    1 
ATOM   825  C CE    . LYS A 1 139 ? 114.804 161.604 123.382 1.00 111.80 ? 139 LYS C CE    1 
ATOM   826  N NZ    . LYS A 1 139 ? 116.047 162.301 123.810 1.00 115.39 ? 139 LYS C NZ    1 
ATOM   827  N N     . ALA A 1 140 ? 115.430 159.575 117.659 1.00 97.45  ? 140 ALA C N     1 
ATOM   828  C CA    . ALA A 1 140 ? 115.907 160.166 116.414 1.00 97.22  ? 140 ALA C CA    1 
ATOM   829  C C     . ALA A 1 140 ? 114.875 160.013 115.306 1.00 96.54  ? 140 ALA C C     1 
ATOM   830  O O     . ALA A 1 140 ? 114.653 160.942 114.521 1.00 94.25  ? 140 ALA C O     1 
ATOM   831  C CB    . ALA A 1 140 ? 117.231 159.526 116.000 1.00 97.21  ? 140 ALA C CB    1 
ATOM   832  N N     . SER A 1 141 ? 114.234 158.845 115.226 1.00 99.00  ? 141 SER C N     1 
ATOM   833  C CA    . SER A 1 141 ? 113.234 158.625 114.187 1.00 96.18  ? 141 SER C CA    1 
ATOM   834  C C     . SER A 1 141 ? 112.104 159.641 114.275 1.00 92.75  ? 141 SER C C     1 
ATOM   835  O O     . SER A 1 141 ? 111.475 159.959 113.259 1.00 90.83  ? 141 SER C O     1 
ATOM   836  C CB    . SER A 1 141 ? 112.679 157.205 114.288 1.00 98.12  ? 141 SER C CB    1 
ATOM   837  O OG    . SER A 1 141 ? 113.683 156.294 114.700 1.00 96.44  ? 141 SER C OG    1 
ATOM   838  N N     . GLY A 1 142 ? 111.827 160.156 115.471 1.00 92.08  ? 142 GLY C N     1 
ATOM   839  C CA    . GLY A 1 142 ? 110.795 161.153 115.650 1.00 90.80  ? 142 GLY C CA    1 
ATOM   840  C C     . GLY A 1 142 ? 109.385 160.612 115.723 1.00 89.17  ? 142 GLY C C     1 
ATOM   841  O O     . GLY A 1 142 ? 108.441 161.407 115.804 1.00 90.80  ? 142 GLY C O     1 
ATOM   842  N N     . ASP A 1 143 ? 109.207 159.294 115.695 1.00 88.48  ? 143 ASP C N     1 
ATOM   843  C CA    . ASP A 1 143 ? 107.877 158.702 115.792 1.00 85.48  ? 143 ASP C CA    1 
ATOM   844  C C     . ASP A 1 143 ? 107.342 158.905 117.203 1.00 84.16  ? 143 ASP C C     1 
ATOM   845  O O     . ASP A 1 143 ? 107.881 158.350 118.166 1.00 83.93  ? 143 ASP C O     1 
ATOM   846  C CB    . ASP A 1 143 ? 107.935 157.220 115.435 1.00 80.78  ? 143 ASP C CB    1 
ATOM   847  C CG    . ASP A 1 143 ? 106.567 156.634 115.149 1.00 74.44  ? 143 ASP C CG    1 
ATOM   848  O OD1   . ASP A 1 143 ? 105.568 157.379 115.223 1.00 71.45  ? 143 ASP C OD1   1 
ATOM   849  O OD2   . ASP A 1 143 ? 106.491 155.425 114.850 1.00 73.48  ? 143 ASP C OD2   1 
ATOM   850  N N     . ALA A 1 144 ? 106.282 159.704 117.333 1.00 81.15  ? 144 ALA C N     1 
ATOM   851  C CA    . ALA A 1 144 ? 105.706 159.947 118.651 1.00 79.70  ? 144 ALA C CA    1 
ATOM   852  C C     . ALA A 1 144 ? 105.160 158.661 119.260 1.00 78.85  ? 144 ALA C C     1 
ATOM   853  O O     . ALA A 1 144 ? 105.335 158.409 120.458 1.00 73.00  ? 144 ALA C O     1 
ATOM   854  C CB    . ALA A 1 144 ? 104.606 161.003 118.555 1.00 78.16  ? 144 ALA C CB    1 
ATOM   855  N N     . ALA A 1 145 ? 104.496 157.835 118.450 1.00 77.42  ? 145 ALA C N     1 
ATOM   856  C CA    . ALA A 1 145 ? 103.902 156.608 118.971 1.00 74.14  ? 145 ALA C CA    1 
ATOM   857  C C     . ALA A 1 145 ? 104.967 155.687 119.554 1.00 74.51  ? 145 ALA C C     1 
ATOM   858  O O     . ALA A 1 145 ? 104.815 155.170 120.666 1.00 79.23  ? 145 ALA C O     1 
ATOM   859  C CB    . ALA A 1 145 ? 103.122 155.897 117.865 1.00 74.35  ? 145 ALA C CB    1 
ATOM   860  N N     . MET A 1 146 ? 106.060 155.477 118.820 1.00 72.92  ? 146 MET C N     1 
ATOM   861  C CA    . MET A 1 146 ? 107.110 154.597 119.318 1.00 71.40  ? 146 MET C CA    1 
ATOM   862  C C     . MET A 1 146 ? 107.820 155.202 120.522 1.00 74.86  ? 146 MET C C     1 
ATOM   863  O O     . MET A 1 146 ? 108.222 154.468 121.431 1.00 78.20  ? 146 MET C O     1 
ATOM   864  C CB    . MET A 1 146 ? 108.111 154.290 118.207 1.00 76.99  ? 146 MET C CB    1 
ATOM   865  C CG    . MET A 1 146 ? 107.559 153.383 117.122 1.00 80.36  ? 146 MET C CG    1 
ATOM   866  S SD    . MET A 1 146 ? 107.684 151.636 117.546 1.00 83.85  ? 146 MET C SD    1 
ATOM   867  C CE    . MET A 1 146 ? 107.674 150.889 115.918 1.00 67.70  ? 146 MET C CE    1 
ATOM   868  N N     . ILE A 1 147 ? 107.983 156.526 120.554 1.00 73.64  ? 147 ILE C N     1 
ATOM   869  C CA    . ILE A 1 147 ? 108.599 157.163 121.715 1.00 74.09  ? 147 ILE C CA    1 
ATOM   870  C C     . ILE A 1 147 ? 107.744 156.928 122.954 1.00 74.96  ? 147 ILE C C     1 
ATOM   871  O O     . ILE A 1 147 ? 108.249 156.568 124.026 1.00 75.13  ? 147 ILE C O     1 
ATOM   872  C CB    . ILE A 1 147 ? 108.811 158.665 121.456 1.00 73.37  ? 147 ILE C CB    1 
ATOM   873  C CG1   . ILE A 1 147 ? 109.912 158.877 120.417 1.00 80.93  ? 147 ILE C CG1   1 
ATOM   874  C CG2   . ILE A 1 147 ? 109.170 159.380 122.748 1.00 73.22  ? 147 ILE C CG2   1 
ATOM   875  C CD1   . ILE A 1 147 ? 109.926 160.266 119.818 1.00 82.96  ? 147 ILE C CD1   1 
ATOM   876  N N     . GLN A 1 148 ? 106.432 157.128 122.824 1.00 71.02  ? 148 GLN C N     1 
ATOM   877  C CA    . GLN A 1 148 ? 105.537 156.895 123.951 1.00 67.82  ? 148 GLN C CA    1 
ATOM   878  C C     . GLN A 1 148 ? 105.559 155.432 124.370 1.00 66.57  ? 148 GLN C C     1 
ATOM   879  O O     . GLN A 1 148 ? 105.546 155.121 125.567 1.00 68.21  ? 148 GLN C O     1 
ATOM   880  C CB    . GLN A 1 148 ? 104.118 157.330 123.589 1.00 65.83  ? 148 GLN C CB    1 
ATOM   881  C CG    . GLN A 1 148 ? 103.140 157.293 124.749 1.00 71.37  ? 148 GLN C CG    1 
ATOM   882  C CD    . GLN A 1 148 ? 103.341 158.440 125.718 1.00 76.59  ? 148 GLN C CD    1 
ATOM   883  O OE1   . GLN A 1 148 ? 104.465 158.742 126.116 1.00 75.28  ? 148 GLN C OE1   1 
ATOM   884  N NE2   . GLN A 1 148 ? 102.248 159.087 126.104 1.00 80.80  ? 148 GLN C NE2   1 
ATOM   885  N N     . MET A 1 149 ? 105.588 154.519 123.399 1.00 66.76  ? 149 MET C N     1 
ATOM   886  C CA    . MET A 1 149 ? 105.639 153.099 123.729 1.00 63.12  ? 149 MET C CA    1 
ATOM   887  C C     . MET A 1 149 ? 106.912 152.760 124.495 1.00 60.71  ? 149 MET C C     1 
ATOM   888  O O     . MET A 1 149 ? 106.874 151.999 125.467 1.00 62.10  ? 149 MET C O     1 
ATOM   889  C CB    . MET A 1 149 ? 105.538 152.266 122.453 1.00 65.41  ? 149 MET C CB    1 
ATOM   890  C CG    . MET A 1 149 ? 105.661 150.775 122.677 1.00 64.86  ? 149 MET C CG    1 
ATOM   891  S SD    . MET A 1 149 ? 107.339 150.181 122.428 1.00 65.37  ? 149 MET C SD    1 
ATOM   892  C CE    . MET A 1 149 ? 107.207 149.506 120.778 1.00 66.61  ? 149 MET C CE    1 
ATOM   893  N N     . MET A 1 150 ? 108.049 153.319 124.077 1.00 59.64  ? 150 MET C N     1 
ATOM   894  C CA    . MET A 1 150 ? 109.300 153.051 124.779 1.00 60.20  ? 150 MET C CA    1 
ATOM   895  C C     . MET A 1 150 ? 109.282 153.640 126.184 1.00 63.22  ? 150 MET C C     1 
ATOM   896  O O     . MET A 1 150 ? 109.791 153.024 127.129 1.00 63.97  ? 150 MET C O     1 
ATOM   897  C CB    . MET A 1 150 ? 110.479 153.603 123.983 1.00 62.67  ? 150 MET C CB    1 
ATOM   898  C CG    . MET A 1 150 ? 111.766 152.822 124.177 1.00 72.39  ? 150 MET C CG    1 
ATOM   899  S SD    . MET A 1 150 ? 111.744 151.233 123.328 1.00 92.11  ? 150 MET C SD    1 
ATOM   900  C CE    . MET A 1 150 ? 113.187 150.440 124.030 1.00 75.85  ? 150 MET C CE    1 
ATOM   901  N N     . LYS A 1 151 ? 108.710 154.834 126.344 1.00 63.03  ? 151 LYS C N     1 
ATOM   902  C CA    . LYS A 1 151 ? 108.606 155.419 127.678 1.00 60.34  ? 151 LYS C CA    1 
ATOM   903  C C     . LYS A 1 151 ? 107.739 154.555 128.586 1.00 58.44  ? 151 LYS C C     1 
ATOM   904  O O     . LYS A 1 151 ? 108.080 154.325 129.755 1.00 57.25  ? 151 LYS C O     1 
ATOM   905  C CB    . LYS A 1 151 ? 108.039 156.834 127.583 1.00 62.96  ? 151 LYS C CB    1 
ATOM   906  C CG    . LYS A 1 151 ? 108.990 157.834 126.955 1.00 72.05  ? 151 LYS C CG    1 
ATOM   907  C CD    . LYS A 1 151 ? 108.373 159.220 126.883 1.00 76.59  ? 151 LYS C CD    1 
ATOM   908  C CE    . LYS A 1 151 ? 109.356 160.237 126.325 1.00 80.90  ? 151 LYS C CE    1 
ATOM   909  N NZ    . LYS A 1 151 ? 108.775 161.607 126.270 1.00 84.00  ? 151 LYS C NZ    1 
ATOM   910  N N     . ASP A 1 152 ? 106.612 154.068 128.065 1.00 56.96  ? 152 ASP C N     1 
ATOM   911  C CA    . ASP A 1 152 ? 105.758 153.183 128.847 1.00 52.15  ? 152 ASP C CA    1 
ATOM   912  C C     . ASP A 1 152 ? 106.485 151.893 129.199 1.00 49.38  ? 152 ASP C C     1 
ATOM   913  O O     . ASP A 1 152 ? 106.353 151.382 130.316 1.00 54.15  ? 152 ASP C O     1 
ATOM   914  C CB    . ASP A 1 152 ? 104.476 152.886 128.075 1.00 54.73  ? 152 ASP C CB    1 
ATOM   915  C CG    . ASP A 1 152 ? 103.528 154.066 128.046 1.00 58.79  ? 152 ASP C CG    1 
ATOM   916  O OD1   . ASP A 1 152 ? 103.961 155.181 128.399 1.00 60.56  ? 152 ASP C OD1   1 
ATOM   917  O OD2   . ASP A 1 152 ? 102.354 153.882 127.662 1.00 58.33  ? 152 ASP C OD2   1 
ATOM   918  N N     . HIS A 1 153 ? 107.257 151.350 128.258 1.00 46.74  ? 153 HIS C N     1 
ATOM   919  C CA    . HIS A 1 153 ? 108.028 150.145 128.539 1.00 47.58  ? 153 HIS C CA    1 
ATOM   920  C C     . HIS A 1 153 ? 109.029 150.384 129.661 1.00 49.89  ? 153 HIS C C     1 
ATOM   921  O O     . HIS A 1 153 ? 109.180 149.547 130.559 1.00 52.76  ? 153 HIS C O     1 
ATOM   922  C CB    . HIS A 1 153 ? 108.740 149.684 127.267 1.00 49.34  ? 153 HIS C CB    1 
ATOM   923  C CG    . HIS A 1 153 ? 109.888 148.755 127.510 1.00 40.81  ? 153 HIS C CG    1 
ATOM   924  N ND1   . HIS A 1 153 ? 109.781 147.390 127.370 1.00 37.41  ? 153 HIS C ND1   1 
ATOM   925  C CD2   . HIS A 1 153 ? 111.171 148.996 127.865 1.00 46.89  ? 153 HIS C CD2   1 
ATOM   926  C CE1   . HIS A 1 153 ? 110.945 146.828 127.637 1.00 41.03  ? 153 HIS C CE1   1 
ATOM   927  N NE2   . HIS A 1 153 ? 111.806 147.781 127.942 1.00 46.97  ? 153 HIS C NE2   1 
ATOM   928  N N     . ASN A 1 154 ? 109.726 151.521 129.628 1.00 50.56  ? 154 ASN C N     1 
ATOM   929  C CA    . ASN A 1 154 ? 110.691 151.823 130.683 1.00 49.93  ? 154 ASN C CA    1 
ATOM   930  C C     . ASN A 1 154 ? 110.003 151.965 132.036 1.00 48.28  ? 154 ASN C C     1 
ATOM   931  O O     . ASN A 1 154 ? 110.484 151.437 133.049 1.00 47.47  ? 154 ASN C O     1 
ATOM   932  C CB    . ASN A 1 154 ? 111.459 153.095 130.336 1.00 54.43  ? 154 ASN C CB    1 
ATOM   933  C CG    . ASN A 1 154 ? 112.422 152.895 129.187 1.00 59.97  ? 154 ASN C CG    1 
ATOM   934  O OD1   . ASN A 1 154 ? 112.343 153.579 128.169 1.00 61.75  ? 154 ASN C OD1   1 
ATOM   935  N ND2   . ASN A 1 154 ? 113.342 151.956 129.346 1.00 66.61  ? 154 ASN C ND2   1 
ATOM   936  N N     . SER A 1 155 ? 108.875 152.678 132.075 1.00 49.71  ? 155 SER C N     1 
ATOM   937  C CA    . SER A 1 155 ? 108.154 152.832 133.335 1.00 51.86  ? 155 SER C CA    1 
ATOM   938  C C     . SER A 1 155 ? 107.693 151.483 133.869 1.00 44.07  ? 155 SER C C     1 
ATOM   939  O O     . SER A 1 155 ? 107.783 151.215 135.076 1.00 42.21  ? 155 SER C O     1 
ATOM   940  C CB    . SER A 1 155 ? 106.962 153.767 133.145 1.00 58.10  ? 155 SER C CB    1 
ATOM   941  O OG    . SER A 1 155 ? 107.309 154.879 132.340 1.00 59.32  ? 155 SER C OG    1 
ATOM   942  N N     . LEU A 1 156 ? 107.192 150.620 132.985 1.00 41.54  ? 156 LEU C N     1 
ATOM   943  C CA    . LEU A 1 156 ? 106.758 149.298 133.411 1.00 39.89  ? 156 LEU C CA    1 
ATOM   944  C C     . LEU A 1 156 ? 107.927 148.491 133.952 1.00 39.07  ? 156 LEU C C     1 
ATOM   945  O O     . LEU A 1 156 ? 107.787 147.778 134.951 1.00 45.99  ? 156 LEU C O     1 
ATOM   946  C CB    . LEU A 1 156 ? 106.094 148.566 132.249 1.00 40.51  ? 156 LEU C CB    1 
ATOM   947  C CG    . LEU A 1 156 ? 105.362 147.279 132.621 1.00 40.30  ? 156 LEU C CG    1 
ATOM   948  C CD1   . LEU A 1 156 ? 104.077 147.593 133.353 1.00 42.15  ? 156 LEU C CD1   1 
ATOM   949  C CD2   . LEU A 1 156 ? 105.084 146.458 131.384 1.00 49.54  ? 156 LEU C CD2   1 
ATOM   950  N N     . LEU A 1 157 ? 109.089 148.583 133.305 1.00 34.14  ? 157 LEU C N     1 
ATOM   951  C CA    . LEU A 1 157 ? 110.259 147.876 133.814 1.00 32.69  ? 157 LEU C CA    1 
ATOM   952  C C     . LEU A 1 157 ? 110.615 148.352 135.214 1.00 36.32  ? 157 LEU C C     1 
ATOM   953  O O     . LEU A 1 157 ? 110.899 147.540 136.102 1.00 35.03  ? 157 LEU C O     1 
ATOM   954  C CB    . LEU A 1 157 ? 111.447 148.071 132.873 1.00 35.47  ? 157 LEU C CB    1 
ATOM   955  C CG    . LEU A 1 157 ? 111.497 147.258 131.579 1.00 38.45  ? 157 LEU C CG    1 
ATOM   956  C CD1   . LEU A 1 157 ? 112.881 147.355 130.967 1.00 40.01  ? 157 LEU C CD1   1 
ATOM   957  C CD2   . LEU A 1 157 ? 111.126 145.810 131.814 1.00 39.79  ? 157 LEU C CD2   1 
ATOM   958  N N     . ARG A 1 158 ? 110.600 149.667 135.434 1.00 39.36  ? 158 ARG C N     1 
ATOM   959  C CA    . ARG A 1 158 ? 110.957 150.189 136.751 1.00 35.66  ? 158 ARG C CA    1 
ATOM   960  C C     . ARG A 1 158 ? 109.974 149.715 137.817 1.00 37.50  ? 158 ARG C C     1 
ATOM   961  O O     . ARG A 1 158 ? 110.378 149.271 138.900 1.00 40.20  ? 158 ARG C O     1 
ATOM   962  C CB    . ARG A 1 158 ? 111.015 151.715 136.710 1.00 39.88  ? 158 ARG C CB    1 
ATOM   963  C CG    . ARG A 1 158 ? 112.390 152.267 136.378 1.00 44.32  ? 158 ARG C CG    1 
ATOM   964  C CD    . ARG A 1 158 ? 112.514 153.725 136.776 1.00 52.72  ? 158 ARG C CD    1 
ATOM   965  N NE    . ARG A 1 158 ? 111.662 154.588 135.966 1.00 63.17  ? 158 ARG C NE    1 
ATOM   966  C CZ    . ARG A 1 158 ? 111.922 154.942 134.714 1.00 58.89  ? 158 ARG C CZ    1 
ATOM   967  N NH1   . ARG A 1 158 ? 113.013 154.525 134.090 1.00 58.05  ? 158 ARG C NH1   1 
ATOM   968  N NH2   . ARG A 1 158 ? 111.068 155.733 134.073 1.00 59.08  ? 158 ARG C NH2   1 
ATOM   969  N N     . VAL A 1 159 ? 108.673 149.793 137.525 1.00 37.79  ? 159 VAL C N     1 
ATOM   970  C CA    . VAL A 1 159 ? 107.677 149.381 138.514 1.00 31.19  ? 159 VAL C CA    1 
ATOM   971  C C     . VAL A 1 159 ? 107.792 147.890 138.802 1.00 29.29  ? 159 VAL C C     1 
ATOM   972  O O     . VAL A 1 159 ? 107.721 147.458 139.961 1.00 32.29  ? 159 VAL C O     1 
ATOM   973  C CB    . VAL A 1 159 ? 106.262 149.756 138.040 1.00 32.82  ? 159 VAL C CB    1 
ATOM   974  C CG1   . VAL A 1 159 ? 105.225 149.188 138.981 1.00 33.63  ? 159 VAL C CG1   1 
ATOM   975  C CG2   . VAL A 1 159 ? 106.122 151.259 137.952 1.00 45.51  ? 159 VAL C CG2   1 
ATOM   976  N N     . CYS A 1 160 ? 107.963 147.078 137.756 1.00 30.08  ? 160 CYS C N     1 
ATOM   977  C CA    . CYS A 1 160 ? 108.083 145.639 137.955 1.00 25.74  ? 160 CYS C CA    1 
ATOM   978  C C     . CYS A 1 160 ? 109.324 145.299 138.765 1.00 27.15  ? 160 CYS C C     1 
ATOM   979  O O     . CYS A 1 160 ? 109.299 144.382 139.589 1.00 27.41  ? 160 CYS C O     1 
ATOM   980  C CB    . CYS A 1 160 ? 108.109 144.927 136.606 1.00 27.24  ? 160 CYS C CB    1 
ATOM   981  S SG    . CYS A 1 160 ? 106.535 144.960 135.730 1.00 45.21  ? 160 CYS C SG    1 
ATOM   982  N N     . VAL A 1 161 ? 110.419 146.029 138.556 1.00 31.98  ? 161 VAL C N     1 
ATOM   983  C CA    . VAL A 1 161 ? 111.627 145.761 139.327 1.00 31.35  ? 161 VAL C CA    1 
ATOM   984  C C     . VAL A 1 161 ? 111.429 146.144 140.788 1.00 33.58  ? 161 VAL C C     1 
ATOM   985  O O     . VAL A 1 161 ? 111.910 145.452 141.692 1.00 36.48  ? 161 VAL C O     1 
ATOM   986  C CB    . VAL A 1 161 ? 112.828 146.493 138.710 1.00 32.41  ? 161 VAL C CB    1 
ATOM   987  C CG1   . VAL A 1 161 ? 113.960 146.583 139.714 1.00 34.24  ? 161 VAL C CG1   1 
ATOM   988  C CG2   . VAL A 1 161 ? 113.279 145.778 137.453 1.00 37.41  ? 161 VAL C CG2   1 
ATOM   989  N N     . ARG A 1 162 ? 110.740 147.256 141.048 1.00 33.80  ? 162 ARG C N     1 
ATOM   990  C CA    . ARG A 1 162 ? 110.462 147.622 142.435 1.00 30.16  ? 162 ARG C CA    1 
ATOM   991  C C     . ARG A 1 162 ? 109.622 146.552 143.121 1.00 28.13  ? 162 ARG C C     1 
ATOM   992  O O     . ARG A 1 162 ? 109.909 146.154 144.259 1.00 28.22  ? 162 ARG C O     1 
ATOM   993  C CB    . ARG A 1 162 ? 109.758 148.974 142.488 1.00 30.81  ? 162 ARG C CB    1 
ATOM   994  C CG    . ARG A 1 162 ? 110.706 150.154 142.588 1.00 33.37  ? 162 ARG C CG    1 
ATOM   995  C CD    . ARG A 1 162 ? 110.073 151.428 142.063 1.00 36.45  ? 162 ARG C CD    1 
ATOM   996  N NE    . ARG A 1 162 ? 109.090 151.977 142.988 1.00 40.76  ? 162 ARG C NE    1 
ATOM   997  C CZ    . ARG A 1 162 ? 109.392 152.657 144.086 1.00 49.00  ? 162 ARG C CZ    1 
ATOM   998  N NH1   . ARG A 1 162 ? 110.648 152.884 144.436 1.00 47.96  ? 162 ARG C NH1   1 
ATOM   999  N NH2   . ARG A 1 162 ? 108.410 153.120 144.853 1.00 49.40  ? 162 ARG C NH2   1 
ATOM   1000 N N     . ILE A 1 163 ? 108.587 146.061 142.438 1.00 29.17  ? 163 ILE C N     1 
ATOM   1001 C CA    . ILE A 1 163 ? 107.760 145.003 143.011 1.00 24.51  ? 163 ILE C CA    1 
ATOM   1002 C C     . ILE A 1 163 ? 108.586 143.741 143.232 1.00 27.45  ? 163 ILE C C     1 
ATOM   1003 O O     . ILE A 1 163 ? 108.418 143.040 144.235 1.00 32.08  ? 163 ILE C O     1 
ATOM   1004 C CB    . ILE A 1 163 ? 106.542 144.731 142.111 1.00 25.67  ? 163 ILE C CB    1 
ATOM   1005 C CG1   . ILE A 1 163 ? 105.528 145.865 142.251 1.00 26.25  ? 163 ILE C CG1   1 
ATOM   1006 C CG2   . ILE A 1 163 ? 105.917 143.396 142.466 1.00 30.11  ? 163 ILE C CG2   1 
ATOM   1007 C CD1   . ILE A 1 163 ? 104.352 145.763 141.315 1.00 27.99  ? 163 ILE C CD1   1 
ATOM   1008 N N     . GLU A 1 164 ? 109.483 143.426 142.296 1.00 29.89  ? 164 GLU C N     1 
ATOM   1009 C CA    . GLU A 1 164 ? 110.327 142.246 142.444 1.00 29.65  ? 164 GLU C CA    1 
ATOM   1010 C C     . GLU A 1 164 ? 111.228 142.364 143.664 1.00 29.99  ? 164 GLU C C     1 
ATOM   1011 O O     . GLU A 1 164 ? 111.403 141.396 144.411 1.00 33.36  ? 164 GLU C O     1 
ATOM   1012 C CB    . GLU A 1 164 ? 111.160 142.048 141.179 1.00 35.84  ? 164 GLU C CB    1 
ATOM   1013 C CG    . GLU A 1 164 ? 112.176 140.925 141.257 1.00 40.67  ? 164 GLU C CG    1 
ATOM   1014 C CD    . GLU A 1 164 ? 112.865 140.679 139.928 1.00 49.77  ? 164 GLU C CD    1 
ATOM   1015 O OE1   . GLU A 1 164 ? 112.925 141.617 139.108 1.00 42.45  ? 164 GLU C OE1   1 
ATOM   1016 O OE2   . GLU A 1 164 ? 113.341 139.548 139.701 1.00 56.77  ? 164 GLU C OE2   1 
ATOM   1017 N N     . VAL A 1 165 ? 111.817 143.542 143.879 1.00 30.27  ? 165 VAL C N     1 
ATOM   1018 C CA    . VAL A 1 165 ? 112.677 143.741 145.043 1.00 26.88  ? 165 VAL C CA    1 
ATOM   1019 C C     . VAL A 1 165 ? 111.873 143.598 146.327 1.00 25.05  ? 165 VAL C C     1 
ATOM   1020 O O     . VAL A 1 165 ? 112.322 142.968 147.295 1.00 25.44  ? 165 VAL C O     1 
ATOM   1021 C CB    . VAL A 1 165 ? 113.372 145.112 144.969 1.00 25.93  ? 165 VAL C CB    1 
ATOM   1022 C CG1   . VAL A 1 165 ? 114.026 145.439 146.292 1.00 23.51  ? 165 VAL C CG1   1 
ATOM   1023 C CG2   . VAL A 1 165 ? 114.392 145.125 143.852 1.00 30.39  ? 165 VAL C CG2   1 
ATOM   1024 N N     . TRP A 1 166 ? 110.676 144.184 146.363 1.00 26.35  ? 166 TRP C N     1 
ATOM   1025 C CA    . TRP A 1 166 ? 109.858 144.062 147.564 1.00 24.63  ? 166 TRP C CA    1 
ATOM   1026 C C     . TRP A 1 166 ? 109.495 142.610 147.832 1.00 28.69  ? 166 TRP C C     1 
ATOM   1027 O O     . TRP A 1 166 ? 109.497 142.168 148.985 1.00 37.31  ? 166 TRP C O     1 
ATOM   1028 C CB    . TRP A 1 166 ? 108.596 144.905 147.445 1.00 27.40  ? 166 TRP C CB    1 
ATOM   1029 C CG    . TRP A 1 166 ? 107.742 144.824 148.662 1.00 26.47  ? 166 TRP C CG    1 
ATOM   1030 C CD1   . TRP A 1 166 ? 107.730 145.691 149.707 1.00 32.41  ? 166 TRP C CD1   1 
ATOM   1031 C CD2   . TRP A 1 166 ? 106.775 143.815 148.966 1.00 29.08  ? 166 TRP C CD2   1 
ATOM   1032 N NE1   . TRP A 1 166 ? 106.814 145.290 150.646 1.00 34.33  ? 166 TRP C NE1   1 
ATOM   1033 C CE2   . TRP A 1 166 ? 106.213 144.139 150.213 1.00 32.33  ? 166 TRP C CE2   1 
ATOM   1034 C CE3   . TRP A 1 166 ? 106.328 142.671 148.303 1.00 31.93  ? 166 TRP C CE3   1 
ATOM   1035 C CZ2   . TRP A 1 166 ? 105.230 143.362 150.811 1.00 34.97  ? 166 TRP C CZ2   1 
ATOM   1036 C CZ3   . TRP A 1 166 ? 105.351 141.901 148.898 1.00 37.02  ? 166 TRP C CZ3   1 
ATOM   1037 C CH2   . TRP A 1 166 ? 104.812 142.249 150.139 1.00 36.59  ? 166 TRP C CH2   1 
ATOM   1038 N N     . LYS A 1 167 ? 109.162 141.853 146.786 1.00 28.80  ? 167 LYS C N     1 
ATOM   1039 C CA    . LYS A 1 167 ? 108.823 140.448 146.988 1.00 29.56  ? 167 LYS C CA    1 
ATOM   1040 C C     . LYS A 1 167 ? 110.035 139.649 147.444 1.00 30.07  ? 167 LYS C C     1 
ATOM   1041 O O     . LYS A 1 167 ? 109.901 138.714 148.238 1.00 32.35  ? 167 LYS C O     1 
ATOM   1042 C CB    . LYS A 1 167 ? 108.244 139.849 145.710 1.00 33.67  ? 167 LYS C CB    1 
ATOM   1043 C CG    . LYS A 1 167 ? 107.742 138.424 145.872 1.00 36.48  ? 167 LYS C CG    1 
ATOM   1044 C CD    . LYS A 1 167 ? 106.677 138.327 146.951 1.00 39.52  ? 167 LYS C CD    1 
ATOM   1045 C CE    . LYS A 1 167 ? 105.832 137.073 146.798 1.00 42.28  ? 167 LYS C CE    1 
ATOM   1046 N NZ    . LYS A 1 167 ? 106.664 135.848 146.653 1.00 46.09  ? 167 LYS C NZ    1 
ATOM   1047 N N     . ALA A 1 168 ? 111.224 139.989 146.946 1.00 28.97  ? 168 ALA C N     1 
ATOM   1048 C CA    . ALA A 1 168 ? 112.431 139.330 147.434 1.00 26.60  ? 168 ALA C CA    1 
ATOM   1049 C C     . ALA A 1 168 ? 112.624 139.584 148.921 1.00 29.95  ? 168 ALA C C     1 
ATOM   1050 O O     . ALA A 1 168 ? 112.924 138.659 149.687 1.00 36.73  ? 168 ALA C O     1 
ATOM   1051 C CB    . ALA A 1 168 ? 113.649 139.810 146.648 1.00 27.65  ? 168 ALA C CB    1 
ATOM   1052 N N     . ARG A 1 169 ? 112.441 140.832 149.353 1.00 30.14  ? 169 ARG C N     1 
ATOM   1053 C CA    . ARG A 1 169 ? 112.562 141.135 150.776 1.00 28.36  ? 169 ARG C CA    1 
ATOM   1054 C C     . ARG A 1 169 ? 111.510 140.390 151.588 1.00 30.50  ? 169 ARG C C     1 
ATOM   1055 O O     . ARG A 1 169 ? 111.801 139.876 152.672 1.00 33.00  ? 169 ARG C O     1 
ATOM   1056 C CB    . ARG A 1 169 ? 112.441 142.638 151.007 1.00 26.40  ? 169 ARG C CB    1 
ATOM   1057 C CG    . ARG A 1 169 ? 113.625 143.433 150.506 1.00 23.68  ? 169 ARG C CG    1 
ATOM   1058 C CD    . ARG A 1 169 ? 113.739 144.742 151.244 1.00 22.95  ? 169 ARG C CD    1 
ATOM   1059 N NE    . ARG A 1 169 ? 114.099 145.839 150.356 1.00 22.18  ? 169 ARG C NE    1 
ATOM   1060 C CZ    . ARG A 1 169 ? 113.469 147.005 150.298 1.00 28.18  ? 169 ARG C CZ    1 
ATOM   1061 N NH1   . ARG A 1 169 ? 112.412 147.264 151.049 1.00 27.67  ? 169 ARG C NH1   1 
ATOM   1062 N NH2   . ARG A 1 169 ? 113.907 147.935 149.456 1.00 31.49  ? 169 ARG C NH2   1 
ATOM   1063 N N     . TYR A 1 170 ? 110.279 140.326 151.079 1.00 29.64  ? 170 TYR C N     1 
ATOM   1064 C CA    . TYR A 1 170 ? 109.213 139.619 151.783 1.00 29.94  ? 170 TYR C CA    1 
ATOM   1065 C C     . TYR A 1 170 ? 109.521 138.133 151.911 1.00 36.37  ? 170 TYR C C     1 
ATOM   1066 O O     . TYR A 1 170 ? 109.260 137.524 152.954 1.00 40.83  ? 170 TYR C O     1 
ATOM   1067 C CB    . TYR A 1 170 ? 107.891 139.834 151.050 1.00 28.96  ? 170 TYR C CB    1 
ATOM   1068 C CG    . TYR A 1 170 ? 106.695 139.163 151.680 1.00 33.27  ? 170 TYR C CG    1 
ATOM   1069 C CD1   . TYR A 1 170 ? 106.393 137.840 151.403 1.00 37.87  ? 170 TYR C CD1   1 
ATOM   1070 C CD2   . TYR A 1 170 ? 105.853 139.860 152.530 1.00 37.21  ? 170 TYR C CD2   1 
ATOM   1071 C CE1   . TYR A 1 170 ? 105.296 137.226 151.967 1.00 40.10  ? 170 TYR C CE1   1 
ATOM   1072 C CE2   . TYR A 1 170 ? 104.752 139.254 153.098 1.00 40.11  ? 170 TYR C CE2   1 
ATOM   1073 C CZ    . TYR A 1 170 ? 104.478 137.937 152.813 1.00 38.43  ? 170 TYR C CZ    1 
ATOM   1074 O OH    . TYR A 1 170 ? 103.382 137.325 153.375 1.00 38.63  ? 170 TYR C OH    1 
ATOM   1075 N N     . VAL A 1 171 ? 110.064 137.527 150.856 1.00 38.50  ? 171 VAL C N     1 
ATOM   1076 C CA    . VAL A 1 171 ? 110.410 136.111 150.909 1.00 37.24  ? 171 VAL C CA    1 
ATOM   1077 C C     . VAL A 1 171 ? 111.554 135.878 151.884 1.00 37.85  ? 171 VAL C C     1 
ATOM   1078 O O     . VAL A 1 171 ? 111.577 134.873 152.603 1.00 43.17  ? 171 VAL C O     1 
ATOM   1079 C CB    . VAL A 1 171 ? 110.756 135.596 149.500 1.00 40.72  ? 171 VAL C CB    1 
ATOM   1080 C CG1   . VAL A 1 171 ? 111.731 134.429 149.572 1.00 40.50  ? 171 VAL C CG1   1 
ATOM   1081 C CG2   . VAL A 1 171 ? 109.495 135.188 148.763 1.00 45.02  ? 171 VAL C CG2   1 
ATOM   1082 N N     . SER A 1 172 ? 112.518 136.798 151.931 1.00 37.91  ? 172 SER C N     1 
ATOM   1083 C CA    . SER A 1 172 ? 113.697 136.590 152.762 1.00 42.28  ? 172 SER C CA    1 
ATOM   1084 C C     . SER A 1 172 ? 113.387 136.601 154.253 1.00 45.61  ? 172 SER C C     1 
ATOM   1085 O O     . SER A 1 172 ? 114.257 136.228 155.047 1.00 52.06  ? 172 SER C O     1 
ATOM   1086 C CB    . SER A 1 172 ? 114.747 137.656 152.457 1.00 40.10  ? 172 SER C CB    1 
ATOM   1087 O OG    . SER A 1 172 ? 114.726 138.679 153.433 1.00 38.55  ? 172 SER C OG    1 
ATOM   1088 N N     . LEU A 1 173 ? 112.186 137.016 154.657 1.00 41.76  ? 173 LEU C N     1 
ATOM   1089 C CA    . LEU A 1 173 ? 111.886 137.106 156.082 1.00 44.54  ? 173 LEU C CA    1 
ATOM   1090 C C     . LEU A 1 173 ? 111.759 135.733 156.728 1.00 49.72  ? 173 LEU C C     1 
ATOM   1091 O O     . LEU A 1 173 ? 112.029 135.592 157.925 1.00 54.64  ? 173 LEU C O     1 
ATOM   1092 C CB    . LEU A 1 173 ? 110.598 137.900 156.303 1.00 40.41  ? 173 LEU C CB    1 
ATOM   1093 C CG    . LEU A 1 173 ? 110.655 139.418 156.131 1.00 34.97  ? 173 LEU C CG    1 
ATOM   1094 C CD1   . LEU A 1 173 ? 109.304 140.016 156.454 1.00 33.90  ? 173 LEU C CD1   1 
ATOM   1095 C CD2   . LEU A 1 173 ? 111.728 140.036 156.997 1.00 36.82  ? 173 LEU C CD2   1 
ATOM   1096 N N     . VAL A 1 174 ? 111.350 134.716 155.970 1.00 51.70  ? 174 VAL C N     1 
ATOM   1097 C CA    . VAL A 1 174 ? 111.043 133.410 156.548 1.00 54.91  ? 174 VAL C CA    1 
ATOM   1098 C C     . VAL A 1 174 ? 111.845 132.304 155.873 1.00 55.67  ? 174 VAL C C     1 
ATOM   1099 O O     . VAL A 1 174 ? 111.829 131.154 156.324 1.00 57.96  ? 174 VAL C O     1 
ATOM   1100 C CB    . VAL A 1 174 ? 109.535 133.115 156.456 1.00 52.65  ? 174 VAL C CB    1 
ATOM   1101 C CG1   . VAL A 1 174 ? 108.738 134.203 157.153 1.00 51.07  ? 174 VAL C CG1   1 
ATOM   1102 C CG2   . VAL A 1 174 ? 109.105 132.976 155.004 1.00 51.31  ? 174 VAL C CG2   1 
ATOM   1103 N N     . ALA A 1 175 ? 112.550 132.633 154.790 1.00 58.81  ? 175 ALA C N     1 
ATOM   1104 C CA    . ALA A 1 175 ? 113.320 131.628 154.056 1.00 61.12  ? 175 ALA C CA    1 
ATOM   1105 C C     . ALA A 1 175 ? 114.552 132.315 153.474 1.00 63.18  ? 175 ALA C C     1 
ATOM   1106 O O     . ALA A 1 175 ? 114.471 132.951 152.420 1.00 63.45  ? 175 ALA C O     1 
ATOM   1107 C CB    . ALA A 1 175 ? 112.476 130.978 152.969 1.00 55.10  ? 175 ALA C CB    1 
ATOM   1108 N N     . LEU A 1 176 ? 115.683 132.171 154.156 1.00 68.87  ? 176 LEU C N     1 
ATOM   1109 C CA    . LEU A 1 176 ? 116.914 132.792 153.698 1.00 71.97  ? 176 LEU C CA    1 
ATOM   1110 C C     . LEU A 1 176 ? 117.489 132.044 152.499 1.00 81.56  ? 176 LEU C C     1 
ATOM   1111 O O     . LEU A 1 176 ? 117.142 130.893 152.218 1.00 85.69  ? 176 LEU C O     1 
ATOM   1112 C CB    . LEU A 1 176 ? 117.950 132.826 154.820 1.00 74.23  ? 176 LEU C CB    1 
ATOM   1113 C CG    . LEU A 1 176 ? 117.548 133.575 156.088 1.00 73.95  ? 176 LEU C CG    1 
ATOM   1114 C CD1   . LEU A 1 176 ? 118.707 133.597 157.073 1.00 76.08  ? 176 LEU C CD1   1 
ATOM   1115 C CD2   . LEU A 1 176 ? 117.088 134.984 155.757 1.00 72.45  ? 176 LEU C CD2   1 
ATOM   1116 N N     . ASP A 1 177 ? 118.385 132.722 151.789 1.00 83.09  ? 177 ASP C N     1 
ATOM   1117 C CA    . ASP A 1 177 ? 119.113 132.126 150.681 1.00 87.16  ? 177 ASP C CA    1 
ATOM   1118 C C     . ASP A 1 177 ? 120.372 131.449 151.206 1.00 87.79  ? 177 ASP C C     1 
ATOM   1119 O O     . ASP A 1 177 ? 121.060 131.985 152.079 1.00 86.58  ? 177 ASP C O     1 
ATOM   1120 C CB    . ASP A 1 177 ? 119.480 133.188 149.644 1.00 88.67  ? 177 ASP C CB    1 
ATOM   1121 C CG    . ASP A 1 177 ? 119.422 132.662 148.223 1.00 84.90  ? 177 ASP C CG    1 
ATOM   1122 O OD1   . ASP A 1 177 ? 118.303 132.431 147.721 1.00 83.95  ? 177 ASP C OD1   1 
ATOM   1123 O OD2   . ASP A 1 177 ? 120.495 132.481 147.609 1.00 78.68  ? 177 ASP C OD2   1 
ATOM   1124 N N     . GLU A 1 178 ? 120.667 130.264 150.670 1.00 90.51  ? 178 GLU C N     1 
ATOM   1125 C CA    . GLU A 1 178 ? 121.844 129.532 151.123 1.00 94.27  ? 178 GLU C CA    1 
ATOM   1126 C C     . GLU A 1 178 ? 123.126 130.301 150.839 1.00 91.31  ? 178 GLU C C     1 
ATOM   1127 O O     . GLU A 1 178 ? 124.129 130.111 151.534 1.00 89.90  ? 178 GLU C O     1 
ATOM   1128 C CB    . GLU A 1 178 ? 121.895 128.156 150.461 1.00 95.99  ? 178 GLU C CB    1 
ATOM   1129 C CG    . GLU A 1 178 ? 121.460 127.018 151.371 1.00 95.32  ? 178 GLU C CG    1 
ATOM   1130 C CD    . GLU A 1 178 ? 120.021 127.152 151.828 1.00 96.20  ? 178 GLU C CD    1 
ATOM   1131 O OE1   . GLU A 1 178 ? 119.310 128.037 151.309 1.00 94.71  ? 178 GLU C OE1   1 
ATOM   1132 O OE2   . GLU A 1 178 ? 119.602 126.372 152.708 1.00 97.87  ? 178 GLU C OE2   1 
ATOM   1133 N N     . ARG A 1 179 ? 123.116 131.171 149.827 1.00 86.29  ? 179 ARG C N     1 
ATOM   1134 C CA    . ARG A 1 179 ? 124.315 131.931 149.495 1.00 83.91  ? 179 ARG C CA    1 
ATOM   1135 C C     . ARG A 1 179 ? 124.738 132.857 150.625 1.00 80.47  ? 179 ARG C C     1 
ATOM   1136 O O     . ARG A 1 179 ? 125.921 133.200 150.719 1.00 79.31  ? 179 ARG C O     1 
ATOM   1137 C CB    . ARG A 1 179 ? 124.086 132.748 148.222 1.00 83.79  ? 179 ARG C CB    1 
ATOM   1138 C CG    . ARG A 1 179 ? 125.296 133.570 147.790 1.00 79.08  ? 179 ARG C CG    1 
ATOM   1139 C CD    . ARG A 1 179 ? 125.025 134.406 146.545 1.00 75.37  ? 179 ARG C CD    1 
ATOM   1140 N NE    . ARG A 1 179 ? 124.225 133.707 145.546 1.00 75.41  ? 179 ARG C NE    1 
ATOM   1141 C CZ    . ARG A 1 179 ? 122.901 133.751 145.470 1.00 71.95  ? 179 ARG C CZ    1 
ATOM   1142 N NH1   . ARG A 1 179 ? 122.179 134.438 146.340 1.00 71.33  ? 179 ARG C NH1   1 
ATOM   1143 N NH2   . ARG A 1 179 ? 122.286 133.090 144.494 1.00 75.01  ? 179 ARG C NH2   1 
ATOM   1144 N N     . ILE A 1 180 ? 123.806 133.269 151.481 1.00 81.43  ? 180 ILE C N     1 
ATOM   1145 C CA    . ILE A 1 180 ? 124.095 134.231 152.545 1.00 85.46  ? 180 ILE C CA    1 
ATOM   1146 C C     . ILE A 1 180 ? 124.626 133.428 153.729 1.00 89.13  ? 180 ILE C C     1 
ATOM   1147 O O     . ILE A 1 180 ? 123.870 132.917 154.557 1.00 84.36  ? 180 ILE C O     1 
ATOM   1148 C CB    . ILE A 1 180 ? 122.870 135.063 152.908 1.00 80.81  ? 180 ILE C CB    1 
ATOM   1149 C CG1   . ILE A 1 180 ? 122.511 136.002 151.757 1.00 73.41  ? 180 ILE C CG1   1 
ATOM   1150 C CG2   . ILE A 1 180 ? 123.132 135.860 154.172 1.00 79.53  ? 180 ILE C CG2   1 
ATOM   1151 C CD1   . ILE A 1 180 ? 121.050 136.374 151.713 1.00 74.12  ? 180 ILE C CD1   1 
ATOM   1152 N N     . GLN A 1 181 ? 125.954 133.317 153.807 1.00 89.84  ? 181 GLN C N     1 
ATOM   1153 C CA    . GLN A 1 181 ? 126.612 132.645 154.916 1.00 86.40  ? 181 GLN C CA    1 
ATOM   1154 C C     . GLN A 1 181 ? 127.638 133.524 155.616 1.00 85.18  ? 181 GLN C C     1 
ATOM   1155 O O     . GLN A 1 181 ? 128.161 133.121 156.660 1.00 89.37  ? 181 GLN C O     1 
ATOM   1156 C CB    . GLN A 1 181 ? 127.298 131.358 154.435 1.00 89.34  ? 181 GLN C CB    1 
ATOM   1157 C CG    . GLN A 1 181 ? 126.374 130.411 153.691 1.00 92.49  ? 181 GLN C CG    1 
ATOM   1158 C CD    . GLN A 1 181 ? 125.248 129.895 154.564 1.00 93.51  ? 181 GLN C CD    1 
ATOM   1159 O OE1   . GLN A 1 181 ? 125.304 129.991 155.790 1.00 98.40  ? 181 GLN C OE1   1 
ATOM   1160 N NE2   . GLN A 1 181 ? 124.221 129.337 153.937 1.00 88.37  ? 181 GLN C NE2   1 
ATOM   1161 N N     . THR A 1 182 ? 127.941 134.702 155.078 1.00 79.44  ? 182 THR C N     1 
ATOM   1162 C CA    . THR A 1 182 ? 128.864 135.629 155.713 1.00 78.97  ? 182 THR C CA    1 
ATOM   1163 C C     . THR A 1 182 ? 128.378 137.044 155.442 1.00 77.08  ? 182 THR C C     1 
ATOM   1164 O O     . THR A 1 182 ? 127.556 137.279 154.554 1.00 79.38  ? 182 THR C O     1 
ATOM   1165 C CB    . THR A 1 182 ? 130.297 135.435 155.206 1.00 80.74  ? 182 THR C CB    1 
ATOM   1166 O OG1   . THR A 1 182 ? 130.282 135.190 153.795 1.00 80.34  ? 182 THR C OG1   1 
ATOM   1167 C CG2   . THR A 1 182 ? 130.960 134.264 155.915 1.00 81.08  ? 182 THR C CG2   1 
ATOM   1168 N N     . LEU A 1 183 ? 128.896 137.993 156.224 1.00 72.40  ? 183 LEU C N     1 
ATOM   1169 C CA    . LEU A 1 183 ? 128.433 139.371 156.102 1.00 71.87  ? 183 LEU C CA    1 
ATOM   1170 C C     . LEU A 1 183 ? 128.685 139.916 154.702 1.00 75.17  ? 183 LEU C C     1 
ATOM   1171 O O     . LEU A 1 183 ? 127.868 140.673 154.167 1.00 74.72  ? 183 LEU C O     1 
ATOM   1172 C CB    . LEU A 1 183 ? 129.113 140.249 157.152 1.00 69.77  ? 183 LEU C CB    1 
ATOM   1173 C CG    . LEU A 1 183 ? 128.687 140.022 158.605 1.00 71.54  ? 183 LEU C CG    1 
ATOM   1174 C CD1   . LEU A 1 183 ? 129.386 141.012 159.518 1.00 70.40  ? 183 LEU C CD1   1 
ATOM   1175 C CD2   . LEU A 1 183 ? 127.179 140.125 158.766 1.00 69.92  ? 183 LEU C CD2   1 
ATOM   1176 N N     . GLU A 1 184 ? 129.810 139.542 154.090 1.00 76.50  ? 184 GLU C N     1 
ATOM   1177 C CA    . GLU A 1 184 ? 130.091 140.007 152.736 1.00 75.34  ? 184 GLU C CA    1 
ATOM   1178 C C     . GLU A 1 184 ? 129.047 139.496 151.753 1.00 72.58  ? 184 GLU C C     1 
ATOM   1179 O O     . GLU A 1 184 ? 128.598 140.239 150.873 1.00 69.39  ? 184 GLU C O     1 
ATOM   1180 C CB    . GLU A 1 184 ? 131.491 139.569 152.310 1.00 77.93  ? 184 GLU C CB    1 
ATOM   1181 C CG    . GLU A 1 184 ? 132.614 140.166 153.148 1.00 82.68  ? 184 GLU C CG    1 
ATOM   1182 C CD    . GLU A 1 184 ? 132.510 141.673 153.281 1.00 83.38  ? 184 GLU C CD    1 
ATOM   1183 O OE1   . GLU A 1 184 ? 132.059 142.326 152.316 1.00 74.68  ? 184 GLU C OE1   1 
ATOM   1184 O OE2   . GLU A 1 184 ? 132.876 142.204 154.351 1.00 87.44  ? 184 GLU C OE2   1 
ATOM   1185 N N     . ASP A 1 185 ? 128.646 138.230 151.882 1.00 73.82  ? 185 ASP C N     1 
ATOM   1186 C CA    . ASP A 1 185 ? 127.596 137.705 151.014 1.00 72.18  ? 185 ASP C CA    1 
ATOM   1187 C C     . ASP A 1 185 ? 126.288 138.454 151.224 1.00 65.49  ? 185 ASP C C     1 
ATOM   1188 O O     . ASP A 1 185 ? 125.600 138.798 150.257 1.00 63.23  ? 185 ASP C O     1 
ATOM   1189 C CB    . ASP A 1 185 ? 127.398 136.211 151.267 1.00 75.78  ? 185 ASP C CB    1 
ATOM   1190 C CG    . ASP A 1 185 ? 128.701 135.441 151.269 1.00 80.09  ? 185 ASP C CG    1 
ATOM   1191 O OD1   . ASP A 1 185 ? 129.392 135.435 150.228 1.00 81.85  ? 185 ASP C OD1   1 
ATOM   1192 O OD2   . ASP A 1 185 ? 129.032 134.837 152.310 1.00 81.37  ? 185 ASP C OD2   1 
ATOM   1193 N N     . ALA A 1 186 ? 125.927 138.718 152.480 1.00 69.12  ? 186 ALA C N     1 
ATOM   1194 C CA    . ALA A 1 186 ? 124.697 139.447 152.763 1.00 69.66  ? 186 ALA C CA    1 
ATOM   1195 C C     . ALA A 1 186 ? 124.779 140.907 152.338 1.00 61.75  ? 186 ALA C C     1 
ATOM   1196 O O     . ALA A 1 186 ? 123.743 141.571 152.239 1.00 57.86  ? 186 ALA C O     1 
ATOM   1197 C CB    . ALA A 1 186 ? 124.369 139.363 154.254 1.00 67.50  ? 186 ALA C CB    1 
ATOM   1198 N N     . GLN A 1 187 ? 125.982 141.419 152.083 1.00 59.57  ? 187 GLN C N     1 
ATOM   1199 C CA    . GLN A 1 187 ? 126.129 142.816 151.701 1.00 59.80  ? 187 GLN C CA    1 
ATOM   1200 C C     . GLN A 1 187 ? 125.502 143.123 150.347 1.00 60.61  ? 187 GLN C C     1 
ATOM   1201 O O     . GLN A 1 187 ? 125.264 144.297 150.046 1.00 62.41  ? 187 GLN C O     1 
ATOM   1202 C CB    . GLN A 1 187 ? 127.611 143.191 151.684 1.00 69.99  ? 187 GLN C CB    1 
ATOM   1203 C CG    . GLN A 1 187 ? 127.898 144.637 151.319 1.00 68.95  ? 187 GLN C CG    1 
ATOM   1204 C CD    . GLN A 1 187 ? 129.374 144.972 151.403 1.00 73.07  ? 187 GLN C CD    1 
ATOM   1205 O OE1   . GLN A 1 187 ? 130.221 144.081 151.450 1.00 73.04  ? 187 GLN C OE1   1 
ATOM   1206 N NE2   . GLN A 1 187 ? 129.689 146.261 151.420 1.00 80.96  ? 187 GLN C NE2   1 
ATOM   1207 N N     . TRP A 1 188 ? 125.227 142.108 149.528 1.00 59.57  ? 188 TRP C N     1 
ATOM   1208 C CA    . TRP A 1 188 ? 124.752 142.311 148.165 1.00 57.92  ? 188 TRP C CA    1 
ATOM   1209 C C     . TRP A 1 188 ? 123.304 141.885 147.963 1.00 54.38  ? 188 TRP C C     1 
ATOM   1210 O O     . TRP A 1 188 ? 122.858 141.781 146.816 1.00 56.91  ? 188 TRP C O     1 
ATOM   1211 C CB    . TRP A 1 188 ? 125.652 141.562 147.181 1.00 58.72  ? 188 TRP C CB    1 
ATOM   1212 C CG    . TRP A 1 188 ? 127.043 142.101 147.125 1.00 63.70  ? 188 TRP C CG    1 
ATOM   1213 C CD1   . TRP A 1 188 ? 128.199 141.399 147.290 1.00 65.44  ? 188 TRP C CD1   1 
ATOM   1214 C CD2   . TRP A 1 188 ? 127.428 143.460 146.888 1.00 63.93  ? 188 TRP C CD2   1 
ATOM   1215 N NE1   . TRP A 1 188 ? 129.281 142.237 147.171 1.00 69.19  ? 188 TRP C NE1   1 
ATOM   1216 C CE2   . TRP A 1 188 ? 128.833 143.508 146.924 1.00 68.02  ? 188 TRP C CE2   1 
ATOM   1217 C CE3   . TRP A 1 188 ? 126.720 144.640 146.649 1.00 62.52  ? 188 TRP C CE3   1 
ATOM   1218 C CZ2   . TRP A 1 188 ? 129.543 144.687 146.730 1.00 70.63  ? 188 TRP C CZ2   1 
ATOM   1219 C CZ3   . TRP A 1 188 ? 127.427 145.808 146.456 1.00 67.82  ? 188 TRP C CZ3   1 
ATOM   1220 C CH2   . TRP A 1 188 ? 128.823 145.824 146.498 1.00 71.49  ? 188 TRP C CH2   1 
ATOM   1221 N N     . PHE A 1 189 ? 122.562 141.632 149.033 1.00 46.80  ? 189 PHE C N     1 
ATOM   1222 C CA    . PHE A 1 189 ? 121.148 141.327 148.889 1.00 42.50  ? 189 PHE C CA    1 
ATOM   1223 C C     . PHE A 1 189 ? 120.406 142.564 148.388 1.00 43.44  ? 189 PHE C C     1 
ATOM   1224 O O     . PHE A 1 189 ? 120.733 143.685 148.790 1.00 44.88  ? 189 PHE C O     1 
ATOM   1225 C CB    . PHE A 1 189 ? 120.570 140.867 150.226 1.00 43.88  ? 189 PHE C CB    1 
ATOM   1226 C CG    . PHE A 1 189 ? 119.099 140.573 150.188 1.00 41.44  ? 189 PHE C CG    1 
ATOM   1227 C CD1   . PHE A 1 189 ? 118.171 141.591 150.297 1.00 39.02  ? 189 PHE C CD1   1 
ATOM   1228 C CD2   . PHE A 1 189 ? 118.646 139.275 150.053 1.00 40.90  ? 189 PHE C CD2   1 
ATOM   1229 C CE1   . PHE A 1 189 ? 116.826 141.323 150.264 1.00 36.37  ? 189 PHE C CE1   1 
ATOM   1230 C CE2   . PHE A 1 189 ? 117.299 139.001 150.021 1.00 40.73  ? 189 PHE C CE2   1 
ATOM   1231 C CZ    . PHE A 1 189 ? 116.387 140.027 150.127 1.00 40.16  ? 189 PHE C CZ    1 
ATOM   1232 N N     . PRO A 1 190 ? 119.396 142.404 147.513 1.00 44.04  ? 190 PRO C N     1 
ATOM   1233 C CA    . PRO A 1 190 ? 118.873 141.178 146.897 1.00 44.27  ? 190 PRO C CA    1 
ATOM   1234 C C     . PRO A 1 190 ? 119.718 140.656 145.740 1.00 47.46  ? 190 PRO C C     1 
ATOM   1235 O O     . PRO A 1 190 ? 120.486 141.411 145.148 1.00 51.67  ? 190 PRO C O     1 
ATOM   1236 C CB    . PRO A 1 190 ? 117.493 141.607 146.399 1.00 38.96  ? 190 PRO C CB    1 
ATOM   1237 C CG    . PRO A 1 190 ? 117.634 143.044 146.118 1.00 40.35  ? 190 PRO C CG    1 
ATOM   1238 C CD    . PRO A 1 190 ? 118.601 143.582 147.129 1.00 41.90  ? 190 PRO C CD    1 
ATOM   1239 N N     . TYR A 1 191 ? 119.563 139.371 145.424 1.00 46.38  ? 191 TYR C N     1 
ATOM   1240 C CA    . TYR A 1 191 ? 120.297 138.728 144.336 1.00 50.28  ? 191 TYR C CA    1 
ATOM   1241 C C     . TYR A 1 191 ? 119.330 138.519 143.175 1.00 52.06  ? 191 TYR C C     1 
ATOM   1242 O O     . TYR A 1 191 ? 118.699 137.470 143.049 1.00 52.26  ? 191 TYR C O     1 
ATOM   1243 C CB    . TYR A 1 191 ? 120.912 137.415 144.802 1.00 52.11  ? 191 TYR C CB    1 
ATOM   1244 C CG    . TYR A 1 191 ? 122.079 137.596 145.743 1.00 53.71  ? 191 TYR C CG    1 
ATOM   1245 C CD1   . TYR A 1 191 ? 123.368 137.745 145.255 1.00 56.38  ? 191 TYR C CD1   1 
ATOM   1246 C CD2   . TYR A 1 191 ? 121.892 137.629 147.116 1.00 55.54  ? 191 TYR C CD2   1 
ATOM   1247 C CE1   . TYR A 1 191 ? 124.437 137.915 146.106 1.00 55.56  ? 191 TYR C CE1   1 
ATOM   1248 C CE2   . TYR A 1 191 ? 122.956 137.797 147.974 1.00 57.02  ? 191 TYR C CE2   1 
ATOM   1249 C CZ    . TYR A 1 191 ? 124.225 137.942 147.463 1.00 56.75  ? 191 TYR C CZ    1 
ATOM   1250 O OH    . TYR A 1 191 ? 125.289 138.109 148.315 1.00 65.50  ? 191 TYR C OH    1 
ATOM   1251 N N     . LEU A 1 192 ? 119.225 139.528 142.316 1.00 51.66  ? 192 LEU C N     1 
ATOM   1252 C CA    . LEU A 1 192 ? 118.300 139.529 141.194 1.00 51.65  ? 192 LEU C CA    1 
ATOM   1253 C C     . LEU A 1 192 ? 119.066 139.464 139.877 1.00 52.01  ? 192 LEU C C     1 
ATOM   1254 O O     . LEU A 1 192 ? 120.298 139.511 139.837 1.00 55.00  ? 192 LEU C O     1 
ATOM   1255 C CB    . LEU A 1 192 ? 117.407 140.770 141.242 1.00 50.75  ? 192 LEU C CB    1 
ATOM   1256 C CG    . LEU A 1 192 ? 116.530 140.936 142.481 1.00 50.27  ? 192 LEU C CG    1 
ATOM   1257 C CD1   . LEU A 1 192 ? 115.594 142.109 142.293 1.00 44.86  ? 192 LEU C CD1   1 
ATOM   1258 C CD2   . LEU A 1 192 ? 115.745 139.670 142.767 1.00 46.92  ? 192 LEU C CD2   1 
ATOM   1259 N N     . SER A 1 193 ? 118.311 139.361 138.787 1.00 50.37  ? 193 SER C N     1 
ATOM   1260 C CA    . SER A 1 193 ? 118.893 139.238 137.462 1.00 51.43  ? 193 SER C CA    1 
ATOM   1261 C C     . SER A 1 193 ? 119.548 140.552 137.037 1.00 50.18  ? 193 SER C C     1 
ATOM   1262 O O     . SER A 1 193 ? 119.417 141.590 137.690 1.00 53.85  ? 193 SER C O     1 
ATOM   1263 C CB    . SER A 1 193 ? 117.823 138.828 136.453 1.00 59.80  ? 193 SER C CB    1 
ATOM   1264 O OG    . SER A 1 193 ? 116.856 139.850 136.299 1.00 59.10  ? 193 SER C OG    1 
ATOM   1265 N N     . GLY A 1 194 ? 120.271 140.492 135.918 1.00 51.66  ? 194 GLY C N     1 
ATOM   1266 C CA    . GLY A 1 194 ? 120.981 141.668 135.444 1.00 57.18  ? 194 GLY C CA    1 
ATOM   1267 C C     . GLY A 1 194 ? 120.052 142.783 135.003 1.00 59.33  ? 194 GLY C C     1 
ATOM   1268 O O     . GLY A 1 194 ? 120.291 143.957 135.303 1.00 61.27  ? 194 GLY C O     1 
ATOM   1269 N N     . ASP A 1 195 ? 118.988 142.438 134.276 1.00 57.18  ? 195 ASP C N     1 
ATOM   1270 C CA    . ASP A 1 195 ? 118.064 143.463 133.803 1.00 58.90  ? 195 ASP C CA    1 
ATOM   1271 C C     . ASP A 1 195 ? 117.399 144.177 134.971 1.00 56.62  ? 195 ASP C C     1 
ATOM   1272 O O     . ASP A 1 195 ? 117.126 145.383 134.900 1.00 51.87  ? 195 ASP C O     1 
ATOM   1273 C CB    . ASP A 1 195 ? 117.015 142.840 132.882 1.00 57.03  ? 195 ASP C CB    1 
ATOM   1274 C CG    . ASP A 1 195 ? 116.816 143.631 131.603 1.00 65.02  ? 195 ASP C CG    1 
ATOM   1275 O OD1   . ASP A 1 195 ? 117.193 144.821 131.567 1.00 67.58  ? 195 ASP C OD1   1 
ATOM   1276 O OD2   . ASP A 1 195 ? 116.284 143.060 130.628 1.00 60.34  ? 195 ASP C OD2   1 
ATOM   1277 N N     . SER A 1 196 ? 117.133 143.451 136.058 1.00 52.37  ? 196 SER C N     1 
ATOM   1278 C CA    . SER A 1 196 ? 116.586 144.087 137.249 1.00 44.09  ? 196 SER C CA    1 
ATOM   1279 C C     . SER A 1 196 ? 117.519 145.181 137.750 1.00 45.86  ? 196 SER C C     1 
ATOM   1280 O O     . SER A 1 196 ? 117.081 146.297 138.048 1.00 51.77  ? 196 SER C O     1 
ATOM   1281 C CB    . SER A 1 196 ? 116.343 143.042 138.336 1.00 44.51  ? 196 SER C CB    1 
ATOM   1282 O OG    . SER A 1 196 ? 115.075 142.433 138.181 1.00 44.28  ? 196 SER C OG    1 
ATOM   1283 N N     . TYR A 1 197 ? 118.816 144.885 137.836 1.00 46.14  ? 197 TYR C N     1 
ATOM   1284 C CA    . TYR A 1 197 ? 119.767 145.913 138.239 1.00 45.23  ? 197 TYR C CA    1 
ATOM   1285 C C     . TYR A 1 197 ? 119.780 147.061 137.242 1.00 50.68  ? 197 TYR C C     1 
ATOM   1286 O O     . TYR A 1 197 ? 119.843 148.232 137.633 1.00 52.39  ? 197 TYR C O     1 
ATOM   1287 C CB    . TYR A 1 197 ? 121.171 145.327 138.379 1.00 47.30  ? 197 TYR C CB    1 
ATOM   1288 C CG    . TYR A 1 197 ? 122.231 146.386 138.591 1.00 49.33  ? 197 TYR C CG    1 
ATOM   1289 C CD1   . TYR A 1 197 ? 122.522 146.862 139.860 1.00 48.72  ? 197 TYR C CD1   1 
ATOM   1290 C CD2   . TYR A 1 197 ? 122.930 146.921 137.519 1.00 58.76  ? 197 TYR C CD2   1 
ATOM   1291 C CE1   . TYR A 1 197 ? 123.484 147.833 140.055 1.00 52.75  ? 197 TYR C CE1   1 
ATOM   1292 C CE2   . TYR A 1 197 ? 123.891 147.893 137.705 1.00 54.84  ? 197 TYR C CE2   1 
ATOM   1293 C CZ    . TYR A 1 197 ? 124.164 148.345 138.973 1.00 53.54  ? 197 TYR C CZ    1 
ATOM   1294 O OH    . TYR A 1 197 ? 125.123 149.313 139.158 1.00 54.97  ? 197 TYR C OH    1 
ATOM   1295 N N     . ARG A 1 198 ? 119.726 146.746 135.947 1.00 52.24  ? 198 ARG C N     1 
ATOM   1296 C CA    . ARG A 1 198 ? 119.780 147.800 134.940 1.00 57.22  ? 198 ARG C CA    1 
ATOM   1297 C C     . ARG A 1 198 ? 118.618 148.770 135.101 1.00 52.28  ? 198 ARG C C     1 
ATOM   1298 O O     . ARG A 1 198 ? 118.790 149.986 134.958 1.00 53.11  ? 198 ARG C O     1 
ATOM   1299 C CB    . ARG A 1 198 ? 119.773 147.193 133.538 1.00 64.60  ? 198 ARG C CB    1 
ATOM   1300 C CG    . ARG A 1 198 ? 121.139 146.737 133.037 1.00 73.46  ? 198 ARG C CG    1 
ATOM   1301 C CD    . ARG A 1 198 ? 121.572 147.500 131.792 1.00 86.45  ? 198 ARG C CD    1 
ATOM   1302 N NE    . ARG A 1 198 ? 122.460 146.709 130.949 1.00 90.71  ? 198 ARG C NE    1 
ATOM   1303 C CZ    . ARG A 1 198 ? 123.440 147.207 130.205 1.00 93.39  ? 198 ARG C CZ    1 
ATOM   1304 N NH1   . ARG A 1 198 ? 123.705 148.503 130.181 1.00 97.84  ? 198 ARG C NH1   1 
ATOM   1305 N NH2   . ARG A 1 198 ? 124.170 146.383 129.459 1.00 94.18  ? 198 ARG C NH2   1 
ATOM   1306 N N     . ALA A 1 199 ? 117.424 148.252 135.391 1.00 44.11  ? 199 ALA C N     1 
ATOM   1307 C CA    . ALA A 1 199 ? 116.254 149.118 135.493 1.00 39.87  ? 199 ALA C CA    1 
ATOM   1308 C C     . ALA A 1 199 ? 116.311 149.990 136.743 1.00 43.22  ? 199 ALA C C     1 
ATOM   1309 O O     . ALA A 1 199 ? 116.076 151.201 136.675 1.00 44.09  ? 199 ALA C O     1 
ATOM   1310 C CB    . ALA A 1 199 ? 114.982 148.276 135.485 1.00 43.26  ? 199 ALA C CB    1 
ATOM   1311 N N     . CYS A 1 200 ? 116.622 149.392 137.896 1.00 49.79  ? 200 CYS C N     1 
ATOM   1312 C CA    . CYS A 1 200 ? 116.641 150.090 139.184 1.00 43.07  ? 200 CYS C CA    1 
ATOM   1313 C C     . CYS A 1 200 ? 117.980 149.837 139.862 1.00 43.72  ? 200 CYS C C     1 
ATOM   1314 O O     . CYS A 1 200 ? 118.091 148.964 140.732 1.00 41.45  ? 200 CYS C O     1 
ATOM   1315 C CB    . CYS A 1 200 ? 115.494 149.634 140.083 1.00 36.58  ? 200 CYS C CB    1 
ATOM   1316 S SG    . CYS A 1 200 ? 113.857 150.090 139.495 1.00 63.94  ? 200 CYS C SG    1 
ATOM   1317 N N     . PRO A 1 201 ? 119.022 150.581 139.489 1.00 45.14  ? 201 PRO C N     1 
ATOM   1318 C CA    . PRO A 1 201 ? 120.340 150.334 140.095 1.00 46.37  ? 201 PRO C CA    1 
ATOM   1319 C C     . PRO A 1 201 ? 120.377 150.572 141.593 1.00 44.21  ? 201 PRO C C     1 
ATOM   1320 O O     . PRO A 1 201 ? 121.139 149.901 142.299 1.00 44.15  ? 201 PRO C O     1 
ATOM   1321 C CB    . PRO A 1 201 ? 121.254 151.310 139.344 1.00 51.81  ? 201 PRO C CB    1 
ATOM   1322 C CG    . PRO A 1 201 ? 120.352 152.390 138.872 1.00 53.78  ? 201 PRO C CG    1 
ATOM   1323 C CD    . PRO A 1 201 ? 119.039 151.739 138.580 1.00 50.53  ? 201 PRO C CD    1 
ATOM   1324 N N     . GLY A 1 202 ? 119.578 151.504 142.102 1.00 42.51  ? 202 GLY C N     1 
ATOM   1325 C CA    . GLY A 1 202 ? 119.647 151.905 143.492 1.00 47.11  ? 202 GLY C CA    1 
ATOM   1326 C C     . GLY A 1 202 ? 118.927 151.018 144.477 1.00 42.80  ? 202 GLY C C     1 
ATOM   1327 O O     . GLY A 1 202 ? 118.931 151.319 145.672 1.00 41.87  ? 202 GLY C O     1 
ATOM   1328 N N     . LEU A 1 203 ? 118.301 149.938 144.020 1.00 40.63  ? 203 LEU C N     1 
ATOM   1329 C CA    . LEU A 1 203 ? 117.585 149.019 144.893 1.00 36.90  ? 203 LEU C CA    1 
ATOM   1330 C C     . LEU A 1 203 ? 118.020 147.572 144.743 1.00 38.57  ? 203 LEU C C     1 
ATOM   1331 O O     . LEU A 1 203 ? 117.857 146.795 145.685 1.00 34.35  ? 203 LEU C O     1 
ATOM   1332 C CB    . LEU A 1 203 ? 116.075 149.095 144.628 1.00 33.44  ? 203 LEU C CB    1 
ATOM   1333 C CG    . LEU A 1 203 ? 115.441 150.483 144.682 1.00 31.70  ? 203 LEU C CG    1 
ATOM   1334 C CD1   . LEU A 1 203 ? 114.164 150.508 143.864 1.00 34.01  ? 203 LEU C CD1   1 
ATOM   1335 C CD2   . LEU A 1 203 ? 115.169 150.886 146.116 1.00 30.74  ? 203 LEU C CD2   1 
ATOM   1336 N N     . VAL A 1 204 ? 118.572 147.193 143.595 1.00 39.82  ? 204 VAL C N     1 
ATOM   1337 C CA    . VAL A 1 204 ? 118.882 145.805 143.282 1.00 40.20  ? 204 VAL C CA    1 
ATOM   1338 C C     . VAL A 1 204 ? 120.359 145.555 143.537 1.00 42.06  ? 204 VAL C C     1 
ATOM   1339 O O     . VAL A 1 204 ? 121.215 146.335 143.103 1.00 43.82  ? 204 VAL C O     1 
ATOM   1340 C CB    . VAL A 1 204 ? 118.517 145.474 141.826 1.00 41.91  ? 204 VAL C CB    1 
ATOM   1341 C CG1   . VAL A 1 204 ? 118.982 144.077 141.470 1.00 44.29  ? 204 VAL C CG1   1 
ATOM   1342 C CG2   . VAL A 1 204 ? 117.023 145.617 141.618 1.00 41.78  ? 204 VAL C CG2   1 
ATOM   1343 N N     . GLY A 1 205 ? 120.656 144.467 144.238 1.00 42.20  ? 205 GLY C N     1 
ATOM   1344 C CA    . GLY A 1 205 ? 122.025 144.056 144.470 1.00 45.59  ? 205 GLY C CA    1 
ATOM   1345 C C     . GLY A 1 205 ? 122.472 143.021 143.461 1.00 48.95  ? 205 GLY C C     1 
ATOM   1346 O O     . GLY A 1 205 ? 122.527 143.300 142.262 1.00 57.96  ? 205 GLY C O     1 
ATOM   1347 N N     . GLY A 1 206 ? 122.790 141.825 143.928 1.00 50.74  ? 206 GLY C N     1 
ATOM   1348 C CA    . GLY A 1 206 ? 123.179 140.759 143.037 1.00 52.85  ? 206 GLY C CA    1 
ATOM   1349 C C     . GLY A 1 206 ? 124.596 140.925 142.528 1.00 60.27  ? 206 GLY C C     1 
ATOM   1350 O O     . GLY A 1 206 ? 125.350 141.807 142.944 1.00 64.32  ? 206 GLY C O     1 
ATOM   1351 N N     . TYR A 1 207 ? 124.955 140.047 141.591 1.00 66.58  ? 207 TYR C N     1 
ATOM   1352 C CA    . TYR A 1 207 ? 126.317 140.047 141.067 1.00 73.29  ? 207 TYR C CA    1 
ATOM   1353 C C     . TYR A 1 207 ? 126.642 141.357 140.361 1.00 70.54  ? 207 TYR C C     1 
ATOM   1354 O O     . TYR A 1 207 ? 127.743 141.896 140.518 1.00 72.75  ? 207 TYR C O     1 
ATOM   1355 C CB    . TYR A 1 207 ? 126.512 138.867 140.116 1.00 74.23  ? 207 TYR C CB    1 
ATOM   1356 C CG    . TYR A 1 207 ? 127.595 139.092 139.086 1.00 77.23  ? 207 TYR C CG    1 
ATOM   1357 C CD1   . TYR A 1 207 ? 128.927 138.848 139.387 1.00 79.81  ? 207 TYR C CD1   1 
ATOM   1358 C CD2   . TYR A 1 207 ? 127.285 139.545 137.811 1.00 82.61  ? 207 TYR C CD2   1 
ATOM   1359 C CE1   . TYR A 1 207 ? 129.921 139.052 138.450 1.00 82.24  ? 207 TYR C CE1   1 
ATOM   1360 C CE2   . TYR A 1 207 ? 128.272 139.751 136.867 1.00 88.47  ? 207 TYR C CE2   1 
ATOM   1361 C CZ    . TYR A 1 207 ? 129.587 139.503 137.192 1.00 88.12  ? 207 TYR C CZ    1 
ATOM   1362 O OH    . TYR A 1 207 ? 130.573 139.707 136.255 1.00 87.54  ? 207 TYR C OH    1 
ATOM   1363 N N     . PHE A 1 208 ? 125.701 141.882 139.574 1.00 63.57  ? 208 PHE C N     1 
ATOM   1364 C CA    . PHE A 1 208 ? 125.987 143.074 138.783 1.00 62.13  ? 208 PHE C CA    1 
ATOM   1365 C C     . PHE A 1 208 ? 126.257 144.279 139.673 1.00 62.29  ? 208 PHE C C     1 
ATOM   1366 O O     . PHE A 1 208 ? 127.100 145.123 139.346 1.00 69.63  ? 208 PHE C O     1 
ATOM   1367 C CB    . PHE A 1 208 ? 124.832 143.351 137.826 1.00 63.95  ? 208 PHE C CB    1 
ATOM   1368 C CG    . PHE A 1 208 ? 124.882 142.527 136.574 1.00 76.53  ? 208 PHE C CG    1 
ATOM   1369 C CD1   . PHE A 1 208 ? 125.593 142.962 135.469 1.00 80.98  ? 208 PHE C CD1   1 
ATOM   1370 C CD2   . PHE A 1 208 ? 124.233 141.307 136.507 1.00 78.14  ? 208 PHE C CD2   1 
ATOM   1371 C CE1   . PHE A 1 208 ? 125.646 142.201 134.317 1.00 83.62  ? 208 PHE C CE1   1 
ATOM   1372 C CE2   . PHE A 1 208 ? 124.282 140.543 135.359 1.00 79.95  ? 208 PHE C CE2   1 
ATOM   1373 C CZ    . PHE A 1 208 ? 124.989 140.990 134.263 1.00 82.88  ? 208 PHE C CZ    1 
ATOM   1374 N N     . ALA A 1 209 ? 125.550 144.387 140.797 1.00 59.94  ? 209 ALA C N     1 
ATOM   1375 C CA    . ALA A 1 209 ? 125.850 145.456 141.742 1.00 61.00  ? 209 ALA C CA    1 
ATOM   1376 C C     . ALA A 1 209 ? 127.270 145.323 142.275 1.00 68.74  ? 209 ALA C C     1 
ATOM   1377 O O     . ALA A 1 209 ? 127.987 146.321 142.414 1.00 74.40  ? 209 ALA C O     1 
ATOM   1378 C CB    . ALA A 1 209 ? 124.841 145.442 142.888 1.00 58.51  ? 209 ALA C CB    1 
ATOM   1379 N N     . LYS A 1 210 ? 127.693 144.094 142.578 1.00 70.57  ? 210 LYS C N     1 
ATOM   1380 C CA    . LYS A 1 210 ? 129.062 143.869 143.027 1.00 72.92  ? 210 LYS C CA    1 
ATOM   1381 C C     . LYS A 1 210 ? 130.063 144.290 141.959 1.00 75.99  ? 210 LYS C C     1 
ATOM   1382 O O     . LYS A 1 210 ? 131.065 144.949 142.258 1.00 77.20  ? 210 LYS C O     1 
ATOM   1383 C CB    . LYS A 1 210 ? 129.251 142.396 143.390 1.00 69.05  ? 210 LYS C CB    1 
ATOM   1384 C CG    . LYS A 1 210 ? 130.656 141.864 143.168 1.00 71.01  ? 210 LYS C CG    1 
ATOM   1385 C CD    . LYS A 1 210 ? 130.862 140.541 143.883 1.00 69.77  ? 210 LYS C CD    1 
ATOM   1386 C CE    . LYS A 1 210 ? 132.021 139.760 143.286 1.00 67.08  ? 210 LYS C CE    1 
ATOM   1387 N NZ    . LYS A 1 210 ? 133.220 140.611 143.054 1.00 69.80  ? 210 LYS C NZ    1 
ATOM   1388 N N     . LYS A 1 211 ? 129.803 143.919 140.704 1.00 77.17  ? 211 LYS C N     1 
ATOM   1389 C CA    . LYS A 1 211 ? 130.696 144.301 139.616 1.00 74.47  ? 211 LYS C CA    1 
ATOM   1390 C C     . LYS A 1 211 ? 130.782 145.815 139.486 1.00 70.50  ? 211 LYS C C     1 
ATOM   1391 O O     . LYS A 1 211 ? 131.872 146.370 139.311 1.00 73.17  ? 211 LYS C O     1 
ATOM   1392 C CB    . LYS A 1 211 ? 130.213 143.674 138.309 1.00 79.15  ? 211 LYS C CB    1 
ATOM   1393 C CG    . LYS A 1 211 ? 130.963 144.129 137.070 1.00 82.89  ? 211 LYS C CG    1 
ATOM   1394 C CD    . LYS A 1 211 ? 130.417 143.456 135.823 1.00 83.38  ? 211 LYS C CD    1 
ATOM   1395 C CE    . LYS A 1 211 ? 131.158 143.911 134.579 1.00 86.20  ? 211 LYS C CE    1 
ATOM   1396 N NZ    . LYS A 1 211 ? 130.723 143.164 133.368 1.00 89.30  ? 211 LYS C NZ    1 
ATOM   1397 N N     . ALA A 1 212 ? 129.642 146.501 139.568 1.00 67.30  ? 212 ALA C N     1 
ATOM   1398 C CA    . ALA A 1 212 ? 129.654 147.955 139.470 1.00 71.40  ? 212 ALA C CA    1 
ATOM   1399 C C     . ALA A 1 212 ? 130.442 148.574 140.616 1.00 79.03  ? 212 ALA C C     1 
ATOM   1400 O O     . ALA A 1 212 ? 131.222 149.511 140.409 1.00 81.53  ? 212 ALA C O     1 
ATOM   1401 C CB    . ALA A 1 212 ? 128.225 148.492 139.452 1.00 73.04  ? 212 ALA C CB    1 
ATOM   1402 N N     . ALA A 1 213 ? 130.249 148.069 141.835 1.00 84.95  ? 213 ALA C N     1 
ATOM   1403 C CA    . ALA A 1 213 ? 130.998 148.591 142.974 1.00 89.16  ? 213 ALA C CA    1 
ATOM   1404 C C     . ALA A 1 213 ? 132.452 148.141 142.929 1.00 90.30  ? 213 ALA C C     1 
ATOM   1405 O O     . ALA A 1 213 ? 133.368 148.943 143.143 1.00 87.94  ? 213 ALA C O     1 
ATOM   1406 C CB    . ALA A 1 213 ? 130.337 148.151 144.280 1.00 82.25  ? 213 ALA C CB    1 
ATOM   1407 N N     . ALA A 1 214 ? 132.686 146.861 142.644 1.00 88.13  ? 214 ALA C N     1 
ATOM   1408 C CA    . ALA A 1 214 ? 134.043 146.335 142.578 1.00 85.89  ? 214 ALA C CA    1 
ATOM   1409 C C     . ALA A 1 214 ? 134.641 146.588 141.201 1.00 91.60  ? 214 ALA C C     1 
ATOM   1410 O O     . ALA A 1 214 ? 135.127 145.660 140.547 1.00 92.45  ? 214 ALA C O     1 
ATOM   1411 C CB    . ALA A 1 214 ? 134.056 144.839 142.900 1.00 80.65  ? 214 ALA C CB    1 
ATOM   1412 N N     . GLY A 1 215 ? 134.614 147.839 140.760 1.00 95.05  ? 215 GLY C N     1 
ATOM   1413 C CA    . GLY A 1 215 ? 135.109 148.177 139.439 1.00 97.93  ? 215 GLY C CA    1 
ATOM   1414 C C     . GLY A 1 215 ? 134.990 149.665 139.203 1.00 101.53 ? 215 GLY C C     1 
ATOM   1415 O O     . GLY A 1 215 ? 134.568 150.428 140.078 1.00 98.72  ? 215 GLY C O     1 
ATOM   1416 N N     . GLU A 1 216 ? 135.369 150.068 137.993 1.00 105.08 ? 216 GLU C N     1 
ATOM   1417 C CA    . GLU A 1 216 ? 135.364 151.482 137.642 1.00 107.45 ? 216 GLU C CA    1 
ATOM   1418 C C     . GLU A 1 216 ? 133.973 152.068 137.843 1.00 103.02 ? 216 GLU C C     1 
ATOM   1419 O O     . GLU A 1 216 ? 132.969 151.469 137.449 1.00 98.97  ? 216 GLU C O     1 
ATOM   1420 C CB    . GLU A 1 216 ? 135.817 151.666 136.193 1.00 106.15 ? 216 GLU C CB    1 
ATOM   1421 C CG    . GLU A 1 216 ? 136.279 153.077 135.861 1.00 105.05 ? 216 GLU C CG    1 
ATOM   1422 C CD    . GLU A 1 216 ? 137.609 153.423 136.505 1.00 102.58 ? 216 GLU C CD    1 
ATOM   1423 O OE1   . GLU A 1 216 ? 138.277 152.504 137.024 1.00 100.64 ? 216 GLU C OE1   1 
ATOM   1424 O OE2   . GLU A 1 216 ? 137.987 154.613 136.490 1.00 102.81 ? 216 GLU C OE2   1 
ATOM   1425 N N     . ARG A 1 217 ? 133.918 153.245 138.461 1.00 102.16 ? 217 ARG C N     1 
ATOM   1426 C CA    . ARG A 1 217 ? 132.665 153.909 138.789 1.00 106.43 ? 217 ARG C CA    1 
ATOM   1427 C C     . ARG A 1 217 ? 132.554 155.211 138.008 1.00 109.69 ? 217 ARG C C     1 
ATOM   1428 O O     . ARG A 1 217 ? 133.491 156.017 138.000 1.00 110.37 ? 217 ARG C O     1 
ATOM   1429 C CB    . ARG A 1 217 ? 132.571 154.189 140.291 1.00 106.06 ? 217 ARG C CB    1 
ATOM   1430 C CG    . ARG A 1 217 ? 133.016 153.034 141.178 1.00 104.38 ? 217 ARG C CG    1 
ATOM   1431 C CD    . ARG A 1 217 ? 132.894 153.393 142.652 1.00 103.01 ? 217 ARG C CD    1 
ATOM   1432 N NE    . ARG A 1 217 ? 133.287 152.289 143.521 1.00 101.78 ? 217 ARG C NE    1 
ATOM   1433 C CZ    . ARG A 1 217 ? 132.951 152.182 144.800 1.00 96.54  ? 217 ARG C CZ    1 
ATOM   1434 N NH1   . ARG A 1 217 ? 132.217 153.104 145.403 1.00 93.90  ? 217 ARG C NH1   1 
ATOM   1435 N NH2   . ARG A 1 217 ? 133.363 151.124 145.493 1.00 95.33  ? 217 ARG C NH2   1 
ATOM   1436 N N     . GLY A 1 218 ? 131.409 155.410 137.353 1.00 111.55 ? 218 GLY C N     1 
ATOM   1437 C CA    . GLY A 1 218 ? 131.118 156.644 136.660 1.00 113.54 ? 218 GLY C CA    1 
ATOM   1438 C C     . GLY A 1 218 ? 130.314 157.605 137.525 1.00 119.47 ? 218 GLY C C     1 
ATOM   1439 O O     . GLY A 1 218 ? 129.958 157.322 138.666 1.00 117.53 ? 218 GLY C O     1 
ATOM   1440 N N     . LYS A 1 219 ? 130.034 158.776 136.950 1.00 125.49 ? 219 LYS C N     1 
ATOM   1441 C CA    . LYS A 1 219 ? 129.244 159.771 137.670 1.00 127.06 ? 219 LYS C CA    1 
ATOM   1442 C C     . LYS A 1 219 ? 127.819 159.282 137.901 1.00 124.25 ? 219 LYS C C     1 
ATOM   1443 O O     . LYS A 1 219 ? 127.260 159.473 138.987 1.00 116.88 ? 219 LYS C O     1 
ATOM   1444 C CB    . LYS A 1 219 ? 129.238 161.097 136.911 1.00 128.99 ? 219 LYS C CB    1 
ATOM   1445 C CG    . LYS A 1 219 ? 128.739 162.265 137.747 1.00 127.64 ? 219 LYS C CG    1 
ATOM   1446 C CD    . LYS A 1 219 ? 128.809 163.578 136.989 1.00 130.04 ? 219 LYS C CD    1 
ATOM   1447 C CE    . LYS A 1 219 ? 128.001 164.658 137.690 1.00 131.73 ? 219 LYS C CE    1 
ATOM   1448 N NZ    . LYS A 1 219 ? 128.091 165.968 136.993 1.00 138.89 ? 219 LYS C NZ    1 
ATOM   1449 N N     . ASN A 1 220 ? 127.216 158.650 136.893 1.00 127.18 ? 220 ASN C N     1 
ATOM   1450 C CA    . ASN A 1 220 ? 125.863 158.108 137.011 1.00 126.47 ? 220 ASN C CA    1 
ATOM   1451 C C     . ASN A 1 220 ? 125.899 156.753 137.721 1.00 124.34 ? 220 ASN C C     1 
ATOM   1452 O O     . ASN A 1 220 ? 125.463 155.725 137.203 1.00 123.94 ? 220 ASN C O     1 
ATOM   1453 C CB    . ASN A 1 220 ? 125.221 157.994 135.634 1.00 126.26 ? 220 ASN C CB    1 
ATOM   1454 C CG    . ASN A 1 220 ? 124.655 159.310 135.142 1.00 134.32 ? 220 ASN C CG    1 
ATOM   1455 O OD1   . ASN A 1 220 ? 124.065 160.071 135.909 1.00 139.58 ? 220 ASN C OD1   1 
ATOM   1456 N ND2   . ASN A 1 220 ? 124.834 159.587 133.855 1.00 135.35 ? 220 ASN C ND2   1 
ATOM   1457 N N     . TYR A 1 221 ? 126.436 156.772 138.937 1.00 115.62 ? 221 TYR C N     1 
ATOM   1458 C CA    . TYR A 1 221 ? 126.600 155.575 139.750 1.00 105.93 ? 221 TYR C CA    1 
ATOM   1459 C C     . TYR A 1 221 ? 125.674 155.657 140.954 1.00 96.19  ? 221 TYR C C     1 
ATOM   1460 O O     . TYR A 1 221 ? 125.712 156.637 141.706 1.00 93.27  ? 221 TYR C O     1 
ATOM   1461 C CB    . TYR A 1 221 ? 128.053 155.420 140.202 1.00 104.57 ? 221 TYR C CB    1 
ATOM   1462 C CG    . TYR A 1 221 ? 128.313 154.169 141.007 1.00 98.20  ? 221 TYR C CG    1 
ATOM   1463 C CD1   . TYR A 1 221 ? 128.525 152.950 140.379 1.00 92.54  ? 221 TYR C CD1   1 
ATOM   1464 C CD2   . TYR A 1 221 ? 128.353 154.208 142.393 1.00 96.81  ? 221 TYR C CD2   1 
ATOM   1465 C CE1   . TYR A 1 221 ? 128.765 151.804 141.109 1.00 87.55  ? 221 TYR C CE1   1 
ATOM   1466 C CE2   . TYR A 1 221 ? 128.593 153.068 143.131 1.00 98.70  ? 221 TYR C CE2   1 
ATOM   1467 C CZ    . TYR A 1 221 ? 128.798 151.868 142.484 1.00 96.57  ? 221 TYR C CZ    1 
ATOM   1468 O OH    . TYR A 1 221 ? 129.035 150.729 143.217 1.00 94.32  ? 221 TYR C OH    1 
ATOM   1469 N N     . LYS A 1 222 ? 124.850 154.629 141.132 1.00 88.72  ? 222 LYS C N     1 
ATOM   1470 C CA    . LYS A 1 222 ? 123.867 154.576 142.202 1.00 83.50  ? 222 LYS C CA    1 
ATOM   1471 C C     . LYS A 1 222 ? 124.318 153.585 143.264 1.00 75.51  ? 222 LYS C C     1 
ATOM   1472 O O     . LYS A 1 222 ? 124.758 152.475 142.946 1.00 73.65  ? 222 LYS C O     1 
ATOM   1473 C CB    . LYS A 1 222 ? 122.494 154.176 141.661 1.00 73.91  ? 222 LYS C CB    1 
ATOM   1474 C CG    . LYS A 1 222 ? 121.593 155.351 141.328 1.00 72.97  ? 222 LYS C CG    1 
ATOM   1475 C CD    . LYS A 1 222 ? 120.612 155.626 142.451 1.00 71.75  ? 222 LYS C CD    1 
ATOM   1476 C CE    . LYS A 1 222 ? 119.828 156.900 142.201 1.00 73.62  ? 222 LYS C CE    1 
ATOM   1477 N NZ    . LYS A 1 222 ? 118.732 157.082 143.192 1.00 79.86  ? 222 LYS C NZ    1 
ATOM   1478 N N     . LYS A 1 223 ? 124.207 153.990 144.525 1.00 68.16  ? 223 LYS C N     1 
ATOM   1479 C CA    . LYS A 1 223 ? 124.652 153.170 145.642 1.00 65.72  ? 223 LYS C CA    1 
ATOM   1480 C C     . LYS A 1 223 ? 123.503 152.301 146.134 1.00 67.79  ? 223 LYS C C     1 
ATOM   1481 O O     . LYS A 1 223 ? 122.383 152.786 146.320 1.00 66.86  ? 223 LYS C O     1 
ATOM   1482 C CB    . LYS A 1 223 ? 125.178 154.052 146.776 1.00 66.81  ? 223 LYS C CB    1 
ATOM   1483 C CG    . LYS A 1 223 ? 125.884 153.288 147.886 1.00 63.94  ? 223 LYS C CG    1 
ATOM   1484 C CD    . LYS A 1 223 ? 125.800 154.034 149.207 1.00 61.09  ? 223 LYS C CD    1 
ATOM   1485 C CE    . LYS A 1 223 ? 124.449 153.836 149.871 1.00 64.37  ? 223 LYS C CE    1 
ATOM   1486 N NZ    . LYS A 1 223 ? 124.339 154.597 151.144 1.00 68.82  ? 223 LYS C NZ    1 
ATOM   1487 N N     . LEU A 1 224 ? 123.788 151.018 146.340 1.00 62.44  ? 224 LEU C N     1 
ATOM   1488 C CA    . LEU A 1 224 ? 122.766 150.078 146.781 1.00 49.92  ? 224 LEU C CA    1 
ATOM   1489 C C     . LEU A 1 224 ? 122.204 150.495 148.134 1.00 48.48  ? 224 LEU C C     1 
ATOM   1490 O O     . LEU A 1 224 ? 122.955 150.846 149.048 1.00 54.30  ? 224 LEU C O     1 
ATOM   1491 C CB    . LEU A 1 224 ? 123.363 148.674 146.859 1.00 44.99  ? 224 LEU C CB    1 
ATOM   1492 C CG    . LEU A 1 224 ? 122.486 147.567 147.436 1.00 43.05  ? 224 LEU C CG    1 
ATOM   1493 C CD1   . LEU A 1 224 ? 121.197 147.440 146.655 1.00 44.95  ? 224 LEU C CD1   1 
ATOM   1494 C CD2   . LEU A 1 224 ? 123.244 146.256 147.430 1.00 44.94  ? 224 LEU C CD2   1 
ATOM   1495 N N     . ASN A 1 225 ? 120.880 150.457 148.260 1.00 47.05  ? 225 ASN C N     1 
ATOM   1496 C CA    . ASN A 1 225 ? 120.183 150.786 149.504 1.00 47.79  ? 225 ASN C CA    1 
ATOM   1497 C C     . ASN A 1 225 ? 119.329 149.579 149.876 1.00 45.80  ? 225 ASN C C     1 
ATOM   1498 O O     . ASN A 1 225 ? 118.190 149.447 149.425 1.00 46.58  ? 225 ASN C O     1 
ATOM   1499 C CB    . ASN A 1 225 ? 119.334 152.041 149.355 1.00 47.12  ? 225 ASN C CB    1 
ATOM   1500 C CG    . ASN A 1 225 ? 120.093 153.186 148.726 1.00 57.79  ? 225 ASN C CG    1 
ATOM   1501 O OD1   . ASN A 1 225 ? 121.318 153.259 148.819 1.00 63.43  ? 225 ASN C OD1   1 
ATOM   1502 N ND2   . ASN A 1 225 ? 119.367 154.096 148.086 1.00 60.83  ? 225 ASN C ND2   1 
ATOM   1503 N N     . GLN A 1 226 ? 119.882 148.700 150.711 1.00 42.70  ? 226 GLN C N     1 
ATOM   1504 C CA    . GLN A 1 226 ? 119.174 147.478 151.070 1.00 38.47  ? 226 GLN C CA    1 
ATOM   1505 C C     . GLN A 1 226 ? 117.891 147.754 151.836 1.00 37.57  ? 226 GLN C C     1 
ATOM   1506 O O     . GLN A 1 226 ? 117.022 146.880 151.897 1.00 45.54  ? 226 GLN C O     1 
ATOM   1507 C CB    . GLN A 1 226 ? 120.080 146.573 151.903 1.00 38.43  ? 226 GLN C CB    1 
ATOM   1508 C CG    . GLN A 1 226 ? 121.224 145.960 151.125 1.00 38.53  ? 226 GLN C CG    1 
ATOM   1509 C CD    . GLN A 1 226 ? 121.771 144.719 151.792 1.00 43.91  ? 226 GLN C CD    1 
ATOM   1510 O OE1   . GLN A 1 226 ? 121.707 144.579 153.013 1.00 42.87  ? 226 GLN C OE1   1 
ATOM   1511 N NE2   . GLN A 1 226 ? 122.313 143.807 150.994 1.00 46.33  ? 226 GLN C NE2   1 
ATOM   1512 N N     . THR A 1 227 ? 117.744 148.945 152.416 1.00 39.72  ? 227 THR C N     1 
ATOM   1513 C CA    . THR A 1 227 ? 116.605 149.260 153.269 1.00 42.04  ? 227 THR C CA    1 
ATOM   1514 C C     . THR A 1 227 ? 115.765 150.407 152.719 1.00 41.11  ? 227 THR C C     1 
ATOM   1515 O O     . THR A 1 227 ? 115.067 151.080 153.482 1.00 39.72  ? 227 THR C O     1 
ATOM   1516 C CB    . THR A 1 227 ? 117.082 149.588 154.683 1.00 42.67  ? 227 THR C CB    1 
ATOM   1517 O OG1   . THR A 1 227 ? 118.038 150.653 154.632 1.00 45.94  ? 227 THR C OG1   1 
ATOM   1518 C CG2   . THR A 1 227 ? 117.724 148.368 155.313 1.00 39.95  ? 227 THR C CG2   1 
ATOM   1519 N N     . ALA A 1 228 ? 115.818 150.651 151.413 1.00 36.11  ? 228 ALA C N     1 
ATOM   1520 C CA    . ALA A 1 228 ? 114.956 151.663 150.821 1.00 37.03  ? 228 ALA C CA    1 
ATOM   1521 C C     . ALA A 1 228 ? 113.497 151.273 151.007 1.00 37.25  ? 228 ALA C C     1 
ATOM   1522 O O     . ALA A 1 228 ? 113.110 150.123 150.785 1.00 38.79  ? 228 ALA C O     1 
ATOM   1523 C CB    . ALA A 1 228 ? 115.272 151.832 149.336 1.00 39.86  ? 228 ALA C CB    1 
ATOM   1524 N N     . ILE A 1 229 ? 112.682 152.241 151.414 1.00 36.86  ? 229 ILE C N     1 
ATOM   1525 C CA    . ILE A 1 229 ? 111.276 151.983 151.708 1.00 36.25  ? 229 ILE C CA    1 
ATOM   1526 C C     . ILE A 1 229 ? 110.533 151.839 150.386 1.00 34.59  ? 229 ILE C C     1 
ATOM   1527 O O     . ILE A 1 229 ? 110.377 152.808 149.641 1.00 40.48  ? 229 ILE C O     1 
ATOM   1528 C CB    . ILE A 1 229 ? 110.668 153.095 152.568 1.00 39.53  ? 229 ILE C CB    1 
ATOM   1529 C CG1   . ILE A 1 229 ? 111.330 153.114 153.947 1.00 44.05  ? 229 ILE C CG1   1 
ATOM   1530 C CG2   . ILE A 1 229 ? 109.168 152.894 152.703 1.00 39.90  ? 229 ILE C CG2   1 
ATOM   1531 C CD1   . ILE A 1 229 ? 111.059 154.369 154.742 1.00 45.65  ? 229 ILE C CD1   1 
ATOM   1532 N N     . ILE A 1 230 ? 110.081 150.625 150.093 1.00 36.56  ? 230 ILE C N     1 
ATOM   1533 C CA    . ILE A 1 230 ? 109.277 150.308 148.919 1.00 36.48  ? 230 ILE C CA    1 
ATOM   1534 C C     . ILE A 1 230 ? 107.857 150.018 149.403 1.00 38.06  ? 230 ILE C C     1 
ATOM   1535 O O     . ILE A 1 230 ? 107.644 149.031 150.119 1.00 43.62  ? 230 ILE C O     1 
ATOM   1536 C CB    . ILE A 1 230 ? 109.850 149.113 148.147 1.00 29.95  ? 230 ILE C CB    1 
ATOM   1537 C CG1   . ILE A 1 230 ? 111.314 149.363 147.791 1.00 33.16  ? 230 ILE C CG1   1 
ATOM   1538 C CG2   . ILE A 1 230 ? 109.039 148.859 146.892 1.00 32.72  ? 230 ILE C CG2   1 
ATOM   1539 C CD1   . ILE A 1 230 ? 111.979 148.200 147.106 1.00 31.16  ? 230 ILE C CD1   1 
ATOM   1540 N N     . PRO A 1 231 ? 106.862 150.830 149.052 1.00 37.00  ? 231 PRO C N     1 
ATOM   1541 C CA    . PRO A 1 231 ? 105.512 150.549 149.516 1.00 36.49  ? 231 PRO C CA    1 
ATOM   1542 C C     . PRO A 1 231 ? 105.065 149.182 149.043 1.00 39.12  ? 231 PRO C C     1 
ATOM   1543 O O     . PRO A 1 231 ? 105.525 148.689 147.996 1.00 40.22  ? 231 PRO C O     1 
ATOM   1544 C CB    . PRO A 1 231 ? 104.678 151.668 148.878 1.00 40.74  ? 231 PRO C CB    1 
ATOM   1545 C CG    . PRO A 1 231 ? 105.637 152.754 148.605 1.00 41.07  ? 231 PRO C CG    1 
ATOM   1546 C CD    . PRO A 1 231 ? 106.935 152.090 148.296 1.00 39.89  ? 231 PRO C CD    1 
ATOM   1547 N N     . PRO A 1 232 ? 104.184 148.519 149.790 1.00 35.40  ? 232 PRO C N     1 
ATOM   1548 C CA    . PRO A 1 232 ? 103.706 147.213 149.352 1.00 36.66  ? 232 PRO C CA    1 
ATOM   1549 C C     . PRO A 1 232 ? 103.064 147.315 147.985 1.00 40.70  ? 232 PRO C C     1 
ATOM   1550 O O     . PRO A 1 232 ? 102.504 148.366 147.620 1.00 46.55  ? 232 PRO C O     1 
ATOM   1551 C CB    . PRO A 1 232 ? 102.683 146.831 150.431 1.00 35.17  ? 232 PRO C CB    1 
ATOM   1552 C CG    . PRO A 1 232 ? 103.069 147.602 151.617 1.00 36.57  ? 232 PRO C CG    1 
ATOM   1553 C CD    . PRO A 1 232 ? 103.676 148.874 151.124 1.00 37.36  ? 232 PRO C CD    1 
ATOM   1554 N N     . PRO A 1 233 ? 103.127 146.248 147.184 1.00 33.45  ? 233 PRO C N     1 
ATOM   1555 C CA    . PRO A 1 233 ? 102.589 146.342 145.818 1.00 34.89  ? 233 PRO C CA    1 
ATOM   1556 C C     . PRO A 1 233 ? 101.161 146.850 145.761 1.00 42.24  ? 233 PRO C C     1 
ATOM   1557 O O     . PRO A 1 233 ? 100.834 147.663 144.888 1.00 49.22  ? 233 PRO C O     1 
ATOM   1558 C CB    . PRO A 1 233 ? 102.698 144.901 145.310 1.00 36.71  ? 233 PRO C CB    1 
ATOM   1559 C CG    . PRO A 1 233 ? 103.796 144.304 146.089 1.00 35.59  ? 233 PRO C CG    1 
ATOM   1560 C CD    . PRO A 1 233 ? 103.772 144.949 147.433 1.00 35.89  ? 233 PRO C CD    1 
ATOM   1561 N N     . ARG A 1 234 ? 100.297 146.407 146.676 1.00 43.78  ? 234 ARG C N     1 
ATOM   1562 C CA    . ARG A 1 234 ? 98.927  146.906 146.681 1.00 47.44  ? 234 ARG C CA    1 
ATOM   1563 C C     . ARG A 1 234 ? 98.890  148.411 146.906 1.00 47.59  ? 234 ARG C C     1 
ATOM   1564 O O     . ARG A 1 234 ? 97.983  149.089 146.411 1.00 49.47  ? 234 ARG C O     1 
ATOM   1565 C CB    . ARG A 1 234 ? 98.103  146.183 147.747 1.00 47.51  ? 234 ARG C CB    1 
ATOM   1566 C CG    . ARG A 1 234 ? 98.658  146.297 149.155 1.00 47.29  ? 234 ARG C CG    1 
ATOM   1567 C CD    . ARG A 1 234 ? 97.958  145.338 150.098 1.00 51.30  ? 234 ARG C CD    1 
ATOM   1568 N NE    . ARG A 1 234 ? 98.247  145.622 151.499 1.00 50.68  ? 234 ARG C NE    1 
ATOM   1569 C CZ    . ARG A 1 234 ? 97.574  146.487 152.245 1.00 52.39  ? 234 ARG C CZ    1 
ATOM   1570 N NH1   . ARG A 1 234 ? 96.577  147.202 151.750 1.00 55.02  ? 234 ARG C NH1   1 
ATOM   1571 N NH2   . ARG A 1 234 ? 97.911  146.641 153.522 1.00 51.58  ? 234 ARG C NH2   1 
ATOM   1572 N N     . PHE A 1 235 ? 99.858  148.952 147.645 1.00 47.03  ? 235 PHE C N     1 
ATOM   1573 C CA    . PHE A 1 235 ? 99.985  150.395 147.791 1.00 44.45  ? 235 PHE C CA    1 
ATOM   1574 C C     . PHE A 1 235 ? 100.822 151.016 146.686 1.00 46.95  ? 235 PHE C C     1 
ATOM   1575 O O     . PHE A 1 235 ? 100.671 152.209 146.403 1.00 55.74  ? 235 PHE C O     1 
ATOM   1576 C CB    . PHE A 1 235 ? 100.617 150.751 149.143 1.00 42.61  ? 235 PHE C CB    1 
ATOM   1577 C CG    . PHE A 1 235 ? 99.726  150.497 150.332 1.00 47.61  ? 235 PHE C CG    1 
ATOM   1578 C CD1   . PHE A 1 235 ? 98.348  150.489 150.212 1.00 52.80  ? 235 PHE C CD1   1 
ATOM   1579 C CD2   . PHE A 1 235 ? 100.280 150.297 151.584 1.00 47.39  ? 235 PHE C CD2   1 
ATOM   1580 C CE1   . PHE A 1 235 ? 97.544  150.264 151.310 1.00 54.83  ? 235 PHE C CE1   1 
ATOM   1581 C CE2   . PHE A 1 235 ? 99.479  150.075 152.684 1.00 50.33  ? 235 PHE C CE2   1 
ATOM   1582 C CZ    . PHE A 1 235 ? 98.111  150.058 152.546 1.00 53.34  ? 235 PHE C CZ    1 
ATOM   1583 N N     . LEU A 1 236 ? 101.712 150.242 146.064 1.00 44.27  ? 236 LEU C N     1 
ATOM   1584 C CA    . LEU A 1 236 ? 102.588 150.804 145.042 1.00 46.35  ? 236 LEU C CA    1 
ATOM   1585 C C     . LEU A 1 236 ? 101.838 151.060 143.742 1.00 49.78  ? 236 LEU C C     1 
ATOM   1586 O O     . LEU A 1 236 ? 102.032 152.100 143.103 1.00 50.62  ? 236 LEU C O     1 
ATOM   1587 C CB    . LEU A 1 236 ? 103.774 149.873 144.805 1.00 42.99  ? 236 LEU C CB    1 
ATOM   1588 C CG    . LEU A 1 236 ? 104.796 150.318 143.762 1.00 38.03  ? 236 LEU C CG    1 
ATOM   1589 C CD1   . LEU A 1 236 ? 105.323 151.702 144.071 1.00 40.17  ? 236 LEU C CD1   1 
ATOM   1590 C CD2   . LEU A 1 236 ? 105.930 149.321 143.710 1.00 34.69  ? 236 LEU C CD2   1 
ATOM   1591 N N     . ILE A 1 237 ? 100.976 150.124 143.329 1.00 50.54  ? 237 ILE C N     1 
ATOM   1592 C CA    . ILE A 1 237 ? 100.298 150.256 142.040 1.00 51.21  ? 237 ILE C CA    1 
ATOM   1593 C C     . ILE A 1 237 ? 99.139  151.238 142.067 1.00 54.79  ? 237 ILE C C     1 
ATOM   1594 O O     . ILE A 1 237 ? 98.546  151.502 141.014 1.00 56.02  ? 237 ILE C O     1 
ATOM   1595 C CB    . ILE A 1 237 ? 99.785  148.893 141.540 1.00 48.98  ? 237 ILE C CB    1 
ATOM   1596 C CG1   . ILE A 1 237 ? 98.700  148.347 142.470 1.00 52.93  ? 237 ILE C CG1   1 
ATOM   1597 C CG2   . ILE A 1 237 ? 100.938 147.918 141.420 1.00 42.45  ? 237 ILE C CG2   1 
ATOM   1598 C CD1   . ILE A 1 237 ? 98.243  146.949 142.121 1.00 52.74  ? 237 ILE C CD1   1 
ATOM   1599 N N     . ILE A 1 238 ? 98.794  151.787 143.231 1.00 54.19  ? 238 ILE C N     1 
ATOM   1600 C CA    . ILE A 1 238 ? 97.744  152.791 143.340 1.00 56.83  ? 238 ILE C CA    1 
ATOM   1601 C C     . ILE A 1 238 ? 98.309  154.156 143.708 1.00 57.29  ? 238 ILE C C     1 
ATOM   1602 O O     . ILE A 1 238 ? 97.544  155.102 143.916 1.00 63.22  ? 238 ILE C O     1 
ATOM   1603 C CB    . ILE A 1 238 ? 96.660  152.365 144.346 1.00 58.55  ? 238 ILE C CB    1 
ATOM   1604 C CG1   . ILE A 1 238 ? 97.165  152.514 145.784 1.00 55.93  ? 238 ILE C CG1   1 
ATOM   1605 C CG2   . ILE A 1 238 ? 96.226  150.933 144.082 1.00 56.33  ? 238 ILE C CG2   1 
ATOM   1606 C CD1   . ILE A 1 238 ? 96.196  152.002 146.827 1.00 54.63  ? 238 ILE C CD1   1 
ATOM   1607 N N     . GLY A 1 239 ? 99.630  154.283 143.804 1.00 51.77  ? 239 GLY C N     1 
ATOM   1608 C CA    . GLY A 1 239 ? 100.253 155.541 144.144 1.00 55.35  ? 239 GLY C CA    1 
ATOM   1609 C C     . GLY A 1 239 ? 100.264 155.868 145.620 1.00 59.22  ? 239 GLY C C     1 
ATOM   1610 O O     . GLY A 1 239 ? 100.776 156.930 145.996 1.00 65.92  ? 239 GLY C O     1 
ATOM   1611 N N     . HIS A 1 240 ? 99.723  154.996 146.465 1.00 55.72  ? 240 HIS C N     1 
ATOM   1612 C CA    . HIS A 1 240 ? 99.710  155.245 147.899 1.00 56.72  ? 240 HIS C CA    1 
ATOM   1613 C C     . HIS A 1 240 ? 101.129 155.184 148.450 1.00 57.87  ? 240 HIS C C     1 
ATOM   1614 O O     . HIS A 1 240 ? 101.914 154.305 148.081 1.00 60.00  ? 240 HIS C O     1 
ATOM   1615 C CB    . HIS A 1 240 ? 98.818  154.220 148.594 1.00 53.55  ? 240 HIS C CB    1 
ATOM   1616 C CG    . HIS A 1 240 ? 98.375  154.627 149.963 1.00 54.69  ? 240 HIS C CG    1 
ATOM   1617 N ND1   . HIS A 1 240 ? 99.080  155.520 150.740 1.00 61.16  ? 240 HIS C ND1   1 
ATOM   1618 C CD2   . HIS A 1 240 ? 97.285  154.279 150.687 1.00 56.30  ? 240 HIS C CD2   1 
ATOM   1619 C CE1   . HIS A 1 240 ? 98.453  155.692 151.889 1.00 64.10  ? 240 HIS C CE1   1 
ATOM   1620 N NE2   . HIS A 1 240 ? 97.360  154.951 151.882 1.00 61.29  ? 240 HIS C NE2   1 
ATOM   1621 N N     . ARG A 1 241 ? 101.460 156.125 149.328 1.00 59.00  ? 241 ARG C N     1 
ATOM   1622 C CA    . ARG A 1 241 ? 102.771 156.191 149.958 1.00 60.10  ? 241 ARG C CA    1 
ATOM   1623 C C     . ARG A 1 241 ? 102.670 155.665 151.383 1.00 62.93  ? 241 ARG C C     1 
ATOM   1624 O O     . ARG A 1 241 ? 101.808 156.103 152.151 1.00 61.04  ? 241 ARG C O     1 
ATOM   1625 C CB    . ARG A 1 241 ? 103.302 157.624 149.963 1.00 65.12  ? 241 ARG C CB    1 
ATOM   1626 C CG    . ARG A 1 241 ? 104.816 157.720 150.058 1.00 69.00  ? 241 ARG C CG    1 
ATOM   1627 C CD    . ARG A 1 241 ? 105.274 159.144 150.338 1.00 70.29  ? 241 ARG C CD    1 
ATOM   1628 N NE    . ARG A 1 241 ? 105.491 159.898 149.107 1.00 74.69  ? 241 ARG C NE    1 
ATOM   1629 C CZ    . ARG A 1 241 ? 106.642 160.446 148.735 1.00 79.32  ? 241 ARG C CZ    1 
ATOM   1630 N NH1   . ARG A 1 241 ? 107.733 160.351 149.479 1.00 85.87  ? 241 ARG C NH1   1 
ATOM   1631 N NH2   . ARG A 1 241 ? 106.699 161.110 147.584 1.00 79.51  ? 241 ARG C NH2   1 
ATOM   1632 N N     . LEU A 1 242 ? 103.547 154.727 151.729 1.00 60.05  ? 242 LEU C N     1 
ATOM   1633 C CA    . LEU A 1 242 ? 103.543 154.168 153.073 1.00 53.84  ? 242 LEU C CA    1 
ATOM   1634 C C     . LEU A 1 242 ? 103.808 155.264 154.096 1.00 57.19  ? 242 LEU C C     1 
ATOM   1635 O O     . LEU A 1 242 ? 104.733 156.065 153.940 1.00 58.62  ? 242 LEU C O     1 
ATOM   1636 C CB    . LEU A 1 242 ? 104.598 153.069 153.187 1.00 49.31  ? 242 LEU C CB    1 
ATOM   1637 C CG    . LEU A 1 242 ? 104.460 152.117 154.376 1.00 51.09  ? 242 LEU C CG    1 
ATOM   1638 C CD1   . LEU A 1 242 ? 103.212 151.261 154.247 1.00 53.70  ? 242 LEU C CD1   1 
ATOM   1639 C CD2   . LEU A 1 242 ? 105.693 151.247 154.495 1.00 47.26  ? 242 LEU C CD2   1 
ATOM   1640 N N     . GLN A 1 243 ? 102.994 155.296 155.145 1.00 61.94  ? 243 GLN C N     1 
ATOM   1641 C CA    . GLN A 1 243 ? 103.099 156.319 156.178 1.00 65.67  ? 243 GLN C CA    1 
ATOM   1642 C C     . GLN A 1 243 ? 102.508 155.757 157.467 1.00 64.06  ? 243 GLN C C     1 
ATOM   1643 O O     . GLN A 1 243 ? 102.280 154.549 157.589 1.00 65.78  ? 243 GLN C O     1 
ATOM   1644 C CB    . GLN A 1 243 ? 102.407 157.614 155.736 1.00 71.07  ? 243 GLN C CB    1 
ATOM   1645 C CG    . GLN A 1 243 ? 100.936 157.449 155.386 1.00 73.25  ? 243 GLN C CG    1 
ATOM   1646 C CD    . GLN A 1 243 ? 100.404 158.594 154.546 1.00 70.92  ? 243 GLN C CD    1 
ATOM   1647 O OE1   . GLN A 1 243 ? 101.169 159.390 154.003 1.00 71.20  ? 243 GLN C OE1   1 
ATOM   1648 N NE2   . GLN A 1 243 ? 99.084  158.678 154.431 1.00 66.28  ? 243 GLN C NE2   1 
ATOM   1649 N N     . ILE A 1 244 ? 102.270 156.633 158.436 1.00 62.10  ? 244 ILE C N     1 
ATOM   1650 C CA    . ILE A 1 244 ? 101.749 156.223 159.734 1.00 64.56  ? 244 ILE C CA    1 
ATOM   1651 C C     . ILE A 1 244 ? 100.229 156.262 159.697 1.00 65.47  ? 244 ILE C C     1 
ATOM   1652 O O     . ILE A 1 244 ? 99.631  157.234 159.222 1.00 68.64  ? 244 ILE C O     1 
ATOM   1653 C CB    . ILE A 1 244 ? 102.296 157.126 160.849 1.00 65.65  ? 244 ILE C CB    1 
ATOM   1654 C CG1   . ILE A 1 244 ? 103.818 157.008 160.932 1.00 65.49  ? 244 ILE C CG1   1 
ATOM   1655 C CG2   . ILE A 1 244 ? 101.669 156.760 162.180 1.00 63.88  ? 244 ILE C CG2   1 
ATOM   1656 C CD1   . ILE A 1 244 ? 104.478 158.169 161.633 1.00 64.21  ? 244 ILE C CD1   1 
ATOM   1657 N N     . GLY A 1 245 ? 99.600  155.208 160.203 1.00 69.27  ? 245 GLY C N     1 
ATOM   1658 C CA    . GLY A 1 245 ? 98.158  155.143 160.290 1.00 72.79  ? 245 GLY C CA    1 
ATOM   1659 C C     . GLY A 1 245 ? 97.471  154.342 159.207 1.00 78.41  ? 245 GLY C C     1 
ATOM   1660 O O     . GLY A 1 245 ? 96.239  154.392 159.118 1.00 81.58  ? 245 GLY C O     1 
ATOM   1661 N N     . ASP A 1 246 ? 98.218  153.610 158.387 1.00 75.59  ? 246 ASP C N     1 
ATOM   1662 C CA    . ASP A 1 246 ? 97.656  152.783 157.327 1.00 75.10  ? 246 ASP C CA    1 
ATOM   1663 C C     . ASP A 1 246 ? 97.849  151.316 157.684 1.00 69.22  ? 246 ASP C C     1 
ATOM   1664 O O     . ASP A 1 246 ? 98.953  150.899 158.048 1.00 65.44  ? 246 ASP C O     1 
ATOM   1665 C CB    . ASP A 1 246 ? 98.307  153.102 155.979 1.00 74.08  ? 246 ASP C CB    1 
ATOM   1666 C CG    . ASP A 1 246 ? 99.792  153.347 156.097 1.00 69.21  ? 246 ASP C CG    1 
ATOM   1667 O OD1   . ASP A 1 246 ? 100.336 153.114 157.193 1.00 67.15  ? 246 ASP C OD1   1 
ATOM   1668 O OD2   . ASP A 1 246 ? 100.411 153.787 155.105 1.00 67.93  ? 246 ASP C OD2   1 
ATOM   1669 N N     . GLN A 1 247 ? 96.774  150.540 157.577 1.00 66.66  ? 247 GLN C N     1 
ATOM   1670 C CA    . GLN A 1 247 ? 96.792  149.155 158.022 1.00 66.62  ? 247 GLN C CA    1 
ATOM   1671 C C     . GLN A 1 247 ? 97.677  148.308 157.117 1.00 58.89  ? 247 GLN C C     1 
ATOM   1672 O O     . GLN A 1 247 ? 97.550  148.350 155.890 1.00 65.72  ? 247 GLN C O     1 
ATOM   1673 C CB    . GLN A 1 247 ? 95.371  148.599 158.039 1.00 71.93  ? 247 GLN C CB    1 
ATOM   1674 C CG    . GLN A 1 247 ? 94.427  149.352 158.965 1.00 73.89  ? 247 GLN C CG    1 
ATOM   1675 C CD    . GLN A 1 247 ? 92.971  149.135 158.614 1.00 74.64  ? 247 GLN C CD    1 
ATOM   1676 O OE1   . GLN A 1 247 ? 92.623  148.949 157.448 1.00 73.77  ? 247 GLN C OE1   1 
ATOM   1677 N NE2   . GLN A 1 247 ? 92.109  149.155 159.623 1.00 76.40  ? 247 GLN C NE2   1 
ATOM   1678 N N     . VAL A 1 248 ? 98.573  147.531 157.725 1.00 52.22  ? 248 VAL C N     1 
ATOM   1679 C CA    . VAL A 1 248 ? 99.461  146.622 157.010 1.00 51.27  ? 248 VAL C CA    1 
ATOM   1680 C C     . VAL A 1 248 ? 99.747  145.429 157.912 1.00 53.11  ? 248 VAL C C     1 
ATOM   1681 O O     . VAL A 1 248 ? 99.430  145.432 159.102 1.00 64.02  ? 248 VAL C O     1 
ATOM   1682 C CB    . VAL A 1 248 ? 100.784 147.300 156.587 1.00 54.36  ? 248 VAL C CB    1 
ATOM   1683 C CG1   . VAL A 1 248 ? 100.514 148.581 155.817 1.00 54.68  ? 248 VAL C CG1   1 
ATOM   1684 C CG2   . VAL A 1 248 ? 101.656 147.574 157.798 1.00 57.65  ? 248 VAL C CG2   1 
ATOM   1685 N N     . THR A 1 249 ? 100.355 144.399 157.338 1.00 49.66  ? 249 THR C N     1 
ATOM   1686 C CA    . THR A 1 249 ? 100.769 143.223 158.085 1.00 51.11  ? 249 THR C CA    1 
ATOM   1687 C C     . THR A 1 249 ? 102.224 143.365 158.519 1.00 47.15  ? 249 THR C C     1 
ATOM   1688 O O     . THR A 1 249 ? 102.997 144.131 157.942 1.00 42.81  ? 249 THR C O     1 
ATOM   1689 C CB    . THR A 1 249 ? 100.591 141.960 157.242 1.00 50.97  ? 249 THR C CB    1 
ATOM   1690 O OG1   . THR A 1 249 ? 99.236  141.878 156.786 1.00 57.07  ? 249 THR C OG1   1 
ATOM   1691 C CG2   . THR A 1 249 ? 100.925 140.719 158.049 1.00 51.64  ? 249 THR C CG2   1 
ATOM   1692 N N     . LEU A 1 250 ? 102.591 142.616 159.561 1.00 51.63  ? 250 LEU C N     1 
ATOM   1693 C CA    . LEU A 1 250 ? 103.947 142.712 160.089 1.00 50.57  ? 250 LEU C CA    1 
ATOM   1694 C C     . LEU A 1 250 ? 104.974 142.322 159.034 1.00 43.83  ? 250 LEU C C     1 
ATOM   1695 O O     . LEU A 1 250 ? 105.975 143.020 158.840 1.00 46.64  ? 250 LEU C O     1 
ATOM   1696 C CB    . LEU A 1 250 ? 104.096 141.831 161.327 1.00 49.31  ? 250 LEU C CB    1 
ATOM   1697 C CG    . LEU A 1 250 ? 105.511 141.755 161.904 1.00 43.11  ? 250 LEU C CG    1 
ATOM   1698 C CD1   . LEU A 1 250 ? 106.085 143.145 162.119 1.00 41.68  ? 250 LEU C CD1   1 
ATOM   1699 C CD2   . LEU A 1 250 ? 105.517 140.967 163.200 1.00 46.14  ? 250 LEU C CD2   1 
ATOM   1700 N N     . ARG A 1 251 ? 104.743 141.207 158.341 1.00 37.00  ? 251 ARG C N     1 
ATOM   1701 C CA    . ARG A 1 251 ? 105.661 140.810 157.281 1.00 37.77  ? 251 ARG C CA    1 
ATOM   1702 C C     . ARG A 1 251 ? 105.670 141.838 156.159 1.00 39.65  ? 251 ARG C C     1 
ATOM   1703 O O     . ARG A 1 251 ? 106.726 142.143 155.594 1.00 40.26  ? 251 ARG C O     1 
ATOM   1704 C CB    . ARG A 1 251 ? 105.285 139.429 156.750 1.00 42.61  ? 251 ARG C CB    1 
ATOM   1705 C CG    . ARG A 1 251 ? 105.791 138.291 157.615 1.00 45.24  ? 251 ARG C CG    1 
ATOM   1706 C CD    . ARG A 1 251 ? 105.620 136.943 156.937 1.00 50.73  ? 251 ARG C CD    1 
ATOM   1707 N NE    . ARG A 1 251 ? 106.625 136.713 155.906 1.00 48.46  ? 251 ARG C NE    1 
ATOM   1708 C CZ    . ARG A 1 251 ? 106.656 135.651 155.114 1.00 48.56  ? 251 ARG C CZ    1 
ATOM   1709 N NH1   . ARG A 1 251 ? 105.755 134.687 155.212 1.00 48.68  ? 251 ARG C NH1   1 
ATOM   1710 N NH2   . ARG A 1 251 ? 107.618 135.551 154.202 1.00 47.94  ? 251 ARG C NH2   1 
ATOM   1711 N N     . GLU A 1 252 ? 104.503 142.393 155.829 1.00 42.63  ? 252 GLU C N     1 
ATOM   1712 C CA    . GLU A 1 252 ? 104.441 143.435 154.811 1.00 37.82  ? 252 GLU C CA    1 
ATOM   1713 C C     . GLU A 1 252 ? 105.334 144.610 155.182 1.00 40.28  ? 252 GLU C C     1 
ATOM   1714 O O     . GLU A 1 252 ? 106.169 145.045 154.383 1.00 43.46  ? 252 GLU C O     1 
ATOM   1715 C CB    . GLU A 1 252 ? 102.999 143.904 154.631 1.00 41.64  ? 252 GLU C CB    1 
ATOM   1716 C CG    . GLU A 1 252 ? 102.157 143.019 153.740 1.00 48.66  ? 252 GLU C CG    1 
ATOM   1717 C CD    . GLU A 1 252 ? 100.731 143.513 153.626 1.00 56.42  ? 252 GLU C CD    1 
ATOM   1718 O OE1   . GLU A 1 252 ? 100.525 144.744 153.655 1.00 61.02  ? 252 GLU C OE1   1 
ATOM   1719 O OE2   . GLU A 1 252 ? 99.813  142.674 153.516 1.00 51.94  ? 252 GLU C OE2   1 
ATOM   1720 N N     . LEU A 1 253 ? 105.177 145.136 156.398 1.00 38.70  ? 253 LEU C N     1 
ATOM   1721 C CA    . LEU A 1 253 ? 105.967 146.293 156.804 1.00 36.99  ? 253 LEU C CA    1 
ATOM   1722 C C     . LEU A 1 253 ? 107.450 145.957 156.862 1.00 35.61  ? 253 LEU C C     1 
ATOM   1723 O O     . LEU A 1 253 ? 108.291 146.750 156.421 1.00 37.36  ? 253 LEU C O     1 
ATOM   1724 C CB    . LEU A 1 253 ? 105.489 146.808 158.159 1.00 36.36  ? 253 LEU C CB    1 
ATOM   1725 C CG    . LEU A 1 253 ? 106.192 148.077 158.642 1.00 36.13  ? 253 LEU C CG    1 
ATOM   1726 C CD1   . LEU A 1 253 ? 105.750 149.273 157.824 1.00 38.40  ? 253 LEU C CD1   1 
ATOM   1727 C CD2   . LEU A 1 253 ? 105.943 148.315 160.114 1.00 43.57  ? 253 LEU C CD2   1 
ATOM   1728 N N     . LEU A 1 254 ? 107.794 144.792 157.411 1.00 32.74  ? 254 LEU C N     1 
ATOM   1729 C CA    . LEU A 1 254 ? 109.201 144.438 157.541 1.00 28.68  ? 254 LEU C CA    1 
ATOM   1730 C C     . LEU A 1 254 ? 109.855 144.286 156.176 1.00 27.38  ? 254 LEU C C     1 
ATOM   1731 O O     . LEU A 1 254 ? 111.013 144.673 155.990 1.00 34.45  ? 254 LEU C O     1 
ATOM   1732 C CB    . LEU A 1 254 ? 109.347 143.157 158.357 1.00 33.00  ? 254 LEU C CB    1 
ATOM   1733 C CG    . LEU A 1 254 ? 109.034 143.297 159.847 1.00 36.14  ? 254 LEU C CG    1 
ATOM   1734 C CD1   . LEU A 1 254 ? 109.082 141.938 160.522 1.00 41.44  ? 254 LEU C CD1   1 
ATOM   1735 C CD2   . LEU A 1 254 ? 109.991 144.263 160.520 1.00 35.46  ? 254 LEU C CD2   1 
ATOM   1736 N N     . ALA A 1 255 ? 109.136 143.720 155.207 1.00 26.13  ? 255 ALA C N     1 
ATOM   1737 C CA    . ALA A 1 255 ? 109.670 143.661 153.853 1.00 30.34  ? 255 ALA C CA    1 
ATOM   1738 C C     . ALA A 1 255 ? 109.750 145.046 153.232 1.00 30.99  ? 255 ALA C C     1 
ATOM   1739 O O     . ALA A 1 255 ? 110.661 145.320 152.444 1.00 31.90  ? 255 ALA C O     1 
ATOM   1740 C CB    . ALA A 1 255 ? 108.810 142.746 152.988 1.00 34.17  ? 255 ALA C CB    1 
ATOM   1741 N N     . SER A 1 256 ? 108.804 145.923 153.564 1.00 30.33  ? 256 SER C N     1 
ATOM   1742 C CA    . SER A 1 256 ? 108.816 147.268 153.005 1.00 30.19  ? 256 SER C CA    1 
ATOM   1743 C C     . SER A 1 256 ? 110.033 148.058 153.467 1.00 31.97  ? 256 SER C C     1 
ATOM   1744 O O     . SER A 1 256 ? 110.670 148.745 152.662 1.00 34.70  ? 256 SER C O     1 
ATOM   1745 C CB    . SER A 1 256 ? 107.535 147.999 153.391 1.00 30.25  ? 256 SER C CB    1 
ATOM   1746 O OG    . SER A 1 256 ? 107.740 149.397 153.395 1.00 32.04  ? 256 SER C OG    1 
ATOM   1747 N N     . ILE A 1 257 ? 110.380 147.971 154.755 1.00 30.84  ? 257 ILE C N     1 
ATOM   1748 C CA    . ILE A 1 257 ? 111.425 148.829 155.315 1.00 27.60  ? 257 ILE C CA    1 
ATOM   1749 C C     . ILE A 1 257 ? 112.750 148.112 155.542 1.00 29.85  ? 257 ILE C C     1 
ATOM   1750 O O     . ILE A 1 257 ? 113.757 148.783 155.816 1.00 38.05  ? 257 ILE C O     1 
ATOM   1751 C CB    . ILE A 1 257 ? 110.969 149.473 156.641 1.00 27.51  ? 257 ILE C CB    1 
ATOM   1752 C CG1   . ILE A 1 257 ? 110.896 148.423 157.747 1.00 31.07  ? 257 ILE C CG1   1 
ATOM   1753 C CG2   . ILE A 1 257 ? 109.629 150.154 156.461 1.00 32.89  ? 257 ILE C CG2   1 
ATOM   1754 C CD1   . ILE A 1 257 ? 110.114 148.867 158.960 1.00 35.13  ? 257 ILE C CD1   1 
ATOM   1755 N N     . ALA A 1 258 ? 112.793 146.789 155.440 1.00 27.03  ? 258 ALA C N     1 
ATOM   1756 C CA    . ALA A 1 258 ? 114.016 146.045 155.717 1.00 24.98  ? 258 ALA C CA    1 
ATOM   1757 C C     . ALA A 1 258 ? 113.892 144.669 155.076 1.00 27.46  ? 258 ALA C C     1 
ATOM   1758 O O     . ALA A 1 258 ? 112.975 144.417 154.289 1.00 37.37  ? 258 ALA C O     1 
ATOM   1759 C CB    . ALA A 1 258 ? 114.266 145.956 157.224 1.00 29.37  ? 258 ALA C CB    1 
ATOM   1760 N N     . TRP A 1 259 ? 114.818 143.772 155.408 1.00 27.89  ? 259 TRP C N     1 
ATOM   1761 C CA    . TRP A 1 259 ? 114.783 142.410 154.892 1.00 33.81  ? 259 TRP C CA    1 
ATOM   1762 C C     . TRP A 1 259 ? 115.135 141.453 156.025 1.00 37.36  ? 259 TRP C C     1 
ATOM   1763 O O     . TRP A 1 259 ? 115.141 141.825 157.201 1.00 37.59  ? 259 TRP C O     1 
ATOM   1764 C CB    . TRP A 1 259 ? 115.704 142.257 153.674 1.00 36.67  ? 259 TRP C CB    1 
ATOM   1765 C CG    . TRP A 1 259 ? 117.146 142.564 153.907 1.00 32.11  ? 259 TRP C CG    1 
ATOM   1766 C CD1   . TRP A 1 259 ? 117.688 143.776 154.208 1.00 33.83  ? 259 TRP C CD1   1 
ATOM   1767 C CD2   . TRP A 1 259 ? 118.239 141.644 153.825 1.00 35.81  ? 259 TRP C CD2   1 
ATOM   1768 N NE1   . TRP A 1 259 ? 119.051 143.667 154.329 1.00 38.05  ? 259 TRP C NE1   1 
ATOM   1769 C CE2   . TRP A 1 259 ? 119.413 142.367 154.098 1.00 40.29  ? 259 TRP C CE2   1 
ATOM   1770 C CE3   . TRP A 1 259 ? 118.338 140.278 153.553 1.00 38.91  ? 259 TRP C CE3   1 
ATOM   1771 C CZ2   . TRP A 1 259 ? 120.670 141.770 154.110 1.00 47.07  ? 259 TRP C CZ2   1 
ATOM   1772 C CZ3   . TRP A 1 259 ? 119.586 139.688 153.565 1.00 39.05  ? 259 TRP C CZ3   1 
ATOM   1773 C CH2   . TRP A 1 259 ? 120.734 140.432 153.840 1.00 43.54  ? 259 TRP C CH2   1 
ATOM   1774 N N     . GLY A 1 260 ? 115.419 140.202 155.663 1.00 40.37  ? 260 GLY C N     1 
ATOM   1775 C CA    . GLY A 1 260 ? 115.470 139.143 156.659 1.00 43.53  ? 260 GLY C CA    1 
ATOM   1776 C C     . GLY A 1 260 ? 116.562 139.332 157.694 1.00 47.71  ? 260 GLY C C     1 
ATOM   1777 O O     . GLY A 1 260 ? 116.338 139.119 158.887 1.00 47.41  ? 260 GLY C O     1 
ATOM   1778 N N     . LEU A 1 261 ? 117.754 139.722 157.258 1.00 50.41  ? 261 LEU C N     1 
ATOM   1779 C CA    . LEU A 1 261 ? 118.921 139.741 158.129 1.00 42.65  ? 261 LEU C CA    1 
ATOM   1780 C C     . LEU A 1 261 ? 119.152 141.087 158.802 1.00 39.66  ? 261 LEU C C     1 
ATOM   1781 O O     . LEU A 1 261 ? 120.149 141.239 159.511 1.00 46.14  ? 261 LEU C O     1 
ATOM   1782 C CB    . LEU A 1 261 ? 120.170 139.344 157.339 1.00 48.81  ? 261 LEU C CB    1 
ATOM   1783 C CG    . LEU A 1 261 ? 120.458 137.843 157.283 1.00 55.21  ? 261 LEU C CG    1 
ATOM   1784 C CD1   . LEU A 1 261 ? 121.005 137.348 158.604 1.00 54.31  ? 261 LEU C CD1   1 
ATOM   1785 C CD2   . LEU A 1 261 ? 119.210 137.074 156.909 1.00 54.60  ? 261 LEU C CD2   1 
ATOM   1786 N N     . CYS A 1 262 ? 118.275 142.063 158.602 1.00 36.54  ? 262 CYS C N     1 
ATOM   1787 C CA    . CYS A 1 262 ? 118.377 143.298 159.359 1.00 40.06  ? 262 CYS C CA    1 
ATOM   1788 C C     . CYS A 1 262 ? 117.992 143.046 160.814 1.00 43.44  ? 262 CYS C C     1 
ATOM   1789 O O     . CYS A 1 262 ? 117.374 142.034 161.152 1.00 54.66  ? 262 CYS C O     1 
ATOM   1790 C CB    . CYS A 1 262 ? 117.481 144.378 158.754 1.00 41.91  ? 262 CYS C CB    1 
ATOM   1791 S SG    . CYS A 1 262 ? 118.325 145.471 157.590 1.00 58.11  ? 262 CYS C SG    1 
ATOM   1792 N N     . ASP A 1 263 ? 118.368 143.979 161.684 1.00 40.28  ? 263 ASP C N     1 
ATOM   1793 C CA    . ASP A 1 263 ? 118.092 143.802 163.100 1.00 44.25  ? 263 ASP C CA    1 
ATOM   1794 C C     . ASP A 1 263 ? 116.589 143.734 163.346 1.00 44.71  ? 263 ASP C C     1 
ATOM   1795 O O     . ASP A 1 263 ? 115.778 144.234 162.565 1.00 48.68  ? 263 ASP C O     1 
ATOM   1796 C CB    . ASP A 1 263 ? 118.702 144.937 163.919 1.00 48.36  ? 263 ASP C CB    1 
ATOM   1797 C CG    . ASP A 1 263 ? 118.535 144.730 165.412 1.00 54.42  ? 263 ASP C CG    1 
ATOM   1798 O OD1   . ASP A 1 263 ? 117.381 144.586 165.867 1.00 51.22  ? 263 ASP C OD1   1 
ATOM   1799 O OD2   . ASP A 1 263 ? 119.555 144.706 166.131 1.00 60.15  ? 263 ASP C OD2   1 
ATOM   1800 N N     . GLY A 1 264 ? 116.221 143.091 164.452 1.00 46.15  ? 264 GLY C N     1 
ATOM   1801 C CA    . GLY A 1 264 ? 114.824 142.905 164.792 1.00 47.93  ? 264 GLY C CA    1 
ATOM   1802 C C     . GLY A 1 264 ? 114.141 144.111 165.386 1.00 48.52  ? 264 GLY C C     1 
ATOM   1803 O O     . GLY A 1 264 ? 112.908 144.136 165.453 1.00 48.94  ? 264 GLY C O     1 
ATOM   1804 N N     . VAL A 1 265 ? 114.906 145.121 165.804 1.00 48.54  ? 265 VAL C N     1 
ATOM   1805 C CA    . VAL A 1 265 ? 114.305 146.283 166.450 1.00 49.55  ? 265 VAL C CA    1 
ATOM   1806 C C     . VAL A 1 265 ? 113.294 146.948 165.531 1.00 50.69  ? 265 VAL C C     1 
ATOM   1807 O O     . VAL A 1 265 ? 112.337 147.575 165.999 1.00 53.35  ? 265 VAL C O     1 
ATOM   1808 C CB    . VAL A 1 265 ? 115.397 147.277 166.887 1.00 52.00  ? 265 VAL C CB    1 
ATOM   1809 C CG1   . VAL A 1 265 ? 116.175 147.788 165.685 1.00 51.30  ? 265 VAL C CG1   1 
ATOM   1810 C CG2   . VAL A 1 265 ? 114.779 148.432 167.651 1.00 56.79  ? 265 VAL C CG2   1 
ATOM   1811 N N     . LEU A 1 266 ? 113.477 146.820 164.216 1.00 48.09  ? 266 LEU C N     1 
ATOM   1812 C CA    . LEU A 1 266 ? 112.560 147.454 163.279 1.00 46.60  ? 266 LEU C CA    1 
ATOM   1813 C C     . LEU A 1 266 ? 111.133 146.962 163.459 1.00 47.55  ? 266 LEU C C     1 
ATOM   1814 O O     . LEU A 1 266 ? 110.194 147.666 163.075 1.00 50.27  ? 266 LEU C O     1 
ATOM   1815 C CB    . LEU A 1 266 ? 113.027 147.205 161.846 1.00 38.66  ? 266 LEU C CB    1 
ATOM   1816 C CG    . LEU A 1 266 ? 114.400 147.787 161.519 1.00 37.59  ? 266 LEU C CG    1 
ATOM   1817 C CD1   . LEU A 1 266 ? 115.103 146.926 160.498 1.00 37.12  ? 266 LEU C CD1   1 
ATOM   1818 C CD2   . LEU A 1 266 ? 114.271 149.210 161.023 1.00 42.72  ? 266 LEU C CD2   1 
ATOM   1819 N N     . ALA A 1 267 ? 110.945 145.785 164.057 1.00 46.07  ? 267 ALA C N     1 
ATOM   1820 C CA    . ALA A 1 267 ? 109.596 145.292 164.293 1.00 44.20  ? 267 ALA C CA    1 
ATOM   1821 C C     . ALA A 1 267 ? 108.803 146.223 165.195 1.00 52.30  ? 267 ALA C C     1 
ATOM   1822 O O     . ALA A 1 267 ? 107.571 146.132 165.233 1.00 57.54  ? 267 ALA C O     1 
ATOM   1823 C CB    . ALA A 1 267 ? 109.647 143.894 164.905 1.00 51.78  ? 267 ALA C CB    1 
ATOM   1824 N N     . GLU A 1 268 ? 109.478 147.109 165.929 1.00 55.87  ? 268 GLU C N     1 
ATOM   1825 C CA    . GLU A 1 268 ? 108.791 148.094 166.754 1.00 61.70  ? 268 GLU C CA    1 
ATOM   1826 C C     . GLU A 1 268 ? 108.029 149.127 165.935 1.00 62.17  ? 268 GLU C C     1 
ATOM   1827 O O     . GLU A 1 268 ? 107.218 149.864 166.505 1.00 61.64  ? 268 GLU C O     1 
ATOM   1828 C CB    . GLU A 1 268 ? 109.796 148.801 167.664 1.00 60.69  ? 268 GLU C CB    1 
ATOM   1829 C CG    . GLU A 1 268 ? 110.103 148.044 168.941 1.00 63.05  ? 268 GLU C CG    1 
ATOM   1830 C CD    . GLU A 1 268 ? 108.954 148.093 169.930 1.00 70.98  ? 268 GLU C CD    1 
ATOM   1831 O OE1   . GLU A 1 268 ? 108.784 149.136 170.596 1.00 81.56  ? 268 GLU C OE1   1 
ATOM   1832 O OE2   . GLU A 1 268 ? 108.218 147.090 170.039 1.00 67.87  ? 268 GLU C OE2   1 
ATOM   1833 N N     . CYS A 1 269 ? 108.267 149.205 164.625 1.00 59.42  ? 269 CYS C N     1 
ATOM   1834 C CA    . CYS A 1 269 ? 107.531 150.144 163.790 1.00 55.24  ? 269 CYS C CA    1 
ATOM   1835 C C     . CYS A 1 269 ? 106.086 149.726 163.564 1.00 54.93  ? 269 CYS C C     1 
ATOM   1836 O O     . CYS A 1 269 ? 105.311 150.522 163.027 1.00 64.86  ? 269 CYS C O     1 
ATOM   1837 C CB    . CYS A 1 269 ? 108.232 150.305 162.441 1.00 50.24  ? 269 CYS C CB    1 
ATOM   1838 S SG    . CYS A 1 269 ? 109.842 151.111 162.538 1.00 57.33  ? 269 CYS C SG    1 
ATOM   1839 N N     . TRP A 1 270 ? 105.706 148.514 163.956 1.00 55.38  ? 270 TRP C N     1 
ATOM   1840 C CA    . TRP A 1 270 ? 104.365 147.996 163.741 1.00 59.12  ? 270 TRP C CA    1 
ATOM   1841 C C     . TRP A 1 270 ? 103.690 147.739 165.081 1.00 62.08  ? 270 TRP C C     1 
ATOM   1842 O O     . TRP A 1 270 ? 104.350 147.409 166.070 1.00 63.19  ? 270 TRP C O     1 
ATOM   1843 C CB    . TRP A 1 270 ? 104.405 146.702 162.922 1.00 57.50  ? 270 TRP C CB    1 
ATOM   1844 C CG    . TRP A 1 270 ? 103.069 146.090 162.688 1.00 58.62  ? 270 TRP C CG    1 
ATOM   1845 C CD1   . TRP A 1 270 ? 102.070 146.583 161.906 1.00 55.67  ? 270 TRP C CD1   1 
ATOM   1846 C CD2   . TRP A 1 270 ? 102.580 144.862 163.237 1.00 59.70  ? 270 TRP C CD2   1 
ATOM   1847 N NE1   . TRP A 1 270 ? 100.987 145.740 161.934 1.00 57.35  ? 270 TRP C NE1   1 
ATOM   1848 C CE2   . TRP A 1 270 ? 101.276 144.675 162.746 1.00 59.90  ? 270 TRP C CE2   1 
ATOM   1849 C CE3   . TRP A 1 270 ? 103.119 143.904 164.100 1.00 58.93  ? 270 TRP C CE3   1 
ATOM   1850 C CZ2   . TRP A 1 270 ? 100.503 143.569 163.087 1.00 62.24  ? 270 TRP C CZ2   1 
ATOM   1851 C CZ3   . TRP A 1 270 ? 102.350 142.808 164.437 1.00 58.91  ? 270 TRP C CZ3   1 
ATOM   1852 C CH2   . TRP A 1 270 ? 101.057 142.649 163.932 1.00 60.59  ? 270 TRP C CH2   1 
ATOM   1853 N N     . SER A 1 271 ? 102.366 147.896 165.110 1.00 64.52  ? 271 SER C N     1 
ATOM   1854 C CA    . SER A 1 271 ? 101.597 147.626 166.317 1.00 63.66  ? 271 SER C CA    1 
ATOM   1855 C C     . SER A 1 271 ? 100.339 146.846 165.951 1.00 67.51  ? 271 SER C C     1 
ATOM   1856 O O     . SER A 1 271 ? 99.545  147.317 165.127 1.00 71.68  ? 271 SER C O     1 
ATOM   1857 C CB    . SER A 1 271 ? 101.230 148.928 167.027 1.00 64.78  ? 271 SER C CB    1 
ATOM   1858 O OG    . SER A 1 271 ? 100.204 149.615 166.333 1.00 65.48  ? 271 SER C OG    1 
ATOM   1859 N N     . PRO A 1 272 ? 100.118 145.661 166.521 1.00 70.40  ? 272 PRO C N     1 
ATOM   1860 C CA    . PRO A 1 272 ? 98.928  144.889 166.153 1.00 72.00  ? 272 PRO C CA    1 
ATOM   1861 C C     . PRO A 1 272 ? 97.653  145.604 166.566 1.00 75.85  ? 272 PRO C C     1 
ATOM   1862 O O     . PRO A 1 272 ? 97.624  146.362 167.537 1.00 73.04  ? 272 PRO C O     1 
ATOM   1863 C CB    . PRO A 1 272 ? 99.104  143.571 166.914 1.00 72.33  ? 272 PRO C CB    1 
ATOM   1864 C CG    . PRO A 1 272 ? 100.013 143.894 168.035 1.00 72.46  ? 272 PRO C CG    1 
ATOM   1865 C CD    . PRO A 1 272 ? 100.928 144.968 167.537 1.00 72.64  ? 272 PRO C CD    1 
ATOM   1866 N N     . SER A 1 273 ? 96.590  145.357 165.806 1.00 85.99  ? 273 SER C N     1 
ATOM   1867 C CA    . SER A 1 273 ? 95.298  145.961 166.075 1.00 92.91  ? 273 SER C CA    1 
ATOM   1868 C C     . SER A 1 273 ? 94.525  145.112 167.080 1.00 99.13  ? 273 SER C C     1 
ATOM   1869 O O     . SER A 1 273 ? 94.963  144.038 167.498 1.00 95.45  ? 273 SER C O     1 
ATOM   1870 C CB    . SER A 1 273 ? 94.508  146.130 164.778 1.00 93.49  ? 273 SER C CB    1 
ATOM   1871 O OG    . SER A 1 273 ? 93.612  145.050 164.586 1.00 96.66  ? 273 SER C OG    1 
ATOM   1872 N N     . GLN A 1 274 ? 93.354  145.605 167.472 1.00 106.22 ? 274 GLN C N     1 
ATOM   1873 C CA    . GLN A 1 274 ? 92.508  144.885 168.412 1.00 110.09 ? 274 GLN C CA    1 
ATOM   1874 C C     . GLN A 1 274 ? 92.173  143.506 167.861 1.00 111.76 ? 274 GLN C C     1 
ATOM   1875 O O     . GLN A 1 274 ? 91.681  143.380 166.735 1.00 111.59 ? 274 GLN C O     1 
ATOM   1876 C CB    . GLN A 1 274 ? 91.232  145.683 168.668 1.00 111.53 ? 274 GLN C CB    1 
ATOM   1877 C CG    . GLN A 1 274 ? 91.461  147.034 169.329 1.00 110.42 ? 274 GLN C CG    1 
ATOM   1878 C CD    . GLN A 1 274 ? 90.334  148.010 169.055 1.00 114.63 ? 274 GLN C CD    1 
ATOM   1879 O OE1   . GLN A 1 274 ? 89.786  148.047 167.954 1.00 113.91 ? 274 GLN C OE1   1 
ATOM   1880 N NE2   . GLN A 1 274 ? 89.974  148.799 170.060 1.00 118.31 ? 274 GLN C NE2   1 
ATOM   1881 N N     . GLY A 1 275 ? 92.438  142.470 168.655 1.00 111.50 ? 275 GLY C N     1 
ATOM   1882 C CA    . GLY A 1 275 ? 92.209  141.108 168.226 1.00 108.45 ? 275 GLY C CA    1 
ATOM   1883 C C     . GLY A 1 275 ? 93.266  140.544 167.303 1.00 110.02 ? 275 GLY C C     1 
ATOM   1884 O O     . GLY A 1 275 ? 93.112  139.409 166.835 1.00 105.98 ? 275 GLY C O     1 
ATOM   1885 N N     . ASP A 1 276 ? 94.332  141.296 167.024 1.00 110.75 ? 276 ASP C N     1 
ATOM   1886 C CA    . ASP A 1 276 ? 95.390  140.840 166.131 1.00 110.48 ? 276 ASP C CA    1 
ATOM   1887 C C     . ASP A 1 276 ? 94.823  140.510 164.753 1.00 111.92 ? 276 ASP C C     1 
ATOM   1888 O O     . ASP A 1 276 ? 94.625  141.409 163.930 1.00 105.03 ? 276 ASP C O     1 
ATOM   1889 C CB    . ASP A 1 276 ? 96.113  139.632 166.736 1.00 109.35 ? 276 ASP C CB    1 
ATOM   1890 C CG    . ASP A 1 276 ? 97.329  139.212 165.930 1.00 106.12 ? 276 ASP C CG    1 
ATOM   1891 O OD1   . ASP A 1 276 ? 97.523  139.740 164.815 1.00 103.45 ? 276 ASP C OD1   1 
ATOM   1892 O OD2   . ASP A 1 276 ? 98.092  138.349 166.411 1.00 104.21 ? 276 ASP C OD2   1 
ATOM   1893 N N     . GLY A 1 277 ? 94.558  139.232 164.489 1.00 110.95 ? 277 GLY C N     1 
ATOM   1894 C CA    . GLY A 1 277 ? 94.064  138.837 163.185 1.00 103.92 ? 277 GLY C CA    1 
ATOM   1895 C C     . GLY A 1 277 ? 95.071  138.972 162.067 1.00 100.79 ? 277 GLY C C     1 
ATOM   1896 O O     . GLY A 1 277 ? 94.685  138.969 160.896 1.00 99.02  ? 277 GLY C O     1 
ATOM   1897 N N     . SER A 1 278 ? 96.357  139.090 162.394 1.00 100.96 ? 278 SER C N     1 
ATOM   1898 C CA    . SER A 1 278 ? 97.457  139.233 161.447 1.00 97.59  ? 278 SER C CA    1 
ATOM   1899 C C     . SER A 1 278 ? 97.485  140.602 160.781 1.00 89.80  ? 278 SER C C     1 
ATOM   1900 O O     . SER A 1 278 ? 98.317  140.822 159.894 1.00 82.19  ? 278 SER C O     1 
ATOM   1901 C CB    . SER A 1 278 ? 97.423  138.156 160.353 1.00 93.64  ? 278 SER C CB    1 
ATOM   1902 O OG    . SER A 1 278 ? 97.023  136.905 160.882 1.00 98.91  ? 278 SER C OG    1 
ATOM   1903 N N     . ILE A 1 279 ? 96.613  141.527 161.171 1.00 87.37  ? 279 ILE C N     1 
ATOM   1904 C CA    . ILE A 1 279 ? 96.570  142.869 160.605 1.00 82.27  ? 279 ILE C CA    1 
ATOM   1905 C C     . ILE A 1 279 ? 96.702  143.869 161.742 1.00 74.03  ? 279 ILE C C     1 
ATOM   1906 O O     . ILE A 1 279 ? 95.946  143.809 162.719 1.00 78.73  ? 279 ILE C O     1 
ATOM   1907 C CB    . ILE A 1 279 ? 95.272  143.110 159.813 1.00 88.63  ? 279 ILE C CB    1 
ATOM   1908 C CG1   . ILE A 1 279 ? 95.196  142.158 158.618 1.00 85.33  ? 279 ILE C CG1   1 
ATOM   1909 C CG2   . ILE A 1 279 ? 95.191  144.558 159.347 1.00 80.60  ? 279 ILE C CG2   1 
ATOM   1910 C CD1   . ILE A 1 279 ? 93.927  141.334 158.576 1.00 85.24  ? 279 ILE C CD1   1 
ATOM   1911 N N     . GLY A 1 280 ? 97.656  144.783 161.614 1.00 67.19  ? 280 GLY C N     1 
ATOM   1912 C CA    . GLY A 1 280 ? 97.888  145.818 162.602 1.00 67.07  ? 280 GLY C CA    1 
ATOM   1913 C C     . GLY A 1 280 ? 97.909  147.182 161.945 1.00 64.00  ? 280 GLY C C     1 
ATOM   1914 O O     . GLY A 1 280 ? 97.110  147.486 161.064 1.00 69.34  ? 280 GLY C O     1 
ATOM   1915 N N     . VAL A 1 281 ? 98.846  148.017 162.391 1.00 63.92  ? 281 VAL C N     1 
ATOM   1916 C CA    . VAL A 1 281 ? 98.972  149.373 161.872 1.00 64.80  ? 281 VAL C CA    1 
ATOM   1917 C C     . VAL A 1 281 ? 100.415 149.828 162.024 1.00 64.60  ? 281 VAL C C     1 
ATOM   1918 O O     . VAL A 1 281 ? 101.121 149.427 162.953 1.00 67.48  ? 281 VAL C O     1 
ATOM   1919 C CB    . VAL A 1 281 ? 98.005  150.345 162.587 1.00 65.33  ? 281 VAL C CB    1 
ATOM   1920 C CG1   . VAL A 1 281 ? 98.309  150.408 164.073 1.00 67.37  ? 281 VAL C CG1   1 
ATOM   1921 C CG2   . VAL A 1 281 ? 98.087  151.729 161.964 1.00 64.88  ? 281 VAL C CG2   1 
ATOM   1922 N N     . VAL A 1 282 ? 100.850 150.672 161.096 1.00 58.17  ? 282 VAL C N     1 
ATOM   1923 C CA    . VAL A 1 282 ? 102.182 151.260 161.157 1.00 57.45  ? 282 VAL C CA    1 
ATOM   1924 C C     . VAL A 1 282 ? 102.147 152.448 162.106 1.00 62.20  ? 282 VAL C C     1 
ATOM   1925 O O     . VAL A 1 282 ? 101.252 153.296 162.024 1.00 68.58  ? 282 VAL C O     1 
ATOM   1926 C CB    . VAL A 1 282 ? 102.654 151.684 159.758 1.00 55.99  ? 282 VAL C CB    1 
ATOM   1927 C CG1   . VAL A 1 282 ? 104.078 152.210 159.814 1.00 54.87  ? 282 VAL C CG1   1 
ATOM   1928 C CG2   . VAL A 1 282 ? 102.545 150.525 158.790 1.00 57.74  ? 282 VAL C CG2   1 
ATOM   1929 N N     . VAL A 1 283 ? 103.116 152.507 163.018 1.00 59.99  ? 283 VAL C N     1 
ATOM   1930 C CA    . VAL A 1 283 ? 103.227 153.619 163.957 1.00 60.74  ? 283 VAL C CA    1 
ATOM   1931 C C     . VAL A 1 283 ? 104.451 154.480 163.702 1.00 63.29  ? 283 VAL C C     1 
ATOM   1932 O O     . VAL A 1 283 ? 104.564 155.559 164.306 1.00 70.62  ? 283 VAL C O     1 
ATOM   1933 C CB    . VAL A 1 283 ? 103.232 153.124 165.419 1.00 65.34  ? 283 VAL C CB    1 
ATOM   1934 C CG1   . VAL A 1 283 ? 101.921 152.426 165.744 1.00 65.83  ? 283 VAL C CG1   1 
ATOM   1935 C CG2   . VAL A 1 283 ? 104.411 152.196 165.667 1.00 65.49  ? 283 VAL C CG2   1 
ATOM   1936 N N     . GLY A 1 284 ? 105.361 154.055 162.838 1.00 61.50  ? 284 GLY C N     1 
ATOM   1937 C CA    . GLY A 1 284 ? 106.538 154.848 162.540 1.00 64.12  ? 284 GLY C CA    1 
ATOM   1938 C C     . GLY A 1 284 ? 107.325 154.198 161.427 1.00 59.22  ? 284 GLY C C     1 
ATOM   1939 O O     . GLY A 1 284 ? 107.028 153.082 160.992 1.00 60.45  ? 284 GLY C O     1 
ATOM   1940 N N     . LEU A 1 285 ? 108.342 154.925 160.963 1.00 59.93  ? 285 LEU C N     1 
ATOM   1941 C CA    . LEU A 1 285 ? 109.196 154.453 159.891 1.00 61.00  ? 285 LEU C CA    1 
ATOM   1942 C C     . LEU A 1 285 ? 110.631 154.845 160.229 1.00 59.05  ? 285 LEU C C     1 
ATOM   1943 O O     . LEU A 1 285 ? 110.882 156.010 160.584 1.00 60.17  ? 285 LEU C O     1 
ATOM   1944 C CB    . LEU A 1 285 ? 108.781 155.039 158.540 1.00 62.01  ? 285 LEU C CB    1 
ATOM   1945 C CG    . LEU A 1 285 ? 107.344 154.738 158.110 1.00 61.21  ? 285 LEU C CG    1 
ATOM   1946 C CD1   . LEU A 1 285 ? 106.941 155.630 156.952 1.00 65.07  ? 285 LEU C CD1   1 
ATOM   1947 C CD2   . LEU A 1 285 ? 107.188 153.275 157.740 1.00 53.55  ? 285 LEU C CD2   1 
ATOM   1948 N N     . PRO A 1 286 ? 111.585 153.924 160.128 1.00 56.13  ? 286 PRO C N     1 
ATOM   1949 C CA    . PRO A 1 286 ? 112.951 154.238 160.549 1.00 59.10  ? 286 PRO C CA    1 
ATOM   1950 C C     . PRO A 1 286 ? 113.587 155.311 159.680 1.00 58.30  ? 286 PRO C C     1 
ATOM   1951 O O     . PRO A 1 286 ? 113.275 155.455 158.496 1.00 56.85  ? 286 PRO C O     1 
ATOM   1952 C CB    . PRO A 1 286 ? 113.681 152.900 160.403 1.00 51.92  ? 286 PRO C CB    1 
ATOM   1953 C CG    . PRO A 1 286 ? 112.924 152.178 159.360 1.00 48.57  ? 286 PRO C CG    1 
ATOM   1954 C CD    . PRO A 1 286 ? 111.492 152.581 159.534 1.00 53.19  ? 286 PRO C CD    1 
ATOM   1955 N N     . LEU A 1 287 ? 114.491 156.069 160.290 1.00 60.54  ? 287 LEU C N     1 
ATOM   1956 C CA    . LEU A 1 287 ? 115.232 157.120 159.611 1.00 60.34  ? 287 LEU C CA    1 
ATOM   1957 C C     . LEU A 1 287 ? 116.601 156.606 159.180 1.00 61.24  ? 287 LEU C C     1 
ATOM   1958 O O     . LEU A 1 287 ? 117.047 155.529 159.578 1.00 54.82  ? 287 LEU C O     1 
ATOM   1959 C CB    . LEU A 1 287 ? 115.385 158.340 160.523 1.00 63.64  ? 287 LEU C CB    1 
ATOM   1960 C CG    . LEU A 1 287 ? 114.164 159.256 160.620 1.00 66.20  ? 287 LEU C CG    1 
ATOM   1961 C CD1   . LEU A 1 287 ? 114.138 159.962 161.964 1.00 67.56  ? 287 LEU C CD1   1 
ATOM   1962 C CD2   . LEU A 1 287 ? 114.158 160.264 159.485 1.00 65.00  ? 287 LEU C CD2   1 
ATOM   1963 N N     . GLN A 1 288 ? 117.272 157.405 158.351 1.00 71.82  ? 288 GLN C N     1 
ATOM   1964 C CA    . GLN A 1 288 ? 118.594 157.083 157.817 1.00 69.90  ? 288 GLN C CA    1 
ATOM   1965 C C     . GLN A 1 288 ? 118.584 155.796 156.997 1.00 64.99  ? 288 GLN C C     1 
ATOM   1966 O O     . GLN A 1 288 ? 119.615 155.129 156.867 1.00 61.87  ? 288 GLN C O     1 
ATOM   1967 C CB    . GLN A 1 288 ? 119.635 156.988 158.940 1.00 67.22  ? 288 GLN C CB    1 
ATOM   1968 C CG    . GLN A 1 288 ? 120.226 158.328 159.347 1.00 71.65  ? 288 GLN C CG    1 
ATOM   1969 C CD    . GLN A 1 288 ? 121.130 158.916 158.281 1.00 75.57  ? 288 GLN C CD    1 
ATOM   1970 O OE1   . GLN A 1 288 ? 121.267 158.360 157.192 1.00 68.01  ? 288 GLN C OE1   1 
ATOM   1971 N NE2   . GLN A 1 288 ? 121.750 160.049 158.589 1.00 77.79  ? 288 GLN C NE2   1 
ATOM   1972 N N     . ALA A 1 289 ? 117.434 155.442 156.432 1.00 63.90  ? 289 ALA C N     1 
ATOM   1973 C CA    . ALA A 1 289 ? 117.299 154.212 155.661 1.00 56.86  ? 289 ALA C CA    1 
ATOM   1974 C C     . ALA A 1 289 ? 118.301 154.172 154.515 1.00 54.24  ? 289 ALA C C     1 
ATOM   1975 O O     . ALA A 1 289 ? 119.107 153.246 154.417 1.00 52.68  ? 289 ALA C O     1 
ATOM   1976 C CB    . ALA A 1 289 ? 115.881 154.079 155.128 1.00 52.24  ? 289 ALA C CB    1 
ATOM   1977 N N     . THR A 1 316 ? 128.828 145.386 175.068 1.00 93.87  ? 316 THR C N     1 
ATOM   1978 C CA    . THR A 1 316 ? 127.946 146.249 175.843 1.00 96.55  ? 316 THR C CA    1 
ATOM   1979 C C     . THR A 1 316 ? 127.541 147.474 175.031 1.00 96.33  ? 316 THR C C     1 
ATOM   1980 O O     . THR A 1 316 ? 126.359 147.694 174.771 1.00 93.15  ? 316 THR C O     1 
ATOM   1981 C CB    . THR A 1 316 ? 128.614 146.712 177.152 1.00 100.89 ? 316 THR C CB    1 
ATOM   1982 O OG1   . THR A 1 316 ? 128.988 145.570 177.932 1.00 101.73 ? 316 THR C OG1   1 
ATOM   1983 C CG2   . THR A 1 316 ? 127.665 147.586 177.961 1.00 99.90  ? 316 THR C CG2   1 
ATOM   1984 N N     . ASN A 1 317 ? 128.537 148.269 174.632 1.00 97.03  ? 317 ASN C N     1 
ATOM   1985 C CA    . ASN A 1 317 ? 128.255 149.470 173.850 1.00 91.96  ? 317 ASN C CA    1 
ATOM   1986 C C     . ASN A 1 317 ? 127.636 149.120 172.504 1.00 88.83  ? 317 ASN C C     1 
ATOM   1987 O O     . ASN A 1 317 ? 126.718 149.804 172.038 1.00 84.63  ? 317 ASN C O     1 
ATOM   1988 C CB    . ASN A 1 317 ? 129.536 150.278 173.652 1.00 88.91  ? 317 ASN C CB    1 
ATOM   1989 C CG    . ASN A 1 317 ? 130.676 149.439 173.112 1.00 87.89  ? 317 ASN C CG    1 
ATOM   1990 O OD1   . ASN A 1 317 ? 130.494 148.644 172.191 1.00 86.32  ? 317 ASN C OD1   1 
ATOM   1991 N ND2   . ASN A 1 317 ? 131.862 149.611 173.686 1.00 85.08  ? 317 ASN C ND2   1 
ATOM   1992 N N     . LEU A 1 318 ? 128.125 148.057 171.862 1.00 87.10  ? 318 LEU C N     1 
ATOM   1993 C CA    . LEU A 1 318 ? 127.597 147.677 170.555 1.00 84.95  ? 318 LEU C CA    1 
ATOM   1994 C C     . LEU A 1 318 ? 126.107 147.371 170.633 1.00 82.24  ? 318 LEU C C     1 
ATOM   1995 O O     . LEU A 1 318 ? 125.326 147.838 169.797 1.00 78.55  ? 318 LEU C O     1 
ATOM   1996 C CB    . LEU A 1 318 ? 128.372 146.476 170.014 1.00 83.09  ? 318 LEU C CB    1 
ATOM   1997 C CG    . LEU A 1 318 ? 127.924 145.865 168.683 1.00 79.04  ? 318 LEU C CG    1 
ATOM   1998 C CD1   . LEU A 1 318 ? 127.436 146.921 167.710 1.00 77.13  ? 318 LEU C CD1   1 
ATOM   1999 C CD2   . LEU A 1 318 ? 129.066 145.079 168.065 1.00 80.13  ? 318 LEU C CD2   1 
ATOM   2000 N N     . LEU A 1 319 ? 125.689 146.602 171.640 1.00 80.64  ? 319 LEU C N     1 
ATOM   2001 C CA    . LEU A 1 319 ? 124.269 146.332 171.828 1.00 79.14  ? 319 LEU C CA    1 
ATOM   2002 C C     . LEU A 1 319 ? 123.502 147.548 172.325 1.00 76.95  ? 319 LEU C C     1 
ATOM   2003 O O     . LEU A 1 319 ? 122.270 147.497 172.385 1.00 75.41  ? 319 LEU C O     1 
ATOM   2004 C CB    . LEU A 1 319 ? 124.070 145.173 172.805 1.00 82.23  ? 319 LEU C CB    1 
ATOM   2005 C CG    . LEU A 1 319 ? 124.463 143.786 172.299 1.00 84.72  ? 319 LEU C CG    1 
ATOM   2006 C CD1   . LEU A 1 319 ? 124.241 142.744 173.383 1.00 93.11  ? 319 LEU C CD1   1 
ATOM   2007 C CD2   . LEU A 1 319 ? 123.685 143.425 171.043 1.00 77.31  ? 319 LEU C CD2   1 
ATOM   2008 N N     . GLU A 1 320 ? 124.192 148.626 172.696 1.00 77.33  ? 320 GLU C N     1 
ATOM   2009 C CA    . GLU A 1 320 ? 123.520 149.844 173.127 1.00 78.09  ? 320 GLU C CA    1 
ATOM   2010 C C     . GLU A 1 320 ? 123.104 150.731 171.963 1.00 75.56  ? 320 GLU C C     1 
ATOM   2011 O O     . GLU A 1 320 ? 122.313 151.658 172.167 1.00 74.72  ? 320 GLU C O     1 
ATOM   2012 C CB    . GLU A 1 320 ? 124.430 150.634 174.070 1.00 83.29  ? 320 GLU C CB    1 
ATOM   2013 C CG    . GLU A 1 320 ? 123.769 151.840 174.715 1.00 83.61  ? 320 GLU C CG    1 
ATOM   2014 C CD    . GLU A 1 320 ? 124.643 152.482 175.774 1.00 88.45  ? 320 GLU C CD    1 
ATOM   2015 O OE1   . GLU A 1 320 ? 125.785 152.015 175.967 1.00 84.59  ? 320 GLU C OE1   1 
ATOM   2016 O OE2   . GLU A 1 320 ? 124.186 153.447 176.420 1.00 95.74  ? 320 GLU C OE2   1 
ATOM   2017 N N     . GLU A 1 321 ? 123.602 150.467 170.756 1.00 75.41  ? 321 GLU C N     1 
ATOM   2018 C CA    . GLU A 1 321 ? 123.273 151.307 169.613 1.00 72.35  ? 321 GLU C CA    1 
ATOM   2019 C C     . GLU A 1 321 ? 121.768 151.321 169.380 1.00 69.10  ? 321 GLU C C     1 
ATOM   2020 O O     . GLU A 1 321 ? 121.095 150.292 169.486 1.00 66.81  ? 321 GLU C O     1 
ATOM   2021 C CB    . GLU A 1 321 ? 124.000 150.806 168.365 1.00 69.84  ? 321 GLU C CB    1 
ATOM   2022 C CG    . GLU A 1 321 ? 125.352 151.469 168.134 1.00 73.25  ? 321 GLU C CG    1 
ATOM   2023 C CD    . GLU A 1 321 ? 126.251 150.669 167.209 1.00 71.49  ? 321 GLU C CD    1 
ATOM   2024 O OE1   . GLU A 1 321 ? 126.085 149.434 167.135 1.00 66.52  ? 321 GLU C OE1   1 
ATOM   2025 O OE2   . GLU A 1 321 ? 127.127 151.274 166.558 1.00 69.22  ? 321 GLU C OE2   1 
ATOM   2026 N N     . CYS A 1 322 ? 121.241 152.500 169.063 1.00 66.72  ? 322 CYS C N     1 
ATOM   2027 C CA    . CYS A 1 322 ? 119.810 152.709 168.915 1.00 67.36  ? 322 CYS C CA    1 
ATOM   2028 C C     . CYS A 1 322 ? 119.486 153.148 167.495 1.00 70.93  ? 322 CYS C C     1 
ATOM   2029 O O     . CYS A 1 322 ? 120.292 153.804 166.830 1.00 76.18  ? 322 CYS C O     1 
ATOM   2030 C CB    . CYS A 1 322 ? 119.304 153.764 169.904 1.00 67.31  ? 322 CYS C CB    1 
ATOM   2031 S SG    . CYS A 1 322 ? 119.904 153.537 171.592 1.00 96.56  ? 322 CYS C SG    1 
ATOM   2032 N N     . ILE A 1 323 ? 118.297 152.773 167.037 1.00 68.96  ? 323 ILE C N     1 
ATOM   2033 C CA    . ILE A 1 323 ? 117.779 153.227 165.759 1.00 61.77  ? 323 ILE C CA    1 
ATOM   2034 C C     . ILE A 1 323 ? 116.813 154.373 166.017 1.00 66.43  ? 323 ILE C C     1 
ATOM   2035 O O     . ILE A 1 323 ? 116.308 154.560 167.127 1.00 73.29  ? 323 ILE C O     1 
ATOM   2036 C CB    . ILE A 1 323 ? 117.086 152.093 164.969 1.00 56.90  ? 323 ILE C CB    1 
ATOM   2037 C CG1   . ILE A 1 323 ? 115.981 151.449 165.807 1.00 62.25  ? 323 ILE C CG1   1 
ATOM   2038 C CG2   . ILE A 1 323 ? 118.098 151.048 164.548 1.00 58.98  ? 323 ILE C CG2   1 
ATOM   2039 C CD1   . ILE A 1 323 ? 114.709 151.198 165.036 1.00 60.08  ? 323 ILE C CD1   1 
ATOM   2040 N N     . ALA A 1 324 ? 116.551 155.156 164.978 1.00 63.97  ? 324 ALA C N     1 
ATOM   2041 C CA    . ALA A 1 324 ? 115.629 156.279 165.059 1.00 66.79  ? 324 ALA C CA    1 
ATOM   2042 C C     . ALA A 1 324 ? 114.324 155.906 164.374 1.00 64.01  ? 324 ALA C C     1 
ATOM   2043 O O     . ALA A 1 324 ? 114.332 155.414 163.242 1.00 64.87  ? 324 ALA C O     1 
ATOM   2044 C CB    . ALA A 1 324 ? 116.231 157.528 164.415 1.00 69.58  ? 324 ALA C CB    1 
ATOM   2045 N N     . ILE A 1 325 ? 113.210 156.133 165.063 1.00 66.20  ? 325 ILE C N     1 
ATOM   2046 C CA    . ILE A 1 325 ? 111.879 155.841 164.548 1.00 65.93  ? 325 ILE C CA    1 
ATOM   2047 C C     . ILE A 1 325 ? 111.087 157.138 164.524 1.00 70.97  ? 325 ILE C C     1 
ATOM   2048 O O     . ILE A 1 325 ? 110.975 157.820 165.550 1.00 76.91  ? 325 ILE C O     1 
ATOM   2049 C CB    . ILE A 1 325 ? 111.165 154.777 165.399 1.00 67.24  ? 325 ILE C CB    1 
ATOM   2050 C CG1   . ILE A 1 325 ? 111.851 153.422 165.222 1.00 66.57  ? 325 ILE C CG1   1 
ATOM   2051 C CG2   . ILE A 1 325 ? 109.693 154.697 165.022 1.00 67.35  ? 325 ILE C CG2   1 
ATOM   2052 C CD1   . ILE A 1 325 ? 111.319 152.337 166.132 1.00 63.48  ? 325 ILE C CD1   1 
ATOM   2053 N N     . GLN A 1 326 ? 110.542 157.475 163.359 1.00 68.62  ? 326 GLN C N     1 
ATOM   2054 C CA    . GLN A 1 326 ? 109.739 158.683 163.189 1.00 74.19  ? 326 GLN C CA    1 
ATOM   2055 C C     . GLN A 1 326 ? 108.301 158.344 163.560 1.00 75.73  ? 326 GLN C C     1 
ATOM   2056 O O     . GLN A 1 326 ? 107.562 157.761 162.764 1.00 78.42  ? 326 GLN C O     1 
ATOM   2057 C CB    . GLN A 1 326 ? 109.846 159.200 161.759 1.00 75.76  ? 326 GLN C CB    1 
ATOM   2058 C CG    . GLN A 1 326 ? 110.128 160.691 161.647 1.00 75.92  ? 326 GLN C CG    1 
ATOM   2059 C CD    . GLN A 1 326 ? 108.890 161.542 161.846 1.00 75.40  ? 326 GLN C CD    1 
ATOM   2060 O OE1   . GLN A 1 326 ? 107.769 161.036 161.857 1.00 75.81  ? 326 GLN C OE1   1 
ATOM   2061 N NE2   . GLN A 1 326 ? 109.089 162.845 162.006 1.00 76.15  ? 326 GLN C NE2   1 
ATOM   2062 N N     . LYS A 1 327 ? 107.903 158.708 164.775 1.00 74.94  ? 327 LYS C N     1 
ATOM   2063 C CA    . LYS A 1 327 ? 106.560 158.439 165.257 1.00 76.47  ? 327 LYS C CA    1 
ATOM   2064 C C     . LYS A 1 327 ? 105.651 159.630 164.963 1.00 83.27  ? 327 LYS C C     1 
ATOM   2065 O O     . LYS A 1 327 ? 106.071 160.647 164.408 1.00 85.40  ? 327 LYS C O     1 
ATOM   2066 C CB    . LYS A 1 327 ? 106.586 158.123 166.750 1.00 77.97  ? 327 LYS C CB    1 
ATOM   2067 C CG    . LYS A 1 327 ? 107.029 156.711 167.070 1.00 77.36  ? 327 LYS C CG    1 
ATOM   2068 C CD    . LYS A 1 327 ? 105.880 155.880 167.611 1.00 76.54  ? 327 LYS C CD    1 
ATOM   2069 C CE    . LYS A 1 327 ? 106.269 154.419 167.747 1.00 79.43  ? 327 LYS C CE    1 
ATOM   2070 N NZ    . LYS A 1 327 ? 105.193 153.610 168.382 1.00 77.23  ? 327 LYS C NZ    1 
ATOM   2071 N N     . GLN A 1 328 ? 104.379 159.500 165.344 1.00 86.33  ? 328 GLN C N     1 
ATOM   2072 C CA    . GLN A 1 328 ? 103.433 160.587 165.119 1.00 90.64  ? 328 GLN C CA    1 
ATOM   2073 C C     . GLN A 1 328 ? 103.843 161.837 165.888 1.00 91.54  ? 328 GLN C C     1 
ATOM   2074 O O     . GLN A 1 328 ? 103.747 162.954 165.367 1.00 90.88  ? 328 GLN C O     1 
ATOM   2075 C CB    . GLN A 1 328 ? 102.025 160.143 165.513 1.00 90.71  ? 328 GLN C CB    1 
ATOM   2076 C CG    . GLN A 1 328 ? 100.916 160.972 164.880 1.00 95.76  ? 328 GLN C CG    1 
ATOM   2077 C CD    . GLN A 1 328 ? 99.630  160.188 164.686 1.00 93.10  ? 328 GLN C CD    1 
ATOM   2078 O OE1   . GLN A 1 328 ? 99.587  158.976 164.898 1.00 90.97  ? 328 GLN C OE1   1 
ATOM   2079 N NE2   . GLN A 1 328 ? 98.574  160.879 164.276 1.00 91.88  ? 328 GLN C NE2   1 
ATOM   2080 N N     . ASP A 1 329 ? 104.309 161.671 167.127 1.00 94.30  ? 329 ASP C N     1 
ATOM   2081 C CA    . ASP A 1 329 ? 104.734 162.820 167.920 1.00 96.64  ? 329 ASP C CA    1 
ATOM   2082 C C     . ASP A 1 329 ? 106.086 163.341 167.446 1.00 99.28  ? 329 ASP C C     1 
ATOM   2083 O O     . ASP A 1 329 ? 106.209 164.497 167.025 1.00 101.11 ? 329 ASP C O     1 
ATOM   2084 C CB    . ASP A 1 329 ? 104.793 162.441 169.401 1.00 90.60  ? 329 ASP C CB    1 
ATOM   2085 C CG    . ASP A 1 329 ? 103.436 162.073 169.961 1.00 94.38  ? 329 ASP C CG    1 
ATOM   2086 O OD1   . ASP A 1 329 ? 102.436 162.187 169.221 1.00 95.52  ? 329 ASP C OD1   1 
ATOM   2087 O OD2   . ASP A 1 329 ? 103.367 161.676 171.143 1.00 97.52  ? 329 ASP C OD2   1 
ATOM   2088 N N     . GLY A 1 330 ? 107.113 162.500 167.504 1.00 96.31  ? 330 GLY C N     1 
ATOM   2089 C CA    . GLY A 1 330 ? 108.442 162.916 167.090 1.00 89.78  ? 330 GLY C CA    1 
ATOM   2090 C C     . GLY A 1 330 ? 109.393 161.741 167.084 1.00 83.13  ? 330 GLY C C     1 
ATOM   2091 O O     . GLY A 1 330 ? 109.052 160.630 167.499 1.00 80.23  ? 330 GLY C O     1 
ATOM   2092 N N     . VAL A 1 331 ? 110.609 162.012 166.605 1.00 80.03  ? 331 VAL C N     1 
ATOM   2093 C CA    . VAL A 1 331 ? 111.617 160.966 166.499 1.00 78.42  ? 331 VAL C CA    1 
ATOM   2094 C C     . VAL A 1 331 ? 111.920 160.401 167.877 1.00 75.95  ? 331 VAL C C     1 
ATOM   2095 O O     . VAL A 1 331 ? 112.036 161.139 168.864 1.00 75.16  ? 331 VAL C O     1 
ATOM   2096 C CB    . VAL A 1 331 ? 112.893 161.512 165.838 1.00 79.56  ? 331 VAL C CB    1 
ATOM   2097 C CG1   . VAL A 1 331 ? 113.899 160.392 165.617 1.00 76.63  ? 331 VAL C CG1   1 
ATOM   2098 C CG2   . VAL A 1 331 ? 112.561 162.200 164.525 1.00 78.46  ? 331 VAL C CG2   1 
ATOM   2099 N N     . ILE A 1 332 ? 112.050 159.079 167.951 1.00 76.19  ? 332 ILE C N     1 
ATOM   2100 C CA    . ILE A 1 332 ? 112.399 158.399 169.190 1.00 76.52  ? 332 ILE C CA    1 
ATOM   2101 C C     . ILE A 1 332 ? 113.550 157.444 168.916 1.00 75.23  ? 332 ILE C C     1 
ATOM   2102 O O     . ILE A 1 332 ? 113.723 156.948 167.799 1.00 76.65  ? 332 ILE C O     1 
ATOM   2103 C CB    . ILE A 1 332 ? 111.192 157.646 169.799 1.00 76.81  ? 332 ILE C CB    1 
ATOM   2104 C CG1   . ILE A 1 332 ? 111.075 156.232 169.223 1.00 70.34  ? 332 ILE C CG1   1 
ATOM   2105 C CG2   . ILE A 1 332 ? 109.910 158.427 169.553 1.00 77.99  ? 332 ILE C CG2   1 
ATOM   2106 C CD1   . ILE A 1 332 ? 109.823 155.498 169.658 1.00 70.69  ? 332 ILE C CD1   1 
ATOM   2107 N N     . LYS A 1 333 ? 114.346 157.189 169.950 1.00 76.51  ? 333 LYS C N     1 
ATOM   2108 C CA    . LYS A 1 333 ? 115.468 156.265 169.870 1.00 76.33  ? 333 LYS C CA    1 
ATOM   2109 C C     . LYS A 1 333 ? 115.043 154.934 170.475 1.00 74.87  ? 333 LYS C C     1 
ATOM   2110 O O     . LYS A 1 333 ? 114.624 154.883 171.636 1.00 76.59  ? 333 LYS C O     1 
ATOM   2111 C CB    . LYS A 1 333 ? 116.691 156.824 170.599 1.00 78.62  ? 333 LYS C CB    1 
ATOM   2112 C CG    . LYS A 1 333 ? 117.374 157.979 169.876 1.00 83.55  ? 333 LYS C CG    1 
ATOM   2113 C CD    . LYS A 1 333 ? 118.275 157.482 168.755 1.00 82.52  ? 333 LYS C CD    1 
ATOM   2114 C CE    . LYS A 1 333 ? 118.930 158.634 168.005 1.00 86.11  ? 333 LYS C CE    1 
ATOM   2115 N NZ    . LYS A 1 333 ? 120.121 159.173 168.720 1.00 89.11  ? 333 LYS C NZ    1 
ATOM   2116 N N     . CYS A 1 334 ? 115.146 153.868 169.689 1.00 71.54  ? 334 CYS C N     1 
ATOM   2117 C CA    . CYS A 1 334 ? 114.765 152.528 170.115 1.00 66.97  ? 334 CYS C CA    1 
ATOM   2118 C C     . CYS A 1 334 ? 116.004 151.646 170.158 1.00 64.98  ? 334 CYS C C     1 
ATOM   2119 O O     . CYS A 1 334 ? 116.741 151.557 169.170 1.00 65.95  ? 334 CYS C O     1 
ATOM   2120 C CB    . CYS A 1 334 ? 113.721 151.933 169.171 1.00 67.30  ? 334 CYS C CB    1 
ATOM   2121 S SG    . CYS A 1 334 ? 112.492 150.899 169.992 1.00 90.67  ? 334 CYS C SG    1 
ATOM   2122 N N     . LYS A 1 335 ? 116.230 151.002 171.300 1.00 66.26  ? 335 LYS C N     1 
ATOM   2123 C CA    . LYS A 1 335 ? 117.409 150.161 171.461 1.00 67.65  ? 335 LYS C CA    1 
ATOM   2124 C C     . LYS A 1 335 ? 117.365 148.991 170.489 1.00 58.88  ? 335 LYS C C     1 
ATOM   2125 O O     . LYS A 1 335 ? 116.313 148.392 170.258 1.00 61.31  ? 335 LYS C O     1 
ATOM   2126 C CB    . LYS A 1 335 ? 117.496 149.647 172.898 1.00 69.68  ? 335 LYS C CB    1 
ATOM   2127 C CG    . LYS A 1 335 ? 118.624 148.656 173.139 1.00 66.76  ? 335 LYS C CG    1 
ATOM   2128 C CD    . LYS A 1 335 ? 118.686 148.225 174.594 1.00 64.74  ? 335 LYS C CD    1 
ATOM   2129 C CE    . LYS A 1 335 ? 119.664 147.077 174.787 1.00 64.34  ? 335 LYS C CE    1 
ATOM   2130 N NZ    . LYS A 1 335 ? 119.842 146.730 176.223 1.00 66.25  ? 335 LYS C NZ    1 
ATOM   2131 N N     . ARG A 1 336 ? 118.521 148.661 169.921 1.00 55.22  ? 336 ARG C N     1 
ATOM   2132 C CA    . ARG A 1 336 ? 118.600 147.526 169.017 1.00 61.37  ? 336 ARG C CA    1 
ATOM   2133 C C     . ARG A 1 336 ? 118.461 146.222 169.791 1.00 58.32  ? 336 ARG C C     1 
ATOM   2134 O O     . ARG A 1 336 ? 118.879 146.109 170.945 1.00 60.18  ? 336 ARG C O     1 
ATOM   2135 C CB    . ARG A 1 336 ? 119.918 147.544 168.244 1.00 63.52  ? 336 ARG C CB    1 
ATOM   2136 C CG    . ARG A 1 336 ? 121.028 146.698 168.849 1.00 61.94  ? 336 ARG C CG    1 
ATOM   2137 C CD    . ARG A 1 336 ? 122.319 146.865 168.074 1.00 62.51  ? 336 ARG C CD    1 
ATOM   2138 N NE    . ARG A 1 336 ? 122.212 146.301 166.735 1.00 61.37  ? 336 ARG C NE    1 
ATOM   2139 C CZ    . ARG A 1 336 ? 123.205 146.248 165.859 1.00 61.85  ? 336 ARG C CZ    1 
ATOM   2140 N NH1   . ARG A 1 336 ? 124.406 146.721 166.147 1.00 65.55  ? 336 ARG C NH1   1 
ATOM   2141 N NH2   . ARG A 1 336 ? 122.988 145.706 164.666 1.00 57.97  ? 336 ARG C NH2   1 
ATOM   2142 N N     . SER A 1 337 ? 117.868 145.226 169.138 1.00 55.17  ? 337 SER C N     1 
ATOM   2143 C CA    . SER A 1 337 ? 117.658 143.930 169.767 1.00 58.26  ? 337 SER C CA    1 
ATOM   2144 C C     . SER A 1 337 ? 118.822 142.977 169.547 1.00 57.90  ? 337 SER C C     1 
ATOM   2145 O O     . SER A 1 337 ? 119.039 142.079 170.367 1.00 61.53  ? 337 SER C O     1 
ATOM   2146 C CB    . SER A 1 337 ? 116.372 143.290 169.240 1.00 63.80  ? 337 SER C CB    1 
ATOM   2147 O OG    . SER A 1 337 ? 115.274 143.585 170.085 1.00 69.62  ? 337 SER C OG    1 
ATOM   2148 N N     . GLY A 1 338 ? 119.573 143.145 168.463 1.00 58.63  ? 338 GLY C N     1 
ATOM   2149 C CA    . GLY A 1 338 ? 120.705 142.290 168.187 1.00 63.94  ? 338 GLY C CA    1 
ATOM   2150 C C     . GLY A 1 338 ? 120.361 140.952 167.574 1.00 63.11  ? 338 GLY C C     1 
ATOM   2151 O O     . GLY A 1 338 ? 121.271 140.150 167.334 1.00 63.63  ? 338 GLY C O     1 
ATOM   2152 N N     . LYS A 1 339 ? 119.084 140.683 167.310 1.00 63.00  ? 339 LYS C N     1 
ATOM   2153 C CA    . LYS A 1 339 ? 118.643 139.434 166.709 1.00 63.85  ? 339 LYS C CA    1 
ATOM   2154 C C     . LYS A 1 339 ? 118.042 139.712 165.340 1.00 58.71  ? 339 LYS C C     1 
ATOM   2155 O O     . LYS A 1 339 ? 117.278 140.666 165.168 1.00 60.28  ? 339 LYS C O     1 
ATOM   2156 C CB    . LYS A 1 339 ? 117.616 138.728 167.596 1.00 64.76  ? 339 LYS C CB    1 
ATOM   2157 C CG    . LYS A 1 339 ? 118.222 138.050 168.811 1.00 70.18  ? 339 LYS C CG    1 
ATOM   2158 C CD    . LYS A 1 339 ? 117.312 136.972 169.384 1.00 75.02  ? 339 LYS C CD    1 
ATOM   2159 C CE    . LYS A 1 339 ? 115.886 137.461 169.579 1.00 73.51  ? 339 LYS C CE    1 
ATOM   2160 N NZ    . LYS A 1 339 ? 115.829 138.669 170.447 1.00 71.71  ? 339 LYS C NZ    1 
ATOM   2161 N N     . SER A 1 340 ? 118.388 138.872 164.369 1.00 55.48  ? 340 SER C N     1 
ATOM   2162 C CA    . SER A 1 340 ? 117.903 139.061 163.011 1.00 50.61  ? 340 SER C CA    1 
ATOM   2163 C C     . SER A 1 340 ? 116.386 138.944 162.961 1.00 51.90  ? 340 SER C C     1 
ATOM   2164 O O     . SER A 1 340 ? 115.773 138.178 163.708 1.00 62.81  ? 340 SER C O     1 
ATOM   2165 C CB    . SER A 1 340 ? 118.532 138.030 162.077 1.00 56.31  ? 340 SER C CB    1 
ATOM   2166 O OG    . SER A 1 340 ? 118.682 136.782 162.727 1.00 59.09  ? 340 SER C OG    1 
ATOM   2167 N N     . LEU A 1 341 ? 115.777 139.720 162.062 1.00 48.55  ? 341 LEU C N     1 
ATOM   2168 C CA    . LEU A 1 341 ? 114.329 139.662 161.904 1.00 48.72  ? 341 LEU C CA    1 
ATOM   2169 C C     . LEU A 1 341 ? 113.875 138.246 161.583 1.00 56.81  ? 341 LEU C C     1 
ATOM   2170 O O     . LEU A 1 341 ? 112.834 137.795 162.070 1.00 61.86  ? 341 LEU C O     1 
ATOM   2171 C CB    . LEU A 1 341 ? 113.880 140.625 160.807 1.00 44.37  ? 341 LEU C CB    1 
ATOM   2172 C CG    . LEU A 1 341 ? 113.584 142.055 161.250 1.00 41.06  ? 341 LEU C CG    1 
ATOM   2173 C CD1   . LEU A 1 341 ? 113.444 142.968 160.047 1.00 43.41  ? 341 LEU C CD1   1 
ATOM   2174 C CD2   . LEU A 1 341 ? 112.331 142.093 162.100 1.00 42.55  ? 341 LEU C CD2   1 
ATOM   2175 N N     . TYR A 1 342 ? 114.643 137.530 160.762 1.00 58.40  ? 342 TYR C N     1 
ATOM   2176 C CA    . TYR A 1 342 ? 114.318 136.138 160.473 1.00 61.03  ? 342 TYR C CA    1 
ATOM   2177 C C     . TYR A 1 342 ? 114.321 135.303 161.748 1.00 63.31  ? 342 TYR C C     1 
ATOM   2178 O O     . TYR A 1 342 ? 113.371 134.560 162.022 1.00 64.40  ? 342 TYR C O     1 
ATOM   2179 C CB    . TYR A 1 342 ? 115.317 135.583 159.459 1.00 61.08  ? 342 TYR C CB    1 
ATOM   2180 C CG    . TYR A 1 342 ? 115.317 134.079 159.331 1.00 67.37  ? 342 TYR C CG    1 
ATOM   2181 C CD1   . TYR A 1 342 ? 114.154 133.384 159.041 1.00 70.04  ? 342 TYR C CD1   1 
ATOM   2182 C CD2   . TYR A 1 342 ? 116.489 133.355 159.489 1.00 70.86  ? 342 TYR C CD2   1 
ATOM   2183 C CE1   . TYR A 1 342 ? 114.157 132.008 158.917 1.00 71.46  ? 342 TYR C CE1   1 
ATOM   2184 C CE2   . TYR A 1 342 ? 116.503 131.983 159.366 1.00 73.64  ? 342 TYR C CE2   1 
ATOM   2185 C CZ    . TYR A 1 342 ? 115.336 131.314 159.081 1.00 74.70  ? 342 TYR C CZ    1 
ATOM   2186 O OH    . TYR A 1 342 ? 115.354 129.944 158.960 1.00 76.13  ? 342 TYR C OH    1 
ATOM   2187 N N     . HIS A 1 343 ? 115.381 135.429 162.550 1.00 65.75  ? 343 HIS C N     1 
ATOM   2188 C CA    . HIS A 1 343 ? 115.468 134.670 163.794 1.00 68.13  ? 343 HIS C CA    1 
ATOM   2189 C C     . HIS A 1 343 ? 114.376 135.083 164.774 1.00 63.85  ? 343 HIS C C     1 
ATOM   2190 O O     . HIS A 1 343 ? 113.774 134.231 165.436 1.00 67.13  ? 343 HIS C O     1 
ATOM   2191 C CB    . HIS A 1 343 ? 116.848 134.860 164.422 1.00 71.86  ? 343 HIS C CB    1 
ATOM   2192 C CG    . HIS A 1 343 ? 117.039 134.110 165.702 1.00 79.45  ? 343 HIS C CG    1 
ATOM   2193 N ND1   . HIS A 1 343 ? 116.488 134.522 166.896 1.00 80.42  ? 343 HIS C ND1   1 
ATOM   2194 C CD2   . HIS A 1 343 ? 117.724 132.975 165.976 1.00 85.11  ? 343 HIS C CD2   1 
ATOM   2195 C CE1   . HIS A 1 343 ? 116.823 133.672 167.850 1.00 80.86  ? 343 HIS C CE1   1 
ATOM   2196 N NE2   . HIS A 1 343 ? 117.574 132.724 167.319 1.00 87.27  ? 343 HIS C NE2   1 
ATOM   2197 N N     . CYS A 1 344 ? 114.115 136.386 164.892 1.00 59.32  ? 344 CYS C N     1 
ATOM   2198 C CA    . CYS A 1 344 ? 113.085 136.842 165.819 1.00 59.71  ? 344 CYS C CA    1 
ATOM   2199 C C     . CYS A 1 344 ? 111.713 136.317 165.419 1.00 66.45  ? 344 CYS C C     1 
ATOM   2200 O O     . CYS A 1 344 ? 110.939 135.864 166.271 1.00 72.15  ? 344 CYS C O     1 
ATOM   2201 C CB    . CYS A 1 344 ? 113.077 138.368 165.884 1.00 57.58  ? 344 CYS C CB    1 
ATOM   2202 S SG    . CYS A 1 344 ? 111.547 139.069 166.530 1.00 75.44  ? 344 CYS C SG    1 
ATOM   2203 N N     . LEU A 1 345 ? 111.393 136.364 164.124 1.00 64.73  ? 345 LEU C N     1 
ATOM   2204 C CA    . LEU A 1 345 ? 110.112 135.842 163.663 1.00 65.52  ? 345 LEU C CA    1 
ATOM   2205 C C     . LEU A 1 345 ? 110.024 134.336 163.869 1.00 67.63  ? 345 LEU C C     1 
ATOM   2206 O O     . LEU A 1 345 ? 108.971 133.818 164.256 1.00 65.83  ? 345 LEU C O     1 
ATOM   2207 C CB    . LEU A 1 345 ? 109.900 136.199 162.191 1.00 61.83  ? 345 LEU C CB    1 
ATOM   2208 C CG    . LEU A 1 345 ? 109.698 137.686 161.892 1.00 55.21  ? 345 LEU C CG    1 
ATOM   2209 C CD1   . LEU A 1 345 ? 109.897 137.956 160.416 1.00 48.70  ? 345 LEU C CD1   1 
ATOM   2210 C CD2   . LEU A 1 345 ? 108.324 138.151 162.338 1.00 53.72  ? 345 LEU C CD2   1 
ATOM   2211 N N     . LYS A 1 346 ? 111.118 133.613 163.615 1.00 69.96  ? 346 LYS C N     1 
ATOM   2212 C CA    . LYS A 1 346 ? 111.115 132.175 163.856 1.00 70.65  ? 346 LYS C CA    1 
ATOM   2213 C C     . LYS A 1 346 ? 110.859 131.868 165.325 1.00 71.84  ? 346 LYS C C     1 
ATOM   2214 O O     . LYS A 1 346 ? 110.081 130.965 165.653 1.00 69.81  ? 346 LYS C O     1 
ATOM   2215 C CB    . LYS A 1 346 ? 112.445 131.569 163.408 1.00 70.51  ? 346 LYS C CB    1 
ATOM   2216 C CG    . LYS A 1 346 ? 112.440 130.052 163.318 1.00 71.62  ? 346 LYS C CG    1 
ATOM   2217 C CD    . LYS A 1 346 ? 113.306 129.554 162.169 1.00 72.24  ? 346 LYS C CD    1 
ATOM   2218 C CE    . LYS A 1 346 ? 112.619 129.729 160.823 1.00 72.56  ? 346 LYS C CE    1 
ATOM   2219 N NZ    . LYS A 1 346 ? 111.403 128.880 160.697 1.00 75.95  ? 346 LYS C NZ    1 
ATOM   2220 N N     . GLU A 1 347 ? 111.506 132.612 166.225 1.00 74.41  ? 347 GLU C N     1 
ATOM   2221 C CA    . GLU A 1 347 ? 111.318 132.378 167.653 1.00 73.05  ? 347 GLU C CA    1 
ATOM   2222 C C     . GLU A 1 347 ? 109.893 132.701 168.082 1.00 75.42  ? 347 GLU C C     1 
ATOM   2223 O O     . GLU A 1 347 ? 109.285 131.946 168.849 1.00 76.35  ? 347 GLU C O     1 
ATOM   2224 C CB    . GLU A 1 347 ? 112.324 133.206 168.454 1.00 72.22  ? 347 GLU C CB    1 
ATOM   2225 C CG    . GLU A 1 347 ? 112.043 133.272 169.949 1.00 76.98  ? 347 GLU C CG    1 
ATOM   2226 C CD    . GLU A 1 347 ? 111.111 134.407 170.330 1.00 79.96  ? 347 GLU C CD    1 
ATOM   2227 O OE1   . GLU A 1 347 ? 111.183 135.484 169.701 1.00 79.11  ? 347 GLU C OE1   1 
ATOM   2228 O OE2   . GLU A 1 347 ? 110.300 134.221 171.261 1.00 77.56  ? 347 GLU C OE2   1 
ATOM   2229 N N     . THR A 1 348 ? 109.344 133.815 167.600 1.00 75.80  ? 348 THR C N     1 
ATOM   2230 C CA    . THR A 1 348 ? 108.006 134.230 168.002 1.00 78.02  ? 348 THR C CA    1 
ATOM   2231 C C     . THR A 1 348 ? 106.905 133.458 167.286 1.00 77.39  ? 348 THR C C     1 
ATOM   2232 O O     . THR A 1 348 ? 105.733 133.611 167.645 1.00 75.05  ? 348 THR C O     1 
ATOM   2233 C CB    . THR A 1 348 ? 107.824 135.731 167.752 1.00 78.73  ? 348 THR C CB    1 
ATOM   2234 O OG1   . THR A 1 348 ? 106.806 136.244 168.621 1.00 80.91  ? 348 THR C OG1   1 
ATOM   2235 C CG2   . THR A 1 348 ? 107.436 136.000 166.304 1.00 75.01  ? 348 THR C CG2   1 
ATOM   2236 N N     . ALA A 1 349 ? 107.246 132.638 166.289 1.00 78.65  ? 349 ALA C N     1 
ATOM   2237 C CA    . ALA A 1 349 ? 106.232 131.859 165.590 1.00 78.59  ? 349 ALA C CA    1 
ATOM   2238 C C     . ALA A 1 349 ? 105.541 130.862 166.508 1.00 82.09  ? 349 ALA C C     1 
ATOM   2239 O O     . ALA A 1 349 ? 104.407 130.459 166.225 1.00 79.98  ? 349 ALA C O     1 
ATOM   2240 C CB    . ALA A 1 349 ? 106.858 131.124 164.405 1.00 72.34  ? 349 ALA C CB    1 
ATOM   2241 N N     . GLY A 1 350 ? 106.192 130.455 167.593 1.00 88.20  ? 350 GLY C N     1 
ATOM   2242 C CA    . GLY A 1 350 ? 105.608 129.506 168.522 1.00 85.06  ? 350 GLY C CA    1 
ATOM   2243 C C     . GLY A 1 350 ? 106.646 128.840 169.405 1.00 79.30  ? 350 GLY C C     1 
ATOM   2244 O O     . GLY A 1 350 ? 107.836 128.839 169.089 1.00 72.20  ? 350 GLY C O     1 
ATOM   2245 N N     . GLU B 1 34  ? 123.293 90.655  142.774 1.00 106.00 ? 34  GLU D N     1 
ATOM   2246 C CA    . GLU B 1 34  ? 124.007 90.615  144.045 1.00 102.90 ? 34  GLU D CA    1 
ATOM   2247 C C     . GLU B 1 34  ? 124.522 92.000  144.418 1.00 97.20  ? 34  GLU D C     1 
ATOM   2248 O O     . GLU B 1 34  ? 124.673 92.317  145.597 1.00 95.70  ? 34  GLU D O     1 
ATOM   2249 C CB    . GLU B 1 34  ? 125.158 89.623  143.975 1.00 98.15  ? 34  GLU D CB    1 
ATOM   2250 N N     . LEU B 1 35  ? 124.794 92.818  143.407 1.00 92.76  ? 35  LEU D N     1 
ATOM   2251 C CA    . LEU B 1 35  ? 125.306 94.165  143.594 1.00 90.01  ? 35  LEU D CA    1 
ATOM   2252 C C     . LEU B 1 35  ? 124.553 95.116  142.677 1.00 88.47  ? 35  LEU D C     1 
ATOM   2253 O O     . LEU B 1 35  ? 124.034 94.694  141.637 1.00 93.57  ? 35  LEU D O     1 
ATOM   2254 C CB    . LEU B 1 35  ? 126.809 94.245  143.286 1.00 90.66  ? 35  LEU D CB    1 
ATOM   2255 C CG    . LEU B 1 35  ? 127.747 93.687  144.355 1.00 92.18  ? 35  LEU D CG    1 
ATOM   2256 C CD1   . LEU B 1 35  ? 129.089 93.323  143.743 1.00 91.61  ? 35  LEU D CD1   1 
ATOM   2257 C CD2   . LEU B 1 35  ? 127.927 94.685  145.482 1.00 86.30  ? 35  LEU D CD2   1 
ATOM   2258 N N     . PRO B 1 36  ? 124.473 96.397  143.033 1.00 81.38  ? 36  PRO D N     1 
ATOM   2259 C CA    . PRO B 1 36  ? 123.909 97.378  142.101 1.00 82.32  ? 36  PRO D CA    1 
ATOM   2260 C C     . PRO B 1 36  ? 124.713 97.427  140.811 1.00 82.31  ? 36  PRO D C     1 
ATOM   2261 O O     . PRO B 1 36  ? 125.795 96.850  140.689 1.00 82.91  ? 36  PRO D O     1 
ATOM   2262 C CB    . PRO B 1 36  ? 123.990 98.701  142.871 1.00 80.25  ? 36  PRO D CB    1 
ATOM   2263 C CG    . PRO B 1 36  ? 124.046 98.310  144.301 1.00 78.32  ? 36  PRO D CG    1 
ATOM   2264 C CD    . PRO B 1 36  ? 124.758 96.990  144.351 1.00 78.81  ? 36  PRO D CD    1 
ATOM   2265 N N     . ARG B 1 37  ? 124.158 98.134  139.825 1.00 84.13  ? 37  ARG D N     1 
ATOM   2266 C CA    . ARG B 1 37  ? 124.815 98.218  138.525 1.00 87.62  ? 37  ARG D CA    1 
ATOM   2267 C C     . ARG B 1 37  ? 126.154 98.938  138.624 1.00 87.04  ? 37  ARG D C     1 
ATOM   2268 O O     . ARG B 1 37  ? 127.136 98.521  138.002 1.00 85.81  ? 37  ARG D O     1 
ATOM   2269 C CB    . ARG B 1 37  ? 123.904 98.922  137.521 1.00 91.42  ? 37  ARG D CB    1 
ATOM   2270 C CG    . ARG B 1 37  ? 124.336 98.756  136.073 1.00 89.18  ? 37  ARG D CG    1 
ATOM   2271 C CD    . ARG B 1 37  ? 123.893 97.417  135.503 1.00 90.02  ? 37  ARG D CD    1 
ATOM   2272 N NE    . ARG B 1 37  ? 124.436 97.182  134.169 1.00 94.58  ? 37  ARG D NE    1 
ATOM   2273 C CZ    . ARG B 1 37  ? 125.560 96.526  133.913 1.00 92.75  ? 37  ARG D CZ    1 
ATOM   2274 N NH1   . ARG B 1 37  ? 126.309 96.025  134.882 1.00 89.93  ? 37  ARG D NH1   1 
ATOM   2275 N NH2   . ARG B 1 37  ? 125.946 96.370  132.650 1.00 88.46  ? 37  ARG D NH2   1 
ATOM   2276 N N     . ASN B 1 38  ? 126.214 100.024 139.398 1.00 85.87  ? 38  ASN D N     1 
ATOM   2277 C CA    . ASN B 1 38  ? 127.441 100.812 139.471 1.00 82.07  ? 38  ASN D CA    1 
ATOM   2278 C C     . ASN B 1 38  ? 128.586 99.994  140.053 1.00 78.42  ? 38  ASN D C     1 
ATOM   2279 O O     . ASN B 1 38  ? 129.689 99.956  139.494 1.00 80.35  ? 38  ASN D O     1 
ATOM   2280 C CB    . ASN B 1 38  ? 127.204 102.067 140.309 1.00 78.14  ? 38  ASN D CB    1 
ATOM   2281 C CG    . ASN B 1 38  ? 126.089 102.929 139.762 1.00 81.04  ? 38  ASN D CG    1 
ATOM   2282 O OD1   . ASN B 1 38  ? 125.116 102.423 139.204 1.00 82.03  ? 38  ASN D OD1   1 
ATOM   2283 N ND2   . ASN B 1 38  ? 126.226 104.240 139.917 1.00 79.20  ? 38  ASN D ND2   1 
ATOM   2284 N N     . LEU B 1 39  ? 128.345 99.338  141.186 1.00 75.56  ? 39  LEU D N     1 
ATOM   2285 C CA    . LEU B 1 39  ? 129.404 98.562  141.819 1.00 77.29  ? 39  LEU D CA    1 
ATOM   2286 C C     . LEU B 1 39  ? 129.830 97.399  140.935 1.00 77.76  ? 39  LEU D C     1 
ATOM   2287 O O     . LEU B 1 39  ? 131.026 97.108  140.809 1.00 78.80  ? 39  LEU D O     1 
ATOM   2288 C CB    . LEU B 1 39  ? 128.937 98.059  143.182 1.00 80.95  ? 39  LEU D CB    1 
ATOM   2289 C CG    . LEU B 1 39  ? 128.214 99.086  144.056 1.00 81.96  ? 39  LEU D CG    1 
ATOM   2290 C CD1   . LEU B 1 39  ? 128.115 98.585  145.484 1.00 79.45  ? 39  LEU D CD1   1 
ATOM   2291 C CD2   . LEU B 1 39  ? 128.913 100.438 144.010 1.00 76.81  ? 39  LEU D CD2   1 
ATOM   2292 N N     . GLU B 1 40  ? 128.864 96.723  140.311 1.00 78.09  ? 40  GLU D N     1 
ATOM   2293 C CA    . GLU B 1 40  ? 129.197 95.608  139.433 1.00 81.58  ? 40  GLU D CA    1 
ATOM   2294 C C     . GLU B 1 40  ? 130.035 96.075  138.251 1.00 81.98  ? 40  GLU D C     1 
ATOM   2295 O O     . GLU B 1 40  ? 131.010 95.415  137.875 1.00 81.16  ? 40  GLU D O     1 
ATOM   2296 C CB    . GLU B 1 40  ? 127.917 94.923  138.951 1.00 85.63  ? 40  GLU D CB    1 
ATOM   2297 C CG    . GLU B 1 40  ? 128.076 94.102  137.673 1.00 91.04  ? 40  GLU D CG    1 
ATOM   2298 C CD    . GLU B 1 40  ? 129.255 93.149  137.723 1.00 93.03  ? 40  GLU D CD    1 
ATOM   2299 O OE1   . GLU B 1 40  ? 129.692 92.795  138.837 1.00 96.04  ? 40  GLU D OE1   1 
ATOM   2300 O OE2   . GLU B 1 40  ? 129.751 92.762  136.644 1.00 85.61  ? 40  GLU D OE2   1 
ATOM   2301 N N     . VAL B 1 41  ? 129.675 97.209  137.651 1.00 81.80  ? 41  VAL D N     1 
ATOM   2302 C CA    . VAL B 1 41  ? 130.412 97.677  136.483 1.00 79.28  ? 41  VAL D CA    1 
ATOM   2303 C C     . VAL B 1 41  ? 131.812 98.120  136.883 1.00 75.44  ? 41  VAL D C     1 
ATOM   2304 O O     . VAL B 1 41  ? 132.779 97.881  136.153 1.00 75.86  ? 41  VAL D O     1 
ATOM   2305 C CB    . VAL B 1 41  ? 129.636 98.796  135.761 1.00 80.50  ? 41  VAL D CB    1 
ATOM   2306 C CG1   . VAL B 1 41  ? 129.989 100.169 136.312 1.00 76.69  ? 41  VAL D CG1   1 
ATOM   2307 C CG2   . VAL B 1 41  ? 129.907 98.740  134.271 1.00 82.79  ? 41  VAL D CG2   1 
ATOM   2308 N N     . PHE B 1 42  ? 131.952 98.765  138.045 1.00 70.72  ? 42  PHE D N     1 
ATOM   2309 C CA    . PHE B 1 42  ? 133.286 99.142  138.499 1.00 67.22  ? 42  PHE D CA    1 
ATOM   2310 C C     . PHE B 1 42  ? 134.143 97.912  138.761 1.00 72.86  ? 42  PHE D C     1 
ATOM   2311 O O     . PHE B 1 42  ? 135.324 97.879  138.394 1.00 75.42  ? 42  PHE D O     1 
ATOM   2312 C CB    . PHE B 1 42  ? 133.205 100.005 139.755 1.00 64.85  ? 42  PHE D CB    1 
ATOM   2313 C CG    . PHE B 1 42  ? 134.548 100.433 140.276 1.00 64.99  ? 42  PHE D CG    1 
ATOM   2314 C CD1   . PHE B 1 42  ? 135.147 101.591 139.818 1.00 63.17  ? 42  PHE D CD1   1 
ATOM   2315 C CD2   . PHE B 1 42  ? 135.215 99.672  141.217 1.00 63.64  ? 42  PHE D CD2   1 
ATOM   2316 C CE1   . PHE B 1 42  ? 136.380 101.984 140.293 1.00 55.68  ? 42  PHE D CE1   1 
ATOM   2317 C CE2   . PHE B 1 42  ? 136.448 100.062 141.694 1.00 58.91  ? 42  PHE D CE2   1 
ATOM   2318 C CZ    . PHE B 1 42  ? 137.030 101.218 141.231 1.00 54.89  ? 42  PHE D CZ    1 
ATOM   2319 N N     . ASN B 1 43  ? 133.571 96.890  139.403 1.00 75.10  ? 43  ASN D N     1 
ATOM   2320 C CA    . ASN B 1 43  ? 134.322 95.662  139.635 1.00 73.78  ? 43  ASN D CA    1 
ATOM   2321 C C     . ASN B 1 43  ? 134.734 95.019  138.318 1.00 75.33  ? 43  ASN D C     1 
ATOM   2322 O O     . ASN B 1 43  ? 135.882 94.590  138.159 1.00 74.73  ? 43  ASN D O     1 
ATOM   2323 C CB    . ASN B 1 43  ? 133.492 94.687  140.468 1.00 73.99  ? 43  ASN D CB    1 
ATOM   2324 C CG    . ASN B 1 43  ? 133.508 95.021  141.945 1.00 74.28  ? 43  ASN D CG    1 
ATOM   2325 O OD1   . ASN B 1 43  ? 134.385 94.575  142.684 1.00 76.01  ? 43  ASN D OD1   1 
ATOM   2326 N ND2   . ASN B 1 43  ? 132.531 95.805  142.385 1.00 76.52  ? 43  ASN D ND2   1 
ATOM   2327 N N     . GLU B 1 44  ? 133.813 94.952  137.355 1.00 76.25  ? 44  GLU D N     1 
ATOM   2328 C CA    . GLU B 1 44  ? 134.136 94.360  136.062 1.00 77.06  ? 44  GLU D CA    1 
ATOM   2329 C C     . GLU B 1 44  ? 135.258 95.129  135.380 1.00 77.00  ? 44  GLU D C     1 
ATOM   2330 O O     . GLU B 1 44  ? 136.210 94.535  134.863 1.00 78.84  ? 44  GLU D O     1 
ATOM   2331 C CB    . GLU B 1 44  ? 132.890 94.329  135.176 1.00 78.27  ? 44  GLU D CB    1 
ATOM   2332 C CG    . GLU B 1 44  ? 133.095 93.664  133.820 1.00 82.82  ? 44  GLU D CG    1 
ATOM   2333 C CD    . GLU B 1 44  ? 132.107 94.148  132.778 1.00 90.51  ? 44  GLU D CD    1 
ATOM   2334 O OE1   . GLU B 1 44  ? 132.195 95.327  132.376 1.00 88.61  ? 44  GLU D OE1   1 
ATOM   2335 O OE2   . GLU B 1 44  ? 131.244 93.349  132.358 1.00 97.25  ? 44  GLU D OE2   1 
ATOM   2336 N N     . ALA B 1 45  ? 135.164 96.460  135.374 1.00 76.07  ? 45  ALA D N     1 
ATOM   2337 C CA    . ALA B 1 45  ? 136.174 97.270  134.705 1.00 73.76  ? 45  ALA D CA    1 
ATOM   2338 C C     . ALA B 1 45  ? 137.536 97.087  135.355 1.00 74.40  ? 45  ALA D C     1 
ATOM   2339 O O     . ALA B 1 45  ? 138.537 96.847  134.668 1.00 78.41  ? 45  ALA D O     1 
ATOM   2340 C CB    . ALA B 1 45  ? 135.761 98.741  134.729 1.00 70.14  ? 45  ALA D CB    1 
ATOM   2341 N N     . CYS B 1 46  ? 137.598 97.200  136.683 1.00 71.30  ? 46  CYS D N     1 
ATOM   2342 C CA    . CYS B 1 46  ? 138.883 97.076  137.359 1.00 71.14  ? 46  CYS D CA    1 
ATOM   2343 C C     . CYS B 1 46  ? 139.472 95.688  137.157 1.00 76.02  ? 46  CYS D C     1 
ATOM   2344 O O     . CYS B 1 46  ? 140.670 95.550  136.887 1.00 73.97  ? 46  CYS D O     1 
ATOM   2345 C CB    . CYS B 1 46  ? 138.731 97.384  138.847 1.00 73.13  ? 46  CYS D CB    1 
ATOM   2346 S SG    . CYS B 1 46  ? 138.513 95.928  139.890 1.00 88.31  ? 46  CYS D SG    1 
ATOM   2347 N N     . GLY B 1 47  ? 138.646 94.644  137.271 1.00 78.93  ? 47  GLY D N     1 
ATOM   2348 C CA    . GLY B 1 47  ? 139.150 93.299  137.058 1.00 78.90  ? 47  GLY D CA    1 
ATOM   2349 C C     . GLY B 1 47  ? 139.686 93.102  135.654 1.00 82.34  ? 47  GLY D C     1 
ATOM   2350 O O     . GLY B 1 47  ? 140.799 92.611  135.466 1.00 82.60  ? 47  GLY D O     1 
ATOM   2351 N N     . HIS B 1 48  ? 138.912 93.512  134.647 1.00 82.28  ? 48  HIS D N     1 
ATOM   2352 C CA    . HIS B 1 48  ? 139.355 93.344  133.269 1.00 78.95  ? 48  HIS D CA    1 
ATOM   2353 C C     . HIS B 1 48  ? 140.652 94.097  133.013 1.00 82.33  ? 48  HIS D C     1 
ATOM   2354 O O     . HIS B 1 48  ? 141.568 93.572  132.371 1.00 86.41  ? 48  HIS D O     1 
ATOM   2355 C CB    . HIS B 1 48  ? 138.263 93.816  132.310 1.00 79.40  ? 48  HIS D CB    1 
ATOM   2356 C CG    . HIS B 1 48  ? 137.310 92.736  131.908 1.00 84.62  ? 48  HIS D CG    1 
ATOM   2357 N ND1   . HIS B 1 48  ? 137.521 91.928  130.812 1.00 89.75  ? 48  HIS D ND1   1 
ATOM   2358 C CD2   . HIS B 1 48  ? 136.149 92.320  132.465 1.00 85.84  ? 48  HIS D CD2   1 
ATOM   2359 C CE1   . HIS B 1 48  ? 136.525 91.067  130.706 1.00 93.41  ? 48  HIS D CE1   1 
ATOM   2360 N NE2   . HIS B 1 48  ? 135.679 91.284  131.697 1.00 92.94  ? 48  HIS D NE2   1 
ATOM   2361 N N     . VAL B 1 49  ? 140.753 95.329  133.513 1.00 80.35  ? 49  VAL D N     1 
ATOM   2362 C CA    . VAL B 1 49  ? 141.927 96.142  133.223 1.00 77.13  ? 49  VAL D CA    1 
ATOM   2363 C C     . VAL B 1 49  ? 143.156 95.608  133.952 1.00 78.17  ? 49  VAL D C     1 
ATOM   2364 O O     . VAL B 1 49  ? 144.262 95.601  133.397 1.00 74.01  ? 49  VAL D O     1 
ATOM   2365 C CB    . VAL B 1 49  ? 141.650 97.614  133.579 1.00 75.75  ? 49  VAL D CB    1 
ATOM   2366 C CG1   . VAL B 1 49  ? 142.915 98.438  133.450 1.00 75.80  ? 49  VAL D CG1   1 
ATOM   2367 C CG2   . VAL B 1 49  ? 140.561 98.176  132.685 1.00 74.63  ? 49  VAL D CG2   1 
ATOM   2368 N N     . PHE B 1 50  ? 142.995 95.149  135.196 1.00 82.30  ? 50  PHE D N     1 
ATOM   2369 C CA    . PHE B 1 50  ? 144.129 94.898  136.076 1.00 81.05  ? 50  PHE D CA    1 
ATOM   2370 C C     . PHE B 1 50  ? 144.381 93.426  136.379 1.00 81.57  ? 50  PHE D C     1 
ATOM   2371 O O     . PHE B 1 50  ? 145.264 93.127  137.190 1.00 85.77  ? 50  PHE D O     1 
ATOM   2372 C CB    . PHE B 1 50  ? 143.932 95.654  137.394 1.00 76.12  ? 50  PHE D CB    1 
ATOM   2373 C CG    . PHE B 1 50  ? 143.991 97.145  137.249 1.00 71.29  ? 50  PHE D CG    1 
ATOM   2374 C CD1   . PHE B 1 50  ? 145.202 97.790  137.084 1.00 72.37  ? 50  PHE D CD1   1 
ATOM   2375 C CD2   . PHE B 1 50  ? 142.835 97.901  137.274 1.00 68.25  ? 50  PHE D CD2   1 
ATOM   2376 C CE1   . PHE B 1 50  ? 145.259 99.159  136.950 1.00 66.66  ? 50  PHE D CE1   1 
ATOM   2377 C CE2   . PHE B 1 50  ? 142.887 99.271  137.142 1.00 65.19  ? 50  PHE D CE2   1 
ATOM   2378 C CZ    . PHE B 1 50  ? 144.100 99.899  136.978 1.00 65.75  ? 50  PHE D CZ    1 
ATOM   2379 N N     . GLY B 1 51  ? 143.651 92.501  135.763 1.00 79.86  ? 51  GLY D N     1 
ATOM   2380 C CA    . GLY B 1 51  ? 143.949 91.112  136.040 1.00 81.38  ? 51  GLY D CA    1 
ATOM   2381 C C     . GLY B 1 51  ? 143.711 90.773  137.499 1.00 86.13  ? 51  GLY D C     1 
ATOM   2382 O O     . GLY B 1 51  ? 142.868 91.364  138.182 1.00 85.74  ? 51  GLY D O     1 
ATOM   2383 N N     . SER B 1 52  ? 144.477 89.800  137.989 1.00 88.65  ? 52  SER D N     1 
ATOM   2384 C CA    . SER B 1 52  ? 144.408 89.400  139.387 1.00 85.35  ? 52  SER D CA    1 
ATOM   2385 C C     . SER B 1 52  ? 145.187 90.327  140.310 1.00 82.03  ? 52  SER D C     1 
ATOM   2386 O O     . SER B 1 52  ? 145.041 90.222  141.532 1.00 82.06  ? 52  SER D O     1 
ATOM   2387 C CB    . SER B 1 52  ? 144.932 87.970  139.545 1.00 87.87  ? 52  SER D CB    1 
ATOM   2388 O OG    . SER B 1 52  ? 146.306 87.893  139.206 1.00 90.43  ? 52  SER D OG    1 
ATOM   2389 N N     . SER B 1 53  ? 146.005 91.227  139.762 1.00 82.57  ? 53  SER D N     1 
ATOM   2390 C CA    . SER B 1 53  ? 146.817 92.106  140.595 1.00 84.95  ? 53  SER D CA    1 
ATOM   2391 C C     . SER B 1 53  ? 145.975 93.055  141.437 1.00 82.87  ? 53  SER D C     1 
ATOM   2392 O O     . SER B 1 53  ? 146.468 93.569  142.446 1.00 82.97  ? 53  SER D O     1 
ATOM   2393 C CB    . SER B 1 53  ? 147.781 92.909  139.721 1.00 87.12  ? 53  SER D CB    1 
ATOM   2394 O OG    . SER B 1 53  ? 147.151 93.335  138.525 1.00 88.27  ? 53  SER D OG    1 
ATOM   2395 N N     . PHE B 1 54  ? 144.726 93.296  141.053 1.00 79.28  ? 54  PHE D N     1 
ATOM   2396 C CA    . PHE B 1 54  ? 143.857 94.222  141.774 1.00 78.76  ? 54  PHE D CA    1 
ATOM   2397 C C     . PHE B 1 54  ? 143.466 93.604  143.109 1.00 82.97  ? 54  PHE D C     1 
ATOM   2398 O O     . PHE B 1 54  ? 142.659 92.674  143.166 1.00 82.05  ? 54  PHE D O     1 
ATOM   2399 C CB    . PHE B 1 54  ? 142.626 94.544  140.934 1.00 78.40  ? 54  PHE D CB    1 
ATOM   2400 C CG    . PHE B 1 54  ? 141.625 95.419  141.632 1.00 72.36  ? 54  PHE D CG    1 
ATOM   2401 C CD1   . PHE B 1 54  ? 141.731 96.795  141.575 1.00 67.47  ? 54  PHE D CD1   1 
ATOM   2402 C CD2   . PHE B 1 54  ? 140.573 94.864  142.336 1.00 71.02  ? 54  PHE D CD2   1 
ATOM   2403 C CE1   . PHE B 1 54  ? 140.809 97.600  142.208 1.00 64.15  ? 54  PHE D CE1   1 
ATOM   2404 C CE2   . PHE B 1 54  ? 139.651 95.666  142.974 1.00 69.72  ? 54  PHE D CE2   1 
ATOM   2405 C CZ    . PHE B 1 54  ? 139.770 97.035  142.909 1.00 65.40  ? 54  PHE D CZ    1 
ATOM   2406 N N     . ASN B 1 55  ? 144.037 94.124  144.194 1.00 84.23  ? 55  ASN D N     1 
ATOM   2407 C CA    . ASN B 1 55  ? 143.694 93.668  145.535 1.00 83.63  ? 55  ASN D CA    1 
ATOM   2408 C C     . ASN B 1 55  ? 142.431 94.383  146.000 1.00 79.55  ? 55  ASN D C     1 
ATOM   2409 O O     . ASN B 1 55  ? 142.391 95.616  146.050 1.00 73.85  ? 55  ASN D O     1 
ATOM   2410 C CB    . ASN B 1 55  ? 144.850 93.929  146.498 1.00 84.55  ? 55  ASN D CB    1 
ATOM   2411 C CG    . ASN B 1 55  ? 144.683 93.201  147.815 1.00 85.73  ? 55  ASN D CG    1 
ATOM   2412 O OD1   . ASN B 1 55  ? 143.751 92.417  147.989 1.00 79.97  ? 55  ASN D OD1   1 
ATOM   2413 N ND2   . ASN B 1 55  ? 145.592 93.452  148.750 1.00 86.70  ? 55  ASN D ND2   1 
ATOM   2414 N N     . ARG B 1 56  ? 141.404 93.608  146.346 1.00 77.69  ? 56  ARG D N     1 
ATOM   2415 C CA    . ARG B 1 56  ? 140.094 94.165  146.656 1.00 77.64  ? 56  ARG D CA    1 
ATOM   2416 C C     . ARG B 1 56  ? 139.960 94.637  148.098 1.00 79.82  ? 56  ARG D C     1 
ATOM   2417 O O     . ARG B 1 56  ? 138.922 95.209  148.446 1.00 78.58  ? 56  ARG D O     1 
ATOM   2418 C CB    . ARG B 1 56  ? 139.009 93.124  146.366 1.00 79.78  ? 56  ARG D CB    1 
ATOM   2419 C CG    . ARG B 1 56  ? 137.627 93.710  146.133 1.00 78.44  ? 56  ARG D CG    1 
ATOM   2420 C CD    . ARG B 1 56  ? 136.598 92.617  145.910 1.00 81.29  ? 56  ARG D CD    1 
ATOM   2421 N NE    . ARG B 1 56  ? 135.288 93.161  145.572 1.00 81.80  ? 56  ARG D NE    1 
ATOM   2422 C CZ    . ARG B 1 56  ? 134.242 92.429  145.215 1.00 86.02  ? 56  ARG D CZ    1 
ATOM   2423 N NH1   . ARG B 1 56  ? 134.313 91.109  145.142 1.00 85.85  ? 56  ARG D NH1   1 
ATOM   2424 N NH2   . ARG B 1 56  ? 133.096 93.035  144.922 1.00 86.73  ? 56  ARG D NH2   1 
ATOM   2425 N N     . GLU B 1 57  ? 140.968 94.418  148.943 1.00 81.22  ? 57  GLU D N     1 
ATOM   2426 C CA    . GLU B 1 57  ? 140.880 94.760  150.357 1.00 80.01  ? 57  GLU D CA    1 
ATOM   2427 C C     . GLU B 1 57  ? 141.925 95.782  150.788 1.00 77.13  ? 57  GLU D C     1 
ATOM   2428 O O     . GLU B 1 57  ? 142.203 95.896  151.988 1.00 75.93  ? 57  GLU D O     1 
ATOM   2429 C CB    . GLU B 1 57  ? 141.006 93.497  151.215 1.00 84.21  ? 57  GLU D CB    1 
ATOM   2430 C CG    . GLU B 1 57  ? 140.454 92.234  150.565 1.00 86.96  ? 57  GLU D CG    1 
ATOM   2431 C CD    . GLU B 1 57  ? 138.994 92.357  150.173 1.00 84.75  ? 57  GLU D CD    1 
ATOM   2432 O OE1   . GLU B 1 57  ? 138.382 93.407  150.458 1.00 80.41  ? 57  GLU D OE1   1 
ATOM   2433 O OE2   . GLU B 1 57  ? 138.456 91.401  149.576 1.00 81.29  ? 57  GLU D OE2   1 
ATOM   2434 N N     . ASP B 1 58  ? 142.511 96.524  149.854 1.00 75.65  ? 58  ASP D N     1 
ATOM   2435 C CA    . ASP B 1 58  ? 143.481 97.568  150.163 1.00 74.40  ? 58  ASP D CA    1 
ATOM   2436 C C     . ASP B 1 58  ? 142.942 98.899  149.660 1.00 67.77  ? 58  ASP D C     1 
ATOM   2437 O O     . ASP B 1 58  ? 142.645 99.044  148.469 1.00 68.89  ? 58  ASP D O     1 
ATOM   2438 C CB    . ASP B 1 58  ? 144.838 97.256  149.534 1.00 74.22  ? 58  ASP D CB    1 
ATOM   2439 C CG    . ASP B 1 58  ? 145.942 98.158  150.048 1.00 70.54  ? 58  ASP D CG    1 
ATOM   2440 O OD1   . ASP B 1 58  ? 145.628 99.190  150.675 1.00 68.74  ? 58  ASP D OD1   1 
ATOM   2441 O OD2   . ASP B 1 58  ? 147.126 97.835  149.821 1.00 70.51  ? 58  ASP D OD2   1 
ATOM   2442 N N     . ASN B 1 59  ? 142.818 99.869  150.567 1.00 62.83  ? 59  ASN D N     1 
ATOM   2443 C CA    . ASN B 1 59  ? 142.262 101.163 150.190 1.00 58.34  ? 59  ASN D CA    1 
ATOM   2444 C C     . ASN B 1 59  ? 143.144 101.867 149.167 1.00 61.99  ? 59  ASN D C     1 
ATOM   2445 O O     . ASN B 1 59  ? 142.639 102.455 148.205 1.00 67.00  ? 59  ASN D O     1 
ATOM   2446 C CB    . ASN B 1 59  ? 142.084 102.035 151.431 1.00 61.56  ? 59  ASN D CB    1 
ATOM   2447 C CG    . ASN B 1 59  ? 141.009 101.512 152.358 1.00 61.96  ? 59  ASN D CG    1 
ATOM   2448 O OD1   . ASN B 1 59  ? 139.981 101.005 151.911 1.00 63.84  ? 59  ASN D OD1   1 
ATOM   2449 N ND2   . ASN B 1 59  ? 141.238 101.634 153.660 1.00 58.89  ? 59  ASN D ND2   1 
ATOM   2450 N N     . SER B 1 60  ? 144.464 101.824 149.360 1.00 62.30  ? 60  SER D N     1 
ATOM   2451 C CA    . SER B 1 60  ? 145.365 102.494 148.427 1.00 63.11  ? 60  SER D CA    1 
ATOM   2452 C C     . SER B 1 60  ? 145.292 101.866 147.041 1.00 63.84  ? 60  SER D C     1 
ATOM   2453 O O     . SER B 1 60  ? 145.310 102.574 146.028 1.00 57.21  ? 60  SER D O     1 
ATOM   2454 C CB    . SER B 1 60  ? 146.795 102.449 148.961 1.00 60.52  ? 60  SER D CB    1 
ATOM   2455 O OG    . SER B 1 60  ? 146.821 102.706 150.353 1.00 66.70  ? 60  SER D OG    1 
ATOM   2456 N N     . VAL B 1 61  ? 145.215 100.535 146.975 1.00 69.64  ? 61  VAL D N     1 
ATOM   2457 C CA    . VAL B 1 61  ? 145.121 99.863  145.683 1.00 65.87  ? 61  VAL D CA    1 
ATOM   2458 C C     . VAL B 1 61  ? 143.835 100.257 144.972 1.00 60.76  ? 61  VAL D C     1 
ATOM   2459 O O     . VAL B 1 61  ? 143.834 100.537 143.768 1.00 65.91  ? 61  VAL D O     1 
ATOM   2460 C CB    . VAL B 1 61  ? 145.216 98.338  145.866 1.00 69.44  ? 61  VAL D CB    1 
ATOM   2461 C CG1   . VAL B 1 61  ? 144.829 97.625  144.583 1.00 70.02  ? 61  VAL D CG1   1 
ATOM   2462 C CG2   . VAL B 1 61  ? 146.618 97.944  146.300 1.00 72.34  ? 61  VAL D CG2   1 
ATOM   2463 N N     . ILE B 1 62  ? 142.716 100.272 145.698 1.00 55.06  ? 62  ILE D N     1 
ATOM   2464 C CA    . ILE B 1 62  ? 141.449 100.633 145.074 1.00 54.07  ? 62  ILE D CA    1 
ATOM   2465 C C     . ILE B 1 62  ? 141.478 102.084 144.621 1.00 49.12  ? 62  ILE D C     1 
ATOM   2466 O O     . ILE B 1 62  ? 140.936 102.426 143.567 1.00 51.48  ? 62  ILE D O     1 
ATOM   2467 C CB    . ILE B 1 62  ? 140.277 100.361 146.030 1.00 54.70  ? 62  ILE D CB    1 
ATOM   2468 C CG1   . ILE B 1 62  ? 140.138 98.860  146.285 1.00 60.20  ? 62  ILE D CG1   1 
ATOM   2469 C CG2   . ILE B 1 62  ? 138.987 100.900 145.441 1.00 52.31  ? 62  ILE D CG2   1 
ATOM   2470 C CD1   . ILE B 1 62  ? 139.224 98.511  147.442 1.00 65.01  ? 62  ILE D CD1   1 
ATOM   2471 N N     . SER B 1 63  ? 142.107 102.961 145.402 1.00 47.40  ? 63  SER D N     1 
ATOM   2472 C CA    . SER B 1 63  ? 142.213 104.357 144.993 1.00 49.80  ? 63  SER D CA    1 
ATOM   2473 C C     . SER B 1 63  ? 143.046 104.499 143.725 1.00 57.36  ? 63  SER D C     1 
ATOM   2474 O O     . SER B 1 63  ? 142.682 105.255 142.818 1.00 64.04  ? 63  SER D O     1 
ATOM   2475 C CB    . SER B 1 63  ? 142.811 105.186 146.127 1.00 53.61  ? 63  SER D CB    1 
ATOM   2476 O OG    . SER B 1 63  ? 142.198 104.856 147.360 1.00 55.85  ? 63  SER D OG    1 
ATOM   2477 N N     . ASP B 1 64  ? 144.170 103.780 143.641 1.00 63.01  ? 64  ASP D N     1 
ATOM   2478 C CA    . ASP B 1 64  ? 144.992 103.836 142.434 1.00 65.88  ? 64  ASP D CA    1 
ATOM   2479 C C     . ASP B 1 64  ? 144.236 103.301 141.224 1.00 55.45  ? 64  ASP D C     1 
ATOM   2480 O O     . ASP B 1 64  ? 144.290 103.891 140.137 1.00 51.70  ? 64  ASP D O     1 
ATOM   2481 C CB    . ASP B 1 64  ? 146.286 103.047 142.640 1.00 70.36  ? 64  ASP D CB    1 
ATOM   2482 C CG    . ASP B 1 64  ? 147.395 103.884 143.249 1.00 75.85  ? 64  ASP D CG    1 
ATOM   2483 O OD1   . ASP B 1 64  ? 147.421 105.110 143.015 1.00 68.65  ? 64  ASP D OD1   1 
ATOM   2484 O OD2   . ASP B 1 64  ? 148.247 103.312 143.960 1.00 77.79  ? 64  ASP D OD2   1 
ATOM   2485 N N     . ALA B 1 65  ? 143.527 102.183 141.389 1.00 52.30  ? 65  ALA D N     1 
ATOM   2486 C CA    . ALA B 1 65  ? 142.761 101.628 140.279 1.00 53.76  ? 65  ALA D CA    1 
ATOM   2487 C C     . ALA B 1 65  ? 141.655 102.581 139.843 1.00 54.17  ? 65  ALA D C     1 
ATOM   2488 O O     . ALA B 1 65  ? 141.410 102.752 138.643 1.00 61.99  ? 65  ALA D O     1 
ATOM   2489 C CB    . ALA B 1 65  ? 142.176 100.274 140.670 1.00 57.00  ? 65  ALA D CB    1 
ATOM   2490 N N     . ALA B 1 66  ? 140.968 103.202 140.802 1.00 48.24  ? 66  ALA D N     1 
ATOM   2491 C CA    . ALA B 1 66  ? 139.924 104.157 140.460 1.00 44.44  ? 66  ALA D CA    1 
ATOM   2492 C C     . ALA B 1 66  ? 140.500 105.355 139.727 1.00 48.11  ? 66  ALA D C     1 
ATOM   2493 O O     . ALA B 1 66  ? 139.906 105.844 138.762 1.00 59.40  ? 66  ALA D O     1 
ATOM   2494 C CB    . ALA B 1 66  ? 139.188 104.603 141.720 1.00 50.33  ? 66  ALA D CB    1 
ATOM   2495 N N     . ALA B 1 67  ? 141.658 105.848 140.168 1.00 47.10  ? 67  ALA D N     1 
ATOM   2496 C CA    . ALA B 1 67  ? 142.288 106.964 139.473 1.00 52.41  ? 67  ALA D CA    1 
ATOM   2497 C C     . ALA B 1 67  ? 142.655 106.581 138.046 1.00 55.54  ? 67  ALA D C     1 
ATOM   2498 O O     . ALA B 1 67  ? 142.444 107.362 137.110 1.00 56.66  ? 67  ALA D O     1 
ATOM   2499 C CB    . ALA B 1 67  ? 143.527 107.428 140.236 1.00 55.78  ? 67  ALA D CB    1 
ATOM   2500 N N     . PHE B 1 68  ? 143.208 105.381 137.858 1.00 58.83  ? 68  PHE D N     1 
ATOM   2501 C CA    . PHE B 1 68  ? 143.571 104.953 136.511 1.00 57.75  ? 68  PHE D CA    1 
ATOM   2502 C C     . PHE B 1 68  ? 142.343 104.828 135.620 1.00 51.89  ? 68  PHE D C     1 
ATOM   2503 O O     . PHE B 1 68  ? 142.367 105.253 134.461 1.00 55.39  ? 68  PHE D O     1 
ATOM   2504 C CB    . PHE B 1 68  ? 144.325 103.628 136.554 1.00 61.03  ? 68  PHE D CB    1 
ATOM   2505 C CG    . PHE B 1 68  ? 144.739 103.133 135.201 1.00 60.76  ? 68  PHE D CG    1 
ATOM   2506 C CD1   . PHE B 1 68  ? 145.886 103.613 134.595 1.00 66.78  ? 68  PHE D CD1   1 
ATOM   2507 C CD2   . PHE B 1 68  ? 143.976 102.198 134.529 1.00 61.92  ? 68  PHE D CD2   1 
ATOM   2508 C CE1   . PHE B 1 68  ? 146.266 103.162 133.347 1.00 70.76  ? 68  PHE D CE1   1 
ATOM   2509 C CE2   . PHE B 1 68  ? 144.352 101.745 133.281 1.00 67.67  ? 68  PHE D CE2   1 
ATOM   2510 C CZ    . PHE B 1 68  ? 145.497 102.229 132.691 1.00 70.95  ? 68  PHE D CZ    1 
ATOM   2511 N N     . LEU B 1 69  ? 141.263 104.239 136.136 1.00 49.02  ? 69  LEU D N     1 
ATOM   2512 C CA    . LEU B 1 69  ? 140.054 104.106 135.328 1.00 48.00  ? 69  LEU D CA    1 
ATOM   2513 C C     . LEU B 1 69  ? 139.449 105.468 135.015 1.00 48.76  ? 69  LEU D C     1 
ATOM   2514 O O     . LEU B 1 69  ? 138.906 105.675 133.924 1.00 55.46  ? 69  LEU D O     1 
ATOM   2515 C CB    . LEU B 1 69  ? 139.032 103.221 136.037 1.00 48.96  ? 69  LEU D CB    1 
ATOM   2516 C CG    . LEU B 1 69  ? 139.209 101.714 135.858 1.00 54.90  ? 69  LEU D CG    1 
ATOM   2517 C CD1   . LEU B 1 69  ? 138.185 100.963 136.684 1.00 62.99  ? 69  LEU D CD1   1 
ATOM   2518 C CD2   . LEU B 1 69  ? 139.100 101.321 134.398 1.00 59.15  ? 69  LEU D CD2   1 
ATOM   2519 N N     . PHE B 1 70  ? 139.520 106.406 135.960 1.00 47.50  ? 70  PHE D N     1 
ATOM   2520 C CA    . PHE B 1 70  ? 139.033 107.752 135.694 1.00 50.90  ? 70  PHE D CA    1 
ATOM   2521 C C     . PHE B 1 70  ? 139.856 108.424 134.606 1.00 59.01  ? 70  PHE D C     1 
ATOM   2522 O O     . PHE B 1 70  ? 139.308 109.115 133.740 1.00 62.58  ? 70  PHE D O     1 
ATOM   2523 C CB    . PHE B 1 70  ? 139.062 108.580 136.976 1.00 48.28  ? 70  PHE D CB    1 
ATOM   2524 C CG    . PHE B 1 70  ? 138.365 109.900 136.861 1.00 45.10  ? 70  PHE D CG    1 
ATOM   2525 C CD1   . PHE B 1 70  ? 137.063 109.970 136.406 1.00 46.75  ? 70  PHE D CD1   1 
ATOM   2526 C CD2   . PHE B 1 70  ? 139.005 111.068 137.222 1.00 50.88  ? 70  PHE D CD2   1 
ATOM   2527 C CE1   . PHE B 1 70  ? 136.419 111.178 136.303 1.00 48.99  ? 70  PHE D CE1   1 
ATOM   2528 C CE2   . PHE B 1 70  ? 138.362 112.280 137.121 1.00 60.55  ? 70  PHE D CE2   1 
ATOM   2529 C CZ    . PHE B 1 70  ? 137.066 112.333 136.661 1.00 56.64  ? 70  PHE D CZ    1 
ATOM   2530 N N     . LYS B 1 71  ? 141.177 108.237 134.633 1.00 57.88  ? 71  LYS D N     1 
ATOM   2531 C CA    . LYS B 1 71  ? 142.007 108.763 133.556 1.00 55.31  ? 71  LYS D CA    1 
ATOM   2532 C C     . LYS B 1 71  ? 141.634 108.127 132.224 1.00 59.53  ? 71  LYS D C     1 
ATOM   2533 O O     . LYS B 1 71  ? 141.525 108.816 131.204 1.00 65.44  ? 71  LYS D O     1 
ATOM   2534 C CB    . LYS B 1 71  ? 143.485 108.529 133.866 1.00 52.92  ? 71  LYS D CB    1 
ATOM   2535 C CG    . LYS B 1 71  ? 144.095 109.577 134.786 1.00 60.40  ? 71  LYS D CG    1 
ATOM   2536 C CD    . LYS B 1 71  ? 145.600 109.400 134.929 1.00 66.91  ? 71  LYS D CD    1 
ATOM   2537 C CE    . LYS B 1 71  ? 146.364 110.235 133.910 1.00 67.83  ? 71  LYS D CE    1 
ATOM   2538 N NZ    . LYS B 1 71  ? 147.840 110.170 134.109 1.00 67.37  ? 71  LYS D NZ    1 
ATOM   2539 N N     . MET B 1 72  ? 141.419 106.811 132.218 1.00 59.95  ? 72  MET D N     1 
ATOM   2540 C CA    . MET B 1 72  ? 141.080 106.115 130.981 1.00 54.73  ? 72  MET D CA    1 
ATOM   2541 C C     . MET B 1 72  ? 139.777 106.639 130.396 1.00 53.40  ? 72  MET D C     1 
ATOM   2542 O O     . MET B 1 72  ? 139.705 106.966 129.207 1.00 61.87  ? 72  MET D O     1 
ATOM   2543 C CB    . MET B 1 72  ? 140.982 104.613 131.242 1.00 55.54  ? 72  MET D CB    1 
ATOM   2544 C CG    . MET B 1 72  ? 140.599 103.783 130.032 1.00 58.82  ? 72  MET D CG    1 
ATOM   2545 S SD    . MET B 1 72  ? 140.195 102.085 130.469 1.00 64.70  ? 72  MET D SD    1 
ATOM   2546 C CE    . MET B 1 72  ? 141.746 101.553 131.178 1.00 64.94  ? 72  MET D CE    1 
ATOM   2547 N N     . HIS B 1 73  ? 138.734 106.730 131.219 1.00 54.32  ? 73  HIS D N     1 
ATOM   2548 C CA    . HIS B 1 73  ? 137.427 107.135 130.716 1.00 60.31  ? 73  HIS D CA    1 
ATOM   2549 C C     . HIS B 1 73  ? 137.349 108.624 130.408 1.00 58.13  ? 73  HIS D C     1 
ATOM   2550 O O     . HIS B 1 73  ? 136.372 109.057 129.790 1.00 60.06  ? 73  HIS D O     1 
ATOM   2551 C CB    . HIS B 1 73  ? 136.339 106.753 131.720 1.00 57.49  ? 73  HIS D CB    1 
ATOM   2552 C CG    . HIS B 1 73  ? 135.795 105.374 131.519 1.00 55.17  ? 73  HIS D CG    1 
ATOM   2553 N ND1   . HIS B 1 73  ? 134.449 105.118 131.375 1.00 56.02  ? 73  HIS D ND1   1 
ATOM   2554 C CD2   . HIS B 1 73  ? 136.417 104.175 131.430 1.00 60.32  ? 73  HIS D CD2   1 
ATOM   2555 C CE1   . HIS B 1 73  ? 134.265 103.821 131.209 1.00 60.08  ? 73  HIS D CE1   1 
ATOM   2556 N NE2   . HIS B 1 73  ? 135.443 103.226 131.240 1.00 62.10  ? 73  HIS D NE2   1 
ATOM   2557 N N     . THR B 1 74  ? 138.338 109.411 130.820 1.00 50.69  ? 74  THR D N     1 
ATOM   2558 C CA    . THR B 1 74  ? 138.396 110.827 130.491 1.00 56.91  ? 74  THR D CA    1 
ATOM   2559 C C     . THR B 1 74  ? 139.373 111.121 129.359 1.00 68.29  ? 74  THR D C     1 
ATOM   2560 O O     . THR B 1 74  ? 139.617 112.292 129.051 1.00 78.85  ? 74  THR D O     1 
ATOM   2561 C CB    . THR B 1 74  ? 138.774 111.641 131.728 1.00 59.67  ? 74  THR D CB    1 
ATOM   2562 O OG1   . THR B 1 74  ? 139.915 111.052 132.361 1.00 62.66  ? 74  THR D OG1   1 
ATOM   2563 C CG2   . THR B 1 74  ? 137.619 111.681 132.708 1.00 57.00  ? 74  THR D CG2   1 
ATOM   2564 N N     . HIS B 1 75  ? 139.935 110.089 128.732 1.00 66.92  ? 75  HIS D N     1 
ATOM   2565 C CA    . HIS B 1 75  ? 140.865 110.256 127.616 1.00 66.62  ? 75  HIS D CA    1 
ATOM   2566 C C     . HIS B 1 75  ? 142.074 111.096 128.009 1.00 67.86  ? 75  HIS D C     1 
ATOM   2567 O O     . HIS B 1 75  ? 142.648 111.803 127.179 1.00 75.73  ? 75  HIS D O     1 
ATOM   2568 C CB    . HIS B 1 75  ? 140.164 110.872 126.404 1.00 69.78  ? 75  HIS D CB    1 
ATOM   2569 C CG    . HIS B 1 75  ? 138.900 110.170 126.020 1.00 73.82  ? 75  HIS D CG    1 
ATOM   2570 N ND1   . HIS B 1 75  ? 137.654 110.631 126.386 1.00 77.53  ? 75  HIS D ND1   1 
ATOM   2571 C CD2   . HIS B 1 75  ? 138.690 109.039 125.307 1.00 75.63  ? 75  HIS D CD2   1 
ATOM   2572 C CE1   . HIS B 1 75  ? 136.730 109.814 125.912 1.00 79.46  ? 75  HIS D CE1   1 
ATOM   2573 N NE2   . HIS B 1 75  ? 137.332 108.841 125.254 1.00 78.80  ? 75  HIS D NE2   1 
ATOM   2574 N N     . SER B 1 76  ? 142.474 111.027 129.274 1.00 64.34  ? 76  SER D N     1 
ATOM   2575 C CA    . SER B 1 76  ? 143.649 111.737 129.753 1.00 66.07  ? 76  SER D CA    1 
ATOM   2576 C C     . SER B 1 76  ? 144.914 110.894 129.689 1.00 69.87  ? 76  SER D C     1 
ATOM   2577 O O     . SER B 1 76  ? 145.989 111.395 130.030 1.00 73.94  ? 76  SER D O     1 
ATOM   2578 C CB    . SER B 1 76  ? 143.426 112.216 131.189 1.00 68.49  ? 76  SER D CB    1 
ATOM   2579 O OG    . SER B 1 76  ? 142.249 113.000 131.284 1.00 68.53  ? 76  SER D OG    1 
ATOM   2580 N N     . LEU B 1 77  ? 144.817 109.637 129.267 1.00 70.14  ? 77  LEU D N     1 
ATOM   2581 C CA    . LEU B 1 77  ? 145.996 108.804 129.110 1.00 71.88  ? 77  LEU D CA    1 
ATOM   2582 C C     . LEU B 1 77  ? 146.663 109.076 127.764 1.00 82.81  ? 77  LEU D C     1 
ATOM   2583 O O     . LEU B 1 77  ? 146.118 109.755 126.890 1.00 87.44  ? 77  LEU D O     1 
ATOM   2584 C CB    . LEU B 1 77  ? 145.633 107.326 129.228 1.00 68.92  ? 77  LEU D CB    1 
ATOM   2585 C CG    . LEU B 1 77  ? 145.191 106.850 130.611 1.00 71.38  ? 77  LEU D CG    1 
ATOM   2586 C CD1   . LEU B 1 77  ? 144.676 105.423 130.535 1.00 71.51  ? 77  LEU D CD1   1 
ATOM   2587 C CD2   . LEU B 1 77  ? 146.330 106.958 131.610 1.00 70.86  ? 77  LEU D CD2   1 
ATOM   2588 N N     . ASP B 1 78  ? 147.866 108.535 127.604 1.00 90.61  ? 78  ASP D N     1 
ATOM   2589 C CA    . ASP B 1 78  ? 148.609 108.723 126.367 1.00 93.57  ? 78  ASP D CA    1 
ATOM   2590 C C     . ASP B 1 78  ? 147.974 107.928 125.233 1.00 94.36  ? 78  ASP D C     1 
ATOM   2591 O O     . ASP B 1 78  ? 147.525 106.794 125.420 1.00 95.98  ? 78  ASP D O     1 
ATOM   2592 C CB    . ASP B 1 78  ? 150.063 108.295 126.556 1.00 94.74  ? 78  ASP D CB    1 
ATOM   2593 C CG    . ASP B 1 78  ? 150.702 108.928 127.774 1.00 94.90  ? 78  ASP D CG    1 
ATOM   2594 O OD1   . ASP B 1 78  ? 149.960 109.324 128.695 1.00 97.64  ? 78  ASP D OD1   1 
ATOM   2595 O OD2   . ASP B 1 78  ? 151.946 109.030 127.810 1.00 92.77  ? 78  ASP D OD2   1 
ATOM   2596 N N     . GLY B 1 79  ? 147.944 108.530 124.048 1.00 94.49  ? 79  GLY D N     1 
ATOM   2597 C CA    . GLY B 1 79  ? 147.473 107.852 122.859 1.00 96.91  ? 79  GLY D CA    1 
ATOM   2598 C C     . GLY B 1 79  ? 145.979 107.886 122.631 1.00 93.36  ? 79  GLY D C     1 
ATOM   2599 O O     . GLY B 1 79  ? 145.495 107.187 121.733 1.00 97.59  ? 79  GLY D O     1 
ATOM   2600 N N     . GLN B 1 80  ? 145.233 108.670 123.403 1.00 87.15  ? 80  GLN D N     1 
ATOM   2601 C CA    . GLN B 1 80  ? 143.790 108.753 123.255 1.00 91.06  ? 80  GLN D CA    1 
ATOM   2602 C C     . GLN B 1 80  ? 143.414 110.010 122.471 1.00 89.67  ? 80  GLN D C     1 
ATOM   2603 O O     . GLN B 1 80  ? 144.266 110.799 122.061 1.00 91.22  ? 80  GLN D O     1 
ATOM   2604 C CB    . GLN B 1 80  ? 143.113 108.726 124.626 1.00 89.26  ? 80  GLN D CB    1 
ATOM   2605 C CG    . GLN B 1 80  ? 142.432 107.400 124.938 1.00 83.88  ? 80  GLN D CG    1 
ATOM   2606 C CD    . GLN B 1 80  ? 142.328 107.122 126.422 1.00 72.04  ? 80  GLN D CD    1 
ATOM   2607 O OE1   . GLN B 1 80  ? 143.019 107.738 127.232 1.00 68.92  ? 80  GLN D OE1   1 
ATOM   2608 N NE2   . GLN B 1 80  ? 141.461 106.186 126.787 1.00 69.85  ? 80  GLN D NE2   1 
ATOM   2609 N N     . GLU B 1 81  ? 142.112 110.191 122.263 1.00 92.08  ? 81  GLU D N     1 
ATOM   2610 C CA    . GLU B 1 81  ? 141.632 111.307 121.459 1.00 94.50  ? 81  GLU D CA    1 
ATOM   2611 C C     . GLU B 1 81  ? 142.055 112.634 122.074 1.00 93.02  ? 81  GLU D C     1 
ATOM   2612 O O     . GLU B 1 81  ? 142.186 112.764 123.294 1.00 90.13  ? 81  GLU D O     1 
ATOM   2613 C CB    . GLU B 1 81  ? 140.108 111.259 121.330 1.00 95.64  ? 81  GLU D CB    1 
ATOM   2614 C CG    . GLU B 1 81  ? 139.576 110.105 120.495 1.00 95.50  ? 81  GLU D CG    1 
ATOM   2615 C CD    . GLU B 1 81  ? 138.400 109.404 121.149 1.00 95.28  ? 81  GLU D CD    1 
ATOM   2616 O OE1   . GLU B 1 81  ? 138.504 109.038 122.338 1.00 92.42  ? 81  GLU D OE1   1 
ATOM   2617 O OE2   . GLU B 1 81  ? 137.363 109.225 120.475 1.00 96.43  ? 81  GLU D OE2   1 
ATOM   2618 N N     . ALA B 1 82  ? 142.274 113.623 121.213 1.00 92.70  ? 82  ALA D N     1 
ATOM   2619 C CA    . ALA B 1 82  ? 142.686 114.951 121.640 1.00 92.90  ? 82  ALA D CA    1 
ATOM   2620 C C     . ALA B 1 82  ? 141.468 115.856 121.766 1.00 94.89  ? 82  ALA D C     1 
ATOM   2621 O O     . ALA B 1 82  ? 140.648 115.936 120.847 1.00 94.76  ? 82  ALA D O     1 
ATOM   2622 C CB    . ALA B 1 82  ? 143.685 115.542 120.646 1.00 96.35  ? 82  ALA D CB    1 
ATOM   2623 N N     . LYS B 1 83  ? 141.357 116.537 122.906 1.00 97.78  ? 83  LYS D N     1 
ATOM   2624 C CA    . LYS B 1 83  ? 140.257 117.464 123.165 1.00 100.69 ? 83  LYS D CA    1 
ATOM   2625 C C     . LYS B 1 83  ? 140.640 118.811 122.567 1.00 103.76 ? 83  LYS D C     1 
ATOM   2626 O O     . LYS B 1 83  ? 141.454 119.545 123.131 1.00 108.06 ? 83  LYS D O     1 
ATOM   2627 C CB    . LYS B 1 83  ? 139.978 117.575 124.661 1.00 97.73  ? 83  LYS D CB    1 
ATOM   2628 C CG    . LYS B 1 83  ? 140.311 116.320 125.454 1.00 95.36  ? 83  LYS D CG    1 
ATOM   2629 C CD    . LYS B 1 83  ? 139.434 116.188 126.686 1.00 90.76  ? 83  LYS D CD    1 
ATOM   2630 C CE    . LYS B 1 83  ? 139.972 115.138 127.644 1.00 82.46  ? 83  LYS D CE    1 
ATOM   2631 N NZ    . LYS B 1 83  ? 139.549 115.398 129.046 1.00 73.57  ? 83  LYS D NZ    1 
ATOM   2632 N N     . VAL B 1 84  ? 140.052 119.138 121.415 1.00 100.43 ? 84  VAL D N     1 
ATOM   2633 C CA    . VAL B 1 84  ? 140.433 120.321 120.656 1.00 101.75 ? 84  VAL D CA    1 
ATOM   2634 C C     . VAL B 1 84  ? 139.242 121.182 120.269 1.00 104.72 ? 84  VAL D C     1 
ATOM   2635 O O     . VAL B 1 84  ? 139.397 122.109 119.473 1.00 106.54 ? 84  VAL D O     1 
ATOM   2636 C CB    . VAL B 1 84  ? 141.229 119.921 119.397 1.00 105.16 ? 84  VAL D CB    1 
ATOM   2637 C CG1   . VAL B 1 84  ? 141.881 121.140 118.767 1.00 107.64 ? 84  VAL D CG1   1 
ATOM   2638 C CG2   . VAL B 1 84  ? 142.264 118.856 119.745 1.00 103.08 ? 84  VAL D CG2   1 
ATOM   2639 N N     . LEU B 1 85  ? 138.052 120.912 120.809 1.00 105.18 ? 85  LEU D N     1 
ATOM   2640 C CA    . LEU B 1 85  ? 136.858 121.642 120.401 1.00 106.93 ? 85  LEU D CA    1 
ATOM   2641 C C     . LEU B 1 85  ? 137.062 123.147 120.534 1.00 105.16 ? 85  LEU D C     1 
ATOM   2642 O O     . LEU B 1 85  ? 137.004 123.888 119.547 1.00 104.13 ? 85  LEU D O     1 
ATOM   2643 C CB    . LEU B 1 85  ? 135.663 121.181 121.237 1.00 108.83 ? 85  LEU D CB    1 
ATOM   2644 C CG    . LEU B 1 85  ? 134.280 121.660 120.792 1.00 109.50 ? 85  LEU D CG    1 
ATOM   2645 C CD1   . LEU B 1 85  ? 133.937 121.115 119.417 1.00 105.44 ? 85  LEU D CD1   1 
ATOM   2646 C CD2   . LEU B 1 85  ? 133.222 121.256 121.804 1.00 106.00 ? 85  LEU D CD2   1 
ATOM   2647 N N     . ARG B 1 86  ? 137.310 123.615 121.757 1.00 103.08 ? 86  ARG D N     1 
ATOM   2648 C CA    . ARG B 1 86  ? 137.592 125.021 122.023 1.00 106.36 ? 86  ARG D CA    1 
ATOM   2649 C C     . ARG B 1 86  ? 138.931 125.171 122.735 1.00 109.30 ? 86  ARG D C     1 
ATOM   2650 O O     . ARG B 1 86  ? 139.147 126.131 123.480 1.00 109.72 ? 86  ARG D O     1 
ATOM   2651 C CB    . ARG B 1 86  ? 136.467 125.655 122.842 1.00 107.22 ? 86  ARG D CB    1 
ATOM   2652 C CG    . ARG B 1 86  ? 135.466 126.446 122.013 1.00 108.08 ? 86  ARG D CG    1 
ATOM   2653 C CD    . ARG B 1 86  ? 134.431 125.533 121.382 1.00 111.33 ? 86  ARG D CD    1 
ATOM   2654 N NE    . ARG B 1 86  ? 133.828 126.122 120.192 1.00 115.79 ? 86  ARG D NE    1 
ATOM   2655 C CZ    . ARG B 1 86  ? 132.890 125.538 119.459 1.00 116.73 ? 86  ARG D CZ    1 
ATOM   2656 N NH1   . ARG B 1 86  ? 132.413 124.343 119.768 1.00 112.53 ? 86  ARG D NH1   1 
ATOM   2657 N NH2   . ARG B 1 86  ? 132.417 126.170 118.388 1.00 120.35 ? 86  ARG D NH2   1 
ATOM   2658 N N     . ALA B 1 87  ? 139.840 124.228 122.510 1.00 109.16 ? 87  ALA D N     1 
ATOM   2659 C CA    . ALA B 1 87  ? 141.137 124.260 123.168 1.00 109.60 ? 87  ALA D CA    1 
ATOM   2660 C C     . ALA B 1 87  ? 141.966 125.443 122.685 1.00 110.42 ? 87  ALA D C     1 
ATOM   2661 O O     . ALA B 1 87  ? 141.984 125.767 121.494 1.00 104.44 ? 87  ALA D O     1 
ATOM   2662 C CB    . ALA B 1 87  ? 141.891 122.958 122.903 1.00 109.33 ? 87  ALA D CB    1 
ATOM   2663 N N     . SER B 1 88  ? 142.654 126.089 123.622 1.00 117.94 ? 88  SER D N     1 
ATOM   2664 C CA    . SER B 1 88  ? 143.621 127.111 123.261 1.00 120.61 ? 88  SER D CA    1 
ATOM   2665 C C     . SER B 1 88  ? 144.840 126.466 122.610 1.00 118.74 ? 88  SER D C     1 
ATOM   2666 O O     . SER B 1 88  ? 145.073 125.260 122.725 1.00 117.82 ? 88  SER D O     1 
ATOM   2667 C CB    . SER B 1 88  ? 144.046 127.914 124.492 1.00 117.23 ? 88  SER D CB    1 
ATOM   2668 O OG    . SER B 1 88  ? 142.968 128.677 125.005 1.00 114.74 ? 88  SER D OG    1 
ATOM   2669 N N     . GLU B 1 89  ? 145.626 127.292 121.918 1.00 118.92 ? 89  GLU D N     1 
ATOM   2670 C CA    . GLU B 1 89  ? 146.786 126.771 121.203 1.00 118.73 ? 89  GLU D CA    1 
ATOM   2671 C C     . GLU B 1 89  ? 147.691 125.973 122.132 1.00 117.62 ? 89  GLU D C     1 
ATOM   2672 O O     . GLU B 1 89  ? 148.252 124.945 121.736 1.00 116.30 ? 89  GLU D O     1 
ATOM   2673 C CB    . GLU B 1 89  ? 147.556 127.920 120.551 1.00 121.23 ? 89  GLU D CB    1 
ATOM   2674 C CG    . GLU B 1 89  ? 148.588 127.464 119.531 1.00 121.86 ? 89  GLU D CG    1 
ATOM   2675 C CD    . GLU B 1 89  ? 148.947 128.547 118.532 1.00 122.66 ? 89  GLU D CD    1 
ATOM   2676 O OE1   . GLU B 1 89  ? 148.343 129.639 118.588 1.00 123.14 ? 89  GLU D OE1   1 
ATOM   2677 O OE2   . GLU B 1 89  ? 149.834 128.304 117.688 1.00 122.16 ? 89  GLU D OE2   1 
ATOM   2678 N N     . LYS B 1 90  ? 147.837 126.424 123.379 1.00 115.74 ? 90  LYS D N     1 
ATOM   2679 C CA    . LYS B 1 90  ? 148.590 125.648 124.358 1.00 115.66 ? 90  LYS D CA    1 
ATOM   2680 C C     . LYS B 1 90  ? 147.883 124.336 124.677 1.00 113.12 ? 90  LYS D C     1 
ATOM   2681 O O     . LYS B 1 90  ? 148.516 123.273 124.719 1.00 110.07 ? 90  LYS D O     1 
ATOM   2682 C CB    . LYS B 1 90  ? 148.791 126.474 125.628 1.00 118.01 ? 90  LYS D CB    1 
ATOM   2683 C CG    . LYS B 1 90  ? 149.440 127.831 125.389 1.00 114.08 ? 90  LYS D CG    1 
ATOM   2684 C CD    . LYS B 1 90  ? 149.322 128.729 126.607 1.00 109.98 ? 90  LYS D CD    1 
ATOM   2685 C CE    . LYS B 1 90  ? 149.923 130.097 126.340 1.00 112.77 ? 90  LYS D CE    1 
ATOM   2686 N NZ    . LYS B 1 90  ? 149.814 131.002 127.515 1.00 112.33 ? 90  LYS D NZ    1 
ATOM   2687 N N     . LYS B 1 91  ? 146.568 124.392 124.898 1.00 112.46 ? 91  LYS D N     1 
ATOM   2688 C CA    . LYS B 1 91  ? 145.802 123.173 125.125 1.00 111.87 ? 91  LYS D CA    1 
ATOM   2689 C C     . LYS B 1 91  ? 145.851 122.267 123.902 1.00 114.61 ? 91  LYS D C     1 
ATOM   2690 O O     . LYS B 1 91  ? 145.974 121.042 124.030 1.00 111.78 ? 91  LYS D O     1 
ATOM   2691 C CB    . LYS B 1 91  ? 144.357 123.532 125.481 1.00 110.98 ? 91  LYS D CB    1 
ATOM   2692 C CG    . LYS B 1 91  ? 143.423 122.342 125.695 1.00 110.97 ? 91  LYS D CG    1 
ATOM   2693 C CD    . LYS B 1 91  ? 143.541 121.764 127.095 1.00 113.53 ? 91  LYS D CD    1 
ATOM   2694 C CE    . LYS B 1 91  ? 142.309 120.949 127.459 1.00 113.20 ? 91  LYS D CE    1 
ATOM   2695 N NZ    . LYS B 1 91  ? 141.098 121.796 127.651 1.00 112.20 ? 91  LYS D NZ    1 
ATOM   2696 N N     . ARG B 1 92  ? 145.747 122.852 122.705 1.00 116.98 ? 92  ARG D N     1 
ATOM   2697 C CA    . ARG B 1 92  ? 145.842 122.058 121.485 1.00 110.93 ? 92  ARG D CA    1 
ATOM   2698 C C     . ARG B 1 92  ? 147.182 121.345 121.404 1.00 109.63 ? 92  ARG D C     1 
ATOM   2699 O O     . ARG B 1 92  ? 147.241 120.154 121.080 1.00 105.32 ? 92  ARG D O     1 
ATOM   2700 C CB    . ARG B 1 92  ? 145.645 122.948 120.256 1.00 108.81 ? 92  ARG D CB    1 
ATOM   2701 C CG    . ARG B 1 92  ? 144.291 123.635 120.180 1.00 110.58 ? 92  ARG D CG    1 
ATOM   2702 C CD    . ARG B 1 92  ? 143.824 123.791 118.739 1.00 111.09 ? 92  ARG D CD    1 
ATOM   2703 N NE    . ARG B 1 92  ? 142.430 124.216 118.666 1.00 113.47 ? 92  ARG D NE    1 
ATOM   2704 C CZ    . ARG B 1 92  ? 141.644 124.046 117.611 1.00 107.59 ? 92  ARG D CZ    1 
ATOM   2705 N NH1   . ARG B 1 92  ? 142.081 123.463 116.507 1.00 103.88 ? 92  ARG D NH1   1 
ATOM   2706 N NH2   . ARG B 1 92  ? 140.382 124.465 117.669 1.00 107.66 ? 92  ARG D NH2   1 
ATOM   2707 N N     . GLU B 1 93  ? 148.271 122.059 121.696 1.00 111.61 ? 93  GLU D N     1 
ATOM   2708 C CA    . GLU B 1 93  ? 149.590 121.441 121.649 1.00 110.14 ? 93  GLU D CA    1 
ATOM   2709 C C     . GLU B 1 93  ? 149.711 120.326 122.677 1.00 104.84 ? 93  GLU D C     1 
ATOM   2710 O O     . GLU B 1 93  ? 150.258 119.258 122.383 1.00 100.04 ? 93  GLU D O     1 
ATOM   2711 C CB    . GLU B 1 93  ? 150.671 122.496 121.879 1.00 112.11 ? 93  GLU D CB    1 
ATOM   2712 C CG    . GLU B 1 93  ? 150.889 123.428 120.700 1.00 113.45 ? 93  GLU D CG    1 
ATOM   2713 C CD    . GLU B 1 93  ? 151.646 124.684 121.082 1.00 119.56 ? 93  GLU D CD    1 
ATOM   2714 O OE1   . GLU B 1 93  ? 151.730 124.988 122.291 1.00 117.32 ? 93  GLU D OE1   1 
ATOM   2715 O OE2   . GLU B 1 93  ? 152.166 125.364 120.174 1.00 125.42 ? 93  GLU D OE2   1 
ATOM   2716 N N     . ARG B 1 94  ? 149.211 120.556 123.892 1.00 104.43 ? 94  ARG D N     1 
ATOM   2717 C CA    . ARG B 1 94  ? 149.298 119.526 124.922 1.00 103.49 ? 94  ARG D CA    1 
ATOM   2718 C C     . ARG B 1 94  ? 148.539 118.274 124.504 1.00 102.77 ? 94  ARG D C     1 
ATOM   2719 O O     . ARG B 1 94  ? 149.053 117.153 124.611 1.00 103.38 ? 94  ARG D O     1 
ATOM   2720 C CB    . ARG B 1 94  ? 148.759 120.059 126.249 1.00 103.73 ? 94  ARG D CB    1 
ATOM   2721 C CG    . ARG B 1 94  ? 149.289 119.305 127.461 1.00 107.28 ? 94  ARG D CG    1 
ATOM   2722 C CD    . ARG B 1 94  ? 148.429 119.511 128.697 1.00 110.32 ? 94  ARG D CD    1 
ATOM   2723 N NE    . ARG B 1 94  ? 147.625 120.725 128.627 1.00 109.72 ? 94  ARG D NE    1 
ATOM   2724 C CZ    . ARG B 1 94  ? 146.480 120.905 129.272 1.00 109.79 ? 94  ARG D CZ    1 
ATOM   2725 N NH1   . ARG B 1 94  ? 145.968 119.966 130.052 1.00 110.91 ? 94  ARG D NH1   1 
ATOM   2726 N NH2   . ARG B 1 94  ? 145.834 122.059 129.134 1.00 108.22 ? 94  ARG D NH2   1 
ATOM   2727 N N     . GLU B 1 95  ? 147.310 118.446 124.016 1.00 103.01 ? 95  GLU D N     1 
ATOM   2728 C CA    . GLU B 1 95  ? 146.509 117.294 123.619 1.00 101.03 ? 95  GLU D CA    1 
ATOM   2729 C C     . GLU B 1 95  ? 147.131 116.574 122.427 1.00 102.01 ? 95  GLU D C     1 
ATOM   2730 O O     . GLU B 1 95  ? 147.119 115.340 122.368 1.00 96.15  ? 95  GLU D O     1 
ATOM   2731 C CB    . GLU B 1 95  ? 145.082 117.736 123.299 1.00 104.43 ? 95  GLU D CB    1 
ATOM   2732 C CG    . GLU B 1 95  ? 144.307 118.280 124.493 1.00 104.14 ? 95  GLU D CG    1 
ATOM   2733 C CD    . GLU B 1 95  ? 144.100 117.246 125.584 1.00 97.72  ? 95  GLU D CD    1 
ATOM   2734 O OE1   . GLU B 1 95  ? 143.566 116.158 125.280 1.00 95.90  ? 95  GLU D OE1   1 
ATOM   2735 O OE2   . GLU B 1 95  ? 144.461 117.522 126.745 1.00 93.86  ? 95  GLU D OE2   1 
ATOM   2736 N N     . ASN B 1 96  ? 147.672 117.325 121.464 1.00 106.06 ? 96  ASN D N     1 
ATOM   2737 C CA    . ASN B 1 96  ? 148.312 116.701 120.311 1.00 103.07 ? 96  ASN D CA    1 
ATOM   2738 C C     . ASN B 1 96  ? 149.550 115.918 120.727 1.00 101.31 ? 96  ASN D C     1 
ATOM   2739 O O     . ASN B 1 96  ? 149.800 114.821 120.214 1.00 97.85  ? 96  ASN D O     1 
ATOM   2740 C CB    . ASN B 1 96  ? 148.674 117.763 119.274 1.00 102.29 ? 96  ASN D CB    1 
ATOM   2741 C CG    . ASN B 1 96  ? 147.489 118.173 118.422 1.00 99.29  ? 96  ASN D CG    1 
ATOM   2742 O OD1   . ASN B 1 96  ? 147.376 117.775 117.263 1.00 101.90 ? 96  ASN D OD1   1 
ATOM   2743 N ND2   . ASN B 1 96  ? 146.598 118.977 118.993 1.00 97.03  ? 96  ASN D ND2   1 
ATOM   2744 N N     . ALA B 1 97  ? 150.344 116.470 121.646 1.00 100.88 ? 97  ALA D N     1 
ATOM   2745 C CA    . ALA B 1 97  ? 151.503 115.743 122.147 1.00 100.73 ? 97  ALA D CA    1 
ATOM   2746 C C     . ALA B 1 97  ? 151.074 114.474 122.869 1.00 101.44 ? 97  ALA D C     1 
ATOM   2747 O O     . ALA B 1 97  ? 151.711 113.423 122.727 1.00 102.53 ? 97  ALA D O     1 
ATOM   2748 C CB    . ALA B 1 97  ? 152.324 116.641 123.072 1.00 101.30 ? 97  ALA D CB    1 
ATOM   2749 N N     . LYS B 1 98  ? 149.994 114.551 123.647 1.00 101.16 ? 98  LYS D N     1 
ATOM   2750 C CA    . LYS B 1 98  ? 149.473 113.353 124.297 1.00 101.41 ? 98  LYS D CA    1 
ATOM   2751 C C     . LYS B 1 98  ? 149.071 112.310 123.262 1.00 100.60 ? 98  LYS D C     1 
ATOM   2752 O O     . LYS B 1 98  ? 149.387 111.123 123.400 1.00 102.14 ? 98  LYS D O     1 
ATOM   2753 C CB    . LYS B 1 98  ? 148.283 113.719 125.186 1.00 98.54  ? 98  LYS D CB    1 
ATOM   2754 C CG    . LYS B 1 98  ? 147.580 112.525 125.819 1.00 91.86  ? 98  LYS D CG    1 
ATOM   2755 C CD    . LYS B 1 98  ? 146.433 112.964 126.712 1.00 88.48  ? 98  LYS D CD    1 
ATOM   2756 C CE    . LYS B 1 98  ? 145.189 113.295 125.903 1.00 92.15  ? 98  LYS D CE    1 
ATOM   2757 N NZ    . LYS B 1 98  ? 144.333 114.307 126.580 1.00 90.69  ? 98  LYS D NZ    1 
ATOM   2758 N N     . LYS B 1 99  ? 148.374 112.741 122.211 1.00 99.08  ? 99  LYS D N     1 
ATOM   2759 C CA    . LYS B 1 99  ? 147.932 111.809 121.180 1.00 102.31 ? 99  LYS D CA    1 
ATOM   2760 C C     . LYS B 1 99  ? 149.121 111.152 120.492 1.00 99.26  ? 99  LYS D C     1 
ATOM   2761 O O     . LYS B 1 99  ? 149.138 109.935 120.277 1.00 97.90  ? 99  LYS D O     1 
ATOM   2762 C CB    . LYS B 1 99  ? 147.056 112.542 120.163 1.00 103.72 ? 99  LYS D CB    1 
ATOM   2763 C CG    . LYS B 1 99  ? 146.725 111.740 118.911 1.00 104.74 ? 99  LYS D CG    1 
ATOM   2764 C CD    . LYS B 1 99  ? 146.118 110.387 119.245 1.00 100.57 ? 99  LYS D CD    1 
ATOM   2765 C CE    . LYS B 1 99  ? 145.466 109.753 118.026 1.00 100.46 ? 99  LYS D CE    1 
ATOM   2766 N NZ    . LYS B 1 99  ? 144.341 110.572 117.492 1.00 100.99 ? 99  LYS D NZ    1 
ATOM   2767 N N     . SER B 1 100 ? 150.132 111.947 120.141 1.00 98.20  ? 100 SER D N     1 
ATOM   2768 C CA    . SER B 1 100 ? 151.301 111.393 119.469 1.00 101.72 ? 100 SER D CA    1 
ATOM   2769 C C     . SER B 1 100 ? 152.086 110.466 120.387 1.00 106.48 ? 100 SER D C     1 
ATOM   2770 O O     . SER B 1 100 ? 152.711 109.510 119.914 1.00 110.75 ? 100 SER D O     1 
ATOM   2771 C CB    . SER B 1 100 ? 152.195 112.523 118.962 1.00 100.03 ? 100 SER D CB    1 
ATOM   2772 O OG    . SER B 1 100 ? 151.424 113.549 118.362 1.00 95.92  ? 100 SER D OG    1 
ATOM   2773 N N     . ARG B 1 101 ? 152.064 110.726 121.692 1.00 105.59 ? 101 ARG D N     1 
ATOM   2774 C CA    . ARG B 1 101 ? 152.792 109.887 122.631 1.00 104.33 ? 101 ARG D CA    1 
ATOM   2775 C C     . ARG B 1 101 ? 152.234 108.470 122.623 1.00 107.42 ? 101 ARG D C     1 
ATOM   2776 O O     . ARG B 1 101 ? 151.029 108.258 122.462 1.00 105.97 ? 101 ARG D O     1 
ATOM   2777 C CB    . ARG B 1 101 ? 152.709 110.475 124.039 1.00 102.69 ? 101 ARG D CB    1 
ATOM   2778 C CG    . ARG B 1 101 ? 153.757 111.532 124.329 1.00 104.36 ? 101 ARG D CG    1 
ATOM   2779 C CD    . ARG B 1 101 ? 153.502 112.210 125.662 1.00 101.81 ? 101 ARG D CD    1 
ATOM   2780 N NE    . ARG B 1 101 ? 152.822 113.489 125.502 1.00 98.63  ? 101 ARG D NE    1 
ATOM   2781 C CZ    . ARG B 1 101 ? 152.180 114.124 126.474 1.00 100.94 ? 101 ARG D CZ    1 
ATOM   2782 N NH1   . ARG B 1 101 ? 152.109 113.627 127.697 1.00 103.91 ? 101 ARG D NH1   1 
ATOM   2783 N NH2   . ARG B 1 101 ? 151.597 115.290 126.211 1.00 102.23 ? 101 ARG D NH2   1 
ATOM   2784 N N     . LYS B 1 102 ? 153.122 107.496 122.795 1.00 114.07 ? 102 LYS D N     1 
ATOM   2785 C CA    . LYS B 1 102 ? 152.707 106.102 122.821 1.00 114.02 ? 102 LYS D CA    1 
ATOM   2786 C C     . LYS B 1 102 ? 151.825 105.831 124.032 1.00 110.37 ? 102 LYS D C     1 
ATOM   2787 O O     . LYS B 1 102 ? 152.075 106.336 125.130 1.00 108.99 ? 102 LYS D O     1 
ATOM   2788 C CB    . LYS B 1 102 ? 153.929 105.185 122.851 1.00 115.39 ? 102 LYS D CB    1 
ATOM   2789 C CG    . LYS B 1 102 ? 153.594 103.706 122.790 1.00 118.33 ? 102 LYS D CG    1 
ATOM   2790 C CD    . LYS B 1 102 ? 154.847 102.859 122.659 1.00 123.52 ? 102 LYS D CD    1 
ATOM   2791 C CE    . LYS B 1 102 ? 154.505 101.388 122.494 1.00 128.73 ? 102 LYS D CE    1 
ATOM   2792 N NZ    . LYS B 1 102 ? 155.717 100.556 122.267 1.00 132.72 ? 102 LYS D NZ    1 
ATOM   2793 N N     . ALA B 1 103 ? 150.786 105.026 123.827 1.00 105.00 ? 103 ALA D N     1 
ATOM   2794 C CA    . ALA B 1 103 ? 149.910 104.650 124.918 1.00 101.75 ? 103 ALA D CA    1 
ATOM   2795 C C     . ALA B 1 103 ? 150.640 103.706 125.871 1.00 105.13 ? 103 ALA D C     1 
ATOM   2796 O O     . ALA B 1 103 ? 151.630 103.074 125.494 1.00 108.67 ? 103 ALA D O     1 
ATOM   2797 C CB    . ALA B 1 103 ? 148.646 103.984 124.383 1.00 96.64  ? 103 ALA D CB    1 
ATOM   2798 N N     . PRO B 1 104 ? 150.176 103.599 127.115 1.00 100.90 ? 104 PRO D N     1 
ATOM   2799 C CA    . PRO B 1 104 ? 150.855 102.717 128.071 1.00 98.03  ? 104 PRO D CA    1 
ATOM   2800 C C     . PRO B 1 104 ? 150.915 101.288 127.552 1.00 103.21 ? 104 PRO D C     1 
ATOM   2801 O O     . PRO B 1 104 ? 149.962 100.782 126.958 1.00 103.97 ? 104 PRO D O     1 
ATOM   2802 C CB    . PRO B 1 104 ? 149.990 102.823 129.331 1.00 95.06  ? 104 PRO D CB    1 
ATOM   2803 C CG    . PRO B 1 104 ? 149.244 104.099 129.187 1.00 95.67  ? 104 PRO D CG    1 
ATOM   2804 C CD    . PRO B 1 104 ? 149.038 104.308 127.723 1.00 97.86  ? 104 PRO D CD    1 
ATOM   2805 N N     . GLU B 1 105 ? 152.050 100.638 127.785 1.00 105.66 ? 105 GLU D N     1 
ATOM   2806 C CA    . GLU B 1 105 ? 152.269 99.283  127.306 1.00 108.93 ? 105 GLU D CA    1 
ATOM   2807 C C     . GLU B 1 105 ? 151.804 98.268  128.343 1.00 101.53 ? 105 GLU D C     1 
ATOM   2808 O O     . GLU B 1 105 ? 151.790 98.540  129.546 1.00 99.36  ? 105 GLU D O     1 
ATOM   2809 C CB    . GLU B 1 105 ? 153.747 99.057  126.979 1.00 111.09 ? 105 GLU D CB    1 
ATOM   2810 C CG    . GLU B 1 105 ? 154.671 99.109  128.185 1.00 108.40 ? 105 GLU D CG    1 
ATOM   2811 C CD    . GLU B 1 105 ? 156.110 99.405  127.805 1.00 108.77 ? 105 GLU D CD    1 
ATOM   2812 O OE1   . GLU B 1 105 ? 156.596 98.826  126.810 1.00 107.28 ? 105 GLU D OE1   1 
ATOM   2813 O OE2   . GLU B 1 105 ? 156.756 100.215 128.502 1.00 105.77 ? 105 GLU D OE2   1 
ATOM   2814 N N     . ALA B 1 106 ? 151.421 97.088  127.860 1.00 94.15  ? 106 ALA D N     1 
ATOM   2815 C CA    . ALA B 1 106 ? 150.929 96.044  128.747 1.00 91.12  ? 106 ALA D CA    1 
ATOM   2816 C C     . ALA B 1 106 ? 152.000 95.652  129.755 1.00 91.75  ? 106 ALA D C     1 
ATOM   2817 O O     . ALA B 1 106 ? 153.191 95.602  129.437 1.00 92.18  ? 106 ALA D O     1 
ATOM   2818 C CB    . ALA B 1 106 ? 150.496 94.822  127.938 1.00 89.84  ? 106 ALA D CB    1 
ATOM   2819 N N     . GLY B 1 107 ? 151.568 95.369  130.982 1.00 92.13  ? 107 GLY D N     1 
ATOM   2820 C CA    . GLY B 1 107 ? 152.475 95.042  132.059 1.00 92.54  ? 107 GLY D CA    1 
ATOM   2821 C C     . GLY B 1 107 ? 153.047 96.234  132.792 1.00 93.53  ? 107 GLY D C     1 
ATOM   2822 O O     . GLY B 1 107 ? 153.856 96.044  133.708 1.00 94.93  ? 107 GLY D O     1 
ATOM   2823 N N     . MET B 1 108 ? 152.656 97.451  132.422 1.00 93.50  ? 108 MET D N     1 
ATOM   2824 C CA    . MET B 1 108 ? 153.177 98.635  133.089 1.00 91.63  ? 108 MET D CA    1 
ATOM   2825 C C     . MET B 1 108 ? 152.733 98.653  134.545 1.00 89.26  ? 108 MET D C     1 
ATOM   2826 O O     . MET B 1 108 ? 151.632 98.210  134.884 1.00 85.75  ? 108 MET D O     1 
ATOM   2827 C CB    . MET B 1 108 ? 152.702 99.899  132.367 1.00 94.47  ? 108 MET D CB    1 
ATOM   2828 C CG    . MET B 1 108 ? 153.070 101.211 133.051 1.00 93.59  ? 108 MET D CG    1 
ATOM   2829 S SD    . MET B 1 108 ? 152.116 102.605 132.423 1.00 108.63 ? 108 MET D SD    1 
ATOM   2830 C CE    . MET B 1 108 ? 150.518 102.302 133.175 1.00 89.41  ? 108 MET D CE    1 
ATOM   2831 N N     . ARG B 1 109 ? 153.602 99.167  135.409 1.00 93.52  ? 109 ARG D N     1 
ATOM   2832 C CA    . ARG B 1 109 ? 153.305 99.242  136.831 1.00 95.74  ? 109 ARG D CA    1 
ATOM   2833 C C     . ARG B 1 109 ? 152.444 100.465 137.121 1.00 92.50  ? 109 ARG D C     1 
ATOM   2834 O O     . ARG B 1 109 ? 152.850 101.599 136.852 1.00 92.81  ? 109 ARG D O     1 
ATOM   2835 C CB    . ARG B 1 109 ? 154.599 99.302  137.642 1.00 95.05  ? 109 ARG D CB    1 
ATOM   2836 C CG    . ARG B 1 109 ? 155.013 97.976  138.255 1.00 92.55  ? 109 ARG D CG    1 
ATOM   2837 C CD    . ARG B 1 109 ? 156.308 98.116  139.031 1.00 93.70  ? 109 ARG D CD    1 
ATOM   2838 N NE    . ARG B 1 109 ? 156.742 96.849  139.606 1.00 99.45  ? 109 ARG D NE    1 
ATOM   2839 C CZ    . ARG B 1 109 ? 157.893 96.667  140.239 1.00 99.36  ? 109 ARG D CZ    1 
ATOM   2840 N NH1   . ARG B 1 109 ? 158.761 97.654  140.395 1.00 99.44  ? 109 ARG D NH1   1 
ATOM   2841 N NH2   . ARG B 1 109 ? 158.181 95.465  140.730 1.00 98.69  ? 109 ARG D NH2   1 
ATOM   2842 N N     . VAL B 1 110 ? 151.260 100.232 137.678 1.00 88.01  ? 110 VAL D N     1 
ATOM   2843 C CA    . VAL B 1 110 ? 150.341 101.295 138.067 1.00 82.06  ? 110 VAL D CA    1 
ATOM   2844 C C     . VAL B 1 110 ? 150.470 101.483 139.569 1.00 86.84  ? 110 VAL D C     1 
ATOM   2845 O O     . VAL B 1 110 ? 150.227 100.548 140.342 1.00 87.51  ? 110 VAL D O     1 
ATOM   2846 C CB    . VAL B 1 110 ? 148.892 100.967 137.679 1.00 81.36  ? 110 VAL D CB    1 
ATOM   2847 C CG1   . VAL B 1 110 ? 147.987 102.153 137.968 1.00 78.60  ? 110 VAL D CG1   1 
ATOM   2848 C CG2   . VAL B 1 110 ? 148.807 100.570 136.216 1.00 85.78  ? 110 VAL D CG2   1 
ATOM   2849 N N     . GLY B 1 111 ? 150.852 102.687 139.984 1.00 92.82  ? 111 GLY D N     1 
ATOM   2850 C CA    . GLY B 1 111 ? 151.038 102.972 141.392 1.00 92.85  ? 111 GLY D CA    1 
ATOM   2851 C C     . GLY B 1 111 ? 152.104 102.103 142.024 1.00 89.03  ? 111 GLY D C     1 
ATOM   2852 O O     . GLY B 1 111 ? 153.289 102.232 141.701 1.00 81.00  ? 111 GLY D O     1 
ATOM   2853 N N     . ARG B 1 112 ? 151.698 101.214 142.928 1.00 89.93  ? 112 ARG D N     1 
ATOM   2854 C CA    . ARG B 1 112 ? 152.621 100.324 143.621 1.00 91.42  ? 112 ARG D CA    1 
ATOM   2855 C C     . ARG B 1 112 ? 152.366 98.857  143.317 1.00 91.62  ? 112 ARG D C     1 
ATOM   2856 O O     . ARG B 1 112 ? 153.294 98.143  142.920 1.00 91.06  ? 112 ARG D O     1 
ATOM   2857 C CB    . ARG B 1 112 ? 152.532 100.563 145.138 1.00 88.84  ? 112 ARG D CB    1 
ATOM   2858 C CG    . ARG B 1 112 ? 153.432 99.663  145.982 1.00 85.11  ? 112 ARG D CG    1 
ATOM   2859 C CD    . ARG B 1 112 ? 154.892 99.732  145.552 1.00 88.41  ? 112 ARG D CD    1 
ATOM   2860 N NE    . ARG B 1 112 ? 155.341 98.505  144.905 1.00 93.29  ? 112 ARG D NE    1 
ATOM   2861 C CZ    . ARG B 1 112 ? 156.597 98.257  144.561 1.00 91.37  ? 112 ARG D CZ    1 
ATOM   2862 N NH1   . ARG B 1 112 ? 157.560 99.140  144.772 1.00 88.53  ? 112 ARG D NH1   1 
ATOM   2863 N NH2   . ARG B 1 112 ? 156.896 97.095  143.987 1.00 90.49  ? 112 ARG D NH2   1 
ATOM   2864 N N     . SER B 1 113 ? 151.132 98.386  143.484 1.00 92.07  ? 113 SER D N     1 
ATOM   2865 C CA    . SER B 1 113 ? 150.809 96.968  143.378 1.00 94.23  ? 113 SER D CA    1 
ATOM   2866 C C     . SER B 1 113 ? 149.677 96.737  142.388 1.00 89.36  ? 113 SER D C     1 
ATOM   2867 O O     . SER B 1 113 ? 148.801 95.895  142.604 1.00 86.77  ? 113 SER D O     1 
ATOM   2868 C CB    . SER B 1 113 ? 150.446 96.392  144.744 1.00 94.13  ? 113 SER D CB    1 
ATOM   2869 O OG    . SER B 1 113 ? 149.045 96.403  144.945 1.00 88.72  ? 113 SER D OG    1 
ATOM   2870 N N     . LEU B 1 114 ? 149.680 97.480  141.283 1.00 85.57  ? 114 LEU D N     1 
ATOM   2871 C CA    . LEU B 1 114 ? 148.708 97.299  140.211 1.00 86.86  ? 114 LEU D CA    1 
ATOM   2872 C C     . LEU B 1 114 ? 149.461 97.229  138.892 1.00 89.60  ? 114 LEU D C     1 
ATOM   2873 O O     . LEU B 1 114 ? 150.230 98.139  138.567 1.00 93.68  ? 114 LEU D O     1 
ATOM   2874 C CB    . LEU B 1 114 ? 147.686 98.439  140.186 1.00 83.87  ? 114 LEU D CB    1 
ATOM   2875 C CG    . LEU B 1 114 ? 146.578 98.379  141.238 1.00 79.67  ? 114 LEU D CG    1 
ATOM   2876 C CD1   . LEU B 1 114 ? 145.776 99.667  141.234 1.00 69.35  ? 114 LEU D CD1   1 
ATOM   2877 C CD2   . LEU B 1 114 ? 145.667 97.188  141.004 1.00 75.49  ? 114 LEU D CD2   1 
ATOM   2878 N N     . ILE B 1 115 ? 149.242 96.154  138.138 1.00 86.69  ? 115 ILE D N     1 
ATOM   2879 C CA    . ILE B 1 115 ? 149.926 95.925  136.872 1.00 87.81  ? 115 ILE D CA    1 
ATOM   2880 C C     . ILE B 1 115 ? 148.878 95.720  135.789 1.00 87.73  ? 115 ILE D C     1 
ATOM   2881 O O     . ILE B 1 115 ? 147.971 94.895  135.945 1.00 82.46  ? 115 ILE D O     1 
ATOM   2882 C CB    . ILE B 1 115 ? 150.873 94.714  136.941 1.00 91.67  ? 115 ILE D CB    1 
ATOM   2883 C CG1   . ILE B 1 115 ? 152.004 94.981  137.939 1.00 91.30  ? 115 ILE D CG1   1 
ATOM   2884 C CG2   . ILE B 1 115 ? 151.434 94.407  135.559 1.00 92.72  ? 115 ILE D CG2   1 
ATOM   2885 C CD1   . ILE B 1 115 ? 152.791 93.742  138.325 1.00 88.85  ? 115 ILE D CD1   1 
ATOM   2886 N N     . LEU B 1 116 ? 149.011 96.461  134.692 1.00 90.91  ? 116 LEU D N     1 
ATOM   2887 C CA    . LEU B 1 116 ? 148.075 96.344  133.585 1.00 89.59  ? 116 LEU D CA    1 
ATOM   2888 C C     . LEU B 1 116 ? 148.225 94.999  132.888 1.00 89.19  ? 116 LEU D C     1 
ATOM   2889 O O     . LEU B 1 116 ? 149.320 94.437  132.798 1.00 88.79  ? 116 LEU D O     1 
ATOM   2890 C CB    . LEU B 1 116 ? 148.301 97.467  132.576 1.00 86.74  ? 116 LEU D CB    1 
ATOM   2891 C CG    . LEU B 1 116 ? 147.515 98.757  132.792 1.00 85.29  ? 116 LEU D CG    1 
ATOM   2892 C CD1   . LEU B 1 116 ? 147.966 99.815  131.800 1.00 89.66  ? 116 LEU D CD1   1 
ATOM   2893 C CD2   . LEU B 1 116 ? 146.029 98.500  132.660 1.00 80.24  ? 116 LEU D CD2   1 
ATOM   2894 N N     . THR B 1 117 ? 147.108 94.486  132.387 1.00 90.86  ? 117 THR D N     1 
ATOM   2895 C CA    . THR B 1 117 ? 147.110 93.269  131.595 1.00 90.43  ? 117 THR D CA    1 
ATOM   2896 C C     . THR B 1 117 ? 147.179 93.606  130.108 1.00 90.93  ? 117 THR D C     1 
ATOM   2897 O O     . THR B 1 117 ? 146.984 94.749  129.689 1.00 90.38  ? 117 THR D O     1 
ATOM   2898 C CB    . THR B 1 117 ? 145.867 92.431  131.893 1.00 87.30  ? 117 THR D CB    1 
ATOM   2899 O OG1   . THR B 1 117 ? 144.734 92.988  131.214 1.00 86.22  ? 117 THR D OG1   1 
ATOM   2900 C CG2   . THR B 1 117 ? 145.592 92.397  133.385 1.00 86.44  ? 117 THR D CG2   1 
ATOM   2901 N N     . SER B 1 118 ? 147.466 92.584  129.301 1.00 90.47  ? 118 SER D N     1 
ATOM   2902 C CA    . SER B 1 118 ? 147.507 92.762  127.855 1.00 89.83  ? 118 SER D CA    1 
ATOM   2903 C C     . SER B 1 118 ? 146.134 93.030  127.255 1.00 91.57  ? 118 SER D C     1 
ATOM   2904 O O     . SER B 1 118 ? 146.058 93.450  126.096 1.00 91.84  ? 118 SER D O     1 
ATOM   2905 C CB    . SER B 1 118 ? 148.117 91.525  127.194 1.00 91.33  ? 118 SER D CB    1 
ATOM   2906 O OG    . SER B 1 118 ? 149.532 91.581  127.213 1.00 89.45  ? 118 SER D OG    1 
ATOM   2907 N N     . ARG B 1 119 ? 145.055 92.807  128.008 1.00 93.40  ? 119 ARG D N     1 
ATOM   2908 C CA    . ARG B 1 119 ? 143.698 92.941  127.497 1.00 94.91  ? 119 ARG D CA    1 
ATOM   2909 C C     . ARG B 1 119 ? 143.022 94.228  127.959 1.00 92.38  ? 119 ARG D C     1 
ATOM   2910 O O     . ARG B 1 119 ? 141.796 94.345  127.862 1.00 90.03  ? 119 ARG D O     1 
ATOM   2911 C CB    . ARG B 1 119 ? 142.855 91.729  127.902 1.00 92.38  ? 119 ARG D CB    1 
ATOM   2912 C CG    . ARG B 1 119 ? 142.883 91.397  129.387 1.00 91.07  ? 119 ARG D CG    1 
ATOM   2913 C CD    . ARG B 1 119 ? 142.128 90.109  129.681 1.00 92.04  ? 119 ARG D CD    1 
ATOM   2914 N NE    . ARG B 1 119 ? 140.696 90.255  129.439 1.00 91.52  ? 119 ARG D NE    1 
ATOM   2915 C CZ    . ARG B 1 119 ? 139.960 89.445  128.688 1.00 90.34  ? 119 ARG D CZ    1 
ATOM   2916 N NH1   . ARG B 1 119 ? 140.480 88.388  128.083 1.00 90.60  ? 119 ARG D NH1   1 
ATOM   2917 N NH2   . ARG B 1 119 ? 138.663 89.700  128.541 1.00 87.11  ? 119 ARG D NH2   1 
ATOM   2918 N N     . TRP B 1 120 ? 143.791 95.192  128.466 1.00 88.10  ? 120 TRP D N     1 
ATOM   2919 C CA    . TRP B 1 120 ? 143.208 96.476  128.837 1.00 86.91  ? 120 TRP D CA    1 
ATOM   2920 C C     . TRP B 1 120 ? 142.904 97.335  127.618 1.00 84.75  ? 120 TRP D C     1 
ATOM   2921 O O     . TRP B 1 120 ? 141.960 98.133  127.647 1.00 80.36  ? 120 TRP D O     1 
ATOM   2922 C CB    . TRP B 1 120 ? 144.141 97.217  129.797 1.00 89.40  ? 120 TRP D CB    1 
ATOM   2923 C CG    . TRP B 1 120 ? 145.119 98.149  129.140 1.00 90.67  ? 120 TRP D CG    1 
ATOM   2924 C CD1   . TRP B 1 120 ? 146.432 97.898  128.869 1.00 90.53  ? 120 TRP D CD1   1 
ATOM   2925 C CD2   . TRP B 1 120 ? 144.867 99.486  128.695 1.00 90.94  ? 120 TRP D CD2   1 
ATOM   2926 N NE1   . TRP B 1 120 ? 147.011 98.993  128.276 1.00 89.32  ? 120 TRP D NE1   1 
ATOM   2927 C CE2   . TRP B 1 120 ? 146.071 99.981  128.157 1.00 89.92  ? 120 TRP D CE2   1 
ATOM   2928 C CE3   . TRP B 1 120 ? 143.739 100.311 128.693 1.00 85.43  ? 120 TRP D CE3   1 
ATOM   2929 C CZ2   . TRP B 1 120 ? 146.178 101.262 127.624 1.00 87.75  ? 120 TRP D CZ2   1 
ATOM   2930 C CZ3   . TRP B 1 120 ? 143.849 101.580 128.164 1.00 85.98  ? 120 TRP D CZ3   1 
ATOM   2931 C CH2   . TRP B 1 120 ? 145.058 102.044 127.637 1.00 85.07  ? 120 TRP D CH2   1 
ATOM   2932 N N     . THR B 1 121 ? 143.684 97.190  126.544 1.00 88.80  ? 121 THR D N     1 
ATOM   2933 C CA    . THR B 1 121 ? 143.422 97.957  125.331 1.00 88.88  ? 121 THR D CA    1 
ATOM   2934 C C     . THR B 1 121 ? 142.063 97.602  124.744 1.00 90.00  ? 121 THR D C     1 
ATOM   2935 O O     . THR B 1 121 ? 141.344 98.477  124.246 1.00 92.28  ? 121 THR D O     1 
ATOM   2936 C CB    . THR B 1 121 ? 144.526 97.710  124.304 1.00 88.77  ? 121 THR D CB    1 
ATOM   2937 O OG1   . THR B 1 121 ? 144.656 96.302  124.069 1.00 94.08  ? 121 THR D OG1   1 
ATOM   2938 C CG2   . THR B 1 121 ? 145.853 98.266  124.799 1.00 85.52  ? 121 THR D CG2   1 
ATOM   2939 N N     . GLU B 1 122 ? 141.696 96.321  124.787 1.00 89.76  ? 122 GLU D N     1 
ATOM   2940 C CA    . GLU B 1 122 ? 140.396 95.906  124.273 1.00 91.12  ? 122 GLU D CA    1 
ATOM   2941 C C     . GLU B 1 122 ? 139.267 96.597  125.027 1.00 88.74  ? 122 GLU D C     1 
ATOM   2942 O O     . GLU B 1 122 ? 138.330 97.130  124.420 1.00 86.51  ? 122 GLU D O     1 
ATOM   2943 C CB    . GLU B 1 122 ? 140.262 94.388  124.379 1.00 96.27  ? 122 GLU D CB    1 
ATOM   2944 C CG    . GLU B 1 122 ? 141.267 93.617  123.541 1.00 99.11  ? 122 GLU D CG    1 
ATOM   2945 C CD    . GLU B 1 122 ? 141.235 92.129  123.821 1.00 101.79 ? 122 GLU D CD    1 
ATOM   2946 O OE1   . GLU B 1 122 ? 140.588 91.723  124.809 1.00 98.48  ? 122 GLU D OE1   1 
ATOM   2947 O OE2   . GLU B 1 122 ? 141.858 91.364  123.056 1.00 106.81 ? 122 GLU D OE2   1 
ATOM   2948 N N     . TYR B 1 123 ? 139.343 96.602  126.359 1.00 86.37  ? 123 TYR D N     1 
ATOM   2949 C CA    . TYR B 1 123 ? 138.310 97.255  127.154 1.00 85.13  ? 123 TYR D CA    1 
ATOM   2950 C C     . TYR B 1 123 ? 138.285 98.754  126.893 1.00 82.03  ? 123 TYR D C     1 
ATOM   2951 O O     . TYR B 1 123 ? 137.211 99.353  126.775 1.00 80.68  ? 123 TYR D O     1 
ATOM   2952 C CB    . TYR B 1 123 ? 138.533 96.975  128.639 1.00 84.58  ? 123 TYR D CB    1 
ATOM   2953 C CG    . TYR B 1 123 ? 137.689 97.834  129.552 1.00 79.29  ? 123 TYR D CG    1 
ATOM   2954 C CD1   . TYR B 1 123 ? 136.385 97.479  129.858 1.00 73.86  ? 123 TYR D CD1   1 
ATOM   2955 C CD2   . TYR B 1 123 ? 138.195 99.001  130.104 1.00 79.06  ? 123 TYR D CD2   1 
ATOM   2956 C CE1   . TYR B 1 123 ? 135.611 98.259  130.687 1.00 73.68  ? 123 TYR D CE1   1 
ATOM   2957 C CE2   . TYR B 1 123 ? 137.428 99.788  130.935 1.00 72.78  ? 123 TYR D CE2   1 
ATOM   2958 C CZ    . TYR B 1 123 ? 136.136 99.413  131.223 1.00 72.86  ? 123 TYR D CZ    1 
ATOM   2959 O OH    . TYR B 1 123 ? 135.365 100.194 132.052 1.00 73.05  ? 123 TYR D OH    1 
ATOM   2960 N N     . CYS B 1 124 ? 139.460 99.379  126.801 1.00 81.97  ? 124 CYS D N     1 
ATOM   2961 C CA    . CYS B 1 124 ? 139.506 100.814 126.548 1.00 77.44  ? 124 CYS D CA    1 
ATOM   2962 C C     . CYS B 1 124 ? 138.872 101.154 125.208 1.00 80.08  ? 124 CYS D C     1 
ATOM   2963 O O     . CYS B 1 124 ? 138.196 102.180 125.074 1.00 78.52  ? 124 CYS D O     1 
ATOM   2964 C CB    . CYS B 1 124 ? 140.948 101.310 126.595 1.00 82.05  ? 124 CYS D CB    1 
ATOM   2965 S SG    . CYS B 1 124 ? 141.209 102.876 125.732 1.00 97.50  ? 124 CYS D SG    1 
ATOM   2966 N N     . ALA B 1 125 ? 139.091 100.314 124.196 1.00 85.15  ? 125 ALA D N     1 
ATOM   2967 C CA    . ALA B 1 125 ? 138.508 100.579 122.886 1.00 83.25  ? 125 ALA D CA    1 
ATOM   2968 C C     . ALA B 1 125 ? 137.016 100.272 122.858 1.00 86.97  ? 125 ALA D C     1 
ATOM   2969 O O     . ALA B 1 125 ? 136.270 100.911 122.107 1.00 89.57  ? 125 ALA D O     1 
ATOM   2970 C CB    . ALA B 1 125 ? 139.232 99.765  121.814 1.00 81.91  ? 125 ALA D CB    1 
ATOM   2971 N N     . THR B 1 126 ? 136.560 99.310  123.661 1.00 84.89  ? 126 THR D N     1 
ATOM   2972 C CA    . THR B 1 126 ? 135.174 98.858  123.592 1.00 82.60  ? 126 THR D CA    1 
ATOM   2973 C C     . THR B 1 126 ? 134.241 99.692  124.470 1.00 86.31  ? 126 THR D C     1 
ATOM   2974 O O     . THR B 1 126 ? 133.262 100.261 123.978 1.00 88.46  ? 126 THR D O     1 
ATOM   2975 C CB    . THR B 1 126 ? 135.092 97.381  123.997 1.00 85.68  ? 126 THR D CB    1 
ATOM   2976 O OG1   . THR B 1 126 ? 135.766 96.577  123.021 1.00 89.92  ? 126 THR D OG1   1 
ATOM   2977 C CG2   . THR B 1 126 ? 133.640 96.933  124.108 1.00 89.31  ? 126 THR D CG2   1 
ATOM   2978 N N     . CYS B 1 127 ? 134.528 99.765  125.767 1.00 86.61  ? 127 CYS D N     1 
ATOM   2979 C CA    . CYS B 1 127 ? 133.597 100.322 126.741 1.00 84.23  ? 127 CYS D CA    1 
ATOM   2980 C C     . CYS B 1 127 ? 133.772 101.818 126.973 1.00 79.23  ? 127 CYS D C     1 
ATOM   2981 O O     . CYS B 1 127 ? 132.979 102.404 127.716 1.00 81.71  ? 127 CYS D O     1 
ATOM   2982 C CB    . CYS B 1 127 ? 133.739 99.584  128.074 1.00 83.47  ? 127 CYS D CB    1 
ATOM   2983 S SG    . CYS B 1 127 ? 133.082 97.900  128.060 1.00 88.29  ? 127 CYS D SG    1 
ATOM   2984 N N     . VAL B 1 128 ? 134.771 102.451 126.370 1.00 78.28  ? 128 VAL D N     1 
ATOM   2985 C CA    . VAL B 1 128 ? 134.995 103.885 126.523 1.00 77.69  ? 128 VAL D CA    1 
ATOM   2986 C C     . VAL B 1 128 ? 134.214 104.601 125.424 1.00 81.08  ? 128 VAL D C     1 
ATOM   2987 O O     . VAL B 1 128 ? 134.510 104.388 124.238 1.00 82.53  ? 128 VAL D O     1 
ATOM   2988 C CB    . VAL B 1 128 ? 136.486 104.234 126.444 1.00 74.79  ? 128 VAL D CB    1 
ATOM   2989 C CG1   . VAL B 1 128 ? 136.695 105.723 126.658 1.00 69.40  ? 128 VAL D CG1   1 
ATOM   2990 C CG2   . VAL B 1 128 ? 137.274 103.434 127.462 1.00 74.27  ? 128 VAL D CG2   1 
ATOM   2991 N N     . PRO B 1 129 ? 133.231 105.438 125.757 1.00 84.07  ? 129 PRO D N     1 
ATOM   2992 C CA    . PRO B 1 129 ? 132.532 106.187 124.707 1.00 85.44  ? 129 PRO D CA    1 
ATOM   2993 C C     . PRO B 1 129 ? 133.504 107.055 123.924 1.00 88.49  ? 129 PRO D C     1 
ATOM   2994 O O     . PRO B 1 129 ? 134.439 107.632 124.482 1.00 86.83  ? 129 PRO D O     1 
ATOM   2995 C CB    . PRO B 1 129 ? 131.518 107.038 125.480 1.00 81.07  ? 129 PRO D CB    1 
ATOM   2996 C CG    . PRO B 1 129 ? 131.401 106.419 126.813 1.00 80.93  ? 129 PRO D CG    1 
ATOM   2997 C CD    . PRO B 1 129 ? 132.682 105.712 127.095 1.00 83.36  ? 129 PRO D CD    1 
ATOM   2998 N N     . ALA B 1 130 ? 133.273 107.148 122.618 1.00 89.55  ? 130 ALA D N     1 
ATOM   2999 C CA    . ALA B 1 130 ? 134.131 107.969 121.779 1.00 88.64  ? 130 ALA D CA    1 
ATOM   3000 C C     . ALA B 1 130 ? 134.047 109.426 122.215 1.00 92.18  ? 130 ALA D C     1 
ATOM   3001 O O     . ALA B 1 130 ? 133.013 109.893 122.701 1.00 97.75  ? 130 ALA D O     1 
ATOM   3002 C CB    . ALA B 1 130 ? 133.733 107.831 120.310 1.00 97.33  ? 130 ALA D CB    1 
ATOM   3003 N N     . LEU B 1 131 ? 135.153 110.145 122.042 1.00 90.76  ? 131 LEU D N     1 
ATOM   3004 C CA    . LEU B 1 131 ? 135.228 111.518 122.520 1.00 95.54  ? 131 LEU D CA    1 
ATOM   3005 C C     . LEU B 1 131 ? 134.087 112.347 121.945 1.00 98.53  ? 131 LEU D C     1 
ATOM   3006 O O     . LEU B 1 131 ? 133.780 112.273 120.753 1.00 100.67 ? 131 LEU D O     1 
ATOM   3007 C CB    . LEU B 1 131 ? 136.572 112.138 122.139 1.00 93.15  ? 131 LEU D CB    1 
ATOM   3008 C CG    . LEU B 1 131 ? 136.857 113.532 122.703 1.00 97.51  ? 131 LEU D CG    1 
ATOM   3009 C CD1   . LEU B 1 131 ? 136.661 113.566 124.209 1.00 97.78  ? 131 LEU D CD1   1 
ATOM   3010 C CD2   . LEU B 1 131 ? 138.266 113.971 122.343 1.00 96.67  ? 131 LEU D CD2   1 
ATOM   3011 N N     . GLY B 1 132 ? 133.457 113.142 122.807 1.00 101.86 ? 132 GLY D N     1 
ATOM   3012 C CA    . GLY B 1 132 ? 132.319 113.947 122.423 1.00 102.43 ? 132 GLY D CA    1 
ATOM   3013 C C     . GLY B 1 132 ? 130.984 113.238 122.482 1.00 103.19 ? 132 GLY D C     1 
ATOM   3014 O O     . GLY B 1 132 ? 129.967 113.841 122.118 1.00 105.73 ? 132 GLY D O     1 
ATOM   3015 N N     . SER B 1 133 ? 130.950 111.986 122.931 1.00 105.30 ? 133 SER D N     1 
ATOM   3016 C CA    . SER B 1 133 ? 129.697 111.248 122.985 1.00 108.04 ? 133 SER D CA    1 
ATOM   3017 C C     . SER B 1 133 ? 128.719 111.925 123.937 1.00 116.22 ? 133 SER D C     1 
ATOM   3018 O O     . SER B 1 133 ? 129.099 112.403 125.009 1.00 120.41 ? 133 SER D O     1 
ATOM   3019 C CB    . SER B 1 133 ? 129.954 109.810 123.432 1.00 102.69 ? 133 SER D CB    1 
ATOM   3020 O OG    . SER B 1 133 ? 130.538 109.049 122.390 1.00 97.40  ? 133 SER D OG    1 
ATOM   3021 N N     . LYS B 1 134 ? 127.448 111.963 123.537 1.00 119.67 ? 134 LYS D N     1 
ATOM   3022 C CA    . LYS B 1 134 ? 126.389 112.574 124.326 1.00 122.70 ? 134 LYS D CA    1 
ATOM   3023 C C     . LYS B 1 134 ? 125.238 111.591 124.473 1.00 123.71 ? 134 LYS D C     1 
ATOM   3024 O O     . LYS B 1 134 ? 124.936 110.833 123.547 1.00 122.34 ? 134 LYS D O     1 
ATOM   3025 C CB    . LYS B 1 134 ? 125.887 113.870 123.682 1.00 121.75 ? 134 LYS D CB    1 
ATOM   3026 C CG    . LYS B 1 134 ? 126.946 114.950 123.566 1.00 122.54 ? 134 LYS D CG    1 
ATOM   3027 C CD    . LYS B 1 134 ? 126.367 116.234 123.000 1.00 125.73 ? 134 LYS D CD    1 
ATOM   3028 C CE    . LYS B 1 134 ? 127.430 117.313 122.868 1.00 129.51 ? 134 LYS D CE    1 
ATOM   3029 N NZ    . LYS B 1 134 ? 126.838 118.648 122.568 1.00 125.33 ? 134 LYS D NZ    1 
ATOM   3030 N N     . MET B 1 135 ? 124.591 111.616 125.640 1.00 125.14 ? 135 MET D N     1 
ATOM   3031 C CA    . MET B 1 135 ? 123.516 110.666 125.908 1.00 124.50 ? 135 MET D CA    1 
ATOM   3032 C C     . MET B 1 135 ? 122.344 110.868 124.956 1.00 127.60 ? 135 MET D C     1 
ATOM   3033 O O     . MET B 1 135 ? 121.732 109.896 124.500 1.00 126.99 ? 135 MET D O     1 
ATOM   3034 C CB    . MET B 1 135 ? 123.053 110.801 127.359 1.00 122.49 ? 135 MET D CB    1 
ATOM   3035 C CG    . MET B 1 135 ? 122.022 109.769 127.790 1.00 123.42 ? 135 MET D CG    1 
ATOM   3036 S SD    . MET B 1 135 ? 122.450 108.081 127.329 1.00 130.93 ? 135 MET D SD    1 
ATOM   3037 C CE    . MET B 1 135 ? 123.245 107.525 128.831 1.00 114.14 ? 135 MET D CE    1 
ATOM   3038 N N     . LYS B 1 136 ? 122.011 112.125 124.651 1.00 130.19 ? 136 LYS D N     1 
ATOM   3039 C CA    . LYS B 1 136 ? 120.869 112.397 123.783 1.00 130.37 ? 136 LYS D CA    1 
ATOM   3040 C C     . LYS B 1 136 ? 121.073 111.803 122.396 1.00 127.19 ? 136 LYS D C     1 
ATOM   3041 O O     . LYS B 1 136 ? 120.141 111.240 121.809 1.00 126.00 ? 136 LYS D O     1 
ATOM   3042 C CB    . LYS B 1 136 ? 120.636 113.904 123.686 1.00 133.53 ? 136 LYS D CB    1 
ATOM   3043 C CG    . LYS B 1 136 ? 120.089 114.534 124.954 1.00 137.46 ? 136 LYS D CG    1 
ATOM   3044 C CD    . LYS B 1 136 ? 118.581 114.383 125.062 1.00 142.41 ? 136 LYS D CD    1 
ATOM   3045 C CE    . LYS B 1 136 ? 117.988 115.449 125.969 1.00 145.44 ? 136 LYS D CE    1 
ATOM   3046 N NZ    . LYS B 1 136 ? 116.578 115.151 126.334 1.00 147.63 ? 136 LYS D NZ    1 
ATOM   3047 N N     . VAL B 1 137 ? 122.283 111.928 121.848 1.00 126.37 ? 137 VAL D N     1 
ATOM   3048 C CA    . VAL B 1 137 ? 122.547 111.404 120.511 1.00 124.93 ? 137 VAL D CA    1 
ATOM   3049 C C     . VAL B 1 137 ? 122.368 109.892 120.486 1.00 125.38 ? 137 VAL D C     1 
ATOM   3050 O O     . VAL B 1 137 ? 121.745 109.341 119.571 1.00 123.16 ? 137 VAL D O     1 
ATOM   3051 C CB    . VAL B 1 137 ? 123.958 111.815 120.048 1.00 122.19 ? 137 VAL D CB    1 
ATOM   3052 C CG1   . VAL B 1 137 ? 124.286 111.183 118.703 1.00 118.17 ? 137 VAL D CG1   1 
ATOM   3053 C CG2   . VAL B 1 137 ? 124.070 113.331 119.972 1.00 119.91 ? 137 VAL D CG2   1 
ATOM   3054 N N     . ILE B 1 138 ? 122.904 109.196 121.491 1.00 127.16 ? 138 ILE D N     1 
ATOM   3055 C CA    . ILE B 1 138 ? 122.787 107.741 121.519 1.00 126.96 ? 138 ILE D CA    1 
ATOM   3056 C C     . ILE B 1 138 ? 121.334 107.329 121.723 1.00 129.71 ? 138 ILE D C     1 
ATOM   3057 O O     . ILE B 1 138 ? 120.869 106.339 121.146 1.00 131.04 ? 138 ILE D O     1 
ATOM   3058 C CB    . ILE B 1 138 ? 123.703 107.142 122.603 1.00 123.57 ? 138 ILE D CB    1 
ATOM   3059 C CG1   . ILE B 1 138 ? 125.115 107.735 122.519 1.00 120.73 ? 138 ILE D CG1   1 
ATOM   3060 C CG2   . ILE B 1 138 ? 123.761 105.624 122.475 1.00 121.95 ? 138 ILE D CG2   1 
ATOM   3061 C CD1   . ILE B 1 138 ? 125.821 107.494 121.198 1.00 118.87 ? 138 ILE D CD1   1 
ATOM   3062 N N     . LYS B 1 139 ? 120.594 108.073 122.549 1.00 129.96 ? 139 LYS D N     1 
ATOM   3063 C CA    . LYS B 1 139 ? 119.172 107.787 122.715 1.00 128.67 ? 139 LYS D CA    1 
ATOM   3064 C C     . LYS B 1 139 ? 118.429 107.943 121.396 1.00 129.44 ? 139 LYS D C     1 
ATOM   3065 O O     . LYS B 1 139 ? 117.559 107.129 121.063 1.00 125.93 ? 139 LYS D O     1 
ATOM   3066 C CB    . LYS B 1 139 ? 118.573 108.699 123.786 1.00 127.76 ? 139 LYS D CB    1 
ATOM   3067 C CG    . LYS B 1 139 ? 118.197 107.965 125.065 1.00 126.72 ? 139 LYS D CG    1 
ATOM   3068 C CD    . LYS B 1 139 ? 118.031 108.911 126.242 1.00 130.84 ? 139 LYS D CD    1 
ATOM   3069 C CE    . LYS B 1 139 ? 118.133 108.165 127.564 1.00 134.10 ? 139 LYS D CE    1 
ATOM   3070 N NZ    . LYS B 1 139 ? 118.240 109.085 128.728 1.00 140.61 ? 139 LYS D NZ    1 
ATOM   3071 N N     . ALA B 1 140 ? 118.762 108.981 120.628 1.00 129.73 ? 140 ALA D N     1 
ATOM   3072 C CA    . ALA B 1 140 ? 118.177 109.131 119.300 1.00 127.45 ? 140 ALA D CA    1 
ATOM   3073 C C     . ALA B 1 140 ? 118.570 107.968 118.397 1.00 126.97 ? 140 ALA D C     1 
ATOM   3074 O O     . ALA B 1 140 ? 117.779 107.530 117.554 1.00 127.60 ? 140 ALA D O     1 
ATOM   3075 C CB    . ALA B 1 140 ? 118.611 110.460 118.683 1.00 127.18 ? 140 ALA D CB    1 
ATOM   3076 N N     . SER B 1 141 ? 119.793 107.455 118.561 1.00 128.50 ? 141 SER D N     1 
ATOM   3077 C CA    . SER B 1 141 ? 120.235 106.322 117.754 1.00 129.80 ? 141 SER D CA    1 
ATOM   3078 C C     . SER B 1 141 ? 119.365 105.096 118.001 1.00 131.97 ? 141 SER D C     1 
ATOM   3079 O O     . SER B 1 141 ? 119.025 104.367 117.062 1.00 130.33 ? 141 SER D O     1 
ATOM   3080 C CB    . SER B 1 141 ? 121.701 106.008 118.051 1.00 126.16 ? 141 SER D CB    1 
ATOM   3081 O OG    . SER B 1 141 ? 121.970 104.626 117.891 1.00 124.07 ? 141 SER D OG    1 
ATOM   3082 N N     . GLY B 1 142 ? 118.999 104.848 119.257 1.00 129.93 ? 142 GLY D N     1 
ATOM   3083 C CA    . GLY B 1 142 ? 118.118 103.747 119.584 1.00 127.46 ? 142 GLY D CA    1 
ATOM   3084 C C     . GLY B 1 142 ? 118.793 102.412 119.797 1.00 126.98 ? 142 GLY D C     1 
ATOM   3085 O O     . GLY B 1 142 ? 118.095 101.404 119.954 1.00 129.09 ? 142 GLY D O     1 
ATOM   3086 N N     . ASP B 1 143 ? 120.122 102.364 119.809 1.00 125.35 ? 143 ASP D N     1 
ATOM   3087 C CA    . ASP B 1 143 ? 120.836 101.117 120.055 1.00 123.32 ? 143 ASP D CA    1 
ATOM   3088 C C     . ASP B 1 143 ? 120.916 100.869 121.557 1.00 122.85 ? 143 ASP D C     1 
ATOM   3089 O O     . ASP B 1 143 ? 121.549 101.639 122.287 1.00 121.64 ? 143 ASP D O     1 
ATOM   3090 C CB    . ASP B 1 143 ? 122.233 101.172 119.440 1.00 121.00 ? 143 ASP D CB    1 
ATOM   3091 C CG    . ASP B 1 143 ? 122.760 99.800  119.069 1.00 120.98 ? 143 ASP D CG    1 
ATOM   3092 O OD1   . ASP B 1 143 ? 122.740 98.899  119.934 1.00 117.81 ? 143 ASP D OD1   1 
ATOM   3093 O OD2   . ASP B 1 143 ? 123.194 99.622  117.911 1.00 126.90 ? 143 ASP D OD2   1 
ATOM   3094 N N     . ALA B 1 144 ? 120.278 99.790  122.016 1.00 120.33 ? 144 ALA D N     1 
ATOM   3095 C CA    . ALA B 1 144 ? 120.252 99.501  123.447 1.00 119.55 ? 144 ALA D CA    1 
ATOM   3096 C C     . ALA B 1 144 ? 121.654 99.255  123.988 1.00 118.16 ? 144 ALA D C     1 
ATOM   3097 O O     . ALA B 1 144 ? 121.971 99.650  125.116 1.00 114.85 ? 144 ALA D O     1 
ATOM   3098 C CB    . ALA B 1 144 ? 119.355 98.295  123.720 1.00 121.21 ? 144 ALA D CB    1 
ATOM   3099 N N     . ALA B 1 145 ? 122.506 98.592  123.202 1.00 118.91 ? 145 ALA D N     1 
ATOM   3100 C CA    . ALA B 1 145 ? 123.860 98.303  123.663 1.00 115.28 ? 145 ALA D CA    1 
ATOM   3101 C C     . ALA B 1 145 ? 124.635 99.586  123.936 1.00 111.49 ? 145 ALA D C     1 
ATOM   3102 O O     . ALA B 1 145 ? 125.337 99.694  124.948 1.00 109.89 ? 145 ALA D O     1 
ATOM   3103 C CB    . ALA B 1 145 ? 124.591 97.447  122.630 1.00 114.12 ? 145 ALA D CB    1 
ATOM   3104 N N     . MET B 1 146 ? 124.513 100.574 123.048 1.00 111.61 ? 146 MET D N     1 
ATOM   3105 C CA    . MET B 1 146 ? 125.221 101.831 123.252 1.00 111.20 ? 146 MET D CA    1 
ATOM   3106 C C     . MET B 1 146 ? 124.647 102.610 124.429 1.00 113.47 ? 146 MET D C     1 
ATOM   3107 O O     . MET B 1 146 ? 125.394 103.277 125.151 1.00 111.27 ? 146 MET D O     1 
ATOM   3108 C CB    . MET B 1 146 ? 125.167 102.671 121.979 1.00 110.90 ? 146 MET D CB    1 
ATOM   3109 C CG    . MET B 1 146 ? 126.053 102.154 120.859 1.00 114.51 ? 146 MET D CG    1 
ATOM   3110 S SD    . MET B 1 146 ? 127.788 102.034 121.335 1.00 116.65 ? 146 MET D SD    1 
ATOM   3111 C CE    . MET B 1 146 ? 128.253 100.494 120.548 1.00 110.38 ? 146 MET D CE    1 
ATOM   3112 N N     . ILE B 1 147 ? 123.333 102.541 124.640 1.00 114.73 ? 147 ILE D N     1 
ATOM   3113 C CA    . ILE B 1 147 ? 122.742 103.173 125.815 1.00 111.90 ? 147 ILE D CA    1 
ATOM   3114 C C     . ILE B 1 147 ? 123.305 102.548 127.084 1.00 108.05 ? 147 ILE D C     1 
ATOM   3115 O O     . ILE B 1 147 ? 123.675 103.249 128.035 1.00 101.72 ? 147 ILE D O     1 
ATOM   3116 C CB    . ILE B 1 147 ? 121.207 103.062 125.766 1.00 113.71 ? 147 ILE D CB    1 
ATOM   3117 C CG1   . ILE B 1 147 ? 120.638 103.818 124.563 1.00 114.01 ? 147 ILE D CG1   1 
ATOM   3118 C CG2   . ILE B 1 147 ? 120.597 103.605 127.040 1.00 112.37 ? 147 ILE D CG2   1 
ATOM   3119 C CD1   . ILE B 1 147 ? 120.979 105.290 124.533 1.00 114.80 ? 147 ILE D CD1   1 
ATOM   3120 N N     . GLN B 1 148 ? 123.374 101.217 127.116 1.00 110.38 ? 148 GLN D N     1 
ATOM   3121 C CA    . GLN B 1 148 ? 123.941 100.538 128.275 1.00 107.60 ? 148 GLN D CA    1 
ATOM   3122 C C     . GLN B 1 148 ? 125.396 100.936 128.481 1.00 106.71 ? 148 GLN D C     1 
ATOM   3123 O O     . GLN B 1 148 ? 125.830 101.154 129.616 1.00 104.16 ? 148 GLN D O     1 
ATOM   3124 C CB    . GLN B 1 148 ? 123.821 99.023  128.111 1.00 106.74 ? 148 GLN D CB    1 
ATOM   3125 C CG    . GLN B 1 148 ? 124.293 98.234  129.324 1.00 103.11 ? 148 GLN D CG    1 
ATOM   3126 C CD    . GLN B 1 148 ? 124.352 96.735  129.081 1.00 105.06 ? 148 GLN D CD    1 
ATOM   3127 O OE1   . GLN B 1 148 ? 125.076 96.019  129.772 1.00 104.22 ? 148 GLN D OE1   1 
ATOM   3128 N NE2   . GLN B 1 148 ? 123.577 96.249  128.115 1.00 108.98 ? 148 GLN D NE2   1 
ATOM   3129 N N     . MET B 1 149 ? 126.167 101.027 127.395 1.00 102.77 ? 149 MET D N     1 
ATOM   3130 C CA    . MET B 1 149 ? 127.574 101.391 127.524 1.00 96.56  ? 149 MET D CA    1 
ATOM   3131 C C     . MET B 1 149 ? 127.731 102.818 128.041 1.00 95.95  ? 149 MET D C     1 
ATOM   3132 O O     . MET B 1 149 ? 128.614 103.092 128.861 1.00 92.54  ? 149 MET D O     1 
ATOM   3133 C CB    . MET B 1 149 ? 128.290 101.197 126.183 1.00 96.64  ? 149 MET D CB    1 
ATOM   3134 C CG    . MET B 1 149 ? 128.437 102.440 125.315 1.00 103.52 ? 149 MET D CG    1 
ATOM   3135 S SD    . MET B 1 149 ? 129.913 103.402 125.690 1.00 90.15  ? 149 MET D SD    1 
ATOM   3136 C CE    . MET B 1 149 ? 131.178 102.393 124.925 1.00 90.18  ? 149 MET D CE    1 
ATOM   3137 N N     . MET B 1 150 ? 126.878 103.739 127.588 1.00 98.06  ? 150 MET D N     1 
ATOM   3138 C CA    . MET B 1 150 ? 126.951 105.112 128.080 1.00 98.86  ? 150 MET D CA    1 
ATOM   3139 C C     . MET B 1 150 ? 126.569 105.193 129.553 1.00 98.63  ? 150 MET D C     1 
ATOM   3140 O O     . MET B 1 150 ? 127.210 105.913 130.331 1.00 92.31  ? 150 MET D O     1 
ATOM   3141 C CB    . MET B 1 150 ? 126.047 106.015 127.245 1.00 99.89  ? 150 MET D CB    1 
ATOM   3142 C CG    . MET B 1 150 ? 126.415 107.481 127.330 1.00 104.47 ? 150 MET D CG    1 
ATOM   3143 S SD    . MET B 1 150 ? 127.851 107.874 126.316 1.00 111.90 ? 150 MET D SD    1 
ATOM   3144 C CE    . MET B 1 150 ? 128.361 109.431 127.036 1.00 105.60 ? 150 MET D CE    1 
ATOM   3145 N N     . LYS B 1 151 ? 125.525 104.465 129.955 1.00 102.02 ? 151 LYS D N     1 
ATOM   3146 C CA    . LYS B 1 151 ? 125.152 104.439 131.365 1.00 98.05  ? 151 LYS D CA    1 
ATOM   3147 C C     . LYS B 1 151 ? 126.271 103.846 132.211 1.00 89.18  ? 151 LYS D C     1 
ATOM   3148 O O     . LYS B 1 151 ? 126.555 104.332 133.312 1.00 88.67  ? 151 LYS D O     1 
ATOM   3149 C CB    . LYS B 1 151 ? 123.859 103.646 131.550 1.00 102.40 ? 151 LYS D CB    1 
ATOM   3150 C CG    . LYS B 1 151 ? 122.647 104.254 130.857 1.00 104.13 ? 151 LYS D CG    1 
ATOM   3151 C CD    . LYS B 1 151 ? 122.231 105.569 131.497 1.00 103.39 ? 151 LYS D CD    1 
ATOM   3152 C CE    . LYS B 1 151 ? 120.957 106.111 130.871 1.00 109.95 ? 151 LYS D CE    1 
ATOM   3153 N NZ    . LYS B 1 151 ? 120.638 107.485 131.349 1.00 120.60 ? 151 LYS D NZ    1 
ATOM   3154 N N     . ASP B 1 152 ? 126.916 102.790 131.710 1.00 83.61  ? 152 ASP D N     1 
ATOM   3155 C CA    . ASP B 1 152 ? 128.045 102.202 132.419 1.00 86.15  ? 152 ASP D CA    1 
ATOM   3156 C C     . ASP B 1 152 ? 129.189 103.198 132.550 1.00 86.00  ? 152 ASP D C     1 
ATOM   3157 O O     . ASP B 1 152 ? 129.822 103.292 133.606 1.00 84.65  ? 152 ASP D O     1 
ATOM   3158 C CB    . ASP B 1 152 ? 128.513 100.943 131.693 1.00 86.46  ? 152 ASP D CB    1 
ATOM   3159 C CG    . ASP B 1 152 ? 127.565 99.778  131.878 1.00 89.99  ? 152 ASP D CG    1 
ATOM   3160 O OD1   . ASP B 1 152 ? 126.505 99.967  132.511 1.00 88.11  ? 152 ASP D OD1   1 
ATOM   3161 O OD2   . ASP B 1 152 ? 127.881 98.670  131.395 1.00 94.95  ? 152 ASP D OD2   1 
ATOM   3162 N N     . HIS B 1 153 ? 129.474 103.945 131.483 1.00 79.56  ? 153 HIS D N     1 
ATOM   3163 C CA    . HIS B 1 153 ? 130.525 104.955 131.547 1.00 76.92  ? 153 HIS D CA    1 
ATOM   3164 C C     . HIS B 1 153 ? 130.204 106.003 132.604 1.00 76.90  ? 153 HIS D C     1 
ATOM   3165 O O     . HIS B 1 153 ? 131.066 106.379 133.409 1.00 75.85  ? 153 HIS D O     1 
ATOM   3166 C CB    . HIS B 1 153 ? 130.703 105.600 130.171 1.00 77.84  ? 153 HIS D CB    1 
ATOM   3167 C CG    . HIS B 1 153 ? 131.353 106.949 130.207 1.00 73.47  ? 153 HIS D CG    1 
ATOM   3168 N ND1   . HIS B 1 153 ? 132.698 107.132 129.974 1.00 66.23  ? 153 HIS D ND1   1 
ATOM   3169 C CD2   . HIS B 1 153 ? 130.838 108.182 130.423 1.00 75.44  ? 153 HIS D CD2   1 
ATOM   3170 C CE1   . HIS B 1 153 ? 132.987 108.418 130.060 1.00 65.57  ? 153 HIS D CE1   1 
ATOM   3171 N NE2   . HIS B 1 153 ? 131.875 109.077 130.332 1.00 70.97  ? 153 HIS D NE2   1 
ATOM   3172 N N     . ASN B 1 154 ? 128.958 106.479 132.628 1.00 77.65  ? 154 ASN D N     1 
ATOM   3173 C CA    . ASN B 1 154 ? 128.583 107.485 133.618 1.00 76.69  ? 154 ASN D CA    1 
ATOM   3174 C C     . ASN B 1 154 ? 128.708 106.937 135.037 1.00 71.75  ? 154 ASN D C     1 
ATOM   3175 O O     . ASN B 1 154 ? 129.242 107.611 135.929 1.00 65.89  ? 154 ASN D O     1 
ATOM   3176 C CB    . ASN B 1 154 ? 127.160 107.974 133.355 1.00 82.10  ? 154 ASN D CB    1 
ATOM   3177 C CG    . ASN B 1 154 ? 127.067 108.862 132.131 1.00 90.10  ? 154 ASN D CG    1 
ATOM   3178 O OD1   . ASN B 1 154 ? 128.081 109.265 131.565 1.00 91.44  ? 154 ASN D OD1   1 
ATOM   3179 N ND2   . ASN B 1 154 ? 125.845 109.183 131.723 1.00 96.14  ? 154 ASN D ND2   1 
ATOM   3180 N N     . SER B 1 155 ? 128.227 105.712 135.265 1.00 74.34  ? 155 SER D N     1 
ATOM   3181 C CA    . SER B 1 155 ? 128.299 105.133 136.603 1.00 70.92  ? 155 SER D CA    1 
ATOM   3182 C C     . SER B 1 155 ? 129.743 104.928 137.034 1.00 68.30  ? 155 SER D C     1 
ATOM   3183 O O     . SER B 1 155 ? 130.094 105.163 138.197 1.00 71.42  ? 155 SER D O     1 
ATOM   3184 C CB    . SER B 1 155 ? 127.543 103.808 136.646 1.00 71.91  ? 155 SER D CB    1 
ATOM   3185 O OG    . SER B 1 155 ? 127.966 102.949 135.603 1.00 76.81  ? 155 SER D OG    1 
ATOM   3186 N N     . LEU B 1 156 ? 130.593 104.469 136.114 1.00 60.40  ? 156 LEU D N     1 
ATOM   3187 C CA    . LEU B 1 156 ? 132.000 104.282 136.437 1.00 60.96  ? 156 LEU D CA    1 
ATOM   3188 C C     . LEU B 1 156 ? 132.660 105.608 136.778 1.00 60.23  ? 156 LEU D C     1 
ATOM   3189 O O     . LEU B 1 156 ? 133.469 105.686 137.709 1.00 60.73  ? 156 LEU D O     1 
ATOM   3190 C CB    . LEU B 1 156 ? 132.717 103.608 135.271 1.00 61.09  ? 156 LEU D CB    1 
ATOM   3191 C CG    . LEU B 1 156 ? 134.133 103.126 135.568 1.00 61.29  ? 156 LEU D CG    1 
ATOM   3192 C CD1   . LEU B 1 156 ? 134.108 101.968 136.540 1.00 62.04  ? 156 LEU D CD1   1 
ATOM   3193 C CD2   . LEU B 1 156 ? 134.834 102.725 134.287 1.00 65.86  ? 156 LEU D CD2   1 
ATOM   3194 N N     . LEU B 1 157 ? 132.328 106.667 136.037 1.00 55.20  ? 157 LEU D N     1 
ATOM   3195 C CA    . LEU B 1 157 ? 132.860 107.981 136.379 1.00 54.57  ? 157 LEU D CA    1 
ATOM   3196 C C     . LEU B 1 157 ? 132.424 108.395 137.777 1.00 56.03  ? 157 LEU D C     1 
ATOM   3197 O O     . LEU B 1 157 ? 133.233 108.903 138.563 1.00 55.75  ? 157 LEU D O     1 
ATOM   3198 C CB    . LEU B 1 157 ? 132.410 109.020 135.352 1.00 58.77  ? 157 LEU D CB    1 
ATOM   3199 C CG    . LEU B 1 157 ? 133.067 108.999 133.968 1.00 61.71  ? 157 LEU D CG    1 
ATOM   3200 C CD1   . LEU B 1 157 ? 132.721 110.269 133.207 1.00 59.15  ? 157 LEU D CD1   1 
ATOM   3201 C CD2   . LEU B 1 157 ? 134.572 108.832 134.059 1.00 60.57  ? 157 LEU D CD2   1 
ATOM   3202 N N     . ARG B 1 158 ? 131.151 108.173 138.114 1.00 59.62  ? 158 ARG D N     1 
ATOM   3203 C CA    . ARG B 1 158 ? 130.664 108.553 139.438 1.00 58.08  ? 158 ARG D CA    1 
ATOM   3204 C C     . ARG B 1 158 ? 131.403 107.797 140.539 1.00 52.85  ? 158 ARG D C     1 
ATOM   3205 O O     . ARG B 1 158 ? 131.844 108.390 141.533 1.00 52.42  ? 158 ARG D O     1 
ATOM   3206 C CB    . ARG B 1 158 ? 129.159 108.304 139.532 1.00 63.37  ? 158 ARG D CB    1 
ATOM   3207 C CG    . ARG B 1 158 ? 128.313 109.427 138.947 1.00 67.47  ? 158 ARG D CG    1 
ATOM   3208 C CD    . ARG B 1 158 ? 127.159 108.894 138.112 1.00 72.64  ? 158 ARG D CD    1 
ATOM   3209 N NE    . ARG B 1 158 ? 126.564 109.932 137.279 1.00 75.18  ? 158 ARG D NE    1 
ATOM   3210 C CZ    . ARG B 1 158 ? 125.487 109.761 136.524 1.00 80.63  ? 158 ARG D CZ    1 
ATOM   3211 N NH1   . ARG B 1 158 ? 124.860 108.598 136.466 1.00 80.91  ? 158 ARG D NH1   1 
ATOM   3212 N NH2   . ARG B 1 158 ? 125.029 110.783 135.807 1.00 85.61  ? 158 ARG D NH2   1 
ATOM   3213 N N     . VAL B 1 159 ? 131.553 106.481 140.377 1.00 48.87  ? 159 VAL D N     1 
ATOM   3214 C CA    . VAL B 1 159 ? 132.216 105.682 141.405 1.00 42.66  ? 159 VAL D CA    1 
ATOM   3215 C C     . VAL B 1 159 ? 133.677 106.092 141.543 1.00 48.03  ? 159 VAL D C     1 
ATOM   3216 O O     . VAL B 1 159 ? 134.194 106.244 142.660 1.00 54.38  ? 159 VAL D O     1 
ATOM   3217 C CB    . VAL B 1 159 ? 132.080 104.183 141.090 1.00 42.09  ? 159 VAL D CB    1 
ATOM   3218 C CG1   . VAL B 1 159 ? 133.070 103.378 141.908 1.00 46.73  ? 159 VAL D CG1   1 
ATOM   3219 C CG2   . VAL B 1 159 ? 130.667 103.715 141.364 1.00 52.53  ? 159 VAL D CG2   1 
ATOM   3220 N N     . CYS B 1 160 ? 134.370 106.268 140.416 1.00 48.16  ? 160 CYS D N     1 
ATOM   3221 C CA    . CYS B 1 160 ? 135.776 106.646 140.476 1.00 44.13  ? 160 CYS D CA    1 
ATOM   3222 C C     . CYS B 1 160 ? 135.948 108.009 141.126 1.00 38.67  ? 160 CYS D C     1 
ATOM   3223 O O     . CYS B 1 160 ? 136.906 108.231 141.872 1.00 39.45  ? 160 CYS D O     1 
ATOM   3224 C CB    . CYS B 1 160 ? 136.380 106.637 139.075 1.00 49.20  ? 160 CYS D CB    1 
ATOM   3225 S SG    . CYS B 1 160 ? 136.565 104.986 138.374 1.00 70.52  ? 160 CYS D SG    1 
ATOM   3226 N N     . VAL B 1 161 ? 135.023 108.935 140.871 1.00 39.23  ? 161 VAL D N     1 
ATOM   3227 C CA    . VAL B 1 161 ? 135.124 110.254 141.483 1.00 41.12  ? 161 VAL D CA    1 
ATOM   3228 C C     . VAL B 1 161 ? 134.881 110.171 142.984 1.00 45.71  ? 161 VAL D C     1 
ATOM   3229 O O     . VAL B 1 161 ? 135.539 110.863 143.771 1.00 49.79  ? 161 VAL D O     1 
ATOM   3230 C CB    . VAL B 1 161 ? 134.151 111.227 140.801 1.00 46.17  ? 161 VAL D CB    1 
ATOM   3231 C CG1   . VAL B 1 161 ? 133.980 112.478 141.641 1.00 49.70  ? 161 VAL D CG1   1 
ATOM   3232 C CG2   . VAL B 1 161 ? 134.663 111.573 139.420 1.00 52.47  ? 161 VAL D CG2   1 
ATOM   3233 N N     . ARG B 1 162 ? 133.932 109.338 143.413 1.00 44.63  ? 162 ARG D N     1 
ATOM   3234 C CA    . ARG B 1 162 ? 133.715 109.170 144.847 1.00 39.21  ? 162 ARG D CA    1 
ATOM   3235 C C     . ARG B 1 162 ? 134.969 108.626 145.523 1.00 35.55  ? 162 ARG D C     1 
ATOM   3236 O O     . ARG B 1 162 ? 135.393 109.120 146.578 1.00 39.98  ? 162 ARG D O     1 
ATOM   3237 C CB    . ARG B 1 162 ? 132.526 108.242 145.091 1.00 43.17  ? 162 ARG D CB    1 
ATOM   3238 C CG    . ARG B 1 162 ? 131.205 108.965 145.299 1.00 46.41  ? 162 ARG D CG    1 
ATOM   3239 C CD    . ARG B 1 162 ? 130.022 108.109 144.877 1.00 43.03  ? 162 ARG D CD    1 
ATOM   3240 N NE    . ARG B 1 162 ? 129.631 107.165 145.916 1.00 43.56  ? 162 ARG D NE    1 
ATOM   3241 C CZ    . ARG B 1 162 ? 128.981 107.496 147.024 1.00 48.07  ? 162 ARG D CZ    1 
ATOM   3242 N NH1   . ARG B 1 162 ? 128.631 108.747 147.274 1.00 46.68  ? 162 ARG D NH1   1 
ATOM   3243 N NH2   . ARG B 1 162 ? 128.674 106.548 147.904 1.00 52.28  ? 162 ARG D NH2   1 
ATOM   3244 N N     . ILE B 1 163 ? 135.585 107.609 144.917 1.00 36.59  ? 163 ILE D N     1 
ATOM   3245 C CA    . ILE B 1 163 ? 136.801 107.040 145.491 1.00 34.01  ? 163 ILE D CA    1 
ATOM   3246 C C     . ILE B 1 163 ? 137.914 108.079 145.516 1.00 36.94  ? 163 ILE D C     1 
ATOM   3247 O O     . ILE B 1 163 ? 138.691 108.158 146.476 1.00 39.76  ? 163 ILE D O     1 
ATOM   3248 C CB    . ILE B 1 163 ? 137.220 105.781 144.711 1.00 35.24  ? 163 ILE D CB    1 
ATOM   3249 C CG1   . ILE B 1 163 ? 136.297 104.617 145.062 1.00 37.98  ? 163 ILE D CG1   1 
ATOM   3250 C CG2   . ILE B 1 163 ? 138.658 105.424 145.019 1.00 39.87  ? 163 ILE D CG2   1 
ATOM   3251 C CD1   . ILE B 1 163 ? 136.396 103.451 144.112 1.00 44.57  ? 163 ILE D CD1   1 
ATOM   3252 N N     . GLU B 1 164 ? 138.016 108.887 144.459 1.00 42.73  ? 164 GLU D N     1 
ATOM   3253 C CA    . GLU B 1 164 ? 139.035 109.930 144.417 1.00 40.69  ? 164 GLU D CA    1 
ATOM   3254 C C     . GLU B 1 164 ? 138.834 110.937 145.539 1.00 41.28  ? 164 GLU D C     1 
ATOM   3255 O O     . GLU B 1 164 ? 139.802 111.366 146.174 1.00 49.79  ? 164 GLU D O     1 
ATOM   3256 C CB    . GLU B 1 164 ? 139.006 110.628 143.058 1.00 44.38  ? 164 GLU D CB    1 
ATOM   3257 C CG    . GLU B 1 164 ? 139.811 111.916 142.981 1.00 42.76  ? 164 GLU D CG    1 
ATOM   3258 C CD    . GLU B 1 164 ? 139.758 112.547 141.602 1.00 56.38  ? 164 GLU D CD    1 
ATOM   3259 O OE1   . GLU B 1 164 ? 138.704 112.446 140.941 1.00 53.44  ? 164 GLU D OE1   1 
ATOM   3260 O OE2   . GLU B 1 164 ? 140.769 113.144 141.179 1.00 68.10  ? 164 GLU D OE2   1 
ATOM   3261 N N     . VAL B 1 165 ? 137.587 111.334 145.794 1.00 36.81  ? 165 VAL D N     1 
ATOM   3262 C CA    . VAL B 1 165 ? 137.323 112.289 146.869 1.00 36.37  ? 165 VAL D CA    1 
ATOM   3263 C C     . VAL B 1 165 ? 137.710 111.696 148.217 1.00 32.60  ? 165 VAL D C     1 
ATOM   3264 O O     . VAL B 1 165 ? 138.333 112.365 149.058 1.00 33.83  ? 165 VAL D O     1 
ATOM   3265 C CB    . VAL B 1 165 ? 135.847 112.718 146.849 1.00 39.97  ? 165 VAL D CB    1 
ATOM   3266 C CG1   . VAL B 1 165 ? 135.507 113.486 148.109 1.00 37.41  ? 165 VAL D CG1   1 
ATOM   3267 C CG2   . VAL B 1 165 ? 135.559 113.553 145.621 1.00 44.35  ? 165 VAL D CG2   1 
ATOM   3268 N N     . TRP B 1 166 ? 137.338 110.438 148.455 1.00 34.73  ? 166 TRP D N     1 
ATOM   3269 C CA    . TRP B 1 166 ? 137.692 109.825 149.731 1.00 30.85  ? 166 TRP D CA    1 
ATOM   3270 C C     . TRP B 1 166 ? 139.201 109.752 149.902 1.00 33.26  ? 166 TRP D C     1 
ATOM   3271 O O     . TRP B 1 166 ? 139.721 110.022 150.991 1.00 43.87  ? 166 TRP D O     1 
ATOM   3272 C CB    . TRP B 1 166 ? 137.090 108.432 149.858 1.00 35.05  ? 166 TRP D CB    1 
ATOM   3273 C CG    . TRP B 1 166 ? 137.412 107.814 151.175 1.00 34.96  ? 166 TRP D CG    1 
ATOM   3274 C CD1   . TRP B 1 166 ? 136.672 107.888 152.312 1.00 43.97  ? 166 TRP D CD1   1 
ATOM   3275 C CD2   . TRP B 1 166 ? 138.568 107.039 151.500 1.00 36.16  ? 166 TRP D CD2   1 
ATOM   3276 N NE1   . TRP B 1 166 ? 137.289 107.202 153.325 1.00 45.69  ? 166 TRP D NE1   1 
ATOM   3277 C CE2   . TRP B 1 166 ? 138.457 106.670 152.850 1.00 40.23  ? 166 TRP D CE2   1 
ATOM   3278 C CE3   . TRP B 1 166 ? 139.684 106.615 150.777 1.00 42.67  ? 166 TRP D CE3   1 
ATOM   3279 C CZ2   . TRP B 1 166 ? 139.416 105.900 153.494 1.00 41.48  ? 166 TRP D CZ2   1 
ATOM   3280 C CZ3   . TRP B 1 166 ? 140.636 105.850 151.419 1.00 47.10  ? 166 TRP D CZ3   1 
ATOM   3281 C CH2   . TRP B 1 166 ? 140.497 105.501 152.763 1.00 44.01  ? 166 TRP D CH2   1 
ATOM   3282 N N     . LYS B 1 167 ? 139.925 109.372 148.849 1.00 34.52  ? 167 LYS D N     1 
ATOM   3283 C CA    . LYS B 1 167 ? 141.377 109.324 148.966 1.00 36.50  ? 167 LYS D CA    1 
ATOM   3284 C C     . LYS B 1 167 ? 141.963 110.715 149.147 1.00 35.97  ? 167 LYS D C     1 
ATOM   3285 O O     . LYS B 1 167 ? 142.995 110.866 149.805 1.00 38.83  ? 167 LYS D O     1 
ATOM   3286 C CB    . LYS B 1 167 ? 141.994 108.643 147.748 1.00 40.84  ? 167 LYS D CB    1 
ATOM   3287 C CG    . LYS B 1 167 ? 143.506 108.471 147.834 1.00 45.00  ? 167 LYS D CG    1 
ATOM   3288 C CD    . LYS B 1 167 ? 143.914 107.597 149.014 1.00 43.68  ? 167 LYS D CD    1 
ATOM   3289 C CE    . LYS B 1 167 ? 145.426 107.429 149.121 1.00 45.52  ? 167 LYS D CE    1 
ATOM   3290 N NZ    . LYS B 1 167 ? 146.146 107.733 147.855 1.00 51.46  ? 167 LYS D NZ    1 
ATOM   3291 N N     . ALA B 1 168 ? 141.323 111.741 148.584 1.00 32.57  ? 168 ALA D N     1 
ATOM   3292 C CA    . ALA B 1 168 ? 141.772 113.107 148.822 1.00 31.53  ? 168 ALA D CA    1 
ATOM   3293 C C     . ALA B 1 168 ? 141.694 113.448 150.302 1.00 38.03  ? 168 ALA D C     1 
ATOM   3294 O O     . ALA B 1 168 ? 142.647 113.983 150.881 1.00 44.40  ? 168 ALA D O     1 
ATOM   3295 C CB    . ALA B 1 168 ? 140.933 114.086 148.002 1.00 28.99  ? 168 ALA D CB    1 
ATOM   3296 N N     . ARG B 1 169 ? 140.565 113.131 150.940 1.00 40.46  ? 169 ARG D N     1 
ATOM   3297 C CA    . ARG B 1 169 ? 140.448 113.389 152.376 1.00 32.45  ? 169 ARG D CA    1 
ATOM   3298 C C     . ARG B 1 169 ? 141.467 112.576 153.168 1.00 34.85  ? 169 ARG D C     1 
ATOM   3299 O O     . ARG B 1 169 ? 142.129 113.100 154.075 1.00 40.74  ? 169 ARG D O     1 
ATOM   3300 C CB    . ARG B 1 169 ? 139.039 113.071 152.862 1.00 32.29  ? 169 ARG D CB    1 
ATOM   3301 C CG    . ARG B 1 169 ? 137.951 113.898 152.217 1.00 34.34  ? 169 ARG D CG    1 
ATOM   3302 C CD    . ARG B 1 169 ? 136.593 113.404 152.655 1.00 36.09  ? 169 ARG D CD    1 
ATOM   3303 N NE    . ARG B 1 169 ? 135.506 114.174 152.070 1.00 34.50  ? 169 ARG D NE    1 
ATOM   3304 C CZ    . ARG B 1 169 ? 134.239 113.790 152.072 1.00 39.97  ? 169 ARG D CZ    1 
ATOM   3305 N NH1   . ARG B 1 169 ? 133.868 112.637 152.602 1.00 40.66  ? 169 ARG D NH1   1 
ATOM   3306 N NH2   . ARG B 1 169 ? 133.321 114.581 151.527 1.00 44.42  ? 169 ARG D NH2   1 
ATOM   3307 N N     . TYR B 1 170 ? 141.614 111.293 152.832 1.00 36.28  ? 170 TYR D N     1 
ATOM   3308 C CA    . TYR B 1 170 ? 142.549 110.438 153.556 1.00 36.20  ? 170 TYR D CA    1 
ATOM   3309 C C     . TYR B 1 170 ? 143.972 110.969 153.452 1.00 45.06  ? 170 TYR D C     1 
ATOM   3310 O O     . TYR B 1 170 ? 144.726 110.942 154.432 1.00 50.67  ? 170 TYR D O     1 
ATOM   3311 C CB    . TYR B 1 170 ? 142.467 109.013 153.017 1.00 37.02  ? 170 TYR D CB    1 
ATOM   3312 C CG    . TYR B 1 170 ? 143.350 108.023 153.736 1.00 41.35  ? 170 TYR D CG    1 
ATOM   3313 C CD1   . TYR B 1 170 ? 144.653 107.801 153.324 1.00 47.31  ? 170 TYR D CD1   1 
ATOM   3314 C CD2   . TYR B 1 170 ? 142.876 107.303 154.819 1.00 46.33  ? 170 TYR D CD2   1 
ATOM   3315 C CE1   . TYR B 1 170 ? 145.462 106.893 153.975 1.00 53.33  ? 170 TYR D CE1   1 
ATOM   3316 C CE2   . TYR B 1 170 ? 143.678 106.391 155.475 1.00 52.59  ? 170 TYR D CE2   1 
ATOM   3317 C CZ    . TYR B 1 170 ? 144.970 106.191 155.050 1.00 56.91  ? 170 TYR D CZ    1 
ATOM   3318 O OH    . TYR B 1 170 ? 145.774 105.285 155.701 1.00 61.48  ? 170 TYR D OH    1 
ATOM   3319 N N     . VAL B 1 171 ? 144.365 111.445 152.270 1.00 46.12  ? 171 VAL D N     1 
ATOM   3320 C CA    . VAL B 1 171 ? 145.669 112.083 152.123 1.00 43.49  ? 171 VAL D CA    1 
ATOM   3321 C C     . VAL B 1 171 ? 145.741 113.337 152.980 1.00 43.82  ? 171 VAL D C     1 
ATOM   3322 O O     . VAL B 1 171 ? 146.735 113.575 153.676 1.00 49.41  ? 171 VAL D O     1 
ATOM   3323 C CB    . VAL B 1 171 ? 145.941 112.394 150.639 1.00 44.16  ? 171 VAL D CB    1 
ATOM   3324 C CG1   . VAL B 1 171 ? 146.842 113.610 150.491 1.00 45.01  ? 171 VAL D CG1   1 
ATOM   3325 C CG2   . VAL B 1 171 ? 146.559 111.189 149.955 1.00 46.78  ? 171 VAL D CG2   1 
ATOM   3326 N N     . SER B 1 172 ? 144.689 114.157 152.950 1.00 42.88  ? 172 SER D N     1 
ATOM   3327 C CA    . SER B 1 172 ? 144.699 115.400 153.710 1.00 44.29  ? 172 SER D CA    1 
ATOM   3328 C C     . SER B 1 172 ? 144.802 115.163 155.207 1.00 48.33  ? 172 SER D C     1 
ATOM   3329 O O     . SER B 1 172 ? 145.167 116.086 155.942 1.00 52.23  ? 172 SER D O     1 
ATOM   3330 C CB    . SER B 1 172 ? 143.443 116.213 153.408 1.00 46.19  ? 172 SER D CB    1 
ATOM   3331 O OG    . SER B 1 172 ? 143.516 116.788 152.118 1.00 54.44  ? 172 SER D OG    1 
ATOM   3332 N N     . LEU B 1 173 ? 144.488 113.957 155.683 1.00 50.54  ? 173 LEU D N     1 
ATOM   3333 C CA    . LEU B 1 173 ? 144.572 113.712 157.121 1.00 49.77  ? 173 LEU D CA    1 
ATOM   3334 C C     . LEU B 1 173 ? 145.988 113.925 157.645 1.00 53.90  ? 173 LEU D C     1 
ATOM   3335 O O     . LEU B 1 173 ? 146.177 114.531 158.706 1.00 58.84  ? 173 LEU D O     1 
ATOM   3336 C CB    . LEU B 1 173 ? 144.097 112.298 157.458 1.00 44.58  ? 173 LEU D CB    1 
ATOM   3337 C CG    . LEU B 1 173 ? 142.604 112.092 157.714 1.00 43.52  ? 173 LEU D CG    1 
ATOM   3338 C CD1   . LEU B 1 173 ? 142.367 110.683 158.201 1.00 50.70  ? 173 LEU D CD1   1 
ATOM   3339 C CD2   . LEU B 1 173 ? 142.044 113.093 158.703 1.00 45.09  ? 173 LEU D CD2   1 
ATOM   3340 N N     . VAL B 1 174 ? 146.998 113.437 156.924 1.00 58.44  ? 174 VAL D N     1 
ATOM   3341 C CA    . VAL B 1 174 ? 148.369 113.472 157.426 1.00 62.56  ? 174 VAL D CA    1 
ATOM   3342 C C     . VAL B 1 174 ? 149.307 114.122 156.416 1.00 67.07  ? 174 VAL D C     1 
ATOM   3343 O O     . VAL B 1 174 ? 150.528 113.948 156.494 1.00 67.74  ? 174 VAL D O     1 
ATOM   3344 C CB    . VAL B 1 174 ? 148.860 112.056 157.779 1.00 61.95  ? 174 VAL D CB    1 
ATOM   3345 C CG1   . VAL B 1 174 ? 147.859 111.355 158.686 1.00 59.49  ? 174 VAL D CG1   1 
ATOM   3346 C CG2   . VAL B 1 174 ? 149.110 111.248 156.513 1.00 60.06  ? 174 VAL D CG2   1 
ATOM   3347 N N     . ALA B 1 175 ? 148.755 114.879 155.469 1.00 71.11  ? 175 ALA D N     1 
ATOM   3348 C CA    . ALA B 1 175 ? 149.573 115.636 154.521 1.00 68.21  ? 175 ALA D CA    1 
ATOM   3349 C C     . ALA B 1 175 ? 148.773 116.871 154.118 1.00 69.56  ? 175 ALA D C     1 
ATOM   3350 O O     . ALA B 1 175 ? 147.880 116.787 153.272 1.00 73.03  ? 175 ALA D O     1 
ATOM   3351 C CB    . ALA B 1 175 ? 149.947 114.795 153.310 1.00 64.06  ? 175 ALA D CB    1 
ATOM   3352 N N     . LEU B 1 176 ? 149.104 118.006 154.722 1.00 72.33  ? 176 LEU D N     1 
ATOM   3353 C CA    . LEU B 1 176 ? 148.396 119.240 154.422 1.00 76.82  ? 176 LEU D CA    1 
ATOM   3354 C C     . LEU B 1 176 ? 148.609 119.641 152.968 1.00 82.69  ? 176 LEU D C     1 
ATOM   3355 O O     . LEU B 1 176 ? 149.660 119.384 152.374 1.00 84.53  ? 176 LEU D O     1 
ATOM   3356 C CB    . LEU B 1 176 ? 148.871 120.360 155.346 1.00 83.70  ? 176 LEU D CB    1 
ATOM   3357 C CG    . LEU B 1 176 ? 148.616 120.135 156.836 1.00 85.54  ? 176 LEU D CG    1 
ATOM   3358 C CD1   . LEU B 1 176 ? 149.344 121.187 157.656 1.00 86.21  ? 176 LEU D CD1   1 
ATOM   3359 C CD2   . LEU B 1 176 ? 147.122 120.144 157.123 1.00 80.71  ? 176 LEU D CD2   1 
ATOM   3360 N N     . ASP B 1 177 ? 147.593 120.279 152.395 1.00 83.75  ? 177 ASP D N     1 
ATOM   3361 C CA    . ASP B 1 177 ? 147.664 120.795 151.034 1.00 85.12  ? 177 ASP D CA    1 
ATOM   3362 C C     . ASP B 1 177 ? 148.150 122.239 151.080 1.00 91.34  ? 177 ASP D C     1 
ATOM   3363 O O     . ASP B 1 177 ? 147.541 123.084 151.745 1.00 90.53  ? 177 ASP D O     1 
ATOM   3364 C CB    . ASP B 1 177 ? 146.299 120.701 150.353 1.00 80.93  ? 177 ASP D CB    1 
ATOM   3365 C CG    . ASP B 1 177 ? 146.398 120.747 148.842 1.00 86.61  ? 177 ASP D CG    1 
ATOM   3366 O OD1   . ASP B 1 177 ? 147.510 120.977 148.322 1.00 87.77  ? 177 ASP D OD1   1 
ATOM   3367 O OD2   . ASP B 1 177 ? 145.362 120.551 148.171 1.00 87.32  ? 177 ASP D OD2   1 
ATOM   3368 N N     . GLU B 1 178 ? 149.246 122.520 150.372 1.00 89.08  ? 178 GLU D N     1 
ATOM   3369 C CA    . GLU B 1 178 ? 149.825 123.859 150.412 1.00 91.40  ? 178 GLU D CA    1 
ATOM   3370 C C     . GLU B 1 178 ? 148.855 124.906 149.878 1.00 89.09  ? 178 GLU D C     1 
ATOM   3371 O O     . GLU B 1 178 ? 148.902 126.067 150.299 1.00 89.43  ? 178 GLU D O     1 
ATOM   3372 C CB    . GLU B 1 178 ? 151.130 123.886 149.614 1.00 91.36  ? 178 GLU D CB    1 
ATOM   3373 C CG    . GLU B 1 178 ? 151.857 125.227 149.635 1.00 90.58  ? 178 GLU D CG    1 
ATOM   3374 C CD    . GLU B 1 178 ? 152.587 125.475 150.940 1.00 94.46  ? 178 GLU D CD    1 
ATOM   3375 O OE1   . GLU B 1 178 ? 152.663 124.545 151.769 1.00 96.81  ? 178 GLU D OE1   1 
ATOM   3376 O OE2   . GLU B 1 178 ? 153.084 126.604 151.136 1.00 95.43  ? 178 GLU D OE2   1 
ATOM   3377 N N     . ARG B 1 179 ? 147.966 124.517 148.963 1.00 85.29  ? 179 ARG D N     1 
ATOM   3378 C CA    . ARG B 1 179 ? 147.046 125.478 148.367 1.00 83.09  ? 179 ARG D CA    1 
ATOM   3379 C C     . ARG B 1 179 ? 146.060 126.041 149.380 1.00 85.05  ? 179 ARG D C     1 
ATOM   3380 O O     . ARG B 1 179 ? 145.401 127.046 149.093 1.00 84.31  ? 179 ARG D O     1 
ATOM   3381 C CB    . ARG B 1 179 ? 146.288 124.821 147.213 1.00 81.90  ? 179 ARG D CB    1 
ATOM   3382 C CG    . ARG B 1 179 ? 145.346 125.757 146.471 1.00 77.78  ? 179 ARG D CG    1 
ATOM   3383 C CD    . ARG B 1 179 ? 144.785 125.118 145.207 1.00 75.61  ? 179 ARG D CD    1 
ATOM   3384 N NE    . ARG B 1 179 ? 144.614 123.675 145.340 1.00 77.20  ? 179 ARG D NE    1 
ATOM   3385 C CZ    . ARG B 1 179 ? 145.505 122.767 144.964 1.00 78.76  ? 179 ARG D CZ    1 
ATOM   3386 N NH1   . ARG B 1 179 ? 146.660 123.112 144.419 1.00 83.75  ? 179 ARG D NH1   1 
ATOM   3387 N NH2   . ARG B 1 179 ? 145.231 121.478 145.143 1.00 73.08  ? 179 ARG D NH2   1 
ATOM   3388 N N     . ILE B 1 180 ? 145.944 125.424 150.552 1.00 87.21  ? 180 ILE D N     1 
ATOM   3389 C CA    . ILE B 1 180 ? 144.994 125.844 151.575 1.00 88.43  ? 180 ILE D CA    1 
ATOM   3390 C C     . ILE B 1 180 ? 145.749 126.642 152.629 1.00 88.60  ? 180 ILE D C     1 
ATOM   3391 O O     . ILE B 1 180 ? 146.669 126.123 153.274 1.00 85.20  ? 180 ILE D O     1 
ATOM   3392 C CB    . ILE B 1 180 ? 144.279 124.637 152.202 1.00 85.28  ? 180 ILE D CB    1 
ATOM   3393 C CG1   . ILE B 1 180 ? 143.756 123.709 151.102 1.00 83.46  ? 180 ILE D CG1   1 
ATOM   3394 C CG2   . ILE B 1 180 ? 143.135 125.104 153.090 1.00 82.70  ? 180 ILE D CG2   1 
ATOM   3395 C CD1   . ILE B 1 180 ? 142.997 122.509 151.615 1.00 82.13  ? 180 ILE D CD1   1 
ATOM   3396 N N     . GLN B 1 181 ? 145.362 127.907 152.802 1.00 90.39  ? 181 GLN D N     1 
ATOM   3397 C CA    . GLN B 1 181 ? 145.957 128.762 153.823 1.00 91.39  ? 181 GLN D CA    1 
ATOM   3398 C C     . GLN B 1 181 ? 144.941 129.561 154.624 1.00 90.39  ? 181 GLN D C     1 
ATOM   3399 O O     . GLN B 1 181 ? 145.318 130.132 155.651 1.00 87.54  ? 181 GLN D O     1 
ATOM   3400 C CB    . GLN B 1 181 ? 146.957 129.736 153.183 1.00 90.10  ? 181 GLN D CB    1 
ATOM   3401 C CG    . GLN B 1 181 ? 148.079 129.052 152.421 1.00 88.17  ? 181 GLN D CG    1 
ATOM   3402 C CD    . GLN B 1 181 ? 148.982 128.238 153.323 1.00 89.14  ? 181 GLN D CD    1 
ATOM   3403 O OE1   . GLN B 1 181 ? 149.271 128.635 154.451 1.00 88.61  ? 181 GLN D OE1   1 
ATOM   3404 N NE2   . GLN B 1 181 ? 149.428 127.089 152.833 1.00 90.42  ? 181 GLN D NE2   1 
ATOM   3405 N N     . THR B 1 182 ? 143.681 129.627 154.202 1.00 89.11  ? 182 THR D N     1 
ATOM   3406 C CA    . THR B 1 182 ? 142.649 130.353 154.925 1.00 87.34  ? 182 THR D CA    1 
ATOM   3407 C C     . THR B 1 182 ? 141.357 129.553 154.865 1.00 87.59  ? 182 THR D C     1 
ATOM   3408 O O     . THR B 1 182 ? 141.215 128.628 154.062 1.00 90.25  ? 182 THR D O     1 
ATOM   3409 C CB    . THR B 1 182 ? 142.424 131.754 154.344 1.00 89.48  ? 182 THR D CB    1 
ATOM   3410 O OG1   . THR B 1 182 ? 141.842 131.647 153.039 1.00 83.07  ? 182 THR D OG1   1 
ATOM   3411 C CG2   . THR B 1 182 ? 143.739 132.511 154.247 1.00 89.17  ? 182 THR D CG2   1 
ATOM   3412 N N     . LEU B 1 183 ? 140.410 129.915 155.734 1.00 82.76  ? 183 LEU D N     1 
ATOM   3413 C CA    . LEU B 1 183 ? 139.127 129.220 155.743 1.00 80.77  ? 183 LEU D CA    1 
ATOM   3414 C C     . LEU B 1 183 ? 138.445 129.293 154.385 1.00 84.35  ? 183 LEU D C     1 
ATOM   3415 O O     . LEU B 1 183 ? 137.748 128.352 153.989 1.00 82.64  ? 183 LEU D O     1 
ATOM   3416 C CB    . LEU B 1 183 ? 138.213 129.802 156.821 1.00 79.24  ? 183 LEU D CB    1 
ATOM   3417 C CG    . LEU B 1 183 ? 138.590 129.512 158.275 1.00 79.79  ? 183 LEU D CG    1 
ATOM   3418 C CD1   . LEU B 1 183 ? 137.617 130.203 159.216 1.00 76.93  ? 183 LEU D CD1   1 
ATOM   3419 C CD2   . LEU B 1 183 ? 138.626 128.017 158.544 1.00 81.09  ? 183 LEU D CD2   1 
ATOM   3420 N N     . GLU B 1 184 ? 138.631 130.394 153.654 1.00 87.21  ? 184 GLU D N     1 
ATOM   3421 C CA    . GLU B 1 184 ? 138.033 130.496 152.328 1.00 88.18  ? 184 GLU D CA    1 
ATOM   3422 C C     . GLU B 1 184 ? 138.588 129.429 151.394 1.00 82.96  ? 184 GLU D C     1 
ATOM   3423 O O     . GLU B 1 184 ? 137.832 128.782 150.660 1.00 79.41  ? 184 GLU D O     1 
ATOM   3424 C CB    . GLU B 1 184 ? 138.271 131.889 151.749 1.00 92.23  ? 184 GLU D CB    1 
ATOM   3425 C CG    . GLU B 1 184 ? 137.117 132.403 150.906 1.00 90.41  ? 184 GLU D CG    1 
ATOM   3426 C CD    . GLU B 1 184 ? 136.975 131.652 149.599 1.00 89.33  ? 184 GLU D CD    1 
ATOM   3427 O OE1   . GLU B 1 184 ? 137.980 131.083 149.127 1.00 87.41  ? 184 GLU D OE1   1 
ATOM   3428 O OE2   . GLU B 1 184 ? 135.855 131.626 149.047 1.00 93.19  ? 184 GLU D OE2   1 
ATOM   3429 N N     . ASP B 1 185 ? 139.907 129.227 151.405 1.00 83.70  ? 185 ASP D N     1 
ATOM   3430 C CA    . ASP B 1 185 ? 140.497 128.194 150.561 1.00 82.96  ? 185 ASP D CA    1 
ATOM   3431 C C     . ASP B 1 185 ? 140.026 126.807 150.979 1.00 78.75  ? 185 ASP D C     1 
ATOM   3432 O O     . ASP B 1 185 ? 139.694 125.974 150.129 1.00 81.22  ? 185 ASP D O     1 
ATOM   3433 C CB    . ASP B 1 185 ? 142.022 128.275 150.614 1.00 85.06  ? 185 ASP D CB    1 
ATOM   3434 C CG    . ASP B 1 185 ? 142.542 129.665 150.307 1.00 90.49  ? 185 ASP D CG    1 
ATOM   3435 O OD1   . ASP B 1 185 ? 141.858 130.409 149.573 1.00 92.70  ? 185 ASP D OD1   1 
ATOM   3436 O OD2   . ASP B 1 185 ? 143.639 130.010 150.796 1.00 89.68  ? 185 ASP D OD2   1 
ATOM   3437 N N     . ALA B 1 186 ? 139.989 126.542 152.285 1.00 73.75  ? 186 ALA D N     1 
ATOM   3438 C CA    . ALA B 1 186 ? 139.547 125.241 152.769 1.00 71.70  ? 186 ALA D CA    1 
ATOM   3439 C C     . ALA B 1 186 ? 138.066 125.000 152.511 1.00 73.32  ? 186 ALA D C     1 
ATOM   3440 O O     . ALA B 1 186 ? 137.627 123.846 152.532 1.00 70.22  ? 186 ALA D O     1 
ATOM   3441 C CB    . ALA B 1 186 ? 139.835 125.114 154.265 1.00 71.95  ? 186 ALA D CB    1 
ATOM   3442 N N     . GLN B 1 187 ? 137.289 126.057 152.271 1.00 75.76  ? 187 GLN D N     1 
ATOM   3443 C CA    . GLN B 1 187 ? 135.857 125.893 152.057 1.00 74.31  ? 187 GLN D CA    1 
ATOM   3444 C C     . GLN B 1 187 ? 135.542 125.074 150.813 1.00 72.58  ? 187 GLN D C     1 
ATOM   3445 O O     . GLN B 1 187 ? 134.457 124.488 150.733 1.00 72.75  ? 187 GLN D O     1 
ATOM   3446 C CB    . GLN B 1 187 ? 135.186 127.262 151.951 1.00 78.15  ? 187 GLN D CB    1 
ATOM   3447 C CG    . GLN B 1 187 ? 133.687 127.204 151.708 1.00 79.20  ? 187 GLN D CG    1 
ATOM   3448 C CD    . GLN B 1 187 ? 133.050 128.575 151.714 1.00 77.50  ? 187 GLN D CD    1 
ATOM   3449 O OE1   . GLN B 1 187 ? 133.732 129.586 151.869 1.00 80.81  ? 187 GLN D OE1   1 
ATOM   3450 N NE2   . GLN B 1 187 ? 131.734 128.617 151.548 1.00 71.71  ? 187 GLN D NE2   1 
ATOM   3451 N N     . TRP B 1 188 ? 136.455 125.019 149.844 1.00 71.52  ? 188 TRP D N     1 
ATOM   3452 C CA    . TRP B 1 188 ? 136.204 124.360 148.568 1.00 67.47  ? 188 TRP D CA    1 
ATOM   3453 C C     . TRP B 1 188 ? 136.946 123.036 148.440 1.00 64.45  ? 188 TRP D C     1 
ATOM   3454 O O     . TRP B 1 188 ? 137.084 122.513 147.331 1.00 66.42  ? 188 TRP D O     1 
ATOM   3455 C CB    . TRP B 1 188 ? 136.583 125.289 147.418 1.00 71.97  ? 188 TRP D CB    1 
ATOM   3456 C CG    . TRP B 1 188 ? 135.815 126.567 147.423 1.00 76.01  ? 188 TRP D CG    1 
ATOM   3457 C CD1   . TRP B 1 188 ? 136.316 127.822 147.597 1.00 77.37  ? 188 TRP D CD1   1 
ATOM   3458 C CD2   . TRP B 1 188 ? 134.402 126.719 147.249 1.00 75.26  ? 188 TRP D CD2   1 
ATOM   3459 N NE1   . TRP B 1 188 ? 135.303 128.747 147.543 1.00 78.75  ? 188 TRP D NE1   1 
ATOM   3460 C CE2   . TRP B 1 188 ? 134.118 128.095 147.328 1.00 75.99  ? 188 TRP D CE2   1 
ATOM   3461 C CE3   . TRP B 1 188 ? 133.350 125.825 147.032 1.00 74.98  ? 188 TRP D CE3   1 
ATOM   3462 C CZ2   . TRP B 1 188 ? 132.827 128.598 147.199 1.00 78.09  ? 188 TRP D CZ2   1 
ATOM   3463 C CZ3   . TRP B 1 188 ? 132.071 126.327 146.903 1.00 77.54  ? 188 TRP D CZ3   1 
ATOM   3464 C CH2   . TRP B 1 188 ? 131.820 127.700 146.988 1.00 81.67  ? 188 TRP D CH2   1 
ATOM   3465 N N     . PHE B 1 189 ? 137.429 122.487 149.548 1.00 60.78  ? 189 PHE D N     1 
ATOM   3466 C CA    . PHE B 1 189 ? 138.105 121.201 149.502 1.00 59.79  ? 189 PHE D CA    1 
ATOM   3467 C C     . PHE B 1 189 ? 137.107 120.103 149.138 1.00 59.60  ? 189 PHE D C     1 
ATOM   3468 O O     . PHE B 1 189 ? 135.947 120.157 149.557 1.00 62.73  ? 189 PHE D O     1 
ATOM   3469 C CB    . PHE B 1 189 ? 138.748 120.898 150.853 1.00 59.42  ? 189 PHE D CB    1 
ATOM   3470 C CG    . PHE B 1 189 ? 139.461 119.581 150.908 1.00 56.30  ? 189 PHE D CG    1 
ATOM   3471 C CD1   . PHE B 1 189 ? 138.771 118.412 151.168 1.00 51.69  ? 189 PHE D CD1   1 
ATOM   3472 C CD2   . PHE B 1 189 ? 140.827 119.514 150.710 1.00 54.27  ? 189 PHE D CD2   1 
ATOM   3473 C CE1   . PHE B 1 189 ? 139.427 117.205 151.223 1.00 47.87  ? 189 PHE D CE1   1 
ATOM   3474 C CE2   . PHE B 1 189 ? 141.487 118.310 150.764 1.00 47.23  ? 189 PHE D CE2   1 
ATOM   3475 C CZ    . PHE B 1 189 ? 140.788 117.153 151.021 1.00 47.92  ? 189 PHE D CZ    1 
ATOM   3476 N N     . PRO B 1 190 ? 137.519 119.091 148.355 1.00 56.13  ? 190 PRO D N     1 
ATOM   3477 C CA    . PRO B 1 190 ? 138.818 118.911 147.698 1.00 55.77  ? 190 PRO D CA    1 
ATOM   3478 C C     . PRO B 1 190 ? 138.931 119.678 146.386 1.00 60.17  ? 190 PRO D C     1 
ATOM   3479 O O     . PRO B 1 190 ? 137.915 120.069 145.814 1.00 62.54  ? 190 PRO D O     1 
ATOM   3480 C CB    . PRO B 1 190 ? 138.870 117.406 147.453 1.00 51.78  ? 190 PRO D CB    1 
ATOM   3481 C CG    . PRO B 1 190 ? 137.460 117.027 147.247 1.00 52.74  ? 190 PRO D CG    1 
ATOM   3482 C CD    . PRO B 1 190 ? 136.639 117.932 148.129 1.00 55.60  ? 190 PRO D CD    1 
ATOM   3483 N N     . TYR B 1 191 ? 140.159 119.885 145.920 1.00 59.64  ? 191 TYR D N     1 
ATOM   3484 C CA    . TYR B 1 191 ? 140.422 120.568 144.656 1.00 64.94  ? 191 TYR D CA    1 
ATOM   3485 C C     . TYR B 1 191 ? 140.677 119.507 143.591 1.00 66.55  ? 191 TYR D C     1 
ATOM   3486 O O     . TYR B 1 191 ? 141.754 118.908 143.541 1.00 65.76  ? 191 TYR D O     1 
ATOM   3487 C CB    . TYR B 1 191 ? 141.603 121.520 144.798 1.00 68.51  ? 191 TYR D CB    1 
ATOM   3488 C CG    . TYR B 1 191 ? 141.300 122.737 145.639 1.00 72.32  ? 191 TYR D CG    1 
ATOM   3489 C CD1   . TYR B 1 191 ? 140.787 123.890 145.063 1.00 71.11  ? 191 TYR D CD1   1 
ATOM   3490 C CD2   . TYR B 1 191 ? 141.522 122.733 147.009 1.00 73.24  ? 191 TYR D CD2   1 
ATOM   3491 C CE1   . TYR B 1 191 ? 140.506 125.004 145.824 1.00 75.06  ? 191 TYR D CE1   1 
ATOM   3492 C CE2   . TYR B 1 191 ? 141.245 123.845 147.779 1.00 73.33  ? 191 TYR D CE2   1 
ATOM   3493 C CZ    . TYR B 1 191 ? 140.736 124.976 147.180 1.00 74.92  ? 191 TYR D CZ    1 
ATOM   3494 O OH    . TYR B 1 191 ? 140.457 126.088 147.938 1.00 73.19  ? 191 TYR D OH    1 
ATOM   3495 N N     . LEU B 1 192 ? 139.687 119.281 142.733 1.00 63.06  ? 192 LEU D N     1 
ATOM   3496 C CA    . LEU B 1 192 ? 139.749 118.254 141.705 1.00 61.63  ? 192 LEU D CA    1 
ATOM   3497 C C     . LEU B 1 192 ? 139.397 118.848 140.346 1.00 66.16  ? 192 LEU D C     1 
ATOM   3498 O O     . LEU B 1 192 ? 138.946 119.990 140.234 1.00 67.41  ? 192 LEU D O     1 
ATOM   3499 C CB    . LEU B 1 192 ? 138.807 117.091 142.038 1.00 59.69  ? 192 LEU D CB    1 
ATOM   3500 C CG    . LEU B 1 192 ? 138.989 116.467 143.422 1.00 55.79  ? 192 LEU D CG    1 
ATOM   3501 C CD1   . LEU B 1 192 ? 137.945 115.396 143.662 1.00 53.38  ? 192 LEU D CD1   1 
ATOM   3502 C CD2   . LEU B 1 192 ? 140.386 115.892 143.581 1.00 55.20  ? 192 LEU D CD2   1 
ATOM   3503 N N     . SER B 1 193 ? 139.603 118.044 139.306 1.00 66.89  ? 193 SER D N     1 
ATOM   3504 C CA    . SER B 1 193 ? 139.439 118.509 137.939 1.00 70.07  ? 193 SER D CA    1 
ATOM   3505 C C     . SER B 1 193 ? 137.965 118.749 137.620 1.00 69.88  ? 193 SER D C     1 
ATOM   3506 O O     . SER B 1 193 ? 137.067 118.454 138.412 1.00 72.16  ? 193 SER D O     1 
ATOM   3507 C CB    . SER B 1 193 ? 140.029 117.498 136.959 1.00 71.77  ? 193 SER D CB    1 
ATOM   3508 O OG    . SER B 1 193 ? 139.466 116.214 137.157 1.00 67.73  ? 193 SER D OG    1 
ATOM   3509 N N     . GLY B 1 194 ? 137.724 119.300 136.429 1.00 71.80  ? 194 GLY D N     1 
ATOM   3510 C CA    . GLY B 1 194 ? 136.360 119.581 136.014 1.00 75.00  ? 194 GLY D CA    1 
ATOM   3511 C C     . GLY B 1 194 ? 135.531 118.327 135.809 1.00 76.63  ? 194 GLY D C     1 
ATOM   3512 O O     . GLY B 1 194 ? 134.326 118.321 136.072 1.00 79.53  ? 194 GLY D O     1 
ATOM   3513 N N     . ASP B 1 195 ? 136.159 117.252 135.327 1.00 70.45  ? 195 ASP D N     1 
ATOM   3514 C CA    . ASP B 1 195 ? 135.427 116.006 135.125 1.00 67.78  ? 195 ASP D CA    1 
ATOM   3515 C C     . ASP B 1 195 ? 134.885 115.475 136.444 1.00 68.65  ? 195 ASP D C     1 
ATOM   3516 O O     . ASP B 1 195 ? 133.748 114.989 136.511 1.00 66.45  ? 195 ASP D O     1 
ATOM   3517 C CB    . ASP B 1 195 ? 136.328 114.966 134.463 1.00 67.15  ? 195 ASP D CB    1 
ATOM   3518 C CG    . ASP B 1 195 ? 137.110 115.529 133.295 1.00 78.41  ? 195 ASP D CG    1 
ATOM   3519 O OD1   . ASP B 1 195 ? 137.998 116.375 133.530 1.00 81.36  ? 195 ASP D OD1   1 
ATOM   3520 O OD2   . ASP B 1 195 ? 136.837 115.128 132.144 1.00 79.36  ? 195 ASP D OD2   1 
ATOM   3521 N N     . SER B 1 196 ? 135.686 115.560 137.508 1.00 68.42  ? 196 SER D N     1 
ATOM   3522 C CA    . SER B 1 196 ? 135.225 115.106 138.813 1.00 60.39  ? 196 SER D CA    1 
ATOM   3523 C C     . SER B 1 196 ? 134.008 115.897 139.267 1.00 60.07  ? 196 SER D C     1 
ATOM   3524 O O     . SER B 1 196 ? 133.039 115.321 139.773 1.00 65.98  ? 196 SER D O     1 
ATOM   3525 C CB    . SER B 1 196 ? 136.354 115.223 139.835 1.00 61.81  ? 196 SER D CB    1 
ATOM   3526 O OG    . SER B 1 196 ? 137.363 114.259 139.592 1.00 59.62  ? 196 SER D OG    1 
ATOM   3527 N N     . TYR B 1 197 ? 134.032 117.219 139.091 1.00 61.11  ? 197 TYR D N     1 
ATOM   3528 C CA    . TYR B 1 197 ? 132.876 118.018 139.478 1.00 65.55  ? 197 TYR D CA    1 
ATOM   3529 C C     . TYR B 1 197 ? 131.660 117.667 138.634 1.00 67.62  ? 197 TYR D C     1 
ATOM   3530 O O     . TYR B 1 197 ? 130.535 117.614 139.143 1.00 71.72  ? 197 TYR D O     1 
ATOM   3531 C CB    . TYR B 1 197 ? 133.187 119.506 139.358 1.00 71.41  ? 197 TYR D CB    1 
ATOM   3532 C CG    . TYR B 1 197 ? 132.039 120.373 139.810 1.00 73.52  ? 197 TYR D CG    1 
ATOM   3533 C CD1   . TYR B 1 197 ? 131.840 120.646 141.155 1.00 74.52  ? 197 TYR D CD1   1 
ATOM   3534 C CD2   . TYR B 1 197 ? 131.142 120.900 138.895 1.00 73.96  ? 197 TYR D CD2   1 
ATOM   3535 C CE1   . TYR B 1 197 ? 130.787 121.431 141.573 1.00 80.00  ? 197 TYR D CE1   1 
ATOM   3536 C CE2   . TYR B 1 197 ? 130.087 121.686 139.303 1.00 75.45  ? 197 TYR D CE2   1 
ATOM   3537 C CZ    . TYR B 1 197 ? 129.913 121.948 140.643 1.00 81.76  ? 197 TYR D CZ    1 
ATOM   3538 O OH    . TYR B 1 197 ? 128.859 122.731 141.054 1.00 87.83  ? 197 TYR D OH    1 
ATOM   3539 N N     . ARG B 1 198 ? 131.863 117.434 137.337 1.00 69.85  ? 198 ARG D N     1 
ATOM   3540 C CA    . ARG B 1 198 ? 130.743 117.081 136.471 1.00 77.28  ? 198 ARG D CA    1 
ATOM   3541 C C     . ARG B 1 198 ? 130.107 115.766 136.904 1.00 72.74  ? 198 ARG D C     1 
ATOM   3542 O O     . ARG B 1 198 ? 128.877 115.639 136.924 1.00 74.47  ? 198 ARG D O     1 
ATOM   3543 C CB    . ARG B 1 198 ? 131.210 116.994 135.018 1.00 83.80  ? 198 ARG D CB    1 
ATOM   3544 C CG    . ARG B 1 198 ? 131.213 118.326 134.289 1.00 89.61  ? 198 ARG D CG    1 
ATOM   3545 C CD    . ARG B 1 198 ? 129.820 118.721 133.830 1.00 97.35  ? 198 ARG D CD    1 
ATOM   3546 N NE    . ARG B 1 198 ? 129.862 119.700 132.750 1.00 108.96 ? 198 ARG D NE    1 
ATOM   3547 C CZ    . ARG B 1 198 ? 128.791 120.204 132.150 1.00 114.82 ? 198 ARG D CZ    1 
ATOM   3548 N NH1   . ARG B 1 198 ? 127.568 119.838 132.495 1.00 117.90 ? 198 ARG D NH1   1 
ATOM   3549 N NH2   . ARG B 1 198 ? 128.953 121.096 131.177 1.00 114.19 ? 198 ARG D NH2   1 
ATOM   3550 N N     . ALA B 1 199 ? 130.928 114.773 137.250 1.00 65.97  ? 199 ALA D N     1 
ATOM   3551 C CA    . ALA B 1 199 ? 130.388 113.467 137.610 1.00 62.36  ? 199 ALA D CA    1 
ATOM   3552 C C     . ALA B 1 199 ? 129.646 113.516 138.942 1.00 64.54  ? 199 ALA D C     1 
ATOM   3553 O O     . ALA B 1 199 ? 128.514 113.033 139.050 1.00 64.04  ? 199 ALA D O     1 
ATOM   3554 C CB    . ALA B 1 199 ? 131.513 112.437 137.663 1.00 60.24  ? 199 ALA D CB    1 
ATOM   3555 N N     . CYS B 1 200 ? 130.266 114.099 139.968 1.00 64.62  ? 200 CYS D N     1 
ATOM   3556 C CA    . CYS B 1 200 ? 129.716 114.126 141.324 1.00 56.46  ? 200 CYS D CA    1 
ATOM   3557 C C     . CYS B 1 200 ? 129.771 115.552 141.854 1.00 59.74  ? 200 CYS D C     1 
ATOM   3558 O O     . CYS B 1 200 ? 130.653 115.896 142.652 1.00 58.73  ? 200 CYS D O     1 
ATOM   3559 C CB    . CYS B 1 200 ? 130.476 113.172 142.244 1.00 52.03  ? 200 CYS D CB    1 
ATOM   3560 S SG    . CYS B 1 200 ? 130.103 111.430 141.967 1.00 69.57  ? 200 CYS D SG    1 
ATOM   3561 N N     . PRO B 1 201 ? 128.842 116.412 141.432 1.00 63.81  ? 201 PRO D N     1 
ATOM   3562 C CA    . PRO B 1 201 ? 128.887 117.810 141.890 1.00 68.62  ? 201 PRO D CA    1 
ATOM   3563 C C     . PRO B 1 201 ? 128.778 117.967 143.396 1.00 69.61  ? 201 PRO D C     1 
ATOM   3564 O O     . PRO B 1 201 ? 129.372 118.896 143.955 1.00 70.35  ? 201 PRO D O     1 
ATOM   3565 C CB    . PRO B 1 201 ? 127.696 118.456 141.167 1.00 67.32  ? 201 PRO D CB    1 
ATOM   3566 C CG    . PRO B 1 201 ? 126.828 117.330 140.738 1.00 64.69  ? 201 PRO D CG    1 
ATOM   3567 C CD    . PRO B 1 201 ? 127.726 116.165 140.507 1.00 63.29  ? 201 PRO D CD    1 
ATOM   3568 N N     . GLY B 1 202 ? 128.039 117.092 144.074 1.00 68.57  ? 202 GLY D N     1 
ATOM   3569 C CA    . GLY B 1 202 ? 127.791 117.267 145.493 1.00 68.33  ? 202 GLY D CA    1 
ATOM   3570 C C     . GLY B 1 202 ? 128.938 116.899 146.408 1.00 60.72  ? 202 GLY D C     1 
ATOM   3571 O O     . GLY B 1 202 ? 128.883 117.222 147.598 1.00 59.14  ? 202 GLY D O     1 
ATOM   3572 N N     . LEU B 1 203 ? 129.973 116.236 145.889 1.00 60.57  ? 203 LEU D N     1 
ATOM   3573 C CA    . LEU B 1 203 ? 131.097 115.792 146.701 1.00 61.08  ? 203 LEU D CA    1 
ATOM   3574 C C     . LEU B 1 203 ? 132.424 116.424 146.320 1.00 59.51  ? 203 LEU D C     1 
ATOM   3575 O O     . LEU B 1 203 ? 133.352 116.397 147.135 1.00 48.12  ? 203 LEU D O     1 
ATOM   3576 C CB    . LEU B 1 203 ? 131.254 114.267 146.609 1.00 57.49  ? 203 LEU D CB    1 
ATOM   3577 C CG    . LEU B 1 203 ? 130.064 113.429 147.072 1.00 51.95  ? 203 LEU D CG    1 
ATOM   3578 C CD1   . LEU B 1 203 ? 130.273 111.977 146.691 1.00 51.33  ? 203 LEU D CD1   1 
ATOM   3579 C CD2   . LEU B 1 203 ? 129.859 113.567 148.569 1.00 50.58  ? 203 LEU D CD2   1 
ATOM   3580 N N     . VAL B 1 204 ? 132.542 116.993 145.123 1.00 62.61  ? 204 VAL D N     1 
ATOM   3581 C CA    . VAL B 1 204 ? 133.810 117.475 144.591 1.00 65.45  ? 204 VAL D CA    1 
ATOM   3582 C C     . VAL B 1 204 ? 133.814 118.995 144.628 1.00 68.16  ? 204 VAL D C     1 
ATOM   3583 O O     . VAL B 1 204 ? 132.895 119.639 144.108 1.00 63.88  ? 204 VAL D O     1 
ATOM   3584 C CB    . VAL B 1 204 ? 134.045 116.972 143.157 1.00 64.35  ? 204 VAL D CB    1 
ATOM   3585 C CG1   . VAL B 1 204 ? 135.281 117.625 142.572 1.00 61.75  ? 204 VAL D CG1   1 
ATOM   3586 C CG2   . VAL B 1 204 ? 134.169 115.460 143.138 1.00 61.33  ? 204 VAL D CG2   1 
ATOM   3587 N N     . GLY B 1 205 ? 134.848 119.561 145.230 1.00 71.36  ? 205 GLY D N     1 
ATOM   3588 C CA    . GLY B 1 205 ? 135.070 120.991 145.229 1.00 69.27  ? 205 GLY D CA    1 
ATOM   3589 C C     . GLY B 1 205 ? 135.958 121.415 144.082 1.00 66.75  ? 205 GLY D C     1 
ATOM   3590 O O     . GLY B 1 205 ? 135.948 120.816 143.002 1.00 68.05  ? 205 GLY D O     1 
ATOM   3591 N N     . GLY B 1 206 ? 136.742 122.456 144.318 1.00 66.02  ? 206 GLY D N     1 
ATOM   3592 C CA    . GLY B 1 206 ? 137.677 122.947 143.326 1.00 71.26  ? 206 GLY D CA    1 
ATOM   3593 C C     . GLY B 1 206 ? 137.175 124.188 142.615 1.00 80.62  ? 206 GLY D C     1 
ATOM   3594 O O     . GLY B 1 206 ? 136.166 124.801 142.976 1.00 82.06  ? 206 GLY D O     1 
ATOM   3595 N N     . TYR B 1 207 ? 137.912 124.553 141.564 1.00 84.88  ? 207 TYR D N     1 
ATOM   3596 C CA    . TYR B 1 207 ? 137.610 125.787 140.848 1.00 86.00  ? 207 TYR D CA    1 
ATOM   3597 C C     . TYR B 1 207 ? 136.205 125.760 140.263 1.00 86.82  ? 207 TYR D C     1 
ATOM   3598 O O     . TYR B 1 207 ? 135.477 126.756 140.334 1.00 91.66  ? 207 TYR D O     1 
ATOM   3599 C CB    . TYR B 1 207 ? 138.637 126.022 139.742 1.00 88.96  ? 207 TYR D CB    1 
ATOM   3600 C CG    . TYR B 1 207 ? 138.205 127.071 138.744 1.00 96.05  ? 207 TYR D CG    1 
ATOM   3601 C CD1   . TYR B 1 207 ? 138.212 128.419 139.079 1.00 97.62  ? 207 TYR D CD1   1 
ATOM   3602 C CD2   . TYR B 1 207 ? 137.783 126.716 137.471 1.00 100.82 ? 207 TYR D CD2   1 
ATOM   3603 C CE1   . TYR B 1 207 ? 137.814 129.382 138.174 1.00 96.40  ? 207 TYR D CE1   1 
ATOM   3604 C CE2   . TYR B 1 207 ? 137.383 127.673 136.558 1.00 105.27 ? 207 TYR D CE2   1 
ATOM   3605 C CZ    . TYR B 1 207 ? 137.400 129.004 136.916 1.00 101.17 ? 207 TYR D CZ    1 
ATOM   3606 O OH    . TYR B 1 207 ? 137.004 129.960 136.011 1.00 94.57  ? 207 TYR D OH    1 
ATOM   3607 N N     . PHE B 1 208 ? 135.809 124.633 139.670 1.00 83.64  ? 208 PHE D N     1 
ATOM   3608 C CA    . PHE B 1 208 ? 134.478 124.555 139.079 1.00 84.53  ? 208 PHE D CA    1 
ATOM   3609 C C     . PHE B 1 208 ? 133.392 124.634 140.142 1.00 82.35  ? 208 PHE D C     1 
ATOM   3610 O O     . PHE B 1 208 ? 132.318 125.191 139.888 1.00 83.42  ? 208 PHE D O     1 
ATOM   3611 C CB    . PHE B 1 208 ? 134.348 123.274 138.262 1.00 85.05  ? 208 PHE D CB    1 
ATOM   3612 C CG    . PHE B 1 208 ? 135.219 123.253 137.041 1.00 92.10  ? 208 PHE D CG    1 
ATOM   3613 C CD1   . PHE B 1 208 ? 134.758 123.752 135.836 1.00 97.56  ? 208 PHE D CD1   1 
ATOM   3614 C CD2   . PHE B 1 208 ? 136.508 122.753 137.103 1.00 94.86  ? 208 PHE D CD2   1 
ATOM   3615 C CE1   . PHE B 1 208 ? 135.562 123.739 134.712 1.00 103.82 ? 208 PHE D CE1   1 
ATOM   3616 C CE2   . PHE B 1 208 ? 137.316 122.738 135.983 1.00 100.31 ? 208 PHE D CE2   1 
ATOM   3617 C CZ    . PHE B 1 208 ? 136.842 123.232 134.786 1.00 104.64 ? 208 PHE D CZ    1 
ATOM   3618 N N     . ALA B 1 209 ? 133.648 124.094 141.335 1.00 78.06  ? 209 ALA D N     1 
ATOM   3619 C CA    . ALA B 1 209 ? 132.702 124.267 142.431 1.00 77.73  ? 209 ALA D CA    1 
ATOM   3620 C C     . ALA B 1 209 ? 132.555 125.738 142.793 1.00 84.34  ? 209 ALA D C     1 
ATOM   3621 O O     . ALA B 1 209 ? 131.441 126.221 143.026 1.00 87.25  ? 209 ALA D O     1 
ATOM   3622 C CB    . ALA B 1 209 ? 133.152 123.457 143.644 1.00 74.16  ? 209 ALA D CB    1 
ATOM   3623 N N     . LYS B 1 210 ? 133.672 126.468 142.842 1.00 85.54  ? 210 LYS D N     1 
ATOM   3624 C CA    . LYS B 1 210 ? 133.612 127.904 143.094 1.00 83.89  ? 210 LYS D CA    1 
ATOM   3625 C C     . LYS B 1 210 ? 132.794 128.607 142.020 1.00 86.42  ? 210 LYS D C     1 
ATOM   3626 O O     . LYS B 1 210 ? 131.952 129.461 142.319 1.00 84.79  ? 210 LYS D O     1 
ATOM   3627 C CB    . LYS B 1 210 ? 135.025 128.484 143.150 1.00 82.41  ? 210 LYS D CB    1 
ATOM   3628 C CG    . LYS B 1 210 ? 135.762 128.194 144.441 1.00 81.06  ? 210 LYS D CG    1 
ATOM   3629 C CD    . LYS B 1 210 ? 137.265 128.084 144.237 1.00 82.49  ? 210 LYS D CD    1 
ATOM   3630 C CE    . LYS B 1 210 ? 137.886 129.415 143.848 1.00 85.32  ? 210 LYS D CE    1 
ATOM   3631 N NZ    . LYS B 1 210 ? 139.307 129.261 143.431 1.00 86.86  ? 210 LYS D NZ    1 
ATOM   3632 N N     . LYS B 1 211 ? 133.031 128.255 140.757 1.00 86.49  ? 211 LYS D N     1 
ATOM   3633 C CA    . LYS B 1 211 ? 132.311 128.894 139.663 1.00 81.24  ? 211 LYS D CA    1 
ATOM   3634 C C     . LYS B 1 211 ? 130.816 128.630 139.762 1.00 81.30  ? 211 LYS D C     1 
ATOM   3635 O O     . LYS B 1 211 ? 130.002 129.541 139.569 1.00 86.77  ? 211 LYS D O     1 
ATOM   3636 C CB    . LYS B 1 211 ? 132.858 128.398 138.326 1.00 84.55  ? 211 LYS D CB    1 
ATOM   3637 C CG    . LYS B 1 211 ? 132.267 129.092 137.114 1.00 90.85  ? 211 LYS D CG    1 
ATOM   3638 C CD    . LYS B 1 211 ? 132.934 128.618 135.834 1.00 92.84  ? 211 LYS D CD    1 
ATOM   3639 C CE    . LYS B 1 211 ? 132.260 129.203 134.608 1.00 95.19  ? 211 LYS D CE    1 
ATOM   3640 N NZ    . LYS B 1 211 ? 132.883 128.718 133.348 1.00 100.22 ? 211 LYS D NZ    1 
ATOM   3641 N N     . ALA B 1 212 ? 130.433 127.390 140.065 1.00 79.45  ? 212 ALA D N     1 
ATOM   3642 C CA    . ALA B 1 212 ? 129.016 127.060 140.170 1.00 84.05  ? 212 ALA D CA    1 
ATOM   3643 C C     . ALA B 1 212 ? 128.369 127.777 141.350 1.00 88.74  ? 212 ALA D C     1 
ATOM   3644 O O     . ALA B 1 212 ? 127.266 128.320 141.228 1.00 88.78  ? 212 ALA D O     1 
ATOM   3645 C CB    . ALA B 1 212 ? 128.839 125.548 140.296 1.00 86.74  ? 212 ALA D CB    1 
ATOM   3646 N N     . ALA B 1 213 ? 129.038 127.784 142.505 1.00 90.26  ? 213 ALA D N     1 
ATOM   3647 C CA    . ALA B 1 213 ? 128.460 128.418 143.685 1.00 89.84  ? 213 ALA D CA    1 
ATOM   3648 C C     . ALA B 1 213 ? 128.321 129.923 143.497 1.00 94.67  ? 213 ALA D C     1 
ATOM   3649 O O     . ALA B 1 213 ? 127.292 130.507 143.856 1.00 90.43  ? 213 ALA D O     1 
ATOM   3650 C CB    . ALA B 1 213 ? 129.313 128.113 144.914 1.00 86.68  ? 213 ALA D CB    1 
ATOM   3651 N N     . ALA B 1 214 ? 129.348 130.570 142.938 1.00 100.31 ? 214 ALA D N     1 
ATOM   3652 C CA    . ALA B 1 214 ? 129.316 132.021 142.792 1.00 98.16  ? 214 ALA D CA    1 
ATOM   3653 C C     . ALA B 1 214 ? 128.189 132.460 141.867 1.00 97.13  ? 214 ALA D C     1 
ATOM   3654 O O     . ALA B 1 214 ? 127.502 133.452 142.139 1.00 98.25  ? 214 ALA D O     1 
ATOM   3655 C CB    . ALA B 1 214 ? 130.663 132.523 142.273 1.00 91.17  ? 214 ALA D CB    1 
ATOM   3656 N N     . GLY B 1 215 ? 127.979 131.735 140.773 1.00 95.03  ? 215 GLY D N     1 
ATOM   3657 C CA    . GLY B 1 215 ? 126.959 132.083 139.812 1.00 96.84  ? 215 GLY D CA    1 
ATOM   3658 C C     . GLY B 1 215 ? 125.566 131.768 140.322 1.00 103.58 ? 215 GLY D C     1 
ATOM   3659 O O     . GLY B 1 215 ? 125.352 131.408 141.480 1.00 97.09  ? 215 GLY D O     1 
ATOM   3660 N N     . GLU B 1 216 ? 124.598 131.918 139.422 1.00 110.09 ? 216 GLU D N     1 
ATOM   3661 C CA    . GLU B 1 216 ? 123.209 131.668 139.776 1.00 107.26 ? 216 GLU D CA    1 
ATOM   3662 C C     . GLU B 1 216 ? 123.024 130.218 140.205 1.00 102.85 ? 216 GLU D C     1 
ATOM   3663 O O     . GLU B 1 216 ? 123.607 129.300 139.622 1.00 103.45 ? 216 GLU D O     1 
ATOM   3664 C CB    . GLU B 1 216 ? 122.299 131.989 138.590 1.00 109.14 ? 216 GLU D CB    1 
ATOM   3665 C CG    . GLU B 1 216 ? 120.817 131.916 138.905 1.00 108.58 ? 216 GLU D CG    1 
ATOM   3666 C CD    . GLU B 1 216 ? 119.955 132.279 137.714 1.00 114.90 ? 216 GLU D CD    1 
ATOM   3667 O OE1   . GLU B 1 216 ? 120.519 132.524 136.626 1.00 120.23 ? 216 GLU D OE1   1 
ATOM   3668 O OE2   . GLU B 1 216 ? 118.717 132.326 137.865 1.00 113.28 ? 216 GLU D OE2   1 
ATOM   3669 N N     . ARG B 1 217 ? 122.203 130.016 141.232 1.00 101.53 ? 217 ARG D N     1 
ATOM   3670 C CA    . ARG B 1 217 ? 121.933 128.694 141.787 1.00 103.98 ? 217 ARG D CA    1 
ATOM   3671 C C     . ARG B 1 217 ? 120.530 128.272 141.368 1.00 105.10 ? 217 ARG D C     1 
ATOM   3672 O O     . ARG B 1 217 ? 119.537 128.785 141.894 1.00 106.06 ? 217 ARG D O     1 
ATOM   3673 C CB    . ARG B 1 217 ? 122.071 128.705 143.307 1.00 101.66 ? 217 ARG D CB    1 
ATOM   3674 C CG    . ARG B 1 217 ? 123.147 129.648 143.823 1.00 98.88  ? 217 ARG D CG    1 
ATOM   3675 C CD    . ARG B 1 217 ? 123.726 129.175 145.145 1.00 93.60  ? 217 ARG D CD    1 
ATOM   3676 N NE    . ARG B 1 217 ? 125.054 129.723 145.384 1.00 93.51  ? 217 ARG D NE    1 
ATOM   3677 C CZ    . ARG B 1 217 ? 125.709 129.625 146.533 1.00 93.80  ? 217 ARG D CZ    1 
ATOM   3678 N NH1   . ARG B 1 217 ? 125.190 128.994 147.574 1.00 90.48  ? 217 ARG D NH1   1 
ATOM   3679 N NH2   . ARG B 1 217 ? 126.917 130.170 146.639 1.00 89.84  ? 217 ARG D NH2   1 
ATOM   3680 N N     . GLY B 1 218 ? 120.452 127.338 140.426 1.00 104.62 ? 218 GLY D N     1 
ATOM   3681 C CA    . GLY B 1 218 ? 119.189 126.828 139.938 1.00 101.66 ? 218 GLY D CA    1 
ATOM   3682 C C     . GLY B 1 218 ? 118.711 125.628 140.727 1.00 102.37 ? 218 GLY D C     1 
ATOM   3683 O O     . GLY B 1 218 ? 119.213 125.318 141.811 1.00 101.98 ? 218 GLY D O     1 
ATOM   3684 N N     . LYS B 1 219 ? 117.715 124.941 140.165 1.00 104.47 ? 219 LYS D N     1 
ATOM   3685 C CA    . LYS B 1 219 ? 117.171 123.758 140.824 1.00 100.66 ? 219 LYS D CA    1 
ATOM   3686 C C     . LYS B 1 219 ? 118.145 122.589 140.768 1.00 102.08 ? 219 LYS D C     1 
ATOM   3687 O O     . LYS B 1 219 ? 118.175 121.766 141.691 1.00 100.73 ? 219 LYS D O     1 
ATOM   3688 C CB    . LYS B 1 219 ? 115.840 123.363 140.184 1.00 101.57 ? 219 LYS D CB    1 
ATOM   3689 C CG    . LYS B 1 219 ? 114.792 124.468 140.181 1.00 100.98 ? 219 LYS D CG    1 
ATOM   3690 C CD    . LYS B 1 219 ? 113.805 124.296 139.037 1.00 97.38  ? 219 LYS D CD    1 
ATOM   3691 C CE    . LYS B 1 219 ? 112.886 125.499 138.909 1.00 99.83  ? 219 LYS D CE    1 
ATOM   3692 N NZ    . LYS B 1 219 ? 111.822 125.283 137.891 1.00 105.33 ? 219 LYS D NZ    1 
ATOM   3693 N N     . ASN B 1 220 ? 118.943 122.495 139.704 1.00 105.36 ? 220 ASN D N     1 
ATOM   3694 C CA    . ASN B 1 220 ? 119.905 121.410 139.561 1.00 107.56 ? 220 ASN D CA    1 
ATOM   3695 C C     . ASN B 1 220 ? 121.180 121.636 140.361 1.00 103.60 ? 220 ASN D C     1 
ATOM   3696 O O     . ASN B 1 220 ? 121.983 120.706 140.491 1.00 95.82  ? 220 ASN D O     1 
ATOM   3697 C CB    . ASN B 1 220 ? 120.263 121.219 138.086 1.00 104.46 ? 220 ASN D CB    1 
ATOM   3698 C CG    . ASN B 1 220 ? 121.477 122.028 137.672 1.00 104.32 ? 220 ASN D CG    1 
ATOM   3699 O OD1   . ASN B 1 220 ? 121.573 123.220 137.963 1.00 101.92 ? 220 ASN D OD1   1 
ATOM   3700 N ND2   . ASN B 1 220 ? 122.413 121.382 136.988 1.00 107.91 ? 220 ASN D ND2   1 
ATOM   3701 N N     . TYR B 1 221 ? 121.386 122.837 140.894 1.00 101.02 ? 221 TYR D N     1 
ATOM   3702 C CA    . TYR B 1 221 ? 122.594 123.123 141.654 1.00 95.55  ? 221 TYR D CA    1 
ATOM   3703 C C     . TYR B 1 221 ? 122.617 122.307 142.941 1.00 99.88  ? 221 TYR D C     1 
ATOM   3704 O O     . TYR B 1 221 ? 121.610 122.216 143.650 1.00 101.19 ? 221 TYR D O     1 
ATOM   3705 C CB    . TYR B 1 221 ? 122.675 124.614 141.974 1.00 92.53  ? 221 TYR D CB    1 
ATOM   3706 C CG    . TYR B 1 221 ? 123.820 124.971 142.887 1.00 94.91  ? 221 TYR D CG    1 
ATOM   3707 C CD1   . TYR B 1 221 ? 125.105 125.137 142.390 1.00 95.55  ? 221 TYR D CD1   1 
ATOM   3708 C CD2   . TYR B 1 221 ? 123.619 125.131 144.250 1.00 95.73  ? 221 TYR D CD2   1 
ATOM   3709 C CE1   . TYR B 1 221 ? 126.157 125.461 143.226 1.00 95.01  ? 221 TYR D CE1   1 
ATOM   3710 C CE2   . TYR B 1 221 ? 124.663 125.452 145.092 1.00 96.78  ? 221 TYR D CE2   1 
ATOM   3711 C CZ    . TYR B 1 221 ? 125.929 125.616 144.576 1.00 98.24  ? 221 TYR D CZ    1 
ATOM   3712 O OH    . TYR B 1 221 ? 126.968 125.936 145.418 1.00 97.00  ? 221 TYR D OH    1 
ATOM   3713 N N     . LYS B 1 222 ? 123.772 121.719 143.244 1.00 100.12 ? 222 LYS D N     1 
ATOM   3714 C CA    . LYS B 1 222 ? 123.983 120.964 144.472 1.00 96.87  ? 222 LYS D CA    1 
ATOM   3715 C C     . LYS B 1 222 ? 125.076 121.638 145.286 1.00 91.44  ? 222 LYS D C     1 
ATOM   3716 O O     . LYS B 1 222 ? 126.169 121.894 144.771 1.00 89.80  ? 222 LYS D O     1 
ATOM   3717 C CB    . LYS B 1 222 ? 124.372 119.514 144.175 1.00 93.02  ? 222 LYS D CB    1 
ATOM   3718 C CG    . LYS B 1 222 ? 123.262 118.679 143.568 1.00 95.63  ? 222 LYS D CG    1 
ATOM   3719 C CD    . LYS B 1 222 ? 123.691 117.230 143.411 1.00 91.64  ? 222 LYS D CD    1 
ATOM   3720 C CE    . LYS B 1 222 ? 122.697 116.440 142.577 1.00 96.01  ? 222 LYS D CE    1 
ATOM   3721 N NZ    . LYS B 1 222 ? 123.210 115.086 142.232 1.00 94.49  ? 222 LYS D NZ    1 
ATOM   3722 N N     . LYS B 1 223 ? 124.781 121.923 146.551 1.00 86.79  ? 223 LYS D N     1 
ATOM   3723 C CA    . LYS B 1 223 ? 125.771 122.541 147.420 1.00 91.59  ? 223 LYS D CA    1 
ATOM   3724 C C     . LYS B 1 223 ? 126.900 121.562 147.717 1.00 89.82  ? 223 LYS D C     1 
ATOM   3725 O O     . LYS B 1 223 ? 126.675 120.361 147.887 1.00 85.94  ? 223 LYS D O     1 
ATOM   3726 C CB    . LYS B 1 223 ? 125.123 123.006 148.723 1.00 96.99  ? 223 LYS D CB    1 
ATOM   3727 C CG    . LYS B 1 223 ? 126.033 123.868 149.586 1.00 98.81  ? 223 LYS D CG    1 
ATOM   3728 C CD    . LYS B 1 223 ? 125.282 124.497 150.748 1.00 98.80  ? 223 LYS D CD    1 
ATOM   3729 C CE    . LYS B 1 223 ? 126.198 125.373 151.588 1.00 100.77 ? 223 LYS D CE    1 
ATOM   3730 N NZ    . LYS B 1 223 ? 125.479 126.032 152.712 1.00 96.82  ? 223 LYS D NZ    1 
ATOM   3731 N N     . LEU B 1 224 ? 128.121 122.085 147.779 1.00 84.22  ? 224 LEU D N     1 
ATOM   3732 C CA    . LEU B 1 224 ? 129.292 121.265 148.067 1.00 74.22  ? 224 LEU D CA    1 
ATOM   3733 C C     . LEU B 1 224 ? 129.210 120.754 149.500 1.00 77.44  ? 224 LEU D C     1 
ATOM   3734 O O     . LEU B 1 224 ? 129.374 121.525 150.451 1.00 78.40  ? 224 LEU D O     1 
ATOM   3735 C CB    . LEU B 1 224 ? 130.565 122.076 147.847 1.00 70.98  ? 224 LEU D CB    1 
ATOM   3736 C CG    . LEU B 1 224 ? 131.879 121.403 148.247 1.00 65.62  ? 224 LEU D CG    1 
ATOM   3737 C CD1   . LEU B 1 224 ? 132.144 120.190 147.378 1.00 67.59  ? 224 LEU D CD1   1 
ATOM   3738 C CD2   . LEU B 1 224 ? 133.029 122.388 148.156 1.00 66.99  ? 224 LEU D CD2   1 
ATOM   3739 N N     . ASN B 1 225 ? 128.954 119.457 149.659 1.00 77.24  ? 225 ASN D N     1 
ATOM   3740 C CA    . ASN B 1 225 ? 128.923 118.825 150.978 1.00 75.68  ? 225 ASN D CA    1 
ATOM   3741 C C     . ASN B 1 225 ? 130.335 118.350 151.289 1.00 68.76  ? 225 ASN D C     1 
ATOM   3742 O O     . ASN B 1 225 ? 130.731 117.235 150.950 1.00 65.38  ? 225 ASN D O     1 
ATOM   3743 C CB    . ASN B 1 225 ? 127.920 117.679 151.007 1.00 74.74  ? 225 ASN D CB    1 
ATOM   3744 C CG    . ASN B 1 225 ? 126.492 118.151 150.829 1.00 81.26  ? 225 ASN D CG    1 
ATOM   3745 O OD1   . ASN B 1 225 ? 125.802 117.740 149.895 1.00 80.76  ? 225 ASN D OD1   1 
ATOM   3746 N ND2   . ASN B 1 225 ? 126.040 119.022 151.724 1.00 82.98  ? 225 ASN D ND2   1 
ATOM   3747 N N     . GLN B 1 226 ? 131.106 119.212 151.950 1.00 61.58  ? 226 GLN D N     1 
ATOM   3748 C CA    . GLN B 1 226 ? 132.512 118.917 152.187 1.00 59.73  ? 226 GLN D CA    1 
ATOM   3749 C C     . GLN B 1 226 ? 132.715 117.689 153.062 1.00 58.50  ? 226 GLN D C     1 
ATOM   3750 O O     . GLN B 1 226 ? 133.757 117.035 152.951 1.00 60.33  ? 226 GLN D O     1 
ATOM   3751 C CB    . GLN B 1 226 ? 133.194 120.125 152.828 1.00 61.55  ? 226 GLN D CB    1 
ATOM   3752 C CG    . GLN B 1 226 ? 134.693 120.158 152.625 1.00 62.31  ? 226 GLN D CG    1 
ATOM   3753 C CD    . GLN B 1 226 ? 135.314 121.451 153.103 1.00 61.31  ? 226 GLN D CD    1 
ATOM   3754 O OE1   . GLN B 1 226 ? 135.325 121.744 154.297 1.00 57.58  ? 226 GLN D OE1   1 
ATOM   3755 N NE2   . GLN B 1 226 ? 135.831 122.237 152.169 1.00 63.05  ? 226 GLN D NE2   1 
ATOM   3756 N N     . THR B 1 227 ? 131.750 117.354 153.921 1.00 59.53  ? 227 THR D N     1 
ATOM   3757 C CA    . THR B 1 227 ? 131.904 116.246 154.858 1.00 58.53  ? 227 THR D CA    1 
ATOM   3758 C C     . THR B 1 227 ? 130.806 115.201 154.698 1.00 60.98  ? 227 THR D C     1 
ATOM   3759 O O     . THR B 1 227 ? 130.503 114.483 155.656 1.00 57.78  ? 227 THR D O     1 
ATOM   3760 C CB    . THR B 1 227 ? 131.923 116.756 156.300 1.00 60.55  ? 227 THR D CB    1 
ATOM   3761 O OG1   . THR B 1 227 ? 130.693 117.434 156.585 1.00 69.06  ? 227 THR D OG1   1 
ATOM   3762 C CG2   . THR B 1 227 ? 133.088 117.709 156.515 1.00 58.46  ? 227 THR D CG2   1 
ATOM   3763 N N     . ALA B 1 228 ? 130.202 115.098 153.517 1.00 64.74  ? 228 ALA D N     1 
ATOM   3764 C CA    . ALA B 1 228 ? 129.219 114.050 153.284 1.00 63.14  ? 228 ALA D CA    1 
ATOM   3765 C C     . ALA B 1 228 ? 129.868 112.683 153.452 1.00 58.86  ? 228 ALA D C     1 
ATOM   3766 O O     . ALA B 1 228 ? 131.035 112.478 153.110 1.00 59.58  ? 228 ALA D O     1 
ATOM   3767 C CB    . ALA B 1 228 ? 128.618 114.179 151.886 1.00 64.06  ? 228 ALA D CB    1 
ATOM   3768 N N     . ILE B 1 229 ? 129.103 111.743 153.989 1.00 55.89  ? 229 ILE D N     1 
ATOM   3769 C CA    . ILE B 1 229 ? 129.640 110.430 154.320 1.00 55.77  ? 229 ILE D CA    1 
ATOM   3770 C C     . ILE B 1 229 ? 129.908 109.663 153.033 1.00 54.22  ? 229 ILE D C     1 
ATOM   3771 O O     . ILE B 1 229 ? 129.024 109.526 152.180 1.00 57.29  ? 229 ILE D O     1 
ATOM   3772 C CB    . ILE B 1 229 ? 128.676 109.662 155.239 1.00 59.45  ? 229 ILE D CB    1 
ATOM   3773 C CG1   . ILE B 1 229 ? 128.393 110.469 156.511 1.00 59.77  ? 229 ILE D CG1   1 
ATOM   3774 C CG2   . ILE B 1 229 ? 129.257 108.303 155.605 1.00 58.49  ? 229 ILE D CG2   1 
ATOM   3775 C CD1   . ILE B 1 229 ? 127.133 111.311 156.447 1.00 61.96  ? 229 ILE D CD1   1 
ATOM   3776 N N     . ILE B 1 230 ? 131.135 109.177 152.886 1.00 53.42  ? 230 ILE D N     1 
ATOM   3777 C CA    . ILE B 1 230 ? 131.543 108.333 151.771 1.00 50.97  ? 230 ILE D CA    1 
ATOM   3778 C C     . ILE B 1 230 ? 132.133 107.058 152.360 1.00 53.47  ? 230 ILE D C     1 
ATOM   3779 O O     . ILE B 1 230 ? 133.144 107.117 153.064 1.00 57.58  ? 230 ILE D O     1 
ATOM   3780 C CB    . ILE B 1 230 ? 132.565 109.028 150.855 1.00 43.07  ? 230 ILE D CB    1 
ATOM   3781 C CG1   . ILE B 1 230 ? 131.877 110.085 149.993 1.00 45.83  ? 230 ILE D CG1   1 
ATOM   3782 C CG2   . ILE B 1 230 ? 133.277 108.008 149.976 1.00 37.84  ? 230 ILE D CG2   1 
ATOM   3783 C CD1   . ILE B 1 230 ? 132.836 111.042 149.331 1.00 44.87  ? 230 ILE D CD1   1 
ATOM   3784 N N     . PRO B 1 231 ? 131.550 105.887 152.119 1.00 57.73  ? 231 PRO D N     1 
ATOM   3785 C CA    . PRO B 1 231 ? 132.163 104.663 152.619 1.00 60.48  ? 231 PRO D CA    1 
ATOM   3786 C C     . PRO B 1 231 ? 133.561 104.502 152.060 1.00 57.84  ? 231 PRO D C     1 
ATOM   3787 O O     . PRO B 1 231 ? 133.845 104.925 150.924 1.00 53.38  ? 231 PRO D O     1 
ATOM   3788 C CB    . PRO B 1 231 ? 131.220 103.564 152.112 1.00 58.97  ? 231 PRO D CB    1 
ATOM   3789 C CG    . PRO B 1 231 ? 129.914 104.235 151.933 1.00 60.10  ? 231 PRO D CG    1 
ATOM   3790 C CD    . PRO B 1 231 ? 130.219 105.644 151.537 1.00 58.94  ? 231 PRO D CD    1 
ATOM   3791 N N     . PRO B 1 232 ? 134.476 103.909 152.825 1.00 54.84  ? 232 PRO D N     1 
ATOM   3792 C CA    . PRO B 1 232 ? 135.814 103.677 152.299 1.00 52.53  ? 232 PRO D CA    1 
ATOM   3793 C C     . PRO B 1 232 ? 135.749 102.873 151.017 1.00 55.38  ? 232 PRO D C     1 
ATOM   3794 O O     . PRO B 1 232 ? 134.773 102.138 150.775 1.00 60.13  ? 232 PRO D O     1 
ATOM   3795 C CB    . PRO B 1 232 ? 136.507 102.893 153.422 1.00 52.13  ? 232 PRO D CB    1 
ATOM   3796 C CG    . PRO B 1 232 ? 135.768 103.232 154.643 1.00 52.72  ? 232 PRO D CG    1 
ATOM   3797 C CD    . PRO B 1 232 ? 134.361 103.510 154.238 1.00 55.52  ? 232 PRO D CD    1 
ATOM   3798 N N     . PRO B 1 233 ? 136.762 102.988 150.155 1.00 49.04  ? 233 PRO D N     1 
ATOM   3799 C CA    . PRO B 1 233 ? 136.709 102.246 148.886 1.00 50.29  ? 233 PRO D CA    1 
ATOM   3800 C C     . PRO B 1 233 ? 136.505 100.754 149.067 1.00 59.40  ? 233 PRO D C     1 
ATOM   3801 O O     . PRO B 1 233 ? 135.787 100.136 148.272 1.00 64.66  ? 233 PRO D O     1 
ATOM   3802 C CB    . PRO B 1 233 ? 138.064 102.563 148.245 1.00 50.79  ? 233 PRO D CB    1 
ATOM   3803 C CG    . PRO B 1 233 ? 138.460 103.863 148.821 1.00 46.73  ? 233 PRO D CG    1 
ATOM   3804 C CD    . PRO B 1 233 ? 137.912 103.902 150.210 1.00 49.19  ? 233 PRO D CD    1 
ATOM   3805 N N     . ARG B 1 234 ? 137.109 100.150 150.090 1.00 62.31  ? 234 ARG D N     1 
ATOM   3806 C CA    . ARG B 1 234 ? 136.907 98.726  150.321 1.00 63.09  ? 234 ARG D CA    1 
ATOM   3807 C C     . ARG B 1 234 ? 135.482 98.401  150.745 1.00 62.81  ? 234 ARG D C     1 
ATOM   3808 O O     . ARG B 1 234 ? 135.102 97.226  150.725 1.00 64.10  ? 234 ARG D O     1 
ATOM   3809 C CB    . ARG B 1 234 ? 137.900 98.219  151.367 1.00 65.06  ? 234 ARG D CB    1 
ATOM   3810 C CG    . ARG B 1 234 ? 137.700 98.783  152.757 1.00 69.28  ? 234 ARG D CG    1 
ATOM   3811 C CD    . ARG B 1 234 ? 138.898 98.471  153.640 1.00 72.54  ? 234 ARG D CD    1 
ATOM   3812 N NE    . ARG B 1 234 ? 138.618 98.676  155.057 1.00 68.98  ? 234 ARG D NE    1 
ATOM   3813 C CZ    . ARG B 1 234 ? 138.136 97.745  155.869 1.00 67.38  ? 234 ARG D CZ    1 
ATOM   3814 N NH1   . ARG B 1 234 ? 137.843 96.531  155.435 1.00 64.97  ? 234 ARG D NH1   1 
ATOM   3815 N NH2   . ARG B 1 234 ? 137.939 98.042  157.150 1.00 70.84  ? 234 ARG D NH2   1 
ATOM   3816 N N     . PHE B 1 235 ? 134.693 99.402  151.130 1.00 63.30  ? 235 PHE D N     1 
ATOM   3817 C CA    . PHE B 1 235 ? 133.265 99.237  151.369 1.00 63.84  ? 235 PHE D CA    1 
ATOM   3818 C C     . PHE B 1 235 ? 132.421 99.700  150.191 1.00 65.12  ? 235 PHE D C     1 
ATOM   3819 O O     . PHE B 1 235 ? 131.403 99.076  149.882 1.00 72.10  ? 235 PHE D O     1 
ATOM   3820 C CB    . PHE B 1 235 ? 132.836 100.017 152.618 1.00 66.25  ? 235 PHE D CB    1 
ATOM   3821 C CG    . PHE B 1 235 ? 133.405 99.482  153.901 1.00 71.24  ? 235 PHE D CG    1 
ATOM   3822 C CD1   . PHE B 1 235 ? 132.793 98.433  154.562 1.00 74.45  ? 235 PHE D CD1   1 
ATOM   3823 C CD2   . PHE B 1 235 ? 134.546 100.037 154.453 1.00 69.33  ? 235 PHE D CD2   1 
ATOM   3824 C CE1   . PHE B 1 235 ? 133.313 97.944  155.743 1.00 74.50  ? 235 PHE D CE1   1 
ATOM   3825 C CE2   . PHE B 1 235 ? 135.069 99.551  155.633 1.00 67.46  ? 235 PHE D CE2   1 
ATOM   3826 C CZ    . PHE B 1 235 ? 134.453 98.504  156.278 1.00 69.28  ? 235 PHE D CZ    1 
ATOM   3827 N N     . LEU B 1 236 ? 132.829 100.780 149.523 1.00 60.27  ? 236 LEU D N     1 
ATOM   3828 C CA    . LEU B 1 236 ? 132.005 101.363 148.469 1.00 61.25  ? 236 LEU D CA    1 
ATOM   3829 C C     . LEU B 1 236 ? 131.813 100.390 147.313 1.00 64.24  ? 236 LEU D C     1 
ATOM   3830 O O     . LEU B 1 236 ? 130.698 100.224 146.807 1.00 65.29  ? 236 LEU D O     1 
ATOM   3831 C CB    . LEU B 1 236 ? 132.640 102.665 147.983 1.00 57.95  ? 236 LEU D CB    1 
ATOM   3832 C CG    . LEU B 1 236 ? 131.931 103.404 146.851 1.00 50.08  ? 236 LEU D CG    1 
ATOM   3833 C CD1   . LEU B 1 236 ? 130.470 103.621 147.181 1.00 50.75  ? 236 LEU D CD1   1 
ATOM   3834 C CD2   . LEU B 1 236 ? 132.617 104.728 146.599 1.00 46.53  ? 236 LEU D CD2   1 
ATOM   3835 N N     . ILE B 1 237 ? 132.890 99.731  146.881 1.00 64.35  ? 237 ILE D N     1 
ATOM   3836 C CA    . ILE B 1 237 ? 132.782 98.807  145.757 1.00 64.91  ? 237 ILE D CA    1 
ATOM   3837 C C     . ILE B 1 237 ? 131.927 97.604  146.135 1.00 70.10  ? 237 ILE D C     1 
ATOM   3838 O O     . ILE B 1 237 ? 131.194 97.060  145.302 1.00 69.48  ? 237 ILE D O     1 
ATOM   3839 C CB    . ILE B 1 237 ? 134.181 98.385  145.271 1.00 66.07  ? 237 ILE D CB    1 
ATOM   3840 C CG1   . ILE B 1 237 ? 134.926 97.601  146.353 1.00 68.26  ? 237 ILE D CG1   1 
ATOM   3841 C CG2   . ILE B 1 237 ? 134.978 99.608  144.858 1.00 62.16  ? 237 ILE D CG2   1 
ATOM   3842 C CD1   . ILE B 1 237 ? 136.295 97.117  145.922 1.00 64.35  ? 237 ILE D CD1   1 
ATOM   3843 N N     . ILE B 1 238 ? 132.014 97.160  147.391 1.00 74.54  ? 238 ILE D N     1 
ATOM   3844 C CA    . ILE B 1 238 ? 131.166 96.068  147.851 1.00 78.29  ? 238 ILE D CA    1 
ATOM   3845 C C     . ILE B 1 238 ? 129.740 96.542  148.101 1.00 77.61  ? 238 ILE D C     1 
ATOM   3846 O O     . ILE B 1 238 ? 128.811 95.727  148.103 1.00 77.97  ? 238 ILE D O     1 
ATOM   3847 C CB    . ILE B 1 238 ? 131.774 95.431  149.116 1.00 76.62  ? 238 ILE D CB    1 
ATOM   3848 C CG1   . ILE B 1 238 ? 132.862 94.429  148.721 1.00 75.75  ? 238 ILE D CG1   1 
ATOM   3849 C CG2   . ILE B 1 238 ? 130.693 94.752  149.960 1.00 77.46  ? 238 ILE D CG2   1 
ATOM   3850 C CD1   . ILE B 1 238 ? 133.505 93.713  149.891 1.00 73.01  ? 238 ILE D CD1   1 
ATOM   3851 N N     . GLY B 1 239 ? 129.537 97.841  148.305 1.00 70.59  ? 239 GLY D N     1 
ATOM   3852 C CA    . GLY B 1 239 ? 128.228 98.371  148.615 1.00 66.16  ? 239 GLY D CA    1 
ATOM   3853 C C     . GLY B 1 239 ? 127.840 98.293  150.072 1.00 73.45  ? 239 GLY D C     1 
ATOM   3854 O O     . GLY B 1 239 ? 126.733 98.720  150.423 1.00 82.57  ? 239 GLY D O     1 
ATOM   3855 N N     . HIS B 1 240 ? 128.709 97.767  150.932 1.00 73.68  ? 240 HIS D N     1 
ATOM   3856 C CA    . HIS B 1 240 ? 128.425 97.676  152.359 1.00 78.74  ? 240 HIS D CA    1 
ATOM   3857 C C     . HIS B 1 240 ? 128.440 99.075  152.965 1.00 80.53  ? 240 HIS D C     1 
ATOM   3858 O O     . HIS B 1 240 ? 129.507 99.660  153.166 1.00 83.48  ? 240 HIS D O     1 
ATOM   3859 C CB    . HIS B 1 240 ? 129.452 96.774  153.035 1.00 76.34  ? 240 HIS D CB    1 
ATOM   3860 C CG    . HIS B 1 240 ? 129.261 96.636  154.513 1.00 80.29  ? 240 HIS D CG    1 
ATOM   3861 N ND1   . HIS B 1 240 ? 128.106 97.029  155.154 1.00 88.21  ? 240 HIS D ND1   1 
ATOM   3862 C CD2   . HIS B 1 240 ? 130.080 96.153  155.476 1.00 83.56  ? 240 HIS D CD2   1 
ATOM   3863 C CE1   . HIS B 1 240 ? 128.221 96.790  156.449 1.00 93.05  ? 240 HIS D CE1   1 
ATOM   3864 N NE2   . HIS B 1 240 ? 129.410 96.259  156.670 1.00 91.21  ? 240 HIS D NE2   1 
ATOM   3865 N N     . ARG B 1 241 ? 127.258 99.612  153.257 1.00 78.18  ? 241 ARG D N     1 
ATOM   3866 C CA    . ARG B 1 241 ? 127.166 100.960 153.801 1.00 76.77  ? 241 ARG D CA    1 
ATOM   3867 C C     . ARG B 1 241 ? 127.898 101.047 155.133 1.00 80.08  ? 241 ARG D C     1 
ATOM   3868 O O     . ARG B 1 241 ? 127.740 100.184 156.001 1.00 81.04  ? 241 ARG D O     1 
ATOM   3869 C CB    . ARG B 1 241 ? 125.698 101.355 153.973 1.00 79.39  ? 241 ARG D CB    1 
ATOM   3870 C CG    . ARG B 1 241 ? 125.460 102.597 154.831 1.00 81.01  ? 241 ARG D CG    1 
ATOM   3871 C CD    . ARG B 1 241 ? 126.126 103.837 154.250 1.00 79.56  ? 241 ARG D CD    1 
ATOM   3872 N NE    . ARG B 1 241 ? 126.071 104.965 155.172 1.00 78.64  ? 241 ARG D NE    1 
ATOM   3873 C CZ    . ARG B 1 241 ? 126.170 106.238 154.813 1.00 73.49  ? 241 ARG D CZ    1 
ATOM   3874 N NH1   . ARG B 1 241 ? 126.329 106.591 153.548 1.00 68.43  ? 241 ARG D NH1   1 
ATOM   3875 N NH2   . ARG B 1 241 ? 126.107 107.182 155.747 1.00 68.87  ? 241 ARG D NH2   1 
ATOM   3876 N N     . LEU B 1 242 ? 128.705 102.094 155.289 1.00 76.28  ? 242 LEU D N     1 
ATOM   3877 C CA    . LEU B 1 242 ? 129.397 102.328 156.549 1.00 73.70  ? 242 LEU D CA    1 
ATOM   3878 C C     . LEU B 1 242 ? 128.386 102.478 157.678 1.00 79.19  ? 242 LEU D C     1 
ATOM   3879 O O     . LEU B 1 242 ? 127.426 103.245 157.568 1.00 80.47  ? 242 LEU D O     1 
ATOM   3880 C CB    . LEU B 1 242 ? 130.262 103.584 156.440 1.00 68.85  ? 242 LEU D CB    1 
ATOM   3881 C CG    . LEU B 1 242 ? 131.118 103.957 157.650 1.00 69.57  ? 242 LEU D CG    1 
ATOM   3882 C CD1   . LEU B 1 242 ? 132.312 103.027 157.781 1.00 70.30  ? 242 LEU D CD1   1 
ATOM   3883 C CD2   . LEU B 1 242 ? 131.568 105.402 157.547 1.00 66.14  ? 242 LEU D CD2   1 
ATOM   3884 N N     . GLN B 1 243 ? 128.606 101.750 158.769 1.00 85.70  ? 243 GLN D N     1 
ATOM   3885 C CA    . GLN B 1 243 ? 127.693 101.779 159.902 1.00 87.80  ? 243 GLN D CA    1 
ATOM   3886 C C     . GLN B 1 243 ? 128.458 101.407 161.165 1.00 87.25  ? 243 GLN D C     1 
ATOM   3887 O O     . GLN B 1 243 ? 129.661 101.134 161.133 1.00 85.70  ? 243 GLN D O     1 
ATOM   3888 C CB    . GLN B 1 243 ? 126.491 100.853 159.665 1.00 91.04  ? 243 GLN D CB    1 
ATOM   3889 C CG    . GLN B 1 243 ? 126.708 99.381  160.021 1.00 92.95  ? 243 GLN D CG    1 
ATOM   3890 C CD    . GLN B 1 243 ? 125.404 98.626  160.168 1.00 95.76  ? 243 GLN D CD    1 
ATOM   3891 O OE1   . GLN B 1 243 ? 125.103 98.086  161.232 1.00 92.78  ? 243 GLN D OE1   1 
ATOM   3892 N NE2   . GLN B 1 243 ? 124.620 98.587  159.098 1.00 95.39  ? 243 GLN D NE2   1 
ATOM   3893 N N     . ILE B 1 244 ? 127.737 101.396 162.287 1.00 86.40  ? 244 ILE D N     1 
ATOM   3894 C CA    . ILE B 1 244 ? 128.342 101.093 163.576 1.00 90.29  ? 244 ILE D CA    1 
ATOM   3895 C C     . ILE B 1 244 ? 128.775 99.634  163.614 1.00 89.18  ? 244 ILE D C     1 
ATOM   3896 O O     . ILE B 1 244 ? 128.058 98.739  163.148 1.00 93.12  ? 244 ILE D O     1 
ATOM   3897 C CB    . ILE B 1 244 ? 127.353 101.406 164.711 1.00 90.95  ? 244 ILE D CB    1 
ATOM   3898 C CG1   . ILE B 1 244 ? 126.930 102.877 164.665 1.00 89.87  ? 244 ILE D CG1   1 
ATOM   3899 C CG2   . ILE B 1 244 ? 127.972 101.076 166.060 1.00 87.42  ? 244 ILE D CG2   1 
ATOM   3900 C CD1   . ILE B 1 244 ? 125.542 103.129 165.206 1.00 90.77  ? 244 ILE D CD1   1 
ATOM   3901 N N     . GLY B 1 245 ? 129.959 99.387  164.172 1.00 83.08  ? 245 GLY D N     1 
ATOM   3902 C CA    . GLY B 1 245 ? 130.467 98.050  164.373 1.00 81.41  ? 245 GLY D CA    1 
ATOM   3903 C C     . GLY B 1 245 ? 131.493 97.597  163.355 1.00 85.12  ? 245 GLY D C     1 
ATOM   3904 O O     . GLY B 1 245 ? 132.213 96.627  163.616 1.00 89.24  ? 245 GLY D O     1 
ATOM   3905 N N     . ASP B 1 246 ? 131.583 98.266  162.209 1.00 86.23  ? 246 ASP D N     1 
ATOM   3906 C CA    . ASP B 1 246 ? 132.552 97.874  161.195 1.00 86.66  ? 246 ASP D CA    1 
ATOM   3907 C C     . ASP B 1 246 ? 133.970 98.128  161.691 1.00 81.92  ? 246 ASP D C     1 
ATOM   3908 O O     . ASP B 1 246 ? 134.254 99.158  162.306 1.00 82.21  ? 246 ASP D O     1 
ATOM   3909 C CB    . ASP B 1 246 ? 132.301 98.642  159.899 1.00 85.36  ? 246 ASP D CB    1 
ATOM   3910 C CG    . ASP B 1 246 ? 130.936 98.349  159.302 1.00 91.88  ? 246 ASP D CG    1 
ATOM   3911 O OD1   . ASP B 1 246 ? 129.930 98.874  159.825 1.00 89.85  ? 246 ASP D OD1   1 
ATOM   3912 O OD2   . ASP B 1 246 ? 130.867 97.591  158.312 1.00 92.46  ? 246 ASP D OD2   1 
ATOM   3913 N N     . GLN B 1 247 ? 134.864 97.180  161.419 1.00 80.50  ? 247 GLN D N     1 
ATOM   3914 C CA    . GLN B 1 247 ? 136.257 97.282  161.851 1.00 80.66  ? 247 GLN D CA    1 
ATOM   3915 C C     . GLN B 1 247 ? 137.013 98.144  160.850 1.00 75.53  ? 247 GLN D C     1 
ATOM   3916 O O     . GLN B 1 247 ? 137.255 97.733  159.714 1.00 82.06  ? 247 GLN D O     1 
ATOM   3917 C CB    . GLN B 1 247 ? 136.886 95.899  161.970 1.00 85.11  ? 247 GLN D CB    1 
ATOM   3918 C CG    . GLN B 1 247 ? 136.511 95.154  163.237 1.00 89.83  ? 247 GLN D CG    1 
ATOM   3919 C CD    . GLN B 1 247 ? 137.519 94.080  163.599 1.00 96.05  ? 247 GLN D CD    1 
ATOM   3920 O OE1   . GLN B 1 247 ? 138.314 93.652  162.763 1.00 93.96  ? 247 GLN D OE1   1 
ATOM   3921 N NE2   . GLN B 1 247 ? 137.484 93.632  164.848 1.00 101.48 ? 247 GLN D NE2   1 
ATOM   3922 N N     . VAL B 1 248 ? 137.396 99.349  161.273 1.00 69.69  ? 248 VAL D N     1 
ATOM   3923 C CA    . VAL B 1 248 ? 138.088 100.297 160.415 1.00 68.04  ? 248 VAL D CA    1 
ATOM   3924 C C     . VAL B 1 248 ? 139.257 100.904 161.176 1.00 71.50  ? 248 VAL D C     1 
ATOM   3925 O O     . VAL B 1 248 ? 139.264 100.970 162.407 1.00 76.74  ? 248 VAL D O     1 
ATOM   3926 C CB    . VAL B 1 248 ? 137.147 101.410 159.916 1.00 66.03  ? 248 VAL D CB    1 
ATOM   3927 C CG1   . VAL B 1 248 ? 136.089 100.831 159.002 1.00 74.93  ? 248 VAL D CG1   1 
ATOM   3928 C CG2   . VAL B 1 248 ? 136.503 102.122 161.089 1.00 65.97  ? 248 VAL D CG2   1 
ATOM   3929 N N     . THR B 1 249 ? 140.257 101.347 160.421 1.00 73.53  ? 249 THR D N     1 
ATOM   3930 C CA    . THR B 1 249 ? 141.359 102.104 160.991 1.00 72.69  ? 249 THR D CA    1 
ATOM   3931 C C     . THR B 1 249 ? 140.909 103.532 161.274 1.00 69.45  ? 249 THR D C     1 
ATOM   3932 O O     . THR B 1 249 ? 139.985 104.050 160.643 1.00 69.38  ? 249 THR D O     1 
ATOM   3933 C CB    . THR B 1 249 ? 142.556 102.111 160.040 1.00 75.16  ? 249 THR D CB    1 
ATOM   3934 O OG1   . THR B 1 249 ? 142.878 100.767 159.665 1.00 84.04  ? 249 THR D OG1   1 
ATOM   3935 C CG2   . THR B 1 249 ? 143.768 102.751 160.699 1.00 74.25  ? 249 THR D CG2   1 
ATOM   3936 N N     . LEU B 1 250 ? 141.573 104.171 162.237 1.00 66.01  ? 250 LEU D N     1 
ATOM   3937 C CA    . LEU B 1 250 ? 141.177 105.521 162.622 1.00 64.30  ? 250 LEU D CA    1 
ATOM   3938 C C     . LEU B 1 250 ? 141.272 106.476 161.440 1.00 60.13  ? 250 LEU D C     1 
ATOM   3939 O O     . LEU B 1 250 ? 140.358 107.272 161.191 1.00 61.71  ? 250 LEU D O     1 
ATOM   3940 C CB    . LEU B 1 250 ? 142.048 106.009 163.779 1.00 63.70  ? 250 LEU D CB    1 
ATOM   3941 C CG    . LEU B 1 250 ? 141.855 107.466 164.203 1.00 64.05  ? 250 LEU D CG    1 
ATOM   3942 C CD1   . LEU B 1 250 ? 140.395 107.761 164.488 1.00 61.65  ? 250 LEU D CD1   1 
ATOM   3943 C CD2   . LEU B 1 250 ? 142.703 107.773 165.420 1.00 68.18  ? 250 LEU D CD2   1 
ATOM   3944 N N     . ARG B 1 251 ? 142.373 106.405 160.692 1.00 56.52  ? 251 ARG D N     1 
ATOM   3945 C CA    . ARG B 1 251 ? 142.580 107.343 159.595 1.00 56.66  ? 251 ARG D CA    1 
ATOM   3946 C C     . ARG B 1 251 ? 141.512 107.180 158.521 1.00 55.25  ? 251 ARG D C     1 
ATOM   3947 O O     . ARG B 1 251 ? 140.952 108.166 158.030 1.00 57.49  ? 251 ARG D O     1 
ATOM   3948 C CB    . ARG B 1 251 ? 143.974 107.146 159.003 1.00 55.94  ? 251 ARG D CB    1 
ATOM   3949 C CG    . ARG B 1 251 ? 144.979 108.200 159.415 1.00 56.84  ? 251 ARG D CG    1 
ATOM   3950 C CD    . ARG B 1 251 ? 146.298 107.997 158.695 1.00 58.44  ? 251 ARG D CD    1 
ATOM   3951 N NE    . ARG B 1 251 ? 146.359 108.746 157.446 1.00 60.33  ? 251 ARG D NE    1 
ATOM   3952 C CZ    . ARG B 1 251 ? 147.138 108.433 156.419 1.00 64.36  ? 251 ARG D CZ    1 
ATOM   3953 N NH1   . ARG B 1 251 ? 147.944 107.384 156.455 1.00 62.82  ? 251 ARG D NH1   1 
ATOM   3954 N NH2   . ARG B 1 251 ? 147.107 109.192 155.328 1.00 64.85  ? 251 ARG D NH2   1 
ATOM   3955 N N     . GLU B 1 252 ? 141.214 105.937 158.139 1.00 56.54  ? 252 GLU D N     1 
ATOM   3956 C CA    . GLU B 1 252 ? 140.252 105.721 157.065 1.00 53.42  ? 252 GLU D CA    1 
ATOM   3957 C C     . GLU B 1 252 ? 138.848 106.134 157.491 1.00 52.95  ? 252 GLU D C     1 
ATOM   3958 O O     . GLU B 1 252 ? 138.107 106.731 156.702 1.00 52.75  ? 252 GLU D O     1 
ATOM   3959 C CB    . GLU B 1 252 ? 140.294 104.262 156.611 1.00 56.71  ? 252 GLU D CB    1 
ATOM   3960 C CG    . GLU B 1 252 ? 139.283 103.345 157.262 1.00 62.06  ? 252 GLU D CG    1 
ATOM   3961 C CD    . GLU B 1 252 ? 139.544 101.887 156.935 1.00 68.03  ? 252 GLU D CD    1 
ATOM   3962 O OE1   . GLU B 1 252 ? 140.439 101.615 156.109 1.00 65.80  ? 252 GLU D OE1   1 
ATOM   3963 O OE2   . GLU B 1 252 ? 138.853 101.015 157.499 1.00 73.99  ? 252 GLU D OE2   1 
ATOM   3964 N N     . LEU B 1 253 ? 138.467 105.848 158.736 1.00 52.32  ? 253 LEU D N     1 
ATOM   3965 C CA    . LEU B 1 253 ? 137.166 106.295 159.225 1.00 52.41  ? 253 LEU D CA    1 
ATOM   3966 C C     . LEU B 1 253 ? 137.082 107.816 159.236 1.00 54.37  ? 253 LEU D C     1 
ATOM   3967 O O     . LEU B 1 253 ? 136.075 108.401 158.813 1.00 54.90  ? 253 LEU D O     1 
ATOM   3968 C CB    . LEU B 1 253 ? 136.914 105.734 160.624 1.00 52.38  ? 253 LEU D CB    1 
ATOM   3969 C CG    . LEU B 1 253 ? 135.889 106.464 161.493 1.00 53.72  ? 253 LEU D CG    1 
ATOM   3970 C CD1   . LEU B 1 253 ? 134.520 106.472 160.841 1.00 53.58  ? 253 LEU D CD1   1 
ATOM   3971 C CD2   . LEU B 1 253 ? 135.827 105.816 162.859 1.00 64.71  ? 253 LEU D CD2   1 
ATOM   3972 N N     . LEU B 1 254 ? 138.136 108.476 159.721 1.00 53.70  ? 254 LEU D N     1 
ATOM   3973 C CA    . LEU B 1 254 ? 138.129 109.933 159.764 1.00 49.57  ? 254 LEU D CA    1 
ATOM   3974 C C     . LEU B 1 254 ? 138.026 110.516 158.363 1.00 46.74  ? 254 LEU D C     1 
ATOM   3975 O O     . LEU B 1 254 ? 137.331 111.515 158.148 1.00 52.63  ? 254 LEU D O     1 
ATOM   3976 C CB    . LEU B 1 254 ? 139.383 110.441 160.470 1.00 49.40  ? 254 LEU D CB    1 
ATOM   3977 C CG    . LEU B 1 254 ? 139.405 110.193 161.976 1.00 53.14  ? 254 LEU D CG    1 
ATOM   3978 C CD1   . LEU B 1 254 ? 140.783 110.471 162.539 1.00 56.39  ? 254 LEU D CD1   1 
ATOM   3979 C CD2   . LEU B 1 254 ? 138.361 111.045 162.670 1.00 53.26  ? 254 LEU D CD2   1 
ATOM   3980 N N     . ALA B 1 255 ? 138.708 109.906 157.396 1.00 41.56  ? 255 ALA D N     1 
ATOM   3981 C CA    . ALA B 1 255 ? 138.558 110.338 156.012 1.00 43.45  ? 255 ALA D CA    1 
ATOM   3982 C C     . ALA B 1 255 ? 137.131 110.125 155.527 1.00 44.29  ? 255 ALA D C     1 
ATOM   3983 O O     . ALA B 1 255 ? 136.589 110.952 154.786 1.00 44.79  ? 255 ALA D O     1 
ATOM   3984 C CB    . ALA B 1 255 ? 139.544 109.589 155.121 1.00 44.67  ? 255 ALA D CB    1 
ATOM   3985 N N     . SER B 1 256 ? 136.507 109.016 155.931 1.00 44.09  ? 256 SER D N     1 
ATOM   3986 C CA    . SER B 1 256 ? 135.141 108.735 155.503 1.00 44.57  ? 256 SER D CA    1 
ATOM   3987 C C     . SER B 1 256 ? 134.174 109.800 156.003 1.00 48.28  ? 256 SER D C     1 
ATOM   3988 O O     . SER B 1 256 ? 133.322 110.282 155.250 1.00 49.89  ? 256 SER D O     1 
ATOM   3989 C CB    . SER B 1 256 ? 134.712 107.357 156.001 1.00 46.07  ? 256 SER D CB    1 
ATOM   3990 O OG    . SER B 1 256 ? 135.771 106.427 155.899 1.00 50.97  ? 256 SER D OG    1 
ATOM   3991 N N     . ILE B 1 257 ? 134.292 110.183 157.273 1.00 50.34  ? 257 ILE D N     1 
ATOM   3992 C CA    . ILE B 1 257 ? 133.323 111.110 157.852 1.00 48.92  ? 257 ILE D CA    1 
ATOM   3993 C C     . ILE B 1 257 ? 133.771 112.568 157.742 1.00 49.49  ? 257 ILE D C     1 
ATOM   3994 O O     . ILE B 1 257 ? 132.927 113.463 157.640 1.00 54.04  ? 257 ILE D O     1 
ATOM   3995 C CB    . ILE B 1 257 ? 133.029 110.738 159.316 1.00 45.34  ? 257 ILE D CB    1 
ATOM   3996 C CG1   . ILE B 1 257 ? 134.281 110.884 160.180 1.00 47.25  ? 257 ILE D CG1   1 
ATOM   3997 C CG2   . ILE B 1 257 ? 132.494 109.320 159.405 1.00 49.01  ? 257 ILE D CG2   1 
ATOM   3998 C CD1   . ILE B 1 257 ? 134.062 110.514 161.626 1.00 54.33  ? 257 ILE D CD1   1 
ATOM   3999 N N     . ALA B 1 258 ? 135.073 112.831 157.754 1.00 43.17  ? 258 ALA D N     1 
ATOM   4000 C CA    . ALA B 1 258 ? 135.589 114.194 157.713 1.00 41.19  ? 258 ALA D CA    1 
ATOM   4001 C C     . ALA B 1 258 ? 136.917 114.175 156.971 1.00 39.08  ? 258 ALA D C     1 
ATOM   4002 O O     . ALA B 1 258 ? 137.242 113.205 156.281 1.00 48.13  ? 258 ALA D O     1 
ATOM   4003 C CB    . ALA B 1 258 ? 135.722 114.760 159.130 1.00 49.46  ? 258 ALA D CB    1 
ATOM   4004 N N     . TRP B 1 259 ? 137.689 115.253 157.099 1.00 38.98  ? 259 TRP D N     1 
ATOM   4005 C CA    . TRP B 1 259 ? 138.994 115.331 156.453 1.00 43.83  ? 259 TRP D CA    1 
ATOM   4006 C C     . TRP B 1 259 ? 139.982 115.981 157.416 1.00 41.66  ? 259 TRP D C     1 
ATOM   4007 O O     . TRP B 1 259 ? 139.710 116.133 158.610 1.00 48.09  ? 259 TRP D O     1 
ATOM   4008 C CB    . TRP B 1 259 ? 138.895 116.063 155.108 1.00 50.62  ? 259 TRP D CB    1 
ATOM   4009 C CG    . TRP B 1 259 ? 138.280 117.420 155.145 1.00 49.87  ? 259 TRP D CG    1 
ATOM   4010 C CD1   . TRP B 1 259 ? 136.980 117.724 155.408 1.00 46.62  ? 259 TRP D CD1   1 
ATOM   4011 C CD2   . TRP B 1 259 ? 138.936 118.662 154.870 1.00 53.32  ? 259 TRP D CD2   1 
ATOM   4012 N NE1   . TRP B 1 259 ? 136.786 119.080 155.327 1.00 46.79  ? 259 TRP D NE1   1 
ATOM   4013 C CE2   . TRP B 1 259 ? 137.973 119.679 154.998 1.00 52.33  ? 259 TRP D CE2   1 
ATOM   4014 C CE3   . TRP B 1 259 ? 140.246 119.013 154.535 1.00 53.38  ? 259 TRP D CE3   1 
ATOM   4015 C CZ2   . TRP B 1 259 ? 138.278 121.021 154.806 1.00 58.62  ? 259 TRP D CZ2   1 
ATOM   4016 C CZ3   . TRP B 1 259 ? 140.546 120.346 154.345 1.00 53.89  ? 259 TRP D CZ3   1 
ATOM   4017 C CH2   . TRP B 1 259 ? 139.568 121.333 154.480 1.00 58.47  ? 259 TRP D CH2   1 
ATOM   4018 N N     . GLY B 1 260 ? 141.146 116.360 156.888 1.00 41.93  ? 260 GLY D N     1 
ATOM   4019 C CA    . GLY B 1 260 ? 142.261 116.722 157.749 1.00 48.78  ? 260 GLY D CA    1 
ATOM   4020 C C     . GLY B 1 260 ? 141.985 117.926 158.626 1.00 59.23  ? 260 GLY D C     1 
ATOM   4021 O O     . GLY B 1 260 ? 142.373 117.953 159.796 1.00 63.04  ? 260 GLY D O     1 
ATOM   4022 N N     . LEU B 1 261 ? 141.323 118.939 158.079 1.00 63.34  ? 261 LEU D N     1 
ATOM   4023 C CA    . LEU B 1 261 ? 141.135 120.204 158.776 1.00 62.49  ? 261 LEU D CA    1 
ATOM   4024 C C     . LEU B 1 261 ? 139.828 120.283 159.553 1.00 61.25  ? 261 LEU D C     1 
ATOM   4025 O O     . LEU B 1 261 ? 139.521 121.344 160.102 1.00 74.50  ? 261 LEU D O     1 
ATOM   4026 C CB    . LEU B 1 261 ? 141.198 121.367 157.783 1.00 66.70  ? 261 LEU D CB    1 
ATOM   4027 C CG    . LEU B 1 261 ? 142.574 121.688 157.200 1.00 69.94  ? 261 LEU D CG    1 
ATOM   4028 C CD1   . LEU B 1 261 ? 142.490 122.886 156.274 1.00 70.23  ? 261 LEU D CD1   1 
ATOM   4029 C CD2   . LEU B 1 261 ? 143.573 121.946 158.308 1.00 69.03  ? 261 LEU D CD2   1 
ATOM   4030 N N     . CYS B 1 262 ? 139.046 119.213 159.612 1.00 56.33  ? 262 CYS D N     1 
ATOM   4031 C CA    . CYS B 1 262 ? 137.857 119.237 160.446 1.00 54.96  ? 262 CYS D CA    1 
ATOM   4032 C C     . CYS B 1 262 ? 138.249 119.119 161.918 1.00 60.58  ? 262 CYS D C     1 
ATOM   4033 O O     . CYS B 1 262 ? 139.415 118.919 162.271 1.00 64.56  ? 262 CYS D O     1 
ATOM   4034 C CB    . CYS B 1 262 ? 136.898 118.118 160.051 1.00 55.93  ? 262 CYS D CB    1 
ATOM   4035 S SG    . CYS B 1 262 ? 135.516 118.659 159.016 1.00 61.44  ? 262 CYS D SG    1 
ATOM   4036 N N     . ASP B 1 263 ? 137.253 119.253 162.788 1.00 66.09  ? 263 ASP D N     1 
ATOM   4037 C CA    . ASP B 1 263 ? 137.509 119.248 164.221 1.00 70.77  ? 263 ASP D CA    1 
ATOM   4038 C C     . ASP B 1 263 ? 138.032 117.891 164.672 1.00 69.15  ? 263 ASP D C     1 
ATOM   4039 O O     . ASP B 1 263 ? 137.762 116.858 164.055 1.00 67.83  ? 263 ASP D O     1 
ATOM   4040 C CB    . ASP B 1 263 ? 136.233 119.593 164.990 1.00 72.37  ? 263 ASP D CB    1 
ATOM   4041 C CG    . ASP B 1 263 ? 136.499 119.888 166.450 1.00 73.98  ? 263 ASP D CG    1 
ATOM   4042 O OD1   . ASP B 1 263 ? 136.711 118.930 167.221 1.00 71.77  ? 263 ASP D OD1   1 
ATOM   4043 O OD2   . ASP B 1 263 ? 136.497 121.078 166.828 1.00 81.51  ? 263 ASP D OD2   1 
ATOM   4044 N N     . GLY B 1 264 ? 138.800 117.902 165.766 1.00 71.70  ? 264 GLY D N     1 
ATOM   4045 C CA    . GLY B 1 264 ? 139.304 116.664 166.331 1.00 68.90  ? 264 GLY D CA    1 
ATOM   4046 C C     . GLY B 1 264 ? 138.281 115.878 167.116 1.00 69.45  ? 264 GLY D C     1 
ATOM   4047 O O     . GLY B 1 264 ? 138.503 114.695 167.393 1.00 71.88  ? 264 GLY D O     1 
ATOM   4048 N N     . VAL B 1 265 ? 137.155 116.504 167.467 1.00 71.31  ? 265 VAL D N     1 
ATOM   4049 C CA    . VAL B 1 265 ? 136.132 115.817 168.250 1.00 73.79  ? 265 VAL D CA    1 
ATOM   4050 C C     . VAL B 1 265 ? 135.624 114.589 167.513 1.00 72.86  ? 265 VAL D C     1 
ATOM   4051 O O     . VAL B 1 265 ? 135.165 113.626 168.139 1.00 75.03  ? 265 VAL D O     1 
ATOM   4052 C CB    . VAL B 1 265 ? 134.979 116.782 168.583 1.00 78.29  ? 265 VAL D CB    1 
ATOM   4053 C CG1   . VAL B 1 265 ? 134.241 117.193 167.317 1.00 77.51  ? 265 VAL D CG1   1 
ATOM   4054 C CG2   . VAL B 1 265 ? 134.023 116.139 169.572 1.00 82.48  ? 265 VAL D CG2   1 
ATOM   4055 N N     . LEU B 1 266 ? 135.693 114.595 166.182 1.00 66.08  ? 266 LEU D N     1 
ATOM   4056 C CA    . LEU B 1 266 ? 135.219 113.452 165.414 1.00 64.42  ? 266 LEU D CA    1 
ATOM   4057 C C     . LEU B 1 266 ? 135.999 112.187 165.738 1.00 67.07  ? 266 LEU D C     1 
ATOM   4058 O O     . LEU B 1 266 ? 135.518 111.086 165.451 1.00 66.95  ? 266 LEU D O     1 
ATOM   4059 C CB    . LEU B 1 266 ? 135.302 113.758 163.921 1.00 62.20  ? 266 LEU D CB    1 
ATOM   4060 C CG    . LEU B 1 266 ? 134.450 114.948 163.478 1.00 62.36  ? 266 LEU D CG    1 
ATOM   4061 C CD1   . LEU B 1 266 ? 135.078 115.640 162.287 1.00 60.72  ? 266 LEU D CD1   1 
ATOM   4062 C CD2   . LEU B 1 266 ? 133.037 114.505 163.155 1.00 65.39  ? 266 LEU D CD2   1 
ATOM   4063 N N     . ALA B 1 267 ? 137.185 112.315 166.335 1.00 71.35  ? 267 ALA D N     1 
ATOM   4064 C CA    . ALA B 1 267 ? 137.917 111.132 166.769 1.00 69.34  ? 267 ALA D CA    1 
ATOM   4065 C C     . ALA B 1 267 ? 137.124 110.313 167.776 1.00 72.08  ? 267 ALA D C     1 
ATOM   4066 O O     . ALA B 1 267 ? 137.394 109.119 167.938 1.00 72.50  ? 267 ALA D O     1 
ATOM   4067 C CB    . ALA B 1 267 ? 139.264 111.536 167.370 1.00 70.43  ? 267 ALA D CB    1 
ATOM   4068 N N     . GLU B 1 268 ? 136.151 110.927 168.454 1.00 76.75  ? 268 GLU D N     1 
ATOM   4069 C CA    . GLU B 1 268 ? 135.295 110.201 169.384 1.00 80.50  ? 268 GLU D CA    1 
ATOM   4070 C C     . GLU B 1 268 ? 134.362 109.225 168.681 1.00 78.73  ? 268 GLU D C     1 
ATOM   4071 O O     . GLU B 1 268 ? 133.730 108.407 169.356 1.00 76.64  ? 268 GLU D O     1 
ATOM   4072 C CB    . GLU B 1 268 ? 134.472 111.183 170.217 1.00 79.43  ? 268 GLU D CB    1 
ATOM   4073 C CG    . GLU B 1 268 ? 133.973 110.607 171.532 1.00 80.72  ? 268 GLU D CG    1 
ATOM   4074 C CD    . GLU B 1 268 ? 135.049 110.575 172.598 1.00 83.67  ? 268 GLU D CD    1 
ATOM   4075 O OE1   . GLU B 1 268 ? 136.241 110.681 172.242 1.00 85.58  ? 268 GLU D OE1   1 
ATOM   4076 O OE2   . GLU B 1 268 ? 134.703 110.444 173.791 1.00 83.18  ? 268 GLU D OE2   1 
ATOM   4077 N N     . CYS B 1 269 ? 134.254 109.292 167.356 1.00 76.02  ? 269 CYS D N     1 
ATOM   4078 C CA    . CYS B 1 269 ? 133.479 108.322 166.597 1.00 75.72  ? 269 CYS D CA    1 
ATOM   4079 C C     . CYS B 1 269 ? 134.205 106.994 166.439 1.00 79.82  ? 269 CYS D C     1 
ATOM   4080 O O     . CYS B 1 269 ? 133.672 106.085 165.795 1.00 81.73  ? 269 CYS D O     1 
ATOM   4081 C CB    . CYS B 1 269 ? 133.137 108.889 165.218 1.00 70.00  ? 269 CYS D CB    1 
ATOM   4082 S SG    . CYS B 1 269 ? 132.331 110.501 165.271 1.00 76.22  ? 269 CYS D SG    1 
ATOM   4083 N N     . TRP B 1 270 ? 135.397 106.864 167.015 1.00 78.79  ? 270 TRP D N     1 
ATOM   4084 C CA    . TRP B 1 270 ? 136.210 105.665 166.902 1.00 76.09  ? 270 TRP D CA    1 
ATOM   4085 C C     . TRP B 1 270 ? 136.581 105.171 168.292 1.00 79.31  ? 270 TRP D C     1 
ATOM   4086 O O     . TRP B 1 270 ? 136.628 105.945 169.252 1.00 73.43  ? 270 TRP D O     1 
ATOM   4087 C CB    . TRP B 1 270 ? 137.476 105.938 166.087 1.00 73.00  ? 270 TRP D CB    1 
ATOM   4088 C CG    . TRP B 1 270 ? 138.190 104.707 165.644 1.00 74.34  ? 270 TRP D CG    1 
ATOM   4089 C CD1   . TRP B 1 270 ? 137.722 103.749 164.799 1.00 72.74  ? 270 TRP D CD1   1 
ATOM   4090 C CD2   . TRP B 1 270 ? 139.511 104.302 166.021 1.00 82.05  ? 270 TRP D CD2   1 
ATOM   4091 N NE1   . TRP B 1 270 ? 138.669 102.769 164.625 1.00 75.40  ? 270 TRP D NE1   1 
ATOM   4092 C CE2   . TRP B 1 270 ? 139.777 103.085 165.365 1.00 79.73  ? 270 TRP D CE2   1 
ATOM   4093 C CE3   . TRP B 1 270 ? 140.494 104.849 166.851 1.00 81.16  ? 270 TRP D CE3   1 
ATOM   4094 C CZ2   . TRP B 1 270 ? 140.984 102.407 165.512 1.00 82.90  ? 270 TRP D CZ2   1 
ATOM   4095 C CZ3   . TRP B 1 270 ? 141.691 104.174 166.995 1.00 79.97  ? 270 TRP D CZ3   1 
ATOM   4096 C CH2   . TRP B 1 270 ? 141.925 102.966 166.329 1.00 86.04  ? 270 TRP D CH2   1 
ATOM   4097 N N     . SER B 1 271 ? 136.843 103.872 168.390 1.00 86.16  ? 271 SER D N     1 
ATOM   4098 C CA    . SER B 1 271 ? 137.219 103.255 169.655 1.00 82.84  ? 271 SER D CA    1 
ATOM   4099 C C     . SER B 1 271 ? 138.121 102.053 169.401 1.00 82.91  ? 271 SER D C     1 
ATOM   4100 O O     . SER B 1 271 ? 137.696 101.092 168.748 1.00 85.63  ? 271 SER D O     1 
ATOM   4101 C CB    . SER B 1 271 ? 135.976 102.825 170.434 1.00 85.15  ? 271 SER D CB    1 
ATOM   4102 O OG    . SER B 1 271 ? 136.314 102.444 171.756 1.00 92.98  ? 271 SER D OG    1 
ATOM   4103 N N     . PRO B 1 272 ? 139.359 102.056 169.893 1.00 81.61  ? 272 PRO D N     1 
ATOM   4104 C CA    . PRO B 1 272 ? 140.238 100.908 169.649 1.00 87.17  ? 272 PRO D CA    1 
ATOM   4105 C C     . PRO B 1 272 ? 139.634 99.621  170.190 1.00 95.49  ? 272 PRO D C     1 
ATOM   4106 O O     . PRO B 1 272 ? 138.958 99.614  171.221 1.00 94.91  ? 272 PRO D O     1 
ATOM   4107 C CB    . PRO B 1 272 ? 141.527 101.279 170.390 1.00 91.51  ? 272 PRO D CB    1 
ATOM   4108 C CG    . PRO B 1 272 ? 141.496 102.755 170.507 1.00 89.00  ? 272 PRO D CG    1 
ATOM   4109 C CD    . PRO B 1 272 ? 140.057 103.145 170.599 1.00 84.45  ? 272 PRO D CD    1 
ATOM   4110 N N     . SER B 1 273 ? 139.879 98.527  169.475 1.00 105.13 ? 273 SER D N     1 
ATOM   4111 C CA    . SER B 1 273 ? 139.401 97.219  169.890 1.00 111.37 ? 273 SER D CA    1 
ATOM   4112 C C     . SER B 1 273 ? 140.383 96.597  170.883 1.00 115.79 ? 273 SER D C     1 
ATOM   4113 O O     . SER B 1 273 ? 141.351 97.224  171.321 1.00 116.24 ? 273 SER D O     1 
ATOM   4114 C CB    . SER B 1 273 ? 139.197 96.323  168.669 1.00 110.61 ? 273 SER D CB    1 
ATOM   4115 O OG    . SER B 1 273 ? 137.891 96.477  168.140 1.00 105.50 ? 273 SER D OG    1 
ATOM   4116 N N     . GLN B 1 274 ? 140.125 95.343  171.248 1.00 120.01 ? 274 GLN D N     1 
ATOM   4117 C CA    . GLN B 1 274 ? 140.998 94.641  172.177 1.00 124.46 ? 274 GLN D CA    1 
ATOM   4118 C C     . GLN B 1 274 ? 142.415 94.559  171.621 1.00 127.58 ? 274 GLN D C     1 
ATOM   4119 O O     . GLN B 1 274 ? 142.621 94.334  170.426 1.00 125.73 ? 274 GLN D O     1 
ATOM   4120 C CB    . GLN B 1 274 ? 140.461 93.234  172.444 1.00 120.47 ? 274 GLN D CB    1 
ATOM   4121 C CG    . GLN B 1 274 ? 139.083 93.203  173.086 1.00 119.99 ? 274 GLN D CG    1 
ATOM   4122 C CD    . GLN B 1 274 ? 138.361 91.891  172.850 1.00 125.18 ? 274 GLN D CD    1 
ATOM   4123 O OE1   . GLN B 1 274 ? 138.939 90.936  172.330 1.00 126.37 ? 274 GLN D OE1   1 
ATOM   4124 N NE2   . GLN B 1 274 ? 137.089 91.838  173.228 1.00 124.80 ? 274 GLN D NE2   1 
ATOM   4125 N N     . GLY B 1 275 ? 143.396 94.746  172.501 1.00 124.84 ? 275 GLY D N     1 
ATOM   4126 C CA    . GLY B 1 275 ? 144.785 94.625  172.107 1.00 120.27 ? 275 GLY D CA    1 
ATOM   4127 C C     . GLY B 1 275 ? 145.341 95.806  171.349 1.00 118.91 ? 275 GLY D C     1 
ATOM   4128 O O     . GLY B 1 275 ? 146.390 95.674  170.710 1.00 117.42 ? 275 GLY D O     1 
ATOM   4129 N N     . ASP B 1 276 ? 144.674 96.958  171.395 1.00 120.37 ? 276 ASP D N     1 
ATOM   4130 C CA    . ASP B 1 276 ? 145.163 98.151  170.713 1.00 122.24 ? 276 ASP D CA    1 
ATOM   4131 C C     . ASP B 1 276 ? 145.288 97.892  169.215 1.00 123.64 ? 276 ASP D C     1 
ATOM   4132 O O     . ASP B 1 276 ? 144.308 98.025  168.476 1.00 116.51 ? 276 ASP D O     1 
ATOM   4133 C CB    . ASP B 1 276 ? 146.503 98.594  171.310 1.00 121.79 ? 276 ASP D CB    1 
ATOM   4134 C CG    . ASP B 1 276 ? 147.050 99.852  170.659 1.00 122.69 ? 276 ASP D CG    1 
ATOM   4135 O OD1   . ASP B 1 276 ? 146.345 100.450 169.819 1.00 126.24 ? 276 ASP D OD1   1 
ATOM   4136 O OD2   . ASP B 1 276 ? 148.189 100.244 170.988 1.00 122.63 ? 276 ASP D OD2   1 
ATOM   4137 N N     . GLY B 1 277 ? 146.486 97.526  168.757 1.00 122.97 ? 277 GLY D N     1 
ATOM   4138 C CA    . GLY B 1 277 ? 146.677 97.268  167.345 1.00 115.66 ? 277 GLY D CA    1 
ATOM   4139 C C     . GLY B 1 277 ? 146.488 98.524  166.512 1.00 109.44 ? 277 GLY D C     1 
ATOM   4140 O O     . GLY B 1 277 ? 146.749 99.648  166.952 1.00 103.89 ? 277 GLY D O     1 
ATOM   4141 N N     . SER B 1 278 ? 146.024 98.323  165.277 1.00 109.34 ? 278 SER D N     1 
ATOM   4142 C CA    . SER B 1 278 ? 145.784 99.414  164.346 1.00 107.97 ? 278 SER D CA    1 
ATOM   4143 C C     . SER B 1 278 ? 144.340 99.526  163.882 1.00 102.47 ? 278 SER D C     1 
ATOM   4144 O O     . SER B 1 278 ? 143.943 100.606 163.434 1.00 99.41  ? 278 SER D O     1 
ATOM   4145 C CB    . SER B 1 278 ? 146.682 99.267  163.106 1.00 106.72 ? 278 SER D CB    1 
ATOM   4146 O OG    . SER B 1 278 ? 146.804 97.908  162.725 1.00 114.81 ? 278 SER D OG    1 
ATOM   4147 N N     . ILE B 1 279 ? 143.549 98.460  163.979 1.00 99.90  ? 279 ILE D N     1 
ATOM   4148 C CA    . ILE B 1 279 ? 142.170 98.444  163.504 1.00 92.92  ? 279 ILE D CA    1 
ATOM   4149 C C     . ILE B 1 279 ? 141.243 98.412  164.710 1.00 90.11  ? 279 ILE D C     1 
ATOM   4150 O O     . ILE B 1 279 ? 141.373 97.540  165.579 1.00 89.64  ? 279 ILE D O     1 
ATOM   4151 C CB    . ILE B 1 279 ? 141.911 97.244  162.577 1.00 92.77  ? 279 ILE D CB    1 
ATOM   4152 C CG1   . ILE B 1 279 ? 142.504 97.513  161.192 1.00 91.75  ? 279 ILE D CG1   1 
ATOM   4153 C CG2   . ILE B 1 279 ? 140.417 96.956  162.475 1.00 91.59  ? 279 ILE D CG2   1 
ATOM   4154 C CD1   . ILE B 1 279 ? 142.685 96.270  160.350 1.00 97.84  ? 279 ILE D CD1   1 
ATOM   4155 N N     . GLY B 1 280 ? 140.308 99.358  164.759 1.00 84.14  ? 280 GLY D N     1 
ATOM   4156 C CA    . GLY B 1 280 ? 139.365 99.447  165.856 1.00 82.95  ? 280 GLY D CA    1 
ATOM   4157 C C     . GLY B 1 280 ? 137.947 99.117  165.443 1.00 83.83  ? 280 GLY D C     1 
ATOM   4158 O O     . GLY B 1 280 ? 137.693 98.052  164.875 1.00 86.42  ? 280 GLY D O     1 
ATOM   4159 N N     . VAL B 1 281 ? 137.010 100.024 165.728 1.00 81.08  ? 281 VAL D N     1 
ATOM   4160 C CA    . VAL B 1 281 ? 135.604 99.827  165.397 1.00 78.65  ? 281 VAL D CA    1 
ATOM   4161 C C     . VAL B 1 281 ? 134.911 101.181 165.395 1.00 78.00  ? 281 VAL D C     1 
ATOM   4162 O O     . VAL B 1 281 ? 135.312 102.109 166.099 1.00 79.96  ? 281 VAL D O     1 
ATOM   4163 C CB    . VAL B 1 281 ? 134.910 98.863  166.388 1.00 79.21  ? 281 VAL D CB    1 
ATOM   4164 C CG1   . VAL B 1 281 ? 134.781 99.509  167.759 1.00 79.77  ? 281 VAL D CG1   1 
ATOM   4165 C CG2   . VAL B 1 281 ? 133.553 98.441  165.858 1.00 79.52  ? 281 VAL D CG2   1 
ATOM   4166 N N     . VAL B 1 282 ? 133.857 101.289 164.593 1.00 81.17  ? 282 VAL D N     1 
ATOM   4167 C CA    . VAL B 1 282 ? 133.058 102.507 164.512 1.00 81.02  ? 282 VAL D CA    1 
ATOM   4168 C C     . VAL B 1 282 ? 132.037 102.493 165.639 1.00 84.42  ? 282 VAL D C     1 
ATOM   4169 O O     . VAL B 1 282 ? 131.329 101.498 165.835 1.00 89.73  ? 282 VAL D O     1 
ATOM   4170 C CB    . VAL B 1 282 ? 132.363 102.624 163.145 1.00 78.32  ? 282 VAL D CB    1 
ATOM   4171 C CG1   . VAL B 1 282 ? 131.610 103.942 163.043 1.00 75.23  ? 282 VAL D CG1   1 
ATOM   4172 C CG2   . VAL B 1 282 ? 133.373 102.495 162.021 1.00 74.78  ? 282 VAL D CG2   1 
ATOM   4173 N N     . VAL B 1 283 ? 131.959 103.594 166.381 1.00 81.97  ? 283 VAL D N     1 
ATOM   4174 C CA    . VAL B 1 283 ? 131.026 103.705 167.492 1.00 86.11  ? 283 VAL D CA    1 
ATOM   4175 C C     . VAL B 1 283 ? 129.936 104.739 167.239 1.00 86.86  ? 283 VAL D C     1 
ATOM   4176 O O     . VAL B 1 283 ? 128.893 104.689 167.909 1.00 93.87  ? 283 VAL D O     1 
ATOM   4177 C CB    . VAL B 1 283 ? 131.768 104.022 168.807 1.00 90.83  ? 283 VAL D CB    1 
ATOM   4178 C CG1   . VAL B 1 283 ? 130.785 104.173 169.957 1.00 91.18  ? 283 VAL D CG1   1 
ATOM   4179 C CG2   . VAL B 1 283 ? 132.789 102.936 169.113 1.00 86.35  ? 283 VAL D CG2   1 
ATOM   4180 N N     . GLY B 1 284 ? 130.127 105.659 166.298 1.00 81.58  ? 284 GLY D N     1 
ATOM   4181 C CA    . GLY B 1 284 ? 129.109 106.647 166.001 1.00 81.70  ? 284 GLY D CA    1 
ATOM   4182 C C     . GLY B 1 284 ? 129.309 107.238 164.626 1.00 78.53  ? 284 GLY D C     1 
ATOM   4183 O O     . GLY B 1 284 ? 130.380 107.116 164.024 1.00 79.82  ? 284 GLY D O     1 
ATOM   4184 N N     . LEU B 1 285 ? 128.257 107.878 164.130 1.00 78.81  ? 285 LEU D N     1 
ATOM   4185 C CA    . LEU B 1 285 ? 128.281 108.545 162.829 1.00 75.34  ? 285 LEU D CA    1 
ATOM   4186 C C     . LEU B 1 285 ? 127.661 109.927 162.982 1.00 74.91  ? 285 LEU D C     1 
ATOM   4187 O O     . LEU B 1 285 ? 126.430 110.031 163.163 1.00 82.42  ? 285 LEU D O     1 
ATOM   4188 C CB    . LEU B 1 285 ? 127.533 107.727 161.780 1.00 80.26  ? 285 LEU D CB    1 
ATOM   4189 C CG    . LEU B 1 285 ? 128.113 106.347 161.467 1.00 79.61  ? 285 LEU D CG    1 
ATOM   4190 C CD1   . LEU B 1 285 ? 127.217 105.614 160.482 1.00 80.19  ? 285 LEU D CD1   1 
ATOM   4191 C CD2   . LEU B 1 285 ? 129.533 106.452 160.930 1.00 76.01  ? 285 LEU D CD2   1 
ATOM   4192 N N     . PRO B 1 286 ? 128.446 111.001 162.918 1.00 69.13  ? 286 PRO D N     1 
ATOM   4193 C CA    . PRO B 1 286 ? 127.888 112.336 163.153 1.00 75.34  ? 286 PRO D CA    1 
ATOM   4194 C C     . PRO B 1 286 ? 126.747 112.666 162.202 1.00 77.52  ? 286 PRO D C     1 
ATOM   4195 O O     . PRO B 1 286 ? 126.468 111.949 161.238 1.00 75.29  ? 286 PRO D O     1 
ATOM   4196 C CB    . PRO B 1 286 ? 129.085 113.264 162.924 1.00 71.96  ? 286 PRO D CB    1 
ATOM   4197 C CG    . PRO B 1 286 ? 130.267 112.427 163.208 1.00 69.28  ? 286 PRO D CG    1 
ATOM   4198 C CD    . PRO B 1 286 ? 129.909 111.043 162.760 1.00 71.52  ? 286 PRO D CD    1 
ATOM   4199 N N     . LEU B 1 287 ? 126.076 113.776 162.500 1.00 81.67  ? 287 LEU D N     1 
ATOM   4200 C CA    . LEU B 1 287 ? 125.018 114.324 161.666 1.00 82.24  ? 287 LEU D CA    1 
ATOM   4201 C C     . LEU B 1 287 ? 125.328 115.782 161.358 1.00 81.05  ? 287 LEU D C     1 
ATOM   4202 O O     . LEU B 1 287 ? 125.851 116.512 162.205 1.00 79.16  ? 287 LEU D O     1 
ATOM   4203 C CB    . LEU B 1 287 ? 123.653 114.215 162.353 1.00 84.93  ? 287 LEU D CB    1 
ATOM   4204 C CG    . LEU B 1 287 ? 123.160 112.793 162.633 1.00 86.25  ? 287 LEU D CG    1 
ATOM   4205 C CD1   . LEU B 1 287 ? 121.920 112.824 163.513 1.00 85.96  ? 287 LEU D CD1   1 
ATOM   4206 C CD2   . LEU B 1 287 ? 122.880 112.054 161.335 1.00 85.41  ? 287 LEU D CD2   1 
ATOM   4207 N N     . GLN B 1 288 ? 124.998 116.203 160.139 1.00 85.16  ? 288 GLN D N     1 
ATOM   4208 C CA    . GLN B 1 288 ? 125.327 117.538 159.643 1.00 85.66  ? 288 GLN D CA    1 
ATOM   4209 C C     . GLN B 1 288 ? 124.073 118.247 159.144 1.00 89.94  ? 288 GLN D C     1 
ATOM   4210 O O     . GLN B 1 288 ? 124.044 118.843 158.066 1.00 88.90  ? 288 GLN D O     1 
ATOM   4211 C CB    . GLN B 1 288 ? 126.395 117.462 158.550 1.00 81.35  ? 288 GLN D CB    1 
ATOM   4212 C CG    . GLN B 1 288 ? 126.481 116.125 157.821 1.00 83.53  ? 288 GLN D CG    1 
ATOM   4213 C CD    . GLN B 1 288 ? 125.224 115.786 157.046 1.00 80.90  ? 288 GLN D CD    1 
ATOM   4214 O OE1   . GLN B 1 288 ? 124.374 116.642 156.813 1.00 81.77  ? 288 GLN D OE1   1 
ATOM   4215 N NE2   . GLN B 1 288 ? 125.103 114.528 156.640 1.00 76.44  ? 288 GLN D NE2   1 
ATOM   4216 N N     . ALA B 1 289 ? 123.014 118.196 159.944 1.00 93.07  ? 289 ALA D N     1 
ATOM   4217 C CA    . ALA B 1 289 ? 121.750 118.847 159.639 1.00 96.85  ? 289 ALA D CA    1 
ATOM   4218 C C     . ALA B 1 289 ? 121.485 119.960 160.650 1.00 101.96 ? 289 ALA D C     1 
ATOM   4219 O O     . ALA B 1 289 ? 122.290 120.227 161.547 1.00 102.42 ? 289 ALA D O     1 
ATOM   4220 C CB    . ALA B 1 289 ? 120.612 117.824 159.631 1.00 95.84  ? 289 ALA D CB    1 
ATOM   4221 N N     . THR B 1 290 ? 120.338 120.619 160.490 1.00 103.07 ? 290 THR D N     1 
ATOM   4222 C CA    . THR B 1 290 ? 119.889 121.668 161.406 1.00 104.04 ? 290 THR D CA    1 
ATOM   4223 C C     . THR B 1 290 ? 120.907 122.810 161.475 1.00 101.15 ? 290 THR D C     1 
ATOM   4224 O O     . THR B 1 290 ? 121.528 123.070 162.507 1.00 99.94  ? 290 THR D O     1 
ATOM   4225 C CB    . THR B 1 290 ? 119.614 121.092 162.799 1.00 104.27 ? 290 THR D CB    1 
ATOM   4226 O OG1   . THR B 1 290 ? 118.732 119.969 162.688 1.00 103.38 ? 290 THR D OG1   1 
ATOM   4227 C CG2   . THR B 1 290 ? 118.976 122.142 163.699 1.00 99.10  ? 290 THR D CG2   1 
ATOM   4228 N N     . GLY B 1 291 ? 121.071 123.488 160.341 1.00 100.08 ? 291 GLY D N     1 
ATOM   4229 C CA    . GLY B 1 291 ? 121.949 124.640 160.259 1.00 99.53  ? 291 GLY D CA    1 
ATOM   4230 C C     . GLY B 1 291 ? 121.223 125.879 159.776 1.00 101.59 ? 291 GLY D C     1 
ATOM   4231 O O     . GLY B 1 291 ? 120.511 125.832 158.769 1.00 97.99  ? 291 GLY D O     1 
ATOM   4232 N N     . SER B 1 292 ? 121.396 126.996 160.483 1.00 101.29 ? 292 SER D N     1 
ATOM   4233 C CA    . SER B 1 292 ? 120.700 128.235 160.165 1.00 97.41  ? 292 SER D CA    1 
ATOM   4234 C C     . SER B 1 292 ? 121.679 129.397 160.270 1.00 92.36  ? 292 SER D C     1 
ATOM   4235 O O     . SER B 1 292 ? 122.835 129.234 160.672 1.00 88.58  ? 292 SER D O     1 
ATOM   4236 C CB    . SER B 1 292 ? 119.491 128.442 161.086 1.00 93.53  ? 292 SER D CB    1 
ATOM   4237 O OG    . SER B 1 292 ? 119.887 128.967 162.341 1.00 89.91  ? 292 SER D OG    1 
ATOM   4238 N N     . CYS B 1 293 ? 121.200 130.584 159.907 1.00 89.50  ? 293 CYS D N     1 
ATOM   4239 C CA    . CYS B 1 293 ? 122.011 131.791 159.871 1.00 85.79  ? 293 CYS D CA    1 
ATOM   4240 C C     . CYS B 1 293 ? 121.771 132.615 161.128 1.00 86.92  ? 293 CYS D C     1 
ATOM   4241 O O     . CYS B 1 293 ? 120.638 132.720 161.605 1.00 86.18  ? 293 CYS D O     1 
ATOM   4242 C CB    . CYS B 1 293 ? 121.680 132.622 158.629 1.00 84.95  ? 293 CYS D CB    1 
ATOM   4243 S SG    . CYS B 1 293 ? 123.049 133.616 158.003 1.00 88.89  ? 293 CYS D SG    1 
ATOM   4244 N N     . PHE B 1 294 ? 122.842 133.196 161.661 1.00 86.77  ? 294 PHE D N     1 
ATOM   4245 C CA    . PHE B 1 294 ? 122.775 133.981 162.892 1.00 84.09  ? 294 PHE D CA    1 
ATOM   4246 C C     . PHE B 1 294 ? 123.533 135.293 162.723 1.00 81.36  ? 294 PHE D C     1 
ATOM   4247 O O     . PHE B 1 294 ? 124.317 135.700 163.580 1.00 83.07  ? 294 PHE D O     1 
ATOM   4248 C CB    . PHE B 1 294 ? 123.326 133.188 164.075 1.00 85.12  ? 294 PHE D CB    1 
ATOM   4249 C CG    . PHE B 1 294 ? 122.454 132.041 164.497 1.00 93.44  ? 294 PHE D CG    1 
ATOM   4250 C CD1   . PHE B 1 294 ? 121.341 132.258 165.290 1.00 94.89  ? 294 PHE D CD1   1 
ATOM   4251 C CD2   . PHE B 1 294 ? 122.749 130.747 164.107 1.00 99.80  ? 294 PHE D CD2   1 
ATOM   4252 C CE1   . PHE B 1 294 ? 120.537 131.206 165.684 1.00 93.14  ? 294 PHE D CE1   1 
ATOM   4253 C CE2   . PHE B 1 294 ? 121.947 129.691 164.498 1.00 100.99 ? 294 PHE D CE2   1 
ATOM   4254 C CZ    . PHE B 1 294 ? 120.841 129.923 165.287 1.00 95.43  ? 294 PHE D CZ    1 
ATOM   4255 N N     . LEU B 1 295 ? 123.300 135.977 161.608 1.00 76.47  ? 295 LEU D N     1 
ATOM   4256 C CA    . LEU B 1 295 ? 123.951 137.244 161.313 1.00 67.67  ? 295 LEU D CA    1 
ATOM   4257 C C     . LEU B 1 295 ? 122.945 138.384 161.399 1.00 59.77  ? 295 LEU D C     1 
ATOM   4258 O O     . LEU B 1 295 ? 121.735 138.185 161.277 1.00 63.86  ? 295 LEU D O     1 
ATOM   4259 C CB    . LEU B 1 295 ? 124.595 137.221 159.923 1.00 68.16  ? 295 LEU D CB    1 
ATOM   4260 C CG    . LEU B 1 295 ? 125.220 135.891 159.499 1.00 74.76  ? 295 LEU D CG    1 
ATOM   4261 C CD1   . LEU B 1 295 ? 125.600 135.924 158.029 1.00 76.38  ? 295 LEU D CD1   1 
ATOM   4262 C CD2   . LEU B 1 295 ? 126.426 135.562 160.361 1.00 81.68  ? 295 LEU D CD2   1 
ATOM   4263 N N     . VAL B 1 296 ? 123.459 139.590 161.630 1.00 51.75  ? 296 VAL D N     1 
ATOM   4264 C CA    . VAL B 1 296 ? 122.631 140.789 161.650 1.00 47.39  ? 296 VAL D CA    1 
ATOM   4265 C C     . VAL B 1 296 ? 123.368 141.908 160.929 1.00 51.77  ? 296 VAL D C     1 
ATOM   4266 O O     . VAL B 1 296 ? 124.269 142.537 161.494 1.00 55.90  ? 296 VAL D O     1 
ATOM   4267 C CB    . VAL B 1 296 ? 122.274 141.201 163.087 1.00 53.22  ? 296 VAL D CB    1 
ATOM   4268 C CG1   . VAL B 1 296 ? 121.360 142.409 163.075 1.00 53.51  ? 296 VAL D CG1   1 
ATOM   4269 C CG2   . VAL B 1 296 ? 121.620 140.047 163.820 1.00 57.97  ? 296 VAL D CG2   1 
ATOM   4270 N N     . VAL B 1 297 ? 122.983 142.171 159.681 1.00 52.17  ? 297 VAL D N     1 
ATOM   4271 C CA    . VAL B 1 297 ? 123.691 143.167 158.888 1.00 47.17  ? 297 VAL D CA    1 
ATOM   4272 C C     . VAL B 1 297 ? 123.412 144.567 159.424 1.00 44.74  ? 297 VAL D C     1 
ATOM   4273 O O     . VAL B 1 297 ? 122.398 144.833 160.078 1.00 46.04  ? 297 VAL D O     1 
ATOM   4274 C CB    . VAL B 1 297 ? 123.309 143.055 157.403 1.00 45.54  ? 297 VAL D CB    1 
ATOM   4275 C CG1   . VAL B 1 297 ? 123.815 141.744 156.830 1.00 50.67  ? 297 VAL D CG1   1 
ATOM   4276 C CG2   . VAL B 1 297 ? 121.805 143.175 157.222 1.00 42.44  ? 297 VAL D CG2   1 
ATOM   4277 N N     . ALA B 1 298 ? 124.340 145.475 159.143 1.00 46.92  ? 298 ALA D N     1 
ATOM   4278 C CA    . ALA B 1 298 ? 124.185 146.858 159.562 1.00 52.82  ? 298 ALA D CA    1 
ATOM   4279 C C     . ALA B 1 298 ? 123.056 147.522 158.788 1.00 48.31  ? 298 ALA D C     1 
ATOM   4280 O O     . ALA B 1 298 ? 122.854 147.252 157.601 1.00 54.31  ? 298 ALA D O     1 
ATOM   4281 C CB    . ALA B 1 298 ? 125.488 147.625 159.348 1.00 57.17  ? 298 ALA D CB    1 
ATOM   4282 N N     . SER B 1 299 ? 122.318 148.396 159.464 1.00 45.87  ? 299 SER D N     1 
ATOM   4283 C CA    . SER B 1 299 ? 121.225 149.106 158.816 1.00 53.82  ? 299 SER D CA    1 
ATOM   4284 C C     . SER B 1 299 ? 120.726 150.207 159.737 1.00 50.85  ? 299 SER D C     1 
ATOM   4285 O O     . SER B 1 299 ? 120.726 150.056 160.961 1.00 52.55  ? 299 SER D O     1 
ATOM   4286 C CB    . SER B 1 299 ? 120.076 148.156 158.462 1.00 54.72  ? 299 SER D CB    1 
ATOM   4287 O OG    . SER B 1 299 ? 119.238 147.934 159.581 1.00 51.43  ? 299 SER D OG    1 
ATOM   4288 N N     . HIS B 1 300 ? 120.299 151.313 159.130 1.00 48.34  ? 300 HIS D N     1 
ATOM   4289 C CA    . HIS B 1 300 ? 119.690 152.420 159.862 1.00 48.97  ? 300 HIS D CA    1 
ATOM   4290 C C     . HIS B 1 300 ? 120.617 152.935 160.959 1.00 58.89  ? 300 HIS D C     1 
ATOM   4291 O O     . HIS B 1 300 ? 120.174 153.326 162.040 1.00 61.07  ? 300 HIS D O     1 
ATOM   4292 C CB    . HIS B 1 300 ? 118.340 152.006 160.447 1.00 48.66  ? 300 HIS D CB    1 
ATOM   4293 C CG    . HIS B 1 300 ? 117.448 151.307 159.468 1.00 48.24  ? 300 HIS D CG    1 
ATOM   4294 N ND1   . HIS B 1 300 ? 117.526 149.953 159.226 1.00 44.63  ? 300 HIS D ND1   1 
ATOM   4295 C CD2   . HIS B 1 300 ? 116.457 151.774 158.673 1.00 52.34  ? 300 HIS D CD2   1 
ATOM   4296 C CE1   . HIS B 1 300 ? 116.623 149.617 158.323 1.00 43.72  ? 300 HIS D CE1   1 
ATOM   4297 N NE2   . HIS B 1 300 ? 115.961 150.703 157.971 1.00 44.50  ? 300 HIS D NE2   1 
ATOM   4298 N N     . GLY B 1 301 ? 121.919 152.941 160.679 1.00 62.50  ? 301 GLY D N     1 
ATOM   4299 C CA    . GLY B 1 301 ? 122.905 153.432 161.615 1.00 59.31  ? 301 GLY D CA    1 
ATOM   4300 C C     . GLY B 1 301 ? 123.456 152.397 162.572 1.00 54.50  ? 301 GLY D C     1 
ATOM   4301 O O     . GLY B 1 301 ? 124.423 152.692 163.286 1.00 55.13  ? 301 GLY D O     1 
ATOM   4302 N N     . LEU B 1 302 ? 122.881 151.200 162.612 1.00 52.44  ? 302 LEU D N     1 
ATOM   4303 C CA    . LEU B 1 302 ? 123.407 150.140 163.453 1.00 52.57  ? 302 LEU D CA    1 
ATOM   4304 C C     . LEU B 1 302 ? 124.681 149.566 162.838 1.00 54.48  ? 302 LEU D C     1 
ATOM   4305 O O     . LEU B 1 302 ? 125.016 149.823 161.681 1.00 55.83  ? 302 LEU D O     1 
ATOM   4306 C CB    . LEU B 1 302 ? 122.363 149.042 163.646 1.00 55.42  ? 302 LEU D CB    1 
ATOM   4307 C CG    . LEU B 1 302 ? 121.065 149.473 164.329 1.00 53.01  ? 302 LEU D CG    1 
ATOM   4308 C CD1   . LEU B 1 302 ? 119.963 148.460 164.069 1.00 49.91  ? 302 LEU D CD1   1 
ATOM   4309 C CD2   . LEU B 1 302 ? 121.287 149.657 165.816 1.00 58.32  ? 302 LEU D CD2   1 
ATOM   4310 N N     . SER B 1 303 ? 125.398 148.778 163.632 1.00 57.49  ? 303 SER D N     1 
ATOM   4311 C CA    . SER B 1 303 ? 126.661 148.187 163.218 1.00 59.60  ? 303 SER D CA    1 
ATOM   4312 C C     . SER B 1 303 ? 126.488 146.691 163.006 1.00 55.57  ? 303 SER D C     1 
ATOM   4313 O O     . SER B 1 303 ? 125.756 146.029 163.747 1.00 57.54  ? 303 SER D O     1 
ATOM   4314 C CB    . SER B 1 303 ? 127.755 148.445 164.257 1.00 70.43  ? 303 SER D CB    1 
ATOM   4315 O OG    . SER B 1 303 ? 129.036 148.466 163.651 1.00 77.91  ? 303 SER D OG    1 
ATOM   4316 N N     . ALA B 1 304 ? 127.168 146.163 161.993 1.00 56.78  ? 304 ALA D N     1 
ATOM   4317 C CA    . ALA B 1 304 ? 127.022 144.760 161.643 1.00 63.39  ? 304 ALA D CA    1 
ATOM   4318 C C     . ALA B 1 304 ? 127.492 143.865 162.783 1.00 61.32  ? 304 ALA D C     1 
ATOM   4319 O O     . ALA B 1 304 ? 128.429 144.190 163.516 1.00 59.52  ? 304 ALA D O     1 
ATOM   4320 C CB    . ALA B 1 304 ? 127.811 144.441 160.374 1.00 59.04  ? 304 ALA D CB    1 
ATOM   4321 N N     . ILE B 1 305 ? 126.822 142.726 162.926 1.00 60.79  ? 305 ILE D N     1 
ATOM   4322 C CA    . ILE B 1 305 ? 127.160 141.719 163.924 1.00 63.68  ? 305 ILE D CA    1 
ATOM   4323 C C     . ILE B 1 305 ? 127.465 140.420 163.195 1.00 70.42  ? 305 ILE D C     1 
ATOM   4324 O O     . ILE B 1 305 ? 126.666 139.963 162.371 1.00 73.55  ? 305 ILE D O     1 
ATOM   4325 C CB    . ILE B 1 305 ? 126.021 141.523 164.940 1.00 64.42  ? 305 ILE D CB    1 
ATOM   4326 C CG1   . ILE B 1 305 ? 125.874 142.763 165.822 1.00 63.85  ? 305 ILE D CG1   1 
ATOM   4327 C CG2   . ILE B 1 305 ? 126.279 140.290 165.792 1.00 72.70  ? 305 ILE D CG2   1 
ATOM   4328 C CD1   . ILE B 1 305 ? 124.543 142.851 166.531 1.00 63.40  ? 305 ILE D CD1   1 
ATOM   4329 N N     . ALA B 1 306 ? 128.622 139.828 163.494 1.00 74.71  ? 306 ALA D N     1 
ATOM   4330 C CA    . ALA B 1 306 ? 128.982 138.565 162.862 1.00 76.30  ? 306 ALA D CA    1 
ATOM   4331 C C     . ALA B 1 306 ? 128.184 137.402 163.436 1.00 77.91  ? 306 ALA D C     1 
ATOM   4332 O O     . ALA B 1 306 ? 127.957 136.407 162.740 1.00 75.97  ? 306 ALA D O     1 
ATOM   4333 C CB    . ALA B 1 306 ? 130.479 138.307 163.020 1.00 80.27  ? 306 ALA D CB    1 
ATOM   4334 N N     . ASP B 1 307 ? 127.757 137.503 164.692 1.00 85.49  ? 307 ASP D N     1 
ATOM   4335 C CA    . ASP B 1 307 ? 126.989 136.433 165.324 1.00 93.81  ? 307 ASP D CA    1 
ATOM   4336 C C     . ASP B 1 307 ? 126.213 137.025 166.488 1.00 93.20  ? 307 ASP D C     1 
ATOM   4337 O O     . ASP B 1 307 ? 126.788 137.745 167.310 1.00 88.11  ? 307 ASP D O     1 
ATOM   4338 C CB    . ASP B 1 307 ? 127.906 135.307 165.803 1.00 94.85  ? 307 ASP D CB    1 
ATOM   4339 C CG    . ASP B 1 307 ? 127.173 133.990 165.973 1.00 96.13  ? 307 ASP D CG    1 
ATOM   4340 O OD1   . ASP B 1 307 ? 126.051 133.997 166.522 1.00 94.81  ? 307 ASP D OD1   1 
ATOM   4341 O OD2   . ASP B 1 307 ? 127.720 132.946 165.559 1.00 96.69  ? 307 ASP D OD2   1 
ATOM   4342 N N     . SER B 1 308 ? 124.914 136.732 166.556 1.00 93.77  ? 308 SER D N     1 
ATOM   4343 C CA    . SER B 1 308 ? 124.105 137.229 167.663 1.00 91.81  ? 308 SER D CA    1 
ATOM   4344 C C     . SER B 1 308 ? 124.417 136.484 168.954 1.00 98.10  ? 308 SER D C     1 
ATOM   4345 O O     . SER B 1 308 ? 124.500 137.096 170.025 1.00 98.62  ? 308 SER D O     1 
ATOM   4346 C CB    . SER B 1 308 ? 122.622 137.106 167.323 1.00 89.19  ? 308 SER D CB    1 
ATOM   4347 O OG    . SER B 1 308 ? 122.088 135.895 167.828 1.00 94.37  ? 308 SER D OG    1 
ATOM   4348 N N     . ARG B 1 309 ? 124.587 135.162 168.876 1.00 100.42 ? 309 ARG D N     1 
ATOM   4349 C CA    . ARG B 1 309 ? 124.838 134.376 170.081 1.00 102.24 ? 309 ARG D CA    1 
ATOM   4350 C C     . ARG B 1 309 ? 126.143 134.793 170.745 1.00 100.57 ? 309 ARG D C     1 
ATOM   4351 O O     . ARG B 1 309 ? 126.177 135.103 171.942 1.00 93.98  ? 309 ARG D O     1 
ATOM   4352 C CB    . ARG B 1 309 ? 124.878 132.887 169.738 1.00 103.88 ? 309 ARG D CB    1 
ATOM   4353 C CG    . ARG B 1 309 ? 123.557 132.313 169.264 1.00 101.34 ? 309 ARG D CG    1 
ATOM   4354 C CD    . ARG B 1 309 ? 123.561 132.058 167.766 1.00 99.48  ? 309 ARG D CD    1 
ATOM   4355 N NE    . ARG B 1 309 ? 124.635 131.162 167.354 1.00 100.78 ? 309 ARG D NE    1 
ATOM   4356 C CZ    . ARG B 1 309 ? 124.596 129.841 167.466 1.00 100.81 ? 309 ARG D CZ    1 
ATOM   4357 N NH1   . ARG B 1 309 ? 123.550 129.220 167.985 1.00 99.25  ? 309 ARG D NH1   1 
ATOM   4358 N NH2   . ARG B 1 309 ? 125.635 129.124 167.046 1.00 104.76 ? 309 ARG D NH2   1 
ATOM   4359 N N     . ILE B 1 310 ? 127.234 134.810 169.976 1.00 100.38 ? 310 ILE D N     1 
ATOM   4360 C CA    . ILE B 1 310 ? 128.540 135.107 170.545 1.00 101.71 ? 310 ILE D CA    1 
ATOM   4361 C C     . ILE B 1 310 ? 128.608 136.532 171.066 1.00 101.61 ? 310 ILE D C     1 
ATOM   4362 O O     . ILE B 1 310 ? 129.424 136.826 171.947 1.00 105.27 ? 310 ILE D O     1 
ATOM   4363 C CB    . ILE B 1 310 ? 129.640 134.847 169.498 1.00 105.71 ? 310 ILE D CB    1 
ATOM   4364 C CG1   . ILE B 1 310 ? 129.861 133.342 169.333 1.00 107.22 ? 310 ILE D CG1   1 
ATOM   4365 C CG2   . ILE B 1 310 ? 130.942 135.523 169.904 1.00 109.45 ? 310 ILE D CG2   1 
ATOM   4366 C CD1   . ILE B 1 310 ? 130.555 132.961 168.044 1.00 104.39 ? 310 ILE D CD1   1 
ATOM   4367 N N     . GLU B 1 311 ? 127.770 137.429 170.548 1.00 101.97 ? 311 GLU D N     1 
ATOM   4368 C CA    . GLU B 1 311 ? 127.791 138.813 171.004 1.00 104.20 ? 311 GLU D CA    1 
ATOM   4369 C C     . GLU B 1 311 ? 127.581 138.887 172.511 1.00 103.10 ? 311 GLU D C     1 
ATOM   4370 O O     . GLU B 1 311 ? 128.466 139.324 173.255 1.00 102.51 ? 311 GLU D O     1 
ATOM   4371 C CB    . GLU B 1 311 ? 126.720 139.620 170.269 1.00 104.29 ? 311 GLU D CB    1 
ATOM   4372 C CG    . GLU B 1 311 ? 126.916 141.122 170.355 1.00 99.17  ? 311 GLU D CG    1 
ATOM   4373 C CD    . GLU B 1 311 ? 128.126 141.594 169.574 1.00 93.38  ? 311 GLU D CD    1 
ATOM   4374 O OE1   . GLU B 1 311 ? 128.678 140.796 168.789 1.00 91.32  ? 311 GLU D OE1   1 
ATOM   4375 O OE2   . GLU B 1 311 ? 128.523 142.764 169.745 1.00 88.72  ? 311 GLU D OE2   1 
ATOM   4376 N N     . GLY B 1 312 ? 126.411 138.453 172.978 1.00 101.98 ? 312 GLY D N     1 
ATOM   4377 C CA    . GLY B 1 312 ? 126.118 138.432 174.397 1.00 105.17 ? 312 GLY D CA    1 
ATOM   4378 C C     . GLY B 1 312 ? 126.522 139.718 175.081 1.00 110.50 ? 312 GLY D C     1 
ATOM   4379 O O     . GLY B 1 312 ? 125.962 140.783 174.807 1.00 113.91 ? 312 GLY D O     1 
ATOM   4380 N N     . THR B 1 313 ? 127.503 139.628 175.977 1.00 115.46 ? 313 THR D N     1 
ATOM   4381 C CA    . THR B 1 313 ? 128.090 140.792 176.626 1.00 117.01 ? 313 THR D CA    1 
ATOM   4382 C C     . THR B 1 313 ? 129.608 140.797 176.464 1.00 115.54 ? 313 THR D C     1 
ATOM   4383 O O     . THR B 1 313 ? 130.336 141.232 177.359 1.00 114.98 ? 313 THR D O     1 
ATOM   4384 C CB    . THR B 1 313 ? 127.709 140.840 178.105 1.00 115.14 ? 313 THR D CB    1 
ATOM   4385 O OG1   . THR B 1 313 ? 126.375 140.345 178.274 1.00 109.16 ? 313 THR D OG1   1 
ATOM   4386 C CG2   . THR B 1 313 ? 127.788 142.267 178.628 1.00 108.28 ? 313 THR D CG2   1 
ATOM   4387 N N     . GLY B 1 314 ? 130.096 140.313 175.321 1.00 111.71 ? 314 GLY D N     1 
ATOM   4388 C CA    . GLY B 1 314 ? 131.510 140.279 175.016 1.00 113.11 ? 314 GLY D CA    1 
ATOM   4389 C C     . GLY B 1 314 ? 132.165 138.932 175.234 1.00 117.77 ? 314 GLY D C     1 
ATOM   4390 O O     . GLY B 1 314 ? 133.365 138.793 174.967 1.00 117.49 ? 314 GLY D O     1 
ATOM   4391 N N     . ASN B 1 315 ? 131.419 137.939 175.709 1.00 119.42 ? 315 ASN D N     1 
ATOM   4392 C CA    . ASN B 1 315 ? 131.980 136.623 176.007 1.00 119.58 ? 315 ASN D CA    1 
ATOM   4393 C C     . ASN B 1 315 ? 132.127 135.837 174.711 1.00 117.32 ? 315 ASN D C     1 
ATOM   4394 O O     . ASN B 1 315 ? 131.159 135.275 174.195 1.00 113.69 ? 315 ASN D O     1 
ATOM   4395 C CB    . ASN B 1 315 ? 131.093 135.884 177.004 1.00 116.05 ? 315 ASN D CB    1 
ATOM   4396 C CG    . ASN B 1 315 ? 130.596 136.783 178.120 1.00 114.67 ? 315 ASN D CG    1 
ATOM   4397 O OD1   . ASN B 1 315 ? 131.104 137.887 178.316 1.00 116.50 ? 315 ASN D OD1   1 
ATOM   4398 N ND2   . ASN B 1 315 ? 129.603 136.310 178.863 1.00 115.01 ? 315 ASN D ND2   1 
ATOM   4399 N N     . THR B 1 316 ? 133.344 135.798 174.176 1.00 117.74 ? 316 THR D N     1 
ATOM   4400 C CA    . THR B 1 316 ? 133.635 135.070 172.939 1.00 116.97 ? 316 THR D CA    1 
ATOM   4401 C C     . THR B 1 316 ? 134.205 133.687 173.249 1.00 118.86 ? 316 THR D C     1 
ATOM   4402 O O     . THR B 1 316 ? 135.306 133.325 172.835 1.00 117.14 ? 316 THR D O     1 
ATOM   4403 C CB    . THR B 1 316 ? 134.587 135.880 172.059 1.00 120.79 ? 316 THR D CB    1 
ATOM   4404 O OG1   . THR B 1 316 ? 134.769 135.209 170.805 1.00 119.38 ? 316 THR D OG1   1 
ATOM   4405 C CG2   . THR B 1 316 ? 135.946 136.057 172.733 1.00 119.79 ? 316 THR D CG2   1 
ATOM   4406 N N     . ASN B 1 317 ? 133.427 132.904 173.991 1.00 119.51 ? 317 ASN D N     1 
ATOM   4407 C CA    . ASN B 1 317 ? 133.805 131.551 174.395 1.00 115.91 ? 317 ASN D CA    1 
ATOM   4408 C C     . ASN B 1 317 ? 132.989 130.568 173.555 1.00 112.20 ? 317 ASN D C     1 
ATOM   4409 O O     . ASN B 1 317 ? 131.967 130.041 174.001 1.00 107.64 ? 317 ASN D O     1 
ATOM   4410 C CB    . ASN B 1 317 ? 133.574 131.348 175.894 1.00 113.85 ? 317 ASN D CB    1 
ATOM   4411 C CG    . ASN B 1 317 ? 134.652 130.503 176.545 1.00 113.34 ? 317 ASN D CG    1 
ATOM   4412 O OD1   . ASN B 1 317 ? 135.746 130.340 176.005 1.00 108.35 ? 317 ASN D OD1   1 
ATOM   4413 N ND2   . ASN B 1 317 ? 134.344 129.958 177.717 1.00 119.99 ? 317 ASN D ND2   1 
ATOM   4414 N N     . LEU B 1 318 ? 133.454 130.321 172.334 1.00 112.80 ? 318 LEU D N     1 
ATOM   4415 C CA    . LEU B 1 318 ? 132.776 129.414 171.408 1.00 108.07 ? 318 LEU D CA    1 
ATOM   4416 C C     . LEU B 1 318 ? 133.388 128.016 171.479 1.00 106.67 ? 318 LEU D C     1 
ATOM   4417 O O     . LEU B 1 318 ? 133.983 127.511 170.526 1.00 106.74 ? 318 LEU D O     1 
ATOM   4418 C CB    . LEU B 1 318 ? 132.832 129.974 169.990 1.00 105.09 ? 318 LEU D CB    1 
ATOM   4419 C CG    . LEU B 1 318 ? 132.056 129.206 168.917 1.00 104.54 ? 318 LEU D CG    1 
ATOM   4420 C CD1   . LEU B 1 318 ? 130.569 129.129 169.246 1.00 105.23 ? 318 LEU D CD1   1 
ATOM   4421 C CD2   . LEU B 1 318 ? 132.274 129.847 167.558 1.00 101.48 ? 318 LEU D CD2   1 
ATOM   4422 N N     . LEU B 1 319 ? 133.237 127.390 172.645 1.00 105.96 ? 319 LEU D N     1 
ATOM   4423 C CA    . LEU B 1 319 ? 133.659 126.014 172.856 1.00 104.66 ? 319 LEU D CA    1 
ATOM   4424 C C     . LEU B 1 319 ? 132.534 125.132 173.377 1.00 107.82 ? 319 LEU D C     1 
ATOM   4425 O O     . LEU B 1 319 ? 132.749 123.930 173.572 1.00 103.87 ? 319 LEU D O     1 
ATOM   4426 C CB    . LEU B 1 319 ? 134.842 125.960 173.832 1.00 105.81 ? 319 LEU D CB    1 
ATOM   4427 C CG    . LEU B 1 319 ? 136.135 126.643 173.376 1.00 101.65 ? 319 LEU D CG    1 
ATOM   4428 C CD1   . LEU B 1 319 ? 137.159 126.630 174.499 1.00 102.64 ? 319 LEU D CD1   1 
ATOM   4429 C CD2   . LEU B 1 319 ? 136.698 125.983 172.130 1.00 98.02  ? 319 LEU D CD2   1 
ATOM   4430 N N     . GLU B 1 320 ? 131.346 125.690 173.610 1.00 113.91 ? 320 GLU D N     1 
ATOM   4431 C CA    . GLU B 1 320 ? 130.213 124.916 174.097 1.00 113.40 ? 320 GLU D CA    1 
ATOM   4432 C C     . GLU B 1 320 ? 129.471 124.193 172.983 1.00 106.51 ? 320 GLU D C     1 
ATOM   4433 O O     . GLU B 1 320 ? 128.589 123.379 173.276 1.00 101.59 ? 320 GLU D O     1 
ATOM   4434 C CB    . GLU B 1 320 ? 129.237 125.830 174.844 1.00 114.92 ? 320 GLU D CB    1 
ATOM   4435 C CG    . GLU B 1 320 ? 129.866 126.626 175.980 1.00 111.46 ? 320 GLU D CG    1 
ATOM   4436 C CD    . GLU B 1 320 ? 129.030 127.824 176.390 1.00 114.23 ? 320 GLU D CD    1 
ATOM   4437 O OE1   . GLU B 1 320 ? 128.058 128.150 175.677 1.00 110.56 ? 320 GLU D OE1   1 
ATOM   4438 O OE2   . GLU B 1 320 ? 129.347 128.441 177.429 1.00 121.06 ? 320 GLU D OE2   1 
ATOM   4439 N N     . GLU B 1 321 ? 129.799 124.470 171.724 1.00 107.52 ? 321 GLU D N     1 
ATOM   4440 C CA    . GLU B 1 321 ? 129.117 123.820 170.616 1.00 108.32 ? 321 GLU D CA    1 
ATOM   4441 C C     . GLU B 1 321 ? 129.358 122.316 170.655 1.00 102.96 ? 321 GLU D C     1 
ATOM   4442 O O     . GLU B 1 321 ? 130.437 121.845 171.027 1.00 102.03 ? 321 GLU D O     1 
ATOM   4443 C CB    . GLU B 1 321 ? 129.599 124.397 169.285 1.00 105.74 ? 321 GLU D CB    1 
ATOM   4444 C CG    . GLU B 1 321 ? 129.188 125.842 169.049 1.00 102.87 ? 321 GLU D CG    1 
ATOM   4445 C CD    . GLU B 1 321 ? 127.754 125.973 168.577 1.00 105.27 ? 321 GLU D CD    1 
ATOM   4446 O OE1   . GLU B 1 321 ? 126.856 125.403 169.231 1.00 109.53 ? 321 GLU D OE1   1 
ATOM   4447 O OE2   . GLU B 1 321 ? 127.524 126.648 167.552 1.00 101.85 ? 321 GLU D OE2   1 
ATOM   4448 N N     . CYS B 1 322 ? 128.338 121.559 170.264 1.00 97.01  ? 322 CYS D N     1 
ATOM   4449 C CA    . CYS B 1 322 ? 128.384 120.107 170.316 1.00 96.17  ? 322 CYS D CA    1 
ATOM   4450 C C     . CYS B 1 322 ? 128.021 119.521 168.960 1.00 98.79  ? 322 CYS D C     1 
ATOM   4451 O O     . CYS B 1 322 ? 127.271 120.118 168.183 1.00 97.68  ? 322 CYS D O     1 
ATOM   4452 C CB    . CYS B 1 322 ? 127.431 119.554 171.383 1.00 99.56  ? 322 CYS D CB    1 
ATOM   4453 S SG    . CYS B 1 322 ? 128.069 119.639 173.070 1.00 105.68 ? 322 CYS D SG    1 
ATOM   4454 N N     . ILE B 1 323 ? 128.566 118.338 168.692 1.00 97.52  ? 323 ILE D N     1 
ATOM   4455 C CA    . ILE B 1 323 ? 128.268 117.570 167.489 1.00 91.82  ? 323 ILE D CA    1 
ATOM   4456 C C     . ILE B 1 323 ? 127.381 116.399 167.883 1.00 89.68  ? 323 ILE D C     1 
ATOM   4457 O O     . ILE B 1 323 ? 127.622 115.741 168.902 1.00 89.41  ? 323 ILE D O     1 
ATOM   4458 C CB    . ILE B 1 323 ? 129.547 117.074 166.786 1.00 84.75  ? 323 ILE D CB    1 
ATOM   4459 C CG1   . ILE B 1 323 ? 130.490 116.400 167.785 1.00 83.06  ? 323 ILE D CG1   1 
ATOM   4460 C CG2   . ILE B 1 323 ? 130.251 118.226 166.092 1.00 82.14  ? 323 ILE D CG2   1 
ATOM   4461 C CD1   . ILE B 1 323 ? 131.149 115.156 167.244 1.00 81.64  ? 323 ILE D CD1   1 
ATOM   4462 N N     . ALA B 1 324 ? 126.348 116.151 167.082 1.00 85.54  ? 324 ALA D N     1 
ATOM   4463 C CA    . ALA B 1 324 ? 125.389 115.090 167.356 1.00 85.33  ? 324 ALA D CA    1 
ATOM   4464 C C     . ALA B 1 324 ? 125.904 113.784 166.765 1.00 82.07  ? 324 ALA D C     1 
ATOM   4465 O O     . ALA B 1 324 ? 126.147 113.697 165.558 1.00 81.01  ? 324 ALA D O     1 
ATOM   4466 C CB    . ALA B 1 324 ? 124.018 115.440 166.780 1.00 86.13  ? 324 ALA D CB    1 
ATOM   4467 N N     . ILE B 1 325 ? 126.063 112.775 167.615 1.00 86.82  ? 325 ILE D N     1 
ATOM   4468 C CA    . ILE B 1 325 ? 126.561 111.464 167.216 1.00 84.82  ? 325 ILE D CA    1 
ATOM   4469 C C     . ILE B 1 325 ? 125.451 110.450 167.454 1.00 91.09  ? 325 ILE D C     1 
ATOM   4470 O O     . ILE B 1 325 ? 124.933 110.335 168.572 1.00 96.51  ? 325 ILE D O     1 
ATOM   4471 C CB    . ILE B 1 325 ? 127.833 111.084 167.989 1.00 85.43  ? 325 ILE D CB    1 
ATOM   4472 C CG1   . ILE B 1 325 ? 128.996 111.984 167.567 1.00 81.42  ? 325 ILE D CG1   1 
ATOM   4473 C CG2   . ILE B 1 325 ? 128.179 109.622 167.756 1.00 85.72  ? 325 ILE D CG2   1 
ATOM   4474 C CD1   . ILE B 1 325 ? 130.210 111.876 168.462 1.00 77.72  ? 325 ILE D CD1   1 
ATOM   4475 N N     . GLN B 1 326 ? 125.090 109.713 166.408 1.00 91.91  ? 326 GLN D N     1 
ATOM   4476 C CA    . GLN B 1 326 ? 124.050 108.689 166.493 1.00 97.82  ? 326 GLN D CA    1 
ATOM   4477 C C     . GLN B 1 326 ? 124.716 107.367 166.851 1.00 96.71  ? 326 GLN D C     1 
ATOM   4478 O O     . GLN B 1 326 ? 125.348 106.727 166.007 1.00 90.38  ? 326 GLN D O     1 
ATOM   4479 C CB    . GLN B 1 326 ? 123.284 108.592 165.178 1.00 98.77  ? 326 GLN D CB    1 
ATOM   4480 C CG    . GLN B 1 326 ? 122.167 107.557 165.173 1.00 100.78 ? 326 GLN D CG    1 
ATOM   4481 C CD    . GLN B 1 326 ? 120.796 108.171 165.367 1.00 100.97 ? 326 GLN D CD    1 
ATOM   4482 O OE1   . GLN B 1 326 ? 120.477 109.205 164.782 1.00 101.69 ? 326 GLN D OE1   1 
ATOM   4483 N NE2   . GLN B 1 326 ? 119.974 107.533 166.193 1.00 102.62 ? 326 GLN D NE2   1 
ATOM   4484 N N     . LYS B 1 327 ? 124.573 106.953 168.106 1.00 98.52  ? 327 LYS D N     1 
ATOM   4485 C CA    . LYS B 1 327 ? 125.125 105.693 168.581 1.00 100.93 ? 327 LYS D CA    1 
ATOM   4486 C C     . LYS B 1 327 ? 124.047 104.615 168.598 1.00 105.56 ? 327 LYS D C     1 
ATOM   4487 O O     . LYS B 1 327 ? 122.863 104.875 168.372 1.00 106.60 ? 327 LYS D O     1 
ATOM   4488 C CB    . LYS B 1 327 ? 125.733 105.860 169.977 1.00 97.93  ? 327 LYS D CB    1 
ATOM   4489 C CG    . LYS B 1 327 ? 127.029 106.649 169.995 1.00 95.28  ? 327 LYS D CG    1 
ATOM   4490 C CD    . LYS B 1 327 ? 127.714 106.562 171.348 1.00 94.90  ? 327 LYS D CD    1 
ATOM   4491 C CE    . LYS B 1 327 ? 129.011 107.352 171.363 1.00 96.35  ? 327 LYS D CE    1 
ATOM   4492 N NZ    . LYS B 1 327 ? 129.591 107.455 172.729 1.00 93.44  ? 327 LYS D NZ    1 
ATOM   4493 N N     . GLN B 1 328 ? 124.478 103.382 168.874 1.00 107.85 ? 328 GLN D N     1 
ATOM   4494 C CA    . GLN B 1 328 ? 123.539 102.266 168.902 1.00 112.28 ? 328 GLN D CA    1 
ATOM   4495 C C     . GLN B 1 328 ? 122.467 102.479 169.962 1.00 112.04 ? 328 GLN D C     1 
ATOM   4496 O O     . GLN B 1 328 ? 121.279 102.249 169.710 1.00 111.98 ? 328 GLN D O     1 
ATOM   4497 C CB    . GLN B 1 328 ? 124.288 100.957 169.155 1.00 112.38 ? 328 GLN D CB    1 
ATOM   4498 C CG    . GLN B 1 328 ? 123.534 99.713  168.709 1.00 115.52 ? 328 GLN D CG    1 
ATOM   4499 C CD    . GLN B 1 328 ? 123.373 99.631  167.202 1.00 114.44 ? 328 GLN D CD    1 
ATOM   4500 O OE1   . GLN B 1 328 ? 122.495 100.271 166.624 1.00 112.88 ? 328 GLN D OE1   1 
ATOM   4501 N NE2   . GLN B 1 328 ? 124.215 98.830  166.560 1.00 113.24 ? 328 GLN D NE2   1 
ATOM   4502 N N     . ASP B 1 329 ? 122.868 102.916 171.158 1.00 111.65 ? 329 ASP D N     1 
ATOM   4503 C CA    . ASP B 1 329 ? 121.891 103.191 172.206 1.00 115.43 ? 329 ASP D CA    1 
ATOM   4504 C C     . ASP B 1 329 ? 120.977 104.346 171.817 1.00 114.95 ? 329 ASP D C     1 
ATOM   4505 O O     . ASP B 1 329 ? 119.759 104.280 172.018 1.00 113.01 ? 329 ASP D O     1 
ATOM   4506 C CB    . ASP B 1 329 ? 122.607 103.496 173.521 1.00 117.43 ? 329 ASP D CB    1 
ATOM   4507 C CG    . ASP B 1 329 ? 123.305 102.282 174.099 1.00 120.04 ? 329 ASP D CG    1 
ATOM   4508 O OD1   . ASP B 1 329 ? 123.034 101.158 173.628 1.00 120.49 ? 329 ASP D OD1   1 
ATOM   4509 O OD2   . ASP B 1 329 ? 124.122 102.451 175.028 1.00 120.58 ? 329 ASP D OD2   1 
ATOM   4510 N N     . GLY B 1 330 ? 121.544 105.408 171.256 1.00 114.12 ? 330 GLY D N     1 
ATOM   4511 C CA    . GLY B 1 330 ? 120.751 106.556 170.873 1.00 109.87 ? 330 GLY D CA    1 
ATOM   4512 C C     . GLY B 1 330 ? 121.641 107.712 170.463 1.00 104.65 ? 330 GLY D C     1 
ATOM   4513 O O     . GLY B 1 330 ? 122.861 107.574 170.349 1.00 106.09 ? 330 GLY D O     1 
ATOM   4514 N N     . VAL B 1 331 ? 120.999 108.855 170.245 1.00 99.78  ? 331 VAL D N     1 
ATOM   4515 C CA    . VAL B 1 331 ? 121.701 110.067 169.836 1.00 100.58 ? 331 VAL D CA    1 
ATOM   4516 C C     . VAL B 1 331 ? 122.273 110.753 171.068 1.00 100.13 ? 331 VAL D C     1 
ATOM   4517 O O     . VAL B 1 331 ? 121.583 110.912 172.082 1.00 101.65 ? 331 VAL D O     1 
ATOM   4518 C CB    . VAL B 1 331 ? 120.758 111.008 169.069 1.00 98.58  ? 331 VAL D CB    1 
ATOM   4519 C CG1   . VAL B 1 331 ? 121.421 112.359 168.844 1.00 96.02  ? 331 VAL D CG1   1 
ATOM   4520 C CG2   . VAL B 1 331 ? 120.347 110.384 167.747 1.00 98.91  ? 331 VAL D CG2   1 
ATOM   4521 N N     . ILE B 1 332 ? 123.539 111.160 170.985 1.00 97.57  ? 332 ILE D N     1 
ATOM   4522 C CA    . ILE B 1 332 ? 124.196 111.913 172.042 1.00 95.25  ? 332 ILE D CA    1 
ATOM   4523 C C     . ILE B 1 332 ? 124.835 113.150 171.424 1.00 91.69  ? 332 ILE D C     1 
ATOM   4524 O O     . ILE B 1 332 ? 124.882 113.311 170.205 1.00 93.11  ? 332 ILE D O     1 
ATOM   4525 C CB    . ILE B 1 332 ? 125.247 111.072 172.798 1.00 94.06  ? 332 ILE D CB    1 
ATOM   4526 C CG1   . ILE B 1 332 ? 126.527 110.915 171.969 1.00 92.42  ? 332 ILE D CG1   1 
ATOM   4527 C CG2   . ILE B 1 332 ? 124.674 109.708 173.146 1.00 95.01  ? 332 ILE D CG2   1 
ATOM   4528 C CD1   . ILE B 1 332 ? 127.587 110.072 172.643 1.00 91.06  ? 332 ILE D CD1   1 
ATOM   4529 N N     . LYS B 1 333 ? 125.327 114.030 172.289 1.00 90.50  ? 333 LYS D N     1 
ATOM   4530 C CA    . LYS B 1 333 ? 126.009 115.249 171.879 1.00 92.70  ? 333 LYS D CA    1 
ATOM   4531 C C     . LYS B 1 333 ? 127.390 115.277 172.515 1.00 95.87  ? 333 LYS D C     1 
ATOM   4532 O O     . LYS B 1 333 ? 127.524 115.046 173.721 1.00 99.24  ? 333 LYS D O     1 
ATOM   4533 C CB    . LYS B 1 333 ? 125.209 116.488 172.283 1.00 96.95  ? 333 LYS D CB    1 
ATOM   4534 C CG    . LYS B 1 333 ? 123.870 116.613 171.576 1.00 97.72  ? 333 LYS D CG    1 
ATOM   4535 C CD    . LYS B 1 333 ? 123.097 117.827 172.063 1.00 99.37  ? 333 LYS D CD    1 
ATOM   4536 C CE    . LYS B 1 333 ? 121.750 117.943 171.369 1.00 103.51 ? 333 LYS D CE    1 
ATOM   4537 N NZ    . LYS B 1 333 ? 120.960 119.103 171.869 1.00 106.14 ? 333 LYS D NZ    1 
ATOM   4538 N N     . CYS B 1 334 ? 128.410 115.557 171.707 1.00 97.11  ? 334 CYS D N     1 
ATOM   4539 C CA    . CYS B 1 334 ? 129.792 115.599 172.166 1.00 97.63  ? 334 CYS D CA    1 
ATOM   4540 C C     . CYS B 1 334 ? 130.331 117.016 172.038 1.00 95.97  ? 334 CYS D C     1 
ATOM   4541 O O     . CYS B 1 334 ? 130.196 117.641 170.981 1.00 93.74  ? 334 CYS D O     1 
ATOM   4542 C CB    . CYS B 1 334 ? 130.664 114.630 171.366 1.00 94.34  ? 334 CYS D CB    1 
ATOM   4543 S SG    . CYS B 1 334 ? 132.064 113.965 172.291 1.00 100.76 ? 334 CYS D SG    1 
ATOM   4544 N N     . LYS B 1 335 ? 130.944 117.514 173.110 1.00 97.99  ? 335 LYS D N     1 
ATOM   4545 C CA    . LYS B 1 335 ? 131.490 118.863 173.103 1.00 99.01  ? 335 LYS D CA    1 
ATOM   4546 C C     . LYS B 1 335 ? 132.690 118.952 172.169 1.00 92.50  ? 335 LYS D C     1 
ATOM   4547 O O     . LYS B 1 335 ? 133.575 118.093 172.185 1.00 90.67  ? 335 LYS D O     1 
ATOM   4548 C CB    . LYS B 1 335 ? 131.899 119.280 174.516 1.00 101.35 ? 335 LYS D CB    1 
ATOM   4549 C CG    . LYS B 1 335 ? 130.729 119.491 175.465 1.00 102.02 ? 335 LYS D CG    1 
ATOM   4550 C CD    . LYS B 1 335 ? 131.204 119.897 176.852 1.00 103.45 ? 335 LYS D CD    1 
ATOM   4551 C CE    . LYS B 1 335 ? 130.036 120.134 177.796 1.00 104.78 ? 335 LYS D CE    1 
ATOM   4552 N NZ    . LYS B 1 335 ? 130.492 120.454 179.176 1.00 97.37  ? 335 LYS D NZ    1 
ATOM   4553 N N     . ARG B 1 336 ? 132.721 120.009 171.364 1.00 92.55  ? 336 ARG D N     1 
ATOM   4554 C CA    . ARG B 1 336 ? 133.792 120.178 170.392 1.00 90.67  ? 336 ARG D CA    1 
ATOM   4555 C C     . ARG B 1 336 ? 135.121 120.431 171.092 1.00 87.24  ? 336 ARG D C     1 
ATOM   4556 O O     . ARG B 1 336 ? 135.188 121.136 172.102 1.00 87.91  ? 336 ARG D O     1 
ATOM   4557 C CB    . ARG B 1 336 ? 133.469 121.334 169.443 1.00 92.44  ? 336 ARG D CB    1 
ATOM   4558 C CG    . ARG B 1 336 ? 134.169 122.648 169.772 1.00 91.25  ? 336 ARG D CG    1 
ATOM   4559 C CD    . ARG B 1 336 ? 133.763 123.742 168.805 1.00 90.96  ? 336 ARG D CD    1 
ATOM   4560 N NE    . ARG B 1 336 ? 134.266 123.483 167.461 1.00 92.92  ? 336 ARG D NE    1 
ATOM   4561 C CZ    . ARG B 1 336 ? 134.030 124.256 166.411 1.00 93.88  ? 336 ARG D CZ    1 
ATOM   4562 N NH1   . ARG B 1 336 ? 133.324 125.370 166.515 1.00 96.77  ? 336 ARG D NH1   1 
ATOM   4563 N NH2   . ARG B 1 336 ? 134.520 123.905 165.225 1.00 89.73  ? 336 ARG D NH2   1 
ATOM   4564 N N     . SER B 1 337 ? 136.188 119.849 170.543 1.00 83.13  ? 337 SER D N     1 
ATOM   4565 C CA    . SER B 1 337 ? 137.525 120.069 171.074 1.00 81.95  ? 337 SER D CA    1 
ATOM   4566 C C     . SER B 1 337 ? 138.184 121.314 170.499 1.00 79.67  ? 337 SER D C     1 
ATOM   4567 O O     . SER B 1 337 ? 139.061 121.890 171.152 1.00 81.18  ? 337 SER D O     1 
ATOM   4568 C CB    . SER B 1 337 ? 138.409 118.853 170.798 1.00 84.29  ? 337 SER D CB    1 
ATOM   4569 O OG    . SER B 1 337 ? 139.780 119.180 170.944 1.00 82.92  ? 337 SER D OG    1 
ATOM   4570 N N     . GLY B 1 338 ? 137.789 121.739 169.302 1.00 81.20  ? 338 GLY D N     1 
ATOM   4571 C CA    . GLY B 1 338 ? 138.340 122.949 168.724 1.00 83.04  ? 338 GLY D CA    1 
ATOM   4572 C C     . GLY B 1 338 ? 139.771 122.835 168.242 1.00 83.97  ? 338 GLY D C     1 
ATOM   4573 O O     . GLY B 1 338 ? 140.500 123.831 168.257 1.00 86.02  ? 338 GLY D O     1 
ATOM   4574 N N     . LYS B 1 339 ? 140.198 121.645 167.822 1.00 81.72  ? 339 LYS D N     1 
ATOM   4575 C CA    . LYS B 1 339 ? 141.529 121.446 167.265 1.00 80.51  ? 339 LYS D CA    1 
ATOM   4576 C C     . LYS B 1 339 ? 141.437 120.600 166.003 1.00 78.96  ? 339 LYS D C     1 
ATOM   4577 O O     . LYS B 1 339 ? 140.557 119.746 165.868 1.00 79.56  ? 339 LYS D O     1 
ATOM   4578 C CB    . LYS B 1 339 ? 142.469 120.782 168.277 1.00 80.82  ? 339 LYS D CB    1 
ATOM   4579 C CG    . LYS B 1 339 ? 142.888 121.700 169.412 1.00 80.23  ? 339 LYS D CG    1 
ATOM   4580 C CD    . LYS B 1 339 ? 143.800 120.993 170.400 1.00 78.78  ? 339 LYS D CD    1 
ATOM   4581 C CE    . LYS B 1 339 ? 144.184 121.912 171.549 1.00 82.39  ? 339 LYS D CE    1 
ATOM   4582 N NZ    . LYS B 1 339 ? 145.001 121.219 172.583 1.00 84.26  ? 339 LYS D NZ    1 
ATOM   4583 N N     . SER B 1 340 ? 142.362 120.846 165.080 1.00 79.19  ? 340 SER D N     1 
ATOM   4584 C CA    . SER B 1 340 ? 142.345 120.168 163.793 1.00 74.29  ? 340 SER D CA    1 
ATOM   4585 C C     . SER B 1 340 ? 142.637 118.680 163.950 1.00 77.55  ? 340 SER D C     1 
ATOM   4586 O O     . SER B 1 340 ? 143.391 118.259 164.831 1.00 75.57  ? 340 SER D O     1 
ATOM   4587 C CB    . SER B 1 340 ? 143.368 120.797 162.849 1.00 73.45  ? 340 SER D CB    1 
ATOM   4588 O OG    . SER B 1 340 ? 144.687 120.577 163.314 1.00 78.53  ? 340 SER D OG    1 
ATOM   4589 N N     . LEU B 1 341 ? 142.025 117.881 163.073 1.00 74.54  ? 341 LEU D N     1 
ATOM   4590 C CA    . LEU B 1 341 ? 142.242 116.437 163.100 1.00 65.41  ? 341 LEU D CA    1 
ATOM   4591 C C     . LEU B 1 341 ? 143.686 116.089 162.768 1.00 63.18  ? 341 LEU D C     1 
ATOM   4592 O O     . LEU B 1 341 ? 144.270 115.184 163.375 1.00 69.56  ? 341 LEU D O     1 
ATOM   4593 C CB    . LEU B 1 341 ? 141.291 115.749 162.124 1.00 58.46  ? 341 LEU D CB    1 
ATOM   4594 C CG    . LEU B 1 341 ? 140.121 115.019 162.778 1.00 58.97  ? 341 LEU D CG    1 
ATOM   4595 C CD1   . LEU B 1 341 ? 139.094 114.606 161.741 1.00 57.17  ? 341 LEU D CD1   1 
ATOM   4596 C CD2   . LEU B 1 341 ? 140.617 113.813 163.555 1.00 63.31  ? 341 LEU D CD2   1 
ATOM   4597 N N     . TYR B 1 342 ? 144.277 116.789 161.801 1.00 65.60  ? 342 TYR D N     1 
ATOM   4598 C CA    . TYR B 1 342 ? 145.666 116.523 161.449 1.00 71.39  ? 342 TYR D CA    1 
ATOM   4599 C C     . TYR B 1 342 ? 146.586 116.764 162.637 1.00 78.56  ? 342 TYR D C     1 
ATOM   4600 O O     . TYR B 1 342 ? 147.510 115.981 162.885 1.00 82.82  ? 342 TYR D O     1 
ATOM   4601 C CB    . TYR B 1 342 ? 146.082 117.396 160.266 1.00 72.67  ? 342 TYR D CB    1 
ATOM   4602 C CG    . TYR B 1 342 ? 147.577 117.493 160.078 1.00 76.00  ? 342 TYR D CG    1 
ATOM   4603 C CD1   . TYR B 1 342 ? 148.350 116.352 159.917 1.00 78.05  ? 342 TYR D CD1   1 
ATOM   4604 C CD2   . TYR B 1 342 ? 148.215 118.724 160.056 1.00 78.51  ? 342 TYR D CD2   1 
ATOM   4605 C CE1   . TYR B 1 342 ? 149.716 116.434 159.744 1.00 83.46  ? 342 TYR D CE1   1 
ATOM   4606 C CE2   . TYR B 1 342 ? 149.583 118.815 159.883 1.00 85.55  ? 342 TYR D CE2   1 
ATOM   4607 C CZ    . TYR B 1 342 ? 150.327 117.667 159.728 1.00 88.14  ? 342 TYR D CZ    1 
ATOM   4608 O OH    . TYR B 1 342 ? 151.689 117.749 159.554 1.00 92.40  ? 342 TYR D OH    1 
ATOM   4609 N N     . HIS B 1 343 ? 146.353 117.847 163.380 1.00 80.66  ? 343 HIS D N     1 
ATOM   4610 C CA    . HIS B 1 343 ? 147.148 118.117 164.573 1.00 80.27  ? 343 HIS D CA    1 
ATOM   4611 C C     . HIS B 1 343 ? 147.000 116.993 165.590 1.00 83.83  ? 343 HIS D C     1 
ATOM   4612 O O     . HIS B 1 343 ? 147.997 116.465 166.098 1.00 86.38  ? 343 HIS D O     1 
ATOM   4613 C CB    . HIS B 1 343 ? 146.724 119.456 165.179 1.00 82.56  ? 343 HIS D CB    1 
ATOM   4614 C CG    . HIS B 1 343 ? 147.375 119.769 166.492 1.00 95.63  ? 343 HIS D CG    1 
ATOM   4615 N ND1   . HIS B 1 343 ? 146.926 120.778 167.318 1.00 97.75  ? 343 HIS D ND1   1 
ATOM   4616 C CD2   . HIS B 1 343 ? 148.447 119.224 167.114 1.00 95.80  ? 343 HIS D CD2   1 
ATOM   4617 C CE1   . HIS B 1 343 ? 147.684 120.831 168.398 1.00 89.59  ? 343 HIS D CE1   1 
ATOM   4618 N NE2   . HIS B 1 343 ? 148.615 119.899 168.300 1.00 91.91  ? 343 HIS D NE2   1 
ATOM   4619 N N     . CYS B 1 344 ? 145.757 116.619 165.901 1.00 81.32  ? 344 CYS D N     1 
ATOM   4620 C CA    . CYS B 1 344 ? 145.514 115.636 166.952 1.00 83.27  ? 344 CYS D CA    1 
ATOM   4621 C C     . CYS B 1 344 ? 146.112 114.281 166.598 1.00 79.90  ? 344 CYS D C     1 
ATOM   4622 O O     . CYS B 1 344 ? 146.706 113.615 167.454 1.00 83.35  ? 344 CYS D O     1 
ATOM   4623 C CB    . CYS B 1 344 ? 144.013 115.505 167.205 1.00 85.83  ? 344 CYS D CB    1 
ATOM   4624 S SG    . CYS B 1 344 ? 143.241 116.975 167.921 1.00 91.29  ? 344 CYS D SG    1 
ATOM   4625 N N     . LEU B 1 345 ? 145.960 113.851 165.343 1.00 78.29  ? 345 LEU D N     1 
ATOM   4626 C CA    . LEU B 1 345 ? 146.431 112.525 164.958 1.00 78.96  ? 345 LEU D CA    1 
ATOM   4627 C C     . LEU B 1 345 ? 147.926 112.384 165.207 1.00 84.56  ? 345 LEU D C     1 
ATOM   4628 O O     . LEU B 1 345 ? 148.386 111.373 165.750 1.00 87.16  ? 345 LEU D O     1 
ATOM   4629 C CB    . LEU B 1 345 ? 146.106 112.261 163.486 1.00 75.11  ? 345 LEU D CB    1 
ATOM   4630 C CG    . LEU B 1 345 ? 144.715 111.726 163.135 1.00 66.96  ? 345 LEU D CG    1 
ATOM   4631 C CD1   . LEU B 1 345 ? 144.671 111.317 161.679 1.00 60.45  ? 345 LEU D CD1   1 
ATOM   4632 C CD2   . LEU B 1 345 ? 144.321 110.554 164.015 1.00 70.86  ? 345 LEU D CD2   1 
ATOM   4633 N N     . LYS B 1 346 ? 148.705 113.393 164.815 1.00 89.60  ? 346 LYS D N     1 
ATOM   4634 C CA    . LYS B 1 346 ? 150.146 113.332 165.023 1.00 92.77  ? 346 LYS D CA    1 
ATOM   4635 C C     . LYS B 1 346 ? 150.510 113.550 166.486 1.00 92.09  ? 346 LYS D C     1 
ATOM   4636 O O     . LYS B 1 346 ? 151.423 112.896 167.002 1.00 87.17  ? 346 LYS D O     1 
ATOM   4637 C CB    . LYS B 1 346 ? 150.847 114.365 164.143 1.00 93.86  ? 346 LYS D CB    1 
ATOM   4638 C CG    . LYS B 1 346 ? 152.361 114.300 164.215 1.00 97.68  ? 346 LYS D CG    1 
ATOM   4639 C CD    . LYS B 1 346 ? 153.005 115.280 163.253 1.00 98.94  ? 346 LYS D CD    1 
ATOM   4640 C CE    . LYS B 1 346 ? 154.520 115.230 163.346 1.00 101.42 ? 346 LYS D CE    1 
ATOM   4641 N NZ    . LYS B 1 346 ? 155.167 116.184 162.405 1.00 102.21 ? 346 LYS D NZ    1 
ATOM   4642 N N     . GLU B 1 347 ? 149.809 114.456 167.173 1.00 94.37  ? 347 GLU D N     1 
ATOM   4643 C CA    . GLU B 1 347 ? 150.142 114.737 168.565 1.00 95.95  ? 347 GLU D CA    1 
ATOM   4644 C C     . GLU B 1 347 ? 149.949 113.506 169.440 1.00 98.93  ? 347 GLU D C     1 
ATOM   4645 O O     . GLU B 1 347 ? 150.853 113.126 170.194 1.00 97.07  ? 347 GLU D O     1 
ATOM   4646 C CB    . GLU B 1 347 ? 149.288 115.898 169.077 1.00 95.54  ? 347 GLU D CB    1 
ATOM   4647 C CG    . GLU B 1 347 ? 149.608 116.333 170.496 1.00 99.84  ? 347 GLU D CG    1 
ATOM   4648 C CD    . GLU B 1 347 ? 148.762 117.506 170.948 1.00 100.71 ? 347 GLU D CD    1 
ATOM   4649 O OE1   . GLU B 1 347 ? 147.901 117.957 170.162 1.00 97.50  ? 347 GLU D OE1   1 
ATOM   4650 O OE2   . GLU B 1 347 ? 148.956 117.977 172.088 1.00 99.22  ? 347 GLU D OE2   1 
ATOM   4651 N N     . THR B 1 348 ? 148.785 112.860 169.346 1.00 102.14 ? 348 THR D N     1 
ATOM   4652 C CA    . THR B 1 348 ? 148.495 111.715 170.200 1.00 100.91 ? 348 THR D CA    1 
ATOM   4653 C C     . THR B 1 348 ? 149.373 110.512 169.889 1.00 100.60 ? 348 THR D C     1 
ATOM   4654 O O     . THR B 1 348 ? 149.446 109.594 170.713 1.00 100.37 ? 348 THR D O     1 
ATOM   4655 C CB    . THR B 1 348 ? 147.026 111.312 170.069 1.00 98.94  ? 348 THR D CB    1 
ATOM   4656 O OG1   . THR B 1 348 ? 146.708 110.332 171.064 1.00 93.89  ? 348 THR D OG1   1 
ATOM   4657 C CG2   . THR B 1 348 ? 146.747 110.735 168.688 1.00 98.05  ? 348 THR D CG2   1 
ATOM   4658 N N     . ALA B 1 349 ? 150.032 110.489 168.734 1.00 96.65  ? 349 ALA D N     1 
ATOM   4659 C CA    . ALA B 1 349 ? 150.915 109.392 168.368 1.00 98.37  ? 349 ALA D CA    1 
ATOM   4660 C C     . ALA B 1 349 ? 152.302 109.523 168.980 1.00 103.50 ? 349 ALA D C     1 
ATOM   4661 O O     . ALA B 1 349 ? 153.101 108.589 168.869 1.00 102.14 ? 349 ALA D O     1 
ATOM   4662 C CB    . ALA B 1 349 ? 151.033 109.300 166.843 1.00 94.43  ? 349 ALA D CB    1 
ATOM   4663 N N     . GLY B 1 350 ? 152.605 110.649 169.619 1.00 104.24 ? 350 GLY D N     1 
ATOM   4664 C CA    . GLY B 1 350 ? 153.902 110.852 170.237 1.00 99.57  ? 350 GLY D CA    1 
ATOM   4665 C C     . GLY B 1 350 ? 153.919 110.454 171.699 1.00 99.20  ? 350 GLY D C     1 
ATOM   4666 O O     . GLY B 1 350 ? 153.295 111.105 172.538 1.00 94.37  ? 350 GLY D O     1 
ATOM   4667 N N     . GLY C 1 291 ? 156.573 124.456 159.367 1.00 103.14 ? 291 GLY E N     1 
ATOM   4668 C CA    . GLY C 1 291 ? 155.323 124.983 158.853 1.00 107.20 ? 291 GLY E CA    1 
ATOM   4669 C C     . GLY C 1 291 ? 154.146 124.069 159.130 1.00 108.23 ? 291 GLY E C     1 
ATOM   4670 O O     . GLY C 1 291 ? 154.287 122.846 159.137 1.00 109.13 ? 291 GLY E O     1 
ATOM   4671 N N     . SER C 1 292 ? 152.982 124.665 159.358 1.00 105.66 ? 292 SER E N     1 
ATOM   4672 C CA    . SER C 1 292 ? 151.765 123.918 159.659 1.00 100.98 ? 292 SER E CA    1 
ATOM   4673 C C     . SER C 1 292 ? 150.597 124.895 159.633 1.00 99.72  ? 292 SER E C     1 
ATOM   4674 O O     . SER C 1 292 ? 150.776 126.105 159.461 1.00 100.63 ? 292 SER E O     1 
ATOM   4675 C CB    . SER C 1 292 ? 151.862 123.208 161.010 1.00 102.60 ? 292 SER E CB    1 
ATOM   4676 O OG    . SER C 1 292 ? 151.964 124.143 162.070 1.00 99.00  ? 292 SER E OG    1 
ATOM   4677 N N     . CYS C 1 293 ? 149.395 124.356 159.811 1.00 98.79  ? 293 CYS E N     1 
ATOM   4678 C CA    . CYS C 1 293 ? 148.175 125.146 159.854 1.00 97.46  ? 293 CYS E CA    1 
ATOM   4679 C C     . CYS C 1 293 ? 147.343 124.716 161.052 1.00 96.18  ? 293 CYS E C     1 
ATOM   4680 O O     . CYS C 1 293 ? 147.438 123.576 161.516 1.00 97.24  ? 293 CYS E O     1 
ATOM   4681 C CB    . CYS C 1 293 ? 147.358 124.986 158.569 1.00 92.43  ? 293 CYS E CB    1 
ATOM   4682 S SG    . CYS C 1 293 ? 146.841 123.289 158.248 1.00 101.47 ? 293 CYS E SG    1 
ATOM   4683 N N     . PHE C 1 294 ? 146.525 125.645 161.552 1.00 90.56  ? 294 PHE E N     1 
ATOM   4684 C CA    . PHE C 1 294 ? 145.693 125.403 162.724 1.00 90.11  ? 294 PHE E CA    1 
ATOM   4685 C C     . PHE C 1 294 ? 144.216 125.644 162.437 1.00 86.00  ? 294 PHE E C     1 
ATOM   4686 O O     . PHE C 1 294 ? 143.419 125.772 163.371 1.00 85.59  ? 294 PHE E O     1 
ATOM   4687 C CB    . PHE C 1 294 ? 146.156 126.280 163.887 1.00 91.71  ? 294 PHE E CB    1 
ATOM   4688 C CG    . PHE C 1 294 ? 147.534 125.952 164.377 1.00 96.94  ? 294 PHE E CG    1 
ATOM   4689 C CD1   . PHE C 1 294 ? 148.649 126.396 163.689 1.00 99.10  ? 294 PHE E CD1   1 
ATOM   4690 C CD2   . PHE C 1 294 ? 147.715 125.198 165.523 1.00 100.92 ? 294 PHE E CD2   1 
ATOM   4691 C CE1   . PHE C 1 294 ? 149.919 126.096 164.136 1.00 102.28 ? 294 PHE E CE1   1 
ATOM   4692 C CE2   . PHE C 1 294 ? 148.984 124.895 165.975 1.00 104.24 ? 294 PHE E CE2   1 
ATOM   4693 C CZ    . PHE C 1 294 ? 150.087 125.344 165.280 1.00 106.88 ? 294 PHE E CZ    1 
ATOM   4694 N N     . LEU C 1 295 ? 143.833 125.701 161.167 1.00 81.92  ? 295 LEU E N     1 
ATOM   4695 C CA    . LEU C 1 295 ? 142.444 125.943 160.818 1.00 78.54  ? 295 LEU E CA    1 
ATOM   4696 C C     . LEU C 1 295 ? 141.562 124.793 161.287 1.00 72.05  ? 295 LEU E C     1 
ATOM   4697 O O     . LEU C 1 295 ? 141.995 123.642 161.375 1.00 75.26  ? 295 LEU E O     1 
ATOM   4698 C CB    . LEU C 1 295 ? 142.300 126.122 159.307 1.00 80.61  ? 295 LEU E CB    1 
ATOM   4699 C CG    . LEU C 1 295 ? 142.949 127.370 158.710 1.00 89.47  ? 295 LEU E CG    1 
ATOM   4700 C CD1   . LEU C 1 295 ? 142.964 127.291 157.195 1.00 87.14  ? 295 LEU E CD1   1 
ATOM   4701 C CD2   . LEU C 1 295 ? 142.218 128.619 159.168 1.00 87.37  ? 295 LEU E CD2   1 
ATOM   4702 N N     . VAL C 1 296 ? 140.314 125.123 161.608 1.00 69.14  ? 296 VAL E N     1 
ATOM   4703 C CA    . VAL C 1 296 ? 139.293 124.123 161.889 1.00 67.99  ? 296 VAL E CA    1 
ATOM   4704 C C     . VAL C 1 296 ? 138.012 124.553 161.191 1.00 68.62  ? 296 VAL E C     1 
ATOM   4705 O O     . VAL C 1 296 ? 137.259 125.388 161.705 1.00 71.31  ? 296 VAL E O     1 
ATOM   4706 C CB    . VAL C 1 296 ? 139.072 123.941 163.400 1.00 69.19  ? 296 VAL E CB    1 
ATOM   4707 C CG1   . VAL C 1 296 ? 137.824 123.116 163.659 1.00 70.43  ? 296 VAL E CG1   1 
ATOM   4708 C CG2   . VAL C 1 296 ? 140.280 123.278 164.034 1.00 70.61  ? 296 VAL E CG2   1 
ATOM   4709 N N     . VAL C 1 297 ? 137.753 123.978 160.019 1.00 68.09  ? 297 VAL E N     1 
ATOM   4710 C CA    . VAL C 1 297 ? 136.603 124.385 159.226 1.00 65.47  ? 297 VAL E CA    1 
ATOM   4711 C C     . VAL C 1 297 ? 135.317 124.000 159.944 1.00 65.91  ? 297 VAL E C     1 
ATOM   4712 O O     . VAL C 1 297 ? 135.270 123.036 160.719 1.00 66.98  ? 297 VAL E O     1 
ATOM   4713 C CB    . VAL C 1 297 ? 136.669 123.748 157.826 1.00 61.96  ? 297 VAL E CB    1 
ATOM   4714 C CG1   . VAL C 1 297 ? 135.504 124.221 156.972 1.00 63.67  ? 297 VAL E CG1   1 
ATOM   4715 C CG2   . VAL C 1 297 ? 137.996 124.072 157.159 1.00 61.32  ? 297 VAL E CG2   1 
ATOM   4716 N N     . ALA C 1 298 ? 134.260 124.766 159.690 1.00 69.70  ? 298 ALA E N     1 
ATOM   4717 C CA    . ALA C 1 298 ? 132.956 124.433 160.242 1.00 77.97  ? 298 ALA E CA    1 
ATOM   4718 C C     . ALA C 1 298 ? 132.470 123.111 159.665 1.00 77.86  ? 298 ALA E C     1 
ATOM   4719 O O     . ALA C 1 298 ? 132.626 122.840 158.471 1.00 73.53  ? 298 ALA E O     1 
ATOM   4720 C CB    . ALA C 1 298 ? 131.952 125.544 159.938 1.00 77.55  ? 298 ALA E CB    1 
ATOM   4721 N N     . SER C 1 299 ? 131.879 122.280 160.520 1.00 78.49  ? 299 SER E N     1 
ATOM   4722 C CA    . SER C 1 299 ? 131.406 120.974 160.087 1.00 79.25  ? 299 SER E CA    1 
ATOM   4723 C C     . SER C 1 299 ? 130.423 120.430 161.111 1.00 82.10  ? 299 SER E C     1 
ATOM   4724 O O     . SER C 1 299 ? 130.566 120.662 162.314 1.00 85.42  ? 299 SER E O     1 
ATOM   4725 C CB    . SER C 1 299 ? 132.570 119.996 159.896 1.00 75.04  ? 299 SER E CB    1 
ATOM   4726 O OG    . SER C 1 299 ? 133.112 119.598 161.142 1.00 74.35  ? 299 SER E OG    1 
ATOM   4727 N N     . HIS C 1 300 ? 129.425 119.701 160.615 1.00 83.41  ? 300 HIS E N     1 
ATOM   4728 C CA    . HIS C 1 300 ? 128.438 119.036 161.464 1.00 87.68  ? 300 HIS E CA    1 
ATOM   4729 C C     . HIS C 1 300 ? 127.756 120.023 162.407 1.00 93.01  ? 300 HIS E C     1 
ATOM   4730 O O     . HIS C 1 300 ? 127.509 119.724 163.577 1.00 90.18  ? 300 HIS E O     1 
ATOM   4731 C CB    . HIS C 1 300 ? 129.079 117.891 162.250 1.00 87.31  ? 300 HIS E CB    1 
ATOM   4732 C CG    . HIS C 1 300 ? 129.853 116.935 161.399 1.00 88.50  ? 300 HIS E CG    1 
ATOM   4733 N ND1   . HIS C 1 300 ? 131.222 117.002 161.260 1.00 87.82  ? 300 HIS E ND1   1 
ATOM   4734 C CD2   . HIS C 1 300 ? 129.448 115.893 160.636 1.00 85.02  ? 300 HIS E CD2   1 
ATOM   4735 C CE1   . HIS C 1 300 ? 131.628 116.038 160.453 1.00 79.02  ? 300 HIS E CE1   1 
ATOM   4736 N NE2   . HIS C 1 300 ? 130.571 115.351 160.060 1.00 78.62  ? 300 HIS E NE2   1 
ATOM   4737 N N     . GLY C 1 301 ? 127.446 121.212 161.895 1.00 93.05  ? 301 GLY E N     1 
ATOM   4738 C CA    . GLY C 1 301 ? 126.773 122.225 162.678 1.00 95.46  ? 301 GLY E CA    1 
ATOM   4739 C C     . GLY C 1 301 ? 127.671 123.040 163.581 1.00 95.17  ? 301 GLY E C     1 
ATOM   4740 O O     . GLY C 1 301 ? 127.179 123.959 164.248 1.00 94.66  ? 301 GLY E O     1 
ATOM   4741 N N     . LEU C 1 302 ? 128.965 122.742 163.627 1.00 95.48  ? 302 LEU E N     1 
ATOM   4742 C CA    . LEU C 1 302 ? 129.888 123.518 164.435 1.00 91.69  ? 302 LEU E CA    1 
ATOM   4743 C C     . LEU C 1 302 ? 130.156 124.868 163.774 1.00 88.45  ? 302 LEU E C     1 
ATOM   4744 O O     . LEU C 1 302 ? 129.606 125.199 162.719 1.00 89.51  ? 302 LEU E O     1 
ATOM   4745 C CB    . LEU C 1 302 ? 131.196 122.755 164.636 1.00 90.55  ? 302 LEU E CB    1 
ATOM   4746 C CG    . LEU C 1 302 ? 131.123 121.528 165.546 1.00 94.49  ? 302 LEU E CG    1 
ATOM   4747 C CD1   . LEU C 1 302 ? 132.268 120.572 165.239 1.00 91.87  ? 302 LEU E CD1   1 
ATOM   4748 C CD2   . LEU C 1 302 ? 131.141 121.940 167.008 1.00 92.79  ? 302 LEU E CD2   1 
ATOM   4749 N N     . SER C 1 303 ? 131.009 125.656 164.417 1.00 88.49  ? 303 SER E N     1 
ATOM   4750 C CA    . SER C 1 303 ? 131.398 126.967 163.920 1.00 90.61  ? 303 SER E CA    1 
ATOM   4751 C C     . SER C 1 303 ? 132.868 126.957 163.521 1.00 83.84  ? 303 SER E C     1 
ATOM   4752 O O     . SER C 1 303 ? 133.700 126.334 164.187 1.00 81.61  ? 303 SER E O     1 
ATOM   4753 C CB    . SER C 1 303 ? 131.147 128.040 164.978 1.00 97.84  ? 303 SER E CB    1 
ATOM   4754 O OG    . SER C 1 303 ? 129.987 127.745 165.736 1.00 97.47  ? 303 SER E OG    1 
ATOM   4755 N N     . ALA C 1 304 ? 133.178 127.651 162.431 1.00 82.77  ? 304 ALA E N     1 
ATOM   4756 C CA    . ALA C 1 304 ? 134.541 127.692 161.925 1.00 81.14  ? 304 ALA E CA    1 
ATOM   4757 C C     . ALA C 1 304 ? 135.460 128.425 162.896 1.00 82.40  ? 304 ALA E C     1 
ATOM   4758 O O     . ALA C 1 304 ? 135.036 129.305 163.648 1.00 83.39  ? 304 ALA E O     1 
ATOM   4759 C CB    . ALA C 1 304 ? 134.581 128.375 160.559 1.00 74.57  ? 304 ALA E CB    1 
ATOM   4760 N N     . ILE C 1 305 ? 136.735 128.047 162.871 1.00 77.87  ? 305 ILE E N     1 
ATOM   4761 C CA    . ILE C 1 305 ? 137.769 128.671 163.686 1.00 75.39  ? 305 ILE E CA    1 
ATOM   4762 C C     . ILE C 1 305 ? 138.884 129.128 162.759 1.00 79.74  ? 305 ILE E C     1 
ATOM   4763 O O     . ILE C 1 305 ? 139.368 128.348 161.932 1.00 83.88  ? 305 ILE E O     1 
ATOM   4764 C CB    . ILE C 1 305 ? 138.312 127.705 164.755 1.00 75.59  ? 305 ILE E CB    1 
ATOM   4765 C CG1   . ILE C 1 305 ? 137.251 127.440 165.823 1.00 78.22  ? 305 ILE E CG1   1 
ATOM   4766 C CG2   . ILE C 1 305 ? 139.574 128.266 165.388 1.00 77.72  ? 305 ILE E CG2   1 
ATOM   4767 C CD1   . ILE C 1 305 ? 137.495 126.177 166.627 1.00 76.07  ? 305 ILE E CD1   1 
ATOM   4768 N N     . ALA C 1 306 ? 139.284 130.392 162.891 1.00 86.47  ? 306 ALA E N     1 
ATOM   4769 C CA    . ALA C 1 306 ? 140.384 130.897 162.078 1.00 85.62  ? 306 ALA E CA    1 
ATOM   4770 C C     . ALA C 1 306 ? 141.729 130.386 162.578 1.00 84.20  ? 306 ALA E C     1 
ATOM   4771 O O     . ALA C 1 306 ? 142.693 130.329 161.808 1.00 78.58  ? 306 ALA E O     1 
ATOM   4772 C CB    . ALA C 1 306 ? 140.367 132.425 162.066 1.00 87.99  ? 306 ALA E CB    1 
ATOM   4773 N N     . ASP C 1 307 ? 141.815 130.018 163.854 1.00 86.98  ? 307 ASP E N     1 
ATOM   4774 C CA    . ASP C 1 307 ? 143.058 129.522 164.428 1.00 91.20  ? 307 ASP E CA    1 
ATOM   4775 C C     . ASP C 1 307 ? 142.748 128.881 165.771 1.00 92.65  ? 307 ASP E C     1 
ATOM   4776 O O     . ASP C 1 307 ? 142.065 129.486 166.603 1.00 91.53  ? 307 ASP E O     1 
ATOM   4777 C CB    . ASP C 1 307 ? 144.077 130.654 164.595 1.00 95.22  ? 307 ASP E CB    1 
ATOM   4778 C CG    . ASP C 1 307 ? 145.444 130.154 165.020 1.00 95.62  ? 307 ASP E CG    1 
ATOM   4779 O OD1   . ASP C 1 307 ? 145.526 129.426 166.032 1.00 93.37  ? 307 ASP E OD1   1 
ATOM   4780 O OD2   . ASP C 1 307 ? 146.439 130.491 164.345 1.00 99.01  ? 307 ASP E OD2   1 
ATOM   4781 N N     . SER C 1 308 ? 143.247 127.660 165.974 1.00 94.01  ? 308 SER E N     1 
ATOM   4782 C CA    . SER C 1 308 ? 142.989 126.953 167.225 1.00 92.97  ? 308 SER E CA    1 
ATOM   4783 C C     . SER C 1 308 ? 143.637 127.660 168.409 1.00 97.88  ? 308 SER E C     1 
ATOM   4784 O O     . SER C 1 308 ? 143.030 127.773 169.481 1.00 98.68  ? 308 SER E O     1 
ATOM   4785 C CB    . SER C 1 308 ? 143.493 125.515 167.124 1.00 87.27  ? 308 SER E CB    1 
ATOM   4786 O OG    . SER C 1 308 ? 142.701 124.642 167.908 1.00 86.44  ? 308 SER E OG    1 
ATOM   4787 N N     . ARG C 1 309 ? 144.871 128.140 168.239 1.00 99.03  ? 309 ARG E N     1 
ATOM   4788 C CA    . ARG C 1 309 ? 145.593 128.729 169.363 1.00 99.25  ? 309 ARG E CA    1 
ATOM   4789 C C     . ARG C 1 309 ? 144.913 129.998 169.862 1.00 98.28  ? 309 ARG E C     1 
ATOM   4790 O O     . ARG C 1 309 ? 144.784 130.204 171.075 1.00 95.23  ? 309 ARG E O     1 
ATOM   4791 C CB    . ARG C 1 309 ? 147.037 129.021 168.959 1.00 100.98 ? 309 ARG E CB    1 
ATOM   4792 C CG    . ARG C 1 309 ? 147.927 127.787 168.916 1.00 102.56 ? 309 ARG E CG    1 
ATOM   4793 C CD    . ARG C 1 309 ? 148.939 127.857 167.783 1.00 100.60 ? 309 ARG E CD    1 
ATOM   4794 N NE    . ARG C 1 309 ? 149.478 129.200 167.607 1.00 100.44 ? 309 ARG E NE    1 
ATOM   4795 C CZ    . ARG C 1 309 ? 150.220 129.839 168.502 1.00 103.31 ? 309 ARG E CZ    1 
ATOM   4796 N NH1   . ARG C 1 309 ? 150.552 129.278 169.654 1.00 105.82 ? 309 ARG E NH1   1 
ATOM   4797 N NH2   . ARG C 1 309 ? 150.641 131.071 168.234 1.00 105.17 ? 309 ARG E NH2   1 
ATOM   4798 N N     . ILE C 1 310 ? 144.468 130.861 168.945 1.00 99.10  ? 310 ILE E N     1 
ATOM   4799 C CA    . ILE C 1 310 ? 143.901 132.142 169.350 1.00 99.98  ? 310 ILE E CA    1 
ATOM   4800 C C     . ILE C 1 310 ? 142.618 131.965 170.150 1.00 98.56  ? 310 ILE E C     1 
ATOM   4801 O O     . ILE C 1 310 ? 142.313 132.796 171.013 1.00 97.70  ? 310 ILE E O     1 
ATOM   4802 C CB    . ILE C 1 310 ? 143.649 133.036 168.121 1.00 99.04  ? 310 ILE E CB    1 
ATOM   4803 C CG1   . ILE C 1 310 ? 144.978 133.408 167.456 1.00 98.95  ? 310 ILE E CG1   1 
ATOM   4804 C CG2   . ILE C 1 310 ? 142.884 134.293 168.525 1.00 97.19  ? 310 ILE E CG2   1 
ATOM   4805 C CD1   . ILE C 1 310 ? 144.831 134.003 166.069 1.00 97.99  ? 310 ILE E CD1   1 
ATOM   4806 N N     . GLU C 1 311 ? 141.855 130.910 169.888 1.00 98.89  ? 311 GLU E N     1 
ATOM   4807 C CA    . GLU C 1 311 ? 140.623 130.657 170.626 1.00 98.06  ? 311 GLU E CA    1 
ATOM   4808 C C     . GLU C 1 311 ? 140.921 130.407 172.101 1.00 93.80  ? 311 GLU E C     1 
ATOM   4809 O O     . GLU C 1 311 ? 141.661 129.486 172.448 1.00 92.81  ? 311 GLU E O     1 
ATOM   4810 C CB    . GLU C 1 311 ? 139.878 129.461 170.032 1.00 97.87  ? 311 GLU E CB    1 
ATOM   4811 C CG    . GLU C 1 311 ? 139.265 129.726 168.667 1.00 96.05  ? 311 GLU E CG    1 
ATOM   4812 C CD    . GLU C 1 311 ? 138.094 130.686 168.724 1.00 95.10  ? 311 GLU E CD    1 
ATOM   4813 O OE1   . GLU C 1 311 ? 137.215 130.501 169.593 1.00 92.52  ? 311 GLU E OE1   1 
ATOM   4814 O OE2   . GLU C 1 311 ? 138.050 131.621 167.898 1.00 87.48  ? 311 GLU E OE2   1 
HETATM 4815 N N1    . P5P D 2 1   ? 114.015 111.512 140.276 1.00 175.43 ? 3   P5P O N1    1 
HETATM 4816 C C2    . P5P D 2 1   ? 113.691 110.239 140.018 1.00 178.36 ? 3   P5P O C2    1 
HETATM 4817 N N3    . P5P D 2 1   ? 114.242 109.124 140.485 1.00 178.46 ? 3   P5P O N3    1 
HETATM 4818 C C4    . P5P D 2 1   ? 115.252 109.410 141.324 1.00 179.36 ? 3   P5P O C4    1 
HETATM 4819 C C5    . P5P D 2 1   ? 115.706 110.663 141.687 1.00 176.70 ? 3   P5P O C5    1 
HETATM 4820 C C6    . P5P D 2 1   ? 115.037 111.764 141.123 1.00 173.54 ? 3   P5P O C6    1 
HETATM 4821 N N7    . P5P D 2 1   ? 116.771 110.559 142.573 1.00 179.92 ? 3   P5P O N7    1 
HETATM 4822 C C8    . P5P D 2 1   ? 116.935 109.266 142.720 1.00 181.46 ? 3   P5P O C8    1 
HETATM 4823 N N9    . P5P D 2 1   ? 116.043 108.514 141.996 1.00 183.88 ? 3   P5P O N9    1 
HETATM 4824 C "C1'" . P5P D 2 1   ? 115.937 107.048 141.898 1.00 183.52 ? 3   P5P O "C1'" 1 
HETATM 4825 C "C2'" . P5P D 2 1   ? 116.442 106.555 140.543 1.00 181.28 ? 3   P5P O "C2'" 1 
HETATM 4826 O "O2'" . P5P D 2 1   ? 115.765 105.354 140.203 1.00 178.00 ? 3   P5P O "O2'" 1 
HETATM 4827 C "C3'" . P5P D 2 1   ? 117.907 106.295 140.855 1.00 182.67 ? 3   P5P O "C3'" 1 
HETATM 4828 O "O3'" . P5P D 2 1   ? 118.543 105.432 139.929 1.00 186.38 ? 3   P5P O "O3'" 1 
HETATM 4829 C "C4'" . P5P D 2 1   ? 117.842 105.728 142.266 1.00 180.42 ? 3   P5P O "C4'" 1 
HETATM 4830 O "O4'" . P5P D 2 1   ? 116.757 106.468 142.890 1.00 183.96 ? 3   P5P O "O4'" 1 
HETATM 4831 C "C5'" . P5P D 2 1   ? 119.090 105.871 143.099 1.00 176.56 ? 3   P5P O "C5'" 1 
HETATM 4832 O "O5'" . P5P D 2 1   ? 119.058 107.054 143.882 1.00 173.76 ? 3   P5P O "O5'" 1 
HETATM 4833 P P     . P5P D 2 1   ? 118.932 106.980 145.468 1.00 168.05 ? 3   P5P O P     1 
HETATM 4834 O OP1   . P5P D 2 1   ? 117.917 105.948 145.803 1.00 174.59 ? 3   P5P O OP1   1 
HETATM 4835 O OP2   . P5P D 2 1   ? 120.300 106.873 146.036 1.00 170.12 ? 3   P5P O OP2   1 
HETATM 4836 N N1    . P5P D 2 2   ? 116.322 114.006 137.657 1.00 174.06 ? 4   P5P O N1    1 
HETATM 4837 C C2    . P5P D 2 2   ? 115.417 113.345 136.925 1.00 173.34 ? 4   P5P O C2    1 
HETATM 4838 N N3    . P5P D 2 2   ? 115.200 112.034 136.842 1.00 174.97 ? 4   P5P O N3    1 
HETATM 4839 C C4    . P5P D 2 2   ? 116.048 111.358 137.637 1.00 178.32 ? 4   P5P O C4    1 
HETATM 4840 C C5    . P5P D 2 2   ? 117.033 111.896 138.445 1.00 177.01 ? 4   P5P O C5    1 
HETATM 4841 C C6    . P5P D 2 2   ? 117.161 113.298 138.445 1.00 174.21 ? 4   P5P O C6    1 
HETATM 4842 N N7    . P5P D 2 2   ? 117.714 110.892 139.119 1.00 175.82 ? 4   P5P O N7    1 
HETATM 4843 C C8    . P5P D 2 2   ? 117.140 109.787 138.706 1.00 177.80 ? 4   P5P O C8    1 
HETATM 4844 N N9    . P5P D 2 2   ? 116.121 109.997 137.810 1.00 180.23 ? 4   P5P O N9    1 
HETATM 4845 C "C1'" . P5P D 2 2   ? 115.278 108.988 137.140 1.00 180.89 ? 4   P5P O "C1'" 1 
HETATM 4846 C "C2'" . P5P D 2 2   ? 115.539 108.952 135.635 1.00 178.32 ? 4   P5P O "C2'" 1 
HETATM 4847 O "O2'" . P5P D 2 2   ? 114.354 108.537 134.971 1.00 177.06 ? 4   P5P O "O2'" 1 
HETATM 4848 C "C3'" . P5P D 2 2   ? 116.621 107.885 135.550 1.00 179.84 ? 4   P5P O "C3'" 1 
HETATM 4849 O "O3'" . P5P D 2 2   ? 116.763 107.314 134.261 1.00 178.41 ? 4   P5P O "O3'" 1 
HETATM 4850 C "C4'" . P5P D 2 2   ? 116.174 106.885 136.605 1.00 180.80 ? 4   P5P O "C4'" 1 
HETATM 4851 O "O4'" . P5P D 2 2   ? 115.607 107.714 137.656 1.00 183.14 ? 4   P5P O "O4'" 1 
HETATM 4852 C "C5'" . P5P D 2 2   ? 117.251 105.998 137.177 1.00 181.14 ? 4   P5P O "C5'" 1 
HETATM 4853 O "O5'" . P5P D 2 2   ? 118.280 106.755 137.795 1.00 185.61 ? 4   P5P O "O5'" 1 
HETATM 4854 P P     . P5P D 2 2   ? 119.382 106.048 138.703 1.00 193.88 ? 4   P5P O P     1 
HETATM 4855 O OP1   . P5P D 2 2   ? 119.964 104.923 137.928 1.00 183.83 ? 4   P5P O OP1   1 
HETATM 4856 O OP2   . P5P D 2 2   ? 120.275 107.105 139.244 1.00 189.10 ? 4   P5P O OP2   1 
HETATM 4857 N N1    . P5P D 2 3   ? 118.969 116.187 135.263 1.00 165.18 ? 5   P5P O N1    1 
HETATM 4858 C C2    . P5P D 2 3   ? 118.000 116.261 134.342 1.00 164.75 ? 5   P5P O C2    1 
HETATM 4859 N N3    . P5P D 2 3   ? 117.230 115.292 133.852 1.00 166.30 ? 5   P5P O N3    1 
HETATM 4860 C C4    . P5P D 2 3   ? 117.534 114.111 134.417 1.00 170.13 ? 5   P5P O C4    1 
HETATM 4861 C C5    . P5P D 2 3   ? 118.504 113.876 135.374 1.00 171.68 ? 5   P5P O C5    1 
HETATM 4862 C C6    . P5P D 2 3   ? 119.252 114.983 135.809 1.00 167.52 ? 5   P5P O C6    1 
HETATM 4863 N N7    . P5P D 2 3   ? 118.536 112.534 135.722 1.00 172.87 ? 5   P5P O N7    1 
HETATM 4864 C C8    . P5P D 2 3   ? 117.605 111.995 134.973 1.00 173.69 ? 5   P5P O C8    1 
HETATM 4865 N N9    . P5P D 2 3   ? 116.956 112.891 134.162 1.00 172.49 ? 5   P5P O N9    1 
HETATM 4866 C "C1'" . P5P D 2 3   ? 115.862 112.628 133.207 1.00 173.93 ? 5   P5P O "C1'" 1 
HETATM 4867 C "C2'" . P5P D 2 3   ? 116.233 113.033 131.781 1.00 172.11 ? 5   P5P O "C2'" 1 
HETATM 4868 O "O2'" . P5P D 2 3   ? 115.067 113.495 131.114 1.00 171.26 ? 5   P5P O "O2'" 1 
HETATM 4869 C "C3'" . P5P D 2 3   ? 116.711 111.708 131.204 1.00 173.83 ? 5   P5P O "C3'" 1 
HETATM 4870 O "O3'" . P5P D 2 3   ? 116.667 111.656 129.789 1.00 175.24 ? 5   P5P O "O3'" 1 
HETATM 4871 C "C4'" . P5P D 2 3   ? 115.781 110.705 131.867 1.00 174.39 ? 5   P5P O "C4'" 1 
HETATM 4872 O "O4'" . P5P D 2 3   ? 115.582 111.242 133.201 1.00 175.29 ? 5   P5P O "O4'" 1 
HETATM 4873 C "C5'" . P5P D 2 3   ? 116.285 109.285 131.950 1.00 172.77 ? 5   P5P O "C5'" 1 
HETATM 4874 O "O5'" . P5P D 2 3   ? 117.467 109.191 132.731 1.00 174.66 ? 5   P5P O "O5'" 1 
HETATM 4875 P P     . P5P D 2 3   ? 117.959 107.785 133.295 1.00 179.83 ? 5   P5P O P     1 
HETATM 4876 O OP1   . P5P D 2 3   ? 118.027 106.834 132.157 1.00 169.74 ? 5   P5P O OP1   1 
HETATM 4877 O OP2   . P5P D 2 3   ? 119.167 108.018 134.127 1.00 175.91 ? 5   P5P O OP2   1 
HETATM 4878 N N1    . P5P D 2 4   ? 123.314 119.225 134.232 1.00 139.11 ? 6   P5P O N1    1 
HETATM 4879 C C2    . P5P D 2 4   ? 122.480 119.784 133.345 1.00 142.48 ? 6   P5P O C2    1 
HETATM 4880 N N3    . P5P D 2 4   ? 121.509 119.220 132.631 1.00 146.65 ? 6   P5P O N3    1 
HETATM 4881 C C4    . P5P D 2 4   ? 121.422 117.907 132.900 1.00 149.12 ? 6   P5P O C4    1 
HETATM 4882 C C5    . P5P D 2 4   ? 122.210 117.190 133.783 1.00 147.77 ? 6   P5P O C5    1 
HETATM 4883 C C6    . P5P D 2 4   ? 123.203 117.901 134.478 1.00 143.03 ? 6   P5P O C6    1 
HETATM 4884 N N7    . P5P D 2 4   ? 121.838 115.854 133.802 1.00 148.29 ? 6   P5P O N7    1 
HETATM 4885 C C8    . P5P D 2 4   ? 120.854 115.792 132.940 1.00 153.20 ? 6   P5P O C8    1 
HETATM 4886 N N9    . P5P D 2 4   ? 120.552 116.996 132.353 1.00 152.48 ? 6   P5P O N9    1 
HETATM 4887 C "C1'" . P5P D 2 4   ? 119.489 117.256 131.363 1.00 155.48 ? 6   P5P O "C1'" 1 
HETATM 4888 C "C2'" . P5P D 2 4   ? 120.004 117.963 130.110 1.00 154.23 ? 6   P5P O "C2'" 1 
HETATM 4889 O "O2'" . P5P D 2 4   ? 118.982 118.816 129.614 1.00 153.29 ? 6   P5P O "O2'" 1 
HETATM 4890 C "C3'" . P5P D 2 4   ? 120.243 116.788 129.171 1.00 158.05 ? 6   P5P O "C3'" 1 
HETATM 4891 O "O3'" . P5P D 2 4   ? 120.233 117.150 127.802 1.00 163.66 ? 6   P5P O "O3'" 1 
HETATM 4892 C "C4'" . P5P D 2 4   ? 119.120 115.828 129.538 1.00 159.89 ? 6   P5P O "C4'" 1 
HETATM 4893 O "O4'" . P5P D 2 4   ? 118.937 116.020 130.964 1.00 160.84 ? 6   P5P O "O4'" 1 
HETATM 4894 C "C5'" . P5P D 2 4   ? 119.383 114.371 129.253 1.00 160.10 ? 6   P5P O "C5'" 1 
HETATM 4895 O "O5'" . P5P D 2 4   ? 118.323 113.552 129.721 1.00 166.72 ? 6   P5P O "O5'" 1 
HETATM 4896 P P     . P5P D 2 4   ? 117.890 112.241 128.927 1.00 173.35 ? 6   P5P O P     1 
HETATM 4897 O OP1   . P5P D 2 4   ? 117.361 112.660 127.603 1.00 159.64 ? 6   P5P O OP1   1 
HETATM 4898 O OP2   . P5P D 2 4   ? 119.009 111.269 128.998 1.00 160.88 ? 6   P5P O OP2   1 
HETATM 4899 N N1    . P5P D 2 5   ? 126.453 114.592 133.530 1.00 121.83 ? 7   P5P O N1    1 
HETATM 4900 C C2    . P5P D 2 5   ? 126.870 115.865 133.503 1.00 126.33 ? 7   P5P O C2    1 
HETATM 4901 N N3    . P5P D 2 5   ? 126.439 116.877 132.753 1.00 134.80 ? 7   P5P O N3    1 
HETATM 4902 C C4    . P5P D 2 5   ? 125.448 116.476 131.940 1.00 134.37 ? 7   P5P O C4    1 
HETATM 4903 C C5    . P5P D 2 5   ? 124.912 115.204 131.854 1.00 128.45 ? 7   P5P O C5    1 
HETATM 4904 C C6    . P5P D 2 5   ? 125.455 114.222 132.700 1.00 118.40 ? 7   P5P O C6    1 
HETATM 4905 N N7    . P5P D 2 5   ? 123.902 115.158 130.905 1.00 134.37 ? 7   P5P O N7    1 
HETATM 4906 C C8    . P5P D 2 5   ? 123.850 116.383 130.445 1.00 138.71 ? 7   P5P O C8    1 
HETATM 4907 N N9    . P5P D 2 5   ? 124.761 117.233 131.021 1.00 135.92 ? 7   P5P O N9    1 
HETATM 4908 C "C1'" . P5P D 2 5   ? 124.936 118.669 130.733 1.00 134.71 ? 7   P5P O "C1'" 1 
HETATM 4909 C "C2'" . P5P D 2 5   ? 126.029 118.939 129.702 1.00 132.77 ? 7   P5P O "C2'" 1 
HETATM 4910 O "O2'" . P5P D 2 5   ? 126.629 120.195 129.984 1.00 131.54 ? 7   P5P O "O2'" 1 
HETATM 4911 C "C3'" . P5P D 2 5   ? 125.227 118.986 128.409 1.00 139.99 ? 7   P5P O "C3'" 1 
HETATM 4912 O "O3'" . P5P D 2 5   ? 125.857 119.714 127.370 1.00 144.77 ? 7   P5P O "O3'" 1 
HETATM 4913 C "C4'" . P5P D 2 5   ? 123.906 119.608 128.842 1.00 140.00 ? 7   P5P O "C4'" 1 
HETATM 4914 O "O4'" . P5P D 2 5   ? 123.721 119.156 130.208 1.00 137.99 ? 7   P5P O "O4'" 1 
HETATM 4915 C "C5'" . P5P D 2 5   ? 122.712 119.201 128.019 1.00 143.58 ? 7   P5P O "C5'" 1 
HETATM 4916 O "O5'" . P5P D 2 5   ? 122.668 117.790 127.869 1.00 151.47 ? 7   P5P O "O5'" 1 
HETATM 4917 P P     . P5P D 2 5   ? 121.585 117.086 126.939 1.00 167.64 ? 7   P5P O P     1 
HETATM 4918 O OP1   . P5P D 2 5   ? 121.402 117.923 125.726 1.00 159.47 ? 7   P5P O OP1   1 
HETATM 4919 O OP2   . P5P D 2 5   ? 121.979 115.661 126.804 1.00 145.95 ? 7   P5P O OP2   1 
HETATM 4920 P P     . Y5P D 2 6   ? 126.904 118.979 126.401 1.00 149.12 ? 8   Y5P O P     1 
HETATM 4921 C "C5'" . Y5P D 2 6   ? 128.537 116.990 126.890 1.00 136.44 ? 8   Y5P O "C5'" 1 
HETATM 4922 O "O5'" . Y5P D 2 6   ? 127.385 117.729 127.259 1.00 144.51 ? 8   Y5P O "O5'" 1 
HETATM 4923 C "C4'" . Y5P D 2 6   ? 129.370 116.638 128.095 1.00 133.42 ? 8   Y5P O "C4'" 1 
HETATM 4924 O "O4'" . Y5P D 2 6   ? 128.529 116.059 129.125 1.00 132.00 ? 8   Y5P O "O4'" 1 
HETATM 4925 C "C3'" . Y5P D 2 6   ? 130.453 115.597 127.871 1.00 129.66 ? 8   Y5P O "C3'" 1 
HETATM 4926 O "O3'" . Y5P D 2 6   ? 131.625 116.146 127.297 1.00 133.49 ? 8   Y5P O "O3'" 1 
HETATM 4927 C "C2'" . Y5P D 2 6   ? 130.666 115.034 129.270 1.00 126.96 ? 8   Y5P O "C2'" 1 
HETATM 4928 O "O2'" . Y5P D 2 6   ? 131.495 115.887 130.047 1.00 122.07 ? 8   Y5P O "O2'" 1 
HETATM 4929 C "C1'" . Y5P D 2 6   ? 129.247 115.075 129.836 1.00 128.09 ? 8   Y5P O "C1'" 1 
HETATM 4930 N N1    . Y5P D 2 6   ? 128.545 113.780 129.694 1.00 127.77 ? 8   Y5P O N1    1 
HETATM 4931 C C2    . Y5P D 2 6   ? 128.934 112.749 130.526 1.00 121.65 ? 8   Y5P O C2    1 
HETATM 4932 N N3    . Y5P D 2 6   ? 128.245 111.577 130.352 1.00 115.15 ? 8   Y5P O N3    1 
HETATM 4933 C C4    . Y5P D 2 6   ? 127.226 111.339 129.454 1.00 117.98 ? 8   Y5P O C4    1 
HETATM 4934 C C6    . Y5P D 2 6   ? 127.533 113.612 128.779 1.00 124.41 ? 8   Y5P O C6    1 
HETATM 4935 O OP1   . Y5P D 2 6   ? 128.071 119.877 126.207 1.00 132.79 ? 8   Y5P O OP1   1 
HETATM 4936 O OP2   . Y5P D 2 6   ? 126.158 118.471 125.223 1.00 138.32 ? 8   Y5P O OP2   1 
HETATM 4937 C C5    . Y5P D 2 6   ? 126.875 112.457 128.630 1.00 120.34 ? 8   Y5P O C5    1 
HETATM 4938 P P     . Y5P D 2 7   ? 131.912 115.982 125.725 1.00 142.23 ? 9   Y5P O P     1 
HETATM 4939 C "C5'" . Y5P D 2 7   ? 134.434 116.285 126.362 1.00 117.25 ? 9   Y5P O "C5'" 1 
HETATM 4940 O "O5'" . Y5P D 2 7   ? 133.340 116.657 125.533 1.00 121.04 ? 9   Y5P O "O5'" 1 
HETATM 4941 C "C4'" . Y5P D 2 7   ? 135.731 116.872 125.866 1.00 116.46 ? 9   Y5P O "C4'" 1 
HETATM 4942 O "O4'" . Y5P D 2 7   ? 135.943 116.449 124.491 1.00 117.56 ? 9   Y5P O "O4'" 1 
HETATM 4943 C "C3'" . Y5P D 2 7   ? 135.786 118.397 125.854 1.00 116.21 ? 9   Y5P O "C3'" 1 
HETATM 4944 O "O3'" . Y5P D 2 7   ? 137.114 118.841 126.133 1.00 114.30 ? 9   Y5P O "O3'" 1 
HETATM 4945 C "C2'" . Y5P D 2 7   ? 135.422 118.735 124.413 1.00 114.85 ? 9   Y5P O "C2'" 1 
HETATM 4946 O "O2'" . Y5P D 2 7   ? 135.888 119.990 123.969 1.00 110.36 ? 9   Y5P O "O2'" 1 
HETATM 4947 C "C1'" . Y5P D 2 7   ? 136.081 117.584 123.658 1.00 113.11 ? 9   Y5P O "C1'" 1 
HETATM 4948 N N1    . Y5P D 2 7   ? 135.468 117.278 122.356 1.00 107.98 ? 9   Y5P O N1    1 
HETATM 4949 C C2    . Y5P D 2 7   ? 136.287 117.240 121.242 1.00 106.05 ? 9   Y5P O C2    1 
HETATM 4950 N N3    . Y5P D 2 7   ? 135.649 116.949 120.064 1.00 106.33 ? 9   Y5P O N3    1 
HETATM 4951 C C4    . Y5P D 2 7   ? 134.305 116.698 119.887 1.00 109.34 ? 9   Y5P O C4    1 
HETATM 4952 C C6    . Y5P D 2 7   ? 134.120 117.035 122.245 1.00 108.81 ? 9   Y5P O C6    1 
HETATM 4953 O OP1   . Y5P D 2 7   ? 130.920 116.795 124.978 1.00 132.45 ? 9   Y5P O OP1   1 
HETATM 4954 O OP2   . Y5P D 2 7   ? 132.039 114.532 125.433 1.00 129.87 ? 9   Y5P O OP2   1 
HETATM 4955 C C5    . Y5P D 2 7   ? 133.522 116.756 121.082 1.00 111.12 ? 9   Y5P O C5    1 
HETATM 4956 N N1    . P5P D 2 8   ? 130.738 123.709 134.081 1.00 108.35 ? 10  P5P O N1    1 
HETATM 4957 C C2    . P5P D 2 8   ? 130.941 124.550 133.060 1.00 114.02 ? 10  P5P O C2    1 
HETATM 4958 N N3    . P5P D 2 8   ? 131.741 124.413 132.005 1.00 122.83 ? 10  P5P O N3    1 
HETATM 4959 C C4    . P5P D 2 8   ? 132.398 123.241 132.056 1.00 119.89 ? 10  P5P O C4    1 
HETATM 4960 C C5    . P5P D 2 8   ? 132.294 122.274 133.038 1.00 109.62 ? 10  P5P O C5    1 
HETATM 4961 C C6    . P5P D 2 8   ? 131.413 122.539 134.101 1.00 105.32 ? 10  P5P O C6    1 
HETATM 4962 N N7    . P5P D 2 8   ? 133.122 121.196 132.755 1.00 104.87 ? 10  P5P O N7    1 
HETATM 4963 C C8    . P5P D 2 8   ? 133.696 121.530 131.625 1.00 114.30 ? 10  P5P O C8    1 
HETATM 4964 N N9    . P5P D 2 8   ? 133.303 122.754 131.144 1.00 122.51 ? 10  P5P O N9    1 
HETATM 4965 C "C1'" . P5P D 2 8   ? 133.749 123.430 129.910 1.00 124.00 ? 10  P5P O "C1'" 1 
HETATM 4966 C "C2'" . P5P D 2 8   ? 135.116 124.092 130.075 1.00 123.54 ? 10  P5P O "C2'" 1 
HETATM 4967 O "O2'" . P5P D 2 8   ? 135.172 125.239 129.240 1.00 123.56 ? 10  P5P O "O2'" 1 
HETATM 4968 C "C3'" . P5P D 2 8   ? 136.046 122.998 129.570 1.00 124.09 ? 10  P5P O "C3'" 1 
HETATM 4969 O "O3'" . P5P D 2 8   ? 137.309 123.480 129.140 1.00 124.13 ? 10  P5P O "O3'" 1 
HETATM 4970 C "C4'" . P5P D 2 8   ? 135.241 122.368 128.442 1.00 120.37 ? 10  P5P O "C4'" 1 
HETATM 4971 O "O4'" . P5P D 2 8   ? 133.864 122.463 128.890 1.00 119.34 ? 10  P5P O "O4'" 1 
HETATM 4972 C "C5'" . P5P D 2 8   ? 135.558 120.929 128.124 1.00 121.96 ? 10  P5P O "C5'" 1 
HETATM 4973 O "O5'" . P5P D 2 8   ? 136.924 120.744 127.785 1.00 125.60 ? 10  P5P O "O5'" 1 
HETATM 4974 P P     . P5P D 2 8   ? 137.532 119.280 127.621 1.00 112.57 ? 10  P5P O P     1 
HETATM 4975 O OP1   . P5P D 2 8   ? 139.012 119.388 127.670 1.00 105.94 ? 10  P5P O OP1   1 
HETATM 4976 O OP2   . P5P D 2 8   ? 136.829 118.384 128.573 1.00 108.77 ? 10  P5P O OP2   1 
HETATM 4977 N N1    . P5P D 2 9   ? 142.063 126.481 137.290 1.00 123.25 ? 11  P5P O N1    1 
HETATM 4978 C C2    . P5P D 2 9   ? 142.152 127.579 136.529 1.00 119.89 ? 11  P5P O C2    1 
HETATM 4979 N N3    . P5P D 2 9   ? 141.543 127.857 135.379 1.00 118.54 ? 11  P5P O N3    1 
HETATM 4980 C C4    . P5P D 2 9   ? 140.750 126.840 135.005 1.00 122.18 ? 11  P5P O C4    1 
HETATM 4981 C C5    . P5P D 2 9   ? 140.556 125.649 135.680 1.00 120.30 ? 11  P5P O C5    1 
HETATM 4982 C C6    . P5P D 2 9   ? 141.256 125.476 136.885 1.00 121.44 ? 11  P5P O C6    1 
HETATM 4983 N N7    . P5P D 2 9   ? 139.667 124.835 134.994 1.00 118.91 ? 11  P5P O N7    1 
HETATM 4984 C C8    . P5P D 2 9   ? 139.349 125.539 133.936 1.00 123.27 ? 11  P5P O C8    1 
HETATM 4985 N N9    . P5P D 2 9   ? 139.969 126.762 133.878 1.00 125.71 ? 11  P5P O N9    1 
HETATM 4986 C "C1'" . P5P D 2 9   ? 139.830 127.793 132.833 1.00 127.94 ? 11  P5P O "C1'" 1 
HETATM 4987 C "C2'" . P5P D 2 9   ? 141.118 127.976 132.031 1.00 130.99 ? 11  P5P O "C2'" 1 
HETATM 4988 O "O2'" . P5P D 2 9   ? 141.211 129.331 131.614 1.00 129.93 ? 11  P5P O "O2'" 1 
HETATM 4989 C "C3'" . P5P D 2 9   ? 140.871 127.052 130.847 1.00 130.79 ? 11  P5P O "C3'" 1 
HETATM 4990 O "O3'" . P5P D 2 9   ? 141.652 127.369 129.708 1.00 131.64 ? 11  P5P O "O3'" 1 
HETATM 4991 C "C4'" . P5P D 2 9   ? 139.378 127.214 130.605 1.00 130.31 ? 11  P5P O "C4'" 1 
HETATM 4992 O "O4'" . P5P D 2 9   ? 138.820 127.387 131.934 1.00 127.81 ? 11  P5P O "O4'" 1 
HETATM 4993 C "C5'" . P5P D 2 9   ? 138.693 126.062 129.913 1.00 131.78 ? 11  P5P O "C5'" 1 
HETATM 4994 O "O5'" . P5P D 2 9   ? 138.626 124.916 130.748 1.00 131.07 ? 11  P5P O "O5'" 1 
HETATM 4995 P P     . P5P D 2 9   ? 138.579 123.450 130.126 1.00 130.81 ? 11  P5P O P     1 
HETATM 4996 O OP1   . P5P D 2 9   ? 139.792 123.275 129.290 1.00 123.20 ? 11  P5P O OP1   1 
HETATM 4997 O OP2   . P5P D 2 9   ? 138.303 122.497 131.230 1.00 126.37 ? 11  P5P O OP2   1 
HETATM 4998 P P     . Y5P D 2 10  ? 142.865 126.412 129.265 1.00 133.25 ? 12  Y5P O P     1 
HETATM 4999 C "C5'" . Y5P D 2 10  ? 144.489 127.938 130.648 1.00 131.66 ? 12  Y5P O "C5'" 1 
HETATM 5000 O "O5'" . Y5P D 2 10  ? 143.971 126.642 130.388 1.00 129.09 ? 12  Y5P O "O5'" 1 
HETATM 5001 C "C4'" . Y5P D 2 10  ? 145.310 127.958 131.913 1.00 136.41 ? 12  Y5P O "C4'" 1 
HETATM 5002 O "O4'" . Y5P D 2 10  ? 144.470 127.605 133.045 1.00 137.99 ? 12  Y5P O "O4'" 1 
HETATM 5003 C "C3'" . Y5P D 2 10  ? 146.457 126.960 131.975 1.00 136.04 ? 12  Y5P O "C3'" 1 
HETATM 5004 O "O3'" . Y5P D 2 10  ? 147.621 127.412 131.305 1.00 133.93 ? 12  Y5P O "O3'" 1 
HETATM 5005 C "C2'" . Y5P D 2 10  ? 146.650 126.765 133.472 1.00 135.53 ? 12  Y5P O "C2'" 1 
HETATM 5006 O "O2'" . Y5P D 2 10  ? 147.398 127.831 134.038 1.00 132.95 ? 12  Y5P O "O2'" 1 
HETATM 5007 C "C1'" . Y5P D 2 10  ? 145.209 126.844 133.977 1.00 135.10 ? 12  Y5P O "C1'" 1 
HETATM 5008 N N1    . Y5P D 2 10  ? 144.585 125.506 134.089 1.00 134.07 ? 12  Y5P O N1    1 
HETATM 5009 C C2    . Y5P D 2 10  ? 144.893 124.744 135.197 1.00 131.72 ? 12  Y5P O C2    1 
HETATM 5010 N N3    . Y5P D 2 10  ? 144.283 123.515 135.238 1.00 131.37 ? 12  Y5P O N3    1 
HETATM 5011 C C4    . Y5P D 2 10  ? 143.416 122.985 134.305 1.00 130.35 ? 12  Y5P O C4    1 
HETATM 5012 C C6    . Y5P D 2 10  ? 143.728 125.037 133.122 1.00 131.67 ? 12  Y5P O C6    1 
HETATM 5013 O OP1   . Y5P D 2 10  ? 143.401 126.922 127.978 1.00 128.67 ? 12  Y5P O OP1   1 
HETATM 5014 O OP2   . Y5P D 2 10  ? 142.401 125.005 129.365 1.00 132.78 ? 12  Y5P O OP2   1 
HETATM 5015 C C5    . Y5P D 2 10  ? 143.146 123.835 133.186 1.00 130.12 ? 12  Y5P O C5    1 
HETATM 5016 P P     . Y5P E 3 1   ? 128.869 167.680 134.422 1.00 175.28 ? 10  Y5P N P     1 
HETATM 5017 C "C5'" . Y5P E 3 1   ? 126.627 166.423 133.891 1.00 175.74 ? 10  Y5P N "C5'" 1 
HETATM 5018 O "O5'" . Y5P E 3 1   ? 127.279 167.585 134.386 1.00 178.24 ? 10  Y5P N "O5'" 1 
HETATM 5019 C "C4'" . Y5P E 3 1   ? 125.418 166.780 133.064 1.00 180.03 ? 10  Y5P N "C4'" 1 
HETATM 5020 O "O4'" . Y5P E 3 1   ? 124.822 165.576 132.519 1.00 179.12 ? 10  Y5P N "O4'" 1 
HETATM 5021 C "C3'" . Y5P E 3 1   ? 124.276 167.456 133.807 1.00 183.35 ? 10  Y5P N "C3'" 1 
HETATM 5022 O "O3'" . Y5P E 3 1   ? 124.487 168.846 133.988 1.00 186.53 ? 10  Y5P N "O3'" 1 
HETATM 5023 C "C2'" . Y5P E 3 1   ? 123.070 167.131 132.935 1.00 183.23 ? 10  Y5P N "C2'" 1 
HETATM 5024 O "O2'" . Y5P E 3 1   ? 122.989 168.010 131.823 1.00 182.01 ? 10  Y5P N "O2'" 1 
HETATM 5025 C "C1'" . Y5P E 3 1   ? 123.421 165.730 132.430 1.00 180.32 ? 10  Y5P N "C1'" 1 
HETATM 5026 N N1    . Y5P E 3 1   ? 122.768 164.652 133.210 1.00 177.66 ? 10  Y5P N N1    1 
HETATM 5027 C C2    . Y5P E 3 1   ? 121.419 164.445 133.006 1.00 174.22 ? 10  Y5P N C2    1 
HETATM 5028 N N3    . Y5P E 3 1   ? 120.864 163.427 133.741 1.00 172.16 ? 10  Y5P N N3    1 
HETATM 5029 C C4    . Y5P E 3 1   ? 121.519 162.602 134.634 1.00 169.18 ? 10  Y5P N C4    1 
HETATM 5030 C C6    . Y5P E 3 1   ? 123.478 163.859 134.082 1.00 170.98 ? 10  Y5P N C6    1 
HETATM 5031 O OP1   . Y5P E 3 1   ? 129.338 168.008 133.052 1.00 176.72 ? 10  Y5P N OP1   1 
HETATM 5032 O OP2   . Y5P E 3 1   ? 129.252 168.557 135.557 1.00 170.11 ? 10  Y5P N OP2   1 
HETATM 5033 C C5    . Y5P E 3 1   ? 122.917 162.869 134.785 1.00 167.65 ? 10  Y5P N C5    1 
HETATM 5034 P P     . Y5P E 3 2   ? 123.973 169.583 135.321 1.00 187.44 ? 11  Y5P N P     1 
HETATM 5035 C "C5'" . Y5P E 3 2   ? 122.057 170.777 133.989 1.00 184.19 ? 11  Y5P N "C5'" 1 
HETATM 5036 O "O5'" . Y5P E 3 2   ? 122.437 169.888 135.029 1.00 185.95 ? 11  Y5P N "O5'" 1 
HETATM 5037 C "C4'" . Y5P E 3 2   ? 120.594 170.643 133.652 1.00 185.16 ? 11  Y5P N "C4'" 1 
HETATM 5038 O "O4'" . Y5P E 3 2   ? 120.300 169.266 133.297 1.00 183.83 ? 11  Y5P N "O4'" 1 
HETATM 5039 C "C3'" . Y5P E 3 2   ? 119.617 170.949 134.777 1.00 188.97 ? 11  Y5P N "C3'" 1 
HETATM 5040 O "O3'" . Y5P E 3 2   ? 119.381 172.336 134.950 1.00 192.06 ? 11  Y5P N "O3'" 1 
HETATM 5041 C "C2'" . Y5P E 3 2   ? 118.380 170.166 134.362 1.00 188.01 ? 11  Y5P N "C2'" 1 
HETATM 5042 O "O2'" . Y5P E 3 2   ? 117.648 170.853 133.358 1.00 186.76 ? 11  Y5P N "O2'" 1 
HETATM 5043 C "C1'" . Y5P E 3 2   ? 119.007 168.918 133.746 1.00 184.54 ? 11  Y5P N "C1'" 1 
HETATM 5044 N N1    . Y5P E 3 2   ? 119.127 167.813 134.722 1.00 182.13 ? 11  Y5P N N1    1 
HETATM 5045 C C2    . Y5P E 3 2   ? 117.988 167.096 135.025 1.00 181.38 ? 11  Y5P N C2    1 
HETATM 5046 N N3    . Y5P E 3 2   ? 118.165 166.080 135.931 1.00 181.50 ? 11  Y5P N N3    1 
HETATM 5047 C C4    . Y5P E 3 2   ? 119.347 165.721 136.549 1.00 181.51 ? 11  Y5P N C4    1 
HETATM 5048 C C6    . Y5P E 3 2   ? 120.333 167.506 135.302 1.00 181.80 ? 11  Y5P N C6    1 
HETATM 5049 O OP1   . Y5P E 3 2   ? 124.682 170.883 135.421 1.00 184.22 ? 11  Y5P N OP1   1 
HETATM 5050 O OP2   . Y5P E 3 2   ? 124.050 168.621 136.449 1.00 182.05 ? 11  Y5P N OP2   1 
HETATM 5051 C C5    . Y5P E 3 2   ? 120.483 166.511 136.182 1.00 181.04 ? 11  Y5P N C5    1 
HETATM 5052 P P     . Y5P E 3 3   ? 118.689 172.875 136.297 1.00 194.71 ? 12  Y5P N P     1 
HETATM 5053 C "C5'" . Y5P E 3 3   ? 116.213 172.687 135.459 1.00 192.07 ? 12  Y5P N "C5'" 1 
HETATM 5054 O "O5'" . Y5P E 3 3   ? 117.249 172.192 136.294 1.00 196.06 ? 12  Y5P N "O5'" 1 
HETATM 5055 C "C4'" . Y5P E 3 3   ? 114.902 171.985 135.711 1.00 192.93 ? 12  Y5P N "C4'" 1 
HETATM 5056 O "O4'" . Y5P E 3 3   ? 115.037 170.561 135.456 1.00 191.56 ? 12  Y5P N "O4'" 1 
HETATM 5057 C "C3'" . Y5P E 3 3   ? 114.367 172.047 137.132 1.00 195.04 ? 12  Y5P N "C3'" 1 
HETATM 5058 O "O3'" . Y5P E 3 3   ? 113.746 173.280 137.449 1.00 197.71 ? 12  Y5P N "O3'" 1 
HETATM 5059 C "C2'" . Y5P E 3 3   ? 113.421 170.856 137.171 1.00 193.64 ? 12  Y5P N "C2'" 1 
HETATM 5060 O "O2'" . Y5P E 3 3   ? 112.190 171.155 136.529 1.00 193.34 ? 12  Y5P N "O2'" 1 
HETATM 5061 C "C1'" . Y5P E 3 3   ? 114.190 169.838 136.329 1.00 191.60 ? 12  Y5P N "C1'" 1 
HETATM 5062 N N1    . Y5P E 3 3   ? 115.017 168.946 137.173 1.00 189.67 ? 12  Y5P N N1    1 
HETATM 5063 C C2    . Y5P E 3 3   ? 114.385 167.907 137.860 1.00 189.53 ? 12  Y5P N C2    1 
HETATM 5064 N N3    . Y5P E 3 3   ? 115.122 167.081 138.639 1.00 188.57 ? 12  Y5P N N3    1 
HETATM 5065 C C4    . Y5P E 3 3   ? 116.438 167.271 138.746 1.00 186.21 ? 12  Y5P N C4    1 
HETATM 5066 C C6    . Y5P E 3 3   ? 116.363 169.132 137.291 1.00 188.36 ? 12  Y5P N C6    1 
HETATM 5067 O OP1   . Y5P E 3 3   ? 118.496 174.340 136.148 1.00 190.41 ? 12  Y5P N OP1   1 
HETATM 5068 O OP2   . Y5P E 3 3   ? 119.449 172.352 137.461 1.00 184.98 ? 12  Y5P N OP2   1 
HETATM 5069 C C5    . Y5P E 3 3   ? 117.105 168.325 138.058 1.00 186.09 ? 12  Y5P N C5    1 
HETATM 5070 P P     . Y5P E 3 4   ? 113.731 173.799 138.970 1.00 196.19 ? 13  Y5P N P     1 
HETATM 5071 C "C5'" . Y5P E 3 4   ? 111.325 172.824 139.320 1.00 197.79 ? 13  Y5P N "C5'" 1 
HETATM 5072 O "O5'" . Y5P E 3 4   ? 112.694 172.831 139.696 1.00 198.00 ? 13  Y5P N "O5'" 1 
HETATM 5073 C "C4'" . Y5P E 3 4   ? 110.537 171.790 140.085 1.00 199.31 ? 13  Y5P N "C4'" 1 
HETATM 5074 O "O4'" . Y5P E 3 4   ? 110.985 170.456 139.725 1.00 198.06 ? 13  Y5P N "O4'" 1 
HETATM 5075 C "C3'" . Y5P E 3 4   ? 110.671 171.821 141.599 1.00 202.86 ? 13  Y5P N "C3'" 1 
HETATM 5076 O "O3'" . Y5P E 3 4   ? 109.885 172.825 142.215 1.00 204.96 ? 13  Y5P N "O3'" 1 
HETATM 5077 C "C2'" . Y5P E 3 4   ? 110.267 170.406 141.989 1.00 201.89 ? 13  Y5P N "C2'" 1 
HETATM 5078 O "O2'" . Y5P E 3 4   ? 108.856 170.252 141.973 1.00 199.18 ? 13  Y5P N "O2'" 1 
HETATM 5079 C "C1'" . Y5P E 3 4   ? 110.867 169.595 140.840 1.00 199.33 ? 13  Y5P N "C1'" 1 
HETATM 5080 N N1    . Y5P E 3 4   ? 112.205 169.059 141.181 1.00 198.23 ? 13  Y5P N N1    1 
HETATM 5081 C C2    . Y5P E 3 4   ? 112.251 167.987 142.049 1.00 195.06 ? 13  Y5P N C2    1 
HETATM 5082 N N3    . Y5P E 3 4   ? 113.510 167.526 142.339 1.00 191.98 ? 13  Y5P N N3    1 
HETATM 5083 C C4    . Y5P E 3 4   ? 114.704 168.021 141.856 1.00 190.60 ? 13  Y5P N C4    1 
HETATM 5084 C C6    . Y5P E 3 4   ? 113.360 169.599 140.666 1.00 196.02 ? 13  Y5P N C6    1 
HETATM 5085 O OP1   . Y5P E 3 4   ? 113.166 175.172 138.982 1.00 196.76 ? 13  Y5P N OP1   1 
HETATM 5086 O OP2   . Y5P E 3 4   ? 115.074 173.555 139.555 1.00 188.75 ? 13  Y5P N OP2   1 
HETATM 5087 C C5    . Y5P E 3 4   ? 114.577 169.132 140.963 1.00 191.66 ? 13  Y5P N C5    1 
HETATM 5088 P P     . Y5P E 3 5   ? 110.332 173.438 143.633 1.00 207.98 ? 14  Y5P N P     1 
HETATM 5089 C "C5'" . Y5P E 3 5   ? 108.854 171.888 145.144 1.00 205.84 ? 14  Y5P N "C5'" 1 
HETATM 5090 O "O5'" . Y5P E 3 5   ? 110.143 172.230 144.656 1.00 204.10 ? 14  Y5P N "O5'" 1 
HETATM 5091 C "C4'" . Y5P E 3 5   ? 108.886 170.644 145.997 1.00 206.46 ? 14  Y5P N "C4'" 1 
HETATM 5092 O "O4'" . Y5P E 3 5   ? 109.573 169.577 145.293 1.00 203.88 ? 14  Y5P N "O4'" 1 
HETATM 5093 C "C3'" . Y5P E 3 5   ? 109.631 170.750 147.318 1.00 207.99 ? 14  Y5P N "C3'" 1 
HETATM 5094 O "O3'" . Y5P E 3 5   ? 108.867 171.373 148.336 1.00 210.54 ? 14  Y5P N "O3'" 1 
HETATM 5095 C "C2'" . Y5P E 3 5   ? 109.977 169.298 147.620 1.00 205.76 ? 14  Y5P N "C2'" 1 
HETATM 5096 O "O2'" . Y5P E 3 5   ? 108.866 168.607 148.172 1.00 204.80 ? 14  Y5P N "O2'" 1 
HETATM 5097 C "C1'" . Y5P E 3 5   ? 110.250 168.750 146.218 1.00 202.94 ? 14  Y5P N "C1'" 1 
HETATM 5098 N N1    . Y5P E 3 5   ? 111.693 168.733 145.886 1.00 201.49 ? 14  Y5P N N1    1 
HETATM 5099 C C2    . Y5P E 3 5   ? 112.502 167.761 146.482 1.00 201.62 ? 14  Y5P N C2    1 
HETATM 5100 N N3    . Y5P E 3 5   ? 113.823 167.723 146.184 1.00 201.77 ? 14  Y5P N N3    1 
HETATM 5101 C C4    . Y5P E 3 5   ? 114.336 168.607 145.325 1.00 200.42 ? 14  Y5P N C4    1 
HETATM 5102 C C6    . Y5P E 3 5   ? 112.229 169.629 145.005 1.00 199.78 ? 14  Y5P N C6    1 
HETATM 5103 O OP1   . Y5P E 3 5   ? 109.355 174.497 143.993 1.00 209.62 ? 14  Y5P N OP1   1 
HETATM 5104 O OP2   . Y5P E 3 5   ? 111.779 173.765 143.567 1.00 200.46 ? 14  Y5P N OP2   1 
HETATM 5105 C C5    . Y5P E 3 5   ? 113.532 169.604 144.700 1.00 199.05 ? 14  Y5P N C5    1 
HETATM 5106 N N1    . P5P E 3 6   ? 116.908 167.474 150.198 1.00 203.15 ? 15  P5P N N1    1 
HETATM 5107 C C2    . P5P E 3 6   ? 116.178 166.818 151.109 1.00 202.71 ? 15  P5P N C2    1 
HETATM 5108 N N3    . P5P E 3 6   ? 114.896 166.981 151.437 1.00 203.28 ? 15  P5P N N3    1 
HETATM 5109 C C4    . P5P E 3 6   ? 114.336 167.962 150.706 1.00 205.27 ? 15  P5P N C4    1 
HETATM 5110 C C5    . P5P E 3 6   ? 114.959 168.724 149.735 1.00 203.68 ? 15  P5P N C5    1 
HETATM 5111 C C6    . P5P E 3 6   ? 116.314 168.453 149.482 1.00 202.19 ? 15  P5P N C6    1 
HETATM 5112 N N7    . P5P E 3 6   ? 114.076 169.642 149.187 1.00 204.56 ? 15  P5P N N7    1 
HETATM 5113 C C8    . P5P E 3 6   ? 112.956 169.420 149.828 1.00 207.30 ? 15  P5P N C8    1 
HETATM 5114 N N9    . P5P E 3 6   ? 113.038 168.416 150.759 1.00 208.55 ? 15  P5P N N9    1 
HETATM 5115 C "C1'" . P5P E 3 6   ? 111.961 167.932 151.641 1.00 211.89 ? 15  P5P N "C1'" 1 
HETATM 5116 C "C2'" . P5P E 3 6   ? 112.073 168.516 153.050 1.00 210.47 ? 15  P5P N "C2'" 1 
HETATM 5117 O "O2'" . P5P E 3 6   ? 111.574 167.572 153.986 1.00 209.68 ? 15  P5P N "O2'" 1 
HETATM 5118 C "C3'" . P5P E 3 6   ? 111.157 169.729 152.948 1.00 212.25 ? 15  P5P N "C3'" 1 
HETATM 5119 O "O3'" . P5P E 3 6   ? 110.682 170.190 154.200 1.00 211.77 ? 15  P5P N "O3'" 1 
HETATM 5120 C "C4'" . P5P E 3 6   ? 110.045 169.231 152.037 1.00 213.56 ? 15  P5P N "C4'" 1 
HETATM 5121 O "O4'" . P5P E 3 6   ? 110.722 168.346 151.104 1.00 214.38 ? 15  P5P N "O4'" 1 
HETATM 5122 C "C5'" . P5P E 3 6   ? 109.291 170.293 151.278 1.00 212.29 ? 15  P5P N "C5'" 1 
HETATM 5123 O "O5'" . P5P E 3 6   ? 110.164 171.082 150.481 1.00 212.07 ? 15  P5P N "O5'" 1 
HETATM 5124 P P     . P5P E 3 6   ? 109.595 172.204 149.504 1.00 209.05 ? 15  P5P N P     1 
HETATM 5125 O OP1   . P5P E 3 6   ? 108.557 172.970 150.240 1.00 207.35 ? 15  P5P N OP1   1 
HETATM 5126 O OP2   . P5P E 3 6   ? 110.751 172.924 148.911 1.00 206.04 ? 15  P5P N OP2   1 
HETATM 5127 P P     . Y5P E 3 7   ? 125.615 164.695 147.701 1.00 218.90 ? 28  Y5P N P     1 
HETATM 5128 C "C5'" . Y5P E 3 7   ? 124.986 163.474 149.936 1.00 218.56 ? 28  Y5P N "C5'" 1 
HETATM 5129 O "O5'" . Y5P E 3 7   ? 124.589 164.304 148.855 1.00 218.34 ? 28  Y5P N "O5'" 1 
HETATM 5130 C "C4'" . Y5P E 3 7   ? 123.845 163.231 150.891 1.00 218.24 ? 28  Y5P N "C4'" 1 
HETATM 5131 O "O4'" . Y5P E 3 7   ? 123.437 164.489 151.495 1.00 216.41 ? 28  Y5P N "O4'" 1 
HETATM 5132 C "C3'" . Y5P E 3 7   ? 122.567 162.684 150.272 1.00 216.70 ? 28  Y5P N "C3'" 1 
HETATM 5133 O "O3'" . Y5P E 3 7   ? 122.602 161.282 150.073 1.00 217.50 ? 28  Y5P N "O3'" 1 
HETATM 5134 C "C2'" . Y5P E 3 7   ? 121.501 163.138 151.259 1.00 213.55 ? 28  Y5P N "C2'" 1 
HETATM 5135 O "O2'" . Y5P E 3 7   ? 121.474 162.301 152.405 1.00 209.48 ? 28  Y5P N "O2'" 1 
HETATM 5136 C "C1'" . Y5P E 3 7   ? 122.034 164.511 151.663 1.00 214.28 ? 28  Y5P N "C1'" 1 
HETATM 5137 N N1    . Y5P E 3 7   ? 121.483 165.600 150.823 1.00 213.94 ? 28  Y5P N N1    1 
HETATM 5138 C C2    . Y5P E 3 7   ? 120.138 165.903 150.931 1.00 210.61 ? 28  Y5P N C2    1 
HETATM 5139 N N3    . Y5P E 3 7   ? 119.706 166.927 150.123 1.00 207.98 ? 28  Y5P N N3    1 
HETATM 5140 C C4    . Y5P E 3 7   ? 120.474 167.665 149.242 1.00 207.02 ? 28  Y5P N C4    1 
HETATM 5141 C C6    . Y5P E 3 7   ? 122.298 166.302 149.966 1.00 213.25 ? 28  Y5P N C6    1 
HETATM 5142 O OP1   . Y5P E 3 7   ? 126.210 163.442 147.169 1.00 216.64 ? 28  Y5P N OP1   1 
HETATM 5143 O OP2   . Y5P E 3 7   ? 124.921 165.628 146.778 1.00 219.71 ? 28  Y5P N OP2   1 
HETATM 5144 C C5    . Y5P E 3 7   ? 121.855 167.296 149.192 1.00 210.24 ? 28  Y5P N C5    1 
HETATM 5145 N N1    . P5P E 3 8   ? 115.443 165.942 147.777 1.00 204.27 ? 29  P5P N N1    1 
HETATM 5146 C C2    . P5P E 3 8   ? 114.831 165.135 148.704 1.00 201.98 ? 29  P5P N C2    1 
HETATM 5147 N N3    . P5P E 3 8   ? 115.446 164.164 149.362 1.00 200.97 ? 29  P5P N N3    1 
HETATM 5148 C C4    . P5P E 3 8   ? 116.745 164.060 149.013 1.00 202.68 ? 29  P5P N C4    1 
HETATM 5149 C C5    . P5P E 3 8   ? 117.450 164.815 148.099 1.00 203.78 ? 29  P5P N C5    1 
HETATM 5150 C C6    . P5P E 3 8   ? 116.780 165.850 147.399 1.00 203.63 ? 29  P5P N C6    1 
HETATM 5151 N N7    . P5P E 3 8   ? 118.768 164.393 148.021 1.00 204.11 ? 29  P5P N N7    1 
HETATM 5152 C C8    . P5P E 3 8   ? 118.840 163.409 148.873 1.00 205.53 ? 29  P5P N C8    1 
HETATM 5153 N N9    . P5P E 3 8   ? 117.651 163.152 149.510 1.00 204.20 ? 29  P5P N N9    1 
HETATM 5154 C "C1'" . P5P E 3 8   ? 117.400 162.111 150.524 1.00 203.98 ? 29  P5P N "C1'" 1 
HETATM 5155 C "C2'" . P5P E 3 8   ? 116.431 161.046 150.019 1.00 199.26 ? 29  P5P N "C2'" 1 
HETATM 5156 O "O2'" . P5P E 3 8   ? 115.721 160.505 151.124 1.00 196.82 ? 29  P5P N "O2'" 1 
HETATM 5157 C "C3'" . P5P E 3 8   ? 117.395 160.026 149.434 1.00 201.83 ? 29  P5P N "C3'" 1 
HETATM 5158 O "O3'" . P5P E 3 8   ? 116.834 158.732 149.280 1.00 200.44 ? 29  P5P N "O3'" 1 
HETATM 5159 C "C4'" . P5P E 3 8   ? 118.551 160.069 150.423 1.00 204.59 ? 29  P5P N "C4'" 1 
HETATM 5160 O "O4'" . P5P E 3 8   ? 118.622 161.466 150.817 1.00 207.07 ? 29  P5P N "O4'" 1 
HETATM 5161 C "C5'" . P5P E 3 8   ? 119.893 159.625 149.897 1.00 206.28 ? 29  P5P N "C5'" 1 
HETATM 5162 O "O5'" . P5P E 3 8   ? 120.437 160.571 148.990 1.00 209.75 ? 29  P5P N "O5'" 1 
HETATM 5163 P P     . P5P E 3 8   ? 122.007 160.637 148.725 1.00 215.57 ? 29  P5P N P     1 
HETATM 5164 O OP1   . P5P E 3 8   ? 122.514 159.245 148.631 1.00 211.10 ? 29  P5P N OP1   1 
HETATM 5165 O OP2   . P5P E 3 8   ? 122.248 161.579 147.603 1.00 212.85 ? 29  P5P N OP2   1 
HETATM 5166 N N1    . P5P E 3 9   ? 113.592 165.339 144.094 1.00 192.07 ? 30  P5P N N1    1 
HETATM 5167 C C2    . P5P E 3 9   ? 112.421 164.749 144.367 1.00 190.75 ? 30  P5P N C2    1 
HETATM 5168 N N3    . P5P E 3 9   ? 112.164 163.725 145.176 1.00 190.18 ? 30  P5P N N3    1 
HETATM 5169 C C4    . P5P E 3 9   ? 113.294 163.288 145.758 1.00 192.08 ? 30  P5P N C4    1 
HETATM 5170 C C5    . P5P E 3 9   ? 114.569 163.794 145.577 1.00 193.65 ? 30  P5P N C5    1 
HETATM 5171 C C6    . P5P E 3 9   ? 114.708 164.876 144.695 1.00 192.73 ? 30  P5P N C6    1 
HETATM 5172 N N7    . P5P E 3 9   ? 115.490 163.093 146.340 1.00 195.99 ? 30  P5P N N7    1 
HETATM 5173 C C8    . P5P E 3 9   ? 114.763 162.194 146.956 1.00 195.84 ? 30  P5P N C8    1 
HETATM 5174 N N9    . P5P E 3 9   ? 113.427 162.254 146.654 1.00 194.02 ? 30  P5P N N9    1 
HETATM 5175 C "C1'" . P5P E 3 9   ? 112.349 161.392 147.173 1.00 190.12 ? 30  P5P N "C1'" 1 
HETATM 5176 C "C2'" . P5P E 3 9   ? 111.944 160.317 146.167 1.00 186.78 ? 30  P5P N "C2'" 1 
HETATM 5177 O "O2'" . P5P E 3 9   ? 110.568 160.012 146.349 1.00 176.23 ? 30  P5P N "O2'" 1 
HETATM 5178 C "C3'" . P5P E 3 9   ? 112.826 159.155 146.599 1.00 187.67 ? 30  P5P N "C3'" 1 
HETATM 5179 O "O3'" . P5P E 3 9   ? 112.355 157.894 146.157 1.00 188.05 ? 30  P5P N "O3'" 1 
HETATM 5180 C "C4'" . P5P E 3 9   ? 112.836 159.297 148.114 1.00 187.50 ? 30  P5P N "C4'" 1 
HETATM 5181 O "O4'" . P5P E 3 9   ? 112.819 160.734 148.332 1.00 191.11 ? 30  P5P N "O4'" 1 
HETATM 5182 C "C5'" . P5P E 3 9   ? 114.012 158.692 148.840 1.00 189.51 ? 30  P5P N "C5'" 1 
HETATM 5183 O "O5'" . P5P E 3 9   ? 114.825 157.910 147.977 1.00 189.56 ? 30  P5P N "O5'" 1 
HETATM 5184 P P     . P5P E 3 9   ? 116.383 158.208 147.826 1.00 197.59 ? 30  P5P N P     1 
HETATM 5185 O OP1   . P5P E 3 9   ? 117.074 156.916 147.583 1.00 180.12 ? 30  P5P N OP1   1 
HETATM 5186 O OP2   . P5P E 3 9   ? 116.535 159.315 146.847 1.00 193.30 ? 30  P5P N OP2   1 
HETATM 5187 N N1    . P5P E 3 10  ? 113.671 165.118 140.196 1.00 187.32 ? 31  P5P N N1    1 
HETATM 5188 C C2    . P5P E 3 10  ? 112.319 164.980 140.002 1.00 184.88 ? 31  P5P N C2    1 
HETATM 5189 N N3    . P5P E 3 10  ? 111.577 164.054 140.589 1.00 184.67 ? 31  P5P N N3    1 
HETATM 5190 C C4    . P5P E 3 10  ? 112.303 163.259 141.403 1.00 185.78 ? 31  P5P N C4    1 
HETATM 5191 C C5    . P5P E 3 10  ? 113.655 163.313 141.666 1.00 187.58 ? 31  P5P N C5    1 
HETATM 5192 C C6    . P5P E 3 10  ? 114.439 164.308 141.027 1.00 188.59 ? 31  P5P N C6    1 
HETATM 5193 N N7    . P5P E 3 10  ? 114.021 162.316 142.560 1.00 184.88 ? 31  P5P N N7    1 
HETATM 5194 C C8    . P5P E 3 10  ? 112.907 161.688 142.819 1.00 183.19 ? 31  P5P N C8    1 
HETATM 5195 N N9    . P5P E 3 10  ? 111.825 162.203 142.147 1.00 183.73 ? 31  P5P N N9    1 
HETATM 5196 C "C1'" . P5P E 3 10  ? 110.423 161.744 142.222 1.00 178.96 ? 31  P5P N "C1'" 1 
HETATM 5197 C "C2'" . P5P E 3 10  ? 109.970 161.001 140.964 1.00 175.80 ? 31  P5P N "C2'" 1 
HETATM 5198 O "O2'" . P5P E 3 10  ? 108.618 161.340 140.691 1.00 174.71 ? 31  P5P N "O2'" 1 
HETATM 5199 C "C3'" . P5P E 3 10  ? 110.101 159.544 141.394 1.00 176.00 ? 31  P5P N "C3'" 1 
HETATM 5200 O "O3'" . P5P E 3 10  ? 109.263 158.661 140.668 1.00 174.56 ? 31  P5P N "O3'" 1 
HETATM 5201 C "C4'" . P5P E 3 10  ? 109.752 159.593 142.873 1.00 173.55 ? 31  P5P N "C4'" 1 
HETATM 5202 O "O4'" . P5P E 3 10  ? 110.284 160.866 143.320 1.00 178.00 ? 31  P5P N "O4'" 1 
HETATM 5203 C "C5'" . P5P E 3 10  ? 110.309 158.476 143.721 1.00 173.03 ? 31  P5P N "C5'" 1 
HETATM 5204 O "O5'" . P5P E 3 10  ? 111.726 158.536 143.798 1.00 176.43 ? 31  P5P N "O5'" 1 
HETATM 5205 P P     . P5P E 3 10  ? 112.550 157.451 144.624 1.00 179.75 ? 31  P5P N P     1 
HETATM 5206 O OP1   . P5P E 3 10  ? 111.891 156.134 144.436 1.00 161.68 ? 31  P5P N OP1   1 
HETATM 5207 O OP2   . P5P E 3 10  ? 113.986 157.608 144.281 1.00 180.29 ? 31  P5P N OP2   1 
HETATM 5208 N N1    . P5P E 3 11  ? 115.795 164.847 136.829 1.00 179.66 ? 32  P5P N N1    1 
HETATM 5209 C C2    . P5P E 3 11  ? 114.666 165.217 136.212 1.00 178.45 ? 32  P5P N C2    1 
HETATM 5210 N N3    . P5P E 3 11  ? 113.449 164.682 136.282 1.00 177.58 ? 32  P5P N N3    1 
HETATM 5211 C C4    . P5P E 3 11  ? 113.446 163.623 137.109 1.00 177.79 ? 32  P5P N C4    1 
HETATM 5212 C C5    . P5P E 3 11  ? 114.525 163.118 137.811 1.00 178.92 ? 32  P5P N C5    1 
HETATM 5213 C C6    . P5P E 3 11  ? 115.756 163.778 137.652 1.00 180.51 ? 32  P5P N C6    1 
HETATM 5214 N N7    . P5P E 3 11  ? 114.149 162.014 138.562 1.00 176.31 ? 32  P5P N N7    1 
HETATM 5215 C C8    . P5P E 3 11  ? 112.873 161.878 138.301 1.00 175.54 ? 32  P5P N C8    1 
HETATM 5216 N N9    . P5P E 3 11  ? 112.383 162.813 137.424 1.00 175.24 ? 32  P5P N N9    1 
HETATM 5217 C "C1'" . P5P E 3 11  ? 110.995 162.940 136.939 1.00 174.50 ? 32  P5P N "C1'" 1 
HETATM 5218 C "C2'" . P5P E 3 11  ? 110.888 162.816 135.419 1.00 172.95 ? 32  P5P N "C2'" 1 
HETATM 5219 O "O2'" . P5P E 3 11  ? 109.823 163.638 134.964 1.00 172.06 ? 32  P5P N "O2'" 1 
HETATM 5220 C "C3'" . P5P E 3 11  ? 110.557 161.339 135.254 1.00 173.76 ? 32  P5P N "C3'" 1 
HETATM 5221 O "O3'" . P5P E 3 11  ? 109.910 161.034 134.029 1.00 177.82 ? 32  P5P N "O3'" 1 
HETATM 5222 C "C4'" . P5P E 3 11  ? 109.682 161.054 136.467 1.00 170.66 ? 32  P5P N "C4'" 1 
HETATM 5223 O "O4'" . P5P E 3 11  ? 110.228 161.902 137.510 1.00 171.86 ? 32  P5P N "O4'" 1 
HETATM 5224 C "C5'" . P5P E 3 11  ? 109.657 159.621 136.937 1.00 162.68 ? 32  P5P N "C5'" 1 
HETATM 5225 O "O5'" . P5P E 3 11  ? 109.273 159.528 138.301 1.00 163.50 ? 32  P5P N "O5'" 1 
HETATM 5226 P P     . P5P E 3 11  ? 109.635 158.239 139.164 1.00 167.91 ? 32  P5P N P     1 
HETATM 5227 O OP1   . P5P E 3 11  ? 108.713 157.148 138.758 1.00 151.92 ? 32  P5P N OP1   1 
HETATM 5228 O OP2   . P5P E 3 11  ? 111.103 158.027 139.091 1.00 162.33 ? 32  P5P N OP2   1 
HETATM 5229 N N1    . P5P E 3 12  ? 118.074 163.612 134.040 1.00 169.84 ? 33  P5P N N1    1 
HETATM 5230 C C2    . P5P E 3 12  ? 117.497 164.492 133.213 1.00 172.02 ? 33  P5P N C2    1 
HETATM 5231 N N3    . P5P E 3 12  ? 116.248 164.537 132.762 1.00 172.64 ? 33  P5P N N3    1 
HETATM 5232 C C4    . P5P E 3 12  ? 115.533 163.517 133.259 1.00 172.38 ? 33  P5P N C4    1 
HETATM 5233 C C5    . P5P E 3 12  ? 115.979 162.531 134.120 1.00 169.44 ? 33  P5P N C5    1 
HETATM 5234 C C6    . P5P E 3 12  ? 117.323 162.599 134.524 1.00 168.06 ? 33  P5P N C6    1 
HETATM 5235 N N7    . P5P E 3 12  ? 114.957 161.641 134.416 1.00 169.55 ? 33  P5P N N7    1 
HETATM 5236 C C8    . P5P E 3 12  ? 113.934 162.103 133.738 1.00 171.86 ? 33  P5P N C8    1 
HETATM 5237 N N9    . P5P E 3 12  ? 114.213 163.235 133.012 1.00 174.27 ? 33  P5P N N9    1 
HETATM 5238 C "C1'" . P5P E 3 12  ? 113.302 164.016 132.153 1.00 175.33 ? 33  P5P N "C1'" 1 
HETATM 5239 C "C2'" . P5P E 3 12  ? 113.688 163.953 130.674 1.00 173.86 ? 33  P5P N "C2'" 1 
HETATM 5240 O "O2'" . P5P E 3 12  ? 113.354 165.189 130.057 1.00 171.13 ? 33  P5P N "O2'" 1 
HETATM 5241 C "C3'" . P5P E 3 12  ? 112.794 162.825 130.174 1.00 175.93 ? 33  P5P N "C3'" 1 
HETATM 5242 O "O3'" . P5P E 3 12  ? 112.549 162.853 128.778 1.00 172.11 ? 33  P5P N "O3'" 1 
HETATM 5243 C "C4'" . P5P E 3 12  ? 111.525 163.018 130.991 1.00 176.52 ? 33  P5P N "C4'" 1 
HETATM 5244 O "O4'" . P5P E 3 12  ? 112.000 163.486 132.280 1.00 177.14 ? 33  P5P N "O4'" 1 
HETATM 5245 C "C5'" . P5P E 3 12  ? 110.668 161.792 131.181 1.00 173.46 ? 33  P5P N "C5'" 1 
HETATM 5246 O "O5'" . P5P E 3 12  ? 111.331 160.809 131.960 1.00 174.91 ? 33  P5P N "O5'" 1 
HETATM 5247 P P     . P5P E 3 12  ? 110.528 159.940 133.025 1.00 178.91 ? 33  P5P N P     1 
HETATM 5248 O OP1   . P5P E 3 12  ? 109.400 159.289 132.312 1.00 161.75 ? 33  P5P N OP1   1 
HETATM 5249 O OP2   . P5P E 3 12  ? 111.501 159.104 133.771 1.00 173.66 ? 33  P5P N OP2   1 
HETATM 5250 N N1    . P5P E 3 13  ? 121.070 159.881 132.645 1.00 155.31 ? 34  P5P N N1    1 
HETATM 5251 C C2    . P5P E 3 13  ? 121.546 160.662 131.668 1.00 155.94 ? 34  P5P N C2    1 
HETATM 5252 N N3    . P5P E 3 13  ? 120.889 161.483 130.853 1.00 158.59 ? 34  P5P N N3    1 
HETATM 5253 C C4    . P5P E 3 13  ? 119.571 161.468 131.117 1.00 162.54 ? 34  P5P N C4    1 
HETATM 5254 C C5    . P5P E 3 13  ? 118.936 160.715 132.087 1.00 161.84 ? 34  P5P N C5    1 
HETATM 5255 C C6    . P5P E 3 13  ? 119.742 159.887 132.886 1.00 156.93 ? 34  P5P N C6    1 
HETATM 5256 N N7    . P5P E 3 13  ? 117.569 160.942 132.070 1.00 163.55 ? 34  P5P N N7    1 
HETATM 5257 C C8    . P5P E 3 13  ? 117.407 161.816 131.108 1.00 164.36 ? 34  P5P N C8    1 
HETATM 5258 N N9    . P5P E 3 13  ? 118.575 162.174 130.483 1.00 164.23 ? 34  P5P N N9    1 
HETATM 5259 C "C1'" . P5P E 3 13  ? 118.710 163.130 129.368 1.00 162.89 ? 34  P5P N "C1'" 1 
HETATM 5260 C "C2'" . P5P E 3 13  ? 119.558 162.572 128.226 1.00 160.08 ? 34  P5P N "C2'" 1 
HETATM 5261 O "O2'" . P5P E 3 13  ? 120.182 163.653 127.546 1.00 161.94 ? 34  P5P N "O2'" 1 
HETATM 5262 C "C3'" . P5P E 3 13  ? 118.494 161.918 127.359 1.00 158.67 ? 34  P5P N "C3'" 1 
HETATM 5263 O "O3'" . P5P E 3 13  ? 118.898 161.707 126.018 1.00 157.28 ? 34  P5P N "O3'" 1 
HETATM 5264 C "C4'" . P5P E 3 13  ? 117.321 162.880 127.492 1.00 159.47 ? 34  P5P N "C4'" 1 
HETATM 5265 O "O4'" . P5P E 3 13  ? 117.420 163.380 128.853 1.00 162.23 ? 34  P5P N "O4'" 1 
HETATM 5266 C "C5'" . P5P E 3 13  ? 115.956 162.282 127.267 1.00 160.65 ? 34  P5P N "C5'" 1 
HETATM 5267 O "O5'" . P5P E 3 13  ? 115.014 162.750 128.220 1.00 166.27 ? 34  P5P N "O5'" 1 
HETATM 5268 P P     . P5P E 3 13  ? 113.649 163.423 127.752 1.00 177.89 ? 34  P5P N P     1 
HETATM 5269 O OP1   . P5P E 3 13  ? 113.766 164.890 127.956 1.00 179.55 ? 34  P5P N OP1   1 
HETATM 5270 O OP2   . P5P E 3 13  ? 113.311 162.895 126.406 1.00 159.57 ? 34  P5P N OP2   1 
HETATM 5271 N N1    . P5P E 3 14  ? 119.393 155.688 132.845 1.00 136.76 ? 35  P5P N N1    1 
HETATM 5272 C C2    . P5P E 3 14  ? 120.694 155.696 132.525 1.00 139.68 ? 35  P5P N C2    1 
HETATM 5273 N N3    . P5P E 3 14  ? 121.328 156.414 131.602 1.00 143.97 ? 35  P5P N N3    1 
HETATM 5274 C C4    . P5P E 3 14  ? 120.467 157.213 130.949 1.00 147.13 ? 35  P5P N C4    1 
HETATM 5275 C C5    . P5P E 3 14  ? 119.105 157.314 131.162 1.00 144.10 ? 35  P5P N C5    1 
HETATM 5276 C C6    . P5P E 3 14  ? 118.555 156.504 132.168 1.00 138.19 ? 35  P5P N C6    1 
HETATM 5277 N N7    . P5P E 3 14  ? 118.540 158.243 130.302 1.00 145.26 ? 35  P5P N N7    1 
HETATM 5278 C C8    . P5P E 3 14  ? 119.556 158.673 129.594 1.00 148.64 ? 35  P5P N C8    1 
HETATM 5279 N N9    . P5P E 3 14  ? 120.751 158.092 129.932 1.00 150.78 ? 35  P5P N N9    1 
HETATM 5280 C "C1'" . P5P E 3 14  ? 122.076 158.364 129.344 1.00 151.37 ? 35  P5P N "C1'" 1 
HETATM 5281 C "C2'" . P5P E 3 14  ? 122.617 157.182 128.545 1.00 148.18 ? 35  P5P N "C2'" 1 
HETATM 5282 O "O2'" . P5P E 3 14  ? 124.031 157.153 128.665 1.00 146.36 ? 35  P5P N "O2'" 1 
HETATM 5283 C "C3'" . P5P E 3 14  ? 122.191 157.548 127.129 1.00 149.58 ? 35  P5P N "C3'" 1 
HETATM 5284 O "O3'" . P5P E 3 14  ? 122.969 156.922 126.122 1.00 149.08 ? 35  P5P N "O3'" 1 
HETATM 5285 C "C4'" . P5P E 3 14  ? 122.327 159.064 127.121 1.00 150.70 ? 35  P5P N "C4'" 1 
HETATM 5286 O "O4'" . P5P E 3 14  ? 121.960 159.462 128.466 1.00 154.08 ? 35  P5P N "O4'" 1 
HETATM 5287 C "C5'" . P5P E 3 14  ? 121.467 159.800 126.125 1.00 149.18 ? 35  P5P N "C5'" 1 
HETATM 5288 O "O5'" . P5P E 3 14  ? 120.091 159.501 126.308 1.00 147.32 ? 35  P5P N "O5'" 1 
HETATM 5289 P P     . P5P E 3 14  ? 118.975 160.215 125.424 1.00 156.58 ? 35  P5P N P     1 
HETATM 5290 O OP1   . P5P E 3 14  ? 119.481 160.302 124.032 1.00 150.26 ? 35  P5P N OP1   1 
HETATM 5291 O OP2   . P5P E 3 14  ? 117.681 159.540 125.697 1.00 150.22 ? 35  P5P N OP2   1 
HETATM 5292 N N1    . P5P E 3 15  ? 116.442 153.829 130.518 1.00 122.77 ? 36  P5P N N1    1 
HETATM 5293 C C2    . P5P E 3 15  ? 117.288 153.006 131.151 1.00 124.33 ? 36  P5P N C2    1 
HETATM 5294 N N3    . P5P E 3 15  ? 118.584 152.800 130.932 1.00 126.24 ? 36  P5P N N3    1 
HETATM 5295 C C4    . P5P E 3 15  ? 119.020 153.565 129.918 1.00 132.17 ? 36  P5P N C4    1 
HETATM 5296 C C5    . P5P E 3 15  ? 118.271 154.458 129.173 1.00 132.12 ? 36  P5P N C5    1 
HETATM 5297 C C6    . P5P E 3 15  ? 116.912 154.584 129.502 1.00 123.92 ? 36  P5P N C6    1 
HETATM 5298 N N7    . P5P E 3 15  ? 119.056 155.071 128.208 1.00 137.28 ? 36  P5P N N7    1 
HETATM 5299 C C8    . P5P E 3 15  ? 120.243 154.544 128.388 1.00 138.97 ? 36  P5P N C8    1 
HETATM 5300 N N9    . P5P E 3 15  ? 120.294 153.626 129.406 1.00 138.06 ? 36  P5P N N9    1 
HETATM 5301 C "C1'" . P5P E 3 15  ? 121.462 152.855 129.872 1.00 137.51 ? 36  P5P N "C1'" 1 
HETATM 5302 C "C2'" . P5P E 3 15  ? 121.542 151.472 129.224 1.00 129.27 ? 36  P5P N "C2'" 1 
HETATM 5303 O "O2'" . P5P E 3 15  ? 122.072 150.552 130.167 1.00 120.47 ? 36  P5P N "O2'" 1 
HETATM 5304 C "C3'" . P5P E 3 15  ? 122.519 151.719 128.080 1.00 129.77 ? 36  P5P N "C3'" 1 
HETATM 5305 O "O3'" . P5P E 3 15  ? 123.182 150.545 127.644 1.00 126.35 ? 36  P5P N "O3'" 1 
HETATM 5306 C "C4'" . P5P E 3 15  ? 123.473 152.748 128.667 1.00 133.65 ? 36  P5P N "C4'" 1 
HETATM 5307 O "O4'" . P5P E 3 15  ? 122.636 153.559 129.531 1.00 136.68 ? 36  P5P N "O4'" 1 
HETATM 5308 C "C5'" . P5P E 3 15  ? 124.176 153.639 127.675 1.00 138.52 ? 36  P5P N "C5'" 1 
HETATM 5309 O "O5'" . P5P E 3 15  ? 123.456 154.844 127.469 1.00 143.73 ? 36  P5P N "O5'" 1 
HETATM 5310 P P     . P5P E 3 15  ? 123.028 155.318 126.009 1.00 148.92 ? 36  P5P N P     1 
HETATM 5311 O OP1   . P5P E 3 15  ? 124.124 154.964 125.071 1.00 144.61 ? 36  P5P N OP1   1 
HETATM 5312 O OP2   . P5P E 3 15  ? 121.653 154.824 125.746 1.00 134.66 ? 36  P5P N OP2   1 
HETATM 5313 P P     . Y5P E 3 16  ? 123.341 150.231 126.076 1.00 130.98 ? 37  Y5P N P     1 
HETATM 5314 C "C5'" . Y5P E 3 16  ? 121.075 149.227 125.221 1.00 114.36 ? 37  Y5P N "C5'" 1 
HETATM 5315 O "O5'" . Y5P E 3 16  ? 121.862 150.374 125.505 1.00 119.61 ? 37  Y5P N "O5'" 1 
HETATM 5316 C "C4'" . Y5P E 3 16  ? 120.594 148.556 126.482 1.00 113.65 ? 37  Y5P N "C4'" 1 
HETATM 5317 O "O4'" . Y5P E 3 16  ? 119.975 149.538 127.352 1.00 114.30 ? 37  Y5P N "O4'" 1 
HETATM 5318 C "C3'" . Y5P E 3 16  ? 119.523 147.492 126.295 1.00 108.34 ? 37  Y5P N "C3'" 1 
HETATM 5319 O "O3'" . Y5P E 3 16  ? 120.057 146.233 125.931 1.00 104.15 ? 37  Y5P N "O3'" 1 
HETATM 5320 C "C2'" . Y5P E 3 16  ? 118.816 147.488 127.643 1.00 108.74 ? 37  Y5P N "C2'" 1 
HETATM 5321 O "O2'" . Y5P E 3 16  ? 119.545 146.737 128.604 1.00 108.24 ? 37  Y5P N "O2'" 1 
HETATM 5322 C "C1'" . Y5P E 3 16  ? 118.870 148.967 128.018 1.00 110.04 ? 37  Y5P N "C1'" 1 
HETATM 5323 N N1    . Y5P E 3 16  ? 117.652 149.695 127.601 1.00 107.28 ? 37  Y5P N N1    1 
HETATM 5324 C C2    . Y5P E 3 16  ? 116.488 149.462 128.302 1.00 99.70  ? 37  Y5P N C2    1 
HETATM 5325 N N3    . Y5P E 3 16  ? 115.403 150.172 127.863 1.00 90.42  ? 37  Y5P N N3    1 
HETATM 5326 C C4    . Y5P E 3 16  ? 115.369 151.074 126.821 1.00 95.06  ? 37  Y5P N C4    1 
HETATM 5327 C C6    . Y5P E 3 16  ? 117.687 150.584 126.555 1.00 108.09 ? 37  Y5P N C6    1 
HETATM 5328 O OP1   . Y5P E 3 16  ? 123.750 148.811 125.939 1.00 124.29 ? 37  Y5P N OP1   1 
HETATM 5329 O OP2   . Y5P E 3 16  ? 124.180 151.290 125.462 1.00 133.60 ? 37  Y5P N OP2   1 
HETATM 5330 C C5    . Y5P E 3 16  ? 116.614 151.266 126.147 1.00 102.99 ? 37  Y5P N C5    1 
HETATM 5331 P P     . Y5P E 3 17  ? 119.909 145.700 124.425 1.00 113.20 ? 38  Y5P N P     1 
HETATM 5332 C "C5'" . Y5P E 3 17  ? 119.465 143.294 125.363 1.00 92.33  ? 38  Y5P N "C5'" 1 
HETATM 5333 O "O5'" . Y5P E 3 17  ? 120.245 144.149 124.535 1.00 100.14 ? 38  Y5P N "O5'" 1 
HETATM 5334 C "C4'" . Y5P E 3 17  ? 119.737 141.841 125.071 1.00 98.02  ? 38  Y5P N "C4'" 1 
HETATM 5335 O "O4'" . Y5P E 3 17  ? 119.318 141.549 123.709 1.00 102.61 ? 38  Y5P N "O4'" 1 
HETATM 5336 C "C3'" . Y5P E 3 17  ? 121.202 141.430 125.160 1.00 100.00 ? 38  Y5P N "C3'" 1 
HETATM 5337 O "O3'" . Y5P E 3 17  ? 121.304 140.081 125.617 1.00 101.86 ? 38  Y5P N "O3'" 1 
HETATM 5338 C "C2'" . Y5P E 3 17  ? 121.667 141.523 123.712 1.00 99.80  ? 38  Y5P N "C2'" 1 
HETATM 5339 O "O2'" . Y5P E 3 17  ? 122.786 140.722 123.404 1.00 104.06 ? 38  Y5P N "O2'" 1 
HETATM 5340 C "C1'" . Y5P E 3 17  ? 120.419 141.067 122.962 1.00 95.62  ? 38  Y5P N "C1'" 1 
HETATM 5341 N N1    . Y5P E 3 17  ? 120.311 141.599 121.595 1.00 88.63  ? 38  Y5P N N1    1 
HETATM 5342 C C2    . Y5P E 3 17  ? 120.367 140.712 120.538 1.00 91.10  ? 38  Y5P N C2    1 
HETATM 5343 N N3    . Y5P E 3 17  ? 120.255 141.287 119.298 1.00 91.55  ? 38  Y5P N N3    1 
HETATM 5344 C C4    . Y5P E 3 17  ? 120.095 142.626 119.013 1.00 85.10  ? 38  Y5P N C4    1 
HETATM 5345 C C6    . Y5P E 3 17  ? 120.152 142.946 121.377 1.00 84.93  ? 38  Y5P N C6    1 
HETATM 5346 O OP1   . Y5P E 3 17  ? 120.960 146.345 123.599 1.00 112.19 ? 38  Y5P N OP1   1 
HETATM 5347 O OP2   . Y5P E 3 17  ? 118.485 145.835 124.032 1.00 109.47 ? 38  Y5P N OP2   1 
HETATM 5348 C C5    . Y5P E 3 17  ? 120.046 143.481 120.158 1.00 81.25  ? 38  Y5P N C5    1 
HETATM 5349 P P     . Y5P E 3 18  ? 121.472 139.766 127.183 1.00 105.68 ? 39  Y5P N P     1 
HETATM 5350 C "C5'" . Y5P E 3 18  ? 123.356 141.411 127.952 1.00 102.67 ? 39  Y5P N "C5'" 1 
HETATM 5351 O "O5'" . Y5P E 3 18  ? 122.995 140.119 127.490 1.00 102.03 ? 39  Y5P N "O5'" 1 
HETATM 5352 C "C4'" . Y5P E 3 18  ? 124.837 141.526 128.204 1.00 103.48 ? 39  Y5P N "C4'" 1 
HETATM 5353 O "O4'" . Y5P E 3 18  ? 125.159 142.904 128.522 1.00 102.35 ? 39  Y5P N "O4'" 1 
HETATM 5354 C "C3'" . Y5P E 3 18  ? 125.374 140.726 129.382 1.00 106.03 ? 39  Y5P N "C3'" 1 
HETATM 5355 O "O3'" . Y5P E 3 18  ? 125.662 139.382 129.037 1.00 111.43 ? 39  Y5P N "O3'" 1 
HETATM 5356 C "C2'" . Y5P E 3 18  ? 126.605 141.520 129.800 1.00 108.03 ? 39  Y5P N "C2'" 1 
HETATM 5357 O "O2'" . Y5P E 3 18  ? 127.721 141.209 128.979 1.00 112.25 ? 39  Y5P N "O2'" 1 
HETATM 5358 C "C1'" . Y5P E 3 18  ? 126.162 142.955 129.511 1.00 104.74 ? 39  Y5P N "C1'" 1 
HETATM 5359 N N1    . Y5P E 3 18  ? 125.599 143.626 130.704 1.00 98.65  ? 39  Y5P N N1    1 
HETATM 5360 C C2    . Y5P E 3 18  ? 126.432 144.434 131.453 1.00 96.74  ? 39  Y5P N C2    1 
HETATM 5361 N N3    . Y5P E 3 18  ? 125.834 145.025 132.538 1.00 97.54  ? 39  Y5P N N3    1 
HETATM 5362 C C4    . Y5P E 3 18  ? 124.520 144.894 132.939 1.00 92.95  ? 39  Y5P N C4    1 
HETATM 5363 C C6    . Y5P E 3 18  ? 124.279 143.453 131.049 1.00 97.17  ? 39  Y5P N C6    1 
HETATM 5364 O OP1   . Y5P E 3 18  ? 121.289 138.307 127.388 1.00 105.93 ? 39  Y5P N OP1   1 
HETATM 5365 O OP2   . Y5P E 3 18  ? 120.623 140.727 127.929 1.00 106.45 ? 39  Y5P N OP2   1 
HETATM 5366 C C5    . Y5P E 3 18  ? 123.721 144.041 132.113 1.00 94.69  ? 39  Y5P N C5    1 
HETATM 5367 N N1    . P5P E 3 19  ? 125.116 134.668 137.265 1.00 117.73 ? 40  P5P N N1    1 
HETATM 5368 C C2    . P5P E 3 19  ? 126.391 134.400 136.959 1.00 119.02 ? 40  P5P N C2    1 
HETATM 5369 N N3    . P5P E 3 19  ? 127.202 135.022 136.108 1.00 120.18 ? 40  P5P N N3    1 
HETATM 5370 C C4    . P5P E 3 19  ? 126.571 136.052 135.520 1.00 115.61 ? 40  P5P N C4    1 
HETATM 5371 C C5    . P5P E 3 19  ? 125.263 136.449 135.730 1.00 113.82 ? 40  P5P N C5    1 
HETATM 5372 C C6    . P5P E 3 19  ? 124.509 135.708 136.655 1.00 116.82 ? 40  P5P N C6    1 
HETATM 5373 N N7    . P5P E 3 19  ? 124.953 137.551 134.946 1.00 107.78 ? 40  P5P N N7    1 
HETATM 5374 C C8    . P5P E 3 19  ? 126.061 137.790 134.290 1.00 110.61 ? 40  P5P N C8    1 
HETATM 5375 N N9    . P5P E 3 19  ? 127.081 136.922 134.588 1.00 113.39 ? 40  P5P N N9    1 
HETATM 5376 C "C1'" . P5P E 3 19  ? 128.442 136.914 134.019 1.00 118.13 ? 40  P5P N "C1'" 1 
HETATM 5377 C "C2'" . P5P E 3 19  ? 128.774 135.573 133.369 1.00 122.31 ? 40  P5P N "C2'" 1 
HETATM 5378 O "O2'" . P5P E 3 19  ? 130.178 135.367 133.429 1.00 125.15 ? 40  P5P N "O2'" 1 
HETATM 5379 C "C3'" . P5P E 3 19  ? 128.314 135.816 131.939 1.00 126.17 ? 40  P5P N "C3'" 1 
HETATM 5380 O "O3'" . P5P E 3 19  ? 128.896 134.932 130.996 1.00 132.31 ? 40  P5P N "O3'" 1 
HETATM 5381 C "C4'" . P5P E 3 19  ? 128.698 137.271 131.711 1.00 125.71 ? 40  P5P N "C4'" 1 
HETATM 5382 O "O4'" . P5P E 3 19  ? 128.499 137.899 133.008 1.00 125.62 ? 40  P5P N "O4'" 1 
HETATM 5383 C "C5'" . P5P E 3 19  ? 127.898 138.005 130.664 1.00 119.76 ? 40  P5P N "C5'" 1 
HETATM 5384 O "O5'" . P5P E 3 19  ? 126.561 138.226 131.093 1.00 119.32 ? 40  P5P N "O5'" 1 
HETATM 5385 P P     . P5P E 3 19  ? 125.349 138.184 130.060 1.00 116.43 ? 40  P5P N P     1 
HETATM 5386 O OP1   . P5P E 3 19  ? 125.440 136.909 129.306 1.00 117.72 ? 40  P5P N OP1   1 
HETATM 5387 O OP2   . P5P E 3 19  ? 124.102 138.512 130.795 1.00 116.09 ? 40  P5P N OP2   1 
HETATM 5388 P P     . Y5P E 3 20  ? 128.007 133.782 130.311 1.00 135.84 ? 41  Y5P N P     1 
HETATM 5389 C "C5'" . Y5P E 3 20  ? 128.752 132.038 132.121 1.00 130.01 ? 41  Y5P N "C5'" 1 
HETATM 5390 O "O5'" . Y5P E 3 20  ? 127.703 132.766 131.500 1.00 131.24 ? 41  Y5P N "O5'" 1 
HETATM 5391 C "C4'" . Y5P E 3 20  ? 128.239 131.172 133.246 1.00 130.18 ? 41  Y5P N "C4'" 1 
HETATM 5392 O "O4'" . Y5P E 3 20  ? 127.659 132.003 134.286 1.00 127.89 ? 41  Y5P N "O4'" 1 
HETATM 5393 C "C3'" . Y5P E 3 20  ? 127.126 130.200 132.887 1.00 130.74 ? 41  Y5P N "C3'" 1 
HETATM 5394 O "O3'" . Y5P E 3 20  ? 127.600 129.018 132.266 1.00 128.64 ? 41  Y5P N "O3'" 1 
HETATM 5395 C "C2'" . Y5P E 3 20  ? 126.454 129.958 134.231 1.00 126.98 ? 41  Y5P N "C2'" 1 
HETATM 5396 O "O2'" . Y5P E 3 20  ? 127.191 129.030 135.014 1.00 120.78 ? 41  Y5P N "O2'" 1 
HETATM 5397 C "C1'" . Y5P E 3 20  ? 126.559 131.340 134.874 1.00 126.08 ? 41  Y5P N "C1'" 1 
HETATM 5398 N N1    . Y5P E 3 20  ? 125.341 132.151 134.650 1.00 126.07 ? 41  Y5P N N1    1 
HETATM 5399 C C2    . Y5P E 3 20  ? 124.192 131.784 135.323 1.00 123.59 ? 41  Y5P N C2    1 
HETATM 5400 N N3    . Y5P E 3 20  ? 123.098 132.573 135.073 1.00 120.00 ? 41  Y5P N N3    1 
HETATM 5401 C C4    . Y5P E 3 20  ? 123.040 133.670 134.239 1.00 118.86 ? 41  Y5P N C4    1 
HETATM 5402 C C6    . Y5P E 3 20  ? 125.349 133.236 133.805 1.00 123.63 ? 41  Y5P N C6    1 
HETATM 5403 O OP1   . Y5P E 3 20  ? 128.856 133.079 129.315 1.00 125.21 ? 41  Y5P N OP1   1 
HETATM 5404 O OP2   . Y5P E 3 20  ? 126.722 134.387 129.879 1.00 132.91 ? 41  Y5P N OP2   1 
HETATM 5405 C C5    . Y5P E 3 20  ? 124.268 133.990 133.579 1.00 121.47 ? 41  Y5P N C5    1 
# 
