data_9HB3
# 
_entry.id   9HB3 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9HB3         pdb_00009hb3 10.2210/pdb9hb3/pdb 
WWPDB D_1292142940 ?            ?                   
EMDB  EMD-52012    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-04 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9HB3 
_pdbx_database_status.recvd_initial_deposition_date   2024-11-05 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 
;consensus refinement (cryo-EM structure of inactive human arginine-vasopressin (AVP) V2 receptor (V2R) with Mambaquaretin1 K39A (MQK39A))
;
EMD-52011 'consensus EM volume'  
EMDB 
'V2R-MQ39A (cryo-EM structure of inactive human arginine-vasopressin (AVP) V2 receptor (V2R) with Mambaquaretin1 K39A (MQK39A))' 
EMD-52008 'focused EM volume'    
EMDB 'MQ39A (cryo-EM structure of inactive human arginine-vasopressin (AVP) V2 receptor (V2R) with Mambaquaretin1 K39A (MQK39A))' 
EMD-52009 'focused EM volume'    
EMDB 'Fab-Nb (cryo-EM structure of inactive human arginine-vasopressin (AVP) V2 receptor (V2R) with Mambaquaretin1 K39A (MQK39A))' 
EMD-52010 'focused EM volume'    
EMDB 'cryo-EM structure of inactive human arginine-vasopressin (AVP) V2 receptor (V2R) with Mambaquaretin1 K39A (MQK39A)' 
EMD-52012 'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
6 bernard.mouillac@igf.cnrs.fr  Mouillac  Bernard ? 'principal investigator/group leader' 0000-0002-3906-8673 
7 sebastien.granier@igf.cnrs.fr Sebastien Granier ? 'principal investigator/group leader' 0000-0003-1550-3658 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Bous, J.'      1  0000-0002-3459-7592 
'Fouillen, A.'  2  0000-0002-0326-9932 
'Couvineau, P.' 3  0000-0002-4905-7740 
'Orcel, H.'     4  0000-0002-8699-088X 
'Mary, C.'      5  0000-0003-3056-8839 
'Mendre, C.'    6  0000-0002-3111-2131 
'Schulte, G.'   7  0000-0002-2700-7013 
'Granier, S.'   8  0000-0003-1550-3658 
'Gilles, N.'    9  0000-0001-6853-9764 
'Mouillac, B.'  10 0000-0002-3906-8673 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                3899 
_citation.page_last                 3899 
_citation.title                     
'Inactive structures of the vasopressin V2 receptor reveal distinct binding modes for Tolvaptan and Mambaquaretin toxin.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-59114-5 
_citation.pdbx_database_id_PubMed   40274867 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Fouillen, A.'  1  0000-0002-0326-9932 
primary 'Bous, J.'      2  0000-0002-3459-7592 
primary 'Couvineau, P.' 3  0000-0002-4905-7740 
primary 'Orcel, H.'     4  0000-0002-8699-088X 
primary 'Mary, C.'      5  ?                   
primary 'Lafleur, L.'   6  ?                   
primary 'Pierre, T.'    7  ?                   
primary 'Mendre, C.'    8  0000-0002-3111-2131 
primary 'Gilles, N.'    9  0000-0001-6853-9764 
primary 'Schulte, G.'   10 0000-0002-2700-7013 
primary 'Granier, S.'   11 0000-0003-1550-3658 
primary 'Mouillac, B.'  12 0000-0002-3906-8673 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer syn Mambaquaretin-1                                                                                     6329.218  1 ? ? 
? ? 
2 polymer man 'Synthetic antibody, anti-BRIL Fab fragment, Heavy chain'                                           24539.314 1 ? ? 
? ? 
3 polymer man 'anti-BRIL Fab Nanobody'                                                                            15654.138 1 ? ? 
? ? 
4 polymer man 'Synthetic antibody, anti-BRIL Fab fragment, Light chain'                                           23541.164 1 ? ? 
? ? 
5 polymer man 'arginine-vasopressin (AVP) V2 receptor (V2R)-BRIL,Vasopressin V2 receptor,Vasopressin V2 receptor' 60330.078 1 ? ? 
? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 MQ-1,MQ1,Upsilon-Da2a                                                                
5 'V2R,AVPR V2,Antidiuretic hormone receptor,Renal-type arginine vasopressin receptor' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no RPSFCNLPVKPGPCNGFFSAFYYSQKTNKCHSFTYGGCAGNANRFSTIEKCRRTCVG 
RPSFCNLPVKPGPCNGFFSAFYYSQKTNKCHSFTYGGCAGNANRFSTIEKCRRTCVG A ? 
2 'polypeptide(L)' no no 
;EISEVQLVESGGGLVQPGGSLRLSCAASGFNVVDFSLHWVRQAPGKGLEWVAYISSSSGSTSYADSVKGRFTISADTSKN
TAYLQMNSLRAEDTAVYYCARWGYWPGEPWWKAFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYF
PEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCD
;
;EISEVQLVESGGGLVQPGGSLRLSCAASGFNVVDFSLHWVRQAPGKGLEWVAYISSSSGSTSYADSVKGRFTISADTSKN
TAYLQMNSLRAEDTAVYYCARWGYWPGEPWWKAFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYF
PEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCD
;
H ? 
3 'polypeptide(L)' no no 
;AQPAMAQVQLQESGGGLVQPGGSLRLSCAASGRTISRYAMSWFRQAPGKEREFVAVARRSGDGAFYADSVQGRFTVSRDD
AKNTVYLQMNSLKPEDTAVYYCAIDSDTFYSGSYDYWGQGTQVTVSSLEDYKDDKHHHHHH
;
;AQPAMAQVQLQESGGGLVQPGGSLRLSCAASGRTISRYAMSWFRQAPGKEREFVAVARRSGDGAFYADSVQGRFTVSRDD
AKNTVYLQMNSLKPEDTAVYYCAIDSDTFYSGSYDYWGQGTQVTVSSLEDYKDDKHHHHHH
;
K ? 
4 'polypeptide(L)' no no 
;DIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQP
EDFATYYCQQYLYYSLVTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS
QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;DIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQP
EDFATYYCQQYLYYSLVTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS
QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
L ? 
5 'polypeptide(L)' no no 
;MKTIIALSYIFCLVFADYKDDDDAWSHPQFEKGGGSGGGSGGGSWSHPQFEKLEVLQGPDYKDDDDAASTTSAVPGHPSL
PSLPSQSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQ
LAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLF
IFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSP
GEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSEL
RSLLCCARGRTPPSLGPQDESCTTASSSLAKDTSSARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDA
QKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLRARSTL
;
;MKTIIALSYIFCLVFADYKDDDDAWSHPQFEKGGGSGGGSGGGSWSHPQFEKLEVLQGPDYKDDDDAASTTSAVPGHPSL
PSLPSQSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQ
LAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLF
IFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSP
GEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSEL
RSLLCCARGRTPPSLGPQDESCTTASSSLAKDTSSARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDA
QKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLRARSTL
;
R ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ARG n 
1 2   PRO n 
1 3   SER n 
1 4   PHE n 
1 5   CYS n 
1 6   ASN n 
1 7   LEU n 
1 8   PRO n 
1 9   VAL n 
1 10  LYS n 
1 11  PRO n 
1 12  GLY n 
1 13  PRO n 
1 14  CYS n 
1 15  ASN n 
1 16  GLY n 
1 17  PHE n 
1 18  PHE n 
1 19  SER n 
1 20  ALA n 
1 21  PHE n 
1 22  TYR n 
1 23  TYR n 
1 24  SER n 
1 25  GLN n 
1 26  LYS n 
1 27  THR n 
1 28  ASN n 
1 29  LYS n 
1 30  CYS n 
1 31  HIS n 
1 32  SER n 
1 33  PHE n 
1 34  THR n 
1 35  TYR n 
1 36  GLY n 
1 37  GLY n 
1 38  CYS n 
1 39  ALA n 
1 40  GLY n 
1 41  ASN n 
1 42  ALA n 
1 43  ASN n 
1 44  ARG n 
1 45  PHE n 
1 46  SER n 
1 47  THR n 
1 48  ILE n 
1 49  GLU n 
1 50  LYS n 
1 51  CYS n 
1 52  ARG n 
1 53  ARG n 
1 54  THR n 
1 55  CYS n 
1 56  VAL n 
1 57  GLY n 
2 1   GLU n 
2 2   ILE n 
2 3   SER n 
2 4   GLU n 
2 5   VAL n 
2 6   GLN n 
2 7   LEU n 
2 8   VAL n 
2 9   GLU n 
2 10  SER n 
2 11  GLY n 
2 12  GLY n 
2 13  GLY n 
2 14  LEU n 
2 15  VAL n 
2 16  GLN n 
2 17  PRO n 
2 18  GLY n 
2 19  GLY n 
2 20  SER n 
2 21  LEU n 
2 22  ARG n 
2 23  LEU n 
2 24  SER n 
2 25  CYS n 
2 26  ALA n 
2 27  ALA n 
2 28  SER n 
2 29  GLY n 
2 30  PHE n 
2 31  ASN n 
2 32  VAL n 
2 33  VAL n 
2 34  ASP n 
2 35  PHE n 
2 36  SER n 
2 37  LEU n 
2 38  HIS n 
2 39  TRP n 
2 40  VAL n 
2 41  ARG n 
2 42  GLN n 
2 43  ALA n 
2 44  PRO n 
2 45  GLY n 
2 46  LYS n 
2 47  GLY n 
2 48  LEU n 
2 49  GLU n 
2 50  TRP n 
2 51  VAL n 
2 52  ALA n 
2 53  TYR n 
2 54  ILE n 
2 55  SER n 
2 56  SER n 
2 57  SER n 
2 58  SER n 
2 59  GLY n 
2 60  SER n 
2 61  THR n 
2 62  SER n 
2 63  TYR n 
2 64  ALA n 
2 65  ASP n 
2 66  SER n 
2 67  VAL n 
2 68  LYS n 
2 69  GLY n 
2 70  ARG n 
2 71  PHE n 
2 72  THR n 
2 73  ILE n 
2 74  SER n 
2 75  ALA n 
2 76  ASP n 
2 77  THR n 
2 78  SER n 
2 79  LYS n 
2 80  ASN n 
2 81  THR n 
2 82  ALA n 
2 83  TYR n 
2 84  LEU n 
2 85  GLN n 
2 86  MET n 
2 87  ASN n 
2 88  SER n 
2 89  LEU n 
2 90  ARG n 
2 91  ALA n 
2 92  GLU n 
2 93  ASP n 
2 94  THR n 
2 95  ALA n 
2 96  VAL n 
2 97  TYR n 
2 98  TYR n 
2 99  CYS n 
2 100 ALA n 
2 101 ARG n 
2 102 TRP n 
2 103 GLY n 
2 104 TYR n 
2 105 TRP n 
2 106 PRO n 
2 107 GLY n 
2 108 GLU n 
2 109 PRO n 
2 110 TRP n 
2 111 TRP n 
2 112 LYS n 
2 113 ALA n 
2 114 PHE n 
2 115 ASP n 
2 116 TYR n 
2 117 TRP n 
2 118 GLY n 
2 119 GLN n 
2 120 GLY n 
2 121 THR n 
2 122 LEU n 
2 123 VAL n 
2 124 THR n 
2 125 VAL n 
2 126 SER n 
2 127 SER n 
2 128 ALA n 
2 129 SER n 
2 130 THR n 
2 131 LYS n 
2 132 GLY n 
2 133 PRO n 
2 134 SER n 
2 135 VAL n 
2 136 PHE n 
2 137 PRO n 
2 138 LEU n 
2 139 ALA n 
2 140 PRO n 
2 141 SER n 
2 142 SER n 
2 143 LYS n 
2 144 SER n 
2 145 THR n 
2 146 SER n 
2 147 GLY n 
2 148 GLY n 
2 149 THR n 
2 150 ALA n 
2 151 ALA n 
2 152 LEU n 
2 153 GLY n 
2 154 CYS n 
2 155 LEU n 
2 156 VAL n 
2 157 LYS n 
2 158 ASP n 
2 159 TYR n 
2 160 PHE n 
2 161 PRO n 
2 162 GLU n 
2 163 PRO n 
2 164 VAL n 
2 165 THR n 
2 166 VAL n 
2 167 SER n 
2 168 TRP n 
2 169 ASN n 
2 170 SER n 
2 171 GLY n 
2 172 ALA n 
2 173 LEU n 
2 174 THR n 
2 175 SER n 
2 176 GLY n 
2 177 VAL n 
2 178 HIS n 
2 179 THR n 
2 180 PHE n 
2 181 PRO n 
2 182 ALA n 
2 183 VAL n 
2 184 LEU n 
2 185 GLN n 
2 186 SER n 
2 187 SER n 
2 188 GLY n 
2 189 LEU n 
2 190 TYR n 
2 191 SER n 
2 192 LEU n 
2 193 SER n 
2 194 SER n 
2 195 VAL n 
2 196 VAL n 
2 197 THR n 
2 198 VAL n 
2 199 PRO n 
2 200 SER n 
2 201 SER n 
2 202 SER n 
2 203 LEU n 
2 204 GLY n 
2 205 THR n 
2 206 GLN n 
2 207 THR n 
2 208 TYR n 
2 209 ILE n 
2 210 CYS n 
2 211 ASN n 
2 212 VAL n 
2 213 ASN n 
2 214 HIS n 
2 215 LYS n 
2 216 PRO n 
2 217 SER n 
2 218 ASN n 
2 219 THR n 
2 220 LYS n 
2 221 VAL n 
2 222 ASP n 
2 223 LYS n 
2 224 LYS n 
2 225 VAL n 
2 226 GLU n 
2 227 PRO n 
2 228 LYS n 
2 229 SER n 
2 230 CYS n 
2 231 ASP n 
3 1   ALA n 
3 2   GLN n 
3 3   PRO n 
3 4   ALA n 
3 5   MET n 
3 6   ALA n 
3 7   GLN n 
3 8   VAL n 
3 9   GLN n 
3 10  LEU n 
3 11  GLN n 
3 12  GLU n 
3 13  SER n 
3 14  GLY n 
3 15  GLY n 
3 16  GLY n 
3 17  LEU n 
3 18  VAL n 
3 19  GLN n 
3 20  PRO n 
3 21  GLY n 
3 22  GLY n 
3 23  SER n 
3 24  LEU n 
3 25  ARG n 
3 26  LEU n 
3 27  SER n 
3 28  CYS n 
3 29  ALA n 
3 30  ALA n 
3 31  SER n 
3 32  GLY n 
3 33  ARG n 
3 34  THR n 
3 35  ILE n 
3 36  SER n 
3 37  ARG n 
3 38  TYR n 
3 39  ALA n 
3 40  MET n 
3 41  SER n 
3 42  TRP n 
3 43  PHE n 
3 44  ARG n 
3 45  GLN n 
3 46  ALA n 
3 47  PRO n 
3 48  GLY n 
3 49  LYS n 
3 50  GLU n 
3 51  ARG n 
3 52  GLU n 
3 53  PHE n 
3 54  VAL n 
3 55  ALA n 
3 56  VAL n 
3 57  ALA n 
3 58  ARG n 
3 59  ARG n 
3 60  SER n 
3 61  GLY n 
3 62  ASP n 
3 63  GLY n 
3 64  ALA n 
3 65  PHE n 
3 66  TYR n 
3 67  ALA n 
3 68  ASP n 
3 69  SER n 
3 70  VAL n 
3 71  GLN n 
3 72  GLY n 
3 73  ARG n 
3 74  PHE n 
3 75  THR n 
3 76  VAL n 
3 77  SER n 
3 78  ARG n 
3 79  ASP n 
3 80  ASP n 
3 81  ALA n 
3 82  LYS n 
3 83  ASN n 
3 84  THR n 
3 85  VAL n 
3 86  TYR n 
3 87  LEU n 
3 88  GLN n 
3 89  MET n 
3 90  ASN n 
3 91  SER n 
3 92  LEU n 
3 93  LYS n 
3 94  PRO n 
3 95  GLU n 
3 96  ASP n 
3 97  THR n 
3 98  ALA n 
3 99  VAL n 
3 100 TYR n 
3 101 TYR n 
3 102 CYS n 
3 103 ALA n 
3 104 ILE n 
3 105 ASP n 
3 106 SER n 
3 107 ASP n 
3 108 THR n 
3 109 PHE n 
3 110 TYR n 
3 111 SER n 
3 112 GLY n 
3 113 SER n 
3 114 TYR n 
3 115 ASP n 
3 116 TYR n 
3 117 TRP n 
3 118 GLY n 
3 119 GLN n 
3 120 GLY n 
3 121 THR n 
3 122 GLN n 
3 123 VAL n 
3 124 THR n 
3 125 VAL n 
3 126 SER n 
3 127 SER n 
3 128 LEU n 
3 129 GLU n 
3 130 ASP n 
3 131 TYR n 
3 132 LYS n 
3 133 ASP n 
3 134 ASP n 
3 135 LYS n 
3 136 HIS n 
3 137 HIS n 
3 138 HIS n 
3 139 HIS n 
3 140 HIS n 
3 141 HIS n 
4 1   ASP n 
4 2   ILE n 
4 3   GLN n 
4 4   MET n 
4 5   THR n 
4 6   GLN n 
4 7   SER n 
4 8   PRO n 
4 9   SER n 
4 10  SER n 
4 11  LEU n 
4 12  SER n 
4 13  ALA n 
4 14  SER n 
4 15  VAL n 
4 16  GLY n 
4 17  ASP n 
4 18  ARG n 
4 19  VAL n 
4 20  THR n 
4 21  ILE n 
4 22  THR n 
4 23  CYS n 
4 24  ARG n 
4 25  ALA n 
4 26  SER n 
4 27  GLN n 
4 28  SER n 
4 29  VAL n 
4 30  SER n 
4 31  SER n 
4 32  ALA n 
4 33  VAL n 
4 34  ALA n 
4 35  TRP n 
4 36  TYR n 
4 37  GLN n 
4 38  GLN n 
4 39  LYS n 
4 40  PRO n 
4 41  GLY n 
4 42  LYS n 
4 43  ALA n 
4 44  PRO n 
4 45  LYS n 
4 46  LEU n 
4 47  LEU n 
4 48  ILE n 
4 49  TYR n 
4 50  SER n 
4 51  ALA n 
4 52  SER n 
4 53  SER n 
4 54  LEU n 
4 55  TYR n 
4 56  SER n 
4 57  GLY n 
4 58  VAL n 
4 59  PRO n 
4 60  SER n 
4 61  ARG n 
4 62  PHE n 
4 63  SER n 
4 64  GLY n 
4 65  SER n 
4 66  ARG n 
4 67  SER n 
4 68  GLY n 
4 69  THR n 
4 70  ASP n 
4 71  PHE n 
4 72  THR n 
4 73  LEU n 
4 74  THR n 
4 75  ILE n 
4 76  SER n 
4 77  SER n 
4 78  LEU n 
4 79  GLN n 
4 80  PRO n 
4 81  GLU n 
4 82  ASP n 
4 83  PHE n 
4 84  ALA n 
4 85  THR n 
4 86  TYR n 
4 87  TYR n 
4 88  CYS n 
4 89  GLN n 
4 90  GLN n 
4 91  TYR n 
4 92  LEU n 
4 93  TYR n 
4 94  TYR n 
4 95  SER n 
4 96  LEU n 
4 97  VAL n 
4 98  THR n 
4 99  PHE n 
4 100 GLY n 
4 101 GLN n 
4 102 GLY n 
4 103 THR n 
4 104 LYS n 
4 105 VAL n 
4 106 GLU n 
4 107 ILE n 
4 108 LYS n 
4 109 ARG n 
4 110 THR n 
4 111 VAL n 
4 112 ALA n 
4 113 ALA n 
4 114 PRO n 
4 115 SER n 
4 116 VAL n 
4 117 PHE n 
4 118 ILE n 
4 119 PHE n 
4 120 PRO n 
4 121 PRO n 
4 122 SER n 
4 123 ASP n 
4 124 GLU n 
4 125 GLN n 
4 126 LEU n 
4 127 LYS n 
4 128 SER n 
4 129 GLY n 
4 130 THR n 
4 131 ALA n 
4 132 SER n 
4 133 VAL n 
4 134 VAL n 
4 135 CYS n 
4 136 LEU n 
4 137 LEU n 
4 138 ASN n 
4 139 ASN n 
4 140 PHE n 
4 141 TYR n 
4 142 PRO n 
4 143 ARG n 
4 144 GLU n 
4 145 ALA n 
4 146 LYS n 
4 147 VAL n 
4 148 GLN n 
4 149 TRP n 
4 150 LYS n 
4 151 VAL n 
4 152 ASP n 
4 153 ASN n 
4 154 ALA n 
4 155 LEU n 
4 156 GLN n 
4 157 SER n 
4 158 GLY n 
4 159 ASN n 
4 160 SER n 
4 161 GLN n 
4 162 GLU n 
4 163 SER n 
4 164 VAL n 
4 165 THR n 
4 166 GLU n 
4 167 GLN n 
4 168 ASP n 
4 169 SER n 
4 170 LYS n 
4 171 ASP n 
4 172 SER n 
4 173 THR n 
4 174 TYR n 
4 175 SER n 
4 176 LEU n 
4 177 SER n 
4 178 SER n 
4 179 THR n 
4 180 LEU n 
4 181 THR n 
4 182 LEU n 
4 183 SER n 
4 184 LYS n 
4 185 ALA n 
4 186 ASP n 
4 187 TYR n 
4 188 GLU n 
4 189 LYS n 
4 190 HIS n 
4 191 LYS n 
4 192 VAL n 
4 193 TYR n 
4 194 ALA n 
4 195 CYS n 
4 196 GLU n 
4 197 VAL n 
4 198 THR n 
4 199 HIS n 
4 200 GLN n 
4 201 GLY n 
4 202 LEU n 
4 203 SER n 
4 204 SER n 
4 205 PRO n 
4 206 VAL n 
4 207 THR n 
4 208 LYS n 
4 209 SER n 
4 210 PHE n 
4 211 ASN n 
4 212 ARG n 
4 213 GLY n 
4 214 GLU n 
4 215 CYS n 
5 1   MET n 
5 2   LYS n 
5 3   THR n 
5 4   ILE n 
5 5   ILE n 
5 6   ALA n 
5 7   LEU n 
5 8   SER n 
5 9   TYR n 
5 10  ILE n 
5 11  PHE n 
5 12  CYS n 
5 13  LEU n 
5 14  VAL n 
5 15  PHE n 
5 16  ALA n 
5 17  ASP n 
5 18  TYR n 
5 19  LYS n 
5 20  ASP n 
5 21  ASP n 
5 22  ASP n 
5 23  ASP n 
5 24  ALA n 
5 25  TRP n 
5 26  SER n 
5 27  HIS n 
5 28  PRO n 
5 29  GLN n 
5 30  PHE n 
5 31  GLU n 
5 32  LYS n 
5 33  GLY n 
5 34  GLY n 
5 35  GLY n 
5 36  SER n 
5 37  GLY n 
5 38  GLY n 
5 39  GLY n 
5 40  SER n 
5 41  GLY n 
5 42  GLY n 
5 43  GLY n 
5 44  SER n 
5 45  TRP n 
5 46  SER n 
5 47  HIS n 
5 48  PRO n 
5 49  GLN n 
5 50  PHE n 
5 51  GLU n 
5 52  LYS n 
5 53  LEU n 
5 54  GLU n 
5 55  VAL n 
5 56  LEU n 
5 57  GLN n 
5 58  GLY n 
5 59  PRO n 
5 60  ASP n 
5 61  TYR n 
5 62  LYS n 
5 63  ASP n 
5 64  ASP n 
5 65  ASP n 
5 66  ASP n 
5 67  ALA n 
5 68  ALA n 
5 69  SER n 
5 70  THR n 
5 71  THR n 
5 72  SER n 
5 73  ALA n 
5 74  VAL n 
5 75  PRO n 
5 76  GLY n 
5 77  HIS n 
5 78  PRO n 
5 79  SER n 
5 80  LEU n 
5 81  PRO n 
5 82  SER n 
5 83  LEU n 
5 84  PRO n 
5 85  SER n 
5 86  GLN n 
5 87  SER n 
5 88  SER n 
5 89  GLN n 
5 90  GLU n 
5 91  ARG n 
5 92  PRO n 
5 93  LEU n 
5 94  ASP n 
5 95  THR n 
5 96  ARG n 
5 97  ASP n 
5 98  PRO n 
5 99  LEU n 
5 100 LEU n 
5 101 ALA n 
5 102 ARG n 
5 103 ALA n 
5 104 GLU n 
5 105 LEU n 
5 106 ALA n 
5 107 LEU n 
5 108 LEU n 
5 109 SER n 
5 110 ILE n 
5 111 VAL n 
5 112 PHE n 
5 113 VAL n 
5 114 ALA n 
5 115 VAL n 
5 116 ALA n 
5 117 LEU n 
5 118 SER n 
5 119 ASN n 
5 120 GLY n 
5 121 LEU n 
5 122 VAL n 
5 123 LEU n 
5 124 ALA n 
5 125 ALA n 
5 126 LEU n 
5 127 ALA n 
5 128 ARG n 
5 129 ARG n 
5 130 GLY n 
5 131 ARG n 
5 132 ARG n 
5 133 GLY n 
5 134 HIS n 
5 135 TRP n 
5 136 ALA n 
5 137 PRO n 
5 138 ILE n 
5 139 HIS n 
5 140 VAL n 
5 141 PHE n 
5 142 ILE n 
5 143 GLY n 
5 144 HIS n 
5 145 LEU n 
5 146 CYS n 
5 147 LEU n 
5 148 ALA n 
5 149 ASP n 
5 150 LEU n 
5 151 ALA n 
5 152 VAL n 
5 153 ALA n 
5 154 LEU n 
5 155 PHE n 
5 156 GLN n 
5 157 VAL n 
5 158 LEU n 
5 159 PRO n 
5 160 GLN n 
5 161 LEU n 
5 162 ALA n 
5 163 TRP n 
5 164 LYS n 
5 165 ALA n 
5 166 THR n 
5 167 ASP n 
5 168 ARG n 
5 169 PHE n 
5 170 ARG n 
5 171 GLY n 
5 172 PRO n 
5 173 ASP n 
5 174 ALA n 
5 175 LEU n 
5 176 CYS n 
5 177 ARG n 
5 178 ALA n 
5 179 VAL n 
5 180 LYS n 
5 181 TYR n 
5 182 LEU n 
5 183 GLN n 
5 184 MET n 
5 185 VAL n 
5 186 GLY n 
5 187 MET n 
5 188 TYR n 
5 189 ALA n 
5 190 SER n 
5 191 SER n 
5 192 TYR n 
5 193 MET n 
5 194 ILE n 
5 195 LEU n 
5 196 ALA n 
5 197 MET n 
5 198 THR n 
5 199 LEU n 
5 200 ASP n 
5 201 ARG n 
5 202 HIS n 
5 203 ARG n 
5 204 ALA n 
5 205 ILE n 
5 206 CYS n 
5 207 ARG n 
5 208 PRO n 
5 209 MET n 
5 210 LEU n 
5 211 ALA n 
5 212 TYR n 
5 213 ARG n 
5 214 HIS n 
5 215 GLY n 
5 216 SER n 
5 217 GLY n 
5 218 ALA n 
5 219 HIS n 
5 220 TRP n 
5 221 ASN n 
5 222 ARG n 
5 223 PRO n 
5 224 VAL n 
5 225 LEU n 
5 226 VAL n 
5 227 ALA n 
5 228 TRP n 
5 229 ALA n 
5 230 PHE n 
5 231 SER n 
5 232 LEU n 
5 233 LEU n 
5 234 LEU n 
5 235 SER n 
5 236 LEU n 
5 237 PRO n 
5 238 GLN n 
5 239 LEU n 
5 240 PHE n 
5 241 ILE n 
5 242 PHE n 
5 243 ALA n 
5 244 GLN n 
5 245 ARG n 
5 246 ASN n 
5 247 VAL n 
5 248 GLU n 
5 249 GLY n 
5 250 GLY n 
5 251 SER n 
5 252 GLY n 
5 253 VAL n 
5 254 THR n 
5 255 ASP n 
5 256 CYS n 
5 257 TRP n 
5 258 ALA n 
5 259 CYS n 
5 260 PHE n 
5 261 ALA n 
5 262 GLU n 
5 263 PRO n 
5 264 TRP n 
5 265 GLY n 
5 266 ARG n 
5 267 ARG n 
5 268 THR n 
5 269 TYR n 
5 270 VAL n 
5 271 THR n 
5 272 TRP n 
5 273 ILE n 
5 274 ALA n 
5 275 LEU n 
5 276 MET n 
5 277 VAL n 
5 278 PHE n 
5 279 VAL n 
5 280 ALA n 
5 281 PRO n 
5 282 THR n 
5 283 LEU n 
5 284 GLY n 
5 285 ILE n 
5 286 ALA n 
5 287 ALA n 
5 288 CYS n 
5 289 GLN n 
5 290 VAL n 
5 291 LEU n 
5 292 ILE n 
5 293 PHE n 
5 294 ARG n 
5 295 GLU n 
5 296 ILE n 
5 297 HIS n 
5 298 ALA n 
5 299 SER n 
5 300 LEU n 
5 301 VAL n 
5 302 PRO n 
5 303 GLY n 
5 304 PRO n 
5 305 SER n 
5 306 GLU n 
5 307 ARG n 
5 308 PRO n 
5 309 GLY n 
5 310 GLY n 
5 311 ARG n 
5 312 ARG n 
5 313 ARG n 
5 314 GLY n 
5 315 ARG n 
5 316 ARG n 
5 317 THR n 
5 318 GLY n 
5 319 SER n 
5 320 PRO n 
5 321 GLY n 
5 322 GLU n 
5 323 GLY n 
5 324 ALA n 
5 325 HIS n 
5 326 VAL n 
5 327 SER n 
5 328 ALA n 
5 329 ALA n 
5 330 VAL n 
5 331 ALA n 
5 332 LYS n 
5 333 THR n 
5 334 VAL n 
5 335 ARG n 
5 336 MET n 
5 337 THR n 
5 338 LEU n 
5 339 VAL n 
5 340 ILE n 
5 341 VAL n 
5 342 VAL n 
5 343 VAL n 
5 344 TYR n 
5 345 VAL n 
5 346 LEU n 
5 347 CYS n 
5 348 TRP n 
5 349 ALA n 
5 350 PRO n 
5 351 PHE n 
5 352 PHE n 
5 353 LEU n 
5 354 VAL n 
5 355 GLN n 
5 356 LEU n 
5 357 TRP n 
5 358 ALA n 
5 359 ALA n 
5 360 TRP n 
5 361 ASP n 
5 362 PRO n 
5 363 GLU n 
5 364 ALA n 
5 365 PRO n 
5 366 LEU n 
5 367 GLU n 
5 368 GLY n 
5 369 ALA n 
5 370 PRO n 
5 371 PHE n 
5 372 VAL n 
5 373 LEU n 
5 374 LEU n 
5 375 MET n 
5 376 LEU n 
5 377 LEU n 
5 378 ALA n 
5 379 SER n 
5 380 LEU n 
5 381 ASN n 
5 382 SER n 
5 383 CYS n 
5 384 THR n 
5 385 ASN n 
5 386 PRO n 
5 387 TRP n 
5 388 ILE n 
5 389 TYR n 
5 390 ALA n 
5 391 SER n 
5 392 PHE n 
5 393 SER n 
5 394 SER n 
5 395 SER n 
5 396 VAL n 
5 397 SER n 
5 398 SER n 
5 399 GLU n 
5 400 LEU n 
5 401 ARG n 
5 402 SER n 
5 403 LEU n 
5 404 LEU n 
5 405 CYS n 
5 406 CYS n 
5 407 ALA n 
5 408 ARG n 
5 409 GLY n 
5 410 ARG n 
5 411 THR n 
5 412 PRO n 
5 413 PRO n 
5 414 SER n 
5 415 LEU n 
5 416 GLY n 
5 417 PRO n 
5 418 GLN n 
5 419 ASP n 
5 420 GLU n 
5 421 SER n 
5 422 CYS n 
5 423 THR n 
5 424 THR n 
5 425 ALA n 
5 426 SER n 
5 427 SER n 
5 428 SER n 
5 429 LEU n 
5 430 ALA n 
5 431 LYS n 
5 432 ASP n 
5 433 THR n 
5 434 SER n 
5 435 SER n 
5 436 ALA n 
5 437 ARG n 
5 438 ARG n 
5 439 GLN n 
5 440 LEU n 
5 441 ALA n 
5 442 ASP n 
5 443 LEU n 
5 444 GLU n 
5 445 ASP n 
5 446 ASN n 
5 447 TRP n 
5 448 GLU n 
5 449 THR n 
5 450 LEU n 
5 451 ASN n 
5 452 ASP n 
5 453 ASN n 
5 454 LEU n 
5 455 LYS n 
5 456 VAL n 
5 457 ILE n 
5 458 GLU n 
5 459 LYS n 
5 460 ALA n 
5 461 ASP n 
5 462 ASN n 
5 463 ALA n 
5 464 ALA n 
5 465 GLN n 
5 466 VAL n 
5 467 LYS n 
5 468 ASP n 
5 469 ALA n 
5 470 LEU n 
5 471 THR n 
5 472 LYS n 
5 473 MET n 
5 474 ARG n 
5 475 ALA n 
5 476 ALA n 
5 477 ALA n 
5 478 LEU n 
5 479 ASP n 
5 480 ALA n 
5 481 GLN n 
5 482 LYS n 
5 483 ALA n 
5 484 THR n 
5 485 PRO n 
5 486 PRO n 
5 487 LYS n 
5 488 LEU n 
5 489 GLU n 
5 490 ASP n 
5 491 LYS n 
5 492 SER n 
5 493 PRO n 
5 494 ASP n 
5 495 SER n 
5 496 PRO n 
5 497 GLU n 
5 498 MET n 
5 499 LYS n 
5 500 ASP n 
5 501 PHE n 
5 502 ARG n 
5 503 HIS n 
5 504 GLY n 
5 505 PHE n 
5 506 ASP n 
5 507 ILE n 
5 508 LEU n 
5 509 VAL n 
5 510 GLY n 
5 511 GLN n 
5 512 ILE n 
5 513 ASP n 
5 514 ASP n 
5 515 ALA n 
5 516 LEU n 
5 517 LYS n 
5 518 LEU n 
5 519 ALA n 
5 520 ASN n 
5 521 GLU n 
5 522 GLY n 
5 523 LYS n 
5 524 VAL n 
5 525 LYS n 
5 526 GLU n 
5 527 ALA n 
5 528 GLN n 
5 529 ALA n 
5 530 ALA n 
5 531 ALA n 
5 532 GLU n 
5 533 GLN n 
5 534 LEU n 
5 535 LYS n 
5 536 THR n 
5 537 THR n 
5 538 ARG n 
5 539 ASN n 
5 540 ALA n 
5 541 TYR n 
5 542 ILE n 
5 543 GLN n 
5 544 LYS n 
5 545 TYR n 
5 546 LEU n 
5 547 ARG n 
5 548 ALA n 
5 549 ARG n 
5 550 SER n 
5 551 THR n 
5 552 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
2 1 sample 'Biological sequence' 1   231 ?     ? ?                             ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1   141 ?     ? ?                             ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
Escherichia    561  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1   215 ?     ? ?                             ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1   67  ?     ? ?                             ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
Spodoptera     7106 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 2 sample 'Biological sequence' 68  406 human ? 'AVPR2, ADHR, DIR, DIR3, V2R' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
Spodoptera     7106 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 3 sample 'Biological sequence' 407 552 ?     ? ?                             ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
Spodoptera     7106 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_src_syn.entity_id              1 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       57 
_pdbx_entity_src_syn.organism_scientific    'Dendroaspis angusticeps' 
_pdbx_entity_src_syn.organism_common_name   'eastern green mamba' 
_pdbx_entity_src_syn.ncbi_taxonomy_id       8618 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ARG 1   1   ?   ?   ?   A . n 
A 1 2   PRO 2   2   ?   ?   ?   A . n 
A 1 3   SER 3   3   ?   ?   ?   A . n 
A 1 4   PHE 4   4   4   PHE PHE A . n 
A 1 5   CYS 5   5   5   CYS CYS A . n 
A 1 6   ASN 6   6   6   ASN ASN A . n 
A 1 7   LEU 7   7   7   LEU LEU A . n 
A 1 8   PRO 8   8   8   PRO PRO A . n 
A 1 9   VAL 9   9   9   VAL VAL A . n 
A 1 10  LYS 10  10  10  LYS LYS A . n 
A 1 11  PRO 11  11  11  PRO PRO A . n 
A 1 12  GLY 12  12  12  GLY GLY A . n 
A 1 13  PRO 13  13  13  PRO PRO A . n 
A 1 14  CYS 14  14  14  CYS CYS A . n 
A 1 15  ASN 15  15  15  ASN ASN A . n 
A 1 16  GLY 16  16  16  GLY GLY A . n 
A 1 17  PHE 17  17  17  PHE PHE A . n 
A 1 18  PHE 18  18  18  PHE PHE A . n 
A 1 19  SER 19  19  19  SER SER A . n 
A 1 20  ALA 20  20  20  ALA ALA A . n 
A 1 21  PHE 21  21  21  PHE PHE A . n 
A 1 22  TYR 22  22  22  TYR TYR A . n 
A 1 23  TYR 23  23  23  TYR TYR A . n 
A 1 24  SER 24  24  ?   ?   ?   A . n 
A 1 25  GLN 25  25  ?   ?   ?   A . n 
A 1 26  LYS 26  26  ?   ?   ?   A . n 
A 1 27  THR 27  27  ?   ?   ?   A . n 
A 1 28  ASN 28  28  ?   ?   ?   A . n 
A 1 29  LYS 29  29  ?   ?   ?   A . n 
A 1 30  CYS 30  30  30  CYS CYS A . n 
A 1 31  HIS 31  31  31  HIS HIS A . n 
A 1 32  SER 32  32  32  SER SER A . n 
A 1 33  PHE 33  33  33  PHE PHE A . n 
A 1 34  THR 34  34  34  THR THR A . n 
A 1 35  TYR 35  35  35  TYR TYR A . n 
A 1 36  GLY 36  36  36  GLY GLY A . n 
A 1 37  GLY 37  37  37  GLY GLY A . n 
A 1 38  CYS 38  38  38  CYS CYS A . n 
A 1 39  ALA 39  39  39  ALA ALA A . n 
A 1 40  GLY 40  40  40  GLY GLY A . n 
A 1 41  ASN 41  41  41  ASN ASN A . n 
A 1 42  ALA 42  42  42  ALA ALA A . n 
A 1 43  ASN 43  43  43  ASN ASN A . n 
A 1 44  ARG 44  44  44  ARG ARG A . n 
A 1 45  PHE 45  45  45  PHE PHE A . n 
A 1 46  SER 46  46  46  SER SER A . n 
A 1 47  THR 47  47  47  THR THR A . n 
A 1 48  ILE 48  48  48  ILE ILE A . n 
A 1 49  GLU 49  49  49  GLU GLU A . n 
A 1 50  LYS 50  50  50  LYS LYS A . n 
A 1 51  CYS 51  51  51  CYS CYS A . n 
A 1 52  ARG 52  52  52  ARG ARG A . n 
A 1 53  ARG 53  53  53  ARG ARG A . n 
A 1 54  THR 54  54  54  THR THR A . n 
A 1 55  CYS 55  55  55  CYS CYS A . n 
A 1 56  VAL 56  56  56  VAL VAL A . n 
A 1 57  GLY 57  57  ?   ?   ?   A . n 
B 2 1   GLU 1   1   ?   ?   ?   H . n 
B 2 2   ILE 2   2   ?   ?   ?   H . n 
B 2 3   SER 3   3   ?   ?   ?   H . n 
B 2 4   GLU 4   4   4   GLU GLU H . n 
B 2 5   VAL 5   5   5   VAL VAL H . n 
B 2 6   GLN 6   6   6   GLN GLN H . n 
B 2 7   LEU 7   7   7   LEU LEU H . n 
B 2 8   VAL 8   8   8   VAL VAL H . n 
B 2 9   GLU 9   9   9   GLU GLU H . n 
B 2 10  SER 10  10  10  SER SER H . n 
B 2 11  GLY 11  11  11  GLY GLY H . n 
B 2 12  GLY 12  12  12  GLY GLY H . n 
B 2 13  GLY 13  13  13  GLY GLY H . n 
B 2 14  LEU 14  14  14  LEU LEU H . n 
B 2 15  VAL 15  15  15  VAL VAL H . n 
B 2 16  GLN 16  16  16  GLN GLN H . n 
B 2 17  PRO 17  17  17  PRO PRO H . n 
B 2 18  GLY 18  18  18  GLY GLY H . n 
B 2 19  GLY 19  19  19  GLY GLY H . n 
B 2 20  SER 20  20  20  SER SER H . n 
B 2 21  LEU 21  21  21  LEU LEU H . n 
B 2 22  ARG 22  22  22  ARG ARG H . n 
B 2 23  LEU 23  23  23  LEU LEU H . n 
B 2 24  SER 24  24  24  SER SER H . n 
B 2 25  CYS 25  25  25  CYS CYS H . n 
B 2 26  ALA 26  26  26  ALA ALA H . n 
B 2 27  ALA 27  27  27  ALA ALA H . n 
B 2 28  SER 28  28  28  SER SER H . n 
B 2 29  GLY 29  29  29  GLY GLY H . n 
B 2 30  PHE 30  30  30  PHE PHE H . n 
B 2 31  ASN 31  31  31  ASN ASN H . n 
B 2 32  VAL 32  32  32  VAL VAL H . n 
B 2 33  VAL 33  33  33  VAL VAL H . n 
B 2 34  ASP 34  34  34  ASP ASP H . n 
B 2 35  PHE 35  35  35  PHE PHE H . n 
B 2 36  SER 36  36  36  SER SER H . n 
B 2 37  LEU 37  37  37  LEU LEU H . n 
B 2 38  HIS 38  38  38  HIS HIS H . n 
B 2 39  TRP 39  39  39  TRP TRP H . n 
B 2 40  VAL 40  40  40  VAL VAL H . n 
B 2 41  ARG 41  41  41  ARG ARG H . n 
B 2 42  GLN 42  42  42  GLN GLN H . n 
B 2 43  ALA 43  43  43  ALA ALA H . n 
B 2 44  PRO 44  44  44  PRO PRO H . n 
B 2 45  GLY 45  45  45  GLY GLY H . n 
B 2 46  LYS 46  46  46  LYS LYS H . n 
B 2 47  GLY 47  47  47  GLY GLY H . n 
B 2 48  LEU 48  48  48  LEU LEU H . n 
B 2 49  GLU 49  49  49  GLU GLU H . n 
B 2 50  TRP 50  50  50  TRP TRP H . n 
B 2 51  VAL 51  51  51  VAL VAL H . n 
B 2 52  ALA 52  52  52  ALA ALA H . n 
B 2 53  TYR 53  53  53  TYR TYR H . n 
B 2 54  ILE 54  54  54  ILE ILE H . n 
B 2 55  SER 55  55  55  SER SER H . n 
B 2 56  SER 56  56  56  SER SER H . n 
B 2 57  SER 57  57  57  SER SER H . n 
B 2 58  SER 58  58  58  SER SER H . n 
B 2 59  GLY 59  59  59  GLY GLY H . n 
B 2 60  SER 60  60  60  SER SER H . n 
B 2 61  THR 61  61  61  THR THR H . n 
B 2 62  SER 62  62  62  SER SER H . n 
B 2 63  TYR 63  63  63  TYR TYR H . n 
B 2 64  ALA 64  64  64  ALA ALA H . n 
B 2 65  ASP 65  65  65  ASP ASP H . n 
B 2 66  SER 66  66  66  SER SER H . n 
B 2 67  VAL 67  67  67  VAL VAL H . n 
B 2 68  LYS 68  68  68  LYS LYS H . n 
B 2 69  GLY 69  69  69  GLY GLY H . n 
B 2 70  ARG 70  70  70  ARG ARG H . n 
B 2 71  PHE 71  71  71  PHE PHE H . n 
B 2 72  THR 72  72  72  THR THR H . n 
B 2 73  ILE 73  73  73  ILE ILE H . n 
B 2 74  SER 74  74  74  SER SER H . n 
B 2 75  ALA 75  75  75  ALA ALA H . n 
B 2 76  ASP 76  76  76  ASP ASP H . n 
B 2 77  THR 77  77  77  THR THR H . n 
B 2 78  SER 78  78  78  SER SER H . n 
B 2 79  LYS 79  79  79  LYS LYS H . n 
B 2 80  ASN 80  80  80  ASN ASN H . n 
B 2 81  THR 81  81  81  THR THR H . n 
B 2 82  ALA 82  82  82  ALA ALA H . n 
B 2 83  TYR 83  83  83  TYR TYR H . n 
B 2 84  LEU 84  84  84  LEU LEU H . n 
B 2 85  GLN 85  85  85  GLN GLN H . n 
B 2 86  MET 86  86  86  MET MET H . n 
B 2 87  ASN 87  87  87  ASN ASN H . n 
B 2 88  SER 88  88  88  SER SER H . n 
B 2 89  LEU 89  89  89  LEU LEU H . n 
B 2 90  ARG 90  90  90  ARG ARG H . n 
B 2 91  ALA 91  91  91  ALA ALA H . n 
B 2 92  GLU 92  92  92  GLU GLU H . n 
B 2 93  ASP 93  93  93  ASP ASP H . n 
B 2 94  THR 94  94  94  THR THR H . n 
B 2 95  ALA 95  95  95  ALA ALA H . n 
B 2 96  VAL 96  96  96  VAL VAL H . n 
B 2 97  TYR 97  97  97  TYR TYR H . n 
B 2 98  TYR 98  98  98  TYR TYR H . n 
B 2 99  CYS 99  99  99  CYS CYS H . n 
B 2 100 ALA 100 100 100 ALA ALA H . n 
B 2 101 ARG 101 101 101 ARG ARG H . n 
B 2 102 TRP 102 102 102 TRP TRP H . n 
B 2 103 GLY 103 103 103 GLY GLY H . n 
B 2 104 TYR 104 104 104 TYR TYR H . n 
B 2 105 TRP 105 105 105 TRP TRP H . n 
B 2 106 PRO 106 106 106 PRO PRO H . n 
B 2 107 GLY 107 107 107 GLY GLY H . n 
B 2 108 GLU 108 108 108 GLU GLU H . n 
B 2 109 PRO 109 109 109 PRO PRO H . n 
B 2 110 TRP 110 110 110 TRP TRP H . n 
B 2 111 TRP 111 111 111 TRP TRP H . n 
B 2 112 LYS 112 112 112 LYS LYS H . n 
B 2 113 ALA 113 113 113 ALA ALA H . n 
B 2 114 PHE 114 114 114 PHE PHE H . n 
B 2 115 ASP 115 115 115 ASP ASP H . n 
B 2 116 TYR 116 116 116 TYR TYR H . n 
B 2 117 TRP 117 117 117 TRP TRP H . n 
B 2 118 GLY 118 118 118 GLY GLY H . n 
B 2 119 GLN 119 119 119 GLN GLN H . n 
B 2 120 GLY 120 120 120 GLY GLY H . n 
B 2 121 THR 121 121 121 THR THR H . n 
B 2 122 LEU 122 122 122 LEU LEU H . n 
B 2 123 VAL 123 123 123 VAL VAL H . n 
B 2 124 THR 124 124 124 THR THR H . n 
B 2 125 VAL 125 125 125 VAL VAL H . n 
B 2 126 SER 126 126 126 SER SER H . n 
B 2 127 SER 127 127 127 SER SER H . n 
B 2 128 ALA 128 128 128 ALA ALA H . n 
B 2 129 SER 129 129 129 SER SER H . n 
B 2 130 THR 130 130 130 THR THR H . n 
B 2 131 LYS 131 131 131 LYS LYS H . n 
B 2 132 GLY 132 132 132 GLY GLY H . n 
B 2 133 PRO 133 133 133 PRO PRO H . n 
B 2 134 SER 134 134 134 SER SER H . n 
B 2 135 VAL 135 135 135 VAL VAL H . n 
B 2 136 PHE 136 136 136 PHE PHE H . n 
B 2 137 PRO 137 137 137 PRO PRO H . n 
B 2 138 LEU 138 138 138 LEU LEU H . n 
B 2 139 ALA 139 139 139 ALA ALA H . n 
B 2 140 PRO 140 140 140 PRO PRO H . n 
B 2 141 SER 141 141 141 SER SER H . n 
B 2 142 SER 142 142 142 SER SER H . n 
B 2 143 LYS 143 143 143 LYS LYS H . n 
B 2 144 SER 144 144 144 SER SER H . n 
B 2 145 THR 145 145 145 THR THR H . n 
B 2 146 SER 146 146 146 SER SER H . n 
B 2 147 GLY 147 147 147 GLY GLY H . n 
B 2 148 GLY 148 148 148 GLY GLY H . n 
B 2 149 THR 149 149 149 THR THR H . n 
B 2 150 ALA 150 150 150 ALA ALA H . n 
B 2 151 ALA 151 151 151 ALA ALA H . n 
B 2 152 LEU 152 152 152 LEU LEU H . n 
B 2 153 GLY 153 153 153 GLY GLY H . n 
B 2 154 CYS 154 154 154 CYS CYS H . n 
B 2 155 LEU 155 155 155 LEU LEU H . n 
B 2 156 VAL 156 156 156 VAL VAL H . n 
B 2 157 LYS 157 157 157 LYS LYS H . n 
B 2 158 ASP 158 158 158 ASP ASP H . n 
B 2 159 TYR 159 159 159 TYR TYR H . n 
B 2 160 PHE 160 160 160 PHE PHE H . n 
B 2 161 PRO 161 161 161 PRO PRO H . n 
B 2 162 GLU 162 162 162 GLU GLU H . n 
B 2 163 PRO 163 163 163 PRO PRO H . n 
B 2 164 VAL 164 164 164 VAL VAL H . n 
B 2 165 THR 165 165 165 THR THR H . n 
B 2 166 VAL 166 166 166 VAL VAL H . n 
B 2 167 SER 167 167 167 SER SER H . n 
B 2 168 TRP 168 168 168 TRP TRP H . n 
B 2 169 ASN 169 169 169 ASN ASN H . n 
B 2 170 SER 170 170 170 SER SER H . n 
B 2 171 GLY 171 171 171 GLY GLY H . n 
B 2 172 ALA 172 172 172 ALA ALA H . n 
B 2 173 LEU 173 173 173 LEU LEU H . n 
B 2 174 THR 174 174 174 THR THR H . n 
B 2 175 SER 175 175 175 SER SER H . n 
B 2 176 GLY 176 176 176 GLY GLY H . n 
B 2 177 VAL 177 177 177 VAL VAL H . n 
B 2 178 HIS 178 178 178 HIS HIS H . n 
B 2 179 THR 179 179 179 THR THR H . n 
B 2 180 PHE 180 180 180 PHE PHE H . n 
B 2 181 PRO 181 181 181 PRO PRO H . n 
B 2 182 ALA 182 182 182 ALA ALA H . n 
B 2 183 VAL 183 183 183 VAL VAL H . n 
B 2 184 LEU 184 184 184 LEU LEU H . n 
B 2 185 GLN 185 185 185 GLN GLN H . n 
B 2 186 SER 186 186 186 SER SER H . n 
B 2 187 SER 187 187 187 SER SER H . n 
B 2 188 GLY 188 188 188 GLY GLY H . n 
B 2 189 LEU 189 189 189 LEU LEU H . n 
B 2 190 TYR 190 190 190 TYR TYR H . n 
B 2 191 SER 191 191 191 SER SER H . n 
B 2 192 LEU 192 192 192 LEU LEU H . n 
B 2 193 SER 193 193 193 SER SER H . n 
B 2 194 SER 194 194 194 SER SER H . n 
B 2 195 VAL 195 195 195 VAL VAL H . n 
B 2 196 VAL 196 196 196 VAL VAL H . n 
B 2 197 THR 197 197 197 THR THR H . n 
B 2 198 VAL 198 198 198 VAL VAL H . n 
B 2 199 PRO 199 199 199 PRO PRO H . n 
B 2 200 SER 200 200 200 SER SER H . n 
B 2 201 SER 201 201 201 SER SER H . n 
B 2 202 SER 202 202 202 SER SER H . n 
B 2 203 LEU 203 203 203 LEU LEU H . n 
B 2 204 GLY 204 204 204 GLY GLY H . n 
B 2 205 THR 205 205 205 THR THR H . n 
B 2 206 GLN 206 206 206 GLN GLN H . n 
B 2 207 THR 207 207 207 THR THR H . n 
B 2 208 TYR 208 208 208 TYR TYR H . n 
B 2 209 ILE 209 209 209 ILE ILE H . n 
B 2 210 CYS 210 210 210 CYS CYS H . n 
B 2 211 ASN 211 211 211 ASN ASN H . n 
B 2 212 VAL 212 212 212 VAL VAL H . n 
B 2 213 ASN 213 213 213 ASN ASN H . n 
B 2 214 HIS 214 214 214 HIS HIS H . n 
B 2 215 LYS 215 215 215 LYS LYS H . n 
B 2 216 PRO 216 216 216 PRO PRO H . n 
B 2 217 SER 217 217 217 SER SER H . n 
B 2 218 ASN 218 218 218 ASN ASN H . n 
B 2 219 THR 219 219 219 THR THR H . n 
B 2 220 LYS 220 220 220 LYS LYS H . n 
B 2 221 VAL 221 221 221 VAL VAL H . n 
B 2 222 ASP 222 222 222 ASP ASP H . n 
B 2 223 LYS 223 223 223 LYS LYS H . n 
B 2 224 LYS 224 224 224 LYS LYS H . n 
B 2 225 VAL 225 225 225 VAL VAL H . n 
B 2 226 GLU 226 226 226 GLU GLU H . n 
B 2 227 PRO 227 227 227 PRO PRO H . n 
B 2 228 LYS 228 228 228 LYS LYS H . n 
B 2 229 SER 229 229 ?   ?   ?   H . n 
B 2 230 CYS 230 230 ?   ?   ?   H . n 
B 2 231 ASP 231 231 ?   ?   ?   H . n 
C 3 1   ALA 1   -5  ?   ?   ?   K . n 
C 3 2   GLN 2   -4  ?   ?   ?   K . n 
C 3 3   PRO 3   -3  ?   ?   ?   K . n 
C 3 4   ALA 4   -2  ?   ?   ?   K . n 
C 3 5   MET 5   -1  ?   ?   ?   K . n 
C 3 6   ALA 6   0   ?   ?   ?   K . n 
C 3 7   GLN 7   1   1   GLN GLN K . n 
C 3 8   VAL 8   2   2   VAL VAL K . n 
C 3 9   GLN 9   3   3   GLN GLN K . n 
C 3 10  LEU 10  4   4   LEU LEU K . n 
C 3 11  GLN 11  5   5   GLN GLN K . n 
C 3 12  GLU 12  6   6   GLU GLU K . n 
C 3 13  SER 13  7   7   SER SER K . n 
C 3 14  GLY 14  8   8   GLY GLY K . n 
C 3 15  GLY 15  9   9   GLY GLY K . n 
C 3 16  GLY 16  10  10  GLY GLY K . n 
C 3 17  LEU 17  11  11  LEU LEU K . n 
C 3 18  VAL 18  12  12  VAL VAL K . n 
C 3 19  GLN 19  13  13  GLN GLN K . n 
C 3 20  PRO 20  14  14  PRO PRO K . n 
C 3 21  GLY 21  15  15  GLY GLY K . n 
C 3 22  GLY 22  16  16  GLY GLY K . n 
C 3 23  SER 23  17  17  SER SER K . n 
C 3 24  LEU 24  18  18  LEU LEU K . n 
C 3 25  ARG 25  19  19  ARG ARG K . n 
C 3 26  LEU 26  20  20  LEU LEU K . n 
C 3 27  SER 27  21  21  SER SER K . n 
C 3 28  CYS 28  22  22  CYS CYS K . n 
C 3 29  ALA 29  23  23  ALA ALA K . n 
C 3 30  ALA 30  24  24  ALA ALA K . n 
C 3 31  SER 31  25  25  SER SER K . n 
C 3 32  GLY 32  26  26  GLY GLY K . n 
C 3 33  ARG 33  27  27  ARG ARG K . n 
C 3 34  THR 34  28  28  THR THR K . n 
C 3 35  ILE 35  29  29  ILE ILE K . n 
C 3 36  SER 36  30  30  SER SER K . n 
C 3 37  ARG 37  31  31  ARG ARG K . n 
C 3 38  TYR 38  32  32  TYR TYR K . n 
C 3 39  ALA 39  33  33  ALA ALA K . n 
C 3 40  MET 40  34  34  MET MET K . n 
C 3 41  SER 41  35  35  SER SER K . n 
C 3 42  TRP 42  36  36  TRP TRP K . n 
C 3 43  PHE 43  37  37  PHE PHE K . n 
C 3 44  ARG 44  38  38  ARG ARG K . n 
C 3 45  GLN 45  39  39  GLN GLN K . n 
C 3 46  ALA 46  40  40  ALA ALA K . n 
C 3 47  PRO 47  41  41  PRO PRO K . n 
C 3 48  GLY 48  42  42  GLY GLY K . n 
C 3 49  LYS 49  43  43  LYS LYS K . n 
C 3 50  GLU 50  44  44  GLU GLU K . n 
C 3 51  ARG 51  45  45  ARG ARG K . n 
C 3 52  GLU 52  46  46  GLU GLU K . n 
C 3 53  PHE 53  47  47  PHE PHE K . n 
C 3 54  VAL 54  48  48  VAL VAL K . n 
C 3 55  ALA 55  49  49  ALA ALA K . n 
C 3 56  VAL 56  50  50  VAL VAL K . n 
C 3 57  ALA 57  51  51  ALA ALA K . n 
C 3 58  ARG 58  52  52  ARG ARG K . n 
C 3 59  ARG 59  53  53  ARG ARG K . n 
C 3 60  SER 60  54  54  SER SER K . n 
C 3 61  GLY 61  55  55  GLY GLY K . n 
C 3 62  ASP 62  56  56  ASP ASP K . n 
C 3 63  GLY 63  57  57  GLY GLY K . n 
C 3 64  ALA 64  58  58  ALA ALA K . n 
C 3 65  PHE 65  59  59  PHE PHE K . n 
C 3 66  TYR 66  60  60  TYR TYR K . n 
C 3 67  ALA 67  61  61  ALA ALA K . n 
C 3 68  ASP 68  62  62  ASP ASP K . n 
C 3 69  SER 69  63  63  SER SER K . n 
C 3 70  VAL 70  64  64  VAL VAL K . n 
C 3 71  GLN 71  65  65  GLN GLN K . n 
C 3 72  GLY 72  66  66  GLY GLY K . n 
C 3 73  ARG 73  67  67  ARG ARG K . n 
C 3 74  PHE 74  68  68  PHE PHE K . n 
C 3 75  THR 75  69  69  THR THR K . n 
C 3 76  VAL 76  70  70  VAL VAL K . n 
C 3 77  SER 77  71  71  SER SER K . n 
C 3 78  ARG 78  72  72  ARG ARG K . n 
C 3 79  ASP 79  73  73  ASP ASP K . n 
C 3 80  ASP 80  74  74  ASP ASP K . n 
C 3 81  ALA 81  75  75  ALA ALA K . n 
C 3 82  LYS 82  76  76  LYS LYS K . n 
C 3 83  ASN 83  77  77  ASN ASN K . n 
C 3 84  THR 84  78  78  THR THR K . n 
C 3 85  VAL 85  79  79  VAL VAL K . n 
C 3 86  TYR 86  80  80  TYR TYR K . n 
C 3 87  LEU 87  81  81  LEU LEU K . n 
C 3 88  GLN 88  82  82  GLN GLN K . n 
C 3 89  MET 89  83  83  MET MET K . n 
C 3 90  ASN 90  84  84  ASN ASN K . n 
C 3 91  SER 91  85  85  SER SER K . n 
C 3 92  LEU 92  86  86  LEU LEU K . n 
C 3 93  LYS 93  87  87  LYS LYS K . n 
C 3 94  PRO 94  88  88  PRO PRO K . n 
C 3 95  GLU 95  89  89  GLU GLU K . n 
C 3 96  ASP 96  90  90  ASP ASP K . n 
C 3 97  THR 97  91  91  THR THR K . n 
C 3 98  ALA 98  92  92  ALA ALA K . n 
C 3 99  VAL 99  93  93  VAL VAL K . n 
C 3 100 TYR 100 94  94  TYR TYR K . n 
C 3 101 TYR 101 95  95  TYR TYR K . n 
C 3 102 CYS 102 96  96  CYS CYS K . n 
C 3 103 ALA 103 97  97  ALA ALA K . n 
C 3 104 ILE 104 98  98  ILE ILE K . n 
C 3 105 ASP 105 99  99  ASP ASP K . n 
C 3 106 SER 106 100 100 SER SER K . n 
C 3 107 ASP 107 101 101 ASP ASP K . n 
C 3 108 THR 108 102 102 THR THR K . n 
C 3 109 PHE 109 103 103 PHE PHE K . n 
C 3 110 TYR 110 104 104 TYR TYR K . n 
C 3 111 SER 111 105 105 SER SER K . n 
C 3 112 GLY 112 106 106 GLY GLY K . n 
C 3 113 SER 113 107 107 SER SER K . n 
C 3 114 TYR 114 108 108 TYR TYR K . n 
C 3 115 ASP 115 109 109 ASP ASP K . n 
C 3 116 TYR 116 110 110 TYR TYR K . n 
C 3 117 TRP 117 111 111 TRP TRP K . n 
C 3 118 GLY 118 112 112 GLY GLY K . n 
C 3 119 GLN 119 113 113 GLN GLN K . n 
C 3 120 GLY 120 114 114 GLY GLY K . n 
C 3 121 THR 121 115 115 THR THR K . n 
C 3 122 GLN 122 116 116 GLN GLN K . n 
C 3 123 VAL 123 117 117 VAL VAL K . n 
C 3 124 THR 124 118 118 THR THR K . n 
C 3 125 VAL 125 119 119 VAL VAL K . n 
C 3 126 SER 126 120 120 SER SER K . n 
C 3 127 SER 127 121 ?   ?   ?   K . n 
C 3 128 LEU 128 122 ?   ?   ?   K . n 
C 3 129 GLU 129 123 ?   ?   ?   K . n 
C 3 130 ASP 130 124 ?   ?   ?   K . n 
C 3 131 TYR 131 125 ?   ?   ?   K . n 
C 3 132 LYS 132 126 ?   ?   ?   K . n 
C 3 133 ASP 133 127 ?   ?   ?   K . n 
C 3 134 ASP 134 128 ?   ?   ?   K . n 
C 3 135 LYS 135 129 ?   ?   ?   K . n 
C 3 136 HIS 136 130 ?   ?   ?   K . n 
C 3 137 HIS 137 131 ?   ?   ?   K . n 
C 3 138 HIS 138 132 ?   ?   ?   K . n 
C 3 139 HIS 139 133 ?   ?   ?   K . n 
C 3 140 HIS 140 134 ?   ?   ?   K . n 
C 3 141 HIS 141 135 ?   ?   ?   K . n 
D 4 1   ASP 1   2   2   ASP ASP L . n 
D 4 2   ILE 2   3   3   ILE ILE L . n 
D 4 3   GLN 3   4   4   GLN GLN L . n 
D 4 4   MET 4   5   5   MET MET L . n 
D 4 5   THR 5   6   6   THR THR L . n 
D 4 6   GLN 6   7   7   GLN GLN L . n 
D 4 7   SER 7   8   8   SER SER L . n 
D 4 8   PRO 8   9   9   PRO PRO L . n 
D 4 9   SER 9   10  10  SER SER L . n 
D 4 10  SER 10  11  11  SER SER L . n 
D 4 11  LEU 11  12  12  LEU LEU L . n 
D 4 12  SER 12  13  13  SER SER L . n 
D 4 13  ALA 13  14  14  ALA ALA L . n 
D 4 14  SER 14  15  15  SER SER L . n 
D 4 15  VAL 15  16  16  VAL VAL L . n 
D 4 16  GLY 16  17  17  GLY GLY L . n 
D 4 17  ASP 17  18  18  ASP ASP L . n 
D 4 18  ARG 18  19  19  ARG ARG L . n 
D 4 19  VAL 19  20  20  VAL VAL L . n 
D 4 20  THR 20  21  21  THR THR L . n 
D 4 21  ILE 21  22  22  ILE ILE L . n 
D 4 22  THR 22  23  23  THR THR L . n 
D 4 23  CYS 23  24  24  CYS CYS L . n 
D 4 24  ARG 24  25  25  ARG ARG L . n 
D 4 25  ALA 25  26  26  ALA ALA L . n 
D 4 26  SER 26  27  27  SER SER L . n 
D 4 27  GLN 27  28  28  GLN GLN L . n 
D 4 28  SER 28  29  29  SER SER L . n 
D 4 29  VAL 29  30  30  VAL VAL L . n 
D 4 30  SER 30  31  31  SER SER L . n 
D 4 31  SER 31  32  32  SER SER L . n 
D 4 32  ALA 32  33  33  ALA ALA L . n 
D 4 33  VAL 33  34  34  VAL VAL L . n 
D 4 34  ALA 34  35  35  ALA ALA L . n 
D 4 35  TRP 35  36  36  TRP TRP L . n 
D 4 36  TYR 36  37  37  TYR TYR L . n 
D 4 37  GLN 37  38  38  GLN GLN L . n 
D 4 38  GLN 38  39  39  GLN GLN L . n 
D 4 39  LYS 39  40  40  LYS LYS L . n 
D 4 40  PRO 40  41  41  PRO PRO L . n 
D 4 41  GLY 41  42  42  GLY GLY L . n 
D 4 42  LYS 42  43  43  LYS LYS L . n 
D 4 43  ALA 43  44  44  ALA ALA L . n 
D 4 44  PRO 44  45  45  PRO PRO L . n 
D 4 45  LYS 45  46  46  LYS LYS L . n 
D 4 46  LEU 46  47  47  LEU LEU L . n 
D 4 47  LEU 47  48  48  LEU LEU L . n 
D 4 48  ILE 48  49  49  ILE ILE L . n 
D 4 49  TYR 49  50  50  TYR TYR L . n 
D 4 50  SER 50  51  51  SER SER L . n 
D 4 51  ALA 51  52  52  ALA ALA L . n 
D 4 52  SER 52  53  53  SER SER L . n 
D 4 53  SER 53  54  54  SER SER L . n 
D 4 54  LEU 54  55  55  LEU LEU L . n 
D 4 55  TYR 55  56  56  TYR TYR L . n 
D 4 56  SER 56  57  57  SER SER L . n 
D 4 57  GLY 57  58  58  GLY GLY L . n 
D 4 58  VAL 58  59  59  VAL VAL L . n 
D 4 59  PRO 59  60  60  PRO PRO L . n 
D 4 60  SER 60  61  61  SER SER L . n 
D 4 61  ARG 61  62  62  ARG ARG L . n 
D 4 62  PHE 62  63  63  PHE PHE L . n 
D 4 63  SER 63  64  64  SER SER L . n 
D 4 64  GLY 64  65  65  GLY GLY L . n 
D 4 65  SER 65  66  66  SER SER L . n 
D 4 66  ARG 66  67  67  ARG ARG L . n 
D 4 67  SER 67  68  68  SER SER L . n 
D 4 68  GLY 68  69  69  GLY GLY L . n 
D 4 69  THR 69  70  70  THR THR L . n 
D 4 70  ASP 70  71  71  ASP ASP L . n 
D 4 71  PHE 71  72  72  PHE PHE L . n 
D 4 72  THR 72  73  73  THR THR L . n 
D 4 73  LEU 73  74  74  LEU LEU L . n 
D 4 74  THR 74  75  75  THR THR L . n 
D 4 75  ILE 75  76  76  ILE ILE L . n 
D 4 76  SER 76  77  77  SER SER L . n 
D 4 77  SER 77  78  78  SER SER L . n 
D 4 78  LEU 78  79  79  LEU LEU L . n 
D 4 79  GLN 79  80  80  GLN GLN L . n 
D 4 80  PRO 80  81  81  PRO PRO L . n 
D 4 81  GLU 81  82  82  GLU GLU L . n 
D 4 82  ASP 82  83  83  ASP ASP L . n 
D 4 83  PHE 83  84  84  PHE PHE L . n 
D 4 84  ALA 84  85  85  ALA ALA L . n 
D 4 85  THR 85  86  86  THR THR L . n 
D 4 86  TYR 86  87  87  TYR TYR L . n 
D 4 87  TYR 87  88  88  TYR TYR L . n 
D 4 88  CYS 88  89  89  CYS CYS L . n 
D 4 89  GLN 89  90  90  GLN GLN L . n 
D 4 90  GLN 90  91  91  GLN GLN L . n 
D 4 91  TYR 91  92  92  TYR TYR L . n 
D 4 92  LEU 92  93  93  LEU LEU L . n 
D 4 93  TYR 93  94  94  TYR TYR L . n 
D 4 94  TYR 94  95  95  TYR TYR L . n 
D 4 95  SER 95  96  96  SER SER L . n 
D 4 96  LEU 96  97  97  LEU LEU L . n 
D 4 97  VAL 97  98  98  VAL VAL L . n 
D 4 98  THR 98  99  99  THR THR L . n 
D 4 99  PHE 99  100 100 PHE PHE L . n 
D 4 100 GLY 100 101 101 GLY GLY L . n 
D 4 101 GLN 101 102 102 GLN GLN L . n 
D 4 102 GLY 102 103 103 GLY GLY L . n 
D 4 103 THR 103 104 104 THR THR L . n 
D 4 104 LYS 104 105 105 LYS LYS L . n 
D 4 105 VAL 105 106 106 VAL VAL L . n 
D 4 106 GLU 106 107 107 GLU GLU L . n 
D 4 107 ILE 107 108 108 ILE ILE L . n 
D 4 108 LYS 108 109 109 LYS LYS L . n 
D 4 109 ARG 109 110 110 ARG ARG L . n 
D 4 110 THR 110 111 111 THR THR L . n 
D 4 111 VAL 111 112 112 VAL VAL L . n 
D 4 112 ALA 112 113 113 ALA ALA L . n 
D 4 113 ALA 113 114 114 ALA ALA L . n 
D 4 114 PRO 114 115 115 PRO PRO L . n 
D 4 115 SER 115 116 116 SER SER L . n 
D 4 116 VAL 116 117 117 VAL VAL L . n 
D 4 117 PHE 117 118 118 PHE PHE L . n 
D 4 118 ILE 118 119 119 ILE ILE L . n 
D 4 119 PHE 119 120 120 PHE PHE L . n 
D 4 120 PRO 120 121 121 PRO PRO L . n 
D 4 121 PRO 121 122 122 PRO PRO L . n 
D 4 122 SER 122 123 123 SER SER L . n 
D 4 123 ASP 123 124 124 ASP ASP L . n 
D 4 124 GLU 124 125 125 GLU GLU L . n 
D 4 125 GLN 125 126 126 GLN GLN L . n 
D 4 126 LEU 126 127 127 LEU LEU L . n 
D 4 127 LYS 127 128 128 LYS LYS L . n 
D 4 128 SER 128 129 129 SER SER L . n 
D 4 129 GLY 129 130 130 GLY GLY L . n 
D 4 130 THR 130 131 131 THR THR L . n 
D 4 131 ALA 131 132 132 ALA ALA L . n 
D 4 132 SER 132 133 133 SER SER L . n 
D 4 133 VAL 133 134 134 VAL VAL L . n 
D 4 134 VAL 134 135 135 VAL VAL L . n 
D 4 135 CYS 135 136 136 CYS CYS L . n 
D 4 136 LEU 136 137 137 LEU LEU L . n 
D 4 137 LEU 137 138 138 LEU LEU L . n 
D 4 138 ASN 138 139 139 ASN ASN L . n 
D 4 139 ASN 139 140 140 ASN ASN L . n 
D 4 140 PHE 140 141 141 PHE PHE L . n 
D 4 141 TYR 141 142 142 TYR TYR L . n 
D 4 142 PRO 142 143 143 PRO PRO L . n 
D 4 143 ARG 143 144 144 ARG ARG L . n 
D 4 144 GLU 144 145 145 GLU GLU L . n 
D 4 145 ALA 145 146 146 ALA ALA L . n 
D 4 146 LYS 146 147 147 LYS LYS L . n 
D 4 147 VAL 147 148 148 VAL VAL L . n 
D 4 148 GLN 148 149 149 GLN GLN L . n 
D 4 149 TRP 149 150 150 TRP TRP L . n 
D 4 150 LYS 150 151 151 LYS LYS L . n 
D 4 151 VAL 151 152 152 VAL VAL L . n 
D 4 152 ASP 152 153 153 ASP ASP L . n 
D 4 153 ASN 153 154 154 ASN ASN L . n 
D 4 154 ALA 154 155 155 ALA ALA L . n 
D 4 155 LEU 155 156 156 LEU LEU L . n 
D 4 156 GLN 156 157 157 GLN GLN L . n 
D 4 157 SER 157 158 158 SER SER L . n 
D 4 158 GLY 158 159 159 GLY GLY L . n 
D 4 159 ASN 159 160 160 ASN ASN L . n 
D 4 160 SER 160 161 161 SER SER L . n 
D 4 161 GLN 161 162 162 GLN GLN L . n 
D 4 162 GLU 162 163 163 GLU GLU L . n 
D 4 163 SER 163 164 164 SER SER L . n 
D 4 164 VAL 164 165 165 VAL VAL L . n 
D 4 165 THR 165 166 166 THR THR L . n 
D 4 166 GLU 166 167 167 GLU GLU L . n 
D 4 167 GLN 167 168 168 GLN GLN L . n 
D 4 168 ASP 168 169 169 ASP ASP L . n 
D 4 169 SER 169 170 170 SER SER L . n 
D 4 170 LYS 170 171 171 LYS LYS L . n 
D 4 171 ASP 171 172 172 ASP ASP L . n 
D 4 172 SER 172 173 173 SER SER L . n 
D 4 173 THR 173 174 174 THR THR L . n 
D 4 174 TYR 174 175 175 TYR TYR L . n 
D 4 175 SER 175 176 176 SER SER L . n 
D 4 176 LEU 176 177 177 LEU LEU L . n 
D 4 177 SER 177 178 178 SER SER L . n 
D 4 178 SER 178 179 179 SER SER L . n 
D 4 179 THR 179 180 180 THR THR L . n 
D 4 180 LEU 180 181 181 LEU LEU L . n 
D 4 181 THR 181 182 182 THR THR L . n 
D 4 182 LEU 182 183 183 LEU LEU L . n 
D 4 183 SER 183 184 184 SER SER L . n 
D 4 184 LYS 184 185 185 LYS LYS L . n 
D 4 185 ALA 185 186 186 ALA ALA L . n 
D 4 186 ASP 186 187 187 ASP ASP L . n 
D 4 187 TYR 187 188 188 TYR TYR L . n 
D 4 188 GLU 188 189 189 GLU GLU L . n 
D 4 189 LYS 189 190 190 LYS LYS L . n 
D 4 190 HIS 190 191 191 HIS HIS L . n 
D 4 191 LYS 191 192 192 LYS LYS L . n 
D 4 192 VAL 192 193 193 VAL VAL L . n 
D 4 193 TYR 193 194 194 TYR TYR L . n 
D 4 194 ALA 194 195 195 ALA ALA L . n 
D 4 195 CYS 195 196 196 CYS CYS L . n 
D 4 196 GLU 196 197 197 GLU GLU L . n 
D 4 197 VAL 197 198 198 VAL VAL L . n 
D 4 198 THR 198 199 199 THR THR L . n 
D 4 199 HIS 199 200 200 HIS HIS L . n 
D 4 200 GLN 200 201 201 GLN GLN L . n 
D 4 201 GLY 201 202 202 GLY GLY L . n 
D 4 202 LEU 202 203 203 LEU LEU L . n 
D 4 203 SER 203 204 204 SER SER L . n 
D 4 204 SER 204 205 205 SER SER L . n 
D 4 205 PRO 205 206 206 PRO PRO L . n 
D 4 206 VAL 206 207 207 VAL VAL L . n 
D 4 207 THR 207 208 208 THR THR L . n 
D 4 208 LYS 208 209 209 LYS LYS L . n 
D 4 209 SER 209 210 210 SER SER L . n 
D 4 210 PHE 210 211 211 PHE PHE L . n 
D 4 211 ASN 211 212 212 ASN ASN L . n 
D 4 212 ARG 212 213 213 ARG ARG L . n 
D 4 213 GLY 213 214 ?   ?   ?   L . n 
D 4 214 GLU 214 215 ?   ?   ?   L . n 
D 4 215 CYS 215 216 ?   ?   ?   L . n 
E 5 1   MET 1   -63 ?   ?   ?   R . n 
E 5 2   LYS 2   -62 ?   ?   ?   R . n 
E 5 3   THR 3   -61 ?   ?   ?   R . n 
E 5 4   ILE 4   -60 ?   ?   ?   R . n 
E 5 5   ILE 5   -59 ?   ?   ?   R . n 
E 5 6   ALA 6   -58 ?   ?   ?   R . n 
E 5 7   LEU 7   -57 ?   ?   ?   R . n 
E 5 8   SER 8   -56 ?   ?   ?   R . n 
E 5 9   TYR 9   -55 ?   ?   ?   R . n 
E 5 10  ILE 10  -54 ?   ?   ?   R . n 
E 5 11  PHE 11  -53 ?   ?   ?   R . n 
E 5 12  CYS 12  -52 ?   ?   ?   R . n 
E 5 13  LEU 13  -51 ?   ?   ?   R . n 
E 5 14  VAL 14  -50 ?   ?   ?   R . n 
E 5 15  PHE 15  -49 ?   ?   ?   R . n 
E 5 16  ALA 16  -48 ?   ?   ?   R . n 
E 5 17  ASP 17  -47 ?   ?   ?   R . n 
E 5 18  TYR 18  -46 ?   ?   ?   R . n 
E 5 19  LYS 19  -45 ?   ?   ?   R . n 
E 5 20  ASP 20  -44 ?   ?   ?   R . n 
E 5 21  ASP 21  -43 ?   ?   ?   R . n 
E 5 22  ASP 22  -42 ?   ?   ?   R . n 
E 5 23  ASP 23  -41 ?   ?   ?   R . n 
E 5 24  ALA 24  -40 ?   ?   ?   R . n 
E 5 25  TRP 25  -39 ?   ?   ?   R . n 
E 5 26  SER 26  -38 ?   ?   ?   R . n 
E 5 27  HIS 27  -37 ?   ?   ?   R . n 
E 5 28  PRO 28  -36 ?   ?   ?   R . n 
E 5 29  GLN 29  -35 ?   ?   ?   R . n 
E 5 30  PHE 30  -34 ?   ?   ?   R . n 
E 5 31  GLU 31  -33 ?   ?   ?   R . n 
E 5 32  LYS 32  -32 ?   ?   ?   R . n 
E 5 33  GLY 33  -31 ?   ?   ?   R . n 
E 5 34  GLY 34  -30 ?   ?   ?   R . n 
E 5 35  GLY 35  -29 ?   ?   ?   R . n 
E 5 36  SER 36  -28 ?   ?   ?   R . n 
E 5 37  GLY 37  -27 ?   ?   ?   R . n 
E 5 38  GLY 38  -26 ?   ?   ?   R . n 
E 5 39  GLY 39  -25 ?   ?   ?   R . n 
E 5 40  SER 40  -24 ?   ?   ?   R . n 
E 5 41  GLY 41  -23 ?   ?   ?   R . n 
E 5 42  GLY 42  -22 ?   ?   ?   R . n 
E 5 43  GLY 43  -21 ?   ?   ?   R . n 
E 5 44  SER 44  -20 ?   ?   ?   R . n 
E 5 45  TRP 45  -19 ?   ?   ?   R . n 
E 5 46  SER 46  -18 ?   ?   ?   R . n 
E 5 47  HIS 47  -17 ?   ?   ?   R . n 
E 5 48  PRO 48  -16 ?   ?   ?   R . n 
E 5 49  GLN 49  -15 ?   ?   ?   R . n 
E 5 50  PHE 50  -14 ?   ?   ?   R . n 
E 5 51  GLU 51  -13 ?   ?   ?   R . n 
E 5 52  LYS 52  -12 ?   ?   ?   R . n 
E 5 53  LEU 53  -11 ?   ?   ?   R . n 
E 5 54  GLU 54  -10 ?   ?   ?   R . n 
E 5 55  VAL 55  -9  ?   ?   ?   R . n 
E 5 56  LEU 56  -8  ?   ?   ?   R . n 
E 5 57  GLN 57  -7  ?   ?   ?   R . n 
E 5 58  GLY 58  -6  ?   ?   ?   R . n 
E 5 59  PRO 59  -5  ?   ?   ?   R . n 
E 5 60  ASP 60  -4  ?   ?   ?   R . n 
E 5 61  TYR 61  -3  ?   ?   ?   R . n 
E 5 62  LYS 62  -2  ?   ?   ?   R . n 
E 5 63  ASP 63  -1  ?   ?   ?   R . n 
E 5 64  ASP 64  0   ?   ?   ?   R . n 
E 5 65  ASP 65  1   ?   ?   ?   R . n 
E 5 66  ASP 66  2   ?   ?   ?   R . n 
E 5 67  ALA 67  3   ?   ?   ?   R . n 
E 5 68  ALA 68  4   ?   ?   ?   R . n 
E 5 69  SER 69  5   ?   ?   ?   R . n 
E 5 70  THR 70  6   ?   ?   ?   R . n 
E 5 71  THR 71  7   ?   ?   ?   R . n 
E 5 72  SER 72  8   ?   ?   ?   R . n 
E 5 73  ALA 73  9   ?   ?   ?   R . n 
E 5 74  VAL 74  10  ?   ?   ?   R . n 
E 5 75  PRO 75  11  ?   ?   ?   R . n 
E 5 76  GLY 76  12  ?   ?   ?   R . n 
E 5 77  HIS 77  13  ?   ?   ?   R . n 
E 5 78  PRO 78  14  ?   ?   ?   R . n 
E 5 79  SER 79  15  ?   ?   ?   R . n 
E 5 80  LEU 80  16  ?   ?   ?   R . n 
E 5 81  PRO 81  17  ?   ?   ?   R . n 
E 5 82  SER 82  18  ?   ?   ?   R . n 
E 5 83  LEU 83  19  ?   ?   ?   R . n 
E 5 84  PRO 84  20  ?   ?   ?   R . n 
E 5 85  SER 85  21  ?   ?   ?   R . n 
E 5 86  GLN 86  22  ?   ?   ?   R . n 
E 5 87  SER 87  23  ?   ?   ?   R . n 
E 5 88  SER 88  24  ?   ?   ?   R . n 
E 5 89  GLN 89  25  ?   ?   ?   R . n 
E 5 90  GLU 90  26  ?   ?   ?   R . n 
E 5 91  ARG 91  27  ?   ?   ?   R . n 
E 5 92  PRO 92  28  ?   ?   ?   R . n 
E 5 93  LEU 93  29  ?   ?   ?   R . n 
E 5 94  ASP 94  30  ?   ?   ?   R . n 
E 5 95  THR 95  31  ?   ?   ?   R . n 
E 5 96  ARG 96  32  ?   ?   ?   R . n 
E 5 97  ASP 97  33  ?   ?   ?   R . n 
E 5 98  PRO 98  34  ?   ?   ?   R . n 
E 5 99  LEU 99  35  35  LEU LEU R . n 
E 5 100 LEU 100 36  36  LEU LEU R . n 
E 5 101 ALA 101 37  37  ALA ALA R . n 
E 5 102 ARG 102 38  38  ARG ARG R . n 
E 5 103 ALA 103 39  39  ALA ALA R . n 
E 5 104 GLU 104 40  40  GLU GLU R . n 
E 5 105 LEU 105 41  41  LEU LEU R . n 
E 5 106 ALA 106 42  42  ALA ALA R . n 
E 5 107 LEU 107 43  43  LEU LEU R . n 
E 5 108 LEU 108 44  44  LEU LEU R . n 
E 5 109 SER 109 45  45  SER SER R . n 
E 5 110 ILE 110 46  46  ILE ILE R . n 
E 5 111 VAL 111 47  47  VAL VAL R . n 
E 5 112 PHE 112 48  48  PHE PHE R . n 
E 5 113 VAL 113 49  49  VAL VAL R . n 
E 5 114 ALA 114 50  50  ALA ALA R . n 
E 5 115 VAL 115 51  51  VAL VAL R . n 
E 5 116 ALA 116 52  52  ALA ALA R . n 
E 5 117 LEU 117 53  53  LEU LEU R . n 
E 5 118 SER 118 54  54  SER SER R . n 
E 5 119 ASN 119 55  55  ASN ASN R . n 
E 5 120 GLY 120 56  56  GLY GLY R . n 
E 5 121 LEU 121 57  57  LEU LEU R . n 
E 5 122 VAL 122 58  58  VAL VAL R . n 
E 5 123 LEU 123 59  59  LEU LEU R . n 
E 5 124 ALA 124 60  60  ALA ALA R . n 
E 5 125 ALA 125 61  61  ALA ALA R . n 
E 5 126 LEU 126 62  62  LEU LEU R . n 
E 5 127 ALA 127 63  63  ALA ALA R . n 
E 5 128 ARG 128 64  64  ARG ARG R . n 
E 5 129 ARG 129 65  65  ARG ARG R . n 
E 5 130 GLY 130 66  66  GLY GLY R . n 
E 5 131 ARG 131 67  67  ARG ARG R . n 
E 5 132 ARG 132 68  68  ARG ARG R . n 
E 5 133 GLY 133 69  69  GLY GLY R . n 
E 5 134 HIS 134 70  70  HIS HIS R . n 
E 5 135 TRP 135 71  71  TRP TRP R . n 
E 5 136 ALA 136 72  72  ALA ALA R . n 
E 5 137 PRO 137 73  73  PRO PRO R . n 
E 5 138 ILE 138 74  74  ILE ILE R . n 
E 5 139 HIS 139 75  75  HIS HIS R . n 
E 5 140 VAL 140 76  76  VAL VAL R . n 
E 5 141 PHE 141 77  77  PHE PHE R . n 
E 5 142 ILE 142 78  78  ILE ILE R . n 
E 5 143 GLY 143 79  79  GLY GLY R . n 
E 5 144 HIS 144 80  80  HIS HIS R . n 
E 5 145 LEU 145 81  81  LEU LEU R . n 
E 5 146 CYS 146 82  82  CYS CYS R . n 
E 5 147 LEU 147 83  83  LEU LEU R . n 
E 5 148 ALA 148 84  84  ALA ALA R . n 
E 5 149 ASP 149 85  85  ASP ASP R . n 
E 5 150 LEU 150 86  86  LEU LEU R . n 
E 5 151 ALA 151 87  87  ALA ALA R . n 
E 5 152 VAL 152 88  88  VAL VAL R . n 
E 5 153 ALA 153 89  89  ALA ALA R . n 
E 5 154 LEU 154 90  90  LEU LEU R . n 
E 5 155 PHE 155 91  91  PHE PHE R . n 
E 5 156 GLN 156 92  92  GLN GLN R . n 
E 5 157 VAL 157 93  93  VAL VAL R . n 
E 5 158 LEU 158 94  94  LEU LEU R . n 
E 5 159 PRO 159 95  95  PRO PRO R . n 
E 5 160 GLN 160 96  96  GLN GLN R . n 
E 5 161 LEU 161 97  97  LEU LEU R . n 
E 5 162 ALA 162 98  98  ALA ALA R . n 
E 5 163 TRP 163 99  99  TRP TRP R . n 
E 5 164 LYS 164 100 100 LYS LYS R . n 
E 5 165 ALA 165 101 101 ALA ALA R . n 
E 5 166 THR 166 102 102 THR THR R . n 
E 5 167 ASP 167 103 103 ASP ASP R . n 
E 5 168 ARG 168 104 104 ARG ARG R . n 
E 5 169 PHE 169 105 105 PHE PHE R . n 
E 5 170 ARG 170 106 106 ARG ARG R . n 
E 5 171 GLY 171 107 107 GLY GLY R . n 
E 5 172 PRO 172 108 ?   ?   ?   R . n 
E 5 173 ASP 173 109 109 ASP ASP R . n 
E 5 174 ALA 174 110 110 ALA ALA R . n 
E 5 175 LEU 175 111 111 LEU LEU R . n 
E 5 176 CYS 176 112 112 CYS CYS R . n 
E 5 177 ARG 177 113 113 ARG ARG R . n 
E 5 178 ALA 178 114 114 ALA ALA R . n 
E 5 179 VAL 179 115 115 VAL VAL R . n 
E 5 180 LYS 180 116 116 LYS LYS R . n 
E 5 181 TYR 181 117 117 TYR TYR R . n 
E 5 182 LEU 182 118 118 LEU LEU R . n 
E 5 183 GLN 183 119 119 GLN GLN R . n 
E 5 184 MET 184 120 120 MET MET R . n 
E 5 185 VAL 185 121 121 VAL VAL R . n 
E 5 186 GLY 186 122 122 GLY GLY R . n 
E 5 187 MET 187 123 123 MET MET R . n 
E 5 188 TYR 188 124 124 TYR TYR R . n 
E 5 189 ALA 189 125 125 ALA ALA R . n 
E 5 190 SER 190 126 126 SER SER R . n 
E 5 191 SER 191 127 127 SER SER R . n 
E 5 192 TYR 192 128 128 TYR TYR R . n 
E 5 193 MET 193 129 129 MET MET R . n 
E 5 194 ILE 194 130 130 ILE ILE R . n 
E 5 195 LEU 195 131 131 LEU LEU R . n 
E 5 196 ALA 196 132 132 ALA ALA R . n 
E 5 197 MET 197 133 133 MET MET R . n 
E 5 198 THR 198 134 134 THR THR R . n 
E 5 199 LEU 199 135 135 LEU LEU R . n 
E 5 200 ASP 200 136 136 ASP ASP R . n 
E 5 201 ARG 201 137 137 ARG ARG R . n 
E 5 202 HIS 202 138 138 HIS HIS R . n 
E 5 203 ARG 203 139 139 ARG ARG R . n 
E 5 204 ALA 204 140 140 ALA ALA R . n 
E 5 205 ILE 205 141 141 ILE ILE R . n 
E 5 206 CYS 206 142 142 CYS CYS R . n 
E 5 207 ARG 207 143 143 ARG ARG R . n 
E 5 208 PRO 208 144 144 PRO PRO R . n 
E 5 209 MET 209 145 ?   ?   ?   R . n 
E 5 210 LEU 210 146 ?   ?   ?   R . n 
E 5 211 ALA 211 147 ?   ?   ?   R . n 
E 5 212 TYR 212 148 ?   ?   ?   R . n 
E 5 213 ARG 213 149 ?   ?   ?   R . n 
E 5 214 HIS 214 150 ?   ?   ?   R . n 
E 5 215 GLY 215 151 ?   ?   ?   R . n 
E 5 216 SER 216 152 ?   ?   ?   R . n 
E 5 217 GLY 217 153 ?   ?   ?   R . n 
E 5 218 ALA 218 154 ?   ?   ?   R . n 
E 5 219 HIS 219 155 ?   ?   ?   R . n 
E 5 220 TRP 220 156 ?   ?   ?   R . n 
E 5 221 ASN 221 157 157 ASN ASN R . n 
E 5 222 ARG 222 158 158 ARG ARG R . n 
E 5 223 PRO 223 159 159 PRO PRO R . n 
E 5 224 VAL 224 160 160 VAL VAL R . n 
E 5 225 LEU 225 161 161 LEU LEU R . n 
E 5 226 VAL 226 162 162 VAL VAL R . n 
E 5 227 ALA 227 163 163 ALA ALA R . n 
E 5 228 TRP 228 164 164 TRP TRP R . n 
E 5 229 ALA 229 165 165 ALA ALA R . n 
E 5 230 PHE 230 166 166 PHE PHE R . n 
E 5 231 SER 231 167 167 SER SER R . n 
E 5 232 LEU 232 168 168 LEU LEU R . n 
E 5 233 LEU 233 169 169 LEU LEU R . n 
E 5 234 LEU 234 170 170 LEU LEU R . n 
E 5 235 SER 235 171 171 SER SER R . n 
E 5 236 LEU 236 172 172 LEU LEU R . n 
E 5 237 PRO 237 173 173 PRO PRO R . n 
E 5 238 GLN 238 174 174 GLN GLN R . n 
E 5 239 LEU 239 175 175 LEU LEU R . n 
E 5 240 PHE 240 176 176 PHE PHE R . n 
E 5 241 ILE 241 177 177 ILE ILE R . n 
E 5 242 PHE 242 178 178 PHE PHE R . n 
E 5 243 ALA 243 179 179 ALA ALA R . n 
E 5 244 GLN 244 180 180 GLN GLN R . n 
E 5 245 ARG 245 181 ?   ?   ?   R . n 
E 5 246 ASN 246 182 ?   ?   ?   R . n 
E 5 247 VAL 247 183 ?   ?   ?   R . n 
E 5 248 GLU 248 184 ?   ?   ?   R . n 
E 5 249 GLY 249 185 ?   ?   ?   R . n 
E 5 250 GLY 250 186 ?   ?   ?   R . n 
E 5 251 SER 251 187 ?   ?   ?   R . n 
E 5 252 GLY 252 188 ?   ?   ?   R . n 
E 5 253 VAL 253 189 ?   ?   ?   R . n 
E 5 254 THR 254 190 190 THR THR R . n 
E 5 255 ASP 255 191 191 ASP ASP R . n 
E 5 256 CYS 256 192 192 CYS CYS R . n 
E 5 257 TRP 257 193 193 TRP TRP R . n 
E 5 258 ALA 258 194 194 ALA ALA R . n 
E 5 259 CYS 259 195 195 CYS CYS R . n 
E 5 260 PHE 260 196 196 PHE PHE R . n 
E 5 261 ALA 261 197 ?   ?   ?   R . n 
E 5 262 GLU 262 198 ?   ?   ?   R . n 
E 5 263 PRO 263 199 ?   ?   ?   R . n 
E 5 264 TRP 264 200 200 TRP TRP R . n 
E 5 265 GLY 265 201 201 GLY GLY R . n 
E 5 266 ARG 266 202 202 ARG ARG R . n 
E 5 267 ARG 267 203 203 ARG ARG R . n 
E 5 268 THR 268 204 204 THR THR R . n 
E 5 269 TYR 269 205 205 TYR TYR R . n 
E 5 270 VAL 270 206 206 VAL VAL R . n 
E 5 271 THR 271 207 207 THR THR R . n 
E 5 272 TRP 272 208 208 TRP TRP R . n 
E 5 273 ILE 273 209 209 ILE ILE R . n 
E 5 274 ALA 274 210 210 ALA ALA R . n 
E 5 275 LEU 275 211 211 LEU LEU R . n 
E 5 276 MET 276 212 212 MET MET R . n 
E 5 277 VAL 277 213 213 VAL VAL R . n 
E 5 278 PHE 278 214 214 PHE PHE R . n 
E 5 279 VAL 279 215 215 VAL VAL R . n 
E 5 280 ALA 280 216 216 ALA ALA R . n 
E 5 281 PRO 281 217 217 PRO PRO R . n 
E 5 282 THR 282 218 218 THR THR R . n 
E 5 283 LEU 283 219 219 LEU LEU R . n 
E 5 284 GLY 284 220 220 GLY GLY R . n 
E 5 285 ILE 285 221 221 ILE ILE R . n 
E 5 286 ALA 286 222 222 ALA ALA R . n 
E 5 287 ALA 287 223 223 ALA ALA R . n 
E 5 288 CYS 288 224 224 CYS CYS R . n 
E 5 289 GLN 289 225 225 GLN GLN R . n 
E 5 290 VAL 290 226 226 VAL VAL R . n 
E 5 291 LEU 291 227 227 LEU LEU R . n 
E 5 292 ILE 292 228 228 ILE ILE R . n 
E 5 293 PHE 293 229 229 PHE PHE R . n 
E 5 294 ARG 294 230 230 ARG ARG R . n 
E 5 295 GLU 295 231 231 GLU GLU R . n 
E 5 296 ILE 296 232 232 ILE ILE R . n 
E 5 297 HIS 297 233 233 HIS HIS R . n 
E 5 298 ALA 298 234 234 ALA ALA R . n 
E 5 299 SER 299 235 ?   ?   ?   R . n 
E 5 300 LEU 300 236 ?   ?   ?   R . n 
E 5 301 VAL 301 237 ?   ?   ?   R . n 
E 5 302 PRO 302 238 ?   ?   ?   R . n 
E 5 303 GLY 303 239 ?   ?   ?   R . n 
E 5 304 PRO 304 240 ?   ?   ?   R . n 
E 5 305 SER 305 241 ?   ?   ?   R . n 
E 5 306 GLU 306 242 ?   ?   ?   R . n 
E 5 307 ARG 307 243 ?   ?   ?   R . n 
E 5 308 PRO 308 244 ?   ?   ?   R . n 
E 5 309 GLY 309 245 ?   ?   ?   R . n 
E 5 310 GLY 310 246 ?   ?   ?   R . n 
E 5 311 ARG 311 247 ?   ?   ?   R . n 
E 5 312 ARG 312 248 ?   ?   ?   R . n 
E 5 313 ARG 313 249 ?   ?   ?   R . n 
E 5 314 GLY 314 250 ?   ?   ?   R . n 
E 5 315 ARG 315 251 ?   ?   ?   R . n 
E 5 316 ARG 316 252 ?   ?   ?   R . n 
E 5 317 THR 317 253 ?   ?   ?   R . n 
E 5 318 GLY 318 254 ?   ?   ?   R . n 
E 5 319 SER 319 255 ?   ?   ?   R . n 
E 5 320 PRO 320 256 ?   ?   ?   R . n 
E 5 321 GLY 321 257 ?   ?   ?   R . n 
E 5 322 GLU 322 258 ?   ?   ?   R . n 
E 5 323 GLY 323 259 ?   ?   ?   R . n 
E 5 324 ALA 324 260 ?   ?   ?   R . n 
E 5 325 HIS 325 261 ?   ?   ?   R . n 
E 5 326 VAL 326 262 ?   ?   ?   R . n 
E 5 327 SER 327 263 ?   ?   ?   R . n 
E 5 328 ALA 328 264 264 ALA ALA R . n 
E 5 329 ALA 329 265 265 ALA ALA R . n 
E 5 330 VAL 330 266 266 VAL VAL R . n 
E 5 331 ALA 331 267 267 ALA ALA R . n 
E 5 332 LYS 332 268 268 LYS LYS R . n 
E 5 333 THR 333 269 269 THR THR R . n 
E 5 334 VAL 334 270 270 VAL VAL R . n 
E 5 335 ARG 335 271 271 ARG ARG R . n 
E 5 336 MET 336 272 272 MET MET R . n 
E 5 337 THR 337 273 273 THR THR R . n 
E 5 338 LEU 338 274 274 LEU LEU R . n 
E 5 339 VAL 339 275 275 VAL VAL R . n 
E 5 340 ILE 340 276 276 ILE ILE R . n 
E 5 341 VAL 341 277 277 VAL VAL R . n 
E 5 342 VAL 342 278 278 VAL VAL R . n 
E 5 343 VAL 343 279 279 VAL VAL R . n 
E 5 344 TYR 344 280 280 TYR TYR R . n 
E 5 345 VAL 345 281 281 VAL VAL R . n 
E 5 346 LEU 346 282 282 LEU LEU R . n 
E 5 347 CYS 347 283 283 CYS CYS R . n 
E 5 348 TRP 348 284 284 TRP TRP R . n 
E 5 349 ALA 349 285 285 ALA ALA R . n 
E 5 350 PRO 350 286 286 PRO PRO R . n 
E 5 351 PHE 351 287 287 PHE PHE R . n 
E 5 352 PHE 352 288 288 PHE PHE R . n 
E 5 353 LEU 353 289 289 LEU LEU R . n 
E 5 354 VAL 354 290 290 VAL VAL R . n 
E 5 355 GLN 355 291 291 GLN GLN R . n 
E 5 356 LEU 356 292 292 LEU LEU R . n 
E 5 357 TRP 357 293 293 TRP TRP R . n 
E 5 358 ALA 358 294 294 ALA ALA R . n 
E 5 359 ALA 359 295 295 ALA ALA R . n 
E 5 360 TRP 360 296 296 TRP TRP R . n 
E 5 361 ASP 361 297 297 ASP ASP R . n 
E 5 362 PRO 362 298 298 PRO PRO R . n 
E 5 363 GLU 363 299 ?   ?   ?   R . n 
E 5 364 ALA 364 300 ?   ?   ?   R . n 
E 5 365 PRO 365 301 ?   ?   ?   R . n 
E 5 366 LEU 366 302 ?   ?   ?   R . n 
E 5 367 GLU 367 303 ?   ?   ?   R . n 
E 5 368 GLY 368 304 ?   ?   ?   R . n 
E 5 369 ALA 369 305 ?   ?   ?   R . n 
E 5 370 PRO 370 306 306 PRO PRO R . n 
E 5 371 PHE 371 307 307 PHE PHE R . n 
E 5 372 VAL 372 308 308 VAL VAL R . n 
E 5 373 LEU 373 309 309 LEU LEU R . n 
E 5 374 LEU 374 310 310 LEU LEU R . n 
E 5 375 MET 375 311 311 MET MET R . n 
E 5 376 LEU 376 312 312 LEU LEU R . n 
E 5 377 LEU 377 313 313 LEU LEU R . n 
E 5 378 ALA 378 314 314 ALA ALA R . n 
E 5 379 SER 379 315 315 SER SER R . n 
E 5 380 LEU 380 316 316 LEU LEU R . n 
E 5 381 ASN 381 317 317 ASN ASN R . n 
E 5 382 SER 382 318 318 SER SER R . n 
E 5 383 CYS 383 319 319 CYS CYS R . n 
E 5 384 THR 384 320 320 THR THR R . n 
E 5 385 ASN 385 321 321 ASN ASN R . n 
E 5 386 PRO 386 322 322 PRO PRO R . n 
E 5 387 TRP 387 323 323 TRP TRP R . n 
E 5 388 ILE 388 324 324 ILE ILE R . n 
E 5 389 TYR 389 325 325 TYR TYR R . n 
E 5 390 ALA 390 326 326 ALA ALA R . n 
E 5 391 SER 391 327 327 SER SER R . n 
E 5 392 PHE 392 328 328 PHE PHE R . n 
E 5 393 SER 393 329 329 SER SER R . n 
E 5 394 SER 394 330 330 SER SER R . n 
E 5 395 SER 395 331 331 SER SER R . n 
E 5 396 VAL 396 332 332 VAL VAL R . n 
E 5 397 SER 397 333 333 SER SER R . n 
E 5 398 SER 398 334 334 SER SER R . n 
E 5 399 GLU 399 335 335 GLU GLU R . n 
E 5 400 LEU 400 336 336 LEU LEU R . n 
E 5 401 ARG 401 337 337 ARG ARG R . n 
E 5 402 SER 402 466 ?   ?   ?   R . n 
E 5 403 LEU 403 467 ?   ?   ?   R . n 
E 5 404 LEU 404 468 ?   ?   ?   R . n 
E 5 405 CYS 405 469 ?   ?   ?   R . n 
E 5 406 CYS 406 470 ?   ?   ?   R . n 
E 5 407 ALA 407 471 ?   ?   ?   R . n 
E 5 408 ARG 408 472 ?   ?   ?   R . n 
E 5 409 GLY 409 473 ?   ?   ?   R . n 
E 5 410 ARG 410 474 ?   ?   ?   R . n 
E 5 411 THR 411 475 ?   ?   ?   R . n 
E 5 412 PRO 412 476 ?   ?   ?   R . n 
E 5 413 PRO 413 477 ?   ?   ?   R . n 
E 5 414 SER 414 478 ?   ?   ?   R . n 
E 5 415 LEU 415 479 ?   ?   ?   R . n 
E 5 416 GLY 416 480 ?   ?   ?   R . n 
E 5 417 PRO 417 481 ?   ?   ?   R . n 
E 5 418 GLN 418 482 ?   ?   ?   R . n 
E 5 419 ASP 419 483 ?   ?   ?   R . n 
E 5 420 GLU 420 484 ?   ?   ?   R . n 
E 5 421 SER 421 485 ?   ?   ?   R . n 
E 5 422 CYS 422 486 ?   ?   ?   R . n 
E 5 423 THR 423 487 ?   ?   ?   R . n 
E 5 424 THR 424 488 ?   ?   ?   R . n 
E 5 425 ALA 425 489 ?   ?   ?   R . n 
E 5 426 SER 426 490 ?   ?   ?   R . n 
E 5 427 SER 427 491 ?   ?   ?   R . n 
E 5 428 SER 428 492 ?   ?   ?   R . n 
E 5 429 LEU 429 493 ?   ?   ?   R . n 
E 5 430 ALA 430 494 ?   ?   ?   R . n 
E 5 431 LYS 431 495 ?   ?   ?   R . n 
E 5 432 ASP 432 496 ?   ?   ?   R . n 
E 5 433 THR 433 497 ?   ?   ?   R . n 
E 5 434 SER 434 498 ?   ?   ?   R . n 
E 5 435 SER 435 499 ?   ?   ?   R . n 
E 5 436 ALA 436 500 500 ALA ALA R . n 
E 5 437 ARG 437 501 501 ARG ARG R . n 
E 5 438 ARG 438 502 502 ARG ARG R . n 
E 5 439 GLN 439 503 503 GLN GLN R . n 
E 5 440 LEU 440 504 504 LEU LEU R . n 
E 5 441 ALA 441 505 505 ALA ALA R . n 
E 5 442 ASP 442 506 506 ASP ASP R . n 
E 5 443 LEU 443 507 507 LEU LEU R . n 
E 5 444 GLU 444 508 508 GLU GLU R . n 
E 5 445 ASP 445 509 509 ASP ASP R . n 
E 5 446 ASN 446 510 510 ASN ASN R . n 
E 5 447 TRP 447 511 511 TRP TRP R . n 
E 5 448 GLU 448 512 512 GLU GLU R . n 
E 5 449 THR 449 513 513 THR THR R . n 
E 5 450 LEU 450 514 514 LEU LEU R . n 
E 5 451 ASN 451 515 515 ASN ASN R . n 
E 5 452 ASP 452 516 516 ASP ASP R . n 
E 5 453 ASN 453 517 517 ASN ASN R . n 
E 5 454 LEU 454 518 518 LEU LEU R . n 
E 5 455 LYS 455 519 519 LYS LYS R . n 
E 5 456 VAL 456 520 520 VAL VAL R . n 
E 5 457 ILE 457 521 521 ILE ILE R . n 
E 5 458 GLU 458 522 522 GLU GLU R . n 
E 5 459 LYS 459 523 523 LYS LYS R . n 
E 5 460 ALA 460 524 524 ALA ALA R . n 
E 5 461 ASP 461 525 525 ASP ASP R . n 
E 5 462 ASN 462 526 526 ASN ASN R . n 
E 5 463 ALA 463 527 527 ALA ALA R . n 
E 5 464 ALA 464 528 528 ALA ALA R . n 
E 5 465 GLN 465 529 529 GLN GLN R . n 
E 5 466 VAL 466 530 530 VAL VAL R . n 
E 5 467 LYS 467 531 531 LYS LYS R . n 
E 5 468 ASP 468 532 532 ASP ASP R . n 
E 5 469 ALA 469 533 533 ALA ALA R . n 
E 5 470 LEU 470 534 534 LEU LEU R . n 
E 5 471 THR 471 535 535 THR THR R . n 
E 5 472 LYS 472 536 536 LYS LYS R . n 
E 5 473 MET 473 537 537 MET MET R . n 
E 5 474 ARG 474 538 538 ARG ARG R . n 
E 5 475 ALA 475 539 539 ALA ALA R . n 
E 5 476 ALA 476 540 540 ALA ALA R . n 
E 5 477 ALA 477 541 541 ALA ALA R . n 
E 5 478 LEU 478 542 542 LEU LEU R . n 
E 5 479 ASP 479 543 543 ASP ASP R . n 
E 5 480 ALA 480 544 544 ALA ALA R . n 
E 5 481 GLN 481 545 545 GLN GLN R . n 
E 5 482 LYS 482 546 546 LYS LYS R . n 
E 5 483 ALA 483 547 547 ALA ALA R . n 
E 5 484 THR 484 548 548 THR THR R . n 
E 5 485 PRO 485 549 549 PRO PRO R . n 
E 5 486 PRO 486 550 ?   ?   ?   R . n 
E 5 487 LYS 487 551 ?   ?   ?   R . n 
E 5 488 LEU 488 552 ?   ?   ?   R . n 
E 5 489 GLU 489 553 ?   ?   ?   R . n 
E 5 490 ASP 490 554 ?   ?   ?   R . n 
E 5 491 LYS 491 555 ?   ?   ?   R . n 
E 5 492 SER 492 556 ?   ?   ?   R . n 
E 5 493 PRO 493 557 ?   ?   ?   R . n 
E 5 494 ASP 494 558 ?   ?   ?   R . n 
E 5 495 SER 495 559 ?   ?   ?   R . n 
E 5 496 PRO 496 560 ?   ?   ?   R . n 
E 5 497 GLU 497 561 ?   ?   ?   R . n 
E 5 498 MET 498 562 562 MET MET R . n 
E 5 499 LYS 499 563 563 LYS LYS R . n 
E 5 500 ASP 500 564 564 ASP ASP R . n 
E 5 501 PHE 501 565 565 PHE PHE R . n 
E 5 502 ARG 502 566 566 ARG ARG R . n 
E 5 503 HIS 503 567 567 HIS HIS R . n 
E 5 504 GLY 504 568 568 GLY GLY R . n 
E 5 505 PHE 505 569 569 PHE PHE R . n 
E 5 506 ASP 506 570 570 ASP ASP R . n 
E 5 507 ILE 507 571 571 ILE ILE R . n 
E 5 508 LEU 508 572 572 LEU LEU R . n 
E 5 509 VAL 509 573 573 VAL VAL R . n 
E 5 510 GLY 510 574 574 GLY GLY R . n 
E 5 511 GLN 511 575 575 GLN GLN R . n 
E 5 512 ILE 512 576 576 ILE ILE R . n 
E 5 513 ASP 513 577 577 ASP ASP R . n 
E 5 514 ASP 514 578 578 ASP ASP R . n 
E 5 515 ALA 515 579 579 ALA ALA R . n 
E 5 516 LEU 516 580 580 LEU LEU R . n 
E 5 517 LYS 517 581 581 LYS LYS R . n 
E 5 518 LEU 518 582 582 LEU LEU R . n 
E 5 519 ALA 519 583 583 ALA ALA R . n 
E 5 520 ASN 520 584 584 ASN ASN R . n 
E 5 521 GLU 521 585 585 GLU GLU R . n 
E 5 522 GLY 522 586 586 GLY GLY R . n 
E 5 523 LYS 523 587 587 LYS LYS R . n 
E 5 524 VAL 524 588 588 VAL VAL R . n 
E 5 525 LYS 525 589 589 LYS LYS R . n 
E 5 526 GLU 526 590 590 GLU GLU R . n 
E 5 527 ALA 527 591 591 ALA ALA R . n 
E 5 528 GLN 528 592 592 GLN GLN R . n 
E 5 529 ALA 529 593 593 ALA ALA R . n 
E 5 530 ALA 530 594 594 ALA ALA R . n 
E 5 531 ALA 531 595 595 ALA ALA R . n 
E 5 532 GLU 532 596 596 GLU GLU R . n 
E 5 533 GLN 533 597 597 GLN GLN R . n 
E 5 534 LEU 534 598 598 LEU LEU R . n 
E 5 535 LYS 535 599 599 LYS LYS R . n 
E 5 536 THR 536 600 600 THR THR R . n 
E 5 537 THR 537 601 601 THR THR R . n 
E 5 538 ARG 538 602 602 ARG ARG R . n 
E 5 539 ASN 539 603 603 ASN ASN R . n 
E 5 540 ALA 540 604 604 ALA ALA R . n 
E 5 541 TYR 541 605 605 TYR TYR R . n 
E 5 542 ILE 542 606 606 ILE ILE R . n 
E 5 543 GLN 543 607 607 GLN GLN R . n 
E 5 544 LYS 544 608 608 LYS LYS R . n 
E 5 545 TYR 545 609 609 TYR TYR R . n 
E 5 546 LEU 546 610 610 LEU LEU R . n 
E 5 547 ARG 547 611 611 ARG ARG R . n 
E 5 548 ALA 548 612 612 ALA ALA R . n 
E 5 549 ARG 549 613 613 ARG ARG R . n 
E 5 550 SER 550 614 614 SER SER R . n 
E 5 551 THR 551 615 615 THR THR R . n 
E 5 552 LEU 552 616 616 LEU LEU R . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A TYR 22  ? CG  ? A TYR 22  CG  
2   1 Y 1 A TYR 22  ? CD1 ? A TYR 22  CD1 
3   1 Y 1 A TYR 22  ? CD2 ? A TYR 22  CD2 
4   1 Y 1 A TYR 22  ? CE1 ? A TYR 22  CE1 
5   1 Y 1 A TYR 22  ? CE2 ? A TYR 22  CE2 
6   1 Y 1 A TYR 22  ? CZ  ? A TYR 22  CZ  
7   1 Y 1 A TYR 22  ? OH  ? A TYR 22  OH  
8   1 Y 1 A CYS 30  ? SG  ? A CYS 30  SG  
9   1 Y 1 A SER 32  ? OG  ? A SER 32  OG  
10  1 Y 1 A ASN 43  ? CG  ? A ASN 43  CG  
11  1 Y 1 A ASN 43  ? OD1 ? A ASN 43  OD1 
12  1 Y 1 A ASN 43  ? ND2 ? A ASN 43  ND2 
13  1 Y 1 A GLU 49  ? CG  ? A GLU 49  CG  
14  1 Y 1 A GLU 49  ? CD  ? A GLU 49  CD  
15  1 Y 1 A GLU 49  ? OE1 ? A GLU 49  OE1 
16  1 Y 1 A GLU 49  ? OE2 ? A GLU 49  OE2 
17  1 Y 1 A LYS 50  ? CG  ? A LYS 50  CG  
18  1 Y 1 A LYS 50  ? CD  ? A LYS 50  CD  
19  1 Y 1 A LYS 50  ? CE  ? A LYS 50  CE  
20  1 Y 1 A LYS 50  ? NZ  ? A LYS 50  NZ  
21  1 Y 1 A CYS 51  ? SG  ? A CYS 51  SG  
22  1 Y 1 A ARG 52  ? CG  ? A ARG 52  CG  
23  1 Y 1 A ARG 52  ? CD  ? A ARG 52  CD  
24  1 Y 1 A ARG 52  ? NE  ? A ARG 52  NE  
25  1 Y 1 A ARG 52  ? CZ  ? A ARG 52  CZ  
26  1 Y 1 A ARG 52  ? NH1 ? A ARG 52  NH1 
27  1 Y 1 A ARG 52  ? NH2 ? A ARG 52  NH2 
28  1 Y 1 A ARG 53  ? CG  ? A ARG 53  CG  
29  1 Y 1 A ARG 53  ? CD  ? A ARG 53  CD  
30  1 Y 1 A ARG 53  ? NE  ? A ARG 53  NE  
31  1 Y 1 A ARG 53  ? CZ  ? A ARG 53  CZ  
32  1 Y 1 A ARG 53  ? NH1 ? A ARG 53  NH1 
33  1 Y 1 A ARG 53  ? NH2 ? A ARG 53  NH2 
34  1 Y 1 A THR 54  ? OG1 ? A THR 54  OG1 
35  1 Y 1 A THR 54  ? CG2 ? A THR 54  CG2 
36  1 Y 1 A CYS 55  ? SG  ? A CYS 55  SG  
37  1 Y 1 A VAL 56  ? CG1 ? A VAL 56  CG1 
38  1 Y 1 A VAL 56  ? CG2 ? A VAL 56  CG2 
39  1 Y 1 R ARG 38  ? CG  ? E ARG 102 CG  
40  1 Y 1 R ARG 38  ? CD  ? E ARG 102 CD  
41  1 Y 1 R ARG 38  ? NE  ? E ARG 102 NE  
42  1 Y 1 R ARG 38  ? CZ  ? E ARG 102 CZ  
43  1 Y 1 R ARG 38  ? NH1 ? E ARG 102 NH1 
44  1 Y 1 R ARG 38  ? NH2 ? E ARG 102 NH2 
45  1 Y 1 R ARG 64  ? CG  ? E ARG 128 CG  
46  1 Y 1 R ARG 64  ? CD  ? E ARG 128 CD  
47  1 Y 1 R ARG 64  ? NE  ? E ARG 128 NE  
48  1 Y 1 R ARG 64  ? CZ  ? E ARG 128 CZ  
49  1 Y 1 R ARG 64  ? NH1 ? E ARG 128 NH1 
50  1 Y 1 R ARG 64  ? NH2 ? E ARG 128 NH2 
51  1 Y 1 R ARG 65  ? CG  ? E ARG 129 CG  
52  1 Y 1 R ARG 65  ? CD  ? E ARG 129 CD  
53  1 Y 1 R ARG 65  ? NE  ? E ARG 129 NE  
54  1 Y 1 R ARG 65  ? CZ  ? E ARG 129 CZ  
55  1 Y 1 R ARG 65  ? NH1 ? E ARG 129 NH1 
56  1 Y 1 R ARG 65  ? NH2 ? E ARG 129 NH2 
57  1 Y 1 R ARG 67  ? CG  ? E ARG 131 CG  
58  1 Y 1 R ARG 67  ? CD  ? E ARG 131 CD  
59  1 Y 1 R ARG 67  ? NE  ? E ARG 131 NE  
60  1 Y 1 R ARG 67  ? CZ  ? E ARG 131 CZ  
61  1 Y 1 R ARG 67  ? NH1 ? E ARG 131 NH1 
62  1 Y 1 R ARG 67  ? NH2 ? E ARG 131 NH2 
63  1 Y 1 R ARG 68  ? CG  ? E ARG 132 CG  
64  1 Y 1 R ARG 68  ? CD  ? E ARG 132 CD  
65  1 Y 1 R ARG 68  ? NE  ? E ARG 132 NE  
66  1 Y 1 R ARG 68  ? CZ  ? E ARG 132 CZ  
67  1 Y 1 R ARG 68  ? NH1 ? E ARG 132 NH1 
68  1 Y 1 R ARG 68  ? NH2 ? E ARG 132 NH2 
69  1 Y 1 R HIS 70  ? CG  ? E HIS 134 CG  
70  1 Y 1 R HIS 70  ? ND1 ? E HIS 134 ND1 
71  1 Y 1 R HIS 70  ? CD2 ? E HIS 134 CD2 
72  1 Y 1 R HIS 70  ? CE1 ? E HIS 134 CE1 
73  1 Y 1 R HIS 70  ? NE2 ? E HIS 134 NE2 
74  1 Y 1 R PHE 77  ? CG  ? E PHE 141 CG  
75  1 Y 1 R PHE 77  ? CD1 ? E PHE 141 CD1 
76  1 Y 1 R PHE 77  ? CD2 ? E PHE 141 CD2 
77  1 Y 1 R PHE 77  ? CE1 ? E PHE 141 CE1 
78  1 Y 1 R PHE 77  ? CE2 ? E PHE 141 CE2 
79  1 Y 1 R PHE 77  ? CZ  ? E PHE 141 CZ  
80  1 Y 1 R LEU 90  ? CG  ? E LEU 154 CG  
81  1 Y 1 R LEU 90  ? CD1 ? E LEU 154 CD1 
82  1 Y 1 R LEU 90  ? CD2 ? E LEU 154 CD2 
83  1 Y 1 R VAL 93  ? CG1 ? E VAL 157 CG1 
84  1 Y 1 R VAL 93  ? CG2 ? E VAL 157 CG2 
85  1 Y 1 R LYS 100 ? CG  ? E LYS 164 CG  
86  1 Y 1 R LYS 100 ? CD  ? E LYS 164 CD  
87  1 Y 1 R LYS 100 ? CE  ? E LYS 164 CE  
88  1 Y 1 R LYS 100 ? NZ  ? E LYS 164 NZ  
89  1 Y 1 R PHE 105 ? CG  ? E PHE 169 CG  
90  1 Y 1 R PHE 105 ? CD1 ? E PHE 169 CD1 
91  1 Y 1 R PHE 105 ? CD2 ? E PHE 169 CD2 
92  1 Y 1 R PHE 105 ? CE1 ? E PHE 169 CE1 
93  1 Y 1 R PHE 105 ? CE2 ? E PHE 169 CE2 
94  1 Y 1 R PHE 105 ? CZ  ? E PHE 169 CZ  
95  1 Y 1 R ARG 106 ? CG  ? E ARG 170 CG  
96  1 Y 1 R ARG 106 ? CD  ? E ARG 170 CD  
97  1 Y 1 R ARG 106 ? NE  ? E ARG 170 NE  
98  1 Y 1 R ARG 106 ? CZ  ? E ARG 170 CZ  
99  1 Y 1 R ARG 106 ? NH1 ? E ARG 170 NH1 
100 1 Y 1 R ARG 106 ? NH2 ? E ARG 170 NH2 
101 1 Y 1 R ASP 109 ? CG  ? E ASP 173 CG  
102 1 Y 1 R ASP 109 ? OD1 ? E ASP 173 OD1 
103 1 Y 1 R ASP 109 ? OD2 ? E ASP 173 OD2 
104 1 Y 1 R LEU 111 ? CG  ? E LEU 175 CG  
105 1 Y 1 R LEU 111 ? CD1 ? E LEU 175 CD1 
106 1 Y 1 R LEU 111 ? CD2 ? E LEU 175 CD2 
107 1 Y 1 R ARG 113 ? CG  ? E ARG 177 CG  
108 1 Y 1 R ARG 113 ? CD  ? E ARG 177 CD  
109 1 Y 1 R ARG 113 ? NE  ? E ARG 177 NE  
110 1 Y 1 R ARG 113 ? CZ  ? E ARG 177 CZ  
111 1 Y 1 R ARG 113 ? NH1 ? E ARG 177 NH1 
112 1 Y 1 R ARG 113 ? NH2 ? E ARG 177 NH2 
113 1 Y 1 R VAL 115 ? CG1 ? E VAL 179 CG1 
114 1 Y 1 R VAL 115 ? CG2 ? E VAL 179 CG2 
115 1 Y 1 R MET 129 ? CG  ? E MET 193 CG  
116 1 Y 1 R MET 129 ? SD  ? E MET 193 SD  
117 1 Y 1 R MET 129 ? CE  ? E MET 193 CE  
118 1 Y 1 R MET 133 ? CG  ? E MET 197 CG  
119 1 Y 1 R MET 133 ? SD  ? E MET 197 SD  
120 1 Y 1 R MET 133 ? CE  ? E MET 197 CE  
121 1 Y 1 R LEU 135 ? CG  ? E LEU 199 CG  
122 1 Y 1 R LEU 135 ? CD1 ? E LEU 199 CD1 
123 1 Y 1 R LEU 135 ? CD2 ? E LEU 199 CD2 
124 1 Y 1 R ILE 141 ? CG1 ? E ILE 205 CG1 
125 1 Y 1 R ILE 141 ? CG2 ? E ILE 205 CG2 
126 1 Y 1 R ILE 141 ? CD1 ? E ILE 205 CD1 
127 1 Y 1 R ARG 143 ? CG  ? E ARG 207 CG  
128 1 Y 1 R ARG 143 ? CD  ? E ARG 207 CD  
129 1 Y 1 R ARG 143 ? NE  ? E ARG 207 NE  
130 1 Y 1 R ARG 143 ? CZ  ? E ARG 207 CZ  
131 1 Y 1 R ARG 143 ? NH1 ? E ARG 207 NH1 
132 1 Y 1 R ARG 143 ? NH2 ? E ARG 207 NH2 
133 1 Y 1 R ARG 158 ? CG  ? E ARG 222 CG  
134 1 Y 1 R ARG 158 ? CD  ? E ARG 222 CD  
135 1 Y 1 R ARG 158 ? NE  ? E ARG 222 NE  
136 1 Y 1 R ARG 158 ? CZ  ? E ARG 222 CZ  
137 1 Y 1 R ARG 158 ? NH1 ? E ARG 222 NH1 
138 1 Y 1 R ARG 158 ? NH2 ? E ARG 222 NH2 
139 1 Y 1 R LEU 168 ? CG  ? E LEU 232 CG  
140 1 Y 1 R LEU 168 ? CD1 ? E LEU 232 CD1 
141 1 Y 1 R LEU 168 ? CD2 ? E LEU 232 CD2 
142 1 Y 1 R LEU 169 ? CG  ? E LEU 233 CG  
143 1 Y 1 R LEU 169 ? CD1 ? E LEU 233 CD1 
144 1 Y 1 R LEU 169 ? CD2 ? E LEU 233 CD2 
145 1 Y 1 R LEU 172 ? CG  ? E LEU 236 CG  
146 1 Y 1 R LEU 172 ? CD1 ? E LEU 236 CD1 
147 1 Y 1 R LEU 172 ? CD2 ? E LEU 236 CD2 
148 1 Y 1 R LEU 175 ? CG  ? E LEU 239 CG  
149 1 Y 1 R LEU 175 ? CD1 ? E LEU 239 CD1 
150 1 Y 1 R LEU 175 ? CD2 ? E LEU 239 CD2 
151 1 Y 1 R PHE 176 ? CG  ? E PHE 240 CG  
152 1 Y 1 R PHE 176 ? CD1 ? E PHE 240 CD1 
153 1 Y 1 R PHE 176 ? CD2 ? E PHE 240 CD2 
154 1 Y 1 R PHE 176 ? CE1 ? E PHE 240 CE1 
155 1 Y 1 R PHE 176 ? CE2 ? E PHE 240 CE2 
156 1 Y 1 R PHE 176 ? CZ  ? E PHE 240 CZ  
157 1 Y 1 R GLN 180 ? CG  ? E GLN 244 CG  
158 1 Y 1 R GLN 180 ? CD  ? E GLN 244 CD  
159 1 Y 1 R GLN 180 ? OE1 ? E GLN 244 OE1 
160 1 Y 1 R GLN 180 ? NE2 ? E GLN 244 NE2 
161 1 Y 1 R CYS 195 ? SG  ? E CYS 259 SG  
162 1 Y 1 R PHE 196 ? CG  ? E PHE 260 CG  
163 1 Y 1 R PHE 196 ? CD1 ? E PHE 260 CD1 
164 1 Y 1 R PHE 196 ? CD2 ? E PHE 260 CD2 
165 1 Y 1 R PHE 196 ? CE1 ? E PHE 260 CE1 
166 1 Y 1 R PHE 196 ? CE2 ? E PHE 260 CE2 
167 1 Y 1 R PHE 196 ? CZ  ? E PHE 260 CZ  
168 1 Y 1 R ARG 203 ? CG  ? E ARG 267 CG  
169 1 Y 1 R ARG 203 ? CD  ? E ARG 267 CD  
170 1 Y 1 R ARG 203 ? NE  ? E ARG 267 NE  
171 1 Y 1 R ARG 203 ? CZ  ? E ARG 267 CZ  
172 1 Y 1 R ARG 203 ? NH1 ? E ARG 267 NH1 
173 1 Y 1 R ARG 203 ? NH2 ? E ARG 267 NH2 
174 1 Y 1 R HIS 233 ? CG  ? E HIS 297 CG  
175 1 Y 1 R HIS 233 ? ND1 ? E HIS 297 ND1 
176 1 Y 1 R HIS 233 ? CD2 ? E HIS 297 CD2 
177 1 Y 1 R HIS 233 ? CE1 ? E HIS 297 CE1 
178 1 Y 1 R HIS 233 ? NE2 ? E HIS 297 NE2 
179 1 Y 1 R LYS 268 ? CG  ? E LYS 332 CG  
180 1 Y 1 R LYS 268 ? CD  ? E LYS 332 CD  
181 1 Y 1 R LYS 268 ? CE  ? E LYS 332 CE  
182 1 Y 1 R LYS 268 ? NZ  ? E LYS 332 NZ  
183 1 Y 1 R CYS 283 ? SG  ? E CYS 347 SG  
184 1 Y 1 R LEU 310 ? CG  ? E LEU 374 CG  
185 1 Y 1 R LEU 310 ? CD1 ? E LEU 374 CD1 
186 1 Y 1 R LEU 310 ? CD2 ? E LEU 374 CD2 
187 1 Y 1 R LEU 312 ? CG  ? E LEU 376 CG  
188 1 Y 1 R LEU 312 ? CD1 ? E LEU 376 CD1 
189 1 Y 1 R LEU 312 ? CD2 ? E LEU 376 CD2 
190 1 Y 1 R ASN 321 ? CG  ? E ASN 385 CG  
191 1 Y 1 R ASN 321 ? OD1 ? E ASN 385 OD1 
192 1 Y 1 R ASN 321 ? ND2 ? E ASN 385 ND2 
193 1 Y 1 R GLU 335 ? CG  ? E GLU 399 CG  
194 1 Y 1 R GLU 335 ? CD  ? E GLU 399 CD  
195 1 Y 1 R GLU 335 ? OE1 ? E GLU 399 OE1 
196 1 Y 1 R GLU 335 ? OE2 ? E GLU 399 OE2 
197 1 Y 1 R LEU 336 ? CG  ? E LEU 400 CG  
198 1 Y 1 R LEU 336 ? CD1 ? E LEU 400 CD1 
199 1 Y 1 R LEU 336 ? CD2 ? E LEU 400 CD2 
200 1 Y 1 R ARG 337 ? CG  ? E ARG 401 CG  
201 1 Y 1 R ARG 337 ? CD  ? E ARG 401 CD  
202 1 Y 1 R ARG 337 ? NE  ? E ARG 401 NE  
203 1 Y 1 R ARG 337 ? CZ  ? E ARG 401 CZ  
204 1 Y 1 R ARG 337 ? NH1 ? E ARG 401 NH1 
205 1 Y 1 R ARG 337 ? NH2 ? E ARG 401 NH2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9HB3 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9HB3 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9HB3 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9HB3 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.5 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'REAL-SPACE (WEIGHTED MAP SUM AT ATOM CENTERS)' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004  ? 7299 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.645  ? 9936 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 10.953 ? 2505 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.041  ? 1133 ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005  ? 1258 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9HB3 
_struct.title                        
'cryo-EM structure of inactive human arginine-vasopressin (AVP) V2 receptor (V2R) with Mambaquaretin1 K39A (MQK39A)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9HB3 
_struct_keywords.text            'GPCR, V2R, TVP, tolvaptan, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP MAMB1_DENAN A0A1Z0YU59 ? 1 RPSFCNLPVKPGPCNGFFSAFYYSQKTNKCHSFTYGGCKGNANRFSTIEKCRRTCVG 1   
2 PDB 9HB3        9HB3       ? 2 ? 1   
3 PDB 9HB3        9HB3       ? 3 ? 1   
4 PDB 9HB3        9HB3       ? 4 ? 1   
5 PDB 9HB3        9HB3       ? 5 ? 1   
6 UNP V2R_HUMAN   P30518     ? 5 
;ASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCL
ADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVA
WAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSER
PGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPW
IYASFSSSVSSELRSLLCC
;
4   
7 PDB 9HB3        9HB3       ? 5 ? 407 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9HB3 A 1   ? 57  ? A0A1Z0YU59 1   ? 57  ? 1   57  
2 2 9HB3 H 1   ? 231 ? 9HB3       1   ? 231 ? 1   231 
3 3 9HB3 K 1   ? 141 ? 9HB3       -5  ? 135 ? -5  135 
4 4 9HB3 L 1   ? 215 ? 9HB3       2   ? 216 ? 2   216 
5 5 9HB3 R 1   ? 67  ? 9HB3       -63 ? 3   ? -63 3   
6 6 9HB3 R 68  ? 406 ? P30518     4   ? 342 ? 4   470 
7 7 9HB3 R 407 ? 552 ? 9HB3       471 ? 616 ? 471 616 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9HB3 ALA A 39 ? UNP A0A1Z0YU59 LYS 39 variant  39 1 
6 9HB3 GLN R 86 ? UNP P30518     ASN 22 conflict 22 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 47  ? VAL A 56  ? THR A 47  VAL A 56  1 ? 10 
HELX_P HELX_P2  AA2 ARG B 90  ? THR B 94  ? ARG H 90  THR H 94  5 ? 5  
HELX_P HELX_P3  AA3 GLY B 107 ? LYS B 112 ? GLY H 107 LYS H 112 1 ? 6  
HELX_P HELX_P4  AA4 SER B 170 ? ALA B 172 ? SER H 170 ALA H 172 5 ? 3  
HELX_P HELX_P5  AA5 SER B 200 ? THR B 205 ? SER H 200 THR H 205 1 ? 6  
HELX_P HELX_P6  AA6 PRO B 216 ? ASN B 218 ? PRO H 216 ASN H 218 5 ? 3  
HELX_P HELX_P7  AA7 ASP C 80  ? LYS C 82  ? ASP K 74  LYS K 76  5 ? 3  
HELX_P HELX_P8  AA8 LYS C 93  ? THR C 97  ? LYS K 87  THR K 91  5 ? 5  
HELX_P HELX_P9  AA9 GLN D 79  ? PHE D 83  ? GLN L 80  PHE L 84  5 ? 5  
HELX_P HELX_P10 AB1 TYR D 93  ? VAL D 97  ? TYR L 94  VAL L 98  5 ? 5  
HELX_P HELX_P11 AB2 SER D 122 ? SER D 128 ? SER L 123 SER L 129 1 ? 7  
HELX_P HELX_P12 AB3 LYS D 184 ? HIS D 190 ? LYS L 185 HIS L 191 1 ? 7  
HELX_P HELX_P13 AB4 LEU E 100 ? GLY E 130 ? LEU R 36  GLY R 66  1 ? 31 
HELX_P HELX_P14 AB5 ARG E 131 ? GLY E 133 ? ARG R 67  GLY R 69  5 ? 3  
HELX_P HELX_P15 AB6 ALA E 136 ? ALA E 165 ? ALA R 72  ALA R 101 1 ? 30 
HELX_P HELX_P16 AB7 ALA E 174 ? ILE E 205 ? ALA R 110 ILE R 141 1 ? 32 
HELX_P HELX_P17 AB8 ARG E 222 ? LEU E 234 ? ARG R 158 LEU R 170 1 ? 13 
HELX_P HELX_P18 AB9 PRO E 237 ? PHE E 242 ? PRO R 173 PHE R 178 1 ? 6  
HELX_P HELX_P19 AC1 GLY E 265 ? PHE E 278 ? GLY R 201 PHE R 214 1 ? 14 
HELX_P HELX_P20 AC2 PHE E 278 ? ALA E 298 ? PHE R 214 ALA R 234 1 ? 21 
HELX_P HELX_P21 AC3 ALA E 329 ? ASP E 361 ? ALA R 265 ASP R 297 1 ? 33 
HELX_P HELX_P22 AC4 PHE E 371 ? LEU E 380 ? PHE R 307 LEU R 316 1 ? 10 
HELX_P HELX_P23 AC5 LEU E 380 ? SER E 393 ? LEU R 316 SER R 329 1 ? 14 
HELX_P HELX_P24 AC6 SER E 393 ? LEU E 400 ? SER R 329 LEU R 336 1 ? 8  
HELX_P HELX_P25 AC7 ARG E 437 ? ALA E 460 ? ARG R 501 ALA R 524 1 ? 24 
HELX_P HELX_P26 AC8 ASN E 462 ? ALA E 483 ? ASN R 526 ALA R 547 1 ? 22 
HELX_P HELX_P27 AC9 LYS E 499 ? GLU E 521 ? LYS R 563 GLU R 585 1 ? 23 
HELX_P HELX_P28 AD1 LYS E 523 ? ARG E 547 ? LYS R 587 ARG R 611 1 ? 25 
HELX_P HELX_P29 AD2 ALA E 548 ? THR E 551 ? ALA R 612 THR R 615 5 ? 4  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 14  SG ? ? ? 1_555 A CYS 38  SG ? ? A CYS 14  A CYS 38  1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf2 disulf ? ? B CYS 25  SG ? ? ? 1_555 B CYS 99  SG ? ? H CYS 25  H CYS 99  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf3 disulf ? ? B CYS 154 SG ? ? ? 1_555 B CYS 210 SG ? ? H CYS 154 H CYS 210 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf4 disulf ? ? C CYS 28  SG ? ? ? 1_555 C CYS 102 SG ? ? K CYS 22  K CYS 96  1_555 ? ? ? ? ? ? ? 2.035 ? ? 
disulf5 disulf ? ? D CYS 23  SG ? ? ? 1_555 D CYS 88  SG ? ? L CYS 24  L CYS 89  1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf6 disulf ? ? D CYS 135 SG ? ? ? 1_555 D CYS 195 SG ? ? L CYS 136 L CYS 196 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf7 disulf ? ? E CYS 176 SG ? ? ? 1_555 E CYS 256 SG ? ? R CYS 112 R CYS 192 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 14  ? CYS A 38  ? CYS A 14  ? 1_555 CYS A 38  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 25  ? CYS B 99  ? CYS H 25  ? 1_555 CYS H 99  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS B 154 ? CYS B 210 ? CYS H 154 ? 1_555 CYS H 210 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS C 28  ? CYS C 102 ? CYS K 22  ? 1_555 CYS K 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
5 CYS D 23  ? CYS D 88  ? CYS L 24  ? 1_555 CYS L 89  ? 1_555 SG SG . . . None 'Disulfide bridge' 
6 CYS D 135 ? CYS D 195 ? CYS L 136 ? 1_555 CYS L 196 ? 1_555 SG SG . . . None 'Disulfide bridge' 
7 CYS E 176 ? CYS E 256 ? CYS R 112 ? 1_555 CYS R 192 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 TRP 105 B . ? TRP 105 H PRO 106 B ? PRO 106 H 1 -4.42 
2 PHE 160 B . ? PHE 160 H PRO 161 B ? PRO 161 H 1 -3.57 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 4 ? 
AA3 ? 6 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 2 ? 
AA7 ? 3 ? 
AA8 ? 4 ? 
AA9 ? 6 ? 
AB1 ? 4 ? 
AB2 ? 6 ? 
AB3 ? 4 ? 
AB4 ? 4 ? 
AB5 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? anti-parallel 
AB2 5 6 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 18  ? TYR A 22  ? PHE A 18  TYR A 22  
AA1 2 HIS A 31  ? TYR A 35  ? HIS A 31  TYR A 35  
AA2 1 GLN B 6   ? SER B 10  ? GLN H 6   SER H 10  
AA2 2 GLY B 19  ? SER B 28  ? GLY H 19  SER H 28  
AA2 3 THR B 81  ? ASN B 87  ? THR H 81  ASN H 87  
AA2 4 PHE B 71  ? ASP B 76  ? PHE H 71  ASP H 76  
AA3 1 GLY B 13  ? VAL B 15  ? GLY H 13  VAL H 15  
AA3 2 GLY B 120 ? VAL B 125 ? GLY H 120 VAL H 125 
AA3 3 ALA B 95  ? TRP B 102 ? ALA H 95  TRP H 102 
AA3 4 SER B 36  ? GLN B 42  ? SER H 36  GLN H 42  
AA3 5 LEU B 48  ? ILE B 54  ? LEU H 48  ILE H 54  
AA3 6 THR B 61  ? TYR B 63  ? THR H 61  TYR H 63  
AA4 1 SER B 134 ? PHE B 136 ? SER H 134 PHE H 136 
AA4 2 LEU B 155 ? TYR B 159 ? LEU H 155 TYR H 159 
AA4 3 TYR B 190 ? VAL B 195 ? TYR H 190 VAL H 195 
AA4 4 HIS B 178 ? THR B 179 ? HIS H 178 THR H 179 
AA5 1 SER B 134 ? PHE B 136 ? SER H 134 PHE H 136 
AA5 2 LEU B 155 ? TYR B 159 ? LEU H 155 TYR H 159 
AA5 3 TYR B 190 ? VAL B 195 ? TYR H 190 VAL H 195 
AA5 4 VAL B 183 ? LEU B 184 ? VAL H 183 LEU H 184 
AA6 1 THR B 149 ? ALA B 151 ? THR H 149 ALA H 151 
AA6 2 THR B 197 ? PRO B 199 ? THR H 197 PRO H 199 
AA7 1 VAL B 164 ? TRP B 168 ? VAL H 164 TRP H 168 
AA7 2 TYR B 208 ? HIS B 214 ? TYR H 208 HIS H 214 
AA7 3 THR B 219 ? VAL B 225 ? THR H 219 VAL H 225 
AA8 1 GLN C 9   ? SER C 13  ? GLN K 3   SER K 7   
AA8 2 LEU C 24  ? SER C 31  ? LEU K 18  SER K 25  
AA8 3 THR C 84  ? MET C 89  ? THR K 78  MET K 83  
AA8 4 PHE C 74  ? ASP C 79  ? PHE K 68  ASP K 73  
AA9 1 LEU C 17  ? VAL C 18  ? LEU K 11  VAL K 12  
AA9 2 THR C 121 ? VAL C 125 ? THR K 115 VAL K 119 
AA9 3 ALA C 98  ? ASP C 105 ? ALA K 92  ASP K 99  
AA9 4 ALA C 39  ? GLN C 45  ? ALA K 33  GLN K 39  
AA9 5 GLU C 52  ? ALA C 57  ? GLU K 46  ALA K 51  
AA9 6 ALA C 64  ? TYR C 66  ? ALA K 58  TYR K 60  
AB1 1 MET D 4   ? THR D 5   ? MET L 5   THR L 6   
AB1 2 VAL D 19  ? ALA D 25  ? VAL L 20  ALA L 26  
AB1 3 ASP D 70  ? ILE D 75  ? ASP L 71  ILE L 76  
AB1 4 PHE D 62  ? SER D 67  ? PHE L 63  SER L 68  
AB2 1 SER D 10  ? ALA D 13  ? SER L 11  ALA L 14  
AB2 2 THR D 103 ? ILE D 107 ? THR L 104 ILE L 108 
AB2 3 THR D 85  ? GLN D 90  ? THR L 86  GLN L 91  
AB2 4 VAL D 33  ? GLN D 38  ? VAL L 34  GLN L 39  
AB2 5 LYS D 45  ? TYR D 49  ? LYS L 46  TYR L 50  
AB2 6 SER D 53  ? LEU D 54  ? SER L 54  LEU L 55  
AB3 1 SER D 10  ? ALA D 13  ? SER L 11  ALA L 14  
AB3 2 THR D 103 ? ILE D 107 ? THR L 104 ILE L 108 
AB3 3 THR D 85  ? GLN D 90  ? THR L 86  GLN L 91  
AB3 4 THR D 98  ? PHE D 99  ? THR L 99  PHE L 100 
AB4 1 SER D 115 ? PHE D 119 ? SER L 116 PHE L 120 
AB4 2 THR D 130 ? PHE D 140 ? THR L 131 PHE L 141 
AB4 3 TYR D 174 ? SER D 183 ? TYR L 175 SER L 184 
AB4 4 SER D 160 ? VAL D 164 ? SER L 161 VAL L 165 
AB5 1 ALA D 154 ? LEU D 155 ? ALA L 155 LEU L 156 
AB5 2 LYS D 146 ? VAL D 151 ? LYS L 147 VAL L 152 
AB5 3 VAL D 192 ? THR D 198 ? VAL L 193 THR L 199 
AB5 4 VAL D 206 ? ASN D 211 ? VAL L 207 ASN L 212 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N TYR A 22  ? N TYR A 22  O HIS A 31  ? O HIS A 31  
AA2 1 2 N VAL B 8   ? N VAL H 8   O ALA B 26  ? O ALA H 26  
AA2 2 3 N LEU B 21  ? N LEU H 21  O MET B 86  ? O MET H 86  
AA2 3 4 O GLN B 85  ? O GLN H 85  N THR B 72  ? N THR H 72  
AA3 1 2 N GLY B 13  ? N GLY H 13  O THR B 124 ? O THR H 124 
AA3 2 3 O THR B 121 ? O THR H 121 N TYR B 97  ? N TYR H 97  
AA3 3 4 O VAL B 96  ? O VAL H 96  N GLN B 42  ? N GLN H 42  
AA3 4 5 N ARG B 41  ? N ARG H 41  O GLU B 49  ? O GLU H 49  
AA3 5 6 N TYR B 53  ? N TYR H 53  O SER B 62  ? O SER H 62  
AA4 1 2 N SER B 134 ? N SER H 134 O LYS B 157 ? O LYS H 157 
AA4 2 3 N VAL B 156 ? N VAL H 156 O LEU B 192 ? O LEU H 192 
AA4 3 4 O VAL B 195 ? O VAL H 195 N HIS B 178 ? N HIS H 178 
AA5 1 2 N SER B 134 ? N SER H 134 O LYS B 157 ? O LYS H 157 
AA5 2 3 N VAL B 156 ? N VAL H 156 O LEU B 192 ? O LEU H 192 
AA5 3 4 O SER B 191 ? O SER H 191 N VAL B 183 ? N VAL H 183 
AA6 1 2 N ALA B 150 ? N ALA H 150 O VAL B 198 ? O VAL H 198 
AA7 1 2 N SER B 167 ? N SER H 167 O ASN B 211 ? O ASN H 211 
AA7 2 3 N CYS B 210 ? N CYS H 210 O LYS B 223 ? O LYS H 223 
AA8 1 2 N GLN C 9   ? N GLN K 3   O SER C 31  ? O SER K 25  
AA8 2 3 N LEU C 26  ? N LEU K 20  O LEU C 87  ? O LEU K 81  
AA8 3 4 O GLN C 88  ? O GLN K 82  N THR C 75  ? N THR K 69  
AA9 1 2 N VAL C 18  ? N VAL K 12  O THR C 124 ? O THR K 118 
AA9 2 3 O THR C 121 ? O THR K 115 N TYR C 100 ? N TYR K 94  
AA9 3 4 O ASP C 105 ? O ASP K 99  N ALA C 39  ? N ALA K 33  
AA9 4 5 N ARG C 44  ? N ARG K 38  O GLU C 52  ? O GLU K 46  
AA9 5 6 N VAL C 56  ? N VAL K 50  O PHE C 65  ? O PHE K 59  
AB1 1 2 N THR D 5   ? N THR L 6   O ARG D 24  ? O ARG L 25  
AB1 2 3 N CYS D 23  ? N CYS L 24  O PHE D 71  ? O PHE L 72  
AB1 3 4 O ASP D 70  ? O ASP L 71  N SER D 67  ? N SER L 68  
AB2 1 2 N LEU D 11  ? N LEU L 12  O GLU D 106 ? O GLU L 107 
AB2 2 3 O THR D 103 ? O THR L 104 N TYR D 86  ? N TYR L 87  
AB2 3 4 O THR D 85  ? O THR L 86  N GLN D 38  ? N GLN L 39  
AB2 4 5 N TRP D 35  ? N TRP L 36  O LEU D 47  ? O LEU L 48  
AB2 5 6 N TYR D 49  ? N TYR L 50  O SER D 53  ? O SER L 54  
AB3 1 2 N LEU D 11  ? N LEU L 12  O GLU D 106 ? O GLU L 107 
AB3 2 3 O THR D 103 ? O THR L 104 N TYR D 86  ? N TYR L 87  
AB3 3 4 N GLN D 90  ? N GLN L 91  O THR D 98  ? O THR L 99  
AB4 1 2 N SER D 115 ? N SER L 116 O ASN D 138 ? O ASN L 139 
AB4 2 3 N PHE D 140 ? N PHE L 141 O TYR D 174 ? O TYR L 175 
AB4 3 4 O THR D 179 ? O THR L 180 N GLN D 161 ? N GLN L 162 
AB5 1 2 O ALA D 154 ? O ALA L 155 N VAL D 151 ? N VAL L 152 
AB5 2 3 N LYS D 150 ? N LYS L 151 O ALA D 194 ? O ALA L 195 
AB5 3 4 N VAL D 197 ? N VAL L 198 O VAL D 206 ? O VAL L 207 
# 
_pdbx_entry_details.entry_id                   9HB3 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LYS A 10  ? ? -169.98 103.96  
2  1 VAL H 51  ? ? -108.90 -60.21  
3  1 ASP H 158 ? ? 60.96   66.96   
4  1 PRO H 161 ? ? -74.20  -157.08 
5  1 SER H 200 ? ? -78.14  -160.04 
6  1 SER H 201 ? ? 66.40   66.50   
7  1 SER K 54  ? ? -161.69 117.36  
8  1 SER L 51  ? ? 57.79   18.12   
9  1 ALA L 52  ? ? 60.86   -0.70   
10 1 SER L 53  ? ? -142.65 -12.71  
11 1 ASN L 140 ? ? 64.13   60.12   
12 1 THR R 102 ? ? 53.95   -131.39 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9HB3 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  . 
_em_3d_fitting_list.pdb_chain_id                  . 
_em_3d_fitting_list.pdb_chain_residue_range       . 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   AlphaFold 
_em_3d_fitting_list.type                          'in silico model' 
_em_3d_fitting_list.accession_code                ? 
_em_3d_fitting_list.initial_refinement_model_id   ? 
# 
_em_3d_reconstruction.entry_id                    9HB3 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.5 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               202513 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 
'Inactive V2R-bril bound to tolvaptan stabillized with anti-BRIL Fab and anti-BRIL Fab Nanobody' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4' 
# 
_em_imaging.entry_id                        9HB3 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             600 
_em_imaging.nominal_defocus_max             1800 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    ? 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        'Quantifoil R0.6/1' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9HB3 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   278 
_em_vitrification.instrument            'LEICA EM GP' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9HB3 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A ARG 1   ? A ARG 1   
2   1 Y 1 A PRO 2   ? A PRO 2   
3   1 Y 1 A SER 3   ? A SER 3   
4   1 Y 1 A SER 24  ? A SER 24  
5   1 Y 1 A GLN 25  ? A GLN 25  
6   1 Y 1 A LYS 26  ? A LYS 26  
7   1 Y 1 A THR 27  ? A THR 27  
8   1 Y 1 A ASN 28  ? A ASN 28  
9   1 Y 1 A LYS 29  ? A LYS 29  
10  1 Y 1 A GLY 57  ? A GLY 57  
11  1 Y 1 H GLU 1   ? B GLU 1   
12  1 Y 1 H ILE 2   ? B ILE 2   
13  1 Y 1 H SER 3   ? B SER 3   
14  1 Y 1 H SER 229 ? B SER 229 
15  1 Y 1 H CYS 230 ? B CYS 230 
16  1 Y 1 H ASP 231 ? B ASP 231 
17  1 Y 1 K ALA -5  ? C ALA 1   
18  1 Y 1 K GLN -4  ? C GLN 2   
19  1 Y 1 K PRO -3  ? C PRO 3   
20  1 Y 1 K ALA -2  ? C ALA 4   
21  1 Y 1 K MET -1  ? C MET 5   
22  1 Y 1 K ALA 0   ? C ALA 6   
23  1 Y 1 K SER 121 ? C SER 127 
24  1 Y 1 K LEU 122 ? C LEU 128 
25  1 Y 1 K GLU 123 ? C GLU 129 
26  1 Y 1 K ASP 124 ? C ASP 130 
27  1 Y 1 K TYR 125 ? C TYR 131 
28  1 Y 1 K LYS 126 ? C LYS 132 
29  1 Y 1 K ASP 127 ? C ASP 133 
30  1 Y 1 K ASP 128 ? C ASP 134 
31  1 Y 1 K LYS 129 ? C LYS 135 
32  1 Y 1 K HIS 130 ? C HIS 136 
33  1 Y 1 K HIS 131 ? C HIS 137 
34  1 Y 1 K HIS 132 ? C HIS 138 
35  1 Y 1 K HIS 133 ? C HIS 139 
36  1 Y 1 K HIS 134 ? C HIS 140 
37  1 Y 1 K HIS 135 ? C HIS 141 
38  1 Y 1 L GLY 214 ? D GLY 213 
39  1 Y 1 L GLU 215 ? D GLU 214 
40  1 Y 1 L CYS 216 ? D CYS 215 
41  1 Y 1 R MET -63 ? E MET 1   
42  1 Y 1 R LYS -62 ? E LYS 2   
43  1 Y 1 R THR -61 ? E THR 3   
44  1 Y 1 R ILE -60 ? E ILE 4   
45  1 Y 1 R ILE -59 ? E ILE 5   
46  1 Y 1 R ALA -58 ? E ALA 6   
47  1 Y 1 R LEU -57 ? E LEU 7   
48  1 Y 1 R SER -56 ? E SER 8   
49  1 Y 1 R TYR -55 ? E TYR 9   
50  1 Y 1 R ILE -54 ? E ILE 10  
51  1 Y 1 R PHE -53 ? E PHE 11  
52  1 Y 1 R CYS -52 ? E CYS 12  
53  1 Y 1 R LEU -51 ? E LEU 13  
54  1 Y 1 R VAL -50 ? E VAL 14  
55  1 Y 1 R PHE -49 ? E PHE 15  
56  1 Y 1 R ALA -48 ? E ALA 16  
57  1 Y 1 R ASP -47 ? E ASP 17  
58  1 Y 1 R TYR -46 ? E TYR 18  
59  1 Y 1 R LYS -45 ? E LYS 19  
60  1 Y 1 R ASP -44 ? E ASP 20  
61  1 Y 1 R ASP -43 ? E ASP 21  
62  1 Y 1 R ASP -42 ? E ASP 22  
63  1 Y 1 R ASP -41 ? E ASP 23  
64  1 Y 1 R ALA -40 ? E ALA 24  
65  1 Y 1 R TRP -39 ? E TRP 25  
66  1 Y 1 R SER -38 ? E SER 26  
67  1 Y 1 R HIS -37 ? E HIS 27  
68  1 Y 1 R PRO -36 ? E PRO 28  
69  1 Y 1 R GLN -35 ? E GLN 29  
70  1 Y 1 R PHE -34 ? E PHE 30  
71  1 Y 1 R GLU -33 ? E GLU 31  
72  1 Y 1 R LYS -32 ? E LYS 32  
73  1 Y 1 R GLY -31 ? E GLY 33  
74  1 Y 1 R GLY -30 ? E GLY 34  
75  1 Y 1 R GLY -29 ? E GLY 35  
76  1 Y 1 R SER -28 ? E SER 36  
77  1 Y 1 R GLY -27 ? E GLY 37  
78  1 Y 1 R GLY -26 ? E GLY 38  
79  1 Y 1 R GLY -25 ? E GLY 39  
80  1 Y 1 R SER -24 ? E SER 40  
81  1 Y 1 R GLY -23 ? E GLY 41  
82  1 Y 1 R GLY -22 ? E GLY 42  
83  1 Y 1 R GLY -21 ? E GLY 43  
84  1 Y 1 R SER -20 ? E SER 44  
85  1 Y 1 R TRP -19 ? E TRP 45  
86  1 Y 1 R SER -18 ? E SER 46  
87  1 Y 1 R HIS -17 ? E HIS 47  
88  1 Y 1 R PRO -16 ? E PRO 48  
89  1 Y 1 R GLN -15 ? E GLN 49  
90  1 Y 1 R PHE -14 ? E PHE 50  
91  1 Y 1 R GLU -13 ? E GLU 51  
92  1 Y 1 R LYS -12 ? E LYS 52  
93  1 Y 1 R LEU -11 ? E LEU 53  
94  1 Y 1 R GLU -10 ? E GLU 54  
95  1 Y 1 R VAL -9  ? E VAL 55  
96  1 Y 1 R LEU -8  ? E LEU 56  
97  1 Y 1 R GLN -7  ? E GLN 57  
98  1 Y 1 R GLY -6  ? E GLY 58  
99  1 Y 1 R PRO -5  ? E PRO 59  
100 1 Y 1 R ASP -4  ? E ASP 60  
101 1 Y 1 R TYR -3  ? E TYR 61  
102 1 Y 1 R LYS -2  ? E LYS 62  
103 1 Y 1 R ASP -1  ? E ASP 63  
104 1 Y 1 R ASP 0   ? E ASP 64  
105 1 Y 1 R ASP 1   ? E ASP 65  
106 1 Y 1 R ASP 2   ? E ASP 66  
107 1 Y 1 R ALA 3   ? E ALA 67  
108 1 Y 1 R ALA 4   ? E ALA 68  
109 1 Y 1 R SER 5   ? E SER 69  
110 1 Y 1 R THR 6   ? E THR 70  
111 1 Y 1 R THR 7   ? E THR 71  
112 1 Y 1 R SER 8   ? E SER 72  
113 1 Y 1 R ALA 9   ? E ALA 73  
114 1 Y 1 R VAL 10  ? E VAL 74  
115 1 Y 1 R PRO 11  ? E PRO 75  
116 1 Y 1 R GLY 12  ? E GLY 76  
117 1 Y 1 R HIS 13  ? E HIS 77  
118 1 Y 1 R PRO 14  ? E PRO 78  
119 1 Y 1 R SER 15  ? E SER 79  
120 1 Y 1 R LEU 16  ? E LEU 80  
121 1 Y 1 R PRO 17  ? E PRO 81  
122 1 Y 1 R SER 18  ? E SER 82  
123 1 Y 1 R LEU 19  ? E LEU 83  
124 1 Y 1 R PRO 20  ? E PRO 84  
125 1 Y 1 R SER 21  ? E SER 85  
126 1 Y 1 R GLN 22  ? E GLN 86  
127 1 Y 1 R SER 23  ? E SER 87  
128 1 Y 1 R SER 24  ? E SER 88  
129 1 Y 1 R GLN 25  ? E GLN 89  
130 1 Y 1 R GLU 26  ? E GLU 90  
131 1 Y 1 R ARG 27  ? E ARG 91  
132 1 Y 1 R PRO 28  ? E PRO 92  
133 1 Y 1 R LEU 29  ? E LEU 93  
134 1 Y 1 R ASP 30  ? E ASP 94  
135 1 Y 1 R THR 31  ? E THR 95  
136 1 Y 1 R ARG 32  ? E ARG 96  
137 1 Y 1 R ASP 33  ? E ASP 97  
138 1 Y 1 R PRO 34  ? E PRO 98  
139 1 Y 1 R PRO 108 ? E PRO 172 
140 1 Y 1 R MET 145 ? E MET 209 
141 1 Y 1 R LEU 146 ? E LEU 210 
142 1 Y 1 R ALA 147 ? E ALA 211 
143 1 Y 1 R TYR 148 ? E TYR 212 
144 1 Y 1 R ARG 149 ? E ARG 213 
145 1 Y 1 R HIS 150 ? E HIS 214 
146 1 Y 1 R GLY 151 ? E GLY 215 
147 1 Y 1 R SER 152 ? E SER 216 
148 1 Y 1 R GLY 153 ? E GLY 217 
149 1 Y 1 R ALA 154 ? E ALA 218 
150 1 Y 1 R HIS 155 ? E HIS 219 
151 1 Y 1 R TRP 156 ? E TRP 220 
152 1 Y 1 R ARG 181 ? E ARG 245 
153 1 Y 1 R ASN 182 ? E ASN 246 
154 1 Y 1 R VAL 183 ? E VAL 247 
155 1 Y 1 R GLU 184 ? E GLU 248 
156 1 Y 1 R GLY 185 ? E GLY 249 
157 1 Y 1 R GLY 186 ? E GLY 250 
158 1 Y 1 R SER 187 ? E SER 251 
159 1 Y 1 R GLY 188 ? E GLY 252 
160 1 Y 1 R VAL 189 ? E VAL 253 
161 1 Y 1 R ALA 197 ? E ALA 261 
162 1 Y 1 R GLU 198 ? E GLU 262 
163 1 Y 1 R PRO 199 ? E PRO 263 
164 1 Y 1 R SER 235 ? E SER 299 
165 1 Y 1 R LEU 236 ? E LEU 300 
166 1 Y 1 R VAL 237 ? E VAL 301 
167 1 Y 1 R PRO 238 ? E PRO 302 
168 1 Y 1 R GLY 239 ? E GLY 303 
169 1 Y 1 R PRO 240 ? E PRO 304 
170 1 Y 1 R SER 241 ? E SER 305 
171 1 Y 1 R GLU 242 ? E GLU 306 
172 1 Y 1 R ARG 243 ? E ARG 307 
173 1 Y 1 R PRO 244 ? E PRO 308 
174 1 Y 1 R GLY 245 ? E GLY 309 
175 1 Y 1 R GLY 246 ? E GLY 310 
176 1 Y 1 R ARG 247 ? E ARG 311 
177 1 Y 1 R ARG 248 ? E ARG 312 
178 1 Y 1 R ARG 249 ? E ARG 313 
179 1 Y 1 R GLY 250 ? E GLY 314 
180 1 Y 1 R ARG 251 ? E ARG 315 
181 1 Y 1 R ARG 252 ? E ARG 316 
182 1 Y 1 R THR 253 ? E THR 317 
183 1 Y 1 R GLY 254 ? E GLY 318 
184 1 Y 1 R SER 255 ? E SER 319 
185 1 Y 1 R PRO 256 ? E PRO 320 
186 1 Y 1 R GLY 257 ? E GLY 321 
187 1 Y 1 R GLU 258 ? E GLU 322 
188 1 Y 1 R GLY 259 ? E GLY 323 
189 1 Y 1 R ALA 260 ? E ALA 324 
190 1 Y 1 R HIS 261 ? E HIS 325 
191 1 Y 1 R VAL 262 ? E VAL 326 
192 1 Y 1 R SER 263 ? E SER 327 
193 1 Y 1 R GLU 299 ? E GLU 363 
194 1 Y 1 R ALA 300 ? E ALA 364 
195 1 Y 1 R PRO 301 ? E PRO 365 
196 1 Y 1 R LEU 302 ? E LEU 366 
197 1 Y 1 R GLU 303 ? E GLU 367 
198 1 Y 1 R GLY 304 ? E GLY 368 
199 1 Y 1 R ALA 305 ? E ALA 369 
200 1 Y 1 R SER 466 ? E SER 402 
201 1 Y 1 R LEU 467 ? E LEU 403 
202 1 Y 1 R LEU 468 ? E LEU 404 
203 1 Y 1 R CYS 469 ? E CYS 405 
204 1 Y 1 R CYS 470 ? E CYS 406 
205 1 Y 1 R ALA 471 ? E ALA 407 
206 1 Y 1 R ARG 472 ? E ARG 408 
207 1 Y 1 R GLY 473 ? E GLY 409 
208 1 Y 1 R ARG 474 ? E ARG 410 
209 1 Y 1 R THR 475 ? E THR 411 
210 1 Y 1 R PRO 476 ? E PRO 412 
211 1 Y 1 R PRO 477 ? E PRO 413 
212 1 Y 1 R SER 478 ? E SER 414 
213 1 Y 1 R LEU 479 ? E LEU 415 
214 1 Y 1 R GLY 480 ? E GLY 416 
215 1 Y 1 R PRO 481 ? E PRO 417 
216 1 Y 1 R GLN 482 ? E GLN 418 
217 1 Y 1 R ASP 483 ? E ASP 419 
218 1 Y 1 R GLU 484 ? E GLU 420 
219 1 Y 1 R SER 485 ? E SER 421 
220 1 Y 1 R CYS 486 ? E CYS 422 
221 1 Y 1 R THR 487 ? E THR 423 
222 1 Y 1 R THR 488 ? E THR 424 
223 1 Y 1 R ALA 489 ? E ALA 425 
224 1 Y 1 R SER 490 ? E SER 426 
225 1 Y 1 R SER 491 ? E SER 427 
226 1 Y 1 R SER 492 ? E SER 428 
227 1 Y 1 R LEU 493 ? E LEU 429 
228 1 Y 1 R ALA 494 ? E ALA 430 
229 1 Y 1 R LYS 495 ? E LYS 431 
230 1 Y 1 R ASP 496 ? E ASP 432 
231 1 Y 1 R THR 497 ? E THR 433 
232 1 Y 1 R SER 498 ? E SER 434 
233 1 Y 1 R SER 499 ? E SER 435 
234 1 Y 1 R PRO 550 ? E PRO 486 
235 1 Y 1 R LYS 551 ? E LYS 487 
236 1 Y 1 R LEU 552 ? E LEU 488 
237 1 Y 1 R GLU 553 ? E GLU 489 
238 1 Y 1 R ASP 554 ? E ASP 490 
239 1 Y 1 R LYS 555 ? E LYS 491 
240 1 Y 1 R SER 556 ? E SER 492 
241 1 Y 1 R PRO 557 ? E PRO 493 
242 1 Y 1 R ASP 558 ? E ASP 494 
243 1 Y 1 R SER 559 ? E SER 495 
244 1 Y 1 R PRO 560 ? E PRO 496 
245 1 Y 1 R GLU 561 ? E GLU 497 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-11-05 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9HB3 
_em_admin.last_update        2025-06-04 
_em_admin.map_release_date   2025-06-04 
_em_admin.title              
'cryo-EM structure of inactive human arginine-vasopressin (AVP) V2 receptor (V2R) with Mambaquaretin1 K39A (MQK39A)' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.115 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         80 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? Topaz     ?     
'IMAGE ACQUISITION'             ? 2  ? ? 1 EPU       3.6   
MASKING                         ? 3  ? ? ? ?         ?     
'CTF CORRECTION'                ? 4  1 ? ? cryoSPARC 4.5.1 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?         ?     
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?         ?     
'MODEL FITTING'                 ? 7  ? 1 ? Coot      ?     
OTHER                           ? 8  ? ? ? ?         ?     
'MODEL REFINEMENT'              ? 9  ? 1 ? Rosetta   ?     
'MODEL REFINEMENT'              ? 10 ? 1 ? PHENIX    ?     
'INITIAL EULER ASSIGNMENT'      ? 11 1 ? ? cryoSPARC 4.5.1 
'FINAL EULER ASSIGNMENT'        ? 12 1 ? ? cryoSPARC 4.5.1 
CLASSIFICATION                  ? 13 1 ? ? RELION    4     
RECONSTRUCTION                  ? 14 1 ? ? cryoSPARC 4.5.1 
'VOLUME SELECTION'              ? 15 1 1 1 ?         ?     
'SERIES ALIGNMENT'              ? 16 1 1 1 ?         ?     
'MOLECULAR REPLACEMENT'         ? 17 1 1 1 ?         ?     
'LATTICE DISTORTION CORRECTION' ? 18 1 1 1 ?         ?     
'SYMMETRY DETERMINATION'        ? 19 1 1 1 ?         ?     
'CRYSTALLOGRAPHY MERGING'       ? 20 1 1 1 ?         ?     
# 
_em_specimen.concentration           22 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Agence Nationale de la Recherche (ANR)'               France           ANR-19-CE11-0014 1 
'Agence Nationale de la Recherche (ANR)'               France           ANR-22-CE44-0021 2 
'H2020 Marie Curie Actions of the European Commission' 'European Union' 101063049_3D-V2R 3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9HB3 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . PHE A 1 4   ? 157.702 181.697 89.902  1.00 13.90  ? 4   PHE A N   1 
ATOM 2    C CA  . PHE A 1 4   ? 157.437 180.521 90.718  1.00 14.26  ? 4   PHE A CA  1 
ATOM 3    C C   . PHE A 1 4   ? 156.077 180.586 91.399  1.00 12.20  ? 4   PHE A C   1 
ATOM 4    O O   . PHE A 1 4   ? 155.587 179.566 91.889  1.00 12.96  ? 4   PHE A O   1 
ATOM 5    C CB  . PHE A 1 4   ? 158.546 180.327 91.761  1.00 15.42  ? 4   PHE A CB  1 
ATOM 6    C CG  . PHE A 1 4   ? 158.430 181.212 92.970  1.00 12.49  ? 4   PHE A CG  1 
ATOM 7    C CD1 . PHE A 1 4   ? 157.705 180.808 94.080  1.00 13.72  ? 4   PHE A CD1 1 
ATOM 8    C CD2 . PHE A 1 4   ? 159.086 182.427 93.015  1.00 17.10  ? 4   PHE A CD2 1 
ATOM 9    C CE1 . PHE A 1 4   ? 157.611 181.615 95.198  1.00 17.00  ? 4   PHE A CE1 1 
ATOM 10   C CE2 . PHE A 1 4   ? 159.001 183.235 94.132  1.00 20.60  ? 4   PHE A CE2 1 
ATOM 11   C CZ  . PHE A 1 4   ? 158.262 182.829 95.224  1.00 18.24  ? 4   PHE A CZ  1 
ATOM 12   N N   . CYS A 1 5   ? 155.468 181.784 91.465  1.00 11.78  ? 5   CYS A N   1 
ATOM 13   C CA  . CYS A 1 5   ? 154.099 181.883 91.930  1.00 11.04  ? 5   CYS A CA  1 
ATOM 14   C C   . CYS A 1 5   ? 153.208 181.132 90.996  1.00 11.96  ? 5   CYS A C   1 
ATOM 15   O O   . CYS A 1 5   ? 152.015 180.928 91.252  1.00 12.82  ? 5   CYS A O   1 
ATOM 16   C CB  . CYS A 1 5   ? 153.645 183.344 92.001  1.00 11.75  ? 5   CYS A CB  1 
ATOM 17   S SG  . CYS A 1 5   ? 154.661 184.371 93.079  1.00 12.09  ? 5   CYS A SG  1 
ATOM 18   N N   . ASN A 1 6   ? 153.781 180.731 89.867  1.00 12.36  ? 6   ASN A N   1 
ATOM 19   C CA  . ASN A 1 6   ? 153.081 180.020 88.848  1.00 13.66  ? 6   ASN A CA  1 
ATOM 20   C C   . ASN A 1 6   ? 153.508 178.562 88.816  1.00 14.82  ? 6   ASN A C   1 
ATOM 21   O O   . ASN A 1 6   ? 153.436 177.908 87.783  1.00 17.53  ? 6   ASN A O   1 
ATOM 22   C CB  . ASN A 1 6   ? 153.287 180.750 87.517  1.00 16.57  ? 6   ASN A CB  1 
ATOM 23   C CG  . ASN A 1 6   ? 152.975 182.228 87.650  1.00 16.49  ? 6   ASN A CG  1 
ATOM 24   O OD1 . ASN A 1 6   ? 152.455 182.664 88.679  1.00 18.50  ? 6   ASN A OD1 1 
ATOM 25   N ND2 . ASN A 1 6   ? 153.266 182.999 86.615  1.00 19.78  ? 6   ASN A ND2 1 
ATOM 26   N N   . LEU A 1 7   ? 153.977 178.025 89.979  1.00 13.15  ? 7   LEU A N   1 
ATOM 27   C CA  . LEU A 1 7   ? 154.308 176.601 90.099  1.00 13.34  ? 7   LEU A CA  1 
ATOM 28   C C   . LEU A 1 7   ? 153.217 175.858 90.868  1.00 12.76  ? 7   LEU A C   1 
ATOM 29   O O   . LEU A 1 7   ? 152.949 176.217 92.020  1.00 13.24  ? 7   LEU A O   1 
ATOM 30   C CB  . LEU A 1 7   ? 155.666 176.431 90.787  1.00 13.96  ? 7   LEU A CB  1 
ATOM 31   C CG  . LEU A 1 7   ? 156.893 176.806 89.946  1.00 15.70  ? 7   LEU A CG  1 
ATOM 32   C CD1 . LEU A 1 7   ? 158.177 176.438 90.671  1.00 17.94  ? 7   LEU A CD1 1 
ATOM 33   C CD2 . LEU A 1 7   ? 156.824 176.119 88.593  1.00 20.15  ? 7   LEU A CD2 1 
ATOM 34   N N   . PRO A 1 8   ? 152.538 174.814 90.284  1.00 14.02  ? 8   PRO A N   1 
ATOM 35   C CA  . PRO A 1 8   ? 151.384 174.183 90.959  1.00 13.91  ? 8   PRO A CA  1 
ATOM 36   C C   . PRO A 1 8   ? 151.743 173.497 92.277  1.00 13.71  ? 8   PRO A C   1 
ATOM 37   O O   . PRO A 1 8   ? 152.919 173.531 92.653  1.00 15.09  ? 8   PRO A O   1 
ATOM 38   C CB  . PRO A 1 8   ? 150.902 173.176 89.894  1.00 16.62  ? 8   PRO A CB  1 
ATOM 39   C CG  . PRO A 1 8   ? 151.378 173.802 88.597  1.00 18.49  ? 8   PRO A CG  1 
ATOM 40   C CD  . PRO A 1 8   ? 152.749 174.274 88.940  1.00 16.49  ? 8   PRO A CD  1 
ATOM 41   N N   . VAL A 1 9   ? 150.775 172.898 92.991  1.00 12.83  ? 9   VAL A N   1 
ATOM 42   C CA  . VAL A 1 9   ? 150.967 172.354 94.318  1.00 12.91  ? 9   VAL A CA  1 
ATOM 43   C C   . VAL A 1 9   ? 150.759 170.858 94.290  1.00 12.04  ? 9   VAL A C   1 
ATOM 44   O O   . VAL A 1 9   ? 150.237 170.300 93.330  1.00 13.07  ? 9   VAL A O   1 
ATOM 45   C CB  . VAL A 1 9   ? 150.018 172.985 95.349  1.00 14.22  ? 9   VAL A CB  1 
ATOM 46   C CG1 . VAL A 1 9   ? 150.289 174.478 95.486  1.00 15.76  ? 9   VAL A CG1 1 
ATOM 47   C CG2 . VAL A 1 9   ? 148.569 172.756 94.938  1.00 15.49  ? 9   VAL A CG2 1 
ATOM 48   N N   . LYS A 1 10  ? 151.182 170.201 95.354  1.00 12.80  ? 10  LYS A N   1 
ATOM 49   C CA  . LYS A 1 10  ? 151.023 168.790 95.516  1.00 13.31  ? 10  LYS A CA  1 
ATOM 50   C C   . LYS A 1 10  ? 151.431 168.634 96.963  1.00 12.76  ? 10  LYS A C   1 
ATOM 51   O O   . LYS A 1 10  ? 152.625 168.825 97.235  1.00 13.16  ? 10  LYS A O   1 
ATOM 52   C CB  . LYS A 1 10  ? 151.944 168.061 94.545  1.00 15.07  ? 10  LYS A CB  1 
ATOM 53   C CG  . LYS A 1 10  ? 151.330 167.587 93.235  1.00 17.20  ? 10  LYS A CG  1 
ATOM 54   C CD  . LYS A 1 10  ? 150.005 166.863 93.418  1.00 20.46  ? 10  LYS A CD  1 
ATOM 55   C CE  . LYS A 1 10  ? 149.344 166.637 92.093  1.00 28.39  ? 10  LYS A CE  1 
ATOM 56   N NZ  . LYS A 1 10  ? 150.271 165.979 91.164  1.00 29.99  ? 10  LYS A NZ  1 
ATOM 57   N N   . PRO A 1 11  ? 150.507 168.444 97.928  1.00 14.02  ? 11  PRO A N   1 
ATOM 58   C CA  . PRO A 1 11  ? 150.947 168.433 99.325  1.00 14.29  ? 11  PRO A CA  1 
ATOM 59   C C   . PRO A 1 11  ? 152.093 167.448 99.486  1.00 14.78  ? 11  PRO A C   1 
ATOM 60   O O   . PRO A 1 11  ? 152.427 166.674 98.581  1.00 15.23  ? 11  PRO A O   1 
ATOM 61   C CB  . PRO A 1 11  ? 149.674 168.036 100.104 1.00 17.86  ? 11  PRO A CB  1 
ATOM 62   C CG  . PRO A 1 11  ? 148.692 167.544 99.056  1.00 21.76  ? 11  PRO A CG  1 
ATOM 63   C CD  . PRO A 1 11  ? 149.061 168.226 97.781  1.00 17.89  ? 11  PRO A CD  1 
ATOM 64   N N   . GLY A 1 12  ? 152.779 167.510 100.601 1.00 17.01  ? 12  GLY A N   1 
ATOM 65   C CA  . GLY A 1 12  ? 153.931 166.670 100.732 1.00 18.60  ? 12  GLY A CA  1 
ATOM 66   C C   . GLY A 1 12  ? 153.530 165.228 100.933 1.00 15.42  ? 12  GLY A C   1 
ATOM 67   O O   . GLY A 1 12  ? 152.786 164.932 101.862 1.00 20.13  ? 12  GLY A O   1 
ATOM 68   N N   . PRO A 1 13  ? 154.052 164.307 100.103 1.00 20.71  ? 13  PRO A N   1 
ATOM 69   C CA  . PRO A 1 13  ? 153.774 162.872 100.300 1.00 21.57  ? 13  PRO A CA  1 
ATOM 70   C C   . PRO A 1 13  ? 153.938 162.430 101.733 1.00 21.04  ? 13  PRO A C   1 
ATOM 71   O O   . PRO A 1 13  ? 153.303 161.459 102.157 1.00 22.30  ? 13  PRO A O   1 
ATOM 72   C CB  . PRO A 1 13  ? 154.801 162.193 99.379  1.00 24.33  ? 13  PRO A CB  1 
ATOM 73   C CG  . PRO A 1 13  ? 155.834 163.231 99.112  1.00 23.19  ? 13  PRO A CG  1 
ATOM 74   C CD  . PRO A 1 13  ? 155.111 164.529 99.115  1.00 17.52  ? 13  PRO A CD  1 
ATOM 75   N N   . CYS A 1 14  ? 154.778 163.125 102.494 1.00 19.68  ? 14  CYS A N   1 
ATOM 76   C CA  . CYS A 1 14  ? 154.960 162.845 103.907 1.00 18.12  ? 14  CYS A CA  1 
ATOM 77   C C   . CYS A 1 14  ? 153.733 163.341 104.653 1.00 18.29  ? 14  CYS A C   1 
ATOM 78   O O   . CYS A 1 14  ? 153.521 164.554 104.759 1.00 21.88  ? 14  CYS A O   1 
ATOM 79   C CB  . CYS A 1 14  ? 156.231 163.524 104.409 1.00 17.51  ? 14  CYS A CB  1 
ATOM 80   S SG  . CYS A 1 14  ? 157.649 163.234 103.339 1.00 21.14  ? 14  CYS A SG  1 
ATOM 81   N N   . ASN A 1 15  ? 152.904 162.418 105.133 1.00 18.27  ? 15  ASN A N   1 
ATOM 82   C CA  . ASN A 1 15  ? 151.721 162.807 105.893 1.00 20.49  ? 15  ASN A CA  1 
ATOM 83   C C   . ASN A 1 15  ? 152.104 163.757 107.023 1.00 23.29  ? 15  ASN A C   1 
ATOM 84   O O   . ASN A 1 15  ? 152.862 163.397 107.926 1.00 23.99  ? 15  ASN A O   1 
ATOM 85   C CB  . ASN A 1 15  ? 151.006 161.574 106.453 1.00 30.00  ? 15  ASN A CB  1 
ATOM 86   C CG  . ASN A 1 15  ? 149.721 161.931 107.179 1.00 30.00  ? 15  ASN A CG  1 
ATOM 87   O OD1 . ASN A 1 15  ? 149.155 163.005 106.967 1.00 30.00  ? 15  ASN A OD1 1 
ATOM 88   N ND2 . ASN A 1 15  ? 149.258 161.038 108.045 1.00 30.00  ? 15  ASN A ND2 1 
ATOM 89   N N   . GLY A 1 16  ? 151.577 164.975 106.961 1.00 19.80  ? 16  GLY A N   1 
ATOM 90   C CA  . GLY A 1 16  ? 151.946 166.015 107.907 1.00 20.73  ? 16  GLY A CA  1 
ATOM 91   C C   . GLY A 1 16  ? 150.979 167.169 107.794 1.00 23.77  ? 16  GLY A C   1 
ATOM 92   O O   . GLY A 1 16  ? 150.143 167.221 106.887 1.00 23.79  ? 16  GLY A O   1 
ATOM 93   N N   . PHE A 1 17  ? 151.098 168.096 108.737 1.00 30.81  ? 17  PHE A N   1 
ATOM 94   C CA  . PHE A 1 17  ? 150.126 169.177 108.854 1.00 30.34  ? 17  PHE A CA  1 
ATOM 95   C C   . PHE A 1 17  ? 150.821 170.520 109.073 1.00 29.17  ? 17  PHE A C   1 
ATOM 96   O O   . PHE A 1 17  ? 150.450 171.307 109.947 1.00 39.72  ? 17  PHE A O   1 
ATOM 97   C CB  . PHE A 1 17  ? 149.125 168.868 109.962 1.00 35.32  ? 17  PHE A CB  1 
ATOM 98   C CG  . PHE A 1 17  ? 148.338 167.613 109.729 1.00 38.94  ? 17  PHE A CG  1 
ATOM 99   C CD1 . PHE A 1 17  ? 147.168 167.640 108.992 1.00 59.76  ? 17  PHE A CD1 1 
ATOM 100  C CD2 . PHE A 1 17  ? 148.772 166.404 110.243 1.00 40.77  ? 17  PHE A CD2 1 
ATOM 101  C CE1 . PHE A 1 17  ? 146.446 166.492 108.777 1.00 54.91  ? 17  PHE A CE1 1 
ATOM 102  C CE2 . PHE A 1 17  ? 148.053 165.251 110.029 1.00 61.20  ? 17  PHE A CE2 1 
ATOM 103  C CZ  . PHE A 1 17  ? 146.888 165.295 109.296 1.00 68.26  ? 17  PHE A CZ  1 
ATOM 104  N N   . PHE A 1 18  ? 151.840 170.806 108.271 1.00 21.74  ? 18  PHE A N   1 
ATOM 105  C CA  . PHE A 1 18  ? 152.444 172.130 108.307 1.00 22.22  ? 18  PHE A CA  1 
ATOM 106  C C   . PHE A 1 18  ? 151.479 173.142 107.708 1.00 20.44  ? 18  PHE A C   1 
ATOM 107  O O   . PHE A 1 18  ? 150.774 172.848 106.740 1.00 23.41  ? 18  PHE A O   1 
ATOM 108  C CB  . PHE A 1 18  ? 153.766 172.152 107.538 1.00 30.00  ? 18  PHE A CB  1 
ATOM 109  C CG  . PHE A 1 18  ? 154.866 171.369 108.190 1.00 30.00  ? 18  PHE A CG  1 
ATOM 110  C CD1 . PHE A 1 18  ? 154.872 169.987 108.141 1.00 30.00  ? 18  PHE A CD1 1 
ATOM 111  C CD2 . PHE A 1 18  ? 155.904 172.015 108.835 1.00 30.00  ? 18  PHE A CD2 1 
ATOM 112  C CE1 . PHE A 1 18  ? 155.887 169.263 108.730 1.00 30.00  ? 18  PHE A CE1 1 
ATOM 113  C CE2 . PHE A 1 18  ? 156.922 171.298 109.428 1.00 30.00  ? 18  PHE A CE2 1 
ATOM 114  C CZ  . PHE A 1 18  ? 156.913 169.919 109.376 1.00 30.00  ? 18  PHE A CZ  1 
ATOM 115  N N   . SER A 1 19  ? 151.415 174.324 108.310 1.00 18.90  ? 19  SER A N   1 
ATOM 116  C CA  . SER A 1 19  ? 150.689 175.419 107.688 1.00 16.81  ? 19  SER A CA  1 
ATOM 117  C C   . SER A 1 19  ? 151.476 175.957 106.504 1.00 15.70  ? 19  SER A C   1 
ATOM 118  O O   . SER A 1 19  ? 152.705 176.044 106.546 1.00 18.18  ? 19  SER A O   1 
ATOM 119  C CB  . SER A 1 19  ? 150.439 176.539 108.695 1.00 19.53  ? 19  SER A CB  1 
ATOM 120  O OG  . SER A 1 19  ? 149.826 177.650 108.063 1.00 24.67  ? 19  SER A OG  1 
ATOM 121  N N   . ALA A 1 20  ? 150.772 176.332 105.447 1.00 12.69  ? 20  ALA A N   1 
ATOM 122  C CA  . ALA A 1 20  ? 151.456 176.969 104.334 1.00 12.16  ? 20  ALA A CA  1 
ATOM 123  C C   . ALA A 1 20  ? 150.450 177.789 103.550 1.00 10.92  ? 20  ALA A C   1 
ATOM 124  O O   . ALA A 1 20  ? 149.239 177.659 103.727 1.00 11.30  ? 20  ALA A O   1 
ATOM 125  C CB  . ALA A 1 20  ? 152.153 175.944 103.440 1.00 14.23  ? 20  ALA A CB  1 
ATOM 126  N N   . PHE A 1 21  ? 150.971 178.659 102.694 1.00 10.13  ? 21  PHE A N   1 
ATOM 127  C CA  . PHE A 1 21  ? 150.142 179.463 101.814 1.00 9.77   ? 21  PHE A CA  1 
ATOM 128  C C   . PHE A 1 21  ? 150.715 179.424 100.404 1.00 9.27   ? 21  PHE A C   1 
ATOM 129  O O   . PHE A 1 21  ? 151.923 179.263 100.206 1.00 9.99   ? 21  PHE A O   1 
ATOM 130  C CB  . PHE A 1 21  ? 150.028 180.899 102.332 1.00 10.83  ? 21  PHE A CB  1 
ATOM 131  C CG  . PHE A 1 21  ? 149.624 180.979 103.773 1.00 10.72  ? 21  PHE A CG  1 
ATOM 132  C CD1 . PHE A 1 21  ? 150.579 180.932 104.769 1.00 12.33  ? 21  PHE A CD1 1 
ATOM 133  C CD2 . PHE A 1 21  ? 148.297 181.070 104.132 1.00 11.44  ? 21  PHE A CD2 1 
ATOM 134  C CE1 . PHE A 1 21  ? 150.219 180.991 106.093 1.00 13.55  ? 21  PHE A CE1 1 
ATOM 135  C CE2 . PHE A 1 21  ? 147.928 181.130 105.457 1.00 13.57  ? 21  PHE A CE2 1 
ATOM 136  C CZ  . PHE A 1 21  ? 148.892 181.092 106.439 1.00 13.66  ? 21  PHE A CZ  1 
ATOM 137  N N   . TYR A 1 22  ? 149.830 179.563 99.423  1.00 9.55   ? 22  TYR A N   1 
ATOM 138  C CA  . TYR A 1 22  ? 150.208 179.394 98.028  1.00 9.48   ? 22  TYR A CA  1 
ATOM 139  C C   . TYR A 1 22  ? 149.384 180.326 97.149  1.00 9.08   ? 22  TYR A C   1 
ATOM 140  O O   . TYR A 1 22  ? 148.267 180.709 97.507  1.00 10.03  ? 22  TYR A O   1 
ATOM 141  C CB  . TYR A 1 22  ? 150.016 177.949 97.563  1.00 10.20  ? 22  TYR A CB  1 
ATOM 142  N N   . TYR A 1 23  ? 149.942 180.695 96.000  1.00 9.44   ? 23  TYR A N   1 
ATOM 143  C CA  . TYR A 1 23  ? 149.239 181.610 95.090  1.00 9.91   ? 23  TYR A CA  1 
ATOM 144  C C   . TYR A 1 23  ? 148.136 180.851 94.350  1.00 10.34  ? 23  TYR A C   1 
ATOM 145  O O   . TYR A 1 23  ? 148.112 180.825 93.114  1.00 11.04  ? 23  TYR A O   1 
ATOM 146  C CB  . TYR A 1 23  ? 150.211 182.262 94.092  1.00 10.63  ? 23  TYR A CB  1 
ATOM 147  C CG  . TYR A 1 23  ? 149.660 183.499 93.400  1.00 11.45  ? 23  TYR A CG  1 
ATOM 148  C CD1 . TYR A 1 23  ? 148.745 184.327 94.039  1.00 11.91  ? 23  TYR A CD1 1 
ATOM 149  C CD2 . TYR A 1 23  ? 150.050 183.834 92.108  1.00 11.97  ? 23  TYR A CD2 1 
ATOM 150  C CE1 . TYR A 1 23  ? 148.237 185.456 93.415  1.00 12.72  ? 23  TYR A CE1 1 
ATOM 151  C CE2 . TYR A 1 23  ? 149.547 184.961 91.475  1.00 12.78  ? 23  TYR A CE2 1 
ATOM 152  C CZ  . TYR A 1 23  ? 148.641 185.767 92.134  1.00 13.15  ? 23  TYR A CZ  1 
ATOM 153  O OH  . TYR A 1 23  ? 148.139 186.884 91.513  1.00 15.42  ? 23  TYR A OH  1 
ATOM 154  N N   . CYS A 1 30  ? 146.219 184.540 97.201  1.00 10.63  ? 30  CYS A N   1 
ATOM 155  C CA  . CYS A 1 30  ? 146.882 183.589 98.082  1.00 10.12  ? 30  CYS A CA  1 
ATOM 156  C C   . CYS A 1 30  ? 145.859 182.881 98.960  1.00 10.34  ? 30  CYS A C   1 
ATOM 157  O O   . CYS A 1 30  ? 144.925 183.504 99.470  1.00 11.73  ? 30  CYS A O   1 
ATOM 158  C CB  . CYS A 1 30  ? 147.923 184.289 98.951  1.00 11.52  ? 30  CYS A CB  1 
ATOM 159  N N   . HIS A 1 31  ? 146.043 181.574 99.127  1.00 10.13  ? 31  HIS A N   1 
ATOM 160  C CA  . HIS A 1 31  ? 145.169 180.759 99.955  1.00 10.41  ? 31  HIS A CA  1 
ATOM 161  C C   . HIS A 1 31  ? 146.008 179.813 100.798 1.00 10.04  ? 31  HIS A C   1 
ATOM 162  O O   . HIS A 1 31  ? 147.104 179.405 100.405 1.00 10.95  ? 31  HIS A O   1 
ATOM 163  C CB  . HIS A 1 31  ? 144.170 179.959 99.110  1.00 11.45  ? 31  HIS A CB  1 
ATOM 164  C CG  . HIS A 1 31  ? 143.284 180.812 98.261  1.00 11.96  ? 31  HIS A CG  1 
ATOM 165  N ND1 . HIS A 1 31  ? 142.100 181.344 98.722  1.00 13.31  ? 31  HIS A ND1 1 
ATOM 166  C CD2 . HIS A 1 31  ? 143.411 181.229 96.979  1.00 13.02  ? 31  HIS A CD2 1 
ATOM 167  C CE1 . HIS A 1 31  ? 141.535 182.052 97.761  1.00 14.11  ? 31  HIS A CE1 1 
ATOM 168  N NE2 . HIS A 1 31  ? 142.310 181.999 96.693  1.00 13.74  ? 31  HIS A NE2 1 
ATOM 169  N N   . SER A 1 32  ? 145.477 179.467 101.961 1.00 11.22  ? 32  SER A N   1 
ATOM 170  C CA  . SER A 1 32  ? 146.175 178.549 102.838 1.00 11.80  ? 32  SER A CA  1 
ATOM 171  C C   . SER A 1 32  ? 146.001 177.115 102.360 1.00 11.43  ? 32  SER A C   1 
ATOM 172  O O   . SER A 1 32  ? 145.055 176.772 101.643 1.00 12.60  ? 32  SER A O   1 
ATOM 173  C CB  . SER A 1 32  ? 145.673 178.683 104.275 1.00 12.45  ? 32  SER A CB  1 
ATOM 174  N N   . PHE A 1 33  ? 146.949 176.278 102.765 1.00 11.82  ? 33  PHE A N   1 
ATOM 175  C CA  . PHE A 1 33  ? 146.869 174.844 102.537 1.00 12.47  ? 33  PHE A CA  1 
ATOM 176  C C   . PHE A 1 33  ? 147.749 174.147 103.563 1.00 13.28  ? 33  PHE A C   1 
ATOM 177  O O   . PHE A 1 33  ? 148.488 174.777 104.327 1.00 14.54  ? 33  PHE A O   1 
ATOM 178  C CB  . PHE A 1 33  ? 147.278 174.469 101.109 1.00 12.28  ? 33  PHE A CB  1 
ATOM 179  C CG  . PHE A 1 33  ? 148.759 174.470 100.879 1.00 11.11  ? 33  PHE A CG  1 
ATOM 180  C CD1 . PHE A 1 33  ? 149.411 175.630 100.500 1.00 11.85  ? 33  PHE A CD1 1 
ATOM 181  C CD2 . PHE A 1 33  ? 149.498 173.306 101.024 1.00 11.49  ? 33  PHE A CD2 1 
ATOM 182  C CE1 . PHE A 1 33  ? 150.771 175.634 100.278 1.00 11.62  ? 33  PHE A CE1 1 
ATOM 183  C CE2 . PHE A 1 33  ? 150.859 173.303 100.810 1.00 11.12  ? 33  PHE A CE2 1 
ATOM 184  C CZ  . PHE A 1 33  ? 151.497 174.469 100.432 1.00 11.31  ? 33  PHE A CZ  1 
ATOM 185  N N   . THR A 1 34  ? 147.648 172.826 103.567 1.00 14.94  ? 34  THR A N   1 
ATOM 186  C CA  . THR A 1 34  ? 148.393 171.976 104.478 1.00 16.02  ? 34  THR A CA  1 
ATOM 187  C C   . THR A 1 34  ? 149.548 171.351 103.717 1.00 14.41  ? 34  THR A C   1 
ATOM 188  O O   . THR A 1 34  ? 149.335 170.625 102.742 1.00 15.89  ? 34  THR A O   1 
ATOM 189  C CB  . THR A 1 34  ? 147.496 170.892 105.059 1.00 21.15  ? 34  THR A CB  1 
ATOM 190  O OG1 . THR A 1 34  ? 146.177 171.424 105.237 1.00 26.11  ? 34  THR A OG1 1 
ATOM 191  C CG2 . THR A 1 34  ? 148.043 170.418 106.385 1.00 26.80  ? 34  THR A CG2 1 
ATOM 192  N N   . TYR A 1 35  ? 150.759 171.627 104.169 1.00 13.39  ? 35  TYR A N   1 
ATOM 193  C CA  . TYR A 1 35  ? 151.963 171.114 103.543 1.00 12.53  ? 35  TYR A CA  1 
ATOM 194  C C   . TYR A 1 35  ? 152.417 169.879 104.301 1.00 13.46  ? 35  TYR A C   1 
ATOM 195  O O   . TYR A 1 35  ? 152.527 169.906 105.532 1.00 15.14  ? 35  TYR A O   1 
ATOM 196  C CB  . TYR A 1 35  ? 153.059 172.177 103.535 1.00 12.64  ? 35  TYR A CB  1 
ATOM 197  C CG  . TYR A 1 35  ? 154.345 171.740 102.880 1.00 12.45  ? 35  TYR A CG  1 
ATOM 198  C CD1 . TYR A 1 35  ? 154.340 171.149 101.627 1.00 12.30  ? 35  TYR A CD1 1 
ATOM 199  C CD2 . TYR A 1 35  ? 155.564 171.941 103.503 1.00 13.42  ? 35  TYR A CD2 1 
ATOM 200  C CE1 . TYR A 1 35  ? 155.515 170.755 101.019 1.00 13.50  ? 35  TYR A CE1 1 
ATOM 201  C CE2 . TYR A 1 35  ? 156.742 171.560 102.901 1.00 13.61  ? 35  TYR A CE2 1 
ATOM 202  C CZ  . TYR A 1 35  ? 156.712 170.962 101.662 1.00 14.29  ? 35  TYR A CZ  1 
ATOM 203  O OH  . TYR A 1 35  ? 157.886 170.572 101.059 1.00 17.00  ? 35  TYR A OH  1 
ATOM 204  N N   . GLY A 1 36  ? 152.656 168.793 103.564 1.00 13.32  ? 36  GLY A N   1 
ATOM 205  C CA  . GLY A 1 36  ? 153.123 167.571 104.189 1.00 14.17  ? 36  GLY A CA  1 
ATOM 206  C C   . GLY A 1 36  ? 154.461 167.737 104.871 1.00 13.92  ? 36  GLY A C   1 
ATOM 207  O O   . GLY A 1 36  ? 154.775 166.995 105.809 1.00 15.53  ? 36  GLY A O   1 
ATOM 208  N N   . GLY A 1 37  ? 155.247 168.712 104.439 1.00 13.32  ? 37  GLY A N   1 
ATOM 209  C CA  . GLY A 1 37  ? 156.570 168.926 104.968 1.00 14.52  ? 37  GLY A CA  1 
ATOM 210  C C   . GLY A 1 37  ? 157.693 168.465 104.070 1.00 15.20  ? 37  GLY A C   1 
ATOM 211  O O   . GLY A 1 37  ? 158.860 168.649 104.430 1.00 18.62  ? 37  GLY A O   1 
ATOM 212  N N   . CYS A 1 38  ? 157.386 167.884 102.912 1.00 15.21  ? 38  CYS A N   1 
ATOM 213  C CA  . CYS A 1 38  ? 158.427 167.342 102.054 1.00 17.77  ? 38  CYS A CA  1 
ATOM 214  C C   . CYS A 1 38  ? 157.973 167.376 100.603 1.00 16.63  ? 38  CYS A C   1 
ATOM 215  O O   . CYS A 1 38  ? 156.778 167.410 100.305 1.00 18.21  ? 38  CYS A O   1 
ATOM 216  C CB  . CYS A 1 38  ? 158.781 165.907 102.454 1.00 20.32  ? 38  CYS A CB  1 
ATOM 217  S SG  . CYS A 1 38  ? 157.542 164.700 101.940 1.00 24.25  ? 38  CYS A SG  1 
ATOM 218  N N   . ALA A 1 39  ? 158.958 167.358 99.706  1.00 20.63  ? 39  ALA A N   1 
ATOM 219  C CA  . ALA A 1 39  ? 158.740 167.193 98.268  1.00 20.96  ? 39  ALA A CA  1 
ATOM 220  C C   . ALA A 1 39  ? 157.726 168.197 97.721  1.00 20.17  ? 39  ALA A C   1 
ATOM 221  O O   . ALA A 1 39  ? 156.802 167.846 96.987  1.00 25.26  ? 39  ALA A O   1 
ATOM 222  C CB  . ALA A 1 39  ? 158.309 165.762 97.943  1.00 30.00  ? 39  ALA A CB  1 
ATOM 223  N N   . GLY A 1 40  ? 157.903 169.458 98.084  1.00 17.32  ? 40  GLY A N   1 
ATOM 224  C CA  . GLY A 1 40  ? 157.085 170.533 97.565  1.00 16.23  ? 40  GLY A CA  1 
ATOM 225  C C   . GLY A 1 40  ? 157.735 171.222 96.386  1.00 16.75  ? 40  GLY A C   1 
ATOM 226  O O   . GLY A 1 40  ? 158.522 170.626 95.642  1.00 24.02  ? 40  GLY A O   1 
ATOM 227  N N   . ASN A 1 41  ? 157.400 172.496 96.205  1.00 13.22  ? 41  ASN A N   1 
ATOM 228  C CA  . ASN A 1 41  ? 158.040 173.317 95.190  1.00 13.61  ? 41  ASN A CA  1 
ATOM 229  C C   . ASN A 1 41  ? 158.042 174.761 95.669  1.00 12.18  ? 41  ASN A C   1 
ATOM 230  O O   . ASN A 1 41  ? 157.636 175.066 96.795  1.00 13.13  ? 41  ASN A O   1 
ATOM 231  C CB  . ASN A 1 41  ? 157.351 173.162 93.833  1.00 13.93  ? 41  ASN A CB  1 
ATOM 232  C CG  . ASN A 1 41  ? 155.892 173.551 93.875  1.00 13.44  ? 41  ASN A CG  1 
ATOM 233  O OD1 . ASN A 1 41  ? 155.542 174.707 93.639  1.00 13.32  ? 41  ASN A OD1 1 
ATOM 234  N ND2 . ASN A 1 41  ? 155.028 172.587 94.178  1.00 14.67  ? 41  ASN A ND2 1 
ATOM 235  N N   . ALA A 1 42  ? 158.511 175.657 94.798  1.00 12.87  ? 42  ALA A N   1 
ATOM 236  C CA  . ALA A 1 42  ? 158.787 177.027 95.216  1.00 12.30  ? 42  ALA A CA  1 
ATOM 237  C C   . ALA A 1 42  ? 157.523 177.771 95.626  1.00 11.37  ? 42  ALA A C   1 
ATOM 238  O O   . ALA A 1 42  ? 157.594 178.707 96.430  1.00 12.20  ? 42  ALA A O   1 
ATOM 239  C CB  . ALA A 1 42  ? 159.506 177.781 94.098  1.00 15.04  ? 42  ALA A CB  1 
ATOM 240  N N   . ASN A 1 43  ? 156.367 177.376 95.095  1.00 10.70  ? 43  ASN A N   1 
ATOM 241  C CA  . ASN A 1 43  ? 155.109 178.062 95.389  1.00 10.03  ? 43  ASN A CA  1 
ATOM 242  C C   . ASN A 1 43  ? 154.567 177.581 96.736  1.00 9.88   ? 43  ASN A C   1 
ATOM 243  O O   . ASN A 1 43  ? 153.590 176.836 96.831  1.00 10.36  ? 43  ASN A O   1 
ATOM 244  C CB  . ASN A 1 43  ? 154.106 177.836 94.268  1.00 10.49  ? 43  ASN A CB  1 
ATOM 245  N N   . ARG A 1 44  ? 155.236 178.027 97.799  1.00 10.11  ? 44  ARG A N   1 
ATOM 246  C CA  . ARG A 1 44  ? 154.860 177.654 99.156  1.00 10.56  ? 44  ARG A CA  1 
ATOM 247  C C   . ARG A 1 44  ? 155.382 178.709 100.116 1.00 10.36  ? 44  ARG A C   1 
ATOM 248  O O   . ARG A 1 44  ? 156.557 179.082 100.048 1.00 11.89  ? 44  ARG A O   1 
ATOM 249  C CB  . ARG A 1 44  ? 155.417 176.278 99.522  1.00 11.55  ? 44  ARG A CB  1 
ATOM 250  C CG  . ARG A 1 44  ? 155.070 175.833 100.924 1.00 13.53  ? 44  ARG A CG  1 
ATOM 251  C CD  . ARG A 1 44  ? 155.653 174.469 101.215 1.00 17.87  ? 44  ARG A CD  1 
ATOM 252  N NE  . ARG A 1 44  ? 157.108 174.464 101.131 1.00 18.43  ? 44  ARG A NE  1 
ATOM 253  C CZ  . ARG A 1 44  ? 157.918 174.730 102.147 1.00 16.52  ? 44  ARG A CZ  1 
ATOM 254  N NH1 . ARG A 1 44  ? 157.448 175.023 103.349 1.00 19.40  ? 44  ARG A NH1 1 
ATOM 255  N NH2 . ARG A 1 44  ? 159.233 174.701 101.952 1.00 21.39  ? 44  ARG A NH2 1 
ATOM 256  N N   . PHE A 1 45  ? 154.518 179.174 101.014 1.00 10.07  ? 45  PHE A N   1 
ATOM 257  C CA  . PHE A 1 45  ? 154.850 180.266 101.915 1.00 10.87  ? 45  PHE A CA  1 
ATOM 258  C C   . PHE A 1 45  ? 154.511 179.890 103.349 1.00 10.95  ? 45  PHE A C   1 
ATOM 259  O O   . PHE A 1 45  ? 153.552 179.159 103.606 1.00 11.94  ? 45  PHE A O   1 
ATOM 260  C CB  . PHE A 1 45  ? 154.110 181.538 101.509 1.00 11.05  ? 45  PHE A CB  1 
ATOM 261  C CG  . PHE A 1 45  ? 154.406 181.976 100.109 1.00 10.75  ? 45  PHE A CG  1 
ATOM 262  C CD1 . PHE A 1 45  ? 153.663 181.491 99.047  1.00 10.92  ? 45  PHE A CD1 1 
ATOM 263  C CD2 . PHE A 1 45  ? 155.445 182.856 99.852  1.00 13.34  ? 45  PHE A CD2 1 
ATOM 264  C CE1 . PHE A 1 45  ? 153.938 181.890 97.756  1.00 11.69  ? 45  PHE A CE1 1 
ATOM 265  C CE2 . PHE A 1 45  ? 155.728 183.258 98.563  1.00 14.27  ? 45  PHE A CE2 1 
ATOM 266  C CZ  . PHE A 1 45  ? 154.975 182.774 97.513  1.00 13.05  ? 45  PHE A CZ  1 
ATOM 267  N N   . SER A 1 46  ? 155.318 180.384 104.286 1.00 11.62  ? 46  SER A N   1 
ATOM 268  C CA  . SER A 1 46  ? 155.054 180.145 105.696 1.00 13.13  ? 46  SER A CA  1 
ATOM 269  C C   . SER A 1 46  ? 154.094 181.163 106.295 1.00 12.93  ? 46  SER A C   1 
ATOM 270  O O   . SER A 1 46  ? 153.552 180.922 107.379 1.00 14.83  ? 46  SER A O   1 
ATOM 271  C CB  . SER A 1 46  ? 156.368 180.142 106.487 1.00 12.54  ? 46  SER A CB  1 
ATOM 272  O OG  . SER A 1 46  ? 157.016 181.399 106.414 1.00 18.27  ? 46  SER A OG  1 
ATOM 273  N N   . THR A 1 47  ? 153.863 182.282 105.616 1.00 11.95  ? 47  THR A N   1 
ATOM 274  C CA  . THR A 1 47  ? 152.975 183.323 106.113 1.00 12.41  ? 47  THR A CA  1 
ATOM 275  C C   . THR A 1 47  ? 152.134 183.839 104.954 1.00 11.57  ? 47  THR A C   1 
ATOM 276  O O   . THR A 1 47  ? 152.664 184.086 103.862 1.00 11.36  ? 47  THR A O   1 
ATOM 277  C CB  . THR A 1 47  ? 153.773 184.463 106.755 1.00 14.23  ? 47  THR A CB  1 
ATOM 278  O OG1 . THR A 1 47  ? 154.656 183.924 107.748 1.00 15.83  ? 47  THR A OG1 1 
ATOM 279  C CG2 . THR A 1 47  ? 152.843 185.477 107.407 1.00 15.62  ? 47  THR A CG2 1 
ATOM 280  N N   . ILE A 1 48  ? 150.827 183.993 105.190 1.00 11.34  ? 48  ILE A N   1 
ATOM 281  C CA  . ILE A 1 48  ? 149.929 184.460 104.135 1.00 10.62  ? 48  ILE A CA  1 
ATOM 282  C C   . ILE A 1 48  ? 150.353 185.838 103.654 1.00 11.27  ? 48  ILE A C   1 
ATOM 283  O O   . ILE A 1 48  ? 150.242 186.154 102.462 1.00 11.13  ? 48  ILE A O   1 
ATOM 284  C CB  . ILE A 1 48  ? 148.470 184.452 104.634 1.00 30.00  ? 48  ILE A CB  1 
ATOM 285  C CG1 . ILE A 1 48  ? 147.517 184.980 103.558 1.00 30.00  ? 48  ILE A CG1 1 
ATOM 286  C CG2 . ILE A 1 48  ? 148.334 185.249 105.921 1.00 30.00  ? 48  ILE A CG2 1 
ATOM 287  C CD1 . ILE A 1 48  ? 147.235 183.992 102.452 1.00 30.00  ? 48  ILE A CD1 1 
ATOM 288  N N   . GLU A 1 49  ? 150.859 186.672 104.563 1.00 12.03  ? 49  GLU A N   1 
ATOM 289  C CA  . GLU A 1 49  ? 151.321 187.997 104.174 1.00 13.38  ? 49  GLU A CA  1 
ATOM 290  C C   . GLU A 1 49  ? 152.526 187.913 103.248 1.00 13.14  ? 49  GLU A C   1 
ATOM 291  O O   . GLU A 1 49  ? 152.621 188.680 102.286 1.00 12.65  ? 49  GLU A O   1 
ATOM 292  C CB  . GLU A 1 49  ? 151.644 188.825 105.413 1.00 16.60  ? 49  GLU A CB  1 
ATOM 293  N N   . LYS A 1 50  ? 153.447 186.981 103.508 1.00 12.92  ? 50  LYS A N   1 
ATOM 294  C CA  . LYS A 1 50  ? 154.579 186.805 102.604 1.00 12.88  ? 50  LYS A CA  1 
ATOM 295  C C   . LYS A 1 50  ? 154.113 186.364 101.224 1.00 11.18  ? 50  LYS A C   1 
ATOM 296  O O   . LYS A 1 50  ? 154.611 186.858 100.204 1.00 12.02  ? 50  LYS A O   1 
ATOM 297  C CB  . LYS A 1 50  ? 155.570 185.798 103.185 1.00 14.92  ? 50  LYS A CB  1 
ATOM 298  N N   . CYS A 1 51  ? 153.143 185.442 101.176 1.00 10.56  ? 51  CYS A N   1 
ATOM 299  C CA  . CYS A 1 51  ? 152.593 185.009 99.891  1.00 10.37  ? 51  CYS A CA  1 
ATOM 300  C C   . CYS A 1 51  ? 151.985 186.179 99.132  1.00 10.10  ? 51  CYS A C   1 
ATOM 301  O O   . CYS A 1 51  ? 152.237 186.360 97.935  1.00 11.08  ? 51  CYS A O   1 
ATOM 302  C CB  . CYS A 1 51  ? 151.537 183.924 100.109 1.00 10.12  ? 51  CYS A CB  1 
ATOM 303  N N   . ARG A 1 52  ? 151.156 186.969 99.815  1.00 10.38  ? 52  ARG A N   1 
ATOM 304  C CA  . ARG A 1 52  ? 150.466 188.063 99.146  1.00 10.66  ? 52  ARG A CA  1 
ATOM 305  C C   . ARG A 1 52  ? 151.446 189.143 98.697  1.00 11.64  ? 52  ARG A C   1 
ATOM 306  O O   . ARG A 1 52  ? 151.274 189.728 97.616  1.00 12.67  ? 52  ARG A O   1 
ATOM 307  C CB  . ARG A 1 52  ? 149.388 188.634 100.065 1.00 11.51  ? 52  ARG A CB  1 
ATOM 308  N N   . ARG A 1 53  ? 152.485 189.407 99.491  1.00 11.74  ? 53  ARG A N   1 
ATOM 309  C CA  . ARG A 1 53  ? 153.501 190.358 99.057  1.00 13.30  ? 53  ARG A CA  1 
ATOM 310  C C   . ARG A 1 53  ? 154.272 189.832 97.852  1.00 13.07  ? 53  ARG A C   1 
ATOM 311  O O   . ARG A 1 53  ? 154.597 190.597 96.936  1.00 17.10  ? 53  ARG A O   1 
ATOM 312  C CB  . ARG A 1 53  ? 154.453 190.679 100.209 1.00 15.71  ? 53  ARG A CB  1 
ATOM 313  N N   . THR A 1 54  ? 154.569 188.532 97.828  1.00 11.18  ? 54  THR A N   1 
ATOM 314  C CA  . THR A 1 54  ? 155.372 187.984 96.741  1.00 11.09  ? 54  THR A CA  1 
ATOM 315  C C   . THR A 1 54  ? 154.586 187.914 95.437  1.00 11.08  ? 54  THR A C   1 
ATOM 316  O O   . THR A 1 54  ? 155.087 188.312 94.380  1.00 13.80  ? 54  THR A O   1 
ATOM 317  C CB  . THR A 1 54  ? 155.897 186.600 97.120  1.00 11.40  ? 54  THR A CB  1 
ATOM 318  N N   . CYS A 1 55  ? 153.345 187.428 95.489  1.00 10.81  ? 55  CYS A N   1 
ATOM 319  C CA  . CYS A 1 55  ? 152.651 186.982 94.287  1.00 11.26  ? 55  CYS A CA  1 
ATOM 320  C C   . CYS A 1 55  ? 151.451 187.826 93.885  1.00 11.74  ? 55  CYS A C   1 
ATOM 321  O O   . CYS A 1 55  ? 151.177 187.936 92.688  1.00 13.63  ? 55  CYS A O   1 
ATOM 322  C CB  . CYS A 1 55  ? 152.179 185.535 94.464  1.00 11.85  ? 55  CYS A CB  1 
ATOM 323  N N   . VAL A 1 56  ? 150.725 188.415 94.842  1.00 12.06  ? 56  VAL A N   1 
ATOM 324  C CA  . VAL A 1 56  ? 149.486 189.103 94.497  1.00 13.06  ? 56  VAL A CA  1 
ATOM 325  C C   . VAL A 1 56  ? 149.622 190.617 94.591  1.00 14.48  ? 56  VAL A C   1 
ATOM 326  O O   . VAL A 1 56  ? 148.781 191.339 94.049  1.00 16.45  ? 56  VAL A O   1 
ATOM 327  C CB  . VAL A 1 56  ? 148.323 188.611 95.383  1.00 13.03  ? 56  VAL A CB  1 
ATOM 328  N N   . GLU B 2 4   ? 128.493 131.803 178.257 1.00 106.15 ? 4   GLU H N   1 
ATOM 329  C CA  . GLU B 2 4   ? 129.333 132.912 178.695 1.00 106.15 ? 4   GLU H CA  1 
ATOM 330  C C   . GLU B 2 4   ? 130.713 132.427 179.119 1.00 106.15 ? 4   GLU H C   1 
ATOM 331  O O   . GLU B 2 4   ? 130.835 131.501 179.919 1.00 106.15 ? 4   GLU H O   1 
ATOM 332  C CB  . GLU B 2 4   ? 128.669 133.664 179.847 1.00 106.15 ? 4   GLU H CB  1 
ATOM 333  C CG  . GLU B 2 4   ? 129.493 134.822 180.382 1.00 106.15 ? 4   GLU H CG  1 
ATOM 334  C CD  . GLU B 2 4   ? 128.860 135.462 181.597 1.00 106.15 ? 4   GLU H CD  1 
ATOM 335  O OE1 . GLU B 2 4   ? 127.746 135.038 181.970 1.00 106.15 ? 4   GLU H OE1 1 
ATOM 336  O OE2 . GLU B 2 4   ? 129.473 136.381 182.179 1.00 106.15 ? 4   GLU H OE2 1 
ATOM 337  N N   . VAL B 2 5   ? 131.750 133.064 178.586 1.00 98.23  ? 5   VAL H N   1 
ATOM 338  C CA  . VAL B 2 5   ? 133.131 132.688 178.865 1.00 98.23  ? 5   VAL H CA  1 
ATOM 339  C C   . VAL B 2 5   ? 133.581 133.373 180.146 1.00 98.23  ? 5   VAL H C   1 
ATOM 340  O O   . VAL B 2 5   ? 133.457 134.595 180.281 1.00 98.23  ? 5   VAL H O   1 
ATOM 341  C CB  . VAL B 2 5   ? 134.047 133.063 177.689 1.00 98.23  ? 5   VAL H CB  1 
ATOM 342  C CG1 . VAL B 2 5   ? 135.501 132.783 178.037 1.00 98.23  ? 5   VAL H CG1 1 
ATOM 343  C CG2 . VAL B 2 5   ? 133.630 132.316 176.431 1.00 98.23  ? 5   VAL H CG2 1 
ATOM 344  N N   . GLN B 2 6   ? 134.105 132.592 181.089 1.00 95.47  ? 6   GLN H N   1 
ATOM 345  C CA  . GLN B 2 6   ? 134.602 133.165 182.332 1.00 95.47  ? 6   GLN H CA  1 
ATOM 346  C C   . GLN B 2 6   ? 135.542 132.183 183.017 1.00 95.47  ? 6   GLN H C   1 
ATOM 347  O O   . GLN B 2 6   ? 135.439 130.968 182.833 1.00 95.47  ? 6   GLN H O   1 
ATOM 348  C CB  . GLN B 2 6   ? 133.453 133.545 183.275 1.00 95.47  ? 6   GLN H CB  1 
ATOM 349  C CG  . GLN B 2 6   ? 133.878 134.309 184.527 1.00 95.47  ? 6   GLN H CG  1 
ATOM 350  C CD  . GLN B 2 6   ? 134.676 135.565 184.212 1.00 95.47  ? 6   GLN H CD  1 
ATOM 351  O OE1 . GLN B 2 6   ? 135.893 135.515 184.033 1.00 95.47  ? 6   GLN H OE1 1 
ATOM 352  N NE2 . GLN B 2 6   ? 133.990 136.701 184.148 1.00 95.47  ? 6   GLN H NE2 1 
ATOM 353  N N   . LEU B 2 7   ? 136.469 132.731 183.795 1.00 86.44  ? 7   LEU H N   1 
ATOM 354  C CA  . LEU B 2 7   ? 137.338 131.959 184.669 1.00 86.44  ? 7   LEU H CA  1 
ATOM 355  C C   . LEU B 2 7   ? 137.103 132.404 186.105 1.00 86.44  ? 7   LEU H C   1 
ATOM 356  O O   . LEU B 2 7   ? 137.094 133.605 186.392 1.00 86.44  ? 7   LEU H O   1 
ATOM 357  C CB  . LEU B 2 7   ? 138.806 132.135 184.281 1.00 86.44  ? 7   LEU H CB  1 
ATOM 358  C CG  . LEU B 2 7   ? 139.140 131.641 182.873 1.00 86.44  ? 7   LEU H CG  1 
ATOM 359  C CD1 . LEU B 2 7   ? 140.528 132.064 182.450 1.00 86.44  ? 7   LEU H CD1 1 
ATOM 360  C CD2 . LEU B 2 7   ? 139.006 130.131 182.799 1.00 86.44  ? 7   LEU H CD2 1 
ATOM 361  N N   . VAL B 2 8   ? 136.910 131.442 187.002 1.00 91.42  ? 8   VAL H N   1 
ATOM 362  C CA  . VAL B 2 8   ? 136.592 131.716 188.400 1.00 91.42  ? 8   VAL H CA  1 
ATOM 363  C C   . VAL B 2 8   ? 137.668 131.066 189.253 1.00 91.42  ? 8   VAL H C   1 
ATOM 364  O O   . VAL B 2 8   ? 137.776 129.834 189.295 1.00 91.42  ? 8   VAL H O   1 
ATOM 365  C CB  . VAL B 2 8   ? 135.201 131.202 188.786 1.00 91.42  ? 8   VAL H CB  1 
ATOM 366  C CG1 . VAL B 2 8   ? 134.957 131.427 190.260 1.00 91.42  ? 8   VAL H CG1 1 
ATOM 367  C CG2 . VAL B 2 8   ? 134.136 131.897 187.960 1.00 91.42  ? 8   VAL H CG2 1 
ATOM 368  N N   . GLU B 2 9   ? 138.463 131.884 189.930 1.00 89.87  ? 9   GLU H N   1 
ATOM 369  C CA  . GLU B 2 9   ? 139.548 131.414 190.775 1.00 89.87  ? 9   GLU H CA  1 
ATOM 370  C C   . GLU B 2 9   ? 139.086 131.368 192.227 1.00 89.87  ? 9   GLU H C   1 
ATOM 371  O O   . GLU B 2 9   ? 138.305 132.215 192.668 1.00 89.87  ? 9   GLU H O   1 
ATOM 372  C CB  . GLU B 2 9   ? 140.772 132.320 190.643 1.00 89.87  ? 9   GLU H CB  1 
ATOM 373  C CG  . GLU B 2 9   ? 141.374 132.368 189.249 1.00 89.87  ? 9   GLU H CG  1 
ATOM 374  C CD  . GLU B 2 9   ? 140.651 133.318 188.301 1.00 89.87  ? 9   GLU H CD  1 
ATOM 375  O OE1 . GLU B 2 9   ? 139.596 133.870 188.667 1.00 89.87  ? 9   GLU H OE1 1 
ATOM 376  O OE2 . GLU B 2 9   ? 141.149 133.537 187.179 1.00 89.87  ? 9   GLU H OE2 1 
ATOM 377  N N   . SER B 2 10  ? 139.567 130.371 192.963 1.00 98.01  ? 10  SER H N   1 
ATOM 378  C CA  . SER B 2 10  ? 139.183 130.203 194.357 1.00 98.01  ? 10  SER H CA  1 
ATOM 379  C C   . SER B 2 10  ? 140.237 129.362 195.058 1.00 98.01  ? 10  SER H C   1 
ATOM 380  O O   . SER B 2 10  ? 141.139 128.806 194.430 1.00 98.01  ? 10  SER H O   1 
ATOM 381  C CB  . SER B 2 10  ? 137.796 129.565 194.484 1.00 98.01  ? 10  SER H CB  1 
ATOM 382  O OG  . SER B 2 10  ? 137.767 128.275 193.904 1.00 98.01  ? 10  SER H OG  1 
ATOM 383  N N   . GLY B 2 11  ? 140.114 129.279 196.377 1.00 104.51 ? 11  GLY H N   1 
ATOM 384  C CA  . GLY B 2 11  ? 141.041 128.516 197.178 1.00 104.51 ? 11  GLY H CA  1 
ATOM 385  C C   . GLY B 2 11  ? 142.179 129.305 197.778 1.00 104.51 ? 11  GLY H C   1 
ATOM 386  O O   . GLY B 2 11  ? 143.130 128.698 198.281 1.00 104.51 ? 11  GLY H O   1 
ATOM 387  N N   . GLY B 2 12  ? 142.120 130.630 197.737 1.00 106.75 ? 12  GLY H N   1 
ATOM 388  C CA  . GLY B 2 12  ? 143.157 131.460 198.308 1.00 106.75 ? 12  GLY H CA  1 
ATOM 389  C C   . GLY B 2 12  ? 142.934 131.683 199.789 1.00 106.75 ? 12  GLY H C   1 
ATOM 390  O O   . GLY B 2 12  ? 142.196 130.956 200.454 1.00 106.75 ? 12  GLY H O   1 
ATOM 391  N N   . GLY B 2 13  ? 143.576 132.722 200.307 1.00 112.86 ? 13  GLY H N   1 
ATOM 392  C CA  . GLY B 2 13  ? 143.514 133.003 201.721 1.00 112.86 ? 13  GLY H CA  1 
ATOM 393  C C   . GLY B 2 13  ? 144.880 132.993 202.372 1.00 112.86 ? 13  GLY H C   1 
ATOM 394  O O   . GLY B 2 13  ? 145.922 133.111 201.712 1.00 112.86 ? 13  GLY H O   1 
ATOM 395  N N   . LEU B 2 14  ? 144.869 132.876 203.693 1.00 118.25 ? 14  LEU H N   1 
ATOM 396  C CA  . LEU B 2 14  ? 146.072 132.968 204.501 1.00 118.25 ? 14  LEU H CA  1 
ATOM 397  C C   . LEU B 2 14  ? 146.613 131.571 204.773 1.00 118.25 ? 14  LEU H C   1 
ATOM 398  O O   . LEU B 2 14  ? 145.882 130.693 205.238 1.00 118.25 ? 14  LEU H O   1 
ATOM 399  C CB  . LEU B 2 14  ? 145.774 133.697 205.815 1.00 118.25 ? 14  LEU H CB  1 
ATOM 400  C CG  . LEU B 2 14  ? 146.901 133.781 206.844 1.00 118.25 ? 14  LEU H CG  1 
ATOM 401  C CD1 . LEU B 2 14  ? 148.069 134.602 206.320 1.00 118.25 ? 14  LEU H CD1 1 
ATOM 402  C CD2 . LEU B 2 14  ? 146.381 134.347 208.156 1.00 118.25 ? 14  LEU H CD2 1 
ATOM 403  N N   . VAL B 2 15  ? 147.891 131.365 204.460 1.00 117.63 ? 15  VAL H N   1 
ATOM 404  C CA  . VAL B 2 15  ? 148.594 130.139 204.802 1.00 117.63 ? 15  VAL H CA  1 
ATOM 405  C C   . VAL B 2 15  ? 149.934 130.516 205.411 1.00 117.63 ? 15  VAL H C   1 
ATOM 406  O O   . VAL B 2 15  ? 150.410 131.644 205.294 1.00 117.63 ? 15  VAL H O   1 
ATOM 407  C CB  . VAL B 2 15  ? 148.795 129.205 203.586 1.00 117.63 ? 15  VAL H CB  1 
ATOM 408  C CG1 . VAL B 2 15  ? 147.454 128.767 203.021 1.00 117.63 ? 15  VAL H CG1 1 
ATOM 409  C CG2 . VAL B 2 15  ? 149.634 129.892 202.524 1.00 117.63 ? 15  VAL H CG2 1 
ATOM 410  N N   . GLN B 2 16  ? 150.537 129.543 206.070 1.00 119.00 ? 16  GLN H N   1 
ATOM 411  C CA  . GLN B 2 16  ? 151.822 129.701 206.729 1.00 119.00 ? 16  GLN H CA  1 
ATOM 412  C C   . GLN B 2 16  ? 152.942 129.607 205.707 1.00 119.00 ? 16  GLN H C   1 
ATOM 413  O O   . GLN B 2 16  ? 152.722 129.218 204.562 1.00 119.00 ? 16  GLN H O   1 
ATOM 414  C CB  . GLN B 2 16  ? 151.976 128.621 207.797 1.00 119.00 ? 16  GLN H CB  1 
ATOM 415  C CG  . GLN B 2 16  ? 150.840 128.575 208.800 1.00 119.00 ? 16  GLN H CG  1 
ATOM 416  C CD  . GLN B 2 16  ? 150.891 129.722 209.781 1.00 119.00 ? 16  GLN H CD  1 
ATOM 417  O OE1 . GLN B 2 16  ? 151.948 130.041 210.322 1.00 119.00 ? 16  GLN H OE1 1 
ATOM 418  N NE2 . GLN B 2 16  ? 149.748 130.354 210.015 1.00 119.00 ? 16  GLN H NE2 1 
ATOM 419  N N   . PRO B 2 17  ? 154.165 129.992 206.079 1.00 120.80 ? 17  PRO H N   1 
ATOM 420  C CA  . PRO B 2 17  ? 155.302 129.755 205.178 1.00 120.80 ? 17  PRO H CA  1 
ATOM 421  C C   . PRO B 2 17  ? 155.724 128.291 205.129 1.00 120.80 ? 17  PRO H C   1 
ATOM 422  O O   . PRO B 2 17  ? 156.892 127.963 205.360 1.00 120.80 ? 17  PRO H O   1 
ATOM 423  C CB  . PRO B 2 17  ? 156.405 130.647 205.761 1.00 120.80 ? 17  PRO H CB  1 
ATOM 424  C CG  . PRO B 2 17  ? 156.027 130.844 207.181 1.00 120.80 ? 17  PRO H CG  1 
ATOM 425  C CD  . PRO B 2 17  ? 154.533 130.857 207.213 1.00 120.80 ? 17  PRO H CD  1 
ATOM 426  N N   . GLY B 2 18  ? 154.773 127.406 204.833 1.00 119.45 ? 18  GLY H N   1 
ATOM 427  C CA  . GLY B 2 18  ? 155.028 125.991 204.650 1.00 119.45 ? 18  GLY H CA  1 
ATOM 428  C C   . GLY B 2 18  ? 154.283 125.452 203.447 1.00 119.45 ? 18  GLY H C   1 
ATOM 429  O O   . GLY B 2 18  ? 154.433 124.287 203.074 1.00 119.45 ? 18  GLY H O   1 
ATOM 430  N N   . GLY B 2 19  ? 153.467 126.305 202.836 1.00 118.76 ? 19  GLY H N   1 
ATOM 431  C CA  . GLY B 2 19  ? 152.825 125.949 201.584 1.00 118.76 ? 19  GLY H CA  1 
ATOM 432  C C   . GLY B 2 19  ? 151.689 124.962 201.756 1.00 118.76 ? 19  GLY H C   1 
ATOM 433  O O   . GLY B 2 19  ? 150.883 125.053 202.686 1.00 118.76 ? 19  GLY H O   1 
ATOM 434  N N   . SER B 2 20  ? 151.625 124.004 200.829 1.00 115.45 ? 20  SER H N   1 
ATOM 435  C CA  . SER B 2 20  ? 150.517 123.051 200.728 1.00 115.45 ? 20  SER H CA  1 
ATOM 436  C C   . SER B 2 20  ? 149.182 123.761 200.511 1.00 115.45 ? 20  SER H C   1 
ATOM 437  O O   . SER B 2 20  ? 148.162 123.391 201.092 1.00 115.45 ? 20  SER H O   1 
ATOM 438  C CB  . SER B 2 20  ? 150.455 122.133 201.952 1.00 115.45 ? 20  SER H CB  1 
ATOM 439  O OG  . SER B 2 20  ? 151.671 121.423 202.112 1.00 115.45 ? 20  SER H OG  1 
ATOM 440  N N   . LEU B 2 21  ? 149.179 124.781 199.655 1.00 107.41 ? 21  LEU H N   1 
ATOM 441  C CA  . LEU B 2 21  ? 147.966 125.515 199.312 1.00 107.41 ? 21  LEU H CA  1 
ATOM 442  C C   . LEU B 2 21  ? 147.569 125.202 197.876 1.00 107.41 ? 21  LEU H C   1 
ATOM 443  O O   . LEU B 2 21  ? 148.403 125.271 196.971 1.00 107.41 ? 21  LEU H O   1 
ATOM 444  C CB  . LEU B 2 21  ? 148.173 127.021 199.491 1.00 107.41 ? 21  LEU H CB  1 
ATOM 445  C CG  . LEU B 2 21  ? 146.972 127.915 199.193 1.00 107.41 ? 21  LEU H CG  1 
ATOM 446  C CD1 . LEU B 2 21  ? 145.774 127.490 200.024 1.00 107.41 ? 21  LEU H CD1 1 
ATOM 447  C CD2 . LEU B 2 21  ? 147.323 129.359 199.460 1.00 107.41 ? 21  LEU H CD2 1 
ATOM 448  N N   . ARG B 2 22  ? 146.298 124.869 197.662 1.00 101.21 ? 22  ARG H N   1 
ATOM 449  C CA  . ARG B 2 22  ? 145.805 124.519 196.335 1.00 101.21 ? 22  ARG H CA  1 
ATOM 450  C C   . ARG B 2 22  ? 144.772 125.531 195.867 1.00 101.21 ? 22  ARG H C   1 
ATOM 451  O O   . ARG B 2 22  ? 143.751 125.737 196.531 1.00 101.21 ? 22  ARG H O   1 
ATOM 452  C CB  . ARG B 2 22  ? 145.201 123.117 196.312 1.00 101.21 ? 22  ARG H CB  1 
ATOM 453  C CG  . ARG B 2 22  ? 144.422 122.829 195.038 1.00 101.21 ? 22  ARG H CG  1 
ATOM 454  C CD  . ARG B 2 22  ? 143.986 121.388 194.955 1.00 101.21 ? 22  ARG H CD  1 
ATOM 455  N NE  . ARG B 2 22  ? 145.124 120.484 195.032 1.00 101.21 ? 22  ARG H NE  1 
ATOM 456  C CZ  . ARG B 2 22  ? 145.073 119.193 194.735 1.00 101.21 ? 22  ARG H CZ  1 
ATOM 457  N NH1 . ARG B 2 22  ? 143.954 118.624 194.316 1.00 101.21 ? 22  ARG H NH1 1 
ATOM 458  N NH2 . ARG B 2 22  ? 146.172 118.455 194.859 1.00 101.21 ? 22  ARG H NH2 1 
ATOM 459  N N   . LEU B 2 23  ? 145.026 126.128 194.708 1.00 92.75  ? 23  LEU H N   1 
ATOM 460  C CA  . LEU B 2 23  ? 144.114 127.053 194.057 1.00 92.75  ? 23  LEU H CA  1 
ATOM 461  C C   . LEU B 2 23  ? 143.393 126.359 192.911 1.00 92.75  ? 23  LEU H C   1 
ATOM 462  O O   . LEU B 2 23  ? 143.990 125.569 192.175 1.00 92.75  ? 23  LEU H O   1 
ATOM 463  C CB  . LEU B 2 23  ? 144.869 128.269 193.524 1.00 92.75  ? 23  LEU H CB  1 
ATOM 464  C CG  . LEU B 2 23  ? 145.770 128.985 194.523 1.00 92.75  ? 23  LEU H CG  1 
ATOM 465  C CD1 . LEU B 2 23  ? 146.587 130.054 193.826 1.00 92.75  ? 23  LEU H CD1 1 
ATOM 466  C CD2 . LEU B 2 23  ? 144.918 129.590 195.614 1.00 92.75  ? 23  LEU H CD2 1 
ATOM 467  N N   . SER B 2 24  ? 142.117 126.678 192.754 1.00 90.44  ? 24  SER H N   1 
ATOM 468  C CA  . SER B 2 24  ? 141.261 126.059 191.755 1.00 90.44  ? 24  SER H CA  1 
ATOM 469  C C   . SER B 2 24  ? 140.700 127.119 190.819 1.00 90.44  ? 24  SER H C   1 
ATOM 470  O O   . SER B 2 24  ? 140.097 128.097 191.272 1.00 90.44  ? 24  SER H O   1 
ATOM 471  C CB  . SER B 2 24  ? 140.120 125.293 192.420 1.00 90.44  ? 24  SER H CB  1 
ATOM 472  O OG  . SER B 2 24  ? 139.099 124.985 191.492 1.00 90.44  ? 24  SER H OG  1 
ATOM 473  N N   . CYS B 2 25  ? 140.882 126.910 189.519 1.00 92.54  ? 25  CYS H N   1 
ATOM 474  C CA  . CYS B 2 25  ? 140.360 127.781 188.474 1.00 92.54  ? 25  CYS H CA  1 
ATOM 475  C C   . CYS B 2 25  ? 139.323 126.996 187.686 1.00 92.54  ? 25  CYS H C   1 
ATOM 476  O O   . CYS B 2 25  ? 139.673 126.088 186.927 1.00 92.54  ? 25  CYS H O   1 
ATOM 477  C CB  . CYS B 2 25  ? 141.477 128.266 187.557 1.00 92.54  ? 25  CYS H CB  1 
ATOM 478  S SG  . CYS B 2 25  ? 140.931 128.951 185.975 1.00 92.54  ? 25  CYS H SG  1 
ATOM 479  N N   . ALA B 2 26  ? 138.055 127.336 187.873 1.00 96.82  ? 26  ALA H N   1 
ATOM 480  C CA  . ALA B 2 26  ? 136.982 126.754 187.087 1.00 96.82  ? 26  ALA H CA  1 
ATOM 481  C C   . ALA B 2 26  ? 136.777 127.578 185.829 1.00 96.82  ? 26  ALA H C   1 
ATOM 482  O O   . ALA B 2 26  ? 136.960 128.796 185.827 1.00 96.82  ? 26  ALA H O   1 
ATOM 483  C CB  . ALA B 2 26  ? 135.686 126.689 187.893 1.00 96.82  ? 26  ALA H CB  1 
ATOM 484  N N   . ALA B 2 27  ? 136.408 126.899 184.748 1.00 96.47  ? 27  ALA H N   1 
ATOM 485  C CA  . ALA B 2 27  ? 136.202 127.533 183.458 1.00 96.47  ? 27  ALA H CA  1 
ATOM 486  C C   . ALA B 2 27  ? 134.751 127.382 183.027 1.00 96.47  ? 27  ALA H C   1 
ATOM 487  O O   . ALA B 2 27  ? 134.089 126.391 183.348 1.00 96.47  ? 27  ALA H O   1 
ATOM 488  C CB  . ALA B 2 27  ? 137.128 126.927 182.401 1.00 96.47  ? 27  ALA H CB  1 
ATOM 489  N N   . SER B 2 28  ? 134.255 128.380 182.301 1.00 99.09  ? 28  SER H N   1 
ATOM 490  C CA  . SER B 2 28  ? 132.933 128.311 181.704 1.00 99.09  ? 28  SER H CA  1 
ATOM 491  C C   . SER B 2 28  ? 132.986 128.952 180.327 1.00 99.09  ? 28  SER H C   1 
ATOM 492  O O   . SER B 2 28  ? 133.768 129.876 180.087 1.00 99.09  ? 28  SER H O   1 
ATOM 493  C CB  . SER B 2 28  ? 131.878 128.996 182.579 1.00 99.09  ? 28  SER H CB  1 
ATOM 494  O OG  . SER B 2 28  ? 130.579 128.801 182.051 1.00 99.09  ? 28  SER H OG  1 
ATOM 495  N N   . GLY B 2 29  ? 132.148 128.451 179.423 1.00 97.57  ? 29  GLY H N   1 
ATOM 496  C CA  . GLY B 2 29  ? 132.139 128.924 178.051 1.00 97.57  ? 29  GLY H CA  1 
ATOM 497  C C   . GLY B 2 29  ? 133.175 128.235 177.187 1.00 97.57  ? 29  GLY H C   1 
ATOM 498  O O   . GLY B 2 29  ? 132.827 127.495 176.262 1.00 97.57  ? 29  GLY H O   1 
ATOM 499  N N   . PHE B 2 30  ? 134.452 128.461 177.485 1.00 90.69  ? 30  PHE H N   1 
ATOM 500  C CA  . PHE B 2 30  ? 135.553 127.789 176.806 1.00 90.69  ? 30  PHE H CA  1 
ATOM 501  C C   . PHE B 2 30  ? 136.044 126.654 177.691 1.00 90.69  ? 30  PHE H C   1 
ATOM 502  O O   . PHE B 2 30  ? 136.395 126.878 178.853 1.00 90.69  ? 30  PHE H O   1 
ATOM 503  C CB  . PHE B 2 30  ? 136.705 128.749 176.510 1.00 90.69  ? 30  PHE H CB  1 
ATOM 504  C CG  . PHE B 2 30  ? 136.398 129.781 175.466 1.00 90.69  ? 30  PHE H CG  1 
ATOM 505  C CD1 . PHE B 2 30  ? 135.379 129.585 174.553 1.00 90.69  ? 30  PHE H CD1 1 
ATOM 506  C CD2 . PHE B 2 30  ? 137.144 130.947 175.392 1.00 90.69  ? 30  PHE H CD2 1 
ATOM 507  C CE1 . PHE B 2 30  ? 135.104 130.533 173.593 1.00 90.69  ? 30  PHE H CE1 1 
ATOM 508  C CE2 . PHE B 2 30  ? 136.875 131.896 174.436 1.00 90.69  ? 30  PHE H CE2 1 
ATOM 509  C CZ  . PHE B 2 30  ? 135.852 131.690 173.533 1.00 90.69  ? 30  PHE H CZ  1 
ATOM 510  N N   . ASN B 2 31  ? 136.069 125.444 177.149 1.00 93.97  ? 31  ASN H N   1 
ATOM 511  C CA  . ASN B 2 31  ? 136.512 124.300 177.924 1.00 93.97  ? 31  ASN H CA  1 
ATOM 512  C C   . ASN B 2 31  ? 138.030 124.292 178.043 1.00 93.97  ? 31  ASN H C   1 
ATOM 513  O O   . ASN B 2 31  ? 138.747 124.736 177.143 1.00 93.97  ? 31  ASN H O   1 
ATOM 514  C CB  . ASN B 2 31  ? 136.029 123.001 177.286 1.00 93.97  ? 31  ASN H CB  1 
ATOM 515  C CG  . ASN B 2 31  ? 135.998 121.854 178.265 1.00 93.97  ? 31  ASN H CG  1 
ATOM 516  O OD1 . ASN B 2 31  ? 137.030 121.260 178.574 1.00 93.97  ? 31  ASN H OD1 1 
ATOM 517  N ND2 . ASN B 2 31  ? 134.809 121.530 178.759 1.00 93.97  ? 31  ASN H ND2 1 
ATOM 518  N N   . VAL B 2 32  ? 138.520 123.772 179.171 1.00 94.32  ? 32  VAL H N   1 
ATOM 519  C CA  . VAL B 2 32  ? 139.957 123.697 179.398 1.00 94.32  ? 32  VAL H CA  1 
ATOM 520  C C   . VAL B 2 32  ? 140.631 122.805 178.369 1.00 94.32  ? 32  VAL H C   1 
ATOM 521  O O   . VAL B 2 32  ? 141.855 122.854 178.212 1.00 94.32  ? 32  VAL H O   1 
ATOM 522  C CB  . VAL B 2 32  ? 140.243 123.203 180.831 1.00 94.32  ? 32  VAL H CB  1 
ATOM 523  C CG1 . VAL B 2 32  ? 139.511 124.070 181.842 1.00 94.32  ? 32  VAL H CG1 1 
ATOM 524  C CG2 . VAL B 2 32  ? 139.846 121.739 180.980 1.00 94.32  ? 32  VAL H CG2 1 
ATOM 525  N N   . VAL B 2 33  ? 139.858 121.973 177.671 1.00 94.72  ? 33  VAL H N   1 
ATOM 526  C CA  . VAL B 2 33  ? 140.413 121.141 176.609 1.00 94.72  ? 33  VAL H CA  1 
ATOM 527  C C   . VAL B 2 33  ? 140.794 121.991 175.405 1.00 94.72  ? 33  VAL H C   1 
ATOM 528  O O   . VAL B 2 33  ? 141.829 121.765 174.766 1.00 94.72  ? 33  VAL H O   1 
ATOM 529  C CB  . VAL B 2 33  ? 139.408 120.036 176.239 1.00 94.72  ? 33  VAL H CB  1 
ATOM 530  C CG1 . VAL B 2 33  ? 139.761 119.401 174.903 1.00 94.72  ? 33  VAL H CG1 1 
ATOM 531  C CG2 . VAL B 2 33  ? 139.361 118.991 177.340 1.00 94.72  ? 33  VAL H CG2 1 
ATOM 532  N N   . ASP B 2 34  ? 139.971 122.988 175.083 1.00 89.84  ? 34  ASP H N   1 
ATOM 533  C CA  . ASP B 2 34  ? 140.187 123.800 173.893 1.00 89.84  ? 34  ASP H CA  1 
ATOM 534  C C   . ASP B 2 34  ? 141.274 124.850 174.083 1.00 89.84  ? 34  ASP H C   1 
ATOM 535  O O   . ASP B 2 34  ? 141.883 125.276 173.097 1.00 89.84  ? 34  ASP H O   1 
ATOM 536  C CB  . ASP B 2 34  ? 138.879 124.470 173.482 1.00 89.84  ? 34  ASP H CB  1 
ATOM 537  C CG  . ASP B 2 34  ? 137.703 123.521 173.537 1.00 89.84  ? 34  ASP H CG  1 
ATOM 538  O OD1 . ASP B 2 34  ? 137.874 122.338 173.181 1.00 89.84  ? 34  ASP H OD1 1 
ATOM 539  O OD2 . ASP B 2 34  ? 136.610 123.949 173.955 1.00 89.84  ? 34  ASP H OD2 1 
ATOM 540  N N   . PHE B 2 35  ? 141.524 125.291 175.313 1.00 78.78  ? 35  PHE H N   1 
ATOM 541  C CA  . PHE B 2 35  ? 142.502 126.337 175.581 1.00 78.78  ? 35  PHE H CA  1 
ATOM 542  C C   . PHE B 2 35  ? 143.492 125.886 176.642 1.00 78.78  ? 35  PHE H C   1 
ATOM 543  O O   . PHE B 2 35  ? 143.113 125.243 177.624 1.00 78.78  ? 35  PHE H O   1 
ATOM 544  C CB  . PHE B 2 35  ? 141.822 127.627 176.049 1.00 78.78  ? 35  PHE H CB  1 
ATOM 545  C CG  . PHE B 2 35  ? 140.964 128.267 175.010 1.00 78.78  ? 35  PHE H CG  1 
ATOM 546  C CD1 . PHE B 2 35  ? 139.697 127.780 174.741 1.00 78.78  ? 35  PHE H CD1 1 
ATOM 547  C CD2 . PHE B 2 35  ? 141.419 129.363 174.308 1.00 78.78  ? 35  PHE H CD2 1 
ATOM 548  C CE1 . PHE B 2 35  ? 138.908 128.364 173.784 1.00 78.78  ? 35  PHE H CE1 1 
ATOM 549  C CE2 . PHE B 2 35  ? 140.637 129.955 173.352 1.00 78.78  ? 35  PHE H CE2 1 
ATOM 550  C CZ  . PHE B 2 35  ? 139.376 129.457 173.089 1.00 78.78  ? 35  PHE H CZ  1 
ATOM 551  N N   . SER B 2 36  ? 144.757 126.235 176.449 1.00 67.75  ? 36  SER H N   1 
ATOM 552  C CA  . SER B 2 36  ? 145.722 126.077 177.521 1.00 67.75  ? 36  SER H CA  1 
ATOM 553  C C   . SER B 2 36  ? 145.467 127.121 178.600 1.00 67.75  ? 36  SER H C   1 
ATOM 554  O O   . SER B 2 36  ? 145.005 128.234 178.327 1.00 67.75  ? 36  SER H O   1 
ATOM 555  C CB  . SER B 2 36  ? 147.143 126.213 176.998 1.00 67.75  ? 36  SER H CB  1 
ATOM 556  O OG  . SER B 2 36  ? 147.441 127.565 176.734 1.00 67.75  ? 36  SER H OG  1 
ATOM 557  N N   . LEU B 2 37  ? 145.775 126.755 179.840 1.00 67.74  ? 37  LEU H N   1 
ATOM 558  C CA  . LEU B 2 37  ? 145.475 127.591 180.990 1.00 67.74  ? 37  LEU H CA  1 
ATOM 559  C C   . LEU B 2 37  ? 146.763 128.023 181.666 1.00 67.74  ? 37  LEU H C   1 
ATOM 560  O O   . LEU B 2 37  ? 147.666 127.208 181.875 1.00 67.74  ? 37  LEU H O   1 
ATOM 561  C CB  . LEU B 2 37  ? 144.575 126.863 181.980 1.00 67.74  ? 37  LEU H CB  1 
ATOM 562  C CG  . LEU B 2 37  ? 143.131 126.736 181.521 1.00 67.74  ? 37  LEU H CG  1 
ATOM 563  C CD1 . LEU B 2 37  ? 142.279 126.227 182.658 1.00 67.74  ? 37  LEU H CD1 1 
ATOM 564  C CD2 . LEU B 2 37  ? 142.620 128.071 181.016 1.00 67.74  ? 37  LEU H CD2 1 
ATOM 565  N N   . HIS B 2 38  ? 146.844 129.308 181.995 1.00 64.09  ? 38  HIS H N   1 
ATOM 566  C CA  . HIS B 2 38  ? 148.019 129.889 182.619 1.00 64.09  ? 38  HIS H CA  1 
ATOM 567  C C   . HIS B 2 38  ? 147.643 130.497 183.958 1.00 64.09  ? 38  HIS H C   1 
ATOM 568  O O   . HIS B 2 38  ? 146.549 131.042 184.126 1.00 64.09  ? 38  HIS H O   1 
ATOM 569  C CB  . HIS B 2 38  ? 148.657 130.961 181.726 1.00 64.09  ? 38  HIS H CB  1 
ATOM 570  C CG  . HIS B 2 38  ? 149.087 130.460 180.383 1.00 64.09  ? 38  HIS H CG  1 
ATOM 571  N ND1 . HIS B 2 38  ? 150.399 130.472 179.969 1.00 64.09  ? 38  HIS H ND1 1 
ATOM 572  C CD2 . HIS B 2 38  ? 148.374 129.938 179.358 1.00 64.09  ? 38  HIS H CD2 1 
ATOM 573  C CE1 . HIS B 2 38  ? 150.478 129.972 178.749 1.00 64.09  ? 38  HIS H CE1 1 
ATOM 574  N NE2 . HIS B 2 38  ? 149.263 129.639 178.357 1.00 64.09  ? 38  HIS H NE2 1 
ATOM 575  N N   . TRP B 2 39  ? 148.550 130.384 184.910 1.00 71.96  ? 39  TRP H N   1 
ATOM 576  C CA  . TRP B 2 39  ? 148.478 131.119 186.157 1.00 71.96  ? 39  TRP H CA  1 
ATOM 577  C C   . TRP B 2 39  ? 149.529 132.215 186.105 1.00 71.96  ? 39  TRP H C   1 
ATOM 578  O O   . TRP B 2 39  ? 150.696 131.952 185.785 1.00 71.96  ? 39  TRP H O   1 
ATOM 579  C CB  . TRP B 2 39  ? 148.700 130.198 187.362 1.00 71.96  ? 39  TRP H CB  1 
ATOM 580  C CG  . TRP B 2 39  ? 147.563 129.247 187.611 1.00 71.96  ? 39  TRP H CG  1 
ATOM 581  C CD1 . TRP B 2 39  ? 147.399 128.004 187.075 1.00 71.96  ? 39  TRP H CD1 1 
ATOM 582  C CD2 . TRP B 2 39  ? 146.431 129.468 188.459 1.00 71.96  ? 39  TRP H CD2 1 
ATOM 583  N NE1 . TRP B 2 39  ? 146.238 127.437 187.538 1.00 71.96  ? 39  TRP H NE1 1 
ATOM 584  C CE2 . TRP B 2 39  ? 145.625 128.316 188.388 1.00 71.96  ? 39  TRP H CE2 1 
ATOM 585  C CE3 . TRP B 2 39  ? 146.023 130.528 189.272 1.00 71.96  ? 39  TRP H CE3 1 
ATOM 586  C CZ2 . TRP B 2 39  ? 144.441 128.195 189.098 1.00 71.96  ? 39  TRP H CZ2 1 
ATOM 587  C CZ3 . TRP B 2 39  ? 144.845 130.405 189.971 1.00 71.96  ? 39  TRP H CZ3 1 
ATOM 588  C CH2 . TRP B 2 39  ? 144.067 129.248 189.880 1.00 71.96  ? 39  TRP H CH2 1 
ATOM 589  N N   . VAL B 2 40  ? 149.096 133.446 186.399 1.00 67.26  ? 40  VAL H N   1 
ATOM 590  C CA  . VAL B 2 40  ? 149.930 134.643 186.391 1.00 67.26  ? 40  VAL H CA  1 
ATOM 591  C C   . VAL B 2 40  ? 149.815 135.324 187.750 1.00 67.26  ? 40  VAL H C   1 
ATOM 592  O O   . VAL B 2 40  ? 148.717 135.472 188.294 1.00 67.26  ? 40  VAL H O   1 
ATOM 593  C CB  . VAL B 2 40  ? 149.529 135.618 185.260 1.00 67.26  ? 40  VAL H CB  1 
ATOM 594  C CG1 . VAL B 2 40  ? 150.501 136.782 185.183 1.00 67.26  ? 40  VAL H CG1 1 
ATOM 595  C CG2 . VAL B 2 40  ? 149.458 134.897 183.927 1.00 67.26  ? 40  VAL H CG2 1 
ATOM 596  N N   . ARG B 2 41  ? 150.947 135.755 188.287 1.00 73.09  ? 41  ARG H N   1 
ATOM 597  C CA  . ARG B 2 41  ? 151.067 136.257 189.643 1.00 73.09  ? 41  ARG H CA  1 
ATOM 598  C C   . ARG B 2 41  ? 151.343 137.754 189.620 1.00 73.09  ? 41  ARG H C   1 
ATOM 599  O O   . ARG B 2 41  ? 152.095 138.242 188.774 1.00 73.09  ? 41  ARG H O   1 
ATOM 600  C CB  . ARG B 2 41  ? 152.195 135.520 190.366 1.00 73.09  ? 41  ARG H CB  1 
ATOM 601  C CG  . ARG B 2 41  ? 152.300 135.734 191.845 1.00 73.09  ? 41  ARG H CG  1 
ATOM 602  C CD  . ARG B 2 41  ? 153.327 134.780 192.436 1.00 73.09  ? 41  ARG H CD  1 
ATOM 603  N NE  . ARG B 2 41  ? 154.664 134.988 191.896 1.00 73.09  ? 41  ARG H NE  1 
ATOM 604  C CZ  . ARG B 2 41  ? 155.715 134.243 192.207 1.00 73.09  ? 41  ARG H CZ  1 
ATOM 605  N NH1 . ARG B 2 41  ? 155.611 133.206 193.019 1.00 73.09  ? 41  ARG H NH1 1 
ATOM 606  N NH2 . ARG B 2 41  ? 156.902 134.548 191.693 1.00 73.09  ? 41  ARG H NH2 1 
ATOM 607  N N   . GLN B 2 42  ? 150.729 138.486 190.548 1.00 75.32  ? 42  GLN H N   1 
ATOM 608  C CA  . GLN B 2 42  ? 150.973 139.919 190.688 1.00 75.32  ? 42  GLN H CA  1 
ATOM 609  C C   . GLN B 2 42  ? 151.083 140.237 192.171 1.00 75.32  ? 42  GLN H C   1 
ATOM 610  O O   . GLN B 2 42  ? 150.102 140.116 192.907 1.00 75.32  ? 42  GLN H O   1 
ATOM 611  C CB  . GLN B 2 42  ? 149.869 140.752 190.038 1.00 75.32  ? 42  GLN H CB  1 
ATOM 612  C CG  . GLN B 2 42  ? 150.164 142.246 190.067 1.00 75.32  ? 42  GLN H CG  1 
ATOM 613  C CD  . GLN B 2 42  ? 149.050 143.078 189.480 1.00 75.32  ? 42  GLN H CD  1 
ATOM 614  O OE1 . GLN B 2 42  ? 147.876 142.738 189.610 1.00 75.32  ? 42  GLN H OE1 1 
ATOM 615  N NE2 . GLN B 2 42  ? 149.410 144.173 188.824 1.00 75.32  ? 42  GLN H NE2 1 
ATOM 616  N N   . ALA B 2 43  ? 152.274 140.615 192.611 1.00 82.09  ? 43  ALA H N   1 
ATOM 617  C CA  . ALA B 2 43  ? 152.436 141.048 193.982 1.00 82.09  ? 43  ALA H CA  1 
ATOM 618  C C   . ALA B 2 43  ? 151.765 142.407 194.176 1.00 82.09  ? 43  ALA H C   1 
ATOM 619  O O   . ALA B 2 43  ? 151.655 143.192 193.231 1.00 82.09  ? 43  ALA H O   1 
ATOM 620  C CB  . ALA B 2 43  ? 153.914 141.128 194.343 1.00 82.09  ? 43  ALA H CB  1 
ATOM 621  N N   . PRO B 2 44  ? 151.274 142.692 195.382 1.00 83.52  ? 44  PRO H N   1 
ATOM 622  C CA  . PRO B 2 44  ? 150.686 144.013 195.642 1.00 83.52  ? 44  PRO H CA  1 
ATOM 623  C C   . PRO B 2 44  ? 151.704 145.122 195.412 1.00 83.52  ? 44  PRO H C   1 
ATOM 624  O O   . PRO B 2 44  ? 152.812 145.094 195.949 1.00 83.52  ? 44  PRO H O   1 
ATOM 625  C CB  . PRO B 2 44  ? 150.263 143.927 197.112 1.00 83.52  ? 44  PRO H CB  1 
ATOM 626  C CG  . PRO B 2 44  ? 150.097 142.474 197.370 1.00 83.52  ? 44  PRO H CG  1 
ATOM 627  C CD  . PRO B 2 44  ? 151.142 141.795 196.541 1.00 83.52  ? 44  PRO H CD  1 
ATOM 628  N N   . GLY B 2 45  ? 151.316 146.103 194.602 1.00 81.49  ? 45  GLY H N   1 
ATOM 629  C CA  . GLY B 2 45  ? 152.218 147.167 194.224 1.00 81.49  ? 45  GLY H CA  1 
ATOM 630  C C   . GLY B 2 45  ? 153.197 146.808 193.129 1.00 81.49  ? 45  GLY H C   1 
ATOM 631  O O   . GLY B 2 45  ? 154.034 147.647 192.772 1.00 81.49  ? 45  GLY H O   1 
ATOM 632  N N   . LYS B 2 46  ? 153.125 145.595 192.592 1.00 82.13  ? 46  LYS H N   1 
ATOM 633  C CA  . LYS B 2 46  ? 154.037 145.111 191.569 1.00 82.13  ? 46  LYS H CA  1 
ATOM 634  C C   . LYS B 2 46  ? 153.271 144.800 190.288 1.00 82.13  ? 46  LYS H C   1 
ATOM 635  O O   . LYS B 2 46  ? 152.039 144.841 190.240 1.00 82.13  ? 46  LYS H O   1 
ATOM 636  C CB  . LYS B 2 46  ? 154.787 143.867 192.053 1.00 82.13  ? 46  LYS H CB  1 
ATOM 637  C CG  . LYS B 2 46  ? 155.616 144.084 193.306 1.00 82.13  ? 46  LYS H CG  1 
ATOM 638  C CD  . LYS B 2 46  ? 156.823 144.956 193.027 1.00 82.13  ? 46  LYS H CD  1 
ATOM 639  C CE  . LYS B 2 46  ? 157.748 145.007 194.230 1.00 82.13  ? 46  LYS H CE  1 
ATOM 640  N NZ  . LYS B 2 46  ? 158.984 145.788 193.950 1.00 82.13  ? 46  LYS H NZ  1 
ATOM 641  N N   . GLY B 2 47  ? 154.029 144.477 189.242 1.00 77.24  ? 47  GLY H N   1 
ATOM 642  C CA  . GLY B 2 47  ? 153.469 144.190 187.941 1.00 77.24  ? 47  GLY H CA  1 
ATOM 643  C C   . GLY B 2 47  ? 153.105 142.729 187.767 1.00 77.24  ? 47  GLY H C   1 
ATOM 644  O O   . GLY B 2 47  ? 153.069 141.941 188.713 1.00 77.24  ? 47  GLY H O   1 
ATOM 645  N N   . LEU B 2 48  ? 152.835 142.369 186.516 1.00 68.49  ? 48  LEU H N   1 
ATOM 646  C CA  . LEU B 2 48  ? 152.414 141.023 186.161 1.00 68.49  ? 48  LEU H CA  1 
ATOM 647  C C   . LEU B 2 48  ? 153.623 140.128 185.919 1.00 68.49  ? 48  LEU H C   1 
ATOM 648  O O   . LEU B 2 48  ? 154.588 140.528 185.263 1.00 68.49  ? 48  LEU H O   1 
ATOM 649  C CB  . LEU B 2 48  ? 151.527 141.057 184.919 1.00 68.49  ? 48  LEU H CB  1 
ATOM 650  C CG  . LEU B 2 48  ? 150.245 141.877 185.031 1.00 68.49  ? 48  LEU H CG  1 
ATOM 651  C CD1 . LEU B 2 48  ? 149.551 141.952 183.690 1.00 68.49  ? 48  LEU H CD1 1 
ATOM 652  C CD2 . LEU B 2 48  ? 149.328 141.269 186.063 1.00 68.49  ? 48  LEU H CD2 1 
ATOM 653  N N   . GLU B 2 49  ? 153.567 138.914 186.463 1.00 71.87  ? 49  GLU H N   1 
ATOM 654  C CA  . GLU B 2 49  ? 154.621 137.921 186.312 1.00 71.87  ? 49  GLU H CA  1 
ATOM 655  C C   . GLU B 2 49  ? 153.985 136.584 185.970 1.00 71.87  ? 49  GLU H C   1 
ATOM 656  O O   . GLU B 2 49  ? 153.157 136.080 186.725 1.00 71.87  ? 49  GLU H O   1 
ATOM 657  C CB  . GLU B 2 49  ? 155.455 137.799 187.589 1.00 71.87  ? 49  GLU H CB  1 
ATOM 658  C CG  . GLU B 2 49  ? 156.433 136.643 187.568 1.00 71.87  ? 49  GLU H CG  1 
ATOM 659  C CD  . GLU B 2 49  ? 156.927 136.273 188.948 1.00 71.87  ? 49  GLU H CD  1 
ATOM 660  O OE1 . GLU B 2 49  ? 156.336 136.752 189.938 1.00 71.87  ? 49  GLU H OE1 1 
ATOM 661  O OE2 . GLU B 2 49  ? 157.907 135.503 189.041 1.00 71.87  ? 49  GLU H OE2 1 
ATOM 662  N N   . TRP B 2 50  ? 154.388 136.003 184.844 1.00 65.62  ? 50  TRP H N   1 
ATOM 663  C CA  . TRP B 2 50  ? 153.887 134.691 184.462 1.00 65.62  ? 50  TRP H CA  1 
ATOM 664  C C   . TRP B 2 50  ? 154.426 133.634 185.406 1.00 65.62  ? 50  TRP H C   1 
ATOM 665  O O   . TRP B 2 50  ? 155.605 133.653 185.778 1.00 65.62  ? 50  TRP H O   1 
ATOM 666  C CB  . TRP B 2 50  ? 154.282 134.361 183.024 1.00 65.62  ? 50  TRP H CB  1 
ATOM 667  C CG  . TRP B 2 50  ? 153.765 133.039 182.545 1.00 65.62  ? 50  TRP H CG  1 
ATOM 668  C CD1 . TRP B 2 50  ? 152.494 132.758 182.139 1.00 65.62  ? 50  TRP H CD1 1 
ATOM 669  C CD2 . TRP B 2 50  ? 154.507 131.822 182.410 1.00 65.62  ? 50  TRP H CD2 1 
ATOM 670  N NE1 . TRP B 2 50  ? 152.398 131.444 181.763 1.00 65.62  ? 50  TRP H NE1 1 
ATOM 671  C CE2 . TRP B 2 50  ? 153.619 130.846 181.919 1.00 65.62  ? 50  TRP H CE2 1 
ATOM 672  C CE3 . TRP B 2 50  ? 155.834 131.462 182.657 1.00 65.62  ? 50  TRP H CE3 1 
ATOM 673  C CZ2 . TRP B 2 50  ? 154.014 129.536 181.673 1.00 65.62  ? 50  TRP H CZ2 1 
ATOM 674  C CZ3 . TRP B 2 50  ? 156.223 130.159 182.411 1.00 65.62  ? 50  TRP H CZ3 1 
ATOM 675  C CH2 . TRP B 2 50  ? 155.316 129.213 181.922 1.00 65.62  ? 50  TRP H CH2 1 
ATOM 676  N N   . VAL B 2 51  ? 153.559 132.702 185.806 1.00 66.59  ? 51  VAL H N   1 
ATOM 677  C CA  . VAL B 2 51  ? 153.923 131.642 186.731 1.00 66.59  ? 51  VAL H CA  1 
ATOM 678  C C   . VAL B 2 51  ? 153.993 130.292 186.023 1.00 66.59  ? 51  VAL H C   1 
ATOM 679  O O   . VAL B 2 51  ? 155.051 129.667 185.979 1.00 66.59  ? 51  VAL H O   1 
ATOM 680  C CB  . VAL B 2 51  ? 152.963 131.602 187.940 1.00 66.59  ? 51  VAL H CB  1 
ATOM 681  C CG1 . VAL B 2 51  ? 152.977 130.235 188.593 1.00 66.59  ? 51  VAL H CG1 1 
ATOM 682  C CG2 . VAL B 2 51  ? 153.394 132.633 188.944 1.00 66.59  ? 51  VAL H CG2 1 
ATOM 683  N N   . ALA B 2 52  ? 152.889 129.838 185.436 1.00 68.08  ? 52  ALA H N   1 
ATOM 684  C CA  . ALA B 2 52  ? 152.936 128.499 184.861 1.00 68.08  ? 52  ALA H CA  1 
ATOM 685  C C   . ALA B 2 52  ? 151.752 128.278 183.930 1.00 68.08  ? 52  ALA H C   1 
ATOM 686  O O   . ALA B 2 52  ? 150.826 129.086 183.876 1.00 68.08  ? 52  ALA H O   1 
ATOM 687  C CB  . ALA B 2 52  ? 152.971 127.436 185.958 1.00 68.08  ? 52  ALA H CB  1 
ATOM 688  N N   . TYR B 2 53  ? 151.806 127.176 183.177 1.00 71.05  ? 53  TYR H N   1 
ATOM 689  C CA  . TYR B 2 53  ? 150.731 126.838 182.251 1.00 71.05  ? 53  TYR H CA  1 
ATOM 690  C C   . TYR B 2 53  ? 150.602 125.329 182.111 1.00 71.05  ? 53  TYR H C   1 
ATOM 691  O O   . TYR B 2 53  ? 151.558 124.580 182.327 1.00 71.05  ? 53  TYR H O   1 
ATOM 692  C CB  . TYR B 2 53  ? 150.952 127.451 180.864 1.00 71.05  ? 53  TYR H CB  1 
ATOM 693  C CG  . TYR B 2 53  ? 151.416 126.468 179.801 1.00 71.05  ? 53  TYR H CG  1 
ATOM 694  C CD1 . TYR B 2 53  ? 152.756 126.145 179.669 1.00 71.05  ? 53  TYR H CD1 1 
ATOM 695  C CD2 . TYR B 2 53  ? 150.514 125.881 178.917 1.00 71.05  ? 53  TYR H CD2 1 
ATOM 696  C CE1 . TYR B 2 53  ? 153.184 125.256 178.703 1.00 71.05  ? 53  TYR H CE1 1 
ATOM 697  C CE2 . TYR B 2 53  ? 150.936 124.986 177.950 1.00 71.05  ? 53  TYR H CE2 1 
ATOM 698  C CZ  . TYR B 2 53  ? 152.272 124.681 177.846 1.00 71.05  ? 53  TYR H CZ  1 
ATOM 699  O OH  . TYR B 2 53  ? 152.698 123.796 176.882 1.00 71.05  ? 53  TYR H OH  1 
ATOM 700  N N   . ILE B 2 54  ? 149.405 124.900 181.706 1.00 78.80  ? 54  ILE H N   1 
ATOM 701  C CA  . ILE B 2 54  ? 149.113 123.502 181.415 1.00 78.80  ? 54  ILE H CA  1 
ATOM 702  C C   . ILE B 2 54  ? 148.260 123.411 180.155 1.00 78.80  ? 54  ILE H C   1 
ATOM 703  O O   . ILE B 2 54  ? 147.365 124.232 179.931 1.00 78.80  ? 54  ILE H O   1 
ATOM 704  C CB  . ILE B 2 54  ? 148.405 122.795 182.590 1.00 78.80  ? 54  ILE H CB  1 
ATOM 705  C CG1 . ILE B 2 54  ? 148.273 121.296 182.302 1.00 78.80  ? 54  ILE H CG1 1 
ATOM 706  C CG2 . ILE B 2 54  ? 147.037 123.414 182.845 1.00 78.80  ? 54  ILE H CG2 1 
ATOM 707  C CD1 . ILE B 2 54  ? 147.698 120.489 183.429 1.00 78.80  ? 54  ILE H CD1 1 
ATOM 708  N N   . SER B 2 55  ? 148.568 122.416 179.319 1.00 88.33  ? 55  SER H N   1 
ATOM 709  C CA  . SER B 2 55  ? 147.699 121.972 178.232 1.00 88.33  ? 55  SER H CA  1 
ATOM 710  C C   . SER B 2 55  ? 146.983 120.718 178.716 1.00 88.33  ? 55  SER H C   1 
ATOM 711  O O   . SER B 2 55  ? 147.535 119.617 178.674 1.00 88.33  ? 55  SER H O   1 
ATOM 712  C CB  . SER B 2 55  ? 148.492 121.701 176.962 1.00 88.33  ? 55  SER H CB  1 
ATOM 713  O OG  . SER B 2 55  ? 147.680 121.046 176.008 1.00 88.33  ? 55  SER H OG  1 
ATOM 714  N N   . SER B 2 56  ? 145.741 120.891 179.173 1.00 99.10  ? 56  SER H N   1 
ATOM 715  C CA  . SER B 2 56  ? 145.017 119.803 179.818 1.00 99.10  ? 56  SER H CA  1 
ATOM 716  C C   . SER B 2 56  ? 144.736 118.642 178.880 1.00 99.10  ? 56  SER H C   1 
ATOM 717  O O   . SER B 2 56  ? 144.490 117.528 179.354 1.00 99.10  ? 56  SER H O   1 
ATOM 718  C CB  . SER B 2 56  ? 143.695 120.317 180.387 1.00 99.10  ? 56  SER H CB  1 
ATOM 719  O OG  . SER B 2 56  ? 142.746 120.500 179.351 1.00 99.10  ? 56  SER H OG  1 
ATOM 720  N N   . SER B 2 57  ? 144.761 118.862 177.567 1.00 101.58 ? 57  SER H N   1 
ATOM 721  C CA  . SER B 2 57  ? 144.321 117.844 176.629 1.00 101.58 ? 57  SER H CA  1 
ATOM 722  C C   . SER B 2 57  ? 145.408 117.318 175.707 1.00 101.58 ? 57  SER H C   1 
ATOM 723  O O   . SER B 2 57  ? 145.255 116.209 175.184 1.00 101.58 ? 57  SER H O   1 
ATOM 724  C CB  . SER B 2 57  ? 143.171 118.378 175.763 1.00 101.58 ? 57  SER H CB  1 
ATOM 725  O OG  . SER B 2 57  ? 143.619 119.418 174.912 1.00 101.58 ? 57  SER H OG  1 
ATOM 726  N N   . SER B 2 58  ? 146.490 118.059 175.488 1.00 101.10 ? 58  SER H N   1 
ATOM 727  C CA  . SER B 2 58  ? 147.406 117.674 174.425 1.00 101.10 ? 58  SER H CA  1 
ATOM 728  C C   . SER B 2 58  ? 148.883 117.826 174.763 1.00 101.10 ? 58  SER H C   1 
ATOM 729  O O   . SER B 2 58  ? 149.718 117.613 173.876 1.00 101.10 ? 58  SER H O   1 
ATOM 730  C CB  . SER B 2 58  ? 147.100 118.474 173.153 1.00 101.10 ? 58  SER H CB  1 
ATOM 731  O OG  . SER B 2 58  ? 147.341 119.856 173.347 1.00 101.10 ? 58  SER H OG  1 
ATOM 732  N N   . GLY B 2 59  ? 149.252 118.169 175.986 1.00 95.65  ? 59  GLY H N   1 
ATOM 733  C CA  . GLY B 2 59  ? 150.656 118.403 176.237 1.00 95.65  ? 59  GLY H CA  1 
ATOM 734  C C   . GLY B 2 59  ? 151.021 118.506 177.699 1.00 95.65  ? 59  GLY H C   1 
ATOM 735  O O   . GLY B 2 59  ? 150.274 118.084 178.583 1.00 95.65  ? 59  GLY H O   1 
ATOM 736  N N   . SER B 2 60  ? 152.205 119.071 177.925 1.00 87.19  ? 60  SER H N   1 
ATOM 737  C CA  . SER B 2 60  ? 152.845 119.107 179.226 1.00 87.19  ? 60  SER H CA  1 
ATOM 738  C C   . SER B 2 60  ? 152.489 120.373 179.995 1.00 87.19  ? 60  SER H C   1 
ATOM 739  O O   . SER B 2 60  ? 151.737 121.238 179.540 1.00 87.19  ? 60  SER H O   1 
ATOM 740  C CB  . SER B 2 60  ? 154.363 119.009 179.079 1.00 87.19  ? 60  SER H CB  1 
ATOM 741  O OG  . SER B 2 60  ? 154.876 120.099 178.330 1.00 87.19  ? 60  SER H OG  1 
ATOM 742  N N   . THR B 2 61  ? 153.050 120.461 181.194 1.00 82.28  ? 61  THR H N   1 
ATOM 743  C CA  . THR B 2 61  ? 152.941 121.608 182.074 1.00 82.28  ? 61  THR H CA  1 
ATOM 744  C C   . THR B 2 61  ? 154.305 122.278 182.156 1.00 82.28  ? 61  THR H C   1 
ATOM 745  O O   . THR B 2 61  ? 155.332 121.596 182.215 1.00 82.28  ? 61  THR H O   1 
ATOM 746  C CB  . THR B 2 61  ? 152.474 121.169 183.466 1.00 82.28  ? 61  THR H CB  1 
ATOM 747  O OG1 . THR B 2 61  ? 151.202 120.519 183.362 1.00 82.28  ? 61  THR H OG1 1 
ATOM 748  C CG2 . THR B 2 61  ? 152.343 122.355 184.382 1.00 82.28  ? 61  THR H CG2 1 
ATOM 749  N N   . SER B 2 62  ? 154.321 123.612 182.138 1.00 77.02  ? 62  SER H N   1 
ATOM 750  C CA  . SER B 2 62  ? 155.565 124.367 182.238 1.00 77.02  ? 62  SER H CA  1 
ATOM 751  C C   . SER B 2 62  ? 155.470 125.377 183.374 1.00 77.02  ? 62  SER H C   1 
ATOM 752  O O   . SER B 2 62  ? 154.400 125.920 183.647 1.00 77.02  ? 62  SER H O   1 
ATOM 753  C CB  . SER B 2 62  ? 155.896 125.087 180.928 1.00 77.02  ? 62  SER H CB  1 
ATOM 754  O OG  . SER B 2 62  ? 157.192 125.653 180.983 1.00 77.02  ? 62  SER H OG  1 
ATOM 755  N N   . TYR B 2 63  ? 156.606 125.622 184.034 1.00 81.74  ? 63  TYR H N   1 
ATOM 756  C CA  . TYR B 2 63  ? 156.674 126.501 185.193 1.00 81.74  ? 63  TYR H CA  1 
ATOM 757  C C   . TYR B 2 63  ? 157.784 127.526 185.014 1.00 81.74  ? 63  TYR H C   1 
ATOM 758  O O   . TYR B 2 63  ? 158.784 127.274 184.337 1.00 81.74  ? 63  TYR H O   1 
ATOM 759  C CB  . TYR B 2 63  ? 156.934 125.724 186.499 1.00 81.74  ? 63  TYR H CB  1 
ATOM 760  C CG  . TYR B 2 63  ? 156.056 124.511 186.689 1.00 81.74  ? 63  TYR H CG  1 
ATOM 761  C CD1 . TYR B 2 63  ? 154.727 124.643 187.057 1.00 81.74  ? 63  TYR H CD1 1 
ATOM 762  C CD2 . TYR B 2 63  ? 156.558 123.232 186.498 1.00 81.74  ? 63  TYR H CD2 1 
ATOM 763  C CE1 . TYR B 2 63  ? 153.922 123.538 187.226 1.00 81.74  ? 63  TYR H CE1 1 
ATOM 764  C CE2 . TYR B 2 63  ? 155.759 122.120 186.667 1.00 81.74  ? 63  TYR H CE2 1 
ATOM 765  C CZ  . TYR B 2 63  ? 154.443 122.279 187.031 1.00 81.74  ? 63  TYR H CZ  1 
ATOM 766  O OH  . TYR B 2 63  ? 153.642 121.175 187.200 1.00 81.74  ? 63  TYR H OH  1 
ATOM 767  N N   . ALA B 2 64  ? 157.599 128.685 185.638 1.00 87.13  ? 64  ALA H N   1 
ATOM 768  C CA  . ALA B 2 64  ? 158.643 129.697 185.669 1.00 87.13  ? 64  ALA H CA  1 
ATOM 769  C C   . ALA B 2 64  ? 159.802 129.233 186.538 1.00 87.13  ? 64  ALA H C   1 
ATOM 770  O O   . ALA B 2 64  ? 159.637 128.420 187.449 1.00 87.13  ? 64  ALA H O   1 
ATOM 771  C CB  . ALA B 2 64  ? 158.092 131.020 186.194 1.00 87.13  ? 64  ALA H CB  1 
ATOM 772  N N   . ASP B 2 65  ? 160.993 129.755 186.239 1.00 102.32 ? 65  ASP H N   1 
ATOM 773  C CA  . ASP B 2 65  ? 162.165 129.426 187.043 1.00 102.32 ? 65  ASP H CA  1 
ATOM 774  C C   . ASP B 2 65  ? 161.969 129.803 188.506 1.00 102.32 ? 65  ASP H C   1 
ATOM 775  O O   . ASP B 2 65  ? 162.572 129.185 189.391 1.00 102.32 ? 65  ASP H O   1 
ATOM 776  C CB  . ASP B 2 65  ? 163.404 130.127 186.482 1.00 102.32 ? 65  ASP H CB  1 
ATOM 777  C CG  . ASP B 2 65  ? 163.914 129.479 185.212 1.00 102.32 ? 65  ASP H CG  1 
ATOM 778  O OD1 . ASP B 2 65  ? 163.304 128.484 184.763 1.00 102.32 ? 65  ASP H OD1 1 
ATOM 779  O OD2 . ASP B 2 65  ? 164.927 129.963 184.664 1.00 102.32 ? 65  ASP H OD2 1 
ATOM 780  N N   . SER B 2 66  ? 161.135 130.808 188.781 1.00 101.80 ? 66  SER H N   1 
ATOM 781  C CA  . SER B 2 66  ? 160.900 131.239 190.154 1.00 101.80 ? 66  SER H CA  1 
ATOM 782  C C   . SER B 2 66  ? 160.115 130.218 190.964 1.00 101.80 ? 66  SER H C   1 
ATOM 783  O O   . SER B 2 66  ? 160.181 130.244 192.197 1.00 101.80 ? 66  SER H O   1 
ATOM 784  C CB  . SER B 2 66  ? 160.163 132.578 190.163 1.00 101.80 ? 66  SER H CB  1 
ATOM 785  O OG  . SER B 2 66  ? 158.909 132.469 189.510 1.00 101.80 ? 66  SER H OG  1 
ATOM 786  N N   . VAL B 2 67  ? 159.380 129.320 190.311 1.00 98.49  ? 67  VAL H N   1 
ATOM 787  C CA  . VAL B 2 67  ? 158.544 128.351 191.007 1.00 98.49  ? 67  VAL H CA  1 
ATOM 788  C C   . VAL B 2 67  ? 158.881 126.910 190.659 1.00 98.49  ? 67  VAL H C   1 
ATOM 789  O O   . VAL B 2 67  ? 158.229 125.998 191.176 1.00 98.49  ? 67  VAL H O   1 
ATOM 790  C CB  . VAL B 2 67  ? 157.044 128.613 190.760 1.00 98.49  ? 67  VAL H CB  1 
ATOM 791  C CG1 . VAL B 2 67  ? 156.701 130.066 191.029 1.00 98.49  ? 67  VAL H CG1 1 
ATOM 792  C CG2 . VAL B 2 67  ? 156.657 128.219 189.347 1.00 98.49  ? 67  VAL H CG2 1 
ATOM 793  N N   . LYS B 2 68  ? 159.862 126.673 189.784 1.00 105.31 ? 68  LYS H N   1 
ATOM 794  C CA  . LYS B 2 68  ? 160.242 125.309 189.432 1.00 105.31 ? 68  LYS H CA  1 
ATOM 795  C C   . LYS B 2 68  ? 160.685 124.540 190.668 1.00 105.31 ? 68  LYS H C   1 
ATOM 796  O O   . LYS B 2 68  ? 161.472 125.039 191.479 1.00 105.31 ? 68  LYS H O   1 
ATOM 797  C CB  . LYS B 2 68  ? 161.361 125.318 188.389 1.00 105.31 ? 68  LYS H CB  1 
ATOM 798  C CG  . LYS B 2 68  ? 160.878 125.404 186.949 1.00 105.31 ? 68  LYS H CG  1 
ATOM 799  C CD  . LYS B 2 68  ? 162.043 125.356 185.970 1.00 105.31 ? 68  LYS H CD  1 
ATOM 800  C CE  . LYS B 2 68  ? 161.559 125.468 184.533 1.00 105.31 ? 68  LYS H CE  1 
ATOM 801  N NZ  . LYS B 2 68  ? 162.684 125.537 183.561 1.00 105.31 ? 68  LYS H NZ  1 
ATOM 802  N N   . GLY B 2 69  ? 160.173 123.320 190.808 1.00 107.61 ? 69  GLY H N   1 
ATOM 803  C CA  . GLY B 2 69  ? 160.444 122.496 191.960 1.00 107.61 ? 69  GLY H CA  1 
ATOM 804  C C   . GLY B 2 69  ? 159.466 122.655 193.102 1.00 107.61 ? 69  GLY H C   1 
ATOM 805  O O   . GLY B 2 69  ? 159.520 121.866 194.053 1.00 107.61 ? 69  GLY H O   1 
ATOM 806  N N   . ARG B 2 70  ? 158.573 123.638 193.042 1.00 109.13 ? 70  ARG H N   1 
ATOM 807  C CA  . ARG B 2 70  ? 157.632 123.886 194.127 1.00 109.13 ? 70  ARG H CA  1 
ATOM 808  C C   . ARG B 2 70  ? 156.176 123.858 193.692 1.00 109.13 ? 70  ARG H C   1 
ATOM 809  O O   . ARG B 2 70  ? 155.338 123.304 194.404 1.00 109.13 ? 70  ARG H O   1 
ATOM 810  C CB  . ARG B 2 70  ? 157.935 125.236 194.784 1.00 109.13 ? 70  ARG H CB  1 
ATOM 811  C CG  . ARG B 2 70  ? 159.379 125.423 195.186 1.00 109.13 ? 70  ARG H CG  1 
ATOM 812  C CD  . ARG B 2 70  ? 159.529 126.738 195.908 1.00 109.13 ? 70  ARG H CD  1 
ATOM 813  N NE  . ARG B 2 70  ? 158.795 127.795 195.223 1.00 109.13 ? 70  ARG H NE  1 
ATOM 814  C CZ  . ARG B 2 70  ? 158.477 128.958 195.772 1.00 109.13 ? 70  ARG H CZ  1 
ATOM 815  N NH1 . ARG B 2 70  ? 158.790 129.239 197.025 1.00 109.13 ? 70  ARG H NH1 1 
ATOM 816  N NH2 . ARG B 2 70  ? 157.827 129.862 195.045 1.00 109.13 ? 70  ARG H NH2 1 
ATOM 817  N N   . PHE B 2 71  ? 155.849 124.438 192.543 1.00 99.62  ? 71  PHE H N   1 
ATOM 818  C CA  . PHE B 2 71  ? 154.473 124.508 192.080 1.00 99.62  ? 71  PHE H CA  1 
ATOM 819  C C   . PHE B 2 71  ? 154.182 123.353 191.132 1.00 99.62  ? 71  PHE H C   1 
ATOM 820  O O   . PHE B 2 71  ? 155.051 122.913 190.375 1.00 99.62  ? 71  PHE H O   1 
ATOM 821  C CB  . PHE B 2 71  ? 154.181 125.834 191.367 1.00 99.62  ? 71  PHE H CB  1 
ATOM 822  C CG  . PHE B 2 71  ? 154.159 127.040 192.273 1.00 99.62  ? 71  PHE H CG  1 
ATOM 823  C CD1 . PHE B 2 71  ? 154.697 126.999 193.550 1.00 99.62  ? 71  PHE H CD1 1 
ATOM 824  C CD2 . PHE B 2 71  ? 153.586 128.221 191.836 1.00 99.62  ? 71  PHE H CD2 1 
ATOM 825  C CE1 . PHE B 2 71  ? 154.674 128.116 194.364 1.00 99.62  ? 71  PHE H CE1 1 
ATOM 826  C CE2 . PHE B 2 71  ? 153.556 129.338 192.646 1.00 99.62  ? 71  PHE H CE2 1 
ATOM 827  C CZ  . PHE B 2 71  ? 154.101 129.285 193.911 1.00 99.62  ? 71  PHE H CZ  1 
ATOM 828  N N   . THR B 2 72  ? 152.950 122.860 191.186 1.00 94.19  ? 72  THR H N   1 
ATOM 829  C CA  . THR B 2 72  ? 152.495 121.801 190.302 1.00 94.19  ? 72  THR H CA  1 
ATOM 830  C C   . THR B 2 72  ? 151.128 122.164 189.754 1.00 94.19  ? 72  THR H C   1 
ATOM 831  O O   . THR B 2 72  ? 150.214 122.475 190.520 1.00 94.19  ? 72  THR H O   1 
ATOM 832  C CB  . THR B 2 72  ? 152.433 120.457 191.034 1.00 94.19  ? 72  THR H CB  1 
ATOM 833  O OG1 . THR B 2 72  ? 153.749 119.894 191.114 1.00 94.19  ? 72  THR H OG1 1 
ATOM 834  C CG2 . THR B 2 72  ? 151.506 119.490 190.317 1.00 94.19  ? 72  THR H CG2 1 
ATOM 835  N N   . ILE B 2 73  ? 150.976 122.111 188.436 1.00 82.57  ? 73  ILE H N   1 
ATOM 836  C CA  . ILE B 2 73  ? 149.711 122.431 187.791 1.00 82.57  ? 73  ILE H CA  1 
ATOM 837  C C   . ILE B 2 73  ? 149.098 121.146 187.267 1.00 82.57  ? 73  ILE H C   1 
ATOM 838  O O   . ILE B 2 73  ? 149.776 120.348 186.611 1.00 82.57  ? 73  ILE H O   1 
ATOM 839  C CB  . ILE B 2 73  ? 149.868 123.448 186.650 1.00 82.57  ? 73  ILE H CB  1 
ATOM 840  C CG1 . ILE B 2 73  ? 150.417 124.772 187.159 1.00 82.57  ? 73  ILE H CG1 1 
ATOM 841  C CG2 . ILE B 2 73  ? 148.521 123.698 186.009 1.00 82.57  ? 73  ILE H CG2 1 
ATOM 842  C CD1 . ILE B 2 73  ? 149.975 125.945 186.311 1.00 82.57  ? 73  ILE H CD1 1 
ATOM 843  N N   . SER B 2 74  ? 147.823 120.949 187.556 1.00 89.55  ? 74  SER H N   1 
ATOM 844  C CA  . SER B 2 74  ? 147.077 119.818 187.046 1.00 89.55  ? 74  SER H CA  1 
ATOM 845  C C   . SER B 2 74  ? 145.745 120.324 186.536 1.00 89.55  ? 74  SER H C   1 
ATOM 846  O O   . SER B 2 74  ? 145.417 121.503 186.663 1.00 89.55  ? 74  SER H O   1 
ATOM 847  C CB  . SER B 2 74  ? 146.870 118.743 188.119 1.00 89.55  ? 74  SER H CB  1 
ATOM 848  O OG  . SER B 2 74  ? 146.174 119.270 189.235 1.00 89.55  ? 74  SER H OG  1 
ATOM 849  N N   . ALA B 2 75  ? 144.962 119.420 185.969 1.00 95.45  ? 75  ALA H N   1 
ATOM 850  C CA  . ALA B 2 75  ? 143.672 119.805 185.439 1.00 95.45  ? 75  ALA H CA  1 
ATOM 851  C C   . ALA B 2 75  ? 142.759 118.596 185.446 1.00 95.45  ? 75  ALA H C   1 
ATOM 852  O O   . ALA B 2 75  ? 143.211 117.452 185.525 1.00 95.45  ? 75  ALA H O   1 
ATOM 853  C CB  . ALA B 2 75  ? 143.795 120.380 184.027 1.00 95.45  ? 75  ALA H CB  1 
ATOM 854  N N   . ASP B 2 76  ? 141.463 118.867 185.365 1.00 103.20 ? 76  ASP H N   1 
ATOM 855  C CA  . ASP B 2 76  ? 140.440 117.833 185.303 1.00 103.20 ? 76  ASP H CA  1 
ATOM 856  C C   . ASP B 2 76  ? 139.488 118.213 184.181 1.00 103.20 ? 76  ASP H C   1 
ATOM 857  O O   . ASP B 2 76  ? 138.743 119.194 184.298 1.00 103.20 ? 76  ASP H O   1 
ATOM 858  C CB  . ASP B 2 76  ? 139.710 117.697 186.639 1.00 103.20 ? 76  ASP H CB  1 
ATOM 859  C CG  . ASP B 2 76  ? 138.868 116.442 186.717 1.00 103.20 ? 76  ASP H CG  1 
ATOM 860  O OD1 . ASP B 2 76  ? 138.265 116.066 185.692 1.00 103.20 ? 76  ASP H OD1 1 
ATOM 861  O OD2 . ASP B 2 76  ? 138.811 115.826 187.803 1.00 103.20 ? 76  ASP H OD2 1 
ATOM 862  N N   . THR B 2 77  ? 139.530 117.448 183.091 1.00 105.60 ? 77  THR H N   1 
ATOM 863  C CA  . THR B 2 77  ? 138.711 117.726 181.922 1.00 105.60 ? 77  THR H CA  1 
ATOM 864  C C   . THR B 2 77  ? 137.258 117.308 182.102 1.00 105.60 ? 77  THR H C   1 
ATOM 865  O O   . THR B 2 77  ? 136.412 117.722 181.302 1.00 105.60 ? 77  THR H O   1 
ATOM 866  C CB  . THR B 2 77  ? 139.299 117.032 180.690 1.00 105.60 ? 77  THR H CB  1 
ATOM 867  O OG1 . THR B 2 77  ? 139.286 115.613 180.888 1.00 105.60 ? 77  THR H OG1 1 
ATOM 868  C CG2 . THR B 2 77  ? 140.733 117.492 180.449 1.00 105.60 ? 77  THR H CG2 1 
ATOM 869  N N   . SER B 2 78  ? 136.944 116.512 183.124 1.00 106.32 ? 78  SER H N   1 
ATOM 870  C CA  . SER B 2 78  ? 135.558 116.165 183.417 1.00 106.32 ? 78  SER H CA  1 
ATOM 871  C C   . SER B 2 78  ? 134.910 117.140 184.387 1.00 106.32 ? 78  SER H C   1 
ATOM 872  O O   . SER B 2 78  ? 133.691 117.335 184.340 1.00 106.32 ? 78  SER H O   1 
ATOM 873  C CB  . SER B 2 78  ? 135.467 114.748 183.986 1.00 106.32 ? 78  SER H CB  1 
ATOM 874  O OG  . SER B 2 78  ? 135.872 114.719 185.343 1.00 106.32 ? 78  SER H OG  1 
ATOM 875  N N   . LYS B 2 79  ? 135.693 117.747 185.275 1.00 105.37 ? 79  LYS H N   1 
ATOM 876  C CA  . LYS B 2 79  ? 135.211 118.862 186.073 1.00 105.37 ? 79  LYS H CA  1 
ATOM 877  C C   . LYS B 2 79  ? 135.423 120.196 185.378 1.00 105.37 ? 79  LYS H C   1 
ATOM 878  O O   . LYS B 2 79  ? 134.932 121.218 185.867 1.00 105.37 ? 79  LYS H O   1 
ATOM 879  C CB  . LYS B 2 79  ? 135.905 118.885 187.438 1.00 105.37 ? 79  LYS H CB  1 
ATOM 880  C CG  . LYS B 2 79  ? 135.562 117.708 188.330 1.00 105.37 ? 79  LYS H CG  1 
ATOM 881  C CD  . LYS B 2 79  ? 136.267 117.800 189.674 1.00 105.37 ? 79  LYS H CD  1 
ATOM 882  C CE  . LYS B 2 79  ? 136.038 116.537 190.480 1.00 105.37 ? 79  LYS H CE  1 
ATOM 883  N NZ  . LYS B 2 79  ? 136.529 115.344 189.737 1.00 105.37 ? 79  LYS H NZ  1 
ATOM 884  N N   . ASN B 2 80  ? 136.143 120.195 184.255 1.00 99.80  ? 80  ASN H N   1 
ATOM 885  C CA  . ASN B 2 80  ? 136.445 121.398 183.483 1.00 99.80  ? 80  ASN H CA  1 
ATOM 886  C C   . ASN B 2 80  ? 137.154 122.438 184.346 1.00 99.80  ? 80  ASN H C   1 
ATOM 887  O O   . ASN B 2 80  ? 136.832 123.627 184.320 1.00 99.80  ? 80  ASN H O   1 
ATOM 888  C CB  . ASN B 2 80  ? 135.180 121.976 182.846 1.00 99.80  ? 80  ASN H CB  1 
ATOM 889  C CG  . ASN B 2 80  ? 135.487 123.002 181.780 1.00 99.80  ? 80  ASN H CG  1 
ATOM 890  O OD1 . ASN B 2 80  ? 136.587 123.026 181.231 1.00 99.80  ? 80  ASN H OD1 1 
ATOM 891  N ND2 . ASN B 2 80  ? 134.521 123.862 181.485 1.00 99.80  ? 80  ASN H ND2 1 
ATOM 892  N N   . THR B 2 81  ? 138.136 121.979 185.117 1.00 96.19  ? 81  THR H N   1 
ATOM 893  C CA  . THR B 2 81  ? 138.822 122.832 186.076 1.00 96.19  ? 81  THR H CA  1 
ATOM 894  C C   . THR B 2 81  ? 140.326 122.644 185.957 1.00 96.19  ? 81  THR H C   1 
ATOM 895  O O   . THR B 2 81  ? 140.811 121.683 185.358 1.00 96.19  ? 81  THR H O   1 
ATOM 896  C CB  . THR B 2 81  ? 138.377 122.532 187.515 1.00 96.19  ? 81  THR H CB  1 
ATOM 897  O OG1 . THR B 2 81  ? 138.525 121.131 187.777 1.00 96.19  ? 81  THR H OG1 1 
ATOM 898  C CG2 . THR B 2 81  ? 136.928 122.930 187.732 1.00 96.19  ? 81  THR H CG2 1 
ATOM 899  N N   . ALA B 2 82  ? 141.069 123.570 186.554 1.00 92.18  ? 82  ALA H N   1 
ATOM 900  C CA  . ALA B 2 82  ? 142.511 123.455 186.672 1.00 92.18  ? 82  ALA H CA  1 
ATOM 901  C C   . ALA B 2 82  ? 142.901 123.753 188.107 1.00 92.18  ? 82  ALA H C   1 
ATOM 902  O O   . ALA B 2 82  ? 142.189 124.459 188.821 1.00 92.18  ? 82  ALA H O   1 
ATOM 903  C CB  . ALA B 2 82  ? 143.249 124.405 185.726 1.00 92.18  ? 82  ALA H CB  1 
ATOM 904  N N   . TYR B 2 83  ? 144.024 123.195 188.534 1.00 92.34  ? 83  TYR H N   1 
ATOM 905  C CA  . TYR B 2 83  ? 144.511 123.389 189.887 1.00 92.34  ? 83  TYR H CA  1 
ATOM 906  C C   . TYR B 2 83  ? 145.979 123.765 189.853 1.00 92.34  ? 83  TYR H C   1 
ATOM 907  O O   . TYR B 2 83  ? 146.750 123.242 189.040 1.00 92.34  ? 83  TYR H O   1 
ATOM 908  C CB  . TYR B 2 83  ? 144.327 122.131 190.744 1.00 92.34  ? 83  TYR H CB  1 
ATOM 909  C CG  . TYR B 2 83  ? 142.926 121.587 190.736 1.00 92.34  ? 83  TYR H CG  1 
ATOM 910  C CD1 . TYR B 2 83  ? 141.957 122.111 191.573 1.00 92.34  ? 83  TYR H CD1 1 
ATOM 911  C CD2 . TYR B 2 83  ? 142.570 120.550 189.892 1.00 92.34  ? 83  TYR H CD2 1 
ATOM 912  C CE1 . TYR B 2 83  ? 140.672 121.619 191.572 1.00 92.34  ? 83  TYR H CE1 1 
ATOM 913  C CE2 . TYR B 2 83  ? 141.286 120.048 189.883 1.00 92.34  ? 83  TYR H CE2 1 
ATOM 914  C CZ  . TYR B 2 83  ? 140.341 120.588 190.727 1.00 92.34  ? 83  TYR H CZ  1 
ATOM 915  O OH  . TYR B 2 83  ? 139.057 120.097 190.728 1.00 92.34  ? 83  TYR H OH  1 
ATOM 916  N N   . LEU B 2 84  ? 146.357 124.667 190.747 1.00 90.58  ? 84  LEU H N   1 
ATOM 917  C CA  . LEU B 2 84  ? 147.753 124.974 191.016 1.00 90.58  ? 84  LEU H CA  1 
ATOM 918  C C   . LEU B 2 84  ? 148.020 124.678 192.482 1.00 90.58  ? 84  LEU H C   1 
ATOM 919  O O   . LEU B 2 84  ? 147.407 125.286 193.363 1.00 90.58  ? 84  LEU H O   1 
ATOM 920  C CB  . LEU B 2 84  ? 148.086 126.430 190.685 1.00 90.58  ? 84  LEU H CB  1 
ATOM 921  C CG  . LEU B 2 84  ? 149.479 126.900 191.124 1.00 90.58  ? 84  LEU H CG  1 
ATOM 922  C CD1 . LEU B 2 84  ? 150.566 125.994 190.580 1.00 90.58  ? 84  LEU H CD1 1 
ATOM 923  C CD2 . LEU B 2 84  ? 149.739 128.340 190.716 1.00 90.58  ? 84  LEU H CD2 1 
ATOM 924  N N   . GLN B 2 85  ? 148.922 123.744 192.740 1.00 100.45 ? 85  GLN H N   1 
ATOM 925  C CA  . GLN B 2 85  ? 149.313 123.380 194.090 1.00 100.45 ? 85  GLN H CA  1 
ATOM 926  C C   . GLN B 2 85  ? 150.682 123.968 194.377 1.00 100.45 ? 85  GLN H C   1 
ATOM 927  O O   . GLN B 2 85  ? 151.633 123.735 193.625 1.00 100.45 ? 85  GLN H O   1 
ATOM 928  C CB  . GLN B 2 85  ? 149.345 121.863 194.264 1.00 100.45 ? 85  GLN H CB  1 
ATOM 929  C CG  . GLN B 2 85  ? 150.224 121.402 195.406 1.00 100.45 ? 85  GLN H CG  1 
ATOM 930  C CD  . GLN B 2 85  ? 149.475 120.542 196.391 1.00 100.45 ? 85  GLN H CD  1 
ATOM 931  O OE1 . GLN B 2 85  ? 148.336 120.149 196.145 1.00 100.45 ? 85  GLN H OE1 1 
ATOM 932  N NE2 . GLN B 2 85  ? 150.109 120.240 197.516 1.00 100.45 ? 85  GLN H NE2 1 
ATOM 933  N N   . MET B 2 86  ? 150.778 124.727 195.463 1.00 104.76 ? 86  MET H N   1 
ATOM 934  C CA  . MET B 2 86  ? 151.996 125.419 195.842 1.00 104.76 ? 86  MET H CA  1 
ATOM 935  C C   . MET B 2 86  ? 152.464 124.862 197.172 1.00 104.76 ? 86  MET H C   1 
ATOM 936  O O   . MET B 2 86  ? 151.713 124.876 198.154 1.00 104.76 ? 86  MET H O   1 
ATOM 937  C CB  . MET B 2 86  ? 151.759 126.925 195.934 1.00 104.76 ? 86  MET H CB  1 
ATOM 938  C CG  . MET B 2 86  ? 151.230 127.533 194.653 1.00 104.76 ? 86  MET H CG  1 
ATOM 939  S SD  . MET B 2 86  ? 150.657 129.232 194.857 1.00 104.76 ? 86  MET H SD  1 
ATOM 940  C CE  . MET B 2 86  ? 149.255 128.995 195.943 1.00 104.76 ? 86  MET H CE  1 
ATOM 941  N N   . ASN B 2 87  ? 153.691 124.358 197.191 1.00 112.02 ? 87  ASN H N   1 
ATOM 942  C CA  . ASN B 2 87  ? 154.335 123.833 198.381 1.00 112.02 ? 87  ASN H CA  1 
ATOM 943  C C   . ASN B 2 87  ? 155.573 124.659 198.695 1.00 112.02 ? 87  ASN H C   1 
ATOM 944  O O   . ASN B 2 87  ? 156.170 125.275 197.811 1.00 112.02 ? 87  ASN H O   1 
ATOM 945  C CB  . ASN B 2 87  ? 154.725 122.366 198.189 1.00 112.02 ? 87  ASN H CB  1 
ATOM 946  C CG  . ASN B 2 87  ? 153.624 121.555 197.538 1.00 112.02 ? 87  ASN H CG  1 
ATOM 947  O OD1 . ASN B 2 87  ? 152.440 121.844 197.705 1.00 112.02 ? 87  ASN H OD1 1 
ATOM 948  N ND2 . ASN B 2 87  ? 154.011 120.532 196.787 1.00 112.02 ? 87  ASN H ND2 1 
ATOM 949  N N   . SER B 2 88  ? 155.960 124.647 199.972 1.00 115.60 ? 88  SER H N   1 
ATOM 950  C CA  . SER B 2 88  ? 157.101 125.424 200.462 1.00 115.60 ? 88  SER H CA  1 
ATOM 951  C C   . SER B 2 88  ? 156.936 126.903 200.126 1.00 115.60 ? 88  SER H C   1 
ATOM 952  O O   . SER B 2 88  ? 157.877 127.578 199.702 1.00 115.60 ? 88  SER H O   1 
ATOM 953  C CB  . SER B 2 88  ? 158.417 124.874 199.919 1.00 115.60 ? 88  SER H CB  1 
ATOM 954  O OG  . SER B 2 88  ? 158.586 123.524 200.309 1.00 115.60 ? 88  SER H OG  1 
ATOM 955  N N   . LEU B 2 89  ? 155.718 127.402 200.316 1.00 112.34 ? 89  LEU H N   1 
ATOM 956  C CA  . LEU B 2 89  ? 155.416 128.793 200.019 1.00 112.34 ? 89  LEU H CA  1 
ATOM 957  C C   . LEU B 2 89  ? 156.221 129.719 200.917 1.00 112.34 ? 89  LEU H C   1 
ATOM 958  O O   . LEU B 2 89  ? 156.432 129.438 202.100 1.00 112.34 ? 89  LEU H O   1 
ATOM 959  C CB  . LEU B 2 89  ? 153.921 129.056 200.196 1.00 112.34 ? 89  LEU H CB  1 
ATOM 960  C CG  . LEU B 2 89  ? 152.997 128.634 199.054 1.00 112.34 ? 89  LEU H CG  1 
ATOM 961  C CD1 . LEU B 2 89  ? 151.548 128.594 199.504 1.00 112.34 ? 89  LEU H CD1 1 
ATOM 962  C CD2 . LEU B 2 89  ? 153.157 129.580 197.879 1.00 112.34 ? 89  LEU H CD2 1 
ATOM 963  N N   . ARG B 2 90  ? 156.682 130.824 200.344 1.00 113.48 ? 90  ARG H N   1 
ATOM 964  C CA  . ARG B 2 90  ? 157.393 131.864 201.072 1.00 113.48 ? 90  ARG H CA  1 
ATOM 965  C C   . ARG B 2 90  ? 156.529 133.112 201.155 1.00 113.48 ? 90  ARG H C   1 
ATOM 966  O O   . ARG B 2 90  ? 155.519 133.246 200.456 1.00 113.48 ? 90  ARG H O   1 
ATOM 967  C CB  . ARG B 2 90  ? 158.724 132.203 200.396 1.00 113.48 ? 90  ARG H CB  1 
ATOM 968  C CG  . ARG B 2 90  ? 159.613 131.013 200.132 1.00 113.48 ? 90  ARG H CG  1 
ATOM 969  C CD  . ARG B 2 90  ? 160.847 131.434 199.360 1.00 113.48 ? 90  ARG H CD  1 
ATOM 970  N NE  . ARG B 2 90  ? 161.653 130.290 198.954 1.00 113.48 ? 90  ARG H NE  1 
ATOM 971  C CZ  . ARG B 2 90  ? 162.741 130.372 198.200 1.00 113.48 ? 90  ARG H CZ  1 
ATOM 972  N NH1 . ARG B 2 90  ? 163.186 131.535 197.752 1.00 113.48 ? 90  ARG H NH1 1 
ATOM 973  N NH2 . ARG B 2 90  ? 163.398 129.259 197.888 1.00 113.48 ? 90  ARG H NH2 1 
ATOM 974  N N   . ALA B 2 91  ? 156.945 134.040 202.021 1.00 113.23 ? 91  ALA H N   1 
ATOM 975  C CA  . ALA B 2 91  ? 156.299 135.347 202.052 1.00 113.23 ? 91  ALA H CA  1 
ATOM 976  C C   . ALA B 2 91  ? 156.412 136.050 200.705 1.00 113.23 ? 91  ALA H C   1 
ATOM 977  O O   . ALA B 2 91  ? 155.529 136.837 200.336 1.00 113.23 ? 91  ALA H O   1 
ATOM 978  C CB  . ALA B 2 91  ? 156.907 136.207 203.161 1.00 113.23 ? 91  ALA H CB  1 
ATOM 979  N N   . GLU B 2 92  ? 157.474 135.759 199.946 1.00 111.82 ? 92  GLU H N   1 
ATOM 980  C CA  . GLU B 2 92  ? 157.654 136.346 198.623 1.00 111.82 ? 92  GLU H CA  1 
ATOM 981  C C   . GLU B 2 92  ? 156.551 135.951 197.650 1.00 111.82 ? 92  GLU H C   1 
ATOM 982  O O   . GLU B 2 92  ? 156.336 136.655 196.658 1.00 111.82 ? 92  GLU H O   1 
ATOM 983  C CB  . GLU B 2 92  ? 159.012 135.935 198.052 1.00 111.82 ? 92  GLU H CB  1 
ATOM 984  C CG  . GLU B 2 92  ? 160.191 136.278 198.946 1.00 111.82 ? 92  GLU H CG  1 
ATOM 985  C CD  . GLU B 2 92  ? 161.485 135.629 198.492 1.00 111.82 ? 92  GLU H CD  1 
ATOM 986  O OE1 . GLU B 2 92  ? 161.462 134.875 197.497 1.00 111.82 ? 92  GLU H OE1 1 
ATOM 987  O OE2 . GLU B 2 92  ? 162.527 135.875 199.136 1.00 111.82 ? 92  GLU H OE2 1 
ATOM 988  N N   . ASP B 2 93  ? 155.859 134.842 197.900 1.00 105.35 ? 93  ASP H N   1 
ATOM 989  C CA  . ASP B 2 93  ? 154.799 134.389 197.008 1.00 105.35 ? 93  ASP H CA  1 
ATOM 990  C C   . ASP B 2 93  ? 153.453 135.012 197.333 1.00 105.35 ? 93  ASP H C   1 
ATOM 991  O O   . ASP B 2 93  ? 152.477 134.738 196.626 1.00 105.35 ? 93  ASP H O   1 
ATOM 992  C CB  . ASP B 2 93  ? 154.670 132.863 197.065 1.00 105.35 ? 93  ASP H CB  1 
ATOM 993  C CG  . ASP B 2 93  ? 155.950 132.150 196.683 1.00 105.35 ? 93  ASP H CG  1 
ATOM 994  O OD1 . ASP B 2 93  ? 156.657 132.636 195.776 1.00 105.35 ? 93  ASP H OD1 1 
ATOM 995  O OD2 . ASP B 2 93  ? 156.247 131.101 197.291 1.00 105.35 ? 93  ASP H OD2 1 
ATOM 996  N N   . THR B 2 94  ? 153.371 135.815 198.397 1.00 101.39 ? 94  THR H N   1 
ATOM 997  C CA  . THR B 2 94  ? 152.128 136.515 198.694 1.00 101.39 ? 94  THR H CA  1 
ATOM 998  C C   . THR B 2 94  ? 151.778 137.435 197.537 1.00 101.39 ? 94  THR H C   1 
ATOM 999  O O   . THR B 2 94  ? 152.544 138.348 197.215 1.00 101.39 ? 94  THR H O   1 
ATOM 1000 C CB  . THR B 2 94  ? 152.274 137.321 199.980 1.00 101.39 ? 94  THR H CB  1 
ATOM 1001 O OG1 . THR B 2 94  ? 152.616 136.449 201.063 1.00 101.39 ? 94  THR H OG1 1 
ATOM 1002 C CG2 . THR B 2 94  ? 150.979 138.051 200.298 1.00 101.39 ? 94  THR H CG2 1 
ATOM 1003 N N   . ALA B 2 95  ? 150.623 137.202 196.919 1.00 85.98  ? 95  ALA H N   1 
ATOM 1004 C CA  . ALA B 2 95  ? 150.276 137.930 195.706 1.00 85.98  ? 95  ALA H CA  1 
ATOM 1005 C C   . ALA B 2 95  ? 148.861 137.554 195.290 1.00 85.98  ? 95  ALA H C   1 
ATOM 1006 O O   . ALA B 2 95  ? 148.246 136.645 195.853 1.00 85.98  ? 95  ALA H O   1 
ATOM 1007 C CB  . ALA B 2 95  ? 151.255 137.631 194.575 1.00 85.98  ? 95  ALA H CB  1 
ATOM 1008 N N   . VAL B 2 96  ? 148.350 138.274 194.300 1.00 78.71  ? 96  VAL H N   1 
ATOM 1009 C CA  . VAL B 2 96  ? 147.081 137.941 193.669 1.00 78.71  ? 96  VAL H CA  1 
ATOM 1010 C C   . VAL B 2 96  ? 147.366 137.084 192.445 1.00 78.71  ? 96  VAL H C   1 
ATOM 1011 O O   . VAL B 2 96  ? 148.208 137.432 191.608 1.00 78.71  ? 96  VAL H O   1 
ATOM 1012 C CB  . VAL B 2 96  ? 146.303 139.208 193.286 1.00 78.71  ? 96  VAL H CB  1 
ATOM 1013 C CG1 . VAL B 2 96  ? 144.880 138.854 192.927 1.00 78.71  ? 96  VAL H CG1 1 
ATOM 1014 C CG2 . VAL B 2 96  ? 146.341 140.218 194.419 1.00 78.71  ? 96  VAL H CG2 1 
ATOM 1015 N N   . TYR B 2 97  ? 146.671 135.958 192.342 1.00 77.81  ? 97  TYR H N   1 
ATOM 1016 C CA  . TYR B 2 97  ? 146.857 135.005 191.264 1.00 77.81  ? 97  TYR H CA  1 
ATOM 1017 C C   . TYR B 2 97  ? 145.674 135.053 190.312 1.00 77.81  ? 97  TYR H C   1 
ATOM 1018 O O   . TYR B 2 97  ? 144.518 135.128 190.742 1.00 77.81  ? 97  TYR H O   1 
ATOM 1019 C CB  . TYR B 2 97  ? 147.031 133.589 191.816 1.00 77.81  ? 97  TYR H CB  1 
ATOM 1020 C CG  . TYR B 2 97  ? 148.338 133.391 192.543 1.00 77.81  ? 97  TYR H CG  1 
ATOM 1021 C CD1 . TYR B 2 97  ? 148.486 133.787 193.861 1.00 77.81  ? 97  TYR H CD1 1 
ATOM 1022 C CD2 . TYR B 2 97  ? 149.427 132.821 191.906 1.00 77.81  ? 97  TYR H CD2 1 
ATOM 1023 C CE1 . TYR B 2 97  ? 149.677 133.615 194.524 1.00 77.81  ? 97  TYR H CE1 1 
ATOM 1024 C CE2 . TYR B 2 97  ? 150.621 132.644 192.563 1.00 77.81  ? 97  TYR H CE2 1 
ATOM 1025 C CZ  . TYR B 2 97  ? 150.741 133.042 193.872 1.00 77.81  ? 97  TYR H CZ  1 
ATOM 1026 O OH  . TYR B 2 97  ? 151.930 132.872 194.537 1.00 77.81  ? 97  TYR H OH  1 
ATOM 1027 N N   . TYR B 2 98  ? 145.977 135.008 189.021 1.00 73.50  ? 98  TYR H N   1 
ATOM 1028 C CA  . TYR B 2 98  ? 144.989 135.080 187.961 1.00 73.50  ? 98  TYR H CA  1 
ATOM 1029 C C   . TYR B 2 98  ? 145.111 133.848 187.081 1.00 73.50  ? 98  TYR H C   1 
ATOM 1030 O O   . TYR B 2 98  ? 146.217 133.386 186.789 1.00 73.50  ? 98  TYR H O   1 
ATOM 1031 C CB  . TYR B 2 98  ? 145.170 136.339 187.101 1.00 73.50  ? 98  TYR H CB  1 
ATOM 1032 C CG  . TYR B 2 98  ? 145.283 137.632 187.873 1.00 73.50  ? 98  TYR H CG  1 
ATOM 1033 C CD1 . TYR B 2 98  ? 146.515 138.090 188.323 1.00 73.50  ? 98  TYR H CD1 1 
ATOM 1034 C CD2 . TYR B 2 98  ? 144.162 138.403 188.137 1.00 73.50  ? 98  TYR H CD2 1 
ATOM 1035 C CE1 . TYR B 2 98  ? 146.624 139.271 189.022 1.00 73.50  ? 98  TYR H CE1 1 
ATOM 1036 C CE2 . TYR B 2 98  ? 144.262 139.587 188.835 1.00 73.50  ? 98  TYR H CE2 1 
ATOM 1037 C CZ  . TYR B 2 98  ? 145.495 140.015 189.274 1.00 73.50  ? 98  TYR H CZ  1 
ATOM 1038 O OH  . TYR B 2 98  ? 145.600 141.193 189.972 1.00 73.50  ? 98  TYR H OH  1 
ATOM 1039 N N   . CYS B 2 99  ? 143.966 133.325 186.669 1.00 73.62  ? 99  CYS H N   1 
ATOM 1040 C CA  . CYS B 2 99  ? 143.883 132.227 185.721 1.00 73.62  ? 99  CYS H CA  1 
ATOM 1041 C C   . CYS B 2 99  ? 143.465 132.801 184.375 1.00 73.62  ? 99  CYS H C   1 
ATOM 1042 O O   . CYS B 2 99  ? 142.498 133.562 184.300 1.00 73.62  ? 99  CYS H O   1 
ATOM 1043 C CB  . CYS B 2 99  ? 142.877 131.186 186.208 1.00 73.62  ? 99  CYS H CB  1 
ATOM 1044 S SG  . CYS B 2 99  ? 142.626 129.739 185.182 1.00 73.62  ? 99  CYS H SG  1 
ATOM 1045 N N   . ALA B 2 100 ? 144.200 132.456 183.324 1.00 61.47  ? 100 ALA H N   1 
ATOM 1046 C CA  . ALA B 2 100 ? 143.994 133.047 182.013 1.00 61.47  ? 100 ALA H CA  1 
ATOM 1047 C C   . ALA B 2 100 ? 143.971 131.968 180.939 1.00 61.47  ? 100 ALA H C   1 
ATOM 1048 O O   . ALA B 2 100 ? 144.614 130.922 181.070 1.00 61.47  ? 100 ALA H O   1 
ATOM 1049 C CB  . ALA B 2 100 ? 145.081 134.083 181.701 1.00 61.47  ? 100 ALA H CB  1 
ATOM 1050 N N   . ARG B 2 101 ? 143.210 132.230 179.882 1.00 65.21  ? 101 ARG H N   1 
ATOM 1051 C CA  . ARG B 2 101 ? 143.122 131.351 178.727 1.00 65.21  ? 101 ARG H CA  1 
ATOM 1052 C C   . ARG B 2 101 ? 144.180 131.714 177.699 1.00 65.21  ? 101 ARG H C   1 
ATOM 1053 O O   . ARG B 2 101 ? 144.681 132.836 177.659 1.00 65.21  ? 101 ARG H O   1 
ATOM 1054 C CB  . ARG B 2 101 ? 141.751 131.442 178.064 1.00 65.21  ? 101 ARG H CB  1 
ATOM 1055 C CG  . ARG B 2 101 ? 140.618 130.950 178.899 1.00 65.21  ? 101 ARG H CG  1 
ATOM 1056 C CD  . ARG B 2 101 ? 139.382 130.800 178.044 1.00 65.21  ? 101 ARG H CD  1 
ATOM 1057 N NE  . ARG B 2 101 ? 138.200 130.528 178.851 1.00 65.21  ? 101 ARG H NE  1 
ATOM 1058 C CZ  . ARG B 2 101 ? 137.948 129.369 179.443 1.00 65.21  ? 101 ARG H CZ  1 
ATOM 1059 N NH1 . ARG B 2 101 ? 138.778 128.346 179.341 1.00 65.21  ? 101 ARG H NH1 1 
ATOM 1060 N NH2 . ARG B 2 101 ? 136.830 129.234 180.146 1.00 65.21  ? 101 ARG H NH2 1 
ATOM 1061 N N   . TRP B 2 102 ? 144.516 130.737 176.859 1.00 59.71  ? 102 TRP H N   1 
ATOM 1062 C CA  . TRP B 2 102 ? 145.295 131.008 175.657 1.00 59.71  ? 102 TRP H CA  1 
ATOM 1063 C C   . TRP B 2 102 ? 145.039 129.882 174.668 1.00 59.71  ? 102 TRP H C   1 
ATOM 1064 O O   . TRP B 2 102 ? 145.191 128.708 175.015 1.00 59.71  ? 102 TRP H O   1 
ATOM 1065 C CB  . TRP B 2 102 ? 146.783 131.142 175.992 1.00 59.71  ? 102 TRP H CB  1 
ATOM 1066 C CG  . TRP B 2 102 ? 147.635 131.651 174.880 1.00 59.71  ? 102 TRP H CG  1 
ATOM 1067 C CD1 . TRP B 2 102 ? 147.254 131.919 173.600 1.00 59.71  ? 102 TRP H CD1 1 
ATOM 1068 C CD2 . TRP B 2 102 ? 149.025 131.949 174.954 1.00 59.71  ? 102 TRP H CD2 1 
ATOM 1069 N NE1 . TRP B 2 102 ? 148.327 132.358 172.872 1.00 59.71  ? 102 TRP H NE1 1 
ATOM 1070 C CE2 . TRP B 2 102 ? 149.429 132.384 173.682 1.00 59.71  ? 102 TRP H CE2 1 
ATOM 1071 C CE3 . TRP B 2 102 ? 149.969 131.887 175.974 1.00 59.71  ? 102 TRP H CE3 1 
ATOM 1072 C CZ2 . TRP B 2 102 ? 150.735 132.757 173.408 1.00 59.71  ? 102 TRP H CZ2 1 
ATOM 1073 C CZ3 . TRP B 2 102 ? 151.258 132.244 175.699 1.00 59.71  ? 102 TRP H CZ3 1 
ATOM 1074 C CH2 . TRP B 2 102 ? 151.634 132.677 174.430 1.00 59.71  ? 102 TRP H CH2 1 
ATOM 1075 N N   . GLY B 2 103 ? 144.647 130.236 173.451 1.00 64.82  ? 103 GLY H N   1 
ATOM 1076 C CA  . GLY B 2 103 ? 144.247 129.251 172.469 1.00 64.82  ? 103 GLY H CA  1 
ATOM 1077 C C   . GLY B 2 103 ? 145.429 128.507 171.893 1.00 64.82  ? 103 GLY H C   1 
ATOM 1078 O O   . GLY B 2 103 ? 146.585 128.722 172.253 1.00 64.82  ? 103 GLY H O   1 
ATOM 1079 N N   . TYR B 2 104 ? 145.122 127.604 170.967 1.00 70.28  ? 104 TYR H N   1 
ATOM 1080 C CA  . TYR B 2 104 ? 146.123 126.749 170.351 1.00 70.28  ? 104 TYR H CA  1 
ATOM 1081 C C   . TYR B 2 104 ? 146.379 127.165 168.911 1.00 70.28  ? 104 TYR H C   1 
ATOM 1082 O O   . TYR B 2 104 ? 145.478 127.621 168.203 1.00 70.28  ? 104 TYR H O   1 
ATOM 1083 C CB  . TYR B 2 104 ? 145.701 125.279 170.382 1.00 70.28  ? 104 TYR H CB  1 
ATOM 1084 C CG  . TYR B 2 104 ? 145.737 124.660 171.753 1.00 70.28  ? 104 TYR H CG  1 
ATOM 1085 C CD1 . TYR B 2 104 ? 146.931 124.513 172.440 1.00 70.28  ? 104 TYR H CD1 1 
ATOM 1086 C CD2 . TYR B 2 104 ? 144.579 124.206 172.352 1.00 70.28  ? 104 TYR H CD2 1 
ATOM 1087 C CE1 . TYR B 2 104 ? 146.965 123.944 173.690 1.00 70.28  ? 104 TYR H CE1 1 
ATOM 1088 C CE2 . TYR B 2 104 ? 144.600 123.640 173.598 1.00 70.28  ? 104 TYR H CE2 1 
ATOM 1089 C CZ  . TYR B 2 104 ? 145.796 123.509 174.264 1.00 70.28  ? 104 TYR H CZ  1 
ATOM 1090 O OH  . TYR B 2 104 ? 145.809 122.938 175.515 1.00 70.28  ? 104 TYR H OH  1 
ATOM 1091 N N   . TRP B 2 105 ? 147.625 126.997 168.490 1.00 67.26  ? 105 TRP H N   1 
ATOM 1092 C CA  . TRP B 2 105 ? 147.993 127.234 167.109 1.00 67.26  ? 105 TRP H CA  1 
ATOM 1093 C C   . TRP B 2 105 ? 147.314 126.205 166.206 1.00 67.26  ? 105 TRP H C   1 
ATOM 1094 O O   . TRP B 2 105 ? 147.149 125.050 166.597 1.00 67.26  ? 105 TRP H O   1 
ATOM 1095 C CB  . TRP B 2 105 ? 149.505 127.137 166.953 1.00 67.26  ? 105 TRP H CB  1 
ATOM 1096 C CG  . TRP B 2 105 ? 149.962 127.495 165.599 1.00 67.26  ? 105 TRP H CG  1 
ATOM 1097 C CD1 . TRP B 2 105 ? 150.141 126.656 164.544 1.00 67.26  ? 105 TRP H CD1 1 
ATOM 1098 C CD2 . TRP B 2 105 ? 150.273 128.806 165.129 1.00 67.26  ? 105 TRP H CD2 1 
ATOM 1099 N NE1 . TRP B 2 105 ? 150.560 127.361 163.446 1.00 67.26  ? 105 TRP H NE1 1 
ATOM 1100 C CE2 . TRP B 2 105 ? 150.649 128.686 163.781 1.00 67.26  ? 105 TRP H CE2 1 
ATOM 1101 C CE3 . TRP B 2 105 ? 150.279 130.070 165.721 1.00 67.26  ? 105 TRP H CE3 1 
ATOM 1102 C CZ2 . TRP B 2 105 ? 151.027 129.782 163.017 1.00 67.26  ? 105 TRP H CZ2 1 
ATOM 1103 C CZ3 . TRP B 2 105 ? 150.651 131.148 164.965 1.00 67.26  ? 105 TRP H CZ3 1 
ATOM 1104 C CH2 . TRP B 2 105 ? 151.017 131.003 163.628 1.00 67.26  ? 105 TRP H CH2 1 
ATOM 1105 N N   . PRO B 2 106 ? 146.910 126.590 164.980 1.00 70.40  ? 106 PRO H N   1 
ATOM 1106 C CA  . PRO B 2 106 ? 146.925 127.911 164.332 1.00 70.40  ? 106 PRO H CA  1 
ATOM 1107 C C   . PRO B 2 106 ? 145.628 128.709 164.459 1.00 70.40  ? 106 PRO H C   1 
ATOM 1108 O O   . PRO B 2 106 ? 144.644 128.232 165.017 1.00 70.40  ? 106 PRO H O   1 
ATOM 1109 C CB  . PRO B 2 106 ? 147.180 127.543 162.870 1.00 70.40  ? 106 PRO H CB  1 
ATOM 1110 C CG  . PRO B 2 106 ? 146.369 126.290 162.708 1.00 70.40  ? 106 PRO H CG  1 
ATOM 1111 C CD  . PRO B 2 106 ? 146.536 125.541 164.013 1.00 70.40  ? 106 PRO H CD  1 
ATOM 1112 N N   . GLY B 2 107 ? 145.607 129.928 163.930 1.00 67.79  ? 107 GLY H N   1 
ATOM 1113 C CA  . GLY B 2 107 ? 144.405 130.736 163.858 1.00 67.79  ? 107 GLY H CA  1 
ATOM 1114 C C   . GLY B 2 107 ? 144.443 131.914 164.819 1.00 67.79  ? 107 GLY H C   1 
ATOM 1115 O O   . GLY B 2 107 ? 145.414 132.148 165.538 1.00 67.79  ? 107 GLY H O   1 
ATOM 1116 N N   . GLU B 2 108 ? 143.347 132.667 164.798 1.00 67.12  ? 108 GLU H N   1 
ATOM 1117 C CA  . GLU B 2 108 ? 143.186 133.766 165.745 1.00 67.12  ? 108 GLU H CA  1 
ATOM 1118 C C   . GLU B 2 108 ? 143.273 133.347 167.210 1.00 67.12  ? 108 GLU H C   1 
ATOM 1119 O O   . GLU B 2 108 ? 143.841 134.122 168.004 1.00 67.12  ? 108 GLU H O   1 
ATOM 1120 C CB  . GLU B 2 108 ? 141.864 134.496 165.481 1.00 67.12  ? 108 GLU H CB  1 
ATOM 1121 C CG  . GLU B 2 108 ? 141.942 135.537 164.381 1.00 67.12  ? 108 GLU H CG  1 
ATOM 1122 C CD  . GLU B 2 108 ? 140.711 136.419 164.330 1.00 67.12  ? 108 GLU H CD  1 
ATOM 1123 O OE1 . GLU B 2 108 ? 139.758 136.159 165.094 1.00 67.12  ? 108 GLU H OE1 1 
ATOM 1124 O OE2 . GLU B 2 108 ? 140.697 137.376 163.528 1.00 67.12  ? 108 GLU H OE2 1 
ATOM 1125 N N   . PRO B 2 109 ? 142.729 132.198 167.643 1.00 60.94  ? 109 PRO H N   1 
ATOM 1126 C CA  . PRO B 2 109 ? 142.811 131.854 169.071 1.00 60.94  ? 109 PRO H CA  1 
ATOM 1127 C C   . PRO B 2 109 ? 144.210 131.886 169.647 1.00 60.94  ? 109 PRO H C   1 
ATOM 1128 O O   . PRO B 2 109 ? 144.365 132.134 170.849 1.00 60.94  ? 109 PRO H O   1 
ATOM 1129 C CB  . PRO B 2 109 ? 142.218 130.444 169.113 1.00 60.94  ? 109 PRO H CB  1 
ATOM 1130 C CG  . PRO B 2 109 ? 141.218 130.456 168.034 1.00 60.94  ? 109 PRO H CG  1 
ATOM 1131 C CD  . PRO B 2 109 ? 141.824 131.275 166.932 1.00 60.94  ? 109 PRO H CD  1 
ATOM 1132 N N   . TRP B 2 110 ? 145.241 131.645 168.849 1.00 56.75  ? 110 TRP H N   1 
ATOM 1133 C CA  . TRP B 2 110 ? 146.578 131.787 169.405 1.00 56.75  ? 110 TRP H CA  1 
ATOM 1134 C C   . TRP B 2 110 ? 146.998 133.247 169.514 1.00 56.75  ? 110 TRP H C   1 
ATOM 1135 O O   . TRP B 2 110 ? 147.700 133.618 170.458 1.00 56.75  ? 110 TRP H O   1 
ATOM 1136 C CB  . TRP B 2 110 ? 147.596 131.015 168.575 1.00 56.75  ? 110 TRP H CB  1 
ATOM 1137 C CG  . TRP B 2 110 ? 148.919 130.939 169.252 1.00 56.75  ? 110 TRP H CG  1 
ATOM 1138 C CD1 . TRP B 2 110 ? 149.330 129.986 170.126 1.00 56.75  ? 110 TRP H CD1 1 
ATOM 1139 C CD2 . TRP B 2 110 ? 150.000 131.864 169.128 1.00 56.75  ? 110 TRP H CD2 1 
ATOM 1140 N NE1 . TRP B 2 110 ? 150.606 130.252 170.551 1.00 56.75  ? 110 TRP H NE1 1 
ATOM 1141 C CE2 . TRP B 2 110 ? 151.040 131.402 169.950 1.00 56.75  ? 110 TRP H CE2 1 
ATOM 1142 C CE3 . TRP B 2 110 ? 150.192 133.036 168.395 1.00 56.75  ? 110 TRP H CE3 1 
ATOM 1143 C CZ2 . TRP B 2 110 ? 152.253 132.070 170.063 1.00 56.75  ? 110 TRP H CZ2 1 
ATOM 1144 C CZ3 . TRP B 2 110 ? 151.396 133.699 168.509 1.00 56.75  ? 110 TRP H CZ3 1 
ATOM 1145 C CH2 . TRP B 2 110 ? 152.411 133.215 169.333 1.00 56.75  ? 110 TRP H CH2 1 
ATOM 1146 N N   . TRP B 2 111 ? 146.594 134.086 168.560 1.00 60.28  ? 111 TRP H N   1 
ATOM 1147 C CA  . TRP B 2 111 ? 147.031 135.478 168.580 1.00 60.28  ? 111 TRP H CA  1 
ATOM 1148 C C   . TRP B 2 111 ? 146.375 136.268 169.706 1.00 60.28  ? 111 TRP H C   1 
ATOM 1149 O O   . TRP B 2 111 ? 147.003 137.168 170.270 1.00 60.28  ? 111 TRP H O   1 
ATOM 1150 C CB  . TRP B 2 111 ? 146.756 136.130 167.225 1.00 60.28  ? 111 TRP H CB  1 
ATOM 1151 C CG  . TRP B 2 111 ? 147.630 135.594 166.139 1.00 60.28  ? 111 TRP H CG  1 
ATOM 1152 C CD1 . TRP B 2 111 ? 147.275 134.720 165.158 1.00 60.28  ? 111 TRP H CD1 1 
ATOM 1153 C CD2 . TRP B 2 111 ? 149.017 135.882 165.936 1.00 60.28  ? 111 TRP H CD2 1 
ATOM 1154 N NE1 . TRP B 2 111 ? 148.353 134.451 164.351 1.00 60.28  ? 111 TRP H NE1 1 
ATOM 1155 C CE2 . TRP B 2 111 ? 149.435 135.152 164.810 1.00 60.28  ? 111 TRP H CE2 1 
ATOM 1156 C CE3 . TRP B 2 111 ? 149.945 136.689 166.598 1.00 60.28  ? 111 TRP H CE3 1 
ATOM 1157 C CZ2 . TRP B 2 111 ? 150.736 135.206 164.333 1.00 60.28  ? 111 TRP H CZ2 1 
ATOM 1158 C CZ3 . TRP B 2 111 ? 151.236 136.741 166.121 1.00 60.28  ? 111 TRP H CZ3 1 
ATOM 1159 C CH2 . TRP B 2 111 ? 151.620 136.006 165.000 1.00 60.28  ? 111 TRP H CH2 1 
ATOM 1160 N N   . LYS B 2 112 ? 145.127 135.941 170.054 1.00 63.78  ? 112 LYS H N   1 
ATOM 1161 C CA  . LYS B 2 112 ? 144.418 136.628 171.137 1.00 63.78  ? 112 LYS H CA  1 
ATOM 1162 C C   . LYS B 2 112 ? 144.874 136.069 172.486 1.00 63.78  ? 112 LYS H C   1 
ATOM 1163 O O   . LYS B 2 112 ? 144.142 135.379 173.198 1.00 63.78  ? 112 LYS H O   1 
ATOM 1164 C CB  . LYS B 2 112 ? 142.915 136.476 170.970 1.00 63.78  ? 112 LYS H CB  1 
ATOM 1165 C CG  . LYS B 2 112 ? 142.378 136.878 169.622 1.00 63.78  ? 112 LYS H CG  1 
ATOM 1166 C CD  . LYS B 2 112 ? 140.872 136.741 169.603 1.00 63.78  ? 112 LYS H CD  1 
ATOM 1167 C CE  . LYS B 2 112 ? 140.299 137.136 168.266 1.00 63.78  ? 112 LYS H CE  1 
ATOM 1168 N NZ  . LYS B 2 112 ? 138.818 137.034 168.286 1.00 63.78  ? 112 LYS H NZ  1 
ATOM 1169 N N   . ALA B 2 113 ? 146.116 136.383 172.835 1.00 57.78  ? 113 ALA H N   1 
ATOM 1170 C CA  . ALA B 2 113 ? 146.684 135.886 174.079 1.00 57.78  ? 113 ALA H CA  1 
ATOM 1171 C C   . ALA B 2 113 ? 145.976 136.501 175.279 1.00 57.78  ? 113 ALA H C   1 
ATOM 1172 O O   . ALA B 2 113 ? 145.771 137.718 175.335 1.00 57.78  ? 113 ALA H O   1 
ATOM 1173 C CB  . ALA B 2 113 ? 148.177 136.192 174.140 1.00 57.78  ? 113 ALA H CB  1 
ATOM 1174 N N   . PHE B 2 114 ? 145.615 135.653 176.244 1.00 59.61  ? 114 PHE H N   1 
ATOM 1175 C CA  . PHE B 2 114 ? 145.021 136.089 177.509 1.00 59.61  ? 114 PHE H CA  1 
ATOM 1176 C C   . PHE B 2 114 ? 143.776 136.943 177.282 1.00 59.61  ? 114 PHE H C   1 
ATOM 1177 O O   . PHE B 2 114 ? 143.626 138.015 177.861 1.00 59.61  ? 114 PHE H O   1 
ATOM 1178 C CB  . PHE B 2 114 ? 146.036 136.853 178.363 1.00 59.61  ? 114 PHE H CB  1 
ATOM 1179 C CG  . PHE B 2 114 ? 147.215 136.036 178.805 1.00 59.61  ? 114 PHE H CG  1 
ATOM 1180 C CD1 . PHE B 2 114 ? 147.151 134.653 178.860 1.00 59.61  ? 114 PHE H CD1 1 
ATOM 1181 C CD2 . PHE B 2 114 ? 148.391 136.658 179.176 1.00 59.61  ? 114 PHE H CD2 1 
ATOM 1182 C CE1 . PHE B 2 114 ? 148.241 133.918 179.273 1.00 59.61  ? 114 PHE H CE1 1 
ATOM 1183 C CE2 . PHE B 2 114 ? 149.481 135.929 179.588 1.00 59.61  ? 114 PHE H CE2 1 
ATOM 1184 C CZ  . PHE B 2 114 ? 149.408 134.558 179.638 1.00 59.61  ? 114 PHE H CZ  1 
ATOM 1185 N N   . ASP B 2 115 ? 142.883 136.469 176.414 1.00 69.59  ? 115 ASP H N   1 
ATOM 1186 C CA  . ASP B 2 115 ? 141.646 137.208 176.170 1.00 69.59  ? 115 ASP H CA  1 
ATOM 1187 C C   . ASP B 2 115 ? 140.837 137.373 177.455 1.00 69.59  ? 115 ASP H C   1 
ATOM 1188 O O   . ASP B 2 115 ? 140.288 138.450 177.717 1.00 69.59  ? 115 ASP H O   1 
ATOM 1189 C CB  . ASP B 2 115 ? 140.819 136.521 175.075 1.00 69.59  ? 115 ASP H CB  1 
ATOM 1190 C CG  . ASP B 2 115 ? 140.473 135.074 175.392 1.00 69.59  ? 115 ASP H CG  1 
ATOM 1191 O OD1 . ASP B 2 115 ? 141.106 134.460 176.273 1.00 69.59  ? 115 ASP H OD1 1 
ATOM 1192 O OD2 . ASP B 2 115 ? 139.567 134.532 174.725 1.00 69.59  ? 115 ASP H OD2 1 
ATOM 1193 N N   . TYR B 2 116 ? 140.768 136.329 178.272 1.00 73.11  ? 116 TYR H N   1 
ATOM 1194 C CA  . TYR B 2 116 ? 140.046 136.351 179.534 1.00 73.11  ? 116 TYR H CA  1 
ATOM 1195 C C   . TYR B 2 116 ? 141.023 136.095 180.671 1.00 73.11  ? 116 TYR H C   1 
ATOM 1196 O O   . TYR B 2 116 ? 141.805 135.142 180.615 1.00 73.11  ? 116 TYR H O   1 
ATOM 1197 C CB  . TYR B 2 116 ? 138.927 135.307 179.533 1.00 73.11  ? 116 TYR H CB  1 
ATOM 1198 C CG  . TYR B 2 116 ? 137.727 135.713 178.711 1.00 73.11  ? 116 TYR H CG  1 
ATOM 1199 C CD1 . TYR B 2 116 ? 137.790 135.761 177.328 1.00 73.11  ? 116 TYR H CD1 1 
ATOM 1200 C CD2 . TYR B 2 116 ? 136.529 136.046 179.321 1.00 73.11  ? 116 TYR H CD2 1 
ATOM 1201 C CE1 . TYR B 2 116 ? 136.692 136.131 176.575 1.00 73.11  ? 116 TYR H CE1 1 
ATOM 1202 C CE2 . TYR B 2 116 ? 135.426 136.421 178.578 1.00 73.11  ? 116 TYR H CE2 1 
ATOM 1203 C CZ  . TYR B 2 116 ? 135.513 136.461 177.206 1.00 73.11  ? 116 TYR H CZ  1 
ATOM 1204 O OH  . TYR B 2 116 ? 134.415 136.831 176.464 1.00 73.11  ? 116 TYR H OH  1 
ATOM 1205 N N   . TRP B 2 117 ? 140.999 136.959 181.689 1.00 59.75  ? 117 TRP H N   1 
ATOM 1206 C CA  . TRP B 2 117 ? 141.796 136.756 182.893 1.00 59.75  ? 117 TRP H CA  1 
ATOM 1207 C C   . TRP B 2 117 ? 140.970 136.316 184.091 1.00 59.75  ? 117 TRP H C   1 
ATOM 1208 O O   . TRP B 2 117 ? 141.543 136.062 185.156 1.00 59.75  ? 117 TRP H O   1 
ATOM 1209 C CB  . TRP B 2 117 ? 142.560 138.028 183.270 1.00 59.75  ? 117 TRP H CB  1 
ATOM 1210 C CG  . TRP B 2 117 ? 143.700 138.376 182.387 1.00 59.75  ? 117 TRP H CG  1 
ATOM 1211 C CD1 . TRP B 2 117 ? 143.631 138.811 181.105 1.00 59.75  ? 117 TRP H CD1 1 
ATOM 1212 C CD2 . TRP B 2 117 ? 145.087 138.370 182.736 1.00 59.75  ? 117 TRP H CD2 1 
ATOM 1213 N NE1 . TRP B 2 117 ? 144.887 139.059 180.621 1.00 59.75  ? 117 TRP H NE1 1 
ATOM 1214 C CE2 . TRP B 2 117 ? 145.802 138.798 181.605 1.00 59.75  ? 117 TRP H CE2 1 
ATOM 1215 C CE3 . TRP B 2 117 ? 145.795 138.041 183.893 1.00 59.75  ? 117 TRP H CE3 1 
ATOM 1216 C CZ2 . TRP B 2 117 ? 147.187 138.901 181.592 1.00 59.75  ? 117 TRP H CZ2 1 
ATOM 1217 C CZ3 . TRP B 2 117 ? 147.170 138.140 183.879 1.00 59.75  ? 117 TRP H CZ3 1 
ATOM 1218 C CH2 . TRP B 2 117 ? 147.852 138.566 182.736 1.00 59.75  ? 117 TRP H CH2 1 
ATOM 1219 N N   . GLY B 2 118 ? 139.653 136.208 183.953 1.00 72.06  ? 118 GLY H N   1 
ATOM 1220 C CA  . GLY B 2 118 ? 138.830 135.910 185.114 1.00 72.06  ? 118 GLY H CA  1 
ATOM 1221 C C   . GLY B 2 118 ? 138.952 136.995 186.169 1.00 72.06  ? 118 GLY H C   1 
ATOM 1222 O O   . GLY B 2 118 ? 138.814 138.190 185.884 1.00 72.06  ? 118 GLY H O   1 
ATOM 1223 N N   . GLN B 2 119 ? 139.218 136.580 187.407 1.00 87.04  ? 119 GLN H N   1 
ATOM 1224 C CA  . GLN B 2 119 ? 139.379 137.488 188.535 1.00 87.04  ? 119 GLN H CA  1 
ATOM 1225 C C   . GLN B 2 119 ? 140.628 137.100 189.308 1.00 87.04  ? 119 GLN H C   1 
ATOM 1226 O O   . GLN B 2 119 ? 141.209 136.033 189.097 1.00 87.04  ? 119 GLN H O   1 
ATOM 1227 C CB  . GLN B 2 119 ? 138.161 137.462 189.468 1.00 87.04  ? 119 GLN H CB  1 
ATOM 1228 C CG  . GLN B 2 119 ? 138.073 136.204 190.315 1.00 87.04  ? 119 GLN H CG  1 
ATOM 1229 C CD  . GLN B 2 119 ? 136.747 136.068 191.030 1.00 87.04  ? 119 GLN H CD  1 
ATOM 1230 O OE1 . GLN B 2 119 ? 135.832 136.864 190.822 1.00 87.04  ? 119 GLN H OE1 1 
ATOM 1231 N NE2 . GLN B 2 119 ? 136.634 135.053 191.879 1.00 87.04  ? 119 GLN H NE2 1 
ATOM 1232 N N   . GLY B 2 120 ? 141.062 137.981 190.199 1.00 87.80  ? 120 GLY H N   1 
ATOM 1233 C CA  . GLY B 2 120 ? 142.190 137.681 191.054 1.00 87.80  ? 120 GLY H CA  1 
ATOM 1234 C C   . GLY B 2 120 ? 141.775 136.960 192.326 1.00 87.80  ? 120 GLY H C   1 
ATOM 1235 O O   . GLY B 2 120 ? 140.688 137.177 192.861 1.00 87.80  ? 120 GLY H O   1 
ATOM 1236 N N   . THR B 2 121 ? 142.652 136.081 192.807 1.00 93.36  ? 121 THR H N   1 
ATOM 1237 C CA  . THR B 2 121 ? 142.494 135.443 194.107 1.00 93.36  ? 121 THR H CA  1 
ATOM 1238 C C   . THR B 2 121 ? 143.744 135.705 194.936 1.00 93.36  ? 121 THR H C   1 
ATOM 1239 O O   . THR B 2 121 ? 144.858 135.445 194.480 1.00 93.36  ? 121 THR H O   1 
ATOM 1240 C CB  . THR B 2 121 ? 142.241 133.939 193.961 1.00 93.36  ? 121 THR H CB  1 
ATOM 1241 O OG1 . THR B 2 121 ? 140.866 133.718 193.624 1.00 93.36  ? 121 THR H OG1 1 
ATOM 1242 C CG2 . THR B 2 121 ? 142.561 133.213 195.251 1.00 93.36  ? 121 THR H CG2 1 
ATOM 1243 N N   . LEU B 2 122 ? 143.562 136.224 196.146 1.00 95.85  ? 122 LEU H N   1 
ATOM 1244 C CA  . LEU B 2 122 ? 144.681 136.658 196.971 1.00 95.85  ? 122 LEU H CA  1 
ATOM 1245 C C   . LEU B 2 122 ? 145.219 135.496 197.795 1.00 95.85  ? 122 LEU H C   1 
ATOM 1246 O O   . LEU B 2 122 ? 144.460 134.820 198.494 1.00 95.85  ? 122 LEU H O   1 
ATOM 1247 C CB  . LEU B 2 122 ? 144.250 137.803 197.889 1.00 95.85  ? 122 LEU H CB  1 
ATOM 1248 C CG  . LEU B 2 122 ? 145.285 138.362 198.862 1.00 95.85  ? 122 LEU H CG  1 
ATOM 1249 C CD1 . LEU B 2 122 ? 146.483 138.913 198.116 1.00 95.85  ? 122 LEU H CD1 1 
ATOM 1250 C CD2 . LEU B 2 122 ? 144.645 139.435 199.720 1.00 95.85  ? 122 LEU H CD2 1 
ATOM 1251 N N   . VAL B 2 123 ? 146.527 135.267 197.711 1.00 101.06 ? 123 VAL H N   1 
ATOM 1252 C CA  . VAL B 2 123 ? 147.226 134.302 198.549 1.00 101.06 ? 123 VAL H CA  1 
ATOM 1253 C C   . VAL B 2 123 ? 148.171 135.082 199.449 1.00 101.06 ? 123 VAL H C   1 
ATOM 1254 O O   . VAL B 2 123 ? 149.038 135.820 198.964 1.00 101.06 ? 123 VAL H O   1 
ATOM 1255 C CB  . VAL B 2 123 ? 147.989 133.261 197.713 1.00 101.06 ? 123 VAL H CB  1 
ATOM 1256 C CG1 . VAL B 2 123 ? 149.030 132.549 198.564 1.00 101.06 ? 123 VAL H CG1 1 
ATOM 1257 C CG2 . VAL B 2 123 ? 147.021 132.263 197.107 1.00 101.06 ? 123 VAL H CG2 1 
ATOM 1258 N N   . THR B 2 124 ? 147.996 134.925 200.757 1.00 112.08 ? 124 THR H N   1 
ATOM 1259 C CA  . THR B 2 124 ? 148.812 135.594 201.756 1.00 112.08 ? 124 THR H CA  1 
ATOM 1260 C C   . THR B 2 124 ? 149.626 134.544 202.492 1.00 112.08 ? 124 THR H C   1 
ATOM 1261 O O   . THR B 2 124 ? 149.078 133.534 202.940 1.00 112.08 ? 124 THR H O   1 
ATOM 1262 C CB  . THR B 2 124 ? 147.942 136.388 202.735 1.00 112.08 ? 124 THR H CB  1 
ATOM 1263 O OG1 . THR B 2 124 ? 147.017 137.201 202.004 1.00 112.08 ? 124 THR H OG1 1 
ATOM 1264 C CG2 . THR B 2 124 ? 148.802 137.283 203.604 1.00 112.08 ? 124 THR H CG2 1 
ATOM 1265 N N   . VAL B 2 125 ? 150.933 134.764 202.581 1.00 115.18 ? 125 VAL H N   1 
ATOM 1266 C CA  . VAL B 2 125 ? 151.852 133.841 203.230 1.00 115.18 ? 125 VAL H CA  1 
ATOM 1267 C C   . VAL B 2 125 ? 152.554 134.603 204.342 1.00 115.18 ? 125 VAL H C   1 
ATOM 1268 O O   . VAL B 2 125 ? 153.414 135.450 204.073 1.00 115.18 ? 125 VAL H O   1 
ATOM 1269 C CB  . VAL B 2 125 ? 152.868 133.247 202.244 1.00 115.18 ? 125 VAL H CB  1 
ATOM 1270 C CG1 . VAL B 2 125 ? 153.674 132.147 202.913 1.00 115.18 ? 125 VAL H CG1 1 
ATOM 1271 C CG2 . VAL B 2 125 ? 152.163 132.726 201.001 1.00 115.18 ? 125 VAL H CG2 1 
ATOM 1272 N N   . SER B 2 126 ? 152.201 134.301 205.589 1.00 120.97 ? 126 SER H N   1 
ATOM 1273 C CA  . SER B 2 126 ? 152.824 134.965 206.724 1.00 120.97 ? 126 SER H CA  1 
ATOM 1274 C C   . SER B 2 126 ? 152.545 134.174 207.992 1.00 120.97 ? 126 SER H C   1 
ATOM 1275 O O   . SER B 2 126 ? 151.469 133.594 208.156 1.00 120.97 ? 126 SER H O   1 
ATOM 1276 C CB  . SER B 2 126 ? 152.322 136.403 206.884 1.00 120.97 ? 126 SER H CB  1 
ATOM 1277 O OG  . SER B 2 126 ? 152.886 137.011 208.032 1.00 120.97 ? 126 SER H OG  1 
ATOM 1278 N N   . SER B 2 127 ? 153.523 134.180 208.894 1.00 126.13 ? 127 SER H N   1 
ATOM 1279 C CA  . SER B 2 127 ? 153.394 133.499 210.173 1.00 126.13 ? 127 SER H CA  1 
ATOM 1280 C C   . SER B 2 127 ? 152.643 134.319 211.213 1.00 126.13 ? 127 SER H C   1 
ATOM 1281 O O   . SER B 2 127 ? 152.349 133.794 212.293 1.00 126.13 ? 127 SER H O   1 
ATOM 1282 C CB  . SER B 2 127 ? 154.782 133.141 210.710 1.00 126.13 ? 127 SER H CB  1 
ATOM 1283 O OG  . SER B 2 127 ? 155.625 134.280 210.727 1.00 126.13 ? 127 SER H OG  1 
ATOM 1284 N N   . ALA B 2 128 ? 152.331 135.579 210.921 1.00 132.20 ? 128 ALA H N   1 
ATOM 1285 C CA  . ALA B 2 128 ? 151.676 136.441 211.894 1.00 132.20 ? 128 ALA H CA  1 
ATOM 1286 C C   . ALA B 2 128 ? 150.275 135.937 212.218 1.00 132.20 ? 128 ALA H C   1 
ATOM 1287 O O   . ALA B 2 128 ? 149.542 135.473 211.340 1.00 132.20 ? 128 ALA H O   1 
ATOM 1288 C CB  . ALA B 2 128 ? 151.609 137.875 211.370 1.00 132.20 ? 128 ALA H CB  1 
ATOM 1289 N N   . SER B 2 129 ? 149.905 136.034 213.490 1.00 138.34 ? 129 SER H N   1 
ATOM 1290 C CA  . SER B 2 129 ? 148.599 135.594 213.951 1.00 138.34 ? 129 SER H CA  1 
ATOM 1291 C C   . SER B 2 129 ? 147.593 136.742 213.925 1.00 138.34 ? 129 SER H C   1 
ATOM 1292 O O   . SER B 2 129 ? 147.954 137.921 213.912 1.00 138.34 ? 129 SER H O   1 
ATOM 1293 C CB  . SER B 2 129 ? 148.698 135.015 215.363 1.00 138.34 ? 129 SER H CB  1 
ATOM 1294 O OG  . SER B 2 129 ? 149.356 135.917 216.238 1.00 138.34 ? 129 SER H OG  1 
ATOM 1295 N N   . THR B 2 130 ? 146.313 136.376 213.922 1.00 140.09 ? 130 THR H N   1 
ATOM 1296 C CA  . THR B 2 130 ? 145.242 137.362 213.872 1.00 140.09 ? 130 THR H CA  1 
ATOM 1297 C C   . THR B 2 130 ? 145.236 138.197 215.148 1.00 140.09 ? 130 THR H C   1 
ATOM 1298 O O   . THR B 2 130 ? 145.265 137.658 216.257 1.00 140.09 ? 130 THR H O   1 
ATOM 1299 C CB  . THR B 2 130 ? 143.898 136.665 213.671 1.00 140.09 ? 130 THR H CB  1 
ATOM 1300 O OG1 . THR B 2 130 ? 143.897 135.989 212.406 1.00 140.09 ? 130 THR H OG1 1 
ATOM 1301 C CG2 . THR B 2 130 ? 142.753 137.662 213.705 1.00 140.09 ? 130 THR H CG2 1 
ATOM 1302 N N   . LYS B 2 131 ? 145.198 139.518 214.989 1.00 139.97 ? 131 LYS H N   1 
ATOM 1303 C CA  . LYS B 2 131 ? 145.416 140.427 216.104 1.00 139.97 ? 131 LYS H CA  1 
ATOM 1304 C C   . LYS B 2 131 ? 144.666 141.726 215.863 1.00 139.97 ? 131 LYS H C   1 
ATOM 1305 O O   . LYS B 2 131 ? 144.664 142.247 214.746 1.00 139.97 ? 131 LYS H O   1 
ATOM 1306 C CB  . LYS B 2 131 ? 146.910 140.712 216.283 1.00 139.97 ? 131 LYS H CB  1 
ATOM 1307 C CG  . LYS B 2 131 ? 147.220 141.726 217.360 1.00 139.97 ? 131 LYS H CG  1 
ATOM 1308 C CD  . LYS B 2 131 ? 148.695 142.073 217.376 1.00 139.97 ? 131 LYS H CD  1 
ATOM 1309 C CE  . LYS B 2 131 ? 149.023 142.993 218.538 1.00 139.97 ? 131 LYS H CE  1 
ATOM 1310 N NZ  . LYS B 2 131 ? 148.121 144.178 218.576 1.00 139.97 ? 131 LYS H NZ  1 
ATOM 1311 N N   . GLY B 2 132 ? 144.036 142.246 216.915 1.00 142.38 ? 132 GLY H N   1 
ATOM 1312 C CA  . GLY B 2 132 ? 143.362 143.519 216.843 1.00 142.38 ? 132 GLY H CA  1 
ATOM 1313 C C   . GLY B 2 132 ? 144.320 144.691 216.938 1.00 142.38 ? 132 GLY H C   1 
ATOM 1314 O O   . GLY B 2 132 ? 145.352 144.632 217.613 1.00 142.38 ? 132 GLY H O   1 
ATOM 1315 N N   . PRO B 2 133 ? 143.991 145.784 216.258 1.00 140.93 ? 133 PRO H N   1 
ATOM 1316 C CA  . PRO B 2 133 ? 144.855 146.965 216.286 1.00 140.93 ? 133 PRO H CA  1 
ATOM 1317 C C   . PRO B 2 133 ? 144.653 147.806 217.536 1.00 140.93 ? 133 PRO H C   1 
ATOM 1318 O O   . PRO B 2 133 ? 143.625 147.746 218.214 1.00 140.93 ? 133 PRO H O   1 
ATOM 1319 C CB  . PRO B 2 133 ? 144.422 147.741 215.041 1.00 140.93 ? 133 PRO H CB  1 
ATOM 1320 C CG  . PRO B 2 133 ? 142.993 147.373 214.869 1.00 140.93 ? 133 PRO H CG  1 
ATOM 1321 C CD  . PRO B 2 133 ? 142.854 145.952 215.338 1.00 140.93 ? 133 PRO H CD  1 
ATOM 1322 N N   . SER B 2 134 ? 145.671 148.608 217.825 1.00 137.23 ? 134 SER H N   1 
ATOM 1323 C CA  . SER B 2 134 ? 145.585 149.639 218.847 1.00 137.23 ? 134 SER H CA  1 
ATOM 1324 C C   . SER B 2 134 ? 145.550 151.005 218.175 1.00 137.23 ? 134 SER H C   1 
ATOM 1325 O O   . SER B 2 134 ? 146.255 151.243 217.184 1.00 137.23 ? 134 SER H O   1 
ATOM 1326 C CB  . SER B 2 134 ? 146.758 149.549 219.821 1.00 137.23 ? 134 SER H CB  1 
ATOM 1327 O OG  . SER B 2 134 ? 146.721 148.345 220.567 1.00 137.23 ? 134 SER H OG  1 
ATOM 1328 N N   . VAL B 2 135 ? 144.732 151.899 218.714 1.00 135.88 ? 135 VAL H N   1 
ATOM 1329 C CA  . VAL B 2 135 ? 144.427 153.175 218.080 1.00 135.88 ? 135 VAL H CA  1 
ATOM 1330 C C   . VAL B 2 135 ? 145.032 154.287 218.915 1.00 135.88 ? 135 VAL H C   1 
ATOM 1331 O O   . VAL B 2 135 ? 144.814 154.352 220.129 1.00 135.88 ? 135 VAL H O   1 
ATOM 1332 C CB  . VAL B 2 135 ? 142.913 153.374 217.917 1.00 135.88 ? 135 VAL H CB  1 
ATOM 1333 C CG1 . VAL B 2 135 ? 142.628 154.727 217.300 1.00 135.88 ? 135 VAL H CG1 1 
ATOM 1334 C CG2 . VAL B 2 135 ? 142.330 152.266 217.068 1.00 135.88 ? 135 VAL H CG2 1 
ATOM 1335 N N   . PHE B 2 136 ? 145.791 155.158 218.260 1.00 133.37 ? 136 PHE H N   1 
ATOM 1336 C CA  . PHE B 2 136 ? 146.518 156.237 218.922 1.00 133.37 ? 136 PHE H CA  1 
ATOM 1337 C C   . PHE B 2 136 ? 146.297 157.528 218.151 1.00 133.37 ? 136 PHE H C   1 
ATOM 1338 O O   . PHE B 2 136 ? 147.020 157.821 217.187 1.00 133.37 ? 136 PHE H O   1 
ATOM 1339 C CB  . PHE B 2 136 ? 148.000 155.902 219.036 1.00 133.37 ? 136 PHE H CB  1 
ATOM 1340 C CG  . PHE B 2 136 ? 148.260 154.559 219.632 1.00 133.37 ? 136 PHE H CG  1 
ATOM 1341 C CD1 . PHE B 2 136 ? 147.873 154.282 220.932 1.00 133.37 ? 136 PHE H CD1 1 
ATOM 1342 C CD2 . PHE B 2 136 ? 148.885 153.570 218.895 1.00 133.37 ? 136 PHE H CD2 1 
ATOM 1343 C CE1 . PHE B 2 136 ? 148.106 153.046 221.486 1.00 133.37 ? 136 PHE H CE1 1 
ATOM 1344 C CE2 . PHE B 2 136 ? 149.125 152.333 219.442 1.00 133.37 ? 136 PHE H CE2 1 
ATOM 1345 C CZ  . PHE B 2 136 ? 148.737 152.072 220.742 1.00 133.37 ? 136 PHE H CZ  1 
ATOM 1346 N N   . PRO B 2 137 ? 145.291 158.314 218.527 1.00 132.05 ? 137 PRO H N   1 
ATOM 1347 C CA  . PRO B 2 137 ? 145.138 159.639 217.919 1.00 132.05 ? 137 PRO H CA  1 
ATOM 1348 C C   . PRO B 2 137 ? 146.374 160.485 218.158 1.00 132.05 ? 137 PRO H C   1 
ATOM 1349 O O   . PRO B 2 137 ? 146.971 160.459 219.235 1.00 132.05 ? 137 PRO H O   1 
ATOM 1350 C CB  . PRO B 2 137 ? 143.916 160.225 218.634 1.00 132.05 ? 137 PRO H CB  1 
ATOM 1351 C CG  . PRO B 2 137 ? 143.222 159.077 219.214 1.00 132.05 ? 137 PRO H CG  1 
ATOM 1352 C CD  . PRO B 2 137 ? 144.261 158.057 219.543 1.00 132.05 ? 137 PRO H CD  1 
ATOM 1353 N N   . LEU B 2 138 ? 146.750 161.240 217.142 1.00 130.83 ? 138 LEU H N   1 
ATOM 1354 C CA  . LEU B 2 138 ? 147.908 162.119 217.197 1.00 130.83 ? 138 LEU H CA  1 
ATOM 1355 C C   . LEU B 2 138 ? 147.381 163.546 217.128 1.00 130.83 ? 138 LEU H C   1 
ATOM 1356 O O   . LEU B 2 138 ? 147.277 164.129 216.051 1.00 130.83 ? 138 LEU H O   1 
ATOM 1357 C CB  . LEU B 2 138 ? 148.858 161.820 216.067 1.00 130.83 ? 138 LEU H CB  1 
ATOM 1358 C CG  . LEU B 2 138 ? 149.140 160.344 215.819 1.00 130.83 ? 138 LEU H CG  1 
ATOM 1359 C CD1 . LEU B 2 138 ? 149.985 160.232 214.585 1.00 130.83 ? 138 LEU H CD1 1 
ATOM 1360 C CD2 . LEU B 2 138 ? 149.842 159.722 217.015 1.00 130.83 ? 138 LEU H CD2 1 
ATOM 1361 N N   . ALA B 2 139 ? 147.055 164.102 218.287 1.00 141.87 ? 139 ALA H N   1 
ATOM 1362 C CA  . ALA B 2 139 ? 146.469 165.429 218.339 1.00 141.87 ? 139 ALA H CA  1 
ATOM 1363 C C   . ALA B 2 139 ? 147.475 166.482 217.879 1.00 141.87 ? 139 ALA H C   1 
ATOM 1364 O O   . ALA B 2 139 ? 148.674 166.367 218.161 1.00 141.87 ? 139 ALA H O   1 
ATOM 1365 C CB  . ALA B 2 139 ? 145.995 165.740 219.752 1.00 141.87 ? 139 ALA H CB  1 
ATOM 1366 N N   . PRO B 2 140 ? 147.023 167.512 217.170 1.00 147.71 ? 140 PRO H N   1 
ATOM 1367 C CA  . PRO B 2 140 ? 147.947 168.554 216.719 1.00 147.71 ? 140 PRO H CA  1 
ATOM 1368 C C   . PRO B 2 140 ? 148.494 169.361 217.883 1.00 147.71 ? 140 PRO H C   1 
ATOM 1369 O O   . PRO B 2 140 ? 147.825 169.570 218.898 1.00 147.71 ? 140 PRO H O   1 
ATOM 1370 C CB  . PRO B 2 140 ? 147.079 169.422 215.802 1.00 147.71 ? 140 PRO H CB  1 
ATOM 1371 C CG  . PRO B 2 140 ? 145.701 169.224 216.310 1.00 147.71 ? 140 PRO H CG  1 
ATOM 1372 C CD  . PRO B 2 140 ? 145.634 167.795 216.769 1.00 147.71 ? 140 PRO H CD  1 
ATOM 1373 N N   . SER B 2 141 ? 149.731 169.818 217.726 1.00 156.77 ? 141 SER H N   1 
ATOM 1374 C CA  . SER B 2 141 ? 150.328 170.657 218.748 1.00 156.77 ? 141 SER H CA  1 
ATOM 1375 C C   . SER B 2 141 ? 149.831 172.093 218.603 1.00 156.77 ? 141 SER H C   1 
ATOM 1376 O O   . SER B 2 141 ? 149.141 172.449 217.643 1.00 156.77 ? 141 SER H O   1 
ATOM 1377 C CB  . SER B 2 141 ? 151.854 170.607 218.667 1.00 156.77 ? 141 SER H CB  1 
ATOM 1378 O OG  . SER B 2 141 ? 152.339 171.448 217.635 1.00 156.77 ? 141 SER H OG  1 
ATOM 1379 N N   . SER B 2 142 ? 150.187 172.927 219.581 1.00 160.47 ? 142 SER H N   1 
ATOM 1380 C CA  . SER B 2 142 ? 149.810 174.335 219.527 1.00 160.47 ? 142 SER H CA  1 
ATOM 1381 C C   . SER B 2 142 ? 150.437 175.049 218.338 1.00 160.47 ? 142 SER H C   1 
ATOM 1382 O O   . SER B 2 142 ? 149.965 176.124 217.955 1.00 160.47 ? 142 SER H O   1 
ATOM 1383 C CB  . SER B 2 142 ? 150.208 175.033 220.827 1.00 160.47 ? 142 SER H CB  1 
ATOM 1384 O OG  . SER B 2 142 ? 151.591 174.864 221.086 1.00 160.47 ? 142 SER H OG  1 
ATOM 1385 N N   . LYS B 2 143 ? 151.479 174.468 217.742 1.00 163.57 ? 143 LYS H N   1 
ATOM 1386 C CA  . LYS B 2 143 ? 152.160 175.048 216.592 1.00 163.57 ? 143 LYS H CA  1 
ATOM 1387 C C   . LYS B 2 143 ? 152.028 174.203 215.330 1.00 163.57 ? 143 LYS H C   1 
ATOM 1388 O O   . LYS B 2 143 ? 152.705 174.493 214.337 1.00 163.57 ? 143 LYS H O   1 
ATOM 1389 C CB  . LYS B 2 143 ? 153.641 175.257 216.914 1.00 163.57 ? 143 LYS H CB  1 
ATOM 1390 C CG  . LYS B 2 143 ? 153.882 176.119 218.134 1.00 163.57 ? 143 LYS H CG  1 
ATOM 1391 C CD  . LYS B 2 143 ? 153.371 177.524 217.898 1.00 163.57 ? 143 LYS H CD  1 
ATOM 1392 C CE  . LYS B 2 143 ? 153.649 178.420 219.088 1.00 163.57 ? 143 LYS H CE  1 
ATOM 1393 N NZ  . LYS B 2 143 ? 153.261 179.826 218.798 1.00 163.57 ? 143 LYS H NZ  1 
ATOM 1394 N N   . SER B 2 144 ? 151.195 173.160 215.342 1.00 160.26 ? 144 SER H N   1 
ATOM 1395 C CA  . SER B 2 144 ? 151.000 172.303 214.170 1.00 160.26 ? 144 SER H CA  1 
ATOM 1396 C C   . SER B 2 144 ? 149.965 172.943 213.238 1.00 160.26 ? 144 SER H C   1 
ATOM 1397 O O   . SER B 2 144 ? 148.812 172.521 213.143 1.00 160.26 ? 144 SER H O   1 
ATOM 1398 C CB  . SER B 2 144 ? 150.588 170.900 214.596 1.00 160.26 ? 144 SER H CB  1 
ATOM 1399 O OG  . SER B 2 144 ? 151.645 170.235 215.267 1.00 160.26 ? 144 SER H OG  1 
ATOM 1400 N N   . THR B 2 145 ? 150.415 174.003 212.558 1.00 163.20 ? 145 THR H N   1 
ATOM 1401 C CA  . THR B 2 145 ? 149.658 174.810 211.592 1.00 163.20 ? 145 THR H CA  1 
ATOM 1402 C C   . THR B 2 145 ? 148.469 175.525 212.215 1.00 163.20 ? 145 THR H C   1 
ATOM 1403 O O   . THR B 2 145 ? 147.567 175.952 211.491 1.00 163.20 ? 145 THR H O   1 
ATOM 1404 C CB  . THR B 2 145 ? 149.160 174.002 210.379 1.00 163.20 ? 145 THR H CB  1 
ATOM 1405 O OG1 . THR B 2 145 ? 147.999 173.244 210.742 1.00 163.20 ? 145 THR H OG1 1 
ATOM 1406 C CG2 . THR B 2 145 ? 150.245 173.074 209.851 1.00 163.20 ? 145 THR H CG2 1 
ATOM 1407 N N   . SER B 2 146 ? 148.440 175.653 213.545 1.00 162.04 ? 146 SER H N   1 
ATOM 1408 C CA  . SER B 2 146 ? 147.350 176.355 214.213 1.00 162.04 ? 146 SER H CA  1 
ATOM 1409 C C   . SER B 2 146 ? 147.225 177.784 213.694 1.00 162.04 ? 146 SER H C   1 
ATOM 1410 O O   . SER B 2 146 ? 148.223 178.465 213.442 1.00 162.04 ? 146 SER H O   1 
ATOM 1411 C CB  . SER B 2 146 ? 147.577 176.362 215.726 1.00 162.04 ? 146 SER H CB  1 
ATOM 1412 O OG  . SER B 2 146 ? 146.519 177.026 216.394 1.00 162.04 ? 146 SER H OG  1 
ATOM 1413 N N   . GLY B 2 147 ? 145.980 178.229 213.524 1.00 160.76 ? 147 GLY H N   1 
ATOM 1414 C CA  . GLY B 2 147 ? 145.660 179.531 212.980 1.00 160.76 ? 147 GLY H CA  1 
ATOM 1415 C C   . GLY B 2 147 ? 145.013 179.493 211.611 1.00 160.76 ? 147 GLY H C   1 
ATOM 1416 O O   . GLY B 2 147 ? 144.319 180.450 211.242 1.00 160.76 ? 147 GLY H O   1 
ATOM 1417 N N   . GLY B 2 148 ? 145.210 178.418 210.852 1.00 156.73 ? 148 GLY H N   1 
ATOM 1418 C CA  . GLY B 2 148 ? 144.588 178.278 209.550 1.00 156.73 ? 148 GLY H CA  1 
ATOM 1419 C C   . GLY B 2 148 ? 143.609 177.124 209.512 1.00 156.73 ? 148 GLY H C   1 
ATOM 1420 O O   . GLY B 2 148 ? 142.530 177.193 210.107 1.00 156.73 ? 148 GLY H O   1 
ATOM 1421 N N   . THR B 2 149 ? 143.970 176.067 208.794 1.00 147.06 ? 149 THR H N   1 
ATOM 1422 C CA  . THR B 2 149 ? 143.278 174.788 208.845 1.00 147.06 ? 149 THR H CA  1 
ATOM 1423 C C   . THR B 2 149 ? 144.281 173.733 209.286 1.00 147.06 ? 149 THR H C   1 
ATOM 1424 O O   . THR B 2 149 ? 145.442 173.763 208.866 1.00 147.06 ? 149 THR H O   1 
ATOM 1425 C CB  . THR B 2 149 ? 142.668 174.424 207.482 1.00 147.06 ? 149 THR H CB  1 
ATOM 1426 O OG1 . THR B 2 149 ? 141.788 175.472 207.055 1.00 147.06 ? 149 THR H OG1 1 
ATOM 1427 C CG2 . THR B 2 149 ? 141.879 173.130 207.566 1.00 147.06 ? 149 THR H CG2 1 
ATOM 1428 N N   . ALA B 2 150 ? 143.849 172.813 210.148 1.00 138.01 ? 150 ALA H N   1 
ATOM 1429 C CA  . ALA B 2 150 ? 144.765 171.860 210.759 1.00 138.01 ? 150 ALA H CA  1 
ATOM 1430 C C   . ALA B 2 150 ? 144.230 170.443 210.627 1.00 138.01 ? 150 ALA H C   1 
ATOM 1431 O O   . ALA B 2 150 ? 143.016 170.215 210.675 1.00 138.01 ? 150 ALA H O   1 
ATOM 1432 C CB  . ALA B 2 150 ? 145.014 172.190 212.237 1.00 138.01 ? 150 ALA H CB  1 
ATOM 1433 N N   . ALA B 2 151 ? 145.147 169.499 210.446 1.00 127.40 ? 151 ALA H N   1 
ATOM 1434 C CA  . ALA B 2 151 ? 144.802 168.089 210.386 1.00 127.40 ? 151 ALA H CA  1 
ATOM 1435 C C   . ALA B 2 151 ? 144.650 167.501 211.786 1.00 127.40 ? 151 ALA H C   1 
ATOM 1436 O O   . ALA B 2 151 ? 145.260 167.969 212.752 1.00 127.40 ? 151 ALA H O   1 
ATOM 1437 C CB  . ALA B 2 151 ? 145.866 167.314 209.611 1.00 127.40 ? 151 ALA H CB  1 
ATOM 1438 N N   . LEU B 2 152 ? 143.837 166.451 211.887 1.00 129.40 ? 152 LEU H N   1 
ATOM 1439 C CA  . LEU B 2 152 ? 143.552 165.841 213.182 1.00 129.40 ? 152 LEU H CA  1 
ATOM 1440 C C   . LEU B 2 152 ? 144.594 164.798 213.577 1.00 129.40 ? 152 LEU H C   1 
ATOM 1441 O O   . LEU B 2 152 ? 145.207 164.909 214.639 1.00 129.40 ? 152 LEU H O   1 
ATOM 1442 C CB  . LEU B 2 152 ? 142.159 165.216 213.175 1.00 129.40 ? 152 LEU H CB  1 
ATOM 1443 C CG  . LEU B 2 152 ? 141.001 166.205 213.149 1.00 129.40 ? 152 LEU H CG  1 
ATOM 1444 C CD1 . LEU B 2 152 ? 139.699 165.482 213.342 1.00 129.40 ? 152 LEU H CD1 1 
ATOM 1445 C CD2 . LEU B 2 152 ? 141.196 167.237 214.226 1.00 129.40 ? 152 LEU H CD2 1 
ATOM 1446 N N   . GLY B 2 153 ? 144.797 163.779 212.739 1.00 128.97 ? 153 GLY H N   1 
ATOM 1447 C CA  . GLY B 2 153 ? 145.738 162.713 213.051 1.00 128.97 ? 153 GLY H CA  1 
ATOM 1448 C C   . GLY B 2 153 ? 145.154 161.509 213.774 1.00 128.97 ? 153 GLY H C   1 
ATOM 1449 O O   . GLY B 2 153 ? 144.366 161.666 214.712 1.00 128.97 ? 153 GLY H O   1 
ATOM 1450 N N   . CYS B 2 154 ? 145.537 160.301 213.349 1.00 130.56 ? 154 CYS H N   1 
ATOM 1451 C CA  . CYS B 2 154 ? 145.083 159.074 214.001 1.00 130.56 ? 154 CYS H CA  1 
ATOM 1452 C C   . CYS B 2 154 ? 145.891 157.869 213.512 1.00 130.56 ? 154 CYS H C   1 
ATOM 1453 O O   . CYS B 2 154 ? 146.130 157.726 212.315 1.00 130.56 ? 154 CYS H O   1 
ATOM 1454 C CB  . CYS B 2 154 ? 143.593 158.839 213.737 1.00 130.56 ? 154 CYS H CB  1 
ATOM 1455 S SG  . CYS B 2 154 ? 142.936 157.322 214.437 1.00 130.56 ? 154 CYS H SG  1 
ATOM 1456 N N   . LEU B 2 155 ? 146.287 157.003 214.443 1.00 128.23 ? 155 LEU H N   1 
ATOM 1457 C CA  . LEU B 2 155 ? 147.107 155.840 214.114 1.00 128.23 ? 155 LEU H CA  1 
ATOM 1458 C C   . LEU B 2 155 ? 146.355 154.548 214.387 1.00 128.23 ? 155 LEU H C   1 
ATOM 1459 O O   . LEU B 2 155 ? 145.748 154.391 215.452 1.00 128.23 ? 155 LEU H O   1 
ATOM 1460 C CB  . LEU B 2 155 ? 148.409 155.841 214.908 1.00 128.23 ? 155 LEU H CB  1 
ATOM 1461 C CG  . LEU B 2 155 ? 149.600 156.505 214.231 1.00 128.23 ? 155 LEU H CG  1 
ATOM 1462 C CD1 . LEU B 2 155 ? 150.818 156.386 215.109 1.00 128.23 ? 155 LEU H CD1 1 
ATOM 1463 C CD2 . LEU B 2 155 ? 149.852 155.875 212.877 1.00 128.23 ? 155 LEU H CD2 1 
ATOM 1464 N N   . VAL B 2 156 ? 146.418 153.620 213.440 1.00 127.48 ? 156 VAL H N   1 
ATOM 1465 C CA  . VAL B 2 156 ? 145.980 152.249 213.609 1.00 127.48 ? 156 VAL H CA  1 
ATOM 1466 C C   . VAL B 2 156 ? 147.224 151.387 213.494 1.00 127.48 ? 156 VAL H C   1 
ATOM 1467 O O   . VAL B 2 156 ? 147.901 151.406 212.465 1.00 127.48 ? 156 VAL H O   1 
ATOM 1468 C CB  . VAL B 2 156 ? 144.940 151.858 212.551 1.00 127.48 ? 156 VAL H CB  1 
ATOM 1469 C CG1 . VAL B 2 156 ? 144.327 150.520 212.884 1.00 127.48 ? 156 VAL H CG1 1 
ATOM 1470 C CG2 . VAL B 2 156 ? 143.878 152.933 212.434 1.00 127.48 ? 156 VAL H CG2 1 
ATOM 1471 N N   . LYS B 2 157 ? 147.551 150.648 214.549 1.00 131.19 ? 157 LYS H N   1 
ATOM 1472 C CA  . LYS B 2 157 ? 148.842 149.981 214.597 1.00 131.19 ? 157 LYS H CA  1 
ATOM 1473 C C   . LYS B 2 157 ? 148.690 148.508 214.956 1.00 131.19 ? 157 LYS H C   1 
ATOM 1474 O O   . LYS B 2 157 ? 147.872 148.147 215.817 1.00 131.19 ? 157 LYS H O   1 
ATOM 1475 C CB  . LYS B 2 157 ? 149.767 150.674 215.602 1.00 131.19 ? 157 LYS H CB  1 
ATOM 1476 C CG  . LYS B 2 157 ? 151.234 150.382 215.388 1.00 131.19 ? 157 LYS H CG  1 
ATOM 1477 C CD  . LYS B 2 157 ? 152.094 151.173 216.354 1.00 131.19 ? 157 LYS H CD  1 
ATOM 1478 C CE  . LYS B 2 157 ? 153.570 150.872 216.162 1.00 131.19 ? 157 LYS H CE  1 
ATOM 1479 N NZ  . LYS B 2 157 ? 153.894 149.471 216.538 1.00 131.19 ? 157 LYS H NZ  1 
ATOM 1480 N N   . ASP B 2 158 ? 149.495 147.665 214.291 1.00 134.12 ? 158 ASP H N   1 
ATOM 1481 C CA  . ASP B 2 158 ? 149.700 146.265 214.655 1.00 134.12 ? 158 ASP H CA  1 
ATOM 1482 C C   . ASP B 2 158 ? 148.395 145.463 214.596 1.00 134.12 ? 158 ASP H C   1 
ATOM 1483 O O   . ASP B 2 158 ? 147.871 145.003 215.610 1.00 134.12 ? 158 ASP H O   1 
ATOM 1484 C CB  . ASP B 2 158 ? 150.347 146.149 216.036 1.00 134.12 ? 158 ASP H CB  1 
ATOM 1485 C CG  . ASP B 2 158 ? 151.639 146.926 216.142 1.00 134.12 ? 158 ASP H CG  1 
ATOM 1486 O OD1 . ASP B 2 158 ? 152.261 147.202 215.097 1.00 134.12 ? 158 ASP H OD1 1 
ATOM 1487 O OD2 . ASP B 2 158 ? 152.037 147.254 217.278 1.00 134.12 ? 158 ASP H OD2 1 
ATOM 1488 N N   . TYR B 2 159 ? 147.875 145.304 213.380 1.00 135.72 ? 159 TYR H N   1 
ATOM 1489 C CA  . TYR B 2 159 ? 146.722 144.440 213.157 1.00 135.72 ? 159 TYR H CA  1 
ATOM 1490 C C   . TYR B 2 159 ? 147.023 143.430 212.057 1.00 135.72 ? 159 TYR H C   1 
ATOM 1491 O O   . TYR B 2 159 ? 147.898 143.642 211.215 1.00 135.72 ? 159 TYR H O   1 
ATOM 1492 C CB  . TYR B 2 159 ? 145.470 145.236 212.790 1.00 135.72 ? 159 TYR H CB  1 
ATOM 1493 C CG  . TYR B 2 159 ? 145.653 146.139 211.597 1.00 135.72 ? 159 TYR H CG  1 
ATOM 1494 C CD1 . TYR B 2 159 ? 146.152 147.423 211.748 1.00 135.72 ? 159 TYR H CD1 1 
ATOM 1495 C CD2 . TYR B 2 159 ? 145.330 145.709 210.319 1.00 135.72 ? 159 TYR H CD2 1 
ATOM 1496 C CE1 . TYR B 2 159 ? 146.322 148.252 210.666 1.00 135.72 ? 159 TYR H CE1 1 
ATOM 1497 C CE2 . TYR B 2 159 ? 145.493 146.538 209.228 1.00 135.72 ? 159 TYR H CE2 1 
ATOM 1498 C CZ  . TYR B 2 159 ? 145.990 147.807 209.413 1.00 135.72 ? 159 TYR H CZ  1 
ATOM 1499 O OH  . TYR B 2 159 ? 146.159 148.641 208.341 1.00 135.72 ? 159 TYR H OH  1 
ATOM 1500 N N   . PHE B 2 160 ? 146.283 142.318 212.068 1.00 136.30 ? 160 PHE H N   1 
ATOM 1501 C CA  . PHE B 2 160 ? 146.462 141.303 211.035 1.00 136.30 ? 160 PHE H CA  1 
ATOM 1502 C C   . PHE B 2 160 ? 145.239 140.397 210.957 1.00 136.30 ? 160 PHE H C   1 
ATOM 1503 O O   . PHE B 2 160 ? 144.733 139.948 211.991 1.00 136.30 ? 160 PHE H O   1 
ATOM 1504 C CB  . PHE B 2 160 ? 147.723 140.479 211.299 1.00 136.30 ? 160 PHE H CB  1 
ATOM 1505 C CG  . PHE B 2 160 ? 148.136 139.613 210.142 1.00 136.30 ? 160 PHE H CG  1 
ATOM 1506 C CD1 . PHE B 2 160 ? 147.564 138.365 209.957 1.00 136.30 ? 160 PHE H CD1 1 
ATOM 1507 C CD2 . PHE B 2 160 ? 149.098 140.044 209.242 1.00 136.30 ? 160 PHE H CD2 1 
ATOM 1508 C CE1 . PHE B 2 160 ? 147.936 137.567 208.899 1.00 136.30 ? 160 PHE H CE1 1 
ATOM 1509 C CE2 . PHE B 2 160 ? 149.476 139.246 208.179 1.00 136.30 ? 160 PHE H CE2 1 
ATOM 1510 C CZ  . PHE B 2 160 ? 148.893 138.005 208.009 1.00 136.30 ? 160 PHE H CZ  1 
ATOM 1511 N N   . PRO B 2 161 ? 144.724 140.114 209.755 1.00 137.59 ? 161 PRO H N   1 
ATOM 1512 C CA  . PRO B 2 161 ? 145.140 140.625 208.439 1.00 137.59 ? 161 PRO H CA  1 
ATOM 1513 C C   . PRO B 2 161 ? 144.705 142.077 208.225 1.00 137.59 ? 161 PRO H C   1 
ATOM 1514 O O   . PRO B 2 161 ? 144.480 142.798 209.191 1.00 137.59 ? 161 PRO H O   1 
ATOM 1515 C CB  . PRO B 2 161 ? 144.452 139.659 207.467 1.00 137.59 ? 161 PRO H CB  1 
ATOM 1516 C CG  . PRO B 2 161 ? 143.207 139.248 208.193 1.00 137.59 ? 161 PRO H CG  1 
ATOM 1517 C CD  . PRO B 2 161 ? 143.636 139.127 209.632 1.00 137.59 ? 161 PRO H CD  1 
ATOM 1518 N N   . GLU B 2 162 ? 144.574 142.558 206.991 1.00 135.42 ? 162 GLU H N   1 
ATOM 1519 C CA  . GLU B 2 162 ? 144.354 143.988 206.829 1.00 135.42 ? 162 GLU H CA  1 
ATOM 1520 C C   . GLU B 2 162 ? 143.061 144.382 206.116 1.00 135.42 ? 162 GLU H C   1 
ATOM 1521 O O   . GLU B 2 162 ? 143.107 145.202 205.189 1.00 135.42 ? 162 GLU H O   1 
ATOM 1522 C CB  . GLU B 2 162 ? 145.536 144.591 206.074 1.00 135.42 ? 162 GLU H CB  1 
ATOM 1523 C CG  . GLU B 2 162 ? 145.897 143.820 204.818 1.00 135.42 ? 162 GLU H CG  1 
ATOM 1524 C CD  . GLU B 2 162 ? 146.803 144.599 203.890 1.00 135.42 ? 162 GLU H CD  1 
ATOM 1525 O OE1 . GLU B 2 162 ? 147.339 145.640 204.319 1.00 135.42 ? 162 GLU H OE1 1 
ATOM 1526 O OE2 . GLU B 2 162 ? 146.976 144.174 202.727 1.00 135.42 ? 162 GLU H OE2 1 
ATOM 1527 N N   . PRO B 2 163 ? 141.890 143.845 206.492 1.00 137.08 ? 163 PRO H N   1 
ATOM 1528 C CA  . PRO B 2 163 ? 140.651 144.560 206.105 1.00 137.08 ? 163 PRO H CA  1 
ATOM 1529 C C   . PRO B 2 163 ? 140.162 145.506 207.200 1.00 137.08 ? 163 PRO H C   1 
ATOM 1530 O O   . PRO B 2 163 ? 139.171 145.255 207.896 1.00 137.08 ? 163 PRO H O   1 
ATOM 1531 C CB  . PRO B 2 163 ? 139.684 143.408 205.834 1.00 137.08 ? 163 PRO H CB  1 
ATOM 1532 C CG  . PRO B 2 163 ? 140.101 142.359 206.796 1.00 137.08 ? 163 PRO H CG  1 
ATOM 1533 C CD  . PRO B 2 163 ? 141.593 142.478 206.960 1.00 137.08 ? 163 PRO H CD  1 
ATOM 1534 N N   . VAL B 2 164 ? 140.859 146.628 207.372 1.00 135.81 ? 164 VAL H N   1 
ATOM 1535 C CA  . VAL B 2 164 ? 140.572 147.585 208.440 1.00 135.81 ? 164 VAL H CA  1 
ATOM 1536 C C   . VAL B 2 164 ? 139.800 148.762 207.867 1.00 135.81 ? 164 VAL H C   1 
ATOM 1537 O O   . VAL B 2 164 ? 140.190 149.329 206.839 1.00 135.81 ? 164 VAL H O   1 
ATOM 1538 C CB  . VAL B 2 164 ? 141.865 148.065 209.123 1.00 135.81 ? 164 VAL H CB  1 
ATOM 1539 C CG1 . VAL B 2 164 ? 141.686 149.466 209.677 1.00 135.81 ? 164 VAL H CG1 1 
ATOM 1540 C CG2 . VAL B 2 164 ? 142.236 147.125 210.235 1.00 135.81 ? 164 VAL H CG2 1 
ATOM 1541 N N   . THR B 2 165 ? 138.712 149.139 208.535 1.00 139.88 ? 165 THR H N   1 
ATOM 1542 C CA  . THR B 2 165 ? 137.890 150.271 208.130 1.00 139.88 ? 165 THR H CA  1 
ATOM 1543 C C   . THR B 2 165 ? 138.015 151.393 209.153 1.00 139.88 ? 165 THR H C   1 
ATOM 1544 O O   . THR B 2 165 ? 137.782 151.181 210.347 1.00 139.88 ? 165 THR H O   1 
ATOM 1545 C CB  . THR B 2 165 ? 136.426 149.855 207.973 1.00 139.88 ? 165 THR H CB  1 
ATOM 1546 O OG1 . THR B 2 165 ? 136.318 148.883 206.926 1.00 139.88 ? 165 THR H OG1 1 
ATOM 1547 C CG2 . THR B 2 165 ? 135.565 151.055 207.622 1.00 139.88 ? 165 THR H CG2 1 
ATOM 1548 N N   . VAL B 2 166 ? 138.365 152.589 208.683 1.00 137.40 ? 166 VAL H N   1 
ATOM 1549 C CA  . VAL B 2 166 ? 138.608 153.743 209.540 1.00 137.40 ? 166 VAL H CA  1 
ATOM 1550 C C   . VAL B 2 166 ? 137.693 154.878 209.106 1.00 137.40 ? 166 VAL H C   1 
ATOM 1551 O O   . VAL B 2 166 ? 137.600 155.183 207.911 1.00 137.40 ? 166 VAL H O   1 
ATOM 1552 C CB  . VAL B 2 166 ? 140.080 154.189 209.492 1.00 137.40 ? 166 VAL H CB  1 
ATOM 1553 C CG1 . VAL B 2 166 ? 140.287 155.403 210.372 1.00 137.40 ? 166 VAL H CG1 1 
ATOM 1554 C CG2 . VAL B 2 166 ? 140.993 153.058 209.925 1.00 137.40 ? 166 VAL H CG2 1 
ATOM 1555 N N   . SER B 2 167 ? 137.026 155.504 210.073 1.00 140.65 ? 167 SER H N   1 
ATOM 1556 C CA  . SER B 2 167 ? 136.160 156.646 209.816 1.00 140.65 ? 167 SER H CA  1 
ATOM 1557 C C   . SER B 2 167 ? 136.324 157.654 210.942 1.00 140.65 ? 167 SER H C   1 
ATOM 1558 O O   . SER B 2 167 ? 136.988 157.392 211.947 1.00 140.65 ? 167 SER H O   1 
ATOM 1559 C CB  . SER B 2 167 ? 134.690 156.232 209.683 1.00 140.65 ? 167 SER H CB  1 
ATOM 1560 O OG  . SER B 2 167 ? 134.224 155.611 210.867 1.00 140.65 ? 167 SER H OG  1 
ATOM 1561 N N   . TRP B 2 168 ? 135.727 158.829 210.761 1.00 139.20 ? 168 TRP H N   1 
ATOM 1562 C CA  . TRP B 2 168 ? 135.744 159.873 211.774 1.00 139.20 ? 168 TRP H CA  1 
ATOM 1563 C C   . TRP B 2 168 ? 134.322 160.279 212.128 1.00 139.20 ? 168 TRP H C   1 
ATOM 1564 O O   . TRP B 2 168 ? 133.474 160.431 211.244 1.00 139.20 ? 168 TRP H O   1 
ATOM 1565 C CB  . TRP B 2 168 ? 136.525 161.095 211.305 1.00 139.20 ? 168 TRP H CB  1 
ATOM 1566 C CG  . TRP B 2 168 ? 137.978 160.835 211.099 1.00 139.20 ? 168 TRP H CG  1 
ATOM 1567 C CD1 . TRP B 2 168 ? 138.554 160.237 210.023 1.00 139.20 ? 168 TRP H CD1 1 
ATOM 1568 C CD2 . TRP B 2 168 ? 139.045 161.184 211.986 1.00 139.20 ? 168 TRP H CD2 1 
ATOM 1569 N NE1 . TRP B 2 168 ? 139.915 160.185 210.184 1.00 139.20 ? 168 TRP H NE1 1 
ATOM 1570 C CE2 . TRP B 2 168 ? 140.243 160.760 211.383 1.00 139.20 ? 168 TRP H CE2 1 
ATOM 1571 C CE3 . TRP B 2 168 ? 139.104 161.810 213.232 1.00 139.20 ? 168 TRP H CE3 1 
ATOM 1572 C CZ2 . TRP B 2 168 ? 141.486 160.944 211.982 1.00 139.20 ? 168 TRP H CZ2 1 
ATOM 1573 C CZ3 . TRP B 2 168 ? 140.339 161.990 213.825 1.00 139.20 ? 168 TRP H CZ3 1 
ATOM 1574 C CH2 . TRP B 2 168 ? 141.512 161.558 213.201 1.00 139.20 ? 168 TRP H CH2 1 
ATOM 1575 N N   . ASN B 2 169 ? 134.076 160.456 213.428 1.00 144.73 ? 169 ASN H N   1 
ATOM 1576 C CA  . ASN B 2 169 ? 132.774 160.886 213.943 1.00 144.73 ? 169 ASN H CA  1 
ATOM 1577 C C   . ASN B 2 169 ? 131.646 160.016 213.398 1.00 144.73 ? 169 ASN H C   1 
ATOM 1578 O O   . ASN B 2 169 ? 130.586 160.507 213.005 1.00 144.73 ? 169 ASN H O   1 
ATOM 1579 C CB  . ASN B 2 169 ? 132.525 162.363 213.643 1.00 144.73 ? 169 ASN H CB  1 
ATOM 1580 C CG  . ASN B 2 169 ? 133.518 163.268 214.340 1.00 144.73 ? 169 ASN H CG  1 
ATOM 1581 O OD1 . ASN B 2 169 ? 134.222 162.845 215.255 1.00 144.73 ? 169 ASN H OD1 1 
ATOM 1582 N ND2 . ASN B 2 169 ? 133.575 164.523 213.916 1.00 144.73 ? 169 ASN H ND2 1 
ATOM 1583 N N   . SER B 2 170 ? 131.887 158.704 213.380 1.00 145.41 ? 170 SER H N   1 
ATOM 1584 C CA  . SER B 2 170 ? 130.933 157.716 212.879 1.00 145.41 ? 170 SER H CA  1 
ATOM 1585 C C   . SER B 2 170 ? 130.519 158.005 211.439 1.00 145.41 ? 170 SER H C   1 
ATOM 1586 O O   . SER B 2 170 ? 129.379 157.749 211.047 1.00 145.41 ? 170 SER H O   1 
ATOM 1587 C CB  . SER B 2 170 ? 129.701 157.622 213.783 1.00 145.41 ? 170 SER H CB  1 
ATOM 1588 O OG  . SER B 2 170 ? 130.069 157.248 215.100 1.00 145.41 ? 170 SER H OG  1 
ATOM 1589 N N   . GLY B 2 171 ? 131.447 158.534 210.640 1.00 143.13 ? 171 GLY H N   1 
ATOM 1590 C CA  . GLY B 2 171 ? 131.201 158.831 209.246 1.00 143.13 ? 171 GLY H CA  1 
ATOM 1591 C C   . GLY B 2 171 ? 130.723 160.237 208.961 1.00 143.13 ? 171 GLY H C   1 
ATOM 1592 O O   . GLY B 2 171 ? 130.650 160.623 207.786 1.00 143.13 ? 171 GLY H O   1 
ATOM 1593 N N   . ALA B 2 172 ? 130.396 161.018 209.994 1.00 142.39 ? 172 ALA H N   1 
ATOM 1594 C CA  . ALA B 2 172 ? 129.869 162.359 209.772 1.00 142.39 ? 172 ALA H CA  1 
ATOM 1595 C C   . ALA B 2 172 ? 130.902 163.278 209.134 1.00 142.39 ? 172 ALA H C   1 
ATOM 1596 O O   . ALA B 2 172 ? 130.533 164.215 208.417 1.00 142.39 ? 172 ALA H O   1 
ATOM 1597 C CB  . ALA B 2 172 ? 129.372 162.951 211.092 1.00 142.39 ? 172 ALA H CB  1 
ATOM 1598 N N   . LEU B 2 173 ? 132.186 163.032 209.376 1.00 139.12 ? 173 LEU H N   1 
ATOM 1599 C CA  . LEU B 2 173 ? 133.257 163.904 208.898 1.00 139.12 ? 173 LEU H CA  1 
ATOM 1600 C C   . LEU B 2 173 ? 133.772 163.353 207.574 1.00 139.12 ? 173 LEU H C   1 
ATOM 1601 O O   . LEU B 2 173 ? 134.569 162.413 207.545 1.00 139.12 ? 173 LEU H O   1 
ATOM 1602 C CB  . LEU B 2 173 ? 134.367 164.004 209.938 1.00 139.12 ? 173 LEU H CB  1 
ATOM 1603 C CG  . LEU B 2 173 ? 135.183 165.296 210.009 1.00 139.12 ? 173 LEU H CG  1 
ATOM 1604 C CD1 . LEU B 2 173 ? 136.024 165.310 211.269 1.00 139.12 ? 173 LEU H CD1 1 
ATOM 1605 C CD2 . LEU B 2 173 ? 136.067 165.461 208.790 1.00 139.12 ? 173 LEU H CD2 1 
ATOM 1606 N N   . THR B 2 174 ? 133.325 163.952 206.470 1.00 135.04 ? 174 THR H N   1 
ATOM 1607 C CA  . THR B 2 174 ? 133.780 163.576 205.140 1.00 135.04 ? 174 THR H CA  1 
ATOM 1608 C C   . THR B 2 174 ? 134.684 164.616 204.494 1.00 135.04 ? 174 THR H C   1 
ATOM 1609 O O   . THR B 2 174 ? 135.233 164.351 203.419 1.00 135.04 ? 174 THR H O   1 
ATOM 1610 C CB  . THR B 2 174 ? 132.582 163.322 204.216 1.00 135.04 ? 174 THR H CB  1 
ATOM 1611 O OG1 . THR B 2 174 ? 131.793 164.514 204.120 1.00 135.04 ? 174 THR H OG1 1 
ATOM 1612 C CG2 . THR B 2 174 ? 131.723 162.193 204.757 1.00 135.04 ? 174 THR H CG2 1 
ATOM 1613 N N   . SER B 2 175 ? 134.854 165.781 205.112 1.00 128.77 ? 175 SER H N   1 
ATOM 1614 C CA  . SER B 2 175 ? 135.644 166.854 204.525 1.00 128.77 ? 175 SER H CA  1 
ATOM 1615 C C   . SER B 2 175 ? 137.130 166.581 204.730 1.00 128.77 ? 175 SER H C   1 
ATOM 1616 O O   . SER B 2 175 ? 137.600 166.477 205.868 1.00 128.77 ? 175 SER H O   1 
ATOM 1617 C CB  . SER B 2 175 ? 135.254 168.195 205.142 1.00 128.77 ? 175 SER H CB  1 
ATOM 1618 O OG  . SER B 2 175 ? 136.080 169.235 204.651 1.00 128.77 ? 175 SER H OG  1 
ATOM 1619 N N   . GLY B 2 176 ? 137.867 166.468 203.630 1.00 122.87 ? 176 GLY H N   1 
ATOM 1620 C CA  . GLY B 2 176 ? 139.305 166.326 203.716 1.00 122.87 ? 176 GLY H CA  1 
ATOM 1621 C C   . GLY B 2 176 ? 139.789 164.992 204.230 1.00 122.87 ? 176 GLY H C   1 
ATOM 1622 O O   . GLY B 2 176 ? 140.895 164.917 204.773 1.00 122.87 ? 176 GLY H O   1 
ATOM 1623 N N   . VAL B 2 177 ? 138.996 163.931 204.073 1.00 118.08 ? 177 VAL H N   1 
ATOM 1624 C CA  . VAL B 2 177 ? 139.391 162.622 204.580 1.00 118.08 ? 177 VAL H CA  1 
ATOM 1625 C C   . VAL B 2 177 ? 140.475 162.029 203.689 1.00 118.08 ? 177 VAL H C   1 
ATOM 1626 O O   . VAL B 2 177 ? 140.337 161.979 202.460 1.00 118.08 ? 177 VAL H O   1 
ATOM 1627 C CB  . VAL B 2 177 ? 138.176 161.688 204.673 1.00 118.08 ? 177 VAL H CB  1 
ATOM 1628 C CG1 . VAL B 2 177 ? 138.577 160.377 205.322 1.00 118.08 ? 177 VAL H CG1 1 
ATOM 1629 C CG2 . VAL B 2 177 ? 137.068 162.349 205.457 1.00 118.08 ? 177 VAL H CG2 1 
ATOM 1630 N N   . HIS B 2 178 ? 141.566 161.586 204.313 1.00 107.46 ? 178 HIS H N   1 
ATOM 1631 C CA  . HIS B 2 178 ? 142.671 160.905 203.642 1.00 107.46 ? 178 HIS H CA  1 
ATOM 1632 C C   . HIS B 2 178 ? 143.060 159.719 204.519 1.00 107.46 ? 178 HIS H C   1 
ATOM 1633 O O   . HIS B 2 178 ? 143.777 159.877 205.512 1.00 107.46 ? 178 HIS H O   1 
ATOM 1634 C CB  . HIS B 2 178 ? 143.846 161.847 203.420 1.00 107.46 ? 178 HIS H CB  1 
ATOM 1635 C CG  . HIS B 2 178 ? 143.483 163.083 202.662 1.00 107.46 ? 178 HIS H CG  1 
ATOM 1636 N ND1 . HIS B 2 178 ? 143.152 163.065 201.325 1.00 107.46 ? 178 HIS H ND1 1 
ATOM 1637 C CD2 . HIS B 2 178 ? 143.393 164.375 203.055 1.00 107.46 ? 178 HIS H CD2 1 
ATOM 1638 C CE1 . HIS B 2 178 ? 142.877 164.293 200.926 1.00 107.46 ? 178 HIS H CE1 1 
ATOM 1639 N NE2 . HIS B 2 178 ? 143.016 165.107 201.956 1.00 107.46 ? 178 HIS H NE2 1 
ATOM 1640 N N   . THR B 2 179 ? 142.556 158.542 204.173 1.00 107.07 ? 179 THR H N   1 
ATOM 1641 C CA  . THR B 2 179 ? 142.931 157.310 204.851 1.00 107.07 ? 179 THR H CA  1 
ATOM 1642 C C   . THR B 2 179 ? 144.003 156.609 204.029 1.00 107.07 ? 179 THR H C   1 
ATOM 1643 O O   . THR B 2 179 ? 143.798 156.328 202.844 1.00 107.07 ? 179 THR H O   1 
ATOM 1644 C CB  . THR B 2 179 ? 141.721 156.403 205.051 1.00 107.07 ? 179 THR H CB  1 
ATOM 1645 O OG1 . THR B 2 179 ? 140.747 157.075 205.857 1.00 107.07 ? 179 THR H OG1 1 
ATOM 1646 C CG2 . THR B 2 179 ? 142.133 155.116 205.738 1.00 107.07 ? 179 THR H CG2 1 
ATOM 1647 N N   . PHE B 2 180 ? 145.086 156.338 204.630 1.00 99.05  ? 180 PHE H N   1 
ATOM 1648 C CA  . PHE B 2 180 ? 146.188 155.873 203.809 1.00 99.05  ? 180 PHE H CA  1 
ATOM 1649 C C   . PHE B 2 180 ? 146.180 154.353 203.681 1.00 99.05  ? 180 PHE H C   1 
ATOM 1650 O O   . PHE B 2 180 ? 145.729 153.649 204.589 1.00 99.05  ? 180 PHE H O   1 
ATOM 1651 C CB  . PHE B 2 180 ? 147.512 156.341 204.400 1.00 99.05  ? 180 PHE H CB  1 
ATOM 1652 C CG  . PHE B 2 180 ? 147.696 157.824 204.333 1.00 99.05  ? 180 PHE H CG  1 
ATOM 1653 C CD1 . PHE B 2 180 ? 147.161 158.655 205.305 1.00 99.05  ? 180 PHE H CD1 1 
ATOM 1654 C CD2 . PHE B 2 180 ? 148.384 158.394 203.279 1.00 99.05  ? 180 PHE H CD2 1 
ATOM 1655 C CE1 . PHE B 2 180 ? 147.323 160.022 205.226 1.00 99.05  ? 180 PHE H CE1 1 
ATOM 1656 C CE2 . PHE B 2 180 ? 148.547 159.755 203.197 1.00 99.05  ? 180 PHE H CE2 1 
ATOM 1657 C CZ  . PHE B 2 180 ? 148.018 160.571 204.170 1.00 99.05  ? 180 PHE H CZ  1 
ATOM 1658 N N   . PRO B 2 181 ? 146.651 153.832 202.548 1.00 99.47  ? 181 PRO H N   1 
ATOM 1659 C CA  . PRO B 2 181 ? 146.741 152.377 202.392 1.00 99.47  ? 181 PRO H CA  1 
ATOM 1660 C C   . PRO B 2 181 ? 147.644 151.764 203.454 1.00 99.47  ? 181 PRO H C   1 
ATOM 1661 O O   . PRO B 2 181 ? 148.665 152.338 203.837 1.00 99.47  ? 181 PRO H O   1 
ATOM 1662 C CB  . PRO B 2 181 ? 147.325 152.209 200.985 1.00 99.47  ? 181 PRO H CB  1 
ATOM 1663 C CG  . PRO B 2 181 ? 146.961 153.467 200.276 1.00 99.47  ? 181 PRO H CG  1 
ATOM 1664 C CD  . PRO B 2 181 ? 147.022 154.544 201.314 1.00 99.47  ? 181 PRO H CD  1 
ATOM 1665 N N   . ALA B 2 182 ? 147.252 150.588 203.932 1.00 115.53 ? 182 ALA H N   1 
ATOM 1666 C CA  . ALA B 2 182 ? 147.999 149.921 204.985 1.00 115.53 ? 182 ALA H CA  1 
ATOM 1667 C C   . ALA B 2 182 ? 149.383 149.520 204.499 1.00 115.53 ? 182 ALA H C   1 
ATOM 1668 O O   . ALA B 2 182 ? 149.596 149.251 203.315 1.00 115.53 ? 182 ALA H O   1 
ATOM 1669 C CB  . ALA B 2 182 ? 147.248 148.688 205.469 1.00 115.53 ? 182 ALA H CB  1 
ATOM 1670 N N   . VAL B 2 183 ? 150.329 149.480 205.432 1.00 121.29 ? 183 VAL H N   1 
ATOM 1671 C CA  . VAL B 2 183 ? 151.692 149.061 205.130 1.00 121.29 ? 183 VAL H CA  1 
ATOM 1672 C C   . VAL B 2 183 ? 152.061 147.904 206.047 1.00 121.29 ? 183 VAL H C   1 
ATOM 1673 O O   . VAL B 2 183 ? 151.553 147.784 207.172 1.00 121.29 ? 183 VAL H O   1 
ATOM 1674 C CB  . VAL B 2 183 ? 152.696 150.222 205.278 1.00 121.29 ? 183 VAL H CB  1 
ATOM 1675 C CG1 . VAL B 2 183 ? 152.391 151.309 204.269 1.00 121.29 ? 183 VAL H CG1 1 
ATOM 1676 C CG2 . VAL B 2 183 ? 152.660 150.772 206.689 1.00 121.29 ? 183 VAL H CG2 1 
ATOM 1677 N N   . LEU B 2 184 ? 152.944 147.040 205.553 1.00 129.40 ? 184 LEU H N   1 
ATOM 1678 C CA  . LEU B 2 184 ? 153.387 145.875 206.301 1.00 129.40 ? 184 LEU H CA  1 
ATOM 1679 C C   . LEU B 2 184 ? 154.641 146.215 207.094 1.00 129.40 ? 184 LEU H C   1 
ATOM 1680 O O   . LEU B 2 184 ? 155.566 146.845 206.575 1.00 129.40 ? 184 LEU H O   1 
ATOM 1681 C CB  . LEU B 2 184 ? 153.661 144.704 205.354 1.00 129.40 ? 184 LEU H CB  1 
ATOM 1682 C CG  . LEU B 2 184 ? 153.925 143.347 206.005 1.00 129.40 ? 184 LEU H CG  1 
ATOM 1683 C CD1 . LEU B 2 184 ? 152.705 142.875 206.770 1.00 129.40 ? 184 LEU H CD1 1 
ATOM 1684 C CD2 . LEU B 2 184 ? 154.335 142.323 204.964 1.00 129.40 ? 184 LEU H CD2 1 
ATOM 1685 N N   . GLN B 2 185 ? 154.664 145.794 208.355 1.00 136.37 ? 185 GLN H N   1 
ATOM 1686 C CA  . GLN B 2 185 ? 155.782 146.036 209.256 1.00 136.37 ? 185 GLN H CA  1 
ATOM 1687 C C   . GLN B 2 185 ? 156.727 144.844 209.254 1.00 136.37 ? 185 GLN H C   1 
ATOM 1688 O O   . GLN B 2 185 ? 156.389 143.749 208.800 1.00 136.37 ? 185 GLN H O   1 
ATOM 1689 C CB  . GLN B 2 185 ? 155.284 146.299 210.680 1.00 136.37 ? 185 GLN H CB  1 
ATOM 1690 C CG  . GLN B 2 185 ? 154.260 147.409 210.796 1.00 136.37 ? 185 GLN H CG  1 
ATOM 1691 C CD  . GLN B 2 185 ? 154.865 148.774 210.571 1.00 136.37 ? 185 GLN H CD  1 
ATOM 1692 O OE1 . GLN B 2 185 ? 156.010 149.024 210.945 1.00 136.37 ? 185 GLN H OE1 1 
ATOM 1693 N NE2 . GLN B 2 185 ? 154.102 149.667 209.949 1.00 136.37 ? 185 GLN H NE2 1 
ATOM 1694 N N   . SER B 2 186 ? 157.929 145.068 209.792 1.00 139.29 ? 186 SER H N   1 
ATOM 1695 C CA  . SER B 2 186 ? 158.887 143.980 209.939 1.00 139.29 ? 186 SER H CA  1 
ATOM 1696 C C   . SER B 2 186 ? 158.375 142.891 210.872 1.00 139.29 ? 186 SER H C   1 
ATOM 1697 O O   . SER B 2 186 ? 158.872 141.761 210.823 1.00 139.29 ? 186 SER H O   1 
ATOM 1698 C CB  . SER B 2 186 ? 160.222 144.522 210.451 1.00 139.29 ? 186 SER H CB  1 
ATOM 1699 O OG  . SER B 2 186 ? 160.077 145.090 211.742 1.00 139.29 ? 186 SER H OG  1 
ATOM 1700 N N   . SER B 2 187 ? 157.397 143.205 211.718 1.00 139.58 ? 187 SER H N   1 
ATOM 1701 C CA  . SER B 2 187 ? 156.781 142.217 212.590 1.00 139.58 ? 187 SER H CA  1 
ATOM 1702 C C   . SER B 2 187 ? 155.751 141.359 211.874 1.00 139.58 ? 187 SER H C   1 
ATOM 1703 O O   . SER B 2 187 ? 155.256 140.392 212.463 1.00 139.58 ? 187 SER H O   1 
ATOM 1704 C CB  . SER B 2 187 ? 156.115 142.909 213.782 1.00 139.58 ? 187 SER H CB  1 
ATOM 1705 O OG  . SER B 2 187 ? 154.950 143.608 213.375 1.00 139.58 ? 187 SER H OG  1 
ATOM 1706 N N   . GLY B 2 188 ? 155.407 141.691 210.633 1.00 137.36 ? 188 GLY H N   1 
ATOM 1707 C CA  . GLY B 2 188 ? 154.384 140.976 209.910 1.00 137.36 ? 188 GLY H CA  1 
ATOM 1708 C C   . GLY B 2 188 ? 152.992 141.522 210.096 1.00 137.36 ? 188 GLY H C   1 
ATOM 1709 O O   . GLY B 2 188 ? 152.070 141.075 209.402 1.00 137.36 ? 188 GLY H O   1 
ATOM 1710 N N   . LEU B 2 189 ? 152.808 142.471 211.003 1.00 135.29 ? 189 LEU H N   1 
ATOM 1711 C CA  . LEU B 2 189 ? 151.525 143.124 211.191 1.00 135.29 ? 189 LEU H CA  1 
ATOM 1712 C C   . LEU B 2 189 ? 151.451 144.389 210.344 1.00 135.29 ? 189 LEU H C   1 
ATOM 1713 O O   . LEU B 2 189 ? 152.459 144.909 209.862 1.00 135.29 ? 189 LEU H O   1 
ATOM 1714 C CB  . LEU B 2 189 ? 151.308 143.462 212.664 1.00 135.29 ? 189 LEU H CB  1 
ATOM 1715 C CG  . LEU B 2 189 ? 151.672 142.323 213.613 1.00 135.29 ? 189 LEU H CG  1 
ATOM 1716 C CD1 . LEU B 2 189 ? 151.796 142.817 215.044 1.00 135.29 ? 189 LEU H CD1 1 
ATOM 1717 C CD2 . LEU B 2 189 ? 150.635 141.224 213.508 1.00 135.29 ? 189 LEU H CD2 1 
ATOM 1718 N N   . TYR B 2 190 ? 150.235 144.883 210.179 1.00 132.42 ? 190 TYR H N   1 
ATOM 1719 C CA  . TYR B 2 190 ? 149.972 146.070 209.387 1.00 132.42 ? 190 TYR H CA  1 
ATOM 1720 C C   . TYR B 2 190 ? 149.699 147.264 210.291 1.00 132.42 ? 190 TYR H C   1 
ATOM 1721 O O   . TYR B 2 190 ? 149.200 147.132 211.416 1.00 132.42 ? 190 TYR H O   1 
ATOM 1722 C CB  . TYR B 2 190 ? 148.783 145.850 208.449 1.00 132.42 ? 190 TYR H CB  1 
ATOM 1723 C CG  . TYR B 2 190 ? 149.038 144.847 207.347 1.00 132.42 ? 190 TYR H CG  1 
ATOM 1724 C CD1 . TYR B 2 190 ? 149.762 145.201 206.217 1.00 132.42 ? 190 TYR H CD1 1 
ATOM 1725 C CD2 . TYR B 2 190 ? 148.553 143.549 207.435 1.00 132.42 ? 190 TYR H CD2 1 
ATOM 1726 C CE1 . TYR B 2 190 ? 149.995 144.294 205.207 1.00 132.42 ? 190 TYR H CE1 1 
ATOM 1727 C CE2 . TYR B 2 190 ? 148.784 142.634 206.429 1.00 132.42 ? 190 TYR H CE2 1 
ATOM 1728 C CZ  . TYR B 2 190 ? 149.505 143.013 205.318 1.00 132.42 ? 190 TYR H CZ  1 
ATOM 1729 O OH  . TYR B 2 190 ? 149.740 142.106 204.312 1.00 132.42 ? 190 TYR H OH  1 
ATOM 1730 N N   . SER B 2 191 ? 150.049 148.438 209.768 1.00 127.03 ? 191 SER H N   1 
ATOM 1731 C CA  . SER B 2 191 ? 149.795 149.725 210.403 1.00 127.03 ? 191 SER H CA  1 
ATOM 1732 C C   . SER B 2 191 ? 149.243 150.676 209.353 1.00 127.03 ? 191 SER H C   1 
ATOM 1733 O O   . SER B 2 191 ? 149.538 150.543 208.158 1.00 127.03 ? 191 SER H O   1 
ATOM 1734 C CB  . SER B 2 191 ? 151.069 150.315 211.025 1.00 127.03 ? 191 SER H CB  1 
ATOM 1735 O OG  . SER B 2 191 ? 151.703 149.386 211.888 1.00 127.03 ? 191 SER H OG  1 
ATOM 1736 N N   . LEU B 2 192 ? 148.451 151.641 209.798 1.00 120.46 ? 192 LEU H N   1 
ATOM 1737 C CA  . LEU B 2 192 ? 147.736 152.531 208.901 1.00 120.46 ? 192 LEU H CA  1 
ATOM 1738 C C   . LEU B 2 192 ? 147.500 153.855 209.606 1.00 120.46 ? 192 LEU H C   1 
ATOM 1739 O O   . LEU B 2 192 ? 147.200 153.888 210.797 1.00 120.46 ? 192 LEU H O   1 
ATOM 1740 C CB  . LEU B 2 192 ? 146.412 151.895 208.462 1.00 120.46 ? 192 LEU H CB  1 
ATOM 1741 C CG  . LEU B 2 192 ? 145.316 152.679 207.745 1.00 120.46 ? 192 LEU H CG  1 
ATOM 1742 C CD1 . LEU B 2 192 ? 144.518 151.729 206.881 1.00 120.46 ? 192 LEU H CD1 1 
ATOM 1743 C CD2 . LEU B 2 192 ? 144.392 153.358 208.734 1.00 120.46 ? 192 LEU H CD2 1 
ATOM 1744 N N   . SER B 2 193 ? 147.640 154.950 208.867 1.00 115.32 ? 193 SER H N   1 
ATOM 1745 C CA  . SER B 2 193 ? 147.336 156.282 209.372 1.00 115.32 ? 193 SER H CA  1 
ATOM 1746 C C   . SER B 2 193 ? 146.145 156.862 208.622 1.00 115.32 ? 193 SER H C   1 
ATOM 1747 O O   . SER B 2 193 ? 145.916 156.552 207.450 1.00 115.32 ? 193 SER H O   1 
ATOM 1748 C CB  . SER B 2 193 ? 148.544 157.212 209.243 1.00 115.32 ? 193 SER H CB  1 
ATOM 1749 O OG  . SER B 2 193 ? 149.072 157.176 207.930 1.00 115.32 ? 193 SER H OG  1 
ATOM 1750 N N   . SER B 2 194 ? 145.382 157.705 209.308 1.00 119.38 ? 194 SER H N   1 
ATOM 1751 C CA  . SER B 2 194 ? 144.186 158.305 208.731 1.00 119.38 ? 194 SER H CA  1 
ATOM 1752 C C   . SER B 2 194 ? 144.055 159.730 209.237 1.00 119.38 ? 194 SER H C   1 
ATOM 1753 O O   . SER B 2 194 ? 144.179 159.971 210.440 1.00 119.38 ? 194 SER H O   1 
ATOM 1754 C CB  . SER B 2 194 ? 142.937 157.499 209.093 1.00 119.38 ? 194 SER H CB  1 
ATOM 1755 O OG  . SER B 2 194 ? 141.780 158.061 208.503 1.00 119.38 ? 194 SER H OG  1 
ATOM 1756 N N   . VAL B 2 195 ? 143.805 160.675 208.329 1.00 118.48 ? 195 VAL H N   1 
ATOM 1757 C CA  . VAL B 2 195 ? 143.753 162.085 208.696 1.00 118.48 ? 195 VAL H CA  1 
ATOM 1758 C C   . VAL B 2 195 ? 142.547 162.755 208.055 1.00 118.48 ? 195 VAL H C   1 
ATOM 1759 O O   . VAL B 2 195 ? 142.047 162.321 207.015 1.00 118.48 ? 195 VAL H O   1 
ATOM 1760 C CB  . VAL B 2 195 ? 145.049 162.810 208.292 1.00 118.48 ? 195 VAL H CB  1 
ATOM 1761 C CG1 . VAL B 2 195 ? 146.203 162.354 209.169 1.00 118.48 ? 195 VAL H CG1 1 
ATOM 1762 C CG2 . VAL B 2 195 ? 145.344 162.545 206.828 1.00 118.48 ? 195 VAL H CG2 1 
ATOM 1763 N N   . VAL B 2 196 ? 142.057 163.809 208.711 1.00 124.98 ? 196 VAL H N   1 
ATOM 1764 C CA  . VAL B 2 196 ? 141.116 164.751 208.117 1.00 124.98 ? 196 VAL H CA  1 
ATOM 1765 C C   . VAL B 2 196 ? 141.557 166.152 208.519 1.00 124.98 ? 196 VAL H C   1 
ATOM 1766 O O   . VAL B 2 196 ? 142.364 166.335 209.433 1.00 124.98 ? 196 VAL H O   1 
ATOM 1767 C CB  . VAL B 2 196 ? 139.648 164.504 208.538 1.00 124.98 ? 196 VAL H CB  1 
ATOM 1768 C CG1 . VAL B 2 196 ? 139.216 163.086 208.212 1.00 124.98 ? 196 VAL H CG1 1 
ATOM 1769 C CG2 . VAL B 2 196 ? 139.466 164.787 209.997 1.00 124.98 ? 196 VAL H CG2 1 
ATOM 1770 N N   . THR B 2 197 ? 141.023 167.151 207.823 1.00 128.36 ? 197 THR H N   1 
ATOM 1771 C CA  . THR B 2 197 ? 141.364 168.544 208.076 1.00 128.36 ? 197 THR H CA  1 
ATOM 1772 C C   . THR B 2 197 ? 140.137 169.300 208.557 1.00 128.36 ? 197 THR H C   1 
ATOM 1773 O O   . THR B 2 197 ? 139.035 169.122 208.030 1.00 128.36 ? 197 THR H O   1 
ATOM 1774 C CB  . THR B 2 197 ? 141.933 169.222 206.830 1.00 128.36 ? 197 THR H CB  1 
ATOM 1775 O OG1 . THR B 2 197 ? 141.118 168.901 205.696 1.00 128.36 ? 197 THR H OG1 1 
ATOM 1776 C CG2 . THR B 2 197 ? 143.354 168.760 206.583 1.00 128.36 ? 197 THR H CG2 1 
ATOM 1777 N N   . VAL B 2 198 ? 140.339 170.140 209.566 1.00 140.17 ? 198 VAL H N   1 
ATOM 1778 C CA  . VAL B 2 198 ? 139.258 170.912 210.171 1.00 140.17 ? 198 VAL H CA  1 
ATOM 1779 C C   . VAL B 2 198 ? 139.759 172.333 210.425 1.00 140.17 ? 198 VAL H C   1 
ATOM 1780 O O   . VAL B 2 198 ? 140.960 172.572 210.540 1.00 140.17 ? 198 VAL H O   1 
ATOM 1781 C CB  . VAL B 2 198 ? 138.762 170.272 211.487 1.00 140.17 ? 198 VAL H CB  1 
ATOM 1782 C CG1 . VAL B 2 198 ? 138.073 168.938 211.210 1.00 140.17 ? 198 VAL H CG1 1 
ATOM 1783 C CG2 . VAL B 2 198 ? 139.916 170.093 212.460 1.00 140.17 ? 198 VAL H CG2 1 
ATOM 1784 N N   . PRO B 2 199 ? 138.830 173.286 210.509 1.00 148.65 ? 199 PRO H N   1 
ATOM 1785 C CA  . PRO B 2 199 ? 139.229 174.661 210.849 1.00 148.65 ? 199 PRO H CA  1 
ATOM 1786 C C   . PRO B 2 199 ? 139.899 174.743 212.213 1.00 148.65 ? 199 PRO H C   1 
ATOM 1787 O O   . PRO B 2 199 ? 139.582 173.995 213.140 1.00 148.65 ? 199 PRO H O   1 
ATOM 1788 C CB  . PRO B 2 199 ? 137.900 175.423 210.831 1.00 148.65 ? 199 PRO H CB  1 
ATOM 1789 C CG  . PRO B 2 199 ? 137.034 174.635 209.905 1.00 148.65 ? 199 PRO H CG  1 
ATOM 1790 C CD  . PRO B 2 199 ? 137.415 173.204 210.116 1.00 148.65 ? 199 PRO H CD  1 
ATOM 1791 N N   . SER B 2 200 ? 140.825 175.693 212.329 1.00 156.76 ? 200 SER H N   1 
ATOM 1792 C CA  . SER B 2 200 ? 141.690 175.850 213.493 1.00 156.76 ? 200 SER H CA  1 
ATOM 1793 C C   . SER B 2 200 ? 140.957 176.523 214.649 1.00 156.76 ? 200 SER H C   1 
ATOM 1794 O O   . SER B 2 200 ? 139.719 176.488 214.705 1.00 156.76 ? 200 SER H O   1 
ATOM 1795 C CB  . SER B 2 200 ? 142.946 176.641 213.129 1.00 156.76 ? 200 SER H CB  1 
ATOM 1796 O OG  . SER B 2 200 ? 143.957 176.453 214.101 1.00 156.76 ? 200 SER H OG  1 
ATOM 1797 N N   . SER B 2 201 ? 141.721 177.087 215.593 1.00 161.69 ? 201 SER H N   1 
ATOM 1798 C CA  . SER B 2 201 ? 141.222 177.555 216.884 1.00 161.69 ? 201 SER H CA  1 
ATOM 1799 C C   . SER B 2 201 ? 140.743 176.381 217.731 1.00 161.69 ? 201 SER H C   1 
ATOM 1800 O O   . SER B 2 201 ? 139.532 176.216 217.988 1.00 161.69 ? 201 SER H O   1 
ATOM 1801 C CB  . SER B 2 201 ? 140.106 178.592 216.708 1.00 161.69 ? 201 SER H CB  1 
ATOM 1802 O OG  . SER B 2 201 ? 139.632 179.055 217.960 1.00 161.69 ? 201 SER H OG  1 
ATOM 1803 N N   . SER B 2 202 ? 141.696 175.528 218.128 1.00 160.83 ? 202 SER H N   1 
ATOM 1804 C CA  . SER B 2 202 ? 141.427 174.311 218.898 1.00 160.83 ? 202 SER H CA  1 
ATOM 1805 C C   . SER B 2 202 ? 140.579 173.332 218.093 1.00 160.83 ? 202 SER H C   1 
ATOM 1806 O O   . SER B 2 202 ? 139.652 172.710 218.615 1.00 160.83 ? 202 SER H O   1 
ATOM 1807 C CB  . SER B 2 202 ? 140.769 174.623 220.245 1.00 160.83 ? 202 SER H CB  1 
ATOM 1808 O OG  . SER B 2 202 ? 141.592 175.461 221.036 1.00 160.83 ? 202 SER H OG  1 
ATOM 1809 N N   . LEU B 2 203 ? 140.915 173.193 216.809 1.00 159.35 ? 203 LEU H N   1 
ATOM 1810 C CA  . LEU B 2 203 ? 140.229 172.277 215.898 1.00 159.35 ? 203 LEU H CA  1 
ATOM 1811 C C   . LEU B 2 203 ? 138.730 172.559 215.864 1.00 159.35 ? 203 LEU H C   1 
ATOM 1812 O O   . LEU B 2 203 ? 137.902 171.642 215.855 1.00 159.35 ? 203 LEU H O   1 
ATOM 1813 C CB  . LEU B 2 203 ? 140.518 170.824 216.271 1.00 159.35 ? 203 LEU H CB  1 
ATOM 1814 C CG  . LEU B 2 203 ? 142.007 170.495 216.390 1.00 159.35 ? 203 LEU H CG  1 
ATOM 1815 C CD1 . LEU B 2 203 ? 142.211 169.113 216.996 1.00 159.35 ? 203 LEU H CD1 1 
ATOM 1816 C CD2 . LEU B 2 203 ? 142.677 170.602 215.030 1.00 159.35 ? 203 LEU H CD2 1 
ATOM 1817 N N   . GLY B 2 204 ? 138.379 173.850 215.840 1.00 158.52 ? 204 GLY H N   1 
ATOM 1818 C CA  . GLY B 2 204 ? 136.978 174.213 215.874 1.00 158.52 ? 204 GLY H CA  1 
ATOM 1819 C C   . GLY B 2 204 ? 136.305 173.993 217.208 1.00 158.52 ? 204 GLY H C   1 
ATOM 1820 O O   . GLY B 2 204 ? 135.083 173.850 217.253 1.00 158.52 ? 204 GLY H O   1 
ATOM 1821 N N   . THR B 2 205 ? 137.097 173.958 218.292 1.00 160.60 ? 205 THR H N   1 
ATOM 1822 C CA  . THR B 2 205 ? 136.654 173.670 219.667 1.00 160.60 ? 205 THR H CA  1 
ATOM 1823 C C   . THR B 2 205 ? 136.015 172.295 219.817 1.00 160.60 ? 205 THR H C   1 
ATOM 1824 O O   . THR B 2 205 ? 135.523 171.970 220.897 1.00 160.60 ? 205 THR H O   1 
ATOM 1825 C CB  . THR B 2 205 ? 135.671 174.721 220.212 1.00 160.60 ? 205 THR H CB  1 
ATOM 1826 O OG1 . THR B 2 205 ? 134.350 174.446 219.735 1.00 160.60 ? 205 THR H OG1 1 
ATOM 1827 C CG2 . THR B 2 205 ? 136.085 176.125 219.801 1.00 160.60 ? 205 THR H CG2 1 
ATOM 1828 N N   . GLN B 2 206 ? 136.017 171.485 218.764 1.00 155.50 ? 206 GLN H N   1 
ATOM 1829 C CA  . GLN B 2 206 ? 135.353 170.189 218.775 1.00 155.50 ? 206 GLN H CA  1 
ATOM 1830 C C   . GLN B 2 206 ? 136.335 169.076 219.118 1.00 155.50 ? 206 GLN H C   1 
ATOM 1831 O O   . GLN B 2 206 ? 137.483 169.079 218.662 1.00 155.50 ? 206 GLN H O   1 
ATOM 1832 C CB  . GLN B 2 206 ? 134.704 169.914 217.418 1.00 155.50 ? 206 GLN H CB  1 
ATOM 1833 C CG  . GLN B 2 206 ? 133.951 168.604 217.338 1.00 155.50 ? 206 GLN H CG  1 
ATOM 1834 C CD  . GLN B 2 206 ? 132.796 168.540 218.313 1.00 155.50 ? 206 GLN H CD  1 
ATOM 1835 O OE1 . GLN B 2 206 ? 132.060 169.512 218.488 1.00 155.50 ? 206 GLN H OE1 1 
ATOM 1836 N NE2 . GLN B 2 206 ? 132.633 167.393 218.960 1.00 155.50 ? 206 GLN H NE2 1 
ATOM 1837 N N   . THR B 2 207 ? 135.875 168.129 219.928 1.00 155.64 ? 207 THR H N   1 
ATOM 1838 C CA  . THR B 2 207 ? 136.610 166.900 220.190 1.00 155.64 ? 207 THR H CA  1 
ATOM 1839 C C   . THR B 2 207 ? 136.194 165.863 219.156 1.00 155.64 ? 207 THR H C   1 
ATOM 1840 O O   . THR B 2 207 ? 134.997 165.663 218.923 1.00 155.64 ? 207 THR H O   1 
ATOM 1841 C CB  . THR B 2 207 ? 136.331 166.388 221.605 1.00 155.64 ? 207 THR H CB  1 
ATOM 1842 O OG1 . THR B 2 207 ? 136.616 167.421 222.556 1.00 155.64 ? 207 THR H OG1 1 
ATOM 1843 C CG2 . THR B 2 207 ? 137.195 165.172 221.918 1.00 155.64 ? 207 THR H CG2 1 
ATOM 1844 N N   . TYR B 2 208 ? 137.172 165.208 218.537 1.00 149.74 ? 208 TYR H N   1 
ATOM 1845 C CA  . TYR B 2 208 ? 136.899 164.369 217.377 1.00 149.74 ? 208 TYR H CA  1 
ATOM 1846 C C   . TYR B 2 208 ? 137.107 162.895 217.705 1.00 149.74 ? 208 TYR H C   1 
ATOM 1847 O O   . TYR B 2 208 ? 137.858 162.547 218.613 1.00 149.74 ? 208 TYR H O   1 
ATOM 1848 C CB  . TYR B 2 208 ? 137.779 164.772 216.195 1.00 149.74 ? 208 TYR H CB  1 
ATOM 1849 C CG  . TYR B 2 208 ? 137.422 166.115 215.597 1.00 149.74 ? 208 TYR H CG  1 
ATOM 1850 C CD1 . TYR B 2 208 ? 136.368 166.239 214.705 1.00 149.74 ? 208 TYR H CD1 1 
ATOM 1851 C CD2 . TYR B 2 208 ? 138.150 167.256 215.912 1.00 149.74 ? 208 TYR H CD2 1 
ATOM 1852 C CE1 . TYR B 2 208 ? 136.042 167.460 214.149 1.00 149.74 ? 208 TYR H CE1 1 
ATOM 1853 C CE2 . TYR B 2 208 ? 137.832 168.483 215.357 1.00 149.74 ? 208 TYR H CE2 1 
ATOM 1854 C CZ  . TYR B 2 208 ? 136.776 168.579 214.478 1.00 149.74 ? 208 TYR H CZ  1 
ATOM 1855 O OH  . TYR B 2 208 ? 136.449 169.795 213.923 1.00 149.74 ? 208 TYR H OH  1 
ATOM 1856 N N   . ILE B 2 209 ? 136.418 162.028 216.967 1.00 146.27 ? 209 ILE H N   1 
ATOM 1857 C CA  . ILE B 2 209 ? 136.449 160.590 217.209 1.00 146.27 ? 209 ILE H CA  1 
ATOM 1858 C C   . ILE B 2 209 ? 137.048 159.895 215.992 1.00 146.27 ? 209 ILE H C   1 
ATOM 1859 O O   . ILE B 2 209 ? 136.586 160.098 214.864 1.00 146.27 ? 209 ILE H O   1 
ATOM 1860 C CB  . ILE B 2 209 ? 135.044 160.036 217.515 1.00 146.27 ? 209 ILE H CB  1 
ATOM 1861 C CG1 . ILE B 2 209 ? 134.428 160.774 218.705 1.00 146.27 ? 209 ILE H CG1 1 
ATOM 1862 C CG2 . ILE B 2 209 ? 135.119 158.556 217.816 1.00 146.27 ? 209 ILE H CG2 1 
ATOM 1863 C CD1 . ILE B 2 209 ? 135.264 160.697 219.961 1.00 146.27 ? 209 ILE H CD1 1 
ATOM 1864 N N   . CYS B 2 210 ? 138.079 159.083 216.223 1.00 144.05 ? 210 CYS H N   1 
ATOM 1865 C CA  . CYS B 2 210 ? 138.632 158.196 215.205 1.00 144.05 ? 210 CYS H CA  1 
ATOM 1866 C C   . CYS B 2 210 ? 138.104 156.794 215.492 1.00 144.05 ? 210 CYS H C   1 
ATOM 1867 O O   . CYS B 2 210 ? 138.397 156.222 216.547 1.00 144.05 ? 210 CYS H O   1 
ATOM 1868 C CB  . CYS B 2 210 ? 140.158 158.239 215.225 1.00 144.05 ? 210 CYS H CB  1 
ATOM 1869 S SG  . CYS B 2 210 ? 140.975 157.320 213.905 1.00 144.05 ? 210 CYS H SG  1 
ATOM 1870 N N   . ASN B 2 211 ? 137.297 156.257 214.577 1.00 144.48 ? 211 ASN H N   1 
ATOM 1871 C CA  . ASN B 2 211 ? 136.638 154.969 214.753 1.00 144.48 ? 211 ASN H CA  1 
ATOM 1872 C C   . ASN B 2 211 ? 137.301 153.945 213.839 1.00 144.48 ? 211 ASN H C   1 
ATOM 1873 O O   . ASN B 2 211 ? 137.324 154.122 212.616 1.00 144.48 ? 211 ASN H O   1 
ATOM 1874 C CB  . ASN B 2 211 ? 135.143 155.084 214.451 1.00 144.48 ? 211 ASN H CB  1 
ATOM 1875 C CG  . ASN B 2 211 ? 134.487 156.227 215.197 1.00 144.48 ? 211 ASN H CG  1 
ATOM 1876 O OD1 . ASN B 2 211 ? 134.655 157.393 214.840 1.00 144.48 ? 211 ASN H OD1 1 
ATOM 1877 N ND2 . ASN B 2 211 ? 133.732 155.898 216.238 1.00 144.48 ? 211 ASN H ND2 1 
ATOM 1878 N N   . VAL B 2 212 ? 137.836 152.876 214.428 1.00 145.08 ? 212 VAL H N   1 
ATOM 1879 C CA  . VAL B 2 212 ? 138.572 151.853 213.695 1.00 145.08 ? 212 VAL H CA  1 
ATOM 1880 C C   . VAL B 2 212 ? 137.911 150.503 213.931 1.00 145.08 ? 212 VAL H C   1 
ATOM 1881 O O   . VAL B 2 212 ? 137.601 150.147 215.075 1.00 145.08 ? 212 VAL H O   1 
ATOM 1882 C CB  . VAL B 2 212 ? 140.053 151.818 214.107 1.00 145.08 ? 212 VAL H CB  1 
ATOM 1883 C CG1 . VAL B 2 212 ? 140.812 150.840 213.235 1.00 145.08 ? 212 VAL H CG1 1 
ATOM 1884 C CG2 . VAL B 2 212 ? 140.652 153.205 213.999 1.00 145.08 ? 212 VAL H CG2 1 
ATOM 1885 N N   . ASN B 2 213 ? 137.697 149.756 212.848 1.00 146.73 ? 213 ASN H N   1 
ATOM 1886 C CA  . ASN B 2 213 ? 137.063 148.445 212.890 1.00 146.73 ? 213 ASN H CA  1 
ATOM 1887 C C   . ASN B 2 213 ? 137.954 147.440 212.177 1.00 146.73 ? 213 ASN H C   1 
ATOM 1888 O O   . ASN B 2 213 ? 138.296 147.627 211.005 1.00 146.73 ? 213 ASN H O   1 
ATOM 1889 C CB  . ASN B 2 213 ? 135.676 148.481 212.241 1.00 146.73 ? 213 ASN H CB  1 
ATOM 1890 C CG  . ASN B 2 213 ? 134.730 149.429 212.946 1.00 146.73 ? 213 ASN H CG  1 
ATOM 1891 O OD1 . ASN B 2 213 ? 133.917 149.012 213.770 1.00 146.73 ? 213 ASN H OD1 1 
ATOM 1892 N ND2 . ASN B 2 213 ? 134.830 150.714 212.626 1.00 146.73 ? 213 ASN H ND2 1 
ATOM 1893 N N   . HIS B 2 214 ? 138.326 146.383 212.889 1.00 144.37 ? 214 HIS H N   1 
ATOM 1894 C CA  . HIS B 2 214 ? 139.039 145.242 212.333 1.00 144.37 ? 214 HIS H CA  1 
ATOM 1895 C C   . HIS B 2 214 ? 138.108 144.039 212.440 1.00 144.37 ? 214 HIS H C   1 
ATOM 1896 O O   . HIS B 2 214 ? 137.882 143.515 213.538 1.00 144.37 ? 214 HIS H O   1 
ATOM 1897 C CB  . HIS B 2 214 ? 140.355 145.010 213.068 1.00 144.37 ? 214 HIS H CB  1 
ATOM 1898 C CG  . HIS B 2 214 ? 141.212 143.951 212.454 1.00 144.37 ? 214 HIS H CG  1 
ATOM 1899 N ND1 . HIS B 2 214 ? 141.255 142.660 212.932 1.00 144.37 ? 214 HIS H ND1 1 
ATOM 1900 C CD2 . HIS B 2 214 ? 142.064 143.991 211.403 1.00 144.37 ? 214 HIS H CD2 1 
ATOM 1901 C CE1 . HIS B 2 214 ? 142.099 141.951 212.204 1.00 144.37 ? 214 HIS H CE1 1 
ATOM 1902 N NE2 . HIS B 2 214 ? 142.600 142.735 211.267 1.00 144.37 ? 214 HIS H NE2 1 
ATOM 1903 N N   . LYS B 2 215 ? 137.544 143.638 211.302 1.00 143.70 ? 215 LYS H N   1 
ATOM 1904 C CA  . LYS B 2 215 ? 136.613 142.511 211.254 1.00 143.70 ? 215 LYS H CA  1 
ATOM 1905 C C   . LYS B 2 215 ? 137.219 141.187 211.717 1.00 143.70 ? 215 LYS H C   1 
ATOM 1906 O O   . LYS B 2 215 ? 136.556 140.473 212.490 1.00 143.70 ? 215 LYS H O   1 
ATOM 1907 C CB  . LYS B 2 215 ? 136.046 142.403 209.833 1.00 143.70 ? 215 LYS H CB  1 
ATOM 1908 C CG  . LYS B 2 215 ? 135.121 141.226 209.608 1.00 143.70 ? 215 LYS H CG  1 
ATOM 1909 C CD  . LYS B 2 215 ? 134.677 141.161 208.156 1.00 143.70 ? 215 LYS H CD  1 
ATOM 1910 C CE  . LYS B 2 215 ? 133.714 140.008 207.919 1.00 143.70 ? 215 LYS H CE  1 
ATOM 1911 N NZ  . LYS B 2 215 ? 133.281 139.929 206.493 1.00 143.70 ? 215 LYS H NZ  1 
ATOM 1912 N N   . PRO B 2 216 ? 138.428 140.788 211.298 1.00 143.20 ? 216 PRO H N   1 
ATOM 1913 C CA  . PRO B 2 216 ? 138.928 139.455 211.683 1.00 143.20 ? 216 PRO H CA  1 
ATOM 1914 C C   . PRO B 2 216 ? 139.063 139.234 213.179 1.00 143.20 ? 216 PRO H C   1 
ATOM 1915 O O   . PRO B 2 216 ? 139.038 138.077 213.616 1.00 143.20 ? 216 PRO H O   1 
ATOM 1916 C CB  . PRO B 2 216 ? 140.293 139.380 210.989 1.00 143.20 ? 216 PRO H CB  1 
ATOM 1917 C CG  . PRO B 2 216 ? 140.171 140.301 209.834 1.00 143.20 ? 216 PRO H CG  1 
ATOM 1918 C CD  . PRO B 2 216 ? 139.319 141.430 210.314 1.00 143.20 ? 216 PRO H CD  1 
ATOM 1919 N N   . SER B 2 217 ? 139.225 140.283 213.980 1.00 144.76 ? 217 SER H N   1 
ATOM 1920 C CA  . SER B 2 217 ? 139.291 140.129 215.427 1.00 144.76 ? 217 SER H CA  1 
ATOM 1921 C C   . SER B 2 217 ? 138.094 140.742 216.137 1.00 144.76 ? 217 SER H C   1 
ATOM 1922 O O   . SER B 2 217 ? 138.078 140.780 217.370 1.00 144.76 ? 217 SER H O   1 
ATOM 1923 C CB  . SER B 2 217 ? 140.586 140.733 215.974 1.00 144.76 ? 217 SER H CB  1 
ATOM 1924 O OG  . SER B 2 217 ? 140.665 142.115 215.687 1.00 144.76 ? 217 SER H OG  1 
ATOM 1925 N N   . ASN B 2 218 ? 137.091 141.207 215.391 1.00 149.24 ? 218 ASN H N   1 
ATOM 1926 C CA  . ASN B 2 218 ? 135.911 141.859 215.957 1.00 149.24 ? 218 ASN H CA  1 
ATOM 1927 C C   . ASN B 2 218 ? 136.310 143.013 216.875 1.00 149.24 ? 218 ASN H C   1 
ATOM 1928 O O   . ASN B 2 218 ? 135.789 143.173 217.978 1.00 149.24 ? 218 ASN H O   1 
ATOM 1929 C CB  . ASN B 2 218 ? 135.027 140.850 216.694 1.00 149.24 ? 218 ASN H CB  1 
ATOM 1930 C CG  . ASN B 2 218 ? 134.521 139.751 215.783 1.00 149.24 ? 218 ASN H CG  1 
ATOM 1931 O OD1 . ASN B 2 218 ? 134.302 139.970 214.591 1.00 149.24 ? 218 ASN H OD1 1 
ATOM 1932 N ND2 . ASN B 2 218 ? 134.336 138.560 216.337 1.00 149.24 ? 218 ASN H ND2 1 
ATOM 1933 N N   . THR B 2 219 ? 137.251 143.827 216.404 1.00 148.34 ? 219 THR H N   1 
ATOM 1934 C CA  . THR B 2 219 ? 137.782 144.936 217.188 1.00 148.34 ? 219 THR H CA  1 
ATOM 1935 C C   . THR B 2 219 ? 137.167 146.244 216.713 1.00 148.34 ? 219 THR H C   1 
ATOM 1936 O O   . THR B 2 219 ? 137.172 146.536 215.515 1.00 148.34 ? 219 THR H O   1 
ATOM 1937 C CB  . THR B 2 219 ? 139.305 144.999 217.078 1.00 148.34 ? 219 THR H CB  1 
ATOM 1938 O OG1 . THR B 2 219 ? 139.876 143.868 217.744 1.00 148.34 ? 219 THR H OG1 1 
ATOM 1939 C CG2 . THR B 2 219 ? 139.833 146.270 217.716 1.00 148.34 ? 219 THR H CG2 1 
ATOM 1940 N N   . LYS B 2 220 ? 136.625 147.017 217.651 1.00 149.55 ? 220 LYS H N   1 
ATOM 1941 C CA  . LYS B 2 220 ? 136.065 148.332 217.361 1.00 149.55 ? 220 LYS H CA  1 
ATOM 1942 C C   . LYS B 2 220 ? 136.563 149.309 218.413 1.00 149.55 ? 220 LYS H C   1 
ATOM 1943 O O   . LYS B 2 220 ? 136.241 149.166 219.596 1.00 149.55 ? 220 LYS H O   1 
ATOM 1944 C CB  . LYS B 2 220 ? 134.536 148.292 217.335 1.00 149.55 ? 220 LYS H CB  1 
ATOM 1945 C CG  . LYS B 2 220 ? 133.896 149.620 216.976 1.00 149.55 ? 220 LYS H CG  1 
ATOM 1946 C CD  . LYS B 2 220 ? 132.389 149.496 216.847 1.00 149.55 ? 220 LYS H CD  1 
ATOM 1947 C CE  . LYS B 2 220 ? 131.763 150.837 216.503 1.00 149.55 ? 220 LYS H CE  1 
ATOM 1948 N NZ  . LYS B 2 220 ? 132.150 151.890 217.481 1.00 149.55 ? 220 LYS H NZ  1 
ATOM 1949 N N   . VAL B 2 221 ? 137.344 150.297 217.984 1.00 149.31 ? 221 VAL H N   1 
ATOM 1950 C CA  . VAL B 2 221 ? 138.002 151.226 218.897 1.00 149.31 ? 221 VAL H CA  1 
ATOM 1951 C C   . VAL B 2 221 ? 137.685 152.650 218.460 1.00 149.31 ? 221 VAL H C   1 
ATOM 1952 O O   . VAL B 2 221 ? 137.961 153.028 217.316 1.00 149.31 ? 221 VAL H O   1 
ATOM 1953 C CB  . VAL B 2 221 ? 139.522 150.999 218.949 1.00 149.31 ? 221 VAL H CB  1 
ATOM 1954 C CG1 . VAL B 2 221 ? 140.153 151.884 220.009 1.00 149.31 ? 221 VAL H CG1 1 
ATOM 1955 C CG2 . VAL B 2 221 ? 139.828 149.540 219.229 1.00 149.31 ? 221 VAL H CG2 1 
ATOM 1956 N N   . ASP B 2 222 ? 137.118 153.437 219.374 1.00 150.21 ? 222 ASP H N   1 
ATOM 1957 C CA  . ASP B 2 222 ? 136.794 154.842 219.142 1.00 150.21 ? 222 ASP H CA  1 
ATOM 1958 C C   . ASP B 2 222 ? 137.678 155.670 220.062 1.00 150.21 ? 222 ASP H C   1 
ATOM 1959 O O   . ASP B 2 222 ? 137.532 155.611 221.287 1.00 150.21 ? 222 ASP H O   1 
ATOM 1960 C CB  . ASP B 2 222 ? 135.317 155.118 219.413 1.00 150.21 ? 222 ASP H CB  1 
ATOM 1961 C CG  . ASP B 2 222 ? 134.413 154.045 218.854 1.00 150.21 ? 222 ASP H CG  1 
ATOM 1962 O OD1 . ASP B 2 222 ? 134.737 153.496 217.781 1.00 150.21 ? 222 ASP H OD1 1 
ATOM 1963 O OD2 . ASP B 2 222 ? 133.381 153.746 219.490 1.00 150.21 ? 222 ASP H OD2 1 
ATOM 1964 N N   . LYS B 2 223 ? 138.590 156.441 219.484 1.00 147.34 ? 223 LYS H N   1 
ATOM 1965 C CA  . LYS B 2 223 ? 139.564 157.168 220.283 1.00 147.34 ? 223 LYS H CA  1 
ATOM 1966 C C   . LYS B 2 223 ? 139.471 158.663 220.013 1.00 147.34 ? 223 LYS H C   1 
ATOM 1967 O O   . LYS B 2 223 ? 139.183 159.094 218.893 1.00 147.34 ? 223 LYS H O   1 
ATOM 1968 C CB  . LYS B 2 223 ? 140.982 156.659 220.024 1.00 147.34 ? 223 LYS H CB  1 
ATOM 1969 C CG  . LYS B 2 223 ? 141.318 155.367 220.751 1.00 221.01 ? 223 LYS H CG  1 
ATOM 1970 C CD  . LYS B 2 223 ? 141.251 155.541 222.262 1.00 221.01 ? 223 LYS H CD  1 
ATOM 1971 C CE  . LYS B 2 223 ? 141.539 154.234 222.989 1.00 221.01 ? 223 LYS H CE  1 
ATOM 1972 N NZ  . LYS B 2 223 ? 141.407 154.375 224.467 1.00 221.01 ? 223 LYS H NZ  1 
ATOM 1973 N N   . LYS B 2 224 ? 139.710 159.448 221.059 1.00 149.45 ? 224 LYS H N   1 
ATOM 1974 C CA  . LYS B 2 224 ? 139.459 160.881 221.022 1.00 149.45 ? 224 LYS H CA  1 
ATOM 1975 C C   . LYS B 2 224 ? 140.678 161.667 220.564 1.00 149.45 ? 224 LYS H C   1 
ATOM 1976 O O   . LYS B 2 224 ? 141.818 161.363 220.930 1.00 149.45 ? 224 LYS H O   1 
ATOM 1977 C CB  . LYS B 2 224 ? 139.021 161.391 222.393 1.00 149.45 ? 224 LYS H CB  1 
ATOM 1978 C CG  . LYS B 2 224 ? 137.597 161.037 222.767 1.00 149.45 ? 224 LYS H CG  1 
ATOM 1979 C CD  . LYS B 2 224 ? 137.198 161.712 224.067 1.00 149.45 ? 224 LYS H CD  1 
ATOM 1980 C CE  . LYS B 2 224 ? 135.759 161.403 224.440 1.00 149.45 ? 224 LYS H CE  1 
ATOM 1981 N NZ  . LYS B 2 224 ? 135.346 162.138 225.669 1.00 149.45 ? 224 LYS H NZ  1 
ATOM 1982 N N   . VAL B 2 225 ? 140.414 162.697 219.772 1.00 146.16 ? 225 VAL H N   1 
ATOM 1983 C CA  . VAL B 2 225 ? 141.398 163.685 219.361 1.00 146.16 ? 225 VAL H CA  1 
ATOM 1984 C C   . VAL B 2 225 ? 140.994 165.005 220.007 1.00 146.16 ? 225 VAL H C   1 
ATOM 1985 O O   . VAL B 2 225 ? 139.876 165.496 219.788 1.00 146.16 ? 225 VAL H O   1 
ATOM 1986 C CB  . VAL B 2 225 ? 141.471 163.805 217.832 1.00 146.16 ? 225 VAL H CB  1 
ATOM 1987 C CG1 . VAL B 2 225 ? 142.779 164.460 217.412 1.00 146.16 ? 225 VAL H CG1 1 
ATOM 1988 C CG2 . VAL B 2 225 ? 141.311 162.435 217.187 1.00 146.16 ? 225 VAL H CG2 1 
ATOM 1989 N N   . GLU B 2 226 ? 141.900 165.558 220.822 1.00 150.43 ? 226 GLU H N   1 
ATOM 1990 C CA  . GLU B 2 226 ? 141.708 166.796 221.567 1.00 150.43 ? 226 GLU H CA  1 
ATOM 1991 C C   . GLU B 2 226 ? 143.001 167.596 221.454 1.00 150.43 ? 226 GLU H C   1 
ATOM 1992 O O   . GLU B 2 226 ? 144.083 167.055 221.737 1.00 150.43 ? 226 GLU H O   1 
ATOM 1993 C CB  . GLU B 2 226 ? 141.371 166.530 223.038 1.00 150.43 ? 226 GLU H CB  1 
ATOM 1994 C CG  . GLU B 2 226 ? 141.319 167.780 223.906 1.00 150.43 ? 226 GLU H CG  1 
ATOM 1995 C CD  . GLU B 2 226 ? 141.163 167.464 225.380 1.00 150.43 ? 226 GLU H CD  1 
ATOM 1996 O OE1 . GLU B 2 226 ? 141.094 166.266 225.727 1.00 150.43 ? 226 GLU H OE1 1 
ATOM 1997 O OE2 . GLU B 2 226 ? 141.111 168.415 226.189 1.00 150.43 ? 226 GLU H OE2 1 
ATOM 1998 N N   . PRO B 2 227 ? 142.927 168.877 221.089 1.00 152.87 ? 227 PRO H N   1 
ATOM 1999 C CA  . PRO B 2 227 ? 144.149 169.633 220.776 1.00 152.87 ? 227 PRO H CA  1 
ATOM 2000 C C   . PRO B 2 227 ? 145.123 169.677 221.946 1.00 152.87 ? 227 PRO H C   1 
ATOM 2001 O O   . PRO B 2 227 ? 144.729 169.699 223.112 1.00 152.87 ? 227 PRO H O   1 
ATOM 2002 C CB  . PRO B 2 227 ? 143.623 171.036 220.444 1.00 152.87 ? 227 PRO H CB  1 
ATOM 2003 C CG  . PRO B 2 227 ? 142.176 170.852 220.134 1.00 152.87 ? 227 PRO H CG  1 
ATOM 2004 C CD  . PRO B 2 227 ? 141.710 169.690 220.944 1.00 152.87 ? 227 PRO H CD  1 
ATOM 2005 N N   . LYS B 2 228 ? 146.413 169.668 221.617 1.00 153.58 ? 228 LYS H N   1 
ATOM 2006 C CA  . LYS B 2 228 ? 147.462 169.833 222.620 1.00 153.58 ? 228 LYS H CA  1 
ATOM 2007 C C   . LYS B 2 228 ? 148.135 171.193 222.469 1.00 153.58 ? 228 LYS H C   1 
ATOM 2008 O O   . LYS B 2 228 ? 149.343 171.281 222.253 1.00 153.58 ? 228 LYS H O   1 
ATOM 2009 C CB  . LYS B 2 228 ? 148.501 168.716 222.515 1.00 153.58 ? 228 LYS H CB  1 
ATOM 2010 C CG  . LYS B 2 228 ? 147.977 167.356 222.925 1.00 153.58 ? 228 LYS H CG  1 
ATOM 2011 C CD  . LYS B 2 228 ? 147.326 167.422 224.294 1.00 153.58 ? 228 LYS H CD  1 
ATOM 2012 C CE  . LYS B 2 228 ? 146.659 166.103 224.651 1.00 153.58 ? 228 LYS H CE  1 
ATOM 2013 N NZ  . LYS B 2 228 ? 145.929 166.170 225.949 1.00 153.58 ? 228 LYS H NZ  1 
ATOM 2014 N N   . GLN C 3 7   ? 178.250 175.340 191.492 1.00 146.46 ? 1   GLN K N   1 
ATOM 2015 C CA  . GLN C 3 7   ? 179.099 175.235 190.311 1.00 146.46 ? 1   GLN K CA  1 
ATOM 2016 C C   . GLN C 3 7   ? 178.326 175.603 189.050 1.00 146.46 ? 1   GLN K C   1 
ATOM 2017 O O   . GLN C 3 7   ? 178.788 176.403 188.237 1.00 146.46 ? 1   GLN K O   1 
ATOM 2018 C CB  . GLN C 3 7   ? 179.672 173.821 190.182 1.00 146.46 ? 1   GLN K CB  1 
ATOM 2019 C CG  . GLN C 3 7   ? 180.621 173.424 191.301 1.00 146.46 ? 1   GLN K CG  1 
ATOM 2020 C CD  . GLN C 3 7   ? 181.185 172.027 191.122 1.00 146.46 ? 1   GLN K CD  1 
ATOM 2021 O OE1 . GLN C 3 7   ? 180.638 171.213 190.376 1.00 146.46 ? 1   GLN K OE1 1 
ATOM 2022 N NE2 . GLN C 3 7   ? 182.289 171.743 191.804 1.00 146.46 ? 1   GLN K NE2 1 
ATOM 2023 N N   . VAL C 3 8   ? 177.143 175.009 188.896 1.00 144.00 ? 2   VAL K N   1 
ATOM 2024 C CA  . VAL C 3 8   ? 176.307 175.275 187.733 1.00 144.00 ? 2   VAL K CA  1 
ATOM 2025 C C   . VAL C 3 8   ? 175.787 176.704 187.798 1.00 144.00 ? 2   VAL K C   1 
ATOM 2026 O O   . VAL C 3 8   ? 175.241 177.137 188.821 1.00 144.00 ? 2   VAL K O   1 
ATOM 2027 C CB  . VAL C 3 8   ? 175.151 174.269 187.666 1.00 144.00 ? 2   VAL K CB  1 
ATOM 2028 C CG1 . VAL C 3 8   ? 174.323 174.483 186.407 1.00 144.00 ? 2   VAL K CG1 1 
ATOM 2029 C CG2 . VAL C 3 8   ? 175.683 172.845 187.739 1.00 144.00 ? 2   VAL K CG2 1 
ATOM 2030 N N   . GLN C 3 9   ? 175.950 177.443 186.706 1.00 145.68 ? 3   GLN K N   1 
ATOM 2031 C CA  . GLN C 3 9   ? 175.452 178.807 186.619 1.00 145.68 ? 3   GLN K CA  1 
ATOM 2032 C C   . GLN C 3 9   ? 174.197 178.859 185.759 1.00 145.68 ? 3   GLN K C   1 
ATOM 2033 O O   . GLN C 3 9   ? 174.000 178.040 184.858 1.00 145.68 ? 3   GLN K O   1 
ATOM 2034 C CB  . GLN C 3 9   ? 176.511 179.751 186.043 1.00 145.68 ? 3   GLN K CB  1 
ATOM 2035 C CG  . GLN C 3 9   ? 177.795 179.803 186.845 1.00 145.68 ? 3   GLN K CG  1 
ATOM 2036 C CD  . GLN C 3 9   ? 177.570 180.262 188.268 1.00 145.68 ? 3   GLN K CD  1 
ATOM 2037 O OE1 . GLN C 3 9   ? 176.942 181.293 188.508 1.00 145.68 ? 3   GLN K OE1 1 
ATOM 2038 N NE2 . GLN C 3 9   ? 178.074 179.491 189.224 1.00 145.68 ? 3   GLN K NE2 1 
ATOM 2039 N N   . LEU C 3 10  ? 173.344 179.831 186.052 1.00 137.23 ? 4   LEU K N   1 
ATOM 2040 C CA  . LEU C 3 10  ? 172.150 180.083 185.260 1.00 137.23 ? 4   LEU K CA  1 
ATOM 2041 C C   . LEU C 3 10  ? 172.165 181.525 184.785 1.00 137.23 ? 4   LEU K C   1 
ATOM 2042 O O   . LEU C 3 10  ? 172.233 182.454 185.599 1.00 137.23 ? 4   LEU K O   1 
ATOM 2043 C CB  . LEU C 3 10  ? 170.877 179.798 186.056 1.00 137.23 ? 4   LEU K CB  1 
ATOM 2044 C CG  . LEU C 3 10  ? 170.499 178.326 186.187 1.00 137.23 ? 4   LEU K CG  1 
ATOM 2045 C CD1 . LEU C 3 10  ? 169.200 178.174 186.956 1.00 137.23 ? 4   LEU K CD1 1 
ATOM 2046 C CD2 . LEU C 3 10  ? 170.383 177.691 184.817 1.00 137.23 ? 4   LEU K CD2 1 
ATOM 2047 N N   . GLN C 3 11  ? 172.099 181.707 183.473 1.00 136.87 ? 5   GLN K N   1 
ATOM 2048 C CA  . GLN C 3 11  ? 171.869 183.009 182.874 1.00 136.87 ? 5   GLN K CA  1 
ATOM 2049 C C   . GLN C 3 11  ? 170.386 183.126 182.565 1.00 136.87 ? 5   GLN K C   1 
ATOM 2050 O O   . GLN C 3 11  ? 169.721 182.129 182.287 1.00 136.87 ? 5   GLN K O   1 
ATOM 2051 C CB  . GLN C 3 11  ? 172.690 183.186 181.596 1.00 136.87 ? 5   GLN K CB  1 
ATOM 2052 C CG  . GLN C 3 11  ? 174.119 182.670 181.686 1.00 136.87 ? 5   GLN K CG  1 
ATOM 2053 C CD  . GLN C 3 11  ? 175.000 183.536 182.558 1.00 136.87 ? 5   GLN K CD  1 
ATOM 2054 O OE1 . GLN C 3 11  ? 175.010 184.760 182.429 1.00 136.87 ? 5   GLN K OE1 1 
ATOM 2055 N NE2 . GLN C 3 11  ? 175.745 182.905 183.457 1.00 136.87 ? 5   GLN K NE2 1 
ATOM 2056 N N   . GLU C 3 12  ? 169.863 184.344 182.629 1.00 134.55 ? 6   GLU K N   1 
ATOM 2057 C CA  . GLU C 3 12  ? 168.445 184.530 182.371 1.00 134.55 ? 6   GLU K CA  1 
ATOM 2058 C C   . GLU C 3 12  ? 168.208 185.965 181.936 1.00 134.55 ? 6   GLU K C   1 
ATOM 2059 O O   . GLU C 3 12  ? 168.825 186.890 182.469 1.00 134.55 ? 6   GLU K O   1 
ATOM 2060 C CB  . GLU C 3 12  ? 167.611 184.198 183.611 1.00 134.55 ? 6   GLU K CB  1 
ATOM 2061 C CG  . GLU C 3 12  ? 166.116 184.145 183.376 1.00 134.55 ? 6   GLU K CG  1 
ATOM 2062 C CD  . GLU C 3 12  ? 165.372 183.658 184.598 1.00 134.55 ? 6   GLU K CD  1 
ATOM 2063 O OE1 . GLU C 3 12  ? 166.040 183.252 185.570 1.00 134.55 ? 6   GLU K OE1 1 
ATOM 2064 O OE2 . GLU C 3 12  ? 164.127 183.685 184.597 1.00 134.55 ? 6   GLU K OE2 1 
ATOM 2065 N N   . SER C 3 13  ? 167.308 186.139 180.975 1.00 129.95 ? 7   SER K N   1 
ATOM 2066 C CA  . SER C 3 13  ? 166.999 187.457 180.443 1.00 129.95 ? 7   SER K CA  1 
ATOM 2067 C C   . SER C 3 13  ? 165.536 187.502 180.039 1.00 129.95 ? 7   SER K C   1 
ATOM 2068 O O   . SER C 3 13  ? 165.049 186.622 179.318 1.00 129.95 ? 7   SER K O   1 
ATOM 2069 C CB  . SER C 3 13  ? 167.899 187.798 179.252 1.00 129.95 ? 7   SER K CB  1 
ATOM 2070 O OG  . SER C 3 13  ? 167.612 189.090 178.746 1.00 129.95 ? 7   SER K OG  1 
ATOM 2071 N N   . GLY C 3 14  ? 164.840 188.515 180.538 1.00 126.87 ? 8   GLY K N   1 
ATOM 2072 C CA  . GLY C 3 14  ? 163.500 188.836 180.102 1.00 126.87 ? 8   GLY K CA  1 
ATOM 2073 C C   . GLY C 3 14  ? 163.526 190.178 179.413 1.00 126.87 ? 8   GLY K C   1 
ATOM 2074 O O   . GLY C 3 14  ? 164.569 190.586 178.895 1.00 126.87 ? 8   GLY K O   1 
ATOM 2075 N N   . GLY C 3 15  ? 162.402 190.882 179.407 1.00 128.88 ? 9   GLY K N   1 
ATOM 2076 C CA  . GLY C 3 15  ? 162.371 192.194 178.798 1.00 128.88 ? 9   GLY K CA  1 
ATOM 2077 C C   . GLY C 3 15  ? 162.300 193.319 179.808 1.00 128.88 ? 9   GLY K C   1 
ATOM 2078 O O   . GLY C 3 15  ? 162.856 193.222 180.906 1.00 128.88 ? 9   GLY K O   1 
ATOM 2079 N N   . GLY C 3 16  ? 161.622 194.400 179.433 1.00 134.05 ? 10  GLY K N   1 
ATOM 2080 C CA  . GLY C 3 16  ? 161.393 195.515 180.328 1.00 134.05 ? 10  GLY K CA  1 
ATOM 2081 C C   . GLY C 3 16  ? 159.918 195.770 180.557 1.00 134.05 ? 10  GLY K C   1 
ATOM 2082 O O   . GLY C 3 16  ? 159.175 194.859 180.932 1.00 134.05 ? 10  GLY K O   1 
ATOM 2083 N N   . LEU C 3 17  ? 159.481 197.005 180.329 1.00 136.96 ? 11  LEU K N   1 
ATOM 2084 C CA  . LEU C 3 17  ? 158.087 197.370 180.537 1.00 136.96 ? 11  LEU K CA  1 
ATOM 2085 C C   . LEU C 3 17  ? 157.258 197.011 179.314 1.00 136.96 ? 11  LEU K C   1 
ATOM 2086 O O   . LEU C 3 17  ? 157.601 197.388 178.189 1.00 136.96 ? 11  LEU K O   1 
ATOM 2087 C CB  . LEU C 3 17  ? 157.966 198.864 180.832 1.00 136.96 ? 11  LEU K CB  1 
ATOM 2088 C CG  . LEU C 3 17  ? 156.550 199.439 180.792 1.00 136.96 ? 11  LEU K CG  1 
ATOM 2089 C CD1 . LEU C 3 17  ? 155.669 198.778 181.836 1.00 136.96 ? 11  LEU K CD1 1 
ATOM 2090 C CD2 . LEU C 3 17  ? 156.580 200.945 180.990 1.00 136.96 ? 11  LEU K CD2 1 
ATOM 2091 N N   . VAL C 3 18  ? 156.163 196.283 179.536 1.00 134.95 ? 12  VAL K N   1 
ATOM 2092 C CA  . VAL C 3 18  ? 155.230 195.961 178.465 1.00 134.95 ? 12  VAL K CA  1 
ATOM 2093 C C   . VAL C 3 18  ? 153.816 196.316 178.909 1.00 134.95 ? 12  VAL K C   1 
ATOM 2094 O O   . VAL C 3 18  ? 153.521 196.430 180.099 1.00 134.95 ? 12  VAL K O   1 
ATOM 2095 C CB  . VAL C 3 18  ? 155.312 194.479 178.046 1.00 134.95 ? 12  VAL K CB  1 
ATOM 2096 C CG1 . VAL C 3 18  ? 156.700 194.158 177.540 1.00 134.95 ? 12  VAL K CG1 1 
ATOM 2097 C CG2 . VAL C 3 18  ? 154.948 193.582 179.206 1.00 134.95 ? 12  VAL K CG2 1 
ATOM 2098 N N   . GLN C 3 19  ? 152.945 196.514 177.926 1.00 137.85 ? 13  GLN K N   1 
ATOM 2099 C CA  . GLN C 3 19  ? 151.537 196.758 178.180 1.00 137.85 ? 13  GLN K CA  1 
ATOM 2100 C C   . GLN C 3 19  ? 150.804 195.443 178.408 1.00 137.85 ? 13  GLN K C   1 
ATOM 2101 O O   . GLN C 3 19  ? 151.258 194.386 177.963 1.00 137.85 ? 13  GLN K O   1 
ATOM 2102 C CB  . GLN C 3 19  ? 150.904 197.495 177.002 1.00 137.85 ? 13  GLN K CB  1 
ATOM 2103 C CG  . GLN C 3 19  ? 150.931 199.003 177.111 1.00 137.85 ? 13  GLN K CG  1 
ATOM 2104 C CD  . GLN C 3 19  ? 150.259 199.671 175.932 1.00 137.85 ? 13  GLN K CD  1 
ATOM 2105 O OE1 . GLN C 3 19  ? 149.798 199.001 175.007 1.00 137.85 ? 13  GLN K OE1 1 
ATOM 2106 N NE2 . GLN C 3 19  ? 150.202 200.998 175.955 1.00 137.85 ? 13  GLN K NE2 1 
ATOM 2107 N N   . PRO C 3 20  ? 149.672 195.473 179.108 1.00 133.49 ? 14  PRO K N   1 
ATOM 2108 C CA  . PRO C 3 20  ? 148.815 194.284 179.140 1.00 133.49 ? 14  PRO K CA  1 
ATOM 2109 C C   . PRO C 3 20  ? 148.410 193.919 177.725 1.00 133.49 ? 14  PRO K C   1 
ATOM 2110 O O   . PRO C 3 20  ? 147.834 194.731 176.999 1.00 133.49 ? 14  PRO K O   1 
ATOM 2111 C CB  . PRO C 3 20  ? 147.616 194.733 179.979 1.00 133.49 ? 14  PRO K CB  1 
ATOM 2112 C CG  . PRO C 3 20  ? 148.123 195.856 180.792 1.00 133.49 ? 14  PRO K CG  1 
ATOM 2113 C CD  . PRO C 3 20  ? 149.128 196.560 179.936 1.00 133.49 ? 14  PRO K CD  1 
ATOM 2114 N N   . GLY C 3 21  ? 148.716 192.688 177.331 1.00 128.20 ? 15  GLY K N   1 
ATOM 2115 C CA  . GLY C 3 21  ? 148.575 192.341 175.933 1.00 128.20 ? 15  GLY K CA  1 
ATOM 2116 C C   . GLY C 3 21  ? 149.223 191.015 175.596 1.00 128.20 ? 15  GLY K C   1 
ATOM 2117 O O   . GLY C 3 21  ? 149.397 190.148 176.451 1.00 128.20 ? 15  GLY K O   1 
ATOM 2118 N N   . GLY C 3 22  ? 149.578 190.895 174.318 1.00 125.62 ? 16  GLY K N   1 
ATOM 2119 C CA  . GLY C 3 22  ? 149.748 189.590 173.702 1.00 125.62 ? 16  GLY K CA  1 
ATOM 2120 C C   . GLY C 3 22  ? 150.929 188.772 174.194 1.00 125.62 ? 16  GLY K C   1 
ATOM 2121 O O   . GLY C 3 22  ? 150.819 187.552 174.328 1.00 125.62 ? 16  GLY K O   1 
ATOM 2122 N N   . SER C 3 23  ? 152.077 189.399 174.439 1.00 118.71 ? 17  SER K N   1 
ATOM 2123 C CA  . SER C 3 23  ? 153.262 188.553 174.473 1.00 118.71 ? 17  SER K CA  1 
ATOM 2124 C C   . SER C 3 23  ? 154.414 189.210 175.218 1.00 118.71 ? 17  SER K C   1 
ATOM 2125 O O   . SER C 3 23  ? 154.552 190.433 175.224 1.00 118.71 ? 17  SER K O   1 
ATOM 2126 C CB  . SER C 3 23  ? 153.694 188.204 173.043 1.00 118.71 ? 17  SER K CB  1 
ATOM 2127 O OG  . SER C 3 23  ? 154.988 187.631 173.015 1.00 118.71 ? 17  SER K OG  1 
ATOM 2128 N N   . LEU C 3 24  ? 155.213 188.363 175.874 1.00 115.04 ? 18  LEU K N   1 
ATOM 2129 C CA  . LEU C 3 24  ? 156.581 188.656 176.294 1.00 115.04 ? 18  LEU K CA  1 
ATOM 2130 C C   . LEU C 3 24  ? 157.260 187.319 176.563 1.00 115.04 ? 18  LEU K C   1 
ATOM 2131 O O   . LEU C 3 24  ? 156.693 186.467 177.253 1.00 115.04 ? 18  LEU K O   1 
ATOM 2132 C CB  . LEU C 3 24  ? 156.627 189.550 177.539 1.00 115.04 ? 18  LEU K CB  1 
ATOM 2133 C CG  . LEU C 3 24  ? 158.022 189.869 178.087 1.00 115.04 ? 18  LEU K CG  1 
ATOM 2134 C CD1 . LEU C 3 24  ? 158.970 190.269 176.973 1.00 115.04 ? 18  LEU K CD1 1 
ATOM 2135 C CD2 . LEU C 3 24  ? 157.948 190.971 179.132 1.00 115.04 ? 18  LEU K CD2 1 
ATOM 2136 N N   . ARG C 3 25  ? 158.448 187.116 176.007 1.00 115.58 ? 19  ARG K N   1 
ATOM 2137 C CA  . ARG C 3 25  ? 159.167 185.863 176.198 1.00 115.58 ? 19  ARG K CA  1 
ATOM 2138 C C   . ARG C 3 25  ? 160.380 186.079 177.091 1.00 115.58 ? 19  ARG K C   1 
ATOM 2139 O O   . ARG C 3 25  ? 161.134 187.040 176.906 1.00 115.58 ? 19  ARG K O   1 
ATOM 2140 C CB  . ARG C 3 25  ? 159.603 185.249 174.869 1.00 115.58 ? 19  ARG K CB  1 
ATOM 2141 C CG  . ARG C 3 25  ? 160.470 184.016 175.050 1.00 115.58 ? 19  ARG K CG  1 
ATOM 2142 C CD  . ARG C 3 25  ? 160.779 183.322 173.743 1.00 115.58 ? 19  ARG K CD  1 
ATOM 2143 N NE  . ARG C 3 25  ? 159.635 182.560 173.263 1.00 115.58 ? 19  ARG K NE  1 
ATOM 2144 C CZ  . ARG C 3 25  ? 159.698 181.623 172.328 1.00 115.58 ? 19  ARG K CZ  1 
ATOM 2145 N NH1 . ARG C 3 25  ? 160.841 181.306 171.744 1.00 115.58 ? 19  ARG K NH1 1 
ATOM 2146 N NH2 . ARG C 3 25  ? 158.587 180.983 171.975 1.00 115.58 ? 19  ARG K NH2 1 
ATOM 2147 N N   . LEU C 3 26  ? 160.554 185.183 178.058 1.00 113.87 ? 20  LEU K N   1 
ATOM 2148 C CA  . LEU C 3 26  ? 161.708 185.149 178.940 1.00 113.87 ? 20  LEU K CA  1 
ATOM 2149 C C   . LEU C 3 26  ? 162.527 183.902 178.644 1.00 113.87 ? 20  LEU K C   1 
ATOM 2150 O O   . LEU C 3 26  ? 161.985 182.868 178.246 1.00 113.87 ? 20  LEU K O   1 
ATOM 2151 C CB  . LEU C 3 26  ? 161.285 185.144 180.412 1.00 113.87 ? 20  LEU K CB  1 
ATOM 2152 C CG  . LEU C 3 26  ? 160.055 185.958 180.824 1.00 113.87 ? 20  LEU K CG  1 
ATOM 2153 C CD1 . LEU C 3 26  ? 159.819 185.832 182.314 1.00 113.87 ? 20  LEU K CD1 1 
ATOM 2154 C CD2 . LEU C 3 26  ? 160.209 187.414 180.439 1.00 113.87 ? 20  LEU K CD2 1 
ATOM 2155 N N   . SER C 3 27  ? 163.838 183.994 178.845 1.00 119.50 ? 21  SER K N   1 
ATOM 2156 C CA  . SER C 3 27  ? 164.714 182.885 178.509 1.00 119.50 ? 21  SER K CA  1 
ATOM 2157 C C   . SER C 3 27  ? 165.738 182.688 179.611 1.00 119.50 ? 21  SER K C   1 
ATOM 2158 O O   . SER C 3 27  ? 166.097 183.631 180.318 1.00 119.50 ? 21  SER K O   1 
ATOM 2159 C CB  . SER C 3 27  ? 165.435 183.123 177.178 1.00 119.50 ? 21  SER K CB  1 
ATOM 2160 O OG  . SER C 3 27  ? 166.469 184.081 177.331 1.00 119.50 ? 21  SER K OG  1 
ATOM 2161 N N   . CYS C 3 28  ? 166.211 181.454 179.748 1.00 127.96 ? 22  CYS K N   1 
ATOM 2162 C CA  . CYS C 3 28  ? 167.300 181.173 180.670 1.00 127.96 ? 22  CYS K CA  1 
ATOM 2163 C C   . CYS C 3 28  ? 168.095 179.993 180.136 1.00 127.96 ? 22  CYS K C   1 
ATOM 2164 O O   . CYS C 3 28  ? 167.601 179.198 179.340 1.00 127.96 ? 22  CYS K O   1 
ATOM 2165 C CB  . CYS C 3 28  ? 166.787 180.908 182.094 1.00 127.96 ? 22  CYS K CB  1 
ATOM 2166 S SG  . CYS C 3 28  ? 165.504 179.643 182.257 1.00 127.96 ? 22  CYS K SG  1 
ATOM 2167 N N   . ALA C 3 29  ? 169.341 179.889 180.587 1.00 135.53 ? 23  ALA K N   1 
ATOM 2168 C CA  . ALA C 3 29  ? 170.262 178.899 180.058 1.00 135.53 ? 23  ALA K CA  1 
ATOM 2169 C C   . ALA C 3 29  ? 171.207 178.435 181.155 1.00 135.53 ? 23  ALA K C   1 
ATOM 2170 O O   . ALA C 3 29  ? 171.587 179.208 182.042 1.00 135.53 ? 23  ALA K O   1 
ATOM 2171 C CB  . ALA C 3 29  ? 171.060 179.451 178.871 1.00 135.53 ? 23  ALA K CB  1 
ATOM 2172 N N   . ALA C 3 30  ? 171.579 177.162 181.079 1.00 139.53 ? 24  ALA K N   1 
ATOM 2173 C CA  . ALA C 3 30  ? 172.488 176.551 182.033 1.00 139.53 ? 24  ALA K CA  1 
ATOM 2174 C C   . ALA C 3 30  ? 173.916 176.594 181.510 1.00 139.53 ? 24  ALA K C   1 
ATOM 2175 O O   . ALA C 3 30  ? 174.163 176.510 180.305 1.00 139.53 ? 24  ALA K O   1 
ATOM 2176 C CB  . ALA C 3 30  ? 172.081 175.105 182.315 1.00 139.53 ? 24  ALA K CB  1 
ATOM 2177 N N   . SER C 3 31  ? 174.859 176.728 182.435 1.00 146.01 ? 25  SER K N   1 
ATOM 2178 C CA  . SER C 3 31  ? 176.276 176.743 182.098 1.00 146.01 ? 25  SER K CA  1 
ATOM 2179 C C   . SER C 3 31  ? 177.016 175.860 183.089 1.00 146.01 ? 25  SER K C   1 
ATOM 2180 O O   . SER C 3 31  ? 176.938 176.084 184.302 1.00 146.01 ? 25  SER K O   1 
ATOM 2181 C CB  . SER C 3 31  ? 176.835 178.167 182.116 1.00 146.01 ? 25  SER K CB  1 
ATOM 2182 O OG  . SER C 3 31  ? 178.204 178.182 181.754 1.00 146.01 ? 25  SER K OG  1 
ATOM 2183 N N   . GLY C 3 32  ? 177.739 174.870 182.566 1.00 145.38 ? 26  GLY K N   1 
ATOM 2184 C CA  . GLY C 3 32  ? 178.444 173.898 183.372 1.00 145.38 ? 26  GLY K CA  1 
ATOM 2185 C C   . GLY C 3 32  ? 177.741 172.564 183.521 1.00 145.38 ? 26  GLY K C   1 
ATOM 2186 O O   . GLY C 3 32  ? 178.371 171.601 183.973 1.00 145.38 ? 26  GLY K O   1 
ATOM 2187 N N   . ARG C 3 33  ? 176.463 172.478 183.155 1.00 145.26 ? 27  ARG K N   1 
ATOM 2188 C CA  . ARG C 3 33  ? 175.699 171.245 183.284 1.00 145.26 ? 27  ARG K CA  1 
ATOM 2189 C C   . ARG C 3 33  ? 174.639 171.196 182.195 1.00 145.26 ? 27  ARG K C   1 
ATOM 2190 O O   . ARG C 3 33  ? 173.930 172.181 181.977 1.00 145.26 ? 27  ARG K O   1 
ATOM 2191 C CB  . ARG C 3 33  ? 175.038 171.147 184.665 1.00 145.26 ? 27  ARG K CB  1 
ATOM 2192 C CG  . ARG C 3 33  ? 173.861 170.188 184.729 1.00 145.26 ? 27  ARG K CG  1 
ATOM 2193 C CD  . ARG C 3 33  ? 173.099 170.305 186.043 1.00 145.26 ? 27  ARG K CD  1 
ATOM 2194 N NE  . ARG C 3 33  ? 173.806 169.682 187.156 1.00 145.26 ? 27  ARG K NE  1 
ATOM 2195 C CZ  . ARG C 3 33  ? 173.294 169.507 188.368 1.00 145.26 ? 27  ARG K CZ  1 
ATOM 2196 N NH1 . ARG C 3 33  ? 172.064 169.897 188.663 1.00 145.26 ? 27  ARG K NH1 1 
ATOM 2197 N NH2 . ARG C 3 33  ? 174.034 168.924 189.307 1.00 145.26 ? 27  ARG K NH2 1 
ATOM 2198 N N   . THR C 3 34  ? 174.528 170.055 181.524 1.00 138.64 ? 28  THR K N   1 
ATOM 2199 C CA  . THR C 3 34  ? 173.455 169.860 180.565 1.00 138.64 ? 28  THR K CA  1 
ATOM 2200 C C   . THR C 3 34  ? 172.149 169.575 181.294 1.00 138.64 ? 28  THR K C   1 
ATOM 2201 O O   . THR C 3 34  ? 172.128 168.950 182.358 1.00 138.64 ? 28  THR K O   1 
ATOM 2202 C CB  . THR C 3 34  ? 173.779 168.714 179.608 1.00 138.64 ? 28  THR K CB  1 
ATOM 2203 O OG1 . THR C 3 34  ? 173.836 167.485 180.341 1.00 138.64 ? 28  THR K OG1 1 
ATOM 2204 C CG2 . THR C 3 34  ? 175.115 168.956 178.924 1.00 138.64 ? 28  THR K CG2 1 
ATOM 2205 N N   . ILE C 3 35  ? 171.050 170.033 180.704 1.00 129.46 ? 29  ILE K N   1 
ATOM 2206 C CA  . ILE C 3 35  ? 169.747 169.964 181.349 1.00 129.46 ? 29  ILE K CA  1 
ATOM 2207 C C   . ILE C 3 35  ? 168.777 169.067 180.587 1.00 129.46 ? 29  ILE K C   1 
ATOM 2208 O O   . ILE C 3 35  ? 167.571 169.170 180.776 1.00 129.46 ? 29  ILE K O   1 
ATOM 2209 C CB  . ILE C 3 35  ? 169.150 171.368 181.543 1.00 129.46 ? 29  ILE K CB  1 
ATOM 2210 C CG1 . ILE C 3 35  ? 168.983 172.075 180.198 1.00 129.46 ? 29  ILE K CG1 1 
ATOM 2211 C CG2 . ILE C 3 35  ? 170.028 172.184 182.465 1.00 129.46 ? 29  ILE K CG2 1 
ATOM 2212 C CD1 . ILE C 3 35  ? 168.359 173.446 180.310 1.00 129.46 ? 29  ILE K CD1 1 
ATOM 2213 N N   . SER C 3 36  ? 169.286 168.193 179.715 1.00 130.27 ? 30  SER K N   1 
ATOM 2214 C CA  . SER C 3 36  ? 168.406 167.233 179.059 1.00 130.27 ? 30  SER K CA  1 
ATOM 2215 C C   . SER C 3 36  ? 167.869 166.203 180.042 1.00 130.27 ? 30  SER K C   1 
ATOM 2216 O O   . SER C 3 36  ? 166.782 165.658 179.827 1.00 130.27 ? 30  SER K O   1 
ATOM 2217 C CB  . SER C 3 36  ? 169.133 166.538 177.910 1.00 130.27 ? 30  SER K CB  1 
ATOM 2218 O OG  . SER C 3 36  ? 170.312 165.892 178.358 1.00 130.27 ? 30  SER K OG  1 
ATOM 2219 N N   . ARG C 3 37  ? 168.600 165.939 181.127 1.00 128.11 ? 31  ARG K N   1 
ATOM 2220 C CA  . ARG C 3 37  ? 168.227 164.925 182.104 1.00 128.11 ? 31  ARG K CA  1 
ATOM 2221 C C   . ARG C 3 37  ? 167.716 165.521 183.409 1.00 128.11 ? 31  ARG K C   1 
ATOM 2222 O O   . ARG C 3 37  ? 167.546 164.786 184.388 1.00 128.11 ? 31  ARG K O   1 
ATOM 2223 C CB  . ARG C 3 37  ? 169.413 164.003 182.386 1.00 128.11 ? 31  ARG K CB  1 
ATOM 2224 C CG  . ARG C 3 37  ? 170.595 164.702 183.033 1.00 128.11 ? 31  ARG K CG  1 
ATOM 2225 C CD  . ARG C 3 37  ? 171.692 163.715 183.394 1.00 128.11 ? 31  ARG K CD  1 
ATOM 2226 N NE  . ARG C 3 37  ? 172.832 164.374 184.017 1.00 128.11 ? 31  ARG K NE  1 
ATOM 2227 C CZ  . ARG C 3 37  ? 173.901 164.804 183.360 1.00 128.11 ? 31  ARG K CZ  1 
ATOM 2228 N NH1 . ARG C 3 37  ? 174.017 164.649 182.052 1.00 128.11 ? 31  ARG K NH1 1 
ATOM 2229 N NH2 . ARG C 3 37  ? 174.879 165.403 184.034 1.00 128.11 ? 31  ARG K NH2 1 
ATOM 2230 N N   . TYR C 3 38  ? 167.478 166.829 183.453 1.00 122.68 ? 32  TYR K N   1 
ATOM 2231 C CA  . TYR C 3 38  ? 166.927 167.487 184.627 1.00 122.68 ? 32  TYR K CA  1 
ATOM 2232 C C   . TYR C 3 38  ? 165.719 168.316 184.226 1.00 122.68 ? 32  TYR K C   1 
ATOM 2233 O O   . TYR C 3 38  ? 165.617 168.789 183.091 1.00 122.68 ? 32  TYR K O   1 
ATOM 2234 C CB  . TYR C 3 38  ? 167.953 168.393 185.313 1.00 122.68 ? 32  TYR K CB  1 
ATOM 2235 C CG  . TYR C 3 38  ? 169.204 167.683 185.749 1.00 122.68 ? 32  TYR K CG  1 
ATOM 2236 C CD1 . TYR C 3 38  ? 169.183 166.787 186.806 1.00 122.68 ? 32  TYR K CD1 1 
ATOM 2237 C CD2 . TYR C 3 38  ? 170.411 167.917 185.112 1.00 122.68 ? 32  TYR K CD2 1 
ATOM 2238 C CE1 . TYR C 3 38  ? 170.330 166.136 187.212 1.00 122.68 ? 32  TYR K CE1 1 
ATOM 2239 C CE2 . TYR C 3 38  ? 171.562 167.272 185.509 1.00 122.68 ? 32  TYR K CE2 1 
ATOM 2240 C CZ  . TYR C 3 38  ? 171.517 166.384 186.560 1.00 122.68 ? 32  TYR K CZ  1 
ATOM 2241 O OH  . TYR C 3 38  ? 172.664 165.739 186.960 1.00 122.68 ? 32  TYR K OH  1 
ATOM 2242 N N   . ALA C 3 39  ? 164.798 168.479 185.165 1.00 112.88 ? 33  ALA K N   1 
ATOM 2243 C CA  . ALA C 3 39  ? 163.696 169.407 184.990 1.00 112.88 ? 33  ALA K CA  1 
ATOM 2244 C C   . ALA C 3 39  ? 164.119 170.809 185.414 1.00 112.88 ? 33  ALA K C   1 
ATOM 2245 O O   . ALA C 3 39  ? 164.999 170.988 186.261 1.00 112.88 ? 33  ALA K O   1 
ATOM 2246 C CB  . ALA C 3 39  ? 162.475 168.957 185.788 1.00 112.88 ? 33  ALA K CB  1 
ATOM 2247 N N   . MET C 3 40  ? 163.505 171.812 184.795 1.00 109.95 ? 34  MET K N   1 
ATOM 2248 C CA  . MET C 3 40  ? 163.767 173.196 185.157 1.00 109.95 ? 34  MET K CA  1 
ATOM 2249 C C   . MET C 3 40  ? 162.453 173.921 185.399 1.00 109.95 ? 34  MET K C   1 
ATOM 2250 O O   . MET C 3 40  ? 161.458 173.667 184.717 1.00 109.95 ? 34  MET K O   1 
ATOM 2251 C CB  . MET C 3 40  ? 164.595 173.904 184.079 1.00 109.95 ? 34  MET K CB  1 
ATOM 2252 C CG  . MET C 3 40  ? 166.048 173.456 184.044 1.00 109.95 ? 34  MET K CG  1 
ATOM 2253 S SD  . MET C 3 40  ? 167.160 174.722 183.413 1.00 109.95 ? 34  MET K SD  1 
ATOM 2254 C CE  . MET C 3 40  ? 166.847 176.046 184.575 1.00 109.95 ? 34  MET K CE  1 
ATOM 2255 N N   . SER C 3 41  ? 162.453 174.824 186.376 1.00 100.94 ? 35  SER K N   1 
ATOM 2256 C CA  . SER C 3 41  ? 161.241 175.502 186.799 1.00 100.94 ? 35  SER K CA  1 
ATOM 2257 C C   . SER C 3 41  ? 161.401 177.015 186.748 1.00 100.94 ? 35  SER K C   1 
ATOM 2258 O O   . SER C 3 41  ? 162.496 177.557 186.929 1.00 100.94 ? 35  SER K O   1 
ATOM 2259 C CB  . SER C 3 41  ? 160.833 175.071 188.214 1.00 100.94 ? 35  SER K CB  1 
ATOM 2260 O OG  . SER C 3 41  ? 160.594 173.675 188.278 1.00 100.94 ? 35  SER K OG  1 
ATOM 2261 N N   . TRP C 3 42  ? 160.275 177.677 186.490 1.00 102.42 ? 36  TRP K N   1 
ATOM 2262 C CA  . TRP C 3 42  ? 160.124 179.125 186.557 1.00 102.42 ? 36  TRP K CA  1 
ATOM 2263 C C   . TRP C 3 42  ? 159.359 179.485 187.818 1.00 102.42 ? 36  TRP K C   1 
ATOM 2264 O O   . TRP C 3 42  ? 158.320 178.885 188.111 1.00 102.42 ? 36  TRP K O   1 
ATOM 2265 C CB  . TRP C 3 42  ? 159.360 179.667 185.350 1.00 102.42 ? 36  TRP K CB  1 
ATOM 2266 C CG  . TRP C 3 42  ? 160.048 179.511 184.048 1.00 102.42 ? 36  TRP K CG  1 
ATOM 2267 C CD1 . TRP C 3 42  ? 160.017 178.423 183.234 1.00 102.42 ? 36  TRP K CD1 1 
ATOM 2268 C CD2 . TRP C 3 42  ? 160.864 180.483 183.390 1.00 102.42 ? 36  TRP K CD2 1 
ATOM 2269 N NE1 . TRP C 3 42  ? 160.770 178.650 182.114 1.00 102.42 ? 36  TRP K NE1 1 
ATOM 2270 C CE2 . TRP C 3 42  ? 161.303 179.909 182.186 1.00 102.42 ? 36  TRP K CE2 1 
ATOM 2271 C CE3 . TRP C 3 42  ? 161.272 181.782 183.707 1.00 102.42 ? 36  TRP K CE3 1 
ATOM 2272 C CZ2 . TRP C 3 42  ? 162.126 180.586 181.295 1.00 102.42 ? 36  TRP K CZ2 1 
ATOM 2273 C CZ3 . TRP C 3 42  ? 162.086 182.451 182.821 1.00 102.42 ? 36  TRP K CZ3 1 
ATOM 2274 C CH2 . TRP C 3 42  ? 162.506 181.854 181.630 1.00 102.42 ? 36  TRP K CH2 1 
ATOM 2275 N N   . PHE C 3 43  ? 159.873 180.480 188.540 1.00 101.56 ? 37  PHE K N   1 
ATOM 2276 C CA  . PHE C 3 43  ? 159.299 181.002 189.770 1.00 101.56 ? 37  PHE K CA  1 
ATOM 2277 C C   . PHE C 3 43  ? 159.164 182.516 189.662 1.00 101.56 ? 37  PHE K C   1 
ATOM 2278 O O   . PHE C 3 43  ? 159.935 183.175 188.965 1.00 101.56 ? 37  PHE K O   1 
ATOM 2279 C CB  . PHE C 3 43  ? 160.158 180.645 190.992 1.00 101.56 ? 37  PHE K CB  1 
ATOM 2280 C CG  . PHE C 3 43  ? 160.035 179.214 191.419 1.00 101.56 ? 37  PHE K CG  1 
ATOM 2281 C CD1 . PHE C 3 43  ? 160.820 178.237 190.842 1.00 101.56 ? 37  PHE K CD1 1 
ATOM 2282 C CD2 . PHE C 3 43  ? 159.126 178.846 192.390 1.00 101.56 ? 37  PHE K CD2 1 
ATOM 2283 C CE1 . PHE C 3 43  ? 160.707 176.925 191.231 1.00 101.56 ? 37  PHE K CE1 1 
ATOM 2284 C CE2 . PHE C 3 43  ? 159.005 177.534 192.778 1.00 101.56 ? 37  PHE K CE2 1 
ATOM 2285 C CZ  . PHE C 3 43  ? 159.799 176.573 192.200 1.00 101.56 ? 37  PHE K CZ  1 
ATOM 2286 N N   . ARG C 3 44  ? 158.185 183.061 190.377 1.00 108.91 ? 38  ARG K N   1 
ATOM 2287 C CA  . ARG C 3 44  ? 157.796 184.461 190.272 1.00 108.91 ? 38  ARG K CA  1 
ATOM 2288 C C   . ARG C 3 44  ? 157.747 185.072 191.659 1.00 108.91 ? 38  ARG K C   1 
ATOM 2289 O O   . ARG C 3 44  ? 157.044 184.563 192.531 1.00 108.91 ? 38  ARG K O   1 
ATOM 2290 C CB  . ARG C 3 44  ? 156.431 184.576 189.591 1.00 108.91 ? 38  ARG K CB  1 
ATOM 2291 C CG  . ARG C 3 44  ? 155.763 185.909 189.677 1.00 108.91 ? 38  ARG K CG  1 
ATOM 2292 C CD  . ARG C 3 44  ? 154.563 185.965 188.743 1.00 108.91 ? 38  ARG K CD  1 
ATOM 2293 N NE  . ARG C 3 44  ? 153.383 185.315 189.296 1.00 108.91 ? 38  ARG K NE  1 
ATOM 2294 C CZ  . ARG C 3 44  ? 152.226 185.197 188.660 1.00 108.91 ? 38  ARG K CZ  1 
ATOM 2295 N NH1 . ARG C 3 44  ? 152.071 185.628 187.420 1.00 108.91 ? 38  ARG K NH1 1 
ATOM 2296 N NH2 . ARG C 3 44  ? 151.197 184.638 189.285 1.00 108.91 ? 38  ARG K NH2 1 
ATOM 2297 N N   . GLN C 3 45  ? 158.466 186.170 191.864 1.00 116.18 ? 39  GLN K N   1 
ATOM 2298 C CA  . GLN C 3 45  ? 158.490 186.849 193.155 1.00 116.18 ? 39  GLN K CA  1 
ATOM 2299 C C   . GLN C 3 45  ? 158.057 188.293 192.942 1.00 116.18 ? 39  GLN K C   1 
ATOM 2300 O O   . GLN C 3 45  ? 158.801 189.094 192.364 1.00 116.18 ? 39  GLN K O   1 
ATOM 2301 C CB  . GLN C 3 45  ? 159.872 186.772 193.804 1.00 116.18 ? 39  GLN K CB  1 
ATOM 2302 C CG  . GLN C 3 45  ? 159.951 187.486 195.141 1.00 116.18 ? 39  GLN K CG  1 
ATOM 2303 C CD  . GLN C 3 45  ? 161.282 187.288 195.836 1.00 116.18 ? 39  GLN K CD  1 
ATOM 2304 O OE1 . GLN C 3 45  ? 162.251 186.838 195.228 1.00 116.18 ? 39  GLN K OE1 1 
ATOM 2305 N NE2 . GLN C 3 45  ? 161.335 187.620 197.121 1.00 116.18 ? 39  GLN K NE2 1 
ATOM 2306 N N   . ALA C 3 46  ? 156.834 188.600 193.358 1.00 125.24 ? 40  ALA K N   1 
ATOM 2307 C CA  . ALA C 3 46  ? 156.342 189.963 193.332 1.00 125.24 ? 40  ALA K CA  1 
ATOM 2308 C C   . ALA C 3 46  ? 156.986 190.770 194.458 1.00 125.24 ? 40  ALA K C   1 
ATOM 2309 O O   . ALA C 3 46  ? 157.416 190.205 195.466 1.00 125.24 ? 40  ALA K O   1 
ATOM 2310 C CB  . ALA C 3 46  ? 154.824 189.981 193.480 1.00 125.24 ? 40  ALA K CB  1 
ATOM 2311 N N   . PRO C 3 47  ? 157.089 192.089 194.300 1.00 128.97 ? 41  PRO K N   1 
ATOM 2312 C CA  . PRO C 3 47  ? 157.576 192.923 195.408 1.00 128.97 ? 41  PRO K CA  1 
ATOM 2313 C C   . PRO C 3 47  ? 156.687 192.774 196.636 1.00 128.97 ? 41  PRO K C   1 
ATOM 2314 O O   . PRO C 3 47  ? 155.461 192.863 196.552 1.00 128.97 ? 41  PRO K O   1 
ATOM 2315 C CB  . PRO C 3 47  ? 157.516 194.342 194.833 1.00 128.97 ? 41  PRO K CB  1 
ATOM 2316 C CG  . PRO C 3 47  ? 157.568 194.153 193.358 1.00 128.97 ? 41  PRO K CG  1 
ATOM 2317 C CD  . PRO C 3 47  ? 156.836 192.879 193.085 1.00 128.97 ? 41  PRO K CD  1 
ATOM 2318 N N   . GLY C 3 48  ? 157.320 192.547 197.785 1.00 129.76 ? 42  GLY K N   1 
ATOM 2319 C CA  . GLY C 3 48  ? 156.597 192.325 199.019 1.00 129.76 ? 42  GLY K CA  1 
ATOM 2320 C C   . GLY C 3 48  ? 156.086 190.916 199.232 1.00 129.76 ? 42  GLY K C   1 
ATOM 2321 O O   . GLY C 3 48  ? 155.426 190.665 200.247 1.00 129.76 ? 42  GLY K O   1 
ATOM 2322 N N   . LYS C 3 49  ? 156.361 189.992 198.314 1.00 128.24 ? 43  LYS K N   1 
ATOM 2323 C CA  . LYS C 3 49  ? 155.898 188.616 198.407 1.00 128.24 ? 43  LYS K CA  1 
ATOM 2324 C C   . LYS C 3 49  ? 157.075 187.650 198.357 1.00 128.24 ? 43  LYS K C   1 
ATOM 2325 O O   . LYS C 3 49  ? 158.209 188.019 198.040 1.00 128.24 ? 43  LYS K O   1 
ATOM 2326 C CB  . LYS C 3 49  ? 154.912 188.286 197.280 1.00 128.24 ? 43  LYS K CB  1 
ATOM 2327 C CG  . LYS C 3 49  ? 153.562 188.956 197.402 1.00 128.24 ? 43  LYS K CG  1 
ATOM 2328 C CD  . LYS C 3 49  ? 152.631 188.460 196.312 1.00 128.24 ? 43  LYS K CD  1 
ATOM 2329 C CE  . LYS C 3 49  ? 151.201 188.904 196.547 1.00 128.24 ? 43  LYS K CE  1 
ATOM 2330 N NZ  . LYS C 3 49  ? 150.274 188.302 195.549 1.00 128.24 ? 43  LYS K NZ  1 
ATOM 2331 N N   . GLU C 3 50  ? 156.785 186.393 198.683 1.00 122.09 ? 44  GLU K N   1 
ATOM 2332 C CA  . GLU C 3 50  ? 157.735 185.301 198.543 1.00 122.09 ? 44  GLU K CA  1 
ATOM 2333 C C   . GLU C 3 50  ? 157.615 184.674 197.158 1.00 122.09 ? 44  GLU K C   1 
ATOM 2334 O O   . GLU C 3 50  ? 156.646 184.893 196.429 1.00 122.09 ? 44  GLU K O   1 
ATOM 2335 C CB  . GLU C 3 50  ? 157.505 184.243 199.622 1.00 122.09 ? 44  GLU K CB  1 
ATOM 2336 C CG  . GLU C 3 50  ? 157.683 184.751 201.042 1.00 122.09 ? 44  GLU K CG  1 
ATOM 2337 C CD  . GLU C 3 50  ? 157.303 183.716 202.084 1.00 122.09 ? 44  GLU K CD  1 
ATOM 2338 O OE1 . GLU C 3 50  ? 156.749 182.661 201.705 1.00 122.09 ? 44  GLU K OE1 1 
ATOM 2339 O OE2 . GLU C 3 50  ? 157.559 183.959 203.283 1.00 122.09 ? 44  GLU K OE2 1 
ATOM 2340 N N   . ARG C 3 51  ? 158.619 183.878 196.800 1.00 114.88 ? 45  ARG K N   1 
ATOM 2341 C CA  . ARG C 3 51  ? 158.649 183.262 195.481 1.00 114.88 ? 45  ARG K CA  1 
ATOM 2342 C C   . ARG C 3 51  ? 157.498 182.277 195.320 1.00 114.88 ? 45  ARG K C   1 
ATOM 2343 O O   . ARG C 3 51  ? 157.301 181.390 196.155 1.00 114.88 ? 45  ARG K O   1 
ATOM 2344 C CB  . ARG C 3 51  ? 159.984 182.558 195.251 1.00 114.88 ? 45  ARG K CB  1 
ATOM 2345 C CG  . ARG C 3 51  ? 161.181 183.487 195.239 1.00 114.88 ? 45  ARG K CG  1 
ATOM 2346 C CD  . ARG C 3 51  ? 162.460 182.736 194.924 1.00 114.88 ? 45  ARG K CD  1 
ATOM 2347 N NE  . ARG C 3 51  ? 163.626 183.611 194.935 1.00 114.88 ? 45  ARG K NE  1 
ATOM 2348 C CZ  . ARG C 3 51  ? 164.882 183.185 194.916 1.00 114.88 ? 45  ARG K CZ  1 
ATOM 2349 N NH1 . ARG C 3 51  ? 165.174 181.895 194.893 1.00 114.88 ? 45  ARG K NH1 1 
ATOM 2350 N NH2 . ARG C 3 51  ? 165.870 184.075 194.925 1.00 114.88 ? 45  ARG K NH2 1 
ATOM 2351 N N   . GLU C 3 52  ? 156.744 182.432 194.246 1.00 107.01 ? 46  GLU K N   1 
ATOM 2352 C CA  . GLU C 3 52  ? 155.658 181.538 193.891 1.00 107.01 ? 46  GLU K CA  1 
ATOM 2353 C C   . GLU C 3 52  ? 156.103 180.639 192.749 1.00 107.01 ? 46  GLU K C   1 
ATOM 2354 O O   . GLU C 3 52  ? 156.922 181.028 191.917 1.00 107.01 ? 46  GLU K O   1 
ATOM 2355 C CB  . GLU C 3 52  ? 154.408 182.309 193.465 1.00 107.01 ? 46  GLU K CB  1 
ATOM 2356 C CG  . GLU C 3 52  ? 154.013 183.458 194.365 1.00 107.01 ? 46  GLU K CG  1 
ATOM 2357 C CD  . GLU C 3 52  ? 152.951 184.331 193.727 1.00 107.01 ? 46  GLU K CD  1 
ATOM 2358 O OE1 . GLU C 3 52  ? 152.689 184.150 192.519 1.00 107.01 ? 46  GLU K OE1 1 
ATOM 2359 O OE2 . GLU C 3 52  ? 152.381 185.193 194.430 1.00 107.01 ? 46  GLU K OE2 1 
ATOM 2360 N N   . PHE C 3 53  ? 155.561 179.428 192.716 1.00 85.80  ? 47  PHE K N   1 
ATOM 2361 C CA  . PHE C 3 53  ? 155.818 178.546 191.589 1.00 85.80  ? 47  PHE K CA  1 
ATOM 2362 C C   . PHE C 3 53  ? 155.059 179.024 190.360 1.00 85.80  ? 47  PHE K C   1 
ATOM 2363 O O   . PHE C 3 53  ? 153.901 179.442 190.448 1.00 85.80  ? 47  PHE K O   1 
ATOM 2364 C CB  . PHE C 3 53  ? 155.419 177.113 191.927 1.00 85.80  ? 47  PHE K CB  1 
ATOM 2365 C CG  . PHE C 3 53  ? 155.757 176.132 190.852 1.00 85.80  ? 47  PHE K CG  1 
ATOM 2366 C CD1 . PHE C 3 53  ? 157.059 175.712 190.676 1.00 85.80  ? 47  PHE K CD1 1 
ATOM 2367 C CD2 . PHE C 3 53  ? 154.778 175.637 190.011 1.00 85.80  ? 47  PHE K CD2 1 
ATOM 2368 C CE1 . PHE C 3 53  ? 157.381 174.821 189.695 1.00 85.80  ? 47  PHE K CE1 1 
ATOM 2369 C CE2 . PHE C 3 53  ? 155.096 174.741 189.025 1.00 85.80  ? 47  PHE K CE2 1 
ATOM 2370 C CZ  . PHE C 3 53  ? 156.399 174.332 188.870 1.00 85.80  ? 47  PHE K CZ  1 
ATOM 2371 N N   . VAL C 3 54  ? 155.716 178.968 189.202 1.00 88.58  ? 48  VAL K N   1 
ATOM 2372 C CA  . VAL C 3 54  ? 155.099 179.285 187.923 1.00 88.58  ? 48  VAL K CA  1 
ATOM 2373 C C   . VAL C 3 54  ? 154.980 178.043 187.053 1.00 88.58  ? 48  VAL K C   1 
ATOM 2374 O O   . VAL C 3 54  ? 153.878 177.655 186.667 1.00 88.58  ? 48  VAL K O   1 
ATOM 2375 C CB  . VAL C 3 54  ? 155.869 180.406 187.189 1.00 88.58  ? 48  VAL K CB  1 
ATOM 2376 C CG1 . VAL C 3 54  ? 155.030 180.961 186.050 1.00 88.58  ? 48  VAL K CG1 1 
ATOM 2377 C CG2 . VAL C 3 54  ? 156.228 181.490 188.146 1.00 88.58  ? 48  VAL K CG2 1 
ATOM 2378 N N   . ALA C 3 55  ? 156.100 177.400 186.737 1.00 87.09  ? 49  ALA K N   1 
ATOM 2379 C CA  . ALA C 3 55  ? 156.019 176.287 185.802 1.00 87.09  ? 49  ALA K CA  1 
ATOM 2380 C C   . ALA C 3 55  ? 157.228 175.377 185.945 1.00 87.09  ? 49  ALA K C   1 
ATOM 2381 O O   . ALA C 3 55  ? 158.267 175.772 186.469 1.00 87.09  ? 49  ALA K O   1 
ATOM 2382 C CB  . ALA C 3 55  ? 155.902 176.788 184.364 1.00 87.09  ? 49  ALA K CB  1 
ATOM 2383 N N   . VAL C 3 56  ? 157.063 174.140 185.492 1.00 91.01  ? 50  VAL K N   1 
ATOM 2384 C CA  . VAL C 3 56  ? 158.146 173.164 185.476 1.00 91.01  ? 50  VAL K CA  1 
ATOM 2385 C C   . VAL C 3 56  ? 158.097 172.407 184.155 1.00 91.01  ? 50  VAL K C   1 
ATOM 2386 O O   . VAL C 3 56  ? 157.023 171.995 183.703 1.00 91.01  ? 50  VAL K O   1 
ATOM 2387 C CB  . VAL C 3 56  ? 158.075 172.198 186.678 1.00 91.01  ? 50  VAL K CB  1 
ATOM 2388 C CG1 . VAL C 3 56  ? 156.735 171.483 186.730 1.00 91.01  ? 50  VAL K CG1 1 
ATOM 2389 C CG2 . VAL C 3 56  ? 159.212 171.202 186.634 1.00 91.01  ? 50  VAL K CG2 1 
ATOM 2390 N N   . ALA C 3 57  ? 159.256 172.249 183.529 1.00 99.41  ? 51  ALA K N   1 
ATOM 2391 C CA  . ALA C 3 57  ? 159.412 171.419 182.344 1.00 99.41  ? 51  ALA K CA  1 
ATOM 2392 C C   . ALA C 3 57  ? 160.344 170.265 182.675 1.00 99.41  ? 51  ALA K C   1 
ATOM 2393 O O   . ALA C 3 57  ? 161.453 170.482 183.173 1.00 99.41  ? 51  ALA K O   1 
ATOM 2394 C CB  . ALA C 3 57  ? 159.961 172.229 181.169 1.00 99.41  ? 51  ALA K CB  1 
ATOM 2395 N N   . ARG C 3 58  ? 159.894 169.046 182.393 1.00 100.59 ? 52  ARG K N   1 
ATOM 2396 C CA  . ARG C 3 58  ? 160.635 167.840 182.714 1.00 100.59 ? 52  ARG K CA  1 
ATOM 2397 C C   . ARG C 3 58  ? 161.310 167.283 181.458 1.00 100.59 ? 52  ARG K C   1 
ATOM 2398 O O   . ARG C 3 58  ? 161.249 167.869 180.375 1.00 100.59 ? 52  ARG K O   1 
ATOM 2399 C CB  . ARG C 3 58  ? 159.707 166.822 183.373 1.00 100.59 ? 52  ARG K CB  1 
ATOM 2400 C CG  . ARG C 3 58  ? 159.209 167.273 184.737 1.00 100.59 ? 52  ARG K CG  1 
ATOM 2401 C CD  . ARG C 3 58  ? 158.040 166.433 185.202 1.00 100.59 ? 52  ARG K CD  1 
ATOM 2402 N NE  . ARG C 3 58  ? 157.589 166.801 186.538 1.00 100.59 ? 52  ARG K NE  1 
ATOM 2403 C CZ  . ARG C 3 58  ? 156.737 166.084 187.258 1.00 100.59 ? 52  ARG K CZ  1 
ATOM 2404 N NH1 . ARG C 3 58  ? 156.231 164.951 186.803 1.00 100.59 ? 52  ARG K NH1 1 
ATOM 2405 N NH2 . ARG C 3 58  ? 156.387 166.513 188.467 1.00 100.59 ? 52  ARG K NH2 1 
ATOM 2406 N N   . ARG C 3 59  ? 161.958 166.126 181.617 1.00 113.30 ? 53  ARG K N   1 
ATOM 2407 C CA  . ARG C 3 59  ? 162.951 165.633 180.665 1.00 113.30 ? 53  ARG K CA  1 
ATOM 2408 C C   . ARG C 3 59  ? 162.412 165.343 179.266 1.00 113.30 ? 53  ARG K C   1 
ATOM 2409 O O   . ARG C 3 59  ? 162.806 166.004 178.300 1.00 113.30 ? 53  ARG K O   1 
ATOM 2410 C CB  . ARG C 3 59  ? 163.613 164.371 181.220 1.00 113.30 ? 53  ARG K CB  1 
ATOM 2411 C CG  . ARG C 3 59  ? 164.537 164.613 182.402 1.00 113.30 ? 53  ARG K CG  1 
ATOM 2412 C CD  . ARG C 3 59  ? 165.092 163.300 182.931 1.00 113.30 ? 53  ARG K CD  1 
ATOM 2413 N NE  . ARG C 3 59  ? 164.036 162.467 183.492 1.00 113.30 ? 53  ARG K NE  1 
ATOM 2414 C CZ  . ARG C 3 59  ? 164.213 161.242 183.966 1.00 113.30 ? 53  ARG K CZ  1 
ATOM 2415 N NH1 . ARG C 3 59  ? 165.402 160.662 183.956 1.00 113.30 ? 53  ARG K NH1 1 
ATOM 2416 N NH2 . ARG C 3 59  ? 163.170 160.582 184.460 1.00 113.30 ? 53  ARG K NH2 1 
ATOM 2417 N N   . SER C 3 60  ? 161.531 164.354 179.137 1.00 114.46 ? 54  SER K N   1 
ATOM 2418 C CA  . SER C 3 60  ? 161.110 163.896 177.813 1.00 114.46 ? 54  SER K CA  1 
ATOM 2419 C C   . SER C 3 60  ? 159.814 163.115 177.942 1.00 114.46 ? 54  SER K C   1 
ATOM 2420 O O   . SER C 3 60  ? 159.785 162.070 178.600 1.00 114.46 ? 54  SER K O   1 
ATOM 2421 C CB  . SER C 3 60  ? 162.198 163.032 177.170 1.00 114.46 ? 54  SER K CB  1 
ATOM 2422 O OG  . SER C 3 60  ? 161.749 162.455 175.956 1.00 114.46 ? 54  SER K OG  1 
ATOM 2423 N N   . GLY C 3 61  ? 158.748 163.614 177.320 1.00 118.97 ? 55  GLY K N   1 
ATOM 2424 C CA  . GLY C 3 61  ? 157.467 162.943 177.344 1.00 118.97 ? 55  GLY K CA  1 
ATOM 2425 C C   . GLY C 3 61  ? 156.700 163.097 178.633 1.00 118.97 ? 55  GLY K C   1 
ATOM 2426 O O   . GLY C 3 61  ? 155.544 162.660 178.707 1.00 118.97 ? 55  GLY K O   1 
ATOM 2427 N N   . ASP C 3 62  ? 157.299 163.718 179.647 1.00 112.64 ? 56  ASP K N   1 
ATOM 2428 C CA  . ASP C 3 62  ? 156.631 163.999 180.907 1.00 112.64 ? 56  ASP K CA  1 
ATOM 2429 C C   . ASP C 3 62  ? 155.782 165.259 180.840 1.00 112.64 ? 56  ASP K C   1 
ATOM 2430 O O   . ASP C 3 62  ? 154.967 165.490 181.740 1.00 112.64 ? 56  ASP K O   1 
ATOM 2431 C CB  . ASP C 3 62  ? 157.675 164.132 182.016 1.00 112.64 ? 56  ASP K CB  1 
ATOM 2432 C CG  . ASP C 3 62  ? 158.699 163.017 181.982 1.00 112.64 ? 56  ASP K CG  1 
ATOM 2433 O OD1 . ASP C 3 62  ? 158.304 161.842 182.138 1.00 112.64 ? 56  ASP K OD1 1 
ATOM 2434 O OD2 . ASP C 3 62  ? 159.893 163.311 181.773 1.00 112.64 ? 56  ASP K OD2 1 
ATOM 2435 N N   . GLY C 3 63  ? 155.958 166.065 179.798 1.00 100.19 ? 57  GLY K N   1 
ATOM 2436 C CA  . GLY C 3 63  ? 155.211 167.292 179.634 1.00 100.19 ? 57  GLY K CA  1 
ATOM 2437 C C   . GLY C 3 63  ? 155.712 168.390 180.555 1.00 100.19 ? 57  GLY K C   1 
ATOM 2438 O O   . GLY C 3 63  ? 156.832 168.359 181.071 1.00 100.19 ? 57  GLY K O   1 
ATOM 2439 N N   . ALA C 3 64  ? 154.850 169.377 180.765 1.00 89.35  ? 58  ALA K N   1 
ATOM 2440 C CA  . ALA C 3 64  ? 155.179 170.507 181.616 1.00 89.35  ? 58  ALA K CA  1 
ATOM 2441 C C   . ALA C 3 64  ? 153.946 170.877 182.418 1.00 89.35  ? 58  ALA K C   1 
ATOM 2442 O O   . ALA C 3 64  ? 152.816 170.648 181.985 1.00 89.35  ? 58  ALA K O   1 
ATOM 2443 C CB  . ALA C 3 64  ? 155.671 171.706 180.801 1.00 89.35  ? 58  ALA K CB  1 
ATOM 2444 N N   . PHE C 3 65  ? 154.173 171.456 183.590 1.00 84.77  ? 59  PHE K N   1 
ATOM 2445 C CA  . PHE C 3 65  ? 153.101 171.756 184.524 1.00 84.77  ? 59  PHE K CA  1 
ATOM 2446 C C   . PHE C 3 65  ? 153.158 173.226 184.912 1.00 84.77  ? 59  PHE K C   1 
ATOM 2447 O O   . PHE C 3 65  ? 154.236 173.820 184.988 1.00 84.77  ? 59  PHE K O   1 
ATOM 2448 C CB  . PHE C 3 65  ? 153.193 170.857 185.765 1.00 84.77  ? 59  PHE K CB  1 
ATOM 2449 C CG  . PHE C 3 65  ? 153.215 169.386 185.444 1.00 84.77  ? 59  PHE K CG  1 
ATOM 2450 C CD1 . PHE C 3 65  ? 152.034 168.688 185.241 1.00 84.77  ? 59  PHE K CD1 1 
ATOM 2451 C CD2 . PHE C 3 65  ? 154.416 168.706 185.332 1.00 84.77  ? 59  PHE K CD2 1 
ATOM 2452 C CE1 . PHE C 3 65  ? 152.051 167.342 184.939 1.00 84.77  ? 59  PHE K CE1 1 
ATOM 2453 C CE2 . PHE C 3 65  ? 154.439 167.358 185.029 1.00 84.77  ? 59  PHE K CE2 1 
ATOM 2454 C CZ  . PHE C 3 65  ? 153.254 166.676 184.835 1.00 84.77  ? 59  PHE K CZ  1 
ATOM 2455 N N   . TYR C 3 66  ? 151.985 173.811 185.154 1.00 81.52  ? 60  TYR K N   1 
ATOM 2456 C CA  . TYR C 3 66  ? 151.862 175.242 185.388 1.00 81.52  ? 60  TYR K CA  1 
ATOM 2457 C C   . TYR C 3 66  ? 151.023 175.519 186.629 1.00 81.52  ? 60  TYR K C   1 
ATOM 2458 O O   . TYR C 3 66  ? 150.101 174.769 186.955 1.00 81.52  ? 60  TYR K O   1 
ATOM 2459 C CB  . TYR C 3 66  ? 151.233 175.946 184.179 1.00 81.52  ? 60  TYR K CB  1 
ATOM 2460 C CG  . TYR C 3 66  ? 151.901 175.611 182.869 1.00 81.52  ? 60  TYR K CG  1 
ATOM 2461 C CD1 . TYR C 3 66  ? 153.123 176.169 182.533 1.00 81.52  ? 60  TYR K CD1 1 
ATOM 2462 C CD2 . TYR C 3 66  ? 151.314 174.733 181.971 1.00 81.52  ? 60  TYR K CD2 1 
ATOM 2463 C CE1 . TYR C 3 66  ? 153.746 175.864 181.341 1.00 81.52  ? 60  TYR K CE1 1 
ATOM 2464 C CE2 . TYR C 3 66  ? 151.927 174.424 180.772 1.00 81.52  ? 60  TYR K CE2 1 
ATOM 2465 C CZ  . TYR C 3 66  ? 153.145 174.992 180.463 1.00 81.52  ? 60  TYR K CZ  1 
ATOM 2466 O OH  . TYR C 3 66  ? 153.765 174.692 179.272 1.00 81.52  ? 60  TYR K OH  1 
ATOM 2467 N N   . ALA C 3 67  ? 151.344 176.620 187.305 1.00 84.57  ? 61  ALA K N   1 
ATOM 2468 C CA  . ALA C 3 67  ? 150.580 177.060 188.462 1.00 84.57  ? 61  ALA K CA  1 
ATOM 2469 C C   . ALA C 3 67  ? 149.205 177.557 188.034 1.00 84.57  ? 61  ALA K C   1 
ATOM 2470 O O   . ALA C 3 67  ? 148.952 177.818 186.860 1.00 84.57  ? 61  ALA K O   1 
ATOM 2471 C CB  . ALA C 3 67  ? 151.321 178.164 189.208 1.00 84.57  ? 61  ALA K CB  1 
ATOM 2472 N N   . ASP C 3 68  ? 148.303 177.668 189.012 1.00 97.73  ? 62  ASP K N   1 
ATOM 2473 C CA  . ASP C 3 68  ? 146.950 178.139 188.727 1.00 97.73  ? 62  ASP K CA  1 
ATOM 2474 C C   . ASP C 3 68  ? 146.956 179.511 188.064 1.00 97.73  ? 62  ASP K C   1 
ATOM 2475 O O   . ASP C 3 68  ? 146.112 179.796 187.209 1.00 97.73  ? 62  ASP K O   1 
ATOM 2476 C CB  . ASP C 3 68  ? 146.125 178.188 190.011 1.00 97.73  ? 62  ASP K CB  1 
ATOM 2477 C CG  . ASP C 3 68  ? 145.734 176.816 190.508 1.00 97.73  ? 62  ASP K CG  1 
ATOM 2478 O OD1 . ASP C 3 68  ? 145.337 175.973 189.678 1.00 97.73  ? 62  ASP K OD1 1 
ATOM 2479 O OD2 . ASP C 3 68  ? 145.822 176.579 191.732 1.00 97.73  ? 62  ASP K OD2 1 
ATOM 2480 N N   . SER C 3 69  ? 147.896 180.378 188.448 1.00 96.26  ? 63  SER K N   1 
ATOM 2481 C CA  . SER C 3 69  ? 147.907 181.745 187.944 1.00 96.26  ? 63  SER K CA  1 
ATOM 2482 C C   . SER C 3 69  ? 148.355 181.844 186.491 1.00 96.26  ? 63  SER K C   1 
ATOM 2483 O O   . SER C 3 69  ? 148.015 182.820 185.818 1.00 96.26  ? 63  SER K O   1 
ATOM 2484 C CB  . SER C 3 69  ? 148.815 182.607 188.814 1.00 96.26  ? 63  SER K CB  1 
ATOM 2485 O OG  . SER C 3 69  ? 150.155 182.157 188.722 1.00 96.26  ? 63  SER K OG  1 
ATOM 2486 N N   . VAL C 3 70  ? 149.110 180.876 185.988 1.00 93.31  ? 64  VAL K N   1 
ATOM 2487 C CA  . VAL C 3 70  ? 149.707 180.973 184.667 1.00 93.31  ? 64  VAL K CA  1 
ATOM 2488 C C   . VAL C 3 70  ? 149.271 179.828 183.780 1.00 93.31  ? 64  VAL K C   1 
ATOM 2489 O O   . VAL C 3 70  ? 149.625 179.791 182.594 1.00 93.31  ? 64  VAL K O   1 
ATOM 2490 C CB  . VAL C 3 70  ? 151.247 181.043 184.760 1.00 93.31  ? 64  VAL K CB  1 
ATOM 2491 C CG1 . VAL C 3 70  ? 151.675 182.045 185.818 1.00 93.31  ? 64  VAL K CG1 1 
ATOM 2492 C CG2 . VAL C 3 70  ? 151.809 179.669 185.053 1.00 93.31  ? 64  VAL K CG2 1 
ATOM 2493 N N   . GLN C 3 71  ? 148.523 178.885 184.332 1.00 97.94  ? 65  GLN K N   1 
ATOM 2494 C CA  . GLN C 3 71  ? 148.016 177.769 183.557 1.00 97.94  ? 65  GLN K CA  1 
ATOM 2495 C C   . GLN C 3 71  ? 147.135 178.271 182.422 1.00 97.94  ? 65  GLN K C   1 
ATOM 2496 O O   . GLN C 3 71  ? 146.227 179.081 182.631 1.00 97.94  ? 65  GLN K O   1 
ATOM 2497 C CB  . GLN C 3 71  ? 147.230 176.813 184.454 1.00 97.94  ? 65  GLN K CB  1 
ATOM 2498 C CG  . GLN C 3 71  ? 146.654 175.621 183.716 1.00 97.94  ? 65  GLN K CG  1 
ATOM 2499 C CD  . GLN C 3 71  ? 147.726 174.695 183.179 1.00 97.94  ? 65  GLN K CD  1 
ATOM 2500 O OE1 . GLN C 3 71  ? 148.574 174.209 183.928 1.00 97.94  ? 65  GLN K OE1 1 
ATOM 2501 N NE2 . GLN C 3 71  ? 147.695 174.443 181.875 1.00 97.94  ? 65  GLN K NE2 1 
ATOM 2502 N N   . GLY C 3 72  ? 147.413 177.793 181.211 1.00 106.29 ? 66  GLY K N   1 
ATOM 2503 C CA  . GLY C 3 72  ? 146.656 178.191 180.047 1.00 106.29 ? 66  GLY K CA  1 
ATOM 2504 C C   . GLY C 3 72  ? 147.025 179.544 179.490 1.00 106.29 ? 66  GLY K C   1 
ATOM 2505 O O   . GLY C 3 72  ? 146.446 179.958 178.478 1.00 106.29 ? 66  GLY K O   1 
ATOM 2506 N N   . ARG C 3 73  ? 147.965 180.242 180.113 1.00 108.85 ? 67  ARG K N   1 
ATOM 2507 C CA  . ARG C 3 73  ? 148.391 181.569 179.698 1.00 108.85 ? 67  ARG K CA  1 
ATOM 2508 C C   . ARG C 3 73  ? 149.869 181.620 179.351 1.00 108.85 ? 67  ARG K C   1 
ATOM 2509 O O   . ARG C 3 73  ? 150.248 182.230 178.346 1.00 108.85 ? 67  ARG K O   1 
ATOM 2510 C CB  . ARG C 3 73  ? 148.080 182.580 180.817 1.00 108.85 ? 67  ARG K CB  1 
ATOM 2511 C CG  . ARG C 3 73  ? 147.814 183.992 180.336 1.00 108.85 ? 67  ARG K CG  1 
ATOM 2512 C CD  . ARG C 3 73  ? 147.465 184.918 181.493 1.00 108.85 ? 67  ARG K CD  1 
ATOM 2513 N NE  . ARG C 3 73  ? 148.483 184.882 182.535 1.00 108.85 ? 67  ARG K NE  1 
ATOM 2514 C CZ  . ARG C 3 73  ? 148.532 185.708 183.570 1.00 108.85 ? 67  ARG K CZ  1 
ATOM 2515 N NH1 . ARG C 3 73  ? 147.638 186.669 183.732 1.00 108.85 ? 67  ARG K NH1 1 
ATOM 2516 N NH2 . ARG C 3 73  ? 149.506 185.571 184.463 1.00 108.85 ? 67  ARG K NH2 1 
ATOM 2517 N N   . PHE C 3 74  ? 150.713 180.989 180.157 1.00 102.41 ? 68  PHE K N   1 
ATOM 2518 C CA  . PHE C 3 74  ? 152.142 180.908 179.916 1.00 102.41 ? 68  PHE K CA  1 
ATOM 2519 C C   . PHE C 3 74  ? 152.481 179.492 179.472 1.00 102.41 ? 68  PHE K C   1 
ATOM 2520 O O   . PHE C 3 74  ? 151.862 178.527 179.920 1.00 102.41 ? 68  PHE K O   1 
ATOM 2521 C CB  . PHE C 3 74  ? 152.958 181.243 181.173 1.00 102.41 ? 68  PHE K CB  1 
ATOM 2522 C CG  . PHE C 3 74  ? 152.760 182.644 181.705 1.00 102.41 ? 68  PHE K CG  1 
ATOM 2523 C CD1 . PHE C 3 74  ? 151.704 183.443 181.289 1.00 102.41 ? 68  PHE K CD1 1 
ATOM 2524 C CD2 . PHE C 3 74  ? 153.650 183.157 182.633 1.00 102.41 ? 68  PHE K CD2 1 
ATOM 2525 C CE1 . PHE C 3 74  ? 151.539 184.713 181.791 1.00 102.41 ? 68  PHE K CE1 1 
ATOM 2526 C CE2 . PHE C 3 74  ? 153.493 184.430 183.137 1.00 102.41 ? 68  PHE K CE2 1 
ATOM 2527 C CZ  . PHE C 3 74  ? 152.437 185.210 182.716 1.00 102.41 ? 68  PHE K CZ  1 
ATOM 2528 N N   . THR C 3 75  ? 153.468 179.370 178.589 1.00 100.18 ? 69  THR K N   1 
ATOM 2529 C CA  . THR C 3 75  ? 153.953 178.066 178.157 1.00 100.18 ? 69  THR K CA  1 
ATOM 2530 C C   . THR C 3 75  ? 155.461 177.991 178.347 1.00 100.18 ? 69  THR K C   1 
ATOM 2531 O O   . THR C 3 75  ? 156.161 179.000 178.289 1.00 100.18 ? 69  THR K O   1 
ATOM 2532 C CB  . THR C 3 75  ? 153.600 177.772 176.697 1.00 100.18 ? 69  THR K CB  1 
ATOM 2533 O OG1 . THR C 3 75  ? 154.057 178.848 175.868 1.00 100.18 ? 69  THR K OG1 1 
ATOM 2534 C CG2 . THR C 3 75  ? 152.095 177.603 176.537 1.00 100.18 ? 69  THR K CG2 1 
ATOM 2535 N N   . VAL C 3 76  ? 155.956 176.784 178.588 1.00 99.50  ? 70  VAL K N   1 
ATOM 2536 C CA  . VAL C 3 76  ? 157.373 176.560 178.836 1.00 99.50  ? 70  VAL K CA  1 
ATOM 2537 C C   . VAL C 3 76  ? 157.894 175.538 177.837 1.00 99.50  ? 70  VAL K C   1 
ATOM 2538 O O   . VAL C 3 76  ? 157.256 174.509 177.591 1.00 99.50  ? 70  VAL K O   1 
ATOM 2539 C CB  . VAL C 3 76  ? 157.631 176.095 180.283 1.00 99.50  ? 70  VAL K CB  1 
ATOM 2540 C CG1 . VAL C 3 76  ? 159.095 175.750 180.481 1.00 99.50  ? 70  VAL K CG1 1 
ATOM 2541 C CG2 . VAL C 3 76  ? 157.229 177.178 181.240 1.00 99.50  ? 70  VAL K CG2 1 
ATOM 2542 N N   . SER C 3 77  ? 159.055 175.830 177.263 1.00 112.82 ? 71  SER K N   1 
ATOM 2543 C CA  . SER C 3 77  ? 159.700 174.935 176.316 1.00 112.82 ? 71  SER K CA  1 
ATOM 2544 C C   . SER C 3 77  ? 161.175 174.839 176.664 1.00 112.82 ? 71  SER K C   1 
ATOM 2545 O O   . SER C 3 77  ? 161.708 175.658 177.413 1.00 112.82 ? 71  SER K O   1 
ATOM 2546 C CB  . SER C 3 77  ? 159.519 175.415 174.869 1.00 112.82 ? 71  SER K CB  1 
ATOM 2547 O OG  . SER C 3 77  ? 160.006 176.737 174.705 1.00 112.82 ? 71  SER K OG  1 
ATOM 2548 N N   . ARG C 3 78  ? 161.834 173.817 176.127 1.00 120.85 ? 72  ARG K N   1 
ATOM 2549 C CA  . ARG C 3 78  ? 163.255 173.640 176.376 1.00 120.85 ? 72  ARG K CA  1 
ATOM 2550 C C   . ARG C 3 78  ? 163.957 173.182 175.109 1.00 120.85 ? 72  ARG K C   1 
ATOM 2551 O O   . ARG C 3 78  ? 163.451 172.327 174.376 1.00 120.85 ? 72  ARG K O   1 
ATOM 2552 C CB  . ARG C 3 78  ? 163.511 172.637 177.508 1.00 120.85 ? 72  ARG K CB  1 
ATOM 2553 C CG  . ARG C 3 78  ? 164.970 172.562 177.929 1.00 120.85 ? 72  ARG K CG  1 
ATOM 2554 C CD  . ARG C 3 78  ? 165.143 171.874 179.273 1.00 120.85 ? 72  ARG K CD  1 
ATOM 2555 N NE  . ARG C 3 78  ? 164.970 170.431 179.185 1.00 120.85 ? 72  ARG K NE  1 
ATOM 2556 C CZ  . ARG C 3 78  ? 163.842 169.792 179.461 1.00 120.85 ? 72  ARG K CZ  1 
ATOM 2557 N NH1 . ARG C 3 78  ? 162.760 170.438 179.861 1.00 120.85 ? 72  ARG K NH1 1 
ATOM 2558 N NH2 . ARG C 3 78  ? 163.800 168.472 179.332 1.00 120.85 ? 72  ARG K NH2 1 
ATOM 2559 N N   . ASP C 3 79  ? 165.117 173.771 174.860 1.00 133.00 ? 73  ASP K N   1 
ATOM 2560 C CA  . ASP C 3 79  ? 166.012 173.394 173.775 1.00 133.00 ? 73  ASP K CA  1 
ATOM 2561 C C   . ASP C 3 79  ? 167.272 172.844 174.436 1.00 133.00 ? 73  ASP K C   1 
ATOM 2562 O O   . ASP C 3 79  ? 168.100 173.606 174.944 1.00 133.00 ? 73  ASP K O   1 
ATOM 2563 C CB  . ASP C 3 79  ? 166.306 174.590 172.873 1.00 133.00 ? 73  ASP K CB  1 
ATOM 2564 C CG  . ASP C 3 79  ? 166.754 174.183 171.485 1.00 133.00 ? 73  ASP K CG  1 
ATOM 2565 O OD1 . ASP C 3 79  ? 167.444 173.150 171.354 1.00 133.00 ? 73  ASP K OD1 1 
ATOM 2566 O OD2 . ASP C 3 79  ? 166.414 174.900 170.519 1.00 133.00 ? 73  ASP K OD2 1 
ATOM 2567 N N   . ASP C 3 80  ? 167.391 171.514 174.456 1.00 134.95 ? 74  ASP K N   1 
ATOM 2568 C CA  . ASP C 3 80  ? 168.553 170.878 175.065 1.00 134.95 ? 74  ASP K CA  1 
ATOM 2569 C C   . ASP C 3 80  ? 169.835 171.202 174.310 1.00 134.95 ? 74  ASP K C   1 
ATOM 2570 O O   . ASP C 3 80  ? 170.914 171.237 174.912 1.00 134.95 ? 74  ASP K O   1 
ATOM 2571 C CB  . ASP C 3 80  ? 168.350 169.364 175.126 1.00 134.95 ? 74  ASP K CB  1 
ATOM 2572 C CG  . ASP C 3 80  ? 167.089 168.973 175.869 1.00 134.95 ? 74  ASP K CG  1 
ATOM 2573 O OD1 . ASP C 3 80  ? 166.725 169.669 176.838 1.00 134.95 ? 74  ASP K OD1 1 
ATOM 2574 O OD2 . ASP C 3 80  ? 166.460 167.967 175.483 1.00 134.95 ? 74  ASP K OD2 1 
ATOM 2575 N N   . ALA C 3 81  ? 169.740 171.435 172.999 1.00 134.08 ? 75  ALA K N   1 
ATOM 2576 C CA  . ALA C 3 81  ? 170.929 171.726 172.207 1.00 134.08 ? 75  ALA K CA  1 
ATOM 2577 C C   . ALA C 3 81  ? 171.631 172.987 172.689 1.00 134.08 ? 75  ALA K C   1 
ATOM 2578 O O   . ALA C 3 81  ? 172.859 173.091 172.590 1.00 134.08 ? 75  ALA K O   1 
ATOM 2579 C CB  . ALA C 3 81  ? 170.559 171.856 170.731 1.00 134.08 ? 75  ALA K CB  1 
ATOM 2580 N N   . LYS C 3 82  ? 170.878 173.953 173.209 1.00 134.50 ? 76  LYS K N   1 
ATOM 2581 C CA  . LYS C 3 82  ? 171.449 175.162 173.783 1.00 134.50 ? 76  LYS K CA  1 
ATOM 2582 C C   . LYS C 3 82  ? 171.278 175.219 175.294 1.00 134.50 ? 76  LYS K C   1 
ATOM 2583 O O   . LYS C 3 82  ? 171.610 176.241 175.906 1.00 134.50 ? 76  LYS K O   1 
ATOM 2584 C CB  . LYS C 3 82  ? 170.833 176.404 173.135 1.00 134.50 ? 76  LYS K CB  1 
ATOM 2585 C CG  . LYS C 3 82  ? 171.273 176.639 171.699 1.00 201.75 ? 76  LYS K CG  1 
ATOM 2586 C CD  . LYS C 3 82  ? 170.667 177.910 171.126 1.00 201.75 ? 76  LYS K CD  1 
ATOM 2587 C CE  . LYS C 3 82  ? 169.167 177.769 170.936 1.00 201.75 ? 76  LYS K CE  1 
ATOM 2588 N NZ  . LYS C 3 82  ? 168.830 176.642 170.023 1.00 201.75 ? 76  LYS K NZ  1 
ATOM 2589 N N   . ASN C 3 83  ? 170.778 174.143 175.905 1.00 133.41 ? 77  ASN K N   1 
ATOM 2590 C CA  . ASN C 3 83  ? 170.510 174.086 177.343 1.00 133.41 ? 77  ASN K CA  1 
ATOM 2591 C C   . ASN C 3 83  ? 169.688 175.290 177.793 1.00 133.41 ? 77  ASN K C   1 
ATOM 2592 O O   . ASN C 3 83  ? 170.001 175.952 178.782 1.00 133.41 ? 77  ASN K O   1 
ATOM 2593 C CB  . ASN C 3 83  ? 171.809 173.983 178.144 1.00 133.41 ? 77  ASN K CB  1 
ATOM 2594 C CG  . ASN C 3 83  ? 172.528 172.672 177.915 1.00 133.41 ? 77  ASN K CG  1 
ATOM 2595 O OD1 . ASN C 3 83  ? 171.899 171.638 177.690 1.00 133.41 ? 77  ASN K OD1 1 
ATOM 2596 N ND2 . ASN C 3 83  ? 173.854 172.707 177.967 1.00 133.41 ? 77  ASN K ND2 1 
ATOM 2597 N N   . THR C 3 84  ? 168.623 175.575 177.051 1.00 127.04 ? 78  THR K N   1 
ATOM 2598 C CA  . THR C 3 84  ? 167.838 176.781 177.255 1.00 127.04 ? 78  THR K CA  1 
ATOM 2599 C C   . THR C 3 84  ? 166.401 176.416 177.597 1.00 127.04 ? 78  THR K C   1 
ATOM 2600 O O   . THR C 3 84  ? 165.842 175.473 177.034 1.00 127.04 ? 78  THR K O   1 
ATOM 2601 C CB  . THR C 3 84  ? 167.886 177.667 176.004 1.00 127.04 ? 78  THR K CB  1 
ATOM 2602 O OG1 . THR C 3 84  ? 169.252 177.921 175.656 1.00 127.04 ? 78  THR K OG1 1 
ATOM 2603 C CG2 . THR C 3 84  ? 167.195 178.989 176.254 1.00 127.04 ? 78  THR K CG2 1 
ATOM 2604 N N   . VAL C 3 85  ? 165.814 177.151 178.537 1.00 119.97 ? 79  VAL K N   1 
ATOM 2605 C CA  . VAL C 3 85  ? 164.396 177.053 178.855 1.00 119.97 ? 79  VAL K CA  1 
ATOM 2606 C C   . VAL C 3 85  ? 163.740 178.392 178.539 1.00 119.97 ? 79  VAL K C   1 
ATOM 2607 O O   . VAL C 3 85  ? 164.254 179.452 178.915 1.00 119.97 ? 79  VAL K O   1 
ATOM 2608 C CB  . VAL C 3 85  ? 164.161 176.651 180.322 1.00 119.97 ? 79  VAL K CB  1 
ATOM 2609 C CG1 . VAL C 3 85  ? 162.682 176.389 180.571 1.00 119.97 ? 79  VAL K CG1 1 
ATOM 2610 C CG2 . VAL C 3 85  ? 164.982 175.425 180.665 1.00 119.97 ? 79  VAL K CG2 1 
ATOM 2611 N N   . TYR C 3 86  ? 162.612 178.335 177.843 1.00 116.29 ? 80  TYR K N   1 
ATOM 2612 C CA  . TYR C 3 86  ? 161.866 179.512 177.432 1.00 116.29 ? 80  TYR K CA  1 
ATOM 2613 C C   . TYR C 3 86  ? 160.504 179.527 178.106 1.00 116.29 ? 80  TYR K C   1 
ATOM 2614 O O   . TYR C 3 86  ? 159.835 178.490 178.203 1.00 116.29 ? 80  TYR K O   1 
ATOM 2615 C CB  . TYR C 3 86  ? 161.655 179.557 175.914 1.00 116.29 ? 80  TYR K CB  1 
ATOM 2616 C CG  . TYR C 3 86  ? 162.895 179.374 175.074 1.00 116.29 ? 80  TYR K CG  1 
ATOM 2617 C CD1 . TYR C 3 86  ? 163.750 180.437 174.826 1.00 116.29 ? 80  TYR K CD1 1 
ATOM 2618 C CD2 . TYR C 3 86  ? 163.195 178.143 174.506 1.00 116.29 ? 80  TYR K CD2 1 
ATOM 2619 C CE1 . TYR C 3 86  ? 164.876 180.278 174.047 1.00 116.29 ? 80  TYR K CE1 1 
ATOM 2620 C CE2 . TYR C 3 86  ? 164.320 177.973 173.728 1.00 116.29 ? 80  TYR K CE2 1 
ATOM 2621 C CZ  . TYR C 3 86  ? 165.158 179.044 173.501 1.00 116.29 ? 80  TYR K CZ  1 
ATOM 2622 O OH  . TYR C 3 86  ? 166.282 178.880 172.726 1.00 116.29 ? 80  TYR K OH  1 
ATOM 2623 N N   . LEU C 3 87  ? 160.089 180.712 178.535 1.00 107.88 ? 81  LEU K N   1 
ATOM 2624 C CA  . LEU C 3 87  ? 158.752 180.948 179.057 1.00 107.88 ? 81  LEU K CA  1 
ATOM 2625 C C   . LEU C 3 87  ? 158.086 181.989 178.173 1.00 107.88 ? 81  LEU K C   1 
ATOM 2626 O O   . LEU C 3 87  ? 158.552 183.129 178.090 1.00 107.88 ? 81  LEU K O   1 
ATOM 2627 C CB  . LEU C 3 87  ? 158.801 181.410 180.516 1.00 107.88 ? 81  LEU K CB  1 
ATOM 2628 C CG  . LEU C 3 87  ? 157.491 181.788 181.211 1.00 107.88 ? 81  LEU K CG  1 
ATOM 2629 C CD1 . LEU C 3 87  ? 156.498 180.650 181.156 1.00 107.88 ? 81  LEU K CD1 1 
ATOM 2630 C CD2 . LEU C 3 87  ? 157.749 182.200 182.650 1.00 107.88 ? 81  LEU K CD2 1 
ATOM 2631 N N   . GLN C 3 88  ? 157.014 181.591 177.508 1.00 110.52 ? 82  GLN K N   1 
ATOM 2632 C CA  . GLN C 3 88  ? 156.227 182.472 176.659 1.00 110.52 ? 82  GLN K CA  1 
ATOM 2633 C C   . GLN C 3 88  ? 155.011 182.918 177.458 1.00 110.52 ? 82  GLN K C   1 
ATOM 2634 O O   . GLN C 3 88  ? 154.153 182.098 177.798 1.00 110.52 ? 82  GLN K O   1 
ATOM 2635 C CB  . GLN C 3 88  ? 155.821 181.755 175.374 1.00 110.52 ? 82  GLN K CB  1 
ATOM 2636 C CG  . GLN C 3 88  ? 154.901 182.554 174.466 1.00 110.52 ? 82  GLN K CG  1 
ATOM 2637 C CD  . GLN C 3 88  ? 155.539 183.828 173.948 1.00 110.52 ? 82  GLN K CD  1 
ATOM 2638 O OE1 . GLN C 3 88  ? 156.763 183.957 173.904 1.00 110.52 ? 82  GLN K OE1 1 
ATOM 2639 N NE2 . GLN C 3 88  ? 154.705 184.783 173.554 1.00 110.52 ? 82  GLN K NE2 1 
ATOM 2640 N N   . MET C 3 89  ? 154.942 184.211 177.769 1.00 110.02 ? 83  MET K N   1 
ATOM 2641 C CA  . MET C 3 89  ? 153.884 184.775 178.588 1.00 110.02 ? 83  MET K CA  1 
ATOM 2642 C C   . MET C 3 89  ? 152.936 185.542 177.681 1.00 110.02 ? 83  MET K C   1 
ATOM 2643 O O   . MET C 3 89  ? 153.357 186.460 176.974 1.00 110.02 ? 83  MET K O   1 
ATOM 2644 C CB  . MET C 3 89  ? 154.468 185.691 179.662 1.00 110.02 ? 83  MET K CB  1 
ATOM 2645 C CG  . MET C 3 89  ? 155.745 185.159 180.282 1.00 110.02 ? 83  MET K CG  1 
ATOM 2646 S SD  . MET C 3 89  ? 156.289 186.114 181.707 1.00 110.02 ? 83  MET K SD  1 
ATOM 2647 C CE  . MET C 3 89  ? 156.589 187.705 180.950 1.00 110.02 ? 83  MET K CE  1 
ATOM 2648 N N   . ASN C 3 90  ? 151.669 185.153 177.689 1.00 112.18 ? 84  ASN K N   1 
ATOM 2649 C CA  . ASN C 3 90  ? 150.631 185.825 176.930 1.00 112.18 ? 84  ASN K CA  1 
ATOM 2650 C C   . ASN C 3 90  ? 149.658 186.505 177.880 1.00 112.18 ? 84  ASN K C   1 
ATOM 2651 O O   . ASN C 3 90  ? 149.622 186.209 179.076 1.00 112.18 ? 84  ASN K O   1 
ATOM 2652 C CB  . ASN C 3 90  ? 149.875 184.838 176.033 1.00 112.18 ? 84  ASN K CB  1 
ATOM 2653 C CG  . ASN C 3 90  ? 150.716 184.337 174.875 1.00 112.18 ? 84  ASN K CG  1 
ATOM 2654 O OD1 . ASN C 3 90  ? 151.926 184.562 174.819 1.00 112.18 ? 84  ASN K OD1 1 
ATOM 2655 N ND2 . ASN C 3 90  ? 150.072 183.648 173.940 1.00 112.18 ? 84  ASN K ND2 1 
ATOM 2656 N N   . SER C 3 91  ? 148.876 187.433 177.334 1.00 117.85 ? 85  SER K N   1 
ATOM 2657 C CA  . SER C 3 91  ? 147.774 188.058 178.061 1.00 117.85 ? 85  SER K CA  1 
ATOM 2658 C C   . SER C 3 91  ? 148.239 188.608 179.404 1.00 117.85 ? 85  SER K C   1 
ATOM 2659 O O   . SER C 3 91  ? 147.601 188.418 180.440 1.00 117.85 ? 85  SER K O   1 
ATOM 2660 C CB  . SER C 3 91  ? 146.620 187.074 178.243 1.00 117.85 ? 85  SER K CB  1 
ATOM 2661 O OG  . SER C 3 91  ? 146.168 186.593 176.991 1.00 117.85 ? 85  SER K OG  1 
ATOM 2662 N N   . LEU C 3 92  ? 149.381 189.287 179.380 1.00 120.99 ? 86  LEU K N   1 
ATOM 2663 C CA  . LEU C 3 92  ? 149.972 189.779 180.613 1.00 120.99 ? 86  LEU K CA  1 
ATOM 2664 C C   . LEU C 3 92  ? 149.050 190.789 181.281 1.00 120.99 ? 86  LEU K C   1 
ATOM 2665 O O   . LEU C 3 92  ? 148.329 191.540 180.624 1.00 120.99 ? 86  LEU K O   1 
ATOM 2666 C CB  . LEU C 3 92  ? 151.339 190.404 180.339 1.00 120.99 ? 86  LEU K CB  1 
ATOM 2667 C CG  . LEU C 3 92  ? 152.466 189.408 180.072 1.00 120.99 ? 86  LEU K CG  1 
ATOM 2668 C CD1 . LEU C 3 92  ? 153.789 190.120 179.892 1.00 120.99 ? 86  LEU K CD1 1 
ATOM 2669 C CD2 . LEU C 3 92  ? 152.554 188.418 181.210 1.00 120.99 ? 86  LEU K CD2 1 
ATOM 2670 N N   . LYS C 3 93  ? 149.058 190.772 182.604 1.00 126.56 ? 87  LYS K N   1 
ATOM 2671 C CA  . LYS C 3 93  ? 148.309 191.691 183.436 1.00 126.56 ? 87  LYS K CA  1 
ATOM 2672 C C   . LYS C 3 93  ? 149.275 192.414 184.359 1.00 126.56 ? 87  LYS K C   1 
ATOM 2673 O O   . LYS C 3 93  ? 150.378 191.922 184.626 1.00 126.56 ? 87  LYS K O   1 
ATOM 2674 C CB  . LYS C 3 93  ? 147.251 190.947 184.262 1.00 126.56 ? 87  LYS K CB  1 
ATOM 2675 C CG  . LYS C 3 93  ? 146.081 190.408 183.448 1.00 126.56 ? 87  LYS K CG  1 
ATOM 2676 C CD  . LYS C 3 93  ? 145.005 189.824 184.352 1.00 126.56 ? 87  LYS K CD  1 
ATOM 2677 C CE  . LYS C 3 93  ? 143.826 189.305 183.548 1.00 126.56 ? 87  LYS K CE  1 
ATOM 2678 N NZ  . LYS C 3 93  ? 142.777 188.727 184.426 1.00 126.56 ? 87  LYS K NZ  1 
ATOM 2679 N N   . PRO C 3 94  ? 148.901 193.594 184.858 1.00 134.29 ? 88  PRO K N   1 
ATOM 2680 C CA  . PRO C 3 94  ? 149.772 194.272 185.831 1.00 134.29 ? 88  PRO K CA  1 
ATOM 2681 C C   . PRO C 3 94  ? 150.075 193.420 187.052 1.00 134.29 ? 88  PRO K C   1 
ATOM 2682 O O   . PRO C 3 94  ? 151.151 193.569 187.655 1.00 134.29 ? 88  PRO K O   1 
ATOM 2683 C CB  . PRO C 3 94  ? 148.969 195.527 186.198 1.00 134.29 ? 88  PRO K CB  1 
ATOM 2684 C CG  . PRO C 3 94  ? 148.094 195.769 185.015 1.00 134.29 ? 88  PRO K CG  1 
ATOM 2685 C CD  . PRO C 3 94  ? 147.738 194.415 184.483 1.00 134.29 ? 88  PRO K CD  1 
ATOM 2686 N N   . GLU C 3 95  ? 149.169 192.510 187.420 1.00 133.44 ? 89  GLU K N   1 
ATOM 2687 C CA  . GLU C 3 95  ? 149.380 191.640 188.573 1.00 133.44 ? 89  GLU K CA  1 
ATOM 2688 C C   . GLU C 3 95  ? 150.601 190.742 188.420 1.00 133.44 ? 89  GLU K C   1 
ATOM 2689 O O   . GLU C 3 95  ? 151.101 190.224 189.425 1.00 133.44 ? 89  GLU K O   1 
ATOM 2690 C CB  . GLU C 3 95  ? 148.142 190.775 188.801 1.00 133.44 ? 89  GLU K CB  1 
ATOM 2691 C CG  . GLU C 3 95  ? 146.855 191.564 188.915 1.00 133.44 ? 89  GLU K CG  1 
ATOM 2692 C CD  . GLU C 3 95  ? 145.626 190.714 188.670 1.00 133.44 ? 89  GLU K CD  1 
ATOM 2693 O OE1 . GLU C 3 95  ? 145.779 189.525 188.314 1.00 133.44 ? 89  GLU K OE1 1 
ATOM 2694 O OE2 . GLU C 3 95  ? 144.505 191.240 188.829 1.00 133.44 ? 89  GLU K OE2 1 
ATOM 2695 N N   . ASP C 3 96  ? 151.084 190.537 187.194 1.00 126.16 ? 90  ASP K N   1 
ATOM 2696 C CA  . ASP C 3 96  ? 152.210 189.644 186.946 1.00 126.16 ? 90  ASP K CA  1 
ATOM 2697 C C   . ASP C 3 96  ? 153.560 190.324 187.118 1.00 126.16 ? 90  ASP K C   1 
ATOM 2698 O O   . ASP C 3 96  ? 154.592 189.671 186.933 1.00 126.16 ? 90  ASP K O   1 
ATOM 2699 C CB  . ASP C 3 96  ? 152.110 189.052 185.536 1.00 126.16 ? 90  ASP K CB  1 
ATOM 2700 C CG  . ASP C 3 96  ? 150.777 188.374 185.279 1.00 126.16 ? 90  ASP K CG  1 
ATOM 2701 O OD1 . ASP C 3 96  ? 150.170 187.862 186.242 1.00 126.16 ? 90  ASP K OD1 1 
ATOM 2702 O OD2 . ASP C 3 96  ? 150.336 188.352 184.110 1.00 126.16 ? 90  ASP K OD2 1 
ATOM 2703 N N   . THR C 3 97  ? 153.575 191.617 187.455 1.00 130.97 ? 91  THR K N   1 
ATOM 2704 C CA  . THR C 3 97  ? 154.842 192.324 187.626 1.00 130.97 ? 91  THR K CA  1 
ATOM 2705 C C   . THR C 3 97  ? 155.643 191.700 188.757 1.00 130.97 ? 91  THR K C   1 
ATOM 2706 O O   . THR C 3 97  ? 155.176 191.656 189.900 1.00 130.97 ? 91  THR K O   1 
ATOM 2707 C CB  . THR C 3 97  ? 154.574 193.798 187.922 1.00 130.97 ? 91  THR K CB  1 
ATOM 2708 O OG1 . THR C 3 97  ? 153.824 194.375 186.847 1.00 130.97 ? 91  THR K OG1 1 
ATOM 2709 C CG2 . THR C 3 97  ? 155.883 194.550 188.098 1.00 130.97 ? 91  THR K CG2 1 
ATOM 2710 N N   . ALA C 3 98  ? 156.851 191.235 188.447 1.00 120.11 ? 92  ALA K N   1 
ATOM 2711 C CA  . ALA C 3 98  ? 157.632 190.479 189.419 1.00 120.11 ? 92  ALA K CA  1 
ATOM 2712 C C   . ALA C 3 98  ? 158.997 190.152 188.830 1.00 120.11 ? 92  ALA K C   1 
ATOM 2713 O O   . ALA C 3 98  ? 159.242 190.337 187.635 1.00 120.11 ? 92  ALA K O   1 
ATOM 2714 C CB  . ALA C 3 98  ? 156.923 189.189 189.823 1.00 120.11 ? 92  ALA K CB  1 
ATOM 2715 N N   . VAL C 3 99  ? 159.879 189.650 189.685 1.00 112.81 ? 93  VAL K N   1 
ATOM 2716 C CA  . VAL C 3 99  ? 161.161 189.116 189.241 1.00 112.81 ? 93  VAL K CA  1 
ATOM 2717 C C   . VAL C 3 99  ? 160.996 187.622 188.996 1.00 112.81 ? 93  VAL K C   1 
ATOM 2718 O O   . VAL C 3 99  ? 160.468 186.897 189.851 1.00 112.81 ? 93  VAL K O   1 
ATOM 2719 C CB  . VAL C 3 99  ? 162.265 189.392 190.274 1.00 112.81 ? 93  VAL K CB  1 
ATOM 2720 C CG1 . VAL C 3 99  ? 163.605 188.913 189.754 1.00 112.81 ? 93  VAL K CG1 1 
ATOM 2721 C CG2 . VAL C 3 99  ? 162.321 190.870 190.605 1.00 112.81 ? 93  VAL K CG2 1 
ATOM 2722 N N   . TYR C 3 100 ? 161.425 187.161 187.823 1.00 107.29 ? 94  TYR K N   1 
ATOM 2723 C CA  . TYR C 3 100 ? 161.270 185.770 187.422 1.00 107.29 ? 94  TYR K CA  1 
ATOM 2724 C C   . TYR C 3 100 ? 162.605 185.037 187.495 1.00 107.29 ? 94  TYR K C   1 
ATOM 2725 O O   . TYR C 3 100 ? 163.648 185.583 187.126 1.00 107.29 ? 94  TYR K O   1 
ATOM 2726 C CB  . TYR C 3 100 ? 160.683 185.675 186.017 1.00 107.29 ? 94  TYR K CB  1 
ATOM 2727 C CG  . TYR C 3 100 ? 159.202 185.981 185.953 1.00 107.29 ? 94  TYR K CG  1 
ATOM 2728 C CD1 . TYR C 3 100 ? 158.723 187.257 186.215 1.00 107.29 ? 94  TYR K CD1 1 
ATOM 2729 C CD2 . TYR C 3 100 ? 158.285 184.997 185.621 1.00 107.29 ? 94  TYR K CD2 1 
ATOM 2730 C CE1 . TYR C 3 100 ? 157.378 187.537 186.154 1.00 107.29 ? 94  TYR K CE1 1 
ATOM 2731 C CE2 . TYR C 3 100 ? 156.939 185.271 185.555 1.00 107.29 ? 94  TYR K CE2 1 
ATOM 2732 C CZ  . TYR C 3 100 ? 156.493 186.541 185.821 1.00 107.29 ? 94  TYR K CZ  1 
ATOM 2733 O OH  . TYR C 3 100 ? 155.150 186.816 185.756 1.00 107.29 ? 94  TYR K OH  1 
ATOM 2734 N N   . TYR C 3 101 ? 162.560 183.792 187.973 1.00 109.52 ? 95  TYR K N   1 
ATOM 2735 C CA  . TYR C 3 101 ? 163.743 182.989 188.256 1.00 109.52 ? 95  TYR K CA  1 
ATOM 2736 C C   . TYR C 3 101 ? 163.615 181.615 187.615 1.00 109.52 ? 95  TYR K C   1 
ATOM 2737 O O   . TYR C 3 101 ? 162.543 181.008 187.646 1.00 109.52 ? 95  TYR K O   1 
ATOM 2738 C CB  . TYR C 3 101 ? 163.938 182.799 189.763 1.00 109.52 ? 95  TYR K CB  1 
ATOM 2739 C CG  . TYR C 3 101 ? 164.082 184.068 190.563 1.00 109.52 ? 95  TYR K CG  1 
ATOM 2740 C CD1 . TYR C 3 101 ? 162.974 184.707 191.097 1.00 109.52 ? 95  TYR K CD1 1 
ATOM 2741 C CD2 . TYR C 3 101 ? 165.333 184.612 190.807 1.00 109.52 ? 95  TYR K CD2 1 
ATOM 2742 C CE1 . TYR C 3 101 ? 163.110 185.863 191.840 1.00 109.52 ? 95  TYR K CE1 1 
ATOM 2743 C CE2 . TYR C 3 101 ? 165.479 185.765 191.545 1.00 109.52 ? 95  TYR K CE2 1 
ATOM 2744 C CZ  . TYR C 3 101 ? 164.366 186.387 192.059 1.00 109.52 ? 95  TYR K CZ  1 
ATOM 2745 O OH  . TYR C 3 101 ? 164.515 187.540 192.795 1.00 109.52 ? 95  TYR K OH  1 
ATOM 2746 N N   . CYS C 3 102 ? 164.709 181.115 187.051 1.00 109.83 ? 96  CYS K N   1 
ATOM 2747 C CA  . CYS C 3 102 ? 164.786 179.711 186.677 1.00 109.83 ? 96  CYS K CA  1 
ATOM 2748 C C   . CYS C 3 102 ? 165.574 178.937 187.727 1.00 109.83 ? 96  CYS K C   1 
ATOM 2749 O O   . CYS C 3 102 ? 166.459 179.478 188.394 1.00 109.83 ? 96  CYS K O   1 
ATOM 2750 C CB  . CYS C 3 102 ? 165.429 179.525 185.301 1.00 109.83 ? 96  CYS K CB  1 
ATOM 2751 S SG  . CYS C 3 102 ? 164.462 180.177 183.921 1.00 109.83 ? 96  CYS K SG  1 
ATOM 2752 N N   . ALA C 3 103 ? 165.235 177.658 187.867 1.00 105.11 ? 97  ALA K N   1 
ATOM 2753 C CA  . ALA C 3 103 ? 165.863 176.805 188.865 1.00 105.11 ? 97  ALA K CA  1 
ATOM 2754 C C   . ALA C 3 103 ? 165.927 175.379 188.344 1.00 105.11 ? 97  ALA K C   1 
ATOM 2755 O O   . ALA C 3 103 ? 165.024 174.917 187.646 1.00 105.11 ? 97  ALA K O   1 
ATOM 2756 C CB  . ALA C 3 103 ? 165.111 176.844 190.195 1.00 105.11 ? 97  ALA K CB  1 
ATOM 2757 N N   . ILE C 3 104 ? 166.995 174.679 188.716 1.00 111.97 ? 98  ILE K N   1 
ATOM 2758 C CA  . ILE C 3 104 ? 167.292 173.344 188.209 1.00 111.97 ? 98  ILE K CA  1 
ATOM 2759 C C   . ILE C 3 104 ? 166.930 172.327 189.280 1.00 111.97 ? 98  ILE K C   1 
ATOM 2760 O O   . ILE C 3 104 ? 167.428 172.400 190.409 1.00 111.97 ? 98  ILE K O   1 
ATOM 2761 C CB  . ILE C 3 104 ? 168.769 173.219 187.812 1.00 111.97 ? 98  ILE K CB  1 
ATOM 2762 C CG1 . ILE C 3 104 ? 169.091 174.177 186.664 1.00 111.97 ? 98  ILE K CG1 1 
ATOM 2763 C CG2 . ILE C 3 104 ? 169.103 171.784 187.445 1.00 111.97 ? 98  ILE K CG2 1 
ATOM 2764 C CD1 . ILE C 3 104 ? 170.543 174.189 186.270 1.00 111.97 ? 98  ILE K CD1 1 
ATOM 2765 N N   . ASP C 3 105 ? 166.070 171.373 188.931 1.00 112.34 ? 99  ASP K N   1 
ATOM 2766 C CA  . ASP C 3 105 ? 165.701 170.296 189.838 1.00 112.34 ? 99  ASP K CA  1 
ATOM 2767 C C   . ASP C 3 105 ? 166.749 169.198 189.721 1.00 112.34 ? 99  ASP K C   1 
ATOM 2768 O O   . ASP C 3 105 ? 166.845 168.529 188.686 1.00 112.34 ? 99  ASP K O   1 
ATOM 2769 C CB  . ASP C 3 105 ? 164.309 169.776 189.493 1.00 112.34 ? 99  ASP K CB  1 
ATOM 2770 C CG  . ASP C 3 105 ? 163.776 168.815 190.522 1.00 112.34 ? 99  ASP K CG  1 
ATOM 2771 O OD1 . ASP C 3 105 ? 164.500 168.509 191.490 1.00 112.34 ? 99  ASP K OD1 1 
ATOM 2772 O OD2 . ASP C 3 105 ? 162.626 168.367 190.362 1.00 112.34 ? 99  ASP K OD2 1 
ATOM 2773 N N   . SER C 3 106 ? 167.537 169.007 190.779 1.00 114.46 ? 100 SER K N   1 
ATOM 2774 C CA  . SER C 3 106 ? 168.629 168.045 190.732 1.00 114.46 ? 100 SER K CA  1 
ATOM 2775 C C   . SER C 3 106 ? 168.169 166.599 190.871 1.00 114.46 ? 100 SER K C   1 
ATOM 2776 O O   . SER C 3 106 ? 168.992 165.694 190.704 1.00 114.46 ? 100 SER K O   1 
ATOM 2777 C CB  . SER C 3 106 ? 169.661 168.356 191.820 1.00 114.46 ? 100 SER K CB  1 
ATOM 2778 O OG  . SER C 3 106 ? 170.415 169.512 191.499 1.00 114.46 ? 100 SER K OG  1 
ATOM 2779 N N   . ASP C 3 107 ? 166.898 166.352 191.173 1.00 108.64 ? 101 ASP K N   1 
ATOM 2780 C CA  . ASP C 3 107 ? 166.377 164.997 191.282 1.00 108.64 ? 101 ASP K CA  1 
ATOM 2781 C C   . ASP C 3 107 ? 165.733 164.599 189.959 1.00 108.64 ? 101 ASP K C   1 
ATOM 2782 O O   . ASP C 3 107 ? 164.772 165.235 189.518 1.00 108.64 ? 101 ASP K O   1 
ATOM 2783 C CB  . ASP C 3 107 ? 165.365 164.879 192.422 1.00 108.64 ? 101 ASP K CB  1 
ATOM 2784 C CG  . ASP C 3 107 ? 164.859 163.460 192.601 1.00 108.64 ? 101 ASP K CG  1 
ATOM 2785 O OD1 . ASP C 3 107 ? 165.619 162.514 192.306 1.00 108.64 ? 101 ASP K OD1 1 
ATOM 2786 O OD2 . ASP C 3 107 ? 163.696 163.284 193.014 1.00 108.64 ? 101 ASP K OD2 1 
ATOM 2787 N N   . THR C 3 108 ? 166.252 163.537 189.340 1.00 112.17 ? 102 THR K N   1 
ATOM 2788 C CA  . THR C 3 108 ? 165.659 163.020 188.113 1.00 112.17 ? 102 THR K CA  1 
ATOM 2789 C C   . THR C 3 108 ? 164.283 162.411 188.342 1.00 112.17 ? 102 THR K C   1 
ATOM 2790 O O   . THR C 3 108 ? 163.584 162.115 187.367 1.00 112.17 ? 102 THR K O   1 
ATOM 2791 C CB  . THR C 3 108 ? 166.578 161.980 187.478 1.00 112.17 ? 102 THR K CB  1 
ATOM 2792 O OG1 . THR C 3 108 ? 166.747 160.880 188.380 1.00 112.17 ? 102 THR K OG1 1 
ATOM 2793 C CG2 . THR C 3 108 ? 167.933 162.590 187.172 1.00 112.17 ? 102 THR K CG2 1 
ATOM 2794 N N   . PHE C 3 109 ? 163.886 162.212 189.596 1.00 108.35 ? 103 PHE K N   1 
ATOM 2795 C CA  . PHE C 3 109 ? 162.570 161.698 189.936 1.00 108.35 ? 103 PHE K CA  1 
ATOM 2796 C C   . PHE C 3 109 ? 161.587 162.804 190.295 1.00 108.35 ? 103 PHE K C   1 
ATOM 2797 O O   . PHE C 3 109 ? 160.488 162.510 190.779 1.00 108.35 ? 103 PHE K O   1 
ATOM 2798 C CB  . PHE C 3 109 ? 162.681 160.686 191.077 1.00 108.35 ? 103 PHE K CB  1 
ATOM 2799 C CG  . PHE C 3 109 ? 163.507 159.478 190.734 1.00 108.35 ? 103 PHE K CG  1 
ATOM 2800 C CD1 . PHE C 3 109 ? 162.951 158.422 190.032 1.00 108.35 ? 103 PHE K CD1 1 
ATOM 2801 C CD2 . PHE C 3 109 ? 164.837 159.402 191.105 1.00 108.35 ? 103 PHE K CD2 1 
ATOM 2802 C CE1 . PHE C 3 109 ? 163.706 157.314 189.710 1.00 108.35 ? 103 PHE K CE1 1 
ATOM 2803 C CE2 . PHE C 3 109 ? 165.597 158.294 190.785 1.00 108.35 ? 103 PHE K CE2 1 
ATOM 2804 C CZ  . PHE C 3 109 ? 165.030 157.250 190.087 1.00 108.35 ? 103 PHE K CZ  1 
ATOM 2805 N N   . TYR C 3 110 ? 161.965 164.067 190.084 1.00 100.21 ? 104 TYR K N   1 
ATOM 2806 C CA  . TYR C 3 110 ? 161.038 165.199 190.140 1.00 100.21 ? 104 TYR K CA  1 
ATOM 2807 C C   . TYR C 3 110 ? 160.510 165.441 191.555 1.00 100.21 ? 104 TYR K C   1 
ATOM 2808 O O   . TYR C 3 110 ? 159.350 165.809 191.745 1.00 100.21 ? 104 TYR K O   1 
ATOM 2809 C CB  . TYR C 3 110 ? 159.879 165.009 189.159 1.00 100.21 ? 104 TYR K CB  1 
ATOM 2810 C CG  . TYR C 3 110 ? 160.310 164.663 187.753 1.00 100.21 ? 104 TYR K CG  1 
ATOM 2811 C CD1 . TYR C 3 110 ? 161.489 165.167 187.224 1.00 100.21 ? 104 TYR K CD1 1 
ATOM 2812 C CD2 . TYR C 3 110 ? 159.539 163.827 186.956 1.00 100.21 ? 104 TYR K CD2 1 
ATOM 2813 C CE1 . TYR C 3 110 ? 161.887 164.852 185.944 1.00 100.21 ? 104 TYR K CE1 1 
ATOM 2814 C CE2 . TYR C 3 110 ? 159.929 163.507 185.671 1.00 100.21 ? 104 TYR K CE2 1 
ATOM 2815 C CZ  . TYR C 3 110 ? 161.105 164.023 185.171 1.00 100.21 ? 104 TYR K CZ  1 
ATOM 2816 O OH  . TYR C 3 110 ? 161.510 163.714 183.894 1.00 100.21 ? 104 TYR K OH  1 
ATOM 2817 N N   . SER C 3 111 ? 161.366 165.247 192.555 1.00 93.64  ? 105 SER K N   1 
ATOM 2818 C CA  . SER C 3 111 ? 160.984 165.589 193.917 1.00 93.64  ? 105 SER K CA  1 
ATOM 2819 C C   . SER C 3 111 ? 161.124 167.077 194.209 1.00 93.64  ? 105 SER K C   1 
ATOM 2820 O O   . SER C 3 111 ? 160.680 167.523 195.270 1.00 93.64  ? 105 SER K O   1 
ATOM 2821 C CB  . SER C 3 111 ? 161.816 164.800 194.926 1.00 93.64  ? 105 SER K CB  1 
ATOM 2822 O OG  . SER C 3 111 ? 163.106 165.368 195.064 1.00 93.64  ? 105 SER K OG  1 
ATOM 2823 N N   . GLY C 3 112 ? 161.738 167.841 193.311 1.00 99.33  ? 106 GLY K N   1 
ATOM 2824 C CA  . GLY C 3 112 ? 161.809 169.285 193.454 1.00 99.33  ? 106 GLY K CA  1 
ATOM 2825 C C   . GLY C 3 112 ? 162.944 169.806 194.304 1.00 99.33  ? 106 GLY K C   1 
ATOM 2826 O O   . GLY C 3 112 ? 162.769 170.800 195.020 1.00 99.33  ? 106 GLY K O   1 
ATOM 2827 N N   . SER C 3 113 ? 164.112 169.178 194.240 1.00 108.33 ? 107 SER K N   1 
ATOM 2828 C CA  . SER C 3 113 ? 165.271 169.628 195.009 1.00 108.33 ? 107 SER K CA  1 
ATOM 2829 C C   . SER C 3 113 ? 166.014 170.669 194.186 1.00 108.33 ? 107 SER K C   1 
ATOM 2830 O O   . SER C 3 113 ? 166.858 170.345 193.352 1.00 108.33 ? 107 SER K O   1 
ATOM 2831 C CB  . SER C 3 113 ? 166.174 168.455 195.366 1.00 108.33 ? 107 SER K CB  1 
ATOM 2832 O OG  . SER C 3 113 ? 167.423 168.916 195.849 1.00 108.33 ? 107 SER K OG  1 
ATOM 2833 N N   . TYR C 3 114 ? 165.707 171.942 194.439 1.00 106.21 ? 108 TYR K N   1 
ATOM 2834 C CA  . TYR C 3 114 ? 166.249 173.051 193.659 1.00 106.21 ? 108 TYR K CA  1 
ATOM 2835 C C   . TYR C 3 114 ? 167.528 173.552 194.316 1.00 106.21 ? 108 TYR K C   1 
ATOM 2836 O O   . TYR C 3 114 ? 167.484 174.228 195.348 1.00 106.21 ? 108 TYR K O   1 
ATOM 2837 C CB  . TYR C 3 114 ? 165.222 174.169 193.538 1.00 106.21 ? 108 TYR K CB  1 
ATOM 2838 C CG  . TYR C 3 114 ? 163.962 173.735 192.846 1.00 106.21 ? 108 TYR K CG  1 
ATOM 2839 C CD1 . TYR C 3 114 ? 163.969 173.412 191.504 1.00 106.21 ? 108 TYR K CD1 1 
ATOM 2840 C CD2 . TYR C 3 114 ? 162.766 173.653 193.531 1.00 106.21 ? 108 TYR K CD2 1 
ATOM 2841 C CE1 . TYR C 3 114 ? 162.824 173.015 190.866 1.00 106.21 ? 108 TYR K CE1 1 
ATOM 2842 C CE2 . TYR C 3 114 ? 161.612 173.262 192.900 1.00 106.21 ? 108 TYR K CE2 1 
ATOM 2843 C CZ  . TYR C 3 114 ? 161.648 172.941 191.566 1.00 106.21 ? 108 TYR K CZ  1 
ATOM 2844 O OH  . TYR C 3 114 ? 160.506 172.546 190.917 1.00 106.21 ? 108 TYR K OH  1 
ATOM 2845 N N   . ASP C 3 115 ? 168.666 173.225 193.712 1.00 118.02 ? 109 ASP K N   1 
ATOM 2846 C CA  . ASP C 3 115 ? 169.964 173.625 194.230 1.00 118.02 ? 109 ASP K CA  1 
ATOM 2847 C C   . ASP C 3 115 ? 170.522 174.874 193.566 1.00 118.02 ? 109 ASP K C   1 
ATOM 2848 O O   . ASP C 3 115 ? 171.298 175.599 194.196 1.00 118.02 ? 109 ASP K O   1 
ATOM 2849 C CB  . ASP C 3 115 ? 170.968 172.479 194.068 1.00 118.02 ? 109 ASP K CB  1 
ATOM 2850 C CG  . ASP C 3 115 ? 170.499 171.200 194.728 1.00 118.02 ? 109 ASP K CG  1 
ATOM 2851 O OD1 . ASP C 3 115 ? 169.651 171.278 195.642 1.00 118.02 ? 109 ASP K OD1 1 
ATOM 2852 O OD2 . ASP C 3 115 ? 170.981 170.119 194.332 1.00 118.02 ? 109 ASP K OD2 1 
ATOM 2853 N N   . TYR C 3 116 ? 170.148 175.151 192.318 1.00 121.58 ? 110 TYR K N   1 
ATOM 2854 C CA  . TYR C 3 116 ? 170.680 176.280 191.567 1.00 121.58 ? 110 TYR K CA  1 
ATOM 2855 C C   . TYR C 3 116 ? 169.549 177.215 191.163 1.00 121.58 ? 110 TYR K C   1 
ATOM 2856 O O   . TYR C 3 116 ? 168.541 176.770 190.605 1.00 121.58 ? 110 TYR K O   1 
ATOM 2857 C CB  . TYR C 3 116 ? 171.442 175.800 190.331 1.00 121.58 ? 110 TYR K CB  1 
ATOM 2858 C CG  . TYR C 3 116 ? 172.612 174.903 190.656 1.00 121.58 ? 110 TYR K CG  1 
ATOM 2859 C CD1 . TYR C 3 116 ? 173.814 175.434 191.102 1.00 121.58 ? 110 TYR K CD1 1 
ATOM 2860 C CD2 . TYR C 3 116 ? 172.517 173.524 190.517 1.00 121.58 ? 110 TYR K CD2 1 
ATOM 2861 C CE1 . TYR C 3 116 ? 174.889 174.620 191.401 1.00 121.58 ? 110 TYR K CE1 1 
ATOM 2862 C CE2 . TYR C 3 116 ? 173.591 172.698 190.814 1.00 121.58 ? 110 TYR K CE2 1 
ATOM 2863 C CZ  . TYR C 3 116 ? 174.773 173.254 191.256 1.00 121.58 ? 110 TYR K CZ  1 
ATOM 2864 O OH  . TYR C 3 116 ? 175.848 172.446 191.555 1.00 121.58 ? 110 TYR K OH  1 
ATOM 2865 N N   . TRP C 3 117 ? 169.722 178.508 191.445 1.00 116.76 ? 111 TRP K N   1 
ATOM 2866 C CA  . TRP C 3 117 ? 168.768 179.544 191.067 1.00 116.76 ? 111 TRP K CA  1 
ATOM 2867 C C   . TRP C 3 117 ? 169.347 180.610 190.150 1.00 116.76 ? 111 TRP K C   1 
ATOM 2868 O O   . TRP C 3 117 ? 168.629 181.107 189.279 1.00 116.76 ? 111 TRP K O   1 
ATOM 2869 C CB  . TRP C 3 117 ? 168.197 180.230 192.318 1.00 116.76 ? 111 TRP K CB  1 
ATOM 2870 C CG  . TRP C 3 117 ? 167.285 179.354 193.105 1.00 116.76 ? 111 TRP K CG  1 
ATOM 2871 C CD1 . TRP C 3 117 ? 167.627 178.522 194.127 1.00 116.76 ? 111 TRP K CD1 1 
ATOM 2872 C CD2 . TRP C 3 117 ? 165.872 179.216 192.930 1.00 116.76 ? 111 TRP K CD2 1 
ATOM 2873 N NE1 . TRP C 3 117 ? 166.514 177.874 194.601 1.00 116.76 ? 111 TRP K NE1 1 
ATOM 2874 C CE2 . TRP C 3 117 ? 165.423 178.284 193.881 1.00 116.76 ? 111 TRP K CE2 1 
ATOM 2875 C CE3 . TRP C 3 117 ? 164.944 179.792 192.061 1.00 116.76 ? 111 TRP K CE3 1 
ATOM 2876 C CZ2 . TRP C 3 117 ? 164.087 177.914 193.987 1.00 116.76 ? 111 TRP K CZ2 1 
ATOM 2877 C CZ3 . TRP C 3 117 ? 163.622 179.424 192.168 1.00 116.76 ? 111 TRP K CZ3 1 
ATOM 2878 C CH2 . TRP C 3 117 ? 163.204 178.494 193.123 1.00 116.76 ? 111 TRP K CH2 1 
ATOM 2879 N N   . GLY C 3 118 ? 170.617 180.962 190.310 1.00 124.54 ? 112 GLY K N   1 
ATOM 2880 C CA  . GLY C 3 118 ? 171.187 182.030 189.504 1.00 124.54 ? 112 GLY K CA  1 
ATOM 2881 C C   . GLY C 3 118 ? 170.553 183.366 189.838 1.00 124.54 ? 112 GLY K C   1 
ATOM 2882 O O   . GLY C 3 118 ? 170.416 183.741 191.008 1.00 124.54 ? 112 GLY K O   1 
ATOM 2883 N N   . GLN C 3 119 ? 170.155 184.100 188.801 1.00 127.31 ? 113 GLN K N   1 
ATOM 2884 C CA  . GLN C 3 119 ? 169.627 185.448 188.951 1.00 127.31 ? 113 GLN K CA  1 
ATOM 2885 C C   . GLN C 3 119 ? 168.370 185.583 188.108 1.00 127.31 ? 113 GLN K C   1 
ATOM 2886 O O   . GLN C 3 119 ? 168.348 185.148 186.954 1.00 127.31 ? 113 GLN K O   1 
ATOM 2887 C CB  . GLN C 3 119 ? 170.663 186.498 188.533 1.00 127.31 ? 113 GLN K CB  1 
ATOM 2888 C CG  . GLN C 3 119 ? 170.130 187.916 188.533 1.00 127.31 ? 113 GLN K CG  1 
ATOM 2889 C CD  . GLN C 3 119 ? 169.685 188.368 189.910 1.00 127.31 ? 113 GLN K CD  1 
ATOM 2890 O OE1 . GLN C 3 119 ? 170.340 188.081 190.912 1.00 127.31 ? 113 GLN K OE1 1 
ATOM 2891 N NE2 . GLN C 3 119 ? 168.563 189.077 189.966 1.00 127.31 ? 113 GLN K NE2 1 
ATOM 2892 N N   . GLY C 3 120 ? 167.326 186.171 188.687 1.00 125.25 ? 114 GLY K N   1 
ATOM 2893 C CA  . GLY C 3 120 ? 166.106 186.424 187.957 1.00 125.25 ? 114 GLY K CA  1 
ATOM 2894 C C   . GLY C 3 120 ? 166.205 187.657 187.076 1.00 125.25 ? 114 GLY K C   1 
ATOM 2895 O O   . GLY C 3 120 ? 167.242 188.314 186.971 1.00 125.25 ? 114 GLY K O   1 
ATOM 2896 N N   . THR C 3 121 ? 165.083 187.967 186.428 1.00 123.83 ? 115 THR K N   1 
ATOM 2897 C CA  . THR C 3 121 ? 164.956 189.109 185.537 1.00 123.83 ? 115 THR K CA  1 
ATOM 2898 C C   . THR C 3 121 ? 163.638 189.814 185.820 1.00 123.83 ? 115 THR K C   1 
ATOM 2899 O O   . THR C 3 121 ? 162.626 189.165 186.095 1.00 123.83 ? 115 THR K O   1 
ATOM 2900 C CB  . THR C 3 121 ? 165.026 188.678 184.065 1.00 123.83 ? 115 THR K CB  1 
ATOM 2901 O OG1 . THR C 3 121 ? 164.793 189.810 183.218 1.00 123.83 ? 115 THR K OG1 1 
ATOM 2902 C CG2 . THR C 3 121 ? 163.994 187.593 183.766 1.00 123.83 ? 115 THR K CG2 1 
ATOM 2903 N N   . GLN C 3 122 ? 163.657 191.144 185.765 1.00 126.65 ? 116 GLN K N   1 
ATOM 2904 C CA  . GLN C 3 122 ? 162.490 191.941 186.116 1.00 126.65 ? 116 GLN K CA  1 
ATOM 2905 C C   . GLN C 3 122 ? 161.488 191.958 184.970 1.00 126.65 ? 116 GLN K C   1 
ATOM 2906 O O   . GLN C 3 122 ? 161.864 192.157 183.813 1.00 126.65 ? 116 GLN K O   1 
ATOM 2907 C CB  . GLN C 3 122 ? 162.916 193.366 186.467 1.00 126.65 ? 116 GLN K CB  1 
ATOM 2908 C CG  . GLN C 3 122 ? 161.767 194.327 186.695 1.00 126.65 ? 116 GLN K CG  1 
ATOM 2909 C CD  . GLN C 3 122 ? 160.898 193.937 187.869 1.00 126.65 ? 116 GLN K CD  1 
ATOM 2910 O OE1 . GLN C 3 122 ? 161.374 193.823 188.998 1.00 126.65 ? 116 GLN K OE1 1 
ATOM 2911 N NE2 . GLN C 3 122 ? 159.612 193.734 187.610 1.00 126.65 ? 116 GLN K NE2 1 
ATOM 2912 N N   . VAL C 3 123 ? 160.212 191.751 185.289 1.00 123.57 ? 117 VAL K N   1 
ATOM 2913 C CA  . VAL C 3 123 ? 159.129 191.852 184.322 1.00 123.57 ? 117 VAL K CA  1 
ATOM 2914 C C   . VAL C 3 123 ? 158.096 192.818 184.880 1.00 123.57 ? 117 VAL K C   1 
ATOM 2915 O O   . VAL C 3 123 ? 157.555 192.596 185.970 1.00 123.57 ? 117 VAL K O   1 
ATOM 2916 C CB  . VAL C 3 123 ? 158.493 190.487 184.025 1.00 123.57 ? 117 VAL K CB  1 
ATOM 2917 C CG1 . VAL C 3 123 ? 157.260 190.651 183.155 1.00 123.57 ? 117 VAL K CG1 1 
ATOM 2918 C CG2 . VAL C 3 123 ? 159.513 189.575 183.364 1.00 123.57 ? 117 VAL K CG2 1 
ATOM 2919 N N   . THR C 3 124 ? 157.826 193.886 184.137 1.00 134.44 ? 118 THR K N   1 
ATOM 2920 C CA  . THR C 3 124 ? 156.893 194.923 184.545 1.00 134.44 ? 118 THR K CA  1 
ATOM 2921 C C   . THR C 3 124 ? 155.790 195.011 183.506 1.00 134.44 ? 118 THR K C   1 
ATOM 2922 O O   . THR C 3 124 ? 156.063 195.003 182.299 1.00 134.44 ? 118 THR K O   1 
ATOM 2923 C CB  . THR C 3 124 ? 157.591 196.276 184.692 1.00 134.44 ? 118 THR K CB  1 
ATOM 2924 O OG1 . THR C 3 124 ? 158.776 196.126 185.481 1.00 134.44 ? 118 THR K OG1 1 
ATOM 2925 C CG2 . THR C 3 124 ? 156.672 197.276 185.370 1.00 134.44 ? 118 THR K CG2 1 
ATOM 2926 N N   . VAL C 3 125 ? 154.549 195.074 183.972 1.00 138.41 ? 119 VAL K N   1 
ATOM 2927 C CA  . VAL C 3 125 ? 153.391 195.284 183.114 1.00 138.41 ? 119 VAL K CA  1 
ATOM 2928 C C   . VAL C 3 125 ? 152.704 196.561 183.578 1.00 138.41 ? 119 VAL K C   1 
ATOM 2929 O O   . VAL C 3 125 ? 152.286 196.659 184.739 1.00 138.41 ? 119 VAL K O   1 
ATOM 2930 C CB  . VAL C 3 125 ? 152.428 194.088 183.150 1.00 138.41 ? 119 VAL K CB  1 
ATOM 2931 C CG1 . VAL C 3 125 ? 151.299 194.289 182.156 1.00 138.41 ? 119 VAL K CG1 1 
ATOM 2932 C CG2 . VAL C 3 125 ? 153.179 192.800 182.853 1.00 138.41 ? 119 VAL K CG2 1 
ATOM 2933 N N   . SER C 3 126 ? 152.590 197.534 182.679 1.00 138.86 ? 120 SER K N   1 
ATOM 2934 C CA  . SER C 3 126 ? 152.082 198.854 183.039 1.00 138.86 ? 120 SER K CA  1 
ATOM 2935 C C   . SER C 3 126 ? 150.609 198.789 183.401 1.00 138.86 ? 120 SER K C   1 
ATOM 2936 O O   . SER C 3 126 ? 149.749 198.827 182.523 1.00 138.86 ? 120 SER K O   1 
ATOM 2937 C CB  . SER C 3 126 ? 152.293 199.847 181.896 1.00 138.86 ? 120 SER K CB  1 
ATOM 2938 O OG  . SER C 3 126 ? 151.843 201.143 182.251 1.00 138.86 ? 120 SER K OG  1 
ATOM 2939 N N   . ASP D 4 1   ? 163.213 134.157 178.113 1.00 85.68  ? 2   ASP L N   1 
ATOM 2940 C CA  . ASP D 4 1   ? 164.265 134.463 177.152 1.00 85.68  ? 2   ASP L CA  1 
ATOM 2941 C C   . ASP D 4 1   ? 164.096 135.863 176.577 1.00 85.68  ? 2   ASP L C   1 
ATOM 2942 O O   . ASP D 4 1   ? 165.072 136.557 176.302 1.00 85.68  ? 2   ASP L O   1 
ATOM 2943 C CB  . ASP D 4 1   ? 164.272 133.439 176.014 1.00 85.68  ? 2   ASP L CB  1 
ATOM 2944 C CG  . ASP D 4 1   ? 164.355 132.015 176.512 1.00 85.68  ? 2   ASP L CG  1 
ATOM 2945 O OD1 . ASP D 4 1   ? 164.919 131.801 177.606 1.00 85.68  ? 2   ASP L OD1 1 
ATOM 2946 O OD2 . ASP D 4 1   ? 163.855 131.111 175.808 1.00 85.68  ? 2   ASP L OD2 1 
ATOM 2947 N N   . ILE D 4 2   ? 162.845 136.270 176.393 1.00 76.81  ? 3   ILE L N   1 
ATOM 2948 C CA  . ILE D 4 2   ? 162.510 137.527 175.737 1.00 76.81  ? 3   ILE L CA  1 
ATOM 2949 C C   . ILE D 4 2   ? 161.995 138.492 176.794 1.00 76.81  ? 3   ILE L C   1 
ATOM 2950 O O   . ILE D 4 2   ? 160.980 138.223 177.447 1.00 76.81  ? 3   ILE L O   1 
ATOM 2951 C CB  . ILE D 4 2   ? 161.472 137.322 174.626 1.00 76.81  ? 3   ILE L CB  1 
ATOM 2952 C CG1 . ILE D 4 2   ? 161.935 136.230 173.661 1.00 76.81  ? 3   ILE L CG1 1 
ATOM 2953 C CG2 . ILE D 4 2   ? 161.231 138.627 173.893 1.00 76.81  ? 3   ILE L CG2 1 
ATOM 2954 C CD1 . ILE D 4 2   ? 160.882 135.820 172.664 1.00 76.81  ? 3   ILE L CD1 1 
ATOM 2955 N N   . GLN D 4 3   ? 162.686 139.617 176.953 1.00 84.55  ? 4   GLN L N   1 
ATOM 2956 C CA  . GLN D 4 3   ? 162.335 140.625 177.942 1.00 84.55  ? 4   GLN L CA  1 
ATOM 2957 C C   . GLN D 4 3   ? 161.645 141.805 177.275 1.00 84.55  ? 4   GLN L C   1 
ATOM 2958 O O   . GLN D 4 3   ? 162.075 142.276 176.220 1.00 84.55  ? 4   GLN L O   1 
ATOM 2959 C CB  . GLN D 4 3   ? 163.577 141.113 178.689 1.00 84.55  ? 4   GLN L CB  1 
ATOM 2960 C CG  . GLN D 4 3   ? 163.263 142.035 179.853 1.00 84.55  ? 4   GLN L CG  1 
ATOM 2961 C CD  . GLN D 4 3   ? 162.394 141.363 180.900 1.00 84.55  ? 4   GLN L CD  1 
ATOM 2962 O OE1 . GLN D 4 3   ? 162.670 140.240 181.320 1.00 84.55  ? 4   GLN L OE1 1 
ATOM 2963 N NE2 . GLN D 4 3   ? 161.331 142.044 181.317 1.00 84.55  ? 4   GLN L NE2 1 
ATOM 2964 N N   . MET D 4 4   ? 160.572 142.279 177.895 1.00 82.18  ? 5   MET L N   1 
ATOM 2965 C CA  . MET D 4 4   ? 159.887 143.488 177.462 1.00 82.18  ? 5   MET L CA  1 
ATOM 2966 C C   . MET D 4 4   ? 160.283 144.645 178.370 1.00 82.18  ? 5   MET L C   1 
ATOM 2967 O O   . MET D 4 4   ? 160.298 144.499 179.598 1.00 82.18  ? 5   MET L O   1 
ATOM 2968 C CB  . MET D 4 4   ? 158.374 143.293 177.476 1.00 82.18  ? 5   MET L CB  1 
ATOM 2969 C CG  . MET D 4 4   ? 157.926 142.067 176.719 1.00 82.18  ? 5   MET L CG  1 
ATOM 2970 S SD  . MET D 4 4   ? 158.441 142.118 174.999 1.00 82.18  ? 5   MET L SD  1 
ATOM 2971 C CE  . MET D 4 4   ? 157.208 143.222 174.334 1.00 82.18  ? 5   MET L CE  1 
ATOM 2972 N N   . THR D 4 5   ? 160.610 145.784 177.770 1.00 78.18  ? 6   THR L N   1 
ATOM 2973 C CA  . THR D 4 5   ? 161.048 146.958 178.512 1.00 78.18  ? 6   THR L CA  1 
ATOM 2974 C C   . THR D 4 5   ? 160.150 148.133 178.167 1.00 78.18  ? 6   THR L C   1 
ATOM 2975 O O   . THR D 4 5   ? 159.874 148.379 176.991 1.00 78.18  ? 6   THR L O   1 
ATOM 2976 C CB  . THR D 4 5   ? 162.507 147.307 178.198 1.00 78.18  ? 6   THR L CB  1 
ATOM 2977 O OG1 . THR D 4 5   ? 163.341 146.172 178.455 1.00 78.18  ? 6   THR L OG1 1 
ATOM 2978 C CG2 . THR D 4 5   ? 162.973 148.472 179.057 1.00 78.18  ? 6   THR L CG2 1 
ATOM 2979 N N   . GLN D 4 6   ? 159.694 148.851 179.190 1.00 73.01  ? 7   GLN L N   1 
ATOM 2980 C CA  . GLN D 4 6   ? 158.948 150.088 179.011 1.00 73.01  ? 7   GLN L CA  1 
ATOM 2981 C C   . GLN D 4 6   ? 159.677 151.239 179.690 1.00 73.01  ? 7   GLN L C   1 
ATOM 2982 O O   . GLN D 4 6   ? 160.138 151.106 180.831 1.00 73.01  ? 7   GLN L O   1 
ATOM 2983 C CB  . GLN D 4 6   ? 157.530 149.970 179.563 1.00 73.01  ? 7   GLN L CB  1 
ATOM 2984 C CG  . GLN D 4 6   ? 156.675 148.985 178.812 1.00 73.01  ? 7   GLN L CG  1 
ATOM 2985 C CD  . GLN D 4 6   ? 155.290 148.844 179.397 1.00 73.01  ? 7   GLN L CD  1 
ATOM 2986 O OE1 . GLN D 4 6   ? 155.081 148.096 180.349 1.00 73.01  ? 7   GLN L OE1 1 
ATOM 2987 N NE2 . GLN D 4 6   ? 154.331 149.550 178.823 1.00 73.01  ? 7   GLN L NE2 1 
ATOM 2988 N N   . SER D 4 7   ? 159.813 152.347 178.969 1.00 77.33  ? 8   SER L N   1 
ATOM 2989 C CA  . SER D 4 7   ? 160.377 153.597 179.469 1.00 77.33  ? 8   SER L CA  1 
ATOM 2990 C C   . SER D 4 7   ? 159.378 154.509 180.186 1.00 77.33  ? 8   SER L C   1 
ATOM 2991 O O   . SER D 4 7   ? 159.691 155.014 181.273 1.00 77.33  ? 8   SER L O   1 
ATOM 2992 C CB  . SER D 4 7   ? 161.038 154.358 178.319 1.00 77.33  ? 8   SER L CB  1 
ATOM 2993 O OG  . SER D 4 7   ? 162.040 153.566 177.706 1.00 77.33  ? 8   SER L OG  1 
ATOM 2994 N N   . PRO D 4 8   ? 158.182 154.782 179.612 1.00 72.32  ? 9   PRO L N   1 
ATOM 2995 C CA  . PRO D 4 8   ? 157.305 155.807 180.229 1.00 72.32  ? 9   PRO L CA  1 
ATOM 2996 C C   . PRO D 4 8   ? 156.483 155.275 181.398 1.00 72.32  ? 9   PRO L C   1 
ATOM 2997 O O   . PRO D 4 8   ? 155.260 155.139 181.336 1.00 72.32  ? 9   PRO L O   1 
ATOM 2998 C CB  . PRO D 4 8   ? 156.431 156.236 179.046 1.00 72.32  ? 9   PRO L CB  1 
ATOM 2999 C CG  . PRO D 4 8   ? 156.293 154.988 178.239 1.00 72.32  ? 9   PRO L CG  1 
ATOM 3000 C CD  . PRO D 4 8   ? 157.596 154.252 178.363 1.00 72.32  ? 9   PRO L CD  1 
ATOM 3001 N N   . SER D 4 9   ? 157.163 154.996 182.512 1.00 73.10  ? 10  SER L N   1 
ATOM 3002 C CA  . SER D 4 9   ? 156.496 154.428 183.681 1.00 73.10  ? 10  SER L CA  1 
ATOM 3003 C C   . SER D 4 9   ? 155.405 155.336 184.233 1.00 73.10  ? 10  SER L C   1 
ATOM 3004 O O   . SER D 4 9   ? 154.451 154.844 184.845 1.00 73.10  ? 10  SER L O   1 
ATOM 3005 C CB  . SER D 4 9   ? 157.518 154.131 184.774 1.00 73.10  ? 10  SER L CB  1 
ATOM 3006 O OG  . SER D 4 9   ? 158.151 155.321 185.208 1.00 73.10  ? 10  SER L OG  1 
ATOM 3007 N N   . SER D 4 10  ? 155.517 156.650 184.031 1.00 73.05  ? 11  SER L N   1 
ATOM 3008 C CA  . SER D 4 10  ? 154.555 157.606 184.568 1.00 73.05  ? 11  SER L CA  1 
ATOM 3009 C C   . SER D 4 10  ? 154.227 158.623 183.486 1.00 73.05  ? 11  SER L C   1 
ATOM 3010 O O   . SER D 4 10  ? 155.114 159.344 183.022 1.00 73.05  ? 11  SER L O   1 
ATOM 3011 C CB  . SER D 4 10  ? 155.111 158.299 185.818 1.00 73.05  ? 11  SER L CB  1 
ATOM 3012 O OG  . SER D 4 10  ? 154.139 159.140 186.408 1.00 73.05  ? 11  SER L OG  1 
ATOM 3013 N N   . LEU D 4 11  ? 152.959 158.679 183.083 1.00 79.11  ? 12  LEU L N   1 
ATOM 3014 C CA  . LEU D 4 11  ? 152.514 159.543 181.996 1.00 79.11  ? 12  LEU L CA  1 
ATOM 3015 C C   . LEU D 4 11  ? 151.408 160.454 182.508 1.00 79.11  ? 12  LEU L C   1 
ATOM 3016 O O   . LEU D 4 11  ? 150.333 159.976 182.885 1.00 79.11  ? 12  LEU L O   1 
ATOM 3017 C CB  . LEU D 4 11  ? 152.030 158.712 180.805 1.00 79.11  ? 12  LEU L CB  1 
ATOM 3018 C CG  . LEU D 4 11  ? 151.690 159.401 179.480 1.00 79.11  ? 12  LEU L CG  1 
ATOM 3019 C CD1 . LEU D 4 11  ? 151.943 158.448 178.324 1.00 79.11  ? 12  LEU L CD1 1 
ATOM 3020 C CD2 . LEU D 4 11  ? 150.246 159.888 179.445 1.00 79.11  ? 12  LEU L CD2 1 
ATOM 3021 N N   . SER D 4 12  ? 151.665 161.760 182.501 1.00 80.64  ? 13  SER L N   1 
ATOM 3022 C CA  . SER D 4 12  ? 150.707 162.757 182.963 1.00 80.64  ? 13  SER L CA  1 
ATOM 3023 C C   . SER D 4 12  ? 150.066 163.446 181.766 1.00 80.64  ? 13  SER L C   1 
ATOM 3024 O O   . SER D 4 12  ? 150.762 164.081 180.967 1.00 80.64  ? 13  SER L O   1 
ATOM 3025 C CB  . SER D 4 12  ? 151.391 163.784 183.858 1.00 80.64  ? 13  SER L CB  1 
ATOM 3026 O OG  . SER D 4 12  ? 152.243 163.153 184.795 1.00 80.64  ? 13  SER L OG  1 
ATOM 3027 N N   . ALA D 4 13  ? 148.744 163.343 181.661 1.00 81.00  ? 14  ALA L N   1 
ATOM 3028 C CA  . ALA D 4 13  ? 148.019 163.941 180.554 1.00 81.00  ? 14  ALA L CA  1 
ATOM 3029 C C   . ALA D 4 13  ? 146.594 164.231 180.994 1.00 81.00  ? 14  ALA L C   1 
ATOM 3030 O O   . ALA D 4 13  ? 146.069 163.603 181.915 1.00 81.00  ? 14  ALA L O   1 
ATOM 3031 C CB  . ALA D 4 13  ? 148.024 163.035 179.319 1.00 81.00  ? 14  ALA L CB  1 
ATOM 3032 N N   . SER D 4 14  ? 145.970 165.187 180.321 1.00 86.25  ? 15  SER L N   1 
ATOM 3033 C CA  . SER D 4 14  ? 144.615 165.602 180.642 1.00 86.25  ? 15  SER L CA  1 
ATOM 3034 C C   . SER D 4 14  ? 143.623 164.991 179.662 1.00 86.25  ? 15  SER L C   1 
ATOM 3035 O O   . SER D 4 14  ? 143.993 164.437 178.628 1.00 86.25  ? 15  SER L O   1 
ATOM 3036 C CB  . SER D 4 14  ? 144.507 167.130 180.636 1.00 86.25  ? 15  SER L CB  1 
ATOM 3037 O OG  . SER D 4 14  ? 144.966 167.668 179.409 1.00 86.25  ? 15  SER L OG  1 
ATOM 3038 N N   . VAL D 4 15  ? 142.339 165.107 180.004 1.00 82.65  ? 16  VAL L N   1 
ATOM 3039 C CA  . VAL D 4 15  ? 141.294 164.533 179.169 1.00 82.65  ? 16  VAL L CA  1 
ATOM 3040 C C   . VAL D 4 15  ? 141.321 165.188 177.799 1.00 82.65  ? 16  VAL L C   1 
ATOM 3041 O O   . VAL D 4 15  ? 141.308 166.419 177.676 1.00 82.65  ? 16  VAL L O   1 
ATOM 3042 C CB  . VAL D 4 15  ? 139.923 164.697 179.836 1.00 82.65  ? 16  VAL L CB  1 
ATOM 3043 C CG1 . VAL D 4 15  ? 138.823 164.252 178.892 1.00 82.65  ? 16  VAL L CG1 1 
ATOM 3044 C CG2 . VAL D 4 15  ? 139.869 163.905 181.131 1.00 82.65  ? 16  VAL L CG2 1 
ATOM 3045 N N   . GLY D 4 16  ? 141.356 164.361 176.757 1.00 87.85  ? 17  GLY L N   1 
ATOM 3046 C CA  . GLY D 4 16  ? 141.426 164.812 175.389 1.00 87.85  ? 17  GLY L CA  1 
ATOM 3047 C C   . GLY D 4 16  ? 142.799 164.715 174.758 1.00 87.85  ? 17  GLY L C   1 
ATOM 3048 O O   . GLY D 4 16  ? 142.894 164.690 173.527 1.00 87.85  ? 17  GLY L O   1 
ATOM 3049 N N   . ASP D 4 17  ? 143.859 164.654 175.559 1.00 89.45  ? 18  ASP L N   1 
ATOM 3050 C CA  . ASP D 4 17  ? 145.197 164.531 175.003 1.00 89.45  ? 18  ASP L CA  1 
ATOM 3051 C C   . ASP D 4 17  ? 145.394 163.164 174.357 1.00 89.45  ? 18  ASP L C   1 
ATOM 3052 O O   . ASP D 4 17  ? 144.850 162.153 174.805 1.00 89.45  ? 18  ASP L O   1 
ATOM 3053 C CB  . ASP D 4 17  ? 146.258 164.741 176.083 1.00 89.45  ? 18  ASP L CB  1 
ATOM 3054 C CG  . ASP D 4 17  ? 146.253 166.146 176.638 1.00 89.45  ? 18  ASP L CG  1 
ATOM 3055 O OD1 . ASP D 4 17  ? 145.694 167.047 175.978 1.00 89.45  ? 18  ASP L OD1 1 
ATOM 3056 O OD2 . ASP D 4 17  ? 146.814 166.352 177.733 1.00 89.45  ? 18  ASP L OD2 1 
ATOM 3057 N N   . ARG D 4 18  ? 146.187 163.142 173.294 1.00 90.52  ? 19  ARG L N   1 
ATOM 3058 C CA  . ARG D 4 18  ? 146.606 161.900 172.669 1.00 90.52  ? 19  ARG L CA  1 
ATOM 3059 C C   . ARG D 4 18  ? 147.875 161.415 173.354 1.00 90.52  ? 19  ARG L C   1 
ATOM 3060 O O   . ARG D 4 18  ? 148.859 162.157 173.439 1.00 90.52  ? 19  ARG L O   1 
ATOM 3061 C CB  . ARG D 4 18  ? 146.847 162.104 171.176 1.00 90.52  ? 19  ARG L CB  1 
ATOM 3062 C CG  . ARG D 4 18  ? 147.472 160.917 170.474 1.00 90.52  ? 19  ARG L CG  1 
ATOM 3063 C CD  . ARG D 4 18  ? 147.468 161.124 168.972 1.00 90.52  ? 19  ARG L CD  1 
ATOM 3064 N NE  . ARG D 4 18  ? 146.112 161.302 168.470 1.00 90.52  ? 19  ARG L NE  1 
ATOM 3065 C CZ  . ARG D 4 18  ? 145.809 161.590 167.212 1.00 90.52  ? 19  ARG L CZ  1 
ATOM 3066 N NH1 . ARG D 4 18  ? 146.747 161.738 166.291 1.00 90.52  ? 19  ARG L NH1 1 
ATOM 3067 N NH2 . ARG D 4 18  ? 144.532 161.734 166.870 1.00 90.52  ? 19  ARG L NH2 1 
ATOM 3068 N N   . VAL D 4 19  ? 147.857 160.173 173.835 1.00 81.68  ? 20  VAL L N   1 
ATOM 3069 C CA  . VAL D 4 19  ? 148.964 159.675 174.645 1.00 81.68  ? 20  VAL L CA  1 
ATOM 3070 C C   . VAL D 4 19  ? 149.571 158.454 173.970 1.00 81.68  ? 20  VAL L C   1 
ATOM 3071 O O   . VAL D 4 19  ? 148.894 157.712 173.253 1.00 81.68  ? 20  VAL L O   1 
ATOM 3072 C CB  . VAL D 4 19  ? 148.534 159.346 176.094 1.00 81.68  ? 20  VAL L CB  1 
ATOM 3073 C CG1 . VAL D 4 19  ? 147.643 160.447 176.655 1.00 81.68  ? 20  VAL L CG1 1 
ATOM 3074 C CG2 . VAL D 4 19  ? 147.839 158.003 176.165 1.00 81.68  ? 20  VAL L CG2 1 
ATOM 3075 N N   . THR D 4 20  ? 150.870 158.261 174.199 1.00 74.48  ? 21  THR L N   1 
ATOM 3076 C CA  . THR D 4 20  ? 151.640 157.211 173.550 1.00 74.48  ? 21  THR L CA  1 
ATOM 3077 C C   . THR D 4 20  ? 152.548 156.529 174.564 1.00 74.48  ? 21  THR L C   1 
ATOM 3078 O O   . THR D 4 20  ? 153.247 157.199 175.330 1.00 74.48  ? 21  THR L O   1 
ATOM 3079 C CB  . THR D 4 20  ? 152.464 157.787 172.390 1.00 74.48  ? 21  THR L CB  1 
ATOM 3080 O OG1 . THR D 4 20  ? 151.602 158.039 171.275 1.00 74.48  ? 21  THR L OG1 1 
ATOM 3081 C CG2 . THR D 4 20  ? 153.568 156.834 171.968 1.00 74.48  ? 21  THR L CG2 1 
ATOM 3082 N N   . ILE D 4 21  ? 152.529 155.196 174.559 1.00 67.32  ? 22  ILE L N   1 
ATOM 3083 C CA  . ILE D 4 21  ? 153.383 154.360 175.391 1.00 67.32  ? 22  ILE L CA  1 
ATOM 3084 C C   . ILE D 4 21  ? 154.166 153.438 174.469 1.00 67.32  ? 22  ILE L C   1 
ATOM 3085 O O   . ILE D 4 21  ? 153.620 152.919 173.493 1.00 67.32  ? 22  ILE L O   1 
ATOM 3086 C CB  . ILE D 4 21  ? 152.563 153.538 176.409 1.00 67.32  ? 22  ILE L CB  1 
ATOM 3087 C CG1 . ILE D 4 21  ? 151.540 154.421 177.121 1.00 67.32  ? 22  ILE L CG1 1 
ATOM 3088 C CG2 . ILE D 4 21  ? 153.477 152.862 177.407 1.00 67.32  ? 22  ILE L CG2 1 
ATOM 3089 C CD1 . ILE D 4 21  ? 150.110 154.153 176.696 1.00 67.32  ? 22  ILE L CD1 1 
ATOM 3090 N N   . THR D 4 22  ? 155.447 153.254 174.759 1.00 71.83  ? 23  THR L N   1 
ATOM 3091 C CA  . THR D 4 22  ? 156.299 152.395 173.952 1.00 71.83  ? 23  THR L CA  1 
ATOM 3092 C C   . THR D 4 22  ? 156.708 151.167 174.753 1.00 71.83  ? 23  THR L C   1 
ATOM 3093 O O   . THR D 4 22  ? 156.611 151.136 175.982 1.00 71.83  ? 23  THR L O   1 
ATOM 3094 C CB  . THR D 4 22  ? 157.548 153.139 173.469 1.00 71.83  ? 23  THR L CB  1 
ATOM 3095 O OG1 . THR D 4 22  ? 158.380 153.460 174.591 1.00 71.83  ? 23  THR L OG1 1 
ATOM 3096 C CG2 . THR D 4 22  ? 157.160 154.418 172.742 1.00 71.83  ? 23  THR L CG2 1 
ATOM 3097 N N   . CYS D 4 23  ? 157.159 150.143 174.034 1.00 74.32  ? 24  CYS L N   1 
ATOM 3098 C CA  . CYS D 4 23  ? 157.649 148.923 174.664 1.00 74.32  ? 24  CYS L CA  1 
ATOM 3099 C C   . CYS D 4 23  ? 158.576 148.223 173.686 1.00 74.32  ? 24  CYS L C   1 
ATOM 3100 O O   . CYS D 4 23  ? 158.228 148.046 172.517 1.00 74.32  ? 24  CYS L O   1 
ATOM 3101 C CB  . CYS D 4 23  ? 156.482 148.018 175.072 1.00 74.32  ? 24  CYS L CB  1 
ATOM 3102 S SG  . CYS D 4 23  ? 156.899 146.405 175.762 1.00 74.32  ? 24  CYS L SG  1 
ATOM 3103 N N   . ARG D 4 24  ? 159.752 147.835 174.158 1.00 82.22  ? 25  ARG L N   1 
ATOM 3104 C CA  . ARG D 4 24  ? 160.761 147.206 173.319 1.00 82.22  ? 25  ARG L CA  1 
ATOM 3105 C C   . ARG D 4 24  ? 160.968 145.758 173.738 1.00 82.22  ? 25  ARG L C   1 
ATOM 3106 O O   . ARG D 4 24  ? 161.130 145.464 174.928 1.00 82.22  ? 25  ARG L O   1 
ATOM 3107 C CB  . ARG D 4 24  ? 162.082 147.968 173.388 1.00 82.22  ? 25  ARG L CB  1 
ATOM 3108 C CG  . ARG D 4 24  ? 163.240 147.244 172.734 1.00 82.22  ? 25  ARG L CG  1 
ATOM 3109 C CD  . ARG D 4 24  ? 164.476 148.118 172.691 1.00 82.22  ? 25  ARG L CD  1 
ATOM 3110 N NE  . ARG D 4 24  ? 164.293 149.262 171.807 1.00 82.22  ? 25  ARG L NE  1 
ATOM 3111 C CZ  . ARG D 4 24  ? 165.234 150.153 171.529 1.00 82.22  ? 25  ARG L CZ  1 
ATOM 3112 N NH1 . ARG D 4 24  ? 166.445 150.068 172.057 1.00 82.22  ? 25  ARG L NH1 1 
ATOM 3113 N NH2 . ARG D 4 24  ? 164.955 151.153 170.697 1.00 82.22  ? 25  ARG L NH2 1 
ATOM 3114 N N   . ALA D 4 25  ? 160.955 144.862 172.756 1.00 75.29  ? 26  ALA L N   1 
ATOM 3115 C CA  . ALA D 4 25  ? 161.291 143.464 172.967 1.00 75.29  ? 26  ALA L CA  1 
ATOM 3116 C C   . ALA D 4 25  ? 162.786 143.261 172.756 1.00 75.29  ? 26  ALA L C   1 
ATOM 3117 O O   . ALA D 4 25  ? 163.384 143.858 171.859 1.00 75.29  ? 26  ALA L O   1 
ATOM 3118 C CB  . ALA D 4 25  ? 160.496 142.568 172.018 1.00 75.29  ? 26  ALA L CB  1 
ATOM 3119 N N   . SER D 4 26  ? 163.387 142.416 173.593 1.00 77.73  ? 27  SER L N   1 
ATOM 3120 C CA  . SER D 4 26  ? 164.831 142.225 173.572 1.00 77.73  ? 27  SER L CA  1 
ATOM 3121 C C   . SER D 4 26  ? 165.308 141.336 172.432 1.00 77.73  ? 27  SER L C   1 
ATOM 3122 O O   . SER D 4 26  ? 166.514 141.295 172.169 1.00 77.73  ? 27  SER L O   1 
ATOM 3123 C CB  . SER D 4 26  ? 165.300 141.636 174.902 1.00 77.73  ? 27  SER L CB  1 
ATOM 3124 O OG  . SER D 4 26  ? 164.752 140.344 175.105 1.00 77.73  ? 27  SER L OG  1 
ATOM 3125 N N   . GLN D 4 27  ? 164.410 140.627 171.755 1.00 75.35  ? 28  GLN L N   1 
ATOM 3126 C CA  . GLN D 4 27  ? 164.780 139.722 170.677 1.00 75.35  ? 28  GLN L CA  1 
ATOM 3127 C C   . GLN D 4 27  ? 164.059 140.106 169.396 1.00 75.35  ? 28  GLN L C   1 
ATOM 3128 O O   . GLN D 4 27  ? 163.095 140.874 169.401 1.00 75.35  ? 28  GLN L O   1 
ATOM 3129 C CB  . GLN D 4 27  ? 164.457 138.263 171.025 1.00 75.35  ? 28  GLN L CB  1 
ATOM 3130 C CG  . GLN D 4 27  ? 165.354 137.657 172.081 1.00 75.35  ? 28  GLN L CG  1 
ATOM 3131 C CD  . GLN D 4 27  ? 165.221 136.154 172.158 1.00 75.35  ? 28  GLN L CD  1 
ATOM 3132 O OE1 . GLN D 4 27  ? 164.921 135.496 171.166 1.00 75.35  ? 28  GLN L OE1 1 
ATOM 3133 N NE2 . GLN D 4 27  ? 165.443 135.601 173.344 1.00 75.35  ? 28  GLN L NE2 1 
ATOM 3134 N N   . SER D 4 28  ? 164.550 139.553 168.285 1.00 72.54  ? 29  SER L N   1 
ATOM 3135 C CA  . SER D 4 28  ? 163.930 139.752 166.983 1.00 72.54  ? 29  SER L CA  1 
ATOM 3136 C C   . SER D 4 28  ? 162.653 138.933 166.892 1.00 72.54  ? 29  SER L C   1 
ATOM 3137 O O   . SER D 4 28  ? 162.587 137.945 166.155 1.00 72.54  ? 29  SER L O   1 
ATOM 3138 C CB  . SER D 4 28  ? 164.895 139.368 165.862 1.00 72.54  ? 29  SER L CB  1 
ATOM 3139 O OG  . SER D 4 28  ? 166.087 140.128 165.934 1.00 72.54  ? 29  SER L OG  1 
ATOM 3140 N N   . VAL D 4 29  ? 161.642 139.340 167.636 1.00 68.54  ? 30  VAL L N   1 
ATOM 3141 C CA  . VAL D 4 29  ? 160.400 138.601 167.739 1.00 68.54  ? 30  VAL L CA  1 
ATOM 3142 C C   . VAL D 4 29  ? 159.442 139.060 166.648 1.00 68.54  ? 30  VAL L C   1 
ATOM 3143 O O   . VAL D 4 29  ? 159.620 140.109 166.023 1.00 68.54  ? 30  VAL L O   1 
ATOM 3144 C CB  . VAL D 4 29  ? 159.778 138.787 169.127 1.00 68.54  ? 30  VAL L CB  1 
ATOM 3145 C CG1 . VAL D 4 29  ? 160.843 138.645 170.193 1.00 68.54  ? 30  VAL L CG1 1 
ATOM 3146 C CG2 . VAL D 4 29  ? 159.136 140.151 169.208 1.00 68.54  ? 30  VAL L CG2 1 
ATOM 3147 N N   . SER D 4 30  ? 158.403 138.260 166.422 1.00 67.47  ? 31  SER L N   1 
ATOM 3148 C CA  . SER D 4 30  ? 157.341 138.602 165.483 1.00 67.47  ? 31  SER L CA  1 
ATOM 3149 C C   . SER D 4 30  ? 156.374 139.568 166.156 1.00 67.47  ? 31  SER L C   1 
ATOM 3150 O O   . SER D 4 30  ? 156.652 140.111 167.224 1.00 67.47  ? 31  SER L O   1 
ATOM 3151 C CB  . SER D 4 30  ? 156.629 137.349 165.000 1.00 67.47  ? 31  SER L CB  1 
ATOM 3152 O OG  . SER D 4 30  ? 155.805 137.624 163.883 1.00 67.47  ? 31  SER L OG  1 
ATOM 3153 N N   . SER D 4 31  ? 155.210 139.778 165.544 1.00 68.41  ? 32  SER L N   1 
ATOM 3154 C CA  . SER D 4 31  ? 154.207 140.693 166.068 1.00 68.41  ? 32  SER L CA  1 
ATOM 3155 C C   . SER D 4 31  ? 153.481 140.148 167.290 1.00 68.41  ? 32  SER L C   1 
ATOM 3156 O O   . SER D 4 31  ? 152.405 140.643 167.626 1.00 68.41  ? 32  SER L O   1 
ATOM 3157 C CB  . SER D 4 31  ? 153.175 141.024 164.990 1.00 68.41  ? 32  SER L CB  1 
ATOM 3158 O OG  . SER D 4 31  ? 152.282 139.947 164.803 1.00 68.41  ? 32  SER L OG  1 
ATOM 3159 N N   . ALA D 4 32  ? 154.030 139.125 167.947 1.00 60.96  ? 33  ALA L N   1 
ATOM 3160 C CA  . ALA D 4 32  ? 153.414 138.556 169.149 1.00 60.96  ? 33  ALA L CA  1 
ATOM 3161 C C   . ALA D 4 32  ? 153.683 139.433 170.374 1.00 60.96  ? 33  ALA L C   1 
ATOM 3162 O O   . ALA D 4 32  ? 154.385 139.041 171.298 1.00 60.96  ? 33  ALA L O   1 
ATOM 3163 C CB  . ALA D 4 32  ? 153.938 137.149 169.397 1.00 60.96  ? 33  ALA L CB  1 
ATOM 3164 N N   . VAL D 4 33  ? 153.101 140.637 170.378 1.00 59.26  ? 34  VAL L N   1 
ATOM 3165 C CA  . VAL D 4 33  ? 153.135 141.520 171.541 1.00 59.26  ? 34  VAL L CA  1 
ATOM 3166 C C   . VAL D 4 33  ? 151.721 142.011 171.799 1.00 59.26  ? 34  VAL L C   1 
ATOM 3167 O O   . VAL D 4 33  ? 150.970 142.288 170.859 1.00 59.26  ? 34  VAL L O   1 
ATOM 3168 C CB  . VAL D 4 33  ? 154.110 142.699 171.349 1.00 59.26  ? 34  VAL L CB  1 
ATOM 3169 C CG1 . VAL D 4 33  ? 153.952 143.723 172.460 1.00 59.26  ? 34  VAL L CG1 1 
ATOM 3170 C CG2 . VAL D 4 33  ? 155.532 142.184 171.315 1.00 59.26  ? 34  VAL L CG2 1 
ATOM 3171 N N   . ALA D 4 34  ? 151.349 142.080 173.072 1.00 58.02  ? 35  ALA L N   1 
ATOM 3172 C CA  . ALA D 4 34  ? 150.000 142.453 173.462 1.00 58.02  ? 35  ALA L CA  1 
ATOM 3173 C C   . ALA D 4 34  ? 150.033 143.571 174.491 1.00 58.02  ? 35  ALA L C   1 
ATOM 3174 O O   . ALA D 4 34  ? 151.003 143.726 175.238 1.00 58.02  ? 35  ALA L O   1 
ATOM 3175 C CB  . ALA D 4 34  ? 149.223 141.254 174.019 1.00 58.02  ? 35  ALA L CB  1 
ATOM 3176 N N   . TRP D 4 35  ? 148.956 144.352 174.509 1.00 58.52  ? 36  TRP L N   1 
ATOM 3177 C CA  . TRP D 4 35  ? 148.763 145.444 175.453 1.00 58.52  ? 36  TRP L CA  1 
ATOM 3178 C C   . TRP D 4 35  ? 147.497 145.206 176.257 1.00 58.52  ? 36  TRP L C   1 
ATOM 3179 O O   . TRP D 4 35  ? 146.431 144.971 175.683 1.00 58.52  ? 36  TRP L O   1 
ATOM 3180 C CB  . TRP D 4 35  ? 148.656 146.796 174.740 1.00 58.52  ? 36  TRP L CB  1 
ATOM 3181 C CG  . TRP D 4 35  ? 149.890 147.210 174.031 1.00 58.52  ? 36  TRP L CG  1 
ATOM 3182 C CD1 . TRP D 4 35  ? 150.194 146.994 172.723 1.00 58.52  ? 36  TRP L CD1 1 
ATOM 3183 C CD2 . TRP D 4 35  ? 150.994 147.929 174.587 1.00 58.52  ? 36  TRP L CD2 1 
ATOM 3184 N NE1 . TRP D 4 35  ? 151.422 147.525 172.430 1.00 58.52  ? 36  TRP L NE1 1 
ATOM 3185 C CE2 . TRP D 4 35  ? 151.934 148.108 173.558 1.00 58.52  ? 36  TRP L CE2 1 
ATOM 3186 C CE3 . TRP D 4 35  ? 151.279 148.436 175.856 1.00 58.52  ? 36  TRP L CE3 1 
ATOM 3187 C CZ2 . TRP D 4 35  ? 153.136 148.770 173.757 1.00 58.52  ? 36  TRP L CZ2 1 
ATOM 3188 C CZ3 . TRP D 4 35  ? 152.470 149.095 176.050 1.00 58.52  ? 36  TRP L CZ3 1 
ATOM 3189 C CH2 . TRP D 4 35  ? 153.384 149.258 175.007 1.00 58.52  ? 36  TRP L CH2 1 
ATOM 3190 N N   . TYR D 4 36  ? 147.617 145.324 177.576 1.00 55.87  ? 37  TYR L N   1 
ATOM 3191 C CA  . TYR D 4 36  ? 146.515 145.147 178.513 1.00 55.87  ? 37  TYR L CA  1 
ATOM 3192 C C   . TYR D 4 36  ? 146.354 146.390 179.375 1.00 55.87  ? 37  TYR L C   1 
ATOM 3193 O O   . TYR D 4 36  ? 147.331 147.073 179.697 1.00 55.87  ? 37  TYR L O   1 
ATOM 3194 C CB  . TYR D 4 36  ? 146.730 143.943 179.444 1.00 55.87  ? 37  TYR L CB  1 
ATOM 3195 C CG  . TYR D 4 36  ? 146.998 142.639 178.741 1.00 55.87  ? 37  TYR L CG  1 
ATOM 3196 C CD1 . TYR D 4 36  ? 148.291 142.265 178.403 1.00 55.87  ? 37  TYR L CD1 1 
ATOM 3197 C CD2 . TYR D 4 36  ? 145.964 141.776 178.430 1.00 55.87  ? 37  TYR L CD2 1 
ATOM 3198 C CE1 . TYR D 4 36  ? 148.539 141.078 177.764 1.00 55.87  ? 37  TYR L CE1 1 
ATOM 3199 C CE2 . TYR D 4 36  ? 146.205 140.583 177.790 1.00 55.87  ? 37  TYR L CE2 1 
ATOM 3200 C CZ  . TYR D 4 36  ? 147.493 140.238 177.462 1.00 55.87  ? 37  TYR L CZ  1 
ATOM 3201 O OH  . TYR D 4 36  ? 147.739 139.048 176.824 1.00 55.87  ? 37  TYR L OH  1 
ATOM 3202 N N   . GLN D 4 37  ? 145.110 146.661 179.754 1.00 60.04  ? 38  GLN L N   1 
ATOM 3203 C CA  . GLN D 4 37  ? 144.762 147.737 180.674 1.00 60.04  ? 38  GLN L CA  1 
ATOM 3204 C C   . GLN D 4 37  ? 144.236 147.155 181.979 1.00 60.04  ? 38  GLN L C   1 
ATOM 3205 O O   . GLN D 4 37  ? 143.329 146.319 181.970 1.00 60.04  ? 38  GLN L O   1 
ATOM 3206 C CB  . GLN D 4 37  ? 143.707 148.661 180.065 1.00 60.04  ? 38  GLN L CB  1 
ATOM 3207 C CG  . GLN D 4 37  ? 143.162 149.708 181.020 1.00 60.04  ? 38  GLN L CG  1 
ATOM 3208 C CD  . GLN D 4 37  ? 141.890 150.357 180.511 1.00 60.04  ? 38  GLN L CD  1 
ATOM 3209 O OE1 . GLN D 4 37  ? 140.817 149.755 180.541 1.00 60.04  ? 38  GLN L OE1 1 
ATOM 3210 N NE2 . GLN D 4 37  ? 142.002 151.593 180.041 1.00 60.04  ? 38  GLN L NE2 1 
ATOM 3211 N N   . GLN D 4 38  ? 144.780 147.622 183.095 1.00 63.57  ? 39  GLN L N   1 
ATOM 3212 C CA  . GLN D 4 38  ? 144.377 147.167 184.413 1.00 63.57  ? 39  GLN L CA  1 
ATOM 3213 C C   . GLN D 4 38  ? 144.096 148.359 185.313 1.00 63.57  ? 39  GLN L C   1 
ATOM 3214 O O   . GLN D 4 38  ? 144.861 149.331 185.337 1.00 63.57  ? 39  GLN L O   1 
ATOM 3215 C CB  . GLN D 4 38  ? 145.451 146.282 185.059 1.00 63.57  ? 39  GLN L CB  1 
ATOM 3216 C CG  . GLN D 4 38  ? 145.060 145.761 186.433 1.00 63.57  ? 39  GLN L CG  1 
ATOM 3217 C CD  . GLN D 4 38  ? 146.203 145.097 187.167 1.00 63.57  ? 39  GLN L CD  1 
ATOM 3218 O OE1 . GLN D 4 38  ? 147.370 145.389 186.918 1.00 63.57  ? 39  GLN L OE1 1 
ATOM 3219 N NE2 . GLN D 4 38  ? 145.871 144.196 188.081 1.00 63.57  ? 39  GLN L NE2 1 
ATOM 3220 N N   . LYS D 4 39  ? 143.004 148.273 186.050 1.00 72.19  ? 40  LYS L N   1 
ATOM 3221 C CA  . LYS D 4 39  ? 142.621 149.193 187.102 1.00 72.19  ? 40  LYS L CA  1 
ATOM 3222 C C   . LYS D 4 39  ? 142.877 148.547 188.456 1.00 72.19  ? 40  LYS L C   1 
ATOM 3223 O O   . LYS D 4 39  ? 142.834 147.320 188.577 1.00 72.19  ? 40  LYS L O   1 
ATOM 3224 C CB  . LYS D 4 39  ? 141.141 149.571 186.981 1.00 72.19  ? 40  LYS L CB  1 
ATOM 3225 C CG  . LYS D 4 39  ? 140.768 150.181 185.642 1.00 108.28 ? 40  LYS L CG  1 
ATOM 3226 C CD  . LYS D 4 39  ? 139.286 150.487 185.560 1.00 108.28 ? 40  LYS L CD  1 
ATOM 3227 C CE  . LYS D 4 39  ? 138.967 151.290 184.315 1.00 108.28 ? 40  LYS L CE  1 
ATOM 3228 N NZ  . LYS D 4 39  ? 139.759 152.546 184.280 1.00 108.28 ? 40  LYS L NZ  1 
ATOM 3229 N N   . PRO D 4 40  ? 143.174 149.335 189.488 1.00 79.65  ? 41  PRO L N   1 
ATOM 3230 C CA  . PRO D 4 40  ? 143.466 148.744 190.802 1.00 79.65  ? 41  PRO L CA  1 
ATOM 3231 C C   . PRO D 4 40  ? 142.318 147.876 191.297 1.00 79.65  ? 41  PRO L C   1 
ATOM 3232 O O   . PRO D 4 40  ? 141.149 148.265 191.244 1.00 79.65  ? 41  PRO L O   1 
ATOM 3233 C CB  . PRO D 4 40  ? 143.678 149.967 191.698 1.00 79.65  ? 41  PRO L CB  1 
ATOM 3234 C CG  . PRO D 4 40  ? 144.099 151.043 190.764 1.00 79.65  ? 41  PRO L CG  1 
ATOM 3235 C CD  . PRO D 4 40  ? 143.340 150.798 189.496 1.00 79.65  ? 41  PRO L CD  1 
ATOM 3236 N N   . GLY D 4 41  ? 142.666 146.687 191.782 1.00 81.84  ? 42  GLY L N   1 
ATOM 3237 C CA  . GLY D 4 41  ? 141.685 145.747 192.274 1.00 81.84  ? 42  GLY L CA  1 
ATOM 3238 C C   . GLY D 4 41  ? 141.010 144.896 191.221 1.00 81.84  ? 42  GLY L C   1 
ATOM 3239 O O   . GLY D 4 41  ? 140.156 144.073 191.573 1.00 81.84  ? 42  GLY L O   1 
ATOM 3240 N N   . LYS D 4 42  ? 141.355 145.060 189.946 1.00 77.70  ? 43  LYS L N   1 
ATOM 3241 C CA  . LYS D 4 42  ? 140.734 144.294 188.877 1.00 77.70  ? 43  LYS L CA  1 
ATOM 3242 C C   . LYS D 4 42  ? 141.793 143.609 188.023 1.00 77.70  ? 43  LYS L C   1 
ATOM 3243 O O   . LYS D 4 42  ? 142.947 144.041 187.961 1.00 77.70  ? 43  LYS L O   1 
ATOM 3244 C CB  . LYS D 4 42  ? 139.839 145.182 188.005 1.00 77.70  ? 43  LYS L CB  1 
ATOM 3245 C CG  . LYS D 4 42  ? 138.565 145.632 188.699 1.00 116.55 ? 43  LYS L CG  1 
ATOM 3246 C CD  . LYS D 4 42  ? 137.660 146.402 187.754 1.00 116.55 ? 43  LYS L CD  1 
ATOM 3247 C CE  . LYS D 4 42  ? 136.387 146.850 188.452 1.00 116.55 ? 43  LYS L CE  1 
ATOM 3248 N NZ  . LYS D 4 42  ? 135.518 147.654 187.549 1.00 116.55 ? 43  LYS L NZ  1 
ATOM 3249 N N   . ALA D 4 43  ? 141.387 142.516 187.383 1.00 69.60  ? 44  ALA L N   1 
ATOM 3250 C CA  . ALA D 4 43  ? 142.277 141.780 186.504 1.00 69.60  ? 44  ALA L CA  1 
ATOM 3251 C C   . ALA D 4 43  ? 142.518 142.558 185.212 1.00 69.60  ? 44  ALA L C   1 
ATOM 3252 O O   . ALA D 4 43  ? 141.639 143.287 184.745 1.00 69.60  ? 44  ALA L O   1 
ATOM 3253 C CB  . ALA D 4 43  ? 141.691 140.410 186.176 1.00 69.60  ? 44  ALA L CB  1 
ATOM 3254 N N   . PRO D 4 44  ? 143.700 142.411 184.609 1.00 60.57  ? 45  PRO L N   1 
ATOM 3255 C CA  . PRO D 4 44  ? 143.979 143.117 183.356 1.00 60.57  ? 45  PRO L CA  1 
ATOM 3256 C C   . PRO D 4 44  ? 143.016 142.702 182.256 1.00 60.57  ? 45  PRO L C   1 
ATOM 3257 O O   . PRO D 4 44  ? 142.498 141.585 182.241 1.00 60.57  ? 45  PRO L O   1 
ATOM 3258 C CB  . PRO D 4 44  ? 145.416 142.703 183.027 1.00 60.57  ? 45  PRO L CB  1 
ATOM 3259 C CG  . PRO D 4 44  ? 146.005 142.317 184.330 1.00 60.57  ? 45  PRO L CG  1 
ATOM 3260 C CD  . PRO D 4 44  ? 144.889 141.713 185.124 1.00 60.57  ? 45  PRO L CD  1 
ATOM 3261 N N   . LYS D 4 45  ? 142.763 143.630 181.341 1.00 62.93  ? 46  LYS L N   1 
ATOM 3262 C CA  . LYS D 4 45  ? 141.844 143.431 180.231 1.00 62.93  ? 46  LYS L CA  1 
ATOM 3263 C C   . LYS D 4 45  ? 142.579 143.661 178.918 1.00 62.93  ? 46  LYS L C   1 
ATOM 3264 O O   . LYS D 4 45  ? 143.307 144.648 178.777 1.00 62.93  ? 46  LYS L O   1 
ATOM 3265 C CB  . LYS D 4 45  ? 140.643 144.367 180.343 1.00 62.93  ? 46  LYS L CB  1 
ATOM 3266 C CG  . LYS D 4 45  ? 139.608 144.162 179.262 1.00 62.93  ? 46  LYS L CG  1 
ATOM 3267 C CD  . LYS D 4 45  ? 138.478 145.167 179.387 1.00 62.93  ? 46  LYS L CD  1 
ATOM 3268 C CE  . LYS D 4 45  ? 137.558 145.095 178.183 1.00 62.93  ? 46  LYS L CE  1 
ATOM 3269 N NZ  . LYS D 4 45  ? 136.509 146.148 178.220 1.00 62.93  ? 46  LYS L NZ  1 
ATOM 3270 N N   . LEU D 4 46  ? 142.389 142.750 177.966 1.00 59.92  ? 47  LEU L N   1 
ATOM 3271 C CA  . LEU D 4 46  ? 143.115 142.817 176.704 1.00 59.92  ? 47  LEU L CA  1 
ATOM 3272 C C   . LEU D 4 46  ? 142.671 144.017 175.879 1.00 59.92  ? 47  LEU L C   1 
ATOM 3273 O O   . LEU D 4 46  ? 141.478 144.199 175.617 1.00 59.92  ? 47  LEU L O   1 
ATOM 3274 C CB  . LEU D 4 46  ? 142.908 141.528 175.906 1.00 59.92  ? 47  LEU L CB  1 
ATOM 3275 C CG  . LEU D 4 46  ? 143.559 141.443 174.522 1.00 59.92  ? 47  LEU L CG  1 
ATOM 3276 C CD1 . LEU D 4 46  ? 145.075 141.515 174.607 1.00 59.92  ? 47  LEU L CD1 1 
ATOM 3277 C CD2 . LEU D 4 46  ? 143.126 140.177 173.814 1.00 59.92  ? 47  LEU L CD2 1 
ATOM 3278 N N   . LEU D 4 47  ? 143.635 144.834 175.456 1.00 58.87  ? 48  LEU L N   1 
ATOM 3279 C CA  . LEU D 4 47  ? 143.399 145.921 174.519 1.00 58.87  ? 48  LEU L CA  1 
ATOM 3280 C C   . LEU D 4 47  ? 143.901 145.570 173.121 1.00 58.87  ? 48  LEU L C   1 
ATOM 3281 O O   . LEU D 4 47  ? 143.132 145.591 172.157 1.00 58.87  ? 48  LEU L O   1 
ATOM 3282 C CB  . LEU D 4 47  ? 144.083 147.211 175.000 1.00 58.87  ? 48  LEU L CB  1 
ATOM 3283 C CG  . LEU D 4 47  ? 143.759 147.797 176.374 1.00 58.87  ? 48  LEU L CG  1 
ATOM 3284 C CD1 . LEU D 4 47  ? 144.645 148.991 176.634 1.00 58.87  ? 48  LEU L CD1 1 
ATOM 3285 C CD2 . LEU D 4 47  ? 142.300 148.187 176.464 1.00 58.87  ? 48  LEU L CD2 1 
ATOM 3286 N N   . ILE D 4 48  ? 145.178 145.224 172.996 1.00 58.93  ? 49  ILE L N   1 
ATOM 3287 C CA  . ILE D 4 48  ? 145.806 145.039 171.696 1.00 58.93  ? 49  ILE L CA  1 
ATOM 3288 C C   . ILE D 4 48  ? 146.433 143.654 171.628 1.00 58.93  ? 49  ILE L C   1 
ATOM 3289 O O   . ILE D 4 48  ? 147.172 143.257 172.535 1.00 58.93  ? 49  ILE L O   1 
ATOM 3290 C CB  . ILE D 4 48  ? 146.868 146.123 171.420 1.00 58.93  ? 49  ILE L CB  1 
ATOM 3291 C CG1 . ILE D 4 48  ? 146.220 147.510 171.330 1.00 58.93  ? 49  ILE L CG1 1 
ATOM 3292 C CG2 . ILE D 4 48  ? 147.653 145.804 170.157 1.00 58.93  ? 49  ILE L CG2 1 
ATOM 3293 C CD1 . ILE D 4 48  ? 145.262 147.668 170.177 1.00 58.93  ? 49  ILE L CD1 1 
ATOM 3294 N N   . TYR D 4 49  ? 146.153 142.935 170.543 1.00 63.93  ? 50  TYR L N   1 
ATOM 3295 C CA  . TYR D 4 49  ? 146.867 141.705 170.220 1.00 63.93  ? 50  TYR L CA  1 
ATOM 3296 C C   . TYR D 4 49  ? 147.380 141.801 168.793 1.00 63.93  ? 50  TYR L C   1 
ATOM 3297 O O   . TYR D 4 49  ? 146.970 142.671 168.022 1.00 63.93  ? 50  TYR L O   1 
ATOM 3298 C CB  . TYR D 4 49  ? 145.991 140.459 170.397 1.00 63.93  ? 50  TYR L CB  1 
ATOM 3299 C CG  . TYR D 4 49  ? 144.824 140.347 169.445 1.00 63.93  ? 50  TYR L CG  1 
ATOM 3300 C CD1 . TYR D 4 49  ? 144.966 139.732 168.212 1.00 63.93  ? 50  TYR L CD1 1 
ATOM 3301 C CD2 . TYR D 4 49  ? 143.572 140.827 169.794 1.00 63.93  ? 50  TYR L CD2 1 
ATOM 3302 C CE1 . TYR D 4 49  ? 143.900 139.614 167.347 1.00 63.93  ? 50  TYR L CE1 1 
ATOM 3303 C CE2 . TYR D 4 49  ? 142.497 140.712 168.935 1.00 63.93  ? 50  TYR L CE2 1 
ATOM 3304 C CZ  . TYR D 4 49  ? 142.666 140.104 167.714 1.00 63.93  ? 50  TYR L CZ  1 
ATOM 3305 O OH  . TYR D 4 49  ? 141.596 139.992 166.859 1.00 63.93  ? 50  TYR L OH  1 
ATOM 3306 N N   . SER D 4 50  ? 148.303 140.901 168.452 1.00 62.06  ? 51  SER L N   1 
ATOM 3307 C CA  . SER D 4 50  ? 149.041 140.940 167.190 1.00 62.06  ? 51  SER L CA  1 
ATOM 3308 C C   . SER D 4 50  ? 149.798 142.253 167.020 1.00 62.06  ? 51  SER L C   1 
ATOM 3309 O O   . SER D 4 50  ? 150.194 142.615 165.907 1.00 62.06  ? 51  SER L O   1 
ATOM 3310 C CB  . SER D 4 50  ? 148.116 140.690 165.994 1.00 62.06  ? 51  SER L CB  1 
ATOM 3311 O OG  . SER D 4 50  ? 147.376 139.498 166.166 1.00 62.06  ? 51  SER L OG  1 
ATOM 3312 N N   . ALA D 4 51  ? 149.991 142.964 168.131 1.00 66.43  ? 52  ALA L N   1 
ATOM 3313 C CA  . ALA D 4 51  ? 150.722 144.223 168.224 1.00 66.43  ? 52  ALA L CA  1 
ATOM 3314 C C   . ALA D 4 51  ? 150.127 145.347 167.383 1.00 66.43  ? 52  ALA L C   1 
ATOM 3315 O O   . ALA D 4 51  ? 150.658 146.458 167.383 1.00 66.43  ? 52  ALA L O   1 
ATOM 3316 C CB  . ALA D 4 51  ? 152.185 144.017 167.847 1.00 66.43  ? 52  ALA L CB  1 
ATOM 3317 N N   . SER D 4 52  ? 149.047 145.088 166.657 1.00 68.86  ? 53  SER L N   1 
ATOM 3318 C CA  . SER D 4 52  ? 148.408 146.142 165.883 1.00 68.86  ? 53  SER L CA  1 
ATOM 3319 C C   . SER D 4 52  ? 146.898 146.018 165.887 1.00 68.86  ? 53  SER L C   1 
ATOM 3320 O O   . SER D 4 52  ? 146.204 146.955 165.468 1.00 68.86  ? 53  SER L O   1 
ATOM 3321 C CB  . SER D 4 52  ? 148.940 146.134 164.440 1.00 68.86  ? 53  SER L CB  1 
ATOM 3322 O OG  . SER D 4 52  ? 148.671 144.903 163.795 1.00 68.86  ? 53  SER L OG  1 
ATOM 3323 N N   . SER D 4 53  ? 146.362 144.895 166.332 1.00 65.98  ? 54  SER L N   1 
ATOM 3324 C CA  . SER D 4 53  ? 144.947 144.606 166.192 1.00 65.98  ? 54  SER L CA  1 
ATOM 3325 C C   . SER D 4 53  ? 144.197 144.977 167.463 1.00 65.98  ? 54  SER L C   1 
ATOM 3326 O O   . SER D 4 53  ? 144.649 144.687 168.578 1.00 65.98  ? 54  SER L O   1 
ATOM 3327 C CB  . SER D 4 53  ? 144.710 143.134 165.852 1.00 65.98  ? 54  SER L CB  1 
ATOM 3328 O OG  . SER D 4 53  ? 143.355 142.916 165.503 1.00 65.98  ? 54  SER L OG  1 
ATOM 3329 N N   . LEU D 4 54  ? 143.051 145.629 167.282 1.00 69.12  ? 55  LEU L N   1 
ATOM 3330 C CA  . LEU D 4 54  ? 142.232 146.078 168.398 1.00 69.12  ? 55  LEU L CA  1 
ATOM 3331 C C   . LEU D 4 54  ? 141.322 144.942 168.850 1.00 69.12  ? 55  LEU L C   1 
ATOM 3332 O O   . LEU D 4 54  ? 140.543 144.407 168.054 1.00 69.12  ? 55  LEU L O   1 
ATOM 3333 C CB  . LEU D 4 54  ? 141.415 147.298 167.981 1.00 69.12  ? 55  LEU L CB  1 
ATOM 3334 C CG  . LEU D 4 54  ? 140.791 148.140 169.089 1.00 69.12  ? 55  LEU L CG  1 
ATOM 3335 C CD1 . LEU D 4 54  ? 141.875 148.769 169.942 1.00 69.12  ? 55  LEU L CD1 1 
ATOM 3336 C CD2 . LEU D 4 54  ? 139.890 149.199 168.487 1.00 69.12  ? 55  LEU L CD2 1 
ATOM 3337 N N   . TYR D 4 55  ? 141.420 144.575 170.128 1.00 69.97  ? 56  TYR L N   1 
ATOM 3338 C CA  . TYR D 4 55  ? 140.590 143.507 170.666 1.00 69.97  ? 56  TYR L CA  1 
ATOM 3339 C C   . TYR D 4 55  ? 139.124 143.907 170.632 1.00 69.97  ? 56  TYR L C   1 
ATOM 3340 O O   . TYR D 4 55  ? 138.778 145.072 170.838 1.00 69.97  ? 56  TYR L O   1 
ATOM 3341 C CB  . TYR D 4 55  ? 141.011 143.172 172.096 1.00 69.97  ? 56  TYR L CB  1 
ATOM 3342 C CG  . TYR D 4 55  ? 140.208 142.052 172.715 1.00 69.97  ? 56  TYR L CG  1 
ATOM 3343 C CD1 . TYR D 4 55  ? 140.146 140.805 172.111 1.00 69.97  ? 56  TYR L CD1 1 
ATOM 3344 C CD2 . TYR D 4 55  ? 139.519 142.237 173.906 1.00 69.97  ? 56  TYR L CD2 1 
ATOM 3345 C CE1 . TYR D 4 55  ? 139.416 139.778 172.668 1.00 69.97  ? 56  TYR L CE1 1 
ATOM 3346 C CE2 . TYR D 4 55  ? 138.787 141.214 174.471 1.00 69.97  ? 56  TYR L CE2 1 
ATOM 3347 C CZ  . TYR D 4 55  ? 138.739 139.987 173.846 1.00 69.97  ? 56  TYR L CZ  1 
ATOM 3348 O OH  . TYR D 4 55  ? 138.013 138.961 174.400 1.00 69.97  ? 56  TYR L OH  1 
ATOM 3349 N N   . SER D 4 56  ? 138.263 142.934 170.352 1.00 78.83  ? 57  SER L N   1 
ATOM 3350 C CA  . SER D 4 56  ? 136.831 143.194 170.269 1.00 78.83  ? 57  SER L CA  1 
ATOM 3351 C C   . SER D 4 56  ? 136.308 143.750 171.587 1.00 78.83  ? 57  SER L C   1 
ATOM 3352 O O   . SER D 4 56  ? 136.635 143.244 172.666 1.00 78.83  ? 57  SER L O   1 
ATOM 3353 C CB  . SER D 4 56  ? 136.083 141.916 169.895 1.00 78.83  ? 57  SER L CB  1 
ATOM 3354 O OG  . SER D 4 56  ? 134.698 142.166 169.738 1.00 78.83  ? 57  SER L OG  1 
ATOM 3355 N N   . GLY D 4 57  ? 135.497 144.801 171.494 1.00 81.01  ? 58  GLY L N   1 
ATOM 3356 C CA  . GLY D 4 57  ? 134.958 145.468 172.657 1.00 81.01  ? 58  GLY L CA  1 
ATOM 3357 C C   . GLY D 4 57  ? 135.787 146.619 173.183 1.00 81.01  ? 58  GLY L C   1 
ATOM 3358 O O   . GLY D 4 57  ? 135.319 147.341 174.071 1.00 81.01  ? 58  GLY L O   1 
ATOM 3359 N N   . VAL D 4 58  ? 136.997 146.816 172.671 1.00 78.09  ? 59  VAL L N   1 
ATOM 3360 C CA  . VAL D 4 58  ? 137.865 147.898 173.123 1.00 78.09  ? 59  VAL L CA  1 
ATOM 3361 C C   . VAL D 4 58  ? 137.474 149.163 172.368 1.00 78.09  ? 59  VAL L C   1 
ATOM 3362 O O   . VAL D 4 58  ? 137.211 149.100 171.159 1.00 78.09  ? 59  VAL L O   1 
ATOM 3363 C CB  . VAL D 4 58  ? 139.346 147.549 172.921 1.00 78.09  ? 59  VAL L CB  1 
ATOM 3364 C CG1 . VAL D 4 58  ? 140.240 148.684 173.380 1.00 78.09  ? 59  VAL L CG1 1 
ATOM 3365 C CG2 . VAL D 4 58  ? 139.690 146.285 173.673 1.00 78.09  ? 59  VAL L CG2 1 
ATOM 3366 N N   . PRO D 4 59  ? 137.386 150.314 173.035 1.00 80.64  ? 60  PRO L N   1 
ATOM 3367 C CA  . PRO D 4 59  ? 137.084 151.558 172.319 1.00 80.64  ? 60  PRO L CA  1 
ATOM 3368 C C   . PRO D 4 59  ? 138.091 151.834 171.209 1.00 80.64  ? 60  PRO L C   1 
ATOM 3369 O O   . PRO D 4 59  ? 139.293 151.605 171.360 1.00 80.64  ? 60  PRO L O   1 
ATOM 3370 C CB  . PRO D 4 59  ? 137.158 152.620 173.420 1.00 80.64  ? 60  PRO L CB  1 
ATOM 3371 C CG  . PRO D 4 59  ? 136.811 151.884 174.658 1.00 80.64  ? 60  PRO L CG  1 
ATOM 3372 C CD  . PRO D 4 59  ? 137.378 150.504 174.496 1.00 80.64  ? 60  PRO L CD  1 
ATOM 3373 N N   . SER D 4 60  ? 137.584 152.352 170.087 1.00 83.88  ? 61  SER L N   1 
ATOM 3374 C CA  . SER D 4 60  ? 138.396 152.510 168.887 1.00 83.88  ? 61  SER L CA  1 
ATOM 3375 C C   . SER D 4 60  ? 139.539 153.500 169.065 1.00 83.88  ? 61  SER L C   1 
ATOM 3376 O O   . SER D 4 60  ? 140.453 153.520 168.231 1.00 83.88  ? 61  SER L O   1 
ATOM 3377 C CB  . SER D 4 60  ? 137.515 152.939 167.710 1.00 83.88  ? 61  SER L CB  1 
ATOM 3378 O OG  . SER D 4 60  ? 136.752 154.090 168.026 1.00 83.88  ? 61  SER L OG  1 
ATOM 3379 N N   . ARG D 4 61  ? 139.521 154.317 170.117 1.00 79.97  ? 62  ARG L N   1 
ATOM 3380 C CA  . ARG D 4 61  ? 140.567 155.317 170.295 1.00 79.97  ? 62  ARG L CA  1 
ATOM 3381 C C   . ARG D 4 61  ? 141.928 154.702 170.600 1.00 79.97  ? 62  ARG L C   1 
ATOM 3382 O O   . ARG D 4 61  ? 142.939 155.408 170.532 1.00 79.97  ? 62  ARG L O   1 
ATOM 3383 C CB  . ARG D 4 61  ? 140.165 156.301 171.397 1.00 79.97  ? 62  ARG L CB  1 
ATOM 3384 C CG  . ARG D 4 61  ? 139.736 155.648 172.696 1.00 79.97  ? 62  ARG L CG  1 
ATOM 3385 C CD  . ARG D 4 61  ? 139.239 156.679 173.692 1.00 79.97  ? 62  ARG L CD  1 
ATOM 3386 N NE  . ARG D 4 61  ? 138.987 156.092 175.002 1.00 79.97  ? 62  ARG L NE  1 
ATOM 3387 C CZ  . ARG D 4 61  ? 137.818 155.611 175.394 1.00 79.97  ? 62  ARG L CZ  1 
ATOM 3388 N NH1 . ARG D 4 61  ? 136.759 155.638 174.602 1.00 79.97  ? 62  ARG L NH1 1 
ATOM 3389 N NH2 . ARG D 4 61  ? 137.704 155.098 176.615 1.00 79.97  ? 62  ARG L NH2 1 
ATOM 3390 N N   . PHE D 4 62  ? 141.982 153.420 170.942 1.00 69.75  ? 63  PHE L N   1 
ATOM 3391 C CA  . PHE D 4 62  ? 143.246 152.733 171.165 1.00 69.75  ? 63  PHE L CA  1 
ATOM 3392 C C   . PHE D 4 62  ? 143.791 152.212 169.844 1.00 69.75  ? 63  PHE L C   1 
ATOM 3393 O O   . PHE D 4 62  ? 143.037 151.728 168.996 1.00 69.75  ? 63  PHE L O   1 
ATOM 3394 C CB  . PHE D 4 62  ? 143.069 151.575 172.147 1.00 69.75  ? 63  PHE L CB  1 
ATOM 3395 C CG  . PHE D 4 62  ? 142.659 152.005 173.520 1.00 69.75  ? 63  PHE L CG  1 
ATOM 3396 C CD1 . PHE D 4 62  ? 143.612 152.322 174.468 1.00 69.75  ? 63  PHE L CD1 1 
ATOM 3397 C CD2 . PHE D 4 62  ? 141.323 152.093 173.863 1.00 69.75  ? 63  PHE L CD2 1 
ATOM 3398 C CE1 . PHE D 4 62  ? 143.242 152.718 175.726 1.00 69.75  ? 63  PHE L CE1 1 
ATOM 3399 C CE2 . PHE D 4 62  ? 140.947 152.486 175.121 1.00 69.75  ? 63  PHE L CE2 1 
ATOM 3400 C CZ  . PHE D 4 62  ? 141.907 152.800 176.055 1.00 69.75  ? 63  PHE L CZ  1 
ATOM 3401 N N   . SER D 4 63  ? 145.104 152.310 169.673 1.00 75.99  ? 64  SER L N   1 
ATOM 3402 C CA  . SER D 4 63  ? 145.716 151.850 168.433 1.00 75.99  ? 64  SER L CA  1 
ATOM 3403 C C   . SER D 4 63  ? 147.134 151.383 168.708 1.00 75.99  ? 64  SER L C   1 
ATOM 3404 O O   . SER D 4 63  ? 147.899 152.070 169.384 1.00 75.99  ? 64  SER L O   1 
ATOM 3405 C CB  . SER D 4 63  ? 145.719 152.952 167.368 1.00 75.99  ? 64  SER L CB  1 
ATOM 3406 O OG  . SER D 4 63  ? 146.281 152.479 166.156 1.00 75.99  ? 64  SER L OG  1 
ATOM 3407 N N   . GLY D 4 64  ? 147.477 150.215 168.168 1.00 73.66  ? 65  GLY L N   1 
ATOM 3408 C CA  . GLY D 4 64  ? 148.806 149.668 168.297 1.00 73.66  ? 65  GLY L CA  1 
ATOM 3409 C C   . GLY D 4 64  ? 149.607 149.797 167.012 1.00 73.66  ? 65  GLY L C   1 
ATOM 3410 O O   . GLY D 4 64  ? 149.084 150.069 165.935 1.00 73.66  ? 65  GLY L O   1 
ATOM 3411 N N   . SER D 4 65  ? 150.909 149.581 167.154 1.00 76.02  ? 66  SER L N   1 
ATOM 3412 C CA  . SER D 4 65  ? 151.832 149.781 166.049 1.00 76.02  ? 66  SER L CA  1 
ATOM 3413 C C   . SER D 4 65  ? 153.102 148.988 166.305 1.00 76.02  ? 66  SER L C   1 
ATOM 3414 O O   . SER D 4 65  ? 153.558 148.884 167.446 1.00 76.02  ? 66  SER L O   1 
ATOM 3415 C CB  . SER D 4 65  ? 152.164 151.265 165.864 1.00 76.02  ? 66  SER L CB  1 
ATOM 3416 O OG  . SER D 4 65  ? 153.240 151.436 164.962 1.00 76.02  ? 66  SER L OG  1 
ATOM 3417 N N   . ARG D 4 66  ? 153.675 148.456 165.230 1.00 74.92  ? 67  ARG L N   1 
ATOM 3418 C CA  . ARG D 4 66  ? 154.868 147.631 165.299 1.00 74.92  ? 67  ARG L CA  1 
ATOM 3419 C C   . ARG D 4 66  ? 155.913 148.165 164.334 1.00 74.92  ? 67  ARG L C   1 
ATOM 3420 O O   . ARG D 4 66  ? 155.608 148.420 163.165 1.00 74.92  ? 67  ARG L O   1 
ATOM 3421 C CB  . ARG D 4 66  ? 154.549 146.170 164.969 1.00 74.92  ? 67  ARG L CB  1 
ATOM 3422 C CG  . ARG D 4 66  ? 155.790 145.308 164.784 1.00 74.92  ? 67  ARG L CG  1 
ATOM 3423 C CD  . ARG D 4 66  ? 155.444 143.859 164.495 1.00 74.92  ? 67  ARG L CD  1 
ATOM 3424 N NE  . ARG D 4 66  ? 156.637 143.021 164.492 1.00 74.92  ? 67  ARG L NE  1 
ATOM 3425 C CZ  . ARG D 4 66  ? 157.254 142.601 163.398 1.00 74.92  ? 67  ARG L CZ  1 
ATOM 3426 N NH1 . ARG D 4 66  ? 156.793 142.889 162.192 1.00 74.92  ? 67  ARG L NH1 1 
ATOM 3427 N NH2 . ARG D 4 66  ? 158.363 141.878 163.514 1.00 74.92  ? 67  ARG L NH2 1 
ATOM 3428 N N   . SER D 4 67  ? 157.141 148.325 164.819 1.00 80.82  ? 68  SER L N   1 
ATOM 3429 C CA  . SER D 4 67  ? 158.284 148.675 163.983 1.00 80.82  ? 68  SER L CA  1 
ATOM 3430 C C   . SER D 4 67  ? 159.462 147.837 164.469 1.00 80.82  ? 68  SER L C   1 
ATOM 3431 O O   . SER D 4 67  ? 160.164 148.229 165.409 1.00 80.82  ? 68  SER L O   1 
ATOM 3432 C CB  . SER D 4 67  ? 158.599 150.162 164.050 1.00 80.82  ? 68  SER L CB  1 
ATOM 3433 O OG  . SER D 4 67  ? 159.841 150.439 163.427 1.00 80.82  ? 68  SER L OG  1 
ATOM 3434 N N   . GLY D 4 68  ? 159.680 146.699 163.824 1.00 78.91  ? 69  GLY L N   1 
ATOM 3435 C CA  . GLY D 4 68  ? 160.701 145.781 164.296 1.00 78.91  ? 69  GLY L CA  1 
ATOM 3436 C C   . GLY D 4 68  ? 160.385 145.305 165.701 1.00 78.91  ? 69  GLY L C   1 
ATOM 3437 O O   . GLY D 4 68  ? 159.309 144.761 165.975 1.00 78.91  ? 69  GLY L O   1 
ATOM 3438 N N   . THR D 4 69  ? 161.333 145.522 166.608 1.00 79.69  ? 70  THR L N   1 
ATOM 3439 C CA  . THR D 4 69  ? 161.210 145.121 168.001 1.00 79.69  ? 70  THR L CA  1 
ATOM 3440 C C   . THR D 4 69  ? 160.592 146.198 168.885 1.00 79.69  ? 70  THR L C   1 
ATOM 3441 O O   . THR D 4 69  ? 160.492 145.994 170.099 1.00 79.69  ? 70  THR L O   1 
ATOM 3442 C CB  . THR D 4 69  ? 162.583 144.740 168.557 1.00 79.69  ? 70  THR L CB  1 
ATOM 3443 O OG1 . THR D 4 69  ? 163.424 145.897 168.578 1.00 79.69  ? 70  THR L OG1 1 
ATOM 3444 C CG2 . THR D 4 69  ? 163.225 143.680 167.688 1.00 79.69  ? 70  THR L CG2 1 
ATOM 3445 N N   . ASP D 4 70  ? 160.187 147.335 168.314 1.00 80.05  ? 71  ASP L N   1 
ATOM 3446 C CA  . ASP D 4 70  ? 159.552 148.405 169.074 1.00 80.05  ? 71  ASP L CA  1 
ATOM 3447 C C   . ASP D 4 70  ? 158.057 148.399 168.786 1.00 80.05  ? 71  ASP L C   1 
ATOM 3448 O O   . ASP D 4 70  ? 157.644 148.352 167.626 1.00 80.05  ? 71  ASP L O   1 
ATOM 3449 C CB  . ASP D 4 70  ? 160.162 149.761 168.715 1.00 80.05  ? 71  ASP L CB  1 
ATOM 3450 C CG  . ASP D 4 70  ? 161.633 149.851 169.071 1.00 80.05  ? 71  ASP L CG  1 
ATOM 3451 O OD1 . ASP D 4 70  ? 162.219 148.824 169.473 1.00 80.05  ? 71  ASP L OD1 1 
ATOM 3452 O OD2 . ASP D 4 70  ? 162.206 150.953 168.957 1.00 80.05  ? 71  ASP L OD2 1 
ATOM 3453 N N   . PHE D 4 71  ? 157.249 148.435 169.843 1.00 71.75  ? 72  PHE L N   1 
ATOM 3454 C CA  . PHE D 4 71  ? 155.798 148.416 169.744 1.00 71.75  ? 72  PHE L CA  1 
ATOM 3455 C C   . PHE D 4 71  ? 155.240 149.626 170.481 1.00 71.75  ? 72  PHE L C   1 
ATOM 3456 O O   . PHE D 4 71  ? 155.824 150.096 171.458 1.00 71.75  ? 72  PHE L O   1 
ATOM 3457 C CB  . PHE D 4 71  ? 155.237 147.109 170.320 1.00 71.75  ? 72  PHE L CB  1 
ATOM 3458 C CG  . PHE D 4 71  ? 155.843 145.878 169.703 1.00 71.75  ? 72  PHE L CG  1 
ATOM 3459 C CD1 . PHE D 4 71  ? 157.064 145.393 170.139 1.00 71.75  ? 72  PHE L CD1 1 
ATOM 3460 C CD2 . PHE D 4 71  ? 155.202 145.223 168.671 1.00 71.75  ? 72  PHE L CD2 1 
ATOM 3461 C CE1 . PHE D 4 71  ? 157.625 144.280 169.562 1.00 71.75  ? 72  PHE L CE1 1 
ATOM 3462 C CE2 . PHE D 4 71  ? 155.755 144.107 168.098 1.00 71.75  ? 72  PHE L CE2 1 
ATOM 3463 C CZ  . PHE D 4 71  ? 156.967 143.636 168.539 1.00 71.75  ? 72  PHE L CZ  1 
ATOM 3464 N N   . THR D 4 72  ? 154.115 150.143 169.991 1.00 70.59  ? 73  THR L N   1 
ATOM 3465 C CA  . THR D 4 72  ? 153.560 151.398 170.478 1.00 70.59  ? 73  THR L CA  1 
ATOM 3466 C C   . THR D 4 72  ? 152.061 151.262 170.692 1.00 70.59  ? 73  THR L C   1 
ATOM 3467 O O   . THR D 4 72  ? 151.355 150.688 169.857 1.00 70.59  ? 73  THR L O   1 
ATOM 3468 C CB  . THR D 4 72  ? 153.852 152.544 169.491 1.00 70.59  ? 73  THR L CB  1 
ATOM 3469 O OG1 . THR D 4 72  ? 155.264 152.776 169.435 1.00 70.59  ? 73  THR L OG1 1 
ATOM 3470 C CG2 . THR D 4 72  ? 153.158 153.822 169.912 1.00 70.59  ? 73  THR L CG2 1 
ATOM 3471 N N   . LEU D 4 73  ? 151.587 151.781 171.821 1.00 66.67  ? 74  LEU L N   1 
ATOM 3472 C CA  . LEU D 4 73  ? 150.169 151.895 172.121 1.00 66.67  ? 74  LEU L CA  1 
ATOM 3473 C C   . LEU D 4 73  ? 149.808 153.371 172.173 1.00 66.67  ? 74  LEU L C   1 
ATOM 3474 O O   . LEU D 4 73  ? 150.491 154.153 172.837 1.00 66.67  ? 74  LEU L O   1 
ATOM 3475 C CB  . LEU D 4 73  ? 149.831 151.221 173.451 1.00 66.67  ? 74  LEU L CB  1 
ATOM 3476 C CG  . LEU D 4 73  ? 148.400 151.428 173.941 1.00 66.67  ? 74  LEU L CG  1 
ATOM 3477 C CD1 . LEU D 4 73  ? 147.421 150.619 173.117 1.00 66.67  ? 74  LEU L CD1 1 
ATOM 3478 C CD2 . LEU D 4 73  ? 148.278 151.092 175.412 1.00 66.67  ? 74  LEU L CD2 1 
ATOM 3479 N N   . THR D 4 74  ? 148.752 153.760 171.472 1.00 76.47  ? 75  THR L N   1 
ATOM 3480 C CA  . THR D 4 74  ? 148.327 155.146 171.448 1.00 76.47  ? 75  THR L CA  1 
ATOM 3481 C C   . THR D 4 74  ? 146.854 155.244 171.807 1.00 76.47  ? 75  THR L C   1 
ATOM 3482 O O   . THR D 4 74  ? 146.067 154.333 171.541 1.00 76.47  ? 75  THR L O   1 
ATOM 3483 C CB  . THR D 4 74  ? 148.570 155.806 170.072 1.00 76.47  ? 75  THR L CB  1 
ATOM 3484 O OG1 . THR D 4 74  ? 147.854 155.099 169.055 1.00 76.47  ? 75  THR L OG1 1 
ATOM 3485 C CG2 . THR D 4 74  ? 150.048 155.810 169.733 1.00 76.47  ? 75  THR L CG2 1 
ATOM 3486 N N   . ILE D 4 75  ? 146.499 156.359 172.437 1.00 80.29  ? 76  ILE L N   1 
ATOM 3487 C CA  . ILE D 4 75  ? 145.112 156.728 172.683 1.00 80.29  ? 76  ILE L CA  1 
ATOM 3488 C C   . ILE D 4 75  ? 144.883 158.063 171.991 1.00 80.29  ? 76  ILE L C   1 
ATOM 3489 O O   . ILE D 4 75  ? 145.571 159.051 172.294 1.00 80.29  ? 76  ILE L O   1 
ATOM 3490 C CB  . ILE D 4 75  ? 144.789 156.801 174.184 1.00 80.29  ? 76  ILE L CB  1 
ATOM 3491 C CG1 . ILE D 4 75  ? 145.377 155.584 174.900 1.00 80.29  ? 76  ILE L CG1 1 
ATOM 3492 C CG2 . ILE D 4 75  ? 143.285 156.843 174.397 1.00 80.29  ? 76  ILE L CG2 1 
ATOM 3493 C CD1 . ILE D 4 75  ? 145.190 155.589 176.399 1.00 80.29  ? 76  ILE L CD1 1 
ATOM 3494 N N   . SER D 4 76  ? 143.942 158.076 171.041 1.00 89.30  ? 77  SER L N   1 
ATOM 3495 C CA  . SER D 4 76  ? 143.718 159.250 170.201 1.00 89.30  ? 77  SER L CA  1 
ATOM 3496 C C   . SER D 4 76  ? 143.263 160.441 171.027 1.00 89.30  ? 77  SER L C   1 
ATOM 3497 O O   . SER D 4 76  ? 143.705 161.573 170.797 1.00 89.30  ? 77  SER L O   1 
ATOM 3498 C CB  . SER D 4 76  ? 142.682 158.932 169.122 1.00 89.30  ? 77  SER L CB  1 
ATOM 3499 O OG  . SER D 4 76  ? 143.105 157.856 168.304 1.00 89.30  ? 77  SER L OG  1 
ATOM 3500 N N   . SER D 4 77  ? 142.377 160.210 171.987 1.00 91.34  ? 78  SER L N   1 
ATOM 3501 C CA  . SER D 4 77  ? 141.846 161.285 172.813 1.00 91.34  ? 78  SER L CA  1 
ATOM 3502 C C   . SER D 4 77  ? 141.529 160.684 174.172 1.00 91.34  ? 78  SER L C   1 
ATOM 3503 O O   . SER D 4 77  ? 140.586 159.896 174.294 1.00 91.34  ? 78  SER L O   1 
ATOM 3504 C CB  . SER D 4 77  ? 140.609 161.901 172.174 1.00 91.34  ? 78  SER L CB  1 
ATOM 3505 O OG  . SER D 4 77  ? 140.272 163.130 172.791 1.00 91.34  ? 78  SER L OG  1 
ATOM 3506 N N   . LEU D 4 78  ? 142.317 161.054 175.177 1.00 86.24  ? 79  LEU L N   1 
ATOM 3507 C CA  . LEU D 4 78  ? 142.227 160.428 176.490 1.00 86.24  ? 79  LEU L CA  1 
ATOM 3508 C C   . LEU D 4 78  ? 140.865 160.669 177.120 1.00 86.24  ? 79  LEU L C   1 
ATOM 3509 O O   . LEU D 4 78  ? 140.363 161.795 177.135 1.00 86.24  ? 79  LEU L O   1 
ATOM 3510 C CB  . LEU D 4 78  ? 143.326 160.978 177.393 1.00 86.24  ? 79  LEU L CB  1 
ATOM 3511 C CG  . LEU D 4 78  ? 143.774 160.136 178.580 1.00 86.24  ? 79  LEU L CG  1 
ATOM 3512 C CD1 . LEU D 4 78  ? 144.253 158.786 178.099 1.00 86.24  ? 79  LEU L CD1 1 
ATOM 3513 C CD2 . LEU D 4 78  ? 144.885 160.855 179.312 1.00 86.24  ? 79  LEU L CD2 1 
ATOM 3514 N N   . GLN D 4 79  ? 140.271 159.621 177.633 1.00 87.02  ? 80  GLN L N   1 
ATOM 3515 C CA  . GLN D 4 79  ? 139.064 159.752 178.425 1.00 87.02  ? 80  GLN L CA  1 
ATOM 3516 C C   . GLN D 4 79  ? 139.395 159.600 179.900 1.00 87.02  ? 80  GLN L C   1 
ATOM 3517 O O   . GLN D 4 79  ? 140.436 159.042 180.258 1.00 87.02  ? 80  GLN L O   1 
ATOM 3518 C CB  . GLN D 4 79  ? 138.030 158.701 178.007 1.00 87.02  ? 80  GLN L CB  1 
ATOM 3519 C CG  . GLN D 4 79  ? 137.587 158.812 176.562 1.00 87.02  ? 80  GLN L CG  1 
ATOM 3520 C CD  . GLN D 4 79  ? 137.080 160.191 176.220 1.00 87.02  ? 80  GLN L CD  1 
ATOM 3521 O OE1 . GLN D 4 79  ? 135.938 160.535 176.519 1.00 87.02  ? 80  GLN L OE1 1 
ATOM 3522 N NE2 . GLN D 4 79  ? 137.932 160.999 175.594 1.00 87.02  ? 80  GLN L NE2 1 
ATOM 3523 N N   . PRO D 4 80  ? 138.542 160.100 180.796 1.00 86.88  ? 81  PRO L N   1 
ATOM 3524 C CA  . PRO D 4 80  ? 138.774 159.851 182.226 1.00 86.88  ? 81  PRO L CA  1 
ATOM 3525 C C   . PRO D 4 80  ? 138.789 158.375 182.574 1.00 86.88  ? 81  PRO L C   1 
ATOM 3526 O O   . PRO D 4 80  ? 139.407 157.993 183.574 1.00 86.88  ? 81  PRO L O   1 
ATOM 3527 C CB  . PRO D 4 80  ? 137.608 160.580 182.908 1.00 86.88  ? 81  PRO L CB  1 
ATOM 3528 C CG  . PRO D 4 80  ? 136.574 160.743 181.835 1.00 86.88  ? 81  PRO L CG  1 
ATOM 3529 C CD  . PRO D 4 80  ? 137.355 160.943 180.576 1.00 86.88  ? 81  PRO L CD  1 
ATOM 3530 N N   . GLU D 4 81  ? 138.132 157.533 181.774 1.00 86.81  ? 82  GLU L N   1 
ATOM 3531 C CA  . GLU D 4 81  ? 138.155 156.094 181.997 1.00 86.81  ? 82  GLU L CA  1 
ATOM 3532 C C   . GLU D 4 81  ? 139.516 155.479 181.707 1.00 86.81  ? 82  GLU L C   1 
ATOM 3533 O O   . GLU D 4 81  ? 139.770 154.347 182.124 1.00 86.81  ? 82  GLU L O   1 
ATOM 3534 C CB  . GLU D 4 81  ? 137.096 155.421 181.126 1.00 86.81  ? 82  GLU L CB  1 
ATOM 3535 C CG  . GLU D 4 81  ? 135.727 156.057 181.231 1.00 86.81  ? 82  GLU L CG  1 
ATOM 3536 C CD  . GLU D 4 81  ? 134.770 155.572 180.164 1.00 86.81  ? 82  GLU L CD  1 
ATOM 3537 O OE1 . GLU D 4 81  ? 135.194 154.798 179.281 1.00 86.81  ? 82  GLU L OE1 1 
ATOM 3538 O OE2 . GLU D 4 81  ? 133.588 155.967 180.207 1.00 86.81  ? 82  GLU L OE2 1 
ATOM 3539 N N   . ASP D 4 82  ? 140.385 156.189 180.995 1.00 80.71  ? 83  ASP L N   1 
ATOM 3540 C CA  . ASP D 4 82  ? 141.653 155.642 180.538 1.00 80.71  ? 83  ASP L CA  1 
ATOM 3541 C C   . ASP D 4 82  ? 142.810 155.932 181.483 1.00 80.71  ? 83  ASP L C   1 
ATOM 3542 O O   . ASP D 4 82  ? 143.960 155.665 181.127 1.00 80.71  ? 83  ASP L O   1 
ATOM 3543 C CB  . ASP D 4 82  ? 141.986 156.184 179.147 1.00 80.71  ? 83  ASP L CB  1 
ATOM 3544 C CG  . ASP D 4 82  ? 140.899 155.903 178.139 1.00 80.71  ? 83  ASP L CG  1 
ATOM 3545 O OD1 . ASP D 4 82  ? 140.106 154.966 178.360 1.00 80.71  ? 83  ASP L OD1 1 
ATOM 3546 O OD2 . ASP D 4 82  ? 140.839 156.617 177.120 1.00 80.71  ? 83  ASP L OD2 1 
ATOM 3547 N N   . PHE D 4 83  ? 142.547 156.496 182.654 1.00 76.84  ? 84  PHE L N   1 
ATOM 3548 C CA  . PHE D 4 83  ? 143.606 156.734 183.632 1.00 76.84  ? 84  PHE L CA  1 
ATOM 3549 C C   . PHE D 4 83  ? 143.798 155.453 184.432 1.00 76.84  ? 84  PHE L C   1 
ATOM 3550 O O   . PHE D 4 83  ? 143.217 155.260 185.500 1.00 76.84  ? 84  PHE L O   1 
ATOM 3551 C CB  . PHE D 4 83  ? 143.266 157.922 184.518 1.00 76.84  ? 84  PHE L CB  1 
ATOM 3552 C CG  . PHE D 4 83  ? 143.251 159.225 183.785 1.00 76.84  ? 84  PHE L CG  1 
ATOM 3553 C CD1 . PHE D 4 83  ? 144.434 159.885 183.505 1.00 76.84  ? 84  PHE L CD1 1 
ATOM 3554 C CD2 . PHE D 4 83  ? 142.059 159.784 183.367 1.00 76.84  ? 84  PHE L CD2 1 
ATOM 3555 C CE1 . PHE D 4 83  ? 144.430 161.076 182.826 1.00 76.84  ? 84  PHE L CE1 1 
ATOM 3556 C CE2 . PHE D 4 83  ? 142.047 160.979 182.687 1.00 76.84  ? 84  PHE L CE2 1 
ATOM 3557 C CZ  . PHE D 4 83  ? 143.234 161.625 182.416 1.00 76.84  ? 84  PHE L CZ  1 
ATOM 3558 N N   . ALA D 4 84  ? 144.625 154.559 183.893 1.00 68.06  ? 85  ALA L N   1 
ATOM 3559 C CA  . ALA D 4 84  ? 144.842 153.244 184.474 1.00 68.06  ? 85  ALA L CA  1 
ATOM 3560 C C   . ALA D 4 84  ? 146.274 152.813 184.194 1.00 68.06  ? 85  ALA L C   1 
ATOM 3561 O O   . ALA D 4 84  ? 147.083 153.574 183.659 1.00 68.06  ? 85  ALA L O   1 
ATOM 3562 C CB  . ALA D 4 84  ? 143.843 152.223 183.923 1.00 68.06  ? 85  ALA L CB  1 
ATOM 3563 N N   . THR D 4 85  ? 146.587 151.579 184.580 1.00 62.24  ? 86  THR L N   1 
ATOM 3564 C CA  . THR D 4 85  ? 147.892 150.996 184.304 1.00 62.24  ? 86  THR L CA  1 
ATOM 3565 C C   . THR D 4 85  ? 147.835 150.193 183.009 1.00 62.24  ? 86  THR L C   1 
ATOM 3566 O O   . THR D 4 85  ? 146.826 149.562 182.700 1.00 62.24  ? 86  THR L O   1 
ATOM 3567 C CB  . THR D 4 85  ? 148.341 150.103 185.461 1.00 62.24  ? 86  THR L CB  1 
ATOM 3568 O OG1 . THR D 4 85  ? 147.965 150.707 186.703 1.00 62.24  ? 86  THR L OG1 1 
ATOM 3569 C CG2 . THR D 4 85  ? 149.850 149.934 185.440 1.00 62.24  ? 86  THR L CG2 1 
ATOM 3570 N N   . TYR D 4 86  ? 148.913 150.241 182.240 1.00 61.27  ? 87  TYR L N   1 
ATOM 3571 C CA  . TYR D 4 86  ? 149.008 149.550 180.965 1.00 61.27  ? 87  TYR L CA  1 
ATOM 3572 C C   . TYR D 4 86  ? 150.265 148.694 180.929 1.00 61.27  ? 87  TYR L C   1 
ATOM 3573 O O   . TYR D 4 86  ? 151.326 149.111 181.402 1.00 61.27  ? 87  TYR L O   1 
ATOM 3574 C CB  . TYR D 4 86  ? 148.995 150.548 179.798 1.00 61.27  ? 87  TYR L CB  1 
ATOM 3575 C CG  . TYR D 4 86  ? 147.704 151.328 179.706 1.00 61.27  ? 87  TYR L CG  1 
ATOM 3576 C CD1 . TYR D 4 86  ? 146.601 150.802 179.057 1.00 61.27  ? 87  TYR L CD1 1 
ATOM 3577 C CD2 . TYR D 4 86  ? 147.584 152.583 180.287 1.00 61.27  ? 87  TYR L CD2 1 
ATOM 3578 C CE1 . TYR D 4 86  ? 145.416 151.504 178.977 1.00 61.27  ? 87  TYR L CE1 1 
ATOM 3579 C CE2 . TYR D 4 86  ? 146.401 153.291 180.214 1.00 61.27  ? 87  TYR L CE2 1 
ATOM 3580 C CZ  . TYR D 4 86  ? 145.321 152.744 179.558 1.00 61.27  ? 87  TYR L CZ  1 
ATOM 3581 O OH  . TYR D 4 86  ? 144.138 153.435 179.472 1.00 61.27  ? 87  TYR L OH  1 
ATOM 3582 N N   . TYR D 4 87  ? 150.137 147.491 180.368 1.00 61.21  ? 88  TYR L N   1 
ATOM 3583 C CA  . TYR D 4 87  ? 151.238 146.537 180.298 1.00 61.21  ? 88  TYR L CA  1 
ATOM 3584 C C   . TYR D 4 87  ? 151.395 146.017 178.876 1.00 61.21  ? 88  TYR L C   1 
ATOM 3585 O O   . TYR D 4 87  ? 150.413 145.854 178.147 1.00 61.21  ? 88  TYR L O   1 
ATOM 3586 C CB  . TYR D 4 87  ? 151.021 145.343 181.246 1.00 61.21  ? 88  TYR L CB  1 
ATOM 3587 C CG  . TYR D 4 87  ? 150.801 145.708 182.697 1.00 61.21  ? 88  TYR L CG  1 
ATOM 3588 C CD1 . TYR D 4 87  ? 151.873 145.914 183.551 1.00 61.21  ? 88  TYR L CD1 1 
ATOM 3589 C CD2 . TYR D 4 87  ? 149.521 145.832 183.216 1.00 61.21  ? 88  TYR L CD2 1 
ATOM 3590 C CE1 . TYR D 4 87  ? 151.676 146.241 184.875 1.00 61.21  ? 88  TYR L CE1 1 
ATOM 3591 C CE2 . TYR D 4 87  ? 149.316 146.158 184.535 1.00 61.21  ? 88  TYR L CE2 1 
ATOM 3592 C CZ  . TYR D 4 87  ? 150.394 146.359 185.360 1.00 61.21  ? 88  TYR L CZ  1 
ATOM 3593 O OH  . TYR D 4 87  ? 150.183 146.686 186.678 1.00 61.21  ? 88  TYR L OH  1 
ATOM 3594 N N   . CYS D 4 88  ? 152.641 145.749 178.494 1.00 64.61  ? 89  CYS L N   1 
ATOM 3595 C CA  . CYS D 4 88  ? 152.961 145.045 177.261 1.00 64.61  ? 89  CYS L CA  1 
ATOM 3596 C C   . CYS D 4 88  ? 153.528 143.672 177.593 1.00 64.61  ? 89  CYS L C   1 
ATOM 3597 O O   . CYS D 4 88  ? 154.169 143.481 178.630 1.00 64.61  ? 89  CYS L O   1 
ATOM 3598 C CB  . CYS D 4 88  ? 153.971 145.817 176.410 1.00 64.61  ? 89  CYS L CB  1 
ATOM 3599 S SG  . CYS D 4 88  ? 155.535 146.135 177.244 1.00 64.61  ? 89  CYS L SG  1 
ATOM 3600 N N   . GLN D 4 89  ? 153.286 142.714 176.708 1.00 58.38  ? 90  GLN L N   1 
ATOM 3601 C CA  . GLN D 4 89  ? 153.778 141.365 176.923 1.00 58.38  ? 90  GLN L CA  1 
ATOM 3602 C C   . GLN D 4 89  ? 154.225 140.761 175.605 1.00 58.38  ? 90  GLN L C   1 
ATOM 3603 O O   . GLN D 4 89  ? 153.689 141.081 174.540 1.00 58.38  ? 90  GLN L O   1 
ATOM 3604 C CB  . GLN D 4 89  ? 152.719 140.455 177.568 1.00 58.38  ? 90  GLN L CB  1 
ATOM 3605 C CG  . GLN D 4 89  ? 151.677 139.930 176.595 1.00 58.38  ? 90  GLN L CG  1 
ATOM 3606 C CD  . GLN D 4 89  ? 150.899 138.755 177.146 1.00 58.38  ? 90  GLN L CD  1 
ATOM 3607 O OE1 . GLN D 4 89  ? 150.799 138.582 178.353 1.00 58.38  ? 90  GLN L OE1 1 
ATOM 3608 N NE2 . GLN D 4 89  ? 150.348 137.938 176.259 1.00 58.38  ? 90  GLN L NE2 1 
ATOM 3609 N N   . GLN D 4 90  ? 155.220 139.884 175.703 1.00 61.60  ? 91  GLN L N   1 
ATOM 3610 C CA  . GLN D 4 90  ? 155.644 139.027 174.604 1.00 61.60  ? 91  GLN L CA  1 
ATOM 3611 C C   . GLN D 4 90  ? 155.013 137.654 174.787 1.00 61.60  ? 91  GLN L C   1 
ATOM 3612 O O   . GLN D 4 90  ? 155.218 137.012 175.838 1.00 61.60  ? 91  GLN L O   1 
ATOM 3613 C CB  . GLN D 4 90  ? 157.161 138.897 174.581 1.00 61.60  ? 91  GLN L CB  1 
ATOM 3614 C CG  . GLN D 4 90  ? 157.673 138.024 173.463 1.00 61.60  ? 91  GLN L CG  1 
ATOM 3615 C CD  . GLN D 4 90  ? 157.741 138.771 172.151 1.00 61.60  ? 91  GLN L CD  1 
ATOM 3616 O OE1 . GLN D 4 90  ? 158.266 139.881 172.093 1.00 61.60  ? 91  GLN L OE1 1 
ATOM 3617 N NE2 . GLN D 4 90  ? 157.199 138.176 171.092 1.00 61.60  ? 91  GLN L NE2 1 
ATOM 3618 N N   . TYR D 4 91  ? 154.274 137.197 173.777 1.00 59.15  ? 92  TYR L N   1 
ATOM 3619 C CA  . TYR D 4 91  ? 153.636 135.892 173.885 1.00 59.15  ? 92  TYR L CA  1 
ATOM 3620 C C   . TYR D 4 91  ? 154.065 134.983 172.736 1.00 59.15  ? 92  TYR L C   1 
ATOM 3621 O O   . TYR D 4 91  ? 153.235 134.351 172.080 1.00 59.15  ? 92  TYR L O   1 
ATOM 3622 C CB  . TYR D 4 91  ? 152.110 136.027 173.959 1.00 59.15  ? 92  TYR L CB  1 
ATOM 3623 C CG  . TYR D 4 91  ? 151.402 136.623 172.765 1.00 59.15  ? 92  TYR L CG  1 
ATOM 3624 C CD1 . TYR D 4 91  ? 151.391 137.991 172.556 1.00 59.15  ? 92  TYR L CD1 1 
ATOM 3625 C CD2 . TYR D 4 91  ? 150.698 135.822 171.873 1.00 59.15  ? 92  TYR L CD2 1 
ATOM 3626 C CE1 . TYR D 4 91  ? 150.721 138.544 171.478 1.00 59.15  ? 92  TYR L CE1 1 
ATOM 3627 C CE2 . TYR D 4 91  ? 150.023 136.366 170.792 1.00 59.15  ? 92  TYR L CE2 1 
ATOM 3628 C CZ  . TYR D 4 91  ? 150.041 137.728 170.600 1.00 59.15  ? 92  TYR L CZ  1 
ATOM 3629 O OH  . TYR D 4 91  ? 149.378 138.276 169.530 1.00 59.15  ? 92  TYR L OH  1 
ATOM 3630 N N   . LEU D 4 92  ? 155.374 134.894 172.511 1.00 57.53  ? 93  LEU L N   1 
ATOM 3631 C CA  . LEU D 4 92  ? 155.881 134.065 171.422 1.00 57.53  ? 93  LEU L CA  1 
ATOM 3632 C C   . LEU D 4 92  ? 155.544 132.593 171.624 1.00 57.53  ? 93  LEU L C   1 
ATOM 3633 O O   . LEU D 4 92  ? 155.222 131.891 170.662 1.00 57.53  ? 93  LEU L O   1 
ATOM 3634 C CB  . LEU D 4 92  ? 157.385 134.254 171.276 1.00 57.53  ? 93  LEU L CB  1 
ATOM 3635 C CG  . LEU D 4 92  ? 158.011 133.636 170.027 1.00 57.53  ? 93  LEU L CG  1 
ATOM 3636 C CD1 . LEU D 4 92  ? 157.134 133.881 168.818 1.00 57.53  ? 93  LEU L CD1 1 
ATOM 3637 C CD2 . LEU D 4 92  ? 159.390 134.212 169.791 1.00 57.53  ? 93  LEU L CD2 1 
ATOM 3638 N N   . TYR D 4 93  ? 155.621 132.104 172.863 1.00 56.38  ? 94  TYR L N   1 
ATOM 3639 C CA  . TYR D 4 93  ? 155.270 130.720 173.165 1.00 56.38  ? 94  TYR L CA  1 
ATOM 3640 C C   . TYR D 4 93  ? 154.860 130.628 174.626 1.00 56.38  ? 94  TYR L C   1 
ATOM 3641 O O   . TYR D 4 93  ? 155.207 131.486 175.438 1.00 56.38  ? 94  TYR L O   1 
ATOM 3642 C CB  . TYR D 4 93  ? 156.425 129.762 172.856 1.00 56.38  ? 94  TYR L CB  1 
ATOM 3643 C CG  . TYR D 4 93  ? 156.058 128.298 172.977 1.00 56.38  ? 94  TYR L CG  1 
ATOM 3644 C CD1 . TYR D 4 93  ? 154.925 127.792 172.353 1.00 56.38  ? 94  TYR L CD1 1 
ATOM 3645 C CD2 . TYR D 4 93  ? 156.849 127.422 173.709 1.00 56.38  ? 94  TYR L CD2 1 
ATOM 3646 C CE1 . TYR D 4 93  ? 154.588 126.461 172.463 1.00 56.38  ? 94  TYR L CE1 1 
ATOM 3647 C CE2 . TYR D 4 93  ? 156.520 126.090 173.821 1.00 56.38  ? 94  TYR L CE2 1 
ATOM 3648 C CZ  . TYR D 4 93  ? 155.388 125.616 173.197 1.00 56.38  ? 94  TYR L CZ  1 
ATOM 3649 O OH  . TYR D 4 93  ? 155.055 124.290 173.304 1.00 56.38  ? 94  TYR L OH  1 
ATOM 3650 N N   . TYR D 4 94  ? 154.108 129.564 174.941 1.00 59.41  ? 95  TYR L N   1 
ATOM 3651 C CA  . TYR D 4 94  ? 153.498 129.412 176.261 1.00 59.41  ? 95  TYR L CA  1 
ATOM 3652 C C   . TYR D 4 94  ? 154.521 129.526 177.383 1.00 59.41  ? 95  TYR L C   1 
ATOM 3653 O O   . TYR D 4 94  ? 154.239 130.114 178.432 1.00 59.41  ? 95  TYR L O   1 
ATOM 3654 C CB  . TYR D 4 94  ? 152.777 128.070 176.353 1.00 59.41  ? 95  TYR L CB  1 
ATOM 3655 C CG  . TYR D 4 94  ? 151.714 127.851 175.306 1.00 59.41  ? 95  TYR L CG  1 
ATOM 3656 C CD1 . TYR D 4 94  ? 150.675 128.744 175.147 1.00 59.41  ? 95  TYR L CD1 1 
ATOM 3657 C CD2 . TYR D 4 94  ? 151.738 126.730 174.497 1.00 59.41  ? 95  TYR L CD2 1 
ATOM 3658 C CE1 . TYR D 4 94  ? 149.702 128.539 174.199 1.00 59.41  ? 95  TYR L CE1 1 
ATOM 3659 C CE2 . TYR D 4 94  ? 150.769 126.516 173.549 1.00 59.41  ? 95  TYR L CE2 1 
ATOM 3660 C CZ  . TYR D 4 94  ? 149.755 127.421 173.405 1.00 59.41  ? 95  TYR L CZ  1 
ATOM 3661 O OH  . TYR D 4 94  ? 148.795 127.199 172.453 1.00 59.41  ? 95  TYR L OH  1 
ATOM 3662 N N   . SER D 4 95  ? 155.709 128.969 177.187 1.00 61.02  ? 96  SER L N   1 
ATOM 3663 C CA  . SER D 4 95  ? 156.744 128.983 178.208 1.00 61.02  ? 96  SER L CA  1 
ATOM 3664 C C   . SER D 4 95  ? 157.586 130.249 178.188 1.00 61.02  ? 96  SER L C   1 
ATOM 3665 O O   . SER D 4 95  ? 158.453 130.410 179.051 1.00 61.02  ? 96  SER L O   1 
ATOM 3666 C CB  . SER D 4 95  ? 157.659 127.767 178.047 1.00 61.02  ? 96  SER L CB  1 
ATOM 3667 O OG  . SER D 4 95  ? 156.910 126.565 178.017 1.00 61.02  ? 96  SER L OG  1 
ATOM 3668 N N   . LEU D 4 96  ? 157.364 131.145 177.229 1.00 59.94  ? 97  LEU L N   1 
ATOM 3669 C CA  . LEU D 4 96  ? 158.189 132.332 177.061 1.00 59.94  ? 97  LEU L CA  1 
ATOM 3670 C C   . LEU D 4 96  ? 157.476 133.622 177.451 1.00 59.94  ? 97  LEU L C   1 
ATOM 3671 O O   . LEU D 4 96  ? 157.988 134.706 177.161 1.00 59.94  ? 97  LEU L O   1 
ATOM 3672 C CB  . LEU D 4 96  ? 158.675 132.429 175.612 1.00 59.94  ? 97  LEU L CB  1 
ATOM 3673 C CG  . LEU D 4 96  ? 159.333 131.183 175.017 1.00 59.94  ? 97  LEU L CG  1 
ATOM 3674 C CD1 . LEU D 4 96  ? 159.618 131.406 173.551 1.00 59.94  ? 97  LEU L CD1 1 
ATOM 3675 C CD2 . LEU D 4 96  ? 160.609 130.836 175.762 1.00 59.94  ? 97  LEU L CD2 1 
ATOM 3676 N N   . VAL D 4 97  ? 156.308 133.535 178.093 1.00 64.27  ? 98  VAL L N   1 
ATOM 3677 C CA  . VAL D 4 97  ? 155.529 134.731 178.385 1.00 64.27  ? 98  VAL L CA  1 
ATOM 3678 C C   . VAL D 4 97  ? 156.294 135.625 179.342 1.00 64.27  ? 98  VAL L C   1 
ATOM 3679 O O   . VAL D 4 97  ? 156.781 135.178 180.390 1.00 64.27  ? 98  VAL L O   1 
ATOM 3680 C CB  . VAL D 4 97  ? 154.154 134.353 178.951 1.00 64.27  ? 98  VAL L CB  1 
ATOM 3681 C CG1 . VAL D 4 97  ? 153.429 135.588 179.442 1.00 64.27  ? 98  VAL L CG1 1 
ATOM 3682 C CG2 . VAL D 4 97  ? 153.334 133.661 177.900 1.00 64.27  ? 98  VAL L CG2 1 
ATOM 3683 N N   . THR D 4 98  ? 156.420 136.901 178.959 1.00 64.21  ? 99  THR L N   1 
ATOM 3684 C CA  . THR D 4 98  ? 157.077 137.896 179.807 1.00 64.21  ? 99  THR L CA  1 
ATOM 3685 C C   . THR D 4 98  ? 156.340 139.217 179.657 1.00 64.21  ? 99  THR L C   1 
ATOM 3686 O O   . THR D 4 98  ? 155.900 139.566 178.558 1.00 64.21  ? 99  THR L O   1 
ATOM 3687 C CB  . THR D 4 98  ? 158.554 138.067 179.433 1.00 64.21  ? 99  THR L CB  1 
ATOM 3688 O OG1 . THR D 4 98  ? 159.211 136.796 179.492 1.00 64.21  ? 99  THR L OG1 1 
ATOM 3689 C CG2 . THR D 4 98  ? 159.252 139.024 180.384 1.00 64.21  ? 99  THR L CG2 1 
ATOM 3690 N N   . PHE D 4 99  ? 156.191 139.941 180.763 1.00 64.22  ? 100 PHE L N   1 
ATOM 3691 C CA  . PHE D 4 99  ? 155.528 141.235 180.778 1.00 64.22  ? 100 PHE L CA  1 
ATOM 3692 C C   . PHE D 4 99  ? 156.540 142.360 180.962 1.00 64.22  ? 100 PHE L C   1 
ATOM 3693 O O   . PHE D 4 99  ? 157.675 142.146 181.394 1.00 64.22  ? 100 PHE L O   1 
ATOM 3694 C CB  . PHE D 4 99  ? 154.485 141.308 181.896 1.00 64.22  ? 100 PHE L CB  1 
ATOM 3695 C CG  . PHE D 4 99  ? 153.357 140.338 181.743 1.00 64.22  ? 100 PHE L CG  1 
ATOM 3696 C CD1 . PHE D 4 99  ? 153.487 139.035 182.185 1.00 64.22  ? 100 PHE L CD1 1 
ATOM 3697 C CD2 . PHE D 4 99  ? 152.156 140.737 181.189 1.00 64.22  ? 100 PHE L CD2 1 
ATOM 3698 C CE1 . PHE D 4 99  ? 152.449 138.145 182.058 1.00 64.22  ? 100 PHE L CE1 1 
ATOM 3699 C CE2 . PHE D 4 99  ? 151.111 139.852 181.064 1.00 64.22  ? 100 PHE L CE2 1 
ATOM 3700 C CZ  . PHE D 4 99  ? 151.257 138.554 181.498 1.00 64.22  ? 100 PHE L CZ  1 
ATOM 3701 N N   . GLY D 4 100 ? 156.110 143.571 180.623 1.00 67.61  ? 101 GLY L N   1 
ATOM 3702 C CA  . GLY D 4 100 ? 156.873 144.762 180.919 1.00 67.61  ? 101 GLY L CA  1 
ATOM 3703 C C   . GLY D 4 100 ? 156.647 145.222 182.347 1.00 67.61  ? 101 GLY L C   1 
ATOM 3704 O O   . GLY D 4 100 ? 155.965 144.581 183.147 1.00 67.61  ? 101 GLY L O   1 
ATOM 3705 N N   . GLN D 4 101 ? 157.232 146.377 182.663 1.00 75.75  ? 102 GLN L N   1 
ATOM 3706 C CA  . GLN D 4 101 ? 157.146 146.907 184.018 1.00 75.75  ? 102 GLN L CA  1 
ATOM 3707 C C   . GLN D 4 101 ? 155.849 147.655 184.281 1.00 75.75  ? 102 GLN L C   1 
ATOM 3708 O O   . GLN D 4 101 ? 155.511 147.886 185.445 1.00 75.75  ? 102 GLN L O   1 
ATOM 3709 C CB  . GLN D 4 101 ? 158.329 147.833 184.308 1.00 75.75  ? 102 GLN L CB  1 
ATOM 3710 C CG  . GLN D 4 101 ? 159.686 147.161 184.215 1.00 75.75  ? 102 GLN L CG  1 
ATOM 3711 C CD  . GLN D 4 101 ? 160.149 146.981 182.784 1.00 75.75  ? 102 GLN L CD  1 
ATOM 3712 O OE1 . GLN D 4 101 ? 160.408 147.954 182.078 1.00 75.75  ? 102 GLN L OE1 1 
ATOM 3713 N NE2 . GLN D 4 101 ? 160.243 145.731 182.344 1.00 75.75  ? 102 GLN L NE2 1 
ATOM 3714 N N   . GLY D 4 102 ? 155.124 148.032 183.245 1.00 70.64  ? 103 GLY L N   1 
ATOM 3715 C CA  . GLY D 4 102 ? 153.874 148.737 183.460 1.00 70.64  ? 103 GLY L CA  1 
ATOM 3716 C C   . GLY D 4 102 ? 154.043 150.241 183.412 1.00 70.64  ? 103 GLY L C   1 
ATOM 3717 O O   . GLY D 4 102 ? 155.062 150.803 183.813 1.00 70.64  ? 103 GLY L O   1 
ATOM 3718 N N   . THR D 4 103 ? 153.016 150.906 182.890 1.00 66.96  ? 104 THR L N   1 
ATOM 3719 C CA  . THR D 4 103 ? 152.950 152.357 182.842 1.00 66.96  ? 104 THR L CA  1 
ATOM 3720 C C   . THR D 4 103 ? 151.608 152.804 183.387 1.00 66.96  ? 104 THR L C   1 
ATOM 3721 O O   . THR D 4 103 ? 150.598 152.138 183.192 1.00 66.96  ? 104 THR L O   1 
ATOM 3722 C CB  . THR D 4 103 ? 153.119 152.890 181.417 1.00 66.96  ? 104 THR L CB  1 
ATOM 3723 O OG1 . THR D 4 103 ? 151.948 152.585 180.651 1.00 66.96  ? 104 THR L OG1 1 
ATOM 3724 C CG2 . THR D 4 103 ? 154.332 152.255 180.757 1.00 66.96  ? 104 THR L CG2 1 
ATOM 3725 N N   . LYS D 4 104 ? 151.588 153.945 184.063 1.00 73.35  ? 105 LYS L N   1 
ATOM 3726 C CA  . LYS D 4 104 ? 150.358 154.452 184.652 1.00 73.35  ? 105 LYS L CA  1 
ATOM 3727 C C   . LYS D 4 104 ? 150.049 155.829 184.091 1.00 73.35  ? 105 LYS L C   1 
ATOM 3728 O O   . LYS D 4 104 ? 150.906 156.718 184.104 1.00 73.35  ? 105 LYS L O   1 
ATOM 3729 C CB  . LYS D 4 104 ? 150.447 154.509 186.176 1.00 73.35  ? 105 LYS L CB  1 
ATOM 3730 C CG  . LYS D 4 104 ? 149.103 154.764 186.833 1.00 73.35  ? 105 LYS L CG  1 
ATOM 3731 C CD  . LYS D 4 104 ? 149.193 154.725 188.342 1.00 73.35  ? 105 LYS L CD  1 
ATOM 3732 C CE  . LYS D 4 104 ? 147.812 154.841 188.957 1.00 73.35  ? 105 LYS L CE  1 
ATOM 3733 N NZ  . LYS D 4 104 ? 147.868 154.757 190.439 1.00 73.35  ? 105 LYS L NZ  1 
ATOM 3734 N N   . VAL D 4 105 ? 148.827 156.000 183.605 1.00 71.41  ? 106 VAL L N   1 
ATOM 3735 C CA  . VAL D 4 105 ? 148.359 157.275 183.086 1.00 71.41  ? 106 VAL L CA  1 
ATOM 3736 C C   . VAL D 4 105 ? 147.602 157.994 184.193 1.00 71.41  ? 106 VAL L C   1 
ATOM 3737 O O   . VAL D 4 105 ? 146.596 157.486 184.703 1.00 71.41  ? 106 VAL L O   1 
ATOM 3738 C CB  . VAL D 4 105 ? 147.477 157.086 181.847 1.00 71.41  ? 106 VAL L CB  1 
ATOM 3739 C CG1 . VAL D 4 105 ? 147.053 158.434 181.294 1.00 71.41  ? 106 VAL L CG1 1 
ATOM 3740 C CG2 . VAL D 4 105 ? 148.217 156.281 180.794 1.00 71.41  ? 106 VAL L CG2 1 
ATOM 3741 N N   . GLU D 4 106 ? 148.069 159.183 184.548 1.00 82.49  ? 107 GLU L N   1 
ATOM 3742 C CA  . GLU D 4 106 ? 147.493 159.962 185.627 1.00 82.49  ? 107 GLU L CA  1 
ATOM 3743 C C   . GLU D 4 106 ? 147.060 161.318 185.092 1.00 82.49  ? 107 GLU L C   1 
ATOM 3744 O O   . GLU D 4 106 ? 147.504 161.758 184.028 1.00 82.49  ? 107 GLU L O   1 
ATOM 3745 C CB  . GLU D 4 106 ? 148.488 160.126 186.784 1.00 82.49  ? 107 GLU L CB  1 
ATOM 3746 C CG  . GLU D 4 106 ? 148.725 158.837 187.556 1.00 82.49  ? 107 GLU L CG  1 
ATOM 3747 C CD  . GLU D 4 106 ? 149.828 158.962 188.581 1.00 82.49  ? 107 GLU L CD  1 
ATOM 3748 O OE1 . GLU D 4 106 ? 150.798 159.705 188.320 1.00 82.49  ? 107 GLU L OE1 1 
ATOM 3749 O OE2 . GLU D 4 106 ? 149.720 158.319 189.647 1.00 82.49  ? 107 GLU L OE2 1 
ATOM 3750 N N   . ILE D 4 107 ? 146.170 161.967 185.834 1.00 79.44  ? 108 ILE L N   1 
ATOM 3751 C CA  . ILE D 4 107 ? 145.552 163.205 185.373 1.00 79.44  ? 108 ILE L CA  1 
ATOM 3752 C C   . ILE D 4 107 ? 146.547 164.349 185.499 1.00 79.44  ? 108 ILE L C   1 
ATOM 3753 O O   . ILE D 4 107 ? 147.128 164.575 186.567 1.00 79.44  ? 108 ILE L O   1 
ATOM 3754 C CB  . ILE D 4 107 ? 144.263 163.495 186.154 1.00 79.44  ? 108 ILE L CB  1 
ATOM 3755 C CG1 . ILE D 4 107 ? 143.202 162.443 185.830 1.00 79.44  ? 108 ILE L CG1 1 
ATOM 3756 C CG2 . ILE D 4 107 ? 143.752 164.879 185.825 1.00 79.44  ? 108 ILE L CG2 1 
ATOM 3757 C CD1 . ILE D 4 107 ? 141.834 162.755 186.387 1.00 79.44  ? 108 ILE L CD1 1 
ATOM 3758 N N   . LYS D 4 108 ? 146.754 165.065 184.395 1.00 80.71  ? 109 LYS L N   1 
ATOM 3759 C CA  . LYS D 4 108 ? 147.584 166.259 184.390 1.00 80.71  ? 109 LYS L CA  1 
ATOM 3760 C C   . LYS D 4 108 ? 146.811 167.413 185.011 1.00 80.71  ? 109 LYS L C   1 
ATOM 3761 O O   . LYS D 4 108 ? 145.667 167.681 184.633 1.00 80.71  ? 109 LYS L O   1 
ATOM 3762 C CB  . LYS D 4 108 ? 148.002 166.599 182.962 1.00 80.71  ? 109 LYS L CB  1 
ATOM 3763 C CG  . LYS D 4 108 ? 148.930 167.782 182.817 1.00 80.71  ? 109 LYS L CG  1 
ATOM 3764 C CD  . LYS D 4 108 ? 149.384 167.879 181.374 1.00 80.71  ? 109 LYS L CD  1 
ATOM 3765 C CE  . LYS D 4 108 ? 150.340 169.025 181.149 1.00 80.71  ? 109 LYS L CE  1 
ATOM 3766 N NZ  . LYS D 4 108 ? 150.857 169.020 179.752 1.00 80.71  ? 109 LYS L NZ  1 
ATOM 3767 N N   . ARG D 4 109 ? 147.432 168.083 185.980 1.00 73.83  ? 110 ARG L N   1 
ATOM 3768 C CA  . ARG D 4 109 ? 146.798 169.179 186.695 1.00 73.83  ? 110 ARG L CA  1 
ATOM 3769 C C   . ARG D 4 109 ? 147.804 170.299 186.893 1.00 73.83  ? 110 ARG L C   1 
ATOM 3770 O O   . ARG D 4 109 ? 148.980 170.184 186.535 1.00 73.83  ? 110 ARG L O   1 
ATOM 3771 C CB  . ARG D 4 109 ? 146.249 168.716 188.045 1.00 73.83  ? 110 ARG L CB  1 
ATOM 3772 C CG  . ARG D 4 109 ? 145.145 167.685 187.954 1.00 73.83  ? 110 ARG L CG  1 
ATOM 3773 C CD  . ARG D 4 109 ? 143.883 168.297 187.384 1.00 73.83  ? 110 ARG L CD  1 
ATOM 3774 N NE  . ARG D 4 109 ? 143.380 169.356 188.250 1.00 73.83  ? 110 ARG L NE  1 
ATOM 3775 C CZ  . ARG D 4 109 ? 142.281 170.059 188.018 1.00 73.83  ? 110 ARG L CZ  1 
ATOM 3776 N NH1 . ARG D 4 109 ? 141.536 169.845 186.946 1.00 73.83  ? 110 ARG L NH1 1 
ATOM 3777 N NH2 . ARG D 4 109 ? 141.920 171.002 188.884 1.00 73.83  ? 110 ARG L NH2 1 
ATOM 3778 N N   . THR D 4 110 ? 147.330 171.395 187.479 1.00 74.81  ? 111 THR L N   1 
ATOM 3779 C CA  . THR D 4 110 ? 148.216 172.458 187.920 1.00 74.81  ? 111 THR L CA  1 
ATOM 3780 C C   . THR D 4 110 ? 149.120 171.957 189.034 1.00 74.81  ? 111 THR L C   1 
ATOM 3781 O O   . THR D 4 110 ? 149.034 170.799 189.454 1.00 74.81  ? 111 THR L O   1 
ATOM 3782 C CB  . THR D 4 110 ? 147.416 173.671 188.394 1.00 74.81  ? 111 THR L CB  1 
ATOM 3783 O OG1 . THR D 4 110 ? 146.444 173.254 189.360 1.00 74.81  ? 111 THR L OG1 1 
ATOM 3784 C CG2 . THR D 4 110 ? 146.712 174.332 187.226 1.00 74.81  ? 111 THR L CG2 1 
ATOM 3785 N N   . VAL D 4 111 ? 150.011 172.810 189.509 1.00 70.49  ? 112 VAL L N   1 
ATOM 3786 C CA  . VAL D 4 111 ? 150.892 172.485 190.619 1.00 70.49  ? 112 VAL L CA  1 
ATOM 3787 C C   . VAL D 4 111 ? 150.426 173.254 191.848 1.00 70.49  ? 112 VAL L C   1 
ATOM 3788 O O   . VAL D 4 111 ? 150.226 174.473 191.787 1.00 70.49  ? 112 VAL L O   1 
ATOM 3789 C CB  . VAL D 4 111 ? 152.357 172.799 190.283 1.00 70.49  ? 112 VAL L CB  1 
ATOM 3790 C CG1 . VAL D 4 111 ? 153.238 172.591 191.495 1.00 70.49  ? 112 VAL L CG1 1 
ATOM 3791 C CG2 . VAL D 4 111 ? 152.821 171.924 189.146 1.00 70.49  ? 112 VAL L CG2 1 
ATOM 3792 N N   . ALA D 4 112 ? 150.236 172.543 192.957 1.00 72.41  ? 113 ALA L N   1 
ATOM 3793 C CA  . ALA D 4 112 ? 149.888 173.176 194.221 1.00 72.41  ? 113 ALA L CA  1 
ATOM 3794 C C   . ALA D 4 112 ? 150.589 172.442 195.347 1.00 72.41  ? 113 ALA L C   1 
ATOM 3795 O O   . ALA D 4 112 ? 150.436 171.227 195.487 1.00 72.41  ? 113 ALA L O   1 
ATOM 3796 C CB  . ALA D 4 112 ? 148.375 173.185 194.459 1.00 72.41  ? 113 ALA L CB  1 
ATOM 3797 N N   . ALA D 4 113 ? 151.335 173.187 196.149 1.00 75.66  ? 114 ALA L N   1 
ATOM 3798 C CA  . ALA D 4 113 ? 152.102 172.598 197.231 1.00 75.66  ? 114 ALA L CA  1 
ATOM 3799 C C   . ALA D 4 113 ? 151.174 172.035 198.305 1.00 75.66  ? 114 ALA L C   1 
ATOM 3800 O O   . ALA D 4 113 ? 150.128 172.624 198.600 1.00 75.66  ? 114 ALA L O   1 
ATOM 3801 C CB  . ALA D 4 113 ? 153.034 173.638 197.842 1.00 75.66  ? 114 ALA L CB  1 
ATOM 3802 N N   . PRO D 4 114 ? 151.532 170.912 198.912 1.00 78.40  ? 115 PRO L N   1 
ATOM 3803 C CA  . PRO D 4 114 ? 150.670 170.318 199.930 1.00 78.40  ? 115 PRO L CA  1 
ATOM 3804 C C   . PRO D 4 114 ? 150.837 170.990 201.282 1.00 78.40  ? 115 PRO L C   1 
ATOM 3805 O O   . PRO D 4 114 ? 151.893 171.533 201.618 1.00 78.40  ? 115 PRO L O   1 
ATOM 3806 C CB  . PRO D 4 114 ? 151.155 168.866 199.979 1.00 78.40  ? 115 PRO L CB  1 
ATOM 3807 C CG  . PRO D 4 114 ? 152.615 168.984 199.694 1.00 78.40  ? 115 PRO L CG  1 
ATOM 3808 C CD  . PRO D 4 114 ? 152.771 170.136 198.723 1.00 78.40  ? 115 PRO L CD  1 
ATOM 3809 N N   . SER D 4 115 ? 149.765 170.939 202.062 1.00 91.42  ? 116 SER L N   1 
ATOM 3810 C CA  . SER D 4 115 ? 149.826 171.375 203.449 1.00 91.42  ? 116 SER L CA  1 
ATOM 3811 C C   . SER D 4 115 ? 150.599 170.350 204.263 1.00 91.42  ? 116 SER L C   1 
ATOM 3812 O O   . SER D 4 115 ? 150.432 169.143 204.086 1.00 91.42  ? 116 SER L O   1 
ATOM 3813 C CB  . SER D 4 115 ? 148.418 171.545 204.016 1.00 91.42  ? 116 SER L CB  1 
ATOM 3814 O OG  . SER D 4 115 ? 147.527 172.080 203.051 1.00 91.42  ? 116 SER L OG  1 
ATOM 3815 N N   . VAL D 4 116 ? 151.441 170.830 205.168 1.00 96.32  ? 117 VAL L N   1 
ATOM 3816 C CA  . VAL D 4 116 ? 152.399 169.987 205.867 1.00 96.32  ? 117 VAL L CA  1 
ATOM 3817 C C   . VAL D 4 116 ? 152.089 170.016 207.356 1.00 96.32  ? 117 VAL L C   1 
ATOM 3818 O O   . VAL D 4 116 ? 151.956 171.092 207.950 1.00 96.32  ? 117 VAL L O   1 
ATOM 3819 C CB  . VAL D 4 116 ? 153.842 170.440 205.590 1.00 96.32  ? 117 VAL L CB  1 
ATOM 3820 C CG1 . VAL D 4 116 ? 154.828 169.457 206.178 1.00 96.32  ? 117 VAL L CG1 1 
ATOM 3821 C CG2 . VAL D 4 116 ? 154.057 170.583 204.098 1.00 96.32  ? 117 VAL L CG2 1 
ATOM 3822 N N   . PHE D 4 117 ? 151.972 168.833 207.952 1.00 103.85 ? 118 PHE L N   1 
ATOM 3823 C CA  . PHE D 4 117 ? 151.675 168.684 209.368 1.00 103.85 ? 118 PHE L CA  1 
ATOM 3824 C C   . PHE D 4 117 ? 152.630 167.675 209.986 1.00 103.85 ? 118 PHE L C   1 
ATOM 3825 O O   . PHE D 4 117 ? 153.091 166.747 209.316 1.00 103.85 ? 118 PHE L O   1 
ATOM 3826 C CB  . PHE D 4 117 ? 150.237 168.215 209.597 1.00 103.85 ? 118 PHE L CB  1 
ATOM 3827 C CG  . PHE D 4 117 ? 149.206 169.026 208.870 1.00 103.85 ? 118 PHE L CG  1 
ATOM 3828 C CD1 . PHE D 4 117 ? 148.895 168.757 207.550 1.00 103.85 ? 118 PHE L CD1 1 
ATOM 3829 C CD2 . PHE D 4 117 ? 148.531 170.045 209.516 1.00 103.85 ? 118 PHE L CD2 1 
ATOM 3830 C CE1 . PHE D 4 117 ? 147.941 169.501 206.886 1.00 103.85 ? 118 PHE L CE1 1 
ATOM 3831 C CE2 . PHE D 4 117 ? 147.577 170.791 208.855 1.00 103.85 ? 118 PHE L CE2 1 
ATOM 3832 C CZ  . PHE D 4 117 ? 147.279 170.518 207.539 1.00 103.85 ? 118 PHE L CZ  1 
ATOM 3833 N N   . ILE D 4 118 ? 152.908 167.850 211.275 1.00 114.49 ? 119 ILE L N   1 
ATOM 3834 C CA  . ILE D 4 118 ? 153.708 166.908 212.046 1.00 114.49 ? 119 ILE L CA  1 
ATOM 3835 C C   . ILE D 4 118 ? 152.936 166.566 213.310 1.00 114.49 ? 119 ILE L C   1 
ATOM 3836 O O   . ILE D 4 118 ? 152.327 167.441 213.936 1.00 114.49 ? 119 ILE L O   1 
ATOM 3837 C CB  . ILE D 4 118 ? 155.116 167.459 212.374 1.00 114.49 ? 119 ILE L CB  1 
ATOM 3838 C CG1 . ILE D 4 118 ? 155.939 166.413 213.133 1.00 114.49 ? 119 ILE L CG1 1 
ATOM 3839 C CG2 . ILE D 4 118 ? 155.032 168.751 213.168 1.00 114.49 ? 119 ILE L CG2 1 
ATOM 3840 C CD1 . ILE D 4 118 ? 157.426 166.700 213.183 1.00 114.49 ? 119 ILE L CD1 1 
ATOM 3841 N N   . PHE D 4 119 ? 152.923 165.285 213.661 1.00 120.18 ? 120 PHE L N   1 
ATOM 3842 C CA  . PHE D 4 119 ? 152.197 164.815 214.822 1.00 120.18 ? 120 PHE L CA  1 
ATOM 3843 C C   . PHE D 4 119 ? 153.116 164.006 215.726 1.00 120.18 ? 120 PHE L C   1 
ATOM 3844 O O   . PHE D 4 119 ? 153.777 163.056 215.255 1.00 120.18 ? 120 PHE L O   1 
ATOM 3845 C CB  . PHE D 4 119 ? 150.997 163.956 214.436 1.00 120.18 ? 120 PHE L CB  1 
ATOM 3846 C CG  . PHE D 4 119 ? 149.993 164.650 213.575 1.00 120.18 ? 120 PHE L CG  1 
ATOM 3847 C CD1 . PHE D 4 119 ? 149.064 165.508 214.126 1.00 120.18 ? 120 PHE L CD1 1 
ATOM 3848 C CD2 . PHE D 4 119 ? 149.962 164.425 212.213 1.00 120.18 ? 120 PHE L CD2 1 
ATOM 3849 C CE1 . PHE D 4 119 ? 148.130 166.138 213.336 1.00 120.18 ? 120 PHE L CE1 1 
ATOM 3850 C CE2 . PHE D 4 119 ? 149.031 165.050 211.418 1.00 120.18 ? 120 PHE L CE2 1 
ATOM 3851 C CZ  . PHE D 4 119 ? 148.115 165.910 211.981 1.00 120.18 ? 120 PHE L CZ  1 
ATOM 3852 N N   . PRO D 4 120 ? 153.152 164.319 217.013 1.00 129.90 ? 121 PRO L N   1 
ATOM 3853 C CA  . PRO D 4 120 ? 153.891 163.507 217.973 1.00 129.90 ? 121 PRO L CA  1 
ATOM 3854 C C   . PRO D 4 120 ? 153.119 162.252 218.334 1.00 129.90 ? 121 PRO L C   1 
ATOM 3855 O O   . PRO D 4 120 ? 151.903 162.173 218.103 1.00 129.90 ? 121 PRO L O   1 
ATOM 3856 C CB  . PRO D 4 120 ? 154.022 164.445 219.182 1.00 129.90 ? 121 PRO L CB  1 
ATOM 3857 C CG  . PRO D 4 120 ? 152.829 165.317 219.094 1.00 129.90 ? 121 PRO L CG  1 
ATOM 3858 C CD  . PRO D 4 120 ? 152.588 165.532 217.628 1.00 129.90 ? 121 PRO L CD  1 
ATOM 3859 N N   . PRO D 4 121 ? 153.783 161.246 218.900 1.00 134.79 ? 122 PRO L N   1 
ATOM 3860 C CA  . PRO D 4 121 ? 153.054 160.060 219.356 1.00 134.79 ? 122 PRO L CA  1 
ATOM 3861 C C   . PRO D 4 121 ? 152.160 160.388 220.540 1.00 134.79 ? 122 PRO L C   1 
ATOM 3862 O O   . PRO D 4 121 ? 152.457 161.272 221.346 1.00 134.79 ? 122 PRO L O   1 
ATOM 3863 C CB  . PRO D 4 121 ? 154.171 159.093 219.755 1.00 134.79 ? 122 PRO L CB  1 
ATOM 3864 C CG  . PRO D 4 121 ? 155.292 159.987 220.151 1.00 134.79 ? 122 PRO L CG  1 
ATOM 3865 C CD  . PRO D 4 121 ? 155.220 161.157 219.212 1.00 134.79 ? 122 PRO L CD  1 
ATOM 3866 N N   . SER D 4 122 ? 151.053 159.662 220.640 1.00 142.55 ? 123 SER L N   1 
ATOM 3867 C CA  . SER D 4 122 ? 150.150 159.863 221.759 1.00 142.55 ? 123 SER L CA  1 
ATOM 3868 C C   . SER D 4 122 ? 150.709 159.211 223.018 1.00 142.55 ? 123 SER L C   1 
ATOM 3869 O O   . SER D 4 122 ? 151.593 158.343 222.967 1.00 142.55 ? 123 SER L O   1 
ATOM 3870 C CB  . SER D 4 122 ? 148.768 159.297 221.449 1.00 142.55 ? 123 SER L CB  1 
ATOM 3871 O OG  . SER D 4 122 ? 148.823 157.892 221.296 1.00 142.55 ? 123 SER L OG  1 
ATOM 3872 N N   . ASP D 4 123 ? 150.179 159.640 224.165 1.00 147.69 ? 124 ASP L N   1 
ATOM 3873 C CA  . ASP D 4 123 ? 150.626 159.089 225.441 1.00 147.69 ? 124 ASP L CA  1 
ATOM 3874 C C   . ASP D 4 123 ? 150.331 157.597 225.529 1.00 147.69 ? 124 ASP L C   1 
ATOM 3875 O O   . ASP D 4 123 ? 151.132 156.829 226.077 1.00 147.69 ? 124 ASP L O   1 
ATOM 3876 C CB  . ASP D 4 123 ? 149.962 159.836 226.598 1.00 147.69 ? 124 ASP L CB  1 
ATOM 3877 C CG  . ASP D 4 123 ? 150.425 161.274 226.706 1.00 147.69 ? 124 ASP L CG  1 
ATOM 3878 O OD1 . ASP D 4 123 ? 151.302 161.679 225.915 1.00 147.69 ? 124 ASP L OD1 1 
ATOM 3879 O OD2 . ASP D 4 123 ? 149.912 162.002 227.582 1.00 147.69 ? 124 ASP L OD2 1 
ATOM 3880 N N   . GLU D 4 124 ? 149.183 157.171 224.995 1.00 147.50 ? 125 GLU L N   1 
ATOM 3881 C CA  . GLU D 4 124 ? 148.822 155.757 225.033 1.00 147.50 ? 125 GLU L CA  1 
ATOM 3882 C C   . GLU D 4 124 ? 149.832 154.906 224.276 1.00 147.50 ? 125 GLU L C   1 
ATOM 3883 O O   . GLU D 4 124 ? 150.270 153.852 224.768 1.00 147.50 ? 125 GLU L O   1 
ATOM 3884 C CB  . GLU D 4 124 ? 147.420 155.551 224.460 1.00 30.00  ? 125 GLU L CB  1 
ATOM 3885 C CG  . GLU D 4 124 ? 146.307 156.160 225.296 1.00 30.00  ? 125 GLU L CG  1 
ATOM 3886 C CD  . GLU D 4 124 ? 144.942 155.996 224.658 1.00 30.00  ? 125 GLU L CD  1 
ATOM 3887 O OE1 . GLU D 4 124 ? 144.879 155.579 223.483 1.00 30.00  ? 125 GLU L OE1 1 
ATOM 3888 O OE2 . GLU D 4 124 ? 143.930 156.285 225.332 1.00 30.00  ? 125 GLU L OE2 1 
ATOM 3889 N N   . GLN D 4 125 ? 150.228 155.347 223.081 1.00 144.02 ? 126 GLN L N   1 
ATOM 3890 C CA  . GLN D 4 125 ? 151.206 154.586 222.312 1.00 144.02 ? 126 GLN L CA  1 
ATOM 3891 C C   . GLN D 4 125 ? 152.553 154.557 223.017 1.00 144.02 ? 126 GLN L C   1 
ATOM 3892 O O   . GLN D 4 125 ? 153.269 153.550 222.962 1.00 144.02 ? 126 GLN L O   1 
ATOM 3893 C CB  . GLN D 4 125 ? 151.349 155.171 220.912 1.00 144.02 ? 126 GLN L CB  1 
ATOM 3894 C CG  . GLN D 4 125 ? 152.083 154.261 219.955 1.00 144.02 ? 126 GLN L CG  1 
ATOM 3895 C CD  . GLN D 4 125 ? 152.452 154.962 218.672 1.00 144.02 ? 126 GLN L CD  1 
ATOM 3896 O OE1 . GLN D 4 125 ? 153.002 156.061 218.690 1.00 144.02 ? 126 GLN L OE1 1 
ATOM 3897 N NE2 . GLN D 4 125 ? 152.140 154.337 217.546 1.00 144.02 ? 126 GLN L NE2 1 
ATOM 3898 N N   . LEU D 4 126 ? 152.919 155.661 223.673 1.00 145.11 ? 127 LEU L N   1 
ATOM 3899 C CA  . LEU D 4 126 ? 154.151 155.664 224.455 1.00 145.11 ? 127 LEU L CA  1 
ATOM 3900 C C   . LEU D 4 126 ? 154.086 154.654 225.593 1.00 145.11 ? 127 LEU L C   1 
ATOM 3901 O O   . LEU D 4 126 ? 155.081 153.986 225.897 1.00 145.11 ? 127 LEU L O   1 
ATOM 3902 C CB  . LEU D 4 126 ? 154.418 157.065 224.999 1.00 145.11 ? 127 LEU L CB  1 
ATOM 3903 C CG  . LEU D 4 126 ? 154.965 158.102 224.020 1.00 145.11 ? 127 LEU L CG  1 
ATOM 3904 C CD1 . LEU D 4 126 ? 155.238 159.417 224.731 1.00 145.11 ? 127 LEU L CD1 1 
ATOM 3905 C CD2 . LEU D 4 126 ? 156.225 157.580 223.370 1.00 145.11 ? 127 LEU L CD2 1 
ATOM 3906 N N   . LYS D 4 127 ? 152.927 154.539 226.245 1.00 146.61 ? 128 LYS L N   1 
ATOM 3907 C CA  . LYS D 4 127 ? 152.783 153.565 227.323 1.00 146.61 ? 128 LYS L CA  1 
ATOM 3908 C C   . LYS D 4 127 ? 152.874 152.132 226.810 1.00 146.61 ? 128 LYS L C   1 
ATOM 3909 O O   . LYS D 4 127 ? 153.186 151.221 227.586 1.00 146.61 ? 128 LYS L O   1 
ATOM 3910 C CB  . LYS D 4 127 ? 151.464 153.793 228.063 1.00 146.61 ? 128 LYS L CB  1 
ATOM 3911 C CG  . LYS D 4 127 ? 151.446 155.085 228.861 1.00 146.61 ? 128 LYS L CG  1 
ATOM 3912 C CD  . LYS D 4 127 ? 150.123 155.303 229.571 1.00 146.61 ? 128 LYS L CD  1 
ATOM 3913 C CE  . LYS D 4 127 ? 150.143 156.607 230.353 1.00 146.61 ? 128 LYS L CE  1 
ATOM 3914 N NZ  . LYS D 4 127 ? 148.848 156.875 231.035 1.00 146.61 ? 128 LYS L NZ  1 
ATOM 3915 N N   . SER D 4 128 ? 152.599 151.919 225.522 1.00 146.99 ? 129 SER L N   1 
ATOM 3916 C CA  . SER D 4 128 ? 152.764 150.597 224.922 1.00 146.99 ? 129 SER L CA  1 
ATOM 3917 C C   . SER D 4 128 ? 154.197 150.302 224.492 1.00 146.99 ? 129 SER L C   1 
ATOM 3918 O O   . SER D 4 128 ? 154.483 149.165 224.103 1.00 146.99 ? 129 SER L O   1 
ATOM 3919 C CB  . SER D 4 128 ? 151.829 150.449 223.721 1.00 146.99 ? 129 SER L CB  1 
ATOM 3920 O OG  . SER D 4 128 ? 150.475 150.460 224.132 1.00 146.99 ? 129 SER L OG  1 
ATOM 3921 N N   . GLY D 4 129 ? 155.096 151.280 224.549 1.00 148.01 ? 130 GLY L N   1 
ATOM 3922 C CA  . GLY D 4 129 ? 156.497 151.057 224.256 1.00 148.01 ? 130 GLY L CA  1 
ATOM 3923 C C   . GLY D 4 129 ? 156.971 151.437 222.869 1.00 148.01 ? 130 GLY L C   1 
ATOM 3924 O O   . GLY D 4 129 ? 158.127 151.154 222.536 1.00 148.01 ? 130 GLY L O   1 
ATOM 3925 N N   . THR D 4 130 ? 156.130 152.071 222.055 1.00 146.81 ? 131 THR L N   1 
ATOM 3926 C CA  . THR D 4 130 ? 156.497 152.470 220.704 1.00 146.81 ? 131 THR L CA  1 
ATOM 3927 C C   . THR D 4 130 ? 156.062 153.908 220.466 1.00 146.81 ? 131 THR L C   1 
ATOM 3928 O O   . THR D 4 130 ? 154.986 154.317 220.905 1.00 146.81 ? 131 THR L O   1 
ATOM 3929 C CB  . THR D 4 130 ? 155.849 151.557 219.660 1.00 146.81 ? 131 THR L CB  1 
ATOM 3930 O OG1 . THR D 4 130 ? 155.982 150.192 220.071 1.00 146.81 ? 131 THR L OG1 1 
ATOM 3931 C CG2 . THR D 4 130 ? 156.512 151.741 218.302 1.00 146.81 ? 131 THR L CG2 1 
ATOM 3932 N N   . ALA D 4 131 ? 156.902 154.673 219.774 1.00 141.68 ? 132 ALA L N   1 
ATOM 3933 C CA  . ALA D 4 131 ? 156.622 156.070 219.461 1.00 141.68 ? 132 ALA L CA  1 
ATOM 3934 C C   . ALA D 4 131 ? 156.635 156.239 217.951 1.00 141.68 ? 132 ALA L C   1 
ATOM 3935 O O   . ALA D 4 131 ? 157.686 156.115 217.315 1.00 141.68 ? 132 ALA L O   1 
ATOM 3936 C CB  . ALA D 4 131 ? 157.641 156.994 220.119 1.00 141.68 ? 132 ALA L CB  1 
ATOM 3937 N N   . SER D 4 132 ? 155.474 156.527 217.379 1.00 134.30 ? 133 SER L N   1 
ATOM 3938 C CA  . SER D 4 132 ? 155.348 156.788 215.954 1.00 134.30 ? 133 SER L CA  1 
ATOM 3939 C C   . SER D 4 132 ? 155.059 158.269 215.751 1.00 134.30 ? 133 SER L C   1 
ATOM 3940 O O   . SER D 4 132 ? 154.031 158.776 216.211 1.00 134.30 ? 133 SER L O   1 
ATOM 3941 C CB  . SER D 4 132 ? 154.250 155.923 215.340 1.00 134.30 ? 133 SER L CB  1 
ATOM 3942 O OG  . SER D 4 132 ? 154.435 154.564 215.685 1.00 134.30 ? 133 SER L OG  1 
ATOM 3943 N N   . VAL D 4 133 ? 155.970 158.955 215.073 1.00 123.17 ? 134 VAL L N   1 
ATOM 3944 C CA  . VAL D 4 133 ? 155.820 160.360 214.723 1.00 123.17 ? 134 VAL L CA  1 
ATOM 3945 C C   . VAL D 4 133 ? 155.399 160.428 213.264 1.00 123.17 ? 134 VAL L C   1 
ATOM 3946 O O   . VAL D 4 133 ? 156.023 159.795 212.405 1.00 123.17 ? 134 VAL L O   1 
ATOM 3947 C CB  . VAL D 4 133 ? 157.130 161.130 214.959 1.00 123.17 ? 134 VAL L CB  1 
ATOM 3948 C CG1 . VAL D 4 133 ? 156.921 162.606 214.735 1.00 123.17 ? 134 VAL L CG1 1 
ATOM 3949 C CG2 . VAL D 4 133 ? 157.648 160.872 216.363 1.00 123.17 ? 134 VAL L CG2 1 
ATOM 3950 N N   . VAL D 4 134 ? 154.352 161.193 212.970 1.00 112.08 ? 135 VAL L N   1 
ATOM 3951 C CA  . VAL D 4 134 ? 153.699 161.120 211.665 1.00 112.08 ? 135 VAL L CA  1 
ATOM 3952 C C   . VAL D 4 134 ? 153.798 162.467 210.958 1.00 112.08 ? 135 VAL L C   1 
ATOM 3953 O O   . VAL D 4 134 ? 153.499 163.507 211.548 1.00 112.08 ? 135 VAL L O   1 
ATOM 3954 C CB  . VAL D 4 134 ? 152.234 160.669 211.800 1.00 112.08 ? 135 VAL L CB  1 
ATOM 3955 C CG1 . VAL D 4 134 ? 151.440 161.024 210.558 1.00 112.08 ? 135 VAL L CG1 1 
ATOM 3956 C CG2 . VAL D 4 134 ? 152.178 159.179 212.045 1.00 112.08 ? 135 VAL L CG2 1 
ATOM 3957 N N   . CYS D 4 135 ? 154.211 162.447 209.694 1.00 106.51 ? 136 CYS L N   1 
ATOM 3958 C CA  . CYS D 4 135 ? 154.244 163.640 208.858 1.00 106.51 ? 136 CYS L CA  1 
ATOM 3959 C C   . CYS D 4 135 ? 153.212 163.494 207.755 1.00 106.51 ? 136 CYS L C   1 
ATOM 3960 O O   . CYS D 4 135 ? 153.122 162.439 207.120 1.00 106.51 ? 136 CYS L O   1 
ATOM 3961 C CB  . CYS D 4 135 ? 155.631 163.866 208.258 1.00 106.51 ? 136 CYS L CB  1 
ATOM 3962 S SG  . CYS D 4 135 ? 155.852 165.466 207.476 1.00 106.51 ? 136 CYS L SG  1 
ATOM 3963 N N   . LEU D 4 136 ? 152.437 164.550 207.529 1.00 95.01  ? 137 LEU L N   1 
ATOM 3964 C CA  . LEU D 4 136 ? 151.306 164.506 206.615 1.00 95.01  ? 137 LEU L CA  1 
ATOM 3965 C C   . LEU D 4 136 ? 151.417 165.611 205.576 1.00 95.01  ? 137 LEU L C   1 
ATOM 3966 O O   . LEU D 4 136 ? 151.608 166.779 205.926 1.00 95.01  ? 137 LEU L O   1 
ATOM 3967 C CB  . LEU D 4 136 ? 149.992 164.643 207.376 1.00 95.01  ? 137 LEU L CB  1 
ATOM 3968 C CG  . LEU D 4 136 ? 148.792 164.896 206.474 1.00 95.01  ? 137 LEU L CG  1 
ATOM 3969 C CD1 . LEU D 4 136 ? 148.542 163.683 205.610 1.00 95.01  ? 137 LEU L CD1 1 
ATOM 3970 C CD2 . LEU D 4 136 ? 147.576 165.246 207.295 1.00 95.01  ? 137 LEU L CD2 1 
ATOM 3971 N N   . LEU D 4 137 ? 151.288 165.233 204.305 1.00 87.59  ? 138 LEU L N   1 
ATOM 3972 C CA  . LEU D 4 137 ? 151.225 166.160 203.178 1.00 87.59  ? 138 LEU L CA  1 
ATOM 3973 C C   . LEU D 4 137 ? 149.843 166.027 202.555 1.00 87.59  ? 138 LEU L C   1 
ATOM 3974 O O   . LEU D 4 137 ? 149.509 164.979 201.996 1.00 87.59  ? 138 LEU L O   1 
ATOM 3975 C CB  . LEU D 4 137 ? 152.309 165.861 202.150 1.00 87.59  ? 138 LEU L CB  1 
ATOM 3976 C CG  . LEU D 4 137 ? 153.688 165.475 202.670 1.00 87.59  ? 138 LEU L CG  1 
ATOM 3977 C CD1 . LEU D 4 137 ? 154.650 165.349 201.509 1.00 87.59  ? 138 LEU L CD1 1 
ATOM 3978 C CD2 . LEU D 4 137 ? 154.177 166.489 203.663 1.00 87.59  ? 138 LEU L CD2 1 
ATOM 3979 N N   . ASN D 4 138 ? 149.047 167.081 202.654 1.00 87.21  ? 139 ASN L N   1 
ATOM 3980 C CA  . ASN D 4 138 ? 147.694 167.097 202.122 1.00 87.21  ? 139 ASN L CA  1 
ATOM 3981 C C   . ASN D 4 138 ? 147.658 167.840 200.795 1.00 87.21  ? 139 ASN L C   1 
ATOM 3982 O O   . ASN D 4 138 ? 148.088 168.993 200.713 1.00 87.21  ? 139 ASN L O   1 
ATOM 3983 C CB  . ASN D 4 138 ? 146.730 167.757 203.102 1.00 87.21  ? 139 ASN L CB  1 
ATOM 3984 C CG  . ASN D 4 138 ? 146.405 166.874 204.270 1.00 87.21  ? 139 ASN L CG  1 
ATOM 3985 O OD1 . ASN D 4 138 ? 146.440 165.651 204.160 1.00 87.21  ? 139 ASN L OD1 1 
ATOM 3986 N ND2 . ASN D 4 138 ? 146.079 167.482 205.402 1.00 87.21  ? 139 ASN L ND2 1 
ATOM 3987 N N   . ASN D 4 139 ? 147.136 167.173 199.769 1.00 81.69  ? 140 ASN L N   1 
ATOM 3988 C CA  . ASN D 4 139 ? 146.725 167.809 198.519 1.00 81.69  ? 140 ASN L CA  1 
ATOM 3989 C C   . ASN D 4 139 ? 147.901 168.431 197.764 1.00 81.69  ? 140 ASN L C   1 
ATOM 3990 O O   . ASN D 4 139 ? 147.942 169.633 197.498 1.00 81.69  ? 140 ASN L O   1 
ATOM 3991 C CB  . ASN D 4 139 ? 145.629 168.842 198.796 1.00 81.69  ? 140 ASN L CB  1 
ATOM 3992 C CG  . ASN D 4 139 ? 144.404 168.218 199.415 1.00 81.69  ? 140 ASN L CG  1 
ATOM 3993 O OD1 . ASN D 4 139 ? 144.022 167.110 199.053 1.00 81.69  ? 140 ASN L OD1 1 
ATOM 3994 N ND2 . ASN D 4 139 ? 143.792 168.911 200.366 1.00 81.69  ? 140 ASN L ND2 1 
ATOM 3995 N N   . PHE D 4 140 ? 148.861 167.583 197.409 1.00 74.95  ? 141 PHE L N   1 
ATOM 3996 C CA  . PHE D 4 140 ? 149.859 167.922 196.407 1.00 74.95  ? 141 PHE L CA  1 
ATOM 3997 C C   . PHE D 4 140 ? 149.371 167.407 195.058 1.00 74.95  ? 141 PHE L C   1 
ATOM 3998 O O   . PHE D 4 140 ? 149.045 166.228 194.923 1.00 74.95  ? 141 PHE L O   1 
ATOM 3999 C CB  . PHE D 4 140 ? 151.224 167.322 196.758 1.00 74.95  ? 141 PHE L CB  1 
ATOM 4000 C CG  . PHE D 4 140 ? 152.335 167.736 195.824 1.00 74.95  ? 141 PHE L CG  1 
ATOM 4001 C CD1 . PHE D 4 140 ? 152.430 169.038 195.373 1.00 74.95  ? 141 PHE L CD1 1 
ATOM 4002 C CD2 . PHE D 4 140 ? 153.300 166.828 195.418 1.00 74.95  ? 141 PHE L CD2 1 
ATOM 4003 C CE1 . PHE D 4 140 ? 153.453 169.427 194.525 1.00 74.95  ? 141 PHE L CE1 1 
ATOM 4004 C CE2 . PHE D 4 140 ? 154.323 167.212 194.564 1.00 74.95  ? 141 PHE L CE2 1 
ATOM 4005 C CZ  . PHE D 4 140 ? 154.394 168.513 194.119 1.00 74.95  ? 141 PHE L CZ  1 
ATOM 4006 N N   . TYR D 4 141 ? 149.296 168.300 194.069 1.00 75.76  ? 142 TYR L N   1 
ATOM 4007 C CA  . TYR D 4 141 ? 148.774 167.903 192.764 1.00 75.76  ? 142 TYR L CA  1 
ATOM 4008 C C   . TYR D 4 141 ? 149.627 166.830 192.099 1.00 75.76  ? 142 TYR L C   1 
ATOM 4009 O O   . TYR D 4 141 ? 149.067 165.797 191.690 1.00 75.76  ? 142 TYR L O   1 
ATOM 4010 C CB  . TYR D 4 141 ? 148.608 169.140 191.874 1.00 75.76  ? 142 TYR L CB  1 
ATOM 4011 C CG  . TYR D 4 141 ? 147.213 169.731 191.830 1.00 75.76  ? 142 TYR L CG  1 
ATOM 4012 C CD1 . TYR D 4 141 ? 146.149 169.010 191.313 1.00 75.76  ? 142 TYR L CD1 1 
ATOM 4013 C CD2 . TYR D 4 141 ? 146.970 171.021 192.272 1.00 75.76  ? 142 TYR L CD2 1 
ATOM 4014 C CE1 . TYR D 4 141 ? 144.884 169.551 191.249 1.00 75.76  ? 142 TYR L CE1 1 
ATOM 4015 C CE2 . TYR D 4 141 ? 145.706 171.570 192.219 1.00 75.76  ? 142 TYR L CE2 1 
ATOM 4016 C CZ  . TYR D 4 141 ? 144.666 170.830 191.707 1.00 75.76  ? 142 TYR L CZ  1 
ATOM 4017 O OH  . TYR D 4 141 ? 143.402 171.371 191.648 1.00 75.76  ? 142 TYR L OH  1 
ATOM 4018 N N   . PRO D 4 142 ? 150.942 166.979 191.950 1.00 77.10  ? 143 PRO L N   1 
ATOM 4019 C CA  . PRO D 4 142 ? 151.759 165.815 191.592 1.00 77.10  ? 143 PRO L CA  1 
ATOM 4020 C C   . PRO D 4 142 ? 151.855 164.852 192.769 1.00 77.10  ? 143 PRO L C   1 
ATOM 4021 O O   . PRO D 4 142 ? 151.393 165.124 193.877 1.00 77.10  ? 143 PRO L O   1 
ATOM 4022 C CB  . PRO D 4 142 ? 153.121 166.419 191.233 1.00 77.10  ? 143 PRO L CB  1 
ATOM 4023 C CG  . PRO D 4 142 ? 152.842 167.851 190.951 1.00 77.10  ? 143 PRO L CG  1 
ATOM 4024 C CD  . PRO D 4 142 ? 151.746 168.214 191.905 1.00 77.10  ? 143 PRO L CD  1 
ATOM 4025 N N   . ARG D 4 143 ? 152.458 163.693 192.508 1.00 85.03  ? 144 ARG L N   1 
ATOM 4026 C CA  . ARG D 4 143 ? 152.639 162.673 193.534 1.00 85.03  ? 144 ARG L CA  1 
ATOM 4027 C C   . ARG D 4 143 ? 154.110 162.363 193.789 1.00 85.03  ? 144 ARG L C   1 
ATOM 4028 O O   . ARG D 4 143 ? 154.430 161.300 194.331 1.00 85.03  ? 144 ARG L O   1 
ATOM 4029 C CB  . ARG D 4 143 ? 151.884 161.399 193.157 1.00 85.03  ? 144 ARG L CB  1 
ATOM 4030 C CG  . ARG D 4 143 ? 152.432 160.680 191.941 1.00 85.03  ? 144 ARG L CG  1 
ATOM 4031 C CD  . ARG D 4 143 ? 151.793 159.311 191.786 1.00 85.03  ? 144 ARG L CD  1 
ATOM 4032 N NE  . ARG D 4 143 ? 152.378 158.559 190.682 1.00 85.03  ? 144 ARG L NE  1 
ATOM 4033 C CZ  . ARG D 4 143 ? 153.454 157.791 190.788 1.00 85.03  ? 144 ARG L CZ  1 
ATOM 4034 N NH1 . ARG D 4 143 ? 154.081 157.637 191.942 1.00 85.03  ? 144 ARG L NH1 1 
ATOM 4035 N NH2 . ARG D 4 143 ? 153.912 157.164 189.709 1.00 85.03  ? 144 ARG L NH2 1 
ATOM 4036 N N   . GLU D 4 144 ? 155.015 163.267 193.420 1.00 84.84  ? 145 GLU L N   1 
ATOM 4037 C CA  . GLU D 4 144 ? 156.443 163.046 193.589 1.00 84.84  ? 145 GLU L CA  1 
ATOM 4038 C C   . GLU D 4 144 ? 157.018 163.747 194.816 1.00 84.84  ? 145 GLU L C   1 
ATOM 4039 O O   . GLU D 4 144 ? 158.220 164.024 194.845 1.00 84.84  ? 145 GLU L O   1 
ATOM 4040 C CB  . GLU D 4 144 ? 157.201 163.489 192.337 1.00 84.84  ? 145 GLU L CB  1 
ATOM 4041 C CG  . GLU D 4 144 ? 156.951 162.620 191.109 1.00 84.84  ? 145 GLU L CG  1 
ATOM 4042 C CD  . GLU D 4 144 ? 155.714 163.038 190.336 1.00 84.84  ? 145 GLU L CD  1 
ATOM 4043 O OE1 . GLU D 4 144 ? 155.403 164.248 190.333 1.00 84.84  ? 145 GLU L OE1 1 
ATOM 4044 O OE2 . GLU D 4 144 ? 155.054 162.163 189.732 1.00 84.84  ? 145 GLU L OE2 1 
ATOM 4045 N N   . ALA D 4 145 ? 156.195 164.049 195.818 1.00 82.09  ? 146 ALA L N   1 
ATOM 4046 C CA  . ALA D 4 145 ? 156.680 164.734 197.013 1.00 82.09  ? 146 ALA L CA  1 
ATOM 4047 C C   . ALA D 4 145 ? 157.687 163.875 197.774 1.00 82.09  ? 146 ALA L C   1 
ATOM 4048 O O   . ALA D 4 145 ? 157.583 162.647 197.817 1.00 82.09  ? 146 ALA L O   1 
ATOM 4049 C CB  . ALA D 4 145 ? 155.509 165.095 197.925 1.00 82.09  ? 146 ALA L CB  1 
ATOM 4050 N N   . LYS D 4 146 ? 158.667 164.534 198.391 1.00 91.18  ? 147 LYS L N   1 
ATOM 4051 C CA  . LYS D 4 146 ? 159.697 163.859 199.169 1.00 91.18  ? 147 LYS L CA  1 
ATOM 4052 C C   . LYS D 4 146 ? 159.665 164.319 200.622 1.00 91.18  ? 147 LYS L C   1 
ATOM 4053 O O   . LYS D 4 146 ? 159.577 165.520 200.903 1.00 91.18  ? 147 LYS L O   1 
ATOM 4054 C CB  . LYS D 4 146 ? 161.088 164.110 198.591 1.00 91.18  ? 147 LYS L CB  1 
ATOM 4055 C CG  . LYS D 4 146 ? 162.200 163.536 199.440 1.00 91.18  ? 147 LYS L CG  1 
ATOM 4056 C CD  . LYS D 4 146 ? 163.532 163.633 198.741 1.00 91.18  ? 147 LYS L CD  1 
ATOM 4057 C CE  . LYS D 4 146 ? 164.624 163.007 199.582 1.00 91.18  ? 147 LYS L CE  1 
ATOM 4058 N NZ  . LYS D 4 146 ? 165.932 163.008 198.878 1.00 91.18  ? 147 LYS L NZ  1 
ATOM 4059 N N   . VAL D 4 147 ? 159.757 163.355 201.538 1.00 99.27  ? 148 VAL L N   1 
ATOM 4060 C CA  . VAL D 4 147 ? 159.732 163.594 202.977 1.00 99.27  ? 148 VAL L CA  1 
ATOM 4061 C C   . VAL D 4 147 ? 161.011 163.040 203.588 1.00 99.27  ? 148 VAL L C   1 
ATOM 4062 O O   . VAL D 4 147 ? 161.388 161.895 203.316 1.00 99.27  ? 148 VAL L O   1 
ATOM 4063 C CB  . VAL D 4 147 ? 158.499 162.955 203.636 1.00 99.27  ? 148 VAL L CB  1 
ATOM 4064 C CG1 . VAL D 4 147 ? 158.700 162.842 205.131 1.00 99.27  ? 148 VAL L CG1 1 
ATOM 4065 C CG2 . VAL D 4 147 ? 157.273 163.773 203.336 1.00 99.27  ? 148 VAL L CG2 1 
ATOM 4066 N N   . GLN D 4 148 ? 161.671 163.847 204.414 1.00 108.82 ? 149 GLN L N   1 
ATOM 4067 C CA  . GLN D 4 148 ? 162.878 163.446 205.121 1.00 108.82 ? 149 GLN L CA  1 
ATOM 4068 C C   . GLN D 4 148 ? 162.678 163.694 206.608 1.00 108.82 ? 149 GLN L C   1 
ATOM 4069 O O   . GLN D 4 148 ? 162.388 164.823 207.021 1.00 108.82 ? 149 GLN L O   1 
ATOM 4070 C CB  . GLN D 4 148 ? 164.097 164.210 204.602 1.00 108.82 ? 149 GLN L CB  1 
ATOM 4071 C CG  . GLN D 4 148 ? 165.373 163.945 205.377 1.00 108.82 ? 149 GLN L CG  1 
ATOM 4072 C CD  . GLN D 4 148 ? 165.827 162.502 205.276 1.00 108.82 ? 149 GLN L CD  1 
ATOM 4073 O OE1 . GLN D 4 148 ? 165.845 161.918 204.192 1.00 108.82 ? 149 GLN L OE1 1 
ATOM 4074 N NE2 . GLN D 4 148 ? 166.192 161.918 206.410 1.00 108.82 ? 149 GLN L NE2 1 
ATOM 4075 N N   . TRP D 4 149 ? 162.832 162.647 207.411 1.00 117.94 ? 150 TRP L N   1 
ATOM 4076 C CA  . TRP D 4 149 ? 162.701 162.764 208.853 1.00 117.94 ? 150 TRP L CA  1 
ATOM 4077 C C   . TRP D 4 149 ? 164.021 163.183 209.482 1.00 117.94 ? 150 TRP L C   1 
ATOM 4078 O O   . TRP D 4 149 ? 165.087 162.694 209.101 1.00 117.94 ? 150 TRP L O   1 
ATOM 4079 C CB  . TRP D 4 149 ? 162.237 161.442 209.454 1.00 117.94 ? 150 TRP L CB  1 
ATOM 4080 C CG  . TRP D 4 149 ? 160.785 161.222 209.297 1.00 117.94 ? 150 TRP L CG  1 
ATOM 4081 C CD1 . TRP D 4 149 ? 160.166 160.448 208.366 1.00 117.94 ? 150 TRP L CD1 1 
ATOM 4082 C CD2 . TRP D 4 149 ? 159.754 161.794 210.097 1.00 117.94 ? 150 TRP L CD2 1 
ATOM 4083 N NE1 . TRP D 4 149 ? 158.808 160.498 208.540 1.00 117.94 ? 150 TRP L NE1 1 
ATOM 4084 C CE2 . TRP D 4 149 ? 158.530 161.323 209.597 1.00 117.94 ? 150 TRP L CE2 1 
ATOM 4085 C CE3 . TRP D 4 149 ? 159.747 162.662 211.190 1.00 117.94 ? 150 TRP L CE3 1 
ATOM 4086 C CZ2 . TRP D 4 149 ? 157.311 161.685 210.155 1.00 117.94 ? 150 TRP L CZ2 1 
ATOM 4087 C CZ3 . TRP D 4 149 ? 158.540 163.024 211.737 1.00 117.94 ? 150 TRP L CZ3 1 
ATOM 4088 C CH2 . TRP D 4 149 ? 157.336 162.537 211.221 1.00 117.94 ? 150 TRP L CH2 1 
ATOM 4089 N N   . LYS D 4 150 ? 163.943 164.091 210.449 1.00 129.21 ? 151 LYS L N   1 
ATOM 4090 C CA  . LYS D 4 150 ? 165.106 164.520 211.207 1.00 129.21 ? 151 LYS L CA  1 
ATOM 4091 C C   . LYS D 4 150 ? 164.785 164.464 212.690 1.00 129.21 ? 151 LYS L C   1 
ATOM 4092 O O   . LYS D 4 150 ? 163.684 164.828 213.115 1.00 129.21 ? 151 LYS L O   1 
ATOM 4093 C CB  . LYS D 4 150 ? 165.539 165.936 210.828 1.00 129.21 ? 151 LYS L CB  1 
ATOM 4094 C CG  . LYS D 4 150 ? 166.173 166.057 209.458 1.00 129.21 ? 151 LYS L CG  1 
ATOM 4095 C CD  . LYS D 4 150 ? 166.530 167.503 209.178 1.00 129.21 ? 151 LYS L CD  1 
ATOM 4096 C CE  . LYS D 4 150 ? 167.193 167.674 207.827 1.00 129.21 ? 151 LYS L CE  1 
ATOM 4097 N NZ  . LYS D 4 150 ? 167.422 169.116 207.532 1.00 129.21 ? 151 LYS L NZ  1 
ATOM 4098 N N   . VAL D 4 151 ? 165.753 163.997 213.468 1.00 140.46 ? 152 VAL L N   1 
ATOM 4099 C CA  . VAL D 4 151 ? 165.640 163.936 214.922 1.00 140.46 ? 152 VAL L CA  1 
ATOM 4100 C C   . VAL D 4 151 ? 166.877 164.612 215.490 1.00 140.46 ? 152 VAL L C   1 
ATOM 4101 O O   . VAL D 4 151 ? 167.993 164.093 215.341 1.00 140.46 ? 152 VAL L O   1 
ATOM 4102 C CB  . VAL D 4 151 ? 165.517 162.497 215.435 1.00 140.46 ? 152 VAL L CB  1 
ATOM 4103 C CG1 . VAL D 4 151 ? 165.290 162.488 216.925 1.00 140.46 ? 152 VAL L CG1 1 
ATOM 4104 C CG2 . VAL D 4 151 ? 164.384 161.775 214.729 1.00 140.46 ? 152 VAL L CG2 1 
ATOM 4105 N N   . ASP D 4 152 ? 166.687 165.756 216.147 1.00 144.87 ? 153 ASP L N   1 
ATOM 4106 C CA  . ASP D 4 152 ? 167.791 166.583 216.630 1.00 144.87 ? 153 ASP L CA  1 
ATOM 4107 C C   . ASP D 4 152 ? 168.793 166.857 215.512 1.00 144.87 ? 153 ASP L C   1 
ATOM 4108 O O   . ASP D 4 152 ? 170.006 166.725 215.684 1.00 144.87 ? 153 ASP L O   1 
ATOM 4109 C CB  . ASP D 4 152 ? 168.478 165.943 217.837 1.00 144.87 ? 153 ASP L CB  1 
ATOM 4110 C CG  . ASP D 4 152 ? 167.680 166.108 219.111 1.00 144.87 ? 153 ASP L CG  1 
ATOM 4111 O OD1 . ASP D 4 152 ? 166.861 167.050 219.179 1.00 144.87 ? 153 ASP L OD1 1 
ATOM 4112 O OD2 . ASP D 4 152 ? 167.874 165.299 220.043 1.00 144.87 ? 153 ASP L OD2 1 
ATOM 4113 N N   . ASN D 4 153 ? 168.261 167.215 214.342 1.00 141.82 ? 154 ASN L N   1 
ATOM 4114 C CA  . ASN D 4 153 ? 169.010 167.564 213.136 1.00 141.82 ? 154 ASN L CA  1 
ATOM 4115 C C   . ASN D 4 153 ? 169.767 166.385 212.541 1.00 141.82 ? 154 ASN L C   1 
ATOM 4116 O O   . ASN D 4 153 ? 170.528 166.570 211.583 1.00 141.82 ? 154 ASN L O   1 
ATOM 4117 C CB  . ASN D 4 153 ? 169.984 168.723 213.382 1.00 141.82 ? 154 ASN L CB  1 
ATOM 4118 C CG  . ASN D 4 153 ? 169.274 170.000 213.782 1.00 141.82 ? 154 ASN L CG  1 
ATOM 4119 O OD1 . ASN D 4 153 ? 168.160 170.266 213.333 1.00 141.82 ? 154 ASN L OD1 1 
ATOM 4120 N ND2 . ASN D 4 153 ? 169.913 170.796 214.633 1.00 141.82 ? 154 ASN L ND2 1 
ATOM 4121 N N   . ALA D 4 154 ? 169.588 165.180 213.077 1.00 136.70 ? 155 ALA L N   1 
ATOM 4122 C CA  . ALA D 4 154 ? 170.182 163.993 212.482 1.00 136.70 ? 155 ALA L CA  1 
ATOM 4123 C C   . ALA D 4 154 ? 169.230 163.390 211.456 1.00 136.70 ? 155 ALA L C   1 
ATOM 4124 O O   . ALA D 4 154 ? 168.009 163.412 211.638 1.00 136.70 ? 155 ALA L O   1 
ATOM 4125 C CB  . ALA D 4 154 ? 170.521 162.963 213.559 1.00 136.70 ? 155 ALA L CB  1 
ATOM 4126 N N   . LEU D 4 155 ? 169.795 162.856 210.379 1.00 132.79 ? 156 LEU L N   1 
ATOM 4127 C CA  . LEU D 4 155 ? 168.988 162.265 209.322 1.00 132.79 ? 156 LEU L CA  1 
ATOM 4128 C C   . LEU D 4 155 ? 168.514 160.873 209.718 1.00 132.79 ? 156 LEU L C   1 
ATOM 4129 O O   . LEU D 4 155 ? 169.261 160.090 210.311 1.00 132.79 ? 156 LEU L O   1 
ATOM 4130 C CB  . LEU D 4 155 ? 169.783 162.198 208.019 1.00 132.79 ? 156 LEU L CB  1 
ATOM 4131 C CG  . LEU D 4 155 ? 170.101 163.550 207.382 1.00 132.79 ? 156 LEU L CG  1 
ATOM 4132 C CD1 . LEU D 4 155 ? 170.908 163.371 206.108 1.00 132.79 ? 156 LEU L CD1 1 
ATOM 4133 C CD2 . LEU D 4 155 ? 168.815 164.312 207.107 1.00 132.79 ? 156 LEU L CD2 1 
ATOM 4134 N N   . GLN D 4 156 ? 167.265 160.568 209.386 1.00 133.09 ? 157 GLN L N   1 
ATOM 4135 C CA  . GLN D 4 156 ? 166.685 159.265 209.669 1.00 133.09 ? 157 GLN L CA  1 
ATOM 4136 C C   . GLN D 4 156 ? 166.716 158.381 208.428 1.00 133.09 ? 157 GLN L C   1 
ATOM 4137 O O   . GLN D 4 156 ? 166.533 158.857 207.303 1.00 133.09 ? 157 GLN L O   1 
ATOM 4138 C CB  . GLN D 4 156 ? 165.250 159.403 210.175 1.00 133.09 ? 157 GLN L CB  1 
ATOM 4139 C CG  . GLN D 4 156 ? 165.139 160.060 211.541 1.00 133.09 ? 157 GLN L CG  1 
ATOM 4140 C CD  . GLN D 4 156 ? 165.881 159.292 212.613 1.00 133.09 ? 157 GLN L CD  1 
ATOM 4141 O OE1 . GLN D 4 156 ? 165.632 158.106 212.827 1.00 133.09 ? 157 GLN L OE1 1 
ATOM 4142 N NE2 . GLN D 4 156 ? 166.806 159.962 213.289 1.00 133.09 ? 157 GLN L NE2 1 
ATOM 4143 N N   . SER D 4 157 ? 166.942 157.087 208.645 1.00 134.72 ? 158 SER L N   1 
ATOM 4144 C CA  . SER D 4 157 ? 167.023 156.128 207.551 1.00 134.72 ? 158 SER L CA  1 
ATOM 4145 C C   . SER D 4 157 ? 166.734 154.740 208.097 1.00 134.72 ? 158 SER L C   1 
ATOM 4146 O O   . SER D 4 157 ? 167.375 154.305 209.058 1.00 134.72 ? 158 SER L O   1 
ATOM 4147 C CB  . SER D 4 157 ? 168.404 156.166 206.886 1.00 134.72 ? 158 SER L CB  1 
ATOM 4148 O OG  . SER D 4 157 ? 168.487 155.239 205.817 1.00 134.72 ? 158 SER L OG  1 
ATOM 4149 N N   . GLY D 4 158 ? 165.772 154.052 207.486 1.00 132.57 ? 159 GLY L N   1 
ATOM 4150 C CA  . GLY D 4 158 ? 165.397 152.719 207.900 1.00 132.57 ? 159 GLY L CA  1 
ATOM 4151 C C   . GLY D 4 158 ? 164.345 152.656 208.985 1.00 132.57 ? 159 GLY L C   1 
ATOM 4152 O O   . GLY D 4 158 ? 163.762 151.585 209.198 1.00 132.57 ? 159 GLY L O   1 
ATOM 4153 N N   . ASN D 4 159 ? 164.076 153.764 209.671 1.00 129.45 ? 160 ASN L N   1 
ATOM 4154 C CA  . ASN D 4 159 ? 163.074 153.817 210.723 1.00 129.45 ? 160 ASN L CA  1 
ATOM 4155 C C   . ASN D 4 159 ? 161.773 154.447 210.253 1.00 129.45 ? 160 ASN L C   1 
ATOM 4156 O O   . ASN D 4 159 ? 160.912 154.756 211.081 1.00 129.45 ? 160 ASN L O   1 
ATOM 4157 C CB  . ASN D 4 159 ? 163.617 154.586 211.930 1.00 129.45 ? 160 ASN L CB  1 
ATOM 4158 C CG  . ASN D 4 159 ? 164.912 154.002 212.461 1.00 129.45 ? 160 ASN L CG  1 
ATOM 4159 O OD1 . ASN D 4 159 ? 165.046 152.787 212.606 1.00 129.45 ? 160 ASN L OD1 1 
ATOM 4160 N ND2 . ASN D 4 159 ? 165.877 154.869 212.752 1.00 129.45 ? 160 ASN L ND2 1 
ATOM 4161 N N   . SER D 4 160 ? 161.605 154.646 208.950 1.00 121.57 ? 161 SER L N   1 
ATOM 4162 C CA  . SER D 4 160 ? 160.472 155.393 208.434 1.00 121.57 ? 161 SER L CA  1 
ATOM 4163 C C   . SER D 4 160 ? 159.836 154.651 207.272 1.00 121.57 ? 161 SER L C   1 
ATOM 4164 O O   . SER D 4 160 ? 160.505 153.927 206.529 1.00 121.57 ? 161 SER L O   1 
ATOM 4165 C CB  . SER D 4 160 ? 160.891 156.803 207.996 1.00 121.57 ? 161 SER L CB  1 
ATOM 4166 O OG  . SER D 4 160 ? 161.966 156.751 207.077 1.00 121.57 ? 161 SER L OG  1 
ATOM 4167 N N   . GLN D 4 161 ? 158.535 154.856 207.115 1.00 115.48 ? 162 GLN L N   1 
ATOM 4168 C CA  . GLN D 4 161 ? 157.769 154.161 206.095 1.00 115.48 ? 162 GLN L CA  1 
ATOM 4169 C C   . GLN D 4 161 ? 156.675 155.087 205.584 1.00 115.48 ? 162 GLN L C   1 
ATOM 4170 O O   . GLN D 4 161 ? 155.987 155.737 206.375 1.00 115.48 ? 162 GLN L O   1 
ATOM 4171 C CB  . GLN D 4 161 ? 157.174 152.867 206.655 1.00 115.48 ? 162 GLN L CB  1 
ATOM 4172 C CG  . GLN D 4 161 ? 156.420 152.009 205.664 1.00 115.48 ? 162 GLN L CG  1 
ATOM 4173 C CD  . GLN D 4 161 ? 156.092 150.647 206.239 1.00 115.48 ? 162 GLN L CD  1 
ATOM 4174 O OE1 . GLN D 4 161 ? 156.051 150.471 207.457 1.00 115.48 ? 162 GLN L OE1 1 
ATOM 4175 N NE2 . GLN D 4 161 ? 155.874 149.671 205.368 1.00 115.48 ? 162 GLN L NE2 1 
ATOM 4176 N N   . GLU D 4 162 ? 156.512 155.130 204.265 1.00 101.85 ? 163 GLU L N   1 
ATOM 4177 C CA  . GLU D 4 162 ? 155.635 156.087 203.611 1.00 101.85 ? 163 GLU L CA  1 
ATOM 4178 C C   . GLU D 4 162 ? 154.434 155.387 202.990 1.00 101.85 ? 163 GLU L C   1 
ATOM 4179 O O   . GLU D 4 162 ? 154.484 154.202 202.655 1.00 101.85 ? 163 GLU L O   1 
ATOM 4180 C CB  . GLU D 4 162 ? 156.387 156.869 202.530 1.00 101.85 ? 163 GLU L CB  1 
ATOM 4181 C CG  . GLU D 4 162 ? 157.623 157.599 203.033 1.00 101.85 ? 163 GLU L CG  1 
ATOM 4182 C CD  . GLU D 4 162 ? 158.189 158.561 202.009 1.00 101.85 ? 163 GLU L CD  1 
ATOM 4183 O OE1 . GLU D 4 162 ? 157.628 158.640 200.894 1.00 101.85 ? 163 GLU L OE1 1 
ATOM 4184 O OE2 . GLU D 4 162 ? 159.192 159.240 202.320 1.00 101.85 ? 163 GLU L OE2 1 
ATOM 4185 N N   . SER D 4 163 ? 153.346 156.140 202.852 1.00 93.20  ? 164 SER L N   1 
ATOM 4186 C CA  . SER D 4 163 ? 152.143 155.665 202.184 1.00 93.20  ? 164 SER L CA  1 
ATOM 4187 C C   . SER D 4 163 ? 151.510 156.837 201.448 1.00 93.20  ? 164 SER L C   1 
ATOM 4188 O O   . SER D 4 163 ? 151.336 157.913 202.025 1.00 93.20  ? 164 SER L O   1 
ATOM 4189 C CB  . SER D 4 163 ? 151.156 155.058 203.181 1.00 93.20  ? 164 SER L CB  1 
ATOM 4190 O OG  . SER D 4 163 ? 150.041 154.499 202.515 1.00 93.20  ? 164 SER L OG  1 
ATOM 4191 N N   . VAL D 4 164 ? 151.164 156.624 200.182 1.00 84.45  ? 165 VAL L N   1 
ATOM 4192 C CA  . VAL D 4 164 ? 150.607 157.662 199.324 1.00 84.45  ? 165 VAL L CA  1 
ATOM 4193 C C   . VAL D 4 164 ? 149.236 157.211 198.846 1.00 84.45  ? 165 VAL L C   1 
ATOM 4194 O O   . VAL D 4 164 ? 149.072 156.070 198.399 1.00 84.45  ? 165 VAL L O   1 
ATOM 4195 C CB  . VAL D 4 164 ? 151.527 157.964 198.130 1.00 84.45  ? 165 VAL L CB  1 
ATOM 4196 C CG1 . VAL D 4 164 ? 150.936 159.063 197.266 1.00 84.45  ? 165 VAL L CG1 1 
ATOM 4197 C CG2 . VAL D 4 164 ? 152.916 158.336 198.612 1.00 84.45  ? 165 VAL L CG2 1 
ATOM 4198 N N   . THR D 4 165 ? 148.256 158.103 198.937 1.00 82.32  ? 166 THR L N   1 
ATOM 4199 C CA  . THR D 4 165 ? 146.917 157.788 198.475 1.00 82.32  ? 166 THR L CA  1 
ATOM 4200 C C   . THR D 4 165 ? 146.838 157.895 196.955 1.00 82.32  ? 166 THR L C   1 
ATOM 4201 O O   . THR D 4 165 ? 147.750 158.388 196.287 1.00 82.32  ? 166 THR L O   1 
ATOM 4202 C CB  . THR D 4 165 ? 145.888 158.721 199.113 1.00 82.32  ? 166 THR L CB  1 
ATOM 4203 O OG1 . THR D 4 165 ? 146.064 160.048 198.604 1.00 82.32  ? 166 THR L OG1 1 
ATOM 4204 C CG2 . THR D 4 165 ? 146.053 158.744 200.618 1.00 82.32  ? 166 THR L CG2 1 
ATOM 4205 N N   . GLU D 4 166 ? 145.724 157.417 196.410 1.00 83.35  ? 167 GLU L N   1 
ATOM 4206 C CA  . GLU D 4 166 ? 145.446 157.560 194.992 1.00 83.35  ? 167 GLU L CA  1 
ATOM 4207 C C   . GLU D 4 166 ? 144.976 158.981 194.687 1.00 83.35  ? 167 GLU L C   1 
ATOM 4208 O O   . GLU D 4 166 ? 144.652 159.766 195.582 1.00 83.35  ? 167 GLU L O   1 
ATOM 4209 C CB  . GLU D 4 166 ? 144.398 156.544 194.546 1.00 83.35  ? 167 GLU L CB  1 
ATOM 4210 C CG  . GLU D 4 166 ? 144.886 155.109 194.563 1.00 83.35  ? 167 GLU L CG  1 
ATOM 4211 C CD  . GLU D 4 166 ? 145.868 154.813 193.448 1.00 83.35  ? 167 GLU L CD  1 
ATOM 4212 O OE1 . GLU D 4 166 ? 145.706 155.382 192.347 1.00 83.35  ? 167 GLU L OE1 1 
ATOM 4213 O OE2 . GLU D 4 166 ? 146.799 154.012 193.675 1.00 83.35  ? 167 GLU L OE2 1 
ATOM 4214 N N   . GLN D 4 167 ? 144.953 159.311 193.399 1.00 79.31  ? 168 GLN L N   1 
ATOM 4215 C CA  . GLN D 4 167 ? 144.531 160.638 192.976 1.00 79.31  ? 168 GLN L CA  1 
ATOM 4216 C C   . GLN D 4 167 ? 143.086 160.886 193.386 1.00 79.31  ? 168 GLN L C   1 
ATOM 4217 O O   . GLN D 4 167 ? 142.217 160.032 193.187 1.00 79.31  ? 168 GLN L O   1 
ATOM 4218 C CB  . GLN D 4 167 ? 144.696 160.780 191.465 1.00 79.31  ? 168 GLN L CB  1 
ATOM 4219 C CG  . GLN D 4 167 ? 144.921 162.203 190.997 1.00 79.31  ? 168 GLN L CG  1 
ATOM 4220 C CD  . GLN D 4 167 ? 145.256 162.283 189.524 1.00 79.31  ? 168 GLN L CD  1 
ATOM 4221 O OE1 . GLN D 4 167 ? 145.033 161.335 188.774 1.00 79.31  ? 168 GLN L OE1 1 
ATOM 4222 N NE2 . GLN D 4 167 ? 145.801 163.417 189.101 1.00 79.31  ? 168 GLN L NE2 1 
ATOM 4223 N N   . ASP D 4 168 ? 142.835 162.057 193.970 1.00 91.86  ? 169 ASP L N   1 
ATOM 4224 C CA  . ASP D 4 168 ? 141.521 162.354 194.526 1.00 91.86  ? 169 ASP L CA  1 
ATOM 4225 C C   . ASP D 4 168 ? 140.459 162.371 193.435 1.00 91.86  ? 169 ASP L C   1 
ATOM 4226 O O   . ASP D 4 168 ? 140.662 162.926 192.353 1.00 91.86  ? 169 ASP L O   1 
ATOM 4227 C CB  . ASP D 4 168 ? 141.553 163.697 195.253 1.00 91.86  ? 169 ASP L CB  1 
ATOM 4228 C CG  . ASP D 4 168 ? 140.359 163.893 196.163 1.00 91.86  ? 169 ASP L CG  1 
ATOM 4229 O OD1 . ASP D 4 168 ? 140.341 163.294 197.259 1.00 91.86  ? 169 ASP L OD1 1 
ATOM 4230 O OD2 . ASP D 4 168 ? 139.439 164.646 195.784 1.00 91.86  ? 169 ASP L OD2 1 
ATOM 4231 N N   . SER D 4 169 ? 139.313 161.750 193.729 1.00 97.20  ? 170 SER L N   1 
ATOM 4232 C CA  . SER D 4 169 ? 138.234 161.655 192.751 1.00 97.20  ? 170 SER L CA  1 
ATOM 4233 C C   . SER D 4 169 ? 137.643 163.012 192.402 1.00 97.20  ? 170 SER L C   1 
ATOM 4234 O O   . SER D 4 169 ? 136.955 163.131 191.383 1.00 97.20  ? 170 SER L O   1 
ATOM 4235 C CB  . SER D 4 169 ? 137.130 160.739 193.275 1.00 97.20  ? 170 SER L CB  1 
ATOM 4236 O OG  . SER D 4 169 ? 136.568 161.261 194.467 1.00 97.20  ? 170 SER L OG  1 
ATOM 4237 N N   . LYS D 4 170 ? 137.888 164.033 193.220 1.00 100.68 ? 171 LYS L N   1 
ATOM 4238 C CA  . LYS D 4 170 ? 137.342 165.364 193.000 1.00 100.68 ? 171 LYS L CA  1 
ATOM 4239 C C   . LYS D 4 170 ? 138.414 166.405 192.711 1.00 100.68 ? 171 LYS L C   1 
ATOM 4240 O O   . LYS D 4 170 ? 138.316 167.134 191.719 1.00 100.68 ? 171 LYS L O   1 
ATOM 4241 C CB  . LYS D 4 170 ? 136.515 165.788 194.222 1.00 100.68 ? 171 LYS L CB  1 
ATOM 4242 C CG  . LYS D 4 170 ? 135.690 167.043 194.010 1.00 100.68 ? 171 LYS L CG  1 
ATOM 4243 C CD  . LYS D 4 170 ? 134.783 167.317 195.202 1.00 100.68 ? 171 LYS L CD  1 
ATOM 4244 C CE  . LYS D 4 170 ? 135.585 167.617 196.459 1.00 100.68 ? 171 LYS L CE  1 
ATOM 4245 N NZ  . LYS D 4 170 ? 136.327 168.903 196.350 1.00 100.68 ? 171 LYS L NZ  1 
ATOM 4246 N N   . ASP D 4 171 ? 139.442 166.497 193.553 1.00 94.71  ? 172 ASP L N   1 
ATOM 4247 C CA  . ASP D 4 171 ? 140.468 167.519 193.408 1.00 94.71  ? 172 ASP L CA  1 
ATOM 4248 C C   . ASP D 4 171 ? 141.698 167.042 192.650 1.00 94.71  ? 172 ASP L C   1 
ATOM 4249 O O   . ASP D 4 171 ? 142.574 167.860 192.357 1.00 94.71  ? 172 ASP L O   1 
ATOM 4250 C CB  . ASP D 4 171 ? 140.901 168.033 194.785 1.00 94.71  ? 172 ASP L CB  1 
ATOM 4251 C CG  . ASP D 4 171 ? 139.753 168.637 195.571 1.00 94.71  ? 172 ASP L CG  1 
ATOM 4252 O OD1 . ASP D 4 171 ? 138.846 169.230 194.949 1.00 94.71  ? 172 ASP L OD1 1 
ATOM 4253 O OD2 . ASP D 4 171 ? 139.762 168.522 196.814 1.00 94.71  ? 172 ASP L OD2 1 
ATOM 4254 N N   . SER D 4 172 ? 141.784 165.748 192.337 1.00 86.78  ? 173 SER L N   1 
ATOM 4255 C CA  . SER D 4 172 ? 142.909 165.173 191.592 1.00 86.78  ? 173 SER L CA  1 
ATOM 4256 C C   . SER D 4 172 ? 144.246 165.457 192.273 1.00 86.78  ? 173 SER L C   1 
ATOM 4257 O O   . SER D 4 172 ? 145.265 165.675 191.617 1.00 86.78  ? 173 SER L O   1 
ATOM 4258 C CB  . SER D 4 172 ? 142.921 165.668 190.146 1.00 86.78  ? 173 SER L CB  1 
ATOM 4259 O OG  . SER D 4 172 ? 141.689 165.391 189.507 1.00 86.78  ? 173 SER L OG  1 
ATOM 4260 N N   . THR D 4 173 ? 144.246 165.432 193.597 1.00 81.02  ? 174 THR L N   1 
ATOM 4261 C CA  . THR D 4 173 ? 145.442 165.677 194.387 1.00 81.02  ? 174 THR L CA  1 
ATOM 4262 C C   . THR D 4 173 ? 145.856 164.407 195.122 1.00 81.02  ? 174 THR L C   1 
ATOM 4263 O O   . THR D 4 173 ? 145.113 163.425 195.194 1.00 81.02  ? 174 THR L O   1 
ATOM 4264 C CB  . THR D 4 173 ? 145.211 166.822 195.379 1.00 81.02  ? 174 THR L CB  1 
ATOM 4265 O OG1 . THR D 4 173 ? 144.101 166.504 196.225 1.00 81.02  ? 174 THR L OG1 1 
ATOM 4266 C CG2 . THR D 4 173 ? 144.915 168.115 194.644 1.00 81.02  ? 174 THR L CG2 1 
ATOM 4267 N N   . TYR D 4 174 ? 147.061 164.439 195.676 1.00 74.55  ? 175 TYR L N   1 
ATOM 4268 C CA  . TYR D 4 174 ? 147.653 163.305 196.365 1.00 74.55  ? 175 TYR L CA  1 
ATOM 4269 C C   . TYR D 4 174 ? 148.061 163.703 197.775 1.00 74.55  ? 175 TYR L C   1 
ATOM 4270 O O   . TYR D 4 174 ? 148.511 164.827 198.011 1.00 74.55  ? 175 TYR L O   1 
ATOM 4271 C CB  . TYR D 4 174 ? 148.881 162.760 195.620 1.00 74.55  ? 175 TYR L CB  1 
ATOM 4272 C CG  . TYR D 4 174 ? 148.620 162.280 194.206 1.00 74.55  ? 175 TYR L CG  1 
ATOM 4273 C CD1 . TYR D 4 174 ? 148.174 160.991 193.956 1.00 74.55  ? 175 TYR L CD1 1 
ATOM 4274 C CD2 . TYR D 4 174 ? 148.839 163.116 193.121 1.00 74.55  ? 175 TYR L CD2 1 
ATOM 4275 C CE1 . TYR D 4 174 ? 147.949 160.554 192.667 1.00 74.55  ? 175 TYR L CE1 1 
ATOM 4276 C CE2 . TYR D 4 174 ? 148.614 162.686 191.830 1.00 74.55  ? 175 TYR L CE2 1 
ATOM 4277 C CZ  . TYR D 4 174 ? 148.168 161.409 191.608 1.00 74.55  ? 175 TYR L CZ  1 
ATOM 4278 O OH  . TYR D 4 174 ? 147.944 160.991 190.318 1.00 74.55  ? 175 TYR L OH  1 
ATOM 4279 N N   . SER D 4 175 ? 147.915 162.767 198.706 1.00 82.33  ? 176 SER L N   1 
ATOM 4280 C CA  . SER D 4 175 ? 148.354 162.938 200.081 1.00 82.33  ? 176 SER L CA  1 
ATOM 4281 C C   . SER D 4 175 ? 149.417 161.899 200.412 1.00 82.33  ? 176 SER L C   1 
ATOM 4282 O O   . SER D 4 175 ? 149.407 160.787 199.879 1.00 82.33  ? 176 SER L O   1 
ATOM 4283 C CB  . SER D 4 175 ? 147.185 162.817 201.067 1.00 82.33  ? 176 SER L CB  1 
ATOM 4284 O OG  . SER D 4 175 ? 146.190 163.793 200.822 1.00 82.33  ? 176 SER L OG  1 
ATOM 4285 N N   . LEU D 4 176 ? 150.335 162.266 201.298 1.00 88.45  ? 177 LEU L N   1 
ATOM 4286 C CA  . LEU D 4 176 ? 151.434 161.391 201.680 1.00 88.45  ? 177 LEU L CA  1 
ATOM 4287 C C   . LEU D 4 176 ? 151.569 161.384 203.195 1.00 88.45  ? 177 LEU L C   1 
ATOM 4288 O O   . LEU D 4 176 ? 151.611 162.447 203.819 1.00 88.45  ? 177 LEU L O   1 
ATOM 4289 C CB  . LEU D 4 176 ? 152.745 161.841 201.025 1.00 88.45  ? 177 LEU L CB  1 
ATOM 4290 C CG  . LEU D 4 176 ? 154.002 160.992 201.223 1.00 88.45  ? 177 LEU L CG  1 
ATOM 4291 C CD1 . LEU D 4 176 ? 154.894 161.074 199.998 1.00 88.45  ? 177 LEU L CD1 1 
ATOM 4292 C CD2 . LEU D 4 176 ? 154.772 161.430 202.452 1.00 88.45  ? 177 LEU L CD2 1 
ATOM 4293 N N   . SER D 4 177 ? 151.641 160.195 203.784 1.00 96.74  ? 178 SER L N   1 
ATOM 4294 C CA  . SER D 4 177 ? 151.882 160.048 205.211 1.00 96.74  ? 178 SER L CA  1 
ATOM 4295 C C   . SER D 4 177 ? 153.175 159.281 205.410 1.00 96.74  ? 178 SER L C   1 
ATOM 4296 O O   . SER D 4 177 ? 153.350 158.197 204.849 1.00 96.74  ? 178 SER L O   1 
ATOM 4297 C CB  . SER D 4 177 ? 150.729 159.327 205.906 1.00 96.74  ? 178 SER L CB  1 
ATOM 4298 O OG  . SER D 4 177 ? 150.950 159.261 207.302 1.00 96.74  ? 178 SER L OG  1 
ATOM 4299 N N   . SER D 4 178 ? 154.071 159.830 206.217 1.00 105.31 ? 179 SER L N   1 
ATOM 4300 C CA  . SER D 4 178 ? 155.335 159.180 206.527 1.00 105.31 ? 179 SER L CA  1 
ATOM 4301 C C   . SER D 4 178 ? 155.396 158.973 208.028 1.00 105.31 ? 179 SER L C   1 
ATOM 4302 O O   . SER D 4 178 ? 155.263 159.933 208.792 1.00 105.31 ? 179 SER L O   1 
ATOM 4303 C CB  . SER D 4 178 ? 156.521 160.013 206.044 1.00 105.31 ? 179 SER L CB  1 
ATOM 4304 O OG  . SER D 4 178 ? 157.744 159.335 206.266 1.00 105.31 ? 179 SER L OG  1 
ATOM 4305 N N   . THR D 4 179 ? 155.582 157.729 208.453 1.00 113.97 ? 180 THR L N   1 
ATOM 4306 C CA  . THR D 4 179 ? 155.620 157.392 209.866 1.00 113.97 ? 180 THR L CA  1 
ATOM 4307 C C   . THR D 4 179 ? 157.034 156.989 210.247 1.00 113.97 ? 180 THR L C   1 
ATOM 4308 O O   . THR D 4 179 ? 157.634 156.128 209.595 1.00 113.97 ? 180 THR L O   1 
ATOM 4309 C CB  . THR D 4 179 ? 154.640 156.269 210.196 1.00 113.97 ? 180 THR L CB  1 
ATOM 4310 O OG1 . THR D 4 179 ? 153.318 156.659 209.809 1.00 113.97 ? 180 THR L OG1 1 
ATOM 4311 C CG2 . THR D 4 179 ? 154.654 155.987 211.683 1.00 113.97 ? 180 THR L CG2 1 
ATOM 4312 N N   . LEU D 4 180 ? 157.556 157.629 211.286 1.00 124.28 ? 181 LEU L N   1 
ATOM 4313 C CA  . LEU D 4 180 ? 158.859 157.328 211.860 1.00 124.28 ? 181 LEU L CA  1 
ATOM 4314 C C   . LEU D 4 180 ? 158.622 156.577 213.162 1.00 124.28 ? 181 LEU L C   1 
ATOM 4315 O O   . LEU D 4 180 ? 157.940 157.088 214.056 1.00 124.28 ? 181 LEU L O   1 
ATOM 4316 C CB  . LEU D 4 180 ? 159.646 158.610 212.117 1.00 124.28 ? 181 LEU L CB  1 
ATOM 4317 C CG  . LEU D 4 180 ? 160.954 158.484 212.891 1.00 124.28 ? 181 LEU L CG  1 
ATOM 4318 C CD1 . LEU D 4 180 ? 162.040 157.943 211.991 1.00 124.28 ? 181 LEU L CD1 1 
ATOM 4319 C CD2 . LEU D 4 180 ? 161.362 159.823 213.478 1.00 124.28 ? 181 LEU L CD2 1 
ATOM 4320 N N   . THR D 4 181 ? 159.176 155.374 213.271 1.00 135.62 ? 182 THR L N   1 
ATOM 4321 C CA  . THR D 4 181 ? 158.881 154.478 214.382 1.00 135.62 ? 182 THR L CA  1 
ATOM 4322 C C   . THR D 4 181 ? 160.135 154.274 215.219 1.00 135.62 ? 182 THR L C   1 
ATOM 4323 O O   . THR D 4 181 ? 161.152 153.795 214.709 1.00 135.62 ? 182 THR L O   1 
ATOM 4324 C CB  . THR D 4 181 ? 158.351 153.138 213.877 1.00 135.62 ? 182 THR L CB  1 
ATOM 4325 O OG1 . THR D 4 181 ? 157.062 153.325 213.277 1.00 135.62 ? 182 THR L OG1 1 
ATOM 4326 C CG2 . THR D 4 181 ? 158.229 152.157 215.021 1.00 135.62 ? 182 THR L CG2 1 
ATOM 4327 N N   . LEU D 4 182 ? 160.053 154.628 216.499 1.00 141.76 ? 183 LEU L N   1 
ATOM 4328 C CA  . LEU D 4 182 ? 161.138 154.438 217.449 1.00 141.76 ? 183 LEU L CA  1 
ATOM 4329 C C   . LEU D 4 182 ? 160.624 153.680 218.667 1.00 141.76 ? 183 LEU L C   1 
ATOM 4330 O O   . LEU D 4 182 ? 159.417 153.552 218.884 1.00 141.76 ? 183 LEU L O   1 
ATOM 4331 C CB  . LEU D 4 182 ? 161.745 155.781 217.879 1.00 141.76 ? 183 LEU L CB  1 
ATOM 4332 C CG  . LEU D 4 182 ? 162.353 156.629 216.759 1.00 141.76 ? 183 LEU L CG  1 
ATOM 4333 C CD1 . LEU D 4 182 ? 163.008 157.885 217.315 1.00 141.76 ? 183 LEU L CD1 1 
ATOM 4334 C CD2 . LEU D 4 182 ? 163.354 155.814 215.956 1.00 141.76 ? 183 LEU L CD2 1 
ATOM 4335 N N   . SER D 4 183 ? 161.558 153.156 219.457 1.00 147.23 ? 184 SER L N   1 
ATOM 4336 C CA  . SER D 4 183 ? 161.186 152.581 220.739 1.00 147.23 ? 184 SER L CA  1 
ATOM 4337 C C   . SER D 4 183 ? 160.850 153.697 221.725 1.00 147.23 ? 184 SER L C   1 
ATOM 4338 O O   . SER D 4 183 ? 161.106 154.877 221.477 1.00 147.23 ? 184 SER L O   1 
ATOM 4339 C CB  . SER D 4 183 ? 162.311 151.705 221.288 1.00 147.23 ? 184 SER L CB  1 
ATOM 4340 O OG  . SER D 4 183 ? 163.323 152.490 221.893 1.00 147.23 ? 184 SER L OG  1 
ATOM 4341 N N   . LYS D 4 184 ? 160.248 153.316 222.853 1.00 148.28 ? 185 LYS L N   1 
ATOM 4342 C CA  . LYS D 4 184 ? 159.972 154.294 223.901 1.00 148.28 ? 185 LYS L CA  1 
ATOM 4343 C C   . LYS D 4 184 ? 161.261 154.947 224.386 1.00 148.28 ? 185 LYS L C   1 
ATOM 4344 O O   . LYS D 4 184 ? 161.341 156.176 224.524 1.00 148.28 ? 185 LYS L O   1 
ATOM 4345 C CB  . LYS D 4 184 ? 159.241 153.624 225.064 1.00 148.28 ? 185 LYS L CB  1 
ATOM 4346 C CG  . LYS D 4 184 ? 158.757 154.596 226.122 1.00 148.28 ? 185 LYS L CG  1 
ATOM 4347 C CD  . LYS D 4 184 ? 157.969 153.881 227.200 1.00 148.28 ? 185 LYS L CD  1 
ATOM 4348 C CE  . LYS D 4 184 ? 157.253 154.869 228.098 1.00 148.28 ? 185 LYS L CE  1 
ATOM 4349 N NZ  . LYS D 4 184 ? 158.211 155.741 228.824 1.00 148.28 ? 185 LYS L NZ  1 
ATOM 4350 N N   . ALA D 4 185 ? 162.286 154.134 224.640 1.00 151.59 ? 186 ALA L N   1 
ATOM 4351 C CA  . ALA D 4 185 ? 163.566 154.672 225.081 1.00 151.59 ? 186 ALA L CA  1 
ATOM 4352 C C   . ALA D 4 185 ? 164.184 155.553 224.008 1.00 151.59 ? 186 ALA L C   1 
ATOM 4353 O O   . ALA D 4 185 ? 164.752 156.608 224.311 1.00 151.59 ? 186 ALA L O   1 
ATOM 4354 C CB  . ALA D 4 185 ? 164.510 153.532 225.460 1.00 151.59 ? 186 ALA L CB  1 
ATOM 4355 N N   . ASP D 4 186 ? 164.066 155.147 222.744 1.00 151.29 ? 187 ASP L N   1 
ATOM 4356 C CA  . ASP D 4 186 ? 164.615 155.950 221.656 1.00 151.29 ? 187 ASP L CA  1 
ATOM 4357 C C   . ASP D 4 186 ? 163.898 157.285 221.534 1.00 151.29 ? 187 ASP L C   1 
ATOM 4358 O O   . ASP D 4 186 ? 164.532 158.306 221.247 1.00 151.29 ? 187 ASP L O   1 
ATOM 4359 C CB  . ASP D 4 186 ? 164.538 155.183 220.340 1.00 151.29 ? 187 ASP L CB  1 
ATOM 4360 C CG  . ASP D 4 186 ? 165.385 153.932 220.348 1.00 151.29 ? 187 ASP L CG  1 
ATOM 4361 O OD1 . ASP D 4 186 ? 166.375 153.891 221.107 1.00 151.29 ? 187 ASP L OD1 1 
ATOM 4362 O OD2 . ASP D 4 186 ? 165.059 152.985 219.602 1.00 151.29 ? 187 ASP L OD2 1 
ATOM 4363 N N   . TYR D 4 187 ? 162.578 157.297 221.735 1.00 148.03 ? 188 TYR L N   1 
ATOM 4364 C CA  . TYR D 4 187 ? 161.842 158.556 221.746 1.00 148.03 ? 188 TYR L CA  1 
ATOM 4365 C C   . TYR D 4 187 ? 162.315 159.449 222.884 1.00 148.03 ? 188 TYR L C   1 
ATOM 4366 O O   . TYR D 4 187 ? 162.540 160.650 222.694 1.00 148.03 ? 188 TYR L O   1 
ATOM 4367 C CB  . TYR D 4 187 ? 160.344 158.283 221.857 1.00 148.03 ? 188 TYR L CB  1 
ATOM 4368 C CG  . TYR D 4 187 ? 159.478 159.513 221.715 1.00 148.03 ? 188 TYR L CG  1 
ATOM 4369 C CD1 . TYR D 4 187 ? 159.436 160.224 220.523 1.00 148.03 ? 188 TYR L CD1 1 
ATOM 4370 C CD2 . TYR D 4 187 ? 158.691 159.957 222.768 1.00 148.03 ? 188 TYR L CD2 1 
ATOM 4371 C CE1 . TYR D 4 187 ? 158.642 161.350 220.387 1.00 148.03 ? 188 TYR L CE1 1 
ATOM 4372 C CE2 . TYR D 4 187 ? 157.889 161.077 222.639 1.00 148.03 ? 188 TYR L CE2 1 
ATOM 4373 C CZ  . TYR D 4 187 ? 157.874 161.773 221.448 1.00 148.03 ? 188 TYR L CZ  1 
ATOM 4374 O OH  . TYR D 4 187 ? 157.083 162.889 221.314 1.00 148.03 ? 188 TYR L OH  1 
ATOM 4375 N N   . GLU D 4 188 ? 162.482 158.878 224.080 1.00 152.84 ? 189 GLU L N   1 
ATOM 4376 C CA  . GLU D 4 188 ? 162.942 159.681 225.208 1.00 152.84 ? 189 GLU L CA  1 
ATOM 4377 C C   . GLU D 4 188 ? 164.377 160.170 225.029 1.00 152.84 ? 189 GLU L C   1 
ATOM 4378 O O   . GLU D 4 188 ? 164.759 161.169 225.646 1.00 152.84 ? 189 GLU L O   1 
ATOM 4379 C CB  . GLU D 4 188 ? 162.813 158.885 226.508 1.00 152.84 ? 189 GLU L CB  1 
ATOM 4380 C CG  . GLU D 4 188 ? 161.375 158.598 226.900 1.00 152.84 ? 189 GLU L CG  1 
ATOM 4381 C CD  . GLU D 4 188 ? 161.268 157.802 228.183 1.00 152.84 ? 189 GLU L CD  1 
ATOM 4382 O OE1 . GLU D 4 188 ? 162.279 157.194 228.593 1.00 152.84 ? 189 GLU L OE1 1 
ATOM 4383 O OE2 . GLU D 4 188 ? 160.173 157.788 228.784 1.00 152.84 ? 189 GLU L OE2 1 
ATOM 4384 N N   . LYS D 4 189 ? 165.178 159.488 224.210 1.00 151.15 ? 190 LYS L N   1 
ATOM 4385 C CA  . LYS D 4 189 ? 166.570 159.898 224.037 1.00 151.15 ? 190 LYS L CA  1 
ATOM 4386 C C   . LYS D 4 189 ? 166.706 161.289 223.427 1.00 151.15 ? 190 LYS L C   1 
ATOM 4387 O O   . LYS D 4 189 ? 167.722 161.955 223.651 1.00 151.15 ? 190 LYS L O   1 
ATOM 4388 C CB  . LYS D 4 189 ? 167.324 158.894 223.166 1.00 151.15 ? 190 LYS L CB  1 
ATOM 4389 C CG  . LYS D 4 189 ? 167.648 157.581 223.849 1.00 151.15 ? 190 LYS L CG  1 
ATOM 4390 C CD  . LYS D 4 189 ? 168.146 156.559 222.842 1.00 151.15 ? 190 LYS L CD  1 
ATOM 4391 C CE  . LYS D 4 189 ? 168.458 155.232 223.513 1.00 151.15 ? 190 LYS L CE  1 
ATOM 4392 N NZ  . LYS D 4 189 ? 169.030 154.244 222.556 1.00 151.15 ? 190 LYS L NZ  1 
ATOM 4393 N N   . HIS D 4 190 ? 165.721 161.744 222.656 1.00 149.98 ? 191 HIS L N   1 
ATOM 4394 C CA  . HIS D 4 190 ? 165.860 162.971 221.881 1.00 149.98 ? 191 HIS L CA  1 
ATOM 4395 C C   . HIS D 4 190 ? 164.799 163.991 222.278 1.00 149.98 ? 191 HIS L C   1 
ATOM 4396 O O   . HIS D 4 190 ? 163.838 163.685 222.987 1.00 149.98 ? 191 HIS L O   1 
ATOM 4397 C CB  . HIS D 4 190 ? 165.778 162.679 220.379 1.00 149.98 ? 191 HIS L CB  1 
ATOM 4398 C CG  . HIS D 4 190 ? 166.828 161.731 219.888 1.00 149.98 ? 191 HIS L CG  1 
ATOM 4399 N ND1 . HIS D 4 190 ? 168.133 162.113 219.665 1.00 149.98 ? 191 HIS L ND1 1 
ATOM 4400 C CD2 . HIS D 4 190 ? 166.762 160.417 219.567 1.00 149.98 ? 191 HIS L CD2 1 
ATOM 4401 C CE1 . HIS D 4 190 ? 168.827 161.075 219.233 1.00 149.98 ? 191 HIS L CE1 1 
ATOM 4402 N NE2 . HIS D 4 190 ? 168.019 160.033 219.166 1.00 149.98 ? 191 HIS L NE2 1 
ATOM 4403 N N   . LYS D 4 191 ? 164.995 165.223 221.804 1.00 147.05 ? 192 LYS L N   1 
ATOM 4404 C CA  . LYS D 4 191 ? 164.143 166.358 222.138 1.00 147.05 ? 192 LYS L CA  1 
ATOM 4405 C C   . LYS D 4 191 ? 163.290 166.838 220.972 1.00 147.05 ? 192 LYS L C   1 
ATOM 4406 O O   . LYS D 4 191 ? 162.065 166.926 221.099 1.00 147.05 ? 192 LYS L O   1 
ATOM 4407 C CB  . LYS D 4 191 ? 165.010 167.517 222.657 1.00 147.05 ? 192 LYS L CB  1 
ATOM 4408 C CG  . LYS D 4 191 ? 164.232 168.768 223.027 1.00 147.05 ? 192 LYS L CG  1 
ATOM 4409 C CD  . LYS D 4 191 ? 165.164 169.875 223.496 1.00 147.05 ? 192 LYS L CD  1 
ATOM 4410 C CE  . LYS D 4 191 ? 164.394 171.157 223.774 1.00 147.05 ? 192 LYS L CE  1 
ATOM 4411 N NZ  . LYS D 4 191 ? 165.271 172.259 224.263 1.00 147.05 ? 192 LYS L NZ  1 
ATOM 4412 N N   . VAL D 4 192 ? 163.900 167.142 219.828 1.00 142.17 ? 193 VAL L N   1 
ATOM 4413 C CA  . VAL D 4 192 ? 163.236 167.843 218.732 1.00 142.17 ? 193 VAL L CA  1 
ATOM 4414 C C   . VAL D 4 192 ? 163.017 166.875 217.578 1.00 142.17 ? 193 VAL L C   1 
ATOM 4415 O O   . VAL D 4 192 ? 163.965 166.234 217.109 1.00 142.17 ? 193 VAL L O   1 
ATOM 4416 C CB  . VAL D 4 192 ? 164.059 169.059 218.274 1.00 142.17 ? 193 VAL L CB  1 
ATOM 4417 C CG1 . VAL D 4 192 ? 163.367 169.767 217.125 1.00 142.17 ? 193 VAL L CG1 1 
ATOM 4418 C CG2 . VAL D 4 192 ? 164.292 170.014 219.434 1.00 142.17 ? 193 VAL L CG2 1 
ATOM 4419 N N   . TYR D 4 193 ? 161.774 166.781 217.110 1.00 138.42 ? 194 TYR L N   1 
ATOM 4420 C CA  . TYR D 4 193 ? 161.431 165.955 215.960 1.00 138.42 ? 194 TYR L CA  1 
ATOM 4421 C C   . TYR D 4 193 ? 160.945 166.841 214.822 1.00 138.42 ? 194 TYR L C   1 
ATOM 4422 O O   . TYR D 4 193 ? 160.169 167.774 215.042 1.00 138.42 ? 194 TYR L O   1 
ATOM 4423 C CB  . TYR D 4 193 ? 160.368 164.918 216.331 1.00 138.42 ? 194 TYR L CB  1 
ATOM 4424 C CG  . TYR D 4 193 ? 160.908 163.867 217.271 1.00 138.42 ? 194 TYR L CG  1 
ATOM 4425 C CD1 . TYR D 4 193 ? 161.031 164.125 218.628 1.00 138.42 ? 194 TYR L CD1 1 
ATOM 4426 C CD2 . TYR D 4 193 ? 161.324 162.628 216.799 1.00 138.42 ? 194 TYR L CD2 1 
ATOM 4427 C CE1 . TYR D 4 193 ? 161.540 163.180 219.489 1.00 138.42 ? 194 TYR L CE1 1 
ATOM 4428 C CE2 . TYR D 4 193 ? 161.833 161.675 217.657 1.00 138.42 ? 194 TYR L CE2 1 
ATOM 4429 C CZ  . TYR D 4 193 ? 161.938 161.958 219.000 1.00 138.42 ? 194 TYR L CZ  1 
ATOM 4430 O OH  . TYR D 4 193 ? 162.444 161.014 219.857 1.00 138.42 ? 194 TYR L OH  1 
ATOM 4431 N N   . ALA D 4 194 ? 161.399 166.552 213.601 1.00 123.81 ? 195 ALA L N   1 
ATOM 4432 C CA  . ALA D 4 194 ? 161.132 167.440 212.481 1.00 123.81 ? 195 ALA L CA  1 
ATOM 4433 C C   . ALA D 4 194 ? 160.936 166.640 211.202 1.00 123.81 ? 195 ALA L C   1 
ATOM 4434 O O   . ALA D 4 194 ? 161.525 165.573 211.014 1.00 123.81 ? 195 ALA L O   1 
ATOM 4435 C CB  . ALA D 4 194 ? 162.268 168.450 212.292 1.00 123.81 ? 195 ALA L CB  1 
ATOM 4436 N N   . CYS D 4 195 ? 160.111 167.189 210.319 1.00 116.92 ? 196 CYS L N   1 
ATOM 4437 C CA  . CYS D 4 195 ? 159.842 166.641 208.999 1.00 116.92 ? 196 CYS L CA  1 
ATOM 4438 C C   . CYS D 4 195 ? 160.150 167.719 207.969 1.00 116.92 ? 196 CYS L C   1 
ATOM 4439 O O   . CYS D 4 195 ? 159.590 168.822 208.032 1.00 116.92 ? 196 CYS L O   1 
ATOM 4440 C CB  . CYS D 4 195 ? 158.387 166.177 208.899 1.00 116.92 ? 196 CYS L CB  1 
ATOM 4441 S SG  . CYS D 4 195 ? 157.864 165.625 207.275 1.00 116.92 ? 196 CYS L SG  1 
ATOM 4442 N N   . GLU D 4 196 ? 161.058 167.413 207.044 1.00 109.44 ? 197 GLU L N   1 
ATOM 4443 C CA  . GLU D 4 196 ? 161.394 168.299 205.939 1.00 109.44 ? 197 GLU L CA  1 
ATOM 4444 C C   . GLU D 4 196 ? 160.761 167.765 204.661 1.00 109.44 ? 197 GLU L C   1 
ATOM 4445 O O   . GLU D 4 196 ? 160.895 166.583 204.340 1.00 109.44 ? 197 GLU L O   1 
ATOM 4446 C CB  . GLU D 4 196 ? 162.908 168.413 205.781 1.00 109.44 ? 197 GLU L CB  1 
ATOM 4447 C CG  . GLU D 4 196 ? 163.351 169.287 204.634 1.00 109.44 ? 197 GLU L CG  1 
ATOM 4448 C CD  . GLU D 4 196 ? 164.856 169.421 204.568 1.00 109.44 ? 197 GLU L CD  1 
ATOM 4449 O OE1 . GLU D 4 196 ? 165.549 168.709 205.321 1.00 109.44 ? 197 GLU L OE1 1 
ATOM 4450 O OE2 . GLU D 4 196 ? 165.351 170.238 203.767 1.00 109.44 ? 197 GLU L OE2 1 
ATOM 4451 N N   . VAL D 4 197 ? 160.072 168.634 203.939 1.00 96.80  ? 198 VAL L N   1 
ATOM 4452 C CA  . VAL D 4 197 ? 159.271 168.253 202.787 1.00 96.80  ? 198 VAL L CA  1 
ATOM 4453 C C   . VAL D 4 197 ? 159.731 169.064 201.589 1.00 96.80  ? 198 VAL L C   1 
ATOM 4454 O O   . VAL D 4 197 ? 159.929 170.282 201.693 1.00 96.80  ? 198 VAL L O   1 
ATOM 4455 C CB  . VAL D 4 197 ? 157.775 168.465 203.057 1.00 96.80  ? 198 VAL L CB  1 
ATOM 4456 C CG1 . VAL D 4 197 ? 156.955 168.118 201.831 1.00 96.80  ? 198 VAL L CG1 1 
ATOM 4457 C CG2 . VAL D 4 197 ? 157.363 167.636 204.250 1.00 96.80  ? 198 VAL L CG2 1 
ATOM 4458 N N   . THR D 4 198 ? 159.911 168.380 200.461 1.00 92.35  ? 199 THR L N   1 
ATOM 4459 C CA  . THR D 4 198 ? 160.373 168.980 199.219 1.00 92.35  ? 199 THR L CA  1 
ATOM 4460 C C   . THR D 4 198 ? 159.453 168.555 198.087 1.00 92.35  ? 199 THR L C   1 
ATOM 4461 O O   . THR D 4 198 ? 159.115 167.374 197.966 1.00 92.35  ? 199 THR L O   1 
ATOM 4462 C CB  . THR D 4 198 ? 161.815 168.566 198.920 1.00 92.35  ? 199 THR L CB  1 
ATOM 4463 O OG1 . THR D 4 198 ? 162.669 169.019 199.976 1.00 92.35  ? 199 THR L OG1 1 
ATOM 4464 C CG2 . THR D 4 198 ? 162.279 169.167 197.626 1.00 92.35  ? 199 THR L CG2 1 
ATOM 4465 N N   . HIS D 4 199 ? 159.046 169.518 197.267 1.00 80.90  ? 200 HIS L N   1 
ATOM 4466 C CA  . HIS D 4 199 ? 158.213 169.249 196.108 1.00 80.90  ? 200 HIS L CA  1 
ATOM 4467 C C   . HIS D 4 199 ? 158.533 170.286 195.047 1.00 80.90  ? 200 HIS L C   1 
ATOM 4468 O O   . HIS D 4 199 ? 159.105 171.338 195.337 1.00 80.90  ? 200 HIS L O   1 
ATOM 4469 C CB  . HIS D 4 199 ? 156.723 169.257 196.460 1.00 80.90  ? 200 HIS L CB  1 
ATOM 4470 C CG  . HIS D 4 199 ? 156.339 170.313 197.450 1.00 80.90  ? 200 HIS L CG  1 
ATOM 4471 N ND1 . HIS D 4 199 ? 156.474 170.141 198.811 1.00 80.90  ? 200 HIS L ND1 1 
ATOM 4472 C CD2 . HIS D 4 199 ? 155.814 171.549 197.278 1.00 80.90  ? 200 HIS L CD2 1 
ATOM 4473 C CE1 . HIS D 4 199 ? 156.055 171.227 199.434 1.00 80.90  ? 200 HIS L CE1 1 
ATOM 4474 N NE2 . HIS D 4 199 ? 155.654 172.099 198.527 1.00 80.90  ? 200 HIS L NE2 1 
ATOM 4475 N N   . GLN D 4 200 ? 158.178 169.966 193.802 1.00 87.81  ? 201 GLN L N   1 
ATOM 4476 C CA  . GLN D 4 200 ? 158.490 170.866 192.699 1.00 87.81  ? 201 GLN L CA  1 
ATOM 4477 C C   . GLN D 4 200 ? 157.745 172.187 192.797 1.00 87.81  ? 201 GLN L C   1 
ATOM 4478 O O   . GLN D 4 200 ? 158.196 173.179 192.219 1.00 87.81  ? 201 GLN L O   1 
ATOM 4479 C CB  . GLN D 4 200 ? 158.187 170.192 191.362 1.00 87.81  ? 201 GLN L CB  1 
ATOM 4480 C CG  . GLN D 4 200 ? 159.184 169.110 190.977 1.00 87.81  ? 201 GLN L CG  1 
ATOM 4481 C CD  . GLN D 4 200 ? 159.107 168.746 189.509 1.00 87.81  ? 201 GLN L CD  1 
ATOM 4482 O OE1 . GLN D 4 200 ? 158.040 168.801 188.901 1.00 87.81  ? 201 GLN L OE1 1 
ATOM 4483 N NE2 . GLN D 4 200 ? 160.243 168.390 188.927 1.00 87.81  ? 201 GLN L NE2 1 
ATOM 4484 N N   . GLY D 4 201 ? 156.624 172.227 193.508 1.00 81.48  ? 202 GLY L N   1 
ATOM 4485 C CA  . GLY D 4 201 ? 155.919 173.463 193.761 1.00 81.48  ? 202 GLY L CA  1 
ATOM 4486 C C   . GLY D 4 201 ? 156.454 174.272 194.917 1.00 81.48  ? 202 GLY L C   1 
ATOM 4487 O O   . GLY D 4 201 ? 155.826 175.250 195.325 1.00 81.48  ? 202 GLY L O   1 
ATOM 4488 N N   . LEU D 4 202 ? 157.596 173.882 195.465 1.00 87.31  ? 203 LEU L N   1 
ATOM 4489 C CA  . LEU D 4 202 ? 158.173 174.521 196.635 1.00 87.31  ? 203 LEU L CA  1 
ATOM 4490 C C   . LEU D 4 202 ? 159.458 175.234 196.246 1.00 87.31  ? 203 LEU L C   1 
ATOM 4491 O O   . LEU D 4 202 ? 160.348 174.629 195.642 1.00 87.31  ? 203 LEU L O   1 
ATOM 4492 C CB  . LEU D 4 202 ? 158.455 173.486 197.725 1.00 87.31  ? 203 LEU L CB  1 
ATOM 4493 C CG  . LEU D 4 202 ? 158.625 174.009 199.145 1.00 87.31  ? 203 LEU L CG  1 
ATOM 4494 C CD1 . LEU D 4 202 ? 157.367 174.731 199.586 1.00 87.31  ? 203 LEU L CD1 1 
ATOM 4495 C CD2 . LEU D 4 202 ? 158.960 172.873 200.093 1.00 87.31  ? 203 LEU L CD2 1 
ATOM 4496 N N   . SER D 4 203 ? 159.554 176.515 196.593 1.00 99.52  ? 204 SER L N   1 
ATOM 4497 C CA  . SER D 4 203 ? 160.782 177.259 196.353 1.00 99.52  ? 204 SER L CA  1 
ATOM 4498 C C   . SER D 4 203 ? 161.828 177.051 197.439 1.00 99.52  ? 204 SER L C   1 
ATOM 4499 O O   . SER D 4 203 ? 162.995 177.383 197.220 1.00 99.52  ? 204 SER L O   1 
ATOM 4500 C CB  . SER D 4 203 ? 160.475 178.753 196.220 1.00 99.52  ? 204 SER L CB  1 
ATOM 4501 O OG  . SER D 4 203 ? 159.906 179.268 197.414 1.00 99.52  ? 204 SER L OG  1 
ATOM 4502 N N   . SER D 4 204 ? 161.445 176.508 198.598 1.00 103.19 ? 205 SER L N   1 
ATOM 4503 C CA  . SER D 4 204 ? 162.379 176.345 199.704 1.00 103.19 ? 205 SER L CA  1 
ATOM 4504 C C   . SER D 4 204 ? 161.824 175.300 200.649 1.00 103.19 ? 205 SER L C   1 
ATOM 4505 O O   . SER D 4 204 ? 160.636 175.375 200.995 1.00 103.19 ? 205 SER L O   1 
ATOM 4506 C CB  . SER D 4 204 ? 162.598 177.669 200.442 1.00 103.19 ? 205 SER L CB  1 
ATOM 4507 O OG  . SER D 4 204 ? 163.570 177.538 201.463 1.00 103.19 ? 205 SER L OG  1 
ATOM 4508 N N   . PRO D 4 205 ? 162.638 174.355 201.124 1.00 103.54 ? 206 PRO L N   1 
ATOM 4509 C CA  . PRO D 4 205 ? 162.098 173.179 201.822 1.00 103.54 ? 206 PRO L CA  1 
ATOM 4510 C C   . PRO D 4 205 ? 161.239 173.558 203.023 1.00 103.54 ? 206 PRO L C   1 
ATOM 4511 O O   . PRO D 4 205 ? 161.552 174.486 203.768 1.00 103.54 ? 206 PRO L O   1 
ATOM 4512 C CB  . PRO D 4 205 ? 163.356 172.418 202.255 1.00 103.54 ? 206 PRO L CB  1 
ATOM 4513 C CG  . PRO D 4 205 ? 164.432 172.895 201.336 1.00 103.54 ? 206 PRO L CG  1 
ATOM 4514 C CD  . PRO D 4 205 ? 164.107 174.319 201.022 1.00 103.54 ? 206 PRO L CD  1 
ATOM 4515 N N   . VAL D 4 206 ? 160.145 172.819 203.203 1.00 103.06 ? 207 VAL L N   1 
ATOM 4516 C CA  . VAL D 4 206 ? 159.207 173.072 204.293 1.00 103.06 ? 207 VAL L CA  1 
ATOM 4517 C C   . VAL D 4 206 ? 159.638 172.253 205.496 1.00 103.06 ? 207 VAL L C   1 
ATOM 4518 O O   . VAL D 4 206 ? 159.855 171.044 205.384 1.00 103.06 ? 207 VAL L O   1 
ATOM 4519 C CB  . VAL D 4 206 ? 157.769 172.715 203.881 1.00 103.06 ? 207 VAL L CB  1 
ATOM 4520 C CG1 . VAL D 4 206 ? 156.941 172.395 205.110 1.00 103.06 ? 207 VAL L CG1 1 
ATOM 4521 C CG2 . VAL D 4 206 ? 157.137 173.852 203.107 1.00 103.06 ? 207 VAL L CG2 1 
ATOM 4522 N N   . THR D 4 207 ? 159.764 172.894 206.650 1.00 111.46 ? 208 THR L N   1 
ATOM 4523 C CA  . THR D 4 207 ? 160.156 172.193 207.866 1.00 111.46 ? 208 THR L CA  1 
ATOM 4524 C C   . THR D 4 207 ? 159.065 172.357 208.909 1.00 111.46 ? 208 THR L C   1 
ATOM 4525 O O   . THR D 4 207 ? 158.721 173.483 209.281 1.00 111.46 ? 208 THR L O   1 
ATOM 4526 C CB  . THR D 4 207 ? 161.493 172.705 208.403 1.00 111.46 ? 208 THR L CB  1 
ATOM 4527 O OG1 . THR D 4 207 ? 162.539 172.390 207.477 1.00 111.46 ? 208 THR L OG1 1 
ATOM 4528 C CG2 . THR D 4 207 ? 161.809 172.068 209.746 1.00 111.46 ? 208 THR L CG2 1 
ATOM 4529 N N   . LYS D 4 208 ? 158.525 171.239 209.375 1.00 112.81 ? 209 LYS L N   1 
ATOM 4530 C CA  . LYS D 4 208 ? 157.639 171.224 210.527 1.00 112.81 ? 209 LYS L CA  1 
ATOM 4531 C C   . LYS D 4 208 ? 158.358 170.513 211.663 1.00 112.81 ? 209 LYS L C   1 
ATOM 4532 O O   . LYS D 4 208 ? 159.183 169.633 211.427 1.00 112.81 ? 209 LYS L O   1 
ATOM 4533 C CB  . LYS D 4 208 ? 156.314 170.530 210.206 1.00 112.81 ? 209 LYS L CB  1 
ATOM 4534 C CG  . LYS D 4 208 ? 155.460 171.270 209.191 1.00 112.81 ? 209 LYS L CG  1 
ATOM 4535 C CD  . LYS D 4 208 ? 155.228 172.714 209.614 1.00 112.81 ? 209 LYS L CD  1 
ATOM 4536 C CE  . LYS D 4 208 ? 154.337 173.459 208.629 1.00 112.81 ? 209 LYS L CE  1 
ATOM 4537 N NZ  . LYS D 4 208 ? 154.119 174.874 209.042 1.00 112.81 ? 209 LYS L NZ  1 
ATOM 4538 N N   . SER D 4 209 ? 158.078 170.914 212.899 1.00 125.34 ? 210 SER L N   1 
ATOM 4539 C CA  . SER D 4 209 ? 158.815 170.327 214.007 1.00 125.34 ? 210 SER L CA  1 
ATOM 4540 C C   . SER D 4 209 ? 158.032 170.497 215.299 1.00 125.34 ? 210 SER L C   1 
ATOM 4541 O O   . SER D 4 209 ? 157.106 171.306 215.390 1.00 125.34 ? 210 SER L O   1 
ATOM 4542 C CB  . SER D 4 209 ? 160.214 170.942 214.138 1.00 125.34 ? 210 SER L CB  1 
ATOM 4543 O OG  . SER D 4 209 ? 160.147 172.301 214.530 1.00 125.34 ? 210 SER L OG  1 
ATOM 4544 N N   . PHE D 4 210 ? 158.424 169.709 216.298 1.00 135.70 ? 211 PHE L N   1 
ATOM 4545 C CA  . PHE D 4 210 ? 157.844 169.800 217.629 1.00 135.70 ? 211 PHE L CA  1 
ATOM 4546 C C   . PHE D 4 210 ? 158.863 169.339 218.660 1.00 135.70 ? 211 PHE L C   1 
ATOM 4547 O O   . PHE D 4 210 ? 159.868 168.695 218.337 1.00 135.70 ? 211 PHE L O   1 
ATOM 4548 C CB  . PHE D 4 210 ? 156.550 168.982 217.754 1.00 135.70 ? 211 PHE L CB  1 
ATOM 4549 C CG  . PHE D 4 210 ? 156.762 167.496 217.765 1.00 135.70 ? 211 PHE L CG  1 
ATOM 4550 C CD1 . PHE D 4 210 ? 157.056 166.825 218.945 1.00 135.70 ? 211 PHE L CD1 1 
ATOM 4551 C CD2 . PHE D 4 210 ? 156.645 166.764 216.600 1.00 135.70 ? 211 PHE L CD2 1 
ATOM 4552 C CE1 . PHE D 4 210 ? 157.251 165.462 218.952 1.00 135.70 ? 211 PHE L CE1 1 
ATOM 4553 C CE2 . PHE D 4 210 ? 156.830 165.402 216.603 1.00 135.70 ? 211 PHE L CE2 1 
ATOM 4554 C CZ  . PHE D 4 210 ? 157.136 164.748 217.778 1.00 135.70 ? 211 PHE L CZ  1 
ATOM 4555 N N   . ASN D 4 211 ? 158.587 169.691 219.913 1.00 145.43 ? 212 ASN L N   1 
ATOM 4556 C CA  . ASN D 4 211 ? 159.346 169.214 221.059 1.00 145.43 ? 212 ASN L CA  1 
ATOM 4557 C C   . ASN D 4 211 ? 158.633 168.018 221.674 1.00 145.43 ? 212 ASN L C   1 
ATOM 4558 O O   . ASN D 4 211 ? 157.408 168.028 221.829 1.00 145.43 ? 212 ASN L O   1 
ATOM 4559 C CB  . ASN D 4 211 ? 159.510 170.313 222.112 1.00 145.43 ? 212 ASN L CB  1 
ATOM 4560 C CG  . ASN D 4 211 ? 160.240 171.531 221.583 1.00 145.43 ? 212 ASN L CG  1 
ATOM 4561 O OD1 . ASN D 4 211 ? 161.202 171.418 220.823 1.00 145.43 ? 212 ASN L OD1 1 
ATOM 4562 N ND2 . ASN D 4 211 ? 159.787 172.710 221.993 1.00 145.43 ? 212 ASN L ND2 1 
ATOM 4563 N N   . ARG D 4 212 ? 159.407 166.988 222.012 1.00 148.52 ? 213 ARG L N   1 
ATOM 4564 C CA  . ARG D 4 212 ? 158.898 165.770 222.640 1.00 148.52 ? 213 ARG L CA  1 
ATOM 4565 C C   . ARG D 4 212 ? 157.946 166.057 223.796 1.00 148.52 ? 213 ARG L C   1 
ATOM 4566 O O   . ARG D 4 212 ? 156.794 165.626 223.780 1.00 148.52 ? 213 ARG L O   1 
ATOM 4567 C CB  . ARG D 4 212 ? 160.065 164.915 223.136 1.00 148.52 ? 213 ARG L CB  1 
ATOM 4568 C CG  . ARG D 4 212 ? 159.651 163.665 223.879 1.00 148.52 ? 213 ARG L CG  1 
ATOM 4569 C CD  . ARG D 4 212 ? 160.864 162.905 224.370 1.00 148.52 ? 213 ARG L CD  1 
ATOM 4570 N NE  . ARG D 4 212 ? 161.579 163.641 225.404 1.00 148.52 ? 213 ARG L NE  1 
ATOM 4571 C CZ  . ARG D 4 212 ? 161.298 163.568 226.697 1.00 148.52 ? 213 ARG L CZ  1 
ATOM 4572 N NH1 . ARG D 4 212 ? 160.319 162.802 227.148 1.00 148.52 ? 213 ARG L NH1 1 
ATOM 4573 N NH2 . ARG D 4 212 ? 162.017 164.281 227.559 1.00 148.52 ? 213 ARG L NH2 1 
ATOM 4574 N N   . LEU E 5 99  ? 167.656 161.376 90.089  1.00 217.72 ? 35  LEU R N   1 
ATOM 4575 C CA  . LEU E 5 99  ? 168.397 160.367 90.831  1.00 217.95 ? 35  LEU R CA  1 
ATOM 4576 C C   . LEU E 5 99  ? 168.075 160.413 92.324  1.00 217.18 ? 35  LEU R C   1 
ATOM 4577 O O   . LEU E 5 99  ? 167.955 159.372 92.960  1.00 215.90 ? 35  LEU R O   1 
ATOM 4578 C CB  . LEU E 5 99  ? 169.895 160.539 90.599  1.00 216.75 ? 35  LEU R CB  1 
ATOM 4579 C CG  . LEU E 5 99  ? 170.332 160.329 89.149  1.00 216.88 ? 35  LEU R CG  1 
ATOM 4580 C CD1 . LEU E 5 99  ? 171.840 160.444 89.018  1.00 215.92 ? 35  LEU R CD1 1 
ATOM 4581 C CD2 . LEU E 5 99  ? 169.854 158.981 88.640  1.00 216.28 ? 35  LEU R CD2 1 
ATOM 4582 N N   . LEU E 5 100 ? 167.928 161.621 92.879  1.00 215.15 ? 36  LEU R N   1 
ATOM 4583 C CA  . LEU E 5 100 ? 167.554 161.741 94.286  1.00 214.46 ? 36  LEU R CA  1 
ATOM 4584 C C   . LEU E 5 100 ? 166.175 161.149 94.541  1.00 215.50 ? 36  LEU R C   1 
ATOM 4585 O O   . LEU E 5 100 ? 165.926 160.579 95.610  1.00 216.20 ? 36  LEU R O   1 
ATOM 4586 C CB  . LEU E 5 100 ? 167.595 163.208 94.714  1.00 214.31 ? 36  LEU R CB  1 
ATOM 4587 C CG  . LEU E 5 100 ? 168.958 163.893 94.580  1.00 214.31 ? 36  LEU R CG  1 
ATOM 4588 C CD1 . LEU E 5 100 ? 168.843 165.390 94.824  1.00 213.66 ? 36  LEU R CD1 1 
ATOM 4589 C CD2 . LEU E 5 100 ? 169.969 163.272 95.533  1.00 213.78 ? 36  LEU R CD2 1 
ATOM 4590 N N   . ALA E 5 101 ? 165.267 161.279 93.574  1.00 213.08 ? 37  ALA R N   1 
ATOM 4591 C CA  . ALA E 5 101 ? 163.969 160.626 93.687  1.00 211.40 ? 37  ALA R CA  1 
ATOM 4592 C C   . ALA E 5 101 ? 164.120 159.112 93.739  1.00 211.49 ? 37  ALA R C   1 
ATOM 4593 O O   . ALA E 5 101 ? 163.445 158.439 94.525  1.00 211.44 ? 37  ALA R O   1 
ATOM 4594 C CB  . ALA E 5 101 ? 163.071 161.035 92.522  1.00 210.99 ? 37  ALA R CB  1 
ATOM 4595 N N   . ARG E 5 102 ? 165.006 158.557 92.909  1.00 204.55 ? 38  ARG R N   1 
ATOM 4596 C CA  . ARG E 5 102 ? 165.255 157.121 92.964  1.00 204.20 ? 38  ARG R CA  1 
ATOM 4597 C C   . ARG E 5 102 ? 165.900 156.722 94.285  1.00 203.91 ? 38  ARG R C   1 
ATOM 4598 O O   . ARG E 5 102 ? 165.635 155.632 94.800  1.00 203.24 ? 38  ARG R O   1 
ATOM 4599 C CB  . ARG E 5 102 ? 166.130 156.690 91.785  1.00 202.89 ? 38  ARG R CB  1 
ATOM 4600 N N   . ALA E 5 103 ? 166.748 157.584 94.843  1.00 200.96 ? 39  ALA R N   1 
ATOM 4601 C CA  . ALA E 5 103 ? 167.347 157.292 96.141  1.00 200.27 ? 39  ALA R CA  1 
ATOM 4602 C C   . ALA E 5 103 ? 166.292 157.266 97.236  1.00 200.22 ? 39  ALA R C   1 
ATOM 4603 O O   . ALA E 5 103 ? 166.312 156.392 98.113  1.00 199.48 ? 39  ALA R O   1 
ATOM 4604 C CB  . ALA E 5 103 ? 168.429 158.319 96.463  1.00 200.03 ? 39  ALA R CB  1 
ATOM 4605 N N   . GLU E 5 104 ? 165.369 158.224 97.206  1.00 206.30 ? 40  GLU R N   1 
ATOM 4606 C CA  . GLU E 5 104 ? 164.269 158.223 98.162  1.00 206.43 ? 40  GLU R CA  1 
ATOM 4607 C C   . GLU E 5 104 ? 163.397 156.987 97.980  1.00 205.54 ? 40  GLU R C   1 
ATOM 4608 O O   . GLU E 5 104 ? 162.967 156.370 98.962  1.00 205.81 ? 40  GLU R O   1 
ATOM 4609 C CB  . GLU E 5 104 ? 163.450 159.504 98.011  1.00 204.95 ? 40  GLU R CB  1 
ATOM 4610 C CG  . GLU E 5 104 ? 162.330 159.677 99.021  1.00 206.27 ? 40  GLU R CG  1 
ATOM 4611 C CD  . GLU E 5 104 ? 161.768 161.086 99.015  1.00 205.70 ? 40  GLU R CD  1 
ATOM 4612 O OE1 . GLU E 5 104 ? 162.445 161.990 98.481  1.00 204.26 ? 40  GLU R OE1 1 
ATOM 4613 O OE2 . GLU E 5 104 ? 160.654 161.292 99.539  1.00 204.81 ? 40  GLU R OE2 1 
ATOM 4614 N N   . LEU E 5 105 ? 163.144 156.601 96.728  1.00 192.64 ? 41  LEU R N   1 
ATOM 4615 C CA  . LEU E 5 105 ? 162.403 155.375 96.457  1.00 190.71 ? 41  LEU R CA  1 
ATOM 4616 C C   . LEU E 5 105 ? 163.111 154.163 97.043  1.00 190.40 ? 41  LEU R C   1 
ATOM 4617 O O   . LEU E 5 105 ? 162.472 153.283 97.628  1.00 190.84 ? 41  LEU R O   1 
ATOM 4618 C CB  . LEU E 5 105 ? 162.223 155.201 94.952  1.00 190.94 ? 41  LEU R CB  1 
ATOM 4619 C CG  . LEU E 5 105 ? 161.238 156.137 94.256  1.00 190.84 ? 41  LEU R CG  1 
ATOM 4620 C CD1 . LEU E 5 105 ? 161.431 156.094 92.749  1.00 189.67 ? 41  LEU R CD1 1 
ATOM 4621 C CD2 . LEU E 5 105 ? 159.813 155.765 94.618  1.00 190.46 ? 41  LEU R CD2 1 
ATOM 4622 N N   . ALA E 5 106 ? 164.433 154.096 96.882  1.00 183.42 ? 42  ALA R N   1 
ATOM 4623 C CA  . ALA E 5 106 ? 165.196 152.973 97.414  1.00 184.49 ? 42  ALA R CA  1 
ATOM 4624 C C   . ALA E 5 106 ? 165.120 152.925 98.933  1.00 184.74 ? 42  ALA R C   1 
ATOM 4625 O O   . ALA E 5 106 ? 164.915 151.855 99.516  1.00 182.59 ? 42  ALA R O   1 
ATOM 4626 C CB  . ALA E 5 106 ? 166.649 153.063 96.950  1.00 183.61 ? 42  ALA R CB  1 
ATOM 4627 N N   . LEU E 5 107 ? 165.279 154.077 99.592  1.00 172.74 ? 43  LEU R N   1 
ATOM 4628 C CA  . LEU E 5 107 ? 165.200 154.106 101.051 1.00 169.86 ? 43  LEU R CA  1 
ATOM 4629 C C   . LEU E 5 107 ? 163.819 153.681 101.537 1.00 169.24 ? 43  LEU R C   1 
ATOM 4630 O O   . LEU E 5 107 ? 163.700 152.906 102.494 1.00 169.59 ? 43  LEU R O   1 
ATOM 4631 C CB  . LEU E 5 107 ? 165.540 155.498 101.575 1.00 168.49 ? 43  LEU R CB  1 
ATOM 4632 C CG  . LEU E 5 107 ? 167.004 155.912 101.472 1.00 170.83 ? 43  LEU R CG  1 
ATOM 4633 C CD1 . LEU E 5 107 ? 167.217 157.290 102.086 1.00 170.50 ? 43  LEU R CD1 1 
ATOM 4634 C CD2 . LEU E 5 107 ? 167.876 154.875 102.148 1.00 169.91 ? 43  LEU R CD2 1 
ATOM 4635 N N   . LEU E 5 108 ? 162.763 154.173 100.882 1.00 169.95 ? 44  LEU R N   1 
ATOM 4636 C CA  . LEU E 5 108 ? 161.408 153.803 101.277 1.00 170.49 ? 44  LEU R CA  1 
ATOM 4637 C C   . LEU E 5 108 ? 161.148 152.320 101.052 1.00 174.90 ? 44  LEU R C   1 
ATOM 4638 O O   . LEU E 5 108 ? 160.537 151.657 101.897 1.00 177.65 ? 44  LEU R O   1 
ATOM 4639 C CB  . LEU E 5 108 ? 160.392 154.642 100.508 1.00 167.46 ? 44  LEU R CB  1 
ATOM 4640 C CG  . LEU E 5 108 ? 160.485 156.153 100.710 1.00 169.29 ? 44  LEU R CG  1 
ATOM 4641 C CD1 . LEU E 5 108 ? 159.765 156.870 99.580  1.00 174.38 ? 44  LEU R CD1 1 
ATOM 4642 C CD2 . LEU E 5 108 ? 159.948 156.570 102.072 1.00 168.75 ? 44  LEU R CD2 1 
ATOM 4643 N N   . SER E 5 109 ? 161.596 151.783 99.916  1.00 173.63 ? 45  SER R N   1 
ATOM 4644 C CA  . SER E 5 109 ? 161.391 150.367 99.638  1.00 171.18 ? 45  SER R CA  1 
ATOM 4645 C C   . SER E 5 109 ? 162.149 149.501 100.632 1.00 168.61 ? 45  SER R C   1 
ATOM 4646 O O   . SER E 5 109 ? 161.646 148.461 101.070 1.00 169.44 ? 45  SER R O   1 
ATOM 4647 C CB  . SER E 5 109 ? 161.815 150.046 98.206  1.00 172.33 ? 45  SER R CB  1 
ATOM 4648 O OG  . SER E 5 109 ? 161.011 150.739 97.265  1.00 174.77 ? 45  SER R OG  1 
ATOM 4649 N N   . ILE E 5 110 ? 163.363 149.914 101.002 1.00 148.20 ? 46  ILE R N   1 
ATOM 4650 C CA  . ILE E 5 110 ? 164.126 149.171 101.996 1.00 150.13 ? 46  ILE R CA  1 
ATOM 4651 C C   . ILE E 5 110 ? 163.424 149.214 103.344 1.00 149.12 ? 46  ILE R C   1 
ATOM 4652 O O   . ILE E 5 110 ? 163.366 148.207 104.059 1.00 150.72 ? 46  ILE R O   1 
ATOM 4653 C CB  . ILE E 5 110 ? 165.563 149.714 102.080 1.00 149.20 ? 46  ILE R CB  1 
ATOM 4654 C CG1 . ILE E 5 110 ? 166.318 149.372 100.799 1.00 149.44 ? 46  ILE R CG1 1 
ATOM 4655 C CG2 . ILE E 5 110 ? 166.282 149.133 103.280 1.00 150.32 ? 46  ILE R CG2 1 
ATOM 4656 C CD1 . ILE E 5 110 ? 167.707 149.938 100.747 1.00 149.49 ? 46  ILE R CD1 1 
ATOM 4657 N N   . VAL E 5 111 ? 162.888 150.375 103.720 1.00 131.62 ? 47  VAL R N   1 
ATOM 4658 C CA  . VAL E 5 111 ? 162.166 150.466 104.986 1.00 131.22 ? 47  VAL R CA  1 
ATOM 4659 C C   . VAL E 5 111 ? 160.954 149.547 104.969 1.00 133.28 ? 47  VAL R C   1 
ATOM 4660 O O   . VAL E 5 111 ? 160.687 148.823 105.940 1.00 144.44 ? 47  VAL R O   1 
ATOM 4661 C CB  . VAL E 5 111 ? 161.766 151.925 105.276 1.00 130.72 ? 47  VAL R CB  1 
ATOM 4662 C CG1 . VAL E 5 111 ? 160.697 151.979 106.360 1.00 129.84 ? 47  VAL R CG1 1 
ATOM 4663 C CG2 . VAL E 5 111 ? 162.981 152.736 105.692 1.00 135.99 ? 47  VAL R CG2 1 
ATOM 4664 N N   . PHE E 5 112 ? 160.204 149.562 103.865 1.00 134.16 ? 48  PHE R N   1 
ATOM 4665 C CA  . PHE E 5 112 ? 159.046 148.685 103.734 1.00 137.53 ? 48  PHE R CA  1 
ATOM 4666 C C   . PHE E 5 112 ? 159.457 147.227 103.860 1.00 143.23 ? 48  PHE R C   1 
ATOM 4667 O O   . PHE E 5 112 ? 158.808 146.444 104.565 1.00 146.66 ? 48  PHE R O   1 
ATOM 4668 C CB  . PHE E 5 112 ? 158.354 148.934 102.394 1.00 139.78 ? 48  PHE R CB  1 
ATOM 4669 C CG  . PHE E 5 112 ? 157.200 148.014 102.127 1.00 142.47 ? 48  PHE R CG  1 
ATOM 4670 C CD1 . PHE E 5 112 ? 155.990 148.195 102.774 1.00 143.80 ? 48  PHE R CD1 1 
ATOM 4671 C CD2 . PHE E 5 112 ? 157.322 146.977 101.221 1.00 143.51 ? 48  PHE R CD2 1 
ATOM 4672 C CE1 . PHE E 5 112 ? 154.924 147.352 102.528 1.00 142.06 ? 48  PHE R CE1 1 
ATOM 4673 C CE2 . PHE E 5 112 ? 156.261 146.131 100.967 1.00 143.31 ? 48  PHE R CE2 1 
ATOM 4674 C CZ  . PHE E 5 112 ? 155.060 146.319 101.622 1.00 142.97 ? 48  PHE R CZ  1 
ATOM 4675 N N   . VAL E 5 113 ? 160.545 146.849 103.188 1.00 139.21 ? 49  VAL R N   1 
ATOM 4676 C CA  . VAL E 5 113 ? 161.029 145.475 103.257 1.00 136.40 ? 49  VAL R CA  1 
ATOM 4677 C C   . VAL E 5 113 ? 161.368 145.105 104.693 1.00 136.11 ? 49  VAL R C   1 
ATOM 4678 O O   . VAL E 5 113 ? 160.924 144.072 105.203 1.00 135.22 ? 49  VAL R O   1 
ATOM 4679 C CB  . VAL E 5 113 ? 162.238 145.285 102.326 1.00 137.00 ? 49  VAL R CB  1 
ATOM 4680 C CG1 . VAL E 5 113 ? 162.982 144.007 102.671 1.00 137.94 ? 49  VAL R CG1 1 
ATOM 4681 C CG2 . VAL E 5 113 ? 161.786 145.264 100.878 1.00 137.51 ? 49  VAL R CG2 1 
ATOM 4682 N N   . ALA E 5 114 ? 162.136 145.954 105.376 1.00 130.64 ? 50  ALA R N   1 
ATOM 4683 C CA  . ALA E 5 114 ? 162.565 145.627 106.731 1.00 130.17 ? 50  ALA R CA  1 
ATOM 4684 C C   . ALA E 5 114 ? 161.368 145.445 107.651 1.00 126.53 ? 50  ALA R C   1 
ATOM 4685 O O   . ALA E 5 114 ? 161.277 144.450 108.380 1.00 130.56 ? 50  ALA R O   1 
ATOM 4686 C CB  . ALA E 5 114 ? 163.499 146.707 107.270 1.00 129.81 ? 50  ALA R CB  1 
ATOM 4687 N N   . VAL E 5 115 ? 160.412 146.374 107.598 1.00 116.34 ? 51  VAL R N   1 
ATOM 4688 C CA  . VAL E 5 115 ? 159.286 146.307 108.525 1.00 117.02 ? 51  VAL R CA  1 
ATOM 4689 C C   . VAL E 5 115 ? 158.408 145.101 108.215 1.00 117.87 ? 51  VAL R C   1 
ATOM 4690 O O   . VAL E 5 115 ? 158.110 144.284 109.100 1.00 128.27 ? 51  VAL R O   1 
ATOM 4691 C CB  . VAL E 5 115 ? 158.482 147.617 108.489 1.00 115.90 ? 51  VAL R CB  1 
ATOM 4692 C CG1 . VAL E 5 115 ? 157.360 147.582 109.513 1.00 112.81 ? 51  VAL R CG1 1 
ATOM 4693 C CG2 . VAL E 5 115 ? 159.390 148.798 108.749 1.00 117.91 ? 51  VAL R CG2 1 
ATOM 4694 N N   . ALA E 5 116 ? 158.000 144.956 106.949 1.00 116.52 ? 52  ALA R N   1 
ATOM 4695 C CA  . ALA E 5 116 ? 157.108 143.864 106.587 1.00 123.84 ? 52  ALA R CA  1 
ATOM 4696 C C   . ALA E 5 116 ? 157.753 142.518 106.868 1.00 128.02 ? 52  ALA R C   1 
ATOM 4697 O O   . ALA E 5 116 ? 157.105 141.617 107.408 1.00 124.09 ? 52  ALA R O   1 
ATOM 4698 C CB  . ALA E 5 116 ? 156.712 143.972 105.116 1.00 127.69 ? 52  ALA R CB  1 
ATOM 4699 N N   . LEU E 5 117 ? 159.038 142.370 106.541 1.00 129.72 ? 53  LEU R N   1 
ATOM 4700 C CA  . LEU E 5 117 ? 159.707 141.091 106.722 1.00 126.28 ? 53  LEU R CA  1 
ATOM 4701 C C   . LEU E 5 117 ? 159.881 140.761 108.195 1.00 128.32 ? 53  LEU R C   1 
ATOM 4702 O O   . LEU E 5 117 ? 159.580 139.643 108.624 1.00 130.08 ? 53  LEU R O   1 
ATOM 4703 C CB  . LEU E 5 117 ? 161.058 141.108 106.014 1.00 125.44 ? 53  LEU R CB  1 
ATOM 4704 C CG  . LEU E 5 117 ? 161.821 139.789 106.014 1.00 129.87 ? 53  LEU R CG  1 
ATOM 4705 C CD1 . LEU E 5 117 ? 161.022 138.718 105.297 1.00 129.20 ? 53  LEU R CD1 1 
ATOM 4706 C CD2 . LEU E 5 117 ? 163.180 139.974 105.366 1.00 128.84 ? 53  LEU R CD2 1 
ATOM 4707 N N   . SER E 5 118 ? 160.371 141.717 108.992 1.00 120.16 ? 54  SER R N   1 
ATOM 4708 C CA  . SER E 5 118 ? 160.568 141.441 110.409 1.00 115.68 ? 54  SER R CA  1 
ATOM 4709 C C   . SER E 5 118 ? 159.252 141.081 111.083 1.00 112.17 ? 54  SER R C   1 
ATOM 4710 O O   . SER E 5 118 ? 159.177 140.098 111.834 1.00 118.08 ? 54  SER R O   1 
ATOM 4711 C CB  . SER E 5 118 ? 161.216 142.644 111.091 1.00 117.22 ? 54  SER R CB  1 
ATOM 4712 O OG  . SER E 5 118 ? 162.470 142.940 110.502 1.00 122.05 ? 54  SER R OG  1 
ATOM 4713 N N   . ASN E 5 119 ? 158.186 141.829 110.794 1.00 118.57 ? 55  ASN R N   1 
ATOM 4714 C CA  . ASN E 5 119 ? 156.935 141.551 111.488 1.00 124.27 ? 55  ASN R CA  1 
ATOM 4715 C C   . ASN E 5 119 ? 156.270 140.277 110.969 1.00 131.53 ? 55  ASN R C   1 
ATOM 4716 O O   . ASN E 5 119 ? 155.684 139.521 111.754 1.00 138.14 ? 55  ASN R O   1 
ATOM 4717 C CB  . ASN E 5 119 ? 156.001 142.754 111.395 1.00 129.56 ? 55  ASN R CB  1 
ATOM 4718 C CG  . ASN E 5 119 ? 156.492 143.930 112.226 1.00 133.55 ? 55  ASN R CG  1 
ATOM 4719 O OD1 . ASN E 5 119 ? 156.490 143.881 113.457 1.00 127.78 ? 55  ASN R OD1 1 
ATOM 4720 N ND2 . ASN E 5 119 ? 156.916 144.991 111.555 1.00 139.48 ? 55  ASN R ND2 1 
ATOM 4721 N N   . GLY E 5 120 ? 156.367 140.000 109.664 1.00 134.01 ? 56  GLY R N   1 
ATOM 4722 C CA  . GLY E 5 120 ? 155.864 138.736 109.155 1.00 136.57 ? 56  GLY R CA  1 
ATOM 4723 C C   . GLY E 5 120 ? 156.595 137.545 109.741 1.00 136.26 ? 56  GLY R C   1 
ATOM 4724 O O   . GLY E 5 120 ? 155.981 136.525 110.057 1.00 133.30 ? 56  GLY R O   1 
ATOM 4725 N N   . LEU E 5 121 ? 157.916 137.658 109.900 1.00 124.71 ? 57  LEU R N   1 
ATOM 4726 C CA  . LEU E 5 121 ? 158.684 136.574 110.498 1.00 122.03 ? 57  LEU R CA  1 
ATOM 4727 C C   . LEU E 5 121 ? 158.323 136.377 111.965 1.00 123.45 ? 57  LEU R C   1 
ATOM 4728 O O   . LEU E 5 121 ? 158.229 135.239 112.437 1.00 126.06 ? 57  LEU R O   1 
ATOM 4729 C CB  . LEU E 5 121 ? 160.176 136.844 110.338 1.00 120.16 ? 57  LEU R CB  1 
ATOM 4730 C CG  . LEU E 5 121 ? 160.686 136.724 108.903 1.00 119.71 ? 57  LEU R CG  1 
ATOM 4731 C CD1 . LEU E 5 121 ? 162.162 137.054 108.842 1.00 121.50 ? 57  LEU R CD1 1 
ATOM 4732 C CD2 . LEU E 5 121 ? 160.425 135.337 108.350 1.00 121.48 ? 57  LEU R CD2 1 
ATOM 4733 N N   . VAL E 5 122 ? 158.115 137.468 112.705 1.00 109.55 ? 58  VAL R N   1 
ATOM 4734 C CA  . VAL E 5 122 ? 157.702 137.322 114.099 1.00 104.31 ? 58  VAL R CA  1 
ATOM 4735 C C   . VAL E 5 122 ? 156.327 136.666 114.185 1.00 104.15 ? 58  VAL R C   1 
ATOM 4736 O O   . VAL E 5 122 ? 156.090 135.792 115.032 1.00 111.56 ? 58  VAL R O   1 
ATOM 4737 C CB  . VAL E 5 122 ? 157.730 138.682 114.818 1.00 105.09 ? 58  VAL R CB  1 
ATOM 4738 C CG1 . VAL E 5 122 ? 157.185 138.540 116.229 1.00 106.42 ? 58  VAL R CG1 1 
ATOM 4739 C CG2 . VAL E 5 122 ? 159.146 139.222 114.862 1.00 107.89 ? 58  VAL R CG2 1 
ATOM 4740 N N   . LEU E 5 123 ? 155.399 137.076 113.314 1.00 111.99 ? 59  LEU R N   1 
ATOM 4741 C CA  . LEU E 5 123 ? 154.072 136.465 113.301 1.00 115.92 ? 59  LEU R CA  1 
ATOM 4742 C C   . LEU E 5 123 ? 154.137 134.993 112.914 1.00 124.64 ? 59  LEU R C   1 
ATOM 4743 O O   . LEU E 5 123 ? 153.382 134.172 113.444 1.00 125.20 ? 59  LEU R O   1 
ATOM 4744 C CB  . LEU E 5 123 ? 153.150 137.225 112.349 1.00 118.30 ? 59  LEU R CB  1 
ATOM 4745 C CG  . LEU E 5 123 ? 152.637 138.561 112.882 1.00 121.72 ? 59  LEU R CG  1 
ATOM 4746 C CD1 . LEU E 5 123 ? 151.870 139.296 111.805 1.00 121.89 ? 59  LEU R CD1 1 
ATOM 4747 C CD2 . LEU E 5 123 ? 151.764 138.338 114.103 1.00 117.48 ? 59  LEU R CD2 1 
ATOM 4748 N N   . ALA E 5 124 ? 155.022 134.642 111.978 1.00 136.36 ? 60  ALA R N   1 
ATOM 4749 C CA  . ALA E 5 124 ? 155.205 133.242 111.610 1.00 136.02 ? 60  ALA R CA  1 
ATOM 4750 C C   . ALA E 5 124 ? 155.772 132.434 112.772 1.00 132.79 ? 60  ALA R C   1 
ATOM 4751 O O   . ALA E 5 124 ? 155.370 131.286 112.991 1.00 130.91 ? 60  ALA R O   1 
ATOM 4752 C CB  . ALA E 5 124 ? 156.118 133.135 110.389 1.00 135.00 ? 60  ALA R CB  1 
ATOM 4753 N N   . ALA E 5 125 ? 156.721 133.008 113.513 1.00 120.29 ? 61  ALA R N   1 
ATOM 4754 C CA  . ALA E 5 125 ? 157.258 132.316 114.679 1.00 117.35 ? 61  ALA R CA  1 
ATOM 4755 C C   . ALA E 5 125 ? 156.175 132.094 115.726 1.00 119.66 ? 61  ALA R C   1 
ATOM 4756 O O   . ALA E 5 125 ? 156.099 131.021 116.336 1.00 123.21 ? 61  ALA R O   1 
ATOM 4757 C CB  . ALA E 5 125 ? 158.426 133.105 115.268 1.00 117.24 ? 61  ALA R CB  1 
ATOM 4758 N N   . LEU E 5 126 ? 155.325 133.100 115.944 1.00 121.45 ? 62  LEU R N   1 
ATOM 4759 C CA  . LEU E 5 126 ? 154.209 132.935 116.871 1.00 124.63 ? 62  LEU R CA  1 
ATOM 4760 C C   . LEU E 5 126 ? 153.233 131.867 116.382 1.00 128.08 ? 62  LEU R C   1 
ATOM 4761 O O   . LEU E 5 126 ? 152.748 131.050 117.174 1.00 129.04 ? 62  LEU R O   1 
ATOM 4762 C CB  . LEU E 5 126 ? 153.496 134.271 117.074 1.00 122.96 ? 62  LEU R CB  1 
ATOM 4763 C CG  . LEU E 5 126 ? 154.306 135.350 117.796 1.00 118.04 ? 62  LEU R CG  1 
ATOM 4764 C CD1 . LEU E 5 126 ? 153.622 136.700 117.697 1.00 118.26 ? 62  LEU R CD1 1 
ATOM 4765 C CD2 . LEU E 5 126 ? 154.517 134.973 119.250 1.00 120.42 ? 62  LEU R CD2 1 
ATOM 4766 N N   . ALA E 5 127 ? 152.944 131.851 115.079 1.00 133.27 ? 63  ALA R N   1 
ATOM 4767 C CA  . ALA E 5 127 ? 152.057 130.830 114.529 1.00 134.63 ? 63  ALA R CA  1 
ATOM 4768 C C   . ALA E 5 127 ? 152.641 129.434 114.708 1.00 137.90 ? 63  ALA R C   1 
ATOM 4769 O O   . ALA E 5 127 ? 151.916 128.487 115.034 1.00 137.75 ? 63  ALA R O   1 
ATOM 4770 C CB  . ALA E 5 127 ? 151.785 131.112 113.051 1.00 132.82 ? 63  ALA R CB  1 
ATOM 4771 N N   . ARG E 5 128 ? 153.949 129.285 114.488 1.00 149.76 ? 64  ARG R N   1 
ATOM 4772 C CA  . ARG E 5 128 ? 154.587 127.986 114.677 1.00 150.64 ? 64  ARG R CA  1 
ATOM 4773 C C   . ARG E 5 128 ? 154.567 127.569 116.142 1.00 151.61 ? 64  ARG R C   1 
ATOM 4774 O O   . ARG E 5 128 ? 154.322 126.399 116.455 1.00 153.45 ? 64  ARG R O   1 
ATOM 4775 C CB  . ARG E 5 128 ? 156.017 128.018 114.146 1.00 152.01 ? 64  ARG R CB  1 
ATOM 4776 N N   . ARG E 5 129 ? 154.818 128.508 117.055 1.00 154.37 ? 65  ARG R N   1 
ATOM 4777 C CA  . ARG E 5 129 ? 154.628 128.200 118.466 1.00 156.06 ? 65  ARG R CA  1 
ATOM 4778 C C   . ARG E 5 129 ? 153.197 127.777 118.736 1.00 156.58 ? 65  ARG R C   1 
ATOM 4779 O O   . ARG E 5 129 ? 152.945 126.970 119.635 1.00 156.60 ? 65  ARG R O   1 
ATOM 4780 C CB  . ARG E 5 129 ? 154.996 129.405 119.330 1.00 154.41 ? 65  ARG R CB  1 
ATOM 4781 N N   . GLY E 5 130 ? 152.250 128.292 117.953 1.00 160.81 ? 66  GLY R N   1 
ATOM 4782 C CA  . GLY E 5 130 ? 150.863 127.902 118.110 1.00 162.18 ? 66  GLY R CA  1 
ATOM 4783 C C   . GLY E 5 130 ? 150.630 126.411 117.988 1.00 164.15 ? 66  GLY R C   1 
ATOM 4784 O O   . GLY E 5 130 ? 149.581 125.919 118.421 1.00 166.38 ? 66  GLY R O   1 
ATOM 4785 N N   . ARG E 5 131 ? 151.582 125.677 117.404 1.00 160.37 ? 67  ARG R N   1 
ATOM 4786 C CA  . ARG E 5 131 ? 151.457 124.226 117.328 1.00 159.43 ? 67  ARG R CA  1 
ATOM 4787 C C   . ARG E 5 131 ? 151.435 123.582 118.704 1.00 160.23 ? 67  ARG R C   1 
ATOM 4788 O O   . ARG E 5 131 ? 150.914 122.472 118.851 1.00 158.75 ? 67  ARG R O   1 
ATOM 4789 C CB  . ARG E 5 131 ? 152.603 123.630 116.510 1.00 158.56 ? 67  ARG R CB  1 
ATOM 4790 N N   . ARG E 5 132 ? 151.987 124.250 119.711 1.00 161.46 ? 68  ARG R N   1 
ATOM 4791 C CA  . ARG E 5 132 ? 152.085 123.706 121.056 1.00 162.09 ? 68  ARG R CA  1 
ATOM 4792 C C   . ARG E 5 132 ? 150.964 124.188 121.966 1.00 161.96 ? 68  ARG R C   1 
ATOM 4793 O O   . ARG E 5 132 ? 151.012 123.938 123.174 1.00 161.81 ? 68  ARG R O   1 
ATOM 4794 C CB  . ARG E 5 132 ? 153.443 124.063 121.665 1.00 160.13 ? 68  ARG R CB  1 
ATOM 4795 N N   . GLY E 5 133 ? 149.966 124.877 121.417 1.00 154.93 ? 69  GLY R N   1 
ATOM 4796 C CA  . GLY E 5 133 ? 148.906 125.435 122.229 1.00 152.70 ? 69  GLY R CA  1 
ATOM 4797 C C   . GLY E 5 133 ? 149.297 126.667 123.002 1.00 151.98 ? 69  GLY R C   1 
ATOM 4798 O O   . GLY E 5 133 ? 148.612 127.024 123.965 1.00 148.41 ? 69  GLY R O   1 
ATOM 4799 N N   . HIS E 5 134 ? 150.387 127.330 122.611 1.00 167.56 ? 70  HIS R N   1 
ATOM 4800 C CA  . HIS E 5 134 ? 150.964 128.429 123.383 1.00 166.20 ? 70  HIS R CA  1 
ATOM 4801 C C   . HIS E 5 134 ? 150.215 129.732 123.101 1.00 164.63 ? 70  HIS R C   1 
ATOM 4802 O O   . HIS E 5 134 ? 150.736 130.679 122.511 1.00 162.44 ? 70  HIS R O   1 
ATOM 4803 C CB  . HIS E 5 134 ? 152.447 128.574 123.065 1.00 167.80 ? 70  HIS R CB  1 
ATOM 4804 N N   . TRP E 5 135 ? 148.963 129.781 123.554 1.00 151.85 ? 71  TRP R N   1 
ATOM 4805 C CA  . TRP E 5 135 ? 148.231 131.045 123.586 1.00 152.46 ? 71  TRP R CA  1 
ATOM 4806 C C   . TRP E 5 135 ? 148.604 131.803 124.862 1.00 153.10 ? 71  TRP R C   1 
ATOM 4807 O O   . TRP E 5 135 ? 147.772 132.150 125.699 1.00 153.80 ? 71  TRP R O   1 
ATOM 4808 C CB  . TRP E 5 135 ? 146.729 130.815 123.476 1.00 152.20 ? 71  TRP R CB  1 
ATOM 4809 C CG  . TRP E 5 135 ? 145.940 132.079 123.187 1.00 152.42 ? 71  TRP R CG  1 
ATOM 4810 C CD1 . TRP E 5 135 ? 145.311 132.879 124.097 1.00 152.71 ? 71  TRP R CD1 1 
ATOM 4811 C CD2 . TRP E 5 135 ? 145.704 132.678 121.901 1.00 152.64 ? 71  TRP R CD2 1 
ATOM 4812 N NE1 . TRP E 5 135 ? 144.701 133.933 123.461 1.00 152.18 ? 71  TRP R NE1 1 
ATOM 4813 C CE2 . TRP E 5 135 ? 144.928 133.833 122.113 1.00 152.68 ? 71  TRP R CE2 1 
ATOM 4814 C CE3 . TRP E 5 135 ? 146.075 132.349 120.595 1.00 152.52 ? 71  TRP R CE3 1 
ATOM 4815 C CZ2 . TRP E 5 135 ? 144.516 134.661 121.067 1.00 150.40 ? 71  TRP R CZ2 1 
ATOM 4816 C CZ3 . TRP E 5 135 ? 145.662 133.172 119.558 1.00 151.66 ? 71  TRP R CZ3 1 
ATOM 4817 C CH2 . TRP E 5 135 ? 144.893 134.313 119.801 1.00 149.82 ? 71  TRP R CH2 1 
ATOM 4818 N N   . ALA E 5 136 ? 149.904 132.037 125.002 1.00 136.27 ? 72  ALA R N   1 
ATOM 4819 C CA  . ALA E 5 136 ? 150.412 132.783 126.135 1.00 134.34 ? 72  ALA R CA  1 
ATOM 4820 C C   . ALA E 5 136 ? 150.012 134.248 125.998 1.00 135.25 ? 72  ALA R C   1 
ATOM 4821 O O   . ALA E 5 136 ? 149.892 134.760 124.885 1.00 140.54 ? 72  ALA R O   1 
ATOM 4822 C CB  . ALA E 5 136 ? 151.931 132.657 126.222 1.00 131.33 ? 72  ALA R CB  1 
ATOM 4823 N N   . PRO E 5 137 ? 149.778 134.939 127.116 1.00 125.11 ? 73  PRO R N   1 
ATOM 4824 C CA  . PRO E 5 137 ? 149.324 136.336 127.020 1.00 126.60 ? 73  PRO R CA  1 
ATOM 4825 C C   . PRO E 5 137 ? 150.254 137.224 126.218 1.00 128.70 ? 73  PRO R C   1 
ATOM 4826 O O   . PRO E 5 137 ? 149.781 138.047 125.424 1.00 133.13 ? 73  PRO R O   1 
ATOM 4827 C CB  . PRO E 5 137 ? 149.254 136.779 128.487 1.00 127.23 ? 73  PRO R CB  1 
ATOM 4828 C CG  . PRO E 5 137 ? 149.087 135.518 129.253 1.00 129.78 ? 73  PRO R CG  1 
ATOM 4829 C CD  . PRO E 5 137 ? 149.868 134.482 128.510 1.00 126.11 ? 73  PRO R CD  1 
ATOM 4830 N N   . ILE E 5 138 ? 151.567 137.063 126.381 1.00 119.67 ? 74  ILE R N   1 
ATOM 4831 C CA  . ILE E 5 138 ? 152.507 137.954 125.712 1.00 119.40 ? 74  ILE R CA  1 
ATOM 4832 C C   . ILE E 5 138 ? 152.454 137.761 124.204 1.00 120.93 ? 74  ILE R C   1 
ATOM 4833 O O   . ILE E 5 138 ? 152.736 138.697 123.437 1.00 125.06 ? 74  ILE R O   1 
ATOM 4834 C CB  . ILE E 5 138 ? 153.924 137.730 126.274 1.00 122.88 ? 74  ILE R CB  1 
ATOM 4835 C CG1 . ILE E 5 138 ? 154.924 138.720 125.670 1.00 125.66 ? 74  ILE R CG1 1 
ATOM 4836 C CG2 . ILE E 5 138 ? 154.369 136.296 126.045 1.00 124.86 ? 74  ILE R CG2 1 
ATOM 4837 C CD1 . ILE E 5 138 ? 156.360 138.477 126.104 1.00 123.05 ? 74  ILE R CD1 1 
ATOM 4838 N N   . HIS E 5 139 ? 152.085 136.563 123.749 1.00 128.23 ? 75  HIS R N   1 
ATOM 4839 C CA  . HIS E 5 139 ? 152.117 136.275 122.320 1.00 131.17 ? 75  HIS R CA  1 
ATOM 4840 C C   . HIS E 5 139 ? 151.087 137.091 121.557 1.00 129.89 ? 75  HIS R C   1 
ATOM 4841 O O   . HIS E 5 139 ? 151.381 137.602 120.474 1.00 130.78 ? 75  HIS R O   1 
ATOM 4842 C CB  . HIS E 5 139 ? 151.891 134.787 122.074 1.00 132.20 ? 75  HIS R CB  1 
ATOM 4843 C CG  . HIS E 5 139 ? 153.065 133.933 122.426 1.00 134.23 ? 75  HIS R CG  1 
ATOM 4844 N ND1 . HIS E 5 139 ? 153.039 132.559 122.326 1.00 137.32 ? 75  HIS R ND1 1 
ATOM 4845 C CD2 . HIS E 5 139 ? 154.301 134.256 122.872 1.00 132.61 ? 75  HIS R CD2 1 
ATOM 4846 C CE1 . HIS E 5 139 ? 154.209 132.072 122.699 1.00 136.45 ? 75  HIS R CE1 1 
ATOM 4847 N NE2 . HIS E 5 139 ? 154.992 133.080 123.035 1.00 137.46 ? 75  HIS R NE2 1 
ATOM 4848 N N   . VAL E 5 140 ? 149.871 137.215 122.092 1.00 116.58 ? 76  VAL R N   1 
ATOM 4849 C CA  . VAL E 5 140 ? 148.833 137.935 121.364 1.00 120.42 ? 76  VAL R CA  1 
ATOM 4850 C C   . VAL E 5 140 ? 149.160 139.419 121.310 1.00 126.79 ? 76  VAL R C   1 
ATOM 4851 O O   . VAL E 5 140 ? 148.960 140.077 120.280 1.00 132.02 ? 76  VAL R O   1 
ATOM 4852 C CB  . VAL E 5 140 ? 147.452 137.677 121.990 1.00 120.44 ? 76  VAL R CB  1 
ATOM 4853 C CG1 . VAL E 5 140 ? 146.371 137.797 120.933 1.00 121.91 ? 76  VAL R CG1 1 
ATOM 4854 C CG2 . VAL E 5 140 ? 147.419 136.309 122.627 1.00 128.32 ? 76  VAL R CG2 1 
ATOM 4855 N N   . PHE E 5 141 ? 149.692 139.964 122.406 1.00 118.22 ? 77  PHE R N   1 
ATOM 4856 C CA  . PHE E 5 141 ? 150.054 141.377 122.432 1.00 114.98 ? 77  PHE R CA  1 
ATOM 4857 C C   . PHE E 5 141 ? 151.121 141.689 121.396 1.00 114.62 ? 77  PHE R C   1 
ATOM 4858 O O   . PHE E 5 141 ? 150.972 142.623 120.602 1.00 116.02 ? 77  PHE R O   1 
ATOM 4859 C CB  . PHE E 5 141 ? 150.540 141.778 123.824 1.00 116.06 ? 77  PHE R CB  1 
ATOM 4860 N N   . ILE E 5 142 ? 152.215 140.918 121.391 1.00 105.88 ? 78  ILE R N   1 
ATOM 4861 C CA  . ILE E 5 142 ? 153.283 141.215 120.441 1.00 106.04 ? 78  ILE R CA  1 
ATOM 4862 C C   . ILE E 5 142 ? 152.854 140.871 119.025 1.00 106.35 ? 78  ILE R C   1 
ATOM 4863 O O   . ILE E 5 142 ? 153.297 141.508 118.065 1.00 105.07 ? 78  ILE R O   1 
ATOM 4864 C CB  . ILE E 5 142 ? 154.579 140.487 120.835 1.00 105.39 ? 78  ILE R CB  1 
ATOM 4865 C CG1 . ILE E 5 142 ? 155.736 141.000 119.984 1.00 108.43 ? 78  ILE R CG1 1 
ATOM 4866 C CG2 . ILE E 5 142 ? 154.425 138.986 120.686 1.00 106.68 ? 78  ILE R CG2 1 
ATOM 4867 C CD1 . ILE E 5 142 ? 156.067 142.451 120.222 1.00 107.83 ? 78  ILE R CD1 1 
ATOM 4868 N N   . GLY E 5 143 ? 151.986 139.873 118.863 1.00 117.35 ? 79  GLY R N   1 
ATOM 4869 C CA  . GLY E 5 143 ? 151.470 139.575 117.543 1.00 120.48 ? 79  GLY R CA  1 
ATOM 4870 C C   . GLY E 5 143 ? 150.678 140.729 116.968 1.00 125.86 ? 79  GLY R C   1 
ATOM 4871 O O   . GLY E 5 143 ? 150.855 141.104 115.808 1.00 133.08 ? 79  GLY R O   1 
ATOM 4872 N N   . HIS E 5 144 ? 149.800 141.320 117.774 1.00 106.73 ? 80  HIS R N   1 
ATOM 4873 C CA  . HIS E 5 144 ? 149.039 142.456 117.280 1.00 104.09 ? 80  HIS R CA  1 
ATOM 4874 C C   . HIS E 5 144 ? 149.880 143.723 117.214 1.00 106.17 ? 80  HIS R C   1 
ATOM 4875 O O   . HIS E 5 144 ? 149.575 144.613 116.417 1.00 107.19 ? 80  HIS R O   1 
ATOM 4876 C CB  . HIS E 5 144 ? 147.786 142.657 118.131 1.00 103.24 ? 80  HIS R CB  1 
ATOM 4877 C CG  . HIS E 5 144 ? 146.692 141.689 117.807 1.00 104.79 ? 80  HIS R CG  1 
ATOM 4878 N ND1 . HIS E 5 144 ? 145.835 141.867 116.743 1.00 109.36 ? 80  HIS R ND1 1 
ATOM 4879 C CD2 . HIS E 5 144 ? 146.327 140.525 118.393 1.00 107.39 ? 80  HIS R CD2 1 
ATOM 4880 C CE1 . HIS E 5 144 ? 144.982 140.860 116.694 1.00 111.19 ? 80  HIS R CE1 1 
ATOM 4881 N NE2 . HIS E 5 144 ? 145.258 140.032 117.685 1.00 113.28 ? 80  HIS R NE2 1 
ATOM 4882 N N   . LEU E 5 145 ? 150.951 143.816 118.002 1.00 101.32 ? 81  LEU R N   1 
ATOM 4883 C CA  . LEU E 5 145 ? 151.901 144.906 117.806 1.00 101.97 ? 81  LEU R CA  1 
ATOM 4884 C C   . LEU E 5 145 ? 152.587 144.786 116.452 1.00 103.07 ? 81  LEU R C   1 
ATOM 4885 O O   . LEU E 5 145 ? 152.747 145.780 115.733 1.00 107.15 ? 81  LEU R O   1 
ATOM 4886 C CB  . LEU E 5 145 ? 152.935 144.916 118.931 1.00 105.81 ? 81  LEU R CB  1 
ATOM 4887 C CG  . LEU E 5 145 ? 154.059 145.942 118.774 1.00 106.73 ? 81  LEU R CG  1 
ATOM 4888 C CD1 . LEU E 5 145 ? 153.497 147.344 118.589 1.00 104.43 ? 81  LEU R CD1 1 
ATOM 4889 C CD2 . LEU E 5 145 ? 154.995 145.902 119.966 1.00 100.55 ? 81  LEU R CD2 1 
ATOM 4890 N N   . CYS E 5 146 ? 152.996 143.573 116.087 1.00 102.41 ? 82  CYS R N   1 
ATOM 4891 C CA  . CYS E 5 146 ? 153.571 143.351 114.768 1.00 102.33 ? 82  CYS R CA  1 
ATOM 4892 C C   . CYS E 5 146 ? 152.537 143.571 113.674 1.00 111.27 ? 82  CYS R C   1 
ATOM 4893 O O   . CYS E 5 146 ? 152.876 144.046 112.588 1.00 118.61 ? 82  CYS R O   1 
ATOM 4894 C CB  . CYS E 5 146 ? 154.159 141.942 114.685 1.00 104.93 ? 82  CYS R CB  1 
ATOM 4895 S SG  . CYS E 5 146 ? 155.628 141.699 115.711 1.00 109.89 ? 82  CYS R SG  1 
ATOM 4896 N N   . LEU E 5 147 ? 151.278 143.232 113.938 1.00 115.31 ? 83  LEU R N   1 
ATOM 4897 C CA  . LEU E 5 147 ? 150.213 143.537 112.989 1.00 115.18 ? 83  LEU R CA  1 
ATOM 4898 C C   . LEU E 5 147 ? 150.045 145.042 112.808 1.00 115.17 ? 83  LEU R C   1 
ATOM 4899 O O   . LEU E 5 147 ? 149.808 145.521 111.694 1.00 114.61 ? 83  LEU R O   1 
ATOM 4900 C CB  . LEU E 5 147 ? 148.902 142.902 113.452 1.00 114.57 ? 83  LEU R CB  1 
ATOM 4901 C CG  . LEU E 5 147 ? 148.736 141.398 113.222 1.00 116.90 ? 83  LEU R CG  1 
ATOM 4902 C CD1 . LEU E 5 147 ? 147.470 140.876 113.890 1.00 118.14 ? 83  LEU R CD1 1 
ATOM 4903 C CD2 . LEU E 5 147 ? 148.720 141.088 111.734 1.00 120.71 ? 83  LEU R CD2 1 
ATOM 4904 N N   . ALA E 5 148 ? 150.140 145.802 113.900 1.00 127.17 ? 84  ALA R N   1 
ATOM 4905 C CA  . ALA E 5 148 ? 150.089 147.256 113.801 1.00 128.45 ? 84  ALA R CA  1 
ATOM 4906 C C   . ALA E 5 148 ? 151.273 147.794 113.011 1.00 131.41 ? 84  ALA R C   1 
ATOM 4907 O O   . ALA E 5 148 ? 151.121 148.708 112.195 1.00 132.67 ? 84  ALA R O   1 
ATOM 4908 C CB  . ALA E 5 148 ? 150.049 147.876 115.196 1.00 126.64 ? 84  ALA R CB  1 
ATOM 4909 N N   . ASP E 5 149 ? 152.464 147.245 113.246 1.00 129.30 ? 85  ASP R N   1 
ATOM 4910 C CA  . ASP E 5 149 ? 153.620 147.654 112.457 1.00 125.87 ? 85  ASP R CA  1 
ATOM 4911 C C   . ASP E 5 149 ? 153.454 147.267 110.993 1.00 130.86 ? 85  ASP R C   1 
ATOM 4912 O O   . ASP E 5 149 ? 153.942 147.973 110.105 1.00 132.51 ? 85  ASP R O   1 
ATOM 4913 C CB  . ASP E 5 149 ? 154.895 147.049 113.037 1.00 125.16 ? 85  ASP R CB  1 
ATOM 4914 C CG  . ASP E 5 149 ? 155.148 147.490 114.464 1.00 130.35 ? 85  ASP R CG  1 
ATOM 4915 O OD1 . ASP E 5 149 ? 154.647 148.566 114.851 1.00 135.68 ? 85  ASP R OD1 1 
ATOM 4916 O OD2 . ASP E 5 149 ? 155.846 146.762 115.200 1.00 135.21 ? 85  ASP R OD2 1 
ATOM 4917 N N   . LEU E 5 150 ? 152.750 146.165 110.723 1.00 132.92 ? 86  LEU R N   1 
ATOM 4918 C CA  . LEU E 5 150 ? 152.450 145.784 109.347 1.00 131.32 ? 86  LEU R CA  1 
ATOM 4919 C C   . LEU E 5 150 ? 151.501 146.778 108.696 1.00 133.42 ? 86  LEU R C   1 
ATOM 4920 O O   . LEU E 5 150 ? 151.694 147.164 107.540 1.00 138.17 ? 86  LEU R O   1 
ATOM 4921 C CB  . LEU E 5 150 ? 151.849 144.378 109.306 1.00 129.32 ? 86  LEU R CB  1 
ATOM 4922 C CG  . LEU E 5 150 ? 152.807 143.194 109.438 1.00 134.43 ? 86  LEU R CG  1 
ATOM 4923 C CD1 . LEU E 5 150 ? 152.067 141.877 109.262 1.00 135.06 ? 86  LEU R CD1 1 
ATOM 4924 C CD2 . LEU E 5 150 ? 153.933 143.313 108.429 1.00 133.06 ? 86  LEU R CD2 1 
ATOM 4925 N N   . ALA E 5 151 ? 150.456 147.181 109.416 1.00 137.38 ? 87  ALA R N   1 
ATOM 4926 C CA  . ALA E 5 151 ? 149.555 148.205 108.900 1.00 139.65 ? 87  ALA R CA  1 
ATOM 4927 C C   . ALA E 5 151 ? 150.304 149.508 108.645 1.00 142.08 ? 87  ALA R C   1 
ATOM 4928 O O   . ALA E 5 151 ? 150.081 150.177 107.626 1.00 144.41 ? 87  ALA R O   1 
ATOM 4929 C CB  . ALA E 5 151 ? 148.400 148.424 109.876 1.00 138.41 ? 87  ALA R CB  1 
ATOM 4930 N N   . VAL E 5 152 ? 151.213 149.869 109.555 1.00 137.91 ? 88  VAL R N   1 
ATOM 4931 C CA  . VAL E 5 152 ? 152.050 151.051 109.362 1.00 137.52 ? 88  VAL R CA  1 
ATOM 4932 C C   . VAL E 5 152 ? 152.862 150.921 108.082 1.00 136.62 ? 88  VAL R C   1 
ATOM 4933 O O   . VAL E 5 152 ? 152.865 151.815 107.239 1.00 135.43 ? 88  VAL R O   1 
ATOM 4934 C CB  . VAL E 5 152 ? 152.967 151.265 110.581 1.00 136.31 ? 88  VAL R CB  1 
ATOM 4935 C CG1 . VAL E 5 152 ? 154.050 152.279 110.257 1.00 134.11 ? 88  VAL R CG1 1 
ATOM 4936 C CG2 . VAL E 5 152 ? 152.159 151.727 111.780 1.00 136.40 ? 88  VAL R CG2 1 
ATOM 4937 N N   . ALA E 5 153 ? 153.561 149.799 107.915 1.00 143.49 ? 89  ALA R N   1 
ATOM 4938 C CA  . ALA E 5 153 ? 154.368 149.604 106.714 1.00 147.39 ? 89  ALA R CA  1 
ATOM 4939 C C   . ALA E 5 153 ? 153.514 149.671 105.453 1.00 146.71 ? 89  ALA R C   1 
ATOM 4940 O O   . ALA E 5 153 ? 153.878 150.363 104.484 1.00 146.43 ? 89  ALA R O   1 
ATOM 4941 C CB  . ALA E 5 153 ? 155.103 148.267 106.786 1.00 149.33 ? 89  ALA R CB  1 
ATOM 4942 N N   . LEU E 5 154 ? 152.357 149.014 105.470 1.00 161.45 ? 90  LEU R N   1 
ATOM 4943 C CA  . LEU E 5 154 ? 151.523 148.941 104.283 1.00 162.26 ? 90  LEU R CA  1 
ATOM 4944 C C   . LEU E 5 154 ? 150.840 150.261 103.953 1.00 166.06 ? 90  LEU R C   1 
ATOM 4945 O O   . LEU E 5 154 ? 150.421 150.449 102.807 1.00 168.57 ? 90  LEU R O   1 
ATOM 4946 C CB  . LEU E 5 154 ? 150.469 147.847 104.456 1.00 162.65 ? 90  LEU R CB  1 
ATOM 4947 N N   . PHE E 5 155 ? 150.697 151.174 104.919 1.00 183.10 ? 91  PHE R N   1 
ATOM 4948 C CA  . PHE E 5 155 ? 149.935 152.391 104.659 1.00 184.43 ? 91  PHE R CA  1 
ATOM 4949 C C   . PHE E 5 155 ? 150.649 153.678 105.063 1.00 185.31 ? 91  PHE R C   1 
ATOM 4950 O O   . PHE E 5 155 ? 150.031 154.747 105.019 1.00 187.35 ? 91  PHE R O   1 
ATOM 4951 C CB  . PHE E 5 155 ? 148.567 152.305 105.345 1.00 183.35 ? 91  PHE R CB  1 
ATOM 4952 C CG  . PHE E 5 155 ? 147.620 151.346 104.671 1.00 184.69 ? 91  PHE R CG  1 
ATOM 4953 C CD1 . PHE E 5 155 ? 147.118 151.627 103.411 1.00 184.01 ? 91  PHE R CD1 1 
ATOM 4954 C CD2 . PHE E 5 155 ? 147.238 150.165 105.288 1.00 186.89 ? 91  PHE R CD2 1 
ATOM 4955 C CE1 . PHE E 5 155 ? 146.251 150.754 102.776 1.00 186.14 ? 91  PHE R CE1 1 
ATOM 4956 C CE2 . PHE E 5 155 ? 146.369 149.286 104.657 1.00 187.40 ? 91  PHE R CE2 1 
ATOM 4957 C CZ  . PHE E 5 155 ? 145.876 149.583 103.400 1.00 186.80 ? 91  PHE R CZ  1 
ATOM 4958 N N   . GLN E 5 156 ? 151.916 153.608 105.454 1.00 160.67 ? 92  GLN R N   1 
ATOM 4959 C CA  . GLN E 5 156 ? 152.802 154.755 105.583 1.00 157.27 ? 92  GLN R CA  1 
ATOM 4960 C C   . GLN E 5 156 ? 153.856 154.798 104.493 1.00 157.61 ? 92  GLN R C   1 
ATOM 4961 O O   . GLN E 5 156 ? 154.103 155.867 103.921 1.00 161.09 ? 92  GLN R O   1 
ATOM 4962 C CB  . GLN E 5 156 ? 153.498 154.742 106.953 1.00 158.57 ? 92  GLN R CB  1 
ATOM 4963 C CG  . GLN E 5 156 ? 154.599 155.781 107.127 1.00 160.61 ? 92  GLN R CG  1 
ATOM 4964 C CD  . GLN E 5 156 ? 154.063 157.192 107.310 1.00 160.49 ? 92  GLN R CD  1 
ATOM 4965 O OE1 . GLN E 5 156 ? 154.019 157.712 108.426 1.00 156.93 ? 92  GLN R OE1 1 
ATOM 4966 N NE2 . GLN E 5 156 ? 153.658 157.818 106.213 1.00 160.93 ? 92  GLN R NE2 1 
ATOM 4967 N N   . VAL E 5 157 ? 154.480 153.641 104.180 1.00 158.67 ? 93  VAL R N   1 
ATOM 4968 C CA  . VAL E 5 157 ? 155.562 153.630 103.200 1.00 161.62 ? 93  VAL R CA  1 
ATOM 4969 C C   . VAL E 5 157 ? 155.014 153.498 101.785 1.00 162.31 ? 93  VAL R C   1 
ATOM 4970 O O   . VAL E 5 157 ? 155.454 154.204 100.875 1.00 161.18 ? 93  VAL R O   1 
ATOM 4971 C CB  . VAL E 5 157 ? 156.545 152.490 103.517 1.00 159.37 ? 93  VAL R CB  1 
ATOM 4972 N N   . LEU E 5 158 ? 154.080 152.568 101.575 1.00 172.13 ? 94  LEU R N   1 
ATOM 4973 C CA  . LEU E 5 158 ? 153.487 152.375 100.251 1.00 171.17 ? 94  LEU R CA  1 
ATOM 4974 C C   . LEU E 5 158 ? 152.862 153.641 99.683  1.00 172.90 ? 94  LEU R C   1 
ATOM 4975 O O   . LEU E 5 158 ? 153.102 153.938 98.498  1.00 174.66 ? 94  LEU R O   1 
ATOM 4976 C CB  . LEU E 5 158 ? 152.468 151.232 100.320 1.00 169.56 ? 94  LEU R CB  1 
ATOM 4977 C CG  . LEU E 5 158 ? 151.792 150.702 99.053  1.00 172.23 ? 94  LEU R CG  1 
ATOM 4978 C CD1 . LEU E 5 158 ? 151.437 149.242 99.258  1.00 174.05 ? 94  LEU R CD1 1 
ATOM 4979 C CD2 . LEU E 5 158 ? 150.541 151.494 98.696  1.00 171.64 ? 94  LEU R CD2 1 
ATOM 4980 N N   . PRO E 5 159 ? 152.044 154.403 100.422 1.00 165.95 ? 95  PRO R N   1 
ATOM 4981 C CA  . PRO E 5 159 ? 151.560 155.673 99.859  1.00 164.96 ? 95  PRO R CA  1 
ATOM 4982 C C   . PRO E 5 159 ? 152.711 156.573 99.490  1.00 166.22 ? 95  PRO R C   1 
ATOM 4983 O O   . PRO E 5 159 ? 152.724 157.167 98.404  1.00 167.67 ? 95  PRO R O   1 
ATOM 4984 C CB  . PRO E 5 159 ? 150.710 156.258 101.001 1.00 163.74 ? 95  PRO R CB  1 
ATOM 4985 C CG  . PRO E 5 159 ? 150.336 155.083 101.829 1.00 165.36 ? 95  PRO R CG  1 
ATOM 4986 C CD  . PRO E 5 159 ? 151.533 154.192 101.784 1.00 165.46 ? 95  PRO R CD  1 
ATOM 4987 N N   . GLN E 5 160 ? 153.695 156.679 100.382 1.00 171.75 ? 96  GLN R N   1 
ATOM 4988 C CA  . GLN E 5 160 ? 154.877 157.485 100.108 1.00 171.57 ? 96  GLN R CA  1 
ATOM 4989 C C   . GLN E 5 160 ? 155.597 157.004 98.853  1.00 172.78 ? 96  GLN R C   1 
ATOM 4990 O O   . GLN E 5 160 ? 156.045 157.819 98.042  1.00 171.67 ? 96  GLN R O   1 
ATOM 4991 C CB  . GLN E 5 160 ? 155.813 157.457 101.316 1.00 172.04 ? 96  GLN R CB  1 
ATOM 4992 C CG  . GLN E 5 160 ? 157.071 158.283 101.152 1.00 171.34 ? 96  GLN R CG  1 
ATOM 4993 C CD  . GLN E 5 160 ? 156.803 159.751 100.917 1.00 169.22 ? 96  GLN R CD  1 
ATOM 4994 O OE1 . GLN E 5 160 ? 156.043 160.379 101.651 1.00 167.58 ? 96  GLN R OE1 1 
ATOM 4995 N NE2 . GLN E 5 160 ? 157.436 160.311 99.892  1.00 170.78 ? 96  GLN R NE2 1 
ATOM 4996 N N   . LEU E 5 161 ? 155.718 155.687 98.673  1.00 177.32 ? 97  LEU R N   1 
ATOM 4997 C CA  . LEU E 5 161 ? 156.385 155.152 97.487  1.00 175.75 ? 97  LEU R CA  1 
ATOM 4998 C C   . LEU E 5 161 ? 155.610 155.499 96.221  1.00 174.50 ? 97  LEU R C   1 
ATOM 4999 O O   . LEU E 5 161 ? 156.188 155.954 95.224  1.00 173.84 ? 97  LEU R O   1 
ATOM 5000 C CB  . LEU E 5 161 ? 156.543 153.634 97.626  1.00 176.48 ? 97  LEU R CB  1 
ATOM 5001 C CG  . LEU E 5 161 ? 157.687 152.896 96.916  1.00 175.60 ? 97  LEU R CG  1 
ATOM 5002 C CD1 . LEU E 5 161 ? 157.515 152.870 95.402  1.00 173.80 ? 97  LEU R CD1 1 
ATOM 5003 C CD2 . LEU E 5 161 ? 159.036 153.491 97.292  1.00 175.68 ? 97  LEU R CD2 1 
ATOM 5004 N N   . ALA E 5 162 ? 154.292 155.297 96.250  1.00 197.02 ? 98  ALA R N   1 
ATOM 5005 C CA  . ALA E 5 162 ? 153.460 155.581 95.088  1.00 199.18 ? 98  ALA R CA  1 
ATOM 5006 C C   . ALA E 5 162 ? 153.465 157.064 94.753  1.00 201.38 ? 98  ALA R C   1 
ATOM 5007 O O   . ALA E 5 162 ? 153.373 157.443 93.581  1.00 201.49 ? 98  ALA R O   1 
ATOM 5008 C CB  . ALA E 5 162 ? 152.033 155.095 95.348  1.00 198.28 ? 98  ALA R CB  1 
ATOM 5009 N N   . TRP E 5 163 ? 153.555 157.912 95.774  1.00 220.15 ? 99  TRP R N   1 
ATOM 5010 C CA  . TRP E 5 163 ? 153.604 159.352 95.565  1.00 219.93 ? 99  TRP R CA  1 
ATOM 5011 C C   . TRP E 5 163 ? 154.963 159.783 95.027  1.00 220.25 ? 99  TRP R C   1 
ATOM 5012 O O   . TRP E 5 163 ? 155.042 160.644 94.144  1.00 221.59 ? 99  TRP R O   1 
ATOM 5013 C CB  . TRP E 5 163 ? 153.284 160.051 96.884  1.00 219.71 ? 99  TRP R CB  1 
ATOM 5014 C CG  . TRP E 5 163 ? 152.974 161.508 96.800  1.00 220.92 ? 99  TRP R CG  1 
ATOM 5015 C CD1 . TRP E 5 163 ? 153.590 162.445 96.023  1.00 221.56 ? 99  TRP R CD1 1 
ATOM 5016 C CD2 . TRP E 5 163 ? 151.980 162.203 97.554  1.00 221.29 ? 99  TRP R CD2 1 
ATOM 5017 N NE1 . TRP E 5 163 ? 153.033 163.680 96.241  1.00 222.23 ? 99  TRP R NE1 1 
ATOM 5018 C CE2 . TRP E 5 163 ? 152.043 163.557 97.181  1.00 221.36 ? 99  TRP R CE2 1 
ATOM 5019 C CE3 . TRP E 5 163 ? 151.043 161.810 98.515  1.00 221.07 ? 99  TRP R CE3 1 
ATOM 5020 C CZ2 . TRP E 5 163 ? 151.197 164.511 97.720  1.00 219.86 ? 99  TRP R CZ2 1 
ATOM 5021 C CZ3 . TRP E 5 163 ? 150.211 162.766 99.056  1.00 220.20 ? 99  TRP R CZ3 1 
ATOM 5022 C CH2 . TRP E 5 163 ? 150.296 164.104 98.661  1.00 219.41 ? 99  TRP R CH2 1 
ATOM 5023 N N   . LYS E 5 164 ? 156.043 159.200 95.553  1.00 221.90 ? 100 LYS R N   1 
ATOM 5024 C CA  . LYS E 5 164 ? 157.373 159.496 95.036  1.00 223.34 ? 100 LYS R CA  1 
ATOM 5025 C C   . LYS E 5 164 ? 157.482 159.100 93.572  1.00 224.09 ? 100 LYS R C   1 
ATOM 5026 O O   . LYS E 5 164 ? 158.071 159.829 92.765  1.00 224.52 ? 100 LYS R O   1 
ATOM 5027 C CB  . LYS E 5 164 ? 158.436 158.783 95.874  1.00 223.15 ? 100 LYS R CB  1 
ATOM 5028 N N   . ALA E 5 165 ? 156.928 157.951 93.207  1.00 229.96 ? 101 ALA R N   1 
ATOM 5029 C CA  . ALA E 5 165 ? 156.701 157.688 91.796  1.00 229.73 ? 101 ALA R CA  1 
ATOM 5030 C C   . ALA E 5 165 ? 155.681 158.681 91.256  1.00 231.29 ? 101 ALA R C   1 
ATOM 5031 O O   . ALA E 5 165 ? 154.742 159.071 91.956  1.00 232.13 ? 101 ALA R O   1 
ATOM 5032 C CB  . ALA E 5 165 ? 156.217 156.257 91.581  1.00 228.81 ? 101 ALA R CB  1 
ATOM 5033 N N   . THR E 5 166 ? 155.882 159.102 90.008  1.00 230.77 ? 102 THR R N   1 
ATOM 5034 C CA  . THR E 5 166 ? 155.078 160.137 89.333  1.00 229.81 ? 102 THR R CA  1 
ATOM 5035 C C   . THR E 5 166 ? 155.086 161.377 90.234  1.00 228.71 ? 102 THR R C   1 
ATOM 5036 O O   . THR E 5 166 ? 156.163 161.784 90.686  1.00 227.02 ? 102 THR R O   1 
ATOM 5037 C CB  . THR E 5 166 ? 153.704 159.590 88.962  1.00 228.19 ? 102 THR R CB  1 
ATOM 5038 O OG1 . THR E 5 166 ? 152.932 159.362 90.146  1.00 228.83 ? 102 THR R OG1 1 
ATOM 5039 C CG2 . THR E 5 166 ? 153.838 158.281 88.186  1.00 227.27 ? 102 THR R CG2 1 
ATOM 5040 N N   . ASP E 5 167 ? 153.933 162.003 90.527  1.00 230.17 ? 103 ASP R N   1 
ATOM 5041 C CA  . ASP E 5 167 ? 153.988 163.195 91.366  1.00 229.58 ? 103 ASP R CA  1 
ATOM 5042 C C   . ASP E 5 167 ? 152.869 163.315 92.404  1.00 230.74 ? 103 ASP R C   1 
ATOM 5043 O O   . ASP E 5 167 ? 152.669 164.410 92.939  1.00 230.09 ? 103 ASP R O   1 
ATOM 5044 C CB  . ASP E 5 167 ? 153.996 164.461 90.495  1.00 229.05 ? 103 ASP R CB  1 
ATOM 5045 C CG  . ASP E 5 167 ? 155.385 164.812 89.985  1.00 229.98 ? 103 ASP R CG  1 
ATOM 5046 O OD1 . ASP E 5 167 ? 156.361 164.639 90.744  1.00 229.02 ? 103 ASP R OD1 1 
ATOM 5047 O OD2 . ASP E 5 167 ? 155.503 165.264 88.826  1.00 231.02 ? 103 ASP R OD2 1 
ATOM 5048 N N   . ARG E 5 168 ? 152.151 162.234 92.722  1.00 239.04 ? 104 ARG R N   1 
ATOM 5049 C CA  . ARG E 5 168 ? 151.108 162.255 93.745  1.00 237.52 ? 104 ARG R CA  1 
ATOM 5050 C C   . ARG E 5 168 ? 150.601 160.837 93.937  1.00 238.08 ? 104 ARG R C   1 
ATOM 5051 O O   . ARG E 5 168 ? 150.919 159.936 93.156  1.00 239.34 ? 104 ARG R O   1 
ATOM 5052 C CB  . ARG E 5 168 ? 149.955 163.197 93.374  1.00 237.06 ? 104 ARG R CB  1 
ATOM 5053 C CG  . ARG E 5 168 ? 148.997 162.693 92.293  1.00 237.46 ? 104 ARG R CG  1 
ATOM 5054 C CD  . ARG E 5 168 ? 149.629 162.637 90.901  1.00 237.87 ? 104 ARG R CD  1 
ATOM 5055 N NE  . ARG E 5 168 ? 149.977 161.275 90.509  1.00 239.07 ? 104 ARG R NE  1 
ATOM 5056 C CZ  . ARG E 5 168 ? 150.201 160.889 89.260  1.00 238.77 ? 104 ARG R CZ  1 
ATOM 5057 N NH1 . ARG E 5 168 ? 150.155 161.744 88.252  1.00 239.19 ? 104 ARG R NH1 1 
ATOM 5058 N NH2 . ARG E 5 168 ? 150.456 159.608 89.012  1.00 237.45 ? 104 ARG R NH2 1 
ATOM 5059 N N   . PHE E 5 169 ? 149.800 160.643 94.988  1.00 218.34 ? 105 PHE R N   1 
ATOM 5060 C CA  . PHE E 5 169 ? 149.155 159.352 95.257  1.00 218.64 ? 105 PHE R CA  1 
ATOM 5061 C C   . PHE E 5 169 ? 147.890 159.255 94.408  1.00 218.93 ? 105 PHE R C   1 
ATOM 5062 O O   . PHE E 5 169 ? 146.782 159.588 94.841  1.00 216.86 ? 105 PHE R O   1 
ATOM 5063 C CB  . PHE E 5 169 ? 148.859 159.186 96.743  1.00 217.25 ? 105 PHE R CB  1 
ATOM 5064 N N   . ARG E 5 170 ? 148.069 158.800 93.171  1.00 214.52 ? 106 ARG R N   1 
ATOM 5065 C CA  . ARG E 5 170 ? 146.955 158.652 92.245  1.00 212.59 ? 106 ARG R CA  1 
ATOM 5066 C C   . ARG E 5 170 ? 145.944 157.641 92.768  1.00 211.24 ? 106 ARG R C   1 
ATOM 5067 O O   . ARG E 5 170 ? 146.308 156.551 93.220  1.00 210.15 ? 106 ARG R O   1 
ATOM 5068 C CB  . ARG E 5 170 ? 147.465 158.219 90.871  1.00 211.86 ? 106 ARG R CB  1 
ATOM 5069 N N   . GLY E 5 171 ? 144.672 158.008 92.698  1.00 203.62 ? 107 GLY R N   1 
ATOM 5070 C CA  . GLY E 5 171 ? 143.602 157.136 93.130  1.00 203.15 ? 107 GLY R CA  1 
ATOM 5071 C C   . GLY E 5 171 ? 142.283 157.871 93.215  1.00 203.51 ? 107 GLY R C   1 
ATOM 5072 O O   . GLY E 5 171 ? 142.212 159.084 93.005  1.00 203.58 ? 107 GLY R O   1 
ATOM 5073 N N   . ASP E 5 173 ? 139.113 159.566 95.209  1.00 202.94 ? 109 ASP R N   1 
ATOM 5074 C CA  . ASP E 5 173 ? 139.073 160.387 96.411  1.00 203.49 ? 109 ASP R CA  1 
ATOM 5075 C C   . ASP E 5 173 ? 138.774 159.551 97.660  1.00 203.28 ? 109 ASP R C   1 
ATOM 5076 O O   . ASP E 5 173 ? 139.328 159.809 98.733  1.00 203.63 ? 109 ASP R O   1 
ATOM 5077 C CB  . ASP E 5 173 ? 138.042 161.504 96.245  1.00 203.22 ? 109 ASP R CB  1 
ATOM 5078 N N   . ALA E 5 174 ? 137.910 158.543 97.517  1.00 189.53 ? 110 ALA R N   1 
ATOM 5079 C CA  . ALA E 5 174 ? 137.603 157.680 98.654  1.00 188.70 ? 110 ALA R CA  1 
ATOM 5080 C C   . ALA E 5 174 ? 138.865 157.020 99.187  1.00 189.28 ? 110 ALA R C   1 
ATOM 5081 O O   . ALA E 5 174 ? 139.149 157.079 100.386 1.00 188.83 ? 110 ALA R O   1 
ATOM 5082 C CB  . ALA E 5 174 ? 136.571 156.630 98.255  1.00 188.52 ? 110 ALA R CB  1 
ATOM 5083 N N   . LEU E 5 175 ? 139.661 156.426 98.293  1.00 190.08 ? 111 LEU R N   1 
ATOM 5084 C CA  . LEU E 5 175 ? 140.930 155.830 98.697  1.00 189.73 ? 111 LEU R CA  1 
ATOM 5085 C C   . LEU E 5 175 ? 141.923 156.896 99.134  1.00 189.88 ? 111 LEU R C   1 
ATOM 5086 O O   . LEU E 5 175 ? 142.734 156.660 100.038 1.00 188.35 ? 111 LEU R O   1 
ATOM 5087 C CB  . LEU E 5 175 ? 141.503 155.001 97.545  1.00 190.33 ? 111 LEU R CB  1 
ATOM 5088 N N   . CYS E 5 176 ? 141.864 158.070 98.504  1.00 210.47 ? 112 CYS R N   1 
ATOM 5089 C CA  . CYS E 5 176 ? 142.738 159.180 98.865  1.00 211.93 ? 112 CYS R CA  1 
ATOM 5090 C C   . CYS E 5 176 ? 142.635 159.502 100.352 1.00 212.83 ? 112 CYS R C   1 
ATOM 5091 O O   . CYS E 5 176 ? 143.652 159.667 101.034 1.00 212.86 ? 112 CYS R O   1 
ATOM 5092 C CB  . CYS E 5 176 ? 142.375 160.396 98.008  1.00 211.77 ? 112 CYS R CB  1 
ATOM 5093 S SG  . CYS E 5 176 ? 143.454 161.852 98.059  1.00 217.19 ? 112 CYS R SG  1 
ATOM 5094 N N   . ARG E 5 177 ? 141.407 159.586 100.878 1.00 201.25 ? 113 ARG R N   1 
ATOM 5095 C CA  . ARG E 5 177 ? 141.236 159.805 102.313 1.00 199.22 ? 113 ARG R CA  1 
ATOM 5096 C C   . ARG E 5 177 ? 141.333 158.510 103.120 1.00 198.29 ? 113 ARG R C   1 
ATOM 5097 O O   . ARG E 5 177 ? 141.700 158.546 104.302 1.00 198.40 ? 113 ARG R O   1 
ATOM 5098 C CB  . ARG E 5 177 ? 139.898 160.498 102.587 1.00 197.17 ? 113 ARG R CB  1 
ATOM 5099 N N   . ALA E 5 178 ? 140.998 157.370 102.510 1.00 177.16 ? 114 ALA R N   1 
ATOM 5100 C CA  . ALA E 5 178 ? 141.059 156.097 103.222 1.00 175.65 ? 114 ALA R CA  1 
ATOM 5101 C C   . ALA E 5 178 ? 142.483 155.783 103.642 1.00 176.43 ? 114 ALA R C   1 
ATOM 5102 O O   . ALA E 5 178 ? 142.720 155.224 104.721 1.00 174.59 ? 114 ALA R O   1 
ATOM 5103 C CB  . ALA E 5 178 ? 140.504 154.979 102.337 1.00 177.28 ? 114 ALA R CB  1 
ATOM 5104 N N   . VAL E 5 179 ? 143.440 156.105 102.780 1.00 178.79 ? 115 VAL R N   1 
ATOM 5105 C CA  . VAL E 5 179 ? 144.840 155.933 103.128 1.00 178.68 ? 115 VAL R CA  1 
ATOM 5106 C C   . VAL E 5 179 ? 145.159 156.700 104.403 1.00 178.51 ? 115 VAL R C   1 
ATOM 5107 O O   . VAL E 5 179 ? 145.805 156.176 105.316 1.00 180.29 ? 115 VAL R O   1 
ATOM 5108 C CB  . VAL E 5 179 ? 145.735 156.377 101.959 1.00 177.50 ? 115 VAL R CB  1 
ATOM 5109 N N   . LYS E 5 180 ? 144.711 157.954 104.481 1.00 171.14 ? 116 LYS R N   1 
ATOM 5110 C CA  . LYS E 5 180 ? 144.964 158.758 105.670 1.00 171.82 ? 116 LYS R CA  1 
ATOM 5111 C C   . LYS E 5 180 ? 144.363 158.106 106.904 1.00 170.54 ? 116 LYS R C   1 
ATOM 5112 O O   . LYS E 5 180 ? 145.021 157.990 107.947 1.00 169.44 ? 116 LYS R O   1 
ATOM 5113 C CB  . LYS E 5 180 ? 144.400 160.164 105.469 1.00 173.65 ? 116 LYS R CB  1 
ATOM 5114 C CG  . LYS E 5 180 ? 145.132 160.917 104.391 1.00 173.56 ? 116 LYS R CG  1 
ATOM 5115 C CD  . LYS E 5 180 ? 146.546 161.246 104.831 1.00 173.90 ? 116 LYS R CD  1 
ATOM 5116 C CE  . LYS E 5 180 ? 147.325 161.844 103.680 1.00 172.29 ? 116 LYS R CE  1 
ATOM 5117 N NZ  . LYS E 5 180 ? 148.675 162.308 104.087 1.00 171.90 ? 116 LYS R NZ  1 
ATOM 5118 N N   . TYR E 5 181 ? 143.100 157.686 106.803 1.00 159.26 ? 117 TYR R N   1 
ATOM 5119 C CA  . TYR E 5 181 ? 142.461 156.987 107.911 1.00 157.83 ? 117 TYR R CA  1 
ATOM 5120 C C   . TYR E 5 181 ? 143.302 155.806 108.380 1.00 157.63 ? 117 TYR R C   1 
ATOM 5121 O O   . TYR E 5 181 ? 143.602 155.679 109.572 1.00 159.00 ? 117 TYR R O   1 
ATOM 5122 C CB  . TYR E 5 181 ? 141.059 156.520 107.507 1.00 159.08 ? 117 TYR R CB  1 
ATOM 5123 C CG  . TYR E 5 181 ? 140.482 155.507 108.470 1.00 162.43 ? 117 TYR R CG  1 
ATOM 5124 C CD1 . TYR E 5 181 ? 140.035 155.890 109.727 1.00 161.49 ? 117 TYR R CD1 1 
ATOM 5125 C CD2 . TYR E 5 181 ? 140.402 154.165 108.128 1.00 164.54 ? 117 TYR R CD2 1 
ATOM 5126 C CE1 . TYR E 5 181 ? 139.518 154.967 110.613 1.00 162.22 ? 117 TYR R CE1 1 
ATOM 5127 C CE2 . TYR E 5 181 ? 139.887 153.235 109.006 1.00 162.48 ? 117 TYR R CE2 1 
ATOM 5128 C CZ  . TYR E 5 181 ? 139.446 153.640 110.245 1.00 162.80 ? 117 TYR R CZ  1 
ATOM 5129 O OH  . TYR E 5 181 ? 138.932 152.709 111.114 1.00 163.49 ? 117 TYR R OH  1 
ATOM 5130 N N   . LEU E 5 182 ? 143.717 154.941 107.452 1.00 158.13 ? 118 LEU R N   1 
ATOM 5131 C CA  . LEU E 5 182 ? 144.439 153.733 107.843 1.00 161.56 ? 118 LEU R CA  1 
ATOM 5132 C C   . LEU E 5 182 ? 145.802 154.072 108.411 1.00 160.53 ? 118 LEU R C   1 
ATOM 5133 O O   . LEU E 5 182 ? 146.274 153.416 109.360 1.00 162.38 ? 118 LEU R O   1 
ATOM 5134 C CB  . LEU E 5 182 ? 144.560 152.799 106.641 1.00 161.39 ? 118 LEU R CB  1 
ATOM 5135 C CG  . LEU E 5 182 ? 143.191 152.350 106.122 1.00 161.38 ? 118 LEU R CG  1 
ATOM 5136 C CD1 . LEU E 5 182 ? 143.315 151.708 104.758 1.00 161.56 ? 118 LEU R CD1 1 
ATOM 5137 C CD2 . LEU E 5 182 ? 142.514 151.399 107.100 1.00 161.88 ? 118 LEU R CD2 1 
ATOM 5138 N N   . GLN E 5 183 ? 146.424 155.115 107.874 1.00 144.01 ? 119 GLN R N   1 
ATOM 5139 C CA  . GLN E 5 183 ? 147.732 155.528 108.292 1.00 144.37 ? 119 GLN R CA  1 
ATOM 5140 C C   . GLN E 5 183 ? 147.694 155.955 109.735 1.00 147.05 ? 119 GLN R C   1 
ATOM 5141 O O   . GLN E 5 183 ? 148.492 155.514 110.574 1.00 147.77 ? 119 GLN R O   1 
ATOM 5142 C CB  . GLN E 5 183 ? 148.181 156.672 107.391 1.00 146.97 ? 119 GLN R CB  1 
ATOM 5143 C CG  . GLN E 5 183 ? 149.663 156.962 107.333 1.00 148.74 ? 119 GLN R CG  1 
ATOM 5144 C CD  . GLN E 5 183 ? 150.014 157.846 106.151 1.00 148.69 ? 119 GLN R CD  1 
ATOM 5145 O OE1 . GLN E 5 183 ? 149.469 158.938 105.990 1.00 147.23 ? 119 GLN R OE1 1 
ATOM 5146 N NE2 . GLN E 5 183 ? 150.898 157.357 105.296 1.00 147.86 ? 119 GLN R NE2 1 
ATOM 5147 N N   . MET E 5 184 ? 146.709 156.816 110.044 1.00 147.57 ? 120 MET R N   1 
ATOM 5148 C CA  . MET E 5 184 ? 146.507 157.280 111.402 1.00 147.55 ? 120 MET R CA  1 
ATOM 5149 C C   . MET E 5 184 ? 146.120 156.130 112.319 1.00 145.77 ? 120 MET R C   1 
ATOM 5150 O O   . MET E 5 184 ? 146.492 156.127 113.499 1.00 145.20 ? 120 MET R O   1 
ATOM 5151 C CB  . MET E 5 184 ? 145.447 158.383 111.428 1.00 146.87 ? 120 MET R CB  1 
ATOM 5152 C CG  . MET E 5 184 ? 146.013 159.749 111.094 1.00 143.86 ? 120 MET R CG  1 
ATOM 5153 S SD  . MET E 5 184 ? 147.491 160.130 112.056 1.00 158.24 ? 120 MET R SD  1 
ATOM 5154 C CE  . MET E 5 184 ? 146.820 160.170 113.716 1.00 147.33 ? 120 MET R CE  1 
ATOM 5155 N N   . VAL E 5 185 ? 145.371 155.154 111.801 1.00 143.60 ? 121 VAL R N   1 
ATOM 5156 C CA  . VAL E 5 185 ? 145.066 153.958 112.581 1.00 145.74 ? 121 VAL R CA  1 
ATOM 5157 C C   . VAL E 5 185 ? 146.358 153.308 113.046 1.00 145.61 ? 121 VAL R C   1 
ATOM 5158 O O   . VAL E 5 185 ? 146.530 152.982 114.227 1.00 148.10 ? 121 VAL R O   1 
ATOM 5159 C CB  . VAL E 5 185 ? 144.211 152.977 111.757 1.00 148.37 ? 121 VAL R CB  1 
ATOM 5160 C CG1 . VAL E 5 185 ? 144.172 151.620 112.430 1.00 147.00 ? 121 VAL R CG1 1 
ATOM 5161 C CG2 . VAL E 5 185 ? 142.802 153.503 111.586 1.00 147.39 ? 121 VAL R CG2 1 
ATOM 5162 N N   . GLY E 5 186 ? 147.298 153.141 112.122 1.00 123.25 ? 122 GLY R N   1 
ATOM 5163 C CA  . GLY E 5 186 ? 148.586 152.592 112.491 1.00 125.08 ? 122 GLY R CA  1 
ATOM 5164 C C   . GLY E 5 186 ? 149.353 153.486 113.443 1.00 121.67 ? 122 GLY R C   1 
ATOM 5165 O O   . GLY E 5 186 ? 150.047 153.001 114.337 1.00 119.35 ? 122 GLY R O   1 
ATOM 5166 N N   . MET E 5 187 ? 149.238 154.805 113.267 1.00 116.32 ? 123 MET R N   1 
ATOM 5167 C CA  . MET E 5 187 ? 149.977 155.729 114.122 1.00 116.88 ? 123 MET R CA  1 
ATOM 5168 C C   . MET E 5 187 ? 149.494 155.651 115.565 1.00 116.35 ? 123 MET R C   1 
ATOM 5169 O O   . MET E 5 187 ? 150.296 155.742 116.503 1.00 112.65 ? 123 MET R O   1 
ATOM 5170 C CB  . MET E 5 187 ? 149.853 157.151 113.581 1.00 116.71 ? 123 MET R CB  1 
ATOM 5171 C CG  . MET E 5 187 ? 150.968 158.074 114.024 1.00 122.31 ? 123 MET R CG  1 
ATOM 5172 S SD  . MET E 5 187 ? 150.943 159.642 113.141 1.00 125.51 ? 123 MET R SD  1 
ATOM 5173 C CE  . MET E 5 187 ? 151.266 159.086 111.469 1.00 121.10 ? 123 MET R CE  1 
ATOM 5174 N N   . TYR E 5 188 ? 148.184 155.492 115.764 1.00 132.28 ? 124 TYR R N   1 
ATOM 5175 C CA  . TYR E 5 188 ? 147.661 155.304 117.113 1.00 134.77 ? 124 TYR R CA  1 
ATOM 5176 C C   . TYR E 5 188 ? 148.043 153.941 117.666 1.00 132.48 ? 124 TYR R C   1 
ATOM 5177 O O   . TYR E 5 188 ? 148.462 153.827 118.824 1.00 133.03 ? 124 TYR R O   1 
ATOM 5178 C CB  . TYR E 5 188 ? 146.141 155.445 117.129 1.00 138.13 ? 124 TYR R CB  1 
ATOM 5179 C CG  . TYR E 5 188 ? 145.595 156.841 116.971 1.00 138.29 ? 124 TYR R CG  1 
ATOM 5180 C CD1 . TYR E 5 188 ? 145.658 157.754 118.010 1.00 132.96 ? 124 TYR R CD1 1 
ATOM 5181 C CD2 . TYR E 5 188 ? 144.971 157.230 115.798 1.00 138.13 ? 124 TYR R CD2 1 
ATOM 5182 C CE1 . TYR E 5 188 ? 145.145 159.020 117.871 1.00 131.76 ? 124 TYR R CE1 1 
ATOM 5183 C CE2 . TYR E 5 188 ? 144.456 158.494 115.650 1.00 134.83 ? 124 TYR R CE2 1 
ATOM 5184 C CZ  . TYR E 5 188 ? 144.547 159.387 116.690 1.00 133.65 ? 124 TYR R CZ  1 
ATOM 5185 O OH  . TYR E 5 188 ? 144.034 160.655 116.552 1.00 139.25 ? 124 TYR R OH  1 
ATOM 5186 N N   . ALA E 5 189 ? 147.913 152.894 116.846 1.00 124.78 ? 125 ALA R N   1 
ATOM 5187 C CA  . ALA E 5 189 ? 148.193 151.543 117.317 1.00 127.45 ? 125 ALA R CA  1 
ATOM 5188 C C   . ALA E 5 189 ? 149.650 151.377 117.722 1.00 126.61 ? 125 ALA R C   1 
ATOM 5189 O O   . ALA E 5 189 ? 149.947 150.642 118.672 1.00 129.04 ? 125 ALA R O   1 
ATOM 5190 C CB  . ALA E 5 189 ? 147.817 150.526 116.241 1.00 130.88 ? 125 ALA R CB  1 
ATOM 5191 N N   . SER E 5 190 ? 150.566 152.074 117.040 1.00 123.53 ? 126 SER R N   1 
ATOM 5192 C CA  . SER E 5 190 ? 151.993 151.932 117.307 1.00 125.27 ? 126 SER R CA  1 
ATOM 5193 C C   . SER E 5 190 ? 152.363 152.289 118.740 1.00 122.88 ? 126 SER R C   1 
ATOM 5194 O O   . SER E 5 190 ? 153.428 151.876 119.208 1.00 126.10 ? 126 SER R O   1 
ATOM 5195 C CB  . SER E 5 190 ? 152.798 152.800 116.339 1.00 126.18 ? 126 SER R CB  1 
ATOM 5196 O OG  . SER E 5 190 ? 152.684 152.331 115.006 1.00 124.81 ? 126 SER R OG  1 
ATOM 5197 N N   . SER E 5 191 ? 151.536 153.065 119.436 1.00 101.22 ? 127 SER R N   1 
ATOM 5198 C CA  . SER E 5 191 ? 151.723 153.298 120.862 1.00 101.17 ? 127 SER R CA  1 
ATOM 5199 C C   . SER E 5 191 ? 150.675 152.619 121.724 1.00 99.00  ? 127 SER R C   1 
ATOM 5200 O O   . SER E 5 191 ? 150.958 152.294 122.879 1.00 108.16 ? 127 SER R O   1 
ATOM 5201 C CB  . SER E 5 191 ? 151.711 154.799 121.168 1.00 105.09 ? 127 SER R CB  1 
ATOM 5202 O OG  . SER E 5 191 ? 150.489 155.392 120.769 1.00 113.65 ? 127 SER R OG  1 
ATOM 5203 N N   . TYR E 5 192 ? 149.476 152.389 121.187 1.00 101.58 ? 128 TYR R N   1 
ATOM 5204 C CA  . TYR E 5 192 ? 148.429 151.756 121.979 1.00 112.95 ? 128 TYR R CA  1 
ATOM 5205 C C   . TYR E 5 192 ? 148.753 150.297 122.274 1.00 114.95 ? 128 TYR R C   1 
ATOM 5206 O O   . TYR E 5 192 ? 148.415 149.793 123.351 1.00 113.60 ? 128 TYR R O   1 
ATOM 5207 C CB  . TYR E 5 192 ? 147.085 151.898 121.267 1.00 115.87 ? 128 TYR R CB  1 
ATOM 5208 C CG  . TYR E 5 192 ? 146.568 153.316 121.314 1.00 117.87 ? 128 TYR R CG  1 
ATOM 5209 C CD1 . TYR E 5 192 ? 147.092 154.224 122.223 1.00 117.97 ? 128 TYR R CD1 1 
ATOM 5210 C CD2 . TYR E 5 192 ? 145.565 153.749 120.459 1.00 118.60 ? 128 TYR R CD2 1 
ATOM 5211 C CE1 . TYR E 5 192 ? 146.636 155.521 122.283 1.00 117.53 ? 128 TYR R CE1 1 
ATOM 5212 C CE2 . TYR E 5 192 ? 145.100 155.053 120.512 1.00 116.18 ? 128 TYR R CE2 1 
ATOM 5213 C CZ  . TYR E 5 192 ? 145.641 155.933 121.427 1.00 116.14 ? 128 TYR R CZ  1 
ATOM 5214 O OH  . TYR E 5 192 ? 145.190 157.231 121.492 1.00 121.11 ? 128 TYR R OH  1 
ATOM 5215 N N   . MET E 5 193 ? 149.412 149.605 121.347 1.00 109.59 ? 129 MET R N   1 
ATOM 5216 C CA  . MET E 5 193 ? 149.831 148.241 121.643 1.00 103.76 ? 129 MET R CA  1 
ATOM 5217 C C   . MET E 5 193 ? 150.912 148.216 122.715 1.00 101.08 ? 129 MET R C   1 
ATOM 5218 O O   . MET E 5 193 ? 150.941 147.298 123.542 1.00 103.69 ? 129 MET R O   1 
ATOM 5219 C CB  . MET E 5 193 ? 150.308 147.545 120.370 1.00 108.83 ? 129 MET R CB  1 
ATOM 5220 N N   . ILE E 5 194 ? 151.787 149.222 122.741 1.00 87.74  ? 130 ILE R N   1 
ATOM 5221 C CA  . ILE E 5 194 ? 152.777 149.283 123.809 1.00 83.75  ? 130 ILE R CA  1 
ATOM 5222 C C   . ILE E 5 194 ? 152.096 149.544 125.143 1.00 89.88  ? 130 ILE R C   1 
ATOM 5223 O O   . ILE E 5 194 ? 152.473 148.972 126.173 1.00 94.72  ? 130 ILE R O   1 
ATOM 5224 C CB  . ILE E 5 194 ? 153.841 150.347 123.499 1.00 78.17  ? 130 ILE R CB  1 
ATOM 5225 C CG1 . ILE E 5 194 ? 154.158 150.357 122.008 1.00 87.86  ? 130 ILE R CG1 1 
ATOM 5226 C CG2 . ILE E 5 194 ? 155.110 150.052 124.261 1.00 73.40  ? 130 ILE R CG2 1 
ATOM 5227 C CD1 . ILE E 5 194 ? 155.317 151.260 121.643 1.00 88.05  ? 130 ILE R CD1 1 
ATOM 5228 N N   . LEU E 5 195 ? 151.082 150.412 125.148 1.00 89.80  ? 131 LEU R N   1 
ATOM 5229 C CA  . LEU E 5 195 ? 150.323 150.645 126.371 1.00 85.92  ? 131 LEU R CA  1 
ATOM 5230 C C   . LEU E 5 195 ? 149.635 149.370 126.839 1.00 90.32  ? 131 LEU R C   1 
ATOM 5231 O O   . LEU E 5 195 ? 149.612 149.071 128.039 1.00 94.54  ? 131 LEU R O   1 
ATOM 5232 C CB  . LEU E 5 195 ? 149.299 151.758 126.157 1.00 79.56  ? 131 LEU R CB  1 
ATOM 5233 C CG  . LEU E 5 195 ? 148.664 152.290 127.442 1.00 77.22  ? 131 LEU R CG  1 
ATOM 5234 C CD1 . LEU E 5 195 ? 149.739 152.831 128.365 1.00 85.38  ? 131 LEU R CD1 1 
ATOM 5235 C CD2 . LEU E 5 195 ? 147.632 153.362 127.134 1.00 85.48  ? 131 LEU R CD2 1 
ATOM 5236 N N   . ALA E 5 196 ? 149.069 148.606 125.904 1.00 101.23 ? 132 ALA R N   1 
ATOM 5237 C CA  . ALA E 5 196 ? 148.460 147.329 126.257 1.00 103.41 ? 132 ALA R CA  1 
ATOM 5238 C C   . ALA E 5 196 ? 149.483 146.381 126.867 1.00 101.42 ? 132 ALA R C   1 
ATOM 5239 O O   . ALA E 5 196 ? 149.198 145.703 127.862 1.00 100.88 ? 132 ALA R O   1 
ATOM 5240 C CB  . ALA E 5 196 ? 147.819 146.697 125.022 1.00 103.96 ? 132 ALA R CB  1 
ATOM 5241 N N   . MET E 5 197 ? 150.682 146.318 126.285 1.00 105.06 ? 133 MET R N   1 
ATOM 5242 C CA  . MET E 5 197 ? 151.710 145.444 126.834 1.00 105.10 ? 133 MET R CA  1 
ATOM 5243 C C   . MET E 5 197 ? 152.098 145.868 128.241 1.00 101.67 ? 133 MET R C   1 
ATOM 5244 O O   . MET E 5 197 ? 152.265 145.022 129.124 1.00 108.17 ? 133 MET R O   1 
ATOM 5245 C CB  . MET E 5 197 ? 152.939 145.427 125.928 1.00 105.96 ? 133 MET R CB  1 
ATOM 5246 N N   . THR E 5 198 ? 152.244 147.174 128.473 1.00 87.47  ? 134 THR R N   1 
ATOM 5247 C CA  . THR E 5 198 ? 152.601 147.641 129.809 1.00 93.19  ? 134 THR R CA  1 
ATOM 5248 C C   . THR E 5 198 ? 151.499 147.330 130.815 1.00 97.98  ? 134 THR R C   1 
ATOM 5249 O O   . THR E 5 198 ? 151.779 146.941 131.954 1.00 96.54  ? 134 THR R O   1 
ATOM 5250 C CB  . THR E 5 198 ? 152.912 149.137 129.784 1.00 96.16  ? 134 THR R CB  1 
ATOM 5251 O OG1 . THR E 5 198 ? 154.038 149.371 128.932 1.00 102.23 ? 134 THR R OG1 1 
ATOM 5252 C CG2 . THR E 5 198 ? 153.245 149.636 131.179 1.00 93.31  ? 134 THR R CG2 1 
ATOM 5253 N N   . LEU E 5 199 ? 150.237 147.482 130.409 1.00 100.77 ? 135 LEU R N   1 
ATOM 5254 C CA  . LEU E 5 199 ? 149.137 147.109 131.293 1.00 95.46  ? 135 LEU R CA  1 
ATOM 5255 C C   . LEU E 5 199 ? 149.191 145.626 131.634 1.00 98.75  ? 135 LEU R C   1 
ATOM 5256 O O   . LEU E 5 199 ? 148.972 145.239 132.787 1.00 99.29  ? 135 LEU R O   1 
ATOM 5257 C CB  . LEU E 5 199 ? 147.795 147.460 130.650 1.00 99.09  ? 135 LEU R CB  1 
ATOM 5258 N N   . ASP E 5 200 ? 149.484 144.781 130.648 1.00 110.20 ? 136 ASP R N   1 
ATOM 5259 C CA  . ASP E 5 200 ? 149.530 143.349 130.915 1.00 108.89 ? 136 ASP R CA  1 
ATOM 5260 C C   . ASP E 5 200 ? 150.692 142.998 131.834 1.00 108.43 ? 136 ASP R C   1 
ATOM 5261 O O   . ASP E 5 200 ? 150.573 142.108 132.683 1.00 106.71 ? 136 ASP R O   1 
ATOM 5262 C CB  . ASP E 5 200 ? 149.622 142.568 129.607 1.00 112.96 ? 136 ASP R CB  1 
ATOM 5263 C CG  . ASP E 5 200 ? 149.240 141.114 129.775 1.00 118.46 ? 136 ASP R CG  1 
ATOM 5264 O OD1 . ASP E 5 200 ? 148.041 140.835 129.980 1.00 119.93 ? 136 ASP R OD1 1 
ATOM 5265 O OD2 . ASP E 5 200 ? 150.137 140.248 129.704 1.00 118.18 ? 136 ASP R OD2 1 
ATOM 5266 N N   . ARG E 5 201 ? 151.827 143.679 131.676 1.00 102.99 ? 137 ARG R N   1 
ATOM 5267 C CA  . ARG E 5 201 ? 152.945 143.444 132.582 1.00 100.04 ? 137 ARG R CA  1 
ATOM 5268 C C   . ARG E 5 201 ? 152.603 143.883 134.000 1.00 104.02 ? 137 ARG R C   1 
ATOM 5269 O O   . ARG E 5 201 ? 153.010 143.236 134.972 1.00 108.51 ? 137 ARG R O   1 
ATOM 5270 C CB  . ARG E 5 201 ? 154.192 144.163 132.075 1.00 98.11  ? 137 ARG R CB  1 
ATOM 5271 C CG  . ARG E 5 201 ? 154.589 143.809 130.651 1.00 104.03 ? 137 ARG R CG  1 
ATOM 5272 C CD  . ARG E 5 201 ? 155.339 142.494 130.551 1.00 96.43  ? 137 ARG R CD  1 
ATOM 5273 N NE  . ARG E 5 201 ? 154.559 141.337 130.974 1.00 95.70  ? 137 ARG R NE  1 
ATOM 5274 C CZ  . ARG E 5 201 ? 153.659 140.720 130.220 1.00 104.06 ? 137 ARG R CZ  1 
ATOM 5275 N NH1 . ARG E 5 201 ? 153.384 141.133 128.994 1.00 107.33 ? 137 ARG R NH1 1 
ATOM 5276 N NH2 . ARG E 5 201 ? 153.018 139.664 130.709 1.00 107.26 ? 137 ARG R NH2 1 
ATOM 5277 N N   . HIS E 5 202 ? 151.860 144.985 134.136 1.00 114.27 ? 138 HIS R N   1 
ATOM 5278 C CA  . HIS E 5 202 ? 151.332 145.373 135.440 1.00 118.86 ? 138 HIS R CA  1 
ATOM 5279 C C   . HIS E 5 202 ? 150.465 144.265 136.022 1.00 122.11 ? 138 HIS R C   1 
ATOM 5280 O O   . HIS E 5 202 ? 150.605 143.896 137.194 1.00 120.22 ? 138 HIS R O   1 
ATOM 5281 C CB  . HIS E 5 202 ? 150.536 146.677 135.309 1.00 116.92 ? 138 HIS R CB  1 
ATOM 5282 C CG  . HIS E 5 202 ? 149.557 146.918 136.420 1.00 117.77 ? 138 HIS R CG  1 
ATOM 5283 N ND1 . HIS E 5 202 ? 149.945 147.238 137.703 1.00 118.94 ? 138 HIS R ND1 1 
ATOM 5284 C CD2 . HIS E 5 202 ? 148.202 146.906 136.431 1.00 116.44 ? 138 HIS R CD2 1 
ATOM 5285 C CE1 . HIS E 5 202 ? 148.873 147.402 138.458 1.00 119.49 ? 138 HIS R CE1 1 
ATOM 5286 N NE2 . HIS E 5 202 ? 147.803 147.204 137.711 1.00 120.32 ? 138 HIS R NE2 1 
ATOM 5287 N N   . ARG E 5 203 ? 149.573 143.709 135.204 1.00 132.43 ? 139 ARG R N   1 
ATOM 5288 C CA  . ARG E 5 203 ? 148.674 142.668 135.685 1.00 130.56 ? 139 ARG R CA  1 
ATOM 5289 C C   . ARG E 5 203 ? 149.428 141.416 136.092 1.00 129.59 ? 139 ARG R C   1 
ATOM 5290 O O   . ARG E 5 203 ? 149.022 140.731 137.034 1.00 132.81 ? 139 ARG R O   1 
ATOM 5291 C CB  . ARG E 5 203 ? 147.645 142.325 134.610 1.00 131.54 ? 139 ARG R CB  1 
ATOM 5292 C CG  . ARG E 5 203 ? 146.792 143.490 134.178 1.00 131.40 ? 139 ARG R CG  1 
ATOM 5293 C CD  . ARG E 5 203 ? 145.786 143.038 133.155 1.00 133.03 ? 139 ARG R CD  1 
ATOM 5294 N NE  . ARG E 5 203 ? 144.963 141.954 133.671 1.00 135.31 ? 139 ARG R NE  1 
ATOM 5295 C CZ  . ARG E 5 203 ? 143.959 141.396 133.009 1.00 134.50 ? 139 ARG R CZ  1 
ATOM 5296 N NH1 . ARG E 5 203 ? 143.625 141.797 131.794 1.00 132.91 ? 139 ARG R NH1 1 
ATOM 5297 N NH2 . ARG E 5 203 ? 143.270 140.414 133.583 1.00 132.97 ? 139 ARG R NH2 1 
ATOM 5298 N N   . ALA E 5 204 ? 150.514 141.093 135.394 1.00 124.74 ? 140 ALA R N   1 
ATOM 5299 C CA  . ALA E 5 204 ? 151.230 139.849 135.653 1.00 126.11 ? 140 ALA R CA  1 
ATOM 5300 C C   . ALA E 5 204 ? 151.751 139.759 137.081 1.00 125.93 ? 140 ALA R C   1 
ATOM 5301 O O   . ALA E 5 204 ? 151.999 138.651 137.570 1.00 131.37 ? 140 ALA R O   1 
ATOM 5302 C CB  . ALA E 5 204 ? 152.388 139.696 134.665 1.00 126.51 ? 140 ALA R CB  1 
ATOM 5303 N N   . ILE E 5 205 ? 151.914 140.897 137.758 1.00 103.49 ? 141 ILE R N   1 
ATOM 5304 C CA  . ILE E 5 205 ? 152.319 140.940 139.162 1.00 107.03 ? 141 ILE R CA  1 
ATOM 5305 C C   . ILE E 5 205 ? 151.163 141.434 140.026 1.00 112.67 ? 141 ILE R C   1 
ATOM 5306 O O   . ILE E 5 205 ? 151.372 142.019 141.096 1.00 112.11 ? 141 ILE R O   1 
ATOM 5307 C CB  . ILE E 5 205 ? 153.568 141.822 139.345 1.00 102.82 ? 141 ILE R CB  1 
ATOM 5308 N N   . CYS E 5 206 ? 149.943 141.170 139.580 1.00 141.08 ? 142 CYS R N   1 
ATOM 5309 C CA  . CYS E 5 206 ? 148.721 141.613 140.232 1.00 143.02 ? 142 CYS R CA  1 
ATOM 5310 C C   . CYS E 5 206 ? 147.761 140.434 140.172 1.00 142.26 ? 142 CYS R C   1 
ATOM 5311 O O   . CYS E 5 206 ? 148.179 139.284 139.993 1.00 139.60 ? 142 CYS R O   1 
ATOM 5312 C CB  . CYS E 5 206 ? 148.174 142.885 139.566 1.00 139.75 ? 142 CYS R CB  1 
ATOM 5313 S SG  . CYS E 5 206 ? 149.057 144.394 140.023 1.00 141.44 ? 142 CYS R SG  1 
ATOM 5314 N N   . ARG E 5 207 ? 146.481 140.706 140.375 1.00 169.04 ? 143 ARG R N   1 
ATOM 5315 C CA  . ARG E 5 207 ? 145.458 139.681 140.241 1.00 167.91 ? 143 ARG R CA  1 
ATOM 5316 C C   . ARG E 5 207 ? 145.669 138.894 138.947 1.00 170.25 ? 143 ARG R C   1 
ATOM 5317 O O   . ARG E 5 207 ? 146.034 139.477 137.919 1.00 171.42 ? 143 ARG R O   1 
ATOM 5318 C CB  . ARG E 5 207 ? 144.073 140.331 140.254 1.00 170.48 ? 143 ARG R CB  1 
ATOM 5319 N N   . PRO E 5 208 ? 145.464 137.573 138.959 1.00 210.37 ? 144 PRO R N   1 
ATOM 5320 C CA  . PRO E 5 208 ? 145.797 136.690 137.840 1.00 212.53 ? 144 PRO R CA  1 
ATOM 5321 C C   . PRO E 5 208 ? 145.170 137.107 136.521 1.00 212.68 ? 144 PRO R C   1 
ATOM 5322 O O   . PRO E 5 208 ? 144.538 136.263 135.889 1.00 212.83 ? 144 PRO R O   1 
ATOM 5323 C CB  . PRO E 5 208 ? 145.240 135.336 138.290 1.00 212.83 ? 144 PRO R CB  1 
ATOM 5324 C CG  . PRO E 5 208 ? 144.260 135.651 139.355 1.00 211.68 ? 144 PRO R CG  1 
ATOM 5325 C CD  . PRO E 5 208 ? 144.813 136.839 140.052 1.00 209.64 ? 144 PRO R CD  1 
ATOM 5326 N N   . ASN E 5 221 ? 142.878 139.197 122.692 1.00 138.50 ? 157 ASN R N   1 
ATOM 5327 C CA  . ASN E 5 221 ? 142.163 139.349 123.953 1.00 141.92 ? 157 ASN R CA  1 
ATOM 5328 C C   . ASN E 5 221 ? 141.499 140.723 124.063 1.00 141.93 ? 157 ASN R C   1 
ATOM 5329 O O   . ASN E 5 221 ? 141.521 141.506 123.116 1.00 143.82 ? 157 ASN R O   1 
ATOM 5330 C CB  . ASN E 5 221 ? 143.108 139.116 125.135 1.00 141.20 ? 157 ASN R CB  1 
ATOM 5331 C CG  . ASN E 5 221 ? 144.406 139.900 125.019 1.00 142.26 ? 157 ASN R CG  1 
ATOM 5332 O OD1 . ASN E 5 221 ? 144.453 140.969 124.412 1.00 143.42 ? 157 ASN R OD1 1 
ATOM 5333 N ND2 . ASN E 5 221 ? 145.471 139.365 125.607 1.00 140.82 ? 157 ASN R ND2 1 
ATOM 5334 N N   . ARG E 5 222 ? 140.904 140.989 125.233 1.00 148.34 ? 158 ARG R N   1 
ATOM 5335 C CA  . ARG E 5 222 ? 140.189 142.246 125.460 1.00 152.99 ? 158 ARG R CA  1 
ATOM 5336 C C   . ARG E 5 222 ? 141.071 143.471 125.289 1.00 153.52 ? 158 ARG R C   1 
ATOM 5337 O O   . ARG E 5 222 ? 140.696 144.369 124.517 1.00 152.30 ? 158 ARG R O   1 
ATOM 5338 C CB  . ARG E 5 222 ? 139.560 142.241 126.862 1.00 152.83 ? 158 ARG R CB  1 
ATOM 5339 N N   . PRO E 5 223 ? 142.226 143.585 125.958 1.00 137.26 ? 159 PRO R N   1 
ATOM 5340 C CA  . PRO E 5 223 ? 142.990 144.840 125.859 1.00 137.20 ? 159 PRO R CA  1 
ATOM 5341 C C   . PRO E 5 223 ? 143.560 145.105 124.478 1.00 137.87 ? 159 PRO R C   1 
ATOM 5342 O O   . PRO E 5 223 ? 143.697 146.274 124.089 1.00 140.78 ? 159 PRO R O   1 
ATOM 5343 C CB  . PRO E 5 223 ? 144.099 144.650 126.901 1.00 136.89 ? 159 PRO R CB  1 
ATOM 5344 C CG  . PRO E 5 223 ? 144.280 143.195 126.975 1.00 134.62 ? 159 PRO R CG  1 
ATOM 5345 C CD  . PRO E 5 223 ? 142.920 142.600 126.805 1.00 132.95 ? 159 PRO R CD  1 
ATOM 5346 N N   . VAL E 5 224 ? 143.893 144.063 123.719 1.00 125.47 ? 160 VAL R N   1 
ATOM 5347 C CA  . VAL E 5 224 ? 144.349 144.273 122.351 1.00 124.33 ? 160 VAL R CA  1 
ATOM 5348 C C   . VAL E 5 224 ? 143.222 144.839 121.500 1.00 128.57 ? 160 VAL R C   1 
ATOM 5349 O O   . VAL E 5 224 ? 143.431 145.752 120.691 1.00 130.44 ? 160 VAL R O   1 
ATOM 5350 C CB  . VAL E 5 224 ? 144.904 142.963 121.768 1.00 123.76 ? 160 VAL R CB  1 
ATOM 5351 C CG1 . VAL E 5 224 ? 144.717 142.930 120.263 1.00 125.06 ? 160 VAL R CG1 1 
ATOM 5352 C CG2 . VAL E 5 224 ? 146.371 142.808 122.134 1.00 125.95 ? 160 VAL R CG2 1 
ATOM 5353 N N   . LEU E 5 225 ? 142.010 144.307 121.666 1.00 144.43 ? 161 LEU R N   1 
ATOM 5354 C CA  . LEU E 5 225 ? 140.864 144.877 120.971 1.00 146.92 ? 161 LEU R CA  1 
ATOM 5355 C C   . LEU E 5 225 ? 140.583 146.300 121.433 1.00 147.21 ? 161 LEU R C   1 
ATOM 5356 O O   . LEU E 5 225 ? 140.127 147.125 120.640 1.00 146.64 ? 161 LEU R O   1 
ATOM 5357 C CB  . LEU E 5 225 ? 139.633 143.996 121.168 1.00 147.96 ? 161 LEU R CB  1 
ATOM 5358 C CG  . LEU E 5 225 ? 139.676 142.675 120.405 1.00 146.62 ? 161 LEU R CG  1 
ATOM 5359 C CD1 . LEU E 5 225 ? 138.374 141.909 120.580 1.00 145.98 ? 161 LEU R CD1 1 
ATOM 5360 C CD2 . LEU E 5 225 ? 139.963 142.932 118.936 1.00 144.02 ? 161 LEU R CD2 1 
ATOM 5361 N N   . VAL E 5 226 ? 140.846 146.609 122.703 1.00 148.79 ? 162 VAL R N   1 
ATOM 5362 C CA  . VAL E 5 226 ? 140.676 147.981 123.180 1.00 150.04 ? 162 VAL R CA  1 
ATOM 5363 C C   . VAL E 5 226 ? 141.645 148.914 122.461 1.00 151.21 ? 162 VAL R C   1 
ATOM 5364 O O   . VAL E 5 226 ? 141.266 149.996 121.991 1.00 148.07 ? 162 VAL R O   1 
ATOM 5365 C CB  . VAL E 5 226 ? 140.852 148.040 124.709 1.00 149.48 ? 162 VAL R CB  1 
ATOM 5366 C CG1 . VAL E 5 226 ? 141.028 149.474 125.176 1.00 149.92 ? 162 VAL R CG1 1 
ATOM 5367 C CG2 . VAL E 5 226 ? 139.656 147.396 125.397 1.00 148.93 ? 162 VAL R CG2 1 
ATOM 5368 N N   . ALA E 5 227 ? 142.910 148.497 122.350 1.00 147.39 ? 163 ALA R N   1 
ATOM 5369 C CA  . ALA E 5 227 ? 143.894 149.304 121.633 1.00 144.78 ? 163 ALA R CA  1 
ATOM 5370 C C   . ALA E 5 227 ? 143.510 149.467 120.166 1.00 142.60 ? 163 ALA R C   1 
ATOM 5371 O O   . ALA E 5 227 ? 143.637 150.561 119.600 1.00 144.65 ? 163 ALA R O   1 
ATOM 5372 C CB  . ALA E 5 227 ? 145.284 148.681 121.761 1.00 141.00 ? 163 ALA R CB  1 
ATOM 5373 N N   . TRP E 5 228 ? 143.029 148.392 119.537 1.00 124.75 ? 164 TRP R N   1 
ATOM 5374 C CA  . TRP E 5 228 ? 142.598 148.482 118.145 1.00 125.97 ? 164 TRP R CA  1 
ATOM 5375 C C   . TRP E 5 228 ? 141.410 149.421 117.989 1.00 129.49 ? 164 TRP R C   1 
ATOM 5376 O O   . TRP E 5 228 ? 141.353 150.207 117.038 1.00 128.07 ? 164 TRP R O   1 
ATOM 5377 C CB  . TRP E 5 228 ? 142.244 147.099 117.601 1.00 127.61 ? 164 TRP R CB  1 
ATOM 5378 C CG  . TRP E 5 228 ? 143.412 146.316 117.091 1.00 128.66 ? 164 TRP R CG  1 
ATOM 5379 C CD1 . TRP E 5 228 ? 143.829 145.095 117.528 1.00 129.83 ? 164 TRP R CD1 1 
ATOM 5380 C CD2 . TRP E 5 228 ? 144.313 146.698 116.044 1.00 129.27 ? 164 TRP R CD2 1 
ATOM 5381 N NE1 . TRP E 5 228 ? 144.934 144.691 116.819 1.00 128.79 ? 164 TRP R NE1 1 
ATOM 5382 C CE2 . TRP E 5 228 ? 145.251 145.657 115.902 1.00 128.98 ? 164 TRP R CE2 1 
ATOM 5383 C CE3 . TRP E 5 228 ? 144.418 147.818 115.215 1.00 129.70 ? 164 TRP R CE3 1 
ATOM 5384 C CZ2 . TRP E 5 228 ? 146.280 145.703 114.967 1.00 127.17 ? 164 TRP R CZ2 1 
ATOM 5385 C CZ3 . TRP E 5 228 ? 145.441 147.861 114.287 1.00 127.20 ? 164 TRP R CZ3 1 
ATOM 5386 C CH2 . TRP E 5 228 ? 146.358 146.811 114.171 1.00 123.92 ? 164 TRP R CH2 1 
ATOM 5387 N N   . ALA E 5 229 ? 140.440 149.338 118.901 1.00 147.99 ? 165 ALA R N   1 
ATOM 5388 C CA  . ALA E 5 229 ? 139.273 150.208 118.828 1.00 149.55 ? 165 ALA R CA  1 
ATOM 5389 C C   . ALA E 5 229 ? 139.673 151.665 118.982 1.00 149.13 ? 165 ALA R C   1 
ATOM 5390 O O   . ALA E 5 229 ? 139.134 152.538 118.294 1.00 147.38 ? 165 ALA R O   1 
ATOM 5391 C CB  . ALA E 5 229 ? 138.252 149.811 119.893 1.00 149.75 ? 165 ALA R CB  1 
ATOM 5392 N N   . PHE E 5 230 ? 140.619 151.951 119.878 1.00 154.19 ? 166 PHE R N   1 
ATOM 5393 C CA  . PHE E 5 230 ? 141.109 153.321 120.002 1.00 154.42 ? 166 PHE R CA  1 
ATOM 5394 C C   . PHE E 5 230 ? 141.790 153.778 118.719 1.00 155.62 ? 166 PHE R C   1 
ATOM 5395 O O   . PHE E 5 230 ? 141.519 154.875 118.217 1.00 153.67 ? 166 PHE R O   1 
ATOM 5396 C CB  . PHE E 5 230 ? 142.063 153.447 121.187 1.00 152.09 ? 166 PHE R CB  1 
ATOM 5397 C CG  . PHE E 5 230 ? 141.371 153.674 122.494 1.00 156.16 ? 166 PHE R CG  1 
ATOM 5398 C CD1 . PHE E 5 230 ? 140.523 154.753 122.659 1.00 158.52 ? 166 PHE R CD1 1 
ATOM 5399 C CD2 . PHE E 5 230 ? 141.571 152.817 123.560 1.00 156.70 ? 166 PHE R CD2 1 
ATOM 5400 C CE1 . PHE E 5 230 ? 139.880 154.971 123.858 1.00 159.04 ? 166 PHE R CE1 1 
ATOM 5401 C CE2 . PHE E 5 230 ? 140.930 153.030 124.766 1.00 155.91 ? 166 PHE R CE2 1 
ATOM 5402 C CZ  . PHE E 5 230 ? 140.084 154.109 124.914 1.00 156.09 ? 166 PHE R CZ  1 
ATOM 5403 N N   . SER E 5 231 ? 142.664 152.935 118.158 1.00 157.71 ? 167 SER R N   1 
ATOM 5404 C CA  . SER E 5 231 ? 143.394 153.337 116.961 1.00 157.00 ? 167 SER R CA  1 
ATOM 5405 C C   . SER E 5 231 ? 142.466 153.512 115.770 1.00 159.14 ? 167 SER R C   1 
ATOM 5406 O O   . SER E 5 231 ? 142.747 154.322 114.882 1.00 161.58 ? 167 SER R O   1 
ATOM 5407 C CB  . SER E 5 231 ? 144.492 152.323 116.643 1.00 153.88 ? 167 SER R CB  1 
ATOM 5408 O OG  . SER E 5 231 ? 143.951 151.050 116.349 1.00 152.40 ? 167 SER R OG  1 
ATOM 5409 N N   . LEU E 5 232 ? 141.353 152.782 115.743 1.00 159.06 ? 168 LEU R N   1 
ATOM 5410 C CA  . LEU E 5 232 ? 140.413 152.903 114.636 1.00 158.86 ? 168 LEU R CA  1 
ATOM 5411 C C   . LEU E 5 232 ? 139.498 154.108 114.813 1.00 159.50 ? 168 LEU R C   1 
ATOM 5412 O O   . LEU E 5 232 ? 139.354 154.925 113.897 1.00 159.64 ? 168 LEU R O   1 
ATOM 5413 C CB  . LEU E 5 232 ? 139.591 151.620 114.503 1.00 156.48 ? 168 LEU R CB  1 
ATOM 5414 N N   . LEU E 5 233 ? 138.874 154.235 115.989 1.00 161.86 ? 169 LEU R N   1 
ATOM 5415 C CA  . LEU E 5 233 ? 137.938 155.327 116.228 1.00 163.28 ? 169 LEU R CA  1 
ATOM 5416 C C   . LEU E 5 233 ? 138.634 156.682 116.186 1.00 162.19 ? 169 LEU R C   1 
ATOM 5417 O O   . LEU E 5 233 ? 138.099 157.642 115.621 1.00 162.61 ? 169 LEU R O   1 
ATOM 5418 C CB  . LEU E 5 233 ? 137.234 155.126 117.571 1.00 164.54 ? 169 LEU R CB  1 
ATOM 5419 N N   . LEU E 5 234 ? 139.831 156.782 116.770 1.00 155.97 ? 170 LEU R N   1 
ATOM 5420 C CA  . LEU E 5 234 ? 140.509 158.071 116.819 1.00 155.82 ? 170 LEU R CA  1 
ATOM 5421 C C   . LEU E 5 234 ? 141.052 158.507 115.466 1.00 154.32 ? 170 LEU R C   1 
ATOM 5422 O O   . LEU E 5 234 ? 141.483 159.658 115.333 1.00 153.35 ? 170 LEU R O   1 
ATOM 5423 C CB  . LEU E 5 234 ? 141.640 158.035 117.846 1.00 154.55 ? 170 LEU R CB  1 
ATOM 5424 C CG  . LEU E 5 234 ? 141.197 157.951 119.307 1.00 154.90 ? 170 LEU R CG  1 
ATOM 5425 C CD1 . LEU E 5 234 ? 142.389 158.061 120.244 1.00 154.52 ? 170 LEU R CD1 1 
ATOM 5426 C CD2 . LEU E 5 234 ? 140.164 159.023 119.619 1.00 157.01 ? 170 LEU R CD2 1 
ATOM 5427 N N   . SER E 5 235 ? 141.047 157.630 114.469 1.00 159.42 ? 171 SER R N   1 
ATOM 5428 C CA  . SER E 5 235 ? 141.426 158.000 113.115 1.00 161.59 ? 171 SER R CA  1 
ATOM 5429 C C   . SER E 5 235 ? 140.230 158.322 112.234 1.00 164.22 ? 171 SER R C   1 
ATOM 5430 O O   . SER E 5 235 ? 140.422 158.726 111.083 1.00 165.83 ? 171 SER R O   1 
ATOM 5431 C CB  . SER E 5 235 ? 142.244 156.883 112.470 1.00 163.24 ? 171 SER R CB  1 
ATOM 5432 O OG  . SER E 5 235 ? 143.340 156.534 113.290 1.00 166.24 ? 171 SER R OG  1 
ATOM 5433 N N   . LEU E 5 236 ? 139.012 158.145 112.739 1.00 161.54 ? 172 LEU R N   1 
ATOM 5434 C CA  . LEU E 5 236 ? 137.824 158.429 111.939 1.00 161.36 ? 172 LEU R CA  1 
ATOM 5435 C C   . LEU E 5 236 ? 137.794 159.844 111.369 1.00 160.30 ? 172 LEU R C   1 
ATOM 5436 O O   . LEU E 5 236 ? 137.331 160.002 110.227 1.00 159.45 ? 172 LEU R O   1 
ATOM 5437 C CB  . LEU E 5 236 ? 136.561 158.145 112.766 1.00 160.56 ? 172 LEU R CB  1 
ATOM 5438 N N   . PRO E 5 237 ? 138.248 160.892 112.071 1.00 161.75 ? 173 PRO R N   1 
ATOM 5439 C CA  . PRO E 5 237 ? 138.257 162.225 111.447 1.00 162.92 ? 173 PRO R CA  1 
ATOM 5440 C C   . PRO E 5 237 ? 139.030 162.296 110.145 1.00 163.95 ? 173 PRO R C   1 
ATOM 5441 O O   . PRO E 5 237 ? 138.731 163.159 109.318 1.00 163.68 ? 173 PRO R O   1 
ATOM 5442 C CB  . PRO E 5 237 ? 138.901 163.104 112.525 1.00 162.95 ? 173 PRO R CB  1 
ATOM 5443 C CG  . PRO E 5 237 ? 138.502 162.459 113.788 1.00 161.09 ? 173 PRO R CG  1 
ATOM 5444 C CD  . PRO E 5 237 ? 138.547 160.981 113.513 1.00 161.45 ? 173 PRO R CD  1 
ATOM 5445 N N   . GLN E 5 238 ? 140.005 161.412 109.929 1.00 166.73 ? 174 GLN R N   1 
ATOM 5446 C CA  . GLN E 5 238 ? 140.732 161.408 108.666 1.00 167.82 ? 174 GLN R CA  1 
ATOM 5447 C C   . GLN E 5 238 ? 139.821 161.144 107.477 1.00 169.93 ? 174 GLN R C   1 
ATOM 5448 O O   . GLN E 5 238 ? 140.190 161.472 106.346 1.00 169.71 ? 174 GLN R O   1 
ATOM 5449 C CB  . GLN E 5 238 ? 141.844 160.365 108.703 1.00 166.01 ? 174 GLN R CB  1 
ATOM 5450 C CG  . GLN E 5 238 ? 142.825 160.556 109.837 1.00 164.58 ? 174 GLN R CG  1 
ATOM 5451 C CD  . GLN E 5 238 ? 143.632 161.827 109.695 1.00 166.68 ? 174 GLN R CD  1 
ATOM 5452 O OE1 . GLN E 5 238 ? 144.200 162.098 108.638 1.00 166.57 ? 174 GLN R OE1 1 
ATOM 5453 N NE2 . GLN E 5 238 ? 143.685 162.618 110.761 1.00 170.52 ? 174 GLN R NE2 1 
ATOM 5454 N N   . LEU E 5 239 ? 138.648 160.561 107.701 1.00 184.30 ? 175 LEU R N   1 
ATOM 5455 C CA  . LEU E 5 239 ? 137.705 160.336 106.615 1.00 183.94 ? 175 LEU R CA  1 
ATOM 5456 C C   . LEU E 5 239 ? 136.902 161.579 106.261 1.00 183.49 ? 175 LEU R C   1 
ATOM 5457 O O   . LEU E 5 239 ? 136.093 161.522 105.331 1.00 183.19 ? 175 LEU R O   1 
ATOM 5458 C CB  . LEU E 5 239 ? 136.752 159.192 106.963 1.00 183.94 ? 175 LEU R CB  1 
ATOM 5459 N N   . PHE E 5 240 ? 137.081 162.689 106.984 1.00 182.23 ? 176 PHE R N   1 
ATOM 5460 C CA  . PHE E 5 240 ? 136.544 163.968 106.543 1.00 181.50 ? 176 PHE R CA  1 
ATOM 5461 C C   . PHE E 5 240 ? 137.574 165.088 106.517 1.00 180.40 ? 176 PHE R C   1 
ATOM 5462 O O   . PHE E 5 240 ? 137.289 166.138 105.935 1.00 180.87 ? 176 PHE R O   1 
ATOM 5463 C CB  . PHE E 5 240 ? 135.352 164.398 107.415 1.00 181.52 ? 176 PHE R CB  1 
ATOM 5464 N N   . ILE E 5 241 ? 138.753 164.905 107.116 1.00 175.11 ? 177 ILE R N   1 
ATOM 5465 C CA  . ILE E 5 241 ? 139.796 165.925 107.054 1.00 176.37 ? 177 ILE R CA  1 
ATOM 5466 C C   . ILE E 5 241 ? 140.393 166.000 105.652 1.00 177.99 ? 177 ILE R C   1 
ATOM 5467 O O   . ILE E 5 241 ? 140.515 167.084 105.070 1.00 179.06 ? 177 ILE R O   1 
ATOM 5468 C CB  . ILE E 5 241 ? 140.883 165.649 108.109 1.00 176.79 ? 177 ILE R CB  1 
ATOM 5469 C CG1 . ILE E 5 241 ? 140.326 165.854 109.519 1.00 176.50 ? 177 ILE R CG1 1 
ATOM 5470 C CG2 . ILE E 5 241 ? 142.105 166.528 107.859 1.00 178.17 ? 177 ILE R CG2 1 
ATOM 5471 C CD1 . ILE E 5 241 ? 141.264 165.400 110.612 1.00 177.53 ? 177 ILE R CD1 1 
ATOM 5472 N N   . PHE E 5 242 ? 140.770 164.854 105.087 1.00 183.20 ? 178 PHE R N   1 
ATOM 5473 C CA  . PHE E 5 242 ? 141.457 164.798 103.800 1.00 184.18 ? 178 PHE R CA  1 
ATOM 5474 C C   . PHE E 5 242 ? 140.470 164.510 102.679 1.00 183.60 ? 178 PHE R C   1 
ATOM 5475 O O   . PHE E 5 242 ? 139.637 163.603 102.791 1.00 183.61 ? 178 PHE R O   1 
ATOM 5476 C CB  . PHE E 5 242 ? 142.548 163.729 103.795 1.00 183.97 ? 178 PHE R CB  1 
ATOM 5477 C CG  . PHE E 5 242 ? 143.817 164.150 104.464 1.00 183.27 ? 178 PHE R CG  1 
ATOM 5478 C CD1 . PHE E 5 242 ? 143.971 164.007 105.828 1.00 181.82 ? 178 PHE R CD1 1 
ATOM 5479 C CD2 . PHE E 5 242 ? 144.863 164.669 103.727 1.00 182.43 ? 178 PHE R CD2 1 
ATOM 5480 C CE1 . PHE E 5 242 ? 145.138 164.384 106.449 1.00 179.99 ? 178 PHE R CE1 1 
ATOM 5481 C CE2 . PHE E 5 242 ? 146.037 165.050 104.345 1.00 179.90 ? 178 PHE R CE2 1 
ATOM 5482 C CZ  . PHE E 5 242 ? 146.174 164.906 105.709 1.00 179.04 ? 178 PHE R CZ  1 
ATOM 5483 N N   . ALA E 5 243 ? 140.576 165.276 101.600 1.00 196.71 ? 179 ALA R N   1 
ATOM 5484 C CA  . ALA E 5 243 ? 139.779 165.073 100.397 1.00 196.58 ? 179 ALA R CA  1 
ATOM 5485 C C   . ALA E 5 243 ? 140.386 165.916 99.282  1.00 196.32 ? 179 ALA R C   1 
ATOM 5486 O O   . ALA E 5 243 ? 141.096 166.888 99.552  1.00 196.83 ? 179 ALA R O   1 
ATOM 5487 C CB  . ALA E 5 243 ? 138.309 165.441 100.617 1.00 196.15 ? 179 ALA R CB  1 
ATOM 5488 N N   . GLN E 5 244 ? 140.121 165.524 98.036  1.00 90.65  ? 180 GLN R N   1 
ATOM 5489 C CA  . GLN E 5 244 ? 140.678 166.248 96.886  1.00 89.86  ? 180 GLN R CA  1 
ATOM 5490 C C   . GLN E 5 244 ? 140.638 167.762 97.122  1.00 89.73  ? 180 GLN R C   1 
ATOM 5491 O O   . GLN E 5 244 ? 141.275 168.505 96.376  1.00 87.55  ? 180 GLN R O   1 
ATOM 5492 C CB  . GLN E 5 244 ? 139.930 165.892 95.595  1.00 88.23  ? 180 GLN R CB  1 
ATOM 5493 N N   . THR E 5 254 ? 145.941 166.208 91.078  1.00 87.40  ? 190 THR R N   1 
ATOM 5494 C CA  . THR E 5 254 ? 145.182 166.495 92.288  1.00 88.15  ? 190 THR R CA  1 
ATOM 5495 C C   . THR E 5 254 ? 145.568 165.541 93.413  1.00 88.48  ? 190 THR R C   1 
ATOM 5496 O O   . THR E 5 254 ? 146.031 164.428 93.162  1.00 85.70  ? 190 THR R O   1 
ATOM 5497 C CB  . THR E 5 254 ? 143.664 166.396 92.038  1.00 86.77  ? 190 THR R CB  1 
ATOM 5498 O OG1 . THR E 5 254 ? 143.340 165.084 91.564  1.00 77.66  ? 190 THR R OG1 1 
ATOM 5499 C CG2 . THR E 5 254 ? 143.225 167.422 91.007  1.00 77.84  ? 190 THR R CG2 1 
ATOM 5500 N N   . ASP E 5 255 ? 145.373 165.984 94.652  1.00 208.89 ? 191 ASP R N   1 
ATOM 5501 C CA  . ASP E 5 255 ? 145.650 165.163 95.824  1.00 209.80 ? 191 ASP R CA  1 
ATOM 5502 C C   . ASP E 5 255 ? 144.843 165.719 96.992  1.00 210.57 ? 191 ASP R C   1 
ATOM 5503 O O   . ASP E 5 255 ? 144.142 166.727 96.863  1.00 210.95 ? 191 ASP R O   1 
ATOM 5504 C CB  . ASP E 5 255 ? 147.150 165.119 96.129  1.00 210.37 ? 191 ASP R CB  1 
ATOM 5505 C CG  . ASP E 5 255 ? 147.604 163.755 96.616  1.00 210.50 ? 191 ASP R CG  1 
ATOM 5506 O OD1 . ASP E 5 255 ? 146.864 163.119 97.393  1.00 210.15 ? 191 ASP R OD1 1 
ATOM 5507 O OD2 . ASP E 5 255 ? 148.698 163.310 96.215  1.00 210.61 ? 191 ASP R OD2 1 
ATOM 5508 N N   . CYS E 5 256 ? 144.944 165.053 98.139  1.00 213.70 ? 192 CYS R N   1 
ATOM 5509 C CA  . CYS E 5 256 ? 144.097 165.369 99.280  1.00 213.75 ? 192 CYS R CA  1 
ATOM 5510 C C   . CYS E 5 256 ? 144.735 166.428 100.168 1.00 213.08 ? 192 CYS R C   1 
ATOM 5511 O O   . CYS E 5 256 ? 145.936 166.389 100.449 1.00 213.14 ? 192 CYS R O   1 
ATOM 5512 C CB  . CYS E 5 256 ? 143.790 164.108 100.091 1.00 214.25 ? 192 CYS R CB  1 
ATOM 5513 S SG  . CYS E 5 256 ? 142.491 163.123 99.315  1.00 219.59 ? 192 CYS R SG  1 
ATOM 5514 N N   . TRP E 5 257 ? 143.911 167.373 100.606 1.00 205.23 ? 193 TRP R N   1 
ATOM 5515 C CA  . TRP E 5 257 ? 144.333 168.468 101.460 1.00 204.72 ? 193 TRP R CA  1 
ATOM 5516 C C   . TRP E 5 257 ? 143.608 168.371 102.792 1.00 205.39 ? 193 TRP R C   1 
ATOM 5517 O O   . TRP E 5 257 ? 142.486 167.856 102.871 1.00 204.88 ? 193 TRP R O   1 
ATOM 5518 C CB  . TRP E 5 257 ? 144.041 169.824 100.819 1.00 204.34 ? 193 TRP R CB  1 
ATOM 5519 C CG  . TRP E 5 257 ? 144.393 169.890 99.378  1.00 205.15 ? 193 TRP R CG  1 
ATOM 5520 C CD1 . TRP E 5 257 ? 143.632 169.466 98.333  1.00 205.84 ? 193 TRP R CD1 1 
ATOM 5521 C CD2 . TRP E 5 257 ? 145.597 170.422 98.811  1.00 204.86 ? 193 TRP R CD2 1 
ATOM 5522 N NE1 . TRP E 5 257 ? 144.286 169.693 97.149  1.00 205.83 ? 193 TRP R NE1 1 
ATOM 5523 C CE2 . TRP E 5 257 ? 145.495 170.281 97.414  1.00 205.57 ? 193 TRP R CE2 1 
ATOM 5524 C CE3 . TRP E 5 257 ? 146.749 171.002 99.350  1.00 204.04 ? 193 TRP R CE3 1 
ATOM 5525 C CZ2 . TRP E 5 257 ? 146.501 170.697 96.550  1.00 205.25 ? 193 TRP R CZ2 1 
ATOM 5526 C CZ3 . TRP E 5 257 ? 147.747 171.415 98.488  1.00 204.26 ? 193 TRP R CZ3 1 
ATOM 5527 C CH2 . TRP E 5 257 ? 147.610 171.251 97.119  1.00 204.36 ? 193 TRP R CH2 1 
ATOM 5528 N N   . ALA E 5 258 ? 144.259 168.850 103.847 1.00 208.50 ? 194 ALA R N   1 
ATOM 5529 C CA  . ALA E 5 258 ? 143.680 168.866 105.166 1.00 208.60 ? 194 ALA R CA  1 
ATOM 5530 C C   . ALA E 5 258 ? 143.108 170.227 105.491 1.00 208.14 ? 194 ALA R C   1 
ATOM 5531 O O   . ALA E 5 258 ? 143.086 170.643 106.659 1.00 206.11 ? 194 ALA R O   1 
ATOM 5532 C CB  . ALA E 5 258 ? 144.716 168.440 106.211 1.00 206.41 ? 194 ALA R CB  1 
ATOM 5533 N N   . CYS E 5 259 ? 142.669 170.962 104.449 1.00 211.60 ? 195 CYS R N   1 
ATOM 5534 C CA  . CYS E 5 259 ? 142.106 172.291 104.631 1.00 210.64 ? 195 CYS R CA  1 
ATOM 5535 C C   . CYS E 5 259 ? 141.146 172.278 105.801 1.00 209.08 ? 195 CYS R C   1 
ATOM 5536 O O   . CYS E 5 259 ? 140.216 171.467 105.834 1.00 207.97 ? 195 CYS R O   1 
ATOM 5537 C CB  . CYS E 5 259 ? 141.353 172.747 103.369 1.00 210.66 ? 195 CYS R CB  1 
ATOM 5538 N N   . PHE E 5 260 ? 141.375 173.165 106.799 1.00 188.85 ? 196 PHE R N   1 
ATOM 5539 C CA  . PHE E 5 260 ? 140.546 173.213 108.006 1.00 188.91 ? 196 PHE R CA  1 
ATOM 5540 C C   . PHE E 5 260 ? 140.468 171.814 108.627 1.00 189.16 ? 196 PHE R C   1 
ATOM 5541 O O   . PHE E 5 260 ? 139.366 171.323 108.879 1.00 188.52 ? 196 PHE R O   1 
ATOM 5542 C CB  . PHE E 5 260 ? 139.149 173.760 107.663 1.00 190.06 ? 196 PHE R CB  1 
ATOM 5543 N N   . TRP E 5 264 ? 141.063 178.018 112.441 1.00 180.82 ? 200 TRP R N   1 
ATOM 5544 C CA  . TRP E 5 264 ? 142.316 177.374 112.100 1.00 180.85 ? 200 TRP R CA  1 
ATOM 5545 C C   . TRP E 5 264 ? 142.169 175.895 112.365 1.00 183.10 ? 200 TRP R C   1 
ATOM 5546 O O   . TRP E 5 264 ? 141.345 175.477 113.181 1.00 181.75 ? 200 TRP R O   1 
ATOM 5547 C CB  . TRP E 5 264 ? 143.490 177.957 112.904 1.00 180.57 ? 200 TRP R CB  1 
ATOM 5548 C CG  . TRP E 5 264 ? 143.374 177.792 114.406 1.00 180.31 ? 200 TRP R CG  1 
ATOM 5549 C CD1 . TRP E 5 264 ? 143.462 176.631 115.112 1.00 179.60 ? 200 TRP R CD1 1 
ATOM 5550 C CD2 . TRP E 5 264 ? 143.179 178.831 115.373 1.00 180.65 ? 200 TRP R CD2 1 
ATOM 5551 N NE1 . TRP E 5 264 ? 143.316 176.877 116.452 1.00 180.71 ? 200 TRP R NE1 1 
ATOM 5552 C CE2 . TRP E 5 264 ? 143.148 178.221 116.640 1.00 181.00 ? 200 TRP R CE2 1 
ATOM 5553 C CE3 . TRP E 5 264 ? 143.024 180.213 115.290 1.00 179.83 ? 200 TRP R CE3 1 
ATOM 5554 C CZ2 . TRP E 5 264 ? 142.966 178.943 117.810 1.00 180.07 ? 200 TRP R CZ2 1 
ATOM 5555 C CZ3 . TRP E 5 264 ? 142.843 180.927 116.451 1.00 181.06 ? 200 TRP R CZ3 1 
ATOM 5556 C CH2 . TRP E 5 264 ? 142.815 180.292 117.696 1.00 181.44 ? 200 TRP R CH2 1 
ATOM 5557 N N   . GLY E 5 265 ? 142.969 175.098 111.675 1.00 176.11 ? 201 GLY R N   1 
ATOM 5558 C CA  . GLY E 5 265 ? 142.932 173.673 111.897 1.00 174.26 ? 201 GLY R CA  1 
ATOM 5559 C C   . GLY E 5 265 ? 144.275 173.105 112.288 1.00 172.55 ? 201 GLY R C   1 
ATOM 5560 O O   . GLY E 5 265 ? 144.346 172.002 112.842 1.00 171.07 ? 201 GLY R O   1 
ATOM 5561 N N   . ARG E 5 266 ? 145.344 173.861 112.029 1.00 157.33 ? 202 ARG R N   1 
ATOM 5562 C CA  . ARG E 5 266 ? 146.692 173.321 112.167 1.00 156.45 ? 202 ARG R CA  1 
ATOM 5563 C C   . ARG E 5 266 ? 146.960 172.891 113.599 1.00 158.54 ? 202 ARG R C   1 
ATOM 5564 O O   . ARG E 5 266 ? 147.151 171.704 113.877 1.00 163.04 ? 202 ARG R O   1 
ATOM 5565 C CB  . ARG E 5 266 ? 147.723 174.352 111.707 1.00 153.37 ? 202 ARG R CB  1 
ATOM 5566 C CG  . ARG E 5 266 ? 147.687 174.683 110.222 1.00 150.99 ? 202 ARG R CG  1 
ATOM 5567 C CD  . ARG E 5 266 ? 148.211 173.538 109.374 1.00 154.57 ? 202 ARG R CD  1 
ATOM 5568 N NE  . ARG E 5 266 ? 147.163 172.574 109.078 1.00 159.27 ? 202 ARG R NE  1 
ATOM 5569 C CZ  . ARG E 5 266 ? 146.320 172.686 108.063 1.00 158.80 ? 202 ARG R CZ  1 
ATOM 5570 N NH1 . ARG E 5 266 ? 146.413 173.680 107.195 1.00 157.67 ? 202 ARG R NH1 1 
ATOM 5571 N NH2 . ARG E 5 266 ? 145.362 171.777 107.913 1.00 158.52 ? 202 ARG R NH2 1 
ATOM 5572 N N   . ARG E 5 267 ? 146.945 173.843 114.534 1.00 140.06 ? 203 ARG R N   1 
ATOM 5573 C CA  . ARG E 5 267 ? 147.159 173.480 115.929 1.00 136.12 ? 203 ARG R CA  1 
ATOM 5574 C C   . ARG E 5 267 ? 146.043 172.593 116.459 1.00 138.81 ? 203 ARG R C   1 
ATOM 5575 O O   . ARG E 5 267 ? 146.298 171.762 117.329 1.00 138.73 ? 203 ARG R O   1 
ATOM 5576 C CB  . ARG E 5 267 ? 147.323 174.727 116.795 1.00 136.37 ? 203 ARG R CB  1 
ATOM 5577 N N   . THR E 5 268 ? 144.834 172.682 115.901 1.00 151.99 ? 204 THR R N   1 
ATOM 5578 C CA  . THR E 5 268 ? 143.724 171.865 116.377 1.00 153.28 ? 204 THR R CA  1 
ATOM 5579 C C   . THR E 5 268 ? 144.017 170.376 116.220 1.00 151.76 ? 204 THR R C   1 
ATOM 5580 O O   . THR E 5 268 ? 144.228 169.652 117.205 1.00 154.60 ? 204 THR R O   1 
ATOM 5581 C CB  . THR E 5 268 ? 142.453 172.228 115.609 1.00 153.16 ? 204 THR R CB  1 
ATOM 5582 O OG1 . THR E 5 268 ? 142.126 173.602 115.848 1.00 156.70 ? 204 THR R OG1 1 
ATOM 5583 C CG2 . THR E 5 268 ? 141.299 171.351 116.034 1.00 148.30 ? 204 THR R CG2 1 
ATOM 5584 N N   . TYR E 5 269 ? 144.080 169.927 114.967 1.00 139.71 ? 205 TYR R N   1 
ATOM 5585 C CA  . TYR E 5 269 ? 144.319 168.513 114.718 1.00 138.83 ? 205 TYR R CA  1 
ATOM 5586 C C   . TYR E 5 269 ? 145.740 168.122 115.071 1.00 135.81 ? 205 TYR R C   1 
ATOM 5587 O O   . TYR E 5 269 ? 145.978 166.979 115.474 1.00 140.14 ? 205 TYR R O   1 
ATOM 5588 C CB  . TYR E 5 269 ? 144.017 168.179 113.262 1.00 140.00 ? 205 TYR R CB  1 
ATOM 5589 C CG  . TYR E 5 269 ? 142.587 168.458 112.868 1.00 140.21 ? 205 TYR R CG  1 
ATOM 5590 C CD1 . TYR E 5 269 ? 141.553 167.657 113.332 1.00 141.73 ? 205 TYR R CD1 1 
ATOM 5591 C CD2 . TYR E 5 269 ? 142.269 169.520 112.033 1.00 142.65 ? 205 TYR R CD2 1 
ATOM 5592 C CE1 . TYR E 5 269 ? 140.243 167.905 112.976 1.00 143.39 ? 205 TYR R CE1 1 
ATOM 5593 C CE2 . TYR E 5 269 ? 140.960 169.776 111.670 1.00 145.01 ? 205 TYR R CE2 1 
ATOM 5594 C CZ  . TYR E 5 269 ? 139.951 168.964 112.145 1.00 144.65 ? 205 TYR R CZ  1 
ATOM 5595 O OH  . TYR E 5 269 ? 138.644 169.208 111.791 1.00 143.93 ? 205 TYR R OH  1 
ATOM 5596 N N   . VAL E 5 270 ? 146.698 169.042 114.946 1.00 109.79 ? 206 VAL R N   1 
ATOM 5597 C CA  . VAL E 5 270 ? 148.064 168.703 115.306 1.00 109.35 ? 206 VAL R CA  1 
ATOM 5598 C C   . VAL E 5 270 ? 148.169 168.414 116.795 1.00 115.02 ? 206 VAL R C   1 
ATOM 5599 O O   . VAL E 5 270 ? 148.807 167.439 117.200 1.00 128.15 ? 206 VAL R O   1 
ATOM 5600 C CB  . VAL E 5 270 ? 149.030 169.818 114.868 1.00 115.68 ? 206 VAL R CB  1 
ATOM 5601 C CG1 . VAL E 5 270 ? 150.294 169.753 115.689 1.00 112.14 ? 206 VAL R CG1 1 
ATOM 5602 C CG2 . VAL E 5 270 ? 149.375 169.659 113.401 1.00 123.41 ? 206 VAL R CG2 1 
ATOM 5603 N N   . THR E 5 271 ? 147.549 169.246 117.638 1.00 122.52 ? 207 THR R N   1 
ATOM 5604 C CA  . THR E 5 271 ? 147.571 168.982 119.070 1.00 125.35 ? 207 THR R CA  1 
ATOM 5605 C C   . THR E 5 271 ? 146.813 167.704 119.401 1.00 121.64 ? 207 THR R C   1 
ATOM 5606 O O   . THR E 5 271 ? 147.282 166.897 120.213 1.00 119.14 ? 207 THR R O   1 
ATOM 5607 C CB  . THR E 5 271 ? 146.995 170.175 119.836 1.00 129.55 ? 207 THR R CB  1 
ATOM 5608 O OG1 . THR E 5 271 ? 147.860 171.307 119.677 1.00 137.05 ? 207 THR R OG1 1 
ATOM 5609 C CG2 . THR E 5 271 ? 146.876 169.850 121.314 1.00 128.36 ? 207 THR R CG2 1 
ATOM 5610 N N   . TRP E 5 272 ? 145.655 167.485 118.768 1.00 109.91 ? 208 TRP R N   1 
ATOM 5611 C CA  . TRP E 5 272 ? 144.925 166.245 119.018 1.00 108.85 ? 208 TRP R CA  1 
ATOM 5612 C C   . TRP E 5 272 ? 145.782 165.029 118.699 1.00 110.71 ? 208 TRP R C   1 
ATOM 5613 O O   . TRP E 5 272 ? 145.877 164.095 119.502 1.00 107.86 ? 208 TRP R O   1 
ATOM 5614 C CB  . TRP E 5 272 ? 143.638 166.209 118.206 1.00 109.80 ? 208 TRP R CB  1 
ATOM 5615 C CG  . TRP E 5 272 ? 142.608 167.134 118.720 1.00 115.99 ? 208 TRP R CG  1 
ATOM 5616 C CD1 . TRP E 5 272 ? 142.615 167.783 119.918 1.00 113.10 ? 208 TRP R CD1 1 
ATOM 5617 C CD2 . TRP E 5 272 ? 141.408 167.534 118.052 1.00 119.53 ? 208 TRP R CD2 1 
ATOM 5618 N NE1 . TRP E 5 272 ? 141.491 168.562 120.039 1.00 115.67 ? 208 TRP R NE1 1 
ATOM 5619 C CE2 . TRP E 5 272 ? 140.733 168.427 118.906 1.00 122.20 ? 208 TRP R CE2 1 
ATOM 5620 C CE3 . TRP E 5 272 ? 140.839 167.222 116.814 1.00 114.56 ? 208 TRP R CE3 1 
ATOM 5621 C CZ2 . TRP E 5 272 ? 139.516 169.013 118.562 1.00 119.84 ? 208 TRP R CZ2 1 
ATOM 5622 C CZ3 . TRP E 5 272 ? 139.632 167.804 116.474 1.00 113.87 ? 208 TRP R CZ3 1 
ATOM 5623 C CH2 . TRP E 5 272 ? 138.983 168.689 117.344 1.00 117.50 ? 208 TRP R CH2 1 
ATOM 5624 N N   . ILE E 5 273 ? 146.429 165.032 117.533 1.00 121.79 ? 209 ILE R N   1 
ATOM 5625 C CA  . ILE E 5 273 ? 147.225 163.885 117.114 1.00 119.40 ? 209 ILE R CA  1 
ATOM 5626 C C   . ILE E 5 273 ? 148.447 163.723 118.007 1.00 115.36 ? 209 ILE R C   1 
ATOM 5627 O O   . ILE E 5 273 ? 148.772 162.615 118.439 1.00 120.51 ? 209 ILE R O   1 
ATOM 5628 C CB  . ILE E 5 273 ? 147.624 164.018 115.633 1.00 120.08 ? 209 ILE R CB  1 
ATOM 5629 C CG1 . ILE E 5 273 ? 146.416 163.780 114.724 1.00 122.28 ? 209 ILE R CG1 1 
ATOM 5630 C CG2 . ILE E 5 273 ? 148.741 163.048 115.291 1.00 114.05 ? 209 ILE R CG2 1 
ATOM 5631 C CD1 . ILE E 5 273 ? 146.737 163.876 113.246 1.00 121.73 ? 209 ILE R CD1 1 
ATOM 5632 N N   . ALA E 5 274 ? 149.146 164.823 118.296 1.00 103.88 ? 210 ALA R N   1 
ATOM 5633 C CA  . ALA E 5 274 ? 150.354 164.732 119.108 1.00 105.69 ? 210 ALA R CA  1 
ATOM 5634 C C   . ALA E 5 274 ? 150.043 164.218 120.507 1.00 113.02 ? 210 ALA R C   1 
ATOM 5635 O O   . ALA E 5 274 ? 150.816 163.432 121.071 1.00 117.58 ? 210 ALA R O   1 
ATOM 5636 C CB  . ALA E 5 274 ? 151.049 166.092 119.175 1.00 112.29 ? 210 ALA R CB  1 
ATOM 5637 N N   . LEU E 5 275 ? 148.906 164.628 121.076 1.00 113.28 ? 211 LEU R N   1 
ATOM 5638 C CA  . LEU E 5 275 ? 148.559 164.171 122.416 1.00 114.17 ? 211 LEU R CA  1 
ATOM 5639 C C   . LEU E 5 275 ? 148.081 162.728 122.407 1.00 111.91 ? 211 LEU R C   1 
ATOM 5640 O O   . LEU E 5 275 ? 148.562 161.911 123.193 1.00 109.12 ? 211 LEU R O   1 
ATOM 5641 C CB  . LEU E 5 275 ? 147.492 165.077 123.026 1.00 114.21 ? 211 LEU R CB  1 
ATOM 5642 C CG  . LEU E 5 275 ? 147.916 166.506 123.357 1.00 117.30 ? 211 LEU R CG  1 
ATOM 5643 C CD1 . LEU E 5 275 ? 146.781 167.252 124.046 1.00 117.13 ? 211 LEU R CD1 1 
ATOM 5644 C CD2 . LEU E 5 275 ? 149.169 166.502 124.217 1.00 116.63 ? 211 LEU R CD2 1 
ATOM 5645 N N   . MET E 5 276 ? 147.140 162.389 121.526 1.00 124.19 ? 212 MET R N   1 
ATOM 5646 C CA  . MET E 5 276 ? 146.594 161.035 121.535 1.00 126.55 ? 212 MET R CA  1 
ATOM 5647 C C   . MET E 5 276 ? 147.636 160.008 121.109 1.00 128.07 ? 212 MET R C   1 
ATOM 5648 O O   . MET E 5 276 ? 147.683 158.899 121.653 1.00 125.86 ? 212 MET R O   1 
ATOM 5649 C CB  . MET E 5 276 ? 145.365 160.961 120.629 1.00 130.92 ? 212 MET R CB  1 
ATOM 5650 C CG  . MET E 5 276 ? 144.201 161.844 121.067 1.00 131.40 ? 212 MET R CG  1 
ATOM 5651 S SD  . MET E 5 276 ? 142.790 161.755 119.941 1.00 138.36 ? 212 MET R SD  1 
ATOM 5652 C CE  . MET E 5 276 ? 141.635 162.878 120.726 1.00 127.44 ? 212 MET R CE  1 
ATOM 5653 N N   . VAL E 5 277 ? 148.480 160.351 120.138 1.00 114.76 ? 213 VAL R N   1 
ATOM 5654 C CA  . VAL E 5 277 ? 149.412 159.378 119.592 1.00 105.69 ? 213 VAL R CA  1 
ATOM 5655 C C   . VAL E 5 277 ? 150.675 159.302 120.435 1.00 96.34  ? 213 VAL R C   1 
ATOM 5656 O O   . VAL E 5 277 ? 151.173 158.205 120.718 1.00 100.25 ? 213 VAL R O   1 
ATOM 5657 C CB  . VAL E 5 277 ? 149.729 159.724 118.125 1.00 109.85 ? 213 VAL R CB  1 
ATOM 5658 C CG1 . VAL E 5 277 ? 150.826 158.818 117.585 1.00 111.45 ? 213 VAL R CG1 1 
ATOM 5659 C CG2 . VAL E 5 277 ? 148.476 159.608 117.277 1.00 112.03 ? 213 VAL R CG2 1 
ATOM 5660 N N   . PHE E 5 278 ? 151.225 160.449 120.852 1.00 83.26  ? 214 PHE R N   1 
ATOM 5661 C CA  . PHE E 5 278 ? 152.536 160.445 121.482 1.00 82.65  ? 214 PHE R CA  1 
ATOM 5662 C C   . PHE E 5 278 ? 152.517 160.860 122.948 1.00 92.72  ? 214 PHE R C   1 
ATOM 5663 O O   . PHE E 5 278 ? 152.854 160.047 123.808 1.00 99.44  ? 214 PHE R O   1 
ATOM 5664 C CB  . PHE E 5 278 ? 153.483 161.362 120.695 1.00 95.26  ? 214 PHE R CB  1 
ATOM 5665 C CG  . PHE E 5 278 ? 154.899 161.316 121.178 1.00 95.56  ? 214 PHE R CG  1 
ATOM 5666 C CD1 . PHE E 5 278 ? 155.749 160.301 120.771 1.00 95.27  ? 214 PHE R CD1 1 
ATOM 5667 C CD2 . PHE E 5 278 ? 155.382 162.285 122.037 1.00 97.10  ? 214 PHE R CD2 1 
ATOM 5668 C CE1 . PHE E 5 278 ? 157.055 160.255 121.213 1.00 100.23 ? 214 PHE R CE1 1 
ATOM 5669 C CE2 . PHE E 5 278 ? 156.686 162.246 122.484 1.00 96.17  ? 214 PHE R CE2 1 
ATOM 5670 C CZ  . PHE E 5 278 ? 157.524 161.230 122.071 1.00 100.44 ? 214 PHE R CZ  1 
ATOM 5671 N N   . VAL E 5 279 ? 152.090 162.084 123.270 1.00 93.54  ? 215 VAL R N   1 
ATOM 5672 C CA  . VAL E 5 279 ? 152.394 162.649 124.586 1.00 90.51  ? 215 VAL R CA  1 
ATOM 5673 C C   . VAL E 5 279 ? 151.551 161.990 125.672 1.00 94.55  ? 215 VAL R C   1 
ATOM 5674 O O   . VAL E 5 279 ? 152.080 161.515 126.685 1.00 98.94  ? 215 VAL R O   1 
ATOM 5675 C CB  . VAL E 5 279 ? 152.200 164.175 124.574 1.00 94.50  ? 215 VAL R CB  1 
ATOM 5676 C CG1 . VAL E 5 279 ? 152.319 164.732 125.981 1.00 99.98  ? 215 VAL R CG1 1 
ATOM 5677 C CG2 . VAL E 5 279 ? 153.218 164.823 123.656 1.00 98.65  ? 215 VAL R CG2 1 
ATOM 5678 N N   . ALA E 5 280 ? 150.230 161.980 125.497 1.00 102.98 ? 216 ALA R N   1 
ATOM 5679 C CA  . ALA E 5 280 ? 149.367 161.374 126.510 1.00 106.37 ? 216 ALA R CA  1 
ATOM 5680 C C   . ALA E 5 280 ? 149.662 159.896 126.723 1.00 106.06 ? 216 ALA R C   1 
ATOM 5681 O O   . ALA E 5 280 ? 149.780 159.482 127.888 1.00 106.51 ? 216 ALA R O   1 
ATOM 5682 C CB  . ALA E 5 280 ? 147.894 161.606 126.159 1.00 103.35 ? 216 ALA R CB  1 
ATOM 5683 N N   . PRO E 5 281 ? 149.782 159.051 125.689 1.00 101.88 ? 217 PRO R N   1 
ATOM 5684 C CA  . PRO E 5 281 ? 150.171 157.660 125.952 1.00 95.16  ? 217 PRO R CA  1 
ATOM 5685 C C   . PRO E 5 281 ? 151.586 157.514 126.464 1.00 96.26  ? 217 PRO R C   1 
ATOM 5686 O O   . PRO E 5 281 ? 151.847 156.565 127.203 1.00 105.84 ? 217 PRO R O   1 
ATOM 5687 C CB  . PRO E 5 281 ? 149.994 156.976 124.593 1.00 99.83  ? 217 PRO R CB  1 
ATOM 5688 C CG  . PRO E 5 281 ? 150.156 158.052 123.626 1.00 106.72 ? 217 PRO R CG  1 
ATOM 5689 C CD  . PRO E 5 281 ? 149.556 159.267 124.252 1.00 107.41 ? 217 PRO R CD  1 
ATOM 5690 N N   . THR E 5 282 ? 152.508 158.418 126.126 1.00 88.71  ? 218 THR R N   1 
ATOM 5691 C CA  . THR E 5 282 ? 153.847 158.327 126.699 1.00 93.92  ? 218 THR R CA  1 
ATOM 5692 C C   . THR E 5 282 ? 153.812 158.571 128.200 1.00 102.01 ? 218 THR R C   1 
ATOM 5693 O O   . THR E 5 282 ? 154.400 157.811 128.974 1.00 107.53 ? 218 THR R O   1 
ATOM 5694 C CB  . THR E 5 282 ? 154.800 159.313 126.021 1.00 96.05  ? 218 THR R CB  1 
ATOM 5695 O OG1 . THR E 5 282 ? 155.170 158.814 124.730 1.00 110.16 ? 218 THR R OG1 1 
ATOM 5696 C CG2 . THR E 5 282 ? 156.056 159.503 126.855 1.00 88.31  ? 218 THR R CG2 1 
ATOM 5697 N N   . LEU E 5 283 ? 153.106 159.614 128.633 1.00 111.45 ? 219 LEU R N   1 
ATOM 5698 C CA  . LEU E 5 283 ? 153.002 159.876 130.067 1.00 114.54 ? 219 LEU R CA  1 
ATOM 5699 C C   . LEU E 5 283 ? 152.179 158.801 130.770 1.00 113.97 ? 219 LEU R C   1 
ATOM 5700 O O   . LEU E 5 283 ? 152.504 158.400 131.894 1.00 115.00 ? 219 LEU R O   1 
ATOM 5701 C CB  . LEU E 5 283 ? 152.412 161.265 130.311 1.00 110.80 ? 219 LEU R CB  1 
ATOM 5702 C CG  . LEU E 5 283 ? 153.348 162.440 130.011 1.00 111.61 ? 219 LEU R CG  1 
ATOM 5703 C CD1 . LEU E 5 283 ? 152.653 163.768 130.267 1.00 109.67 ? 219 LEU R CD1 1 
ATOM 5704 C CD2 . LEU E 5 283 ? 154.624 162.337 130.831 1.00 110.83 ? 219 LEU R CD2 1 
ATOM 5705 N N   . GLY E 5 284 ? 151.117 158.312 130.126 1.00 90.01  ? 220 GLY R N   1 
ATOM 5706 C CA  . GLY E 5 284 ? 150.339 157.239 130.721 1.00 84.34  ? 220 GLY R CA  1 
ATOM 5707 C C   . GLY E 5 284 ? 151.149 155.970 130.893 1.00 88.85  ? 220 GLY R C   1 
ATOM 5708 O O   . GLY E 5 284 ? 151.095 155.320 131.938 1.00 94.08  ? 220 GLY R O   1 
ATOM 5709 N N   . ILE E 5 285 ? 151.911 155.599 129.863 1.00 92.73  ? 221 ILE R N   1 
ATOM 5710 C CA  . ILE E 5 285 ? 152.741 154.409 129.936 1.00 93.72  ? 221 ILE R CA  1 
ATOM 5711 C C   . ILE E 5 285 ? 153.886 154.621 130.913 1.00 100.14 ? 221 ILE R C   1 
ATOM 5712 O O   . ILE E 5 285 ? 154.342 153.670 131.549 1.00 111.16 ? 221 ILE R O   1 
ATOM 5713 C CB  . ILE E 5 285 ? 153.231 154.018 128.527 1.00 91.05  ? 221 ILE R CB  1 
ATOM 5714 C CG1 . ILE E 5 285 ? 153.437 152.510 128.430 1.00 99.09  ? 221 ILE R CG1 1 
ATOM 5715 C CG2 . ILE E 5 285 ? 154.514 154.749 128.152 1.00 92.00  ? 221 ILE R CG2 1 
ATOM 5716 C CD1 . ILE E 5 285 ? 153.626 152.026 127.015 1.00 110.94 ? 221 ILE R CD1 1 
ATOM 5717 N N   . ALA E 5 286 ? 154.360 155.856 131.069 1.00 87.53  ? 222 ALA R N   1 
ATOM 5718 C CA  . ALA E 5 286 ? 155.351 156.120 132.103 1.00 89.64  ? 222 ALA R CA  1 
ATOM 5719 C C   . ALA E 5 286 ? 154.758 155.905 133.486 1.00 95.25  ? 222 ALA R C   1 
ATOM 5720 O O   . ALA E 5 286 ? 155.396 155.303 134.356 1.00 101.33 ? 222 ALA R O   1 
ATOM 5721 C CB  . ALA E 5 286 ? 155.893 157.541 131.966 1.00 91.65  ? 222 ALA R CB  1 
ATOM 5722 N N   . ALA E 5 287 ? 153.533 156.383 133.702 1.00 89.58  ? 223 ALA R N   1 
ATOM 5723 C CA  . ALA E 5 287 ? 152.869 156.169 134.984 1.00 95.15  ? 223 ALA R CA  1 
ATOM 5724 C C   . ALA E 5 287 ? 152.629 154.687 135.234 1.00 92.82  ? 223 ALA R C   1 
ATOM 5725 O O   . ALA E 5 287 ? 152.806 154.197 136.356 1.00 91.19  ? 223 ALA R O   1 
ATOM 5726 C CB  . ALA E 5 287 ? 151.552 156.942 135.027 1.00 92.68  ? 223 ALA R CB  1 
ATOM 5727 N N   . CYS E 5 288 ? 152.225 153.956 134.196 1.00 84.39  ? 224 CYS R N   1 
ATOM 5728 C CA  . CYS E 5 288 ? 152.001 152.522 134.337 1.00 86.29  ? 224 CYS R CA  1 
ATOM 5729 C C   . CYS E 5 288 ? 153.303 151.779 134.608 1.00 89.81  ? 224 CYS R C   1 
ATOM 5730 O O   . CYS E 5 288 ? 153.321 150.819 135.377 1.00 95.04  ? 224 CYS R O   1 
ATOM 5731 C CB  . CYS E 5 288 ? 151.312 151.972 133.089 1.00 85.33  ? 224 CYS R CB  1 
ATOM 5732 S SG  . CYS E 5 288 ? 149.644 152.615 132.818 1.00 111.64 ? 224 CYS R SG  1 
ATOM 5733 N N   . GLN E 5 289 ? 154.403 152.196 133.983 1.00 89.20  ? 225 GLN R N   1 
ATOM 5734 C CA  . GLN E 5 289 ? 155.687 151.566 134.266 1.00 89.06  ? 225 GLN R CA  1 
ATOM 5735 C C   . GLN E 5 289 ? 156.166 151.888 135.673 1.00 92.81  ? 225 GLN R C   1 
ATOM 5736 O O   . GLN E 5 289 ? 156.829 151.058 136.310 1.00 103.60 ? 225 GLN R O   1 
ATOM 5737 C CB  . GLN E 5 289 ? 156.727 152.005 133.237 1.00 89.12  ? 225 GLN R CB  1 
ATOM 5738 C CG  . GLN E 5 289 ? 156.518 151.410 131.853 1.00 92.15  ? 225 GLN R CG  1 
ATOM 5739 C CD  . GLN E 5 289 ? 156.959 149.965 131.771 1.00 90.45  ? 225 GLN R CD  1 
ATOM 5740 O OE1 . GLN E 5 289 ? 157.738 149.497 132.599 1.00 89.67  ? 225 GLN R OE1 1 
ATOM 5741 N NE2 . GLN E 5 289 ? 156.465 149.249 130.767 1.00 94.05  ? 225 GLN R NE2 1 
ATOM 5742 N N   . VAL E 5 290 ? 155.857 153.085 136.170 1.00 84.52  ? 226 VAL R N   1 
ATOM 5743 C CA  . VAL E 5 290 ? 156.151 153.391 137.565 1.00 85.82  ? 226 VAL R CA  1 
ATOM 5744 C C   . VAL E 5 290 ? 155.318 152.506 138.483 1.00 89.76  ? 226 VAL R C   1 
ATOM 5745 O O   . VAL E 5 290 ? 155.805 152.031 139.511 1.00 92.70  ? 226 VAL R O   1 
ATOM 5746 C CB  . VAL E 5 290 ? 155.933 154.887 137.850 1.00 92.31  ? 226 VAL R CB  1 
ATOM 5747 C CG1 . VAL E 5 290 ? 156.033 155.164 139.344 1.00 92.18  ? 226 VAL R CG1 1 
ATOM 5748 C CG2 . VAL E 5 290 ? 156.959 155.712 137.097 1.00 98.28  ? 226 VAL R CG2 1 
ATOM 5749 N N   . LEU E 5 291 ? 154.058 152.251 138.118 1.00 94.35  ? 227 LEU R N   1 
ATOM 5750 C CA  . LEU E 5 291 ? 153.252 151.288 138.866 1.00 95.10  ? 227 LEU R CA  1 
ATOM 5751 C C   . LEU E 5 291 ? 153.842 149.882 138.782 1.00 100.23 ? 227 LEU R C   1 
ATOM 5752 O O   . LEU E 5 291 ? 153.752 149.098 139.735 1.00 104.34 ? 227 LEU R O   1 
ATOM 5753 C CB  . LEU E 5 291 ? 151.822 151.287 138.340 1.00 91.75  ? 227 LEU R CB  1 
ATOM 5754 C CG  . LEU E 5 291 ? 150.914 152.466 138.659 1.00 105.07 ? 227 LEU R CG  1 
ATOM 5755 C CD1 . LEU E 5 291 ? 149.785 152.542 137.640 1.00 107.10 ? 227 LEU R CD1 1 
ATOM 5756 C CD2 . LEU E 5 291 ? 150.345 152.306 140.039 1.00 103.86 ? 227 LEU R CD2 1 
ATOM 5757 N N   . ILE E 5 292 ? 154.423 149.538 137.632 1.00 93.37  ? 228 ILE R N   1 
ATOM 5758 C CA  . ILE E 5 292 ? 155.033 148.223 137.456 1.00 84.93  ? 228 ILE R CA  1 
ATOM 5759 C C   . ILE E 5 292 ? 156.219 148.060 138.393 1.00 84.53  ? 228 ILE R C   1 
ATOM 5760 O O   . ILE E 5 292 ? 156.361 147.038 139.071 1.00 98.16  ? 228 ILE R O   1 
ATOM 5761 C CB  . ILE E 5 292 ? 155.447 148.014 135.989 1.00 85.56  ? 228 ILE R CB  1 
ATOM 5762 C CG1 . ILE E 5 292 ? 154.276 147.456 135.182 1.00 89.49  ? 228 ILE R CG1 1 
ATOM 5763 C CG2 . ILE E 5 292 ? 156.647 147.091 135.902 1.00 88.65  ? 228 ILE R CG2 1 
ATOM 5764 C CD1 . ILE E 5 292 ? 154.563 147.354 133.707 1.00 98.96  ? 228 ILE R CD1 1 
ATOM 5765 N N   . PHE E 5 293 ? 157.093 149.060 138.441 1.00 75.88  ? 229 PHE R N   1 
ATOM 5766 C CA  . PHE E 5 293 ? 158.166 149.018 139.424 1.00 78.25  ? 229 PHE R CA  1 
ATOM 5767 C C   . PHE E 5 293 ? 157.623 149.108 140.842 1.00 88.93  ? 229 PHE R C   1 
ATOM 5768 O O   . PHE E 5 293 ? 158.244 148.588 141.766 1.00 99.33  ? 229 PHE R O   1 
ATOM 5769 C CB  . PHE E 5 293 ? 159.171 150.143 139.176 1.00 80.29  ? 229 PHE R CB  1 
ATOM 5770 C CG  . PHE E 5 293 ? 160.064 149.906 138.001 1.00 91.51  ? 229 PHE R CG  1 
ATOM 5771 C CD1 . PHE E 5 293 ? 161.164 149.084 138.113 1.00 87.89  ? 229 PHE R CD1 1 
ATOM 5772 C CD2 . PHE E 5 293 ? 159.802 150.507 136.783 1.00 99.07  ? 229 PHE R CD2 1 
ATOM 5773 C CE1 . PHE E 5 293 ? 161.987 148.858 137.030 1.00 92.08  ? 229 PHE R CE1 1 
ATOM 5774 C CE2 . PHE E 5 293 ? 160.617 150.289 135.699 1.00 93.03  ? 229 PHE R CE2 1 
ATOM 5775 C CZ  . PHE E 5 293 ? 161.715 149.464 135.821 1.00 91.11  ? 229 PHE R CZ  1 
ATOM 5776 N N   . ARG E 5 294 ? 156.480 149.774 141.028 1.00 101.29 ? 230 ARG R N   1 
ATOM 5777 C CA  . ARG E 5 294 ? 155.835 149.847 142.337 1.00 105.48 ? 230 ARG R CA  1 
ATOM 5778 C C   . ARG E 5 294 ? 155.492 148.457 142.851 1.00 103.47 ? 230 ARG R C   1 
ATOM 5779 O O   . ARG E 5 294 ? 155.775 148.113 144.011 1.00 108.77 ? 230 ARG R O   1 
ATOM 5780 C CB  . ARG E 5 294 ? 154.572 150.715 142.239 1.00 106.50 ? 230 ARG R CB  1 
ATOM 5781 C CG  . ARG E 5 294 ? 153.567 150.599 143.395 1.00 110.50 ? 230 ARG R CG  1 
ATOM 5782 C CD  . ARG E 5 294 ? 152.245 151.291 143.037 1.00 108.67 ? 230 ARG R CD  1 
ATOM 5783 N NE  . ARG E 5 294 ? 151.361 151.491 144.182 1.00 109.34 ? 230 ARG R NE  1 
ATOM 5784 C CZ  . ARG E 5 294 ? 150.123 151.968 144.107 1.00 107.22 ? 230 ARG R CZ  1 
ATOM 5785 N NH1 . ARG E 5 294 ? 149.570 152.282 142.951 1.00 106.92 ? 230 ARG R NH1 1 
ATOM 5786 N NH2 . ARG E 5 294 ? 149.419 152.125 145.222 1.00 104.11 ? 230 ARG R NH2 1 
ATOM 5787 N N   . GLU E 5 295 ? 154.891 147.637 141.994 1.00 87.93  ? 231 GLU R N   1 
ATOM 5788 C CA  . GLU E 5 295 ? 154.554 146.276 142.396 1.00 88.34  ? 231 GLU R CA  1 
ATOM 5789 C C   . GLU E 5 295 ? 155.775 145.368 142.424 1.00 89.06  ? 231 GLU R C   1 
ATOM 5790 O O   . GLU E 5 295 ? 155.873 144.500 143.296 1.00 94.16  ? 231 GLU R O   1 
ATOM 5791 C CB  . GLU E 5 295 ? 153.483 145.693 141.481 1.00 89.22  ? 231 GLU R CB  1 
ATOM 5792 C CG  . GLU E 5 295 ? 152.103 146.250 141.737 1.00 99.18  ? 231 GLU R CG  1 
ATOM 5793 C CD  . GLU E 5 295 ? 151.620 145.986 143.147 1.00 105.52 ? 231 GLU R CD  1 
ATOM 5794 O OE1 . GLU E 5 295 ? 152.053 144.985 143.753 1.00 107.68 ? 231 GLU R OE1 1 
ATOM 5795 O OE2 . GLU E 5 295 ? 150.801 146.783 143.649 1.00 105.81 ? 231 GLU R OE2 1 
ATOM 5796 N N   . ILE E 5 296 ? 156.709 145.539 141.487 1.00 82.67  ? 232 ILE R N   1 
ATOM 5797 C CA  . ILE E 5 296 ? 157.917 144.720 141.488 1.00 78.92  ? 232 ILE R CA  1 
ATOM 5798 C C   . ILE E 5 296 ? 158.732 144.991 142.744 1.00 85.28  ? 232 ILE R C   1 
ATOM 5799 O O   . ILE E 5 296 ? 159.155 144.066 143.442 1.00 94.67  ? 232 ILE R O   1 
ATOM 5800 C CB  . ILE E 5 296 ? 158.740 144.977 140.211 1.00 78.05  ? 232 ILE R CB  1 
ATOM 5801 C CG1 . ILE E 5 296 ? 158.230 144.119 139.054 1.00 79.11  ? 232 ILE R CG1 1 
ATOM 5802 C CG2 . ILE E 5 296 ? 160.213 144.711 140.450 1.00 76.57  ? 232 ILE R CG2 1 
ATOM 5803 C CD1 . ILE E 5 296 ? 158.835 144.483 137.714 1.00 81.42  ? 232 ILE R CD1 1 
ATOM 5804 N N   . HIS E 5 297 ? 158.932 146.271 143.067 1.00 95.53  ? 233 HIS R N   1 
ATOM 5805 C CA  . HIS E 5 297 ? 159.753 146.661 144.203 1.00 101.72 ? 233 HIS R CA  1 
ATOM 5806 C C   . HIS E 5 297 ? 159.126 146.223 145.517 1.00 103.61 ? 233 HIS R C   1 
ATOM 5807 O O   . HIS E 5 297 ? 159.835 145.774 146.425 1.00 101.99 ? 233 HIS R O   1 
ATOM 5808 C CB  . HIS E 5 297 ? 159.966 148.176 144.185 1.00 103.70 ? 233 HIS R CB  1 
ATOM 5809 N N   . ALA E 5 298 ? 157.798 146.346 145.629 1.00 114.02 ? 234 ALA R N   1 
ATOM 5810 C CA  . ALA E 5 298 ? 157.078 146.013 146.860 1.00 115.06 ? 234 ALA R CA  1 
ATOM 5811 C C   . ALA E 5 298 ? 157.434 144.634 147.409 1.00 113.03 ? 234 ALA R C   1 
ATOM 5812 O O   . ALA E 5 298 ? 157.253 144.362 148.595 1.00 105.59 ? 234 ALA R O   1 
ATOM 5813 C CB  . ALA E 5 298 ? 155.578 146.102 146.613 1.00 114.80 ? 234 ALA R CB  1 
ATOM 5814 N N   . ALA E 5 328 ? 162.725 135.910 137.241 1.00 93.28  ? 264 ALA R N   1 
ATOM 5815 C CA  . ALA E 5 328 ? 161.980 137.151 137.078 1.00 86.39  ? 264 ALA R CA  1 
ATOM 5816 C C   . ALA E 5 328 ? 161.566 137.330 135.623 1.00 89.01  ? 264 ALA R C   1 
ATOM 5817 O O   . ALA E 5 328 ? 161.986 138.277 134.958 1.00 97.02  ? 264 ALA R O   1 
ATOM 5818 C CB  . ALA E 5 328 ? 162.808 138.334 137.548 1.00 91.31  ? 264 ALA R CB  1 
ATOM 5819 N N   . ALA E 5 329 ? 160.740 136.400 135.137 1.00 81.88  ? 265 ALA R N   1 
ATOM 5820 C CA  . ALA E 5 329 ? 160.280 136.464 133.754 1.00 85.42  ? 265 ALA R CA  1 
ATOM 5821 C C   . ALA E 5 329 ? 159.471 137.729 133.499 1.00 98.97  ? 265 ALA R C   1 
ATOM 5822 O O   . ALA E 5 329 ? 159.603 138.357 132.442 1.00 111.66 ? 265 ALA R O   1 
ATOM 5823 C CB  . ALA E 5 329 ? 159.460 135.219 133.416 1.00 89.16  ? 265 ALA R CB  1 
ATOM 5824 N N   . VAL E 5 330 ? 158.624 138.118 134.456 1.00 78.26  ? 266 VAL R N   1 
ATOM 5825 C CA  . VAL E 5 330 ? 157.838 139.336 134.288 1.00 74.39  ? 266 VAL R CA  1 
ATOM 5826 C C   . VAL E 5 330 ? 158.742 140.561 134.288 1.00 84.93  ? 266 VAL R C   1 
ATOM 5827 O O   . VAL E 5 330 ? 158.506 141.515 133.544 1.00 90.74  ? 266 VAL R O   1 
ATOM 5828 C CB  . VAL E 5 330 ? 156.746 139.439 135.370 1.00 79.55  ? 266 VAL R CB  1 
ATOM 5829 C CG1 . VAL E 5 330 ? 155.989 140.748 135.234 1.00 80.86  ? 266 VAL R CG1 1 
ATOM 5830 C CG2 . VAL E 5 330 ? 155.787 138.274 135.259 1.00 92.91  ? 266 VAL R CG2 1 
ATOM 5831 N N   . ALA E 5 331 ? 159.781 140.567 135.125 1.00 81.64  ? 267 ALA R N   1 
ATOM 5832 C CA  . ALA E 5 331 ? 160.731 141.675 135.093 1.00 83.67  ? 267 ALA R CA  1 
ATOM 5833 C C   . ALA E 5 331 ? 161.435 141.756 133.742 1.00 87.16  ? 267 ALA R C   1 
ATOM 5834 O O   . ALA E 5 331 ? 161.652 142.852 133.210 1.00 93.07  ? 267 ALA R O   1 
ATOM 5835 C CB  . ALA E 5 331 ? 161.748 141.537 136.225 1.00 78.27  ? 267 ALA R CB  1 
ATOM 5836 N N   . LYS E 5 332 ? 161.793 140.604 133.169 1.00 78.01  ? 268 LYS R N   1 
ATOM 5837 C CA  . LYS E 5 332 ? 162.412 140.592 131.846 1.00 71.70  ? 268 LYS R CA  1 
ATOM 5838 C C   . LYS E 5 332 ? 161.462 141.131 130.784 1.00 72.04  ? 268 LYS R C   1 
ATOM 5839 O O   . LYS E 5 332 ? 161.861 141.929 129.926 1.00 93.70  ? 268 LYS R O   1 
ATOM 5840 C CB  . LYS E 5 332 ? 162.859 139.174 131.494 1.00 80.58  ? 268 LYS R CB  1 
ATOM 5841 N N   . THR E 5 333 ? 160.199 140.711 130.826 1.00 60.66  ? 269 THR R N   1 
ATOM 5842 C CA  . THR E 5 333 ? 159.238 141.198 129.842 1.00 75.96  ? 269 THR R CA  1 
ATOM 5843 C C   . THR E 5 333 ? 158.917 142.673 130.053 1.00 87.51  ? 269 THR R C   1 
ATOM 5844 O O   . THR E 5 333 ? 158.648 143.395 129.083 1.00 93.41  ? 269 THR R O   1 
ATOM 5845 C CB  . THR E 5 333 ? 157.979 140.346 129.890 1.00 79.09  ? 269 THR R CB  1 
ATOM 5846 O OG1 . THR E 5 333 ? 157.467 140.336 131.224 1.00 91.04  ? 269 THR R OG1 1 
ATOM 5847 C CG2 . THR E 5 333 ? 158.295 138.919 129.475 1.00 85.32  ? 269 THR R CG2 1 
ATOM 5848 N N   . VAL E 5 334 ? 158.999 143.146 131.299 1.00 77.77  ? 270 VAL R N   1 
ATOM 5849 C CA  . VAL E 5 334 ? 158.860 144.569 131.582 1.00 73.56  ? 270 VAL R CA  1 
ATOM 5850 C C   . VAL E 5 334 ? 160.014 145.345 130.969 1.00 77.96  ? 270 VAL R C   1 
ATOM 5851 O O   . VAL E 5 334 ? 159.823 146.426 130.404 1.00 77.08  ? 270 VAL R O   1 
ATOM 5852 C CB  . VAL E 5 334 ? 158.772 144.801 133.100 1.00 72.04  ? 270 VAL R CB  1 
ATOM 5853 C CG1 . VAL E 5 334 ? 159.078 146.258 133.435 1.00 78.85  ? 270 VAL R CG1 1 
ATOM 5854 C CG2 . VAL E 5 334 ? 157.401 144.401 133.622 1.00 80.17  ? 270 VAL R CG2 1 
ATOM 5855 N N   . ARG E 5 335 ? 161.231 144.814 131.087 1.00 76.20  ? 271 ARG R N   1 
ATOM 5856 C CA  . ARG E 5 335 ? 162.378 145.457 130.456 1.00 75.91  ? 271 ARG R CA  1 
ATOM 5857 C C   . ARG E 5 335 ? 162.224 145.502 128.942 1.00 78.20  ? 271 ARG R C   1 
ATOM 5858 O O   . ARG E 5 335 ? 162.565 146.505 128.305 1.00 86.89  ? 271 ARG R O   1 
ATOM 5859 C CB  . ARG E 5 335 ? 163.665 144.733 130.836 1.00 77.51  ? 271 ARG R CB  1 
ATOM 5860 C CG  . ARG E 5 335 ? 164.249 145.181 132.142 1.00 84.44  ? 271 ARG R CG  1 
ATOM 5861 C CD  . ARG E 5 335 ? 165.653 144.667 132.282 1.00 86.51  ? 271 ARG R CD  1 
ATOM 5862 N NE  . ARG E 5 335 ? 165.707 143.221 132.119 1.00 91.65  ? 271 ARG R NE  1 
ATOM 5863 C CZ  . ARG E 5 335 ? 165.545 142.350 133.106 1.00 90.24  ? 271 ARG R CZ  1 
ATOM 5864 N NH1 . ARG E 5 335 ? 165.304 142.746 134.345 1.00 90.03  ? 271 ARG R NH1 1 
ATOM 5865 N NH2 . ARG E 5 335 ? 165.628 141.049 132.843 1.00 82.91  ? 271 ARG R NH2 1 
ATOM 5866 N N   . MET E 5 336 ? 161.738 144.412 128.345 1.00 67.47  ? 272 MET R N   1 
ATOM 5867 C CA  . MET E 5 336 ? 161.482 144.413 126.907 1.00 70.42  ? 272 MET R CA  1 
ATOM 5868 C C   . MET E 5 336 ? 160.508 145.519 126.530 1.00 87.45  ? 272 MET R C   1 
ATOM 5869 O O   . MET E 5 336 ? 160.751 146.291 125.591 1.00 100.86 ? 272 MET R O   1 
ATOM 5870 C CB  . MET E 5 336 ? 160.928 143.061 126.465 1.00 72.65  ? 272 MET R CB  1 
ATOM 5871 C CG  . MET E 5 336 ? 160.537 143.006 125.001 1.00 82.35  ? 272 MET R CG  1 
ATOM 5872 S SD  . MET E 5 336 ? 159.453 141.609 124.655 1.00 95.38  ? 272 MET R SD  1 
ATOM 5873 C CE  . MET E 5 336 ? 157.982 142.085 125.561 1.00 70.42  ? 272 MET R CE  1 
ATOM 5874 N N   . THR E 5 337 ? 159.390 145.607 127.254 1.00 78.89  ? 273 THR R N   1 
ATOM 5875 C CA  . THR E 5 337 ? 158.420 146.655 126.959 1.00 81.48  ? 273 THR R CA  1 
ATOM 5876 C C   . THR E 5 337 ? 159.027 148.038 127.171 1.00 89.92  ? 273 THR R C   1 
ATOM 5877 O O   . THR E 5 337 ? 158.707 148.979 126.437 1.00 86.60  ? 273 THR R O   1 
ATOM 5878 C CB  . THR E 5 337 ? 157.166 146.468 127.818 1.00 76.29  ? 273 THR R CB  1 
ATOM 5879 O OG1 . THR E 5 337 ? 156.628 145.159 127.600 1.00 80.23  ? 273 THR R OG1 1 
ATOM 5880 C CG2 . THR E 5 337 ? 156.112 147.492 127.445 1.00 74.59  ? 273 THR R CG2 1 
ATOM 5881 N N   . LEU E 5 338 ? 159.911 148.175 128.160 1.00 79.48  ? 274 LEU R N   1 
ATOM 5882 C CA  . LEU E 5 338 ? 160.580 149.449 128.394 1.00 66.46  ? 274 LEU R CA  1 
ATOM 5883 C C   . LEU E 5 338 ? 161.458 149.839 127.216 1.00 66.35  ? 274 LEU R C   1 
ATOM 5884 O O   . LEU E 5 338 ? 161.479 151.004 126.805 1.00 73.77  ? 274 LEU R O   1 
ATOM 5885 C CB  . LEU E 5 338 ? 161.419 149.378 129.666 1.00 68.42  ? 274 LEU R CB  1 
ATOM 5886 C CG  . LEU E 5 338 ? 160.743 149.744 130.985 1.00 66.93  ? 274 LEU R CG  1 
ATOM 5887 C CD1 . LEU E 5 338 ? 161.757 149.713 132.116 1.00 71.89  ? 274 LEU R CD1 1 
ATOM 5888 C CD2 . LEU E 5 338 ? 160.088 151.110 130.888 1.00 79.60  ? 274 LEU R CD2 1 
ATOM 5889 N N   . VAL E 5 339 ? 162.213 148.882 126.679 1.00 67.14  ? 275 VAL R N   1 
ATOM 5890 C CA  . VAL E 5 339 ? 163.037 149.170 125.509 1.00 70.65  ? 275 VAL R CA  1 
ATOM 5891 C C   . VAL E 5 339 ? 162.156 149.569 124.336 1.00 76.37  ? 275 VAL R C   1 
ATOM 5892 O O   . VAL E 5 339 ? 162.489 150.480 123.567 1.00 80.09  ? 275 VAL R O   1 
ATOM 5893 C CB  . VAL E 5 339 ? 163.930 147.965 125.162 1.00 71.92  ? 275 VAL R CB  1 
ATOM 5894 C CG1 . VAL E 5 339 ? 164.756 148.262 123.925 1.00 69.13  ? 275 VAL R CG1 1 
ATOM 5895 C CG2 . VAL E 5 339 ? 164.834 147.620 126.331 1.00 79.04  ? 275 VAL R CG2 1 
ATOM 5896 N N   . ILE E 5 340 ? 161.012 148.900 124.188 1.00 63.51  ? 276 ILE R N   1 
ATOM 5897 C CA  . ILE E 5 340 ? 160.084 149.259 123.120 1.00 56.25  ? 276 ILE R CA  1 
ATOM 5898 C C   . ILE E 5 340 ? 159.601 150.694 123.290 1.00 64.49  ? 276 ILE R C   1 
ATOM 5899 O O   . ILE E 5 340 ? 159.550 151.467 122.324 1.00 72.29  ? 276 ILE R O   1 
ATOM 5900 C CB  . ILE E 5 340 ? 158.913 148.264 123.079 1.00 52.62  ? 276 ILE R CB  1 
ATOM 5901 C CG1 . ILE E 5 340 ? 159.430 146.867 122.731 1.00 69.15  ? 276 ILE R CG1 1 
ATOM 5902 C CG2 . ILE E 5 340 ? 157.871 148.714 122.079 1.00 61.03  ? 276 ILE R CG2 1 
ATOM 5903 C CD1 . ILE E 5 340 ? 158.342 145.865 122.411 1.00 66.21  ? 276 ILE R CD1 1 
ATOM 5904 N N   . VAL E 5 341 ? 159.251 151.076 124.521 1.00 70.57  ? 277 VAL R N   1 
ATOM 5905 C CA  . VAL E 5 341 ? 158.791 152.438 124.794 1.00 72.47  ? 277 VAL R CA  1 
ATOM 5906 C C   . VAL E 5 341 ? 159.882 153.449 124.469 1.00 75.89  ? 277 VAL R C   1 
ATOM 5907 O O   . VAL E 5 341 ? 159.625 154.496 123.865 1.00 78.38  ? 277 VAL R O   1 
ATOM 5908 C CB  . VAL E 5 341 ? 158.343 152.573 126.261 1.00 73.09  ? 277 VAL R CB  1 
ATOM 5909 C CG1 . VAL E 5 341 ? 157.996 154.019 126.582 1.00 77.92  ? 277 VAL R CG1 1 
ATOM 5910 C CG2 . VAL E 5 341 ? 157.170 151.676 126.545 1.00 71.95  ? 277 VAL R CG2 1 
ATOM 5911 N N   . VAL E 5 342 ? 161.111 153.165 124.901 1.00 81.06  ? 278 VAL R N   1 
ATOM 5912 C CA  . VAL E 5 342 ? 162.213 154.096 124.682 1.00 77.63  ? 278 VAL R CA  1 
ATOM 5913 C C   . VAL E 5 342 ? 162.460 154.289 123.193 1.00 79.29  ? 278 VAL R C   1 
ATOM 5914 O O   . VAL E 5 342 ? 162.643 155.419 122.720 1.00 80.21  ? 278 VAL R O   1 
ATOM 5915 C CB  . VAL E 5 342 ? 163.475 153.600 125.407 1.00 81.06  ? 278 VAL R CB  1 
ATOM 5916 C CG1 . VAL E 5 342 ? 164.682 154.404 124.985 1.00 79.42  ? 278 VAL R CG1 1 
ATOM 5917 C CG2 . VAL E 5 342 ? 163.279 153.694 126.900 1.00 85.73  ? 278 VAL R CG2 1 
ATOM 5918 N N   . VAL E 5 343 ? 162.464 153.194 122.431 1.00 74.36  ? 279 VAL R N   1 
ATOM 5919 C CA  . VAL E 5 343 ? 162.662 153.301 120.988 1.00 72.58  ? 279 VAL R CA  1 
ATOM 5920 C C   . VAL E 5 343 ? 161.523 154.085 120.350 1.00 73.94  ? 279 VAL R C   1 
ATOM 5921 O O   . VAL E 5 343 ? 161.746 154.920 119.464 1.00 84.61  ? 279 VAL R O   1 
ATOM 5922 C CB  . VAL E 5 343 ? 162.815 151.904 120.360 1.00 75.18  ? 279 VAL R CB  1 
ATOM 5923 C CG1 . VAL E 5 343 ? 162.828 152.007 118.847 1.00 74.72  ? 279 VAL R CG1 1 
ATOM 5924 C CG2 . VAL E 5 343 ? 164.093 151.247 120.849 1.00 82.91  ? 279 VAL R CG2 1 
ATOM 5925 N N   . TYR E 5 344 ? 160.286 153.827 120.780 1.00 82.77  ? 280 TYR R N   1 
ATOM 5926 C CA  . TYR E 5 344 ? 159.145 154.556 120.235 1.00 90.28  ? 280 TYR R CA  1 
ATOM 5927 C C   . TYR E 5 344 ? 159.279 156.052 120.489 1.00 93.78  ? 280 TYR R C   1 
ATOM 5928 O O   . TYR E 5 344 ? 159.080 156.873 119.582 1.00 100.51 ? 280 TYR R O   1 
ATOM 5929 C CB  . TYR E 5 344 ? 157.853 154.014 120.845 1.00 93.71  ? 280 TYR R CB  1 
ATOM 5930 C CG  . TYR E 5 344 ? 156.612 154.756 120.421 1.00 89.41  ? 280 TYR R CG  1 
ATOM 5931 C CD1 . TYR E 5 344 ? 155.948 154.422 119.253 1.00 85.79  ? 280 TYR R CD1 1 
ATOM 5932 C CD2 . TYR E 5 344 ? 156.098 155.784 121.196 1.00 95.41  ? 280 TYR R CD2 1 
ATOM 5933 C CE1 . TYR E 5 344 ? 154.812 155.097 118.865 1.00 91.04  ? 280 TYR R CE1 1 
ATOM 5934 C CE2 . TYR E 5 344 ? 154.965 156.464 120.816 1.00 94.97  ? 280 TYR R CE2 1 
ATOM 5935 C CZ  . TYR E 5 344 ? 154.327 156.118 119.649 1.00 93.72  ? 280 TYR R CZ  1 
ATOM 5936 O OH  . TYR E 5 344 ? 153.194 156.798 119.269 1.00 106.23 ? 280 TYR R OH  1 
ATOM 5937 N N   . VAL E 5 345 ? 159.626 156.424 121.721 1.00 82.28  ? 281 VAL R N   1 
ATOM 5938 C CA  . VAL E 5 345 ? 159.755 157.835 122.069 1.00 78.35  ? 281 VAL R CA  1 
ATOM 5939 C C   . VAL E 5 345 ? 160.868 158.483 121.258 1.00 78.30  ? 281 VAL R C   1 
ATOM 5940 O O   . VAL E 5 345 ? 160.698 159.574 120.703 1.00 79.57  ? 281 VAL R O   1 
ATOM 5941 C CB  . VAL E 5 345 ? 159.991 157.998 123.581 1.00 79.41  ? 281 VAL R CB  1 
ATOM 5942 C CG1 . VAL E 5 345 ? 160.414 159.420 123.900 1.00 77.44  ? 281 VAL R CG1 1 
ATOM 5943 C CG2 . VAL E 5 345 ? 158.735 157.630 124.357 1.00 84.83  ? 281 VAL R CG2 1 
ATOM 5944 N N   . LEU E 5 346 ? 162.021 157.816 121.166 1.00 89.48  ? 282 LEU R N   1 
ATOM 5945 C CA  . LEU E 5 346 ? 163.141 158.393 120.430 1.00 96.09  ? 282 LEU R CA  1 
ATOM 5946 C C   . LEU E 5 346 ? 162.806 158.564 118.956 1.00 97.27  ? 282 LEU R C   1 
ATOM 5947 O O   . LEU E 5 346 ? 163.174 159.572 118.343 1.00 99.96  ? 282 LEU R O   1 
ATOM 5948 C CB  . LEU E 5 346 ? 164.388 157.530 120.598 1.00 104.55 ? 282 LEU R CB  1 
ATOM 5949 C CG  . LEU E 5 346 ? 165.103 157.679 121.939 1.00 108.18 ? 282 LEU R CG  1 
ATOM 5950 C CD1 . LEU E 5 346 ? 166.351 156.819 121.978 1.00 106.46 ? 282 LEU R CD1 1 
ATOM 5951 C CD2 . LEU E 5 346 ? 165.446 159.135 122.184 1.00 102.19 ? 282 LEU R CD2 1 
ATOM 5952 N N   . CYS E 5 347 ? 162.108 157.592 118.367 1.00 97.20  ? 283 CYS R N   1 
ATOM 5953 C CA  . CYS E 5 347 ? 161.783 157.694 116.950 1.00 97.54  ? 283 CYS R CA  1 
ATOM 5954 C C   . CYS E 5 347 ? 160.756 158.786 116.689 1.00 100.49 ? 283 CYS R C   1 
ATOM 5955 O O   . CYS E 5 347 ? 160.859 159.511 115.693 1.00 103.22 ? 283 CYS R O   1 
ATOM 5956 C CB  . CYS E 5 347 ? 161.280 156.350 116.424 1.00 101.20 ? 283 CYS R CB  1 
ATOM 5957 N N   . TRP E 5 348 ? 159.762 158.931 117.564 1.00 94.31  ? 284 TRP R N   1 
ATOM 5958 C CA  . TRP E 5 348 ? 158.632 159.788 117.231 1.00 89.81  ? 284 TRP R CA  1 
ATOM 5959 C C   . TRP E 5 348 ? 158.665 161.169 117.874 1.00 96.61  ? 284 TRP R C   1 
ATOM 5960 O O   . TRP E 5 348 ? 157.817 161.998 117.533 1.00 102.99 ? 284 TRP R O   1 
ATOM 5961 C CB  . TRP E 5 348 ? 157.318 159.096 117.604 1.00 91.19  ? 284 TRP R CB  1 
ATOM 5962 C CG  . TRP E 5 348 ? 157.001 157.962 116.691 1.00 93.77  ? 284 TRP R CG  1 
ATOM 5963 C CD1 . TRP E 5 348 ? 157.517 156.705 116.743 1.00 104.47 ? 284 TRP R CD1 1 
ATOM 5964 C CD2 . TRP E 5 348 ? 156.105 157.984 115.576 1.00 93.27  ? 284 TRP R CD2 1 
ATOM 5965 N NE1 . TRP E 5 348 ? 156.995 155.937 115.732 1.00 104.14 ? 284 TRP R NE1 1 
ATOM 5966 C CE2 . TRP E 5 348 ? 156.123 156.700 115.001 1.00 102.17 ? 284 TRP R CE2 1 
ATOM 5967 C CE3 . TRP E 5 348 ? 155.286 158.963 115.010 1.00 99.54  ? 284 TRP R CE3 1 
ATOM 5968 C CZ2 . TRP E 5 348 ? 155.354 156.370 113.888 1.00 104.31 ? 284 TRP R CZ2 1 
ATOM 5969 C CZ3 . TRP E 5 348 ? 154.525 158.635 113.906 1.00 98.58  ? 284 TRP R CZ3 1 
ATOM 5970 C CH2 . TRP E 5 348 ? 154.563 157.350 113.357 1.00 97.35  ? 284 TRP R CH2 1 
ATOM 5971 N N   . ALA E 5 349 ? 159.595 161.442 118.790 1.00 105.50 ? 285 ALA R N   1 
ATOM 5972 C CA  . ALA E 5 349 ? 159.620 162.750 119.445 1.00 108.85 ? 285 ALA R CA  1 
ATOM 5973 C C   . ALA E 5 349 ? 159.766 163.923 118.479 1.00 111.80 ? 285 ALA R C   1 
ATOM 5974 O O   . ALA E 5 349 ? 158.940 164.853 118.546 1.00 118.02 ? 285 ALA R O   1 
ATOM 5975 C CB  . ALA E 5 349 ? 160.728 162.763 120.503 1.00 110.44 ? 285 ALA R CB  1 
ATOM 5976 N N   . PRO E 5 350 ? 160.756 163.961 117.577 1.00 111.88 ? 286 PRO R N   1 
ATOM 5977 C CA  . PRO E 5 350 ? 160.895 165.148 116.718 1.00 116.90 ? 286 PRO R CA  1 
ATOM 5978 C C   . PRO E 5 350 ? 159.747 165.319 115.750 1.00 120.47 ? 286 PRO R C   1 
ATOM 5979 O O   . PRO E 5 350 ? 159.440 166.454 115.367 1.00 128.02 ? 286 PRO R O   1 
ATOM 5980 C CB  . PRO E 5 350 ? 162.215 164.895 115.985 1.00 112.00 ? 286 PRO R CB  1 
ATOM 5981 C CG  . PRO E 5 350 ? 162.321 163.432 115.938 1.00 113.47 ? 286 PRO R CG  1 
ATOM 5982 C CD  . PRO E 5 350 ? 161.751 162.933 117.229 1.00 111.25 ? 286 PRO R CD  1 
ATOM 5983 N N   . PHE E 5 351 ? 159.083 164.223 115.383 1.00 99.64  ? 287 PHE R N   1 
ATOM 5984 C CA  . PHE E 5 351 ? 157.941 164.280 114.479 1.00 101.76 ? 287 PHE R CA  1 
ATOM 5985 C C   . PHE E 5 351 ? 156.881 165.237 115.008 1.00 104.55 ? 287 PHE R C   1 
ATOM 5986 O O   . PHE E 5 351 ? 156.595 166.280 114.405 1.00 113.39 ? 287 PHE R O   1 
ATOM 5987 C CB  . PHE E 5 351 ? 157.380 162.867 114.325 1.00 99.89  ? 287 PHE R CB  1 
ATOM 5988 C CG  . PHE E 5 351 ? 156.478 162.674 113.145 1.00 101.66 ? 287 PHE R CG  1 
ATOM 5989 C CD1 . PHE E 5 351 ? 155.156 163.079 113.184 1.00 105.55 ? 287 PHE R CD1 1 
ATOM 5990 C CD2 . PHE E 5 351 ? 156.942 162.033 112.015 1.00 109.58 ? 287 PHE R CD2 1 
ATOM 5991 C CE1 . PHE E 5 351 ? 154.325 162.873 112.101 1.00 110.76 ? 287 PHE R CE1 1 
ATOM 5992 C CE2 . PHE E 5 351 ? 156.118 161.823 110.937 1.00 110.57 ? 287 PHE R CE2 1 
ATOM 5993 C CZ  . PHE E 5 351 ? 154.809 162.245 110.976 1.00 112.65 ? 287 PHE R CZ  1 
ATOM 5994 N N   . PHE E 5 352 ? 156.324 164.916 116.177 1.00 88.85  ? 288 PHE R N   1 
ATOM 5995 C CA  . PHE E 5 352 ? 155.288 165.757 116.761 1.00 95.70  ? 288 PHE R CA  1 
ATOM 5996 C C   . PHE E 5 352 ? 155.860 167.043 117.343 1.00 101.22 ? 288 PHE R C   1 
ATOM 5997 O O   . PHE E 5 352 ? 155.143 168.047 117.418 1.00 104.55 ? 288 PHE R O   1 
ATOM 5998 C CB  . PHE E 5 352 ? 154.514 164.967 117.813 1.00 96.47  ? 288 PHE R CB  1 
ATOM 5999 C CG  . PHE E 5 352 ? 153.887 163.714 117.271 1.00 95.95  ? 288 PHE R CG  1 
ATOM 6000 C CD1 . PHE E 5 352 ? 152.709 163.771 116.547 1.00 95.48  ? 288 PHE R CD1 1 
ATOM 6001 C CD2 . PHE E 5 352 ? 154.488 162.483 117.466 1.00 95.96  ? 288 PHE R CD2 1 
ATOM 6002 C CE1 . PHE E 5 352 ? 152.134 162.624 116.037 1.00 97.04  ? 288 PHE R CE1 1 
ATOM 6003 C CE2 . PHE E 5 352 ? 153.918 161.330 116.960 1.00 91.95  ? 288 PHE R CE2 1 
ATOM 6004 C CZ  . PHE E 5 352 ? 152.740 161.401 116.242 1.00 89.15  ? 288 PHE R CZ  1 
ATOM 6005 N N   . LEU E 5 353 ? 157.140 167.050 117.732 1.00 110.95 ? 289 LEU R N   1 
ATOM 6006 C CA  . LEU E 5 353 ? 157.765 168.305 118.139 1.00 110.64 ? 289 LEU R CA  1 
ATOM 6007 C C   . LEU E 5 353 ? 157.646 169.352 117.037 1.00 108.79 ? 289 LEU R C   1 
ATOM 6008 O O   . LEU E 5 353 ? 157.111 170.450 117.253 1.00 111.89 ? 289 LEU R O   1 
ATOM 6009 C CB  . LEU E 5 353 ? 159.233 168.065 118.497 1.00 108.13 ? 289 LEU R CB  1 
ATOM 6010 C CG  . LEU E 5 353 ? 160.110 169.308 118.687 1.00 111.17 ? 289 LEU R CG  1 
ATOM 6011 C CD1 . LEU E 5 353 ? 159.572 170.173 119.814 1.00 112.21 ? 289 LEU R CD1 1 
ATOM 6012 C CD2 . LEU E 5 353 ? 161.566 168.936 118.941 1.00 110.00 ? 289 LEU R CD2 1 
ATOM 6013 N N   . VAL E 5 354 ? 158.086 169.006 115.828 1.00 94.33  ? 290 VAL R N   1 
ATOM 6014 C CA  . VAL E 5 354 ? 158.039 169.981 114.750 1.00 96.57  ? 290 VAL R CA  1 
ATOM 6015 C C   . VAL E 5 354 ? 156.614 170.153 114.236 1.00 102.64 ? 290 VAL R C   1 
ATOM 6016 O O   . VAL E 5 354 ? 156.254 171.238 113.757 1.00 113.76 ? 290 VAL R O   1 
ATOM 6017 C CB  . VAL E 5 354 ? 159.026 169.595 113.640 1.00 100.32 ? 290 VAL R CB  1 
ATOM 6018 C CG1 . VAL E 5 354 ? 160.412 169.417 114.235 1.00 106.87 ? 290 VAL R CG1 1 
ATOM 6019 C CG2 . VAL E 5 354 ? 158.577 168.339 112.929 1.00 106.41 ? 290 VAL R CG2 1 
ATOM 6020 N N   . GLN E 5 355 ? 155.766 169.127 114.355 1.00 110.74 ? 291 GLN R N   1 
ATOM 6021 C CA  . GLN E 5 355 ? 154.371 169.299 113.959 1.00 115.45 ? 291 GLN R CA  1 
ATOM 6022 C C   . GLN E 5 355 ? 153.676 170.358 114.812 1.00 119.26 ? 291 GLN R C   1 
ATOM 6023 O O   . GLN E 5 355 ? 153.020 171.261 114.283 1.00 119.34 ? 291 GLN R O   1 
ATOM 6024 C CB  . GLN E 5 355 ? 153.629 167.966 114.033 1.00 118.38 ? 291 GLN R CB  1 
ATOM 6025 C CG  . GLN E 5 355 ? 153.856 167.058 112.830 1.00 118.10 ? 291 GLN R CG  1 
ATOM 6026 C CD  . GLN E 5 355 ? 153.257 167.621 111.553 1.00 120.57 ? 291 GLN R CD  1 
ATOM 6027 O OE1 . GLN E 5 355 ? 152.182 168.219 111.570 1.00 126.17 ? 291 GLN R OE1 1 
ATOM 6028 N NE2 . GLN E 5 355 ? 153.956 167.440 110.441 1.00 119.45 ? 291 GLN R NE2 1 
ATOM 6029 N N   . LEU E 5 356 ? 153.832 170.283 116.138 1.00 117.41 ? 292 LEU R N   1 
ATOM 6030 C CA  . LEU E 5 356 ? 153.265 171.309 117.010 1.00 118.34 ? 292 LEU R CA  1 
ATOM 6031 C C   . LEU E 5 356 ? 153.922 172.665 116.774 1.00 120.86 ? 292 LEU R C   1 
ATOM 6032 O O   . LEU E 5 356 ? 153.251 173.707 116.831 1.00 115.71 ? 292 LEU R O   1 
ATOM 6033 C CB  . LEU E 5 356 ? 153.408 170.890 118.473 1.00 114.69 ? 292 LEU R CB  1 
ATOM 6034 C CG  . LEU E 5 356 ? 152.642 169.654 118.948 1.00 117.30 ? 292 LEU R CG  1 
ATOM 6035 C CD1 . LEU E 5 356 ? 153.242 169.130 120.241 1.00 120.40 ? 292 LEU R CD1 1 
ATOM 6036 C CD2 . LEU E 5 356 ? 151.174 169.974 119.148 1.00 120.81 ? 292 LEU R CD2 1 
ATOM 6037 N N   . TRP E 5 357 ? 155.239 172.677 116.542 1.00 128.62 ? 293 TRP R N   1 
ATOM 6038 C CA  . TRP E 5 357 ? 155.911 173.920 116.183 1.00 124.16 ? 293 TRP R CA  1 
ATOM 6039 C C   . TRP E 5 357 ? 155.178 174.610 115.042 1.00 117.43 ? 293 TRP R C   1 
ATOM 6040 O O   . TRP E 5 357 ? 154.656 175.714 115.195 1.00 117.76 ? 293 TRP R O   1 
ATOM 6041 C CB  . TRP E 5 357 ? 157.369 173.636 115.807 1.00 125.97 ? 293 TRP R CB  1 
ATOM 6042 C CG  . TRP E 5 357 ? 158.345 173.737 116.954 1.00 127.17 ? 293 TRP R CG  1 
ATOM 6043 C CD1 . TRP E 5 357 ? 158.070 174.119 118.231 1.00 127.22 ? 293 TRP R CD1 1 
ATOM 6044 C CD2 . TRP E 5 357 ? 159.754 173.463 116.913 1.00 126.12 ? 293 TRP R CD2 1 
ATOM 6045 N NE1 . TRP E 5 357 ? 159.215 174.096 118.991 1.00 127.38 ? 293 TRP R NE1 1 
ATOM 6046 C CE2 . TRP E 5 357 ? 160.262 173.698 118.204 1.00 127.61 ? 293 TRP R CE2 1 
ATOM 6047 C CE3 . TRP E 5 357 ? 160.631 173.037 115.912 1.00 119.83 ? 293 TRP R CE3 1 
ATOM 6048 C CZ2 . TRP E 5 357 ? 161.606 173.523 118.521 1.00 125.56 ? 293 TRP R CZ2 1 
ATOM 6049 C CZ3 . TRP E 5 357 ? 161.968 172.864 116.228 1.00 119.52 ? 293 TRP R CZ3 1 
ATOM 6050 C CH2 . TRP E 5 357 ? 162.441 173.105 117.521 1.00 123.15 ? 293 TRP R CH2 1 
ATOM 6051 N N   . ALA E 5 358 ? 155.090 173.935 113.899 1.00 105.44 ? 294 ALA R N   1 
ATOM 6052 C CA  . ALA E 5 358 ? 154.376 174.511 112.766 1.00 106.45 ? 294 ALA R CA  1 
ATOM 6053 C C   . ALA E 5 358 ? 152.935 174.835 113.131 1.00 116.10 ? 294 ALA R C   1 
ATOM 6054 O O   . ALA E 5 358 ? 152.343 175.769 112.575 1.00 121.92 ? 294 ALA R O   1 
ATOM 6055 C CB  . ALA E 5 358 ? 154.422 173.551 111.575 1.00 106.94 ? 294 ALA R CB  1 
ATOM 6056 N N   . ALA E 5 359 ? 152.362 174.082 114.067 1.00 125.30 ? 295 ALA R N   1 
ATOM 6057 C CA  . ALA E 5 359 ? 150.969 174.285 114.448 1.00 129.13 ? 295 ALA R CA  1 
ATOM 6058 C C   . ALA E 5 359 ? 150.741 175.648 115.091 1.00 133.07 ? 295 ALA R C   1 
ATOM 6059 O O   . ALA E 5 359 ? 149.776 176.340 114.761 1.00 130.78 ? 295 ALA R O   1 
ATOM 6060 C CB  . ALA E 5 359 ? 150.528 173.178 115.391 1.00 127.49 ? 295 ALA R CB  1 
ATOM 6061 N N   . TRP E 5 360 ? 151.605 176.045 116.025 1.00 143.50 ? 296 TRP R N   1 
ATOM 6062 C CA  . TRP E 5 360 ? 151.391 177.315 116.711 1.00 143.33 ? 296 TRP R CA  1 
ATOM 6063 C C   . TRP E 5 360 ? 152.197 178.458 116.123 1.00 144.90 ? 296 TRP R C   1 
ATOM 6064 O O   . TRP E 5 360 ? 151.839 179.619 116.342 1.00 144.09 ? 296 TRP R O   1 
ATOM 6065 C CB  . TRP E 5 360 ? 151.720 177.196 118.196 1.00 140.05 ? 296 TRP R CB  1 
ATOM 6066 C CG  . TRP E 5 360 ? 150.775 176.329 118.957 1.00 141.26 ? 296 TRP R CG  1 
ATOM 6067 C CD1 . TRP E 5 360 ? 150.631 174.983 118.841 1.00 139.94 ? 296 TRP R CD1 1 
ATOM 6068 C CD2 . TRP E 5 360 ? 149.858 176.744 119.977 1.00 143.55 ? 296 TRP R CD2 1 
ATOM 6069 N NE1 . TRP E 5 360 ? 149.675 174.532 119.713 1.00 140.19 ? 296 TRP R NE1 1 
ATOM 6070 C CE2 . TRP E 5 360 ? 149.187 175.595 120.424 1.00 144.09 ? 296 TRP R CE2 1 
ATOM 6071 C CE3 . TRP E 5 360 ? 149.537 177.977 120.550 1.00 143.73 ? 296 TRP R CE3 1 
ATOM 6072 C CZ2 . TRP E 5 360 ? 148.213 175.639 121.414 1.00 145.02 ? 296 TRP R CZ2 1 
ATOM 6073 C CZ3 . TRP E 5 360 ? 148.570 178.018 121.534 1.00 142.67 ? 296 TRP R CZ3 1 
ATOM 6074 C CH2 . TRP E 5 360 ? 147.920 176.858 121.956 1.00 141.21 ? 296 TRP R CH2 1 
ATOM 6075 N N   . ASP E 5 361 ? 153.271 178.161 115.391 1.00 161.28 ? 297 ASP R N   1 
ATOM 6076 C CA  . ASP E 5 361 ? 154.098 179.182 114.748 1.00 162.52 ? 297 ASP R CA  1 
ATOM 6077 C C   . ASP E 5 361 ? 154.622 178.621 113.439 1.00 159.53 ? 297 ASP R C   1 
ATOM 6078 O O   . ASP E 5 361 ? 155.575 177.825 113.428 1.00 159.42 ? 297 ASP R O   1 
ATOM 6079 C CB  . ASP E 5 361 ? 155.255 179.640 115.629 1.00 160.54 ? 297 ASP R CB  1 
ATOM 6080 C CG  . ASP E 5 361 ? 156.102 180.699 114.961 1.00 158.00 ? 297 ASP R CG  1 
ATOM 6081 O OD1 . ASP E 5 361 ? 155.751 181.148 113.855 1.00 158.18 ? 297 ASP R OD1 1 
ATOM 6082 O OD2 . ASP E 5 361 ? 157.124 181.092 115.547 1.00 153.25 ? 297 ASP R OD2 1 
ATOM 6083 N N   . PRO E 5 362 ? 154.035 179.019 112.307 1.00 138.97 ? 298 PRO R N   1 
ATOM 6084 C CA  . PRO E 5 362 ? 154.471 178.564 110.986 1.00 138.65 ? 298 PRO R CA  1 
ATOM 6085 C C   . PRO E 5 362 ? 155.867 179.074 110.636 1.00 142.14 ? 298 PRO R C   1 
ATOM 6086 O O   . PRO E 5 362 ? 156.554 178.447 109.832 1.00 141.08 ? 298 PRO R O   1 
ATOM 6087 C CB  . PRO E 5 362 ? 153.421 179.164 110.041 1.00 138.58 ? 298 PRO R CB  1 
ATOM 6088 C CG  . PRO E 5 362 ? 152.271 179.547 110.915 1.00 136.09 ? 298 PRO R CG  1 
ATOM 6089 C CD  . PRO E 5 362 ? 152.878 179.919 112.227 1.00 135.36 ? 298 PRO R CD  1 
ATOM 6090 N N   . PRO E 5 370 ? 161.741 168.658 104.115 1.00 148.52 ? 306 PRO R N   1 
ATOM 6091 C CA  . PRO E 5 370 ? 162.681 167.921 104.960 1.00 149.90 ? 306 PRO R CA  1 
ATOM 6092 C C   . PRO E 5 370 ? 161.979 167.055 105.988 1.00 149.91 ? 306 PRO R C   1 
ATOM 6093 O O   . PRO E 5 370 ? 162.636 166.450 106.831 1.00 150.10 ? 306 PRO R O   1 
ATOM 6094 C CB  . PRO E 5 370 ? 163.477 169.030 105.643 1.00 147.86 ? 306 PRO R CB  1 
ATOM 6095 C CG  . PRO E 5 370 ? 162.569 170.184 105.655 1.00 147.61 ? 306 PRO R CG  1 
ATOM 6096 C CD  . PRO E 5 370 ? 161.796 170.105 104.377 1.00 147.17 ? 306 PRO R CD  1 
ATOM 6097 N N   . PHE E 5 371 ? 160.650 167.001 105.920 1.00 157.10 ? 307 PHE R N   1 
ATOM 6098 C CA  . PHE E 5 371 ? 159.905 166.132 106.820 1.00 159.03 ? 307 PHE R CA  1 
ATOM 6099 C C   . PHE E 5 371 ? 160.139 164.654 106.523 1.00 156.84 ? 307 PHE R C   1 
ATOM 6100 O O   . PHE E 5 371 ? 159.906 163.812 107.400 1.00 154.73 ? 307 PHE R O   1 
ATOM 6101 C CB  . PHE E 5 371 ? 158.416 166.455 106.736 1.00 157.80 ? 307 PHE R CB  1 
ATOM 6102 C CG  . PHE E 5 371 ? 157.643 166.032 107.942 1.00 157.54 ? 307 PHE R CG  1 
ATOM 6103 C CD1 . PHE E 5 371 ? 158.145 166.262 109.209 1.00 155.79 ? 307 PHE R CD1 1 
ATOM 6104 C CD2 . PHE E 5 371 ? 156.412 165.416 107.815 1.00 156.44 ? 307 PHE R CD2 1 
ATOM 6105 C CE1 . PHE E 5 371 ? 157.441 165.878 110.327 1.00 152.38 ? 307 PHE R CE1 1 
ATOM 6106 C CE2 . PHE E 5 371 ? 155.698 165.031 108.929 1.00 155.18 ? 307 PHE R CE2 1 
ATOM 6107 C CZ  . PHE E 5 371 ? 156.215 165.261 110.188 1.00 153.40 ? 307 PHE R CZ  1 
ATOM 6108 N N   . VAL E 5 372 ? 160.607 164.326 105.316 1.00 149.47 ? 308 VAL R N   1 
ATOM 6109 C CA  . VAL E 5 372 ? 160.749 162.933 104.903 1.00 146.59 ? 308 VAL R CA  1 
ATOM 6110 C C   . VAL E 5 372 ? 161.761 162.197 105.771 1.00 145.68 ? 308 VAL R C   1 
ATOM 6111 O O   . VAL E 5 372 ? 161.601 161.000 106.049 1.00 147.84 ? 308 VAL R O   1 
ATOM 6112 C CB  . VAL E 5 372 ? 161.117 162.870 103.406 1.00 150.54 ? 308 VAL R CB  1 
ATOM 6113 C CG1 . VAL E 5 372 ? 162.450 163.556 103.145 1.00 151.34 ? 308 VAL R CG1 1 
ATOM 6114 C CG2 . VAL E 5 372 ? 161.131 161.432 102.910 1.00 151.54 ? 308 VAL R CG2 1 
ATOM 6115 N N   . LEU E 5 373 ? 162.804 162.888 106.225 1.00 143.30 ? 309 LEU R N   1 
ATOM 6116 C CA  . LEU E 5 373 ? 163.753 162.253 107.130 1.00 146.81 ? 309 LEU R CA  1 
ATOM 6117 C C   . LEU E 5 373 ? 163.076 161.846 108.426 1.00 143.71 ? 309 LEU R C   1 
ATOM 6118 O O   . LEU E 5 373 ? 163.362 160.778 108.978 1.00 142.23 ? 309 LEU R O   1 
ATOM 6119 C CB  . LEU E 5 373 ? 164.921 163.187 107.409 1.00 150.98 ? 309 LEU R CB  1 
ATOM 6120 C CG  . LEU E 5 373 ? 165.655 163.661 106.164 1.00 149.29 ? 309 LEU R CG  1 
ATOM 6121 C CD1 . LEU E 5 373 ? 166.743 164.642 106.543 1.00 144.98 ? 309 LEU R CD1 1 
ATOM 6122 C CD2 . LEU E 5 373 ? 166.236 162.477 105.426 1.00 146.98 ? 309 LEU R CD2 1 
ATOM 6123 N N   . LEU E 5 374 ? 162.155 162.672 108.919 1.00 136.39 ? 310 LEU R N   1 
ATOM 6124 C CA  . LEU E 5 374 ? 161.454 162.307 110.140 1.00 136.27 ? 310 LEU R CA  1 
ATOM 6125 C C   . LEU E 5 374 ? 160.456 161.194 109.882 1.00 136.14 ? 310 LEU R C   1 
ATOM 6126 O O   . LEU E 5 374 ? 160.256 160.331 110.740 1.00 139.12 ? 310 LEU R O   1 
ATOM 6127 C CB  . LEU E 5 374 ? 160.763 163.528 110.743 1.00 135.89 ? 310 LEU R CB  1 
ATOM 6128 N N   . MET E 5 375 ? 159.829 161.180 108.709 1.00 141.07 ? 311 MET R N   1 
ATOM 6129 C CA  . MET E 5 375 ? 158.975 160.048 108.380 1.00 144.66 ? 311 MET R CA  1 
ATOM 6130 C C   . MET E 5 375 ? 159.771 158.748 108.391 1.00 146.02 ? 311 MET R C   1 
ATOM 6131 O O   . MET E 5 375 ? 159.315 157.736 108.934 1.00 143.30 ? 311 MET R O   1 
ATOM 6132 C CB  . MET E 5 375 ? 158.314 160.269 107.029 1.00 148.13 ? 311 MET R CB  1 
ATOM 6133 C CG  . MET E 5 375 ? 157.711 161.645 106.875 1.00 148.72 ? 311 MET R CG  1 
ATOM 6134 S SD  . MET E 5 375 ? 156.080 161.801 107.628 1.00 150.58 ? 311 MET R SD  1 
ATOM 6135 C CE  . MET E 5 375 ? 155.143 160.560 106.749 1.00 140.72 ? 311 MET R CE  1 
ATOM 6136 N N   . LEU E 5 376 ? 160.986 158.773 107.838 1.00 141.46 ? 312 LEU R N   1 
ATOM 6137 C CA  . LEU E 5 376 ? 161.824 157.577 107.816 1.00 134.36 ? 312 LEU R CA  1 
ATOM 6138 C C   . LEU E 5 376 ? 162.243 157.159 109.222 1.00 134.13 ? 312 LEU R C   1 
ATOM 6139 O O   . LEU E 5 376 ? 162.152 155.978 109.584 1.00 132.70 ? 312 LEU R O   1 
ATOM 6140 C CB  . LEU E 5 376 ? 163.053 157.824 106.943 1.00 137.76 ? 312 LEU R CB  1 
ATOM 6141 N N   . LEU E 5 377 ? 162.727 158.108 110.025 1.00 129.52 ? 313 LEU R N   1 
ATOM 6142 C CA  . LEU E 5 377 ? 163.162 157.755 111.372 1.00 128.84 ? 313 LEU R CA  1 
ATOM 6143 C C   . LEU E 5 377 ? 161.999 157.250 112.216 1.00 126.24 ? 313 LEU R C   1 
ATOM 6144 O O   . LEU E 5 377 ? 162.166 156.331 113.026 1.00 125.13 ? 313 LEU R O   1 
ATOM 6145 C CB  . LEU E 5 377 ? 163.840 158.948 112.037 1.00 130.47 ? 313 LEU R CB  1 
ATOM 6146 C CG  . LEU E 5 377 ? 165.115 159.367 111.309 1.00 127.67 ? 313 LEU R CG  1 
ATOM 6147 C CD1 . LEU E 5 377 ? 165.820 160.478 112.062 1.00 127.00 ? 313 LEU R CD1 1 
ATOM 6148 C CD2 . LEU E 5 377 ? 166.037 158.172 111.107 1.00 127.70 ? 313 LEU R CD2 1 
ATOM 6149 N N   . ALA E 5 378 ? 160.813 157.837 112.046 1.00 126.97 ? 314 ALA R N   1 
ATOM 6150 C CA  . ALA E 5 378 ? 159.642 157.347 112.761 1.00 125.84 ? 314 ALA R CA  1 
ATOM 6151 C C   . ALA E 5 378 ? 159.280 155.937 112.319 1.00 128.32 ? 314 ALA R C   1 
ATOM 6152 O O   . ALA E 5 378 ? 158.987 155.074 113.155 1.00 133.08 ? 314 ALA R O   1 
ATOM 6153 C CB  . ALA E 5 378 ? 158.462 158.294 112.548 1.00 128.55 ? 314 ALA R CB  1 
ATOM 6154 N N   . SER E 5 379 ? 159.306 155.679 111.009 1.00 123.68 ? 315 SER R N   1 
ATOM 6155 C CA  . SER E 5 379 ? 158.946 154.358 110.509 1.00 121.95 ? 315 SER R CA  1 
ATOM 6156 C C   . SER E 5 379 ? 159.983 153.303 110.859 1.00 119.21 ? 315 SER R C   1 
ATOM 6157 O O   . SER E 5 379 ? 159.672 152.109 110.812 1.00 117.90 ? 315 SER R O   1 
ATOM 6158 C CB  . SER E 5 379 ? 158.736 154.405 108.995 1.00 125.66 ? 315 SER R CB  1 
ATOM 6159 O OG  . SER E 5 379 ? 159.908 154.830 108.321 1.00 124.85 ? 315 SER R OG  1 
ATOM 6160 N N   . LEU E 5 380 ? 161.207 153.706 111.202 1.00 118.75 ? 316 LEU R N   1 
ATOM 6161 C CA  . LEU E 5 380 ? 162.189 152.721 111.641 1.00 119.11 ? 316 LEU R CA  1 
ATOM 6162 C C   . LEU E 5 380 ? 161.787 152.031 112.941 1.00 122.64 ? 316 LEU R C   1 
ATOM 6163 O O   . LEU E 5 380 ? 162.253 150.916 113.209 1.00 129.93 ? 316 LEU R O   1 
ATOM 6164 C CB  . LEU E 5 380 ? 163.557 153.378 111.801 1.00 120.40 ? 316 LEU R CB  1 
ATOM 6165 C CG  . LEU E 5 380 ? 164.232 153.800 110.498 1.00 122.54 ? 316 LEU R CG  1 
ATOM 6166 C CD1 . LEU E 5 380 ? 165.660 154.244 110.765 1.00 123.70 ? 316 LEU R CD1 1 
ATOM 6167 C CD2 . LEU E 5 380 ? 164.186 152.677 109.472 1.00 120.41 ? 316 LEU R CD2 1 
ATOM 6168 N N   . ASN E 5 381 ? 160.937 152.660 113.755 1.00 111.00 ? 317 ASN R N   1 
ATOM 6169 C CA  . ASN E 5 381 ? 160.511 152.039 115.007 1.00 109.89 ? 317 ASN R CA  1 
ATOM 6170 C C   . ASN E 5 381 ? 159.708 150.765 114.762 1.00 109.64 ? 317 ASN R C   1 
ATOM 6171 O O   . ASN E 5 381 ? 159.807 149.804 115.537 1.00 113.52 ? 317 ASN R O   1 
ATOM 6172 C CB  . ASN E 5 381 ? 159.700 153.035 115.833 1.00 112.54 ? 317 ASN R CB  1 
ATOM 6173 C CG  . ASN E 5 381 ? 159.027 152.392 117.027 1.00 113.50 ? 317 ASN R CG  1 
ATOM 6174 O OD1 . ASN E 5 381 ? 159.635 152.220 118.082 1.00 111.65 ? 317 ASN R OD1 1 
ATOM 6175 N ND2 . ASN E 5 381 ? 157.757 152.043 116.868 1.00 112.35 ? 317 ASN R ND2 1 
ATOM 6176 N N   . SER E 5 382 ? 158.894 150.741 113.700 1.00 128.84 ? 318 SER R N   1 
ATOM 6177 C CA  . SER E 5 382 ? 158.067 149.576 113.398 1.00 133.33 ? 318 SER R CA  1 
ATOM 6178 C C   . SER E 5 382 ? 158.879 148.399 112.879 1.00 134.08 ? 318 SER R C   1 
ATOM 6179 O O   . SER E 5 382 ? 158.325 147.303 112.738 1.00 136.18 ? 318 SER R O   1 
ATOM 6180 C CB  . SER E 5 382 ? 156.979 149.940 112.384 1.00 140.20 ? 318 SER R CB  1 
ATOM 6181 O OG  . SER E 5 382 ? 157.537 150.388 111.162 1.00 142.85 ? 318 SER R OG  1 
ATOM 6182 N N   . CYS E 5 383 ? 160.160 148.598 112.576 1.00 126.33 ? 319 CYS R N   1 
ATOM 6183 C CA  . CYS E 5 383 ? 161.066 147.488 112.321 1.00 126.73 ? 319 CYS R CA  1 
ATOM 6184 C C   . CYS E 5 383 ? 162.001 147.223 113.487 1.00 122.87 ? 319 CYS R C   1 
ATOM 6185 O O   . CYS E 5 383 ? 162.534 146.113 113.595 1.00 123.93 ? 319 CYS R O   1 
ATOM 6186 C CB  . CYS E 5 383 ? 161.902 147.745 111.063 1.00 126.20 ? 319 CYS R CB  1 
ATOM 6187 S SG  . CYS E 5 383 ? 163.421 148.690 111.345 1.00 137.79 ? 319 CYS R SG  1 
ATOM 6188 N N   . THR E 5 384 ? 162.212 148.213 114.357 1.00 109.36 ? 320 THR R N   1 
ATOM 6189 C CA  . THR E 5 384 ? 163.041 147.991 115.537 1.00 112.60 ? 320 THR R CA  1 
ATOM 6190 C C   . THR E 5 384 ? 162.309 147.156 116.585 1.00 113.48 ? 320 THR R C   1 
ATOM 6191 O O   . THR E 5 384 ? 162.902 146.254 117.189 1.00 115.56 ? 320 THR R O   1 
ATOM 6192 C CB  . THR E 5 384 ? 163.483 149.329 116.130 1.00 116.48 ? 320 THR R CB  1 
ATOM 6193 O OG1 . THR E 5 384 ? 164.137 150.110 115.121 1.00 116.91 ? 320 THR R OG1 1 
ATOM 6194 C CG2 . THR E 5 384 ? 164.448 149.109 117.288 1.00 112.69 ? 320 THR R CG2 1 
ATOM 6195 N N   . ASN E 5 385 ? 161.018 147.438 116.814 1.00 111.33 ? 321 ASN R N   1 
ATOM 6196 C CA  . ASN E 5 385 ? 160.233 146.730 117.828 1.00 110.74 ? 321 ASN R CA  1 
ATOM 6197 C C   . ASN E 5 385 ? 160.288 145.207 117.693 1.00 113.49 ? 321 ASN R C   1 
ATOM 6198 O O   . ASN E 5 385 ? 160.638 144.525 118.669 1.00 118.92 ? 321 ASN R O   1 
ATOM 6199 C CB  . ASN E 5 385 ? 158.768 147.182 117.794 1.00 109.37 ? 321 ASN R CB  1 
ATOM 6200 N N   . PRO E 5 386 ? 159.952 144.626 116.530 1.00 111.90 ? 322 PRO R N   1 
ATOM 6201 C CA  . PRO E 5 386 ? 159.911 143.157 116.455 1.00 114.52 ? 322 PRO R CA  1 
ATOM 6202 C C   . PRO E 5 386 ? 161.246 142.502 116.724 1.00 113.54 ? 322 PRO R C   1 
ATOM 6203 O O   . PRO E 5 386 ? 161.279 141.396 117.272 1.00 118.05 ? 322 PRO R O   1 
ATOM 6204 C CB  . PRO E 5 386 ? 159.430 142.895 115.024 1.00 115.05 ? 322 PRO R CB  1 
ATOM 6205 C CG  . PRO E 5 386 ? 159.915 144.064 114.268 1.00 114.48 ? 322 PRO R CG  1 
ATOM 6206 C CD  . PRO E 5 386 ? 159.711 145.223 115.204 1.00 112.98 ? 322 PRO R CD  1 
ATOM 6207 N N   . TRP E 5 387 ? 162.358 143.157 116.391 1.00 105.28 ? 323 TRP R N   1 
ATOM 6208 C CA  . TRP E 5 387 ? 163.651 142.556 116.692 1.00 108.65 ? 323 TRP R CA  1 
ATOM 6209 C C   . TRP E 5 387 ? 164.009 142.669 118.166 1.00 113.91 ? 323 TRP R C   1 
ATOM 6210 O O   . TRP E 5 387 ? 164.664 141.772 118.700 1.00 118.96 ? 323 TRP R O   1 
ATOM 6211 C CB  . TRP E 5 387 ? 164.742 143.178 115.834 1.00 112.37 ? 323 TRP R CB  1 
ATOM 6212 C CG  . TRP E 5 387 ? 164.680 142.729 114.418 1.00 120.34 ? 323 TRP R CG  1 
ATOM 6213 C CD1 . TRP E 5 387 ? 163.740 141.915 113.859 1.00 121.09 ? 323 TRP R CD1 1 
ATOM 6214 C CD2 . TRP E 5 387 ? 165.595 143.063 113.372 1.00 118.51 ? 323 TRP R CD2 1 
ATOM 6215 N NE1 . TRP E 5 387 ? 164.013 141.721 112.527 1.00 116.51 ? 323 TRP R NE1 1 
ATOM 6216 C CE2 . TRP E 5 387 ? 165.147 142.418 112.203 1.00 117.48 ? 323 TRP R CE2 1 
ATOM 6217 C CE3 . TRP E 5 387 ? 166.750 143.846 113.310 1.00 112.21 ? 323 TRP R CE3 1 
ATOM 6218 C CZ2 . TRP E 5 387 ? 165.813 142.533 110.986 1.00 116.84 ? 323 TRP R CZ2 1 
ATOM 6219 C CZ3 . TRP E 5 387 ? 167.409 143.959 112.102 1.00 111.62 ? 323 TRP R CZ3 1 
ATOM 6220 C CH2 . TRP E 5 387 ? 166.940 143.306 110.957 1.00 117.00 ? 323 TRP R CH2 1 
ATOM 6221 N N   . ILE E 5 388 ? 163.571 143.730 118.845 1.00 115.49 ? 324 ILE R N   1 
ATOM 6222 C CA  . ILE E 5 388 ? 163.697 143.770 120.300 1.00 118.67 ? 324 ILE R CA  1 
ATOM 6223 C C   . ILE E 5 388 ? 162.915 142.621 120.923 1.00 112.04 ? 324 ILE R C   1 
ATOM 6224 O O   . ILE E 5 388 ? 163.411 141.911 121.809 1.00 110.99 ? 324 ILE R O   1 
ATOM 6225 C CB  . ILE E 5 388 ? 163.223 145.127 120.843 1.00 115.07 ? 324 ILE R CB  1 
ATOM 6226 C CG1 . ILE E 5 388 ? 163.958 146.267 120.145 1.00 112.94 ? 324 ILE R CG1 1 
ATOM 6227 C CG2 . ILE E 5 388 ? 163.424 145.197 122.347 1.00 109.71 ? 324 ILE R CG2 1 
ATOM 6228 C CD1 . ILE E 5 388 ? 163.450 147.629 120.527 1.00 114.00 ? 324 ILE R CD1 1 
ATOM 6229 N N   . TYR E 5 389 ? 161.675 142.420 120.465 1.00 109.39 ? 325 TYR R N   1 
ATOM 6230 C CA  . TYR E 5 389 ? 160.881 141.326 121.012 1.00 111.90 ? 325 TYR R CA  1 
ATOM 6231 C C   . TYR E 5 389 ? 161.554 139.985 120.766 1.00 115.35 ? 325 TYR R C   1 
ATOM 6232 O O   . TYR E 5 389 ? 161.599 139.137 121.659 1.00 122.15 ? 325 TYR R O   1 
ATOM 6233 C CB  . TYR E 5 389 ? 159.477 141.316 120.414 1.00 106.10 ? 325 TYR R CB  1 
ATOM 6234 C CG  . TYR E 5 389 ? 158.749 140.038 120.751 1.00 112.03 ? 325 TYR R CG  1 
ATOM 6235 C CD1 . TYR E 5 389 ? 158.275 139.809 122.032 1.00 117.71 ? 325 TYR R CD1 1 
ATOM 6236 C CD2 . TYR E 5 389 ? 158.558 139.051 119.796 1.00 114.15 ? 325 TYR R CD2 1 
ATOM 6237 C CE1 . TYR E 5 389 ? 157.617 138.638 122.354 1.00 118.95 ? 325 TYR R CE1 1 
ATOM 6238 C CE2 . TYR E 5 389 ? 157.899 137.876 120.107 1.00 118.60 ? 325 TYR R CE2 1 
ATOM 6239 C CZ  . TYR E 5 389 ? 157.433 137.672 121.388 1.00 121.19 ? 325 TYR R CZ  1 
ATOM 6240 O OH  . TYR E 5 389 ? 156.777 136.502 121.698 1.00 120.15 ? 325 TYR R OH  1 
ATOM 6241 N N   . ALA E 5 390 ? 162.067 139.771 119.555 1.00 134.56 ? 326 ALA R N   1 
ATOM 6242 C CA  . ALA E 5 390 ? 162.796 138.541 119.271 1.00 139.80 ? 326 ALA R CA  1 
ATOM 6243 C C   . ALA E 5 390 ? 164.018 138.403 120.168 1.00 139.02 ? 326 ALA R C   1 
ATOM 6244 O O   . ALA E 5 390 ? 164.366 137.292 120.583 1.00 145.75 ? 326 ALA R O   1 
ATOM 6245 C CB  . ALA E 5 390 ? 163.204 138.494 117.801 1.00 142.95 ? 326 ALA R CB  1 
ATOM 6246 N N   . SER E 5 391 ? 164.685 139.519 120.477 1.00 118.96 ? 327 SER R N   1 
ATOM 6247 C CA  . SER E 5 391 ? 165.831 139.459 121.374 1.00 119.68 ? 327 SER R CA  1 
ATOM 6248 C C   . SER E 5 391 ? 165.408 139.034 122.770 1.00 120.64 ? 327 SER R C   1 
ATOM 6249 O O   . SER E 5 391 ? 166.146 138.320 123.457 1.00 119.25 ? 327 SER R O   1 
ATOM 6250 C CB  . SER E 5 391 ? 166.538 140.809 121.417 1.00 122.25 ? 327 SER R CB  1 
ATOM 6251 O OG  . SER E 5 391 ? 167.206 141.074 120.196 1.00 124.53 ? 327 SER R OG  1 
ATOM 6252 N N   . PHE E 5 392 ? 164.229 139.462 123.209 1.00 122.09 ? 328 PHE R N   1 
ATOM 6253 C CA  . PHE E 5 392 ? 163.807 139.131 124.566 1.00 123.14 ? 328 PHE R CA  1 
ATOM 6254 C C   . PHE E 5 392 ? 163.127 137.766 124.669 1.00 119.11 ? 328 PHE R C   1 
ATOM 6255 O O   . PHE E 5 392 ? 163.340 137.043 125.648 1.00 116.91 ? 328 PHE R O   1 
ATOM 6256 C CB  . PHE E 5 392 ? 162.883 140.224 125.108 1.00 123.24 ? 328 PHE R CB  1 
ATOM 6257 C CG  . PHE E 5 392 ? 163.617 141.388 125.699 1.00 124.94 ? 328 PHE R CG  1 
ATOM 6258 C CD1 . PHE E 5 392 ? 163.975 142.467 124.914 1.00 129.79 ? 328 PHE R CD1 1 
ATOM 6259 C CD2 . PHE E 5 392 ? 163.954 141.401 127.043 1.00 125.59 ? 328 PHE R CD2 1 
ATOM 6260 C CE1 . PHE E 5 392 ? 164.653 143.538 125.456 1.00 134.30 ? 328 PHE R CE1 1 
ATOM 6261 C CE2 . PHE E 5 392 ? 164.631 142.469 127.591 1.00 126.20 ? 328 PHE R CE2 1 
ATOM 6262 C CZ  . PHE E 5 392 ? 164.981 143.539 126.796 1.00 127.73 ? 328 PHE R CZ  1 
ATOM 6263 N N   . SER E 5 393 ? 162.321 137.391 123.681 1.00 123.88 ? 329 SER R N   1 
ATOM 6264 C CA  . SER E 5 393 ? 161.479 136.202 123.750 1.00 126.42 ? 329 SER R CA  1 
ATOM 6265 C C   . SER E 5 393 ? 162.242 134.993 123.213 1.00 130.23 ? 329 SER R C   1 
ATOM 6266 O O   . SER E 5 393 ? 162.599 134.946 122.024 1.00 131.19 ? 329 SER R O   1 
ATOM 6267 C CB  . SER E 5 393 ? 160.184 136.416 122.966 1.00 124.81 ? 329 SER R CB  1 
ATOM 6268 O OG  . SER E 5 393 ? 159.429 135.222 122.900 1.00 122.00 ? 329 SER R OG  1 
ATOM 6269 N N   . SER E 5 394 ? 162.489 134.014 124.088 1.00 167.16 ? 330 SER R N   1 
ATOM 6270 C CA  . SER E 5 394 ? 163.252 132.831 123.693 1.00 167.77 ? 330 SER R CA  1 
ATOM 6271 C C   . SER E 5 394 ? 162.505 131.960 122.689 1.00 167.02 ? 330 SER R C   1 
ATOM 6272 O O   . SER E 5 394 ? 163.136 131.379 121.799 1.00 166.97 ? 330 SER R O   1 
ATOM 6273 C CB  . SER E 5 394 ? 163.619 132.006 124.923 1.00 166.15 ? 330 SER R CB  1 
ATOM 6274 O OG  . SER E 5 394 ? 162.461 131.623 125.646 1.00 167.10 ? 330 SER R OG  1 
ATOM 6275 N N   . SER E 5 395 ? 161.178 131.858 122.802 1.00 168.54 ? 331 SER R N   1 
ATOM 6276 C CA  . SER E 5 395 ? 160.427 130.981 121.907 1.00 168.97 ? 331 SER R CA  1 
ATOM 6277 C C   . SER E 5 395 ? 160.509 131.463 120.462 1.00 168.27 ? 331 SER R C   1 
ATOM 6278 O O   . SER E 5 395 ? 160.841 130.692 119.549 1.00 168.18 ? 331 SER R O   1 
ATOM 6279 C CB  . SER E 5 395 ? 158.971 130.896 122.364 1.00 169.11 ? 331 SER R CB  1 
ATOM 6280 O OG  . SER E 5 395 ? 158.879 130.377 123.679 1.00 167.47 ? 331 SER R OG  1 
ATOM 6281 N N   . VAL E 5 396 ? 160.224 132.746 120.239 1.00 153.89 ? 332 VAL R N   1 
ATOM 6282 C CA  . VAL E 5 396 ? 160.249 133.290 118.886 1.00 153.73 ? 332 VAL R CA  1 
ATOM 6283 C C   . VAL E 5 396 ? 161.671 133.305 118.346 1.00 154.79 ? 332 VAL R C   1 
ATOM 6284 O O   . VAL E 5 396 ? 161.904 133.020 117.162 1.00 153.45 ? 332 VAL R O   1 
ATOM 6285 C CB  . VAL E 5 396 ? 159.609 134.689 118.872 1.00 153.82 ? 332 VAL R CB  1 
ATOM 6286 C CG1 . VAL E 5 396 ? 159.938 135.422 117.584 1.00 155.88 ? 332 VAL R CG1 1 
ATOM 6287 C CG2 . VAL E 5 396 ? 158.110 134.569 119.050 1.00 154.93 ? 332 VAL R CG2 1 
ATOM 6288 N N   . SER E 5 397 ? 162.647 133.629 119.206 1.00 169.05 ? 333 SER R N   1 
ATOM 6289 C CA  . SER E 5 397 ? 164.039 133.578 118.772 1.00 171.07 ? 333 SER R CA  1 
ATOM 6290 C C   . SER E 5 397 ? 164.411 132.185 118.282 1.00 170.41 ? 333 SER R C   1 
ATOM 6291 O O   . SER E 5 397 ? 165.049 132.037 117.233 1.00 169.53 ? 333 SER R O   1 
ATOM 6292 C CB  . SER E 5 397 ? 164.953 134.007 119.918 1.00 169.83 ? 333 SER R CB  1 
ATOM 6293 O OG  . SER E 5 397 ? 166.316 133.975 119.530 1.00 169.09 ? 333 SER R OG  1 
ATOM 6294 N N   . SER E 5 398 ? 164.007 131.149 119.023 1.00 177.69 ? 334 SER R N   1 
ATOM 6295 C CA  . SER E 5 398 ? 164.289 129.787 118.592 1.00 177.24 ? 334 SER R CA  1 
ATOM 6296 C C   . SER E 5 398 ? 163.596 129.478 117.279 1.00 176.80 ? 334 SER R C   1 
ATOM 6297 O O   . SER E 5 398 ? 164.160 128.798 116.417 1.00 177.39 ? 334 SER R O   1 
ATOM 6298 C CB  . SER E 5 398 ? 163.854 128.790 119.665 1.00 177.59 ? 334 SER R CB  1 
ATOM 6299 O OG  . SER E 5 398 ? 164.563 128.996 120.873 1.00 179.24 ? 334 SER R OG  1 
ATOM 6300 N N   . GLU E 5 399 ? 162.362 129.950 117.116 1.00 171.14 ? 335 GLU R N   1 
ATOM 6301 C CA  . GLU E 5 399 ? 161.638 129.672 115.879 1.00 172.61 ? 335 GLU R CA  1 
ATOM 6302 C C   . GLU E 5 399 ? 162.267 130.369 114.678 1.00 172.01 ? 335 GLU R C   1 
ATOM 6303 O O   . GLU E 5 399 ? 162.180 129.859 113.554 1.00 172.07 ? 335 GLU R O   1 
ATOM 6304 C CB  . GLU E 5 399 ? 160.176 130.087 116.018 1.00 171.71 ? 335 GLU R CB  1 
ATOM 6305 N N   . LEU E 5 400 ? 162.906 131.518 114.888 1.00 158.71 ? 336 LEU R N   1 
ATOM 6306 C CA  . LEU E 5 400 ? 163.447 132.305 113.787 1.00 158.79 ? 336 LEU R CA  1 
ATOM 6307 C C   . LEU E 5 400 ? 164.807 131.814 113.310 1.00 159.09 ? 336 LEU R C   1 
ATOM 6308 O O   . LEU E 5 400 ? 165.377 132.416 112.396 1.00 157.50 ? 336 LEU R O   1 
ATOM 6309 C CB  . LEU E 5 400 ? 163.541 133.780 114.190 1.00 157.06 ? 336 LEU R CB  1 
ATOM 6310 N N   . ARG E 5 401 ? 165.337 130.749 113.891 1.00 157.46 ? 337 ARG R N   1 
ATOM 6311 C CA  . ARG E 5 401 ? 166.597 130.213 113.435 1.00 157.58 ? 337 ARG R CA  1 
ATOM 6312 C C   . ARG E 5 401 ? 166.404 128.834 112.849 1.00 156.72 ? 337 ARG R C   1 
ATOM 6313 O O   . ARG E 5 401 ? 166.628 128.629 111.666 1.00 153.96 ? 337 ARG R O   1 
ATOM 6314 C CB  . ARG E 5 401 ? 167.604 130.171 114.582 1.00 157.78 ? 337 ARG R CB  1 
ATOM 6315 N N   . ALA E 5 436 ? 156.622 142.631 145.329 1.00 94.95  ? 500 ALA R N   1 
ATOM 6316 C CA  . ALA E 5 436 ? 157.031 141.236 145.259 1.00 99.13  ? 500 ALA R CA  1 
ATOM 6317 C C   . ALA E 5 436 ? 158.476 141.052 145.712 1.00 95.59  ? 500 ALA R C   1 
ATOM 6318 O O   . ALA E 5 436 ? 158.767 140.173 146.518 1.00 110.48 ? 500 ALA R O   1 
ATOM 6319 C CB  . ALA E 5 436 ? 156.849 140.706 143.846 1.00 100.10 ? 500 ALA R CB  1 
ATOM 6320 N N   . ARG E 5 437 ? 159.372 141.896 145.193 1.00 80.42  ? 501 ARG R N   1 
ATOM 6321 C CA  . ARG E 5 437 ? 160.802 141.726 145.445 1.00 90.89  ? 501 ARG R CA  1 
ATOM 6322 C C   . ARG E 5 437 ? 161.135 141.874 146.925 1.00 100.62 ? 501 ARG R C   1 
ATOM 6323 O O   . ARG E 5 437 ? 161.844 141.039 147.495 1.00 116.22 ? 501 ARG R O   1 
ATOM 6324 C CB  . ARG E 5 437 ? 161.603 142.732 144.619 1.00 97.38  ? 501 ARG R CB  1 
ATOM 6325 C CG  . ARG E 5 437 ? 163.104 142.649 144.817 1.00 100.09 ? 501 ARG R CG  1 
ATOM 6326 C CD  . ARG E 5 437 ? 163.810 143.753 144.049 1.00 106.17 ? 501 ARG R CD  1 
ATOM 6327 N NE  . ARG E 5 437 ? 163.490 143.717 142.627 1.00 106.16 ? 501 ARG R NE  1 
ATOM 6328 C CZ  . ARG E 5 437 ? 163.807 144.671 141.763 1.00 106.56 ? 501 ARG R CZ  1 
ATOM 6329 N NH1 . ARG E 5 437 ? 164.455 145.761 142.143 1.00 106.69 ? 501 ARG R NH1 1 
ATOM 6330 N NH2 . ARG E 5 437 ? 163.463 144.531 140.486 1.00 102.02 ? 501 ARG R NH2 1 
ATOM 6331 N N   . ARG E 5 438 ? 160.660 142.949 147.558 1.00 115.91 ? 502 ARG R N   1 
ATOM 6332 C CA  . ARG E 5 438 ? 160.987 143.175 148.965 1.00 122.68 ? 502 ARG R CA  1 
ATOM 6333 C C   . ARG E 5 438 ? 160.381 142.098 149.858 1.00 126.74 ? 502 ARG R C   1 
ATOM 6334 O O   . ARG E 5 438 ? 161.028 141.625 150.802 1.00 132.33 ? 502 ARG R O   1 
ATOM 6335 C CB  . ARG E 5 438 ? 160.519 144.564 149.396 1.00 124.55 ? 502 ARG R CB  1 
ATOM 6336 C CG  . ARG E 5 438 ? 161.477 145.679 149.012 1.00 127.98 ? 502 ARG R CG  1 
ATOM 6337 C CD  . ARG E 5 438 ? 160.843 147.047 149.191 1.00 130.47 ? 502 ARG R CD  1 
ATOM 6338 N NE  . ARG E 5 438 ? 161.643 148.099 148.576 1.00 131.91 ? 502 ARG R NE  1 
ATOM 6339 C CZ  . ARG E 5 438 ? 161.240 149.353 148.427 1.00 131.78 ? 502 ARG R CZ  1 
ATOM 6340 N NH1 . ARG E 5 438 ? 160.045 149.748 148.836 1.00 131.49 ? 502 ARG R NH1 1 
ATOM 6341 N NH2 . ARG E 5 438 ? 162.054 150.233 147.850 1.00 128.84 ? 502 ARG R NH2 1 
ATOM 6342 N N   . GLN E 5 439 ? 159.140 141.701 149.578 1.00 146.41 ? 503 GLN R N   1 
ATOM 6343 C CA  . GLN E 5 439 ? 158.524 140.619 150.337 1.00 149.07 ? 503 GLN R CA  1 
ATOM 6344 C C   . GLN E 5 439 ? 159.271 139.306 150.124 1.00 151.04 ? 503 GLN R C   1 
ATOM 6345 O O   . GLN E 5 439 ? 159.426 138.511 151.058 1.00 156.86 ? 503 GLN R O   1 
ATOM 6346 C CB  . GLN E 5 439 ? 157.055 140.483 149.942 1.00 151.58 ? 503 GLN R CB  1 
ATOM 6347 C CG  . GLN E 5 439 ? 156.211 141.718 150.213 1.00 158.68 ? 503 GLN R CG  1 
ATOM 6348 C CD  . GLN E 5 439 ? 155.808 141.846 151.669 1.00 162.44 ? 503 GLN R CD  1 
ATOM 6349 O OE1 . GLN E 5 439 ? 155.414 140.868 152.304 1.00 164.62 ? 503 GLN R OE1 1 
ATOM 6350 N NE2 . GLN E 5 439 ? 155.904 143.057 152.206 1.00 161.31 ? 503 GLN R NE2 1 
ATOM 6351 N N   . LEU E 5 440 ? 159.744 139.064 148.899 1.00 153.19 ? 504 LEU R N   1 
ATOM 6352 C CA  . LEU E 5 440 ? 160.560 137.883 148.636 1.00 155.24 ? 504 LEU R CA  1 
ATOM 6353 C C   . LEU E 5 440 ? 161.876 137.934 149.404 1.00 158.04 ? 504 LEU R C   1 
ATOM 6354 O O   . LEU E 5 440 ? 162.363 136.905 149.881 1.00 164.96 ? 504 LEU R O   1 
ATOM 6355 C CB  . LEU E 5 440 ? 160.822 137.747 147.136 1.00 157.95 ? 504 LEU R CB  1 
ATOM 6356 C CG  . LEU E 5 440 ? 159.702 137.129 146.296 1.00 159.83 ? 504 LEU R CG  1 
ATOM 6357 C CD1 . LEU E 5 440 ? 160.012 137.243 144.811 1.00 158.79 ? 504 LEU R CD1 1 
ATOM 6358 C CD2 . LEU E 5 440 ? 159.478 135.677 146.688 1.00 158.51 ? 504 LEU R CD2 1 
ATOM 6359 N N   . ALA E 5 441 ? 162.479 139.119 149.512 1.00 174.92 ? 505 ALA R N   1 
ATOM 6360 C CA  . ALA E 5 441 ? 163.707 139.260 150.289 1.00 177.43 ? 505 ALA R CA  1 
ATOM 6361 C C   . ALA E 5 441 ? 163.458 138.979 151.766 1.00 181.10 ? 505 ALA R C   1 
ATOM 6362 O O   . ALA E 5 441 ? 164.285 138.348 152.437 1.00 183.59 ? 505 ALA R O   1 
ATOM 6363 C CB  . ALA E 5 441 ? 164.289 140.659 150.099 1.00 178.09 ? 505 ALA R CB  1 
ATOM 6364 N N   . ASP E 5 442 ? 162.327 139.454 152.291 1.00 199.38 ? 506 ASP R N   1 
ATOM 6365 C CA  . ASP E 5 442 ? 161.958 139.132 153.668 1.00 200.19 ? 506 ASP R CA  1 
ATOM 6366 C C   . ASP E 5 442 ? 161.760 137.631 153.845 1.00 201.70 ? 506 ASP R C   1 
ATOM 6367 O O   . ASP E 5 442 ? 162.190 137.050 154.851 1.00 203.28 ? 506 ASP R O   1 
ATOM 6368 C CB  . ASP E 5 442 ? 160.690 139.888 154.062 1.00 198.63 ? 506 ASP R CB  1 
ATOM 6369 C CG  . ASP E 5 442 ? 160.893 141.385 154.092 1.00 200.64 ? 506 ASP R CG  1 
ATOM 6370 O OD1 . ASP E 5 442 ? 162.051 141.829 153.943 1.00 201.53 ? 506 ASP R OD1 1 
ATOM 6371 O OD2 . ASP E 5 442 ? 159.898 142.119 154.263 1.00 201.88 ? 506 ASP R OD2 1 
ATOM 6372 N N   . LEU E 5 443 ? 161.110 136.988 152.872 1.00 211.46 ? 507 LEU R N   1 
ATOM 6373 C CA  . LEU E 5 443 ? 160.942 135.540 152.920 1.00 210.86 ? 507 LEU R CA  1 
ATOM 6374 C C   . LEU E 5 443 ? 162.288 134.831 152.922 1.00 211.41 ? 507 LEU R C   1 
ATOM 6375 O O   . LEU E 5 443 ? 162.490 133.871 153.673 1.00 214.61 ? 507 LEU R O   1 
ATOM 6376 C CB  . LEU E 5 443 ? 160.096 135.070 151.739 1.00 210.62 ? 507 LEU R CB  1 
ATOM 6377 C CG  . LEU E 5 443 ? 158.591 135.256 151.899 1.00 210.24 ? 507 LEU R CG  1 
ATOM 6378 C CD1 . LEU E 5 443 ? 157.849 134.663 150.717 1.00 211.57 ? 507 LEU R CD1 1 
ATOM 6379 C CD2 . LEU E 5 443 ? 158.151 134.609 153.189 1.00 212.82 ? 507 LEU R CD2 1 
ATOM 6380 N N   . GLU E 5 444 ? 163.218 135.291 152.084 1.00 211.53 ? 508 GLU R N   1 
ATOM 6381 C CA  . GLU E 5 444 ? 164.545 134.688 152.039 1.00 212.25 ? 508 GLU R CA  1 
ATOM 6382 C C   . GLU E 5 444 ? 165.263 134.843 153.370 1.00 213.82 ? 508 GLU R C   1 
ATOM 6383 O O   . GLU E 5 444 ? 165.905 133.903 153.848 1.00 214.56 ? 508 GLU R O   1 
ATOM 6384 C CB  . GLU E 5 444 ? 165.376 135.312 150.916 1.00 212.03 ? 508 GLU R CB  1 
ATOM 6385 C CG  . GLU E 5 444 ? 164.979 134.885 149.515 1.00 211.87 ? 508 GLU R CG  1 
ATOM 6386 C CD  . GLU E 5 444 ? 165.981 135.331 148.465 1.00 212.41 ? 508 GLU R CD  1 
ATOM 6387 O OE1 . GLU E 5 444 ? 166.988 135.974 148.830 1.00 212.36 ? 508 GLU R OE1 1 
ATOM 6388 O OE2 . GLU E 5 444 ? 165.763 135.034 147.272 1.00 213.11 ? 508 GLU R OE2 1 
ATOM 6389 N N   . ASP E 5 445 ? 165.173 136.027 153.980 1.00 228.95 ? 509 ASP R N   1 
ATOM 6390 C CA  . ASP E 5 445 ? 165.830 136.240 155.267 1.00 229.44 ? 509 ASP R CA  1 
ATOM 6391 C C   . ASP E 5 445 ? 165.241 135.337 156.342 1.00 231.11 ? 509 ASP R C   1 
ATOM 6392 O O   . ASP E 5 445 ? 165.978 134.743 157.140 1.00 231.26 ? 509 ASP R O   1 
ATOM 6393 C CB  . ASP E 5 445 ? 165.720 137.706 155.680 1.00 228.77 ? 509 ASP R CB  1 
ATOM 6394 C CG  . ASP E 5 445 ? 166.628 138.604 154.872 1.00 229.84 ? 509 ASP R CG  1 
ATOM 6395 O OD1 . ASP E 5 445 ? 167.399 138.077 154.042 1.00 229.47 ? 509 ASP R OD1 1 
ATOM 6396 O OD2 . ASP E 5 445 ? 166.572 139.836 155.068 1.00 231.59 ? 509 ASP R OD2 1 
ATOM 6397 N N   . ASN E 5 446 ? 163.914 135.204 156.367 1.00 267.57 ? 510 ASN R N   1 
ATOM 6398 C CA  . ASN E 5 446 ? 163.287 134.375 157.389 1.00 268.67 ? 510 ASN R CA  1 
ATOM 6399 C C   . ASN E 5 446 ? 163.577 132.897 157.163 1.00 268.30 ? 510 ASN R C   1 
ATOM 6400 O O   . ASN E 5 446 ? 163.747 132.142 158.127 1.00 269.63 ? 510 ASN R O   1 
ATOM 6401 C CB  . ASN E 5 446 ? 161.784 134.641 157.421 1.00 268.94 ? 510 ASN R CB  1 
ATOM 6402 C CG  . ASN E 5 446 ? 161.457 136.056 157.849 1.00 269.74 ? 510 ASN R CG  1 
ATOM 6403 O OD1 . ASN E 5 446 ? 162.195 136.669 158.621 1.00 269.39 ? 510 ASN R OD1 1 
ATOM 6404 N ND2 . ASN E 5 446 ? 160.351 136.586 157.346 1.00 270.21 ? 510 ASN R ND2 1 
ATOM 6405 N N   . TRP E 5 447 ? 163.666 132.470 155.903 1.00 249.43 ? 511 TRP R N   1 
ATOM 6406 C CA  . TRP E 5 447 ? 163.998 131.079 155.617 1.00 249.26 ? 511 TRP R CA  1 
ATOM 6407 C C   . TRP E 5 447 ? 165.459 130.779 155.928 1.00 250.08 ? 511 TRP R C   1 
ATOM 6408 O O   . TRP E 5 447 ? 165.783 129.683 156.396 1.00 251.82 ? 511 TRP R O   1 
ATOM 6409 C CB  . TRP E 5 447 ? 163.660 130.758 154.163 1.00 249.95 ? 511 TRP R CB  1 
ATOM 6410 C CG  . TRP E 5 447 ? 162.194 130.866 153.907 1.00 250.02 ? 511 TRP R CG  1 
ATOM 6411 C CD1 . TRP E 5 447 ? 161.199 130.724 154.825 1.00 248.34 ? 511 TRP R CD1 1 
ATOM 6412 C CD2 . TRP E 5 447 ? 161.551 131.173 152.662 1.00 250.17 ? 511 TRP R CD2 1 
ATOM 6413 N NE1 . TRP E 5 447 ? 159.977 130.905 154.230 1.00 247.99 ? 511 TRP R NE1 1 
ATOM 6414 C CE2 . TRP E 5 447 ? 160.163 131.182 152.902 1.00 249.32 ? 511 TRP R CE2 1 
ATOM 6415 C CE3 . TRP E 5 447 ? 162.013 131.429 151.368 1.00 248.93 ? 511 TRP R CE3 1 
ATOM 6416 C CZ2 . TRP E 5 447 ? 159.232 131.440 151.896 1.00 248.95 ? 511 TRP R CZ2 1 
ATOM 6417 C CZ3 . TRP E 5 447 ? 161.085 131.686 150.372 1.00 247.83 ? 511 TRP R CZ3 1 
ATOM 6418 C CH2 . TRP E 5 447 ? 159.713 131.687 150.641 1.00 248.11 ? 511 TRP R CH2 1 
ATOM 6419 N N   . GLU E 5 448 ? 166.354 131.739 155.685 1.00 261.16 ? 512 GLU R N   1 
ATOM 6420 C CA  . GLU E 5 448 ? 167.744 131.570 156.098 1.00 262.02 ? 512 GLU R CA  1 
ATOM 6421 C C   . GLU E 5 448 ? 167.859 131.499 157.615 1.00 263.44 ? 512 GLU R C   1 
ATOM 6422 O O   . GLU E 5 448 ? 168.660 130.723 158.149 1.00 263.63 ? 512 GLU R O   1 
ATOM 6423 C CB  . GLU E 5 448 ? 168.606 132.705 155.546 1.00 261.07 ? 512 GLU R CB  1 
ATOM 6424 C CG  . GLU E 5 448 ? 168.800 132.672 154.036 1.00 261.39 ? 512 GLU R CG  1 
ATOM 6425 C CD  . GLU E 5 448 ? 169.439 131.385 153.554 1.00 261.92 ? 512 GLU R CD  1 
ATOM 6426 O OE1 . GLU E 5 448 ? 170.409 130.922 154.192 1.00 262.29 ? 512 GLU R OE1 1 
ATOM 6427 O OE2 . GLU E 5 448 ? 168.962 130.830 152.541 1.00 261.87 ? 512 GLU R OE2 1 
ATOM 6428 N N   . THR E 5 449 ? 167.067 132.307 158.328 1.00 279.78 ? 513 THR R N   1 
ATOM 6429 C CA  . THR E 5 449 ? 167.038 132.220 159.786 1.00 280.09 ? 513 THR R CA  1 
ATOM 6430 C C   . THR E 5 449 ? 166.526 130.859 160.247 1.00 281.23 ? 513 THR R C   1 
ATOM 6431 O O   . THR E 5 449 ? 167.082 130.259 161.175 1.00 281.79 ? 513 THR R O   1 
ATOM 6432 C CB  . THR E 5 449 ? 166.174 133.344 160.360 1.00 279.66 ? 513 THR R CB  1 
ATOM 6433 O OG1 . THR E 5 449 ? 166.688 134.609 159.927 1.00 278.95 ? 513 THR R OG1 1 
ATOM 6434 C CG2 . THR E 5 449 ? 166.172 133.302 161.880 1.00 279.79 ? 513 THR R CG2 1 
ATOM 6435 N N   . LEU E 5 450 ? 165.470 130.353 159.603 1.00 292.82 ? 514 LEU R N   1 
ATOM 6436 C CA  . LEU E 5 450 ? 164.955 129.028 159.936 1.00 292.15 ? 514 LEU R CA  1 
ATOM 6437 C C   . LEU E 5 450 ? 166.001 127.948 159.685 1.00 292.33 ? 514 LEU R C   1 
ATOM 6438 O O   . LEU E 5 450 ? 166.161 127.029 160.494 1.00 293.25 ? 514 LEU R O   1 
ATOM 6439 C CB  . LEU E 5 450 ? 163.685 128.736 159.134 1.00 291.29 ? 514 LEU R CB  1 
ATOM 6440 C CG  . LEU E 5 450 ? 162.421 129.537 159.453 1.00 291.69 ? 514 LEU R CG  1 
ATOM 6441 C CD1 . LEU E 5 450 ? 161.288 129.171 158.505 1.00 291.08 ? 514 LEU R CD1 1 
ATOM 6442 C CD2 . LEU E 5 450 ? 162.003 129.313 160.891 1.00 293.11 ? 514 LEU R CD2 1 
ATOM 6443 N N   . ASN E 5 451 ? 166.721 128.039 158.565 1.00 292.94 ? 515 ASN R N   1 
ATOM 6444 C CA  . ASN E 5 451 ? 167.743 127.043 158.257 1.00 293.12 ? 515 ASN R CA  1 
ATOM 6445 C C   . ASN E 5 451 ? 168.900 127.099 159.250 1.00 293.59 ? 515 ASN R C   1 
ATOM 6446 O O   . ASN E 5 451 ? 169.404 126.056 159.684 1.00 294.40 ? 515 ASN R O   1 
ATOM 6447 C CB  . ASN E 5 451 ? 168.247 127.236 156.827 1.00 292.90 ? 515 ASN R CB  1 
ATOM 6448 C CG  . ASN E 5 451 ? 167.149 127.062 155.793 1.00 292.90 ? 515 ASN R CG  1 
ATOM 6449 O OD1 . ASN E 5 451 ? 166.166 126.359 156.027 1.00 292.66 ? 515 ASN R OD1 1 
ATOM 6450 N ND2 . ASN E 5 451 ? 167.313 127.703 154.641 1.00 292.95 ? 515 ASN R ND2 1 
ATOM 6451 N N   . ASP E 5 452 ? 169.345 128.306 159.614 1.00 298.94 ? 516 ASP R N   1 
ATOM 6452 C CA  . ASP E 5 452 ? 170.412 128.428 160.603 1.00 299.28 ? 516 ASP R CA  1 
ATOM 6453 C C   . ASP E 5 452 ? 169.970 127.890 161.956 1.00 300.20 ? 516 ASP R C   1 
ATOM 6454 O O   . ASP E 5 452 ? 170.747 127.233 162.659 1.00 300.28 ? 516 ASP R O   1 
ATOM 6455 C CB  . ASP E 5 452 ? 170.858 129.883 160.726 1.00 298.75 ? 516 ASP R CB  1 
ATOM 6456 C CG  . ASP E 5 452 ? 171.663 130.342 159.536 1.00 298.95 ? 516 ASP R CG  1 
ATOM 6457 O OD1 . ASP E 5 452 ? 171.967 129.499 158.666 1.00 298.81 ? 516 ASP R OD1 1 
ATOM 6458 O OD2 . ASP E 5 452 ? 171.991 131.545 159.469 1.00 299.48 ? 516 ASP R OD2 1 
ATOM 6459 N N   . ASN E 5 453 ? 168.717 128.150 162.335 1.00 323.15 ? 517 ASN R N   1 
ATOM 6460 C CA  . ASN E 5 453 ? 168.200 127.581 163.572 1.00 323.67 ? 517 ASN R CA  1 
ATOM 6461 C C   . ASN E 5 453 ? 168.114 126.061 163.497 1.00 323.71 ? 517 ASN R C   1 
ATOM 6462 O O   . ASN E 5 453 ? 168.323 125.384 164.506 1.00 323.97 ? 517 ASN R O   1 
ATOM 6463 C CB  . ASN E 5 453 ? 166.833 128.180 163.894 1.00 324.12 ? 517 ASN R CB  1 
ATOM 6464 C CG  . ASN E 5 453 ? 166.913 129.637 164.303 1.00 324.09 ? 517 ASN R CG  1 
ATOM 6465 O OD1 . ASN E 5 453 ? 167.830 130.048 165.014 1.00 323.40 ? 517 ASN R OD1 1 
ATOM 6466 N ND2 . ASN E 5 453 ? 165.944 130.428 163.856 1.00 324.54 ? 517 ASN R ND2 1 
ATOM 6467 N N   . LEU E 5 454 ? 167.798 125.508 162.322 1.00 311.16 ? 518 LEU R N   1 
ATOM 6468 C CA  . LEU E 5 454 ? 167.824 124.056 162.158 1.00 310.21 ? 518 LEU R CA  1 
ATOM 6469 C C   . LEU E 5 454 ? 169.235 123.513 162.341 1.00 310.48 ? 518 LEU R C   1 
ATOM 6470 O O   . LEU E 5 454 ? 169.432 122.455 162.957 1.00 310.80 ? 518 LEU R O   1 
ATOM 6471 C CB  . LEU E 5 454 ? 167.266 123.673 160.787 1.00 309.79 ? 518 LEU R CB  1 
ATOM 6472 C CG  . LEU E 5 454 ? 165.742 123.671 160.622 1.00 309.66 ? 518 LEU R CG  1 
ATOM 6473 C CD1 . LEU E 5 454 ? 165.349 123.609 159.156 1.00 309.69 ? 518 LEU R CD1 1 
ATOM 6474 C CD2 . LEU E 5 454 ? 165.123 122.508 161.380 1.00 309.13 ? 518 LEU R CD2 1 
ATOM 6475 N N   . LYS E 5 455 ? 170.228 124.224 161.804 1.00 310.87 ? 519 LYS R N   1 
ATOM 6476 C CA  . LYS E 5 455 ? 171.621 123.845 162.025 1.00 310.86 ? 519 LYS R CA  1 
ATOM 6477 C C   . LYS E 5 455 ? 171.960 123.855 163.510 1.00 311.12 ? 519 LYS R C   1 
ATOM 6478 O O   . LYS E 5 455 ? 172.666 122.957 164.014 1.00 310.86 ? 519 LYS R O   1 
ATOM 6479 C CB  . LYS E 5 455 ? 172.554 124.788 161.266 1.00 310.33 ? 519 LYS R CB  1 
ATOM 6480 C CG  . LYS E 5 455 ? 172.323 124.848 159.768 1.00 310.09 ? 519 LYS R CG  1 
ATOM 6481 C CD  . LYS E 5 455 ? 173.216 125.899 159.128 1.00 309.78 ? 519 LYS R CD  1 
ATOM 6482 C CE  . LYS E 5 455 ? 172.913 126.064 157.649 1.00 310.09 ? 519 LYS R CE  1 
ATOM 6483 N NZ  . LYS E 5 455 ? 173.843 127.037 157.012 1.00 309.73 ? 519 LYS R NZ  1 
ATOM 6484 N N   . VAL E 5 456 ? 171.462 124.860 164.233 1.00 316.48 ? 520 VAL R N   1 
ATOM 6485 C CA  . VAL E 5 456 ? 171.697 124.925 165.673 1.00 316.11 ? 520 VAL R CA  1 
ATOM 6486 C C   . VAL E 5 456 ? 171.019 123.757 166.385 1.00 316.07 ? 520 VAL R C   1 
ATOM 6487 O O   . VAL E 5 456 ? 171.589 123.156 167.307 1.00 315.91 ? 520 VAL R O   1 
ATOM 6488 C CB  . VAL E 5 456 ? 171.225 126.282 166.225 1.00 315.98 ? 520 VAL R CB  1 
ATOM 6489 C CG1 . VAL E 5 456 ? 171.404 126.339 167.732 1.00 315.89 ? 520 VAL R CG1 1 
ATOM 6490 C CG2 . VAL E 5 456 ? 171.987 127.412 165.558 1.00 315.97 ? 520 VAL R CG2 1 
ATOM 6491 N N   . ILE E 5 457 ? 169.797 123.419 165.971 1.00 325.20 ? 521 ILE R N   1 
ATOM 6492 C CA  . ILE E 5 457 ? 169.048 122.343 166.617 1.00 325.43 ? 521 ILE R CA  1 
ATOM 6493 C C   . ILE E 5 457 ? 169.765 121.012 166.442 1.00 325.53 ? 521 ILE R C   1 
ATOM 6494 O O   . ILE E 5 457 ? 169.984 120.272 167.408 1.00 325.76 ? 521 ILE R O   1 
ATOM 6495 C CB  . ILE E 5 457 ? 167.617 122.272 166.056 1.00 325.35 ? 521 ILE R CB  1 
ATOM 6496 C CG1 . ILE E 5 457 ? 166.802 123.491 166.491 1.00 325.65 ? 521 ILE R CG1 1 
ATOM 6497 C CG2 . ILE E 5 457 ? 166.958 120.968 166.475 1.00 325.07 ? 521 ILE R CG2 1 
ATOM 6498 C CD1 . ILE E 5 457 ? 166.182 123.368 167.844 1.00 325.68 ? 521 ILE R CD1 1 
ATOM 6499 N N   . GLU E 5 458 ? 170.136 120.686 165.203 1.00 321.28 ? 522 GLU R N   1 
ATOM 6500 C CA  . GLU E 5 458 ? 170.680 119.357 164.937 1.00 321.04 ? 522 GLU R CA  1 
ATOM 6501 C C   . GLU E 5 458 ? 172.017 119.140 165.636 1.00 320.69 ? 522 GLU R C   1 
ATOM 6502 O O   . GLU E 5 458 ? 172.358 117.999 165.975 1.00 320.18 ? 522 GLU R O   1 
ATOM 6503 C CB  . GLU E 5 458 ? 170.803 119.135 163.431 1.00 321.07 ? 522 GLU R CB  1 
ATOM 6504 C CG  . GLU E 5 458 ? 169.456 118.953 162.743 1.00 320.99 ? 522 GLU R CG  1 
ATOM 6505 C CD  . GLU E 5 458 ? 169.587 118.657 161.266 1.00 320.86 ? 522 GLU R CD  1 
ATOM 6506 O OE1 . GLU E 5 458 ? 170.624 119.028 160.676 1.00 320.78 ? 522 GLU R OE1 1 
ATOM 6507 O OE2 . GLU E 5 458 ? 168.654 118.048 160.699 1.00 320.85 ? 522 GLU R OE2 1 
ATOM 6508 N N   . LYS E 5 459 ? 172.784 120.219 165.853 1.00 316.97 ? 523 LYS R N   1 
ATOM 6509 C CA  . LYS E 5 459 ? 174.040 120.121 166.593 1.00 316.88 ? 523 LYS R CA  1 
ATOM 6510 C C   . LYS E 5 459 ? 173.885 120.386 168.087 1.00 317.14 ? 523 LYS R C   1 
ATOM 6511 O O   . LYS E 5 459 ? 174.878 120.308 168.819 1.00 317.17 ? 523 LYS R O   1 
ATOM 6512 C CB  . LYS E 5 459 ? 175.055 121.105 166.005 1.00 316.62 ? 523 LYS R CB  1 
ATOM 6513 C CG  . LYS E 5 459 ? 175.291 120.931 164.518 1.00 316.53 ? 523 LYS R CG  1 
ATOM 6514 C CD  . LYS E 5 459 ? 176.277 121.960 164.001 1.00 316.60 ? 523 LYS R CD  1 
ATOM 6515 C CE  . LYS E 5 459 ? 176.486 121.819 162.503 1.00 316.23 ? 523 LYS R CE  1 
ATOM 6516 N NZ  . LYS E 5 459 ? 177.466 122.811 161.982 1.00 316.27 ? 523 LYS R NZ  1 
ATOM 6517 N N   . ALA E 5 460 ? 172.675 120.691 168.555 1.00 329.44 ? 524 ALA R N   1 
ATOM 6518 C CA  . ALA E 5 460 ? 172.481 121.063 169.950 1.00 329.68 ? 524 ALA R CA  1 
ATOM 6519 C C   . ALA E 5 460 ? 172.763 119.893 170.887 1.00 330.00 ? 524 ALA R C   1 
ATOM 6520 O O   . ALA E 5 460 ? 172.550 118.725 170.548 1.00 329.82 ? 524 ALA R O   1 
ATOM 6521 C CB  . ALA E 5 460 ? 171.058 121.576 170.171 1.00 329.73 ? 524 ALA R CB  1 
ATOM 6522 N N   . ASP E 5 461 ? 173.255 120.223 172.082 1.00 335.60 ? 525 ASP R N   1 
ATOM 6523 C CA  . ASP E 5 461 ? 173.593 119.227 173.090 1.00 335.32 ? 525 ASP R CA  1 
ATOM 6524 C C   . ASP E 5 461 ? 172.519 119.051 174.155 1.00 335.21 ? 525 ASP R C   1 
ATOM 6525 O O   . ASP E 5 461 ? 172.409 117.964 174.733 1.00 334.96 ? 525 ASP R O   1 
ATOM 6526 C CB  . ASP E 5 461 ? 174.913 119.598 173.778 1.00 335.20 ? 525 ASP R CB  1 
ATOM 6527 C CG  . ASP E 5 461 ? 176.088 119.609 172.820 1.00 335.14 ? 525 ASP R CG  1 
ATOM 6528 O OD1 . ASP E 5 461 ? 176.187 118.688 171.982 1.00 334.99 ? 525 ASP R OD1 1 
ATOM 6529 O OD2 . ASP E 5 461 ? 176.912 120.544 172.907 1.00 335.17 ? 525 ASP R OD2 1 
ATOM 6530 N N   . ASN E 5 462 ? 171.723 120.082 174.433 1.00 340.43 ? 526 ASN R N   1 
ATOM 6531 C CA  . ASN E 5 462 ? 170.806 120.047 175.562 1.00 340.31 ? 526 ASN R CA  1 
ATOM 6532 C C   . ASN E 5 462 ? 169.524 120.795 175.208 1.00 340.47 ? 526 ASN R C   1 
ATOM 6533 O O   . ASN E 5 462 ? 169.387 121.408 174.123 1.00 340.85 ? 526 ASN R O   1 
ATOM 6534 C CB  . ASN E 5 462 ? 171.460 120.634 176.817 1.00 340.17 ? 526 ASN R CB  1 
ATOM 6535 C CG  . ASN E 5 462 ? 172.034 122.013 176.578 1.00 340.27 ? 526 ASN R CG  1 
ATOM 6536 O OD1 . ASN E 5 462 ? 171.310 123.008 176.580 1.00 340.52 ? 526 ASN R OD1 1 
ATOM 6537 N ND2 . ASN E 5 462 ? 173.344 122.079 176.372 1.00 340.01 ? 526 ASN R ND2 1 
ATOM 6538 N N   . ALA E 5 463 ? 168.570 120.754 176.145 1.00 342.57 ? 527 ALA R N   1 
ATOM 6539 C CA  . ALA E 5 463 ? 167.246 121.317 175.904 1.00 342.42 ? 527 ALA R CA  1 
ATOM 6540 C C   . ALA E 5 463 ? 167.280 122.830 175.726 1.00 343.01 ? 527 ALA R C   1 
ATOM 6541 O O   . ALA E 5 463 ? 166.431 123.382 175.019 1.00 343.46 ? 527 ALA R O   1 
ATOM 6542 C CB  . ALA E 5 463 ? 166.308 120.948 177.054 1.00 342.20 ? 527 ALA R CB  1 
ATOM 6543 N N   . ALA E 5 464 ? 168.233 123.518 176.361 1.00 345.17 ? 528 ALA R N   1 
ATOM 6544 C CA  . ALA E 5 464 ? 168.228 124.980 176.342 1.00 345.17 ? 528 ALA R CA  1 
ATOM 6545 C C   . ALA E 5 464 ? 168.528 125.529 174.952 1.00 345.50 ? 528 ALA R C   1 
ATOM 6546 O O   . ALA E 5 464 ? 167.847 126.447 174.477 1.00 345.63 ? 528 ALA R O   1 
ATOM 6547 C CB  . ALA E 5 464 ? 169.229 125.525 177.358 1.00 344.82 ? 528 ALA R CB  1 
ATOM 6548 N N   . GLN E 5 465 ? 169.552 124.989 174.286 1.00 345.68 ? 529 GLN R N   1 
ATOM 6549 C CA  . GLN E 5 465 ? 169.863 125.442 172.935 1.00 345.55 ? 529 GLN R CA  1 
ATOM 6550 C C   . GLN E 5 465 ? 168.723 125.121 171.986 1.00 345.94 ? 529 GLN R C   1 
ATOM 6551 O O   . GLN E 5 465 ? 168.396 125.923 171.098 1.00 346.09 ? 529 GLN R O   1 
ATOM 6552 C CB  . GLN E 5 465 ? 171.162 124.802 172.451 1.00 345.28 ? 529 GLN R CB  1 
ATOM 6553 C CG  . GLN E 5 465 ? 172.378 125.148 173.288 1.00 344.99 ? 529 GLN R CG  1 
ATOM 6554 C CD  . GLN E 5 465 ? 173.417 124.048 173.260 1.00 344.82 ? 529 GLN R CD  1 
ATOM 6555 O OE1 . GLN E 5 465 ? 173.107 122.885 173.512 1.00 345.18 ? 529 GLN R OE1 1 
ATOM 6556 N NE2 . GLN E 5 465 ? 174.655 124.406 172.941 1.00 344.44 ? 529 GLN R NE2 1 
ATOM 6557 N N   . VAL E 5 466 ? 168.107 123.939 172.170 1.00 355.74 ? 530 VAL R N   1 
ATOM 6558 C CA  . VAL E 5 466 ? 166.962 123.571 171.333 1.00 355.92 ? 530 VAL R CA  1 
ATOM 6559 C C   . VAL E 5 466 ? 165.822 124.570 171.504 1.00 356.18 ? 530 VAL R C   1 
ATOM 6560 O O   . VAL E 5 466 ? 165.236 125.045 170.527 1.00 356.52 ? 530 VAL R O   1 
ATOM 6561 C CB  . VAL E 5 466 ? 166.514 122.141 171.673 1.00 355.68 ? 530 VAL R CB  1 
ATOM 6562 C CG1 . VAL E 5 466 ? 165.258 121.762 170.910 1.00 355.91 ? 530 VAL R CG1 1 
ATOM 6563 C CG2 . VAL E 5 466 ? 167.632 121.160 171.381 1.00 355.32 ? 530 VAL R CG2 1 
ATOM 6564 N N   . LYS E 5 467 ? 165.503 124.906 172.756 1.00 358.90 ? 531 LYS R N   1 
ATOM 6565 C CA  . LYS E 5 467 ? 164.424 125.850 173.026 1.00 358.81 ? 531 LYS R CA  1 
ATOM 6566 C C   . LYS E 5 467 ? 164.734 127.231 172.457 1.00 359.12 ? 531 LYS R C   1 
ATOM 6567 O O   . LYS E 5 467 ? 163.854 127.884 171.887 1.00 359.69 ? 531 LYS R O   1 
ATOM 6568 C CB  . LYS E 5 467 ? 164.171 125.926 174.533 1.00 358.55 ? 531 LYS R CB  1 
ATOM 6569 C CG  . LYS E 5 467 ? 163.035 126.853 174.920 1.00 358.80 ? 531 LYS R CG  1 
ATOM 6570 C CD  . LYS E 5 467 ? 162.634 126.673 176.375 1.00 358.72 ? 531 LYS R CD  1 
ATOM 6571 C CE  . LYS E 5 467 ? 163.738 127.112 177.320 1.00 358.45 ? 531 LYS R CE  1 
ATOM 6572 N NZ  . LYS E 5 467 ? 164.062 128.557 177.157 1.00 358.45 ? 531 LYS R NZ  1 
ATOM 6573 N N   . ASP E 5 468 ? 165.977 127.696 172.605 1.00 363.79 ? 532 ASP R N   1 
ATOM 6574 C CA  . ASP E 5 468 ? 166.350 129.005 172.068 1.00 364.06 ? 532 ASP R CA  1 
ATOM 6575 C C   . ASP E 5 468 ? 166.234 129.033 170.546 1.00 364.16 ? 532 ASP R C   1 
ATOM 6576 O O   . ASP E 5 468 ? 165.645 129.960 169.964 1.00 364.79 ? 532 ASP R O   1 
ATOM 6577 C CB  . ASP E 5 468 ? 167.772 129.359 172.509 1.00 364.01 ? 532 ASP R CB  1 
ATOM 6578 C CG  . ASP E 5 468 ? 168.290 130.620 171.851 1.00 364.15 ? 532 ASP R CG  1 
ATOM 6579 O OD1 . ASP E 5 468 ? 167.748 131.710 172.135 1.00 364.24 ? 532 ASP R OD1 1 
ATOM 6580 O OD2 . ASP E 5 468 ? 169.242 130.521 171.050 1.00 364.08 ? 532 ASP R OD2 1 
ATOM 6581 N N   . ALA E 5 469 ? 166.795 128.019 169.882 1.00 358.15 ? 533 ALA R N   1 
ATOM 6582 C CA  . ALA E 5 469 ? 166.727 127.958 168.428 1.00 357.89 ? 533 ALA R CA  1 
ATOM 6583 C C   . ALA E 5 469 ? 165.287 127.846 167.951 1.00 358.41 ? 533 ALA R C   1 
ATOM 6584 O O   . ALA E 5 469 ? 164.926 128.420 166.921 1.00 359.14 ? 533 ALA R O   1 
ATOM 6585 C CB  . ALA E 5 469 ? 167.562 126.787 167.910 1.00 357.34 ? 533 ALA R CB  1 
ATOM 6586 N N   . LEU E 5 470 ? 164.445 127.116 168.684 1.00 366.28 ? 534 LEU R N   1 
ATOM 6587 C CA  . LEU E 5 470 ? 163.043 127.012 168.302 1.00 366.38 ? 534 LEU R CA  1 
ATOM 6588 C C   . LEU E 5 470 ? 162.294 128.314 168.550 1.00 366.95 ? 534 LEU R C   1 
ATOM 6589 O O   . LEU E 5 470 ? 161.330 128.614 167.843 1.00 367.20 ? 534 LEU R O   1 
ATOM 6590 C CB  . LEU E 5 470 ? 162.378 125.860 169.054 1.00 366.32 ? 534 LEU R CB  1 
ATOM 6591 C CG  . LEU E 5 470 ? 162.773 124.437 168.659 1.00 366.08 ? 534 LEU R CG  1 
ATOM 6592 C CD1 . LEU E 5 470 ? 162.376 123.477 169.758 1.00 366.23 ? 534 LEU R CD1 1 
ATOM 6593 C CD2 . LEU E 5 470 ? 162.136 124.033 167.341 1.00 366.07 ? 534 LEU R CD2 1 
ATOM 6594 N N   . THR E 5 471 ? 162.702 129.087 169.554 1.00 373.00 ? 535 THR R N   1 
ATOM 6595 C CA  . THR E 5 471 ? 162.125 130.412 169.754 1.00 372.81 ? 535 THR R CA  1 
ATOM 6596 C C   . THR E 5 471 ? 162.413 131.307 168.556 1.00 372.96 ? 535 THR R C   1 
ATOM 6597 O O   . THR E 5 471 ? 161.511 131.960 168.005 1.00 373.01 ? 535 THR R O   1 
ATOM 6598 C CB  . THR E 5 471 ? 162.688 131.028 171.037 1.00 372.42 ? 535 THR R CB  1 
ATOM 6599 O OG1 . THR E 5 471 ? 162.267 130.257 172.169 1.00 372.48 ? 535 THR R OG1 1 
ATOM 6600 C CG2 . THR E 5 471 ? 162.228 132.470 171.200 1.00 372.27 ? 535 THR R CG2 1 
ATOM 6601 N N   . LYS E 5 472 ? 163.676 131.329 168.128 1.00 366.70 ? 536 LYS R N   1 
ATOM 6602 C CA  . LYS E 5 472 ? 164.034 132.082 166.931 1.00 366.15 ? 536 LYS R CA  1 
ATOM 6603 C C   . LYS E 5 472 ? 163.311 131.540 165.704 1.00 366.10 ? 536 LYS R C   1 
ATOM 6604 O O   . LYS E 5 472 ? 162.897 132.307 164.826 1.00 365.89 ? 536 LYS R O   1 
ATOM 6605 C CB  . LYS E 5 472 ? 165.544 132.047 166.723 1.00 365.71 ? 536 LYS R CB  1 
ATOM 6606 C CG  . LYS E 5 472 ? 166.326 132.831 167.747 1.00 365.17 ? 536 LYS R CG  1 
ATOM 6607 C CD  . LYS E 5 472 ? 167.774 132.960 167.322 1.00 364.58 ? 536 LYS R CD  1 
ATOM 6608 C CE  . LYS E 5 472 ? 168.546 133.884 168.247 1.00 364.65 ? 536 LYS R CE  1 
ATOM 6609 N NZ  . LYS E 5 472 ? 168.514 133.403 169.654 1.00 364.81 ? 536 LYS R NZ  1 
ATOM 6610 N N   . MET E 5 473 ? 163.150 130.218 165.628 1.00 360.14 ? 537 MET R N   1 
ATOM 6611 C CA  . MET E 5 473 ? 162.383 129.608 164.550 1.00 359.55 ? 537 MET R CA  1 
ATOM 6612 C C   . MET E 5 473 ? 160.952 130.108 164.540 1.00 359.49 ? 537 MET R C   1 
ATOM 6613 O O   . MET E 5 473 ? 160.396 130.391 163.478 1.00 359.40 ? 537 MET R O   1 
ATOM 6614 C CB  . MET E 5 473 ? 162.376 128.091 164.701 1.00 359.14 ? 537 MET R CB  1 
ATOM 6615 C CG  . MET E 5 473 ? 163.520 127.356 164.073 1.00 358.76 ? 537 MET R CG  1 
ATOM 6616 S SD  . MET E 5 473 ? 163.258 125.589 164.261 1.00 358.81 ? 537 MET R SD  1 
ATOM 6617 C CE  . MET E 5 473 ? 164.890 124.981 163.908 1.00 357.75 ? 537 MET R CE  1 
ATOM 6618 N N   . ARG E 5 474 ? 160.324 130.174 165.711 1.00 368.63 ? 538 ARG R N   1 
ATOM 6619 C CA  . ARG E 5 474 ? 158.949 130.646 165.792 1.00 368.30 ? 538 ARG R CA  1 
ATOM 6620 C C   . ARG E 5 474 ? 158.843 132.077 165.298 1.00 368.66 ? 538 ARG R C   1 
ATOM 6621 O O   . ARG E 5 474 ? 157.966 132.405 164.491 1.00 368.91 ? 538 ARG R O   1 
ATOM 6622 C CB  . ARG E 5 474 ? 158.438 130.537 167.227 1.00 368.20 ? 538 ARG R CB  1 
ATOM 6623 C CG  . ARG E 5 474 ? 157.939 129.167 167.636 1.00 367.89 ? 538 ARG R CG  1 
ATOM 6624 C CD  . ARG E 5 474 ? 156.931 129.307 168.749 1.00 368.35 ? 538 ARG R CD  1 
ATOM 6625 N NE  . ARG E 5 474 ? 155.939 130.305 168.386 1.00 368.46 ? 538 ARG R NE  1 
ATOM 6626 C CZ  . ARG E 5 474 ? 154.705 130.032 167.988 1.00 368.18 ? 538 ARG R CZ  1 
ATOM 6627 N NH1 . ARG E 5 474 ? 154.235 128.800 167.991 1.00 367.73 ? 538 ARG R NH1 1 
ATOM 6628 N NH2 . ARG E 5 474 ? 153.921 131.024 167.580 1.00 368.23 ? 538 ARG R NH2 1 
ATOM 6629 N N   . ALA E 5 475 ? 159.750 132.942 165.756 1.00 365.24 ? 539 ALA R N   1 
ATOM 6630 C CA  . ALA E 5 475 ? 159.716 134.333 165.310 1.00 364.82 ? 539 ALA R CA  1 
ATOM 6631 C C   . ALA E 5 475 ? 159.885 134.427 163.798 1.00 364.52 ? 539 ALA R C   1 
ATOM 6632 O O   . ALA E 5 475 ? 159.092 135.084 163.110 1.00 364.61 ? 539 ALA R O   1 
ATOM 6633 C CB  . ALA E 5 475 ? 160.791 135.144 166.027 1.00 364.34 ? 539 ALA R CB  1 
ATOM 6634 N N   . ALA E 5 476 ? 160.899 133.738 163.260 1.00 344.91 ? 540 ALA R N   1 
ATOM 6635 C CA  . ALA E 5 476 ? 161.165 133.784 161.827 1.00 343.97 ? 540 ALA R CA  1 
ATOM 6636 C C   . ALA E 5 476 ? 160.001 133.222 161.027 1.00 343.91 ? 540 ALA R C   1 
ATOM 6637 O O   . ALA E 5 476 ? 159.661 133.748 159.965 1.00 343.76 ? 540 ALA R O   1 
ATOM 6638 C CB  . ALA E 5 476 ? 162.449 133.019 161.509 1.00 342.94 ? 540 ALA R CB  1 
ATOM 6639 N N   . ALA E 5 477 ? 159.392 132.143 161.509 1.00 345.52 ? 541 ALA R N   1 
ATOM 6640 C CA  . ALA E 5 477 ? 158.309 131.505 160.774 1.00 345.05 ? 541 ALA R CA  1 
ATOM 6641 C C   . ALA E 5 477 ? 157.067 132.380 160.748 1.00 345.21 ? 541 ALA R C   1 
ATOM 6642 O O   . ALA E 5 477 ? 156.396 132.473 159.716 1.00 344.97 ? 541 ALA R O   1 
ATOM 6643 C CB  . ALA E 5 477 ? 157.991 130.142 161.387 1.00 344.89 ? 541 ALA R CB  1 
ATOM 6644 N N   . LEU E 5 478 ? 156.738 133.027 161.868 1.00 351.01 ? 542 LEU R N   1 
ATOM 6645 C CA  . LEU E 5 478 ? 155.617 133.962 161.852 1.00 350.98 ? 542 LEU R CA  1 
ATOM 6646 C C   . LEU E 5 478 ? 155.898 135.130 160.913 1.00 351.15 ? 542 LEU R C   1 
ATOM 6647 O O   . LEU E 5 478 ? 155.021 135.549 160.140 1.00 351.55 ? 542 LEU R O   1 
ATOM 6648 C CB  . LEU E 5 478 ? 155.322 134.462 163.266 1.00 350.97 ? 542 LEU R CB  1 
ATOM 6649 C CG  . LEU E 5 478 ? 155.180 133.413 164.374 1.00 350.43 ? 542 LEU R CG  1 
ATOM 6650 C CD1 . LEU E 5 478 ? 155.080 134.068 165.734 1.00 350.45 ? 542 LEU R CD1 1 
ATOM 6651 C CD2 . LEU E 5 478 ? 154.001 132.514 164.133 1.00 350.10 ? 542 LEU R CD2 1 
ATOM 6652 N N   . ASP E 5 479 ? 157.131 135.647 160.936 1.00 335.20 ? 543 ASP R N   1 
ATOM 6653 C CA  . ASP E 5 479 ? 157.479 136.746 160.042 1.00 334.53 ? 543 ASP R CA  1 
ATOM 6654 C C   . ASP E 5 479 ? 157.357 136.334 158.578 1.00 333.55 ? 543 ASP R C   1 
ATOM 6655 O O   . ASP E 5 479 ? 156.787 137.072 157.753 1.00 333.39 ? 543 ASP R O   1 
ATOM 6656 C CB  . ASP E 5 479 ? 158.892 137.246 160.340 1.00 334.34 ? 543 ASP R CB  1 
ATOM 6657 C CG  . ASP E 5 479 ? 158.931 138.252 161.469 1.00 333.96 ? 543 ASP R CG  1 
ATOM 6658 O OD1 . ASP E 5 479 ? 157.850 138.693 161.913 1.00 334.33 ? 543 ASP R OD1 1 
ATOM 6659 O OD2 . ASP E 5 479 ? 160.043 138.604 161.910 1.00 333.32 ? 543 ASP R OD2 1 
ATOM 6660 N N   . ALA E 5 480 ? 157.868 135.151 158.234 1.00 310.60 ? 544 ALA R N   1 
ATOM 6661 C CA  . ALA E 5 480 ? 157.756 134.671 156.863 1.00 309.58 ? 544 ALA R CA  1 
ATOM 6662 C C   . ALA E 5 480 ? 156.303 134.426 156.484 1.00 309.60 ? 544 ALA R C   1 
ATOM 6663 O O   . ALA E 5 480 ? 155.886 134.720 155.357 1.00 309.58 ? 544 ALA R O   1 
ATOM 6664 C CB  . ALA E 5 480 ? 158.579 133.399 156.692 1.00 308.72 ? 544 ALA R CB  1 
ATOM 6665 N N   . GLN E 5 481 ? 155.517 133.889 157.415 1.00 300.92 ? 545 GLN R N   1 
ATOM 6666 C CA  . GLN E 5 481 ? 154.104 133.650 157.168 1.00 299.64 ? 545 GLN R CA  1 
ATOM 6667 C C   . GLN E 5 481 ? 153.385 134.943 156.832 1.00 299.10 ? 545 GLN R C   1 
ATOM 6668 O O   . GLN E 5 481 ? 152.415 134.938 156.065 1.00 298.17 ? 545 GLN R O   1 
ATOM 6669 C CB  . GLN E 5 481 ? 153.486 132.992 158.399 1.00 299.52 ? 545 GLN R CB  1 
ATOM 6670 C CG  . GLN E 5 481 ? 152.066 132.532 158.232 1.00 298.44 ? 545 GLN R CG  1 
ATOM 6671 C CD  . GLN E 5 481 ? 151.486 132.078 159.546 1.00 298.70 ? 545 GLN R CD  1 
ATOM 6672 O OE1 . GLN E 5 481 ? 152.077 132.313 160.602 1.00 298.96 ? 545 GLN R OE1 1 
ATOM 6673 N NE2 . GLN E 5 481 ? 150.330 131.424 159.498 1.00 298.87 ? 545 GLN R NE2 1 
ATOM 6674 N N   . LYS E 5 482 ? 153.839 136.055 157.403 1.00 285.83 ? 546 LYS R N   1 
ATOM 6675 C CA  . LYS E 5 482 ? 153.230 137.335 157.055 1.00 284.53 ? 546 LYS R CA  1 
ATOM 6676 C C   . LYS E 5 482 ? 153.603 137.776 155.640 1.00 284.80 ? 546 LYS R C   1 
ATOM 6677 O O   . LYS E 5 482 ? 152.746 138.274 154.897 1.00 284.64 ? 546 LYS R O   1 
ATOM 6678 C CB  . LYS E 5 482 ? 153.617 138.389 158.087 1.00 284.63 ? 546 LYS R CB  1 
ATOM 6679 C CG  . LYS E 5 482 ? 152.947 138.144 159.431 1.00 285.26 ? 546 LYS R CG  1 
ATOM 6680 C CD  . LYS E 5 482 ? 153.231 139.247 160.423 1.00 285.61 ? 546 LYS R CD  1 
ATOM 6681 C CE  . LYS E 5 482 ? 152.478 139.005 161.714 1.00 285.04 ? 546 LYS R CE  1 
ATOM 6682 N NZ  . LYS E 5 482 ? 151.028 138.834 161.466 1.00 284.02 ? 546 LYS R NZ  1 
ATOM 6683 N N   . ALA E 5 483 ? 154.865 137.591 155.248 1.00 260.51 ? 547 ALA R N   1 
ATOM 6684 C CA  . ALA E 5 483 ? 155.309 138.074 153.938 1.00 258.70 ? 547 ALA R CA  1 
ATOM 6685 C C   . ALA E 5 483 ? 154.662 137.291 152.795 1.00 257.99 ? 547 ALA R C   1 
ATOM 6686 O O   . ALA E 5 483 ? 154.354 136.108 152.921 1.00 258.30 ? 547 ALA R O   1 
ATOM 6687 C CB  . ALA E 5 483 ? 156.829 137.985 153.834 1.00 257.51 ? 547 ALA R CB  1 
ATOM 6688 N N   . THR E 5 484 ? 154.457 137.985 151.650 1.00 236.42 ? 548 THR R N   1 
ATOM 6689 C CA  . THR E 5 484 ? 153.855 137.465 150.421 1.00 236.41 ? 548 THR R CA  1 
ATOM 6690 C C   . THR E 5 484 ? 154.934 137.066 149.426 1.00 237.99 ? 548 THR R C   1 
ATOM 6691 O O   . THR E 5 484 ? 155.900 137.817 149.240 1.00 236.64 ? 548 THR R O   1 
ATOM 6692 C CB  . THR E 5 484 ? 152.939 138.517 149.792 1.00 235.44 ? 548 THR R CB  1 
ATOM 6693 O OG1 . THR E 5 484 ? 151.836 138.777 150.668 1.00 234.12 ? 548 THR R OG1 1 
ATOM 6694 C CG2 . THR E 5 484 ? 152.410 138.047 148.443 1.00 235.15 ? 548 THR R CG2 1 
ATOM 6695 N N   . PRO E 5 485 ? 154.833 135.896 148.774 1.00 258.25 ? 549 PRO R N   1 
ATOM 6696 C CA  . PRO E 5 485 ? 155.789 135.499 147.732 1.00 257.69 ? 549 PRO R CA  1 
ATOM 6697 C C   . PRO E 5 485 ? 155.884 136.513 146.594 1.00 256.45 ? 549 PRO R C   1 
ATOM 6698 O O   . PRO E 5 485 ? 154.966 136.580 145.775 1.00 254.97 ? 549 PRO R O   1 
ATOM 6699 C CB  . PRO E 5 485 ? 155.220 134.174 147.216 1.00 255.86 ? 549 PRO R CB  1 
ATOM 6700 C CG  . PRO E 5 485 ? 154.396 133.654 148.328 1.00 255.25 ? 549 PRO R CG  1 
ATOM 6701 C CD  . PRO E 5 485 ? 153.826 134.851 149.027 1.00 255.89 ? 549 PRO R CD  1 
ATOM 6702 N N   . MET E 5 498 ? 147.464 133.302 149.446 1.00 251.94 ? 562 MET R N   1 
ATOM 6703 C CA  . MET E 5 498 ? 148.210 133.153 150.690 1.00 253.21 ? 562 MET R CA  1 
ATOM 6704 C C   . MET E 5 498 ? 147.640 132.023 151.543 1.00 253.70 ? 562 MET R C   1 
ATOM 6705 O O   . MET E 5 498 ? 148.067 131.820 152.678 1.00 253.99 ? 562 MET R O   1 
ATOM 6706 C CB  . MET E 5 498 ? 148.199 134.463 151.484 1.00 253.11 ? 562 MET R CB  1 
ATOM 6707 C CG  . MET E 5 498 ? 148.738 135.665 150.722 1.00 253.13 ? 562 MET R CG  1 
ATOM 6708 S SD  . MET E 5 498 ? 150.525 135.620 150.484 1.00 252.36 ? 562 MET R SD  1 
ATOM 6709 C CE  . MET E 5 498 ? 151.100 135.732 152.177 1.00 252.27 ? 562 MET R CE  1 
ATOM 6710 N N   . LYS E 5 499 ? 146.662 131.298 150.994 1.00 237.19 ? 563 LYS R N   1 
ATOM 6711 C CA  . LYS E 5 499 ? 146.042 130.201 151.733 1.00 236.34 ? 563 LYS R CA  1 
ATOM 6712 C C   . LYS E 5 499 ? 147.049 129.092 152.022 1.00 236.54 ? 563 LYS R C   1 
ATOM 6713 O O   . LYS E 5 499 ? 147.373 128.813 153.183 1.00 236.49 ? 563 LYS R O   1 
ATOM 6714 C CB  . LYS E 5 499 ? 144.845 129.653 150.953 1.00 235.11 ? 563 LYS R CB  1 
ATOM 6715 C CG  . LYS E 5 499 ? 144.022 128.642 151.740 1.00 235.16 ? 563 LYS R CG  1 
ATOM 6716 C CD  . LYS E 5 499 ? 142.677 128.355 151.088 1.00 234.52 ? 563 LYS R CD  1 
ATOM 6717 C CE  . LYS E 5 499 ? 142.844 127.609 149.779 1.00 233.83 ? 563 LYS R CE  1 
ATOM 6718 N NZ  . LYS E 5 499 ? 143.555 126.317 149.974 1.00 233.58 ? 563 LYS R NZ  1 
ATOM 6719 N N   . ASP E 5 500 ? 147.565 128.454 150.969 1.00 251.76 ? 564 ASP R N   1 
ATOM 6720 C CA  . ASP E 5 500 ? 148.474 127.326 151.157 1.00 252.75 ? 564 ASP R CA  1 
ATOM 6721 C C   . ASP E 5 500 ? 149.827 127.776 151.685 1.00 253.55 ? 564 ASP R C   1 
ATOM 6722 O O   . ASP E 5 500 ? 150.491 127.020 152.399 1.00 255.18 ? 564 ASP R O   1 
ATOM 6723 C CB  . ASP E 5 500 ? 148.639 126.560 149.846 1.00 252.49 ? 564 ASP R CB  1 
ATOM 6724 C CG  . ASP E 5 500 ? 147.311 126.171 149.229 1.00 253.08 ? 564 ASP R CG  1 
ATOM 6725 O OD1 . ASP E 5 500 ? 146.381 125.837 149.992 1.00 253.04 ? 564 ASP R OD1 1 
ATOM 6726 O OD2 . ASP E 5 500 ? 147.192 126.210 147.985 1.00 253.21 ? 564 ASP R OD2 1 
ATOM 6727 N N   . PHE E 5 501 ? 150.237 129.002 151.360 1.00 254.36 ? 565 PHE R N   1 
ATOM 6728 C CA  . PHE E 5 501 ? 151.445 129.588 151.929 1.00 254.26 ? 565 PHE R CA  1 
ATOM 6729 C C   . PHE E 5 501 ? 151.377 129.603 153.454 1.00 254.91 ? 565 PHE R C   1 
ATOM 6730 O O   . PHE E 5 501 ? 152.197 128.983 154.151 1.00 254.82 ? 565 PHE R O   1 
ATOM 6731 C CB  . PHE E 5 501 ? 151.600 131.002 151.366 1.00 253.72 ? 565 PHE R CB  1 
ATOM 6732 C CG  . PHE E 5 501 ? 152.853 131.701 151.780 1.00 253.21 ? 565 PHE R CG  1 
ATOM 6733 C CD1 . PHE E 5 501 ? 154.010 131.553 151.041 1.00 253.72 ? 565 PHE R CD1 1 
ATOM 6734 C CD2 . PHE E 5 501 ? 152.866 132.535 152.885 1.00 253.36 ? 565 PHE R CD2 1 
ATOM 6735 C CE1 . PHE E 5 501 ? 155.169 132.202 151.406 1.00 253.62 ? 565 PHE R CE1 1 
ATOM 6736 C CE2 . PHE E 5 501 ? 154.022 133.186 153.259 1.00 254.14 ? 565 PHE R CE2 1 
ATOM 6737 C CZ  . PHE E 5 501 ? 155.175 133.025 152.514 1.00 253.74 ? 565 PHE R CZ  1 
ATOM 6738 N N   . ARG E 5 502 ? 150.372 130.292 153.990 1.00 260.30 ? 566 ARG R N   1 
ATOM 6739 C CA  . ARG E 5 502 ? 150.238 130.368 155.434 1.00 260.26 ? 566 ARG R CA  1 
ATOM 6740 C C   . ARG E 5 502 ? 149.894 129.016 156.043 1.00 261.08 ? 566 ARG R C   1 
ATOM 6741 O O   . ARG E 5 502 ? 150.220 128.776 157.203 1.00 261.71 ? 566 ARG R O   1 
ATOM 6742 C CB  . ARG E 5 502 ? 149.200 131.427 155.800 1.00 259.16 ? 566 ARG R CB  1 
ATOM 6743 C CG  . ARG E 5 502 ? 149.706 132.824 155.492 1.00 258.63 ? 566 ARG R CG  1 
ATOM 6744 C CD  . ARG E 5 502 ? 148.653 133.904 155.608 1.00 258.51 ? 566 ARG R CD  1 
ATOM 6745 N NE  . ARG E 5 502 ? 149.245 135.204 155.316 1.00 258.56 ? 566 ARG R NE  1 
ATOM 6746 C CZ  . ARG E 5 502 ? 148.563 136.331 155.171 1.00 258.91 ? 566 ARG R CZ  1 
ATOM 6747 N NH1 . ARG E 5 502 ? 147.246 136.362 155.289 1.00 258.64 ? 566 ARG R NH1 1 
ATOM 6748 N NH2 . ARG E 5 502 ? 149.218 137.455 154.896 1.00 258.90 ? 566 ARG R NH2 1 
ATOM 6749 N N   . HIS E 5 503 ? 149.245 128.124 155.292 1.00 272.15 ? 567 HIS R N   1 
ATOM 6750 C CA  . HIS E 5 503 ? 148.997 126.776 155.800 1.00 272.27 ? 567 HIS R CA  1 
ATOM 6751 C C   . HIS E 5 503 ? 150.302 126.009 155.998 1.00 272.68 ? 567 HIS R C   1 
ATOM 6752 O O   . HIS E 5 503 ? 150.508 125.352 157.028 1.00 272.96 ? 567 HIS R O   1 
ATOM 6753 C CB  . HIS E 5 503 ? 148.072 126.025 154.845 1.00 271.55 ? 567 HIS R CB  1 
ATOM 6754 C CG  . HIS E 5 503 ? 147.910 124.576 155.178 1.00 271.81 ? 567 HIS R CG  1 
ATOM 6755 N ND1 . HIS E 5 503 ? 147.056 124.128 156.162 1.00 271.51 ? 567 HIS R ND1 1 
ATOM 6756 C CD2 . HIS E 5 503 ? 148.497 123.473 154.659 1.00 272.23 ? 567 HIS R CD2 1 
ATOM 6757 C CE1 . HIS E 5 503 ? 147.121 122.811 156.232 1.00 271.95 ? 567 HIS R CE1 1 
ATOM 6758 N NE2 . HIS E 5 503 ? 147.989 122.388 155.331 1.00 272.28 ? 567 HIS R NE2 1 
ATOM 6759 N N   . GLY E 5 504 ? 151.195 126.073 155.012 1.00 279.94 ? 568 GLY R N   1 
ATOM 6760 C CA  . GLY E 5 504 ? 152.501 125.465 155.176 1.00 279.65 ? 568 GLY R CA  1 
ATOM 6761 C C   . GLY E 5 504 ? 153.257 126.050 156.350 1.00 279.81 ? 568 GLY R C   1 
ATOM 6762 O O   . GLY E 5 504 ? 153.950 125.334 157.080 1.00 280.76 ? 568 GLY R O   1 
ATOM 6763 N N   . PHE E 5 505 ? 153.118 127.359 156.568 1.00 284.60 ? 569 PHE R N   1 
ATOM 6764 C CA  . PHE E 5 505 ? 153.797 127.941 157.728 1.00 285.17 ? 569 PHE R CA  1 
ATOM 6765 C C   . PHE E 5 505 ? 153.100 127.597 159.042 1.00 286.44 ? 569 PHE R C   1 
ATOM 6766 O O   . PHE E 5 505 ? 153.752 127.554 160.091 1.00 287.47 ? 569 PHE R O   1 
ATOM 6767 C CB  . PHE E 5 505 ? 153.943 129.445 157.557 1.00 285.04 ? 569 PHE R CB  1 
ATOM 6768 C CG  . PHE E 5 505 ? 155.037 129.822 156.614 1.00 285.40 ? 569 PHE R CG  1 
ATOM 6769 C CD1 . PHE E 5 505 ? 156.339 129.959 157.061 1.00 284.72 ? 569 PHE R CD1 1 
ATOM 6770 C CD2 . PHE E 5 505 ? 154.772 130.001 155.271 1.00 285.92 ? 569 PHE R CD2 1 
ATOM 6771 C CE1 . PHE E 5 505 ? 157.347 130.288 156.187 1.00 284.70 ? 569 PHE R CE1 1 
ATOM 6772 C CE2 . PHE E 5 505 ? 155.774 130.328 154.396 1.00 285.25 ? 569 PHE R CE2 1 
ATOM 6773 C CZ  . PHE E 5 505 ? 157.061 130.476 154.854 1.00 284.65 ? 569 PHE R CZ  1 
ATOM 6774 N N   . ASP E 5 506 ? 151.793 127.339 159.008 1.00 297.99 ? 570 ASP R N   1 
ATOM 6775 C CA  . ASP E 5 506 ? 151.114 126.773 160.164 1.00 298.29 ? 570 ASP R CA  1 
ATOM 6776 C C   . ASP E 5 506 ? 151.713 125.424 160.521 1.00 298.45 ? 570 ASP R C   1 
ATOM 6777 O O   . ASP E 5 506 ? 151.948 125.129 161.697 1.00 298.82 ? 570 ASP R O   1 
ATOM 6778 C CB  . ASP E 5 506 ? 149.620 126.632 159.877 1.00 298.27 ? 570 ASP R CB  1 
ATOM 6779 C CG  . ASP E 5 506 ? 148.918 127.963 159.783 1.00 298.34 ? 570 ASP R CG  1 
ATOM 6780 O OD1 . ASP E 5 506 ? 149.291 128.888 160.533 1.00 298.56 ? 570 ASP R OD1 1 
ATOM 6781 O OD2 . ASP E 5 506 ? 147.992 128.087 158.957 1.00 298.44 ? 570 ASP R OD2 1 
ATOM 6782 N N   . ILE E 5 507 ? 151.981 124.600 159.508 1.00 298.32 ? 571 ILE R N   1 
ATOM 6783 C CA  . ILE E 5 507 ? 152.606 123.303 159.757 1.00 298.03 ? 571 ILE R CA  1 
ATOM 6784 C C   . ILE E 5 507 ? 154.015 123.482 160.315 1.00 298.80 ? 571 ILE R C   1 
ATOM 6785 O O   . ILE E 5 507 ? 154.424 122.775 161.245 1.00 298.97 ? 571 ILE R O   1 
ATOM 6786 C CB  . ILE E 5 507 ? 152.603 122.453 158.475 1.00 297.39 ? 571 ILE R CB  1 
ATOM 6787 C CG1 . ILE E 5 507 ? 151.169 122.238 157.995 1.00 297.02 ? 571 ILE R CG1 1 
ATOM 6788 C CG2 . ILE E 5 507 ? 153.287 121.116 158.718 1.00 297.35 ? 571 ILE R CG2 1 
ATOM 6789 C CD1 . ILE E 5 507 ? 151.072 121.472 156.702 1.00 297.21 ? 571 ILE R CD1 1 
ATOM 6790 N N   . LEU E 5 508 ? 154.779 124.423 159.757 1.00 315.33 ? 572 LEU R N   1 
ATOM 6791 C CA  . LEU E 5 508 ? 156.121 124.685 160.273 1.00 315.63 ? 572 LEU R CA  1 
ATOM 6792 C C   . LEU E 5 508 ? 156.082 125.103 161.739 1.00 316.53 ? 572 LEU R C   1 
ATOM 6793 O O   . LEU E 5 508 ? 156.851 124.597 162.563 1.00 317.13 ? 572 LEU R O   1 
ATOM 6794 C CB  . LEU E 5 508 ? 156.815 125.761 159.441 1.00 315.59 ? 572 LEU R CB  1 
ATOM 6795 C CG  . LEU E 5 508 ? 157.420 125.417 158.083 1.00 315.49 ? 572 LEU R CG  1 
ATOM 6796 C CD1 . LEU E 5 508 ? 157.827 126.698 157.384 1.00 314.74 ? 572 LEU R CD1 1 
ATOM 6797 C CD2 . LEU E 5 508 ? 158.617 124.492 158.233 1.00 315.51 ? 572 LEU R CD2 1 
ATOM 6798 N N   . VAL E 5 509 ? 155.187 126.031 162.085 1.00 339.61 ? 573 VAL R N   1 
ATOM 6799 C CA  . VAL E 5 509 ? 155.113 126.513 163.461 1.00 340.12 ? 573 VAL R CA  1 
ATOM 6800 C C   . VAL E 5 509 ? 154.628 125.411 164.394 1.00 340.38 ? 573 VAL R C   1 
ATOM 6801 O O   . VAL E 5 509 ? 155.107 125.290 165.523 1.00 341.26 ? 573 VAL R O   1 
ATOM 6802 C CB  . VAL E 5 509 ? 154.218 127.763 163.541 1.00 339.94 ? 573 VAL R CB  1 
ATOM 6803 C CG1 . VAL E 5 509 ? 153.866 128.063 164.970 1.00 340.06 ? 573 VAL R CG1 1 
ATOM 6804 C CG2 . VAL E 5 509 ? 154.927 128.949 162.927 1.00 340.35 ? 573 VAL R CG2 1 
ATOM 6805 N N   . GLY E 5 510 ? 153.667 124.599 163.946 1.00 341.34 ? 574 GLY R N   1 
ATOM 6806 C CA  . GLY E 5 510 ? 153.213 123.485 164.762 1.00 341.51 ? 574 GLY R CA  1 
ATOM 6807 C C   . GLY E 5 510 ? 154.307 122.473 165.038 1.00 341.62 ? 574 GLY R C   1 
ATOM 6808 O O   . GLY E 5 510 ? 154.413 121.946 166.148 1.00 342.09 ? 574 GLY R O   1 
ATOM 6809 N N   . GLN E 5 511 ? 155.129 122.174 164.032 1.00 333.70 ? 575 GLN R N   1 
ATOM 6810 C CA  . GLN E 5 511 ? 156.252 121.269 164.255 1.00 333.71 ? 575 GLN R CA  1 
ATOM 6811 C C   . GLN E 5 511 ? 157.288 121.891 165.183 1.00 334.49 ? 575 GLN R C   1 
ATOM 6812 O O   . GLN E 5 511 ? 157.885 121.197 166.017 1.00 334.77 ? 575 GLN R O   1 
ATOM 6813 C CB  . GLN E 5 511 ? 156.878 120.879 162.918 1.00 333.01 ? 575 GLN R CB  1 
ATOM 6814 C CG  . GLN E 5 511 ? 155.966 120.039 162.043 1.00 333.03 ? 575 GLN R CG  1 
ATOM 6815 C CD  . GLN E 5 511 ? 156.503 119.876 160.637 1.00 332.45 ? 575 GLN R CD  1 
ATOM 6816 O OE1 . GLN E 5 511 ? 157.419 120.588 160.227 1.00 332.05 ? 575 GLN R OE1 1 
ATOM 6817 N NE2 . GLN E 5 511 ? 155.935 118.936 159.889 1.00 332.77 ? 575 GLN R NE2 1 
ATOM 6818 N N   . ILE E 5 512 ? 157.512 123.200 165.057 1.00 363.76 ? 576 ILE R N   1 
ATOM 6819 C CA  . ILE E 5 512 ? 158.393 123.894 165.992 1.00 364.50 ? 576 ILE R CA  1 
ATOM 6820 C C   . ILE E 5 512 ? 157.838 123.808 167.409 1.00 364.90 ? 576 ILE R C   1 
ATOM 6821 O O   . ILE E 5 512 ? 158.585 123.642 168.377 1.00 365.44 ? 576 ILE R O   1 
ATOM 6822 C CB  . ILE E 5 512 ? 158.593 125.354 165.544 1.00 364.77 ? 576 ILE R CB  1 
ATOM 6823 C CG1 . ILE E 5 512 ? 159.335 125.394 164.207 1.00 364.38 ? 576 ILE R CG1 1 
ATOM 6824 C CG2 . ILE E 5 512 ? 159.357 126.139 166.596 1.00 364.86 ? 576 ILE R CG2 1 
ATOM 6825 C CD1 . ILE E 5 512 ? 159.195 126.699 163.455 1.00 364.30 ? 576 ILE R CD1 1 
ATOM 6826 N N   . ASP E 5 513 ? 156.517 123.916 167.548 1.00 375.59 ? 577 ASP R N   1 
ATOM 6827 C CA  . ASP E 5 513 ? 155.876 123.797 168.853 1.00 375.71 ? 577 ASP R CA  1 
ATOM 6828 C C   . ASP E 5 513 ? 156.007 122.391 169.419 1.00 375.86 ? 577 ASP R C   1 
ATOM 6829 O O   . ASP E 5 513 ? 156.192 122.220 170.627 1.00 376.54 ? 577 ASP R O   1 
ATOM 6830 C CB  . ASP E 5 513 ? 154.406 124.190 168.747 1.00 375.67 ? 577 ASP R CB  1 
ATOM 6831 C CG  . ASP E 5 513 ? 154.220 125.678 168.685 1.00 375.54 ? 577 ASP R CG  1 
ATOM 6832 O OD1 . ASP E 5 513 ? 155.229 126.386 168.869 1.00 375.83 ? 577 ASP R OD1 1 
ATOM 6833 O OD2 . ASP E 5 513 ? 153.083 126.138 168.459 1.00 375.50 ? 577 ASP R OD2 1 
ATOM 6834 N N   . ASP E 5 514 ? 155.872 121.370 168.571 1.00 373.23 ? 578 ASP R N   1 
ATOM 6835 C CA  . ASP E 5 514 ? 156.074 120.001 169.034 1.00 373.29 ? 578 ASP R CA  1 
ATOM 6836 C C   . ASP E 5 514 ? 157.498 119.804 169.526 1.00 373.29 ? 578 ASP R C   1 
ATOM 6837 O O   . ASP E 5 514 ? 157.728 119.190 170.578 1.00 373.90 ? 578 ASP R O   1 
ATOM 6838 C CB  . ASP E 5 514 ? 155.759 119.011 167.918 1.00 372.74 ? 578 ASP R CB  1 
ATOM 6839 C CG  . ASP E 5 514 ? 154.278 118.806 167.724 1.00 372.60 ? 578 ASP R CG  1 
ATOM 6840 O OD1 . ASP E 5 514 ? 153.489 119.436 168.459 1.00 372.96 ? 578 ASP R OD1 1 
ATOM 6841 O OD2 . ASP E 5 514 ? 153.902 118.011 166.837 1.00 372.09 ? 578 ASP R OD2 1 
ATOM 6842 N N   . ALA E 5 515 ? 158.466 120.335 168.783 1.00 371.63 ? 579 ALA R N   1 
ATOM 6843 C CA  . ALA E 5 515 ? 159.852 120.261 169.224 1.00 371.32 ? 579 ALA R CA  1 
ATOM 6844 C C   . ALA E 5 515 ? 160.054 121.022 170.525 1.00 371.77 ? 579 ALA R C   1 
ATOM 6845 O O   . ALA E 5 515 ? 160.827 120.595 171.386 1.00 371.83 ? 579 ALA R O   1 
ATOM 6846 C CB  . ALA E 5 515 ? 160.777 120.792 168.131 1.00 370.81 ? 579 ALA R CB  1 
ATOM 6847 N N   . LEU E 5 516 ? 159.368 122.153 170.689 1.00 377.66 ? 580 LEU R N   1 
ATOM 6848 C CA  . LEU E 5 516 ? 159.470 122.908 171.935 1.00 377.35 ? 580 LEU R CA  1 
ATOM 6849 C C   . LEU E 5 516 ? 158.880 122.137 173.109 1.00 377.63 ? 580 LEU R C   1 
ATOM 6850 O O   . LEU E 5 516 ? 159.444 122.143 174.207 1.00 377.63 ? 580 LEU R O   1 
ATOM 6851 C CB  . LEU E 5 516 ? 158.781 124.262 171.782 1.00 377.38 ? 580 LEU R CB  1 
ATOM 6852 C CG  . LEU E 5 516 ? 159.688 125.399 171.311 1.00 377.23 ? 580 LEU R CG  1 
ATOM 6853 C CD1 . LEU E 5 516 ? 158.878 126.637 170.978 1.00 377.36 ? 580 LEU R CD1 1 
ATOM 6854 C CD2 . LEU E 5 516 ? 160.766 125.717 172.343 1.00 377.04 ? 580 LEU R CD2 1 
ATOM 6855 N N   . LYS E 5 517 ? 157.738 121.484 172.901 1.00 379.20 ? 581 LYS R N   1 
ATOM 6856 C CA  . LYS E 5 517 ? 157.147 120.669 173.956 1.00 378.87 ? 581 LYS R CA  1 
ATOM 6857 C C   . LYS E 5 517 ? 158.083 119.542 174.361 1.00 378.45 ? 581 LYS R C   1 
ATOM 6858 O O   . LYS E 5 517 ? 158.268 119.264 175.561 1.00 378.49 ? 581 LYS R O   1 
ATOM 6859 C CB  . LYS E 5 517 ? 155.807 120.093 173.506 1.00 378.85 ? 581 LYS R CB  1 
ATOM 6860 C CG  . LYS E 5 517 ? 154.651 121.053 173.620 1.00 378.53 ? 581 LYS R CG  1 
ATOM 6861 C CD  . LYS E 5 517 ? 153.332 120.356 173.361 1.00 378.31 ? 581 LYS R CD  1 
ATOM 6862 C CE  . LYS E 5 517 ? 153.303 119.724 171.983 1.00 378.38 ? 581 LYS R CE  1 
ATOM 6863 N NZ  . LYS E 5 517 ? 152.008 119.038 171.717 1.00 378.03 ? 581 LYS R NZ  1 
ATOM 6864 N N   . LEU E 5 518 ? 158.691 118.882 173.375 1.00 365.23 ? 582 LEU R N   1 
ATOM 6865 C CA  . LEU E 5 518 ? 159.636 117.817 173.690 1.00 364.41 ? 582 LEU R CA  1 
ATOM 6866 C C   . LEU E 5 518 ? 160.871 118.361 174.404 1.00 364.34 ? 582 LEU R C   1 
ATOM 6867 O O   . LEU E 5 518 ? 161.374 117.735 175.344 1.00 364.58 ? 582 LEU R O   1 
ATOM 6868 C CB  . LEU E 5 518 ? 160.014 117.069 172.413 1.00 363.99 ? 582 LEU R CB  1 
ATOM 6869 C CG  . LEU E 5 518 ? 158.776 116.435 171.772 1.00 364.13 ? 582 LEU R CG  1 
ATOM 6870 C CD1 . LEU E 5 518 ? 159.104 115.702 170.480 1.00 363.96 ? 582 LEU R CD1 1 
ATOM 6871 C CD2 . LEU E 5 518 ? 158.088 115.512 172.766 1.00 363.86 ? 582 LEU R CD2 1 
ATOM 6872 N N   . ALA E 5 519 ? 161.366 119.529 173.984 1.00 362.43 ? 583 ALA R N   1 
ATOM 6873 C CA  . ALA E 5 519 ? 162.551 120.109 174.610 1.00 361.97 ? 583 ALA R CA  1 
ATOM 6874 C C   . ALA E 5 519 ? 162.282 120.518 176.053 1.00 362.32 ? 583 ALA R C   1 
ATOM 6875 O O   . ALA E 5 519 ? 163.138 120.332 176.925 1.00 361.66 ? 583 ALA R O   1 
ATOM 6876 C CB  . ALA E 5 519 ? 163.036 121.311 173.800 1.00 361.94 ? 583 ALA R CB  1 
ATOM 6877 N N   . ASN E 5 520 ? 161.105 121.090 176.319 1.00 371.40 ? 584 ASN R N   1 
ATOM 6878 C CA  . ASN E 5 520 ? 160.780 121.528 177.672 1.00 371.34 ? 584 ASN R CA  1 
ATOM 6879 C C   . ASN E 5 520 ? 160.636 120.352 178.627 1.00 371.22 ? 584 ASN R C   1 
ATOM 6880 O O   . ASN E 5 520 ? 160.825 120.515 179.840 1.00 371.02 ? 584 ASN R O   1 
ATOM 6881 C CB  . ASN E 5 520 ? 159.500 122.363 177.661 1.00 371.43 ? 584 ASN R CB  1 
ATOM 6882 C CG  . ASN E 5 520 ? 159.748 123.807 177.267 1.00 371.42 ? 584 ASN R CG  1 
ATOM 6883 O OD1 . ASN E 5 520 ? 160.787 124.382 177.591 1.00 371.43 ? 584 ASN R OD1 1 
ATOM 6884 N ND2 . ASN E 5 520 ? 158.789 124.402 176.568 1.00 371.31 ? 584 ASN R ND2 1 
ATOM 6885 N N   . GLU E 5 521 ? 160.292 119.171 178.104 1.00 362.49 ? 585 GLU R N   1 
ATOM 6886 C CA  . GLU E 5 521 ? 160.213 117.975 178.936 1.00 361.66 ? 585 GLU R CA  1 
ATOM 6887 C C   . GLU E 5 521 ? 161.551 117.271 179.110 1.00 361.18 ? 585 GLU R C   1 
ATOM 6888 O O   . GLU E 5 521 ? 161.608 116.246 179.795 1.00 361.00 ? 585 GLU R O   1 
ATOM 6889 C CB  . GLU E 5 521 ? 159.202 116.993 178.342 1.00 361.59 ? 585 GLU R CB  1 
ATOM 6890 C CG  . GLU E 5 521 ? 157.792 117.524 178.226 1.00 362.14 ? 585 GLU R CG  1 
ATOM 6891 C CD  . GLU E 5 521 ? 156.901 116.574 177.459 1.00 361.79 ? 585 GLU R CD  1 
ATOM 6892 O OE1 . GLU E 5 521 ? 157.414 115.543 176.982 1.00 361.25 ? 585 GLU R OE1 1 
ATOM 6893 O OE2 . GLU E 5 521 ? 155.692 116.849 177.325 1.00 362.06 ? 585 GLU R OE2 1 
ATOM 6894 N N   . GLY E 5 522 ? 162.623 117.790 178.512 1.00 351.64 ? 586 GLY R N   1 
ATOM 6895 C CA  . GLY E 5 522 ? 163.917 117.141 178.555 1.00 351.26 ? 586 GLY R CA  1 
ATOM 6896 C C   . GLY E 5 522 ? 164.159 116.112 177.470 1.00 351.30 ? 586 GLY R C   1 
ATOM 6897 O O   . GLY E 5 522 ? 165.213 115.464 177.481 1.00 351.13 ? 586 GLY R O   1 
ATOM 6898 N N   . LYS E 5 523 ? 163.218 115.936 176.541 1.00 347.90 ? 587 LYS R N   1 
ATOM 6899 C CA  . LYS E 5 523 ? 163.372 115.001 175.423 1.00 347.61 ? 587 LYS R CA  1 
ATOM 6900 C C   . LYS E 5 523 ? 164.075 115.714 174.268 1.00 347.55 ? 587 LYS R C   1 
ATOM 6901 O O   . LYS E 5 523 ? 163.468 116.128 173.271 1.00 347.56 ? 587 LYS R O   1 
ATOM 6902 C CB  . LYS E 5 523 ? 162.015 114.448 175.005 1.00 347.39 ? 587 LYS R CB  1 
ATOM 6903 C CG  . LYS E 5 523 ? 161.243 113.765 176.128 1.00 347.50 ? 587 LYS R CG  1 
ATOM 6904 C CD  . LYS E 5 523 ? 159.837 113.383 175.682 1.00 347.57 ? 587 LYS R CD  1 
ATOM 6905 C CE  . LYS E 5 523 ? 159.021 112.812 176.832 1.00 347.53 ? 587 LYS R CE  1 
ATOM 6906 N NZ  . LYS E 5 523 ? 157.606 112.566 176.439 1.00 347.18 ? 587 LYS R NZ  1 
ATOM 6907 N N   . VAL E 5 524 ? 165.396 115.850 174.412 1.00 336.09 ? 588 VAL R N   1 
ATOM 6908 C CA  . VAL E 5 524 ? 166.181 116.630 173.457 1.00 335.74 ? 588 VAL R CA  1 
ATOM 6909 C C   . VAL E 5 524 ? 166.160 115.980 172.077 1.00 335.83 ? 588 VAL R C   1 
ATOM 6910 O O   . VAL E 5 524 ? 165.951 116.652 171.059 1.00 335.97 ? 588 VAL R O   1 
ATOM 6911 C CB  . VAL E 5 524 ? 167.621 116.811 173.971 1.00 335.17 ? 588 VAL R CB  1 
ATOM 6912 C CG1 . VAL E 5 524 ? 168.418 117.678 173.011 1.00 335.19 ? 588 VAL R CG1 1 
ATOM 6913 C CG2 . VAL E 5 524 ? 167.620 117.412 175.372 1.00 335.17 ? 588 VAL R CG2 1 
ATOM 6914 N N   . LYS E 5 525 ? 166.387 114.665 172.018 1.00 328.88 ? 589 LYS R N   1 
ATOM 6915 C CA  . LYS E 5 525 ? 166.502 113.991 170.726 1.00 328.73 ? 589 LYS R CA  1 
ATOM 6916 C C   . LYS E 5 525 ? 165.165 113.953 169.991 1.00 329.38 ? 589 LYS R C   1 
ATOM 6917 O O   . LYS E 5 525 ? 165.119 114.106 168.762 1.00 329.52 ? 589 LYS R O   1 
ATOM 6918 C CB  . LYS E 5 525 ? 167.061 112.582 170.921 1.00 328.00 ? 589 LYS R CB  1 
ATOM 6919 C CG  . LYS E 5 525 ? 168.454 112.565 171.535 1.00 327.77 ? 589 LYS R CG  1 
ATOM 6920 C CD  . LYS E 5 525 ? 169.010 111.154 171.639 1.00 327.90 ? 589 LYS R CD  1 
ATOM 6921 C CE  . LYS E 5 525 ? 170.388 111.149 172.289 1.00 327.94 ? 589 LYS R CE  1 
ATOM 6922 N NZ  . LYS E 5 525 ? 170.982 109.783 172.362 1.00 327.53 ? 589 LYS R NZ  1 
ATOM 6923 N N   . GLU E 5 526 ? 164.067 113.746 170.719 1.00 338.85 ? 590 GLU R N   1 
ATOM 6924 C CA  . GLU E 5 526 ? 162.753 113.777 170.083 1.00 338.78 ? 590 GLU R CA  1 
ATOM 6925 C C   . GLU E 5 526 ? 162.421 115.177 169.584 1.00 339.25 ? 590 GLU R C   1 
ATOM 6926 O O   . GLU E 5 526 ? 161.785 115.338 168.534 1.00 339.39 ? 590 GLU R O   1 
ATOM 6927 C CB  . GLU E 5 526 ? 161.688 113.278 171.055 1.00 338.23 ? 590 GLU R CB  1 
ATOM 6928 C CG  . GLU E 5 526 ? 161.898 111.845 171.506 1.00 338.45 ? 590 GLU R CG  1 
ATOM 6929 C CD  . GLU E 5 526 ? 160.774 111.337 172.384 1.00 338.69 ? 590 GLU R CD  1 
ATOM 6930 O OE1 . GLU E 5 526 ? 159.796 112.086 172.590 1.00 338.71 ? 590 GLU R OE1 1 
ATOM 6931 O OE2 . GLU E 5 526 ? 160.868 110.189 172.867 1.00 338.73 ? 590 GLU R OE2 1 
ATOM 6932 N N   . ALA E 5 527 ? 162.851 116.204 170.325 1.00 341.76 ? 591 ALA R N   1 
ATOM 6933 C CA  . ALA E 5 527 ? 162.721 117.570 169.829 1.00 341.74 ? 591 ALA R CA  1 
ATOM 6934 C C   . ALA E 5 527 ? 163.516 117.766 168.545 1.00 341.36 ? 591 ALA R C   1 
ATOM 6935 O O   . ALA E 5 527 ? 163.052 118.427 167.609 1.00 341.44 ? 591 ALA R O   1 
ATOM 6936 C CB  . ALA E 5 527 ? 163.182 118.554 170.901 1.00 341.75 ? 591 ALA R CB  1 
ATOM 6937 N N   . GLN E 5 528 ? 164.721 117.197 168.485 1.00 326.66 ? 592 GLN R N   1 
ATOM 6938 C CA  . GLN E 5 528 ? 165.530 117.299 167.274 1.00 325.97 ? 592 GLN R CA  1 
ATOM 6939 C C   . GLN E 5 528 ? 164.849 116.615 166.094 1.00 326.03 ? 592 GLN R C   1 
ATOM 6940 O O   . GLN E 5 528 ? 164.899 117.114 164.967 1.00 325.74 ? 592 GLN R O   1 
ATOM 6941 C CB  . GLN E 5 528 ? 166.919 116.710 167.522 1.00 325.63 ? 592 GLN R CB  1 
ATOM 6942 C CG  . GLN E 5 528 ? 167.814 117.608 168.370 1.00 325.58 ? 592 GLN R CG  1 
ATOM 6943 C CD  . GLN E 5 528 ? 169.078 116.916 168.846 1.00 325.75 ? 592 GLN R CD  1 
ATOM 6944 O OE1 . GLN E 5 528 ? 169.130 115.690 168.943 1.00 325.63 ? 592 GLN R OE1 1 
ATOM 6945 N NE2 . GLN E 5 528 ? 170.106 117.703 169.148 1.00 325.93 ? 592 GLN R NE2 1 
ATOM 6946 N N   . ALA E 5 529 ? 164.213 115.466 166.331 1.00 322.01 ? 593 ALA R N   1 
ATOM 6947 C CA  . ALA E 5 529 ? 163.471 114.797 165.261 1.00 321.42 ? 593 ALA R CA  1 
ATOM 6948 C C   . ALA E 5 529 ? 162.276 115.630 164.800 1.00 321.48 ? 593 ALA R C   1 
ATOM 6949 O O   . ALA E 5 529 ? 162.006 115.747 163.591 1.00 321.07 ? 593 ALA R O   1 
ATOM 6950 C CB  . ALA E 5 529 ? 163.011 113.417 165.728 1.00 321.52 ? 593 ALA R CB  1 
ATOM 6951 N N   . ALA E 5 530 ? 161.540 116.210 165.751 1.00 318.26 ? 594 ALA R N   1 
ATOM 6952 C CA  . ALA E 5 530 ? 160.428 117.080 165.389 1.00 317.55 ? 594 ALA R CA  1 
ATOM 6953 C C   . ALA E 5 530 ? 160.914 118.261 164.560 1.00 317.46 ? 594 ALA R C   1 
ATOM 6954 O O   . ALA E 5 530 ? 160.231 118.705 163.630 1.00 317.41 ? 594 ALA R O   1 
ATOM 6955 C CB  . ALA E 5 530 ? 159.707 117.561 166.647 1.00 317.43 ? 594 ALA R CB  1 
ATOM 6956 N N   . ALA E 5 531 ? 162.096 118.783 164.890 1.00 312.26 ? 595 ALA R N   1 
ATOM 6957 C CA  . ALA E 5 531 ? 162.697 119.838 164.085 1.00 311.88 ? 595 ALA R CA  1 
ATOM 6958 C C   . ALA E 5 531 ? 163.126 119.327 162.716 1.00 311.61 ? 595 ALA R C   1 
ATOM 6959 O O   . ALA E 5 531 ? 163.076 120.071 161.733 1.00 311.33 ? 595 ALA R O   1 
ATOM 6960 C CB  . ALA E 5 531 ? 163.890 120.440 164.823 1.00 311.76 ? 595 ALA R CB  1 
ATOM 6961 N N   . GLU E 5 532 ? 163.577 118.075 162.638 1.00 298.23 ? 596 GLU R N   1 
ATOM 6962 C CA  . GLU E 5 532 ? 163.933 117.498 161.347 1.00 297.60 ? 596 GLU R CA  1 
ATOM 6963 C C   . GLU E 5 532 ? 162.728 117.422 160.423 1.00 297.66 ? 596 GLU R C   1 
ATOM 6964 O O   . GLU E 5 532 ? 162.875 117.527 159.201 1.00 297.07 ? 596 GLU R O   1 
ATOM 6965 C CB  . GLU E 5 532 ? 164.542 116.111 161.539 1.00 297.33 ? 596 GLU R CB  1 
ATOM 6966 C CG  . GLU E 5 532 ? 165.936 116.120 162.140 1.00 297.27 ? 596 GLU R CG  1 
ATOM 6967 C CD  . GLU E 5 532 ? 166.526 114.729 162.240 1.00 297.49 ? 596 GLU R CD  1 
ATOM 6968 O OE1 . GLU E 5 532 ? 165.816 113.763 161.892 1.00 297.90 ? 596 GLU R OE1 1 
ATOM 6969 O OE2 . GLU E 5 532 ? 167.695 114.601 162.662 1.00 297.13 ? 596 GLU R OE2 1 
ATOM 6970 N N   . GLN E 5 533 ? 161.533 117.232 160.986 1.00 303.16 ? 597 GLN R N   1 
ATOM 6971 C CA  . GLN E 5 533 ? 160.321 117.300 160.164 1.00 303.26 ? 597 GLN R CA  1 
ATOM 6972 C C   . GLN E 5 533 ? 160.171 118.656 159.474 1.00 302.85 ? 597 GLN R C   1 
ATOM 6973 O O   . GLN E 5 533 ? 159.512 118.755 158.425 1.00 302.69 ? 597 GLN R O   1 
ATOM 6974 C CB  . GLN E 5 533 ? 159.081 117.023 161.008 1.00 303.32 ? 597 GLN R CB  1 
ATOM 6975 C CG  . GLN E 5 533 ? 159.024 115.640 161.617 1.00 303.23 ? 597 GLN R CG  1 
ATOM 6976 C CD  . GLN E 5 533 ? 157.816 115.463 162.514 1.00 303.05 ? 597 GLN R CD  1 
ATOM 6977 O OE1 . GLN E 5 533 ? 157.220 116.441 162.968 1.00 302.88 ? 597 GLN R OE1 1 
ATOM 6978 N NE2 . GLN E 5 533 ? 157.443 114.215 162.770 1.00 303.01 ? 597 GLN R NE2 1 
ATOM 6979 N N   . LEU E 5 534 ? 160.758 119.709 160.052 1.00 303.20 ? 598 LEU R N   1 
ATOM 6980 C CA  . LEU E 5 534 ? 160.700 121.026 159.430 1.00 303.62 ? 598 LEU R CA  1 
ATOM 6981 C C   . LEU E 5 534 ? 161.401 121.043 158.083 1.00 303.07 ? 598 LEU R C   1 
ATOM 6982 O O   . LEU E 5 534 ? 161.010 121.807 157.201 1.00 303.78 ? 598 LEU R O   1 
ATOM 6983 C CB  . LEU E 5 534 ? 161.315 122.076 160.349 1.00 303.64 ? 598 LEU R CB  1 
ATOM 6984 C CG  . LEU E 5 534 ? 160.636 122.234 161.703 1.00 303.46 ? 598 LEU R CG  1 
ATOM 6985 C CD1 . LEU E 5 534 ? 161.543 122.972 162.662 1.00 303.23 ? 598 LEU R CD1 1 
ATOM 6986 C CD2 . LEU E 5 534 ? 159.337 122.977 161.521 1.00 304.38 ? 598 LEU R CD2 1 
ATOM 6987 N N   . LYS E 5 535 ? 162.437 120.222 157.902 1.00 282.48 ? 599 LYS R N   1 
ATOM 6988 C CA  . LYS E 5 535 ? 163.087 120.158 156.596 1.00 282.25 ? 599 LYS R CA  1 
ATOM 6989 C C   . LYS E 5 535 ? 162.147 119.582 155.545 1.00 282.32 ? 599 LYS R C   1 
ATOM 6990 O O   . LYS E 5 535 ? 162.109 120.063 154.406 1.00 282.86 ? 599 LYS R O   1 
ATOM 6991 C CB  . LYS E 5 535 ? 164.373 119.339 156.685 1.00 281.77 ? 599 LYS R CB  1 
ATOM 6992 C CG  . LYS E 5 535 ? 165.451 119.979 157.544 1.00 282.02 ? 599 LYS R CG  1 
ATOM 6993 C CD  . LYS E 5 535 ? 166.789 119.272 157.392 1.00 282.24 ? 599 LYS R CD  1 
ATOM 6994 C CE  . LYS E 5 535 ? 167.869 119.968 158.205 1.00 282.82 ? 599 LYS R CE  1 
ATOM 6995 N NZ  . LYS E 5 535 ? 169.192 119.301 158.072 1.00 282.70 ? 599 LYS R NZ  1 
ATOM 6996 N N   . THR E 5 536 ? 161.377 118.556 155.913 1.00 272.37 ? 600 THR R N   1 
ATOM 6997 C CA  . THR E 5 536 ? 160.384 118.002 154.998 1.00 272.22 ? 600 THR R CA  1 
ATOM 6998 C C   . THR E 5 536 ? 159.325 119.039 154.649 1.00 272.28 ? 600 THR R C   1 
ATOM 6999 O O   . THR E 5 536 ? 158.973 119.217 153.477 1.00 271.81 ? 600 THR R O   1 
ATOM 7000 C CB  . THR E 5 536 ? 159.736 116.765 155.618 1.00 272.77 ? 600 THR R CB  1 
ATOM 7001 O OG1 . THR E 5 536 ? 160.745 115.787 155.897 1.00 272.96 ? 600 THR R OG1 1 
ATOM 7002 C CG2 . THR E 5 536 ? 158.699 116.171 154.671 1.00 272.67 ? 600 THR R CG2 1 
ATOM 7003 N N   . THR E 5 537 ? 158.813 119.744 155.661 1.00 279.05 ? 601 THR R N   1 
ATOM 7004 C CA  . THR E 5 537 ? 157.803 120.770 155.395 1.00 279.50 ? 601 THR R CA  1 
ATOM 7005 C C   . THR E 5 537 ? 158.368 121.891 154.523 1.00 278.90 ? 601 THR R C   1 
ATOM 7006 O O   . THR E 5 537 ? 157.690 122.391 153.612 1.00 278.41 ? 601 THR R O   1 
ATOM 7007 C CB  . THR E 5 537 ? 157.265 121.331 156.711 1.00 280.00 ? 601 THR R CB  1 
ATOM 7008 O OG1 . THR E 5 537 ? 156.734 120.261 157.502 1.00 280.19 ? 601 THR R OG1 1 
ATOM 7009 C CG2 . THR E 5 537 ? 156.164 122.346 156.450 1.00 279.61 ? 601 THR R CG2 1 
ATOM 7010 N N   . ARG E 5 538 ? 159.608 122.301 154.802 1.00 265.06 ? 602 ARG R N   1 
ATOM 7011 C CA  . ARG E 5 538 ? 160.277 123.325 154.012 1.00 264.09 ? 602 ARG R CA  1 
ATOM 7012 C C   . ARG E 5 538 ? 160.398 122.897 152.558 1.00 263.88 ? 602 ARG R C   1 
ATOM 7013 O O   . ARG E 5 538 ? 160.019 123.643 151.652 1.00 264.33 ? 602 ARG R O   1 
ATOM 7014 C CB  . ARG E 5 538 ? 161.656 123.610 154.608 1.00 264.45 ? 602 ARG R CB  1 
ATOM 7015 C CG  . ARG E 5 538 ? 162.516 124.544 153.785 1.00 264.04 ? 602 ARG R CG  1 
ATOM 7016 C CD  . ARG E 5 538 ? 163.964 124.477 154.238 1.00 263.75 ? 602 ARG R CD  1 
ATOM 7017 N NE  . ARG E 5 538 ? 164.507 123.135 154.066 1.00 263.72 ? 602 ARG R NE  1 
ATOM 7018 C CZ  . ARG E 5 538 ? 165.719 122.756 154.449 1.00 264.32 ? 602 ARG R CZ  1 
ATOM 7019 N NH1 . ARG E 5 538 ? 166.551 123.595 155.044 1.00 264.44 ? 602 ARG R NH1 1 
ATOM 7020 N NH2 . ARG E 5 538 ? 166.104 121.502 154.230 1.00 264.55 ? 602 ARG R NH2 1 
ATOM 7021 N N   . ASN E 5 539 ? 160.886 121.680 152.318 1.00 257.46 ? 603 ASN R N   1 
ATOM 7022 C CA  . ASN E 5 539 ? 161.003 121.198 150.947 1.00 257.59 ? 603 ASN R CA  1 
ATOM 7023 C C   . ASN E 5 539 ? 159.639 121.116 150.271 1.00 257.74 ? 603 ASN R C   1 
ATOM 7024 O O   . ASN E 5 539 ? 159.521 121.366 149.067 1.00 257.49 ? 603 ASN R O   1 
ATOM 7025 C CB  . ASN E 5 539 ? 161.706 119.839 150.923 1.00 256.69 ? 603 ASN R CB  1 
ATOM 7026 C CG  . ASN E 5 539 ? 163.187 119.940 151.259 1.00 257.07 ? 603 ASN R CG  1 
ATOM 7027 O OD1 . ASN E 5 539 ? 163.774 121.022 151.217 1.00 257.39 ? 603 ASN R OD1 1 
ATOM 7028 N ND2 . ASN E 5 539 ? 163.799 118.806 151.582 1.00 257.31 ? 603 ASN R ND2 1 
ATOM 7029 N N   . ALA E 5 540 ? 158.594 120.769 151.028 1.00 253.55 ? 604 ALA R N   1 
ATOM 7030 C CA  . ALA E 5 540 ? 157.261 120.682 150.436 1.00 252.99 ? 604 ALA R CA  1 
ATOM 7031 C C   . ALA E 5 540 ? 156.729 122.047 150.006 1.00 252.92 ? 604 ALA R C   1 
ATOM 7032 O O   . ALA E 5 540 ? 156.114 122.163 148.941 1.00 252.58 ? 604 ALA R O   1 
ATOM 7033 C CB  . ALA E 5 540 ? 156.291 120.019 151.411 1.00 252.61 ? 604 ALA R CB  1 
ATOM 7034 N N   . TYR E 5 541 ? 156.940 123.090 150.813 1.00 243.43 ? 605 TYR R N   1 
ATOM 7035 C CA  . TYR E 5 541 ? 156.246 124.358 150.583 1.00 242.78 ? 605 TYR R CA  1 
ATOM 7036 C C   . TYR E 5 541 ? 157.169 125.513 150.223 1.00 241.98 ? 605 TYR R C   1 
ATOM 7037 O O   . TYR E 5 541 ? 156.915 126.235 149.241 1.00 240.89 ? 605 TYR R O   1 
ATOM 7038 C CB  . TYR E 5 541 ? 155.426 124.729 151.830 1.00 242.92 ? 605 TYR R CB  1 
ATOM 7039 C CG  . TYR E 5 541 ? 154.306 123.769 152.166 1.00 242.97 ? 605 TYR R CG  1 
ATOM 7040 C CD1 . TYR E 5 541 ? 153.063 123.889 151.562 1.00 242.81 ? 605 TYR R CD1 1 
ATOM 7041 C CD2 . TYR E 5 541 ? 154.486 122.757 153.101 1.00 243.29 ? 605 TYR R CD2 1 
ATOM 7042 C CE1 . TYR E 5 541 ? 152.032 123.023 151.870 1.00 242.16 ? 605 TYR R CE1 1 
ATOM 7043 C CE2 . TYR E 5 541 ? 153.459 121.884 153.417 1.00 243.63 ? 605 TYR R CE2 1 
ATOM 7044 C CZ  . TYR E 5 541 ? 152.233 122.023 152.797 1.00 242.69 ? 605 TYR R CZ  1 
ATOM 7045 O OH  . TYR E 5 541 ? 151.203 121.163 153.100 1.00 242.35 ? 605 TYR R OH  1 
ATOM 7046 N N   . ILE E 5 542 ? 158.220 125.729 151.015 1.00 236.55 ? 606 ILE R N   1 
ATOM 7047 C CA  . ILE E 5 542 ? 159.075 126.897 150.855 1.00 236.59 ? 606 ILE R CA  1 
ATOM 7048 C C   . ILE E 5 542 ? 159.764 126.884 149.500 1.00 235.51 ? 606 ILE R C   1 
ATOM 7049 O O   . ILE E 5 542 ? 160.007 127.942 148.913 1.00 236.00 ? 606 ILE R O   1 
ATOM 7050 C CB  . ILE E 5 542 ? 160.086 126.953 152.020 1.00 236.18 ? 606 ILE R CB  1 
ATOM 7051 C CG1 . ILE E 5 542 ? 159.351 127.248 153.333 1.00 234.95 ? 606 ILE R CG1 1 
ATOM 7052 C CG2 . ILE E 5 542 ? 161.182 127.972 151.749 1.00 235.02 ? 606 ILE R CG2 1 
ATOM 7053 C CD1 . ILE E 5 542 ? 160.250 127.336 154.542 1.00 234.60 ? 606 ILE R CD1 1 
ATOM 7054 N N   . GLN E 5 543 ? 160.101 125.702 148.983 1.00 213.79 ? 607 GLN R N   1 
ATOM 7055 C CA  . GLN E 5 543 ? 160.690 125.625 147.649 1.00 212.64 ? 607 GLN R CA  1 
ATOM 7056 C C   . GLN E 5 543 ? 159.719 126.106 146.578 1.00 213.45 ? 607 GLN R C   1 
ATOM 7057 O O   . GLN E 5 543 ? 160.110 126.833 145.654 1.00 214.29 ? 607 GLN R O   1 
ATOM 7058 C CB  . GLN E 5 543 ? 161.143 124.201 147.355 1.00 211.47 ? 607 GLN R CB  1 
ATOM 7059 C CG  . GLN E 5 543 ? 162.308 123.758 148.206 1.00 212.81 ? 607 GLN R CG  1 
ATOM 7060 C CD  . GLN E 5 543 ? 163.507 124.670 148.058 1.00 211.29 ? 607 GLN R CD  1 
ATOM 7061 O OE1 . GLN E 5 543 ? 163.812 125.145 146.962 1.00 211.08 ? 607 GLN R OE1 1 
ATOM 7062 N NE2 . GLN E 5 543 ? 164.194 124.924 149.164 1.00 211.19 ? 607 GLN R NE2 1 
ATOM 7063 N N   . LYS E 5 544 ? 158.445 125.723 146.690 1.00 215.63 ? 608 LYS R N   1 
ATOM 7064 C CA  . LYS E 5 544 ? 157.448 126.226 145.753 1.00 215.67 ? 608 LYS R CA  1 
ATOM 7065 C C   . LYS E 5 544 ? 157.336 127.738 145.851 1.00 215.87 ? 608 LYS R C   1 
ATOM 7066 O O   . LYS E 5 544 ? 157.211 128.430 144.835 1.00 215.44 ? 608 LYS R O   1 
ATOM 7067 C CB  . LYS E 5 544 ? 156.092 125.578 146.019 1.00 215.03 ? 608 LYS R CB  1 
ATOM 7068 C CG  . LYS E 5 544 ? 156.067 124.070 145.873 1.00 215.55 ? 608 LYS R CG  1 
ATOM 7069 C CD  . LYS E 5 544 ? 154.684 123.520 146.190 1.00 214.90 ? 608 LYS R CD  1 
ATOM 7070 C CE  . LYS E 5 544 ? 154.639 122.007 146.044 1.00 214.27 ? 608 LYS R CE  1 
ATOM 7071 N NZ  . LYS E 5 544 ? 153.324 121.436 146.454 1.00 215.08 ? 608 LYS R NZ  1 
ATOM 7072 N N   . TYR E 5 545 ? 157.379 128.269 147.073 1.00 229.00 ? 609 TYR R N   1 
ATOM 7073 C CA  . TYR E 5 545 ? 157.271 129.718 147.227 1.00 229.15 ? 609 TYR R CA  1 
ATOM 7074 C C   . TYR E 5 545 ? 158.518 130.424 146.702 1.00 228.21 ? 609 TYR R C   1 
ATOM 7075 O O   . TYR E 5 545 ? 158.428 131.541 146.178 1.00 228.62 ? 609 TYR R O   1 
ATOM 7076 C CB  . TYR E 5 545 ? 156.997 130.063 148.691 1.00 230.91 ? 609 TYR R CB  1 
ATOM 7077 C CG  . TYR E 5 545 ? 155.857 129.250 149.259 1.00 231.37 ? 609 TYR R CG  1 
ATOM 7078 C CD1 . TYR E 5 545 ? 154.787 128.869 148.455 1.00 231.13 ? 609 TYR R CD1 1 
ATOM 7079 C CD2 . TYR E 5 545 ? 155.863 128.836 150.582 1.00 229.61 ? 609 TYR R CD2 1 
ATOM 7080 C CE1 . TYR E 5 545 ? 153.754 128.112 148.955 1.00 231.16 ? 609 TYR R CE1 1 
ATOM 7081 C CE2 . TYR E 5 545 ? 154.828 128.082 151.093 1.00 229.50 ? 609 TYR R CE2 1 
ATOM 7082 C CZ  . TYR E 5 545 ? 153.779 127.721 150.275 1.00 231.04 ? 609 TYR R CZ  1 
ATOM 7083 O OH  . TYR E 5 545 ? 152.750 126.965 150.781 1.00 230.72 ? 609 TYR R OH  1 
ATOM 7084 N N   . LEU E 5 546 ? 159.681 129.783 146.831 1.00 195.05 ? 610 LEU R N   1 
ATOM 7085 C CA  . LEU E 5 546 ? 160.911 130.285 146.230 1.00 193.92 ? 610 LEU R CA  1 
ATOM 7086 C C   . LEU E 5 546 ? 160.819 130.311 144.714 1.00 191.79 ? 610 LEU R C   1 
ATOM 7087 O O   . LEU E 5 546 ? 161.425 131.175 144.069 1.00 192.18 ? 610 LEU R O   1 
ATOM 7088 C CB  . LEU E 5 546 ? 162.094 129.418 146.660 1.00 195.18 ? 610 LEU R CB  1 
ATOM 7089 C CG  . LEU E 5 546 ? 162.736 129.716 148.013 1.00 192.98 ? 610 LEU R CG  1 
ATOM 7090 C CD1 . LEU E 5 546 ? 163.689 128.604 148.423 1.00 191.73 ? 610 LEU R CD1 1 
ATOM 7091 C CD2 . LEU E 5 546 ? 163.464 131.043 147.941 1.00 192.77 ? 610 LEU R CD2 1 
ATOM 7092 N N   . ARG E 5 547 ? 160.078 129.368 144.127 1.00 178.20 ? 611 ARG R N   1 
ATOM 7093 C CA  . ARG E 5 547 ? 159.904 129.358 142.679 1.00 176.45 ? 611 ARG R CA  1 
ATOM 7094 C C   . ARG E 5 547 ? 159.259 130.638 142.164 1.00 176.26 ? 611 ARG R C   1 
ATOM 7095 O O   . ARG E 5 547 ? 159.380 130.943 140.973 1.00 175.94 ? 611 ARG R O   1 
ATOM 7096 C CB  . ARG E 5 547 ? 159.059 128.162 142.247 1.00 179.24 ? 611 ARG R CB  1 
ATOM 7097 C CG  . ARG E 5 547 ? 159.701 126.810 142.467 1.00 181.11 ? 611 ARG R CG  1 
ATOM 7098 C CD  . ARG E 5 547 ? 158.727 125.704 142.100 1.00 181.55 ? 611 ARG R CD  1 
ATOM 7099 N NE  . ARG E 5 547 ? 159.319 124.380 142.238 1.00 181.46 ? 611 ARG R NE  1 
ATOM 7100 C CZ  . ARG E 5 547 ? 158.660 123.244 142.055 1.00 182.12 ? 611 ARG R CZ  1 
ATOM 7101 N NH1 . ARG E 5 547 ? 157.376 123.233 141.734 1.00 180.62 ? 611 ARG R NH1 1 
ATOM 7102 N NH2 . ARG E 5 547 ? 159.304 122.090 142.201 1.00 181.50 ? 611 ARG R NH2 1 
ATOM 7103 N N   . ALA E 5 548 ? 158.566 131.387 143.026 1.00 160.34 ? 612 ALA R N   1 
ATOM 7104 C CA  . ALA E 5 548 ? 157.987 132.656 142.602 1.00 160.37 ? 612 ALA R CA  1 
ATOM 7105 C C   . ALA E 5 548 ? 159.055 133.644 142.146 1.00 159.50 ? 612 ALA R C   1 
ATOM 7106 O O   . ALA E 5 548 ? 158.742 134.583 141.406 1.00 153.90 ? 612 ALA R O   1 
ATOM 7107 C CB  . ALA E 5 548 ? 157.153 133.259 143.736 1.00 160.31 ? 612 ALA R CB  1 
ATOM 7108 N N   . ARG E 5 549 ? 160.308 133.450 142.566 1.00 152.45 ? 613 ARG R N   1 
ATOM 7109 C CA  . ARG E 5 549 ? 161.387 134.334 142.138 1.00 147.86 ? 613 ARG R CA  1 
ATOM 7110 C C   . ARG E 5 549 ? 161.628 134.272 140.638 1.00 144.40 ? 613 ARG R C   1 
ATOM 7111 O O   . ARG E 5 549 ? 162.182 135.221 140.072 1.00 144.07 ? 613 ARG R O   1 
ATOM 7112 C CB  . ARG E 5 549 ? 162.682 133.993 142.875 1.00 146.29 ? 613 ARG R CB  1 
ATOM 7113 C CG  . ARG E 5 549 ? 162.632 134.220 144.370 1.00 150.10 ? 613 ARG R CG  1 
ATOM 7114 C CD  . ARG E 5 549 ? 163.922 133.762 145.017 1.00 152.03 ? 613 ARG R CD  1 
ATOM 7115 N NE  . ARG E 5 549 ? 164.226 132.374 144.690 1.00 156.39 ? 613 ARG R NE  1 
ATOM 7116 C CZ  . ARG E 5 549 ? 165.305 131.725 145.105 1.00 155.29 ? 613 ARG R CZ  1 
ATOM 7117 N NH1 . ARG E 5 549 ? 166.210 132.309 145.873 1.00 152.84 ? 613 ARG R NH1 1 
ATOM 7118 N NH2 . ARG E 5 549 ? 165.480 130.457 144.741 1.00 152.32 ? 613 ARG R NH2 1 
ATOM 7119 N N   . SER E 5 550 ? 161.232 133.182 139.981 1.00 127.71 ? 614 SER R N   1 
ATOM 7120 C CA  . SER E 5 550 ? 161.341 133.094 138.532 1.00 126.94 ? 614 SER R CA  1 
ATOM 7121 C C   . SER E 5 550 ? 160.228 133.845 137.818 1.00 128.59 ? 614 SER R C   1 
ATOM 7122 O O   . SER E 5 550 ? 160.293 133.998 136.594 1.00 137.60 ? 614 SER R O   1 
ATOM 7123 C CB  . SER E 5 550 ? 161.337 131.631 138.085 1.00 132.10 ? 614 SER R CB  1 
ATOM 7124 O OG  . SER E 5 550 ? 160.059 131.048 138.268 1.00 133.24 ? 614 SER R OG  1 
ATOM 7125 N N   . THR E 5 551 ? 159.214 134.310 138.547 1.00 106.46 ? 615 THR R N   1 
ATOM 7126 C CA  . THR E 5 551 ? 158.122 135.083 137.969 1.00 109.36 ? 615 THR R CA  1 
ATOM 7127 C C   . THR E 5 551 ? 158.309 136.582 138.169 1.00 107.66 ? 615 THR R C   1 
ATOM 7128 O O   . THR E 5 551 ? 158.141 137.345 137.217 1.00 113.87 ? 615 THR R O   1 
ATOM 7129 C CB  . THR E 5 551 ? 156.779 134.641 138.566 1.00 112.93 ? 615 THR R CB  1 
ATOM 7130 O OG1 . THR E 5 551 ? 156.573 133.246 138.314 1.00 115.60 ? 615 THR R OG1 1 
ATOM 7131 C CG2 . THR E 5 551 ? 155.641 135.427 137.940 1.00 109.85 ? 615 THR R CG2 1 
ATOM 7132 N N   . LEU E 5 552 ? 158.662 136.998 139.389 1.00 91.82  ? 616 LEU R N   1 
ATOM 7133 C CA  . LEU E 5 552 ? 158.907 138.396 139.800 1.00 96.33  ? 616 LEU R CA  1 
ATOM 7134 C C   . LEU E 5 552 ? 158.812 139.471 138.713 1.00 90.30  ? 616 LEU R C   1 
ATOM 7135 O O   . LEU E 5 552 ? 159.678 139.574 137.844 1.00 87.25  ? 616 LEU R O   1 
ATOM 7136 C CB  . LEU E 5 552 ? 160.288 138.491 140.461 1.00 95.56  ? 616 LEU R CB  1 
ATOM 7137 C CG  . LEU E 5 552 ? 160.839 139.894 140.744 1.00 92.86  ? 616 LEU R CG  1 
ATOM 7138 C CD1 . LEU E 5 552 ? 159.974 140.632 141.751 1.00 95.92  ? 616 LEU R CD1 1 
ATOM 7139 C CD2 . LEU E 5 552 ? 162.284 139.833 141.219 1.00 98.48  ? 616 LEU R CD2 1 
# 
