data_9H5J
# 
_entry.id   9H5J 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9H5J         pdb_00009h5j 10.2210/pdb9h5j/pdb 
WWPDB D_1292142681 ?            ?                   
EMDB  EMD-51886    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-12-04 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9H5J 
_pdbx_database_status.recvd_initial_deposition_date   2024-10-22 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'PAD12 0N3R tau PHF seeded by AD' 
_pdbx_database_related.db_id          EMD-51886 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 scheres@mrc-lmb.cam.ac.uk Sjors  Scheres H.W 'principal investigator/group leader' 0000-0002-0462-6540 
3 mg@mrc-lmb.cam.ac.uk      Michel Goedert ?   'principal investigator/group leader' 0000-0002-5214-7886 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lovestam, S.'    1 ? 
'Scheres, S.H.W.' 2 ? 
'Goedert, M.'     3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Twelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lovestam, S.'    1 ? 
primary 'Scheres, S.H.W.' 2 ? 
primary 'Goedert, M.'     3 ? 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           'Isoform Fetal-tau of Microtubule-associated protein tau' 
_entity.formula_weight             37073.078 
_entity.pdbx_number_of_molecules   6 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Neurofibrillary tangle protein,Paired helical filament-tau,PHF-tau' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSD
DKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKDPPSSGEPPKSGDRSGYSSPGDPGDPGSRSRDPDLPDP
PTREPKKVAVVRDPPKDPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIH
HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKDPVVDGDDDPRHLS
NVSSTGSIDMVDSPQLATLADEVSASLAKQGL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSD
DKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKDPPSSGEPPKSGDRSGYSSPGDPGDPGSRSRDPDLPDP
PTREPKKVAVVRDPPKDPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIH
HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKDPVVDGDDDPRHLS
NVSSTGSIDMVDSPQLATLADEVSASLAKQGL
;
_entity_poly.pdbx_strand_id                 A,B,C,D,E,F 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   GLU n 
1 4   PRO n 
1 5   ARG n 
1 6   GLN n 
1 7   GLU n 
1 8   PHE n 
1 9   GLU n 
1 10  VAL n 
1 11  MET n 
1 12  GLU n 
1 13  ASP n 
1 14  HIS n 
1 15  ALA n 
1 16  GLY n 
1 17  THR n 
1 18  TYR n 
1 19  GLY n 
1 20  LEU n 
1 21  GLY n 
1 22  ASP n 
1 23  ARG n 
1 24  LYS n 
1 25  ASP n 
1 26  GLN n 
1 27  GLY n 
1 28  GLY n 
1 29  TYR n 
1 30  THR n 
1 31  MET n 
1 32  HIS n 
1 33  GLN n 
1 34  ASP n 
1 35  GLN n 
1 36  GLU n 
1 37  GLY n 
1 38  ASP n 
1 39  THR n 
1 40  ASP n 
1 41  ALA n 
1 42  GLY n 
1 43  LEU n 
1 44  LYS n 
1 45  ALA n 
1 46  GLU n 
1 47  GLU n 
1 48  ALA n 
1 49  GLY n 
1 50  ILE n 
1 51  GLY n 
1 52  ASP n 
1 53  THR n 
1 54  PRO n 
1 55  SER n 
1 56  LEU n 
1 57  GLU n 
1 58  ASP n 
1 59  GLU n 
1 60  ALA n 
1 61  ALA n 
1 62  GLY n 
1 63  HIS n 
1 64  VAL n 
1 65  THR n 
1 66  GLN n 
1 67  ALA n 
1 68  ARG n 
1 69  MET n 
1 70  VAL n 
1 71  SER n 
1 72  LYS n 
1 73  SER n 
1 74  LYS n 
1 75  ASP n 
1 76  GLY n 
1 77  THR n 
1 78  GLY n 
1 79  SER n 
1 80  ASP n 
1 81  ASP n 
1 82  LYS n 
1 83  LYS n 
1 84  ALA n 
1 85  LYS n 
1 86  GLY n 
1 87  ALA n 
1 88  ASP n 
1 89  GLY n 
1 90  LYS n 
1 91  THR n 
1 92  LYS n 
1 93  ILE n 
1 94  ALA n 
1 95  THR n 
1 96  PRO n 
1 97  ARG n 
1 98  GLY n 
1 99  ALA n 
1 100 ALA n 
1 101 PRO n 
1 102 PRO n 
1 103 GLY n 
1 104 GLN n 
1 105 LYS n 
1 106 GLY n 
1 107 GLN n 
1 108 ALA n 
1 109 ASN n 
1 110 ALA n 
1 111 THR n 
1 112 ARG n 
1 113 ILE n 
1 114 PRO n 
1 115 ALA n 
1 116 LYS n 
1 117 THR n 
1 118 PRO n 
1 119 PRO n 
1 120 ALA n 
1 121 PRO n 
1 122 LYS n 
1 123 ASP n 
1 124 PRO n 
1 125 PRO n 
1 126 SER n 
1 127 SER n 
1 128 GLY n 
1 129 GLU n 
1 130 PRO n 
1 131 PRO n 
1 132 LYS n 
1 133 SER n 
1 134 GLY n 
1 135 ASP n 
1 136 ARG n 
1 137 SER n 
1 138 GLY n 
1 139 TYR n 
1 140 SER n 
1 141 SER n 
1 142 PRO n 
1 143 GLY n 
1 144 ASP n 
1 145 PRO n 
1 146 GLY n 
1 147 ASP n 
1 148 PRO n 
1 149 GLY n 
1 150 SER n 
1 151 ARG n 
1 152 SER n 
1 153 ARG n 
1 154 ASP n 
1 155 PRO n 
1 156 ASP n 
1 157 LEU n 
1 158 PRO n 
1 159 ASP n 
1 160 PRO n 
1 161 PRO n 
1 162 THR n 
1 163 ARG n 
1 164 GLU n 
1 165 PRO n 
1 166 LYS n 
1 167 LYS n 
1 168 VAL n 
1 169 ALA n 
1 170 VAL n 
1 171 VAL n 
1 172 ARG n 
1 173 ASP n 
1 174 PRO n 
1 175 PRO n 
1 176 LYS n 
1 177 ASP n 
1 178 PRO n 
1 179 SER n 
1 180 SER n 
1 181 ALA n 
1 182 LYS n 
1 183 SER n 
1 184 ARG n 
1 185 LEU n 
1 186 GLN n 
1 187 THR n 
1 188 ALA n 
1 189 PRO n 
1 190 VAL n 
1 191 PRO n 
1 192 MET n 
1 193 PRO n 
1 194 ASP n 
1 195 LEU n 
1 196 LYS n 
1 197 ASN n 
1 198 VAL n 
1 199 LYS n 
1 200 SER n 
1 201 LYS n 
1 202 ILE n 
1 203 GLY n 
1 204 SER n 
1 205 THR n 
1 206 GLU n 
1 207 ASN n 
1 208 LEU n 
1 209 LYS n 
1 210 HIS n 
1 211 GLN n 
1 212 PRO n 
1 213 GLY n 
1 214 GLY n 
1 215 GLY n 
1 216 LYS n 
1 217 VAL n 
1 218 GLN n 
1 219 ILE n 
1 220 VAL n 
1 221 TYR n 
1 222 LYS n 
1 223 PRO n 
1 224 VAL n 
1 225 ASP n 
1 226 LEU n 
1 227 SER n 
1 228 LYS n 
1 229 VAL n 
1 230 THR n 
1 231 SER n 
1 232 LYS n 
1 233 CYS n 
1 234 GLY n 
1 235 SER n 
1 236 LEU n 
1 237 GLY n 
1 238 ASN n 
1 239 ILE n 
1 240 HIS n 
1 241 HIS n 
1 242 LYS n 
1 243 PRO n 
1 244 GLY n 
1 245 GLY n 
1 246 GLY n 
1 247 GLN n 
1 248 VAL n 
1 249 GLU n 
1 250 VAL n 
1 251 LYS n 
1 252 SER n 
1 253 GLU n 
1 254 LYS n 
1 255 LEU n 
1 256 ASP n 
1 257 PHE n 
1 258 LYS n 
1 259 ASP n 
1 260 ARG n 
1 261 VAL n 
1 262 GLN n 
1 263 SER n 
1 264 LYS n 
1 265 ILE n 
1 266 GLY n 
1 267 SER n 
1 268 LEU n 
1 269 ASP n 
1 270 ASN n 
1 271 ILE n 
1 272 THR n 
1 273 HIS n 
1 274 VAL n 
1 275 PRO n 
1 276 GLY n 
1 277 GLY n 
1 278 GLY n 
1 279 ASN n 
1 280 LYS n 
1 281 LYS n 
1 282 ILE n 
1 283 GLU n 
1 284 THR n 
1 285 HIS n 
1 286 LYS n 
1 287 LEU n 
1 288 THR n 
1 289 PHE n 
1 290 ARG n 
1 291 GLU n 
1 292 ASN n 
1 293 ALA n 
1 294 LYS n 
1 295 ALA n 
1 296 LYS n 
1 297 THR n 
1 298 ASP n 
1 299 HIS n 
1 300 GLY n 
1 301 ALA n 
1 302 GLU n 
1 303 ILE n 
1 304 VAL n 
1 305 TYR n 
1 306 LYS n 
1 307 ASP n 
1 308 PRO n 
1 309 VAL n 
1 310 VAL n 
1 311 ASP n 
1 312 GLY n 
1 313 ASP n 
1 314 ASP n 
1 315 ASP n 
1 316 PRO n 
1 317 ARG n 
1 318 HIS n 
1 319 LEU n 
1 320 SER n 
1 321 ASN n 
1 322 VAL n 
1 323 SER n 
1 324 SER n 
1 325 THR n 
1 326 GLY n 
1 327 SER n 
1 328 ILE n 
1 329 ASP n 
1 330 MET n 
1 331 VAL n 
1 332 ASP n 
1 333 SER n 
1 334 PRO n 
1 335 GLN n 
1 336 LEU n 
1 337 ALA n 
1 338 THR n 
1 339 LEU n 
1 340 ALA n 
1 341 ASP n 
1 342 GLU n 
1 343 VAL n 
1 344 SER n 
1 345 ALA n 
1 346 SER n 
1 347 LEU n 
1 348 ALA n 
1 349 LYS n 
1 350 GLN n 
1 351 GLY n 
1 352 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   352 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'MAPT, MAPTL, MTBT1, TAU' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   90  ?   ?   ?   A . n 
A 1 2   ALA 2   91  ?   ?   ?   A . n 
A 1 3   GLU 3   92  ?   ?   ?   A . n 
A 1 4   PRO 4   93  ?   ?   ?   A . n 
A 1 5   ARG 5   94  ?   ?   ?   A . n 
A 1 6   GLN 6   95  ?   ?   ?   A . n 
A 1 7   GLU 7   96  ?   ?   ?   A . n 
A 1 8   PHE 8   97  ?   ?   ?   A . n 
A 1 9   GLU 9   98  ?   ?   ?   A . n 
A 1 10  VAL 10  99  ?   ?   ?   A . n 
A 1 11  MET 11  100 ?   ?   ?   A . n 
A 1 12  GLU 12  101 ?   ?   ?   A . n 
A 1 13  ASP 13  102 ?   ?   ?   A . n 
A 1 14  HIS 14  103 ?   ?   ?   A . n 
A 1 15  ALA 15  104 ?   ?   ?   A . n 
A 1 16  GLY 16  105 ?   ?   ?   A . n 
A 1 17  THR 17  106 ?   ?   ?   A . n 
A 1 18  TYR 18  107 ?   ?   ?   A . n 
A 1 19  GLY 19  108 ?   ?   ?   A . n 
A 1 20  LEU 20  109 ?   ?   ?   A . n 
A 1 21  GLY 21  110 ?   ?   ?   A . n 
A 1 22  ASP 22  111 ?   ?   ?   A . n 
A 1 23  ARG 23  112 ?   ?   ?   A . n 
A 1 24  LYS 24  113 ?   ?   ?   A . n 
A 1 25  ASP 25  114 ?   ?   ?   A . n 
A 1 26  GLN 26  115 ?   ?   ?   A . n 
A 1 27  GLY 27  116 ?   ?   ?   A . n 
A 1 28  GLY 28  117 ?   ?   ?   A . n 
A 1 29  TYR 29  118 ?   ?   ?   A . n 
A 1 30  THR 30  119 ?   ?   ?   A . n 
A 1 31  MET 31  120 ?   ?   ?   A . n 
A 1 32  HIS 32  121 ?   ?   ?   A . n 
A 1 33  GLN 33  122 ?   ?   ?   A . n 
A 1 34  ASP 34  123 ?   ?   ?   A . n 
A 1 35  GLN 35  124 ?   ?   ?   A . n 
A 1 36  GLU 36  125 ?   ?   ?   A . n 
A 1 37  GLY 37  126 ?   ?   ?   A . n 
A 1 38  ASP 38  127 ?   ?   ?   A . n 
A 1 39  THR 39  128 ?   ?   ?   A . n 
A 1 40  ASP 40  129 ?   ?   ?   A . n 
A 1 41  ALA 41  130 ?   ?   ?   A . n 
A 1 42  GLY 42  131 ?   ?   ?   A . n 
A 1 43  LEU 43  132 ?   ?   ?   A . n 
A 1 44  LYS 44  133 ?   ?   ?   A . n 
A 1 45  ALA 45  134 ?   ?   ?   A . n 
A 1 46  GLU 46  135 ?   ?   ?   A . n 
A 1 47  GLU 47  136 ?   ?   ?   A . n 
A 1 48  ALA 48  137 ?   ?   ?   A . n 
A 1 49  GLY 49  138 ?   ?   ?   A . n 
A 1 50  ILE 50  139 ?   ?   ?   A . n 
A 1 51  GLY 51  140 ?   ?   ?   A . n 
A 1 52  ASP 52  141 ?   ?   ?   A . n 
A 1 53  THR 53  142 ?   ?   ?   A . n 
A 1 54  PRO 54  143 ?   ?   ?   A . n 
A 1 55  SER 55  144 ?   ?   ?   A . n 
A 1 56  LEU 56  145 ?   ?   ?   A . n 
A 1 57  GLU 57  146 ?   ?   ?   A . n 
A 1 58  ASP 58  147 ?   ?   ?   A . n 
A 1 59  GLU 59  148 ?   ?   ?   A . n 
A 1 60  ALA 60  149 ?   ?   ?   A . n 
A 1 61  ALA 61  150 ?   ?   ?   A . n 
A 1 62  GLY 62  151 ?   ?   ?   A . n 
A 1 63  HIS 63  152 ?   ?   ?   A . n 
A 1 64  VAL 64  153 ?   ?   ?   A . n 
A 1 65  THR 65  154 ?   ?   ?   A . n 
A 1 66  GLN 66  155 ?   ?   ?   A . n 
A 1 67  ALA 67  156 ?   ?   ?   A . n 
A 1 68  ARG 68  157 ?   ?   ?   A . n 
A 1 69  MET 69  158 ?   ?   ?   A . n 
A 1 70  VAL 70  159 ?   ?   ?   A . n 
A 1 71  SER 71  160 ?   ?   ?   A . n 
A 1 72  LYS 72  161 ?   ?   ?   A . n 
A 1 73  SER 73  162 ?   ?   ?   A . n 
A 1 74  LYS 74  163 ?   ?   ?   A . n 
A 1 75  ASP 75  164 ?   ?   ?   A . n 
A 1 76  GLY 76  165 ?   ?   ?   A . n 
A 1 77  THR 77  166 ?   ?   ?   A . n 
A 1 78  GLY 78  167 ?   ?   ?   A . n 
A 1 79  SER 79  168 ?   ?   ?   A . n 
A 1 80  ASP 80  169 ?   ?   ?   A . n 
A 1 81  ASP 81  170 ?   ?   ?   A . n 
A 1 82  LYS 82  171 ?   ?   ?   A . n 
A 1 83  LYS 83  172 ?   ?   ?   A . n 
A 1 84  ALA 84  173 ?   ?   ?   A . n 
A 1 85  LYS 85  174 ?   ?   ?   A . n 
A 1 86  GLY 86  175 ?   ?   ?   A . n 
A 1 87  ALA 87  176 ?   ?   ?   A . n 
A 1 88  ASP 88  177 ?   ?   ?   A . n 
A 1 89  GLY 89  178 ?   ?   ?   A . n 
A 1 90  LYS 90  179 ?   ?   ?   A . n 
A 1 91  THR 91  180 ?   ?   ?   A . n 
A 1 92  LYS 92  181 ?   ?   ?   A . n 
A 1 93  ILE 93  182 ?   ?   ?   A . n 
A 1 94  ALA 94  183 ?   ?   ?   A . n 
A 1 95  THR 95  184 ?   ?   ?   A . n 
A 1 96  PRO 96  185 ?   ?   ?   A . n 
A 1 97  ARG 97  186 ?   ?   ?   A . n 
A 1 98  GLY 98  187 ?   ?   ?   A . n 
A 1 99  ALA 99  188 ?   ?   ?   A . n 
A 1 100 ALA 100 189 ?   ?   ?   A . n 
A 1 101 PRO 101 190 ?   ?   ?   A . n 
A 1 102 PRO 102 191 ?   ?   ?   A . n 
A 1 103 GLY 103 192 ?   ?   ?   A . n 
A 1 104 GLN 104 193 ?   ?   ?   A . n 
A 1 105 LYS 105 194 ?   ?   ?   A . n 
A 1 106 GLY 106 195 ?   ?   ?   A . n 
A 1 107 GLN 107 196 ?   ?   ?   A . n 
A 1 108 ALA 108 197 ?   ?   ?   A . n 
A 1 109 ASN 109 198 ?   ?   ?   A . n 
A 1 110 ALA 110 199 ?   ?   ?   A . n 
A 1 111 THR 111 200 ?   ?   ?   A . n 
A 1 112 ARG 112 201 ?   ?   ?   A . n 
A 1 113 ILE 113 202 ?   ?   ?   A . n 
A 1 114 PRO 114 203 ?   ?   ?   A . n 
A 1 115 ALA 115 204 ?   ?   ?   A . n 
A 1 116 LYS 116 205 ?   ?   ?   A . n 
A 1 117 THR 117 206 ?   ?   ?   A . n 
A 1 118 PRO 118 207 ?   ?   ?   A . n 
A 1 119 PRO 119 208 ?   ?   ?   A . n 
A 1 120 ALA 120 209 ?   ?   ?   A . n 
A 1 121 PRO 121 210 ?   ?   ?   A . n 
A 1 122 LYS 122 211 ?   ?   ?   A . n 
A 1 123 ASP 123 212 ?   ?   ?   A . n 
A 1 124 PRO 124 213 ?   ?   ?   A . n 
A 1 125 PRO 125 214 ?   ?   ?   A . n 
A 1 126 SER 126 215 ?   ?   ?   A . n 
A 1 127 SER 127 216 ?   ?   ?   A . n 
A 1 128 GLY 128 217 ?   ?   ?   A . n 
A 1 129 GLU 129 218 ?   ?   ?   A . n 
A 1 130 PRO 130 219 ?   ?   ?   A . n 
A 1 131 PRO 131 220 ?   ?   ?   A . n 
A 1 132 LYS 132 221 ?   ?   ?   A . n 
A 1 133 SER 133 222 ?   ?   ?   A . n 
A 1 134 GLY 134 223 ?   ?   ?   A . n 
A 1 135 ASP 135 224 ?   ?   ?   A . n 
A 1 136 ARG 136 225 ?   ?   ?   A . n 
A 1 137 SER 137 226 ?   ?   ?   A . n 
A 1 138 GLY 138 227 ?   ?   ?   A . n 
A 1 139 TYR 139 228 ?   ?   ?   A . n 
A 1 140 SER 140 229 ?   ?   ?   A . n 
A 1 141 SER 141 230 ?   ?   ?   A . n 
A 1 142 PRO 142 231 ?   ?   ?   A . n 
A 1 143 GLY 143 232 ?   ?   ?   A . n 
A 1 144 ASP 144 233 ?   ?   ?   A . n 
A 1 145 PRO 145 234 ?   ?   ?   A . n 
A 1 146 GLY 146 235 ?   ?   ?   A . n 
A 1 147 ASP 147 236 ?   ?   ?   A . n 
A 1 148 PRO 148 237 ?   ?   ?   A . n 
A 1 149 GLY 149 238 ?   ?   ?   A . n 
A 1 150 SER 150 239 ?   ?   ?   A . n 
A 1 151 ARG 151 240 ?   ?   ?   A . n 
A 1 152 SER 152 241 ?   ?   ?   A . n 
A 1 153 ARG 153 242 ?   ?   ?   A . n 
A 1 154 ASP 154 243 ?   ?   ?   A . n 
A 1 155 PRO 155 244 ?   ?   ?   A . n 
A 1 156 ASP 156 245 ?   ?   ?   A . n 
A 1 157 LEU 157 246 ?   ?   ?   A . n 
A 1 158 PRO 158 247 ?   ?   ?   A . n 
A 1 159 ASP 159 248 ?   ?   ?   A . n 
A 1 160 PRO 160 249 ?   ?   ?   A . n 
A 1 161 PRO 161 250 ?   ?   ?   A . n 
A 1 162 THR 162 251 ?   ?   ?   A . n 
A 1 163 ARG 163 252 ?   ?   ?   A . n 
A 1 164 GLU 164 253 ?   ?   ?   A . n 
A 1 165 PRO 165 254 ?   ?   ?   A . n 
A 1 166 LYS 166 255 ?   ?   ?   A . n 
A 1 167 LYS 167 256 ?   ?   ?   A . n 
A 1 168 VAL 168 257 ?   ?   ?   A . n 
A 1 169 ALA 169 258 ?   ?   ?   A . n 
A 1 170 VAL 170 259 ?   ?   ?   A . n 
A 1 171 VAL 171 260 ?   ?   ?   A . n 
A 1 172 ARG 172 261 ?   ?   ?   A . n 
A 1 173 ASP 173 262 ?   ?   ?   A . n 
A 1 174 PRO 174 263 ?   ?   ?   A . n 
A 1 175 PRO 175 264 ?   ?   ?   A . n 
A 1 176 LYS 176 265 ?   ?   ?   A . n 
A 1 177 ASP 177 266 ?   ?   ?   A . n 
A 1 178 PRO 178 267 ?   ?   ?   A . n 
A 1 179 SER 179 268 ?   ?   ?   A . n 
A 1 180 SER 180 269 ?   ?   ?   A . n 
A 1 181 ALA 181 270 ?   ?   ?   A . n 
A 1 182 LYS 182 271 ?   ?   ?   A . n 
A 1 183 SER 183 272 ?   ?   ?   A . n 
A 1 184 ARG 184 273 ?   ?   ?   A . n 
A 1 185 LEU 185 274 ?   ?   ?   A . n 
A 1 186 GLN 186 275 ?   ?   ?   A . n 
A 1 187 THR 187 276 ?   ?   ?   A . n 
A 1 188 ALA 188 277 ?   ?   ?   A . n 
A 1 189 PRO 189 278 ?   ?   ?   A . n 
A 1 190 VAL 190 279 ?   ?   ?   A . n 
A 1 191 PRO 191 280 ?   ?   ?   A . n 
A 1 192 MET 192 281 ?   ?   ?   A . n 
A 1 193 PRO 193 282 ?   ?   ?   A . n 
A 1 194 ASP 194 283 ?   ?   ?   A . n 
A 1 195 LEU 195 284 ?   ?   ?   A . n 
A 1 196 LYS 196 285 ?   ?   ?   A . n 
A 1 197 ASN 197 286 ?   ?   ?   A . n 
A 1 198 VAL 198 287 ?   ?   ?   A . n 
A 1 199 LYS 199 288 ?   ?   ?   A . n 
A 1 200 SER 200 289 ?   ?   ?   A . n 
A 1 201 LYS 201 290 ?   ?   ?   A . n 
A 1 202 ILE 202 291 ?   ?   ?   A . n 
A 1 203 GLY 203 292 ?   ?   ?   A . n 
A 1 204 SER 204 293 ?   ?   ?   A . n 
A 1 205 THR 205 294 ?   ?   ?   A . n 
A 1 206 GLU 206 295 ?   ?   ?   A . n 
A 1 207 ASN 207 296 ?   ?   ?   A . n 
A 1 208 LEU 208 297 ?   ?   ?   A . n 
A 1 209 LYS 209 298 ?   ?   ?   A . n 
A 1 210 HIS 210 299 ?   ?   ?   A . n 
A 1 211 GLN 211 300 ?   ?   ?   A . n 
A 1 212 PRO 212 301 ?   ?   ?   A . n 
A 1 213 GLY 213 302 ?   ?   ?   A . n 
A 1 214 GLY 214 303 ?   ?   ?   A . n 
A 1 215 GLY 215 304 ?   ?   ?   A . n 
A 1 216 LYS 216 305 ?   ?   ?   A . n 
A 1 217 VAL 217 306 ?   ?   ?   A . n 
A 1 218 GLN 218 307 307 GLN GLN A . n 
A 1 219 ILE 219 308 308 ILE ILE A . n 
A 1 220 VAL 220 309 309 VAL VAL A . n 
A 1 221 TYR 221 310 310 TYR TYR A . n 
A 1 222 LYS 222 311 311 LYS LYS A . n 
A 1 223 PRO 223 312 312 PRO PRO A . n 
A 1 224 VAL 224 313 313 VAL VAL A . n 
A 1 225 ASP 225 314 314 ASP ASP A . n 
A 1 226 LEU 226 315 315 LEU LEU A . n 
A 1 227 SER 227 316 316 SER SER A . n 
A 1 228 LYS 228 317 317 LYS LYS A . n 
A 1 229 VAL 229 318 318 VAL VAL A . n 
A 1 230 THR 230 319 319 THR THR A . n 
A 1 231 SER 231 320 320 SER SER A . n 
A 1 232 LYS 232 321 321 LYS LYS A . n 
A 1 233 CYS 233 322 322 CYS CYS A . n 
A 1 234 GLY 234 323 323 GLY GLY A . n 
A 1 235 SER 235 324 324 SER SER A . n 
A 1 236 LEU 236 325 325 LEU LEU A . n 
A 1 237 GLY 237 326 326 GLY GLY A . n 
A 1 238 ASN 238 327 327 ASN ASN A . n 
A 1 239 ILE 239 328 328 ILE ILE A . n 
A 1 240 HIS 240 329 329 HIS HIS A . n 
A 1 241 HIS 241 330 330 HIS HIS A . n 
A 1 242 LYS 242 331 331 LYS LYS A . n 
A 1 243 PRO 243 332 332 PRO PRO A . n 
A 1 244 GLY 244 333 333 GLY GLY A . n 
A 1 245 GLY 245 334 334 GLY GLY A . n 
A 1 246 GLY 246 335 335 GLY GLY A . n 
A 1 247 GLN 247 336 336 GLN GLN A . n 
A 1 248 VAL 248 337 337 VAL VAL A . n 
A 1 249 GLU 249 338 338 GLU GLU A . n 
A 1 250 VAL 250 339 339 VAL VAL A . n 
A 1 251 LYS 251 340 340 LYS LYS A . n 
A 1 252 SER 252 341 341 SER SER A . n 
A 1 253 GLU 253 342 342 GLU GLU A . n 
A 1 254 LYS 254 343 343 LYS LYS A . n 
A 1 255 LEU 255 344 344 LEU LEU A . n 
A 1 256 ASP 256 345 345 ASP ASP A . n 
A 1 257 PHE 257 346 346 PHE PHE A . n 
A 1 258 LYS 258 347 347 LYS LYS A . n 
A 1 259 ASP 259 348 348 ASP ASP A . n 
A 1 260 ARG 260 349 349 ARG ARG A . n 
A 1 261 VAL 261 350 350 VAL VAL A . n 
A 1 262 GLN 262 351 351 GLN GLN A . n 
A 1 263 SER 263 352 352 SER SER A . n 
A 1 264 LYS 264 353 353 LYS LYS A . n 
A 1 265 ILE 265 354 354 ILE ILE A . n 
A 1 266 GLY 266 355 355 GLY GLY A . n 
A 1 267 SER 267 356 356 SER SER A . n 
A 1 268 LEU 268 357 357 LEU LEU A . n 
A 1 269 ASP 269 358 358 ASP ASP A . n 
A 1 270 ASN 270 359 359 ASN ASN A . n 
A 1 271 ILE 271 360 360 ILE ILE A . n 
A 1 272 THR 272 361 361 THR THR A . n 
A 1 273 HIS 273 362 362 HIS HIS A . n 
A 1 274 VAL 274 363 363 VAL VAL A . n 
A 1 275 PRO 275 364 364 PRO PRO A . n 
A 1 276 GLY 276 365 365 GLY GLY A . n 
A 1 277 GLY 277 366 366 GLY GLY A . n 
A 1 278 GLY 278 367 367 GLY GLY A . n 
A 1 279 ASN 279 368 368 ASN ASN A . n 
A 1 280 LYS 280 369 369 LYS LYS A . n 
A 1 281 LYS 281 370 370 LYS LYS A . n 
A 1 282 ILE 282 371 371 ILE ILE A . n 
A 1 283 GLU 283 372 372 GLU GLU A . n 
A 1 284 THR 284 373 373 THR THR A . n 
A 1 285 HIS 285 374 374 HIS HIS A . n 
A 1 286 LYS 286 375 375 LYS LYS A . n 
A 1 287 LEU 287 376 376 LEU LEU A . n 
A 1 288 THR 288 377 377 THR THR A . n 
A 1 289 PHE 289 378 378 PHE PHE A . n 
A 1 290 ARG 290 379 ?   ?   ?   A . n 
A 1 291 GLU 291 380 ?   ?   ?   A . n 
A 1 292 ASN 292 381 ?   ?   ?   A . n 
A 1 293 ALA 293 382 ?   ?   ?   A . n 
A 1 294 LYS 294 383 ?   ?   ?   A . n 
A 1 295 ALA 295 384 ?   ?   ?   A . n 
A 1 296 LYS 296 385 ?   ?   ?   A . n 
A 1 297 THR 297 386 ?   ?   ?   A . n 
A 1 298 ASP 298 387 ?   ?   ?   A . n 
A 1 299 HIS 299 388 ?   ?   ?   A . n 
A 1 300 GLY 300 389 ?   ?   ?   A . n 
A 1 301 ALA 301 390 ?   ?   ?   A . n 
A 1 302 GLU 302 391 ?   ?   ?   A . n 
A 1 303 ILE 303 392 ?   ?   ?   A . n 
A 1 304 VAL 304 393 ?   ?   ?   A . n 
A 1 305 TYR 305 394 ?   ?   ?   A . n 
A 1 306 LYS 306 395 ?   ?   ?   A . n 
A 1 307 ASP 307 396 ?   ?   ?   A . n 
A 1 308 PRO 308 397 ?   ?   ?   A . n 
A 1 309 VAL 309 398 ?   ?   ?   A . n 
A 1 310 VAL 310 399 ?   ?   ?   A . n 
A 1 311 ASP 311 400 ?   ?   ?   A . n 
A 1 312 GLY 312 401 ?   ?   ?   A . n 
A 1 313 ASP 313 402 ?   ?   ?   A . n 
A 1 314 ASP 314 403 ?   ?   ?   A . n 
A 1 315 ASP 315 404 ?   ?   ?   A . n 
A 1 316 PRO 316 405 ?   ?   ?   A . n 
A 1 317 ARG 317 406 ?   ?   ?   A . n 
A 1 318 HIS 318 407 ?   ?   ?   A . n 
A 1 319 LEU 319 408 ?   ?   ?   A . n 
A 1 320 SER 320 409 ?   ?   ?   A . n 
A 1 321 ASN 321 410 ?   ?   ?   A . n 
A 1 322 VAL 322 411 ?   ?   ?   A . n 
A 1 323 SER 323 412 ?   ?   ?   A . n 
A 1 324 SER 324 413 ?   ?   ?   A . n 
A 1 325 THR 325 414 ?   ?   ?   A . n 
A 1 326 GLY 326 415 ?   ?   ?   A . n 
A 1 327 SER 327 416 ?   ?   ?   A . n 
A 1 328 ILE 328 417 ?   ?   ?   A . n 
A 1 329 ASP 329 418 ?   ?   ?   A . n 
A 1 330 MET 330 419 ?   ?   ?   A . n 
A 1 331 VAL 331 420 ?   ?   ?   A . n 
A 1 332 ASP 332 421 ?   ?   ?   A . n 
A 1 333 SER 333 422 ?   ?   ?   A . n 
A 1 334 PRO 334 423 ?   ?   ?   A . n 
A 1 335 GLN 335 424 ?   ?   ?   A . n 
A 1 336 LEU 336 425 ?   ?   ?   A . n 
A 1 337 ALA 337 426 ?   ?   ?   A . n 
A 1 338 THR 338 427 ?   ?   ?   A . n 
A 1 339 LEU 339 428 ?   ?   ?   A . n 
A 1 340 ALA 340 429 ?   ?   ?   A . n 
A 1 341 ASP 341 430 ?   ?   ?   A . n 
A 1 342 GLU 342 431 ?   ?   ?   A . n 
A 1 343 VAL 343 432 ?   ?   ?   A . n 
A 1 344 SER 344 433 ?   ?   ?   A . n 
A 1 345 ALA 345 434 ?   ?   ?   A . n 
A 1 346 SER 346 435 ?   ?   ?   A . n 
A 1 347 LEU 347 436 ?   ?   ?   A . n 
A 1 348 ALA 348 437 ?   ?   ?   A . n 
A 1 349 LYS 349 438 ?   ?   ?   A . n 
A 1 350 GLN 350 439 ?   ?   ?   A . n 
A 1 351 GLY 351 440 ?   ?   ?   A . n 
A 1 352 LEU 352 441 ?   ?   ?   A . n 
B 1 1   MET 1   90  ?   ?   ?   B . n 
B 1 2   ALA 2   91  ?   ?   ?   B . n 
B 1 3   GLU 3   92  ?   ?   ?   B . n 
B 1 4   PRO 4   93  ?   ?   ?   B . n 
B 1 5   ARG 5   94  ?   ?   ?   B . n 
B 1 6   GLN 6   95  ?   ?   ?   B . n 
B 1 7   GLU 7   96  ?   ?   ?   B . n 
B 1 8   PHE 8   97  ?   ?   ?   B . n 
B 1 9   GLU 9   98  ?   ?   ?   B . n 
B 1 10  VAL 10  99  ?   ?   ?   B . n 
B 1 11  MET 11  100 ?   ?   ?   B . n 
B 1 12  GLU 12  101 ?   ?   ?   B . n 
B 1 13  ASP 13  102 ?   ?   ?   B . n 
B 1 14  HIS 14  103 ?   ?   ?   B . n 
B 1 15  ALA 15  104 ?   ?   ?   B . n 
B 1 16  GLY 16  105 ?   ?   ?   B . n 
B 1 17  THR 17  106 ?   ?   ?   B . n 
B 1 18  TYR 18  107 ?   ?   ?   B . n 
B 1 19  GLY 19  108 ?   ?   ?   B . n 
B 1 20  LEU 20  109 ?   ?   ?   B . n 
B 1 21  GLY 21  110 ?   ?   ?   B . n 
B 1 22  ASP 22  111 ?   ?   ?   B . n 
B 1 23  ARG 23  112 ?   ?   ?   B . n 
B 1 24  LYS 24  113 ?   ?   ?   B . n 
B 1 25  ASP 25  114 ?   ?   ?   B . n 
B 1 26  GLN 26  115 ?   ?   ?   B . n 
B 1 27  GLY 27  116 ?   ?   ?   B . n 
B 1 28  GLY 28  117 ?   ?   ?   B . n 
B 1 29  TYR 29  118 ?   ?   ?   B . n 
B 1 30  THR 30  119 ?   ?   ?   B . n 
B 1 31  MET 31  120 ?   ?   ?   B . n 
B 1 32  HIS 32  121 ?   ?   ?   B . n 
B 1 33  GLN 33  122 ?   ?   ?   B . n 
B 1 34  ASP 34  123 ?   ?   ?   B . n 
B 1 35  GLN 35  124 ?   ?   ?   B . n 
B 1 36  GLU 36  125 ?   ?   ?   B . n 
B 1 37  GLY 37  126 ?   ?   ?   B . n 
B 1 38  ASP 38  127 ?   ?   ?   B . n 
B 1 39  THR 39  128 ?   ?   ?   B . n 
B 1 40  ASP 40  129 ?   ?   ?   B . n 
B 1 41  ALA 41  130 ?   ?   ?   B . n 
B 1 42  GLY 42  131 ?   ?   ?   B . n 
B 1 43  LEU 43  132 ?   ?   ?   B . n 
B 1 44  LYS 44  133 ?   ?   ?   B . n 
B 1 45  ALA 45  134 ?   ?   ?   B . n 
B 1 46  GLU 46  135 ?   ?   ?   B . n 
B 1 47  GLU 47  136 ?   ?   ?   B . n 
B 1 48  ALA 48  137 ?   ?   ?   B . n 
B 1 49  GLY 49  138 ?   ?   ?   B . n 
B 1 50  ILE 50  139 ?   ?   ?   B . n 
B 1 51  GLY 51  140 ?   ?   ?   B . n 
B 1 52  ASP 52  141 ?   ?   ?   B . n 
B 1 53  THR 53  142 ?   ?   ?   B . n 
B 1 54  PRO 54  143 ?   ?   ?   B . n 
B 1 55  SER 55  144 ?   ?   ?   B . n 
B 1 56  LEU 56  145 ?   ?   ?   B . n 
B 1 57  GLU 57  146 ?   ?   ?   B . n 
B 1 58  ASP 58  147 ?   ?   ?   B . n 
B 1 59  GLU 59  148 ?   ?   ?   B . n 
B 1 60  ALA 60  149 ?   ?   ?   B . n 
B 1 61  ALA 61  150 ?   ?   ?   B . n 
B 1 62  GLY 62  151 ?   ?   ?   B . n 
B 1 63  HIS 63  152 ?   ?   ?   B . n 
B 1 64  VAL 64  153 ?   ?   ?   B . n 
B 1 65  THR 65  154 ?   ?   ?   B . n 
B 1 66  GLN 66  155 ?   ?   ?   B . n 
B 1 67  ALA 67  156 ?   ?   ?   B . n 
B 1 68  ARG 68  157 ?   ?   ?   B . n 
B 1 69  MET 69  158 ?   ?   ?   B . n 
B 1 70  VAL 70  159 ?   ?   ?   B . n 
B 1 71  SER 71  160 ?   ?   ?   B . n 
B 1 72  LYS 72  161 ?   ?   ?   B . n 
B 1 73  SER 73  162 ?   ?   ?   B . n 
B 1 74  LYS 74  163 ?   ?   ?   B . n 
B 1 75  ASP 75  164 ?   ?   ?   B . n 
B 1 76  GLY 76  165 ?   ?   ?   B . n 
B 1 77  THR 77  166 ?   ?   ?   B . n 
B 1 78  GLY 78  167 ?   ?   ?   B . n 
B 1 79  SER 79  168 ?   ?   ?   B . n 
B 1 80  ASP 80  169 ?   ?   ?   B . n 
B 1 81  ASP 81  170 ?   ?   ?   B . n 
B 1 82  LYS 82  171 ?   ?   ?   B . n 
B 1 83  LYS 83  172 ?   ?   ?   B . n 
B 1 84  ALA 84  173 ?   ?   ?   B . n 
B 1 85  LYS 85  174 ?   ?   ?   B . n 
B 1 86  GLY 86  175 ?   ?   ?   B . n 
B 1 87  ALA 87  176 ?   ?   ?   B . n 
B 1 88  ASP 88  177 ?   ?   ?   B . n 
B 1 89  GLY 89  178 ?   ?   ?   B . n 
B 1 90  LYS 90  179 ?   ?   ?   B . n 
B 1 91  THR 91  180 ?   ?   ?   B . n 
B 1 92  LYS 92  181 ?   ?   ?   B . n 
B 1 93  ILE 93  182 ?   ?   ?   B . n 
B 1 94  ALA 94  183 ?   ?   ?   B . n 
B 1 95  THR 95  184 ?   ?   ?   B . n 
B 1 96  PRO 96  185 ?   ?   ?   B . n 
B 1 97  ARG 97  186 ?   ?   ?   B . n 
B 1 98  GLY 98  187 ?   ?   ?   B . n 
B 1 99  ALA 99  188 ?   ?   ?   B . n 
B 1 100 ALA 100 189 ?   ?   ?   B . n 
B 1 101 PRO 101 190 ?   ?   ?   B . n 
B 1 102 PRO 102 191 ?   ?   ?   B . n 
B 1 103 GLY 103 192 ?   ?   ?   B . n 
B 1 104 GLN 104 193 ?   ?   ?   B . n 
B 1 105 LYS 105 194 ?   ?   ?   B . n 
B 1 106 GLY 106 195 ?   ?   ?   B . n 
B 1 107 GLN 107 196 ?   ?   ?   B . n 
B 1 108 ALA 108 197 ?   ?   ?   B . n 
B 1 109 ASN 109 198 ?   ?   ?   B . n 
B 1 110 ALA 110 199 ?   ?   ?   B . n 
B 1 111 THR 111 200 ?   ?   ?   B . n 
B 1 112 ARG 112 201 ?   ?   ?   B . n 
B 1 113 ILE 113 202 ?   ?   ?   B . n 
B 1 114 PRO 114 203 ?   ?   ?   B . n 
B 1 115 ALA 115 204 ?   ?   ?   B . n 
B 1 116 LYS 116 205 ?   ?   ?   B . n 
B 1 117 THR 117 206 ?   ?   ?   B . n 
B 1 118 PRO 118 207 ?   ?   ?   B . n 
B 1 119 PRO 119 208 ?   ?   ?   B . n 
B 1 120 ALA 120 209 ?   ?   ?   B . n 
B 1 121 PRO 121 210 ?   ?   ?   B . n 
B 1 122 LYS 122 211 ?   ?   ?   B . n 
B 1 123 ASP 123 212 ?   ?   ?   B . n 
B 1 124 PRO 124 213 ?   ?   ?   B . n 
B 1 125 PRO 125 214 ?   ?   ?   B . n 
B 1 126 SER 126 215 ?   ?   ?   B . n 
B 1 127 SER 127 216 ?   ?   ?   B . n 
B 1 128 GLY 128 217 ?   ?   ?   B . n 
B 1 129 GLU 129 218 ?   ?   ?   B . n 
B 1 130 PRO 130 219 ?   ?   ?   B . n 
B 1 131 PRO 131 220 ?   ?   ?   B . n 
B 1 132 LYS 132 221 ?   ?   ?   B . n 
B 1 133 SER 133 222 ?   ?   ?   B . n 
B 1 134 GLY 134 223 ?   ?   ?   B . n 
B 1 135 ASP 135 224 ?   ?   ?   B . n 
B 1 136 ARG 136 225 ?   ?   ?   B . n 
B 1 137 SER 137 226 ?   ?   ?   B . n 
B 1 138 GLY 138 227 ?   ?   ?   B . n 
B 1 139 TYR 139 228 ?   ?   ?   B . n 
B 1 140 SER 140 229 ?   ?   ?   B . n 
B 1 141 SER 141 230 ?   ?   ?   B . n 
B 1 142 PRO 142 231 ?   ?   ?   B . n 
B 1 143 GLY 143 232 ?   ?   ?   B . n 
B 1 144 ASP 144 233 ?   ?   ?   B . n 
B 1 145 PRO 145 234 ?   ?   ?   B . n 
B 1 146 GLY 146 235 ?   ?   ?   B . n 
B 1 147 ASP 147 236 ?   ?   ?   B . n 
B 1 148 PRO 148 237 ?   ?   ?   B . n 
B 1 149 GLY 149 238 ?   ?   ?   B . n 
B 1 150 SER 150 239 ?   ?   ?   B . n 
B 1 151 ARG 151 240 ?   ?   ?   B . n 
B 1 152 SER 152 241 ?   ?   ?   B . n 
B 1 153 ARG 153 242 ?   ?   ?   B . n 
B 1 154 ASP 154 243 ?   ?   ?   B . n 
B 1 155 PRO 155 244 ?   ?   ?   B . n 
B 1 156 ASP 156 245 ?   ?   ?   B . n 
B 1 157 LEU 157 246 ?   ?   ?   B . n 
B 1 158 PRO 158 247 ?   ?   ?   B . n 
B 1 159 ASP 159 248 ?   ?   ?   B . n 
B 1 160 PRO 160 249 ?   ?   ?   B . n 
B 1 161 PRO 161 250 ?   ?   ?   B . n 
B 1 162 THR 162 251 ?   ?   ?   B . n 
B 1 163 ARG 163 252 ?   ?   ?   B . n 
B 1 164 GLU 164 253 ?   ?   ?   B . n 
B 1 165 PRO 165 254 ?   ?   ?   B . n 
B 1 166 LYS 166 255 ?   ?   ?   B . n 
B 1 167 LYS 167 256 ?   ?   ?   B . n 
B 1 168 VAL 168 257 ?   ?   ?   B . n 
B 1 169 ALA 169 258 ?   ?   ?   B . n 
B 1 170 VAL 170 259 ?   ?   ?   B . n 
B 1 171 VAL 171 260 ?   ?   ?   B . n 
B 1 172 ARG 172 261 ?   ?   ?   B . n 
B 1 173 ASP 173 262 ?   ?   ?   B . n 
B 1 174 PRO 174 263 ?   ?   ?   B . n 
B 1 175 PRO 175 264 ?   ?   ?   B . n 
B 1 176 LYS 176 265 ?   ?   ?   B . n 
B 1 177 ASP 177 266 ?   ?   ?   B . n 
B 1 178 PRO 178 267 ?   ?   ?   B . n 
B 1 179 SER 179 268 ?   ?   ?   B . n 
B 1 180 SER 180 269 ?   ?   ?   B . n 
B 1 181 ALA 181 270 ?   ?   ?   B . n 
B 1 182 LYS 182 271 ?   ?   ?   B . n 
B 1 183 SER 183 272 ?   ?   ?   B . n 
B 1 184 ARG 184 273 ?   ?   ?   B . n 
B 1 185 LEU 185 274 ?   ?   ?   B . n 
B 1 186 GLN 186 275 ?   ?   ?   B . n 
B 1 187 THR 187 276 ?   ?   ?   B . n 
B 1 188 ALA 188 277 ?   ?   ?   B . n 
B 1 189 PRO 189 278 ?   ?   ?   B . n 
B 1 190 VAL 190 279 ?   ?   ?   B . n 
B 1 191 PRO 191 280 ?   ?   ?   B . n 
B 1 192 MET 192 281 ?   ?   ?   B . n 
B 1 193 PRO 193 282 ?   ?   ?   B . n 
B 1 194 ASP 194 283 ?   ?   ?   B . n 
B 1 195 LEU 195 284 ?   ?   ?   B . n 
B 1 196 LYS 196 285 ?   ?   ?   B . n 
B 1 197 ASN 197 286 ?   ?   ?   B . n 
B 1 198 VAL 198 287 ?   ?   ?   B . n 
B 1 199 LYS 199 288 ?   ?   ?   B . n 
B 1 200 SER 200 289 ?   ?   ?   B . n 
B 1 201 LYS 201 290 ?   ?   ?   B . n 
B 1 202 ILE 202 291 ?   ?   ?   B . n 
B 1 203 GLY 203 292 ?   ?   ?   B . n 
B 1 204 SER 204 293 ?   ?   ?   B . n 
B 1 205 THR 205 294 ?   ?   ?   B . n 
B 1 206 GLU 206 295 ?   ?   ?   B . n 
B 1 207 ASN 207 296 ?   ?   ?   B . n 
B 1 208 LEU 208 297 ?   ?   ?   B . n 
B 1 209 LYS 209 298 ?   ?   ?   B . n 
B 1 210 HIS 210 299 ?   ?   ?   B . n 
B 1 211 GLN 211 300 ?   ?   ?   B . n 
B 1 212 PRO 212 301 ?   ?   ?   B . n 
B 1 213 GLY 213 302 ?   ?   ?   B . n 
B 1 214 GLY 214 303 ?   ?   ?   B . n 
B 1 215 GLY 215 304 ?   ?   ?   B . n 
B 1 216 LYS 216 305 ?   ?   ?   B . n 
B 1 217 VAL 217 306 ?   ?   ?   B . n 
B 1 218 GLN 218 307 307 GLN GLN B . n 
B 1 219 ILE 219 308 308 ILE ILE B . n 
B 1 220 VAL 220 309 309 VAL VAL B . n 
B 1 221 TYR 221 310 310 TYR TYR B . n 
B 1 222 LYS 222 311 311 LYS LYS B . n 
B 1 223 PRO 223 312 312 PRO PRO B . n 
B 1 224 VAL 224 313 313 VAL VAL B . n 
B 1 225 ASP 225 314 314 ASP ASP B . n 
B 1 226 LEU 226 315 315 LEU LEU B . n 
B 1 227 SER 227 316 316 SER SER B . n 
B 1 228 LYS 228 317 317 LYS LYS B . n 
B 1 229 VAL 229 318 318 VAL VAL B . n 
B 1 230 THR 230 319 319 THR THR B . n 
B 1 231 SER 231 320 320 SER SER B . n 
B 1 232 LYS 232 321 321 LYS LYS B . n 
B 1 233 CYS 233 322 322 CYS CYS B . n 
B 1 234 GLY 234 323 323 GLY GLY B . n 
B 1 235 SER 235 324 324 SER SER B . n 
B 1 236 LEU 236 325 325 LEU LEU B . n 
B 1 237 GLY 237 326 326 GLY GLY B . n 
B 1 238 ASN 238 327 327 ASN ASN B . n 
B 1 239 ILE 239 328 328 ILE ILE B . n 
B 1 240 HIS 240 329 329 HIS HIS B . n 
B 1 241 HIS 241 330 330 HIS HIS B . n 
B 1 242 LYS 242 331 331 LYS LYS B . n 
B 1 243 PRO 243 332 332 PRO PRO B . n 
B 1 244 GLY 244 333 333 GLY GLY B . n 
B 1 245 GLY 245 334 334 GLY GLY B . n 
B 1 246 GLY 246 335 335 GLY GLY B . n 
B 1 247 GLN 247 336 336 GLN GLN B . n 
B 1 248 VAL 248 337 337 VAL VAL B . n 
B 1 249 GLU 249 338 338 GLU GLU B . n 
B 1 250 VAL 250 339 339 VAL VAL B . n 
B 1 251 LYS 251 340 340 LYS LYS B . n 
B 1 252 SER 252 341 341 SER SER B . n 
B 1 253 GLU 253 342 342 GLU GLU B . n 
B 1 254 LYS 254 343 343 LYS LYS B . n 
B 1 255 LEU 255 344 344 LEU LEU B . n 
B 1 256 ASP 256 345 345 ASP ASP B . n 
B 1 257 PHE 257 346 346 PHE PHE B . n 
B 1 258 LYS 258 347 347 LYS LYS B . n 
B 1 259 ASP 259 348 348 ASP ASP B . n 
B 1 260 ARG 260 349 349 ARG ARG B . n 
B 1 261 VAL 261 350 350 VAL VAL B . n 
B 1 262 GLN 262 351 351 GLN GLN B . n 
B 1 263 SER 263 352 352 SER SER B . n 
B 1 264 LYS 264 353 353 LYS LYS B . n 
B 1 265 ILE 265 354 354 ILE ILE B . n 
B 1 266 GLY 266 355 355 GLY GLY B . n 
B 1 267 SER 267 356 356 SER SER B . n 
B 1 268 LEU 268 357 357 LEU LEU B . n 
B 1 269 ASP 269 358 358 ASP ASP B . n 
B 1 270 ASN 270 359 359 ASN ASN B . n 
B 1 271 ILE 271 360 360 ILE ILE B . n 
B 1 272 THR 272 361 361 THR THR B . n 
B 1 273 HIS 273 362 362 HIS HIS B . n 
B 1 274 VAL 274 363 363 VAL VAL B . n 
B 1 275 PRO 275 364 364 PRO PRO B . n 
B 1 276 GLY 276 365 365 GLY GLY B . n 
B 1 277 GLY 277 366 366 GLY GLY B . n 
B 1 278 GLY 278 367 367 GLY GLY B . n 
B 1 279 ASN 279 368 368 ASN ASN B . n 
B 1 280 LYS 280 369 369 LYS LYS B . n 
B 1 281 LYS 281 370 370 LYS LYS B . n 
B 1 282 ILE 282 371 371 ILE ILE B . n 
B 1 283 GLU 283 372 372 GLU GLU B . n 
B 1 284 THR 284 373 373 THR THR B . n 
B 1 285 HIS 285 374 374 HIS HIS B . n 
B 1 286 LYS 286 375 375 LYS LYS B . n 
B 1 287 LEU 287 376 376 LEU LEU B . n 
B 1 288 THR 288 377 377 THR THR B . n 
B 1 289 PHE 289 378 378 PHE PHE B . n 
B 1 290 ARG 290 379 ?   ?   ?   B . n 
B 1 291 GLU 291 380 ?   ?   ?   B . n 
B 1 292 ASN 292 381 ?   ?   ?   B . n 
B 1 293 ALA 293 382 ?   ?   ?   B . n 
B 1 294 LYS 294 383 ?   ?   ?   B . n 
B 1 295 ALA 295 384 ?   ?   ?   B . n 
B 1 296 LYS 296 385 ?   ?   ?   B . n 
B 1 297 THR 297 386 ?   ?   ?   B . n 
B 1 298 ASP 298 387 ?   ?   ?   B . n 
B 1 299 HIS 299 388 ?   ?   ?   B . n 
B 1 300 GLY 300 389 ?   ?   ?   B . n 
B 1 301 ALA 301 390 ?   ?   ?   B . n 
B 1 302 GLU 302 391 ?   ?   ?   B . n 
B 1 303 ILE 303 392 ?   ?   ?   B . n 
B 1 304 VAL 304 393 ?   ?   ?   B . n 
B 1 305 TYR 305 394 ?   ?   ?   B . n 
B 1 306 LYS 306 395 ?   ?   ?   B . n 
B 1 307 ASP 307 396 ?   ?   ?   B . n 
B 1 308 PRO 308 397 ?   ?   ?   B . n 
B 1 309 VAL 309 398 ?   ?   ?   B . n 
B 1 310 VAL 310 399 ?   ?   ?   B . n 
B 1 311 ASP 311 400 ?   ?   ?   B . n 
B 1 312 GLY 312 401 ?   ?   ?   B . n 
B 1 313 ASP 313 402 ?   ?   ?   B . n 
B 1 314 ASP 314 403 ?   ?   ?   B . n 
B 1 315 ASP 315 404 ?   ?   ?   B . n 
B 1 316 PRO 316 405 ?   ?   ?   B . n 
B 1 317 ARG 317 406 ?   ?   ?   B . n 
B 1 318 HIS 318 407 ?   ?   ?   B . n 
B 1 319 LEU 319 408 ?   ?   ?   B . n 
B 1 320 SER 320 409 ?   ?   ?   B . n 
B 1 321 ASN 321 410 ?   ?   ?   B . n 
B 1 322 VAL 322 411 ?   ?   ?   B . n 
B 1 323 SER 323 412 ?   ?   ?   B . n 
B 1 324 SER 324 413 ?   ?   ?   B . n 
B 1 325 THR 325 414 ?   ?   ?   B . n 
B 1 326 GLY 326 415 ?   ?   ?   B . n 
B 1 327 SER 327 416 ?   ?   ?   B . n 
B 1 328 ILE 328 417 ?   ?   ?   B . n 
B 1 329 ASP 329 418 ?   ?   ?   B . n 
B 1 330 MET 330 419 ?   ?   ?   B . n 
B 1 331 VAL 331 420 ?   ?   ?   B . n 
B 1 332 ASP 332 421 ?   ?   ?   B . n 
B 1 333 SER 333 422 ?   ?   ?   B . n 
B 1 334 PRO 334 423 ?   ?   ?   B . n 
B 1 335 GLN 335 424 ?   ?   ?   B . n 
B 1 336 LEU 336 425 ?   ?   ?   B . n 
B 1 337 ALA 337 426 ?   ?   ?   B . n 
B 1 338 THR 338 427 ?   ?   ?   B . n 
B 1 339 LEU 339 428 ?   ?   ?   B . n 
B 1 340 ALA 340 429 ?   ?   ?   B . n 
B 1 341 ASP 341 430 ?   ?   ?   B . n 
B 1 342 GLU 342 431 ?   ?   ?   B . n 
B 1 343 VAL 343 432 ?   ?   ?   B . n 
B 1 344 SER 344 433 ?   ?   ?   B . n 
B 1 345 ALA 345 434 ?   ?   ?   B . n 
B 1 346 SER 346 435 ?   ?   ?   B . n 
B 1 347 LEU 347 436 ?   ?   ?   B . n 
B 1 348 ALA 348 437 ?   ?   ?   B . n 
B 1 349 LYS 349 438 ?   ?   ?   B . n 
B 1 350 GLN 350 439 ?   ?   ?   B . n 
B 1 351 GLY 351 440 ?   ?   ?   B . n 
B 1 352 LEU 352 441 ?   ?   ?   B . n 
C 1 1   MET 1   90  ?   ?   ?   C . n 
C 1 2   ALA 2   91  ?   ?   ?   C . n 
C 1 3   GLU 3   92  ?   ?   ?   C . n 
C 1 4   PRO 4   93  ?   ?   ?   C . n 
C 1 5   ARG 5   94  ?   ?   ?   C . n 
C 1 6   GLN 6   95  ?   ?   ?   C . n 
C 1 7   GLU 7   96  ?   ?   ?   C . n 
C 1 8   PHE 8   97  ?   ?   ?   C . n 
C 1 9   GLU 9   98  ?   ?   ?   C . n 
C 1 10  VAL 10  99  ?   ?   ?   C . n 
C 1 11  MET 11  100 ?   ?   ?   C . n 
C 1 12  GLU 12  101 ?   ?   ?   C . n 
C 1 13  ASP 13  102 ?   ?   ?   C . n 
C 1 14  HIS 14  103 ?   ?   ?   C . n 
C 1 15  ALA 15  104 ?   ?   ?   C . n 
C 1 16  GLY 16  105 ?   ?   ?   C . n 
C 1 17  THR 17  106 ?   ?   ?   C . n 
C 1 18  TYR 18  107 ?   ?   ?   C . n 
C 1 19  GLY 19  108 ?   ?   ?   C . n 
C 1 20  LEU 20  109 ?   ?   ?   C . n 
C 1 21  GLY 21  110 ?   ?   ?   C . n 
C 1 22  ASP 22  111 ?   ?   ?   C . n 
C 1 23  ARG 23  112 ?   ?   ?   C . n 
C 1 24  LYS 24  113 ?   ?   ?   C . n 
C 1 25  ASP 25  114 ?   ?   ?   C . n 
C 1 26  GLN 26  115 ?   ?   ?   C . n 
C 1 27  GLY 27  116 ?   ?   ?   C . n 
C 1 28  GLY 28  117 ?   ?   ?   C . n 
C 1 29  TYR 29  118 ?   ?   ?   C . n 
C 1 30  THR 30  119 ?   ?   ?   C . n 
C 1 31  MET 31  120 ?   ?   ?   C . n 
C 1 32  HIS 32  121 ?   ?   ?   C . n 
C 1 33  GLN 33  122 ?   ?   ?   C . n 
C 1 34  ASP 34  123 ?   ?   ?   C . n 
C 1 35  GLN 35  124 ?   ?   ?   C . n 
C 1 36  GLU 36  125 ?   ?   ?   C . n 
C 1 37  GLY 37  126 ?   ?   ?   C . n 
C 1 38  ASP 38  127 ?   ?   ?   C . n 
C 1 39  THR 39  128 ?   ?   ?   C . n 
C 1 40  ASP 40  129 ?   ?   ?   C . n 
C 1 41  ALA 41  130 ?   ?   ?   C . n 
C 1 42  GLY 42  131 ?   ?   ?   C . n 
C 1 43  LEU 43  132 ?   ?   ?   C . n 
C 1 44  LYS 44  133 ?   ?   ?   C . n 
C 1 45  ALA 45  134 ?   ?   ?   C . n 
C 1 46  GLU 46  135 ?   ?   ?   C . n 
C 1 47  GLU 47  136 ?   ?   ?   C . n 
C 1 48  ALA 48  137 ?   ?   ?   C . n 
C 1 49  GLY 49  138 ?   ?   ?   C . n 
C 1 50  ILE 50  139 ?   ?   ?   C . n 
C 1 51  GLY 51  140 ?   ?   ?   C . n 
C 1 52  ASP 52  141 ?   ?   ?   C . n 
C 1 53  THR 53  142 ?   ?   ?   C . n 
C 1 54  PRO 54  143 ?   ?   ?   C . n 
C 1 55  SER 55  144 ?   ?   ?   C . n 
C 1 56  LEU 56  145 ?   ?   ?   C . n 
C 1 57  GLU 57  146 ?   ?   ?   C . n 
C 1 58  ASP 58  147 ?   ?   ?   C . n 
C 1 59  GLU 59  148 ?   ?   ?   C . n 
C 1 60  ALA 60  149 ?   ?   ?   C . n 
C 1 61  ALA 61  150 ?   ?   ?   C . n 
C 1 62  GLY 62  151 ?   ?   ?   C . n 
C 1 63  HIS 63  152 ?   ?   ?   C . n 
C 1 64  VAL 64  153 ?   ?   ?   C . n 
C 1 65  THR 65  154 ?   ?   ?   C . n 
C 1 66  GLN 66  155 ?   ?   ?   C . n 
C 1 67  ALA 67  156 ?   ?   ?   C . n 
C 1 68  ARG 68  157 ?   ?   ?   C . n 
C 1 69  MET 69  158 ?   ?   ?   C . n 
C 1 70  VAL 70  159 ?   ?   ?   C . n 
C 1 71  SER 71  160 ?   ?   ?   C . n 
C 1 72  LYS 72  161 ?   ?   ?   C . n 
C 1 73  SER 73  162 ?   ?   ?   C . n 
C 1 74  LYS 74  163 ?   ?   ?   C . n 
C 1 75  ASP 75  164 ?   ?   ?   C . n 
C 1 76  GLY 76  165 ?   ?   ?   C . n 
C 1 77  THR 77  166 ?   ?   ?   C . n 
C 1 78  GLY 78  167 ?   ?   ?   C . n 
C 1 79  SER 79  168 ?   ?   ?   C . n 
C 1 80  ASP 80  169 ?   ?   ?   C . n 
C 1 81  ASP 81  170 ?   ?   ?   C . n 
C 1 82  LYS 82  171 ?   ?   ?   C . n 
C 1 83  LYS 83  172 ?   ?   ?   C . n 
C 1 84  ALA 84  173 ?   ?   ?   C . n 
C 1 85  LYS 85  174 ?   ?   ?   C . n 
C 1 86  GLY 86  175 ?   ?   ?   C . n 
C 1 87  ALA 87  176 ?   ?   ?   C . n 
C 1 88  ASP 88  177 ?   ?   ?   C . n 
C 1 89  GLY 89  178 ?   ?   ?   C . n 
C 1 90  LYS 90  179 ?   ?   ?   C . n 
C 1 91  THR 91  180 ?   ?   ?   C . n 
C 1 92  LYS 92  181 ?   ?   ?   C . n 
C 1 93  ILE 93  182 ?   ?   ?   C . n 
C 1 94  ALA 94  183 ?   ?   ?   C . n 
C 1 95  THR 95  184 ?   ?   ?   C . n 
C 1 96  PRO 96  185 ?   ?   ?   C . n 
C 1 97  ARG 97  186 ?   ?   ?   C . n 
C 1 98  GLY 98  187 ?   ?   ?   C . n 
C 1 99  ALA 99  188 ?   ?   ?   C . n 
C 1 100 ALA 100 189 ?   ?   ?   C . n 
C 1 101 PRO 101 190 ?   ?   ?   C . n 
C 1 102 PRO 102 191 ?   ?   ?   C . n 
C 1 103 GLY 103 192 ?   ?   ?   C . n 
C 1 104 GLN 104 193 ?   ?   ?   C . n 
C 1 105 LYS 105 194 ?   ?   ?   C . n 
C 1 106 GLY 106 195 ?   ?   ?   C . n 
C 1 107 GLN 107 196 ?   ?   ?   C . n 
C 1 108 ALA 108 197 ?   ?   ?   C . n 
C 1 109 ASN 109 198 ?   ?   ?   C . n 
C 1 110 ALA 110 199 ?   ?   ?   C . n 
C 1 111 THR 111 200 ?   ?   ?   C . n 
C 1 112 ARG 112 201 ?   ?   ?   C . n 
C 1 113 ILE 113 202 ?   ?   ?   C . n 
C 1 114 PRO 114 203 ?   ?   ?   C . n 
C 1 115 ALA 115 204 ?   ?   ?   C . n 
C 1 116 LYS 116 205 ?   ?   ?   C . n 
C 1 117 THR 117 206 ?   ?   ?   C . n 
C 1 118 PRO 118 207 ?   ?   ?   C . n 
C 1 119 PRO 119 208 ?   ?   ?   C . n 
C 1 120 ALA 120 209 ?   ?   ?   C . n 
C 1 121 PRO 121 210 ?   ?   ?   C . n 
C 1 122 LYS 122 211 ?   ?   ?   C . n 
C 1 123 ASP 123 212 ?   ?   ?   C . n 
C 1 124 PRO 124 213 ?   ?   ?   C . n 
C 1 125 PRO 125 214 ?   ?   ?   C . n 
C 1 126 SER 126 215 ?   ?   ?   C . n 
C 1 127 SER 127 216 ?   ?   ?   C . n 
C 1 128 GLY 128 217 ?   ?   ?   C . n 
C 1 129 GLU 129 218 ?   ?   ?   C . n 
C 1 130 PRO 130 219 ?   ?   ?   C . n 
C 1 131 PRO 131 220 ?   ?   ?   C . n 
C 1 132 LYS 132 221 ?   ?   ?   C . n 
C 1 133 SER 133 222 ?   ?   ?   C . n 
C 1 134 GLY 134 223 ?   ?   ?   C . n 
C 1 135 ASP 135 224 ?   ?   ?   C . n 
C 1 136 ARG 136 225 ?   ?   ?   C . n 
C 1 137 SER 137 226 ?   ?   ?   C . n 
C 1 138 GLY 138 227 ?   ?   ?   C . n 
C 1 139 TYR 139 228 ?   ?   ?   C . n 
C 1 140 SER 140 229 ?   ?   ?   C . n 
C 1 141 SER 141 230 ?   ?   ?   C . n 
C 1 142 PRO 142 231 ?   ?   ?   C . n 
C 1 143 GLY 143 232 ?   ?   ?   C . n 
C 1 144 ASP 144 233 ?   ?   ?   C . n 
C 1 145 PRO 145 234 ?   ?   ?   C . n 
C 1 146 GLY 146 235 ?   ?   ?   C . n 
C 1 147 ASP 147 236 ?   ?   ?   C . n 
C 1 148 PRO 148 237 ?   ?   ?   C . n 
C 1 149 GLY 149 238 ?   ?   ?   C . n 
C 1 150 SER 150 239 ?   ?   ?   C . n 
C 1 151 ARG 151 240 ?   ?   ?   C . n 
C 1 152 SER 152 241 ?   ?   ?   C . n 
C 1 153 ARG 153 242 ?   ?   ?   C . n 
C 1 154 ASP 154 243 ?   ?   ?   C . n 
C 1 155 PRO 155 244 ?   ?   ?   C . n 
C 1 156 ASP 156 245 ?   ?   ?   C . n 
C 1 157 LEU 157 246 ?   ?   ?   C . n 
C 1 158 PRO 158 247 ?   ?   ?   C . n 
C 1 159 ASP 159 248 ?   ?   ?   C . n 
C 1 160 PRO 160 249 ?   ?   ?   C . n 
C 1 161 PRO 161 250 ?   ?   ?   C . n 
C 1 162 THR 162 251 ?   ?   ?   C . n 
C 1 163 ARG 163 252 ?   ?   ?   C . n 
C 1 164 GLU 164 253 ?   ?   ?   C . n 
C 1 165 PRO 165 254 ?   ?   ?   C . n 
C 1 166 LYS 166 255 ?   ?   ?   C . n 
C 1 167 LYS 167 256 ?   ?   ?   C . n 
C 1 168 VAL 168 257 ?   ?   ?   C . n 
C 1 169 ALA 169 258 ?   ?   ?   C . n 
C 1 170 VAL 170 259 ?   ?   ?   C . n 
C 1 171 VAL 171 260 ?   ?   ?   C . n 
C 1 172 ARG 172 261 ?   ?   ?   C . n 
C 1 173 ASP 173 262 ?   ?   ?   C . n 
C 1 174 PRO 174 263 ?   ?   ?   C . n 
C 1 175 PRO 175 264 ?   ?   ?   C . n 
C 1 176 LYS 176 265 ?   ?   ?   C . n 
C 1 177 ASP 177 266 ?   ?   ?   C . n 
C 1 178 PRO 178 267 ?   ?   ?   C . n 
C 1 179 SER 179 268 ?   ?   ?   C . n 
C 1 180 SER 180 269 ?   ?   ?   C . n 
C 1 181 ALA 181 270 ?   ?   ?   C . n 
C 1 182 LYS 182 271 ?   ?   ?   C . n 
C 1 183 SER 183 272 ?   ?   ?   C . n 
C 1 184 ARG 184 273 ?   ?   ?   C . n 
C 1 185 LEU 185 274 ?   ?   ?   C . n 
C 1 186 GLN 186 275 ?   ?   ?   C . n 
C 1 187 THR 187 276 ?   ?   ?   C . n 
C 1 188 ALA 188 277 ?   ?   ?   C . n 
C 1 189 PRO 189 278 ?   ?   ?   C . n 
C 1 190 VAL 190 279 ?   ?   ?   C . n 
C 1 191 PRO 191 280 ?   ?   ?   C . n 
C 1 192 MET 192 281 ?   ?   ?   C . n 
C 1 193 PRO 193 282 ?   ?   ?   C . n 
C 1 194 ASP 194 283 ?   ?   ?   C . n 
C 1 195 LEU 195 284 ?   ?   ?   C . n 
C 1 196 LYS 196 285 ?   ?   ?   C . n 
C 1 197 ASN 197 286 ?   ?   ?   C . n 
C 1 198 VAL 198 287 ?   ?   ?   C . n 
C 1 199 LYS 199 288 ?   ?   ?   C . n 
C 1 200 SER 200 289 ?   ?   ?   C . n 
C 1 201 LYS 201 290 ?   ?   ?   C . n 
C 1 202 ILE 202 291 ?   ?   ?   C . n 
C 1 203 GLY 203 292 ?   ?   ?   C . n 
C 1 204 SER 204 293 ?   ?   ?   C . n 
C 1 205 THR 205 294 ?   ?   ?   C . n 
C 1 206 GLU 206 295 ?   ?   ?   C . n 
C 1 207 ASN 207 296 ?   ?   ?   C . n 
C 1 208 LEU 208 297 ?   ?   ?   C . n 
C 1 209 LYS 209 298 ?   ?   ?   C . n 
C 1 210 HIS 210 299 ?   ?   ?   C . n 
C 1 211 GLN 211 300 ?   ?   ?   C . n 
C 1 212 PRO 212 301 ?   ?   ?   C . n 
C 1 213 GLY 213 302 ?   ?   ?   C . n 
C 1 214 GLY 214 303 ?   ?   ?   C . n 
C 1 215 GLY 215 304 ?   ?   ?   C . n 
C 1 216 LYS 216 305 ?   ?   ?   C . n 
C 1 217 VAL 217 306 ?   ?   ?   C . n 
C 1 218 GLN 218 307 307 GLN GLN C . n 
C 1 219 ILE 219 308 308 ILE ILE C . n 
C 1 220 VAL 220 309 309 VAL VAL C . n 
C 1 221 TYR 221 310 310 TYR TYR C . n 
C 1 222 LYS 222 311 311 LYS LYS C . n 
C 1 223 PRO 223 312 312 PRO PRO C . n 
C 1 224 VAL 224 313 313 VAL VAL C . n 
C 1 225 ASP 225 314 314 ASP ASP C . n 
C 1 226 LEU 226 315 315 LEU LEU C . n 
C 1 227 SER 227 316 316 SER SER C . n 
C 1 228 LYS 228 317 317 LYS LYS C . n 
C 1 229 VAL 229 318 318 VAL VAL C . n 
C 1 230 THR 230 319 319 THR THR C . n 
C 1 231 SER 231 320 320 SER SER C . n 
C 1 232 LYS 232 321 321 LYS LYS C . n 
C 1 233 CYS 233 322 322 CYS CYS C . n 
C 1 234 GLY 234 323 323 GLY GLY C . n 
C 1 235 SER 235 324 324 SER SER C . n 
C 1 236 LEU 236 325 325 LEU LEU C . n 
C 1 237 GLY 237 326 326 GLY GLY C . n 
C 1 238 ASN 238 327 327 ASN ASN C . n 
C 1 239 ILE 239 328 328 ILE ILE C . n 
C 1 240 HIS 240 329 329 HIS HIS C . n 
C 1 241 HIS 241 330 330 HIS HIS C . n 
C 1 242 LYS 242 331 331 LYS LYS C . n 
C 1 243 PRO 243 332 332 PRO PRO C . n 
C 1 244 GLY 244 333 333 GLY GLY C . n 
C 1 245 GLY 245 334 334 GLY GLY C . n 
C 1 246 GLY 246 335 335 GLY GLY C . n 
C 1 247 GLN 247 336 336 GLN GLN C . n 
C 1 248 VAL 248 337 337 VAL VAL C . n 
C 1 249 GLU 249 338 338 GLU GLU C . n 
C 1 250 VAL 250 339 339 VAL VAL C . n 
C 1 251 LYS 251 340 340 LYS LYS C . n 
C 1 252 SER 252 341 341 SER SER C . n 
C 1 253 GLU 253 342 342 GLU GLU C . n 
C 1 254 LYS 254 343 343 LYS LYS C . n 
C 1 255 LEU 255 344 344 LEU LEU C . n 
C 1 256 ASP 256 345 345 ASP ASP C . n 
C 1 257 PHE 257 346 346 PHE PHE C . n 
C 1 258 LYS 258 347 347 LYS LYS C . n 
C 1 259 ASP 259 348 348 ASP ASP C . n 
C 1 260 ARG 260 349 349 ARG ARG C . n 
C 1 261 VAL 261 350 350 VAL VAL C . n 
C 1 262 GLN 262 351 351 GLN GLN C . n 
C 1 263 SER 263 352 352 SER SER C . n 
C 1 264 LYS 264 353 353 LYS LYS C . n 
C 1 265 ILE 265 354 354 ILE ILE C . n 
C 1 266 GLY 266 355 355 GLY GLY C . n 
C 1 267 SER 267 356 356 SER SER C . n 
C 1 268 LEU 268 357 357 LEU LEU C . n 
C 1 269 ASP 269 358 358 ASP ASP C . n 
C 1 270 ASN 270 359 359 ASN ASN C . n 
C 1 271 ILE 271 360 360 ILE ILE C . n 
C 1 272 THR 272 361 361 THR THR C . n 
C 1 273 HIS 273 362 362 HIS HIS C . n 
C 1 274 VAL 274 363 363 VAL VAL C . n 
C 1 275 PRO 275 364 364 PRO PRO C . n 
C 1 276 GLY 276 365 365 GLY GLY C . n 
C 1 277 GLY 277 366 366 GLY GLY C . n 
C 1 278 GLY 278 367 367 GLY GLY C . n 
C 1 279 ASN 279 368 368 ASN ASN C . n 
C 1 280 LYS 280 369 369 LYS LYS C . n 
C 1 281 LYS 281 370 370 LYS LYS C . n 
C 1 282 ILE 282 371 371 ILE ILE C . n 
C 1 283 GLU 283 372 372 GLU GLU C . n 
C 1 284 THR 284 373 373 THR THR C . n 
C 1 285 HIS 285 374 374 HIS HIS C . n 
C 1 286 LYS 286 375 375 LYS LYS C . n 
C 1 287 LEU 287 376 376 LEU LEU C . n 
C 1 288 THR 288 377 377 THR THR C . n 
C 1 289 PHE 289 378 378 PHE PHE C . n 
C 1 290 ARG 290 379 ?   ?   ?   C . n 
C 1 291 GLU 291 380 ?   ?   ?   C . n 
C 1 292 ASN 292 381 ?   ?   ?   C . n 
C 1 293 ALA 293 382 ?   ?   ?   C . n 
C 1 294 LYS 294 383 ?   ?   ?   C . n 
C 1 295 ALA 295 384 ?   ?   ?   C . n 
C 1 296 LYS 296 385 ?   ?   ?   C . n 
C 1 297 THR 297 386 ?   ?   ?   C . n 
C 1 298 ASP 298 387 ?   ?   ?   C . n 
C 1 299 HIS 299 388 ?   ?   ?   C . n 
C 1 300 GLY 300 389 ?   ?   ?   C . n 
C 1 301 ALA 301 390 ?   ?   ?   C . n 
C 1 302 GLU 302 391 ?   ?   ?   C . n 
C 1 303 ILE 303 392 ?   ?   ?   C . n 
C 1 304 VAL 304 393 ?   ?   ?   C . n 
C 1 305 TYR 305 394 ?   ?   ?   C . n 
C 1 306 LYS 306 395 ?   ?   ?   C . n 
C 1 307 ASP 307 396 ?   ?   ?   C . n 
C 1 308 PRO 308 397 ?   ?   ?   C . n 
C 1 309 VAL 309 398 ?   ?   ?   C . n 
C 1 310 VAL 310 399 ?   ?   ?   C . n 
C 1 311 ASP 311 400 ?   ?   ?   C . n 
C 1 312 GLY 312 401 ?   ?   ?   C . n 
C 1 313 ASP 313 402 ?   ?   ?   C . n 
C 1 314 ASP 314 403 ?   ?   ?   C . n 
C 1 315 ASP 315 404 ?   ?   ?   C . n 
C 1 316 PRO 316 405 ?   ?   ?   C . n 
C 1 317 ARG 317 406 ?   ?   ?   C . n 
C 1 318 HIS 318 407 ?   ?   ?   C . n 
C 1 319 LEU 319 408 ?   ?   ?   C . n 
C 1 320 SER 320 409 ?   ?   ?   C . n 
C 1 321 ASN 321 410 ?   ?   ?   C . n 
C 1 322 VAL 322 411 ?   ?   ?   C . n 
C 1 323 SER 323 412 ?   ?   ?   C . n 
C 1 324 SER 324 413 ?   ?   ?   C . n 
C 1 325 THR 325 414 ?   ?   ?   C . n 
C 1 326 GLY 326 415 ?   ?   ?   C . n 
C 1 327 SER 327 416 ?   ?   ?   C . n 
C 1 328 ILE 328 417 ?   ?   ?   C . n 
C 1 329 ASP 329 418 ?   ?   ?   C . n 
C 1 330 MET 330 419 ?   ?   ?   C . n 
C 1 331 VAL 331 420 ?   ?   ?   C . n 
C 1 332 ASP 332 421 ?   ?   ?   C . n 
C 1 333 SER 333 422 ?   ?   ?   C . n 
C 1 334 PRO 334 423 ?   ?   ?   C . n 
C 1 335 GLN 335 424 ?   ?   ?   C . n 
C 1 336 LEU 336 425 ?   ?   ?   C . n 
C 1 337 ALA 337 426 ?   ?   ?   C . n 
C 1 338 THR 338 427 ?   ?   ?   C . n 
C 1 339 LEU 339 428 ?   ?   ?   C . n 
C 1 340 ALA 340 429 ?   ?   ?   C . n 
C 1 341 ASP 341 430 ?   ?   ?   C . n 
C 1 342 GLU 342 431 ?   ?   ?   C . n 
C 1 343 VAL 343 432 ?   ?   ?   C . n 
C 1 344 SER 344 433 ?   ?   ?   C . n 
C 1 345 ALA 345 434 ?   ?   ?   C . n 
C 1 346 SER 346 435 ?   ?   ?   C . n 
C 1 347 LEU 347 436 ?   ?   ?   C . n 
C 1 348 ALA 348 437 ?   ?   ?   C . n 
C 1 349 LYS 349 438 ?   ?   ?   C . n 
C 1 350 GLN 350 439 ?   ?   ?   C . n 
C 1 351 GLY 351 440 ?   ?   ?   C . n 
C 1 352 LEU 352 441 ?   ?   ?   C . n 
D 1 1   MET 1   90  ?   ?   ?   D . n 
D 1 2   ALA 2   91  ?   ?   ?   D . n 
D 1 3   GLU 3   92  ?   ?   ?   D . n 
D 1 4   PRO 4   93  ?   ?   ?   D . n 
D 1 5   ARG 5   94  ?   ?   ?   D . n 
D 1 6   GLN 6   95  ?   ?   ?   D . n 
D 1 7   GLU 7   96  ?   ?   ?   D . n 
D 1 8   PHE 8   97  ?   ?   ?   D . n 
D 1 9   GLU 9   98  ?   ?   ?   D . n 
D 1 10  VAL 10  99  ?   ?   ?   D . n 
D 1 11  MET 11  100 ?   ?   ?   D . n 
D 1 12  GLU 12  101 ?   ?   ?   D . n 
D 1 13  ASP 13  102 ?   ?   ?   D . n 
D 1 14  HIS 14  103 ?   ?   ?   D . n 
D 1 15  ALA 15  104 ?   ?   ?   D . n 
D 1 16  GLY 16  105 ?   ?   ?   D . n 
D 1 17  THR 17  106 ?   ?   ?   D . n 
D 1 18  TYR 18  107 ?   ?   ?   D . n 
D 1 19  GLY 19  108 ?   ?   ?   D . n 
D 1 20  LEU 20  109 ?   ?   ?   D . n 
D 1 21  GLY 21  110 ?   ?   ?   D . n 
D 1 22  ASP 22  111 ?   ?   ?   D . n 
D 1 23  ARG 23  112 ?   ?   ?   D . n 
D 1 24  LYS 24  113 ?   ?   ?   D . n 
D 1 25  ASP 25  114 ?   ?   ?   D . n 
D 1 26  GLN 26  115 ?   ?   ?   D . n 
D 1 27  GLY 27  116 ?   ?   ?   D . n 
D 1 28  GLY 28  117 ?   ?   ?   D . n 
D 1 29  TYR 29  118 ?   ?   ?   D . n 
D 1 30  THR 30  119 ?   ?   ?   D . n 
D 1 31  MET 31  120 ?   ?   ?   D . n 
D 1 32  HIS 32  121 ?   ?   ?   D . n 
D 1 33  GLN 33  122 ?   ?   ?   D . n 
D 1 34  ASP 34  123 ?   ?   ?   D . n 
D 1 35  GLN 35  124 ?   ?   ?   D . n 
D 1 36  GLU 36  125 ?   ?   ?   D . n 
D 1 37  GLY 37  126 ?   ?   ?   D . n 
D 1 38  ASP 38  127 ?   ?   ?   D . n 
D 1 39  THR 39  128 ?   ?   ?   D . n 
D 1 40  ASP 40  129 ?   ?   ?   D . n 
D 1 41  ALA 41  130 ?   ?   ?   D . n 
D 1 42  GLY 42  131 ?   ?   ?   D . n 
D 1 43  LEU 43  132 ?   ?   ?   D . n 
D 1 44  LYS 44  133 ?   ?   ?   D . n 
D 1 45  ALA 45  134 ?   ?   ?   D . n 
D 1 46  GLU 46  135 ?   ?   ?   D . n 
D 1 47  GLU 47  136 ?   ?   ?   D . n 
D 1 48  ALA 48  137 ?   ?   ?   D . n 
D 1 49  GLY 49  138 ?   ?   ?   D . n 
D 1 50  ILE 50  139 ?   ?   ?   D . n 
D 1 51  GLY 51  140 ?   ?   ?   D . n 
D 1 52  ASP 52  141 ?   ?   ?   D . n 
D 1 53  THR 53  142 ?   ?   ?   D . n 
D 1 54  PRO 54  143 ?   ?   ?   D . n 
D 1 55  SER 55  144 ?   ?   ?   D . n 
D 1 56  LEU 56  145 ?   ?   ?   D . n 
D 1 57  GLU 57  146 ?   ?   ?   D . n 
D 1 58  ASP 58  147 ?   ?   ?   D . n 
D 1 59  GLU 59  148 ?   ?   ?   D . n 
D 1 60  ALA 60  149 ?   ?   ?   D . n 
D 1 61  ALA 61  150 ?   ?   ?   D . n 
D 1 62  GLY 62  151 ?   ?   ?   D . n 
D 1 63  HIS 63  152 ?   ?   ?   D . n 
D 1 64  VAL 64  153 ?   ?   ?   D . n 
D 1 65  THR 65  154 ?   ?   ?   D . n 
D 1 66  GLN 66  155 ?   ?   ?   D . n 
D 1 67  ALA 67  156 ?   ?   ?   D . n 
D 1 68  ARG 68  157 ?   ?   ?   D . n 
D 1 69  MET 69  158 ?   ?   ?   D . n 
D 1 70  VAL 70  159 ?   ?   ?   D . n 
D 1 71  SER 71  160 ?   ?   ?   D . n 
D 1 72  LYS 72  161 ?   ?   ?   D . n 
D 1 73  SER 73  162 ?   ?   ?   D . n 
D 1 74  LYS 74  163 ?   ?   ?   D . n 
D 1 75  ASP 75  164 ?   ?   ?   D . n 
D 1 76  GLY 76  165 ?   ?   ?   D . n 
D 1 77  THR 77  166 ?   ?   ?   D . n 
D 1 78  GLY 78  167 ?   ?   ?   D . n 
D 1 79  SER 79  168 ?   ?   ?   D . n 
D 1 80  ASP 80  169 ?   ?   ?   D . n 
D 1 81  ASP 81  170 ?   ?   ?   D . n 
D 1 82  LYS 82  171 ?   ?   ?   D . n 
D 1 83  LYS 83  172 ?   ?   ?   D . n 
D 1 84  ALA 84  173 ?   ?   ?   D . n 
D 1 85  LYS 85  174 ?   ?   ?   D . n 
D 1 86  GLY 86  175 ?   ?   ?   D . n 
D 1 87  ALA 87  176 ?   ?   ?   D . n 
D 1 88  ASP 88  177 ?   ?   ?   D . n 
D 1 89  GLY 89  178 ?   ?   ?   D . n 
D 1 90  LYS 90  179 ?   ?   ?   D . n 
D 1 91  THR 91  180 ?   ?   ?   D . n 
D 1 92  LYS 92  181 ?   ?   ?   D . n 
D 1 93  ILE 93  182 ?   ?   ?   D . n 
D 1 94  ALA 94  183 ?   ?   ?   D . n 
D 1 95  THR 95  184 ?   ?   ?   D . n 
D 1 96  PRO 96  185 ?   ?   ?   D . n 
D 1 97  ARG 97  186 ?   ?   ?   D . n 
D 1 98  GLY 98  187 ?   ?   ?   D . n 
D 1 99  ALA 99  188 ?   ?   ?   D . n 
D 1 100 ALA 100 189 ?   ?   ?   D . n 
D 1 101 PRO 101 190 ?   ?   ?   D . n 
D 1 102 PRO 102 191 ?   ?   ?   D . n 
D 1 103 GLY 103 192 ?   ?   ?   D . n 
D 1 104 GLN 104 193 ?   ?   ?   D . n 
D 1 105 LYS 105 194 ?   ?   ?   D . n 
D 1 106 GLY 106 195 ?   ?   ?   D . n 
D 1 107 GLN 107 196 ?   ?   ?   D . n 
D 1 108 ALA 108 197 ?   ?   ?   D . n 
D 1 109 ASN 109 198 ?   ?   ?   D . n 
D 1 110 ALA 110 199 ?   ?   ?   D . n 
D 1 111 THR 111 200 ?   ?   ?   D . n 
D 1 112 ARG 112 201 ?   ?   ?   D . n 
D 1 113 ILE 113 202 ?   ?   ?   D . n 
D 1 114 PRO 114 203 ?   ?   ?   D . n 
D 1 115 ALA 115 204 ?   ?   ?   D . n 
D 1 116 LYS 116 205 ?   ?   ?   D . n 
D 1 117 THR 117 206 ?   ?   ?   D . n 
D 1 118 PRO 118 207 ?   ?   ?   D . n 
D 1 119 PRO 119 208 ?   ?   ?   D . n 
D 1 120 ALA 120 209 ?   ?   ?   D . n 
D 1 121 PRO 121 210 ?   ?   ?   D . n 
D 1 122 LYS 122 211 ?   ?   ?   D . n 
D 1 123 ASP 123 212 ?   ?   ?   D . n 
D 1 124 PRO 124 213 ?   ?   ?   D . n 
D 1 125 PRO 125 214 ?   ?   ?   D . n 
D 1 126 SER 126 215 ?   ?   ?   D . n 
D 1 127 SER 127 216 ?   ?   ?   D . n 
D 1 128 GLY 128 217 ?   ?   ?   D . n 
D 1 129 GLU 129 218 ?   ?   ?   D . n 
D 1 130 PRO 130 219 ?   ?   ?   D . n 
D 1 131 PRO 131 220 ?   ?   ?   D . n 
D 1 132 LYS 132 221 ?   ?   ?   D . n 
D 1 133 SER 133 222 ?   ?   ?   D . n 
D 1 134 GLY 134 223 ?   ?   ?   D . n 
D 1 135 ASP 135 224 ?   ?   ?   D . n 
D 1 136 ARG 136 225 ?   ?   ?   D . n 
D 1 137 SER 137 226 ?   ?   ?   D . n 
D 1 138 GLY 138 227 ?   ?   ?   D . n 
D 1 139 TYR 139 228 ?   ?   ?   D . n 
D 1 140 SER 140 229 ?   ?   ?   D . n 
D 1 141 SER 141 230 ?   ?   ?   D . n 
D 1 142 PRO 142 231 ?   ?   ?   D . n 
D 1 143 GLY 143 232 ?   ?   ?   D . n 
D 1 144 ASP 144 233 ?   ?   ?   D . n 
D 1 145 PRO 145 234 ?   ?   ?   D . n 
D 1 146 GLY 146 235 ?   ?   ?   D . n 
D 1 147 ASP 147 236 ?   ?   ?   D . n 
D 1 148 PRO 148 237 ?   ?   ?   D . n 
D 1 149 GLY 149 238 ?   ?   ?   D . n 
D 1 150 SER 150 239 ?   ?   ?   D . n 
D 1 151 ARG 151 240 ?   ?   ?   D . n 
D 1 152 SER 152 241 ?   ?   ?   D . n 
D 1 153 ARG 153 242 ?   ?   ?   D . n 
D 1 154 ASP 154 243 ?   ?   ?   D . n 
D 1 155 PRO 155 244 ?   ?   ?   D . n 
D 1 156 ASP 156 245 ?   ?   ?   D . n 
D 1 157 LEU 157 246 ?   ?   ?   D . n 
D 1 158 PRO 158 247 ?   ?   ?   D . n 
D 1 159 ASP 159 248 ?   ?   ?   D . n 
D 1 160 PRO 160 249 ?   ?   ?   D . n 
D 1 161 PRO 161 250 ?   ?   ?   D . n 
D 1 162 THR 162 251 ?   ?   ?   D . n 
D 1 163 ARG 163 252 ?   ?   ?   D . n 
D 1 164 GLU 164 253 ?   ?   ?   D . n 
D 1 165 PRO 165 254 ?   ?   ?   D . n 
D 1 166 LYS 166 255 ?   ?   ?   D . n 
D 1 167 LYS 167 256 ?   ?   ?   D . n 
D 1 168 VAL 168 257 ?   ?   ?   D . n 
D 1 169 ALA 169 258 ?   ?   ?   D . n 
D 1 170 VAL 170 259 ?   ?   ?   D . n 
D 1 171 VAL 171 260 ?   ?   ?   D . n 
D 1 172 ARG 172 261 ?   ?   ?   D . n 
D 1 173 ASP 173 262 ?   ?   ?   D . n 
D 1 174 PRO 174 263 ?   ?   ?   D . n 
D 1 175 PRO 175 264 ?   ?   ?   D . n 
D 1 176 LYS 176 265 ?   ?   ?   D . n 
D 1 177 ASP 177 266 ?   ?   ?   D . n 
D 1 178 PRO 178 267 ?   ?   ?   D . n 
D 1 179 SER 179 268 ?   ?   ?   D . n 
D 1 180 SER 180 269 ?   ?   ?   D . n 
D 1 181 ALA 181 270 ?   ?   ?   D . n 
D 1 182 LYS 182 271 ?   ?   ?   D . n 
D 1 183 SER 183 272 ?   ?   ?   D . n 
D 1 184 ARG 184 273 ?   ?   ?   D . n 
D 1 185 LEU 185 274 ?   ?   ?   D . n 
D 1 186 GLN 186 275 ?   ?   ?   D . n 
D 1 187 THR 187 276 ?   ?   ?   D . n 
D 1 188 ALA 188 277 ?   ?   ?   D . n 
D 1 189 PRO 189 278 ?   ?   ?   D . n 
D 1 190 VAL 190 279 ?   ?   ?   D . n 
D 1 191 PRO 191 280 ?   ?   ?   D . n 
D 1 192 MET 192 281 ?   ?   ?   D . n 
D 1 193 PRO 193 282 ?   ?   ?   D . n 
D 1 194 ASP 194 283 ?   ?   ?   D . n 
D 1 195 LEU 195 284 ?   ?   ?   D . n 
D 1 196 LYS 196 285 ?   ?   ?   D . n 
D 1 197 ASN 197 286 ?   ?   ?   D . n 
D 1 198 VAL 198 287 ?   ?   ?   D . n 
D 1 199 LYS 199 288 ?   ?   ?   D . n 
D 1 200 SER 200 289 ?   ?   ?   D . n 
D 1 201 LYS 201 290 ?   ?   ?   D . n 
D 1 202 ILE 202 291 ?   ?   ?   D . n 
D 1 203 GLY 203 292 ?   ?   ?   D . n 
D 1 204 SER 204 293 ?   ?   ?   D . n 
D 1 205 THR 205 294 ?   ?   ?   D . n 
D 1 206 GLU 206 295 ?   ?   ?   D . n 
D 1 207 ASN 207 296 ?   ?   ?   D . n 
D 1 208 LEU 208 297 ?   ?   ?   D . n 
D 1 209 LYS 209 298 ?   ?   ?   D . n 
D 1 210 HIS 210 299 ?   ?   ?   D . n 
D 1 211 GLN 211 300 ?   ?   ?   D . n 
D 1 212 PRO 212 301 ?   ?   ?   D . n 
D 1 213 GLY 213 302 ?   ?   ?   D . n 
D 1 214 GLY 214 303 ?   ?   ?   D . n 
D 1 215 GLY 215 304 ?   ?   ?   D . n 
D 1 216 LYS 216 305 ?   ?   ?   D . n 
D 1 217 VAL 217 306 ?   ?   ?   D . n 
D 1 218 GLN 218 307 307 GLN GLN D . n 
D 1 219 ILE 219 308 308 ILE ILE D . n 
D 1 220 VAL 220 309 309 VAL VAL D . n 
D 1 221 TYR 221 310 310 TYR TYR D . n 
D 1 222 LYS 222 311 311 LYS LYS D . n 
D 1 223 PRO 223 312 312 PRO PRO D . n 
D 1 224 VAL 224 313 313 VAL VAL D . n 
D 1 225 ASP 225 314 314 ASP ASP D . n 
D 1 226 LEU 226 315 315 LEU LEU D . n 
D 1 227 SER 227 316 316 SER SER D . n 
D 1 228 LYS 228 317 317 LYS LYS D . n 
D 1 229 VAL 229 318 318 VAL VAL D . n 
D 1 230 THR 230 319 319 THR THR D . n 
D 1 231 SER 231 320 320 SER SER D . n 
D 1 232 LYS 232 321 321 LYS LYS D . n 
D 1 233 CYS 233 322 322 CYS CYS D . n 
D 1 234 GLY 234 323 323 GLY GLY D . n 
D 1 235 SER 235 324 324 SER SER D . n 
D 1 236 LEU 236 325 325 LEU LEU D . n 
D 1 237 GLY 237 326 326 GLY GLY D . n 
D 1 238 ASN 238 327 327 ASN ASN D . n 
D 1 239 ILE 239 328 328 ILE ILE D . n 
D 1 240 HIS 240 329 329 HIS HIS D . n 
D 1 241 HIS 241 330 330 HIS HIS D . n 
D 1 242 LYS 242 331 331 LYS LYS D . n 
D 1 243 PRO 243 332 332 PRO PRO D . n 
D 1 244 GLY 244 333 333 GLY GLY D . n 
D 1 245 GLY 245 334 334 GLY GLY D . n 
D 1 246 GLY 246 335 335 GLY GLY D . n 
D 1 247 GLN 247 336 336 GLN GLN D . n 
D 1 248 VAL 248 337 337 VAL VAL D . n 
D 1 249 GLU 249 338 338 GLU GLU D . n 
D 1 250 VAL 250 339 339 VAL VAL D . n 
D 1 251 LYS 251 340 340 LYS LYS D . n 
D 1 252 SER 252 341 341 SER SER D . n 
D 1 253 GLU 253 342 342 GLU GLU D . n 
D 1 254 LYS 254 343 343 LYS LYS D . n 
D 1 255 LEU 255 344 344 LEU LEU D . n 
D 1 256 ASP 256 345 345 ASP ASP D . n 
D 1 257 PHE 257 346 346 PHE PHE D . n 
D 1 258 LYS 258 347 347 LYS LYS D . n 
D 1 259 ASP 259 348 348 ASP ASP D . n 
D 1 260 ARG 260 349 349 ARG ARG D . n 
D 1 261 VAL 261 350 350 VAL VAL D . n 
D 1 262 GLN 262 351 351 GLN GLN D . n 
D 1 263 SER 263 352 352 SER SER D . n 
D 1 264 LYS 264 353 353 LYS LYS D . n 
D 1 265 ILE 265 354 354 ILE ILE D . n 
D 1 266 GLY 266 355 355 GLY GLY D . n 
D 1 267 SER 267 356 356 SER SER D . n 
D 1 268 LEU 268 357 357 LEU LEU D . n 
D 1 269 ASP 269 358 358 ASP ASP D . n 
D 1 270 ASN 270 359 359 ASN ASN D . n 
D 1 271 ILE 271 360 360 ILE ILE D . n 
D 1 272 THR 272 361 361 THR THR D . n 
D 1 273 HIS 273 362 362 HIS HIS D . n 
D 1 274 VAL 274 363 363 VAL VAL D . n 
D 1 275 PRO 275 364 364 PRO PRO D . n 
D 1 276 GLY 276 365 365 GLY GLY D . n 
D 1 277 GLY 277 366 366 GLY GLY D . n 
D 1 278 GLY 278 367 367 GLY GLY D . n 
D 1 279 ASN 279 368 368 ASN ASN D . n 
D 1 280 LYS 280 369 369 LYS LYS D . n 
D 1 281 LYS 281 370 370 LYS LYS D . n 
D 1 282 ILE 282 371 371 ILE ILE D . n 
D 1 283 GLU 283 372 372 GLU GLU D . n 
D 1 284 THR 284 373 373 THR THR D . n 
D 1 285 HIS 285 374 374 HIS HIS D . n 
D 1 286 LYS 286 375 375 LYS LYS D . n 
D 1 287 LEU 287 376 376 LEU LEU D . n 
D 1 288 THR 288 377 377 THR THR D . n 
D 1 289 PHE 289 378 378 PHE PHE D . n 
D 1 290 ARG 290 379 ?   ?   ?   D . n 
D 1 291 GLU 291 380 ?   ?   ?   D . n 
D 1 292 ASN 292 381 ?   ?   ?   D . n 
D 1 293 ALA 293 382 ?   ?   ?   D . n 
D 1 294 LYS 294 383 ?   ?   ?   D . n 
D 1 295 ALA 295 384 ?   ?   ?   D . n 
D 1 296 LYS 296 385 ?   ?   ?   D . n 
D 1 297 THR 297 386 ?   ?   ?   D . n 
D 1 298 ASP 298 387 ?   ?   ?   D . n 
D 1 299 HIS 299 388 ?   ?   ?   D . n 
D 1 300 GLY 300 389 ?   ?   ?   D . n 
D 1 301 ALA 301 390 ?   ?   ?   D . n 
D 1 302 GLU 302 391 ?   ?   ?   D . n 
D 1 303 ILE 303 392 ?   ?   ?   D . n 
D 1 304 VAL 304 393 ?   ?   ?   D . n 
D 1 305 TYR 305 394 ?   ?   ?   D . n 
D 1 306 LYS 306 395 ?   ?   ?   D . n 
D 1 307 ASP 307 396 ?   ?   ?   D . n 
D 1 308 PRO 308 397 ?   ?   ?   D . n 
D 1 309 VAL 309 398 ?   ?   ?   D . n 
D 1 310 VAL 310 399 ?   ?   ?   D . n 
D 1 311 ASP 311 400 ?   ?   ?   D . n 
D 1 312 GLY 312 401 ?   ?   ?   D . n 
D 1 313 ASP 313 402 ?   ?   ?   D . n 
D 1 314 ASP 314 403 ?   ?   ?   D . n 
D 1 315 ASP 315 404 ?   ?   ?   D . n 
D 1 316 PRO 316 405 ?   ?   ?   D . n 
D 1 317 ARG 317 406 ?   ?   ?   D . n 
D 1 318 HIS 318 407 ?   ?   ?   D . n 
D 1 319 LEU 319 408 ?   ?   ?   D . n 
D 1 320 SER 320 409 ?   ?   ?   D . n 
D 1 321 ASN 321 410 ?   ?   ?   D . n 
D 1 322 VAL 322 411 ?   ?   ?   D . n 
D 1 323 SER 323 412 ?   ?   ?   D . n 
D 1 324 SER 324 413 ?   ?   ?   D . n 
D 1 325 THR 325 414 ?   ?   ?   D . n 
D 1 326 GLY 326 415 ?   ?   ?   D . n 
D 1 327 SER 327 416 ?   ?   ?   D . n 
D 1 328 ILE 328 417 ?   ?   ?   D . n 
D 1 329 ASP 329 418 ?   ?   ?   D . n 
D 1 330 MET 330 419 ?   ?   ?   D . n 
D 1 331 VAL 331 420 ?   ?   ?   D . n 
D 1 332 ASP 332 421 ?   ?   ?   D . n 
D 1 333 SER 333 422 ?   ?   ?   D . n 
D 1 334 PRO 334 423 ?   ?   ?   D . n 
D 1 335 GLN 335 424 ?   ?   ?   D . n 
D 1 336 LEU 336 425 ?   ?   ?   D . n 
D 1 337 ALA 337 426 ?   ?   ?   D . n 
D 1 338 THR 338 427 ?   ?   ?   D . n 
D 1 339 LEU 339 428 ?   ?   ?   D . n 
D 1 340 ALA 340 429 ?   ?   ?   D . n 
D 1 341 ASP 341 430 ?   ?   ?   D . n 
D 1 342 GLU 342 431 ?   ?   ?   D . n 
D 1 343 VAL 343 432 ?   ?   ?   D . n 
D 1 344 SER 344 433 ?   ?   ?   D . n 
D 1 345 ALA 345 434 ?   ?   ?   D . n 
D 1 346 SER 346 435 ?   ?   ?   D . n 
D 1 347 LEU 347 436 ?   ?   ?   D . n 
D 1 348 ALA 348 437 ?   ?   ?   D . n 
D 1 349 LYS 349 438 ?   ?   ?   D . n 
D 1 350 GLN 350 439 ?   ?   ?   D . n 
D 1 351 GLY 351 440 ?   ?   ?   D . n 
D 1 352 LEU 352 441 ?   ?   ?   D . n 
E 1 1   MET 1   90  ?   ?   ?   E . n 
E 1 2   ALA 2   91  ?   ?   ?   E . n 
E 1 3   GLU 3   92  ?   ?   ?   E . n 
E 1 4   PRO 4   93  ?   ?   ?   E . n 
E 1 5   ARG 5   94  ?   ?   ?   E . n 
E 1 6   GLN 6   95  ?   ?   ?   E . n 
E 1 7   GLU 7   96  ?   ?   ?   E . n 
E 1 8   PHE 8   97  ?   ?   ?   E . n 
E 1 9   GLU 9   98  ?   ?   ?   E . n 
E 1 10  VAL 10  99  ?   ?   ?   E . n 
E 1 11  MET 11  100 ?   ?   ?   E . n 
E 1 12  GLU 12  101 ?   ?   ?   E . n 
E 1 13  ASP 13  102 ?   ?   ?   E . n 
E 1 14  HIS 14  103 ?   ?   ?   E . n 
E 1 15  ALA 15  104 ?   ?   ?   E . n 
E 1 16  GLY 16  105 ?   ?   ?   E . n 
E 1 17  THR 17  106 ?   ?   ?   E . n 
E 1 18  TYR 18  107 ?   ?   ?   E . n 
E 1 19  GLY 19  108 ?   ?   ?   E . n 
E 1 20  LEU 20  109 ?   ?   ?   E . n 
E 1 21  GLY 21  110 ?   ?   ?   E . n 
E 1 22  ASP 22  111 ?   ?   ?   E . n 
E 1 23  ARG 23  112 ?   ?   ?   E . n 
E 1 24  LYS 24  113 ?   ?   ?   E . n 
E 1 25  ASP 25  114 ?   ?   ?   E . n 
E 1 26  GLN 26  115 ?   ?   ?   E . n 
E 1 27  GLY 27  116 ?   ?   ?   E . n 
E 1 28  GLY 28  117 ?   ?   ?   E . n 
E 1 29  TYR 29  118 ?   ?   ?   E . n 
E 1 30  THR 30  119 ?   ?   ?   E . n 
E 1 31  MET 31  120 ?   ?   ?   E . n 
E 1 32  HIS 32  121 ?   ?   ?   E . n 
E 1 33  GLN 33  122 ?   ?   ?   E . n 
E 1 34  ASP 34  123 ?   ?   ?   E . n 
E 1 35  GLN 35  124 ?   ?   ?   E . n 
E 1 36  GLU 36  125 ?   ?   ?   E . n 
E 1 37  GLY 37  126 ?   ?   ?   E . n 
E 1 38  ASP 38  127 ?   ?   ?   E . n 
E 1 39  THR 39  128 ?   ?   ?   E . n 
E 1 40  ASP 40  129 ?   ?   ?   E . n 
E 1 41  ALA 41  130 ?   ?   ?   E . n 
E 1 42  GLY 42  131 ?   ?   ?   E . n 
E 1 43  LEU 43  132 ?   ?   ?   E . n 
E 1 44  LYS 44  133 ?   ?   ?   E . n 
E 1 45  ALA 45  134 ?   ?   ?   E . n 
E 1 46  GLU 46  135 ?   ?   ?   E . n 
E 1 47  GLU 47  136 ?   ?   ?   E . n 
E 1 48  ALA 48  137 ?   ?   ?   E . n 
E 1 49  GLY 49  138 ?   ?   ?   E . n 
E 1 50  ILE 50  139 ?   ?   ?   E . n 
E 1 51  GLY 51  140 ?   ?   ?   E . n 
E 1 52  ASP 52  141 ?   ?   ?   E . n 
E 1 53  THR 53  142 ?   ?   ?   E . n 
E 1 54  PRO 54  143 ?   ?   ?   E . n 
E 1 55  SER 55  144 ?   ?   ?   E . n 
E 1 56  LEU 56  145 ?   ?   ?   E . n 
E 1 57  GLU 57  146 ?   ?   ?   E . n 
E 1 58  ASP 58  147 ?   ?   ?   E . n 
E 1 59  GLU 59  148 ?   ?   ?   E . n 
E 1 60  ALA 60  149 ?   ?   ?   E . n 
E 1 61  ALA 61  150 ?   ?   ?   E . n 
E 1 62  GLY 62  151 ?   ?   ?   E . n 
E 1 63  HIS 63  152 ?   ?   ?   E . n 
E 1 64  VAL 64  153 ?   ?   ?   E . n 
E 1 65  THR 65  154 ?   ?   ?   E . n 
E 1 66  GLN 66  155 ?   ?   ?   E . n 
E 1 67  ALA 67  156 ?   ?   ?   E . n 
E 1 68  ARG 68  157 ?   ?   ?   E . n 
E 1 69  MET 69  158 ?   ?   ?   E . n 
E 1 70  VAL 70  159 ?   ?   ?   E . n 
E 1 71  SER 71  160 ?   ?   ?   E . n 
E 1 72  LYS 72  161 ?   ?   ?   E . n 
E 1 73  SER 73  162 ?   ?   ?   E . n 
E 1 74  LYS 74  163 ?   ?   ?   E . n 
E 1 75  ASP 75  164 ?   ?   ?   E . n 
E 1 76  GLY 76  165 ?   ?   ?   E . n 
E 1 77  THR 77  166 ?   ?   ?   E . n 
E 1 78  GLY 78  167 ?   ?   ?   E . n 
E 1 79  SER 79  168 ?   ?   ?   E . n 
E 1 80  ASP 80  169 ?   ?   ?   E . n 
E 1 81  ASP 81  170 ?   ?   ?   E . n 
E 1 82  LYS 82  171 ?   ?   ?   E . n 
E 1 83  LYS 83  172 ?   ?   ?   E . n 
E 1 84  ALA 84  173 ?   ?   ?   E . n 
E 1 85  LYS 85  174 ?   ?   ?   E . n 
E 1 86  GLY 86  175 ?   ?   ?   E . n 
E 1 87  ALA 87  176 ?   ?   ?   E . n 
E 1 88  ASP 88  177 ?   ?   ?   E . n 
E 1 89  GLY 89  178 ?   ?   ?   E . n 
E 1 90  LYS 90  179 ?   ?   ?   E . n 
E 1 91  THR 91  180 ?   ?   ?   E . n 
E 1 92  LYS 92  181 ?   ?   ?   E . n 
E 1 93  ILE 93  182 ?   ?   ?   E . n 
E 1 94  ALA 94  183 ?   ?   ?   E . n 
E 1 95  THR 95  184 ?   ?   ?   E . n 
E 1 96  PRO 96  185 ?   ?   ?   E . n 
E 1 97  ARG 97  186 ?   ?   ?   E . n 
E 1 98  GLY 98  187 ?   ?   ?   E . n 
E 1 99  ALA 99  188 ?   ?   ?   E . n 
E 1 100 ALA 100 189 ?   ?   ?   E . n 
E 1 101 PRO 101 190 ?   ?   ?   E . n 
E 1 102 PRO 102 191 ?   ?   ?   E . n 
E 1 103 GLY 103 192 ?   ?   ?   E . n 
E 1 104 GLN 104 193 ?   ?   ?   E . n 
E 1 105 LYS 105 194 ?   ?   ?   E . n 
E 1 106 GLY 106 195 ?   ?   ?   E . n 
E 1 107 GLN 107 196 ?   ?   ?   E . n 
E 1 108 ALA 108 197 ?   ?   ?   E . n 
E 1 109 ASN 109 198 ?   ?   ?   E . n 
E 1 110 ALA 110 199 ?   ?   ?   E . n 
E 1 111 THR 111 200 ?   ?   ?   E . n 
E 1 112 ARG 112 201 ?   ?   ?   E . n 
E 1 113 ILE 113 202 ?   ?   ?   E . n 
E 1 114 PRO 114 203 ?   ?   ?   E . n 
E 1 115 ALA 115 204 ?   ?   ?   E . n 
E 1 116 LYS 116 205 ?   ?   ?   E . n 
E 1 117 THR 117 206 ?   ?   ?   E . n 
E 1 118 PRO 118 207 ?   ?   ?   E . n 
E 1 119 PRO 119 208 ?   ?   ?   E . n 
E 1 120 ALA 120 209 ?   ?   ?   E . n 
E 1 121 PRO 121 210 ?   ?   ?   E . n 
E 1 122 LYS 122 211 ?   ?   ?   E . n 
E 1 123 ASP 123 212 ?   ?   ?   E . n 
E 1 124 PRO 124 213 ?   ?   ?   E . n 
E 1 125 PRO 125 214 ?   ?   ?   E . n 
E 1 126 SER 126 215 ?   ?   ?   E . n 
E 1 127 SER 127 216 ?   ?   ?   E . n 
E 1 128 GLY 128 217 ?   ?   ?   E . n 
E 1 129 GLU 129 218 ?   ?   ?   E . n 
E 1 130 PRO 130 219 ?   ?   ?   E . n 
E 1 131 PRO 131 220 ?   ?   ?   E . n 
E 1 132 LYS 132 221 ?   ?   ?   E . n 
E 1 133 SER 133 222 ?   ?   ?   E . n 
E 1 134 GLY 134 223 ?   ?   ?   E . n 
E 1 135 ASP 135 224 ?   ?   ?   E . n 
E 1 136 ARG 136 225 ?   ?   ?   E . n 
E 1 137 SER 137 226 ?   ?   ?   E . n 
E 1 138 GLY 138 227 ?   ?   ?   E . n 
E 1 139 TYR 139 228 ?   ?   ?   E . n 
E 1 140 SER 140 229 ?   ?   ?   E . n 
E 1 141 SER 141 230 ?   ?   ?   E . n 
E 1 142 PRO 142 231 ?   ?   ?   E . n 
E 1 143 GLY 143 232 ?   ?   ?   E . n 
E 1 144 ASP 144 233 ?   ?   ?   E . n 
E 1 145 PRO 145 234 ?   ?   ?   E . n 
E 1 146 GLY 146 235 ?   ?   ?   E . n 
E 1 147 ASP 147 236 ?   ?   ?   E . n 
E 1 148 PRO 148 237 ?   ?   ?   E . n 
E 1 149 GLY 149 238 ?   ?   ?   E . n 
E 1 150 SER 150 239 ?   ?   ?   E . n 
E 1 151 ARG 151 240 ?   ?   ?   E . n 
E 1 152 SER 152 241 ?   ?   ?   E . n 
E 1 153 ARG 153 242 ?   ?   ?   E . n 
E 1 154 ASP 154 243 ?   ?   ?   E . n 
E 1 155 PRO 155 244 ?   ?   ?   E . n 
E 1 156 ASP 156 245 ?   ?   ?   E . n 
E 1 157 LEU 157 246 ?   ?   ?   E . n 
E 1 158 PRO 158 247 ?   ?   ?   E . n 
E 1 159 ASP 159 248 ?   ?   ?   E . n 
E 1 160 PRO 160 249 ?   ?   ?   E . n 
E 1 161 PRO 161 250 ?   ?   ?   E . n 
E 1 162 THR 162 251 ?   ?   ?   E . n 
E 1 163 ARG 163 252 ?   ?   ?   E . n 
E 1 164 GLU 164 253 ?   ?   ?   E . n 
E 1 165 PRO 165 254 ?   ?   ?   E . n 
E 1 166 LYS 166 255 ?   ?   ?   E . n 
E 1 167 LYS 167 256 ?   ?   ?   E . n 
E 1 168 VAL 168 257 ?   ?   ?   E . n 
E 1 169 ALA 169 258 ?   ?   ?   E . n 
E 1 170 VAL 170 259 ?   ?   ?   E . n 
E 1 171 VAL 171 260 ?   ?   ?   E . n 
E 1 172 ARG 172 261 ?   ?   ?   E . n 
E 1 173 ASP 173 262 ?   ?   ?   E . n 
E 1 174 PRO 174 263 ?   ?   ?   E . n 
E 1 175 PRO 175 264 ?   ?   ?   E . n 
E 1 176 LYS 176 265 ?   ?   ?   E . n 
E 1 177 ASP 177 266 ?   ?   ?   E . n 
E 1 178 PRO 178 267 ?   ?   ?   E . n 
E 1 179 SER 179 268 ?   ?   ?   E . n 
E 1 180 SER 180 269 ?   ?   ?   E . n 
E 1 181 ALA 181 270 ?   ?   ?   E . n 
E 1 182 LYS 182 271 ?   ?   ?   E . n 
E 1 183 SER 183 272 ?   ?   ?   E . n 
E 1 184 ARG 184 273 ?   ?   ?   E . n 
E 1 185 LEU 185 274 ?   ?   ?   E . n 
E 1 186 GLN 186 275 ?   ?   ?   E . n 
E 1 187 THR 187 276 ?   ?   ?   E . n 
E 1 188 ALA 188 277 ?   ?   ?   E . n 
E 1 189 PRO 189 278 ?   ?   ?   E . n 
E 1 190 VAL 190 279 ?   ?   ?   E . n 
E 1 191 PRO 191 280 ?   ?   ?   E . n 
E 1 192 MET 192 281 ?   ?   ?   E . n 
E 1 193 PRO 193 282 ?   ?   ?   E . n 
E 1 194 ASP 194 283 ?   ?   ?   E . n 
E 1 195 LEU 195 284 ?   ?   ?   E . n 
E 1 196 LYS 196 285 ?   ?   ?   E . n 
E 1 197 ASN 197 286 ?   ?   ?   E . n 
E 1 198 VAL 198 287 ?   ?   ?   E . n 
E 1 199 LYS 199 288 ?   ?   ?   E . n 
E 1 200 SER 200 289 ?   ?   ?   E . n 
E 1 201 LYS 201 290 ?   ?   ?   E . n 
E 1 202 ILE 202 291 ?   ?   ?   E . n 
E 1 203 GLY 203 292 ?   ?   ?   E . n 
E 1 204 SER 204 293 ?   ?   ?   E . n 
E 1 205 THR 205 294 ?   ?   ?   E . n 
E 1 206 GLU 206 295 ?   ?   ?   E . n 
E 1 207 ASN 207 296 ?   ?   ?   E . n 
E 1 208 LEU 208 297 ?   ?   ?   E . n 
E 1 209 LYS 209 298 ?   ?   ?   E . n 
E 1 210 HIS 210 299 ?   ?   ?   E . n 
E 1 211 GLN 211 300 ?   ?   ?   E . n 
E 1 212 PRO 212 301 ?   ?   ?   E . n 
E 1 213 GLY 213 302 ?   ?   ?   E . n 
E 1 214 GLY 214 303 ?   ?   ?   E . n 
E 1 215 GLY 215 304 ?   ?   ?   E . n 
E 1 216 LYS 216 305 ?   ?   ?   E . n 
E 1 217 VAL 217 306 ?   ?   ?   E . n 
E 1 218 GLN 218 307 307 GLN GLN E . n 
E 1 219 ILE 219 308 308 ILE ILE E . n 
E 1 220 VAL 220 309 309 VAL VAL E . n 
E 1 221 TYR 221 310 310 TYR TYR E . n 
E 1 222 LYS 222 311 311 LYS LYS E . n 
E 1 223 PRO 223 312 312 PRO PRO E . n 
E 1 224 VAL 224 313 313 VAL VAL E . n 
E 1 225 ASP 225 314 314 ASP ASP E . n 
E 1 226 LEU 226 315 315 LEU LEU E . n 
E 1 227 SER 227 316 316 SER SER E . n 
E 1 228 LYS 228 317 317 LYS LYS E . n 
E 1 229 VAL 229 318 318 VAL VAL E . n 
E 1 230 THR 230 319 319 THR THR E . n 
E 1 231 SER 231 320 320 SER SER E . n 
E 1 232 LYS 232 321 321 LYS LYS E . n 
E 1 233 CYS 233 322 322 CYS CYS E . n 
E 1 234 GLY 234 323 323 GLY GLY E . n 
E 1 235 SER 235 324 324 SER SER E . n 
E 1 236 LEU 236 325 325 LEU LEU E . n 
E 1 237 GLY 237 326 326 GLY GLY E . n 
E 1 238 ASN 238 327 327 ASN ASN E . n 
E 1 239 ILE 239 328 328 ILE ILE E . n 
E 1 240 HIS 240 329 329 HIS HIS E . n 
E 1 241 HIS 241 330 330 HIS HIS E . n 
E 1 242 LYS 242 331 331 LYS LYS E . n 
E 1 243 PRO 243 332 332 PRO PRO E . n 
E 1 244 GLY 244 333 333 GLY GLY E . n 
E 1 245 GLY 245 334 334 GLY GLY E . n 
E 1 246 GLY 246 335 335 GLY GLY E . n 
E 1 247 GLN 247 336 336 GLN GLN E . n 
E 1 248 VAL 248 337 337 VAL VAL E . n 
E 1 249 GLU 249 338 338 GLU GLU E . n 
E 1 250 VAL 250 339 339 VAL VAL E . n 
E 1 251 LYS 251 340 340 LYS LYS E . n 
E 1 252 SER 252 341 341 SER SER E . n 
E 1 253 GLU 253 342 342 GLU GLU E . n 
E 1 254 LYS 254 343 343 LYS LYS E . n 
E 1 255 LEU 255 344 344 LEU LEU E . n 
E 1 256 ASP 256 345 345 ASP ASP E . n 
E 1 257 PHE 257 346 346 PHE PHE E . n 
E 1 258 LYS 258 347 347 LYS LYS E . n 
E 1 259 ASP 259 348 348 ASP ASP E . n 
E 1 260 ARG 260 349 349 ARG ARG E . n 
E 1 261 VAL 261 350 350 VAL VAL E . n 
E 1 262 GLN 262 351 351 GLN GLN E . n 
E 1 263 SER 263 352 352 SER SER E . n 
E 1 264 LYS 264 353 353 LYS LYS E . n 
E 1 265 ILE 265 354 354 ILE ILE E . n 
E 1 266 GLY 266 355 355 GLY GLY E . n 
E 1 267 SER 267 356 356 SER SER E . n 
E 1 268 LEU 268 357 357 LEU LEU E . n 
E 1 269 ASP 269 358 358 ASP ASP E . n 
E 1 270 ASN 270 359 359 ASN ASN E . n 
E 1 271 ILE 271 360 360 ILE ILE E . n 
E 1 272 THR 272 361 361 THR THR E . n 
E 1 273 HIS 273 362 362 HIS HIS E . n 
E 1 274 VAL 274 363 363 VAL VAL E . n 
E 1 275 PRO 275 364 364 PRO PRO E . n 
E 1 276 GLY 276 365 365 GLY GLY E . n 
E 1 277 GLY 277 366 366 GLY GLY E . n 
E 1 278 GLY 278 367 367 GLY GLY E . n 
E 1 279 ASN 279 368 368 ASN ASN E . n 
E 1 280 LYS 280 369 369 LYS LYS E . n 
E 1 281 LYS 281 370 370 LYS LYS E . n 
E 1 282 ILE 282 371 371 ILE ILE E . n 
E 1 283 GLU 283 372 372 GLU GLU E . n 
E 1 284 THR 284 373 373 THR THR E . n 
E 1 285 HIS 285 374 374 HIS HIS E . n 
E 1 286 LYS 286 375 375 LYS LYS E . n 
E 1 287 LEU 287 376 376 LEU LEU E . n 
E 1 288 THR 288 377 377 THR THR E . n 
E 1 289 PHE 289 378 378 PHE PHE E . n 
E 1 290 ARG 290 379 ?   ?   ?   E . n 
E 1 291 GLU 291 380 ?   ?   ?   E . n 
E 1 292 ASN 292 381 ?   ?   ?   E . n 
E 1 293 ALA 293 382 ?   ?   ?   E . n 
E 1 294 LYS 294 383 ?   ?   ?   E . n 
E 1 295 ALA 295 384 ?   ?   ?   E . n 
E 1 296 LYS 296 385 ?   ?   ?   E . n 
E 1 297 THR 297 386 ?   ?   ?   E . n 
E 1 298 ASP 298 387 ?   ?   ?   E . n 
E 1 299 HIS 299 388 ?   ?   ?   E . n 
E 1 300 GLY 300 389 ?   ?   ?   E . n 
E 1 301 ALA 301 390 ?   ?   ?   E . n 
E 1 302 GLU 302 391 ?   ?   ?   E . n 
E 1 303 ILE 303 392 ?   ?   ?   E . n 
E 1 304 VAL 304 393 ?   ?   ?   E . n 
E 1 305 TYR 305 394 ?   ?   ?   E . n 
E 1 306 LYS 306 395 ?   ?   ?   E . n 
E 1 307 ASP 307 396 ?   ?   ?   E . n 
E 1 308 PRO 308 397 ?   ?   ?   E . n 
E 1 309 VAL 309 398 ?   ?   ?   E . n 
E 1 310 VAL 310 399 ?   ?   ?   E . n 
E 1 311 ASP 311 400 ?   ?   ?   E . n 
E 1 312 GLY 312 401 ?   ?   ?   E . n 
E 1 313 ASP 313 402 ?   ?   ?   E . n 
E 1 314 ASP 314 403 ?   ?   ?   E . n 
E 1 315 ASP 315 404 ?   ?   ?   E . n 
E 1 316 PRO 316 405 ?   ?   ?   E . n 
E 1 317 ARG 317 406 ?   ?   ?   E . n 
E 1 318 HIS 318 407 ?   ?   ?   E . n 
E 1 319 LEU 319 408 ?   ?   ?   E . n 
E 1 320 SER 320 409 ?   ?   ?   E . n 
E 1 321 ASN 321 410 ?   ?   ?   E . n 
E 1 322 VAL 322 411 ?   ?   ?   E . n 
E 1 323 SER 323 412 ?   ?   ?   E . n 
E 1 324 SER 324 413 ?   ?   ?   E . n 
E 1 325 THR 325 414 ?   ?   ?   E . n 
E 1 326 GLY 326 415 ?   ?   ?   E . n 
E 1 327 SER 327 416 ?   ?   ?   E . n 
E 1 328 ILE 328 417 ?   ?   ?   E . n 
E 1 329 ASP 329 418 ?   ?   ?   E . n 
E 1 330 MET 330 419 ?   ?   ?   E . n 
E 1 331 VAL 331 420 ?   ?   ?   E . n 
E 1 332 ASP 332 421 ?   ?   ?   E . n 
E 1 333 SER 333 422 ?   ?   ?   E . n 
E 1 334 PRO 334 423 ?   ?   ?   E . n 
E 1 335 GLN 335 424 ?   ?   ?   E . n 
E 1 336 LEU 336 425 ?   ?   ?   E . n 
E 1 337 ALA 337 426 ?   ?   ?   E . n 
E 1 338 THR 338 427 ?   ?   ?   E . n 
E 1 339 LEU 339 428 ?   ?   ?   E . n 
E 1 340 ALA 340 429 ?   ?   ?   E . n 
E 1 341 ASP 341 430 ?   ?   ?   E . n 
E 1 342 GLU 342 431 ?   ?   ?   E . n 
E 1 343 VAL 343 432 ?   ?   ?   E . n 
E 1 344 SER 344 433 ?   ?   ?   E . n 
E 1 345 ALA 345 434 ?   ?   ?   E . n 
E 1 346 SER 346 435 ?   ?   ?   E . n 
E 1 347 LEU 347 436 ?   ?   ?   E . n 
E 1 348 ALA 348 437 ?   ?   ?   E . n 
E 1 349 LYS 349 438 ?   ?   ?   E . n 
E 1 350 GLN 350 439 ?   ?   ?   E . n 
E 1 351 GLY 351 440 ?   ?   ?   E . n 
E 1 352 LEU 352 441 ?   ?   ?   E . n 
F 1 1   MET 1   90  ?   ?   ?   F . n 
F 1 2   ALA 2   91  ?   ?   ?   F . n 
F 1 3   GLU 3   92  ?   ?   ?   F . n 
F 1 4   PRO 4   93  ?   ?   ?   F . n 
F 1 5   ARG 5   94  ?   ?   ?   F . n 
F 1 6   GLN 6   95  ?   ?   ?   F . n 
F 1 7   GLU 7   96  ?   ?   ?   F . n 
F 1 8   PHE 8   97  ?   ?   ?   F . n 
F 1 9   GLU 9   98  ?   ?   ?   F . n 
F 1 10  VAL 10  99  ?   ?   ?   F . n 
F 1 11  MET 11  100 ?   ?   ?   F . n 
F 1 12  GLU 12  101 ?   ?   ?   F . n 
F 1 13  ASP 13  102 ?   ?   ?   F . n 
F 1 14  HIS 14  103 ?   ?   ?   F . n 
F 1 15  ALA 15  104 ?   ?   ?   F . n 
F 1 16  GLY 16  105 ?   ?   ?   F . n 
F 1 17  THR 17  106 ?   ?   ?   F . n 
F 1 18  TYR 18  107 ?   ?   ?   F . n 
F 1 19  GLY 19  108 ?   ?   ?   F . n 
F 1 20  LEU 20  109 ?   ?   ?   F . n 
F 1 21  GLY 21  110 ?   ?   ?   F . n 
F 1 22  ASP 22  111 ?   ?   ?   F . n 
F 1 23  ARG 23  112 ?   ?   ?   F . n 
F 1 24  LYS 24  113 ?   ?   ?   F . n 
F 1 25  ASP 25  114 ?   ?   ?   F . n 
F 1 26  GLN 26  115 ?   ?   ?   F . n 
F 1 27  GLY 27  116 ?   ?   ?   F . n 
F 1 28  GLY 28  117 ?   ?   ?   F . n 
F 1 29  TYR 29  118 ?   ?   ?   F . n 
F 1 30  THR 30  119 ?   ?   ?   F . n 
F 1 31  MET 31  120 ?   ?   ?   F . n 
F 1 32  HIS 32  121 ?   ?   ?   F . n 
F 1 33  GLN 33  122 ?   ?   ?   F . n 
F 1 34  ASP 34  123 ?   ?   ?   F . n 
F 1 35  GLN 35  124 ?   ?   ?   F . n 
F 1 36  GLU 36  125 ?   ?   ?   F . n 
F 1 37  GLY 37  126 ?   ?   ?   F . n 
F 1 38  ASP 38  127 ?   ?   ?   F . n 
F 1 39  THR 39  128 ?   ?   ?   F . n 
F 1 40  ASP 40  129 ?   ?   ?   F . n 
F 1 41  ALA 41  130 ?   ?   ?   F . n 
F 1 42  GLY 42  131 ?   ?   ?   F . n 
F 1 43  LEU 43  132 ?   ?   ?   F . n 
F 1 44  LYS 44  133 ?   ?   ?   F . n 
F 1 45  ALA 45  134 ?   ?   ?   F . n 
F 1 46  GLU 46  135 ?   ?   ?   F . n 
F 1 47  GLU 47  136 ?   ?   ?   F . n 
F 1 48  ALA 48  137 ?   ?   ?   F . n 
F 1 49  GLY 49  138 ?   ?   ?   F . n 
F 1 50  ILE 50  139 ?   ?   ?   F . n 
F 1 51  GLY 51  140 ?   ?   ?   F . n 
F 1 52  ASP 52  141 ?   ?   ?   F . n 
F 1 53  THR 53  142 ?   ?   ?   F . n 
F 1 54  PRO 54  143 ?   ?   ?   F . n 
F 1 55  SER 55  144 ?   ?   ?   F . n 
F 1 56  LEU 56  145 ?   ?   ?   F . n 
F 1 57  GLU 57  146 ?   ?   ?   F . n 
F 1 58  ASP 58  147 ?   ?   ?   F . n 
F 1 59  GLU 59  148 ?   ?   ?   F . n 
F 1 60  ALA 60  149 ?   ?   ?   F . n 
F 1 61  ALA 61  150 ?   ?   ?   F . n 
F 1 62  GLY 62  151 ?   ?   ?   F . n 
F 1 63  HIS 63  152 ?   ?   ?   F . n 
F 1 64  VAL 64  153 ?   ?   ?   F . n 
F 1 65  THR 65  154 ?   ?   ?   F . n 
F 1 66  GLN 66  155 ?   ?   ?   F . n 
F 1 67  ALA 67  156 ?   ?   ?   F . n 
F 1 68  ARG 68  157 ?   ?   ?   F . n 
F 1 69  MET 69  158 ?   ?   ?   F . n 
F 1 70  VAL 70  159 ?   ?   ?   F . n 
F 1 71  SER 71  160 ?   ?   ?   F . n 
F 1 72  LYS 72  161 ?   ?   ?   F . n 
F 1 73  SER 73  162 ?   ?   ?   F . n 
F 1 74  LYS 74  163 ?   ?   ?   F . n 
F 1 75  ASP 75  164 ?   ?   ?   F . n 
F 1 76  GLY 76  165 ?   ?   ?   F . n 
F 1 77  THR 77  166 ?   ?   ?   F . n 
F 1 78  GLY 78  167 ?   ?   ?   F . n 
F 1 79  SER 79  168 ?   ?   ?   F . n 
F 1 80  ASP 80  169 ?   ?   ?   F . n 
F 1 81  ASP 81  170 ?   ?   ?   F . n 
F 1 82  LYS 82  171 ?   ?   ?   F . n 
F 1 83  LYS 83  172 ?   ?   ?   F . n 
F 1 84  ALA 84  173 ?   ?   ?   F . n 
F 1 85  LYS 85  174 ?   ?   ?   F . n 
F 1 86  GLY 86  175 ?   ?   ?   F . n 
F 1 87  ALA 87  176 ?   ?   ?   F . n 
F 1 88  ASP 88  177 ?   ?   ?   F . n 
F 1 89  GLY 89  178 ?   ?   ?   F . n 
F 1 90  LYS 90  179 ?   ?   ?   F . n 
F 1 91  THR 91  180 ?   ?   ?   F . n 
F 1 92  LYS 92  181 ?   ?   ?   F . n 
F 1 93  ILE 93  182 ?   ?   ?   F . n 
F 1 94  ALA 94  183 ?   ?   ?   F . n 
F 1 95  THR 95  184 ?   ?   ?   F . n 
F 1 96  PRO 96  185 ?   ?   ?   F . n 
F 1 97  ARG 97  186 ?   ?   ?   F . n 
F 1 98  GLY 98  187 ?   ?   ?   F . n 
F 1 99  ALA 99  188 ?   ?   ?   F . n 
F 1 100 ALA 100 189 ?   ?   ?   F . n 
F 1 101 PRO 101 190 ?   ?   ?   F . n 
F 1 102 PRO 102 191 ?   ?   ?   F . n 
F 1 103 GLY 103 192 ?   ?   ?   F . n 
F 1 104 GLN 104 193 ?   ?   ?   F . n 
F 1 105 LYS 105 194 ?   ?   ?   F . n 
F 1 106 GLY 106 195 ?   ?   ?   F . n 
F 1 107 GLN 107 196 ?   ?   ?   F . n 
F 1 108 ALA 108 197 ?   ?   ?   F . n 
F 1 109 ASN 109 198 ?   ?   ?   F . n 
F 1 110 ALA 110 199 ?   ?   ?   F . n 
F 1 111 THR 111 200 ?   ?   ?   F . n 
F 1 112 ARG 112 201 ?   ?   ?   F . n 
F 1 113 ILE 113 202 ?   ?   ?   F . n 
F 1 114 PRO 114 203 ?   ?   ?   F . n 
F 1 115 ALA 115 204 ?   ?   ?   F . n 
F 1 116 LYS 116 205 ?   ?   ?   F . n 
F 1 117 THR 117 206 ?   ?   ?   F . n 
F 1 118 PRO 118 207 ?   ?   ?   F . n 
F 1 119 PRO 119 208 ?   ?   ?   F . n 
F 1 120 ALA 120 209 ?   ?   ?   F . n 
F 1 121 PRO 121 210 ?   ?   ?   F . n 
F 1 122 LYS 122 211 ?   ?   ?   F . n 
F 1 123 ASP 123 212 ?   ?   ?   F . n 
F 1 124 PRO 124 213 ?   ?   ?   F . n 
F 1 125 PRO 125 214 ?   ?   ?   F . n 
F 1 126 SER 126 215 ?   ?   ?   F . n 
F 1 127 SER 127 216 ?   ?   ?   F . n 
F 1 128 GLY 128 217 ?   ?   ?   F . n 
F 1 129 GLU 129 218 ?   ?   ?   F . n 
F 1 130 PRO 130 219 ?   ?   ?   F . n 
F 1 131 PRO 131 220 ?   ?   ?   F . n 
F 1 132 LYS 132 221 ?   ?   ?   F . n 
F 1 133 SER 133 222 ?   ?   ?   F . n 
F 1 134 GLY 134 223 ?   ?   ?   F . n 
F 1 135 ASP 135 224 ?   ?   ?   F . n 
F 1 136 ARG 136 225 ?   ?   ?   F . n 
F 1 137 SER 137 226 ?   ?   ?   F . n 
F 1 138 GLY 138 227 ?   ?   ?   F . n 
F 1 139 TYR 139 228 ?   ?   ?   F . n 
F 1 140 SER 140 229 ?   ?   ?   F . n 
F 1 141 SER 141 230 ?   ?   ?   F . n 
F 1 142 PRO 142 231 ?   ?   ?   F . n 
F 1 143 GLY 143 232 ?   ?   ?   F . n 
F 1 144 ASP 144 233 ?   ?   ?   F . n 
F 1 145 PRO 145 234 ?   ?   ?   F . n 
F 1 146 GLY 146 235 ?   ?   ?   F . n 
F 1 147 ASP 147 236 ?   ?   ?   F . n 
F 1 148 PRO 148 237 ?   ?   ?   F . n 
F 1 149 GLY 149 238 ?   ?   ?   F . n 
F 1 150 SER 150 239 ?   ?   ?   F . n 
F 1 151 ARG 151 240 ?   ?   ?   F . n 
F 1 152 SER 152 241 ?   ?   ?   F . n 
F 1 153 ARG 153 242 ?   ?   ?   F . n 
F 1 154 ASP 154 243 ?   ?   ?   F . n 
F 1 155 PRO 155 244 ?   ?   ?   F . n 
F 1 156 ASP 156 245 ?   ?   ?   F . n 
F 1 157 LEU 157 246 ?   ?   ?   F . n 
F 1 158 PRO 158 247 ?   ?   ?   F . n 
F 1 159 ASP 159 248 ?   ?   ?   F . n 
F 1 160 PRO 160 249 ?   ?   ?   F . n 
F 1 161 PRO 161 250 ?   ?   ?   F . n 
F 1 162 THR 162 251 ?   ?   ?   F . n 
F 1 163 ARG 163 252 ?   ?   ?   F . n 
F 1 164 GLU 164 253 ?   ?   ?   F . n 
F 1 165 PRO 165 254 ?   ?   ?   F . n 
F 1 166 LYS 166 255 ?   ?   ?   F . n 
F 1 167 LYS 167 256 ?   ?   ?   F . n 
F 1 168 VAL 168 257 ?   ?   ?   F . n 
F 1 169 ALA 169 258 ?   ?   ?   F . n 
F 1 170 VAL 170 259 ?   ?   ?   F . n 
F 1 171 VAL 171 260 ?   ?   ?   F . n 
F 1 172 ARG 172 261 ?   ?   ?   F . n 
F 1 173 ASP 173 262 ?   ?   ?   F . n 
F 1 174 PRO 174 263 ?   ?   ?   F . n 
F 1 175 PRO 175 264 ?   ?   ?   F . n 
F 1 176 LYS 176 265 ?   ?   ?   F . n 
F 1 177 ASP 177 266 ?   ?   ?   F . n 
F 1 178 PRO 178 267 ?   ?   ?   F . n 
F 1 179 SER 179 268 ?   ?   ?   F . n 
F 1 180 SER 180 269 ?   ?   ?   F . n 
F 1 181 ALA 181 270 ?   ?   ?   F . n 
F 1 182 LYS 182 271 ?   ?   ?   F . n 
F 1 183 SER 183 272 ?   ?   ?   F . n 
F 1 184 ARG 184 273 ?   ?   ?   F . n 
F 1 185 LEU 185 274 ?   ?   ?   F . n 
F 1 186 GLN 186 275 ?   ?   ?   F . n 
F 1 187 THR 187 276 ?   ?   ?   F . n 
F 1 188 ALA 188 277 ?   ?   ?   F . n 
F 1 189 PRO 189 278 ?   ?   ?   F . n 
F 1 190 VAL 190 279 ?   ?   ?   F . n 
F 1 191 PRO 191 280 ?   ?   ?   F . n 
F 1 192 MET 192 281 ?   ?   ?   F . n 
F 1 193 PRO 193 282 ?   ?   ?   F . n 
F 1 194 ASP 194 283 ?   ?   ?   F . n 
F 1 195 LEU 195 284 ?   ?   ?   F . n 
F 1 196 LYS 196 285 ?   ?   ?   F . n 
F 1 197 ASN 197 286 ?   ?   ?   F . n 
F 1 198 VAL 198 287 ?   ?   ?   F . n 
F 1 199 LYS 199 288 ?   ?   ?   F . n 
F 1 200 SER 200 289 ?   ?   ?   F . n 
F 1 201 LYS 201 290 ?   ?   ?   F . n 
F 1 202 ILE 202 291 ?   ?   ?   F . n 
F 1 203 GLY 203 292 ?   ?   ?   F . n 
F 1 204 SER 204 293 ?   ?   ?   F . n 
F 1 205 THR 205 294 ?   ?   ?   F . n 
F 1 206 GLU 206 295 ?   ?   ?   F . n 
F 1 207 ASN 207 296 ?   ?   ?   F . n 
F 1 208 LEU 208 297 ?   ?   ?   F . n 
F 1 209 LYS 209 298 ?   ?   ?   F . n 
F 1 210 HIS 210 299 ?   ?   ?   F . n 
F 1 211 GLN 211 300 ?   ?   ?   F . n 
F 1 212 PRO 212 301 ?   ?   ?   F . n 
F 1 213 GLY 213 302 ?   ?   ?   F . n 
F 1 214 GLY 214 303 ?   ?   ?   F . n 
F 1 215 GLY 215 304 ?   ?   ?   F . n 
F 1 216 LYS 216 305 ?   ?   ?   F . n 
F 1 217 VAL 217 306 ?   ?   ?   F . n 
F 1 218 GLN 218 307 307 GLN GLN F . n 
F 1 219 ILE 219 308 308 ILE ILE F . n 
F 1 220 VAL 220 309 309 VAL VAL F . n 
F 1 221 TYR 221 310 310 TYR TYR F . n 
F 1 222 LYS 222 311 311 LYS LYS F . n 
F 1 223 PRO 223 312 312 PRO PRO F . n 
F 1 224 VAL 224 313 313 VAL VAL F . n 
F 1 225 ASP 225 314 314 ASP ASP F . n 
F 1 226 LEU 226 315 315 LEU LEU F . n 
F 1 227 SER 227 316 316 SER SER F . n 
F 1 228 LYS 228 317 317 LYS LYS F . n 
F 1 229 VAL 229 318 318 VAL VAL F . n 
F 1 230 THR 230 319 319 THR THR F . n 
F 1 231 SER 231 320 320 SER SER F . n 
F 1 232 LYS 232 321 321 LYS LYS F . n 
F 1 233 CYS 233 322 322 CYS CYS F . n 
F 1 234 GLY 234 323 323 GLY GLY F . n 
F 1 235 SER 235 324 324 SER SER F . n 
F 1 236 LEU 236 325 325 LEU LEU F . n 
F 1 237 GLY 237 326 326 GLY GLY F . n 
F 1 238 ASN 238 327 327 ASN ASN F . n 
F 1 239 ILE 239 328 328 ILE ILE F . n 
F 1 240 HIS 240 329 329 HIS HIS F . n 
F 1 241 HIS 241 330 330 HIS HIS F . n 
F 1 242 LYS 242 331 331 LYS LYS F . n 
F 1 243 PRO 243 332 332 PRO PRO F . n 
F 1 244 GLY 244 333 333 GLY GLY F . n 
F 1 245 GLY 245 334 334 GLY GLY F . n 
F 1 246 GLY 246 335 335 GLY GLY F . n 
F 1 247 GLN 247 336 336 GLN GLN F . n 
F 1 248 VAL 248 337 337 VAL VAL F . n 
F 1 249 GLU 249 338 338 GLU GLU F . n 
F 1 250 VAL 250 339 339 VAL VAL F . n 
F 1 251 LYS 251 340 340 LYS LYS F . n 
F 1 252 SER 252 341 341 SER SER F . n 
F 1 253 GLU 253 342 342 GLU GLU F . n 
F 1 254 LYS 254 343 343 LYS LYS F . n 
F 1 255 LEU 255 344 344 LEU LEU F . n 
F 1 256 ASP 256 345 345 ASP ASP F . n 
F 1 257 PHE 257 346 346 PHE PHE F . n 
F 1 258 LYS 258 347 347 LYS LYS F . n 
F 1 259 ASP 259 348 348 ASP ASP F . n 
F 1 260 ARG 260 349 349 ARG ARG F . n 
F 1 261 VAL 261 350 350 VAL VAL F . n 
F 1 262 GLN 262 351 351 GLN GLN F . n 
F 1 263 SER 263 352 352 SER SER F . n 
F 1 264 LYS 264 353 353 LYS LYS F . n 
F 1 265 ILE 265 354 354 ILE ILE F . n 
F 1 266 GLY 266 355 355 GLY GLY F . n 
F 1 267 SER 267 356 356 SER SER F . n 
F 1 268 LEU 268 357 357 LEU LEU F . n 
F 1 269 ASP 269 358 358 ASP ASP F . n 
F 1 270 ASN 270 359 359 ASN ASN F . n 
F 1 271 ILE 271 360 360 ILE ILE F . n 
F 1 272 THR 272 361 361 THR THR F . n 
F 1 273 HIS 273 362 362 HIS HIS F . n 
F 1 274 VAL 274 363 363 VAL VAL F . n 
F 1 275 PRO 275 364 364 PRO PRO F . n 
F 1 276 GLY 276 365 365 GLY GLY F . n 
F 1 277 GLY 277 366 366 GLY GLY F . n 
F 1 278 GLY 278 367 367 GLY GLY F . n 
F 1 279 ASN 279 368 368 ASN ASN F . n 
F 1 280 LYS 280 369 369 LYS LYS F . n 
F 1 281 LYS 281 370 370 LYS LYS F . n 
F 1 282 ILE 282 371 371 ILE ILE F . n 
F 1 283 GLU 283 372 372 GLU GLU F . n 
F 1 284 THR 284 373 373 THR THR F . n 
F 1 285 HIS 285 374 374 HIS HIS F . n 
F 1 286 LYS 286 375 375 LYS LYS F . n 
F 1 287 LEU 287 376 376 LEU LEU F . n 
F 1 288 THR 288 377 377 THR THR F . n 
F 1 289 PHE 289 378 378 PHE PHE F . n 
F 1 290 ARG 290 379 ?   ?   ?   F . n 
F 1 291 GLU 291 380 ?   ?   ?   F . n 
F 1 292 ASN 292 381 ?   ?   ?   F . n 
F 1 293 ALA 293 382 ?   ?   ?   F . n 
F 1 294 LYS 294 383 ?   ?   ?   F . n 
F 1 295 ALA 295 384 ?   ?   ?   F . n 
F 1 296 LYS 296 385 ?   ?   ?   F . n 
F 1 297 THR 297 386 ?   ?   ?   F . n 
F 1 298 ASP 298 387 ?   ?   ?   F . n 
F 1 299 HIS 299 388 ?   ?   ?   F . n 
F 1 300 GLY 300 389 ?   ?   ?   F . n 
F 1 301 ALA 301 390 ?   ?   ?   F . n 
F 1 302 GLU 302 391 ?   ?   ?   F . n 
F 1 303 ILE 303 392 ?   ?   ?   F . n 
F 1 304 VAL 304 393 ?   ?   ?   F . n 
F 1 305 TYR 305 394 ?   ?   ?   F . n 
F 1 306 LYS 306 395 ?   ?   ?   F . n 
F 1 307 ASP 307 396 ?   ?   ?   F . n 
F 1 308 PRO 308 397 ?   ?   ?   F . n 
F 1 309 VAL 309 398 ?   ?   ?   F . n 
F 1 310 VAL 310 399 ?   ?   ?   F . n 
F 1 311 ASP 311 400 ?   ?   ?   F . n 
F 1 312 GLY 312 401 ?   ?   ?   F . n 
F 1 313 ASP 313 402 ?   ?   ?   F . n 
F 1 314 ASP 314 403 ?   ?   ?   F . n 
F 1 315 ASP 315 404 ?   ?   ?   F . n 
F 1 316 PRO 316 405 ?   ?   ?   F . n 
F 1 317 ARG 317 406 ?   ?   ?   F . n 
F 1 318 HIS 318 407 ?   ?   ?   F . n 
F 1 319 LEU 319 408 ?   ?   ?   F . n 
F 1 320 SER 320 409 ?   ?   ?   F . n 
F 1 321 ASN 321 410 ?   ?   ?   F . n 
F 1 322 VAL 322 411 ?   ?   ?   F . n 
F 1 323 SER 323 412 ?   ?   ?   F . n 
F 1 324 SER 324 413 ?   ?   ?   F . n 
F 1 325 THR 325 414 ?   ?   ?   F . n 
F 1 326 GLY 326 415 ?   ?   ?   F . n 
F 1 327 SER 327 416 ?   ?   ?   F . n 
F 1 328 ILE 328 417 ?   ?   ?   F . n 
F 1 329 ASP 329 418 ?   ?   ?   F . n 
F 1 330 MET 330 419 ?   ?   ?   F . n 
F 1 331 VAL 331 420 ?   ?   ?   F . n 
F 1 332 ASP 332 421 ?   ?   ?   F . n 
F 1 333 SER 333 422 ?   ?   ?   F . n 
F 1 334 PRO 334 423 ?   ?   ?   F . n 
F 1 335 GLN 335 424 ?   ?   ?   F . n 
F 1 336 LEU 336 425 ?   ?   ?   F . n 
F 1 337 ALA 337 426 ?   ?   ?   F . n 
F 1 338 THR 338 427 ?   ?   ?   F . n 
F 1 339 LEU 339 428 ?   ?   ?   F . n 
F 1 340 ALA 340 429 ?   ?   ?   F . n 
F 1 341 ASP 341 430 ?   ?   ?   F . n 
F 1 342 GLU 342 431 ?   ?   ?   F . n 
F 1 343 VAL 343 432 ?   ?   ?   F . n 
F 1 344 SER 344 433 ?   ?   ?   F . n 
F 1 345 ALA 345 434 ?   ?   ?   F . n 
F 1 346 SER 346 435 ?   ?   ?   F . n 
F 1 347 LEU 347 436 ?   ?   ?   F . n 
F 1 348 ALA 348 437 ?   ?   ?   F . n 
F 1 349 LYS 349 438 ?   ?   ?   F . n 
F 1 350 GLN 350 439 ?   ?   ?   F . n 
F 1 351 GLY 351 440 ?   ?   ?   F . n 
F 1 352 LEU 352 441 ?   ?   ?   F . n 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9H5J 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9H5J 
_struct.title                        'PAD12 0N3R tau PHF seeded by AD' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9H5J 
_struct_keywords.text            'Amyloid, alzheimer, PROTEIN FIBRIL' 
_struct_keywords.pdbx_keywords   'PROTEIN FIBRIL' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 1 ? 
F N N 1 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    TAU_HUMAN 
_struct_ref.pdbx_db_accession          P10636 
_struct_ref.pdbx_db_isoform            P10636-2 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSD
DKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTP
PTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIH
HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLS
NVSSTGSIDMVDSPQLATLADEVSASLAKQGL
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9H5J A 1 ? 352 ? P10636 1 ? 352 ? 90 441 
2 1 9H5J B 1 ? 352 ? P10636 1 ? 352 ? 90 441 
3 1 9H5J C 1 ? 352 ? P10636 1 ? 352 ? 90 441 
4 1 9H5J D 1 ? 352 ? P10636 1 ? 352 ? 90 441 
5 1 9H5J E 1 ? 352 ? P10636 1 ? 352 ? 90 441 
6 1 9H5J F 1 ? 352 ? P10636 1 ? 352 ? 90 441 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9H5J ASP A 123 ? UNP P10636 THR 123 conflict 212 1  
1 9H5J ASP A 144 ? UNP P10636 SER 144 conflict 233 2  
1 9H5J ASP A 147 ? UNP P10636 THR 147 conflict 236 3  
1 9H5J ASP A 154 ? UNP P10636 THR 154 conflict 243 4  
1 9H5J ASP A 156 ? UNP P10636 SER 156 conflict 245 5  
1 9H5J ASP A 159 ? UNP P10636 THR 159 conflict 248 6  
1 9H5J ASP A 173 ? UNP P10636 THR 173 conflict 262 7  
1 9H5J ASP A 177 ? UNP P10636 SER 177 conflict 266 8  
1 9H5J ASP A 307 ? UNP P10636 SER 307 conflict 396 9  
1 9H5J ASP A 311 ? UNP P10636 SER 311 conflict 400 10 
1 9H5J ASP A 314 ? UNP P10636 THR 314 conflict 403 11 
1 9H5J ASP A 315 ? UNP P10636 SER 315 conflict 404 12 
2 9H5J ASP B 123 ? UNP P10636 THR 123 conflict 212 13 
2 9H5J ASP B 144 ? UNP P10636 SER 144 conflict 233 14 
2 9H5J ASP B 147 ? UNP P10636 THR 147 conflict 236 15 
2 9H5J ASP B 154 ? UNP P10636 THR 154 conflict 243 16 
2 9H5J ASP B 156 ? UNP P10636 SER 156 conflict 245 17 
2 9H5J ASP B 159 ? UNP P10636 THR 159 conflict 248 18 
2 9H5J ASP B 173 ? UNP P10636 THR 173 conflict 262 19 
2 9H5J ASP B 177 ? UNP P10636 SER 177 conflict 266 20 
2 9H5J ASP B 307 ? UNP P10636 SER 307 conflict 396 21 
2 9H5J ASP B 311 ? UNP P10636 SER 311 conflict 400 22 
2 9H5J ASP B 314 ? UNP P10636 THR 314 conflict 403 23 
2 9H5J ASP B 315 ? UNP P10636 SER 315 conflict 404 24 
3 9H5J ASP C 123 ? UNP P10636 THR 123 conflict 212 25 
3 9H5J ASP C 144 ? UNP P10636 SER 144 conflict 233 26 
3 9H5J ASP C 147 ? UNP P10636 THR 147 conflict 236 27 
3 9H5J ASP C 154 ? UNP P10636 THR 154 conflict 243 28 
3 9H5J ASP C 156 ? UNP P10636 SER 156 conflict 245 29 
3 9H5J ASP C 159 ? UNP P10636 THR 159 conflict 248 30 
3 9H5J ASP C 173 ? UNP P10636 THR 173 conflict 262 31 
3 9H5J ASP C 177 ? UNP P10636 SER 177 conflict 266 32 
3 9H5J ASP C 307 ? UNP P10636 SER 307 conflict 396 33 
3 9H5J ASP C 311 ? UNP P10636 SER 311 conflict 400 34 
3 9H5J ASP C 314 ? UNP P10636 THR 314 conflict 403 35 
3 9H5J ASP C 315 ? UNP P10636 SER 315 conflict 404 36 
4 9H5J ASP D 123 ? UNP P10636 THR 123 conflict 212 37 
4 9H5J ASP D 144 ? UNP P10636 SER 144 conflict 233 38 
4 9H5J ASP D 147 ? UNP P10636 THR 147 conflict 236 39 
4 9H5J ASP D 154 ? UNP P10636 THR 154 conflict 243 40 
4 9H5J ASP D 156 ? UNP P10636 SER 156 conflict 245 41 
4 9H5J ASP D 159 ? UNP P10636 THR 159 conflict 248 42 
4 9H5J ASP D 173 ? UNP P10636 THR 173 conflict 262 43 
4 9H5J ASP D 177 ? UNP P10636 SER 177 conflict 266 44 
4 9H5J ASP D 307 ? UNP P10636 SER 307 conflict 396 45 
4 9H5J ASP D 311 ? UNP P10636 SER 311 conflict 400 46 
4 9H5J ASP D 314 ? UNP P10636 THR 314 conflict 403 47 
4 9H5J ASP D 315 ? UNP P10636 SER 315 conflict 404 48 
5 9H5J ASP E 123 ? UNP P10636 THR 123 conflict 212 49 
5 9H5J ASP E 144 ? UNP P10636 SER 144 conflict 233 50 
5 9H5J ASP E 147 ? UNP P10636 THR 147 conflict 236 51 
5 9H5J ASP E 154 ? UNP P10636 THR 154 conflict 243 52 
5 9H5J ASP E 156 ? UNP P10636 SER 156 conflict 245 53 
5 9H5J ASP E 159 ? UNP P10636 THR 159 conflict 248 54 
5 9H5J ASP E 173 ? UNP P10636 THR 173 conflict 262 55 
5 9H5J ASP E 177 ? UNP P10636 SER 177 conflict 266 56 
5 9H5J ASP E 307 ? UNP P10636 SER 307 conflict 396 57 
5 9H5J ASP E 311 ? UNP P10636 SER 311 conflict 400 58 
5 9H5J ASP E 314 ? UNP P10636 THR 314 conflict 403 59 
5 9H5J ASP E 315 ? UNP P10636 SER 315 conflict 404 60 
6 9H5J ASP F 123 ? UNP P10636 THR 123 conflict 212 61 
6 9H5J ASP F 144 ? UNP P10636 SER 144 conflict 233 62 
6 9H5J ASP F 147 ? UNP P10636 THR 147 conflict 236 63 
6 9H5J ASP F 154 ? UNP P10636 THR 154 conflict 243 64 
6 9H5J ASP F 156 ? UNP P10636 SER 156 conflict 245 65 
6 9H5J ASP F 159 ? UNP P10636 THR 159 conflict 248 66 
6 9H5J ASP F 173 ? UNP P10636 THR 173 conflict 262 67 
6 9H5J ASP F 177 ? UNP P10636 SER 177 conflict 266 68 
6 9H5J ASP F 307 ? UNP P10636 SER 307 conflict 396 69 
6 9H5J ASP F 311 ? UNP P10636 SER 311 conflict 400 70 
6 9H5J ASP F 314 ? UNP P10636 THR 314 conflict 403 71 
6 9H5J ASP F 315 ? UNP P10636 SER 315 conflict 404 72 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 3 ? 
AA3 ? 3 ? 
AA4 ? 3 ? 
AA5 ? 3 ? 
AA6 ? 3 ? 
AA7 ? 3 ? 
AA8 ? 3 ? 
AA9 ? 3 ? 
AB1 ? 3 ? 
AB2 ? 3 ? 
AB3 ? 3 ? 
AB4 ? 3 ? 
AB5 ? 3 ? 
AB6 ? 3 ? 
AB7 ? 3 ? 
AB8 ? 3 ? 
AB9 ? 3 ? 
AC1 ? 3 ? 
AC2 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel 
AA1 2 3 ? parallel 
AA2 1 2 ? parallel 
AA2 2 3 ? parallel 
AA3 1 2 ? parallel 
AA3 2 3 ? parallel 
AA4 1 2 ? parallel 
AA4 2 3 ? parallel 
AA5 1 2 ? parallel 
AA5 2 3 ? parallel 
AA6 1 2 ? parallel 
AA6 2 3 ? parallel 
AA7 1 2 ? parallel 
AA7 2 3 ? parallel 
AA8 1 2 ? parallel 
AA8 2 3 ? parallel 
AA9 1 2 ? parallel 
AA9 2 3 ? parallel 
AB1 1 2 ? parallel 
AB1 2 3 ? parallel 
AB2 1 2 ? parallel 
AB2 2 3 ? parallel 
AB3 1 2 ? parallel 
AB3 2 3 ? parallel 
AB4 1 2 ? parallel 
AB4 2 3 ? parallel 
AB5 1 2 ? parallel 
AB5 2 3 ? parallel 
AB6 1 2 ? parallel 
AB6 2 3 ? parallel 
AB7 1 2 ? parallel 
AB7 2 3 ? parallel 
AB8 1 2 ? parallel 
AB8 2 3 ? parallel 
AB9 1 2 ? parallel 
AB9 2 3 ? parallel 
AC1 1 2 ? parallel 
AC1 2 3 ? parallel 
AC2 1 2 ? parallel 
AC2 2 3 ? parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 219 ? TYR A 221 ? ILE A 308 TYR A 310 
AA1 2 ILE D 219 ? TYR D 221 ? ILE D 308 TYR D 310 
AA1 3 ILE B 219 ? TYR B 221 ? ILE B 308 TYR B 310 
AA2 1 VAL A 224 ? ASP A 225 ? VAL A 313 ASP A 314 
AA2 2 VAL D 224 ? ASP D 225 ? VAL D 313 ASP D 314 
AA2 3 VAL B 224 ? ASP B 225 ? VAL B 313 ASP B 314 
AA3 1 LYS A 228 ? CYS A 233 ? LYS A 317 CYS A 322 
AA3 2 LYS D 228 ? CYS D 233 ? LYS D 317 CYS D 322 
AA3 3 LYS B 228 ? CYS B 233 ? LYS B 317 CYS B 322 
AA4 1 LEU A 236 ? HIS A 241 ? LEU A 325 HIS A 330 
AA4 2 LEU D 236 ? HIS D 241 ? LEU D 325 HIS D 330 
AA4 3 LEU B 236 ? HIS B 241 ? LEU B 325 HIS B 330 
AA5 1 GLN A 247 ? LYS A 251 ? GLN A 336 LYS A 340 
AA5 2 GLN D 247 ? LYS D 251 ? GLN D 336 LYS D 340 
AA5 3 GLN B 247 ? LYS B 251 ? GLN B 336 LYS B 340 
AA6 1 LYS A 254 ? LYS A 258 ? LYS A 343 LYS A 347 
AA6 2 LYS D 254 ? LYS D 258 ? LYS D 343 LYS D 347 
AA6 3 LYS B 254 ? LYS B 258 ? LYS B 343 LYS B 347 
AA7 1 VAL A 261 ? SER A 267 ? VAL A 350 SER A 356 
AA7 2 VAL D 261 ? SER D 267 ? VAL D 350 SER D 356 
AA7 3 VAL B 261 ? SER B 267 ? VAL B 350 SER B 356 
AA8 1 ASN A 270 ? HIS A 273 ? ASN A 359 HIS A 362 
AA8 2 ASN D 270 ? HIS D 273 ? ASN D 359 HIS D 362 
AA8 3 ASN B 270 ? HIS B 273 ? ASN B 359 HIS B 362 
AA9 1 LYS A 280 ? ILE A 282 ? LYS A 369 ILE A 371 
AA9 2 LYS D 280 ? ILE D 282 ? LYS D 369 ILE D 371 
AA9 3 LYS B 280 ? ILE B 282 ? LYS B 369 ILE B 371 
AB1 1 HIS A 285 ? THR A 288 ? HIS A 374 THR A 377 
AB1 2 HIS D 285 ? THR D 288 ? HIS D 374 THR D 377 
AB1 3 HIS B 285 ? THR B 288 ? HIS B 374 THR B 377 
AB2 1 ILE C 219 ? TYR C 221 ? ILE C 308 TYR C 310 
AB2 2 ILE E 219 ? TYR E 221 ? ILE E 308 TYR E 310 
AB2 3 ILE F 219 ? TYR F 221 ? ILE F 308 TYR F 310 
AB3 1 VAL C 224 ? ASP C 225 ? VAL C 313 ASP C 314 
AB3 2 VAL E 224 ? ASP E 225 ? VAL E 313 ASP E 314 
AB3 3 VAL F 224 ? ASP F 225 ? VAL F 313 ASP F 314 
AB4 1 LYS C 228 ? CYS C 233 ? LYS C 317 CYS C 322 
AB4 2 LYS E 228 ? CYS E 233 ? LYS E 317 CYS E 322 
AB4 3 LYS F 228 ? CYS F 233 ? LYS F 317 CYS F 322 
AB5 1 LEU C 236 ? HIS C 241 ? LEU C 325 HIS C 330 
AB5 2 LEU E 236 ? HIS E 241 ? LEU E 325 HIS E 330 
AB5 3 LEU F 236 ? HIS F 241 ? LEU F 325 HIS F 330 
AB6 1 GLN C 247 ? LYS C 251 ? GLN C 336 LYS C 340 
AB6 2 GLN E 247 ? LYS E 251 ? GLN E 336 LYS E 340 
AB6 3 GLN F 247 ? LYS F 251 ? GLN F 336 LYS F 340 
AB7 1 LYS C 254 ? LYS C 258 ? LYS C 343 LYS C 347 
AB7 2 LYS E 254 ? LYS E 258 ? LYS E 343 LYS E 347 
AB7 3 LYS F 254 ? LYS F 258 ? LYS F 343 LYS F 347 
AB8 1 VAL C 261 ? SER C 267 ? VAL C 350 SER C 356 
AB8 2 VAL E 261 ? SER E 267 ? VAL E 350 SER E 356 
AB8 3 VAL F 261 ? SER F 267 ? VAL F 350 SER F 356 
AB9 1 ASN C 270 ? HIS C 273 ? ASN C 359 HIS C 362 
AB9 2 ASN E 270 ? HIS E 273 ? ASN E 359 HIS E 362 
AB9 3 ASN F 270 ? HIS F 273 ? ASN F 359 HIS F 362 
AC1 1 LYS C 280 ? ILE C 282 ? LYS C 369 ILE C 371 
AC1 2 LYS E 280 ? ILE E 282 ? LYS E 369 ILE E 371 
AC1 3 LYS F 280 ? ILE F 282 ? LYS F 369 ILE F 371 
AC2 1 HIS C 285 ? THR C 288 ? HIS C 374 THR C 377 
AC2 2 HIS E 285 ? THR E 288 ? HIS E 374 THR E 377 
AC2 3 HIS F 285 ? THR F 288 ? HIS F 374 THR F 377 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 220 ? N VAL A 309 O ILE D 219 ? O ILE D 308 
AA1 2 3 O VAL D 220 ? O VAL D 309 N ILE B 219 ? N ILE B 308 
AA2 1 2 N VAL A 224 ? N VAL A 313 O ASP D 225 ? O ASP D 314 
AA2 2 3 O VAL D 224 ? O VAL D 313 N ASP B 225 ? N ASP B 314 
AA3 1 2 N THR A 230 ? N THR A 319 O VAL D 229 ? O VAL D 318 
AA3 2 3 O THR D 230 ? O THR D 319 N VAL B 229 ? N VAL B 318 
AA4 1 2 N HIS A 240 ? N HIS A 329 O ILE D 239 ? O ILE D 328 
AA4 2 3 O HIS D 240 ? O HIS D 329 N HIS B 241 ? N HIS B 330 
AA5 1 2 N GLN A 247 ? N GLN A 336 O VAL D 248 ? O VAL D 337 
AA5 2 3 O GLN D 247 ? O GLN D 336 N VAL B 248 ? N VAL B 337 
AA6 1 2 N LYS A 258 ? N LYS A 347 O PHE D 257 ? O PHE D 346 
AA6 2 3 O LYS D 258 ? O LYS D 347 N PHE B 257 ? N PHE B 346 
AA7 1 2 N GLN A 262 ? N GLN A 351 O VAL D 261 ? O VAL D 350 
AA7 2 3 O GLN D 262 ? O GLN D 351 N VAL B 261 ? N VAL B 350 
AA8 1 2 N HIS A 273 ? N HIS A 362 O THR D 272 ? O THR D 361 
AA8 2 3 O HIS D 273 ? O HIS D 362 N THR B 272 ? N THR B 361 
AA9 1 2 N ILE A 282 ? N ILE A 371 O LYS D 281 ? O LYS D 370 
AA9 2 3 O ILE D 282 ? O ILE D 371 N LYS B 281 ? N LYS B 370 
AB1 1 2 N LYS A 286 ? N LYS A 375 O HIS D 285 ? O HIS D 374 
AB1 2 3 O LYS D 286 ? O LYS D 375 N HIS B 285 ? N HIS B 374 
AB2 1 2 N ILE C 219 ? N ILE C 308 O VAL E 220 ? O VAL E 309 
AB2 2 3 N ILE E 219 ? N ILE E 308 O VAL F 220 ? O VAL F 309 
AB3 1 2 N ASP C 225 ? N ASP C 314 O VAL E 224 ? O VAL E 313 
AB3 2 3 N ASP E 225 ? N ASP E 314 O VAL F 224 ? O VAL F 313 
AB4 1 2 N VAL C 229 ? N VAL C 318 O LYS E 228 ? O LYS E 317 
AB4 2 3 N VAL E 229 ? N VAL E 318 O LYS F 228 ? O LYS F 317 
AB5 1 2 N HIS C 241 ? N HIS C 330 O HIS E 240 ? O HIS E 329 
AB5 2 3 N HIS E 241 ? N HIS E 330 O HIS F 240 ? O HIS F 329 
AB6 1 2 N VAL C 248 ? N VAL C 337 O GLN E 247 ? O GLN E 336 
AB6 2 3 N VAL E 248 ? N VAL E 337 O GLN F 247 ? O GLN F 336 
AB7 1 2 N PHE C 257 ? N PHE C 346 O LYS E 258 ? O LYS E 347 
AB7 2 3 N PHE E 257 ? N PHE E 346 O LYS F 258 ? O LYS F 347 
AB8 1 2 N VAL C 261 ? N VAL C 350 O GLN E 262 ? O GLN E 351 
AB8 2 3 N VAL E 261 ? N VAL E 350 O GLN F 262 ? O GLN F 351 
AB9 1 2 N THR C 272 ? N THR C 361 O HIS E 273 ? O HIS E 362 
AB9 2 3 N THR E 272 ? N THR E 361 O HIS F 273 ? O HIS F 362 
AC1 1 2 N LYS C 281 ? N LYS C 370 O ILE E 282 ? O ILE E 371 
AC1 2 3 N LYS E 281 ? N LYS E 370 O ILE F 282 ? O ILE F 371 
AC2 1 2 N HIS C 285 ? N HIS C 374 O LYS E 286 ? O LYS E 375 
AC2 2 3 N HIS E 285 ? N HIS E 374 O LYS F 286 ? O LYS F 375 
# 
_pdbx_entry_details.entry_id                   9H5J 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 348 ? ? 59.33   91.07 
2  1 LYS B 311 ? ? -140.34 55.09 
3  1 ASP B 348 ? ? 58.17   89.44 
4  1 LYS C 311 ? ? -140.32 54.11 
5  1 ASP C 348 ? ? 57.40   89.42 
6  1 ASP D 348 ? ? 59.18   89.06 
7  1 LYS E 311 ? ? -140.31 54.92 
8  1 ASP E 348 ? ? 59.66   88.63 
9  1 LYS F 311 ? ? -142.71 57.30 
10 1 ASP F 348 ? ? 58.27   89.02 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG D 349 ? ? 0.076 'SIDE CHAIN' 
2 1 ARG E 349 ? ? 0.082 'SIDE CHAIN' 
3 1 TYR F 310 ? ? 0.068 'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9H5J 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9H5J 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   'FOURIER SPACE' 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.72 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               125334 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               HELICAL 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.28 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Amyloid filament of tau' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9H5J 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             500 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9H5J 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9H5J 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   HELICAL 
_em_experiment.aggregation_state       FILAMENT 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1    1 Y 1 A MET 90  ? A MET 1   
2    1 Y 1 A ALA 91  ? A ALA 2   
3    1 Y 1 A GLU 92  ? A GLU 3   
4    1 Y 1 A PRO 93  ? A PRO 4   
5    1 Y 1 A ARG 94  ? A ARG 5   
6    1 Y 1 A GLN 95  ? A GLN 6   
7    1 Y 1 A GLU 96  ? A GLU 7   
8    1 Y 1 A PHE 97  ? A PHE 8   
9    1 Y 1 A GLU 98  ? A GLU 9   
10   1 Y 1 A VAL 99  ? A VAL 10  
11   1 Y 1 A MET 100 ? A MET 11  
12   1 Y 1 A GLU 101 ? A GLU 12  
13   1 Y 1 A ASP 102 ? A ASP 13  
14   1 Y 1 A HIS 103 ? A HIS 14  
15   1 Y 1 A ALA 104 ? A ALA 15  
16   1 Y 1 A GLY 105 ? A GLY 16  
17   1 Y 1 A THR 106 ? A THR 17  
18   1 Y 1 A TYR 107 ? A TYR 18  
19   1 Y 1 A GLY 108 ? A GLY 19  
20   1 Y 1 A LEU 109 ? A LEU 20  
21   1 Y 1 A GLY 110 ? A GLY 21  
22   1 Y 1 A ASP 111 ? A ASP 22  
23   1 Y 1 A ARG 112 ? A ARG 23  
24   1 Y 1 A LYS 113 ? A LYS 24  
25   1 Y 1 A ASP 114 ? A ASP 25  
26   1 Y 1 A GLN 115 ? A GLN 26  
27   1 Y 1 A GLY 116 ? A GLY 27  
28   1 Y 1 A GLY 117 ? A GLY 28  
29   1 Y 1 A TYR 118 ? A TYR 29  
30   1 Y 1 A THR 119 ? A THR 30  
31   1 Y 1 A MET 120 ? A MET 31  
32   1 Y 1 A HIS 121 ? A HIS 32  
33   1 Y 1 A GLN 122 ? A GLN 33  
34   1 Y 1 A ASP 123 ? A ASP 34  
35   1 Y 1 A GLN 124 ? A GLN 35  
36   1 Y 1 A GLU 125 ? A GLU 36  
37   1 Y 1 A GLY 126 ? A GLY 37  
38   1 Y 1 A ASP 127 ? A ASP 38  
39   1 Y 1 A THR 128 ? A THR 39  
40   1 Y 1 A ASP 129 ? A ASP 40  
41   1 Y 1 A ALA 130 ? A ALA 41  
42   1 Y 1 A GLY 131 ? A GLY 42  
43   1 Y 1 A LEU 132 ? A LEU 43  
44   1 Y 1 A LYS 133 ? A LYS 44  
45   1 Y 1 A ALA 134 ? A ALA 45  
46   1 Y 1 A GLU 135 ? A GLU 46  
47   1 Y 1 A GLU 136 ? A GLU 47  
48   1 Y 1 A ALA 137 ? A ALA 48  
49   1 Y 1 A GLY 138 ? A GLY 49  
50   1 Y 1 A ILE 139 ? A ILE 50  
51   1 Y 1 A GLY 140 ? A GLY 51  
52   1 Y 1 A ASP 141 ? A ASP 52  
53   1 Y 1 A THR 142 ? A THR 53  
54   1 Y 1 A PRO 143 ? A PRO 54  
55   1 Y 1 A SER 144 ? A SER 55  
56   1 Y 1 A LEU 145 ? A LEU 56  
57   1 Y 1 A GLU 146 ? A GLU 57  
58   1 Y 1 A ASP 147 ? A ASP 58  
59   1 Y 1 A GLU 148 ? A GLU 59  
60   1 Y 1 A ALA 149 ? A ALA 60  
61   1 Y 1 A ALA 150 ? A ALA 61  
62   1 Y 1 A GLY 151 ? A GLY 62  
63   1 Y 1 A HIS 152 ? A HIS 63  
64   1 Y 1 A VAL 153 ? A VAL 64  
65   1 Y 1 A THR 154 ? A THR 65  
66   1 Y 1 A GLN 155 ? A GLN 66  
67   1 Y 1 A ALA 156 ? A ALA 67  
68   1 Y 1 A ARG 157 ? A ARG 68  
69   1 Y 1 A MET 158 ? A MET 69  
70   1 Y 1 A VAL 159 ? A VAL 70  
71   1 Y 1 A SER 160 ? A SER 71  
72   1 Y 1 A LYS 161 ? A LYS 72  
73   1 Y 1 A SER 162 ? A SER 73  
74   1 Y 1 A LYS 163 ? A LYS 74  
75   1 Y 1 A ASP 164 ? A ASP 75  
76   1 Y 1 A GLY 165 ? A GLY 76  
77   1 Y 1 A THR 166 ? A THR 77  
78   1 Y 1 A GLY 167 ? A GLY 78  
79   1 Y 1 A SER 168 ? A SER 79  
80   1 Y 1 A ASP 169 ? A ASP 80  
81   1 Y 1 A ASP 170 ? A ASP 81  
82   1 Y 1 A LYS 171 ? A LYS 82  
83   1 Y 1 A LYS 172 ? A LYS 83  
84   1 Y 1 A ALA 173 ? A ALA 84  
85   1 Y 1 A LYS 174 ? A LYS 85  
86   1 Y 1 A GLY 175 ? A GLY 86  
87   1 Y 1 A ALA 176 ? A ALA 87  
88   1 Y 1 A ASP 177 ? A ASP 88  
89   1 Y 1 A GLY 178 ? A GLY 89  
90   1 Y 1 A LYS 179 ? A LYS 90  
91   1 Y 1 A THR 180 ? A THR 91  
92   1 Y 1 A LYS 181 ? A LYS 92  
93   1 Y 1 A ILE 182 ? A ILE 93  
94   1 Y 1 A ALA 183 ? A ALA 94  
95   1 Y 1 A THR 184 ? A THR 95  
96   1 Y 1 A PRO 185 ? A PRO 96  
97   1 Y 1 A ARG 186 ? A ARG 97  
98   1 Y 1 A GLY 187 ? A GLY 98  
99   1 Y 1 A ALA 188 ? A ALA 99  
100  1 Y 1 A ALA 189 ? A ALA 100 
101  1 Y 1 A PRO 190 ? A PRO 101 
102  1 Y 1 A PRO 191 ? A PRO 102 
103  1 Y 1 A GLY 192 ? A GLY 103 
104  1 Y 1 A GLN 193 ? A GLN 104 
105  1 Y 1 A LYS 194 ? A LYS 105 
106  1 Y 1 A GLY 195 ? A GLY 106 
107  1 Y 1 A GLN 196 ? A GLN 107 
108  1 Y 1 A ALA 197 ? A ALA 108 
109  1 Y 1 A ASN 198 ? A ASN 109 
110  1 Y 1 A ALA 199 ? A ALA 110 
111  1 Y 1 A THR 200 ? A THR 111 
112  1 Y 1 A ARG 201 ? A ARG 112 
113  1 Y 1 A ILE 202 ? A ILE 113 
114  1 Y 1 A PRO 203 ? A PRO 114 
115  1 Y 1 A ALA 204 ? A ALA 115 
116  1 Y 1 A LYS 205 ? A LYS 116 
117  1 Y 1 A THR 206 ? A THR 117 
118  1 Y 1 A PRO 207 ? A PRO 118 
119  1 Y 1 A PRO 208 ? A PRO 119 
120  1 Y 1 A ALA 209 ? A ALA 120 
121  1 Y 1 A PRO 210 ? A PRO 121 
122  1 Y 1 A LYS 211 ? A LYS 122 
123  1 Y 1 A ASP 212 ? A ASP 123 
124  1 Y 1 A PRO 213 ? A PRO 124 
125  1 Y 1 A PRO 214 ? A PRO 125 
126  1 Y 1 A SER 215 ? A SER 126 
127  1 Y 1 A SER 216 ? A SER 127 
128  1 Y 1 A GLY 217 ? A GLY 128 
129  1 Y 1 A GLU 218 ? A GLU 129 
130  1 Y 1 A PRO 219 ? A PRO 130 
131  1 Y 1 A PRO 220 ? A PRO 131 
132  1 Y 1 A LYS 221 ? A LYS 132 
133  1 Y 1 A SER 222 ? A SER 133 
134  1 Y 1 A GLY 223 ? A GLY 134 
135  1 Y 1 A ASP 224 ? A ASP 135 
136  1 Y 1 A ARG 225 ? A ARG 136 
137  1 Y 1 A SER 226 ? A SER 137 
138  1 Y 1 A GLY 227 ? A GLY 138 
139  1 Y 1 A TYR 228 ? A TYR 139 
140  1 Y 1 A SER 229 ? A SER 140 
141  1 Y 1 A SER 230 ? A SER 141 
142  1 Y 1 A PRO 231 ? A PRO 142 
143  1 Y 1 A GLY 232 ? A GLY 143 
144  1 Y 1 A ASP 233 ? A ASP 144 
145  1 Y 1 A PRO 234 ? A PRO 145 
146  1 Y 1 A GLY 235 ? A GLY 146 
147  1 Y 1 A ASP 236 ? A ASP 147 
148  1 Y 1 A PRO 237 ? A PRO 148 
149  1 Y 1 A GLY 238 ? A GLY 149 
150  1 Y 1 A SER 239 ? A SER 150 
151  1 Y 1 A ARG 240 ? A ARG 151 
152  1 Y 1 A SER 241 ? A SER 152 
153  1 Y 1 A ARG 242 ? A ARG 153 
154  1 Y 1 A ASP 243 ? A ASP 154 
155  1 Y 1 A PRO 244 ? A PRO 155 
156  1 Y 1 A ASP 245 ? A ASP 156 
157  1 Y 1 A LEU 246 ? A LEU 157 
158  1 Y 1 A PRO 247 ? A PRO 158 
159  1 Y 1 A ASP 248 ? A ASP 159 
160  1 Y 1 A PRO 249 ? A PRO 160 
161  1 Y 1 A PRO 250 ? A PRO 161 
162  1 Y 1 A THR 251 ? A THR 162 
163  1 Y 1 A ARG 252 ? A ARG 163 
164  1 Y 1 A GLU 253 ? A GLU 164 
165  1 Y 1 A PRO 254 ? A PRO 165 
166  1 Y 1 A LYS 255 ? A LYS 166 
167  1 Y 1 A LYS 256 ? A LYS 167 
168  1 Y 1 A VAL 257 ? A VAL 168 
169  1 Y 1 A ALA 258 ? A ALA 169 
170  1 Y 1 A VAL 259 ? A VAL 170 
171  1 Y 1 A VAL 260 ? A VAL 171 
172  1 Y 1 A ARG 261 ? A ARG 172 
173  1 Y 1 A ASP 262 ? A ASP 173 
174  1 Y 1 A PRO 263 ? A PRO 174 
175  1 Y 1 A PRO 264 ? A PRO 175 
176  1 Y 1 A LYS 265 ? A LYS 176 
177  1 Y 1 A ASP 266 ? A ASP 177 
178  1 Y 1 A PRO 267 ? A PRO 178 
179  1 Y 1 A SER 268 ? A SER 179 
180  1 Y 1 A SER 269 ? A SER 180 
181  1 Y 1 A ALA 270 ? A ALA 181 
182  1 Y 1 A LYS 271 ? A LYS 182 
183  1 Y 1 A SER 272 ? A SER 183 
184  1 Y 1 A ARG 273 ? A ARG 184 
185  1 Y 1 A LEU 274 ? A LEU 185 
186  1 Y 1 A GLN 275 ? A GLN 186 
187  1 Y 1 A THR 276 ? A THR 187 
188  1 Y 1 A ALA 277 ? A ALA 188 
189  1 Y 1 A PRO 278 ? A PRO 189 
190  1 Y 1 A VAL 279 ? A VAL 190 
191  1 Y 1 A PRO 280 ? A PRO 191 
192  1 Y 1 A MET 281 ? A MET 192 
193  1 Y 1 A PRO 282 ? A PRO 193 
194  1 Y 1 A ASP 283 ? A ASP 194 
195  1 Y 1 A LEU 284 ? A LEU 195 
196  1 Y 1 A LYS 285 ? A LYS 196 
197  1 Y 1 A ASN 286 ? A ASN 197 
198  1 Y 1 A VAL 287 ? A VAL 198 
199  1 Y 1 A LYS 288 ? A LYS 199 
200  1 Y 1 A SER 289 ? A SER 200 
201  1 Y 1 A LYS 290 ? A LYS 201 
202  1 Y 1 A ILE 291 ? A ILE 202 
203  1 Y 1 A GLY 292 ? A GLY 203 
204  1 Y 1 A SER 293 ? A SER 204 
205  1 Y 1 A THR 294 ? A THR 205 
206  1 Y 1 A GLU 295 ? A GLU 206 
207  1 Y 1 A ASN 296 ? A ASN 207 
208  1 Y 1 A LEU 297 ? A LEU 208 
209  1 Y 1 A LYS 298 ? A LYS 209 
210  1 Y 1 A HIS 299 ? A HIS 210 
211  1 Y 1 A GLN 300 ? A GLN 211 
212  1 Y 1 A PRO 301 ? A PRO 212 
213  1 Y 1 A GLY 302 ? A GLY 213 
214  1 Y 1 A GLY 303 ? A GLY 214 
215  1 Y 1 A GLY 304 ? A GLY 215 
216  1 Y 1 A LYS 305 ? A LYS 216 
217  1 Y 1 A VAL 306 ? A VAL 217 
218  1 Y 1 A ARG 379 ? A ARG 290 
219  1 Y 1 A GLU 380 ? A GLU 291 
220  1 Y 1 A ASN 381 ? A ASN 292 
221  1 Y 1 A ALA 382 ? A ALA 293 
222  1 Y 1 A LYS 383 ? A LYS 294 
223  1 Y 1 A ALA 384 ? A ALA 295 
224  1 Y 1 A LYS 385 ? A LYS 296 
225  1 Y 1 A THR 386 ? A THR 297 
226  1 Y 1 A ASP 387 ? A ASP 298 
227  1 Y 1 A HIS 388 ? A HIS 299 
228  1 Y 1 A GLY 389 ? A GLY 300 
229  1 Y 1 A ALA 390 ? A ALA 301 
230  1 Y 1 A GLU 391 ? A GLU 302 
231  1 Y 1 A ILE 392 ? A ILE 303 
232  1 Y 1 A VAL 393 ? A VAL 304 
233  1 Y 1 A TYR 394 ? A TYR 305 
234  1 Y 1 A LYS 395 ? A LYS 306 
235  1 Y 1 A ASP 396 ? A ASP 307 
236  1 Y 1 A PRO 397 ? A PRO 308 
237  1 Y 1 A VAL 398 ? A VAL 309 
238  1 Y 1 A VAL 399 ? A VAL 310 
239  1 Y 1 A ASP 400 ? A ASP 311 
240  1 Y 1 A GLY 401 ? A GLY 312 
241  1 Y 1 A ASP 402 ? A ASP 313 
242  1 Y 1 A ASP 403 ? A ASP 314 
243  1 Y 1 A ASP 404 ? A ASP 315 
244  1 Y 1 A PRO 405 ? A PRO 316 
245  1 Y 1 A ARG 406 ? A ARG 317 
246  1 Y 1 A HIS 407 ? A HIS 318 
247  1 Y 1 A LEU 408 ? A LEU 319 
248  1 Y 1 A SER 409 ? A SER 320 
249  1 Y 1 A ASN 410 ? A ASN 321 
250  1 Y 1 A VAL 411 ? A VAL 322 
251  1 Y 1 A SER 412 ? A SER 323 
252  1 Y 1 A SER 413 ? A SER 324 
253  1 Y 1 A THR 414 ? A THR 325 
254  1 Y 1 A GLY 415 ? A GLY 326 
255  1 Y 1 A SER 416 ? A SER 327 
256  1 Y 1 A ILE 417 ? A ILE 328 
257  1 Y 1 A ASP 418 ? A ASP 329 
258  1 Y 1 A MET 419 ? A MET 330 
259  1 Y 1 A VAL 420 ? A VAL 331 
260  1 Y 1 A ASP 421 ? A ASP 332 
261  1 Y 1 A SER 422 ? A SER 333 
262  1 Y 1 A PRO 423 ? A PRO 334 
263  1 Y 1 A GLN 424 ? A GLN 335 
264  1 Y 1 A LEU 425 ? A LEU 336 
265  1 Y 1 A ALA 426 ? A ALA 337 
266  1 Y 1 A THR 427 ? A THR 338 
267  1 Y 1 A LEU 428 ? A LEU 339 
268  1 Y 1 A ALA 429 ? A ALA 340 
269  1 Y 1 A ASP 430 ? A ASP 341 
270  1 Y 1 A GLU 431 ? A GLU 342 
271  1 Y 1 A VAL 432 ? A VAL 343 
272  1 Y 1 A SER 433 ? A SER 344 
273  1 Y 1 A ALA 434 ? A ALA 345 
274  1 Y 1 A SER 435 ? A SER 346 
275  1 Y 1 A LEU 436 ? A LEU 347 
276  1 Y 1 A ALA 437 ? A ALA 348 
277  1 Y 1 A LYS 438 ? A LYS 349 
278  1 Y 1 A GLN 439 ? A GLN 350 
279  1 Y 1 A GLY 440 ? A GLY 351 
280  1 Y 1 A LEU 441 ? A LEU 352 
281  1 Y 1 B MET 90  ? B MET 1   
282  1 Y 1 B ALA 91  ? B ALA 2   
283  1 Y 1 B GLU 92  ? B GLU 3   
284  1 Y 1 B PRO 93  ? B PRO 4   
285  1 Y 1 B ARG 94  ? B ARG 5   
286  1 Y 1 B GLN 95  ? B GLN 6   
287  1 Y 1 B GLU 96  ? B GLU 7   
288  1 Y 1 B PHE 97  ? B PHE 8   
289  1 Y 1 B GLU 98  ? B GLU 9   
290  1 Y 1 B VAL 99  ? B VAL 10  
291  1 Y 1 B MET 100 ? B MET 11  
292  1 Y 1 B GLU 101 ? B GLU 12  
293  1 Y 1 B ASP 102 ? B ASP 13  
294  1 Y 1 B HIS 103 ? B HIS 14  
295  1 Y 1 B ALA 104 ? B ALA 15  
296  1 Y 1 B GLY 105 ? B GLY 16  
297  1 Y 1 B THR 106 ? B THR 17  
298  1 Y 1 B TYR 107 ? B TYR 18  
299  1 Y 1 B GLY 108 ? B GLY 19  
300  1 Y 1 B LEU 109 ? B LEU 20  
301  1 Y 1 B GLY 110 ? B GLY 21  
302  1 Y 1 B ASP 111 ? B ASP 22  
303  1 Y 1 B ARG 112 ? B ARG 23  
304  1 Y 1 B LYS 113 ? B LYS 24  
305  1 Y 1 B ASP 114 ? B ASP 25  
306  1 Y 1 B GLN 115 ? B GLN 26  
307  1 Y 1 B GLY 116 ? B GLY 27  
308  1 Y 1 B GLY 117 ? B GLY 28  
309  1 Y 1 B TYR 118 ? B TYR 29  
310  1 Y 1 B THR 119 ? B THR 30  
311  1 Y 1 B MET 120 ? B MET 31  
312  1 Y 1 B HIS 121 ? B HIS 32  
313  1 Y 1 B GLN 122 ? B GLN 33  
314  1 Y 1 B ASP 123 ? B ASP 34  
315  1 Y 1 B GLN 124 ? B GLN 35  
316  1 Y 1 B GLU 125 ? B GLU 36  
317  1 Y 1 B GLY 126 ? B GLY 37  
318  1 Y 1 B ASP 127 ? B ASP 38  
319  1 Y 1 B THR 128 ? B THR 39  
320  1 Y 1 B ASP 129 ? B ASP 40  
321  1 Y 1 B ALA 130 ? B ALA 41  
322  1 Y 1 B GLY 131 ? B GLY 42  
323  1 Y 1 B LEU 132 ? B LEU 43  
324  1 Y 1 B LYS 133 ? B LYS 44  
325  1 Y 1 B ALA 134 ? B ALA 45  
326  1 Y 1 B GLU 135 ? B GLU 46  
327  1 Y 1 B GLU 136 ? B GLU 47  
328  1 Y 1 B ALA 137 ? B ALA 48  
329  1 Y 1 B GLY 138 ? B GLY 49  
330  1 Y 1 B ILE 139 ? B ILE 50  
331  1 Y 1 B GLY 140 ? B GLY 51  
332  1 Y 1 B ASP 141 ? B ASP 52  
333  1 Y 1 B THR 142 ? B THR 53  
334  1 Y 1 B PRO 143 ? B PRO 54  
335  1 Y 1 B SER 144 ? B SER 55  
336  1 Y 1 B LEU 145 ? B LEU 56  
337  1 Y 1 B GLU 146 ? B GLU 57  
338  1 Y 1 B ASP 147 ? B ASP 58  
339  1 Y 1 B GLU 148 ? B GLU 59  
340  1 Y 1 B ALA 149 ? B ALA 60  
341  1 Y 1 B ALA 150 ? B ALA 61  
342  1 Y 1 B GLY 151 ? B GLY 62  
343  1 Y 1 B HIS 152 ? B HIS 63  
344  1 Y 1 B VAL 153 ? B VAL 64  
345  1 Y 1 B THR 154 ? B THR 65  
346  1 Y 1 B GLN 155 ? B GLN 66  
347  1 Y 1 B ALA 156 ? B ALA 67  
348  1 Y 1 B ARG 157 ? B ARG 68  
349  1 Y 1 B MET 158 ? B MET 69  
350  1 Y 1 B VAL 159 ? B VAL 70  
351  1 Y 1 B SER 160 ? B SER 71  
352  1 Y 1 B LYS 161 ? B LYS 72  
353  1 Y 1 B SER 162 ? B SER 73  
354  1 Y 1 B LYS 163 ? B LYS 74  
355  1 Y 1 B ASP 164 ? B ASP 75  
356  1 Y 1 B GLY 165 ? B GLY 76  
357  1 Y 1 B THR 166 ? B THR 77  
358  1 Y 1 B GLY 167 ? B GLY 78  
359  1 Y 1 B SER 168 ? B SER 79  
360  1 Y 1 B ASP 169 ? B ASP 80  
361  1 Y 1 B ASP 170 ? B ASP 81  
362  1 Y 1 B LYS 171 ? B LYS 82  
363  1 Y 1 B LYS 172 ? B LYS 83  
364  1 Y 1 B ALA 173 ? B ALA 84  
365  1 Y 1 B LYS 174 ? B LYS 85  
366  1 Y 1 B GLY 175 ? B GLY 86  
367  1 Y 1 B ALA 176 ? B ALA 87  
368  1 Y 1 B ASP 177 ? B ASP 88  
369  1 Y 1 B GLY 178 ? B GLY 89  
370  1 Y 1 B LYS 179 ? B LYS 90  
371  1 Y 1 B THR 180 ? B THR 91  
372  1 Y 1 B LYS 181 ? B LYS 92  
373  1 Y 1 B ILE 182 ? B ILE 93  
374  1 Y 1 B ALA 183 ? B ALA 94  
375  1 Y 1 B THR 184 ? B THR 95  
376  1 Y 1 B PRO 185 ? B PRO 96  
377  1 Y 1 B ARG 186 ? B ARG 97  
378  1 Y 1 B GLY 187 ? B GLY 98  
379  1 Y 1 B ALA 188 ? B ALA 99  
380  1 Y 1 B ALA 189 ? B ALA 100 
381  1 Y 1 B PRO 190 ? B PRO 101 
382  1 Y 1 B PRO 191 ? B PRO 102 
383  1 Y 1 B GLY 192 ? B GLY 103 
384  1 Y 1 B GLN 193 ? B GLN 104 
385  1 Y 1 B LYS 194 ? B LYS 105 
386  1 Y 1 B GLY 195 ? B GLY 106 
387  1 Y 1 B GLN 196 ? B GLN 107 
388  1 Y 1 B ALA 197 ? B ALA 108 
389  1 Y 1 B ASN 198 ? B ASN 109 
390  1 Y 1 B ALA 199 ? B ALA 110 
391  1 Y 1 B THR 200 ? B THR 111 
392  1 Y 1 B ARG 201 ? B ARG 112 
393  1 Y 1 B ILE 202 ? B ILE 113 
394  1 Y 1 B PRO 203 ? B PRO 114 
395  1 Y 1 B ALA 204 ? B ALA 115 
396  1 Y 1 B LYS 205 ? B LYS 116 
397  1 Y 1 B THR 206 ? B THR 117 
398  1 Y 1 B PRO 207 ? B PRO 118 
399  1 Y 1 B PRO 208 ? B PRO 119 
400  1 Y 1 B ALA 209 ? B ALA 120 
401  1 Y 1 B PRO 210 ? B PRO 121 
402  1 Y 1 B LYS 211 ? B LYS 122 
403  1 Y 1 B ASP 212 ? B ASP 123 
404  1 Y 1 B PRO 213 ? B PRO 124 
405  1 Y 1 B PRO 214 ? B PRO 125 
406  1 Y 1 B SER 215 ? B SER 126 
407  1 Y 1 B SER 216 ? B SER 127 
408  1 Y 1 B GLY 217 ? B GLY 128 
409  1 Y 1 B GLU 218 ? B GLU 129 
410  1 Y 1 B PRO 219 ? B PRO 130 
411  1 Y 1 B PRO 220 ? B PRO 131 
412  1 Y 1 B LYS 221 ? B LYS 132 
413  1 Y 1 B SER 222 ? B SER 133 
414  1 Y 1 B GLY 223 ? B GLY 134 
415  1 Y 1 B ASP 224 ? B ASP 135 
416  1 Y 1 B ARG 225 ? B ARG 136 
417  1 Y 1 B SER 226 ? B SER 137 
418  1 Y 1 B GLY 227 ? B GLY 138 
419  1 Y 1 B TYR 228 ? B TYR 139 
420  1 Y 1 B SER 229 ? B SER 140 
421  1 Y 1 B SER 230 ? B SER 141 
422  1 Y 1 B PRO 231 ? B PRO 142 
423  1 Y 1 B GLY 232 ? B GLY 143 
424  1 Y 1 B ASP 233 ? B ASP 144 
425  1 Y 1 B PRO 234 ? B PRO 145 
426  1 Y 1 B GLY 235 ? B GLY 146 
427  1 Y 1 B ASP 236 ? B ASP 147 
428  1 Y 1 B PRO 237 ? B PRO 148 
429  1 Y 1 B GLY 238 ? B GLY 149 
430  1 Y 1 B SER 239 ? B SER 150 
431  1 Y 1 B ARG 240 ? B ARG 151 
432  1 Y 1 B SER 241 ? B SER 152 
433  1 Y 1 B ARG 242 ? B ARG 153 
434  1 Y 1 B ASP 243 ? B ASP 154 
435  1 Y 1 B PRO 244 ? B PRO 155 
436  1 Y 1 B ASP 245 ? B ASP 156 
437  1 Y 1 B LEU 246 ? B LEU 157 
438  1 Y 1 B PRO 247 ? B PRO 158 
439  1 Y 1 B ASP 248 ? B ASP 159 
440  1 Y 1 B PRO 249 ? B PRO 160 
441  1 Y 1 B PRO 250 ? B PRO 161 
442  1 Y 1 B THR 251 ? B THR 162 
443  1 Y 1 B ARG 252 ? B ARG 163 
444  1 Y 1 B GLU 253 ? B GLU 164 
445  1 Y 1 B PRO 254 ? B PRO 165 
446  1 Y 1 B LYS 255 ? B LYS 166 
447  1 Y 1 B LYS 256 ? B LYS 167 
448  1 Y 1 B VAL 257 ? B VAL 168 
449  1 Y 1 B ALA 258 ? B ALA 169 
450  1 Y 1 B VAL 259 ? B VAL 170 
451  1 Y 1 B VAL 260 ? B VAL 171 
452  1 Y 1 B ARG 261 ? B ARG 172 
453  1 Y 1 B ASP 262 ? B ASP 173 
454  1 Y 1 B PRO 263 ? B PRO 174 
455  1 Y 1 B PRO 264 ? B PRO 175 
456  1 Y 1 B LYS 265 ? B LYS 176 
457  1 Y 1 B ASP 266 ? B ASP 177 
458  1 Y 1 B PRO 267 ? B PRO 178 
459  1 Y 1 B SER 268 ? B SER 179 
460  1 Y 1 B SER 269 ? B SER 180 
461  1 Y 1 B ALA 270 ? B ALA 181 
462  1 Y 1 B LYS 271 ? B LYS 182 
463  1 Y 1 B SER 272 ? B SER 183 
464  1 Y 1 B ARG 273 ? B ARG 184 
465  1 Y 1 B LEU 274 ? B LEU 185 
466  1 Y 1 B GLN 275 ? B GLN 186 
467  1 Y 1 B THR 276 ? B THR 187 
468  1 Y 1 B ALA 277 ? B ALA 188 
469  1 Y 1 B PRO 278 ? B PRO 189 
470  1 Y 1 B VAL 279 ? B VAL 190 
471  1 Y 1 B PRO 280 ? B PRO 191 
472  1 Y 1 B MET 281 ? B MET 192 
473  1 Y 1 B PRO 282 ? B PRO 193 
474  1 Y 1 B ASP 283 ? B ASP 194 
475  1 Y 1 B LEU 284 ? B LEU 195 
476  1 Y 1 B LYS 285 ? B LYS 196 
477  1 Y 1 B ASN 286 ? B ASN 197 
478  1 Y 1 B VAL 287 ? B VAL 198 
479  1 Y 1 B LYS 288 ? B LYS 199 
480  1 Y 1 B SER 289 ? B SER 200 
481  1 Y 1 B LYS 290 ? B LYS 201 
482  1 Y 1 B ILE 291 ? B ILE 202 
483  1 Y 1 B GLY 292 ? B GLY 203 
484  1 Y 1 B SER 293 ? B SER 204 
485  1 Y 1 B THR 294 ? B THR 205 
486  1 Y 1 B GLU 295 ? B GLU 206 
487  1 Y 1 B ASN 296 ? B ASN 207 
488  1 Y 1 B LEU 297 ? B LEU 208 
489  1 Y 1 B LYS 298 ? B LYS 209 
490  1 Y 1 B HIS 299 ? B HIS 210 
491  1 Y 1 B GLN 300 ? B GLN 211 
492  1 Y 1 B PRO 301 ? B PRO 212 
493  1 Y 1 B GLY 302 ? B GLY 213 
494  1 Y 1 B GLY 303 ? B GLY 214 
495  1 Y 1 B GLY 304 ? B GLY 215 
496  1 Y 1 B LYS 305 ? B LYS 216 
497  1 Y 1 B VAL 306 ? B VAL 217 
498  1 Y 1 B ARG 379 ? B ARG 290 
499  1 Y 1 B GLU 380 ? B GLU 291 
500  1 Y 1 B ASN 381 ? B ASN 292 
501  1 Y 1 B ALA 382 ? B ALA 293 
502  1 Y 1 B LYS 383 ? B LYS 294 
503  1 Y 1 B ALA 384 ? B ALA 295 
504  1 Y 1 B LYS 385 ? B LYS 296 
505  1 Y 1 B THR 386 ? B THR 297 
506  1 Y 1 B ASP 387 ? B ASP 298 
507  1 Y 1 B HIS 388 ? B HIS 299 
508  1 Y 1 B GLY 389 ? B GLY 300 
509  1 Y 1 B ALA 390 ? B ALA 301 
510  1 Y 1 B GLU 391 ? B GLU 302 
511  1 Y 1 B ILE 392 ? B ILE 303 
512  1 Y 1 B VAL 393 ? B VAL 304 
513  1 Y 1 B TYR 394 ? B TYR 305 
514  1 Y 1 B LYS 395 ? B LYS 306 
515  1 Y 1 B ASP 396 ? B ASP 307 
516  1 Y 1 B PRO 397 ? B PRO 308 
517  1 Y 1 B VAL 398 ? B VAL 309 
518  1 Y 1 B VAL 399 ? B VAL 310 
519  1 Y 1 B ASP 400 ? B ASP 311 
520  1 Y 1 B GLY 401 ? B GLY 312 
521  1 Y 1 B ASP 402 ? B ASP 313 
522  1 Y 1 B ASP 403 ? B ASP 314 
523  1 Y 1 B ASP 404 ? B ASP 315 
524  1 Y 1 B PRO 405 ? B PRO 316 
525  1 Y 1 B ARG 406 ? B ARG 317 
526  1 Y 1 B HIS 407 ? B HIS 318 
527  1 Y 1 B LEU 408 ? B LEU 319 
528  1 Y 1 B SER 409 ? B SER 320 
529  1 Y 1 B ASN 410 ? B ASN 321 
530  1 Y 1 B VAL 411 ? B VAL 322 
531  1 Y 1 B SER 412 ? B SER 323 
532  1 Y 1 B SER 413 ? B SER 324 
533  1 Y 1 B THR 414 ? B THR 325 
534  1 Y 1 B GLY 415 ? B GLY 326 
535  1 Y 1 B SER 416 ? B SER 327 
536  1 Y 1 B ILE 417 ? B ILE 328 
537  1 Y 1 B ASP 418 ? B ASP 329 
538  1 Y 1 B MET 419 ? B MET 330 
539  1 Y 1 B VAL 420 ? B VAL 331 
540  1 Y 1 B ASP 421 ? B ASP 332 
541  1 Y 1 B SER 422 ? B SER 333 
542  1 Y 1 B PRO 423 ? B PRO 334 
543  1 Y 1 B GLN 424 ? B GLN 335 
544  1 Y 1 B LEU 425 ? B LEU 336 
545  1 Y 1 B ALA 426 ? B ALA 337 
546  1 Y 1 B THR 427 ? B THR 338 
547  1 Y 1 B LEU 428 ? B LEU 339 
548  1 Y 1 B ALA 429 ? B ALA 340 
549  1 Y 1 B ASP 430 ? B ASP 341 
550  1 Y 1 B GLU 431 ? B GLU 342 
551  1 Y 1 B VAL 432 ? B VAL 343 
552  1 Y 1 B SER 433 ? B SER 344 
553  1 Y 1 B ALA 434 ? B ALA 345 
554  1 Y 1 B SER 435 ? B SER 346 
555  1 Y 1 B LEU 436 ? B LEU 347 
556  1 Y 1 B ALA 437 ? B ALA 348 
557  1 Y 1 B LYS 438 ? B LYS 349 
558  1 Y 1 B GLN 439 ? B GLN 350 
559  1 Y 1 B GLY 440 ? B GLY 351 
560  1 Y 1 B LEU 441 ? B LEU 352 
561  1 Y 1 C MET 90  ? C MET 1   
562  1 Y 1 C ALA 91  ? C ALA 2   
563  1 Y 1 C GLU 92  ? C GLU 3   
564  1 Y 1 C PRO 93  ? C PRO 4   
565  1 Y 1 C ARG 94  ? C ARG 5   
566  1 Y 1 C GLN 95  ? C GLN 6   
567  1 Y 1 C GLU 96  ? C GLU 7   
568  1 Y 1 C PHE 97  ? C PHE 8   
569  1 Y 1 C GLU 98  ? C GLU 9   
570  1 Y 1 C VAL 99  ? C VAL 10  
571  1 Y 1 C MET 100 ? C MET 11  
572  1 Y 1 C GLU 101 ? C GLU 12  
573  1 Y 1 C ASP 102 ? C ASP 13  
574  1 Y 1 C HIS 103 ? C HIS 14  
575  1 Y 1 C ALA 104 ? C ALA 15  
576  1 Y 1 C GLY 105 ? C GLY 16  
577  1 Y 1 C THR 106 ? C THR 17  
578  1 Y 1 C TYR 107 ? C TYR 18  
579  1 Y 1 C GLY 108 ? C GLY 19  
580  1 Y 1 C LEU 109 ? C LEU 20  
581  1 Y 1 C GLY 110 ? C GLY 21  
582  1 Y 1 C ASP 111 ? C ASP 22  
583  1 Y 1 C ARG 112 ? C ARG 23  
584  1 Y 1 C LYS 113 ? C LYS 24  
585  1 Y 1 C ASP 114 ? C ASP 25  
586  1 Y 1 C GLN 115 ? C GLN 26  
587  1 Y 1 C GLY 116 ? C GLY 27  
588  1 Y 1 C GLY 117 ? C GLY 28  
589  1 Y 1 C TYR 118 ? C TYR 29  
590  1 Y 1 C THR 119 ? C THR 30  
591  1 Y 1 C MET 120 ? C MET 31  
592  1 Y 1 C HIS 121 ? C HIS 32  
593  1 Y 1 C GLN 122 ? C GLN 33  
594  1 Y 1 C ASP 123 ? C ASP 34  
595  1 Y 1 C GLN 124 ? C GLN 35  
596  1 Y 1 C GLU 125 ? C GLU 36  
597  1 Y 1 C GLY 126 ? C GLY 37  
598  1 Y 1 C ASP 127 ? C ASP 38  
599  1 Y 1 C THR 128 ? C THR 39  
600  1 Y 1 C ASP 129 ? C ASP 40  
601  1 Y 1 C ALA 130 ? C ALA 41  
602  1 Y 1 C GLY 131 ? C GLY 42  
603  1 Y 1 C LEU 132 ? C LEU 43  
604  1 Y 1 C LYS 133 ? C LYS 44  
605  1 Y 1 C ALA 134 ? C ALA 45  
606  1 Y 1 C GLU 135 ? C GLU 46  
607  1 Y 1 C GLU 136 ? C GLU 47  
608  1 Y 1 C ALA 137 ? C ALA 48  
609  1 Y 1 C GLY 138 ? C GLY 49  
610  1 Y 1 C ILE 139 ? C ILE 50  
611  1 Y 1 C GLY 140 ? C GLY 51  
612  1 Y 1 C ASP 141 ? C ASP 52  
613  1 Y 1 C THR 142 ? C THR 53  
614  1 Y 1 C PRO 143 ? C PRO 54  
615  1 Y 1 C SER 144 ? C SER 55  
616  1 Y 1 C LEU 145 ? C LEU 56  
617  1 Y 1 C GLU 146 ? C GLU 57  
618  1 Y 1 C ASP 147 ? C ASP 58  
619  1 Y 1 C GLU 148 ? C GLU 59  
620  1 Y 1 C ALA 149 ? C ALA 60  
621  1 Y 1 C ALA 150 ? C ALA 61  
622  1 Y 1 C GLY 151 ? C GLY 62  
623  1 Y 1 C HIS 152 ? C HIS 63  
624  1 Y 1 C VAL 153 ? C VAL 64  
625  1 Y 1 C THR 154 ? C THR 65  
626  1 Y 1 C GLN 155 ? C GLN 66  
627  1 Y 1 C ALA 156 ? C ALA 67  
628  1 Y 1 C ARG 157 ? C ARG 68  
629  1 Y 1 C MET 158 ? C MET 69  
630  1 Y 1 C VAL 159 ? C VAL 70  
631  1 Y 1 C SER 160 ? C SER 71  
632  1 Y 1 C LYS 161 ? C LYS 72  
633  1 Y 1 C SER 162 ? C SER 73  
634  1 Y 1 C LYS 163 ? C LYS 74  
635  1 Y 1 C ASP 164 ? C ASP 75  
636  1 Y 1 C GLY 165 ? C GLY 76  
637  1 Y 1 C THR 166 ? C THR 77  
638  1 Y 1 C GLY 167 ? C GLY 78  
639  1 Y 1 C SER 168 ? C SER 79  
640  1 Y 1 C ASP 169 ? C ASP 80  
641  1 Y 1 C ASP 170 ? C ASP 81  
642  1 Y 1 C LYS 171 ? C LYS 82  
643  1 Y 1 C LYS 172 ? C LYS 83  
644  1 Y 1 C ALA 173 ? C ALA 84  
645  1 Y 1 C LYS 174 ? C LYS 85  
646  1 Y 1 C GLY 175 ? C GLY 86  
647  1 Y 1 C ALA 176 ? C ALA 87  
648  1 Y 1 C ASP 177 ? C ASP 88  
649  1 Y 1 C GLY 178 ? C GLY 89  
650  1 Y 1 C LYS 179 ? C LYS 90  
651  1 Y 1 C THR 180 ? C THR 91  
652  1 Y 1 C LYS 181 ? C LYS 92  
653  1 Y 1 C ILE 182 ? C ILE 93  
654  1 Y 1 C ALA 183 ? C ALA 94  
655  1 Y 1 C THR 184 ? C THR 95  
656  1 Y 1 C PRO 185 ? C PRO 96  
657  1 Y 1 C ARG 186 ? C ARG 97  
658  1 Y 1 C GLY 187 ? C GLY 98  
659  1 Y 1 C ALA 188 ? C ALA 99  
660  1 Y 1 C ALA 189 ? C ALA 100 
661  1 Y 1 C PRO 190 ? C PRO 101 
662  1 Y 1 C PRO 191 ? C PRO 102 
663  1 Y 1 C GLY 192 ? C GLY 103 
664  1 Y 1 C GLN 193 ? C GLN 104 
665  1 Y 1 C LYS 194 ? C LYS 105 
666  1 Y 1 C GLY 195 ? C GLY 106 
667  1 Y 1 C GLN 196 ? C GLN 107 
668  1 Y 1 C ALA 197 ? C ALA 108 
669  1 Y 1 C ASN 198 ? C ASN 109 
670  1 Y 1 C ALA 199 ? C ALA 110 
671  1 Y 1 C THR 200 ? C THR 111 
672  1 Y 1 C ARG 201 ? C ARG 112 
673  1 Y 1 C ILE 202 ? C ILE 113 
674  1 Y 1 C PRO 203 ? C PRO 114 
675  1 Y 1 C ALA 204 ? C ALA 115 
676  1 Y 1 C LYS 205 ? C LYS 116 
677  1 Y 1 C THR 206 ? C THR 117 
678  1 Y 1 C PRO 207 ? C PRO 118 
679  1 Y 1 C PRO 208 ? C PRO 119 
680  1 Y 1 C ALA 209 ? C ALA 120 
681  1 Y 1 C PRO 210 ? C PRO 121 
682  1 Y 1 C LYS 211 ? C LYS 122 
683  1 Y 1 C ASP 212 ? C ASP 123 
684  1 Y 1 C PRO 213 ? C PRO 124 
685  1 Y 1 C PRO 214 ? C PRO 125 
686  1 Y 1 C SER 215 ? C SER 126 
687  1 Y 1 C SER 216 ? C SER 127 
688  1 Y 1 C GLY 217 ? C GLY 128 
689  1 Y 1 C GLU 218 ? C GLU 129 
690  1 Y 1 C PRO 219 ? C PRO 130 
691  1 Y 1 C PRO 220 ? C PRO 131 
692  1 Y 1 C LYS 221 ? C LYS 132 
693  1 Y 1 C SER 222 ? C SER 133 
694  1 Y 1 C GLY 223 ? C GLY 134 
695  1 Y 1 C ASP 224 ? C ASP 135 
696  1 Y 1 C ARG 225 ? C ARG 136 
697  1 Y 1 C SER 226 ? C SER 137 
698  1 Y 1 C GLY 227 ? C GLY 138 
699  1 Y 1 C TYR 228 ? C TYR 139 
700  1 Y 1 C SER 229 ? C SER 140 
701  1 Y 1 C SER 230 ? C SER 141 
702  1 Y 1 C PRO 231 ? C PRO 142 
703  1 Y 1 C GLY 232 ? C GLY 143 
704  1 Y 1 C ASP 233 ? C ASP 144 
705  1 Y 1 C PRO 234 ? C PRO 145 
706  1 Y 1 C GLY 235 ? C GLY 146 
707  1 Y 1 C ASP 236 ? C ASP 147 
708  1 Y 1 C PRO 237 ? C PRO 148 
709  1 Y 1 C GLY 238 ? C GLY 149 
710  1 Y 1 C SER 239 ? C SER 150 
711  1 Y 1 C ARG 240 ? C ARG 151 
712  1 Y 1 C SER 241 ? C SER 152 
713  1 Y 1 C ARG 242 ? C ARG 153 
714  1 Y 1 C ASP 243 ? C ASP 154 
715  1 Y 1 C PRO 244 ? C PRO 155 
716  1 Y 1 C ASP 245 ? C ASP 156 
717  1 Y 1 C LEU 246 ? C LEU 157 
718  1 Y 1 C PRO 247 ? C PRO 158 
719  1 Y 1 C ASP 248 ? C ASP 159 
720  1 Y 1 C PRO 249 ? C PRO 160 
721  1 Y 1 C PRO 250 ? C PRO 161 
722  1 Y 1 C THR 251 ? C THR 162 
723  1 Y 1 C ARG 252 ? C ARG 163 
724  1 Y 1 C GLU 253 ? C GLU 164 
725  1 Y 1 C PRO 254 ? C PRO 165 
726  1 Y 1 C LYS 255 ? C LYS 166 
727  1 Y 1 C LYS 256 ? C LYS 167 
728  1 Y 1 C VAL 257 ? C VAL 168 
729  1 Y 1 C ALA 258 ? C ALA 169 
730  1 Y 1 C VAL 259 ? C VAL 170 
731  1 Y 1 C VAL 260 ? C VAL 171 
732  1 Y 1 C ARG 261 ? C ARG 172 
733  1 Y 1 C ASP 262 ? C ASP 173 
734  1 Y 1 C PRO 263 ? C PRO 174 
735  1 Y 1 C PRO 264 ? C PRO 175 
736  1 Y 1 C LYS 265 ? C LYS 176 
737  1 Y 1 C ASP 266 ? C ASP 177 
738  1 Y 1 C PRO 267 ? C PRO 178 
739  1 Y 1 C SER 268 ? C SER 179 
740  1 Y 1 C SER 269 ? C SER 180 
741  1 Y 1 C ALA 270 ? C ALA 181 
742  1 Y 1 C LYS 271 ? C LYS 182 
743  1 Y 1 C SER 272 ? C SER 183 
744  1 Y 1 C ARG 273 ? C ARG 184 
745  1 Y 1 C LEU 274 ? C LEU 185 
746  1 Y 1 C GLN 275 ? C GLN 186 
747  1 Y 1 C THR 276 ? C THR 187 
748  1 Y 1 C ALA 277 ? C ALA 188 
749  1 Y 1 C PRO 278 ? C PRO 189 
750  1 Y 1 C VAL 279 ? C VAL 190 
751  1 Y 1 C PRO 280 ? C PRO 191 
752  1 Y 1 C MET 281 ? C MET 192 
753  1 Y 1 C PRO 282 ? C PRO 193 
754  1 Y 1 C ASP 283 ? C ASP 194 
755  1 Y 1 C LEU 284 ? C LEU 195 
756  1 Y 1 C LYS 285 ? C LYS 196 
757  1 Y 1 C ASN 286 ? C ASN 197 
758  1 Y 1 C VAL 287 ? C VAL 198 
759  1 Y 1 C LYS 288 ? C LYS 199 
760  1 Y 1 C SER 289 ? C SER 200 
761  1 Y 1 C LYS 290 ? C LYS 201 
762  1 Y 1 C ILE 291 ? C ILE 202 
763  1 Y 1 C GLY 292 ? C GLY 203 
764  1 Y 1 C SER 293 ? C SER 204 
765  1 Y 1 C THR 294 ? C THR 205 
766  1 Y 1 C GLU 295 ? C GLU 206 
767  1 Y 1 C ASN 296 ? C ASN 207 
768  1 Y 1 C LEU 297 ? C LEU 208 
769  1 Y 1 C LYS 298 ? C LYS 209 
770  1 Y 1 C HIS 299 ? C HIS 210 
771  1 Y 1 C GLN 300 ? C GLN 211 
772  1 Y 1 C PRO 301 ? C PRO 212 
773  1 Y 1 C GLY 302 ? C GLY 213 
774  1 Y 1 C GLY 303 ? C GLY 214 
775  1 Y 1 C GLY 304 ? C GLY 215 
776  1 Y 1 C LYS 305 ? C LYS 216 
777  1 Y 1 C VAL 306 ? C VAL 217 
778  1 Y 1 C ARG 379 ? C ARG 290 
779  1 Y 1 C GLU 380 ? C GLU 291 
780  1 Y 1 C ASN 381 ? C ASN 292 
781  1 Y 1 C ALA 382 ? C ALA 293 
782  1 Y 1 C LYS 383 ? C LYS 294 
783  1 Y 1 C ALA 384 ? C ALA 295 
784  1 Y 1 C LYS 385 ? C LYS 296 
785  1 Y 1 C THR 386 ? C THR 297 
786  1 Y 1 C ASP 387 ? C ASP 298 
787  1 Y 1 C HIS 388 ? C HIS 299 
788  1 Y 1 C GLY 389 ? C GLY 300 
789  1 Y 1 C ALA 390 ? C ALA 301 
790  1 Y 1 C GLU 391 ? C GLU 302 
791  1 Y 1 C ILE 392 ? C ILE 303 
792  1 Y 1 C VAL 393 ? C VAL 304 
793  1 Y 1 C TYR 394 ? C TYR 305 
794  1 Y 1 C LYS 395 ? C LYS 306 
795  1 Y 1 C ASP 396 ? C ASP 307 
796  1 Y 1 C PRO 397 ? C PRO 308 
797  1 Y 1 C VAL 398 ? C VAL 309 
798  1 Y 1 C VAL 399 ? C VAL 310 
799  1 Y 1 C ASP 400 ? C ASP 311 
800  1 Y 1 C GLY 401 ? C GLY 312 
801  1 Y 1 C ASP 402 ? C ASP 313 
802  1 Y 1 C ASP 403 ? C ASP 314 
803  1 Y 1 C ASP 404 ? C ASP 315 
804  1 Y 1 C PRO 405 ? C PRO 316 
805  1 Y 1 C ARG 406 ? C ARG 317 
806  1 Y 1 C HIS 407 ? C HIS 318 
807  1 Y 1 C LEU 408 ? C LEU 319 
808  1 Y 1 C SER 409 ? C SER 320 
809  1 Y 1 C ASN 410 ? C ASN 321 
810  1 Y 1 C VAL 411 ? C VAL 322 
811  1 Y 1 C SER 412 ? C SER 323 
812  1 Y 1 C SER 413 ? C SER 324 
813  1 Y 1 C THR 414 ? C THR 325 
814  1 Y 1 C GLY 415 ? C GLY 326 
815  1 Y 1 C SER 416 ? C SER 327 
816  1 Y 1 C ILE 417 ? C ILE 328 
817  1 Y 1 C ASP 418 ? C ASP 329 
818  1 Y 1 C MET 419 ? C MET 330 
819  1 Y 1 C VAL 420 ? C VAL 331 
820  1 Y 1 C ASP 421 ? C ASP 332 
821  1 Y 1 C SER 422 ? C SER 333 
822  1 Y 1 C PRO 423 ? C PRO 334 
823  1 Y 1 C GLN 424 ? C GLN 335 
824  1 Y 1 C LEU 425 ? C LEU 336 
825  1 Y 1 C ALA 426 ? C ALA 337 
826  1 Y 1 C THR 427 ? C THR 338 
827  1 Y 1 C LEU 428 ? C LEU 339 
828  1 Y 1 C ALA 429 ? C ALA 340 
829  1 Y 1 C ASP 430 ? C ASP 341 
830  1 Y 1 C GLU 431 ? C GLU 342 
831  1 Y 1 C VAL 432 ? C VAL 343 
832  1 Y 1 C SER 433 ? C SER 344 
833  1 Y 1 C ALA 434 ? C ALA 345 
834  1 Y 1 C SER 435 ? C SER 346 
835  1 Y 1 C LEU 436 ? C LEU 347 
836  1 Y 1 C ALA 437 ? C ALA 348 
837  1 Y 1 C LYS 438 ? C LYS 349 
838  1 Y 1 C GLN 439 ? C GLN 350 
839  1 Y 1 C GLY 440 ? C GLY 351 
840  1 Y 1 C LEU 441 ? C LEU 352 
841  1 Y 1 D MET 90  ? D MET 1   
842  1 Y 1 D ALA 91  ? D ALA 2   
843  1 Y 1 D GLU 92  ? D GLU 3   
844  1 Y 1 D PRO 93  ? D PRO 4   
845  1 Y 1 D ARG 94  ? D ARG 5   
846  1 Y 1 D GLN 95  ? D GLN 6   
847  1 Y 1 D GLU 96  ? D GLU 7   
848  1 Y 1 D PHE 97  ? D PHE 8   
849  1 Y 1 D GLU 98  ? D GLU 9   
850  1 Y 1 D VAL 99  ? D VAL 10  
851  1 Y 1 D MET 100 ? D MET 11  
852  1 Y 1 D GLU 101 ? D GLU 12  
853  1 Y 1 D ASP 102 ? D ASP 13  
854  1 Y 1 D HIS 103 ? D HIS 14  
855  1 Y 1 D ALA 104 ? D ALA 15  
856  1 Y 1 D GLY 105 ? D GLY 16  
857  1 Y 1 D THR 106 ? D THR 17  
858  1 Y 1 D TYR 107 ? D TYR 18  
859  1 Y 1 D GLY 108 ? D GLY 19  
860  1 Y 1 D LEU 109 ? D LEU 20  
861  1 Y 1 D GLY 110 ? D GLY 21  
862  1 Y 1 D ASP 111 ? D ASP 22  
863  1 Y 1 D ARG 112 ? D ARG 23  
864  1 Y 1 D LYS 113 ? D LYS 24  
865  1 Y 1 D ASP 114 ? D ASP 25  
866  1 Y 1 D GLN 115 ? D GLN 26  
867  1 Y 1 D GLY 116 ? D GLY 27  
868  1 Y 1 D GLY 117 ? D GLY 28  
869  1 Y 1 D TYR 118 ? D TYR 29  
870  1 Y 1 D THR 119 ? D THR 30  
871  1 Y 1 D MET 120 ? D MET 31  
872  1 Y 1 D HIS 121 ? D HIS 32  
873  1 Y 1 D GLN 122 ? D GLN 33  
874  1 Y 1 D ASP 123 ? D ASP 34  
875  1 Y 1 D GLN 124 ? D GLN 35  
876  1 Y 1 D GLU 125 ? D GLU 36  
877  1 Y 1 D GLY 126 ? D GLY 37  
878  1 Y 1 D ASP 127 ? D ASP 38  
879  1 Y 1 D THR 128 ? D THR 39  
880  1 Y 1 D ASP 129 ? D ASP 40  
881  1 Y 1 D ALA 130 ? D ALA 41  
882  1 Y 1 D GLY 131 ? D GLY 42  
883  1 Y 1 D LEU 132 ? D LEU 43  
884  1 Y 1 D LYS 133 ? D LYS 44  
885  1 Y 1 D ALA 134 ? D ALA 45  
886  1 Y 1 D GLU 135 ? D GLU 46  
887  1 Y 1 D GLU 136 ? D GLU 47  
888  1 Y 1 D ALA 137 ? D ALA 48  
889  1 Y 1 D GLY 138 ? D GLY 49  
890  1 Y 1 D ILE 139 ? D ILE 50  
891  1 Y 1 D GLY 140 ? D GLY 51  
892  1 Y 1 D ASP 141 ? D ASP 52  
893  1 Y 1 D THR 142 ? D THR 53  
894  1 Y 1 D PRO 143 ? D PRO 54  
895  1 Y 1 D SER 144 ? D SER 55  
896  1 Y 1 D LEU 145 ? D LEU 56  
897  1 Y 1 D GLU 146 ? D GLU 57  
898  1 Y 1 D ASP 147 ? D ASP 58  
899  1 Y 1 D GLU 148 ? D GLU 59  
900  1 Y 1 D ALA 149 ? D ALA 60  
901  1 Y 1 D ALA 150 ? D ALA 61  
902  1 Y 1 D GLY 151 ? D GLY 62  
903  1 Y 1 D HIS 152 ? D HIS 63  
904  1 Y 1 D VAL 153 ? D VAL 64  
905  1 Y 1 D THR 154 ? D THR 65  
906  1 Y 1 D GLN 155 ? D GLN 66  
907  1 Y 1 D ALA 156 ? D ALA 67  
908  1 Y 1 D ARG 157 ? D ARG 68  
909  1 Y 1 D MET 158 ? D MET 69  
910  1 Y 1 D VAL 159 ? D VAL 70  
911  1 Y 1 D SER 160 ? D SER 71  
912  1 Y 1 D LYS 161 ? D LYS 72  
913  1 Y 1 D SER 162 ? D SER 73  
914  1 Y 1 D LYS 163 ? D LYS 74  
915  1 Y 1 D ASP 164 ? D ASP 75  
916  1 Y 1 D GLY 165 ? D GLY 76  
917  1 Y 1 D THR 166 ? D THR 77  
918  1 Y 1 D GLY 167 ? D GLY 78  
919  1 Y 1 D SER 168 ? D SER 79  
920  1 Y 1 D ASP 169 ? D ASP 80  
921  1 Y 1 D ASP 170 ? D ASP 81  
922  1 Y 1 D LYS 171 ? D LYS 82  
923  1 Y 1 D LYS 172 ? D LYS 83  
924  1 Y 1 D ALA 173 ? D ALA 84  
925  1 Y 1 D LYS 174 ? D LYS 85  
926  1 Y 1 D GLY 175 ? D GLY 86  
927  1 Y 1 D ALA 176 ? D ALA 87  
928  1 Y 1 D ASP 177 ? D ASP 88  
929  1 Y 1 D GLY 178 ? D GLY 89  
930  1 Y 1 D LYS 179 ? D LYS 90  
931  1 Y 1 D THR 180 ? D THR 91  
932  1 Y 1 D LYS 181 ? D LYS 92  
933  1 Y 1 D ILE 182 ? D ILE 93  
934  1 Y 1 D ALA 183 ? D ALA 94  
935  1 Y 1 D THR 184 ? D THR 95  
936  1 Y 1 D PRO 185 ? D PRO 96  
937  1 Y 1 D ARG 186 ? D ARG 97  
938  1 Y 1 D GLY 187 ? D GLY 98  
939  1 Y 1 D ALA 188 ? D ALA 99  
940  1 Y 1 D ALA 189 ? D ALA 100 
941  1 Y 1 D PRO 190 ? D PRO 101 
942  1 Y 1 D PRO 191 ? D PRO 102 
943  1 Y 1 D GLY 192 ? D GLY 103 
944  1 Y 1 D GLN 193 ? D GLN 104 
945  1 Y 1 D LYS 194 ? D LYS 105 
946  1 Y 1 D GLY 195 ? D GLY 106 
947  1 Y 1 D GLN 196 ? D GLN 107 
948  1 Y 1 D ALA 197 ? D ALA 108 
949  1 Y 1 D ASN 198 ? D ASN 109 
950  1 Y 1 D ALA 199 ? D ALA 110 
951  1 Y 1 D THR 200 ? D THR 111 
952  1 Y 1 D ARG 201 ? D ARG 112 
953  1 Y 1 D ILE 202 ? D ILE 113 
954  1 Y 1 D PRO 203 ? D PRO 114 
955  1 Y 1 D ALA 204 ? D ALA 115 
956  1 Y 1 D LYS 205 ? D LYS 116 
957  1 Y 1 D THR 206 ? D THR 117 
958  1 Y 1 D PRO 207 ? D PRO 118 
959  1 Y 1 D PRO 208 ? D PRO 119 
960  1 Y 1 D ALA 209 ? D ALA 120 
961  1 Y 1 D PRO 210 ? D PRO 121 
962  1 Y 1 D LYS 211 ? D LYS 122 
963  1 Y 1 D ASP 212 ? D ASP 123 
964  1 Y 1 D PRO 213 ? D PRO 124 
965  1 Y 1 D PRO 214 ? D PRO 125 
966  1 Y 1 D SER 215 ? D SER 126 
967  1 Y 1 D SER 216 ? D SER 127 
968  1 Y 1 D GLY 217 ? D GLY 128 
969  1 Y 1 D GLU 218 ? D GLU 129 
970  1 Y 1 D PRO 219 ? D PRO 130 
971  1 Y 1 D PRO 220 ? D PRO 131 
972  1 Y 1 D LYS 221 ? D LYS 132 
973  1 Y 1 D SER 222 ? D SER 133 
974  1 Y 1 D GLY 223 ? D GLY 134 
975  1 Y 1 D ASP 224 ? D ASP 135 
976  1 Y 1 D ARG 225 ? D ARG 136 
977  1 Y 1 D SER 226 ? D SER 137 
978  1 Y 1 D GLY 227 ? D GLY 138 
979  1 Y 1 D TYR 228 ? D TYR 139 
980  1 Y 1 D SER 229 ? D SER 140 
981  1 Y 1 D SER 230 ? D SER 141 
982  1 Y 1 D PRO 231 ? D PRO 142 
983  1 Y 1 D GLY 232 ? D GLY 143 
984  1 Y 1 D ASP 233 ? D ASP 144 
985  1 Y 1 D PRO 234 ? D PRO 145 
986  1 Y 1 D GLY 235 ? D GLY 146 
987  1 Y 1 D ASP 236 ? D ASP 147 
988  1 Y 1 D PRO 237 ? D PRO 148 
989  1 Y 1 D GLY 238 ? D GLY 149 
990  1 Y 1 D SER 239 ? D SER 150 
991  1 Y 1 D ARG 240 ? D ARG 151 
992  1 Y 1 D SER 241 ? D SER 152 
993  1 Y 1 D ARG 242 ? D ARG 153 
994  1 Y 1 D ASP 243 ? D ASP 154 
995  1 Y 1 D PRO 244 ? D PRO 155 
996  1 Y 1 D ASP 245 ? D ASP 156 
997  1 Y 1 D LEU 246 ? D LEU 157 
998  1 Y 1 D PRO 247 ? D PRO 158 
999  1 Y 1 D ASP 248 ? D ASP 159 
1000 1 Y 1 D PRO 249 ? D PRO 160 
1001 1 Y 1 D PRO 250 ? D PRO 161 
1002 1 Y 1 D THR 251 ? D THR 162 
1003 1 Y 1 D ARG 252 ? D ARG 163 
1004 1 Y 1 D GLU 253 ? D GLU 164 
1005 1 Y 1 D PRO 254 ? D PRO 165 
1006 1 Y 1 D LYS 255 ? D LYS 166 
1007 1 Y 1 D LYS 256 ? D LYS 167 
1008 1 Y 1 D VAL 257 ? D VAL 168 
1009 1 Y 1 D ALA 258 ? D ALA 169 
1010 1 Y 1 D VAL 259 ? D VAL 170 
1011 1 Y 1 D VAL 260 ? D VAL 171 
1012 1 Y 1 D ARG 261 ? D ARG 172 
1013 1 Y 1 D ASP 262 ? D ASP 173 
1014 1 Y 1 D PRO 263 ? D PRO 174 
1015 1 Y 1 D PRO 264 ? D PRO 175 
1016 1 Y 1 D LYS 265 ? D LYS 176 
1017 1 Y 1 D ASP 266 ? D ASP 177 
1018 1 Y 1 D PRO 267 ? D PRO 178 
1019 1 Y 1 D SER 268 ? D SER 179 
1020 1 Y 1 D SER 269 ? D SER 180 
1021 1 Y 1 D ALA 270 ? D ALA 181 
1022 1 Y 1 D LYS 271 ? D LYS 182 
1023 1 Y 1 D SER 272 ? D SER 183 
1024 1 Y 1 D ARG 273 ? D ARG 184 
1025 1 Y 1 D LEU 274 ? D LEU 185 
1026 1 Y 1 D GLN 275 ? D GLN 186 
1027 1 Y 1 D THR 276 ? D THR 187 
1028 1 Y 1 D ALA 277 ? D ALA 188 
1029 1 Y 1 D PRO 278 ? D PRO 189 
1030 1 Y 1 D VAL 279 ? D VAL 190 
1031 1 Y 1 D PRO 280 ? D PRO 191 
1032 1 Y 1 D MET 281 ? D MET 192 
1033 1 Y 1 D PRO 282 ? D PRO 193 
1034 1 Y 1 D ASP 283 ? D ASP 194 
1035 1 Y 1 D LEU 284 ? D LEU 195 
1036 1 Y 1 D LYS 285 ? D LYS 196 
1037 1 Y 1 D ASN 286 ? D ASN 197 
1038 1 Y 1 D VAL 287 ? D VAL 198 
1039 1 Y 1 D LYS 288 ? D LYS 199 
1040 1 Y 1 D SER 289 ? D SER 200 
1041 1 Y 1 D LYS 290 ? D LYS 201 
1042 1 Y 1 D ILE 291 ? D ILE 202 
1043 1 Y 1 D GLY 292 ? D GLY 203 
1044 1 Y 1 D SER 293 ? D SER 204 
1045 1 Y 1 D THR 294 ? D THR 205 
1046 1 Y 1 D GLU 295 ? D GLU 206 
1047 1 Y 1 D ASN 296 ? D ASN 207 
1048 1 Y 1 D LEU 297 ? D LEU 208 
1049 1 Y 1 D LYS 298 ? D LYS 209 
1050 1 Y 1 D HIS 299 ? D HIS 210 
1051 1 Y 1 D GLN 300 ? D GLN 211 
1052 1 Y 1 D PRO 301 ? D PRO 212 
1053 1 Y 1 D GLY 302 ? D GLY 213 
1054 1 Y 1 D GLY 303 ? D GLY 214 
1055 1 Y 1 D GLY 304 ? D GLY 215 
1056 1 Y 1 D LYS 305 ? D LYS 216 
1057 1 Y 1 D VAL 306 ? D VAL 217 
1058 1 Y 1 D ARG 379 ? D ARG 290 
1059 1 Y 1 D GLU 380 ? D GLU 291 
1060 1 Y 1 D ASN 381 ? D ASN 292 
1061 1 Y 1 D ALA 382 ? D ALA 293 
1062 1 Y 1 D LYS 383 ? D LYS 294 
1063 1 Y 1 D ALA 384 ? D ALA 295 
1064 1 Y 1 D LYS 385 ? D LYS 296 
1065 1 Y 1 D THR 386 ? D THR 297 
1066 1 Y 1 D ASP 387 ? D ASP 298 
1067 1 Y 1 D HIS 388 ? D HIS 299 
1068 1 Y 1 D GLY 389 ? D GLY 300 
1069 1 Y 1 D ALA 390 ? D ALA 301 
1070 1 Y 1 D GLU 391 ? D GLU 302 
1071 1 Y 1 D ILE 392 ? D ILE 303 
1072 1 Y 1 D VAL 393 ? D VAL 304 
1073 1 Y 1 D TYR 394 ? D TYR 305 
1074 1 Y 1 D LYS 395 ? D LYS 306 
1075 1 Y 1 D ASP 396 ? D ASP 307 
1076 1 Y 1 D PRO 397 ? D PRO 308 
1077 1 Y 1 D VAL 398 ? D VAL 309 
1078 1 Y 1 D VAL 399 ? D VAL 310 
1079 1 Y 1 D ASP 400 ? D ASP 311 
1080 1 Y 1 D GLY 401 ? D GLY 312 
1081 1 Y 1 D ASP 402 ? D ASP 313 
1082 1 Y 1 D ASP 403 ? D ASP 314 
1083 1 Y 1 D ASP 404 ? D ASP 315 
1084 1 Y 1 D PRO 405 ? D PRO 316 
1085 1 Y 1 D ARG 406 ? D ARG 317 
1086 1 Y 1 D HIS 407 ? D HIS 318 
1087 1 Y 1 D LEU 408 ? D LEU 319 
1088 1 Y 1 D SER 409 ? D SER 320 
1089 1 Y 1 D ASN 410 ? D ASN 321 
1090 1 Y 1 D VAL 411 ? D VAL 322 
1091 1 Y 1 D SER 412 ? D SER 323 
1092 1 Y 1 D SER 413 ? D SER 324 
1093 1 Y 1 D THR 414 ? D THR 325 
1094 1 Y 1 D GLY 415 ? D GLY 326 
1095 1 Y 1 D SER 416 ? D SER 327 
1096 1 Y 1 D ILE 417 ? D ILE 328 
1097 1 Y 1 D ASP 418 ? D ASP 329 
1098 1 Y 1 D MET 419 ? D MET 330 
1099 1 Y 1 D VAL 420 ? D VAL 331 
1100 1 Y 1 D ASP 421 ? D ASP 332 
1101 1 Y 1 D SER 422 ? D SER 333 
1102 1 Y 1 D PRO 423 ? D PRO 334 
1103 1 Y 1 D GLN 424 ? D GLN 335 
1104 1 Y 1 D LEU 425 ? D LEU 336 
1105 1 Y 1 D ALA 426 ? D ALA 337 
1106 1 Y 1 D THR 427 ? D THR 338 
1107 1 Y 1 D LEU 428 ? D LEU 339 
1108 1 Y 1 D ALA 429 ? D ALA 340 
1109 1 Y 1 D ASP 430 ? D ASP 341 
1110 1 Y 1 D GLU 431 ? D GLU 342 
1111 1 Y 1 D VAL 432 ? D VAL 343 
1112 1 Y 1 D SER 433 ? D SER 344 
1113 1 Y 1 D ALA 434 ? D ALA 345 
1114 1 Y 1 D SER 435 ? D SER 346 
1115 1 Y 1 D LEU 436 ? D LEU 347 
1116 1 Y 1 D ALA 437 ? D ALA 348 
1117 1 Y 1 D LYS 438 ? D LYS 349 
1118 1 Y 1 D GLN 439 ? D GLN 350 
1119 1 Y 1 D GLY 440 ? D GLY 351 
1120 1 Y 1 D LEU 441 ? D LEU 352 
1121 1 Y 1 E MET 90  ? E MET 1   
1122 1 Y 1 E ALA 91  ? E ALA 2   
1123 1 Y 1 E GLU 92  ? E GLU 3   
1124 1 Y 1 E PRO 93  ? E PRO 4   
1125 1 Y 1 E ARG 94  ? E ARG 5   
1126 1 Y 1 E GLN 95  ? E GLN 6   
1127 1 Y 1 E GLU 96  ? E GLU 7   
1128 1 Y 1 E PHE 97  ? E PHE 8   
1129 1 Y 1 E GLU 98  ? E GLU 9   
1130 1 Y 1 E VAL 99  ? E VAL 10  
1131 1 Y 1 E MET 100 ? E MET 11  
1132 1 Y 1 E GLU 101 ? E GLU 12  
1133 1 Y 1 E ASP 102 ? E ASP 13  
1134 1 Y 1 E HIS 103 ? E HIS 14  
1135 1 Y 1 E ALA 104 ? E ALA 15  
1136 1 Y 1 E GLY 105 ? E GLY 16  
1137 1 Y 1 E THR 106 ? E THR 17  
1138 1 Y 1 E TYR 107 ? E TYR 18  
1139 1 Y 1 E GLY 108 ? E GLY 19  
1140 1 Y 1 E LEU 109 ? E LEU 20  
1141 1 Y 1 E GLY 110 ? E GLY 21  
1142 1 Y 1 E ASP 111 ? E ASP 22  
1143 1 Y 1 E ARG 112 ? E ARG 23  
1144 1 Y 1 E LYS 113 ? E LYS 24  
1145 1 Y 1 E ASP 114 ? E ASP 25  
1146 1 Y 1 E GLN 115 ? E GLN 26  
1147 1 Y 1 E GLY 116 ? E GLY 27  
1148 1 Y 1 E GLY 117 ? E GLY 28  
1149 1 Y 1 E TYR 118 ? E TYR 29  
1150 1 Y 1 E THR 119 ? E THR 30  
1151 1 Y 1 E MET 120 ? E MET 31  
1152 1 Y 1 E HIS 121 ? E HIS 32  
1153 1 Y 1 E GLN 122 ? E GLN 33  
1154 1 Y 1 E ASP 123 ? E ASP 34  
1155 1 Y 1 E GLN 124 ? E GLN 35  
1156 1 Y 1 E GLU 125 ? E GLU 36  
1157 1 Y 1 E GLY 126 ? E GLY 37  
1158 1 Y 1 E ASP 127 ? E ASP 38  
1159 1 Y 1 E THR 128 ? E THR 39  
1160 1 Y 1 E ASP 129 ? E ASP 40  
1161 1 Y 1 E ALA 130 ? E ALA 41  
1162 1 Y 1 E GLY 131 ? E GLY 42  
1163 1 Y 1 E LEU 132 ? E LEU 43  
1164 1 Y 1 E LYS 133 ? E LYS 44  
1165 1 Y 1 E ALA 134 ? E ALA 45  
1166 1 Y 1 E GLU 135 ? E GLU 46  
1167 1 Y 1 E GLU 136 ? E GLU 47  
1168 1 Y 1 E ALA 137 ? E ALA 48  
1169 1 Y 1 E GLY 138 ? E GLY 49  
1170 1 Y 1 E ILE 139 ? E ILE 50  
1171 1 Y 1 E GLY 140 ? E GLY 51  
1172 1 Y 1 E ASP 141 ? E ASP 52  
1173 1 Y 1 E THR 142 ? E THR 53  
1174 1 Y 1 E PRO 143 ? E PRO 54  
1175 1 Y 1 E SER 144 ? E SER 55  
1176 1 Y 1 E LEU 145 ? E LEU 56  
1177 1 Y 1 E GLU 146 ? E GLU 57  
1178 1 Y 1 E ASP 147 ? E ASP 58  
1179 1 Y 1 E GLU 148 ? E GLU 59  
1180 1 Y 1 E ALA 149 ? E ALA 60  
1181 1 Y 1 E ALA 150 ? E ALA 61  
1182 1 Y 1 E GLY 151 ? E GLY 62  
1183 1 Y 1 E HIS 152 ? E HIS 63  
1184 1 Y 1 E VAL 153 ? E VAL 64  
1185 1 Y 1 E THR 154 ? E THR 65  
1186 1 Y 1 E GLN 155 ? E GLN 66  
1187 1 Y 1 E ALA 156 ? E ALA 67  
1188 1 Y 1 E ARG 157 ? E ARG 68  
1189 1 Y 1 E MET 158 ? E MET 69  
1190 1 Y 1 E VAL 159 ? E VAL 70  
1191 1 Y 1 E SER 160 ? E SER 71  
1192 1 Y 1 E LYS 161 ? E LYS 72  
1193 1 Y 1 E SER 162 ? E SER 73  
1194 1 Y 1 E LYS 163 ? E LYS 74  
1195 1 Y 1 E ASP 164 ? E ASP 75  
1196 1 Y 1 E GLY 165 ? E GLY 76  
1197 1 Y 1 E THR 166 ? E THR 77  
1198 1 Y 1 E GLY 167 ? E GLY 78  
1199 1 Y 1 E SER 168 ? E SER 79  
1200 1 Y 1 E ASP 169 ? E ASP 80  
1201 1 Y 1 E ASP 170 ? E ASP 81  
1202 1 Y 1 E LYS 171 ? E LYS 82  
1203 1 Y 1 E LYS 172 ? E LYS 83  
1204 1 Y 1 E ALA 173 ? E ALA 84  
1205 1 Y 1 E LYS 174 ? E LYS 85  
1206 1 Y 1 E GLY 175 ? E GLY 86  
1207 1 Y 1 E ALA 176 ? E ALA 87  
1208 1 Y 1 E ASP 177 ? E ASP 88  
1209 1 Y 1 E GLY 178 ? E GLY 89  
1210 1 Y 1 E LYS 179 ? E LYS 90  
1211 1 Y 1 E THR 180 ? E THR 91  
1212 1 Y 1 E LYS 181 ? E LYS 92  
1213 1 Y 1 E ILE 182 ? E ILE 93  
1214 1 Y 1 E ALA 183 ? E ALA 94  
1215 1 Y 1 E THR 184 ? E THR 95  
1216 1 Y 1 E PRO 185 ? E PRO 96  
1217 1 Y 1 E ARG 186 ? E ARG 97  
1218 1 Y 1 E GLY 187 ? E GLY 98  
1219 1 Y 1 E ALA 188 ? E ALA 99  
1220 1 Y 1 E ALA 189 ? E ALA 100 
1221 1 Y 1 E PRO 190 ? E PRO 101 
1222 1 Y 1 E PRO 191 ? E PRO 102 
1223 1 Y 1 E GLY 192 ? E GLY 103 
1224 1 Y 1 E GLN 193 ? E GLN 104 
1225 1 Y 1 E LYS 194 ? E LYS 105 
1226 1 Y 1 E GLY 195 ? E GLY 106 
1227 1 Y 1 E GLN 196 ? E GLN 107 
1228 1 Y 1 E ALA 197 ? E ALA 108 
1229 1 Y 1 E ASN 198 ? E ASN 109 
1230 1 Y 1 E ALA 199 ? E ALA 110 
1231 1 Y 1 E THR 200 ? E THR 111 
1232 1 Y 1 E ARG 201 ? E ARG 112 
1233 1 Y 1 E ILE 202 ? E ILE 113 
1234 1 Y 1 E PRO 203 ? E PRO 114 
1235 1 Y 1 E ALA 204 ? E ALA 115 
1236 1 Y 1 E LYS 205 ? E LYS 116 
1237 1 Y 1 E THR 206 ? E THR 117 
1238 1 Y 1 E PRO 207 ? E PRO 118 
1239 1 Y 1 E PRO 208 ? E PRO 119 
1240 1 Y 1 E ALA 209 ? E ALA 120 
1241 1 Y 1 E PRO 210 ? E PRO 121 
1242 1 Y 1 E LYS 211 ? E LYS 122 
1243 1 Y 1 E ASP 212 ? E ASP 123 
1244 1 Y 1 E PRO 213 ? E PRO 124 
1245 1 Y 1 E PRO 214 ? E PRO 125 
1246 1 Y 1 E SER 215 ? E SER 126 
1247 1 Y 1 E SER 216 ? E SER 127 
1248 1 Y 1 E GLY 217 ? E GLY 128 
1249 1 Y 1 E GLU 218 ? E GLU 129 
1250 1 Y 1 E PRO 219 ? E PRO 130 
1251 1 Y 1 E PRO 220 ? E PRO 131 
1252 1 Y 1 E LYS 221 ? E LYS 132 
1253 1 Y 1 E SER 222 ? E SER 133 
1254 1 Y 1 E GLY 223 ? E GLY 134 
1255 1 Y 1 E ASP 224 ? E ASP 135 
1256 1 Y 1 E ARG 225 ? E ARG 136 
1257 1 Y 1 E SER 226 ? E SER 137 
1258 1 Y 1 E GLY 227 ? E GLY 138 
1259 1 Y 1 E TYR 228 ? E TYR 139 
1260 1 Y 1 E SER 229 ? E SER 140 
1261 1 Y 1 E SER 230 ? E SER 141 
1262 1 Y 1 E PRO 231 ? E PRO 142 
1263 1 Y 1 E GLY 232 ? E GLY 143 
1264 1 Y 1 E ASP 233 ? E ASP 144 
1265 1 Y 1 E PRO 234 ? E PRO 145 
1266 1 Y 1 E GLY 235 ? E GLY 146 
1267 1 Y 1 E ASP 236 ? E ASP 147 
1268 1 Y 1 E PRO 237 ? E PRO 148 
1269 1 Y 1 E GLY 238 ? E GLY 149 
1270 1 Y 1 E SER 239 ? E SER 150 
1271 1 Y 1 E ARG 240 ? E ARG 151 
1272 1 Y 1 E SER 241 ? E SER 152 
1273 1 Y 1 E ARG 242 ? E ARG 153 
1274 1 Y 1 E ASP 243 ? E ASP 154 
1275 1 Y 1 E PRO 244 ? E PRO 155 
1276 1 Y 1 E ASP 245 ? E ASP 156 
1277 1 Y 1 E LEU 246 ? E LEU 157 
1278 1 Y 1 E PRO 247 ? E PRO 158 
1279 1 Y 1 E ASP 248 ? E ASP 159 
1280 1 Y 1 E PRO 249 ? E PRO 160 
1281 1 Y 1 E PRO 250 ? E PRO 161 
1282 1 Y 1 E THR 251 ? E THR 162 
1283 1 Y 1 E ARG 252 ? E ARG 163 
1284 1 Y 1 E GLU 253 ? E GLU 164 
1285 1 Y 1 E PRO 254 ? E PRO 165 
1286 1 Y 1 E LYS 255 ? E LYS 166 
1287 1 Y 1 E LYS 256 ? E LYS 167 
1288 1 Y 1 E VAL 257 ? E VAL 168 
1289 1 Y 1 E ALA 258 ? E ALA 169 
1290 1 Y 1 E VAL 259 ? E VAL 170 
1291 1 Y 1 E VAL 260 ? E VAL 171 
1292 1 Y 1 E ARG 261 ? E ARG 172 
1293 1 Y 1 E ASP 262 ? E ASP 173 
1294 1 Y 1 E PRO 263 ? E PRO 174 
1295 1 Y 1 E PRO 264 ? E PRO 175 
1296 1 Y 1 E LYS 265 ? E LYS 176 
1297 1 Y 1 E ASP 266 ? E ASP 177 
1298 1 Y 1 E PRO 267 ? E PRO 178 
1299 1 Y 1 E SER 268 ? E SER 179 
1300 1 Y 1 E SER 269 ? E SER 180 
1301 1 Y 1 E ALA 270 ? E ALA 181 
1302 1 Y 1 E LYS 271 ? E LYS 182 
1303 1 Y 1 E SER 272 ? E SER 183 
1304 1 Y 1 E ARG 273 ? E ARG 184 
1305 1 Y 1 E LEU 274 ? E LEU 185 
1306 1 Y 1 E GLN 275 ? E GLN 186 
1307 1 Y 1 E THR 276 ? E THR 187 
1308 1 Y 1 E ALA 277 ? E ALA 188 
1309 1 Y 1 E PRO 278 ? E PRO 189 
1310 1 Y 1 E VAL 279 ? E VAL 190 
1311 1 Y 1 E PRO 280 ? E PRO 191 
1312 1 Y 1 E MET 281 ? E MET 192 
1313 1 Y 1 E PRO 282 ? E PRO 193 
1314 1 Y 1 E ASP 283 ? E ASP 194 
1315 1 Y 1 E LEU 284 ? E LEU 195 
1316 1 Y 1 E LYS 285 ? E LYS 196 
1317 1 Y 1 E ASN 286 ? E ASN 197 
1318 1 Y 1 E VAL 287 ? E VAL 198 
1319 1 Y 1 E LYS 288 ? E LYS 199 
1320 1 Y 1 E SER 289 ? E SER 200 
1321 1 Y 1 E LYS 290 ? E LYS 201 
1322 1 Y 1 E ILE 291 ? E ILE 202 
1323 1 Y 1 E GLY 292 ? E GLY 203 
1324 1 Y 1 E SER 293 ? E SER 204 
1325 1 Y 1 E THR 294 ? E THR 205 
1326 1 Y 1 E GLU 295 ? E GLU 206 
1327 1 Y 1 E ASN 296 ? E ASN 207 
1328 1 Y 1 E LEU 297 ? E LEU 208 
1329 1 Y 1 E LYS 298 ? E LYS 209 
1330 1 Y 1 E HIS 299 ? E HIS 210 
1331 1 Y 1 E GLN 300 ? E GLN 211 
1332 1 Y 1 E PRO 301 ? E PRO 212 
1333 1 Y 1 E GLY 302 ? E GLY 213 
1334 1 Y 1 E GLY 303 ? E GLY 214 
1335 1 Y 1 E GLY 304 ? E GLY 215 
1336 1 Y 1 E LYS 305 ? E LYS 216 
1337 1 Y 1 E VAL 306 ? E VAL 217 
1338 1 Y 1 E ARG 379 ? E ARG 290 
1339 1 Y 1 E GLU 380 ? E GLU 291 
1340 1 Y 1 E ASN 381 ? E ASN 292 
1341 1 Y 1 E ALA 382 ? E ALA 293 
1342 1 Y 1 E LYS 383 ? E LYS 294 
1343 1 Y 1 E ALA 384 ? E ALA 295 
1344 1 Y 1 E LYS 385 ? E LYS 296 
1345 1 Y 1 E THR 386 ? E THR 297 
1346 1 Y 1 E ASP 387 ? E ASP 298 
1347 1 Y 1 E HIS 388 ? E HIS 299 
1348 1 Y 1 E GLY 389 ? E GLY 300 
1349 1 Y 1 E ALA 390 ? E ALA 301 
1350 1 Y 1 E GLU 391 ? E GLU 302 
1351 1 Y 1 E ILE 392 ? E ILE 303 
1352 1 Y 1 E VAL 393 ? E VAL 304 
1353 1 Y 1 E TYR 394 ? E TYR 305 
1354 1 Y 1 E LYS 395 ? E LYS 306 
1355 1 Y 1 E ASP 396 ? E ASP 307 
1356 1 Y 1 E PRO 397 ? E PRO 308 
1357 1 Y 1 E VAL 398 ? E VAL 309 
1358 1 Y 1 E VAL 399 ? E VAL 310 
1359 1 Y 1 E ASP 400 ? E ASP 311 
1360 1 Y 1 E GLY 401 ? E GLY 312 
1361 1 Y 1 E ASP 402 ? E ASP 313 
1362 1 Y 1 E ASP 403 ? E ASP 314 
1363 1 Y 1 E ASP 404 ? E ASP 315 
1364 1 Y 1 E PRO 405 ? E PRO 316 
1365 1 Y 1 E ARG 406 ? E ARG 317 
1366 1 Y 1 E HIS 407 ? E HIS 318 
1367 1 Y 1 E LEU 408 ? E LEU 319 
1368 1 Y 1 E SER 409 ? E SER 320 
1369 1 Y 1 E ASN 410 ? E ASN 321 
1370 1 Y 1 E VAL 411 ? E VAL 322 
1371 1 Y 1 E SER 412 ? E SER 323 
1372 1 Y 1 E SER 413 ? E SER 324 
1373 1 Y 1 E THR 414 ? E THR 325 
1374 1 Y 1 E GLY 415 ? E GLY 326 
1375 1 Y 1 E SER 416 ? E SER 327 
1376 1 Y 1 E ILE 417 ? E ILE 328 
1377 1 Y 1 E ASP 418 ? E ASP 329 
1378 1 Y 1 E MET 419 ? E MET 330 
1379 1 Y 1 E VAL 420 ? E VAL 331 
1380 1 Y 1 E ASP 421 ? E ASP 332 
1381 1 Y 1 E SER 422 ? E SER 333 
1382 1 Y 1 E PRO 423 ? E PRO 334 
1383 1 Y 1 E GLN 424 ? E GLN 335 
1384 1 Y 1 E LEU 425 ? E LEU 336 
1385 1 Y 1 E ALA 426 ? E ALA 337 
1386 1 Y 1 E THR 427 ? E THR 338 
1387 1 Y 1 E LEU 428 ? E LEU 339 
1388 1 Y 1 E ALA 429 ? E ALA 340 
1389 1 Y 1 E ASP 430 ? E ASP 341 
1390 1 Y 1 E GLU 431 ? E GLU 342 
1391 1 Y 1 E VAL 432 ? E VAL 343 
1392 1 Y 1 E SER 433 ? E SER 344 
1393 1 Y 1 E ALA 434 ? E ALA 345 
1394 1 Y 1 E SER 435 ? E SER 346 
1395 1 Y 1 E LEU 436 ? E LEU 347 
1396 1 Y 1 E ALA 437 ? E ALA 348 
1397 1 Y 1 E LYS 438 ? E LYS 349 
1398 1 Y 1 E GLN 439 ? E GLN 350 
1399 1 Y 1 E GLY 440 ? E GLY 351 
1400 1 Y 1 E LEU 441 ? E LEU 352 
1401 1 Y 1 F MET 90  ? F MET 1   
1402 1 Y 1 F ALA 91  ? F ALA 2   
1403 1 Y 1 F GLU 92  ? F GLU 3   
1404 1 Y 1 F PRO 93  ? F PRO 4   
1405 1 Y 1 F ARG 94  ? F ARG 5   
1406 1 Y 1 F GLN 95  ? F GLN 6   
1407 1 Y 1 F GLU 96  ? F GLU 7   
1408 1 Y 1 F PHE 97  ? F PHE 8   
1409 1 Y 1 F GLU 98  ? F GLU 9   
1410 1 Y 1 F VAL 99  ? F VAL 10  
1411 1 Y 1 F MET 100 ? F MET 11  
1412 1 Y 1 F GLU 101 ? F GLU 12  
1413 1 Y 1 F ASP 102 ? F ASP 13  
1414 1 Y 1 F HIS 103 ? F HIS 14  
1415 1 Y 1 F ALA 104 ? F ALA 15  
1416 1 Y 1 F GLY 105 ? F GLY 16  
1417 1 Y 1 F THR 106 ? F THR 17  
1418 1 Y 1 F TYR 107 ? F TYR 18  
1419 1 Y 1 F GLY 108 ? F GLY 19  
1420 1 Y 1 F LEU 109 ? F LEU 20  
1421 1 Y 1 F GLY 110 ? F GLY 21  
1422 1 Y 1 F ASP 111 ? F ASP 22  
1423 1 Y 1 F ARG 112 ? F ARG 23  
1424 1 Y 1 F LYS 113 ? F LYS 24  
1425 1 Y 1 F ASP 114 ? F ASP 25  
1426 1 Y 1 F GLN 115 ? F GLN 26  
1427 1 Y 1 F GLY 116 ? F GLY 27  
1428 1 Y 1 F GLY 117 ? F GLY 28  
1429 1 Y 1 F TYR 118 ? F TYR 29  
1430 1 Y 1 F THR 119 ? F THR 30  
1431 1 Y 1 F MET 120 ? F MET 31  
1432 1 Y 1 F HIS 121 ? F HIS 32  
1433 1 Y 1 F GLN 122 ? F GLN 33  
1434 1 Y 1 F ASP 123 ? F ASP 34  
1435 1 Y 1 F GLN 124 ? F GLN 35  
1436 1 Y 1 F GLU 125 ? F GLU 36  
1437 1 Y 1 F GLY 126 ? F GLY 37  
1438 1 Y 1 F ASP 127 ? F ASP 38  
1439 1 Y 1 F THR 128 ? F THR 39  
1440 1 Y 1 F ASP 129 ? F ASP 40  
1441 1 Y 1 F ALA 130 ? F ALA 41  
1442 1 Y 1 F GLY 131 ? F GLY 42  
1443 1 Y 1 F LEU 132 ? F LEU 43  
1444 1 Y 1 F LYS 133 ? F LYS 44  
1445 1 Y 1 F ALA 134 ? F ALA 45  
1446 1 Y 1 F GLU 135 ? F GLU 46  
1447 1 Y 1 F GLU 136 ? F GLU 47  
1448 1 Y 1 F ALA 137 ? F ALA 48  
1449 1 Y 1 F GLY 138 ? F GLY 49  
1450 1 Y 1 F ILE 139 ? F ILE 50  
1451 1 Y 1 F GLY 140 ? F GLY 51  
1452 1 Y 1 F ASP 141 ? F ASP 52  
1453 1 Y 1 F THR 142 ? F THR 53  
1454 1 Y 1 F PRO 143 ? F PRO 54  
1455 1 Y 1 F SER 144 ? F SER 55  
1456 1 Y 1 F LEU 145 ? F LEU 56  
1457 1 Y 1 F GLU 146 ? F GLU 57  
1458 1 Y 1 F ASP 147 ? F ASP 58  
1459 1 Y 1 F GLU 148 ? F GLU 59  
1460 1 Y 1 F ALA 149 ? F ALA 60  
1461 1 Y 1 F ALA 150 ? F ALA 61  
1462 1 Y 1 F GLY 151 ? F GLY 62  
1463 1 Y 1 F HIS 152 ? F HIS 63  
1464 1 Y 1 F VAL 153 ? F VAL 64  
1465 1 Y 1 F THR 154 ? F THR 65  
1466 1 Y 1 F GLN 155 ? F GLN 66  
1467 1 Y 1 F ALA 156 ? F ALA 67  
1468 1 Y 1 F ARG 157 ? F ARG 68  
1469 1 Y 1 F MET 158 ? F MET 69  
1470 1 Y 1 F VAL 159 ? F VAL 70  
1471 1 Y 1 F SER 160 ? F SER 71  
1472 1 Y 1 F LYS 161 ? F LYS 72  
1473 1 Y 1 F SER 162 ? F SER 73  
1474 1 Y 1 F LYS 163 ? F LYS 74  
1475 1 Y 1 F ASP 164 ? F ASP 75  
1476 1 Y 1 F GLY 165 ? F GLY 76  
1477 1 Y 1 F THR 166 ? F THR 77  
1478 1 Y 1 F GLY 167 ? F GLY 78  
1479 1 Y 1 F SER 168 ? F SER 79  
1480 1 Y 1 F ASP 169 ? F ASP 80  
1481 1 Y 1 F ASP 170 ? F ASP 81  
1482 1 Y 1 F LYS 171 ? F LYS 82  
1483 1 Y 1 F LYS 172 ? F LYS 83  
1484 1 Y 1 F ALA 173 ? F ALA 84  
1485 1 Y 1 F LYS 174 ? F LYS 85  
1486 1 Y 1 F GLY 175 ? F GLY 86  
1487 1 Y 1 F ALA 176 ? F ALA 87  
1488 1 Y 1 F ASP 177 ? F ASP 88  
1489 1 Y 1 F GLY 178 ? F GLY 89  
1490 1 Y 1 F LYS 179 ? F LYS 90  
1491 1 Y 1 F THR 180 ? F THR 91  
1492 1 Y 1 F LYS 181 ? F LYS 92  
1493 1 Y 1 F ILE 182 ? F ILE 93  
1494 1 Y 1 F ALA 183 ? F ALA 94  
1495 1 Y 1 F THR 184 ? F THR 95  
1496 1 Y 1 F PRO 185 ? F PRO 96  
1497 1 Y 1 F ARG 186 ? F ARG 97  
1498 1 Y 1 F GLY 187 ? F GLY 98  
1499 1 Y 1 F ALA 188 ? F ALA 99  
1500 1 Y 1 F ALA 189 ? F ALA 100 
1501 1 Y 1 F PRO 190 ? F PRO 101 
1502 1 Y 1 F PRO 191 ? F PRO 102 
1503 1 Y 1 F GLY 192 ? F GLY 103 
1504 1 Y 1 F GLN 193 ? F GLN 104 
1505 1 Y 1 F LYS 194 ? F LYS 105 
1506 1 Y 1 F GLY 195 ? F GLY 106 
1507 1 Y 1 F GLN 196 ? F GLN 107 
1508 1 Y 1 F ALA 197 ? F ALA 108 
1509 1 Y 1 F ASN 198 ? F ASN 109 
1510 1 Y 1 F ALA 199 ? F ALA 110 
1511 1 Y 1 F THR 200 ? F THR 111 
1512 1 Y 1 F ARG 201 ? F ARG 112 
1513 1 Y 1 F ILE 202 ? F ILE 113 
1514 1 Y 1 F PRO 203 ? F PRO 114 
1515 1 Y 1 F ALA 204 ? F ALA 115 
1516 1 Y 1 F LYS 205 ? F LYS 116 
1517 1 Y 1 F THR 206 ? F THR 117 
1518 1 Y 1 F PRO 207 ? F PRO 118 
1519 1 Y 1 F PRO 208 ? F PRO 119 
1520 1 Y 1 F ALA 209 ? F ALA 120 
1521 1 Y 1 F PRO 210 ? F PRO 121 
1522 1 Y 1 F LYS 211 ? F LYS 122 
1523 1 Y 1 F ASP 212 ? F ASP 123 
1524 1 Y 1 F PRO 213 ? F PRO 124 
1525 1 Y 1 F PRO 214 ? F PRO 125 
1526 1 Y 1 F SER 215 ? F SER 126 
1527 1 Y 1 F SER 216 ? F SER 127 
1528 1 Y 1 F GLY 217 ? F GLY 128 
1529 1 Y 1 F GLU 218 ? F GLU 129 
1530 1 Y 1 F PRO 219 ? F PRO 130 
1531 1 Y 1 F PRO 220 ? F PRO 131 
1532 1 Y 1 F LYS 221 ? F LYS 132 
1533 1 Y 1 F SER 222 ? F SER 133 
1534 1 Y 1 F GLY 223 ? F GLY 134 
1535 1 Y 1 F ASP 224 ? F ASP 135 
1536 1 Y 1 F ARG 225 ? F ARG 136 
1537 1 Y 1 F SER 226 ? F SER 137 
1538 1 Y 1 F GLY 227 ? F GLY 138 
1539 1 Y 1 F TYR 228 ? F TYR 139 
1540 1 Y 1 F SER 229 ? F SER 140 
1541 1 Y 1 F SER 230 ? F SER 141 
1542 1 Y 1 F PRO 231 ? F PRO 142 
1543 1 Y 1 F GLY 232 ? F GLY 143 
1544 1 Y 1 F ASP 233 ? F ASP 144 
1545 1 Y 1 F PRO 234 ? F PRO 145 
1546 1 Y 1 F GLY 235 ? F GLY 146 
1547 1 Y 1 F ASP 236 ? F ASP 147 
1548 1 Y 1 F PRO 237 ? F PRO 148 
1549 1 Y 1 F GLY 238 ? F GLY 149 
1550 1 Y 1 F SER 239 ? F SER 150 
1551 1 Y 1 F ARG 240 ? F ARG 151 
1552 1 Y 1 F SER 241 ? F SER 152 
1553 1 Y 1 F ARG 242 ? F ARG 153 
1554 1 Y 1 F ASP 243 ? F ASP 154 
1555 1 Y 1 F PRO 244 ? F PRO 155 
1556 1 Y 1 F ASP 245 ? F ASP 156 
1557 1 Y 1 F LEU 246 ? F LEU 157 
1558 1 Y 1 F PRO 247 ? F PRO 158 
1559 1 Y 1 F ASP 248 ? F ASP 159 
1560 1 Y 1 F PRO 249 ? F PRO 160 
1561 1 Y 1 F PRO 250 ? F PRO 161 
1562 1 Y 1 F THR 251 ? F THR 162 
1563 1 Y 1 F ARG 252 ? F ARG 163 
1564 1 Y 1 F GLU 253 ? F GLU 164 
1565 1 Y 1 F PRO 254 ? F PRO 165 
1566 1 Y 1 F LYS 255 ? F LYS 166 
1567 1 Y 1 F LYS 256 ? F LYS 167 
1568 1 Y 1 F VAL 257 ? F VAL 168 
1569 1 Y 1 F ALA 258 ? F ALA 169 
1570 1 Y 1 F VAL 259 ? F VAL 170 
1571 1 Y 1 F VAL 260 ? F VAL 171 
1572 1 Y 1 F ARG 261 ? F ARG 172 
1573 1 Y 1 F ASP 262 ? F ASP 173 
1574 1 Y 1 F PRO 263 ? F PRO 174 
1575 1 Y 1 F PRO 264 ? F PRO 175 
1576 1 Y 1 F LYS 265 ? F LYS 176 
1577 1 Y 1 F ASP 266 ? F ASP 177 
1578 1 Y 1 F PRO 267 ? F PRO 178 
1579 1 Y 1 F SER 268 ? F SER 179 
1580 1 Y 1 F SER 269 ? F SER 180 
1581 1 Y 1 F ALA 270 ? F ALA 181 
1582 1 Y 1 F LYS 271 ? F LYS 182 
1583 1 Y 1 F SER 272 ? F SER 183 
1584 1 Y 1 F ARG 273 ? F ARG 184 
1585 1 Y 1 F LEU 274 ? F LEU 185 
1586 1 Y 1 F GLN 275 ? F GLN 186 
1587 1 Y 1 F THR 276 ? F THR 187 
1588 1 Y 1 F ALA 277 ? F ALA 188 
1589 1 Y 1 F PRO 278 ? F PRO 189 
1590 1 Y 1 F VAL 279 ? F VAL 190 
1591 1 Y 1 F PRO 280 ? F PRO 191 
1592 1 Y 1 F MET 281 ? F MET 192 
1593 1 Y 1 F PRO 282 ? F PRO 193 
1594 1 Y 1 F ASP 283 ? F ASP 194 
1595 1 Y 1 F LEU 284 ? F LEU 195 
1596 1 Y 1 F LYS 285 ? F LYS 196 
1597 1 Y 1 F ASN 286 ? F ASN 197 
1598 1 Y 1 F VAL 287 ? F VAL 198 
1599 1 Y 1 F LYS 288 ? F LYS 199 
1600 1 Y 1 F SER 289 ? F SER 200 
1601 1 Y 1 F LYS 290 ? F LYS 201 
1602 1 Y 1 F ILE 291 ? F ILE 202 
1603 1 Y 1 F GLY 292 ? F GLY 203 
1604 1 Y 1 F SER 293 ? F SER 204 
1605 1 Y 1 F THR 294 ? F THR 205 
1606 1 Y 1 F GLU 295 ? F GLU 206 
1607 1 Y 1 F ASN 296 ? F ASN 207 
1608 1 Y 1 F LEU 297 ? F LEU 208 
1609 1 Y 1 F LYS 298 ? F LYS 209 
1610 1 Y 1 F HIS 299 ? F HIS 210 
1611 1 Y 1 F GLN 300 ? F GLN 211 
1612 1 Y 1 F PRO 301 ? F PRO 212 
1613 1 Y 1 F GLY 302 ? F GLY 213 
1614 1 Y 1 F GLY 303 ? F GLY 214 
1615 1 Y 1 F GLY 304 ? F GLY 215 
1616 1 Y 1 F LYS 305 ? F LYS 216 
1617 1 Y 1 F VAL 306 ? F VAL 217 
1618 1 Y 1 F ARG 379 ? F ARG 290 
1619 1 Y 1 F GLU 380 ? F GLU 291 
1620 1 Y 1 F ASN 381 ? F ASN 292 
1621 1 Y 1 F ALA 382 ? F ALA 293 
1622 1 Y 1 F LYS 383 ? F LYS 294 
1623 1 Y 1 F ALA 384 ? F ALA 295 
1624 1 Y 1 F LYS 385 ? F LYS 296 
1625 1 Y 1 F THR 386 ? F THR 297 
1626 1 Y 1 F ASP 387 ? F ASP 298 
1627 1 Y 1 F HIS 388 ? F HIS 299 
1628 1 Y 1 F GLY 389 ? F GLY 300 
1629 1 Y 1 F ALA 390 ? F ALA 301 
1630 1 Y 1 F GLU 391 ? F GLU 302 
1631 1 Y 1 F ILE 392 ? F ILE 303 
1632 1 Y 1 F VAL 393 ? F VAL 304 
1633 1 Y 1 F TYR 394 ? F TYR 305 
1634 1 Y 1 F LYS 395 ? F LYS 306 
1635 1 Y 1 F ASP 396 ? F ASP 307 
1636 1 Y 1 F PRO 397 ? F PRO 308 
1637 1 Y 1 F VAL 398 ? F VAL 309 
1638 1 Y 1 F VAL 399 ? F VAL 310 
1639 1 Y 1 F ASP 400 ? F ASP 311 
1640 1 Y 1 F GLY 401 ? F GLY 312 
1641 1 Y 1 F ASP 402 ? F ASP 313 
1642 1 Y 1 F ASP 403 ? F ASP 314 
1643 1 Y 1 F ASP 404 ? F ASP 315 
1644 1 Y 1 F PRO 405 ? F PRO 316 
1645 1 Y 1 F ARG 406 ? F ARG 317 
1646 1 Y 1 F HIS 407 ? F HIS 318 
1647 1 Y 1 F LEU 408 ? F LEU 319 
1648 1 Y 1 F SER 409 ? F SER 320 
1649 1 Y 1 F ASN 410 ? F ASN 321 
1650 1 Y 1 F VAL 411 ? F VAL 322 
1651 1 Y 1 F SER 412 ? F SER 323 
1652 1 Y 1 F SER 413 ? F SER 324 
1653 1 Y 1 F THR 414 ? F THR 325 
1654 1 Y 1 F GLY 415 ? F GLY 326 
1655 1 Y 1 F SER 416 ? F SER 327 
1656 1 Y 1 F ILE 417 ? F ILE 328 
1657 1 Y 1 F ASP 418 ? F ASP 329 
1658 1 Y 1 F MET 419 ? F MET 330 
1659 1 Y 1 F VAL 420 ? F VAL 331 
1660 1 Y 1 F ASP 421 ? F ASP 332 
1661 1 Y 1 F SER 422 ? F SER 333 
1662 1 Y 1 F PRO 423 ? F PRO 334 
1663 1 Y 1 F GLN 424 ? F GLN 335 
1664 1 Y 1 F LEU 425 ? F LEU 336 
1665 1 Y 1 F ALA 426 ? F ALA 337 
1666 1 Y 1 F THR 427 ? F THR 338 
1667 1 Y 1 F LEU 428 ? F LEU 339 
1668 1 Y 1 F ALA 429 ? F ALA 340 
1669 1 Y 1 F ASP 430 ? F ASP 341 
1670 1 Y 1 F GLU 431 ? F GLU 342 
1671 1 Y 1 F VAL 432 ? F VAL 343 
1672 1 Y 1 F SER 433 ? F SER 344 
1673 1 Y 1 F ALA 434 ? F ALA 345 
1674 1 Y 1 F SER 435 ? F SER 346 
1675 1 Y 1 F LEU 436 ? F LEU 347 
1676 1 Y 1 F ALA 437 ? F ALA 348 
1677 1 Y 1 F LYS 438 ? F LYS 349 
1678 1 Y 1 F GLN 439 ? F GLN 350 
1679 1 Y 1 F GLY 440 ? F GLY 351 
1680 1 Y 1 F LEU 441 ? F LEU 352 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TYR N    N N N 318 
TYR CA   C N S 319 
TYR C    C N N 320 
TYR O    O N N 321 
TYR CB   C N N 322 
TYR CG   C Y N 323 
TYR CD1  C Y N 324 
TYR CD2  C Y N 325 
TYR CE1  C Y N 326 
TYR CE2  C Y N 327 
TYR CZ   C Y N 328 
TYR OH   O N N 329 
TYR OXT  O N N 330 
TYR H    H N N 331 
TYR H2   H N N 332 
TYR HA   H N N 333 
TYR HB2  H N N 334 
TYR HB3  H N N 335 
TYR HD1  H N N 336 
TYR HD2  H N N 337 
TYR HE1  H N N 338 
TYR HE2  H N N 339 
TYR HH   H N N 340 
TYR HXT  H N N 341 
VAL N    N N N 342 
VAL CA   C N S 343 
VAL C    C N N 344 
VAL O    O N N 345 
VAL CB   C N N 346 
VAL CG1  C N N 347 
VAL CG2  C N N 348 
VAL OXT  O N N 349 
VAL H    H N N 350 
VAL H2   H N N 351 
VAL HA   H N N 352 
VAL HB   H N N 353 
VAL HG11 H N N 354 
VAL HG12 H N N 355 
VAL HG13 H N N 356 
VAL HG21 H N N 357 
VAL HG22 H N N 358 
VAL HG23 H N N 359 
VAL HXT  H N N 360 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TYR N   CA   sing N N 304 
TYR N   H    sing N N 305 
TYR N   H2   sing N N 306 
TYR CA  C    sing N N 307 
TYR CA  CB   sing N N 308 
TYR CA  HA   sing N N 309 
TYR C   O    doub N N 310 
TYR C   OXT  sing N N 311 
TYR CB  CG   sing N N 312 
TYR CB  HB2  sing N N 313 
TYR CB  HB3  sing N N 314 
TYR CG  CD1  doub Y N 315 
TYR CG  CD2  sing Y N 316 
TYR CD1 CE1  sing Y N 317 
TYR CD1 HD1  sing N N 318 
TYR CD2 CE2  doub Y N 319 
TYR CD2 HD2  sing N N 320 
TYR CE1 CZ   doub Y N 321 
TYR CE1 HE1  sing N N 322 
TYR CE2 CZ   sing Y N 323 
TYR CE2 HE2  sing N N 324 
TYR CZ  OH   sing N N 325 
TYR OH  HH   sing N N 326 
TYR OXT HXT  sing N N 327 
VAL N   CA   sing N N 328 
VAL N   H    sing N N 329 
VAL N   H2   sing N N 330 
VAL CA  C    sing N N 331 
VAL CA  CB   sing N N 332 
VAL CA  HA   sing N N 333 
VAL C   O    doub N N 334 
VAL C   OXT  sing N N 335 
VAL CB  CG1  sing N N 336 
VAL CB  CG2  sing N N 337 
VAL CB  HB   sing N N 338 
VAL CG1 HG11 sing N N 339 
VAL CG1 HG12 sing N N 340 
VAL CG1 HG13 sing N N 341 
VAL CG2 HG21 sing N N 342 
VAL CG2 HG22 sing N N 343 
VAL CG2 HG23 sing N N 344 
VAL OXT HXT  sing N N 345 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-10-22 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9H5J 
_em_admin.last_update        2024-12-04 
_em_admin.map_release_date   2024-12-04 
_em_admin.title              'PAD12 0N3R tau PHF seeded by AD' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_helical_entity.id                             1 
_em_helical_entity.image_processing_id            1 
_em_helical_entity.details                        ? 
_em_helical_entity.axial_symmetry                 C1 
_em_helical_entity.angular_rotation_per_subunit   179.393 
_em_helical_entity.axial_rise_per_subunit         2.42 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         30 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ?      ? 
MASKING                    ? 3  ? ? ? ?      ? 
'CTF CORRECTION'           ? 4  1 ? ? ?      ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ?      ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?      ? 
'MODEL FITTING'            ? 7  ? ? ? ?      ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ?      ? 
OTHER                      ? 9  ? ? ? ?      ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ? 
CLASSIFICATION             ? 12 1 ? ? ?      ? 
RECONSTRUCTION             ? 13 1 ? ? RELION 5 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Medical Research Council (MRC, United Kingdom)' 
_pdbx_audit_support.country                'United Kingdom' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9H5J 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . GLN A 1 218 ? 78.065  136.148 139.855 1.00 79.40 ? 307 GLN A N   1 
ATOM 2    C CA  . GLN A 1 218 ? 78.203  137.525 139.388 1.00 79.40 ? 307 GLN A CA  1 
ATOM 3    C C   . GLN A 1 218 ? 79.526  138.146 139.867 1.00 79.40 ? 307 GLN A C   1 
ATOM 4    O O   . GLN A 1 218 ? 79.650  138.541 141.026 1.00 79.40 ? 307 GLN A O   1 
ATOM 5    C CB  . GLN A 1 218 ? 76.977  138.331 139.857 1.00 79.40 ? 307 GLN A CB  1 
ATOM 6    C CG  . GLN A 1 218 ? 77.013  139.796 139.393 1.00 79.40 ? 307 GLN A CG  1 
ATOM 7    C CD  . GLN A 1 218 ? 75.802  140.612 139.842 1.00 79.40 ? 307 GLN A CD  1 
ATOM 8    O OE1 . GLN A 1 218 ? 75.029  140.239 140.714 1.00 79.40 ? 307 GLN A OE1 1 
ATOM 9    N NE2 . GLN A 1 218 ? 75.603  141.773 139.265 1.00 79.40 ? 307 GLN A NE2 1 
ATOM 10   N N   . ILE A 1 219 ? 80.515  138.254 138.978 1.00 76.56 ? 308 ILE A N   1 
ATOM 11   C CA  . ILE A 1 219 ? 81.786  138.943 139.244 1.00 76.56 ? 308 ILE A CA  1 
ATOM 12   C C   . ILE A 1 219 ? 81.842  140.211 138.382 1.00 76.56 ? 308 ILE A C   1 
ATOM 13   O O   . ILE A 1 219 ? 81.755  140.134 137.157 1.00 76.56 ? 308 ILE A O   1 
ATOM 14   C CB  . ILE A 1 219 ? 83.006  138.017 138.989 1.00 76.56 ? 308 ILE A CB  1 
ATOM 15   C CG1 . ILE A 1 219 ? 83.206  136.921 140.058 1.00 76.56 ? 308 ILE A CG1 1 
ATOM 16   C CG2 . ILE A 1 219 ? 84.324  138.812 138.966 1.00 76.56 ? 308 ILE A CG2 1 
ATOM 17   C CD1 . ILE A 1 219 ? 82.125  135.844 140.130 1.00 76.56 ? 308 ILE A CD1 1 
ATOM 18   N N   . VAL A 1 220 ? 82.044  141.370 139.007 1.00 72.40 ? 309 VAL A N   1 
ATOM 19   C CA  . VAL A 1 220 ? 82.369  142.634 138.330 1.00 72.40 ? 309 VAL A CA  1 
ATOM 20   C C   . VAL A 1 220 ? 83.818  142.999 138.653 1.00 72.40 ? 309 VAL A C   1 
ATOM 21   O O   . VAL A 1 220 ? 84.116  143.504 139.733 1.00 72.40 ? 309 VAL A O   1 
ATOM 22   C CB  . VAL A 1 220 ? 81.382  143.752 138.711 1.00 72.40 ? 309 VAL A CB  1 
ATOM 23   C CG1 . VAL A 1 220 ? 81.716  145.062 137.988 1.00 72.40 ? 309 VAL A CG1 1 
ATOM 24   C CG2 . VAL A 1 220 ? 79.951  143.365 138.343 1.00 72.40 ? 309 VAL A CG2 1 
ATOM 25   N N   . TYR A 1 221 ? 84.730  142.698 137.731 1.00 69.33 ? 310 TYR A N   1 
ATOM 26   C CA  . TYR A 1 221 ? 86.165  142.953 137.865 1.00 69.33 ? 310 TYR A CA  1 
ATOM 27   C C   . TYR A 1 221 ? 86.533  144.223 137.095 1.00 69.33 ? 310 TYR A C   1 
ATOM 28   O O   . TYR A 1 221 ? 86.713  144.181 135.878 1.00 69.33 ? 310 TYR A O   1 
ATOM 29   C CB  . TYR A 1 221 ? 86.924  141.712 137.379 1.00 69.33 ? 310 TYR A CB  1 
ATOM 30   C CG  . TYR A 1 221 ? 88.405  141.689 137.705 1.00 69.33 ? 310 TYR A CG  1 
ATOM 31   C CD1 . TYR A 1 221 ? 89.353  142.273 136.844 1.00 69.33 ? 310 TYR A CD1 1 
ATOM 32   C CD2 . TYR A 1 221 ? 88.838  141.011 138.856 1.00 69.33 ? 310 TYR A CD2 1 
ATOM 33   C CE1 . TYR A 1 221 ? 90.728  142.134 137.108 1.00 69.33 ? 310 TYR A CE1 1 
ATOM 34   C CE2 . TYR A 1 221 ? 90.210  140.857 139.116 1.00 69.33 ? 310 TYR A CE2 1 
ATOM 35   C CZ  . TYR A 1 221 ? 91.158  141.391 138.225 1.00 69.33 ? 310 TYR A CZ  1 
ATOM 36   O OH  . TYR A 1 221 ? 92.476  141.142 138.427 1.00 69.33 ? 310 TYR A OH  1 
ATOM 37   N N   . LYS A 1 222 ? 86.591  145.370 137.776 1.00 65.39 ? 311 LYS A N   1 
ATOM 38   C CA  . LYS A 1 222 ? 86.727  146.685 137.132 1.00 65.39 ? 311 LYS A CA  1 
ATOM 39   C C   . LYS A 1 222 ? 87.739  147.600 137.842 1.00 65.39 ? 311 LYS A C   1 
ATOM 40   O O   . LYS A 1 222 ? 87.382  148.694 138.270 1.00 65.39 ? 311 LYS A O   1 
ATOM 41   C CB  . LYS A 1 222 ? 85.318  147.283 136.950 1.00 65.39 ? 311 LYS A CB  1 
ATOM 42   C CG  . LYS A 1 222 ? 85.306  148.423 135.924 1.00 65.39 ? 311 LYS A CG  1 
ATOM 43   C CD  . LYS A 1 222 ? 83.878  148.857 135.581 1.00 65.39 ? 311 LYS A CD  1 
ATOM 44   C CE  . LYS A 1 222 ? 83.912  150.005 134.565 1.00 65.39 ? 311 LYS A CE  1 
ATOM 45   N NZ  . LYS A 1 222 ? 82.551  150.395 134.134 1.00 65.39 ? 311 LYS A NZ  1 
ATOM 46   N N   . PRO A 1 223 ? 89.007  147.186 138.011 1.00 63.67 ? 312 PRO A N   1 
ATOM 47   C CA  . PRO A 1 223 ? 90.038  148.048 138.586 1.00 63.67 ? 312 PRO A CA  1 
ATOM 48   C C   . PRO A 1 223 ? 90.243  149.305 137.728 1.00 63.67 ? 312 PRO A C   1 
ATOM 49   O O   . PRO A 1 223 ? 90.221  149.220 136.501 1.00 63.67 ? 312 PRO A O   1 
ATOM 50   C CB  . PRO A 1 223 ? 91.297  147.175 138.640 1.00 63.67 ? 312 PRO A CB  1 
ATOM 51   C CG  . PRO A 1 223 ? 91.098  146.181 137.501 1.00 63.67 ? 312 PRO A CG  1 
ATOM 52   C CD  . PRO A 1 223 ? 89.593  145.948 137.523 1.00 63.67 ? 312 PRO A CD  1 
ATOM 53   N N   . VAL A 1 224 ? 90.467  150.468 138.345 1.00 61.45 ? 313 VAL A N   1 
ATOM 54   C CA  . VAL A 1 224 ? 90.752  151.733 137.641 1.00 61.45 ? 313 VAL A CA  1 
ATOM 55   C C   . VAL A 1 224 ? 92.126  152.278 138.022 1.00 61.45 ? 313 VAL A C   1 
ATOM 56   O O   . VAL A 1 224 ? 92.396  152.550 139.189 1.00 61.45 ? 313 VAL A O   1 
ATOM 57   C CB  . VAL A 1 224 ? 89.648  152.777 137.889 1.00 61.45 ? 313 VAL A CB  1 
ATOM 58   C CG1 . VAL A 1 224 ? 89.973  154.148 137.283 1.00 61.45 ? 313 VAL A CG1 1 
ATOM 59   C CG2 . VAL A 1 224 ? 88.316  152.310 137.296 1.00 61.45 ? 313 VAL A CG2 1 
ATOM 60   N N   . ASP A 1 225 ? 92.989  152.484 137.033 1.00 58.83 ? 314 ASP A N   1 
ATOM 61   C CA  . ASP A 1 225 ? 94.297  153.118 137.193 1.00 58.83 ? 314 ASP A CA  1 
ATOM 62   C C   . ASP A 1 225 ? 94.355  154.446 136.426 1.00 58.83 ? 314 ASP A C   1 
ATOM 63   O O   . ASP A 1 225 ? 94.113  154.491 135.222 1.00 58.83 ? 314 ASP A O   1 
ATOM 64   C CB  . ASP A 1 225 ? 95.386  152.142 136.730 1.00 58.83 ? 314 ASP A CB  1 
ATOM 65   C CG  . ASP A 1 225 ? 96.793  152.748 136.734 1.00 58.83 ? 314 ASP A CG  1 
ATOM 66   O OD1 . ASP A 1 225 ? 97.042  153.748 137.442 1.00 58.83 ? 314 ASP A OD1 1 
ATOM 67   O OD2 . ASP A 1 225 ? 97.662  152.212 136.015 1.00 58.83 ? 314 ASP A OD2 1 
ATOM 68   N N   . LEU A 1 226 ? 94.699  155.520 137.128 1.00 56.80 ? 315 LEU A N   1 
ATOM 69   C CA  . LEU A 1 226 ? 94.867  156.881 136.623 1.00 56.80 ? 315 LEU A CA  1 
ATOM 70   C C   . LEU A 1 226 ? 96.218  157.481 137.074 1.00 56.80 ? 315 LEU A C   1 
ATOM 71   O O   . LEU A 1 226 ? 96.449  158.683 136.950 1.00 56.80 ? 315 LEU A O   1 
ATOM 72   C CB  . LEU A 1 226 ? 93.664  157.713 137.109 1.00 56.80 ? 315 LEU A CB  1 
ATOM 73   C CG  . LEU A 1 226 ? 92.296  157.276 136.555 1.00 56.80 ? 315 LEU A CG  1 
ATOM 74   C CD1 . LEU A 1 226 ? 91.169  157.885 137.385 1.00 56.80 ? 315 LEU A CD1 1 
ATOM 75   C CD2 . LEU A 1 226 ? 92.119  157.707 135.105 1.00 56.80 ? 315 LEU A CD2 1 
ATOM 76   N N   . SER A 1 227 ? 97.108  156.662 137.637 1.00 55.49 ? 316 SER A N   1 
ATOM 77   C CA  . SER A 1 227 ? 98.378  157.065 138.259 1.00 55.49 ? 316 SER A CA  1 
ATOM 78   C C   . SER A 1 227 ? 99.457  157.530 137.263 1.00 55.49 ? 316 SER A C   1 
ATOM 79   O O   . SER A 1 227 ? 99.326  157.312 136.063 1.00 55.49 ? 316 SER A O   1 
ATOM 80   C CB  . SER A 1 227 ? 98.884  155.880 139.080 1.00 55.49 ? 316 SER A CB  1 
ATOM 81   O OG  . SER A 1 227 ? 99.228  154.816 138.226 1.00 55.49 ? 316 SER A OG  1 
ATOM 82   N N   . LYS A 1 228 ? 100.536 158.165 137.743 1.00 53.46 ? 317 LYS A N   1 
ATOM 83   C CA  . LYS A 1 228 ? 101.652 158.687 136.914 1.00 53.46 ? 317 LYS A CA  1 
ATOM 84   C C   . LYS A 1 228 ? 103.039 158.362 137.493 1.00 53.46 ? 317 LYS A C   1 
ATOM 85   O O   . LYS A 1 228 ? 103.212 158.352 138.710 1.00 53.46 ? 317 LYS A O   1 
ATOM 86   C CB  . LYS A 1 228 ? 101.520 160.212 136.726 1.00 53.46 ? 317 LYS A CB  1 
ATOM 87   C CG  . LYS A 1 228 ? 100.253 160.706 136.004 1.00 53.46 ? 317 LYS A CG  1 
ATOM 88   C CD  . LYS A 1 228 ? 100.235 160.330 134.514 1.00 53.46 ? 317 LYS A CD  1 
ATOM 89   C CE  . LYS A 1 228 ? 99.082  160.971 133.727 1.00 53.46 ? 317 LYS A CE  1 
ATOM 90   N NZ  . LYS A 1 228 ? 97.772  160.317 133.968 1.00 53.46 ? 317 LYS A NZ  1 
ATOM 91   N N   . VAL A 1 229 ? 104.028 158.153 136.625 1.00 52.45 ? 318 VAL A N   1 
ATOM 92   C CA  . VAL A 1 229 ? 105.460 158.046 136.969 1.00 52.45 ? 318 VAL A CA  1 
ATOM 93   C C   . VAL A 1 229 ? 106.257 159.011 136.089 1.00 52.45 ? 318 VAL A C   1 
ATOM 94   O O   . VAL A 1 229 ? 106.146 158.944 134.868 1.00 52.45 ? 318 VAL A O   1 
ATOM 95   C CB  . VAL A 1 229 ? 105.986 156.603 136.829 1.00 52.45 ? 318 VAL A CB  1 
ATOM 96   C CG1 . VAL A 1 229 ? 107.420 156.479 137.354 1.00 52.45 ? 318 VAL A CG1 1 
ATOM 97   C CG2 . VAL A 1 229 ? 105.132 155.588 137.592 1.00 52.45 ? 318 VAL A CG2 1 
ATOM 98   N N   . THR A 1 230 ? 107.052 159.913 136.668 1.00 52.09 ? 319 THR A N   1 
ATOM 99   C CA  . THR A 1 230 ? 107.575 161.102 135.961 1.00 52.09 ? 319 THR A CA  1 
ATOM 100  C C   . THR A 1 230 ? 108.981 161.492 136.423 1.00 52.09 ? 319 THR A C   1 
ATOM 101  O O   . THR A 1 230 ? 109.350 161.255 137.571 1.00 52.09 ? 319 THR A O   1 
ATOM 102  C CB  . THR A 1 230 ? 106.591 162.276 136.173 1.00 52.09 ? 319 THR A CB  1 
ATOM 103  O OG1 . THR A 1 230 ? 105.347 162.003 135.584 1.00 52.09 ? 319 THR A OG1 1 
ATOM 104  C CG2 . THR A 1 230 ? 107.037 163.624 135.614 1.00 52.09 ? 319 THR A CG2 1 
ATOM 105  N N   . SER A 1 231 ? 109.795 162.123 135.573 1.00 49.98 ? 320 SER A N   1 
ATOM 106  C CA  . SER A 1 231 ? 111.066 162.748 135.989 1.00 49.98 ? 320 SER A CA  1 
ATOM 107  C C   . SER A 1 231 ? 111.474 163.957 135.155 1.00 49.98 ? 320 SER A C   1 
ATOM 108  O O   . SER A 1 231 ? 111.167 164.030 133.968 1.00 49.98 ? 320 SER A O   1 
ATOM 109  C CB  . SER A 1 231 ? 112.218 161.742 135.942 1.00 49.98 ? 320 SER A CB  1 
ATOM 110  O OG  . SER A 1 231 ? 111.897 160.636 136.750 1.00 49.98 ? 320 SER A OG  1 
ATOM 111  N N   . LYS A 1 232 ? 112.256 164.847 135.768 1.00 47.86 ? 321 LYS A N   1 
ATOM 112  C CA  . LYS A 1 232 ? 113.086 165.855 135.100 1.00 47.86 ? 321 LYS A CA  1 
ATOM 113  C C   . LYS A 1 232 ? 114.529 165.758 135.583 1.00 47.86 ? 321 LYS A C   1 
ATOM 114  O O   . LYS A 1 232 ? 114.777 165.652 136.781 1.00 47.86 ? 321 LYS A O   1 
ATOM 115  C CB  . LYS A 1 232 ? 112.535 167.267 135.342 1.00 47.86 ? 321 LYS A CB  1 
ATOM 116  C CG  . LYS A 1 232 ? 111.202 167.504 134.630 1.00 47.86 ? 321 LYS A CG  1 
ATOM 117  C CD  . LYS A 1 232 ? 110.814 168.985 134.687 1.00 47.86 ? 321 LYS A CD  1 
ATOM 118  C CE  . LYS A 1 232 ? 109.563 169.232 133.841 1.00 47.86 ? 321 LYS A CE  1 
ATOM 119  N NZ  . LYS A 1 232 ? 109.299 170.672 133.664 1.00 47.86 ? 321 LYS A NZ  1 
ATOM 120  N N   . CYS A 1 233 ? 115.474 165.838 134.657 1.00 47.04 ? 322 CYS A N   1 
ATOM 121  C CA  . CYS A 1 233 ? 116.903 165.922 134.928 1.00 47.04 ? 322 CYS A CA  1 
ATOM 122  C C   . CYS A 1 233 ? 117.489 167.073 134.097 1.00 47.04 ? 322 CYS A C   1 
ATOM 123  O O   . CYS A 1 233 ? 117.291 167.121 132.884 1.00 47.04 ? 322 CYS A O   1 
ATOM 124  C CB  . CYS A 1 233 ? 117.531 164.558 134.628 1.00 47.04 ? 322 CYS A CB  1 
ATOM 125  S SG  . CYS A 1 233 ? 119.307 164.562 134.980 1.00 47.04 ? 322 CYS A SG  1 
ATOM 126  N N   . GLY A 1 234 ? 118.184 168.020 134.725 1.00 45.03 ? 323 GLY A N   1 
ATOM 127  C CA  . GLY A 1 234 ? 118.611 169.253 134.057 1.00 45.03 ? 323 GLY A CA  1 
ATOM 128  C C   . GLY A 1 234 ? 119.750 169.080 133.047 1.00 45.03 ? 323 GLY A C   1 
ATOM 129  O O   . GLY A 1 234 ? 119.795 169.771 132.029 1.00 45.03 ? 323 GLY A O   1 
ATOM 130  N N   . SER A 1 235 ? 120.665 168.154 133.313 1.00 43.18 ? 324 SER A N   1 
ATOM 131  C CA  . SER A 1 235 ? 121.789 167.776 132.455 1.00 43.18 ? 324 SER A CA  1 
ATOM 132  C C   . SER A 1 235 ? 122.392 166.471 132.965 1.00 43.18 ? 324 SER A C   1 
ATOM 133  O O   . SER A 1 235 ? 122.547 166.306 134.171 1.00 43.18 ? 324 SER A O   1 
ATOM 134  C CB  . SER A 1 235 ? 122.862 168.862 132.458 1.00 43.18 ? 324 SER A CB  1 
ATOM 135  O OG  . SER A 1 235 ? 123.943 168.482 131.636 1.00 43.18 ? 324 SER A OG  1 
ATOM 136  N N   . LEU A 1 236 ? 122.701 165.537 132.069 1.00 41.17 ? 325 LEU A N   1 
ATOM 137  C CA  . LEU A 1 236 ? 123.194 164.198 132.391 1.00 41.17 ? 325 LEU A CA  1 
ATOM 138  C C   . LEU A 1 236 ? 124.472 163.890 131.593 1.00 41.17 ? 325 LEU A C   1 
ATOM 139  O O   . LEU A 1 236 ? 124.422 163.847 130.366 1.00 41.17 ? 325 LEU A O   1 
ATOM 140  C CB  . LEU A 1 236 ? 122.035 163.211 132.145 1.00 41.17 ? 325 LEU A CB  1 
ATOM 141  C CG  . LEU A 1 236 ? 122.354 161.724 132.352 1.00 41.17 ? 325 LEU A CG  1 
ATOM 142  C CD1 . LEU A 1 236 ? 122.964 161.443 133.716 1.00 41.17 ? 325 LEU A CD1 1 
ATOM 143  C CD2 . LEU A 1 236 ? 121.065 160.911 132.244 1.00 41.17 ? 325 LEU A CD2 1 
ATOM 144  N N   . GLY A 1 237 ? 125.619 163.685 132.243 1.00 37.60 ? 326 GLY A N   1 
ATOM 145  C CA  . GLY A 1 237 ? 126.892 163.465 131.540 1.00 37.60 ? 326 GLY A CA  1 
ATOM 146  C C   . GLY A 1 237 ? 128.141 163.426 132.421 1.00 37.60 ? 326 GLY A C   1 
ATOM 147  O O   . GLY A 1 237 ? 128.041 163.399 133.639 1.00 37.60 ? 326 GLY A O   1 
ATOM 148  N N   . ASN A 1 238 ? 129.332 163.419 131.813 1.00 34.69 ? 327 ASN A N   1 
ATOM 149  C CA  . ASN A 1 238 ? 130.640 163.302 132.484 1.00 34.69 ? 327 ASN A CA  1 
ATOM 150  C C   . ASN A 1 238 ? 130.750 162.030 133.349 1.00 34.69 ? 327 ASN A C   1 
ATOM 151  O O   . ASN A 1 238 ? 131.005 162.079 134.548 1.00 34.69 ? 327 ASN A O   1 
ATOM 152  C CB  . ASN A 1 238 ? 130.966 164.628 133.196 1.00 34.69 ? 327 ASN A CB  1 
ATOM 153  C CG  . ASN A 1 238 ? 132.398 164.749 133.681 1.00 34.69 ? 327 ASN A CG  1 
ATOM 154  O OD1 . ASN A 1 238 ? 133.307 164.065 133.245 1.00 34.69 ? 327 ASN A OD1 1 
ATOM 155  N ND2 . ASN A 1 238 ? 132.653 165.657 134.582 1.00 34.69 ? 327 ASN A ND2 1 
ATOM 156  N N   . ILE A 1 239 ? 130.474 160.878 132.737 1.00 33.92 ? 328 ILE A N   1 
ATOM 157  C CA  . ILE A 1 239 ? 130.496 159.546 133.355 1.00 33.92 ? 328 ILE A CA  1 
ATOM 158  C C   . ILE A 1 239 ? 131.627 158.720 132.720 1.00 33.92 ? 328 ILE A C   1 
ATOM 159  O O   . ILE A 1 239 ? 131.679 158.581 131.503 1.00 33.92 ? 328 ILE A O   1 
ATOM 160  C CB  . ILE A 1 239 ? 129.109 158.875 133.223 1.00 33.92 ? 328 ILE A CB  1 
ATOM 161  C CG1 . ILE A 1 239 ? 128.018 159.671 133.971 1.00 33.92 ? 328 ILE A CG1 1 
ATOM 162  C CG2 . ILE A 1 239 ? 129.121 157.430 133.743 1.00 33.92 ? 328 ILE A CG2 1 
ATOM 163  C CD1 . ILE A 1 239 ? 126.629 159.503 133.362 1.00 33.92 ? 328 ILE A CD1 1 
ATOM 164  N N   . HIS A 1 240 ? 132.537 158.170 133.521 1.00 32.69 ? 329 HIS A N   1 
ATOM 165  C CA  . HIS A 1 240 ? 133.703 157.395 133.067 1.00 32.69 ? 329 HIS A CA  1 
ATOM 166  C C   . HIS A 1 240 ? 133.689 155.988 133.666 1.00 32.69 ? 329 HIS A C   1 
ATOM 167  O O   . HIS A 1 240 ? 133.757 155.850 134.881 1.00 32.69 ? 329 HIS A O   1 
ATOM 168  C CB  . HIS A 1 240 ? 134.996 158.131 133.464 1.00 32.69 ? 329 HIS A CB  1 
ATOM 169  C CG  . HIS A 1 240 ? 135.109 159.545 132.945 1.00 32.69 ? 329 HIS A CG  1 
ATOM 170  N ND1 . HIS A 1 240 ? 135.676 159.923 131.729 1.00 32.69 ? 329 HIS A ND1 1 
ATOM 171  C CD2 . HIS A 1 240 ? 134.590 160.650 133.547 1.00 32.69 ? 329 HIS A CD2 1 
ATOM 172  C CE1 . HIS A 1 240 ? 135.482 161.248 131.629 1.00 32.69 ? 329 HIS A CE1 1 
ATOM 173  N NE2 . HIS A 1 240 ? 134.834 161.707 132.707 1.00 32.69 ? 329 HIS A NE2 1 
ATOM 174  N N   . HIS A 1 241 ? 133.639 154.938 132.848 1.00 32.07 ? 330 HIS A N   1 
ATOM 175  C CA  . HIS A 1 241 ? 133.713 153.542 133.296 1.00 32.07 ? 330 HIS A CA  1 
ATOM 176  C C   . HIS A 1 241 ? 134.945 152.862 132.685 1.00 32.07 ? 330 HIS A C   1 
ATOM 177  O O   . HIS A 1 241 ? 135.034 152.716 131.468 1.00 32.07 ? 330 HIS A O   1 
ATOM 178  C CB  . HIS A 1 241 ? 132.399 152.836 132.936 1.00 32.07 ? 330 HIS A CB  1 
ATOM 179  C CG  . HIS A 1 241 ? 132.258 151.396 133.378 1.00 32.07 ? 330 HIS A CG  1 
ATOM 180  N ND1 . HIS A 1 241 ? 131.325 150.511 132.902 1.00 32.07 ? 330 HIS A ND1 1 
ATOM 181  C CD2 . HIS A 1 241 ? 132.865 150.774 134.433 1.00 32.07 ? 330 HIS A CD2 1 
ATOM 182  C CE1 . HIS A 1 241 ? 131.383 149.384 133.620 1.00 32.07 ? 330 HIS A CE1 1 
ATOM 183  N NE2 . HIS A 1 241 ? 132.298 149.507 134.585 1.00 32.07 ? 330 HIS A NE2 1 
ATOM 184  N N   . LYS A 1 242 ? 135.905 152.460 133.521 1.00 31.44 ? 331 LYS A N   1 
ATOM 185  C CA  . LYS A 1 242 ? 137.267 152.074 133.108 1.00 31.44 ? 331 LYS A CA  1 
ATOM 186  C C   . LYS A 1 242 ? 137.774 150.822 133.848 1.00 31.44 ? 331 LYS A C   1 
ATOM 187  O O   . LYS A 1 242 ? 138.521 150.951 134.813 1.00 31.44 ? 331 LYS A O   1 
ATOM 188  C CB  . LYS A 1 242 ? 138.173 153.305 133.314 1.00 31.44 ? 331 LYS A CB  1 
ATOM 189  C CG  . LYS A 1 242 ? 138.042 154.328 132.180 1.00 31.44 ? 331 LYS A CG  1 
ATOM 190  C CD  . LYS A 1 242 ? 138.731 155.664 132.469 1.00 31.44 ? 331 LYS A CD  1 
ATOM 191  C CE  . LYS A 1 242 ? 140.253 155.556 132.571 1.00 31.44 ? 331 LYS A CE  1 
ATOM 192  N NZ  . LYS A 1 242 ? 140.859 156.902 132.685 1.00 31.44 ? 331 LYS A NZ  1 
ATOM 193  N N   . PRO A 1 243 ? 137.352 149.601 133.464 1.00 31.12 ? 332 PRO A N   1 
ATOM 194  C CA  . PRO A 1 243 ? 137.773 148.348 134.103 1.00 31.12 ? 332 PRO A CA  1 
ATOM 195  C C   . PRO A 1 243 ? 139.176 147.866 133.718 1.00 31.12 ? 332 PRO A C   1 
ATOM 196  O O   . PRO A 1 243 ? 139.582 147.942 132.562 1.00 31.12 ? 332 PRO A O   1 
ATOM 197  C CB  . PRO A 1 243 ? 136.711 147.307 133.736 1.00 31.12 ? 332 PRO A CB  1 
ATOM 198  C CG  . PRO A 1 243 ? 135.546 148.136 133.221 1.00 31.12 ? 332 PRO A CG  1 
ATOM 199  C CD  . PRO A 1 243 ? 136.244 149.315 132.575 1.00 31.12 ? 332 PRO A CD  1 
ATOM 200  N N   . GLY A 1 244 ? 139.905 147.310 134.684 1.00 30.86 ? 333 GLY A N   1 
ATOM 201  C CA  . GLY A 1 244 ? 141.288 146.842 134.555 1.00 30.86 ? 333 GLY A CA  1 
ATOM 202  C C   . GLY A 1 244 ? 141.462 145.338 134.365 1.00 30.86 ? 333 GLY A C   1 
ATOM 203  O O   . GLY A 1 244 ? 142.252 144.725 135.076 1.00 30.86 ? 333 GLY A O   1 
ATOM 204  N N   . GLY A 1 245 ? 140.748 144.724 133.427 1.00 30.37 ? 334 GLY A N   1 
ATOM 205  C CA  . GLY A 1 245 ? 140.915 143.309 133.080 1.00 30.37 ? 334 GLY A CA  1 
ATOM 206  C C   . GLY A 1 245 ? 140.381 142.334 134.128 1.00 30.37 ? 334 GLY A C   1 
ATOM 207  O O   . GLY A 1 245 ? 139.321 142.555 134.704 1.00 30.37 ? 334 GLY A O   1 
ATOM 208  N N   . GLY A 1 246 ? 141.094 141.237 134.364 1.00 30.75 ? 335 GLY A N   1 
ATOM 209  C CA  . GLY A 1 246 ? 140.700 140.164 135.285 1.00 30.75 ? 335 GLY A CA  1 
ATOM 210  C C   . GLY A 1 246 ? 140.811 138.773 134.665 1.00 30.75 ? 335 GLY A C   1 
ATOM 211  O O   . GLY A 1 246 ? 141.149 138.637 133.494 1.00 30.75 ? 335 GLY A O   1 
ATOM 212  N N   . GLN A 1 247 ? 140.549 137.720 135.437 1.00 31.95 ? 336 GLN A N   1 
ATOM 213  C CA  . GLN A 1 247 ? 140.627 136.340 134.946 1.00 31.95 ? 336 GLN A CA  1 
ATOM 214  C C   . GLN A 1 247 ? 139.559 135.419 135.548 1.00 31.95 ? 336 GLN A C   1 
ATOM 215  O O   . GLN A 1 247 ? 139.304 135.470 136.747 1.00 31.95 ? 336 GLN A O   1 
ATOM 216  C CB  . GLN A 1 247 ? 142.051 135.839 135.203 1.00 31.95 ? 336 GLN A CB  1 
ATOM 217  C CG  . GLN A 1 247 ? 142.394 134.565 134.429 1.00 31.95 ? 336 GLN A CG  1 
ATOM 218  C CD  . GLN A 1 247 ? 143.888 134.494 134.169 1.00 31.95 ? 336 GLN A CD  1 
ATOM 219  O OE1 . GLN A 1 247 ? 144.686 134.642 135.071 1.00 31.95 ? 336 GLN A OE1 1 
ATOM 220  N NE2 . GLN A 1 247 ? 144.331 134.297 132.954 1.00 31.95 ? 336 GLN A NE2 1 
ATOM 221  N N   . VAL A 1 248 ? 138.950 134.553 134.739 1.00 34.06 ? 337 VAL A N   1 
ATOM 222  C CA  . VAL A 1 248 ? 137.895 133.617 135.165 1.00 34.06 ? 337 VAL A CA  1 
ATOM 223  C C   . VAL A 1 248 ? 138.152 132.221 134.603 1.00 34.06 ? 337 VAL A C   1 
ATOM 224  O O   . VAL A 1 248 ? 138.430 132.084 133.417 1.00 34.06 ? 337 VAL A O   1 
ATOM 225  C CB  . VAL A 1 248 ? 136.491 134.113 134.752 1.00 34.06 ? 337 VAL A CB  1 
ATOM 226  C CG1 . VAL A 1 248 ? 135.380 133.205 135.282 1.00 34.06 ? 337 VAL A CG1 1 
ATOM 227  C CG2 . VAL A 1 248 ? 136.199 135.524 135.259 1.00 34.06 ? 337 VAL A CG2 1 
ATOM 228  N N   . GLU A 1 249 ? 138.021 131.178 135.416 1.00 37.66 ? 338 GLU A N   1 
ATOM 229  C CA  . GLU A 1 249 ? 138.119 129.775 134.999 1.00 37.66 ? 338 GLU A CA  1 
ATOM 230  C C   . GLU A 1 249 ? 137.000 128.926 135.611 1.00 37.66 ? 338 GLU A C   1 
ATOM 231  O O   . GLU A 1 249 ? 136.731 129.019 136.807 1.00 37.66 ? 338 GLU A O   1 
ATOM 232  C CB  . GLU A 1 249 ? 139.510 129.242 135.369 1.00 37.66 ? 338 GLU A CB  1 
ATOM 233  C CG  . GLU A 1 249 ? 139.715 127.764 135.013 1.00 37.66 ? 338 GLU A CG  1 
ATOM 234  C CD  . GLU A 1 249 ? 141.139 127.264 135.302 1.00 37.66 ? 338 GLU A CD  1 
ATOM 235  O OE1 . GLU A 1 249 ? 142.088 128.077 135.386 1.00 37.66 ? 338 GLU A OE1 1 
ATOM 236  O OE2 . GLU A 1 249 ? 141.325 126.034 135.416 1.00 37.66 ? 338 GLU A OE2 1 
ATOM 237  N N   . VAL A 1 250 ? 136.359 128.068 134.817 1.00 39.59 ? 339 VAL A N   1 
ATOM 238  C CA  . VAL A 1 250 ? 135.299 127.153 135.276 1.00 39.59 ? 339 VAL A CA  1 
ATOM 239  C C   . VAL A 1 250 ? 135.520 125.746 134.714 1.00 39.59 ? 339 VAL A C   1 
ATOM 240  O O   . VAL A 1 250 ? 135.826 125.605 133.534 1.00 39.59 ? 339 VAL A O   1 
ATOM 241  C CB  . VAL A 1 250 ? 133.890 127.683 134.931 1.00 39.59 ? 339 VAL A CB  1 
ATOM 242  C CG1 . VAL A 1 250 ? 132.812 126.785 135.535 1.00 39.59 ? 339 VAL A CG1 1 
ATOM 243  C CG2 . VAL A 1 250 ? 133.640 129.111 135.431 1.00 39.59 ? 339 VAL A CG2 1 
ATOM 244  N N   . LYS A 1 251 ? 135.333 124.697 135.519 1.00 44.07 ? 340 LYS A N   1 
ATOM 245  C CA  . LYS A 1 251 ? 135.443 123.288 135.100 1.00 44.07 ? 340 LYS A CA  1 
ATOM 246  C C   . LYS A 1 251 ? 134.225 122.466 135.533 1.00 44.07 ? 340 LYS A C   1 
ATOM 247  O O   . LYS A 1 251 ? 133.810 122.558 136.683 1.00 44.07 ? 340 LYS A O   1 
ATOM 248  C CB  . LYS A 1 251 ? 136.764 122.727 135.646 1.00 44.07 ? 340 LYS A CB  1 
ATOM 249  C CG  . LYS A 1 251 ? 137.051 121.306 135.143 1.00 44.07 ? 340 LYS A CG  1 
ATOM 250  C CD  . LYS A 1 251 ? 138.419 120.765 135.571 1.00 44.07 ? 340 LYS A CD  1 
ATOM 251  C CE  . LYS A 1 251 ? 139.578 121.509 134.904 1.00 44.07 ? 340 LYS A CE  1 
ATOM 252  N NZ  . LYS A 1 251 ? 140.884 120.886 135.187 1.00 44.07 ? 340 LYS A NZ  1 
ATOM 253  N N   . SER A 1 252 ? 133.687 121.642 134.632 1.00 48.72 ? 341 SER A N   1 
ATOM 254  C CA  . SER A 1 252 ? 132.567 120.703 134.852 1.00 48.72 ? 341 SER A CA  1 
ATOM 255  C C   . SER A 1 252 ? 132.752 119.413 134.043 1.00 48.72 ? 341 SER A C   1 
ATOM 256  O O   . SER A 1 252 ? 133.317 119.459 132.953 1.00 48.72 ? 341 SER A O   1 
ATOM 257  C CB  . SER A 1 252 ? 131.226 121.319 134.437 1.00 48.72 ? 341 SER A CB  1 
ATOM 258  O OG  . SER A 1 252 ? 130.925 122.488 135.165 1.00 48.72 ? 341 SER A OG  1 
ATOM 259  N N   . GLU A 1 253 ? 132.233 118.270 134.500 1.00 51.37 ? 342 GLU A N   1 
ATOM 260  C CA  . GLU A 1 253 ? 132.156 117.055 133.670 1.00 51.37 ? 342 GLU A CA  1 
ATOM 261  C C   . GLU A 1 253 ? 130.849 116.997 132.869 1.00 51.37 ? 342 GLU A C   1 
ATOM 262  O O   . GLU A 1 253 ? 130.890 116.692 131.679 1.00 51.37 ? 342 GLU A O   1 
ATOM 263  C CB  . GLU A 1 253 ? 132.319 115.769 134.499 1.00 51.37 ? 342 GLU A CB  1 
ATOM 264  C CG  . GLU A 1 253 ? 133.600 115.689 135.344 1.00 51.37 ? 342 GLU A CG  1 
ATOM 265  C CD  . GLU A 1 253 ? 134.903 115.600 134.529 1.00 51.37 ? 342 GLU A CD  1 
ATOM 266  O OE1 . GLU A 1 253 ? 134.878 115.158 133.359 1.00 51.37 ? 342 GLU A OE1 1 
ATOM 267  O OE2 . GLU A 1 253 ? 135.983 115.943 135.062 1.00 51.37 ? 342 GLU A OE2 1 
ATOM 268  N N   . LYS A 1 254 ? 129.694 117.303 133.479 1.00 50.94 ? 343 LYS A N   1 
ATOM 269  C CA  . LYS A 1 254 ? 128.371 117.206 132.823 1.00 50.94 ? 343 LYS A CA  1 
ATOM 270  C C   . LYS A 1 254 ? 127.412 118.342 133.180 1.00 50.94 ? 343 LYS A C   1 
ATOM 271  O O   . LYS A 1 254 ? 127.388 118.816 134.312 1.00 50.94 ? 343 LYS A O   1 
ATOM 272  C CB  . LYS A 1 254 ? 127.710 115.844 133.119 1.00 50.94 ? 343 LYS A CB  1 
ATOM 273  C CG  . LYS A 1 254 ? 128.462 114.677 132.467 1.00 50.94 ? 343 LYS A CG  1 
ATOM 274  C CD  . LYS A 1 254 ? 127.642 113.386 132.514 1.00 50.94 ? 343 LYS A CD  1 
ATOM 275  C CE  . LYS A 1 254 ? 128.416 112.246 131.852 1.00 50.94 ? 343 LYS A CE  1 
ATOM 276  N NZ  . LYS A 1 254 ? 127.594 111.033 131.706 1.00 50.94 ? 343 LYS A NZ  1 
ATOM 277  N N   . LEU A 1 255 ? 126.574 118.717 132.218 1.00 50.12 ? 344 LEU A N   1 
ATOM 278  C CA  . LEU A 1 255 ? 125.490 119.693 132.344 1.00 50.12 ? 344 LEU A CA  1 
ATOM 279  C C   . LEU A 1 255 ? 124.188 119.056 131.849 1.00 50.12 ? 344 LEU A C   1 
ATOM 280  O O   . LEU A 1 255 ? 124.170 118.465 130.769 1.00 50.12 ? 344 LEU A O   1 
ATOM 281  C CB  . LEU A 1 255 ? 125.790 120.942 131.490 1.00 50.12 ? 344 LEU A CB  1 
ATOM 282  C CG  . LEU A 1 255 ? 127.177 121.588 131.645 1.00 50.12 ? 344 LEU A CG  1 
ATOM 283  C CD1 . LEU A 1 255 ? 127.362 122.678 130.597 1.00 50.12 ? 344 LEU A CD1 1 
ATOM 284  C CD2 . LEU A 1 255 ? 127.348 122.231 133.005 1.00 50.12 ? 344 LEU A CD2 1 
ATOM 285  N N   . ASP A 1 256 ? 123.085 119.199 132.577 1.00 49.93 ? 345 ASP A N   1 
ATOM 286  C CA  . ASP A 1 256 ? 121.767 118.711 132.148 1.00 49.93 ? 345 ASP A CA  1 
ATOM 287  C C   . ASP A 1 256 ? 120.659 119.680 132.582 1.00 49.93 ? 345 ASP A C   1 
ATOM 288  O O   . ASP A 1 256 ? 120.293 119.737 133.751 1.00 49.93 ? 345 ASP A O   1 
ATOM 289  C CB  . ASP A 1 256 ? 121.555 117.282 132.676 1.00 49.93 ? 345 ASP A CB  1 
ATOM 290  C CG  . ASP A 1 256 ? 120.363 116.557 132.048 1.00 49.93 ? 345 ASP A CG  1 
ATOM 291  O OD1 . ASP A 1 256 ? 119.653 117.144 131.202 1.00 49.93 ? 345 ASP A OD1 1 
ATOM 292  O OD2 . ASP A 1 256 ? 120.169 115.362 132.363 1.00 49.93 ? 345 ASP A OD2 1 
ATOM 293  N N   . PHE A 1 257 ? 120.179 120.513 131.661 1.00 48.05 ? 346 PHE A N   1 
ATOM 294  C CA  . PHE A 1 257 ? 119.202 121.569 131.930 1.00 48.05 ? 346 PHE A CA  1 
ATOM 295  C C   . PHE A 1 257 ? 117.865 121.266 131.247 1.00 48.05 ? 346 PHE A C   1 
ATOM 296  O O   . PHE A 1 257 ? 117.837 121.049 130.035 1.00 48.05 ? 346 PHE A O   1 
ATOM 297  C CB  . PHE A 1 257 ? 119.758 122.923 131.461 1.00 48.05 ? 346 PHE A CB  1 
ATOM 298  C CG  . PHE A 1 257 ? 121.064 123.417 132.067 1.00 48.05 ? 346 PHE A CG  1 
ATOM 299  C CD1 . PHE A 1 257 ? 121.603 122.866 133.244 1.00 48.05 ? 346 PHE A CD1 1 
ATOM 300  C CD2 . PHE A 1 257 ? 121.756 124.458 131.428 1.00 48.05 ? 346 PHE A CD2 1 
ATOM 301  C CE1 . PHE A 1 257 ? 122.846 123.293 133.728 1.00 48.05 ? 346 PHE A CE1 1 
ATOM 302  C CE2 . PHE A 1 257 ? 122.994 124.900 131.920 1.00 48.05 ? 346 PHE A CE2 1 
ATOM 303  C CZ  . PHE A 1 257 ? 123.548 124.303 133.060 1.00 48.05 ? 346 PHE A CZ  1 
ATOM 304  N N   . LYS A 1 258 ? 116.751 121.287 131.987 1.00 48.31 ? 347 LYS A N   1 
ATOM 305  C CA  . LYS A 1 258 ? 115.399 121.027 131.462 1.00 48.31 ? 347 LYS A CA  1 
ATOM 306  C C   . LYS A 1 258 ? 114.392 122.059 131.939 1.00 48.31 ? 347 LYS A C   1 
ATOM 307  O O   . LYS A 1 258 ? 114.387 122.410 133.110 1.00 48.31 ? 347 LYS A O   1 
ATOM 308  C CB  . LYS A 1 258 ? 114.905 119.628 131.873 1.00 48.31 ? 347 LYS A CB  1 
ATOM 309  C CG  . LYS A 1 258 ? 115.791 118.497 131.369 1.00 48.31 ? 347 LYS A CG  1 
ATOM 310  C CD  . LYS A 1 258 ? 115.227 117.126 131.726 1.00 48.31 ? 347 LYS A CD  1 
ATOM 311  C CE  . LYS A 1 258 ? 116.185 116.038 131.252 1.00 48.31 ? 347 LYS A CE  1 
ATOM 312  N NZ  . LYS A 1 258 ? 115.665 114.678 131.485 1.00 48.31 ? 347 LYS A NZ  1 
ATOM 313  N N   . ASP A 1 259 ? 113.466 122.433 131.065 1.00 45.92 ? 348 ASP A N   1 
ATOM 314  C CA  . ASP A 1 259 ? 112.225 123.130 131.412 1.00 45.92 ? 348 ASP A CA  1 
ATOM 315  C C   . ASP A 1 259 ? 112.419 124.488 132.118 1.00 45.92 ? 348 ASP A C   1 
ATOM 316  O O   . ASP A 1 259 ? 112.460 124.572 133.340 1.00 45.92 ? 348 ASP A O   1 
ATOM 317  C CB  . ASP A 1 259 ? 111.340 122.160 132.213 1.00 45.92 ? 348 ASP A CB  1 
ATOM 318  C CG  . ASP A 1 259 ? 109.974 122.749 132.536 1.00 45.92 ? 348 ASP A CG  1 
ATOM 319  O OD1 . ASP A 1 259 ? 109.527 123.683 131.843 1.00 45.92 ? 348 ASP A OD1 1 
ATOM 320  O OD2 . ASP A 1 259 ? 109.311 122.275 133.480 1.00 45.92 ? 348 ASP A OD2 1 
ATOM 321  N N   . ARG A 1 260 ? 112.486 125.575 131.345 1.00 44.03 ? 349 ARG A N   1 
ATOM 322  C CA  . ARG A 1 260 ? 112.596 126.960 131.840 1.00 44.03 ? 349 ARG A CA  1 
ATOM 323  C C   . ARG A 1 260 ? 113.838 127.175 132.710 1.00 44.03 ? 349 ARG A C   1 
ATOM 324  O O   . ARG A 1 260 ? 113.755 127.543 133.877 1.00 44.03 ? 349 ARG A O   1 
ATOM 325  C CB  . ARG A 1 260 ? 111.274 127.399 132.500 1.00 44.03 ? 349 ARG A CB  1 
ATOM 326  C CG  . ARG A 1 260 ? 110.108 127.463 131.501 1.00 44.03 ? 349 ARG A CG  1 
ATOM 327  C CD  . ARG A 1 260 ? 108.748 127.408 132.200 1.00 44.03 ? 349 ARG A CD  1 
ATOM 328  N NE  . ARG A 1 260 ? 108.506 126.067 132.760 1.00 44.03 ? 349 ARG A NE  1 
ATOM 329  C CZ  . ARG A 1 260 ? 107.832 125.747 133.840 1.00 44.03 ? 349 ARG A CZ  1 
ATOM 330  N NH1 . ARG A 1 260 ? 107.061 126.589 134.458 1.00 44.03 ? 349 ARG A NH1 1 
ATOM 331  N NH2 . ARG A 1 260 ? 107.950 124.559 134.333 1.00 44.03 ? 349 ARG A NH2 1 
ATOM 332  N N   . VAL A 1 261 ? 115.009 126.948 132.126 1.00 42.60 ? 350 VAL A N   1 
ATOM 333  C CA  . VAL A 1 261 ? 116.311 127.245 132.735 1.00 42.60 ? 350 VAL A CA  1 
ATOM 334  C C   . VAL A 1 261 ? 116.918 128.472 132.067 1.00 42.60 ? 350 VAL A C   1 
ATOM 335  O O   . VAL A 1 261 ? 117.025 128.520 130.846 1.00 42.60 ? 350 VAL A O   1 
ATOM 336  C CB  . VAL A 1 261 ? 117.263 126.037 132.667 1.00 42.60 ? 350 VAL A CB  1 
ATOM 337  C CG1 . VAL A 1 261 ? 118.647 126.363 133.234 1.00 42.60 ? 350 VAL A CG1 1 
ATOM 338  C CG2 . VAL A 1 261 ? 116.702 124.856 133.456 1.00 42.60 ? 350 VAL A CG2 1 
ATOM 339  N N   . GLN A 1 262 ? 117.346 129.451 132.857 1.00 39.71 ? 351 GLN A N   1 
ATOM 340  C CA  . GLN A 1 262 ? 118.178 130.567 132.416 1.00 39.71 ? 351 GLN A CA  1 
ATOM 341  C C   . GLN A 1 262 ? 119.540 130.466 133.111 1.00 39.71 ? 351 GLN A C   1 
ATOM 342  O O   . GLN A 1 262 ? 119.620 130.479 134.334 1.00 39.71 ? 351 GLN A O   1 
ATOM 343  C CB  . GLN A 1 262 ? 117.431 131.874 132.699 1.00 39.71 ? 351 GLN A CB  1 
ATOM 344  C CG  . GLN A 1 262 ? 118.201 133.108 132.229 1.00 39.71 ? 351 GLN A CG  1 
ATOM 345  C CD  . GLN A 1 262 ? 117.470 134.414 132.526 1.00 39.71 ? 351 GLN A CD  1 
ATOM 346  O OE1 . GLN A 1 262 ? 118.014 135.340 133.115 1.00 39.71 ? 351 GLN A OE1 1 
ATOM 347  N NE2 . GLN A 1 262 ? 116.215 134.543 132.163 1.00 39.71 ? 351 GLN A NE2 1 
ATOM 348  N N   . SER A 1 263 ? 120.619 130.334 132.349 1.00 38.51 ? 352 SER A N   1 
ATOM 349  C CA  . SER A 1 263 ? 121.952 130.022 132.876 1.00 38.51 ? 352 SER A CA  1 
ATOM 350  C C   . SER A 1 263 ? 123.039 130.920 132.288 1.00 38.51 ? 352 SER A C   1 
ATOM 351  O O   . SER A 1 263 ? 122.940 131.362 131.144 1.00 38.51 ? 352 SER A O   1 
ATOM 352  C CB  . SER A 1 263 ? 122.258 128.544 132.650 1.00 38.51 ? 352 SER A CB  1 
ATOM 353  O OG  . SER A 1 263 ? 123.480 128.203 133.259 1.00 38.51 ? 352 SER A OG  1 
ATOM 354  N N   . LYS A 1 264 ? 124.087 131.185 133.067 1.00 36.97 ? 353 LYS A N   1 
ATOM 355  C CA  . LYS A 1 264 ? 125.262 131.974 132.688 1.00 36.97 ? 353 LYS A CA  1 
ATOM 356  C C   . LYS A 1 264 ? 126.490 131.398 133.389 1.00 36.97 ? 353 LYS A C   1 
ATOM 357  O O   . LYS A 1 264 ? 126.575 131.443 134.611 1.00 36.97 ? 353 LYS A O   1 
ATOM 358  C CB  . LYS A 1 264 ? 124.992 133.441 133.058 1.00 36.97 ? 353 LYS A CB  1 
ATOM 359  C CG  . LYS A 1 264 ? 126.048 134.399 132.507 1.00 36.97 ? 353 LYS A CG  1 
ATOM 360  C CD  . LYS A 1 264 ? 125.797 135.830 132.997 1.00 36.97 ? 353 LYS A CD  1 
ATOM 361  C CE  . LYS A 1 264 ? 126.797 136.765 132.324 1.00 36.97 ? 353 LYS A CE  1 
ATOM 362  N NZ  . LYS A 1 264 ? 126.789 138.141 132.860 1.00 36.97 ? 353 LYS A NZ  1 
ATOM 363  N N   . ILE A 1 265 ? 127.417 130.820 132.632 1.00 37.68 ? 354 ILE A N   1 
ATOM 364  C CA  . ILE A 1 265 ? 128.612 130.136 133.143 1.00 37.68 ? 354 ILE A CA  1 
ATOM 365  C C   . ILE A 1 265 ? 129.869 130.800 132.568 1.00 37.68 ? 354 ILE A C   1 
ATOM 366  O O   . ILE A 1 265 ? 130.017 130.870 131.353 1.00 37.68 ? 354 ILE A O   1 
ATOM 367  C CB  . ILE A 1 265 ? 128.544 128.618 132.842 1.00 37.68 ? 354 ILE A CB  1 
ATOM 368  C CG1 . ILE A 1 265 ? 127.304 127.977 133.499 1.00 37.68 ? 354 ILE A CG1 1 
ATOM 369  C CG2 . ILE A 1 265 ? 129.820 127.914 133.308 1.00 37.68 ? 354 ILE A CG2 1 
ATOM 370  C CD1 . ILE A 1 265 ? 127.116 126.486 133.233 1.00 37.68 ? 354 ILE A CD1 1 
ATOM 371  N N   . GLY A 1 266 ? 130.786 131.265 133.416 1.00 36.70 ? 355 GLY A N   1 
ATOM 372  C CA  . GLY A 1 266 ? 132.080 131.819 133.012 1.00 36.70 ? 355 GLY A CA  1 
ATOM 373  C C   . GLY A 1 266 ? 131.998 133.143 132.245 1.00 36.70 ? 355 GLY A C   1 
ATOM 374  O O   . GLY A 1 266 ? 132.133 133.155 131.025 1.00 36.70 ? 355 GLY A O   1 
ATOM 375  N N   . SER A 1 267 ? 131.810 134.273 132.926 1.00 35.60 ? 356 SER A N   1 
ATOM 376  C CA  . SER A 1 267 ? 131.676 135.600 132.296 1.00 35.60 ? 356 SER A CA  1 
ATOM 377  C C   . SER A 1 267 ? 132.644 136.651 132.826 1.00 35.60 ? 356 SER A C   1 
ATOM 378  O O   . SER A 1 267 ? 133.011 136.645 133.996 1.00 35.60 ? 356 SER A O   1 
ATOM 379  C CB  . SER A 1 267 ? 130.246 136.125 132.412 1.00 35.60 ? 356 SER A CB  1 
ATOM 380  O OG  . SER A 1 267 ? 129.899 136.520 133.725 1.00 35.60 ? 356 SER A OG  1 
ATOM 381  N N   . LEU A 1 268 ? 133.000 137.602 131.965 1.00 34.82 ? 357 LEU A N   1 
ATOM 382  C CA  . LEU A 1 268 ? 133.691 138.837 132.327 1.00 34.82 ? 357 LEU A CA  1 
ATOM 383  C C   . LEU A 1 268 ? 133.039 139.993 131.560 1.00 34.82 ? 357 LEU A C   1 
ATOM 384  O O   . LEU A 1 268 ? 133.507 140.380 130.492 1.00 34.82 ? 357 LEU A O   1 
ATOM 385  C CB  . LEU A 1 268 ? 135.202 138.649 132.086 1.00 34.82 ? 357 LEU A CB  1 
ATOM 386  C CG  . LEU A 1 268 ? 136.118 139.651 132.811 1.00 34.82 ? 357 LEU A CG  1 
ATOM 387  C CD1 . LEU A 1 268 ? 137.552 139.136 132.769 1.00 34.82 ? 357 LEU A CD1 1 
ATOM 388  C CD2 . LEU A 1 268 ? 136.124 141.060 132.229 1.00 34.82 ? 357 LEU A CD2 1 
ATOM 389  N N   . ASP A 1 269 ? 131.906 140.486 132.056 1.00 35.60 ? 358 ASP A N   1 
ATOM 390  C CA  . ASP A 1 269 ? 131.046 141.448 131.356 1.00 35.60 ? 358 ASP A CA  1 
ATOM 391  C C   . ASP A 1 269 ? 131.086 142.851 131.957 1.00 35.60 ? 358 ASP A C   1 
ATOM 392  O O   . ASP A 1 269 ? 130.943 143.023 133.160 1.00 35.60 ? 358 ASP A O   1 
ATOM 393  C CB  . ASP A 1 269 ? 129.594 140.964 131.325 1.00 35.60 ? 358 ASP A CB  1 
ATOM 394  C CG  . ASP A 1 269 ? 129.361 139.632 130.616 1.00 35.60 ? 358 ASP A CG  1 
ATOM 395  O OD1 . ASP A 1 269 ? 130.233 139.135 129.875 1.00 35.60 ? 358 ASP A OD1 1 
ATOM 396  O OD2 . ASP A 1 269 ? 128.238 139.104 130.763 1.00 35.60 ? 358 ASP A OD2 1 
ATOM 397  N N   . ASN A 1 270 ? 131.218 143.869 131.112 1.00 32.99 ? 359 ASN A N   1 
ATOM 398  C CA  . ASN A 1 270 ? 131.194 145.277 131.501 1.00 32.99 ? 359 ASN A CA  1 
ATOM 399  C C   . ASN A 1 270 ? 129.982 145.975 130.874 1.00 32.99 ? 359 ASN A C   1 
ATOM 400  O O   . ASN A 1 270 ? 129.792 145.885 129.664 1.00 32.99 ? 359 ASN A O   1 
ATOM 401  C CB  . ASN A 1 270 ? 132.523 145.934 131.099 1.00 32.99 ? 359 ASN A CB  1 
ATOM 402  C CG  . ASN A 1 270 ? 133.728 145.243 131.701 1.00 32.99 ? 359 ASN A CG  1 
ATOM 403  O OD1 . ASN A 1 270 ? 133.884 145.158 132.903 1.00 32.99 ? 359 ASN A OD1 1 
ATOM 404  N ND2 . ASN A 1 270 ? 134.619 144.727 130.903 1.00 32.99 ? 359 ASN A ND2 1 
ATOM 405  N N   . ILE A 1 271 ? 129.165 146.674 131.661 1.00 31.23 ? 360 ILE A N   1 
ATOM 406  C CA  . ILE A 1 271 ? 127.952 147.374 131.199 1.00 31.23 ? 360 ILE A CA  1 
ATOM 407  C C   . ILE A 1 271 ? 127.995 148.842 131.629 1.00 31.23 ? 360 ILE A C   1 
ATOM 408  O O   . ILE A 1 271 ? 128.233 149.134 132.795 1.00 31.23 ? 360 ILE A O   1 
ATOM 409  C CB  . ILE A 1 271 ? 126.667 146.671 131.714 1.00 31.23 ? 360 ILE A CB  1 
ATOM 410  C CG1 . ILE A 1 271 ? 126.602 145.192 131.276 1.00 31.23 ? 360 ILE A CG1 1 
ATOM 411  C CG2 . ILE A 1 271 ? 125.405 147.422 131.262 1.00 31.23 ? 360 ILE A CG2 1 
ATOM 412  C CD1 . ILE A 1 271 ? 125.419 144.407 131.841 1.00 31.23 ? 360 ILE A CD1 1 
ATOM 413  N N   . THR A 1 272 ? 127.710 149.772 130.723 1.00 32.74 ? 361 THR A N   1 
ATOM 414  C CA  . THR A 1 272 ? 127.420 151.179 131.046 1.00 32.74 ? 361 THR A CA  1 
ATOM 415  C C   . THR A 1 272 ? 126.022 151.526 130.560 1.00 32.74 ? 361 THR A C   1 
ATOM 416  O O   . THR A 1 272 ? 125.740 151.380 129.375 1.00 32.74 ? 361 THR A O   1 
ATOM 417  C CB  . THR A 1 272 ? 128.451 152.130 130.426 1.00 32.74 ? 361 THR A CB  1 
ATOM 418  O OG1 . THR A 1 272 ? 129.749 151.767 130.819 1.00 32.74 ? 361 THR A OG1 1 
ATOM 419  C CG2 . THR A 1 272 ? 128.264 153.573 130.874 1.00 32.74 ? 361 THR A CG2 1 
ATOM 420  N N   . HIS A 1 273 ? 125.140 151.985 131.442 1.00 34.42 ? 362 HIS A N   1 
ATOM 421  C CA  . HIS A 1 273 ? 123.728 152.217 131.139 1.00 34.42 ? 362 HIS A CA  1 
ATOM 422  C C   . HIS A 1 273 ? 123.274 153.581 131.663 1.00 34.42 ? 362 HIS A C   1 
ATOM 423  O O   . HIS A 1 273 ? 123.214 153.812 132.864 1.00 34.42 ? 362 HIS A O   1 
ATOM 424  C CB  . HIS A 1 273 ? 122.918 151.032 131.684 1.00 34.42 ? 362 HIS A CB  1 
ATOM 425  C CG  . HIS A 1 273 ? 121.462 151.047 131.304 1.00 34.42 ? 362 HIS A CG  1 
ATOM 426  N ND1 . HIS A 1 273 ? 120.941 151.508 130.098 1.00 34.42 ? 362 HIS A ND1 1 
ATOM 427  C CD2 . HIS A 1 273 ? 120.456 150.480 132.020 1.00 34.42 ? 362 HIS A CD2 1 
ATOM 428  C CE1 . HIS A 1 273 ? 119.627 151.249 130.137 1.00 34.42 ? 362 HIS A CE1 1 
ATOM 429  N NE2 . HIS A 1 273 ? 119.310 150.634 131.282 1.00 34.42 ? 362 HIS A NE2 1 
ATOM 430  N N   . VAL A 1 274 ? 123.002 154.520 130.760 1.00 35.84 ? 363 VAL A N   1 
ATOM 431  C CA  . VAL A 1 274 ? 122.712 155.923 131.094 1.00 35.84 ? 363 VAL A CA  1 
ATOM 432  C C   . VAL A 1 274 ? 121.451 156.394 130.356 1.00 35.84 ? 363 VAL A C   1 
ATOM 433  O O   . VAL A 1 274 ? 121.549 157.165 129.404 1.00 35.84 ? 363 VAL A O   1 
ATOM 434  C CB  . VAL A 1 274 ? 123.951 156.822 130.842 1.00 35.84 ? 363 VAL A CB  1 
ATOM 435  C CG1 . VAL A 1 274 ? 123.762 158.253 131.347 1.00 35.84 ? 363 VAL A CG1 1 
ATOM 436  C CG2 . VAL A 1 274 ? 125.220 156.286 131.518 1.00 35.84 ? 363 VAL A CG2 1 
ATOM 437  N N   . PRO A 1 275 ? 120.249 155.902 130.707 1.00 37.93 ? 364 PRO A N   1 
ATOM 438  C CA  . PRO A 1 275 ? 119.008 156.367 130.098 1.00 37.93 ? 364 PRO A CA  1 
ATOM 439  C C   . PRO A 1 275 ? 118.604 157.752 130.624 1.00 37.93 ? 364 PRO A C   1 
ATOM 440  O O   . PRO A 1 275 ? 118.704 158.029 131.816 1.00 37.93 ? 364 PRO A O   1 
ATOM 441  C CB  . PRO A 1 275 ? 117.972 155.290 130.426 1.00 37.93 ? 364 PRO A CB  1 
ATOM 442  C CG  . PRO A 1 275 ? 118.448 154.764 131.772 1.00 37.93 ? 364 PRO A CG  1 
ATOM 443  C CD  . PRO A 1 275 ? 119.967 154.867 131.688 1.00 37.93 ? 364 PRO A CD  1 
ATOM 444  N N   . GLY A 1 276 ? 118.076 158.616 129.760 1.00 41.42 ? 365 GLY A N   1 
ATOM 445  C CA  . GLY A 1 276 ? 117.606 159.954 130.133 1.00 41.42 ? 365 GLY A CA  1 
ATOM 446  C C   . GLY A 1 276 ? 116.376 159.965 131.046 1.00 41.42 ? 365 GLY A C   1 
ATOM 447  O O   . GLY A 1 276 ? 116.155 160.934 131.768 1.00 41.42 ? 365 GLY A O   1 
ATOM 448  N N   . GLY A 1 277 ? 115.599 158.882 131.058 1.00 43.68 ? 366 GLY A N   1 
ATOM 449  C CA  . GLY A 1 277 ? 114.507 158.636 131.995 1.00 43.68 ? 366 GLY A CA  1 
ATOM 450  C C   . GLY A 1 277 ? 114.741 157.374 132.806 1.00 43.68 ? 366 GLY A C   1 
ATOM 451  O O   . GLY A 1 277 ? 115.125 157.438 133.970 1.00 43.68 ? 366 GLY A O   1 
ATOM 452  N N   . GLY A 1 278 ? 114.534 156.210 132.198 1.00 47.09 ? 367 GLY A N   1 
ATOM 453  C CA  . GLY A 1 278 ? 114.755 154.911 132.843 1.00 47.09 ? 367 GLY A CA  1 
ATOM 454  C C   . GLY A 1 278 ? 113.729 154.548 133.918 1.00 47.09 ? 367 GLY A C   1 
ATOM 455  O O   . GLY A 1 278 ? 113.991 153.698 134.761 1.00 47.09 ? 367 GLY A O   1 
ATOM 456  N N   . ASN A 1 279 ? 112.577 155.210 133.918 1.00 49.21 ? 368 ASN A N   1 
ATOM 457  C CA  . ASN A 1 279 ? 111.458 154.928 134.811 1.00 49.21 ? 368 ASN A CA  1 
ATOM 458  C C   . ASN A 1 279 ? 110.726 153.640 134.398 1.00 49.21 ? 368 ASN A C   1 
ATOM 459  O O   . ASN A 1 279 ? 110.624 153.345 133.207 1.00 49.21 ? 368 ASN A O   1 
ATOM 460  C CB  . ASN A 1 279 ? 110.520 156.143 134.823 1.00 49.21 ? 368 ASN A CB  1 
ATOM 461  C CG  . ASN A 1 279 ? 111.202 157.394 135.319 1.00 49.21 ? 368 ASN A CG  1 
ATOM 462  O OD1 . ASN A 1 279 ? 111.811 157.412 136.373 1.00 49.21 ? 368 ASN A OD1 1 
ATOM 463  N ND2 . ASN A 1 279 ? 111.146 158.477 134.596 1.00 49.21 ? 368 ASN A ND2 1 
ATOM 464  N N   . LYS A 1 280 ? 110.191 152.887 135.363 1.00 51.15 ? 369 LYS A N   1 
ATOM 465  C CA  . LYS A 1 280 ? 109.486 151.611 135.142 1.00 51.15 ? 369 LYS A CA  1 
ATOM 466  C C   . LYS A 1 280 ? 108.122 151.581 135.820 1.00 51.15 ? 369 LYS A C   1 
ATOM 467  O O   . LYS A 1 280 ? 107.970 152.033 136.954 1.00 51.15 ? 369 LYS A O   1 
ATOM 468  C CB  . LYS A 1 280 ? 110.315 150.413 135.632 1.00 51.15 ? 369 LYS A CB  1 
ATOM 469  C CG  . LYS A 1 280 ? 111.668 150.274 134.924 1.00 51.15 ? 369 LYS A CG  1 
ATOM 470  C CD  . LYS A 1 280 ? 112.393 148.960 135.244 1.00 51.15 ? 369 LYS A CD  1 
ATOM 471  C CE  . LYS A 1 280 ? 111.640 147.738 134.699 1.00 51.15 ? 369 LYS A CE  1 
ATOM 472  N NZ  . LYS A 1 280 ? 112.468 146.513 134.754 1.00 51.15 ? 369 LYS A NZ  1 
ATOM 473  N N   . LYS A 1 281 ? 107.154 150.962 135.155 1.00 53.80 ? 370 LYS A N   1 
ATOM 474  C CA  . LYS A 1 281 ? 105.817 150.655 135.668 1.00 53.80 ? 370 LYS A CA  1 
ATOM 475  C C   . LYS A 1 281 ? 105.459 149.219 135.294 1.00 53.80 ? 370 LYS A C   1 
ATOM 476  O O   . LYS A 1 281 ? 105.592 148.849 134.132 1.00 53.80 ? 370 LYS A O   1 
ATOM 477  C CB  . LYS A 1 281 ? 104.853 151.701 135.099 1.00 53.80 ? 370 LYS A CB  1 
ATOM 478  C CG  . LYS A 1 281 ? 103.371 151.450 135.403 1.00 53.80 ? 370 LYS A CG  1 
ATOM 479  C CD  . LYS A 1 281 ? 102.552 152.609 134.815 1.00 53.80 ? 370 LYS A CD  1 
ATOM 480  C CE  . LYS A 1 281 ? 101.049 152.328 134.706 1.00 53.80 ? 370 LYS A CE  1 
ATOM 481  N NZ  . LYS A 1 281 ? 100.380 152.275 136.022 1.00 53.80 ? 370 LYS A NZ  1 
ATOM 482  N N   . ILE A 1 282 ? 105.010 148.415 136.253 1.00 55.47 ? 371 ILE A N   1 
ATOM 483  C CA  . ILE A 1 282 ? 104.646 147.004 136.039 1.00 55.47 ? 371 ILE A CA  1 
ATOM 484  C C   . ILE A 1 282 ? 103.265 146.753 136.625 1.00 55.47 ? 371 ILE A C   1 
ATOM 485  O O   . ILE A 1 282 ? 102.991 147.113 137.763 1.00 55.47 ? 371 ILE A O   1 
ATOM 486  C CB  . ILE A 1 282 ? 105.704 146.033 136.615 1.00 55.47 ? 371 ILE A CB  1 
ATOM 487  C CG1 . ILE A 1 282 ? 107.079 146.263 135.954 1.00 55.47 ? 371 ILE A CG1 1 
ATOM 488  C CG2 . ILE A 1 282 ? 105.267 144.570 136.437 1.00 55.47 ? 371 ILE A CG2 1 
ATOM 489  C CD1 . ILE A 1 282 ? 108.217 145.411 136.516 1.00 55.47 ? 371 ILE A CD1 1 
ATOM 490  N N   . GLU A 1 283 ? 102.412 146.104 135.846 1.00 58.60 ? 372 GLU A N   1 
ATOM 491  C CA  . GLU A 1 283 ? 101.020 145.794 136.166 1.00 58.60 ? 372 GLU A CA  1 
ATOM 492  C C   . GLU A 1 283 ? 100.762 144.300 135.958 1.00 58.60 ? 372 GLU A C   1 
ATOM 493  O O   . GLU A 1 283 ? 101.369 143.667 135.095 1.00 58.60 ? 372 GLU A O   1 
ATOM 494  C CB  . GLU A 1 283 ? 100.084 146.594 135.250 1.00 58.60 ? 372 GLU A CB  1 
ATOM 495  C CG  . GLU A 1 283 ? 100.266 148.119 135.281 1.00 58.60 ? 372 GLU A CG  1 
ATOM 496  C CD  . GLU A 1 283 ? 99.803  148.777 136.588 1.00 58.60 ? 372 GLU A CD  1 
ATOM 497  O OE1 . GLU A 1 283 ? 98.762  148.351 137.139 1.00 58.60 ? 372 GLU A OE1 1 
ATOM 498  O OE2 . GLU A 1 283 ? 100.439 149.777 136.995 1.00 58.60 ? 372 GLU A OE2 1 
ATOM 499  N N   . THR A 1 284 ? 99.860  143.703 136.730 1.00 61.89 ? 373 THR A N   1 
ATOM 500  C CA  . THR A 1 284 ? 99.458  142.295 136.591 1.00 61.89 ? 373 THR A CA  1 
ATOM 501  C C   . THR A 1 284 ? 98.052  142.131 137.145 1.00 61.89 ? 373 THR A C   1 
ATOM 502  O O   . THR A 1 284 ? 97.828  142.355 138.331 1.00 61.89 ? 373 THR A O   1 
ATOM 503  C CB  . THR A 1 284 ? 100.465 141.377 137.308 1.00 61.89 ? 373 THR A CB  1 
ATOM 504  O OG1 . THR A 1 284 ? 101.619 141.263 136.510 1.00 61.89 ? 373 THR A OG1 1 
ATOM 505  C CG2 . THR A 1 284 ? 99.993  139.947 137.545 1.00 61.89 ? 373 THR A CG2 1 
ATOM 506  N N   . HIS A 1 285 ? 97.107  141.749 136.289 1.00 64.71 ? 374 HIS A N   1 
ATOM 507  C CA  . HIS A 1 285 ? 95.720  141.442 136.643 1.00 64.71 ? 374 HIS A CA  1 
ATOM 508  C C   . HIS A 1 285 ? 95.456  139.954 136.439 1.00 64.71 ? 374 HIS A C   1 
ATOM 509  O O   . HIS A 1 285 ? 95.742  139.434 135.361 1.00 64.71 ? 374 HIS A O   1 
ATOM 510  C CB  . HIS A 1 285 ? 94.757  142.251 135.764 1.00 64.71 ? 374 HIS A CB  1 
ATOM 511  C CG  . HIS A 1 285 ? 94.897  143.748 135.862 1.00 64.71 ? 374 HIS A CG  1 
ATOM 512  N ND1 . HIS A 1 285 ? 94.463  144.537 136.925 1.00 64.71 ? 374 HIS A ND1 1 
ATOM 513  C CD2 . HIS A 1 285 ? 95.404  144.562 134.895 1.00 64.71 ? 374 HIS A CD2 1 
ATOM 514  C CE1 . HIS A 1 285 ? 94.719  145.806 136.577 1.00 64.71 ? 374 HIS A CE1 1 
ATOM 515  N NE2 . HIS A 1 285 ? 95.288  145.848 135.365 1.00 64.71 ? 374 HIS A NE2 1 
ATOM 516  N N   . LYS A 1 286 ? 94.899  139.259 137.431 1.00 69.21 ? 375 LYS A N   1 
ATOM 517  C CA  . LYS A 1 286 ? 94.498  137.849 137.302 1.00 69.21 ? 375 LYS A CA  1 
ATOM 518  C C   . LYS A 1 286 ? 93.148  137.571 137.961 1.00 69.21 ? 375 LYS A C   1 
ATOM 519  O O   . LYS A 1 286 ? 92.849  138.114 139.027 1.00 69.21 ? 375 LYS A O   1 
ATOM 520  C CB  . LYS A 1 286 ? 95.642  136.960 137.818 1.00 69.21 ? 375 LYS A CB  1 
ATOM 521  C CG  . LYS A 1 286 ? 95.392  135.465 137.570 1.00 69.21 ? 375 LYS A CG  1 
ATOM 522  C CD  . LYS A 1 286 ? 96.666  134.608 137.625 1.00 69.21 ? 375 LYS A CD  1 
ATOM 523  C CE  . LYS A 1 286 ? 97.563  134.878 136.408 1.00 69.21 ? 375 LYS A CE  1 
ATOM 524  N NZ  . LYS A 1 286 ? 98.772  134.021 136.401 1.00 69.21 ? 375 LYS A NZ  1 
ATOM 525  N N   . LEU A 1 287 ? 92.353  136.717 137.321 1.00 73.49 ? 376 LEU A N   1 
ATOM 526  C CA  . LEU A 1 287 ? 91.072  136.197 137.803 1.00 73.49 ? 376 LEU A CA  1 
ATOM 527  C C   . LEU A 1 287 ? 91.004  134.690 137.522 1.00 73.49 ? 376 LEU A C   1 
ATOM 528  O O   . LEU A 1 287 ? 91.226  134.274 136.387 1.00 73.49 ? 376 LEU A O   1 
ATOM 529  C CB  . LEU A 1 287 ? 89.940  136.994 137.127 1.00 73.49 ? 376 LEU A CB  1 
ATOM 530  C CG  . LEU A 1 287 ? 88.521  136.429 137.314 1.00 73.49 ? 376 LEU A CG  1 
ATOM 531  C CD1 . LEU A 1 287 ? 88.109  136.299 138.777 1.00 73.49 ? 376 LEU A CD1 1 
ATOM 532  C CD2 . LEU A 1 287 ? 87.513  137.367 136.652 1.00 73.49 ? 376 LEU A CD2 1 
ATOM 533  N N   . THR A 1 288 ? 90.693  133.876 138.533 1.00 77.93 ? 377 THR A N   1 
ATOM 534  C CA  . THR A 1 288 ? 90.749  132.402 138.457 1.00 77.93 ? 377 THR A CA  1 
ATOM 535  C C   . THR A 1 288 ? 89.518  131.733 139.071 1.00 77.93 ? 377 THR A C   1 
ATOM 536  O O   . THR A 1 288 ? 89.104  132.086 140.174 1.00 77.93 ? 377 THR A O   1 
ATOM 537  C CB  . THR A 1 288 ? 92.025  131.891 139.153 1.00 77.93 ? 377 THR A CB  1 
ATOM 538  O OG1 . THR A 1 288 ? 93.172  132.395 138.509 1.00 77.93 ? 377 THR A OG1 1 
ATOM 539  C CG2 . THR A 1 288 ? 92.183  130.372 139.169 1.00 77.93 ? 377 THR A CG2 1 
ATOM 540  N N   . PHE A 1 289 ? 88.996  130.701 138.405 1.00 82.27 ? 378 PHE A N   1 
ATOM 541  C CA  . PHE A 1 289 ? 87.951  129.800 138.911 1.00 82.27 ? 378 PHE A CA  1 
ATOM 542  C C   . PHE A 1 289 ? 88.472  128.365 139.058 1.00 82.27 ? 378 PHE A C   1 
ATOM 543  O O   . PHE A 1 289 ? 89.207  127.864 138.202 1.00 82.27 ? 378 PHE A O   1 
ATOM 544  C CB  . PHE A 1 289 ? 86.722  129.850 137.996 1.00 82.27 ? 378 PHE A CB  1 
ATOM 545  C CG  . PHE A 1 289 ? 86.005  131.185 137.994 1.00 82.27 ? 378 PHE A CG  1 
ATOM 546  C CD1 . PHE A 1 289 ? 86.419  132.204 137.119 1.00 82.27 ? 378 PHE A CD1 1 
ATOM 547  C CD2 . PHE A 1 289 ? 84.934  131.418 138.877 1.00 82.27 ? 378 PHE A CD2 1 
ATOM 548  C CE1 . PHE A 1 289 ? 85.778  133.453 137.134 1.00 82.27 ? 378 PHE A CE1 1 
ATOM 549  C CE2 . PHE A 1 289 ? 84.289  132.667 138.891 1.00 82.27 ? 378 PHE A CE2 1 
ATOM 550  C CZ  . PHE A 1 289 ? 84.713  133.687 138.021 1.00 82.27 ? 378 PHE A CZ  1 
ATOM 551  N N   . GLN B 1 218 ? 77.341  139.169 149.272 1.00 79.40 ? 307 GLN B N   1 
ATOM 552  C CA  . GLN B 1 218 ? 77.768  140.391 148.592 1.00 79.40 ? 307 GLN B CA  1 
ATOM 553  C C   . GLN B 1 218 ? 79.138  140.857 149.108 1.00 79.40 ? 307 GLN B C   1 
ATOM 554  O O   . GLN B 1 218 ? 79.315  141.011 150.316 1.00 79.40 ? 307 GLN B O   1 
ATOM 555  C CB  . GLN B 1 218 ? 76.696  141.479 148.794 1.00 79.40 ? 307 GLN B CB  1 
ATOM 556  C CG  . GLN B 1 218 ? 77.047  142.811 148.104 1.00 79.40 ? 307 GLN B CG  1 
ATOM 557  C CD  . GLN B 1 218 ? 75.971  143.889 148.256 1.00 79.40 ? 307 GLN B CD  1 
ATOM 558  O OE1 . GLN B 1 218 ? 75.038  143.798 149.046 1.00 79.40 ? 307 GLN B OE1 1 
ATOM 559  N NE2 . GLN B 1 218 ? 76.061  144.967 147.513 1.00 79.40 ? 307 GLN B NE2 1 
ATOM 560  N N   . ILE B 1 219 ? 80.095  141.120 148.212 1.00 76.56 ? 308 ILE B N   1 
ATOM 561  C CA  . ILE B 1 219 ? 81.420  141.668 148.544 1.00 76.56 ? 308 ILE B CA  1 
ATOM 562  C C   . ILE B 1 219 ? 81.720  142.888 147.662 1.00 76.56 ? 308 ILE B C   1 
ATOM 563  O O   . ILE B 1 219 ? 81.571  142.837 146.443 1.00 76.56 ? 308 ILE B O   1 
ATOM 564  C CB  . ILE B 1 219 ? 82.518  140.576 148.460 1.00 76.56 ? 308 ILE B CB  1 
ATOM 565  C CG1 . ILE B 1 219 ? 82.340  139.467 149.526 1.00 76.56 ? 308 ILE B CG1 1 
ATOM 566  C CG2 . ILE B 1 219 ? 83.919  141.193 148.632 1.00 76.56 ? 308 ILE B CG2 1 
ATOM 567  C CD1 . ILE B 1 219 ? 81.458  138.294 149.080 1.00 76.56 ? 308 ILE B CD1 1 
ATOM 568  N N   . VAL B 1 220 ? 82.173  143.980 148.283 1.00 72.40 ? 309 VAL B N   1 
ATOM 569  C CA  . VAL B 1 220 ? 82.507  145.257 147.632 1.00 72.40 ? 309 VAL B CA  1 
ATOM 570  C C   . VAL B 1 220 ? 83.954  145.646 147.942 1.00 72.40 ? 309 VAL B C   1 
ATOM 571  O O   . VAL B 1 220 ? 84.237  146.385 148.884 1.00 72.40 ? 309 VAL B O   1 
ATOM 572  C CB  . VAL B 1 220 ? 81.481  146.353 147.988 1.00 72.40 ? 309 VAL B CB  1 
ATOM 573  C CG1 . VAL B 1 220 ? 81.731  147.630 147.183 1.00 72.40 ? 309 VAL B CG1 1 
ATOM 574  C CG2 . VAL B 1 220 ? 80.048  145.901 147.675 1.00 72.40 ? 309 VAL B CG2 1 
ATOM 575  N N   . TYR B 1 221 ? 84.895  145.083 147.191 1.00 69.33 ? 310 TYR B N   1 
ATOM 576  C CA  . TYR B 1 221 ? 86.322  145.328 147.366 1.00 69.33 ? 310 TYR B CA  1 
ATOM 577  C C   . TYR B 1 221 ? 86.715  146.603 146.604 1.00 69.33 ? 310 TYR B C   1 
ATOM 578  O O   . TYR B 1 221 ? 86.918  146.576 145.390 1.00 69.33 ? 310 TYR B O   1 
ATOM 579  C CB  . TYR B 1 221 ? 87.066  144.077 146.889 1.00 69.33 ? 310 TYR B CB  1 
ATOM 580  C CG  . TYR B 1 221 ? 88.547  144.060 147.191 1.00 69.33 ? 310 TYR B CG  1 
ATOM 581  C CD1 . TYR B 1 221 ? 89.467  144.621 146.287 1.00 69.33 ? 310 TYR B CD1 1 
ATOM 582  C CD2 . TYR B 1 221 ? 89.007  143.416 148.355 1.00 69.33 ? 310 TYR B CD2 1 
ATOM 583  C CE1 . TYR B 1 221 ? 90.847  144.536 146.544 1.00 69.33 ? 310 TYR B CE1 1 
ATOM 584  C CE2 . TYR B 1 221 ? 90.384  143.319 148.610 1.00 69.33 ? 310 TYR B CE2 1 
ATOM 585  C CZ  . TYR B 1 221 ? 91.306  143.870 147.700 1.00 69.33 ? 310 TYR B CZ  1 
ATOM 586  O OH  . TYR B 1 221 ? 92.631  143.756 147.952 1.00 69.33 ? 310 TYR B OH  1 
ATOM 587  N N   . LYS B 1 222 ? 86.812  147.736 147.307 1.00 65.39 ? 311 LYS B N   1 
ATOM 588  C CA  . LYS B 1 222 ? 86.909  149.076 146.696 1.00 65.39 ? 311 LYS B CA  1 
ATOM 589  C C   . LYS B 1 222 ? 87.899  150.012 147.425 1.00 65.39 ? 311 LYS B C   1 
ATOM 590  O O   . LYS B 1 222 ? 87.512  151.099 147.856 1.00 65.39 ? 311 LYS B O   1 
ATOM 591  C CB  . LYS B 1 222 ? 85.475  149.645 146.602 1.00 65.39 ? 311 LYS B CB  1 
ATOM 592  C CG  . LYS B 1 222 ? 85.332  150.825 145.628 1.00 65.39 ? 311 LYS B CG  1 
ATOM 593  C CD  . LYS B 1 222 ? 83.875  151.297 145.546 1.00 65.39 ? 311 LYS B CD  1 
ATOM 594  C CE  . LYS B 1 222 ? 83.738  152.437 144.529 1.00 65.39 ? 311 LYS B CE  1 
ATOM 595  N NZ  . LYS B 1 222 ? 82.337  152.918 144.448 1.00 65.39 ? 311 LYS B NZ  1 
ATOM 596  N N   . PRO B 1 223 ? 89.174  149.622 147.613 1.00 63.67 ? 312 PRO B N   1 
ATOM 597  C CA  . PRO B 1 223 ? 90.199  150.518 148.144 1.00 63.67 ? 312 PRO B CA  1 
ATOM 598  C C   . PRO B 1 223 ? 90.479  151.691 147.192 1.00 63.67 ? 312 PRO B C   1 
ATOM 599  O O   . PRO B 1 223 ? 90.346  151.558 145.977 1.00 63.67 ? 312 PRO B O   1 
ATOM 600  C CB  . PRO B 1 223 ? 91.439  149.649 148.361 1.00 63.67 ? 312 PRO B CB  1 
ATOM 601  C CG  . PRO B 1 223 ? 91.288  148.580 147.288 1.00 63.67 ? 312 PRO B CG  1 
ATOM 602  C CD  . PRO B 1 223 ? 89.780  148.357 147.225 1.00 63.67 ? 312 PRO B CD  1 
ATOM 603  N N   . VAL B 1 224 ? 90.921  152.826 147.734 1.00 61.45 ? 313 VAL B N   1 
ATOM 604  C CA  . VAL B 1 224 ? 91.287  154.032 146.969 1.00 61.45 ? 313 VAL B CA  1 
ATOM 605  C C   . VAL B 1 224 ? 92.691  154.495 147.362 1.00 61.45 ? 313 VAL B C   1 
ATOM 606  O O   . VAL B 1 224 ? 92.989  154.625 148.547 1.00 61.45 ? 313 VAL B O   1 
ATOM 607  C CB  . VAL B 1 224 ? 90.246  155.150 147.176 1.00 61.45 ? 313 VAL B CB  1 
ATOM 608  C CG1 . VAL B 1 224 ? 90.631  156.463 146.483 1.00 61.45 ? 313 VAL B CG1 1 
ATOM 609  C CG2 . VAL B 1 224 ? 88.867  154.726 146.659 1.00 61.45 ? 313 VAL B CG2 1 
ATOM 610  N N   . ASP B 1 225 ? 93.553  154.780 146.387 1.00 58.83 ? 314 ASP B N   1 
ATOM 611  C CA  . ASP B 1 225 ? 94.921  155.266 146.607 1.00 58.83 ? 314 ASP B CA  1 
ATOM 612  C C   . ASP B 1 225 ? 95.123  156.646 145.959 1.00 58.83 ? 314 ASP B C   1 
ATOM 613  O O   . ASP B 1 225 ? 94.945  156.812 144.757 1.00 58.83 ? 314 ASP B O   1 
ATOM 614  C CB  . ASP B 1 225 ? 95.918  154.206 146.098 1.00 58.83 ? 314 ASP B CB  1 
ATOM 615  C CG  . ASP B 1 225 ? 97.400  154.599 146.227 1.00 58.83 ? 314 ASP B CG  1 
ATOM 616  O OD1 . ASP B 1 225 ? 97.726  155.625 146.864 1.00 58.83 ? 314 ASP B OD1 1 
ATOM 617  O OD2 . ASP B 1 225 ? 98.268  153.821 145.777 1.00 58.83 ? 314 ASP B OD2 1 
ATOM 618  N N   . LEU B 1 226 ? 95.550  157.616 146.769 1.00 56.80 ? 315 LEU B N   1 
ATOM 619  C CA  . LEU B 1 226 ? 95.779  159.030 146.446 1.00 56.80 ? 315 LEU B CA  1 
ATOM 620  C C   . LEU B 1 226 ? 97.208  159.480 146.809 1.00 56.80 ? 315 LEU B C   1 
ATOM 621  O O   . LEU B 1 226 ? 97.515  160.672 146.802 1.00 56.80 ? 315 LEU B O   1 
ATOM 622  C CB  . LEU B 1 226 ? 94.740  159.874 147.214 1.00 56.80 ? 315 LEU B CB  1 
ATOM 623  C CG  . LEU B 1 226 ? 93.277  159.678 146.782 1.00 56.80 ? 315 LEU B CG  1 
ATOM 624  C CD1 . LEU B 1 226 ? 92.321  160.145 147.876 1.00 56.80 ? 315 LEU B CD1 1 
ATOM 625  C CD2 . LEU B 1 226 ? 92.980  160.530 145.551 1.00 56.80 ? 315 LEU B CD2 1 
ATOM 626  N N   . SER B 1 227 ? 98.074  158.532 147.168 1.00 55.49 ? 316 SER B N   1 
ATOM 627  C CA  . SER B 1 227 ? 99.413  158.774 147.718 1.00 55.49 ? 316 SER B CA  1 
ATOM 628  C C   . SER B 1 227 ? 100.410 159.435 146.754 1.00 55.49 ? 316 SER B C   1 
ATOM 629  O O   . SER B 1 227 ? 100.265 159.372 145.532 1.00 55.49 ? 316 SER B O   1 
ATOM 630  C CB  . SER B 1 227 ? 99.964  157.457 148.268 1.00 55.49 ? 316 SER B CB  1 
ATOM 631  O OG  . SER B 1 227 ? 100.105 156.499 147.236 1.00 55.49 ? 316 SER B OG  1 
ATOM 632  N N   . LYS B 1 228 ? 101.466 160.035 147.308 1.00 53.46 ? 317 LYS B N   1 
ATOM 633  C CA  . LYS B 1 228 ? 102.564 160.656 146.551 1.00 53.46 ? 317 LYS B CA  1 
ATOM 634  C C   . LYS B 1 228 ? 103.895 160.085 147.053 1.00 53.46 ? 317 LYS B C   1 
ATOM 635  O O   . LYS B 1 228 ? 104.090 159.961 148.260 1.00 53.46 ? 317 LYS B O   1 
ATOM 636  C CB  . LYS B 1 228 ? 102.605 162.183 146.772 1.00 53.46 ? 317 LYS B CB  1 
ATOM 637  C CG  . LYS B 1 228 ? 101.303 162.971 146.572 1.00 53.46 ? 317 LYS B CG  1 
ATOM 638  C CD  . LYS B 1 228 ? 100.738 162.956 145.149 1.00 53.46 ? 317 LYS B CD  1 
ATOM 639  C CE  . LYS B 1 228 ? 99.543  163.917 145.034 1.00 53.46 ? 317 LYS B CE  1 
ATOM 640  N NZ  . LYS B 1 228 ? 98.289  163.376 145.620 1.00 53.46 ? 317 LYS B NZ  1 
ATOM 641  N N   . VAL B 1 229 ? 104.836 159.808 146.154 1.00 52.45 ? 318 VAL B N   1 
ATOM 642  C CA  . VAL B 1 229 ? 106.252 159.580 146.489 1.00 52.45 ? 318 VAL B CA  1 
ATOM 643  C C   . VAL B 1 229 ? 107.095 160.524 145.641 1.00 52.45 ? 318 VAL B C   1 
ATOM 644  O O   . VAL B 1 229 ? 106.924 160.583 144.427 1.00 52.45 ? 318 VAL B O   1 
ATOM 645  C CB  . VAL B 1 229 ? 106.656 158.108 146.312 1.00 52.45 ? 318 VAL B CB  1 
ATOM 646  C CG1 . VAL B 1 229 ? 108.075 157.872 146.823 1.00 52.45 ? 318 VAL B CG1 1 
ATOM 647  C CG2 . VAL B 1 229 ? 105.724 157.154 147.053 1.00 52.45 ? 318 VAL B CG2 1 
ATOM 648  N N   . THR B 1 230 ? 107.927 161.363 146.244 1.00 52.09 ? 319 THR B N   1 
ATOM 649  C CA  . THR B 1 230 ? 108.553 162.509 145.560 1.00 52.09 ? 319 THR B CA  1 
ATOM 650  C C   . THR B 1 230 ? 109.956 162.794 146.084 1.00 52.09 ? 319 THR B C   1 
ATOM 651  O O   . THR B 1 230 ? 110.243 162.552 147.253 1.00 52.09 ? 319 THR B O   1 
ATOM 652  C CB  . THR B 1 230 ? 107.634 163.739 145.681 1.00 52.09 ? 319 THR B CB  1 
ATOM 653  O OG1 . THR B 1 230 ? 106.443 163.495 144.972 1.00 52.09 ? 319 THR B OG1 1 
ATOM 654  C CG2 . THR B 1 230 ? 108.174 165.043 145.098 1.00 52.09 ? 319 THR B CG2 1 
ATOM 655  N N   . SER B 1 231 ? 110.816 163.370 145.244 1.00 49.98 ? 320 SER B N   1 
ATOM 656  C CA  . SER B 1 231 ? 112.138 163.874 145.638 1.00 49.98 ? 320 SER B CA  1 
ATOM 657  C C   . SER B 1 231 ? 112.534 165.094 144.820 1.00 49.98 ? 320 SER B C   1 
ATOM 658  O O   . SER B 1 231 ? 112.181 165.203 143.646 1.00 49.98 ? 320 SER B O   1 
ATOM 659  C CB  . SER B 1 231 ? 113.228 162.821 145.411 1.00 49.98 ? 320 SER B CB  1 
ATOM 660  O OG  . SER B 1 231 ? 112.921 161.613 146.060 1.00 49.98 ? 320 SER B OG  1 
ATOM 661  N N   . LYS B 1 232 ? 113.352 165.960 145.413 1.00 47.86 ? 321 LYS B N   1 
ATOM 662  C CA  . LYS B 1 232 ? 114.067 167.050 144.745 1.00 47.86 ? 321 LYS B CA  1 
ATOM 663  C C   . LYS B 1 232 ? 115.541 166.975 145.137 1.00 47.86 ? 321 LYS B C   1 
ATOM 664  O O   . LYS B 1 232 ? 115.845 166.795 146.314 1.00 47.86 ? 321 LYS B O   1 
ATOM 665  C CB  . LYS B 1 232 ? 113.456 168.397 145.154 1.00 47.86 ? 321 LYS B CB  1 
ATOM 666  C CG  . LYS B 1 232 ? 112.006 168.554 144.683 1.00 47.86 ? 321 LYS B CG  1 
ATOM 667  C CD  . LYS B 1 232 ? 111.492 169.960 144.995 1.00 47.86 ? 321 LYS B CD  1 
ATOM 668  C CE  . LYS B 1 232 ? 110.051 170.135 144.517 1.00 47.86 ? 321 LYS B CE  1 
ATOM 669  N NZ  . LYS B 1 232 ? 109.595 171.531 144.687 1.00 47.86 ? 321 LYS B NZ  1 
ATOM 670  N N   . CYS B 1 233 ? 116.453 167.110 144.183 1.00 47.04 ? 322 CYS B N   1 
ATOM 671  C CA  . CYS B 1 233 ? 117.894 167.140 144.423 1.00 47.04 ? 322 CYS B CA  1 
ATOM 672  C C   . CYS B 1 233 ? 118.557 168.256 143.597 1.00 47.04 ? 322 CYS B C   1 
ATOM 673  O O   . CYS B 1 233 ? 118.365 168.334 142.384 1.00 47.04 ? 322 CYS B O   1 
ATOM 674  C CB  . CYS B 1 233 ? 118.447 165.738 144.127 1.00 47.04 ? 322 CYS B CB  1 
ATOM 675  S SG  . CYS B 1 233 ? 120.225 165.650 144.454 1.00 47.04 ? 322 CYS B SG  1 
ATOM 676  N N   . GLY B 1 234 ? 119.339 169.132 144.229 1.00 45.03 ? 323 GLY B N   1 
ATOM 677  C CA  . GLY B 1 234 ? 119.881 170.325 143.569 1.00 45.03 ? 323 GLY B CA  1 
ATOM 678  C C   . GLY B 1 234 ? 121.034 170.044 142.601 1.00 45.03 ? 323 GLY B C   1 
ATOM 679  O O   . GLY B 1 234 ? 121.150 170.690 141.561 1.00 45.03 ? 323 GLY B O   1 
ATOM 680  N N   . SER B 1 235 ? 121.880 169.072 142.927 1.00 43.18 ? 324 SER B N   1 
ATOM 681  C CA  . SER B 1 235 ? 122.979 168.566 142.100 1.00 43.18 ? 324 SER B CA  1 
ATOM 682  C C   . SER B 1 235 ? 123.486 167.244 142.671 1.00 43.18 ? 324 SER B C   1 
ATOM 683  O O   . SER B 1 235 ? 123.628 167.126 143.889 1.00 43.18 ? 324 SER B O   1 
ATOM 684  C CB  . SER B 1 235 ? 124.126 169.574 142.072 1.00 43.18 ? 324 SER B CB  1 
ATOM 685  O OG  . SER B 1 235 ? 125.152 169.108 141.223 1.00 43.18 ? 324 SER B OG  1 
ATOM 686  N N   . LEU B 1 236 ? 123.780 166.263 141.824 1.00 41.17 ? 325 LEU B N   1 
ATOM 687  C CA  . LEU B 1 236 ? 124.201 164.926 142.232 1.00 41.17 ? 325 LEU B CA  1 
ATOM 688  C C   . LEU B 1 236 ? 125.442 164.513 141.432 1.00 41.17 ? 325 LEU B C   1 
ATOM 689  O O   . LEU B 1 236 ? 125.391 164.376 140.215 1.00 41.17 ? 325 LEU B O   1 
ATOM 690  C CB  . LEU B 1 236 ? 122.982 163.996 142.067 1.00 41.17 ? 325 LEU B CB  1 
ATOM 691  C CG  . LEU B 1 236 ? 123.210 162.514 142.387 1.00 41.17 ? 325 LEU B CG  1 
ATOM 692  C CD1 . LEU B 1 236 ? 123.731 162.302 143.806 1.00 41.17 ? 325 LEU B CD1 1 
ATOM 693  C CD2 . LEU B 1 236 ? 121.881 161.767 142.280 1.00 41.17 ? 325 LEU B CD2 1 
ATOM 694  N N   . GLY B 1 237 ? 126.577 164.316 142.099 1.00 37.60 ? 326 GLY B N   1 
ATOM 695  C CA  . GLY B 1 237 ? 127.829 164.037 141.400 1.00 37.60 ? 326 GLY B CA  1 
ATOM 696  C C   . GLY B 1 237 ? 129.089 164.070 142.253 1.00 37.60 ? 326 GLY B C   1 
ATOM 697  O O   . GLY B 1 237 ? 129.019 164.142 143.477 1.00 37.60 ? 326 GLY B O   1 
ATOM 698  N N   . ASN B 1 238 ? 130.246 164.027 141.586 1.00 34.69 ? 327 ASN B N   1 
ATOM 699  C CA  . ASN B 1 238 ? 131.579 163.858 142.180 1.00 34.69 ? 327 ASN B CA  1 
ATOM 700  C C   . ASN B 1 238 ? 131.679 162.544 142.973 1.00 34.69 ? 327 ASN B C   1 
ATOM 701  O O   . ASN B 1 238 ? 131.984 162.533 144.163 1.00 34.69 ? 327 ASN B O   1 
ATOM 702  C CB  . ASN B 1 238 ? 131.989 165.122 142.959 1.00 34.69 ? 327 ASN B CB  1 
ATOM 703  C CG  . ASN B 1 238 ? 133.455 165.135 143.352 1.00 34.69 ? 327 ASN B CG  1 
ATOM 704  O OD1 . ASN B 1 238 ? 134.306 164.498 142.750 1.00 34.69 ? 327 ASN B OD1 1 
ATOM 705  N ND2 . ASN B 1 238 ? 133.806 165.858 144.385 1.00 34.69 ? 327 ASN B ND2 1 
ATOM 706  N N   . ILE B 1 239 ? 131.359 161.429 142.314 1.00 33.92 ? 328 ILE B N   1 
ATOM 707  C CA  . ILE B 1 239 ? 131.310 160.087 142.910 1.00 33.92 ? 328 ILE B CA  1 
ATOM 708  C C   . ILE B 1 239 ? 132.409 159.221 142.293 1.00 33.92 ? 328 ILE B C   1 
ATOM 709  O O   . ILE B 1 239 ? 132.487 159.082 141.077 1.00 33.92 ? 328 ILE B O   1 
ATOM 710  C CB  . ILE B 1 239 ? 129.903 159.472 142.747 1.00 33.92 ? 328 ILE B CB  1 
ATOM 711  C CG1 . ILE B 1 239 ? 128.853 160.260 143.557 1.00 33.92 ? 328 ILE B CG1 1 
ATOM 712  C CG2 . ILE B 1 239 ? 129.856 157.999 143.179 1.00 33.92 ? 328 ILE B CG2 1 
ATOM 713  C CD1 . ILE B 1 239 ? 127.458 160.219 142.933 1.00 33.92 ? 328 ILE B CD1 1 
ATOM 714  N N   . HIS B 1 240 ? 133.249 158.619 143.128 1.00 32.69 ? 329 HIS B N   1 
ATOM 715  C CA  . HIS B 1 240 ? 134.374 157.779 142.715 1.00 32.69 ? 329 HIS B CA  1 
ATOM 716  C C   . HIS B 1 240 ? 134.231 156.387 143.314 1.00 32.69 ? 329 HIS B C   1 
ATOM 717  O O   . HIS B 1 240 ? 134.206 156.251 144.532 1.00 32.69 ? 329 HIS B O   1 
ATOM 718  C CB  . HIS B 1 240 ? 135.689 158.436 143.159 1.00 32.69 ? 329 HIS B CB  1 
ATOM 719  C CG  . HIS B 1 240 ? 135.897 159.834 142.633 1.00 32.69 ? 329 HIS B CG  1 
ATOM 720  N ND1 . HIS B 1 240 ? 136.534 160.165 141.439 1.00 32.69 ? 329 HIS B ND1 1 
ATOM 721  C CD2 . HIS B 1 240 ? 135.403 160.973 143.192 1.00 32.69 ? 329 HIS B CD2 1 
ATOM 722  C CE1 . HIS B 1 240 ? 136.404 161.494 141.310 1.00 32.69 ? 329 HIS B CE1 1 
ATOM 723  N NE2 . HIS B 1 240 ? 135.725 162.003 142.345 1.00 32.69 ? 329 HIS B NE2 1 
ATOM 724  N N   . HIS B 1 241 ? 134.160 155.344 142.493 1.00 32.07 ? 330 HIS B N   1 
ATOM 725  C CA  . HIS B 1 241 ? 134.163 153.950 142.942 1.00 32.07 ? 330 HIS B CA  1 
ATOM 726  C C   . HIS B 1 241 ? 135.375 153.224 142.355 1.00 32.07 ? 330 HIS B C   1 
ATOM 727  O O   . HIS B 1 241 ? 135.483 153.055 141.142 1.00 32.07 ? 330 HIS B O   1 
ATOM 728  C CB  . HIS B 1 241 ? 132.830 153.300 142.558 1.00 32.07 ? 330 HIS B CB  1 
ATOM 729  C CG  . HIS B 1 241 ? 132.631 151.880 143.031 1.00 32.07 ? 330 HIS B CG  1 
ATOM 730  N ND1 . HIS B 1 241 ? 131.662 151.035 142.566 1.00 32.07 ? 330 HIS B ND1 1 
ATOM 731  C CD2 . HIS B 1 241 ? 133.235 151.235 144.074 1.00 32.07 ? 330 HIS B CD2 1 
ATOM 732  C CE1 . HIS B 1 241 ? 131.685 149.904 143.278 1.00 32.07 ? 330 HIS B CE1 1 
ATOM 733  N NE2 . HIS B 1 241 ? 132.630 149.982 144.222 1.00 32.07 ? 330 HIS B NE2 1 
ATOM 734  N N   . LYS B 1 242 ? 136.301 152.794 143.211 1.00 31.44 ? 331 LYS B N   1 
ATOM 735  C CA  . LYS B 1 242 ? 137.647 152.348 142.825 1.00 31.44 ? 331 LYS B CA  1 
ATOM 736  C C   . LYS B 1 242 ? 138.035 151.038 143.540 1.00 31.44 ? 331 LYS B C   1 
ATOM 737  O O   . LYS B 1 242 ? 138.822 151.069 144.484 1.00 31.44 ? 331 LYS B O   1 
ATOM 738  C CB  . LYS B 1 242 ? 138.621 153.509 143.129 1.00 31.44 ? 331 LYS B CB  1 
ATOM 739  C CG  . LYS B 1 242 ? 138.484 154.717 142.192 1.00 31.44 ? 331 LYS B CG  1 
ATOM 740  C CD  . LYS B 1 242 ? 139.197 155.970 142.710 1.00 31.44 ? 331 LYS B CD  1 
ATOM 741  C CE  . LYS B 1 242 ? 140.721 155.810 142.739 1.00 31.44 ? 331 LYS B CE  1 
ATOM 742  N NZ  . LYS B 1 242 ? 141.374 157.078 143.145 1.00 31.44 ? 331 LYS B NZ  1 
ATOM 743  N N   . PRO B 1 243 ? 137.474 149.878 143.141 1.00 31.12 ? 332 PRO B N   1 
ATOM 744  C CA  . PRO B 1 243 ? 137.774 148.588 143.772 1.00 31.12 ? 332 PRO B CA  1 
ATOM 745  C C   . PRO B 1 243 ? 139.168 148.035 143.448 1.00 31.12 ? 332 PRO B C   1 
ATOM 746  O O   . PRO B 1 243 ? 139.628 148.101 142.312 1.00 31.12 ? 332 PRO B O   1 
ATOM 747  C CB  . PRO B 1 243 ? 136.694 147.615 143.287 1.00 31.12 ? 332 PRO B CB  1 
ATOM 748  C CG  . PRO B 1 243 ? 135.588 148.523 142.779 1.00 31.12 ? 332 PRO B CG  1 
ATOM 749  C CD  . PRO B 1 243 ? 136.340 149.726 142.249 1.00 31.12 ? 332 PRO B CD  1 
ATOM 750  N N   . GLY B 1 244 ? 139.819 147.407 144.423 1.00 30.86 ? 333 GLY B N   1 
ATOM 751  C CA  . GLY B 1 244 ? 141.202 146.916 144.343 1.00 30.86 ? 333 GLY B CA  1 
ATOM 752  C C   . GLY B 1 244 ? 141.383 145.423 144.061 1.00 30.86 ? 333 GLY B C   1 
ATOM 753  O O   . GLY B 1 244 ? 142.230 144.793 144.682 1.00 30.86 ? 333 GLY B O   1 
ATOM 754  N N   . GLY B 1 245 ? 140.608 144.831 143.156 1.00 30.37 ? 334 GLY B N   1 
ATOM 755  C CA  . GLY B 1 245 ? 140.744 143.423 142.753 1.00 30.37 ? 334 GLY B CA  1 
ATOM 756  C C   . GLY B 1 245 ? 140.286 142.413 143.810 1.00 30.37 ? 334 GLY B C   1 
ATOM 757  O O   . GLY B 1 245 ? 139.304 142.649 144.511 1.00 30.37 ? 334 GLY B O   1 
ATOM 758  N N   . GLY B 1 246 ? 140.981 141.282 143.932 1.00 30.75 ? 335 GLY B N   1 
ATOM 759  C CA  . GLY B 1 246 ? 140.644 140.195 144.861 1.00 30.75 ? 335 GLY B CA  1 
ATOM 760  C C   . GLY B 1 246 ? 140.652 138.810 144.220 1.00 30.75 ? 335 GLY B C   1 
ATOM 761  O O   . GLY B 1 246 ? 140.905 138.665 143.025 1.00 30.75 ? 335 GLY B O   1 
ATOM 762  N N   . GLN B 1 247 ? 140.377 137.773 145.007 1.00 31.95 ? 336 GLN B N   1 
ATOM 763  C CA  . GLN B 1 247 ? 140.421 136.384 144.547 1.00 31.95 ? 336 GLN B CA  1 
ATOM 764  C C   . GLN B 1 247 ? 139.305 135.517 145.146 1.00 31.95 ? 336 GLN B C   1 
ATOM 765  O O   . GLN B 1 247 ? 139.042 135.583 146.345 1.00 31.95 ? 336 GLN B O   1 
ATOM 766  C CB  . GLN B 1 247 ? 141.825 135.846 144.849 1.00 31.95 ? 336 GLN B CB  1 
ATOM 767  C CG  . GLN B 1 247 ? 142.129 134.506 144.177 1.00 31.95 ? 336 GLN B CG  1 
ATOM 768  C CD  . GLN B 1 247 ? 143.631 134.298 144.112 1.00 31.95 ? 336 GLN B CD  1 
ATOM 769  O OE1 . GLN B 1 247 ? 144.259 133.859 145.060 1.00 31.95 ? 336 GLN B OE1 1 
ATOM 770  N NE2 . GLN B 1 247 ? 144.268 134.618 143.015 1.00 31.95 ? 336 GLN B NE2 1 
ATOM 771  N N   . VAL B 1 248 ? 138.664 134.677 144.329 1.00 34.06 ? 337 VAL B N   1 
ATOM 772  C CA  . VAL B 1 248 ? 137.558 133.785 144.730 1.00 34.06 ? 337 VAL B CA  1 
ATOM 773  C C   . VAL B 1 248 ? 137.787 132.377 144.183 1.00 34.06 ? 337 VAL B C   1 
ATOM 774  O O   . VAL B 1 248 ? 138.089 132.215 143.007 1.00 34.06 ? 337 VAL B O   1 
ATOM 775  C CB  . VAL B 1 248 ? 136.194 134.338 144.250 1.00 34.06 ? 337 VAL B CB  1 
ATOM 776  C CG1 . VAL B 1 248 ? 135.019 133.438 144.646 1.00 34.06 ? 337 VAL B CG1 1 
ATOM 777  C CG2 . VAL B 1 248 ? 135.899 135.728 144.815 1.00 34.06 ? 337 VAL B CG2 1 
ATOM 778  N N   . GLU B 1 249 ? 137.590 131.351 145.005 1.00 37.66 ? 338 GLU B N   1 
ATOM 779  C CA  . GLU B 1 249 ? 137.641 129.939 144.614 1.00 37.66 ? 338 GLU B CA  1 
ATOM 780  C C   . GLU B 1 249 ? 136.452 129.164 145.189 1.00 37.66 ? 338 GLU B C   1 
ATOM 781  O O   . GLU B 1 249 ? 136.178 129.257 146.385 1.00 37.66 ? 338 GLU B O   1 
ATOM 782  C CB  . GLU B 1 249 ? 138.974 129.329 145.069 1.00 37.66 ? 338 GLU B CB  1 
ATOM 783  C CG  . GLU B 1 249 ? 139.096 127.834 144.735 1.00 37.66 ? 338 GLU B CG  1 
ATOM 784  C CD  . GLU B 1 249 ? 140.465 127.228 145.087 1.00 37.66 ? 338 GLU B CD  1 
ATOM 785  O OE1 . GLU B 1 249 ? 141.459 127.969 145.258 1.00 37.66 ? 338 GLU B OE1 1 
ATOM 786  O OE2 . GLU B 1 249 ? 140.554 125.985 145.206 1.00 37.66 ? 338 GLU B OE2 1 
ATOM 787  N N   . VAL B 1 250 ? 135.778 128.352 144.373 1.00 39.59 ? 339 VAL B N   1 
ATOM 788  C CA  . VAL B 1 250 ? 134.674 127.483 144.815 1.00 39.59 ? 339 VAL B CA  1 
ATOM 789  C C   . VAL B 1 250 ? 134.837 126.072 144.246 1.00 39.59 ? 339 VAL B C   1 
ATOM 790  O O   . VAL B 1 250 ? 135.150 125.899 143.072 1.00 39.59 ? 339 VAL B O   1 
ATOM 791  C CB  . VAL B 1 250 ? 133.294 128.074 144.458 1.00 39.59 ? 339 VAL B CB  1 
ATOM 792  C CG1 . VAL B 1 250 ? 132.168 127.227 145.055 1.00 39.59 ? 339 VAL B CG1 1 
ATOM 793  C CG2 . VAL B 1 250 ? 133.111 129.509 144.960 1.00 39.59 ? 339 VAL B CG2 1 
ATOM 794  N N   . LYS B 1 251 ? 134.592 125.052 145.067 1.00 44.07 ? 340 LYS B N   1 
ATOM 795  C CA  . LYS B 1 251 ? 134.669 123.632 144.707 1.00 44.07 ? 340 LYS B CA  1 
ATOM 796  C C   . LYS B 1 251 ? 133.388 122.908 145.125 1.00 44.07 ? 340 LYS B C   1 
ATOM 797  O O   . LYS B 1 251 ? 132.925 123.077 146.251 1.00 44.07 ? 340 LYS B O   1 
ATOM 798  C CB  . LYS B 1 251 ? 135.912 123.038 145.380 1.00 44.07 ? 340 LYS B CB  1 
ATOM 799  C CG  . LYS B 1 251 ? 136.202 121.589 144.962 1.00 44.07 ? 340 LYS B CG  1 
ATOM 800  C CD  . LYS B 1 251 ? 137.471 121.041 145.632 1.00 44.07 ? 340 LYS B CD  1 
ATOM 801  C CE  . LYS B 1 251 ? 138.752 121.770 145.203 1.00 44.07 ? 340 LYS B CE  1 
ATOM 802  N NZ  . LYS B 1 251 ? 139.955 121.149 145.798 1.00 44.07 ? 340 LYS B NZ  1 
ATOM 803  N N   . SER B 1 252 ? 132.842 122.079 144.241 1.00 48.72 ? 341 SER B N   1 
ATOM 804  C CA  . SER B 1 252 ? 131.612 121.295 144.436 1.00 48.72 ? 341 SER B CA  1 
ATOM 805  C C   . SER B 1 252 ? 131.742 119.909 143.801 1.00 48.72 ? 341 SER B C   1 
ATOM 806  O O   . SER B 1 252 ? 132.501 119.723 142.853 1.00 48.72 ? 341 SER B O   1 
ATOM 807  C CB  . SER B 1 252 ? 130.418 122.002 143.780 1.00 48.72 ? 341 SER B CB  1 
ATOM 808  O OG  . SER B 1 252 ? 130.135 123.233 144.413 1.00 48.72 ? 341 SER B OG  1 
ATOM 809  N N   . GLU B 1 253 ? 130.979 118.928 144.279 1.00 51.37 ? 342 GLU B N   1 
ATOM 810  C CA  . GLU B 1 253 ? 130.845 117.645 143.570 1.00 51.37 ? 342 GLU B CA  1 
ATOM 811  C C   . GLU B 1 253 ? 129.635 117.675 142.625 1.00 51.37 ? 342 GLU B C   1 
ATOM 812  O O   . GLU B 1 253 ? 129.787 117.568 141.413 1.00 51.37 ? 342 GLU B O   1 
ATOM 813  C CB  . GLU B 1 253 ? 130.690 116.490 144.575 1.00 51.37 ? 342 GLU B CB  1 
ATOM 814  C CG  . GLU B 1 253 ? 131.793 116.375 145.639 1.00 51.37 ? 342 GLU B CG  1 
ATOM 815  C CD  . GLU B 1 253 ? 133.188 116.017 145.102 1.00 51.37 ? 342 GLU B CD  1 
ATOM 816  O OE1 . GLU B 1 253 ? 133.297 115.353 144.049 1.00 51.37 ? 342 GLU B OE1 1 
ATOM 817  O OE2 . GLU B 1 253 ? 134.191 116.368 145.764 1.00 51.37 ? 342 GLU B OE2 1 
ATOM 818  N N   . LYS B 1 254 ? 128.437 117.951 143.144 1.00 50.94 ? 343 LYS B N   1 
ATOM 819  C CA  . LYS B 1 254 ? 127.174 117.899 142.393 1.00 50.94 ? 343 LYS B CA  1 
ATOM 820  C C   . LYS B 1 254 ? 126.277 119.068 142.775 1.00 50.94 ? 343 LYS B C   1 
ATOM 821  O O   . LYS B 1 254 ? 126.159 119.374 143.958 1.00 50.94 ? 343 LYS B O   1 
ATOM 822  C CB  . LYS B 1 254 ? 126.444 116.578 142.699 1.00 50.94 ? 343 LYS B CB  1 
ATOM 823  C CG  . LYS B 1 254 ? 127.221 115.323 142.291 1.00 50.94 ? 343 LYS B CG  1 
ATOM 824  C CD  . LYS B 1 254 ? 126.339 114.082 142.434 1.00 50.94 ? 343 LYS B CD  1 
ATOM 825  C CE  . LYS B 1 254 ? 127.096 112.816 142.030 1.00 50.94 ? 343 LYS B CE  1 
ATOM 826  N NZ  . LYS B 1 254 ? 126.226 111.623 142.087 1.00 50.94 ? 343 LYS B NZ  1 
ATOM 827  N N   . LEU B 1 255 ? 125.634 119.706 141.802 1.00 50.12 ? 344 LEU B N   1 
ATOM 828  C CA  . LEU B 1 255 ? 124.564 120.681 142.025 1.00 50.12 ? 344 LEU B CA  1 
ATOM 829  C C   . LEU B 1 255 ? 123.280 120.213 141.345 1.00 50.12 ? 344 LEU B C   1 
ATOM 830  O O   . LEU B 1 255 ? 123.298 119.776 140.198 1.00 50.12 ? 344 LEU B O   1 
ATOM 831  C CB  . LEU B 1 255 ? 124.971 122.094 141.568 1.00 50.12 ? 344 LEU B CB  1 
ATOM 832  C CG  . LEU B 1 255 ? 126.258 122.666 142.189 1.00 50.12 ? 344 LEU B CG  1 
ATOM 833  C CD1 . LEU B 1 255 ? 126.543 124.054 141.628 1.00 50.12 ? 344 LEU B CD1 1 
ATOM 834  C CD2 . LEU B 1 255 ? 126.131 122.852 143.701 1.00 50.12 ? 344 LEU B CD2 1 
ATOM 835  N N   . ASP B 1 256 ? 122.165 120.299 142.061 1.00 49.93 ? 345 ASP B N   1 
ATOM 836  C CA  . ASP B 1 256 ? 120.889 119.686 141.691 1.00 49.93 ? 345 ASP B CA  1 
ATOM 837  C C   . ASP B 1 256 ? 119.735 120.599 142.121 1.00 49.93 ? 345 ASP B C   1 
ATOM 838  O O   . ASP B 1 256 ? 119.352 120.618 143.289 1.00 49.93 ? 345 ASP B O   1 
ATOM 839  C CB  . ASP B 1 256 ? 120.862 118.293 142.343 1.00 49.93 ? 345 ASP B CB  1 
ATOM 840  C CG  . ASP B 1 256 ? 119.645 117.434 141.995 1.00 49.93 ? 345 ASP B CG  1 
ATOM 841  O OD1 . ASP B 1 256 ? 118.742 117.895 141.268 1.00 49.93 ? 345 ASP B OD1 1 
ATOM 842  O OD2 . ASP B 1 256 ? 119.606 116.269 142.448 1.00 49.93 ? 345 ASP B OD2 1 
ATOM 843  N N   . PHE B 1 257 ? 119.241 121.426 141.200 1.00 48.05 ? 346 PHE B N   1 
ATOM 844  C CA  . PHE B 1 257 ? 118.285 122.507 141.462 1.00 48.05 ? 346 PHE B CA  1 
ATOM 845  C C   . PHE B 1 257 ? 116.933 122.228 140.802 1.00 48.05 ? 346 PHE B C   1 
ATOM 846  O O   . PHE B 1 257 ? 116.879 121.975 139.602 1.00 48.05 ? 346 PHE B O   1 
ATOM 847  C CB  . PHE B 1 257 ? 118.838 123.860 140.974 1.00 48.05 ? 346 PHE B CB  1 
ATOM 848  C CG  . PHE B 1 257 ? 120.161 124.364 141.535 1.00 48.05 ? 346 PHE B CG  1 
ATOM 849  C CD1 . PHE B 1 257 ? 120.740 123.827 142.701 1.00 48.05 ? 346 PHE B CD1 1 
ATOM 850  C CD2 . PHE B 1 257 ? 120.817 125.419 140.875 1.00 48.05 ? 346 PHE B CD2 1 
ATOM 851  C CE1 . PHE B 1 257 ? 121.985 124.285 143.156 1.00 48.05 ? 346 PHE B CE1 1 
ATOM 852  C CE2 . PHE B 1 257 ? 122.057 125.889 141.337 1.00 48.05 ? 346 PHE B CE2 1 
ATOM 853  C CZ  . PHE B 1 257 ? 122.647 125.312 142.471 1.00 48.05 ? 346 PHE B CZ  1 
ATOM 854  N N   . LYS B 1 258 ? 115.836 122.328 141.562 1.00 48.31 ? 347 LYS B N   1 
ATOM 855  C CA  . LYS B 1 258 ? 114.460 122.118 141.081 1.00 48.31 ? 347 LYS B CA  1 
ATOM 856  C C   . LYS B 1 258 ? 113.524 123.234 141.534 1.00 48.31 ? 347 LYS B C   1 
ATOM 857  O O   . LYS B 1 258 ? 113.598 123.633 142.691 1.00 48.31 ? 347 LYS B O   1 
ATOM 858  C CB  . LYS B 1 258 ? 113.901 120.781 141.598 1.00 48.31 ? 347 LYS B CB  1 
ATOM 859  C CG  . LYS B 1 258 ? 114.735 119.558 141.205 1.00 48.31 ? 347 LYS B CG  1 
ATOM 860  C CD  . LYS B 1 258 ? 114.053 118.270 141.677 1.00 48.31 ? 347 LYS B CD  1 
ATOM 861  C CE  . LYS B 1 258 ? 114.943 117.059 141.378 1.00 48.31 ? 347 LYS B CE  1 
ATOM 862  N NZ  . LYS B 1 258 ? 114.250 115.784 141.681 1.00 48.31 ? 347 LYS B NZ  1 
ATOM 863  N N   . ASP B 1 259 ? 112.568 123.625 140.697 1.00 45.92 ? 348 ASP B N   1 
ATOM 864  C CA  . ASP B 1 259 ? 111.363 124.383 141.076 1.00 45.92 ? 348 ASP B CA  1 
ATOM 865  C C   . ASP B 1 259 ? 111.633 125.739 141.758 1.00 45.92 ? 348 ASP B C   1 
ATOM 866  O O   . ASP B 1 259 ? 111.681 125.833 142.984 1.00 45.92 ? 348 ASP B O   1 
ATOM 867  C CB  . ASP B 1 259 ? 110.433 123.479 141.903 1.00 45.92 ? 348 ASP B CB  1 
ATOM 868  C CG  . ASP B 1 259 ? 109.122 124.162 142.305 1.00 45.92 ? 348 ASP B CG  1 
ATOM 869  O OD1 . ASP B 1 259 ? 108.703 125.150 141.667 1.00 45.92 ? 348 ASP B OD1 1 
ATOM 870  O OD2 . ASP B 1 259 ? 108.478 123.713 143.277 1.00 45.92 ? 348 ASP B OD2 1 
ATOM 871  N N   . ARG B 1 260 ? 111.753 126.809 140.961 1.00 44.03 ? 349 ARG B N   1 
ATOM 872  C CA  . ARG B 1 260 ? 111.923 128.207 141.423 1.00 44.03 ? 349 ARG B CA  1 
ATOM 873  C C   . ARG B 1 260 ? 113.181 128.420 142.275 1.00 44.03 ? 349 ARG B C   1 
ATOM 874  O O   . ARG B 1 260 ? 113.109 128.883 143.409 1.00 44.03 ? 349 ARG B O   1 
ATOM 875  C CB  . ARG B 1 260 ? 110.639 128.729 142.105 1.00 44.03 ? 349 ARG B CB  1 
ATOM 876  C CG  . ARG B 1 260 ? 109.442 128.838 141.155 1.00 44.03 ? 349 ARG B CG  1 
ATOM 877  C CD  . ARG B 1 260 ? 108.122 128.913 141.929 1.00 44.03 ? 349 ARG B CD  1 
ATOM 878  N NE  . ARG B 1 260 ? 107.801 127.606 142.533 1.00 44.03 ? 349 ARG B NE  1 
ATOM 879  C CZ  . ARG B 1 260 ? 107.133 127.356 143.641 1.00 44.03 ? 349 ARG B CZ  1 
ATOM 880  N NH1 . ARG B 1 260 ? 106.499 128.281 144.298 1.00 44.03 ? 349 ARG B NH1 1 
ATOM 881  N NH2 . ARG B 1 260 ? 107.079 126.144 144.101 1.00 44.03 ? 349 ARG B NH2 1 
ATOM 882  N N   . VAL B 1 261 ? 114.349 128.104 141.717 1.00 42.60 ? 350 VAL B N   1 
ATOM 883  C CA  . VAL B 1 261 ? 115.660 128.368 142.337 1.00 42.60 ? 350 VAL B CA  1 
ATOM 884  C C   . VAL B 1 261 ? 116.331 129.562 141.670 1.00 42.60 ? 350 VAL B C   1 
ATOM 885  O O   . VAL B 1 261 ? 116.484 129.581 140.455 1.00 42.60 ? 350 VAL B O   1 
ATOM 886  C CB  . VAL B 1 261 ? 116.574 127.130 142.278 1.00 42.60 ? 350 VAL B CB  1 
ATOM 887  C CG1 . VAL B 1 261 ? 117.983 127.403 142.815 1.00 42.60 ? 350 VAL B CG1 1 
ATOM 888  C CG2 . VAL B 1 261 ? 115.978 125.991 143.099 1.00 42.60 ? 350 VAL B CG2 1 
ATOM 889  N N   . GLN B 1 262 ? 116.791 130.530 142.459 1.00 39.71 ? 351 GLN B N   1 
ATOM 890  C CA  . GLN B 1 262 ? 117.678 131.604 142.011 1.00 39.71 ? 351 GLN B CA  1 
ATOM 891  C C   . GLN B 1 262 ? 119.043 131.458 142.702 1.00 39.71 ? 351 GLN B C   1 
ATOM 892  O O   . GLN B 1 262 ? 119.118 131.489 143.926 1.00 39.71 ? 351 GLN B O   1 
ATOM 893  C CB  . GLN B 1 262 ? 116.997 132.948 142.282 1.00 39.71 ? 351 GLN B CB  1 
ATOM 894  C CG  . GLN B 1 262 ? 117.843 134.143 141.824 1.00 39.71 ? 351 GLN B CG  1 
ATOM 895  C CD  . GLN B 1 262 ? 117.188 135.494 142.100 1.00 39.71 ? 351 GLN B CD  1 
ATOM 896  O OE1 . GLN B 1 262 ? 117.850 136.471 142.425 1.00 39.71 ? 351 GLN B OE1 1 
ATOM 897  N NE2 . GLN B 1 262 ? 115.882 135.617 142.015 1.00 39.71 ? 351 GLN B NE2 1 
ATOM 898  N N   . SER B 1 263 ? 120.120 131.281 141.938 1.00 38.51 ? 352 SER B N   1 
ATOM 899  C CA  . SER B 1 263 ? 121.440 130.904 142.462 1.00 38.51 ? 352 SER B CA  1 
ATOM 900  C C   . SER B 1 263 ? 122.585 131.719 141.858 1.00 38.51 ? 352 SER B C   1 
ATOM 901  O O   . SER B 1 263 ? 122.587 132.014 140.664 1.00 38.51 ? 352 SER B O   1 
ATOM 902  C CB  . SER B 1 263 ? 121.645 129.406 142.244 1.00 38.51 ? 352 SER B CB  1 
ATOM 903  O OG  . SER B 1 263 ? 122.859 128.992 142.826 1.00 38.51 ? 352 SER B OG  1 
ATOM 904  N N   . LYS B 1 264 ? 123.578 132.071 142.678 1.00 36.97 ? 353 LYS B N   1 
ATOM 905  C CA  . LYS B 1 264 ? 124.822 132.744 142.282 1.00 36.97 ? 353 LYS B CA  1 
ATOM 906  C C   . LYS B 1 264 ? 126.012 132.078 142.974 1.00 36.97 ? 353 LYS B C   1 
ATOM 907  O O   . LYS B 1 264 ? 126.058 132.056 144.200 1.00 36.97 ? 353 LYS B O   1 
ATOM 908  C CB  . LYS B 1 264 ? 124.668 134.237 142.610 1.00 36.97 ? 353 LYS B CB  1 
ATOM 909  C CG  . LYS B 1 264 ? 125.777 135.118 142.035 1.00 36.97 ? 353 LYS B CG  1 
ATOM 910  C CD  . LYS B 1 264 ? 125.544 136.574 142.463 1.00 36.97 ? 353 LYS B CD  1 
ATOM 911  C CE  . LYS B 1 264 ? 126.561 137.508 141.804 1.00 36.97 ? 353 LYS B CE  1 
ATOM 912  N NZ  . LYS B 1 264 ? 126.467 138.887 142.338 1.00 36.97 ? 353 LYS B NZ  1 
ATOM 913  N N   . ILE B 1 265 ? 126.953 131.514 142.217 1.00 37.68 ? 354 ILE B N   1 
ATOM 914  C CA  . ILE B 1 265 ? 128.121 130.773 142.729 1.00 37.68 ? 354 ILE B CA  1 
ATOM 915  C C   . ILE B 1 265 ? 129.421 131.320 142.136 1.00 37.68 ? 354 ILE B C   1 
ATOM 916  O O   . ILE B 1 265 ? 129.600 131.308 140.925 1.00 37.68 ? 354 ILE B O   1 
ATOM 917  C CB  . ILE B 1 265 ? 127.964 129.252 142.479 1.00 37.68 ? 354 ILE B CB  1 
ATOM 918  C CG1 . ILE B 1 265 ? 126.688 128.711 143.164 1.00 37.68 ? 354 ILE B CG1 1 
ATOM 919  C CG2 . ILE B 1 265 ? 129.201 128.473 142.957 1.00 37.68 ? 354 ILE B CG2 1 
ATOM 920  C CD1 . ILE B 1 265 ? 126.413 127.229 142.927 1.00 37.68 ? 354 ILE B CD1 1 
ATOM 921  N N   . GLY B 1 266 ? 130.352 131.754 142.986 1.00 36.70 ? 355 GLY B N   1 
ATOM 922  C CA  . GLY B 1 266 ? 131.680 132.228 142.588 1.00 36.70 ? 355 GLY B CA  1 
ATOM 923  C C   . GLY B 1 266 ? 131.650 133.507 141.749 1.00 36.70 ? 355 GLY B C   1 
ATOM 924  O O   . GLY B 1 266 ? 131.714 133.454 140.528 1.00 36.70 ? 355 GLY B O   1 
ATOM 925  N N   . SER B 1 267 ? 131.575 134.672 142.381 1.00 35.60 ? 356 SER B N   1 
ATOM 926  C CA  . SER B 1 267 ? 131.552 135.961 141.679 1.00 35.60 ? 356 SER B CA  1 
ATOM 927  C C   . SER B 1 267 ? 132.473 137.017 142.275 1.00 35.60 ? 356 SER B C   1 
ATOM 928  O O   . SER B 1 267 ? 132.648 137.063 143.489 1.00 35.60 ? 356 SER B O   1 
ATOM 929  C CB  . SER B 1 267 ? 130.123 136.486 141.607 1.00 35.60 ? 356 SER B CB  1 
ATOM 930  O OG  . SER B 1 267 ? 129.654 136.836 142.897 1.00 35.60 ? 356 SER B OG  1 
ATOM 931  N N   . LEU B 1 268 ? 132.941 137.945 141.441 1.00 34.82 ? 357 LEU B N   1 
ATOM 932  C CA  . LEU B 1 268 ? 133.680 139.146 141.836 1.00 34.82 ? 357 LEU B CA  1 
ATOM 933  C C   . LEU B 1 268 ? 133.103 140.329 141.039 1.00 34.82 ? 357 LEU B C   1 
ATOM 934  O O   . LEU B 1 268 ? 133.670 140.788 140.054 1.00 34.82 ? 357 LEU B O   1 
ATOM 935  C CB  . LEU B 1 268 ? 135.184 138.863 141.631 1.00 34.82 ? 357 LEU B CB  1 
ATOM 936  C CG  . LEU B 1 268 ? 136.167 139.797 142.364 1.00 34.82 ? 357 LEU B CG  1 
ATOM 937  C CD1 . LEU B 1 268 ? 137.540 139.135 142.422 1.00 34.82 ? 357 LEU B CD1 1 
ATOM 938  C CD2 . LEU B 1 268 ? 136.357 141.158 141.705 1.00 34.82 ? 357 LEU B CD2 1 
ATOM 939  N N   . ASP B 1 269 ? 131.915 140.779 141.451 1.00 35.60 ? 358 ASP B N   1 
ATOM 940  C CA  . ASP B 1 269 ? 131.077 141.724 140.700 1.00 35.60 ? 358 ASP B CA  1 
ATOM 941  C C   . ASP B 1 269 ? 131.033 143.123 141.351 1.00 35.60 ? 358 ASP B C   1 
ATOM 942  O O   . ASP B 1 269 ? 130.849 143.231 142.559 1.00 35.60 ? 358 ASP B O   1 
ATOM 943  C CB  . ASP B 1 269 ? 129.656 141.158 140.522 1.00 35.60 ? 358 ASP B CB  1 
ATOM 944  C CG  . ASP B 1 269 ? 129.518 139.843 139.726 1.00 35.60 ? 358 ASP B CG  1 
ATOM 945  O OD1 . ASP B 1 269 ? 130.461 139.385 139.045 1.00 35.60 ? 358 ASP B OD1 1 
ATOM 946  O OD2 . ASP B 1 269 ? 128.400 139.275 139.751 1.00 35.60 ? 358 ASP B OD2 1 
ATOM 947  N N   . ASN B 1 270 ? 131.197 144.200 140.577 1.00 32.99 ? 359 ASN B N   1 
ATOM 948  C CA  . ASN B 1 270 ? 131.181 145.601 141.042 1.00 32.99 ? 359 ASN B CA  1 
ATOM 949  C C   . ASN B 1 270 ? 130.023 146.407 140.436 1.00 32.99 ? 359 ASN B C   1 
ATOM 950  O O   . ASN B 1 270 ? 129.839 146.393 139.224 1.00 32.99 ? 359 ASN B O   1 
ATOM 951  C CB  . ASN B 1 270 ? 132.519 146.284 140.718 1.00 32.99 ? 359 ASN B CB  1 
ATOM 952  C CG  . ASN B 1 270 ? 133.721 145.572 141.297 1.00 32.99 ? 359 ASN B CG  1 
ATOM 953  O OD1 . ASN B 1 270 ? 133.915 145.513 142.497 1.00 32.99 ? 359 ASN B OD1 1 
ATOM 954  N ND2 . ASN B 1 270 ? 134.547 144.984 140.470 1.00 32.99 ? 359 ASN B ND2 1 
ATOM 955  N N   . ILE B 1 271 ? 129.268 147.161 141.237 1.00 31.23 ? 360 ILE B N   1 
ATOM 956  C CA  . ILE B 1 271 ? 128.113 147.951 140.772 1.00 31.23 ? 360 ILE B CA  1 
ATOM 957  C C   . ILE B 1 271 ? 128.259 149.402 141.230 1.00 31.23 ? 360 ILE B C   1 
ATOM 958  O O   . ILE B 1 271 ? 128.480 149.653 142.407 1.00 31.23 ? 360 ILE B O   1 
ATOM 959  C CB  . ILE B 1 271 ? 126.777 147.343 141.273 1.00 31.23 ? 360 ILE B CB  1 
ATOM 960  C CG1 . ILE B 1 271 ? 126.604 145.885 140.795 1.00 31.23 ? 360 ILE B CG1 1 
ATOM 961  C CG2 . ILE B 1 271 ? 125.586 148.197 140.800 1.00 31.23 ? 360 ILE B CG2 1 
ATOM 962  C CD1 . ILE B 1 271 ? 125.403 145.159 141.406 1.00 31.23 ? 360 ILE B CD1 1 
ATOM 963  N N   . THR B 1 272 ? 128.081 150.366 140.329 1.00 32.74 ? 361 THR B N   1 
ATOM 964  C CA  . THR B 1 272 ? 127.869 151.781 140.678 1.00 32.74 ? 361 THR B CA  1 
ATOM 965  C C   . THR B 1 272 ? 126.487 152.189 140.194 1.00 32.74 ? 361 THR B C   1 
ATOM 966  O O   . THR B 1 272 ? 126.234 152.151 138.995 1.00 32.74 ? 361 THR B O   1 
ATOM 967  C CB  . THR B 1 272 ? 128.929 152.679 140.028 1.00 32.74 ? 361 THR B CB  1 
ATOM 968  O OG1 . THR B 1 272 ? 130.210 152.250 140.405 1.00 32.74 ? 361 THR B OG1 1 
ATOM 969  C CG2 . THR B 1 272 ? 128.819 154.133 140.463 1.00 32.74 ? 361 THR B CG2 1 
ATOM 970  N N   . HIS B 1 273 ? 125.592 152.582 141.094 1.00 34.42 ? 362 HIS B N   1 
ATOM 971  C CA  . HIS B 1 273 ? 124.198 152.905 140.775 1.00 34.42 ? 362 HIS B CA  1 
ATOM 972  C C   . HIS B 1 273 ? 123.820 154.291 141.294 1.00 34.42 ? 362 HIS B C   1 
ATOM 973  O O   . HIS B 1 273 ? 123.833 154.520 142.499 1.00 34.42 ? 362 HIS B O   1 
ATOM 974  C CB  . HIS B 1 273 ? 123.302 151.781 141.313 1.00 34.42 ? 362 HIS B CB  1 
ATOM 975  C CG  . HIS B 1 273 ? 121.847 151.920 140.962 1.00 34.42 ? 362 HIS B CG  1 
ATOM 976  N ND1 . HIS B 1 273 ? 121.341 152.515 139.810 1.00 34.42 ? 362 HIS B ND1 1 
ATOM 977  C CD2 . HIS B 1 273 ? 120.815 151.377 141.659 1.00 34.42 ? 362 HIS B CD2 1 
ATOM 978  C CE1 . HIS B 1 273 ? 120.015 152.338 139.849 1.00 34.42 ? 362 HIS B CE1 1 
ATOM 979  N NE2 . HIS B 1 273 ? 119.673 151.655 140.947 1.00 34.42 ? 362 HIS B NE2 1 
ATOM 980  N N   . VAL B 1 274 ? 123.495 155.224 140.403 1.00 35.84 ? 363 VAL B N   1 
ATOM 981  C CA  . VAL B 1 274 ? 123.278 156.639 140.745 1.00 35.84 ? 363 VAL B CA  1 
ATOM 982  C C   . VAL B 1 274 ? 122.020 157.160 140.039 1.00 35.84 ? 363 VAL B C   1 
ATOM 983  O O   . VAL B 1 274 ? 122.121 157.889 139.057 1.00 35.84 ? 363 VAL B O   1 
ATOM 984  C CB  . VAL B 1 274 ? 124.529 157.509 140.462 1.00 35.84 ? 363 VAL B CB  1 
ATOM 985  C CG1 . VAL B 1 274 ? 124.366 158.915 141.051 1.00 35.84 ? 363 VAL B CG1 1 
ATOM 986  C CG2 . VAL B 1 274 ? 125.829 156.947 141.052 1.00 35.84 ? 363 VAL B CG2 1 
ATOM 987  N N   . PRO B 1 275 ? 120.810 156.764 140.468 1.00 37.93 ? 364 PRO B N   1 
ATOM 988  C CA  . PRO B 1 275 ? 119.583 157.273 139.871 1.00 37.93 ? 364 PRO B CA  1 
ATOM 989  C C   . PRO B 1 275 ? 119.318 158.728 140.281 1.00 37.93 ? 364 PRO B C   1 
ATOM 990  O O   . PRO B 1 275 ? 119.506 159.097 141.437 1.00 37.93 ? 364 PRO B O   1 
ATOM 991  C CB  . PRO B 1 275 ? 118.489 156.320 140.358 1.00 37.93 ? 364 PRO B CB  1 
ATOM 992  C CG  . PRO B 1 275 ? 119.002 155.848 141.716 1.00 37.93 ? 364 PRO B CG  1 
ATOM 993  C CD  . PRO B 1 275 ? 120.515 155.813 141.526 1.00 37.93 ? 364 PRO B CD  1 
ATOM 994  N N   . GLY B 1 276 ? 118.823 159.554 139.360 1.00 41.42 ? 365 GLY B N   1 
ATOM 995  C CA  . GLY B 1 276 ? 118.448 160.941 139.658 1.00 41.42 ? 365 GLY B CA  1 
ATOM 996  C C   . GLY B 1 276 ? 117.233 161.061 140.585 1.00 41.42 ? 365 GLY B C   1 
ATOM 997  O O   . GLY B 1 276 ? 117.112 162.024 141.337 1.00 41.42 ? 365 GLY B O   1 
ATOM 998  N N   . GLY B 1 277 ? 116.352 160.064 140.571 1.00 43.68 ? 366 GLY B N   1 
ATOM 999  C CA  . GLY B 1 277 ? 115.203 159.922 141.451 1.00 43.68 ? 366 GLY B CA  1 
ATOM 1000 C C   . GLY B 1 277 ? 115.335 158.702 142.341 1.00 43.68 ? 366 GLY B C   1 
ATOM 1001 O O   . GLY B 1 277 ? 115.662 158.818 143.517 1.00 43.68 ? 366 GLY B O   1 
ATOM 1002 N N   . GLY B 1 278 ? 115.121 157.516 141.770 1.00 47.09 ? 367 GLY B N   1 
ATOM 1003 C CA  . GLY B 1 278 ? 115.314 156.237 142.459 1.00 47.09 ? 367 GLY B CA  1 
ATOM 1004 C C   . GLY B 1 278 ? 114.222 155.853 143.462 1.00 47.09 ? 367 GLY B C   1 
ATOM 1005 O O   . GLY B 1 278 ? 114.451 154.991 144.306 1.00 47.09 ? 367 GLY B O   1 
ATOM 1006 N N   . ASN B 1 279 ? 113.057 156.494 143.415 1.00 49.21 ? 368 ASN B N   1 
ATOM 1007 C CA  . ASN B 1 279 ? 111.907 156.180 144.262 1.00 49.21 ? 368 ASN B CA  1 
ATOM 1008 C C   . ASN B 1 279 ? 111.181 154.903 143.834 1.00 49.21 ? 368 ASN B C   1 
ATOM 1009 O O   . ASN B 1 279 ? 111.095 154.591 142.649 1.00 49.21 ? 368 ASN B O   1 
ATOM 1010 C CB  . ASN B 1 279 ? 110.958 157.383 144.298 1.00 49.21 ? 368 ASN B CB  1 
ATOM 1011 C CG  . ASN B 1 279 ? 111.629 158.597 144.899 1.00 49.21 ? 368 ASN B CG  1 
ATOM 1012 O OD1 . ASN B 1 279 ? 112.187 158.535 145.973 1.00 49.21 ? 368 ASN B OD1 1 
ATOM 1013 N ND2 . ASN B 1 279 ? 111.619 159.720 144.266 1.00 49.21 ? 368 ASN B ND2 1 
ATOM 1014 N N   . LYS B 1 280 ? 110.614 154.185 144.804 1.00 51.15 ? 369 LYS B N   1 
ATOM 1015 C CA  . LYS B 1 280 ? 109.930 152.900 144.622 1.00 51.15 ? 369 LYS B CA  1 
ATOM 1016 C C   . LYS B 1 280 ? 108.567 152.935 145.303 1.00 51.15 ? 369 LYS B C   1 
ATOM 1017 O O   . LYS B 1 280 ? 108.467 153.412 146.432 1.00 51.15 ? 369 LYS B O   1 
ATOM 1018 C CB  . LYS B 1 280 ? 110.786 151.767 145.216 1.00 51.15 ? 369 LYS B CB  1 
ATOM 1019 C CG  . LYS B 1 280 ? 112.166 151.623 144.559 1.00 51.15 ? 369 LYS B CG  1 
ATOM 1020 C CD  . LYS B 1 280 ? 113.026 150.543 145.223 1.00 51.15 ? 369 LYS B CD  1 
ATOM 1021 C CE  . LYS B 1 280 ? 112.456 149.131 145.073 1.00 51.15 ? 369 LYS B CE  1 
ATOM 1022 N NZ  . LYS B 1 280 ? 113.423 148.121 145.556 1.00 51.15 ? 369 LYS B NZ  1 
ATOM 1023 N N   . LYS B 1 281 ? 107.535 152.395 144.658 1.00 53.80 ? 370 LYS B N   1 
ATOM 1024 C CA  . LYS B 1 281 ? 106.221 152.115 145.254 1.00 53.80 ? 370 LYS B CA  1 
ATOM 1025 C C   . LYS B 1 281 ? 105.750 150.727 144.834 1.00 53.80 ? 370 LYS B C   1 
ATOM 1026 O O   . LYS B 1 281 ? 105.757 150.414 143.649 1.00 53.80 ? 370 LYS B O   1 
ATOM 1027 C CB  . LYS B 1 281 ? 105.262 153.250 144.870 1.00 53.80 ? 370 LYS B CB  1 
ATOM 1028 C CG  . LYS B 1 281 ? 103.821 153.053 145.359 1.00 53.80 ? 370 LYS B CG  1 
ATOM 1029 C CD  . LYS B 1 281 ? 102.998 154.321 145.091 1.00 53.80 ? 370 LYS B CD  1 
ATOM 1030 C CE  . LYS B 1 281 ? 101.485 154.075 145.102 1.00 53.80 ? 370 LYS B CE  1 
ATOM 1031 N NZ  . LYS B 1 281 ? 100.932 153.803 146.443 1.00 53.80 ? 370 LYS B NZ  1 
ATOM 1032 N N   . ILE B 1 282 ? 105.348 149.891 145.785 1.00 55.47 ? 371 ILE B N   1 
ATOM 1033 C CA  . ILE B 1 282 ? 104.918 148.510 145.533 1.00 55.47 ? 371 ILE B CA  1 
ATOM 1034 C C   . ILE B 1 282 ? 103.559 148.296 146.183 1.00 55.47 ? 371 ILE B C   1 
ATOM 1035 O O   . ILE B 1 282 ? 103.389 148.572 147.365 1.00 55.47 ? 371 ILE B O   1 
ATOM 1036 C CB  . ILE B 1 282 ? 105.968 147.494 146.046 1.00 55.47 ? 371 ILE B CB  1 
ATOM 1037 C CG1 . ILE B 1 282 ? 107.309 147.659 145.299 1.00 55.47 ? 371 ILE B CG1 1 
ATOM 1038 C CG2 . ILE B 1 282 ? 105.458 146.050 145.897 1.00 55.47 ? 371 ILE B CG2 1 
ATOM 1039 C CD1 . ILE B 1 282 ? 108.466 146.880 145.916 1.00 55.47 ? 371 ILE B CD1 1 
ATOM 1040 N N   . GLU B 1 283 ? 102.606 147.759 145.431 1.00 58.60 ? 372 GLU B N   1 
ATOM 1041 C CA  . GLU B 1 283 ? 101.239 147.470 145.870 1.00 58.60 ? 372 GLU B CA  1 
ATOM 1042 C C   . GLU B 1 283 ? 100.824 146.046 145.500 1.00 58.60 ? 372 GLU B C   1 
ATOM 1043 O O   . GLU B 1 283 ? 101.263 145.497 144.491 1.00 58.60 ? 372 GLU B O   1 
ATOM 1044 C CB  . GLU B 1 283 ? 100.247 148.452 145.238 1.00 58.60 ? 372 GLU B CB  1 
ATOM 1045 C CG  . GLU B 1 283 ? 100.554 149.939 145.472 1.00 58.60 ? 372 GLU B CG  1 
ATOM 1046 C CD  . GLU B 1 283 ? 100.385 150.371 146.933 1.00 58.60 ? 372 GLU B CD  1 
ATOM 1047 O OE1 . GLU B 1 283 ? 99.457  149.888 147.618 1.00 58.60 ? 372 GLU B OE1 1 
ATOM 1048 O OE2 . GLU B 1 283 ? 101.130 151.277 147.375 1.00 58.60 ? 372 GLU B OE2 1 
ATOM 1049 N N   . THR B 1 284 ? 99.946  145.430 146.286 1.00 61.89 ? 373 THR B N   1 
ATOM 1050 C CA  . THR B 1 284 ? 99.413  144.087 146.015 1.00 61.89 ? 373 THR B CA  1 
ATOM 1051 C C   . THR B 1 284 ? 98.027  143.954 146.632 1.00 61.89 ? 373 THR B C   1 
ATOM 1052 O O   . THR B 1 284 ? 97.868  144.143 147.835 1.00 61.89 ? 373 THR B O   1 
ATOM 1053 C CB  . THR B 1 284 ? 100.366 143.013 146.561 1.00 61.89 ? 373 THR B CB  1 
ATOM 1054 O OG1 . THR B 1 284 ? 101.491 142.933 145.718 1.00 61.89 ? 373 THR B OG1 1 
ATOM 1055 C CG2 . THR B 1 284 ? 99.776  141.606 146.597 1.00 61.89 ? 373 THR B CG2 1 
ATOM 1056 N N   . HIS B 1 285 ? 97.030  143.631 145.812 1.00 64.71 ? 374 HIS B N   1 
ATOM 1057 C CA  . HIS B 1 285 ? 95.626  143.437 146.186 1.00 64.71 ? 374 HIS B CA  1 
ATOM 1058 C C   . HIS B 1 285 ? 95.187  142.008 145.890 1.00 64.71 ? 374 HIS B C   1 
ATOM 1059 O O   . HIS B 1 285 ? 95.267  141.562 144.747 1.00 64.71 ? 374 HIS B O   1 
ATOM 1060 C CB  . HIS B 1 285 ? 94.754  144.413 145.386 1.00 64.71 ? 374 HIS B CB  1 
ATOM 1061 C CG  . HIS B 1 285 ? 94.994  145.869 145.686 1.00 64.71 ? 374 HIS B CG  1 
ATOM 1062 N ND1 . HIS B 1 285 ? 94.619  146.536 146.851 1.00 64.71 ? 374 HIS B ND1 1 
ATOM 1063 C CD2 . HIS B 1 285 ? 95.691  146.730 144.899 1.00 64.71 ? 374 HIS B CD2 1 
ATOM 1064 C CE1 . HIS B 1 285 ? 95.064  147.795 146.720 1.00 64.71 ? 374 HIS B CE1 1 
ATOM 1065 N NE2 . HIS B 1 285 ? 95.712  147.938 145.556 1.00 64.71 ? 374 HIS B NE2 1 
ATOM 1066 N N   . LYS B 1 286 ? 94.669  141.297 146.890 1.00 69.21 ? 375 LYS B N   1 
ATOM 1067 C CA  . LYS B 1 286 ? 94.312  139.877 146.776 1.00 69.21 ? 375 LYS B CA  1 
ATOM 1068 C C   . LYS B 1 286 ? 92.977  139.593 147.458 1.00 69.21 ? 375 LYS B C   1 
ATOM 1069 O O   . LYS B 1 286 ? 92.783  139.980 148.608 1.00 69.21 ? 375 LYS B O   1 
ATOM 1070 C CB  . LYS B 1 286 ? 95.457  139.076 147.412 1.00 69.21 ? 375 LYS B CB  1 
ATOM 1071 C CG  . LYS B 1 286 ? 95.357  137.558 147.220 1.00 69.21 ? 375 LYS B CG  1 
ATOM 1072 C CD  . LYS B 1 286 ? 96.658  136.868 147.656 1.00 69.21 ? 375 LYS B CD  1 
ATOM 1073 C CE  . LYS B 1 286 ? 97.829  137.118 146.693 1.00 69.21 ? 375 LYS B CE  1 
ATOM 1074 N NZ  . LYS B 1 286 ? 99.086  136.502 147.187 1.00 69.21 ? 375 LYS B NZ  1 
ATOM 1075 N N   . LEU B 1 287 ? 92.084  138.880 146.778 1.00 73.49 ? 376 LEU B N   1 
ATOM 1076 C CA  . LEU B 1 287 ? 90.803  138.413 147.321 1.00 73.49 ? 376 LEU B CA  1 
ATOM 1077 C C   . LEU B 1 287 ? 90.599  136.936 146.955 1.00 73.49 ? 376 LEU B C   1 
ATOM 1078 O O   . LEU B 1 287 ? 90.813  136.558 145.807 1.00 73.49 ? 376 LEU B O   1 
ATOM 1079 C CB  . LEU B 1 287 ? 89.694  139.361 146.822 1.00 73.49 ? 376 LEU B CB  1 
ATOM 1080 C CG  . LEU B 1 287 ? 88.258  138.966 147.205 1.00 73.49 ? 376 LEU B CG  1 
ATOM 1081 C CD1 . LEU B 1 287 ? 88.063  138.885 148.717 1.00 73.49 ? 376 LEU B CD1 1 
ATOM 1082 C CD2 . LEU B 1 287 ? 87.271  140.012 146.686 1.00 73.49 ? 376 LEU B CD2 1 
ATOM 1083 N N   . THR B 1 288 ? 90.230  136.073 147.904 1.00 77.93 ? 377 THR B N   1 
ATOM 1084 C CA  . THR B 1 288 ? 90.096  134.618 147.676 1.00 77.93 ? 377 THR B CA  1 
ATOM 1085 C C   . THR B 1 288 ? 88.859  134.035 148.363 1.00 77.93 ? 377 THR B C   1 
ATOM 1086 O O   . THR B 1 288 ? 88.566  134.378 149.507 1.00 77.93 ? 377 THR B O   1 
ATOM 1087 C CB  . THR B 1 288 ? 91.368  133.882 148.141 1.00 77.93 ? 377 THR B CB  1 
ATOM 1088 O OG1 . THR B 1 288 ? 92.475  134.319 147.391 1.00 77.93 ? 377 THR B OG1 1 
ATOM 1089 C CG2 . THR B 1 288 ? 91.322  132.366 147.957 1.00 77.93 ? 377 THR B CG2 1 
ATOM 1090 N N   . PHE B 1 289 ? 88.174  133.107 147.694 1.00 82.27 ? 378 PHE B N   1 
ATOM 1091 C CA  . PHE B 1 289 ? 87.026  132.355 148.215 1.00 82.27 ? 378 PHE B CA  1 
ATOM 1092 C C   . PHE B 1 289 ? 87.325  130.854 148.287 1.00 82.27 ? 378 PHE B C   1 
ATOM 1093 O O   . PHE B 1 289 ? 87.817  130.261 147.320 1.00 82.27 ? 378 PHE B O   1 
ATOM 1094 C CB  . PHE B 1 289 ? 85.796  132.633 147.348 1.00 82.27 ? 378 PHE B CB  1 
ATOM 1095 C CG  . PHE B 1 289 ? 85.339  134.074 147.392 1.00 82.27 ? 378 PHE B CG  1 
ATOM 1096 C CD1 . PHE B 1 289 ? 85.890  135.019 146.508 1.00 82.27 ? 378 PHE B CD1 1 
ATOM 1097 C CD2 . PHE B 1 289 ? 84.406  134.483 148.360 1.00 82.27 ? 378 PHE B CD2 1 
ATOM 1098 C CE1 . PHE B 1 289 ? 85.503  136.367 146.590 1.00 82.27 ? 378 PHE B CE1 1 
ATOM 1099 C CE2 . PHE B 1 289 ? 84.027  135.832 148.445 1.00 82.27 ? 378 PHE B CE2 1 
ATOM 1100 C CZ  . PHE B 1 289 ? 84.572  136.775 147.558 1.00 82.27 ? 378 PHE B CZ  1 
ATOM 1101 N N   . GLN C 1 218 ? 208.342 147.302 146.705 1.00 76.55 ? 307 GLN C N   1 
ATOM 1102 C CA  . GLN C 1 218 ? 207.882 146.068 146.091 1.00 76.55 ? 307 GLN C CA  1 
ATOM 1103 C C   . GLN C 1 218 ? 206.518 145.622 146.645 1.00 76.55 ? 307 GLN C C   1 
ATOM 1104 O O   . GLN C 1 218 ? 206.349 145.519 147.860 1.00 76.55 ? 307 GLN C O   1 
ATOM 1105 C CB  . GLN C 1 218 ? 208.960 144.983 146.275 1.00 76.55 ? 307 GLN C CB  1 
ATOM 1106 C CG  . GLN C 1 218 ? 208.570 143.626 145.660 1.00 76.55 ? 307 GLN C CG  1 
ATOM 1107 C CD  . GLN C 1 218 ? 209.656 142.556 145.788 1.00 76.55 ? 307 GLN C CD  1 
ATOM 1108 O OE1 . GLN C 1 218 ? 210.643 142.688 146.499 1.00 76.55 ? 307 GLN C OE1 1 
ATOM 1109 N NE2 . GLN C 1 218 ? 209.501 141.429 145.134 1.00 76.55 ? 307 GLN C NE2 1 
ATOM 1110 N N   . ILE C 1 219 ? 205.568 145.310 145.764 1.00 73.45 ? 308 ILE C N   1 
ATOM 1111 C CA  . ILE C 1 219 ? 204.257 144.755 146.119 1.00 73.45 ? 308 ILE C CA  1 
ATOM 1112 C C   . ILE C 1 219 ? 203.982 143.509 145.263 1.00 73.45 ? 308 ILE C C   1 
ATOM 1113 O O   . ILE C 1 219 ? 204.124 143.550 144.042 1.00 73.45 ? 308 ILE C O   1 
ATOM 1114 C CB  . ILE C 1 219 ? 203.153 145.836 145.981 1.00 73.45 ? 308 ILE C CB  1 
ATOM 1115 C CG1 . ILE C 1 219 ? 203.338 147.012 146.971 1.00 73.45 ? 308 ILE C CG1 1 
ATOM 1116 C CG2 . ILE C 1 219 ? 201.764 145.221 146.224 1.00 73.45 ? 308 ILE C CG2 1 
ATOM 1117 C CD1 . ILE C 1 219 ? 204.202 148.167 146.443 1.00 73.45 ? 308 ILE C CD1 1 
ATOM 1118 N N   . VAL C 1 220 ? 203.547 142.415 145.895 1.00 70.22 ? 309 VAL C N   1 
ATOM 1119 C CA  . VAL C 1 220 ? 203.229 141.131 145.245 1.00 70.22 ? 309 VAL C CA  1 
ATOM 1120 C C   . VAL C 1 220 ? 201.785 140.724 145.551 1.00 70.22 ? 309 VAL C C   1 
ATOM 1121 O O   . VAL C 1 220 ? 201.506 139.970 146.483 1.00 70.22 ? 309 VAL C O   1 
ATOM 1122 C CB  . VAL C 1 220 ? 204.260 140.035 145.579 1.00 70.22 ? 309 VAL C CB  1 
ATOM 1123 C CG1 . VAL C 1 220 ? 204.014 138.781 144.739 1.00 70.22 ? 309 VAL C CG1 1 
ATOM 1124 C CG2 . VAL C 1 220 ? 205.688 140.497 145.277 1.00 70.22 ? 309 VAL C CG2 1 
ATOM 1125 N N   . TYR C 1 221 ? 200.841 141.274 144.789 1.00 67.72 ? 310 TYR C N   1 
ATOM 1126 C CA  . TYR C 1 221 ? 199.411 141.017 144.950 1.00 67.72 ? 310 TYR C CA  1 
ATOM 1127 C C   . TYR C 1 221 ? 199.020 139.747 144.180 1.00 67.72 ? 310 TYR C C   1 
ATOM 1128 O O   . TYR C 1 221 ? 198.828 139.770 142.964 1.00 67.72 ? 310 TYR C O   1 
ATOM 1129 C CB  . TYR C 1 221 ? 198.653 142.266 144.486 1.00 67.72 ? 310 TYR C CB  1 
ATOM 1130 C CG  . TYR C 1 221 ? 197.166 142.251 144.776 1.00 67.72 ? 310 TYR C CG  1 
ATOM 1131 C CD1 . TYR C 1 221 ? 196.264 141.690 143.854 1.00 67.72 ? 310 TYR C CD1 1 
ATOM 1132 C CD2 . TYR C 1 221 ? 196.684 142.850 145.952 1.00 67.72 ? 310 TYR C CD2 1 
ATOM 1133 C CE1 . TYR C 1 221 ? 194.881 141.742 144.101 1.00 67.72 ? 310 TYR C CE1 1 
ATOM 1134 C CE2 . TYR C 1 221 ? 195.303 142.915 146.197 1.00 67.72 ? 310 TYR C CE2 1 
ATOM 1135 C CZ  . TYR C 1 221 ? 194.398 142.368 145.267 1.00 67.72 ? 310 TYR C CZ  1 
ATOM 1136 O OH  . TYR C 1 221 ? 193.067 142.443 145.512 1.00 67.72 ? 310 TYR C OH  1 
ATOM 1137 N N   . LYS C 1 222 ? 198.925 138.617 144.884 1.00 64.86 ? 311 LYS C N   1 
ATOM 1138 C CA  . LYS C 1 222 ? 198.848 137.269 144.290 1.00 64.86 ? 311 LYS C CA  1 
ATOM 1139 C C   . LYS C 1 222 ? 197.859 136.331 145.016 1.00 64.86 ? 311 LYS C C   1 
ATOM 1140 O O   . LYS C 1 222 ? 198.252 135.252 145.461 1.00 64.86 ? 311 LYS C O   1 
ATOM 1141 C CB  . LYS C 1 222 ? 200.290 136.723 144.241 1.00 64.86 ? 311 LYS C CB  1 
ATOM 1142 C CG  . LYS C 1 222 ? 200.476 135.540 143.284 1.00 64.86 ? 311 LYS C CG  1 
ATOM 1143 C CD  . LYS C 1 222 ? 201.935 135.083 143.244 1.00 64.86 ? 311 LYS C CD  1 
ATOM 1144 C CE  . LYS C 1 222 ? 202.087 133.932 142.243 1.00 64.86 ? 311 LYS C CE  1 
ATOM 1145 N NZ  . LYS C 1 222 ? 203.478 133.428 142.190 1.00 64.86 ? 311 LYS C NZ  1 
ATOM 1146 N N   . PRO C 1 223 ? 196.580 136.711 145.204 1.00 62.91 ? 312 PRO C N   1 
ATOM 1147 C CA  . PRO C 1 223 ? 195.562 135.804 145.734 1.00 62.91 ? 312 PRO C CA  1 
ATOM 1148 C C   . PRO C 1 223 ? 195.293 134.621 144.789 1.00 62.91 ? 312 PRO C C   1 
ATOM 1149 O O   . PRO C 1 223 ? 195.430 134.746 143.571 1.00 62.91 ? 312 PRO C O   1 
ATOM 1150 C CB  . PRO C 1 223 ? 194.318 136.667 145.953 1.00 62.91 ? 312 PRO C CB  1 
ATOM 1151 C CG  . PRO C 1 223 ? 194.462 137.739 144.885 1.00 62.91 ? 312 PRO C CG  1 
ATOM 1152 C CD  . PRO C 1 223 ? 195.967 137.971 144.819 1.00 62.91 ? 312 PRO C CD  1 
ATOM 1153 N N   . VAL C 1 224 ? 194.859 133.483 145.337 1.00 61.15 ? 313 VAL C N   1 
ATOM 1154 C CA  . VAL C 1 224 ? 194.517 132.264 144.580 1.00 61.15 ? 313 VAL C CA  1 
ATOM 1155 C C   . VAL C 1 224 ? 193.119 131.772 144.964 1.00 61.15 ? 313 VAL C C   1 
ATOM 1156 O O   . VAL C 1 224 ? 192.809 131.656 146.149 1.00 61.15 ? 313 VAL C O   1 
ATOM 1157 C CB  . VAL C 1 224 ? 195.572 131.163 144.805 1.00 61.15 ? 313 VAL C CB  1 
ATOM 1158 C CG1 . VAL C 1 224 ? 195.208 129.841 144.125 1.00 61.15 ? 313 VAL C CG1 1 
ATOM 1159 C CG2 . VAL C 1 224 ? 196.944 131.588 144.279 1.00 61.15 ? 313 VAL C CG2 1 
ATOM 1160 N N   . ASP C 1 225 ? 192.266 131.456 143.987 1.00 59.09 ? 314 ASP C N   1 
ATOM 1161 C CA  . ASP C 1 225 ? 190.912 130.922 144.210 1.00 59.09 ? 314 ASP C CA  1 
ATOM 1162 C C   . ASP C 1 225 ? 190.708 129.553 143.537 1.00 59.09 ? 314 ASP C C   1 
ATOM 1163 O O   . ASP C 1 225 ? 190.850 129.413 142.326 1.00 59.09 ? 314 ASP C O   1 
ATOM 1164 C CB  . ASP C 1 225 ? 189.879 131.966 143.748 1.00 59.09 ? 314 ASP C CB  1 
ATOM 1165 C CG  . ASP C 1 225 ? 188.414 131.532 143.894 1.00 59.09 ? 314 ASP C CG  1 
ATOM 1166 O OD1 . ASP C 1 225 ? 188.117 130.499 144.533 1.00 59.09 ? 314 ASP C OD1 1 
ATOM 1167 O OD2 . ASP C 1 225 ? 187.523 132.270 143.434 1.00 59.09 ? 314 ASP C OD2 1 
ATOM 1168 N N   . LEU C 1 226 ? 190.314 128.562 144.341 1.00 57.53 ? 315 LEU C N   1 
ATOM 1169 C CA  . LEU C 1 226 ? 190.109 127.149 143.997 1.00 57.53 ? 315 LEU C CA  1 
ATOM 1170 C C   . LEU C 1 226 ? 188.675 126.679 144.333 1.00 57.53 ? 315 LEU C C   1 
ATOM 1171 O O   . LEU C 1 226 ? 188.382 125.484 144.295 1.00 57.53 ? 315 LEU C O   1 
ATOM 1172 C CB  . LEU C 1 226 ? 191.151 126.321 144.779 1.00 57.53 ? 315 LEU C CB  1 
ATOM 1173 C CG  . LEU C 1 226 ? 192.625 126.571 144.409 1.00 57.53 ? 315 LEU C CG  1 
ATOM 1174 C CD1 . LEU C 1 226 ? 193.547 126.096 145.525 1.00 57.53 ? 315 LEU C CD1 1 
ATOM 1175 C CD2 . LEU C 1 226 ? 193.004 125.787 143.159 1.00 57.53 ? 315 LEU C CD2 1 
ATOM 1176 N N   . SER C 1 227 ? 187.791 127.602 144.720 1.00 56.45 ? 316 SER C N   1 
ATOM 1177 C CA  . SER C 1 227 ? 186.454 127.329 145.278 1.00 56.45 ? 316 SER C CA  1 
ATOM 1178 C C   . SER C 1 227 ? 185.455 126.682 144.310 1.00 56.45 ? 316 SER C C   1 
ATOM 1179 O O   . SER C 1 227 ? 185.591 126.774 143.089 1.00 56.45 ? 316 SER C O   1 
ATOM 1180 C CB  . SER C 1 227 ? 185.880 128.625 145.852 1.00 56.45 ? 316 SER C CB  1 
ATOM 1181 O OG  . SER C 1 227 ? 185.720 129.594 144.832 1.00 56.45 ? 316 SER C OG  1 
ATOM 1182 N N   . LYS C 1 228 ? 184.411 126.048 144.854 1.00 54.52 ? 317 LYS C N   1 
ATOM 1183 C CA  . LYS C 1 228 ? 183.318 125.419 144.094 1.00 54.52 ? 317 LYS C CA  1 
ATOM 1184 C C   . LYS C 1 228 ? 181.985 125.997 144.595 1.00 54.52 ? 317 LYS C C   1 
ATOM 1185 O O   . LYS C 1 228 ? 181.796 126.140 145.801 1.00 54.52 ? 317 LYS C O   1 
ATOM 1186 C CB  . LYS C 1 228 ? 183.288 123.892 144.329 1.00 54.52 ? 317 LYS C CB  1 
ATOM 1187 C CG  . LYS C 1 228 ? 184.600 123.110 144.162 1.00 54.52 ? 317 LYS C CG  1 
ATOM 1188 C CD  . LYS C 1 228 ? 185.205 123.097 142.756 1.00 54.52 ? 317 LYS C CD  1 
ATOM 1189 C CE  . LYS C 1 228 ? 186.408 122.140 142.706 1.00 54.52 ? 317 LYS C CE  1 
ATOM 1190 N NZ  . LYS C 1 228 ? 187.623 122.687 143.352 1.00 54.52 ? 317 LYS C NZ  1 
ATOM 1191 N N   . VAL C 1 229 ? 181.040 126.274 143.700 1.00 52.89 ? 318 VAL C N   1 
ATOM 1192 C CA  . VAL C 1 229 ? 179.620 126.485 144.039 1.00 52.89 ? 318 VAL C CA  1 
ATOM 1193 C C   . VAL C 1 229 ? 178.799 125.509 143.203 1.00 52.89 ? 318 VAL C C   1 
ATOM 1194 O O   . VAL C 1 229 ? 178.996 125.420 141.995 1.00 52.89 ? 318 VAL C O   1 
ATOM 1195 C CB  . VAL C 1 229 ? 179.190 127.945 143.837 1.00 52.89 ? 318 VAL C CB  1 
ATOM 1196 C CG1 . VAL C 1 229 ? 177.767 128.156 144.355 1.00 52.89 ? 318 VAL C CG1 1 
ATOM 1197 C CG2 . VAL C 1 229 ? 180.107 128.937 144.555 1.00 52.89 ? 318 VAL C CG2 1 
ATOM 1198 N N   . THR C 1 230 ? 177.967 124.673 143.814 1.00 52.42 ? 319 THR C N   1 
ATOM 1199 C CA  . THR C 1 230 ? 177.363 123.500 143.153 1.00 52.42 ? 319 THR C CA  1 
ATOM 1200 C C   . THR C 1 230 ? 175.938 123.235 143.632 1.00 52.42 ? 319 THR C C   1 
ATOM 1201 O O   . THR C 1 230 ? 175.605 123.525 144.779 1.00 52.42 ? 319 THR C O   1 
ATOM 1202 C CB  . THR C 1 230 ? 178.281 122.276 143.343 1.00 52.42 ? 319 THR C CB  1 
ATOM 1203 O OG1 . THR C 1 230 ? 179.487 122.498 142.647 1.00 52.42 ? 319 THR C OG1 1 
ATOM 1204 C CG2 . THR C 1 230 ? 177.747 120.945 142.811 1.00 52.42 ? 319 THR C CG2 1 
ATOM 1205 N N   . SER C 1 231 ? 175.109 122.625 142.781 1.00 49.96 ? 320 SER C N   1 
ATOM 1206 C CA  . SER C 1 231 ? 173.773 122.131 143.143 1.00 49.96 ? 320 SER C CA  1 
ATOM 1207 C C   . SER C 1 231 ? 173.422 120.869 142.362 1.00 49.96 ? 320 SER C C   1 
ATOM 1208 O O   . SER C 1 231 ? 173.800 120.729 141.198 1.00 49.96 ? 320 SER C O   1 
ATOM 1209 C CB  . SER C 1 231 ? 172.688 123.163 142.806 1.00 49.96 ? 320 SER C CB  1 
ATOM 1210 O OG  . SER C 1 231 ? 172.951 124.416 143.394 1.00 49.96 ? 320 SER C OG  1 
ATOM 1211 N N   . LYS C 1 232 ? 172.599 120.011 142.963 1.00 48.44 ? 321 LYS C N   1 
ATOM 1212 C CA  . LYS C 1 232 ? 171.895 118.911 142.299 1.00 48.44 ? 321 LYS C CA  1 
ATOM 1213 C C   . LYS C 1 232 ? 170.420 118.981 142.684 1.00 48.44 ? 321 LYS C C   1 
ATOM 1214 O O   . LYS C 1 232 ? 170.108 119.182 143.855 1.00 48.44 ? 321 LYS C O   1 
ATOM 1215 C CB  . LYS C 1 232 ? 172.508 117.568 142.723 1.00 48.44 ? 321 LYS C CB  1 
ATOM 1216 C CG  . LYS C 1 232 ? 173.957 117.410 142.250 1.00 48.44 ? 321 LYS C CG  1 
ATOM 1217 C CD  . LYS C 1 232 ? 174.494 116.007 142.546 1.00 48.44 ? 321 LYS C CD  1 
ATOM 1218 C CE  . LYS C 1 232 ? 175.933 115.862 142.041 1.00 48.44 ? 321 LYS C CE  1 
ATOM 1219 N NZ  . LYS C 1 232 ? 176.418 114.468 142.176 1.00 48.44 ? 321 LYS C NZ  1 
ATOM 1220 N N   . CYS C 1 233 ? 169.515 118.824 141.728 1.00 47.95 ? 322 CYS C N   1 
ATOM 1221 C CA  . CYS C 1 233 ? 168.075 118.805 141.970 1.00 47.95 ? 322 CYS C CA  1 
ATOM 1222 C C   . CYS C 1 233 ? 167.413 117.668 141.173 1.00 47.95 ? 322 CYS C C   1 
ATOM 1223 O O   . CYS C 1 233 ? 167.617 117.550 139.965 1.00 47.95 ? 322 CYS C O   1 
ATOM 1224 C CB  . CYS C 1 233 ? 167.536 120.200 141.630 1.00 47.95 ? 322 CYS C CB  1 
ATOM 1225 S SG  . CYS C 1 233 ? 165.772 120.324 141.999 1.00 47.95 ? 322 CYS C SG  1 
ATOM 1226 N N   . GLY C 1 234 ? 166.632 116.810 141.826 1.00 46.19 ? 323 GLY C N   1 
ATOM 1227 C CA  . GLY C 1 234 ? 166.105 115.589 141.206 1.00 46.19 ? 323 GLY C CA  1 
ATOM 1228 C C   . GLY C 1 234 ? 164.941 115.815 140.238 1.00 46.19 ? 323 GLY C C   1 
ATOM 1229 O O   . GLY C 1 234 ? 164.826 115.135 139.219 1.00 46.19 ? 323 GLY C O   1 
ATOM 1230 N N   . SER C 1 235 ? 164.078 116.779 140.545 1.00 44.59 ? 324 SER C N   1 
ATOM 1231 C CA  . SER C 1 235 ? 162.966 117.254 139.719 1.00 44.59 ? 324 SER C CA  1 
ATOM 1232 C C   . SER C 1 235 ? 162.442 118.572 140.285 1.00 44.59 ? 324 SER C C   1 
ATOM 1233 O O   . SER C 1 235 ? 162.302 118.694 141.502 1.00 44.59 ? 324 SER C O   1 
ATOM 1234 C CB  . SER C 1 235 ? 161.842 116.218 139.709 1.00 44.59 ? 324 SER C CB  1 
ATOM 1235 O OG  . SER C 1 235 ? 160.788 116.649 138.875 1.00 44.59 ? 324 SER C OG  1 
ATOM 1236 N N   . LEU C 1 236 ? 162.138 119.552 139.438 1.00 42.17 ? 325 LEU C N   1 
ATOM 1237 C CA  . LEU C 1 236 ? 161.685 120.882 139.850 1.00 42.17 ? 325 LEU C CA  1 
ATOM 1238 C C   . LEU C 1 236 ? 160.449 121.291 139.043 1.00 42.17 ? 325 LEU C C   1 
ATOM 1239 O O   . LEU C 1 236 ? 160.507 121.414 137.826 1.00 42.17 ? 325 LEU C O   1 
ATOM 1240 C CB  . LEU C 1 236 ? 162.880 121.849 139.726 1.00 42.17 ? 325 LEU C CB  1 
ATOM 1241 C CG  . LEU C 1 236 ? 162.589 123.326 140.035 1.00 42.17 ? 325 LEU C CG  1 
ATOM 1242 C CD1 . LEU C 1 236 ? 162.003 123.529 141.428 1.00 42.17 ? 325 LEU C CD1 1 
ATOM 1243 C CD2 . LEU C 1 236 ? 163.884 124.129 139.973 1.00 42.17 ? 325 LEU C CD2 1 
ATOM 1244 N N   . GLY C 1 237 ? 159.316 121.509 139.701 1.00 37.85 ? 326 GLY C N   1 
ATOM 1245 C CA  . GLY C 1 237 ? 158.079 121.809 138.987 1.00 37.85 ? 326 GLY C CA  1 
ATOM 1246 C C   . GLY C 1 237 ? 156.816 121.793 139.832 1.00 37.85 ? 326 GLY C C   1 
ATOM 1247 O O   . GLY C 1 237 ? 156.883 121.741 141.057 1.00 37.85 ? 326 GLY C O   1 
ATOM 1248 N N   . ASN C 1 238 ? 155.660 121.827 139.164 1.00 35.20 ? 327 ASN C N   1 
ATOM 1249 C CA  . ASN C 1 238 ? 154.330 121.986 139.766 1.00 35.20 ? 327 ASN C CA  1 
ATOM 1250 C C   . ASN C 1 238 ? 154.226 123.287 140.580 1.00 35.20 ? 327 ASN C C   1 
ATOM 1251 O O   . ASN C 1 238 ? 153.950 123.276 141.778 1.00 35.20 ? 327 ASN C O   1 
ATOM 1252 C CB  . ASN C 1 238 ? 153.929 120.705 140.523 1.00 35.20 ? 327 ASN C CB  1 
ATOM 1253 C CG  . ASN C 1 238 ? 152.466 120.681 140.928 1.00 35.20 ? 327 ASN C CG  1 
ATOM 1254 O OD1 . ASN C 1 238 ? 151.615 121.340 140.352 1.00 35.20 ? 327 ASN C OD1 1 
ATOM 1255 N ND2 . ASN C 1 238 ? 152.115 119.911 141.927 1.00 35.20 ? 327 ASN C ND2 1 
ATOM 1256 N N   . ILE C 1 239 ? 154.523 124.408 139.923 1.00 33.72 ? 328 ILE C N   1 
ATOM 1257 C CA  . ILE C 1 239 ? 154.565 125.755 140.504 1.00 33.72 ? 328 ILE C CA  1 
ATOM 1258 C C   . ILE C 1 239 ? 153.453 126.606 139.883 1.00 33.72 ? 328 ILE C C   1 
ATOM 1259 O O   . ILE C 1 239 ? 153.363 126.734 138.666 1.00 33.72 ? 328 ILE C O   1 
ATOM 1260 C CB  . ILE C 1 239 ? 155.969 126.376 140.333 1.00 33.72 ? 328 ILE C CB  1 
ATOM 1261 C CG1 . ILE C 1 239 ? 157.025 125.615 141.159 1.00 33.72 ? 328 ILE C CG1 1 
ATOM 1262 C CG2 . ILE C 1 239 ? 155.999 127.859 140.712 1.00 33.72 ? 328 ILE C CG2 1 
ATOM 1263 C CD1 . ILE C 1 239 ? 158.429 125.685 140.557 1.00 33.72 ? 328 ILE C CD1 1 
ATOM 1264 N N   . HIS C 1 240 ? 152.606 127.202 140.717 1.00 32.73 ? 329 HIS C N   1 
ATOM 1265 C CA  . HIS C 1 240 ? 151.472 128.031 140.307 1.00 32.73 ? 329 HIS C CA  1 
ATOM 1266 C C   . HIS C 1 240 ? 151.605 129.423 140.903 1.00 32.73 ? 329 HIS C C   1 
ATOM 1267 O O   . HIS C 1 240 ? 151.657 129.559 142.119 1.00 32.73 ? 329 HIS C O   1 
ATOM 1268 C CB  . HIS C 1 240 ? 150.160 127.369 140.747 1.00 32.73 ? 329 HIS C CB  1 
ATOM 1269 C CG  . HIS C 1 240 ? 149.968 125.975 140.211 1.00 32.73 ? 329 HIS C CG  1 
ATOM 1270 N ND1 . HIS C 1 240 ? 149.347 125.647 139.008 1.00 32.73 ? 329 HIS C ND1 1 
ATOM 1271 C CD2 . HIS C 1 240 ? 150.471 124.839 140.768 1.00 32.73 ? 329 HIS C CD2 1 
ATOM 1272 C CE1 . HIS C 1 240 ? 149.503 124.323 138.865 1.00 32.73 ? 329 HIS C CE1 1 
ATOM 1273 N NE2 . HIS C 1 240 ? 150.174 123.815 139.907 1.00 32.73 ? 329 HIS C NE2 1 
ATOM 1274 N N   . HIS C 1 241 ? 151.640 130.463 140.079 1.00 31.87 ? 330 HIS C N   1 
ATOM 1275 C CA  . HIS C 1 241 ? 151.629 131.855 140.516 1.00 31.87 ? 330 HIS C CA  1 
ATOM 1276 C C   . HIS C 1 241 ? 150.399 132.553 139.942 1.00 31.87 ? 330 HIS C C   1 
ATOM 1277 O O   . HIS C 1 241 ? 150.284 132.728 138.730 1.00 31.87 ? 330 HIS C O   1 
ATOM 1278 C CB  . HIS C 1 241 ? 152.949 132.515 140.102 1.00 31.87 ? 330 HIS C CB  1 
ATOM 1279 C CG  . HIS C 1 241 ? 153.148 133.937 140.565 1.00 31.87 ? 330 HIS C CG  1 
ATOM 1280 N ND1 . HIS C 1 241 ? 154.095 134.792 140.074 1.00 31.87 ? 330 HIS C ND1 1 
ATOM 1281 C CD2 . HIS C 1 241 ? 152.562 134.577 141.622 1.00 31.87 ? 330 HIS C CD2 1 
ATOM 1282 C CE1 . HIS C 1 241 ? 154.068 135.926 140.782 1.00 31.87 ? 330 HIS C CE1 1 
ATOM 1283 N NE2 . HIS C 1 241 ? 153.150 135.839 141.751 1.00 31.87 ? 330 HIS C NE2 1 
ATOM 1284 N N   . LYS C 1 242 ? 149.475 132.968 140.807 1.00 31.36 ? 331 LYS C N   1 
ATOM 1285 C CA  . LYS C 1 242 ? 148.121 133.405 140.436 1.00 31.36 ? 331 LYS C CA  1 
ATOM 1286 C C   . LYS C 1 242 ? 147.718 134.695 141.174 1.00 31.36 ? 331 LYS C C   1 
ATOM 1287 O O   . LYS C 1 242 ? 146.953 134.631 142.132 1.00 31.36 ? 331 LYS C O   1 
ATOM 1288 C CB  . LYS C 1 242 ? 147.160 132.231 140.710 1.00 31.36 ? 331 LYS C CB  1 
ATOM 1289 C CG  . LYS C 1 242 ? 147.309 131.059 139.736 1.00 31.36 ? 331 LYS C CG  1 
ATOM 1290 C CD  . LYS C 1 242 ? 146.598 129.791 140.216 1.00 31.36 ? 331 LYS C CD  1 
ATOM 1291 C CE  . LYS C 1 242 ? 145.073 129.937 140.240 1.00 31.36 ? 331 LYS C CE  1 
ATOM 1292 N NZ  . LYS C 1 242 ? 144.430 128.657 140.616 1.00 31.36 ? 331 LYS C NZ  1 
ATOM 1293 N N   . PRO C 1 243 ? 148.236 135.872 140.782 1.00 30.95 ? 332 PRO C N   1 
ATOM 1294 C CA  . PRO C 1 243 ? 147.900 137.158 141.411 1.00 30.95 ? 332 PRO C CA  1 
ATOM 1295 C C   . PRO C 1 243 ? 146.489 137.678 141.104 1.00 30.95 ? 332 PRO C C   1 
ATOM 1296 O O   . PRO C 1 243 ? 146.009 137.564 139.982 1.00 30.95 ? 332 PRO C O   1 
ATOM 1297 C CB  . PRO C 1 243 ? 148.949 138.160 140.917 1.00 30.95 ? 332 PRO C CB  1 
ATOM 1298 C CG  . PRO C 1 243 ? 150.081 137.280 140.421 1.00 30.95 ? 332 PRO C CG  1 
ATOM 1299 C CD  . PRO C 1 243 ? 149.374 136.049 139.900 1.00 30.95 ? 332 PRO C CD  1 
ATOM 1300 N N   . GLY C 1 244 ? 145.840 138.316 142.078 1.00 30.56 ? 333 GLY C N   1 
ATOM 1301 C CA  . GLY C 1 244 ? 144.446 138.780 142.005 1.00 30.56 ? 333 GLY C CA  1 
ATOM 1302 C C   . GLY C 1 244 ? 144.253 140.258 141.666 1.00 30.56 ? 333 GLY C C   1 
ATOM 1303 O O   . GLY C 1 244 ? 143.415 140.921 142.270 1.00 30.56 ? 333 GLY C O   1 
ATOM 1304 N N   . GLY C 1 245 ? 145.017 140.806 140.728 1.00 30.30 ? 334 GLY C N   1 
ATOM 1305 C CA  . GLY C 1 245 ? 144.899 142.206 140.307 1.00 30.30 ? 334 GLY C CA  1 
ATOM 1306 C C   . GLY C 1 245 ? 145.387 143.210 141.353 1.00 30.30 ? 334 GLY C C   1 
ATOM 1307 O O   . GLY C 1 245 ? 146.375 142.966 142.041 1.00 30.30 ? 334 GLY C O   1 
ATOM 1308 N N   . GLY C 1 246 ? 144.700 144.340 141.493 1.00 30.81 ? 335 GLY C N   1 
ATOM 1309 C CA  . GLY C 1 246 ? 145.054 145.416 142.423 1.00 30.81 ? 335 GLY C CA  1 
ATOM 1310 C C   . GLY C 1 246 ? 145.024 146.802 141.789 1.00 30.81 ? 335 GLY C C   1 
ATOM 1311 O O   . GLY C 1 246 ? 144.731 146.951 140.605 1.00 30.81 ? 335 GLY C O   1 
ATOM 1312 N N   . GLN C 1 247 ? 145.306 147.836 142.574 1.00 32.29 ? 336 GLN C N   1 
ATOM 1313 C CA  . GLN C 1 247 ? 145.265 149.221 142.103 1.00 32.29 ? 336 GLN C CA  1 
ATOM 1314 C C   . GLN C 1 247 ? 146.347 150.118 142.720 1.00 32.29 ? 336 GLN C C   1 
ATOM 1315 O O   . GLN C 1 247 ? 146.594 150.042 143.921 1.00 32.29 ? 336 GLN C O   1 
ATOM 1316 C CB  . GLN C 1 247 ? 143.860 149.752 142.363 1.00 32.29 ? 336 GLN C CB  1 
ATOM 1317 C CG  . GLN C 1 247 ? 143.582 151.078 141.662 1.00 32.29 ? 336 GLN C CG  1 
ATOM 1318 C CD  . GLN C 1 247 ? 142.088 151.293 141.625 1.00 32.29 ? 336 GLN C CD  1 
ATOM 1319 O OE1 . GLN C 1 247 ? 141.509 151.707 142.606 1.00 32.29 ? 336 GLN C OE1 1 
ATOM 1320 N NE2 . GLN C 1 247 ? 141.413 151.044 140.533 1.00 32.29 ? 336 GLN C NE2 1 
ATOM 1321 N N   . VAL C 1 248 ? 146.968 150.984 141.913 1.00 34.23 ? 337 VAL C N   1 
ATOM 1322 C CA  . VAL C 1 248 ? 148.062 151.897 142.302 1.00 34.23 ? 337 VAL C CA  1 
ATOM 1323 C C   . VAL C 1 248 ? 147.824 153.309 141.766 1.00 34.23 ? 337 VAL C C   1 
ATOM 1324 O O   . VAL C 1 248 ? 147.517 153.478 140.593 1.00 34.23 ? 337 VAL C O   1 
ATOM 1325 C CB  . VAL C 1 248 ? 149.430 151.367 141.814 1.00 34.23 ? 337 VAL C CB  1 
ATOM 1326 C CG1 . VAL C 1 248 ? 150.594 152.286 142.192 1.00 34.23 ? 337 VAL C CG1 1 
ATOM 1327 C CG2 . VAL C 1 248 ? 149.743 149.989 142.393 1.00 34.23 ? 337 VAL C CG2 1 
ATOM 1328 N N   . GLU C 1 249 ? 148.027 154.333 142.591 1.00 37.82 ? 338 GLU C N   1 
ATOM 1329 C CA  . GLU C 1 249 ? 147.959 155.741 142.192 1.00 37.82 ? 338 GLU C CA  1 
ATOM 1330 C C   . GLU C 1 249 ? 149.128 156.547 142.766 1.00 37.82 ? 338 GLU C C   1 
ATOM 1331 O O   . GLU C 1 249 ? 149.405 156.453 143.960 1.00 37.82 ? 338 GLU C O   1 
ATOM 1332 C CB  . GLU C 1 249 ? 146.610 156.314 142.639 1.00 37.82 ? 338 GLU C CB  1 
ATOM 1333 C CG  . GLU C 1 249 ? 146.437 157.799 142.291 1.00 37.82 ? 338 GLU C CG  1 
ATOM 1334 C CD  . GLU C 1 249 ? 145.040 158.331 142.641 1.00 37.82 ? 338 GLU C CD  1 
ATOM 1335 O OE1 . GLU C 1 249 ? 144.086 157.538 142.814 1.00 37.82 ? 338 GLU C OE1 1 
ATOM 1336 O OE2 . GLU C 1 249 ? 144.888 159.565 142.769 1.00 37.82 ? 338 GLU C OE2 1 
ATOM 1337 N N   . VAL C 1 250 ? 149.781 157.381 141.953 1.00 39.64 ? 339 VAL C N   1 
ATOM 1338 C CA  . VAL C 1 250 ? 150.890 158.257 142.379 1.00 39.64 ? 339 VAL C CA  1 
ATOM 1339 C C   . VAL C 1 250 ? 150.725 159.674 141.827 1.00 39.64 ? 339 VAL C C   1 
ATOM 1340 O O   . VAL C 1 250 ? 150.412 159.857 140.654 1.00 39.64 ? 339 VAL C O   1 
ATOM 1341 C CB  . VAL C 1 250 ? 152.264 157.673 141.984 1.00 39.64 ? 339 VAL C CB  1 
ATOM 1342 C CG1 . VAL C 1 250 ? 153.401 158.531 142.545 1.00 39.64 ? 339 VAL C CG1 1 
ATOM 1343 C CG2 . VAL C 1 250 ? 152.479 156.246 142.498 1.00 39.64 ? 339 VAL C CG2 1 
ATOM 1344 N N   . LYS C 1 251 ? 150.971 160.691 142.652 1.00 43.73 ? 340 LYS C N   1 
ATOM 1345 C CA  . LYS C 1 251 ? 150.864 162.111 142.291 1.00 43.73 ? 340 LYS C CA  1 
ATOM 1346 C C   . LYS C 1 251 ? 152.146 162.852 142.686 1.00 43.73 ? 340 LYS C C   1 
ATOM 1347 O O   . LYS C 1 251 ? 152.631 162.686 143.803 1.00 43.73 ? 340 LYS C O   1 
ATOM 1348 C CB  . LYS C 1 251 ? 149.630 162.674 143.010 1.00 43.73 ? 340 LYS C CB  1 
ATOM 1349 C CG  . LYS C 1 251 ? 149.272 164.111 142.610 1.00 43.73 ? 340 LYS C CG  1 
ATOM 1350 C CD  . LYS C 1 251 ? 148.043 164.624 143.376 1.00 43.73 ? 340 LYS C CD  1 
ATOM 1351 C CE  . LYS C 1 251 ? 146.743 163.868 143.071 1.00 43.73 ? 340 LYS C CE  1 
ATOM 1352 N NZ  . LYS C 1 251 ? 145.591 164.484 143.776 1.00 43.73 ? 340 LYS C NZ  1 
ATOM 1353 N N   . SER C 1 252 ? 152.657 163.711 141.809 1.00 48.33 ? 341 SER C N   1 
ATOM 1354 C CA  . SER C 1 252 ? 153.860 164.529 142.030 1.00 48.33 ? 341 SER C CA  1 
ATOM 1355 C C   . SER C 1 252 ? 153.697 165.907 141.385 1.00 48.33 ? 341 SER C C   1 
ATOM 1356 O O   . SER C 1 252 ? 152.976 166.052 140.403 1.00 48.33 ? 341 SER C O   1 
ATOM 1357 C CB  . SER C 1 252 ? 155.087 163.846 141.405 1.00 48.33 ? 341 SER C CB  1 
ATOM 1358 O OG  . SER C 1 252 ? 155.377 162.609 142.027 1.00 48.33 ? 341 SER C OG  1 
ATOM 1359 N N   . GLU C 1 253 ? 154.408 166.925 141.872 1.00 51.70 ? 342 GLU C N   1 
ATOM 1360 C CA  . GLU C 1 253 ? 154.535 168.183 141.121 1.00 51.70 ? 342 GLU C CA  1 
ATOM 1361 C C   . GLU C 1 253 ? 155.747 168.117 140.181 1.00 51.70 ? 342 GLU C C   1 
ATOM 1362 O O   . GLU C 1 253 ? 155.603 168.228 138.969 1.00 51.70 ? 342 GLU C O   1 
ATOM 1363 C CB  . GLU C 1 253 ? 154.684 169.383 142.075 1.00 51.70 ? 342 GLU C CB  1 
ATOM 1364 C CG  . GLU C 1 253 ? 153.575 169.550 143.127 1.00 51.70 ? 342 GLU C CG  1 
ATOM 1365 C CD  . GLU C 1 253 ? 152.182 169.861 142.556 1.00 51.70 ? 342 GLU C CD  1 
ATOM 1366 O OE1 . GLU C 1 253 ? 152.075 170.440 141.454 1.00 51.70 ? 342 GLU C OE1 1 
ATOM 1367 O OE2 . GLU C 1 253 ? 151.177 169.570 143.246 1.00 51.70 ? 342 GLU C OE2 1 
ATOM 1368 N N   . LYS C 1 254 ? 156.938 167.826 140.710 1.00 51.77 ? 343 LYS C N   1 
ATOM 1369 C CA  . LYS C 1 254 ? 158.204 167.879 139.963 1.00 51.77 ? 343 LYS C CA  1 
ATOM 1370 C C   . LYS C 1 254 ? 159.115 166.723 140.343 1.00 51.77 ? 343 LYS C C   1 
ATOM 1371 O O   . LYS C 1 254 ? 159.236 166.418 141.526 1.00 51.77 ? 343 LYS C O   1 
ATOM 1372 C CB  . LYS C 1 254 ? 158.927 169.199 140.275 1.00 51.77 ? 343 LYS C CB  1 
ATOM 1373 C CG  . LYS C 1 254 ? 158.136 170.445 139.862 1.00 51.77 ? 343 LYS C CG  1 
ATOM 1374 C CD  . LYS C 1 254 ? 159.010 171.691 140.007 1.00 51.77 ? 343 LYS C CD  1 
ATOM 1375 C CE  . LYS C 1 254 ? 158.220 172.943 139.615 1.00 51.77 ? 343 LYS C CE  1 
ATOM 1376 N NZ  . LYS C 1 254 ? 159.067 174.157 139.673 1.00 51.77 ? 343 LYS C NZ  1 
ATOM 1377 N N   . LEU C 1 255 ? 159.812 166.143 139.372 1.00 51.04 ? 344 LEU C N   1 
ATOM 1378 C CA  . LEU C 1 255 ? 160.920 165.214 139.598 1.00 51.04 ? 344 LEU C CA  1 
ATOM 1379 C C   . LEU C 1 255 ? 162.189 165.724 138.915 1.00 51.04 ? 344 LEU C C   1 
ATOM 1380 O O   . LEU C 1 255 ? 162.160 166.147 137.764 1.00 51.04 ? 344 LEU C O   1 
ATOM 1381 C CB  . LEU C 1 255 ? 160.548 163.790 139.153 1.00 51.04 ? 344 LEU C CB  1 
ATOM 1382 C CG  . LEU C 1 255 ? 159.264 163.205 139.773 1.00 51.04 ? 344 LEU C CG  1 
ATOM 1383 C CD1 . LEU C 1 255 ? 158.996 161.811 139.221 1.00 51.04 ? 344 LEU C CD1 1 
ATOM 1384 C CD2 . LEU C 1 255 ? 159.374 163.022 141.286 1.00 51.04 ? 344 LEU C CD2 1 
ATOM 1385 N N   . ASP C 1 256 ? 163.310 165.670 139.626 1.00 51.16 ? 345 ASP C N   1 
ATOM 1386 C CA  . ASP C 1 256 ? 164.587 166.267 139.228 1.00 51.16 ? 345 ASP C CA  1 
ATOM 1387 C C   . ASP C 1 256 ? 165.741 165.356 139.659 1.00 51.16 ? 345 ASP C C   1 
ATOM 1388 O O   . ASP C 1 256 ? 166.137 165.352 140.821 1.00 51.16 ? 345 ASP C O   1 
ATOM 1389 C CB  . ASP C 1 256 ? 164.650 167.678 139.833 1.00 51.16 ? 345 ASP C CB  1 
ATOM 1390 C CG  . ASP C 1 256 ? 165.880 168.500 139.440 1.00 51.16 ? 345 ASP C CG  1 
ATOM 1391 O OD1 . ASP C 1 256 ? 166.764 167.997 138.721 1.00 51.16 ? 345 ASP C OD1 1 
ATOM 1392 O OD2 . ASP C 1 256 ? 165.953 169.678 139.855 1.00 51.16 ? 345 ASP C OD2 1 
ATOM 1393 N N   . PHE C 1 257 ? 166.228 164.523 138.741 1.00 48.98 ? 346 PHE C N   1 
ATOM 1394 C CA  . PHE C 1 257 ? 167.200 163.458 139.006 1.00 48.98 ? 346 PHE C CA  1 
ATOM 1395 C C   . PHE C 1 257 ? 168.551 163.751 138.353 1.00 48.98 ? 346 PHE C C   1 
ATOM 1396 O O   . PHE C 1 257 ? 168.608 164.027 137.159 1.00 48.98 ? 346 PHE C O   1 
ATOM 1397 C CB  . PHE C 1 257 ? 166.661 162.100 138.528 1.00 48.98 ? 346 PHE C CB  1 
ATOM 1398 C CG  . PHE C 1 257 ? 165.355 161.592 139.121 1.00 48.98 ? 346 PHE C CG  1 
ATOM 1399 C CD1 . PHE C 1 257 ? 164.806 162.131 140.297 1.00 48.98 ? 346 PHE C CD1 1 
ATOM 1400 C CD2 . PHE C 1 257 ? 164.682 160.542 138.474 1.00 48.98 ? 346 PHE C CD2 1 
ATOM 1401 C CE1 . PHE C 1 257 ? 163.574 161.666 140.781 1.00 48.98 ? 346 PHE C CE1 1 
ATOM 1402 C CE2 . PHE C 1 257 ? 163.454 160.071 138.959 1.00 48.98 ? 346 PHE C CE2 1 
ATOM 1403 C CZ  . PHE C 1 257 ? 162.896 160.640 140.111 1.00 48.98 ? 346 PHE C CZ  1 
ATOM 1404 N N   . LYS C 1 258 ? 169.645 163.645 139.114 1.00 49.85 ? 347 LYS C N   1 
ATOM 1405 C CA  . LYS C 1 258 ? 171.017 163.874 138.638 1.00 49.85 ? 347 LYS C CA  1 
ATOM 1406 C C   . LYS C 1 258 ? 171.953 162.752 139.065 1.00 49.85 ? 347 LYS C C   1 
ATOM 1407 O O   . LYS C 1 258 ? 171.876 162.326 140.209 1.00 49.85 ? 347 LYS C O   1 
ATOM 1408 C CB  . LYS C 1 258 ? 171.570 165.194 139.196 1.00 49.85 ? 347 LYS C CB  1 
ATOM 1409 C CG  . LYS C 1 258 ? 170.739 166.430 138.844 1.00 49.85 ? 347 LYS C CG  1 
ATOM 1410 C CD  . LYS C 1 258 ? 171.451 167.685 139.355 1.00 49.85 ? 347 LYS C CD  1 
ATOM 1411 C CE  . LYS C 1 258 ? 170.591 168.923 139.092 1.00 49.85 ? 347 LYS C CE  1 
ATOM 1412 N NZ  . LYS C 1 258 ? 171.317 170.171 139.432 1.00 49.85 ? 347 LYS C NZ  1 
ATOM 1413 N N   . ASP C 1 259 ? 172.909 162.380 138.219 1.00 48.93 ? 348 ASP C N   1 
ATOM 1414 C CA  . ASP C 1 259 ? 174.122 161.632 138.583 1.00 48.93 ? 348 ASP C CA  1 
ATOM 1415 C C   . ASP C 1 259 ? 173.873 160.273 139.269 1.00 48.93 ? 348 ASP C C   1 
ATOM 1416 O O   . ASP C 1 259 ? 173.848 160.181 140.495 1.00 48.93 ? 348 ASP C O   1 
ATOM 1417 C CB  . ASP C 1 259 ? 175.049 162.542 139.406 1.00 48.93 ? 348 ASP C CB  1 
ATOM 1418 C CG  . ASP C 1 259 ? 176.375 161.871 139.773 1.00 48.93 ? 348 ASP C CG  1 
ATOM 1419 O OD1 . ASP C 1 259 ? 176.802 160.910 139.100 1.00 48.93 ? 348 ASP C OD1 1 
ATOM 1420 O OD2 . ASP C 1 259 ? 177.011 162.287 140.767 1.00 48.93 ? 348 ASP C OD2 1 
ATOM 1421 N N   . ARG C 1 260 ? 173.751 159.198 138.481 1.00 47.08 ? 349 ARG C N   1 
ATOM 1422 C CA  . ARG C 1 260 ? 173.609 157.804 138.961 1.00 47.08 ? 349 ARG C CA  1 
ATOM 1423 C C   . ARG C 1 260 ? 172.365 157.581 139.830 1.00 47.08 ? 349 ARG C C   1 
ATOM 1424 O O   . ARG C 1 260 ? 172.448 157.144 140.975 1.00 47.08 ? 349 ARG C O   1 
ATOM 1425 C CB  . ARG C 1 260 ? 174.910 157.313 139.626 1.00 47.08 ? 349 ARG C CB  1 
ATOM 1426 C CG  . ARG C 1 260 ? 176.091 157.239 138.650 1.00 47.08 ? 349 ARG C CG  1 
ATOM 1427 C CD  . ARG C 1 260 ? 177.423 157.181 139.400 1.00 47.08 ? 349 ARG C CD  1 
ATOM 1428 N NE  . ARG C 1 260 ? 177.725 158.483 140.022 1.00 47.08 ? 349 ARG C NE  1 
ATOM 1429 C CZ  . ARG C 1 260 ? 178.391 158.721 141.133 1.00 47.08 ? 349 ARG C CZ  1 
ATOM 1430 N NH1 . ARG C 1 260 ? 179.042 157.790 141.764 1.00 47.08 ? 349 ARG C NH1 1 
ATOM 1431 N NH2 . ARG C 1 260 ? 178.418 159.922 141.624 1.00 47.08 ? 349 ARG C NH2 1 
ATOM 1432 N N   . VAL C 1 261 ? 171.192 157.867 139.268 1.00 44.97 ? 350 VAL C N   1 
ATOM 1433 C CA  . VAL C 1 261 ? 169.884 157.591 139.887 1.00 44.97 ? 350 VAL C CA  1 
ATOM 1434 C C   . VAL C 1 261 ? 169.243 156.377 139.233 1.00 44.97 ? 350 VAL C C   1 
ATOM 1435 O O   . VAL C 1 261 ? 169.117 156.336 138.016 1.00 44.97 ? 350 VAL C O   1 
ATOM 1436 C CB  . VAL C 1 261 ? 168.947 158.811 139.807 1.00 44.97 ? 350 VAL C CB  1 
ATOM 1437 C CG1 . VAL C 1 261 ? 167.536 158.527 140.328 1.00 44.97 ? 350 VAL C CG1 1 
ATOM 1438 C CG2 . VAL C 1 261 ? 169.521 159.967 140.623 1.00 44.97 ? 350 VAL C CG2 1 
ATOM 1439 N N   . GLN C 1 262 ? 168.787 155.414 140.028 1.00 42.16 ? 351 GLN C N   1 
ATOM 1440 C CA  . GLN C 1 262 ? 167.902 154.337 139.587 1.00 42.16 ? 351 GLN C CA  1 
ATOM 1441 C C   . GLN C 1 262 ? 166.545 154.481 140.295 1.00 42.16 ? 351 GLN C C   1 
ATOM 1442 O O   . GLN C 1 262 ? 166.481 154.440 141.521 1.00 42.16 ? 351 GLN C O   1 
ATOM 1443 C CB  . GLN C 1 262 ? 168.605 153.000 139.839 1.00 42.16 ? 351 GLN C CB  1 
ATOM 1444 C CG  . GLN C 1 262 ? 167.772 151.804 139.363 1.00 42.16 ? 351 GLN C CG  1 
ATOM 1445 C CD  . GLN C 1 262 ? 168.444 150.454 139.608 1.00 42.16 ? 351 GLN C CD  1 
ATOM 1446 O OE1 . GLN C 1 262 ? 167.792 149.461 139.900 1.00 42.16 ? 351 GLN C OE1 1 
ATOM 1447 N NE2 . GLN C 1 262 ? 169.753 150.347 139.538 1.00 42.16 ? 351 GLN C NE2 1 
ATOM 1448 N N   . SER C 1 263 ? 165.465 154.675 139.540 1.00 40.18 ? 352 SER C N   1 
ATOM 1449 C CA  . SER C 1 263 ? 164.145 155.039 140.077 1.00 40.18 ? 352 SER C CA  1 
ATOM 1450 C C   . SER C 1 263 ? 163.004 154.231 139.460 1.00 40.18 ? 352 SER C C   1 
ATOM 1451 O O   . SER C 1 263 ? 163.002 153.959 138.262 1.00 40.18 ? 352 SER C O   1 
ATOM 1452 C CB  . SER C 1 263 ? 163.922 156.541 139.900 1.00 40.18 ? 352 SER C CB  1 
ATOM 1453 O OG  . SER C 1 263 ? 162.711 156.938 140.507 1.00 40.18 ? 352 SER C OG  1 
ATOM 1454 N N   . LYS C 1 264 ? 162.015 153.857 140.274 1.00 38.04 ? 353 LYS C N   1 
ATOM 1455 C CA  . LYS C 1 264 ? 160.791 153.149 139.871 1.00 38.04 ? 353 LYS C CA  1 
ATOM 1456 C C   . LYS C 1 264 ? 159.575 153.784 140.550 1.00 38.04 ? 353 LYS C C   1 
ATOM 1457 O O   . LYS C 1 264 ? 159.517 153.803 141.775 1.00 38.04 ? 353 LYS C O   1 
ATOM 1458 C CB  . LYS C 1 264 ? 160.982 151.666 140.217 1.00 38.04 ? 353 LYS C CB  1 
ATOM 1459 C CG  . LYS C 1 264 ? 159.909 150.741 139.639 1.00 38.04 ? 353 LYS C CG  1 
ATOM 1460 C CD  . LYS C 1 264 ? 160.163 149.306 140.119 1.00 38.04 ? 353 LYS C CD  1 
ATOM 1461 C CE  . LYS C 1 264 ? 159.183 148.318 139.479 1.00 38.04 ? 353 LYS C CE  1 
ATOM 1462 N NZ  . LYS C 1 264 ? 159.287 146.974 140.094 1.00 38.04 ? 353 LYS C NZ  1 
ATOM 1463 N N   . ILE C 1 265 ? 158.624 154.321 139.785 1.00 38.55 ? 354 ILE C N   1 
ATOM 1464 C CA  . ILE C 1 265 ? 157.452 155.061 140.295 1.00 38.55 ? 354 ILE C CA  1 
ATOM 1465 C C   . ILE C 1 265 ? 156.152 154.494 139.721 1.00 38.55 ? 354 ILE C C   1 
ATOM 1466 O O   . ILE C 1 265 ? 155.974 154.482 138.509 1.00 38.55 ? 354 ILE C O   1 
ATOM 1467 C CB  . ILE C 1 265 ? 157.586 156.573 139.996 1.00 38.55 ? 354 ILE C CB  1 
ATOM 1468 C CG1 . ILE C 1 265 ? 158.887 157.136 140.601 1.00 38.55 ? 354 ILE C CG1 1 
ATOM 1469 C CG2 . ILE C 1 265 ? 156.375 157.361 140.516 1.00 38.55 ? 354 ILE C CG2 1 
ATOM 1470 C CD1 . ILE C 1 265 ? 159.138 158.608 140.295 1.00 38.55 ? 354 ILE C CD1 1 
ATOM 1471 N N   . GLY C 1 266 ? 155.222 154.070 140.576 1.00 37.46 ? 355 GLY C N   1 
ATOM 1472 C CA  . GLY C 1 266 ? 153.898 153.580 140.177 1.00 37.46 ? 355 GLY C CA  1 
ATOM 1473 C C   . GLY C 1 266 ? 153.948 152.300 139.345 1.00 37.46 ? 355 GLY C C   1 
ATOM 1474 O O   . GLY C 1 266 ? 153.891 152.344 138.122 1.00 37.46 ? 355 GLY C O   1 
ATOM 1475 N N   . SER C 1 267 ? 154.038 151.139 139.985 1.00 36.13 ? 356 SER C N   1 
ATOM 1476 C CA  . SER C 1 267 ? 154.106 149.853 139.280 1.00 36.13 ? 356 SER C CA  1 
ATOM 1477 C C   . SER C 1 267 ? 153.196 148.779 139.867 1.00 36.13 ? 356 SER C C   1 
ATOM 1478 O O   . SER C 1 267 ? 152.916 148.778 141.062 1.00 36.13 ? 356 SER C O   1 
ATOM 1479 C CB  . SER C 1 267 ? 155.554 149.382 139.190 1.00 36.13 ? 356 SER C CB  1 
ATOM 1480 O OG  . SER C 1 267 ? 156.038 148.985 140.458 1.00 36.13 ? 356 SER C OG  1 
ATOM 1481 N N   . LEU C 1 268 ? 152.772 147.832 139.035 1.00 34.62 ? 357 LEU C N   1 
ATOM 1482 C CA  . LEU C 1 268 ? 152.033 146.633 139.431 1.00 34.62 ? 357 LEU C CA  1 
ATOM 1483 C C   . LEU C 1 268 ? 152.619 145.451 138.644 1.00 34.62 ? 357 LEU C C   1 
ATOM 1484 O O   . LEU C 1 268 ? 152.046 144.965 137.675 1.00 34.62 ? 357 LEU C O   1 
ATOM 1485 C CB  . LEU C 1 268 ? 150.531 146.907 139.208 1.00 34.62 ? 357 LEU C CB  1 
ATOM 1486 C CG  . LEU C 1 268 ? 149.538 145.983 139.939 1.00 34.62 ? 357 LEU C CG  1 
ATOM 1487 C CD1 . LEU C 1 268 ? 148.167 146.651 139.942 1.00 34.62 ? 357 LEU C CD1 1 
ATOM 1488 C CD2 . LEU C 1 268 ? 149.362 144.602 139.319 1.00 34.62 ? 357 LEU C CD2 1 
ATOM 1489 N N   . ASP C 1 269 ? 153.813 145.020 139.049 1.00 35.46 ? 358 ASP C N   1 
ATOM 1490 C CA  . ASP C 1 269 ? 154.647 144.086 138.289 1.00 35.46 ? 358 ASP C CA  1 
ATOM 1491 C C   . ASP C 1 269 ? 154.692 142.691 138.945 1.00 35.46 ? 358 ASP C C   1 
ATOM 1492 O O   . ASP C 1 269 ? 154.873 142.590 140.154 1.00 35.46 ? 358 ASP C O   1 
ATOM 1493 C CB  . ASP C 1 269 ? 156.058 144.665 138.076 1.00 35.46 ? 358 ASP C CB  1 
ATOM 1494 C CG  . ASP C 1 269 ? 156.161 145.988 137.282 1.00 35.46 ? 358 ASP C CG  1 
ATOM 1495 O OD1 . ASP C 1 269 ? 155.195 146.445 136.633 1.00 35.46 ? 358 ASP C OD1 1 
ATOM 1496 O OD2 . ASP C 1 269 ? 157.282 146.551 137.261 1.00 35.46 ? 358 ASP C OD2 1 
ATOM 1497 N N   . ASN C 1 270 ? 154.523 141.613 138.173 1.00 32.98 ? 359 ASN C N   1 
ATOM 1498 C CA  . ASN C 1 270 ? 154.546 140.215 138.635 1.00 32.98 ? 359 ASN C CA  1 
ATOM 1499 C C   . ASN C 1 270 ? 155.719 139.430 138.032 1.00 32.98 ? 359 ASN C C   1 
ATOM 1500 O O   . ASN C 1 270 ? 155.917 139.468 136.822 1.00 32.98 ? 359 ASN C O   1 
ATOM 1501 C CB  . ASN C 1 270 ? 153.221 139.515 138.293 1.00 32.98 ? 359 ASN C CB  1 
ATOM 1502 C CG  . ASN C 1 270 ? 151.997 140.200 138.860 1.00 32.98 ? 359 ASN C CG  1 
ATOM 1503 O OD1 . ASN C 1 270 ? 151.793 140.260 140.059 1.00 32.98 ? 359 ASN C OD1 1 
ATOM 1504 N ND2 . ASN C 1 270 ? 151.156 140.750 138.024 1.00 32.98 ? 359 ASN C ND2 1 
ATOM 1505 N N   . ILE C 1 271 ? 156.476 138.677 138.834 1.00 31.86 ? 360 ILE C N   1 
ATOM 1506 C CA  . ILE C 1 271 ? 157.628 137.887 138.361 1.00 31.86 ? 360 ILE C CA  1 
ATOM 1507 C C   . ILE C 1 271 ? 157.501 136.438 138.830 1.00 31.86 ? 360 ILE C C   1 
ATOM 1508 O O   . ILE C 1 271 ? 157.285 136.187 140.008 1.00 31.86 ? 360 ILE C O   1 
ATOM 1509 C CB  . ILE C 1 271 ? 158.981 138.507 138.800 1.00 31.86 ? 360 ILE C CB  1 
ATOM 1510 C CG1 . ILE C 1 271 ? 159.122 139.959 138.292 1.00 31.86 ? 360 ILE C CG1 1 
ATOM 1511 C CG2 . ILE C 1 271 ? 160.160 137.660 138.292 1.00 31.86 ? 360 ILE C CG2 1 
ATOM 1512 C CD1 . ILE C 1 271 ? 160.360 140.694 138.801 1.00 31.86 ? 360 ILE C CD1 1 
ATOM 1513 N N   . THR C 1 272 ? 157.691 135.478 137.927 1.00 32.83 ? 361 THR C N   1 
ATOM 1514 C CA  . THR C 1 272 ? 157.904 134.065 138.264 1.00 32.83 ? 361 THR C CA  1 
ATOM 1515 C C   . THR C 1 272 ? 159.300 133.680 137.795 1.00 32.83 ? 361 THR C C   1 
ATOM 1516 O O   . THR C 1 272 ? 159.566 133.739 136.601 1.00 32.83 ? 361 THR C O   1 
ATOM 1517 C CB  . THR C 1 272 ? 156.863 133.175 137.571 1.00 32.83 ? 361 THR C CB  1 
ATOM 1518 O OG1 . THR C 1 272 ? 155.567 133.595 137.901 1.00 32.83 ? 361 THR C OG1 1 
ATOM 1519 C CG2 . THR C 1 272 ? 156.965 131.720 138.000 1.00 32.83 ? 361 THR C CG2 1 
ATOM 1520 N N   . HIS C 1 273 ? 160.213 133.324 138.697 1.00 34.46 ? 362 HIS C N   1 
ATOM 1521 C CA  . HIS C 1 273 ? 161.609 133.009 138.360 1.00 34.46 ? 362 HIS C CA  1 
ATOM 1522 C C   . HIS C 1 273 ? 162.010 131.633 138.896 1.00 34.46 ? 362 HIS C C   1 
ATOM 1523 O O   . HIS C 1 273 ? 162.035 131.422 140.103 1.00 34.46 ? 362 HIS C O   1 
ATOM 1524 C CB  . HIS C 1 273 ? 162.519 134.143 138.856 1.00 34.46 ? 362 HIS C CB  1 
ATOM 1525 C CG  . HIS C 1 273 ? 163.971 133.998 138.478 1.00 34.46 ? 362 HIS C CG  1 
ATOM 1526 N ND1 . HIS C 1 273 ? 164.457 133.402 137.318 1.00 34.46 ? 362 HIS C ND1 1 
ATOM 1527 C CD2 . HIS C 1 273 ? 165.023 134.489 139.187 1.00 34.46 ? 362 HIS C CD2 1 
ATOM 1528 C CE1 . HIS C 1 273 ? 165.790 133.535 137.360 1.00 34.46 ? 362 HIS C CE1 1 
ATOM 1529 N NE2 . HIS C 1 273 ? 166.156 134.182 138.473 1.00 34.46 ? 362 HIS C NE2 1 
ATOM 1530 N N   . VAL C 1 274 ? 162.310 130.689 138.007 1.00 36.17 ? 363 VAL C N   1 
ATOM 1531 C CA  . VAL C 1 274 ? 162.516 129.270 138.333 1.00 36.17 ? 363 VAL C CA  1 
ATOM 1532 C C   . VAL C 1 274 ? 163.777 128.749 137.630 1.00 36.17 ? 363 VAL C C   1 
ATOM 1533 O O   . VAL C 1 274 ? 163.681 128.003 136.663 1.00 36.17 ? 363 VAL C O   1 
ATOM 1534 C CB  . VAL C 1 274 ? 161.264 128.413 138.019 1.00 36.17 ? 363 VAL C CB  1 
ATOM 1535 C CG1 . VAL C 1 274 ? 161.397 127.005 138.604 1.00 36.17 ? 363 VAL C CG1 1 
ATOM 1536 C CG2 . VAL C 1 274 ? 159.957 128.987 138.568 1.00 36.17 ? 363 VAL C CG2 1 
ATOM 1537 N N   . PRO C 1 275 ? 164.981 129.152 138.065 1.00 38.35 ? 364 PRO C N   1 
ATOM 1538 C CA  . PRO C 1 275 ? 166.215 128.653 137.485 1.00 38.35 ? 364 PRO C CA  1 
ATOM 1539 C C   . PRO C 1 275 ? 166.491 127.207 137.904 1.00 38.35 ? 364 PRO C C   1 
ATOM 1540 O O   . PRO C 1 275 ? 166.310 126.841 139.064 1.00 38.35 ? 364 PRO C O   1 
ATOM 1541 C CB  . PRO C 1 275 ? 167.297 129.616 137.982 1.00 38.35 ? 364 PRO C CB  1 
ATOM 1542 C CG  . PRO C 1 275 ? 166.771 130.080 139.334 1.00 38.35 ? 364 PRO C CG  1 
ATOM 1543 C CD  . PRO C 1 275 ? 165.261 130.103 139.127 1.00 38.35 ? 364 PRO C CD  1 
ATOM 1544 N N   . GLY C 1 276 ? 167.000 126.389 136.985 1.00 42.41 ? 365 GLY C N   1 
ATOM 1545 C CA  . GLY C 1 276 ? 167.424 125.020 137.290 1.00 42.41 ? 365 GLY C CA  1 
ATOM 1546 C C   . GLY C 1 276 ? 168.662 124.939 138.194 1.00 42.41 ? 365 GLY C C   1 
ATOM 1547 O O   . GLY C 1 276 ? 168.823 123.972 138.935 1.00 42.41 ? 365 GLY C O   1 
ATOM 1548 N N   . GLY C 1 277 ? 169.518 125.960 138.171 1.00 44.65 ? 366 GLY C N   1 
ATOM 1549 C CA  . GLY C 1 277 ? 170.664 126.133 139.058 1.00 44.65 ? 366 GLY C CA  1 
ATOM 1550 C C   . GLY C 1 277 ? 170.521 127.365 139.939 1.00 44.65 ? 366 GLY C C   1 
ATOM 1551 O O   . GLY C 1 277 ? 170.183 127.253 141.112 1.00 44.65 ? 366 GLY C O   1 
ATOM 1552 N N   . GLY C 1 278 ? 170.740 128.551 139.372 1.00 47.72 ? 367 GLY C N   1 
ATOM 1553 C CA  . GLY C 1 278 ? 170.532 129.823 140.075 1.00 47.72 ? 367 GLY C CA  1 
ATOM 1554 C C   . GLY C 1 278 ? 171.608 130.193 141.099 1.00 47.72 ? 367 GLY C C   1 
ATOM 1555 O O   . GLY C 1 278 ? 171.362 131.013 141.980 1.00 47.72 ? 367 GLY C O   1 
ATOM 1556 N N   . ASN C 1 279 ? 172.779 129.566 141.033 1.00 50.20 ? 368 ASN C N   1 
ATOM 1557 C CA  . ASN C 1 279 ? 173.940 129.882 141.861 1.00 50.20 ? 368 ASN C CA  1 
ATOM 1558 C C   . ASN C 1 279 ? 174.630 131.175 141.427 1.00 50.20 ? 368 ASN C C   1 
ATOM 1559 O O   . ASN C 1 279 ? 174.697 131.493 140.241 1.00 50.20 ? 368 ASN C O   1 
ATOM 1560 C CB  . ASN C 1 279 ? 174.912 128.700 141.824 1.00 50.20 ? 368 ASN C CB  1 
ATOM 1561 C CG  . ASN C 1 279 ? 174.289 127.455 142.406 1.00 50.20 ? 368 ASN C CG  1 
ATOM 1562 O OD1 . ASN C 1 279 ? 173.846 127.438 143.538 1.00 50.20 ? 368 ASN C OD1 1 
ATOM 1563 N ND2 . ASN C 1 279 ? 174.140 126.413 141.640 1.00 50.20 ? 368 ASN C ND2 1 
ATOM 1564 N N   . LYS C 1 280 ? 175.199 131.888 142.397 1.00 51.65 ? 369 LYS C N   1 
ATOM 1565 C CA  . LYS C 1 280 ? 175.892 133.168 142.222 1.00 51.65 ? 369 LYS C CA  1 
ATOM 1566 C C   . LYS C 1 280 ? 177.250 133.132 142.903 1.00 51.65 ? 369 LYS C C   1 
ATOM 1567 O O   . LYS C 1 280 ? 177.355 132.665 144.036 1.00 51.65 ? 369 LYS C O   1 
ATOM 1568 C CB  . LYS C 1 280 ? 175.048 134.307 142.818 1.00 51.65 ? 369 LYS C CB  1 
ATOM 1569 C CG  . LYS C 1 280 ? 173.678 134.481 142.147 1.00 51.65 ? 369 LYS C CG  1 
ATOM 1570 C CD  . LYS C 1 280 ? 172.842 135.585 142.805 1.00 51.65 ? 369 LYS C CD  1 
ATOM 1571 C CE  . LYS C 1 280 ? 173.438 136.987 142.651 1.00 51.65 ? 369 LYS C CE  1 
ATOM 1572 N NZ  . LYS C 1 280 ? 172.489 138.019 143.139 1.00 51.65 ? 369 LYS C NZ  1 
ATOM 1573 N N   . LYS C 1 281 ? 178.270 133.681 142.247 1.00 54.62 ? 370 LYS C N   1 
ATOM 1574 C CA  . LYS C 1 281 ? 179.586 133.962 142.834 1.00 54.62 ? 370 LYS C CA  1 
ATOM 1575 C C   . LYS C 1 281 ? 180.025 135.366 142.433 1.00 54.62 ? 370 LYS C C   1 
ATOM 1576 O O   . LYS C 1 281 ? 180.011 135.698 141.253 1.00 54.62 ? 370 LYS C O   1 
ATOM 1577 C CB  . LYS C 1 281 ? 180.555 132.854 142.398 1.00 54.62 ? 370 LYS C CB  1 
ATOM 1578 C CG  . LYS C 1 281 ? 181.988 133.074 142.905 1.00 54.62 ? 370 LYS C CG  1 
ATOM 1579 C CD  . LYS C 1 281 ? 182.844 131.838 142.591 1.00 54.62 ? 370 LYS C CD  1 
ATOM 1580 C CE  . LYS C 1 281 ? 184.352 132.114 142.663 1.00 54.62 ? 370 LYS C CE  1 
ATOM 1581 N NZ  . LYS C 1 281 ? 184.850 132.301 144.043 1.00 54.62 ? 370 LYS C NZ  1 
ATOM 1582 N N   . ILE C 1 282 ? 180.417 136.191 143.394 1.00 55.60 ? 371 ILE C N   1 
ATOM 1583 C CA  . ILE C 1 282 ? 180.835 137.579 143.158 1.00 55.60 ? 371 ILE C CA  1 
ATOM 1584 C C   . ILE C 1 282 ? 182.198 137.793 143.808 1.00 55.60 ? 371 ILE C C   1 
ATOM 1585 O O   . ILE C 1 282 ? 182.390 137.476 144.977 1.00 55.60 ? 371 ILE C O   1 
ATOM 1586 C CB  . ILE C 1 282 ? 179.783 138.585 143.684 1.00 55.60 ? 371 ILE C CB  1 
ATOM 1587 C CG1 . ILE C 1 282 ? 178.434 138.421 142.952 1.00 55.60 ? 371 ILE C CG1 1 
ATOM 1588 C CG2 . ILE C 1 282 ? 180.289 140.028 143.515 1.00 55.60 ? 371 ILE C CG2 1 
ATOM 1589 C CD1 . ILE C 1 282 ? 177.275 139.193 143.587 1.00 55.60 ? 371 ILE C CD1 1 
ATOM 1590 N N   . GLU C 1 283 ? 183.140 138.353 143.060 1.00 57.98 ? 372 GLU C N   1 
ATOM 1591 C CA  . GLU C 1 283 ? 184.516 138.630 143.480 1.00 57.98 ? 372 GLU C CA  1 
ATOM 1592 C C   . GLU C 1 283 ? 184.927 140.058 143.118 1.00 57.98 ? 372 GLU C C   1 
ATOM 1593 O O   . GLU C 1 283 ? 184.457 140.618 142.130 1.00 57.98 ? 372 GLU C O   1 
ATOM 1594 C CB  . GLU C 1 283 ? 185.476 137.641 142.813 1.00 57.98 ? 372 GLU C CB  1 
ATOM 1595 C CG  . GLU C 1 283 ? 185.158 136.154 143.043 1.00 57.98 ? 372 GLU C CG  1 
ATOM 1596 C CD  . GLU C 1 283 ? 185.376 135.711 144.494 1.00 57.98 ? 372 GLU C CD  1 
ATOM 1597 O OE1 . GLU C 1 283 ? 186.340 136.174 145.140 1.00 57.98 ? 372 GLU C OE1 1 
ATOM 1598 O OE2 . GLU C 1 283 ? 184.632 134.820 144.963 1.00 57.98 ? 372 GLU C OE2 1 
ATOM 1599 N N   . THR C 1 284 ? 185.819 140.678 143.886 1.00 61.09 ? 373 THR C N   1 
ATOM 1600 C CA  . THR C 1 284 ? 186.308 142.042 143.621 1.00 61.09 ? 373 THR C CA  1 
ATOM 1601 C C   . THR C 1 284 ? 187.706 142.215 144.204 1.00 61.09 ? 373 THR C C   1 
ATOM 1602 O O   . THR C 1 284 ? 187.902 142.031 145.400 1.00 61.09 ? 373 THR C O   1 
ATOM 1603 C CB  . THR C 1 284 ? 185.335 143.075 144.210 1.00 61.09 ? 373 THR C CB  1 
ATOM 1604 O OG1 . THR C 1 284 ? 184.180 143.118 143.408 1.00 61.09 ? 373 THR C OG1 1 
ATOM 1605 C CG2 . THR C 1 284 ? 185.855 144.509 144.233 1.00 61.09 ? 373 THR C CG2 1 
ATOM 1606 N N   . HIS C 1 285 ? 188.672 142.575 143.363 1.00 63.04 ? 374 HIS C N   1 
ATOM 1607 C CA  . HIS C 1 285 ? 190.080 142.787 143.712 1.00 63.04 ? 374 HIS C CA  1 
ATOM 1608 C C   . HIS C 1 285 ? 190.493 144.228 143.434 1.00 63.04 ? 374 HIS C C   1 
ATOM 1609 O O   . HIS C 1 285 ? 190.370 144.703 142.305 1.00 63.04 ? 374 HIS C O   1 
ATOM 1610 C CB  . HIS C 1 285 ? 190.948 141.823 142.895 1.00 63.04 ? 374 HIS C CB  1 
ATOM 1611 C CG  . HIS C 1 285 ? 190.723 140.365 143.207 1.00 63.04 ? 374 HIS C CG  1 
ATOM 1612 N ND1 . HIS C 1 285 ? 191.121 139.715 144.374 1.00 63.04 ? 374 HIS C ND1 1 
ATOM 1613 C CD2 . HIS C 1 285 ? 190.034 139.485 142.434 1.00 63.04 ? 374 HIS C CD2 1 
ATOM 1614 C CE1 . HIS C 1 285 ? 190.702 138.448 144.258 1.00 63.04 ? 374 HIS C CE1 1 
ATOM 1615 N NE2 . HIS C 1 285 ? 190.049 138.282 143.100 1.00 63.04 ? 374 HIS C NE2 1 
ATOM 1616 N N   . LYS C 1 286 ? 191.033 144.921 144.437 1.00 66.96 ? 375 LYS C N   1 
ATOM 1617 C CA  . LYS C 1 286 ? 191.389 146.344 144.348 1.00 66.96 ? 375 LYS C CA  1 
ATOM 1618 C C   . LYS C 1 286 ? 192.743 146.608 145.006 1.00 66.96 ? 375 LYS C C   1 
ATOM 1619 O O   . LYS C 1 286 ? 192.956 146.211 146.149 1.00 66.96 ? 375 LYS C O   1 
ATOM 1620 C CB  . LYS C 1 286 ? 190.273 147.141 145.043 1.00 66.96 ? 375 LYS C CB  1 
ATOM 1621 C CG  . LYS C 1 286 ? 190.416 148.657 144.861 1.00 66.96 ? 375 LYS C CG  1 
ATOM 1622 C CD  . LYS C 1 286 ? 189.178 149.406 145.377 1.00 66.96 ? 375 LYS C CD  1 
ATOM 1623 C CE  . LYS C 1 286 ? 187.943 149.199 144.489 1.00 66.96 ? 375 LYS C CE  1 
ATOM 1624 N NZ  . LYS C 1 286 ? 186.754 149.895 145.042 1.00 66.96 ? 375 LYS C NZ  1 
ATOM 1625 N N   . LEU C 1 287 ? 193.624 147.336 144.324 1.00 70.56 ? 376 LEU C N   1 
ATOM 1626 C CA  . LEU C 1 287 ? 194.891 147.843 144.864 1.00 70.56 ? 376 LEU C CA  1 
ATOM 1627 C C   . LEU C 1 287 ? 195.045 149.321 144.482 1.00 70.56 ? 376 LEU C C   1 
ATOM 1628 O O   . LEU C 1 287 ? 194.777 149.693 143.341 1.00 70.56 ? 376 LEU C O   1 
ATOM 1629 C CB  . LEU C 1 287 ? 196.036 146.931 144.378 1.00 70.56 ? 376 LEU C CB  1 
ATOM 1630 C CG  . LEU C 1 287 ? 197.459 147.390 144.742 1.00 70.56 ? 376 LEU C CG  1 
ATOM 1631 C CD1 . LEU C 1 287 ? 197.677 147.507 146.246 1.00 70.56 ? 376 LEU C CD1 1 
ATOM 1632 C CD2 . LEU C 1 287 ? 198.477 146.377 144.221 1.00 70.56 ? 376 LEU C CD2 1 
ATOM 1633 N N   . THR C 1 288 ? 195.405 150.198 145.417 1.00 73.81 ? 377 THR C N   1 
ATOM 1634 C CA  . THR C 1 288 ? 195.506 151.653 145.176 1.00 73.81 ? 377 THR C CA  1 
ATOM 1635 C C   . THR C 1 288 ? 196.718 152.282 145.867 1.00 73.81 ? 377 THR C C   1 
ATOM 1636 O O   . THR C 1 288 ? 197.035 151.934 147.001 1.00 73.81 ? 377 THR C O   1 
ATOM 1637 C CB  . THR C 1 288 ? 194.199 152.349 145.597 1.00 73.81 ? 377 THR C CB  1 
ATOM 1638 O OG1 . THR C 1 288 ? 193.132 151.873 144.807 1.00 73.81 ? 377 THR C OG1 1 
ATOM 1639 C CG2 . THR C 1 288 ? 194.203 153.864 145.405 1.00 73.81 ? 377 THR C CG2 1 
ATOM 1640 N N   . PHE C 1 289 ? 197.363 153.244 145.204 1.00 77.42 ? 378 PHE C N   1 
ATOM 1641 C CA  . PHE C 1 289 ? 198.483 154.046 145.717 1.00 77.42 ? 378 PHE C CA  1 
ATOM 1642 C C   . PHE C 1 289 ? 198.134 155.535 145.793 1.00 77.42 ? 378 PHE C C   1 
ATOM 1643 O O   . PHE C 1 289 ? 197.561 156.102 144.852 1.00 77.42 ? 378 PHE C O   1 
ATOM 1644 C CB  . PHE C 1 289 ? 199.719 153.810 144.844 1.00 77.42 ? 378 PHE C CB  1 
ATOM 1645 C CG  . PHE C 1 289 ? 200.239 152.392 144.920 1.00 77.42 ? 378 PHE C CG  1 
ATOM 1646 C CD1 . PHE C 1 289 ? 199.704 151.398 144.081 1.00 77.42 ? 378 PHE C CD1 1 
ATOM 1647 C CD2 . PHE C 1 289 ? 201.223 152.054 145.866 1.00 77.42 ? 378 PHE C CD2 1 
ATOM 1648 C CE1 . PHE C 1 289 ? 200.145 150.070 144.195 1.00 77.42 ? 378 PHE C CE1 1 
ATOM 1649 C CE2 . PHE C 1 289 ? 201.662 150.726 145.977 1.00 77.42 ? 378 PHE C CE2 1 
ATOM 1650 C CZ  . PHE C 1 289 ? 201.121 149.732 145.144 1.00 77.42 ? 378 PHE C CZ  1 
ATOM 1651 N N   . GLN D 1 218 ? 77.607  137.647 144.747 1.00 79.40 ? 307 GLN D N   1 
ATOM 1652 C CA  . GLN D 1 218 ? 77.978  138.860 144.026 1.00 79.40 ? 307 GLN D CA  1 
ATOM 1653 C C   . GLN D 1 218 ? 79.311  139.428 144.526 1.00 79.40 ? 307 GLN D C   1 
ATOM 1654 O O   . GLN D 1 218 ? 79.479  139.662 145.721 1.00 79.40 ? 307 GLN D O   1 
ATOM 1655 C CB  . GLN D 1 218 ? 76.855  139.903 144.162 1.00 79.40 ? 307 GLN D CB  1 
ATOM 1656 C CG  . GLN D 1 218 ? 77.186  141.230 143.451 1.00 79.40 ? 307 GLN D CG  1 
ATOM 1657 C CD  . GLN D 1 218 ? 76.069  142.270 143.532 1.00 79.40 ? 307 GLN D CD  1 
ATOM 1658 O OE1 . GLN D 1 218 ? 75.114  142.166 144.288 1.00 79.40 ? 307 GLN D OE1 1 
ATOM 1659 N NE2 . GLN D 1 218 ? 76.159  143.337 142.775 1.00 79.40 ? 307 GLN D NE2 1 
ATOM 1660 N N   . ILE D 1 219 ? 80.236  139.716 143.610 1.00 76.56 ? 308 ILE D N   1 
ATOM 1661 C CA  . ILE D 1 219 ? 81.541  140.312 143.913 1.00 76.56 ? 308 ILE D CA  1 
ATOM 1662 C C   . ILE D 1 219 ? 81.760  141.546 143.032 1.00 76.56 ? 308 ILE D C   1 
ATOM 1663 O O   . ILE D 1 219 ? 81.616  141.482 141.814 1.00 76.56 ? 308 ILE D O   1 
ATOM 1664 C CB  . ILE D 1 219 ? 82.668  139.259 143.749 1.00 76.56 ? 308 ILE D CB  1 
ATOM 1665 C CG1 . ILE D 1 219 ? 82.555  138.102 144.770 1.00 76.56 ? 308 ILE D CG1 1 
ATOM 1666 C CG2 . ILE D 1 219 ? 84.055  139.908 143.915 1.00 76.56 ? 308 ILE D CG2 1 
ATOM 1667 C CD1 . ILE D 1 219 ? 81.694  136.913 144.331 1.00 76.56 ? 308 ILE D CD1 1 
ATOM 1668 N N   . VAL D 1 220 ? 82.158  142.660 143.647 1.00 72.40 ? 309 VAL D N   1 
ATOM 1669 C CA  . VAL D 1 220 ? 82.446  143.948 142.996 1.00 72.40 ? 309 VAL D CA  1 
ATOM 1670 C C   . VAL D 1 220 ? 83.884  144.371 143.307 1.00 72.40 ? 309 VAL D C   1 
ATOM 1671 O O   . VAL D 1 220 ? 84.154  145.065 144.285 1.00 72.40 ? 309 VAL D O   1 
ATOM 1672 C CB  . VAL D 1 220 ? 81.404  145.022 143.363 1.00 72.40 ? 309 VAL D CB  1 
ATOM 1673 C CG1 . VAL D 1 220 ? 81.606  146.295 142.534 1.00 72.40 ? 309 VAL D CG1 1 
ATOM 1674 C CG2 . VAL D 1 220 ? 79.978  144.534 143.095 1.00 72.40 ? 309 VAL D CG2 1 
ATOM 1675 N N   . TYR D 1 221 ? 84.829  143.858 142.525 1.00 69.33 ? 310 TYR D N   1 
ATOM 1676 C CA  . TYR D 1 221 ? 86.254  144.147 142.645 1.00 69.33 ? 310 TYR D CA  1 
ATOM 1677 C C   . TYR D 1 221 ? 86.585  145.430 141.866 1.00 69.33 ? 310 TYR D C   1 
ATOM 1678 O O   . TYR D 1 221 ? 86.734  145.408 140.644 1.00 69.33 ? 310 TYR D O   1 
ATOM 1679 C CB  . TYR D 1 221 ? 87.010  142.910 142.141 1.00 69.33 ? 310 TYR D CB  1 
ATOM 1680 C CG  . TYR D 1 221 ? 88.499  142.911 142.409 1.00 69.33 ? 310 TYR D CG  1 
ATOM 1681 C CD1 . TYR D 1 221 ? 89.401  143.479 141.489 1.00 69.33 ? 310 TYR D CD1 1 
ATOM 1682 C CD2 . TYR D 1 221 ? 88.983  142.282 143.569 1.00 69.33 ? 310 TYR D CD2 1 
ATOM 1683 C CE1 . TYR D 1 221 ? 90.785  143.409 141.727 1.00 69.33 ? 310 TYR D CE1 1 
ATOM 1684 C CE2 . TYR D 1 221 ? 90.365  142.189 143.798 1.00 69.33 ? 310 TYR D CE2 1 
ATOM 1685 C CZ  . TYR D 1 221 ? 91.269  142.746 142.874 1.00 69.33 ? 310 TYR D CZ  1 
ATOM 1686 O OH  . TYR D 1 221 ? 92.602  142.618 143.085 1.00 69.33 ? 310 TYR D OH  1 
ATOM 1687 N N   . LYS D 1 222 ? 86.690  146.569 142.557 1.00 65.39 ? 311 LYS D N   1 
ATOM 1688 C CA  . LYS D 1 222 ? 86.785  147.900 141.934 1.00 65.39 ? 311 LYS D CA  1 
ATOM 1689 C C   . LYS D 1 222 ? 87.790  148.826 142.647 1.00 65.39 ? 311 LYS D C   1 
ATOM 1690 O O   . LYS D 1 222 ? 87.427  149.924 143.060 1.00 65.39 ? 311 LYS D O   1 
ATOM 1691 C CB  . LYS D 1 222 ? 85.358  148.483 141.835 1.00 65.39 ? 311 LYS D CB  1 
ATOM 1692 C CG  . LYS D 1 222 ? 85.271  149.634 140.824 1.00 65.39 ? 311 LYS D CG  1 
ATOM 1693 C CD  . LYS D 1 222 ? 83.846  150.160 140.639 1.00 65.39 ? 311 LYS D CD  1 
ATOM 1694 C CE  . LYS D 1 222 ? 83.838  151.257 139.562 1.00 65.39 ? 311 LYS D CE  1 
ATOM 1695 N NZ  . LYS D 1 222 ? 82.477  151.805 139.341 1.00 65.39 ? 311 LYS D NZ  1 
ATOM 1696 N N   . PRO D 1 223 ? 89.063  148.425 142.818 1.00 63.67 ? 312 PRO D N   1 
ATOM 1697 C CA  . PRO D 1 223 ? 90.085  149.315 143.360 1.00 63.67 ? 312 PRO D CA  1 
ATOM 1698 C C   . PRO D 1 223 ? 90.310  150.536 142.452 1.00 63.67 ? 312 PRO D C   1 
ATOM 1699 O O   . PRO D 1 223 ? 90.174  150.430 141.235 1.00 63.67 ? 312 PRO D O   1 
ATOM 1700 C CB  . PRO D 1 223 ? 91.342  148.445 143.481 1.00 63.67 ? 312 PRO D CB  1 
ATOM 1701 C CG  . PRO D 1 223 ? 91.165  147.407 142.383 1.00 63.67 ? 312 PRO D CG  1 
ATOM 1702 C CD  . PRO D 1 223 ? 89.660  147.167 142.392 1.00 63.67 ? 312 PRO D CD  1 
ATOM 1703 N N   . VAL D 1 224 ? 90.700  151.678 143.027 1.00 61.45 ? 313 VAL D N   1 
ATOM 1704 C CA  . VAL D 1 224 ? 91.008  152.919 142.287 1.00 61.45 ? 313 VAL D CA  1 
ATOM 1705 C C   . VAL D 1 224 ? 92.392  153.449 142.667 1.00 61.45 ? 313 VAL D C   1 
ATOM 1706 O O   . VAL D 1 224 ? 92.692  153.611 143.846 1.00 61.45 ? 313 VAL D O   1 
ATOM 1707 C CB  . VAL D 1 224 ? 89.941  154.000 142.543 1.00 61.45 ? 313 VAL D CB  1 
ATOM 1708 C CG1 . VAL D 1 224 ? 90.260  155.328 141.845 1.00 61.45 ? 313 VAL D CG1 1 
ATOM 1709 C CG2 . VAL D 1 224 ? 88.551  153.544 142.092 1.00 61.45 ? 313 VAL D CG2 1 
ATOM 1710 N N   . ASP D 1 225 ? 93.229  153.777 141.684 1.00 58.83 ? 314 ASP D N   1 
ATOM 1711 C CA  . ASP D 1 225 ? 94.560  154.360 141.891 1.00 58.83 ? 314 ASP D CA  1 
ATOM 1712 C C   . ASP D 1 225 ? 94.724  155.699 141.157 1.00 58.83 ? 314 ASP D C   1 
ATOM 1713 O O   . ASP D 1 225 ? 94.556  155.781 139.944 1.00 58.83 ? 314 ASP D O   1 
ATOM 1714 C CB  . ASP D 1 225 ? 95.616  153.333 141.463 1.00 58.83 ? 314 ASP D CB  1 
ATOM 1715 C CG  . ASP D 1 225 ? 97.070  153.811 141.592 1.00 58.83 ? 314 ASP D CG  1 
ATOM 1716 O OD1 . ASP D 1 225 ? 97.339  154.853 142.228 1.00 58.83 ? 314 ASP D OD1 1 
ATOM 1717 O OD2 . ASP D 1 225 ? 97.966  153.112 141.081 1.00 58.83 ? 314 ASP D OD2 1 
ATOM 1718 N N   . LEU D 1 226 ? 95.117  156.733 141.898 1.00 56.80 ? 315 LEU D N   1 
ATOM 1719 C CA  . LEU D 1 226 ? 95.354  158.117 141.477 1.00 56.80 ? 315 LEU D CA  1 
ATOM 1720 C C   . LEU D 1 226 ? 96.767  158.596 141.874 1.00 56.80 ? 315 LEU D C   1 
ATOM 1721 O O   . LEU D 1 226 ? 97.081  159.782 141.779 1.00 56.80 ? 315 LEU D O   1 
ATOM 1722 C CB  . LEU D 1 226 ? 94.257  158.991 142.120 1.00 56.80 ? 315 LEU D CB  1 
ATOM 1723 C CG  . LEU D 1 226 ? 92.836  158.735 141.580 1.00 56.80 ? 315 LEU D CG  1 
ATOM 1724 C CD1 . LEU D 1 226 ? 91.767  159.179 142.570 1.00 56.80 ? 315 LEU D CD1 1 
ATOM 1725 C CD2 . LEU D 1 226 ? 92.622  159.569 140.318 1.00 56.80 ? 315 LEU D CD2 1 
ATOM 1726 N N   . SER D 1 227 ? 97.620  157.689 142.351 1.00 55.49 ? 316 SER D N   1 
ATOM 1727 C CA  . SER D 1 227 ? 98.932  157.982 142.937 1.00 55.49 ? 316 SER D CA  1 
ATOM 1728 C C   . SER D 1 227 ? 99.964  158.567 141.964 1.00 55.49 ? 316 SER D C   1 
ATOM 1729 O O   . SER D 1 227 ? 99.839  158.445 140.746 1.00 55.49 ? 316 SER D O   1 
ATOM 1730 C CB  . SER D 1 227 ? 99.473  156.720 143.615 1.00 55.49 ? 316 SER D CB  1 
ATOM 1731 O OG  . SER D 1 227 ? 99.722  155.684 142.683 1.00 55.49 ? 316 SER D OG  1 
ATOM 1732 N N   . LYS D 1 228 ? 101.009 159.200 142.502 1.00 53.46 ? 317 LYS D N   1 
ATOM 1733 C CA  . LYS D 1 228 ? 102.107 159.812 141.731 1.00 53.46 ? 317 LYS D CA  1 
ATOM 1734 C C   . LYS D 1 228 ? 103.469 159.333 142.257 1.00 53.46 ? 317 LYS D C   1 
ATOM 1735 O O   . LYS D 1 228 ? 103.665 159.276 143.470 1.00 53.46 ? 317 LYS D O   1 
ATOM 1736 C CB  . LYS D 1 228 ? 102.056 161.347 141.853 1.00 53.46 ? 317 LYS D CB  1 
ATOM 1737 C CG  . LYS D 1 228 ? 100.745 162.048 141.468 1.00 53.46 ? 317 LYS D CG  1 
ATOM 1738 C CD  . LYS D 1 228 ? 100.411 161.967 139.974 1.00 53.46 ? 317 LYS D CD  1 
ATOM 1739 C CE  . LYS D 1 228 ? 99.206  162.848 139.601 1.00 53.46 ? 317 LYS D CE  1 
ATOM 1740 N NZ  . LYS D 1 228 ? 97.893  162.227 139.914 1.00 53.46 ? 317 LYS D NZ  1 
ATOM 1741 N N   . VAL D 1 229 ? 104.420 159.055 141.368 1.00 52.45 ? 318 VAL D N   1 
ATOM 1742 C CA  . VAL D 1 229 ? 105.841 158.858 141.704 1.00 52.45 ? 318 VAL D CA  1 
ATOM 1743 C C   . VAL D 1 229 ? 106.690 159.813 140.864 1.00 52.45 ? 318 VAL D C   1 
ATOM 1744 O O   . VAL D 1 229 ? 106.631 159.760 139.641 1.00 52.45 ? 318 VAL D O   1 
ATOM 1745 C CB  . VAL D 1 229 ? 106.276 157.392 141.527 1.00 52.45 ? 318 VAL D CB  1 
ATOM 1746 C CG1 . VAL D 1 229 ? 107.705 157.176 142.034 1.00 52.45 ? 318 VAL D CG1 1 
ATOM 1747 C CG2 . VAL D 1 229 ? 105.376 156.415 142.285 1.00 52.45 ? 318 VAL D CG2 1 
ATOM 1748 N N   . THR D 1 230 ? 107.491 160.681 141.483 1.00 52.09 ? 319 THR D N   1 
ATOM 1749 C CA  . THR D 1 230 ? 108.065 161.860 140.802 1.00 52.09 ? 319 THR D CA  1 
ATOM 1750 C C   . THR D 1 230 ? 109.499 162.132 141.243 1.00 52.09 ? 319 THR D C   1 
ATOM 1751 O O   . THR D 1 230 ? 109.885 161.827 142.369 1.00 52.09 ? 319 THR D O   1 
ATOM 1752 C CB  . THR D 1 230 ? 107.170 163.096 141.047 1.00 52.09 ? 319 THR D CB  1 
ATOM 1753 O OG1 . THR D 1 230 ? 105.915 162.892 140.448 1.00 52.09 ? 319 THR D OG1 1 
ATOM 1754 C CG2 . THR D 1 230 ? 107.691 164.413 140.474 1.00 52.09 ? 319 THR D CG2 1 
ATOM 1755 N N   . SER D 1 231 ? 110.316 162.746 140.389 1.00 49.98 ? 320 SER D N   1 
ATOM 1756 C CA  . SER D 1 231 ? 111.605 163.324 140.796 1.00 49.98 ? 320 SER D CA  1 
ATOM 1757 C C   . SER D 1 231 ? 112.009 164.536 139.975 1.00 49.98 ? 320 SER D C   1 
ATOM 1758 O O   . SER D 1 231 ? 111.709 164.610 138.786 1.00 49.98 ? 320 SER D O   1 
ATOM 1759 C CB  . SER D 1 231 ? 112.729 162.297 140.683 1.00 49.98 ? 320 SER D CB  1 
ATOM 1760 O OG  . SER D 1 231 ? 112.385 161.158 141.428 1.00 49.98 ? 320 SER D OG  1 
ATOM 1761 N N   . LYS D 1 232 ? 112.786 165.422 140.594 1.00 47.86 ? 321 LYS D N   1 
ATOM 1762 C CA  . LYS D 1 232 ? 113.530 166.489 139.924 1.00 47.86 ? 321 LYS D CA  1 
ATOM 1763 C C   . LYS D 1 232 ? 114.993 166.420 140.355 1.00 47.86 ? 321 LYS D C   1 
ATOM 1764 O O   . LYS D 1 232 ? 115.273 166.321 141.547 1.00 47.86 ? 321 LYS D O   1 
ATOM 1765 C CB  . LYS D 1 232 ? 112.908 167.849 140.282 1.00 47.86 ? 321 LYS D CB  1 
ATOM 1766 C CG  . LYS D 1 232 ? 111.477 167.997 139.748 1.00 47.86 ? 321 LYS D CG  1 
ATOM 1767 C CD  . LYS D 1 232 ? 110.923 169.410 139.973 1.00 47.86 ? 321 LYS D CD  1 
ATOM 1768 C CE  . LYS D 1 232 ? 109.503 169.501 139.402 1.00 47.86 ? 321 LYS D CE  1 
ATOM 1769 N NZ  . LYS D 1 232 ? 108.965 170.882 139.463 1.00 47.86 ? 321 LYS D NZ  1 
ATOM 1770 N N   . CYS D 1 233 ? 115.919 166.510 139.409 1.00 47.04 ? 322 CYS D N   1 
ATOM 1771 C CA  . CYS D 1 233 ? 117.357 166.536 139.667 1.00 47.04 ? 322 CYS D CA  1 
ATOM 1772 C C   . CYS D 1 233 ? 118.006 167.663 138.844 1.00 47.04 ? 322 CYS D C   1 
ATOM 1773 O O   . CYS D 1 233 ? 117.830 167.730 137.628 1.00 47.04 ? 322 CYS D O   1 
ATOM 1774 C CB  . CYS D 1 233 ? 117.905 165.135 139.355 1.00 47.04 ? 322 CYS D CB  1 
ATOM 1775 S SG  . CYS D 1 233 ? 119.676 165.021 139.701 1.00 47.04 ? 322 CYS D SG  1 
ATOM 1776 N N   . GLY D 1 234 ? 118.749 168.570 139.477 1.00 45.03 ? 323 GLY D N   1 
ATOM 1777 C CA  . GLY D 1 234 ? 119.231 169.787 138.816 1.00 45.03 ? 323 GLY D CA  1 
ATOM 1778 C C   . GLY D 1 234 ? 120.398 169.565 137.852 1.00 45.03 ? 323 GLY D C   1 
ATOM 1779 O O   . GLY D 1 234 ? 120.500 170.236 136.827 1.00 45.03 ? 323 GLY D O   1 
ATOM 1780 N N   . SER D 1 235 ? 121.274 168.616 138.164 1.00 43.18 ? 324 SER D N   1 
ATOM 1781 C CA  . SER D 1 235 ? 122.405 168.192 137.340 1.00 43.18 ? 324 SER D CA  1 
ATOM 1782 C C   . SER D 1 235 ? 122.929 166.859 137.855 1.00 43.18 ? 324 SER D C   1 
ATOM 1783 O O   . SER D 1 235 ? 123.025 166.677 139.067 1.00 43.18 ? 324 SER D O   1 
ATOM 1784 C CB  . SER D 1 235 ? 123.521 169.233 137.407 1.00 43.18 ? 324 SER D CB  1 
ATOM 1785 O OG  . SER D 1 235 ? 124.588 168.861 136.561 1.00 43.18 ? 324 SER D OG  1 
ATOM 1786 N N   . LEU D 1 236 ? 123.253 165.926 136.962 1.00 41.17 ? 325 LEU D N   1 
ATOM 1787 C CA  . LEU D 1 236 ? 123.693 164.575 137.307 1.00 41.17 ? 325 LEU D CA  1 
ATOM 1788 C C   . LEU D 1 236 ? 124.953 164.203 136.514 1.00 41.17 ? 325 LEU D C   1 
ATOM 1789 O O   . LEU D 1 236 ? 124.932 164.155 135.286 1.00 41.17 ? 325 LEU D O   1 
ATOM 1790 C CB  . LEU D 1 236 ? 122.500 163.619 137.118 1.00 41.17 ? 325 LEU D CB  1 
ATOM 1791 C CG  . LEU D 1 236 ? 122.796 162.126 137.338 1.00 41.17 ? 325 LEU D CG  1 
ATOM 1792 C CD1 . LEU D 1 236 ? 123.407 161.844 138.702 1.00 41.17 ? 325 LEU D CD1 1 
ATOM 1793 C CD2 . LEU D 1 236 ? 121.481 161.347 137.271 1.00 41.17 ? 325 LEU D CD2 1 
ATOM 1794 N N   . GLY D 1 237 ? 126.070 163.951 137.193 1.00 37.60 ? 326 GLY D N   1 
ATOM 1795 C CA  . GLY D 1 237 ? 127.327 163.694 136.487 1.00 37.60 ? 326 GLY D CA  1 
ATOM 1796 C C   . GLY D 1 237 ? 128.592 163.700 137.330 1.00 37.60 ? 326 GLY D C   1 
ATOM 1797 O O   . GLY D 1 237 ? 128.532 163.723 138.550 1.00 37.60 ? 326 GLY D O   1 
ATOM 1798 N N   . ASN D 1 238 ? 129.757 163.691 136.680 1.00 34.69 ? 327 ASN D N   1 
ATOM 1799 C CA  . ASN D 1 238 ? 131.078 163.554 137.310 1.00 34.69 ? 327 ASN D CA  1 
ATOM 1800 C C   . ASN D 1 238 ? 131.185 162.267 138.149 1.00 34.69 ? 327 ASN D C   1 
ATOM 1801 O O   . ASN D 1 238 ? 131.427 162.300 139.355 1.00 34.69 ? 327 ASN D O   1 
ATOM 1802 C CB  . ASN D 1 238 ? 131.465 164.860 138.029 1.00 34.69 ? 327 ASN D CB  1 
ATOM 1803 C CG  . ASN D 1 238 ? 132.914 164.886 138.473 1.00 34.69 ? 327 ASN D CG  1 
ATOM 1804 O OD1 . ASN D 1 238 ? 133.772 164.187 137.960 1.00 34.69 ? 327 ASN D OD1 1 
ATOM 1805 N ND2 . ASN D 1 238 ? 133.243 165.707 139.434 1.00 34.69 ? 327 ASN D ND2 1 
ATOM 1806 N N   . ILE D 1 239 ? 130.923 161.129 137.507 1.00 33.92 ? 328 ILE D N   1 
ATOM 1807 C CA  . ILE D 1 239 ? 130.910 159.794 138.121 1.00 33.92 ? 328 ILE D CA  1 
ATOM 1808 C C   . ILE D 1 239 ? 132.025 158.940 137.508 1.00 33.92 ? 328 ILE D C   1 
ATOM 1809 O O   . ILE D 1 239 ? 132.098 158.798 136.292 1.00 33.92 ? 328 ILE D O   1 
ATOM 1810 C CB  . ILE D 1 239 ? 129.508 159.158 137.984 1.00 33.92 ? 328 ILE D CB  1 
ATOM 1811 C CG1 . ILE D 1 239 ? 128.442 159.947 138.776 1.00 33.92 ? 328 ILE D CG1 1 
ATOM 1812 C CG2 . ILE D 1 239 ? 129.497 157.700 138.469 1.00 33.92 ? 328 ILE D CG2 1 
ATOM 1813 C CD1 . ILE D 1 239 ? 127.048 159.869 138.155 1.00 33.92 ? 328 ILE D CD1 1 
ATOM 1814 N N   . HIS D 1 240 ? 132.893 158.361 138.333 1.00 32.69 ? 329 HIS D N   1 
ATOM 1815 C CA  . HIS D 1 240 ? 134.042 157.553 137.908 1.00 32.69 ? 329 HIS D CA  1 
ATOM 1816 C C   . HIS D 1 240 ? 133.960 156.152 138.499 1.00 32.69 ? 329 HIS D C   1 
ATOM 1817 O O   . HIS D 1 240 ? 133.988 156.007 139.715 1.00 32.69 ? 329 HIS D O   1 
ATOM 1818 C CB  . HIS D 1 240 ? 135.339 158.242 138.351 1.00 32.69 ? 329 HIS D CB  1 
ATOM 1819 C CG  . HIS D 1 240 ? 135.503 159.647 137.835 1.00 32.69 ? 329 HIS D CG  1 
ATOM 1820 N ND1 . HIS D 1 240 ? 136.134 160.011 136.647 1.00 32.69 ? 329 HIS D ND1 1 
ATOM 1821 C CD2 . HIS D 1 240 ? 134.955 160.758 138.397 1.00 32.69 ? 329 HIS D CD2 1 
ATOM 1822 C CE1 . HIS D 1 240 ? 135.960 161.335 136.530 1.00 32.69 ? 329 HIS D CE1 1 
ATOM 1823 N NE2 . HIS D 1 240 ? 135.253 161.807 137.566 1.00 32.69 ? 329 HIS D NE2 1 
ATOM 1824 N N   . HIS D 1 241 ? 133.915 155.110 137.675 1.00 32.07 ? 330 HIS D N   1 
ATOM 1825 C CA  . HIS D 1 241 ? 133.949 153.717 138.124 1.00 32.07 ? 330 HIS D CA  1 
ATOM 1826 C C   . HIS D 1 241 ? 135.172 153.012 137.533 1.00 32.07 ? 330 HIS D C   1 
ATOM 1827 O O   . HIS D 1 241 ? 135.279 152.846 136.321 1.00 32.07 ? 330 HIS D O   1 
ATOM 1828 C CB  . HIS D 1 241 ? 132.622 153.047 137.757 1.00 32.07 ? 330 HIS D CB  1 
ATOM 1829 C CG  . HIS D 1 241 ? 132.435 151.626 138.231 1.00 32.07 ? 330 HIS D CG  1 
ATOM 1830 N ND1 . HIS D 1 241 ? 131.462 150.778 137.775 1.00 32.07 ? 330 HIS D ND1 1 
ATOM 1831 C CD2 . HIS D 1 241 ? 133.062 150.978 139.259 1.00 32.07 ? 330 HIS D CD2 1 
ATOM 1832 C CE1 . HIS D 1 241 ? 131.518 149.635 138.468 1.00 32.07 ? 330 HIS D CE1 1 
ATOM 1833 N NE2 . HIS D 1 241 ? 132.469 149.720 139.403 1.00 32.07 ? 330 HIS D NE2 1 
ATOM 1834 N N   . LYS D 1 242 ? 136.112 152.603 138.385 1.00 31.44 ? 331 LYS D N   1 
ATOM 1835 C CA  . LYS D 1 242 ? 137.467 152.175 138.002 1.00 31.44 ? 331 LYS D CA  1 
ATOM 1836 C C   . LYS D 1 242 ? 137.933 150.903 138.738 1.00 31.44 ? 331 LYS D C   1 
ATOM 1837 O O   . LYS D 1 242 ? 138.702 151.001 139.690 1.00 31.44 ? 331 LYS D O   1 
ATOM 1838 C CB  . LYS D 1 242 ? 138.410 153.372 138.239 1.00 31.44 ? 331 LYS D CB  1 
ATOM 1839 C CG  . LYS D 1 242 ? 138.242 154.500 137.213 1.00 31.44 ? 331 LYS D CG  1 
ATOM 1840 C CD  . LYS D 1 242 ? 138.917 155.815 137.615 1.00 31.44 ? 331 LYS D CD  1 
ATOM 1841 C CE  . LYS D 1 242 ? 140.446 155.713 137.651 1.00 31.44 ? 331 LYS D CE  1 
ATOM 1842 N NZ  . LYS D 1 242 ? 141.059 157.040 137.902 1.00 31.44 ? 331 LYS D NZ  1 
ATOM 1843 N N   . PRO D 1 243 ? 137.460 149.702 138.359 1.00 31.12 ? 332 PRO D N   1 
ATOM 1844 C CA  . PRO D 1 243 ? 137.885 148.441 138.983 1.00 31.12 ? 332 PRO D CA  1 
ATOM 1845 C C   . PRO D 1 243 ? 139.281 147.940 138.597 1.00 31.12 ? 332 PRO D C   1 
ATOM 1846 O O   . PRO D 1 243 ? 139.667 147.970 137.435 1.00 31.12 ? 332 PRO D O   1 
ATOM 1847 C CB  . PRO D 1 243 ? 136.804 147.413 138.634 1.00 31.12 ? 332 PRO D CB  1 
ATOM 1848 C CG  . PRO D 1 243 ? 135.615 148.261 138.204 1.00 31.12 ? 332 PRO D CG  1 
ATOM 1849 C CD  . PRO D 1 243 ? 136.273 149.464 137.558 1.00 31.12 ? 332 PRO D CD  1 
ATOM 1850 N N   . GLY D 1 244 ? 140.006 147.380 139.565 1.00 30.86 ? 333 GLY D N   1 
ATOM 1851 C CA  . GLY D 1 244 ? 141.373 146.863 139.447 1.00 30.86 ? 333 GLY D CA  1 
ATOM 1852 C C   . GLY D 1 244 ? 141.497 145.359 139.211 1.00 30.86 ? 333 GLY D C   1 
ATOM 1853 O O   . GLY D 1 244 ? 142.308 144.704 139.858 1.00 30.86 ? 333 GLY D O   1 
ATOM 1854 N N   . GLY D 1 245 ? 140.720 144.794 138.291 1.00 30.37 ? 334 GLY D N   1 
ATOM 1855 C CA  . GLY D 1 245 ? 140.828 143.386 137.893 1.00 30.37 ? 334 GLY D CA  1 
ATOM 1856 C C   . GLY D 1 245 ? 140.310 142.400 138.942 1.00 30.37 ? 334 GLY D C   1 
ATOM 1857 O O   . GLY D 1 245 ? 139.299 142.651 139.589 1.00 30.37 ? 334 GLY D O   1 
ATOM 1858 N N   . GLY D 1 246 ? 140.997 141.273 139.111 1.00 30.75 ? 335 GLY D N   1 
ATOM 1859 C CA  . GLY D 1 246 ? 140.645 140.213 140.058 1.00 30.75 ? 335 GLY D CA  1 
ATOM 1860 C C   . GLY D 1 246 ? 140.672 138.820 139.434 1.00 30.75 ? 335 GLY D C   1 
ATOM 1861 O O   . GLY D 1 246 ? 140.924 138.669 138.241 1.00 30.75 ? 335 GLY D O   1 
ATOM 1862 N N   . GLN D 1 247 ? 140.424 137.783 140.228 1.00 31.95 ? 336 GLN D N   1 
ATOM 1863 C CA  . GLN D 1 247 ? 140.477 136.404 139.744 1.00 31.95 ? 336 GLN D CA  1 
ATOM 1864 C C   . GLN D 1 247 ? 139.418 135.479 140.358 1.00 31.95 ? 336 GLN D C   1 
ATOM 1865 O O   . GLN D 1 247 ? 139.192 135.505 141.564 1.00 31.95 ? 336 GLN D O   1 
ATOM 1866 C CB  . GLN D 1 247 ? 141.900 135.904 139.971 1.00 31.95 ? 336 GLN D CB  1 
ATOM 1867 C CG  . GLN D 1 247 ? 142.188 134.584 139.263 1.00 31.95 ? 336 GLN D CG  1 
ATOM 1868 C CD  . GLN D 1 247 ? 143.688 134.415 139.159 1.00 31.95 ? 336 GLN D CD  1 
ATOM 1869 O OE1 . GLN D 1 247 ? 144.316 134.026 140.117 1.00 31.95 ? 336 GLN D OE1 1 
ATOM 1870 N NE2 . GLN D 1 247 ? 144.315 134.685 138.041 1.00 31.95 ? 336 GLN D NE2 1 
ATOM 1871 N N   . VAL D 1 248 ? 138.796 134.627 139.542 1.00 34.06 ? 337 VAL D N   1 
ATOM 1872 C CA  . VAL D 1 248 ? 137.711 133.715 139.946 1.00 34.06 ? 337 VAL D CA  1 
ATOM 1873 C C   . VAL D 1 248 ? 137.955 132.305 139.414 1.00 34.06 ? 337 VAL D C   1 
ATOM 1874 O O   . VAL D 1 248 ? 138.250 132.134 138.237 1.00 34.06 ? 337 VAL D O   1 
ATOM 1875 C CB  . VAL D 1 248 ? 136.343 134.251 139.467 1.00 34.06 ? 337 VAL D CB  1 
ATOM 1876 C CG1 . VAL D 1 248 ? 135.176 133.342 139.854 1.00 34.06 ? 337 VAL D CG1 1 
ATOM 1877 C CG2 . VAL D 1 248 ? 136.052 135.639 140.040 1.00 34.06 ? 337 VAL D CG2 1 
ATOM 1878 N N   . GLU D 1 249 ? 137.775 131.283 140.247 1.00 37.66 ? 338 GLU D N   1 
ATOM 1879 C CA  . GLU D 1 249 ? 137.858 129.875 139.853 1.00 37.66 ? 338 GLU D CA  1 
ATOM 1880 C C   . GLU D 1 249 ? 136.700 129.049 140.420 1.00 37.66 ? 338 GLU D C   1 
ATOM 1881 O O   . GLU D 1 249 ? 136.403 129.134 141.608 1.00 37.66 ? 338 GLU D O   1 
ATOM 1882 C CB  . GLU D 1 249 ? 139.212 129.309 140.291 1.00 37.66 ? 338 GLU D CB  1 
ATOM 1883 C CG  . GLU D 1 249 ? 139.384 127.823 139.948 1.00 37.66 ? 338 GLU D CG  1 
ATOM 1884 C CD  . GLU D 1 249 ? 140.796 127.292 140.245 1.00 37.66 ? 338 GLU D CD  1 
ATOM 1885 O OE1 . GLU D 1 249 ? 141.749 128.090 140.377 1.00 37.66 ? 338 GLU D OE1 1 
ATOM 1886 O OE2 . GLU D 1 249 ? 140.964 126.056 140.335 1.00 37.66 ? 338 GLU D OE2 1 
ATOM 1887 N N   . VAL D 1 250 ? 136.072 128.205 139.596 1.00 39.59 ? 339 VAL D N   1 
ATOM 1888 C CA  . VAL D 1 250 ? 134.978 127.315 140.019 1.00 39.59 ? 339 VAL D CA  1 
ATOM 1889 C C   . VAL D 1 250 ? 135.170 125.893 139.482 1.00 39.59 ? 339 VAL D C   1 
ATOM 1890 O O   . VAL D 1 250 ? 135.468 125.709 138.306 1.00 39.59 ? 339 VAL D O   1 
ATOM 1891 C CB  . VAL D 1 250 ? 133.600 127.881 139.617 1.00 39.59 ? 339 VAL D CB  1 
ATOM 1892 C CG1 . VAL D 1 250 ? 132.474 127.017 140.188 1.00 39.59 ? 339 VAL D CG1 1 
ATOM 1893 C CG2 . VAL D 1 250 ? 133.373 129.318 140.101 1.00 39.59 ? 339 VAL D CG2 1 
ATOM 1894 N N   . LYS D 1 251 ? 134.946 124.870 140.311 1.00 44.07 ? 340 LYS D N   1 
ATOM 1895 C CA  . LYS D 1 251 ? 135.058 123.449 139.942 1.00 44.07 ? 340 LYS D CA  1 
ATOM 1896 C C   . LYS D 1 251 ? 133.817 122.648 140.360 1.00 44.07 ? 340 LYS D C   1 
ATOM 1897 O O   . LYS D 1 251 ? 133.347 122.800 141.481 1.00 44.07 ? 340 LYS D O   1 
ATOM 1898 C CB  . LYS D 1 251 ? 136.354 122.905 140.562 1.00 44.07 ? 340 LYS D CB  1 
ATOM 1899 C CG  . LYS D 1 251 ? 136.676 121.476 140.108 1.00 44.07 ? 340 LYS D CG  1 
ATOM 1900 C CD  . LYS D 1 251 ? 138.016 120.947 140.642 1.00 44.07 ? 340 LYS D CD  1 
ATOM 1901 C CE  . LYS D 1 251 ? 139.221 121.724 140.092 1.00 44.07 ? 340 LYS D CE  1 
ATOM 1902 N NZ  . LYS D 1 251 ? 140.508 121.103 140.486 1.00 44.07 ? 340 LYS D NZ  1 
ATOM 1903 N N   . SER D 1 252 ? 133.322 121.776 139.482 1.00 48.72 ? 341 SER D N   1 
ATOM 1904 C CA  . SER D 1 252 ? 132.160 120.883 139.667 1.00 48.72 ? 341 SER D CA  1 
ATOM 1905 C C   . SER D 1 252 ? 132.381 119.530 138.982 1.00 48.72 ? 341 SER D C   1 
ATOM 1906 O O   . SER D 1 252 ? 133.124 119.461 138.009 1.00 48.72 ? 341 SER D O   1 
ATOM 1907 C CB  . SER D 1 252 ? 130.897 121.500 139.057 1.00 48.72 ? 341 SER D CB  1 
ATOM 1908 O OG  . SER D 1 252 ? 130.497 122.655 139.755 1.00 48.72 ? 341 SER D OG  1 
ATOM 1909 N N   . GLU D 1 253 ? 131.701 118.457 139.397 1.00 51.37 ? 342 GLU D N   1 
ATOM 1910 C CA  . GLU D 1 253 ? 131.555 117.277 138.531 1.00 51.37 ? 342 GLU D CA  1 
ATOM 1911 C C   . GLU D 1 253 ? 130.280 117.416 137.688 1.00 51.37 ? 342 GLU D C   1 
ATOM 1912 O O   . GLU D 1 253 ? 130.347 117.370 136.464 1.00 51.37 ? 342 GLU D O   1 
ATOM 1913 C CB  . GLU D 1 253 ? 131.492 115.960 139.329 1.00 51.37 ? 342 GLU D CB  1 
ATOM 1914 C CG  . GLU D 1 253 ? 132.609 115.773 140.368 1.00 51.37 ? 342 GLU D CG  1 
ATOM 1915 C CD  . GLU D 1 253 ? 134.022 115.658 139.779 1.00 51.37 ? 342 GLU D CD  1 
ATOM 1916 O OE1 . GLU D 1 253 ? 134.173 115.188 138.631 1.00 51.37 ? 342 GLU D OE1 1 
ATOM 1917 O OE2 . GLU D 1 253 ? 135.002 116.016 140.470 1.00 51.37 ? 342 GLU D OE2 1 
ATOM 1918 N N   . LYS D 1 254 ? 129.116 117.669 138.302 1.00 50.94 ? 343 LYS D N   1 
ATOM 1919 C CA  . LYS D 1 254 ? 127.817 117.593 137.602 1.00 50.94 ? 343 LYS D CA  1 
ATOM 1920 C C   . LYS D 1 254 ? 126.872 118.730 137.974 1.00 50.94 ? 343 LYS D C   1 
ATOM 1921 O O   . LYS D 1 254 ? 126.729 119.033 139.156 1.00 50.94 ? 343 LYS D O   1 
ATOM 1922 C CB  . LYS D 1 254 ? 127.134 116.250 137.924 1.00 50.94 ? 343 LYS D CB  1 
ATOM 1923 C CG  . LYS D 1 254 ? 127.960 115.035 137.487 1.00 50.94 ? 343 LYS D CG  1 
ATOM 1924 C CD  . LYS D 1 254 ? 127.154 113.734 137.570 1.00 50.94 ? 343 LYS D CD  1 
ATOM 1925 C CE  . LYS D 1 254 ? 128.036 112.556 137.135 1.00 50.94 ? 343 LYS D CE  1 
ATOM 1926 N NZ  . LYS D 1 254 ? 127.272 111.290 137.063 1.00 50.94 ? 343 LYS D NZ  1 
ATOM 1927 N N   . LEU D 1 255 ? 126.183 119.304 136.987 1.00 50.12 ? 344 LEU D N   1 
ATOM 1928 C CA  . LEU D 1 255 ? 125.085 120.261 137.174 1.00 50.12 ? 344 LEU D CA  1 
ATOM 1929 C C   . LEU D 1 255 ? 123.785 119.708 136.580 1.00 50.12 ? 344 LEU D C   1 
ATOM 1930 O O   . LEU D 1 255 ? 123.771 119.246 135.441 1.00 50.12 ? 344 LEU D O   1 
ATOM 1931 C CB  . LEU D 1 255 ? 125.400 121.625 136.529 1.00 50.12 ? 344 LEU D CB  1 
ATOM 1932 C CG  . LEU D 1 255 ? 126.741 122.278 136.895 1.00 50.12 ? 344 LEU D CG  1 
ATOM 1933 C CD1 . LEU D 1 255 ? 126.844 123.657 136.252 1.00 50.12 ? 344 LEU D CD1 1 
ATOM 1934 C CD2 . LEU D 1 255 ? 126.874 122.508 138.387 1.00 50.12 ? 344 LEU D CD2 1 
ATOM 1935 N N   . ASP D 1 256 ? 122.683 119.798 137.317 1.00 49.93 ? 345 ASP D N   1 
ATOM 1936 C CA  . ASP D 1 256 ? 121.383 119.239 136.925 1.00 49.93 ? 345 ASP D CA  1 
ATOM 1937 C C   . ASP D 1 256 ? 120.235 120.165 137.351 1.00 49.93 ? 345 ASP D C   1 
ATOM 1938 O O   . ASP D 1 256 ? 119.851 120.202 138.516 1.00 49.93 ? 345 ASP D O   1 
ATOM 1939 C CB  . ASP D 1 256 ? 121.291 117.825 137.518 1.00 49.93 ? 345 ASP D CB  1 
ATOM 1940 C CG  . ASP D 1 256 ? 120.055 117.026 137.094 1.00 49.93 ? 345 ASP D CG  1 
ATOM 1941 O OD1 . ASP D 1 256 ? 119.191 117.549 136.365 1.00 49.93 ? 345 ASP D OD1 1 
ATOM 1942 O OD2 . ASP D 1 256 ? 119.972 115.834 137.467 1.00 49.93 ? 345 ASP D OD2 1 
ATOM 1943 N N   . PHE D 1 257 ? 119.741 120.989 136.426 1.00 48.05 ? 346 PHE D N   1 
ATOM 1944 C CA  . PHE D 1 257 ? 118.763 122.051 136.697 1.00 48.05 ? 346 PHE D CA  1 
ATOM 1945 C C   . PHE D 1 257 ? 117.414 121.767 136.033 1.00 48.05 ? 346 PHE D C   1 
ATOM 1946 O O   . PHE D 1 257 ? 117.362 121.546 134.824 1.00 48.05 ? 346 PHE D O   1 
ATOM 1947 C CB  . PHE D 1 257 ? 119.307 123.415 136.245 1.00 48.05 ? 346 PHE D CB  1 
ATOM 1948 C CG  . PHE D 1 257 ? 120.623 123.896 136.841 1.00 48.05 ? 346 PHE D CG  1 
ATOM 1949 C CD1 . PHE D 1 257 ? 121.172 123.322 138.002 1.00 48.05 ? 346 PHE D CD1 1 
ATOM 1950 C CD2 . PHE D 1 257 ? 121.325 124.932 136.201 1.00 48.05 ? 346 PHE D CD2 1 
ATOM 1951 C CE1 . PHE D 1 257 ? 122.431 123.718 138.470 1.00 48.05 ? 346 PHE D CE1 1 
ATOM 1952 C CE2 . PHE D 1 257 ? 122.579 125.345 136.680 1.00 48.05 ? 346 PHE D CE2 1 
ATOM 1953 C CZ  . PHE D 1 257 ? 123.140 124.727 137.807 1.00 48.05 ? 346 PHE D CZ  1 
ATOM 1954 N N   . LYS D 1 258 ? 116.315 121.829 136.794 1.00 48.31 ? 347 LYS D N   1 
ATOM 1955 C CA  . LYS D 1 258 ? 114.950 121.596 136.301 1.00 48.31 ? 347 LYS D CA  1 
ATOM 1956 C C   . LYS D 1 258 ? 113.983 122.681 136.755 1.00 48.31 ? 347 LYS D C   1 
ATOM 1957 O O   . LYS D 1 258 ? 113.997 123.053 137.920 1.00 48.31 ? 347 LYS D O   1 
ATOM 1958 C CB  . LYS D 1 258 ? 114.420 120.228 136.772 1.00 48.31 ? 347 LYS D CB  1 
ATOM 1959 C CG  . LYS D 1 258 ? 115.294 119.051 136.329 1.00 48.31 ? 347 LYS D CG  1 
ATOM 1960 C CD  . LYS D 1 258 ? 114.661 117.711 136.711 1.00 48.31 ? 347 LYS D CD  1 
ATOM 1961 C CE  . LYS D 1 258 ? 115.615 116.572 136.330 1.00 48.31 ? 347 LYS D CE  1 
ATOM 1962 N NZ  . LYS D 1 258 ? 114.988 115.238 136.498 1.00 48.31 ? 347 LYS D NZ  1 
ATOM 1963 N N   . ASP D 1 259 ? 113.042 123.058 135.897 1.00 45.92 ? 348 ASP D N   1 
ATOM 1964 C CA  . ASP D 1 259 ? 111.813 123.773 136.262 1.00 45.92 ? 348 ASP D CA  1 
ATOM 1965 C C   . ASP D 1 259 ? 112.021 125.135 136.955 1.00 45.92 ? 348 ASP D C   1 
ATOM 1966 O O   . ASP D 1 259 ? 112.033 125.240 138.180 1.00 45.92 ? 348 ASP D O   1 
ATOM 1967 C CB  . ASP D 1 259 ? 110.924 122.818 137.073 1.00 45.92 ? 348 ASP D CB  1 
ATOM 1968 C CG  . ASP D 1 259 ? 109.585 123.436 137.459 1.00 45.92 ? 348 ASP D CG  1 
ATOM 1969 O OD1 . ASP D 1 259 ? 109.134 124.412 136.828 1.00 45.92 ? 348 ASP D OD1 1 
ATOM 1970 O OD2 . ASP D 1 259 ? 108.946 122.939 138.409 1.00 45.92 ? 348 ASP D OD2 1 
ATOM 1971 N N   . ARG D 1 260 ? 112.121 126.209 136.161 1.00 44.03 ? 349 ARG D N   1 
ATOM 1972 C CA  . ARG D 1 260 ? 112.263 127.602 136.638 1.00 44.03 ? 349 ARG D CA  1 
ATOM 1973 C C   . ARG D 1 260 ? 113.519 127.804 137.490 1.00 44.03 ? 349 ARG D C   1 
ATOM 1974 O O   . ARG D 1 260 ? 113.448 128.187 138.653 1.00 44.03 ? 349 ARG D O   1 
ATOM 1975 C CB  . ARG D 1 260 ? 110.968 128.091 137.315 1.00 44.03 ? 349 ARG D CB  1 
ATOM 1976 C CG  . ARG D 1 260 ? 109.794 128.193 136.329 1.00 44.03 ? 349 ARG D CG  1 
ATOM 1977 C CD  . ARG D 1 260 ? 108.447 128.198 137.057 1.00 44.03 ? 349 ARG D CD  1 
ATOM 1978 N NE  . ARG D 1 260 ? 108.171 126.857 137.603 1.00 44.03 ? 349 ARG D NE  1 
ATOM 1979 C CZ  . ARG D 1 260 ? 107.513 126.539 138.693 1.00 44.03 ? 349 ARG D CZ  1 
ATOM 1980 N NH1 . ARG D 1 260 ? 106.740 127.370 139.320 1.00 44.03 ? 349 ARG D NH1 1 
ATOM 1981 N NH2 . ARG D 1 260 ? 107.650 125.350 139.175 1.00 44.03 ? 349 ARG D NH2 1 
ATOM 1982 N N   . VAL D 1 261 ? 114.682 127.531 136.909 1.00 42.60 ? 350 VAL D N   1 
ATOM 1983 C CA  . VAL D 1 261 ? 115.991 127.801 137.528 1.00 42.60 ? 350 VAL D CA  1 
ATOM 1984 C C   . VAL D 1 261 ? 116.635 129.017 136.878 1.00 42.60 ? 350 VAL D C   1 
ATOM 1985 O O   . VAL D 1 261 ? 116.760 129.063 135.660 1.00 42.60 ? 350 VAL D O   1 
ATOM 1986 C CB  . VAL D 1 261 ? 116.920 126.579 137.454 1.00 42.60 ? 350 VAL D CB  1 
ATOM 1987 C CG1 . VAL D 1 261 ? 118.312 126.869 138.022 1.00 42.60 ? 350 VAL D CG1 1 
ATOM 1988 C CG2 . VAL D 1 261 ? 116.324 125.408 138.229 1.00 42.60 ? 350 VAL D CG2 1 
ATOM 1989 N N   . GLN D 1 262 ? 117.089 129.978 137.675 1.00 39.71 ? 351 GLN D N   1 
ATOM 1990 C CA  . GLN D 1 262 ? 117.943 131.076 137.228 1.00 39.71 ? 351 GLN D CA  1 
ATOM 1991 C C   . GLN D 1 262 ? 119.311 130.946 137.911 1.00 39.71 ? 351 GLN D C   1 
ATOM 1992 O O   . GLN D 1 262 ? 119.395 130.975 139.135 1.00 39.71 ? 351 GLN D O   1 
ATOM 1993 C CB  . GLN D 1 262 ? 117.219 132.391 137.523 1.00 39.71 ? 351 GLN D CB  1 
ATOM 1994 C CG  . GLN D 1 262 ? 117.991 133.624 137.046 1.00 39.71 ? 351 GLN D CG  1 
ATOM 1995 C CD  . GLN D 1 262 ? 117.275 134.939 137.350 1.00 39.71 ? 351 GLN D CD  1 
ATOM 1996 O OE1 . GLN D 1 262 ? 117.898 135.951 137.635 1.00 39.71 ? 351 GLN D OE1 1 
ATOM 1997 N NE2 . GLN D 1 262 ? 115.964 134.991 137.344 1.00 39.71 ? 351 GLN D NE2 1 
ATOM 1998 N N   . SER D 1 263 ? 120.386 130.781 137.145 1.00 38.51 ? 352 SER D N   1 
ATOM 1999 C CA  . SER D 1 263 ? 121.707 130.417 137.672 1.00 38.51 ? 352 SER D CA  1 
ATOM 2000 C C   . SER D 1 263 ? 122.831 131.269 137.084 1.00 38.51 ? 352 SER D C   1 
ATOM 2001 O O   . SER D 1 263 ? 122.839 131.553 135.890 1.00 38.51 ? 352 SER D O   1 
ATOM 2002 C CB  . SER D 1 263 ? 121.957 128.932 137.418 1.00 38.51 ? 352 SER D CB  1 
ATOM 2003 O OG  . SER D 1 263 ? 123.178 128.535 137.998 1.00 38.51 ? 352 SER D OG  1 
ATOM 2004 N N   . LYS D 1 264 ? 123.802 131.652 137.915 1.00 36.97 ? 353 LYS D N   1 
ATOM 2005 C CA  . LYS D 1 264 ? 125.032 132.352 137.524 1.00 36.97 ? 353 LYS D CA  1 
ATOM 2006 C C   . LYS D 1 264 ? 126.241 131.693 138.190 1.00 36.97 ? 353 LYS D C   1 
ATOM 2007 O O   . LYS D 1 264 ? 126.301 131.646 139.413 1.00 36.97 ? 353 LYS D O   1 
ATOM 2008 C CB  . LYS D 1 264 ? 124.859 133.836 137.882 1.00 36.97 ? 353 LYS D CB  1 
ATOM 2009 C CG  . LYS D 1 264 ? 125.965 134.725 137.311 1.00 36.97 ? 353 LYS D CG  1 
ATOM 2010 C CD  . LYS D 1 264 ? 125.785 136.188 137.745 1.00 36.97 ? 353 LYS D CD  1 
ATOM 2011 C CE  . LYS D 1 264 ? 126.843 137.042 137.042 1.00 36.97 ? 353 LYS D CE  1 
ATOM 2012 N NZ  . LYS D 1 264 ? 126.903 138.452 137.507 1.00 36.97 ? 353 LYS D NZ  1 
ATOM 2013 N N   . ILE D 1 265 ? 127.189 131.172 137.413 1.00 37.68 ? 354 ILE D N   1 
ATOM 2014 C CA  . ILE D 1 265 ? 128.370 130.446 137.913 1.00 37.68 ? 354 ILE D CA  1 
ATOM 2015 C C   . ILE D 1 265 ? 129.654 131.049 137.338 1.00 37.68 ? 354 ILE D C   1 
ATOM 2016 O O   . ILE D 1 265 ? 129.826 131.071 136.126 1.00 37.68 ? 354 ILE D O   1 
ATOM 2017 C CB  . ILE D 1 265 ? 128.260 128.931 137.612 1.00 37.68 ? 354 ILE D CB  1 
ATOM 2018 C CG1 . ILE D 1 265 ? 126.976 128.331 138.227 1.00 37.68 ? 354 ILE D CG1 1 
ATOM 2019 C CG2 . ILE D 1 265 ? 129.499 128.180 138.120 1.00 37.68 ? 354 ILE D CG2 1 
ATOM 2020 C CD1 . ILE D 1 265 ? 126.759 126.847 137.932 1.00 37.68 ? 354 ILE D CD1 1 
ATOM 2021 N N   . GLY D 1 266 ? 130.585 131.487 138.185 1.00 36.70 ? 355 GLY D N   1 
ATOM 2022 C CA  . GLY D 1 266 ? 131.885 132.014 137.767 1.00 36.70 ? 355 GLY D CA  1 
ATOM 2023 C C   . GLY D 1 266 ? 131.798 133.329 136.987 1.00 36.70 ? 355 GLY D C   1 
ATOM 2024 O O   . GLY D 1 266 ? 131.818 133.321 135.762 1.00 36.70 ? 355 GLY D O   1 
ATOM 2025 N N   . SER D 1 267 ? 131.733 134.474 137.661 1.00 35.60 ? 356 SER D N   1 
ATOM 2026 C CA  . SER D 1 267 ? 131.670 135.788 136.999 1.00 35.60 ? 356 SER D CA  1 
ATOM 2027 C C   . SER D 1 267 ? 132.619 136.829 137.566 1.00 35.60 ? 356 SER D C   1 
ATOM 2028 O O   . SER D 1 267 ? 132.938 136.818 138.750 1.00 35.60 ? 356 SER D O   1 
ATOM 2029 C CB  . SER D 1 267 ? 130.254 136.348 137.007 1.00 35.60 ? 356 SER D CB  1 
ATOM 2030 O OG  . SER D 1 267 ? 129.854 136.749 138.304 1.00 35.60 ? 356 SER D OG  1 
ATOM 2031 N N   . LEU D 1 268 ? 133.002 137.779 136.723 1.00 34.82 ? 357 LEU D N   1 
ATOM 2032 C CA  . LEU D 1 268 ? 133.701 139.000 137.106 1.00 34.82 ? 357 LEU D CA  1 
ATOM 2033 C C   . LEU D 1 268 ? 133.069 140.161 136.328 1.00 34.82 ? 357 LEU D C   1 
ATOM 2034 O O   . LEU D 1 268 ? 133.602 140.610 135.319 1.00 34.82 ? 357 LEU D O   1 
ATOM 2035 C CB  . LEU D 1 268 ? 135.211 138.764 136.890 1.00 34.82 ? 357 LEU D CB  1 
ATOM 2036 C CG  . LEU D 1 268 ? 136.172 139.752 137.576 1.00 34.82 ? 357 LEU D CG  1 
ATOM 2037 C CD1 . LEU D 1 268 ? 137.564 139.126 137.661 1.00 34.82 ? 357 LEU D CD1 1 
ATOM 2038 C CD2 . LEU D 1 268 ? 136.328 141.087 136.858 1.00 34.82 ? 357 LEU D CD2 1 
ATOM 2039 N N   . ASP D 1 269 ? 131.884 140.597 136.763 1.00 35.60 ? 358 ASP D N   1 
ATOM 2040 C CA  . ASP D 1 269 ? 131.031 141.530 136.018 1.00 35.60 ? 358 ASP D CA  1 
ATOM 2041 C C   . ASP D 1 269 ? 130.991 142.944 136.641 1.00 35.60 ? 358 ASP D C   1 
ATOM 2042 O O   . ASP D 1 269 ? 130.771 143.099 137.837 1.00 35.60 ? 358 ASP D O   1 
ATOM 2043 C CB  . ASP D 1 269 ? 129.610 140.956 135.874 1.00 35.60 ? 358 ASP D CB  1 
ATOM 2044 C CG  . ASP D 1 269 ? 129.460 139.630 135.099 1.00 35.60 ? 358 ASP D CG  1 
ATOM 2045 O OD1 . ASP D 1 269 ? 130.380 139.176 134.384 1.00 35.60 ? 358 ASP D OD1 1 
ATOM 2046 O OD2 . ASP D 1 269 ? 128.341 139.062 135.177 1.00 35.60 ? 358 ASP D OD2 1 
ATOM 2047 N N   . ASN D 1 270 ? 131.168 143.999 135.841 1.00 32.99 ? 359 ASN D N   1 
ATOM 2048 C CA  . ASN D 1 270 ? 131.160 145.404 136.276 1.00 32.99 ? 359 ASN D CA  1 
ATOM 2049 C C   . ASN D 1 270 ? 129.995 146.196 135.663 1.00 32.99 ? 359 ASN D C   1 
ATOM 2050 O O   . ASN D 1 270 ? 129.806 146.174 134.451 1.00 32.99 ? 359 ASN D O   1 
ATOM 2051 C CB  . ASN D 1 270 ? 132.497 146.078 135.941 1.00 32.99 ? 359 ASN D CB  1 
ATOM 2052 C CG  . ASN D 1 270 ? 133.698 145.351 136.506 1.00 32.99 ? 359 ASN D CG  1 
ATOM 2053 O OD1 . ASN D 1 270 ? 133.887 145.261 137.705 1.00 32.99 ? 359 ASN D OD1 1 
ATOM 2054 N ND2 . ASN D 1 270 ? 134.543 144.807 135.672 1.00 32.99 ? 359 ASN D ND2 1 
ATOM 2055 N N   . ILE D 1 271 ? 129.239 146.949 136.461 1.00 31.23 ? 360 ILE D N   1 
ATOM 2056 C CA  . ILE D 1 271 ? 128.065 147.709 135.993 1.00 31.23 ? 360 ILE D CA  1 
ATOM 2057 C C   . ILE D 1 271 ? 128.160 149.170 136.428 1.00 31.23 ? 360 ILE D C   1 
ATOM 2058 O O   . ILE D 1 271 ? 128.387 149.455 137.598 1.00 31.23 ? 360 ILE D O   1 
ATOM 2059 C CB  . ILE D 1 271 ? 126.749 147.060 136.488 1.00 31.23 ? 360 ILE D CB  1 
ATOM 2060 C CG1 . ILE D 1 271 ? 126.630 145.598 136.007 1.00 31.23 ? 360 ILE D CG1 1 
ATOM 2061 C CG2 . ILE D 1 271 ? 125.531 147.871 136.021 1.00 31.23 ? 360 ILE D CG2 1 
ATOM 2062 C CD1 . ILE D 1 271 ? 125.439 144.834 136.588 1.00 31.23 ? 360 ILE D CD1 1 
ATOM 2063 N N   . THR D 1 272 ? 127.927 150.104 135.514 1.00 32.74 ? 361 THR D N   1 
ATOM 2064 C CA  . THR D 1 272 ? 127.669 151.514 135.837 1.00 32.74 ? 361 THR D CA  1 
ATOM 2065 C C   . THR D 1 272 ? 126.269 151.869 135.361 1.00 32.74 ? 361 THR D C   1 
ATOM 2066 O O   . THR D 1 272 ? 126.001 151.794 134.167 1.00 32.74 ? 361 THR D O   1 
ATOM 2067 C CB  . THR D 1 272 ? 128.712 152.424 135.180 1.00 32.74 ? 361 THR D CB  1 
ATOM 2068 O OG1 . THR D 1 272 ? 130.001 152.030 135.580 1.00 32.74 ? 361 THR D OG1 1 
ATOM 2069 C CG2 . THR D 1 272 ? 128.553 153.883 135.588 1.00 32.74 ? 361 THR D CG2 1 
ATOM 2070 N N   . HIS D 1 273 ? 125.376 152.256 136.264 1.00 34.42 ? 362 HIS D N   1 
ATOM 2071 C CA  . HIS D 1 273 ? 123.972 152.547 135.964 1.00 34.42 ? 362 HIS D CA  1 
ATOM 2072 C C   . HIS D 1 273 ? 123.579 153.930 136.487 1.00 34.42 ? 362 HIS D C   1 
ATOM 2073 O O   . HIS D 1 273 ? 123.619 154.186 137.687 1.00 34.42 ? 362 HIS D O   1 
ATOM 2074 C CB  . HIS D 1 273 ? 123.111 151.405 136.520 1.00 34.42 ? 362 HIS D CB  1 
ATOM 2075 C CG  . HIS D 1 273 ? 121.651 151.490 136.161 1.00 34.42 ? 362 HIS D CG  1 
ATOM 2076 N ND1 . HIS D 1 273 ? 121.131 152.038 134.992 1.00 34.42 ? 362 HIS D ND1 1 
ATOM 2077 C CD2 . HIS D 1 273 ? 120.631 150.934 136.868 1.00 34.42 ? 362 HIS D CD2 1 
ATOM 2078 C CE1 . HIS D 1 273 ? 119.809 151.827 135.034 1.00 34.42 ? 362 HIS D CE1 1 
ATOM 2079 N NE2 . HIS D 1 273 ? 119.483 151.162 136.150 1.00 34.42 ? 362 HIS D NE2 1 
ATOM 2080 N N   . VAL D 1 274 ? 123.227 154.850 135.594 1.00 35.84 ? 363 VAL D N   1 
ATOM 2081 C CA  . VAL D 1 274 ? 122.986 156.262 135.927 1.00 35.84 ? 363 VAL D CA  1 
ATOM 2082 C C   . VAL D 1 274 ? 121.718 156.758 135.217 1.00 35.84 ? 363 VAL D C   1 
ATOM 2083 O O   . VAL D 1 274 ? 121.807 157.505 134.249 1.00 35.84 ? 363 VAL D O   1 
ATOM 2084 C CB  . VAL D 1 274 ? 124.231 157.134 135.625 1.00 35.84 ? 363 VAL D CB  1 
ATOM 2085 C CG1 . VAL D 1 274 ? 124.078 158.559 136.167 1.00 35.84 ? 363 VAL D CG1 1 
ATOM 2086 C CG2 . VAL D 1 274 ? 125.534 156.583 136.223 1.00 35.84 ? 363 VAL D CG2 1 
ATOM 2087 N N   . PRO D 1 275 ? 120.513 156.311 135.615 1.00 37.93 ? 364 PRO D N   1 
ATOM 2088 C CA  . PRO D 1 275 ? 119.280 156.781 135.001 1.00 37.93 ? 364 PRO D CA  1 
ATOM 2089 C C   . PRO D 1 275 ? 118.928 158.201 135.460 1.00 37.93 ? 364 PRO D C   1 
ATOM 2090 O O   . PRO D 1 275 ? 119.034 158.529 136.639 1.00 37.93 ? 364 PRO D O   1 
ATOM 2091 C CB  . PRO D 1 275 ? 118.222 155.752 135.403 1.00 37.93 ? 364 PRO D CB  1 
ATOM 2092 C CG  . PRO D 1 275 ? 118.707 155.268 136.760 1.00 37.93 ? 364 PRO D CG  1 
ATOM 2093 C CD  . PRO D 1 275 ? 120.229 155.322 136.639 1.00 37.93 ? 364 PRO D CD  1 
ATOM 2094 N N   . GLY D 1 276 ? 118.415 159.033 134.554 1.00 41.42 ? 365 GLY D N   1 
ATOM 2095 C CA  . GLY D 1 276 ? 118.000 160.400 134.879 1.00 41.42 ? 365 GLY D CA  1 
ATOM 2096 C C   . GLY D 1 276 ? 116.785 160.480 135.818 1.00 41.42 ? 365 GLY D C   1 
ATOM 2097 O O   . GLY D 1 276 ? 116.654 161.434 136.578 1.00 41.42 ? 365 GLY D O   1 
ATOM 2098 N N   . GLY D 1 277 ? 115.929 159.460 135.814 1.00 43.68 ? 366 GLY D N   1 
ATOM 2099 C CA  . GLY D 1 277 ? 114.827 159.267 136.751 1.00 43.68 ? 366 GLY D CA  1 
ATOM 2100 C C   . GLY D 1 277 ? 115.030 158.018 137.590 1.00 43.68 ? 366 GLY D C   1 
ATOM 2101 O O   . GLY D 1 277 ? 115.383 158.097 138.763 1.00 43.68 ? 366 GLY D O   1 
ATOM 2102 N N   . GLY D 1 278 ? 114.820 156.845 136.997 1.00 47.09 ? 367 GLY D N   1 
ATOM 2103 C CA  . GLY D 1 278 ? 115.048 155.561 137.670 1.00 47.09 ? 367 GLY D CA  1 
ATOM 2104 C C   . GLY D 1 278 ? 113.986 155.188 138.705 1.00 47.09 ? 367 GLY D C   1 
ATOM 2105 O O   . GLY D 1 278 ? 114.233 154.343 139.558 1.00 47.09 ? 367 GLY D O   1 
ATOM 2106 N N   . ASN D 1 279 ? 112.829 155.843 138.676 1.00 49.21 ? 368 ASN D N   1 
ATOM 2107 C CA  . ASN D 1 279 ? 111.689 155.560 139.545 1.00 49.21 ? 368 ASN D CA  1 
ATOM 2108 C C   . ASN D 1 279 ? 110.952 154.283 139.129 1.00 49.21 ? 368 ASN D C   1 
ATOM 2109 O O   . ASN D 1 279 ? 110.880 153.968 137.943 1.00 49.21 ? 368 ASN D O   1 
ATOM 2110 C CB  . ASN D 1 279 ? 110.763 156.782 139.545 1.00 49.21 ? 368 ASN D CB  1 
ATOM 2111 C CG  . ASN D 1 279 ? 111.463 158.013 140.063 1.00 49.21 ? 368 ASN D CG  1 
ATOM 2112 O OD1 . ASN D 1 279 ? 112.014 158.025 141.146 1.00 49.21 ? 368 ASN D OD1 1 
ATOM 2113 N ND2 . ASN D 1 279 ? 111.550 159.062 139.301 1.00 49.21 ? 368 ASN D ND2 1 
ATOM 2114 N N   . LYS D 1 280 ? 110.381 153.557 140.091 1.00 51.15 ? 369 LYS D N   1 
ATOM 2115 C CA  . LYS D 1 280 ? 109.713 152.264 139.885 1.00 51.15 ? 369 LYS D CA  1 
ATOM 2116 C C   . LYS D 1 280 ? 108.347 152.248 140.561 1.00 51.15 ? 369 LYS D C   1 
ATOM 2117 O O   . LYS D 1 280 ? 108.221 152.655 141.713 1.00 51.15 ? 369 LYS D O   1 
ATOM 2118 C CB  . LYS D 1 280 ? 110.595 151.122 140.428 1.00 51.15 ? 369 LYS D CB  1 
ATOM 2119 C CG  . LYS D 1 280 ? 111.976 151.046 139.758 1.00 51.15 ? 369 LYS D CG  1 
ATOM 2120 C CD  . LYS D 1 280 ? 112.879 149.924 140.286 1.00 51.15 ? 369 LYS D CD  1 
ATOM 2121 C CE  . LYS D 1 280 ? 112.344 148.525 139.969 1.00 51.15 ? 369 LYS D CE  1 
ATOM 2122 N NZ  . LYS D 1 280 ? 113.352 147.482 140.274 1.00 51.15 ? 369 LYS D NZ  1 
ATOM 2123 N N   . LYS D 1 281 ? 107.339 151.704 139.885 1.00 53.80 ? 370 LYS D N   1 
ATOM 2124 C CA  . LYS D 1 281 ? 106.018 151.416 140.460 1.00 53.80 ? 370 LYS D CA  1 
ATOM 2125 C C   . LYS D 1 281 ? 105.575 150.016 140.058 1.00 53.80 ? 370 LYS D C   1 
ATOM 2126 O O   . LYS D 1 281 ? 105.606 149.687 138.879 1.00 53.80 ? 370 LYS D O   1 
ATOM 2127 C CB  . LYS D 1 281 ? 105.059 152.531 140.037 1.00 53.80 ? 370 LYS D CB  1 
ATOM 2128 C CG  . LYS D 1 281 ? 103.605 152.348 140.492 1.00 53.80 ? 370 LYS D CG  1 
ATOM 2129 C CD  . LYS D 1 281 ? 102.835 153.633 140.156 1.00 53.80 ? 370 LYS D CD  1 
ATOM 2130 C CE  . LYS D 1 281 ? 101.318 153.463 140.071 1.00 53.80 ? 370 LYS D CE  1 
ATOM 2131 N NZ  . LYS D 1 281 ? 100.640 153.271 141.362 1.00 53.80 ? 370 LYS D NZ  1 
ATOM 2132 N N   . ILE D 1 282 ? 105.172 149.189 141.015 1.00 55.47 ? 371 ILE D N   1 
ATOM 2133 C CA  . ILE D 1 282 ? 104.757 147.801 140.769 1.00 55.47 ? 371 ILE D CA  1 
ATOM 2134 C C   . ILE D 1 282 ? 103.393 147.579 141.404 1.00 55.47 ? 371 ILE D C   1 
ATOM 2135 O O   . ILE D 1 282 ? 103.190 147.874 142.576 1.00 55.47 ? 371 ILE D O   1 
ATOM 2136 C CB  . ILE D 1 282 ? 105.797 146.791 141.306 1.00 55.47 ? 371 ILE D CB  1 
ATOM 2137 C CG1 . ILE D 1 282 ? 107.158 146.963 140.597 1.00 55.47 ? 371 ILE D CG1 1 
ATOM 2138 C CG2 . ILE D 1 282 ? 105.301 145.345 141.132 1.00 55.47 ? 371 ILE D CG2 1 
ATOM 2139 C CD1 . ILE D 1 282 ? 108.311 146.185 141.230 1.00 55.47 ? 371 ILE D CD1 1 
ATOM 2140 N N   . GLU D 1 283 ? 102.475 147.015 140.635 1.00 58.60 ? 372 GLU D N   1 
ATOM 2141 C CA  . GLU D 1 283 ? 101.084 146.770 141.005 1.00 58.60 ? 372 GLU D CA  1 
ATOM 2142 C C   . GLU D 1 283 ? 100.712 145.317 140.698 1.00 58.60 ? 372 GLU D C   1 
ATOM 2143 O O   . GLU D 1 283 ? 101.234 144.705 139.766 1.00 58.60 ? 372 GLU D O   1 
ATOM 2144 C CB  . GLU D 1 283 ? 100.173 147.713 140.209 1.00 58.60 ? 372 GLU D CB  1 
ATOM 2145 C CG  . GLU D 1 283 ? 100.492 149.216 140.327 1.00 58.60 ? 372 GLU D CG  1 
ATOM 2146 C CD  . GLU D 1 283 ? 100.133 149.837 141.682 1.00 58.60 ? 372 GLU D CD  1 
ATOM 2147 O OE1 . GLU D 1 283 ? 99.060  149.491 142.226 1.00 58.60 ? 372 GLU D OE1 1 
ATOM 2148 O OE2 . GLU D 1 283 ? 100.869 150.743 142.140 1.00 58.60 ? 372 GLU D OE2 1 
ATOM 2149 N N   . THR D 1 284 ? 99.807  144.726 141.470 1.00 61.89 ? 373 THR D N   1 
ATOM 2150 C CA  . THR D 1 284 ? 99.361  143.336 141.293 1.00 61.89 ? 373 THR D CA  1 
ATOM 2151 C C   . THR D 1 284 ? 97.963  143.167 141.871 1.00 61.89 ? 373 THR D C   1 
ATOM 2152 O O   . THR D 1 284 ? 97.753  143.440 143.049 1.00 61.89 ? 373 THR D O   1 
ATOM 2153 C CB  . THR D 1 284 ? 100.360 142.375 141.954 1.00 61.89 ? 373 THR D CB  1 
ATOM 2154 O OG1 . THR D 1 284 ? 101.507 142.283 141.145 1.00 61.89 ? 373 THR D OG1 1 
ATOM 2155 C CG2 . THR D 1 284 ? 99.853  140.948 142.108 1.00 61.89 ? 373 THR D CG2 1 
ATOM 2156 N N   . HIS D 1 285 ? 97.013  142.729 141.046 1.00 64.71 ? 374 HIS D N   1 
ATOM 2157 C CA  . HIS D 1 285 ? 95.609  142.486 141.387 1.00 64.71 ? 374 HIS D CA  1 
ATOM 2158 C C   . HIS D 1 285 ? 95.250  141.023 141.147 1.00 64.71 ? 374 HIS D C   1 
ATOM 2159 O O   . HIS D 1 285 ? 95.397  140.534 140.027 1.00 64.71 ? 374 HIS D O   1 
ATOM 2160 C CB  . HIS D 1 285 ? 94.725  143.384 140.512 1.00 64.71 ? 374 HIS D CB  1 
ATOM 2161 C CG  . HIS D 1 285 ? 94.883  144.865 140.741 1.00 64.71 ? 374 HIS D CG  1 
ATOM 2162 N ND1 . HIS D 1 285 ? 94.423  145.566 141.853 1.00 64.71 ? 374 HIS D ND1 1 
ATOM 2163 C CD2 . HIS D 1 285 ? 95.522  145.736 139.915 1.00 64.71 ? 374 HIS D CD2 1 
ATOM 2164 C CE1 . HIS D 1 285 ? 94.746  146.849 141.646 1.00 64.71 ? 374 HIS D CE1 1 
ATOM 2165 N NE2 . HIS D 1 285 ? 95.408  146.979 140.490 1.00 64.71 ? 374 HIS D NE2 1 
ATOM 2166 N N   . LYS D 1 286 ? 94.721  140.326 142.151 1.00 69.21 ? 375 LYS D N   1 
ATOM 2167 C CA  . LYS D 1 286 ? 94.332  138.913 142.039 1.00 69.21 ? 375 LYS D CA  1 
ATOM 2168 C C   . LYS D 1 286 ? 92.986  138.631 142.704 1.00 69.21 ? 375 LYS D C   1 
ATOM 2169 O O   . LYS D 1 286 ? 92.760  139.031 143.843 1.00 69.21 ? 375 LYS D O   1 
ATOM 2170 C CB  . LYS D 1 286 ? 95.471  138.053 142.611 1.00 69.21 ? 375 LYS D CB  1 
ATOM 2171 C CG  . LYS D 1 286 ? 95.222  136.553 142.407 1.00 69.21 ? 375 LYS D CG  1 
ATOM 2172 C CD  . LYS D 1 286 ? 96.465  135.691 142.666 1.00 69.21 ? 375 LYS D CD  1 
ATOM 2173 C CE  . LYS D 1 286 ? 97.509  135.844 141.551 1.00 69.21 ? 375 LYS D CE  1 
ATOM 2174 N NZ  . LYS D 1 286 ? 98.724  135.033 141.821 1.00 69.21 ? 375 LYS D NZ  1 
ATOM 2175 N N   . LEU D 1 287 ? 92.126  137.887 142.011 1.00 73.49 ? 376 LEU D N   1 
ATOM 2176 C CA  . LEU D 1 287 ? 90.858  137.362 142.526 1.00 73.49 ? 376 LEU D CA  1 
ATOM 2177 C C   . LEU D 1 287 ? 90.770  135.859 142.229 1.00 73.49 ? 376 LEU D C   1 
ATOM 2178 O O   . LEU D 1 287 ? 91.069  135.429 141.119 1.00 73.49 ? 376 LEU D O   1 
ATOM 2179 C CB  . LEU D 1 287 ? 89.690  138.191 141.954 1.00 73.49 ? 376 LEU D CB  1 
ATOM 2180 C CG  . LEU D 1 287 ? 88.283  137.646 142.257 1.00 73.49 ? 376 LEU D CG  1 
ATOM 2181 C CD1 . LEU D 1 287 ? 88.013  137.491 143.746 1.00 73.49 ? 376 LEU D CD1 1 
ATOM 2182 C CD2 . LEU D 1 287 ? 87.220  138.618 141.742 1.00 73.49 ? 376 LEU D CD2 1 
ATOM 2183 N N   . THR D 1 288 ? 90.415  135.028 143.209 1.00 77.93 ? 377 THR D N   1 
ATOM 2184 C CA  . THR D 1 288 ? 90.357  133.563 143.038 1.00 77.93 ? 377 THR D CA  1 
ATOM 2185 C C   . THR D 1 288 ? 89.150  132.916 143.716 1.00 77.93 ? 377 THR D C   1 
ATOM 2186 O O   . THR D 1 288 ? 88.815  133.250 144.849 1.00 77.93 ? 377 THR D O   1 
ATOM 2187 C CB  . THR D 1 288 ? 91.675  132.932 143.518 1.00 77.93 ? 377 THR D CB  1 
ATOM 2188 O OG1 . THR D 1 288 ? 92.718  133.392 142.694 1.00 77.93 ? 377 THR D OG1 1 
ATOM 2189 C CG2 . THR D 1 288 ? 91.729  131.408 143.458 1.00 77.93 ? 377 THR D CG2 1 
ATOM 2190 N N   . PHE D 1 289 ? 88.559  131.922 143.054 1.00 82.27 ? 378 PHE D N   1 
ATOM 2191 C CA  . PHE D 1 289 ? 87.493  131.060 143.575 1.00 82.27 ? 378 PHE D CA  1 
ATOM 2192 C C   . PHE D 1 289 ? 87.962  129.603 143.690 1.00 82.27 ? 378 PHE D C   1 
ATOM 2193 O O   . PHE D 1 289 ? 88.776  129.131 142.883 1.00 82.27 ? 378 PHE D O   1 
ATOM 2194 C CB  . PHE D 1 289 ? 86.250  131.179 142.683 1.00 82.27 ? 378 PHE D CB  1 
ATOM 2195 C CG  . PHE D 1 289 ? 85.631  132.559 142.699 1.00 82.27 ? 378 PHE D CG  1 
ATOM 2196 C CD1 . PHE D 1 289 ? 86.112  133.554 141.831 1.00 82.27 ? 378 PHE D CD1 1 
ATOM 2197 C CD2 . PHE D 1 289 ? 84.620  132.866 143.625 1.00 82.27 ? 378 PHE D CD2 1 
ATOM 2198 C CE1 . PHE D 1 289 ? 85.606  134.860 141.909 1.00 82.27 ? 378 PHE D CE1 1 
ATOM 2199 C CE2 . PHE D 1 289 ? 84.117  134.174 143.704 1.00 82.27 ? 378 PHE D CE2 1 
ATOM 2200 C CZ  . PHE D 1 289 ? 84.619  135.175 142.855 1.00 82.27 ? 378 PHE D CZ  1 
ATOM 2201 N N   . GLN E 1 218 ? 208.068 148.666 142.301 1.00 76.55 ? 307 GLN E N   1 
ATOM 2202 C CA  . GLN E 1 218 ? 207.680 147.456 141.584 1.00 76.55 ? 307 GLN E CA  1 
ATOM 2203 C C   . GLN E 1 218 ? 206.330 146.921 142.075 1.00 76.55 ? 307 GLN E C   1 
ATOM 2204 O O   . GLN E 1 218 ? 206.148 146.700 143.272 1.00 76.55 ? 307 GLN E O   1 
ATOM 2205 C CB  . GLN E 1 218 ? 208.784 146.397 141.754 1.00 76.55 ? 307 GLN E CB  1 
ATOM 2206 C CG  . GLN E 1 218 ? 208.483 145.069 141.038 1.00 76.55 ? 307 GLN E CG  1 
ATOM 2207 C CD  . GLN E 1 218 ? 209.601 144.032 141.177 1.00 76.55 ? 307 GLN E CD  1 
ATOM 2208 O OE1 . GLN E 1 218 ? 210.521 144.147 141.977 1.00 76.55 ? 307 GLN E OE1 1 
ATOM 2209 N NE2 . GLN E 1 218 ? 209.558 142.962 140.417 1.00 76.55 ? 307 GLN E NE2 1 
ATOM 2210 N N   . ILE E 1 219 ? 205.396 146.652 141.162 1.00 73.45 ? 308 ILE E N   1 
ATOM 2211 C CA  . ILE E 1 219 ? 204.096 146.047 141.474 1.00 73.45 ? 308 ILE E CA  1 
ATOM 2212 C C   . ILE E 1 219 ? 203.880 144.809 140.598 1.00 73.45 ? 308 ILE E C   1 
ATOM 2213 O O   . ILE E 1 219 ? 203.998 144.873 139.375 1.00 73.45 ? 308 ILE E O   1 
ATOM 2214 C CB  . ILE E 1 219 ? 202.955 147.083 141.317 1.00 73.45 ? 308 ILE E CB  1 
ATOM 2215 C CG1 . ILE E 1 219 ? 203.056 148.247 142.331 1.00 73.45 ? 308 ILE E CG1 1 
ATOM 2216 C CG2 . ILE E 1 219 ? 201.577 146.418 141.494 1.00 73.45 ? 308 ILE E CG2 1 
ATOM 2217 C CD1 . ILE E 1 219 ? 203.890 149.443 141.859 1.00 73.45 ? 308 ILE E CD1 1 
ATOM 2218 N N   . VAL E 1 220 ? 203.504 143.691 141.220 1.00 70.22 ? 309 VAL E N   1 
ATOM 2219 C CA  . VAL E 1 220 ? 203.248 142.397 140.570 1.00 70.22 ? 309 VAL E CA  1 
ATOM 2220 C C   . VAL E 1 220 ? 201.809 141.965 140.858 1.00 70.22 ? 309 VAL E C   1 
ATOM 2221 O O   . VAL E 1 220 ? 201.534 141.253 141.820 1.00 70.22 ? 309 VAL E O   1 
ATOM 2222 C CB  . VAL E 1 220 ? 204.280 141.332 140.990 1.00 70.22 ? 309 VAL E CB  1 
ATOM 2223 C CG1 . VAL E 1 220 ? 204.131 140.074 140.136 1.00 70.22 ? 309 VAL E CG1 1 
ATOM 2224 C CG2 . VAL E 1 220 ? 205.712 141.832 140.835 1.00 70.22 ? 309 VAL E CG2 1 
ATOM 2225 N N   . TYR E 1 221 ? 200.865 142.473 140.067 1.00 67.72 ? 310 TYR E N   1 
ATOM 2226 C CA  . TYR E 1 221 ? 199.439 142.180 140.208 1.00 67.72 ? 310 TYR E CA  1 
ATOM 2227 C C   . TYR E 1 221 ? 199.093 140.911 139.415 1.00 67.72 ? 310 TYR E C   1 
ATOM 2228 O O   . TYR E 1 221 ? 198.910 140.958 138.198 1.00 67.72 ? 310 TYR E O   1 
ATOM 2229 C CB  . TYR E 1 221 ? 198.660 143.422 139.758 1.00 67.72 ? 310 TYR E CB  1 
ATOM 2230 C CG  . TYR E 1 221 ? 197.176 143.412 140.058 1.00 67.72 ? 310 TYR E CG  1 
ATOM 2231 C CD1 . TYR E 1 221 ? 196.261 142.845 139.152 1.00 67.72 ? 310 TYR E CD1 1 
ATOM 2232 C CD2 . TYR E 1 221 ? 196.705 144.063 141.212 1.00 67.72 ? 310 TYR E CD2 1 
ATOM 2233 C CE1 . TYR E 1 221 ? 194.880 142.942 139.395 1.00 67.72 ? 310 TYR E CE1 1 
ATOM 2234 C CE2 . TYR E 1 221 ? 195.325 144.186 141.447 1.00 67.72 ? 310 TYR E CE2 1 
ATOM 2235 C CZ  . TYR E 1 221 ? 194.411 143.638 140.529 1.00 67.72 ? 310 TYR E CZ  1 
ATOM 2236 O OH  . TYR E 1 221 ? 193.082 143.813 140.730 1.00 67.72 ? 310 TYR E OH  1 
ATOM 2237 N N   . LYS E 1 222 ? 199.015 139.761 140.087 1.00 64.86 ? 311 LYS E N   1 
ATOM 2238 C CA  . LYS E 1 222 ? 198.944 138.432 139.457 1.00 64.86 ? 311 LYS E CA  1 
ATOM 2239 C C   . LYS E 1 222 ? 197.969 137.475 140.173 1.00 64.86 ? 311 LYS E C   1 
ATOM 2240 O O   . LYS E 1 222 ? 198.372 136.394 140.594 1.00 64.86 ? 311 LYS E O   1 
ATOM 2241 C CB  . LYS E 1 222 ? 200.386 137.891 139.352 1.00 64.86 ? 311 LYS E CB  1 
ATOM 2242 C CG  . LYS E 1 222 ? 200.540 136.734 138.357 1.00 64.86 ? 311 LYS E CG  1 
ATOM 2243 C CD  . LYS E 1 222 ? 201.998 136.297 138.204 1.00 64.86 ? 311 LYS E CD  1 
ATOM 2244 C CE  . LYS E 1 222 ? 202.101 135.192 137.148 1.00 64.86 ? 311 LYS E CE  1 
ATOM 2245 N NZ  . LYS E 1 222 ? 203.492 134.735 136.948 1.00 64.86 ? 311 LYS E NZ  1 
ATOM 2246 N N   . PRO E 1 223 ? 196.688 137.837 140.371 1.00 62.91 ? 312 PRO E N   1 
ATOM 2247 C CA  . PRO E 1 223 ? 195.692 136.922 140.929 1.00 62.91 ? 312 PRO E CA  1 
ATOM 2248 C C   . PRO E 1 223 ? 195.463 135.699 140.020 1.00 62.91 ? 312 PRO E C   1 
ATOM 2249 O O   . PRO E 1 223 ? 195.590 135.805 138.800 1.00 62.91 ? 312 PRO E O   1 
ATOM 2250 C CB  . PRO E 1 223 ? 194.424 137.763 141.085 1.00 62.91 ? 312 PRO E CB  1 
ATOM 2251 C CG  . PRO E 1 223 ? 194.548 138.793 139.974 1.00 62.91 ? 312 PRO E CG  1 
ATOM 2252 C CD  . PRO E 1 223 ? 196.048 139.070 139.943 1.00 62.91 ? 312 PRO E CD  1 
ATOM 2253 N N   . VAL E 1 224 ? 195.068 134.557 140.592 1.00 61.15 ? 313 VAL E N   1 
ATOM 2254 C CA  . VAL E 1 224 ? 194.755 133.319 139.847 1.00 61.15 ? 313 VAL E CA  1 
ATOM 2255 C C   . VAL E 1 224 ? 193.372 132.778 140.219 1.00 61.15 ? 313 VAL E C   1 
ATOM 2256 O O   . VAL E 1 224 ? 193.071 132.594 141.396 1.00 61.15 ? 313 VAL E O   1 
ATOM 2257 C CB  . VAL E 1 224 ? 195.829 132.238 140.083 1.00 61.15 ? 313 VAL E CB  1 
ATOM 2258 C CG1 . VAL E 1 224 ? 195.501 130.906 139.403 1.00 61.15 ? 313 VAL E CG1 1 
ATOM 2259 C CG2 . VAL E 1 224 ? 197.207 132.685 139.598 1.00 61.15 ? 313 VAL E CG2 1 
ATOM 2260 N N   . ASP E 1 225 ? 192.540 132.466 139.222 1.00 59.09 ? 314 ASP E N   1 
ATOM 2261 C CA  . ASP E 1 225 ? 191.203 131.888 139.414 1.00 59.09 ? 314 ASP E CA  1 
ATOM 2262 C C   . ASP E 1 225 ? 191.044 130.536 138.695 1.00 59.09 ? 314 ASP E C   1 
ATOM 2263 O O   . ASP E 1 225 ? 191.191 130.436 137.481 1.00 59.09 ? 314 ASP E O   1 
ATOM 2264 C CB  . ASP E 1 225 ? 190.155 132.912 138.953 1.00 59.09 ? 314 ASP E CB  1 
ATOM 2265 C CG  . ASP E 1 225 ? 188.698 132.437 139.062 1.00 59.09 ? 314 ASP E CG  1 
ATOM 2266 O OD1 . ASP E 1 225 ? 188.413 131.391 139.690 1.00 59.09 ? 314 ASP E OD1 1 
ATOM 2267 O OD2 . ASP E 1 225 ? 187.806 133.157 138.569 1.00 59.09 ? 314 ASP E OD2 1 
ATOM 2268 N N   . LEU E 1 226 ? 190.677 129.510 139.458 1.00 57.53 ? 315 LEU E N   1 
ATOM 2269 C CA  . LEU E 1 226 ? 190.453 128.118 139.061 1.00 57.53 ? 315 LEU E CA  1 
ATOM 2270 C C   . LEU E 1 226 ? 189.051 127.629 139.481 1.00 57.53 ? 315 LEU E C   1 
ATOM 2271 O O   . LEU E 1 226 ? 188.761 126.435 139.429 1.00 57.53 ? 315 LEU E O   1 
ATOM 2272 C CB  . LEU E 1 226 ? 191.574 127.267 139.694 1.00 57.53 ? 315 LEU E CB  1 
ATOM 2273 C CG  . LEU E 1 226 ? 192.981 127.538 139.130 1.00 57.53 ? 315 LEU E CG  1 
ATOM 2274 C CD1 . LEU E 1 226 ? 194.077 127.128 140.106 1.00 57.53 ? 315 LEU E CD1 1 
ATOM 2275 C CD2 . LEU E 1 226 ? 193.192 126.690 137.881 1.00 57.53 ? 315 LEU E CD2 1 
ATOM 2276 N N   . SER E 1 227 ? 188.185 128.537 139.932 1.00 56.45 ? 316 SER E N   1 
ATOM 2277 C CA  . SER E 1 227 ? 186.883 128.220 140.525 1.00 56.45 ? 316 SER E CA  1 
ATOM 2278 C C   . SER E 1 227 ? 185.853 127.611 139.561 1.00 56.45 ? 316 SER E C   1 
ATOM 2279 O O   . SER E 1 227 ? 185.948 127.747 138.341 1.00 56.45 ? 316 SER E O   1 
ATOM 2280 C CB  . SER E 1 227 ? 186.330 129.467 141.212 1.00 56.45 ? 316 SER E CB  1 
ATOM 2281 O OG  . SER E 1 227 ? 186.072 130.492 140.274 1.00 56.45 ? 316 SER E OG  1 
ATOM 2282 N N   . LYS E 1 228 ? 184.824 126.965 140.115 1.00 54.52 ? 317 LYS E N   1 
ATOM 2283 C CA  . LYS E 1 228 ? 183.721 126.346 139.359 1.00 54.52 ? 317 LYS E CA  1 
ATOM 2284 C C   . LYS E 1 228 ? 182.367 126.840 139.882 1.00 54.52 ? 317 LYS E C   1 
ATOM 2285 O O   . LYS E 1 228 ? 182.165 126.885 141.093 1.00 54.52 ? 317 LYS E O   1 
ATOM 2286 C CB  . LYS E 1 228 ? 183.775 124.809 139.510 1.00 54.52 ? 317 LYS E CB  1 
ATOM 2287 C CG  . LYS E 1 228 ? 185.082 124.106 139.115 1.00 54.52 ? 317 LYS E CG  1 
ATOM 2288 C CD  . LYS E 1 228 ? 185.385 124.183 137.614 1.00 54.52 ? 317 LYS E CD  1 
ATOM 2289 C CE  . LYS E 1 228 ? 186.584 123.305 137.221 1.00 54.52 ? 317 LYS E CE  1 
ATOM 2290 N NZ  . LYS E 1 228 ? 187.905 123.923 137.510 1.00 54.52 ? 317 LYS E NZ  1 
ATOM 2291 N N   . VAL E 1 229 ? 181.418 127.119 138.992 1.00 52.89 ? 318 VAL E N   1 
ATOM 2292 C CA  . VAL E 1 229 ? 179.991 127.282 139.317 1.00 52.89 ? 318 VAL E CA  1 
ATOM 2293 C C   . VAL E 1 229 ? 179.205 126.285 138.465 1.00 52.89 ? 318 VAL E C   1 
ATOM 2294 O O   . VAL E 1 229 ? 179.380 126.243 137.252 1.00 52.89 ? 318 VAL E O   1 
ATOM 2295 C CB  . VAL E 1 229 ? 179.512 128.731 139.117 1.00 52.89 ? 318 VAL E CB  1 
ATOM 2296 C CG1 . VAL E 1 229 ? 178.067 128.894 139.597 1.00 52.89 ? 318 VAL E CG1 1 
ATOM 2297 C CG2 . VAL E 1 229 ? 180.366 129.747 139.881 1.00 52.89 ? 318 VAL E CG2 1 
ATOM 2298 N N   . THR E 1 230 ? 178.413 125.402 139.063 1.00 52.42 ? 319 THR E N   1 
ATOM 2299 C CA  . THR E 1 230 ? 177.841 124.228 138.368 1.00 52.42 ? 319 THR E CA  1 
ATOM 2300 C C   . THR E 1 230 ? 176.439 123.884 138.850 1.00 52.42 ? 319 THR E C   1 
ATOM 2301 O O   . THR E 1 230 ? 176.086 124.142 139.996 1.00 52.42 ? 319 THR E O   1 
ATOM 2302 C CB  . THR E 1 230 ? 178.813 123.041 138.502 1.00 52.42 ? 319 THR E CB  1 
ATOM 2303 O OG1 . THR E 1 230 ? 179.978 123.329 137.765 1.00 52.42 ? 319 THR E OG1 1 
ATOM 2304 C CG2 . THR E 1 230 ? 178.311 121.687 138.004 1.00 52.42 ? 319 THR E CG2 1 
ATOM 2305 N N   . SER E 1 231 ? 175.605 123.280 138.002 1.00 49.96 ? 320 SER E N   1 
ATOM 2306 C CA  . SER E 1 231 ? 174.315 122.710 138.417 1.00 49.96 ? 320 SER E CA  1 
ATOM 2307 C C   . SER E 1 231 ? 173.891 121.516 137.574 1.00 49.96 ? 320 SER E C   1 
ATOM 2308 O O   . SER E 1 231 ? 174.183 121.457 136.380 1.00 49.96 ? 320 SER E O   1 
ATOM 2309 C CB  . SER E 1 231 ? 173.203 123.756 138.346 1.00 49.96 ? 320 SER E CB  1 
ATOM 2310 O OG  . SER E 1 231 ? 173.578 124.882 139.105 1.00 49.96 ? 320 SER E OG  1 
ATOM 2311 N N   . LYS E 1 232 ? 173.107 120.628 138.181 1.00 48.44 ? 321 LYS E N   1 
ATOM 2312 C CA  . LYS E 1 232 ? 172.356 119.563 137.512 1.00 48.44 ? 321 LYS E CA  1 
ATOM 2313 C C   . LYS E 1 232 ? 170.891 119.631 137.932 1.00 48.44 ? 321 LYS E C   1 
ATOM 2314 O O   . LYS E 1 232 ? 170.607 119.757 139.120 1.00 48.44 ? 321 LYS E O   1 
ATOM 2315 C CB  . LYS E 1 232 ? 172.951 118.196 137.880 1.00 48.44 ? 321 LYS E CB  1 
ATOM 2316 C CG  . LYS E 1 232 ? 174.365 118.004 137.327 1.00 48.44 ? 321 LYS E CG  1 
ATOM 2317 C CD  . LYS E 1 232 ? 174.849 116.568 137.557 1.00 48.44 ? 321 LYS E CD  1 
ATOM 2318 C CE  . LYS E 1 232 ? 176.244 116.383 136.951 1.00 48.44 ? 321 LYS E CE  1 
ATOM 2319 N NZ  . LYS E 1 232 ? 176.685 114.967 137.003 1.00 48.44 ? 321 LYS E NZ  1 
ATOM 2320 N N   . CYS E 1 233 ? 169.972 119.511 136.984 1.00 47.95 ? 322 CYS E N   1 
ATOM 2321 C CA  . CYS E 1 233 ? 168.537 119.446 137.244 1.00 47.95 ? 322 CYS E CA  1 
ATOM 2322 C C   . CYS E 1 233 ? 167.909 118.313 136.418 1.00 47.95 ? 322 CYS E C   1 
ATOM 2323 O O   . CYS E 1 233 ? 168.095 118.244 135.205 1.00 47.95 ? 322 CYS E O   1 
ATOM 2324 C CB  . CYS E 1 233 ? 167.944 120.832 136.957 1.00 47.95 ? 322 CYS E CB  1 
ATOM 2325 S SG  . CYS E 1 233 ? 166.180 120.876 137.360 1.00 47.95 ? 322 CYS E SG  1 
ATOM 2326 N N   . GLY E 1 234 ? 167.165 117.407 137.050 1.00 46.19 ? 323 GLY E N   1 
ATOM 2327 C CA  . GLY E 1 234 ? 166.689 116.187 136.387 1.00 46.19 ? 323 GLY E CA  1 
ATOM 2328 C C   . GLY E 1 234 ? 165.525 116.397 135.413 1.00 46.19 ? 323 GLY E C   1 
ATOM 2329 O O   . GLY E 1 234 ? 165.459 115.749 134.370 1.00 46.19 ? 323 GLY E O   1 
ATOM 2330 N N   . SER E 1 235 ? 164.622 117.322 135.725 1.00 44.59 ? 324 SER E N   1 
ATOM 2331 C CA  . SER E 1 235 ? 163.497 117.745 134.887 1.00 44.59 ? 324 SER E CA  1 
ATOM 2332 C C   . SER E 1 235 ? 162.945 119.058 135.422 1.00 44.59 ? 324 SER E C   1 
ATOM 2333 O O   . SER E 1 235 ? 162.857 119.221 136.637 1.00 44.59 ? 324 SER E O   1 
ATOM 2334 C CB  . SER E 1 235 ? 162.387 116.697 134.902 1.00 44.59 ? 324 SER E CB  1 
ATOM 2335 O OG  . SER E 1 235 ? 161.349 117.081 134.029 1.00 44.59 ? 324 SER E OG  1 
ATOM 2336 N N   . LEU E 1 236 ? 162.596 119.999 134.550 1.00 42.17 ? 325 LEU E N   1 
ATOM 2337 C CA  . LEU E 1 236 ? 162.176 121.346 134.925 1.00 42.17 ? 325 LEU E CA  1 
ATOM 2338 C C   . LEU E 1 236 ? 160.904 121.720 134.151 1.00 42.17 ? 325 LEU E C   1 
ATOM 2339 O O   . LEU E 1 236 ? 160.925 121.801 132.927 1.00 42.17 ? 325 LEU E O   1 
ATOM 2340 C CB  . LEU E 1 236 ? 163.392 122.270 134.712 1.00 42.17 ? 325 LEU E CB  1 
ATOM 2341 C CG  . LEU E 1 236 ? 163.186 123.766 134.977 1.00 42.17 ? 325 LEU E CG  1 
ATOM 2342 C CD1 . LEU E 1 236 ? 162.656 124.025 136.375 1.00 42.17 ? 325 LEU E CD1 1 
ATOM 2343 C CD2 . LEU E 1 236 ? 164.538 124.475 134.877 1.00 42.17 ? 325 LEU E CD2 1 
ATOM 2344 N N   . GLY E 1 237 ? 159.778 121.928 134.831 1.00 37.85 ? 326 GLY E N   1 
ATOM 2345 C CA  . GLY E 1 237 ? 158.511 122.154 134.126 1.00 37.85 ? 326 GLY E CA  1 
ATOM 2346 C C   . GLY E 1 237 ? 157.238 122.121 134.963 1.00 37.85 ? 326 GLY E C   1 
ATOM 2347 O O   . GLY E 1 237 ? 157.285 122.116 136.184 1.00 37.85 ? 326 GLY E O   1 
ATOM 2348 N N   . ASN E 1 238 ? 156.078 122.098 134.304 1.00 35.20 ? 327 ASN E N   1 
ATOM 2349 C CA  . ASN E 1 238 ? 154.750 122.228 134.923 1.00 35.20 ? 327 ASN E CA  1 
ATOM 2350 C C   . ASN E 1 238 ? 154.628 123.530 135.737 1.00 35.20 ? 327 ASN E C   1 
ATOM 2351 O O   . ASN E 1 238 ? 154.375 123.514 136.939 1.00 35.20 ? 327 ASN E O   1 
ATOM 2352 C CB  . ASN E 1 238 ? 154.385 120.935 135.683 1.00 35.20 ? 327 ASN E CB  1 
ATOM 2353 C CG  . ASN E 1 238 ? 152.928 120.899 136.114 1.00 35.20 ? 327 ASN E CG  1 
ATOM 2354 O OD1 . ASN E 1 238 ? 152.065 121.560 135.558 1.00 35.20 ? 327 ASN E OD1 1 
ATOM 2355 N ND2 . ASN E 1 238 ? 152.599 120.117 137.110 1.00 35.20 ? 327 ASN E ND2 1 
ATOM 2356 N N   . ILE E 1 239 ? 154.902 124.662 135.086 1.00 33.72 ? 328 ILE E N   1 
ATOM 2357 C CA  . ILE E 1 239 ? 154.924 126.005 135.689 1.00 33.72 ? 328 ILE E CA  1 
ATOM 2358 C C   . ILE E 1 239 ? 153.809 126.861 135.081 1.00 33.72 ? 328 ILE E C   1 
ATOM 2359 O O   . ILE E 1 239 ? 153.733 127.006 133.867 1.00 33.72 ? 328 ILE E O   1 
ATOM 2360 C CB  . ILE E 1 239 ? 156.321 126.647 135.539 1.00 33.72 ? 328 ILE E CB  1 
ATOM 2361 C CG1 . ILE E 1 239 ? 157.387 125.879 136.348 1.00 33.72 ? 328 ILE E CG1 1 
ATOM 2362 C CG2 . ILE E 1 239 ? 156.335 128.120 135.976 1.00 33.72 ? 328 ILE E CG2 1 
ATOM 2363 C CD1 . ILE E 1 239 ? 158.776 125.955 135.720 1.00 33.72 ? 328 ILE E CD1 1 
ATOM 2364 N N   . HIS E 1 240 ? 152.951 127.440 135.915 1.00 32.73 ? 329 HIS E N   1 
ATOM 2365 C CA  . HIS E 1 240 ? 151.799 128.249 135.510 1.00 32.73 ? 329 HIS E CA  1 
ATOM 2366 C C   . HIS E 1 240 ? 151.875 129.649 136.104 1.00 32.73 ? 329 HIS E C   1 
ATOM 2367 O O   . HIS E 1 240 ? 151.841 129.792 137.319 1.00 32.73 ? 329 HIS E O   1 
ATOM 2368 C CB  . HIS E 1 240 ? 150.514 127.548 135.964 1.00 32.73 ? 329 HIS E CB  1 
ATOM 2369 C CG  . HIS E 1 240 ? 150.346 126.158 135.411 1.00 32.73 ? 329 HIS E CG  1 
ATOM 2370 N ND1 . HIS E 1 240 ? 149.695 125.838 134.224 1.00 32.73 ? 329 HIS E ND1 1 
ATOM 2371 C CD2 . HIS E 1 240 ? 150.903 125.027 135.924 1.00 32.73 ? 329 HIS E CD2 1 
ATOM 2372 C CE1 . HIS E 1 240 ? 149.863 124.518 134.058 1.00 32.73 ? 329 HIS E CE1 1 
ATOM 2373 N NE2 . HIS E 1 240 ? 150.583 124.007 135.064 1.00 32.73 ? 329 HIS E NE2 1 
ATOM 2374 N N   . HIS E 1 241 ? 151.908 130.691 135.280 1.00 31.87 ? 330 HIS E N   1 
ATOM 2375 C CA  . HIS E 1 241 ? 151.841 132.089 135.712 1.00 31.87 ? 330 HIS E CA  1 
ATOM 2376 C C   . HIS E 1 241 ? 150.604 132.759 135.107 1.00 31.87 ? 330 HIS E C   1 
ATOM 2377 O O   . HIS E 1 241 ? 150.507 132.923 133.893 1.00 31.87 ? 330 HIS E O   1 
ATOM 2378 C CB  . HIS E 1 241 ? 153.157 132.782 135.335 1.00 31.87 ? 330 HIS E CB  1 
ATOM 2379 C CG  . HIS E 1 241 ? 153.318 134.213 135.792 1.00 31.87 ? 330 HIS E CG  1 
ATOM 2380 N ND1 . HIS E 1 241 ? 154.269 135.082 135.324 1.00 31.87 ? 330 HIS E ND1 1 
ATOM 2381 C CD2 . HIS E 1 241 ? 152.691 134.850 136.827 1.00 31.87 ? 330 HIS E CD2 1 
ATOM 2382 C CE1 . HIS E 1 241 ? 154.203 136.220 136.021 1.00 31.87 ? 330 HIS E CE1 1 
ATOM 2383 N NE2 . HIS E 1 241 ? 153.264 136.116 136.966 1.00 31.87 ? 330 HIS E NE2 1 
ATOM 2384 N N   . LYS E 1 242 ? 149.645 133.153 135.946 1.00 31.36 ? 331 LYS E N   1 
ATOM 2385 C CA  . LYS E 1 242 ? 148.289 133.571 135.551 1.00 31.36 ? 331 LYS E CA  1 
ATOM 2386 C C   . LYS E 1 242 ? 147.813 134.818 136.316 1.00 31.36 ? 331 LYS E C   1 
ATOM 2387 O O   . LYS E 1 242 ? 147.062 134.685 137.278 1.00 31.36 ? 331 LYS E O   1 
ATOM 2388 C CB  . LYS E 1 242 ? 147.343 132.369 135.755 1.00 31.36 ? 331 LYS E CB  1 
ATOM 2389 C CG  . LYS E 1 242 ? 147.538 131.249 134.727 1.00 31.36 ? 331 LYS E CG  1 
ATOM 2390 C CD  . LYS E 1 242 ? 146.895 129.913 135.114 1.00 31.36 ? 331 LYS E CD  1 
ATOM 2391 C CE  . LYS E 1 242 ? 145.365 129.958 135.162 1.00 31.36 ? 331 LYS E CE  1 
ATOM 2392 N NZ  . LYS E 1 242 ? 144.810 128.601 135.390 1.00 31.36 ? 331 LYS E NZ  1 
ATOM 2393 N N   . PRO E 1 243 ? 148.283 136.033 135.973 1.00 30.95 ? 332 PRO E N   1 
ATOM 2394 C CA  . PRO E 1 243 ? 147.838 137.276 136.617 1.00 30.95 ? 332 PRO E CA  1 
ATOM 2395 C C   . PRO E 1 243 ? 146.446 137.776 136.226 1.00 30.95 ? 332 PRO E C   1 
ATOM 2396 O O   . PRO E 1 243 ? 146.078 137.778 135.059 1.00 30.95 ? 332 PRO E O   1 
ATOM 2397 C CB  . PRO E 1 243 ? 148.910 138.322 136.297 1.00 30.95 ? 332 PRO E CB  1 
ATOM 2398 C CG  . PRO E 1 243 ? 150.114 137.500 135.865 1.00 30.95 ? 332 PRO E CG  1 
ATOM 2399 C CD  . PRO E 1 243 ? 149.477 136.302 135.189 1.00 30.95 ? 332 PRO E CD  1 
ATOM 2400 N N   . GLY E 1 244 ? 145.711 138.324 137.196 1.00 30.56 ? 333 GLY E N   1 
ATOM 2401 C CA  . GLY E 1 244 ? 144.339 138.824 137.055 1.00 30.56 ? 333 GLY E CA  1 
ATOM 2402 C C   . GLY E 1 244 ? 144.204 140.324 136.797 1.00 30.56 ? 333 GLY E C   1 
ATOM 2403 O O   . GLY E 1 244 ? 143.389 140.978 137.441 1.00 30.56 ? 333 GLY E O   1 
ATOM 2404 N N   . GLY E 1 245 ? 144.990 140.895 135.889 1.00 30.30 ? 334 GLY E N   1 
ATOM 2405 C CA  . GLY E 1 245 ? 144.876 142.303 135.493 1.00 30.30 ? 334 GLY E CA  1 
ATOM 2406 C C   . GLY E 1 245 ? 145.375 143.295 136.541 1.00 30.30 ? 334 GLY E C   1 
ATOM 2407 O O   . GLY E 1 245 ? 146.403 143.074 137.174 1.00 30.30 ? 334 GLY E O   1 
ATOM 2408 N N   . GLY E 1 246 ? 144.664 144.405 136.717 1.00 30.81 ? 335 GLY E N   1 
ATOM 2409 C CA  . GLY E 1 246 ? 145.010 145.478 137.649 1.00 30.81 ? 335 GLY E CA  1 
ATOM 2410 C C   . GLY E 1 246 ? 144.950 146.861 137.010 1.00 30.81 ? 335 GLY E C   1 
ATOM 2411 O O   . GLY E 1 246 ? 144.689 146.996 135.816 1.00 30.81 ? 335 GLY E O   1 
ATOM 2412 N N   . GLN E 1 247 ? 145.187 147.909 137.791 1.00 32.29 ? 336 GLN E N   1 
ATOM 2413 C CA  . GLN E 1 247 ? 145.128 149.287 137.302 1.00 32.29 ? 336 GLN E CA  1 
ATOM 2414 C C   . GLN E 1 247 ? 146.175 150.226 137.918 1.00 32.29 ? 336 GLN E C   1 
ATOM 2415 O O   . GLN E 1 247 ? 146.390 150.204 139.124 1.00 32.29 ? 336 GLN E O   1 
ATOM 2416 C CB  . GLN E 1 247 ? 143.696 149.770 137.504 1.00 32.29 ? 336 GLN E CB  1 
ATOM 2417 C CG  . GLN E 1 247 ? 143.392 151.107 136.837 1.00 32.29 ? 336 GLN E CG  1 
ATOM 2418 C CD  . GLN E 1 247 ? 141.890 151.235 136.719 1.00 32.29 ? 336 GLN E CD  1 
ATOM 2419 O OE1 . GLN E 1 247 ? 141.235 151.533 137.691 1.00 32.29 ? 336 GLN E OE1 1 
ATOM 2420 N NE2 . GLN E 1 247 ? 141.289 151.050 135.575 1.00 32.29 ? 336 GLN E NE2 1 
ATOM 2421 N N   . VAL E 1 248 ? 146.803 151.079 137.107 1.00 34.23 ? 337 VAL E N   1 
ATOM 2422 C CA  . VAL E 1 248 ? 147.876 152.001 137.527 1.00 34.23 ? 337 VAL E CA  1 
ATOM 2423 C C   . VAL E 1 248 ? 147.645 153.407 136.980 1.00 34.23 ? 337 VAL E C   1 
ATOM 2424 O O   . VAL E 1 248 ? 147.363 153.566 135.799 1.00 34.23 ? 337 VAL E O   1 
ATOM 2425 C CB  . VAL E 1 248 ? 149.260 151.478 137.090 1.00 34.23 ? 337 VAL E CB  1 
ATOM 2426 C CG1 . VAL E 1 248 ? 150.410 152.380 137.537 1.00 34.23 ? 337 VAL E CG1 1 
ATOM 2427 C CG2 . VAL E 1 248 ? 149.524 150.080 137.644 1.00 34.23 ? 337 VAL E CG2 1 
ATOM 2428 N N   . GLU E 1 249 ? 147.815 154.437 137.805 1.00 37.82 ? 338 GLU E N   1 
ATOM 2429 C CA  . GLU E 1 249 ? 147.716 155.842 137.403 1.00 37.82 ? 338 GLU E CA  1 
ATOM 2430 C C   . GLU E 1 249 ? 148.852 156.696 137.977 1.00 37.82 ? 338 GLU E C   1 
ATOM 2431 O O   . GLU E 1 249 ? 149.131 156.626 139.171 1.00 37.82 ? 338 GLU E O   1 
ATOM 2432 C CB  . GLU E 1 249 ? 146.346 156.373 137.826 1.00 37.82 ? 338 GLU E CB  1 
ATOM 2433 C CG  . GLU E 1 249 ? 146.147 157.848 137.468 1.00 37.82 ? 338 GLU E CG  1 
ATOM 2434 C CD  . GLU E 1 249 ? 144.727 158.353 137.756 1.00 37.82 ? 338 GLU E CD  1 
ATOM 2435 O OE1 . GLU E 1 249 ? 143.786 157.538 137.904 1.00 37.82 ? 338 GLU E OE1 1 
ATOM 2436 O OE2 . GLU E 1 249 ? 144.541 159.589 137.820 1.00 37.82 ? 338 GLU E OE2 1 
ATOM 2437 N N   . VAL E 1 250 ? 149.478 157.547 137.158 1.00 39.64 ? 339 VAL E N   1 
ATOM 2438 C CA  . VAL E 1 250 ? 150.550 158.460 137.593 1.00 39.64 ? 339 VAL E CA  1 
ATOM 2439 C C   . VAL E 1 250 ? 150.358 159.876 137.044 1.00 39.64 ? 339 VAL E C   1 
ATOM 2440 O O   . VAL E 1 250 ? 150.086 160.050 135.862 1.00 39.64 ? 339 VAL E O   1 
ATOM 2441 C CB  . VAL E 1 250 ? 151.947 157.913 137.235 1.00 39.64 ? 339 VAL E CB  1 
ATOM 2442 C CG1 . VAL E 1 250 ? 153.044 158.809 137.814 1.00 39.64 ? 339 VAL E CG1 1 
ATOM 2443 C CG2 . VAL E 1 250 ? 152.188 156.497 137.768 1.00 39.64 ? 339 VAL E CG2 1 
ATOM 2444 N N   . LYS E 1 251 ? 150.558 160.906 137.871 1.00 43.73 ? 340 LYS E N   1 
ATOM 2445 C CA  . LYS E 1 251 ? 150.459 162.324 137.483 1.00 43.73 ? 340 LYS E CA  1 
ATOM 2446 C C   . LYS E 1 251 ? 151.700 163.119 137.902 1.00 43.73 ? 340 LYS E C   1 
ATOM 2447 O O   . LYS E 1 251 ? 152.151 162.991 139.033 1.00 43.73 ? 340 LYS E O   1 
ATOM 2448 C CB  . LYS E 1 251 ? 149.177 162.904 138.095 1.00 43.73 ? 340 LYS E CB  1 
ATOM 2449 C CG  . LYS E 1 251 ? 148.928 164.342 137.618 1.00 43.73 ? 340 LYS E CG  1 
ATOM 2450 C CD  . LYS E 1 251 ? 147.631 164.949 138.164 1.00 43.73 ? 340 LYS E CD  1 
ATOM 2451 C CE  . LYS E 1 251 ? 146.368 164.245 137.658 1.00 43.73 ? 340 LYS E CE  1 
ATOM 2452 N NZ  . LYS E 1 251 ? 145.147 164.964 138.094 1.00 43.73 ? 340 LYS E NZ  1 
ATOM 2453 N N   . SER E 1 252 ? 152.200 163.978 137.016 1.00 48.33 ? 341 SER E N   1 
ATOM 2454 C CA  . SER E 1 252 ? 153.356 164.874 137.210 1.00 48.33 ? 341 SER E CA  1 
ATOM 2455 C C   . SER E 1 252 ? 153.110 166.224 136.528 1.00 48.33 ? 341 SER E C   1 
ATOM 2456 O O   . SER E 1 252 ? 152.334 166.292 135.580 1.00 48.33 ? 341 SER E O   1 
ATOM 2457 C CB  . SER E 1 252 ? 154.616 164.272 136.582 1.00 48.33 ? 341 SER E CB  1 
ATOM 2458 O OG  . SER E 1 252 ? 154.991 163.077 137.230 1.00 48.33 ? 341 SER E OG  1 
ATOM 2459 N N   . GLU E 1 253 ? 153.780 167.306 136.933 1.00 51.70 ? 342 GLU E N   1 
ATOM 2460 C CA  . GLU E 1 253 ? 153.893 168.492 136.070 1.00 51.70 ? 342 GLU E CA  1 
ATOM 2461 C C   . GLU E 1 253 ? 155.168 168.398 135.223 1.00 51.70 ? 342 GLU E C   1 
ATOM 2462 O O   . GLU E 1 253 ? 155.092 168.452 133.999 1.00 51.70 ? 342 GLU E O   1 
ATOM 2463 C CB  . GLU E 1 253 ? 153.900 169.807 136.866 1.00 51.70 ? 342 GLU E CB  1 
ATOM 2464 C CG  . GLU E 1 253 ? 152.761 169.956 137.889 1.00 51.70 ? 342 GLU E CG  1 
ATOM 2465 C CD  . GLU E 1 253 ? 151.347 170.011 137.294 1.00 51.70 ? 342 GLU E CD  1 
ATOM 2466 O OE1 . GLU E 1 253 ? 151.179 170.455 136.139 1.00 51.70 ? 342 GLU E OE1 1 
ATOM 2467 O OE2 . GLU E 1 253 ? 150.380 169.629 137.994 1.00 51.70 ? 342 GLU E OE2 1 
ATOM 2468 N N   . LYS E 1 254 ? 156.340 168.169 135.834 1.00 51.77 ? 343 LYS E N   1 
ATOM 2469 C CA  . LYS E 1 254 ? 157.632 168.231 135.125 1.00 51.77 ? 343 LYS E CA  1 
ATOM 2470 C C   . LYS E 1 254 ? 158.582 167.104 135.511 1.00 51.77 ? 343 LYS E C   1 
ATOM 2471 O O   . LYS E 1 254 ? 158.760 166.840 136.697 1.00 51.77 ? 343 LYS E O   1 
ATOM 2472 C CB  . LYS E 1 254 ? 158.319 169.575 135.428 1.00 51.77 ? 343 LYS E CB  1 
ATOM 2473 C CG  . LYS E 1 254 ? 157.507 170.792 134.973 1.00 51.77 ? 343 LYS E CG  1 
ATOM 2474 C CD  . LYS E 1 254 ? 158.340 172.072 135.071 1.00 51.77 ? 343 LYS E CD  1 
ATOM 2475 C CE  . LYS E 1 254 ? 157.495 173.269 134.621 1.00 51.77 ? 343 LYS E CE  1 
ATOM 2476 N NZ  . LYS E 1 254 ? 158.285 174.522 134.577 1.00 51.77 ? 343 LYS E NZ  1 
ATOM 2477 N N   . LEU E 1 255 ? 159.275 166.531 134.529 1.00 51.04 ? 344 LEU E N   1 
ATOM 2478 C CA  . LEU E 1 255 ? 160.378 165.587 134.720 1.00 51.04 ? 344 LEU E CA  1 
ATOM 2479 C C   . LEU E 1 255 ? 161.659 166.167 134.119 1.00 51.04 ? 344 LEU E C   1 
ATOM 2480 O O   . LEU E 1 255 ? 161.656 166.646 132.990 1.00 51.04 ? 344 LEU E O   1 
ATOM 2481 C CB  . LEU E 1 255 ? 160.063 164.211 134.097 1.00 51.04 ? 344 LEU E CB  1 
ATOM 2482 C CG  . LEU E 1 255 ? 158.729 163.559 134.500 1.00 51.04 ? 344 LEU E CG  1 
ATOM 2483 C CD1 . LEU E 1 255 ? 158.600 162.170 133.884 1.00 51.04 ? 344 LEU E CD1 1 
ATOM 2484 C CD2 . LEU E 1 255 ? 158.632 163.352 135.998 1.00 51.04 ? 344 LEU E CD2 1 
ATOM 2485 N N   . ASP E 1 256 ? 162.762 166.097 134.855 1.00 51.16 ? 345 ASP E N   1 
ATOM 2486 C CA  . ASP E 1 256 ? 164.043 166.701 134.477 1.00 51.16 ? 345 ASP E CA  1 
ATOM 2487 C C   . ASP E 1 256 ? 165.200 165.791 134.913 1.00 51.16 ? 345 ASP E C   1 
ATOM 2488 O O   . ASP E 1 256 ? 165.585 165.767 136.077 1.00 51.16 ? 345 ASP E O   1 
ATOM 2489 C CB  . ASP E 1 256 ? 164.076 168.104 135.098 1.00 51.16 ? 345 ASP E CB  1 
ATOM 2490 C CG  . ASP E 1 256 ? 165.283 168.957 134.701 1.00 51.16 ? 345 ASP E CG  1 
ATOM 2491 O OD1 . ASP E 1 256 ? 166.176 168.486 133.969 1.00 51.16 ? 345 ASP E OD1 1 
ATOM 2492 O OD2 . ASP E 1 256 ? 165.306 170.146 135.093 1.00 51.16 ? 345 ASP E OD2 1 
ATOM 2493 N N   . PHE E 1 257 ? 165.695 164.961 133.996 1.00 48.98 ? 346 PHE E N   1 
ATOM 2494 C CA  . PHE E 1 257 ? 166.662 163.896 134.283 1.00 48.98 ? 346 PHE E CA  1 
ATOM 2495 C C   . PHE E 1 257 ? 168.008 164.181 133.616 1.00 48.98 ? 346 PHE E C   1 
ATOM 2496 O O   . PHE E 1 257 ? 168.057 164.404 132.409 1.00 48.98 ? 346 PHE E O   1 
ATOM 2497 C CB  . PHE E 1 257 ? 166.115 162.529 133.840 1.00 48.98 ? 346 PHE E CB  1 
ATOM 2498 C CG  . PHE E 1 257 ? 164.794 162.042 134.423 1.00 48.98 ? 346 PHE E CG  1 
ATOM 2499 C CD1 . PHE E 1 257 ? 164.219 162.614 135.573 1.00 48.98 ? 346 PHE E CD1 1 
ATOM 2500 C CD2 . PHE E 1 257 ? 164.126 160.980 133.791 1.00 48.98 ? 346 PHE E CD2 1 
ATOM 2501 C CE1 . PHE E 1 257 ? 162.976 162.169 136.046 1.00 48.98 ? 346 PHE E CE1 1 
ATOM 2502 C CE2 . PHE E 1 257 ? 162.882 160.530 134.264 1.00 48.98 ? 346 PHE E CE2 1 
ATOM 2503 C CZ  . PHE E 1 257 ? 162.302 161.133 135.389 1.00 48.98 ? 346 PHE E CZ  1 
ATOM 2504 N N   . LYS E 1 258 ? 169.112 164.133 134.371 1.00 49.85 ? 347 LYS E N   1 
ATOM 2505 C CA  . LYS E 1 258 ? 170.469 164.399 133.871 1.00 49.85 ? 347 LYS E CA  1 
ATOM 2506 C C   . LYS E 1 258 ? 171.468 163.340 134.320 1.00 49.85 ? 347 LYS E C   1 
ATOM 2507 O O   . LYS E 1 258 ? 171.468 162.973 135.486 1.00 49.85 ? 347 LYS E O   1 
ATOM 2508 C CB  . LYS E 1 258 ? 170.968 165.777 134.342 1.00 49.85 ? 347 LYS E CB  1 
ATOM 2509 C CG  . LYS E 1 258 ? 170.045 166.922 133.921 1.00 49.85 ? 347 LYS E CG  1 
ATOM 2510 C CD  . LYS E 1 258 ? 170.638 168.284 134.287 1.00 49.85 ? 347 LYS E CD  1 
ATOM 2511 C CE  . LYS E 1 258 ? 169.623 169.376 133.932 1.00 49.85 ? 347 LYS E CE  1 
ATOM 2512 N NZ  . LYS E 1 258 ? 170.195 170.734 134.095 1.00 49.85 ? 347 LYS E NZ  1 
ATOM 2513 N N   . ASP E 1 259 ? 172.419 162.988 133.462 1.00 48.93 ? 348 ASP E N   1 
ATOM 2514 C CA  . ASP E 1 259 ? 173.655 162.284 133.825 1.00 48.93 ? 348 ASP E CA  1 
ATOM 2515 C C   . ASP E 1 259 ? 173.458 160.906 134.486 1.00 48.93 ? 348 ASP E C   1 
ATOM 2516 O O   . ASP E 1 259 ? 173.429 160.785 135.709 1.00 48.93 ? 348 ASP E O   1 
ATOM 2517 C CB  . ASP E 1 259 ? 174.523 163.235 134.666 1.00 48.93 ? 348 ASP E CB  1 
ATOM 2518 C CG  . ASP E 1 259 ? 175.861 162.620 135.060 1.00 48.93 ? 348 ASP E CG  1 
ATOM 2519 O OD1 . ASP E 1 259 ? 176.314 161.647 134.426 1.00 48.93 ? 348 ASP E OD1 1 
ATOM 2520 O OD2 . ASP E 1 259 ? 176.500 163.122 136.008 1.00 48.93 ? 348 ASP E OD2 1 
ATOM 2521 N N   . ARG E 1 260 ? 173.371 159.840 133.681 1.00 47.08 ? 349 ARG E N   1 
ATOM 2522 C CA  . ARG E 1 260 ? 173.254 158.445 134.160 1.00 47.08 ? 349 ARG E CA  1 
ATOM 2523 C C   . ARG E 1 260 ? 172.019 158.228 135.042 1.00 47.08 ? 349 ARG E C   1 
ATOM 2524 O O   . ARG E 1 260 ? 172.116 157.833 136.198 1.00 47.08 ? 349 ARG E O   1 
ATOM 2525 C CB  . ARG E 1 260 ? 174.571 157.963 134.800 1.00 47.08 ? 349 ARG E CB  1 
ATOM 2526 C CG  . ARG E 1 260 ? 175.716 157.863 133.777 1.00 47.08 ? 349 ARG E CG  1 
ATOM 2527 C CD  . ARG E 1 260 ? 177.079 157.846 134.469 1.00 47.08 ? 349 ARG E CD  1 
ATOM 2528 N NE  . ARG E 1 260 ? 177.368 159.179 135.023 1.00 47.08 ? 349 ARG E NE  1 
ATOM 2529 C CZ  . ARG E 1 260 ? 178.025 159.478 136.117 1.00 47.08 ? 349 ARG E CZ  1 
ATOM 2530 N NH1 . ARG E 1 260 ? 178.796 158.636 136.736 1.00 47.08 ? 349 ARG E NH1 1 
ATOM 2531 N NH2 . ARG E 1 260 ? 177.872 160.659 136.615 1.00 47.08 ? 349 ARG E NH2 1 
ATOM 2532 N N   . VAL E 1 261 ? 170.842 158.500 134.491 1.00 44.97 ? 350 VAL E N   1 
ATOM 2533 C CA  . VAL E 1 261 ? 169.546 158.219 135.123 1.00 44.97 ? 350 VAL E CA  1 
ATOM 2534 C C   . VAL E 1 261 ? 168.901 157.010 134.465 1.00 44.97 ? 350 VAL E C   1 
ATOM 2535 O O   . VAL E 1 261 ? 168.740 156.984 133.251 1.00 44.97 ? 350 VAL E O   1 
ATOM 2536 C CB  . VAL E 1 261 ? 168.611 159.439 135.066 1.00 44.97 ? 350 VAL E CB  1 
ATOM 2537 C CG1 . VAL E 1 261 ? 167.216 159.140 135.622 1.00 44.97 ? 350 VAL E CG1 1 
ATOM 2538 C CG2 . VAL E 1 261 ? 169.205 160.594 135.866 1.00 44.97 ? 350 VAL E CG2 1 
ATOM 2539 N N   . GLN E 1 262 ? 168.469 156.037 135.257 1.00 42.16 ? 351 GLN E N   1 
ATOM 2540 C CA  . GLN E 1 262 ? 167.630 154.928 134.820 1.00 42.16 ? 351 GLN E CA  1 
ATOM 2541 C C   . GLN E 1 262 ? 166.258 155.042 135.503 1.00 42.16 ? 351 GLN E C   1 
ATOM 2542 O O   . GLN E 1 262 ? 166.174 155.040 136.727 1.00 42.16 ? 351 GLN E O   1 
ATOM 2543 C CB  . GLN E 1 262 ? 168.376 153.626 135.120 1.00 42.16 ? 351 GLN E CB  1 
ATOM 2544 C CG  . GLN E 1 262 ? 167.617 152.384 134.640 1.00 42.16 ? 351 GLN E CG  1 
ATOM 2545 C CD  . GLN E 1 262 ? 168.339 151.073 134.946 1.00 42.16 ? 351 GLN E CD  1 
ATOM 2546 O OE1 . GLN E 1 262 ? 167.718 150.056 135.223 1.00 42.16 ? 351 GLN E OE1 1 
ATOM 2547 N NE2 . GLN E 1 262 ? 169.653 151.028 134.949 1.00 42.16 ? 351 GLN E NE2 1 
ATOM 2548 N N   . SER E 1 263 ? 165.180 155.176 134.735 1.00 40.18 ? 352 SER E N   1 
ATOM 2549 C CA  . SER E 1 263 ? 163.849 155.510 135.256 1.00 40.18 ? 352 SER E CA  1 
ATOM 2550 C C   . SER E 1 263 ? 162.744 154.638 134.664 1.00 40.18 ? 352 SER E C   1 
ATOM 2551 O O   . SER E 1 263 ? 162.751 154.353 133.470 1.00 40.18 ? 352 SER E O   1 
ATOM 2552 C CB  . SER E 1 263 ? 163.570 156.992 135.017 1.00 40.18 ? 352 SER E CB  1 
ATOM 2553 O OG  . SER E 1 263 ? 162.334 157.355 135.586 1.00 40.18 ? 352 SER E OG  1 
ATOM 2554 N N   . LYS E 1 264 ? 161.770 154.244 135.488 1.00 38.04 ? 353 LYS E N   1 
ATOM 2555 C CA  . LYS E 1 264 ? 160.549 153.535 135.089 1.00 38.04 ? 353 LYS E CA  1 
ATOM 2556 C C   . LYS E 1 264 ? 159.328 154.178 135.747 1.00 38.04 ? 353 LYS E C   1 
ATOM 2557 O O   . LYS E 1 264 ? 159.261 154.222 136.970 1.00 38.04 ? 353 LYS E O   1 
ATOM 2558 C CB  . LYS E 1 264 ? 160.728 152.056 135.463 1.00 38.04 ? 353 LYS E CB  1 
ATOM 2559 C CG  . LYS E 1 264 ? 159.648 151.156 134.857 1.00 38.04 ? 353 LYS E CG  1 
ATOM 2560 C CD  . LYS E 1 264 ? 159.813 149.698 135.313 1.00 38.04 ? 353 LYS E CD  1 
ATOM 2561 C CE  . LYS E 1 264 ? 158.803 148.835 134.551 1.00 38.04 ? 353 LYS E CE  1 
ATOM 2562 N NZ  . LYS E 1 264 ? 158.720 147.431 135.028 1.00 38.04 ? 353 LYS E NZ  1 
ATOM 2563 N N   . ILE E 1 265 ? 158.370 154.680 134.968 1.00 38.55 ? 354 ILE E N   1 
ATOM 2564 C CA  . ILE E 1 265 ? 157.173 155.382 135.466 1.00 38.55 ? 354 ILE E CA  1 
ATOM 2565 C C   . ILE E 1 265 ? 155.895 154.760 134.901 1.00 38.55 ? 354 ILE E C   1 
ATOM 2566 O O   . ILE E 1 265 ? 155.723 154.726 133.689 1.00 38.55 ? 354 ILE E O   1 
ATOM 2567 C CB  . ILE E 1 265 ? 157.253 156.900 135.166 1.00 38.55 ? 354 ILE E CB  1 
ATOM 2568 C CG1 . ILE E 1 265 ? 158.511 157.527 135.802 1.00 38.55 ? 354 ILE E CG1 1 
ATOM 2569 C CG2 . ILE E 1 265 ? 155.986 157.621 135.648 1.00 38.55 ? 354 ILE E CG2 1 
ATOM 2570 C CD1 . ILE E 1 265 ? 158.710 159.013 135.508 1.00 38.55 ? 354 ILE E CD1 1 
ATOM 2571 N N   . GLY E 1 266 ? 154.969 154.323 135.754 1.00 37.46 ? 355 GLY E N   1 
ATOM 2572 C CA  . GLY E 1 266 ? 153.672 153.786 135.339 1.00 37.46 ? 355 GLY E CA  1 
ATOM 2573 C C   . GLY E 1 266 ? 153.777 152.473 134.561 1.00 37.46 ? 355 GLY E C   1 
ATOM 2574 O O   . GLY E 1 266 ? 153.754 152.478 133.336 1.00 37.46 ? 355 GLY E O   1 
ATOM 2575 N N   . SER E 1 267 ? 153.861 151.329 135.236 1.00 36.13 ? 356 SER E N   1 
ATOM 2576 C CA  . SER E 1 267 ? 153.924 150.018 134.572 1.00 36.13 ? 356 SER E CA  1 
ATOM 2577 C C   . SER E 1 267 ? 152.999 148.964 135.154 1.00 36.13 ? 356 SER E C   1 
ATOM 2578 O O   . SER E 1 267 ? 152.695 148.974 136.343 1.00 36.13 ? 356 SER E O   1 
ATOM 2579 C CB  . SER E 1 267 ? 155.349 149.477 134.539 1.00 36.13 ? 356 SER E CB  1 
ATOM 2580 O OG  . SER E 1 267 ? 155.801 149.076 135.819 1.00 36.13 ? 356 SER E OG  1 
ATOM 2581 N N   . LEU E 1 268 ? 152.616 148.009 134.312 1.00 34.62 ? 357 LEU E N   1 
ATOM 2582 C CA  . LEU E 1 268 ? 151.933 146.781 134.701 1.00 34.62 ? 357 LEU E CA  1 
ATOM 2583 C C   . LEU E 1 268 ? 152.574 145.623 133.922 1.00 34.62 ? 357 LEU E C   1 
ATOM 2584 O O   . LEU E 1 268 ? 152.042 145.151 132.922 1.00 34.62 ? 357 LEU E O   1 
ATOM 2585 C CB  . LEU E 1 268 ? 150.419 147.000 134.493 1.00 34.62 ? 357 LEU E CB  1 
ATOM 2586 C CG  . LEU E 1 268 ? 149.480 146.008 135.199 1.00 34.62 ? 357 LEU E CG  1 
ATOM 2587 C CD1 . LEU E 1 268 ? 148.080 146.612 135.292 1.00 34.62 ? 357 LEU E CD1 1 
ATOM 2588 C CD2 . LEU E 1 268 ? 149.344 144.654 134.513 1.00 34.62 ? 357 LEU E CD2 1 
ATOM 2589 N N   . ASP E 1 269 ? 153.763 145.203 134.350 1.00 35.46 ? 358 ASP E N   1 
ATOM 2590 C CA  . ASP E 1 269 ? 154.621 144.280 133.600 1.00 35.46 ? 358 ASP E CA  1 
ATOM 2591 C C   . ASP E 1 269 ? 154.682 142.870 134.225 1.00 35.46 ? 358 ASP E C   1 
ATOM 2592 O O   . ASP E 1 269 ? 154.904 142.722 135.422 1.00 35.46 ? 358 ASP E O   1 
ATOM 2593 C CB  . ASP E 1 269 ? 156.027 144.877 133.439 1.00 35.46 ? 358 ASP E CB  1 
ATOM 2594 C CG  . ASP E 1 269 ? 156.142 146.195 132.643 1.00 35.46 ? 358 ASP E CG  1 
ATOM 2595 O OD1 . ASP E 1 269 ? 155.211 146.621 131.926 1.00 35.46 ? 358 ASP E OD1 1 
ATOM 2596 O OD2 . ASP E 1 269 ? 157.249 146.789 132.709 1.00 35.46 ? 358 ASP E OD2 1 
ATOM 2597 N N   . ASN E 1 270 ? 154.523 141.812 133.425 1.00 32.98 ? 359 ASN E N   1 
ATOM 2598 C CA  . ASN E 1 270 ? 154.554 140.409 133.863 1.00 32.98 ? 359 ASN E CA  1 
ATOM 2599 C C   . ASN E 1 270 ? 155.740 139.648 133.258 1.00 32.98 ? 359 ASN E C   1 
ATOM 2600 O O   . ASN E 1 270 ? 155.929 139.673 132.048 1.00 32.98 ? 359 ASN E O   1 
ATOM 2601 C CB  . ASN E 1 270 ? 153.238 139.712 133.494 1.00 32.98 ? 359 ASN E CB  1 
ATOM 2602 C CG  . ASN E 1 270 ? 152.012 140.411 134.038 1.00 32.98 ? 359 ASN E CG  1 
ATOM 2603 O OD1 . ASN E 1 270 ? 151.785 140.478 135.231 1.00 32.98 ? 359 ASN E OD1 1 
ATOM 2604 N ND2 . ASN E 1 270 ? 151.197 140.971 133.185 1.00 32.98 ? 359 ASN E ND2 1 
ATOM 2605 N N   . ILE E 1 271 ? 156.512 138.913 134.058 1.00 31.86 ? 360 ILE E N   1 
ATOM 2606 C CA  . ILE E 1 271 ? 157.691 138.157 133.591 1.00 31.86 ? 360 ILE E CA  1 
ATOM 2607 C C   . ILE E 1 271 ? 157.600 136.700 134.039 1.00 31.86 ? 360 ILE E C   1 
ATOM 2608 O O   . ILE E 1 271 ? 157.379 136.421 135.212 1.00 31.86 ? 360 ILE E O   1 
ATOM 2609 C CB  . ILE E 1 271 ? 159.009 138.810 134.078 1.00 31.86 ? 360 ILE E CB  1 
ATOM 2610 C CG1 . ILE E 1 271 ? 159.149 140.265 133.586 1.00 31.86 ? 360 ILE E CG1 1 
ATOM 2611 C CG2 . ILE E 1 271 ? 160.226 137.988 133.633 1.00 31.86 ? 360 ILE E CG2 1 
ATOM 2612 C CD1 . ILE E 1 271 ? 160.314 141.042 134.176 1.00 31.86 ? 360 ILE E CD1 1 
ATOM 2613 N N   . THR E 1 272 ? 157.829 135.757 133.131 1.00 32.83 ? 361 THR E N   1 
ATOM 2614 C CA  . THR E 1 272 ? 158.093 134.352 133.465 1.00 32.83 ? 361 THR E CA  1 
ATOM 2615 C C   . THR E 1 272 ? 159.489 134.002 132.980 1.00 32.83 ? 361 THR E C   1 
ATOM 2616 O O   . THR E 1 272 ? 159.746 134.074 131.784 1.00 32.83 ? 361 THR E O   1 
ATOM 2617 C CB  . THR E 1 272 ? 157.061 133.427 132.815 1.00 32.83 ? 361 THR E CB  1 
ATOM 2618 O OG1 . THR E 1 272 ? 155.771 133.820 133.203 1.00 32.83 ? 361 THR E OG1 1 
ATOM 2619 C CG2 . THR E 1 272 ? 157.223 131.980 133.247 1.00 32.83 ? 361 THR E CG2 1 
ATOM 2620 N N   . HIS E 1 273 ? 160.405 133.641 133.875 1.00 34.46 ? 362 HIS E N   1 
ATOM 2621 C CA  . HIS E 1 273 ? 161.807 133.355 133.556 1.00 34.46 ? 362 HIS E CA  1 
ATOM 2622 C C   . HIS E 1 273 ? 162.211 131.974 134.079 1.00 34.46 ? 362 HIS E C   1 
ATOM 2623 O O   . HIS E 1 273 ? 162.173 131.716 135.277 1.00 34.46 ? 362 HIS E O   1 
ATOM 2624 C CB  . HIS E 1 273 ? 162.679 134.500 134.098 1.00 34.46 ? 362 HIS E CB  1 
ATOM 2625 C CG  . HIS E 1 273 ? 164.129 134.424 133.702 1.00 34.46 ? 362 HIS E CG  1 
ATOM 2626 N ND1 . HIS E 1 273 ? 164.615 133.895 132.510 1.00 34.46 ? 362 HIS E ND1 1 
ATOM 2627 C CD2 . HIS E 1 273 ? 165.171 134.976 134.381 1.00 34.46 ? 362 HIS E CD2 1 
ATOM 2628 C CE1 . HIS E 1 273 ? 165.937 134.105 132.516 1.00 34.46 ? 362 HIS E CE1 1 
ATOM 2629 N NE2 . HIS E 1 273 ? 166.297 134.756 133.628 1.00 34.46 ? 362 HIS E NE2 1 
ATOM 2630 N N   . VAL E 1 274 ? 162.564 131.056 133.185 1.00 36.17 ? 363 VAL E N   1 
ATOM 2631 C CA  . VAL E 1 274 ? 162.811 129.642 133.513 1.00 36.17 ? 363 VAL E CA  1 
ATOM 2632 C C   . VAL E 1 274 ? 164.075 129.149 132.791 1.00 36.17 ? 363 VAL E C   1 
ATOM 2633 O O   . VAL E 1 274 ? 163.976 128.406 131.820 1.00 36.17 ? 363 VAL E O   1 
ATOM 2634 C CB  . VAL E 1 274 ? 161.564 128.767 133.229 1.00 36.17 ? 363 VAL E CB  1 
ATOM 2635 C CG1 . VAL E 1 274 ? 161.717 127.346 133.774 1.00 36.17 ? 363 VAL E CG1 1 
ATOM 2636 C CG2 . VAL E 1 274 ? 160.265 129.324 133.826 1.00 36.17 ? 363 VAL E CG2 1 
ATOM 2637 N N   . PRO E 1 275 ? 165.278 129.598 133.189 1.00 38.35 ? 364 PRO E N   1 
ATOM 2638 C CA  . PRO E 1 275 ? 166.519 129.137 132.582 1.00 38.35 ? 364 PRO E CA  1 
ATOM 2639 C C   . PRO E 1 275 ? 166.885 127.719 133.040 1.00 38.35 ? 364 PRO E C   1 
ATOM 2640 O O   . PRO E 1 275 ? 166.800 127.394 134.223 1.00 38.35 ? 364 PRO E O   1 
ATOM 2641 C CB  . PRO E 1 275 ? 167.568 130.173 133.001 1.00 38.35 ? 364 PRO E CB  1 
ATOM 2642 C CG  . PRO E 1 275 ? 167.068 130.650 134.355 1.00 38.35 ? 364 PRO E CG  1 
ATOM 2643 C CD  . PRO E 1 275 ? 165.549 130.587 134.217 1.00 38.35 ? 364 PRO E CD  1 
ATOM 2644 N N   . GLY E 1 276 ? 167.394 126.891 132.129 1.00 42.41 ? 365 GLY E N   1 
ATOM 2645 C CA  . GLY E 1 276 ? 167.822 125.528 132.452 1.00 42.41 ? 365 GLY E CA  1 
ATOM 2646 C C   . GLY E 1 276 ? 169.040 125.463 133.383 1.00 42.41 ? 365 GLY E C   1 
ATOM 2647 O O   . GLY E 1 276 ? 169.180 124.518 134.153 1.00 42.41 ? 365 GLY E O   1 
ATOM 2648 N N   . GLY E 1 277 ? 169.890 126.488 133.365 1.00 44.65 ? 366 GLY E N   1 
ATOM 2649 C CA  . GLY E 1 277 ? 170.999 126.697 134.290 1.00 44.65 ? 366 GLY E CA  1 
ATOM 2650 C C   . GLY E 1 277 ? 170.805 127.948 135.128 1.00 44.65 ? 366 GLY E C   1 
ATOM 2651 O O   . GLY E 1 277 ? 170.448 127.872 136.299 1.00 44.65 ? 366 GLY E O   1 
ATOM 2652 N N   . GLY E 1 278 ? 171.018 129.120 134.534 1.00 47.72 ? 367 GLY E N   1 
ATOM 2653 C CA  . GLY E 1 278 ? 170.783 130.407 135.199 1.00 47.72 ? 367 GLY E CA  1 
ATOM 2654 C C   . GLY E 1 278 ? 171.837 130.807 136.236 1.00 47.72 ? 367 GLY E C   1 
ATOM 2655 O O   . GLY E 1 278 ? 171.574 131.657 137.080 1.00 47.72 ? 367 GLY E O   1 
ATOM 2656 N N   . ASN E 1 279 ? 173.003 130.170 136.224 1.00 50.20 ? 368 ASN E N   1 
ATOM 2657 C CA  . ASN E 1 279 ? 174.126 130.487 137.105 1.00 50.20 ? 368 ASN E CA  1 
ATOM 2658 C C   . ASN E 1 279 ? 174.861 131.768 136.682 1.00 50.20 ? 368 ASN E C   1 
ATOM 2659 O O   . ASN E 1 279 ? 174.955 132.072 135.494 1.00 50.20 ? 368 ASN E O   1 
ATOM 2660 C CB  . ASN E 1 279 ? 175.068 129.279 137.156 1.00 50.20 ? 368 ASN E CB  1 
ATOM 2661 C CG  . ASN E 1 279 ? 174.385 128.042 137.687 1.00 50.20 ? 368 ASN E CG  1 
ATOM 2662 O OD1 . ASN E 1 279 ? 173.802 128.034 138.753 1.00 50.20 ? 368 ASN E OD1 1 
ATOM 2663 N ND2 . ASN E 1 279 ? 174.381 126.963 136.960 1.00 50.20 ? 368 ASN E ND2 1 
ATOM 2664 N N   . LYS E 1 280 ? 175.415 132.503 137.648 1.00 51.65 ? 369 LYS E N   1 
ATOM 2665 C CA  . LYS E 1 280 ? 176.075 133.803 137.450 1.00 51.65 ? 369 LYS E CA  1 
ATOM 2666 C C   . LYS E 1 280 ? 177.443 133.827 138.122 1.00 51.65 ? 369 LYS E C   1 
ATOM 2667 O O   . LYS E 1 280 ? 177.575 133.403 139.267 1.00 51.65 ? 369 LYS E O   1 
ATOM 2668 C CB  . LYS E 1 280 ? 175.191 134.931 138.013 1.00 51.65 ? 369 LYS E CB  1 
ATOM 2669 C CG  . LYS E 1 280 ? 173.809 135.023 137.346 1.00 51.65 ? 369 LYS E CG  1 
ATOM 2670 C CD  . LYS E 1 280 ? 172.922 136.137 137.920 1.00 51.65 ? 369 LYS E CD  1 
ATOM 2671 C CE  . LYS E 1 280 ? 173.482 137.539 137.654 1.00 51.65 ? 369 LYS E CE  1 
ATOM 2672 N NZ  . LYS E 1 280 ? 172.495 138.591 138.001 1.00 51.65 ? 369 LYS E NZ  1 
ATOM 2673 N N   . LYS E 1 281 ? 178.449 134.386 137.456 1.00 54.62 ? 370 LYS E N   1 
ATOM 2674 C CA  . LYS E 1 281 ? 179.758 134.692 138.047 1.00 54.62 ? 370 LYS E CA  1 
ATOM 2675 C C   . LYS E 1 281 ? 180.196 136.091 137.635 1.00 54.62 ? 370 LYS E C   1 
ATOM 2676 O O   . LYS E 1 281 ? 180.175 136.412 136.453 1.00 54.62 ? 370 LYS E O   1 
ATOM 2677 C CB  . LYS E 1 281 ? 180.731 133.576 137.654 1.00 54.62 ? 370 LYS E CB  1 
ATOM 2678 C CG  . LYS E 1 281 ? 182.184 133.770 138.118 1.00 54.62 ? 370 LYS E CG  1 
ATOM 2679 C CD  . LYS E 1 281 ? 182.957 132.475 137.816 1.00 54.62 ? 370 LYS E CD  1 
ATOM 2680 C CE  . LYS E 1 281 ? 184.476 132.644 137.729 1.00 54.62 ? 370 LYS E CE  1 
ATOM 2681 N NZ  . LYS E 1 281 ? 185.161 132.876 139.011 1.00 54.62 ? 370 LYS E NZ  1 
ATOM 2682 N N   . ILE E 1 282 ? 180.579 136.921 138.599 1.00 55.60 ? 371 ILE E N   1 
ATOM 2683 C CA  . ILE E 1 282 ? 180.976 138.317 138.377 1.00 55.60 ? 371 ILE E CA  1 
ATOM 2684 C C   . ILE E 1 282 ? 182.344 138.540 139.002 1.00 55.60 ? 371 ILE E C   1 
ATOM 2685 O O   . ILE E 1 282 ? 182.562 138.233 140.169 1.00 55.60 ? 371 ILE E O   1 
ATOM 2686 C CB  . ILE E 1 282 ? 179.933 139.301 138.949 1.00 55.60 ? 371 ILE E CB  1 
ATOM 2687 C CG1 . ILE E 1 282 ? 178.581 139.161 138.221 1.00 55.60 ? 371 ILE E CG1 1 
ATOM 2688 C CG2 . ILE E 1 282 ? 180.431 140.754 138.857 1.00 55.60 ? 371 ILE E CG2 1 
ATOM 2689 C CD1 . ILE E 1 282 ? 177.423 139.913 138.883 1.00 55.60 ? 371 ILE E CD1 1 
ATOM 2690 N N   . GLU E 1 283 ? 183.248 139.128 138.234 1.00 57.98 ? 372 GLU E N   1 
ATOM 2691 C CA  . GLU E 1 283 ? 184.637 139.385 138.604 1.00 57.98 ? 372 GLU E CA  1 
ATOM 2692 C C   . GLU E 1 283 ? 184.985 140.847 138.320 1.00 57.98 ? 372 GLU E C   1 
ATOM 2693 O O   . GLU E 1 283 ? 184.447 141.464 137.402 1.00 57.98 ? 372 GLU E O   1 
ATOM 2694 C CB  . GLU E 1 283 ? 185.558 138.466 137.792 1.00 57.98 ? 372 GLU E CB  1 
ATOM 2695 C CG  . GLU E 1 283 ? 185.248 136.960 137.886 1.00 57.98 ? 372 GLU E CG  1 
ATOM 2696 C CD  . GLU E 1 283 ? 185.602 136.329 139.238 1.00 57.98 ? 372 GLU E CD  1 
ATOM 2697 O OE1 . GLU E 1 283 ? 186.664 136.680 139.799 1.00 57.98 ? 372 GLU E OE1 1 
ATOM 2698 O OE2 . GLU E 1 283 ? 184.866 135.415 139.680 1.00 57.98 ? 372 GLU E OE2 1 
ATOM 2699 N N   . THR E 1 284 ? 185.894 141.440 139.087 1.00 61.09 ? 373 THR E N   1 
ATOM 2700 C CA  . THR E 1 284 ? 186.334 142.829 138.885 1.00 61.09 ? 373 THR E CA  1 
ATOM 2701 C C   . THR E 1 284 ? 187.739 143.015 139.435 1.00 61.09 ? 373 THR E C   1 
ATOM 2702 O O   . THR E 1 284 ? 187.965 142.764 140.613 1.00 61.09 ? 373 THR E O   1 
ATOM 2703 C CB  . THR E 1 284 ? 185.345 143.803 139.545 1.00 61.09 ? 373 THR E CB  1 
ATOM 2704 O OG1 . THR E 1 284 ? 184.196 143.892 138.739 1.00 61.09 ? 373 THR E OG1 1 
ATOM 2705 C CG2 . THR E 1 284 ? 185.861 145.230 139.694 1.00 61.09 ? 373 THR E CG2 1 
ATOM 2706 N N   . HIS E 1 285 ? 188.672 143.457 138.598 1.00 63.04 ? 374 HIS E N   1 
ATOM 2707 C CA  . HIS E 1 285 ? 190.068 143.726 138.940 1.00 63.04 ? 374 HIS E CA  1 
ATOM 2708 C C   . HIS E 1 285 ? 190.393 145.194 138.703 1.00 63.04 ? 374 HIS E C   1 
ATOM 2709 O O   . HIS E 1 285 ? 190.211 145.693 137.593 1.00 63.04 ? 374 HIS E O   1 
ATOM 2710 C CB  . HIS E 1 285 ? 190.973 142.859 138.064 1.00 63.04 ? 374 HIS E CB  1 
ATOM 2711 C CG  . HIS E 1 285 ? 190.820 141.377 138.274 1.00 63.04 ? 374 HIS E CG  1 
ATOM 2712 N ND1 . HIS E 1 285 ? 191.278 140.665 139.378 1.00 63.04 ? 374 HIS E ND1 1 
ATOM 2713 C CD2 . HIS E 1 285 ? 190.137 140.530 137.460 1.00 63.04 ? 374 HIS E CD2 1 
ATOM 2714 C CE1 . HIS E 1 285 ? 190.904 139.395 139.180 1.00 63.04 ? 374 HIS E CE1 1 
ATOM 2715 N NE2 . HIS E 1 285 ? 190.213 139.288 138.038 1.00 63.04 ? 374 HIS E NE2 1 
ATOM 2716 N N   . LYS E 1 286 ? 190.929 145.883 139.708 1.00 66.96 ? 375 LYS E N   1 
ATOM 2717 C CA  . LYS E 1 286 ? 191.308 147.299 139.616 1.00 66.96 ? 375 LYS E CA  1 
ATOM 2718 C C   . LYS E 1 286 ? 192.672 147.562 140.252 1.00 66.96 ? 375 LYS E C   1 
ATOM 2719 O O   . LYS E 1 286 ? 192.933 147.105 141.364 1.00 66.96 ? 375 LYS E O   1 
ATOM 2720 C CB  . LYS E 1 286 ? 190.190 148.137 140.258 1.00 66.96 ? 375 LYS E CB  1 
ATOM 2721 C CG  . LYS E 1 286 ? 190.407 149.648 140.084 1.00 66.96 ? 375 LYS E CG  1 
ATOM 2722 C CD  . LYS E 1 286 ? 189.158 150.472 140.434 1.00 66.96 ? 375 LYS E CD  1 
ATOM 2723 C CE  . LYS E 1 286 ? 188.050 150.338 139.380 1.00 66.96 ? 375 LYS E CE  1 
ATOM 2724 N NZ  . LYS E 1 286 ? 186.843 151.126 139.742 1.00 66.96 ? 375 LYS E NZ  1 
ATOM 2725 N N   . LEU E 1 287 ? 193.511 148.334 139.564 1.00 70.56 ? 376 LEU E N   1 
ATOM 2726 C CA  . LEU E 1 287 ? 194.777 148.879 140.066 1.00 70.56 ? 376 LEU E CA  1 
ATOM 2727 C C   . LEU E 1 287 ? 194.846 150.376 139.750 1.00 70.56 ? 376 LEU E C   1 
ATOM 2728 O O   . LEU E 1 287 ? 194.508 150.792 138.644 1.00 70.56 ? 376 LEU E O   1 
ATOM 2729 C CB  . LEU E 1 287 ? 195.958 148.062 139.507 1.00 70.56 ? 376 LEU E CB  1 
ATOM 2730 C CG  . LEU E 1 287 ? 197.362 148.632 139.802 1.00 70.56 ? 376 LEU E CG  1 
ATOM 2731 C CD1 . LEU E 1 287 ? 197.646 148.806 141.289 1.00 70.56 ? 376 LEU E CD1 1 
ATOM 2732 C CD2 . LEU E 1 287 ? 198.437 147.675 139.282 1.00 70.56 ? 376 LEU E CD2 1 
ATOM 2733 N N   . THR E 1 288 ? 195.205 151.225 140.712 1.00 73.81 ? 377 THR E N   1 
ATOM 2734 C CA  . THR E 1 288 ? 195.211 152.690 140.532 1.00 73.81 ? 377 THR E CA  1 
ATOM 2735 C C   . THR E 1 288 ? 196.389 153.394 141.206 1.00 73.81 ? 377 THR E C   1 
ATOM 2736 O O   . THR E 1 288 ? 196.738 153.070 142.338 1.00 73.81 ? 377 THR E O   1 
ATOM 2737 C CB  . THR E 1 288 ? 193.862 153.252 141.006 1.00 73.81 ? 377 THR E CB  1 
ATOM 2738 O OG1 . THR E 1 288 ? 192.845 152.758 140.163 1.00 73.81 ? 377 THR E OG1 1 
ATOM 2739 C CG2 . THR E 1 288 ? 193.743 154.770 140.988 1.00 73.81 ? 377 THR E CG2 1 
ATOM 2740 N N   . PHE E 1 289 ? 196.937 154.417 140.546 1.00 77.42 ? 378 PHE E N   1 
ATOM 2741 C CA  . PHE E 1 289 ? 197.973 155.317 141.071 1.00 77.42 ? 378 PHE E CA  1 
ATOM 2742 C C   . PHE E 1 289 ? 197.464 156.763 141.171 1.00 77.42 ? 378 PHE E C   1 
ATOM 2743 O O   . PHE E 1 289 ? 196.847 157.283 140.234 1.00 77.42 ? 378 PHE E O   1 
ATOM 2744 C CB  . PHE E 1 289 ? 199.226 155.230 140.191 1.00 77.42 ? 378 PHE E CB  1 
ATOM 2745 C CG  . PHE E 1 289 ? 199.868 153.861 140.198 1.00 77.42 ? 378 PHE E CG  1 
ATOM 2746 C CD1 . PHE E 1 289 ? 199.423 152.871 139.302 1.00 77.42 ? 378 PHE E CD1 1 
ATOM 2747 C CD2 . PHE E 1 289 ? 200.867 153.557 141.138 1.00 77.42 ? 378 PHE E CD2 1 
ATOM 2748 C CE1 . PHE E 1 289 ? 199.959 151.575 139.363 1.00 77.42 ? 378 PHE E CE1 1 
ATOM 2749 C CE2 . PHE E 1 289 ? 201.402 152.259 141.197 1.00 77.42 ? 378 PHE E CE2 1 
ATOM 2750 C CZ  . PHE E 1 289 ? 200.942 151.266 140.316 1.00 77.42 ? 378 PHE E CZ  1 
ATOM 2751 N N   . GLN F 1 218 ? 207.788 150.206 137.739 1.00 76.55 ? 307 GLN F N   1 
ATOM 2752 C CA  . GLN F 1 218 ? 207.502 148.941 137.076 1.00 76.55 ? 307 GLN F CA  1 
ATOM 2753 C C   . GLN F 1 218 ? 206.161 148.346 137.536 1.00 76.55 ? 307 GLN F C   1 
ATOM 2754 O O   . GLN F 1 218 ? 205.924 148.174 138.732 1.00 76.55 ? 307 GLN F O   1 
ATOM 2755 C CB  . GLN F 1 218 ? 208.681 147.983 137.318 1.00 76.55 ? 307 GLN F CB  1 
ATOM 2756 C CG  . GLN F 1 218 ? 208.488 146.595 136.688 1.00 76.55 ? 307 GLN F CG  1 
ATOM 2757 C CD  . GLN F 1 218 ? 209.688 145.669 136.869 1.00 76.55 ? 307 GLN F CD  1 
ATOM 2758 O OE1 . GLN F 1 218 ? 210.621 145.921 137.615 1.00 76.55 ? 307 GLN F OE1 1 
ATOM 2759 N NE2 . GLN F 1 218 ? 209.695 144.536 136.213 1.00 76.55 ? 307 GLN F NE2 1 
ATOM 2760 N N   . ILE F 1 219 ? 205.294 147.983 136.587 1.00 73.45 ? 308 ILE F N   1 
ATOM 2761 C CA  . ILE F 1 219 ? 204.015 147.303 136.833 1.00 73.45 ? 308 ILE F CA  1 
ATOM 2762 C C   . ILE F 1 219 ? 203.927 146.055 135.951 1.00 73.45 ? 308 ILE F C   1 
ATOM 2763 O O   . ILE F 1 219 ? 204.145 146.128 134.742 1.00 73.45 ? 308 ILE F O   1 
ATOM 2764 C CB  . ILE F 1 219 ? 202.812 148.258 136.610 1.00 73.45 ? 308 ILE F CB  1 
ATOM 2765 C CG1 . ILE F 1 219 ? 202.755 149.408 137.641 1.00 73.45 ? 308 ILE F CG1 1 
ATOM 2766 C CG2 . ILE F 1 219 ? 201.473 147.502 136.676 1.00 73.45 ? 308 ILE F CG2 1 
ATOM 2767 C CD1 . ILE F 1 219 ? 203.523 150.669 137.244 1.00 73.45 ? 308 ILE F CD1 1 
ATOM 2768 N N   . VAL F 1 220 ? 203.558 144.920 136.544 1.00 70.22 ? 309 VAL F N   1 
ATOM 2769 C CA  . VAL F 1 220 ? 203.296 143.645 135.862 1.00 70.22 ? 309 VAL F CA  1 
ATOM 2770 C C   . VAL F 1 220 ? 201.860 143.215 136.154 1.00 70.22 ? 309 VAL F C   1 
ATOM 2771 O O   . VAL F 1 220 ? 201.588 142.456 137.079 1.00 70.22 ? 309 VAL F O   1 
ATOM 2772 C CB  . VAL F 1 220 ? 204.339 142.568 136.222 1.00 70.22 ? 309 VAL F CB  1 
ATOM 2773 C CG1 . VAL F 1 220 ? 204.152 141.324 135.350 1.00 70.22 ? 309 VAL F CG1 1 
ATOM 2774 C CG2 . VAL F 1 220 ? 205.763 143.081 135.998 1.00 70.22 ? 309 VAL F CG2 1 
ATOM 2775 N N   . TYR F 1 221 ? 200.912 143.770 135.399 1.00 67.72 ? 310 TYR F N   1 
ATOM 2776 C CA  . TYR F 1 221 ? 199.489 143.453 135.512 1.00 67.72 ? 310 TYR F CA  1 
ATOM 2777 C C   . TYR F 1 221 ? 199.188 142.207 134.675 1.00 67.72 ? 310 TYR F C   1 
ATOM 2778 O O   . TYR F 1 221 ? 199.095 142.286 133.449 1.00 67.72 ? 310 TYR F O   1 
ATOM 2779 C CB  . TYR F 1 221 ? 198.679 144.678 135.068 1.00 67.72 ? 310 TYR F CB  1 
ATOM 2780 C CG  . TYR F 1 221 ? 197.190 144.626 135.354 1.00 67.72 ? 310 TYR F CG  1 
ATOM 2781 C CD1 . TYR F 1 221 ? 196.290 144.055 134.435 1.00 67.72 ? 310 TYR F CD1 1 
ATOM 2782 C CD2 . TYR F 1 221 ? 196.695 145.258 136.508 1.00 67.72 ? 310 TYR F CD2 1 
ATOM 2783 C CE1 . TYR F 1 221 ? 194.902 144.153 134.651 1.00 67.72 ? 310 TYR F CE1 1 
ATOM 2784 C CE2 . TYR F 1 221 ? 195.311 145.379 136.718 1.00 67.72 ? 310 TYR F CE2 1 
ATOM 2785 C CZ  . TYR F 1 221 ? 194.412 144.846 135.777 1.00 67.72 ? 310 TYR F CZ  1 
ATOM 2786 O OH  . TYR F 1 221 ? 193.082 145.042 135.948 1.00 67.72 ? 310 TYR F OH  1 
ATOM 2787 N N   . LYS F 1 222 ? 199.087 141.039 135.314 1.00 64.86 ? 311 LYS F N   1 
ATOM 2788 C CA  . LYS F 1 222 ? 198.985 139.742 134.624 1.00 64.86 ? 311 LYS F CA  1 
ATOM 2789 C C   . LYS F 1 222 ? 198.037 138.752 135.329 1.00 64.86 ? 311 LYS F C   1 
ATOM 2790 O O   . LYS F 1 222 ? 198.458 137.663 135.703 1.00 64.86 ? 311 LYS F O   1 
ATOM 2791 C CB  . LYS F 1 222 ? 200.413 139.210 134.392 1.00 64.86 ? 311 LYS F CB  1 
ATOM 2792 C CG  . LYS F 1 222 ? 200.464 138.141 133.294 1.00 64.86 ? 311 LYS F CG  1 
ATOM 2793 C CD  . LYS F 1 222 ? 201.902 137.715 132.994 1.00 64.86 ? 311 LYS F CD  1 
ATOM 2794 C CE  . LYS F 1 222 ? 201.901 136.700 131.848 1.00 64.86 ? 311 LYS F CE  1 
ATOM 2795 N NZ  . LYS F 1 222 ? 203.271 136.250 131.514 1.00 64.86 ? 311 LYS F NZ  1 
ATOM 2796 N N   . PRO F 1 223 ? 196.756 139.100 135.546 1.00 62.91 ? 312 PRO F N   1 
ATOM 2797 C CA  . PRO F 1 223 ? 195.783 138.170 136.115 1.00 62.91 ? 312 PRO F CA  1 
ATOM 2798 C C   . PRO F 1 223 ? 195.596 136.924 135.235 1.00 62.91 ? 312 PRO F C   1 
ATOM 2799 O O   . PRO F 1 223 ? 195.691 137.009 134.011 1.00 62.91 ? 312 PRO F O   1 
ATOM 2800 C CB  . PRO F 1 223 ? 194.492 138.989 136.236 1.00 62.91 ? 312 PRO F CB  1 
ATOM 2801 C CG  . PRO F 1 223 ? 194.614 140.039 135.139 1.00 62.91 ? 312 PRO F CG  1 
ATOM 2802 C CD  . PRO F 1 223 ? 196.107 140.338 135.142 1.00 62.91 ? 312 PRO F CD  1 
ATOM 2803 N N   . VAL F 1 224 ? 195.280 135.774 135.838 1.00 61.15 ? 313 VAL F N   1 
ATOM 2804 C CA  . VAL F 1 224 ? 195.012 134.510 135.130 1.00 61.15 ? 313 VAL F CA  1 
ATOM 2805 C C   . VAL F 1 224 ? 193.653 133.945 135.531 1.00 61.15 ? 313 VAL F C   1 
ATOM 2806 O O   . VAL F 1 224 ? 193.358 133.771 136.710 1.00 61.15 ? 313 VAL F O   1 
ATOM 2807 C CB  . VAL F 1 224 ? 196.135 133.486 135.384 1.00 61.15 ? 313 VAL F CB  1 
ATOM 2808 C CG1 . VAL F 1 224 ? 195.842 132.112 134.775 1.00 61.15 ? 313 VAL F CG1 1 
ATOM 2809 C CG2 . VAL F 1 224 ? 197.466 133.976 134.808 1.00 61.15 ? 313 VAL F CG2 1 
ATOM 2810 N N   . ASP F 1 225 ? 192.815 133.632 134.548 1.00 59.09 ? 314 ASP F N   1 
ATOM 2811 C CA  . ASP F 1 225 ? 191.501 133.016 134.742 1.00 59.09 ? 314 ASP F CA  1 
ATOM 2812 C C   . ASP F 1 225 ? 191.392 131.707 133.953 1.00 59.09 ? 314 ASP F C   1 
ATOM 2813 O O   . ASP F 1 225 ? 191.591 131.678 132.741 1.00 59.09 ? 314 ASP F O   1 
ATOM 2814 C CB  . ASP F 1 225 ? 190.418 134.022 134.329 1.00 59.09 ? 314 ASP F CB  1 
ATOM 2815 C CG  . ASP F 1 225 ? 188.991 133.470 134.434 1.00 59.09 ? 314 ASP F CG  1 
ATOM 2816 O OD1 . ASP F 1 225 ? 188.766 132.423 135.078 1.00 59.09 ? 314 ASP F OD1 1 
ATOM 2817 O OD2 . ASP F 1 225 ? 188.082 134.064 133.818 1.00 59.09 ? 314 ASP F OD2 1 
ATOM 2818 N N   . LEU F 1 226 ? 191.048 130.630 134.652 1.00 57.53 ? 315 LEU F N   1 
ATOM 2819 C CA  . LEU F 1 226 ? 190.860 129.274 134.142 1.00 57.53 ? 315 LEU F CA  1 
ATOM 2820 C C   . LEU F 1 226 ? 189.506 128.690 134.599 1.00 57.53 ? 315 LEU F C   1 
ATOM 2821 O O   . LEU F 1 226 ? 189.258 127.492 134.470 1.00 57.53 ? 315 LEU F O   1 
ATOM 2822 C CB  . LEU F 1 226 ? 192.068 128.431 134.589 1.00 57.53 ? 315 LEU F CB  1 
ATOM 2823 C CG  . LEU F 1 226 ? 193.427 128.892 134.028 1.00 57.53 ? 315 LEU F CG  1 
ATOM 2824 C CD1 . LEU F 1 226 ? 194.570 128.274 134.820 1.00 57.53 ? 315 LEU F CD1 1 
ATOM 2825 C CD2 . LEU F 1 226 ? 193.593 128.508 132.563 1.00 57.53 ? 315 LEU F CD2 1 
ATOM 2826 N N   . SER F 1 227 ? 188.636 129.517 135.183 1.00 56.45 ? 316 SER F N   1 
ATOM 2827 C CA  . SER F 1 227 ? 187.354 129.140 135.796 1.00 56.45 ? 316 SER F CA  1 
ATOM 2828 C C   . SER F 1 227 ? 186.281 128.635 134.815 1.00 56.45 ? 316 SER F C   1 
ATOM 2829 O O   . SER F 1 227 ? 186.375 128.869 133.611 1.00 56.45 ? 316 SER F O   1 
ATOM 2830 C CB  . SER F 1 227 ? 186.839 130.330 136.599 1.00 56.45 ? 316 SER F CB  1 
ATOM 2831 O OG  . SER F 1 227 ? 186.517 131.407 135.747 1.00 56.45 ? 316 SER F OG  1 
ATOM 2832 N N   . LYS F 1 228 ? 185.245 127.944 135.319 1.00 54.52 ? 317 LYS F N   1 
ATOM 2833 C CA  . LYS F 1 228 ? 184.122 127.396 134.519 1.00 54.52 ? 317 LYS F CA  1 
ATOM 2834 C C   . LYS F 1 228 ? 182.741 127.756 135.087 1.00 54.52 ? 317 LYS F C   1 
ATOM 2835 O O   . LYS F 1 228 ? 182.552 127.732 136.303 1.00 54.52 ? 317 LYS F O   1 
ATOM 2836 C CB  . LYS F 1 228 ? 184.234 125.864 134.397 1.00 54.52 ? 317 LYS F CB  1 
ATOM 2837 C CG  . LYS F 1 228 ? 185.534 125.333 133.772 1.00 54.52 ? 317 LYS F CG  1 
ATOM 2838 C CD  . LYS F 1 228 ? 185.659 125.666 132.279 1.00 54.52 ? 317 LYS F CD  1 
ATOM 2839 C CE  . LYS F 1 228 ? 186.890 125.014 131.630 1.00 54.52 ? 317 LYS F CE  1 
ATOM 2840 N NZ  . LYS F 1 228 ? 188.148 125.771 131.858 1.00 54.52 ? 317 LYS F NZ  1 
ATOM 2841 N N   . VAL F 1 229 ? 181.770 128.031 134.214 1.00 52.89 ? 318 VAL F N   1 
ATOM 2842 C CA  . VAL F 1 229 ? 180.337 128.128 134.545 1.00 52.89 ? 318 VAL F CA  1 
ATOM 2843 C C   . VAL F 1 229 ? 179.565 127.145 133.658 1.00 52.89 ? 318 VAL F C   1 
ATOM 2844 O O   . VAL F 1 229 ? 179.665 127.219 132.437 1.00 52.89 ? 318 VAL F O   1 
ATOM 2845 C CB  . VAL F 1 229 ? 179.806 129.569 134.406 1.00 52.89 ? 318 VAL F CB  1 
ATOM 2846 C CG1 . VAL F 1 229 ? 178.361 129.679 134.906 1.00 52.89 ? 318 VAL F CG1 1 
ATOM 2847 C CG2 . VAL F 1 229 ? 180.640 130.585 135.192 1.00 52.89 ? 318 VAL F CG2 1 
ATOM 2848 N N   . THR F 1 230 ? 178.811 126.213 134.242 1.00 52.42 ? 319 THR F N   1 
ATOM 2849 C CA  . THR F 1 230 ? 178.309 125.013 133.537 1.00 52.42 ? 319 THR F CA  1 
ATOM 2850 C C   . THR F 1 230 ? 176.901 124.628 133.995 1.00 52.42 ? 319 THR F C   1 
ATOM 2851 O O   . THR F 1 230 ? 176.523 124.884 135.137 1.00 52.42 ? 319 THR F O   1 
ATOM 2852 C CB  . THR F 1 230 ? 179.300 123.854 133.766 1.00 52.42 ? 319 THR F CB  1 
ATOM 2853 O OG1 . THR F 1 230 ? 180.547 124.158 133.187 1.00 52.42 ? 319 THR F OG1 1 
ATOM 2854 C CG2 . THR F 1 230 ? 178.883 122.504 133.186 1.00 52.42 ? 319 THR F CG2 1 
ATOM 2855 N N   . SER F 1 231 ? 176.090 123.987 133.150 1.00 49.96 ? 320 SER F N   1 
ATOM 2856 C CA  . SER F 1 231 ? 174.824 123.358 133.571 1.00 49.96 ? 320 SER F CA  1 
ATOM 2857 C C   . SER F 1 231 ? 174.442 122.135 132.744 1.00 49.96 ? 320 SER F C   1 
ATOM 2858 O O   . SER F 1 231 ? 174.750 122.064 131.558 1.00 49.96 ? 320 SER F O   1 
ATOM 2859 C CB  . SER F 1 231 ? 173.665 124.354 133.506 1.00 49.96 ? 320 SER F CB  1 
ATOM 2860 O OG  . SER F 1 231 ? 173.982 125.484 134.290 1.00 49.96 ? 320 SER F OG  1 
ATOM 2861 N N   . LYS F 1 232 ? 173.689 121.222 133.362 1.00 48.44 ? 321 LYS F N   1 
ATOM 2862 C CA  . LYS F 1 232 ? 172.911 120.172 132.696 1.00 48.44 ? 321 LYS F CA  1 
ATOM 2863 C C   . LYS F 1 232 ? 171.461 120.225 133.161 1.00 48.44 ? 321 LYS F C   1 
ATOM 2864 O O   . LYS F 1 232 ? 171.196 120.367 134.352 1.00 48.44 ? 321 LYS F O   1 
ATOM 2865 C CB  . LYS F 1 232 ? 173.519 118.785 132.951 1.00 48.44 ? 321 LYS F CB  1 
ATOM 2866 C CG  . LYS F 1 232 ? 174.883 118.612 132.277 1.00 48.44 ? 321 LYS F CG  1 
ATOM 2867 C CD  . LYS F 1 232 ? 175.360 117.160 132.379 1.00 48.44 ? 321 LYS F CD  1 
ATOM 2868 C CE  . LYS F 1 232 ? 176.693 116.993 131.645 1.00 48.44 ? 321 LYS F CE  1 
ATOM 2869 N NZ  . LYS F 1 232 ? 177.105 115.574 131.572 1.00 48.44 ? 321 LYS F NZ  1 
ATOM 2870 N N   . CYS F 1 233 ? 170.526 120.093 132.228 1.00 47.95 ? 322 CYS F N   1 
ATOM 2871 C CA  . CYS F 1 233 ? 169.094 120.001 132.487 1.00 47.95 ? 322 CYS F CA  1 
ATOM 2872 C C   . CYS F 1 233 ? 168.503 118.858 131.647 1.00 47.95 ? 322 CYS F C   1 
ATOM 2873 O O   . CYS F 1 233 ? 168.712 118.806 130.434 1.00 47.95 ? 322 CYS F O   1 
ATOM 2874 C CB  . CYS F 1 233 ? 168.462 121.371 132.202 1.00 47.95 ? 322 CYS F CB  1 
ATOM 2875 S SG  . CYS F 1 233 ? 166.686 121.362 132.563 1.00 47.95 ? 322 CYS F SG  1 
ATOM 2876 N N   . GLY F 1 234 ? 167.784 117.924 132.268 1.00 46.19 ? 323 GLY F N   1 
ATOM 2877 C CA  . GLY F 1 234 ? 167.343 116.693 131.599 1.00 46.19 ? 323 GLY F CA  1 
ATOM 2878 C C   . GLY F 1 234 ? 166.168 116.867 130.633 1.00 46.19 ? 323 GLY F C   1 
ATOM 2879 O O   . GLY F 1 234 ? 166.100 116.202 129.599 1.00 46.19 ? 323 GLY F O   1 
ATOM 2880 N N   . SER F 1 235 ? 165.246 117.772 130.952 1.00 44.59 ? 324 SER F N   1 
ATOM 2881 C CA  . SER F 1 235 ? 164.102 118.156 130.120 1.00 44.59 ? 324 SER F CA  1 
ATOM 2882 C C   . SER F 1 235 ? 163.517 119.469 130.631 1.00 44.59 ? 324 SER F C   1 
ATOM 2883 O O   . SER F 1 235 ? 163.457 119.675 131.840 1.00 44.59 ? 324 SER F O   1 
ATOM 2884 C CB  . SER F 1 235 ? 163.026 117.073 130.136 1.00 44.59 ? 324 SER F CB  1 
ATOM 2885 O OG  . SER F 1 235 ? 161.977 117.439 129.267 1.00 44.59 ? 324 SER F OG  1 
ATOM 2886 N N   . LEU F 1 236 ? 163.121 120.364 129.731 1.00 42.17 ? 325 LEU F N   1 
ATOM 2887 C CA  . LEU F 1 236 ? 162.649 121.714 130.046 1.00 42.17 ? 325 LEU F CA  1 
ATOM 2888 C C   . LEU F 1 236 ? 161.373 122.015 129.249 1.00 42.17 ? 325 LEU F C   1 
ATOM 2889 O O   . LEU F 1 236 ? 161.416 122.031 128.021 1.00 42.17 ? 325 LEU F O   1 
ATOM 2890 C CB  . LEU F 1 236 ? 163.816 122.687 129.775 1.00 42.17 ? 325 LEU F CB  1 
ATOM 2891 C CG  . LEU F 1 236 ? 163.516 124.183 129.951 1.00 42.17 ? 325 LEU F CG  1 
ATOM 2892 C CD1 . LEU F 1 236 ? 163.016 124.515 131.346 1.00 42.17 ? 325 LEU F CD1 1 
ATOM 2893 C CD2 . LEU F 1 236 ? 164.786 124.992 129.716 1.00 42.17 ? 325 LEU F CD2 1 
ATOM 2894 N N   . GLY F 1 237 ? 160.234 122.239 129.904 1.00 37.85 ? 326 GLY F N   1 
ATOM 2895 C CA  . GLY F 1 237 ? 158.972 122.482 129.194 1.00 37.85 ? 326 GLY F CA  1 
ATOM 2896 C C   . GLY F 1 237 ? 157.715 122.450 130.056 1.00 37.85 ? 326 GLY F C   1 
ATOM 2897 O O   . GLY F 1 237 ? 157.791 122.461 131.277 1.00 37.85 ? 326 GLY F O   1 
ATOM 2898 N N   . ASN F 1 238 ? 156.542 122.426 129.418 1.00 35.20 ? 327 ASN F N   1 
ATOM 2899 C CA  . ASN F 1 238 ? 155.218 122.532 130.051 1.00 35.20 ? 327 ASN F CA  1 
ATOM 2900 C C   . ASN F 1 238 ? 155.076 123.811 130.900 1.00 35.20 ? 327 ASN F C   1 
ATOM 2901 O O   . ASN F 1 238 ? 154.823 123.761 132.100 1.00 35.20 ? 327 ASN F O   1 
ATOM 2902 C CB  . ASN F 1 238 ? 154.876 121.214 130.772 1.00 35.20 ? 327 ASN F CB  1 
ATOM 2903 C CG  . ASN F 1 238 ? 153.426 121.116 131.211 1.00 35.20 ? 327 ASN F CG  1 
ATOM 2904 O OD1 . ASN F 1 238 ? 152.535 121.764 130.685 1.00 35.20 ? 327 ASN F OD1 1 
ATOM 2905 N ND2 . ASN F 1 238 ? 153.133 120.283 132.177 1.00 35.20 ? 327 ASN F ND2 1 
ATOM 2906 N N   . ILE F 1 239 ? 155.324 124.963 130.273 1.00 33.72 ? 328 ILE F N   1 
ATOM 2907 C CA  . ILE F 1 239 ? 155.295 126.297 130.885 1.00 33.72 ? 328 ILE F CA  1 
ATOM 2908 C C   . ILE F 1 239 ? 154.153 127.121 130.272 1.00 33.72 ? 328 ILE F C   1 
ATOM 2909 O O   . ILE F 1 239 ? 154.077 127.262 129.055 1.00 33.72 ? 328 ILE F O   1 
ATOM 2910 C CB  . ILE F 1 239 ? 156.675 126.975 130.736 1.00 33.72 ? 328 ILE F CB  1 
ATOM 2911 C CG1 . ILE F 1 239 ? 157.763 126.224 131.537 1.00 33.72 ? 328 ILE F CG1 1 
ATOM 2912 C CG2 . ILE F 1 239 ? 156.643 128.437 131.201 1.00 33.72 ? 328 ILE F CG2 1 
ATOM 2913 C CD1 . ILE F 1 239 ? 159.154 126.336 130.923 1.00 33.72 ? 328 ILE F CD1 1 
ATOM 2914 N N   . HIS F 1 240 ? 153.267 127.674 131.099 1.00 32.73 ? 329 HIS F N   1 
ATOM 2915 C CA  . HIS F 1 240 ? 152.099 128.456 130.680 1.00 32.73 ? 329 HIS F CA  1 
ATOM 2916 C C   . HIS F 1 240 ? 152.145 129.853 131.289 1.00 32.73 ? 329 HIS F C   1 
ATOM 2917 O O   . HIS F 1 240 ? 152.148 129.983 132.508 1.00 32.73 ? 329 HIS F O   1 
ATOM 2918 C CB  . HIS F 1 240 ? 150.816 127.723 131.102 1.00 32.73 ? 329 HIS F CB  1 
ATOM 2919 C CG  . HIS F 1 240 ? 150.697 126.321 130.564 1.00 32.73 ? 329 HIS F CG  1 
ATOM 2920 N ND1 . HIS F 1 240 ? 150.113 125.962 129.349 1.00 32.73 ? 329 HIS F ND1 1 
ATOM 2921 C CD2 . HIS F 1 240 ? 151.262 125.213 131.119 1.00 32.73 ? 329 HIS F CD2 1 
ATOM 2922 C CE1 . HIS F 1 240 ? 150.334 124.645 129.211 1.00 32.73 ? 329 HIS F CE1 1 
ATOM 2923 N NE2 . HIS F 1 240 ? 151.015 124.171 130.262 1.00 32.73 ? 329 HIS F NE2 1 
ATOM 2924 N N   . HIS F 1 241 ? 152.151 130.903 130.473 1.00 31.87 ? 330 HIS F N   1 
ATOM 2925 C CA  . HIS F 1 241 ? 152.056 132.300 130.908 1.00 31.87 ? 330 HIS F CA  1 
ATOM 2926 C C   . HIS F 1 241 ? 150.817 132.939 130.277 1.00 31.87 ? 330 HIS F C   1 
ATOM 2927 O O   . HIS F 1 241 ? 150.748 133.057 129.057 1.00 31.87 ? 330 HIS F O   1 
ATOM 2928 C CB  . HIS F 1 241 ? 153.358 133.017 130.531 1.00 31.87 ? 330 HIS F CB  1 
ATOM 2929 C CG  . HIS F 1 241 ? 153.508 134.455 130.974 1.00 31.87 ? 330 HIS F CG  1 
ATOM 2930 N ND1 . HIS F 1 241 ? 154.452 135.322 130.485 1.00 31.87 ? 330 HIS F ND1 1 
ATOM 2931 C CD2 . HIS F 1 241 ? 152.910 135.088 132.029 1.00 31.87 ? 330 HIS F CD2 1 
ATOM 2932 C CE1 . HIS F 1 241 ? 154.419 136.450 131.200 1.00 31.87 ? 330 HIS F CE1 1 
ATOM 2933 N NE2 . HIS F 1 241 ? 153.506 136.345 132.171 1.00 31.87 ? 330 HIS F NE2 1 
ATOM 2934 N N   . LYS F 1 242 ? 149.827 133.333 131.085 1.00 31.36 ? 331 LYS F N   1 
ATOM 2935 C CA  . LYS F 1 242 ? 148.491 133.751 130.616 1.00 31.36 ? 331 LYS F CA  1 
ATOM 2936 C C   . LYS F 1 242 ? 147.961 134.986 131.357 1.00 31.36 ? 331 LYS F C   1 
ATOM 2937 O O   . LYS F 1 242 ? 147.133 134.840 132.254 1.00 31.36 ? 331 LYS F O   1 
ATOM 2938 C CB  . LYS F 1 242 ? 147.508 132.569 130.720 1.00 31.36 ? 331 LYS F CB  1 
ATOM 2939 C CG  . LYS F 1 242 ? 147.797 131.440 129.726 1.00 31.36 ? 331 LYS F CG  1 
ATOM 2940 C CD  . LYS F 1 242 ? 147.002 130.163 130.010 1.00 31.36 ? 331 LYS F CD  1 
ATOM 2941 C CE  . LYS F 1 242 ? 145.500 130.378 129.802 1.00 31.36 ? 331 LYS F CE  1 
ATOM 2942 N NZ  . LYS F 1 242 ? 144.746 129.109 129.912 1.00 31.36 ? 331 LYS F NZ  1 
ATOM 2943 N N   . PRO F 1 243 ? 148.424 136.204 131.039 1.00 30.95 ? 332 PRO F N   1 
ATOM 2944 C CA  . PRO F 1 243 ? 147.982 137.427 131.709 1.00 30.95 ? 332 PRO F CA  1 
ATOM 2945 C C   . PRO F 1 243 ? 146.567 137.867 131.330 1.00 30.95 ? 332 PRO F C   1 
ATOM 2946 O O   . PRO F 1 243 ? 146.144 137.742 130.184 1.00 30.95 ? 332 PRO F O   1 
ATOM 2947 C CB  . PRO F 1 243 ? 149.026 138.494 131.363 1.00 30.95 ? 332 PRO F CB  1 
ATOM 2948 C CG  . PRO F 1 243 ? 150.207 137.693 130.829 1.00 30.95 ? 332 PRO F CG  1 
ATOM 2949 C CD  . PRO F 1 243 ? 149.534 136.510 130.164 1.00 30.95 ? 332 PRO F CD  1 
ATOM 2950 N N   . GLY F 1 244 ? 145.838 138.407 132.303 1.00 30.56 ? 333 GLY F N   1 
ATOM 2951 C CA  . GLY F 1 244 ? 144.452 138.863 132.199 1.00 30.56 ? 333 GLY F CA  1 
ATOM 2952 C C   . GLY F 1 244 ? 144.284 140.362 131.962 1.00 30.56 ? 333 GLY F C   1 
ATOM 2953 O O   . GLY F 1 244 ? 143.486 141.002 132.642 1.00 30.56 ? 333 GLY F O   1 
ATOM 2954 N N   . GLY F 1 245 ? 145.052 140.955 131.053 1.00 30.30 ? 334 GLY F N   1 
ATOM 2955 C CA  . GLY F 1 245 ? 144.917 142.365 130.670 1.00 30.30 ? 334 GLY F CA  1 
ATOM 2956 C C   . GLY F 1 245 ? 145.392 143.348 131.738 1.00 30.30 ? 334 GLY F C   1 
ATOM 2957 O O   . GLY F 1 245 ? 146.405 143.123 132.391 1.00 30.30 ? 334 GLY F O   1 
ATOM 2958 N N   . GLY F 1 246 ? 144.668 144.450 131.917 1.00 30.81 ? 335 GLY F N   1 
ATOM 2959 C CA  . GLY F 1 246 ? 144.994 145.529 132.855 1.00 30.81 ? 335 GLY F CA  1 
ATOM 2960 C C   . GLY F 1 246 ? 144.886 146.917 132.226 1.00 30.81 ? 335 GLY F C   1 
ATOM 2961 O O   . GLY F 1 246 ? 144.574 147.046 131.045 1.00 30.81 ? 335 GLY F O   1 
ATOM 2962 N N   . GLN F 1 247 ? 145.119 147.972 133.004 1.00 32.29 ? 336 GLN F N   1 
ATOM 2963 C CA  . GLN F 1 247 ? 145.047 149.347 132.503 1.00 32.29 ? 336 GLN F CA  1 
ATOM 2964 C C   . GLN F 1 247 ? 146.076 150.297 133.127 1.00 32.29 ? 336 GLN F C   1 
ATOM 2965 O O   . GLN F 1 247 ? 146.297 150.264 134.334 1.00 32.29 ? 336 GLN F O   1 
ATOM 2966 C CB  . GLN F 1 247 ? 143.607 149.827 132.692 1.00 32.29 ? 336 GLN F CB  1 
ATOM 2967 C CG  . GLN F 1 247 ? 143.318 151.128 131.952 1.00 32.29 ? 336 GLN F CG  1 
ATOM 2968 C CD  . GLN F 1 247 ? 141.826 151.281 131.761 1.00 32.29 ? 336 GLN F CD  1 
ATOM 2969 O OE1 . GLN F 1 247 ? 141.133 151.719 132.649 1.00 32.29 ? 336 GLN F OE1 1 
ATOM 2970 N NE2 . GLN F 1 247 ? 141.275 150.916 130.635 1.00 32.29 ? 336 GLN F NE2 1 
ATOM 2971 N N   . VAL F 1 248 ? 146.684 151.165 132.320 1.00 34.23 ? 337 VAL F N   1 
ATOM 2972 C CA  . VAL F 1 248 ? 147.724 152.119 132.747 1.00 34.23 ? 337 VAL F CA  1 
ATOM 2973 C C   . VAL F 1 248 ? 147.443 153.516 132.190 1.00 34.23 ? 337 VAL F C   1 
ATOM 2974 O O   . VAL F 1 248 ? 147.135 153.654 131.010 1.00 34.23 ? 337 VAL F O   1 
ATOM 2975 C CB  . VAL F 1 248 ? 149.136 151.631 132.349 1.00 34.23 ? 337 VAL F CB  1 
ATOM 2976 C CG1 . VAL F 1 248 ? 150.235 152.593 132.811 1.00 34.23 ? 337 VAL F CG1 1 
ATOM 2977 C CG2 . VAL F 1 248 ? 149.450 150.255 132.945 1.00 34.23 ? 337 VAL F CG2 1 
ATOM 2978 N N   . GLU F 1 249 ? 147.579 154.556 133.011 1.00 37.82 ? 338 GLU F N   1 
ATOM 2979 C CA  . GLU F 1 249 ? 147.475 155.967 132.613 1.00 37.82 ? 338 GLU F CA  1 
ATOM 2980 C C   . GLU F 1 249 ? 148.601 156.826 133.204 1.00 37.82 ? 338 GLU F C   1 
ATOM 2981 O O   . GLU F 1 249 ? 148.886 156.742 134.395 1.00 37.82 ? 338 GLU F O   1 
ATOM 2982 C CB  . GLU F 1 249 ? 146.093 156.499 133.016 1.00 37.82 ? 338 GLU F CB  1 
ATOM 2983 C CG  . GLU F 1 249 ? 145.900 157.985 132.677 1.00 37.82 ? 338 GLU F CG  1 
ATOM 2984 C CD  . GLU F 1 249 ? 144.465 158.485 132.903 1.00 37.82 ? 338 GLU F CD  1 
ATOM 2985 O OE1 . GLU F 1 249 ? 143.514 157.672 132.968 1.00 37.82 ? 338 GLU F OE1 1 
ATOM 2986 O OE2 . GLU F 1 249 ? 144.273 159.719 132.987 1.00 37.82 ? 338 GLU F OE2 1 
ATOM 2987 N N   . VAL F 1 250 ? 149.214 157.696 132.393 1.00 39.64 ? 339 VAL F N   1 
ATOM 2988 C CA  . VAL F 1 250 ? 150.244 158.653 132.830 1.00 39.64 ? 339 VAL F CA  1 
ATOM 2989 C C   . VAL F 1 250 ? 149.976 160.044 132.246 1.00 39.64 ? 339 VAL F C   1 
ATOM 2990 O O   . VAL F 1 250 ? 149.679 160.163 131.060 1.00 39.64 ? 339 VAL F O   1 
ATOM 2991 C CB  . VAL F 1 250 ? 151.671 158.172 132.486 1.00 39.64 ? 339 VAL F CB  1 
ATOM 2992 C CG1 . VAL F 1 250 ? 152.719 159.112 133.091 1.00 39.64 ? 339 VAL F CG1 1 
ATOM 2993 C CG2 . VAL F 1 250 ? 151.966 156.761 133.006 1.00 39.64 ? 339 VAL F CG2 1 
ATOM 2994 N N   . LYS F 1 251 ? 150.123 161.103 133.050 1.00 43.73 ? 340 LYS F N   1 
ATOM 2995 C CA  . LYS F 1 251 ? 150.008 162.512 132.633 1.00 43.73 ? 340 LYS F CA  1 
ATOM 2996 C C   . LYS F 1 251 ? 151.228 163.336 133.065 1.00 43.73 ? 340 LYS F C   1 
ATOM 2997 O O   . LYS F 1 251 ? 151.686 163.204 134.195 1.00 43.73 ? 340 LYS F O   1 
ATOM 2998 C CB  . LYS F 1 251 ? 148.683 163.075 133.175 1.00 43.73 ? 340 LYS F CB  1 
ATOM 2999 C CG  . LYS F 1 251 ? 148.434 164.514 132.699 1.00 43.73 ? 340 LYS F CG  1 
ATOM 3000 C CD  . LYS F 1 251 ? 147.068 165.087 133.097 1.00 43.73 ? 340 LYS F CD  1 
ATOM 3001 C CE  . LYS F 1 251 ? 145.909 164.366 132.397 1.00 43.73 ? 340 LYS F CE  1 
ATOM 3002 N NZ  . LYS F 1 251 ? 144.609 165.028 132.659 1.00 43.73 ? 340 LYS F NZ  1 
ATOM 3003 N N   . SER F 1 252 ? 151.739 164.183 132.169 1.00 48.33 ? 341 SER F N   1 
ATOM 3004 C CA  . SER F 1 252 ? 152.842 165.141 132.382 1.00 48.33 ? 341 SER F CA  1 
ATOM 3005 C C   . SER F 1 252 ? 152.627 166.427 131.576 1.00 48.33 ? 341 SER F C   1 
ATOM 3006 O O   . SER F 1 252 ? 151.985 166.391 130.526 1.00 48.33 ? 341 SER F O   1 
ATOM 3007 C CB  . SER F 1 252 ? 154.180 164.527 131.958 1.00 48.33 ? 341 SER F CB  1 
ATOM 3008 O OG  . SER F 1 252 ? 154.520 163.445 132.799 1.00 48.33 ? 341 SER F OG  1 
ATOM 3009 N N   . GLU F 1 253 ? 153.207 167.554 131.996 1.00 51.70 ? 342 GLU F N   1 
ATOM 3010 C CA  . GLU F 1 253 ? 153.324 168.754 131.154 1.00 51.70 ? 342 GLU F CA  1 
ATOM 3011 C C   . GLU F 1 253 ? 154.643 168.777 130.370 1.00 51.70 ? 342 GLU F C   1 
ATOM 3012 O O   . GLU F 1 253 ? 154.617 169.028 129.166 1.00 51.70 ? 342 GLU F O   1 
ATOM 3013 C CB  . GLU F 1 253 ? 153.170 170.057 131.962 1.00 51.70 ? 342 GLU F CB  1 
ATOM 3014 C CG  . GLU F 1 253 ? 151.886 170.151 132.801 1.00 51.70 ? 342 GLU F CG  1 
ATOM 3015 C CD  . GLU F 1 253 ? 150.588 170.175 131.974 1.00 51.70 ? 342 GLU F CD  1 
ATOM 3016 O OE1 . GLU F 1 253 ? 150.597 170.621 130.803 1.00 51.70 ? 342 GLU F OE1 1 
ATOM 3017 O OE2 . GLU F 1 253 ? 149.529 169.761 132.497 1.00 51.70 ? 342 GLU F OE2 1 
ATOM 3018 N N   . LYS F 1 254 ? 155.793 168.515 131.013 1.00 51.77 ? 343 LYS F N   1 
ATOM 3019 C CA  . LYS F 1 254 ? 157.122 168.616 130.373 1.00 51.77 ? 343 LYS F CA  1 
ATOM 3020 C C   . LYS F 1 254 ? 158.083 167.485 130.735 1.00 51.77 ? 343 LYS F C   1 
ATOM 3021 O O   . LYS F 1 254 ? 158.161 167.072 131.887 1.00 51.77 ? 343 LYS F O   1 
ATOM 3022 C CB  . LYS F 1 254 ? 157.782 169.971 130.686 1.00 51.77 ? 343 LYS F CB  1 
ATOM 3023 C CG  . LYS F 1 254 ? 156.996 171.163 130.132 1.00 51.77 ? 343 LYS F CG  1 
ATOM 3024 C CD  . LYS F 1 254 ? 157.828 172.447 130.203 1.00 51.77 ? 343 LYS F CD  1 
ATOM 3025 C CE  . LYS F 1 254 ? 157.035 173.615 129.610 1.00 51.77 ? 343 LYS F CE  1 
ATOM 3026 N NZ  . LYS F 1 254 ? 157.857 174.845 129.523 1.00 51.77 ? 343 LYS F NZ  1 
ATOM 3027 N N   . LEU F 1 255 ? 158.862 167.050 129.747 1.00 51.04 ? 344 LEU F N   1 
ATOM 3028 C CA  . LEU F 1 255 ? 159.970 166.101 129.868 1.00 51.04 ? 344 LEU F CA  1 
ATOM 3029 C C   . LEU F 1 255 ? 161.258 166.772 129.386 1.00 51.04 ? 344 LEU F C   1 
ATOM 3030 O O   . LEU F 1 255 ? 161.264 167.391 128.324 1.00 51.04 ? 344 LEU F O   1 
ATOM 3031 C CB  . LEU F 1 255 ? 159.699 164.857 129.000 1.00 51.04 ? 344 LEU F CB  1 
ATOM 3032 C CG  . LEU F 1 255 ? 158.350 164.153 129.212 1.00 51.04 ? 344 LEU F CG  1 
ATOM 3033 C CD1 . LEU F 1 255 ? 158.235 162.965 128.266 1.00 51.04 ? 344 LEU F CD1 1 
ATOM 3034 C CD2 . LEU F 1 255 ? 158.219 163.628 130.628 1.00 51.04 ? 344 LEU F CD2 1 
ATOM 3035 N N   . ASP F 1 256 ? 162.359 166.633 130.116 1.00 51.16 ? 345 ASP F N   1 
ATOM 3036 C CA  . ASP F 1 256 ? 163.662 167.169 129.707 1.00 51.16 ? 345 ASP F CA  1 
ATOM 3037 C C   . ASP F 1 256 ? 164.796 166.233 130.154 1.00 51.16 ? 345 ASP F C   1 
ATOM 3038 O O   . ASP F 1 256 ? 165.181 166.219 131.318 1.00 51.16 ? 345 ASP F O   1 
ATOM 3039 C CB  . ASP F 1 256 ? 163.802 168.598 130.257 1.00 51.16 ? 345 ASP F CB  1 
ATOM 3040 C CG  . ASP F 1 256 ? 165.014 169.352 129.703 1.00 51.16 ? 345 ASP F CG  1 
ATOM 3041 O OD1 . ASP F 1 256 ? 165.768 168.794 128.881 1.00 51.16 ? 345 ASP F OD1 1 
ATOM 3042 O OD2 . ASP F 1 256 ? 165.179 170.541 130.051 1.00 51.16 ? 345 ASP F OD2 1 
ATOM 3043 N N   . PHE F 1 257 ? 165.289 165.387 129.249 1.00 48.98 ? 346 PHE F N   1 
ATOM 3044 C CA  . PHE F 1 257 ? 166.280 164.350 129.547 1.00 48.98 ? 346 PHE F CA  1 
ATOM 3045 C C   . PHE F 1 257 ? 167.625 164.677 128.881 1.00 48.98 ? 346 PHE F C   1 
ATOM 3046 O O   . PHE F 1 257 ? 167.660 164.936 127.678 1.00 48.98 ? 346 PHE F O   1 
ATOM 3047 C CB  . PHE F 1 257 ? 165.751 162.978 129.098 1.00 48.98 ? 346 PHE F CB  1 
ATOM 3048 C CG  . PHE F 1 257 ? 164.427 162.488 129.675 1.00 48.98 ? 346 PHE F CG  1 
ATOM 3049 C CD1 . PHE F 1 257 ? 163.850 163.058 130.826 1.00 48.98 ? 346 PHE F CD1 1 
ATOM 3050 C CD2 . PHE F 1 257 ? 163.744 161.448 129.019 1.00 48.98 ? 346 PHE F CD2 1 
ATOM 3051 C CE1 . PHE F 1 257 ? 162.590 162.642 131.277 1.00 48.98 ? 346 PHE F CE1 1 
ATOM 3052 C CE2 . PHE F 1 257 ? 162.481 161.031 129.470 1.00 48.98 ? 346 PHE F CE2 1 
ATOM 3053 C CZ  . PHE F 1 257 ? 161.897 161.638 130.592 1.00 48.98 ? 346 PHE F CZ  1 
ATOM 3054 N N   . LYS F 1 258 ? 168.734 164.654 129.632 1.00 49.85 ? 347 LYS F N   1 
ATOM 3055 C CA  . LYS F 1 258 ? 170.091 164.947 129.129 1.00 49.85 ? 347 LYS F CA  1 
ATOM 3056 C C   . LYS F 1 258 ? 171.122 163.929 129.604 1.00 49.85 ? 347 LYS F C   1 
ATOM 3057 O O   . LYS F 1 258 ? 171.121 163.549 130.764 1.00 49.85 ? 347 LYS F O   1 
ATOM 3058 C CB  . LYS F 1 258 ? 170.536 166.363 129.550 1.00 49.85 ? 347 LYS F CB  1 
ATOM 3059 C CG  . LYS F 1 258 ? 169.587 167.460 129.056 1.00 49.85 ? 347 LYS F CG  1 
ATOM 3060 C CD  . LYS F 1 258 ? 170.122 168.863 129.365 1.00 49.85 ? 347 LYS F CD  1 
ATOM 3061 C CE  . LYS F 1 258 ? 169.087 169.905 128.921 1.00 49.85 ? 347 LYS F CE  1 
ATOM 3062 N NZ  . LYS F 1 258 ? 169.613 171.289 128.987 1.00 49.85 ? 347 LYS F NZ  1 
ATOM 3063 N N   . ASP F 1 259 ? 172.078 163.597 128.744 1.00 48.93 ? 348 ASP F N   1 
ATOM 3064 C CA  . ASP F 1 259 ? 173.309 162.875 129.084 1.00 48.93 ? 348 ASP F CA  1 
ATOM 3065 C C   . ASP F 1 259 ? 173.082 161.492 129.727 1.00 48.93 ? 348 ASP F C   1 
ATOM 3066 O O   . ASP F 1 259 ? 173.046 161.352 130.948 1.00 48.93 ? 348 ASP F O   1 
ATOM 3067 C CB  . ASP F 1 259 ? 174.201 163.787 129.947 1.00 48.93 ? 348 ASP F CB  1 
ATOM 3068 C CG  . ASP F 1 259 ? 175.562 163.155 130.238 1.00 48.93 ? 348 ASP F CG  1 
ATOM 3069 O OD1 . ASP F 1 259 ? 175.982 162.249 129.490 1.00 48.93 ? 348 ASP F OD1 1 
ATOM 3070 O OD2 . ASP F 1 259 ? 176.254 163.577 131.186 1.00 48.93 ? 348 ASP F OD2 1 
ATOM 3071 N N   . ARG F 1 260 ? 172.975 160.443 128.906 1.00 47.08 ? 349 ARG F N   1 
ATOM 3072 C CA  . ARG F 1 260 ? 172.861 159.039 129.358 1.00 47.08 ? 349 ARG F CA  1 
ATOM 3073 C C   . ARG F 1 260 ? 171.646 158.807 130.259 1.00 47.08 ? 349 ARG F C   1 
ATOM 3074 O O   . ARG F 1 260 ? 171.760 158.378 131.400 1.00 47.08 ? 349 ARG F O   1 
ATOM 3075 C CB  . ARG F 1 260 ? 174.195 158.548 129.955 1.00 47.08 ? 349 ARG F CB  1 
ATOM 3076 C CG  . ARG F 1 260 ? 175.298 158.495 128.889 1.00 47.08 ? 349 ARG F CG  1 
ATOM 3077 C CD  . ARG F 1 260 ? 176.695 158.464 129.503 1.00 47.08 ? 349 ARG F CD  1 
ATOM 3078 N NE  . ARG F 1 260 ? 177.005 159.766 130.116 1.00 47.08 ? 349 ARG F NE  1 
ATOM 3079 C CZ  . ARG F 1 260 ? 177.773 160.006 131.155 1.00 47.08 ? 349 ARG F CZ  1 
ATOM 3080 N NH1 . ARG F 1 260 ? 178.590 159.112 131.629 1.00 47.08 ? 349 ARG F NH1 1 
ATOM 3081 N NH2 . ARG F 1 260 ? 177.733 161.167 131.727 1.00 47.08 ? 349 ARG F NH2 1 
ATOM 3082 N N   . VAL F 1 261 ? 170.462 159.093 129.730 1.00 44.97 ? 350 VAL F N   1 
ATOM 3083 C CA  . VAL F 1 261 ? 169.181 158.769 130.367 1.00 44.97 ? 350 VAL F CA  1 
ATOM 3084 C C   . VAL F 1 261 ? 168.579 157.550 129.683 1.00 44.97 ? 350 VAL F C   1 
ATOM 3085 O O   . VAL F 1 261 ? 168.452 157.530 128.462 1.00 44.97 ? 350 VAL F O   1 
ATOM 3086 C CB  . VAL F 1 261 ? 168.212 159.962 130.321 1.00 44.97 ? 350 VAL F CB  1 
ATOM 3087 C CG1 . VAL F 1 261 ? 166.839 159.616 130.909 1.00 44.97 ? 350 VAL F CG1 1 
ATOM 3088 C CG2 . VAL F 1 261 ? 168.778 161.144 131.108 1.00 44.97 ? 350 VAL F CG2 1 
ATOM 3089 N N   . GLN F 1 262 ? 168.173 156.548 130.456 1.00 42.16 ? 351 GLN F N   1 
ATOM 3090 C CA  . GLN F 1 262 ? 167.350 155.433 129.996 1.00 42.16 ? 351 GLN F CA  1 
ATOM 3091 C C   . GLN F 1 262 ? 165.987 155.504 130.700 1.00 42.16 ? 351 GLN F C   1 
ATOM 3092 O O   . GLN F 1 262 ? 165.915 155.461 131.923 1.00 42.16 ? 351 GLN F O   1 
ATOM 3093 C CB  . GLN F 1 262 ? 168.115 154.132 130.257 1.00 42.16 ? 351 GLN F CB  1 
ATOM 3094 C CG  . GLN F 1 262 ? 167.341 152.903 129.763 1.00 42.16 ? 351 GLN F CG  1 
ATOM 3095 C CD  . GLN F 1 262 ? 168.065 151.581 130.010 1.00 42.16 ? 351 GLN F CD  1 
ATOM 3096 O OE1 . GLN F 1 262 ? 167.452 150.561 130.288 1.00 42.16 ? 351 GLN F OE1 1 
ATOM 3097 N NE2 . GLN F 1 262 ? 169.377 151.527 129.948 1.00 42.16 ? 351 GLN F NE2 1 
ATOM 3098 N N   . SER F 1 263 ? 164.902 155.641 129.941 1.00 40.18 ? 352 SER F N   1 
ATOM 3099 C CA  . SER F 1 263 ? 163.566 155.937 130.472 1.00 40.18 ? 352 SER F CA  1 
ATOM 3100 C C   . SER F 1 263 ? 162.482 155.053 129.861 1.00 40.18 ? 352 SER F C   1 
ATOM 3101 O O   . SER F 1 263 ? 162.525 154.745 128.672 1.00 40.18 ? 352 SER F O   1 
ATOM 3102 C CB  . SER F 1 263 ? 163.250 157.416 130.270 1.00 40.18 ? 352 SER F CB  1 
ATOM 3103 O OG  . SER F 1 263 ? 162.011 157.729 130.864 1.00 40.18 ? 352 SER F OG  1 
ATOM 3104 N N   . LYS F 1 264 ? 161.505 154.645 130.671 1.00 38.04 ? 353 LYS F N   1 
ATOM 3105 C CA  . LYS F 1 264 ? 160.308 153.905 130.258 1.00 38.04 ? 353 LYS F CA  1 
ATOM 3106 C C   . LYS F 1 264 ? 159.079 154.516 130.930 1.00 38.04 ? 353 LYS F C   1 
ATOM 3107 O O   . LYS F 1 264 ? 159.014 154.527 132.154 1.00 38.04 ? 353 LYS F O   1 
ATOM 3108 C CB  . LYS F 1 264 ? 160.547 152.432 130.623 1.00 38.04 ? 353 LYS F CB  1 
ATOM 3109 C CG  . LYS F 1 264 ? 159.507 151.470 130.048 1.00 38.04 ? 353 LYS F CG  1 
ATOM 3110 C CD  . LYS F 1 264 ? 159.776 150.041 130.542 1.00 38.04 ? 353 LYS F CD  1 
ATOM 3111 C CE  . LYS F 1 264 ? 158.781 149.090 129.880 1.00 38.04 ? 353 LYS F CE  1 
ATOM 3112 N NZ  . LYS F 1 264 ? 158.805 147.715 130.443 1.00 38.04 ? 353 LYS F NZ  1 
ATOM 3113 N N   . ILE F 1 265 ? 158.117 155.031 130.165 1.00 38.55 ? 354 ILE F N   1 
ATOM 3114 C CA  . ILE F 1 265 ? 156.916 155.710 130.692 1.00 38.55 ? 354 ILE F CA  1 
ATOM 3115 C C   . ILE F 1 265 ? 155.650 155.061 130.123 1.00 38.55 ? 354 ILE F C   1 
ATOM 3116 O O   . ILE F 1 265 ? 155.488 155.009 128.908 1.00 38.55 ? 354 ILE F O   1 
ATOM 3117 C CB  . ILE F 1 265 ? 156.952 157.236 130.415 1.00 38.55 ? 354 ILE F CB  1 
ATOM 3118 C CG1 . ILE F 1 265 ? 158.233 157.890 130.977 1.00 38.55 ? 354 ILE F CG1 1 
ATOM 3119 C CG2 . ILE F 1 265 ? 155.710 157.914 131.016 1.00 38.55 ? 354 ILE F CG2 1 
ATOM 3120 C CD1 . ILE F 1 265 ? 158.367 159.387 130.689 1.00 38.55 ? 354 ILE F CD1 1 
ATOM 3121 N N   . GLY F 1 266 ? 154.745 154.588 130.981 1.00 37.46 ? 355 GLY F N   1 
ATOM 3122 C CA  . GLY F 1 266 ? 153.464 153.989 130.594 1.00 37.46 ? 355 GLY F CA  1 
ATOM 3123 C C   . GLY F 1 266 ? 153.597 152.668 129.829 1.00 37.46 ? 355 GLY F C   1 
ATOM 3124 O O   . GLY F 1 266 ? 153.552 152.673 128.604 1.00 37.46 ? 355 GLY F O   1 
ATOM 3125 N N   . SER F 1 267 ? 153.721 151.527 130.509 1.00 36.13 ? 356 SER F N   1 
ATOM 3126 C CA  . SER F 1 267 ? 153.854 150.207 129.860 1.00 36.13 ? 356 SER F CA  1 
ATOM 3127 C C   . SER F 1 267 ? 152.925 149.137 130.414 1.00 36.13 ? 356 SER F C   1 
ATOM 3128 O O   . SER F 1 267 ? 152.587 149.137 131.593 1.00 36.13 ? 356 SER F O   1 
ATOM 3129 C CB  . SER F 1 267 ? 155.288 149.690 129.932 1.00 36.13 ? 356 SER F CB  1 
ATOM 3130 O OG  . SER F 1 267 ? 155.675 149.292 131.236 1.00 36.13 ? 356 SER F OG  1 
ATOM 3131 N N   . LEU F 1 268 ? 152.584 148.170 129.564 1.00 34.62 ? 357 LEU F N   1 
ATOM 3132 C CA  . LEU F 1 268 ? 151.911 146.932 129.948 1.00 34.62 ? 357 LEU F CA  1 
ATOM 3133 C C   . LEU F 1 268 ? 152.582 145.771 129.201 1.00 34.62 ? 357 LEU F C   1 
ATOM 3134 O O   . LEU F 1 268 ? 152.110 145.347 128.149 1.00 34.62 ? 357 LEU F O   1 
ATOM 3135 C CB  . LEU F 1 268 ? 150.395 147.100 129.712 1.00 34.62 ? 357 LEU F CB  1 
ATOM 3136 C CG  . LEU F 1 268 ? 149.503 146.077 130.438 1.00 34.62 ? 357 LEU F CG  1 
ATOM 3137 C CD1 . LEU F 1 268 ? 148.074 146.610 130.524 1.00 34.62 ? 357 LEU F CD1 1 
ATOM 3138 C CD2 . LEU F 1 268 ? 149.443 144.709 129.764 1.00 34.62 ? 357 LEU F CD2 1 
ATOM 3139 N N   . ASP F 1 269 ? 153.742 145.323 129.684 1.00 35.46 ? 358 ASP F N   1 
ATOM 3140 C CA  . ASP F 1 269 ? 154.634 144.395 128.972 1.00 35.46 ? 358 ASP F CA  1 
ATOM 3141 C C   . ASP F 1 269 ? 154.651 142.979 129.555 1.00 35.46 ? 358 ASP F C   1 
ATOM 3142 O O   . ASP F 1 269 ? 154.829 142.794 130.753 1.00 35.46 ? 358 ASP F O   1 
ATOM 3143 C CB  . ASP F 1 269 ? 156.064 144.937 128.948 1.00 35.46 ? 358 ASP F CB  1 
ATOM 3144 C CG  . ASP F 1 269 ? 156.237 146.264 128.205 1.00 35.46 ? 358 ASP F CG  1 
ATOM 3145 O OD1 . ASP F 1 269 ? 155.342 146.707 127.455 1.00 35.46 ? 358 ASP F OD1 1 
ATOM 3146 O OD2 . ASP F 1 269 ? 157.348 146.825 128.316 1.00 35.46 ? 358 ASP F OD2 1 
ATOM 3147 N N   . ASN F 1 270 ? 154.529 141.964 128.701 1.00 32.98 ? 359 ASN F N   1 
ATOM 3148 C CA  . ASN F 1 270 ? 154.582 140.552 129.082 1.00 32.98 ? 359 ASN F CA  1 
ATOM 3149 C C   . ASN F 1 270 ? 155.811 139.864 128.474 1.00 32.98 ? 359 ASN F C   1 
ATOM 3150 O O   . ASN F 1 270 ? 156.045 139.984 127.275 1.00 32.98 ? 359 ASN F O   1 
ATOM 3151 C CB  . ASN F 1 270 ? 153.270 139.866 128.669 1.00 32.98 ? 359 ASN F CB  1 
ATOM 3152 C CG  . ASN F 1 270 ? 152.053 140.562 129.241 1.00 32.98 ? 359 ASN F CG  1 
ATOM 3153 O OD1 . ASN F 1 270 ? 151.852 140.619 130.440 1.00 32.98 ? 359 ASN F OD1 1 
ATOM 3154 N ND2 . ASN F 1 270 ? 151.206 141.121 128.417 1.00 32.98 ? 359 ASN F ND2 1 
ATOM 3155 N N   . ILE F 1 271 ? 156.587 139.127 129.270 1.00 31.86 ? 360 ILE F N   1 
ATOM 3156 C CA  . ILE F 1 271 ? 157.798 138.423 128.816 1.00 31.86 ? 360 ILE F CA  1 
ATOM 3157 C C   . ILE F 1 271 ? 157.747 136.962 129.257 1.00 31.86 ? 360 ILE F C   1 
ATOM 3158 O O   . ILE F 1 271 ? 157.529 136.676 130.429 1.00 31.86 ? 360 ILE F O   1 
ATOM 3159 C CB  . ILE F 1 271 ? 159.077 139.135 129.327 1.00 31.86 ? 360 ILE F CB  1 
ATOM 3160 C CG1 . ILE F 1 271 ? 159.147 140.601 128.843 1.00 31.86 ? 360 ILE F CG1 1 
ATOM 3161 C CG2 . ILE F 1 271 ? 160.339 138.377 128.886 1.00 31.86 ? 360 ILE F CG2 1 
ATOM 3162 C CD1 . ILE F 1 271 ? 160.280 141.428 129.451 1.00 31.86 ? 360 ILE F CD1 1 
ATOM 3163 N N   . THR F 1 272 ? 158.008 136.034 128.346 1.00 32.83 ? 361 THR F N   1 
ATOM 3164 C CA  . THR F 1 272 ? 158.319 134.636 128.664 1.00 32.83 ? 361 THR F CA  1 
ATOM 3165 C C   . THR F 1 272 ? 159.724 134.336 128.169 1.00 32.83 ? 361 THR F C   1 
ATOM 3166 O O   . THR F 1 272 ? 159.980 134.455 126.975 1.00 32.83 ? 361 THR F O   1 
ATOM 3167 C CB  . THR F 1 272 ? 157.313 133.676 128.022 1.00 32.83 ? 361 THR F CB  1 
ATOM 3168 O OG1 . THR F 1 272 ? 156.010 133.997 128.431 1.00 32.83 ? 361 THR F OG1 1 
ATOM 3169 C CG2 . THR F 1 272 ? 157.539 132.230 128.436 1.00 32.83 ? 361 THR F CG2 1 
ATOM 3170 N N   . HIS F 1 273 ? 160.638 133.958 129.056 1.00 34.46 ? 362 HIS F N   1 
ATOM 3171 C CA  . HIS F 1 273 ? 162.037 133.691 128.723 1.00 34.46 ? 362 HIS F CA  1 
ATOM 3172 C C   . HIS F 1 273 ? 162.471 132.320 129.247 1.00 34.46 ? 362 HIS F C   1 
ATOM 3173 O O   . HIS F 1 273 ? 162.460 132.074 130.448 1.00 34.46 ? 362 HIS F O   1 
ATOM 3174 C CB  . HIS F 1 273 ? 162.883 134.862 129.236 1.00 34.46 ? 362 HIS F CB  1 
ATOM 3175 C CG  . HIS F 1 273 ? 164.326 134.813 128.822 1.00 34.46 ? 362 HIS F CG  1 
ATOM 3176 N ND1 . HIS F 1 273 ? 164.820 134.278 127.634 1.00 34.46 ? 362 HIS F ND1 1 
ATOM 3177 C CD2 . HIS F 1 273 ? 165.351 135.398 129.497 1.00 34.46 ? 362 HIS F CD2 1 
ATOM 3178 C CE1 . HIS F 1 273 ? 166.138 134.526 127.637 1.00 34.46 ? 362 HIS F CE1 1 
ATOM 3179 N NE2 . HIS F 1 273 ? 166.482 135.193 128.746 1.00 34.46 ? 362 HIS F NE2 1 
ATOM 3180 N N   . VAL F 1 274 ? 162.820 131.402 128.348 1.00 36.17 ? 363 VAL F N   1 
ATOM 3181 C CA  . VAL F 1 274 ? 163.099 129.993 128.674 1.00 36.17 ? 363 VAL F CA  1 
ATOM 3182 C C   . VAL F 1 274 ? 164.363 129.525 127.937 1.00 36.17 ? 363 VAL F C   1 
ATOM 3183 O O   . VAL F 1 274 ? 164.275 128.758 126.980 1.00 36.17 ? 363 VAL F O   1 
ATOM 3184 C CB  . VAL F 1 274 ? 161.864 129.098 128.397 1.00 36.17 ? 363 VAL F CB  1 
ATOM 3185 C CG1 . VAL F 1 274 ? 162.052 127.667 128.908 1.00 36.17 ? 363 VAL F CG1 1 
ATOM 3186 C CG2 . VAL F 1 274 ? 160.574 129.620 129.044 1.00 36.17 ? 363 VAL F CG2 1 
ATOM 3187 N N   . PRO F 1 275 ? 165.558 130.020 128.303 1.00 38.35 ? 364 PRO F N   1 
ATOM 3188 C CA  . PRO F 1 275 ? 166.802 129.578 127.690 1.00 38.35 ? 364 PRO F CA  1 
ATOM 3189 C C   . PRO F 1 275 ? 167.205 128.187 128.191 1.00 38.35 ? 364 PRO F C   1 
ATOM 3190 O O   . PRO F 1 275 ? 167.087 127.879 129.376 1.00 38.35 ? 364 PRO F O   1 
ATOM 3191 C CB  . PRO F 1 275 ? 167.829 130.650 128.056 1.00 38.35 ? 364 PRO F CB  1 
ATOM 3192 C CG  . PRO F 1 275 ? 167.345 131.144 129.410 1.00 38.35 ? 364 PRO F CG  1 
ATOM 3193 C CD  . PRO F 1 275 ? 165.826 131.039 129.306 1.00 38.35 ? 364 PRO F CD  1 
ATOM 3194 N N   . GLY F 1 276 ? 167.758 127.355 127.312 1.00 42.41 ? 365 GLY F N   1 
ATOM 3195 C CA  . GLY F 1 276 ? 168.241 126.019 127.674 1.00 42.41 ? 365 GLY F CA  1 
ATOM 3196 C C   . GLY F 1 276 ? 169.462 126.032 128.600 1.00 42.41 ? 365 GLY F C   1 
ATOM 3197 O O   . GLY F 1 276 ? 169.661 125.097 129.374 1.00 42.41 ? 365 GLY F O   1 
ATOM 3198 N N   . GLY F 1 277 ? 170.256 127.104 128.563 1.00 44.65 ? 366 GLY F N   1 
ATOM 3199 C CA  . GLY F 1 277 ? 171.361 127.356 129.482 1.00 44.65 ? 366 GLY F CA  1 
ATOM 3200 C C   . GLY F 1 277 ? 171.113 128.586 130.342 1.00 44.65 ? 366 GLY F C   1 
ATOM 3201 O O   . GLY F 1 277 ? 170.756 128.472 131.510 1.00 44.65 ? 366 GLY F O   1 
ATOM 3202 N N   . GLY F 1 278 ? 171.278 129.778 129.772 1.00 47.72 ? 367 GLY F N   1 
ATOM 3203 C CA  . GLY F 1 278 ? 171.006 131.045 130.462 1.00 47.72 ? 367 GLY F CA  1 
ATOM 3204 C C   . GLY F 1 278 ? 172.052 131.440 131.505 1.00 47.72 ? 367 GLY F C   1 
ATOM 3205 O O   . GLY F 1 278 ? 171.786 132.285 132.354 1.00 47.72 ? 367 GLY F O   1 
ATOM 3206 N N   . ASN F 1 279 ? 173.223 130.808 131.481 1.00 50.20 ? 368 ASN F N   1 
ATOM 3207 C CA  . ASN F 1 279 ? 174.355 131.123 132.351 1.00 50.20 ? 368 ASN F CA  1 
ATOM 3208 C C   . ASN F 1 279 ? 175.055 132.417 131.922 1.00 50.20 ? 368 ASN F C   1 
ATOM 3209 O O   . ASN F 1 279 ? 175.105 132.730 130.732 1.00 50.20 ? 368 ASN F O   1 
ATOM 3210 C CB  . ASN F 1 279 ? 175.335 129.941 132.373 1.00 50.20 ? 368 ASN F CB  1 
ATOM 3211 C CG  . ASN F 1 279 ? 174.694 128.669 132.869 1.00 50.20 ? 368 ASN F CG  1 
ATOM 3212 O OD1 . ASN F 1 279 ? 174.071 128.637 133.914 1.00 50.20 ? 368 ASN F OD1 1 
ATOM 3213 N ND2 . ASN F 1 279 ? 174.799 127.586 132.151 1.00 50.20 ? 368 ASN F ND2 1 
ATOM 3214 N N   . LYS F 1 280 ? 175.610 133.160 132.885 1.00 51.65 ? 369 LYS F N   1 
ATOM 3215 C CA  . LYS F 1 280 ? 176.273 134.455 132.671 1.00 51.65 ? 369 LYS F CA  1 
ATOM 3216 C C   . LYS F 1 280 ? 177.632 134.505 133.357 1.00 51.65 ? 369 LYS F C   1 
ATOM 3217 O O   . LYS F 1 280 ? 177.773 134.079 134.501 1.00 51.65 ? 369 LYS F O   1 
ATOM 3218 C CB  . LYS F 1 280 ? 175.388 135.612 133.168 1.00 51.65 ? 369 LYS F CB  1 
ATOM 3219 C CG  . LYS F 1 280 ? 174.026 135.669 132.460 1.00 51.65 ? 369 LYS F CG  1 
ATOM 3220 C CD  . LYS F 1 280 ? 173.144 136.841 132.914 1.00 51.65 ? 369 LYS F CD  1 
ATOM 3221 C CE  . LYS F 1 280 ? 173.736 138.195 132.507 1.00 51.65 ? 369 LYS F CE  1 
ATOM 3222 N NZ  . LYS F 1 280 ? 172.770 139.299 132.729 1.00 51.65 ? 369 LYS F NZ  1 
ATOM 3223 N N   . LYS F 1 281 ? 178.614 135.093 132.682 1.00 54.62 ? 370 LYS F N   1 
ATOM 3224 C CA  . LYS F 1 281 ? 179.947 135.399 133.210 1.00 54.62 ? 370 LYS F CA  1 
ATOM 3225 C C   . LYS F 1 281 ? 180.304 136.830 132.823 1.00 54.62 ? 370 LYS F C   1 
ATOM 3226 O O   . LYS F 1 281 ? 180.207 137.190 131.654 1.00 54.62 ? 370 LYS F O   1 
ATOM 3227 C CB  . LYS F 1 281 ? 180.919 134.340 132.675 1.00 54.62 ? 370 LYS F CB  1 
ATOM 3228 C CG  . LYS F 1 281 ? 182.394 134.554 133.046 1.00 54.62 ? 370 LYS F CG  1 
ATOM 3229 C CD  . LYS F 1 281 ? 183.204 133.325 132.593 1.00 54.62 ? 370 LYS F CD  1 
ATOM 3230 C CE  . LYS F 1 281 ? 184.713 133.570 132.468 1.00 54.62 ? 370 LYS F CE  1 
ATOM 3231 N NZ  . LYS F 1 281 ? 185.383 133.754 133.776 1.00 54.62 ? 370 LYS F NZ  1 
ATOM 3232 N N   . ILE F 1 282 ? 180.693 137.649 133.794 1.00 55.60 ? 371 ILE F N   1 
ATOM 3233 C CA  . ILE F 1 282 ? 181.004 139.073 133.600 1.00 55.60 ? 371 ILE F CA  1 
ATOM 3234 C C   . ILE F 1 282 ? 182.379 139.365 134.191 1.00 55.60 ? 371 ILE F C   1 
ATOM 3235 O O   . ILE F 1 282 ? 182.655 139.026 135.336 1.00 55.60 ? 371 ILE F O   1 
ATOM 3236 C CB  . ILE F 1 282 ? 179.908 139.980 134.209 1.00 55.60 ? 371 ILE F CB  1 
ATOM 3237 C CG1 . ILE F 1 282 ? 178.551 139.780 133.502 1.00 55.60 ? 371 ILE F CG1 1 
ATOM 3238 C CG2 . ILE F 1 282 ? 180.319 141.461 134.147 1.00 55.60 ? 371 ILE F CG2 1 
ATOM 3239 C CD1 . ILE F 1 282 ? 177.370 140.431 134.223 1.00 55.60 ? 371 ILE F CD1 1 
ATOM 3240 N N   . GLU F 1 283 ? 183.221 140.037 133.417 1.00 57.98 ? 372 GLU F N   1 
ATOM 3241 C CA  . GLU F 1 283 ? 184.620 140.341 133.724 1.00 57.98 ? 372 GLU F CA  1 
ATOM 3242 C C   . GLU F 1 283 ? 184.894 141.833 133.521 1.00 57.98 ? 372 GLU F C   1 
ATOM 3243 O O   . GLU F 1 283 ? 184.284 142.480 132.672 1.00 57.98 ? 372 GLU F O   1 
ATOM 3244 C CB  . GLU F 1 283 ? 185.544 139.531 132.805 1.00 57.98 ? 372 GLU F CB  1 
ATOM 3245 C CG  . GLU F 1 283 ? 185.333 138.008 132.815 1.00 57.98 ? 372 GLU F CG  1 
ATOM 3246 C CD  . GLU F 1 283 ? 185.781 137.332 134.119 1.00 57.98 ? 372 GLU F CD  1 
ATOM 3247 O OE1 . GLU F 1 283 ? 186.821 137.749 134.680 1.00 57.98 ? 372 GLU F OE1 1 
ATOM 3248 O OE2 . GLU F 1 283 ? 185.145 136.325 134.509 1.00 57.98 ? 372 GLU F OE2 1 
ATOM 3249 N N   . THR F 1 284 ? 185.816 142.407 134.286 1.00 61.09 ? 373 THR F N   1 
ATOM 3250 C CA  . THR F 1 284 ? 186.245 143.810 134.152 1.00 61.09 ? 373 THR F CA  1 
ATOM 3251 C C   . THR F 1 284 ? 187.665 143.952 134.675 1.00 61.09 ? 373 THR F C   1 
ATOM 3252 O O   . THR F 1 284 ? 187.924 143.642 135.834 1.00 61.09 ? 373 THR F O   1 
ATOM 3253 C CB  . THR F 1 284 ? 185.272 144.741 134.898 1.00 61.09 ? 373 THR F CB  1 
ATOM 3254 O OG1 . THR F 1 284 ? 184.104 144.879 134.125 1.00 61.09 ? 373 THR F OG1 1 
ATOM 3255 C CG2 . THR F 1 284 ? 185.784 146.155 135.151 1.00 61.09 ? 373 THR F CG2 1 
ATOM 3256 N N   . HIS F 1 285 ? 188.577 144.431 133.831 1.00 63.04 ? 374 HIS F N   1 
ATOM 3257 C CA  . HIS F 1 285 ? 189.974 144.726 134.163 1.00 63.04 ? 374 HIS F CA  1 
ATOM 3258 C C   . HIS F 1 285 ? 190.240 146.211 133.970 1.00 63.04 ? 374 HIS F C   1 
ATOM 3259 O O   . HIS F 1 285 ? 189.971 146.738 132.890 1.00 63.04 ? 374 HIS F O   1 
ATOM 3260 C CB  . HIS F 1 285 ? 190.914 143.923 133.256 1.00 63.04 ? 374 HIS F CB  1 
ATOM 3261 C CG  . HIS F 1 285 ? 190.818 142.426 133.398 1.00 63.04 ? 374 HIS F CG  1 
ATOM 3262 N ND1 . HIS F 1 285 ? 191.257 141.685 134.491 1.00 63.04 ? 374 HIS F ND1 1 
ATOM 3263 C CD2 . HIS F 1 285 ? 190.313 141.573 132.467 1.00 63.04 ? 374 HIS F CD2 1 
ATOM 3264 C CE1 . HIS F 1 285 ? 191.025 140.400 134.187 1.00 63.04 ? 374 HIS F CE1 1 
ATOM 3265 N NE2 . HIS F 1 285 ? 190.454 140.306 132.980 1.00 63.04 ? 374 HIS F NE2 1 
ATOM 3266 N N   . LYS F 1 286 ? 190.776 146.894 134.982 1.00 66.96 ? 375 LYS F N   1 
ATOM 3267 C CA  . LYS F 1 286 ? 191.120 148.319 134.895 1.00 66.96 ? 375 LYS F CA  1 
ATOM 3268 C C   . LYS F 1 286 ? 192.465 148.640 135.545 1.00 66.96 ? 375 LYS F C   1 
ATOM 3269 O O   . LYS F 1 286 ? 192.768 148.153 136.633 1.00 66.96 ? 375 LYS F O   1 
ATOM 3270 C CB  . LYS F 1 286 ? 189.940 149.137 135.440 1.00 66.96 ? 375 LYS F CB  1 
ATOM 3271 C CG  . LYS F 1 286 ? 190.114 150.648 135.228 1.00 66.96 ? 375 LYS F CG  1 
ATOM 3272 C CD  . LYS F 1 286 ? 188.790 151.418 135.364 1.00 66.96 ? 375 LYS F CD  1 
ATOM 3273 C CE  . LYS F 1 286 ? 187.888 151.176 134.145 1.00 66.96 ? 375 LYS F CE  1 
ATOM 3274 N NZ  . LYS F 1 286 ? 186.581 151.864 134.265 1.00 66.96 ? 375 LYS F NZ  1 
ATOM 3275 N N   . LEU F 1 287 ? 193.258 149.456 134.856 1.00 70.56 ? 376 LEU F N   1 
ATOM 3276 C CA  . LEU F 1 287 ? 194.529 150.021 135.312 1.00 70.56 ? 376 LEU F CA  1 
ATOM 3277 C C   . LEU F 1 287 ? 194.548 151.525 135.013 1.00 70.56 ? 376 LEU F C   1 
ATOM 3278 O O   . LEU F 1 287 ? 194.289 151.923 133.879 1.00 70.56 ? 376 LEU F O   1 
ATOM 3279 C CB  . LEU F 1 287 ? 195.677 149.249 134.637 1.00 70.56 ? 376 LEU F CB  1 
ATOM 3280 C CG  . LEU F 1 287 ? 197.088 149.825 134.851 1.00 70.56 ? 376 LEU F CG  1 
ATOM 3281 C CD1 . LEU F 1 287 ? 197.475 149.913 136.322 1.00 70.56 ? 376 LEU F CD1 1 
ATOM 3282 C CD2 . LEU F 1 287 ? 198.112 148.917 134.172 1.00 70.56 ? 376 LEU F CD2 1 
ATOM 3283 N N   . THR F 1 288 ? 194.876 152.359 136.001 1.00 73.81 ? 377 THR F N   1 
ATOM 3284 C CA  . THR F 1 288 ? 194.781 153.830 135.904 1.00 73.81 ? 377 THR F CA  1 
ATOM 3285 C C   . THR F 1 288 ? 195.977 154.531 136.558 1.00 73.81 ? 377 THR F C   1 
ATOM 3286 O O   . THR F 1 288 ? 196.408 154.136 137.639 1.00 73.81 ? 377 THR F O   1 
ATOM 3287 C CB  . THR F 1 288 ? 193.465 154.306 136.551 1.00 73.81 ? 377 THR F CB  1 
ATOM 3288 O OG1 . THR F 1 288 ? 192.353 153.772 135.868 1.00 73.81 ? 377 THR F OG1 1 
ATOM 3289 C CG2 . THR F 1 288 ? 193.266 155.818 136.559 1.00 73.81 ? 377 THR F CG2 1 
ATOM 3290 N N   . PHE F 1 289 ? 196.456 155.621 135.955 1.00 77.42 ? 378 PHE F N   1 
ATOM 3291 C CA  . PHE F 1 289 ? 197.500 156.502 136.500 1.00 77.42 ? 378 PHE F CA  1 
ATOM 3292 C C   . PHE F 1 289 ? 196.975 157.920 136.767 1.00 77.42 ? 378 PHE F C   1 
ATOM 3293 O O   . PHE F 1 289 ? 196.227 158.491 135.965 1.00 77.42 ? 378 PHE F O   1 
ATOM 3294 C CB  . PHE F 1 289 ? 198.718 156.520 135.569 1.00 77.42 ? 378 PHE F CB  1 
ATOM 3295 C CG  . PHE F 1 289 ? 199.448 155.196 135.472 1.00 77.42 ? 378 PHE F CG  1 
ATOM 3296 C CD1 . PHE F 1 289 ? 199.031 154.224 134.545 1.00 77.42 ? 378 PHE F CD1 1 
ATOM 3297 C CD2 . PHE F 1 289 ? 200.536 154.921 136.324 1.00 77.42 ? 378 PHE F CD2 1 
ATOM 3298 C CE1 . PHE F 1 289 ? 199.697 152.987 134.468 1.00 77.42 ? 378 PHE F CE1 1 
ATOM 3299 C CE2 . PHE F 1 289 ? 201.204 153.687 136.246 1.00 77.42 ? 378 PHE F CE2 1 
ATOM 3300 C CZ  . PHE F 1 289 ? 200.784 152.720 135.316 1.00 77.42 ? 378 PHE F CZ  1 
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