data_9H46
# 
_entry.id   9H46 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9H46         pdb_00009h46 10.2210/pdb9h46/pdb 
WWPDB D_1292142460 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-12-04 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9H46 
_pdbx_database_status.recvd_initial_deposition_date   2024-10-17 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              mathew.martin@newcastle.ac.uk 
_pdbx_contact_author.name_first         Martin 
_pdbx_contact_author.name_last          Noble 
_pdbx_contact_author.name_mi            E.N. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-3595-9807 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Pintar, S.'    1 ?                   
'Martin, M.P.'  2 0000-0003-4810-3351 
'Noble, M.E.M.' 3 0000-0002-3595-9807 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;Covalent alkynylpyridopyrimidinones targeting cysteine 775 of the epidermal growth factor receptor overcome resistance to current therapies
;
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Stewart, H.L.' 1 ? 
primary 'Waring, M.J.'  2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Epidermal growth factor receptor'                                         37435.328 1  2.7.10.1 ? ? ? 
2 non-polymer syn '5-ethyl-2-[(2-methoxyphenyl)amino]-8-phenyl-pyrido[2,3-d]pyrimidin-7-one' 372.420   1  ?        ? ? ? 
3 water       nat water                                                                      18.015    31 ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHV
CRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKIT
DFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLP
QPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDAD
EYLIPQQG
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHV
CRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKIT
DFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLP
QPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDAD
EYLIPQQG
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '5-ethyl-2-[(2-methoxyphenyl)amino]-8-phenyl-pyrido[2,3-d]pyrimidin-7-one' A1ISA 
3 water                                                                      HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   GLU n 
1 4   ALA n 
1 5   PRO n 
1 6   ASN n 
1 7   GLN n 
1 8   ALA n 
1 9   LEU n 
1 10  LEU n 
1 11  ARG n 
1 12  ILE n 
1 13  LEU n 
1 14  LYS n 
1 15  GLU n 
1 16  THR n 
1 17  GLU n 
1 18  PHE n 
1 19  LYS n 
1 20  LYS n 
1 21  ILE n 
1 22  LYS n 
1 23  VAL n 
1 24  LEU n 
1 25  GLY n 
1 26  SER n 
1 27  GLY n 
1 28  ALA n 
1 29  PHE n 
1 30  GLY n 
1 31  THR n 
1 32  VAL n 
1 33  TYR n 
1 34  LYS n 
1 35  GLY n 
1 36  LEU n 
1 37  TRP n 
1 38  ILE n 
1 39  PRO n 
1 40  GLU n 
1 41  GLY n 
1 42  GLU n 
1 43  LYS n 
1 44  VAL n 
1 45  LYS n 
1 46  ILE n 
1 47  PRO n 
1 48  VAL n 
1 49  ALA n 
1 50  ILE n 
1 51  LYS n 
1 52  GLU n 
1 53  LEU n 
1 54  ARG n 
1 55  GLU n 
1 56  ALA n 
1 57  THR n 
1 58  SER n 
1 59  PRO n 
1 60  LYS n 
1 61  ALA n 
1 62  ASN n 
1 63  LYS n 
1 64  GLU n 
1 65  ILE n 
1 66  LEU n 
1 67  ASP n 
1 68  GLU n 
1 69  ALA n 
1 70  TYR n 
1 71  VAL n 
1 72  MET n 
1 73  ALA n 
1 74  SER n 
1 75  VAL n 
1 76  ASP n 
1 77  ASN n 
1 78  PRO n 
1 79  HIS n 
1 80  VAL n 
1 81  CYS n 
1 82  ARG n 
1 83  LEU n 
1 84  LEU n 
1 85  GLY n 
1 86  ILE n 
1 87  CYS n 
1 88  LEU n 
1 89  THR n 
1 90  SER n 
1 91  THR n 
1 92  VAL n 
1 93  GLN n 
1 94  LEU n 
1 95  ILE n 
1 96  THR n 
1 97  GLN n 
1 98  LEU n 
1 99  MET n 
1 100 PRO n 
1 101 PHE n 
1 102 GLY n 
1 103 CYS n 
1 104 LEU n 
1 105 LEU n 
1 106 ASP n 
1 107 TYR n 
1 108 VAL n 
1 109 ARG n 
1 110 GLU n 
1 111 HIS n 
1 112 LYS n 
1 113 ASP n 
1 114 ASN n 
1 115 ILE n 
1 116 GLY n 
1 117 SER n 
1 118 GLN n 
1 119 TYR n 
1 120 LEU n 
1 121 LEU n 
1 122 ASN n 
1 123 TRP n 
1 124 CYS n 
1 125 VAL n 
1 126 GLN n 
1 127 ILE n 
1 128 ALA n 
1 129 LYS n 
1 130 GLY n 
1 131 MET n 
1 132 ASN n 
1 133 TYR n 
1 134 LEU n 
1 135 GLU n 
1 136 ASP n 
1 137 ARG n 
1 138 ARG n 
1 139 LEU n 
1 140 VAL n 
1 141 HIS n 
1 142 ARG n 
1 143 ASP n 
1 144 LEU n 
1 145 ALA n 
1 146 ALA n 
1 147 ARG n 
1 148 ASN n 
1 149 VAL n 
1 150 LEU n 
1 151 VAL n 
1 152 LYS n 
1 153 THR n 
1 154 PRO n 
1 155 GLN n 
1 156 HIS n 
1 157 VAL n 
1 158 LYS n 
1 159 ILE n 
1 160 THR n 
1 161 ASP n 
1 162 PHE n 
1 163 GLY n 
1 164 LEU n 
1 165 ALA n 
1 166 LYS n 
1 167 LEU n 
1 168 LEU n 
1 169 GLY n 
1 170 ALA n 
1 171 GLU n 
1 172 GLU n 
1 173 LYS n 
1 174 GLU n 
1 175 TYR n 
1 176 HIS n 
1 177 ALA n 
1 178 GLU n 
1 179 GLY n 
1 180 GLY n 
1 181 LYS n 
1 182 VAL n 
1 183 PRO n 
1 184 ILE n 
1 185 LYS n 
1 186 TRP n 
1 187 MET n 
1 188 ALA n 
1 189 LEU n 
1 190 GLU n 
1 191 SER n 
1 192 ILE n 
1 193 LEU n 
1 194 HIS n 
1 195 ARG n 
1 196 ILE n 
1 197 TYR n 
1 198 THR n 
1 199 HIS n 
1 200 GLN n 
1 201 SER n 
1 202 ASP n 
1 203 VAL n 
1 204 TRP n 
1 205 SER n 
1 206 TYR n 
1 207 GLY n 
1 208 VAL n 
1 209 THR n 
1 210 VAL n 
1 211 TRP n 
1 212 GLU n 
1 213 LEU n 
1 214 MET n 
1 215 THR n 
1 216 PHE n 
1 217 GLY n 
1 218 SER n 
1 219 LYS n 
1 220 PRO n 
1 221 TYR n 
1 222 ASP n 
1 223 GLY n 
1 224 ILE n 
1 225 PRO n 
1 226 ALA n 
1 227 SER n 
1 228 GLU n 
1 229 ILE n 
1 230 SER n 
1 231 SER n 
1 232 ILE n 
1 233 LEU n 
1 234 GLU n 
1 235 LYS n 
1 236 GLY n 
1 237 GLU n 
1 238 ARG n 
1 239 LEU n 
1 240 PRO n 
1 241 GLN n 
1 242 PRO n 
1 243 PRO n 
1 244 ILE n 
1 245 CYS n 
1 246 THR n 
1 247 ILE n 
1 248 ASP n 
1 249 VAL n 
1 250 TYR n 
1 251 MET n 
1 252 ILE n 
1 253 MET n 
1 254 VAL n 
1 255 LYS n 
1 256 CYS n 
1 257 TRP n 
1 258 MET n 
1 259 ILE n 
1 260 ASP n 
1 261 ALA n 
1 262 ASP n 
1 263 SER n 
1 264 ARG n 
1 265 PRO n 
1 266 LYS n 
1 267 PHE n 
1 268 ARG n 
1 269 GLU n 
1 270 LEU n 
1 271 ILE n 
1 272 ILE n 
1 273 GLU n 
1 274 PHE n 
1 275 SER n 
1 276 LYS n 
1 277 MET n 
1 278 ALA n 
1 279 ARG n 
1 280 ASP n 
1 281 PRO n 
1 282 GLN n 
1 283 ARG n 
1 284 TYR n 
1 285 LEU n 
1 286 VAL n 
1 287 ILE n 
1 288 GLN n 
1 289 GLY n 
1 290 ASP n 
1 291 GLU n 
1 292 ARG n 
1 293 MET n 
1 294 HIS n 
1 295 LEU n 
1 296 PRO n 
1 297 SER n 
1 298 PRO n 
1 299 THR n 
1 300 ASP n 
1 301 SER n 
1 302 ASN n 
1 303 PHE n 
1 304 TYR n 
1 305 ARG n 
1 306 ALA n 
1 307 LEU n 
1 308 MET n 
1 309 ASP n 
1 310 GLU n 
1 311 GLU n 
1 312 ASP n 
1 313 MET n 
1 314 ASP n 
1 315 ASP n 
1 316 VAL n 
1 317 VAL n 
1 318 ASP n 
1 319 ALA n 
1 320 ASP n 
1 321 GLU n 
1 322 TYR n 
1 323 LEU n 
1 324 ILE n 
1 325 PRO n 
1 326 GLN n 
1 327 GLN n 
1 328 GLY n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   328 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'EGFR, ERBB, ERBB1, HER1' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1ISA non-polymer         . '5-ethyl-2-[(2-methoxyphenyl)amino]-8-phenyl-pyrido[2,3-d]pyrimidin-7-one' ? 'C22 H20 N4 O2'  372.420 
ALA   'L-peptide linking' y ALANINE                                                                    ? 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE                                                                   ? 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE                                                                 ? 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'                                                            ? 'C4 H7 N O4'     133.103 
CYS   'L-peptide linking' y CYSTEINE                                                                   ? 'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE                                                                  ? 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'                                                            ? 'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE                                                                    ? 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE                                                                  ? 'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER                                                                      ? 'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE                                                                 ? 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE                                                                    ? 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE                                                                     ? 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE                                                                 ? 'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE                                                              ? 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE                                                                    ? 'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE                                                                     ? 'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE                                                                  ? 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN                                                                 ? 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE                                                                   ? 'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE                                                                     ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   695  ?    ?   ?   A . n 
A 1 2   GLY 2   696  696  GLY GLY A . n 
A 1 3   GLU 3   697  697  GLU GLU A . n 
A 1 4   ALA 4   698  698  ALA ALA A . n 
A 1 5   PRO 5   699  699  PRO PRO A . n 
A 1 6   ASN 6   700  700  ASN ASN A . n 
A 1 7   GLN 7   701  701  GLN GLN A . n 
A 1 8   ALA 8   702  702  ALA ALA A . n 
A 1 9   LEU 9   703  703  LEU LEU A . n 
A 1 10  LEU 10  704  704  LEU LEU A . n 
A 1 11  ARG 11  705  705  ARG ARG A . n 
A 1 12  ILE 12  706  706  ILE ILE A . n 
A 1 13  LEU 13  707  707  LEU LEU A . n 
A 1 14  LYS 14  708  708  LYS LYS A . n 
A 1 15  GLU 15  709  709  GLU GLU A . n 
A 1 16  THR 16  710  710  THR THR A . n 
A 1 17  GLU 17  711  711  GLU GLU A . n 
A 1 18  PHE 18  712  712  PHE PHE A . n 
A 1 19  LYS 19  713  713  LYS LYS A . n 
A 1 20  LYS 20  714  714  LYS LYS A . n 
A 1 21  ILE 21  715  715  ILE ILE A . n 
A 1 22  LYS 22  716  716  LYS LYS A . n 
A 1 23  VAL 23  717  717  VAL VAL A . n 
A 1 24  LEU 24  718  718  LEU LEU A . n 
A 1 25  GLY 25  719  719  GLY GLY A . n 
A 1 26  SER 26  720  720  SER SER A . n 
A 1 27  GLY 27  721  721  GLY GLY A . n 
A 1 28  ALA 28  722  722  ALA ALA A . n 
A 1 29  PHE 29  723  723  PHE PHE A . n 
A 1 30  GLY 30  724  724  GLY GLY A . n 
A 1 31  THR 31  725  725  THR THR A . n 
A 1 32  VAL 32  726  726  VAL VAL A . n 
A 1 33  TYR 33  727  727  TYR TYR A . n 
A 1 34  LYS 34  728  728  LYS LYS A . n 
A 1 35  GLY 35  729  729  GLY GLY A . n 
A 1 36  LEU 36  730  730  LEU LEU A . n 
A 1 37  TRP 37  731  731  TRP TRP A . n 
A 1 38  ILE 38  732  732  ILE ILE A . n 
A 1 39  PRO 39  733  733  PRO PRO A . n 
A 1 40  GLU 40  734  734  GLU GLU A . n 
A 1 41  GLY 41  735  735  GLY GLY A . n 
A 1 42  GLU 42  736  736  GLU GLU A . n 
A 1 43  LYS 43  737  737  LYS LYS A . n 
A 1 44  VAL 44  738  738  VAL VAL A . n 
A 1 45  LYS 45  739  739  LYS LYS A . n 
A 1 46  ILE 46  740  740  ILE ILE A . n 
A 1 47  PRO 47  741  741  PRO PRO A . n 
A 1 48  VAL 48  742  742  VAL VAL A . n 
A 1 49  ALA 49  743  743  ALA ALA A . n 
A 1 50  ILE 50  744  744  ILE ILE A . n 
A 1 51  LYS 51  745  745  LYS LYS A . n 
A 1 52  GLU 52  746  746  GLU GLU A . n 
A 1 53  LEU 53  747  747  LEU LEU A . n 
A 1 54  ARG 54  748  748  ARG ARG A . n 
A 1 55  GLU 55  749  749  GLU GLU A . n 
A 1 56  ALA 56  750  750  ALA ALA A . n 
A 1 57  THR 57  751  751  THR THR A . n 
A 1 58  SER 58  752  752  SER SER A . n 
A 1 59  PRO 59  753  753  PRO PRO A . n 
A 1 60  LYS 60  754  754  LYS LYS A . n 
A 1 61  ALA 61  755  755  ALA ALA A . n 
A 1 62  ASN 62  756  756  ASN ASN A . n 
A 1 63  LYS 63  757  757  LYS LYS A . n 
A 1 64  GLU 64  758  758  GLU GLU A . n 
A 1 65  ILE 65  759  759  ILE ILE A . n 
A 1 66  LEU 66  760  760  LEU LEU A . n 
A 1 67  ASP 67  761  761  ASP ASP A . n 
A 1 68  GLU 68  762  762  GLU GLU A . n 
A 1 69  ALA 69  763  763  ALA ALA A . n 
A 1 70  TYR 70  764  764  TYR TYR A . n 
A 1 71  VAL 71  765  765  VAL VAL A . n 
A 1 72  MET 72  766  766  MET MET A . n 
A 1 73  ALA 73  767  767  ALA ALA A . n 
A 1 74  SER 74  768  768  SER SER A . n 
A 1 75  VAL 75  769  769  VAL VAL A . n 
A 1 76  ASP 76  770  770  ASP ASP A . n 
A 1 77  ASN 77  771  771  ASN ASN A . n 
A 1 78  PRO 78  772  772  PRO PRO A . n 
A 1 79  HIS 79  773  773  HIS HIS A . n 
A 1 80  VAL 80  774  774  VAL VAL A . n 
A 1 81  CYS 81  775  775  CYS CYS A . n 
A 1 82  ARG 82  776  776  ARG ARG A . n 
A 1 83  LEU 83  777  777  LEU LEU A . n 
A 1 84  LEU 84  778  778  LEU LEU A . n 
A 1 85  GLY 85  779  779  GLY GLY A . n 
A 1 86  ILE 86  780  780  ILE ILE A . n 
A 1 87  CYS 87  781  781  CYS CYS A . n 
A 1 88  LEU 88  782  782  LEU LEU A . n 
A 1 89  THR 89  783  783  THR THR A . n 
A 1 90  SER 90  784  784  SER SER A . n 
A 1 91  THR 91  785  785  THR THR A . n 
A 1 92  VAL 92  786  786  VAL VAL A . n 
A 1 93  GLN 93  787  787  GLN GLN A . n 
A 1 94  LEU 94  788  788  LEU LEU A . n 
A 1 95  ILE 95  789  789  ILE ILE A . n 
A 1 96  THR 96  790  790  THR THR A . n 
A 1 97  GLN 97  791  791  GLN GLN A . n 
A 1 98  LEU 98  792  792  LEU LEU A . n 
A 1 99  MET 99  793  793  MET MET A . n 
A 1 100 PRO 100 794  794  PRO PRO A . n 
A 1 101 PHE 101 795  795  PHE PHE A . n 
A 1 102 GLY 102 796  796  GLY GLY A . n 
A 1 103 CYS 103 797  797  CYS CYS A . n 
A 1 104 LEU 104 798  798  LEU LEU A . n 
A 1 105 LEU 105 799  799  LEU LEU A . n 
A 1 106 ASP 106 800  800  ASP ASP A . n 
A 1 107 TYR 107 801  801  TYR TYR A . n 
A 1 108 VAL 108 802  802  VAL VAL A . n 
A 1 109 ARG 109 803  803  ARG ARG A . n 
A 1 110 GLU 110 804  804  GLU GLU A . n 
A 1 111 HIS 111 805  805  HIS HIS A . n 
A 1 112 LYS 112 806  806  LYS LYS A . n 
A 1 113 ASP 113 807  807  ASP ASP A . n 
A 1 114 ASN 114 808  808  ASN ASN A . n 
A 1 115 ILE 115 809  809  ILE ILE A . n 
A 1 116 GLY 116 810  810  GLY GLY A . n 
A 1 117 SER 117 811  811  SER SER A . n 
A 1 118 GLN 118 812  812  GLN GLN A . n 
A 1 119 TYR 119 813  813  TYR TYR A . n 
A 1 120 LEU 120 814  814  LEU LEU A . n 
A 1 121 LEU 121 815  815  LEU LEU A . n 
A 1 122 ASN 122 816  816  ASN ASN A . n 
A 1 123 TRP 123 817  817  TRP TRP A . n 
A 1 124 CYS 124 818  818  CYS CYS A . n 
A 1 125 VAL 125 819  819  VAL VAL A . n 
A 1 126 GLN 126 820  820  GLN GLN A . n 
A 1 127 ILE 127 821  821  ILE ILE A . n 
A 1 128 ALA 128 822  822  ALA ALA A . n 
A 1 129 LYS 129 823  823  LYS LYS A . n 
A 1 130 GLY 130 824  824  GLY GLY A . n 
A 1 131 MET 131 825  825  MET MET A . n 
A 1 132 ASN 132 826  826  ASN ASN A . n 
A 1 133 TYR 133 827  827  TYR TYR A . n 
A 1 134 LEU 134 828  828  LEU LEU A . n 
A 1 135 GLU 135 829  829  GLU GLU A . n 
A 1 136 ASP 136 830  830  ASP ASP A . n 
A 1 137 ARG 137 831  831  ARG ARG A . n 
A 1 138 ARG 138 832  832  ARG ARG A . n 
A 1 139 LEU 139 833  833  LEU LEU A . n 
A 1 140 VAL 140 834  834  VAL VAL A . n 
A 1 141 HIS 141 835  835  HIS HIS A . n 
A 1 142 ARG 142 836  836  ARG ARG A . n 
A 1 143 ASP 143 837  837  ASP ASP A . n 
A 1 144 LEU 144 838  838  LEU LEU A . n 
A 1 145 ALA 145 839  839  ALA ALA A . n 
A 1 146 ALA 146 840  840  ALA ALA A . n 
A 1 147 ARG 147 841  841  ARG ARG A . n 
A 1 148 ASN 148 842  842  ASN ASN A . n 
A 1 149 VAL 149 843  843  VAL VAL A . n 
A 1 150 LEU 150 844  844  LEU LEU A . n 
A 1 151 VAL 151 845  845  VAL VAL A . n 
A 1 152 LYS 152 846  846  LYS LYS A . n 
A 1 153 THR 153 847  847  THR THR A . n 
A 1 154 PRO 154 848  848  PRO PRO A . n 
A 1 155 GLN 155 849  849  GLN GLN A . n 
A 1 156 HIS 156 850  850  HIS HIS A . n 
A 1 157 VAL 157 851  851  VAL VAL A . n 
A 1 158 LYS 158 852  852  LYS LYS A . n 
A 1 159 ILE 159 853  853  ILE ILE A . n 
A 1 160 THR 160 854  854  THR THR A . n 
A 1 161 ASP 161 855  855  ASP ASP A . n 
A 1 162 PHE 162 856  856  PHE PHE A . n 
A 1 163 GLY 163 857  857  GLY GLY A . n 
A 1 164 LEU 164 858  858  LEU LEU A . n 
A 1 165 ALA 165 859  859  ALA ALA A . n 
A 1 166 LYS 166 860  860  LYS LYS A . n 
A 1 167 LEU 167 861  861  LEU LEU A . n 
A 1 168 LEU 168 862  862  LEU LEU A . n 
A 1 169 GLY 169 863  863  GLY GLY A . n 
A 1 170 ALA 170 864  864  ALA ALA A . n 
A 1 171 GLU 171 865  ?    ?   ?   A . n 
A 1 172 GLU 172 866  ?    ?   ?   A . n 
A 1 173 LYS 173 867  ?    ?   ?   A . n 
A 1 174 GLU 174 868  ?    ?   ?   A . n 
A 1 175 TYR 175 869  ?    ?   ?   A . n 
A 1 176 HIS 176 870  ?    ?   ?   A . n 
A 1 177 ALA 177 871  ?    ?   ?   A . n 
A 1 178 GLU 178 872  ?    ?   ?   A . n 
A 1 179 GLY 179 873  ?    ?   ?   A . n 
A 1 180 GLY 180 874  ?    ?   ?   A . n 
A 1 181 LYS 181 875  ?    ?   ?   A . n 
A 1 182 VAL 182 876  876  VAL VAL A . n 
A 1 183 PRO 183 877  877  PRO PRO A . n 
A 1 184 ILE 184 878  878  ILE ILE A . n 
A 1 185 LYS 185 879  879  LYS LYS A . n 
A 1 186 TRP 186 880  880  TRP TRP A . n 
A 1 187 MET 187 881  881  MET MET A . n 
A 1 188 ALA 188 882  882  ALA ALA A . n 
A 1 189 LEU 189 883  883  LEU LEU A . n 
A 1 190 GLU 190 884  884  GLU GLU A . n 
A 1 191 SER 191 885  885  SER SER A . n 
A 1 192 ILE 192 886  886  ILE ILE A . n 
A 1 193 LEU 193 887  887  LEU LEU A . n 
A 1 194 HIS 194 888  888  HIS HIS A . n 
A 1 195 ARG 195 889  889  ARG ARG A . n 
A 1 196 ILE 196 890  890  ILE ILE A . n 
A 1 197 TYR 197 891  891  TYR TYR A . n 
A 1 198 THR 198 892  892  THR THR A . n 
A 1 199 HIS 199 893  893  HIS HIS A . n 
A 1 200 GLN 200 894  894  GLN GLN A . n 
A 1 201 SER 201 895  895  SER SER A . n 
A 1 202 ASP 202 896  896  ASP ASP A . n 
A 1 203 VAL 203 897  897  VAL VAL A . n 
A 1 204 TRP 204 898  898  TRP TRP A . n 
A 1 205 SER 205 899  899  SER SER A . n 
A 1 206 TYR 206 900  900  TYR TYR A . n 
A 1 207 GLY 207 901  901  GLY GLY A . n 
A 1 208 VAL 208 902  902  VAL VAL A . n 
A 1 209 THR 209 903  903  THR THR A . n 
A 1 210 VAL 210 904  904  VAL VAL A . n 
A 1 211 TRP 211 905  905  TRP TRP A . n 
A 1 212 GLU 212 906  906  GLU GLU A . n 
A 1 213 LEU 213 907  907  LEU LEU A . n 
A 1 214 MET 214 908  908  MET MET A . n 
A 1 215 THR 215 909  909  THR THR A . n 
A 1 216 PHE 216 910  910  PHE PHE A . n 
A 1 217 GLY 217 911  911  GLY GLY A . n 
A 1 218 SER 218 912  912  SER SER A . n 
A 1 219 LYS 219 913  913  LYS LYS A . n 
A 1 220 PRO 220 914  914  PRO PRO A . n 
A 1 221 TYR 221 915  915  TYR TYR A . n 
A 1 222 ASP 222 916  916  ASP ASP A . n 
A 1 223 GLY 223 917  917  GLY GLY A . n 
A 1 224 ILE 224 918  918  ILE ILE A . n 
A 1 225 PRO 225 919  919  PRO PRO A . n 
A 1 226 ALA 226 920  920  ALA ALA A . n 
A 1 227 SER 227 921  921  SER SER A . n 
A 1 228 GLU 228 922  922  GLU GLU A . n 
A 1 229 ILE 229 923  923  ILE ILE A . n 
A 1 230 SER 230 924  924  SER SER A . n 
A 1 231 SER 231 925  925  SER SER A . n 
A 1 232 ILE 232 926  926  ILE ILE A . n 
A 1 233 LEU 233 927  927  LEU LEU A . n 
A 1 234 GLU 234 928  928  GLU GLU A . n 
A 1 235 LYS 235 929  929  LYS LYS A . n 
A 1 236 GLY 236 930  930  GLY GLY A . n 
A 1 237 GLU 237 931  931  GLU GLU A . n 
A 1 238 ARG 238 932  932  ARG ARG A . n 
A 1 239 LEU 239 933  933  LEU LEU A . n 
A 1 240 PRO 240 934  934  PRO PRO A . n 
A 1 241 GLN 241 935  935  GLN GLN A . n 
A 1 242 PRO 242 936  936  PRO PRO A . n 
A 1 243 PRO 243 937  937  PRO PRO A . n 
A 1 244 ILE 244 938  938  ILE ILE A . n 
A 1 245 CYS 245 939  939  CYS CYS A . n 
A 1 246 THR 246 940  940  THR THR A . n 
A 1 247 ILE 247 941  941  ILE ILE A . n 
A 1 248 ASP 248 942  942  ASP ASP A . n 
A 1 249 VAL 249 943  943  VAL VAL A . n 
A 1 250 TYR 250 944  944  TYR TYR A . n 
A 1 251 MET 251 945  945  MET MET A . n 
A 1 252 ILE 252 946  946  ILE ILE A . n 
A 1 253 MET 253 947  947  MET MET A . n 
A 1 254 VAL 254 948  948  VAL VAL A . n 
A 1 255 LYS 255 949  949  LYS LYS A . n 
A 1 256 CYS 256 950  950  CYS CYS A . n 
A 1 257 TRP 257 951  951  TRP TRP A . n 
A 1 258 MET 258 952  952  MET MET A . n 
A 1 259 ILE 259 953  953  ILE ILE A . n 
A 1 260 ASP 260 954  954  ASP ASP A . n 
A 1 261 ALA 261 955  955  ALA ALA A . n 
A 1 262 ASP 262 956  956  ASP ASP A . n 
A 1 263 SER 263 957  957  SER SER A . n 
A 1 264 ARG 264 958  958  ARG ARG A . n 
A 1 265 PRO 265 959  959  PRO PRO A . n 
A 1 266 LYS 266 960  960  LYS LYS A . n 
A 1 267 PHE 267 961  961  PHE PHE A . n 
A 1 268 ARG 268 962  962  ARG ARG A . n 
A 1 269 GLU 269 963  963  GLU GLU A . n 
A 1 270 LEU 270 964  964  LEU LEU A . n 
A 1 271 ILE 271 965  965  ILE ILE A . n 
A 1 272 ILE 272 966  966  ILE ILE A . n 
A 1 273 GLU 273 967  967  GLU GLU A . n 
A 1 274 PHE 274 968  968  PHE PHE A . n 
A 1 275 SER 275 969  969  SER SER A . n 
A 1 276 LYS 276 970  970  LYS LYS A . n 
A 1 277 MET 277 971  971  MET MET A . n 
A 1 278 ALA 278 972  972  ALA ALA A . n 
A 1 279 ARG 279 973  973  ARG ARG A . n 
A 1 280 ASP 280 974  974  ASP ASP A . n 
A 1 281 PRO 281 975  975  PRO PRO A . n 
A 1 282 GLN 282 976  976  GLN GLN A . n 
A 1 283 ARG 283 977  977  ARG ARG A . n 
A 1 284 TYR 284 978  978  TYR TYR A . n 
A 1 285 LEU 285 979  979  LEU LEU A . n 
A 1 286 VAL 286 980  980  VAL VAL A . n 
A 1 287 ILE 287 981  981  ILE ILE A . n 
A 1 288 GLN 288 982  982  GLN GLN A . n 
A 1 289 GLY 289 983  983  GLY GLY A . n 
A 1 290 ASP 290 984  984  ASP ASP A . n 
A 1 291 GLU 291 985  985  GLU GLU A . n 
A 1 292 ARG 292 986  986  ARG ARG A . n 
A 1 293 MET 293 987  987  MET MET A . n 
A 1 294 HIS 294 988  988  HIS HIS A . n 
A 1 295 LEU 295 989  989  LEU LEU A . n 
A 1 296 PRO 296 990  990  PRO PRO A . n 
A 1 297 SER 297 991  ?    ?   ?   A . n 
A 1 298 PRO 298 992  ?    ?   ?   A . n 
A 1 299 THR 299 993  ?    ?   ?   A . n 
A 1 300 ASP 300 994  ?    ?   ?   A . n 
A 1 301 SER 301 995  ?    ?   ?   A . n 
A 1 302 ASN 302 996  ?    ?   ?   A . n 
A 1 303 PHE 303 997  ?    ?   ?   A . n 
A 1 304 TYR 304 998  ?    ?   ?   A . n 
A 1 305 ARG 305 999  999  ARG ARG A . n 
A 1 306 ALA 306 1000 1000 ALA ALA A . n 
A 1 307 LEU 307 1001 1001 LEU LEU A . n 
A 1 308 MET 308 1002 1002 MET MET A . n 
A 1 309 ASP 309 1003 1003 ASP ASP A . n 
A 1 310 GLU 310 1004 1004 GLU GLU A . n 
A 1 311 GLU 311 1005 1005 GLU GLU A . n 
A 1 312 ASP 312 1006 1006 ASP ASP A . n 
A 1 313 MET 313 1007 1007 MET MET A . n 
A 1 314 ASP 314 1008 1008 ASP ASP A . n 
A 1 315 ASP 315 1009 1009 ASP ASP A . n 
A 1 316 VAL 316 1010 1010 VAL VAL A . n 
A 1 317 VAL 317 1011 1011 VAL VAL A . n 
A 1 318 ASP 318 1012 1012 ASP ASP A . n 
A 1 319 ALA 319 1013 1013 ALA ALA A . n 
A 1 320 ASP 320 1014 1014 ASP ASP A . n 
A 1 321 GLU 321 1015 1015 GLU GLU A . n 
A 1 322 TYR 322 1016 1016 TYR TYR A . n 
A 1 323 LEU 323 1017 1017 LEU LEU A . n 
A 1 324 ILE 324 1018 1018 ILE ILE A . n 
A 1 325 PRO 325 1019 1019 PRO PRO A . n 
A 1 326 GLN 326 1020 ?    ?   ?   A . n 
A 1 327 GLN 327 1021 ?    ?   ?   A . n 
A 1 328 GLY 328 1022 ?    ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1ISA 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1ISA 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 A1ISA 1  1101 1    A1ISA DRG A . 
C 3 HOH   1  1201 1222 HOH   HOH A . 
C 3 HOH   2  1202 1203 HOH   HOH A . 
C 3 HOH   3  1203 1209 HOH   HOH A . 
C 3 HOH   4  1204 1202 HOH   HOH A . 
C 3 HOH   5  1205 1227 HOH   HOH A . 
C 3 HOH   6  1206 1215 HOH   HOH A . 
C 3 HOH   7  1207 1201 HOH   HOH A . 
C 3 HOH   8  1208 1220 HOH   HOH A . 
C 3 HOH   9  1209 1211 HOH   HOH A . 
C 3 HOH   10 1210 1217 HOH   HOH A . 
C 3 HOH   11 1211 1213 HOH   HOH A . 
C 3 HOH   12 1212 1221 HOH   HOH A . 
C 3 HOH   13 1213 1205 HOH   HOH A . 
C 3 HOH   14 1214 1208 HOH   HOH A . 
C 3 HOH   15 1215 1206 HOH   HOH A . 
C 3 HOH   16 1216 1207 HOH   HOH A . 
C 3 HOH   17 1217 1228 HOH   HOH A . 
C 3 HOH   18 1218 1226 HOH   HOH A . 
C 3 HOH   19 1219 1204 HOH   HOH A . 
C 3 HOH   20 1220 1210 HOH   HOH A . 
C 3 HOH   21 1221 1218 HOH   HOH A . 
C 3 HOH   22 1222 1223 HOH   HOH A . 
C 3 HOH   23 1223 1214 HOH   HOH A . 
C 3 HOH   24 1224 1229 HOH   HOH A . 
C 3 HOH   25 1225 1216 HOH   HOH A . 
C 3 HOH   26 1226 1230 HOH   HOH A . 
C 3 HOH   27 1227 1219 HOH   HOH A . 
C 3 HOH   28 1228 1212 HOH   HOH A . 
C 3 HOH   29 1229 1224 HOH   HOH A . 
C 3 HOH   30 1230 1225 HOH   HOH A . 
C 3 HOH   31 1231 1231 HOH   HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A PHE 723  ? CG  ? A PHE 29  CG  
2  1 Y 1 A PHE 723  ? CD1 ? A PHE 29  CD1 
3  1 Y 1 A PHE 723  ? CD2 ? A PHE 29  CD2 
4  1 Y 1 A PHE 723  ? CE1 ? A PHE 29  CE1 
5  1 Y 1 A PHE 723  ? CE2 ? A PHE 29  CE2 
6  1 Y 1 A PHE 723  ? CZ  ? A PHE 29  CZ  
7  1 Y 1 A GLU 749  ? CG  ? A GLU 55  CG  
8  1 Y 1 A GLU 749  ? CD  ? A GLU 55  CD  
9  1 Y 1 A GLU 749  ? OE1 ? A GLU 55  OE1 
10 1 Y 1 A GLU 749  ? OE2 ? A GLU 55  OE2 
11 1 Y 1 A THR 751  ? OG1 ? A THR 57  OG1 
12 1 Y 1 A THR 751  ? CG2 ? A THR 57  CG2 
13 1 Y 1 A LYS 754  ? CG  ? A LYS 60  CG  
14 1 Y 1 A LYS 754  ? CD  ? A LYS 60  CD  
15 1 Y 1 A LYS 754  ? CE  ? A LYS 60  CE  
16 1 Y 1 A LYS 754  ? NZ  ? A LYS 60  NZ  
17 1 Y 1 A LYS 757  ? CG  ? A LYS 63  CG  
18 1 Y 1 A LYS 757  ? CD  ? A LYS 63  CD  
19 1 Y 1 A LYS 757  ? CE  ? A LYS 63  CE  
20 1 Y 1 A LYS 757  ? NZ  ? A LYS 63  NZ  
21 1 Y 1 A GLU 758  ? CG  ? A GLU 64  CG  
22 1 Y 1 A GLU 758  ? CD  ? A GLU 64  CD  
23 1 Y 1 A GLU 758  ? OE1 ? A GLU 64  OE1 
24 1 Y 1 A GLU 758  ? OE2 ? A GLU 64  OE2 
25 1 Y 1 A LEU 858  ? CG  ? A LEU 164 CG  
26 1 Y 1 A LEU 858  ? CD1 ? A LEU 164 CD1 
27 1 Y 1 A LEU 858  ? CD2 ? A LEU 164 CD2 
28 1 Y 1 A LYS 860  ? CG  ? A LYS 166 CG  
29 1 Y 1 A LYS 860  ? CD  ? A LYS 166 CD  
30 1 Y 1 A LYS 860  ? CE  ? A LYS 166 CE  
31 1 Y 1 A LYS 860  ? NZ  ? A LYS 166 NZ  
32 1 Y 1 A LYS 929  ? CG  ? A LYS 235 CG  
33 1 Y 1 A LYS 929  ? CD  ? A LYS 235 CD  
34 1 Y 1 A LYS 929  ? CE  ? A LYS 235 CE  
35 1 Y 1 A LYS 929  ? NZ  ? A LYS 235 NZ  
36 1 Y 1 A ARG 958  ? NH1 ? A ARG 264 NH1 
37 1 Y 1 A ARG 958  ? NH2 ? A ARG 264 NH2 
38 1 Y 1 A GLU 985  ? CG  ? A GLU 291 CG  
39 1 Y 1 A GLU 985  ? CD  ? A GLU 291 CD  
40 1 Y 1 A GLU 985  ? OE1 ? A GLU 291 OE1 
41 1 Y 1 A GLU 985  ? OE2 ? A GLU 291 OE2 
42 1 Y 1 A ARG 986  ? CG  ? A ARG 292 CG  
43 1 Y 1 A ARG 986  ? CD  ? A ARG 292 CD  
44 1 Y 1 A ARG 986  ? NE  ? A ARG 292 NE  
45 1 Y 1 A ARG 986  ? CZ  ? A ARG 292 CZ  
46 1 Y 1 A ARG 986  ? NH1 ? A ARG 292 NH1 
47 1 Y 1 A ARG 986  ? NH2 ? A ARG 292 NH2 
48 1 Y 1 A HIS 988  ? CG  ? A HIS 294 CG  
49 1 Y 1 A HIS 988  ? ND1 ? A HIS 294 ND1 
50 1 Y 1 A HIS 988  ? CD2 ? A HIS 294 CD2 
51 1 Y 1 A HIS 988  ? CE1 ? A HIS 294 CE1 
52 1 Y 1 A HIS 988  ? NE2 ? A HIS 294 NE2 
53 1 Y 1 A ARG 999  ? CG  ? A ARG 305 CG  
54 1 Y 1 A ARG 999  ? CD  ? A ARG 305 CD  
55 1 Y 1 A ARG 999  ? NE  ? A ARG 305 NE  
56 1 Y 1 A ARG 999  ? CZ  ? A ARG 305 CZ  
57 1 Y 1 A ARG 999  ? NH1 ? A ARG 305 NH1 
58 1 Y 1 A ARG 999  ? NH2 ? A ARG 305 NH2 
59 1 Y 1 A LEU 1001 ? CG  ? A LEU 307 CG  
60 1 Y 1 A LEU 1001 ? CD1 ? A LEU 307 CD1 
61 1 Y 1 A LEU 1001 ? CD2 ? A LEU 307 CD2 
62 1 Y 1 A ASP 1003 ? CG  ? A ASP 309 CG  
63 1 Y 1 A ASP 1003 ? OD1 ? A ASP 309 OD1 
64 1 Y 1 A ASP 1003 ? OD2 ? A ASP 309 OD2 
65 1 Y 1 A GLU 1005 ? CG  ? A GLU 311 CG  
66 1 Y 1 A GLU 1005 ? CD  ? A GLU 311 CD  
67 1 Y 1 A GLU 1005 ? OE1 ? A GLU 311 OE1 
68 1 Y 1 A GLU 1005 ? OE2 ? A GLU 311 OE2 
69 1 Y 1 A ASP 1006 ? CG  ? A ASP 312 CG  
70 1 Y 1 A ASP 1006 ? OD1 ? A ASP 312 OD1 
71 1 Y 1 A ASP 1006 ? OD2 ? A ASP 312 OD2 
72 1 Y 1 A MET 1007 ? CG  ? A MET 313 CG  
73 1 Y 1 A MET 1007 ? SD  ? A MET 313 SD  
74 1 Y 1 A MET 1007 ? CE  ? A MET 313 CE  
75 1 Y 1 A VAL 1010 ? CG1 ? A VAL 316 CG1 
76 1 Y 1 A VAL 1010 ? CG2 ? A VAL 316 CG2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? '5.8.0430 (refmacat 0.4.82)' 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2    ? ? ? .                            2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .                            3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .                            4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9H46 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     144.696 
_cell.length_a_esd                 ? 
_cell.length_b                     144.696 
_cell.length_b_esd                 ? 
_cell.length_c                     144.696 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9H46 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                197 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'I 2 3' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9H46 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.37 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          63.52 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.6 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;25 mM HEPES pH 8, 150 mM NaCl, 10 % glycerol, 1 mM DTT         85mM Tris pH 7.6, 140 mM acetate, 23.5 % Polyethylene glycol 4,000, 18% glycerol
;
_exptl_crystal_grow.pdbx_pH_range   7.5-8.5 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     173 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2019-12-05 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.92 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.92 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9H46 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              3.16 
_reflns.d_resolution_low                               45.799 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     8781 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                1.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          15.0 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1.0 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.029 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    3.16 
_reflns_shell.d_res_low                                     3.38 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.7 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             1580 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.712 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.40 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            0.000 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            0.000 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            0.000 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               115.876 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.948 
_refine.correlation_coeff_Fo_to_Fc_free          0.940 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9H46 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.163 
_refine.ls_d_res_low                             45.799 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     8781 
_refine.ls_number_reflns_R_free                  432 
_refine.ls_number_reflns_R_work                  8349 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.954 
_refine.ls_percent_reflns_R_free                 4.920 
_refine.ls_R_factor_all                          0.214 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2564 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2125 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  0.444 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             21.866 
_refine.overall_SU_ML                            0.356 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       3.163 
_refine_hist.d_res_low                        45.799 
_refine_hist.number_atoms_solvent             31 
_refine_hist.number_atoms_total               2422 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2363 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         28 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.006  0.012   2444  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016   2323  ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.343  1.819   3318  ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.464  1.757   5366  ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 6.372  5.000   302   ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 22.843 6.389   18    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 24.615 10.000  418   ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.365 10.000  96    ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.054  0.200   377   ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.006  0.020   2820  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020   520   ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.239  0.200   610   ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.231  0.200   2429  ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.194  0.200   1210  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.092  0.200   1429  ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.262  0.200   63    ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.039  0.200   2     ? r_symmetry_xyhbond_nbd_other   ? ? 
'X-RAY DIFFRACTION' ? 0.258  0.200   15    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.210  0.200   63    ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.277  0.200   2     ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 9.007  11.563  1217  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 8.982  11.565  1217  ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 12.633 20.852  1516  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 12.632 20.855  1517  ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 9.293  11.797  1227  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 9.290  11.797  1228  ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 13.508 21.536  1802  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 13.504 21.538  1803  ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 18.769 138.899 10284 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 18.768 138.898 10285 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 3.163  3.245  642 . 37 605 100.0000 . 0.303 . . 0.302 . . . . . 0.303 . 20 . 0.926 0.921 0.314 
'X-RAY DIFFRACTION' 3.245  3.334  627 . 39 588 100.0000 . 0.303 . . 0.307 . . . . . 0.301 . 20 . 0.931 0.944 0.251 
'X-RAY DIFFRACTION' 3.334  3.430  605 . 31 574 100.0000 . 0.275 . . 0.275 . . . . . 0.261 . 20 . 0.946 0.959 0.279 
'X-RAY DIFFRACTION' 3.430  3.535  585 . 37 548 100.0000 . 0.263 . . 0.260 . . . . . 0.239 . 20 . 0.951 0.924 0.307 
'X-RAY DIFFRACTION' 3.535  3.650  572 . 26 546 100.0000 . 0.237 . . 0.233 . . . . . 0.210 . 20 . 0.964 0.940 0.306 
'X-RAY DIFFRACTION' 3.650  3.777  537 . 37 500 100.0000 . 0.223 . . 0.221 . . . . . 0.197 . 20 . 0.969 0.954 0.244 
'X-RAY DIFFRACTION' 3.777  3.919  554 . 21 533 100.0000 . 0.222 . . 0.221 . . . . . 0.197 . 20 . 0.968 0.956 0.252 
'X-RAY DIFFRACTION' 3.919  4.077  504 . 26 478 100.0000 . 0.195 . . 0.194 . . . . . 0.177 . 20 . 0.975 0.944 0.214 
'X-RAY DIFFRACTION' 4.077  4.257  492 . 19 473 100.0000 . 0.197 . . 0.194 . . . . . 0.176 . 20 . 0.975 0.940 0.300 
'X-RAY DIFFRACTION' 4.257  4.463  471 . 25 446 100.0000 . 0.184 . . 0.183 . . . . . 0.164 . 20 . 0.977 0.980 0.197 
'X-RAY DIFFRACTION' 4.463  4.702  464 . 14 450 100.0000 . 0.174 . . 0.173 . . . . . 0.163 . 20 . 0.979 0.974 0.181 
'X-RAY DIFFRACTION' 4.702  4.984  426 . 17 409 100.0000 . 0.194 . . 0.193 . . . . . 0.181 . 20 . 0.976 0.971 0.214 
'X-RAY DIFFRACTION' 4.984  5.324  397 . 23 374 100.0000 . 0.189 . . 0.186 . . . . . 0.172 . 20 . 0.977 0.947 0.262 
'X-RAY DIFFRACTION' 5.324  5.744  378 . 16 362 100.0000 . 0.247 . . 0.237 . . . . . 0.223 . 20 . 0.956 0.899 0.462 
'X-RAY DIFFRACTION' 5.744  6.282  350 . 17 333 100.0000 . 0.235 . . 0.233 . . . . . 0.215 . 20 . 0.963 0.923 0.277 
'X-RAY DIFFRACTION' 6.282  7.007  319 . 17 302 100.0000 . 0.241 . . 0.233 . . . . . 0.235 . 20 . 0.962 0.915 0.412 
'X-RAY DIFFRACTION' 7.007  8.060  289 . 10 279 100.0000 . 0.208 . . 0.209 . . . . . 0.223 . 20 . 0.972 0.979 0.195 
'X-RAY DIFFRACTION' 8.060  9.795  241 . 11 230 100.0000 . 0.166 . . 0.167 . . . . . 0.198 . 20 . 0.984 0.991 0.155 
'X-RAY DIFFRACTION' 9.795  13.546 199 . 7  192 100.0000 . 0.166 . . 0.164 . . . . . 0.191 . 20 . 0.985 0.981 0.242 
'X-RAY DIFFRACTION' 13.546 45.799 129 . 2  127 100.0000 . 0.334 . . 0.333 . . . . . 0.401 . 20 . 0.924 1.000 0.355 
# 
_struct.entry_id                     9H46 
_struct.title                        'EGFR wild type in complex with 25328' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9H46 
_struct_keywords.text            'KINASE, EGFR, INHIBITOR, TRANSFERASE' 
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    EGFR_HUMAN 
_struct_ref.pdbx_db_accession          P00533 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;GEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVC
RLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITD
FGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQ
PPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADE
YLIPQQG
;
_struct_ref.pdbx_align_begin           696 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9H46 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 2 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 328 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P00533 
_struct_ref_seq.db_align_beg                  696 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1022 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       696 
_struct_ref_seq.pdbx_auth_seq_align_end       1022 
# 
_struct_ref_seq_dif.align_id                     1 
_struct_ref_seq_dif.pdbx_pdb_id_code             9H46 
_struct_ref_seq_dif.mon_id                       MET 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      1 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   P00533 
_struct_ref_seq_dif.db_mon_id                    ? 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          ? 
_struct_ref_seq_dif.details                      'initiating methionine' 
_struct_ref_seq_dif.pdbx_auth_seq_num            695 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 720   ? 
1 MORE         -1    ? 
1 'SSA (A^2)'  14890 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                monomer 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LYS A 14  ? THR A 16  ? LYS A 708  THR A 710  5 ? 3  
HELX_P HELX_P2  AA2 SER A 58  ? SER A 74  ? SER A 752  SER A 768  1 ? 17 
HELX_P HELX_P3  AA3 CYS A 103 ? HIS A 111 ? CYS A 797  HIS A 805  1 ? 9  
HELX_P HELX_P4  AA4 LYS A 112 ? ILE A 115 ? LYS A 806  ILE A 809  5 ? 4  
HELX_P HELX_P5  AA5 GLY A 116 ? ARG A 138 ? GLY A 810  ARG A 832  1 ? 23 
HELX_P HELX_P6  AA6 ALA A 145 ? ARG A 147 ? ALA A 839  ARG A 841  5 ? 3  
HELX_P HELX_P7  AA7 ALA A 188 ? ARG A 195 ? ALA A 882  ARG A 889  1 ? 8  
HELX_P HELX_P8  AA8 THR A 198 ? THR A 215 ? THR A 892  THR A 909  1 ? 18 
HELX_P HELX_P9  AA9 PRO A 225 ? GLY A 236 ? PRO A 919  GLY A 930  1 ? 12 
HELX_P HELX_P10 AB1 THR A 246 ? TRP A 257 ? THR A 940  TRP A 951  1 ? 12 
HELX_P HELX_P11 AB2 LYS A 266 ? ASP A 280 ? LYS A 960  ASP A 974  1 ? 15 
HELX_P HELX_P12 AB3 ASP A 280 ? LEU A 285 ? ASP A 974  LEU A 979  1 ? 6  
HELX_P HELX_P13 AB4 ASP A 318 ? TYR A 322 ? ASP A 1012 TYR A 1016 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            covale1 
_struct_conn.conn_type_id                  covale 
_struct_conn.pdbx_leaving_atom_flag        none 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            81 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           B 
_struct_conn.ptnr2_label_comp_id           A1ISA 
_struct_conn.ptnr2_label_seq_id            . 
_struct_conn.ptnr2_label_atom_id           C1 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             775 
_struct_conn.ptnr2_auth_asym_id            A 
_struct_conn.ptnr2_auth_comp_id            A1ISA 
_struct_conn.ptnr2_auth_seq_id             1101 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               1.767 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      A1ISA 
_pdbx_modification_feature.label_asym_id                      B 
_pdbx_modification_feature.label_seq_id                       . 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      81 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       A1ISA 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        1101 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       775 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               C1 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                CYS 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        A1ISA 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Covalent chemical modification' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 18  ? GLY A 25  ? PHE A 712 GLY A 719 
AA1 2 GLY A 30  ? TRP A 37  ? GLY A 724 TRP A 731 
AA1 3 ILE A 46  ? LEU A 53  ? ILE A 740 LEU A 747 
AA1 4 VAL A 92  ? GLN A 97  ? VAL A 786 GLN A 791 
AA1 5 LEU A 83  ? LEU A 88  ? LEU A 777 LEU A 782 
AA2 1 LEU A 139 ? VAL A 140 ? LEU A 833 VAL A 834 
AA2 2 LYS A 166 ? LEU A 167 ? LYS A 860 LEU A 861 
AA3 1 VAL A 149 ? THR A 153 ? VAL A 843 THR A 847 
AA3 2 HIS A 156 ? ILE A 159 ? HIS A 850 ILE A 853 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LYS A 19  ? N LYS A 713 O LEU A 36  ? O LEU A 730 
AA1 2 3 N TYR A 33  ? N TYR A 727 O ILE A 50  ? O ILE A 744 
AA1 3 4 N ALA A 49  ? N ALA A 743 O THR A 96  ? O THR A 790 
AA1 4 5 O GLN A 93  ? O GLN A 787 N CYS A 87  ? N CYS A 781 
AA2 1 2 N VAL A 140 ? N VAL A 834 O LYS A 166 ? O LYS A 860 
AA3 1 2 N LEU A 150 ? N LEU A 844 O LYS A 158 ? O LYS A 852 
# 
_pdbx_entry_details.entry_id                   9H46 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 HB3 A LYS 860 ? ? O   A HOH 1227 ? ? 1.55 
2 1 H   A TYR 727 ? ? O   A ILE 744  ? ? 1.57 
3 1 O   A SER 925 ? ? H   A LYS 929  ? ? 1.59 
4 1 O   A TRP 905 ? ? HG1 A THR 909  ? ? 1.59 
5 1 O   A ARG 831 ? ? O   A HOH 1201 ? ? 2.06 
6 1 O   A LYS 806 ? ? O   A HOH 1202 ? ? 2.09 
7 1 O   A ASN 771 ? ? O   A HOH 1203 ? ? 2.18 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ALA A 722  ? ? 64.63   -146.06 
2  1 GLU A 734  ? ? 51.29   -125.92 
3  1 ALA A 750  ? ? 56.86   -152.36 
4  1 THR A 751  ? ? -106.12 66.92   
5  1 ARG A 832  ? ? 87.68   5.23    
6  1 ARG A 836  ? ? 65.43   -1.15   
7  1 ASP A 837  ? ? -158.66 63.69   
8  1 ALA A 1000 ? ? 82.59   -64.13  
9  1 LEU A 1001 ? ? -52.73  108.63  
10 1 ASP A 1003 ? ? 62.14   -81.88  
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 695  ? A MET 1   
2  1 Y 1 A GLU 865  ? A GLU 171 
3  1 Y 1 A GLU 866  ? A GLU 172 
4  1 Y 1 A LYS 867  ? A LYS 173 
5  1 Y 1 A GLU 868  ? A GLU 174 
6  1 Y 1 A TYR 869  ? A TYR 175 
7  1 Y 1 A HIS 870  ? A HIS 176 
8  1 Y 1 A ALA 871  ? A ALA 177 
9  1 Y 1 A GLU 872  ? A GLU 178 
10 1 Y 1 A GLY 873  ? A GLY 179 
11 1 Y 1 A GLY 874  ? A GLY 180 
12 1 Y 1 A LYS 875  ? A LYS 181 
13 1 Y 1 A SER 991  ? A SER 297 
14 1 Y 1 A PRO 992  ? A PRO 298 
15 1 Y 1 A THR 993  ? A THR 299 
16 1 Y 1 A ASP 994  ? A ASP 300 
17 1 Y 1 A SER 995  ? A SER 301 
18 1 Y 1 A ASN 996  ? A ASN 302 
19 1 Y 1 A PHE 997  ? A PHE 303 
20 1 Y 1 A TYR 998  ? A TYR 304 
21 1 Y 1 A GLN 1020 ? A GLN 326 
22 1 Y 1 A GLN 1021 ? A GLN 327 
23 1 Y 1 A GLY 1022 ? A GLY 328 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1ISA C4   C N N 1   
A1ISA C14  C Y N 2   
A1ISA C5   C N N 3   
A1ISA C6   C Y N 4   
A1ISA C11  C Y N 5   
A1ISA C7   C Y N 6   
A1ISA C8   C Y N 7   
A1ISA C9   C Y N 8   
A1ISA C10  C Y N 9   
A1ISA C12  C Y N 10  
A1ISA C13  C Y N 11  
A1ISA N1   N N N 12  
A1ISA N2   N Y N 13  
A1ISA C3   C N N 14  
A1ISA N3   N N N 15  
A1ISA C1   C N N 16  
A1ISA C2   C N N 17  
A1ISA O1   O N N 18  
A1ISA C15  C Y N 19  
A1ISA C16  C Y N 20  
A1ISA C17  C Y N 21  
A1ISA C18  C Y N 22  
A1ISA C19  C Y N 23  
A1ISA O2   O N N 24  
A1ISA C20  C N N 25  
A1ISA N4   N Y N 26  
A1ISA C21  C Y N 27  
A1ISA C22  C Y N 28  
A1ISA H4   H N N 29  
A1ISA H9   H N N 30  
A1ISA H5   H N N 31  
A1ISA H6   H N N 32  
A1ISA H7   H N N 33  
A1ISA H8   H N N 34  
A1ISA H10  H N N 35  
A1ISA H1   H N N 36  
A1ISA H2   H N N 37  
A1ISA H3   H N N 38  
A1ISA H11  H N N 39  
A1ISA H12  H N N 40  
A1ISA H13  H N N 41  
A1ISA H14  H N N 42  
A1ISA H16  H N N 43  
A1ISA H17  H N N 44  
A1ISA H15  H N N 45  
A1ISA H18  H N N 46  
A1ISA H19  H N N 47  
A1ISA H20  H N N 48  
ALA   N    N N N 49  
ALA   CA   C N S 50  
ALA   C    C N N 51  
ALA   O    O N N 52  
ALA   CB   C N N 53  
ALA   OXT  O N N 54  
ALA   H    H N N 55  
ALA   H2   H N N 56  
ALA   HA   H N N 57  
ALA   HB1  H N N 58  
ALA   HB2  H N N 59  
ALA   HB3  H N N 60  
ALA   HXT  H N N 61  
ARG   N    N N N 62  
ARG   CA   C N S 63  
ARG   C    C N N 64  
ARG   O    O N N 65  
ARG   CB   C N N 66  
ARG   CG   C N N 67  
ARG   CD   C N N 68  
ARG   NE   N N N 69  
ARG   CZ   C N N 70  
ARG   NH1  N N N 71  
ARG   NH2  N N N 72  
ARG   OXT  O N N 73  
ARG   H    H N N 74  
ARG   H2   H N N 75  
ARG   HA   H N N 76  
ARG   HB2  H N N 77  
ARG   HB3  H N N 78  
ARG   HG2  H N N 79  
ARG   HG3  H N N 80  
ARG   HD2  H N N 81  
ARG   HD3  H N N 82  
ARG   HE   H N N 83  
ARG   HH11 H N N 84  
ARG   HH12 H N N 85  
ARG   HH21 H N N 86  
ARG   HH22 H N N 87  
ARG   HXT  H N N 88  
ASN   N    N N N 89  
ASN   CA   C N S 90  
ASN   C    C N N 91  
ASN   O    O N N 92  
ASN   CB   C N N 93  
ASN   CG   C N N 94  
ASN   OD1  O N N 95  
ASN   ND2  N N N 96  
ASN   OXT  O N N 97  
ASN   H    H N N 98  
ASN   H2   H N N 99  
ASN   HA   H N N 100 
ASN   HB2  H N N 101 
ASN   HB3  H N N 102 
ASN   HD21 H N N 103 
ASN   HD22 H N N 104 
ASN   HXT  H N N 105 
ASP   N    N N N 106 
ASP   CA   C N S 107 
ASP   C    C N N 108 
ASP   O    O N N 109 
ASP   CB   C N N 110 
ASP   CG   C N N 111 
ASP   OD1  O N N 112 
ASP   OD2  O N N 113 
ASP   OXT  O N N 114 
ASP   H    H N N 115 
ASP   H2   H N N 116 
ASP   HA   H N N 117 
ASP   HB2  H N N 118 
ASP   HB3  H N N 119 
ASP   HD2  H N N 120 
ASP   HXT  H N N 121 
CYS   N    N N N 122 
CYS   CA   C N R 123 
CYS   C    C N N 124 
CYS   O    O N N 125 
CYS   CB   C N N 126 
CYS   SG   S N N 127 
CYS   OXT  O N N 128 
CYS   H    H N N 129 
CYS   H2   H N N 130 
CYS   HA   H N N 131 
CYS   HB2  H N N 132 
CYS   HB3  H N N 133 
CYS   HG   H N N 134 
CYS   HXT  H N N 135 
GLN   N    N N N 136 
GLN   CA   C N S 137 
GLN   C    C N N 138 
GLN   O    O N N 139 
GLN   CB   C N N 140 
GLN   CG   C N N 141 
GLN   CD   C N N 142 
GLN   OE1  O N N 143 
GLN   NE2  N N N 144 
GLN   OXT  O N N 145 
GLN   H    H N N 146 
GLN   H2   H N N 147 
GLN   HA   H N N 148 
GLN   HB2  H N N 149 
GLN   HB3  H N N 150 
GLN   HG2  H N N 151 
GLN   HG3  H N N 152 
GLN   HE21 H N N 153 
GLN   HE22 H N N 154 
GLN   HXT  H N N 155 
GLU   N    N N N 156 
GLU   CA   C N S 157 
GLU   C    C N N 158 
GLU   O    O N N 159 
GLU   CB   C N N 160 
GLU   CG   C N N 161 
GLU   CD   C N N 162 
GLU   OE1  O N N 163 
GLU   OE2  O N N 164 
GLU   OXT  O N N 165 
GLU   H    H N N 166 
GLU   H2   H N N 167 
GLU   HA   H N N 168 
GLU   HB2  H N N 169 
GLU   HB3  H N N 170 
GLU   HG2  H N N 171 
GLU   HG3  H N N 172 
GLU   HE2  H N N 173 
GLU   HXT  H N N 174 
GLY   N    N N N 175 
GLY   CA   C N N 176 
GLY   C    C N N 177 
GLY   O    O N N 178 
GLY   OXT  O N N 179 
GLY   H    H N N 180 
GLY   H2   H N N 181 
GLY   HA2  H N N 182 
GLY   HA3  H N N 183 
GLY   HXT  H N N 184 
HIS   N    N N N 185 
HIS   CA   C N S 186 
HIS   C    C N N 187 
HIS   O    O N N 188 
HIS   CB   C N N 189 
HIS   CG   C Y N 190 
HIS   ND1  N Y N 191 
HIS   CD2  C Y N 192 
HIS   CE1  C Y N 193 
HIS   NE2  N Y N 194 
HIS   OXT  O N N 195 
HIS   H    H N N 196 
HIS   H2   H N N 197 
HIS   HA   H N N 198 
HIS   HB2  H N N 199 
HIS   HB3  H N N 200 
HIS   HD1  H N N 201 
HIS   HD2  H N N 202 
HIS   HE1  H N N 203 
HIS   HE2  H N N 204 
HIS   HXT  H N N 205 
HOH   O    O N N 206 
HOH   H1   H N N 207 
HOH   H2   H N N 208 
ILE   N    N N N 209 
ILE   CA   C N S 210 
ILE   C    C N N 211 
ILE   O    O N N 212 
ILE   CB   C N S 213 
ILE   CG1  C N N 214 
ILE   CG2  C N N 215 
ILE   CD1  C N N 216 
ILE   OXT  O N N 217 
ILE   H    H N N 218 
ILE   H2   H N N 219 
ILE   HA   H N N 220 
ILE   HB   H N N 221 
ILE   HG12 H N N 222 
ILE   HG13 H N N 223 
ILE   HG21 H N N 224 
ILE   HG22 H N N 225 
ILE   HG23 H N N 226 
ILE   HD11 H N N 227 
ILE   HD12 H N N 228 
ILE   HD13 H N N 229 
ILE   HXT  H N N 230 
LEU   N    N N N 231 
LEU   CA   C N S 232 
LEU   C    C N N 233 
LEU   O    O N N 234 
LEU   CB   C N N 235 
LEU   CG   C N N 236 
LEU   CD1  C N N 237 
LEU   CD2  C N N 238 
LEU   OXT  O N N 239 
LEU   H    H N N 240 
LEU   H2   H N N 241 
LEU   HA   H N N 242 
LEU   HB2  H N N 243 
LEU   HB3  H N N 244 
LEU   HG   H N N 245 
LEU   HD11 H N N 246 
LEU   HD12 H N N 247 
LEU   HD13 H N N 248 
LEU   HD21 H N N 249 
LEU   HD22 H N N 250 
LEU   HD23 H N N 251 
LEU   HXT  H N N 252 
LYS   N    N N N 253 
LYS   CA   C N S 254 
LYS   C    C N N 255 
LYS   O    O N N 256 
LYS   CB   C N N 257 
LYS   CG   C N N 258 
LYS   CD   C N N 259 
LYS   CE   C N N 260 
LYS   NZ   N N N 261 
LYS   OXT  O N N 262 
LYS   H    H N N 263 
LYS   H2   H N N 264 
LYS   HA   H N N 265 
LYS   HB2  H N N 266 
LYS   HB3  H N N 267 
LYS   HG2  H N N 268 
LYS   HG3  H N N 269 
LYS   HD2  H N N 270 
LYS   HD3  H N N 271 
LYS   HE2  H N N 272 
LYS   HE3  H N N 273 
LYS   HZ1  H N N 274 
LYS   HZ2  H N N 275 
LYS   HZ3  H N N 276 
LYS   HXT  H N N 277 
MET   N    N N N 278 
MET   CA   C N S 279 
MET   C    C N N 280 
MET   O    O N N 281 
MET   CB   C N N 282 
MET   CG   C N N 283 
MET   SD   S N N 284 
MET   CE   C N N 285 
MET   OXT  O N N 286 
MET   H    H N N 287 
MET   H2   H N N 288 
MET   HA   H N N 289 
MET   HB2  H N N 290 
MET   HB3  H N N 291 
MET   HG2  H N N 292 
MET   HG3  H N N 293 
MET   HE1  H N N 294 
MET   HE2  H N N 295 
MET   HE3  H N N 296 
MET   HXT  H N N 297 
PHE   N    N N N 298 
PHE   CA   C N S 299 
PHE   C    C N N 300 
PHE   O    O N N 301 
PHE   CB   C N N 302 
PHE   CG   C Y N 303 
PHE   CD1  C Y N 304 
PHE   CD2  C Y N 305 
PHE   CE1  C Y N 306 
PHE   CE2  C Y N 307 
PHE   CZ   C Y N 308 
PHE   OXT  O N N 309 
PHE   H    H N N 310 
PHE   H2   H N N 311 
PHE   HA   H N N 312 
PHE   HB2  H N N 313 
PHE   HB3  H N N 314 
PHE   HD1  H N N 315 
PHE   HD2  H N N 316 
PHE   HE1  H N N 317 
PHE   HE2  H N N 318 
PHE   HZ   H N N 319 
PHE   HXT  H N N 320 
PRO   N    N N N 321 
PRO   CA   C N S 322 
PRO   C    C N N 323 
PRO   O    O N N 324 
PRO   CB   C N N 325 
PRO   CG   C N N 326 
PRO   CD   C N N 327 
PRO   OXT  O N N 328 
PRO   H    H N N 329 
PRO   HA   H N N 330 
PRO   HB2  H N N 331 
PRO   HB3  H N N 332 
PRO   HG2  H N N 333 
PRO   HG3  H N N 334 
PRO   HD2  H N N 335 
PRO   HD3  H N N 336 
PRO   HXT  H N N 337 
SER   N    N N N 338 
SER   CA   C N S 339 
SER   C    C N N 340 
SER   O    O N N 341 
SER   CB   C N N 342 
SER   OG   O N N 343 
SER   OXT  O N N 344 
SER   H    H N N 345 
SER   H2   H N N 346 
SER   HA   H N N 347 
SER   HB2  H N N 348 
SER   HB3  H N N 349 
SER   HG   H N N 350 
SER   HXT  H N N 351 
THR   N    N N N 352 
THR   CA   C N S 353 
THR   C    C N N 354 
THR   O    O N N 355 
THR   CB   C N R 356 
THR   OG1  O N N 357 
THR   CG2  C N N 358 
THR   OXT  O N N 359 
THR   H    H N N 360 
THR   H2   H N N 361 
THR   HA   H N N 362 
THR   HB   H N N 363 
THR   HG1  H N N 364 
THR   HG21 H N N 365 
THR   HG22 H N N 366 
THR   HG23 H N N 367 
THR   HXT  H N N 368 
TRP   N    N N N 369 
TRP   CA   C N S 370 
TRP   C    C N N 371 
TRP   O    O N N 372 
TRP   CB   C N N 373 
TRP   CG   C Y N 374 
TRP   CD1  C Y N 375 
TRP   CD2  C Y N 376 
TRP   NE1  N Y N 377 
TRP   CE2  C Y N 378 
TRP   CE3  C Y N 379 
TRP   CZ2  C Y N 380 
TRP   CZ3  C Y N 381 
TRP   CH2  C Y N 382 
TRP   OXT  O N N 383 
TRP   H    H N N 384 
TRP   H2   H N N 385 
TRP   HA   H N N 386 
TRP   HB2  H N N 387 
TRP   HB3  H N N 388 
TRP   HD1  H N N 389 
TRP   HE1  H N N 390 
TRP   HE3  H N N 391 
TRP   HZ2  H N N 392 
TRP   HZ3  H N N 393 
TRP   HH2  H N N 394 
TRP   HXT  H N N 395 
TYR   N    N N N 396 
TYR   CA   C N S 397 
TYR   C    C N N 398 
TYR   O    O N N 399 
TYR   CB   C N N 400 
TYR   CG   C Y N 401 
TYR   CD1  C Y N 402 
TYR   CD2  C Y N 403 
TYR   CE1  C Y N 404 
TYR   CE2  C Y N 405 
TYR   CZ   C Y N 406 
TYR   OH   O N N 407 
TYR   OXT  O N N 408 
TYR   H    H N N 409 
TYR   H2   H N N 410 
TYR   HA   H N N 411 
TYR   HB2  H N N 412 
TYR   HB3  H N N 413 
TYR   HD1  H N N 414 
TYR   HD2  H N N 415 
TYR   HE1  H N N 416 
TYR   HE2  H N N 417 
TYR   HH   H N N 418 
TYR   HXT  H N N 419 
VAL   N    N N N 420 
VAL   CA   C N S 421 
VAL   C    C N N 422 
VAL   O    O N N 423 
VAL   CB   C N N 424 
VAL   CG1  C N N 425 
VAL   CG2  C N N 426 
VAL   OXT  O N N 427 
VAL   H    H N N 428 
VAL   H2   H N N 429 
VAL   HA   H N N 430 
VAL   HB   H N N 431 
VAL   HG11 H N N 432 
VAL   HG12 H N N 433 
VAL   HG13 H N N 434 
VAL   HG21 H N N 435 
VAL   HG22 H N N 436 
VAL   HG23 H N N 437 
VAL   HXT  H N N 438 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1ISA C1  C2   sing N N 1   
A1ISA O1  C5   doub N N 2   
A1ISA C4  C5   sing N N 3   
A1ISA C4  C3   doub N N 4   
A1ISA C2  C3   sing N N 5   
A1ISA C5  N1   sing N N 6   
A1ISA C3  C22  sing N N 7   
A1ISA N1  C6   sing N N 8   
A1ISA N1  C12  sing N N 9   
A1ISA C22 C12  doub Y N 10  
A1ISA C22 C21  sing Y N 11  
A1ISA C6  C11  doub Y N 12  
A1ISA C6  C7   sing Y N 13  
A1ISA C12 N2   sing Y N 14  
A1ISA C11 C10  sing Y N 15  
A1ISA C7  C8   doub Y N 16  
A1ISA C21 N4   doub Y N 17  
A1ISA C10 C9   doub Y N 18  
A1ISA C8  C9   sing Y N 19  
A1ISA N2  C13  doub Y N 20  
A1ISA N4  C13  sing Y N 21  
A1ISA C13 N3   sing N N 22  
A1ISA N3  C14  sing N N 23  
A1ISA C15 C14  doub Y N 24  
A1ISA C15 C16  sing Y N 25  
A1ISA C14 C19  sing Y N 26  
A1ISA C16 C17  doub Y N 27  
A1ISA C19 O2   sing N N 28  
A1ISA C19 C18  doub Y N 29  
A1ISA C17 C18  sing Y N 30  
A1ISA O2  C20  sing N N 31  
A1ISA C4  H4   sing N N 32  
A1ISA C11 H9   sing N N 33  
A1ISA C7  H5   sing N N 34  
A1ISA C8  H6   sing N N 35  
A1ISA C9  H7   sing N N 36  
A1ISA C10 H8   sing N N 37  
A1ISA N3  H10  sing N N 38  
A1ISA C1  H1   sing N N 39  
A1ISA C1  H2   sing N N 40  
A1ISA C2  H3   sing N N 41  
A1ISA C15 H11  sing N N 42  
A1ISA C16 H12  sing N N 43  
A1ISA C17 H13  sing N N 44  
A1ISA C18 H14  sing N N 45  
A1ISA C20 H16  sing N N 46  
A1ISA C20 H17  sing N N 47  
A1ISA C20 H15  sing N N 48  
A1ISA C21 H18  sing N N 49  
A1ISA C1  H19  sing N N 50  
A1ISA C2  H20  sing N N 51  
ALA   N   CA   sing N N 52  
ALA   N   H    sing N N 53  
ALA   N   H2   sing N N 54  
ALA   CA  C    sing N N 55  
ALA   CA  CB   sing N N 56  
ALA   CA  HA   sing N N 57  
ALA   C   O    doub N N 58  
ALA   C   OXT  sing N N 59  
ALA   CB  HB1  sing N N 60  
ALA   CB  HB2  sing N N 61  
ALA   CB  HB3  sing N N 62  
ALA   OXT HXT  sing N N 63  
ARG   N   CA   sing N N 64  
ARG   N   H    sing N N 65  
ARG   N   H2   sing N N 66  
ARG   CA  C    sing N N 67  
ARG   CA  CB   sing N N 68  
ARG   CA  HA   sing N N 69  
ARG   C   O    doub N N 70  
ARG   C   OXT  sing N N 71  
ARG   CB  CG   sing N N 72  
ARG   CB  HB2  sing N N 73  
ARG   CB  HB3  sing N N 74  
ARG   CG  CD   sing N N 75  
ARG   CG  HG2  sing N N 76  
ARG   CG  HG3  sing N N 77  
ARG   CD  NE   sing N N 78  
ARG   CD  HD2  sing N N 79  
ARG   CD  HD3  sing N N 80  
ARG   NE  CZ   sing N N 81  
ARG   NE  HE   sing N N 82  
ARG   CZ  NH1  sing N N 83  
ARG   CZ  NH2  doub N N 84  
ARG   NH1 HH11 sing N N 85  
ARG   NH1 HH12 sing N N 86  
ARG   NH2 HH21 sing N N 87  
ARG   NH2 HH22 sing N N 88  
ARG   OXT HXT  sing N N 89  
ASN   N   CA   sing N N 90  
ASN   N   H    sing N N 91  
ASN   N   H2   sing N N 92  
ASN   CA  C    sing N N 93  
ASN   CA  CB   sing N N 94  
ASN   CA  HA   sing N N 95  
ASN   C   O    doub N N 96  
ASN   C   OXT  sing N N 97  
ASN   CB  CG   sing N N 98  
ASN   CB  HB2  sing N N 99  
ASN   CB  HB3  sing N N 100 
ASN   CG  OD1  doub N N 101 
ASN   CG  ND2  sing N N 102 
ASN   ND2 HD21 sing N N 103 
ASN   ND2 HD22 sing N N 104 
ASN   OXT HXT  sing N N 105 
ASP   N   CA   sing N N 106 
ASP   N   H    sing N N 107 
ASP   N   H2   sing N N 108 
ASP   CA  C    sing N N 109 
ASP   CA  CB   sing N N 110 
ASP   CA  HA   sing N N 111 
ASP   C   O    doub N N 112 
ASP   C   OXT  sing N N 113 
ASP   CB  CG   sing N N 114 
ASP   CB  HB2  sing N N 115 
ASP   CB  HB3  sing N N 116 
ASP   CG  OD1  doub N N 117 
ASP   CG  OD2  sing N N 118 
ASP   OD2 HD2  sing N N 119 
ASP   OXT HXT  sing N N 120 
CYS   N   CA   sing N N 121 
CYS   N   H    sing N N 122 
CYS   N   H2   sing N N 123 
CYS   CA  C    sing N N 124 
CYS   CA  CB   sing N N 125 
CYS   CA  HA   sing N N 126 
CYS   C   O    doub N N 127 
CYS   C   OXT  sing N N 128 
CYS   CB  SG   sing N N 129 
CYS   CB  HB2  sing N N 130 
CYS   CB  HB3  sing N N 131 
CYS   SG  HG   sing N N 132 
CYS   OXT HXT  sing N N 133 
GLN   N   CA   sing N N 134 
GLN   N   H    sing N N 135 
GLN   N   H2   sing N N 136 
GLN   CA  C    sing N N 137 
GLN   CA  CB   sing N N 138 
GLN   CA  HA   sing N N 139 
GLN   C   O    doub N N 140 
GLN   C   OXT  sing N N 141 
GLN   CB  CG   sing N N 142 
GLN   CB  HB2  sing N N 143 
GLN   CB  HB3  sing N N 144 
GLN   CG  CD   sing N N 145 
GLN   CG  HG2  sing N N 146 
GLN   CG  HG3  sing N N 147 
GLN   CD  OE1  doub N N 148 
GLN   CD  NE2  sing N N 149 
GLN   NE2 HE21 sing N N 150 
GLN   NE2 HE22 sing N N 151 
GLN   OXT HXT  sing N N 152 
GLU   N   CA   sing N N 153 
GLU   N   H    sing N N 154 
GLU   N   H2   sing N N 155 
GLU   CA  C    sing N N 156 
GLU   CA  CB   sing N N 157 
GLU   CA  HA   sing N N 158 
GLU   C   O    doub N N 159 
GLU   C   OXT  sing N N 160 
GLU   CB  CG   sing N N 161 
GLU   CB  HB2  sing N N 162 
GLU   CB  HB3  sing N N 163 
GLU   CG  CD   sing N N 164 
GLU   CG  HG2  sing N N 165 
GLU   CG  HG3  sing N N 166 
GLU   CD  OE1  doub N N 167 
GLU   CD  OE2  sing N N 168 
GLU   OE2 HE2  sing N N 169 
GLU   OXT HXT  sing N N 170 
GLY   N   CA   sing N N 171 
GLY   N   H    sing N N 172 
GLY   N   H2   sing N N 173 
GLY   CA  C    sing N N 174 
GLY   CA  HA2  sing N N 175 
GLY   CA  HA3  sing N N 176 
GLY   C   O    doub N N 177 
GLY   C   OXT  sing N N 178 
GLY   OXT HXT  sing N N 179 
HIS   N   CA   sing N N 180 
HIS   N   H    sing N N 181 
HIS   N   H2   sing N N 182 
HIS   CA  C    sing N N 183 
HIS   CA  CB   sing N N 184 
HIS   CA  HA   sing N N 185 
HIS   C   O    doub N N 186 
HIS   C   OXT  sing N N 187 
HIS   CB  CG   sing N N 188 
HIS   CB  HB2  sing N N 189 
HIS   CB  HB3  sing N N 190 
HIS   CG  ND1  sing Y N 191 
HIS   CG  CD2  doub Y N 192 
HIS   ND1 CE1  doub Y N 193 
HIS   ND1 HD1  sing N N 194 
HIS   CD2 NE2  sing Y N 195 
HIS   CD2 HD2  sing N N 196 
HIS   CE1 NE2  sing Y N 197 
HIS   CE1 HE1  sing N N 198 
HIS   NE2 HE2  sing N N 199 
HIS   OXT HXT  sing N N 200 
HOH   O   H1   sing N N 201 
HOH   O   H2   sing N N 202 
ILE   N   CA   sing N N 203 
ILE   N   H    sing N N 204 
ILE   N   H2   sing N N 205 
ILE   CA  C    sing N N 206 
ILE   CA  CB   sing N N 207 
ILE   CA  HA   sing N N 208 
ILE   C   O    doub N N 209 
ILE   C   OXT  sing N N 210 
ILE   CB  CG1  sing N N 211 
ILE   CB  CG2  sing N N 212 
ILE   CB  HB   sing N N 213 
ILE   CG1 CD1  sing N N 214 
ILE   CG1 HG12 sing N N 215 
ILE   CG1 HG13 sing N N 216 
ILE   CG2 HG21 sing N N 217 
ILE   CG2 HG22 sing N N 218 
ILE   CG2 HG23 sing N N 219 
ILE   CD1 HD11 sing N N 220 
ILE   CD1 HD12 sing N N 221 
ILE   CD1 HD13 sing N N 222 
ILE   OXT HXT  sing N N 223 
LEU   N   CA   sing N N 224 
LEU   N   H    sing N N 225 
LEU   N   H2   sing N N 226 
LEU   CA  C    sing N N 227 
LEU   CA  CB   sing N N 228 
LEU   CA  HA   sing N N 229 
LEU   C   O    doub N N 230 
LEU   C   OXT  sing N N 231 
LEU   CB  CG   sing N N 232 
LEU   CB  HB2  sing N N 233 
LEU   CB  HB3  sing N N 234 
LEU   CG  CD1  sing N N 235 
LEU   CG  CD2  sing N N 236 
LEU   CG  HG   sing N N 237 
LEU   CD1 HD11 sing N N 238 
LEU   CD1 HD12 sing N N 239 
LEU   CD1 HD13 sing N N 240 
LEU   CD2 HD21 sing N N 241 
LEU   CD2 HD22 sing N N 242 
LEU   CD2 HD23 sing N N 243 
LEU   OXT HXT  sing N N 244 
LYS   N   CA   sing N N 245 
LYS   N   H    sing N N 246 
LYS   N   H2   sing N N 247 
LYS   CA  C    sing N N 248 
LYS   CA  CB   sing N N 249 
LYS   CA  HA   sing N N 250 
LYS   C   O    doub N N 251 
LYS   C   OXT  sing N N 252 
LYS   CB  CG   sing N N 253 
LYS   CB  HB2  sing N N 254 
LYS   CB  HB3  sing N N 255 
LYS   CG  CD   sing N N 256 
LYS   CG  HG2  sing N N 257 
LYS   CG  HG3  sing N N 258 
LYS   CD  CE   sing N N 259 
LYS   CD  HD2  sing N N 260 
LYS   CD  HD3  sing N N 261 
LYS   CE  NZ   sing N N 262 
LYS   CE  HE2  sing N N 263 
LYS   CE  HE3  sing N N 264 
LYS   NZ  HZ1  sing N N 265 
LYS   NZ  HZ2  sing N N 266 
LYS   NZ  HZ3  sing N N 267 
LYS   OXT HXT  sing N N 268 
MET   N   CA   sing N N 269 
MET   N   H    sing N N 270 
MET   N   H2   sing N N 271 
MET   CA  C    sing N N 272 
MET   CA  CB   sing N N 273 
MET   CA  HA   sing N N 274 
MET   C   O    doub N N 275 
MET   C   OXT  sing N N 276 
MET   CB  CG   sing N N 277 
MET   CB  HB2  sing N N 278 
MET   CB  HB3  sing N N 279 
MET   CG  SD   sing N N 280 
MET   CG  HG2  sing N N 281 
MET   CG  HG3  sing N N 282 
MET   SD  CE   sing N N 283 
MET   CE  HE1  sing N N 284 
MET   CE  HE2  sing N N 285 
MET   CE  HE3  sing N N 286 
MET   OXT HXT  sing N N 287 
PHE   N   CA   sing N N 288 
PHE   N   H    sing N N 289 
PHE   N   H2   sing N N 290 
PHE   CA  C    sing N N 291 
PHE   CA  CB   sing N N 292 
PHE   CA  HA   sing N N 293 
PHE   C   O    doub N N 294 
PHE   C   OXT  sing N N 295 
PHE   CB  CG   sing N N 296 
PHE   CB  HB2  sing N N 297 
PHE   CB  HB3  sing N N 298 
PHE   CG  CD1  doub Y N 299 
PHE   CG  CD2  sing Y N 300 
PHE   CD1 CE1  sing Y N 301 
PHE   CD1 HD1  sing N N 302 
PHE   CD2 CE2  doub Y N 303 
PHE   CD2 HD2  sing N N 304 
PHE   CE1 CZ   doub Y N 305 
PHE   CE1 HE1  sing N N 306 
PHE   CE2 CZ   sing Y N 307 
PHE   CE2 HE2  sing N N 308 
PHE   CZ  HZ   sing N N 309 
PHE   OXT HXT  sing N N 310 
PRO   N   CA   sing N N 311 
PRO   N   CD   sing N N 312 
PRO   N   H    sing N N 313 
PRO   CA  C    sing N N 314 
PRO   CA  CB   sing N N 315 
PRO   CA  HA   sing N N 316 
PRO   C   O    doub N N 317 
PRO   C   OXT  sing N N 318 
PRO   CB  CG   sing N N 319 
PRO   CB  HB2  sing N N 320 
PRO   CB  HB3  sing N N 321 
PRO   CG  CD   sing N N 322 
PRO   CG  HG2  sing N N 323 
PRO   CG  HG3  sing N N 324 
PRO   CD  HD2  sing N N 325 
PRO   CD  HD3  sing N N 326 
PRO   OXT HXT  sing N N 327 
SER   N   CA   sing N N 328 
SER   N   H    sing N N 329 
SER   N   H2   sing N N 330 
SER   CA  C    sing N N 331 
SER   CA  CB   sing N N 332 
SER   CA  HA   sing N N 333 
SER   C   O    doub N N 334 
SER   C   OXT  sing N N 335 
SER   CB  OG   sing N N 336 
SER   CB  HB2  sing N N 337 
SER   CB  HB3  sing N N 338 
SER   OG  HG   sing N N 339 
SER   OXT HXT  sing N N 340 
THR   N   CA   sing N N 341 
THR   N   H    sing N N 342 
THR   N   H2   sing N N 343 
THR   CA  C    sing N N 344 
THR   CA  CB   sing N N 345 
THR   CA  HA   sing N N 346 
THR   C   O    doub N N 347 
THR   C   OXT  sing N N 348 
THR   CB  OG1  sing N N 349 
THR   CB  CG2  sing N N 350 
THR   CB  HB   sing N N 351 
THR   OG1 HG1  sing N N 352 
THR   CG2 HG21 sing N N 353 
THR   CG2 HG22 sing N N 354 
THR   CG2 HG23 sing N N 355 
THR   OXT HXT  sing N N 356 
TRP   N   CA   sing N N 357 
TRP   N   H    sing N N 358 
TRP   N   H2   sing N N 359 
TRP   CA  C    sing N N 360 
TRP   CA  CB   sing N N 361 
TRP   CA  HA   sing N N 362 
TRP   C   O    doub N N 363 
TRP   C   OXT  sing N N 364 
TRP   CB  CG   sing N N 365 
TRP   CB  HB2  sing N N 366 
TRP   CB  HB3  sing N N 367 
TRP   CG  CD1  doub Y N 368 
TRP   CG  CD2  sing Y N 369 
TRP   CD1 NE1  sing Y N 370 
TRP   CD1 HD1  sing N N 371 
TRP   CD2 CE2  doub Y N 372 
TRP   CD2 CE3  sing Y N 373 
TRP   NE1 CE2  sing Y N 374 
TRP   NE1 HE1  sing N N 375 
TRP   CE2 CZ2  sing Y N 376 
TRP   CE3 CZ3  doub Y N 377 
TRP   CE3 HE3  sing N N 378 
TRP   CZ2 CH2  doub Y N 379 
TRP   CZ2 HZ2  sing N N 380 
TRP   CZ3 CH2  sing Y N 381 
TRP   CZ3 HZ3  sing N N 382 
TRP   CH2 HH2  sing N N 383 
TRP   OXT HXT  sing N N 384 
TYR   N   CA   sing N N 385 
TYR   N   H    sing N N 386 
TYR   N   H2   sing N N 387 
TYR   CA  C    sing N N 388 
TYR   CA  CB   sing N N 389 
TYR   CA  HA   sing N N 390 
TYR   C   O    doub N N 391 
TYR   C   OXT  sing N N 392 
TYR   CB  CG   sing N N 393 
TYR   CB  HB2  sing N N 394 
TYR   CB  HB3  sing N N 395 
TYR   CG  CD1  doub Y N 396 
TYR   CG  CD2  sing Y N 397 
TYR   CD1 CE1  sing Y N 398 
TYR   CD1 HD1  sing N N 399 
TYR   CD2 CE2  doub Y N 400 
TYR   CD2 HD2  sing N N 401 
TYR   CE1 CZ   doub Y N 402 
TYR   CE1 HE1  sing N N 403 
TYR   CE2 CZ   sing Y N 404 
TYR   CE2 HE2  sing N N 405 
TYR   CZ  OH   sing N N 406 
TYR   OH  HH   sing N N 407 
TYR   OXT HXT  sing N N 408 
VAL   N   CA   sing N N 409 
VAL   N   H    sing N N 410 
VAL   N   H2   sing N N 411 
VAL   CA  C    sing N N 412 
VAL   CA  CB   sing N N 413 
VAL   CA  HA   sing N N 414 
VAL   C   O    doub N N 415 
VAL   C   OXT  sing N N 416 
VAL   CB  CG1  sing N N 417 
VAL   CB  CG2  sing N N 418 
VAL   CB  HB   sing N N 419 
VAL   CG1 HG11 sing N N 420 
VAL   CG1 HG12 sing N N 421 
VAL   CG1 HG13 sing N N 422 
VAL   CG2 HG21 sing N N 423 
VAL   CG2 HG22 sing N N 424 
VAL   CG2 HG23 sing N N 425 
VAL   OXT HXT  sing N N 426 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Cancer Research UK'                             'United Kingdom' DRCDDRPGMApr2020100002 1 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/X004872/1           2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8SC7 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9H46 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.006911 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006911 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006911 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
H 1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997 0.0030   
N 7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O 8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S 16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0325   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N N    . GLY   A 1 2   ? 7.916   -67.208 92.071  1   140.002 ? 696  GLY   A N    1 ? 
ATOM   2    C CA   . GLY   A 1 2   ? 8.968   -66.965 93.077  1   131.206 ? 696  GLY   A CA   1 ? 
ATOM   3    C C    . GLY   A 1 2   ? 8.4     -67.091 94.485  1   136.813 ? 696  GLY   A C    1 ? 
ATOM   4    O O    . GLY   A 1 2   ? 9.065   -67.615 95.372  1   150.795 ? 696  GLY   A O    1 ? 
ATOM   5    H H    . GLY   A 1 2   ? 8.298   -67.465 91.291  1   137.221 ? 696  GLY   A H    1 c 
ATOM   6    H HA2  . GLY   A 1 2   ? 9.695   -67.612 92.954  1   134.471 ? 696  GLY   A HA2  1 c 
ATOM   7    H HA3  . GLY   A 1 2   ? 9.339   -66.06  92.948  1   134.469 ? 696  GLY   A HA3  1 c 
ATOM   8    N N    . GLU   A 1 3   ? 7.159   -66.611 94.66   1   135.324 ? 697  GLU   A N    1 ? 
ATOM   9    C CA   . GLU   A 1 3   ? 6.523   -66.502 95.964  1   132.271 ? 697  GLU   A CA   1 ? 
ATOM   10   C C    . GLU   A 1 3   ? 5.084   -67.009 95.897  1   114.196 ? 697  GLU   A C    1 ? 
ATOM   11   O O    . GLU   A 1 3   ? 4.433   -66.911 94.858  1   104.01  ? 697  GLU   A O    1 ? 
ATOM   12   C CB   . GLU   A 1 3   ? 6.557   -65.05  96.446  1   144.695 ? 697  GLU   A CB   1 ? 
ATOM   13   C CG   . GLU   A 1 3   ? 7.62    -64.782 97.508  1   150.781 ? 697  GLU   A CG   1 ? 
ATOM   14   C CD   . GLU   A 1 3   ? 7.282   -65.397 98.858  1   152.872 ? 697  GLU   A CD   1 ? 
ATOM   15   O OE1  . GLU   A 1 3   ? 6.812   -66.559 98.885  1   144.812 ? 697  GLU   A OE1  1 ? 
ATOM   16   O OE2  . GLU   A 1 3   ? 7.501   -64.702 99.886  1   135.384 ? 697  GLU   A OE2  1 ? 
ATOM   17   H H    . GLU   A 1 3   ? 6.689   -66.328 93.93   1   134.886 ? 697  GLU   A H    1 c 
ATOM   18   H HA   . GLU   A 1 3   ? 7.024   -67.069 96.6    1   131.678 ? 697  GLU   A HA   1 c 
ATOM   19   H HB2  . GLU   A 1 3   ? 6.728   -64.47  95.676  1   143.013 ? 697  GLU   A HB2  1 c 
ATOM   20   H HB3  . GLU   A 1 3   ? 5.677   -64.812 96.808  1   142.899 ? 697  GLU   A HB3  1 c 
ATOM   21   H HG2  . GLU   A 1 3   ? 8.479   -65.146 97.203  1   149.833 ? 697  GLU   A HG2  1 c 
ATOM   22   H HG3  . GLU   A 1 3   ? 7.726   -63.814 97.62   1   149.756 ? 697  GLU   A HG3  1 c 
ATOM   23   N N    . ALA   A 1 4   ? 4.596   -67.557 97.018  1   111.604 ? 698  ALA   A N    1 ? 
ATOM   24   C CA   . ALA   A 1 4   ? 3.228   -68.045 97.109  1   104.626 ? 698  ALA   A CA   1 ? 
ATOM   25   C C    . ALA   A 1 4   ? 2.272   -66.871 97.303  1   106.62  ? 698  ALA   A C    1 ? 
ATOM   26   O O    . ALA   A 1 4   ? 2.62    -65.873 97.93   1   106.126 ? 698  ALA   A O    1 ? 
ATOM   27   C CB   . ALA   A 1 4   ? 3.074   -69.045 98.235  1   98.444  ? 698  ALA   A CB   1 ? 
ATOM   28   H H    . ALA   A 1 4   ? 5.136   -67.627 97.751  1   110.801 ? 698  ALA   A H    1 c 
ATOM   29   H HA   . ALA   A 1 4   ? 3.008   -68.494 96.25   1   105.098 ? 698  ALA   A HA   1 c 
ATOM   30   H HB1  . ALA   A 1 4   ? 3.656   -69.807 98.077  1   100.235 ? 698  ALA   A HB1  1 c 
ATOM   31   H HB2  . ALA   A 1 4   ? 3.315   -68.627 99.078  1   100.235 ? 698  ALA   A HB2  1 c 
ATOM   32   H HB3  . ALA   A 1 4   ? 2.152   -69.349 98.279  1   100.235 ? 698  ALA   A HB3  1 c 
ATOM   33   N N    . PRO   A 1 5   ? 1.074   -66.934 96.686  1   100.152 ? 699  PRO   A N    1 ? 
ATOM   34   C CA   . PRO   A 1 5   ? 0.02    -65.948 96.878  1   100.454 ? 699  PRO   A CA   1 ? 
ATOM   35   C C    . PRO   A 1 5   ? -0.385  -65.721 98.319  1   89.47   ? 699  PRO   A C    1 ? 
ATOM   36   O O    . PRO   A 1 5   ? -0.626  -66.679 99.021  1   109.717 ? 699  PRO   A O    1 ? 
ATOM   37   C CB   . PRO   A 1 5   ? -1.19   -66.521 96.14   1   100.236 ? 699  PRO   A CB   1 ? 
ATOM   38   C CG   . PRO   A 1 5   ? -0.761  -67.889 95.682  1   102.891 ? 699  PRO   A CG   1 ? 
ATOM   39   C CD   . PRO   A 1 5   ? 0.732   -67.886 95.627  1   102.192 ? 699  PRO   A CD   1 ? 
ATOM   40   H HA   . PRO   A 1 5   ? 0.291   -65.102 96.474  1   98.19   ? 699  PRO   A HA   1 c 
ATOM   41   H HB2  . PRO   A 1 5   ? -1.965  -66.582 96.733  1   100.852 ? 699  PRO   A HB2  1 c 
ATOM   42   H HB3  . PRO   A 1 5   ? -1.429  -65.961 95.377  1   100.879 ? 699  PRO   A HB3  1 c 
ATOM   43   H HG2  . PRO   A 1 5   ? -1.074  -68.573 96.307  1   102.122 ? 699  PRO   A HG2  1 c 
ATOM   44   H HG3  . PRO   A 1 5   ? -1.131  -68.086 94.798  1   102.122 ? 699  PRO   A HG3  1 c 
ATOM   45   H HD2  . PRO   A 1 5   ? 1.092   -68.773 95.818  1   101.915 ? 699  PRO   A HD2  1 c 
ATOM   46   H HD3  . PRO   A 1 5   ? 1.06    -67.58  94.76   1   101.878 ? 699  PRO   A HD3  1 c 
ATOM   47   N N    . ASN   A 1 6   ? -0.513  -64.451 98.71   1   96.346  ? 700  ASN   A N    1 ? 
ATOM   48   C CA   . ASN   A 1 6   ? -0.888  -64.085 100.065 1   94.017  ? 700  ASN   A CA   1 ? 
ATOM   49   C C    . ASN   A 1 6   ? -2.403  -63.939 100.162 1   89.745  ? 700  ASN   A C    1 ? 
ATOM   50   O O    . ASN   A 1 6   ? -2.948  -62.89  99.852  1   100.413 ? 700  ASN   A O    1 ? 
ATOM   51   C CB   . ASN   A 1 6   ? -0.192  -62.8   100.49  1   92.706  ? 700  ASN   A CB   1 ? 
ATOM   52   C CG   . ASN   A 1 6   ? -0.489  -62.456 101.926 1   87.919  ? 700  ASN   A CG   1 ? 
ATOM   53   O OD1  . ASN   A 1 6   ? -1.229  -63.174 102.608 1   77.397  ? 700  ASN   A OD1  1 ? 
ATOM   54   N ND2  . ASN   A 1 6   ? 0.063   -61.344 102.38  1   90.891  ? 700  ASN   A ND2  1 ? 
ATOM   55   H H    . ASN   A 1 6   ? -0.361  -63.783 98.106  1   94.205  ? 700  ASN   A H    1 c 
ATOM   56   H HA   . ASN   A 1 6   ? -0.594  -64.799 100.675 1   93.402  ? 700  ASN   A HA   1 c 
ATOM   57   H HB2  . ASN   A 1 6   ? 0.774   -62.905 100.378 1   91.882  ? 700  ASN   A HB2  1 c 
ATOM   58   H HB3  . ASN   A 1 6   ? -0.486  -62.066 99.915  1   91.918  ? 700  ASN   A HB3  1 c 
ATOM   59   H HD21 . ASN   A 1 6   ? -0.316  -60.904 103.05  1   90.031  ? 700  ASN   A HD21 1 c 
ATOM   60   H HD22 . ASN   A 1 6   ? 0.813   -61.04  102.016 1   89.999  ? 700  ASN   A HD22 1 c 
ATOM   61   N N    . GLN   A 1 7   ? -3.074  -64.982 100.651 1   94.718  ? 701  GLN   A N    1 ? 
ATOM   62   C CA   . GLN   A 1 7   ? -4.519  -65.075 100.58  1   93.476  ? 701  GLN   A CA   1 ? 
ATOM   63   C C    . GLN   A 1 7   ? -5.124  -64.705 101.923 1   86.511  ? 701  GLN   A C    1 ? 
ATOM   64   O O    . GLN   A 1 7   ? -6.23   -65.12  102.222 1   98.279  ? 701  GLN   A O    1 ? 
ATOM   65   C CB   . GLN   A 1 7   ? -4.927  -66.497 100.204 1   103.369 ? 701  GLN   A CB   1 ? 
ATOM   66   C CG   . GLN   A 1 7   ? -4.238  -66.999 98.942  1   111.838 ? 701  GLN   A CG   1 ? 
ATOM   67   C CD   . GLN   A 1 7   ? -4.7    -68.374 98.528  1   102.163 ? 701  GLN   A CD   1 ? 
ATOM   68   O OE1  . GLN   A 1 7   ? -5.889  -68.607 98.304  1   98.702  ? 701  GLN   A OE1  1 ? 
ATOM   69   N NE2  . GLN   A 1 7   ? -3.76   -69.297 98.419  1   103.961 ? 701  GLN   A NE2  1 ? 
ATOM   70   H H    . GLN   A 1 7   ? -2.611  -65.664 101.046 1   93.237  ? 701  GLN   A H    1 c 
ATOM   71   H HA   . GLN   A 1 7   ? -4.849  -64.445 99.89   1   94.107  ? 701  GLN   A HA   1 c 
ATOM   72   H HB2  . GLN   A 1 7   ? -4.711  -67.097 100.948 1   102.752 ? 701  GLN   A HB2  1 c 
ATOM   73   H HB3  . GLN   A 1 7   ? -5.898  -66.524 100.069 1   102.811 ? 701  GLN   A HB3  1 c 
ATOM   74   H HG2  . GLN   A 1 7   ? -4.412  -66.373 98.208  1   107.568 ? 701  GLN   A HG2  1 c 
ATOM   75   H HG3  . GLN   A 1 7   ? -3.269  -67.022 99.09   1   107.475 ? 701  GLN   A HG3  1 c 
ATOM   76   H HE21 . GLN   A 1 7   ? -3.944  -70.141 98.634  1   103.427 ? 701  GLN   A HE21 1 c 
ATOM   77   H HE22 . GLN   A 1 7   ? -2.948  -69.075 98.128  1   103.496 ? 701  GLN   A HE22 1 c 
ATOM   78   N N    . ALA   A 1 8   ? -4.401  -63.908 102.712 1   79.998  ? 702  ALA   A N    1 ? 
ATOM   79   C CA   . ALA   A 1 8   ? -4.912  -63.392 103.965 1   84.756  ? 702  ALA   A CA   1 ? 
ATOM   80   C C    . ALA   A 1 8   ? -6.202  -62.616 103.729 1   81.326  ? 702  ALA   A C    1 ? 
ATOM   81   O O    . ALA   A 1 8   ? -6.333  -61.974 102.701 1   92.649  ? 702  ALA   A O    1 ? 
ATOM   82   C CB   . ALA   A 1 8   ? -3.871  -62.501 104.588 1   91.903  ? 702  ALA   A CB   1 ? 
ATOM   83   H H    . ALA   A 1 8   ? -3.554  -63.677 102.46  1   82.842  ? 702  ALA   A H    1 c 
ATOM   84   H HA   . ALA   A 1 8   ? -5.103  -64.159 104.572 1   84.426  ? 702  ALA   A HA   1 c 
ATOM   85   H HB1  . ALA   A 1 8   ? -3.06   -63.011 104.753 1   89.732  ? 702  ALA   A HB1  1 c 
ATOM   86   H HB2  . ALA   A 1 8   ? -3.67   -61.763 103.987 1   89.716  ? 702  ALA   A HB2  1 c 
ATOM   87   H HB3  . ALA   A 1 8   ? -4.205  -62.147 105.429 1   89.716  ? 702  ALA   A HB3  1 c 
ATOM   88   N N    . LEU   A 1 9   ? -7.116  -62.661 104.703 1   85.453  ? 703  LEU   A N    1 ? 
ATOM   89   C CA   . LEU   A 1 9   ? -8.35   -61.895 104.668 1   88.878  ? 703  LEU   A CA   1 ? 
ATOM   90   C C    . LEU   A 1 9   ? -8.119  -60.57  105.379 1   90.938  ? 703  LEU   A C    1 ? 
ATOM   91   O O    . LEU   A 1 9   ? -7.55   -60.549 106.46  1   85.336  ? 703  LEU   A O    1 ? 
ATOM   92   C CB   . LEU   A 1 9   ? -9.527  -62.609 105.332 1   90.607  ? 703  LEU   A CB   1 ? 
ATOM   93   C CG   . LEU   A 1 9   ? -10.277 -63.657 104.509 1   96.052  ? 703  LEU   A CG   1 ? 
ATOM   94   C CD1  . LEU   A 1 9   ? -9.938  -63.629 103.028 1   93.171  ? 703  LEU   A CD1  1 ? 
ATOM   95   C CD2  . LEU   A 1 9   ? -10.067 -65.048 105.099 1   118.375 ? 703  LEU   A CD2  1 ? 
ATOM   96   H H    . LEU   A 1 9   ? -6.961  -63.198 105.427 1   85.245  ? 703  LEU   A H    1 c 
ATOM   97   H HA   . LEU   A 1 9   ? -8.573  -61.705 103.725 1   89.08   ? 703  LEU   A HA   1 c 
ATOM   98   H HB2  . LEU   A 1 9   ? -9.195  -63.041 106.153 1   91.635  ? 703  LEU   A HB2  1 c 
ATOM   99   H HB3  . LEU   A 1 9   ? -10.176 -61.925 105.618 1   91.456  ? 703  LEU   A HB3  1 c 
ATOM   100  H HG   . LEU   A 1 9   ? -11.246 -63.455 104.586 1   98.247  ? 703  LEU   A HG   1 c 
ATOM   101  H HD11 . LEU   A 1 9   ? -10.142 -62.752 102.662 1   93.93   ? 703  LEU   A HD11 1 c 
ATOM   102  H HD12 . LEU   A 1 9   ? -10.465 -64.301 102.563 1   93.982  ? 703  LEU   A HD12 1 c 
ATOM   103  H HD13 . LEU   A 1 9   ? -8.993  -63.821 102.905 1   93.931  ? 703  LEU   A HD13 1 c 
ATOM   104  H HD21 . LEU   A 1 9   ? -10.415 -65.073 106.006 1   111.13  ? 703  LEU   A HD21 1 c 
ATOM   105  H HD22 . LEU   A 1 9   ? -9.118  -65.256 105.111 1   111.243 ? 703  LEU   A HD22 1 c 
ATOM   106  H HD23 . LEU   A 1 9   ? -10.535 -65.704 104.555 1   111.242 ? 703  LEU   A HD23 1 c 
ATOM   107  N N    . LEU   A 1 10  ? -8.584  -59.476 104.774 1   100.773 ? 704  LEU   A N    1 ? 
ATOM   108  C CA   . LEU   A 1 10  ? -8.602  -58.199 105.453 1   102.999 ? 704  LEU   A CA   1 ? 
ATOM   109  C C    . LEU   A 1 10  ? -10.049 -57.86  105.731 1   96.896  ? 704  LEU   A C    1 ? 
ATOM   110  O O    . LEU   A 1 10  ? -10.828 -57.761 104.79  1   102.202 ? 704  LEU   A O    1 ? 
ATOM   111  C CB   . LEU   A 1 10  ? -7.982  -57.101 104.604 1   110.477 ? 704  LEU   A CB   1 ? 
ATOM   112  C CG   . LEU   A 1 10  ? -7.947  -55.728 105.275 1   117.538 ? 704  LEU   A CG   1 ? 
ATOM   113  C CD1  . LEU   A 1 10  ? -6.84   -55.648 106.309 1   121.256 ? 704  LEU   A CD1  1 ? 
ATOM   114  C CD2  . LEU   A 1 10  ? -7.801  -54.654 104.228 1   129.366 ? 704  LEU   A CD2  1 ? 
ATOM   115  H H    . LEU   A 1 10  ? -8.897  -59.526 103.917 1   98.661  ? 704  LEU   A H    1 c 
ATOM   116  H HA   . LEU   A 1 10  ? -8.108  -58.276 106.308 1   102.536 ? 704  LEU   A HA   1 c 
ATOM   117  H HB2  . LEU   A 1 10  ? -7.059  -57.365 104.382 1   110.385 ? 704  LEU   A HB2  1 c 
ATOM   118  H HB3  . LEU   A 1 10  ? -8.494  -57.03  103.766 1   110.351 ? 704  LEU   A HB3  1 c 
ATOM   119  H HG   . LEU   A 1 10  ? -8.811  -55.585 105.74  1   118.878 ? 704  LEU   A HG   1 c 
ATOM   120  H HD11 . LEU   A 1 10  ? -7.014  -56.284 107.022 1   120.02  ? 704  LEU   A HD11 1 c 
ATOM   121  H HD12 . LEU   A 1 10  ? -6.805  -54.751 106.678 1   120.194 ? 704  LEU   A HD12 1 c 
ATOM   122  H HD13 . LEU   A 1 10  ? -5.988  -55.858 105.89  1   120.067 ? 704  LEU   A HD13 1 c 
ATOM   123  H HD21 . LEU   A 1 10  ? -8.578  -54.662 103.643 1   125.608 ? 704  LEU   A HD21 1 c 
ATOM   124  H HD22 . LEU   A 1 10  ? -7      -54.818 103.703 1   125.695 ? 704  LEU   A HD22 1 c 
ATOM   125  H HD23 . LEU   A 1 10  ? -7.732  -53.786 104.661 1   125.694 ? 704  LEU   A HD23 1 c 
ATOM   126  N N    . ARG   A 1 11  ? -10.362 -57.641 107.009 1   94.591  ? 705  ARG   A N    1 ? 
ATOM   127  C CA   . ARG   A 1 11  ? -11.735 -57.461 107.432 1   103.949 ? 705  ARG   A CA   1 ? 
ATOM   128  C C    . ARG   A 1 11  ? -12.01  -55.974 107.649 1   98.285  ? 705  ARG   A C    1 ? 
ATOM   129  O O    . ARG   A 1 11  ? -11.242 -55.284 108.304 1   94.974  ? 705  ARG   A O    1 ? 
ATOM   130  C CB   . ARG   A 1 11  ? -11.996 -58.312 108.677 1   105.154 ? 705  ARG   A CB   1 ? 
ATOM   131  C CG   . ARG   A 1 11  ? -13.45  -58.731 108.82  1   114.715 ? 705  ARG   A CG   1 ? 
ATOM   132  C CD   . ARG   A 1 11  ? -13.672 -59.447 110.129 1   120.528 ? 705  ARG   A CD   1 ? 
ATOM   133  N NE   . ARG   A 1 11  ? -15.082 -59.396 110.529 1   132.531 ? 705  ARG   A NE   1 ? 
ATOM   134  C CZ   . ARG   A 1 11  ? -15.686 -60.296 111.299 1   139.477 ? 705  ARG   A CZ   1 ? 
ATOM   135  N NH1  . ARG   A 1 11  ? -15.018 -61.358 111.703 1   134.48  ? 705  ARG   A NH1  1 ? 
ATOM   136  N NH2  . ARG   A 1 11  ? -16.956 -60.149 111.649 1   153.52  ? 705  ARG   A NH2  1 ? 
ATOM   137  H H    . ARG   A 1 11  ? -9.699  -57.599 107.636 1   97.273  ? 705  ARG   A H    1 c 
ATOM   138  H HA   . ARG   A 1 11  ? -12.328 -57.789 106.71  1   101.28  ? 705  ARG   A HA   1 c 
ATOM   139  H HB2  . ARG   A 1 11  ? -11.436 -59.116 108.638 1   106.914 ? 705  ARG   A HB2  1 c 
ATOM   140  H HB3  . ARG   A 1 11  ? -11.733 -57.801 109.473 1   107.016 ? 705  ARG   A HB3  1 c 
ATOM   141  H HG2  . ARG   A 1 11  ? -14.025 -57.936 108.782 1   113.869 ? 705  ARG   A HG2  1 c 
ATOM   142  H HG3  . ARG   A 1 11  ? -13.693 -59.328 108.079 1   113.777 ? 705  ARG   A HG3  1 c 
ATOM   143  H HD2  . ARG   A 1 11  ? -13.394 -60.38  110.032 1   122.079 ? 705  ARG   A HD2  1 c 
ATOM   144  H HD3  . ARG   A 1 11  ? -13.123 -59.037 110.827 1   121.717 ? 705  ARG   A HD3  1 c 
ATOM   145  H HE   . ARG   A 1 11  ? -15.562 -58.726 110.245 1   131.241 ? 705  ARG   A HE   1 c 
ATOM   146  H HH11 . ARG   A 1 11  ? -14.649 -61.895 111.102 1   135.829 ? 705  ARG   A HH11 1 c 
ATOM   147  H HH12 . ARG   A 1 11  ? -14.946 -61.525 112.575 1   135.965 ? 705  ARG   A HH12 1 c 
ATOM   148  H HH21 . ARG   A 1 11  ? -17.401 -59.425 111.407 1   148.73  ? 705  ARG   A HH21 1 c 
ATOM   149  H HH22 . ARG   A 1 11  ? -17.355 -60.778 112.126 1   148.865 ? 705  ARG   A HH22 1 c 
ATOM   150  N N    . ILE   A 1 12  ? -13.129 -55.502 107.094 1   102.409 ? 706  ILE   A N    1 ? 
ATOM   151  C CA   . ILE   A 1 12  ? -13.555 -54.127 107.253 1   101.591 ? 706  ILE   A CA   1 ? 
ATOM   152  C C    . ILE   A 1 12  ? -14.638 -54.119 108.316 1   103.107 ? 706  ILE   A C    1 ? 
ATOM   153  O O    . ILE   A 1 12  ? -15.565 -54.922 108.251 1   108.749 ? 706  ILE   A O    1 ? 
ATOM   154  C CB   . ILE   A 1 12  ? -14.067 -53.535 105.93  1   104.043 ? 706  ILE   A CB   1 ? 
ATOM   155  C CG1  . ILE   A 1 12  ? -13.131 -53.866 104.775 1   103.721 ? 706  ILE   A CG1  1 ? 
ATOM   156  C CG2  . ILE   A 1 12  ? -14.291 -52.026 106.063 1   111.625 ? 706  ILE   A CG2  1 ? 
ATOM   157  C CD1  . ILE   A 1 12  ? -11.82  -53.101 104.791 1   100.289 ? 706  ILE   A CD1  1 ? 
ATOM   158  H H    . ILE   A 1 12  ? -13.652 -56.065 106.601 1   101.26  ? 706  ILE   A H    1 c 
ATOM   159  H HA   . ILE   A 1 12  ? -12.799 -53.595 107.561 1   102.619 ? 706  ILE   A HA   1 c 
ATOM   160  H HB   . ILE   A 1 12  ? -14.932 -53.949 105.735 1   104.877 ? 706  ILE   A HB   1 c 
ATOM   161  H HG12 . ILE   A 1 12  ? -12.935 -54.824 104.79  1   102.981 ? 706  ILE   A HG12 1 c 
ATOM   162  H HG13 . ILE   A 1 12  ? -13.594 -53.671 103.935 1   102.993 ? 706  ILE   A HG13 1 c 
ATOM   163  H HG21 . ILE   A 1 12  ? -14.467 -51.644 105.186 1   109.315 ? 706  ILE   A HG21 1 c 
ATOM   164  H HG22 . ILE   A 1 12  ? -13.499 -51.61  106.442 1   109.244 ? 706  ILE   A HG22 1 c 
ATOM   165  H HG23 . ILE   A 1 12  ? -15.052 -51.86  106.645 1   109.291 ? 706  ILE   A HG23 1 c 
ATOM   166  H HD11 . ILE   A 1 12  ? -11.982 -52.163 104.573 1   101.341 ? 706  ILE   A HD11 1 c 
ATOM   167  H HD12 . ILE   A 1 12  ? -11.215 -53.486 104.13  1   101.305 ? 706  ILE   A HD12 1 c 
ATOM   168  H HD13 . ILE   A 1 12  ? -11.413 -53.161 105.676 1   101.31  ? 706  ILE   A HD13 1 c 
ATOM   169  N N    . LEU   A 1 13  ? -14.509 -53.199 109.279 1   123.744 ? 707  LEU   A N    1 ? 
ATOM   170  C CA   . LEU   A 1 13  ? -15.417 -53.133 110.41  1   127.841 ? 707  LEU   A CA   1 ? 
ATOM   171  C C    . LEU   A 1 13  ? -16.181 -51.81  110.39  1   119.466 ? 707  LEU   A C    1 ? 
ATOM   172  O O    . LEU   A 1 13  ? -15.624 -50.76  110.061 1   112.611 ? 707  LEU   A O    1 ? 
ATOM   173  C CB   . LEU   A 1 13  ? -14.63  -53.306 111.712 1   128.347 ? 707  LEU   A CB   1 ? 
ATOM   174  C CG   . LEU   A 1 13  ? -13.635 -54.475 111.771 1   116.767 ? 707  LEU   A CG   1 ? 
ATOM   175  C CD1  . LEU   A 1 13  ? -13.054 -54.578 113.172 1   115.642 ? 707  LEU   A CD1  1 ? 
ATOM   176  C CD2  . LEU   A 1 13  ? -14.236 -55.822 111.37  1   116.013 ? 707  LEU   A CD2  1 ? 
ATOM   177  H H    . LEU   A 1 13  ? -13.831 -52.589 109.226 1   119.043 ? 707  LEU   A H    1 c 
ATOM   178  H HA   . LEU   A 1 13  ? -16.07  -53.873 110.331 1   125.046 ? 707  LEU   A HA   1 c 
ATOM   179  H HB2  . LEU   A 1 13  ? -14.135 -52.472 111.882 1   125.471 ? 707  LEU   A HB2  1 c 
ATOM   180  H HB3  . LEU   A 1 13  ? -15.277 -53.413 112.447 1   125.477 ? 707  LEU   A HB3  1 c 
ATOM   181  H HG   . LEU   A 1 13  ? -12.89  -54.277 111.147 1   118.482 ? 707  LEU   A HG   1 c 
ATOM   182  H HD11 . LEU   A 1 13  ? -12.488 -53.81  113.346 1   115.956 ? 707  LEU   A HD11 1 c 
ATOM   183  H HD12 . LEU   A 1 13  ? -12.527 -55.391 113.249 1   115.807 ? 707  LEU   A HD12 1 c 
ATOM   184  H HD13 . LEU   A 1 13  ? -13.776 -54.601 113.822 1   115.996 ? 707  LEU   A HD13 1 c 
ATOM   185  H HD21 . LEU   A 1 13  ? -14.499 -55.798 110.437 1   116.169 ? 707  LEU   A HD21 1 c 
ATOM   186  H HD22 . LEU   A 1 13  ? -15.016 -56.006 111.921 1   116.218 ? 707  LEU   A HD22 1 c 
ATOM   187  H HD23 . LEU   A 1 13  ? -13.576 -56.524 111.501 1   116.216 ? 707  LEU   A HD23 1 c 
ATOM   188  N N    . LYS   A 1 14  ? -17.472 -51.894 110.743 1   108.406 ? 708  LYS   A N    1 ? 
ATOM   189  C CA   . LYS   A 1 14  ? -18.293 -50.722 110.99  1   110.587 ? 708  LYS   A CA   1 ? 
ATOM   190  C C    . LYS   A 1 14  ? -17.872 -50.08  112.309 1   104.294 ? 708  LYS   A C    1 ? 
ATOM   191  O O    . LYS   A 1 14  ? -17.535 -50.799 113.242 1   106.554 ? 708  LYS   A O    1 ? 
ATOM   192  C CB   . LYS   A 1 14  ? -19.768 -51.131 111.046 1   120.52  ? 708  LYS   A CB   1 ? 
ATOM   193  C CG   . LYS   A 1 14  ? -20.306 -51.78  109.796 1   134.702 ? 708  LYS   A CG   1 ? 
ATOM   194  C CD   . LYS   A 1 14  ? -21.715 -51.296 109.466 1   148.18  ? 708  LYS   A CD   1 ? 
ATOM   195  C CE   . LYS   A 1 14  ? -22.658 -52.39  109.121 1   150.111 ? 708  LYS   A CE   1 ? 
ATOM   196  N NZ   . LYS   A 1 14  ? -23.314 -52.913 110.323 1   156.566 ? 708  LYS   A NZ   1 ? 
ATOM   197  H H    . LYS   A 1 14  ? -17.853 -52.72  110.837 1   111.833 ? 708  LYS   A H    1 c 
ATOM   198  H HA   . LYS   A 1 14  ? -18.154 -50.075 110.251 1   110.711 ? 708  LYS   A HA   1 c 
ATOM   199  H HB2  . LYS   A 1 14  ? -19.89  -51.755 111.793 1   121.342 ? 708  LYS   A HB2  1 c 
ATOM   200  H HB3  . LYS   A 1 14  ? -20.303 -50.332 111.238 1   121.597 ? 708  LYS   A HB3  1 c 
ATOM   201  H HG2  . LYS   A 1 14  ? -19.707 -51.572 109.046 1   134.03  ? 708  LYS   A HG2  1 c 
ATOM   202  H HG3  . LYS   A 1 14  ? -20.315 -52.754 109.923 1   134.305 ? 708  LYS   A HG3  1 c 
ATOM   203  H HD2  . LYS   A 1 14  ? -22.073 -50.799 110.233 1   145.21  ? 708  LYS   A HD2  1 c 
ATOM   204  H HD3  . LYS   A 1 14  ? -21.663 -50.672 108.709 1   145.407 ? 708  LYS   A HD3  1 c 
ATOM   205  H HE2  . LYS   A 1 14  ? -23.338 -52.052 108.511 1   151.115 ? 708  LYS   A HE2  1 c 
ATOM   206  H HE3  . LYS   A 1 14  ? -22.182 -53.113 108.675 1   150.936 ? 708  LYS   A HE3  1 c 
ATOM   207  H HZ1  . LYS   A 1 14  ? -23.837 -52.271 110.691 1   154.474 ? 708  LYS   A HZ1  1 c 
ATOM   208  H HZ2  . LYS   A 1 14  ? -22.689 -53.171 110.927 1   154.497 ? 708  LYS   A HZ2  1 c 
ATOM   209  H HZ3  . LYS   A 1 14  ? -23.828 -53.625 110.104 1   154.525 ? 708  LYS   A HZ3  1 c 
ATOM   210  N N    . GLU   A 1 15  ? -17.915 -48.74  112.383 1   103.398 ? 709  GLU   A N    1 ? 
ATOM   211  C CA   . GLU   A 1 15  ? -17.556 -47.993 113.583 1   112.984 ? 709  GLU   A CA   1 ? 
ATOM   212  C C    . GLU   A 1 15  ? -18.483 -48.356 114.737 1   110.481 ? 709  GLU   A C    1 ? 
ATOM   213  O O    . GLU   A 1 15  ? -18.08  -48.336 115.897 1   119.143 ? 709  GLU   A O    1 ? 
ATOM   214  C CB   . GLU   A 1 15  ? -17.646 -46.482 113.361 1   126.498 ? 709  GLU   A CB   1 ? 
ATOM   215  C CG   . GLU   A 1 15  ? -17.338 -45.668 114.618 1   138.526 ? 709  GLU   A CG   1 ? 
ATOM   216  C CD   . GLU   A 1 15  ? -16.177 -44.686 114.487 1   148.198 ? 709  GLU   A CD   1 ? 
ATOM   217  O OE1  . GLU   A 1 15  ? -16.176 -43.844 113.562 1   158.92  ? 709  GLU   A OE1  1 ? 
ATOM   218  O OE2  . GLU   A 1 15  ? -15.241 -44.759 115.316 1   128.668 ? 709  GLU   A OE2  1 ? 
ATOM   219  H H    . GLU   A 1 15  ? -18.184 -48.271 111.647 1   105.904 ? 709  GLU   A H    1 c 
ATOM   220  H HA   . GLU   A 1 15  ? -16.628 -48.229 113.832 1   113.003 ? 709  GLU   A HA   1 c 
ATOM   221  H HB2  . GLU   A 1 15  ? -17.02  -46.231 112.65  1   126.106 ? 709  GLU   A HB2  1 c 
ATOM   222  H HB3  . GLU   A 1 15  ? -18.55  -46.262 113.054 1   125.899 ? 709  GLU   A HB3  1 c 
ATOM   223  H HG2  . GLU   A 1 15  ? -18.14  -45.165 114.873 1   137.708 ? 709  GLU   A HG2  1 c 
ATOM   224  H HG3  . GLU   A 1 15  ? -17.132 -46.279 115.354 1   137.301 ? 709  GLU   A HG3  1 c 
ATOM   225  N N    . THR   A 1 16  ? -19.735 -48.654 114.394 1   113.117 ? 710  THR   A N    1 ? 
ATOM   226  C CA   . THR   A 1 16  ? -20.746 -49.021 115.368 1   119.795 ? 710  THR   A CA   1 ? 
ATOM   227  C C    . THR   A 1 16  ? -20.396 -50.345 116.041 1   118.199 ? 710  THR   A C    1 ? 
ATOM   228  O O    . THR   A 1 16  ? -20.782 -50.551 117.186 1   141.841 ? 710  THR   A O    1 ? 
ATOM   229  C CB   . THR   A 1 16  ? -22.114 -49.073 114.684 1   128.355 ? 710  THR   A CB   1 ? 
ATOM   230  O OG1  . THR   A 1 16  ? -22.051 -49.866 113.501 1   107.735 ? 710  THR   A OG1  1 ? 
ATOM   231  C CG2  . THR   A 1 16  ? -22.601 -47.688 114.299 1   129.665 ? 710  THR   A CG2  1 ? 
ATOM   232  H H    . THR   A 1 16  ? -19.977 -48.614 113.514 1   113.979 ? 710  THR   A H    1 c 
ATOM   233  H HA   . THR   A 1 16  ? -20.773 -48.321 116.056 1   119.626 ? 710  THR   A HA   1 c 
ATOM   234  H HB   . THR   A 1 16  ? -22.769 -49.474 115.304 1   122.691 ? 710  THR   A HB   1 c 
ATOM   235  H HG1  . THR   A 1 16  ? -21.476 -49.491 112.954 0   106.68  ? 710  THR   A HG1  1 c 
ATOM   236  H HG21 . THR   A 1 16  ? -23.465 -47.757 113.859 1   129.254 ? 710  THR   A HG21 1 c 
ATOM   237  H HG22 . THR   A 1 16  ? -21.962 -47.275 113.693 1   129.185 ? 710  THR   A HG22 1 c 
ATOM   238  H HG23 . THR   A 1 16  ? -22.688 -47.141 115.098 1   129.254 ? 710  THR   A HG23 1 c 
ATOM   239  N N    . GLU   A 1 17  ? -19.672 -51.228 115.338 1   117.139 ? 711  GLU   A N    1 ? 
ATOM   240  C CA   . GLU   A 1 17  ? -19.344 -52.56  115.832 1   118.42  ? 711  GLU   A CA   1 ? 
ATOM   241  C C    . GLU   A 1 17  ? -18.501 -52.516 117.111 1   110.134 ? 711  GLU   A C    1 ? 
ATOM   242  O O    . GLU   A 1 17  ? -18.607 -53.413 117.94  1   91.336  ? 711  GLU   A O    1 ? 
ATOM   243  C CB   . GLU   A 1 17  ? -18.572 -53.37  114.793 1   117.527 ? 711  GLU   A CB   1 ? 
ATOM   244  C CG   . GLU   A 1 17  ? -19.452 -54.233 113.898 1   116.854 ? 711  GLU   A CG   1 ? 
ATOM   245  C CD   . GLU   A 1 17  ? -18.643 -55.013 112.873 1   124.823 ? 711  GLU   A CD   1 ? 
ATOM   246  O OE1  . GLU   A 1 17  ? -17.408 -54.966 112.947 1   133.213 ? 711  GLU   A OE1  1 ? 
ATOM   247  O OE2  . GLU   A 1 17  ? -19.211 -55.673 111.997 1   143.031 ? 711  GLU   A OE2  1 ? 
ATOM   248  H H    . GLU   A 1 17  ? -19.384 -50.994 114.504 1   117.541 ? 711  GLU   A H    1 c 
ATOM   249  H HA   . GLU   A 1 17  ? -20.193 -53.032 116.033 1   116.456 ? 711  GLU   A HA   1 c 
ATOM   250  H HB2  . GLU   A 1 17  ? -18.052 -52.759 114.236 1   117.568 ? 711  GLU   A HB2  1 c 
ATOM   251  H HB3  . GLU   A 1 17  ? -17.941 -53.955 115.26  1   117.583 ? 711  GLU   A HB3  1 c 
ATOM   252  H HG2  . GLU   A 1 17  ? -19.956 -54.867 114.452 1   118.783 ? 711  GLU   A HG2  1 c 
ATOM   253  H HG3  . GLU   A 1 17  ? -20.095 -53.662 113.426 1   118.783 ? 711  GLU   A HG3  1 c 
ATOM   254  N N    . PHE   A 1 18  ? -17.649 -51.497 117.267 1   97.091  ? 712  PHE   A N    1 ? 
ATOM   255  C CA   . PHE   A 1 18  ? -16.748 -51.435 118.404 1   100.338 ? 712  PHE   A CA   1 ? 
ATOM   256  C C    . PHE   A 1 18  ? -16.927 -50.099 119.119 1   106.138 ? 712  PHE   A C    1 ? 
ATOM   257  O O    . PHE   A 1 18  ? -17.367 -49.126 118.519 1   118.723 ? 712  PHE   A O    1 ? 
ATOM   258  C CB   . PHE   A 1 18  ? -15.307 -51.675 117.932 1   117.866 ? 712  PHE   A CB   1 ? 
ATOM   259  C CG   . PHE   A 1 18  ? -14.865 -50.723 116.838 1   119.528 ? 712  PHE   A CG   1 ? 
ATOM   260  C CD1  . PHE   A 1 18  ? -14.988 -51.068 115.497 1   115.117 ? 712  PHE   A CD1  1 ? 
ATOM   261  C CD2  . PHE   A 1 18  ? -14.384 -49.466 117.17  1   125.202 ? 712  PHE   A CD2  1 ? 
ATOM   262  C CE1  . PHE   A 1 18  ? -14.608 -50.177 114.513 1   122.292 ? 712  PHE   A CE1  1 ? 
ATOM   263  C CE2  . PHE   A 1 18  ? -14.005 -48.578 116.184 1   128.525 ? 712  PHE   A CE2  1 ? 
ATOM   264  C CZ   . PHE   A 1 18  ? -14.115 -48.937 114.858 1   132.252 ? 712  PHE   A CZ   1 ? 
ATOM   265  H H    . PHE   A 1 18  ? -17.628 -50.823 116.65  1   101.252 ? 712  PHE   A H    1 c 
ATOM   266  H HA   . PHE   A 1 18  ? -16.992 -52.159 119.036 1   103.783 ? 712  PHE   A HA   1 c 
ATOM   267  H HB2  . PHE   A 1 18  ? -14.704 -51.578 118.703 1   114.002 ? 712  PHE   A HB2  1 c 
ATOM   268  H HB3  . PHE   A 1 18  ? -15.234 -52.598 117.602 1   114.002 ? 712  PHE   A HB3  1 c 
ATOM   269  H HD1  . PHE   A 1 18  ? -15.326 -51.917 115.261 1   117.985 ? 712  PHE   A HD1  1 c 
ATOM   270  H HD2  . PHE   A 1 18  ? -14.308 -49.22  118.078 1   124.582 ? 712  PHE   A HD2  1 c 
ATOM   271  H HE1  . PHE   A 1 18  ? -14.68  -50.421 113.604 1   122.82  ? 712  PHE   A HE1  1 c 
ATOM   272  H HE2  . PHE   A 1 18  ? -13.665 -47.729 116.418 1   128.4   ? 712  PHE   A HE2  1 c 
ATOM   273  H HZ   . PHE   A 1 18  ? -13.853 -48.335 114.184 1   128.945 ? 712  PHE   A HZ   1 c 
ATOM   274  N N    . LYS   A 1 19  ? -16.552 -50.062 120.405 1   123.604 ? 713  LYS   A N    1 ? 
ATOM   275  C CA   . LYS   A 1 19  ? -16.577 -48.845 121.201 1   126.238 ? 713  LYS   A CA   1 ? 
ATOM   276  C C    . LYS   A 1 19  ? -15.202 -48.596 121.833 1   127.345 ? 713  LYS   A C    1 ? 
ATOM   277  O O    . LYS   A 1 19  ? -14.519 -49.54  122.223 1   133.671 ? 713  LYS   A O    1 ? 
ATOM   278  C CB   . LYS   A 1 19  ? -17.665 -48.984 122.268 1   131.069 ? 713  LYS   A CB   1 ? 
ATOM   279  C CG   . LYS   A 1 19  ? -17.188 -49.503 123.616 1   137.412 ? 713  LYS   A CG   1 ? 
ATOM   280  C CD   . LYS   A 1 19  ? -18.187 -49.249 124.732 1   152.205 ? 713  LYS   A CD   1 ? 
ATOM   281  C CE   . LYS   A 1 19  ? -19.437 -50.056 124.584 1   161.906 ? 713  LYS   A CE   1 ? 
ATOM   282  N NZ   . LYS   A 1 19  ? -20.5   -49.554 125.457 1   170.207 ? 713  LYS   A NZ   1 ? 
ATOM   283  H H    . LYS   A 1 19  ? -16.265 -50.834 120.802 1   119.474 ? 713  LYS   A H    1 c 
ATOM   284  H HA   . LYS   A 1 19  ? -16.799 -48.082 120.609 1   126.596 ? 713  LYS   A HA   1 c 
ATOM   285  H HB2  . LYS   A 1 19  ? -18.082 -48.107 122.404 1   131.649 ? 713  LYS   A HB2  1 c 
ATOM   286  H HB3  . LYS   A 1 19  ? -18.357 -49.592 121.93  1   131.69  ? 713  LYS   A HB3  1 c 
ATOM   287  H HG2  . LYS   A 1 19  ? -17.023 -50.468 123.543 1   139.116 ? 713  LYS   A HG2  1 c 
ATOM   288  H HG3  . LYS   A 1 19  ? -16.342 -49.065 123.846 1   139.04  ? 713  LYS   A HG3  1 c 
ATOM   289  H HD2  . LYS   A 1 19  ? -17.767 -49.466 125.593 1   150.845 ? 713  LYS   A HD2  1 c 
ATOM   290  H HD3  . LYS   A 1 19  ? -18.421 -48.295 124.742 1   150.819 ? 713  LYS   A HD3  1 c 
ATOM   291  H HE2  . LYS   A 1 19  ? -19.749 -50.026 123.662 1   161.146 ? 713  LYS   A HE2  1 c 
ATOM   292  H HE3  . LYS   A 1 19  ? -19.253 -50.985 124.812 1   161.456 ? 713  LYS   A HE3  1 c 
ATOM   293  H HZ1  . LYS   A 1 19  ? -20.707 -48.702 125.228 1   167.487 ? 713  LYS   A HZ1  1 c 
ATOM   294  H HZ2  . LYS   A 1 19  ? -20.222 -49.571 126.319 1   167.579 ? 713  LYS   A HZ2  1 c 
ATOM   295  H HZ3  . LYS   A 1 19  ? -21.238 -50.072 125.371 1   167.579 ? 713  LYS   A HZ3  1 c 
ATOM   296  N N    . LYS   A 1 20  ? -14.826 -47.316 121.958 1   126.378 ? 714  LYS   A N    1 ? 
ATOM   297  C CA   . LYS   A 1 20  ? -13.591 -46.921 122.612 1   121.994 ? 714  LYS   A CA   1 ? 
ATOM   298  C C    . LYS   A 1 20  ? -13.9   -46.609 124.074 1   124.735 ? 714  LYS   A C    1 ? 
ATOM   299  O O    . LYS   A 1 20  ? -14.814 -45.846 124.358 1   131.022 ? 714  LYS   A O    1 ? 
ATOM   300  C CB   . LYS   A 1 20  ? -12.95  -45.707 121.927 1   124.113 ? 714  LYS   A CB   1 ? 
ATOM   301  C CG   . LYS   A 1 20  ? -13.093 -45.647 120.414 1   127.567 ? 714  LYS   A CG   1 ? 
ATOM   302  C CD   . LYS   A 1 20  ? -11.83  -45.068 119.79  1   128.355 ? 714  LYS   A CD   1 ? 
ATOM   303  C CE   . LYS   A 1 20  ? -12.025 -43.903 118.888 1   117.733 ? 714  LYS   A CE   1 ? 
ATOM   304  N NZ   . LYS   A 1 20  ? -12.841 -44.27  117.728 1   128.09  ? 714  LYS   A NZ   1 ? 
ATOM   305  H H    . LYS   A 1 20  ? -15.371 -46.662 121.625 1   125.624 ? 714  LYS   A H    1 c 
ATOM   306  H HA   . LYS   A 1 20  ? -12.955 -47.679 122.573 1   123.998 ? 714  LYS   A HA   1 c 
ATOM   307  H HB2  . LYS   A 1 20  ? -13.346 -44.893 122.304 1   124.452 ? 714  LYS   A HB2  1 c 
ATOM   308  H HB3  . LYS   A 1 20  ? -11.995 -45.701 122.15  1   124.449 ? 714  LYS   A HB3  1 c 
ATOM   309  H HG2  . LYS   A 1 20  ? -13.247 -46.552 120.066 1   126.905 ? 714  LYS   A HG2  1 c 
ATOM   310  H HG3  . LYS   A 1 20  ? -13.865 -45.084 120.185 1   126.873 ? 714  LYS   A HG3  1 c 
ATOM   311  H HD2  . LYS   A 1 20  ? -11.226 -44.8   120.51  1   125.696 ? 714  LYS   A HD2  1 c 
ATOM   312  H HD3  . LYS   A 1 20  ? -11.38  -45.782 119.287 1   125.623 ? 714  LYS   A HD3  1 c 
ATOM   313  H HE2  . LYS   A 1 20  ? -12.464 -43.182 119.373 1   122.545 ? 714  LYS   A HE2  1 c 
ATOM   314  H HE3  . LYS   A 1 20  ? -11.158 -43.585 118.582 1   122.734 ? 714  LYS   A HE3  1 c 
ATOM   315  H HZ1  . LYS   A 1 20  ? -13.706 -44.373 117.976 1   124.84  ? 714  LYS   A HZ1  1 c 
ATOM   316  H HZ2  . LYS   A 1 20  ? -12.539 -45.046 117.369 1   124.839 ? 714  LYS   A HZ2  1 c 
ATOM   317  H HZ3  . LYS   A 1 20  ? -12.79  -43.616 117.103 1   124.819 ? 714  LYS   A HZ3  1 c 
ATOM   318  N N    . ILE   A 1 21  ? -13.135 -47.201 124.997 1   143.997 ? 715  ILE   A N    1 ? 
ATOM   319  C CA   . ILE   A 1 21  ? -13.389 -47.048 126.423 1   137.527 ? 715  ILE   A CA   1 ? 
ATOM   320  C C    . ILE   A 1 21  ? -12.418 -46.067 127.08  1   125.892 ? 715  ILE   A C    1 ? 
ATOM   321  O O    . ILE   A 1 21  ? -12.818 -45.352 127.99  1   127.105 ? 715  ILE   A O    1 ? 
ATOM   322  C CB   . ILE   A 1 21  ? -13.329 -48.407 127.134 1   133.193 ? 715  ILE   A CB   1 ? 
ATOM   323  C CG1  . ILE   A 1 21  ? -14.518 -49.268 126.751 1   123.743 ? 715  ILE   A CG1  1 ? 
ATOM   324  C CG2  . ILE   A 1 21  ? -13.221 -48.219 128.647 1   130.072 ? 715  ILE   A CG2  1 ? 
ATOM   325  C CD1  . ILE   A 1 21  ? -14.271 -50.748 126.932 1   129.24  ? 715  ILE   A CD1  1 ? 
ATOM   326  H H    . ILE   A 1 21  ? -12.434 -47.723 124.73  1   137.319 ? 715  ILE   A H    1 c 
ATOM   327  H HA   . ILE   A 1 21  ? -14.293 -46.696 126.534 1   135.548 ? 715  ILE   A HA   1 c 
ATOM   328  H HB   . ILE   A 1 21  ? -12.52  -48.866 126.83  1   131.581 ? 715  ILE   A HB   1 c 
ATOM   329  H HG12 . ILE   A 1 21  ? -15.286 -49.007 127.299 1   127.146 ? 715  ILE   A HG12 1 c 
ATOM   330  H HG13 . ILE   A 1 21  ? -14.745 -49.098 125.814 1   127.247 ? 715  ILE   A HG13 1 c 
ATOM   331  H HG21 . ILE   A 1 21  ? -13.371 -49.066 129.089 1   131.177 ? 715  ILE   A HG21 1 c 
ATOM   332  H HG22 . ILE   A 1 21  ? -13.888 -47.578 128.946 1   130.992 ? 715  ILE   A HG22 1 c 
ATOM   333  H HG23 . ILE   A 1 21  ? -12.334 -47.893 128.875 1   131.068 ? 715  ILE   A HG23 1 c 
ATOM   334  H HD11 . ILE   A 1 21  ? -13.525 -51.025 126.367 1   127.641 ? 715  ILE   A HD11 1 c 
ATOM   335  H HD12 . ILE   A 1 21  ? -15.071 -51.245 126.676 1   127.642 ? 715  ILE   A HD12 1 c 
ATOM   336  H HD13 . ILE   A 1 21  ? -14.058 -50.937 127.863 1   127.822 ? 715  ILE   A HD13 1 c 
ATOM   337  N N    . LYS   A 1 22  ? -11.14  -46.092 126.696 1   123.927 ? 716  LYS   A N    1 ? 
ATOM   338  C CA   . LYS   A 1 22  ? -10.115 -45.349 127.414 1   126.09  ? 716  LYS   A CA   1 ? 
ATOM   339  C C    . LYS   A 1 22  ? -8.921  -45.154 126.489 1   114.751 ? 716  LYS   A C    1 ? 
ATOM   340  O O    . LYS   A 1 22  ? -8.779  -45.881 125.52  1   136.927 ? 716  LYS   A O    1 ? 
ATOM   341  C CB   . LYS   A 1 22  ? -9.692  -46.131 128.665 1   150.277 ? 716  LYS   A CB   1 ? 
ATOM   342  C CG   . LYS   A 1 22  ? -8.934  -45.355 129.72  1   160.883 ? 716  LYS   A CG   1 ? 
ATOM   343  C CD   . LYS   A 1 22  ? -8.507  -46.216 130.902 1   156.265 ? 716  LYS   A CD   1 ? 
ATOM   344  C CE   . LYS   A 1 22  ? -7.394  -45.566 131.652 1   154.685 ? 716  LYS   A CE   1 ? 
ATOM   345  N NZ   . LYS   A 1 22  ? -6.837  -46.416 132.71  1   154.596 ? 716  LYS   A NZ   1 ? 
ATOM   346  H H    . LYS   A 1 22  ? -10.896 -46.591 125.97  1   125.1   ? 716  LYS   A H    1 c 
ATOM   347  H HA   . LYS   A 1 22  ? -10.477 -44.463 127.67  1   127.376 ? 716  LYS   A HA   1 c 
ATOM   348  H HB2  . LYS   A 1 22  ? -10.497 -46.503 129.083 1   146.459 ? 716  LYS   A HB2  1 c 
ATOM   349  H HB3  . LYS   A 1 22  ? -9.133  -46.886 128.383 1   146.519 ? 716  LYS   A HB3  1 c 
ATOM   350  H HG2  . LYS   A 1 22  ? -8.137  -44.959 129.308 1   156.462 ? 716  LYS   A HG2  1 c 
ATOM   351  H HG3  . LYS   A 1 22  ? -9.505  -44.624 130.044 1   157.167 ? 716  LYS   A HG3  1 c 
ATOM   352  H HD2  . LYS   A 1 22  ? -9.272  -46.346 131.506 1   156.899 ? 716  LYS   A HD2  1 c 
ATOM   353  H HD3  . LYS   A 1 22  ? -8.212  -47.096 130.578 1   156.802 ? 716  LYS   A HD3  1 c 
ATOM   354  H HE2  . LYS   A 1 22  ? -6.678  -45.34  131.029 1   155.035 ? 716  LYS   A HE2  1 c 
ATOM   355  H HE3  . LYS   A 1 22  ? -7.716  -44.738 132.05  1   155.028 ? 716  LYS   A HE3  1 c 
ATOM   356  H HZ1  . LYS   A 1 22  ? -6.679  -47.248 132.387 1   154.647 ? 716  LYS   A HZ1  1 c 
ATOM   357  H HZ2  . LYS   A 1 22  ? -7.425  -46.471 133.398 1   154.629 ? 716  LYS   A HZ2  1 c 
ATOM   358  H HZ3  . LYS   A 1 22  ? -6.06   -46.061 133.011 1   154.629 ? 716  LYS   A HZ3  1 c 
ATOM   359  N N    . VAL   A 1 23  ? -8.07   -44.175 126.791 1   112.631 ? 717  VAL   A N    1 ? 
ATOM   360  C CA   . VAL   A 1 23  ? -6.889  -43.914 125.987 1   120.774 ? 717  VAL   A CA   1 ? 
ATOM   361  C C    . VAL   A 1 23  ? -5.694  -44.587 126.65  1   116.594 ? 717  VAL   A C    1 ? 
ATOM   362  O O    . VAL   A 1 23  ? -5.296  -44.228 127.749 1   134.747 ? 717  VAL   A O    1 ? 
ATOM   363  C CB   . VAL   A 1 23  ? -6.619  -42.41  125.781 1   130.761 ? 717  VAL   A CB   1 ? 
ATOM   364  C CG1  . VAL   A 1 23  ? -5.141  -42.097 125.568 1   143.383 ? 717  VAL   A CG1  1 ? 
ATOM   365  C CG2  . VAL   A 1 23  ? -7.432  -41.833 124.637 1   124.525 ? 717  VAL   A CG2  1 ? 
ATOM   366  H H    . VAL   A 1 23  ? -8.235  -43.644 127.516 1   115.699 ? 717  VAL   A H    1 c 
ATOM   367  H HA   . VAL   A 1 23  ? -7.021  -44.319 125.109 1   120.277 ? 717  VAL   A HA   1 c 
ATOM   368  H HB   . VAL   A 1 23  ? -6.901  -41.951 126.607 1   129.791 ? 717  VAL   A HB   1 c 
ATOM   369  H HG11 . VAL   A 1 23  ? -4.76   -42.732 124.938 1   139.327 ? 717  VAL   A HG11 1 c 
ATOM   370  H HG12 . VAL   A 1 23  ? -4.667  -42.156 126.415 1   139.301 ? 717  VAL   A HG12 1 c 
ATOM   371  H HG13 . VAL   A 1 23  ? -5.048  -41.197 125.212 1   139.28  ? 717  VAL   A HG13 1 c 
ATOM   372  H HG21 . VAL   A 1 23  ? -7.293  -40.872 124.591 1   126.431 ? 717  VAL   A HG21 1 c 
ATOM   373  H HG22 . VAL   A 1 23  ? -8.375  -42.015 124.784 1   126.366 ? 717  VAL   A HG22 1 c 
ATOM   374  H HG23 . VAL   A 1 23  ? -7.15   -42.241 123.801 1   126.394 ? 717  VAL   A HG23 1 c 
ATOM   375  N N    . LEU   A 1 24  ? -5.093  -45.547 125.951 1   128.021 ? 718  LEU   A N    1 ? 
ATOM   376  C CA   . LEU   A 1 24  ? -3.845  -46.15  126.397 1   133.254 ? 718  LEU   A CA   1 ? 
ATOM   377  C C    . LEU   A 1 24  ? -2.657  -45.229 126.099 1   130.43  ? 718  LEU   A C    1 ? 
ATOM   378  O O    . LEU   A 1 24  ? -1.754  -45.097 126.916 1   140.946 ? 718  LEU   A O    1 ? 
ATOM   379  C CB   . LEU   A 1 24  ? -3.702  -47.512 125.721 1   138.44  ? 718  LEU   A CB   1 ? 
ATOM   380  C CG   . LEU   A 1 24  ? -4.922  -48.428 125.862 1   126.308 ? 718  LEU   A CG   1 ? 
ATOM   381  C CD1  . LEU   A 1 24  ? -4.736  -49.728 125.112 1   132.149 ? 718  LEU   A CD1  1 ? 
ATOM   382  C CD2  . LEU   A 1 24  ? -5.205  -48.683 127.323 1   120.781 ? 718  LEU   A CD2  1 ? 
ATOM   383  H H    . LEU   A 1 24  ? -5.46   -45.824 125.162 1   126.327 ? 718  LEU   A H    1 c 
ATOM   384  H HA   . LEU   A 1 24  ? -3.896  -46.282 127.377 1   132.479 ? 718  LEU   A HA   1 c 
ATOM   385  H HB2  . LEU   A 1 24  ? -3.53   -47.365 124.762 1   134.398 ? 718  LEU   A HB2  1 c 
ATOM   386  H HB3  . LEU   A 1 24  ? -2.92   -47.969 126.108 1   134.333 ? 718  LEU   A HB3  1 c 
ATOM   387  H HG   . LEU   A 1 24  ? -5.706  -47.964 125.475 1   128.135 ? 718  LEU   A HG   1 c 
ATOM   388  H HD11 . LEU   A 1 24  ? -4.562  -49.541 124.174 1   130.409 ? 718  LEU   A HD11 1 c 
ATOM   389  H HD12 . LEU   A 1 24  ? -5.542  -50.267 125.189 1   130.367 ? 718  LEU   A HD12 1 c 
ATOM   390  H HD13 . LEU   A 1 24  ? -3.986  -50.216 125.488 1   130.52  ? 718  LEU   A HD13 1 c 
ATOM   391  H HD21 . LEU   A 1 24  ? -5.711  -47.939 127.691 1   122.525 ? 718  LEU   A HD21 1 c 
ATOM   392  H HD22 . LEU   A 1 24  ? -4.365  -48.772 127.806 1   122.615 ? 718  LEU   A HD22 1 c 
ATOM   393  H HD23 . LEU   A 1 24  ? -5.718  -49.502 127.419 1   122.617 ? 718  LEU   A HD23 1 c 
ATOM   394  N N    . GLY   A 1 25  ? -2.629  -44.605 124.921 1   128.17  ? 719  GLY   A N    1 ? 
ATOM   395  C CA   . GLY   A 1 25  ? -1.475  -43.814 124.523 1   129.284 ? 719  GLY   A CA   1 ? 
ATOM   396  C C    . GLY   A 1 25  ? -1.858  -42.802 123.449 1   139.361 ? 719  GLY   A C    1 ? 
ATOM   397  O O    . GLY   A 1 25  ? -2.898  -42.963 122.81  1   144.374 ? 719  GLY   A O    1 ? 
ATOM   398  H H    . GLY   A 1 25  ? -3.338  -44.676 124.35  1   129.043 ? 719  GLY   A H    1 c 
ATOM   399  H HA2  . GLY   A 1 25  ? -1.114  -43.34  125.309 1   131.349 ? 719  GLY   A HA2  1 c 
ATOM   400  H HA3  . GLY   A 1 25  ? -0.772  -44.414 124.178 1   131.222 ? 719  GLY   A HA3  1 c 
ATOM   401  N N    . SER   A 1 26  ? -1.011  -41.779 123.27  1   147.337 ? 720  SER   A N    1 ? 
ATOM   402  C CA   . SER   A 1 26  ? -1.281  -40.678 122.352 1   160.758 ? 720  SER   A CA   1 ? 
ATOM   403  C C    . SER   A 1 26  ? 0.046   -40.085 121.861 1   155.366 ? 720  SER   A C    1 ? 
ATOM   404  O O    . SER   A 1 26  ? 1.086   -40.339 122.471 1   126.52  ? 720  SER   A O    1 ? 
ATOM   405  C CB   . SER   A 1 26  ? -2.184  -39.628 122.996 1   157.305 ? 720  SER   A CB   1 ? 
ATOM   406  O OG   . SER   A 1 26  ? -1.45   -38.491 123.423 1   167.566 ? 720  SER   A OG   1 ? 
ATOM   407  H H    . SER   A 1 26  ? -0.23   -41.767 123.745 1   148.05  ? 720  SER   A H    1 c 
ATOM   408  H HA   . SER   A 1 26  ? -1.755  -41.049 121.565 1   156.115 ? 720  SER   A HA   1 c 
ATOM   409  H HB2  . SER   A 1 26  ? -2.862  -39.35  122.351 1   160.584 ? 720  SER   A HB2  1 c 
ATOM   410  H HB3  . SER   A 1 26  ? -2.641  -40.023 123.762 1   160.321 ? 720  SER   A HB3  1 c 
ATOM   411  H HG   . SER   A 1 26  ? -1.96   -37.943 123.798 0   169.03  ? 720  SER   A HG   1 c 
ATOM   412  N N    . GLY   A 1 27  ? 0.003   -39.311 120.756 1   158.697 ? 721  GLY   A N    1 ? 
ATOM   413  C CA   . GLY   A 1 27  ? 1.179   -38.67  120.178 1   150.487 ? 721  GLY   A CA   1 ? 
ATOM   414  C C    . GLY   A 1 27  ? 1.67    -39.441 118.959 1   163.77  ? 721  GLY   A C    1 ? 
ATOM   415  O O    . GLY   A 1 27  ? 1.234   -40.566 118.745 1   173.946 ? 721  GLY   A O    1 ? 
ATOM   416  H H    . GLY   A 1 27  ? -0.802  -39.192 120.341 1   156.323 ? 721  GLY   A H    1 c 
ATOM   417  H HA2  . GLY   A 1 27  ? 0.954   -37.751 119.916 1   155.92  ? 721  GLY   A HA2  1 c 
ATOM   418  H HA3  . GLY   A 1 27  ? 1.895   -38.627 120.854 1   155.23  ? 721  GLY   A HA3  1 c 
ATOM   419  N N    . ALA   A 1 28  ? 2.596   -38.838 118.199 1   184.549 ? 722  ALA   A N    1 ? 
ATOM   420  C CA   . ALA   A 1 28  ? 3.033   -39.358 116.908 1   180.741 ? 722  ALA   A CA   1 ? 
ATOM   421  C C    . ALA   A 1 28  ? 1.849   -39.324 115.927 1   196.833 ? 722  ALA   A C    1 ? 
ATOM   422  O O    . ALA   A 1 28  ? 1.018   -38.41  116.015 1   165.326 ? 722  ALA   A O    1 ? 
ATOM   423  C CB   . ALA   A 1 28  ? 3.668   -40.733 117.088 1   150.449 ? 722  ALA   A CB   1 ? 
ATOM   424  H H    . ALA   A 1 28  ? 2.974   -38.064 118.503 1   178.313 ? 722  ALA   A H    1 c 
ATOM   425  H HA   . ALA   A 1 28  ? 3.729   -38.737 116.557 1   178.21  ? 722  ALA   A HA   1 c 
ATOM   426  H HB1  . ALA   A 1 28  ? 4.213   -40.737 117.893 1   158.963 ? 722  ALA   A HB1  1 c 
ATOM   427  H HB2  . ALA   A 1 28  ? 2.975   -41.41  117.167 1   159.331 ? 722  ALA   A HB2  1 c 
ATOM   428  H HB3  . ALA   A 1 28  ? 4.23    -40.936 116.321 1   159.14  ? 722  ALA   A HB3  1 c 
ATOM   429  N N    . PHE   A 1 29  ? 1.771   -40.31  115.005 1   197.823 ? 723  PHE   A N    1 ? 
ATOM   430  C CA   . PHE   A 1 29  ? 0.757   -40.371 113.954 1   180.599 ? 723  PHE   A CA   1 ? 
ATOM   431  C C    . PHE   A 1 29  ? -0.654  -40.271 114.551 1   176.581 ? 723  PHE   A C    1 ? 
ATOM   432  O O    . PHE   A 1 29  ? -1.466  -39.49  114.049 1   151.841 ? 723  PHE   A O    1 ? 
ATOM   433  C CB   . PHE   A 1 29  ? 0.965   -41.627 113.089 1   144.711 ? 723  PHE   A CB   1 ? 
ATOM   434  H H    . PHE   A 1 29  ? 2.394   -40.978 115.033 1   192.103 ? 723  PHE   A H    1 c 
ATOM   435  H HA   . PHE   A 1 29  ? 0.89    -39.58  113.367 1   175.622 ? 723  PHE   A HA   1 c 
ATOM   436  H HB2  . PHE   A 1 29  ? 1.902   -41.854 113.009 0   152.4   ? 723  PHE   A HB2  1 c 
ATOM   437  H HB3  . PHE   A 1 29  ? 0.052   -42.047 112.888 0   152.4   ? 723  PHE   A HB3  1 c 
ATOM   438  N N    . GLY   A 1 30  ? -0.944  -41.052 115.614 1   166.152 ? 724  GLY   A N    1 ? 
ATOM   439  C CA   . GLY   A 1 30  ? -2.291  -41.155 116.17  1   165.591 ? 724  GLY   A CA   1 ? 
ATOM   440  C C    . GLY   A 1 30  ? -2.316  -41.502 117.664 1   151.019 ? 724  GLY   A C    1 ? 
ATOM   441  O O    . GLY   A 1 30  ? -1.303  -41.399 118.348 1   155.996 ? 724  GLY   A O    1 ? 
ATOM   442  H H    . GLY   A 1 30  ? -0.274  -41.538 116.002 1   168.59  ? 724  GLY   A H    1 c 
ATOM   443  H HA2  . GLY   A 1 30  ? -2.762  -40.301 116.03  1   162.397 ? 724  GLY   A HA2  1 c 
ATOM   444  H HA3  . GLY   A 1 30  ? -2.778  -41.848 115.672 1   162.508 ? 724  GLY   A HA3  1 c 
ATOM   445  N N    . THR   A 1 31  ? -3.502  -41.885 118.164 1   138.169 ? 725  THR   A N    1 ? 
ATOM   446  C CA   . THR   A 1 31  ? -3.693  -42.33  119.538 1   131.521 ? 725  THR   A CA   1 ? 
ATOM   447  C C    . THR   A 1 31  ? -4.343  -43.707 119.507 1   136.66  ? 725  THR   A C    1 ? 
ATOM   448  O O    . THR   A 1 31  ? -5.192  -43.957 118.661 1   149.659 ? 725  THR   A O    1 ? 
ATOM   449  C CB   . THR   A 1 31  ? -4.584  -41.365 120.322 1   128.9   ? 725  THR   A CB   1 ? 
ATOM   450  O OG1  . THR   A 1 31  ? -5.858  -41.973 120.533 1   113.456 ? 725  THR   A OG1  1 ? 
ATOM   451  C CG2  . THR   A 1 31  ? -4.719  -40.025 119.629 1   135.592 ? 725  THR   A CG2  1 ? 
ATOM   452  H H    . THR   A 1 31  ? -4.228  -41.877 117.609 1   139.635 ? 725  THR   A H    1 c 
ATOM   453  H HA   . THR   A 1 31  ? -2.82   -42.394 119.981 1   133.64  ? 725  THR   A HA   1 c 
ATOM   454  H HB   . THR   A 1 31  ? -4.165  -41.204 121.201 1   127.469 ? 725  THR   A HB   1 c 
ATOM   455  H HG1  . THR   A 1 31  ? -6.225  -42.162 119.766 0   114.61  ? 725  THR   A HG1  1 c 
ATOM   456  H HG21 . THR   A 1 31  ? -5.21   -39.412 120.202 1   133.765 ? 725  THR   A HG21 1 c 
ATOM   457  H HG22 . THR   A 1 31  ? -5.197  -40.136 118.794 1   134.01  ? 725  THR   A HG22 1 c 
ATOM   458  H HG23 . THR   A 1 31  ? -3.835  -39.661 119.451 1   134.133 ? 725  THR   A HG23 1 c 
ATOM   459  N N    . VAL   A 1 32  ? -3.985  -44.563 120.469 1   147.75  ? 726  VAL   A N    1 ? 
ATOM   460  C CA   . VAL   A 1 32  ? -4.495  -45.925 120.543 1   135.539 ? 726  VAL   A CA   1 ? 
ATOM   461  C C    . VAL   A 1 32  ? -5.376  -46.042 121.782 1   114.156 ? 726  VAL   A C    1 ? 
ATOM   462  O O    . VAL   A 1 32  ? -4.978  -45.616 122.854 1   103.143 ? 726  VAL   A O    1 ? 
ATOM   463  C CB   . VAL   A 1 32  ? -3.383  -46.998 120.529 1   132.834 ? 726  VAL   A CB   1 ? 
ATOM   464  C CG1  . VAL   A 1 32  ? -2.032  -46.455 120.977 1   127.618 ? 726  VAL   A CG1  1 ? 
ATOM   465  C CG2  . VAL   A 1 32  ? -3.756  -48.233 121.34  1   125.722 ? 726  VAL   A CG2  1 ? 
ATOM   466  H H    . VAL   A 1 32  ? -3.418  -44.273 121.125 1   141.868 ? 726  VAL   A H    1 c 
ATOM   467  H HA   . VAL   A 1 32  ? -5.054  -46.071 119.764 1   132.67  ? 726  VAL   A HA   1 c 
ATOM   468  H HB   . VAL   A 1 32  ? -3.282  -47.289 119.595 1   130.855 ? 726  VAL   A HB   1 c 
ATOM   469  H HG11 . VAL   A 1 32  ? -2.048  -46.287 121.934 1   129.694 ? 726  VAL   A HG11 1 c 
ATOM   470  H HG12 . VAL   A 1 32  ? -1.839  -45.628 120.506 1   129.62  ? 726  VAL   A HG12 1 c 
ATOM   471  H HG13 . VAL   A 1 32  ? -1.341  -47.104 120.773 1   130.117 ? 726  VAL   A HG13 1 c 
ATOM   472  H HG21 . VAL   A 1 32  ? -3.178  -48.971 121.087 1   128.1   ? 726  VAL   A HG21 1 c 
ATOM   473  H HG22 . VAL   A 1 32  ? -4.68   -48.475 121.162 1   127.735 ? 726  VAL   A HG22 1 c 
ATOM   474  H HG23 . VAL   A 1 32  ? -3.645  -48.048 122.288 1   127.758 ? 726  VAL   A HG23 1 c 
ATOM   475  N N    . TYR   A 1 33  ? -6.559  -46.645 121.604 1   122.939 ? 727  TYR   A N    1 ? 
ATOM   476  C CA   . TYR   A 1 33  ? -7.586  -46.731 122.628 1   121.856 ? 727  TYR   A CA   1 ? 
ATOM   477  C C    . TYR   A 1 33  ? -7.758  -48.177 123.085 1   105.093 ? 727  TYR   A C    1 ? 
ATOM   478  O O    . TYR   A 1 33  ? -7.628  -49.111 122.308 1   109.734 ? 727  TYR   A O    1 ? 
ATOM   479  C CB   . TYR   A 1 33  ? -8.943  -46.264 122.09  1   127.901 ? 727  TYR   A CB   1 ? 
ATOM   480  C CG   . TYR   A 1 33  ? -8.975  -44.813 121.643 1   132.775 ? 727  TYR   A CG   1 ? 
ATOM   481  C CD1  . TYR   A 1 33  ? -9.372  -43.806 122.508 1   127.975 ? 727  TYR   A CD1  1 ? 
ATOM   482  C CD2  . TYR   A 1 33  ? -8.618  -44.457 120.346 1   141.092 ? 727  TYR   A CD2  1 ? 
ATOM   483  C CE1  . TYR   A 1 33  ? -9.408  -42.487 122.091 1   134.13  ? 727  TYR   A CE1  1 ? 
ATOM   484  C CE2  . TYR   A 1 33  ? -8.649  -43.142 119.921 1   142.987 ? 727  TYR   A CE2  1 ? 
ATOM   485  C CZ   . TYR   A 1 33  ? -9.032  -42.153 120.801 1   139.711 ? 727  TYR   A CZ   1 ? 
ATOM   486  O OH   . TYR   A 1 33  ? -9.055  -40.867 120.356 1   160.969 ? 727  TYR   A OH   1 ? 
ATOM   487  H H    . TYR   A 1 33  ? -6.732  -47.027 120.793 1   120.526 ? 727  TYR   A H    1 c 
ATOM   488  H HA   . TYR   A 1 33  ? -7.328  -46.166 123.402 1   119.606 ? 727  TYR   A HA   1 c 
ATOM   489  H HB2  . TYR   A 1 33  ? -9.19   -46.835 121.329 1   127.282 ? 727  TYR   A HB2  1 c 
ATOM   490  H HB3  . TYR   A 1 33  ? -9.618  -46.393 122.793 1   127.399 ? 727  TYR   A HB3  1 c 
ATOM   491  H HD1  . TYR   A 1 33  ? -9.622  -44.022 123.393 1   130.719 ? 727  TYR   A HD1  1 c 
ATOM   492  H HD2  . TYR   A 1 33  ? -8.346  -45.13  119.742 1   139.443 ? 727  TYR   A HD2  1 c 
ATOM   493  H HE1  . TYR   A 1 33  ? -9.672  -41.811 122.692 1   134.137 ? 727  TYR   A HE1  1 c 
ATOM   494  H HE2  . TYR   A 1 33  ? -8.396  -42.921 119.041 1   141.746 ? 727  TYR   A HE2  1 c 
ATOM   495  H HH   . TYR   A 1 33  ? -9.349  -40.362 121.015 0   158.37  ? 727  TYR   A HH   1 c 
ATOM   496  N N    . LYS   A 1 34  ? -8.062  -48.345 124.367 1   103.565 ? 728  LYS   A N    1 ? 
ATOM   497  C CA   . LYS   A 1 34  ? -8.634  -49.578 124.867 1   111.136 ? 728  LYS   A CA   1 ? 
ATOM   498  C C    . LYS   A 1 34  ? -10.071 -49.625 124.37  1   101.994 ? 728  LYS   A C    1 ? 
ATOM   499  O O    . LYS   A 1 34  ? -10.705 -48.578 124.288 1   114.712 ? 728  LYS   A O    1 ? 
ATOM   500  C CB   . LYS   A 1 34  ? -8.596  -49.566 126.398 1   132.465 ? 728  LYS   A CB   1 ? 
ATOM   501  C CG   . LYS   A 1 34  ? -9.183  -50.768 127.106 1   143.904 ? 728  LYS   A CG   1 ? 
ATOM   502  C CD   . LYS   A 1 34  ? -8.948  -50.665 128.606 1   152.006 ? 728  LYS   A CD   1 ? 
ATOM   503  C CE   . LYS   A 1 34  ? -10.128 -51.114 129.388 1   159.019 ? 728  LYS   A CE   1 ? 
ATOM   504  N NZ   . LYS   A 1 34  ? -9.928  -50.873 130.82  1   163.328 ? 728  LYS   A NZ   1 ? 
ATOM   505  H H    . LYS   A 1 34  ? -7.913  -47.661 124.954 1   106.303 ? 728  LYS   A H    1 c 
ATOM   506  H HA   . LYS   A 1 34  ? -8.124  -50.347 124.505 1   111.225 ? 728  LYS   A HA   1 c 
ATOM   507  H HB2  . LYS   A 1 34  ? -7.663  -49.475 126.678 1   129.602 ? 728  LYS   A HB2  1 c 
ATOM   508  H HB3  . LYS   A 1 34  ? -9.073  -48.768 126.709 1   129.663 ? 728  LYS   A HB3  1 c 
ATOM   509  H HG2  . LYS   A 1 34  ? -10.146 -50.812 126.923 1   142.916 ? 728  LYS   A HG2  1 c 
ATOM   510  H HG3  . LYS   A 1 34  ? -8.759  -51.584 126.761 1   142.947 ? 728  LYS   A HG3  1 c 
ATOM   511  H HD2  . LYS   A 1 34  ? -8.174  -51.218 128.849 1   151.683 ? 728  LYS   A HD2  1 c 
ATOM   512  H HD3  . LYS   A 1 34  ? -8.743  -49.733 128.839 1   151.515 ? 728  LYS   A HD3  1 c 
ATOM   513  H HE2  . LYS   A 1 34  ? -10.921 -50.63  129.094 1   158.262 ? 728  LYS   A HE2  1 c 
ATOM   514  H HE3  . LYS   A 1 34  ? -10.277 -52.065 129.242 1   158.35  ? 728  LYS   A HE3  1 c 
ATOM   515  H HZ1  . LYS   A 1 34  ? -9.432  -50.126 130.951 1   161.95  ? 728  LYS   A HZ1  1 c 
ATOM   516  H HZ2  . LYS   A 1 34  ? -9.504  -51.579 131.187 1   162.203 ? 728  LYS   A HZ2  1 c 
ATOM   517  H HZ3  . LYS   A 1 34  ? -10.732 -50.763 131.222 1   162.267 ? 728  LYS   A HZ3  1 c 
ATOM   518  N N    . GLY   A 1 35  ? -10.587 -50.818 124.057 1   99.955  ? 729  GLY   A N    1 ? 
ATOM   519  C CA   . GLY   A 1 35  ? -11.891 -50.889 123.425 1   90.838  ? 729  GLY   A CA   1 ? 
ATOM   520  C C    . GLY   A 1 35  ? -12.568 -52.245 123.538 1   88.873  ? 729  GLY   A C    1 ? 
ATOM   521  O O    . GLY   A 1 35  ? -11.968 -53.228 123.946 1   99.266  ? 729  GLY   A O    1 ? 
ATOM   522  H H    . GLY   A 1 35  ? -10.127 -51.588 124.237 1   98.411  ? 729  GLY   A H    1 c 
ATOM   523  H HA2  . GLY   A 1 35  ? -12.476 -50.208 123.832 1   92.902  ? 729  GLY   A HA2  1 c 
ATOM   524  H HA3  . GLY   A 1 35  ? -11.79  -50.662 122.475 1   92.779  ? 729  GLY   A HA3  1 c 
ATOM   525  N N    . LEU   A 1 36  ? -13.842 -52.258 123.148 1   98.642  ? 730  LEU   A N    1 ? 
ATOM   526  C CA   . LEU   A 1 36  ? -14.646 -53.465 123.081 1   110.887 ? 730  LEU   A CA   1 ? 
ATOM   527  C C    . LEU   A 1 36  ? -15.208 -53.62  121.677 1   98.027  ? 730  LEU   A C    1 ? 
ATOM   528  O O    . LEU   A 1 36  ? -15.735 -52.663 121.14  1   108.499 ? 730  LEU   A O    1 ? 
ATOM   529  C CB   . LEU   A 1 36  ? -15.792 -53.404 124.089 1   126.412 ? 730  LEU   A CB   1 ? 
ATOM   530  C CG   . LEU   A 1 36  ? -15.626 -54.25  125.35  1   124.409 ? 730  LEU   A CG   1 ? 
ATOM   531  C CD1  . LEU   A 1 36  ? -16.981 -54.568 125.966 1   142.197 ? 730  LEU   A CD1  1 ? 
ATOM   532  C CD2  . LEU   A 1 36  ? -14.848 -55.504 125.03  1   120.802 ? 730  LEU   A CD2  1 ? 
ATOM   533  H H    . LEU   A 1 36  ? -14.233 -51.466 122.909 1   98.7    ? 730  LEU   A H    1 c 
ATOM   534  H HA   . LEU   A 1 36  ? -14.067 -54.237 123.275 1   108.546 ? 730  LEU   A HA   1 c 
ATOM   535  H HB2  . LEU   A 1 36  ? -15.912 -52.464 124.36  1   122.071 ? 730  LEU   A HB2  1 c 
ATOM   536  H HB3  . LEU   A 1 36  ? -16.619 -53.685 123.634 1   122.228 ? 730  LEU   A HB3  1 c 
ATOM   537  H HG   . LEU   A 1 36  ? -15.104 -53.723 126.01  1   127.205 ? 730  LEU   A HG   1 c 
ATOM   538  H HD11 . LEU   A 1 36  ? -17.448 -53.741 126.171 1   136.643 ? 730  LEU   A HD11 1 c 
ATOM   539  H HD12 . LEU   A 1 36  ? -16.855 -55.079 126.783 1   136.563 ? 730  LEU   A HD12 1 c 
ATOM   540  H HD13 . LEU   A 1 36  ? -17.509 -55.089 125.337 1   136.563 ? 730  LEU   A HD13 1 c 
ATOM   541  H HD21 . LEU   A 1 36  ? -13.9   -55.298 124.979 1   121.466 ? 730  LEU   A HD21 1 c 
ATOM   542  H HD22 . LEU   A 1 36  ? -15.15  -55.871 124.181 1   121.664 ? 730  LEU   A HD22 1 c 
ATOM   543  H HD23 . LEU   A 1 36  ? -14.994 -56.161 125.732 1   121.935 ? 730  LEU   A HD23 1 c 
ATOM   544  N N    . TRP   A 1 37  ? -15.141 -54.831 121.121 1   101.285 ? 731  TRP   A N    1 ? 
ATOM   545  C CA   . TRP   A 1 37  ? -15.641 -55.088 119.781 1   102.986 ? 731  TRP   A CA   1 ? 
ATOM   546  C C    . TRP   A 1 37  ? -16.689 -56.194 119.798 1   101.079 ? 731  TRP   A C    1 ? 
ATOM   547  O O    . TRP   A 1 37  ? -16.413 -57.289 120.281 1   97.126  ? 731  TRP   A O    1 ? 
ATOM   548  C CB   . TRP   A 1 37  ? -14.485 -55.457 118.84  1   101.966 ? 731  TRP   A CB   1 ? 
ATOM   549  C CG   . TRP   A 1 37  ? -14.95  -55.899 117.481 1   103.683 ? 731  TRP   A CG   1 ? 
ATOM   550  C CD1  . TRP   A 1 37  ? -15.953 -55.355 116.735 1   120.452 ? 731  TRP   A CD1  1 ? 
ATOM   551  C CD2  . TRP   A 1 37  ? -14.439 -57.006 116.721 1   106.28  ? 731  TRP   A CD2  1 ? 
ATOM   552  N NE1  . TRP   A 1 37  ? -16.1   -56.045 115.564 1   116.162 ? 731  TRP   A NE1  1 ? 
ATOM   553  C CE2  . TRP   A 1 37  ? -15.183 -57.059 115.525 1   107.479 ? 731  TRP   A CE2  1 ? 
ATOM   554  C CE3  . TRP   A 1 37  ? -13.425 -57.945 116.93  1   117.071 ? 731  TRP   A CE3  1 ? 
ATOM   555  C CZ2  . TRP   A 1 37  ? -14.941 -58.015 114.545 1   106.229 ? 731  TRP   A CZ2  1 ? 
ATOM   556  C CZ3  . TRP   A 1 37  ? -13.165 -58.874 115.943 1   113.374 ? 731  TRP   A CZ3  1 ? 
ATOM   557  C CH2  . TRP   A 1 37  ? -13.935 -58.922 114.78  1   99.569  ? 731  TRP   A CH2  1 ? 
ATOM   558  H H    . TRP   A 1 37  ? -14.773 -55.522 121.592 1   101.004 ? 731  TRP   A H    1 c 
ATOM   559  H HA   . TRP   A 1 37  ? -16.064 -54.257 119.438 1   102.22  ? 731  TRP   A HA   1 c 
ATOM   560  H HB2  . TRP   A 1 37  ? -13.902 -54.675 118.739 1   102.591 ? 731  TRP   A HB2  1 c 
ATOM   561  H HB3  . TRP   A 1 37  ? -13.965 -56.18  119.251 1   102.591 ? 731  TRP   A HB3  1 c 
ATOM   562  H HD1  . TRP   A 1 37  ? -16.479 -54.614 116.987 1   115.079 ? 731  TRP   A HD1  1 c 
ATOM   563  H HE1  . TRP   A 1 37  ? -16.678 -55.862 114.937 1   114.887 ? 731  TRP   A HE1  1 c 
ATOM   564  H HE3  . TRP   A 1 37  ? -12.906 -57.92  117.715 1   113.431 ? 731  TRP   A HE3  1 c 
ATOM   565  H HZ2  . TRP   A 1 37  ? -15.447 -58.039 113.751 1   105.079 ? 731  TRP   A HZ2  1 c 
ATOM   566  H HZ3  . TRP   A 1 37  ? -12.5   -59.522 116.081 1   111.13  ? 731  TRP   A HZ3  1 c 
ATOM   567  H HH2  . TRP   A 1 37  ? -13.747 -59.578 114.132 1   104.342 ? 731  TRP   A HH2  1 c 
ATOM   568  N N    . ILE   A 1 38  ? -17.87  -55.896 119.238 1   107.888 ? 732  ILE   A N    1 ? 
ATOM   569  C CA   . ILE   A 1 38  ? -18.918 -56.887 119.058 1   118.29  ? 732  ILE   A CA   1 ? 
ATOM   570  C C    . ILE   A 1 38  ? -19.06  -57.148 117.573 1   117.924 ? 732  ILE   A C    1 ? 
ATOM   571  O O    . ILE   A 1 38  ? -19.355 -56.239 116.805 1   115.011 ? 732  ILE   A O    1 ? 
ATOM   572  C CB   . ILE   A 1 38  ? -20.263 -56.443 119.635 1   114.934 ? 732  ILE   A CB   1 ? 
ATOM   573  C CG1  . ILE   A 1 38  ? -20.086 -55.728 120.986 1   108.095 ? 732  ILE   A CG1  1 ? 
ATOM   574  C CG2  . ILE   A 1 38  ? -21.206 -57.649 119.683 1   114.868 ? 732  ILE   A CG2  1 ? 
ATOM   575  C CD1  . ILE   A 1 38  ? -20.703 -56.433 122.178 1   112.686 ? 732  ILE   A CD1  1 ? 
ATOM   576  H H    . ILE   A 1 38  ? -18.028 -55.04  118.959 1   108.359 ? 732  ILE   A H    1 c 
ATOM   577  H HA   . ILE   A 1 38  ? -18.653 -57.709 119.505 1   115.437 ? 732  ILE   A HA   1 c 
ATOM   578  H HB   . ILE   A 1 38  ? -20.648 -55.794 119.014 1   114.254 ? 732  ILE   A HB   1 c 
ATOM   579  H HG12 . ILE   A 1 38  ? -19.13  -55.613 121.16  1   110.636 ? 732  ILE   A HG12 1 c 
ATOM   580  H HG13 . ILE   A 1 38  ? -20.481 -54.835 120.916 1   110.655 ? 732  ILE   A HG13 1 c 
ATOM   581  H HG21 . ILE   A 1 38  ? -22.054 -57.385 120.078 1   114.832 ? 732  ILE   A HG21 1 c 
ATOM   582  H HG22 . ILE   A 1 38  ? -20.808 -58.357 120.216 1   114.792 ? 732  ILE   A HG22 1 c 
ATOM   583  H HG23 . ILE   A 1 38  ? -21.362 -57.976 118.782 1   114.873 ? 732  ILE   A HG23 1 c 
ATOM   584  H HD11 . ILE   A 1 38  ? -21.677 -56.373 122.13  1   111.384 ? 732  ILE   A HD11 1 c 
ATOM   585  H HD12 . ILE   A 1 38  ? -20.395 -56.007 123     1   111.349 ? 732  ILE   A HD12 1 c 
ATOM   586  H HD13 . ILE   A 1 38  ? -20.436 -57.37  122.181 1   111.449 ? 732  ILE   A HD13 1 c 
ATOM   587  N N    . PRO   A 1 39  ? -18.661 -58.347 117.133 1   122.393 ? 733  PRO   A N    1 ? 
ATOM   588  C CA   . PRO   A 1 39  ? -18.803 -58.722 115.736 1   125.824 ? 733  PRO   A CA   1 ? 
ATOM   589  C C    . PRO   A 1 39  ? -20.234 -59.043 115.293 1   138.648 ? 733  PRO   A C    1 ? 
ATOM   590  O O    . PRO   A 1 39  ? -20.727 -60.125 115.58  1   147.097 ? 733  PRO   A O    1 ? 
ATOM   591  C CB   . PRO   A 1 39  ? -17.856 -59.918 115.629 1   134.128 ? 733  PRO   A CB   1 ? 
ATOM   592  C CG   . PRO   A 1 39  ? -16.9   -59.797 116.805 1   123.756 ? 733  PRO   A CG   1 ? 
ATOM   593  C CD   . PRO   A 1 39  ? -17.721 -59.195 117.884 1   128.939 ? 733  PRO   A CD   1 ? 
ATOM   594  H HA   . PRO   A 1 39  ? -18.453 -57.998 115.176 1   128.885 ? 733  PRO   A HA   1 c 
ATOM   595  H HB2  . PRO   A 1 39  ? -18.347 -60.758 115.674 1   130.146 ? 733  PRO   A HB2  1 c 
ATOM   596  H HB3  . PRO   A 1 39  ? -17.366 -59.894 114.784 1   129.888 ? 733  PRO   A HB3  1 c 
ATOM   597  H HG2  . PRO   A 1 39  ? -16.565 -60.675 117.075 1   127.113 ? 733  PRO   A HG2  1 c 
ATOM   598  H HG3  . PRO   A 1 39  ? -16.144 -59.224 116.586 1   126.726 ? 733  PRO   A HG3  1 c 
ATOM   599  H HD2  . PRO   A 1 39  ? -18.198 -59.877 118.392 1   125.909 ? 733  PRO   A HD2  1 c 
ATOM   600  H HD3  . PRO   A 1 39  ? -17.17  -58.666 118.485 1   125.642 ? 733  PRO   A HD3  1 c 
ATOM   601  N N    . GLU   A 1 40  ? -20.878 -58.103 114.575 1   155.537 ? 734  GLU   A N    1 ? 
ATOM   602  C CA   . GLU   A 1 40  ? -21.999 -58.382 113.672 1   160.954 ? 734  GLU   A CA   1 ? 
ATOM   603  C C    . GLU   A 1 40  ? -23.105 -59.205 114.348 1   148.502 ? 734  GLU   A C    1 ? 
ATOM   604  O O    . GLU   A 1 40  ? -23.606 -58.806 115.395 1   140.305 ? 734  GLU   A O    1 ? 
ATOM   605  C CB   . GLU   A 1 40  ? -21.499 -59.04  112.378 1   170.191 ? 734  GLU   A CB   1 ? 
ATOM   606  C CG   . GLU   A 1 40  ? -20.925 -58.07  111.35  1   172.902 ? 734  GLU   A CG   1 ? 
ATOM   607  C CD   . GLU   A 1 40  ? -21.924 -57.018 110.902 1   182.493 ? 734  GLU   A CD   1 ? 
ATOM   608  O OE1  . GLU   A 1 40  ? -21.5   -56.098 110.175 1   184.288 ? 734  GLU   A OE1  1 ? 
ATOM   609  O OE2  . GLU   A 1 40  ? -23.115 -57.11  111.282 1   179.819 ? 734  GLU   A OE2  1 ? 
ATOM   610  H H    . GLU   A 1 40  ? -20.601 -57.235 114.657 1   152.097 ? 734  GLU   A H    1 c 
ATOM   611  H HA   . GLU   A 1 40  ? -22.395 -57.511 113.429 1   159.387 ? 734  GLU   A HA   1 c 
ATOM   612  H HB2  . GLU   A 1 40  ? -20.823 -59.713 112.602 1   168.382 ? 734  GLU   A HB2  1 c 
ATOM   613  H HB3  . GLU   A 1 40  ? -22.244 -59.499 111.941 1   167.985 ? 734  GLU   A HB3  1 c 
ATOM   614  H HG2  . GLU   A 1 40  ? -20.145 -57.623 111.733 1   174.154 ? 734  GLU   A HG2  1 c 
ATOM   615  H HG3  . GLU   A 1 40  ? -20.627 -58.574 110.564 1   174.376 ? 734  GLU   A HG3  1 c 
ATOM   616  N N    . GLY   A 1 41  ? -23.488 -60.345 113.737 1   132.462 ? 735  GLY   A N    1 ? 
ATOM   617  C CA   . GLY   A 1 41  ? -24.59  -61.178 114.198 1   123.596 ? 735  GLY   A CA   1 ? 
ATOM   618  C C    . GLY   A 1 41  ? -24.225 -61.99  115.44  1   133.527 ? 735  GLY   A C    1 ? 
ATOM   619  O O    . GLY   A 1 41  ? -24.956 -61.97  116.422 1   137.707 ? 735  GLY   A O    1 ? 
ATOM   620  H H    . GLY   A 1 41  ? -23.022 -60.629 113.005 1   134.727 ? 735  GLY   A H    1 c 
ATOM   621  H HA2  . GLY   A 1 41  ? -25.365 -60.602 114.399 1   127.89  ? 735  GLY   A HA2  1 c 
ATOM   622  H HA3  . GLY   A 1 41  ? -24.852 -61.792 113.472 1   127.843 ? 735  GLY   A HA3  1 c 
ATOM   623  N N    . GLU   A 1 42  ? -23.107 -62.722 115.38  1   151.121 ? 736  GLU   A N    1 ? 
ATOM   624  C CA   . GLU   A 1 42  ? -22.524 -63.378 116.546 1   149.676 ? 736  GLU   A CA   1 ? 
ATOM   625  C C    . GLU   A 1 42  ? -22.589 -62.478 117.782 1   144.701 ? 736  GLU   A C    1 ? 
ATOM   626  O O    . GLU   A 1 42  ? -22.423 -61.264 117.669 1   152.287 ? 736  GLU   A O    1 ? 
ATOM   627  C CB   . GLU   A 1 42  ? -21.078 -63.791 116.268 1   141.689 ? 736  GLU   A CB   1 ? 
ATOM   628  C CG   . GLU   A 1 42  ? -20.241 -62.764 115.506 1   144.42  ? 736  GLU   A CG   1 ? 
ATOM   629  C CD   . GLU   A 1 42  ? -19.182 -63.425 114.654 1   142.943 ? 736  GLU   A CD   1 ? 
ATOM   630  O OE1  . GLU   A 1 42  ? -18.992 -64.644 114.86  1   126.369 ? 736  GLU   A OE1  1 ? 
ATOM   631  O OE2  . GLU   A 1 42  ? -18.575 -62.752 113.783 1   147.436 ? 736  GLU   A OE2  1 ? 
ATOM   632  H H    . GLU   A 1 42  ? -22.71  -62.844 114.566 1   146.08  ? 736  GLU   A H    1 c 
ATOM   633  H HA   . GLU   A 1 42  ? -23.049 -64.198 116.728 1   147.322 ? 736  GLU   A HA   1 c 
ATOM   634  H HB2  . GLU   A 1 42  ? -20.635 -63.972 117.123 1   144.071 ? 736  GLU   A HB2  1 c 
ATOM   635  H HB3  . GLU   A 1 42  ? -21.094 -64.629 115.761 1   143.961 ? 736  GLU   A HB3  1 c 
ATOM   636  H HG2  . GLU   A 1 42  ? -20.819 -62.229 114.928 1   143.54  ? 736  GLU   A HG2  1 c 
ATOM   637  H HG3  . GLU   A 1 42  ? -19.803 -62.169 116.148 1   143.383 ? 736  GLU   A HG3  1 c 
ATOM   638  N N    . LYS   A 1 43  ? -22.808 -63.099 118.948 1   127.827 ? 737  LYS   A N    1 ? 
ATOM   639  C CA   . LYS   A 1 43  ? -22.859 -62.389 120.221 1   136.904 ? 737  LYS   A CA   1 ? 
ATOM   640  C C    . LYS   A 1 43  ? -21.606 -62.708 121.045 1   130.292 ? 737  LYS   A C    1 ? 
ATOM   641  O O    . LYS   A 1 43  ? -21.637 -63.544 121.944 1   119.219 ? 737  LYS   A O    1 ? 
ATOM   642  C CB   . LYS   A 1 43  ? -24.143 -62.704 121.003 1   141.033 ? 737  LYS   A CB   1 ? 
ATOM   643  C CG   . LYS   A 1 43  ? -24.1   -63.934 121.91  1   141.907 ? 737  LYS   A CG   1 ? 
ATOM   644  C CD   . LYS   A 1 43  ? -25.447 -64.251 122.526 1   140.966 ? 737  LYS   A CD   1 ? 
ATOM   645  C CE   . LYS   A 1 43  ? -25.721 -63.627 123.865 1   149.547 ? 737  LYS   A CE   1 ? 
ATOM   646  N NZ   . LYS   A 1 43  ? -25.868 -64.628 124.926 1   161.135 ? 737  LYS   A NZ   1 ? 
ATOM   647  H H    . LYS   A 1 43  ? -22.93  -64.004 118.951 1   133.925 ? 737  LYS   A H    1 c 
ATOM   648  H HA   . LYS   A 1 43  ? -22.859 -61.417 120.032 1   134.694 ? 737  LYS   A HA   1 c 
ATOM   649  H HB2  . LYS   A 1 43  ? -24.367 -61.925 121.556 1   140.288 ? 737  LYS   A HB2  1 c 
ATOM   650  H HB3  . LYS   A 1 43  ? -24.873 -62.826 120.358 1   140.303 ? 737  LYS   A HB3  1 c 
ATOM   651  H HG2  . LYS   A 1 43  ? -23.795 -64.706 121.386 1   141.314 ? 737  LYS   A HG2  1 c 
ATOM   652  H HG3  . LYS   A 1 43  ? -23.456 -63.776 122.632 1   141.287 ? 737  LYS   A HG3  1 c 
ATOM   653  H HD2  . LYS   A 1 43  ? -26.148 -63.967 121.9   1   143.141 ? 737  LYS   A HD2  1 c 
ATOM   654  H HD3  . LYS   A 1 43  ? -25.521 -65.226 122.614 1   143.39  ? 737  LYS   A HD3  1 c 
ATOM   655  H HE2  . LYS   A 1 43  ? -24.994 -63.023 124.102 1   150.07  ? 737  LYS   A HE2  1 c 
ATOM   656  H HE3  . LYS   A 1 43  ? -26.54  -63.103 123.812 1   150.152 ? 737  LYS   A HE3  1 c 
ATOM   657  H HZ1  . LYS   A 1 43  ? -25.122 -65.141 124.97  1   157.352 ? 737  LYS   A HZ1  1 c 
ATOM   658  H HZ2  . LYS   A 1 43  ? -26.583 -65.157 124.751 1   157.352 ? 737  LYS   A HZ2  1 c 
ATOM   659  H HZ3  . LYS   A 1 43  ? -25.993 -64.214 125.722 1   157.427 ? 737  LYS   A HZ3  1 c 
ATOM   660  N N    . VAL   A 1 44  ? -20.496 -62.023 120.75  1   126.798 ? 738  VAL   A N    1 ? 
ATOM   661  C CA   . VAL   A 1 44  ? -19.295 -62.129 121.569 1   115.888 ? 738  VAL   A CA   1 ? 
ATOM   662  C C    . VAL   A 1 44  ? -18.688 -60.737 121.716 1   108.482 ? 738  VAL   A C    1 ? 
ATOM   663  O O    . VAL   A 1 44  ? -18.823 -59.905 120.829 1   105.331 ? 738  VAL   A O    1 ? 
ATOM   664  C CB   . VAL   A 1 44  ? -18.256 -63.099 120.971 1   121.024 ? 738  VAL   A CB   1 ? 
ATOM   665  C CG1  . VAL   A 1 44  ? -18.889 -64.369 120.42  1   134.935 ? 738  VAL   A CG1  1 ? 
ATOM   666  C CG2  . VAL   A 1 44  ? -17.403 -62.437 119.899 1   116.167 ? 738  VAL   A CG2  1 ? 
ATOM   667  H H    . VAL   A 1 44  ? -20.486 -61.476 120.018 1   125.097 ? 738  VAL   A H    1 c 
ATOM   668  H HA   . VAL   A 1 44  ? -19.548 -62.452 122.456 1   117.445 ? 738  VAL   A HA   1 c 
ATOM   669  H HB   . VAL   A 1 44  ? -17.654 -63.364 121.706 1   121.589 ? 738  VAL   A HB   1 c 
ATOM   670  H HG11 . VAL   A 1 44  ? -19.435 -64.151 119.645 1   130.632 ? 738  VAL   A HG11 1 c 
ATOM   671  H HG12 . VAL   A 1 44  ? -19.446 -64.778 121.103 1   130.598 ? 738  VAL   A HG12 1 c 
ATOM   672  H HG13 . VAL   A 1 44  ? -18.191 -64.992 120.157 1   130.646 ? 738  VAL   A HG13 1 c 
ATOM   673  H HG21 . VAL   A 1 44  ? -16.865 -63.111 119.45  1   117.589 ? 738  VAL   A HG21 1 c 
ATOM   674  H HG22 . VAL   A 1 44  ? -16.818 -61.78  120.31  1   117.238 ? 738  VAL   A HG22 1 c 
ATOM   675  H HG23 . VAL   A 1 44  ? -17.978 -61.998 119.249 1   117.528 ? 738  VAL   A HG23 1 c 
ATOM   676  N N    . LYS   A 1 45  ? -17.971 -60.493 122.811 1   108.024 ? 739  LYS   A N    1 ? 
ATOM   677  C CA   . LYS   A 1 45  ? -17.282 -59.229 122.989 1   106.94  ? 739  LYS   A CA   1 ? 
ATOM   678  C C    . LYS   A 1 45  ? -15.777 -59.48  123.034 1   103.38  ? 739  LYS   A C    1 ? 
ATOM   679  O O    . LYS   A 1 45  ? -15.286 -60.264 123.841 1   123.599 ? 739  LYS   A O    1 ? 
ATOM   680  C CB   . LYS   A 1 45  ? -17.743 -58.537 124.274 1   117.946 ? 739  LYS   A CB   1 ? 
ATOM   681  C CG   . LYS   A 1 45  ? -19.234 -58.624 124.584 1   120.06  ? 739  LYS   A CG   1 ? 
ATOM   682  C CD   . LYS   A 1 45  ? -19.637 -57.696 125.723 1   125.227 ? 739  LYS   A CD   1 ? 
ATOM   683  C CE   . LYS   A 1 45  ? -21.11  -57.476 125.836 1   121.06  ? 739  LYS   A CE   1 ? 
ATOM   684  N NZ   . LYS   A 1 45  ? -21.465 -56.487 126.865 1   129.96  ? 739  LYS   A NZ   1 ? 
ATOM   685  H H    . LYS   A 1 45  ? -17.908 -61.13  123.464 1   108.011 ? 739  LYS   A H    1 c 
ATOM   686  H HA   . LYS   A 1 45  ? -17.488 -58.642 122.22  1   108.279 ? 739  LYS   A HA   1 c 
ATOM   687  H HB2  . LYS   A 1 45  ? -17.252 -58.926 125.029 1   115.788 ? 739  LYS   A HB2  1 c 
ATOM   688  H HB3  . LYS   A 1 45  ? -17.496 -57.59  124.219 1   115.852 ? 739  LYS   A HB3  1 c 
ATOM   689  H HG2  . LYS   A 1 45  ? -19.741 -58.392 123.779 1   120.581 ? 739  LYS   A HG2  1 c 
ATOM   690  H HG3  . LYS   A 1 45  ? -19.454 -59.549 124.828 1   120.63  ? 739  LYS   A HG3  1 c 
ATOM   691  H HD2  . LYS   A 1 45  ? -19.309 -58.082 126.558 1   123.192 ? 739  LYS   A HD2  1 c 
ATOM   692  H HD3  . LYS   A 1 45  ? -19.193 -56.829 125.598 1   123.042 ? 739  LYS   A HD3  1 c 
ATOM   693  H HE2  . LYS   A 1 45  ? -21.454 -57.171 124.977 1   124.061 ? 739  LYS   A HE2  1 c 
ATOM   694  H HE3  . LYS   A 1 45  ? -21.545 -58.321 126.049 1   124.06  ? 739  LYS   A HE3  1 c 
ATOM   695  H HZ1  . LYS   A 1 45  ? -20.756 -55.956 127.054 1   127.183 ? 739  LYS   A HZ1  1 c 
ATOM   696  H HZ2  . LYS   A 1 45  ? -21.734 -56.91  127.619 1   127.22  ? 739  LYS   A HZ2  1 c 
ATOM   697  H HZ3  . LYS   A 1 45  ? -22.146 -55.97  126.563 1   127.171 ? 739  LYS   A HZ3  1 c 
ATOM   698  N N    . ILE   A 1 46  ? -15.039 -58.793 122.166 1   104.947 ? 740  ILE   A N    1 ? 
ATOM   699  C CA   . ILE   A 1 46  ? -13.6   -58.976 122.075 1   104.847 ? 740  ILE   A CA   1 ? 
ATOM   700  C C    . ILE   A 1 46  ? -12.896 -57.717 122.569 1   97.383  ? 740  ILE   A C    1 ? 
ATOM   701  O O    . ILE   A 1 46  ? -13.116 -56.621 122.066 1   101.356 ? 740  ILE   A O    1 ? 
ATOM   702  C CB   . ILE   A 1 46  ? -13.163 -59.321 120.641 1   104.649 ? 740  ILE   A CB   1 ? 
ATOM   703  C CG1  . ILE   A 1 46  ? -13.508 -60.766 120.272 1   96.168  ? 740  ILE   A CG1  1 ? 
ATOM   704  C CG2  . ILE   A 1 46  ? -11.682 -59.011 120.432 1   101.368 ? 740  ILE   A CG2  1 ? 
ATOM   705  C CD1  . ILE   A 1 46  ? -14.57  -60.874 119.195 1   104.789 ? 740  ILE   A CD1  1 ? 
ATOM   706  H H    . ILE   A 1 46  ? -15.441 -58.188 121.611 1   104.598 ? 740  ILE   A H    1 c 
ATOM   707  H HA   . ILE   A 1 46  ? -13.349 -59.719 122.649 1   103.362 ? 740  ILE   A HA   1 c 
ATOM   708  H HB   . ILE   A 1 46  ? -13.669 -58.74  120.038 1   102.443 ? 740  ILE   A HB   1 c 
ATOM   709  H HG12 . ILE   A 1 46  ? -12.696 -61.218 119.963 1   100.037 ? 740  ILE   A HG12 1 c 
ATOM   710  H HG13 . ILE   A 1 46  ? -13.823 -61.231 121.073 1   100.188 ? 740  ILE   A HG13 1 c 
ATOM   711  H HG21 . ILE   A 1 46  ? -11.406 -59.322 119.553 1   102.319 ? 740  ILE   A HG21 1 c 
ATOM   712  H HG22 . ILE   A 1 46  ? -11.155 -59.464 121.112 1   102.313 ? 740  ILE   A HG22 1 c 
ATOM   713  H HG23 . ILE   A 1 46  ? -11.534 -58.056 120.493 1   102.396 ? 740  ILE   A HG23 1 c 
ATOM   714  H HD11 . ILE   A 1 46  ? -15.354 -60.355 119.454 1   102.313 ? 740  ILE   A HD11 1 c 
ATOM   715  H HD12 . ILE   A 1 46  ? -14.822 -61.809 119.077 1   102.352 ? 740  ILE   A HD12 1 c 
ATOM   716  H HD13 . ILE   A 1 46  ? -14.216 -60.526 118.354 1   102.226 ? 740  ILE   A HD13 1 c 
ATOM   717  N N    . PRO   A 1 47  ? -12.022 -57.836 123.581 1   99.567  ? 741  PRO   A N    1 ? 
ATOM   718  C CA   . PRO   A 1 47  ? -11.196 -56.714 123.992 1   93.851  ? 741  PRO   A CA   1 ? 
ATOM   719  C C    . PRO   A 1 47  ? -10.208 -56.323 122.903 1   94.645  ? 741  PRO   A C    1 ? 
ATOM   720  O O    . PRO   A 1 47  ? -9.485  -57.188 122.424 1   100.383 ? 741  PRO   A O    1 ? 
ATOM   721  C CB   . PRO   A 1 47  ? -10.461 -57.258 125.211 1   89.782  ? 741  PRO   A CB   1 ? 
ATOM   722  C CG   . PRO   A 1 47  ? -11.27  -58.468 125.643 1   85.859  ? 741  PRO   A CG   1 ? 
ATOM   723  C CD   . PRO   A 1 47  ? -11.818 -59.039 124.398 1   96.83   ? 741  PRO   A CD   1 ? 
ATOM   724  H HA   . PRO   A 1 47  ? -11.758 -55.95  124.236 1   94.515  ? 741  PRO   A HA   1 c 
ATOM   725  H HB2  . PRO   A 1 47  ? -9.547  -57.516 124.984 1   89.862  ? 741  PRO   A HB2  1 c 
ATOM   726  H HB3  . PRO   A 1 47  ? -10.43  -56.59  125.923 1   89.838  ? 741  PRO   A HB3  1 c 
ATOM   727  H HG2  . PRO   A 1 47  ? -10.703 -59.121 126.099 1   89.185  ? 741  PRO   A HG2  1 c 
ATOM   728  H HG3  . PRO   A 1 47  ? -11.994 -58.205 126.246 1   89.185  ? 741  PRO   A HG3  1 c 
ATOM   729  H HD2  . PRO   A 1 47  ? -11.185 -59.649 123.972 1   94.923  ? 741  PRO   A HD2  1 c 
ATOM   730  H HD3  . PRO   A 1 47  ? -12.661 -59.503 124.563 1   94.931  ? 741  PRO   A HD3  1 c 
ATOM   731  N N    . VAL   A 1 48  ? -10.165 -55.039 122.527 1   93.649  ? 742  VAL   A N    1 ? 
ATOM   732  C CA   . VAL   A 1 48  ? -9.312  -54.624 121.42  1   101.355 ? 742  VAL   A CA   1 ? 
ATOM   733  C C    . VAL   A 1 48  ? -8.486  -53.395 121.788 1   97.942  ? 742  VAL   A C    1 ? 
ATOM   734  O O    . VAL   A 1 48  ? -8.851  -52.632 122.683 1   105.992 ? 742  VAL   A O    1 ? 
ATOM   735  C CB   . VAL   A 1 48  ? -10.128 -54.362 120.141 1   104.335 ? 742  VAL   A CB   1 ? 
ATOM   736  C CG1  . VAL   A 1 48  ? -10.64  -55.664 119.551 1   113.197 ? 742  VAL   A CG1  1 ? 
ATOM   737  C CG2  . VAL   A 1 48  ? -11.288 -53.404 120.379 1   111.042 ? 742  VAL   A CG2  1 ? 
ATOM   738  H H    . VAL   A 1 48  ? -10.667 -54.413 122.965 1   95.675  ? 742  VAL   A H    1 c 
ATOM   739  H HA   . VAL   A 1 48  ? -8.692  -55.353 121.234 1   99.741  ? 742  VAL   A HA   1 c 
ATOM   740  H HB   . VAL   A 1 48  ? -9.519  -53.949 119.486 1   106.55  ? 742  VAL   A HB   1 c 
ATOM   741  H HG11 . VAL   A 1 48  ? -11.36  -56.006 120.106 1   110.385 ? 742  VAL   A HG11 1 c 
ATOM   742  H HG12 . VAL   A 1 48  ? -9.918  -56.312 119.523 1   110.458 ? 742  VAL   A HG12 1 c 
ATOM   743  H HG13 . VAL   A 1 48  ? -10.974 -55.508 118.653 1   110.561 ? 742  VAL   A HG13 1 c 
ATOM   744  H HG21 . VAL   A 1 48  ? -11.755 -53.244 119.541 1   108.962 ? 742  VAL   A HG21 1 c 
ATOM   745  H HG22 . VAL   A 1 48  ? -10.95  -52.561 120.725 1   108.919 ? 742  VAL   A HG22 1 c 
ATOM   746  H HG23 . VAL   A 1 48  ? -11.905 -53.792 121.022 1   108.818 ? 742  VAL   A HG23 1 c 
ATOM   747  N N    . ALA   A 1 49  ? -7.383  -53.222 121.053 1   93.474  ? 743  ALA   A N    1 ? 
ATOM   748  C CA   . ALA   A 1 49  ? -6.652  -51.974 121.022 1   97.431  ? 743  ALA   A CA   1 ? 
ATOM   749  C C    . ALA   A 1 49  ? -6.939  -51.282 119.695 1   95.66   ? 743  ALA   A C    1 ? 
ATOM   750  O O    . ALA   A 1 49  ? -6.635  -51.844 118.649 1   97.219  ? 743  ALA   A O    1 ? 
ATOM   751  C CB   . ALA   A 1 49  ? -5.183  -52.25  121.195 1   106.685 ? 743  ALA   A CB   1 ? 
ATOM   752  H H    . ALA   A 1 49  ? -7.074  -53.919 120.549 1   95.455  ? 743  ALA   A H    1 c 
ATOM   753  H HA   . ALA   A 1 49  ? -6.971  -51.395 121.764 1   98.109  ? 743  ALA   A HA   1 c 
ATOM   754  H HB1  . ALA   A 1 49  ? -5.016  -52.576 122.095 1   103.884 ? 743  ALA   A HB1  1 c 
ATOM   755  H HB2  . ALA   A 1 49  ? -4.898  -52.921 120.554 1   104.038 ? 743  ALA   A HB2  1 c 
ATOM   756  H HB3  . ALA   A 1 49  ? -4.677  -51.432 121.051 1   103.885 ? 743  ALA   A HB3  1 c 
ATOM   757  N N    . ILE   A 1 50  ? -7.548  -50.09  119.749 1   103.063 ? 744  ILE   A N    1 ? 
ATOM   758  C CA   . ILE   A 1 50  ? -7.883  -49.346 118.545 1   104.322 ? 744  ILE   A CA   1 ? 
ATOM   759  C C    . ILE   A 1 50  ? -6.884  -48.213 118.377 1   99.217  ? 744  ILE   A C    1 ? 
ATOM   760  O O    . ILE   A 1 50  ? -6.774  -47.379 119.259 1   113.236 ? 744  ILE   A O    1 ? 
ATOM   761  C CB   . ILE   A 1 50  ? -9.307  -48.78  118.608 1   104.56  ? 744  ILE   A CB   1 ? 
ATOM   762  C CG1  . ILE   A 1 50  ? -10.318 -49.873 118.898 1   106.101 ? 744  ILE   A CG1  1 ? 
ATOM   763  C CG2  . ILE   A 1 50  ? -9.624  -48.018 117.319 1   114.828 ? 744  ILE   A CG2  1 ? 
ATOM   764  C CD1  . ILE   A 1 50  ? -11.216 -49.568 120.077 1   105.763 ? 744  ILE   A CD1  1 ? 
ATOM   765  H H    . ILE   A 1 50  ? -7.761  -49.729 120.562 1   101.464 ? 744  ILE   A H    1 c 
ATOM   766  H HA   . ILE   A 1 50  ? -7.821  -49.942 117.778 1   103.213 ? 744  ILE   A HA   1 c 
ATOM   767  H HB   . ILE   A 1 50  ? -9.339  -48.141 119.348 1   106.748 ? 744  ILE   A HB   1 c 
ATOM   768  H HG12 . ILE   A 1 50  ? -10.875 -50.006 118.105 1   105.756 ? 744  ILE   A HG12 1 c 
ATOM   769  H HG13 . ILE   A 1 50  ? -9.843  -50.711 119.073 1   105.664 ? 744  ILE   A HG13 1 c 
ATOM   770  H HG21 . ILE   A 1 50  ? -10.575 -47.817 117.286 1   111.653 ? 744  ILE   A HG21 1 c 
ATOM   771  H HG22 . ILE   A 1 50  ? -9.384  -48.564 116.551 1   111.686 ? 744  ILE   A HG22 1 c 
ATOM   772  H HG23 . ILE   A 1 50  ? -9.12   -47.188 117.296 1   111.632 ? 744  ILE   A HG23 1 c 
ATOM   773  H HD11 . ILE   A 1 50  ? -10.673 -49.454 120.88  1   105.736 ? 744  ILE   A HD11 1 c 
ATOM   774  H HD12 . ILE   A 1 50  ? -11.842 -50.305 120.21  1   105.736 ? 744  ILE   A HD12 1 c 
ATOM   775  H HD13 . ILE   A 1 50  ? -11.715 -48.747 119.905 1   105.814 ? 744  ILE   A HD13 1 c 
ATOM   776  N N    . LYS   A 1 51  ? -6.193  -48.179 117.238 1   105.645 ? 745  LYS   A N    1 ? 
ATOM   777  C CA   . LYS   A 1 51  ? -5.236  -47.129 116.941 1   117.571 ? 745  LYS   A CA   1 ? 
ATOM   778  C C    . LYS   A 1 51  ? -5.734  -46.332 115.736 1   137.29  ? 745  LYS   A C    1 ? 
ATOM   779  O O    . LYS   A 1 51  ? -6.061  -46.932 114.715 1   146.056 ? 745  LYS   A O    1 ? 
ATOM   780  C CB   . LYS   A 1 51  ? -3.876  -47.799 116.745 1   111.07  ? 745  LYS   A CB   1 ? 
ATOM   781  C CG   . LYS   A 1 51  ? -3.205  -47.44  115.453 1   131.84  ? 745  LYS   A CG   1 ? 
ATOM   782  C CD   . LYS   A 1 51  ? -1.71   -47.26  115.622 1   125.512 ? 745  LYS   A CD   1 ? 
ATOM   783  C CE   . LYS   A 1 51  ? -0.899  -48.519 115.705 1   108.952 ? 745  LYS   A CE   1 ? 
ATOM   784  N NZ   . LYS   A 1 51  ? 0.466   -48.138 115.34  1   109.313 ? 745  LYS   A NZ   1 ? 
ATOM   785  H H    . LYS   A 1 51  ? -6.326  -48.837 116.617 1   106.654 ? 745  LYS   A H    1 c 
ATOM   786  H HA   . LYS   A 1 51  ? -5.179  -46.522 117.718 1   117.528 ? 745  LYS   A HA   1 c 
ATOM   787  H HB2  . LYS   A 1 51  ? -3.288  -47.543 117.486 1   117.24  ? 745  LYS   A HB2  1 c 
ATOM   788  H HB3  . LYS   A 1 51  ? -3.99   -48.773 116.777 1   116.959 ? 745  LYS   A HB3  1 c 
ATOM   789  H HG2  . LYS   A 1 51  ? -3.375  -48.152 114.798 1   125.194 ? 745  LYS   A HG2  1 c 
ATOM   790  H HG3  . LYS   A 1 51  ? -3.588  -46.606 115.109 1   125.429 ? 745  LYS   A HG3  1 c 
ATOM   791  H HD2  . LYS   A 1 51  ? -1.383  -46.727 114.864 1   122.627 ? 745  LYS   A HD2  1 c 
ATOM   792  H HD3  . LYS   A 1 51  ? -1.55   -46.73  116.432 1   122.682 ? 745  LYS   A HD3  1 c 
ATOM   793  H HE2  . LYS   A 1 51  ? -0.911  -48.878 116.611 1   112.598 ? 745  LYS   A HE2  1 c 
ATOM   794  H HE3  . LYS   A 1 51  ? -1.234  -49.19  115.085 1   112.659 ? 745  LYS   A HE3  1 c 
ATOM   795  H HZ1  . LYS   A 1 51  ? 0.72    -47.401 115.803 1   109.32  ? 745  LYS   A HZ1  1 c 
ATOM   796  H HZ2  . LYS   A 1 51  ? 0.51    -47.962 114.452 1   109.316 ? 745  LYS   A HZ2  1 c 
ATOM   797  H HZ3  . LYS   A 1 51  ? 1.033   -48.818 115.534 1   109.246 ? 745  LYS   A HZ3  1 c 
ATOM   798  N N    . GLU   A 1 52  ? -5.822  -44.995 115.875 1   145.994 ? 746  GLU   A N    1 ? 
ATOM   799  C CA   . GLU   A 1 52  ? -6.332  -44.131 114.815 1   152.968 ? 746  GLU   A CA   1 ? 
ATOM   800  C C    . GLU   A 1 52  ? -5.505  -42.848 114.719 1   151.919 ? 746  GLU   A C    1 ? 
ATOM   801  O O    . GLU   A 1 52  ? -4.85   -42.495 115.687 1   162.379 ? 746  GLU   A O    1 ? 
ATOM   802  C CB   . GLU   A 1 52  ? -7.809  -43.823 115.052 1   148.88  ? 746  GLU   A CB   1 ? 
ATOM   803  C CG   . GLU   A 1 52  ? -8.082  -42.555 115.855 1   146.512 ? 746  GLU   A CG   1 ? 
ATOM   804  C CD   . GLU   A 1 52  ? -9.565  -42.247 115.965 1   154.134 ? 746  GLU   A CD   1 ? 
ATOM   805  O OE1  . GLU   A 1 52  ? -10.063 -42.009 117.084 1   148.313 ? 746  GLU   A OE1  1 ? 
ATOM   806  O OE2  . GLU   A 1 52  ? -10.233 -42.262 114.91  1   166.91  ? 746  GLU   A OE2  1 ? 
ATOM   807  H H    . GLU   A 1 52  ? -5.554  -44.61  116.66  1   144.948 ? 746  GLU   A H    1 c 
ATOM   808  H HA   . GLU   A 1 52  ? -6.25   -44.614 113.954 1   150.542 ? 746  GLU   A HA   1 c 
ATOM   809  H HB2  . GLU   A 1 52  ? -8.249  -43.735 114.181 1   149.155 ? 746  GLU   A HB2  1 c 
ATOM   810  H HB3  . GLU   A 1 52  ? -8.217  -44.582 115.518 1   149.079 ? 746  GLU   A HB3  1 c 
ATOM   811  H HG2  . GLU   A 1 52  ? -7.711  -42.656 116.757 1   148.848 ? 746  GLU   A HG2  1 c 
ATOM   812  H HG3  . GLU   A 1 52  ? -7.639  -41.796 115.423 1   148.924 ? 746  GLU   A HG3  1 c 
ATOM   813  N N    . LEU   A 1 53  ? -5.603  -42.124 113.584 1   173.311 ? 747  LEU   A N    1 ? 
ATOM   814  C CA   . LEU   A 1 53  ? -4.701  -41.023 113.236 1   188.355 ? 747  LEU   A CA   1 ? 
ATOM   815  C C    . LEU   A 1 53  ? -5.275  -39.674 113.684 1   201.089 ? 747  LEU   A C    1 ? 
ATOM   816  O O    . LEU   A 1 53  ? -6.452  -39.408 113.44  1   204.269 ? 747  LEU   A O    1 ? 
ATOM   817  C CB   . LEU   A 1 53  ? -4.452  -40.983 111.726 1   181.739 ? 747  LEU   A CB   1 ? 
ATOM   818  C CG   . LEU   A 1 53  ? -3.827  -42.222 111.068 1   164.381 ? 747  LEU   A CG   1 ? 
ATOM   819  C CD1  . LEU   A 1 53  ? -2.397  -42.521 111.494 1   147.925 ? 747  LEU   A CD1  1 ? 
ATOM   820  C CD2  . LEU   A 1 53  ? -4.698  -43.428 111.311 1   165.669 ? 747  LEU   A CD2  1 ? 
ATOM   821  H H    . LEU   A 1 53  ? -6.293  -42.31  113.016 1   170.851 ? 747  LEU   A H    1 c 
ATOM   822  H HA   . LEU   A 1 53  ? -3.839  -41.17  113.701 1   186.135 ? 747  LEU   A HA   1 c 
ATOM   823  H HB2  . LEU   A 1 53  ? -5.312  -40.802 111.282 1   179.118 ? 747  LEU   A HB2  1 c 
ATOM   824  H HB3  . LEU   A 1 53  ? -3.87   -40.21  111.536 1   179.208 ? 747  LEU   A HB3  1 c 
ATOM   825  H HG   . LEU   A 1 53  ? -3.812  -42.064 110.088 1   164.409 ? 747  LEU   A HG   1 c 
ATOM   826  H HD11 . LEU   A 1 53  ? -1.827  -41.765 111.273 1   152.597 ? 747  LEU   A HD11 1 c 
ATOM   827  H HD12 . LEU   A 1 53  ? -2.079  -43.313 111.03  1   152.597 ? 747  LEU   A HD12 1 c 
ATOM   828  H HD13 . LEU   A 1 53  ? -2.37   -42.675 112.454 1   152.597 ? 747  LEU   A HD13 1 c 
ATOM   829  H HD21 . LEU   A 1 53  ? -5.63   -43.182 111.197 1   165.266 ? 747  LEU   A HD21 1 c 
ATOM   830  H HD22 . LEU   A 1 53  ? -4.555  -43.76  112.212 1   165.204 ? 747  LEU   A HD22 1 c 
ATOM   831  H HD23 . LEU   A 1 53  ? -4.469  -44.124 110.672 1   165.265 ? 747  LEU   A HD23 1 c 
ATOM   832  N N    . ARG   A 1 54  ? -4.396  -38.792 114.219 1   212.826 ? 748  ARG   A N    1 ? 
ATOM   833  C CA   . ARG   A 1 54  ? -4.758  -37.55  114.905 1   219.311 ? 748  ARG   A CA   1 ? 
ATOM   834  C C    . ARG   A 1 54  ? -4.525  -36.312 114.024 1   236.533 ? 748  ARG   A C    1 ? 
ATOM   835  O O    . ARG   A 1 54  ? -5.393  -35.441 113.978 1   248.179 ? 748  ARG   A O    1 ? 
ATOM   836  C CB   . ARG   A 1 54  ? -3.991  -37.417 116.231 1   210.089 ? 748  ARG   A CB   1 ? 
ATOM   837  C CG   . ARG   A 1 54  ? -2.568  -36.878 116.13  1   205.037 ? 748  ARG   A CG   1 ? 
ATOM   838  C CD   . ARG   A 1 54  ? -1.707  -37.173 117.341 1   204.861 ? 748  ARG   A CD   1 ? 
ATOM   839  N NE   . ARG   A 1 54  ? -2.483  -37.272 118.58  1   216.532 ? 748  ARG   A NE   1 ? 
ATOM   840  C CZ   . ARG   A 1 54  ? -2.102  -36.885 119.787 1   209.974 ? 748  ARG   A CZ   1 ? 
ATOM   841  N NH1  . ARG   A 1 54  ? -0.92   -36.328 119.992 1   208.171 ? 748  ARG   A NH1  1 ? 
ATOM   842  N NH2  . ARG   A 1 54  ? -2.917  -37.079 120.808 1   192.371 ? 748  ARG   A NH2  1 ? 
ATOM   843  H H    . ARG   A 1 54  ? -3.506  -38.988 114.146 1   211.136 ? 748  ARG   A H    1 c 
ATOM   844  H HA   . ARG   A 1 54  ? -5.725  -37.593 115.121 1   219.303 ? 748  ARG   A HA   1 c 
ATOM   845  H HB2  . ARG   A 1 54  ? -4.506  -36.829 116.824 1   211.003 ? 748  ARG   A HB2  1 c 
ATOM   846  H HB3  . ARG   A 1 54  ? -3.959  -38.303 116.651 1   211.009 ? 748  ARG   A HB3  1 c 
ATOM   847  H HG2  . ARG   A 1 54  ? -2.136  -37.269 115.341 1   206.273 ? 748  ARG   A HG2  1 c 
ATOM   848  H HG3  . ARG   A 1 54  ? -2.603  -35.906 115.998 1   206.289 ? 748  ARG   A HG3  1 c 
ATOM   849  H HD2  . ARG   A 1 54  ? -1.231  -38.015 117.195 1   207.342 ? 748  ARG   A HD2  1 c 
ATOM   850  H HD3  . ARG   A 1 54  ? -1.041  -36.463 117.43  1   207.565 ? 748  ARG   A HD3  1 c 
ATOM   851  H HE   . ARG   A 1 54  ? -3.271  -37.632 118.532 1   211.115 ? 748  ARG   A HE   1 c 
ATOM   852  H HH11 . ARG   A 1 54  ? -0.536  -35.841 119.364 1   208.418 ? 748  ARG   A HH11 1 c 
ATOM   853  H HH12 . ARG   A 1 54  ? -0.525  -36.43  120.776 1   207.552 ? 748  ARG   A HH12 1 c 
ATOM   854  H HH21 . ARG   A 1 54  ? -3.679  -37.512 120.694 1   197.917 ? 748  ARG   A HH21 1 c 
ATOM   855  H HH22 . ARG   A 1 54  ? -2.697  -36.773 121.609 1   197.84  ? 748  ARG   A HH22 1 c 
ATOM   856  N N    . GLU   A 1 55  ? -3.37   -36.226 113.327 1   236.557 ? 749  GLU   A N    1 ? 
ATOM   857  C CA   . GLU   A 1 55  ? -3.025  -35.07  112.495 1   206.115 ? 749  GLU   A CA   1 ? 
ATOM   858  C C    . GLU   A 1 55  ? -3.714  -35.194 111.128 1   204.092 ? 749  GLU   A C    1 ? 
ATOM   859  O O    . GLU   A 1 55  ? -3.036  -35.324 110.106 1   201.213 ? 749  GLU   A O    1 ? 
ATOM   860  C CB   . GLU   A 1 55  ? -1.505  -34.876 112.39  1   155.987 ? 749  GLU   A CB   1 ? 
ATOM   861  H H    . GLU   A 1 55  ? -2.786  -36.928 113.356 1   228.088 ? 749  GLU   A H    1 c 
ATOM   862  H HA   . GLU   A 1 55  ? -3.386  -34.261 112.94  1   201.031 ? 749  GLU   A HA   1 c 
ATOM   863  H HB2  . GLU   A 1 55  ? -1.061  -35.433 113.063 0   164.89  ? 749  GLU   A HB2  1 c 
ATOM   864  H HB3  . GLU   A 1 55  ? -1.288  -34.429 111.517 0   164.89  ? 749  GLU   A HB3  1 c 
ATOM   865  N N    . ALA   A 1 56  ? -5.065  -35.137 111.152 1   201.322 ? 750  ALA   A N    1 ? 
ATOM   866  C CA   . ALA   A 1 56  ? -5.968  -35.248 110.007 1   187.45  ? 750  ALA   A CA   1 ? 
ATOM   867  C C    . ALA   A 1 56  ? -5.751  -36.562 109.241 1   189.585 ? 750  ALA   A C    1 ? 
ATOM   868  O O    . ALA   A 1 56  ? -5.37   -37.57  109.851 1   153.28  ? 750  ALA   A O    1 ? 
ATOM   869  C CB   . ALA   A 1 56  ? -5.851  -34.011 109.126 1   165.751 ? 750  ALA   A CB   1 ? 
ATOM   870  H H    . ALA   A 1 56  ? -5.453  -35.002 111.968 1   198.986 ? 750  ALA   A H    1 c 
ATOM   871  H HA   . ALA   A 1 56  ? -6.896  -35.274 110.37  1   186.197 ? 750  ALA   A HA   1 c 
ATOM   872  H HB1  . ALA   A 1 56  ? -5.738  -33.223 109.685 1   171.902 ? 750  ALA   A HB1  1 c 
ATOM   873  H HB2  . ALA   A 1 56  ? -5.082  -34.099 108.538 1   171.954 ? 750  ALA   A HB2  1 c 
ATOM   874  H HB3  . ALA   A 1 56  ? -6.657  -33.91  108.591 1   171.963 ? 750  ALA   A HB3  1 c 
ATOM   875  N N    . THR   A 1 57  ? -6.058  -36.546 107.921 1   185.658 ? 751  THR   A N    1 ? 
ATOM   876  C CA   . THR   A 1 57  ? -5.781  -37.634 106.985 1   169.545 ? 751  THR   A CA   1 ? 
ATOM   877  C C    . THR   A 1 57  ? -4.606  -37.25  106.072 1   172.016 ? 751  THR   A C    1 ? 
ATOM   878  O O    . THR   A 1 57  ? -4.787  -37.049 104.873 1   183.047 ? 751  THR   A O    1 ? 
ATOM   879  C CB   . THR   A 1 57  ? -7.044  -37.96  106.18  1   146.126 ? 751  THR   A CB   1 ? 
ATOM   880  H H    . THR   A 1 57  ? -6.48   -35.806 107.591 1   182.326 ? 751  THR   A H    1 c 
ATOM   881  H HA   . THR   A 1 57  ? -5.528  -38.43  107.501 1   168.379 ? 751  THR   A HA   1 c 
ATOM   882  H HB   . THR   A 1 57  ? -7.841  -37.789 106.645 0   149.65  ? 751  THR   A HB   1 c 
ATOM   883  N N    . SER   A 1 58  ? -3.406  -37.13  106.67  1   158.362 ? 752  SER   A N    1 ? 
ATOM   884  C CA   . SER   A 1 58  ? -2.131  -37.017 105.97  1   148.105 ? 752  SER   A CA   1 ? 
ATOM   885  C C    . SER   A 1 58  ? -1.976  -38.183 104.986 0.8 158.853 ? 752  SER   A C    1 ? 
ATOM   886  O O    . SER   A 1 58  ? -1.876  -39.331 105.413 0.8 151.536 ? 752  SER   A O    1 ? 
ATOM   887  C CB   . SER   A 1 58  ? -0.988  -36.961 106.989 1   134.456 ? 752  SER   A CB   1 ? 
ATOM   888  O OG   . SER   A 1 58  ? 0.288   -37.184 106.404 1   144.663 ? 752  SER   A OG   1 ? 
ATOM   889  H H    . SER   A 1 58  ? -3.391  -37.116 107.583 1   159.071 ? 752  SER   A H    1 c 
ATOM   890  H HA   . SER   A 1 58  ? -2.134  -36.171 105.46  1   149.292 ? 752  SER   A HA   1 c 
ATOM   891  H HB2  . SER   A 1 58  ? -0.992  -36.085 107.42  1   139.858 ? 752  SER   A HB2  1 c 
ATOM   892  H HB3  . SER   A 1 58  ? -1.144  -37.631 107.68  1   140.035 ? 752  SER   A HB3  1 c 
ATOM   893  H HG   . SER   A 1 58  ? 0.879   -37.142 107.012 0   145.07  ? 752  SER   A HG   1 c 
ATOM   894  N N    . PRO   A 1 59  ? -1.989  -37.958 103.645 0.8 157.438 ? 753  PRO   A N    1 ? 
ATOM   895  C CA   . PRO   A 1 59  ? -1.805  -39.044 102.691 0.8 150.938 ? 753  PRO   A CA   1 ? 
ATOM   896  C C    . PRO   A 1 59  ? -0.422  -39.674 102.813 0.8 155.042 ? 753  PRO   A C    1 ? 
ATOM   897  O O    . PRO   A 1 59  ? -0.292  -40.894 102.764 0.8 142.731 ? 753  PRO   A O    1 ? 
ATOM   898  C CB   . PRO   A 1 59  ? -2.011  -38.389 101.324 0.8 146.238 ? 753  PRO   A CB   1 ? 
ATOM   899  C CG   . PRO   A 1 59  ? -2.677  -37.062 101.628 0.8 141.957 ? 753  PRO   A CG   1 ? 
ATOM   900  C CD   . PRO   A 1 59  ? -2.156  -36.661 102.972 0.8 147.575 ? 753  PRO   A CD   1 ? 
ATOM   901  H HA   . PRO   A 1 59  ? -2.492  -39.728 102.837 0.8 152.047 ? 753  PRO   A HA   1 c 
ATOM   902  H HB2  . PRO   A 1 59  ? -1.156  -38.252 100.871 0.8 146.337 ? 753  PRO   A HB2  1 c 
ATOM   903  H HB3  . PRO   A 1 59  ? -2.58   -38.942 100.755 0.8 146.297 ? 753  PRO   A HB3  1 c 
ATOM   904  H HG2  . PRO   A 1 59  ? -2.442  -36.393 100.955 0.8 144.188 ? 753  PRO   A HG2  1 c 
ATOM   905  H HG3  . PRO   A 1 59  ? -3.65   -37.159 101.652 0.8 144.188 ? 753  PRO   A HG3  1 c 
ATOM   906  H HD2  . PRO   A 1 59  ? -1.302  -36.192 102.901 0.8 148.535 ? 753  PRO   A HD2  1 c 
ATOM   907  H HD3  . PRO   A 1 59  ? -2.798  -36.099 103.446 0.8 148.665 ? 753  PRO   A HD3  1 c 
ATOM   908  N N    . LYS   A 1 60  ? 0.594   -38.813 102.988 1   156.483 ? 754  LYS   A N    1 ? 
ATOM   909  C CA   . LYS   A 1 60  ? 1.932   -39.231 103.385 1   159.303 ? 754  LYS   A CA   1 ? 
ATOM   910  C C    . LYS   A 1 60  ? 1.819   -40.336 104.437 1   158.674 ? 754  LYS   A C    1 ? 
ATOM   911  O O    . LYS   A 1 60  ? 2.281   -41.452 104.209 1   139.672 ? 754  LYS   A O    1 ? 
ATOM   912  C CB   . LYS   A 1 60  ? 2.737   -38.024 103.893 1   134.99  ? 754  LYS   A CB   1 ? 
ATOM   913  H H    . LYS   A 1 60  ? 0.444   -37.924 102.838 1   156.528 ? 754  LYS   A H    1 c 
ATOM   914  H HA   . LYS   A 1 60  ? 2.389   -39.602 102.587 1   153.833 ? 754  LYS   A HA   1 c 
ATOM   915  H HB2  . LYS   A 1 60  ? 3.704   -38.211 103.833 0   139.64  ? 754  LYS   A HB2  1 c 
ATOM   916  H HB3  . LYS   A 1 60  ? 2.109   -37.337 104.215 0   139.64  ? 754  LYS   A HB3  1 c 
ATOM   917  N N    . ALA   A 1 61  ? 1.123   -40.021 105.544 1   168.797 ? 755  ALA   A N    1 ? 
ATOM   918  C CA   . ALA   A 1 61  ? 1.1     -40.817 106.764 1   162.585 ? 755  ALA   A CA   1 ? 
ATOM   919  C C    . ALA   A 1 61  ? 0.313   -42.123 106.62  1   163.623 ? 755  ALA   A C    1 ? 
ATOM   920  O O    . ALA   A 1 61  ? 0.677   -43.083 107.269 1   152.025 ? 755  ALA   A O    1 ? 
ATOM   921  C CB   . ALA   A 1 61  ? 0.543   -39.986 107.906 1   150.97  ? 755  ALA   A CB   1 ? 
ATOM   922  H H    . ALA   A 1 61  ? 0.626   -39.253 105.531 1   164.485 ? 755  ALA   A H    1 c 
ATOM   923  H HA   . ALA   A 1 61  ? 2.043   -41.057 106.982 1   161.692 ? 755  ALA   A HA   1 c 
ATOM   924  H HB1  . ALA   A 1 61  ? 1.055   -39.164 107.993 1   154.229 ? 755  ALA   A HB1  1 c 
ATOM   925  H HB2  . ALA   A 1 61  ? -0.387  -39.768 107.728 1   154.186 ? 755  ALA   A HB2  1 c 
ATOM   926  H HB3  . ALA   A 1 61  ? 0.602   -40.49  108.735 1   154.271 ? 755  ALA   A HB3  1 c 
ATOM   927  N N    . ASN   A 1 62  ? -0.749  -42.183 105.799 1   172.397 ? 756  ASN   A N    1 ? 
ATOM   928  C CA   . ASN   A 1 62  ? -1.636  -43.345 105.738 1   147.947 ? 756  ASN   A CA   1 ? 
ATOM   929  C C    . ASN   A 1 62  ? -0.957  -44.574 105.137 1   129.5   ? 756  ASN   A C    1 ? 
ATOM   930  O O    . ASN   A 1 62  ? -1.364  -45.691 105.431 1   119.096 ? 756  ASN   A O    1 ? 
ATOM   931  C CB   . ASN   A 1 62  ? -2.92   -43.076 104.955 1   150.437 ? 756  ASN   A CB   1 ? 
ATOM   932  C CG   . ASN   A 1 62  ? -3.917  -42.284 105.76  1   149.302 ? 756  ASN   A CG   1 ? 
ATOM   933  O OD1  . ASN   A 1 62  ? -3.569  -41.753 106.816 1   154.264 ? 756  ASN   A OD1  1 ? 
ATOM   934  N ND2  . ASN   A 1 62  ? -5.146  -42.187 105.281 1   155.02  ? 756  ASN   A ND2  1 ? 
ATOM   935  H H    . ASN   A 1 62  ? -0.93   -41.469 105.256 1   164.315 ? 756  ASN   A H    1 c 
ATOM   936  H HA   . ASN   A 1 62  ? -1.898  -43.569 106.66  1   149.271 ? 756  ASN   A HA   1 c 
ATOM   937  H HB2  . ASN   A 1 62  ? -2.701  -42.583 104.139 1   149.676 ? 756  ASN   A HB2  1 c 
ATOM   938  H HB3  . ASN   A 1 62  ? -3.323  -43.929 104.695 1   149.498 ? 756  ASN   A HB3  1 c 
ATOM   939  H HD21 . ASN   A 1 62  ? -5.756  -41.717 105.721 1   153.24  ? 756  ASN   A HD21 1 c 
ATOM   940  H HD22 . ASN   A 1 62  ? -5.36   -42.593 104.521 1   153.219 ? 756  ASN   A HD22 1 c 
ATOM   941  N N    . LYS   A 1 63  ? 0.076   -44.378 104.31  1   135.793 ? 757  LYS   A N    1 ? 
ATOM   942  C CA   . LYS   A 1 63  ? 0.832   -45.484 103.741 1   135.907 ? 757  LYS   A CA   1 ? 
ATOM   943  C C    . LYS   A 1 63  ? 1.447   -46.332 104.862 1   137.576 ? 757  LYS   A C    1 ? 
ATOM   944  O O    . LYS   A 1 63  ? 1.5     -47.557 104.739 1   142.75  ? 757  LYS   A O    1 ? 
ATOM   945  C CB   . LYS   A 1 63  ? 1.874   -44.955 102.743 1   121.032 ? 757  LYS   A CB   1 ? 
ATOM   946  H H    . LYS   A 1 63  ? 0.311   -43.524 104.086 1   134.662 ? 757  LYS   A H    1 c 
ATOM   947  H HA   . LYS   A 1 63  ? 0.199   -46.052 103.238 1   133.434 ? 757  LYS   A HA   1 c 
ATOM   948  H HB2  . LYS   A 1 63  ? 2.812   -45.201 103.217 0   123.57  ? 757  LYS   A HB2  1 c 
ATOM   949  H HB3  . LYS   A 1 63  ? 1.493   -44.563 102.072 0   123.57  ? 757  LYS   A HB3  1 c 
ATOM   950  N N    . GLU   A 1 64  ? 1.915   -45.683 105.944 1   134.5   ? 758  GLU   A N    1 ? 
ATOM   951  C CA   . GLU   A 1 64  ? 2.569   -46.361 107.059 1   133.384 ? 758  GLU   A CA   1 ? 
ATOM   952  C C    . GLU   A 1 64  ? 1.546   -47.213 107.818 1   132.66  ? 758  GLU   A C    1 ? 
ATOM   953  O O    . GLU   A 1 64  ? 1.819   -48.36  108.177 1   143.139 ? 758  GLU   A O    1 ? 
ATOM   954  C CB   . GLU   A 1 64  ? 3.279   -45.355 107.976 1   107.714 ? 758  GLU   A CB   1 ? 
ATOM   955  H H    . GLU   A 1 64  ? 1.825   -44.775 105.982 1   134.752 ? 758  GLU   A H    1 c 
ATOM   956  H HA   . GLU   A 1 64  ? 3.257   -46.968 106.685 1   128.432 ? 758  GLU   A HA   1 c 
ATOM   957  H HB2  . GLU   A 1 64  ? 4.233   -45.487 107.968 0   115.14  ? 758  GLU   A HB2  1 c 
ATOM   958  H HB3  . GLU   A 1 64  ? 2.575   -44.869 108.532 0   115.14  ? 758  GLU   A HB3  1 c 
ATOM   959  N N    . ILE   A 1 65  ? 0.362   -46.64  108.062 1   124.379 ? 759  ILE   A N    1 ? 
ATOM   960  C CA   . ILE   A 1 65  ? -0.686  -47.288 108.829 1   130.683 ? 759  ILE   A CA   1 ? 
ATOM   961  C C    . ILE   A 1 65  ? -1.212  -48.502 108.059 1   130.369 ? 759  ILE   A C    1 ? 
ATOM   962  O O    . ILE   A 1 65  ? -1.478  -49.553 108.639 1   127.471 ? 759  ILE   A O    1 ? 
ATOM   963  C CB   . ILE   A 1 65  ? -1.816  -46.292 109.172 1   141.563 ? 759  ILE   A CB   1 ? 
ATOM   964  C CG1  . ILE   A 1 65  ? -2.477  -46.592 110.513 1   157.212 ? 759  ILE   A CG1  1 ? 
ATOM   965  C CG2  . ILE   A 1 65  ? -2.86   -46.189 108.061 1   155.387 ? 759  ILE   A CG2  1 ? 
ATOM   966  C CD1  . ILE   A 1 65  ? -2.077  -47.895 111.163 1   174.981 ? 759  ILE   A CD1  1 ? 
ATOM   967  H H    . ILE   A 1 65  ? 0.204   -45.802 107.734 1   127.929 ? 759  ILE   A H    1 c 
ATOM   968  H HA   . ILE   A 1 65  ? -0.289  -47.602 109.659 1   131.981 ? 759  ILE   A HA   1 c 
ATOM   969  H HB   . ILE   A 1 65  ? -1.401  -45.411 109.255 1   144.521 ? 759  ILE   A HB   1 c 
ATOM   970  H HG12 . ILE   A 1 65  ? -2.266  -45.862 111.13  1   157.321 ? 759  ILE   A HG12 1 c 
ATOM   971  H HG13 . ILE   A 1 65  ? -3.448  -46.596 110.386 1   157.283 ? 759  ILE   A HG13 1 c 
ATOM   972  H HG21 . ILE   A 1 65  ? -3.496  -45.487 108.28  1   150.956 ? 759  ILE   A HG21 1 c 
ATOM   973  H HG22 . ILE   A 1 65  ? -3.335  -47.033 107.975 1   150.728 ? 759  ILE   A HG22 1 c 
ATOM   974  H HG23 . ILE   A 1 65  ? -2.426  -45.976 107.224 1   150.268 ? 759  ILE   A HG23 1 c 
ATOM   975  H HD11 . ILE   A 1 65  ? -2.279  -48.637 110.567 1   167.824 ? 759  ILE   A HD11 1 c 
ATOM   976  H HD12 . ILE   A 1 65  ? -2.596  -47.99  111.984 1   168.542 ? 759  ILE   A HD12 1 c 
ATOM   977  H HD13 . ILE   A 1 65  ? -1.127  -47.899 111.384 1   168.447 ? 759  ILE   A HD13 1 c 
ATOM   978  N N    . LEU   A 1 66  ? -1.378  -48.349 106.744 1   128.133 ? 760  LEU   A N    1 ? 
ATOM   979  C CA   . LEU   A 1 66  ? -1.933  -49.414 105.928 1   114.496 ? 760  LEU   A CA   1 ? 
ATOM   980  C C    . LEU   A 1 66  ? -0.921  -50.523 105.692 1   113.135 ? 760  LEU   A C    1 ? 
ATOM   981  O O    . LEU   A 1 66  ? -1.31   -51.679 105.577 1   102.642 ? 760  LEU   A O    1 ? 
ATOM   982  C CB   . LEU   A 1 66  ? -2.394  -48.823 104.609 1   117.706 ? 760  LEU   A CB   1 ? 
ATOM   983  C CG   . LEU   A 1 66  ? -3.725  -48.087 104.699 1   112.34  ? 760  LEU   A CG   1 ? 
ATOM   984  C CD1  . LEU   A 1 66  ? -3.961  -47.397 103.384 1   125.426 ? 760  LEU   A CD1  1 ? 
ATOM   985  C CD2  . LEU   A 1 66  ? -4.835  -49.055 105.05  1   104.397 ? 760  LEU   A CD2  1 ? 
ATOM   986  H H    . LEU   A 1 66  ? -1.13   -47.567 106.343 1   125.659 ? 760  LEU   A H    1 c 
ATOM   987  H HA   . LEU   A 1 66  ? -2.71   -49.798 106.404 1   117.33  ? 760  LEU   A HA   1 c 
ATOM   988  H HB2  . LEU   A 1 66  ? -1.708  -48.191 104.296 1   116.235 ? 760  LEU   A HB2  1 c 
ATOM   989  H HB3  . LEU   A 1 66  ? -2.48   -49.551 103.951 1   115.753 ? 760  LEU   A HB3  1 c 
ATOM   990  H HG   . LEU   A 1 66  ? -3.661  -47.401 105.413 1   114.104 ? 760  LEU   A HG   1 c 
ATOM   991  H HD11 . LEU   A 1 66  ? -3.108  -47.158 102.982 1   121.278 ? 760  LEU   A HD11 1 c 
ATOM   992  H HD12 . LEU   A 1 66  ? -4.481  -46.59  103.531 1   121.323 ? 760  LEU   A HD12 1 c 
ATOM   993  H HD13 . LEU   A 1 66  ? -4.442  -47.992 102.785 1   121.244 ? 760  LEU   A HD13 1 c 
ATOM   994  H HD21 . LEU   A 1 66  ? -4.783  -49.285 105.993 1   106.836 ? 760  LEU   A HD21 1 c 
ATOM   995  H HD22 . LEU   A 1 66  ? -4.745  -49.862 104.515 1   106.837 ? 760  LEU   A HD22 1 c 
ATOM   996  H HD23 . LEU   A 1 66  ? -5.696  -48.641 104.867 1   106.747 ? 760  LEU   A HD23 1 c 
ATOM   997  N N    . ASP   A 1 67  ? 0.364   -50.17  105.613 1   116.533 ? 761  ASP   A N    1 ? 
ATOM   998  C CA   . ASP   A 1 67  ? 1.418   -51.166 105.503 1   119.94  ? 761  ASP   A CA   1 ? 
ATOM   999  C C    . ASP   A 1 67  ? 1.439   -52.046 106.747 1   112.232 ? 761  ASP   A C    1 ? 
ATOM   1000 O O    . ASP   A 1 67  ? 1.624   -53.256 106.662 1   105.078 ? 761  ASP   A O    1 ? 
ATOM   1001 C CB   . ASP   A 1 67  ? 2.765   -50.508 105.276 1   128.035 ? 761  ASP   A CB   1 ? 
ATOM   1002 C CG   . ASP   A 1 67  ? 3.003   -50.097 103.836 1   125.786 ? 761  ASP   A CG   1 ? 
ATOM   1003 O OD1  . ASP   A 1 67  ? 2.012   -49.879 103.115 1   132.07  ? 761  ASP   A OD1  1 ? 
ATOM   1004 O OD2  . ASP   A 1 67  ? 4.171   -50.077 103.436 1   136.416 ? 761  ASP   A OD2  1 ? 
ATOM   1005 H H    . ASP   A 1 67  ? 0.591   -49.285 105.618 1   116.676 ? 761  ASP   A H    1 c 
ATOM   1006 H HA   . ASP   A 1 67  ? 1.222   -51.736 104.725 1   119.235 ? 761  ASP   A HA   1 c 
ATOM   1007 H HB2  . ASP   A 1 67  ? 2.836   -49.712 105.843 1   125.564 ? 761  ASP   A HB2  1 c 
ATOM   1008 H HB3  . ASP   A 1 67  ? 3.475   -51.131 105.538 1   125.6   ? 761  ASP   A HB3  1 c 
ATOM   1009 N N    . GLU   A 1 68  ? 1.244   -51.413 107.903 1   118.752 ? 762  GLU   A N    1 ? 
ATOM   1010 C CA   . GLU   A 1 68  ? 1.194   -52.118 109.17  1   131.201 ? 762  GLU   A CA   1 ? 
ATOM   1011 C C    . GLU   A 1 68  ? 0.058   -53.14  109.136 1   120.608 ? 762  GLU   A C    1 ? 
ATOM   1012 O O    . GLU   A 1 68  ? 0.241   -54.28  109.553 1   127.642 ? 762  GLU   A O    1 ? 
ATOM   1013 C CB   . GLU   A 1 68  ? 1.015   -51.101 110.294 1   139.786 ? 762  GLU   A CB   1 ? 
ATOM   1014 C CG   . GLU   A 1 68  ? 1.317   -51.65  111.685 1   149.406 ? 762  GLU   A CG   1 ? 
ATOM   1015 C CD   . GLU   A 1 68  ? 1.195   -50.588 112.756 1   145.833 ? 762  GLU   A CD   1 ? 
ATOM   1016 O OE1  . GLU   A 1 68  ? 1.23    -49.378 112.434 1   126.042 ? 762  GLU   A OE1  1 ? 
ATOM   1017 O OE2  . GLU   A 1 68  ? 1.022   -50.977 113.924 1   150.314 ? 762  GLU   A OE2  1 ? 
ATOM   1018 H H    . GLU   A 1 68  ? 1.144   -50.504 107.903 1   120.089 ? 762  GLU   A H    1 c 
ATOM   1019 H HA   . GLU   A 1 68  ? 2.052   -52.597 109.297 1   128.167 ? 762  GLU   A HA   1 c 
ATOM   1020 H HB2  . GLU   A 1 68  ? 1.603   -50.336 110.122 1   139.479 ? 762  GLU   A HB2  1 c 
ATOM   1021 H HB3  . GLU   A 1 68  ? 0.091   -50.775 110.281 1   139.635 ? 762  GLU   A HB3  1 c 
ATOM   1022 H HG2  . GLU   A 1 68  ? 0.695   -52.38  111.889 1   146.235 ? 762  GLU   A HG2  1 c 
ATOM   1023 H HG3  . GLU   A 1 68  ? 2.229   -52.012 111.7   1   146.334 ? 762  GLU   A HG3  1 c 
ATOM   1024 N N    . ALA   A 1 69  ? -1.114  -52.705 108.651 1   118.367 ? 763  ALA   A N    1 ? 
ATOM   1025 C CA   . ALA   A 1 69  ? -2.291  -53.554 108.519 1   114.464 ? 763  ALA   A CA   1 ? 
ATOM   1026 C C    . ALA   A 1 69  ? -2.028  -54.717 107.56  1   104.214 ? 763  ALA   A C    1 ? 
ATOM   1027 O O    . ALA   A 1 69  ? -2.423  -55.856 107.82  1   92.386  ? 763  ALA   A O    1 ? 
ATOM   1028 C CB   . ALA   A 1 69  ? -3.475  -52.725 108.06  1   105.861 ? 763  ALA   A CB   1 ? 
ATOM   1029 H H    . ALA   A 1 69  ? -1.183  -51.83  108.396 1   117.999 ? 763  ALA   A H    1 c 
ATOM   1030 H HA   . ALA   A 1 69  ? -2.495  -53.936 109.416 1   111.642 ? 763  ALA   A HA   1 c 
ATOM   1031 H HB1  . ALA   A 1 69  ? -3.606  -51.978 108.668 1   108.79  ? 763  ALA   A HB1  1 c 
ATOM   1032 H HB2  . ALA   A 1 69  ? -3.309  -52.384 107.165 1   108.448 ? 763  ALA   A HB2  1 c 
ATOM   1033 H HB3  . ALA   A 1 69  ? -4.276  -53.276 108.05  1   108.633 ? 763  ALA   A HB3  1 c 
ATOM   1034 N N    . TYR   A 1 70  ? -1.364  -54.42  106.442 1   97.067  ? 764  TYR   A N    1 ? 
ATOM   1035 C CA   . TYR   A 1 70  ? -1.081  -55.435 105.445 1   97.995  ? 764  TYR   A CA   1 ? 
ATOM   1036 C C    . TYR   A 1 70  ? -0.251  -56.555 106.068 1   96.675  ? 764  TYR   A C    1 ? 
ATOM   1037 O O    . TYR   A 1 70  ? -0.518  -57.735 105.866 1   92.344  ? 764  TYR   A O    1 ? 
ATOM   1038 C CB   . TYR   A 1 70  ? -0.391  -54.811 104.228 1   95.043  ? 764  TYR   A CB   1 ? 
ATOM   1039 C CG   . TYR   A 1 70  ? 0.172   -55.867 103.291 1   94.113  ? 764  TYR   A CG   1 ? 
ATOM   1040 C CD1  . TYR   A 1 70  ? 1.456   -56.348 103.473 1   96.578  ? 764  TYR   A CD1  1 ? 
ATOM   1041 C CD2  . TYR   A 1 70  ? -0.588  -56.412 102.267 1   86.977  ? 764  TYR   A CD2  1 ? 
ATOM   1042 C CE1  . TYR   A 1 70  ? 1.99    -57.316 102.644 1   92.53   ? 764  TYR   A CE1  1 ? 
ATOM   1043 C CE2  . TYR   A 1 70  ? -0.066  -57.383 101.436 1   92.101  ? 764  TYR   A CE2  1 ? 
ATOM   1044 C CZ   . TYR   A 1 70  ? 1.223   -57.842 101.627 1   91.273  ? 764  TYR   A CZ   1 ? 
ATOM   1045 O OH   . TYR   A 1 70  ? 1.753   -58.812 100.836 1   103.575 ? 764  TYR   A OH   1 ? 
ATOM   1046 H H    . TYR   A 1 70  ? -1.085  -53.563 106.293 1   99.098  ? 764  TYR   A H    1 c 
ATOM   1047 H HA   . TYR   A 1 70  ? -1.941  -55.823 105.15  1   97.006  ? 764  TYR   A HA   1 c 
ATOM   1048 H HB2  . TYR   A 1 70  ? -1.043  -54.26  103.74  1   95.502  ? 764  TYR   A HB2  1 c 
ATOM   1049 H HB3  . TYR   A 1 70  ? 0.34    -54.232 104.537 1   95.559  ? 764  TYR   A HB3  1 c 
ATOM   1050 H HD1  . TYR   A 1 70  ? 1.987   -55.994 104.168 1   94.967  ? 764  TYR   A HD1  1 c 
ATOM   1051 H HD2  . TYR   A 1 70  ? -1.47   -56.107 102.128 1   89.899  ? 764  TYR   A HD2  1 c 
ATOM   1052 H HE1  . TYR   A 1 70  ? 2.867   -57.629 102.784 1   93.205  ? 764  TYR   A HE1  1 c 
ATOM   1053 H HE2  . TYR   A 1 70  ? -0.593  -57.74  100.744 1   90.823  ? 764  TYR   A HE2  1 c 
ATOM   1054 H HH   . TYR   A 1 70  ? 2.548   -58.968 101.058 0   105.59  ? 764  TYR   A HH   1 c 
ATOM   1055 N N    . VAL   A 1 71  ? 0.786   -56.174 106.812 1   107.757 ? 765  VAL   A N    1 ? 
ATOM   1056 C CA   . VAL   A 1 71  ? 1.711   -57.144 107.364 1   105.724 ? 765  VAL   A CA   1 ? 
ATOM   1057 C C    . VAL   A 1 71  ? 1.029   -57.953 108.463 1   104.322 ? 765  VAL   A C    1 ? 
ATOM   1058 O O    . VAL   A 1 71  ? 1.249   -59.168 108.563 1   104.706 ? 765  VAL   A O    1 ? 
ATOM   1059 C CB   . VAL   A 1 71  ? 2.976   -56.459 107.895 1   107.703 ? 765  VAL   A CB   1 ? 
ATOM   1060 C CG1  . VAL   A 1 71  ? 3.836   -57.455 108.641 1   129.626 ? 765  VAL   A CG1  1 ? 
ATOM   1061 C CG2  . VAL   A 1 71  ? 3.792   -55.814 106.788 1   112.154 ? 765  VAL   A CG2  1 ? 
ATOM   1062 H H    . VAL   A 1 71  ? 0.925   -55.286 106.978 1   104.526 ? 765  VAL   A H    1 c 
ATOM   1063 H HA   . VAL   A 1 71  ? 1.972   -57.757 106.649 1   106.085 ? 765  VAL   A HA   1 c 
ATOM   1064 H HB   . VAL   A 1 71  ? 2.692   -55.757 108.525 1   111.904 ? 765  VAL   A HB   1 c 
ATOM   1065 H HG11 . VAL   A 1 71  ? 3.857   -58.292 108.149 1   122.754 ? 765  VAL   A HG11 1 c 
ATOM   1066 H HG12 . VAL   A 1 71  ? 3.467   -57.608 109.527 1   122.604 ? 765  VAL   A HG12 1 c 
ATOM   1067 H HG13 . VAL   A 1 71  ? 4.737   -57.101 108.724 1   122.713 ? 765  VAL   A HG13 1 c 
ATOM   1068 H HG21 . VAL   A 1 71  ? 4.535   -55.322 107.177 1   110.885 ? 765  VAL   A HG21 1 c 
ATOM   1069 H HG22 . VAL   A 1 71  ? 3.23    -55.204 106.283 1   110.786 ? 765  VAL   A HG22 1 c 
ATOM   1070 H HG23 . VAL   A 1 71  ? 4.135   -56.503 106.195 1   110.825 ? 765  VAL   A HG23 1 c 
ATOM   1071 N N    . MET   A 1 72  ? 0.224   -57.261 109.285 1   100.146 ? 766  MET   A N    1 ? 
ATOM   1072 C CA   . MET   A 1 72  ? -0.384  -57.847 110.47  1   98.595  ? 766  MET   A CA   1 ? 
ATOM   1073 C C    . MET   A 1 72  ? -1.456  -58.867 110.117 1   90.289  ? 766  MET   A C    1 ? 
ATOM   1074 O O    . MET   A 1 72  ? -1.634  -59.831 110.85  1   105.421 ? 766  MET   A O    1 ? 
ATOM   1075 C CB   . MET   A 1 72  ? -1.02   -56.784 111.363 1   108.732 ? 766  MET   A CB   1 ? 
ATOM   1076 C CG   . MET   A 1 72  ? -0.354  -56.66  112.705 1   119.731 ? 766  MET   A CG   1 ? 
ATOM   1077 S SD   . MET   A 1 72  ? -0.758  -55.065 113.445 1   123.108 ? 766  MET   A SD   1 ? 
ATOM   1078 C CE   . MET   A 1 72  ? -1.619  -55.7   114.899 1   157.777 ? 766  MET   A CE   1 ? 
ATOM   1079 H H    . MET   A 1 72  ? 0.051   -56.384 109.095 1   100.973 ? 766  MET   A H    1 c 
ATOM   1080 H HA   . MET   A 1 72  ? 0.328   -58.314 110.976 1   99.358  ? 766  MET   A HA   1 c 
ATOM   1081 H HB2  . MET   A 1 72  ? -0.983  -55.918 110.905 1   108.775 ? 766  MET   A HB2  1 c 
ATOM   1082 H HB3  . MET   A 1 72  ? -1.962  -57.01  111.495 1   108.676 ? 766  MET   A HB3  1 c 
ATOM   1083 H HG2  . MET   A 1 72  ? -0.658  -57.379 113.293 1   118.036 ? 766  MET   A HG2  1 c 
ATOM   1084 H HG3  . MET   A 1 72  ? 0.614   -56.732 112.603 1   117.796 ? 766  MET   A HG3  1 c 
ATOM   1085 H HE1  . MET   A 1 72  ? -1.658  -55.005 115.58  1   147.474 ? 766  MET   A HE1  1 c 
ATOM   1086 H HE2  . MET   A 1 72  ? -2.521  -55.973 114.649 1   147.698 ? 766  MET   A HE2  1 c 
ATOM   1087 H HE3  . MET   A 1 72  ? -1.134  -56.467 115.255 1   147.765 ? 766  MET   A HE3  1 c 
ATOM   1088 N N    . ALA   A 1 73  ? -2.183  -58.623 109.024 1   93.389  ? 767  ALA   A N    1 ? 
ATOM   1089 C CA   . ALA   A 1 73  ? -3.195  -59.547 108.533 1   93.397  ? 767  ALA   A CA   1 ? 
ATOM   1090 C C    . ALA   A 1 73  ? -2.57   -60.837 107.995 1   87.712  ? 767  ALA   A C    1 ? 
ATOM   1091 O O    . ALA   A 1 73  ? -3.203  -61.883 107.987 1   99.063  ? 767  ALA   A O    1 ? 
ATOM   1092 C CB   . ALA   A 1 73  ? -3.999  -58.858 107.467 1   93.298  ? 767  ALA   A CB   1 ? 
ATOM   1093 H H    . ALA   A 1 73  ? -2.047  -57.844 108.566 1   92.737  ? 767  ALA   A H    1 c 
ATOM   1094 H HA   . ALA   A 1 73  ? -3.795  -59.784 109.293 1   92.366  ? 767  ALA   A HA   1 c 
ATOM   1095 H HB1  . ALA   A 1 73  ? -4.427  -58.069 107.839 1   93.484  ? 767  ALA   A HB1  1 c 
ATOM   1096 H HB2  . ALA   A 1 73  ? -3.415  -58.592 106.737 1   93.364  ? 767  ALA   A HB2  1 c 
ATOM   1097 H HB3  . ALA   A 1 73  ? -4.68   -59.463 107.129 1   93.364  ? 767  ALA   A HB3  1 c 
ATOM   1098 N N    . SER   A 1 74  ? -1.321  -60.763 107.548 1   84.464  ? 768  SER   A N    1 ? 
ATOM   1099 C CA   . SER   A 1 74  ? -0.688  -61.84  106.816 1   92.397  ? 768  SER   A CA   1 ? 
ATOM   1100 C C    . SER   A 1 74  ? 0.038   -62.793 107.757 1   94.905  ? 768  SER   A C    1 ? 
ATOM   1101 O O    . SER   A 1 74  ? 0.726   -63.703 107.298 1   101.21  ? 768  SER   A O    1 ? 
ATOM   1102 C CB   . SER   A 1 74  ? 0.261   -61.252 105.812 1   101.357 ? 768  SER   A CB   1 ? 
ATOM   1103 O OG   . SER   A 1 74  ? -0.299  -60.079 105.236 1   94.246  ? 768  SER   A OG   1 ? 
ATOM   1104 H H    . SER   A 1 74  ? -0.839  -60.001 107.697 1   87.258  ? 768  SER   A H    1 c 
ATOM   1105 H HA   . SER   A 1 74  ? -1.387  -62.348 106.331 1   92.805  ? 768  SER   A HA   1 c 
ATOM   1106 H HB2  . SER   A 1 74  ? 1.104   -61.029 106.251 1   97.529  ? 768  SER   A HB2  1 c 
ATOM   1107 H HB3  . SER   A 1 74  ? 0.441   -61.907 105.112 1   97.54   ? 768  SER   A HB3  1 c 
ATOM   1108 H HG   . SER   A 1 74  ? 0.271   -59.765 104.679 0   94.74   ? 768  SER   A HG   1 c 
ATOM   1109 N N    . VAL   A 1 75  ? -0.102  -62.572 109.067 1   100.068 ? 769  VAL   A N    1 ? 
ATOM   1110 C CA   . VAL   A 1 75  ? 0.636   -63.351 110.053 1   99.786  ? 769  VAL   A CA   1 ? 
ATOM   1111 C C    . VAL   A 1 75  ? -0.356  -64.056 110.96  1   87.743  ? 769  VAL   A C    1 ? 
ATOM   1112 O O    . VAL   A 1 75  ? -1.324  -63.447 111.376 1   97.294  ? 769  VAL   A O    1 ? 
ATOM   1113 C CB   . VAL   A 1 75  ? 1.58    -62.463 110.883 1   105.944 ? 769  VAL   A CB   1 ? 
ATOM   1114 C CG1  . VAL   A 1 75  ? 2.823   -62.061 110.094 1   109.14  ? 769  VAL   A CG1  1 ? 
ATOM   1115 C CG2  . VAL   A 1 75  ? 0.864   -61.232 111.412 1   113.857 ? 769  VAL   A CG2  1 ? 
ATOM   1116 H H    . VAL   A 1 75  ? -0.682  -61.931 109.36  1   98.679  ? 769  VAL   A H    1 c 
ATOM   1117 H HA   . VAL   A 1 75  ? 1.17    -64.024 109.589 1   98.508  ? 769  VAL   A HA   1 c 
ATOM   1118 H HB   . VAL   A 1 75  ? 1.876   -62.997 111.657 1   106.666 ? 769  VAL   A HB   1 c 
ATOM   1119 H HG11 . VAL   A 1 75  ? 2.558   -61.563 109.302 1   108.19  ? 769  VAL   A HG11 1 c 
ATOM   1120 H HG12 . VAL   A 1 75  ? 3.31    -62.858 109.825 1   108.19  ? 769  VAL   A HG12 1 c 
ATOM   1121 H HG13 . VAL   A 1 75  ? 3.394   -61.504 110.649 1   108.19  ? 769  VAL   A HG13 1 c 
ATOM   1122 H HG21 . VAL   A 1 75  ? 1.433   -60.779 112.057 1   111.289 ? 769  VAL   A HG21 1 c 
ATOM   1123 H HG22 . VAL   A 1 75  ? 0.035   -61.493 111.845 1   111.087 ? 769  VAL   A HG22 1 c 
ATOM   1124 H HG23 . VAL   A 1 75  ? 0.671   -60.629 110.677 1   110.957 ? 769  VAL   A HG23 1 c 
ATOM   1125 N N    . ASP   A 1 76  ? -0.121  -65.339 111.242 1   97.571  ? 770  ASP   A N    1 ? 
ATOM   1126 C CA   . ASP   A 1 76  ? -0.897  -66.052 112.24  1   91.417  ? 770  ASP   A CA   1 ? 
ATOM   1127 C C    . ASP   A 1 76  ? 0.036   -66.871 113.125 1   97.635  ? 770  ASP   A C    1 ? 
ATOM   1128 O O    . ASP   A 1 76  ? 0.551   -67.907 112.713 1   104.246 ? 770  ASP   A O    1 ? 
ATOM   1129 C CB   . ASP   A 1 76  ? -1.934  -66.963 111.622 1   91.642  ? 770  ASP   A CB   1 ? 
ATOM   1130 C CG   . ASP   A 1 76  ? -2.911  -67.471 112.654 1   94.15   ? 770  ASP   A CG   1 ? 
ATOM   1131 O OD1  . ASP   A 1 76  ? -2.889  -66.919 113.761 1   96.932  ? 770  ASP   A OD1  1 ? 
ATOM   1132 O OD2  . ASP   A 1 76  ? -3.651  -68.411 112.345 1   110.484 ? 770  ASP   A OD2  1 ? 
ATOM   1133 H H    . ASP   A 1 76  ? 0.537   -65.786 110.793 1   93.799  ? 770  ASP   A H    1 c 
ATOM   1134 H HA   . ASP   A 1 76  ? -1.362  -65.391 112.8   1   93.831  ? 770  ASP   A HA   1 c 
ATOM   1135 H HB2  . ASP   A 1 76  ? -2.431  -66.468 110.937 1   92.179  ? 770  ASP   A HB2  1 c 
ATOM   1136 H HB3  . ASP   A 1 76  ? -1.498  -67.728 111.192 1   92.254  ? 770  ASP   A HB3  1 c 
ATOM   1137 N N    . ASN   A 1 77  ? 0.264   -66.383 114.346 1   100.829 ? 771  ASN   A N    1 ? 
ATOM   1138 C CA   . ASN   A 1 77  ? 1.151   -67.058 115.272 1   99.99   ? 771  ASN   A CA   1 ? 
ATOM   1139 C C    . ASN   A 1 77  ? 0.788   -66.651 116.683 1   89.297  ? 771  ASN   A C    1 ? 
ATOM   1140 O O    . ASN   A 1 77  ? 0.378   -65.523 116.905 1   103.923 ? 771  ASN   A O    1 ? 
ATOM   1141 C CB   . ASN   A 1 77  ? 2.618   -66.73  115.046 1   111.321 ? 771  ASN   A CB   1 ? 
ATOM   1142 C CG   . ASN   A 1 77  ? 3.531   -67.718 115.724 1   102.294 ? 771  ASN   A CG   1 ? 
ATOM   1143 O OD1  . ASN   A 1 77  ? 4.324   -67.349 116.595 1   82.149  ? 771  ASN   A OD1  1 ? 
ATOM   1144 N ND2  . ASN   A 1 77  ? 3.415   -68.977 115.337 1   111.699 ? 771  ASN   A ND2  1 ? 
ATOM   1145 H H    . ASN   A 1 77  ? -0.141  -65.606 114.607 1   99.679  ? 771  ASN   A H    1 c 
ATOM   1146 H HA   . ASN   A 1 77  ? 1.034   -68.026 115.166 1   99.877  ? 771  ASN   A HA   1 c 
ATOM   1147 H HB2  . ASN   A 1 77  ? 2.803   -66.73  114.086 1   106.444 ? 771  ASN   A HB2  1 c 
ATOM   1148 H HB3  . ASN   A 1 77  ? 2.805   -65.835 115.39  1   106.245 ? 771  ASN   A HB3  1 c 
ATOM   1149 H HD21 . ASN   A 1 77  ? 3.759   -69.626 115.835 1   108.247 ? 771  ASN   A HD21 1 c 
ATOM   1150 H HD22 . ASN   A 1 77  ? 2.998   -69.174 114.579 1   108.506 ? 771  ASN   A HD22 1 c 
ATOM   1151 N N    . PRO   A 1 78  ? 0.833   -67.608 117.629 1   83.15   ? 772  PRO   A N    1 ? 
ATOM   1152 C CA   . PRO   A 1 78  ? 0.582   -67.331 119.033 1   86.986  ? 772  PRO   A CA   1 ? 
ATOM   1153 C C    . PRO   A 1 78  ? 1.44    -66.239 119.652 1   94.499  ? 772  PRO   A C    1 ? 
ATOM   1154 O O    . PRO   A 1 78  ? 1.011   -65.617 120.61  1   96.262  ? 772  PRO   A O    1 ? 
ATOM   1155 C CB   . PRO   A 1 78  ? 0.87    -68.658 119.715 1   86.639  ? 772  PRO   A CB   1 ? 
ATOM   1156 C CG   . PRO   A 1 78  ? 0.476   -69.659 118.646 1   85.469  ? 772  PRO   A CG   1 ? 
ATOM   1157 C CD   . PRO   A 1 78  ? 0.931   -69.049 117.359 1   86.368  ? 772  PRO   A CD   1 ? 
ATOM   1158 H HA   . PRO   A 1 78  ? -0.364  -67.105 119.152 1   87.479  ? 772  PRO   A HA   1 c 
ATOM   1159 H HB2  . PRO   A 1 78  ? 1.816   -68.74  119.945 1   86.496  ? 772  PRO   A HB2  1 c 
ATOM   1160 H HB3  . PRO   A 1 78  ? 0.326   -68.766 120.519 1   86.46   ? 772  PRO   A HB3  1 c 
ATOM   1161 H HG2  . PRO   A 1 78  ? 0.918   -70.519 118.794 1   85.937  ? 772  PRO   A HG2  1 c 
ATOM   1162 H HG3  . PRO   A 1 78  ? -0.492  -69.799 118.638 1   85.937  ? 772  PRO   A HG3  1 c 
ATOM   1163 H HD2  . PRO   A 1 78  ? 1.847   -69.304 117.153 1   85.794  ? 772  PRO   A HD2  1 c 
ATOM   1164 H HD3  . PRO   A 1 78  ? 0.347   -69.308 116.62  1   85.655  ? 772  PRO   A HD3  1 c 
ATOM   1165 N N    . HIS   A 1 79  ? 2.662   -66.049 119.144 1   106.675 ? 773  HIS   A N    1 ? 
ATOM   1166 C CA   . HIS   A 1 79  ? 3.615   -65.136 119.756 1   100.836 ? 773  HIS   A CA   1 ? 
ATOM   1167 C C    . HIS   A 1 79  ? 3.828   -63.918 118.862 1   93.301  ? 773  HIS   A C    1 ? 
ATOM   1168 O O    . HIS   A 1 79  ? 4.777   -63.161 119.04  1   87.059  ? 773  HIS   A O    1 ? 
ATOM   1169 C CB   . HIS   A 1 79  ? 4.902   -65.892 120.1   1   101.991 ? 773  HIS   A CB   1 ? 
ATOM   1170 C CG   . HIS   A 1 79  ? 4.648   -66.992 121.069 1   90.225  ? 773  HIS   A CG   1 ? 
ATOM   1171 N ND1  . HIS   A 1 79  ? 4.677   -68.317 120.7   1   89.406  ? 773  HIS   A ND1  1 ? 
ATOM   1172 C CD2  . HIS   A 1 79  ? 4.33    -66.968 122.361 1   87.852  ? 773  HIS   A CD2  1 ? 
ATOM   1173 C CE1  . HIS   A 1 79  ? 4.391   -69.07  121.745 1   94.808  ? 773  HIS   A CE1  1 ? 
ATOM   1174 N NE2  . HIS   A 1 79  ? 4.179   -68.267 122.768 1   106.845 ? 773  HIS   A NE2  1 ? 
ATOM   1175 H H    . HIS   A 1 79  ? 2.919   -66.516 118.402 1   101.99  ? 773  HIS   A H    1 c 
ATOM   1176 H HA   . HIS   A 1 79  ? 3.226   -64.82  120.608 1   100.51  ? 773  HIS   A HA   1 c 
ATOM   1177 H HB2  . HIS   A 1 79  ? 5.282   -66.268 119.276 1   98.846  ? 773  HIS   A HB2  1 c 
ATOM   1178 H HB3  . HIS   A 1 79  ? 5.548   -65.263 120.488 1   98.782  ? 773  HIS   A HB3  1 c 
ATOM   1179 H HD1  . HIS   A 1 79  ? 4.822   -68.621 119.871 0   90.92   ? 773  HIS   A HD1  1 c 
ATOM   1180 H HD2  . HIS   A 1 79  ? 4.229   -66.209 122.901 1   92.453  ? 773  HIS   A HD2  1 c 
ATOM   1181 H HE1  . HIS   A 1 79  ? 4.356   -70.011 121.76  1   96.096  ? 773  HIS   A HE1  1 c 
ATOM   1182 H HE2  . HIS   A 1 79  ? 3.995   -68.534 123.587 0   107.47  ? 773  HIS   A HE2  1 c 
ATOM   1183 N N    . VAL   A 1 80  ? 2.91    -63.723 117.915 1   108.436 ? 774  VAL   A N    1 ? 
ATOM   1184 C CA   . VAL   A 1 80  ? 2.866   -62.525 117.094 1   99.996  ? 774  VAL   A CA   1 ? 
ATOM   1185 C C    . VAL   A 1 80  ? 1.472   -61.917 117.199 1   91.524  ? 774  VAL   A C    1 ? 
ATOM   1186 O O    . VAL   A 1 80  ? 0.487   -62.648 117.184 1   101.907 ? 774  VAL   A O    1 ? 
ATOM   1187 C CB   . VAL   A 1 80  ? 3.218   -62.864 115.637 1   102.094 ? 774  VAL   A CB   1 ? 
ATOM   1188 C CG1  . VAL   A 1 80  ? 2.649   -61.848 114.668 1   116.74  ? 774  VAL   A CG1  1 ? 
ATOM   1189 C CG2  . VAL   A 1 80  ? 4.717   -63.029 115.45  1   107.251 ? 774  VAL   A CG2  1 ? 
ATOM   1190 H H    . VAL   A 1 80  ? 2.28    -64.367 117.767 1   102.539 ? 774  VAL   A H    1 c 
ATOM   1191 H HA   . VAL   A 1 80  ? 3.518   -61.882 117.435 1   100.174 ? 774  VAL   A HA   1 c 
ATOM   1192 H HB   . VAL   A 1 80  ? 2.796   -63.73  115.434 1   105.29  ? 774  VAL   A HB   1 c 
ATOM   1193 H HG11 . VAL   A 1 80  ? 2.758   -60.955 115.029 1   112.45  ? 774  VAL   A HG11 1 c 
ATOM   1194 H HG12 . VAL   A 1 80  ? 1.704   -62.027 114.525 1   112.12  ? 774  VAL   A HG12 1 c 
ATOM   1195 H HG13 . VAL   A 1 80  ? 3.119   -61.911 113.819 1   112.154 ? 774  VAL   A HG13 1 c 
ATOM   1196 H HG21 . VAL   A 1 80  ? 4.904   -63.28  114.53  1   105.744 ? 774  VAL   A HG21 1 c 
ATOM   1197 H HG22 . VAL   A 1 80  ? 5.044   -63.724 116.046 1   105.711 ? 774  VAL   A HG22 1 c 
ATOM   1198 H HG23 . VAL   A 1 80  ? 5.164   -62.191 115.654 1   105.71  ? 774  VAL   A HG23 1 c 
ATOM   1199 N N    . CYS   A 1 81  ? 1.418   -60.578 117.28  1   94.467  ? 775  CYS   A N    1 ? 
ATOM   1200 C CA   . CYS   A 1 81  ? 0.19    -59.828 117.508 1   108.875 ? 775  CYS   A CA   1 ? 
ATOM   1201 C C    . CYS   A 1 81  ? -0.726  -59.891 116.284 1   118.023 ? 775  CYS   A C    1 ? 
ATOM   1202 O O    . CYS   A 1 81  ? -0.279  -59.742 115.149 1   106.537 ? 775  CYS   A O    1 ? 
ATOM   1203 C CB   . CYS   A 1 81  ? 0.506   -58.379 117.871 1   115.303 ? 775  CYS   A CB   1 ? 
ATOM   1204 S SG   . CYS   A 1 81  ? -0.9    -57.469 118.559 1   135.424 ? 775  CYS   A SG   1 ? 
ATOM   1205 H H    . CYS   A 1 81  ? 2.196   -60.108 117.184 1   97.088  ? 775  CYS   A H    1 c 
ATOM   1206 H HA   . CYS   A 1 81  ? -0.281  -60.245 118.274 1   108.853 ? 775  CYS   A HA   1 c 
ATOM   1207 H HB2  . CYS   A 1 81  ? 1.237   -58.366 118.529 1   117.268 ? 775  CYS   A HB2  1 c 
ATOM   1208 H HB3  . CYS   A 1 81  ? 0.817   -57.908 117.066 1   117.266 ? 775  CYS   A HB3  1 c 
ATOM   1209 N N    . ARG   A 1 82  ? -2.034  -60.04  116.535 1   143.13  ? 776  ARG   A N    1 ? 
ATOM   1210 C CA   . ARG   A 1 82  ? -3.012  -60.269 115.483 1   150.134 ? 776  ARG   A CA   1 ? 
ATOM   1211 C C    . ARG   A 1 82  ? -3.856  -59.01  115.295 1   134.691 ? 776  ARG   A C    1 ? 
ATOM   1212 O O    . ARG   A 1 82  ? -4.289  -58.383 116.272 1   117.365 ? 776  ARG   A O    1 ? 
ATOM   1213 C CB   . ARG   A 1 82  ? -3.888  -61.497 115.764 1   171.313 ? 776  ARG   A CB   1 ? 
ATOM   1214 C CG   . ARG   A 1 82  ? -3.982  -61.947 117.22  1   170.846 ? 776  ARG   A CG   1 ? 
ATOM   1215 C CD   . ARG   A 1 82  ? -5.274  -62.703 117.528 1   154.278 ? 776  ARG   A CD   1 ? 
ATOM   1216 N NE   . ARG   A 1 82  ? -5.106  -64.135 117.802 1   163.255 ? 776  ARG   A NE   1 ? 
ATOM   1217 C CZ   . ARG   A 1 82  ? -4.58   -65.044 116.979 1   162.317 ? 776  ARG   A CZ   1 ? 
ATOM   1218 N NH1  . ARG   A 1 82  ? -4.12   -64.689 115.793 1   164.131 ? 776  ARG   A NH1  1 ? 
ATOM   1219 N NH2  . ARG   A 1 82  ? -4.491  -66.31  117.35  1   149.968 ? 776  ARG   A NH2  1 ? 
ATOM   1220 H H    . ARG   A 1 82  ? -2.327  -59.965 117.397 1   138.094 ? 776  ARG   A H    1 c 
ATOM   1221 H HA   . ARG   A 1 82  ? -2.522  -60.443 114.64  1   148.334 ? 776  ARG   A HA   1 c 
ATOM   1222 H HB2  . ARG   A 1 82  ? -4.794  -61.306 115.439 1   165.798 ? 776  ARG   A HB2  1 c 
ATOM   1223 H HB3  . ARG   A 1 82  ? -3.54   -62.244 115.232 1   166.034 ? 776  ARG   A HB3  1 c 
ATOM   1224 H HG2  . ARG   A 1 82  ? -3.216  -62.525 117.429 1   166.874 ? 776  ARG   A HG2  1 c 
ATOM   1225 H HG3  . ARG   A 1 82  ? -3.935  -61.161 117.804 1   166.334 ? 776  ARG   A HG3  1 c 
ATOM   1226 H HD2  . ARG   A 1 82  ? -5.694  -62.281 118.305 1   159.982 ? 776  ARG   A HD2  1 c 
ATOM   1227 H HD3  . ARG   A 1 82  ? -5.886  -62.595 116.774 1   159.878 ? 776  ARG   A HD3  1 c 
ATOM   1228 H HE   . ARG   A 1 82  ? -5.36   -64.414 118.58  1   158.824 ? 776  ARG   A HE   1 c 
ATOM   1229 H HH11 . ARG   A 1 82  ? -4.671  -64.345 115.194 1   163.591 ? 776  ARG   A HH11 1 c 
ATOM   1230 H HH12 . ARG   A 1 82  ? -3.264  -64.799 115.603 1   163.576 ? 776  ARG   A HH12 1 c 
ATOM   1231 H HH21 . ARG   A 1 82  ? -4.653  -66.539 118.189 1   153.804 ? 776  ARG   A HH21 1 c 
ATOM   1232 H HH22 . ARG   A 1 82  ? -4.268  -66.926 116.756 1   153.769 ? 776  ARG   A HH22 1 c 
ATOM   1233 N N    . LEU   A 1 83  ? -4.078  -58.682 114.016 1   110.839 ? 777  LEU   A N    1 ? 
ATOM   1234 C CA   . LEU   A 1 83  ? -4.971  -57.612 113.608 1   110.171 ? 777  LEU   A CA   1 ? 
ATOM   1235 C C    . LEU   A 1 83  ? -6.35   -58.183 113.333 1   92.438  ? 777  LEU   A C    1 ? 
ATOM   1236 O O    . LEU   A 1 83  ? -6.489  -58.92  112.379 1   88.512  ? 777  LEU   A O    1 ? 
ATOM   1237 C CB   . LEU   A 1 83  ? -4.44   -56.982 112.328 1   112.156 ? 777  LEU   A CB   1 ? 
ATOM   1238 C CG   . LEU   A 1 83  ? -5.418  -56.075 111.575 1   114.367 ? 777  LEU   A CG   1 ? 
ATOM   1239 C CD1  . LEU   A 1 83  ? -5.334  -54.624 112.017 1   116.388 ? 777  LEU   A CD1  1 ? 
ATOM   1240 C CD2  . LEU   A 1 83  ? -5.183  -56.18  110.095 1   121.621 ? 777  LEU   A CD2  1 ? 
ATOM   1241 H H    . LEU   A 1 83  ? -3.649  -59.157 113.364 1   116.36  ? 777  LEU   A H    1 c 
ATOM   1242 H HA   . LEU   A 1 83  ? -5.02   -56.931 114.326 1   107.247 ? 777  LEU   A HA   1 c 
ATOM   1243 H HB2  . LEU   A 1 83  ? -3.644  -56.452 112.559 1   112.178 ? 777  LEU   A HB2  1 c 
ATOM   1244 H HB3  . LEU   A 1 83  ? -4.158  -57.706 111.723 1   112.156 ? 777  LEU   A HB3  1 c 
ATOM   1245 H HG   . LEU   A 1 83  ? -6.338  -56.388 111.759 1   115.657 ? 777  LEU   A HG   1 c 
ATOM   1246 H HD11 . LEU   A 1 83  ? -5.548  -54.559 112.963 1   115.759 ? 777  LEU   A HD11 1 c 
ATOM   1247 H HD12 . LEU   A 1 83  ? -5.966  -54.091 111.506 1   115.668 ? 777  LEU   A HD12 1 c 
ATOM   1248 H HD13 . LEU   A 1 83  ? -4.434  -54.289 111.866 1   115.759 ? 777  LEU   A HD13 1 c 
ATOM   1249 H HD21 . LEU   A 1 83  ? -5.364  -57.088 109.8   1   119.48  ? 777  LEU   A HD21 1 c 
ATOM   1250 H HD22 . LEU   A 1 83  ? -4.259  -55.954 109.896 1   119.468 ? 777  LEU   A HD22 1 c 
ATOM   1251 H HD23 . LEU   A 1 83  ? -5.773  -55.565 109.628 1   119.651 ? 777  LEU   A HD23 1 c 
ATOM   1252 N N    . LEU   A 1 84  ? -7.359  -57.796 114.115 1   91.366  ? 778  LEU   A N    1 ? 
ATOM   1253 C CA   . LEU   A 1 84  ? -8.714  -58.263 113.887 1   98.743  ? 778  LEU   A CA   1 ? 
ATOM   1254 C C    . LEU   A 1 84  ? -9.352  -57.604 112.666 1   104.018 ? 778  LEU   A C    1 ? 
ATOM   1255 O O    . LEU   A 1 84  ? -10.049 -58.274 111.894 1   99.637  ? 778  LEU   A O    1 ? 
ATOM   1256 C CB   . LEU   A 1 84  ? -9.515  -57.981 115.145 1   100.849 ? 778  LEU   A CB   1 ? 
ATOM   1257 C CG   . LEU   A 1 84  ? -9.032  -58.808 116.331 1   113.258 ? 778  LEU   A CG   1 ? 
ATOM   1258 C CD1  . LEU   A 1 84  ? -8.862  -57.941 117.544 1   114.463 ? 778  LEU   A CD1  1 ? 
ATOM   1259 C CD2  . LEU   A 1 84  ? -9.999  -59.939 116.614 1   134.185 ? 778  LEU   A CD2  1 ? 
ATOM   1260 H H    . LEU   A 1 84  ? -7.198  -57.224 114.81  1   93.667  ? 778  LEU   A H    1 c 
ATOM   1261 H HA   . LEU   A 1 84  ? -8.685  -59.243 113.737 1   98.474  ? 778  LEU   A HA   1 c 
ATOM   1262 H HB2  . LEU   A 1 84  ? -9.43   -57.024 115.364 1   103.247 ? 778  LEU   A HB2  1 c 
ATOM   1263 H HB3  . LEU   A 1 84  ? -10.462 -58.19  114.97  1   103.39  ? 778  LEU   A HB3  1 c 
ATOM   1264 H HG   . LEU   A 1 84  ? -8.151  -59.203 116.104 1   114.407 ? 778  LEU   A HG   1 c 
ATOM   1265 H HD11 . LEU   A 1 84  ? -8.245  -57.219 117.342 1   113.886 ? 778  LEU   A HD11 1 c 
ATOM   1266 H HD12 . LEU   A 1 84  ? -8.51   -58.472 118.278 1   114.059 ? 778  LEU   A HD12 1 c 
ATOM   1267 H HD13 . LEU   A 1 84  ? -9.722  -57.57  117.797 1   114.095 ? 778  LEU   A HD13 1 c 
ATOM   1268 H HD21 . LEU   A 1 84  ? -10.35  -60.287 115.777 1   126.95  ? 778  LEU   A HD21 1 c 
ATOM   1269 H HD22 . LEU   A 1 84  ? -10.73  -59.612 117.162 1   127.02  ? 778  LEU   A HD22 1 c 
ATOM   1270 H HD23 . LEU   A 1 84  ? -9.535  -60.649 117.088 1   127.181 ? 778  LEU   A HD23 1 c 
ATOM   1271 N N    . GLY   A 1 85  ? -9.152  -56.291 112.508 1   99.399  ? 779  GLY   A N    1 ? 
ATOM   1272 C CA   . GLY   A 1 85  ? -9.926  -55.558 111.523 1   93.719  ? 779  GLY   A CA   1 ? 
ATOM   1273 C C    . GLY   A 1 85  ? -9.408  -54.15  111.262 1   93.036  ? 779  GLY   A C    1 ? 
ATOM   1274 O O    . GLY   A 1 85  ? -8.578  -53.633 112     1   91.683  ? 779  GLY   A O    1 ? 
ATOM   1275 H H    . GLY   A 1 85  ? -8.536  -55.849 113.018 1   99.064  ? 779  GLY   A H    1 c 
ATOM   1276 H HA2  . GLY   A 1 85  ? -9.929  -56.061 110.677 1   95.514  ? 779  GLY   A HA2  1 c 
ATOM   1277 H HA3  . GLY   A 1 85  ? -10.857 -55.503 111.834 1   95.235  ? 779  GLY   A HA3  1 c 
ATOM   1278 N N    . ILE   A 1 86  ? -9.94   -53.554 110.189 1   105.08  ? 780  ILE   A N    1 ? 
ATOM   1279 C CA   . ILE   A 1 86  ? -9.667  -52.184 109.793 1   101.435 ? 780  ILE   A CA   1 ? 
ATOM   1280 C C    . ILE   A 1 86  ? -10.995 -51.454 109.699 1   94.936  ? 780  ILE   A C    1 ? 
ATOM   1281 O O    . ILE   A 1 86  ? -11.946 -52.002 109.172 1   96.528  ? 780  ILE   A O    1 ? 
ATOM   1282 C CB   . ILE   A 1 86  ? -8.938  -52.136 108.441 1   108.582 ? 780  ILE   A CB   1 ? 
ATOM   1283 C CG1  . ILE   A 1 86  ? -7.534  -52.678 108.558 1   128.244 ? 780  ILE   A CG1  1 ? 
ATOM   1284 C CG2  . ILE   A 1 86  ? -8.928  -50.721 107.871 1   116.786 ? 780  ILE   A CG2  1 ? 
ATOM   1285 C CD1  . ILE   A 1 86  ? -6.615  -51.779 109.327 1   151.372 ? 780  ILE   A CD1  1 ? 
ATOM   1286 H H    . ILE   A 1 86  ? -10.513 -54.041 109.669 1   101.119 ? 780  ILE   A H    1 c 
ATOM   1287 H HA   . ILE   A 1 86  ? -9.115  -51.758 110.473 1   102.549 ? 780  ILE   A HA   1 c 
ATOM   1288 H HB   . ILE   A 1 86  ? -9.427  -52.709 107.818 1   112.161 ? 780  ILE   A HB   1 c 
ATOM   1289 H HG12 . ILE   A 1 86  ? -7.565  -53.552 108.997 1   128.11  ? 780  ILE   A HG12 1 c 
ATOM   1290 H HG13 . ILE   A 1 86  ? -7.17   -52.805 107.658 1   128.166 ? 780  ILE   A HG13 1 c 
ATOM   1291 H HG21 . ILE   A 1 86  ? -8.222  -50.643 107.207 1   114.356 ? 780  ILE   A HG21 1 c 
ATOM   1292 H HG22 . ILE   A 1 86  ? -8.768  -50.081 108.586 1   114.279 ? 780  ILE   A HG22 1 c 
ATOM   1293 H HG23 . ILE   A 1 86  ? -9.784  -50.53  107.453 1   114.21  ? 780  ILE   A HG23 1 c 
ATOM   1294 H HD11 . ILE   A 1 86  ? -6.384  -51.008 108.775 1   143.467 ? 780  ILE   A HD11 1 c 
ATOM   1295 H HD12 . ILE   A 1 86  ? -5.807  -52.273 109.56  1   143.024 ? 780  ILE   A HD12 1 c 
ATOM   1296 H HD13 . ILE   A 1 86  ? -7.064  -51.484 110.139 1   143.072 ? 780  ILE   A HD13 1 c 
ATOM   1297 N N    . CYS   A 1 87  ? -11.042 -50.208 110.163 1   103.677 ? 781  CYS   A N    1 ? 
ATOM   1298 C CA   . CYS   A 1 87  ? -12.238 -49.408 109.991 1   104.915 ? 781  CYS   A CA   1 ? 
ATOM   1299 C C    . CYS   A 1 87  ? -11.923 -48.181 109.142 1   109.226 ? 781  CYS   A C    1 ? 
ATOM   1300 O O    . CYS   A 1 87  ? -11.117 -47.337 109.526 1   103.648 ? 781  CYS   A O    1 ? 
ATOM   1301 C CB   . CYS   A 1 87  ? -12.818 -48.969 111.323 1   105.657 ? 781  CYS   A CB   1 ? 
ATOM   1302 S SG   . CYS   A 1 87  ? -14.549 -48.467 111.164 1   119.855 ? 781  CYS   A SG   1 ? 
ATOM   1303 H H    . CYS   A 1 87  ? -10.32  -49.848 110.593 1   101.795 ? 781  CYS   A H    1 c 
ATOM   1304 H HA   . CYS   A 1 87  ? -12.914 -49.955 109.517 1   105.7   ? 781  CYS   A HA   1 c 
ATOM   1305 H HB2  . CYS   A 1 87  ? -12.759 -49.71  111.966 1   108.1   ? 781  CYS   A HB2  1 c 
ATOM   1306 H HB3  . CYS   A 1 87  ? -12.3   -48.213 111.674 1   108.414 ? 781  CYS   A HB3  1 c 
ATOM   1307 H HG   . CYS   A 1 87  ? -14.727 -48.192 112.323 0   120.67  ? 781  CYS   A HG   1 c 
ATOM   1308 N N    . LEU   A 1 88  ? -12.589 -48.09  107.986 1   121.646 ? 782  LEU   A N    1 ? 
ATOM   1309 C CA   . LEU   A 1 88  ? -12.372 -46.998 107.048 1   125.278 ? 782  LEU   A CA   1 ? 
ATOM   1310 C C    . LEU   A 1 88  ? -13.292 -45.826 107.361 1   133.487 ? 782  LEU   A C    1 ? 
ATOM   1311 O O    . LEU   A 1 88  ? -14.297 -45.61  106.678 1   127.371 ? 782  LEU   A O    1 ? 
ATOM   1312 C CB   . LEU   A 1 88  ? -12.601 -47.491 105.624 1   136.773 ? 782  LEU   A CB   1 ? 
ATOM   1313 C CG   . LEU   A 1 88  ? -11.45  -48.285 105.01  1   134.365 ? 782  LEU   A CG   1 ? 
ATOM   1314 C CD1  . LEU   A 1 88  ? -11.77  -48.606 103.568 1   139.543 ? 782  LEU   A CD1  1 ? 
ATOM   1315 C CD2  . LEU   A 1 88  ? -10.162 -47.499 105.144 1   140.315 ? 782  LEU   A CD2  1 ? 
ATOM   1316 H H    . LEU   A 1 88  ? -13.205 -48.731 107.774 1   119.324 ? 782  LEU   A H    1 c 
ATOM   1317 H HA   . LEU   A 1 88  ? -11.437 -46.689 107.141 1   127.97  ? 782  LEU   A HA   1 c 
ATOM   1318 H HB2  . LEU   A 1 88  ? -13.408 -48.056 105.618 1   133.406 ? 782  LEU   A HB2  1 c 
ATOM   1319 H HB3  . LEU   A 1 88  ? -12.776 -46.709 105.051 1   133.486 ? 782  LEU   A HB3  1 c 
ATOM   1320 H HG   . LEU   A 1 88  ? -11.353 -49.137 105.509 1   136.858 ? 782  LEU   A HG   1 c 
ATOM   1321 H HD11 . LEU   A 1 88  ? -12.441 -49.306 103.535 1   137.973 ? 782  LEU   A HD11 1 c 
ATOM   1322 H HD12 . LEU   A 1 88  ? -10.967 -48.908 103.117 1   137.977 ? 782  LEU   A HD12 1 c 
ATOM   1323 H HD13 . LEU   A 1 88  ? -12.109 -47.81  103.123 1   137.946 ? 782  LEU   A HD13 1 c 
ATOM   1324 H HD21 . LEU   A 1 88  ? -9.797  -47.622 106.036 1   138.427 ? 782  LEU   A HD21 1 c 
ATOM   1325 H HD22 . LEU   A 1 88  ? -10.338 -46.555 104.993 1   138.492 ? 782  LEU   A HD22 1 c 
ATOM   1326 H HD23 . LEU   A 1 88  ? -9.519  -47.816 104.489 1   138.501 ? 782  LEU   A HD23 1 c 
ATOM   1327 N N    . THR   A 1 89  ? -12.94  -45.081 108.416 1   138.517 ? 783  THR   A N    1 ? 
ATOM   1328 C CA   . THR   A 1 89  ? -13.639 -43.852 108.757 1   131.324 ? 783  THR   A CA   1 ? 
ATOM   1329 C C    . THR   A 1 89  ? -12.885 -42.699 108.116 1   130.397 ? 783  THR   A C    1 ? 
ATOM   1330 O O    . THR   A 1 89  ? -12.048 -42.916 107.238 1   127.999 ? 783  THR   A O    1 ? 
ATOM   1331 C CB   . THR   A 1 89  ? -13.788 -43.675 110.271 1   131.311 ? 783  THR   A CB   1 ? 
ATOM   1332 O OG1  . THR   A 1 89  ? -12.569 -44.076 110.897 1   131.45  ? 783  THR   A OG1  1 ? 
ATOM   1333 C CG2  . THR   A 1 89  ? -14.962 -44.477 110.8   1   136.234 ? 783  THR   A CG2  1 ? 
ATOM   1334 H H    . THR   A 1 89  ? -12.238 -45.347 108.939 1   135.371 ? 783  THR   A H    1 c 
ATOM   1335 H HA   . THR   A 1 89  ? -14.539 -43.89  108.365 1   132.511 ? 783  THR   A HA   1 c 
ATOM   1336 H HB   . THR   A 1 89  ? -13.956 -42.727 110.487 1   132.185 ? 783  THR   A HB   1 c 
ATOM   1337 H HG1  . THR   A 1 89  ? -12.394 -44.939 110.7   0   134.28  ? 783  THR   A HG1  1 c 
ATOM   1338 H HG21 . THR   A 1 89  ? -14.874 -44.583 111.761 1   134.913 ? 783  THR   A HG21 1 c 
ATOM   1339 H HG22 . THR   A 1 89  ? -14.973 -45.353 110.378 1   134.776 ? 783  THR   A HG22 1 c 
ATOM   1340 H HG23 . THR   A 1 89  ? -15.792 -44.01  110.599 1   134.793 ? 783  THR   A HG23 1 c 
ATOM   1341 N N    . SER   A 1 90  ? -13.239 -41.483 108.54  1   127.613 ? 784  SER   A N    1 ? 
ATOM   1342 C CA   . SER   A 1 90  ? -12.499 -40.286 108.182 1   132.574 ? 784  SER   A CA   1 ? 
ATOM   1343 C C    . SER   A 1 90  ? -11.018 -40.492 108.498 1   134.917 ? 784  SER   A C    1 ? 
ATOM   1344 O O    . SER   A 1 90  ? -10.152 -40.078 107.73  1   130.743 ? 784  SER   A O    1 ? 
ATOM   1345 C CB   . SER   A 1 90  ? -13.051 -39.074 108.886 1   131.262 ? 784  SER   A CB   1 ? 
ATOM   1346 O OG   . SER   A 1 90  ? -12.125 -38.595 109.851 1   139.343 ? 784  SER   A OG   1 ? 
ATOM   1347 H H    . SER   A 1 90  ? -13.994 -41.392 109.047 1   129.486 ? 784  SER   A H    1 c 
ATOM   1348 H HA   . SER   A 1 90  ? -12.589 -40.149 107.208 1   131.773 ? 784  SER   A HA   1 c 
ATOM   1349 H HB2  . SER   A 1 90  ? -13.231 -38.373 108.232 1   133.428 ? 784  SER   A HB2  1 c 
ATOM   1350 H HB3  . SER   A 1 90  ? -13.89  -39.303 109.327 1   133.372 ? 784  SER   A HB3  1 c 
ATOM   1351 H HG   . SER   A 1 90  ? -12.399 -37.909 110.227 0   138.45  ? 784  SER   A HG   1 c 
ATOM   1352 N N    . THR   A 1 91  ? -10.749 -41.141 109.638 1   140.879 ? 785  THR   A N    1 ? 
ATOM   1353 C CA   . THR   A 1 91  ? -9.416  -41.59  110.009 1   142.342 ? 785  THR   A CA   1 ? 
ATOM   1354 C C    . THR   A 1 91  ? -9.394  -43.112 109.937 1   128.969 ? 785  THR   A C    1 ? 
ATOM   1355 O O    . THR   A 1 91  ? -10.303 -43.758 110.445 1   125.656 ? 785  THR   A O    1 ? 
ATOM   1356 C CB   . THR   A 1 91  ? -9.071  -41.11  111.422 1   155.604 ? 785  THR   A CB   1 ? 
ATOM   1357 O OG1  . THR   A 1 91  ? -10.246 -41.294 112.206 1   140.819 ? 785  THR   A OG1  1 ? 
ATOM   1358 C CG2  . THR   A 1 91  ? -8.686  -39.643 111.476 1   160.962 ? 785  THR   A CG2  1 ? 
ATOM   1359 H H    . THR   A 1 91  ? -11.434 -41.302 110.221 1   139.575 ? 785  THR   A H    1 c 
ATOM   1360 H HA   . THR   A 1 91  ? -8.763  -41.223 109.375 1   141.498 ? 785  THR   A HA   1 c 
ATOM   1361 H HB   . THR   A 1 91  ? -8.338  -41.657 111.794 1   150.962 ? 785  THR   A HB   1 c 
ATOM   1362 H HG1  . THR   A 1 91  ? -10.887 -40.834 111.87  0   140.67  ? 785  THR   A HG1  1 c 
ATOM   1363 H HG21 . THR   A 1 91  ? -8.743  -39.327 112.393 1   159.657 ? 785  THR   A HG21 1 c 
ATOM   1364 H HG22 . THR   A 1 91  ? -9.293  -39.128 110.919 1   159.469 ? 785  THR   A HG22 1 c 
ATOM   1365 H HG23 . THR   A 1 91  ? -7.777  -39.533 111.151 1   159.635 ? 785  THR   A HG23 1 c 
ATOM   1366 N N    . VAL   A 1 92  ? -8.355  -43.671 109.318 1   125.362 ? 786  VAL   A N    1 ? 
ATOM   1367 C CA   . VAL   A 1 92  ? -8.169  -45.115 109.28  1   136.75  ? 786  VAL   A CA   1 ? 
ATOM   1368 C C    . VAL   A 1 92  ? -7.987  -45.607 110.71  1   136.922 ? 786  VAL   A C    1 ? 
ATOM   1369 O O    . VAL   A 1 92  ? -7.178  -45.042 111.432 1   139.517 ? 786  VAL   A O    1 ? 
ATOM   1370 C CB   . VAL   A 1 92  ? -6.938  -45.535 108.457 1   141.123 ? 786  VAL   A CB   1 ? 
ATOM   1371 C CG1  . VAL   A 1 92  ? -7.192  -46.805 107.65  1   150.248 ? 786  VAL   A CG1  1 ? 
ATOM   1372 C CG2  . VAL   A 1 92  ? -6.449  -44.413 107.554 1   145.126 ? 786  VAL   A CG2  1 ? 
ATOM   1373 H H    . VAL   A 1 92  ? -7.733  -43.131 108.925 1   129.365 ? 786  VAL   A H    1 c 
ATOM   1374 H HA   . VAL   A 1 92  ? -8.968  -45.527 108.897 1   135.382 ? 786  VAL   A HA   1 c 
ATOM   1375 H HB   . VAL   A 1 92  ? -6.214  -45.733 109.096 1   142.648 ? 786  VAL   A HB   1 c 
ATOM   1376 H HG11 . VAL   A 1 92  ? -7.905  -46.645 107.01  1   147.428 ? 786  VAL   A HG11 1 c 
ATOM   1377 H HG12 . VAL   A 1 92  ? -7.451  -47.525 108.249 1   147.479 ? 786  VAL   A HG12 1 c 
ATOM   1378 H HG13 . VAL   A 1 92  ? -6.382  -47.056 107.175 1   147.46  ? 786  VAL   A HG13 1 c 
ATOM   1379 H HG21 . VAL   A 1 92  ? -5.801  -44.767 106.922 1   143.873 ? 786  VAL   A HG21 1 c 
ATOM   1380 H HG22 . VAL   A 1 92  ? -6.025  -43.722 108.09  1   143.632 ? 786  VAL   A HG22 1 c 
ATOM   1381 H HG23 . VAL   A 1 92  ? -7.199  -44.034 107.065 1   143.641 ? 786  VAL   A HG23 1 c 
ATOM   1382 N N    . GLN   A 1 93  ? -8.697  -46.676 111.093 1   148.125 ? 787  GLN   A N    1 ? 
ATOM   1383 C CA   . GLN   A 1 93  ? -8.6    -47.235 112.434 1   129.979 ? 787  GLN   A CA   1 ? 
ATOM   1384 C C    . GLN   A 1 93  ? -8.145  -48.688 112.354 1   114.006 ? 787  GLN   A C    1 ? 
ATOM   1385 O O    . GLN   A 1 93  ? -8.676  -49.455 111.555 1   112.865 ? 787  GLN   A O    1 ? 
ATOM   1386 C CB   . GLN   A 1 93  ? -9.937  -47.143 113.165 1   129.487 ? 787  GLN   A CB   1 ? 
ATOM   1387 C CG   . GLN   A 1 93  ? -10.347 -45.712 113.495 1   130.786 ? 787  GLN   A CG   1 ? 
ATOM   1388 C CD   . GLN   A 1 93  ? -11.588 -45.64  114.355 1   135.008 ? 787  GLN   A CD   1 ? 
ATOM   1389 O OE1  . GLN   A 1 93  ? -11.565 -45.117 115.474 1   148.462 ? 787  GLN   A OE1  1 ? 
ATOM   1390 N NE2  . GLN   A 1 93  ? -12.693 -46.167 113.846 1   145.059 ? 787  GLN   A NE2  1 ? 
ATOM   1391 H H    . GLN   A 1 93  ? -9.262  -47.073 110.494 1   141.067 ? 787  GLN   A H    1 c 
ATOM   1392 H HA   . GLN   A 1 93  ? -7.928  -46.717 112.942 1   130.011 ? 787  GLN   A HA   1 c 
ATOM   1393 H HB2  . GLN   A 1 93  ? -10.628 -47.552 112.608 1   129.736 ? 787  GLN   A HB2  1 c 
ATOM   1394 H HB3  . GLN   A 1 93  ? -9.88   -47.658 113.996 1   129.773 ? 787  GLN   A HB3  1 c 
ATOM   1395 H HG2  . GLN   A 1 93  ? -9.616  -45.27  113.963 1   131.799 ? 787  GLN   A HG2  1 c 
ATOM   1396 H HG3  . GLN   A 1 93  ? -10.51  -45.221 112.662 1   131.485 ? 787  GLN   A HG3  1 c 
ATOM   1397 H HE21 . GLN   A 1 93  ? -13.438 -46.169 114.327 1   141.618 ? 787  GLN   A HE21 1 c 
ATOM   1398 H HE22 . GLN   A 1 93  ? -12.692 -46.504 113.027 1   141.253 ? 787  GLN   A HE22 1 c 
ATOM   1399 N N    . LEU   A 1 94  ? -7.145  -49.03  113.173 1   113.66  ? 788  LEU   A N    1 ? 
ATOM   1400 C CA   . LEU   A 1 94  ? -6.637  -50.387 113.285 1   113.099 ? 788  LEU   A CA   1 ? 
ATOM   1401 C C    . LEU   A 1 94  ? -7.162  -51.023 114.564 1   104.91  ? 788  LEU   A C    1 ? 
ATOM   1402 O O    . LEU   A 1 94  ? -6.877  -50.531 115.646 1   119.852 ? 788  LEU   A O    1 ? 
ATOM   1403 C CB   . LEU   A 1 94  ? -5.111  -50.36  113.278 1   116.205 ? 788  LEU   A CB   1 ? 
ATOM   1404 C CG   . LEU   A 1 94  ? -4.472  -50.847 111.976 1   128.716 ? 788  LEU   A CG   1 ? 
ATOM   1405 C CD1  . LEU   A 1 94  ? -5.089  -50.106 110.791 1   145.782 ? 788  LEU   A CD1  1 ? 
ATOM   1406 C CD2  . LEU   A 1 94  ? -2.958  -50.773 111.981 1   144.063 ? 788  LEU   A CD2  1 ? 
ATOM   1407 H H    . LEU   A 1 94  ? -6.764  -48.382 113.694 1   113.898 ? 788  LEU   A H    1 c 
ATOM   1408 H HA   . LEU   A 1 94  ? -6.961  -50.915 112.514 1   112.461 ? 788  LEU   A HA   1 c 
ATOM   1409 H HB2  . LEU   A 1 94  ? -4.813  -49.437 113.447 1   118.295 ? 788  LEU   A HB2  1 c 
ATOM   1410 H HB3  . LEU   A 1 94  ? -4.785  -50.926 114.016 1   118.144 ? 788  LEU   A HB3  1 c 
ATOM   1411 H HG   . LEU   A 1 94  ? -4.71   -51.804 111.871 1   131.953 ? 788  LEU   A HG   1 c 
ATOM   1412 H HD11 . LEU   A 1 94  ? -6.05   -50.205 110.803 1   140.17  ? 788  LEU   A HD11 1 c 
ATOM   1413 H HD12 . LEU   A 1 94  ? -4.728  -50.461 109.963 1   140.302 ? 788  LEU   A HD12 1 c 
ATOM   1414 H HD13 . LEU   A 1 94  ? -4.867  -49.162 110.854 1   140.412 ? 788  LEU   A HD13 1 c 
ATOM   1415 H HD21 . LEU   A 1 94  ? -2.596  -51.588 112.368 1   139.506 ? 788  LEU   A HD21 1 c 
ATOM   1416 H HD22 . LEU   A 1 94  ? -2.672  -50.013 112.512 1   139.732 ? 788  LEU   A HD22 1 c 
ATOM   1417 H HD23 . LEU   A 1 94  ? -2.632  -50.678 111.071 1   139.822 ? 788  LEU   A HD23 1 c 
ATOM   1418 N N    . ILE   A 1 95  ? -7.908  -52.119 114.427 1   97.332  ? 789  ILE   A N    1 ? 
ATOM   1419 C CA   . ILE   A 1 95  ? -8.391  -52.851 115.579 1   100.632 ? 789  ILE   A CA   1 ? 
ATOM   1420 C C    . ILE   A 1 95  ? -7.514  -54.082 115.779 1   99.389  ? 789  ILE   A C    1 ? 
ATOM   1421 O O    . ILE   A 1 95  ? -7.448  -54.944 114.911 1   86.666  ? 789  ILE   A O    1 ? 
ATOM   1422 C CB   . ILE   A 1 95  ? -9.878  -53.205 115.422 1   106.987 ? 789  ILE   A CB   1 ? 
ATOM   1423 C CG1  . ILE   A 1 95  ? -10.73  -51.949 115.394 1   113.407 ? 789  ILE   A CG1  1 ? 
ATOM   1424 C CG2  . ILE   A 1 95  ? -10.339 -54.152 116.53  1   121.054 ? 789  ILE   A CG2  1 ? 
ATOM   1425 C CD1  . ILE   A 1 95  ? -10.991 -51.398 114.009 1   118.947 ? 789  ILE   A CD1  1 ? 
ATOM   1426 H H    . ILE   A 1 95  ? -8.124  -52.419 113.591 1   100.025 ? 789  ILE   A H    1 c 
ATOM   1427 H HA   . ILE   A 1 95  ? -8.302  -52.279 116.365 1   101.058 ? 789  ILE   A HA   1 c 
ATOM   1428 H HB   . ILE   A 1 95  ? -9.989  -53.664 114.565 1   109.525 ? 789  ILE   A HB   1 c 
ATOM   1429 H HG12 . ILE   A 1 95  ? -11.591 -52.144 115.818 1   113.177 ? 789  ILE   A HG12 1 c 
ATOM   1430 H HG13 . ILE   A 1 95  ? -10.288 -51.257 115.927 1   112.984 ? 789  ILE   A HG13 1 c 
ATOM   1431 H HG21 . ILE   A 1 95  ? -11.291 -54.324 116.437 1   116.614 ? 789  ILE   A HG21 1 c 
ATOM   1432 H HG22 . ILE   A 1 95  ? -10.169 -53.745 117.394 1   116.484 ? 789  ILE   A HG22 1 c 
ATOM   1433 H HG23 . ILE   A 1 95  ? -9.855  -54.992 116.469 1   116.48  ? 789  ILE   A HG23 1 c 
ATOM   1434 H HD11 . ILE   A 1 95  ? -10.159 -51.06  113.628 1   117.139 ? 789  ILE   A HD11 1 c 
ATOM   1435 H HD12 . ILE   A 1 95  ? -11.638 -50.668 114.068 1   117.232 ? 789  ILE   A HD12 1 c 
ATOM   1436 H HD13 . ILE   A 1 95  ? -11.348 -52.099 113.433 1   117.185 ? 789  ILE   A HD13 1 c 
ATOM   1437 N N    . THR   A 1 96  ? -6.865  -54.148 116.949 1   99.519  ? 790  THR   A N    1 ? 
ATOM   1438 C CA   . THR   A 1 96  ? -5.915  -55.196 117.271 1   93.868  ? 790  THR   A CA   1 ? 
ATOM   1439 C C    . THR   A 1 96  ? -6.323  -55.81  118.607 1   89.843  ? 790  THR   A C    1 ? 
ATOM   1440 O O    . THR   A 1 96  ? -7.084  -55.219 119.369 1   93.332  ? 790  THR   A O    1 ? 
ATOM   1441 C CB   . THR   A 1 96  ? -4.493  -54.63  117.312 1   106.913 ? 790  THR   A CB   1 ? 
ATOM   1442 O OG1  . THR   A 1 96  ? -4.46   -53.652 118.343 1   137.14  ? 790  THR   A OG1  1 ? 
ATOM   1443 C CG2  . THR   A 1 96  ? -4.06   -53.902 116.051 1   109.61  ? 790  THR   A CG2  1 ? 
ATOM   1444 H H    . THR   A 1 96  ? -7.027  -53.505 117.578 1   98.163  ? 790  THR   A H    1 c 
ATOM   1445 H HA   . THR   A 1 96  ? -5.959  -55.889 116.576 1   96.409  ? 790  THR   A HA   1 c 
ATOM   1446 H HB   . THR   A 1 96  ? -3.852  -55.352 117.514 1   110.542 ? 790  THR   A HB   1 c 
ATOM   1447 H HG1  . THR   A 1 96  ? -5.051  -53.022 118.172 0   136.17  ? 790  THR   A HG1  1 c 
ATOM   1448 H HG21 . THR   A 1 96  ? -3.154  -53.571 116.162 1   109.182 ? 790  THR   A HG21 1 c 
ATOM   1449 H HG22 . THR   A 1 96  ? -4.658  -53.153 115.888 1   108.927 ? 790  THR   A HG22 1 c 
ATOM   1450 H HG23 . THR   A 1 96  ? -4.094  -54.511 115.296 1   109.322 ? 790  THR   A HG23 1 c 
ATOM   1451 N N    . GLN   A 1 97  ? -5.837  -57.026 118.857 1   100.21  ? 791  GLN   A N    1 ? 
ATOM   1452 C CA   . GLN   A 1 97  ? -6.052  -57.701 120.124 1   98.311  ? 791  GLN   A CA   1 ? 
ATOM   1453 C C    . GLN   A 1 97  ? -5.41   -56.903 121.256 1   96.95   ? 791  GLN   A C    1 ? 
ATOM   1454 O O    . GLN   A 1 97  ? -4.303  -56.387 121.105 1   92.703  ? 791  GLN   A O    1 ? 
ATOM   1455 C CB   . GLN   A 1 97  ? -5.464  -59.107 120.043 1   113.207 ? 791  GLN   A CB   1 ? 
ATOM   1456 C CG   . GLN   A 1 97  ? -5.369  -59.824 121.386 1   115.451 ? 791  GLN   A CG   1 ? 
ATOM   1457 C CD   . GLN   A 1 97  ? -4.695  -61.172 121.263 1   116.919 ? 791  GLN   A CD   1 ? 
ATOM   1458 O OE1  . GLN   A 1 97  ? -3.788  -61.367 120.443 1   125.817 ? 791  GLN   A OE1  1 ? 
ATOM   1459 N NE2  . GLN   A 1 97  ? -5.167  -62.134 122.041 1   104.218 ? 791  GLN   A NE2  1 ? 
ATOM   1460 H H    . GLN   A 1 97  ? -5.353  -57.452 118.209 1   97.383  ? 791  GLN   A H    1 c 
ATOM   1461 H HA   . GLN   A 1 97  ? -7.028  -57.764 120.283 1   100.923 ? 791  GLN   A HA   1 c 
ATOM   1462 H HB2  . GLN   A 1 97  ? -6.016  -59.642 119.435 1   110.086 ? 791  GLN   A HB2  1 c 
ATOM   1463 H HB3  . GLN   A 1 97  ? -4.567  -59.046 119.653 1   110.082 ? 791  GLN   A HB3  1 c 
ATOM   1464 H HG2  . GLN   A 1 97  ? -4.859  -59.274 122.018 1   115.139 ? 791  GLN   A HG2  1 c 
ATOM   1465 H HG3  . GLN   A 1 97  ? -6.27   -59.948 121.754 1   115.134 ? 791  GLN   A HG3  1 c 
ATOM   1466 H HE21 . GLN   A 1 97  ? -4.614  -62.592 122.563 1   107.918 ? 791  GLN   A HE21 1 c 
ATOM   1467 H HE22 . GLN   A 1 97  ? -6.034  -62.319 122.036 1   108.074 ? 791  GLN   A HE22 1 c 
ATOM   1468 N N    . LEU   A 1 98  ? -6.136  -56.84  122.38  1   99.026  ? 792  LEU   A N    1 ? 
ATOM   1469 C CA   . LEU   A 1 98  ? -5.755  -56.078 123.561 1   100.85  ? 792  LEU   A CA   1 ? 
ATOM   1470 C C    . LEU   A 1 98  ? -4.706  -56.874 124.316 1   94.451  ? 792  LEU   A C    1 ? 
ATOM   1471 O O    . LEU   A 1 98  ? -4.992  -57.999 124.693 1   97.784  ? 792  LEU   A O    1 ? 
ATOM   1472 C CB   . LEU   A 1 98  ? -6.974  -55.891 124.47  1   104.731 ? 792  LEU   A CB   1 ? 
ATOM   1473 C CG   . LEU   A 1 98  ? -7.043  -54.657 125.382 1   97.961  ? 792  LEU   A CG   1 ? 
ATOM   1474 C CD1  . LEU   A 1 98  ? -7.569  -55.077 126.743 1   98.301  ? 792  LEU   A CD1  1 ? 
ATOM   1475 C CD2  . LEU   A 1 98  ? -5.76   -53.882 125.552 1   101.223 ? 792  LEU   A CD2  1 ? 
ATOM   1476 H H    . LEU   A 1 98  ? -6.918  -57.312 122.411 1   99.014  ? 792  LEU   A H    1 c 
ATOM   1477 H HA   . LEU   A 1 98  ? -5.392  -55.201 123.283 1   99.867  ? 792  LEU   A HA   1 c 
ATOM   1478 H HB2  . LEU   A 1 98  ? -7.773  -55.881 123.897 1   102.142 ? 792  LEU   A HB2  1 c 
ATOM   1479 H HB3  . LEU   A 1 98  ? -7.06   -56.694 125.034 1   102.122 ? 792  LEU   A HB3  1 c 
ATOM   1480 H HG   . LEU   A 1 98  ? -7.71   -54.035 124.991 1   99.85   ? 792  LEU   A HG   1 c 
ATOM   1481 H HD11 . LEU   A 1 98  ? -8.415  -55.542 126.635 1   98.141  ? 792  LEU   A HD11 1 c 
ATOM   1482 H HD12 . LEU   A 1 98  ? -7.701  -54.289 127.297 1   98.197  ? 792  LEU   A HD12 1 c 
ATOM   1483 H HD13 . LEU   A 1 98  ? -6.927  -55.668 127.171 1   98.181  ? 792  LEU   A HD13 1 c 
ATOM   1484 H HD21 . LEU   A 1 98  ? -5.51   -53.476 124.705 1   100.224 ? 792  LEU   A HD21 1 c 
ATOM   1485 H HD22 . LEU   A 1 98  ? -5.054  -54.48  125.845 1   100.184 ? 792  LEU   A HD22 1 c 
ATOM   1486 H HD23 . LEU   A 1 98  ? -5.888  -53.184 126.216 1   100.204 ? 792  LEU   A HD23 1 c 
ATOM   1487 N N    . MET   A 1 99  ? -3.53   -56.283 124.539 1   95.37   ? 793  MET   A N    1 ? 
ATOM   1488 C CA   . MET   A 1 99  ? -2.544  -56.867 125.424 1   92.293  ? 793  MET   A CA   1 ? 
ATOM   1489 C C    . MET   A 1 99  ? -2.651  -56.14  126.753 1   86.355  ? 793  MET   A C    1 ? 
ATOM   1490 O O    . MET   A 1 99  ? -2.135  -55.047 126.924 1   88.993  ? 793  MET   A O    1 ? 
ATOM   1491 C CB   . MET   A 1 99  ? -1.142  -56.777 124.831 1   104.745 ? 793  MET   A CB   1 ? 
ATOM   1492 C CG   . MET   A 1 99  ? -1.067  -57.288 123.395 1   104.199 ? 793  MET   A CG   1 ? 
ATOM   1493 S SD   . MET   A 1 99  ? -1.617  -58.987 123.132 1   92.57   ? 793  MET   A SD   1 ? 
ATOM   1494 C CE   . MET   A 1 99  ? -0.053  -59.765 123.571 1   114.276 ? 793  MET   A CE   1 ? 
ATOM   1495 H H    . MET   A 1 99  ? -3.34   -55.489 124.13  1   94.657  ? 793  MET   A H    1 c 
ATOM   1496 H HA   . MET   A 1 99  ? -2.768  -57.819 125.561 1   93.985  ? 793  MET   A HA   1 c 
ATOM   1497 H HB2  . MET   A 1 99  ? -0.847  -55.841 124.852 1   101.476 ? 793  MET   A HB2  1 c 
ATOM   1498 H HB3  . MET   A 1 99  ? -0.528  -57.299 125.39  1   101.607 ? 793  MET   A HB3  1 c 
ATOM   1499 H HG2  . MET   A 1 99  ? -1.607  -56.705 122.827 1   102.219 ? 793  MET   A HG2  1 c 
ATOM   1500 H HG3  . MET   A 1 99  ? -0.145  -57.219 123.086 1   102.336 ? 793  MET   A HG3  1 c 
ATOM   1501 H HE1  . MET   A 1 99  ? -0.148  -60.734 123.534 1   107.963 ? 793  MET   A HE1  1 c 
ATOM   1502 H HE2  . MET   A 1 99  ? 0.637   -59.475 122.947 1   107.975 ? 793  MET   A HE2  1 c 
ATOM   1503 H HE3  . MET   A 1 99  ? 0.2     -59.496 124.473 1   107.998 ? 793  MET   A HE3  1 c 
ATOM   1504 N N    . PRO   A 1 100 ? -3.454  -56.703 127.672 1   93.607  ? 794  PRO   A N    1 ? 
ATOM   1505 C CA   . PRO   A 1 100 ? -3.841  -56.042 128.907 1   91.474  ? 794  PRO   A CA   1 ? 
ATOM   1506 C C    . PRO   A 1 100 ? -2.696  -55.538 129.779 1   90.759  ? 794  PRO   A C    1 ? 
ATOM   1507 O O    . PRO   A 1 100 ? -2.855  -54.53  130.446 1   104.261 ? 794  PRO   A O    1 ? 
ATOM   1508 C CB   . PRO   A 1 100 ? -4.631  -57.132 129.626 1   93.473  ? 794  PRO   A CB   1 ? 
ATOM   1509 C CG   . PRO   A 1 100 ? -5.213  -57.958 128.506 1   91.138  ? 794  PRO   A CG   1 ? 
ATOM   1510 C CD   . PRO   A 1 100 ? -4.136  -57.99  127.487 1   99.35   ? 794  PRO   A CD   1 ? 
ATOM   1511 H HA   . PRO   A 1 100 ? -4.44   -55.296 128.698 1   92.504  ? 794  PRO   A HA   1 c 
ATOM   1512 H HB2  . PRO   A 1 100 ? -4.046  -57.673 130.192 1   92.477  ? 794  PRO   A HB2  1 c 
ATOM   1513 H HB3  . PRO   A 1 100 ? -5.338  -56.744 130.178 1   92.485  ? 794  PRO   A HB3  1 c 
ATOM   1514 H HG2  . PRO   A 1 100 ? -5.429  -58.862 128.811 1   93.508  ? 794  PRO   A HG2  1 c 
ATOM   1515 H HG3  . PRO   A 1 100 ? -6.02   -57.542 128.145 1   93.534  ? 794  PRO   A HG3  1 c 
ATOM   1516 H HD2  . PRO   A 1 100 ? -3.524  -58.731 127.643 1   95.95   ? 794  PRO   A HD2  1 c 
ATOM   1517 H HD3  . PRO   A 1 100 ? -4.509  -58.064 126.599 1   96.004  ? 794  PRO   A HD3  1 c 
ATOM   1518 N N    . PHE   A 1 101 ? -1.563  -56.242 129.803 1   95.054  ? 795  PHE   A N    1 ? 
ATOM   1519 C CA   . PHE   A 1 101 ? -0.5    -55.925 130.743 1   94.71   ? 795  PHE   A CA   1 ? 
ATOM   1520 C C    . PHE   A 1 101 ? 0.543   -55.012 130.102 1   100.872 ? 795  PHE   A C    1 ? 
ATOM   1521 O O    . PHE   A 1 101 ? 1.555   -54.688 130.731 1   101.646 ? 795  PHE   A O    1 ? 
ATOM   1522 C CB   . PHE   A 1 101 ? 0.127   -57.217 131.239 1   103.694 ? 795  PHE   A CB   1 ? 
ATOM   1523 C CG   . PHE   A 1 101 ? -0.804  -58.052 132.088 1   94.483  ? 795  PHE   A CG   1 ? 
ATOM   1524 C CD1  . PHE   A 1 101 ? -1.67   -58.957 131.502 1   89.813  ? 795  PHE   A CD1  1 ? 
ATOM   1525 C CD2  . PHE   A 1 101 ? -0.809  -57.917 133.465 1   105.735 ? 795  PHE   A CD2  1 ? 
ATOM   1526 C CE1  . PHE   A 1 101 ? -2.51   -59.724 132.285 1   94.297  ? 795  PHE   A CE1  1 ? 
ATOM   1527 C CE2  . PHE   A 1 101 ? -1.63   -58.708 134.246 1   112.642 ? 795  PHE   A CE2  1 ? 
ATOM   1528 C CZ   . PHE   A 1 101 ? -2.495  -59.595 133.653 1   106.775 ? 795  PHE   A CZ   1 ? 
ATOM   1529 H H    . PHE   A 1 101 ? -1.45   -56.942 129.226 1   94.024  ? 795  PHE   A H    1 c 
ATOM   1530 H HA   . PHE   A 1 101 ? -0.896  -55.453 131.523 1   97.485  ? 795  PHE   A HA   1 c 
ATOM   1531 H HB2  . PHE   A 1 101 ? 0.388   -57.741 130.461 1   99.323  ? 795  PHE   A HB2  1 c 
ATOM   1532 H HB3  . PHE   A 1 101 ? 0.934   -57.003 131.758 1   99.445  ? 795  PHE   A HB3  1 c 
ATOM   1533 H HD1  . PHE   A 1 101 ? -1.683  -59.051 130.564 1   92.257  ? 795  PHE   A HD1  1 c 
ATOM   1534 H HD2  . PHE   A 1 101 ? -0.209  -57.315 133.877 1   104.416 ? 795  PHE   A HD2  1 c 
ATOM   1535 H HE1  . PHE   A 1 101 ? -3.097  -60.34  131.878 1   96.162  ? 795  PHE   A HE1  1 c 
ATOM   1536 H HE2  . PHE   A 1 101 ? -1.627  -58.606 135.184 1   109.255 ? 795  PHE   A HE2  1 c 
ATOM   1537 H HZ   . PHE   A 1 101 ? -3.072  -60.12  134.185 1   104.844 ? 795  PHE   A HZ   1 c 
ATOM   1538 N N    . GLY   A 1 102 ? 0.279   -54.599 128.856 1   101.642 ? 796  GLY   A N    1 ? 
ATOM   1539 C CA   . GLY   A 1 102 ? 1.053   -53.567 128.192 1   99.853  ? 796  GLY   A CA   1 ? 
ATOM   1540 C C    . GLY   A 1 102 ? 2.397   -54.063 127.662 1   100.745 ? 796  GLY   A C    1 ? 
ATOM   1541 O O    . GLY   A 1 102 ? 2.568   -55.222 127.295 1   91.857  ? 796  GLY   A O    1 ? 
ATOM   1542 H H    . GLY   A 1 102 ? -0.406  -54.987 128.394 1   100.836 ? 796  GLY   A H    1 c 
ATOM   1543 H HA2  . GLY   A 1 102 ? 0.524   -53.211 127.441 1   100.736 ? 796  GLY   A HA2  1 c 
ATOM   1544 H HA3  . GLY   A 1 102 ? 1.205   -52.829 128.827 1   100.658 ? 796  GLY   A HA3  1 c 
ATOM   1545 N N    . CYS   A 1 103 ? 3.311   -53.094 127.599 1   113.815 ? 797  CYS   A N    1 ? 
ATOM   1546 C CA   . CYS   A 1 103 ? 4.688   -53.187 127.159 1   102.16  ? 797  CYS   A CA   1 ? 
ATOM   1547 C C    . CYS   A 1 103 ? 5.484   -54.15  128.04  1   107.901 ? 797  CYS   A C    1 ? 
ATOM   1548 O O    . CYS   A 1 103 ? 5.42    -54.06  129.265 1   114.627 ? 797  CYS   A O    1 ? 
ATOM   1549 C CB   . CYS   A 1 103 ? 5.237   -51.782 127.348 1   104.877 ? 797  CYS   A CB   1 ? 
ATOM   1550 S SG   . CYS   A 1 103 ? 6.742   -51.458 126.428 1   120.316 ? 797  CYS   A SG   1 ? 
ATOM   1551 H H    . CYS   A 1 103 ? 3.028   -52.269 127.87  1   107.688 ? 797  CYS   A H    1 c 
ATOM   1552 H HA   . CYS   A 1 103 ? 4.717   -53.484 126.216 1   106.147 ? 797  CYS   A HA   1 c 
ATOM   1553 H HB2  . CYS   A 1 103 ? 4.559   -51.13  127.065 1   107.072 ? 797  CYS   A HB2  1 c 
ATOM   1554 H HB3  . CYS   A 1 103 ? 5.418   -51.633 128.301 1   107.095 ? 797  CYS   A HB3  1 c 
ATOM   1555 H HG   . CYS   A 1 103 ? 6.883   -50.3   126.814 0   121.53  ? 797  CYS   A HG   1 c 
ATOM   1556 N N    . LEU   A 1 104 ? 6.258   -55.052 127.427 1   104.167 ? 798  LEU   A N    1 ? 
ATOM   1557 C CA   . LEU   A 1 104 ? 7.101   -55.956 128.188 1   93.248  ? 798  LEU   A CA   1 ? 
ATOM   1558 C C    . LEU   A 1 104 ? 8.214   -55.187 128.888 1   88.132  ? 798  LEU   A C    1 ? 
ATOM   1559 O O    . LEU   A 1 104 ? 8.61    -55.563 129.978 1   96.568  ? 798  LEU   A O    1 ? 
ATOM   1560 C CB   . LEU   A 1 104 ? 7.703   -57.05  127.317 1   97.401  ? 798  LEU   A CB   1 ? 
ATOM   1561 C CG   . LEU   A 1 104 ? 8.534   -58.096 128.071 1   96.179  ? 798  LEU   A CG   1 ? 
ATOM   1562 C CD1  . LEU   A 1 104 ? 7.739   -58.7   129.2   1   99.004  ? 798  LEU   A CD1  1 ? 
ATOM   1563 C CD2  . LEU   A 1 104 ? 8.994   -59.203 127.154 1   103.552 ? 798  LEU   A CD2  1 ? 
ATOM   1564 H H    . LEU   A 1 104 ? 6.261   -55.104 126.514 1   102.445 ? 798  LEU   A H    1 c 
ATOM   1565 H HA   . LEU   A 1 104 ? 6.536   -56.377 128.884 1   95.241  ? 798  LEU   A HA   1 c 
ATOM   1566 H HB2  . LEU   A 1 104 ? 6.968   -57.511 126.85  1   96.158  ? 798  LEU   A HB2  1 c 
ATOM   1567 H HB3  . LEU   A 1 104 ? 8.277   -56.624 126.639 1   96.158  ? 798  LEU   A HB3  1 c 
ATOM   1568 H HG   . LEU   A 1 104 ? 9.335   -57.652 128.451 1   98.215  ? 798  LEU   A HG   1 c 
ATOM   1569 H HD11 . LEU   A 1 104 ? 7.673   -58.062 129.93  1   98.11   ? 798  LEU   A HD11 1 c 
ATOM   1570 H HD12 . LEU   A 1 104 ? 8.183   -59.505 129.516 1   98.193  ? 798  LEU   A HD12 1 c 
ATOM   1571 H HD13 . LEU   A 1 104 ? 6.848   -58.926 128.885 1   98.149  ? 798  LEU   A HD13 1 c 
ATOM   1572 H HD21 . LEU   A 1 104 ? 9.521   -58.826 126.43  1   101.295 ? 798  LEU   A HD21 1 c 
ATOM   1573 H HD22 . LEU   A 1 104 ? 8.221   -59.662 126.786 1   101.295 ? 798  LEU   A HD22 1 c 
ATOM   1574 H HD23 . LEU   A 1 104 ? 9.538   -59.835 127.654 1   101.278 ? 798  LEU   A HD23 1 c 
ATOM   1575 N N    . LEU   A 1 105 ? 8.736   -54.139 128.251 1   93.861  ? 799  LEU   A N    1 ? 
ATOM   1576 C CA   . LEU   A 1 105 ? 9.771   -53.303 128.846 1   98.709  ? 799  LEU   A CA   1 ? 
ATOM   1577 C C    . LEU   A 1 105 ? 9.262   -52.62  130.114 1   100.594 ? 799  LEU   A C    1 ? 
ATOM   1578 O O    . LEU   A 1 105 ? 9.961   -52.58  131.114 1   104.796 ? 799  LEU   A O    1 ? 
ATOM   1579 C CB   . LEU   A 1 105 ? 10.214  -52.25  127.838 1   106.775 ? 799  LEU   A CB   1 ? 
ATOM   1580 C CG   . LEU   A 1 105 ? 11.19   -51.199 128.368 1   103.961 ? 799  LEU   A CG   1 ? 
ATOM   1581 C CD1  . LEU   A 1 105 ? 12.585  -51.774 128.45  1   103.438 ? 799  LEU   A CD1  1 ? 
ATOM   1582 C CD2  . LEU   A 1 105 ? 11.156  -49.964 127.483 1   109.882 ? 799  LEU   A CD2  1 ? 
ATOM   1583 H H    . LEU   A 1 105 ? 8.444   -53.939 127.408 1   93.747  ? 799  LEU   A H    1 c 
ATOM   1584 H HA   . LEU   A 1 105 ? 10.543  -53.879 129.08  1   99.479  ? 799  LEU   A HA   1 c 
ATOM   1585 H HB2  . LEU   A 1 105 ? 10.635  -52.711 127.076 1   104.223 ? 799  LEU   A HB2  1 c 
ATOM   1586 H HB3  . LEU   A 1 105 ? 9.411   -51.788 127.504 1   104.28  ? 799  LEU   A HB3  1 c 
ATOM   1587 H HG   . LEU   A 1 105 ? 10.907  -50.933 129.279 1   105.423 ? 799  LEU   A HG   1 c 
ATOM   1588 H HD11 . LEU   A 1 105 ? 12.583  -52.55  129.035 1   103.594 ? 799  LEU   A HD11 1 c 
ATOM   1589 H HD12 . LEU   A 1 105 ? 13.192  -51.103 128.806 1   103.594 ? 799  LEU   A HD12 1 c 
ATOM   1590 H HD13 . LEU   A 1 105 ? 12.881  -52.038 127.563 1   103.597 ? 799  LEU   A HD13 1 c 
ATOM   1591 H HD21 . LEU   A 1 105 ? 10.278  -49.551 127.535 1   108.077 ? 799  LEU   A HD21 1 c 
ATOM   1592 H HD22 . LEU   A 1 105 ? 11.338  -50.219 126.562 1   108.097 ? 799  LEU   A HD22 1 c 
ATOM   1593 H HD23 . LEU   A 1 105 ? 11.83   -49.331 127.781 1   108.115 ? 799  LEU   A HD23 1 c 
ATOM   1594 N N    . ASP   A 1 106 ? 8.058   -52.04  130.042 1   106.06  ? 800  ASP   A N    1 ? 
ATOM   1595 C CA   . ASP   A 1 106 ? 7.445   -51.404 131.196 1   107.655 ? 800  ASP   A CA   1 ? 
ATOM   1596 C C    . ASP   A 1 106 ? 7.239   -52.431 132.297 1   103.781 ? 800  ASP   A C    1 ? 
ATOM   1597 O O    . ASP   A 1 106 ? 7.505   -52.154 133.457 1   115.08  ? 800  ASP   A O    1 ? 
ATOM   1598 C CB   . ASP   A 1 106 ? 6.111   -50.778 130.849 1   110.71  ? 800  ASP   A CB   1 ? 
ATOM   1599 C CG   . ASP   A 1 106 ? 6.229   -49.502 130.041 1   107.445 ? 800  ASP   A CG   1 ? 
ATOM   1600 O OD1  . ASP   A 1 106 ? 7.355   -49.159 129.652 1   118.493 ? 800  ASP   A OD1  1 ? 
ATOM   1601 O OD2  . ASP   A 1 106 ? 5.199   -48.854 129.846 1   122.747 ? 800  ASP   A OD2  1 ? 
ATOM   1602 H H    . ASP   A 1 106 ? 7.608   -52.037 129.246 1   105.03  ? 800  ASP   A H    1 c 
ATOM   1603 H HA   . ASP   A 1 106 ? 8.052   -50.704 131.526 1   107.222 ? 800  ASP   A HA   1 c 
ATOM   1604 H HB2  . ASP   A 1 106 ? 5.572   -51.424 130.35  1   109.2   ? 800  ASP   A HB2  1 c 
ATOM   1605 H HB3  . ASP   A 1 106 ? 5.635   -50.566 131.679 1   109.207 ? 800  ASP   A HB3  1 c 
ATOM   1606 N N    . TYR   A 1 107 ? 6.813   -53.628 131.893 1   100.197 ? 801  TYR   A N    1 ? 
ATOM   1607 C CA   . TYR   A 1 107 ? 6.441   -54.674 132.824 1   98.756  ? 801  TYR   A CA   1 ? 
ATOM   1608 C C    . TYR   A 1 107 ? 7.626   -55.158 133.658 1   95.517  ? 801  TYR   A C    1 ? 
ATOM   1609 O O    . TYR   A 1 107 ? 7.461   -55.391 134.849 1   102.535 ? 801  TYR   A O    1 ? 
ATOM   1610 C CB   . TYR   A 1 107 ? 5.848   -55.838 132.037 1   98.634  ? 801  TYR   A CB   1 ? 
ATOM   1611 C CG   . TYR   A 1 107 ? 5.14    -56.845 132.924 1   97.421  ? 801  TYR   A CG   1 ? 
ATOM   1612 C CD1  . TYR   A 1 107 ? 3.846   -56.615 133.36  1   102.725 ? 801  TYR   A CD1  1 ? 
ATOM   1613 C CD2  . TYR   A 1 107 ? 5.763   -58.019 133.314 1   98.662  ? 801  TYR   A CD2  1 ? 
ATOM   1614 C CE1  . TYR   A 1 107 ? 3.191   -57.53  134.161 1   111.453 ? 801  TYR   A CE1  1 ? 
ATOM   1615 C CE2  . TYR   A 1 107 ? 5.122   -58.945 134.114 1   98.503  ? 801  TYR   A CE2  1 ? 
ATOM   1616 C CZ   . TYR   A 1 107 ? 3.829   -58.695 134.543 1   111.652 ? 801  TYR   A CZ   1 ? 
ATOM   1617 O OH   . TYR   A 1 107 ? 3.15    -59.576 135.336 1   123.398 ? 801  TYR   A OH   1 ? 
ATOM   1618 H H    . TYR   A 1 107 ? 6.745   -53.797 130.997 1   100.691 ? 801  TYR   A H    1 c 
ATOM   1619 H HA   . TYR   A 1 107 ? 5.744   -54.318 133.437 1   98.437  ? 801  TYR   A HA   1 c 
ATOM   1620 H HB2  . TYR   A 1 107 ? 5.206   -55.483 131.383 1   98.479  ? 801  TYR   A HB2  1 c 
ATOM   1621 H HB3  . TYR   A 1 107 ? 6.57    -56.291 131.548 1   98.379  ? 801  TYR   A HB3  1 c 
ATOM   1622 H HD1  . TYR   A 1 107 ? 3.403   -55.821 133.104 1   103.448 ? 801  TYR   A HD1  1 c 
ATOM   1623 H HD2  . TYR   A 1 107 ? 6.645   -58.193 133.024 1   98.55   ? 801  TYR   A HD2  1 c 
ATOM   1624 H HE1  . TYR   A 1 107 ? 2.311   -57.359 134.452 1   109.246 ? 801  TYR   A HE1  1 c 
ATOM   1625 H HE2  . TYR   A 1 107 ? 5.561   -59.737 134.372 1   101.586 ? 801  TYR   A HE2  1 c 
ATOM   1626 H HH   . TYR   A 1 107 ? 2.385   -59.286 135.491 0   122.86  ? 801  TYR   A HH   1 c 
ATOM   1627 N N    . VAL   A 1 108 ? 8.79    -55.367 133.036 1   90.806  ? 802  VAL   A N    1 ? 
ATOM   1628 C CA   . VAL   A 1 108 ? 9.96    -55.841 133.757 1   91.305  ? 802  VAL   A CA   1 ? 
ATOM   1629 C C    . VAL   A 1 108 ? 10.424  -54.78  134.74  1   94.875  ? 802  VAL   A C    1 ? 
ATOM   1630 O O    . VAL   A 1 108 ? 10.832  -55.128 135.843 1   113.375 ? 802  VAL   A O    1 ? 
ATOM   1631 C CB   . VAL   A 1 108 ? 11.138  -56.257 132.865 1   96.413  ? 802  VAL   A CB   1 ? 
ATOM   1632 C CG1  . VAL   A 1 108 ? 10.811  -57.534 132.12  1   104.063 ? 802  VAL   A CG1  1 ? 
ATOM   1633 C CG2  . VAL   A 1 108 ? 11.539  -55.161 131.888 1   111.935 ? 802  VAL   A CG2  1 ? 
ATOM   1634 H H    . VAL   A 1 108 ? 8.85    -55.224 132.135 1   92.346  ? 802  VAL   A H    1 c 
ATOM   1635 H HA   . VAL   A 1 108 ? 9.691   -56.619 134.267 1   93.338  ? 802  VAL   A HA   1 c 
ATOM   1636 H HB   . VAL   A 1 108 ? 11.906  -56.437 133.457 1   99.512  ? 802  VAL   A HB   1 c 
ATOM   1637 H HG11 . VAL   A 1 108 ? 10.009  -57.403 131.586 1   101.734 ? 802  VAL   A HG11 1 c 
ATOM   1638 H HG12 . VAL   A 1 108 ? 10.662  -58.253 132.756 1   101.778 ? 802  VAL   A HG12 1 c 
ATOM   1639 H HG13 . VAL   A 1 108 ? 11.553  -57.768 131.536 1   101.697 ? 802  VAL   A HG13 1 c 
ATOM   1640 H HG21 . VAL   A 1 108 ? 12.3    -55.461 131.363 1   106.992 ? 802  VAL   A HG21 1 c 
ATOM   1641 H HG22 . VAL   A 1 108 ? 11.784  -54.359 132.377 1   106.887 ? 802  VAL   A HG22 1 c 
ATOM   1642 H HG23 . VAL   A 1 108 ? 10.798  -54.966 131.294 1   106.767 ? 802  VAL   A HG23 1 c 
ATOM   1643 N N    . ARG   A 1 109 ? 10.366  -53.51  134.33  1   100.992 ? 803  ARG   A N    1 ? 
ATOM   1644 C CA   . ARG   A 1 109 ? 10.82   -52.408 135.167 1   106.53  ? 803  ARG   A CA   1 ? 
ATOM   1645 C C    . ARG   A 1 109 ? 9.932   -52.308 136.401 1   100.652 ? 803  ARG   A C    1 ? 
ATOM   1646 O O    . ARG   A 1 109 ? 10.426  -52.185 137.52  1   110.599 ? 803  ARG   A O    1 ? 
ATOM   1647 C CB   . ARG   A 1 109 ? 10.747  -51.066 134.433 1   100.583 ? 803  ARG   A CB   1 ? 
ATOM   1648 C CG   . ARG   A 1 109 ? 11.543  -51.078 133.142 1   98.829  ? 803  ARG   A CG   1 ? 
ATOM   1649 C CD   . ARG   A 1 109 ? 11.543  -49.726 132.495 1   95.358  ? 803  ARG   A CD   1 ? 
ATOM   1650 N NE   . ARG   A 1 109 ? 12.803  -49.512 131.778 1   94.875  ? 803  ARG   A NE   1 ? 
ATOM   1651 C CZ   . ARG   A 1 109 ? 12.956  -48.664 130.773 1   99.044  ? 803  ARG   A CZ   1 ? 
ATOM   1652 N NH1  . ARG   A 1 109 ? 11.923  -47.966 130.349 1   116.943 ? 803  ARG   A NH1  1 ? 
ATOM   1653 N NH2  . ARG   A 1 109 ? 14.129  -48.519 130.179 1   103.408 ? 803  ARG   A NH2  1 ? 
ATOM   1654 H H    . ARG   A 1 109 ? 10.019  -53.322 133.506 1   100.63  ? 803  ARG   A H    1 c 
ATOM   1655 H HA   . ARG   A 1 109 ? 11.753  -52.586 135.45  1   103.263 ? 803  ARG   A HA   1 c 
ATOM   1656 H HB2  . ARG   A 1 109 ? 9.81    -50.858 134.23  1   101.484 ? 803  ARG   A HB2  1 c 
ATOM   1657 H HB3  . ARG   A 1 109 ? 11.095  -50.36  135.018 1   101.449 ? 803  ARG   A HB3  1 c 
ATOM   1658 H HG2  . ARG   A 1 109 ? 12.466  -51.343 133.338 1   98.403  ? 803  ARG   A HG2  1 c 
ATOM   1659 H HG3  . ARG   A 1 109 ? 11.16   -51.731 132.523 1   98.486  ? 803  ARG   A HG3  1 c 
ATOM   1660 H HD2  . ARG   A 1 109 ? 10.795  -49.666 131.867 1   96.247  ? 803  ARG   A HD2  1 c 
ATOM   1661 H HD3  . ARG   A 1 109 ? 11.432  -49.028 133.173 1   96.123  ? 803  ARG   A HD3  1 c 
ATOM   1662 H HE   . ARG   A 1 109 ? 13.501  -49.965 132.031 1   96.103  ? 803  ARG   A HE   1 c 
ATOM   1663 H HH11 . ARG   A 1 109 ? 11.403  -47.548 130.931 1   110.855 ? 803  ARG   A HH11 1 c 
ATOM   1664 H HH12 . ARG   A 1 109 ? 11.758  -47.909 129.483 1   111.015 ? 803  ARG   A HH12 1 c 
ATOM   1665 H HH21 . ARG   A 1 109 ? 14.818  -49.011 130.433 1   101.961 ? 803  ARG   A HH21 1 c 
ATOM   1666 H HH22 . ARG   A 1 109 ? 14.22   -47.928 129.527 1   102.125 ? 803  ARG   A HH22 1 c 
ATOM   1667 N N    . GLU   A 1 110 ? 8.621   -52.379 136.164 1   103.79  ? 804  GLU   A N    1 ? 
ATOM   1668 C CA   . GLU   A 1 110 ? 7.625   -52.203 137.204 1   106.371 ? 804  GLU   A CA   1 ? 
ATOM   1669 C C    . GLU   A 1 110 ? 7.615   -53.384 138.161 1   100.195 ? 804  GLU   A C    1 ? 
ATOM   1670 O O    . GLU   A 1 110 ? 7.438   -53.175 139.349 1   121.774 ? 804  GLU   A O    1 ? 
ATOM   1671 C CB   . GLU   A 1 110 ? 6.253   -52.056 136.555 1   124.138 ? 804  GLU   A CB   1 ? 
ATOM   1672 C CG   . GLU   A 1 110 ? 5.174   -51.509 137.479 1   130.018 ? 804  GLU   A CG   1 ? 
ATOM   1673 C CD   . GLU   A 1 110 ? 3.981   -51.032 136.665 1   146.324 ? 804  GLU   A CD   1 ? 
ATOM   1674 O OE1  . GLU   A 1 110 ? 2.844   -51.042 137.194 1   173.256 ? 804  GLU   A OE1  1 ? 
ATOM   1675 O OE2  . GLU   A 1 110 ? 4.189   -50.627 135.495 1   142.749 ? 804  GLU   A OE2  1 ? 
ATOM   1676 H H    . GLU   A 1 110 ? 8.334   -52.542 135.312 1   103.868 ? 804  GLU   A H    1 c 
ATOM   1677 H HA   . GLU   A 1 110 ? 7.839   -51.379 137.711 1   107.737 ? 804  GLU   A HA   1 c 
ATOM   1678 H HB2  . GLU   A 1 110 ? 6.342   -51.46  135.783 1   121.046 ? 804  GLU   A HB2  1 c 
ATOM   1679 H HB3  . GLU   A 1 110 ? 5.967   -52.932 136.222 1   120.951 ? 804  GLU   A HB3  1 c 
ATOM   1680 H HG2  . GLU   A 1 110 ? 4.882   -52.211 138.099 1   132.174 ? 804  GLU   A HG2  1 c 
ATOM   1681 H HG3  . GLU   A 1 110 ? 5.531   -50.758 137.998 1   132.178 ? 804  GLU   A HG3  1 c 
ATOM   1682 N N    . HIS   A 1 111 ? 7.796   -54.605 137.644 1   117.765 ? 805  HIS   A N    1 ? 
ATOM   1683 C CA   . HIS   A 1 111 ? 7.64    -55.814 138.445 1   118.088 ? 805  HIS   A CA   1 ? 
ATOM   1684 C C    . HIS   A 1 111 ? 8.964   -56.528 138.723 1   110.652 ? 805  HIS   A C    1 ? 
ATOM   1685 O O    . HIS   A 1 111 ? 8.939   -57.705 139.082 1   117.874 ? 805  HIS   A O    1 ? 
ATOM   1686 C CB   . HIS   A 1 111 ? 6.714   -56.806 137.737 1   123.436 ? 805  HIS   A CB   1 ? 
ATOM   1687 C CG   . HIS   A 1 111 ? 5.303   -56.347 137.667 1   119.74  ? 805  HIS   A CG   1 ? 
ATOM   1688 N ND1  . HIS   A 1 111 ? 4.865   -55.374 136.794 1   117.612 ? 805  HIS   A ND1  1 ? 
ATOM   1689 C CD2  . HIS   A 1 111 ? 4.239   -56.747 138.352 1   117.483 ? 805  HIS   A CD2  1 ? 
ATOM   1690 C CE1  . HIS   A 1 111 ? 3.569   -55.192 136.962 1   118.779 ? 805  HIS   A CE1  1 ? 
ATOM   1691 N NE2  . HIS   A 1 111 ? 3.169   -56.019 137.9   1   124.895 ? 805  HIS   A NE2  1 ? 
ATOM   1692 H H    . HIS   A 1 111 ? 8.021   -54.69  136.762 1   113.249 ? 805  HIS   A H    1 c 
ATOM   1693 H HA   . HIS   A 1 111 ? 7.233   -55.57  139.312 1   117.489 ? 805  HIS   A HA   1 c 
ATOM   1694 H HB2  . HIS   A 1 111 ? 7.048   -56.956 136.826 1   121.137 ? 805  HIS   A HB2  1 c 
ATOM   1695 H HB3  . HIS   A 1 111 ? 6.742   -57.664 138.213 1   121.223 ? 805  HIS   A HB3  1 c 
ATOM   1696 H HD1  . HIS   A 1 111 ? 5.38    -54.961 136.211 0   117.45  ? 805  HIS   A HD1  1 c 
ATOM   1697 H HD2  . HIS   A 1 111 ? 4.215   -57.404 139.02  1   119.651 ? 805  HIS   A HD2  1 c 
ATOM   1698 H HE1  . HIS   A 1 111 ? 3.027   -54.581 136.491 1   119.9   ? 805  HIS   A HE1  1 c 
ATOM   1699 H HE2  . HIS   A 1 111 ? 2.37    -56.134 138.232 0   124.56  ? 805  HIS   A HE2  1 c 
ATOM   1700 N N    . LYS   A 1 112 ? 10.097  -55.833 138.581 1   113.81  ? 806  LYS   A N    1 ? 
ATOM   1701 C CA   . LYS   A 1 112 ? 11.413  -56.459 138.638 1   123.283 ? 806  LYS   A CA   1 ? 
ATOM   1702 C C    . LYS   A 1 112 ? 11.551  -57.272 139.919 1   128.415 ? 806  LYS   A C    1 ? 
ATOM   1703 O O    . LYS   A 1 112 ? 12.198  -58.316 139.921 1   150.877 ? 806  LYS   A O    1 ? 
ATOM   1704 C CB   . LYS   A 1 112 ? 12.554  -55.44  138.576 1   126.807 ? 806  LYS   A CB   1 ? 
ATOM   1705 C CG   . LYS   A 1 112 ? 12.357  -54.21  139.427 1   132.137 ? 806  LYS   A CG   1 ? 
ATOM   1706 C CD   . LYS   A 1 112 ? 13.645  -53.407 139.539 1   135.067 ? 806  LYS   A CD   1 ? 
ATOM   1707 C CE   . LYS   A 1 112 ? 13.92   -52.523 138.358 1   141.391 ? 806  LYS   A CE   1 ? 
ATOM   1708 N NZ   . LYS   A 1 112 ? 13.656  -51.111 138.66  1   143.415 ? 806  LYS   A NZ   1 ? 
ATOM   1709 H H    . LYS   A 1 112 ? 10.047  -54.932 138.436 1   115.367 ? 806  LYS   A H    1 c 
ATOM   1710 H HA   . LYS   A 1 112 ? 11.496  -57.074 137.865 1   122.913 ? 806  LYS   A HA   1 c 
ATOM   1711 H HB2  . LYS   A 1 112 ? 13.385  -55.881 138.856 1   127.255 ? 806  LYS   A HB2  1 c 
ATOM   1712 H HB3  . LYS   A 1 112 ? 12.67   -55.155 137.645 1   126.925 ? 806  LYS   A HB3  1 c 
ATOM   1713 H HG2  . LYS   A 1 112 ? 11.659  -53.65  139.027 1   131.218 ? 806  LYS   A HG2  1 c 
ATOM   1714 H HG3  . LYS   A 1 112 ? 12.063  -54.48  140.323 1   131.43  ? 806  LYS   A HG3  1 c 
ATOM   1715 H HD2  . LYS   A 1 112 ? 13.598  -52.852 140.347 1   135.89  ? 806  LYS   A HD2  1 c 
ATOM   1716 H HD3  . LYS   A 1 112 ? 14.397  -54.028 139.652 1   135.726 ? 806  LYS   A HD3  1 c 
ATOM   1717 H HE2  . LYS   A 1 112 ? 14.852  -52.619 138.093 1   140.371 ? 806  LYS   A HE2  1 c 
ATOM   1718 H HE3  . LYS   A 1 112 ? 13.363  -52.795 137.607 1   140.285 ? 806  LYS   A HE3  1 c 
ATOM   1719 H HZ1  . LYS   A 1 112 ? 14.244  -50.815 139.283 1   142.731 ? 806  LYS   A HZ1  1 c 
ATOM   1720 H HZ2  . LYS   A 1 112 ? 12.813  -51.017 138.978 1   142.732 ? 806  LYS   A HZ2  1 c 
ATOM   1721 H HZ3  . LYS   A 1 112 ? 13.747  -50.615 137.907 1   142.767 ? 806  LYS   A HZ3  1 c 
ATOM   1722 N N    . ASP   A 1 113 ? 10.955  -56.769 141.006 1   129.62  ? 807  ASP   A N    1 ? 
ATOM   1723 C CA   . ASP   A 1 113 ? 11.03   -57.416 142.302 1   121.697 ? 807  ASP   A CA   1 ? 
ATOM   1724 C C    . ASP   A 1 113 ? 10.282  -58.743 142.279 1   105.066 ? 807  ASP   A C    1 ? 
ATOM   1725 O O    . ASP   A 1 113 ? 10.65   -59.65  143.007 1   118.996 ? 807  ASP   A O    1 ? 
ATOM   1726 C CB   . ASP   A 1 113 ? 10.606  -56.463 143.403 1   130.41  ? 807  ASP   A CB   1 ? 
ATOM   1727 C CG   . ASP   A 1 113 ? 11.579  -55.309 143.613 1   127.738 ? 807  ASP   A CG   1 ? 
ATOM   1728 O OD1  . ASP   A 1 113 ? 12.795  -55.56  143.541 1   120.772 ? 807  ASP   A OD1  1 ? 
ATOM   1729 O OD2  . ASP   A 1 113 ? 11.122  -54.168 143.835 1   138.252 ? 807  ASP   A OD2  1 ? 
ATOM   1730 H H    . ASP   A 1 113 ? 10.492  -55.984 140.938 1   127.314 ? 807  ASP   A H    1 c 
ATOM   1731 H HA   . ASP   A 1 113 ? 11.976  -57.62  142.475 1   121.635 ? 807  ASP   A HA   1 c 
ATOM   1732 H HB2  . ASP   A 1 113 ? 9.725   -56.092 143.185 1   127.819 ? 807  ASP   A HB2  1 c 
ATOM   1733 H HB3  . ASP   A 1 113 ? 10.528  -56.96  144.244 1   127.771 ? 807  ASP   A HB3  1 c 
ATOM   1734 N N    . ASN   A 1 114 ? 9.276   -58.9   141.419 1   108.706 ? 808  ASN   A N    1 ? 
ATOM   1735 C CA   . ASN   A 1 114 ? 8.499   -60.133 141.44  1   124.723 ? 808  ASN   A CA   1 ? 
ATOM   1736 C C    . ASN   A 1 114 ? 8.705   -61.043 140.217 1   111.438 ? 808  ASN   A C    1 ? 
ATOM   1737 O O    . ASN   A 1 114 ? 8.012   -62.052 140.101 1   106.998 ? 808  ASN   A O    1 ? 
ATOM   1738 C CB   . ASN   A 1 114 ? 7.016   -59.838 141.654 1   136.495 ? 808  ASN   A CB   1 ? 
ATOM   1739 C CG   . ASN   A 1 114 ? 6.484   -60.651 142.805 1   139.782 ? 808  ASN   A CG   1 ? 
ATOM   1740 O OD1  . ASN   A 1 114 ? 5.789   -61.657 142.615 1   140.732 ? 808  ASN   A OD1  1 ? 
ATOM   1741 N ND2  . ASN   A 1 114 ? 6.869   -60.268 144.011 1   149.943 ? 808  ASN   A ND2  1 ? 
ATOM   1742 H H    . ASN   A 1 114 ? 9.056   -58.239 140.828 1   111.462 ? 808  ASN   A H    1 c 
ATOM   1743 H HA   . ASN   A 1 114 ? 8.795   -60.649 142.223 1   121.077 ? 808  ASN   A HA   1 c 
ATOM   1744 H HB2  . ASN   A 1 114 ? 6.896   -58.886 141.845 1   134.231 ? 808  ASN   A HB2  1 c 
ATOM   1745 H HB3  . ASN   A 1 114 ? 6.515   -60.054 140.842 1   134.122 ? 808  ASN   A HB3  1 c 
ATOM   1746 H HD21 . ASN   A 1 114 ? 6.568   -60.695 144.727 1   146.673 ? 808  ASN   A HD21 1 c 
ATOM   1747 H HD22 . ASN   A 1 114 ? 7.427   -59.584 144.103 1   146.65  ? 808  ASN   A HD22 1 c 
ATOM   1748 N N    . ILE   A 1 115 ? 9.674   -60.767 139.337 1   112.25  ? 809  ILE   A N    1 ? 
ATOM   1749 C CA   . ILE   A 1 115 ? 9.823   -61.559 138.117 1   104.418 ? 809  ILE   A CA   1 ? 
ATOM   1750 C C    . ILE   A 1 115 ? 10.864  -62.668 138.295 1   97.853  ? 809  ILE   A C    1 ? 
ATOM   1751 O O    . ILE   A 1 115 ? 12.062  -62.395 138.42  1   90.299  ? 809  ILE   A O    1 ? 
ATOM   1752 C CB   . ILE   A 1 115 ? 10.199  -60.678 136.914 1   108.57  ? 809  ILE   A CB   1 ? 
ATOM   1753 C CG1  . ILE   A 1 115 ? 9.108   -59.675 136.604 1   108.257 ? 809  ILE   A CG1  1 ? 
ATOM   1754 C CG2  . ILE   A 1 115 ? 10.526  -61.546 135.697 1   116.134 ? 809  ILE   A CG2  1 ? 
ATOM   1755 C CD1  . ILE   A 1 115 ? 9.519   -58.628 135.596 1   111.137 ? 809  ILE   A CD1  1 ? 
ATOM   1756 H H    . ILE   A 1 115 ? 10.255  -60.079 139.495 1   110.246 ? 809  ILE   A H    1 c 
ATOM   1757 H HA   . ILE   A 1 115 ? 8.962   -61.976 137.919 1   105.308 ? 809  ILE   A HA   1 c 
ATOM   1758 H HB   . ILE   A 1 115 ? 11.003  -60.177 137.152 1   109.028 ? 809  ILE   A HB   1 c 
ATOM   1759 H HG12 . ILE   A 1 115 ? 8.328   -60.155 136.258 1   109.092 ? 809  ILE   A HG12 1 c 
ATOM   1760 H HG13 . ILE   A 1 115 ? 8.841   -59.229 137.431 1   109.081 ? 809  ILE   A HG13 1 c 
ATOM   1761 H HG21 . ILE   A 1 115 ? 10.659  -60.981 134.918 1   113.743 ? 809  ILE   A HG21 1 c 
ATOM   1762 H HG22 . ILE   A 1 115 ? 9.792   -62.16  135.529 1   113.774 ? 809  ILE   A HG22 1 c 
ATOM   1763 H HG23 . ILE   A 1 115 ? 11.338  -62.053 135.865 1   113.534 ? 809  ILE   A HG23 1 c 
ATOM   1764 H HD11 . ILE   A 1 115 ? 10.37   -58.229 135.861 1   110.122 ? 809  ILE   A HD11 1 c 
ATOM   1765 H HD12 . ILE   A 1 115 ? 8.831   -57.937 135.568 1   110.141 ? 809  ILE   A HD12 1 c 
ATOM   1766 H HD13 . ILE   A 1 115 ? 9.611   -59.029 134.711 1   110.216 ? 809  ILE   A HD13 1 c 
ATOM   1767 N N    . GLY   A 1 116 ? 10.399  -63.92  138.2   1   95.474  ? 810  GLY   A N    1 ? 
ATOM   1768 C CA   . GLY   A 1 116 ? 11.247  -65.087 138.386 1   99.857  ? 810  GLY   A CA   1 ? 
ATOM   1769 C C    . GLY   A 1 116 ? 11.967  -65.504 137.106 1   93.768  ? 810  GLY   A C    1 ? 
ATOM   1770 O O    . GLY   A 1 116 ? 11.58   -65.125 136.011 1   103.044 ? 810  GLY   A O    1 ? 
ATOM   1771 H H    . GLY   A 1 116 ? 9.515   -64.052 138.01  1   97.137  ? 810  GLY   A H    1 c 
ATOM   1772 H HA2  . GLY   A 1 116 ? 11.914  -64.89  139.086 1   97.408  ? 810  GLY   A HA2  1 c 
ATOM   1773 H HA3  . GLY   A 1 116 ? 10.691  -65.836 138.704 1   97.414  ? 810  GLY   A HA3  1 c 
ATOM   1774 N N    . SER   A 1 117 ? 12.999  -66.335 137.263 1   104.335 ? 811  SER   A N    1 ? 
ATOM   1775 C CA   . SER   A 1 117 ? 13.796  -66.85  136.156 1   104.479 ? 811  SER   A CA   1 ? 
ATOM   1776 C C    . SER   A 1 117 ? 12.963  -67.645 135.149 1   94.116  ? 811  SER   A C    1 ? 
ATOM   1777 O O    . SER   A 1 117 ? 13.237  -67.589 133.958 1   109.341 ? 811  SER   A O    1 ? 
ATOM   1778 C CB   . SER   A 1 117 ? 14.937  -67.701 136.66  1   105.835 ? 811  SER   A CB   1 ? 
ATOM   1779 O OG   . SER   A 1 117 ? 14.472  -68.817 137.397 1   108.709 ? 811  SER   A OG   1 ? 
ATOM   1780 H H    . SER   A 1 117 ? 13.22   -66.596 138.111 1   101.722 ? 811  SER   A H    1 c 
ATOM   1781 H HA   . SER   A 1 117 ? 14.184  -66.073 135.679 1   102.714 ? 811  SER   A HA   1 c 
ATOM   1782 H HB2  . SER   A 1 117 ? 15.46   -68.016 135.9   1   106.042 ? 811  SER   A HB2  1 c 
ATOM   1783 H HB3  . SER   A 1 117 ? 15.518  -67.158 137.225 1   106.171 ? 811  SER   A HB3  1 c 
ATOM   1784 H HG   . SER   A 1 117 ? 15.13   -69.266 137.667 0   109.48  ? 811  SER   A HG   1 c 
ATOM   1785 N N    . GLN   A 1 118 ? 11.981  -68.411 135.628 1   100.567 ? 812  GLN   A N    1 ? 
ATOM   1786 C CA   . GLN   A 1 118 ? 11.149  -69.235 134.767 1   97.545  ? 812  GLN   A CA   1 ? 
ATOM   1787 C C    . GLN   A 1 118 ? 10.372  -68.353 133.791 1   93.837  ? 812  GLN   A C    1 ? 
ATOM   1788 O O    . GLN   A 1 118 ? 10.187  -68.713 132.633 1   94.085  ? 812  GLN   A O    1 ? 
ATOM   1789 C CB   . GLN   A 1 118 ? 10.18   -70.086 135.586 1   97.35   ? 812  GLN   A CB   1 ? 
ATOM   1790 C CG   . GLN   A 1 118 ? 9.364   -71.061 134.748 1   102.83  ? 812  GLN   A CG   1 ? 
ATOM   1791 C CD   . GLN   A 1 118 ? 10.004  -72.427 134.655 1   109.349 ? 812  GLN   A CD   1 ? 
ATOM   1792 O OE1  . GLN   A 1 118 ? 9.903   -73.231 135.584 1   124.345 ? 812  GLN   A OE1  1 ? 
ATOM   1793 N NE2  . GLN   A 1 118 ? 10.665  -72.711 133.543 1   115.675 ? 812  GLN   A NE2  1 ? 
ATOM   1794 H H    . GLN   A 1 118 ? 11.825  -68.425 136.529 1   98.383  ? 812  GLN   A H    1 c 
ATOM   1795 H HA   . GLN   A 1 118 ? 11.741  -69.836 134.247 1   97.455  ? 812  GLN   A HA   1 c 
ATOM   1796 H HB2  . GLN   A 1 118 ? 10.691  -70.589 136.254 1   98.73   ? 812  GLN   A HB2  1 c 
ATOM   1797 H HB3  . GLN   A 1 118 ? 9.568   -69.491 136.067 1   98.909  ? 812  GLN   A HB3  1 c 
ATOM   1798 H HG2  . GLN   A 1 118 ? 8.472   -71.159 135.144 1   103.009 ? 812  GLN   A HG2  1 c 
ATOM   1799 H HG3  . GLN   A 1 118 ? 9.25    -70.703 133.844 1   103.014 ? 812  GLN   A HG3  1 c 
ATOM   1800 H HE21 . GLN   A 1 118 ? 10.871  -73.554 133.357 1   113.725 ? 812  GLN   A HE21 1 c 
ATOM   1801 H HE22 . GLN   A 1 118 ? 10.903  -72.061 132.987 1   113.531 ? 812  GLN   A HE22 1 c 
ATOM   1802 N N    . TYR   A 1 119 ? 9.896   -67.205 134.269 1   93.463  ? 813  TYR   A N    1 ? 
ATOM   1803 C CA   . TYR   A 1 119 ? 9.19    -66.264 133.414 1   94.687  ? 813  TYR   A CA   1 ? 
ATOM   1804 C C    . TYR   A 1 119 ? 10.118  -65.698 132.347 1   88.724  ? 813  TYR   A C    1 ? 
ATOM   1805 O O    . TYR   A 1 119 ? 9.762   -65.644 131.177 1   92.583  ? 813  TYR   A O    1 ? 
ATOM   1806 C CB   . TYR   A 1 119 ? 8.602   -65.123 134.245 1   101.517 ? 813  TYR   A CB   1 ? 
ATOM   1807 C CG   . TYR   A 1 119 ? 7.205   -65.462 134.723 1   105.762 ? 813  TYR   A CG   1 ? 
ATOM   1808 C CD1  . TYR   A 1 119 ? 6.167   -65.481 133.815 1   115.552 ? 813  TYR   A CD1  1 ? 
ATOM   1809 C CD2  . TYR   A 1 119 ? 6.932   -65.79  136.045 1   107.077 ? 813  TYR   A CD2  1 ? 
ATOM   1810 C CE1  . TYR   A 1 119 ? 4.884   -65.809 134.207 1   121.131 ? 813  TYR   A CE1  1 ? 
ATOM   1811 C CE2  . TYR   A 1 119 ? 5.653   -66.119 136.453 1   101.742 ? 813  TYR   A CE2  1 ? 
ATOM   1812 C CZ   . TYR   A 1 119 ? 4.628   -66.125 135.53  1   108.777 ? 813  TYR   A CZ   1 ? 
ATOM   1813 O OH   . TYR   A 1 119 ? 3.363   -66.441 135.917 1   119.587 ? 813  TYR   A OH   1 ? 
ATOM   1814 H H    . TYR   A 1 119 ? 10.005  -67.004 135.154 1   94.004  ? 813  TYR   A H    1 c 
ATOM   1815 H HA   . TYR   A 1 119 ? 8.447   -66.746 132.964 1   94.66   ? 813  TYR   A HA   1 c 
ATOM   1816 H HB2  . TYR   A 1 119 ? 9.181   -64.956 135.02  1   100.765 ? 813  TYR   A HB2  1 c 
ATOM   1817 H HB3  . TYR   A 1 119 ? 8.568   -64.309 133.694 1   100.771 ? 813  TYR   A HB3  1 c 
ATOM   1818 H HD1  . TYR   A 1 119 ? 6.336   -65.271 132.91  1   114.09  ? 813  TYR   A HD1  1 c 
ATOM   1819 H HD2  . TYR   A 1 119 ? 7.633   -65.789 136.678 1   105.643 ? 813  TYR   A HD2  1 c 
ATOM   1820 H HE1  . TYR   A 1 119 ? 4.184   -65.812 133.578 1   116.195 ? 813  TYR   A HE1  1 c 
ATOM   1821 H HE2  . TYR   A 1 119 ? 5.481   -66.332 137.354 1   104.803 ? 813  TYR   A HE2  1 c 
ATOM   1822 H HH   . TYR   A 1 119 ? 2.83    -66.391 135.202 0   119.12  ? 813  TYR   A HH   1 c 
ATOM   1823 N N    . LEU   A 1 120 ? 11.296  -65.247 132.776 1   88.634  ? 814  LEU   A N    1 ? 
ATOM   1824 C CA   . LEU   A 1 120 ? 12.274  -64.631 131.895 1   84.005  ? 814  LEU   A CA   1 ? 
ATOM   1825 C C    . LEU   A 1 120 ? 12.688  -65.578 130.777 1   80.073  ? 814  LEU   A C    1 ? 
ATOM   1826 O O    . LEU   A 1 120 ? 12.75   -65.174 129.633 1   91.504  ? 814  LEU   A O    1 ? 
ATOM   1827 C CB   . LEU   A 1 120 ? 13.501  -64.217 132.702 1   92.243  ? 814  LEU   A CB   1 ? 
ATOM   1828 C CG   . LEU   A 1 120 ? 13.322  -62.989 133.596 1   105.081 ? 814  LEU   A CG   1 ? 
ATOM   1829 C CD1  . LEU   A 1 120 ? 14.503  -62.831 134.528 1   110.994 ? 814  LEU   A CD1  1 ? 
ATOM   1830 C CD2  . LEU   A 1 120 ? 13.131  -61.729 132.763 1   106.891 ? 814  LEU   A CD2  1 ? 
ATOM   1831 H H    . LEU   A 1 120 ? 11.498  -65.322 133.664 1   87.741  ? 814  LEU   A H    1 c 
ATOM   1832 H HA   . LEU   A 1 120 ? 11.863  -63.827 131.49  1   85.833  ? 814  LEU   A HA   1 c 
ATOM   1833 H HB2  . LEU   A 1 120 ? 13.769  -64.978 133.268 1   93.037  ? 814  LEU   A HB2  1 c 
ATOM   1834 H HB3  . LEU   A 1 120 ? 14.238  -64.038 132.073 1   92.931  ? 814  LEU   A HB3  1 c 
ATOM   1835 H HG   . LEU   A 1 120 ? 12.508  -63.123 134.147 1   104.02  ? 814  LEU   A HG   1 c 
ATOM   1836 H HD11 . LEU   A 1 120 ? 14.586  -63.622 135.085 1   109.205 ? 814  LEU   A HD11 1 c 
ATOM   1837 H HD12 . LEU   A 1 120 ? 14.37   -62.051 135.092 1   109.205 ? 814  LEU   A HD12 1 c 
ATOM   1838 H HD13 . LEU   A 1 120 ? 15.316  -62.716 134.006 1   109.205 ? 814  LEU   A HD13 1 c 
ATOM   1839 H HD21 . LEU   A 1 120 ? 12.274  -61.766 132.307 1   106.061 ? 814  LEU   A HD21 1 c 
ATOM   1840 H HD22 . LEU   A 1 120 ? 13.845  -61.663 132.106 1   106.284 ? 814  LEU   A HD22 1 c 
ATOM   1841 H HD23 . LEU   A 1 120 ? 13.154  -60.95  133.344 1   106.284 ? 814  LEU   A HD23 1 c 
ATOM   1842 N N    . LEU   A 1 121 ? 13.064  -66.808 131.123 1   88.884  ? 815  LEU   A N    1 ? 
ATOM   1843 C CA   . LEU   A 1 121 ? 13.517  -67.775 130.141 1   90.484  ? 815  LEU   A CA   1 ? 
ATOM   1844 C C    . LEU   A 1 121 ? 12.376  -68.126 129.198 1   85.58   ? 815  LEU   A C    1 ? 
ATOM   1845 O O    . LEU   A 1 121 ? 12.609  -68.328 128.018 1   103.979 ? 815  LEU   A O    1 ? 
ATOM   1846 C CB   . LEU   A 1 121 ? 14.069  -69.022 130.825 1   96.812  ? 815  LEU   A CB   1 ? 
ATOM   1847 C CG   . LEU   A 1 121 ? 15.382  -68.831 131.583 1   92.137  ? 815  LEU   A CG   1 ? 
ATOM   1848 C CD1  . LEU   A 1 121 ? 15.814  -70.156 132.203 1   99.458  ? 815  LEU   A CD1  1 ? 
ATOM   1849 C CD2  . LEU   A 1 121 ? 16.455  -68.268 130.666 1   89.458  ? 815  LEU   A CD2  1 ? 
ATOM   1850 H H    . LEU   A 1 121 ? 13.04   -67.053 132.004 1   87.149  ? 815  LEU   A H    1 c 
ATOM   1851 H HA   . LEU   A 1 121 ? 14.235  -67.354 129.606 1   90.291  ? 815  LEU   A HA   1 c 
ATOM   1852 H HB2  . LEU   A 1 121 ? 13.39   -69.352 131.458 1   94.203  ? 815  LEU   A HB2  1 c 
ATOM   1853 H HB3  . LEU   A 1 121 ? 14.203  -69.716 130.139 1   94.202  ? 815  LEU   A HB3  1 c 
ATOM   1854 H HG   . LEU   A 1 121 ? 15.227  -68.181 132.315 1   93.934  ? 815  LEU   A HG   1 c 
ATOM   1855 H HD11 . LEU   A 1 121 ? 15.117  -70.48  132.798 1   97.186  ? 815  LEU   A HD11 1 c 
ATOM   1856 H HD12 . LEU   A 1 121 ? 16.635  -70.027 132.707 1   97.22   ? 815  LEU   A HD12 1 c 
ATOM   1857 H HD13 . LEU   A 1 121 ? 15.967  -70.808 131.5   1   97.182  ? 815  LEU   A HD13 1 c 
ATOM   1858 H HD21 . LEU   A 1 121 ? 16.276  -67.329 130.491 1   90.246  ? 815  LEU   A HD21 1 c 
ATOM   1859 H HD22 . LEU   A 1 121 ? 16.454  -68.76  129.828 1   90.26   ? 815  LEU   A HD22 1 c 
ATOM   1860 H HD23 . LEU   A 1 121 ? 17.324  -68.357 131.091 1   90.246  ? 815  LEU   A HD23 1 c 
ATOM   1861 N N    . ASN   A 1 122 ? 11.156  -68.185 129.731 1   87.849  ? 816  ASN   A N    1 ? 
ATOM   1862 C CA   . ASN   A 1 122 ? 9.965   -68.459 128.944 1   92.371  ? 816  ASN   A CA   1 ? 
ATOM   1863 C C    . ASN   A 1 122 ? 9.68    -67.341 127.95  1   83.395  ? 816  ASN   A C    1 ? 
ATOM   1864 O O    . ASN   A 1 122 ? 9.305   -67.608 126.825 1   93.064  ? 816  ASN   A O    1 ? 
ATOM   1865 C CB   . ASN   A 1 122 ? 8.744   -68.638 129.83  1   105.2   ? 816  ASN   A CB   1 ? 
ATOM   1866 C CG   . ASN   A 1 122 ? 8.657   -70.05  130.342 1   107.999 ? 816  ASN   A CG   1 ? 
ATOM   1867 O OD1  . ASN   A 1 122 ? 9.581   -70.838 130.131 1   100.325 ? 816  ASN   A OD1  1 ? 
ATOM   1868 N ND2  . ASN   A 1 122 ? 7.566   -70.386 131.009 1   127.216 ? 816  ASN   A ND2  1 ? 
ATOM   1869 H H    . ASN   A 1 122 ? 11.061  -68.058 130.631 1   88.532  ? 816  ASN   A H    1 c 
ATOM   1870 H HA   . ASN   A 1 122 ? 10.106  -69.294 128.444 1   92.143  ? 816  ASN   A HA   1 c 
ATOM   1871 H HB2  . ASN   A 1 122 ? 8.794   -68.021 130.585 1   102.561 ? 816  ASN   A HB2  1 c 
ATOM   1872 H HB3  . ASN   A 1 122 ? 7.937   -68.431 129.318 1   102.839 ? 816  ASN   A HB3  1 c 
ATOM   1873 H HD21 . ASN   A 1 122 ? 7.477   -71.211 131.325 1   120.747 ? 816  ASN   A HD21 1 c 
ATOM   1874 H HD22 . ASN   A 1 122 ? 6.924   -69.788 131.142 1   120.787 ? 816  ASN   A HD22 1 c 
ATOM   1875 N N    . TRP   A 1 123 ? 9.824   -66.094 128.376 1   82.907  ? 817  TRP   A N    1 ? 
ATOM   1876 C CA   . TRP   A 1 123 ? 9.66    -64.969 127.47  1   87.295  ? 817  TRP   A CA   1 ? 
ATOM   1877 C C    . TRP   A 1 123 ? 10.665  -65.013 126.334 1   80.53   ? 817  TRP   A C    1 ? 
ATOM   1878 O O    . TRP   A 1 123 ? 10.344  -64.699 125.205 1   86.171  ? 817  TRP   A O    1 ? 
ATOM   1879 C CB   . TRP   A 1 123 ? 9.817   -63.649 128.225 1   90.226  ? 817  TRP   A CB   1 ? 
ATOM   1880 C CG   . TRP   A 1 123 ? 8.68    -63.434 129.165 1   86.999  ? 817  TRP   A CG   1 ? 
ATOM   1881 C CD1  . TRP   A 1 123 ? 7.434   -63.979 129.094 1   93.777  ? 817  TRP   A CD1  1 ? 
ATOM   1882 C CD2  . TRP   A 1 123 ? 8.706   -62.595 130.32  1   84.462  ? 817  TRP   A CD2  1 ? 
ATOM   1883 N NE1  . TRP   A 1 123 ? 6.676   -63.535 130.138 1   97.805  ? 817  TRP   A NE1  1 ? 
ATOM   1884 C CE2  . TRP   A 1 123 ? 7.429   -62.687 130.903 1   90.655  ? 817  TRP   A CE2  1 ? 
ATOM   1885 C CE3  . TRP   A 1 123 ? 9.677   -61.785 130.901 1   89.171  ? 817  TRP   A CE3  1 ? 
ATOM   1886 C CZ2  . TRP   A 1 123 ? 7.097   -61.988 132.055 1   96.033  ? 817  TRP   A CZ2  1 ? 
ATOM   1887 C CZ3  . TRP   A 1 123 ? 9.344   -61.099 132.043 1   96.09   ? 817  TRP   A CZ3  1 ? 
ATOM   1888 C CH2  . TRP   A 1 123 ? 8.07    -61.188 132.6   1   95.254  ? 817  TRP   A CH2  1 ? 
ATOM   1889 H H    . TRP   A 1 123 ? 10.026  -65.933 129.253 1   84.125  ? 817  TRP   A H    1 c 
ATOM   1890 H HA   . TRP   A 1 123 ? 8.747   -65.007 127.082 1   85.794  ? 817  TRP   A HA   1 c 
ATOM   1891 H HB2  . TRP   A 1 123 ? 10.656  -63.67  128.731 1   88.792  ? 817  TRP   A HB2  1 c 
ATOM   1892 H HB3  . TRP   A 1 123 ? 9.844   -62.913 127.577 1   88.753  ? 817  TRP   A HB3  1 c 
ATOM   1893 H HD1  . TRP   A 1 123 ? 7.126   -64.578 128.433 1   92.933  ? 817  TRP   A HD1  1 c 
ATOM   1894 H HE1  . TRP   A 1 123 ? 5.845   -63.757 130.291 1   95.009  ? 817  TRP   A HE1  1 c 
ATOM   1895 H HE3  . TRP   A 1 123 ? 10.537  -61.714 130.523 1   89.717  ? 817  TRP   A HE3  1 c 
ATOM   1896 H HZ2  . TRP   A 1 123 ? 6.239   -62.05  132.436 1   94.511  ? 817  TRP   A HZ2  1 c 
ATOM   1897 H HZ3  . TRP   A 1 123 ? 9.987   -60.542 132.45  1   94.145  ? 817  TRP   A HZ3  1 c 
ATOM   1898 H HH2  . TRP   A 1 123 ? 7.879   -60.708 133.387 1   95.499  ? 817  TRP   A HH2  1 c 
ATOM   1899 N N    . CYS   A 1 124 ? 11.9    -65.348 126.664 1   88.493  ? 818  CYS   A N    1 ? 
ATOM   1900 C CA   . CYS   A 1 124 ? 12.948  -65.497 125.679 1   90.238  ? 818  CYS   A CA   1 ? 
ATOM   1901 C C    . CYS   A 1 124 ? 12.552  -66.533 124.637 1   82.936  ? 818  CYS   A C    1 ? 
ATOM   1902 O O    . CYS   A 1 124 ? 12.838  -66.341 123.473 1   85.798  ? 818  CYS   A O    1 ? 
ATOM   1903 C CB   . CYS   A 1 124 ? 14.245  -65.928 126.347 1   95.54   ? 818  CYS   A CB   1 ? 
ATOM   1904 S SG   . CYS   A 1 124 ? 15.03   -64.594 127.277 1   90.172  ? 818  CYS   A SG   1 ? 
ATOM   1905 H H    . CYS   A 1 124 ? 12.104  -65.484 127.545 1   86.988  ? 818  CYS   A H    1 c 
ATOM   1906 H HA   . CYS   A 1 124 ? 13.077  -64.624 125.228 1   89.414  ? 818  CYS   A HA   1 c 
ATOM   1907 H HB2  . CYS   A 1 124 ? 14.064  -66.673 126.96  1   93.227  ? 818  CYS   A HB2  1 c 
ATOM   1908 H HB3  . CYS   A 1 124 ? 14.874  -66.243 125.66  1   93.159  ? 818  CYS   A HB3  1 c 
ATOM   1909 H HG   . CYS   A 1 124 ? 15.99   -65.214 127.686 0   90.7    ? 818  CYS   A HG   1 c 
ATOM   1910 N N    . VAL   A 1 125 ? 11.945  -67.64  125.074 1   88.427  ? 819  VAL   A N    1 ? 
ATOM   1911 C CA   . VAL   A 1 125 ? 11.552  -68.724 124.189 1   87.752  ? 819  VAL   A CA   1 ? 
ATOM   1912 C C    . VAL   A 1 125 ? 10.456  -68.254 123.251 1   85.78   ? 819  VAL   A C    1 ? 
ATOM   1913 O O    . VAL   A 1 125 ? 10.478  -68.571 122.071 1   92.018  ? 819  VAL   A O    1 ? 
ATOM   1914 C CB   . VAL   A 1 125 ? 11.054  -69.953 124.96  1   90.818  ? 819  VAL   A CB   1 ? 
ATOM   1915 C CG1  . VAL   A 1 125 ? 10.523  -71.023 124.016 1   94.293  ? 819  VAL   A CG1  1 ? 
ATOM   1916 C CG2  . VAL   A 1 125 ? 12.145  -70.518 125.855 1   99.164  ? 819  VAL   A CG2  1 ? 
ATOM   1917 H H    . VAL   A 1 125 ? 11.766  -67.721 125.967 1   87.074  ? 819  VAL   A H    1 c 
ATOM   1918 H HA   . VAL   A 1 125 ? 12.329  -68.984 123.657 1   88.053  ? 819  VAL   A HA   1 c 
ATOM   1919 H HB   . VAL   A 1 125 ? 10.31   -69.657 125.535 1   92.376  ? 819  VAL   A HB   1 c 
ATOM   1920 H HG11 . VAL   A 1 125 ? 11.147  -71.144 123.28  1   93.269  ? 819  VAL   A HG11 1 c 
ATOM   1921 H HG12 . VAL   A 1 125 ? 9.658   -70.751 123.666 1   93.224  ? 819  VAL   A HG12 1 c 
ATOM   1922 H HG13 . VAL   A 1 125 ? 10.427  -71.862 124.498 1   93.281  ? 819  VAL   A HG13 1 c 
ATOM   1923 H HG21 . VAL   A 1 125 ? 11.778  -71.232 126.404 1   96.579  ? 819  VAL   A HG21 1 c 
ATOM   1924 H HG22 . VAL   A 1 125 ? 12.494  -69.82  126.428 1   96.49   ? 819  VAL   A HG22 1 c 
ATOM   1925 H HG23 . VAL   A 1 125 ? 12.865  -70.872 125.305 1   96.539  ? 819  VAL   A HG23 1 c 
ATOM   1926 N N    . GLN   A 1 126 ? 9.496   -67.513 123.8   1   83.681  ? 820  GLN   A N    1 ? 
ATOM   1927 C CA   . GLN   A 1 126 ? 8.32    -67.091 123.062 1   83.047  ? 820  GLN   A CA   1 ? 
ATOM   1928 C C    . GLN   A 1 126 ? 8.675   -66.07  121.994 1   86.074  ? 820  GLN   A C    1 ? 
ATOM   1929 O O    . GLN   A 1 126 ? 8.089   -66.089 120.921 1   96.304  ? 820  GLN   A O    1 ? 
ATOM   1930 C CB   . GLN   A 1 126 ? 7.302   -66.501 124.028 1   87.334  ? 820  GLN   A CB   1 ? 
ATOM   1931 C CG   . GLN   A 1 126 ? 6.609   -67.572 124.856 1   87.195  ? 820  GLN   A CG   1 ? 
ATOM   1932 C CD   . GLN   A 1 126 ? 5.647   -66.994 125.858 1   80.26   ? 820  GLN   A CD   1 ? 
ATOM   1933 O OE1  . GLN   A 1 126 ? 5.116   -65.903 125.679 1   94.978  ? 820  GLN   A OE1  1 ? 
ATOM   1934 N NE2  . GLN   A 1 126 ? 5.415   -67.722 126.928 1   93.423  ? 820  GLN   A NE2  1 ? 
ATOM   1935 H H    . GLN   A 1 126 ? 9.575   -67.263 124.675 1   84.127  ? 820  GLN   A H    1 c 
ATOM   1936 H HA   . GLN   A 1 126 ? 7.925   -67.887 122.623 1   84.531  ? 820  GLN   A HA   1 c 
ATOM   1937 H HB2  . GLN   A 1 126 ? 7.754   -65.872 124.628 1   86.301  ? 820  GLN   A HB2  1 c 
ATOM   1938 H HB3  . GLN   A 1 126 ? 6.63    -66.001 123.52  1   86.353  ? 820  GLN   A HB3  1 c 
ATOM   1939 H HG2  . GLN   A 1 126 ? 6.124   -68.179 124.261 1   85.719  ? 820  GLN   A HG2  1 c 
ATOM   1940 H HG3  . GLN   A 1 126 ? 7.285   -68.099 125.332 1   85.703  ? 820  GLN   A HG3  1 c 
ATOM   1941 H HE21 . GLN   A 1 126 ? 4.963   -67.375 127.609 1   89.179  ? 820  GLN   A HE21 1 c 
ATOM   1942 H HE22 . GLN   A 1 126 ? 5.708   -68.559 126.972 1   89.112  ? 820  GLN   A HE22 1 c 
ATOM   1943 N N    . ILE   A 1 127 ? 9.6     -65.161 122.305 1   86.598  ? 821  ILE   A N    1 ? 
ATOM   1944 C CA   . ILE   A 1 127 ? 10.037  -64.172 121.333 1   89.928  ? 821  ILE   A CA   1 ? 
ATOM   1945 C C    . ILE   A 1 127 ? 10.765  -64.861 120.184 1   86.317  ? 821  ILE   A C    1 ? 
ATOM   1946 O O    . ILE   A 1 127 ? 10.578  -64.51  119.03  1   97.178  ? 821  ILE   A O    1 ? 
ATOM   1947 C CB   . ILE   A 1 127 ? 10.925  -63.11  121.994 1   87.435  ? 821  ILE   A CB   1 ? 
ATOM   1948 C CG1  . ILE   A 1 127 ? 10.126  -62.234 122.948 1   96.575  ? 821  ILE   A CG1  1 ? 
ATOM   1949 C CG2  . ILE   A 1 127 ? 11.636  -62.274 120.934 1   88.376  ? 821  ILE   A CG2  1 ? 
ATOM   1950 C CD1  . ILE   A 1 127 ? 10.88   -61.852 124.208 1   96.274  ? 821  ILE   A CD1  1 ? 
ATOM   1951 H H    . ILE   A 1 127 ? 9.964   -65.15  123.144 1   87.178  ? 821  ILE   A H    1 c 
ATOM   1952 H HA   . ILE   A 1 127 ? 9.245   -63.726 120.974 1   88.171  ? 821  ILE   A HA   1 c 
ATOM   1953 H HB   . ILE   A 1 127 ? 11.608  -63.576 122.516 1   89.781  ? 821  ILE   A HB   1 c 
ATOM   1954 H HG12 . ILE   A 1 127 ? 9.863   -61.415 122.479 1   94.29   ? 821  ILE   A HG12 1 c 
ATOM   1955 H HG13 . ILE   A 1 127 ? 9.308   -62.707 123.203 1   94.265  ? 821  ILE   A HG13 1 c 
ATOM   1956 H HG21 . ILE   A 1 127 ? 12.045  -61.499 121.353 1   88.116  ? 821  ILE   A HG21 1 c 
ATOM   1957 H HG22 . ILE   A 1 127 ? 10.993  -61.977 120.268 1   88.11   ? 821  ILE   A HG22 1 c 
ATOM   1958 H HG23 . ILE   A 1 127 ? 12.324  -62.806 120.502 1   88.182  ? 821  ILE   A HG23 1 c 
ATOM   1959 H HD11 . ILE   A 1 127 ? 11.284  -62.643 124.61  1   96.237  ? 821  ILE   A HD11 1 c 
ATOM   1960 H HD12 . ILE   A 1 127 ? 10.263  -61.444 124.846 1   96.333  ? 821  ILE   A HD12 1 c 
ATOM   1961 H HD13 . ILE   A 1 127 ? 11.582  -61.212 123.982 1   96.333  ? 821  ILE   A HD13 1 c 
ATOM   1962 N N    . ALA   A 1 128 ? 11.596  -65.845 120.508 1   87.311  ? 822  ALA   A N    1 ? 
ATOM   1963 C CA   . ALA   A 1 128 ? 12.34   -66.581 119.507 1   89.47   ? 822  ALA   A CA   1 ? 
ATOM   1964 C C    . ALA   A 1 128 ? 11.376  -67.31  118.582 1   87.036  ? 822  ALA   A C    1 ? 
ATOM   1965 O O    . ALA   A 1 128 ? 11.607  -67.379 117.376 1   102.108 ? 822  ALA   A O    1 ? 
ATOM   1966 C CB   . ALA   A 1 128 ? 13.284  -67.545 120.184 1   93.911  ? 822  ALA   A CB   1 ? 
ATOM   1967 H H    . ALA   A 1 128 ? 11.711  -66.063 121.388 1   87.608  ? 822  ALA   A H    1 c 
ATOM   1968 H HA   . ALA   A 1 128 ? 12.866  -65.931 118.964 1   89.422  ? 822  ALA   A HA   1 c 
ATOM   1969 H HB1  . ALA   A 1 128 ? 13.914  -67.052 120.736 1   92.562  ? 822  ALA   A HB1  1 c 
ATOM   1970 H HB2  . ALA   A 1 128 ? 12.779  -68.158 120.744 1   92.543  ? 822  ALA   A HB2  1 c 
ATOM   1971 H HB3  . ALA   A 1 128 ? 13.772  -68.051 119.513 1   92.562  ? 822  ALA   A HB3  1 c 
ATOM   1972 N N    . LYS   A 1 129 ? 10.304  -67.855 119.162 1   87.923  ? 823  LYS   A N    1 ? 
ATOM   1973 C CA   . LYS   A 1 129 ? 9.299   -68.589 118.407 1   98.729  ? 823  LYS   A CA   1 ? 
ATOM   1974 C C    . LYS   A 1 129 ? 8.571   -67.695 117.403 1   94.706  ? 823  LYS   A C    1 ? 
ATOM   1975 O O    . LYS   A 1 129 ? 8.306   -68.116 116.282 1   99.82   ? 823  LYS   A O    1 ? 
ATOM   1976 C CB   . LYS   A 1 129 ? 8.284   -69.213 119.367 1   94.345  ? 823  LYS   A CB   1 ? 
ATOM   1977 C CG   . LYS   A 1 129 ? 8.754   -70.495 119.993 1   86.421  ? 823  LYS   A CG   1 ? 
ATOM   1978 C CD   . LYS   A 1 129 ? 7.694   -71.126 120.879 1   88.834  ? 823  LYS   A CD   1 ? 
ATOM   1979 C CE   . LYS   A 1 129 ? 7.927   -72.572 121.109 1   89.868  ? 823  LYS   A CE   1 ? 
ATOM   1980 N NZ   . LYS   A 1 129 ? 6.81    -73.114 121.88  1   100.181 ? 823  LYS   A NZ   1 ? 
ATOM   1981 H H    . LYS   A 1 129 ? 10.2    -67.775 120.067 1   90.064  ? 823  LYS   A H    1 c 
ATOM   1982 H HA   . LYS   A 1 129 ? 9.752   -69.314 117.91  1   94.838  ? 823  LYS   A HA   1 c 
ATOM   1983 H HB2  . LYS   A 1 129 ? 8.08    -68.572 120.08  1   93.377  ? 823  LYS   A HB2  1 c 
ATOM   1984 H HB3  . LYS   A 1 129 ? 7.452   -69.391 118.878 1   93.364  ? 823  LYS   A HB3  1 c 
ATOM   1985 H HG2  . LYS   A 1 129 ? 8.993   -71.124 119.28  1   88.812  ? 823  LYS   A HG2  1 c 
ATOM   1986 H HG3  . LYS   A 1 129 ? 9.558   -70.314 120.525 1   88.772  ? 823  LYS   A HG3  1 c 
ATOM   1987 H HD2  . LYS   A 1 129 ? 7.684   -70.663 121.745 1   88.543  ? 823  LYS   A HD2  1 c 
ATOM   1988 H HD3  . LYS   A 1 129 ? 6.814   -71.006 120.461 1   88.635  ? 823  LYS   A HD3  1 c 
ATOM   1989 H HE2  . LYS   A 1 129 ? 7.99    -73.041 120.257 1   91.932  ? 823  LYS   A HE2  1 c 
ATOM   1990 H HE3  . LYS   A 1 129 ? 8.757   -72.705 121.602 1   91.947  ? 823  LYS   A HE3  1 c 
ATOM   1991 H HZ1  . LYS   A 1 129 ? 6.031   -72.981 121.435 1   96.762  ? 823  LYS   A HZ1  1 c 
ATOM   1992 H HZ2  . LYS   A 1 129 ? 6.766   -72.703 122.687 1   96.808  ? 823  LYS   A HZ2  1 c 
ATOM   1993 H HZ3  . LYS   A 1 129 ? 6.93    -74.003 122.007 1   96.845  ? 823  LYS   A HZ3  1 c 
ATOM   1994 N N    . GLY   A 1 130 ? 8.176   -66.498 117.841 1   86.879  ? 824  GLY   A N    1 ? 
ATOM   1995 C CA   . GLY   A 1 130 ? 7.512   -65.547 116.972 1   91.952  ? 824  GLY   A CA   1 ? 
ATOM   1996 C C    . GLY   A 1 130 ? 8.454   -65.051 115.886 1   85.973  ? 824  GLY   A C    1 ? 
ATOM   1997 O O    . GLY   A 1 130 ? 8.065   -64.924 114.74  1   106.057 ? 824  GLY   A O    1 ? 
ATOM   1998 H H    . GLY   A 1 130 ? 8.321   -66.269 118.714 1   89.87   ? 824  GLY   A H    1 c 
ATOM   1999 H HA2  . GLY   A 1 130 ? 6.728   -65.979 116.557 1   89.473  ? 824  GLY   A HA2  1 c 
ATOM   2000 H HA3  . GLY   A 1 130 ? 7.192   -64.787 117.507 1   89.681  ? 824  GLY   A HA3  1 c 
ATOM   2001 N N    . MET   A 1 131 ? 9.696   -64.782 116.268 1   94.215  ? 825  MET   A N    1 ? 
ATOM   2002 C CA   . MET   A 1 131 ? 10.693  -64.284 115.339 1   89.139  ? 825  MET   A CA   1 ? 
ATOM   2003 C C    . MET   A 1 131 ? 11.055  -65.373 114.34  1   82.418  ? 825  MET   A C    1 ? 
ATOM   2004 O O    . MET   A 1 131 ? 11.34   -65.047 113.203 1   90.591  ? 825  MET   A O    1 ? 
ATOM   2005 C CB   . MET   A 1 131 ? 11.957  -63.83  116.074 1   88.275  ? 825  MET   A CB   1 ? 
ATOM   2006 C CG   . MET   A 1 131 ? 11.759  -62.547 116.839 1   90.059  ? 825  MET   A CG   1 ? 
ATOM   2007 S SD   . MET   A 1 131 ? 11.344  -61.168 115.762 1   96.254  ? 825  MET   A SD   1 ? 
ATOM   2008 C CE   . MET   A 1 131 ? 12.937  -60.927 114.98  1   113.329 ? 825  MET   A CE   1 ? 
ATOM   2009 H H    . MET   A 1 131 ? 9.934   -64.906 117.142 1   90.975  ? 825  MET   A H    1 c 
ATOM   2010 H HA   . MET   A 1 131 ? 10.303  -63.521 114.843 1   88.771  ? 825  MET   A HA   1 c 
ATOM   2011 H HB2  . MET   A 1 131 ? 12.232  -64.537 116.696 1   88.933  ? 825  MET   A HB2  1 c 
ATOM   2012 H HB3  . MET   A 1 131 ? 12.676  -63.707 115.42  1   89.096  ? 825  MET   A HB3  1 c 
ATOM   2013 H HG2  . MET   A 1 131 ? 11.04   -62.663 117.49  1   90.808  ? 825  MET   A HG2  1 c 
ATOM   2014 H HG3  . MET   A 1 131 ? 12.578  -62.331 117.329 1   90.774  ? 825  MET   A HG3  1 c 
ATOM   2015 H HE1  . MET   A 1 131 ? 12.947  -60.064 114.528 1   108.703 ? 825  MET   A HE1  1 c 
ATOM   2016 H HE2  . MET   A 1 131 ? 13.637  -60.946 115.659 1   108.59  ? 825  MET   A HE2  1 c 
ATOM   2017 H HE3  . MET   A 1 131 ? 13.092  -61.639 114.332 1   108.579 ? 825  MET   A HE3  1 c 
ATOM   2018 N N    . ASN   A 1 132 ? 11.09   -66.638 114.777 1   80.261  ? 826  ASN   A N    1 ? 
ATOM   2019 C CA   . ASN   A 1 132 ? 11.325  -67.749 113.873 1   88.558  ? 826  ASN   A CA   1 ? 
ATOM   2020 C C    . ASN   A 1 132 ? 10.164  -67.853 112.89  1   89.515  ? 826  ASN   A C    1 ? 
ATOM   2021 O O    . ASN   A 1 132 ? 10.362  -68.152 111.715 1   87.25   ? 826  ASN   A O    1 ? 
ATOM   2022 C CB   . ASN   A 1 132 ? 11.521  -69.056 114.63  1   92.217  ? 826  ASN   A CB   1 ? 
ATOM   2023 C CG   . ASN   A 1 132 ? 11.835  -70.213 113.714 1   87.185  ? 826  ASN   A CG   1 ? 
ATOM   2024 O OD1  . ASN   A 1 132 ? 12.865  -70.194 113.038 1   94.957  ? 826  ASN   A OD1  1 ? 
ATOM   2025 N ND2  . ASN   A 1 132 ? 10.999  -71.239 113.703 1   88.972  ? 826  ASN   A ND2  1 ? 
ATOM   2026 H H    . ASN   A 1 132 ? 10.971  -66.812 115.667 1   82.76   ? 826  ASN   A H    1 c 
ATOM   2027 H HA   . ASN   A 1 132 ? 12.151  -67.569 113.369 1   87.687  ? 826  ASN   A HA   1 c 
ATOM   2028 H HB2  . ASN   A 1 132 ? 12.256  -68.948 115.266 1   90.247  ? 826  ASN   A HB2  1 c 
ATOM   2029 H HB3  . ASN   A 1 132 ? 10.713  -69.256 115.14  1   90.446  ? 826  ASN   A HB3  1 c 
ATOM   2030 H HD21 . ASN   A 1 132 ? 11.167  -71.938 113.183 1   88.476  ? 826  ASN   A HD21 1 c 
ATOM   2031 H HD22 . ASN   A 1 132 ? 10.272  -71.231 114.211 1   88.473  ? 826  ASN   A HD22 1 c 
ATOM   2032 N N    . TYR   A 1 133 ? 8.949   -67.604 113.386 1   93.824  ? 827  TYR   A N    1 ? 
ATOM   2033 C CA   . TYR   A 1 133 ? 7.764   -67.631 112.546 1   93.785  ? 827  TYR   A CA   1 ? 
ATOM   2034 C C    . TYR   A 1 133 ? 7.903   -66.548 111.486 1   88.848  ? 827  TYR   A C    1 ? 
ATOM   2035 O O    . TYR   A 1 133 ? 7.565   -66.764 110.339 1   100.909 ? 827  TYR   A O    1 ? 
ATOM   2036 C CB   . TYR   A 1 133 ? 6.473   -67.437 113.346 1   91.151  ? 827  TYR   A CB   1 ? 
ATOM   2037 C CG   . TYR   A 1 133 ? 5.258   -67.244 112.46  1   90.018  ? 827  TYR   A CG   1 ? 
ATOM   2038 C CD1  . TYR   A 1 133 ? 4.576   -68.33  111.947 1   100.57  ? 827  TYR   A CD1  1 ? 
ATOM   2039 C CD2  . TYR   A 1 133 ? 4.822   -65.978 112.104 1   89.711  ? 827  TYR   A CD2  1 ? 
ATOM   2040 C CE1  . TYR   A 1 133 ? 3.483   -68.166 111.115 1   102.875 ? 827  TYR   A CE1  1 ? 
ATOM   2041 C CE2  . TYR   A 1 133 ? 3.721   -65.8   111.282 1   81.331  ? 827  TYR   A CE2  1 ? 
ATOM   2042 C CZ   . TYR   A 1 133 ? 3.049   -66.899 110.788 1   86.259  ? 827  TYR   A CZ   1 ? 
ATOM   2043 O OH   . TYR   A 1 133 ? 1.973   -66.777 109.965 1   92.153  ? 827  TYR   A OH   1 ? 
ATOM   2044 H H    . TYR   A 1 133 ? 8.853   -67.423 114.277 1   92.596  ? 827  TYR   A H    1 c 
ATOM   2045 H HA   . TYR   A 1 133 ? 7.726   -68.51  112.092 1   92.614  ? 827  TYR   A HA   1 c 
ATOM   2046 H HB2  . TYR   A 1 133 ? 6.332   -68.226 113.915 1   91.686  ? 827  TYR   A HB2  1 c 
ATOM   2047 H HB3  . TYR   A 1 133 ? 6.574   -66.652 113.927 1   91.6    ? 827  TYR   A HB3  1 c 
ATOM   2048 H HD1  . TYR   A 1 133 ? 4.857   -69.201 112.169 1   98.568  ? 827  TYR   A HD1  1 c 
ATOM   2049 H HD2  . TYR   A 1 133 ? 5.275   -65.221 112.439 1   87.888  ? 827  TYR   A HD2  1 c 
ATOM   2050 H HE1  . TYR   A 1 133 ? 3.024   -68.92  110.785 1   97.955  ? 827  TYR   A HE1  1 c 
ATOM   2051 H HE2  . TYR   A 1 133 ? 3.436   -64.931 111.054 1   84.625  ? 827  TYR   A HE2  1 c 
ATOM   2052 H HH   . TYR   A 1 133 ? 1.69    -67.554 109.739 0   91.69   ? 827  TYR   A HH   1 c 
ATOM   2053 N N    . LEU   A 1 134 ? 8.368   -65.372 111.887 1   87.611  ? 828  LEU   A N    1 ? 
ATOM   2054 C CA   . LEU   A 1 134 ? 8.601   -64.292 110.947 1   86.136  ? 828  LEU   A CA   1 ? 
ATOM   2055 C C    . LEU   A 1 134 ? 9.626   -64.735 109.908 1   90.112  ? 828  LEU   A C    1 ? 
ATOM   2056 O O    . LEU   A 1 134 ? 9.52    -64.4   108.747 1   96.882  ? 828  LEU   A O    1 ? 
ATOM   2057 C CB   . LEU   A 1 134 ? 9.08    -63.049 111.693 1   96.896  ? 828  LEU   A CB   1 ? 
ATOM   2058 C CG   . LEU   A 1 134 ? 8.047   -62.32  112.563 1   91.194  ? 828  LEU   A CG   1 ? 
ATOM   2059 C CD1  . LEU   A 1 134 ? 8.588   -60.96  112.967 1   97.605  ? 828  LEU   A CD1  1 ? 
ATOM   2060 C CD2  . LEU   A 1 134 ? 6.707   -62.198 111.881 1   93.092  ? 828  LEU   A CD2  1 ? 
ATOM   2061 H H    . LEU   A 1 134 ? 8.538   -65.23  112.774 1   87.75   ? 828  LEU   A H    1 c 
ATOM   2062 H HA   . LEU   A 1 134 ? 7.75    -64.092 110.483 1   89.136  ? 828  LEU   A HA   1 c 
ATOM   2063 H HB2  . LEU   A 1 134 ? 9.836   -63.309 112.267 1   92.984  ? 828  LEU   A HB2  1 c 
ATOM   2064 H HB3  . LEU   A 1 134 ? 9.429   -62.41  111.029 1   93.045  ? 828  LEU   A HB3  1 c 
ATOM   2065 H HG   . LEU   A 1 134 ? 7.916   -62.848 113.39  1   93.822  ? 828  LEU   A HG   1 c 
ATOM   2066 H HD11 . LEU   A 1 134 ? 9.428   -61.073 113.442 1   95.747  ? 828  LEU   A HD11 1 c 
ATOM   2067 H HD12 . LEU   A 1 134 ? 7.948   -60.514 113.546 1   96.025  ? 828  LEU   A HD12 1 c 
ATOM   2068 H HD13 . LEU   A 1 134 ? 8.736   -60.42  112.173 1   95.732  ? 828  LEU   A HD13 1 c 
ATOM   2069 H HD21 . LEU   A 1 134 ? 6.243   -63.051 111.919 1   92.473  ? 828  LEU   A HD21 1 c 
ATOM   2070 H HD22 . LEU   A 1 134 ? 6.837   -61.941 110.953 1   92.498  ? 828  LEU   A HD22 1 c 
ATOM   2071 H HD23 . LEU   A 1 134 ? 6.173   -61.521 112.331 1   92.556  ? 828  LEU   A HD23 1 c 
ATOM   2072 N N    . GLU   A 1 135 ? 10.641  -65.484 110.331 1   108.447 ? 829  GLU   A N    1 ? 
ATOM   2073 C CA   . GLU   A 1 135 ? 11.661  -65.988 109.426 1   107.795 ? 829  GLU   A CA   1 ? 
ATOM   2074 C C    . GLU   A 1 135 ? 11.016  -66.923 108.409 1   97.627  ? 829  GLU   A C    1 ? 
ATOM   2075 O O    . GLU   A 1 135 ? 11.352  -66.873 107.235 1   112.641 ? 829  GLU   A O    1 ? 
ATOM   2076 C CB   . GLU   A 1 135 ? 12.761  -66.681 110.229 1   117.363 ? 829  GLU   A CB   1 ? 
ATOM   2077 C CG   . GLU   A 1 135 ? 13.815  -67.382 109.378 1   121.974 ? 829  GLU   A CG   1 ? 
ATOM   2078 C CD   . GLU   A 1 135 ? 15.217  -67.346 109.952 1   126.586 ? 829  GLU   A CD   1 ? 
ATOM   2079 O OE1  . GLU   A 1 135 ? 15.414  -67.228 111.185 1   134.833 ? 829  GLU   A OE1  1 ? 
ATOM   2080 O OE2  . GLU   A 1 135 ? 16.132  -67.418 109.113 1   134.633 ? 829  GLU   A OE2  1 ? 
ATOM   2081 H H    . GLU   A 1 135 ? 10.713  -65.677 111.221 1   103.449 ? 829  GLU   A H    1 c 
ATOM   2082 H HA   . GLU   A 1 135 ? 12.055  -65.219 108.943 1   107.604 ? 829  GLU   A HA   1 c 
ATOM   2083 H HB2  . GLU   A 1 135 ? 13.201  -66.012 110.795 1   116.213 ? 829  GLU   A HB2  1 c 
ATOM   2084 H HB3  . GLU   A 1 135 ? 12.352  -67.344 110.819 1   115.847 ? 829  GLU   A HB3  1 c 
ATOM   2085 H HG2  . GLU   A 1 135 ? 13.554  -68.32  109.258 1   121.916 ? 829  GLU   A HG2  1 c 
ATOM   2086 H HG3  . GLU   A 1 135 ? 13.834  -66.967 108.489 1   121.781 ? 829  GLU   A HG3  1 c 
ATOM   2087 N N    . ASP   A 1 136 ? 10.105  -67.788 108.857 1   102.573 ? 830  ASP   A N    1 ? 
ATOM   2088 C CA   . ASP   A 1 136 ? 9.393   -68.686 107.953 1   111.256 ? 830  ASP   A CA   1 ? 
ATOM   2089 C C    . ASP   A 1 136 ? 8.632   -67.873 106.91  1   106.906 ? 830  ASP   A C    1 ? 
ATOM   2090 O O    . ASP   A 1 136 ? 8.622   -68.211 105.736 1   108.466 ? 830  ASP   A O    1 ? 
ATOM   2091 C CB   . ASP   A 1 136 ? 8.44    -69.613 108.69  1   107.488 ? 830  ASP   A CB   1 ? 
ATOM   2092 C CG   . ASP   A 1 136 ? 9.124   -70.718 109.473 1   104.302 ? 830  ASP   A CG   1 ? 
ATOM   2093 O OD1  . ASP   A 1 136 ? 10.314  -70.939 109.222 1   122.333 ? 830  ASP   A OD1  1 ? 
ATOM   2094 O OD2  . ASP   A 1 136 ? 8.479   -71.312 110.35  1   112.365 ? 830  ASP   A OD2  1 ? 
ATOM   2095 H H    . ASP   A 1 136 ? 9.923   -67.829 109.752 1   103.326 ? 830  ASP   A H    1 c 
ATOM   2096 H HA   . ASP   A 1 136 ? 10.058  -69.24  107.485 1   108.104 ? 830  ASP   A HA   1 c 
ATOM   2097 H HB2  . ASP   A 1 136 ? 7.898   -69.086 109.313 1   107.544 ? 830  ASP   A HB2  1 c 
ATOM   2098 H HB3  . ASP   A 1 136 ? 7.834   -70.029 108.042 1   107.572 ? 830  ASP   A HB3  1 c 
ATOM   2099 N N    . ARG   A 1 137 ? 7.988   -66.802 107.368 1   116.414 ? 831  ARG   A N    1 ? 
ATOM   2100 C CA   . ARG   A 1 137 ? 7.315   -65.859 106.495 1   109.856 ? 831  ARG   A CA   1 ? 
ATOM   2101 C C    . ARG   A 1 137 ? 8.322   -65.166 105.595 1   117.714 ? 831  ARG   A C    1 ? 
ATOM   2102 O O    . ARG   A 1 137 ? 7.98    -64.849 104.465 1   150.137 ? 831  ARG   A O    1 ? 
ATOM   2103 C CB   . ARG   A 1 137 ? 6.525   -64.818 107.295 1   108.59  ? 831  ARG   A CB   1 ? 
ATOM   2104 C CG   . ARG   A 1 137 ? 5.191   -65.348 107.81  1   113.592 ? 831  ARG   A CG   1 ? 
ATOM   2105 C CD   . ARG   A 1 137 ? 4.729   -66.653 107.148 1   108.058 ? 831  ARG   A CD   1 ? 
ATOM   2106 N NE   . ARG   A 1 137 ? 3.333   -66.556 106.714 1   113.99  ? 831  ARG   A NE   1 ? 
ATOM   2107 C CZ   . ARG   A 1 137 ? 2.838   -65.657 105.853 1   117.707 ? 831  ARG   A CZ   1 ? 
ATOM   2108 N NH1  . ARG   A 1 137 ? 1.569   -65.694 105.513 1   129.771 ? 831  ARG   A NH1  1 ? 
ATOM   2109 N NH2  . ARG   A 1 137 ? 3.597   -64.726 105.306 1   117.293 ? 831  ARG   A NH2  1 ? 
ATOM   2110 H H    . ARG   A 1 137 ? 7.959   -66.656 108.27  1   112.457 ? 831  ARG   A H    1 c 
ATOM   2111 H HA   . ARG   A 1 137 ? 6.702   -66.364 105.913 1   112.415 ? 831  ARG   A HA   1 c 
ATOM   2112 H HB2  . ARG   A 1 137 ? 7.065   -64.522 108.058 1   109.972 ? 831  ARG   A HB2  1 c 
ATOM   2113 H HB3  . ARG   A 1 137 ? 6.357   -64.037 106.725 1   110.174 ? 831  ARG   A HB3  1 c 
ATOM   2114 H HG2  . ARG   A 1 137 ? 5.265   -65.498 108.777 1   111.182 ? 831  ARG   A HG2  1 c 
ATOM   2115 H HG3  . ARG   A 1 137 ? 4.504   -64.66  107.678 1   111.253 ? 831  ARG   A HG3  1 c 
ATOM   2116 H HD2  . ARG   A 1 137 ? 5.281   -66.869 106.376 1   110.658 ? 831  ARG   A HD2  1 c 
ATOM   2117 H HD3  . ARG   A 1 137 ? 4.815   -67.385 107.792 1   110.662 ? 831  ARG   A HD3  1 c 
ATOM   2118 H HE   . ARG   A 1 137 ? 2.773   -67.136 107.045 1   113.647 ? 831  ARG   A HE   1 c 
ATOM   2119 H HH11 . ARG   A 1 137 ? 1.035   -66.307 105.86  1   125.705 ? 831  ARG   A HH11 1 c 
ATOM   2120 H HH12 . ARG   A 1 137 ? 1.251   -65.103 104.936 1   125.81  ? 831  ARG   A HH12 1 c 
ATOM   2121 H HH21 . ARG   A 1 137 ? 4.353   -64.953 104.906 1   117.364 ? 831  ARG   A HH21 1 c 
ATOM   2122 H HH22 . ARG   A 1 137 ? 3.345   -63.879 105.342 1   117.407 ? 831  ARG   A HH22 1 c 
ATOM   2123 N N    . ARG   A 1 138 ? 9.546   -64.937 106.087 1   130.517 ? 832  ARG   A N    1 ? 
ATOM   2124 C CA   . ARG   A 1 138 ? 10.558  -64.187 105.349 1   138.03  ? 832  ARG   A CA   1 ? 
ATOM   2125 C C    . ARG   A 1 138 ? 10.415  -62.69  105.638 1   127.306 ? 832  ARG   A C    1 ? 
ATOM   2126 O O    . ARG   A 1 138 ? 11.107  -61.866 105.042 1   142.87  ? 832  ARG   A O    1 ? 
ATOM   2127 C CB   . ARG   A 1 138 ? 10.469  -64.446 103.839 1   129.961 ? 832  ARG   A CB   1 ? 
ATOM   2128 C CG   . ARG   A 1 138 ? 10.204  -65.907 103.508 1   126.653 ? 832  ARG   A CG   1 ? 
ATOM   2129 C CD   . ARG   A 1 138 ? 10.692  -66.28  102.138 1   134.901 ? 832  ARG   A CD   1 ? 
ATOM   2130 N NE   . ARG   A 1 138 ? 10.464  -67.704 101.879 1   143.351 ? 832  ARG   A NE   1 ? 
ATOM   2131 C CZ   . ARG   A 1 138 ? 10.861  -68.326 100.781 1   153.515 ? 832  ARG   A CZ   1 ? 
ATOM   2132 N NH1  . ARG   A 1 138 ? 11.578  -67.669 99.886  1   155.979 ? 832  ARG   A NH1  1 ? 
ATOM   2133 N NH2  . ARG   A 1 138 ? 10.551  -69.598 100.596 1   156.277 ? 832  ARG   A NH2  1 ? 
ATOM   2134 H H    . ARG   A 1 138 ? 9.754   -65.24  106.923 1   128.345 ? 832  ARG   A H    1 c 
ATOM   2135 H HA   . ARG   A 1 138 ? 11.449  -64.483 105.664 1   132.945 ? 832  ARG   A HA   1 c 
ATOM   2136 H HB2  . ARG   A 1 138 ? 9.759   -63.892 103.452 1   131.071 ? 832  ARG   A HB2  1 c 
ATOM   2137 H HB3  . ARG   A 1 138 ? 11.317  -64.177 103.425 1   131.036 ? 832  ARG   A HB3  1 c 
ATOM   2138 H HG2  . ARG   A 1 138 ? 10.651  -66.476 104.172 1   129.337 ? 832  ARG   A HG2  1 c 
ATOM   2139 H HG3  . ARG   A 1 138 ? 9.244   -66.089 103.553 1   129.384 ? 832  ARG   A HG3  1 c 
ATOM   2140 H HD2  . ARG   A 1 138 ? 10.221  -65.748 101.465 1   134.907 ? 832  ARG   A HD2  1 c 
ATOM   2141 H HD3  . ARG   A 1 138 ? 11.65   -66.086 102.067 1   134.964 ? 832  ARG   A HD3  1 c 
ATOM   2142 H HE   . ARG   A 1 138 ? 10.043  -68.169 102.484 1   143.721 ? 832  ARG   A HE   1 c 
ATOM   2143 H HH11 . ARG   A 1 138 ? 11.278  -66.903 99.552  1   155.078 ? 832  ARG   A HH11 1 c 
ATOM   2144 H HH12 . ARG   A 1 138 ? 12.358  -68.002 99.623  1   155.185 ? 832  ARG   A HH12 1 c 
ATOM   2145 H HH21 . ARG   A 1 138 ? 10.086  -70.035 101.208 1   155.222 ? 832  ARG   A HH21 1 c 
ATOM   2146 H HH22 . ARG   A 1 138 ? 10.813  -70.009 99.859  1   155.379 ? 832  ARG   A HH22 1 c 
ATOM   2147 N N    . LEU   A 1 139 ? 9.504   -62.355 106.561 1   127.58  ? 833  LEU   A N    1 ? 
ATOM   2148 C CA   . LEU   A 1 139 ? 9.351   -61     107.069 1   123.078 ? 833  LEU   A CA   1 ? 
ATOM   2149 C C    . LEU   A 1 139 ? 10.479  -60.702 108.056 1   110.042 ? 833  LEU   A C    1 ? 
ATOM   2150 O O    . LEU   A 1 139 ? 10.881  -61.582 108.813 1   111.377 ? 833  LEU   A O    1 ? 
ATOM   2151 C CB   . LEU   A 1 139 ? 7.981   -60.864 107.738 1   122.956 ? 833  LEU   A CB   1 ? 
ATOM   2152 C CG   . LEU   A 1 139 ? 7.323   -59.487 107.645 1   135.647 ? 833  LEU   A CG   1 ? 
ATOM   2153 C CD1  . LEU   A 1 139 ? 6.957   -59.163 106.197 1   148.585 ? 833  LEU   A CD1  1 ? 
ATOM   2154 C CD2  . LEU   A 1 139 ? 6.134   -59.461 108.566 1   138.362 ? 833  LEU   A CD2  1 ? 
ATOM   2155 H H    . LEU   A 1 139 ? 8.958   -63.004 106.9   1   126.516 ? 833  LEU   A H    1 c 
ATOM   2156 H HA   . LEU   A 1 139 ? 9.412   -60.371 106.308 1   121.536 ? 833  LEU   A HA   1 c 
ATOM   2157 H HB2  . LEU   A 1 139 ? 7.373   -61.524 107.333 1   125.907 ? 833  LEU   A HB2  1 c 
ATOM   2158 H HB3  . LEU   A 1 139 ? 8.081   -61.099 108.69  1   125.838 ? 833  LEU   A HB3  1 c 
ATOM   2159 H HG   . LEU   A 1 139 ? 7.974   -58.809 107.96  1   135.972 ? 833  LEU   A HG   1 c 
ATOM   2160 H HD11 . LEU   A 1 139 ? 7.765   -58.975 105.69  1   144.506 ? 833  LEU   A HD11 1 c 
ATOM   2161 H HD12 . LEU   A 1 139 ? 6.376   -58.384 106.175 1   144.596 ? 833  LEU   A HD12 1 c 
ATOM   2162 H HD13 . LEU   A 1 139 ? 6.495   -59.921 105.8   1   144.49  ? 833  LEU   A HD13 1 c 
ATOM   2163 H HD21 . LEU   A 1 139 ? 6.312   -60.013 109.347 1   137.253 ? 833  LEU   A HD21 1 c 
ATOM   2164 H HD22 . LEU   A 1 139 ? 5.353   -59.805 108.099 1   137.32  ? 833  LEU   A HD22 1 c 
ATOM   2165 H HD23 . LEU   A 1 139 ? 5.972   -58.549 108.85  1   137.148 ? 833  LEU   A HD23 1 c 
ATOM   2166 N N    . VAL   A 1 140 ? 10.964  -59.454 108.037 1   101.204 ? 834  VAL   A N    1 ? 
ATOM   2167 C CA   . VAL   A 1 140 ? 11.994  -58.984 108.946 1   95.365  ? 834  VAL   A CA   1 ? 
ATOM   2168 C C    . VAL   A 1 140 ? 11.398  -57.876 109.813 1   102.766 ? 834  VAL   A C    1 ? 
ATOM   2169 O O    . VAL   A 1 140 ? 10.864  -56.905 109.291 1   129.141 ? 834  VAL   A O    1 ? 
ATOM   2170 C CB   . VAL   A 1 140 ? 13.253  -58.501 108.189 1   99.09   ? 834  VAL   A CB   1 ? 
ATOM   2171 C CG1  . VAL   A 1 140 ? 14.356  -57.973 109.104 1   104.964 ? 834  VAL   A CG1  1 ? 
ATOM   2172 C CG2  . VAL   A 1 140 ? 13.815  -59.602 107.306 1   96.695  ? 834  VAL   A CG2  1 ? 
ATOM   2173 H H    . VAL   A 1 140 ? 10.631  -58.865 107.423 1   102.14  ? 834  VAL   A H    1 c 
ATOM   2174 H HA   . VAL   A 1 140 ? 12.253  -59.725 109.527 1   98.743  ? 834  VAL   A HA   1 c 
ATOM   2175 H HB   . VAL   A 1 140 ? 12.971  -57.761 107.602 1   98.996  ? 834  VAL   A HB   1 c 
ATOM   2176 H HG11 . VAL   A 1 140 ? 14.664  -58.688 109.684 1   103.195 ? 834  VAL   A HG11 1 c 
ATOM   2177 H HG12 . VAL   A 1 140 ? 14.013  -57.243 109.644 1   103.475 ? 834  VAL   A HG12 1 c 
ATOM   2178 H HG13 . VAL   A 1 140 ? 15.099  -57.654 108.565 1   103.252 ? 834  VAL   A HG13 1 c 
ATOM   2179 H HG21 . VAL   A 1 140 ? 14.622  -59.286 106.867 1   97.424  ? 834  VAL   A HG21 1 c 
ATOM   2180 H HG22 . VAL   A 1 140 ? 13.158  -59.848 106.633 1   97.439  ? 834  VAL   A HG22 1 c 
ATOM   2181 H HG23 . VAL   A 1 140 ? 14.026  -60.379 107.85  1   97.494  ? 834  VAL   A HG23 1 c 
ATOM   2182 N N    . HIS   A 1 141 ? 11.549  -58.009 111.138 1   106.842 ? 835  HIS   A N    1 ? 
ATOM   2183 C CA   . HIS   A 1 141 ? 11.028  -57.043 112.098 1   117.306 ? 835  HIS   A CA   1 ? 
ATOM   2184 C C    . HIS   A 1 141 ? 11.696  -55.673 111.926 1   115.084 ? 835  HIS   A C    1 ? 
ATOM   2185 O O    . HIS   A 1 141 ? 11.037  -54.627 111.959 1   115.863 ? 835  HIS   A O    1 ? 
ATOM   2186 C CB   . HIS   A 1 141 ? 11.166  -57.576 113.534 1   104.86  ? 835  HIS   A CB   1 ? 
ATOM   2187 C CG   . HIS   A 1 141 ? 10.33   -56.798 114.495 1   107.987 ? 835  HIS   A CG   1 ? 
ATOM   2188 N ND1  . HIS   A 1 141 ? 10.642  -55.509 114.857 1   109.862 ? 835  HIS   A ND1  1 ? 
ATOM   2189 C CD2  . HIS   A 1 141 ? 9.155   -57.07  115.066 1   110.706 ? 835  HIS   A CD2  1 ? 
ATOM   2190 C CE1  . HIS   A 1 141 ? 9.706   -55.053 115.671 1   122.686 ? 835  HIS   A CE1  1 ? 
ATOM   2191 N NE2  . HIS   A 1 141 ? 8.807   -55.991 115.819 1   118.284 ? 835  HIS   A NE2  1 ? 
ATOM   2192 H H    . HIS   A 1 141 ? 12.001  -58.736 111.458 1   107.914 ? 835  HIS   A H    1 c 
ATOM   2193 H HA   . HIS   A 1 141 ? 10.064  -56.937 111.906 1   112.428 ? 835  HIS   A HA   1 c 
ATOM   2194 H HB2  . HIS   A 1 141 ? 10.889  -58.517 113.553 1   108.263 ? 835  HIS   A HB2  1 c 
ATOM   2195 H HB3  . HIS   A 1 141 ? 12.108  -57.519 113.806 1   108.265 ? 835  HIS   A HB3  1 c 
ATOM   2196 H HD1  . HIS   A 1 141 ? 11.311  -55.015 114.556 0   111.41  ? 835  HIS   A HD1  1 c 
ATOM   2197 H HD2  . HIS   A 1 141 ? 8.68    -57.875 115.007 1   111.742 ? 835  HIS   A HD2  1 c 
ATOM   2198 H HE1  . HIS   A 1 141 ? 9.685   -54.207 116.077 1   118.191 ? 835  HIS   A HE1  1 c 
ATOM   2199 H HE2  . HIS   A 1 141 ? 8.07    -55.886 116.344 0   120.51  ? 835  HIS   A HE2  1 c 
ATOM   2200 N N    . ARG   A 1 142 ? 13.025  -55.702 111.793 1   115.412 ? 836  ARG   A N    1 ? 
ATOM   2201 C CA   . ARG   A 1 142 ? 13.838  -54.511 111.603 1   116.904 ? 836  ARG   A CA   1 ? 
ATOM   2202 C C    . ARG   A 1 142 ? 13.787  -53.613 112.834 1   104.099 ? 836  ARG   A C    1 ? 
ATOM   2203 O O    . ARG   A 1 142 ? 14.446  -52.584 112.856 1   119.596 ? 836  ARG   A O    1 ? 
ATOM   2204 C CB   . ARG   A 1 142 ? 13.469  -53.742 110.327 1   135.625 ? 836  ARG   A CB   1 ? 
ATOM   2205 C CG   . ARG   A 1 142 ? 13.868  -54.461 109.04  1   158.162 ? 836  ARG   A CG   1 ? 
ATOM   2206 C CD   . ARG   A 1 142 ? 14.117  -53.504 107.882 1   170.069 ? 836  ARG   A CD   1 ? 
ATOM   2207 N NE   . ARG   A 1 142 ? 13.066  -52.487 107.795 1   176.18  ? 836  ARG   A NE   1 ? 
ATOM   2208 C CZ   . ARG   A 1 142 ? 13.212  -51.27  107.297 1   165.387 ? 836  ARG   A CZ   1 ? 
ATOM   2209 N NH1  . ARG   A 1 142 ? 14.378  -50.884 106.814 1   152.857 ? 836  ARG   A NH1  1 ? 
ATOM   2210 N NH2  . ARG   A 1 142 ? 12.186  -50.437 107.299 1   163.369 ? 836  ARG   A NH2  1 ? 
ATOM   2211 H H    . ARG   A 1 142 ? 13.449  -56.51  111.831 1   115.521 ? 836  ARG   A H    1 c 
ATOM   2212 H HA   . ARG   A 1 142 ? 14.777  -54.81  111.495 1   117.521 ? 836  ARG   A HA   1 c 
ATOM   2213 H HB2  . ARG   A 1 142 ? 12.502  -53.584 110.313 1   135.591 ? 836  ARG   A HB2  1 c 
ATOM   2214 H HB3  . ARG   A 1 142 ? 13.912  -52.867 110.347 1   135.819 ? 836  ARG   A HB3  1 c 
ATOM   2215 H HG2  . ARG   A 1 142 ? 14.684  -54.983 109.202 1   154.733 ? 836  ARG   A HG2  1 c 
ATOM   2216 H HG3  . ARG   A 1 142 ? 13.156  -55.088 108.788 1   155.171 ? 836  ARG   A HG3  1 c 
ATOM   2217 H HD2  . ARG   A 1 142 ? 14.982  -53.066 108.008 1   168.068 ? 836  ARG   A HD2  1 c 
ATOM   2218 H HD3  . ARG   A 1 142 ? 14.15   -54.009 107.044 1   168.592 ? 836  ARG   A HD3  1 c 
ATOM   2219 H HE   . ARG   A 1 142 ? 12.274  -52.703 108.088 1   171.689 ? 836  ARG   A HE   1 c 
ATOM   2220 H HH11 . ARG   A 1 142 ? 14.784  -51.372 106.197 1   156.683 ? 836  ARG   A HH11 1 c 
ATOM   2221 H HH12 . ARG   A 1 142 ? 14.748  -50.135 107.108 1   156.624 ? 836  ARG   A HH12 1 c 
ATOM   2222 H HH21 . ARG   A 1 142 ? 11.431  -50.663 107.7   1   164.123 ? 836  ARG   A HH21 1 c 
ATOM   2223 H HH22 . ARG   A 1 142 ? 12.259  -49.653 106.898 1   163.936 ? 836  ARG   A HH22 1 c 
ATOM   2224 N N    . ASP   A 1 143 ? 13.03   -53.992 113.864 1   94.186  ? 837  ASP   A N    1 ? 
ATOM   2225 C CA   . ASP   A 1 143 ? 12.921  -53.147 115.038 1   102.484 ? 837  ASP   A CA   1 ? 
ATOM   2226 C C    . ASP   A 1 143 ? 12.475  -53.974 116.234 1   104.397 ? 837  ASP   A C    1 ? 
ATOM   2227 O O    . ASP   A 1 143 ? 11.424  -53.724 116.813 1   104.571 ? 837  ASP   A O    1 ? 
ATOM   2228 C CB   . ASP   A 1 143 ? 11.989  -51.959 114.863 1   103.374 ? 837  ASP   A CB   1 ? 
ATOM   2229 C CG   . ASP   A 1 143 ? 12.086  -50.96  116.011 1   111.197 ? 837  ASP   A CG   1 ? 
ATOM   2230 O OD1  . ASP   A 1 143 ? 13.154  -50.919 116.676 1   119.375 ? 837  ASP   A OD1  1 ? 
ATOM   2231 O OD2  . ASP   A 1 143 ? 11.086  -50.274 116.282 1   109.888 ? 837  ASP   A OD2  1 ? 
ATOM   2232 H H    . ASP   A 1 143 ? 12.607  -54.8   113.856 1   98.793  ? 837  ASP   A H    1 c 
ATOM   2233 H HA   . ASP   A 1 143 ? 13.816  -52.79  115.236 1   101.58  ? 837  ASP   A HA   1 c 
ATOM   2234 H HB2  . ASP   A 1 143 ? 12.217  -51.493 114.031 1   104.901 ? 837  ASP   A HB2  1 c 
ATOM   2235 H HB3  . ASP   A 1 143 ? 11.062  -52.271 114.791 1   104.896 ? 837  ASP   A HB3  1 c 
ATOM   2236 N N    . LEU   A 1 144 ? 13.312  -54.928 116.631 1   112.748 ? 838  LEU   A N    1 ? 
ATOM   2237 C CA   . LEU   A 1 144 ? 12.973  -55.755 117.766 1   100.604 ? 838  LEU   A CA   1 ? 
ATOM   2238 C C    . LEU   A 1 144 ? 13.595  -55.16  119.015 1   99.155  ? 838  LEU   A C    1 ? 
ATOM   2239 O O    . LEU   A 1 144 ? 14.797  -54.941 119.055 1   109.773 ? 838  LEU   A O    1 ? 
ATOM   2240 C CB   . LEU   A 1 144 ? 13.437  -57.184 117.556 1   99.952  ? 838  LEU   A CB   1 ? 
ATOM   2241 C CG   . LEU   A 1 144 ? 13.142  -58.095 118.742 1   100.82  ? 838  LEU   A CG   1 ? 
ATOM   2242 C CD1  . LEU   A 1 144 ? 11.649  -58.131 119.003 1   102.87  ? 838  LEU   A CD1  1 ? 
ATOM   2243 C CD2  . LEU   A 1 144 ? 13.685  -59.484 118.495 1   104.194 ? 838  LEU   A CD2  1 ? 
ATOM   2244 H H    . LEU   A 1 144 ? 14.101  -55.067 116.191 1   107.849 ? 838  LEU   A H    1 c 
ATOM   2245 H HA   . LEU   A 1 144 ? 11.988  -55.751 117.868 1   102.505 ? 838  LEU   A HA   1 c 
ATOM   2246 H HB2  . LEU   A 1 144 ? 12.984  -57.545 116.759 1   100.312 ? 838  LEU   A HB2  1 c 
ATOM   2247 H HB3  . LEU   A 1 144 ? 14.409  -57.177 117.396 1   100.371 ? 838  LEU   A HB3  1 c 
ATOM   2248 H HG   . LEU   A 1 144 ? 13.592  -57.725 119.544 1   101.587 ? 838  LEU   A HG   1 c 
ATOM   2249 H HD11 . LEU   A 1 144 ? 11.37   -57.301 119.426 1   102.259 ? 838  LEU   A HD11 1 c 
ATOM   2250 H HD12 . LEU   A 1 144 ? 11.44   -58.877 119.592 1   102.267 ? 838  LEU   A HD12 1 c 
ATOM   2251 H HD13 . LEU   A 1 144 ? 11.174  -58.241 118.162 1   102.248 ? 838  LEU   A HD13 1 c 
ATOM   2252 H HD21 . LEU   A 1 144 ? 14.628  -59.429 118.269 1   103.176 ? 838  LEU   A HD21 1 c 
ATOM   2253 H HD22 . LEU   A 1 144 ? 13.2    -59.897 117.761 1   103.184 ? 838  LEU   A HD22 1 c 
ATOM   2254 H HD23 . LEU   A 1 144 ? 13.576  -60.023 119.297 1   103.18  ? 838  LEU   A HD23 1 c 
ATOM   2255 N N    . ALA   A 1 145 ? 12.747  -54.938 120.014 1   104.219 ? 839  ALA   A N    1 ? 
ATOM   2256 C CA   . ALA   A 1 145 ? 13.146  -54.389 121.291 1   104.946 ? 839  ALA   A CA   1 ? 
ATOM   2257 C C    . ALA   A 1 145 ? 12.137  -54.85  122.33  1   100.422 ? 839  ALA   A C    1 ? 
ATOM   2258 O O    . ALA   A 1 145 ? 11.063  -55.319 121.98  1   96.104  ? 839  ALA   A O    1 ? 
ATOM   2259 C CB   . ALA   A 1 145 ? 13.19   -52.893 121.21  1   103.94  ? 839  ALA   A CB   1 ? 
ATOM   2260 H H    . ALA   A 1 145 ? 11.863  -55.134 119.888 1   103.105 ? 839  ALA   A H    1 c 
ATOM   2261 H HA   . ALA   A 1 145 ? 14.045  -54.743 121.533 1   103.709 ? 839  ALA   A HA   1 c 
ATOM   2262 H HB1  . ALA   A 1 145 ? 13.827  -52.621 120.527 1   104.24  ? 839  ALA   A HB1  1 c 
ATOM   2263 H HB2  . ALA   A 1 145 ? 12.309  -52.551 120.982 1   104.24  ? 839  ALA   A HB2  1 c 
ATOM   2264 H HB3  . ALA   A 1 145 ? 13.464  -52.527 122.068 1   104.24  ? 839  ALA   A HB3  1 c 
ATOM   2265 N N    . ALA   A 1 146 ? 12.501  -54.721 123.603 1   106.572 ? 840  ALA   A N    1 ? 
ATOM   2266 C CA   . ALA   A 1 146 ? 11.605  -55.065 124.686 1   105.157 ? 840  ALA   A CA   1 ? 
ATOM   2267 C C    . ALA   A 1 146 ? 10.34   -54.213 124.602 1   100.699 ? 840  ALA   A C    1 ? 
ATOM   2268 O O    . ALA   A 1 146 ? 9.27    -54.668 124.995 1   94.642  ? 840  ALA   A O    1 ? 
ATOM   2269 C CB   . ALA   A 1 146 ? 12.325  -54.876 125.998 1   115.577 ? 840  ALA   A CB   1 ? 
ATOM   2270 H H    . ALA   A 1 146 ? 13.336  -54.408 123.802 1   104.831 ? 840  ALA   A H    1 c 
ATOM   2271 H HA   . ALA   A 1 146 ? 11.346  -56.023 124.587 1   106.373 ? 840  ALA   A HA   1 c 
ATOM   2272 H HB1  . ALA   A 1 146 ? 13.119  -55.436 126.018 1   112.374 ? 840  ALA   A HB1  1 c 
ATOM   2273 H HB2  . ALA   A 1 146 ? 12.586  -53.945 126.096 1   112.374 ? 840  ALA   A HB2  1 c 
ATOM   2274 H HB3  . ALA   A 1 146 ? 11.738  -55.124 126.732 1   112.374 ? 840  ALA   A HB3  1 c 
ATOM   2275 N N    . ARG   A 1 147 ? 10.491  -52.978 124.096 1   104.264 ? 841  ARG   A N    1 ? 
ATOM   2276 C CA   . ARG   A 1 147 ? 9.381   -52.053 123.933 1   97.498  ? 841  ARG   A CA   1 ? 
ATOM   2277 C C    . ARG   A 1 147 ? 8.36    -52.592 122.925 1   95.159  ? 841  ARG   A C    1 ? 
ATOM   2278 O O    . ARG   A 1 147 ? 7.184   -52.283 123.021 1   101.65  ? 841  ARG   A O    1 ? 
ATOM   2279 C CB   . ARG   A 1 147 ? 9.846   -50.66  123.495 1   94.996  ? 841  ARG   A CB   1 ? 
ATOM   2280 C CG   . ARG   A 1 147 ? 9.84    -50.446 121.988 1   102.533 ? 841  ARG   A CG   1 ? 
ATOM   2281 C CD   . ARG   A 1 147 ? 10.401  -49.106 121.56  1   100.729 ? 841  ARG   A CD   1 ? 
ATOM   2282 N NE   . ARG   A 1 147 ? 11.847  -49.226 121.341 1   116.239 ? 841  ARG   A NE   1 ? 
ATOM   2283 C CZ   . ARG   A 1 147 ? 12.425  -49.32  120.144 1   127.718 ? 841  ARG   A CZ   1 ? 
ATOM   2284 N NH1  . ARG   A 1 147 ? 11.657  -49.309 119.061 1   130.811 ? 841  ARG   A NH1  1 ? 
ATOM   2285 N NH2  . ARG   A 1 147 ? 13.754  -49.422 120.042 1   105.1   ? 841  ARG   A NH2  1 ? 
ATOM   2286 H H    . ARG   A 1 147 ? 11.327  -52.696 123.858 1   101.809 ? 841  ARG   A H    1 c 
ATOM   2287 H HA   . ARG   A 1 147 ? 8.933   -51.963 124.808 1   97.971  ? 841  ARG   A HA   1 c 
ATOM   2288 H HB2  . ARG   A 1 147 ? 9.262   -49.989 123.91  1   97.253  ? 841  ARG   A HB2  1 c 
ATOM   2289 H HB3  . ARG   A 1 147 ? 10.755  -50.51  123.831 1   97.311  ? 841  ARG   A HB3  1 c 
ATOM   2290 H HG2  . ARG   A 1 147 ? 10.364  -51.159 121.562 1   100.419 ? 841  ARG   A HG2  1 c 
ATOM   2291 H HG3  . ARG   A 1 147 ? 8.918   -50.517 121.657 1   100.341 ? 841  ARG   A HG3  1 c 
ATOM   2292 H HD2  . ARG   A 1 147 ? 9.965   -48.807 120.737 1   104.983 ? 841  ARG   A HD2  1 c 
ATOM   2293 H HD3  . ARG   A 1 147 ? 10.233  -48.439 122.257 1   104.621 ? 841  ARG   A HD3  1 c 
ATOM   2294 H HE   . ARG   A 1 147 ? 12.366  -49.238 122.041 1   114.909 ? 841  ARG   A HE   1 c 
ATOM   2295 H HH11 . ARG   A 1 147 ? 11.049  -49.94  118.947 1   129.058 ? 841  ARG   A HH11 1 c 
ATOM   2296 H HH12 . ARG   A 1 147 ? 11.758  -48.671 118.458 1   129.664 ? 841  ARG   A HH12 1 c 
ATOM   2297 H HH21 . ARG   A 1 147 ? 14.273  -48.962 120.59  1   111.667 ? 841  ARG   A HH21 1 c 
ATOM   2298 H HH22 . ARG   A 1 147 ? 14.108  -49.949 119.426 1   111.901 ? 841  ARG   A HH22 1 c 
ATOM   2299 N N    . ASN   A 1 148 ? 8.803   -53.391 121.951 1   99.038  ? 842  ASN   A N    1 ? 
ATOM   2300 C CA   . ASN   A 1 148 ? 7.939   -53.895 120.889 1   96.529  ? 842  ASN   A CA   1 ? 
ATOM   2301 C C    . ASN   A 1 148 ? 7.445   -55.318 121.163 1   98.014  ? 842  ASN   A C    1 ? 
ATOM   2302 O O    . ASN   A 1 148 ? 6.988   -56.01  120.241 1   100.59  ? 842  ASN   A O    1 ? 
ATOM   2303 C CB   . ASN   A 1 148 ? 8.665   -53.875 119.547 1   100.868 ? 842  ASN   A CB   1 ? 
ATOM   2304 C CG   . ASN   A 1 148 ? 8.792   -52.47  119.022 1   101.91  ? 842  ASN   A CG   1 ? 
ATOM   2305 O OD1  . ASN   A 1 148 ? 7.929   -51.624 119.316 1   98.053  ? 842  ASN   A OD1  1 ? 
ATOM   2306 N ND2  . ASN   A 1 148 ? 9.832   -52.231 118.231 1   106.286 ? 842  ASN   A ND2  1 ? 
ATOM   2307 H H    . ASN   A 1 148 ? 9.686   -53.623 121.936 1   97.633  ? 842  ASN   A H    1 c 
ATOM   2308 H HA   . ASN   A 1 148 ? 7.156   -53.305 120.816 1   98.101  ? 842  ASN   A HA   1 c 
ATOM   2309 H HB2  . ASN   A 1 148 ? 9.556   -54.264 119.655 1   100.156 ? 842  ASN   A HB2  1 c 
ATOM   2310 H HB3  . ASN   A 1 148 ? 8.171   -54.415 118.899 1   100.11  ? 842  ASN   A HB3  1 c 
ATOM   2311 H HD21 . ASN   A 1 148 ? 9.82    -51.524 117.694 1   105.115 ? 842  ASN   A HD21 1 c 
ATOM   2312 H HD22 . ASN   A 1 148 ? 10.534  -52.773 118.236 1   104.897 ? 842  ASN   A HD22 1 c 
ATOM   2313 N N    . VAL   A 1 149 ? 7.58    -55.768 122.414 1   99.431  ? 843  VAL   A N    1 ? 
ATOM   2314 C CA   . VAL   A 1 149 ? 6.972   -57.013 122.842 1   93.056  ? 843  VAL   A CA   1 ? 
ATOM   2315 C C    . VAL   A 1 149 ? 5.878   -56.652 123.827 1   88.298  ? 843  VAL   A C    1 ? 
ATOM   2316 O O    . VAL   A 1 149 ? 6.124   -55.879 124.745 1   109.873 ? 843  VAL   A O    1 ? 
ATOM   2317 C CB   . VAL   A 1 149 ? 7.957   -58     123.486 1   92.556  ? 843  VAL   A CB   1 ? 
ATOM   2318 C CG1  . VAL   A 1 149 ? 7.259   -59.304 123.833 1   99.182  ? 843  VAL   A CG1  1 ? 
ATOM   2319 C CG2  . VAL   A 1 149 ? 9.15    -58.283 122.591 1   97.574  ? 843  VAL   A CG2  1 ? 
ATOM   2320 H H    . VAL   A 1 149 ? 8.074   -55.292 123.018 1   97.605  ? 843  VAL   A H    1 c 
ATOM   2321 H HA   . VAL   A 1 149 ? 6.565   -57.445 122.066 1   93.253  ? 843  VAL   A HA   1 c 
ATOM   2322 H HB   . VAL   A 1 149 ? 8.284   -57.59  124.321 1   94.738  ? 843  VAL   A HB   1 c 
ATOM   2323 H HG11 . VAL   A 1 149 ? 6.782   -59.635 123.053 1   97.146  ? 843  VAL   A HG11 1 c 
ATOM   2324 H HG12 . VAL   A 1 149 ? 6.63    -59.154 124.557 1   97.058  ? 843  VAL   A HG12 1 c 
ATOM   2325 H HG13 . VAL   A 1 149 ? 7.919   -59.962 124.11  1   97.142  ? 843  VAL   A HG13 1 c 
ATOM   2326 H HG21 . VAL   A 1 149 ? 9.728   -58.939 123.016 1   96.074  ? 843  VAL   A HG21 1 c 
ATOM   2327 H HG22 . VAL   A 1 149 ? 9.648   -57.463 122.443 1   96.082  ? 843  VAL   A HG22 1 c 
ATOM   2328 H HG23 . VAL   A 1 149 ? 8.841   -58.632 121.738 1   96.068  ? 843  VAL   A HG23 1 c 
ATOM   2329 N N    . LEU   A 1 150 ? 4.685   -57.222 123.63  1   88.205  ? 844  LEU   A N    1 ? 
ATOM   2330 C CA   . LEU   A 1 150 ? 3.535   -56.901 124.455 1   100.827 ? 844  LEU   A CA   1 ? 
ATOM   2331 C C    . LEU   A 1 150 ? 3.098   -58.15  125.202 1   92.098  ? 844  LEU   A C    1 ? 
ATOM   2332 O O    . LEU   A 1 150 ? 3.197   -59.242 124.655 1   93.962  ? 844  LEU   A O    1 ? 
ATOM   2333 C CB   . LEU   A 1 150 ? 2.396   -56.358 123.593 1   115.064 ? 844  LEU   A CB   1 ? 
ATOM   2334 C CG   . LEU   A 1 150 ? 2.638   -55.014 122.901 1   122.953 ? 844  LEU   A CG   1 ? 
ATOM   2335 C CD1  . LEU   A 1 150 ? 1.301   -54.415 122.544 1   125.524 ? 844  LEU   A CD1  1 ? 
ATOM   2336 C CD2  . LEU   A 1 150 ? 3.473   -54.065 123.761 1   138.42  ? 844  LEU   A CD2  1 ? 
ATOM   2337 H H    . LEU   A 1 150 ? 4.586   -57.834 122.959 1   90.968  ? 844  LEU   A H    1 c 
ATOM   2338 H HA   . LEU   A 1 150 ? 3.8     -56.217 125.119 1   99.224  ? 844  LEU   A HA   1 c 
ATOM   2339 H HB2  . LEU   A 1 150 ? 2.191   -57.029 122.901 1   113.227 ? 844  LEU   A HB2  1 c 
ATOM   2340 H HB3  . LEU   A 1 150 ? 1.598   -56.272 124.165 1   113.199 ? 844  LEU   A HB3  1 c 
ATOM   2341 H HG   . LEU   A 1 150 ? 3.134   -55.184 122.059 1   124.634 ? 844  LEU   A HG   1 c 
ATOM   2342 H HD11 . LEU   A 1 150 ? 0.796   -55.045 122.003 1   124.751 ? 844  LEU   A HD11 1 c 
ATOM   2343 H HD12 . LEU   A 1 150 ? 1.438   -53.595 122.041 1   124.811 ? 844  LEU   A HD12 1 c 
ATOM   2344 H HD13 . LEU   A 1 150 ? 0.805   -54.216 123.356 1   124.686 ? 844  LEU   A HD13 1 c 
ATOM   2345 H HD21 . LEU   A 1 150 ? 4.405   -54.333 123.732 1   132.868 ? 844  LEU   A HD21 1 c 
ATOM   2346 H HD22 . LEU   A 1 150 ? 3.155   -54.093 124.678 1   132.808 ? 844  LEU   A HD22 1 c 
ATOM   2347 H HD23 . LEU   A 1 150 ? 3.389   -53.16  123.418 1   133.308 ? 844  LEU   A HD23 1 c 
ATOM   2348 N N    . VAL   A 1 151 ? 2.561   -57.968 126.415 1   90.727  ? 845  VAL   A N    1 ? 
ATOM   2349 C CA   . VAL   A 1 151 ? 2.214   -59.103 127.258 1   96.367  ? 845  VAL   A CA   1 ? 
ATOM   2350 C C    . VAL   A 1 151 ? 0.696   -59.208 127.393 1   87.043  ? 845  VAL   A C    1 ? 
ATOM   2351 O O    . VAL   A 1 151 ? 0.063   -58.337 127.975 1   84.671  ? 845  VAL   A O    1 ? 
ATOM   2352 C CB   . VAL   A 1 151 ? 2.93    -59.029 128.623 1   100.128 ? 845  VAL   A CB   1 ? 
ATOM   2353 C CG1  . VAL   A 1 151 ? 3.778   -57.775 128.764 1   89.278  ? 845  VAL   A CG1  1 ? 
ATOM   2354 C CG2  . VAL   A 1 151 ? 1.981   -59.165 129.802 1   102.249 ? 845  VAL   A CG2  1 ? 
ATOM   2355 H H    . VAL   A 1 151 ? 2.382   -57.122 126.71  1   92.38   ? 845  VAL   A H    1 c 
ATOM   2356 H HA   . VAL   A 1 151 ? 2.528   -59.91  126.811 1   94.008  ? 845  VAL   A HA   1 c 
ATOM   2357 H HB   . VAL   A 1 151 ? 3.544   -59.797 128.663 1   97.604  ? 845  VAL   A HB   1 c 
ATOM   2358 H HG11 . VAL   A 1 151 ? 3.2     -57     128.853 1   92.338  ? 845  VAL   A HG11 1 c 
ATOM   2359 H HG12 . VAL   A 1 151 ? 4.344   -57.671 127.98  1   92.335  ? 845  VAL   A HG12 1 c 
ATOM   2360 H HG13 . VAL   A 1 151 ? 4.337   -57.851 129.556 1   92.348  ? 845  VAL   A HG13 1 c 
ATOM   2361 H HG21 . VAL   A 1 151 ? 2.493   -59.318 130.614 1   101.497 ? 845  VAL   A HG21 1 c 
ATOM   2362 H HG22 . VAL   A 1 151 ? 1.376   -59.911 129.657 1   101.286 ? 845  VAL   A HG22 1 c 
ATOM   2363 H HG23 . VAL   A 1 151 ? 1.476   -58.349 129.893 1   101.324 ? 845  VAL   A HG23 1 c 
ATOM   2364 N N    . LYS   A 1 152 ? 0.133   -60.3   126.859 1   92.017  ? 846  LYS   A N    1 ? 
ATOM   2365 C CA   . LYS   A 1 152 ? -1.279  -60.62  127.002 1   85.909  ? 846  LYS   A CA   1 ? 
ATOM   2366 C C    . LYS   A 1 152 ? -1.548  -61.127 128.412 1   90.947  ? 846  LYS   A C    1 ? 
ATOM   2367 O O    . LYS   A 1 152 ? -2.485  -60.648 129.032 1   90.758  ? 846  LYS   A O    1 ? 
ATOM   2368 C CB   . LYS   A 1 152 ? -1.724  -61.61  125.917 1   83.109  ? 846  LYS   A CB   1 ? 
ATOM   2369 C CG   . LYS   A 1 152 ? -2.527  -62.798 126.372 1   82.2    ? 846  LYS   A CG   1 ? 
ATOM   2370 C CD   . LYS   A 1 152 ? -3.271  -63.506 125.248 1   84.723  ? 846  LYS   A CD   1 ? 
ATOM   2371 C CE   . LYS   A 1 152 ? -3.93   -64.768 125.71  1   96.362  ? 846  LYS   A CE   1 ? 
ATOM   2372 N NZ   . LYS   A 1 152 ? -4.67   -65.445 124.642 1   106.585 ? 846  LYS   A NZ   1 ? 
ATOM   2373 H H    . LYS   A 1 152 ? 0.661   -60.874 126.383 1   89.519  ? 846  LYS   A H    1 c 
ATOM   2374 H HA   . LYS   A 1 152 ? -1.793  -59.785 126.871 1   87.51   ? 846  LYS   A HA   1 c 
ATOM   2375 H HB2  . LYS   A 1 152 ? -2.258  -61.119 125.257 1   83.572  ? 846  LYS   A HB2  1 c 
ATOM   2376 H HB3  . LYS   A 1 152 ? -0.926  -61.944 125.454 1   83.753  ? 846  LYS   A HB3  1 c 
ATOM   2377 H HG2  . LYS   A 1 152 ? -1.919  -63.439 126.801 1   83.197  ? 846  LYS   A HG2  1 c 
ATOM   2378 H HG3  . LYS   A 1 152 ? -3.177  -62.501 127.045 1   83.061  ? 846  LYS   A HG3  1 c 
ATOM   2379 H HD2  . LYS   A 1 152 ? -3.955  -62.901 124.886 1   86.688  ? 846  LYS   A HD2  1 c 
ATOM   2380 H HD3  . LYS   A 1 152 ? -2.639  -63.718 124.528 1   86.688  ? 846  LYS   A HD3  1 c 
ATOM   2381 H HE2  . LYS   A 1 152 ? -3.251  -65.375 126.056 1   95.81   ? 846  LYS   A HE2  1 c 
ATOM   2382 H HE3  . LYS   A 1 152 ? -4.545  -64.561 126.436 1   95.81   ? 846  LYS   A HE3  1 c 
ATOM   2383 H HZ1  . LYS   A 1 152 ? -4.092  -65.744 124.012 1   103.343 ? 846  LYS   A HZ1  1 c 
ATOM   2384 H HZ2  . LYS   A 1 152 ? -5.254  -64.868 124.26  1   103.402 ? 846  LYS   A HZ2  1 c 
ATOM   2385 H HZ3  . LYS   A 1 152 ? -5.127  -66.149 124.985 1   103.343 ? 846  LYS   A HZ3  1 c 
ATOM   2386 N N    . THR   A 1 153 ? -0.785  -62.139 128.863 1   100.783 ? 847  THR   A N    1 ? 
ATOM   2387 C CA   . THR   A 1 153 ? -0.755  -62.574 130.256 1   87.753  ? 847  THR   A CA   1 ? 
ATOM   2388 C C    . THR   A 1 153 ? 0.703   -62.539 130.68  1   90.322  ? 847  THR   A C    1 ? 
ATOM   2389 O O    . THR   A 1 153 ? 1.582   -62.49  129.823 1   96.982  ? 847  THR   A O    1 ? 
ATOM   2390 C CB   . THR   A 1 153 ? -1.357  -63.965 130.466 1   84.825  ? 847  THR   A CB   1 ? 
ATOM   2391 O OG1  . THR   A 1 153 ? -0.43   -64.967 130.083 1   98.939  ? 847  THR   A OG1  1 ? 
ATOM   2392 C CG2  . THR   A 1 153 ? -2.608  -64.221 129.647 1   86.684  ? 847  THR   A CG2  1 ? 
ATOM   2393 H H    . THR   A 1 153 ? -0.256  -62.582 128.263 1   95.1    ? 847  THR   A H    1 c 
ATOM   2394 H HA   . THR   A 1 153 ? -1.26   -61.929 130.795 1   90.304  ? 847  THR   A HA   1 c 
ATOM   2395 H HB   . THR   A 1 153 ? -1.579  -64.078 131.421 1   88.779  ? 847  THR   A HB   1 c 
ATOM   2396 H HG1  . THR   A 1 153 ? -0.244  -64.864 129.259 0   97.81   ? 847  THR   A HG1  1 c 
ATOM   2397 H HG21 . THR   A 1 153 ? -3.064  -65.008 129.99  1   86.154  ? 847  THR   A HG21 1 c 
ATOM   2398 H HG22 . THR   A 1 153 ? -2.364  -64.368 128.719 1   86.231  ? 847  THR   A HG22 1 c 
ATOM   2399 H HG23 . THR   A 1 153 ? -3.199  -63.452 129.709 1   86.154  ? 847  THR   A HG23 1 c 
ATOM   2400 N N    . PRO   A 1 154 ? 1.02    -62.501 131.991 1   102.846 ? 848  PRO   A N    1 ? 
ATOM   2401 C CA   . PRO   A 1 154 ? 2.409   -62.544 132.409 1   100.994 ? 848  PRO   A CA   1 ? 
ATOM   2402 C C    . PRO   A 1 154 ? 3.138   -63.759 131.865 1   91.211  ? 848  PRO   A C    1 ? 
ATOM   2403 O O    . PRO   A 1 154 ? 4.351   -63.768 131.851 1   90.917  ? 848  PRO   A O    1 ? 
ATOM   2404 C CB   . PRO   A 1 154 ? 2.342   -62.546 133.927 1   102.447 ? 848  PRO   A CB   1 ? 
ATOM   2405 C CG   . PRO   A 1 154 ? 1.025   -61.851 134.219 1   116.126 ? 848  PRO   A CG   1 ? 
ATOM   2406 C CD   . PRO   A 1 154 ? 0.1     -62.295 133.119 1   113.08  ? 848  PRO   A CD   1 ? 
ATOM   2407 H HA   . PRO   A 1 154 ? 2.863   -61.73  132.105 1   99.731  ? 848  PRO   A HA   1 c 
ATOM   2408 H HB2  . PRO   A 1 154 ? 2.342   -63.459 134.277 1   104.981 ? 848  PRO   A HB2  1 c 
ATOM   2409 H HB3  . PRO   A 1 154 ? 3.092   -62.054 134.312 1   105.118 ? 848  PRO   A HB3  1 c 
ATOM   2410 H HG2  . PRO   A 1 154 ? 0.676   -62.119 135.092 1   112.216 ? 848  PRO   A HG2  1 c 
ATOM   2411 H HG3  . PRO   A 1 154 ? 1.134   -60.88  134.206 1   112.261 ? 848  PRO   A HG3  1 c 
ATOM   2412 H HD2  . PRO   A 1 154 ? -0.36   -63.123 133.35  1   111.509 ? 848  PRO   A HD2  1 c 
ATOM   2413 H HD3  . PRO   A 1 154 ? -0.558  -61.606 132.91  1   110.934 ? 848  PRO   A HD3  1 c 
ATOM   2414 N N    . GLN   A 1 155 ? 2.391   -64.774 131.422 1   96.086  ? 849  GLN   A N    1 ? 
ATOM   2415 C CA   . GLN   A 1 155 ? 2.956   -66.022 130.922 1   94.133  ? 849  GLN   A CA   1 ? 
ATOM   2416 C C    . GLN   A 1 155 ? 2.818   -66.113 129.397 1   84.215  ? 849  GLN   A C    1 ? 
ATOM   2417 O O    . GLN   A 1 155 ? 2.989   -67.187 128.829 1   84.198  ? 849  GLN   A O    1 ? 
ATOM   2418 C CB   . GLN   A 1 155 ? 2.319   -67.239 131.618 1   103.473 ? 849  GLN   A CB   1 ? 
ATOM   2419 C CG   . GLN   A 1 155 ? 0.836   -67.123 131.978 1   111.314 ? 849  GLN   A CG   1 ? 
ATOM   2420 C CD   . GLN   A 1 155 ? 0.563   -66.344 133.251 1   124.195 ? 849  GLN   A CD   1 ? 
ATOM   2421 O OE1  . GLN   A 1 155 ? 1.392   -66.236 134.158 1   121.249 ? 849  GLN   A OE1  1 ? 
ATOM   2422 N NE2  . GLN   A 1 155 ? -0.634  -65.794 133.349 1   145.475 ? 849  GLN   A NE2  1 ? 
ATOM   2423 H H    . GLN   A 1 155 ? 1.483   -64.685 131.424 1   94.92   ? 849  GLN   A H    1 c 
ATOM   2424 H HA   . GLN   A 1 155 ? 3.922   -66.031 131.141 1   94.18   ? 849  GLN   A HA   1 c 
ATOM   2425 H HB2  . GLN   A 1 155 ? 2.435   -68.02  131.038 1   102.777 ? 849  GLN   A HB2  1 c 
ATOM   2426 H HB3  . GLN   A 1 155 ? 2.824   -67.415 132.439 1   103.195 ? 849  GLN   A HB3  1 c 
ATOM   2427 H HG2  . GLN   A 1 155 ? 0.36    -66.696 131.239 1   112.196 ? 849  GLN   A HG2  1 c 
ATOM   2428 H HG3  . GLN   A 1 155 ? 0.463   -68.024 132.084 1   112.269 ? 849  GLN   A HG3  1 c 
ATOM   2429 H HE21 . GLN   A 1 155 ? -0.82   -65.261 134.032 1   137.921 ? 849  GLN   A HE21 1 c 
ATOM   2430 H HE22 . GLN   A 1 155 ? -1.254  -65.965 132.738 1   137.472 ? 849  GLN   A HE22 1 c 
ATOM   2431 N N    . HIS   A 1 156 ? 2.502   -65.005 128.711 1   87.485  ? 850  HIS   A N    1 ? 
ATOM   2432 C CA   . HIS   A 1 156 ? 2.258   -65.062 127.273 1   84.509  ? 850  HIS   A CA   1 ? 
ATOM   2433 C C    . HIS   A 1 156 ? 2.462   -63.702 126.609 1   82.261  ? 850  HIS   A C    1 ? 
ATOM   2434 O O    . HIS   A 1 156 ? 1.604   -62.837 126.683 1   87.697  ? 850  HIS   A O    1 ? 
ATOM   2435 C CB   . HIS   A 1 156 ? 0.851   -65.583 126.967 1   89.22   ? 850  HIS   A CB   1 ? 
ATOM   2436 C CG   . HIS   A 1 156 ? 0.612   -65.844 125.526 1   95.022  ? 850  HIS   A CG   1 ? 
ATOM   2437 N ND1  . HIS   A 1 156 ? -0.521  -66.484 125.085 1   104.46  ? 850  HIS   A ND1  1 ? 
ATOM   2438 C CD2  . HIS   A 1 156 ? 1.309   -65.544 124.433 1   103.459 ? 850  HIS   A CD2  1 ? 
ATOM   2439 C CE1  . HIS   A 1 156 ? -0.485  -66.568 123.761 1   112.699 ? 850  HIS   A CE1  1 ? 
ATOM   2440 N NE2  . HIS   A 1 156 ? 0.621   -66.005 123.344 1   102.253 ? 850  HIS   A NE2  1 ? 
ATOM   2441 H H    . HIS   A 1 156 ? 2.446   -64.2   129.139 1   86.12   ? 850  HIS   A H    1 c 
ATOM   2442 H HA   . HIS   A 1 156 ? 2.907   -65.695 126.882 1   85.551  ? 850  HIS   A HA   1 c 
ATOM   2443 H HB2  . HIS   A 1 156 ? 0.708   -66.415 127.468 1   89.418  ? 850  HIS   A HB2  1 c 
ATOM   2444 H HB3  . HIS   A 1 156 ? 0.194   -64.926 127.286 1   89.429  ? 850  HIS   A HB3  1 c 
ATOM   2445 H HD1  . HIS   A 1 156 ? -1.191  -66.784 125.598 0   104.57  ? 850  HIS   A HD1  1 c 
ATOM   2446 H HD2  . HIS   A 1 156 ? 2.135   -65.106 124.397 1   100.764 ? 850  HIS   A HD2  1 c 
ATOM   2447 H HE1  . HIS   A 1 156 ? -1.141  -66.968 123.217 1   108.085 ? 850  HIS   A HE1  1 c 
ATOM   2448 H HE2  . HIS   A 1 156 ? 0.873   -65.904 122.508 0   102.07  ? 850  HIS   A HE2  1 c 
ATOM   2449 N N    . VAL   A 1 157 ? 3.574   -63.551 125.882 1   87.217  ? 851  VAL   A N    1 ? 
ATOM   2450 C CA   . VAL   A 1 157 ? 3.938   -62.291 125.25  1   85.374  ? 851  VAL   A CA   1 ? 
ATOM   2451 C C    . VAL   A 1 157 ? 3.805   -62.431 123.734 1   88.997  ? 851  VAL   A C    1 ? 
ATOM   2452 O O    . VAL   A 1 157 ? 3.752   -63.547 123.222 1   86.77   ? 851  VAL   A O    1 ? 
ATOM   2453 C CB   . VAL   A 1 157 ? 5.367   -61.867 125.647 1   86.612  ? 851  VAL   A CB   1 ? 
ATOM   2454 C CG1  . VAL   A 1 157 ? 5.452   -61.416 127.099 1   88.14   ? 851  VAL   A CG1  1 ? 
ATOM   2455 C CG2  . VAL   A 1 157 ? 6.39    -62.963 125.381 1   97.482  ? 851  VAL   A CG2  1 ? 
ATOM   2456 H H    . VAL   A 1 157 ? 4.125   -64.271 125.765 1   85.72   ? 851  VAL   A H    1 c 
ATOM   2457 H HA   . VAL   A 1 157 ? 3.318   -61.604 125.553 1   86.685  ? 851  VAL   A HA   1 c 
ATOM   2458 H HB   . VAL   A 1 157 ? 5.604   -61.096 125.084 1   88.705  ? 851  VAL   A HB   1 c 
ATOM   2459 H HG11 . VAL   A 1 157 ? 5.073   -62.101 127.675 1   87.718  ? 851  VAL   A HG11 1 c 
ATOM   2460 H HG12 . VAL   A 1 157 ? 4.956   -60.589 127.21  1   87.776  ? 851  VAL   A HG12 1 c 
ATOM   2461 H HG13 . VAL   A 1 157 ? 6.382   -61.269 127.34  1   87.76   ? 851  VAL   A HG13 1 c 
ATOM   2462 H HG21 . VAL   A 1 157 ? 7.284   -62.582 125.394 1   94.107  ? 851  VAL   A HG21 1 c 
ATOM   2463 H HG22 . VAL   A 1 157 ? 6.223   -63.363 124.51  1   94.089  ? 851  VAL   A HG22 1 c 
ATOM   2464 H HG23 . VAL   A 1 157 ? 6.321   -63.646 126.069 1   94.035  ? 851  VAL   A HG23 1 c 
ATOM   2465 N N    . LYS   A 1 158 ? 3.784   -61.294 123.019 1   91.019  ? 852  LYS   A N    1 ? 
ATOM   2466 C CA   . LYS   A 1 158 ? 3.679   -61.302 121.568 1   79.339  ? 852  LYS   A CA   1 ? 
ATOM   2467 C C    . LYS   A 1 158 ? 4.487   -60.17  120.942 1   85.712  ? 852  LYS   A C    1 ? 
ATOM   2468 O O    . LYS   A 1 158 ? 4.512   -59.063 121.475 1   87.57   ? 852  LYS   A O    1 ? 
ATOM   2469 C CB   . LYS   A 1 158 ? 2.218   -61.139 121.16  1   88.328  ? 852  LYS   A CB   1 ? 
ATOM   2470 C CG   . LYS   A 1 158 ? 1.408   -62.409 121.192 1   88.616  ? 852  LYS   A CG   1 ? 
ATOM   2471 C CD   . LYS   A 1 158 ? -0.062  -62.157 120.9   1   93.932  ? 852  LYS   A CD   1 ? 
ATOM   2472 C CE   . LYS   A 1 158 ? -0.962  -63.303 121.232 1   103.139 ? 852  LYS   A CE   1 ? 
ATOM   2473 N NZ   . LYS   A 1 158 ? -1.649  -63.774 120.027 1   112.395 ? 852  LYS   A NZ   1 ? 
ATOM   2474 H H    . LYS   A 1 158 ? 3.836   -60.491 123.452 1   87.739  ? 852  LYS   A H    1 c 
ATOM   2475 H HA   . LYS   A 1 158 ? 4.021   -62.167 121.23  1   84.513  ? 852  LYS   A HA   1 c 
ATOM   2476 H HB2  . LYS   A 1 158 ? 1.799   -60.488 121.757 1   86.638  ? 852  LYS   A HB2  1 c 
ATOM   2477 H HB3  . LYS   A 1 158 ? 2.182   -60.774 120.25  1   86.335  ? 852  LYS   A HB3  1 c 
ATOM   2478 H HG2  . LYS   A 1 158 ? 1.767   -63.032 120.525 1   89.857  ? 852  LYS   A HG2  1 c 
ATOM   2479 H HG3  . LYS   A 1 158 ? 1.496   -62.821 122.078 1   89.812  ? 852  LYS   A HG3  1 c 
ATOM   2480 H HD2  . LYS   A 1 158 ? -0.355  -61.369 121.404 1   94.884  ? 852  LYS   A HD2  1 c 
ATOM   2481 H HD3  . LYS   A 1 158 ? -0.157  -61.944 119.946 1   95.104  ? 852  LYS   A HD3  1 c 
ATOM   2482 H HE2  . LYS   A 1 158 ? -0.452  -64.034 121.623 1   102.802 ? 852  LYS   A HE2  1 c 
ATOM   2483 H HE3  . LYS   A 1 158 ? -1.627  -63.015 121.883 1   102.977 ? 852  LYS   A HE3  1 c 
ATOM   2484 H HZ1  . LYS   A 1 158 ? -1.042  -64.038 119.409 1   109.231 ? 852  LYS   A HZ1  1 c 
ATOM   2485 H HZ2  . LYS   A 1 158 ? -2.158  -63.109 119.682 1   109.302 ? 852  LYS   A HZ2  1 c 
ATOM   2486 H HZ3  . LYS   A 1 158 ? -2.182  -64.477 120.236 1   109.385 ? 852  LYS   A HZ3  1 c 
ATOM   2487 N N    . ILE   A 1 159 ? 5.109   -60.451 119.78  1   102.729 ? 853  ILE   A N    1 ? 
ATOM   2488 C CA   . ILE   A 1 159 ? 5.875   -59.455 119.034 1   104.517 ? 853  ILE   A CA   1 ? 
ATOM   2489 C C    . ILE   A 1 159 ? 4.913   -58.513 118.306 1   97.624  ? 853  ILE   A C    1 ? 
ATOM   2490 O O    . ILE   A 1 159 ? 3.826   -58.922 117.906 1   98.965  ? 853  ILE   A O    1 ? 
ATOM   2491 C CB   . ILE   A 1 159 ? 6.873   -60.118 118.063 1   105.171 ? 853  ILE   A CB   1 ? 
ATOM   2492 C CG1  . ILE   A 1 159 ? 7.929   -60.914 118.792 1   107.58  ? 853  ILE   A CG1  1 ? 
ATOM   2493 C CG2  . ILE   A 1 159 ? 7.535   -59.093 117.152 1   111.611 ? 853  ILE   A CG2  1 ? 
ATOM   2494 C CD1  . ILE   A 1 159 ? 8.138   -62.293 118.202 1   119.459 ? 853  ILE   A CD1  1 ? 
ATOM   2495 H H    . ILE   A 1 159 ? 5.05    -61.297 119.441 1   98.485  ? 853  ILE   A H    1 c 
ATOM   2496 H HA   . ILE   A 1 159 ? 6.389   -58.929 119.676 1   102.742 ? 853  ILE   A HA   1 c 
ATOM   2497 H HB   . ILE   A 1 159 ? 6.37    -60.738 117.499 1   106.802 ? 853  ILE   A HB   1 c 
ATOM   2498 H HG12 . ILE   A 1 159 ? 8.776   -60.424 118.761 1   109.616 ? 853  ILE   A HG12 1 c 
ATOM   2499 H HG13 . ILE   A 1 159 ? 7.669   -61.006 119.731 1   109.55  ? 853  ILE   A HG13 1 c 
ATOM   2500 H HG21 . ILE   A 1 159 ? 8.231   -59.525 116.629 1   109.756 ? 853  ILE   A HG21 1 c 
ATOM   2501 H HG22 . ILE   A 1 159 ? 7.93    -58.386 117.69  1   109.67  ? 853  ILE   A HG22 1 c 
ATOM   2502 H HG23 . ILE   A 1 159 ? 6.874   -58.71  116.554 1   110.114 ? 853  ILE   A HG23 1 c 
ATOM   2503 H HD11 . ILE   A 1 159 ? 7.296   -62.783 118.229 1   115.28  ? 853  ILE   A HD11 1 c 
ATOM   2504 H HD12 . ILE   A 1 159 ? 8.809   -62.772 118.723 1   115.565 ? 853  ILE   A HD12 1 c 
ATOM   2505 H HD13 . ILE   A 1 159 ? 8.439   -62.216 117.277 1   115.667 ? 853  ILE   A HD13 1 c 
ATOM   2506 N N    . THR   A 1 160 ? 5.34    -57.252 118.142 1   94.844  ? 854  THR   A N    1 ? 
ATOM   2507 C CA   . THR   A 1 160 ? 4.51    -56.181 117.601 1   92.39   ? 854  THR   A CA   1 ? 
ATOM   2508 C C    . THR   A 1 160 ? 5.39    -55.179 116.862 1   96.313  ? 854  THR   A C    1 ? 
ATOM   2509 O O    . THR   A 1 160 ? 6.59    -55.374 116.764 1   102.941 ? 854  THR   A O    1 ? 
ATOM   2510 C CB   . THR   A 1 160 ? 3.728   -55.496 118.725 1   109.26  ? 854  THR   A CB   1 ? 
ATOM   2511 O OG1  . THR   A 1 160 ? 2.666   -54.786 118.085 1   123.62  ? 854  THR   A OG1  1 ? 
ATOM   2512 C CG2  . THR   A 1 160 ? 4.567   -54.568 119.592 1   123.334 ? 854  THR   A CG2  1 ? 
ATOM   2513 H H    . THR   A 1 160 ? 6.195   -57.047 118.392 1   95.261  ? 854  THR   A H    1 c 
ATOM   2514 H HA   . THR   A 1 160 ? 3.871   -56.57  116.965 1   96.649  ? 854  THR   A HA   1 c 
ATOM   2515 H HB   . THR   A 1 160 ? 3.339   -56.19  119.309 1   110.986 ? 854  THR   A HB   1 c 
ATOM   2516 H HG1  . THR   A 1 160 ? 3.011   -54.137 117.679 0   124.3   ? 854  THR   A HG1  1 c 
ATOM   2517 H HG21 . THR   A 1 160 ? 3.98    -53.955 120.069 1   118.881 ? 854  THR   A HG21 1 c 
ATOM   2518 H HG22 . THR   A 1 160 ? 5.181   -54.058 119.035 1   118.778 ? 854  THR   A HG22 1 c 
ATOM   2519 H HG23 . THR   A 1 160 ? 5.068   -55.095 120.233 1   118.636 ? 854  THR   A HG23 1 c 
ATOM   2520 N N    . ASP   A 1 161 ? 4.775   -54.102 116.347 1   120.726 ? 855  ASP   A N    1 ? 
ATOM   2521 C CA   . ASP   A 1 161 ? 5.439   -53.018 115.636 1   124.834 ? 855  ASP   A CA   1 ? 
ATOM   2522 C C    . ASP   A 1 161 ? 6.108   -53.503 114.356 1   124.075 ? 855  ASP   A C    1 ? 
ATOM   2523 O O    . ASP   A 1 161 ? 7.281   -53.254 114.127 1   116.478 ? 855  ASP   A O    1 ? 
ATOM   2524 C CB   . ASP   A 1 161 ? 6.412   -52.258 116.507 1   129.031 ? 855  ASP   A CB   1 ? 
ATOM   2525 C CG   . ASP   A 1 161 ? 6.08    -50.783 116.603 1   138.251 ? 855  ASP   A CG   1 ? 
ATOM   2526 O OD1  . ASP   A 1 161 ? 4.993   -50.473 117.12  1   141.243 ? 855  ASP   A OD1  1 ? 
ATOM   2527 O OD2  . ASP   A 1 161 ? 6.888   -49.981 116.116 1   147.711 ? 855  ASP   A OD2  1 ? 
ATOM   2528 H H    . ASP   A 1 161 ? 3.868   -54.047 116.445 1   115.031 ? 855  ASP   A H    1 c 
ATOM   2529 H HA   . ASP   A 1 161 ? 4.743   -52.373 115.374 1   124.829 ? 855  ASP   A HA   1 c 
ATOM   2530 H HB2  . ASP   A 1 161 ? 6.382   -52.63  117.413 1   129.537 ? 855  ASP   A HB2  1 c 
ATOM   2531 H HB3  . ASP   A 1 161 ? 7.329   -52.35  116.176 1   129.981 ? 855  ASP   A HB3  1 c 
ATOM   2532 N N    . PHE   A 1 162 ? 5.301   -54.089 113.478 1   154.072 ? 856  PHE   A N    1 ? 
ATOM   2533 C CA   . PHE   A 1 162 ? 5.738   -54.519 112.161 1   165.842 ? 856  PHE   A CA   1 ? 
ATOM   2534 C C    . PHE   A 1 162 ? 5.56    -53.416 111.115 1   183.473 ? 856  PHE   A C    1 ? 
ATOM   2535 O O    . PHE   A 1 162 ? 5.821   -53.644 109.937 1   200.798 ? 856  PHE   A O    1 ? 
ATOM   2536 C CB   . PHE   A 1 162 ? 4.889   -55.696 111.677 1   175.785 ? 856  PHE   A CB   1 ? 
ATOM   2537 C CG   . PHE   A 1 162 ? 4.681   -56.764 112.728 1   165.765 ? 856  PHE   A CG   1 ? 
ATOM   2538 C CD1  . PHE   A 1 162 ? 5.753   -57.532 113.146 1   158.215 ? 856  PHE   A CD1  1 ? 
ATOM   2539 C CD2  . PHE   A 1 162 ? 3.425   -56.978 113.287 1   150.936 ? 856  PHE   A CD2  1 ? 
ATOM   2540 C CE1  . PHE   A 1 162 ? 5.568   -58.487 114.117 1   173.949 ? 856  PHE   A CE1  1 ? 
ATOM   2541 C CE2  . PHE   A 1 162 ? 3.251   -57.931 114.264 1   148.943 ? 856  PHE   A CE2  1 ? 
ATOM   2542 C CZ   . PHE   A 1 162 ? 4.321   -58.688 114.671 1   179.278 ? 856  PHE   A CZ   1 ? 
ATOM   2543 H H    . PHE   A 1 162 ? 4.425   -54.217 113.707 1   148.632 ? 856  PHE   A H    1 c 
ATOM   2544 H HA   . PHE   A 1 162 ? 6.692   -54.792 112.2   1   167.475 ? 856  PHE   A HA   1 c 
ATOM   2545 H HB2  . PHE   A 1 162 ? 4.013   -55.355 111.391 1   170.986 ? 856  PHE   A HB2  1 c 
ATOM   2546 H HB3  . PHE   A 1 162 ? 5.328   -56.099 110.896 1   171.107 ? 856  PHE   A HB3  1 c 
ATOM   2547 H HD1  . PHE   A 1 162 ? 6.609   -57.392 112.773 1   163.555 ? 856  PHE   A HD1  1 c 
ATOM   2548 H HD2  . PHE   A 1 162 ? 2.696   -56.446 113.013 1   153.905 ? 856  PHE   A HD2  1 c 
ATOM   2549 H HE1  . PHE   A 1 162 ? 6.298   -59.014 114.399 1   169.601 ? 856  PHE   A HE1  1 c 
ATOM   2550 H HE2  . PHE   A 1 162 ? 2.397   -58.073 114.641 1   156.277 ? 856  PHE   A HE2  1 c 
ATOM   2551 H HZ   . PHE   A 1 162 ? 4.204   -59.352 115.33  1   168.92  ? 856  PHE   A HZ   1 c 
ATOM   2552 N N    . GLY   A 1 163 ? 5.108   -52.226 111.536 1   160.402 ? 857  GLY   A N    1 ? 
ATOM   2553 C CA   . GLY   A 1 163 ? 4.911   -51.114 110.624 1   146.736 ? 857  GLY   A CA   1 ? 
ATOM   2554 C C    . GLY   A 1 163 ? 6.131   -50.935 109.721 1   156.467 ? 857  GLY   A C    1 ? 
ATOM   2555 O O    . GLY   A 1 163 ? 5.961   -50.752 108.513 1   177.783 ? 857  GLY   A O    1 ? 
ATOM   2556 H H    . GLY   A 1 163 ? 4.91    -52.104 112.419 1   161.996 ? 857  GLY   A H    1 c 
ATOM   2557 H HA2  . GLY   A 1 163 ? 4.111   -51.284 110.072 1   152.033 ? 857  GLY   A HA2  1 c 
ATOM   2558 H HA3  . GLY   A 1 163 ? 4.757   -50.29  111.143 1   152.032 ? 857  GLY   A HA3  1 c 
ATOM   2559 N N    . LEU   A 1 164 ? 7.337   -51.016 110.323 1   151.929 ? 858  LEU   A N    1 ? 
ATOM   2560 C CA   . LEU   A 1 164 ? 8.62    -50.906 109.629 1   153.534 ? 858  LEU   A CA   1 ? 
ATOM   2561 C C    . LEU   A 1 164 ? 9.034   -52.239 108.993 1   160.992 ? 858  LEU   A C    1 ? 
ATOM   2562 O O    . LEU   A 1 164 ? 10.055  -52.284 108.316 1   162.147 ? 858  LEU   A O    1 ? 
ATOM   2563 C CB   . LEU   A 1 164 ? 9.726   -50.402 110.567 1   121.554 ? 858  LEU   A CB   1 ? 
ATOM   2564 H H    . LEU   A 1 164 ? 7.353   -51.145 111.228 1   153.27  ? 858  LEU   A H    1 c 
ATOM   2565 H HA   . LEU   A 1 164 ? 8.508   -50.247 108.897 1   148.268 ? 858  LEU   A HA   1 c 
ATOM   2566 H HB2  . LEU   A 1 164 ? 10.552  -50.568 110.075 0   128.26  ? 858  LEU   A HB2  1 c 
ATOM   2567 H HB3  . LEU   A 1 164 ? 9.235   -49.918 111.236 0   128.26  ? 858  LEU   A HB3  1 c 
ATOM   2568 N N    . ALA   A 1 165 ? 8.242   -53.308 109.18  1   166.037 ? 859  ALA   A N    1 ? 
ATOM   2569 C CA   . ALA   A 1 165 ? 8.643   -54.654 108.782 1   160.204 ? 859  ALA   A CA   1 ? 
ATOM   2570 C C    . ALA   A 1 165 ? 8.721   -54.775 107.257 1   174.94  ? 859  ALA   A C    1 ? 
ATOM   2571 O O    . ALA   A 1 165 ? 7.9     -54.185 106.557 1   178.133 ? 859  ALA   A O    1 ? 
ATOM   2572 C CB   . ALA   A 1 165 ? 7.7     -55.686 109.368 1   139.504 ? 859  ALA   A CB   1 ? 
ATOM   2573 H H    . ALA   A 1 165 ? 7.421   -53.195 109.559 1   163.252 ? 859  ALA   A H    1 c 
ATOM   2574 H HA   . ALA   A 1 165 ? 9.555   -54.814 109.147 1   159.706 ? 859  ALA   A HA   1 c 
ATOM   2575 H HB1  . ALA   A 1 165 ? 7.598   -55.533 110.321 1   145.922 ? 859  ALA   A HB1  1 c 
ATOM   2576 H HB2  . ALA   A 1 165 ? 6.832   -55.621 108.935 1   145.763 ? 859  ALA   A HB2  1 c 
ATOM   2577 H HB3  . ALA   A 1 165 ? 8.062   -56.577 109.224 1   145.529 ? 859  ALA   A HB3  1 c 
ATOM   2578 N N    . LYS   A 1 166 ? 9.709   -55.55  106.762 1   173.426 ? 860  LYS   A N    1 ? 
ATOM   2579 C CA   . LYS   A 1 166 ? 9.975   -55.731 105.335 1   162.626 ? 860  LYS   A CA   1 ? 
ATOM   2580 C C    . LYS   A 1 166 ? 10.255  -57.206 105     1   167.011 ? 860  LYS   A C    1 ? 
ATOM   2581 O O    . LYS   A 1 166 ? 10.728  -57.949 105.86  1   185.302 ? 860  LYS   A O    1 ? 
ATOM   2582 C CB   . LYS   A 1 166 ? 11.179  -54.864 104.948 1   134.257 ? 860  LYS   A CB   1 ? 
ATOM   2583 H H    . LYS   A 1 166 ? 10.246  -55.992 107.355 1   170.849 ? 860  LYS   A H    1 c 
ATOM   2584 H HA   . LYS   A 1 166 ? 9.18    -55.433 104.823 1   160.068 ? 860  LYS   A HA   1 c 
ATOM   2585 H HB2  . LYS   A 1 166 ? 11.947  -55.275 105.1   0   140.6   ? 860  LYS   A HB2  1 c 
ATOM   2586 H HB3  . LYS   A 1 166 ? 10.731  -54.009 104.487 0   140.6   ? 860  LYS   A HB3  1 c 
ATOM   2587 N N    . LEU   A 1 167 ? 9.956   -57.616 103.749 1   181.498 ? 861  LEU   A N    1 ? 
ATOM   2588 C CA   . LEU   A 1 167 ? 10.297  -58.934 103.209 1   185.112 ? 861  LEU   A CA   1 ? 
ATOM   2589 C C    . LEU   A 1 167 ? 11.817  -59.032 103.059 1   190.726 ? 861  LEU   A C    1 ? 
ATOM   2590 O O    . LEU   A 1 167 ? 12.436  -58.027 102.731 1   190.021 ? 861  LEU   A O    1 ? 
ATOM   2591 C CB   . LEU   A 1 167 ? 9.63    -59.178 101.846 1   170.394 ? 861  LEU   A CB   1 ? 
ATOM   2592 C CG   . LEU   A 1 167 ? 8.286   -59.92  101.802 1   154.759 ? 861  LEU   A CG   1 ? 
ATOM   2593 C CD1  . LEU   A 1 167 ? 8.129   -60.682 100.485 1   144.558 ? 861  LEU   A CD1  1 ? 
ATOM   2594 C CD2  . LEU   A 1 167 ? 8.096   -60.872 102.968 1   155.655 ? 861  LEU   A CD2  1 ? 
ATOM   2595 H H    . LEU   A 1 167 ? 9.513   -57.032 103.203 1   178.317 ? 861  LEU   A H    1 c 
ATOM   2596 H HA   . LEU   A 1 167 ? 10.001  -59.62  103.854 1   182.15  ? 861  LEU   A HA   1 c 
ATOM   2597 H HB2  . LEU   A 1 167 ? 9.509   -58.305 101.408 1   169.961 ? 861  LEU   A HB2  1 c 
ATOM   2598 H HB3  . LEU   A 1 167 ? 10.269  -59.675 101.284 1   169.7   ? 861  LEU   A HB3  1 c 
ATOM   2599 H HG   . LEU   A 1 167 ? 7.563   -59.243 101.846 1   155.711 ? 861  LEU   A HG   1 c 
ATOM   2600 H HD11 . LEU   A 1 167 ? 8.208   -60.063 99.74   1   147.525 ? 861  LEU   A HD11 1 c 
ATOM   2601 H HD12 . LEU   A 1 167 ? 7.256   -61.109 100.458 1   147.565 ? 861  LEU   A HD12 1 c 
ATOM   2602 H HD13 . LEU   A 1 167 ? 8.822   -61.36  100.416 1   147.633 ? 861  LEU   A HD13 1 c 
ATOM   2603 H HD21 . LEU   A 1 167 ? 7.934   -60.366 103.781 1   155.534 ? 861  LEU   A HD21 1 c 
ATOM   2604 H HD22 . LEU   A 1 167 ? 8.895   -61.416 103.077 1   155.599 ? 861  LEU   A HD22 1 c 
ATOM   2605 H HD23 . LEU   A 1 167 ? 7.334   -61.45  102.792 1   155.267 ? 861  LEU   A HD23 1 c 
ATOM   2606 N N    . LEU   A 1 168 ? 12.417  -60.222 103.264 1   193.234 ? 862  LEU   A N    1 ? 
ATOM   2607 C CA   . LEU   A 1 168 ? 13.851  -60.413 103.027 1   189.396 ? 862  LEU   A CA   1 ? 
ATOM   2608 C C    . LEU   A 1 168 ? 14.138  -60.326 101.519 1   197.487 ? 862  LEU   A C    1 ? 
ATOM   2609 O O    . LEU   A 1 168 ? 13.467  -61.011 100.758 1   208.509 ? 862  LEU   A O    1 ? 
ATOM   2610 C CB   . LEU   A 1 168 ? 14.315  -61.755 103.612 1   190.503 ? 862  LEU   A CB   1 ? 
ATOM   2611 C CG   . LEU   A 1 168 ? 15.828  -62.032 103.606 1   188.398 ? 862  LEU   A CG   1 ? 
ATOM   2612 C CD1  . LEU   A 1 168 ? 16.545  -61.306 104.733 1   172.097 ? 862  LEU   A CD1  1 ? 
ATOM   2613 C CD2  . LEU   A 1 168 ? 16.149  -63.52  103.662 1   179.504 ? 862  LEU   A CD2  1 ? 
ATOM   2614 H H    . LEU   A 1 168 ? 11.92   -60.931 103.558 1   191.641 ? 862  LEU   A H    1 c 
ATOM   2615 H HA   . LEU   A 1 168 ? 14.338  -59.68  103.483 1   191.875 ? 862  LEU   A HA   1 c 
ATOM   2616 H HB2  . LEU   A 1 168 ? 13.995  -61.809 104.542 1   189.761 ? 862  LEU   A HB2  1 c 
ATOM   2617 H HB3  . LEU   A 1 168 ? 13.868  -62.476 103.111 1   189.713 ? 862  LEU   A HB3  1 c 
ATOM   2618 H HG   . LEU   A 1 168 ? 16.195  -61.685 102.753 1   183.993 ? 862  LEU   A HG   1 c 
ATOM   2619 H HD11 . LEU   A 1 168 ? 16.401  -60.349 104.647 1   176.756 ? 862  LEU   A HD11 1 c 
ATOM   2620 H HD12 . LEU   A 1 168 ? 17.497  -61.495 104.687 1   176.756 ? 862  LEU   A HD12 1 c 
ATOM   2621 H HD13 . LEU   A 1 168 ? 16.197  -61.609 105.588 1   176.756 ? 862  LEU   A HD13 1 c 
ATOM   2622 H HD21 . LEU   A 1 168 ? 15.761  -63.966 102.89  1   182.079 ? 862  LEU   A HD21 1 c 
ATOM   2623 H HD22 . LEU   A 1 168 ? 15.778  -63.903 104.475 1   182.079 ? 862  LEU   A HD22 1 c 
ATOM   2624 H HD23 . LEU   A 1 168 ? 17.113  -63.646 103.657 1   182.079 ? 862  LEU   A HD23 1 c 
ATOM   2625 N N    . GLY   A 1 169 ? 15.056  -59.425 101.081 1   210.623 ? 863  GLY   A N    1 ? 
ATOM   2626 C CA   . GLY   A 1 169 ? 15.743  -59.505 99.784  1   206.392 ? 863  GLY   A CA   1 ? 
ATOM   2627 C C    . GLY   A 1 169 ? 15.49   -58.357 98.787  1   215.103 ? 863  GLY   A C    1 ? 
ATOM   2628 O O    . GLY   A 1 169 ? 15.429  -58.628 97.582  1   222.291 ? 863  GLY   A O    1 ? 
ATOM   2629 H H    . GLY   A 1 169 ? 15.26   -58.722 101.628 1   206.341 ? 863  GLY   A H    1 c 
ATOM   2630 H HA2  . GLY   A 1 169 ? 16.712  -59.555 99.958  1   209.297 ? 863  GLY   A HA2  1 c 
ATOM   2631 H HA3  . GLY   A 1 169 ? 15.486  -60.353 99.352  1   209.237 ? 863  GLY   A HA3  1 c 
ATOM   2632 N N    . ALA   A 1 170 ? 15.471  -57.092 99.267  1   201.471 ? 864  ALA   A N    1 ? 
ATOM   2633 C CA   . ALA   A 1 170 ? 14.958  -55.932 98.541  1   165.639 ? 864  ALA   A CA   1 ? 
ATOM   2634 C C    . ALA   A 1 170 ? 16.092  -54.947 98.223  1   162.655 ? 864  ALA   A C    1 ? 
ATOM   2635 O O    . ALA   A 1 170 ? 16.065  -53.836 98.783  1   169.916 ? 864  ALA   A O    1 ? 
ATOM   2636 C CB   . ALA   A 1 170 ? 13.849  -55.263 99.353  1   126.75  ? 864  ALA   A CB   1 ? 
ATOM   2637 H H    . ALA   A 1 170 ? 15.806  -56.953 100.106 1   195.795 ? 864  ALA   A H    1 c 
ATOM   2638 H HA   . ALA   A 1 170 ? 14.575  -56.25  97.677  1   163.803 ? 864  ALA   A HA   1 c 
ATOM   2639 H HB1  . ALA   A 1 170 ? 13.133  -55.901 99.514  1   137.192 ? 864  ALA   A HB1  1 c 
ATOM   2640 H HB2  . ALA   A 1 170 ? 14.204  -54.96  100.206 1   137.314 ? 864  ALA   A HB2  1 c 
ATOM   2641 H HB3  . ALA   A 1 170 ? 13.495  -54.503 98.862  1   137.309 ? 864  ALA   A HB3  1 c 
ATOM   2642 N N    . VAL   A 1 182 ? 16.006  -43.433 115.093 1   153.441 ? 876  VAL   A N    1 ? 
ATOM   2643 C CA   . VAL   A 1 182 ? 16.231  -44.88  114.779 1   164.087 ? 876  VAL   A CA   1 ? 
ATOM   2644 C C    . VAL   A 1 182 ? 16.81   -45.585 116.006 1   168.111 ? 876  VAL   A C    1 ? 
ATOM   2645 O O    . VAL   A 1 182 ? 17.483  -44.972 116.836 1   170.511 ? 876  VAL   A O    1 ? 
ATOM   2646 C CB   . VAL   A 1 182 ? 17.136  -45.107 113.551 1   147.166 ? 876  VAL   A CB   1 ? 
ATOM   2647 C CG1  . VAL   A 1 182 ? 16.451  -44.683 112.255 1   127.284 ? 876  VAL   A CG1  1 ? 
ATOM   2648 C CG2  . VAL   A 1 182 ? 18.499  -44.447 113.731 1   146.935 ? 876  VAL   A CG2  1 ? 
ATOM   2649 H H    . VAL   A 1 182 ? 15.722  -42.991 114.36  1   156.279 ? 876  VAL   A H    1 c 
ATOM   2650 H HA   . VAL   A 1 182 ? 15.36   -45.275 114.585 1   159.314 ? 876  VAL   A HA   1 c 
ATOM   2651 H HB   . VAL   A 1 182 ? 17.295  -46.076 113.487 1   146.173 ? 876  VAL   A HB   1 c 
ATOM   2652 H HG11 . VAL   A 1 182 ? 16.278  -43.727 112.276 1   132.998 ? 876  VAL   A HG11 1 c 
ATOM   2653 H HG12 . VAL   A 1 182 ? 15.611  -45.162 112.16  1   132.876 ? 876  VAL   A HG12 1 c 
ATOM   2654 H HG13 . VAL   A 1 182 ? 17.029  -44.89  111.501 1   132.878 ? 876  VAL   A HG13 1 c 
ATOM   2655 H HG21 . VAL   A 1 182 ? 19.056  -44.637 112.957 1   147.052 ? 876  VAL   A HG21 1 c 
ATOM   2656 H HG22 . VAL   A 1 182 ? 18.929  -44.797 114.529 1   147.132 ? 876  VAL   A HG22 1 c 
ATOM   2657 H HG23 . VAL   A 1 182 ? 18.388  -43.486 113.819 1   147.129 ? 876  VAL   A HG23 1 c 
ATOM   2658 N N    . PRO   A 1 183 ? 16.573  -46.909 116.143 1   153.008 ? 877  PRO   A N    1 ? 
ATOM   2659 C CA   . PRO   A 1 183 ? 17.04   -47.652 117.299 1   149.552 ? 877  PRO   A CA   1 ? 
ATOM   2660 C C    . PRO   A 1 183 ? 18.468  -48.12  117.078 1   136.082 ? 877  PRO   A C    1 ? 
ATOM   2661 O O    . PRO   A 1 183 ? 18.705  -49.285 116.805 1   140.482 ? 877  PRO   A O    1 ? 
ATOM   2662 C CB   . PRO   A 1 183 ? 16.052  -48.818 117.372 1   161.699 ? 877  PRO   A CB   1 ? 
ATOM   2663 C CG   . PRO   A 1 183 ? 15.794  -49.093 115.889 1   153.711 ? 877  PRO   A CG   1 ? 
ATOM   2664 C CD   . PRO   A 1 183 ? 15.875  -47.774 115.174 1   143.244 ? 877  PRO   A CD   1 ? 
ATOM   2665 H HA   . PRO   A 1 183 ? 16.983  -47.098 118.106 1   149.936 ? 877  PRO   A HA   1 c 
ATOM   2666 H HB2  . PRO   A 1 183 ? 16.447  -49.593 117.816 1   156.803 ? 877  PRO   A HB2  1 c 
ATOM   2667 H HB3  . PRO   A 1 183 ? 15.231  -48.557 117.833 1   156.695 ? 877  PRO   A HB3  1 c 
ATOM   2668 H HG2  . PRO   A 1 183 ? 16.463  -49.712 115.534 1   152.842 ? 877  PRO   A HG2  1 c 
ATOM   2669 H HG3  . PRO   A 1 183 ? 14.911  -49.489 115.764 1   152.705 ? 877  PRO   A HG3  1 c 
ATOM   2670 H HD2  . PRO   A 1 183 ? 16.386  -47.851 114.346 1   147.801 ? 877  PRO   A HD2  1 c 
ATOM   2671 H HD3  . PRO   A 1 183 ? 14.985  -47.425 114.974 1   147.934 ? 877  PRO   A HD3  1 c 
ATOM   2672 N N    . ILE   A 1 184 ? 19.406  -47.183 117.102 1   127.983 ? 878  ILE   A N    1 ? 
ATOM   2673 C CA   . ILE   A 1 184 ? 20.783  -47.478 116.734 1   128.585 ? 878  ILE   A CA   1 ? 
ATOM   2674 C C    . ILE   A 1 184 ? 21.375  -48.541 117.665 1   121.488 ? 878  ILE   A C    1 ? 
ATOM   2675 O O    . ILE   A 1 184 ? 22.141  -49.405 117.23  1   97.109  ? 878  ILE   A O    1 ? 
ATOM   2676 C CB   . ILE   A 1 184 ? 21.619  -46.183 116.731 1   138.617 ? 878  ILE   A CB   1 ? 
ATOM   2677 C CG1  . ILE   A 1 184 ? 23.065  -46.461 116.36  1   140.927 ? 878  ILE   A CG1  1 ? 
ATOM   2678 C CG2  . ILE   A 1 184 ? 21.511  -45.447 118.069 1   149.539 ? 878  ILE   A CG2  1 ? 
ATOM   2679 C CD1  . ILE   A 1 184 ? 23.252  -46.887 114.917 1   142.262 ? 878  ILE   A CD1  1 ? 
ATOM   2680 H H    . ILE   A 1 184 ? 19.18   -46.329 117.337 1   130.636 ? 878  ILE   A H    1 c 
ATOM   2681 H HA   . ILE   A 1 184 ? 20.781  -47.836 115.828 1   129.048 ? 878  ILE   A HA   1 c 
ATOM   2682 H HB   . ILE   A 1 184 ? 21.248  -45.597 116.041 1   139.079 ? 878  ILE   A HB   1 c 
ATOM   2683 H HG12 . ILE   A 1 184 ? 23.591  -45.651 116.518 1   140.657 ? 878  ILE   A HG12 1 c 
ATOM   2684 H HG13 . ILE   A 1 184 ? 23.417  -47.162 116.945 1   140.299 ? 878  ILE   A HG13 1 c 
ATOM   2685 H HG21 . ILE   A 1 184 ? 21.547  -44.487 117.91  1   146.09  ? 878  ILE   A HG21 1 c 
ATOM   2686 H HG22 . ILE   A 1 184 ? 22.252  -45.712 118.649 1   146.082 ? 878  ILE   A HG22 1 c 
ATOM   2687 H HG23 . ILE   A 1 184 ? 20.666  -45.667 118.502 1   145.68  ? 878  ILE   A HG23 1 c 
ATOM   2688 H HD11 . ILE   A 1 184 ? 22.824  -47.751 114.775 1   141.557 ? 878  ILE   A HD11 1 c 
ATOM   2689 H HD12 . ILE   A 1 184 ? 24.204  -46.958 114.719 1   141.606 ? 878  ILE   A HD12 1 c 
ATOM   2690 H HD13 . ILE   A 1 184 ? 22.847  -46.224 114.326 1   141.757 ? 878  ILE   A HD13 1 c 
ATOM   2691 N N    . LYS   A 1 185 ? 21.037  -48.454 118.958 1   125.298 ? 879  LYS   A N    1 ? 
ATOM   2692 C CA   . LYS   A 1 185 ? 21.63   -49.311 119.973 1   118.373 ? 879  LYS   A CA   1 ? 
ATOM   2693 C C    . LYS   A 1 185 ? 21.202  -50.768 119.813 1   121.131 ? 879  LYS   A C    1 ? 
ATOM   2694 O O    . LYS   A 1 185 ? 21.988  -51.664 120.116 1   119.506 ? 879  LYS   A O    1 ? 
ATOM   2695 C CB   . LYS   A 1 185 ? 21.294  -48.782 121.367 1   120.211 ? 879  LYS   A CB   1 ? 
ATOM   2696 C CG   . LYS   A 1 185 ? 22.255  -47.689 121.773 1   129.748 ? 879  LYS   A CG   1 ? 
ATOM   2697 C CD   . LYS   A 1 185 ? 21.764  -46.849 122.937 1   130.576 ? 879  LYS   A CD   1 ? 
ATOM   2698 C CE   . LYS   A 1 185 ? 22.666  -45.691 123.174 1   128.7   ? 879  LYS   A CE   1 ? 
ATOM   2699 N NZ   . LYS   A 1 185 ? 22.051  -44.725 124.085 1   140.192 ? 879  LYS   A NZ   1 ? 
ATOM   2700 H H    . LYS   A 1 185 ? 20.415  -47.837 119.217 1   123.185 ? 879  LYS   A H    1 c 
ATOM   2701 H HA   . LYS   A 1 185 ? 22.614  -49.27  119.865 1   120.463 ? 879  LYS   A HA   1 c 
ATOM   2702 H HB2  . LYS   A 1 185 ? 20.38   -48.427 121.376 1   121.912 ? 879  LYS   A HB2  1 c 
ATOM   2703 H HB3  . LYS   A 1 185 ? 21.347  -49.514 122.019 1   121.911 ? 879  LYS   A HB3  1 c 
ATOM   2704 H HG2  . LYS   A 1 185 ? 23.115  -48.093 122.006 1   127.332 ? 879  LYS   A HG2  1 c 
ATOM   2705 H HG3  . LYS   A 1 185 ? 22.403  -47.103 120.999 1   127.578 ? 879  LYS   A HG3  1 c 
ATOM   2706 H HD2  . LYS   A 1 185 ? 20.859  -46.52  122.743 1   129.908 ? 879  LYS   A HD2  1 c 
ATOM   2707 H HD3  . LYS   A 1 185 ? 21.726  -47.402 123.745 1   129.788 ? 879  LYS   A HD3  1 c 
ATOM   2708 H HE2  . LYS   A 1 185 ? 23.508  -45.996 123.555 1   131.508 ? 879  LYS   A HE2  1 c 
ATOM   2709 H HE3  . LYS   A 1 185 ? 22.859  -45.247 122.328 1   131.681 ? 879  LYS   A HE3  1 c 
ATOM   2710 H HZ1  . LYS   A 1 185 ? 21.853  -45.129 124.871 1   136.501 ? 879  LYS   A HZ1  1 c 
ATOM   2711 H HZ2  . LYS   A 1 185 ? 21.29   -44.399 123.717 1   136.493 ? 879  LYS   A HZ2  1 c 
ATOM   2712 H HZ3  . LYS   A 1 185 ? 22.625  -44.041 124.238 1   136.528 ? 879  LYS   A HZ3  1 c 
ATOM   2713 N N    . TRP   A 1 186 ? 19.971  -51.001 119.325 1   108.933 ? 880  TRP   A N    1 ? 
ATOM   2714 C CA   . TRP   A 1 186 ? 19.487  -52.346 119.042 1   95.112  ? 880  TRP   A CA   1 ? 
ATOM   2715 C C    . TRP   A 1 186 ? 20.029  -52.903 117.729 1   90.974  ? 880  TRP   A C    1 ? 
ATOM   2716 O O    . TRP   A 1 186 ? 19.948  -54.109 117.515 1   82.163  ? 880  TRP   A O    1 ? 
ATOM   2717 C CB   . TRP   A 1 186 ? 17.962  -52.374 119.013 1   99.067  ? 880  TRP   A CB   1 ? 
ATOM   2718 C CG   . TRP   A 1 186 ? 17.383  -52.285 120.391 1   103.57  ? 880  TRP   A CG   1 ? 
ATOM   2719 C CD1  . TRP   A 1 186 ? 16.827  -53.291 121.127 1   97.411  ? 880  TRP   A CD1  1 ? 
ATOM   2720 C CD2  . TRP   A 1 186 ? 17.361  -51.104 121.209 1   101.528 ? 880  TRP   A CD2  1 ? 
ATOM   2721 N NE1  . TRP   A 1 186 ? 16.423  -52.808 122.339 1   101.579 ? 880  TRP   A NE1  1 ? 
ATOM   2722 C CE2  . TRP   A 1 186 ? 16.738  -51.474 122.418 1   102.676 ? 880  TRP   A CE2  1 ? 
ATOM   2723 C CE3  . TRP   A 1 186 ? 17.781  -49.785 121.03  1   108.85  ? 880  TRP   A CE3  1 ? 
ATOM   2724 C CZ2  . TRP   A 1 186 ? 16.537  -50.56  123.445 1   102.558 ? 880  TRP   A CZ2  1 ? 
ATOM   2725 C CZ3  . TRP   A 1 186 ? 17.614  -48.894 122.062 1   108.766 ? 880  TRP   A CZ3  1 ? 
ATOM   2726 C CH2  . TRP   A 1 186 ? 16.982  -49.273 123.242 1   101.645 ? 880  TRP   A CH2  1 ? 
ATOM   2727 H H    . TRP   A 1 186 ? 19.434  -50.292 119.119 1   108.368 ? 880  TRP   A H    1 c 
ATOM   2728 H HA   . TRP   A 1 186 ? 19.789  -52.942 119.779 1   97.796  ? 880  TRP   A HA   1 c 
ATOM   2729 H HB2  . TRP   A 1 186 ? 17.64   -51.618 118.478 1   99.203  ? 880  TRP   A HB2  1 c 
ATOM   2730 H HB3  . TRP   A 1 186 ? 17.667  -53.211 118.595 1   99.039  ? 880  TRP   A HB3  1 c 
ATOM   2731 H HD1  . TRP   A 1 186 ? 16.706  -54.182 120.839 1   99.779  ? 880  TRP   A HD1  1 c 
ATOM   2732 H HE1  . TRP   A 1 186 ? 16.034  -53.278 122.959 1   100.928 ? 880  TRP   A HE1  1 c 
ATOM   2733 H HE3  . TRP   A 1 186 ? 18.198  -49.518 120.234 1   107.028 ? 880  TRP   A HE3  1 c 
ATOM   2734 H HZ2  . TRP   A 1 186 ? 16.134  -50.817 124.256 1   102.483 ? 880  TRP   A HZ2  1 c 
ATOM   2735 H HZ3  . TRP   A 1 186 ? 17.883  -47.998 121.949 1   106.982 ? 880  TRP   A HZ3  1 c 
ATOM   2736 H HH2  . TRP   A 1 186 ? 16.866  -48.637 123.925 1   103.504 ? 880  TRP   A HH2  1 c 
ATOM   2737 N N    . MET   A 1 187 ? 20.565  -52.034 116.86  1   101.954 ? 881  MET   A N    1 ? 
ATOM   2738 C CA   . MET   A 1 187 ? 20.875  -52.403 115.484 1   104.351 ? 881  MET   A CA   1 ? 
ATOM   2739 C C    . MET   A 1 187 ? 22.206  -53.148 115.377 1   100.323 ? 881  MET   A C    1 ? 
ATOM   2740 O O    . MET   A 1 187 ? 23.137  -52.891 116.136 1   113.752 ? 881  MET   A O    1 ? 
ATOM   2741 C CB   . MET   A 1 187 ? 20.969  -51.163 114.596 1   113.795 ? 881  MET   A CB   1 ? 
ATOM   2742 C CG   . MET   A 1 187 ? 19.753  -50.276 114.61  1   122.031 ? 881  MET   A CG   1 ? 
ATOM   2743 S SD   . MET   A 1 187 ? 19.913  -48.926 113.428 1   126.041 ? 881  MET   A SD   1 ? 
ATOM   2744 C CE   . MET   A 1 187 ? 20.815  -49.722 112.089 1   116.052 ? 881  MET   A CE   1 ? 
ATOM   2745 H H    . MET   A 1 187 ? 20.746  -51.181 117.133 1   100.324 ? 881  MET   A H    1 c 
ATOM   2746 H HA   . MET   A 1 187 ? 20.151  -52.992 115.149 1   104.522 ? 881  MET   A HA   1 c 
ATOM   2747 H HB2  . MET   A 1 187 ? 21.747  -50.637 114.879 1   113.222 ? 881  MET   A HB2  1 c 
ATOM   2748 H HB3  . MET   A 1 187 ? 21.133  -51.464 113.679 1   113.359 ? 881  MET   A HB3  1 c 
ATOM   2749 H HG2  . MET   A 1 187 ? 18.958  -50.802 114.391 1   120.737 ? 881  MET   A HG2  1 c 
ATOM   2750 H HG3  . MET   A 1 187 ? 19.639  -49.907 115.495 1   120.76  ? 881  MET   A HG3  1 c 
ATOM   2751 H HE1  . MET   A 1 187 ? 20.794  -49.148 111.301 1   118.478 ? 881  MET   A HE1  1 c 
ATOM   2752 H HE2  . MET   A 1 187 ? 21.741  -49.865 112.357 1   118.501 ? 881  MET   A HE2  1 c 
ATOM   2753 H HE3  . MET   A 1 187 ? 20.39   -50.572 111.877 1   118.488 ? 881  MET   A HE3  1 c 
ATOM   2754 N N    . ALA   A 1 188 ? 22.286  -54.056 114.396 1   97.96   ? 882  ALA   A N    1 ? 
ATOM   2755 C CA   . ALA   A 1 188 ? 23.516  -54.767 114.07  1   102.757 ? 882  ALA   A CA   1 ? 
ATOM   2756 C C    . ALA   A 1 188 ? 24.476  -53.81  113.377 1   104.784 ? 882  ALA   A C    1 ? 
ATOM   2757 O O    . ALA   A 1 188 ? 24.043  -52.814 112.815 1   130.174 ? 882  ALA   A O    1 ? 
ATOM   2758 C CB   . ALA   A 1 188 ? 23.216  -55.955 113.167 1   107.208 ? 882  ALA   A CB   1 ? 
ATOM   2759 H H    . ALA   A 1 188 ? 21.537  -54.24  113.905 1   99.709  ? 882  ALA   A H    1 c 
ATOM   2760 H HA   . ALA   A 1 188 ? 23.935  -55.085 114.916 1   103.059 ? 882  ALA   A HA   1 c 
ATOM   2761 H HB1  . ALA   A 1 188 ? 22.547  -56.524 113.586 1   105.944 ? 882  ALA   A HB1  1 c 
ATOM   2762 H HB2  . ALA   A 1 188 ? 22.88   -55.64  112.311 1   105.944 ? 882  ALA   A HB2  1 c 
ATOM   2763 H HB3  . ALA   A 1 188 ? 24.029  -56.467 113.026 1   106.159 ? 882  ALA   A HB3  1 c 
ATOM   2764 N N    . LEU   A 1 189 ? 25.766  -54.146 113.38  1   122.868 ? 883  LEU   A N    1 ? 
ATOM   2765 C CA   . LEU   A 1 189 ? 26.778  -53.301 112.756 1   137.74  ? 883  LEU   A CA   1 ? 
ATOM   2766 C C    . LEU   A 1 189 ? 26.535  -53.207 111.248 1   128.405 ? 883  LEU   A C    1 ? 
ATOM   2767 O O    . LEU   A 1 189 ? 26.605  -52.126 110.66  1   124.275 ? 883  LEU   A O    1 ? 
ATOM   2768 C CB   . LEU   A 1 189 ? 28.183  -53.829 113.045 1   131.298 ? 883  LEU   A CB   1 ? 
ATOM   2769 C CG   . LEU   A 1 189 ? 29.324  -52.82  112.879 1   122.471 ? 883  LEU   A CG   1 ? 
ATOM   2770 C CD1  . LEU   A 1 189 ? 29.338  -51.78  114.004 1   125.016 ? 883  LEU   A CD1  1 ? 
ATOM   2771 C CD2  . LEU   A 1 189 ? 30.645  -53.564 112.813 1   133.509 ? 883  LEU   A CD2  1 ? 
ATOM   2772 H H    . LEU   A 1 189 ? 26.026  -54.926 113.78  1   121.187 ? 883  LEU   A H    1 c 
ATOM   2773 H HA   . LEU   A 1 189 ? 26.693  -52.391 113.139 1   131.628 ? 883  LEU   A HA   1 c 
ATOM   2774 H HB2  . LEU   A 1 189 ? 28.2    -54.166 113.971 1   130.547 ? 883  LEU   A HB2  1 c 
ATOM   2775 H HB3  . LEU   A 1 189 ? 28.353  -54.593 112.448 1   130.638 ? 883  LEU   A HB3  1 c 
ATOM   2776 H HG   . LEU   A 1 189 ? 29.195  -52.343 112.019 1   126.556 ? 883  LEU   A HG   1 c 
ATOM   2777 H HD11 . LEU   A 1 189 ? 28.659  -51.105 113.83  1   124.319 ? 883  LEU   A HD11 1 c 
ATOM   2778 H HD12 . LEU   A 1 189 ? 30.212  -51.357 114.048 1   124.412 ? 883  LEU   A HD12 1 c 
ATOM   2779 H HD13 . LEU   A 1 189 ? 29.146  -52.218 114.849 1   124.401 ? 883  LEU   A HD13 1 c 
ATOM   2780 H HD21 . LEU   A 1 189 ? 30.635  -54.178 112.06  1   130.135 ? 883  LEU   A HD21 1 c 
ATOM   2781 H HD22 . LEU   A 1 189 ? 30.778  -54.064 113.636 1   130.132 ? 883  LEU   A HD22 1 c 
ATOM   2782 H HD23 . LEU   A 1 189 ? 31.371  -52.928 112.701 1   130.102 ? 883  LEU   A HD23 1 c 
ATOM   2783 N N    . GLU   A 1 190 ? 26.238  -54.352 110.632 1   117.348 ? 884  GLU   A N    1 ? 
ATOM   2784 C CA   . GLU   A 1 190 ? 25.943  -54.42  109.208 1   115.658 ? 884  GLU   A CA   1 ? 
ATOM   2785 C C    . GLU   A 1 190 ? 24.803  -53.461 108.87  1   117.268 ? 884  GLU   A C    1 ? 
ATOM   2786 O O    . GLU   A 1 190 ? 24.744  -52.928 107.768 1   135.079 ? 884  GLU   A O    1 ? 
ATOM   2787 C CB   . GLU   A 1 190 ? 25.497  -55.829 108.821 1   113.752 ? 884  GLU   A CB   1 ? 
ATOM   2788 C CG   . GLU   A 1 190 ? 25.672  -56.841 109.95  1   121.701 ? 884  GLU   A CG   1 ? 
ATOM   2789 C CD   . GLU   A 1 190 ? 24.477  -57.749 110.131 1   135.748 ? 884  GLU   A CD   1 ? 
ATOM   2790 O OE1  . GLU   A 1 190 ? 23.86   -58.15  109.111 1   128.078 ? 884  GLU   A OE1  1 ? 
ATOM   2791 O OE2  . GLU   A 1 190 ? 24.176  -58.077 111.296 1   154.804 ? 884  GLU   A OE2  1 ? 
ATOM   2792 H H    . GLU   A 1 190 ? 26.24   -55.12  111.124 1   119.658 ? 884  GLU   A H    1 c 
ATOM   2793 H HA   . GLU   A 1 190 ? 26.753  -54.164 108.698 1   115.929 ? 884  GLU   A HA   1 c 
ATOM   2794 H HB2  . GLU   A 1 190 ? 24.556  -55.8   108.549 1   116.124 ? 884  GLU   A HB2  1 c 
ATOM   2795 H HB3  . GLU   A 1 190 ? 26.022  -56.124 108.048 1   115.985 ? 884  GLU   A HB3  1 c 
ATOM   2796 H HG2  . GLU   A 1 190 ? 26.46   -57.396 109.763 1   122.924 ? 884  GLU   A HG2  1 c 
ATOM   2797 H HG3  . GLU   A 1 190 ? 25.831  -56.379 110.792 1   122.996 ? 884  GLU   A HG3  1 c 
ATOM   2798 N N    . SER   A 1 191 ? 23.865  -53.297 109.811 1   126.574 ? 885  SER   A N    1 ? 
ATOM   2799 C CA   . SER   A 1 191 ? 22.731  -52.407 109.652 1   115.498 ? 885  SER   A CA   1 ? 
ATOM   2800 C C    . SER   A 1 191 ? 23.171  -50.963 109.836 1   112.945 ? 885  SER   A C    1 ? 
ATOM   2801 O O    . SER   A 1 191 ? 22.656  -50.095 109.149 1   138.858 ? 885  SER   A O    1 ? 
ATOM   2802 C CB   . SER   A 1 191 ? 21.614  -52.745 110.61  1   125.074 ? 885  SER   A CB   1 ? 
ATOM   2803 O OG   . SER   A 1 191 ? 20.959  -53.944 110.22  1   128.562 ? 885  SER   A OG   1 ? 
ATOM   2804 H H    . SER   A 1 191 ? 23.927  -53.782 110.582 1   121.637 ? 885  SER   A H    1 c 
ATOM   2805 H HA   . SER   A 1 191 ? 22.387  -52.507 108.731 1   119.159 ? 885  SER   A HA   1 c 
ATOM   2806 H HB2  . SER   A 1 191 ? 21.973  -52.847 111.51  1   123.644 ? 885  SER   A HB2  1 c 
ATOM   2807 H HB3  . SER   A 1 191 ? 20.967  -52.018 110.618 1   123.497 ? 885  SER   A HB3  1 c 
ATOM   2808 H HG   . SER   A 1 191 ? 20.337  -54.127 110.772 0   127.9   ? 885  SER   A HG   1 c 
ATOM   2809 N N    . ILE   A 1 192 ? 24.103  -50.706 110.759 1   117.827 ? 886  ILE   A N    1 ? 
ATOM   2810 C CA   . ILE   A 1 192 ? 24.519  -49.339 111.049 1   121.117 ? 886  ILE   A CA   1 ? 
ATOM   2811 C C    . ILE   A 1 192 ? 25.354  -48.795 109.895 1   120.628 ? 886  ILE   A C    1 ? 
ATOM   2812 O O    . ILE   A 1 192 ? 25.142  -47.675 109.452 1   126.027 ? 886  ILE   A O    1 ? 
ATOM   2813 C CB   . ILE   A 1 192 ? 25.306  -49.24  112.365 1   124.407 ? 886  ILE   A CB   1 ? 
ATOM   2814 C CG1  . ILE   A 1 192 ? 24.473  -49.736 113.543 1   134.856 ? 886  ILE   A CG1  1 ? 
ATOM   2815 C CG2  . ILE   A 1 192 ? 25.81   -47.811 112.576 1   125.189 ? 886  ILE   A CG2  1 ? 
ATOM   2816 C CD1  . ILE   A 1 192 ? 25.17   -49.68  114.893 1   144.848 ? 886  ILE   A CD1  1 ? 
ATOM   2817 H H    . ILE   A 1 192 ? 24.485  -51.393 111.224 1   117.732 ? 886  ILE   A H    1 c 
ATOM   2818 H HA   . ILE   A 1 192 ? 23.717  -48.788 111.134 1   121.044 ? 886  ILE   A HA   1 c 
ATOM   2819 H HB   . ILE   A 1 192 ? 26.087  -49.824 112.288 1   125.82  ? 886  ILE   A HB   1 c 
ATOM   2820 H HG12 . ILE   A 1 192 ? 23.655  -49.204 113.59  1   134.511 ? 886  ILE   A HG12 1 c 
ATOM   2821 H HG13 . ILE   A 1 192 ? 24.211  -50.661 113.371 1   134.328 ? 886  ILE   A HG13 1 c 
ATOM   2822 H HG21 . ILE   A 1 192 ? 26.258  -47.744 113.435 1   125.206 ? 886  ILE   A HG21 1 c 
ATOM   2823 H HG22 . ILE   A 1 192 ? 25.059  -47.195 112.556 1   125.118 ? 886  ILE   A HG22 1 c 
ATOM   2824 H HG23 . ILE   A 1 192 ? 26.436  -47.577 111.871 1   125.013 ? 886  ILE   A HG23 1 c 
ATOM   2825 H HD11 . ILE   A 1 192 ? 26.011  -50.172 114.841 1   141.769 ? 886  ILE   A HD11 1 c 
ATOM   2826 H HD12 . ILE   A 1 192 ? 24.597  -50.092 115.567 1   141.769 ? 886  ILE   A HD12 1 c 
ATOM   2827 H HD13 . ILE   A 1 192 ? 25.353  -48.757 115.148 1   141.612 ? 886  ILE   A HD13 1 c 
ATOM   2828 N N    . LEU   A 1 193 ? 26.333  -49.578 109.449 1   124.658 ? 887  LEU   A N    1 ? 
ATOM   2829 C CA   . LEU   A 1 193 ? 27.283  -49.121 108.452 1   125.956 ? 887  LEU   A CA   1 ? 
ATOM   2830 C C    . LEU   A 1 193 ? 26.653  -49.11  107.063 1   115.136 ? 887  LEU   A C    1 ? 
ATOM   2831 O O    . LEU   A 1 193 ? 26.904  -48.183 106.298 1   130.936 ? 887  LEU   A O    1 ? 
ATOM   2832 C CB   . LEU   A 1 193 ? 28.533  -50     108.492 1   130.891 ? 887  LEU   A CB   1 ? 
ATOM   2833 C CG   . LEU   A 1 193 ? 29.292  -49.995 109.824 1   126.58  ? 887  LEU   A CG   1 ? 
ATOM   2834 C CD1  . LEU   A 1 193 ? 30.547  -50.862 109.738 1   126.089 ? 887  LEU   A CD1  1 ? 
ATOM   2835 C CD2  . LEU   A 1 193 ? 29.64   -48.593 110.317 1   117.922 ? 887  LEU   A CD2  1 ? 
ATOM   2836 H H    . LEU   A 1 193 ? 26.417  -50.426 109.78  1   123.972 ? 887  LEU   A H    1 c 
ATOM   2837 H HA   . LEU   A 1 193 ? 27.54   -48.191 108.677 1   124.464 ? 887  LEU   A HA   1 c 
ATOM   2838 H HB2  . LEU   A 1 193 ? 28.266  -50.926 108.288 1   128.807 ? 887  LEU   A HB2  1 c 
ATOM   2839 H HB3  . LEU   A 1 193 ? 29.146  -49.694 107.786 1   128.833 ? 887  LEU   A HB3  1 c 
ATOM   2840 H HG   . LEU   A 1 193 ? 28.7    -50.405 110.506 1   125.577 ? 887  LEU   A HG   1 c 
ATOM   2841 H HD11 . LEU   A 1 193 ? 30.297  -51.775 109.513 1   126.224 ? 887  LEU   A HD11 1 c 
ATOM   2842 H HD12 . LEU   A 1 193 ? 31.006  -50.855 110.594 1   126.193 ? 887  LEU   A HD12 1 c 
ATOM   2843 H HD13 . LEU   A 1 193 ? 31.138  -50.512 109.051 1   126.224 ? 887  LEU   A HD13 1 c 
ATOM   2844 H HD21 . LEU   A 1 193 ? 28.83   -48.135 110.598 1   120.475 ? 887  LEU   A HD21 1 c 
ATOM   2845 H HD22 . LEU   A 1 193 ? 30.063  -48.091 109.599 1   120.433 ? 887  LEU   A HD22 1 c 
ATOM   2846 H HD23 . LEU   A 1 193 ? 30.252  -48.656 111.069 1   120.488 ? 887  LEU   A HD23 1 c 
ATOM   2847 N N    . HIS   A 1 194 ? 25.872  -50.143 106.728 1   118.883 ? 888  HIS   A N    1 ? 
ATOM   2848 C CA   . HIS   A 1 194 ? 25.455  -50.365 105.346 1   126.359 ? 888  HIS   A CA   1 ? 
ATOM   2849 C C    . HIS   A 1 194 ? 23.937  -50.414 105.179 1   116.466 ? 888  HIS   A C    1 ? 
ATOM   2850 O O    . HIS   A 1 194 ? 23.471  -50.713 104.091 1   122.711 ? 888  HIS   A O    1 ? 
ATOM   2851 C CB   . HIS   A 1 194 ? 26.06   -51.653 104.769 1   119.897 ? 888  HIS   A CB   1 ? 
ATOM   2852 C CG   . HIS   A 1 194 ? 27.548  -51.647 104.78  1   127.135 ? 888  HIS   A CG   1 ? 
ATOM   2853 N ND1  . HIS   A 1 194 ? 28.265  -50.731 105.52  1   134.507 ? 888  HIS   A ND1  1 ? 
ATOM   2854 C CD2  . HIS   A 1 194 ? 28.446  -52.404 104.147 1   126.183 ? 888  HIS   A CD2  1 ? 
ATOM   2855 C CE1  . HIS   A 1 194 ? 29.556  -50.949 105.355 1   135.836 ? 888  HIS   A CE1  1 ? 
ATOM   2856 N NE2  . HIS   A 1 194 ? 29.689  -51.959 104.521 1   140.663 ? 888  HIS   A NE2  1 ? 
ATOM   2857 H H    . HIS   A 1 194 ? 25.6    -50.732 107.371 1   119.666 ? 888  HIS   A H    1 c 
ATOM   2858 H HA   . HIS   A 1 194 ? 25.792  -49.61  104.804 1   121.843 ? 888  HIS   A HA   1 c 
ATOM   2859 H HB2  . HIS   A 1 194 ? 25.738  -52.418 105.295 1   123.037 ? 888  HIS   A HB2  1 c 
ATOM   2860 H HB3  . HIS   A 1 194 ? 25.749  -51.764 103.844 1   122.961 ? 888  HIS   A HB3  1 c 
ATOM   2861 H HD1  . HIS   A 1 194 ? 27.936  -50.007 105.953 0   135.36  ? 888  HIS   A HD1  1 c 
ATOM   2862 H HD2  . HIS   A 1 194 ? 28.269  -53.119 103.567 1   129.56  ? 888  HIS   A HD2  1 c 
ATOM   2863 H HE1  . HIS   A 1 194 ? 30.256  -50.46  105.752 1   136.481 ? 888  HIS   A HE1  1 c 
ATOM   2864 H HE2  . HIS   A 1 194 ? 30.473  -52.392 104.427 0   140.37  ? 888  HIS   A HE2  1 c 
ATOM   2865 N N    . ARG   A 1 195 ? 23.163  -50.108 106.224 1   117.563 ? 889  ARG   A N    1 ? 
ATOM   2866 C CA   . ARG   A 1 195 ? 21.71   -50.196 106.143 1   122.362 ? 889  ARG   A CA   1 ? 
ATOM   2867 C C    . ARG   A 1 195 ? 21.269  -51.556 105.599 1   117.428 ? 889  ARG   A C    1 ? 
ATOM   2868 O O    . ARG   A 1 195 ? 20.329  -51.635 104.823 1   116.313 ? 889  ARG   A O    1 ? 
ATOM   2869 C CB   . ARG   A 1 195 ? 21.148  -49.051 105.297 1   128.297 ? 889  ARG   A CB   1 ? 
ATOM   2870 C CG   . ARG   A 1 195 ? 20.347  -48.013 106.072 1   147.837 ? 889  ARG   A CG   1 ? 
ATOM   2871 C CD   . ARG   A 1 195 ? 19.932  -46.848 105.172 1   161.152 ? 889  ARG   A CD   1 ? 
ATOM   2872 N NE   . ARG   A 1 195 ? 21.057  -46.341 104.372 1   165.594 ? 889  ARG   A NE   1 ? 
ATOM   2873 C CZ   . ARG   A 1 195 ? 21.68   -45.167 104.489 1   167.164 ? 889  ARG   A CZ   1 ? 
ATOM   2874 N NH1  . ARG   A 1 195 ? 21.195  -44.214 105.261 1   180.995 ? 889  ARG   A NH1  1 ? 
ATOM   2875 N NH2  . ARG   A 1 195 ? 22.786  -44.934 103.808 1   165.547 ? 889  ARG   A NH2  1 ? 
ATOM   2876 H H    . ARG   A 1 195 ? 23.544  -49.83  107.007 1   118.424 ? 889  ARG   A H    1 c 
ATOM   2877 H HA   . ARG   A 1 195 ? 21.348  -50.102 107.059 1   121.777 ? 889  ARG   A HA   1 c 
ATOM   2878 H HB2  . ARG   A 1 195 ? 21.898  -48.601 104.857 1   131.313 ? 889  ARG   A HB2  1 c 
ATOM   2879 H HB3  . ARG   A 1 195 ? 20.576  -49.423 104.593 1   130.963 ? 889  ARG   A HB3  1 c 
ATOM   2880 H HG2  . ARG   A 1 195 ? 19.542  -48.434 106.446 1   145.961 ? 889  ARG   A HG2  1 c 
ATOM   2881 H HG3  . ARG   A 1 195 ? 20.89   -47.67  106.815 1   145.961 ? 889  ARG   A HG3  1 c 
ATOM   2882 H HD2  . ARG   A 1 195 ? 19.22   -47.148 104.571 1   159.128 ? 889  ARG   A HD2  1 c 
ATOM   2883 H HD3  . ARG   A 1 195 ? 19.572  -46.126 105.725 1   159.36  ? 889  ARG   A HD3  1 c 
ATOM   2884 H HE   . ARG   A 1 195 ? 21.34   -46.854 103.727 1   164.35  ? 889  ARG   A HE   1 c 
ATOM   2885 H HH11 . ARG   A 1 195 ? 20.882  -44.416 106.073 1   176.295 ? 889  ARG   A HH11 1 c 
ATOM   2886 H HH12 . ARG   A 1 195 ? 21.192  -43.369 104.961 1   176.382 ? 889  ARG   A HH12 1 c 
ATOM   2887 H HH21 . ARG   A 1 195 ? 23.071  -45.52  103.21  1   166.068 ? 889  ARG   A HH21 1 c 
ATOM   2888 H HH22 . ARG   A 1 195 ? 23.24   -44.189 103.952 1   166.229 ? 889  ARG   A HH22 1 c 
ATOM   2889 N N    . ILE   A 1 196 ? 21.929  -52.634 106.034 1   126.779 ? 890  ILE   A N    1 ? 
ATOM   2890 C CA   . ILE   A 1 196 ? 21.572  -53.994 105.654 1   128.826 ? 890  ILE   A CA   1 ? 
ATOM   2891 C C    . ILE   A 1 196 ? 20.786  -54.657 106.784 1   126.186 ? 890  ILE   A C    1 ? 
ATOM   2892 O O    . ILE   A 1 196 ? 21.258  -54.73  107.92  1   135.553 ? 890  ILE   A O    1 ? 
ATOM   2893 C CB   . ILE   A 1 196 ? 22.824  -54.833 105.338 1   132.613 ? 890  ILE   A CB   1 ? 
ATOM   2894 C CG1  . ILE   A 1 196 ? 23.228  -54.717 103.88  1   125.908 ? 890  ILE   A CG1  1 ? 
ATOM   2895 C CG2  . ILE   A 1 196 ? 22.605  -56.296 105.74  1   128.891 ? 890  ILE   A CG2  1 ? 
ATOM   2896 C CD1  . ILE   A 1 196 ? 24.557  -55.376 103.563 1   123.013 ? 890  ILE   A CD1  1 ? 
ATOM   2897 H H    . ILE   A 1 196 ? 22.64   -52.515 106.597 1   124.806 ? 890  ILE   A H    1 c 
ATOM   2898 H HA   . ILE   A 1 196 ? 21.012  -53.961 104.855 1   128.197 ? 890  ILE   A HA   1 c 
ATOM   2899 H HB   . ILE   A 1 196 ? 23.561  -54.483 105.877 1   129.901 ? 890  ILE   A HB   1 c 
ATOM   2900 H HG12 . ILE   A 1 196 ? 22.532  -55.128 103.327 1   126.736 ? 890  ILE   A HG12 1 c 
ATOM   2901 H HG13 . ILE   A 1 196 ? 23.28   -53.769 103.642 1   126.736 ? 890  ILE   A HG13 1 c 
ATOM   2902 H HG21 . ILE   A 1 196 ? 23.335  -56.84  105.401 1   129.881 ? 890  ILE   A HG21 1 c 
ATOM   2903 H HG22 . ILE   A 1 196 ? 21.767  -56.617 105.365 1   129.929 ? 890  ILE   A HG22 1 c 
ATOM   2904 H HG23 . ILE   A 1 196 ? 22.578  -56.372 106.708 1   129.954 ? 890  ILE   A HG23 1 c 
ATOM   2905 H HD11 . ILE   A 1 196 ? 25.203  -55.166 104.265 1   123.876 ? 890  ILE   A HD11 1 c 
ATOM   2906 H HD12 . ILE   A 1 196 ? 24.889  -55.042 102.708 1   123.876 ? 890  ILE   A HD12 1 c 
ATOM   2907 H HD13 . ILE   A 1 196 ? 24.442  -56.344 103.508 1   123.927 ? 890  ILE   A HD13 1 c 
ATOM   2908 N N    . TYR   A 1 197 ? 19.636  -55.232 106.431 1   108.877 ? 891  TYR   A N    1 ? 
ATOM   2909 C CA   . TYR   A 1 197 ? 18.799  -55.93  107.384 1   101.244 ? 891  TYR   A CA   1 ? 
ATOM   2910 C C    . TYR   A 1 197 ? 18.475  -57.329 106.887 1   103.862 ? 891  TYR   A C    1 ? 
ATOM   2911 O O    . TYR   A 1 197 ? 18.008  -57.51  105.776 1   119.322 ? 891  TYR   A O    1 ? 
ATOM   2912 C CB   . TYR   A 1 197 ? 17.484  -55.188 107.579 1   107.44  ? 891  TYR   A CB   1 ? 
ATOM   2913 C CG   . TYR   A 1 197 ? 17.651  -53.752 108.053 1   117.559 ? 891  TYR   A CG   1 ? 
ATOM   2914 C CD1  . TYR   A 1 197 ? 17.934  -52.729 107.158 1   124.262 ? 891  TYR   A CD1  1 ? 
ATOM   2915 C CD2  . TYR   A 1 197 ? 17.472  -53.419 109.389 1   123.14  ? 891  TYR   A CD2  1 ? 
ATOM   2916 C CE1  . TYR   A 1 197 ? 18.066  -51.42  107.587 1   126.207 ? 891  TYR   A CE1  1 ? 
ATOM   2917 C CE2  . TYR   A 1 197 ? 17.587  -52.113 109.829 1   114.342 ? 891  TYR   A CE2  1 ? 
ATOM   2918 C CZ   . TYR   A 1 197 ? 17.896  -51.117 108.924 1   118.541 ? 891  TYR   A CZ   1 ? 
ATOM   2919 O OH   . TYR   A 1 197 ? 18.028  -49.838 109.338 1   111.792 ? 891  TYR   A OH   1 ? 
ATOM   2920 H H    . TYR   A 1 197 ? 19.363  -55.188 105.56  1   111.179 ? 891  TYR   A H    1 c 
ATOM   2921 H HA   . TYR   A 1 197 ? 19.271  -55.991 108.256 1   104.646 ? 891  TYR   A HA   1 c 
ATOM   2922 H HB2  . TYR   A 1 197 ? 16.996  -55.186 106.726 1   108.239 ? 891  TYR   A HB2  1 c 
ATOM   2923 H HB3  . TYR   A 1 197 ? 16.942  -55.678 108.236 1   108.313 ? 891  TYR   A HB3  1 c 
ATOM   2924 H HD1  . TYR   A 1 197 ? 18.055  -52.931 106.244 1   122.931 ? 891  TYR   A HD1  1 c 
ATOM   2925 H HD2  . TYR   A 1 197 ? 17.263  -54.098 110.011 1   119.58  ? 891  TYR   A HD2  1 c 
ATOM   2926 H HE1  . TYR   A 1 197 ? 18.273  -50.738 106.971 1   123.712 ? 891  TYR   A HE1  1 c 
ATOM   2927 H HE2  . TYR   A 1 197 ? 17.479  -51.907 110.742 1   117.342 ? 891  TYR   A HE2  1 c 
ATOM   2928 H HH   . TYR   A 1 197 ? 18.214  -49.341 108.737 0   112.2   ? 891  TYR   A HH   1 c 
ATOM   2929 N N    . THR   A 1 198 ? 18.677  -58.315 107.756 1   110.874 ? 892  THR   A N    1 ? 
ATOM   2930 C CA   . THR   A 1 198 ? 18.404  -59.707 107.442 1   114.456 ? 892  THR   A CA   1 ? 
ATOM   2931 C C    . THR   A 1 198 ? 17.839  -60.32  108.713 1   104.653 ? 892  THR   A C    1 ? 
ATOM   2932 O O    . THR   A 1 198 ? 17.812  -59.64  109.727 1   96.857  ? 892  THR   A O    1 ? 
ATOM   2933 C CB   . THR   A 1 198 ? 19.667  -60.421 106.95  1   114.848 ? 892  THR   A CB   1 ? 
ATOM   2934 O OG1  . THR   A 1 198 ? 19.628  -61.786 107.37  1   126.427 ? 892  THR   A OG1  1 ? 
ATOM   2935 C CG2  . THR   A 1 198 ? 20.938  -59.795 107.496 1   114.388 ? 892  THR   A CG2  1 ? 
ATOM   2936 H H    . THR   A 1 198 ? 18.978  -58.109 108.593 1   109.744 ? 892  THR   A H    1 c 
ATOM   2937 H HA   . THR   A 1 198 ? 17.721  -59.746 106.738 1   112.175 ? 892  THR   A HA   1 c 
ATOM   2938 H HB   . THR   A 1 198 ? 19.696  -60.387 105.964 1   116.863 ? 892  THR   A HB   1 c 
ATOM   2939 H HG1  . THR   A 1 198 ? 19.573  -61.85  108.259 0   128.31  ? 892  THR   A HG1  1 c 
ATOM   2940 H HG21 . THR   A 1 198 ? 21.704  -60.325 107.219 1   114.458 ? 892  THR   A HG21 1 c 
ATOM   2941 H HG22 . THR   A 1 198 ? 20.898  -59.77  108.464 1   114.265 ? 892  THR   A HG22 1 c 
ATOM   2942 H HG23 . THR   A 1 198 ? 21.031  -58.891 107.152 1   114.44  ? 892  THR   A HG23 1 c 
ATOM   2943 N N    . HIS   A 1 199 ? 17.379  -61.575 108.619 1   110.521 ? 893  HIS   A N    1 ? 
ATOM   2944 C CA   . HIS   A 1 199 ? 16.91   -62.325 109.771 1   107.462 ? 893  HIS   A CA   1 ? 
ATOM   2945 C C    . HIS   A 1 199 ? 18.012  -62.338 110.827 1   103.141 ? 893  HIS   A C    1 ? 
ATOM   2946 O O    . HIS   A 1 199 ? 17.741  -62.207 112.015 1   101.62  ? 893  HIS   A O    1 ? 
ATOM   2947 C CB   . HIS   A 1 199 ? 16.495  -63.745 109.358 1   110.115 ? 893  HIS   A CB   1 ? 
ATOM   2948 C CG   . HIS   A 1 199 ? 15.334  -63.805 108.41  1   116.149 ? 893  HIS   A CG   1 ? 
ATOM   2949 N ND1  . HIS   A 1 199 ? 14.249  -62.956 108.47  1   115.873 ? 893  HIS   A ND1  1 ? 
ATOM   2950 C CD2  . HIS   A 1 199 ? 15.069  -64.653 107.405 1   114.503 ? 893  HIS   A CD2  1 ? 
ATOM   2951 C CE1  . HIS   A 1 199 ? 13.393  -63.261 107.506 1   114.176 ? 893  HIS   A CE1  1 ? 
ATOM   2952 N NE2  . HIS   A 1 199 ? 13.869  -64.288 106.843 1   111.963 ? 893  HIS   A NE2  1 ? 
ATOM   2953 H H    . HIS   A 1 199 ? 17.363  -61.978 107.799 1   108.496 ? 893  HIS   A H    1 c 
ATOM   2954 H HA   . HIS   A 1 199 ? 16.126  -61.855 110.146 1   107.731 ? 893  HIS   A HA   1 c 
ATOM   2955 H HB2  . HIS   A 1 199 ? 17.267  -64.187 108.942 1   110.873 ? 893  HIS   A HB2  1 c 
ATOM   2956 H HB3  . HIS   A 1 199 ? 16.268  -64.252 110.168 1   110.873 ? 893  HIS   A HB3  1 c 
ATOM   2957 H HD1  . HIS   A 1 199 ? 14.138  -62.268 109.055 0   117.73  ? 893  HIS   A HD1  1 c 
ATOM   2958 H HD2  . HIS   A 1 199 ? 15.618  -65.352 107.108 1   114.283 ? 893  HIS   A HD2  1 c 
ATOM   2959 H HE1  . HIS   A 1 199 ? 12.58   -62.822 107.334 1   114.099 ? 893  HIS   A HE1  1 c 
ATOM   2960 H HE2  . HIS   A 1 199 ? 13.489  -64.679 106.169 0   112.33  ? 893  HIS   A HE2  1 c 
ATOM   2961 N N    . GLN   A 1 200 ? 19.259  -62.499 110.363 1   113.98  ? 894  GLN   A N    1 ? 
ATOM   2962 C CA   . GLN   A 1 200 ? 20.432  -62.575 111.222 1   111.998 ? 894  GLN   A CA   1 ? 
ATOM   2963 C C    . GLN   A 1 200 ? 20.692  -61.234 111.915 1   93.045  ? 894  GLN   A C    1 ? 
ATOM   2964 O O    . GLN   A 1 200 ? 21.092  -61.173 113.071 1   110.478 ? 894  GLN   A O    1 ? 
ATOM   2965 C CB   . GLN   A 1 200 ? 21.614  -63.084 110.394 1   110.418 ? 894  GLN   A CB   1 ? 
ATOM   2966 C CG   . GLN   A 1 200 ? 21.499  -64.561 110.022 1   118.837 ? 894  GLN   A CG   1 ? 
ATOM   2967 C CD   . GLN   A 1 200 ? 21.064  -65.449 111.18  1   137.321 ? 894  GLN   A CD   1 ? 
ATOM   2968 O OE1  . GLN   A 1 200 ? 21.778  -65.602 112.178 1   123.909 ? 894  GLN   A OE1  1 ? 
ATOM   2969 N NE2  . GLN   A 1 200 ? 19.88   -66.045 111.087 1   138.383 ? 894  GLN   A NE2  1 ? 
ATOM   2970 H H    . GLN   A 1 200 ? 19.381  -62.58  109.461 1   110.808 ? 894  GLN   A H    1 c 
ATOM   2971 H HA   . GLN   A 1 200 ? 20.243  -63.242 111.928 1   108.399 ? 894  GLN   A HA   1 c 
ATOM   2972 H HB2  . GLN   A 1 200 ? 21.682  -62.551 109.575 1   112.618 ? 894  GLN   A HB2  1 c 
ATOM   2973 H HB3  . GLN   A 1 200 ? 22.438  -62.948 110.907 1   112.597 ? 894  GLN   A HB3  1 c 
ATOM   2974 H HG2  . GLN   A 1 200 ? 20.854  -64.658 109.289 1   121.009 ? 894  GLN   A HG2  1 c 
ATOM   2975 H HG3  . GLN   A 1 200 ? 22.368  -64.878 109.695 1   120.844 ? 894  GLN   A HG3  1 c 
ATOM   2976 H HE21 . GLN   A 1 200 ? 19.618  -66.606 111.722 1   137.868 ? 894  GLN   A HE21 1 c 
ATOM   2977 H HE22 . GLN   A 1 200 ? 19.35   -65.882 110.394 1   137.72  ? 894  GLN   A HE22 1 c 
ATOM   2978 N N    . SER   A 1 201 ? 20.435  -60.144 111.216 1   96.39   ? 895  SER   A N    1 ? 
ATOM   2979 C CA   . SER   A 1 201 ? 20.553  -58.816 111.8   1   101.747 ? 895  SER   A CA   1 ? 
ATOM   2980 C C    . SER   A 1 201 ? 19.484  -58.66  112.876 1   94.686  ? 895  SER   A C    1 ? 
ATOM   2981 O O    . SER   A 1 201 ? 19.663  -57.96  113.861 1   91.384  ? 895  SER   A O    1 ? 
ATOM   2982 C CB   . SER   A 1 201 ? 20.412  -57.736 110.736 1   106.322 ? 895  SER   A CB   1 ? 
ATOM   2983 O OG   . SER   A 1 201 ? 19.158  -57.067 110.817 1   102.428 ? 895  SER   A OG   1 ? 
ATOM   2984 H H    . SER   A 1 201 ? 20.17   -60.221 110.346 1   97.278  ? 895  SER   A H    1 c 
ATOM   2985 H HA   . SER   A 1 201 ? 21.445  -58.733 112.223 1   100.181 ? 895  SER   A HA   1 c 
ATOM   2986 H HB2  . SER   A 1 201 ? 21.129  -57.084 110.849 1   104.344 ? 895  SER   A HB2  1 c 
ATOM   2987 H HB3  . SER   A 1 201 ? 20.511  -58.136 109.855 1   104.355 ? 895  SER   A HB3  1 c 
ATOM   2988 H HG   . SER   A 1 201 ? 19.139  -56.518 110.192 0   102.27  ? 895  SER   A HG   1 c 
ATOM   2989 N N    . ASP   A 1 202 ? 18.347  -59.306 112.63  1   105.656 ? 896  ASP   A N    1 ? 
ATOM   2990 C CA   . ASP   A 1 202 ? 17.242  -59.386 113.569 1   110.157 ? 896  ASP   A CA   1 ? 
ATOM   2991 C C    . ASP   A 1 202 ? 17.646  -60.115 114.846 1   107.702 ? 896  ASP   A C    1 ? 
ATOM   2992 O O    . ASP   A 1 202 ? 17.202  -59.758 115.94  1   97.983  ? 896  ASP   A O    1 ? 
ATOM   2993 C CB   . ASP   A 1 202 ? 16.066  -60.097 112.924 1   106.633 ? 896  ASP   A CB   1 ? 
ATOM   2994 C CG   . ASP   A 1 202 ? 14.991  -59.16  112.418 1   95.178  ? 896  ASP   A CG   1 ? 
ATOM   2995 O OD1  . ASP   A 1 202 ? 15.297  -57.978 112.173 1   97.521  ? 896  ASP   A OD1  1 ? 
ATOM   2996 O OD2  . ASP   A 1 202 ? 13.857  -59.617 112.345 1   110.264 ? 896  ASP   A OD2  1 ? 
ATOM   2997 H H    . ASP   A 1 202 ? 18.245  -59.705 111.814 1   103.797 ? 896  ASP   A H    1 c 
ATOM   2998 H HA   . ASP   A 1 202 ? 16.973  -58.471 113.807 1   108.02  ? 896  ASP   A HA   1 c 
ATOM   2999 H HB2  . ASP   A 1 202 ? 16.366  -60.621 112.159 1   104.586 ? 896  ASP   A HB2  1 c 
ATOM   3000 H HB3  . ASP   A 1 202 ? 15.659  -60.71  113.571 1   104.673 ? 896  ASP   A HB3  1 c 
ATOM   3001 N N    . VAL   A 1 203 ? 18.461  -61.161 114.674 1   110.976 ? 897  VAL   A N    1 ? 
ATOM   3002 C CA   . VAL   A 1 203 ? 18.951  -61.963 115.786 1   98.272  ? 897  VAL   A CA   1 ? 
ATOM   3003 C C    . VAL   A 1 203 ? 19.749  -61.099 116.763 1   94.7    ? 897  VAL   A C    1 ? 
ATOM   3004 O O    . VAL   A 1 203 ? 19.632  -61.24  117.972 1   101.381 ? 897  VAL   A O    1 ? 
ATOM   3005 C CB   . VAL   A 1 203 ? 19.79   -63.143 115.268 1   91.157  ? 897  VAL   A CB   1 ? 
ATOM   3006 C CG1  . VAL   A 1 203 ? 20.712  -63.701 116.34  1   97.399  ? 897  VAL   A CG1  1 ? 
ATOM   3007 C CG2  . VAL   A 1 203 ? 18.895  -64.232 114.688 1   105.572 ? 897  VAL   A CG2  1 ? 
ATOM   3008 H H    . VAL   A 1 203 ? 18.71   -61.394 113.827 1   106.911 ? 897  VAL   A H    1 c 
ATOM   3009 H HA   . VAL   A 1 203 ? 18.177  -62.324 116.26  1   98.611  ? 897  VAL   A HA   1 c 
ATOM   3010 H HB   . VAL   A 1 203 ? 20.356  -62.802 114.54  1   96.343  ? 897  VAL   A HB   1 c 
ATOM   3011 H HG11 . VAL   A 1 203 ? 20.198  -63.896 117.143 1   95.495  ? 897  VAL   A HG11 1 c 
ATOM   3012 H HG12 . VAL   A 1 203 ? 21.404  -63.052 116.548 1   95.496  ? 897  VAL   A HG12 1 c 
ATOM   3013 H HG13 . VAL   A 1 203 ? 21.127  -64.517 116.017 1   95.461  ? 897  VAL   A HG13 1 c 
ATOM   3014 H HG21 . VAL   A 1 203 ? 19.445  -64.942 114.319 1   101.019 ? 897  VAL   A HG21 1 c 
ATOM   3015 H HG22 . VAL   A 1 203 ? 18.339  -63.856 113.986 1   101.078 ? 897  VAL   A HG22 1 c 
ATOM   3016 H HG23 . VAL   A 1 203 ? 18.328  -64.594 115.39  1   101.076 ? 897  VAL   A HG23 1 c 
ATOM   3017 N N    . TRP   A 1 204 ? 20.584  -60.211 116.239 1   98.787  ? 898  TRP   A N    1 ? 
ATOM   3018 C CA   . TRP   A 1 204 ? 21.368  -59.318 117.073 1   92.385  ? 898  TRP   A CA   1 ? 
ATOM   3019 C C    . TRP   A 1 204 ? 20.448  -58.468 117.939 1   87.72   ? 898  TRP   A C    1 ? 
ATOM   3020 O O    . TRP   A 1 204 ? 20.697  -58.272 119.122 1   92.863  ? 898  TRP   A O    1 ? 
ATOM   3021 C CB   . TRP   A 1 204 ? 22.258  -58.451 116.175 1   100.729 ? 898  TRP   A CB   1 ? 
ATOM   3022 C CG   . TRP   A 1 204 ? 22.997  -57.353 116.888 1   95.859  ? 898  TRP   A CG   1 ? 
ATOM   3023 C CD1  . TRP   A 1 204 ? 22.485  -56.392 117.711 1   91.901  ? 898  TRP   A CD1  1 ? 
ATOM   3024 C CD2  . TRP   A 1 204 ? 24.418  -57.114 116.818 1   93.223  ? 898  TRP   A CD2  1 ? 
ATOM   3025 N NE1  . TRP   A 1 204 ? 23.484  -55.575 118.166 1   87.453  ? 898  TRP   A NE1  1 ? 
ATOM   3026 C CE2  . TRP   A 1 204 ? 24.677  -55.995 117.64  1   88.863  ? 898  TRP   A CE2  1 ? 
ATOM   3027 C CE3  . TRP   A 1 204 ? 25.482  -57.734 116.151 1   89.021  ? 898  TRP   A CE3  1 ? 
ATOM   3028 C CZ2  . TRP   A 1 204 ? 25.96   -55.488 117.81  1   91.813  ? 898  TRP   A CZ2  1 ? 
ATOM   3029 C CZ3  . TRP   A 1 204 ? 26.749  -57.223 116.319 1   101.821 ? 898  TRP   A CZ3  1 ? 
ATOM   3030 C CH2  . TRP   A 1 204 ? 26.985  -56.115 117.138 1   96.881  ? 898  TRP   A CH2  1 ? 
ATOM   3031 H H    . TRP   A 1 204 ? 20.677  -60.161 115.332 1   96.472  ? 898  TRP   A H    1 c 
ATOM   3032 H HA   . TRP   A 1 204 ? 21.95   -59.865 117.664 1   94.259  ? 898  TRP   A HA   1 c 
ATOM   3033 H HB2  . TRP   A 1 204 ? 22.91   -59.033 115.73  1   97.641  ? 898  TRP   A HB2  1 c 
ATOM   3034 H HB3  . TRP   A 1 204 ? 21.697  -58.05  115.477 1   97.606  ? 898  TRP   A HB3  1 c 
ATOM   3035 H HD1  . TRP   A 1 204 ? 21.578  -56.291 117.943 1   91.72   ? 898  TRP   A HD1  1 c 
ATOM   3036 H HE1  . TRP   A 1 204 ? 23.377  -54.899 118.707 1   88.919  ? 898  TRP   A HE1  1 c 
ATOM   3037 H HE3  . TRP   A 1 204 ? 25.331  -58.481 115.597 1   92.827  ? 898  TRP   A HE3  1 c 
ATOM   3038 H HZ2  . TRP   A 1 204 ? 26.116  -54.745 118.362 1   93.042  ? 898  TRP   A HZ2  1 c 
ATOM   3039 H HZ3  . TRP   A 1 204 ? 27.475  -57.633 115.878 1   97.388  ? 898  TRP   A HZ3  1 c 
ATOM   3040 H HH2  . TRP   A 1 204 ? 27.864  -55.796 117.237 1   96.888  ? 898  TRP   A HH2  1 c 
ATOM   3041 N N    . SER   A 1 205 ? 19.387  -57.947 117.327 1   94.054  ? 899  SER   A N    1 ? 
ATOM   3042 C CA   . SER   A 1 205 ? 18.42   -57.144 118.052 1   103.191 ? 899  SER   A CA   1 ? 
ATOM   3043 C C    . SER   A 1 205 ? 17.743  -57.975 119.135 1   99.335  ? 899  SER   A C    1 ? 
ATOM   3044 O O    . SER   A 1 205 ? 17.404  -57.473 120.199 1   102.086 ? 899  SER   A O    1 ? 
ATOM   3045 C CB   . SER   A 1 205 ? 17.417  -56.566 117.12  1   111.613 ? 899  SER   A CB   1 ? 
ATOM   3046 O OG   . SER   A 1 205 ? 17.942  -55.388 116.536 1   122.837 ? 899  SER   A OG   1 ? 
ATOM   3047 H H    . SER   A 1 205 ? 19.265  -58.087 116.432 1   94.712  ? 899  SER   A H    1 c 
ATOM   3048 H HA   . SER   A 1 205 ? 18.905  -56.4   118.492 1   102.025 ? 899  SER   A HA   1 c 
ATOM   3049 H HB2  . SER   A 1 205 ? 17.204  -57.213 116.422 1   111.775 ? 899  SER   A HB2  1 c 
ATOM   3050 H HB3  . SER   A 1 205 ? 16.6    -56.354 117.609 1   111.905 ? 899  SER   A HB3  1 c 
ATOM   3051 H HG   . SER   A 1 205 ? 17.369  -55.092 115.974 0   121.8   ? 899  SER   A HG   1 c 
ATOM   3052 N N    . TYR   A 1 206 ? 17.555  -59.258 118.843 1   103.712 ? 900  TYR   A N    1 ? 
ATOM   3053 C CA   . TYR   A 1 206 ? 16.995  -60.199 119.796 1   104.078 ? 900  TYR   A CA   1 ? 
ATOM   3054 C C    . TYR   A 1 206 ? 17.871  -60.29  121.034 1   92.443  ? 900  TYR   A C    1 ? 
ATOM   3055 O O    . TYR   A 1 206 ? 17.342  -60.325 122.139 1   100.32  ? 900  TYR   A O    1 ? 
ATOM   3056 C CB   . TYR   A 1 206 ? 16.902  -61.581 119.153 1   107.326 ? 900  TYR   A CB   1 ? 
ATOM   3057 C CG   . TYR   A 1 206 ? 16.451  -62.667 120.104 1   93.688  ? 900  TYR   A CG   1 ? 
ATOM   3058 C CD1  . TYR   A 1 206 ? 15.226  -62.581 120.73  1   95.919  ? 900  TYR   A CD1  1 ? 
ATOM   3059 C CD2  . TYR   A 1 206 ? 17.25   -63.76  120.377 1   92.424  ? 900  TYR   A CD2  1 ? 
ATOM   3060 C CE1  . TYR   A 1 206 ? 14.797  -63.567 121.597 1   98.47   ? 900  TYR   A CE1  1 ? 
ATOM   3061 C CE2  . TYR   A 1 206 ? 16.834  -64.749 121.249 1   93.071  ? 900  TYR   A CE2  1 ? 
ATOM   3062 C CZ   . TYR   A 1 206 ? 15.595  -64.663 121.851 1   88.588  ? 900  TYR   A CZ   1 ? 
ATOM   3063 O OH   . TYR   A 1 206 ? 15.171  -65.626 122.716 1   89.141  ? 900  TYR   A OH   1 ? 
ATOM   3064 H H    . TYR   A 1 206 ? 17.765  -59.56  118.006 1   102.577 ? 900  TYR   A H    1 c 
ATOM   3065 H HA   . TYR   A 1 206 ? 16.085  -59.896 120.058 1   102.314 ? 900  TYR   A HA   1 c 
ATOM   3066 H HB2  . TYR   A 1 206 ? 16.271  -61.533 118.401 1   103.226 ? 900  TYR   A HB2  1 c 
ATOM   3067 H HB3  . TYR   A 1 206 ? 17.782  -61.82  118.795 1   103.096 ? 900  TYR   A HB3  1 c 
ATOM   3068 H HD1  . TYR   A 1 206 ? 14.665  -61.842 120.554 1   95.951  ? 900  TYR   A HD1  1 c 
ATOM   3069 H HD2  . TYR   A 1 206 ? 18.094  -63.835 119.96  1   93.028  ? 900  TYR   A HD2  1 c 
ATOM   3070 H HE1  . TYR   A 1 206 ? 13.955  -63.496 122.012 1   95.331  ? 900  TYR   A HE1  1 c 
ATOM   3071 H HE2  . TYR   A 1 206 ? 17.386  -65.492 121.417 1   91.916  ? 900  TYR   A HE2  1 c 
ATOM   3072 H HH   . TYR   A 1 206 ? 14.412  -65.417 123.066 0   90.58   ? 900  TYR   A HH   1 c 
ATOM   3073 N N    . GLY   A 1 207 ? 19.194  -60.318 120.819 1   94.856  ? 901  GLY   A N    1 ? 
ATOM   3074 C CA   . GLY   A 1 207 ? 20.175  -60.369 121.889 1   95.578  ? 901  GLY   A CA   1 ? 
ATOM   3075 C C    . GLY   A 1 207 ? 20.096  -59.144 122.8   1   91.733  ? 901  GLY   A C    1 ? 
ATOM   3076 O O    . GLY   A 1 207 ? 20.224  -59.257 124.018 1   91.551  ? 901  GLY   A O    1 ? 
ATOM   3077 H H    . GLY   A 1 207 ? 19.498  -60.315 119.957 1   94.527  ? 901  GLY   A H    1 c 
ATOM   3078 H HA2  . GLY   A 1 207 ? 20.025  -61.184 122.423 1   94.537  ? 901  GLY   A HA2  1 c 
ATOM   3079 H HA3  . GLY   A 1 207 ? 21.077  -60.426 121.495 1   94.537  ? 901  GLY   A HA3  1 c 
ATOM   3080 N N    . VAL   A 1 208 ? 19.918  -57.97  122.199 1   89.587  ? 902  VAL   A N    1 ? 
ATOM   3081 C CA   . VAL   A 1 208 ? 19.786  -56.749 122.973 1   94.056  ? 902  VAL   A CA   1 ? 
ATOM   3082 C C    . VAL   A 1 208 ? 18.494  -56.8   123.778 1   90.949  ? 902  VAL   A C    1 ? 
ATOM   3083 O O    . VAL   A 1 208 ? 18.434  -56.347 124.917 1   94.695  ? 902  VAL   A O    1 ? 
ATOM   3084 C CB   . VAL   A 1 208 ? 19.815  -55.496 122.082 1   92.935  ? 902  VAL   A CB   1 ? 
ATOM   3085 C CG1  . VAL   A 1 208 ? 19.7    -54.22  122.914 1   88.16   ? 902  VAL   A CG1  1 ? 
ATOM   3086 C CG2  . VAL   A 1 208 ? 21.059  -55.462 121.198 1   91.106  ? 902  VAL   A CG2  1 ? 
ATOM   3087 H H    . VAL   A 1 208 ? 19.869  -57.928 121.287 1   91.156  ? 902  VAL   A H    1 c 
ATOM   3088 H HA   . VAL   A 1 208 ? 20.536  -56.7   123.596 1   92.382  ? 902  VAL   A HA   1 c 
ATOM   3089 H HB   . VAL   A 1 208 ? 19.027  -55.542 121.491 1   91.892  ? 902  VAL   A HB   1 c 
ATOM   3090 H HG11 . VAL   A 1 208 ? 20.351  -54.243 123.636 1   89.542  ? 902  VAL   A HG11 1 c 
ATOM   3091 H HG12 . VAL   A 1 208 ? 18.805  -54.151 123.287 1   89.547  ? 902  VAL   A HG12 1 c 
ATOM   3092 H HG13 . VAL   A 1 208 ? 19.873  -53.448 122.349 1   89.553  ? 902  VAL   A HG13 1 c 
ATOM   3093 H HG21 . VAL   A 1 208 ? 21.121  -54.599 120.757 1   91.666  ? 902  VAL   A HG21 1 c 
ATOM   3094 H HG22 . VAL   A 1 208 ? 21.003  -56.163 120.528 1   91.639  ? 902  VAL   A HG22 1 c 
ATOM   3095 H HG23 . VAL   A 1 208 ? 21.85   -55.602 121.746 1   91.645  ? 902  VAL   A HG23 1 c 
ATOM   3096 N N    . THR   A 1 209 ? 17.446  -57.327 123.147 1   97.07   ? 903  THR   A N    1 ? 
ATOM   3097 C CA   . THR   A 1 209 ? 16.15   -57.45  123.784 1   93.735  ? 903  THR   A CA   1 ? 
ATOM   3098 C C    . THR   A 1 209 ? 16.293  -58.331 125.016 1   93.294  ? 903  THR   A C    1 ? 
ATOM   3099 O O    . THR   A 1 209 ? 15.709  -58.05  126.054 1   96.557  ? 903  THR   A O    1 ? 
ATOM   3100 C CB   . THR   A 1 209 ? 15.132  -58.051 122.818 1   89.393  ? 903  THR   A CB   1 ? 
ATOM   3101 O OG1  . THR   A 1 209 ? 15.003  -57.134 121.738 1   90.043  ? 903  THR   A OG1  1 ? 
ATOM   3102 C CG2  . THR   A 1 209 ? 13.785  -58.262 123.483 1   92.216  ? 903  THR   A CG2  1 ? 
ATOM   3103 H H    . THR   A 1 209 ? 17.539  -57.614 122.284 1   94.738  ? 903  THR   A H    1 c 
ATOM   3104 H HA   . THR   A 1 209 ? 15.845  -56.559 124.057 1   93.574  ? 903  THR   A HA   1 c 
ATOM   3105 H HB   . THR   A 1 209 ? 15.461  -58.915 122.476 1   90.865  ? 903  THR   A HB   1 c 
ATOM   3106 H HG1  . THR   A 1 209 ? 14.715  -56.383 122.026 0   89.36   ? 903  THR   A HG1  1 c 
ATOM   3107 H HG21 . THR   A 1 209 ? 13.118  -58.466 122.806 1   91.373  ? 903  THR   A HG21 1 c 
ATOM   3108 H HG22 . THR   A 1 209 ? 13.527  -57.454 123.958 1   91.374  ? 903  THR   A HG22 1 c 
ATOM   3109 H HG23 . THR   A 1 209 ? 13.843  -59.002 124.111 1   91.382  ? 903  THR   A HG23 1 c 
ATOM   3110 N N    . VAL   A 1 210 ? 17.008  -59.446 124.864 1   104.229 ? 904  VAL   A N    1 ? 
ATOM   3111 C CA   . VAL   A 1 210 ? 17.158  -60.397 125.953 1   97.268  ? 904  VAL   A CA   1 ? 
ATOM   3112 C C    . VAL   A 1 210 ? 17.914  -59.732 127.087 1   92.224  ? 904  VAL   A C    1 ? 
ATOM   3113 O O    . VAL   A 1 210 ? 17.594  -59.943 128.248 1   102.254 ? 904  VAL   A O    1 ? 
ATOM   3114 C CB   . VAL   A 1 210 ? 17.876  -61.674 125.505 1   94.185  ? 904  VAL   A CB   1 ? 
ATOM   3115 C CG1  . VAL   A 1 210 ? 18.45   -62.434 126.685 1   92.215  ? 904  VAL   A CG1  1 ? 
ATOM   3116 C CG2  . VAL   A 1 210 ? 16.947  -62.549 124.67  1   107.628 ? 904  VAL   A CG2  1 ? 
ATOM   3117 H H    . VAL   A 1 210 ? 17.406  -59.625 124.062 1   99.812  ? 904  VAL   A H    1 c 
ATOM   3118 H HA   . VAL   A 1 210 ? 16.268  -60.64  126.274 1   97.071  ? 904  VAL   A HA   1 c 
ATOM   3119 H HB   . VAL   A 1 210 ? 18.629  -61.398 124.93  1   96.763  ? 904  VAL   A HB   1 c 
ATOM   3120 H HG11 . VAL   A 1 210 ? 17.74   -62.638 127.316 1   92.891  ? 904  VAL   A HG11 1 c 
ATOM   3121 H HG12 . VAL   A 1 210 ? 19.124  -61.891 127.122 1   93.164  ? 904  VAL   A HG12 1 c 
ATOM   3122 H HG13 . VAL   A 1 210 ? 18.855  -63.261 126.374 1   92.883  ? 904  VAL   A HG13 1 c 
ATOM   3123 H HG21 . VAL   A 1 210 ? 17.416  -63.358 124.402 1   103.453 ? 904  VAL   A HG21 1 c 
ATOM   3124 H HG22 . VAL   A 1 210 ? 16.665  -62.063 123.878 1   103.439 ? 904  VAL   A HG22 1 c 
ATOM   3125 H HG23 . VAL   A 1 210 ? 16.166  -62.788 125.196 1   103.405 ? 904  VAL   A HG23 1 c 
ATOM   3126 N N    . TRP   A 1 211 ? 18.914  -58.934 126.719 1   92.389  ? 905  TRP   A N    1 ? 
ATOM   3127 C CA   . TRP   A 1 211 ? 19.714  -58.194 127.676 1   93.739  ? 905  TRP   A CA   1 ? 
ATOM   3128 C C    . TRP   A 1 211 ? 18.837  -57.245 128.478 1   88.755  ? 905  TRP   A C    1 ? 
ATOM   3129 O O    . TRP   A 1 211 ? 19.057  -57.094 129.671 1   96.081  ? 905  TRP   A O    1 ? 
ATOM   3130 C CB   . TRP   A 1 211 ? 20.82   -57.43  126.944 1   97.208  ? 905  TRP   A CB   1 ? 
ATOM   3131 C CG   . TRP   A 1 211 ? 21.818  -56.787 127.858 1   93.908  ? 905  TRP   A CG   1 ? 
ATOM   3132 C CD1  . TRP   A 1 211 ? 22.976  -57.327 128.325 1   105.027 ? 905  TRP   A CD1  1 ? 
ATOM   3133 C CD2  . TRP   A 1 211 ? 21.747  -55.458 128.394 1   96.853  ? 905  TRP   A CD2  1 ? 
ATOM   3134 N NE1  . TRP   A 1 211 ? 23.633  -56.427 129.121 1   102.66  ? 905  TRP   A NE1  1 ? 
ATOM   3135 C CE2  . TRP   A 1 211 ? 22.904  -55.27  129.182 1   102.983 ? 905  TRP   A CE2  1 ? 
ATOM   3136 C CE3  . TRP   A 1 211 ? 20.819  -54.423 128.289 1   100.664 ? 905  TRP   A CE3  1 ? 
ATOM   3137 C CZ2  . TRP   A 1 211 ? 23.159  -54.077 129.857 1   108.174 ? 905  TRP   A CZ2  1 ? 
ATOM   3138 C CZ3  . TRP   A 1 211 ? 21.069  -53.248 128.962 1   109.381 ? 905  TRP   A CZ3  1 ? 
ATOM   3139 C CH2  . TRP   A 1 211 ? 22.222  -53.076 129.734 1   105.733 ? 905  TRP   A CH2  1 ? 
ATOM   3140 H H    . TRP   A 1 211 ? 19.113  -58.852 125.831 1   92.818  ? 905  TRP   A H    1 c 
ATOM   3141 H HA   . TRP   A 1 211 ? 20.138  -58.843 128.3   1   93.158  ? 905  TRP   A HA   1 c 
ATOM   3142 H HB2  . TRP   A 1 211 ? 21.29   -58.054 126.35  1   95.623  ? 905  TRP   A HB2  1 c 
ATOM   3143 H HB3  . TRP   A 1 211 ? 20.406  -56.736 126.389 1   95.633  ? 905  TRP   A HB3  1 c 
ATOM   3144 H HD1  . TRP   A 1 211 ? 23.291  -58.195 128.13  1   101.819 ? 905  TRP   A HD1  1 c 
ATOM   3145 H HE1  . TRP   A 1 211 ? 24.395  -56.569 129.522 1   103.209 ? 905  TRP   A HE1  1 c 
ATOM   3146 H HE3  . TRP   A 1 211 ? 20.039  -54.528 127.771 1   101.775 ? 905  TRP   A HE3  1 c 
ATOM   3147 H HZ2  . TRP   A 1 211 ? 23.934  -53.966 130.38  1   106.236 ? 905  TRP   A HZ2  1 c 
ATOM   3148 H HZ3  . TRP   A 1 211 ? 20.451  -52.539 128.895 1   106.322 ? 905  TRP   A HZ3  1 c 
ATOM   3149 H HH2  . TRP   A 1 211 ? 22.362  -52.258 130.178 1   106.997 ? 905  TRP   A HH2  1 c 
ATOM   3150 N N    . GLU   A 1 212 ? 17.866  -56.608 127.821 1   89.916  ? 906  GLU   A N    1 ? 
ATOM   3151 C CA   . GLU   A 1 212 ? 16.987  -55.672 128.496 1   97.09   ? 906  GLU   A CA   1 ? 
ATOM   3152 C C    . GLU   A 1 212 ? 16.188  -56.384 129.582 1   91.358  ? 906  GLU   A C    1 ? 
ATOM   3153 O O    . GLU   A 1 212 ? 15.98   -55.84  130.656 1   103.309 ? 906  GLU   A O    1 ? 
ATOM   3154 C CB   . GLU   A 1 212 ? 16.003  -55.025 127.525 1   113.66  ? 906  GLU   A CB   1 ? 
ATOM   3155 C CG   . GLU   A 1 212 ? 16.655  -54.131 126.477 1   114.873 ? 906  GLU   A CG   1 ? 
ATOM   3156 C CD   . GLU   A 1 212 ? 15.621  -53.538 125.535 1   112.272 ? 906  GLU   A CD   1 ? 
ATOM   3157 O OE1  . GLU   A 1 212 ? 15.413  -54.106 124.442 1   111.796 ? 906  GLU   A OE1  1 ? 
ATOM   3158 O OE2  . GLU   A 1 212 ? 15.022  -52.508 125.895 1   109.568 ? 906  GLU   A OE2  1 ? 
ATOM   3159 H H    . GLU   A 1 212 ? 17.752  -56.755 126.926 1   91.631  ? 906  GLU   A H    1 c 
ATOM   3160 H HA   . GLU   A 1 212 ? 17.542  -54.966 128.915 1   97.417  ? 906  GLU   A HA   1 c 
ATOM   3161 H HB2  . GLU   A 1 212 ? 15.499  -55.73  127.07  1   109.801 ? 906  GLU   A HB2  1 c 
ATOM   3162 H HB3  . GLU   A 1 212 ? 15.364  -54.487 128.038 1   109.777 ? 906  GLU   A HB3  1 c 
ATOM   3163 H HG2  . GLU   A 1 212 ? 17.136  -53.401 126.922 1   113.937 ? 906  GLU   A HG2  1 c 
ATOM   3164 H HG3  . GLU   A 1 212 ? 17.299  -54.651 125.956 1   113.683 ? 906  GLU   A HG3  1 c 
ATOM   3165 N N    . LEU   A 1 213 ? 15.717  -57.595 129.293 1   91.443  ? 907  LEU   A N    1 ? 
ATOM   3166 C CA   . LEU   A 1 213 ? 14.923  -58.352 130.248 1   100.875 ? 907  LEU   A CA   1 ? 
ATOM   3167 C C    . LEU   A 1 213 ? 15.788  -58.809 131.419 1   93.728  ? 907  LEU   A C    1 ? 
ATOM   3168 O O    . LEU   A 1 213 ? 15.36   -58.784 132.568 1   87.889  ? 907  LEU   A O    1 ? 
ATOM   3169 C CB   . LEU   A 1 213 ? 14.297  -59.554 129.543 1   105.065 ? 907  LEU   A CB   1 ? 
ATOM   3170 C CG   . LEU   A 1 213 ? 13.409  -59.245 128.333 1   94.25   ? 907  LEU   A CG   1 ? 
ATOM   3171 C CD1  . LEU   A 1 213 ? 12.905  -60.549 127.768 1   106.032 ? 907  LEU   A CD1  1 ? 
ATOM   3172 C CD2  . LEU   A 1 213 ? 12.243  -58.34  128.665 1   95.308  ? 907  LEU   A CD2  1 ? 
ATOM   3173 H H    . LEU   A 1 213 ? 15.898  -57.965 128.477 1   93.581  ? 907  LEU   A H    1 c 
ATOM   3174 H HA   . LEU   A 1 213 ? 14.204  -57.765 130.594 1   98.31   ? 907  LEU   A HA   1 c 
ATOM   3175 H HB2  . LEU   A 1 213 ? 15.024  -60.15  129.249 1   101.553 ? 907  LEU   A HB2  1 c 
ATOM   3176 H HB3  . LEU   A 1 213 ? 13.759  -60.05  130.202 1   101.553 ? 907  LEU   A HB3  1 c 
ATOM   3177 H HG   . LEU   A 1 213 ? 13.962  -58.801 127.642 1   98.413  ? 907  LEU   A HG   1 c 
ATOM   3178 H HD11 . LEU   A 1 213 ? 13.659  -61.103 127.505 1   102.375 ? 907  LEU   A HD11 1 c 
ATOM   3179 H HD12 . LEU   A 1 213 ? 12.347  -60.373 126.992 1   102.375 ? 907  LEU   A HD12 1 c 
ATOM   3180 H HD13 . LEU   A 1 213 ? 12.382  -61.015 128.443 1   102.375 ? 907  LEU   A HD13 1 c 
ATOM   3181 H HD21 . LEU   A 1 213 ? 12.574  -57.465 128.929 1   95.054  ? 907  LEU   A HD21 1 c 
ATOM   3182 H HD22 . LEU   A 1 213 ? 11.731  -58.726 129.395 1   95.05   ? 907  LEU   A HD22 1 c 
ATOM   3183 H HD23 . LEU   A 1 213 ? 11.672  -58.247 127.884 1   95.015  ? 907  LEU   A HD23 1 c 
ATOM   3184 N N    . MET   A 1 214 ? 17.002  -59.264 131.105 1   97.145  ? 908  MET   A N    1 ? 
ATOM   3185 C CA   . MET   A 1 214 ? 17.908  -59.789 132.113 1   92.313  ? 908  MET   A CA   1 ? 
ATOM   3186 C C    . MET   A 1 214 ? 18.338  -58.678 133.057 1   85.492  ? 908  MET   A C    1 ? 
ATOM   3187 O O    . MET   A 1 214 ? 18.572  -58.93  134.227 1   95.445  ? 908  MET   A O    1 ? 
ATOM   3188 C CB   . MET   A 1 214 ? 19.149  -60.424 131.48  1   90.411  ? 908  MET   A CB   1 ? 
ATOM   3189 C CG   . MET   A 1 214 ? 18.851  -61.703 130.695 1   92.161  ? 908  MET   A CG   1 ? 
ATOM   3190 S SD   . MET   A 1 214 ? 17.583  -62.788 131.39  1   95.36   ? 908  MET   A SD   1 ? 
ATOM   3191 C CE   . MET   A 1 214 ? 17.424  -64.044 130.119 1   94.608  ? 908  MET   A CE   1 ? 
ATOM   3192 H H    . MET   A 1 214 ? 17.274  -59.255 130.232 1   95.194  ? 908  MET   A H    1 c 
ATOM   3193 H HA   . MET   A 1 214 ? 17.421  -60.47  132.641 1   91.634  ? 908  MET   A HA   1 c 
ATOM   3194 H HB2  . MET   A 1 214 ? 19.564  -59.77  130.879 1   91.229  ? 908  MET   A HB2  1 c 
ATOM   3195 H HB3  . MET   A 1 214 ? 19.794  -60.629 132.19  1   91.203  ? 908  MET   A HB3  1 c 
ATOM   3196 H HG2  . MET   A 1 214 ? 18.579  -61.459 129.791 1   92.473  ? 908  MET   A HG2  1 c 
ATOM   3197 H HG3  . MET   A 1 214 ? 19.673  -62.218 130.62  1   92.703  ? 908  MET   A HG3  1 c 
ATOM   3198 H HE1  . MET   A 1 214 ? 16.785  -64.721 130.41  1   94.78   ? 908  MET   A HE1  1 c 
ATOM   3199 H HE2  . MET   A 1 214 ? 17.108  -63.631 129.295 1   94.753  ? 908  MET   A HE2  1 c 
ATOM   3200 H HE3  . MET   A 1 214 ? 18.291  -64.461 129.963 1   94.76   ? 908  MET   A HE3  1 c 
ATOM   3201 N N    . THR   A 1 215 ? 18.427  -57.454 132.53  1   97.619  ? 909  THR   A N    1 ? 
ATOM   3202 C CA   . THR   A 1 215 ? 18.782  -56.275 133.306 1   98.688  ? 909  THR   A CA   1 ? 
ATOM   3203 C C    . THR   A 1 215 ? 17.543  -55.627 133.919 1   89.494  ? 909  THR   A C    1 ? 
ATOM   3204 O O    . THR   A 1 215 ? 17.656  -54.577 134.534 1   91.726  ? 909  THR   A O    1 ? 
ATOM   3205 C CB   . THR   A 1 215 ? 19.533  -55.282 132.422 1   95.438  ? 909  THR   A CB   1 ? 
ATOM   3206 O OG1  . THR   A 1 215 ? 18.861  -55.205 131.169 1   115.873 ? 909  THR   A OG1  1 ? 
ATOM   3207 C CG2  . THR   A 1 215 ? 20.964  -55.71  132.182 1   98.645  ? 909  THR   A CG2  1 ? 
ATOM   3208 H H    . THR   A 1 215 ? 18.27   -57.348 131.636 1   94.809  ? 909  THR   A H    1 c 
ATOM   3209 H HA   . THR   A 1 215 ? 19.381  -56.554 134.034 1   96.091  ? 909  THR   A HA   1 c 
ATOM   3210 H HB   . THR   A 1 215 ? 19.536  -54.396 132.852 1   100.423 ? 909  THR   A HB   1 c 
ATOM   3211 H HG1  . THR   A 1 215 ? 18.838  -55.965 130.776 0   117.91  ? 909  THR   A HG1  1 c 
ATOM   3212 H HG21 . THR   A 1 215 ? 21.426  -55.023 131.676 1   97.792  ? 909  THR   A HG21 1 c 
ATOM   3213 H HG22 . THR   A 1 215 ? 20.975  -56.543 131.68  1   97.706  ? 909  THR   A HG22 1 c 
ATOM   3214 H HG23 . THR   A 1 215 ? 21.412  -55.84  133.034 1   97.698  ? 909  THR   A HG23 1 c 
ATOM   3215 N N    . PHE   A 1 216 ? 16.373  -56.243 133.722 1   88.873  ? 910  PHE   A N    1 ? 
ATOM   3216 C CA   . PHE   A 1 216 ? 15.107  -55.761 134.244 1   96.061  ? 910  PHE   A CA   1 ? 
ATOM   3217 C C    . PHE   A 1 216 ? 14.744  -54.371 133.73  1   99.658  ? 910  PHE   A C    1 ? 
ATOM   3218 O O    . PHE   A 1 216 ? 14.177  -53.573 134.478 1   99.5    ? 910  PHE   A O    1 ? 
ATOM   3219 C CB   . PHE   A 1 216 ? 15.147  -55.727 135.769 1   103.073 ? 910  PHE   A CB   1 ? 
ATOM   3220 C CG   . PHE   A 1 216 ? 15.127  -57.112 136.376 1   93.131  ? 910  PHE   A CG   1 ? 
ATOM   3221 C CD1  . PHE   A 1 216 ? 13.947  -57.838 136.426 1   102.109 ? 910  PHE   A CD1  1 ? 
ATOM   3222 C CD2  . PHE   A 1 216 ? 16.277  -57.668 136.903 1   94.628  ? 910  PHE   A CD2  1 ? 
ATOM   3223 C CE1  . PHE   A 1 216 ? 13.919  -59.103 136.986 1   103.856 ? 910  PHE   A CE1  1 ? 
ATOM   3224 C CE2  . PHE   A 1 216 ? 16.243  -58.927 137.475 1   93.077  ? 910  PHE   A CE2  1 ? 
ATOM   3225 C CZ   . PHE   A 1 216 ? 15.066  -59.643 137.514 1   96.53   ? 910  PHE   A CZ   1 ? 
ATOM   3226 H H    . PHE   A 1 216 ? 16.362  -57.01  133.228 1   90.706  ? 910  PHE   A H    1 c 
ATOM   3227 H HA   . PHE   A 1 216 ? 14.395  -56.395 133.964 1   96.487  ? 910  PHE   A HA   1 c 
ATOM   3228 H HB2  . PHE   A 1 216 ? 15.958  -55.257 136.061 1   98.984  ? 910  PHE   A HB2  1 c 
ATOM   3229 H HB3  . PHE   A 1 216 ? 14.368  -55.227 136.096 1   99.247  ? 910  PHE   A HB3  1 c 
ATOM   3230 H HD1  . PHE   A 1 216 ? 13.157  -57.467 136.066 1   100.268 ? 910  PHE   A HD1  1 c 
ATOM   3231 H HD2  . PHE   A 1 216 ? 17.084  -57.18  136.886 1   94.119  ? 910  PHE   A HD2  1 c 
ATOM   3232 H HE1  . PHE   A 1 216 ? 13.112  -59.589 137.013 1   101.585 ? 910  PHE   A HE1  1 c 
ATOM   3233 H HE2  . PHE   A 1 216 ? 17.032  -59.3   137.831 1   94.374  ? 910  PHE   A HE2  1 c 
ATOM   3234 H HZ   . PHE   A 1 216 ? 15.05   -60.506 137.896 1   97.371  ? 910  PHE   A HZ   1 c 
ATOM   3235 N N    . GLY   A 1 217 ? 15.037  -54.102 132.454 1   100.038 ? 911  GLY   A N    1 ? 
ATOM   3236 C CA   . GLY   A 1 217 ? 14.604  -52.877 131.81  1   102.126 ? 911  GLY   A CA   1 ? 
ATOM   3237 C C    . GLY   A 1 217 ? 15.682  -51.8   131.756 1   97.347  ? 911  GLY   A C    1 ? 
ATOM   3238 O O    . GLY   A 1 217 ? 15.37   -50.652 131.47  1   115.62  ? 911  GLY   A O    1 ? 
ATOM   3239 H H    . GLY   A 1 217 ? 15.517  -54.708 131.966 1   100.32  ? 911  GLY   A H    1 c 
ATOM   3240 H HA2  . GLY   A 1 217 ? 14.319  -53.091 130.89  1   100.533 ? 911  GLY   A HA2  1 c 
ATOM   3241 H HA3  . GLY   A 1 217 ? 13.82   -52.526 132.286 1   100.503 ? 911  GLY   A HA3  1 c 
ATOM   3242 N N    . SER   A 1 218 ? 16.939  -52.155 132.014 1   102.021 ? 912  SER   A N    1 ? 
ATOM   3243 C CA   . SER   A 1 218 ? 18.027  -51.191 131.938 1   111.557 ? 912  SER   A CA   1 ? 
ATOM   3244 C C    . SER   A 1 218 ? 18.193  -50.719 130.498 1   106.084 ? 912  SER   A C    1 ? 
ATOM   3245 O O    . SER   A 1 218 ? 17.788  -51.411 129.573 1   104.37  ? 912  SER   A O    1 ? 
ATOM   3246 C CB   . SER   A 1 218 ? 19.319  -51.767 132.469 1   113.394 ? 912  SER   A CB   1 ? 
ATOM   3247 O OG   . SER   A 1 218 ? 19.188  -52.165 133.823 1   109.572 ? 912  SER   A OG   1 ? 
ATOM   3248 H H    . SER   A 1 218 ? 17.131  -53.019 132.24  1   102.954 ? 912  SER   A H    1 c 
ATOM   3249 H HA   . SER   A 1 218 ? 17.783  -50.408 132.494 1   108.939 ? 912  SER   A HA   1 c 
ATOM   3250 H HB2  . SER   A 1 218 ? 19.578  -52.532 131.925 1   111.87  ? 912  SER   A HB2  1 c 
ATOM   3251 H HB3  . SER   A 1 218 ? 20.023  -51.094 132.398 1   112.021 ? 912  SER   A HB3  1 c 
ATOM   3252 H HG   . SER   A 1 218 ? 19.853  -52.469 134.141 0   111.32  ? 912  SER   A HG   1 c 
ATOM   3253 N N    . LYS   A 1 219 ? 18.829  -49.556 130.32  1   113.986 ? 913  LYS   A N    1 ? 
ATOM   3254 C CA   . LYS   A 1 219 ? 19.039  -48.993 128.999 1   110.247 ? 913  LYS   A CA   1 ? 
ATOM   3255 C C    . LYS   A 1 219 ? 20.436  -49.355 128.514 1   103.348 ? 913  LYS   A C    1 ? 
ATOM   3256 O O    . LYS   A 1 219 ? 21.425  -49.08  129.189 1   118.607 ? 913  LYS   A O    1 ? 
ATOM   3257 C CB   . LYS   A 1 219 ? 18.889  -47.47  129.022 1   117.521 ? 913  LYS   A CB   1 ? 
ATOM   3258 C CG   . LYS   A 1 219 ? 17.639  -46.959 129.71  1   111.158 ? 913  LYS   A CG   1 ? 
ATOM   3259 C CD   . LYS   A 1 219 ? 17.431  -45.487 129.401 1   116.691 ? 913  LYS   A CD   1 ? 
ATOM   3260 C CE   . LYS   A 1 219 ? 16.851  -44.729 130.539 1   138.279 ? 913  LYS   A CE   1 ? 
ATOM   3261 N NZ   . LYS   A 1 219 ? 17.072  -43.285 130.399 1   143.747 ? 913  LYS   A NZ   1 ? 
ATOM   3262 H H    . LYS   A 1 219 ? 19.142  -49.1   131.048 1   111.194 ? 913  LYS   A H    1 c 
ATOM   3263 H HA   . LYS   A 1 219 ? 18.365  -49.372 128.385 1   110.775 ? 913  LYS   A HA   1 c 
ATOM   3264 H HB2  . LYS   A 1 219 ? 19.669  -47.084 129.473 1   114.323 ? 913  LYS   A HB2  1 c 
ATOM   3265 H HB3  . LYS   A 1 219 ? 18.889  -47.142 128.097 1   114.397 ? 913  LYS   A HB3  1 c 
ATOM   3266 H HG2  . LYS   A 1 219 ? 16.864  -47.475 129.396 1   113.878 ? 913  LYS   A HG2  1 c 
ATOM   3267 H HG3  . LYS   A 1 219 ? 17.73   -47.087 130.679 1   114.091 ? 913  LYS   A HG3  1 c 
ATOM   3268 H HD2  . LYS   A 1 219 ? 18.294  -45.085 129.158 1   120.156 ? 913  LYS   A HD2  1 c 
ATOM   3269 H HD3  . LYS   A 1 219 ? 16.834  -45.405 128.626 1   120.089 ? 913  LYS   A HD3  1 c 
ATOM   3270 H HE2  . LYS   A 1 219 ? 15.893  -44.899 130.587 1   134.118 ? 913  LYS   A HE2  1 c 
ATOM   3271 H HE3  . LYS   A 1 219 ? 17.254  -45.027 131.374 1   133.893 ? 913  LYS   A HE3  1 c 
ATOM   3272 H HZ1  . LYS   A 1 219 ? 16.718  -42.996 129.616 1   142.002 ? 913  LYS   A HZ1  1 c 
ATOM   3273 H HZ2  . LYS   A 1 219 ? 17.96   -43.108 130.409 1   141.877 ? 913  LYS   A HZ2  1 c 
ATOM   3274 H HZ3  . LYS   A 1 219 ? 16.674  -42.847 131.085 1   142.002 ? 913  LYS   A HZ3  1 c 
ATOM   3275 N N    . PRO   A 1 220 ? 20.557  -49.961 127.317 1   106.91  ? 914  PRO   A N    1 ? 
ATOM   3276 C CA   . PRO   A 1 220 ? 21.847  -50.376 126.777 1   111.993 ? 914  PRO   A CA   1 ? 
ATOM   3277 C C    . PRO   A 1 220 ? 22.731  -49.201 126.386 1   106.56  ? 914  PRO   A C    1 ? 
ATOM   3278 O O    . PRO   A 1 220 ? 22.238  -48.24  125.821 1   108.968 ? 914  PRO   A O    1 ? 
ATOM   3279 C CB   . PRO   A 1 220 ? 21.494  -51.194 125.538 1   101.017 ? 914  PRO   A CB   1 ? 
ATOM   3280 C CG   . PRO   A 1 220 ? 20.162  -50.624 125.135 1   107.446 ? 914  PRO   A CG   1 ? 
ATOM   3281 C CD   . PRO   A 1 220 ? 19.451  -50.26  126.409 1   106.049 ? 914  PRO   A CD   1 ? 
ATOM   3282 H HA   . PRO   A 1 220 ? 22.311  -50.941 127.43  1   108.08  ? 914  PRO   A HA   1 c 
ATOM   3283 H HB2  . PRO   A 1 220 ? 22.158  -51.072 124.832 1   104.859 ? 914  PRO   A HB2  1 c 
ATOM   3284 H HB3  . PRO   A 1 220 ? 21.419  -52.144 125.753 1   104.843 ? 914  PRO   A HB3  1 c 
ATOM   3285 H HG2  . PRO   A 1 220 ? 20.283  -49.831 124.575 1   105.631 ? 914  PRO   A HG2  1 c 
ATOM   3286 H HG3  . PRO   A 1 220 ? 19.643  -51.283 124.633 1   105.631 ? 914  PRO   A HG3  1 c 
ATOM   3287 H HD2  . PRO   A 1 220 ? 18.88   -49.477 126.283 1   106.617 ? 914  PRO   A HD2  1 c 
ATOM   3288 H HD3  . PRO   A 1 220 ? 18.914  -51.004 126.745 1   106.599 ? 914  PRO   A HD3  1 c 
ATOM   3289 N N    . TYR   A 1 221 ? 24.028  -49.304 126.699 1   117.763 ? 915  TYR   A N    1 ? 
ATOM   3290 C CA   . TYR   A 1 221 ? 25.001  -48.271 126.388 1   111.849 ? 915  TYR   A CA   1 ? 
ATOM   3291 C C    . TYR   A 1 221 ? 24.559  -46.927 126.951 1   119.417 ? 915  TYR   A C    1 ? 
ATOM   3292 O O    . TYR   A 1 221 ? 24.674  -45.914 126.276 1   123.313 ? 915  TYR   A O    1 ? 
ATOM   3293 C CB   . TYR   A 1 221 ? 25.141  -48.144 124.877 1   102.002 ? 915  TYR   A CB   1 ? 
ATOM   3294 C CG   . TYR   A 1 221 ? 25.33   -49.46  124.149 1   99.765  ? 915  TYR   A CG   1 ? 
ATOM   3295 C CD1  . TYR   A 1 221 ? 26.529  -50.145 124.247 1   102.47  ? 915  TYR   A CD1  1 ? 
ATOM   3296 C CD2  . TYR   A 1 221 ? 24.351  -49.973 123.303 1   107.816 ? 915  TYR   A CD2  1 ? 
ATOM   3297 C CE1  . TYR   A 1 221 ? 26.748  -51.323 123.554 1   106.605 ? 915  TYR   A CE1  1 ? 
ATOM   3298 C CE2  . TYR   A 1 221 ? 24.557  -51.153 122.605 1   107.254 ? 915  TYR   A CE2  1 ? 
ATOM   3299 C CZ   . TYR   A 1 221 ? 25.763  -51.823 122.725 1   105.613 ? 915  TYR   A CZ   1 ? 
ATOM   3300 O OH   . TYR   A 1 221 ? 26.012  -52.976 122.05  1   107.112 ? 915  TYR   A OH   1 ? 
ATOM   3301 H H    . TYR   A 1 221 ? 24.319  -50.057 127.127 1   113.595 ? 915  TYR   A H    1 c 
ATOM   3302 H HA   . TYR   A 1 221 ? 25.879  -48.521 126.78  1   112.417 ? 915  TYR   A HA   1 c 
ATOM   3303 H HB2  . TYR   A 1 221 ? 24.338  -47.703 124.524 1   104.11  ? 915  TYR   A HB2  1 c 
ATOM   3304 H HB3  . TYR   A 1 221 ? 25.91   -47.563 124.684 1   103.826 ? 915  TYR   A HB3  1 c 
ATOM   3305 H HD1  . TYR   A 1 221 ? 27.214  -49.801 124.798 1   102.862 ? 915  TYR   A HD1  1 c 
ATOM   3306 H HD2  . TYR   A 1 221 ? 23.529  -49.522 123.215 1   106.056 ? 915  TYR   A HD2  1 c 
ATOM   3307 H HE1  . TYR   A 1 221 ? 27.57   -51.775 123.635 1   105.384 ? 915  TYR   A HE1  1 c 
ATOM   3308 H HE2  . TYR   A 1 221 ? 23.882  -51.495 122.044 1   106.993 ? 915  TYR   A HE2  1 c 
ATOM   3309 H HH   . TYR   A 1 221 ? 26.763  -53.268 122.208 0   106.67  ? 915  TYR   A HH   1 c 
ATOM   3310 N N    . ASP   A 1 222 ? 24.031  -46.932 128.179 1   130.875 ? 916  ASP   A N    1 ? 
ATOM   3311 C CA   . ASP   A 1 222 ? 23.435  -45.739 128.754 1   131.755 ? 916  ASP   A CA   1 ? 
ATOM   3312 C C    . ASP   A 1 222 ? 24.461  -44.61  128.752 1   133.102 ? 916  ASP   A C    1 ? 
ATOM   3313 O O    . ASP   A 1 222 ? 25.632  -44.859 129.017 1   117.986 ? 916  ASP   A O    1 ? 
ATOM   3314 C CB   . ASP   A 1 222 ? 22.911  -45.984 130.158 1   130.732 ? 916  ASP   A CB   1 ? 
ATOM   3315 C CG   . ASP   A 1 222 ? 21.735  -45.101 130.532 1   130.433 ? 916  ASP   A CG   1 ? 
ATOM   3316 O OD1  . ASP   A 1 222 ? 21.329  -44.285 129.69  1   130.635 ? 916  ASP   A OD1  1 ? 
ATOM   3317 O OD2  . ASP   A 1 222 ? 21.223  -45.259 131.651 1   138.613 ? 916  ASP   A OD2  1 ? 
ATOM   3318 H H    . ASP   A 1 222 ? 24.053  -47.699 128.675 1   128.087 ? 916  ASP   A H    1 c 
ATOM   3319 H HA   . ASP   A 1 222 ? 22.679  -45.476 128.182 1   131.72  ? 916  ASP   A HA   1 c 
ATOM   3320 H HB2  . ASP   A 1 222 ? 22.626  -46.918 130.238 1   130.811 ? 916  ASP   A HB2  1 c 
ATOM   3321 H HB3  . ASP   A 1 222 ? 23.631  -45.83  130.805 1   130.891 ? 916  ASP   A HB3  1 c 
ATOM   3322 N N    . GLY   A 1 223 ? 23.998  -43.393 128.431 1   139.725 ? 917  GLY   A N    1 ? 
ATOM   3323 C CA   . GLY   A 1 223 ? 24.85   -42.225 128.261 1   143.481 ? 917  GLY   A CA   1 ? 
ATOM   3324 C C    . GLY   A 1 223 ? 25.967  -42.435 127.233 1   144.605 ? 917  GLY   A C    1 ? 
ATOM   3325 O O    . GLY   A 1 223 ? 27.104  -42.054 127.485 1   144.271 ? 917  GLY   A O    1 ? 
ATOM   3326 H H    . GLY   A 1 223 ? 23.098  -43.287 128.314 1   138.837 ? 917  GLY   A H    1 c 
ATOM   3327 H HA2  . GLY   A 1 223 ? 24.29   -41.463 127.98  1   142.822 ? 917  GLY   A HA2  1 c 
ATOM   3328 H HA3  . GLY   A 1 223 ? 25.25   -41.996 129.132 1   142.822 ? 917  GLY   A HA3  1 c 
ATOM   3329 N N    . ILE   A 1 224 ? 25.655  -43.03  126.071 1   146.357 ? 918  ILE   A N    1 ? 
ATOM   3330 C CA   . ILE   A 1 224 ? 26.59   -43.095 124.955 1   138.503 ? 918  ILE   A CA   1 ? 
ATOM   3331 C C    . ILE   A 1 224 ? 25.943  -42.501 123.702 1   146.764 ? 918  ILE   A C    1 ? 
ATOM   3332 O O    . ILE   A 1 224 ? 24.824  -42.846 123.356 1   147.197 ? 918  ILE   A O    1 ? 
ATOM   3333 C CB   . ILE   A 1 224 ? 27.083  -44.53  124.688 1   137.284 ? 918  ILE   A CB   1 ? 
ATOM   3334 C CG1  . ILE   A 1 224 ? 28.44   -44.776 125.382 1   124.426 ? 918  ILE   A CG1  1 ? 
ATOM   3335 C CG2  . ILE   A 1 224 ? 27.122  -44.816 123.178 1   150.567 ? 918  ILE   A CG2  1 ? 
ATOM   3336 C CD1  . ILE   A 1 224 ? 29.476  -45.486 124.538 1   135.292 ? 918  ILE   A CD1  1 ? 
ATOM   3337 H H    . ILE   A 1 224 ? 24.828  -43.406 125.972 1   144.103 ? 918  ILE   A H    1 c 
ATOM   3338 H HA   . ILE   A 1 224 ? 27.365  -42.55  125.181 1   141.361 ? 918  ILE   A HA   1 c 
ATOM   3339 H HB   . ILE   A 1 224 ? 26.438  -45.141 125.087 1   137.306 ? 918  ILE   A HB   1 c 
ATOM   3340 H HG12 . ILE   A 1 224 ? 28.81   -43.916 125.666 1   129.837 ? 918  ILE   A HG12 1 c 
ATOM   3341 H HG13 . ILE   A 1 224 ? 28.281  -45.308 126.189 1   129.723 ? 918  ILE   A HG13 1 c 
ATOM   3342 H HG21 . ILE   A 1 224 ? 27.427  -45.726 123.028 1   145.869 ? 918  ILE   A HG21 1 c 
ATOM   3343 H HG22 . ILE   A 1 224 ? 27.733  -44.198 122.744 1   146.233 ? 918  ILE   A HG22 1 c 
ATOM   3344 H HG23 . ILE   A 1 224 ? 26.234  -44.714 122.8   1   146.214 ? 918  ILE   A HG23 1 c 
ATOM   3345 H HD11 . ILE   A 1 224 ? 29.144  -46.367 124.283 1   132.082 ? 918  ILE   A HD11 1 c 
ATOM   3346 H HD12 . ILE   A 1 224 ? 30.295  -45.59  125.059 1   132.015 ? 918  ILE   A HD12 1 c 
ATOM   3347 H HD13 . ILE   A 1 224 ? 29.671  -44.967 123.735 1   132.102 ? 918  ILE   A HD13 1 c 
ATOM   3348 N N    . PRO   A 1 225 ? 26.622  -41.583 122.982 1   154.599 ? 919  PRO   A N    1 ? 
ATOM   3349 C CA   . PRO   A 1 225 ? 26.251  -41.235 121.615 1   146.931 ? 919  PRO   A CA   1 ? 
ATOM   3350 C C    . PRO   A 1 225 ? 26.229  -42.397 120.619 1   142.458 ? 919  PRO   A C    1 ? 
ATOM   3351 O O    . PRO   A 1 225 ? 27.151  -43.218 120.555 1   150.147 ? 919  PRO   A O    1 ? 
ATOM   3352 C CB   . PRO   A 1 225 ? 27.312  -40.218 121.218 1   152.509 ? 919  PRO   A CB   1 ? 
ATOM   3353 C CG   . PRO   A 1 225 ? 27.689  -39.593 122.55  1   147.779 ? 919  PRO   A CG   1 ? 
ATOM   3354 C CD   . PRO   A 1 225 ? 27.707  -40.74  123.5   1   158.821 ? 919  PRO   A CD   1 ? 
ATOM   3355 H HA   . PRO   A 1 225 ? 25.375  -40.798 121.623 1   148.371 ? 919  PRO   A HA   1 c 
ATOM   3356 H HB2  . PRO   A 1 225 ? 28.081  -40.654 120.804 1   150.246 ? 919  PRO   A HB2  1 c 
ATOM   3357 H HB3  . PRO   A 1 225 ? 26.947  -39.549 120.606 1   150.181 ? 919  PRO   A HB3  1 c 
ATOM   3358 H HG2  . PRO   A 1 225 ? 28.57   -39.17  122.501 1   151.319 ? 919  PRO   A HG2  1 c 
ATOM   3359 H HG3  . PRO   A 1 225 ? 27.029  -38.926 122.824 1   151.319 ? 919  PRO   A HG3  1 c 
ATOM   3360 H HD2  . PRO   A 1 225 ? 28.561  -41.215 123.475 1   155.235 ? 919  PRO   A HD2  1 c 
ATOM   3361 H HD3  . PRO   A 1 225 ? 27.521  -40.449 124.413 1   155.083 ? 919  PRO   A HD3  1 c 
ATOM   3362 N N    . ALA   A 1 226 ? 25.154  -42.41  119.819 1   131.928 ? 920  ALA   A N    1 ? 
ATOM   3363 C CA   . ALA   A 1 226 ? 24.944  -43.373 118.754 1   141.785 ? 920  ALA   A CA   1 ? 
ATOM   3364 C C    . ALA   A 1 226 ? 26.089  -43.303 117.742 1   139.096 ? 920  ALA   A C    1 ? 
ATOM   3365 O O    . ALA   A 1 226 ? 26.463  -44.309 117.139 1   146.936 ? 920  ALA   A O    1 ? 
ATOM   3366 C CB   . ALA   A 1 226 ? 23.613  -43.091 118.106 1   146.817 ? 920  ALA   A CB   1 ? 
ATOM   3367 H H    . ALA   A 1 226 ? 24.511  -41.773 119.951 1   136.884 ? 920  ALA   A H    1 c 
ATOM   3368 H HA   . ALA   A 1 226 ? 24.928  -44.279 119.15  1   139.912 ? 920  ALA   A HA   1 c 
ATOM   3369 H HB1  . ALA   A 1 226 ? 22.903  -43.212 118.757 1   145.313 ? 920  ALA   A HB1  1 c 
ATOM   3370 H HB2  . ALA   A 1 226 ? 23.596  -42.174 117.782 1   145.247 ? 920  ALA   A HB2  1 c 
ATOM   3371 H HB3  . ALA   A 1 226 ? 23.478  -43.695 117.359 1   145.283 ? 920  ALA   A HB3  1 c 
ATOM   3372 N N    . SER   A 1 227 ? 26.617  -42.088 117.557 1   143.221 ? 921  SER   A N    1 ? 
ATOM   3373 C CA   . SER   A 1 227 ? 27.804  -41.833 116.756 1   141.604 ? 921  SER   A CA   1 ? 
ATOM   3374 C C    . SER   A 1 227 ? 28.982  -42.697 117.218 1   148.326 ? 921  SER   A C    1 ? 
ATOM   3375 O O    . SER   A 1 227 ? 29.654  -43.29  116.378 1   127.816 ? 921  SER   A O    1 ? 
ATOM   3376 C CB   . SER   A 1 227 ? 28.122  -40.363 116.799 1   141.12  ? 921  SER   A CB   1 ? 
ATOM   3377 O OG   . SER   A 1 227 ? 27.474  -39.761 117.913 1   131.84  ? 921  SER   A OG   1 ? 
ATOM   3378 H H    . SER   A 1 227 ? 26.201  -41.371 117.942 1   141.783 ? 921  SER   A H    1 c 
ATOM   3379 H HA   . SER   A 1 227 ? 27.596  -42.076 115.818 1   142.935 ? 921  SER   A HA   1 c 
ATOM   3380 H HB2  . SER   A 1 227 ? 29.088  -40.238 116.874 1   139.013 ? 921  SER   A HB2  1 c 
ATOM   3381 H HB3  . SER   A 1 227 ? 27.818  -39.94  115.974 1   138.971 ? 921  SER   A HB3  1 c 
ATOM   3382 H HG   . SER   A 1 227 ? 27.692  -38.934 117.92  0   132.73  ? 921  SER   A HG   1 c 
ATOM   3383 N N    . GLU   A 1 228 ? 29.21   -42.765 118.546 1   165.68  ? 922  GLU   A N    1 ? 
ATOM   3384 C CA   . GLU   A 1 228 ? 30.208  -43.64  119.171 1   165.342 ? 922  GLU   A CA   1 ? 
ATOM   3385 C C    . GLU   A 1 228 ? 30.047  -45.109 118.761 1   158.025 ? 922  GLU   A C    1 ? 
ATOM   3386 O O    . GLU   A 1 228 ? 31.034  -45.782 118.428 1   149.038 ? 922  GLU   A O    1 ? 
ATOM   3387 C CB   . GLU   A 1 228 ? 30.116  -43.563 120.702 1   162.343 ? 922  GLU   A CB   1 ? 
ATOM   3388 C CG   . GLU   A 1 228 ? 31.094  -42.588 121.347 1   167.053 ? 922  GLU   A CG   1 ? 
ATOM   3389 C CD   . GLU   A 1 228 ? 31.471  -41.462 120.411 1   173.65  ? 922  GLU   A CD   1 ? 
ATOM   3390 O OE1  . GLU   A 1 228 ? 32.676  -41.305 120.125 1   188.681 ? 922  GLU   A OE1  1 ? 
ATOM   3391 O OE2  . GLU   A 1 228 ? 30.542  -40.788 119.926 1   175.338 ? 922  GLU   A OE2  1 ? 
ATOM   3392 H H    . GLU   A 1 228 ? 28.717  -42.223 119.092 1   160.957 ? 922  GLU   A H    1 c 
ATOM   3393 H HA   . GLU   A 1 228 ? 31.106  -43.339 118.884 1   163.573 ? 922  GLU   A HA   1 c 
ATOM   3394 H HB2  . GLU   A 1 228 ? 29.21   -43.301 120.955 1   163.947 ? 922  GLU   A HB2  1 c 
ATOM   3395 H HB3  . GLU   A 1 228 ? 30.28   -44.455 121.074 1   164.023 ? 922  GLU   A HB3  1 c 
ATOM   3396 H HG2  . GLU   A 1 228 ? 30.689  -42.207 122.156 1   167.485 ? 922  GLU   A HG2  1 c 
ATOM   3397 H HG3  . GLU   A 1 228 ? 31.908  -43.069 121.61  1   167.585 ? 922  GLU   A HG3  1 c 
ATOM   3398 N N    . ILE   A 1 229 ? 28.785  -45.572 118.757 1   141.211 ? 923  ILE   A N    1 ? 
ATOM   3399 C CA   . ILE   A 1 229 ? 28.42   -46.986 118.841 1   127.817 ? 923  ILE   A CA   1 ? 
ATOM   3400 C C    . ILE   A 1 229 ? 29.142  -47.851 117.8   1   126.548 ? 923  ILE   A C    1 ? 
ATOM   3401 O O    . ILE   A 1 229 ? 29.589  -48.943 118.145 1   151.687 ? 923  ILE   A O    1 ? 
ATOM   3402 C CB   . ILE   A 1 229 ? 26.89   -47.166 118.736 1   131.311 ? 923  ILE   A CB   1 ? 
ATOM   3403 C CG1  . ILE   A 1 229 ? 26.137  -46.413 119.854 1   125.3   ? 923  ILE   A CG1  1 ? 
ATOM   3404 C CG2  . ILE   A 1 229 ? 26.502  -48.65  118.681 1   129.604 ? 923  ILE   A CG2  1 ? 
ATOM   3405 C CD1  . ILE   A 1 229 ? 26.02   -47.179 121.154 1   124.652 ? 923  ILE   A CD1  1 ? 
ATOM   3406 H H    . ILE   A 1 229 ? 28.109  -44.962 118.686 1   141.803 ? 923  ILE   A H    1 c 
ATOM   3407 H HA   . ILE   A 1 229 ? 28.691  -47.303 119.725 1   130.837 ? 923  ILE   A HA   1 c 
ATOM   3408 H HB   . ILE   A 1 229 ? 26.614  -46.767 117.888 1   129.293 ? 923  ILE   A HB   1 c 
ATOM   3409 H HG12 . ILE   A 1 229 ? 26.593  -45.567 120.031 1   126.908 ? 923  ILE   A HG12 1 c 
ATOM   3410 H HG13 . ILE   A 1 229 ? 25.235  -46.207 119.535 1   126.673 ? 923  ILE   A HG13 1 c 
ATOM   3411 H HG21 . ILE   A 1 229 ? 25.548  -48.743 118.846 1   130.025 ? 923  ILE   A HG21 1 c 
ATOM   3412 H HG22 . ILE   A 1 229 ? 26.996  -49.142 119.358 1   130.053 ? 923  ILE   A HG22 1 c 
ATOM   3413 H HG23 . ILE   A 1 229 ? 26.711  -49.011 117.803 1   130.059 ? 923  ILE   A HG23 1 c 
ATOM   3414 H HD11 . ILE   A 1 229 ? 25.5    -47.993 121.016 1   125.031 ? 923  ILE   A HD11 1 c 
ATOM   3415 H HD12 . ILE   A 1 229 ? 25.573  -46.623 121.818 1   125.289 ? 923  ILE   A HD12 1 c 
ATOM   3416 H HD13 . ILE   A 1 229 ? 26.91   -47.416 121.475 1   125.088 ? 923  ILE   A HD13 1 c 
ATOM   3417 N N    . SER   A 1 230 ? 29.212  -47.423 116.53  1   123.434 ? 924  SER   A N    1 ? 
ATOM   3418 C CA   . SER   A 1 230 ? 29.795  -48.255 115.477 1   134.217 ? 924  SER   A CA   1 ? 
ATOM   3419 C C    . SER   A 1 230 ? 31.257  -48.593 115.768 1   147.021 ? 924  SER   A C    1 ? 
ATOM   3420 O O    . SER   A 1 230 ? 31.687  -49.728 115.548 1   130.312 ? 924  SER   A O    1 ? 
ATOM   3421 C CB   . SER   A 1 230 ? 29.653  -47.607 114.129 1   130.052 ? 924  SER   A CB   1 ? 
ATOM   3422 O OG   . SER   A 1 230 ? 29.261  -46.255 114.288 1   138.838 ? 924  SER   A OG   1 ? 
ATOM   3423 H H    . SER   A 1 230 ? 28.887  -46.597 116.313 1   126.627 ? 924  SER   A H    1 c 
ATOM   3424 H HA   . SER   A 1 230 ? 29.289  -49.107 115.457 1   133.566 ? 924  SER   A HA   1 c 
ATOM   3425 H HB2  . SER   A 1 230 ? 30.503  -47.649 113.652 1   133.119 ? 924  SER   A HB2  1 c 
ATOM   3426 H HB3  . SER   A 1 230 ? 28.98   -48.084 113.607 1   133.053 ? 924  SER   A HB3  1 c 
ATOM   3427 H HG   . SER   A 1 230 ? 29.191  -45.881 113.509 0   140.24  ? 924  SER   A HG   1 c 
ATOM   3428 N N    . SER   A 1 231 ? 31.999  -47.59  116.261 1   157.037 ? 925  SER   A N    1 ? 
ATOM   3429 C CA   . SER   A 1 231 ? 33.408  -47.722 116.609 1   152.189 ? 925  SER   A CA   1 ? 
ATOM   3430 C C    . SER   A 1 231 ? 33.591  -48.74  117.732 1   143.635 ? 925  SER   A C    1 ? 
ATOM   3431 O O    . SER   A 1 231 ? 34.491  -49.579 117.679 1   143.461 ? 925  SER   A O    1 ? 
ATOM   3432 C CB   . SER   A 1 231 ? 33.953  -46.395 117.035 1   140.446 ? 925  SER   A CB   1 ? 
ATOM   3433 O OG   . SER   A 1 231 ? 32.946  -45.409 116.87  1   145.83  ? 925  SER   A OG   1 ? 
ATOM   3434 H H    . SER   A 1 231 ? 31.602  -46.775 116.38  1   153.027 ? 925  SER   A H    1 c 
ATOM   3435 H HA   . SER   A 1 231 ? 33.905  -48.034 115.811 1   149.26  ? 925  SER   A HA   1 c 
ATOM   3436 H HB2  . SER   A 1 231 ? 34.228  -46.433 117.971 1   144.312 ? 925  SER   A HB2  1 c 
ATOM   3437 H HB3  . SER   A 1 231 ? 34.73   -46.168 116.489 1   144.319 ? 925  SER   A HB3  1 c 
ATOM   3438 H HG   . SER   A 1 231 ? 33.248  -44.668 117.09  0   147.03  ? 925  SER   A HG   1 c 
ATOM   3439 N N    . ILE   A 1 232 ? 32.727  -48.63  118.748 1   123.44  ? 926  ILE   A N    1 ? 
ATOM   3440 C CA   . ILE   A 1 232 ? 32.76   -49.499 119.913 1   112.886 ? 926  ILE   A CA   1 ? 
ATOM   3441 C C    . ILE   A 1 232 ? 32.629  -50.948 119.456 1   104.381 ? 926  ILE   A C    1 ? 
ATOM   3442 O O    . ILE   A 1 232 ? 33.414  -51.815 119.842 1   113.506 ? 926  ILE   A O    1 ? 
ATOM   3443 C CB   . ILE   A 1 232 ? 31.641  -49.114 120.897 1   113.746 ? 926  ILE   A CB   1 ? 
ATOM   3444 C CG1  . ILE   A 1 232 ? 31.634  -47.6   121.134 1   125.167 ? 926  ILE   A CG1  1 ? 
ATOM   3445 C CG2  . ILE   A 1 232 ? 31.733  -49.925 122.192 1   132.129 ? 926  ILE   A CG2  1 ? 
ATOM   3446 C CD1  . ILE   A 1 232 ? 31.372  -47.168 122.567 1   114.691 ? 926  ILE   A CD1  1 ? 
ATOM   3447 H H    . ILE   A 1 232 ? 32.079  -47.987 118.703 1   125.602 ? 926  ILE   A H    1 c 
ATOM   3448 H HA   . ILE   A 1 232 ? 33.622  -49.387 120.36  1   113.379 ? 926  ILE   A HA   1 c 
ATOM   3449 H HB   . ILE   A 1 232 ? 30.792  -49.343 120.471 1   118.989 ? 926  ILE   A HB   1 c 
ATOM   3450 H HG12 . ILE   A 1 232 ? 32.498  -47.235 120.856 1   120.115 ? 926  ILE   A HG12 1 c 
ATOM   3451 H HG13 . ILE   A 1 232 ? 30.946  -47.202 120.562 1   120.365 ? 926  ILE   A HG13 1 c 
ATOM   3452 H HG21 . ILE   A 1 232 ? 31.013  -49.671 122.793 1   126.258 ? 926  ILE   A HG21 1 c 
ATOM   3453 H HG22 . ILE   A 1 232 ? 32.588  -49.76  122.623 1   126.297 ? 926  ILE   A HG22 1 c 
ATOM   3454 H HG23 . ILE   A 1 232 ? 31.653  -50.869 121.983 1   126.275 ? 926  ILE   A HG23 1 c 
ATOM   3455 H HD11 . ILE   A 1 232 ? 30.507  -47.511 122.861 1   118.063 ? 926  ILE   A HD11 1 c 
ATOM   3456 H HD12 . ILE   A 1 232 ? 31.363  -46.193 122.607 1   117.969 ? 926  ILE   A HD12 1 c 
ATOM   3457 H HD13 . ILE   A 1 232 ? 32.073  -47.507 123.155 1   117.92  ? 926  ILE   A HD13 1 c 
ATOM   3458 N N    . LEU   A 1 233 ? 31.629  -51.193 118.616 1   103.382 ? 927  LEU   A N    1 ? 
ATOM   3459 C CA   . LEU   A 1 233 ? 31.387  -52.531 118.116 1   120.494 ? 927  LEU   A CA   1 ? 
ATOM   3460 C C    . LEU   A 1 233 ? 32.547  -52.941 117.223 1   127.427 ? 927  LEU   A C    1 ? 
ATOM   3461 O O    . LEU   A 1 233 ? 32.983  -54.093 117.264 1   134.021 ? 927  LEU   A O    1 ? 
ATOM   3462 C CB   . LEU   A 1 233 ? 30.056  -52.566 117.371 1   131.077 ? 927  LEU   A CB   1 ? 
ATOM   3463 C CG   . LEU   A 1 233 ? 28.834  -52.155 118.197 1   127.188 ? 927  LEU   A CG   1 ? 
ATOM   3464 C CD1  . LEU   A 1 233 ? 27.599  -52.785 117.603 1   127.85  ? 927  LEU   A CD1  1 ? 
ATOM   3465 C CD2  . LEU   A 1 233 ? 28.991  -52.488 119.676 1   119.397 ? 927  LEU   A CD2  1 ? 
ATOM   3466 H H    . LEU   A 1 233 ? 31.081  -50.512 118.348 1   107.649 ? 927  LEU   A H    1 c 
ATOM   3467 H HA   . LEU   A 1 233 ? 31.35   -53.153 118.886 1   119.805 ? 927  LEU   A HA   1 c 
ATOM   3468 H HB2  . LEU   A 1 233 ? 30.126  -51.958 116.6   1   127.648 ? 927  LEU   A HB2  1 c 
ATOM   3469 H HB3  . LEU   A 1 233 ? 29.916  -53.48  117.031 1   127.685 ? 927  LEU   A HB3  1 c 
ATOM   3470 H HG   . LEU   A 1 233 ? 28.732  -51.173 118.121 1   126.667 ? 927  LEU   A HG   1 c 
ATOM   3471 H HD11 . LEU   A 1 233 ? 27.389  -52.354 116.757 1   127.309 ? 927  LEU   A HD11 1 c 
ATOM   3472 H HD12 . LEU   A 1 233 ? 26.851  -52.677 118.214 1   127.035 ? 927  LEU   A HD12 1 c 
ATOM   3473 H HD13 . LEU   A 1 233 ? 27.762  -53.726 117.452 1   126.489 ? 927  LEU   A HD13 1 c 
ATOM   3474 H HD21 . LEU   A 1 233 ? 29.651  -51.898 120.077 1   121.518 ? 927  LEU   A HD21 1 c 
ATOM   3475 H HD22 . LEU   A 1 233 ? 29.28   -53.411 119.774 1   121.599 ? 927  LEU   A HD22 1 c 
ATOM   3476 H HD23 . LEU   A 1 233 ? 28.139  -52.369 120.127 1   121.644 ? 927  LEU   A HD23 1 c 
ATOM   3477 N N    . GLU   A 1 234 ? 33.028  -51.98  116.425 1   142.812 ? 928  GLU   A N    1 ? 
ATOM   3478 C CA   . GLU   A 1 234 ? 34.196  -52.205 115.594 1   145.948 ? 928  GLU   A CA   1 ? 
ATOM   3479 C C    . GLU   A 1 234 ? 35.372  -52.52  116.512 1   139.795 ? 928  GLU   A C    1 ? 
ATOM   3480 O O    . GLU   A 1 234 ? 36.148  -53.421 116.213 1   140.346 ? 928  GLU   A O    1 ? 
ATOM   3481 C CB   . GLU   A 1 234 ? 34.46   -50.993 114.706 1   144.157 ? 928  GLU   A CB   1 ? 
ATOM   3482 C CG   . GLU   A 1 234 ? 34.979  -51.379 113.325 1   140.574 ? 928  GLU   A CG   1 ? 
ATOM   3483 C CD   . GLU   A 1 234 ? 34.109  -50.805 112.227 1   144.136 ? 928  GLU   A CD   1 ? 
ATOM   3484 O OE1  . GLU   A 1 234 ? 33.814  -51.56  111.274 1   140.557 ? 928  GLU   A OE1  1 ? 
ATOM   3485 O OE2  . GLU   A 1 234 ? 33.701  -49.624 112.34  1   144.929 ? 928  GLU   A OE2  1 ? 
ATOM   3486 H H    . GLU   A 1 234 ? 32.612  -51.167 116.395 1   139.299 ? 928  GLU   A H    1 c 
ATOM   3487 H HA   . GLU   A 1 234 ? 34.02   -52.996 115.024 1   143.697 ? 928  GLU   A HA   1 c 
ATOM   3488 H HB2  . GLU   A 1 234 ? 33.633  -50.483 114.61  1   143.606 ? 928  GLU   A HB2  1 c 
ATOM   3489 H HB3  . GLU   A 1 234 ? 35.118  -50.414 115.145 1   143.689 ? 928  GLU   A HB3  1 c 
ATOM   3490 H HG2  . GLU   A 1 234 ? 35.894  -51.043 113.215 1   142.194 ? 928  GLU   A HG2  1 c 
ATOM   3491 H HG3  . GLU   A 1 234 ? 34.998  -52.356 113.239 1   142.212 ? 928  GLU   A HG3  1 c 
ATOM   3492 N N    . LYS   A 1 235 ? 35.439  -51.803 117.648 1   132.83  ? 929  LYS   A N    1 ? 
ATOM   3493 C CA   . LYS   A 1 235 ? 36.43   -52.027 118.696 1   128.38  ? 929  LYS   A CA   1 ? 
ATOM   3494 C C    . LYS   A 1 235 ? 36.308  -53.446 119.27  1   126.538 ? 929  LYS   A C    1 ? 
ATOM   3495 O O    . LYS   A 1 235 ? 37.298  -54.02  119.715 1   125.437 ? 929  LYS   A O    1 ? 
ATOM   3496 C CB   . LYS   A 1 235 ? 36.315  -50.95  119.785 1   113.611 ? 929  LYS   A CB   1 ? 
ATOM   3497 H H    . LYS   A 1 235 ? 34.837  -51.127 117.767 1   133.404 ? 929  LYS   A H    1 c 
ATOM   3498 H HA   . LYS   A 1 235 ? 37.328  -51.942 118.285 1   126.035 ? 929  LYS   A HA   1 c 
ATOM   3499 H HB2  . LYS   A 1 235 ? 37.147  -50.676 120.082 0   117.11  ? 929  LYS   A HB2  1 c 
ATOM   3500 H HB3  . LYS   A 1 235 ? 35.297  -50.802 119.952 0   117.11  ? 929  LYS   A HB3  1 c 
ATOM   3501 N N    . GLY   A 1 236 ? 35.101  -54.024 119.231 1   140.006 ? 930  GLY   A N    1 ? 
ATOM   3502 C CA   . GLY   A 1 236 ? 34.854  -55.369 119.739 1   136.156 ? 930  GLY   A CA   1 ? 
ATOM   3503 C C    . GLY   A 1 236 ? 34.259  -55.358 121.154 1   128.106 ? 930  GLY   A C    1 ? 
ATOM   3504 O O    . GLY   A 1 236 ? 34.113  -56.413 121.78  1   112.312 ? 930  GLY   A O    1 ? 
ATOM   3505 H H    . GLY   A 1 236 ? 34.395  -53.554 118.892 1   135.493 ? 930  GLY   A H    1 c 
ATOM   3506 H HA2  . GLY   A 1 236 ? 34.233  -55.828 119.13  1   134.992 ? 930  GLY   A HA2  1 c 
ATOM   3507 H HA3  . GLY   A 1 236 ? 35.7    -55.875 119.743 1   135.066 ? 930  GLY   A HA3  1 c 
ATOM   3508 N N    . GLU   A 1 237 ? 33.926  -54.158 121.655 1   107.544 ? 931  GLU   A N    1 ? 
ATOM   3509 C CA   . GLU   A 1 237 ? 33.215  -54.014 122.915 1   101.898 ? 931  GLU   A CA   1 ? 
ATOM   3510 C C    . GLU   A 1 237 ? 31.748  -54.407 122.744 1   110.493 ? 931  GLU   A C    1 ? 
ATOM   3511 O O    . GLU   A 1 237 ? 31.187  -54.229 121.667 1   127.049 ? 931  GLU   A O    1 ? 
ATOM   3512 C CB   . GLU   A 1 237 ? 33.344  -52.572 123.396 1   120.491 ? 931  GLU   A CB   1 ? 
ATOM   3513 C CG   . GLU   A 1 237 ? 32.209  -52.161 124.325 1   136.984 ? 931  GLU   A CG   1 ? 
ATOM   3514 C CD   . GLU   A 1 237 ? 32.524  -51.01  125.272 1   145.916 ? 931  GLU   A CD   1 ? 
ATOM   3515 O OE1  . GLU   A 1 237 ? 31.675  -50.852 126.175 1   132.587 ? 931  GLU   A OE1  1 ? 
ATOM   3516 O OE2  . GLU   A 1 237 ? 33.562  -50.303 125.185 1   147.518 ? 931  GLU   A OE2  1 ? 
ATOM   3517 H H    . GLU   A 1 237 ? 34.152  -53.403 121.193 1   111.509 ? 931  GLU   A H    1 c 
ATOM   3518 H HA   . GLU   A 1 237 ? 33.634  -54.616 123.582 1   107.909 ? 931  GLU   A HA   1 c 
ATOM   3519 H HB2  . GLU   A 1 237 ? 34.194  -52.477 123.874 1   119.652 ? 931  GLU   A HB2  1 c 
ATOM   3520 H HB3  . GLU   A 1 237 ? 33.371  -51.978 122.62  1   119.439 ? 931  GLU   A HB3  1 c 
ATOM   3521 H HG2  . GLU   A 1 237 ? 31.426  -51.915 123.79  1   134.638 ? 931  GLU   A HG2  1 c 
ATOM   3522 H HG3  . GLU   A 1 237 ? 31.954  -52.931 124.872 1   134.313 ? 931  GLU   A HG3  1 c 
ATOM   3523 N N    . ARG   A 1 238 ? 31.127  -54.919 123.819 1   120.989 ? 932  ARG   A N    1 ? 
ATOM   3524 C CA   . ARG   A 1 238 ? 29.722  -55.309 123.81  1   104.606 ? 932  ARG   A CA   1 ? 
ATOM   3525 C C    . ARG   A 1 238 ? 29.065  -54.955 125.14  1   96.824  ? 932  ARG   A C    1 ? 
ATOM   3526 O O    . ARG   A 1 238 ? 29.689  -54.36  126     1   116.368 ? 932  ARG   A O    1 ? 
ATOM   3527 C CB   . ARG   A 1 238 ? 29.6    -56.813 123.56  1   100.151 ? 932  ARG   A CB   1 ? 
ATOM   3528 C CG   . ARG   A 1 238 ? 30.102  -57.25  122.193 1   107.177 ? 932  ARG   A CG   1 ? 
ATOM   3529 C CD   . ARG   A 1 238 ? 29.134  -56.82  121.105 1   108.374 ? 932  ARG   A CD   1 ? 
ATOM   3530 N NE   . ARG   A 1 238 ? 29.54   -57.315 119.784 1   104.727 ? 932  ARG   A NE   1 ? 
ATOM   3531 C CZ   . ARG   A 1 238 ? 30.546  -56.836 119.06  1   103.121 ? 932  ARG   A CZ   1 ? 
ATOM   3532 N NH1  . ARG   A 1 238 ? 31.264  -55.816 119.497 1   113.272 ? 932  ARG   A NH1  1 ? 
ATOM   3533 N NH2  . ARG   A 1 238 ? 30.833  -57.381 117.893 1   105.175 ? 932  ARG   A NH2  1 ? 
ATOM   3534 H H    . ARG   A 1 238 ? 31.607  -55.043 124.587 1   114.472 ? 932  ARG   A H    1 c 
ATOM   3535 H HA   . ARG   A 1 238 ? 29.258  -54.814 123.088 1   105.423 ? 932  ARG   A HA   1 c 
ATOM   3536 H HB2  . ARG   A 1 238 ? 30.11   -57.289 124.25  1   102.726 ? 932  ARG   A HB2  1 c 
ATOM   3537 H HB3  . ARG   A 1 238 ? 28.661  -57.079 123.648 1   102.737 ? 932  ARG   A HB3  1 c 
ATOM   3538 H HG2  . ARG   A 1 238 ? 30.984  -56.858 122.019 1   106.068 ? 932  ARG   A HG2  1 c 
ATOM   3539 H HG3  . ARG   A 1 238 ? 30.188  -58.226 122.177 1   105.855 ? 932  ARG   A HG3  1 c 
ATOM   3540 H HD2  . ARG   A 1 238 ? 28.244  -57.164 121.32  1   107     ? 932  ARG   A HD2  1 c 
ATOM   3541 H HD3  . ARG   A 1 238 ? 29.079  -55.844 121.081 1   107.299 ? 932  ARG   A HD3  1 c 
ATOM   3542 H HE   . ARG   A 1 238 ? 29.099  -57.983 119.449 1   104.847 ? 932  ARG   A HE   1 c 
ATOM   3543 H HH11 . ARG   A 1 238 ? 30.985  -55.326 120.176 1   109.964 ? 932  ARG   A HH11 1 c 
ATOM   3544 H HH12 . ARG   A 1 238 ? 32.026  -55.618 119.098 1   110.136 ? 932  ARG   A HH12 1 c 
ATOM   3545 H HH21 . ARG   A 1 238 ? 30.392  -58.096 117.618 1   104.574 ? 932  ARG   A HH21 1 c 
ATOM   3546 H HH22 . ARG   A 1 238 ? 31.465  -57.028 117.385 1   104.676 ? 932  ARG   A HH22 1 c 
ATOM   3547 N N    . LEU   A 1 239 ? 27.791  -55.305 125.298 1   105.811 ? 933  LEU   A N    1 ? 
ATOM   3548 C CA   . LEU   A 1 239 ? 27.085  -55.044 126.54  1   102.962 ? 933  LEU   A CA   1 ? 
ATOM   3549 C C    . LEU   A 1 239 ? 27.637  -55.925 127.654 1   103.056 ? 933  LEU   A C    1 ? 
ATOM   3550 O O    . LEU   A 1 239 ? 28.027  -57.07  127.425 1   100.463 ? 933  LEU   A O    1 ? 
ATOM   3551 C CB   . LEU   A 1 239 ? 25.59   -55.278 126.337 1   107.92  ? 933  LEU   A CB   1 ? 
ATOM   3552 C CG   . LEU   A 1 239 ? 24.907  -54.233 125.454 1   102.111 ? 933  LEU   A CG   1 ? 
ATOM   3553 C CD1  . LEU   A 1 239 ? 23.584  -54.704 124.895 1   97.066  ? 933  LEU   A CD1  1 ? 
ATOM   3554 C CD2  . LEU   A 1 239 ? 24.744  -52.963 126.26  1   102.835 ? 933  LEU   A CD2  1 ? 
ATOM   3555 H H    . LEU   A 1 239 ? 27.34   -55.701 124.608 1   103.002 ? 933  LEU   A H    1 c 
ATOM   3556 H HA   . LEU   A 1 239 ? 27.234  -54.097 126.783 1   104.309 ? 933  LEU   A HA   1 c 
ATOM   3557 H HB2  . LEU   A 1 239 ? 25.467  -56.165 125.926 1   105.374 ? 933  LEU   A HB2  1 c 
ATOM   3558 H HB3  . LEU   A 1 239 ? 25.15   -55.284 127.218 1   105.314 ? 933  LEU   A HB3  1 c 
ATOM   3559 H HG   . LEU   A 1 239 ? 25.507  -54.035 124.69  1   102.331 ? 933  LEU   A HG   1 c 
ATOM   3560 H HD11 . LEU   A 1 239 ? 23.727  -55.491 124.342 1   98.57   ? 933  LEU   A HD11 1 c 
ATOM   3561 H HD12 . LEU   A 1 239 ? 23.189  -53.998 124.357 1   98.545  ? 933  LEU   A HD12 1 c 
ATOM   3562 H HD13 . LEU   A 1 239 ? 22.984  -54.928 125.626 1   98.545  ? 933  LEU   A HD13 1 c 
ATOM   3563 H HD21 . LEU   A 1 239 ? 25.619  -52.604 126.485 1   102.639 ? 933  LEU   A HD21 1 c 
ATOM   3564 H HD22 . LEU   A 1 239 ? 24.254  -53.156 127.076 1   102.643 ? 933  LEU   A HD22 1 c 
ATOM   3565 H HD23 . LEU   A 1 239 ? 24.253  -52.308 125.736 1   102.628 ? 933  LEU   A HD23 1 c 
ATOM   3566 N N    . PRO   A 1 240 ? 27.587  -55.436 128.91  1   98.706  ? 934  PRO   A N    1 ? 
ATOM   3567 C CA   . PRO   A 1 240 ? 28.096  -56.182 130.049 1   94.161  ? 934  PRO   A CA   1 ? 
ATOM   3568 C C    . PRO   A 1 240 ? 27.216  -57.37  130.433 1   97.587  ? 934  PRO   A C    1 ? 
ATOM   3569 O O    . PRO   A 1 240 ? 26.027  -57.392 130.151 1   104.982 ? 934  PRO   A O    1 ? 
ATOM   3570 C CB   . PRO   A 1 240 ? 28.062  -55.154 131.163 1   98.53   ? 934  PRO   A CB   1 ? 
ATOM   3571 C CG   . PRO   A 1 240 ? 26.826  -54.344 130.807 1   98.684  ? 934  PRO   A CG   1 ? 
ATOM   3572 C CD   . PRO   A 1 240 ? 26.878  -54.211 129.315 1   97.708  ? 934  PRO   A CD   1 ? 
ATOM   3573 H HA   . PRO   A 1 240 ? 29.014  -56.479 129.876 1   96.471  ? 934  PRO   A HA   1 c 
ATOM   3574 H HB2  . PRO   A 1 240 ? 27.968  -55.58  132.038 1   97.561  ? 934  PRO   A HB2  1 c 
ATOM   3575 H HB3  . PRO   A 1 240 ? 28.865  -54.597 131.154 1   97.56   ? 934  PRO   A HB3  1 c 
ATOM   3576 H HG2  . PRO   A 1 240 ? 26.012  -54.809 131.085 1   98.472  ? 934  PRO   A HG2  1 c 
ATOM   3577 H HG3  . PRO   A 1 240 ? 26.849  -53.464 131.233 1   98.434  ? 934  PRO   A HG3  1 c 
ATOM   3578 H HD2  . PRO   A 1 240 ? 25.982  -54.181 128.931 1   98.283  ? 934  PRO   A HD2  1 c 
ATOM   3579 H HD3  . PRO   A 1 240 ? 27.375  -53.415 129.045 1   98.221  ? 934  PRO   A HD3  1 c 
ATOM   3580 N N    . GLN   A 1 241 ? 27.811  -58.356 131.096 1   101.237 ? 935  GLN   A N    1 ? 
ATOM   3581 C CA   . GLN   A 1 241 ? 27.073  -59.489 131.615 1   95.227  ? 935  GLN   A CA   1 ? 
ATOM   3582 C C    . GLN   A 1 241 ? 26.181  -59.031 132.765 1   93.151  ? 935  GLN   A C    1 ? 
ATOM   3583 O O    . GLN   A 1 241 ? 26.633  -58.403 133.715 1   97.372  ? 935  GLN   A O    1 ? 
ATOM   3584 C CB   . GLN   A 1 241 ? 28.069  -60.524 132.109 1   94.043  ? 935  GLN   A CB   1 ? 
ATOM   3585 C CG   . GLN   A 1 241 ? 27.429  -61.715 132.795 1   86.46   ? 935  GLN   A CG   1 ? 
ATOM   3586 C CD   . GLN   A 1 241 ? 28.418  -62.843 132.848 1   88.801  ? 935  GLN   A CD   1 ? 
ATOM   3587 O OE1  . GLN   A 1 241 ? 29.557  -62.708 132.385 1   84.674  ? 935  GLN   A OE1  1 ? 
ATOM   3588 N NE2  . GLN   A 1 241 ? 27.984  -63.955 133.41  1   103.881 ? 935  GLN   A NE2  1 ? 
ATOM   3589 H H    . GLN   A 1 241 ? 28.714  -58.32  131.232 1   98.833  ? 935  GLN   A H    1 c 
ATOM   3590 H HA   . GLN   A 1 241 ? 26.525  -59.875 130.889 1   95.931  ? 935  GLN   A HA   1 c 
ATOM   3591 H HB2  . GLN   A 1 241 ? 28.594  -60.836 131.347 1   92.435  ? 935  GLN   A HB2  1 c 
ATOM   3592 H HB3  . GLN   A 1 241 ? 28.685  -60.092 132.736 1   92.538  ? 935  GLN   A HB3  1 c 
ATOM   3593 H HG2  . GLN   A 1 241 ? 27.157  -61.471 133.703 1   88.834  ? 935  GLN   A HG2  1 c 
ATOM   3594 H HG3  . GLN   A 1 241 ? 26.631  -61.997 132.299 1   88.696  ? 935  GLN   A HG3  1 c 
ATOM   3595 H HE21 . GLN   A 1 241 ? 28.516  -64.664 133.455 1   98.833  ? 935  GLN   A HE21 1 c 
ATOM   3596 H HE22 . GLN   A 1 241 ? 27.163  -63.995 133.744 1   98.847  ? 935  GLN   A HE22 1 c 
ATOM   3597 N N    . PRO   A 1 242 ? 24.867  -59.295 132.687 1   99.974  ? 936  PRO   A N    1 ? 
ATOM   3598 C CA   . PRO   A 1 242 ? 23.959  -59.032 133.796 1   97.849  ? 936  PRO   A CA   1 ? 
ATOM   3599 C C    . PRO   A 1 242 ? 24.228  -59.859 135.049 1   100.248 ? 936  PRO   A C    1 ? 
ATOM   3600 O O    . PRO   A 1 242 ? 24.594  -61.032 134.995 1   112.54  ? 936  PRO   A O    1 ? 
ATOM   3601 C CB   . PRO   A 1 242 ? 22.586  -59.346 133.226 1   98.178  ? 936  PRO   A CB   1 ? 
ATOM   3602 C CG   . PRO   A 1 242 ? 22.789  -59.211 131.72  1   103.762 ? 936  PRO   A CG   1 ? 
ATOM   3603 C CD   . PRO   A 1 242 ? 24.174  -59.702 131.458 1   101.766 ? 936  PRO   A CD   1 ? 
ATOM   3604 H HA   . PRO   A 1 242 ? 24      -58.081 134.016 1   98.74   ? 936  PRO   A HA   1 c 
ATOM   3605 H HB2  . PRO   A 1 242 ? 22.306  -60.251 133.462 1   99.363  ? 936  PRO   A HB2  1 c 
ATOM   3606 H HB3  . PRO   A 1 242 ? 21.919  -58.709 133.548 1   99.451  ? 936  PRO   A HB3  1 c 
ATOM   3607 H HG2  . PRO   A 1 242 ? 22.136  -59.752 131.232 1   102.028 ? 936  PRO   A HG2  1 c 
ATOM   3608 H HG3  . PRO   A 1 242 ? 22.697  -58.279 131.439 1   102.028 ? 936  PRO   A HG3  1 c 
ATOM   3609 H HD2  . PRO   A 1 242 ? 24.198  -60.672 131.346 1   101.775 ? 936  PRO   A HD2  1 c 
ATOM   3610 H HD3  . PRO   A 1 242 ? 24.559  -59.271 130.674 1   101.728 ? 936  PRO   A HD3  1 c 
ATOM   3611 N N    . PRO   A 1 243 ? 24.119  -59.221 136.226 1   98.336  ? 937  PRO   A N    1 ? 
ATOM   3612 C CA   . PRO   A 1 243 ? 24.296  -59.891 137.503 1   100.945 ? 937  PRO   A CA   1 ? 
ATOM   3613 C C    . PRO   A 1 243 ? 23.601  -61.241 137.616 1   97.154  ? 937  PRO   A C    1 ? 
ATOM   3614 O O    . PRO   A 1 243 ? 24.201  -62.187 138.122 1   111.798 ? 937  PRO   A O    1 ? 
ATOM   3615 C CB   . PRO   A 1 243 ? 23.715  -58.896 138.499 1   98.285  ? 937  PRO   A CB   1 ? 
ATOM   3616 C CG   . PRO   A 1 243 ? 24.007  -57.559 137.849 1   101.159 ? 937  PRO   A CG   1 ? 
ATOM   3617 C CD   . PRO   A 1 243 ? 23.972  -57.77  136.361 1   97.821  ? 937  PRO   A CD   1 ? 
ATOM   3618 H HA   . PRO   A 1 243 ? 25.254  -60.004 137.678 1   99.313  ? 937  PRO   A HA   1 c 
ATOM   3619 H HB2  . PRO   A 1 243 ? 22.754  -59.03  138.612 1   99.457  ? 937  PRO   A HB2  1 c 
ATOM   3620 H HB3  . PRO   A 1 243 ? 24.157  -58.97  139.367 1   99.51   ? 937  PRO   A HB3  1 c 
ATOM   3621 H HG2  . PRO   A 1 243 ? 23.336  -56.898 138.112 1   99.732  ? 937  PRO   A HG2  1 c 
ATOM   3622 H HG3  . PRO   A 1 243 ? 24.887  -57.231 138.122 1   99.732  ? 937  PRO   A HG3  1 c 
ATOM   3623 H HD2  . PRO   A 1 243 ? 23.126  -57.466 135.98  1   98.829  ? 937  PRO   A HD2  1 c 
ATOM   3624 H HD3  . PRO   A 1 243 ? 24.71   -57.304 135.922 1   98.708  ? 937  PRO   A HD3  1 c 
ATOM   3625 N N    . ILE   A 1 244 ? 22.329  -61.291 137.198 1   89.774  ? 938  ILE   A N    1 ? 
ATOM   3626 C CA   . ILE   A 1 244 ? 21.511  -62.484 137.353 1   94.549  ? 938  ILE   A CA   1 ? 
ATOM   3627 C C    . ILE   A 1 244 ? 22.018  -63.564 136.402 1   94.84   ? 938  ILE   A C    1 ? 
ATOM   3628 O O    . ILE   A 1 244 ? 21.713  -64.739 136.591 1   87.107  ? 938  ILE   A O    1 ? 
ATOM   3629 C CB   . ILE   A 1 244 ? 20.017  -62.193 137.111 1   97.041  ? 938  ILE   A CB   1 ? 
ATOM   3630 C CG1  . ILE   A 1 244 ? 19.72   -61.901 135.642 1   106.091 ? 938  ILE   A CG1  1 ? 
ATOM   3631 C CG2  . ILE   A 1 244 ? 19.531  -61.059 138.004 1   96.179  ? 938  ILE   A CG2  1 ? 
ATOM   3632 C CD1  . ILE   A 1 244 ? 18.268  -62.099 135.254 1   96.87   ? 938  ILE   A CD1  1 ? 
ATOM   3633 H H    . ILE   A 1 244 ? 21.964  -60.557 136.795 1   92.822  ? 938  ILE   A H    1 c 
ATOM   3634 H HA   . ILE   A 1 244 ? 21.614  -62.807 138.269 1   94.129  ? 938  ILE   A HA   1 c 
ATOM   3635 H HB   . ILE   A 1 244 ? 19.517  -62.997 137.356 1   98.038  ? 938  ILE   A HB   1 c 
ATOM   3636 H HG12 . ILE   A 1 244 ? 19.972  -60.975 135.449 1   101.874 ? 938  ILE   A HG12 1 c 
ATOM   3637 H HG13 . ILE   A 1 244 ? 20.272  -62.482 135.083 1   101.715 ? 938  ILE   A HG13 1 c 
ATOM   3638 H HG21 . ILE   A 1 244 ? 18.563  -60.993 137.948 1   96.439  ? 938  ILE   A HG21 1 c 
ATOM   3639 H HG22 . ILE   A 1 244 ? 19.927  -60.22  137.717 1   96.523  ? 938  ILE   A HG22 1 c 
ATOM   3640 H HG23 . ILE   A 1 244 ? 19.787  -61.237 138.925 1   96.451  ? 938  ILE   A HG23 1 c 
ATOM   3641 H HD11 . ILE   A 1 244 ? 17.979  -62.995 135.514 1   99.452  ? 938  ILE   A HD11 1 c 
ATOM   3642 H HD12 . ILE   A 1 244 ? 18.171  -61.995 134.289 1   99.424  ? 938  ILE   A HD12 1 c 
ATOM   3643 H HD13 . ILE   A 1 244 ? 17.715  -61.436 135.709 1   99.48   ? 938  ILE   A HD13 1 c 
ATOM   3644 N N    . CYS   A 1 245 ? 22.772  -63.157 135.372 1   97.085  ? 939  CYS   A N    1 ? 
ATOM   3645 C CA   . CYS   A 1 245 ? 23.083  -64.027 134.246 1   97.98   ? 939  CYS   A CA   1 ? 
ATOM   3646 C C    . CYS   A 1 245 ? 24.247  -64.948 134.546 1   95.435  ? 939  CYS   A C    1 ? 
ATOM   3647 O O    . CYS   A 1 245 ? 25.294  -64.476 134.966 1   113.787 ? 939  CYS   A O    1 ? 
ATOM   3648 C CB   . CYS   A 1 245 ? 23.502  -63.239 133.014 1   98.196  ? 939  CYS   A CB   1 ? 
ATOM   3649 S SG   . CYS   A 1 245 ? 22.092  -62.922 131.938 1   100.623 ? 939  CYS   A SG   1 ? 
ATOM   3650 H H    . CYS   A 1 245 ? 23.097  -62.305 135.364 1   96.718  ? 939  CYS   A H    1 c 
ATOM   3651 H HA   . CYS   A 1 245 ? 22.282  -64.574 134.04  1   97.222  ? 939  CYS   A HA   1 c 
ATOM   3652 H HB2  . CYS   A 1 245 ? 23.896  -62.382 133.284 1   98.668  ? 939  CYS   A HB2  1 c 
ATOM   3653 H HB3  . CYS   A 1 245 ? 24.178  -63.745 132.511 1   98.593  ? 939  CYS   A HB3  1 c 
ATOM   3654 H HG   . CYS   A 1 245 ? 22.701  -62.281 131.072 0   101.06  ? 939  CYS   A HG   1 c 
ATOM   3655 N N    . THR   A 1 246 ? 24.054  -66.244 134.275 1   89.453  ? 940  THR   A N    1 ? 
ATOM   3656 C CA   . THR   A 1 246 ? 25.155  -67.183 134.253 1   89.875  ? 940  THR   A CA   1 ? 
ATOM   3657 C C    . THR   A 1 246 ? 25.896  -67.016 132.937 1   92.276  ? 940  THR   A C    1 ? 
ATOM   3658 O O    . THR   A 1 246 ? 25.427  -66.348 132.031 1   85.787  ? 940  THR   A O    1 ? 
ATOM   3659 C CB   . THR   A 1 246 ? 24.674  -68.618 134.425 1   93.98   ? 940  THR   A CB   1 ? 
ATOM   3660 O OG1  . THR   A 1 246 ? 23.709  -68.906 133.42  1   86.51   ? 940  THR   A OG1  1 ? 
ATOM   3661 C CG2  . THR   A 1 246 ? 24.111  -68.835 135.814 1   108.729 ? 940  THR   A CG2  1 ? 
ATOM   3662 H H    . THR   A 1 246 ? 23.21   -66.549 134.1   1   91.057  ? 940  THR   A H    1 c 
ATOM   3663 H HA   . THR   A 1 246 ? 25.766  -66.968 134.991 1   91.107  ? 940  THR   A HA   1 c 
ATOM   3664 H HB   . THR   A 1 246 ? 25.438  -69.23  134.307 1   94.271  ? 940  THR   A HB   1 c 
ATOM   3665 H HG1  . THR   A 1 246 ? 23.046  -68.383 133.515 0   86.73   ? 940  THR   A HG1  1 c 
ATOM   3666 H HG21 . THR   A 1 246 ? 23.804  -69.752 135.9   1   103.992 ? 940  THR   A HG21 1 c 
ATOM   3667 H HG22 . THR   A 1 246 ? 23.365  -68.229 135.961 1   103.897 ? 940  THR   A HG22 1 c 
ATOM   3668 H HG23 . THR   A 1 246 ? 24.802  -68.662 136.475 1   104.051 ? 940  THR   A HG23 1 c 
ATOM   3669 N N    . ILE   A 1 247 ? 27.071  -67.633 132.85  1   99.362  ? 941  ILE   A N    1 ? 
ATOM   3670 C CA   . ILE   A 1 247 ? 27.879  -67.533 131.653 1   93.698  ? 941  ILE   A CA   1 ? 
ATOM   3671 C C    . ILE   A 1 247 ? 27.137  -68.195 130.492 1   88.087  ? 941  ILE   A C    1 ? 
ATOM   3672 O O    . ILE   A 1 247 ? 27.275  -67.749 129.37  1   99.681  ? 941  ILE   A O    1 ? 
ATOM   3673 C CB   . ILE   A 1 247 ? 29.29   -68.118 131.868 1   101.14  ? 941  ILE   A CB   1 ? 
ATOM   3674 C CG1  . ILE   A 1 247 ? 30.261  -67.596 130.811 1   98.674  ? 941  ILE   A CG1  1 ? 
ATOM   3675 C CG2  . ILE   A 1 247 ? 29.271  -69.646 131.915 1   115.787 ? 941  ILE   A CG2  1 ? 
ATOM   3676 C CD1  . ILE   A 1 247 ? 31.487  -68.457 130.613 1   96.002  ? 941  ILE   A CD1  1 ? 
ATOM   3677 H H    . ILE   A 1 247 ? 27.379  -68.126 133.555 1   96.335  ? 941  ILE   A H    1 c 
ATOM   3678 H HA   . ILE   A 1 247 ? 27.981  -66.585 131.442 1   94.97   ? 941  ILE   A HA   1 c 
ATOM   3679 H HB   . ILE   A 1 247 ? 29.608  -67.802 132.736 1   101.764 ? 941  ILE   A HB   1 c 
ATOM   3680 H HG12 . ILE   A 1 247 ? 29.789  -67.524 129.957 1   98.527  ? 941  ILE   A HG12 1 c 
ATOM   3681 H HG13 . ILE   A 1 247 ? 30.549  -66.697 131.069 1   98.588  ? 941  ILE   A HG13 1 c 
ATOM   3682 H HG21 . ILE   A 1 247 ? 30.068  -69.969 132.368 1   110.976 ? 941  ILE   A HG21 1 c 
ATOM   3683 H HG22 . ILE   A 1 247 ? 29.249  -69.998 131.011 1   110.873 ? 941  ILE   A HG22 1 c 
ATOM   3684 H HG23 . ILE   A 1 247 ? 28.483  -69.947 132.398 1   111.03  ? 941  ILE   A HG23 1 c 
ATOM   3685 H HD11 . ILE   A 1 247 ? 31.861  -68.701 131.481 1   97.006  ? 941  ILE   A HD11 1 c 
ATOM   3686 H HD12 . ILE   A 1 247 ? 32.152  -67.954 130.106 1   96.874  ? 941  ILE   A HD12 1 c 
ATOM   3687 H HD13 . ILE   A 1 247 ? 31.252  -69.266 130.121 1   97.013  ? 941  ILE   A HD13 1 c 
ATOM   3688 N N    . ASP   A 1 248 ? 26.332  -69.233 130.747 1   89.763  ? 942  ASP   A N    1 ? 
ATOM   3689 C CA   . ASP   A 1 248 ? 25.653  -69.946 129.674 1   88.82   ? 942  ASP   A CA   1 ? 
ATOM   3690 C C    . ASP   A 1 248 ? 24.659  -69.017 128.984 1   84.485  ? 942  ASP   A C    1 ? 
ATOM   3691 O O    . ASP   A 1 248 ? 24.573  -69.002 127.774 1   87.819  ? 942  ASP   A O    1 ? 
ATOM   3692 C CB   . ASP   A 1 248 ? 24.933  -71.178 130.191 1   92.858  ? 942  ASP   A CB   1 ? 
ATOM   3693 C CG   . ASP   A 1 248 ? 25.683  -71.974 131.24  1   91.631  ? 942  ASP   A CG   1 ? 
ATOM   3694 O OD1  . ASP   A 1 248 ? 25.44   -71.759 132.449 1   104.455 ? 942  ASP   A OD1  1 ? 
ATOM   3695 O OD2  . ASP   A 1 248 ? 26.433  -72.845 130.829 1   101.626 ? 942  ASP   A OD2  1 ? 
ATOM   3696 H H    . ASP   A 1 248 ? 26.201  -69.502 131.61  1   89.303  ? 942  ASP   A H    1 c 
ATOM   3697 H HA   . ASP   A 1 248 ? 26.327  -70.233 129.016 1   88.964  ? 942  ASP   A HA   1 c 
ATOM   3698 H HB2  . ASP   A 1 248 ? 24.075  -70.904 130.578 1   91.683  ? 942  ASP   A HB2  1 c 
ATOM   3699 H HB3  . ASP   A 1 248 ? 24.746  -71.771 129.434 1   91.703  ? 942  ASP   A HB3  1 c 
ATOM   3700 N N    . VAL   A 1 249 ? 23.875  -68.269 129.76  1   89.092  ? 943  VAL   A N    1 ? 
ATOM   3701 C CA   . VAL   A 1 249 ? 22.888  -67.359 129.202 1   83.635  ? 943  VAL   A CA   1 ? 
ATOM   3702 C C    . VAL   A 1 249 ? 23.594  -66.189 128.533 1   79.883  ? 943  VAL   A C    1 ? 
ATOM   3703 O O    . VAL   A 1 249 ? 23.182  -65.736 127.491 1   84.285  ? 943  VAL   A O    1 ? 
ATOM   3704 C CB   . VAL   A 1 249 ? 21.924  -66.843 130.285 1   92.524  ? 943  VAL   A CB   1 ? 
ATOM   3705 C CG1  . VAL   A 1 249 ? 20.931  -65.837 129.728 1   90.555  ? 943  VAL   A CG1  1 ? 
ATOM   3706 C CG2  . VAL   A 1 249 ? 21.198  -67.977 130.999 1   103.343 ? 943  VAL   A CG2  1 ? 
ATOM   3707 H H    . VAL   A 1 249 ? 23.961  -68.323 130.668 1   86.978  ? 943  VAL   A H    1 c 
ATOM   3708 H HA   . VAL   A 1 249 ? 22.37   -67.839 128.527 1   85.519  ? 943  VAL   A HA   1 c 
ATOM   3709 H HB   . VAL   A 1 249 ? 22.473  -66.374 130.957 1   92.323  ? 943  VAL   A HB   1 c 
ATOM   3710 H HG11 . VAL   A 1 249 ? 20.511  -66.202 128.931 1   91.193  ? 943  VAL   A HG11 1 c 
ATOM   3711 H HG12 . VAL   A 1 249 ? 21.391  -65.013 129.503 1   91.276  ? 943  VAL   A HG12 1 c 
ATOM   3712 H HG13 . VAL   A 1 249 ? 20.249  -65.652 130.396 1   91.305  ? 943  VAL   A HG13 1 c 
ATOM   3713 H HG21 . VAL   A 1 249 ? 20.597  -67.607 131.668 1   99.893  ? 943  VAL   A HG21 1 c 
ATOM   3714 H HG22 . VAL   A 1 249 ? 21.845  -68.557 131.434 1   99.738  ? 943  VAL   A HG22 1 c 
ATOM   3715 H HG23 . VAL   A 1 249 ? 20.685  -68.49  130.354 1   99.928  ? 943  VAL   A HG23 1 c 
ATOM   3716 N N    . TYR   A 1 250 ? 24.646  -65.671 129.156 1   90.274  ? 944  TYR   A N    1 ? 
ATOM   3717 C CA   . TYR   A 1 250 ? 25.35   -64.516 128.634 1   87.888  ? 944  TYR   A CA   1 ? 
ATOM   3718 C C    . TYR   A 1 250 ? 26.037  -64.841 127.31  1   84.71   ? 944  TYR   A C    1 ? 
ATOM   3719 O O    . TYR   A 1 250 ? 26.112  -63.995 126.441 1   103.382 ? 944  TYR   A O    1 ? 
ATOM   3720 C CB   . TYR   A 1 250 ? 26.399  -64.005 129.624 1   93.641  ? 944  TYR   A CB   1 ? 
ATOM   3721 C CG   . TYR   A 1 250 ? 27.064  -62.73  129.139 1   91.475  ? 944  TYR   A CG   1 ? 
ATOM   3722 C CD1  . TYR   A 1 250 ? 26.324  -61.767 128.481 1   107.704 ? 944  TYR   A CD1  1 ? 
ATOM   3723 C CD2  . TYR   A 1 250 ? 28.418  -62.508 129.29  1   92.225  ? 944  TYR   A CD2  1 ? 
ATOM   3724 C CE1  . TYR   A 1 250 ? 26.906  -60.61  128.007 1   100.249 ? 944  TYR   A CE1  1 ? 
ATOM   3725 C CE2  . TYR   A 1 250 ? 29.016  -61.352 128.827 1   90.003  ? 944  TYR   A CE2  1 ? 
ATOM   3726 C CZ   . TYR   A 1 250 ? 28.255  -60.393 128.197 1   91.665  ? 944  TYR   A CZ   1 ? 
ATOM   3727 O OH   . TYR   A 1 250 ? 28.879  -59.274 127.758 1   96.885  ? 944  TYR   A OH   1 ? 
ATOM   3728 H H    . TYR   A 1 250 ? 24.934  -66.044 129.939 1   87.179  ? 944  TYR   A H    1 c 
ATOM   3729 H HA   . TYR   A 1 250 ? 24.685  -63.797 128.476 1   88.893  ? 944  TYR   A HA   1 c 
ATOM   3730 H HB2  . TYR   A 1 250 ? 25.963  -63.834 130.489 1   91.813  ? 944  TYR   A HB2  1 c 
ATOM   3731 H HB3  . TYR   A 1 250 ? 27.083  -64.7   129.75  1   91.813  ? 944  TYR   A HB3  1 c 
ATOM   3732 H HD1  . TYR   A 1 250 ? 25.398  -61.896 128.357 1   101.471 ? 944  TYR   A HD1  1 c 
ATOM   3733 H HD2  . TYR   A 1 250 ? 28.947  -63.155 129.73  1   91.675  ? 944  TYR   A HD2  1 c 
ATOM   3734 H HE1  . TYR   A 1 250 ? 26.379  -59.957 127.579 1   99.667  ? 944  TYR   A HE1  1 c 
ATOM   3735 H HE2  . TYR   A 1 250 ? 29.939  -61.212 128.954 1   91.079  ? 944  TYR   A HE2  1 c 
ATOM   3736 H HH   . TYR   A 1 250 ? 28.337  -58.781 127.355 0   96.52   ? 944  TYR   A HH   1 c 
ATOM   3737 N N    . MET   A 1 251 ? 26.56   -66.056 127.171 1   92.019  ? 945  MET   A N    1 ? 
ATOM   3738 C CA   . MET   A 1 251 ? 27.205  -66.509 125.948 1   99.193  ? 945  MET   A CA   1 ? 
ATOM   3739 C C    . MET   A 1 251 ? 26.251  -66.479 124.768 1   94.139  ? 945  MET   A C    1 ? 
ATOM   3740 O O    . MET   A 1 251 ? 26.649  -66.154 123.663 1   108.73  ? 945  MET   A O    1 ? 
ATOM   3741 C CB   . MET   A 1 251 ? 27.635  -67.972 126.064 1   112.922 ? 945  MET   A CB   1 ? 
ATOM   3742 C CG   . MET   A 1 251 ? 28.869  -68.167 126.898 1   123.135 ? 945  MET   A CG   1 ? 
ATOM   3743 S SD   . MET   A 1 251 ? 30.331  -68.108 125.843 1   127.665 ? 945  MET   A SD   1 ? 
ATOM   3744 C CE   . MET   A 1 251 ? 31.503  -68.395 127.177 1   141.218 ? 945  MET   A CE   1 ? 
ATOM   3745 H H    . MET   A 1 251 ? 26.521  -66.634 127.878 1   91.994  ? 945  MET   A H    1 c 
ATOM   3746 H HA   . MET   A 1 251 ? 27.989  -65.933 125.76  1   99.108  ? 945  MET   A HA   1 c 
ATOM   3747 H HB2  . MET   A 1 251 ? 26.899  -68.486 126.458 1   111.706 ? 945  MET   A HB2  1 c 
ATOM   3748 H HB3  . MET   A 1 251 ? 27.799  -68.325 125.163 1   111.793 ? 945  MET   A HB3  1 c 
ATOM   3749 H HG2  . MET   A 1 251 ? 28.931  -67.463 127.572 1   121.139 ? 945  MET   A HG2  1 c 
ATOM   3750 H HG3  . MET   A 1 251 ? 28.83   -69.032 127.354 1   121.456 ? 945  MET   A HG3  1 c 
ATOM   3751 H HE1  . MET   A 1 251 ? 32.374  -68.621 126.802 1   137.671 ? 945  MET   A HE1  1 c 
ATOM   3752 H HE2  . MET   A 1 251 ? 31.58   -67.589 127.72  1   137.672 ? 945  MET   A HE2  1 c 
ATOM   3753 H HE3  . MET   A 1 251 ? 31.183  -69.128 127.735 1   137.574 ? 945  MET   A HE3  1 c 
ATOM   3754 N N    . ILE   A 1 252 ? 25.005  -66.868 125.004 1   92.159  ? 946  ILE   A N    1 ? 
ATOM   3755 C CA   . ILE   A 1 252 ? 23.997  -66.811 123.965 1   96.519  ? 946  ILE   A CA   1 ? 
ATOM   3756 C C    . ILE   A 1 252 ? 23.854  -65.38  123.454 1   87.825  ? 946  ILE   A C    1 ? 
ATOM   3757 O O    . ILE   A 1 252 ? 23.769  -65.163 122.257 1   91.881  ? 946  ILE   A O    1 ? 
ATOM   3758 C CB   . ILE   A 1 252 ? 22.655  -67.368 124.469 1   99.971  ? 946  ILE   A CB   1 ? 
ATOM   3759 C CG1  . ILE   A 1 252 ? 22.706  -68.87  124.721 1   109.856 ? 946  ILE   A CG1  1 ? 
ATOM   3760 C CG2  . ILE   A 1 252 ? 21.544  -67.01  123.497 1   100.164 ? 946  ILE   A CG2  1 ? 
ATOM   3761 C CD1  . ILE   A 1 252 ? 23.605  -69.646 123.764 1   124.493 ? 946  ILE   A CD1  1 ? 
ATOM   3762 H H    . ILE   A 1 252 ? 24.774  -67.185 125.829 1   93.793  ? 946  ILE   A H    1 c 
ATOM   3763 H HA   . ILE   A 1 252 ? 24.298  -67.364 123.221 1   95.1    ? 946  ILE   A HA   1 c 
ATOM   3764 H HB   . ILE   A 1 252 ? 22.455  -66.933 125.321 1   100.983 ? 946  ILE   A HB   1 c 
ATOM   3765 H HG12 . ILE   A 1 252 ? 23.02   -69.021 125.636 1   110.457 ? 946  ILE   A HG12 1 c 
ATOM   3766 H HG13 . ILE   A 1 252 ? 21.798  -69.231 124.658 1   110.454 ? 946  ILE   A HG13 1 c 
ATOM   3767 H HG21 . ILE   A 1 252 ? 20.745  -67.52  123.712 1   100.204 ? 946  ILE   A HG21 1 c 
ATOM   3768 H HG22 . ILE   A 1 252 ? 21.824  -67.22  122.59  1   100.059 ? 946  ILE   A HG22 1 c 
ATOM   3769 H HG23 . ILE   A 1 252 ? 21.344  -66.061 123.562 1   100.047 ? 946  ILE   A HG23 1 c 
ATOM   3770 H HD11 . ILE   A 1 252 ? 23.438  -69.36  122.846 1   119.57  ? 946  ILE   A HD11 1 c 
ATOM   3771 H HD12 . ILE   A 1 252 ? 23.409  -70.599 123.844 1   119.82  ? 946  ILE   A HD12 1 c 
ATOM   3772 H HD13 . ILE   A 1 252 ? 24.543  -69.492 123.988 1   119.574 ? 946  ILE   A HD13 1 c 
ATOM   3773 N N    . MET   A 1 253 ? 23.772  -64.412 124.362 1   84.249  ? 947  MET   A N    1 ? 
ATOM   3774 C CA   . MET   A 1 253 ? 23.704  -63.014 123.973 1   90.822  ? 947  MET   A CA   1 ? 
ATOM   3775 C C    . MET   A 1 253 ? 24.908  -62.604 123.121 1   89.215  ? 947  MET   A C    1 ? 
ATOM   3776 O O    . MET   A 1 253 ? 24.799  -61.884 122.134 1   97.081  ? 947  MET   A O    1 ? 
ATOM   3777 C CB   . MET   A 1 253 ? 23.669  -62.126 125.218 1   95.932  ? 947  MET   A CB   1 ? 
ATOM   3778 C CG   . MET   A 1 253 ? 22.36   -62.19  125.98  1   94.519  ? 947  MET   A CG   1 ? 
ATOM   3779 S SD   . MET   A 1 253 ? 22.461  -61.164 127.46  1   102.851 ? 947  MET   A SD   1 ? 
ATOM   3780 C CE   . MET   A 1 253 ? 21.463  -62.184 128.547 1   121.691 ? 947  MET   A CE   1 ? 
ATOM   3781 H H    . MET   A 1 253 ? 23.752  -64.625 125.25  1   86.754  ? 947  MET   A H    1 c 
ATOM   3782 H HA   . MET   A 1 253 ? 22.877  -62.877 123.445 1   90.088  ? 947  MET   A HA   1 c 
ATOM   3783 H HB2  . MET   A 1 253 ? 24.398  -62.393 125.816 1   94.436  ? 947  MET   A HB2  1 c 
ATOM   3784 H HB3  . MET   A 1 253 ? 23.831  -61.199 124.945 1   94.47   ? 947  MET   A HB3  1 c 
ATOM   3785 H HG2  . MET   A 1 253 ? 21.63   -61.87  125.413 1   96.408  ? 947  MET   A HG2  1 c 
ATOM   3786 H HG3  . MET   A 1 253 ? 22.17   -63.114 126.238 1   96.512  ? 947  MET   A HG3  1 c 
ATOM   3787 H HE1  . MET   A 1 253 ? 21.259  -61.682 129.357 1   116.024 ? 947  MET   A HE1  1 c 
ATOM   3788 H HE2  . MET   A 1 253 ? 20.637  -62.433 128.096 1   116.063 ? 947  MET   A HE2  1 c 
ATOM   3789 H HE3  . MET   A 1 253 ? 21.96   -62.99  128.78  1   116.2   ? 947  MET   A HE3  1 c 
ATOM   3790 N N    . VAL   A 1 254 ? 26.083  -63.06  123.53  1   96.657  ? 948  VAL   A N    1 ? 
ATOM   3791 C CA   . VAL   A 1 254 ? 27.326  -62.685 122.886 1   102.884 ? 948  VAL   A CA   1 ? 
ATOM   3792 C C    . VAL   A 1 254 ? 27.376  -63.214 121.46  1   94.796  ? 948  VAL   A C    1 ? 
ATOM   3793 O O    . VAL   A 1 254 ? 27.93   -62.556 120.577 1   98.055  ? 948  VAL   A O    1 ? 
ATOM   3794 C CB   . VAL   A 1 254 ? 28.507  -63.217 123.718 1   104.441 ? 948  VAL   A CB   1 ? 
ATOM   3795 C CG1  . VAL   A 1 254 ? 29.758  -63.432 122.878 1   111.327 ? 948  VAL   A CG1  1 ? 
ATOM   3796 C CG2  . VAL   A 1 254 ? 28.796  -62.299 124.897 1   101.644 ? 948  VAL   A CG2  1 ? 
ATOM   3797 H H    . VAL   A 1 254 ? 26.114  -63.623 124.249 1   96.168  ? 948  VAL   A H    1 c 
ATOM   3798 H HA   . VAL   A 1 254 ? 27.378  -61.71  122.859 1   100.329 ? 948  VAL   A HA   1 c 
ATOM   3799 H HB   . VAL   A 1 254 ? 28.239  -64.093 124.079 1   104.771 ? 948  VAL   A HB   1 c 
ATOM   3800 H HG11 . VAL   A 1 254 ? 29.932  -62.64  122.348 1   109.064 ? 948  VAL   A HG11 1 c 
ATOM   3801 H HG12 . VAL   A 1 254 ? 29.631  -64.195 122.289 1   109.105 ? 948  VAL   A HG12 1 c 
ATOM   3802 H HG13 . VAL   A 1 254 ? 30.516  -63.602 123.463 1   109.101 ? 948  VAL   A HG13 1 c 
ATOM   3803 H HG21 . VAL   A 1 254 ? 29.535  -62.659 125.416 1   102.501 ? 948  VAL   A HG21 1 c 
ATOM   3804 H HG22 . VAL   A 1 254 ? 28.007  -62.236 125.461 1   102.468 ? 948  VAL   A HG22 1 c 
ATOM   3805 H HG23 . VAL   A 1 254 ? 29.031  -61.414 124.57  1   102.457 ? 948  VAL   A HG23 1 c 
ATOM   3806 N N    . LYS   A 1 255 ? 26.854  -64.427 121.26  1   87.28   ? 949  LYS   A N    1 ? 
ATOM   3807 C CA   . LYS   A 1 255 ? 26.864  -65.043 119.943 1   88.118  ? 949  LYS   A CA   1 ? 
ATOM   3808 C C    . LYS   A 1 255 ? 25.989  -64.234 118.999 1   87.111  ? 949  LYS   A C    1 ? 
ATOM   3809 O O    . LYS   A 1 255 ? 26.281  -64.146 117.817 1   95.937  ? 949  LYS   A O    1 ? 
ATOM   3810 C CB   . LYS   A 1 255 ? 26.363  -66.483 120.025 1   88.905  ? 949  LYS   A CB   1 ? 
ATOM   3811 C CG   . LYS   A 1 255 ? 27.429  -67.449 120.469 1   94.282  ? 949  LYS   A CG   1 ? 
ATOM   3812 C CD   . LYS   A 1 255 ? 26.929  -68.555 121.384 1   101.906 ? 949  LYS   A CD   1 ? 
ATOM   3813 C CE   . LYS   A 1 255 ? 26.939  -69.904 120.742 1   104.089 ? 949  LYS   A CE   1 ? 
ATOM   3814 N NZ   . LYS   A 1 255 ? 27.002  -70.928 121.785 1   119.622 ? 949  LYS   A NZ   1 ? 
ATOM   3815 H H    . LYS   A 1 255 ? 26.49   -64.886 121.962 1   89.348  ? 949  LYS   A H    1 c 
ATOM   3816 H HA   . LYS   A 1 255 ? 27.794  -65.039 119.601 1   88.065  ? 949  LYS   A HA   1 c 
ATOM   3817 H HB2  . LYS   A 1 255 ? 25.61   -66.527 120.651 1   90.073  ? 949  LYS   A HB2  1 c 
ATOM   3818 H HB3  . LYS   A 1 255 ? 26.039  -66.762 119.143 1   89.942  ? 949  LYS   A HB3  1 c 
ATOM   3819 H HG2  . LYS   A 1 255 ? 27.834  -67.851 119.67  1   94.783  ? 949  LYS   A HG2  1 c 
ATOM   3820 H HG3  . LYS   A 1 255 ? 28.13   -66.945 120.936 1   94.607  ? 949  LYS   A HG3  1 c 
ATOM   3821 H HD2  . LYS   A 1 255 ? 27.495  -68.579 122.186 1   100.777 ? 949  LYS   A HD2  1 c 
ATOM   3822 H HD3  . LYS   A 1 255 ? 26.014  -68.348 121.673 1   100.495 ? 949  LYS   A HD3  1 c 
ATOM   3823 H HE2  . LYS   A 1 255 ? 26.131  -70.029 120.214 1   107.016 ? 949  LYS   A HE2  1 c 
ATOM   3824 H HE3  . LYS   A 1 255 ? 27.713  -69.996 120.158 1   106.887 ? 949  LYS   A HE3  1 c 
ATOM   3825 H HZ1  . LYS   A 1 255 ? 26.33   -70.804 122.38  1   114.495 ? 949  LYS   A HZ1  1 c 
ATOM   3826 H HZ2  . LYS   A 1 255 ? 27.796  -70.88  122.217 1   114.476 ? 949  LYS   A HZ2  1 c 
ATOM   3827 H HZ3  . LYS   A 1 255 ? 26.917  -71.749 121.41  1   114.556 ? 949  LYS   A HZ3  1 c 
ATOM   3828 N N    . CYS   A 1 256 ? 24.91   -63.669 119.549 1   105.667 ? 950  CYS   A N    1 ? 
ATOM   3829 C CA   . CYS   A 1 256 ? 23.977  -62.821 118.825 1   99.59   ? 950  CYS   A CA   1 ? 
ATOM   3830 C C    . CYS   A 1 256 ? 24.658  -61.546 118.33  1   92.77   ? 950  CYS   A C    1 ? 
ATOM   3831 O O    . CYS   A 1 256 ? 24.243  -60.982 117.324 1   102.783 ? 950  CYS   A O    1 ? 
ATOM   3832 C CB   . CYS   A 1 256 ? 22.791  -62.447 119.71  1   96.966  ? 950  CYS   A CB   1 ? 
ATOM   3833 S SG   . CYS   A 1 256 ? 21.662  -63.828 120.007 1   94.859  ? 950  CYS   A SG   1 ? 
ATOM   3834 H H    . CYS   A 1 256 ? 24.739  -63.835 120.431 1   99.315  ? 950  CYS   A H    1 c 
ATOM   3835 H HA   . CYS   A 1 256 ? 23.647  -63.326 118.04  1   98.878  ? 950  CYS   A HA   1 c 
ATOM   3836 H HB2  . CYS   A 1 256 ? 23.12   -62.12  120.575 1   97.185  ? 950  CYS   A HB2  1 c 
ATOM   3837 H HB3  . CYS   A 1 256 ? 22.286  -61.719 119.283 1   97.153  ? 950  CYS   A HB3  1 c 
ATOM   3838 H HG   . CYS   A 1 256 ? 20.865  -63.274 120.722 0   96.1    ? 950  CYS   A HG   1 c 
ATOM   3839 N N    . TRP   A 1 257 ? 25.686  -61.093 119.058 1   86.265  ? 951  TRP   A N    1 ? 
ATOM   3840 C CA   . TRP   A 1 257 ? 26.375  -59.85  118.762 1   86.413  ? 951  TRP   A CA   1 ? 
ATOM   3841 C C    . TRP   A 1 257 ? 27.679  -60.066 118.004 1   91.622  ? 951  TRP   A C    1 ? 
ATOM   3842 O O    . TRP   A 1 257 ? 28.518  -59.17  117.937 1   88.168  ? 951  TRP   A O    1 ? 
ATOM   3843 C CB   . TRP   A 1 257 ? 26.673  -59.117 120.062 1   91.404  ? 951  TRP   A CB   1 ? 
ATOM   3844 C CG   . TRP   A 1 257 ? 25.432  -58.824 120.833 1   88.68   ? 951  TRP   A CG   1 ? 
ATOM   3845 C CD1  . TRP   A 1 257 ? 24.206  -58.523 120.336 1   88.841  ? 951  TRP   A CD1  1 ? 
ATOM   3846 C CD2  . TRP   A 1 257 ? 25.325  -58.785 122.261 1   100.701 ? 951  TRP   A CD2  1 ? 
ATOM   3847 N NE1  . TRP   A 1 257 ? 23.335  -58.295 121.361 1   98.727  ? 951  TRP   A NE1  1 ? 
ATOM   3848 C CE2  . TRP   A 1 257 ? 23.99   -58.446 122.552 1   105.929 ? 951  TRP   A CE2  1 ? 
ATOM   3849 C CE3  . TRP   A 1 257 ? 26.218  -59.011 123.306 1   101.071 ? 951  TRP   A CE3  1 ? 
ATOM   3850 C CZ2  . TRP   A 1 257 ? 23.53   -58.315 123.857 1   105.768 ? 951  TRP   A CZ2  1 ? 
ATOM   3851 C CZ3  . TRP   A 1 257 ? 25.76   -58.887 124.597 1   110.428 ? 951  TRP   A CZ3  1 ? 
ATOM   3852 C CH2  . TRP   A 1 257 ? 24.438  -58.535 124.865 1   110.942 ? 951  TRP   A CH2  1 ? 
ATOM   3853 H H    . TRP   A 1 257 ? 25.959  -61.574 119.784 1   88.057  ? 951  TRP   A H    1 c 
ATOM   3854 H HA   . TRP   A 1 257 ? 25.779  -59.281 118.211 1   88.364  ? 951  TRP   A HA   1 c 
ATOM   3855 H HB2  . TRP   A 1 257 ? 27.272  -59.67  120.608 1   89.692  ? 951  TRP   A HB2  1 c 
ATOM   3856 H HB3  . TRP   A 1 257 ? 27.115  -58.27  119.846 1   90.007  ? 951  TRP   A HB3  1 c 
ATOM   3857 H HD1  . TRP   A 1 257 ? 23.98   -58.463 119.422 1   91.156  ? 951  TRP   A HD1  1 c 
ATOM   3858 H HE1  . TRP   A 1 257 ? 22.493  -58.082 121.269 1   97.801  ? 951  TRP   A HE1  1 c 
ATOM   3859 H HE3  . TRP   A 1 257 ? 27.115  -59.239 123.131 1   103.108 ? 951  TRP   A HE3  1 c 
ATOM   3860 H HZ2  . TRP   A 1 257 ? 22.635  -58.086 124.04  1   106.775 ? 951  TRP   A HZ2  1 c 
ATOM   3861 H HZ3  . TRP   A 1 257 ? 26.356  -59.027 125.314 1   108.123 ? 951  TRP   A HZ3  1 c 
ATOM   3862 H HH2  . TRP   A 1 257 ? 24.156  -58.461 125.76  1   109.392 ? 951  TRP   A HH2  1 c 
ATOM   3863 N N    . MET   A 1 258 ? 27.85   -61.247 117.421 1   103.065 ? 952  MET   A N    1 ? 
ATOM   3864 C CA   . MET   A 1 258 ? 29.009  -61.488 116.583 1   110.651 ? 952  MET   A CA   1 ? 
ATOM   3865 C C    . MET   A 1 258 ? 28.918  -60.729 115.265 1   117.973 ? 952  MET   A C    1 ? 
ATOM   3866 O O    . MET   A 1 258 ? 27.85   -60.623 114.681 1   117.265 ? 952  MET   A O    1 ? 
ATOM   3867 C CB   . MET   A 1 258 ? 29.178  -62.974 116.305 1   108.974 ? 952  MET   A CB   1 ? 
ATOM   3868 C CG   . MET   A 1 258 ? 30.294  -63.505 117.131 1   109.795 ? 952  MET   A CG   1 ? 
ATOM   3869 S SD   . MET   A 1 258 ? 30.038  -65.264 117.328 1   124.967 ? 952  MET   A SD   1 ? 
ATOM   3870 C CE   . MET   A 1 258 ? 30.879  -65.288 118.918 1   153.978 ? 952  MET   A CE   1 ? 
ATOM   3871 H H    . MET   A 1 258 ? 27.24   -61.916 117.542 1   101.637 ? 952  MET   A H    1 c 
ATOM   3872 H HA   . MET   A 1 258 ? 29.807  -61.157 117.07  1   110.064 ? 952  MET   A HA   1 c 
ATOM   3873 H HB2  . MET   A 1 258 ? 28.348  -63.448 116.52  1   109.439 ? 952  MET   A HB2  1 c 
ATOM   3874 H HB3  . MET   A 1 258 ? 29.378  -63.11  115.354 1   109.569 ? 952  MET   A HB3  1 c 
ATOM   3875 H HG2  . MET   A 1 258 ? 31.15   -63.343 116.688 1   112.41  ? 952  MET   A HG2  1 c 
ATOM   3876 H HG3  . MET   A 1 258 ? 30.303  -63.07  118.006 1   112.781 ? 952  MET   A HG3  1 c 
ATOM   3877 H HE1  . MET   A 1 258 ? 30.472  -65.966 119.488 1   145.969 ? 952  MET   A HE1  1 c 
ATOM   3878 H HE2  . MET   A 1 258 ? 31.826  -65.489 118.784 1   145.981 ? 952  MET   A HE2  1 c 
ATOM   3879 H HE3  . MET   A 1 258 ? 30.785  -64.42  119.354 1   145.489 ? 952  MET   A HE3  1 c 
ATOM   3880 N N    . ILE   A 1 259 ? 30.073  -60.23  114.804 1   127.973 ? 953  ILE   A N    1 ? 
ATOM   3881 C CA   . ILE   A 1 259 ? 30.148  -59.373 113.632 1   113.409 ? 953  ILE   A CA   1 ? 
ATOM   3882 C C    . ILE   A 1 259 ? 29.787  -60.143 112.366 1   112.436 ? 953  ILE   A C    1 ? 
ATOM   3883 O O    . ILE   A 1 259 ? 29.149  -59.584 111.485 1   126.912 ? 953  ILE   A O    1 ? 
ATOM   3884 C CB   . ILE   A 1 259 ? 31.538  -58.731 113.538 1   110.194 ? 953  ILE   A CB   1 ? 
ATOM   3885 C CG1  . ILE   A 1 259 ? 31.433  -57.241 113.756 1   105.166 ? 953  ILE   A CG1  1 ? 
ATOM   3886 C CG2  . ILE   A 1 259 ? 32.216  -59.068 112.208 1   118.336 ? 953  ILE   A CG2  1 ? 
ATOM   3887 C CD1  . ILE   A 1 259 ? 32.634  -56.647 114.461 1   109.351 ? 953  ILE   A CD1  1 ? 
ATOM   3888 H H    . ILE   A 1 259 ? 30.848  -60.445 115.238 1   121.749 ? 953  ILE   A H    1 c 
ATOM   3889 H HA   . ILE   A 1 259 ? 29.491  -58.659 113.744 1   115.251 ? 953  ILE   A HA   1 c 
ATOM   3890 H HB   . ILE   A 1 259 ? 32.09   -59.098 114.256 1   111.434 ? 953  ILE   A HB   1 c 
ATOM   3891 H HG12 . ILE   A 1 259 ? 31.326  -56.801 112.888 1   107.334 ? 953  ILE   A HG12 1 c 
ATOM   3892 H HG13 . ILE   A 1 259 ? 30.634  -57.051 114.289 1   107.368 ? 953  ILE   A HG13 1 c 
ATOM   3893 H HG21 . ILE   A 1 259 ? 33.036  -58.552 112.125 1   115.882 ? 953  ILE   A HG21 1 c 
ATOM   3894 H HG22 . ILE   A 1 259 ? 31.626  -58.845 111.469 1   115.917 ? 953  ILE   A HG22 1 c 
ATOM   3895 H HG23 . ILE   A 1 259 ? 32.431  -60.016 112.178 1   115.851 ? 953  ILE   A HG23 1 c 
ATOM   3896 H HD11 . ILE   A 1 259 ? 32.723  -57.046 115.347 1   108.072 ? 953  ILE   A HD11 1 c 
ATOM   3897 H HD12 . ILE   A 1 259 ? 32.518  -55.682 114.549 1   108.09  ? 953  ILE   A HD12 1 c 
ATOM   3898 H HD13 . ILE   A 1 259 ? 33.44   -56.83  113.942 1   108.09  ? 953  ILE   A HD13 1 c 
ATOM   3899 N N    . ASP   A 1 260 ? 30.22   -61.403 112.263 1   111.072 ? 954  ASP   A N    1 ? 
ATOM   3900 C CA   . ASP   A 1 260 ? 29.875  -62.254 111.136 1   103.576 ? 954  ASP   A CA   1 ? 
ATOM   3901 C C    . ASP   A 1 260 ? 28.46   -62.778 111.372 1   108.387 ? 954  ASP   A C    1 ? 
ATOM   3902 O O    . ASP   A 1 260 ? 28.233  -63.501 112.335 1   126.366 ? 954  ASP   A O    1 ? 
ATOM   3903 C CB   . ASP   A 1 260 ? 30.9    -63.364 110.973 1   104.442 ? 954  ASP   A CB   1 ? 
ATOM   3904 C CG   . ASP   A 1 260 ? 30.541  -64.415 109.945 1   112.389 ? 954  ASP   A CG   1 ? 
ATOM   3905 O OD1  . ASP   A 1 260 ? 29.883  -64.067 108.952 1   120.96  ? 954  ASP   A OD1  1 ? 
ATOM   3906 O OD2  . ASP   A 1 260 ? 30.953  -65.564 110.137 1   129.498 ? 954  ASP   A OD2  1 ? 
ATOM   3907 H H    . ASP   A 1 260 ? 30.755  -61.744 112.92  1   109.725 ? 954  ASP   A H    1 c 
ATOM   3908 H HA   . ASP   A 1 260 ? 29.883  -61.708 110.318 1   106.212 ? 954  ASP   A HA   1 c 
ATOM   3909 H HB2  . ASP   A 1 260 ? 31.758  -62.965 110.717 1   106.051 ? 954  ASP   A HB2  1 c 
ATOM   3910 H HB3  . ASP   A 1 260 ? 31.021  -63.811 111.837 1   106.176 ? 954  ASP   A HB3  1 c 
ATOM   3911 N N    . ALA   A 1 261 ? 27.509  -62.381 110.516 1   109.139 ? 955  ALA   A N    1 ? 
ATOM   3912 C CA   . ALA   A 1 261 ? 26.093  -62.655 110.73  1   114.848 ? 955  ALA   A CA   1 ? 
ATOM   3913 C C    . ALA   A 1 261 ? 25.786  -64.154 110.67  1   111.294 ? 955  ALA   A C    1 ? 
ATOM   3914 O O    . ALA   A 1 261 ? 24.92   -64.631 111.398 1   110.251 ? 955  ALA   A O    1 ? 
ATOM   3915 C CB   . ALA   A 1 261 ? 25.262  -61.903 109.717 1   128.083 ? 955  ALA   A CB   1 ? 
ATOM   3916 H H    . ALA   A 1 261 ? 27.755  -61.921 109.765 1   110.251 ? 955  ALA   A H    1 c 
ATOM   3917 H HA   . ALA   A 1 261 ? 25.855  -62.332 111.642 1   115.521 ? 955  ALA   A HA   1 c 
ATOM   3918 H HB1  . ALA   A 1 261 ? 25.435  -60.951 109.789 1   124.376 ? 955  ALA   A HB1  1 c 
ATOM   3919 H HB2  . ALA   A 1 261 ? 25.489  -62.203 108.821 1   124.072 ? 955  ALA   A HB2  1 c 
ATOM   3920 H HB3  . ALA   A 1 261 ? 24.318  -62.069 109.88  1   124.006 ? 955  ALA   A HB3  1 c 
ATOM   3921 N N    . ASP   A 1 262 ? 26.467  -64.892 109.785 1   116.746 ? 956  ASP   A N    1 ? 
ATOM   3922 C CA   . ASP   A 1 262 ? 26.239  -66.324 109.634 1   121.049 ? 956  ASP   A CA   1 ? 
ATOM   3923 C C    . ASP   A 1 262 ? 26.723  -67.083 110.862 1   112.093 ? 956  ASP   A C    1 ? 
ATOM   3924 O O    . ASP   A 1 262 ? 26.217  -68.15  111.166 1   102.112 ? 956  ASP   A O    1 ? 
ATOM   3925 C CB   . ASP   A 1 262 ? 26.903  -66.849 108.375 1   136.615 ? 956  ASP   A CB   1 ? 
ATOM   3926 C CG   . ASP   A 1 262 ? 26.23   -66.347 107.109 1   144.142 ? 956  ASP   A CG   1 ? 
ATOM   3927 O OD1  . ASP   A 1 262 ? 26.283  -65.124 106.88  1   156.188 ? 956  ASP   A OD1  1 ? 
ATOM   3928 O OD2  . ASP   A 1 262 ? 25.602  -67.164 106.406 1   134.922 ? 956  ASP   A OD2  1 ? 
ATOM   3929 H H    . ASP   A 1 262 ? 27.091  -64.489 109.253 1   116.555 ? 956  ASP   A H    1 c 
ATOM   3930 H HA   . ASP   A 1 262 ? 25.27   -66.471 109.54  1   121.216 ? 956  ASP   A HA   1 c 
ATOM   3931 H HB2  . ASP   A 1 262 ? 27.842  -66.568 108.363 1   134.385 ? 956  ASP   A HB2  1 c 
ATOM   3932 H HB3  . ASP   A 1 262 ? 26.874  -67.828 108.377 1   134.382 ? 956  ASP   A HB3  1 c 
ATOM   3933 N N    . SER   A 1 263 ? 27.723  -66.518 111.543 1   134.902 ? 957  SER   A N    1 ? 
ATOM   3934 C CA   . SER   A 1 263 ? 28.232  -67.033 112.806 1   130.702 ? 957  SER   A CA   1 ? 
ATOM   3935 C C    . SER   A 1 263 ? 27.178  -66.938 113.917 1   116.271 ? 957  SER   A C    1 ? 
ATOM   3936 O O    . SER   A 1 263 ? 27.128  -67.788 114.8   1   126.148 ? 957  SER   A O    1 ? 
ATOM   3937 C CB   . SER   A 1 263 ? 29.514  -66.313 113.18  1   130.876 ? 957  SER   A CB   1 ? 
ATOM   3938 O OG   . SER   A 1 263 ? 30.617  -66.827 112.443 1   133.204 ? 957  SER   A OG   1 ? 
ATOM   3939 H H    . SER   A 1 263 ? 28.121  -65.775 111.191 1   127.955 ? 957  SER   A H    1 c 
ATOM   3940 H HA   . SER   A 1 263 ? 28.446  -67.991 112.676 1   128.604 ? 957  SER   A HA   1 c 
ATOM   3941 H HB2  . SER   A 1 263 ? 29.419  -65.362 113     1   131.311 ? 957  SER   A HB2  1 c 
ATOM   3942 H HB3  . SER   A 1 263 ? 29.682  -66.427 114.135 1   131.287 ? 957  SER   A HB3  1 c 
ATOM   3943 H HG   . SER   A 1 263 ? 31.29   -66.429 112.641 0   132.3   ? 957  SER   A HG   1 c 
ATOM   3944 N N    . ARG   A 1 264 ? 26.323  -65.912 113.863 1   105.441 ? 958  ARG   A N    1 ? 
ATOM   3945 C CA   . ARG   A 1 264 ? 25.276  -65.7   114.852 1   89.261  ? 958  ARG   A CA   1 ? 
ATOM   3946 C C    . ARG   A 1 264 ? 24.287  -66.862 114.824 1   88.296  ? 958  ARG   A C    1 ? 
ATOM   3947 O O    . ARG   A 1 264 ? 24.068  -67.499 113.791 1   95.602  ? 958  ARG   A O    1 ? 
ATOM   3948 C CB   . ARG   A 1 264 ? 24.515  -64.386 114.619 1   87.668  ? 958  ARG   A CB   1 ? 
ATOM   3949 C CG   . ARG   A 1 264 ? 25.382  -63.137 114.606 1   97.736  ? 958  ARG   A CG   1 ? 
ATOM   3950 C CD   . ARG   A 1 264 ? 24.594  -61.906 114.195 1   102.39  ? 958  ARG   A CD   1 ? 
ATOM   3951 N NE   . ARG   A 1 264 ? 25.452  -60.782 113.797 1   102.013 ? 958  ARG   A NE   1 ? 
ATOM   3952 C CZ   . ARG   A 1 264 ? 25.052  -59.783 113.034 1   85.741  ? 958  ARG   A CZ   1 ? 
ATOM   3953 H H    . ARG   A 1 264 ? 26.396  -65.316 113.175 1   104.126 ? 958  ARG   A H    1 c 
ATOM   3954 H HA   . ARG   A 1 264 ? 25.703  -65.666 115.743 1   91.722  ? 958  ARG   A HA   1 c 
ATOM   3955 H HB2  . ARG   A 1 264 ? 24.042  -64.449 113.762 1   90.402  ? 958  ARG   A HB2  1 c 
ATOM   3956 H HB3  . ARG   A 1 264 ? 23.838  -64.287 115.32  1   90.255  ? 958  ARG   A HB3  1 c 
ATOM   3957 H HG2  . ARG   A 1 264 ? 25.757  -62.993 115.501 1   96.407  ? 958  ARG   A HG2  1 c 
ATOM   3958 H HG3  . ARG   A 1 264 ? 26.127  -63.262 113.98  1   96.601  ? 958  ARG   A HG3  1 c 
ATOM   3959 H HD2  . ARG   A 1 264 ? 24.009  -62.141 113.446 1   100.985 ? 958  ARG   A HD2  1 c 
ATOM   3960 H HD3  . ARG   A 1 264 ? 24.025  -61.628 114.939 1   101.192 ? 958  ARG   A HD3  1 c 
ATOM   3961 H HE   . ARG   A 1 264 ? 26.275  -60.771 114.081 1   98.054  ? 958  ARG   A HE   1 c 
ATOM   3962 N N    . PRO   A 1 265 ? 23.649  -67.152 115.977 1   93.356  ? 959  PRO   A N    1 ? 
ATOM   3963 C CA   . PRO   A 1 265 ? 22.722  -68.271 116.086 1   92.976  ? 959  PRO   A CA   1 ? 
ATOM   3964 C C    . PRO   A 1 265 ? 21.382  -68.026 115.415 1   86.227  ? 959  PRO   A C    1 ? 
ATOM   3965 O O    . PRO   A 1 265 ? 20.92   -66.897 115.377 1   88.336  ? 959  PRO   A O    1 ? 
ATOM   3966 C CB   . PRO   A 1 265 ? 22.508  -68.399 117.585 1   92.896  ? 959  PRO   A CB   1 ? 
ATOM   3967 C CG   . PRO   A 1 265 ? 22.761  -66.999 118.115 1   85.865  ? 959  PRO   A CG   1 ? 
ATOM   3968 C CD   . PRO   A 1 265 ? 23.799  -66.399 117.234 1   87.898  ? 959  PRO   A CD   1 ? 
ATOM   3969 H HA   . PRO   A 1 265 ? 23.136  -69.084 115.729 1   91.817  ? 959  PRO   A HA   1 c 
ATOM   3970 H HB2  . PRO   A 1 265 ? 21.596  -68.69  117.785 1   91.244  ? 959  PRO   A HB2  1 c 
ATOM   3971 H HB3  . PRO   A 1 265 ? 23.136  -69.038 117.973 1   91.269  ? 959  PRO   A HB3  1 c 
ATOM   3972 H HG2  . PRO   A 1 265 ? 21.941  -66.467 118.087 1   87.869  ? 959  PRO   A HG2  1 c 
ATOM   3973 H HG3  . PRO   A 1 265 ? 23.078  -67.034 119.04  1   87.869  ? 959  PRO   A HG3  1 c 
ATOM   3974 H HD2  . PRO   A 1 265 ? 23.634  -65.449 117.093 1   88.74   ? 959  PRO   A HD2  1 c 
ATOM   3975 H HD3  . PRO   A 1 265 ? 24.692  -66.52  117.604 1   88.708  ? 959  PRO   A HD3  1 c 
ATOM   3976 N N    . LYS   A 1 266 ? 20.752  -69.101 114.937 1   97.839  ? 960  LYS   A N    1 ? 
ATOM   3977 C CA   . LYS   A 1 266 ? 19.426  -69.034 114.334 1   108.832 ? 960  LYS   A CA   1 ? 
ATOM   3978 C C    . LYS   A 1 266 ? 18.342  -69.051 115.41  1   100.202 ? 960  LYS   A C    1 ? 
ATOM   3979 O O    . LYS   A 1 266 ? 18.522  -69.653 116.463 1   114.132 ? 960  LYS   A O    1 ? 
ATOM   3980 C CB   . LYS   A 1 266 ? 19.248  -70.193 113.35  1   110.74  ? 960  LYS   A CB   1 ? 
ATOM   3981 C CG   . LYS   A 1 266 ? 19.943  -69.934 112.008 1   122.163 ? 960  LYS   A CG   1 ? 
ATOM   3982 C CD   . LYS   A 1 266 ? 18.977  -69.535 110.896 1   131.883 ? 960  LYS   A CD   1 ? 
ATOM   3983 C CE   . LYS   A 1 266 ? 18.394  -70.76  110.241 1   143.767 ? 960  LYS   A CE   1 ? 
ATOM   3984 N NZ   . LYS   A 1 266 ? 16.931  -70.83  110.305 1   142.868 ? 960  LYS   A NZ   1 ? 
ATOM   3985 H H    . LYS   A 1 266 ? 21.165  -69.914 114.991 1   97.357  ? 960  LYS   A H    1 c 
ATOM   3986 H HA   . LYS   A 1 266 ? 19.357  -68.183 113.83  1   105.222 ? 960  LYS   A HA   1 c 
ATOM   3987 H HB2  . LYS   A 1 266 ? 19.615  -71.013 113.744 1   112.698 ? 960  LYS   A HB2  1 c 
ATOM   3988 H HB3  . LYS   A 1 266 ? 18.291  -70.336 113.19  1   112.911 ? 960  LYS   A HB3  1 c 
ATOM   3989 H HG2  . LYS   A 1 266 ? 20.604  -69.219 112.129 1   121.416 ? 960  LYS   A HG2  1 c 
ATOM   3990 H HG3  . LYS   A 1 266 ? 20.426  -70.747 111.742 1   121.778 ? 960  LYS   A HG3  1 c 
ATOM   3991 H HD2  . LYS   A 1 266 ? 18.252  -68.989 111.27  1   132.01  ? 960  LYS   A HD2  1 c 
ATOM   3992 H HD3  . LYS   A 1 266 ? 19.454  -69.003 110.223 1   132.175 ? 960  LYS   A HD3  1 c 
ATOM   3993 H HE2  . LYS   A 1 266 ? 18.661  -70.772 109.304 1   140.701 ? 960  LYS   A HE2  1 c 
ATOM   3994 H HE3  . LYS   A 1 266 ? 18.756  -71.562 110.658 1   140.491 ? 960  LYS   A HE3  1 c 
ATOM   3995 H HZ1  . LYS   A 1 266 ? 16.572  -70.099 109.908 1   143.144 ? 960  LYS   A HZ1  1 c 
ATOM   3996 H HZ2  . LYS   A 1 266 ? 16.664  -70.859 111.17  1   143.144 ? 960  LYS   A HZ2  1 c 
ATOM   3997 H HZ3  . LYS   A 1 266 ? 16.64   -71.574 109.878 1   143.144 ? 960  LYS   A HZ3  1 c 
ATOM   3998 N N    . PHE   A 1 267 ? 17.217  -68.383 115.116 1   97.685  ? 961  PHE   A N    1 ? 
ATOM   3999 C CA   . PHE   A 1 267 ? 16.091  -68.292 116.029 1   86.51   ? 961  PHE   A CA   1 ? 
ATOM   4000 C C    . PHE   A 1 267 ? 15.646  -69.692 116.424 1   84.843  ? 961  PHE   A C    1 ? 
ATOM   4001 O O    . PHE   A 1 267 ? 15.222  -69.925 117.549 1   86.962  ? 961  PHE   A O    1 ? 
ATOM   4002 C CB   . PHE   A 1 267 ? 14.91   -67.54  115.407 1   82.014  ? 961  PHE   A CB   1 ? 
ATOM   4003 C CG   . PHE   A 1 267 ? 15.091  -66.037 115.421 1   80.909  ? 961  PHE   A CG   1 ? 
ATOM   4004 C CD1  . PHE   A 1 267 ? 15.207  -65.366 116.623 1   92.38   ? 961  PHE   A CD1  1 ? 
ATOM   4005 C CD2  . PHE   A 1 267 ? 15.13   -65.299 114.254 1   86.548  ? 961  PHE   A CD2  1 ? 
ATOM   4006 C CE1  . PHE   A 1 267 ? 15.384  -63.994 116.666 1   102.411 ? 961  PHE   A CE1  1 ? 
ATOM   4007 C CE2  . PHE   A 1 267 ? 15.3    -63.925 114.297 1   92.419  ? 961  PHE   A CE2  1 ? 
ATOM   4008 C CZ   . PHE   A 1 267 ? 15.418  -63.272 115.5   1   93.991  ? 961  PHE   A CZ   1 ? 
ATOM   4009 H H    . PHE   A 1 267 ? 17.152  -67.967 114.305 1   95.561  ? 961  PHE   A H    1 c 
ATOM   4010 H HA   . PHE   A 1 267 ? 16.383  -67.81  116.845 1   87.491  ? 961  PHE   A HA   1 c 
ATOM   4011 H HB2  . PHE   A 1 267 ? 14.797  -67.842 114.478 1   82.889  ? 961  PHE   A HB2  1 c 
ATOM   4012 H HB3  . PHE   A 1 267 ? 14.094  -67.767 115.906 1   82.839  ? 961  PHE   A HB3  1 c 
ATOM   4013 H HD1  . PHE   A 1 267 ? 15.184  -65.857 117.43  1   91.661  ? 961  PHE   A HD1  1 c 
ATOM   4014 H HD2  . PHE   A 1 267 ? 15.05   -65.737 113.421 1   86.861  ? 961  PHE   A HD2  1 c 
ATOM   4015 H HE1  . PHE   A 1 267 ? 15.461  -63.554 117.497 1   97.743  ? 961  PHE   A HE1  1 c 
ATOM   4016 H HE2  . PHE   A 1 267 ? 15.327  -63.433 113.492 1   91.374  ? 961  PHE   A HE2  1 c 
ATOM   4017 H HZ   . PHE   A 1 267 ? 15.534  -62.335 115.524 1   95.434  ? 961  PHE   A HZ   1 c 
ATOM   4018 N N    . ARG   A 1 268 ? 15.731  -70.623 115.476 1   91.566  ? 962  ARG   A N    1 ? 
ATOM   4019 C CA   . ARG   A 1 268 ? 15.281  -71.978 115.741 1   95.28   ? 962  ARG   A CA   1 ? 
ATOM   4020 C C    . ARG   A 1 268 ? 16.216  -72.622 116.765 1   91.499  ? 962  ARG   A C    1 ? 
ATOM   4021 O O    . ARG   A 1 268 ? 15.793  -73.445 117.553 1   89.553  ? 962  ARG   A O    1 ? 
ATOM   4022 C CB   . ARG   A 1 268 ? 15.116  -72.784 114.449 1   103.974 ? 962  ARG   A CB   1 ? 
ATOM   4023 C CG   . ARG   A 1 268 ? 16.341  -73.57  114.004 1   108.999 ? 962  ARG   A CG   1 ? 
ATOM   4024 C CD   . ARG   A 1 268 ? 15.977  -74.681 113.042 1   109.624 ? 962  ARG   A CD   1 ? 
ATOM   4025 N NE   . ARG   A 1 268 ? 16.003  -76.022 113.638 1   110.984 ? 962  ARG   A NE   1 ? 
ATOM   4026 C CZ   . ARG   A 1 268 ? 17.099  -76.595 114.124 1   116.961 ? 962  ARG   A CZ   1 ? 
ATOM   4027 N NH1  . ARG   A 1 268 ? 17.052  -77.849 114.532 1   121.37  ? 962  ARG   A NH1  1 ? 
ATOM   4028 N NH2  . ARG   A 1 268 ? 18.245  -75.925 114.175 1   120.382 ? 962  ARG   A NH2  1 ? 
ATOM   4029 H H    . ARG   A 1 268 ? 16.057  -70.414 114.649 1   90.962  ? 962  ARG   A H    1 c 
ATOM   4030 H HA   . ARG   A 1 268 ? 14.382  -71.919 116.154 1   95.269  ? 962  ARG   A HA   1 c 
ATOM   4031 H HB2  . ARG   A 1 268 ? 14.371  -73.41  114.571 1   103.08  ? 962  ARG   A HB2  1 c 
ATOM   4032 H HB3  . ARG   A 1 268 ? 14.865  -72.167 113.729 1   102.889 ? 962  ARG   A HB3  1 c 
ATOM   4033 H HG2  . ARG   A 1 268 ? 16.976  -72.962 113.566 1   107.981 ? 962  ARG   A HG2  1 c 
ATOM   4034 H HG3  . ARG   A 1 268 ? 16.783  -73.958 114.788 1   107.985 ? 962  ARG   A HG3  1 c 
ATOM   4035 H HD2  . ARG   A 1 268 ? 15.081  -74.511 112.683 1   109.717 ? 962  ARG   A HD2  1 c 
ATOM   4036 H HD3  . ARG   A 1 268 ? 16.603  -74.657 112.289 1   109.783 ? 962  ARG   A HD3  1 c 
ATOM   4037 H HE   . ARG   A 1 268 ? 15.257  -76.467 113.677 1   112.181 ? 962  ARG   A HE   1 c 
ATOM   4038 H HH11 . ARG   A 1 268 ? 16.285  -78.288 114.529 1   119.854 ? 962  ARG   A HH11 1 c 
ATOM   4039 H HH12 . ARG   A 1 268 ? 17.791  -78.247 114.809 1   119.965 ? 962  ARG   A HH12 1 c 
ATOM   4040 H HH21 . ARG   A 1 268 ? 18.568  -75.546 113.442 1   119.259 ? 962  ARG   A HH21 1 c 
ATOM   4041 H HH22 . ARG   A 1 268 ? 18.684  -75.866 114.943 1   119.305 ? 962  ARG   A HH22 1 c 
ATOM   4042 N N    . GLU   A 1 269 ? 17.499  -72.261 116.736 1   105.653 ? 963  GLU   A N    1 ? 
ATOM   4043 C CA   . GLU   A 1 269 ? 18.47   -72.718 117.724 1   103.612 ? 963  GLU   A CA   1 ? 
ATOM   4044 C C    . GLU   A 1 269 ? 18.224  -72.057 119.074 1   91.888  ? 963  GLU   A C    1 ? 
ATOM   4045 O O    . GLU   A 1 269 ? 18.359  -72.692 120.111 1   94.575  ? 963  GLU   A O    1 ? 
ATOM   4046 C CB   . GLU   A 1 269 ? 19.901  -72.398 117.283 1   110.633 ? 963  GLU   A CB   1 ? 
ATOM   4047 C CG   . GLU   A 1 269 ? 20.473  -73.481 116.376 1   114.442 ? 963  GLU   A CG   1 ? 
ATOM   4048 C CD   . GLU   A 1 269 ? 21.485  -72.993 115.375 1   105.985 ? 963  GLU   A CD   1 ? 
ATOM   4049 O OE1  . GLU   A 1 269 ? 22.046  -71.883 115.514 1   97.988  ? 963  GLU   A OE1  1 ? 
ATOM   4050 O OE2  . GLU   A 1 269 ? 21.639  -73.752 114.409 1   113.316 ? 963  GLU   A OE2  1 ? 
ATOM   4051 H H    . GLU   A 1 269 ? 17.789  -71.719 116.06  1   101.627 ? 963  GLU   A H    1 c 
ATOM   4052 H HA   . GLU   A 1 269 ? 18.375  -73.699 117.828 1   102.923 ? 963  GLU   A HA   1 c 
ATOM   4053 H HB2  . GLU   A 1 269 ? 19.908  -71.538 116.816 1   109.689 ? 963  GLU   A HB2  1 c 
ATOM   4054 H HB3  . GLU   A 1 269 ? 20.469  -72.312 118.077 1   109.699 ? 963  GLU   A HB3  1 c 
ATOM   4055 H HG2  . GLU   A 1 269 ? 20.895  -74.17  116.932 1   111.546 ? 963  GLU   A HG2  1 c 
ATOM   4056 H HG3  . GLU   A 1 269 ? 19.736  -73.908 115.887 1   111.47  ? 963  GLU   A HG3  1 c 
ATOM   4057 N N    . LEU   A 1 270 ? 17.899  -70.766 119.049 1   90.86   ? 964  LEU   A N    1 ? 
ATOM   4058 C CA   . LEU   A 1 270 ? 17.62   -70.008 120.258 1   83.971  ? 964  LEU   A CA   1 ? 
ATOM   4059 C C    . LEU   A 1 270 ? 16.41   -70.566 121.004 1   86.775  ? 964  LEU   A C    1 ? 
ATOM   4060 O O    . LEU   A 1 270 ? 16.376  -70.578 122.226 1   96.089  ? 964  LEU   A O    1 ? 
ATOM   4061 C CB   . LEU   A 1 270 ? 17.394  -68.555 119.86  1   81.989  ? 964  LEU   A CB   1 ? 
ATOM   4062 C CG   . LEU   A 1 270 ? 18.649  -67.819 119.396 1   89.008  ? 964  LEU   A CG   1 ? 
ATOM   4063 C CD1  . LEU   A 1 270 ? 18.312  -66.546 118.64  1   99.82   ? 964  LEU   A CD1  1 ? 
ATOM   4064 C CD2  . LEU   A 1 270 ? 19.538  -67.508 120.582 1   88.999  ? 964  LEU   A CD2  1 ? 
ATOM   4065 H H    . LEU   A 1 270 ? 17.855  -70.335 118.243 1   89.559  ? 964  LEU   A H    1 c 
ATOM   4066 H HA   . LEU   A 1 270 ? 18.411  -70.066 120.85  1   85.455  ? 964  LEU   A HA   1 c 
ATOM   4067 H HB2  . LEU   A 1 270 ? 16.729  -68.531 119.134 1   84.135  ? 964  LEU   A HB2  1 c 
ATOM   4068 H HB3  . LEU   A 1 270 ? 17.018  -68.077 120.635 1   84.088  ? 964  LEU   A HB3  1 c 
ATOM   4069 H HG   . LEU   A 1 270 ? 19.151  -68.417 118.784 1   89.669  ? 964  LEU   A HG   1 c 
ATOM   4070 H HD11 . LEU   A 1 270 ? 18.131  -66.76  117.709 1   96.356  ? 964  LEU   A HD11 1 c 
ATOM   4071 H HD12 . LEU   A 1 270 ? 19.063  -65.928 118.688 1   96.338  ? 964  LEU   A HD12 1 c 
ATOM   4072 H HD13 . LEU   A 1 270 ? 17.527  -66.132 119.034 1   96.314  ? 964  LEU   A HD13 1 c 
ATOM   4073 H HD21 . LEU   A 1 270 ? 19.863  -68.336 120.972 1   88.959  ? 964  LEU   A HD21 1 c 
ATOM   4074 H HD22 . LEU   A 1 270 ? 19.032  -67.015 121.248 1   88.989  ? 964  LEU   A HD22 1 c 
ATOM   4075 H HD23 . LEU   A 1 270 ? 20.295  -66.972 120.29  1   89.038  ? 964  LEU   A HD23 1 c 
ATOM   4076 N N    . ILE   A 1 271 ? 15.398  -71.019 120.272 1   93.24   ? 965  ILE   A N    1 ? 
ATOM   4077 C CA   . ILE   A 1 271 ? 14.252  -71.655 120.898 1   90.303  ? 965  ILE   A CA   1 ? 
ATOM   4078 C C    . ILE   A 1 271 ? 14.731  -72.858 121.693 1   87.24   ? 965  ILE   A C    1 ? 
ATOM   4079 O O    . ILE   A 1 271 ? 14.335  -73.055 122.827 1   99.276  ? 965  ILE   A O    1 ? 
ATOM   4080 C CB   . ILE   A 1 271 ? 13.207  -72.079 119.858 1   89.601  ? 965  ILE   A CB   1 ? 
ATOM   4081 C CG1  . ILE   A 1 271 ? 12.777  -70.888 119.002 1   89.252  ? 965  ILE   A CG1  1 ? 
ATOM   4082 C CG2  . ILE   A 1 271 ? 12.02   -72.757 120.542 1   98.456  ? 965  ILE   A CG2  1 ? 
ATOM   4083 C CD1  . ILE   A 1 271 ? 11.763  -71.218 117.926 1   88.761  ? 965  ILE   A CD1  1 ? 
ATOM   4084 H H    . ILE   A 1 271 ? 15.426  -70.945 119.362 1   90.911  ? 965  ILE   A H    1 c 
ATOM   4085 H HA   . ILE   A 1 271 ? 13.838  -71.017 121.511 1   90.19   ? 965  ILE   A HA   1 c 
ATOM   4086 H HB   . ILE   A 1 271 ? 13.626  -72.735 119.265 1   91.252  ? 965  ILE   A HB   1 c 
ATOM   4087 H HG12 . ILE   A 1 271 ? 12.397  -70.204 119.589 1   89.263  ? 965  ILE   A HG12 1 c 
ATOM   4088 H HG13 . ILE   A 1 271 ? 13.566  -70.505 118.574 1   89.242  ? 965  ILE   A HG13 1 c 
ATOM   4089 H HG21 . ILE   A 1 271 ? 11.375  -73.043 119.874 1   95.662  ? 965  ILE   A HG21 1 c 
ATOM   4090 H HG22 . ILE   A 1 271 ? 11.594  -72.131 121.152 1   95.716  ? 965  ILE   A HG22 1 c 
ATOM   4091 H HG23 . ILE   A 1 271 ? 12.326  -73.533 121.04  1   95.691  ? 965  ILE   A HG23 1 c 
ATOM   4092 H HD11 . ILE   A 1 271 ? 12.053  -72.011 117.438 1   88.934  ? 965  ILE   A HD11 1 c 
ATOM   4093 H HD12 . ILE   A 1 271 ? 11.69   -70.467 117.308 1   88.966  ? 965  ILE   A HD12 1 c 
ATOM   4094 H HD13 . ILE   A 1 271 ? 10.893  -71.389 118.331 1   88.993  ? 965  ILE   A HD13 1 c 
ATOM   4095 N N    . ILE   A 1 272 ? 15.596  -73.658 121.079 1   96.662  ? 966  ILE   A N    1 ? 
ATOM   4096 C CA   . ILE   A 1 272 ? 16.074  -74.899 121.663 1   99.264  ? 966  ILE   A CA   1 ? 
ATOM   4097 C C    . ILE   A 1 272 ? 16.856  -74.608 122.939 1   93.046  ? 966  ILE   A C    1 ? 
ATOM   4098 O O    . ILE   A 1 272 ? 16.66   -75.288 123.933 1   90.633  ? 966  ILE   A O    1 ? 
ATOM   4099 C CB   . ILE   A 1 272 ? 16.951  -75.664 120.654 1   107.075 ? 966  ILE   A CB   1 ? 
ATOM   4100 C CG1  . ILE   A 1 272 ? 16.227  -75.827 119.318 1   114.305 ? 966  ILE   A CG1  1 ? 
ATOM   4101 C CG2  . ILE   A 1 272 ? 17.463  -76.985 121.23  1   99.697  ? 966  ILE   A CG2  1 ? 
ATOM   4102 C CD1  . ILE   A 1 272 ? 16.307  -77.209 118.701 1   120.713 ? 966  ILE   A CD1  1 ? 
ATOM   4103 H H    . ILE   A 1 272 ? 15.907  -73.417 120.254 1   95.018  ? 966  ILE   A H    1 c 
ATOM   4104 H HA   . ILE   A 1 272 ? 15.301  -75.454 121.887 1   98.884  ? 966  ILE   A HA   1 c 
ATOM   4105 H HB   . ILE   A 1 272 ? 17.735  -75.108 120.483 1   105.393 ? 966  ILE   A HB   1 c 
ATOM   4106 H HG12 . ILE   A 1 272 ? 15.283  -75.597 119.441 1   113.804 ? 966  ILE   A HG12 1 c 
ATOM   4107 H HG13 . ILE   A 1 272 ? 16.607  -75.187 118.685 1   113.795 ? 966  ILE   A HG13 1 c 
ATOM   4108 H HG21 . ILE   A 1 272 ? 18.143  -77.356 120.642 1   102.039 ? 966  ILE   A HG21 1 c 
ATOM   4109 H HG22 . ILE   A 1 272 ? 16.728  -77.613 121.309 1   102.045 ? 966  ILE   A HG22 1 c 
ATOM   4110 H HG23 . ILE   A 1 272 ? 17.851  -76.833 122.107 1   101.788 ? 966  ILE   A HG23 1 c 
ATOM   4111 H HD11 . ILE   A 1 272 ? 17.239  -77.459 118.559 1   118.483 ? 966  ILE   A HD11 1 c 
ATOM   4112 H HD12 . ILE   A 1 272 ? 15.842  -77.2   117.843 1   118.658 ? 966  ILE   A HD12 1 c 
ATOM   4113 H HD13 . ILE   A 1 272 ? 15.881  -77.861 119.289 1   118.47  ? 966  ILE   A HD13 1 c 
ATOM   4114 N N    . GLU   A 1 273 ? 17.786  -73.648 122.889 1   92.51   ? 967  GLU   A N    1 ? 
ATOM   4115 C CA   . GLU   A 1 273 ? 18.706  -73.414 123.99  1   97.358  ? 967  GLU   A CA   1 ? 
ATOM   4116 C C    . GLU   A 1 273 ? 17.953  -72.929 125.221 1   92.191  ? 967  GLU   A C    1 ? 
ATOM   4117 O O    . GLU   A 1 273 ? 18.198  -73.41  126.32  1   97.458  ? 967  GLU   A O    1 ? 
ATOM   4118 C CB   . GLU   A 1 273 ? 19.787  -72.408 123.595 1   98.654  ? 967  GLU   A CB   1 ? 
ATOM   4119 C CG   . GLU   A 1 273 ? 20.833  -72.993 122.653 1   108.662 ? 967  GLU   A CG   1 ? 
ATOM   4120 C CD   . GLU   A 1 273 ? 21.332  -74.369 123.06  1   113.044 ? 967  GLU   A CD   1 ? 
ATOM   4121 O OE1  . GLU   A 1 273 ? 21.132  -75.346 122.296 1   106.323 ? 967  GLU   A OE1  1 ? 
ATOM   4122 O OE2  . GLU   A 1 273 ? 21.887  -74.464 124.173 1   116.965 ? 967  GLU   A OE2  1 ? 
ATOM   4123 H H    . GLU   A 1 273 ? 17.852  -73.125 122.142 1   93.847  ? 967  GLU   A H    1 c 
ATOM   4124 H HA   . GLU   A 1 273 ? 19.138  -74.275 124.215 1   95.72   ? 967  GLU   A HA   1 c 
ATOM   4125 H HB2  . GLU   A 1 273 ? 19.361  -71.638 123.164 1   100.485 ? 967  GLU   A HB2  1 c 
ATOM   4126 H HB3  . GLU   A 1 273 ? 20.233  -72.087 124.406 1   100.486 ? 967  GLU   A HB3  1 c 
ATOM   4127 H HG2  . GLU   A 1 273 ? 20.453  -73.055 121.751 1   107.194 ? 967  GLU   A HG2  1 c 
ATOM   4128 H HG3  . GLU   A 1 273 ? 21.601  -72.384 122.61  1   107.254 ? 967  GLU   A HG3  1 c 
ATOM   4129 N N    . PHE   A 1 274 ? 17.071  -71.948 125.026 1   87.264  ? 968  PHE   A N    1 ? 
ATOM   4130 C CA   . PHE   A 1 274 ? 16.353  -71.336 126.122 1   85.339  ? 968  PHE   A CA   1 ? 
ATOM   4131 C C    . PHE   A 1 274 ? 15.375  -72.321 126.753 1   87.245  ? 968  PHE   A C    1 ? 
ATOM   4132 O O    . PHE   A 1 274 ? 15.146  -72.248 127.958 1   92.975  ? 968  PHE   A O    1 ? 
ATOM   4133 C CB   . PHE   A 1 274 ? 15.652  -70.069 125.639 1   90.842  ? 968  PHE   A CB   1 ? 
ATOM   4134 C CG   . PHE   A 1 274 ? 16.571  -68.867 125.703 1   88.302  ? 968  PHE   A CG   1 ? 
ATOM   4135 C CD1  . PHE   A 1 274 ? 16.991  -68.362 126.924 1   95.641  ? 968  PHE   A CD1  1 ? 
ATOM   4136 C CD2  . PHE   A 1 274 ? 17.01   -68.25  124.55  1   85.309  ? 968  PHE   A CD2  1 ? 
ATOM   4137 C CE1  . PHE   A 1 274 ? 17.833  -67.268 126.989 1   90.133  ? 968  PHE   A CE1  1 ? 
ATOM   4138 C CE2  . PHE   A 1 274 ? 17.847  -67.152 124.627 1   89.271  ? 968  PHE   A CE2  1 ? 
ATOM   4139 C CZ   . PHE   A 1 274 ? 18.264  -66.669 125.845 1   83.009  ? 968  PHE   A CZ   1 ? 
ATOM   4140 H H    . PHE   A 1 274 ? 16.917  -71.648 124.176 1   88.083  ? 968  PHE   A H    1 c 
ATOM   4141 H HA   . PHE   A 1 274 ? 17.017  -71.078 126.815 1   87.168  ? 968  PHE   A HA   1 c 
ATOM   4142 H HB2  . PHE   A 1 274 ? 15.35   -70.201 124.713 1   88.993  ? 968  PHE   A HB2  1 c 
ATOM   4143 H HB3  . PHE   A 1 274 ? 14.866  -69.904 126.206 1   89.109  ? 968  PHE   A HB3  1 c 
ATOM   4144 H HD1  . PHE   A 1 274 ? 16.702  -68.777 127.72  1   92.413  ? 968  PHE   A HD1  1 c 
ATOM   4145 H HD2  . PHE   A 1 274 ? 16.734  -68.574 123.709 1   87.045  ? 968  PHE   A HD2  1 c 
ATOM   4146 H HE1  . PHE   A 1 274 ? 18.112  -66.938 127.829 1   89.584  ? 968  PHE   A HE1  1 c 
ATOM   4147 H HE2  . PHE   A 1 274 ? 18.144  -66.737 123.833 1   86.912  ? 968  PHE   A HE2  1 c 
ATOM   4148 H HZ   . PHE   A 1 274 ? 18.834  -65.918 125.887 1   86.166  ? 968  PHE   A HZ   1 c 
ATOM   4149 N N    . SER   A 1 275 ? 14.792  -73.212 125.944 1   83.218  ? 969  SER   A N    1 ? 
ATOM   4150 C CA   . SER   A 1 275 ? 13.87   -74.223 126.438 1   94.82   ? 969  SER   A CA   1 ? 
ATOM   4151 C C    . SER   A 1 275 ? 14.579  -75.194 127.368 1   92.331  ? 969  SER   A C    1 ? 
ATOM   4152 O O    . SER   A 1 275 ? 14.02   -75.613 128.373 1   101.339 ? 969  SER   A O    1 ? 
ATOM   4153 C CB   . SER   A 1 275 ? 13.244  -74.984 125.315 1   100.23  ? 969  SER   A CB   1 ? 
ATOM   4154 O OG   . SER   A 1 275 ? 12.771  -74.08  124.336 1   103.051 ? 969  SER   A OG   1 ? 
ATOM   4155 H H    . SER   A 1 275 ? 14.97   -73.184 125.048 1   86.756  ? 969  SER   A H    1 c 
ATOM   4156 H HA   . SER   A 1 275 ? 13.154  -73.767 126.949 1   92.951  ? 969  SER   A HA   1 c 
ATOM   4157 H HB2  . SER   A 1 275 ? 13.903  -75.584 124.917 1   99.581  ? 969  SER   A HB2  1 c 
ATOM   4158 H HB3  . SER   A 1 275 ? 12.502  -75.518 125.656 1   99.614  ? 969  SER   A HB3  1 c 
ATOM   4159 H HG   . SER   A 1 275 ? 12.425  -74.512 123.706 0   103.91  ? 969  SER   A HG   1 c 
ATOM   4160 N N    . LYS   A 1 276 ? 15.786  -75.602 126.983 1   96.592  ? 970  LYS   A N    1 ? 
ATOM   4161 C CA   . LYS   A 1 276 ? 16.572  -76.495 127.812 1   97.345  ? 970  LYS   A CA   1 ? 
ATOM   4162 C C    . LYS   A 1 276 ? 16.772  -75.822 129.162 1   87.682  ? 970  LYS   A C    1 ? 
ATOM   4163 O O    . LYS   A 1 276 ? 16.634  -76.43  130.21  1   92.236  ? 970  LYS   A O    1 ? 
ATOM   4164 C CB   . LYS   A 1 276 ? 17.942  -76.749 127.18  1   100.668 ? 970  LYS   A CB   1 ? 
ATOM   4165 C CG   . LYS   A 1 276 ? 18.016  -77.792 126.086 1   95.365  ? 970  LYS   A CG   1 ? 
ATOM   4166 C CD   . LYS   A 1 276 ? 19.124  -77.435 125.101 1   99.979  ? 970  LYS   A CD   1 ? 
ATOM   4167 C CE   . LYS   A 1 276 ? 19.755  -78.644 124.479 1   103.729 ? 970  LYS   A CE   1 ? 
ATOM   4168 N NZ   . LYS   A 1 276 ? 20.832  -78.265 123.559 1   106.593 ? 970  LYS   A NZ   1 ? 
ATOM   4169 H H    . LYS   A 1 276 ? 16.126  -75.325 126.181 1   95.684  ? 970  LYS   A H    1 c 
ATOM   4170 H HA   . LYS   A 1 276 ? 16.077  -77.345 127.933 1   95.931  ? 970  LYS   A HA   1 c 
ATOM   4171 H HB2  . LYS   A 1 276 ? 18.268  -75.9   126.814 1   98.637  ? 970  LYS   A HB2  1 c 
ATOM   4172 H HB3  . LYS   A 1 276 ? 18.562  -77.015 127.892 1   98.589  ? 970  LYS   A HB3  1 c 
ATOM   4173 H HG2  . LYS   A 1 276 ? 18.198  -78.669 126.487 1   97.659  ? 970  LYS   A HG2  1 c 
ATOM   4174 H HG3  . LYS   A 1 276 ? 17.155  -77.83  125.616 1   97.602  ? 970  LYS   A HG3  1 c 
ATOM   4175 H HD2  . LYS   A 1 276 ? 18.751  -76.869 124.391 1   99.711  ? 970  LYS   A HD2  1 c 
ATOM   4176 H HD3  . LYS   A 1 276 ? 19.818  -76.919 125.567 1   99.752  ? 970  LYS   A HD3  1 c 
ATOM   4177 H HE2  . LYS   A 1 276 ? 20.119  -79.219 125.176 1   103.486 ? 970  LYS   A HE2  1 c 
ATOM   4178 H HE3  . LYS   A 1 276 ? 19.081  -79.148 123.989 1   103.517 ? 970  LYS   A HE3  1 c 
ATOM   4179 H HZ1  . LYS   A 1 276 ? 21.477  -77.817 124.011 1   105.703 ? 970  LYS   A HZ1  1 c 
ATOM   4180 H HZ2  . LYS   A 1 276 ? 20.503  -77.733 122.904 1   105.703 ? 970  LYS   A HZ2  1 c 
ATOM   4181 H HZ3  . LYS   A 1 276 ? 21.192  -79.009 123.187 1   105.703 ? 970  LYS   A HZ3  1 c 
ATOM   4182 N N    . MET   A 1 277 ? 17.088  -74.536 129.107 1   86.525  ? 971  MET   A N    1 ? 
ATOM   4183 C CA   . MET   A 1 277 ? 17.332  -73.745 130.292 1   86.294  ? 971  MET   A CA   1 ? 
ATOM   4184 C C    . MET   A 1 277 ? 16.047  -73.568 131.094 1   87.939  ? 971  MET   A C    1 ? 
ATOM   4185 O O    . MET   A 1 277 ? 16.076  -73.591 132.321 1   96.078  ? 971  MET   A O    1 ? 
ATOM   4186 C CB   . MET   A 1 277 ? 17.908  -72.391 129.884 1   88.507  ? 971  MET   A CB   1 ? 
ATOM   4187 C CG   . MET   A 1 277 ? 19.264  -72.513 129.225 1   90.749  ? 971  MET   A CG   1 ? 
ATOM   4188 S SD   . MET   A 1 277 ? 20.005  -70.9   128.918 1   96.526  ? 971  MET   A SD   1 ? 
ATOM   4189 C CE   . MET   A 1 277 ? 21.712  -71.449 128.953 1   106.153 ? 971  MET   A CE   1 ? 
ATOM   4190 H H    . MET   A 1 277 ? 17.157  -74.131 128.291 1   86.987  ? 971  MET   A H    1 c 
ATOM   4191 H HA   . MET   A 1 277 ? 17.986  -74.226 130.849 1   87.057  ? 971  MET   A HA   1 c 
ATOM   4192 H HB2  . MET   A 1 277 ? 17.286  -71.954 129.265 1   88.52   ? 971  MET   A HB2  1 c 
ATOM   4193 H HB3  . MET   A 1 277 ? 17.987  -71.827 130.682 1   88.505  ? 971  MET   A HB3  1 c 
ATOM   4194 H HG2  . MET   A 1 277 ? 19.86   -73.031 129.801 1   91.422  ? 971  MET   A HG2  1 c 
ATOM   4195 H HG3  . MET   A 1 277 ? 19.176  -72.987 128.378 1   91.287  ? 971  MET   A HG3  1 c 
ATOM   4196 H HE1  . MET   A 1 277 ? 22.3    -70.688 128.794 1   103.497 ? 971  MET   A HE1  1 c 
ATOM   4197 H HE2  . MET   A 1 277 ? 21.911  -71.837 129.824 1   103.411 ? 971  MET   A HE2  1 c 
ATOM   4198 H HE3  . MET   A 1 277 ? 21.851  -72.119 128.259 1   103.575 ? 971  MET   A HE3  1 c 
ATOM   4199 N N    . ALA   A 1 278 ? 14.925  -73.383 130.395 1   95.948  ? 972  ALA   A N    1 ? 
ATOM   4200 C CA   . ALA   A 1 278 ? 13.628  -73.228 131.032 1   92.386  ? 972  ALA   A CA   1 ? 
ATOM   4201 C C    . ALA   A 1 278 ? 13.243  -74.489 131.801 1   87.148  ? 972  ALA   A C    1 ? 
ATOM   4202 O O    . ALA   A 1 278 ? 12.447  -74.412 132.723 1   101.723 ? 972  ALA   A O    1 ? 
ATOM   4203 C CB   . ALA   A 1 278 ? 12.597  -72.913 129.983 1   104.829 ? 972  ALA   A CB   1 ? 
ATOM   4204 H H    . ALA   A 1 278 ? 14.972  -73.339 129.484 1   93.121  ? 972  ALA   A H    1 c 
ATOM   4205 H HA   . ALA   A 1 278 ? 13.684  -72.471 131.678 1   94.251  ? 972  ALA   A HA   1 c 
ATOM   4206 H HB1  . ALA   A 1 278 ? 12.85   -72.103 129.509 1   100.951 ? 972  ALA   A HB1  1 c 
ATOM   4207 H HB2  . ALA   A 1 278 ? 12.537  -73.648 129.351 1   100.953 ? 972  ALA   A HB2  1 c 
ATOM   4208 H HB3  . ALA   A 1 278 ? 11.731  -72.78  130.404 1   100.951 ? 972  ALA   A HB3  1 c 
ATOM   4209 N N    . ARG   A 1 279 ? 13.781  -75.644 131.388 1   96.065  ? 973  ARG   A N    1 ? 
ATOM   4210 C CA   . ARG   A 1 279 ? 13.566  -76.927 132.045 1   95.765  ? 973  ARG   A CA   1 ? 
ATOM   4211 C C    . ARG   A 1 279 ? 14.106  -76.888 133.476 1   100.389 ? 973  ARG   A C    1 ? 
ATOM   4212 O O    . ARG   A 1 279 ? 13.502  -77.487 134.356 1   110.86  ? 973  ARG   A O    1 ? 
ATOM   4213 C CB   . ARG   A 1 279 ? 14.289  -78.062 131.304 1   99.399  ? 973  ARG   A CB   1 ? 
ATOM   4214 C CG   . ARG   A 1 279 ? 13.468  -79.285 130.93  1   106.254 ? 973  ARG   A CG   1 ? 
ATOM   4215 C CD   . ARG   A 1 279 ? 13.2    -79.25  129.439 1   128.341 ? 973  ARG   A CD   1 ? 
ATOM   4216 N NE   . ARG   A 1 279 ? 11.999  -79.978 129.021 1   135.416 ? 973  ARG   A NE   1 ? 
ATOM   4217 C CZ   . ARG   A 1 279 ? 11.358  -79.771 127.866 1   159.431 ? 973  ARG   A CZ   1 ? 
ATOM   4218 N NH1  . ARG   A 1 279 ? 10.276  -80.476 127.587 1   154.02  ? 973  ARG   A NH1  1 ? 
ATOM   4219 N NH2  . ARG   A 1 279 ? 11.775  -78.867 126.984 1   164.516 ? 973  ARG   A NH2  1 ? 
ATOM   4220 H H    . ARG   A 1 279 ? 14.301  -75.631 130.636 1   93.83   ? 973  ARG   A H    1 c 
ATOM   4221 H HA   . ARG   A 1 279 ? 12.592  -77.108 132.071 1   97.378  ? 973  ARG   A HA   1 c 
ATOM   4222 H HB2  . ARG   A 1 279 ? 14.675  -77.693 130.483 1   100.285 ? 973  ARG   A HB2  1 c 
ATOM   4223 H HB3  . ARG   A 1 279 ? 15.038  -78.36  131.863 1   100.127 ? 973  ARG   A HB3  1 c 
ATOM   4224 H HG2  . ARG   A 1 279 ? 13.964  -80.102 131.156 1   109.249 ? 973  ARG   A HG2  1 c 
ATOM   4225 H HG3  . ARG   A 1 279 ? 12.616  -79.28  131.418 1   109.178 ? 973  ARG   A HG3  1 c 
ATOM   4226 H HD2  . ARG   A 1 279 ? 13.114  -78.316 129.158 1   124.463 ? 973  ARG   A HD2  1 c 
ATOM   4227 H HD3  . ARG   A 1 279 ? 13.976  -79.626 128.976 1   124.485 ? 973  ARG   A HD3  1 c 
ATOM   4228 H HE   . ARG   A 1 279 ? 11.682  -80.586 129.559 1   138.884 ? 973  ARG   A HE   1 c 
ATOM   4229 H HH11 . ARG   A 1 279 ? 10.331  -81.356 127.512 1   155.664 ? 973  ARG   A HH11 1 c 
ATOM   4230 H HH12 . ARG   A 1 279 ? 9.501   -80.065 127.476 1   155.661 ? 973  ARG   A HH12 1 c 
ATOM   4231 H HH21 . ARG   A 1 279 ? 12.639  -78.751 126.841 1   162.692 ? 973  ARG   A HH21 1 c 
ATOM   4232 H HH22 . ARG   A 1 279 ? 11.181  -78.384 126.541 1   162.877 ? 973  ARG   A HH22 1 c 
ATOM   4233 N N    . ASP   A 1 280 ? 15.261  -76.227 133.692 1   104.426 ? 974  ASP   A N    1 ? 
ATOM   4234 C CA   . ASP   A 1 280 ? 15.874  -76.091 135.011 1   99.875  ? 974  ASP   A CA   1 ? 
ATOM   4235 C C    . ASP   A 1 280 ? 16.349  -74.654 135.212 1   90.779  ? 974  ASP   A C    1 ? 
ATOM   4236 O O    . ASP   A 1 280 ? 17.531  -74.354 135.127 1   102.321 ? 974  ASP   A O    1 ? 
ATOM   4237 C CB   . ASP   A 1 280 ? 17.017  -77.067 135.215 1   105.246 ? 974  ASP   A CB   1 ? 
ATOM   4238 C CG   . ASP   A 1 280 ? 17.644  -77.045 136.597 1   102.955 ? 974  ASP   A CG   1 ? 
ATOM   4239 O OD1  . ASP   A 1 280 ? 17.052  -76.425 137.51  1   103.972 ? 974  ASP   A OD1  1 ? 
ATOM   4240 O OD2  . ASP   A 1 280 ? 18.726  -77.638 136.727 1   103.358 ? 974  ASP   A OD2  1 ? 
ATOM   4241 H H    . ASP   A 1 280 ? 15.688  -75.85  132.978 1   102.246 ? 974  ASP   A H    1 c 
ATOM   4242 H HA   . ASP   A 1 280 ? 15.197  -76.298 135.692 1   99.931  ? 974  ASP   A HA   1 c 
ATOM   4243 H HB2  . ASP   A 1 280 ? 16.685  -77.973 135.048 1   103.465 ? 974  ASP   A HB2  1 c 
ATOM   4244 H HB3  . ASP   A 1 280 ? 17.718  -76.88  134.556 1   103.464 ? 974  ASP   A HB3  1 c 
ATOM   4245 N N    . PRO   A 1 281 ? 15.41   -73.716 135.423 1   88.803  ? 975  PRO   A N    1 ? 
ATOM   4246 C CA   . PRO   A 1 281 ? 15.696  -72.286 135.346 1   93.085  ? 975  PRO   A CA   1 ? 
ATOM   4247 C C    . PRO   A 1 281 ? 16.718  -71.734 136.334 1   94.035  ? 975  PRO   A C    1 ? 
ATOM   4248 O O    . PRO   A 1 281 ? 17.446  -70.811 136     1   88.321  ? 975  PRO   A O    1 ? 
ATOM   4249 C CB   . PRO   A 1 281 ? 14.342  -71.622 135.564 1   90.671  ? 975  PRO   A CB   1 ? 
ATOM   4250 C CG   . PRO   A 1 281 ? 13.407  -72.728 136.015 1   90.303  ? 975  PRO   A CG   1 ? 
ATOM   4251 C CD   . PRO   A 1 281 ? 13.978  -74.016 135.541 1   90.924  ? 975  PRO   A CD   1 ? 
ATOM   4252 H HA   . PRO   A 1 281 ? 15.998  -72.077 134.438 1   91.983  ? 975  PRO   A HA   1 c 
ATOM   4253 H HB2  . PRO   A 1 281 ? 14.403  -70.926 136.246 1   91.253  ? 975  PRO   A HB2  1 c 
ATOM   4254 H HB3  . PRO   A 1 281 ? 14.019  -71.215 134.737 1   91.188  ? 975  PRO   A HB3  1 c 
ATOM   4255 H HG2  . PRO   A 1 281 ? 13.33   -72.733 136.99  1   90.575  ? 975  PRO   A HG2  1 c 
ATOM   4256 H HG3  . PRO   A 1 281 ? 12.517  -72.596 135.637 1   90.763  ? 975  PRO   A HG3  1 c 
ATOM   4257 H HD2  . PRO   A 1 281 ? 13.823  -74.729 136.189 1   90.434  ? 975  PRO   A HD2  1 c 
ATOM   4258 H HD3  . PRO   A 1 281 ? 13.607  -74.276 134.68  1   90.472  ? 975  PRO   A HD3  1 c 
ATOM   4259 N N    . GLN   A 1 282 ? 16.75   -72.271 137.559 1   104.756 ? 976  GLN   A N    1 ? 
ATOM   4260 C CA   . GLN   A 1 282 ? 17.592  -71.715 138.608 1   105.906 ? 976  GLN   A CA   1 ? 
ATOM   4261 C C    . GLN   A 1 282 ? 19.074  -71.963 138.329 1   98.166  ? 976  GLN   A C    1 ? 
ATOM   4262 O O    . GLN   A 1 282 ? 19.924  -71.24  138.85  1   100.559 ? 976  GLN   A O    1 ? 
ATOM   4263 C CB   . GLN   A 1 282 ? 17.134  -72.269 139.948 1   117.482 ? 976  GLN   A CB   1 ? 
ATOM   4264 C CG   . GLN   A 1 282 ? 15.633  -72.083 140.136 1   119.11  ? 976  GLN   A CG   1 ? 
ATOM   4265 C CD   . GLN   A 1 282 ? 15.231  -71.848 141.567 1   126.889 ? 976  GLN   A CD   1 ? 
ATOM   4266 O OE1  . GLN   A 1 282 ? 14.794  -70.758 141.931 1   133.708 ? 976  GLN   A OE1  1 ? 
ATOM   4267 N NE2  . GLN   A 1 282 ? 15.341  -72.876 142.393 1   153.257 ? 976  GLN   A NE2  1 ? 
ATOM   4268 H H    . GLN   A 1 282 ? 16.243  -73.009 137.741 1   102.501 ? 976  GLN   A H    1 c 
ATOM   4269 H HA   . GLN   A 1 282 ? 17.445  -70.735 138.627 1   106.076 ? 976  GLN   A HA   1 c 
ATOM   4270 H HB2  . GLN   A 1 282 ? 17.352  -73.223 139.996 1   115.104 ? 976  GLN   A HB2  1 c 
ATOM   4271 H HB3  . GLN   A 1 282 ? 17.613  -71.81  140.669 1   115.155 ? 976  GLN   A HB3  1 c 
ATOM   4272 H HG2  . GLN   A 1 282 ? 15.33   -71.322 139.598 1   120.363 ? 976  GLN   A HG2  1 c 
ATOM   4273 H HG3  . GLN   A 1 282 ? 15.167  -72.882 139.81  1   120.339 ? 976  GLN   A HG3  1 c 
ATOM   4274 H HE21 . GLN   A 1 282 ? 15.024  -72.815 143.22  1   144.448 ? 976  GLN   A HE21 1 c 
ATOM   4275 H HE22 . GLN   A 1 282 ? 15.732  -73.625 142.121 1   144.359 ? 976  GLN   A HE22 1 c 
ATOM   4276 N N    . ARG   A 1 283 ? 19.371  -72.982 137.51  1   98.837  ? 977  ARG   A N    1 ? 
ATOM   4277 C CA   . ARG   A 1 283 ? 20.727  -73.282 137.064 1   94.423  ? 977  ARG   A CA   1 ? 
ATOM   4278 C C    . ARG   A 1 283 ? 21.271  -72.177 136.156 1   90.913  ? 977  ARG   A C    1 ? 
ATOM   4279 O O    . ARG   A 1 283 ? 22.468  -71.927 136.146 1   91.723  ? 977  ARG   A O    1 ? 
ATOM   4280 C CB   . ARG   A 1 283 ? 20.741  -74.63  136.337 1   96.138  ? 977  ARG   A CB   1 ? 
ATOM   4281 C CG   . ARG   A 1 283 ? 22.11   -75.148 135.92  1   98.755  ? 977  ARG   A CG   1 ? 
ATOM   4282 C CD   . ARG   A 1 283 ? 21.946  -76.558 135.394 1   105.132 ? 977  ARG   A CD   1 ? 
ATOM   4283 N NE   . ARG   A 1 283 ? 23.14   -77.113 134.751 1   107.746 ? 977  ARG   A NE   1 ? 
ATOM   4284 C CZ   . ARG   A 1 283 ? 23.235  -78.352 134.261 1   113.419 ? 977  ARG   A CZ   1 ? 
ATOM   4285 N NH1  . ARG   A 1 283 ? 22.198  -79.169 134.248 1   126.438 ? 977  ARG   A NH1  1 ? 
ATOM   4286 N NH2  . ARG   A 1 283 ? 24.383  -78.802 133.797 1   119.915 ? 977  ARG   A NH2  1 ? 
ATOM   4287 H H    . ARG   A 1 283 ? 18.695  -73.528 137.227 1   97.737  ? 977  ARG   A H    1 c 
ATOM   4288 H HA   . ARG   A 1 283 ? 21.308  -73.348 137.863 1   94.948  ? 977  ARG   A HA   1 c 
ATOM   4289 H HB2  . ARG   A 1 283 ? 20.322  -75.298 136.921 1   96.398  ? 977  ARG   A HB2  1 c 
ATOM   4290 H HB3  . ARG   A 1 283 ? 20.183  -74.552 135.534 1   96.423  ? 977  ARG   A HB3  1 c 
ATOM   4291 H HG2  . ARG   A 1 283 ? 22.484  -74.577 135.214 1   99.571  ? 977  ARG   A HG2  1 c 
ATOM   4292 H HG3  . ARG   A 1 283 ? 22.717  -75.152 136.692 1   99.569  ? 977  ARG   A HG3  1 c 
ATOM   4293 H HD2  . ARG   A 1 283 ? 21.69   -77.137 136.141 1   104.35  ? 977  ARG   A HD2  1 c 
ATOM   4294 H HD3  . ARG   A 1 283 ? 21.208  -76.564 134.75  1   104.27  ? 977  ARG   A HD3  1 c 
ATOM   4295 H HE   . ARG   A 1 283 ? 23.84   -76.598 134.683 1   108.529 ? 977  ARG   A HE   1 c 
ATOM   4296 H HH11 . ARG   A 1 283 ? 21.431  -78.924 134.611 1   121.716 ? 977  ARG   A HH11 1 c 
ATOM   4297 H HH12 . ARG   A 1 283 ? 22.271  -79.967 133.875 1   122.09  ? 977  ARG   A HH12 1 c 
ATOM   4298 H HH21 . ARG   A 1 283 ? 25.117  -78.32  133.898 1   117.737 ? 977  ARG   A HH21 1 c 
ATOM   4299 H HH22 . ARG   A 1 283 ? 24.419  -79.584 133.384 1   117.939 ? 977  ARG   A HH22 1 c 
ATOM   4300 N N    . TYR   A 1 284 ? 20.407  -71.52  135.373 1   91.326  ? 978  TYR   A N    1 ? 
ATOM   4301 C CA   . TYR   A 1 284 ? 20.88   -70.564 134.378 1   88.572  ? 978  TYR   A CA   1 ? 
ATOM   4302 C C    . TYR   A 1 284 ? 20.659  -69.097 134.763 1   89.597  ? 978  TYR   A C    1 ? 
ATOM   4303 O O    . TYR   A 1 284 ? 21.366  -68.223 134.251 1   84.632  ? 978  TYR   A O    1 ? 
ATOM   4304 C CB   . TYR   A 1 284 ? 20.241  -70.927 133.043 1   86.62   ? 978  TYR   A CB   1 ? 
ATOM   4305 C CG   . TYR   A 1 284 ? 20.581  -72.357 132.674 1   82.98   ? 978  TYR   A CG   1 ? 
ATOM   4306 C CD1  . TYR   A 1 284 ? 21.875  -72.708 132.344 1   83.898  ? 978  TYR   A CD1  1 ? 
ATOM   4307 C CD2  . TYR   A 1 284 ? 19.622  -73.355 132.708 1   87.531  ? 978  TYR   A CD2  1 ? 
ATOM   4308 C CE1  . TYR   A 1 284 ? 22.198  -74.005 131.996 1   89.804  ? 978  TYR   A CE1  1 ? 
ATOM   4309 C CE2  . TYR   A 1 284 ? 19.934  -74.661 132.378 1   85.864  ? 978  TYR   A CE2  1 ? 
ATOM   4310 C CZ   . TYR   A 1 284 ? 21.226  -74.986 132.02  1   85.893  ? 978  TYR   A CZ   1 ? 
ATOM   4311 O OH   . TYR   A 1 284 ? 21.55   -76.266 131.697 1   94.349  ? 978  TYR   A OH   1 ? 
ATOM   4312 H H    . TYR   A 1 284 ? 19.51   -71.676 135.448 1   90.745  ? 978  TYR   A H    1 c 
ATOM   4313 H HA   . TYR   A 1 284 ? 21.86   -70.696 134.279 1   88.916  ? 978  TYR   A HA   1 c 
ATOM   4314 H HB2  . TYR   A 1 284 ? 19.266  -70.829 133.114 1   86.248  ? 978  TYR   A HB2  1 c 
ATOM   4315 H HB3  . TYR   A 1 284 ? 20.578  -70.321 132.348 1   86.37   ? 978  TYR   A HB3  1 c 
ATOM   4316 H HD1  . TYR   A 1 284 ? 22.543  -72.041 132.312 1   85.089  ? 978  TYR   A HD1  1 c 
ATOM   4317 H HD2  . TYR   A 1 284 ? 18.734  -73.137 132.943 1   86.091  ? 978  TYR   A HD2  1 c 
ATOM   4318 H HE1  . TYR   A 1 284 ? 23.083  -74.225 131.76  1   87.476  ? 978  TYR   A HE1  1 c 
ATOM   4319 H HE2  . TYR   A 1 284 ? 19.267  -75.326 132.393 1   86.303  ? 978  TYR   A HE2  1 c 
ATOM   4320 H HH   . TYR   A 1 284 ? 22.39   -76.314 131.515 0   95.21   ? 978  TYR   A HH   1 c 
ATOM   4321 N N    . LEU   A 1 285 ? 19.708  -68.804 135.656 1   91.682  ? 979  LEU   A N    1 ? 
ATOM   4322 C CA   . LEU   A 1 285 ? 19.564  -67.45  136.165 1   95.009  ? 979  LEU   A CA   1 ? 
ATOM   4323 C C    . LEU   A 1 285 ? 19.489  -67.483 137.685 1   85.503  ? 979  LEU   A C    1 ? 
ATOM   4324 O O    . LEU   A 1 285 ? 18.705  -68.238 138.237 1   105.629 ? 979  LEU   A O    1 ? 
ATOM   4325 C CB   . LEU   A 1 285 ? 18.302  -66.814 135.592 1   104.736 ? 979  LEU   A CB   1 ? 
ATOM   4326 C CG   . LEU   A 1 285 ? 18.246  -66.579 134.082 1   95.284  ? 979  LEU   A CG   1 ? 
ATOM   4327 C CD1  . LEU   A 1 285 ? 16.813  -66.229 133.727 1   101.375 ? 979  LEU   A CD1  1 ? 
ATOM   4328 C CD2  . LEU   A 1 285 ? 19.184  -65.467 133.658 1   94.078  ? 979  LEU   A CD2  1 ? 
ATOM   4329 H H    . LEU   A 1 285 ? 19.134  -69.453 135.948 1   91.878  ? 979  LEU   A H    1 c 
ATOM   4330 H HA   . LEU   A 1 285 ? 20.353  -66.919 135.893 1   93.969  ? 979  LEU   A HA   1 c 
ATOM   4331 H HB2  . LEU   A 1 285 ? 17.54   -67.384 135.842 1   100.29  ? 979  LEU   A HB2  1 c 
ATOM   4332 H HB3  . LEU   A 1 285 ? 18.168  -65.948 136.041 1   100.166 ? 979  LEU   A HB3  1 c 
ATOM   4333 H HG   . LEU   A 1 285 ? 18.501  -67.416 133.616 1   97.811  ? 979  LEU   A HG   1 c 
ATOM   4334 H HD11 . LEU   A 1 285 ? 16.227  -66.962 133.979 1   99.54   ? 979  LEU   A HD11 1 c 
ATOM   4335 H HD12 . LEU   A 1 285 ? 16.743  -66.075 132.77  1   99.534  ? 979  LEU   A HD12 1 c 
ATOM   4336 H HD13 . LEU   A 1 285 ? 16.547  -65.425 134.204 1   99.534  ? 979  LEU   A HD13 1 c 
ATOM   4337 H HD21 . LEU   A 1 285 ? 20.099  -65.715 133.871 1   94.441  ? 979  LEU   A HD21 1 c 
ATOM   4338 H HD22 . LEU   A 1 285 ? 18.952  -64.649 134.128 1   94.478  ? 979  LEU   A HD22 1 c 
ATOM   4339 H HD23 . LEU   A 1 285 ? 19.104  -65.322 132.7   1   94.443  ? 979  LEU   A HD23 1 c 
ATOM   4340 N N    . VAL   A 1 286 ? 20.261  -66.629 138.353 1   85.999  ? 980  VAL   A N    1 ? 
ATOM   4341 C CA   . VAL   A 1 286 ? 20.323  -66.642 139.805 1   89.919  ? 980  VAL   A CA   1 ? 
ATOM   4342 C C    . VAL   A 1 286 ? 19.749  -65.319 140.273 1   82.279  ? 980  VAL   A C    1 ? 
ATOM   4343 O O    . VAL   A 1 286 ? 20.325  -64.279 140.007 1   82.394  ? 980  VAL   A O    1 ? 
ATOM   4344 C CB   . VAL   A 1 286 ? 21.73   -66.864 140.403 1   90.183  ? 980  VAL   A CB   1 ? 
ATOM   4345 C CG1  . VAL   A 1 286 ? 22.632  -67.67  139.477 1   85.456  ? 980  VAL   A CG1  1 ? 
ATOM   4346 C CG2  . VAL   A 1 286 ? 22.424  -65.564 140.792 1   93.035  ? 980  VAL   A CG2  1 ? 
ATOM   4347 H H    . VAL   A 1 286 ? 20.766  -66.02  137.895 1   86.859  ? 980  VAL   A H    1 c 
ATOM   4348 H HA   . VAL   A 1 286 ? 19.744  -67.359 140.129 1   87.884  ? 980  VAL   A HA   1 c 
ATOM   4349 H HB   . VAL   A 1 286 ? 21.611  -67.391 141.228 1   89.75   ? 980  VAL   A HB   1 c 
ATOM   4350 H HG11 . VAL   A 1 286 ? 22.873  -67.129 138.706 1   86.817  ? 980  VAL   A HG11 1 c 
ATOM   4351 H HG12 . VAL   A 1 286 ? 22.162  -68.467 139.178 1   86.821  ? 980  VAL   A HG12 1 c 
ATOM   4352 H HG13 . VAL   A 1 286 ? 23.438  -67.929 139.954 1   86.821  ? 980  VAL   A HG13 1 c 
ATOM   4353 H HG21 . VAL   A 1 286 ? 23.33   -65.759 141.083 1   92.081  ? 980  VAL   A HG21 1 c 
ATOM   4354 H HG22 . VAL   A 1 286 ? 21.941  -65.137 141.52  1   92.011  ? 980  VAL   A HG22 1 c 
ATOM   4355 H HG23 . VAL   A 1 286 ? 22.457  -64.967 140.025 1   92.012  ? 980  VAL   A HG23 1 c 
ATOM   4356 N N    . ILE   A 1 287 ? 18.609  -65.384 140.957 1   93.357  ? 981  ILE   A N    1 ? 
ATOM   4357 C CA   . ILE   A 1 287 ? 17.882  -64.203 141.384 1   100.612 ? 981  ILE   A CA   1 ? 
ATOM   4358 C C    . ILE   A 1 287 ? 17.503  -64.41  142.842 1   101.955 ? 981  ILE   A C    1 ? 
ATOM   4359 O O    . ILE   A 1 287 ? 17.02   -65.478 143.197 1   108.315 ? 981  ILE   A O    1 ? 
ATOM   4360 C CB   . ILE   A 1 287 ? 16.636  -63.991 140.5   1   109.624 ? 981  ILE   A CB   1 ? 
ATOM   4361 C CG1  . ILE   A 1 287 ? 17.019  -63.745 139.03  1   107.635 ? 981  ILE   A CG1  1 ? 
ATOM   4362 C CG2  . ILE   A 1 287 ? 15.741  -62.877 141.044 1   119.053 ? 981  ILE   A CG2  1 ? 
ATOM   4363 C CD1  . ILE   A 1 287 ? 15.857  -63.852 138.055 1   108.019 ? 981  ILE   A CD1  1 ? 
ATOM   4364 H H    . ILE   A 1 287 ? 18.266  -66.204 141.168 1   92.137  ? 981  ILE   A H    1 c 
ATOM   4365 H HA   . ILE   A 1 287 ? 18.463  -63.422 141.309 1   100.875 ? 981  ILE   A HA   1 c 
ATOM   4366 H HB   . ILE   A 1 287 ? 16.119  -64.82  140.528 1   109.196 ? 981  ILE   A HB   1 c 
ATOM   4367 H HG12 . ILE   A 1 287 ? 17.411  -62.851 138.954 1   108.122 ? 981  ILE   A HG12 1 c 
ATOM   4368 H HG13 . ILE   A 1 287 ? 17.704  -64.394 138.769 1   107.928 ? 981  ILE   A HG13 1 c 
ATOM   4369 H HG21 . ILE   A 1 287 ? 15.014  -62.709 140.423 1   116.077 ? 981  ILE   A HG21 1 c 
ATOM   4370 H HG22 . ILE   A 1 287 ? 16.264  -62.064 141.154 1   116.157 ? 981  ILE   A HG22 1 c 
ATOM   4371 H HG23 . ILE   A 1 287 ? 15.373  -63.142 141.903 1   116.094 ? 981  ILE   A HG23 1 c 
ATOM   4372 H HD11 . ILE   A 1 287 ? 15.399  -64.705 138.185 1   107.932 ? 981  ILE   A HD11 1 c 
ATOM   4373 H HD12 . ILE   A 1 287 ? 16.195  -63.804 137.14  1   107.932 ? 981  ILE   A HD12 1 c 
ATOM   4374 H HD13 . ILE   A 1 287 ? 15.229  -63.121 138.206 1   108.014 ? 981  ILE   A HD13 1 c 
ATOM   4375 N N    . GLN   A 1 288 ? 17.685  -63.368 143.657 1   116.026 ? 982  GLN   A N    1 ? 
ATOM   4376 C CA   . GLN   A 1 288 ? 17.357  -63.409 145.075 1   120.77  ? 982  GLN   A CA   1 ? 
ATOM   4377 C C    . GLN   A 1 288 ? 15.883  -63.753 145.298 1   115.216 ? 982  GLN   A C    1 ? 
ATOM   4378 O O    . GLN   A 1 288 ? 15.004  -63.079 144.771 1   124.472 ? 982  GLN   A O    1 ? 
ATOM   4379 C CB   . GLN   A 1 288 ? 17.64   -62.04  145.686 1   131.503 ? 982  GLN   A CB   1 ? 
ATOM   4380 C CG   . GLN   A 1 288 ? 19.048  -61.54  145.394 1   141.846 ? 982  GLN   A CG   1 ? 
ATOM   4381 C CD   . GLN   A 1 288 ? 19.758  -61.033 146.63  1   147.882 ? 982  GLN   A CD   1 ? 
ATOM   4382 O OE1  . GLN   A 1 288 ? 19.864  -61.744 147.635 1   128.467 ? 982  GLN   A OE1  1 ? 
ATOM   4383 N NE2  . GLN   A 1 288 ? 20.263  -59.807 146.571 1   157.429 ? 982  GLN   A NE2  1 ? 
ATOM   4384 H H    . GLN   A 1 288 ? 18.014  -62.59  143.307 1   113.776 ? 982  GLN   A H    1 c 
ATOM   4385 H HA   . GLN   A 1 288 ? 17.925  -64.094 145.512 1   120.609 ? 982  GLN   A HA   1 c 
ATOM   4386 H HB2  . GLN   A 1 288 ? 16.993  -61.394 145.331 1   131.105 ? 982  GLN   A HB2  1 c 
ATOM   4387 H HB3  . GLN   A 1 288 ? 17.508  -62.092 146.655 1   131.264 ? 982  GLN   A HB3  1 c 
ATOM   4388 H HG2  . GLN   A 1 288 ? 19.579  -62.269 145.007 1   140.334 ? 982  GLN   A HG2  1 c 
ATOM   4389 H HG3  . GLN   A 1 288 ? 19.004  -60.819 144.73  1   140.866 ? 982  GLN   A HG3  1 c 
ATOM   4390 H HE21 . GLN   A 1 288 ? 20.573  -59.423 147.308 1   154.157 ? 982  GLN   A HE21 1 c 
ATOM   4391 H HE22 . GLN   A 1 288 ? 20.293  -59.371 145.798 1   154.152 ? 982  GLN   A HE22 1 c 
ATOM   4392 N N    . GLY   A 1 289 ? 15.623  -64.783 146.116 1   115.441 ? 983  GLY   A N    1 ? 
ATOM   4393 C CA   . GLY   A 1 289 ? 14.268  -65.174 146.476 1   128.023 ? 983  GLY   A CA   1 ? 
ATOM   4394 C C    . GLY   A 1 289 ? 13.445  -65.585 145.256 1   128.685 ? 983  GLY   A C    1 ? 
ATOM   4395 O O    . GLY   A 1 289 ? 12.253  -65.289 145.174 1   124.468 ? 983  GLY   A O    1 ? 
ATOM   4396 H H    . GLY   A 1 289 ? 16.32   -65.26  146.465 1   118.155 ? 983  GLY   A H    1 c 
ATOM   4397 H HA2  . GLY   A 1 289 ? 14.31   -65.927 147.111 1   125.043 ? 983  GLY   A HA2  1 c 
ATOM   4398 H HA3  . GLY   A 1 289 ? 13.827  -64.419 146.93  1   125.043 ? 983  GLY   A HA3  1 c 
ATOM   4399 N N    . ASP   A 1 290 ? 14.091  -66.312 144.337 1   136.984 ? 984  ASP   A N    1 ? 
ATOM   4400 C CA   . ASP   A 1 290 ? 13.476  -66.765 143.103 1   132.38  ? 984  ASP   A CA   1 ? 
ATOM   4401 C C    . ASP   A 1 290 ? 12.286  -67.668 143.41  1   136.313 ? 984  ASP   A C    1 ? 
ATOM   4402 O O    . ASP   A 1 290 ? 11.264  -67.586 142.738 1   132.699 ? 984  ASP   A O    1 ? 
ATOM   4403 C CB   . ASP   A 1 290 ? 14.482  -67.528 142.268 1   140.315 ? 984  ASP   A CB   1 ? 
ATOM   4404 C CG   . ASP   A 1 290 ? 14.328  -67.401 140.767 1   126.289 ? 984  ASP   A CG   1 ? 
ATOM   4405 O OD1  . ASP   A 1 290 ? 13.23   -67.005 140.326 1   109.525 ? 984  ASP   A OD1  1 ? 
ATOM   4406 O OD2  . ASP   A 1 290 ? 15.323  -67.701 140.077 1   124.818 ? 984  ASP   A OD2  1 ? 
ATOM   4407 H H    . ASP   A 1 290 ? 14.96   -66.544 144.498 1   133.792 ? 984  ASP   A H    1 c 
ATOM   4408 H HA   . ASP   A 1 290 ? 13.163  -65.981 142.602 1   135.199 ? 984  ASP   A HA   1 c 
ATOM   4409 H HB2  . ASP   A 1 290 ? 15.386  -67.229 142.495 1   134.886 ? 984  ASP   A HB2  1 c 
ATOM   4410 H HB3  . ASP   A 1 290 ? 14.421  -68.477 142.499 1   135.082 ? 984  ASP   A HB3  1 c 
ATOM   4411 N N    . GLU   A 1 291 ? 12.438  -68.533 144.425 1   143.11  ? 985  GLU   A N    1 ? 
ATOM   4412 C CA   . GLU   A 1 291 ? 11.424  -69.522 144.756 1   147.404 ? 985  GLU   A CA   1 ? 
ATOM   4413 C C    . GLU   A 1 291 ? 10.113  -68.819 145.143 1   153.23  ? 985  GLU   A C    1 ? 
ATOM   4414 O O    . GLU   A 1 291 ? 9.074   -69.211 144.628 1   145.222 ? 985  GLU   A O    1 ? 
ATOM   4415 C CB   . GLU   A 1 291 ? 11.999  -70.522 145.765 1   125.946 ? 985  GLU   A CB   1 ? 
ATOM   4416 H H    . GLU   A 1 291 ? 13.203  -68.505 144.925 1   142.175 ? 985  GLU   A H    1 c 
ATOM   4417 H HA   . GLU   A 1 291 ? 11.242  -70.04  143.931 1   143.305 ? 985  GLU   A HA   1 c 
ATOM   4418 H HB2  . GLU   A 1 291 ? 12.925  -70.469 145.809 0   135.59  ? 985  GLU   A HB2  1 c 
ATOM   4419 H HB3  . GLU   A 1 291 ? 11.191  -70.901 146.311 0   135.59  ? 985  GLU   A HB3  1 c 
ATOM   4420 N N    . ARG   A 1 292 ? 10.173  -67.742 145.961 1   161.546 ? 986  ARG   A N    1 ? 
ATOM   4421 C CA   . ARG   A 1 292 ? 9.022   -67.08  146.592 1   150.944 ? 986  ARG   A CA   1 ? 
ATOM   4422 C C    . ARG   A 1 292 ? 7.973   -66.56  145.597 1   153.612 ? 986  ARG   A C    1 ? 
ATOM   4423 O O    . ARG   A 1 292 ? 6.781   -66.786 145.8   1   147.431 ? 986  ARG   A O    1 ? 
ATOM   4424 C CB   . ARG   A 1 292 ? 9.449   -65.895 147.479 1   119.462 ? 986  ARG   A CB   1 ? 
ATOM   4425 H H    . ARG   A 1 292 ? 11.001  -67.4   146.137 1   156.645 ? 986  ARG   A H    1 c 
ATOM   4426 H HA   . ARG   A 1 292 ? 8.58    -67.745 147.179 1   146.957 ? 986  ARG   A HA   1 c 
ATOM   4427 H HB2  . ARG   A 1 292 ? 10.439  -65.928 147.524 0   125.71  ? 986  ARG   A HB2  1 c 
ATOM   4428 H HB3  . ARG   A 1 292 ? 8.668   -65.486 147.875 0   125.71  ? 986  ARG   A HB3  1 c 
ATOM   4429 N N    . MET   A 1 293 ? 8.417   -65.907 144.505 1   161.551 ? 987  MET   A N    1 ? 
ATOM   4430 C CA   . MET   A 1 293 ? 7.647   -64.93  143.721 1   149.497 ? 987  MET   A CA   1 ? 
ATOM   4431 C C    . MET   A 1 293 ? 6.482   -65.545 142.927 1   148.459 ? 987  MET   A C    1 ? 
ATOM   4432 O O    . MET   A 1 293 ? 6.624   -66.612 142.334 1   146.868 ? 987  MET   A O    1 ? 
ATOM   4433 C CB   . MET   A 1 293 ? 8.547   -64.232 142.689 1   138.558 ? 987  MET   A CB   1 ? 
ATOM   4434 C CG   . MET   A 1 293 ? 10.025  -64.295 143.007 1   132.819 ? 987  MET   A CG   1 ? 
ATOM   4435 S SD   . MET   A 1 293 ? 10.946  -63.078 142.054 1   138.742 ? 987  MET   A SD   1 ? 
ATOM   4436 C CE   . MET   A 1 293 ? 12.513  -63.046 142.943 1   133.202 ? 987  MET   A CE   1 ? 
ATOM   4437 H H    . MET   A 1 293 ? 9.258   -66.116 144.217 1   156.092 ? 987  MET   A H    1 c 
ATOM   4438 H HA   . MET   A 1 293 ? 7.282   -64.255 144.347 1   149.52  ? 987  MET   A HA   1 c 
ATOM   4439 H HB2  . MET   A 1 293 ? 8.396   -64.642 141.811 1   139.676 ? 987  MET   A HB2  1 c 
ATOM   4440 H HB3  . MET   A 1 293 ? 8.277   -63.291 142.628 1   139.605 ? 987  MET   A HB3  1 c 
ATOM   4441 H HG2  . MET   A 1 293 ? 10.166  -64.125 143.96  1   135.577 ? 987  MET   A HG2  1 c 
ATOM   4442 H HG3  . MET   A 1 293 ? 10.37   -65.184 142.799 1   135.623 ? 987  MET   A HG3  1 c 
ATOM   4443 H HE1  . MET   A 1 293 ? 13.089  -62.36  142.559 1   134.562 ? 987  MET   A HE1  1 c 
ATOM   4444 H HE2  . MET   A 1 293 ? 12.349  -62.846 143.882 1   134.562 ? 987  MET   A HE2  1 c 
ATOM   4445 H HE3  . MET   A 1 293 ? 12.948  -63.915 142.866 1   134.566 ? 987  MET   A HE3  1 c 
ATOM   4446 N N    . HIS   A 1 294 ? 5.347   -64.82  142.855 1   153.284 ? 988  HIS   A N    1 ? 
ATOM   4447 C CA   . HIS   A 1 294 ? 4.18    -65.196 142.06  1   152.076 ? 988  HIS   A CA   1 ? 
ATOM   4448 C C    . HIS   A 1 294 ? 3.715   -63.98  141.257 1   157.247 ? 988  HIS   A C    1 ? 
ATOM   4449 O O    . HIS   A 1 294 ? 3.758   -62.859 141.754 1   171.164 ? 988  HIS   A O    1 ? 
ATOM   4450 C CB   . HIS   A 1 294 ? 3.035   -65.724 142.941 1   139.29  ? 988  HIS   A CB   1 ? 
ATOM   4451 H H    . HIS   A 1 294 ? 5.304   -64.042 143.334 1   151.846 ? 988  HIS   A H    1 c 
ATOM   4452 H HA   . HIS   A 1 294 ? 4.447   -65.904 141.424 1   150.838 ? 988  HIS   A HA   1 c 
ATOM   4453 H HB2  . HIS   A 1 294 ? 3.394   -65.974 143.849 0   144.41  ? 988  HIS   A HB2  1 c 
ATOM   4454 H HB3  . HIS   A 1 294 ? 2.133   -65.37  142.622 0   144.41  ? 988  HIS   A HB3  1 c 
ATOM   4455 N N    . LEU   A 1 295 ? 3.261   -64.2   140.013 1   161.782 ? 989  LEU   A N    1 ? 
ATOM   4456 C CA   . LEU   A 1 295 ? 2.794   -63.128 139.142 1   150.804 ? 989  LEU   A CA   1 ? 
ATOM   4457 C C    . LEU   A 1 295 ? 1.362   -63.379 138.677 1   149.455 ? 989  LEU   A C    1 ? 
ATOM   4458 O O    . LEU   A 1 295 ? 1.046   -64.491 138.26  1   139.735 ? 989  LEU   A O    1 ? 
ATOM   4459 C CB   . LEU   A 1 295 ? 3.711   -63.01  137.927 1   138.371 ? 989  LEU   A CB   1 ? 
ATOM   4460 C CG   . LEU   A 1 295 ? 4.927   -62.095 138.075 1   132.154 ? 989  LEU   A CG   1 ? 
ATOM   4461 C CD1  . LEU   A 1 295 ? 5.731   -62.15  136.791 1   121.45  ? 989  LEU   A CD1  1 ? 
ATOM   4462 C CD2  . LEU   A 1 295 ? 4.52    -60.665 138.411 1   142.982 ? 989  LEU   A CD2  1 ? 
ATOM   4463 H H    . LEU   A 1 295 ? 3.24    -65.057 139.695 1   158.058 ? 989  LEU   A H    1 c 
ATOM   4464 H HA   . LEU   A 1 295 ? 2.816   -62.283 139.652 1   150.298 ? 989  LEU   A HA   1 c 
ATOM   4465 H HB2  . LEU   A 1 295 ? 4.03    -63.912 137.695 1   139.783 ? 989  LEU   A HB2  1 c 
ATOM   4466 H HB3  . LEU   A 1 295 ? 3.174   -62.687 137.166 1   139.726 ? 989  LEU   A HB3  1 c 
ATOM   4467 H HG   . LEU   A 1 295 ? 5.492   -62.441 138.813 1   133.115 ? 989  LEU   A HG   1 c 
ATOM   4468 H HD11 . LEU   A 1 295 ? 6.019   -63.063 136.628 1   124.497 ? 989  LEU   A HD11 1 c 
ATOM   4469 H HD12 . LEU   A 1 295 ? 6.51    -61.574 136.871 1   124.412 ? 989  LEU   A HD12 1 c 
ATOM   4470 H HD13 . LEU   A 1 295 ? 5.18    -61.847 136.05  1   124.497 ? 989  LEU   A HD13 1 c 
ATOM   4471 H HD21 . LEU   A 1 295 ? 4.151   -60.632 139.309 1   139.831 ? 989  LEU   A HD21 1 c 
ATOM   4472 H HD22 . LEU   A 1 295 ? 3.852   -60.359 137.775 1   139.692 ? 989  LEU   A HD22 1 c 
ATOM   4473 H HD23 . LEU   A 1 295 ? 5.299   -60.086 138.362 1   139.723 ? 989  LEU   A HD23 1 c 
ATOM   4474 N N    . PRO   A 1 296 ? 0.494   -62.34  138.6   1   156.026 ? 990  PRO   A N    1 ? 
ATOM   4475 C CA   . PRO   A 1 296 ? -0.89   -62.562 138.208 1   149.701 ? 990  PRO   A CA   1 ? 
ATOM   4476 C C    . PRO   A 1 296 ? -0.963  -63.59  137.083 1   130.91  ? 990  PRO   A C    1 ? 
ATOM   4477 O O    . PRO   A 1 296 ? -1.957  -63.614 136.336 1   118.083 ? 990  PRO   A O    1 ? 
ATOM   4478 C CB   . PRO   A 1 296 ? -1.393  -61.156 137.839 1   145.581 ? 990  PRO   A CB   1 ? 
ATOM   4479 C CG   . PRO   A 1 296 ? -0.129  -60.328 137.686 1   137.993 ? 990  PRO   A CG   1 ? 
ATOM   4480 C CD   . PRO   A 1 296 ? 0.821   -60.908 138.69  1   147.173 ? 990  PRO   A CD   1 ? 
ATOM   4481 H HA   . PRO   A 1 296 ? -1.394  -62.893 138.98  1   146.494 ? 990  PRO   A HA   1 c 
ATOM   4482 H HB2  . PRO   A 1 296 ? -1.901  -61.173 137.005 1   144.467 ? 990  PRO   A HB2  1 c 
ATOM   4483 H HB3  . PRO   A 1 296 ? -1.961  -60.794 138.546 1   144.671 ? 990  PRO   A HB3  1 c 
ATOM   4484 H HG2  . PRO   A 1 296 ? 0.233   -60.407 136.781 1   141.737 ? 990  PRO   A HG2  1 c 
ATOM   4485 H HG3  . PRO   A 1 296 ? -0.303  -59.385 137.878 1   141.737 ? 990  PRO   A HG3  1 c 
ATOM   4486 H HD2  . PRO   A 1 296 ? 1.747   -60.74  138.442 1   146.991 ? 990  PRO   A HD2  1 c 
ATOM   4487 H HD3  . PRO   A 1 296 ? 0.652   -60.564 139.589 1   147.024 ? 990  PRO   A HD3  1 c 
ATOM   4488 N N    . ARG   A 1 305 ? -15.277 -59.613 137.929 1   153.855 ? 999  ARG   A N    1 ? 
ATOM   4489 C CA   . ARG   A 1 305 ? -13.991 -59.446 138.661 1   156.084 ? 999  ARG   A CA   1 ? 
ATOM   4490 C C    . ARG   A 1 305 ? -12.848 -59.581 137.647 1   161.103 ? 999  ARG   A C    1 ? 
ATOM   4491 O O    . ARG   A 1 305 ? -12.931 -60.405 136.74  1   164.012 ? 999  ARG   A O    1 ? 
ATOM   4492 C CB   . ARG   A 1 305 ? -13.945 -60.418 139.853 1   127.927 ? 999  ARG   A CB   1 ? 
ATOM   4493 H H    . ARG   A 1 305 ? -15.977 -59.512 138.489 1   154.353 ? 999  ARG   A H    1 c 
ATOM   4494 H HA   . ARG   A 1 305 ? -13.971 -58.525 139.026 1   151.025 ? 999  ARG   A HA   1 c 
ATOM   4495 H HB2  . ARG   A 1 305 ? -13.096 -60.607 140.012 0   132.37  ? 999  ARG   A HB2  1 c 
ATOM   4496 H HB3  . ARG   A 1 305 ? -14.955 -60.627 140.036 0   132.37  ? 999  ARG   A HB3  1 c 
ATOM   4497 N N    . ALA   A 1 306 ? -11.8   -58.753 137.804 1   170.621 ? 1000 ALA   A N    1 ? 
ATOM   4498 C CA   . ALA   A 1 306 ? -10.689 -58.626 136.863 1   171.561 ? 1000 ALA   A CA   1 ? 
ATOM   4499 C C    . ALA   A 1 306 ? -11.065 -57.682 135.713 1   178.773 ? 1000 ALA   A C    1 ? 
ATOM   4500 O O    . ALA   A 1 306 ? -10.462 -56.614 135.585 1   162.182 ? 1000 ALA   A O    1 ? 
ATOM   4501 C CB   . ALA   A 1 306 ? -10.214 -59.986 136.369 1   155.504 ? 1000 ALA   A CB   1 ? 
ATOM   4502 H H    . ALA   A 1 306 ? -11.779 -58.233 138.556 1   168.27  ? 1000 ALA   A H    1 c 
ATOM   4503 H HA   . ALA   A 1 306 ? -9.934  -58.201 137.357 1   169.537 ? 1000 ALA   A HA   1 c 
ATOM   4504 H HB1  . ALA   A 1 306 ? -10.234 -60.626 137.1   1   160.156 ? 1000 ALA   A HB1  1 c 
ATOM   4505 H HB2  . ALA   A 1 306 ? -10.791 -60.298 135.652 1   160.423 ? 1000 ALA   A HB2  1 c 
ATOM   4506 H HB3  . ALA   A 1 306 ? -9.304  -59.911 136.035 1   160.156 ? 1000 ALA   A HB3  1 c 
ATOM   4507 N N    . LEU   A 1 307 ? -12.072 -58.076 134.904 1   181.674 ? 1001 LEU   A N    1 ? 
ATOM   4508 C CA   . LEU   A 1 307 ? -12.506 -57.363 133.701 1   174.594 ? 1001 LEU   A CA   1 ? 
ATOM   4509 C C    . LEU   A 1 307 ? -12.793 -55.896 134.025 1   179.154 ? 1001 LEU   A C    1 ? 
ATOM   4510 O O    . LEU   A 1 307 ? -13.788 -55.609 134.689 1   189.255 ? 1001 LEU   A O    1 ? 
ATOM   4511 C CB   . LEU   A 1 307 ? -13.737 -58.048 133.095 1   138.759 ? 1001 LEU   A CB   1 ? 
ATOM   4512 H H    . LEU   A 1 307 ? -12.512 -58.846 135.122 1   178.586 ? 1001 LEU   A H    1 c 
ATOM   4513 H HA   . LEU   A 1 307 ? -11.766 -57.398 133.043 1   169.722 ? 1001 LEU   A HA   1 c 
ATOM   4514 H HB2  . LEU   A 1 307 ? -13.601 -58.749 132.624 0   149.21  ? 1001 LEU   A HB2  1 c 
ATOM   4515 H HB3  . LEU   A 1 307 ? -14.607 -57.487 133.573 0   149.21  ? 1001 LEU   A HB3  1 c 
ATOM   4516 N N    . MET   A 1 308 ? -11.919 -54.984 133.553 1   185.681 ? 1002 MET   A N    1 ? 
ATOM   4517 C CA   . MET   A 1 308 ? -12.061 -53.554 133.81  1   200.969 ? 1002 MET   A CA   1 ? 
ATOM   4518 C C    . MET   A 1 308 ? -13.111 -52.998 132.849 1   207.62  ? 1002 MET   A C    1 ? 
ATOM   4519 O O    . MET   A 1 308 ? -13.761 -53.785 132.163 1   209.379 ? 1002 MET   A O    1 ? 
ATOM   4520 C CB   . MET   A 1 308 ? -10.747 -52.777 133.634 1   193.675 ? 1002 MET   A CB   1 ? 
ATOM   4521 C CG   . MET   A 1 308 ? -9.496  -53.605 133.787 1   190.776 ? 1002 MET   A CG   1 ? 
ATOM   4522 S SD   . MET   A 1 308 ? -9.079  -54.376 132.212 1   179.993 ? 1002 MET   A SD   1 ? 
ATOM   4523 C CE   . MET   A 1 308 ? -7.606  -53.469 131.717 1   154.545 ? 1002 MET   A CE   1 ? 
ATOM   4524 H H    . MET   A 1 308 ? -11.22  -55.269 133.037 1   187.191 ? 1002 MET   A H    1 c 
ATOM   4525 H HA   . MET   A 1 308 ? -12.389 -53.435 134.738 1   197.603 ? 1002 MET   A HA   1 c 
ATOM   4526 H HB2  . MET   A 1 308 ? -10.746 -52.368 132.745 1   193.962 ? 1002 MET   A HB2  1 c 
ATOM   4527 H HB3  . MET   A 1 308 ? -10.727 -52.05  134.293 1   194.493 ? 1002 MET   A HB3  1 c 
ATOM   4528 H HG2  . MET   A 1 308 ? -8.754  -53.035 134.074 1   189.332 ? 1002 MET   A HG2  1 c 
ATOM   4529 H HG3  . MET   A 1 308 ? -9.633  -54.298 134.464 1   189.181 ? 1002 MET   A HG3  1 c 
ATOM   4530 H HE1  . MET   A 1 308 ? -7.424  -53.634 130.773 1   160.532 ? 1002 MET   A HE1  1 c 
ATOM   4531 H HE2  . MET   A 1 308 ? -7.745  -52.515 131.863 1   160.541 ? 1002 MET   A HE2  1 c 
ATOM   4532 H HE3  . MET   A 1 308 ? -6.847  -53.769 132.252 1   160.535 ? 1002 MET   A HE3  1 c 
ATOM   4533 N N    . ASP   A 1 309 ? -13.294 -51.664 132.854 1   207.613 ? 1003 ASP   A N    1 ? 
ATOM   4534 C CA   . ASP   A 1 309 ? -14.188 -50.955 131.944 1   202.674 ? 1003 ASP   A CA   1 ? 
ATOM   4535 C C    . ASP   A 1 309 ? -15.637 -51.408 132.15  1   221.827 ? 1003 ASP   A C    1 ? 
ATOM   4536 O O    . ASP   A 1 309 ? -16.397 -50.738 132.845 1   235.199 ? 1003 ASP   A O    1 ? 
ATOM   4537 C CB   . ASP   A 1 309 ? -13.728 -51.073 130.498 1   171.935 ? 1003 ASP   A CB   1 ? 
ATOM   4538 H H    . ASP   A 1 309 ? -12.836 -51.169 133.471 1   206.367 ? 1003 ASP   A H    1 c 
ATOM   4539 H HA   . ASP   A 1 309 ? -14.14  -49.998 132.167 1   200.678 ? 1003 ASP   A HA   1 c 
ATOM   4540 H HB2  . ASP   A 1 309 ? -12.76  -51.01  130.485 0   182.64  ? 1003 ASP   A HB2  1 c 
ATOM   4541 H HB3  . ASP   A 1 309 ? -14.527 -51.066 129.922 0   182.64  ? 1003 ASP   A HB3  1 c 
ATOM   4542 N N    . GLU   A 1 310 ? -16.004 -52.549 131.537 1   232.793 ? 1004 GLU   A N    1 ? 
ATOM   4543 C CA   . GLU   A 1 310 ? -17.371 -53.063 131.496 1   215.3   ? 1004 GLU   A CA   1 ? 
ATOM   4544 C C    . GLU   A 1 310 ? -17.645 -53.894 132.757 1   189.03  ? 1004 GLU   A C    1 ? 
ATOM   4545 O O    . GLU   A 1 310 ? -16.792 -54.664 133.208 1   166.904 ? 1004 GLU   A O    1 ? 
ATOM   4546 C CB   . GLU   A 1 310 ? -17.574 -53.879 130.207 1   212.05  ? 1004 GLU   A CB   1 ? 
ATOM   4547 C CG   . GLU   A 1 310 ? -18.986 -53.842 129.622 1   197.201 ? 1004 GLU   A CG   1 ? 
ATOM   4548 C CD   . GLU   A 1 310 ? -19.336 -52.8   128.571 1   178.82  ? 1004 GLU   A CD   1 ? 
ATOM   4549 O OE1  . GLU   A 1 310 ? -20.162 -53.111 127.687 1   137.733 ? 1004 GLU   A OE1  1 ? 
ATOM   4550 O OE2  . GLU   A 1 310 ? -18.821 -51.667 128.653 1   187.524 ? 1004 GLU   A OE2  1 ? 
ATOM   4551 H H    . GLU   A 1 310 ? -15.354 -53.046 131.13  1   225.219 ? 1004 GLU   A H    1 c 
ATOM   4552 H HA   . GLU   A 1 310 ? -17.992 -52.291 131.48  1   212.424 ? 1004 GLU   A HA   1 c 
ATOM   4553 H HB2  . GLU   A 1 310 ? -16.955 -53.545 129.524 1   209.483 ? 1004 GLU   A HB2  1 c 
ATOM   4554 H HB3  . GLU   A 1 310 ? -17.34  -54.813 130.387 1   209.198 ? 1004 GLU   A HB3  1 c 
ATOM   4555 H HG2  . GLU   A 1 310 ? -19.176 -54.723 129.236 1   195.544 ? 1004 GLU   A HG2  1 c 
ATOM   4556 H HG3  . GLU   A 1 310 ? -19.616 -53.73  130.364 1   195.777 ? 1004 GLU   A HG3  1 c 
ATOM   4557 N N    . GLU   A 1 311 ? -18.842 -53.696 133.332 1   167.781 ? 1005 GLU   A N    1 ? 
ATOM   4558 C CA   . GLU   A 1 311 ? -19.409 -54.587 134.338 1   163.795 ? 1005 GLU   A CA   1 ? 
ATOM   4559 C C    . GLU   A 1 311 ? -20.265 -55.653 133.643 1   166.266 ? 1005 GLU   A C    1 ? 
ATOM   4560 O O    . GLU   A 1 311 ? -20.243 -56.811 134.049 1   144.299 ? 1005 GLU   A O    1 ? 
ATOM   4561 C CB   . GLU   A 1 311 ? -20.213 -53.798 135.377 1   147.228 ? 1005 GLU   A CB   1 ? 
ATOM   4562 H H    . GLU   A 1 311 ? -19.326 -52.96  133.087 1   172.147 ? 1005 GLU   A H    1 c 
ATOM   4563 H HA   . GLU   A 1 311 ? -18.664 -55.042 134.806 1   161.986 ? 1005 GLU   A HA   1 c 
ATOM   4564 H HB2  . GLU   A 1 311 ? -19.674 -53.217 135.875 0   152     ? 1005 GLU   A HB2  1 c 
ATOM   4565 H HB3  . GLU   A 1 311 ? -21.233 -53.866 135.103 0   152     ? 1005 GLU   A HB3  1 c 
ATOM   4566 N N    . ASP   A 1 312 ? -20.944 -55.254 132.548 1   182.175 ? 1006 ASP   A N    1 ? 
ATOM   4567 C CA   . ASP   A 1 312 ? -22.027 -55.98  131.89  1   179.416 ? 1006 ASP   A CA   1 ? 
ATOM   4568 C C    . ASP   A 1 312 ? -21.614 -57.344 131.337 1   175.213 ? 1006 ASP   A C    1 ? 
ATOM   4569 O O    . ASP   A 1 312 ? -22.42  -58.268 131.395 1   158.479 ? 1006 ASP   A O    1 ? 
ATOM   4570 C CB   . ASP   A 1 312 ? -22.653 -55.171 130.757 1   157.301 ? 1006 ASP   A CB   1 ? 
ATOM   4571 H H    . ASP   A 1 312 ? -20.707 -54.449 132.187 1   177.417 ? 1006 ASP   A H    1 c 
ATOM   4572 H HA   . ASP   A 1 312 ? -22.737 -56.126 132.556 1   174.714 ? 1006 ASP   A HA   1 c 
ATOM   4573 H HB2  . ASP   A 1 312 ? -21.907 -54.833 130.143 0   163.55  ? 1006 ASP   A HB2  1 c 
ATOM   4574 H HB3  . ASP   A 1 312 ? -23.632 -55.213 130.712 0   163.55  ? 1006 ASP   A HB3  1 c 
ATOM   4575 N N    . MET   A 1 313 ? -20.392 -57.48  130.798 1   167.085 ? 1007 MET   A N    1 ? 
ATOM   4576 C CA   . MET   A 1 313 ? -20.09  -58.533 129.839 1   156.471 ? 1007 MET   A CA   1 ? 
ATOM   4577 C C    . MET   A 1 313 ? -19.369 -59.724 130.47  1   139.958 ? 1007 MET   A C    1 ? 
ATOM   4578 O O    . MET   A 1 313 ? -18.275 -59.583 131.007 1   128.355 ? 1007 MET   A O    1 ? 
ATOM   4579 C CB   . MET   A 1 313 ? -19.216 -57.988 128.705 1   142.383 ? 1007 MET   A CB   1 ? 
ATOM   4580 H H    . MET   A 1 313 ? -19.728 -56.901 131.04  1   166.443 ? 1007 MET   A H    1 c 
ATOM   4581 H HA   . MET   A 1 313 ? -20.946 -58.853 129.456 1   152.491 ? 1007 MET   A HA   1 c 
ATOM   4582 H HB2  . MET   A 1 313 ? -18.452 -58.148 128.815 0   151.47  ? 1007 MET   A HB2  1 c 
ATOM   4583 H HB3  . MET   A 1 313 ? -20.048 -57.776 127.936 0   151.47  ? 1007 MET   A HB3  1 c 
ATOM   4584 N N    . ASP   A 1 314 ? -19.993 -60.901 130.352 1   128.524 ? 1008 ASP   A N    1 ? 
ATOM   4585 C CA   . ASP   A 1 314 ? -19.34  -62.181 130.547 1   139.324 ? 1008 ASP   A CA   1 ? 
ATOM   4586 C C    . ASP   A 1 314 ? -19.377 -62.931 129.217 1   145.253 ? 1008 ASP   A C    1 ? 
ATOM   4587 O O    . ASP   A 1 314 ? -19.155 -64.138 129.185 1   144.399 ? 1008 ASP   A O    1 ? 
ATOM   4588 C CB   . ASP   A 1 314 ? -19.998 -62.975 131.668 1   146.558 ? 1008 ASP   A CB   1 ? 
ATOM   4589 C CG   . ASP   A 1 314 ? -21.513 -62.864 131.722 1   136.738 ? 1008 ASP   A CG   1 ? 
ATOM   4590 O OD1  . ASP   A 1 314 ? -22.191 -63.554 130.951 1   141.042 ? 1008 ASP   A OD1  1 ? 
ATOM   4591 O OD2  . ASP   A 1 314 ? -22.004 -62.059 132.515 1   140.602 ? 1008 ASP   A OD2  1 ? 
ATOM   4592 H H    . ASP   A 1 314 ? -20.884 -60.9   130.145 1   133.965 ? 1008 ASP   A H    1 c 
ATOM   4593 H HA   . ASP   A 1 314 ? -18.4   -62.022 130.792 1   139.423 ? 1008 ASP   A HA   1 c 
ATOM   4594 H HB2  . ASP   A 1 314 ? -19.762 -63.923 131.583 1   142.618 ? 1008 ASP   A HB2  1 c 
ATOM   4595 H HB3  . ASP   A 1 314 ? -19.641 -62.656 132.523 1   142.577 ? 1008 ASP   A HB3  1 c 
ATOM   4596 N N    . ASP   A 1 315 ? -19.694 -62.209 128.128 1   138.763 ? 1009 ASP   A N    1 ? 
ATOM   4597 C CA   . ASP   A 1 315 ? -19.633 -62.752 126.773 1   128.803 ? 1009 ASP   A CA   1 ? 
ATOM   4598 C C    . ASP   A 1 315 ? -18.257 -62.496 126.141 1   113.076 ? 1009 ASP   A C    1 ? 
ATOM   4599 O O    . ASP   A 1 315 ? -18.049 -62.834 124.975 1   93.475  ? 1009 ASP   A O    1 ? 
ATOM   4600 C CB   . ASP   A 1 315 ? -20.773 -62.228 125.91  1   127.564 ? 1009 ASP   A CB   1 ? 
ATOM   4601 C CG   . ASP   A 1 315 ? -22.079 -62.988 126.075 1   127.985 ? 1009 ASP   A CG   1 ? 
ATOM   4602 O OD1  . ASP   A 1 315 ? -22.383 -63.829 125.235 1   138.908 ? 1009 ASP   A OD1  1 ? 
ATOM   4603 O OD2  . ASP   A 1 315 ? -22.791 -62.745 127.048 1   145.78  ? 1009 ASP   A OD2  1 ? 
ATOM   4604 H H    . ASP   A 1 315 ? -19.953 -61.339 128.229 1   137.754 ? 1009 ASP   A H    1 c 
ATOM   4605 H HA   . ASP   A 1 315 ? -19.759 -63.726 126.831 1   127.549 ? 1009 ASP   A HA   1 c 
ATOM   4606 H HB2  . ASP   A 1 315 ? -20.935 -61.288 126.132 1   127.956 ? 1009 ASP   A HB2  1 c 
ATOM   4607 H HB3  . ASP   A 1 315 ? -20.515 -62.274 124.966 1   127.694 ? 1009 ASP   A HB3  1 c 
ATOM   4608 N N    . VAL   A 1 316 ? -17.324 -61.926 126.924 1   102.763 ? 1010 VAL   A N    1 ? 
ATOM   4609 C CA   . VAL   A 1 316 ? -15.974 -61.624 126.472 1   96.761  ? 1010 VAL   A CA   1 ? 
ATOM   4610 C C    . VAL   A 1 316 ? -15.245 -62.916 126.081 1   107.517 ? 1010 VAL   A C    1 ? 
ATOM   4611 O O    . VAL   A 1 316 ? -15.303 -63.909 126.809 1   104.251 ? 1010 VAL   A O    1 ? 
ATOM   4612 C CB   . VAL   A 1 316 ? -15.166 -60.834 127.523 1   72.124  ? 1010 VAL   A CB   1 ? 
ATOM   4613 H H    . VAL   A 1 316 ? -17.546 -61.71  127.784 1   104.074 ? 1010 VAL   A H    1 c 
ATOM   4614 H HA   . VAL   A 1 316 ? -16.052 -61.069 125.678 1   94.92   ? 1010 VAL   A HA   1 c 
ATOM   4615 H HB   . VAL   A 1 316 ? -15.772 -60.481 128.108 0   72.34   ? 1010 VAL   A HB   1 c 
ATOM   4616 N N    . VAL   A 1 317 ? -14.557 -62.866 124.928 1   115.861 ? 1011 VAL   A N    1 ? 
ATOM   4617 C CA   . VAL   A 1 317 ? -13.673 -63.915 124.436 1   107.685 ? 1011 VAL   A CA   1 ? 
ATOM   4618 C C    . VAL   A 1 317 ? -12.394 -63.239 123.984 1   102.175 ? 1011 VAL   A C    1 ? 
ATOM   4619 O O    . VAL   A 1 317 ? -12.449 -62.109 123.505 1   101.833 ? 1011 VAL   A O    1 ? 
ATOM   4620 C CB   . VAL   A 1 317 ? -14.261 -64.706 123.257 1   109.217 ? 1011 VAL   A CB   1 ? 
ATOM   4621 C CG1  . VAL   A 1 317 ? -15.405 -65.586 123.719 1   115.685 ? 1011 VAL   A CG1  1 ? 
ATOM   4622 C CG2  . VAL   A 1 317 ? -14.694 -63.776 122.128 1   115.654 ? 1011 VAL   A CG2  1 ? 
ATOM   4623 H H    . VAL   A 1 317 ? -14.645 -62.114 124.416 1   111.631 ? 1011 VAL   A H    1 c 
ATOM   4624 H HA   . VAL   A 1 317 ? -13.47  -64.531 125.165 1   108.383 ? 1011 VAL   A HA   1 c 
ATOM   4625 H HB   . VAL   A 1 317 ? -13.546 -65.292 122.912 1   111.235 ? 1011 VAL   A HB   1 c 
ATOM   4626 H HG11 . VAL   A 1 317 ? -16.107 -65.032 124.1   1   113.73  ? 1011 VAL   A HG11 1 c 
ATOM   4627 H HG12 . VAL   A 1 317 ? -15.084 -66.209 124.393 1   113.729 ? 1011 VAL   A HG12 1 c 
ATOM   4628 H HG13 . VAL   A 1 317 ? -15.758 -66.081 122.965 1   113.728 ? 1011 VAL   A HG13 1 c 
ATOM   4629 H HG21 . VAL   A 1 317 ? -15.178 -64.286 121.458 1   113.66  ? 1011 VAL   A HG21 1 c 
ATOM   4630 H HG22 . VAL   A 1 317 ? -13.911 -63.372 121.72  1   113.475 ? 1011 VAL   A HG22 1 c 
ATOM   4631 H HG23 . VAL   A 1 317 ? -15.272 -63.079 122.481 1   113.66  ? 1011 VAL   A HG23 1 c 
ATOM   4632 N N    . ASP   A 1 318 ? -11.266 -63.941 124.119 1   101.258 ? 1012 ASP   A N    1 ? 
ATOM   4633 C CA   . ASP   A 1 318 ? -10.021 -63.404 123.62  1   104.745 ? 1012 ASP   A CA   1 ? 
ATOM   4634 C C    . ASP   A 1 318 ? -10.024 -63.501 122.095 1   102.956 ? 1012 ASP   A C    1 ? 
ATOM   4635 O O    . ASP   A 1 318 ? -10.708 -64.349 121.518 1   99.96   ? 1012 ASP   A O    1 ? 
ATOM   4636 C CB   . ASP   A 1 318 ? -8.822  -64.105 124.227 1   115.512 ? 1012 ASP   A CB   1 ? 
ATOM   4637 C CG   . ASP   A 1 318 ? -7.584  -63.227 124.266 1   121.087 ? 1012 ASP   A CG   1 ? 
ATOM   4638 O OD1  . ASP   A 1 318 ? -7.544  -62.361 125.156 1   123.792 ? 1012 ASP   A OD1  1 ? 
ATOM   4639 O OD2  . ASP   A 1 318 ? -6.709  -63.374 123.372 1   118.418 ? 1012 ASP   A OD2  1 ? 
ATOM   4640 H H    . ASP   A 1 318 ? -11.275 -64.762 124.52  1   102.506 ? 1012 ASP   A H    1 c 
ATOM   4641 H HA   . ASP   A 1 318 ? -9.971  -62.455 123.874 1   105.637 ? 1012 ASP   A HA   1 c 
ATOM   4642 H HB2  . ASP   A 1 318 ? -9.036  -64.386 125.141 1   114.033 ? 1012 ASP   A HB2  1 c 
ATOM   4643 H HB3  . ASP   A 1 318 ? -8.615  -64.903 123.699 1   114.172 ? 1012 ASP   A HB3  1 c 
ATOM   4644 N N    . ALA   A 1 319 ? -9.263  -62.605 121.459 1   100.325 ? 1013 ALA   A N    1 ? 
ATOM   4645 C CA   . ALA   A 1 319 ? -9.146  -62.574 120.018 1   93.469  ? 1013 ALA   A CA   1 ? 
ATOM   4646 C C    . ALA   A 1 319 ? -8.678  -63.942 119.545 1   91.485  ? 1013 ALA   A C    1 ? 
ATOM   4647 O O    . ALA   A 1 319 ? -9.09   -64.423 118.495 1   94.506  ? 1013 ALA   A O    1 ? 
ATOM   4648 C CB   . ALA   A 1 319 ? -8.17   -61.485 119.629 1   107.86  ? 1013 ALA   A CB   1 ? 
ATOM   4649 H H    . ALA   A 1 319 ? -8.799  -61.988 121.949 1   99.576  ? 1013 ALA   A H    1 c 
ATOM   4650 H HA   . ALA   A 1 319 ? -10.043 -62.384 119.624 1   96.883  ? 1013 ALA   A HA   1 c 
ATOM   4651 H HB1  . ALA   A 1 319 ? -8.523  -60.619 119.893 1   103.42  ? 1013 ALA   A HB1  1 c 
ATOM   4652 H HB2  . ALA   A 1 319 ? -7.319  -61.635 120.075 1   103.463 ? 1013 ALA   A HB2  1 c 
ATOM   4653 H HB3  . ALA   A 1 319 ? -8.033  -61.497 118.667 1   103.536 ? 1013 ALA   A HB3  1 c 
ATOM   4654 N N    . ASP   A 1 320 ? -7.806  -64.533 120.365 1   90.13   ? 1014 ASP   A N    1 ? 
ATOM   4655 C CA   . ASP   A 1 320 ? -7.154  -65.8   120.1   1   94.922  ? 1014 ASP   A CA   1 ? 
ATOM   4656 C C    . ASP   A 1 320 ? -8.171  -66.926 119.981 1   96.154  ? 1014 ASP   A C    1 ? 
ATOM   4657 O O    . ASP   A 1 320 ? -8.01   -67.843 119.18  1   109.542 ? 1014 ASP   A O    1 ? 
ATOM   4658 C CB   . ASP   A 1 320 ? -6.147  -66.089 121.196 1   93.008  ? 1014 ASP   A CB   1 ? 
ATOM   4659 C CG   . ASP   A 1 320 ? -4.919  -65.187 121.173 1   93.766  ? 1014 ASP   A CG   1 ? 
ATOM   4660 O OD1  . ASP   A 1 320 ? -4.605  -64.611 120.112 1   108.972 ? 1014 ASP   A OD1  1 ? 
ATOM   4661 O OD2  . ASP   A 1 320 ? -4.28   -65.051 122.211 1   94.435  ? 1014 ASP   A OD2  1 ? 
ATOM   4662 H H    . ASP   A 1 320 ? -7.587  -64.101 121.14  1   91.708  ? 1014 ASP   A H    1 c 
ATOM   4663 H HA   . ASP   A 1 320 ? -6.677  -65.73  119.246 1   94.628  ? 1014 ASP   A HA   1 c 
ATOM   4664 H HB2  . ASP   A 1 320 ? -6.586  -65.992 122.067 1   93.605  ? 1014 ASP   A HB2  1 c 
ATOM   4665 H HB3  . ASP   A 1 320 ? -5.845  -67.017 121.112 1   93.627  ? 1014 ASP   A HB3  1 c 
ATOM   4666 N N    . GLU   A 1 321 ? -9.211  -66.864 120.803 1   103.921 ? 1015 GLU   A N    1 ? 
ATOM   4667 C CA   . GLU   A 1 321 ? -10.253 -67.877 120.765 1   114.874 ? 1015 GLU   A CA   1 ? 
ATOM   4668 C C    . GLU   A 1 321 ? -11.278 -67.518 119.696 1   108.089 ? 1015 GLU   A C    1 ? 
ATOM   4669 O O    . GLU   A 1 321 ? -12.161 -68.316 119.384 1   102.794 ? 1015 GLU   A O    1 ? 
ATOM   4670 C CB   . GLU   A 1 321 ? -10.952 -68.029 122.116 1   132.217 ? 1015 GLU   A CB   1 ? 
ATOM   4671 C CG   . GLU   A 1 321 ? -10.253 -68.988 123.074 1   126.687 ? 1015 GLU   A CG   1 ? 
ATOM   4672 C CD   . GLU   A 1 321 ? -8.892  -68.529 123.552 1   124.537 ? 1015 GLU   A CD   1 ? 
ATOM   4673 O OE1  . GLU   A 1 321 ? -7.931  -69.32  123.485 1   126.283 ? 1015 GLU   A OE1  1 ? 
ATOM   4674 O OE2  . GLU   A 1 321 ? -8.8    -67.364 123.985 1   123.993 ? 1015 GLU   A OE2  1 ? 
ATOM   4675 H H    . GLU   A 1 321 ? -9.274  -66.184 121.41  1   104.483 ? 1015 GLU   A H    1 c 
ATOM   4676 H HA   . GLU   A 1 321 ? -9.839  -68.745 120.528 1   114.301 ? 1015 GLU   A HA   1 c 
ATOM   4677 H HB2  . GLU   A 1 321 ? -11.016 -67.147 122.54  1   126.572 ? 1015 GLU   A HB2  1 c 
ATOM   4678 H HB3  . GLU   A 1 321 ? -11.865 -68.353 121.967 1   126.51  ? 1015 GLU   A HB3  1 c 
ATOM   4679 H HG2  . GLU   A 1 321 ? -10.822 -69.12  123.859 1   127.395 ? 1015 GLU   A HG2  1 c 
ATOM   4680 H HG3  . GLU   A 1 321 ? -10.151 -69.858 122.633 1   127.321 ? 1015 GLU   A HG3  1 c 
ATOM   4681 N N    . TYR   A 1 322 ? -11.163 -66.307 119.147 1   106.412 ? 1016 TYR   A N    1 ? 
ATOM   4682 C CA   . TYR   A 1 322 ? -12.105 -65.875 118.139 1   102.812 ? 1016 TYR   A CA   1 ? 
ATOM   4683 C C    . TYR   A 1 322 ? -11.502 -66.07  116.759 1   100.012 ? 1016 TYR   A C    1 ? 
ATOM   4684 O O    . TYR   A 1 322 ? -10.6   -65.335 116.382 1   104.297 ? 1016 TYR   A O    1 ? 
ATOM   4685 C CB   . TYR   A 1 322 ? -12.499 -64.418 118.328 1   100.935 ? 1016 TYR   A CB   1 ? 
ATOM   4686 C CG   . TYR   A 1 322 ? -13.518 -63.988 117.286 1   108.94  ? 1016 TYR   A CG   1 ? 
ATOM   4687 C CD1  . TYR   A 1 322 ? -14.812 -64.495 117.285 1   110.56  ? 1016 TYR   A CD1  1 ? 
ATOM   4688 C CD2  . TYR   A 1 322 ? -13.185 -63.075 116.305 1   118.354 ? 1016 TYR   A CD2  1 ? 
ATOM   4689 C CE1  . TYR   A 1 322 ? -15.749 -64.09  116.349 1   115.694 ? 1016 TYR   A CE1  1 ? 
ATOM   4690 C CE2  . TYR   A 1 322 ? -14.113 -62.658 115.367 1   121.145 ? 1016 TYR   A CE2  1 ? 
ATOM   4691 C CZ   . TYR   A 1 322 ? -15.397 -63.163 115.385 1   120.631 ? 1016 TYR   A CZ   1 ? 
ATOM   4692 O OH   . TYR   A 1 322 ? -16.303 -62.739 114.459 1   138.287 ? 1016 TYR   A OH   1 ? 
ATOM   4693 H H    . TYR   A 1 322 ? -10.505 -65.735 119.414 1   105.845 ? 1016 TYR   A H    1 c 
ATOM   4694 H HA   . TYR   A 1 322 ? -12.926 -66.43  118.211 1   102.815 ? 1016 TYR   A HA   1 c 
ATOM   4695 H HB2  . TYR   A 1 322 ? -12.882 -64.304 119.226 1   103.155 ? 1016 TYR   A HB2  1 c 
ATOM   4696 H HB3  . TYR   A 1 322 ? -11.696 -63.855 118.252 1   103.252 ? 1016 TYR   A HB3  1 c 
ATOM   4697 H HD1  . TYR   A 1 322 ? -15.064 -65.116 117.948 1   111.499 ? 1016 TYR   A HD1  1 c 
ATOM   4698 H HD2  . TYR   A 1 322 ? -12.315 -62.711 116.287 1   116.552 ? 1016 TYR   A HD2  1 c 
ATOM   4699 H HE1  . TYR   A 1 322 ? -16.624 -64.438 116.373 1   115.683 ? 1016 TYR   A HE1  1 c 
ATOM   4700 H HE2  . TYR   A 1 322 ? -13.867 -62.027 114.712 1   120.277 ? 1016 TYR   A HE2  1 c 
ATOM   4701 H HH   . TYR   A 1 322 ? -17.02  -63.122 114.604 0   137.93  ? 1016 TYR   A HH   1 c 
ATOM   4702 N N    . LEU   A 1 323 ? -12.02  -67.074 116.04  1   112.117 ? 1017 LEU   A N    1 ? 
ATOM   4703 C CA   . LEU   A 1 323 ? -11.523 -67.468 114.729 1   123.61  ? 1017 LEU   A CA   1 ? 
ATOM   4704 C C    . LEU   A 1 323 ? -12.596 -67.236 113.665 1   139.003 ? 1017 LEU   A C    1 ? 
ATOM   4705 O O    . LEU   A 1 323 ? -13.772 -67.055 113.982 1   126.49  ? 1017 LEU   A O    1 ? 
ATOM   4706 C CB   . LEU   A 1 323 ? -11.072 -68.929 114.799 1   116.224 ? 1017 LEU   A CB   1 ? 
ATOM   4707 C CG   . LEU   A 1 323 ? -9.857  -69.159 115.706 1   109.227 ? 1017 LEU   A CG   1 ? 
ATOM   4708 C CD1  . LEU   A 1 323 ? -10.121 -70.295 116.647 1   108.825 ? 1017 LEU   A CD1  1 ? 
ATOM   4709 C CD2  . LEU   A 1 323 ? -8.571  -69.385 114.955 1   114.95  ? 1017 LEU   A CD2  1 ? 
ATOM   4710 H H    . LEU   A 1 323 ? -12.724 -67.54  116.388 1   111.389 ? 1017 LEU   A H    1 c 
ATOM   4711 H HA   . LEU   A 1 323 ? -10.74  -66.902 114.508 1   122.279 ? 1017 LEU   A HA   1 c 
ATOM   4712 H HB2  . LEU   A 1 323 ? -11.824 -69.471 115.132 1   116.122 ? 1017 LEU   A HB2  1 c 
ATOM   4713 H HB3  . LEU   A 1 323 ? -10.848 -69.23  113.888 1   116.192 ? 1017 LEU   A HB3  1 c 
ATOM   4714 H HG   . LEU   A 1 323 ? -9.733  -68.344 116.258 1   111.484 ? 1017 LEU   A HG   1 c 
ATOM   4715 H HD11 . LEU   A 1 323 ? -10.878 -70.076 117.217 1   108.993 ? 1017 LEU   A HD11 1 c 
ATOM   4716 H HD12 . LEU   A 1 323 ? -9.336  -70.45  117.199 1   108.956 ? 1017 LEU   A HD12 1 c 
ATOM   4717 H HD13 . LEU   A 1 323 ? -10.322 -71.099 116.139 1   108.956 ? 1017 LEU   A HD13 1 c 
ATOM   4718 H HD21 . LEU   A 1 323 ? -8.395  -68.625 114.375 1   113.214 ? 1017 LEU   A HD21 1 c 
ATOM   4719 H HD22 . LEU   A 1 323 ? -8.647  -70.191 114.417 1   113.214 ? 1017 LEU   A HD22 1 c 
ATOM   4720 H HD23 . LEU   A 1 323 ? -7.839  -69.487 115.586 1   113.214 ? 1017 LEU   A HD23 1 c 
ATOM   4721 N N    . ILE   A 1 324 ? -12.163 -67.245 112.394 1   157.267 ? 1018 ILE   A N    1 ? 
ATOM   4722 C CA   . ILE   A 1 324 ? -12.965 -66.792 111.268 1   156.149 ? 1018 ILE   A CA   1 ? 
ATOM   4723 C C    . ILE   A 1 324 ? -13.086 -67.894 110.216 1   168.7   ? 1018 ILE   A C    1 ? 
ATOM   4724 O O    . ILE   A 1 324 ? -12.109 -68.565 109.887 1   138.163 ? 1018 ILE   A O    1 ? 
ATOM   4725 C CB   . ILE   A 1 324 ? -12.41  -65.464 110.7   1   144.87  ? 1018 ILE   A CB   1 ? 
ATOM   4726 C CG1  . ILE   A 1 324 ? -13.168 -64.273 111.287 1   140.054 ? 1018 ILE   A CG1  1 ? 
ATOM   4727 C CG2  . ILE   A 1 324 ? -12.404 -65.424 109.17  1   148.354 ? 1018 ILE   A CG2  1 ? 
ATOM   4728 C CD1  . ILE   A 1 324 ? -14.508 -64.651 111.895 1   135.158 ? 1018 ILE   A CD1  1 ? 
ATOM   4729 H H    . ILE   A 1 324 ? -11.318 -67.551 112.225 1   152.236 ? 1018 ILE   A H    1 c 
ATOM   4730 H HA   . ILE   A 1 324 ? -13.853 -66.624 111.603 1   155.881 ? 1018 ILE   A HA   1 c 
ATOM   4731 H HB   . ILE   A 1 324 ? -11.482 -65.387 110.997 1   146.58  ? 1018 ILE   A HB   1 c 
ATOM   4732 H HG12 . ILE   A 1 324 ? -12.614 -63.855 111.978 1   140     ? 1018 ILE   A HG12 1 c 
ATOM   4733 H HG13 . ILE   A 1 324 ? -13.316 -63.612 110.581 1   140.053 ? 1018 ILE   A HG13 1 c 
ATOM   4734 H HG21 . ILE   A 1 324 ? -12.103 -64.55  108.87  1   147.336 ? 1018 ILE   A HG21 1 c 
ATOM   4735 H HG22 . ILE   A 1 324 ? -13.301 -65.585 108.834 1   147.547 ? 1018 ILE   A HG22 1 c 
ATOM   4736 H HG23 . ILE   A 1 324 ? -11.801 -66.104 108.826 1   147.427 ? 1018 ILE   A HG23 1 c 
ATOM   4737 H HD11 . ILE   A 1 324 ? -15.071 -65.024 111.198 1   137.204 ? 1018 ILE   A HD11 1 c 
ATOM   4738 H HD12 . ILE   A 1 324 ? -14.93  -63.846 112.247 1   136.745 ? 1018 ILE   A HD12 1 c 
ATOM   4739 H HD13 . ILE   A 1 324 ? -14.404 -65.293 112.619 1   136.891 ? 1018 ILE   A HD13 1 c 
ATOM   4740 N N    . PRO   A 1 325 ? -14.299 -68.077 109.633 1   185.652 ? 1019 PRO   A N    1 ? 
ATOM   4741 C CA   . PRO   A 1 325 ? -14.537 -69.095 108.611 1   176.147 ? 1019 PRO   A CA   1 ? 
ATOM   4742 C C    . PRO   A 1 325 ? -13.923 -68.736 107.262 1   161.345 ? 1019 PRO   A C    1 ? 
ATOM   4743 O O    . PRO   A 1 325 ? -12.699 -68.914 107.103 1   137.153 ? 1019 PRO   A O    1 ? 
ATOM   4744 C CB   . PRO   A 1 325 ? -16.064 -69.184 108.524 1   157.959 ? 1019 PRO   A CB   1 ? 
ATOM   4745 C CG   . PRO   A 1 325 ? -16.533 -67.807 108.962 1   152.539 ? 1019 PRO   A CG   1 ? 
ATOM   4746 C CD   . PRO   A 1 325 ? -15.499 -67.277 109.926 1   163.466 ? 1019 PRO   A CD   1 ? 
ATOM   4747 H HA   . PRO   A 1 325 ? -14.175 -69.953 108.917 1   171.482 ? 1019 PRO   A HA   1 c 
ATOM   4748 H HB2  . PRO   A 1 325 ? -16.352 -69.378 107.611 1   160.586 ? 1019 PRO   A HB2  1 c 
ATOM   4749 H HB3  . PRO   A 1 325 ? -16.408 -69.877 109.121 1   160.585 ? 1019 PRO   A HB3  1 c 
ATOM   4750 H HG2  . PRO   A 1 325 ? -16.614 -67.211 108.191 1   156.19  ? 1019 PRO   A HG2  1 c 
ATOM   4751 H HG3  . PRO   A 1 325 ? -17.406 -67.866 109.401 1   156.189 ? 1019 PRO   A HG3  1 c 
ATOM   4752 H HD2  . PRO   A 1 325 ? -15.325 -66.332 109.765 1   164.771 ? 1019 PRO   A HD2  1 c 
ATOM   4753 H HD3  . PRO   A 1 325 ? -15.777 -67.408 110.851 1   165.199 ? 1019 PRO   A HD3  1 c 
HETATM 4754 C C4   . A1ISA B 2 .   ? -0.406  -52.757 119.111 1   127.161 ? 1101 A1ISA A C4   1 ? 
HETATM 4755 C C14  . A1ISA B 2 .   ? -1.486  -51.345 125.981 1   162.677 ? 1101 A1ISA A C14  1 ? 
HETATM 4756 C C5   . A1ISA B 2 .   ? 0.14    -51.62  119.684 1   135.816 ? 1101 A1ISA A C5   1 ? 
HETATM 4757 C C6   . A1ISA B 2 .   ? 0.499   -50.167 121.624 1   170.463 ? 1101 A1ISA A C6   1 ? 
HETATM 4758 C C11  . A1ISA B 2 .   ? 1.826   -50.271 121.978 1   169.523 ? 1101 A1ISA A C11  1 ? 
HETATM 4759 C C7   . A1ISA B 2 .   ? -0.241  -49.069 121.982 1   182.746 ? 1101 A1ISA A C7   1 ? 
HETATM 4760 C C8   . A1ISA B 2 .   ? 0.385   -48.012 122.625 1   183.994 ? 1101 A1ISA A C8   1 ? 
HETATM 4761 C C9   . A1ISA B 2 .   ? 1.721   -48.091 122.953 1   177.105 ? 1101 A1ISA A C9   1 ? 
HETATM 4762 C C10  . A1ISA B 2 .   ? 2.445   -49.214 122.623 1   167.549 ? 1101 A1ISA A C10  1 ? 
HETATM 4763 C C12  . A1ISA B 2 .   ? -0.907  -52.16  121.793 1   141.178 ? 1101 A1ISA A C12  1 ? 
HETATM 4764 C C13  . A1ISA B 2 .   ? -1.857  -52.656 123.825 1   137.746 ? 1101 A1ISA A C13  1 ? 
HETATM 4765 N N1   . A1ISA B 2 .   ? -0.143  -51.306 121.006 1   146.348 ? 1101 A1ISA A N1   1 ? 
HETATM 4766 N N2   . A1ISA B 2 .   ? -1.093  -51.839 123.076 1   139.326 ? 1101 A1ISA A N2   1 ? 
HETATM 4767 C C3   . A1ISA B 2 .   ? -1.217  -53.591 119.849 1   132.547 ? 1101 A1ISA A C3   1 ? 
HETATM 4768 N N3   . A1ISA B 2 .   ? -2.045  -52.349 125.145 1   149.46  ? 1101 A1ISA A N3   1 ? 
HETATM 4769 C C1   . A1ISA B 2 .   ? -1.101  -55.714 118.613 1   142.894 ? 1101 A1ISA A C1   1 ? 
HETATM 4770 C C2   . A1ISA B 2 .   ? -1.765  -54.822 119.271 1   137.296 ? 1101 A1ISA A C2   1 ? 
HETATM 4771 O O1   . A1ISA B 2 .   ? 0.829   -50.833 119.043 1   143.454 ? 1101 A1ISA A O1   1 ? 
HETATM 4772 C C15  . A1ISA B 2 .   ? -0.755  -50.269 125.461 1   155.009 ? 1101 A1ISA A C15  1 ? 
HETATM 4773 C C16  . A1ISA B 2 .   ? -0.24   -49.302 126.311 1   154.579 ? 1101 A1ISA A C16  1 ? 
HETATM 4774 C C17  . A1ISA B 2 .   ? -0.44   -49.4   127.671 1   159.574 ? 1101 A1ISA A C17  1 ? 
HETATM 4775 C C18  . A1ISA B 2 .   ? -1.164  -50.452 128.207 1   156.266 ? 1101 A1ISA A C18  1 ? 
HETATM 4776 C C19  . A1ISA B 2 .   ? -1.67   -51.447 127.372 1   163.285 ? 1101 A1ISA A C19  1 ? 
HETATM 4777 O O2   . A1ISA B 2 .   ? -2.405  -52.515 127.799 1   163.688 ? 1101 A1ISA A O2   1 ? 
HETATM 4778 C C20  . A1ISA B 2 .   ? -3.473  -52.262 128.7   1   166.722 ? 1101 A1ISA A C20  1 ? 
HETATM 4779 N N4   . A1ISA B 2 .   ? -2.439  -53.786 123.356 1   125.444 ? 1101 A1ISA A N4   1 ? 
HETATM 4780 C C21  . A1ISA B 2 .   ? -2.242  -54.111 122.079 1   118.191 ? 1101 A1ISA A C21  1 ? 
HETATM 4781 C C22  . A1ISA B 2 .   ? -1.457  -53.308 121.229 1   130.873 ? 1101 A1ISA A C22  1 ? 
HETATM 4782 H H4   . A1ISA B 2 .   ? -0.252  -52.935 118.208 1   130.724 ? 1101 A1ISA A H4   1 c 
HETATM 4783 H H9   . A1ISA B 2 .   ? 2.313   -51.041 121.751 1   169.323 ? 1101 A1ISA A H9   1 c 
HETATM 4784 H H5   . A1ISA B 2 .   ? -1.148  -49.025 121.762 1   177.927 ? 1101 A1ISA A H5   1 c 
HETATM 4785 H H6   . A1ISA B 2 .   ? -0.107  -47.24  122.851 1   180.885 ? 1101 A1ISA A H6   1 c 
HETATM 4786 H H7   . A1ISA B 2 .   ? 2.144   -47.367 123.387 1   176.287 ? 1101 A1ISA A H7   1 c 
HETATM 4787 H H8   . A1ISA B 2 .   ? 3.361   -49.263 122.841 1   170.311 ? 1101 A1ISA A H8   1 c 
HETATM 4788 H H10  . A1ISA B 2 .   ? -2.62   -52.87  125.55  1   149.456 ? 1101 A1ISA A H10  1 c 
HETATM 4789 H H3   . A1ISA B 2 .   ? -2.683  -54.989 119.412 1   136.856 ? 1101 A1ISA A H3   1 c 
HETATM 4790 H H11  . A1ISA B 2 .   ? -0.626  -50.198 124.533 1   156.518 ? 1101 A1ISA A H11  1 c 
HETATM 4791 H H12  . A1ISA B 2 .   ? 0.249   -48.578 125.957 1   155.904 ? 1101 A1ISA A H12  1 c 
HETATM 4792 H H13  . A1ISA B 2 .   ? -0.083  -48.743 128.246 1   157.644 ? 1101 A1ISA A H13  1 c 
HETATM 4793 H H14  . A1ISA B 2 .   ? -1.283  -50.515 129.139 1   158.647 ? 1101 A1ISA A H14  1 c 
HETATM 4794 H H16  . A1ISA B 2 .   ? -4.035  -53.05  128.764 1   164.441 ? 1101 A1ISA A H16  1 c 
HETATM 4795 H H17  . A1ISA B 2 .   ? -4.001  -51.515 128.374 1   165.369 ? 1101 A1ISA A H17  1 c 
HETATM 4796 H H15  . A1ISA B 2 .   ? -3.114  -52.047 129.576 1   165.017 ? 1101 A1ISA A H15  1 c 
HETATM 4797 H H18  . A1ISA B 2 .   ? -2.632  -54.895 121.74  1   122.894 ? 1101 A1ISA A H18  1 c 
HETATM 4798 O O    . HOH   C 3 .   ? 7.82    -62.831 104.846 1   141.569 ? 1201 HOH   A O    1 ? 
HETATM 4799 O O    . HOH   C 3 .   ? 12.478  -60.391 139.878 1   121.367 ? 1202 HOH   A O    1 ? 
HETATM 4800 O O    . HOH   C 3 .   ? -1.588  -64.643 116.549 1   120.366 ? 1203 HOH   A O    1 ? 
HETATM 4801 O O    . HOH   C 3 .   ? 8.523   -69.612 114.6   1   135.97  ? 1204 HOH   A O    1 ? 
HETATM 4802 O O    . HOH   C 3 .   ? -6.733  -37.253 112.435 1   121.22  ? 1205 HOH   A O    1 ? 
HETATM 4803 O O    . HOH   C 3 .   ? 26.713  -59.809 111.357 1   191.203 ? 1206 HOH   A O    1 ? 
HETATM 4804 O O    . HOH   C 3 .   ? 0.055   -48.425 102.781 1   168.445 ? 1207 HOH   A O    1 ? 
HETATM 4805 O O    . HOH   C 3 .   ? -9.886  -67.346 111.408 1   131.355 ? 1208 HOH   A O    1 ? 
HETATM 4806 O O    . HOH   C 3 .   ? 0.205   -51.280 102.105 1   122.465 ? 1209 HOH   A O    1 ? 
HETATM 4807 O O    . HOH   C 3 .   ? -19.489 -50.046 119.52  1   160.733 ? 1210 HOH   A O    1 ? 
HETATM 4808 O O    . HOH   C 3 .   ? 25.284  -70.978 126.244 1   119.856 ? 1211 HOH   A O    1 ? 
HETATM 4809 O O    . HOH   C 3 .   ? 6.565   -70.384 111.957 1   137.478 ? 1212 HOH   A O    1 ? 
HETATM 4810 O O    . HOH   C 3 .   ? -8.875  -60.233 122.681 1   116.299 ? 1213 HOH   A O    1 ? 
HETATM 4811 O O    . HOH   C 3 .   ? -7.995  -56.961 110.105 1   178.774 ? 1214 HOH   A O    1 ? 
HETATM 4812 O O    . HOH   C 3 .   ? 24.672  -73.149 134.896 1   107.604 ? 1215 HOH   A O    1 ? 
HETATM 4813 O O    . HOH   C 3 .   ? -7.218  -66.226 97.518  1   113.778 ? 1216 HOH   A O    1 ? 
HETATM 4814 O O    . HOH   C 3 .   ? -14.289 -43.116 124.945 1   130.786 ? 1217 HOH   A O    1 ? 
HETATM 4815 O O    . HOH   C 3 .   ? -7.597  -64.144 115.953 1   126.923 ? 1218 HOH   A O    1 ? 
HETATM 4816 O O    . HOH   C 3 .   ? 21.109  -58.755 136.12  1   125.348 ? 1219 HOH   A O    1 ? 
HETATM 4817 O O    . HOH   C 3 .   ? 5.039   -70.059 117.784 1   125.728 ? 1220 HOH   A O    1 ? 
HETATM 4818 O O    . HOH   C 3 .   ? -6.529  -40.302 117.01  1   170.99  ? 1221 HOH   A O    1 ? 
HETATM 4819 O O    . HOH   C 3 .   ? 27.426  -61.54  136.11  1   115.913 ? 1222 HOH   A O    1 ? 
HETATM 4820 O O    . HOH   C 3 .   ? 7.462   -70.095 127.27  1   165.689 ? 1223 HOH   A O    1 ? 
HETATM 4821 O O    . HOH   C 3 .   ? 16.672  -78.874 111.434 1   131.214 ? 1224 HOH   A O    1 ? 
HETATM 4822 O O    . HOH   C 3 .   ? 7.103   -68.586 135.968 1   164.782 ? 1225 HOH   A O    1 ? 
HETATM 4823 O O    . HOH   C 3 .   ? 9.955   -74.319 126.642 1   121.13  ? 1226 HOH   A O    1 ? 
HETATM 4824 O O    . HOH   C 3 .   ? 9.933   -52.893 103.775 1   116.15  ? 1227 HOH   A O    1 ? 
HETATM 4825 O O    . HOH   C 3 .   ? 8.133   -72.392 106.589 1   117.739 ? 1228 HOH   A O    1 ? 
HETATM 4826 O O    . HOH   C 3 .   ? -2.579  -54.99  134.226 1   141.687 ? 1229 HOH   A O    1 ? 
HETATM 4827 O O    . HOH   C 3 .   ? 14.753  -79.052 139.224 1   112.59  ? 1230 HOH   A O    1 ? 
HETATM 4828 O O    . HOH   C 3 .   ? 23.096  -53.656 133.804 1   112.86  ? 1231 HOH   A O    1 ? 
# 
