data_9GZH
# 
_entry.id   9GZH 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9GZH         pdb_00009gzh 10.2210/pdb9gzh/pdb 
WWPDB D_1292142082 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2025-02-12 
2 'Structure model' 1 1 2025-02-26 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation_author.identifier_ORCID' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9GZH 
_pdbx_database_status.recvd_initial_deposition_date   2024-10-04 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              daniel.rauh@tu-dortmund.de 
_pdbx_contact_author.name_first         Daniel 
_pdbx_contact_author.name_last          Rauh 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1970-7642 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Teuber, A.'    1 0000-0002-5385-8735 
'Rauh, D.'      2 0000-0002-1970-7642 
'Mueller, M.P.' 3 0000-0002-1529-8933 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Med.Chem. 
_citation.journal_id_ASTM           JMCMAR 
_citation.journal_id_CSD            0151 
_citation.journal_id_ISSN           0022-2623 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            68 
_citation.language                  ? 
_citation.page_first                3238 
_citation.page_last                 3259 
_citation.title                     
'Design, Synthesis, and SAR of Covalent KIT and PDGFRA Inhibitors&#9472;Exploring Their Potential in Targeting GIST.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acs.jmedchem.4c02472 
_citation.pdbx_database_id_PubMed   39841084 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Schulz, T.'     1  ? 
primary 'Gontla, R.'     2  ? 
primary 'Teuber, A.'     3  ? 
primary 'Beerbaum, M.'   4  ? 
primary 'Fletcher, B.S.' 5  ? 
primary 'Muhlenberg, T.' 6  ? 
primary 'Kaitsiotou, H.' 7  ? 
primary 'Hardick, J.'    8  ? 
primary 'Jeyakumar, K.'  9  ? 
primary 'Keul, M.'       10 ? 
primary 'Muller, M.P.'   11 ? 
primary 'Sievers, S.'    12 ? 
primary 'Bauer, S.'      13 ? 
primary 'Rauh, D.'       14 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Platelet-derived growth factor receptor alpha' 40437.594 1  2.7.10.1 T674I ? ? 
2 non-polymer syn 
'3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-~{N}-[4-(propanoylamino)-3-(trifluoromethyl)phenyl]benzamide' 491.465   1  ? ? 
? ? 
3 water       nat water 18.015    60 ?        ?     ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;PDGF-R-alpha,PDGFR-alpha,Alpha platelet-derived growth factor receptor,Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A,CD140a antigen,Platelet-derived growth factor alpha receptor,Platelet-derived growth factor receptor 2,PDGFR-2
;
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GPGKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAV
KMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIIIEYCFYGDLVNYLHKNRDSFLSHKKKSMLDSEV
KNLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLP
VKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPE
KRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSD
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GPGKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAV
KMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIIIEYCFYGDLVNYLHKNRDSFLSHKKKSMLDSEV
KNLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLP
VKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPE
KRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSD
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-~{N}-[4-(propanoylamino)-3-(trifluoromethyl)phenyl]benzamide' A1IRC 
3 water                                                                                                             HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   GLY n 
1 4   LYS n 
1 5   GLN n 
1 6   LYS n 
1 7   PRO n 
1 8   ARG n 
1 9   TYR n 
1 10  GLU n 
1 11  ILE n 
1 12  ARG n 
1 13  TRP n 
1 14  ARG n 
1 15  VAL n 
1 16  ILE n 
1 17  GLU n 
1 18  SER n 
1 19  ILE n 
1 20  SER n 
1 21  PRO n 
1 22  ASP n 
1 23  GLY n 
1 24  HIS n 
1 25  GLU n 
1 26  TYR n 
1 27  ILE n 
1 28  TYR n 
1 29  VAL n 
1 30  ASP n 
1 31  PRO n 
1 32  MET n 
1 33  GLN n 
1 34  LEU n 
1 35  PRO n 
1 36  TYR n 
1 37  ASP n 
1 38  SER n 
1 39  ARG n 
1 40  TRP n 
1 41  GLU n 
1 42  PHE n 
1 43  PRO n 
1 44  ARG n 
1 45  ASP n 
1 46  GLY n 
1 47  LEU n 
1 48  VAL n 
1 49  LEU n 
1 50  GLY n 
1 51  ARG n 
1 52  VAL n 
1 53  LEU n 
1 54  GLY n 
1 55  SER n 
1 56  GLY n 
1 57  ALA n 
1 58  PHE n 
1 59  GLY n 
1 60  LYS n 
1 61  VAL n 
1 62  VAL n 
1 63  GLU n 
1 64  GLY n 
1 65  THR n 
1 66  ALA n 
1 67  TYR n 
1 68  GLY n 
1 69  LEU n 
1 70  SER n 
1 71  ARG n 
1 72  SER n 
1 73  GLN n 
1 74  PRO n 
1 75  VAL n 
1 76  MET n 
1 77  LYS n 
1 78  VAL n 
1 79  ALA n 
1 80  VAL n 
1 81  LYS n 
1 82  MET n 
1 83  LEU n 
1 84  LYS n 
1 85  PRO n 
1 86  THR n 
1 87  ALA n 
1 88  ARG n 
1 89  SER n 
1 90  SER n 
1 91  GLU n 
1 92  LYS n 
1 93  GLN n 
1 94  ALA n 
1 95  LEU n 
1 96  MET n 
1 97  SER n 
1 98  GLU n 
1 99  LEU n 
1 100 LYS n 
1 101 ILE n 
1 102 MET n 
1 103 THR n 
1 104 HIS n 
1 105 LEU n 
1 106 GLY n 
1 107 PRO n 
1 108 HIS n 
1 109 LEU n 
1 110 ASN n 
1 111 ILE n 
1 112 VAL n 
1 113 ASN n 
1 114 LEU n 
1 115 LEU n 
1 116 GLY n 
1 117 ALA n 
1 118 CYS n 
1 119 THR n 
1 120 LYS n 
1 121 SER n 
1 122 GLY n 
1 123 PRO n 
1 124 ILE n 
1 125 TYR n 
1 126 ILE n 
1 127 ILE n 
1 128 ILE n 
1 129 GLU n 
1 130 TYR n 
1 131 CYS n 
1 132 PHE n 
1 133 TYR n 
1 134 GLY n 
1 135 ASP n 
1 136 LEU n 
1 137 VAL n 
1 138 ASN n 
1 139 TYR n 
1 140 LEU n 
1 141 HIS n 
1 142 LYS n 
1 143 ASN n 
1 144 ARG n 
1 145 ASP n 
1 146 SER n 
1 147 PHE n 
1 148 LEU n 
1 149 SER n 
1 150 HIS n 
1 151 LYS n 
1 152 LYS n 
1 153 LYS n 
1 154 SER n 
1 155 MET n 
1 156 LEU n 
1 157 ASP n 
1 158 SER n 
1 159 GLU n 
1 160 VAL n 
1 161 LYS n 
1 162 ASN n 
1 163 LEU n 
1 164 LEU n 
1 165 SER n 
1 166 ASP n 
1 167 ASP n 
1 168 ASN n 
1 169 SER n 
1 170 GLU n 
1 171 GLY n 
1 172 LEU n 
1 173 THR n 
1 174 LEU n 
1 175 LEU n 
1 176 ASP n 
1 177 LEU n 
1 178 LEU n 
1 179 SER n 
1 180 PHE n 
1 181 THR n 
1 182 TYR n 
1 183 GLN n 
1 184 VAL n 
1 185 ALA n 
1 186 ARG n 
1 187 GLY n 
1 188 MET n 
1 189 GLU n 
1 190 PHE n 
1 191 LEU n 
1 192 ALA n 
1 193 SER n 
1 194 LYS n 
1 195 ASN n 
1 196 CYS n 
1 197 VAL n 
1 198 HIS n 
1 199 ARG n 
1 200 ASP n 
1 201 LEU n 
1 202 ALA n 
1 203 ALA n 
1 204 ARG n 
1 205 ASN n 
1 206 VAL n 
1 207 LEU n 
1 208 LEU n 
1 209 ALA n 
1 210 GLN n 
1 211 GLY n 
1 212 LYS n 
1 213 ILE n 
1 214 VAL n 
1 215 LYS n 
1 216 ILE n 
1 217 CYS n 
1 218 ASP n 
1 219 PHE n 
1 220 GLY n 
1 221 LEU n 
1 222 ALA n 
1 223 ARG n 
1 224 ASP n 
1 225 ILE n 
1 226 MET n 
1 227 HIS n 
1 228 ASP n 
1 229 SER n 
1 230 ASN n 
1 231 TYR n 
1 232 VAL n 
1 233 SER n 
1 234 LYS n 
1 235 GLY n 
1 236 SER n 
1 237 THR n 
1 238 PHE n 
1 239 LEU n 
1 240 PRO n 
1 241 VAL n 
1 242 LYS n 
1 243 TRP n 
1 244 MET n 
1 245 ALA n 
1 246 PRO n 
1 247 GLU n 
1 248 SER n 
1 249 ILE n 
1 250 PHE n 
1 251 ASP n 
1 252 ASN n 
1 253 LEU n 
1 254 TYR n 
1 255 THR n 
1 256 THR n 
1 257 LEU n 
1 258 SER n 
1 259 ASP n 
1 260 VAL n 
1 261 TRP n 
1 262 SER n 
1 263 TYR n 
1 264 GLY n 
1 265 ILE n 
1 266 LEU n 
1 267 LEU n 
1 268 TRP n 
1 269 GLU n 
1 270 ILE n 
1 271 PHE n 
1 272 SER n 
1 273 LEU n 
1 274 GLY n 
1 275 GLY n 
1 276 THR n 
1 277 PRO n 
1 278 TYR n 
1 279 PRO n 
1 280 GLY n 
1 281 MET n 
1 282 MET n 
1 283 VAL n 
1 284 ASP n 
1 285 SER n 
1 286 THR n 
1 287 PHE n 
1 288 TYR n 
1 289 ASN n 
1 290 LYS n 
1 291 ILE n 
1 292 LYS n 
1 293 SER n 
1 294 GLY n 
1 295 TYR n 
1 296 ARG n 
1 297 MET n 
1 298 ALA n 
1 299 LYS n 
1 300 PRO n 
1 301 ASP n 
1 302 HIS n 
1 303 ALA n 
1 304 THR n 
1 305 SER n 
1 306 GLU n 
1 307 VAL n 
1 308 TYR n 
1 309 GLU n 
1 310 ILE n 
1 311 MET n 
1 312 VAL n 
1 313 LYS n 
1 314 CYS n 
1 315 TRP n 
1 316 ASN n 
1 317 SER n 
1 318 GLU n 
1 319 PRO n 
1 320 GLU n 
1 321 LYS n 
1 322 ARG n 
1 323 PRO n 
1 324 SER n 
1 325 PHE n 
1 326 TYR n 
1 327 HIS n 
1 328 LEU n 
1 329 SER n 
1 330 GLU n 
1 331 ILE n 
1 332 VAL n 
1 333 GLU n 
1 334 ASN n 
1 335 LEU n 
1 336 LEU n 
1 337 PRO n 
1 338 GLY n 
1 339 GLN n 
1 340 TYR n 
1 341 LYS n 
1 342 LYS n 
1 343 SER n 
1 344 TYR n 
1 345 GLU n 
1 346 LYS n 
1 347 ILE n 
1 348 HIS n 
1 349 LEU n 
1 350 ASP n 
1 351 PHE n 
1 352 LEU n 
1 353 LYS n 
1 354 SER n 
1 355 ASP n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   355 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'PDGFRA, PDGFR2, RHEPDGFRA' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Spodoptera frugiperda' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     7108 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1IRC non-polymer         . 
'3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-~{N}-[4-(propanoylamino)-3-(trifluoromethyl)phenyl]benzamide' ? 
'C26 H20 F3 N5 O2' 491.465 
ALA   'L-peptide linking' y ALANINE ? 'C3 H7 N O2'       89.093  
ARG   'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1'   175.209 
ASN   'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'      132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'       133.103 
CYS   'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'     121.158 
GLN   'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'     146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'       147.129 
GLY   'peptide linking'   y GLYCINE ? 'C2 H5 N O2'       75.067  
HIS   'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1'   156.162 
HOH   non-polymer         . WATER ? 'H2 O'             18.015  
ILE   'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'      131.173 
LEU   'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'      131.173 
LYS   'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1'   147.195 
MET   'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'    149.211 
PHE   'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'      165.189 
PRO   'L-peptide linking' y PROLINE ? 'C5 H9 N O2'       115.130 
SER   'L-peptide linking' y SERINE ? 'C3 H7 N O3'       105.093 
THR   'L-peptide linking' y THREONINE ? 'C4 H9 N O3'       119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'    204.225 
TYR   'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'      181.189 
VAL   'L-peptide linking' y VALINE ? 'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   547 ?   ?   ?   A . n 
A 1 2   PRO 2   548 ?   ?   ?   A . n 
A 1 3   GLY 3   549 ?   ?   ?   A . n 
A 1 4   LYS 4   550 ?   ?   ?   A . n 
A 1 5   GLN 5   551 ?   ?   ?   A . n 
A 1 6   LYS 6   552 ?   ?   ?   A . n 
A 1 7   PRO 7   553 ?   ?   ?   A . n 
A 1 8   ARG 8   554 ?   ?   ?   A . n 
A 1 9   TYR 9   555 ?   ?   ?   A . n 
A 1 10  GLU 10  556 ?   ?   ?   A . n 
A 1 11  ILE 11  557 ?   ?   ?   A . n 
A 1 12  ARG 12  558 ?   ?   ?   A . n 
A 1 13  TRP 13  559 ?   ?   ?   A . n 
A 1 14  ARG 14  560 ?   ?   ?   A . n 
A 1 15  VAL 15  561 ?   ?   ?   A . n 
A 1 16  ILE 16  562 ?   ?   ?   A . n 
A 1 17  GLU 17  563 ?   ?   ?   A . n 
A 1 18  SER 18  564 ?   ?   ?   A . n 
A 1 19  ILE 19  565 ?   ?   ?   A . n 
A 1 20  SER 20  566 ?   ?   ?   A . n 
A 1 21  PRO 21  567 ?   ?   ?   A . n 
A 1 22  ASP 22  568 ?   ?   ?   A . n 
A 1 23  GLY 23  569 ?   ?   ?   A . n 
A 1 24  HIS 24  570 ?   ?   ?   A . n 
A 1 25  GLU 25  571 ?   ?   ?   A . n 
A 1 26  TYR 26  572 ?   ?   ?   A . n 
A 1 27  ILE 27  573 ?   ?   ?   A . n 
A 1 28  TYR 28  574 ?   ?   ?   A . n 
A 1 29  VAL 29  575 ?   ?   ?   A . n 
A 1 30  ASP 30  576 ?   ?   ?   A . n 
A 1 31  PRO 31  577 ?   ?   ?   A . n 
A 1 32  MET 32  578 ?   ?   ?   A . n 
A 1 33  GLN 33  579 ?   ?   ?   A . n 
A 1 34  LEU 34  580 ?   ?   ?   A . n 
A 1 35  PRO 35  581 ?   ?   ?   A . n 
A 1 36  TYR 36  582 ?   ?   ?   A . n 
A 1 37  ASP 37  583 583 ASP ASP A . n 
A 1 38  SER 38  584 584 SER SER A . n 
A 1 39  ARG 39  585 585 ARG ARG A . n 
A 1 40  TRP 40  586 586 TRP TRP A . n 
A 1 41  GLU 41  587 587 GLU GLU A . n 
A 1 42  PHE 42  588 588 PHE PHE A . n 
A 1 43  PRO 43  589 589 PRO PRO A . n 
A 1 44  ARG 44  590 590 ARG ARG A . n 
A 1 45  ASP 45  591 591 ASP ASP A . n 
A 1 46  GLY 46  592 592 GLY GLY A . n 
A 1 47  LEU 47  593 593 LEU LEU A . n 
A 1 48  VAL 48  594 594 VAL VAL A . n 
A 1 49  LEU 49  595 595 LEU LEU A . n 
A 1 50  GLY 50  596 596 GLY GLY A . n 
A 1 51  ARG 51  597 597 ARG ARG A . n 
A 1 52  VAL 52  598 598 VAL VAL A . n 
A 1 53  LEU 53  599 599 LEU LEU A . n 
A 1 54  GLY 54  600 600 GLY GLY A . n 
A 1 55  SER 55  601 601 SER SER A . n 
A 1 56  GLY 56  602 602 GLY GLY A . n 
A 1 57  ALA 57  603 603 ALA ALA A . n 
A 1 58  PHE 58  604 604 PHE PHE A . n 
A 1 59  GLY 59  605 605 GLY GLY A . n 
A 1 60  LYS 60  606 606 LYS LYS A . n 
A 1 61  VAL 61  607 607 VAL VAL A . n 
A 1 62  VAL 62  608 608 VAL VAL A . n 
A 1 63  GLU 63  609 609 GLU GLU A . n 
A 1 64  GLY 64  610 610 GLY GLY A . n 
A 1 65  THR 65  611 611 THR THR A . n 
A 1 66  ALA 66  612 612 ALA ALA A . n 
A 1 67  TYR 67  613 613 TYR TYR A . n 
A 1 68  GLY 68  614 614 GLY GLY A . n 
A 1 69  LEU 69  615 615 LEU LEU A . n 
A 1 70  SER 70  616 616 SER SER A . n 
A 1 71  ARG 71  617 617 ARG ARG A . n 
A 1 72  SER 72  618 618 SER SER A . n 
A 1 73  GLN 73  619 619 GLN GLN A . n 
A 1 74  PRO 74  620 620 PRO PRO A . n 
A 1 75  VAL 75  621 621 VAL VAL A . n 
A 1 76  MET 76  622 622 MET MET A . n 
A 1 77  LYS 77  623 623 LYS LYS A . n 
A 1 78  VAL 78  624 624 VAL VAL A . n 
A 1 79  ALA 79  625 625 ALA ALA A . n 
A 1 80  VAL 80  626 626 VAL VAL A . n 
A 1 81  LYS 81  627 627 LYS LYS A . n 
A 1 82  MET 82  628 628 MET MET A . n 
A 1 83  LEU 83  629 629 LEU LEU A . n 
A 1 84  LYS 84  630 630 LYS LYS A . n 
A 1 85  PRO 85  631 631 PRO PRO A . n 
A 1 86  THR 86  632 632 THR THR A . n 
A 1 87  ALA 87  633 633 ALA ALA A . n 
A 1 88  ARG 88  634 634 ARG ARG A . n 
A 1 89  SER 89  635 635 SER SER A . n 
A 1 90  SER 90  636 636 SER SER A . n 
A 1 91  GLU 91  637 637 GLU GLU A . n 
A 1 92  LYS 92  638 638 LYS LYS A . n 
A 1 93  GLN 93  639 639 GLN GLN A . n 
A 1 94  ALA 94  640 640 ALA ALA A . n 
A 1 95  LEU 95  641 641 LEU LEU A . n 
A 1 96  MET 96  642 642 MET MET A . n 
A 1 97  SER 97  643 643 SER SER A . n 
A 1 98  GLU 98  644 644 GLU GLU A . n 
A 1 99  LEU 99  645 645 LEU LEU A . n 
A 1 100 LYS 100 646 646 LYS LYS A . n 
A 1 101 ILE 101 647 647 ILE ILE A . n 
A 1 102 MET 102 648 648 MET MET A . n 
A 1 103 THR 103 649 649 THR THR A . n 
A 1 104 HIS 104 650 650 HIS HIS A . n 
A 1 105 LEU 105 651 651 LEU LEU A . n 
A 1 106 GLY 106 652 652 GLY GLY A . n 
A 1 107 PRO 107 653 653 PRO PRO A . n 
A 1 108 HIS 108 654 654 HIS HIS A . n 
A 1 109 LEU 109 655 655 LEU LEU A . n 
A 1 110 ASN 110 656 656 ASN ASN A . n 
A 1 111 ILE 111 657 657 ILE ILE A . n 
A 1 112 VAL 112 658 658 VAL VAL A . n 
A 1 113 ASN 113 659 659 ASN ASN A . n 
A 1 114 LEU 114 660 660 LEU LEU A . n 
A 1 115 LEU 115 661 661 LEU LEU A . n 
A 1 116 GLY 116 662 662 GLY GLY A . n 
A 1 117 ALA 117 663 663 ALA ALA A . n 
A 1 118 CYS 118 664 664 CYS CYS A . n 
A 1 119 THR 119 665 665 THR THR A . n 
A 1 120 LYS 120 666 666 LYS LYS A . n 
A 1 121 SER 121 667 667 SER SER A . n 
A 1 122 GLY 122 668 668 GLY GLY A . n 
A 1 123 PRO 123 669 669 PRO PRO A . n 
A 1 124 ILE 124 670 670 ILE ILE A . n 
A 1 125 TYR 125 671 671 TYR TYR A . n 
A 1 126 ILE 126 672 672 ILE ILE A . n 
A 1 127 ILE 127 673 673 ILE ILE A . n 
A 1 128 ILE 128 674 674 ILE ILE A . n 
A 1 129 GLU 129 675 675 GLU GLU A . n 
A 1 130 TYR 130 676 676 TYR TYR A . n 
A 1 131 CYS 131 677 677 CYS CYS A . n 
A 1 132 PHE 132 678 678 PHE PHE A . n 
A 1 133 TYR 133 679 679 TYR TYR A . n 
A 1 134 GLY 134 680 680 GLY GLY A . n 
A 1 135 ASP 135 681 681 ASP ASP A . n 
A 1 136 LEU 136 682 682 LEU LEU A . n 
A 1 137 VAL 137 683 683 VAL VAL A . n 
A 1 138 ASN 138 684 684 ASN ASN A . n 
A 1 139 TYR 139 685 685 TYR TYR A . n 
A 1 140 LEU 140 686 686 LEU LEU A . n 
A 1 141 HIS 141 687 687 HIS HIS A . n 
A 1 142 LYS 142 688 688 LYS LYS A . n 
A 1 143 ASN 143 689 689 ASN ASN A . n 
A 1 144 ARG 144 690 690 ARG ARG A . n 
A 1 145 ASP 145 691 691 ASP ASP A . n 
A 1 146 SER 146 692 692 SER SER A . n 
A 1 147 PHE 147 693 693 PHE PHE A . n 
A 1 148 LEU 148 694 694 LEU LEU A . n 
A 1 149 SER 149 767 ?   ?   ?   A . n 
A 1 150 HIS 150 768 ?   ?   ?   A . n 
A 1 151 LYS 151 769 ?   ?   ?   A . n 
A 1 152 LYS 152 770 ?   ?   ?   A . n 
A 1 153 LYS 153 771 ?   ?   ?   A . n 
A 1 154 SER 154 772 ?   ?   ?   A . n 
A 1 155 MET 155 773 ?   ?   ?   A . n 
A 1 156 LEU 156 774 ?   ?   ?   A . n 
A 1 157 ASP 157 775 ?   ?   ?   A . n 
A 1 158 SER 158 776 ?   ?   ?   A . n 
A 1 159 GLU 159 777 ?   ?   ?   A . n 
A 1 160 VAL 160 778 ?   ?   ?   A . n 
A 1 161 LYS 161 779 ?   ?   ?   A . n 
A 1 162 ASN 162 780 ?   ?   ?   A . n 
A 1 163 LEU 163 781 ?   ?   ?   A . n 
A 1 164 LEU 164 782 ?   ?   ?   A . n 
A 1 165 SER 165 783 ?   ?   ?   A . n 
A 1 166 ASP 166 784 ?   ?   ?   A . n 
A 1 167 ASP 167 785 ?   ?   ?   A . n 
A 1 168 ASN 168 786 ?   ?   ?   A . n 
A 1 169 SER 169 787 ?   ?   ?   A . n 
A 1 170 GLU 170 788 ?   ?   ?   A . n 
A 1 171 GLY 171 789 789 GLY GLY A . n 
A 1 172 LEU 172 790 790 LEU LEU A . n 
A 1 173 THR 173 791 791 THR THR A . n 
A 1 174 LEU 174 792 792 LEU LEU A . n 
A 1 175 LEU 175 793 793 LEU LEU A . n 
A 1 176 ASP 176 794 794 ASP ASP A . n 
A 1 177 LEU 177 795 795 LEU LEU A . n 
A 1 178 LEU 178 796 796 LEU LEU A . n 
A 1 179 SER 179 797 797 SER SER A . n 
A 1 180 PHE 180 798 798 PHE PHE A . n 
A 1 181 THR 181 799 799 THR THR A . n 
A 1 182 TYR 182 800 800 TYR TYR A . n 
A 1 183 GLN 183 801 801 GLN GLN A . n 
A 1 184 VAL 184 802 802 VAL VAL A . n 
A 1 185 ALA 185 803 803 ALA ALA A . n 
A 1 186 ARG 186 804 804 ARG ARG A . n 
A 1 187 GLY 187 805 805 GLY GLY A . n 
A 1 188 MET 188 806 806 MET MET A . n 
A 1 189 GLU 189 807 807 GLU GLU A . n 
A 1 190 PHE 190 808 808 PHE PHE A . n 
A 1 191 LEU 191 809 809 LEU LEU A . n 
A 1 192 ALA 192 810 810 ALA ALA A . n 
A 1 193 SER 193 811 811 SER SER A . n 
A 1 194 LYS 194 812 812 LYS LYS A . n 
A 1 195 ASN 195 813 813 ASN ASN A . n 
A 1 196 CYS 196 814 814 CYS CYS A . n 
A 1 197 VAL 197 815 815 VAL VAL A . n 
A 1 198 HIS 198 816 816 HIS HIS A . n 
A 1 199 ARG 199 817 817 ARG ARG A . n 
A 1 200 ASP 200 818 818 ASP ASP A . n 
A 1 201 LEU 201 819 819 LEU LEU A . n 
A 1 202 ALA 202 820 820 ALA ALA A . n 
A 1 203 ALA 203 821 821 ALA ALA A . n 
A 1 204 ARG 204 822 822 ARG ARG A . n 
A 1 205 ASN 205 823 823 ASN ASN A . n 
A 1 206 VAL 206 824 824 VAL VAL A . n 
A 1 207 LEU 207 825 825 LEU LEU A . n 
A 1 208 LEU 208 826 826 LEU LEU A . n 
A 1 209 ALA 209 827 827 ALA ALA A . n 
A 1 210 GLN 210 828 828 GLN GLN A . n 
A 1 211 GLY 211 829 829 GLY GLY A . n 
A 1 212 LYS 212 830 830 LYS LYS A . n 
A 1 213 ILE 213 831 831 ILE ILE A . n 
A 1 214 VAL 214 832 832 VAL VAL A . n 
A 1 215 LYS 215 833 833 LYS LYS A . n 
A 1 216 ILE 216 834 834 ILE ILE A . n 
A 1 217 CYS 217 835 835 CYS CYS A . n 
A 1 218 ASP 218 836 836 ASP ASP A . n 
A 1 219 PHE 219 837 837 PHE PHE A . n 
A 1 220 GLY 220 838 838 GLY GLY A . n 
A 1 221 LEU 221 839 839 LEU LEU A . n 
A 1 222 ALA 222 840 840 ALA ALA A . n 
A 1 223 ARG 223 841 841 ARG ARG A . n 
A 1 224 ASP 224 842 842 ASP ASP A . n 
A 1 225 ILE 225 843 843 ILE ILE A . n 
A 1 226 MET 226 844 844 MET MET A . n 
A 1 227 HIS 227 845 845 HIS HIS A . n 
A 1 228 ASP 228 846 846 ASP ASP A . n 
A 1 229 SER 229 847 847 SER SER A . n 
A 1 230 ASN 230 848 848 ASN ASN A . n 
A 1 231 TYR 231 849 849 TYR TYR A . n 
A 1 232 VAL 232 850 850 VAL VAL A . n 
A 1 233 SER 233 851 851 SER SER A . n 
A 1 234 LYS 234 852 852 LYS LYS A . n 
A 1 235 GLY 235 853 853 GLY GLY A . n 
A 1 236 SER 236 854 854 SER SER A . n 
A 1 237 THR 237 855 855 THR THR A . n 
A 1 238 PHE 238 856 856 PHE PHE A . n 
A 1 239 LEU 239 857 857 LEU LEU A . n 
A 1 240 PRO 240 858 858 PRO PRO A . n 
A 1 241 VAL 241 859 859 VAL VAL A . n 
A 1 242 LYS 242 860 860 LYS LYS A . n 
A 1 243 TRP 243 861 861 TRP TRP A . n 
A 1 244 MET 244 862 862 MET MET A . n 
A 1 245 ALA 245 863 863 ALA ALA A . n 
A 1 246 PRO 246 864 864 PRO PRO A . n 
A 1 247 GLU 247 865 865 GLU GLU A . n 
A 1 248 SER 248 866 866 SER SER A . n 
A 1 249 ILE 249 867 867 ILE ILE A . n 
A 1 250 PHE 250 868 868 PHE PHE A . n 
A 1 251 ASP 251 869 869 ASP ASP A . n 
A 1 252 ASN 252 870 870 ASN ASN A . n 
A 1 253 LEU 253 871 871 LEU LEU A . n 
A 1 254 TYR 254 872 872 TYR TYR A . n 
A 1 255 THR 255 873 873 THR THR A . n 
A 1 256 THR 256 874 874 THR THR A . n 
A 1 257 LEU 257 875 875 LEU LEU A . n 
A 1 258 SER 258 876 876 SER SER A . n 
A 1 259 ASP 259 877 877 ASP ASP A . n 
A 1 260 VAL 260 878 878 VAL VAL A . n 
A 1 261 TRP 261 879 879 TRP TRP A . n 
A 1 262 SER 262 880 880 SER SER A . n 
A 1 263 TYR 263 881 881 TYR TYR A . n 
A 1 264 GLY 264 882 882 GLY GLY A . n 
A 1 265 ILE 265 883 883 ILE ILE A . n 
A 1 266 LEU 266 884 884 LEU LEU A . n 
A 1 267 LEU 267 885 885 LEU LEU A . n 
A 1 268 TRP 268 886 886 TRP TRP A . n 
A 1 269 GLU 269 887 887 GLU GLU A . n 
A 1 270 ILE 270 888 888 ILE ILE A . n 
A 1 271 PHE 271 889 889 PHE PHE A . n 
A 1 272 SER 272 890 890 SER SER A . n 
A 1 273 LEU 273 891 891 LEU LEU A . n 
A 1 274 GLY 274 892 892 GLY GLY A . n 
A 1 275 GLY 275 893 893 GLY GLY A . n 
A 1 276 THR 276 894 894 THR THR A . n 
A 1 277 PRO 277 895 895 PRO PRO A . n 
A 1 278 TYR 278 896 896 TYR TYR A . n 
A 1 279 PRO 279 897 897 PRO PRO A . n 
A 1 280 GLY 280 898 898 GLY GLY A . n 
A 1 281 MET 281 899 899 MET MET A . n 
A 1 282 MET 282 900 900 MET MET A . n 
A 1 283 VAL 283 901 901 VAL VAL A . n 
A 1 284 ASP 284 902 902 ASP ASP A . n 
A 1 285 SER 285 903 903 SER SER A . n 
A 1 286 THR 286 904 904 THR THR A . n 
A 1 287 PHE 287 905 905 PHE PHE A . n 
A 1 288 TYR 288 906 906 TYR TYR A . n 
A 1 289 ASN 289 907 907 ASN ASN A . n 
A 1 290 LYS 290 908 908 LYS LYS A . n 
A 1 291 ILE 291 909 909 ILE ILE A . n 
A 1 292 LYS 292 910 910 LYS LYS A . n 
A 1 293 SER 293 911 911 SER SER A . n 
A 1 294 GLY 294 912 912 GLY GLY A . n 
A 1 295 TYR 295 913 913 TYR TYR A . n 
A 1 296 ARG 296 914 914 ARG ARG A . n 
A 1 297 MET 297 915 915 MET MET A . n 
A 1 298 ALA 298 916 916 ALA ALA A . n 
A 1 299 LYS 299 917 917 LYS LYS A . n 
A 1 300 PRO 300 918 918 PRO PRO A . n 
A 1 301 ASP 301 919 919 ASP ASP A . n 
A 1 302 HIS 302 920 920 HIS HIS A . n 
A 1 303 ALA 303 921 921 ALA ALA A . n 
A 1 304 THR 304 922 922 THR THR A . n 
A 1 305 SER 305 923 923 SER SER A . n 
A 1 306 GLU 306 924 924 GLU GLU A . n 
A 1 307 VAL 307 925 925 VAL VAL A . n 
A 1 308 TYR 308 926 926 TYR TYR A . n 
A 1 309 GLU 309 927 927 GLU GLU A . n 
A 1 310 ILE 310 928 928 ILE ILE A . n 
A 1 311 MET 311 929 929 MET MET A . n 
A 1 312 VAL 312 930 930 VAL VAL A . n 
A 1 313 LYS 313 931 931 LYS LYS A . n 
A 1 314 CYS 314 932 932 CYS CYS A . n 
A 1 315 TRP 315 933 933 TRP TRP A . n 
A 1 316 ASN 316 934 934 ASN ASN A . n 
A 1 317 SER 317 935 935 SER SER A . n 
A 1 318 GLU 318 936 936 GLU GLU A . n 
A 1 319 PRO 319 937 937 PRO PRO A . n 
A 1 320 GLU 320 938 938 GLU GLU A . n 
A 1 321 LYS 321 939 939 LYS LYS A . n 
A 1 322 ARG 322 940 940 ARG ARG A . n 
A 1 323 PRO 323 941 941 PRO PRO A . n 
A 1 324 SER 324 942 942 SER SER A . n 
A 1 325 PHE 325 943 943 PHE PHE A . n 
A 1 326 TYR 326 944 944 TYR TYR A . n 
A 1 327 HIS 327 945 945 HIS HIS A . n 
A 1 328 LEU 328 946 946 LEU LEU A . n 
A 1 329 SER 329 947 947 SER SER A . n 
A 1 330 GLU 330 948 948 GLU GLU A . n 
A 1 331 ILE 331 949 949 ILE ILE A . n 
A 1 332 VAL 332 950 950 VAL VAL A . n 
A 1 333 GLU 333 951 951 GLU GLU A . n 
A 1 334 ASN 334 952 952 ASN ASN A . n 
A 1 335 LEU 335 953 953 LEU LEU A . n 
A 1 336 LEU 336 954 954 LEU LEU A . n 
A 1 337 PRO 337 955 955 PRO PRO A . n 
A 1 338 GLY 338 956 956 GLY GLY A . n 
A 1 339 GLN 339 957 957 GLN GLN A . n 
A 1 340 TYR 340 958 958 TYR TYR A . n 
A 1 341 LYS 341 959 ?   ?   ?   A . n 
A 1 342 LYS 342 960 ?   ?   ?   A . n 
A 1 343 SER 343 961 ?   ?   ?   A . n 
A 1 344 TYR 344 962 ?   ?   ?   A . n 
A 1 345 GLU 345 963 ?   ?   ?   A . n 
A 1 346 LYS 346 964 ?   ?   ?   A . n 
A 1 347 ILE 347 965 ?   ?   ?   A . n 
A 1 348 HIS 348 966 ?   ?   ?   A . n 
A 1 349 LEU 349 967 ?   ?   ?   A . n 
A 1 350 ASP 350 968 ?   ?   ?   A . n 
A 1 351 PHE 351 969 ?   ?   ?   A . n 
A 1 352 LEU 352 970 ?   ?   ?   A . n 
A 1 353 LYS 353 971 ?   ?   ?   A . n 
A 1 354 SER 354 972 ?   ?   ?   A . n 
A 1 355 ASP 355 973 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1IRC 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1IRC 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 A1IRC 1  1001 1001 A1IRC LIG A . 
C 3 HOH   1  1101 353  HOH   HOH A . 
C 3 HOH   2  1102 336  HOH   HOH A . 
C 3 HOH   3  1103 77   HOH   HOH A . 
C 3 HOH   4  1104 14   HOH   HOH A . 
C 3 HOH   5  1105 382  HOH   HOH A . 
C 3 HOH   6  1106 23   HOH   HOH A . 
C 3 HOH   7  1107 292  HOH   HOH A . 
C 3 HOH   8  1108 372  HOH   HOH A . 
C 3 HOH   9  1109 34   HOH   HOH A . 
C 3 HOH   10 1110 79   HOH   HOH A . 
C 3 HOH   11 1111 141  HOH   HOH A . 
C 3 HOH   12 1112 29   HOH   HOH A . 
C 3 HOH   13 1113 48   HOH   HOH A . 
C 3 HOH   14 1114 24   HOH   HOH A . 
C 3 HOH   15 1115 60   HOH   HOH A . 
C 3 HOH   16 1116 10   HOH   HOH A . 
C 3 HOH   17 1117 107  HOH   HOH A . 
C 3 HOH   18 1118 44   HOH   HOH A . 
C 3 HOH   19 1119 25   HOH   HOH A . 
C 3 HOH   20 1120 31   HOH   HOH A . 
C 3 HOH   21 1121 54   HOH   HOH A . 
C 3 HOH   22 1122 36   HOH   HOH A . 
C 3 HOH   23 1123 101  HOH   HOH A . 
C 3 HOH   24 1124 30   HOH   HOH A . 
C 3 HOH   25 1125 110  HOH   HOH A . 
C 3 HOH   26 1126 173  HOH   HOH A . 
C 3 HOH   27 1127 95   HOH   HOH A . 
C 3 HOH   28 1128 19   HOH   HOH A . 
C 3 HOH   29 1129 20   HOH   HOH A . 
C 3 HOH   30 1130 281  HOH   HOH A . 
C 3 HOH   31 1131 35   HOH   HOH A . 
C 3 HOH   32 1132 61   HOH   HOH A . 
C 3 HOH   33 1133 96   HOH   HOH A . 
C 3 HOH   34 1134 37   HOH   HOH A . 
C 3 HOH   35 1135 49   HOH   HOH A . 
C 3 HOH   36 1136 341  HOH   HOH A . 
C 3 HOH   37 1137 27   HOH   HOH A . 
C 3 HOH   38 1138 252  HOH   HOH A . 
C 3 HOH   39 1139 43   HOH   HOH A . 
C 3 HOH   40 1140 3    HOH   HOH A . 
C 3 HOH   41 1141 2    HOH   HOH A . 
C 3 HOH   42 1142 69   HOH   HOH A . 
C 3 HOH   43 1143 383  HOH   HOH A . 
C 3 HOH   44 1144 116  HOH   HOH A . 
C 3 HOH   45 1145 21   HOH   HOH A . 
C 3 HOH   46 1146 329  HOH   HOH A . 
C 3 HOH   47 1147 11   HOH   HOH A . 
C 3 HOH   48 1148 51   HOH   HOH A . 
C 3 HOH   49 1149 188  HOH   HOH A . 
C 3 HOH   50 1150 73   HOH   HOH A . 
C 3 HOH   51 1151 18   HOH   HOH A . 
C 3 HOH   52 1152 52   HOH   HOH A . 
C 3 HOH   53 1153 66   HOH   HOH A . 
C 3 HOH   54 1154 64   HOH   HOH A . 
C 3 HOH   55 1155 91   HOH   HOH A . 
C 3 HOH   56 1156 215  HOH   HOH A . 
C 3 HOH   57 1157 45   HOH   HOH A . 
C 3 HOH   58 1158 114  HOH   HOH A . 
C 3 HOH   59 1159 97   HOH   HOH A . 
C 3 HOH   60 1160 358  HOH   HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ARG 585 ? CG  ? A ARG 39  CG  
2  1 Y 1 A ARG 585 ? CD  ? A ARG 39  CD  
3  1 Y 1 A ARG 585 ? NE  ? A ARG 39  NE  
4  1 Y 1 A ARG 585 ? CZ  ? A ARG 39  CZ  
5  1 Y 1 A ARG 585 ? NH1 ? A ARG 39  NH1 
6  1 Y 1 A ARG 585 ? NH2 ? A ARG 39  NH2 
7  1 Y 1 A PHE 604 ? CG  ? A PHE 58  CG  
8  1 Y 1 A PHE 604 ? CD1 ? A PHE 58  CD1 
9  1 Y 1 A PHE 604 ? CD2 ? A PHE 58  CD2 
10 1 Y 1 A PHE 604 ? CE1 ? A PHE 58  CE1 
11 1 Y 1 A PHE 604 ? CE2 ? A PHE 58  CE2 
12 1 Y 1 A PHE 604 ? CZ  ? A PHE 58  CZ  
13 1 Y 1 A ARG 617 ? CG  ? A ARG 71  CG  
14 1 Y 1 A ARG 617 ? CD  ? A ARG 71  CD  
15 1 Y 1 A ARG 617 ? NE  ? A ARG 71  NE  
16 1 Y 1 A ARG 617 ? CZ  ? A ARG 71  CZ  
17 1 Y 1 A ARG 617 ? NH1 ? A ARG 71  NH1 
18 1 Y 1 A ARG 617 ? NH2 ? A ARG 71  NH2 
19 1 Y 1 A LYS 638 ? CG  ? A LYS 92  CG  
20 1 Y 1 A LYS 638 ? CD  ? A LYS 92  CD  
21 1 Y 1 A LYS 638 ? CE  ? A LYS 92  CE  
22 1 Y 1 A LYS 638 ? NZ  ? A LYS 92  NZ  
23 1 Y 1 A GLN 639 ? CG  ? A GLN 93  CG  
24 1 Y 1 A GLN 639 ? CD  ? A GLN 93  CD  
25 1 Y 1 A GLN 639 ? OE1 ? A GLN 93  OE1 
26 1 Y 1 A GLN 639 ? NE2 ? A GLN 93  NE2 
27 1 Y 1 A LYS 646 ? CG  ? A LYS 100 CG  
28 1 Y 1 A LYS 646 ? CD  ? A LYS 100 CD  
29 1 Y 1 A LYS 646 ? CE  ? A LYS 100 CE  
30 1 Y 1 A LYS 646 ? NZ  ? A LYS 100 NZ  
31 1 Y 1 A LEU 694 ? CG  ? A LEU 148 CG  
32 1 Y 1 A LEU 694 ? CD1 ? A LEU 148 CD1 
33 1 Y 1 A LEU 694 ? CD2 ? A LEU 148 CD2 
34 1 Y 1 A GLN 828 ? CG  ? A GLN 210 CG  
35 1 Y 1 A GLN 828 ? CD  ? A GLN 210 CD  
36 1 Y 1 A GLN 828 ? OE1 ? A GLN 210 OE1 
37 1 Y 1 A GLN 828 ? NE2 ? A GLN 210 NE2 
38 1 Y 1 A LEU 871 ? CG  ? A LEU 253 CG  
39 1 Y 1 A LEU 871 ? CD1 ? A LEU 253 CD1 
40 1 Y 1 A LEU 871 ? CD2 ? A LEU 253 CD2 
41 1 Y 1 A GLU 927 ? CG  ? A GLU 309 CG  
42 1 Y 1 A GLU 927 ? CD  ? A GLU 309 CD  
43 1 Y 1 A GLU 927 ? OE1 ? A GLU 309 OE1 
44 1 Y 1 A GLU 927 ? OE2 ? A GLU 309 OE2 
45 1 Y 1 A GLU 936 ? CG  ? A GLU 318 CG  
46 1 Y 1 A GLU 936 ? CD  ? A GLU 318 CD  
47 1 Y 1 A GLU 936 ? OE1 ? A GLU 318 OE1 
48 1 Y 1 A GLU 936 ? OE2 ? A GLU 318 OE2 
49 1 Y 1 A GLU 938 ? CG  ? A GLU 320 CG  
50 1 Y 1 A GLU 938 ? CD  ? A GLU 320 CD  
51 1 Y 1 A GLU 938 ? OE1 ? A GLU 320 OE1 
52 1 Y 1 A GLU 938 ? OE2 ? A GLU 320 OE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? 1.14_3260 1 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.14_3260 2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XSCALE ? ? ? .         3 
? 'model building' ? ? ? ? ? ? ? ? ? ? ? Coot   ? ? ? .         4 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .         5 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9GZH 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     135.920 
_cell.length_a_esd                 ? 
_cell.length_b                     135.920 
_cell.length_b_esd                 ? 
_cell.length_c                     34.690 
_cell.length_c_esd                 ? 
_cell.volume                       555011.093 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9GZH 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                168 
_symmetry.space_group_name_Hall            'P 6' 
_symmetry.space_group_name_H-M             'P 6' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9GZH 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.29 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          46.23 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '5 mg/mL, 18% PEG3350, 100 mM KCl' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-08-23 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    'SI (III)' 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.999 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SLS BEAMLINE X10SA' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.999 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   X10SA 
_diffrn_source.pdbx_synchrotron_site       SLS 
# 
_reflns.B_iso_Wilson_estimate                          56.06 
_reflns.entry_id                                       9GZH 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.20 
_reflns.d_resolution_low                               33.98 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     19061 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                20.00 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          19.17 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.99 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.20 
_reflns_shell.d_res_low                                     2.32 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.89 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2353 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.85 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               67.14 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9GZH 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.20 
_refine.ls_d_res_low                             33.98 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     19061 
_refine.ls_number_reflns_R_free                  953 
_refine.ls_number_reflns_R_work                  18108 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.99 
_refine.ls_percent_reflns_R_free                 5.00 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1834 
_refine.ls_R_factor_R_free                       0.2147 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1818 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.37 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 24.7002 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2605 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.20 
_refine_hist.d_res_low                        33.98 
_refine_hist.number_atoms_solvent             60 
_refine_hist.number_atoms_total               2277 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2181 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         36 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0029  ? 2284 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.6299  ? 3101 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0441  ? 339  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0031  ? 386  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 10.5399 ? 1329 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.20 2.32  . . 135 2566 100.00 . . . . 0.2512 . . . . . . . . . . . 0.2933 
'X-RAY DIFFRACTION' 2.32 2.46  . . 134 2549 100.00 . . . . 0.2327 . . . . . . . . . . . 0.2547 
'X-RAY DIFFRACTION' 2.46 2.65  . . 135 2545 100.00 . . . . 0.2419 . . . . . . . . . . . 0.2925 
'X-RAY DIFFRACTION' 2.65 2.92  . . 135 2565 100.00 . . . . 0.2300 . . . . . . . . . . . 0.2398 
'X-RAY DIFFRACTION' 2.92 3.34  . . 136 2586 99.96  . . . . 0.2121 . . . . . . . . . . . 0.2690 
'X-RAY DIFFRACTION' 3.34 4.21  . . 136 2598 100.00 . . . . 0.1659 . . . . . . . . . . . 0.1864 
'X-RAY DIFFRACTION' 4.21 33.98 . . 142 2699 100.00 . . . . 0.1526 . . . . . . . . . . . 0.1870 
# 
_struct.entry_id                     9GZH 
_struct.title                        'PDGFRA-T674I in complex with covalent ponatinib derivative 19' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9GZH 
_struct_keywords.text            
;platelet-derived growth factor receptor alpha, PDGFRA, GIST, gastrointestinal stromal tumor, ponatinib, gatekeeper mutation, covalent drugs, drug resistance, resistance mutation, secondary mutation, TRANSFERASE
;
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    PGFRA_HUMAN 
_struct_ref.pdbx_db_accession          P16234 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;KQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAVKML
KPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSHHPEKPKKELDIFG
LNPADESTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLLSDDNSEG
LTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFD
NLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEI
VENLLPGQYKKSYEKIHLDFLKSD
;
_struct_ref.pdbx_align_begin           550 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9GZH 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 4 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 355 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P16234 
_struct_ref_seq.db_align_beg                  550 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  973 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       550 
_struct_ref_seq.pdbx_auth_seq_align_end       973 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9GZH GLY A 1   ? UNP P16234 ?   ?   'expression tag'      547 1  
1 9GZH PRO A 2   ? UNP P16234 ?   ?   'expression tag'      548 2  
1 9GZH GLY A 3   ? UNP P16234 ?   ?   'expression tag'      549 3  
1 9GZH ILE A 128 ? UNP P16234 THR 674 'engineered mutation' 674 4  
1 9GZH ?   A ?   ? UNP P16234 HIS 697 deletion              ?   5  
1 9GZH ?   A ?   ? UNP P16234 PRO 698 deletion              ?   6  
1 9GZH ?   A ?   ? UNP P16234 GLU 699 deletion              ?   7  
1 9GZH ?   A ?   ? UNP P16234 LYS 700 deletion              ?   8  
1 9GZH ?   A ?   ? UNP P16234 PRO 701 deletion              ?   9  
1 9GZH ?   A ?   ? UNP P16234 LYS 702 deletion              ?   10 
1 9GZH ?   A ?   ? UNP P16234 LYS 703 deletion              ?   11 
1 9GZH ?   A ?   ? UNP P16234 GLU 704 deletion              ?   12 
1 9GZH ?   A ?   ? UNP P16234 LEU 705 deletion              ?   13 
1 9GZH ?   A ?   ? UNP P16234 ASP 706 deletion              ?   14 
1 9GZH ?   A ?   ? UNP P16234 ILE 707 deletion              ?   15 
1 9GZH ?   A ?   ? UNP P16234 PHE 708 deletion              ?   16 
1 9GZH ?   A ?   ? UNP P16234 GLY 709 deletion              ?   17 
1 9GZH ?   A ?   ? UNP P16234 LEU 710 deletion              ?   18 
1 9GZH ?   A ?   ? UNP P16234 ASN 711 deletion              ?   19 
1 9GZH ?   A ?   ? UNP P16234 PRO 712 deletion              ?   20 
1 9GZH ?   A ?   ? UNP P16234 ALA 713 deletion              ?   21 
1 9GZH ?   A ?   ? UNP P16234 ASP 714 deletion              ?   22 
1 9GZH ?   A ?   ? UNP P16234 GLU 715 deletion              ?   23 
1 9GZH ?   A ?   ? UNP P16234 SER 716 deletion              ?   24 
1 9GZH ?   A ?   ? UNP P16234 THR 717 deletion              ?   25 
1 9GZH ?   A ?   ? UNP P16234 ARG 718 deletion              ?   26 
1 9GZH ?   A ?   ? UNP P16234 SER 719 deletion              ?   27 
1 9GZH ?   A ?   ? UNP P16234 TYR 720 deletion              ?   28 
1 9GZH ?   A ?   ? UNP P16234 VAL 721 deletion              ?   29 
1 9GZH ?   A ?   ? UNP P16234 ILE 722 deletion              ?   30 
1 9GZH ?   A ?   ? UNP P16234 LEU 723 deletion              ?   31 
1 9GZH ?   A ?   ? UNP P16234 SER 724 deletion              ?   32 
1 9GZH ?   A ?   ? UNP P16234 PHE 725 deletion              ?   33 
1 9GZH ?   A ?   ? UNP P16234 GLU 726 deletion              ?   34 
1 9GZH ?   A ?   ? UNP P16234 ASN 727 deletion              ?   35 
1 9GZH ?   A ?   ? UNP P16234 ASN 728 deletion              ?   36 
1 9GZH ?   A ?   ? UNP P16234 GLY 729 deletion              ?   37 
1 9GZH ?   A ?   ? UNP P16234 ASP 730 deletion              ?   38 
1 9GZH ?   A ?   ? UNP P16234 TYR 731 deletion              ?   39 
1 9GZH ?   A ?   ? UNP P16234 MET 732 deletion              ?   40 
1 9GZH ?   A ?   ? UNP P16234 ASP 733 deletion              ?   41 
1 9GZH ?   A ?   ? UNP P16234 MET 734 deletion              ?   42 
1 9GZH ?   A ?   ? UNP P16234 LYS 735 deletion              ?   43 
1 9GZH ?   A ?   ? UNP P16234 GLN 736 deletion              ?   44 
1 9GZH ?   A ?   ? UNP P16234 ALA 737 deletion              ?   45 
1 9GZH ?   A ?   ? UNP P16234 ASP 738 deletion              ?   46 
1 9GZH ?   A ?   ? UNP P16234 THR 739 deletion              ?   47 
1 9GZH ?   A ?   ? UNP P16234 THR 740 deletion              ?   48 
1 9GZH ?   A ?   ? UNP P16234 GLN 741 deletion              ?   49 
1 9GZH ?   A ?   ? UNP P16234 TYR 742 deletion              ?   50 
1 9GZH ?   A ?   ? UNP P16234 VAL 743 deletion              ?   51 
1 9GZH ?   A ?   ? UNP P16234 PRO 744 deletion              ?   52 
1 9GZH ?   A ?   ? UNP P16234 MET 745 deletion              ?   53 
1 9GZH ?   A ?   ? UNP P16234 LEU 746 deletion              ?   54 
1 9GZH ?   A ?   ? UNP P16234 GLU 747 deletion              ?   55 
1 9GZH ?   A ?   ? UNP P16234 ARG 748 deletion              ?   56 
1 9GZH ?   A ?   ? UNP P16234 LYS 749 deletion              ?   57 
1 9GZH ?   A ?   ? UNP P16234 GLU 750 deletion              ?   58 
1 9GZH ?   A ?   ? UNP P16234 VAL 751 deletion              ?   59 
1 9GZH ?   A ?   ? UNP P16234 SER 752 deletion              ?   60 
1 9GZH ?   A ?   ? UNP P16234 LYS 753 deletion              ?   61 
1 9GZH ?   A ?   ? UNP P16234 TYR 754 deletion              ?   62 
1 9GZH ?   A ?   ? UNP P16234 SER 755 deletion              ?   63 
1 9GZH ?   A ?   ? UNP P16234 ASP 756 deletion              ?   64 
1 9GZH ?   A ?   ? UNP P16234 ILE 757 deletion              ?   65 
1 9GZH ?   A ?   ? UNP P16234 GLN 758 deletion              ?   66 
1 9GZH ?   A ?   ? UNP P16234 ARG 759 deletion              ?   67 
1 9GZH ?   A ?   ? UNP P16234 SER 760 deletion              ?   68 
1 9GZH ?   A ?   ? UNP P16234 LEU 761 deletion              ?   69 
1 9GZH ?   A ?   ? UNP P16234 TYR 762 deletion              ?   70 
1 9GZH ?   A ?   ? UNP P16234 ASP 763 deletion              ?   71 
1 9GZH ?   A ?   ? UNP P16234 ARG 764 deletion              ?   72 
1 9GZH ?   A ?   ? UNP P16234 PRO 765 deletion              ?   73 
1 9GZH ?   A ?   ? UNP P16234 ALA 766 deletion              ?   74 
1 9GZH ?   A ?   ? UNP P16234 SER 767 deletion              ?   75 
1 9GZH ?   A ?   ? UNP P16234 TYR 768 deletion              ?   76 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 0     ? 
1 MORE         0     ? 
1 'SSA (A^2)'  13190 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 43  ? ASP A 45  ? PRO A 589 ASP A 591 5 ? 3  
HELX_P HELX_P2  AA2 ARG A 88  ? GLY A 106 ? ARG A 634 GLY A 652 1 ? 19 
HELX_P HELX_P3  AA3 ASP A 135 ? ARG A 144 ? ASP A 681 ARG A 690 1 ? 10 
HELX_P HELX_P4  AA4 THR A 173 ? LYS A 194 ? THR A 791 LYS A 812 1 ? 22 
HELX_P HELX_P5  AA5 ALA A 202 ? ARG A 204 ? ALA A 820 ARG A 822 5 ? 3  
HELX_P HELX_P6  AA6 PHE A 219 ? ARG A 223 ? PHE A 837 ARG A 841 5 ? 5  
HELX_P HELX_P7  AA7 PRO A 240 ? MET A 244 ? PRO A 858 MET A 862 5 ? 5  
HELX_P HELX_P8  AA8 ALA A 245 ? ASN A 252 ? ALA A 863 ASN A 870 1 ? 8  
HELX_P HELX_P9  AA9 THR A 255 ? SER A 272 ? THR A 873 SER A 890 1 ? 18 
HELX_P HELX_P10 AB1 ASP A 284 ? SER A 293 ? ASP A 902 SER A 911 1 ? 10 
HELX_P HELX_P11 AB2 THR A 304 ? TRP A 315 ? THR A 922 TRP A 933 1 ? 12 
HELX_P HELX_P12 AB3 GLU A 318 ? ARG A 322 ? GLU A 936 ARG A 940 5 ? 5  
HELX_P HELX_P13 AB4 SER A 324 ? LEU A 336 ? SER A 942 LEU A 954 1 ? 13 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            covale1 
_struct_conn.conn_type_id                  covale 
_struct_conn.pdbx_leaving_atom_flag        none 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            196 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           B 
_struct_conn.ptnr2_label_comp_id           A1IRC 
_struct_conn.ptnr2_label_seq_id            . 
_struct_conn.ptnr2_label_atom_id           C29 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             814 
_struct_conn.ptnr2_auth_asym_id            A 
_struct_conn.ptnr2_auth_comp_id            A1IRC 
_struct_conn.ptnr2_auth_seq_id             1001 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               1.766 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      A1IRC 
_pdbx_modification_feature.label_asym_id                      B 
_pdbx_modification_feature.label_seq_id                       . 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      196 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       A1IRC 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        1001 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       814 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               C29 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                CYS 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        A1IRC 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Covalent chemical modification' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 47  ? SER A 55  ? LEU A 593 SER A 601 
AA1 2 GLY A 59  ? TYR A 67  ? GLY A 605 TYR A 613 
AA1 3 VAL A 75  ? LEU A 83  ? VAL A 621 LEU A 629 
AA1 4 TYR A 125 ? GLU A 129 ? TYR A 671 GLU A 675 
AA1 5 LEU A 114 ? CYS A 118 ? LEU A 660 CYS A 664 
AA2 1 VAL A 206 ? ALA A 209 ? VAL A 824 ALA A 827 
AA2 2 ILE A 213 ? ILE A 216 ? ILE A 831 ILE A 834 
AA3 1 VAL A 232 ? LYS A 234 ? VAL A 850 LYS A 852 
AA3 2 THR A 237 ? LEU A 239 ? THR A 855 LEU A 857 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLY A 50  ? N GLY A 596 O GLU A 63  ? O GLU A 609 
AA1 2 3 N VAL A 62  ? N VAL A 608 O VAL A 80  ? O VAL A 626 
AA1 3 4 N ALA A 79  ? N ALA A 625 O ILE A 128 ? O ILE A 674 
AA1 4 5 O ILE A 127 ? O ILE A 673 N GLY A 116 ? N GLY A 662 
AA2 1 2 N LEU A 207 ? N LEU A 825 O LYS A 215 ? O LYS A 833 
AA3 1 2 N VAL A 232 ? N VAL A 850 O LEU A 239 ? O LEU A 857 
# 
_pdbx_entry_details.entry_id                   9GZH 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   NH2 
_pdbx_validate_close_contact.auth_asym_id_1   A 
_pdbx_validate_close_contact.auth_comp_id_1   ARG 
_pdbx_validate_close_contact.auth_seq_id_1    590 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   O 
_pdbx_validate_close_contact.auth_asym_id_2   A 
_pdbx_validate_close_contact.auth_comp_id_2   PRO 
_pdbx_validate_close_contact.auth_seq_id_2    669 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.06 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ARG A 817 ? ? 74.96   -9.55 
2 1 ASP A 818 ? ? -142.67 39.08 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z     
2 x-y,x,z   
3 y,-x+y,z  
4 -y,x-y,z  
5 -x+y,-x,z 
6 -x,-y,z   
# 
loop_
_pdbx_refine_tls.id 
_pdbx_refine_tls.pdbx_refine_id 
_pdbx_refine_tls.details 
_pdbx_refine_tls.method 
_pdbx_refine_tls.origin_x 
_pdbx_refine_tls.origin_y 
_pdbx_refine_tls.origin_z 
_pdbx_refine_tls.T[1][1] 
_pdbx_refine_tls.T[1][1]_esd 
_pdbx_refine_tls.T[1][2] 
_pdbx_refine_tls.T[1][2]_esd 
_pdbx_refine_tls.T[1][3] 
_pdbx_refine_tls.T[1][3]_esd 
_pdbx_refine_tls.T[2][2] 
_pdbx_refine_tls.T[2][2]_esd 
_pdbx_refine_tls.T[2][3] 
_pdbx_refine_tls.T[2][3]_esd 
_pdbx_refine_tls.T[3][3] 
_pdbx_refine_tls.T[3][3]_esd 
_pdbx_refine_tls.L[1][1] 
_pdbx_refine_tls.L[1][1]_esd 
_pdbx_refine_tls.L[1][2] 
_pdbx_refine_tls.L[1][2]_esd 
_pdbx_refine_tls.L[1][3] 
_pdbx_refine_tls.L[1][3]_esd 
_pdbx_refine_tls.L[2][2] 
_pdbx_refine_tls.L[2][2]_esd 
_pdbx_refine_tls.L[2][3] 
_pdbx_refine_tls.L[2][3]_esd 
_pdbx_refine_tls.L[3][3] 
_pdbx_refine_tls.L[3][3]_esd 
_pdbx_refine_tls.S[1][1] 
_pdbx_refine_tls.S[1][1]_esd 
_pdbx_refine_tls.S[1][2] 
_pdbx_refine_tls.S[1][2]_esd 
_pdbx_refine_tls.S[1][3] 
_pdbx_refine_tls.S[1][3]_esd 
_pdbx_refine_tls.S[2][1] 
_pdbx_refine_tls.S[2][1]_esd 
_pdbx_refine_tls.S[2][2] 
_pdbx_refine_tls.S[2][2]_esd 
_pdbx_refine_tls.S[2][3] 
_pdbx_refine_tls.S[2][3]_esd 
_pdbx_refine_tls.S[3][1] 
_pdbx_refine_tls.S[3][1]_esd 
_pdbx_refine_tls.S[3][2] 
_pdbx_refine_tls.S[3][2]_esd 
_pdbx_refine_tls.S[3][3] 
_pdbx_refine_tls.S[3][3]_esd 
1 'X-RAY DIFFRACTION' ? refined -50.3147006104 6.97687105955  8.9187599804   0.550185689512 ? -0.0905982088612 ? 0.00700967810229 
? 0.393428346662 ? -0.0362500764975 ? 0.583464138069 ? 5.55676148197 ? -3.50784965619  ? 2.36045171632   ? 8.78183394654 ? 
-0.106057090634 ? 5.93060273072 ? 0.164846381884   ? 0.301727072547  ? 0.00312459667093 ? 0.144596101626  ? -0.00244553311635 ? 
-0.616805029817   ? -0.0961475074542 ? 0.598526205574    ? -0.059222851396  ? 
2 'X-RAY DIFFRACTION' ? refined -43.0582203845 -2.37479646193 0.122061617167 0.797601464458 ? 0.0350727462463  ? 0.202551589539   
? 0.642417241486 ? -0.080200216919  ? 0.961460368542 ? 5.34736277865 ? 4.41131861058   ? -0.549032029153 ? 3.95402615774 ? 
0.8245723277    ? 5.56723820996 ? 0.0443506997564  ? 1.43528092586   ? -0.0500236870694 ? -0.858546035842 ? 0.484520250623    ? 
-1.65061257922    ? -0.311876885381  ? 0.86935315992     ? -0.892000673728  ? 
3 'X-RAY DIFFRACTION' ? refined -57.8332404081 -4.27842464559 11.2133889885  0.440768799987 ? 0.0729334671112  ? -0.0299511711073 
? 0.413361609863 ? 0.0122604331156  ? 0.438063445339 ? 4.56920988793 ? 1.85610340693   ? -2.18481866704  ? 6.08260768094 ? 
-1.36366914168  ? 4.50568427295 ? 0.240868776241   ? -0.307510280605 ? 0.315426563899   ? 0.174056003474  ? -0.118908893081   ? 
-0.00670471962507 ? -0.407728925453  ? 0.190877515699    ? -0.106036346704  ? 
4 'X-RAY DIFFRACTION' ? refined -55.026222376  -12.9010745937 8.45946248577  0.475477208552 ? 0.015303404553   ? -0.0109012690752 
? 0.320033297712 ? 0.044666062352   ? 0.306608667684 ? 7.84490240307 ? -0.407484986841 ? -0.242912650324 ? 5.35889262833 ? 
-0.348813160953 ? 2.03264822876 ? -0.140955096469  ? 0.209384594217  ? 0.43661572037    ? -0.119200323415 ? -0.0202836646441  ? 
-0.362754880731   ? -0.0810263622579 ? 0.0231942284149   ? 0.198202212562   ? 
5 'X-RAY DIFFRACTION' ? refined -41.0768128057 -22.7008817634 9.5649737922   0.531533371363 ? 0.0369961866847  ? 0.00225104238219 
? 0.65012661529  ? 0.03099493411    ? 0.6491426915   ? 3.50070305504 ? -1.63258360835  ? 0.12866458745   ? 9.03326811638 ? 
4.10251023849   ? 2.21843519835 ? -0.220056464375  ? 0.209740231325  ? -0.233494355855  ? -0.249930776031 ? 0.234649580763    ? 
-1.35653400236    ? -0.141178894302  ? 0.816799254308    ? -0.104102297975  ? 
6 'X-RAY DIFFRACTION' ? refined -53.8070866809 -28.029973254  12.6044695651  0.576319163973 ? 0.0342497906878  ? -0.0392190163214 
? 0.370205633694 ? 0.0505107154789  ? 0.453143062284 ? 7.35046492825 ? -1.66446879726  ? -0.277728235565 ? 6.37191414962 ? 
0.220943553108  ? 1.25918974193 ? -0.0282514406884 ? -0.293309412799 ? -0.775736024164  ? 0.261268805913  ? 0.142411996869    ? 
-0.0203379162569  ? 0.241560340332   ? -0.00358137600448 ? -0.0748474543736 ? 
7 'X-RAY DIFFRACTION' ? refined -68.0306080057 -22.9171682859 0.979022988026 0.815730098485 ? 0.0359621358182  ? -0.0959852467718 
? 0.714339239432 ? -0.0886889472748 ? 0.72062534896  ? 2.56062741882 ? 0.800961427823  ? -2.89541619368  ? 1.88315096255 ? 
0.427116107488  ? 4.35645138183 ? -0.0696079318317 ? 1.57004624012   ? -0.332609349093  ? -0.419088424457 ? -0.20620493561    ? 
1.0582353211      ? -0.240450710944  ? -0.932509151138   ? 0.0944391559172  ? 
# 
loop_
_pdbx_refine_tls_group.id 
_pdbx_refine_tls_group.pdbx_refine_id 
_pdbx_refine_tls_group.refine_tls_id 
_pdbx_refine_tls_group.beg_label_asym_id 
_pdbx_refine_tls_group.beg_label_seq_id 
_pdbx_refine_tls_group.beg_auth_asym_id 
_pdbx_refine_tls_group.beg_auth_seq_id 
_pdbx_refine_tls_group.beg_PDB_ins_code 
_pdbx_refine_tls_group.end_label_asym_id 
_pdbx_refine_tls_group.end_label_seq_id 
_pdbx_refine_tls_group.end_auth_asym_id 
_pdbx_refine_tls_group.end_auth_seq_id 
_pdbx_refine_tls_group.end_PDB_ins_code 
_pdbx_refine_tls_group.selection 
_pdbx_refine_tls_group.selection_details 
1 'X-RAY DIFFRACTION' 1 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 584 through 634 )
;
2 'X-RAY DIFFRACTION' 2 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 635 through 651 )
;
3 'X-RAY DIFFRACTION' 3 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 652 through 791 )
;
4 'X-RAY DIFFRACTION' 4 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 792 through 849 )
;
5 'X-RAY DIFFRACTION' 5 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 850 through 873 )
;
6 'X-RAY DIFFRACTION' 6 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 874 through 942 )
;
7 'X-RAY DIFFRACTION' 7 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 943 through 957 )
;
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY 547 ? A GLY 1   
2  1 Y 1 A PRO 548 ? A PRO 2   
3  1 Y 1 A GLY 549 ? A GLY 3   
4  1 Y 1 A LYS 550 ? A LYS 4   
5  1 Y 1 A GLN 551 ? A GLN 5   
6  1 Y 1 A LYS 552 ? A LYS 6   
7  1 Y 1 A PRO 553 ? A PRO 7   
8  1 Y 1 A ARG 554 ? A ARG 8   
9  1 Y 1 A TYR 555 ? A TYR 9   
10 1 Y 1 A GLU 556 ? A GLU 10  
11 1 Y 1 A ILE 557 ? A ILE 11  
12 1 Y 1 A ARG 558 ? A ARG 12  
13 1 Y 1 A TRP 559 ? A TRP 13  
14 1 Y 1 A ARG 560 ? A ARG 14  
15 1 Y 1 A VAL 561 ? A VAL 15  
16 1 Y 1 A ILE 562 ? A ILE 16  
17 1 Y 1 A GLU 563 ? A GLU 17  
18 1 Y 1 A SER 564 ? A SER 18  
19 1 Y 1 A ILE 565 ? A ILE 19  
20 1 Y 1 A SER 566 ? A SER 20  
21 1 Y 1 A PRO 567 ? A PRO 21  
22 1 Y 1 A ASP 568 ? A ASP 22  
23 1 Y 1 A GLY 569 ? A GLY 23  
24 1 Y 1 A HIS 570 ? A HIS 24  
25 1 Y 1 A GLU 571 ? A GLU 25  
26 1 Y 1 A TYR 572 ? A TYR 26  
27 1 Y 1 A ILE 573 ? A ILE 27  
28 1 Y 1 A TYR 574 ? A TYR 28  
29 1 Y 1 A VAL 575 ? A VAL 29  
30 1 Y 1 A ASP 576 ? A ASP 30  
31 1 Y 1 A PRO 577 ? A PRO 31  
32 1 Y 1 A MET 578 ? A MET 32  
33 1 Y 1 A GLN 579 ? A GLN 33  
34 1 Y 1 A LEU 580 ? A LEU 34  
35 1 Y 1 A PRO 581 ? A PRO 35  
36 1 Y 1 A TYR 582 ? A TYR 36  
37 1 Y 1 A SER 767 ? A SER 149 
38 1 Y 1 A HIS 768 ? A HIS 150 
39 1 Y 1 A LYS 769 ? A LYS 151 
40 1 Y 1 A LYS 770 ? A LYS 152 
41 1 Y 1 A LYS 771 ? A LYS 153 
42 1 Y 1 A SER 772 ? A SER 154 
43 1 Y 1 A MET 773 ? A MET 155 
44 1 Y 1 A LEU 774 ? A LEU 156 
45 1 Y 1 A ASP 775 ? A ASP 157 
46 1 Y 1 A SER 776 ? A SER 158 
47 1 Y 1 A GLU 777 ? A GLU 159 
48 1 Y 1 A VAL 778 ? A VAL 160 
49 1 Y 1 A LYS 779 ? A LYS 161 
50 1 Y 1 A ASN 780 ? A ASN 162 
51 1 Y 1 A LEU 781 ? A LEU 163 
52 1 Y 1 A LEU 782 ? A LEU 164 
53 1 Y 1 A SER 783 ? A SER 165 
54 1 Y 1 A ASP 784 ? A ASP 166 
55 1 Y 1 A ASP 785 ? A ASP 167 
56 1 Y 1 A ASN 786 ? A ASN 168 
57 1 Y 1 A SER 787 ? A SER 169 
58 1 Y 1 A GLU 788 ? A GLU 170 
59 1 Y 1 A LYS 959 ? A LYS 341 
60 1 Y 1 A LYS 960 ? A LYS 342 
61 1 Y 1 A SER 961 ? A SER 343 
62 1 Y 1 A TYR 962 ? A TYR 344 
63 1 Y 1 A GLU 963 ? A GLU 345 
64 1 Y 1 A LYS 964 ? A LYS 346 
65 1 Y 1 A ILE 965 ? A ILE 347 
66 1 Y 1 A HIS 966 ? A HIS 348 
67 1 Y 1 A LEU 967 ? A LEU 349 
68 1 Y 1 A ASP 968 ? A ASP 350 
69 1 Y 1 A PHE 969 ? A PHE 351 
70 1 Y 1 A LEU 970 ? A LEU 352 
71 1 Y 1 A LYS 971 ? A LYS 353 
72 1 Y 1 A SER 972 ? A SER 354 
73 1 Y 1 A ASP 973 ? A ASP 355 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1IRC C10  C Y N 1   
A1IRC C15  C Y N 2   
A1IRC C20  C Y N 3   
A1IRC C21  C Y N 4   
A1IRC C22  C Y N 5   
A1IRC C24  C Y N 6   
A1IRC C28  C N N 7   
A1IRC C01  C Y N 8   
A1IRC C02  C Y N 9   
A1IRC C03  C Y N 10  
A1IRC C04  C Y N 11  
A1IRC C05  C Y N 12  
A1IRC C06  C Y N 13  
A1IRC C07  C N N 14  
A1IRC C08  C N N 15  
A1IRC C09  C Y N 16  
A1IRC C12  C Y N 17  
A1IRC C14  C Y N 18  
A1IRC C16  C Y N 19  
A1IRC C18  C N N 20  
A1IRC C23  C Y N 21  
A1IRC C25  C Y N 22  
A1IRC C27  C N N 23  
A1IRC C29  C N N 24  
A1IRC C31  C N N 25  
A1IRC C35  C N N 26  
A1IRC F32  F N N 27  
A1IRC F33  F N N 28  
A1IRC F34  F N N 29  
A1IRC N11  N Y N 30  
A1IRC N13  N Y N 31  
A1IRC N17  N Y N 32  
A1IRC N19  N N N 33  
A1IRC N26  N N N 34  
A1IRC O30  O N N 35  
A1IRC O36  O N N 36  
A1IRC H101 H N N 37  
A1IRC H151 H N N 38  
A1IRC H211 H N N 39  
A1IRC H241 H N N 40  
A1IRC H282 H N N 41  
A1IRC H281 H N N 42  
A1IRC H031 H N N 43  
A1IRC H051 H N N 44  
A1IRC H061 H N N 45  
A1IRC H141 H N N 46  
A1IRC H161 H N N 47  
A1IRC H251 H N N 48  
A1IRC H293 H N N 49  
A1IRC H292 H N N 50  
A1IRC H291 H N N 51  
A1IRC H353 H N N 52  
A1IRC H352 H N N 53  
A1IRC H351 H N N 54  
A1IRC H191 H N N 55  
A1IRC H261 H N N 56  
ALA   N    N N N 57  
ALA   CA   C N S 58  
ALA   C    C N N 59  
ALA   O    O N N 60  
ALA   CB   C N N 61  
ALA   OXT  O N N 62  
ALA   H    H N N 63  
ALA   H2   H N N 64  
ALA   HA   H N N 65  
ALA   HB1  H N N 66  
ALA   HB2  H N N 67  
ALA   HB3  H N N 68  
ALA   HXT  H N N 69  
ARG   N    N N N 70  
ARG   CA   C N S 71  
ARG   C    C N N 72  
ARG   O    O N N 73  
ARG   CB   C N N 74  
ARG   CG   C N N 75  
ARG   CD   C N N 76  
ARG   NE   N N N 77  
ARG   CZ   C N N 78  
ARG   NH1  N N N 79  
ARG   NH2  N N N 80  
ARG   OXT  O N N 81  
ARG   H    H N N 82  
ARG   H2   H N N 83  
ARG   HA   H N N 84  
ARG   HB2  H N N 85  
ARG   HB3  H N N 86  
ARG   HG2  H N N 87  
ARG   HG3  H N N 88  
ARG   HD2  H N N 89  
ARG   HD3  H N N 90  
ARG   HE   H N N 91  
ARG   HH11 H N N 92  
ARG   HH12 H N N 93  
ARG   HH21 H N N 94  
ARG   HH22 H N N 95  
ARG   HXT  H N N 96  
ASN   N    N N N 97  
ASN   CA   C N S 98  
ASN   C    C N N 99  
ASN   O    O N N 100 
ASN   CB   C N N 101 
ASN   CG   C N N 102 
ASN   OD1  O N N 103 
ASN   ND2  N N N 104 
ASN   OXT  O N N 105 
ASN   H    H N N 106 
ASN   H2   H N N 107 
ASN   HA   H N N 108 
ASN   HB2  H N N 109 
ASN   HB3  H N N 110 
ASN   HD21 H N N 111 
ASN   HD22 H N N 112 
ASN   HXT  H N N 113 
ASP   N    N N N 114 
ASP   CA   C N S 115 
ASP   C    C N N 116 
ASP   O    O N N 117 
ASP   CB   C N N 118 
ASP   CG   C N N 119 
ASP   OD1  O N N 120 
ASP   OD2  O N N 121 
ASP   OXT  O N N 122 
ASP   H    H N N 123 
ASP   H2   H N N 124 
ASP   HA   H N N 125 
ASP   HB2  H N N 126 
ASP   HB3  H N N 127 
ASP   HD2  H N N 128 
ASP   HXT  H N N 129 
CYS   N    N N N 130 
CYS   CA   C N R 131 
CYS   C    C N N 132 
CYS   O    O N N 133 
CYS   CB   C N N 134 
CYS   SG   S N N 135 
CYS   OXT  O N N 136 
CYS   H    H N N 137 
CYS   H2   H N N 138 
CYS   HA   H N N 139 
CYS   HB2  H N N 140 
CYS   HB3  H N N 141 
CYS   HG   H N N 142 
CYS   HXT  H N N 143 
GLN   N    N N N 144 
GLN   CA   C N S 145 
GLN   C    C N N 146 
GLN   O    O N N 147 
GLN   CB   C N N 148 
GLN   CG   C N N 149 
GLN   CD   C N N 150 
GLN   OE1  O N N 151 
GLN   NE2  N N N 152 
GLN   OXT  O N N 153 
GLN   H    H N N 154 
GLN   H2   H N N 155 
GLN   HA   H N N 156 
GLN   HB2  H N N 157 
GLN   HB3  H N N 158 
GLN   HG2  H N N 159 
GLN   HG3  H N N 160 
GLN   HE21 H N N 161 
GLN   HE22 H N N 162 
GLN   HXT  H N N 163 
GLU   N    N N N 164 
GLU   CA   C N S 165 
GLU   C    C N N 166 
GLU   O    O N N 167 
GLU   CB   C N N 168 
GLU   CG   C N N 169 
GLU   CD   C N N 170 
GLU   OE1  O N N 171 
GLU   OE2  O N N 172 
GLU   OXT  O N N 173 
GLU   H    H N N 174 
GLU   H2   H N N 175 
GLU   HA   H N N 176 
GLU   HB2  H N N 177 
GLU   HB3  H N N 178 
GLU   HG2  H N N 179 
GLU   HG3  H N N 180 
GLU   HE2  H N N 181 
GLU   HXT  H N N 182 
GLY   N    N N N 183 
GLY   CA   C N N 184 
GLY   C    C N N 185 
GLY   O    O N N 186 
GLY   OXT  O N N 187 
GLY   H    H N N 188 
GLY   H2   H N N 189 
GLY   HA2  H N N 190 
GLY   HA3  H N N 191 
GLY   HXT  H N N 192 
HIS   N    N N N 193 
HIS   CA   C N S 194 
HIS   C    C N N 195 
HIS   O    O N N 196 
HIS   CB   C N N 197 
HIS   CG   C Y N 198 
HIS   ND1  N Y N 199 
HIS   CD2  C Y N 200 
HIS   CE1  C Y N 201 
HIS   NE2  N Y N 202 
HIS   OXT  O N N 203 
HIS   H    H N N 204 
HIS   H2   H N N 205 
HIS   HA   H N N 206 
HIS   HB2  H N N 207 
HIS   HB3  H N N 208 
HIS   HD1  H N N 209 
HIS   HD2  H N N 210 
HIS   HE1  H N N 211 
HIS   HE2  H N N 212 
HIS   HXT  H N N 213 
HOH   O    O N N 214 
HOH   H1   H N N 215 
HOH   H2   H N N 216 
ILE   N    N N N 217 
ILE   CA   C N S 218 
ILE   C    C N N 219 
ILE   O    O N N 220 
ILE   CB   C N S 221 
ILE   CG1  C N N 222 
ILE   CG2  C N N 223 
ILE   CD1  C N N 224 
ILE   OXT  O N N 225 
ILE   H    H N N 226 
ILE   H2   H N N 227 
ILE   HA   H N N 228 
ILE   HB   H N N 229 
ILE   HG12 H N N 230 
ILE   HG13 H N N 231 
ILE   HG21 H N N 232 
ILE   HG22 H N N 233 
ILE   HG23 H N N 234 
ILE   HD11 H N N 235 
ILE   HD12 H N N 236 
ILE   HD13 H N N 237 
ILE   HXT  H N N 238 
LEU   N    N N N 239 
LEU   CA   C N S 240 
LEU   C    C N N 241 
LEU   O    O N N 242 
LEU   CB   C N N 243 
LEU   CG   C N N 244 
LEU   CD1  C N N 245 
LEU   CD2  C N N 246 
LEU   OXT  O N N 247 
LEU   H    H N N 248 
LEU   H2   H N N 249 
LEU   HA   H N N 250 
LEU   HB2  H N N 251 
LEU   HB3  H N N 252 
LEU   HG   H N N 253 
LEU   HD11 H N N 254 
LEU   HD12 H N N 255 
LEU   HD13 H N N 256 
LEU   HD21 H N N 257 
LEU   HD22 H N N 258 
LEU   HD23 H N N 259 
LEU   HXT  H N N 260 
LYS   N    N N N 261 
LYS   CA   C N S 262 
LYS   C    C N N 263 
LYS   O    O N N 264 
LYS   CB   C N N 265 
LYS   CG   C N N 266 
LYS   CD   C N N 267 
LYS   CE   C N N 268 
LYS   NZ   N N N 269 
LYS   OXT  O N N 270 
LYS   H    H N N 271 
LYS   H2   H N N 272 
LYS   HA   H N N 273 
LYS   HB2  H N N 274 
LYS   HB3  H N N 275 
LYS   HG2  H N N 276 
LYS   HG3  H N N 277 
LYS   HD2  H N N 278 
LYS   HD3  H N N 279 
LYS   HE2  H N N 280 
LYS   HE3  H N N 281 
LYS   HZ1  H N N 282 
LYS   HZ2  H N N 283 
LYS   HZ3  H N N 284 
LYS   HXT  H N N 285 
MET   N    N N N 286 
MET   CA   C N S 287 
MET   C    C N N 288 
MET   O    O N N 289 
MET   CB   C N N 290 
MET   CG   C N N 291 
MET   SD   S N N 292 
MET   CE   C N N 293 
MET   OXT  O N N 294 
MET   H    H N N 295 
MET   H2   H N N 296 
MET   HA   H N N 297 
MET   HB2  H N N 298 
MET   HB3  H N N 299 
MET   HG2  H N N 300 
MET   HG3  H N N 301 
MET   HE1  H N N 302 
MET   HE2  H N N 303 
MET   HE3  H N N 304 
MET   HXT  H N N 305 
PHE   N    N N N 306 
PHE   CA   C N S 307 
PHE   C    C N N 308 
PHE   O    O N N 309 
PHE   CB   C N N 310 
PHE   CG   C Y N 311 
PHE   CD1  C Y N 312 
PHE   CD2  C Y N 313 
PHE   CE1  C Y N 314 
PHE   CE2  C Y N 315 
PHE   CZ   C Y N 316 
PHE   OXT  O N N 317 
PHE   H    H N N 318 
PHE   H2   H N N 319 
PHE   HA   H N N 320 
PHE   HB2  H N N 321 
PHE   HB3  H N N 322 
PHE   HD1  H N N 323 
PHE   HD2  H N N 324 
PHE   HE1  H N N 325 
PHE   HE2  H N N 326 
PHE   HZ   H N N 327 
PHE   HXT  H N N 328 
PRO   N    N N N 329 
PRO   CA   C N S 330 
PRO   C    C N N 331 
PRO   O    O N N 332 
PRO   CB   C N N 333 
PRO   CG   C N N 334 
PRO   CD   C N N 335 
PRO   OXT  O N N 336 
PRO   H    H N N 337 
PRO   HA   H N N 338 
PRO   HB2  H N N 339 
PRO   HB3  H N N 340 
PRO   HG2  H N N 341 
PRO   HG3  H N N 342 
PRO   HD2  H N N 343 
PRO   HD3  H N N 344 
PRO   HXT  H N N 345 
SER   N    N N N 346 
SER   CA   C N S 347 
SER   C    C N N 348 
SER   O    O N N 349 
SER   CB   C N N 350 
SER   OG   O N N 351 
SER   OXT  O N N 352 
SER   H    H N N 353 
SER   H2   H N N 354 
SER   HA   H N N 355 
SER   HB2  H N N 356 
SER   HB3  H N N 357 
SER   HG   H N N 358 
SER   HXT  H N N 359 
THR   N    N N N 360 
THR   CA   C N S 361 
THR   C    C N N 362 
THR   O    O N N 363 
THR   CB   C N R 364 
THR   OG1  O N N 365 
THR   CG2  C N N 366 
THR   OXT  O N N 367 
THR   H    H N N 368 
THR   H2   H N N 369 
THR   HA   H N N 370 
THR   HB   H N N 371 
THR   HG1  H N N 372 
THR   HG21 H N N 373 
THR   HG22 H N N 374 
THR   HG23 H N N 375 
THR   HXT  H N N 376 
TRP   N    N N N 377 
TRP   CA   C N S 378 
TRP   C    C N N 379 
TRP   O    O N N 380 
TRP   CB   C N N 381 
TRP   CG   C Y N 382 
TRP   CD1  C Y N 383 
TRP   CD2  C Y N 384 
TRP   NE1  N Y N 385 
TRP   CE2  C Y N 386 
TRP   CE3  C Y N 387 
TRP   CZ2  C Y N 388 
TRP   CZ3  C Y N 389 
TRP   CH2  C Y N 390 
TRP   OXT  O N N 391 
TRP   H    H N N 392 
TRP   H2   H N N 393 
TRP   HA   H N N 394 
TRP   HB2  H N N 395 
TRP   HB3  H N N 396 
TRP   HD1  H N N 397 
TRP   HE1  H N N 398 
TRP   HE3  H N N 399 
TRP   HZ2  H N N 400 
TRP   HZ3  H N N 401 
TRP   HH2  H N N 402 
TRP   HXT  H N N 403 
TYR   N    N N N 404 
TYR   CA   C N S 405 
TYR   C    C N N 406 
TYR   O    O N N 407 
TYR   CB   C N N 408 
TYR   CG   C Y N 409 
TYR   CD1  C Y N 410 
TYR   CD2  C Y N 411 
TYR   CE1  C Y N 412 
TYR   CE2  C Y N 413 
TYR   CZ   C Y N 414 
TYR   OH   O N N 415 
TYR   OXT  O N N 416 
TYR   H    H N N 417 
TYR   H2   H N N 418 
TYR   HA   H N N 419 
TYR   HB2  H N N 420 
TYR   HB3  H N N 421 
TYR   HD1  H N N 422 
TYR   HD2  H N N 423 
TYR   HE1  H N N 424 
TYR   HE2  H N N 425 
TYR   HH   H N N 426 
TYR   HXT  H N N 427 
VAL   N    N N N 428 
VAL   CA   C N S 429 
VAL   C    C N N 430 
VAL   O    O N N 431 
VAL   CB   C N N 432 
VAL   CG1  C N N 433 
VAL   CG2  C N N 434 
VAL   OXT  O N N 435 
VAL   H    H N N 436 
VAL   H2   H N N 437 
VAL   HA   H N N 438 
VAL   HB   H N N 439 
VAL   HG11 H N N 440 
VAL   HG12 H N N 441 
VAL   HG13 H N N 442 
VAL   HG21 H N N 443 
VAL   HG22 H N N 444 
VAL   HG23 H N N 445 
VAL   HXT  H N N 446 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1IRC C01 C02  doub Y N 1   
A1IRC C02 C03  sing Y N 2   
A1IRC C03 C04  doub Y N 3   
A1IRC C04 C05  sing Y N 4   
A1IRC C05 C06  doub Y N 5   
A1IRC C06 C01  sing Y N 6   
A1IRC C02 C07  sing N N 7   
A1IRC C07 C08  trip N N 8   
A1IRC C08 C09  sing N N 9   
A1IRC C09 C10  doub Y N 10  
A1IRC C10 N11  sing Y N 11  
A1IRC N11 C12  doub Y N 12  
A1IRC C12 N13  sing Y N 13  
A1IRC N13 C09  sing Y N 14  
A1IRC C12 C14  sing Y N 15  
A1IRC C14 C15  doub Y N 16  
A1IRC C15 C16  sing Y N 17  
A1IRC C16 N17  doub Y N 18  
A1IRC N17 N13  sing Y N 19  
A1IRC C04 C18  sing N N 20  
A1IRC C18 N19  sing N N 21  
A1IRC N19 C20  sing N N 22  
A1IRC C20 C21  doub Y N 23  
A1IRC C21 C22  sing Y N 24  
A1IRC C22 C23  doub Y N 25  
A1IRC C23 C24  sing Y N 26  
A1IRC C24 C25  doub Y N 27  
A1IRC C25 C20  sing Y N 28  
A1IRC C23 N26  sing N N 29  
A1IRC N26 C27  sing N N 30  
A1IRC C27 C28  sing N N 31  
A1IRC C28 C29  sing N N 32  
A1IRC C27 O30  doub N N 33  
A1IRC C22 C31  sing N N 34  
A1IRC C31 F32  sing N N 35  
A1IRC C31 F33  sing N N 36  
A1IRC C31 F34  sing N N 37  
A1IRC C01 C35  sing N N 38  
A1IRC C18 O36  doub N N 39  
A1IRC C10 H101 sing N N 40  
A1IRC C15 H151 sing N N 41  
A1IRC C21 H211 sing N N 42  
A1IRC C24 H241 sing N N 43  
A1IRC C28 H282 sing N N 44  
A1IRC C28 H281 sing N N 45  
A1IRC C03 H031 sing N N 46  
A1IRC C05 H051 sing N N 47  
A1IRC C06 H061 sing N N 48  
A1IRC C14 H141 sing N N 49  
A1IRC C16 H161 sing N N 50  
A1IRC C25 H251 sing N N 51  
A1IRC C29 H293 sing N N 52  
A1IRC C29 H292 sing N N 53  
A1IRC C29 H291 sing N N 54  
A1IRC C35 H353 sing N N 55  
A1IRC C35 H352 sing N N 56  
A1IRC C35 H351 sing N N 57  
A1IRC N19 H191 sing N N 58  
A1IRC N26 H261 sing N N 59  
ALA   N   CA   sing N N 60  
ALA   N   H    sing N N 61  
ALA   N   H2   sing N N 62  
ALA   CA  C    sing N N 63  
ALA   CA  CB   sing N N 64  
ALA   CA  HA   sing N N 65  
ALA   C   O    doub N N 66  
ALA   C   OXT  sing N N 67  
ALA   CB  HB1  sing N N 68  
ALA   CB  HB2  sing N N 69  
ALA   CB  HB3  sing N N 70  
ALA   OXT HXT  sing N N 71  
ARG   N   CA   sing N N 72  
ARG   N   H    sing N N 73  
ARG   N   H2   sing N N 74  
ARG   CA  C    sing N N 75  
ARG   CA  CB   sing N N 76  
ARG   CA  HA   sing N N 77  
ARG   C   O    doub N N 78  
ARG   C   OXT  sing N N 79  
ARG   CB  CG   sing N N 80  
ARG   CB  HB2  sing N N 81  
ARG   CB  HB3  sing N N 82  
ARG   CG  CD   sing N N 83  
ARG   CG  HG2  sing N N 84  
ARG   CG  HG3  sing N N 85  
ARG   CD  NE   sing N N 86  
ARG   CD  HD2  sing N N 87  
ARG   CD  HD3  sing N N 88  
ARG   NE  CZ   sing N N 89  
ARG   NE  HE   sing N N 90  
ARG   CZ  NH1  sing N N 91  
ARG   CZ  NH2  doub N N 92  
ARG   NH1 HH11 sing N N 93  
ARG   NH1 HH12 sing N N 94  
ARG   NH2 HH21 sing N N 95  
ARG   NH2 HH22 sing N N 96  
ARG   OXT HXT  sing N N 97  
ASN   N   CA   sing N N 98  
ASN   N   H    sing N N 99  
ASN   N   H2   sing N N 100 
ASN   CA  C    sing N N 101 
ASN   CA  CB   sing N N 102 
ASN   CA  HA   sing N N 103 
ASN   C   O    doub N N 104 
ASN   C   OXT  sing N N 105 
ASN   CB  CG   sing N N 106 
ASN   CB  HB2  sing N N 107 
ASN   CB  HB3  sing N N 108 
ASN   CG  OD1  doub N N 109 
ASN   CG  ND2  sing N N 110 
ASN   ND2 HD21 sing N N 111 
ASN   ND2 HD22 sing N N 112 
ASN   OXT HXT  sing N N 113 
ASP   N   CA   sing N N 114 
ASP   N   H    sing N N 115 
ASP   N   H2   sing N N 116 
ASP   CA  C    sing N N 117 
ASP   CA  CB   sing N N 118 
ASP   CA  HA   sing N N 119 
ASP   C   O    doub N N 120 
ASP   C   OXT  sing N N 121 
ASP   CB  CG   sing N N 122 
ASP   CB  HB2  sing N N 123 
ASP   CB  HB3  sing N N 124 
ASP   CG  OD1  doub N N 125 
ASP   CG  OD2  sing N N 126 
ASP   OD2 HD2  sing N N 127 
ASP   OXT HXT  sing N N 128 
CYS   N   CA   sing N N 129 
CYS   N   H    sing N N 130 
CYS   N   H2   sing N N 131 
CYS   CA  C    sing N N 132 
CYS   CA  CB   sing N N 133 
CYS   CA  HA   sing N N 134 
CYS   C   O    doub N N 135 
CYS   C   OXT  sing N N 136 
CYS   CB  SG   sing N N 137 
CYS   CB  HB2  sing N N 138 
CYS   CB  HB3  sing N N 139 
CYS   SG  HG   sing N N 140 
CYS   OXT HXT  sing N N 141 
GLN   N   CA   sing N N 142 
GLN   N   H    sing N N 143 
GLN   N   H2   sing N N 144 
GLN   CA  C    sing N N 145 
GLN   CA  CB   sing N N 146 
GLN   CA  HA   sing N N 147 
GLN   C   O    doub N N 148 
GLN   C   OXT  sing N N 149 
GLN   CB  CG   sing N N 150 
GLN   CB  HB2  sing N N 151 
GLN   CB  HB3  sing N N 152 
GLN   CG  CD   sing N N 153 
GLN   CG  HG2  sing N N 154 
GLN   CG  HG3  sing N N 155 
GLN   CD  OE1  doub N N 156 
GLN   CD  NE2  sing N N 157 
GLN   NE2 HE21 sing N N 158 
GLN   NE2 HE22 sing N N 159 
GLN   OXT HXT  sing N N 160 
GLU   N   CA   sing N N 161 
GLU   N   H    sing N N 162 
GLU   N   H2   sing N N 163 
GLU   CA  C    sing N N 164 
GLU   CA  CB   sing N N 165 
GLU   CA  HA   sing N N 166 
GLU   C   O    doub N N 167 
GLU   C   OXT  sing N N 168 
GLU   CB  CG   sing N N 169 
GLU   CB  HB2  sing N N 170 
GLU   CB  HB3  sing N N 171 
GLU   CG  CD   sing N N 172 
GLU   CG  HG2  sing N N 173 
GLU   CG  HG3  sing N N 174 
GLU   CD  OE1  doub N N 175 
GLU   CD  OE2  sing N N 176 
GLU   OE2 HE2  sing N N 177 
GLU   OXT HXT  sing N N 178 
GLY   N   CA   sing N N 179 
GLY   N   H    sing N N 180 
GLY   N   H2   sing N N 181 
GLY   CA  C    sing N N 182 
GLY   CA  HA2  sing N N 183 
GLY   CA  HA3  sing N N 184 
GLY   C   O    doub N N 185 
GLY   C   OXT  sing N N 186 
GLY   OXT HXT  sing N N 187 
HIS   N   CA   sing N N 188 
HIS   N   H    sing N N 189 
HIS   N   H2   sing N N 190 
HIS   CA  C    sing N N 191 
HIS   CA  CB   sing N N 192 
HIS   CA  HA   sing N N 193 
HIS   C   O    doub N N 194 
HIS   C   OXT  sing N N 195 
HIS   CB  CG   sing N N 196 
HIS   CB  HB2  sing N N 197 
HIS   CB  HB3  sing N N 198 
HIS   CG  ND1  sing Y N 199 
HIS   CG  CD2  doub Y N 200 
HIS   ND1 CE1  doub Y N 201 
HIS   ND1 HD1  sing N N 202 
HIS   CD2 NE2  sing Y N 203 
HIS   CD2 HD2  sing N N 204 
HIS   CE1 NE2  sing Y N 205 
HIS   CE1 HE1  sing N N 206 
HIS   NE2 HE2  sing N N 207 
HIS   OXT HXT  sing N N 208 
HOH   O   H1   sing N N 209 
HOH   O   H2   sing N N 210 
ILE   N   CA   sing N N 211 
ILE   N   H    sing N N 212 
ILE   N   H2   sing N N 213 
ILE   CA  C    sing N N 214 
ILE   CA  CB   sing N N 215 
ILE   CA  HA   sing N N 216 
ILE   C   O    doub N N 217 
ILE   C   OXT  sing N N 218 
ILE   CB  CG1  sing N N 219 
ILE   CB  CG2  sing N N 220 
ILE   CB  HB   sing N N 221 
ILE   CG1 CD1  sing N N 222 
ILE   CG1 HG12 sing N N 223 
ILE   CG1 HG13 sing N N 224 
ILE   CG2 HG21 sing N N 225 
ILE   CG2 HG22 sing N N 226 
ILE   CG2 HG23 sing N N 227 
ILE   CD1 HD11 sing N N 228 
ILE   CD1 HD12 sing N N 229 
ILE   CD1 HD13 sing N N 230 
ILE   OXT HXT  sing N N 231 
LEU   N   CA   sing N N 232 
LEU   N   H    sing N N 233 
LEU   N   H2   sing N N 234 
LEU   CA  C    sing N N 235 
LEU   CA  CB   sing N N 236 
LEU   CA  HA   sing N N 237 
LEU   C   O    doub N N 238 
LEU   C   OXT  sing N N 239 
LEU   CB  CG   sing N N 240 
LEU   CB  HB2  sing N N 241 
LEU   CB  HB3  sing N N 242 
LEU   CG  CD1  sing N N 243 
LEU   CG  CD2  sing N N 244 
LEU   CG  HG   sing N N 245 
LEU   CD1 HD11 sing N N 246 
LEU   CD1 HD12 sing N N 247 
LEU   CD1 HD13 sing N N 248 
LEU   CD2 HD21 sing N N 249 
LEU   CD2 HD22 sing N N 250 
LEU   CD2 HD23 sing N N 251 
LEU   OXT HXT  sing N N 252 
LYS   N   CA   sing N N 253 
LYS   N   H    sing N N 254 
LYS   N   H2   sing N N 255 
LYS   CA  C    sing N N 256 
LYS   CA  CB   sing N N 257 
LYS   CA  HA   sing N N 258 
LYS   C   O    doub N N 259 
LYS   C   OXT  sing N N 260 
LYS   CB  CG   sing N N 261 
LYS   CB  HB2  sing N N 262 
LYS   CB  HB3  sing N N 263 
LYS   CG  CD   sing N N 264 
LYS   CG  HG2  sing N N 265 
LYS   CG  HG3  sing N N 266 
LYS   CD  CE   sing N N 267 
LYS   CD  HD2  sing N N 268 
LYS   CD  HD3  sing N N 269 
LYS   CE  NZ   sing N N 270 
LYS   CE  HE2  sing N N 271 
LYS   CE  HE3  sing N N 272 
LYS   NZ  HZ1  sing N N 273 
LYS   NZ  HZ2  sing N N 274 
LYS   NZ  HZ3  sing N N 275 
LYS   OXT HXT  sing N N 276 
MET   N   CA   sing N N 277 
MET   N   H    sing N N 278 
MET   N   H2   sing N N 279 
MET   CA  C    sing N N 280 
MET   CA  CB   sing N N 281 
MET   CA  HA   sing N N 282 
MET   C   O    doub N N 283 
MET   C   OXT  sing N N 284 
MET   CB  CG   sing N N 285 
MET   CB  HB2  sing N N 286 
MET   CB  HB3  sing N N 287 
MET   CG  SD   sing N N 288 
MET   CG  HG2  sing N N 289 
MET   CG  HG3  sing N N 290 
MET   SD  CE   sing N N 291 
MET   CE  HE1  sing N N 292 
MET   CE  HE2  sing N N 293 
MET   CE  HE3  sing N N 294 
MET   OXT HXT  sing N N 295 
PHE   N   CA   sing N N 296 
PHE   N   H    sing N N 297 
PHE   N   H2   sing N N 298 
PHE   CA  C    sing N N 299 
PHE   CA  CB   sing N N 300 
PHE   CA  HA   sing N N 301 
PHE   C   O    doub N N 302 
PHE   C   OXT  sing N N 303 
PHE   CB  CG   sing N N 304 
PHE   CB  HB2  sing N N 305 
PHE   CB  HB3  sing N N 306 
PHE   CG  CD1  doub Y N 307 
PHE   CG  CD2  sing Y N 308 
PHE   CD1 CE1  sing Y N 309 
PHE   CD1 HD1  sing N N 310 
PHE   CD2 CE2  doub Y N 311 
PHE   CD2 HD2  sing N N 312 
PHE   CE1 CZ   doub Y N 313 
PHE   CE1 HE1  sing N N 314 
PHE   CE2 CZ   sing Y N 315 
PHE   CE2 HE2  sing N N 316 
PHE   CZ  HZ   sing N N 317 
PHE   OXT HXT  sing N N 318 
PRO   N   CA   sing N N 319 
PRO   N   CD   sing N N 320 
PRO   N   H    sing N N 321 
PRO   CA  C    sing N N 322 
PRO   CA  CB   sing N N 323 
PRO   CA  HA   sing N N 324 
PRO   C   O    doub N N 325 
PRO   C   OXT  sing N N 326 
PRO   CB  CG   sing N N 327 
PRO   CB  HB2  sing N N 328 
PRO   CB  HB3  sing N N 329 
PRO   CG  CD   sing N N 330 
PRO   CG  HG2  sing N N 331 
PRO   CG  HG3  sing N N 332 
PRO   CD  HD2  sing N N 333 
PRO   CD  HD3  sing N N 334 
PRO   OXT HXT  sing N N 335 
SER   N   CA   sing N N 336 
SER   N   H    sing N N 337 
SER   N   H2   sing N N 338 
SER   CA  C    sing N N 339 
SER   CA  CB   sing N N 340 
SER   CA  HA   sing N N 341 
SER   C   O    doub N N 342 
SER   C   OXT  sing N N 343 
SER   CB  OG   sing N N 344 
SER   CB  HB2  sing N N 345 
SER   CB  HB3  sing N N 346 
SER   OG  HG   sing N N 347 
SER   OXT HXT  sing N N 348 
THR   N   CA   sing N N 349 
THR   N   H    sing N N 350 
THR   N   H2   sing N N 351 
THR   CA  C    sing N N 352 
THR   CA  CB   sing N N 353 
THR   CA  HA   sing N N 354 
THR   C   O    doub N N 355 
THR   C   OXT  sing N N 356 
THR   CB  OG1  sing N N 357 
THR   CB  CG2  sing N N 358 
THR   CB  HB   sing N N 359 
THR   OG1 HG1  sing N N 360 
THR   CG2 HG21 sing N N 361 
THR   CG2 HG22 sing N N 362 
THR   CG2 HG23 sing N N 363 
THR   OXT HXT  sing N N 364 
TRP   N   CA   sing N N 365 
TRP   N   H    sing N N 366 
TRP   N   H2   sing N N 367 
TRP   CA  C    sing N N 368 
TRP   CA  CB   sing N N 369 
TRP   CA  HA   sing N N 370 
TRP   C   O    doub N N 371 
TRP   C   OXT  sing N N 372 
TRP   CB  CG   sing N N 373 
TRP   CB  HB2  sing N N 374 
TRP   CB  HB3  sing N N 375 
TRP   CG  CD1  doub Y N 376 
TRP   CG  CD2  sing Y N 377 
TRP   CD1 NE1  sing Y N 378 
TRP   CD1 HD1  sing N N 379 
TRP   CD2 CE2  doub Y N 380 
TRP   CD2 CE3  sing Y N 381 
TRP   NE1 CE2  sing Y N 382 
TRP   NE1 HE1  sing N N 383 
TRP   CE2 CZ2  sing Y N 384 
TRP   CE3 CZ3  doub Y N 385 
TRP   CE3 HE3  sing N N 386 
TRP   CZ2 CH2  doub Y N 387 
TRP   CZ2 HZ2  sing N N 388 
TRP   CZ3 CH2  sing Y N 389 
TRP   CZ3 HZ3  sing N N 390 
TRP   CH2 HH2  sing N N 391 
TRP   OXT HXT  sing N N 392 
TYR   N   CA   sing N N 393 
TYR   N   H    sing N N 394 
TYR   N   H2   sing N N 395 
TYR   CA  C    sing N N 396 
TYR   CA  CB   sing N N 397 
TYR   CA  HA   sing N N 398 
TYR   C   O    doub N N 399 
TYR   C   OXT  sing N N 400 
TYR   CB  CG   sing N N 401 
TYR   CB  HB2  sing N N 402 
TYR   CB  HB3  sing N N 403 
TYR   CG  CD1  doub Y N 404 
TYR   CG  CD2  sing Y N 405 
TYR   CD1 CE1  sing Y N 406 
TYR   CD1 HD1  sing N N 407 
TYR   CD2 CE2  doub Y N 408 
TYR   CD2 HD2  sing N N 409 
TYR   CE1 CZ   doub Y N 410 
TYR   CE1 HE1  sing N N 411 
TYR   CE2 CZ   sing Y N 412 
TYR   CE2 HE2  sing N N 413 
TYR   CZ  OH   sing N N 414 
TYR   OH  HH   sing N N 415 
TYR   OXT HXT  sing N N 416 
VAL   N   CA   sing N N 417 
VAL   N   H    sing N N 418 
VAL   N   H2   sing N N 419 
VAL   CA  C    sing N N 420 
VAL   CA  CB   sing N N 421 
VAL   CA  HA   sing N N 422 
VAL   C   O    doub N N 423 
VAL   C   OXT  sing N N 424 
VAL   CB  CG1  sing N N 425 
VAL   CB  CG2  sing N N 426 
VAL   CB  HB   sing N N 427 
VAL   CG1 HG11 sing N N 428 
VAL   CG1 HG12 sing N N 429 
VAL   CG1 HG13 sing N N 430 
VAL   CG2 HG21 sing N N 431 
VAL   CG2 HG22 sing N N 432 
VAL   CG2 HG23 sing N N 433 
VAL   OXT HXT  sing N N 434 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'German Research Foundation (DFG)'                   Germany          'RA 1055/3-2' 1 
'European Regional Development Fund'                 'European Union' EFRE-800400   2 
'German Federal Ministry for Education and Research' Germany          01ZX2201B     3 
'Other government'                                   Germany          NW21-062C     4 
'Other private'                                      ?                Ex-2021-0033  5 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5GRN 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 6' 
_space_group.name_Hall        'P 6' 
_space_group.IT_number        168 
_space_group.crystal_system   hexagonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9GZH 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.007357 
_atom_sites.fract_transf_matrix[1][2]   0.004248 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.008495 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.028827 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
F ? ? 4.90428 4.07044 ? ? 12.99538 1.63651  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ASP   A 1 37  ? -46.29230 4.63464   -8.16364  1.000 98.77164  ? 583  ASP   A N   1 
ATOM   2    C CA  . ASP   A 1 37  ? -47.42688 5.40568   -8.65639  1.000 98.65365  ? 583  ASP   A CA  1 
ATOM   3    C C   . ASP   A 1 37  ? -47.64636 6.64185   -7.79167  1.000 90.75182  ? 583  ASP   A C   1 
ATOM   4    O O   . ASP   A 1 37  ? -47.61437 6.56610   -6.56314  1.000 95.64103  ? 583  ASP   A O   1 
ATOM   5    C CB  . ASP   A 1 37  ? -48.68965 4.54118   -8.68086  1.000 105.49954 ? 583  ASP   A CB  1 
ATOM   6    C CG  . ASP   A 1 37  ? -49.84541 5.20025   -9.42178  1.000 110.50754 ? 583  ASP   A CG  1 
ATOM   7    O OD1 . ASP   A 1 37  ? -49.93737 6.44667   -9.43868  1.000 112.41931 ? 583  ASP   A OD1 1 
ATOM   8    O OD2 . ASP   A 1 37  ? -50.67460 4.45992   -9.99130  1.000 112.60153 ? 583  ASP   A OD2 1 
ATOM   9    N N   . SER   A 1 38  ? -47.88047 7.78061   -8.44498  1.000 151.31248 ? 584  SER   A N   1 
ATOM   10   C CA  . SER   A 1 38  ? -48.10910 9.03574   -7.74095  1.000 127.46021 ? 584  SER   A CA  1 
ATOM   11   C C   . SER   A 1 38  ? -49.55370 9.21732   -7.29738  1.000 110.64350 ? 584  SER   A C   1 
ATOM   12   O O   . SER   A 1 38  ? -49.82828 10.12172  -6.50092  1.000 104.32202 ? 584  SER   A O   1 
ATOM   13   C CB  . SER   A 1 38  ? -47.69797 10.21671  -8.62249  1.000 126.20154 ? 584  SER   A CB  1 
ATOM   14   O OG  . SER   A 1 38  ? -48.40957 10.20590  -9.84645  1.000 126.82924 ? 584  SER   A OG  1 
ATOM   15   N N   . ARG   A 1 39  ? -50.47947 8.39257   -7.79461  1.000 105.16415 ? 585  ARG   A N   1 
ATOM   16   C CA  . ARG   A 1 39  ? -51.87256 8.50464   -7.37357  1.000 95.71946  ? 585  ARG   A CA  1 
ATOM   17   C C   . ARG   A 1 39  ? -52.02245 8.26557   -5.87920  1.000 87.83096  ? 585  ARG   A C   1 
ATOM   18   O O   . ARG   A 1 39  ? -52.90732 8.84626   -5.24199  1.000 85.04229  ? 585  ARG   A O   1 
ATOM   19   C CB  . ARG   A 1 39  ? -52.74064 7.51766   -8.15442  1.000 94.32094  ? 585  ARG   A CB  1 
ATOM   20   N N   . TRP   A 1 40  ? -51.16085 7.42863   -5.30249  1.000 85.01218  ? 586  TRP   A N   1 
ATOM   21   C CA  . TRP   A 1 40  ? -51.26937 7.07310   -3.89450  1.000 79.46279  ? 586  TRP   A CA  1 
ATOM   22   C C   . TRP   A 1 40  ? -50.74753 8.15344   -2.96086  1.000 75.27996  ? 586  TRP   A C   1 
ATOM   23   O O   . TRP   A 1 40  ? -51.13579 8.17433   -1.78694  1.000 66.77838  ? 586  TRP   A O   1 
ATOM   24   C CB  . TRP   A 1 40  ? -50.51258 5.77359   -3.62780  1.000 81.02716  ? 586  TRP   A CB  1 
ATOM   25   C CG  . TRP   A 1 40  ? -51.11287 4.60020   -4.31156  1.000 84.62130  ? 586  TRP   A CG  1 
ATOM   26   C CD1 . TRP   A 1 40  ? -50.60438 3.91873   -5.37763  1.000 89.27645  ? 586  TRP   A CD1 1 
ATOM   27   C CD2 . TRP   A 1 40  ? -52.35573 3.97267   -3.98741  1.000 83.55246  ? 586  TRP   A CD2 1 
ATOM   28   N NE1 . TRP   A 1 40  ? -51.45144 2.89595   -5.73167  1.000 91.42534  ? 586  TRP   A NE1 1 
ATOM   29   C CE2 . TRP   A 1 40  ? -52.53469 2.90844   -4.89222  1.000 88.17280  ? 586  TRP   A CE2 1 
ATOM   30   C CE3 . TRP   A 1 40  ? -53.33409 4.20466   -3.01441  1.000 80.75562  ? 586  TRP   A CE3 1 
ATOM   31   C CZ2 . TRP   A 1 40  ? -53.65260 2.07684   -4.85309  1.000 86.32947  ? 586  TRP   A CZ2 1 
ATOM   32   C CZ3 . TRP   A 1 40  ? -54.44100 3.38007   -2.97663  1.000 81.29958  ? 586  TRP   A CZ3 1 
ATOM   33   C CH2 . TRP   A 1 40  ? -54.59201 2.32862   -3.88968  1.000 82.66918  ? 586  TRP   A CH2 1 
ATOM   34   N N   . GLU   A 1 41  ? -49.88325 9.04002   -3.45041  1.000 78.13773  ? 587  GLU   A N   1 
ATOM   35   C CA  . GLU   A 1 41  ? -49.19668 9.97661   -2.57268  1.000 74.52715  ? 587  GLU   A CA  1 
ATOM   36   C C   . GLU   A 1 41  ? -50.19311 10.86682  -1.83957  1.000 69.55328  ? 587  GLU   A C   1 
ATOM   37   O O   . GLU   A 1 41  ? -51.22090 11.27090  -2.38941  1.000 71.94104  ? 587  GLU   A O   1 
ATOM   38   C CB  . GLU   A 1 41  ? -48.20688 10.82388  -3.37158  1.000 80.90799  ? 587  GLU   A CB  1 
ATOM   39   C CG  . GLU   A 1 41  ? -47.12125 11.46772  -2.52065  1.000 83.45014  ? 587  GLU   A CG  1 
ATOM   40   C CD  . GLU   A 1 41  ? -46.14935 10.45306  -1.94054  1.000 83.82689  ? 587  GLU   A CD  1 
ATOM   41   O OE1 . GLU   A 1 41  ? -46.10897 9.30569   -2.43591  1.000 86.08825  ? 587  GLU   A OE1 1 
ATOM   42   O OE2 . GLU   A 1 41  ? -45.41816 10.80620  -0.99173  1.000 82.73291  ? 587  GLU   A OE2 1 
ATOM   43   N N   . PHE   A 1 42  ? -49.88458 11.14780  -0.57531  1.000 63.99038  ? 588  PHE   A N   1 
ATOM   44   C CA  . PHE   A 1 42  ? -50.70625 11.91689  0.33941   1.000 59.53628  ? 588  PHE   A CA  1 
ATOM   45   C C   . PHE   A 1 42  ? -49.76958 12.83057  1.11530   1.000 65.42445  ? 588  PHE   A C   1 
ATOM   46   O O   . PHE   A 1 42  ? -48.69730 12.38734  1.55006   1.000 65.26362  ? 588  PHE   A O   1 
ATOM   47   C CB  . PHE   A 1 42  ? -51.48197 10.99844  1.29767   1.000 57.90687  ? 588  PHE   A CB  1 
ATOM   48   C CG  . PHE   A 1 42  ? -52.44127 11.71808  2.20628   1.000 58.46834  ? 588  PHE   A CG  1 
ATOM   49   C CD1 . PHE   A 1 42  ? -53.60470 12.28248  1.70645   1.000 61.23072  ? 588  PHE   A CD1 1 
ATOM   50   C CD2 . PHE   A 1 42  ? -52.19419 11.80033  3.56811   1.000 57.61536  ? 588  PHE   A CD2 1 
ATOM   51   C CE1 . PHE   A 1 42  ? -54.49456 12.93297  2.54363   1.000 59.18247  ? 588  PHE   A CE1 1 
ATOM   52   C CE2 . PHE   A 1 42  ? -53.08188 12.45142  4.41360   1.000 55.71178  ? 588  PHE   A CE2 1 
ATOM   53   C CZ  . PHE   A 1 42  ? -54.23266 13.01802  3.89845   1.000 55.99091  ? 588  PHE   A CZ  1 
ATOM   54   N N   . PRO   A 1 43  ? -50.12363 14.10269  1.28470   1.000 67.48879  ? 589  PRO   A N   1 
ATOM   55   C CA  . PRO   A 1 43  ? -49.20954 15.02465  1.96864   1.000 66.49848  ? 589  PRO   A CA  1 
ATOM   56   C C   . PRO   A 1 43  ? -49.14146 14.73896  3.45998   1.000 59.29117  ? 589  PRO   A C   1 
ATOM   57   O O   . PRO   A 1 43  ? -50.13438 14.36605  4.08955   1.000 58.28444  ? 589  PRO   A O   1 
ATOM   58   C CB  . PRO   A 1 43  ? -49.81688 16.40334  1.68755   1.000 69.78413  ? 589  PRO   A CB  1 
ATOM   59   C CG  . PRO   A 1 43  ? -51.26395 16.12818  1.45861   1.000 69.11324  ? 589  PRO   A CG  1 
ATOM   60   C CD  . PRO   A 1 43  ? -51.33238 14.78565  0.78886   1.000 68.74818  ? 589  PRO   A CD  1 
ATOM   61   N N   . ARG   A 1 44  ? -47.94740 14.92269  4.02370   1.000 63.88056  ? 590  ARG   A N   1 
ATOM   62   C CA  . ARG   A 1 44  ? -47.74848 14.61865  5.43426   1.000 62.31920  ? 590  ARG   A CA  1 
ATOM   63   C C   . ARG   A 1 44  ? -48.54055 15.56327  6.32464   1.000 62.23754  ? 590  ARG   A C   1 
ATOM   64   O O   . ARG   A 1 44  ? -49.04791 15.15089  7.37391   1.000 61.15444  ? 590  ARG   A O   1 
ATOM   65   C CB  . ARG   A 1 44  ? -46.26344 14.67635  5.77020   1.000 68.15221  ? 590  ARG   A CB  1 
ATOM   66   C CG  . ARG   A 1 44  ? -45.42571 13.78218  4.90172   1.000 75.72563  ? 590  ARG   A CG  1 
ATOM   67   C CD  . ARG   A 1 44  ? -43.97366 13.86911  5.28769   1.000 83.69435  ? 590  ARG   A CD  1 
ATOM   68   N NE  . ARG   A 1 44  ? -43.41190 12.54590  5.50421   1.000 88.72989  ? 590  ARG   A NE  1 
ATOM   69   C CZ  . ARG   A 1 44  ? -43.05217 11.72868  4.52392   1.000 88.52321  ? 590  ARG   A CZ  1 
ATOM   70   N NH1 . ARG   A 1 44  ? -43.19464 12.09547  3.25749   1.000 91.43287  ? 590  ARG   A NH1 1 
ATOM   71   N NH2 . ARG   A 1 44  ? -42.55473 10.54346  4.81076   1.000 83.30325  ? 590  ARG   A NH2 1 
ATOM   72   N N   . ASP   A 1 45  ? -48.66888 16.83233  5.92361   1.000 62.11553  ? 591  ASP   A N   1 
ATOM   73   C CA  . ASP   A 1 45  ? -49.37933 17.78526  6.76966   1.000 63.19753  ? 591  ASP   A CA  1 
ATOM   74   C C   . ASP   A 1 45  ? -50.87031 17.48329  6.86846   1.000 61.35036  ? 591  ASP   A C   1 
ATOM   75   O O   . ASP   A 1 45  ? -51.56364 18.12155  7.66738   1.000 64.66361  ? 591  ASP   A O   1 
ATOM   76   C CB  . ASP   A 1 45  ? -49.14769 19.22583  6.28666   1.000 69.70656  ? 591  ASP   A CB  1 
ATOM   77   C CG  . ASP   A 1 45  ? -49.67178 19.48978  4.88340   1.000 72.30947  ? 591  ASP   A CG  1 
ATOM   78   O OD1 . ASP   A 1 45  ? -50.40704 18.65398  4.32067   1.000 71.70642  ? 591  ASP   A OD1 1 
ATOM   79   O OD2 . ASP   A 1 45  ? -49.33034 20.56204  4.34034   1.000 79.41030  ? 591  ASP   A OD2 1 
ATOM   80   N N   . GLY   A 1 46  ? -51.37616 16.53650  6.08632   1.000 57.82833  ? 592  GLY   A N   1 
ATOM   81   C CA  . GLY   A 1 46  ? -52.74102 16.07949  6.20438   1.000 55.48627  ? 592  GLY   A CA  1 
ATOM   82   C C   . GLY   A 1 46  ? -52.92551 14.84385  7.06149   1.000 58.36004  ? 592  GLY   A C   1 
ATOM   83   O O   . GLY   A 1 46  ? -54.04465 14.32252  7.13743   1.000 54.99592  ? 592  GLY   A O   1 
ATOM   84   N N   . LEU   A 1 47  ? -51.86765 14.36461  7.72120   1.000 60.04002  ? 593  LEU   A N   1 
ATOM   85   C CA  . LEU   A 1 47  ? -51.89780 13.11711  8.47948   1.000 57.41244  ? 593  LEU   A CA  1 
ATOM   86   C C   . LEU   A 1 47  ? -51.52010 13.38689  9.93105   1.000 59.16096  ? 593  LEU   A C   1 
ATOM   87   O O   . LEU   A 1 47  ? -50.39627 13.81607  10.21693  1.000 59.83201  ? 593  LEU   A O   1 
ATOM   88   C CB  . LEU   A 1 47  ? -50.95405 12.08052  7.86091   1.000 56.39250  ? 593  LEU   A CB  1 
ATOM   89   C CG  . LEU   A 1 47  ? -51.05907 10.62647  8.31957   1.000 56.78824  ? 593  LEU   A CG  1 
ATOM   90   C CD1 . LEU   A 1 47  ? -52.40148 10.03307  7.92327   1.000 52.38115  ? 593  LEU   A CD1 1 
ATOM   91   C CD2 . LEU   A 1 47  ? -49.91890 9.79766   7.74632   1.000 59.39810  ? 593  LEU   A CD2 1 
ATOM   92   N N   . VAL   A 1 48  ? -52.45374 13.11486  10.84282  1.000 58.74640  ? 594  VAL   A N   1 
ATOM   93   C CA  . VAL   A 1 48  ? -52.22211 13.19617  12.28368  1.000 64.49450  ? 594  VAL   A CA  1 
ATOM   94   C C   . VAL   A 1 48  ? -51.88526 11.80228  12.79606  1.000 64.27853  ? 594  VAL   A C   1 
ATOM   95   O O   . VAL   A 1 48  ? -52.56629 10.82960  12.45326  1.000 67.46523  ? 594  VAL   A O   1 
ATOM   96   C CB  . VAL   A 1 48  ? -53.44977 13.77118  13.01324  1.000 67.09805  ? 594  VAL   A CB  1 
ATOM   97   C CG1 . VAL   A 1 48  ? -53.41895 13.41826  14.49660  1.000 70.31058  ? 594  VAL   A CG1 1 
ATOM   98   C CG2 . VAL   A 1 48  ? -53.52372 15.27853  12.81603  1.000 68.65877  ? 594  VAL   A CG2 1 
ATOM   99   N N   . LEU   A 1 49  ? -50.83148 11.69865  13.60445  1.000 65.08877  ? 595  LEU   A N   1 
ATOM   100  C CA  . LEU   A 1 49  ? -50.34608 10.42186  14.11603  1.000 66.82243  ? 595  LEU   A CA  1 
ATOM   101  C C   . LEU   A 1 49  ? -50.69903 10.28939  15.59084  1.000 65.71553  ? 595  LEU   A C   1 
ATOM   102  O O   . LEU   A 1 49  ? -50.45860 11.21296  16.37741  1.000 69.14820  ? 595  LEU   A O   1 
ATOM   103  C CB  . LEU   A 1 49  ? -48.83371 10.29090  13.92556  1.000 69.21990  ? 595  LEU   A CB  1 
ATOM   104  C CG  . LEU   A 1 49  ? -48.29281 10.37418  12.49545  1.000 71.03566  ? 595  LEU   A CG  1 
ATOM   105  C CD1 . LEU   A 1 49  ? -46.79043 10.14612  12.48241  1.000 77.65752  ? 595  LEU   A CD1 1 
ATOM   106  C CD2 . LEU   A 1 49  ? -48.99730 9.38518   11.56758  1.000 66.35853  ? 595  LEU   A CD2 1 
ATOM   107  N N   . GLY   A 1 50  ? -51.25429 9.13627   15.96128  1.000 60.37576  ? 596  GLY   A N   1 
ATOM   108  C CA  . GLY   A 1 50  ? -51.66986 8.89788   17.32975  1.000 61.71413  ? 596  GLY   A CA  1 
ATOM   109  C C   . GLY   A 1 50  ? -50.94652 7.74990   18.00470  1.000 64.40790  ? 596  GLY   A C   1 
ATOM   110  O O   . GLY   A 1 50  ? -49.76016 7.51602   17.75376  1.000 66.31869  ? 596  GLY   A O   1 
ATOM   111  N N   . ARG   A 1 51  ? -51.66340 7.01977   18.85586  1.000 62.87801  ? 597  ARG   A N   1 
ATOM   112  C CA  . ARG   A 1 51  ? -51.05287 5.99181   19.68810  1.000 68.21991  ? 597  ARG   A CA  1 
ATOM   113  C C   . ARG   A 1 51  ? -50.58410 4.80167   18.85524  1.000 69.21099  ? 597  ARG   A C   1 
ATOM   114  O O   . ARG   A 1 51  ? -51.11059 4.51762   17.77571  1.000 66.62813  ? 597  ARG   A O   1 
ATOM   115  C CB  . ARG   A 1 51  ? -52.04455 5.51279   20.74427  1.000 73.63233  ? 597  ARG   A CB  1 
ATOM   116  C CG  . ARG   A 1 51  ? -53.23897 4.79806   20.14076  1.000 78.19733  ? 597  ARG   A CG  1 
ATOM   117  C CD  . ARG   A 1 51  ? -54.27906 4.40873   21.17444  1.000 86.16544  ? 597  ARG   A CD  1 
ATOM   118  N NE  . ARG   A 1 51  ? -55.43844 3.80043   20.52947  1.000 89.94046  ? 597  ARG   A NE  1 
ATOM   119  C CZ  . ARG   A 1 51  ? -55.63130 2.49015   20.41240  1.000 95.64509  ? 597  ARG   A CZ  1 
ATOM   120  N NH1 . ARG   A 1 51  ? -54.74752 1.63717   20.91195  1.000 100.59576 ? 597  ARG   A NH1 1 
ATOM   121  N NH2 . ARG   A 1 51  ? -56.71316 2.03036   19.79904  1.000 94.46314  ? 597  ARG   A NH2 1 
ATOM   122  N N   . VAL   A 1 52  ? -49.58960 4.09036   19.38557  1.000 67.24221  ? 598  VAL   A N   1 
ATOM   123  C CA  . VAL   A 1 52  ? -49.04658 2.92534   18.70197  1.000 63.18632  ? 598  VAL   A CA  1 
ATOM   124  C C   . VAL   A 1 52  ? -49.99972 1.75033   18.85580  1.000 65.58210  ? 598  VAL   A C   1 
ATOM   125  O O   . VAL   A 1 52  ? -50.41437 1.40429   19.96964  1.000 67.43437  ? 598  VAL   A O   1 
ATOM   126  C CB  . VAL   A 1 52  ? -47.65705 2.57898   19.25234  1.000 66.33140  ? 598  VAL   A CB  1 
ATOM   127  C CG1 . VAL   A 1 52  ? -47.10436 1.34627   18.55399  1.000 65.07654  ? 598  VAL   A CG1 1 
ATOM   128  C CG2 . VAL   A 1 52  ? -46.71308 3.75904   19.09264  1.000 67.70933  ? 598  VAL   A CG2 1 
ATOM   129  N N   . LEU   A 1 53  ? -50.35232 1.12940   17.73304  1.000 64.64634  ? 599  LEU   A N   1 
ATOM   130  C CA  . LEU   A 1 53  ? -51.15724 -0.08559  17.75784  1.000 66.16919  ? 599  LEU   A CA  1 
ATOM   131  C C   . LEU   A 1 53  ? -50.30746 -1.34166  17.89002  1.000 67.68340  ? 599  LEU   A C   1 
ATOM   132  O O   . LEU   A 1 53  ? -50.75057 -2.32343  18.49818  1.000 69.93050  ? 599  LEU   A O   1 
ATOM   133  C CB  . LEU   A 1 53  ? -52.01265 -0.17575  16.49077  1.000 63.84986  ? 599  LEU   A CB  1 
ATOM   134  C CG  . LEU   A 1 53  ? -52.89339 1.04407   16.21718  1.000 61.28975  ? 599  LEU   A CG  1 
ATOM   135  C CD1 . LEU   A 1 53  ? -53.56255 0.93581   14.85896  1.000 59.59886  ? 599  LEU   A CD1 1 
ATOM   136  C CD2 . LEU   A 1 53  ? -53.92351 1.21879   17.32037  1.000 63.62316  ? 599  LEU   A CD2 1 
ATOM   137  N N   . GLY   A 1 54  ? -49.09818 -1.32736  17.33725  1.000 69.33786  ? 600  GLY   A N   1 
ATOM   138  C CA  . GLY   A 1 54  ? -48.17407 -2.43752  17.45437  1.000 71.70802  ? 600  GLY   A CA  1 
ATOM   139  C C   . GLY   A 1 54  ? -46.78656 -2.02111  17.01415  1.000 71.03698  ? 600  GLY   A C   1 
ATOM   140  O O   . GLY   A 1 54  ? -46.64913 -1.12999  16.17242  1.000 65.91746  ? 600  GLY   A O   1 
ATOM   141  N N   . SER   A 1 55  ? -45.75044 -2.64135  17.57176  1.000 71.90902  ? 601  SER   A N   1 
ATOM   142  C CA  . SER   A 1 55  ? -44.38798 -2.23699  17.26529  1.000 73.15348  ? 601  SER   A CA  1 
ATOM   143  C C   . SER   A 1 55  ? -43.45944 -3.43893  17.32162  1.000 75.66933  ? 601  SER   A C   1 
ATOM   144  O O   . SER   A 1 55  ? -43.59559 -4.30215  18.19381  1.000 75.43958  ? 601  SER   A O   1 
ATOM   145  C CB  . SER   A 1 55  ? -43.89772 -1.15612  18.23428  1.000 76.94835  ? 601  SER   A CB  1 
ATOM   146  O OG  . SER   A 1 55  ? -43.92661 -1.62464  19.57432  1.000 81.19607  ? 601  SER   A OG  1 
ATOM   147  N N   . GLY   A 1 56  ? -42.52415 -3.48945  16.37232  1.000 76.66010  ? 602  GLY   A N   1 
ATOM   148  C CA  . GLY   A 1 56  ? -41.42666 -4.42406  16.40426  1.000 82.86519  ? 602  GLY   A CA  1 
ATOM   149  C C   . GLY   A 1 56  ? -40.11560 -3.73845  16.74040  1.000 85.89464  ? 602  GLY   A C   1 
ATOM   150  O O   . GLY   A 1 56  ? -40.08138 -2.61604  17.24407  1.000 83.07931  ? 602  GLY   A O   1 
ATOM   151  N N   . ALA   A 1 57  ? -39.01889 -4.43662  16.43935  1.000 87.46718  ? 603  ALA   A N   1 
ATOM   152  C CA  . ALA   A 1 57  ? -37.70124 -3.87936  16.72223  1.000 90.81593  ? 603  ALA   A CA  1 
ATOM   153  C C   . ALA   A 1 57  ? -37.44609 -2.60418  15.92770  1.000 91.86677  ? 603  ALA   A C   1 
ATOM   154  O O   . ALA   A 1 57  ? -36.74081 -1.70769  16.40695  1.000 96.24615  ? 603  ALA   A O   1 
ATOM   155  C CB  . ALA   A 1 57  ? -36.61679 -4.91427  16.43095  1.000 93.31697  ? 603  ALA   A CB  1 
ATOM   156  N N   . PHE   A 1 58  ? -38.02361 -2.49156  14.72462  1.000 90.01481  ? 604  PHE   A N   1 
ATOM   157  C CA  . PHE   A 1 58  ? -37.70311 -1.38448  13.83205  1.000 91.74851  ? 604  PHE   A CA  1 
ATOM   158  C C   . PHE   A 1 58  ? -38.88437 -0.83870  13.03998  1.000 86.44017  ? 604  PHE   A C   1 
ATOM   159  O O   . PHE   A 1 58  ? -38.68416 0.06509   12.22242  1.000 84.99302  ? 604  PHE   A O   1 
ATOM   160  C CB  . PHE   A 1 58  ? -36.60217 -1.81171  12.85275  1.000 98.08678  ? 604  PHE   A CB  1 
ATOM   161  N N   . GLY   A 1 59  ? -40.09812 -1.34808  13.24511  1.000 83.04388  ? 605  GLY   A N   1 
ATOM   162  C CA  . GLY   A 1 59  ? -41.26533 -0.79787  12.59326  1.000 76.75309  ? 605  GLY   A CA  1 
ATOM   163  C C   . GLY   A 1 59  ? -42.39337 -0.65247  13.59260  1.000 72.77729  ? 605  GLY   A C   1 
ATOM   164  O O   . GLY   A 1 59  ? -42.34585 -1.20650  14.69150  1.000 75.75864  ? 605  GLY   A O   1 
ATOM   165  N N   . LYS   A 1 60  ? -43.40927 0.10794   13.19840  1.000 66.50569  ? 606  LYS   A N   1 
ATOM   166  C CA  . LYS   A 1 60  ? -44.56454 0.27556   14.06643  1.000 64.76338  ? 606  LYS   A CA  1 
ATOM   167  C C   . LYS   A 1 60  ? -45.77308 0.65367   13.22649  1.000 63.71319  ? 606  LYS   A C   1 
ATOM   168  O O   . LYS   A 1 60  ? -45.64590 1.16886   12.11418  1.000 64.44503  ? 606  LYS   A O   1 
ATOM   169  C CB  . LYS   A 1 60  ? -44.30740 1.32218   15.15853  1.000 62.20851  ? 606  LYS   A CB  1 
ATOM   170  C CG  . LYS   A 1 60  ? -44.03578 2.73314   14.65780  1.000 62.03139  ? 606  LYS   A CG  1 
ATOM   171  C CD  . LYS   A 1 60  ? -43.73640 3.65645   15.82828  1.000 66.75827  ? 606  LYS   A CD  1 
ATOM   172  C CE  . LYS   A 1 60  ? -43.47305 5.08301   15.37543  1.000 71.49203  ? 606  LYS   A CE  1 
ATOM   173  N NZ  . LYS   A 1 60  ? -43.36758 6.00237   16.54124  1.000 74.24875  ? 606  LYS   A NZ  1 
ATOM   174  N N   . VAL   A 1 61  ? -46.94936 0.35970   13.77028  1.000 58.64230  ? 607  VAL   A N   1 
ATOM   175  C CA  . VAL   A 1 61  ? -48.22548 0.77183   13.20055  1.000 59.33770  ? 607  VAL   A CA  1 
ATOM   176  C C   . VAL   A 1 61  ? -48.88869 1.69486   14.20825  1.000 60.24181  ? 607  VAL   A C   1 
ATOM   177  O O   . VAL   A 1 61  ? -49.08545 1.31109   15.36801  1.000 61.71252  ? 607  VAL   A O   1 
ATOM   178  C CB  . VAL   A 1 61  ? -49.13250 -0.42675  12.88314  1.000 58.20806  ? 607  VAL   A CB  1 
ATOM   179  C CG1 . VAL   A 1 61  ? -50.53400 0.05000   12.54963  1.000 56.27867  ? 607  VAL   A CG1 1 
ATOM   180  C CG2 . VAL   A 1 61  ? -48.56027 -1.23993  11.73484  1.000 57.92147  ? 607  VAL   A CG2 1 
ATOM   181  N N   . VAL   A 1 62  ? -49.22676 2.90752   13.77822  1.000 59.00575  ? 608  VAL   A N   1 
ATOM   182  C CA  . VAL   A 1 62  ? -49.84692 3.89069   14.65587  1.000 59.69029  ? 608  VAL   A CA  1 
ATOM   183  C C   . VAL   A 1 62  ? -51.24573 4.21406   14.14977  1.000 56.33612  ? 608  VAL   A C   1 
ATOM   184  O O   . VAL   A 1 62  ? -51.50311 4.23689   12.93986  1.000 52.95797  ? 608  VAL   A O   1 
ATOM   185  C CB  . VAL   A 1 62  ? -49.00367 5.17868   14.77695  1.000 64.03843  ? 608  VAL   A CB  1 
ATOM   186  C CG1 . VAL   A 1 62  ? -47.57188 4.84419   15.16660  1.000 69.40775  ? 608  VAL   A CG1 1 
ATOM   187  C CG2 . VAL   A 1 62  ? -49.04836 5.97738   13.49222  1.000 63.06508  ? 608  VAL   A CG2 1 
ATOM   188  N N   . GLU   A 1 63  ? -52.14906 4.44566   15.09459  1.000 56.22174  ? 609  GLU   A N   1 
ATOM   189  C CA  . GLU   A 1 63  ? -53.45621 4.99872   14.78609  1.000 58.99746  ? 609  GLU   A CA  1 
ATOM   190  C C   . GLU   A 1 63  ? -53.30294 6.43917   14.31282  1.000 59.56413  ? 609  GLU   A C   1 
ATOM   191  O O   . GLU   A 1 63  ? -52.36829 7.13990   14.70497  1.000 57.00687  ? 609  GLU   A O   1 
ATOM   192  C CB  . GLU   A 1 63  ? -54.33200 4.92213   16.03359  1.000 66.24414  ? 609  GLU   A CB  1 
ATOM   193  C CG  . GLU   A 1 63  ? -55.81483 5.09998   15.83897  1.000 79.85075  ? 609  GLU   A CG  1 
ATOM   194  C CD  . GLU   A 1 63  ? -56.55786 4.94368   17.15011  1.000 94.13056  ? 609  GLU   A CD  1 
ATOM   195  O OE1 . GLU   A 1 63  ? -56.51162 5.88121   17.97214  1.000 102.35333 ? 609  GLU   A OE1 1 
ATOM   196  O OE2 . GLU   A 1 63  ? -57.15812 3.87206   17.37667  1.000 99.04573  ? 609  GLU   A OE2 1 
ATOM   197  N N   . GLY   A 1 64  ? -54.21994 6.88342   13.46285  1.000 57.02153  ? 610  GLY   A N   1 
ATOM   198  C CA  . GLY   A 1 64  ? -54.09769 8.21077   12.90643  1.000 56.53046  ? 610  GLY   A CA  1 
ATOM   199  C C   . GLY   A 1 64  ? -55.39603 8.72317   12.32427  1.000 55.37146  ? 610  GLY   A C   1 
ATOM   200  O O   . GLY   A 1 64  ? -56.40648 8.01719   12.28018  1.000 49.19609  ? 610  GLY   A O   1 
ATOM   201  N N   . THR   A 1 65  ? -55.35161 9.98183   11.88985  1.000 55.60313  ? 611  THR   A N   1 
ATOM   202  C CA  . THR   A 1 65  ? -56.46624 10.63877  11.21901  1.000 55.12862  ? 611  THR   A CA  1 
ATOM   203  C C   . THR   A 1 65  ? -55.94206 11.30696  9.95657   1.000 57.27006  ? 611  THR   A C   1 
ATOM   204  O O   . THR   A 1 65  ? -54.91687 11.99418  9.99625   1.000 57.03142  ? 611  THR   A O   1 
ATOM   205  C CB  . THR   A 1 65  ? -57.14096 11.67978  12.12196  1.000 53.20344  ? 611  THR   A CB  1 
ATOM   206  O OG1 . THR   A 1 65  ? -57.45597 11.08907  13.38838  1.000 54.10948  ? 611  THR   A OG1 1 
ATOM   207  C CG2 . THR   A 1 65  ? -58.42072 12.19283  11.47804  1.000 50.39089  ? 611  THR   A CG2 1 
ATOM   208  N N   . ALA   A 1 66  ? -56.64063 11.10413  8.84367   1.000 54.29749  ? 612  ALA   A N   1 
ATOM   209  C CA  . ALA   A 1 66  ? -56.25547 11.65825  7.55359   1.000 53.43069  ? 612  ALA   A CA  1 
ATOM   210  C C   . ALA   A 1 66  ? -57.29686 12.66904  7.09303   1.000 54.30230  ? 612  ALA   A C   1 
ATOM   211  O O   . ALA   A 1 66  ? -58.49643 12.37750  7.10031   1.000 49.94622  ? 612  ALA   A O   1 
ATOM   212  C CB  . ALA   A 1 66  ? -56.08829 10.54919  6.51125   1.000 53.13506  ? 612  ALA   A CB  1 
ATOM   213  N N   . TYR   A 1 67  ? -56.83379 13.85114  6.69182   1.000 53.11346  ? 613  TYR   A N   1 
ATOM   214  C CA  . TYR   A 1 67  ? -57.69548 14.94346  6.24903   1.000 55.41100  ? 613  TYR   A CA  1 
ATOM   215  C C   . TYR   A 1 67  ? -57.56306 15.10377  4.74090   1.000 59.10561  ? 613  TYR   A C   1 
ATOM   216  O O   . TYR   A 1 67  ? -56.47261 15.39880  4.23969   1.000 62.35679  ? 613  TYR   A O   1 
ATOM   217  C CB  . TYR   A 1 67  ? -57.32995 16.25153  6.95509   1.000 54.88958  ? 613  TYR   A CB  1 
ATOM   218  C CG  . TYR   A 1 67  ? -57.37176 16.16369  8.45803   1.000 58.89818  ? 613  TYR   A CG  1 
ATOM   219  C CD1 . TYR   A 1 67  ? -58.48737 15.65862  9.11036   1.000 58.62846  ? 613  TYR   A CD1 1 
ATOM   220  C CD2 . TYR   A 1 67  ? -56.28522 16.56354  9.22415   1.000 59.28135  ? 613  TYR   A CD2 1 
ATOM   221  C CE1 . TYR   A 1 67  ? -58.52869 15.56958  10.48488  1.000 60.29686  ? 613  TYR   A CE1 1 
ATOM   222  C CE2 . TYR   A 1 67  ? -56.31682 16.47761  10.60074  1.000 61.43284  ? 613  TYR   A CE2 1 
ATOM   223  C CZ  . TYR   A 1 67  ? -57.44094 15.98043  11.22531  1.000 62.50194  ? 613  TYR   A CZ  1 
ATOM   224  O OH  . TYR   A 1 67  ? -57.47426 15.89283  12.59783  1.000 69.24800  ? 613  TYR   A OH  1 
ATOM   225  N N   . GLY   A 1 68  ? -58.66765 14.91982  4.02463   1.000 56.51255  ? 614  GLY   A N   1 
ATOM   226  C CA  . GLY   A 1 68  ? -58.65651 15.04442  2.57957   1.000 60.51125  ? 614  GLY   A CA  1 
ATOM   227  C C   . GLY   A 1 68  ? -58.17857 13.82261  1.82955   1.000 61.78889  ? 614  GLY   A C   1 
ATOM   228  O O   . GLY   A 1 68  ? -57.87277 13.92831  0.63566   1.000 64.19994  ? 614  GLY   A O   1 
ATOM   229  N N   . LEU   A 1 69  ? -58.09296 12.66552  2.49349   1.000 56.62513  ? 615  LEU   A N   1 
ATOM   230  C CA  . LEU   A 1 69  ? -57.71271 11.42022  1.83335   1.000 60.60874  ? 615  LEU   A CA  1 
ATOM   231  C C   . LEU   A 1 69  ? -58.84767 10.83039  1.00507   1.000 61.40359  ? 615  LEU   A C   1 
ATOM   232  O O   . LEU   A 1 69  ? -58.58685 10.03555  0.09658   1.000 67.95329  ? 615  LEU   A O   1 
ATOM   233  C CB  . LEU   A 1 69  ? -57.24241 10.40769  2.87909   1.000 62.85430  ? 615  LEU   A CB  1 
ATOM   234  C CG  . LEU   A 1 69  ? -56.67450 9.05419   2.45769   1.000 67.76074  ? 615  LEU   A CG  1 
ATOM   235  C CD1 . LEU   A 1 69  ? -55.34271 9.20280   1.72614   1.000 69.19792  ? 615  LEU   A CD1 1 
ATOM   236  C CD2 . LEU   A 1 69  ? -56.51903 8.19098   3.69015   1.000 69.47898  ? 615  LEU   A CD2 1 
ATOM   237  N N   . SER   A 1 70  ? -60.09366 11.19657  1.30497   1.000 60.74102  ? 616  SER   A N   1 
ATOM   238  C CA  . SER   A 1 70  ? -61.25263 10.88323  0.47951   1.000 65.32291  ? 616  SER   A CA  1 
ATOM   239  C C   . SER   A 1 70  ? -62.10968 12.13376  0.36265   1.000 64.21770  ? 616  SER   A C   1 
ATOM   240  O O   . SER   A 1 70  ? -62.23509 12.90201  1.32239   1.000 59.97554  ? 616  SER   A O   1 
ATOM   241  C CB  . SER   A 1 70  ? -62.08963 9.73442   1.06375   1.000 66.98042  ? 616  SER   A CB  1 
ATOM   242  O OG  . SER   A 1 70  ? -63.46761 9.88417   0.75714   1.000 74.47655  ? 616  SER   A OG  1 
ATOM   243  N N   . ARG   A 1 71  ? -62.67851 12.34613  -0.82704  1.000 69.27635  ? 617  ARG   A N   1 
ATOM   244  C CA  . ARG   A 1 71  ? -63.61161 13.45279  -1.00854  1.000 71.23487  ? 617  ARG   A CA  1 
ATOM   245  C C   . ARG   A 1 71  ? -64.90516 13.22135  -0.24007  1.000 68.32104  ? 617  ARG   A C   1 
ATOM   246  O O   . ARG   A 1 71  ? -65.54214 14.18398  0.19753   1.000 65.62583  ? 617  ARG   A O   1 
ATOM   247  C CB  . ARG   A 1 71  ? -63.91255 13.65705  -2.49360  1.000 75.64188  ? 617  ARG   A CB  1 
ATOM   248  N N   . SER   A 1 72  ? -65.30155 11.95938  -0.05665  1.000 69.01378  ? 618  SER   A N   1 
ATOM   249  C CA  . SER   A 1 72  ? -66.56639 11.65933  0.60125   1.000 72.12964  ? 618  SER   A CA  1 
ATOM   250  C C   . SER   A 1 72  ? -66.42149 11.58745  2.11689   1.000 67.29939  ? 618  SER   A C   1 
ATOM   251  O O   . SER   A 1 72  ? -67.38116 11.87920  2.83917   1.000 63.53421  ? 618  SER   A O   1 
ATOM   252  C CB  . SER   A 1 72  ? -67.13485 10.34675  0.06647   1.000 75.34874  ? 618  SER   A CB  1 
ATOM   253  O OG  . SER   A 1 72  ? -66.37241 9.24303   0.52750   1.000 76.94041  ? 618  SER   A OG  1 
ATOM   254  N N   . GLN   A 1 73  ? -65.24675 11.19952  2.61638   1.000 65.93208  ? 619  GLN   A N   1 
ATOM   255  C CA  . GLN   A 1 73  ? -64.96948 11.12887  4.05232   1.000 64.14475  ? 619  GLN   A CA  1 
ATOM   256  C C   . GLN   A 1 73  ? -63.76539 12.00934  4.36016   1.000 59.26475  ? 619  GLN   A C   1 
ATOM   257  O O   . GLN   A 1 73  ? -62.64414 11.50976  4.52449   1.000 58.58193  ? 619  GLN   A O   1 
ATOM   258  C CB  . GLN   A 1 73  ? -64.70239 9.69341   4.50416   1.000 65.91239  ? 619  GLN   A CB  1 
ATOM   259  C CG  . GLN   A 1 73  ? -65.61403 8.63672   3.91511   1.000 75.38933  ? 619  GLN   A CG  1 
ATOM   260  C CD  . GLN   A 1 73  ? -65.18484 7.24187   4.32595   1.000 78.13924  ? 619  GLN   A CD  1 
ATOM   261  O OE1 . GLN   A 1 73  ? -64.95984 6.97650   5.50512   1.000 77.26281  ? 619  GLN   A OE1 1 
ATOM   262  N NE2 . GLN   A 1 73  ? -65.04737 6.34948   3.35255   1.000 79.65815  ? 619  GLN   A NE2 1 
ATOM   263  N N   . PRO   A 1 74  ? -63.95945 13.32865  4.45746   1.000 56.67309  ? 620  PRO   A N   1 
ATOM   264  C CA  . PRO   A 1 74  ? -62.80625 14.23215  4.62774   1.000 55.00873  ? 620  PRO   A CA  1 
ATOM   265  C C   . PRO   A 1 74  ? -62.06689 14.07966  5.95312   1.000 54.79832  ? 620  PRO   A C   1 
ATOM   266  O O   . PRO   A 1 74  ? -60.96951 14.63907  6.08746   1.000 52.45474  ? 620  PRO   A O   1 
ATOM   267  C CB  . PRO   A 1 74  ? -63.43312 15.62729  4.50288   1.000 55.66678  ? 620  PRO   A CB  1 
ATOM   268  C CG  . PRO   A 1 74  ? -64.87334 15.42625  4.84676   1.000 55.78501  ? 620  PRO   A CG  1 
ATOM   269  C CD  . PRO   A 1 74  ? -65.23021 14.06569  4.34321   1.000 56.04290  ? 620  PRO   A CD  1 
ATOM   270  N N   . VAL   A 1 75  ? -62.61764 13.35130  6.92441   1.000 53.47608  ? 621  VAL   A N   1 
ATOM   271  C CA  . VAL   A 1 75  ? -62.00334 13.15375  8.24031   1.000 53.74051  ? 621  VAL   A CA  1 
ATOM   272  C C   . VAL   A 1 75  ? -62.11826 11.66721  8.54601   1.000 56.99640  ? 621  VAL   A C   1 
ATOM   273  O O   . VAL   A 1 75  ? -63.16511 11.20644  9.01706   1.000 61.62494  ? 621  VAL   A O   1 
ATOM   274  C CB  . VAL   A 1 75  ? -62.67972 13.98639  9.33584   1.000 53.66983  ? 621  VAL   A CB  1 
ATOM   275  C CG1 . VAL   A 1 75  ? -62.01352 13.75011  10.68803  1.000 54.25455  ? 621  VAL   A CG1 1 
ATOM   276  C CG2 . VAL   A 1 75  ? -62.68208 15.46330  8.98441   1.000 46.14642  ? 621  VAL   A CG2 1 
ATOM   277  N N   . MET   A 1 76  ? -61.05565 10.90775  8.28662   1.000 53.94649  ? 622  MET   A N   1 
ATOM   278  C CA  . MET   A 1 76  ? -61.17029 9.46071   8.37066   1.000 60.11299  ? 622  MET   A CA  1 
ATOM   279  C C   . MET   A 1 76  ? -60.03290 8.84530   9.17748   1.000 56.59364  ? 622  MET   A C   1 
ATOM   280  O O   . MET   A 1 76  ? -58.86150 9.20211   9.01479   1.000 54.63836  ? 622  MET   A O   1 
ATOM   281  C CB  . MET   A 1 76  ? -61.27368 8.84032   6.96294   1.000 66.21013  ? 622  MET   A CB  1 
ATOM   282  C CG  . MET   A 1 76  ? -59.99478 8.30686   6.35229   1.000 65.36667  ? 622  MET   A CG  1 
ATOM   283  S SD  . MET   A 1 76  ? -60.41477 7.06995   5.11097   1.000 71.72031  ? 622  MET   A SD  1 
ATOM   284  C CE  . MET   A 1 76  ? -61.47932 8.03428   4.03712   1.000 60.75673  ? 622  MET   A CE  1 
ATOM   285  N N   . LYS   A 1 77  ? -60.41756 7.92678   10.06513  1.000 55.21250  ? 623  LYS   A N   1 
ATOM   286  C CA  . LYS   A 1 77  ? -59.49271 7.23489   10.95077  1.000 54.95707  ? 623  LYS   A CA  1 
ATOM   287  C C   . LYS   A 1 77  ? -58.70437 6.19308   10.16579  1.000 51.78655  ? 623  LYS   A C   1 
ATOM   288  O O   . LYS   A 1 77  ? -59.26914 5.43858   9.36543   1.000 55.59446  ? 623  LYS   A O   1 
ATOM   289  C CB  . LYS   A 1 77  ? -60.27799 6.57664   12.08588  1.000 54.43121  ? 623  LYS   A CB  1 
ATOM   290  C CG  . LYS   A 1 77  ? -59.44770 5.95826   13.18628  1.000 60.56269  ? 623  LYS   A CG  1 
ATOM   291  C CD  . LYS   A 1 77  ? -60.33340 5.61459   14.37235  1.000 69.04468  ? 623  LYS   A CD  1 
ATOM   292  C CE  . LYS   A 1 77  ? -59.51841 5.05667   15.52307  1.000 70.26610  ? 623  LYS   A CE  1 
ATOM   293  N NZ  . LYS   A 1 77  ? -60.35512 4.57331   16.65697  1.000 73.02835  ? 623  LYS   A NZ  1 
ATOM   294  N N   . VAL   A 1 78  ? -57.39132 6.15847   10.38661  1.000 51.80161  ? 624  VAL   A N   1 
ATOM   295  C CA  . VAL   A 1 78  ? -56.49325 5.29701   9.63412   1.000 55.17052  ? 624  VAL   A CA  1 
ATOM   296  C C   . VAL   A 1 78  ? -55.49989 4.64307   10.58521  1.000 55.99694  ? 624  VAL   A C   1 
ATOM   297  O O   . VAL   A 1 78  ? -55.35140 5.02972   11.74581  1.000 57.61909  ? 624  VAL   A O   1 
ATOM   298  C CB  . VAL   A 1 78  ? -55.73366 6.06898   8.53262   1.000 50.87336  ? 624  VAL   A CB  1 
ATOM   299  C CG1 . VAL   A 1 78  ? -56.70767 6.67780   7.52301   1.000 51.88255  ? 624  VAL   A CG1 1 
ATOM   300  C CG2 . VAL   A 1 78  ? -54.85798 7.13996   9.15657   1.000 49.82985  ? 624  VAL   A CG2 1 
ATOM   301  N N   . ALA   A 1 79  ? -54.82612 3.62870   10.06493  1.000 53.33227  ? 625  ALA   A N   1 
ATOM   302  C CA  . ALA   A 1 79  ? -53.62798 3.07097   10.66383  1.000 52.48736  ? 625  ALA   A CA  1 
ATOM   303  C C   . ALA   A 1 79  ? -52.46250 3.33166   9.72130   1.000 54.75292  ? 625  ALA   A C   1 
ATOM   304  O O   . ALA   A 1 79  ? -52.62859 3.33151   8.49842   1.000 56.73606  ? 625  ALA   A O   1 
ATOM   305  C CB  . ALA   A 1 79  ? -53.77817 1.57341   10.91907  1.000 46.44627  ? 625  ALA   A CB  1 
ATOM   306  N N   . VAL   A 1 80  ? -51.28449 3.57440   10.29297  1.000 54.93370  ? 626  VAL   A N   1 
ATOM   307  C CA  . VAL   A 1 80  ? -50.11158 3.99280   9.53134   1.000 53.04361  ? 626  VAL   A CA  1 
ATOM   308  C C   . VAL   A 1 80  ? -48.92819 3.13418   9.95526   1.000 55.68777  ? 626  VAL   A C   1 
ATOM   309  O O   . VAL   A 1 80  ? -48.55566 3.12787   11.13432  1.000 57.92818  ? 626  VAL   A O   1 
ATOM   310  C CB  . VAL   A 1 80  ? -49.79069 5.48453   9.74200   1.000 55.04782  ? 626  VAL   A CB  1 
ATOM   311  C CG1 . VAL   A 1 80  ? -48.68540 5.93056   8.79934   1.000 56.73903  ? 626  VAL   A CG1 1 
ATOM   312  C CG2 . VAL   A 1 80  ? -51.03514 6.34667   9.56360   1.000 56.16846  ? 626  VAL   A CG2 1 
ATOM   313  N N   . LYS   A 1 81  ? -48.33699 2.41538   9.00372   1.000 54.72737  ? 627  LYS   A N   1 
ATOM   314  C CA  . LYS   A 1 81  ? -47.09831 1.69655   9.25949   1.000 58.46392  ? 627  LYS   A CA  1 
ATOM   315  C C   . LYS   A 1 81  ? -45.91883 2.57471   8.87106   1.000 63.40057  ? 627  LYS   A C   1 
ATOM   316  O O   . LYS   A 1 81  ? -45.90636 3.17595   7.79235   1.000 63.47068  ? 627  LYS   A O   1 
ATOM   317  C CB  . LYS   A 1 81  ? -47.03273 0.37800   8.49025   1.000 58.77616  ? 627  LYS   A CB  1 
ATOM   318  C CG  . LYS   A 1 81  ? -45.72409 -0.37382  8.71327   1.000 62.60516  ? 627  LYS   A CG  1 
ATOM   319  C CD  . LYS   A 1 81  ? -45.70574 -1.71706  8.01149   1.000 67.59803  ? 627  LYS   A CD  1 
ATOM   320  C CE  . LYS   A 1 81  ? -46.65855 -2.69310  8.66845   1.000 70.30404  ? 627  LYS   A CE  1 
ATOM   321  N NZ  . LYS   A 1 81  ? -46.60883 -4.03743  8.03733   1.000 75.96536  ? 627  LYS   A NZ  1 
ATOM   322  N N   . MET   A 1 82  ? -44.92637 2.63483   9.74944   1.000 64.39742  ? 628  MET   A N   1 
ATOM   323  C CA  . MET   A 1 82  ? -43.76254 3.47660   9.54217   1.000 70.86519  ? 628  MET   A CA  1 
ATOM   324  C C   . MET   A 1 82  ? -42.57433 2.82564   10.22810  1.000 75.94875  ? 628  MET   A C   1 
ATOM   325  O O   . MET   A 1 82  ? -42.73131 1.96285   11.09461  1.000 74.36587  ? 628  MET   A O   1 
ATOM   326  C CB  . MET   A 1 82  ? -44.00553 4.88746   10.08601  1.000 72.61095  ? 628  MET   A CB  1 
ATOM   327  C CG  . MET   A 1 82  ? -44.55836 4.88836   11.50258  1.000 76.25121  ? 628  MET   A CG  1 
ATOM   328  S SD  . MET   A 1 82  ? -44.97312 6.53028   12.11047  1.000 79.11250  ? 628  MET   A SD  1 
ATOM   329  C CE  . MET   A 1 82  ? -43.36645 7.31475   12.06579  1.000 85.56813  ? 628  MET   A CE  1 
ATOM   330  N N   . LEU   A 1 83  ? -41.38004 3.24579   9.83402   1.000 79.13902  ? 629  LEU   A N   1 
ATOM   331  C CA  . LEU   A 1 83  ? -40.18137 2.72340   10.46556  1.000 80.59012  ? 629  LEU   A CA  1 
ATOM   332  C C   . LEU   A 1 83  ? -39.86084 3.49848   11.73291  1.000 80.61713  ? 629  LEU   A C   1 
ATOM   333  O O   . LEU   A 1 83  ? -40.21602 4.67068   11.87934  1.000 79.18629  ? 629  LEU   A O   1 
ATOM   334  C CB  . LEU   A 1 83  ? -38.98715 2.79467   9.52153   1.000 83.42554  ? 629  LEU   A CB  1 
ATOM   335  C CG  . LEU   A 1 83  ? -39.03189 1.90004   8.29212   1.000 82.94274  ? 629  LEU   A CG  1 
ATOM   336  C CD1 . LEU   A 1 83  ? -37.69048 1.97941   7.62537   1.000 90.00646  ? 629  LEU   A CD1 1 
ATOM   337  C CD2 . LEU   A 1 83  ? -39.37134 0.46741   8.67329   1.000 81.50043  ? 629  LEU   A CD2 1 
ATOM   338  N N   . LYS   A 1 84  ? -39.18795 2.82598   12.65260  1.000 84.07304  ? 630  LYS   A N   1 
ATOM   339  C CA  . LYS   A 1 84  ? -38.60926 3.49061   13.80244  1.000 92.14091  ? 630  LYS   A CA  1 
ATOM   340  C C   . LYS   A 1 84  ? -37.24435 4.05750   13.42375  1.000 100.34042 ? 630  LYS   A C   1 
ATOM   341  O O   . LYS   A 1 84  ? -36.65902 3.65978   12.41251  1.000 101.30363 ? 630  LYS   A O   1 
ATOM   342  C CB  . LYS   A 1 84  ? -38.49156 2.50957   14.96650  1.000 94.85914  ? 630  LYS   A CB  1 
ATOM   343  C CG  . LYS   A 1 84  ? -39.82163 1.89974   15.38502  1.000 92.75684  ? 630  LYS   A CG  1 
ATOM   344  C CD  . LYS   A 1 84  ? -39.94795 1.77930   16.89979  1.000 94.50319  ? 630  LYS   A CD  1 
ATOM   345  C CE  . LYS   A 1 84  ? -39.34065 0.48985   17.42611  1.000 97.33163  ? 630  LYS   A CE  1 
ATOM   346  N NZ  . LYS   A 1 84  ? -39.74468 0.24152   18.84071  1.000 98.58365  ? 630  LYS   A NZ  1 
ATOM   347  N N   . PRO   A 1 85  ? -36.72123 5.01150   14.20095  1.000 107.38198 ? 631  PRO   A N   1 
ATOM   348  C CA  . PRO   A 1 85  ? -35.36275 5.50213   13.91407  1.000 116.05034 ? 631  PRO   A CA  1 
ATOM   349  C C   . PRO   A 1 85  ? -34.32737 4.39658   13.93445  1.000 120.41087 ? 631  PRO   A C   1 
ATOM   350  O O   . PRO   A 1 85  ? -33.31271 4.48668   13.23140  1.000 124.15992 ? 631  PRO   A O   1 
ATOM   351  C CB  . PRO   A 1 85  ? -35.11217 6.52573   15.03053  1.000 116.88248 ? 631  PRO   A CB  1 
ATOM   352  C CG  . PRO   A 1 85  ? -36.46424 6.93245   15.49117  1.000 110.32819 ? 631  PRO   A CG  1 
ATOM   353  C CD  . PRO   A 1 85  ? -37.33705 5.72454   15.33385  1.000 104.85894 ? 631  PRO   A CD  1 
ATOM   354  N N   . THR   A 1 86  ? -34.57543 3.34123   14.71284  1.000 121.56376 ? 632  THR   A N   1 
ATOM   355  C CA  . THR   A 1 86  ? -33.62084 2.24840   14.84308  1.000 125.25311 ? 632  THR   A CA  1 
ATOM   356  C C   . THR   A 1 86  ? -33.36756 1.54977   13.51272  1.000 121.42522 ? 632  THR   A C   1 
ATOM   357  O O   . THR   A 1 86  ? -32.27227 1.02144   13.29082  1.000 124.99410 ? 632  THR   A O   1 
ATOM   358  C CB  . THR   A 1 86  ? -34.13807 1.24168   15.87417  1.000 128.73511 ? 632  THR   A CB  1 
ATOM   359  O OG1 . THR   A 1 86  ? -34.85262 1.93612   16.90369  1.000 129.76394 ? 632  THR   A OG1 1 
ATOM   360  C CG2 . THR   A 1 86  ? -32.98417 0.47517   16.49829  1.000 134.08972 ? 632  THR   A CG2 1 
ATOM   361  N N   . ALA   A 1 87  ? -34.35346 1.55162   12.61662  1.000 112.39062 ? 633  ALA   A N   1 
ATOM   362  C CA  . ALA   A 1 87  ? -34.30426 0.69967   11.43523  1.000 108.03600 ? 633  ALA   A CA  1 
ATOM   363  C C   . ALA   A 1 87  ? -33.14800 1.07505   10.51607  1.000 110.68761 ? 633  ALA   A C   1 
ATOM   364  O O   . ALA   A 1 87  ? -32.80323 2.24980   10.36479  1.000 108.94779 ? 633  ALA   A O   1 
ATOM   365  C CB  . ALA   A 1 87  ? -35.62575 0.78182   10.67004  1.000 100.61813 ? 633  ALA   A CB  1 
ATOM   366  N N   . ARG   A 1 88  ? -32.55307 0.05889   9.89523   1.000 118.10956 ? 634  ARG   A N   1 
ATOM   367  C CA  . ARG   A 1 88  ? -31.44536 0.24103   8.97175   1.000 128.37518 ? 634  ARG   A CA  1 
ATOM   368  C C   . ARG   A 1 88  ? -31.98649 0.32388   7.54427   1.000 128.22200 ? 634  ARG   A C   1 
ATOM   369  O O   . ARG   A 1 88  ? -33.19864 0.35820   7.31524   1.000 122.71215 ? 634  ARG   A O   1 
ATOM   370  C CB  . ARG   A 1 88  ? -30.43686 -0.89541  9.12966   1.000 137.94285 ? 634  ARG   A CB  1 
ATOM   371  C CG  . ARG   A 1 88  ? -30.29647 -1.42028  10.55089  1.000 142.72626 ? 634  ARG   A CG  1 
ATOM   372  C CD  . ARG   A 1 88  ? -29.70361 -2.82462  10.55032  1.000 150.59604 ? 634  ARG   A CD  1 
ATOM   373  N NE  . ARG   A 1 88  ? -30.67789 -3.84041  10.15342  1.000 149.59143 ? 634  ARG   A NE  1 
ATOM   374  C CZ  . ARG   A 1 88  ? -31.00003 -4.89794  10.89313  1.000 149.70595 ? 634  ARG   A CZ  1 
ATOM   375  N NH1 . ARG   A 1 88  ? -30.41555 -5.09159  12.06778  1.000 152.58035 ? 634  ARG   A NH1 1 
ATOM   376  N NH2 . ARG   A 1 88  ? -31.89848 -5.76953  10.45474  1.000 147.89955 ? 634  ARG   A NH2 1 
ATOM   377  N N   . SER   A 1 89  ? -31.08341 0.34079   6.56094   1.000 122.26077 ? 635  SER   A N   1 
ATOM   378  C CA  . SER   A 1 89  ? -31.51042 0.45423   5.16924   1.000 122.01068 ? 635  SER   A CA  1 
ATOM   379  C C   . SER   A 1 89  ? -32.23173 -0.79908  4.68838   1.000 119.02859 ? 635  SER   A C   1 
ATOM   380  O O   . SER   A 1 89  ? -33.11673 -0.70904  3.82964   1.000 114.61630 ? 635  SER   A O   1 
ATOM   381  C CB  . SER   A 1 89  ? -30.31032 0.74088   4.27210   1.000 127.06355 ? 635  SER   A CB  1 
ATOM   382  O OG  . SER   A 1 89  ? -29.41104 -0.35401  4.26434   1.000 129.26024 ? 635  SER   A OG  1 
ATOM   383  N N   . SER   A 1 90  ? -31.86743 -1.97079  5.21701   1.000 122.97511 ? 636  SER   A N   1 
ATOM   384  C CA  . SER   A 1 90  ? -32.54001 -3.20269  4.81312   1.000 126.08361 ? 636  SER   A CA  1 
ATOM   385  C C   . SER   A 1 90  ? -34.01920 -3.15918  5.16598   1.000 124.37997 ? 636  SER   A C   1 
ATOM   386  O O   . SER   A 1 90  ? -34.86949 -3.60529  4.38528   1.000 121.89399 ? 636  SER   A O   1 
ATOM   387  C CB  . SER   A 1 90  ? -31.87378 -4.40841  5.47369   1.000 126.78381 ? 636  SER   A CB  1 
ATOM   388  O OG  . SER   A 1 90  ? -32.25134 -4.50877  6.83618   1.000 122.18407 ? 636  SER   A OG  1 
ATOM   389  N N   . GLU   A 1 91  ? -34.34224 -2.61886  6.33893   1.000 125.49784 ? 637  GLU   A N   1 
ATOM   390  C CA  . GLU   A 1 91  ? -35.72428 -2.52160  6.78240   1.000 121.64944 ? 637  GLU   A CA  1 
ATOM   391  C C   . GLU   A 1 91  ? -36.47422 -1.38276  6.10542   1.000 116.68077 ? 637  GLU   A C   1 
ATOM   392  O O   . GLU   A 1 91  ? -37.70986 -1.40829  6.06593   1.000 119.77159 ? 637  GLU   A O   1 
ATOM   393  C CB  . GLU   A 1 91  ? -35.74771 -2.37712  8.30328   1.000 126.88830 ? 637  GLU   A CB  1 
ATOM   394  C CG  . GLU   A 1 91  ? -35.10219 -3.57865  8.98886   1.000 135.27808 ? 637  GLU   A CG  1 
ATOM   395  C CD  . GLU   A 1 91  ? -34.68299 -3.31352  10.41603  1.000 139.53952 ? 637  GLU   A CD  1 
ATOM   396  O OE1 . GLU   A 1 91  ? -33.88921 -2.37759  10.64785  1.000 142.23672 ? 637  GLU   A OE1 1 
ATOM   397  O OE2 . GLU   A 1 91  ? -35.14195 -4.05483  11.30681  1.000 139.28065 ? 637  GLU   A OE2 1 
ATOM   398  N N   . LYS   A 1 92  ? -35.75265 -0.40132  5.55614   1.000 110.82135 ? 638  LYS   A N   1 
ATOM   399  C CA  . LYS   A 1 92  ? -36.38001 0.65161   4.76360   1.000 101.68457 ? 638  LYS   A CA  1 
ATOM   400  C C   . LYS   A 1 92  ? -36.70827 0.16929   3.35877   1.000 98.05371  ? 638  LYS   A C   1 
ATOM   401  O O   . LYS   A 1 92  ? -37.74546 0.54155   2.79729   1.000 97.39330  ? 638  LYS   A O   1 
ATOM   402  C CB  . LYS   A 1 92  ? -35.47458 1.88116   4.70001   1.000 100.85431 ? 638  LYS   A CB  1 
ATOM   403  N N   . GLN   A 1 93  ? -35.83162 -0.65055  2.77528   1.000 97.49043  ? 639  GLN   A N   1 
ATOM   404  C CA  . GLN   A 1 93  ? -36.11799 -1.22788  1.46690   1.000 96.33059  ? 639  GLN   A CA  1 
ATOM   405  C C   . GLN   A 1 93  ? -37.35097 -2.11839  1.52168   1.000 91.45869  ? 639  GLN   A C   1 
ATOM   406  O O   . GLN   A 1 93  ? -38.15964 -2.13393  0.58654   1.000 87.56917  ? 639  GLN   A O   1 
ATOM   407  C CB  . GLN   A 1 93  ? -34.90910 -2.01802  0.96793   1.000 97.97440  ? 639  GLN   A CB  1 
ATOM   408  N N   . ALA   A 1 94  ? -37.51583 -2.85824  2.62007   1.000 88.52231  ? 640  ALA   A N   1 
ATOM   409  C CA  . ALA   A 1 94  ? -38.65260 -3.76243  2.75191   1.000 86.01845  ? 640  ALA   A CA  1 
ATOM   410  C C   . ALA   A 1 94  ? -39.96922 -3.00576  2.85729   1.000 84.69300  ? 640  ALA   A C   1 
ATOM   411  O O   . ALA   A 1 94  ? -41.00461 -3.49810  2.39360   1.000 83.88771  ? 640  ALA   A O   1 
ATOM   412  C CB  . ALA   A 1 94  ? -38.46265 -4.67093  3.96556   1.000 82.70116  ? 640  ALA   A CB  1 
ATOM   413  N N   . LEU   A 1 95  ? -39.95437 -1.81482  3.45884   1.000 86.93019  ? 641  LEU   A N   1 
ATOM   414  C CA  . LEU   A 1 95  ? -41.18472 -1.03832  3.56577   1.000 81.84225  ? 641  LEU   A CA  1 
ATOM   415  C C   . LEU   A 1 95  ? -41.60869 -0.49532  2.20743   1.000 85.12053  ? 641  LEU   A C   1 
ATOM   416  O O   . LEU   A 1 95  ? -42.80036 -0.49502  1.87847   1.000 83.64336  ? 641  LEU   A O   1 
ATOM   417  C CB  . LEU   A 1 95  ? -41.00955 0.09899   4.57170   1.000 80.63292  ? 641  LEU   A CB  1 
ATOM   418  C CG  . LEU   A 1 95  ? -42.30309 0.72870   5.08832   1.000 75.04634  ? 641  LEU   A CG  1 
ATOM   419  C CD1 . LEU   A 1 95  ? -43.15738 -0.31721  5.78314   1.000 73.93836  ? 641  LEU   A CD1 1 
ATOM   420  C CD2 . LEU   A 1 95  ? -42.00069 1.88855   6.02773   1.000 72.09409  ? 641  LEU   A CD2 1 
ATOM   421  N N   . MET   A 1 96  ? -40.64706 -0.03931  1.40002   1.000 87.97752  ? 642  MET   A N   1 
ATOM   422  C CA  . MET   A 1 96  ? -40.97857 0.45487   0.06713   1.000 88.54257  ? 642  MET   A CA  1 
ATOM   423  C C   . MET   A 1 96  ? -41.49043 -0.67107  -0.82485  1.000 85.74077  ? 642  MET   A C   1 
ATOM   424  O O   . MET   A 1 96  ? -42.42795 -0.47504  -1.60670  1.000 83.07633  ? 642  MET   A O   1 
ATOM   425  C CB  . MET   A 1 96  ? -39.76147 1.13931   -0.55708  1.000 96.89941  ? 642  MET   A CB  1 
ATOM   426  C CG  . MET   A 1 96  ? -39.98834 1.68738   -1.95743  1.000 105.52363 ? 642  MET   A CG  1 
ATOM   427  S SD  . MET   A 1 96  ? -41.47291 2.69960   -2.09148  1.000 107.73229 ? 642  MET   A SD  1 
ATOM   428  C CE  . MET   A 1 96  ? -41.13285 3.96765   -0.87586  1.000 104.77282 ? 642  MET   A CE  1 
ATOM   429  N N   . SER   A 1 97  ? -40.89684 -1.86326  -0.71149  1.000 86.95080  ? 643  SER   A N   1 
ATOM   430  C CA  . SER   A 1 97  ? -41.37055 -3.00560  -1.48884  1.000 90.69533  ? 643  SER   A CA  1 
ATOM   431  C C   . SER   A 1 97  ? -42.75311 -3.45365  -1.02692  1.000 84.31171  ? 643  SER   A C   1 
ATOM   432  O O   . SER   A 1 97  ? -43.60263 -3.81300  -1.85153  1.000 84.38739  ? 643  SER   A O   1 
ATOM   433  C CB  . SER   A 1 97  ? -40.36938 -4.15833  -1.39661  1.000 95.67022  ? 643  SER   A CB  1 
ATOM   434  O OG  . SER   A 1 97  ? -40.12635 -4.52913  -0.04984  1.000 96.31023  ? 643  SER   A OG  1 
ATOM   435  N N   . GLU   A 1 98  ? -42.99385 -3.44357  0.28723   1.000 81.62247  ? 644  GLU   A N   1 
ATOM   436  C CA  . GLU   A 1 98  ? -44.32021 -3.76296  0.80731   1.000 77.44486  ? 644  GLU   A CA  1 
ATOM   437  C C   . GLU   A 1 98  ? -45.37264 -2.83741  0.21332   1.000 74.57160  ? 644  GLU   A C   1 
ATOM   438  O O   . GLU   A 1 98  ? -46.44221 -3.28597  -0.21827  1.000 71.60755  ? 644  GLU   A O   1 
ATOM   439  C CB  . GLU   A 1 98  ? -44.31783 -3.66582  2.33286   1.000 77.62964  ? 644  GLU   A CB  1 
ATOM   440  C CG  . GLU   A 1 98  ? -45.68064 -3.84910  2.98048   1.000 78.30177  ? 644  GLU   A CG  1 
ATOM   441  C CD  . GLU   A 1 98  ? -45.62749 -3.72053  4.48903   1.000 78.28521  ? 644  GLU   A CD  1 
ATOM   442  O OE1 . GLU   A 1 98  ? -44.50714 -3.71492  5.04265   1.000 80.09018  ? 644  GLU   A OE1 1 
ATOM   443  O OE2 . GLU   A 1 98  ? -46.69907 -3.62483  5.12232   1.000 74.28238  ? 644  GLU   A OE2 1 
ATOM   444  N N   . LEU   A 1 99  ? -45.08178 -1.53505  0.18148   1.000 72.35197  ? 645  LEU   A N   1 
ATOM   445  C CA  . LEU   A 1 99  ? -45.99115 -0.59103  -0.45715  1.000 66.82265  ? 645  LEU   A CA  1 
ATOM   446  C C   . LEU   A 1 99  ? -46.17690 -0.92971  -1.93141  1.000 66.35854  ? 645  LEU   A C   1 
ATOM   447  O O   . LEU   A 1 99  ? -47.30212 -0.92970  -2.44251  1.000 63.73700  ? 645  LEU   A O   1 
ATOM   448  C CB  . LEU   A 1 99  ? -45.46556 0.83510   -0.28923  1.000 63.62782  ? 645  LEU   A CB  1 
ATOM   449  C CG  . LEU   A 1 99  ? -46.27214 1.92825   -0.98416  1.000 66.61128  ? 645  LEU   A CG  1 
ATOM   450  C CD1 . LEU   A 1 99  ? -47.66500 2.01875   -0.39223  1.000 61.57917  ? 645  LEU   A CD1 1 
ATOM   451  C CD2 . LEU   A 1 99  ? -45.55080 3.25846   -0.89031  1.000 69.37692  ? 645  LEU   A CD2 1 
ATOM   452  N N   . LYS   A 1 100 ? -45.07772 -1.23879  -2.62734  1.000 68.11092  ? 646  LYS   A N   1 
ATOM   453  C CA  . LYS   A 1 100 ? -45.16166 -1.58819  -4.04313  1.000 73.14273  ? 646  LYS   A CA  1 
ATOM   454  C C   . LYS   A 1 100 ? -46.03603 -2.81652  -4.26537  1.000 73.28807  ? 646  LYS   A C   1 
ATOM   455  O O   . LYS   A 1 100 ? -46.83806 -2.85307  -5.20708  1.000 77.89262  ? 646  LYS   A O   1 
ATOM   456  C CB  . LYS   A 1 100 ? -43.76120 -1.82439  -4.60731  1.000 73.49908  ? 646  LYS   A CB  1 
ATOM   457  N N   . ILE   A 1 101 ? -45.89536 -3.83340  -3.41044  1.000 68.18326  ? 647  ILE   A N   1 
ATOM   458  C CA  . ILE   A 1 101 ? -46.70388 -5.04013  -3.55741  1.000 69.08770  ? 647  ILE   A CA  1 
ATOM   459  C C   . ILE   A 1 101 ? -48.17136 -4.73942  -3.27481  1.000 66.91496  ? 647  ILE   A C   1 
ATOM   460  O O   . ILE   A 1 101 ? -49.06481 -5.20915  -3.99073  1.000 60.86139  ? 647  ILE   A O   1 
ATOM   461  C CB  . ILE   A 1 101 ? -46.16815 -6.15670  -2.64246  1.000 69.01361  ? 647  ILE   A CB  1 
ATOM   462  C CG1 . ILE   A 1 101 ? -44.74417 -6.54574  -3.04703  1.000 74.22567  ? 647  ILE   A CG1 1 
ATOM   463  C CG2 . ILE   A 1 101 ? -47.08883 -7.36675  -2.67505  1.000 70.08797  ? 647  ILE   A CG2 1 
ATOM   464  C CD1 . ILE   A 1 101 ? -44.14193 -7.64754  -2.19711  1.000 75.86174  ? 647  ILE   A CD1 1 
ATOM   465  N N   . MET   A 1 102 ? -48.44394 -3.94358  -2.23644  1.000 62.78912  ? 648  MET   A N   1 
ATOM   466  C CA  . MET   A 1 102 ? -49.82676 -3.63635  -1.88296  1.000 65.14584  ? 648  MET   A CA  1 
ATOM   467  C C   . MET   A 1 102 ? -50.52756 -2.85812  -2.98921  1.000 68.87362  ? 648  MET   A C   1 
ATOM   468  O O   . MET   A 1 102 ? -51.71893 -3.07037  -3.24266  1.000 71.16763  ? 648  MET   A O   1 
ATOM   469  C CB  . MET   A 1 102 ? -49.88159 -2.85658  -0.56915  1.000 64.62585  ? 648  MET   A CB  1 
ATOM   470  C CG  . MET   A 1 102 ? -49.58881 -3.69472  0.66194   1.000 67.74923  ? 648  MET   A CG  1 
ATOM   471  S SD  . MET   A 1 102 ? -49.81291 -2.77348  2.19574   1.000 70.49156  ? 648  MET   A SD  1 
ATOM   472  C CE  . MET   A 1 102 ? -51.47180 -3.27153  2.64103   1.000 70.17730  ? 648  MET   A CE  1 
ATOM   473  N N   . THR   A 1 103 ? -49.81265 -1.94806  -3.65694  1.000 69.84082  ? 649  THR   A N   1 
ATOM   474  C CA  . THR   A 1 103 ? -50.42444 -1.21789  -4.76241  1.000 76.01482  ? 649  THR   A CA  1 
ATOM   475  C C   . THR   A 1 103 ? -50.82880 -2.16483  -5.88302  1.000 83.95346  ? 649  THR   A C   1 
ATOM   476  O O   . THR   A 1 103 ? -51.84235 -1.94783  -6.55683  1.000 90.39895  ? 649  THR   A O   1 
ATOM   477  C CB  . THR   A 1 103 ? -49.46497 -0.15474  -5.29942  1.000 78.16578  ? 649  THR   A CB  1 
ATOM   478  O OG1 . THR   A 1 103 ? -48.24778 -0.77834  -5.72563  1.000 84.14102  ? 649  THR   A OG1 1 
ATOM   479  C CG2 . THR   A 1 103 ? -49.15638 0.88270   -4.23651  1.000 72.29737  ? 649  THR   A CG2 1 
ATOM   480  N N   . HIS   A 1 104 ? -50.05326 -3.22681  -6.08877  1.000 87.44900  ? 650  HIS   A N   1 
ATOM   481  C CA  . HIS   A 1 104 ? -50.26406 -4.14297  -7.19960  1.000 94.88527  ? 650  HIS   A CA  1 
ATOM   482  C C   . HIS   A 1 104 ? -51.21725 -5.28271  -6.87409  1.000 89.86408  ? 650  HIS   A C   1 
ATOM   483  O O   . HIS   A 1 104 ? -51.65089 -5.98144  -7.79560  1.000 95.98504  ? 650  HIS   A O   1 
ATOM   484  C CB  . HIS   A 1 104 ? -48.92113 -4.71020  -7.66684  1.000 102.86796 ? 650  HIS   A CB  1 
ATOM   485  C CG  . HIS   A 1 104 ? -47.99278 -3.66946  -8.20686  1.000 113.80393 ? 650  HIS   A CG  1 
ATOM   486  N ND1 . HIS   A 1 104 ? -48.44499 -2.48539  -8.74780  1.000 117.00720 ? 650  HIS   A ND1 1 
ATOM   487  C CD2 . HIS   A 1 104 ? -46.64147 -3.62415  -8.27783  1.000 118.10914 ? 650  HIS   A CD2 1 
ATOM   488  C CE1 . HIS   A 1 104 ? -47.41302 -1.75869  -9.13683  1.000 120.82878 ? 650  HIS   A CE1 1 
ATOM   489  N NE2 . HIS   A 1 104 ? -46.30677 -2.42631  -8.86224  1.000 121.04120 ? 650  HIS   A NE2 1 
ATOM   490  N N   . LEU   A 1 105 ? -51.55666 -5.49147  -5.60085  1.000 79.05985  ? 651  LEU   A N   1 
ATOM   491  C CA  . LEU   A 1 105 ? -52.59447 -6.46604  -5.28534  1.000 72.68215  ? 651  LEU   A CA  1 
ATOM   492  C C   . LEU   A 1 105 ? -53.95913 -5.98073  -5.75333  1.000 73.12037  ? 651  LEU   A C   1 
ATOM   493  O O   . LEU   A 1 105 ? -54.78113 -6.77526  -6.22288  1.000 71.71941  ? 651  LEU   A O   1 
ATOM   494  C CB  . LEU   A 1 105 ? -52.62742 -6.74930  -3.78337  1.000 63.53716  ? 651  LEU   A CB  1 
ATOM   495  C CG  . LEU   A 1 105 ? -51.45829 -7.50617  -3.15824  1.000 63.33448  ? 651  LEU   A CG  1 
ATOM   496  C CD1 . LEU   A 1 105 ? -51.67219 -7.68204  -1.66100  1.000 58.27746  ? 651  LEU   A CD1 1 
ATOM   497  C CD2 . LEU   A 1 105 ? -51.28201 -8.85068  -3.83293  1.000 57.12159  ? 651  LEU   A CD2 1 
ATOM   498  N N   . GLY   A 1 106 ? -54.21669 -4.68184  -5.64188  1.000 65.98762  ? 652  GLY   A N   1 
ATOM   499  C CA  . GLY   A 1 106 ? -55.54123 -4.15696  -5.86373  1.000 62.51308  ? 652  GLY   A CA  1 
ATOM   500  C C   . GLY   A 1 106 ? -56.41962 -4.44044  -4.66413  1.000 58.64018  ? 652  GLY   A C   1 
ATOM   501  O O   . GLY   A 1 106 ? -56.02866 -5.15416  -3.73471  1.000 56.92506  ? 652  GLY   A O   1 
ATOM   502  N N   . PRO   A 1 107 ? -57.62833 -3.89170  -4.66028  1.000 59.51028  ? 653  PRO   A N   1 
ATOM   503  C CA  . PRO   A 1 107 ? -58.49910 -4.02256  -3.49024  1.000 58.66004  ? 653  PRO   A CA  1 
ATOM   504  C C   . PRO   A 1 107 ? -59.27963 -5.32749  -3.45572  1.000 60.09532  ? 653  PRO   A C   1 
ATOM   505  O O   . PRO   A 1 107 ? -59.65726 -5.89941  -4.47893  1.000 65.37803  ? 653  PRO   A O   1 
ATOM   506  C CB  . PRO   A 1 107 ? -59.45072 -2.82736  -3.64368  1.000 58.24045  ? 653  PRO   A CB  1 
ATOM   507  C CG  . PRO   A 1 107 ? -59.56169 -2.65231  -5.12636  1.000 60.52281  ? 653  PRO   A CG  1 
ATOM   508  C CD  . PRO   A 1 107 ? -58.21996 -3.03494  -5.70232  1.000 59.46447  ? 653  PRO   A CD  1 
ATOM   509  N N   . HIS   A 1 108 ? -59.51000 -5.79767  -2.23323  1.000 56.30358  ? 654  HIS   A N   1 
ATOM   510  C CA  . HIS   A 1 108 ? -60.43993 -6.88381  -1.96564  1.000 55.00740  ? 654  HIS   A CA  1 
ATOM   511  C C   . HIS   A 1 108 ? -61.06000 -6.65124  -0.59523  1.000 53.58718  ? 654  HIS   A C   1 
ATOM   512  O O   . HIS   A 1 108 ? -60.40151 -6.13357  0.31102   1.000 53.07762  ? 654  HIS   A O   1 
ATOM   513  C CB  . HIS   A 1 108 ? -59.76189 -8.25605  -2.01460  1.000 54.94243  ? 654  HIS   A CB  1 
ATOM   514  C CG  . HIS   A 1 108 ? -60.71798 -9.39933  -1.88410  1.000 53.78512  ? 654  HIS   A CG  1 
ATOM   515  N ND1 . HIS   A 1 108 ? -61.09502 -9.91765  -0.66407  1.000 50.16147  ? 654  HIS   A ND1 1 
ATOM   516  C CD2 . HIS   A 1 108 ? -61.38787 -10.11445 -2.81801  1.000 55.07801  ? 654  HIS   A CD2 1 
ATOM   517  C CE1 . HIS   A 1 108 ? -61.95119 -10.90638 -0.84936  1.000 53.27767  ? 654  HIS   A CE1 1 
ATOM   518  N NE2 . HIS   A 1 108 ? -62.14432 -11.04793 -2.14852  1.000 55.92792  ? 654  HIS   A NE2 1 
ATOM   519  N N   . LEU   A 1 109 ? -62.33010 -7.04236  -0.45140  1.000 51.98354  ? 655  LEU   A N   1 
ATOM   520  C CA  . LEU   A 1 109 ? -63.07300 -6.76692  0.77782   1.000 53.33415  ? 655  LEU   A CA  1 
ATOM   521  C C   . LEU   A 1 109 ? -62.39552 -7.34814  2.00867   1.000 51.60088  ? 655  LEU   A C   1 
ATOM   522  O O   . LEU   A 1 109 ? -62.50786 -6.78703  3.10436   1.000 52.89605  ? 655  LEU   A O   1 
ATOM   523  C CB  . LEU   A 1 109 ? -64.49248 -7.32834  0.66562   1.000 64.60020  ? 655  LEU   A CB  1 
ATOM   524  C CG  . LEU   A 1 109 ? -65.33245 -7.33112  1.94760   1.000 70.28589  ? 655  LEU   A CG  1 
ATOM   525  C CD1 . LEU   A 1 109 ? -65.94655 -5.96705  2.18982   1.000 70.09303  ? 655  LEU   A CD1 1 
ATOM   526  C CD2 . LEU   A 1 109 ? -66.39627 -8.41217  1.90570   1.000 75.77492  ? 655  LEU   A CD2 1 
ATOM   527  N N   . ASN   A 1 110 ? -61.69576 -8.47140  1.85476   1.000 48.86661  ? 656  ASN   A N   1 
ATOM   528  C CA  . ASN   A 1 110 ? -61.14984 -9.21060  2.98589   1.000 49.27538  ? 656  ASN   A CA  1 
ATOM   529  C C   . ASN   A 1 110 ? -59.63666 -9.04639  3.11674   1.000 52.04522  ? 656  ASN   A C   1 
ATOM   530  O O   . ASN   A 1 110 ? -58.97901 -9.86217  3.76954   1.000 46.10958  ? 656  ASN   A O   1 
ATOM   531  C CB  . ASN   A 1 110 ? -61.54438 -10.68692 2.87774   1.000 46.40791  ? 656  ASN   A CB  1 
ATOM   532  C CG  . ASN   A 1 110 ? -63.05047 -10.88961 2.96895   1.000 48.80740  ? 656  ASN   A CG  1 
ATOM   533  O OD1 . ASN   A 1 110 ? -63.66023 -11.53206 2.11140   1.000 50.97788  ? 656  ASN   A OD1 1 
ATOM   534  N ND2 . ASN   A 1 110 ? -63.65551 -10.33151 4.00951   1.000 45.54330  ? 656  ASN   A ND2 1 
ATOM   535  N N   . ILE   A 1 111 ? -59.07656 -8.00834  2.50073   1.000 56.85761  ? 657  ILE   A N   1 
ATOM   536  C CA  . ILE   A 1 111 ? -57.68680 -7.61242  2.67395   1.000 51.49854  ? 657  ILE   A CA  1 
ATOM   537  C C   . ILE   A 1 111 ? -57.69123 -6.18732  3.20591   1.000 47.21266  ? 657  ILE   A C   1 
ATOM   538  O O   . ILE   A 1 111 ? -58.60875 -5.41209  2.91576   1.000 43.90933  ? 657  ILE   A O   1 
ATOM   539  C CB  . ILE   A 1 111 ? -56.90279 -7.71255  1.34596   1.000 58.75335  ? 657  ILE   A CB  1 
ATOM   540  C CG1 . ILE   A 1 111 ? -57.05868 -9.10365  0.72592   1.000 53.27309  ? 657  ILE   A CG1 1 
ATOM   541  C CG2 . ILE   A 1 111 ? -55.43298 -7.40048  1.54335   1.000 62.41244  ? 657  ILE   A CG2 1 
ATOM   542  C CD1 . ILE   A 1 111 ? -56.46024 -10.20719 1.56221   1.000 47.25177  ? 657  ILE   A CD1 1 
ATOM   543  N N   . VAL   A 1 112 ? -56.68068 -5.84791  4.01447   1.000 45.37567  ? 658  VAL   A N   1 
ATOM   544  C CA  . VAL   A 1 112 ? -56.58293 -4.48067  4.51110   1.000 47.85495  ? 658  VAL   A CA  1 
ATOM   545  C C   . VAL   A 1 112 ? -56.56718 -3.52002  3.33357   1.000 52.45046  ? 658  VAL   A C   1 
ATOM   546  O O   . VAL   A 1 112 ? -55.98328 -3.80109  2.28186   1.000 54.74407  ? 658  VAL   A O   1 
ATOM   547  C CB  . VAL   A 1 112 ? -55.34816 -4.29403  5.41110   1.000 48.37723  ? 658  VAL   A CB  1 
ATOM   548  C CG1 . VAL   A 1 112 ? -55.58423 -4.92988  6.76822   1.000 45.12180  ? 658  VAL   A CG1 1 
ATOM   549  C CG2 . VAL   A 1 112 ? -54.10872 -4.86330  4.74661   1.000 47.44858  ? 658  VAL   A CG2 1 
ATOM   550  N N   . ASN   A 1 113 ? -57.23819 -2.38872  3.50776   1.000 49.81102  ? 659  ASN   A N   1 
ATOM   551  C CA  . ASN   A 1 113 ? -57.56358 -1.47135  2.42006   1.000 61.95811  ? 659  ASN   A CA  1 
ATOM   552  C C   . ASN   A 1 113 ? -56.49556 -0.38815  2.34932   1.000 59.47548  ? 659  ASN   A C   1 
ATOM   553  O O   . ASN   A 1 113 ? -56.48938 0.53964   3.16050   1.000 55.71760  ? 659  ASN   A O   1 
ATOM   554  C CB  . ASN   A 1 113 ? -58.95186 -0.87699  2.64316   1.000 67.39995  ? 659  ASN   A CB  1 
ATOM   555  C CG  . ASN   A 1 113 ? -59.39202 0.02840   1.51706   1.000 70.01934  ? 659  ASN   A CG  1 
ATOM   556  O OD1 . ASN   A 1 113 ? -59.00530 -0.15460  0.36703   1.000 76.57958  ? 659  ASN   A OD1 1 
ATOM   557  N ND2 . ASN   A 1 113 ? -60.21190 1.01833   1.84735   1.000 61.96006  ? 659  ASN   A ND2 1 
ATOM   558  N N   . LEU   A 1 114 ? -55.59954 -0.50298  1.37035   1.000 57.17567  ? 660  LEU   A N   1 
ATOM   559  C CA  . LEU   A 1 114 ? -54.57945 0.51658   1.15983   1.000 57.12319  ? 660  LEU   A CA  1 
ATOM   560  C C   . LEU   A 1 114 ? -55.23883 1.80651   0.68691   1.000 56.97987  ? 660  LEU   A C   1 
ATOM   561  O O   . LEU   A 1 114 ? -55.94470 1.81678   -0.32708  1.000 61.72464  ? 660  LEU   A O   1 
ATOM   562  C CB  . LEU   A 1 114 ? -53.54445 0.04440   0.14343   1.000 58.71450  ? 660  LEU   A CB  1 
ATOM   563  C CG  . LEU   A 1 114 ? -52.54844 1.12818   -0.27738  1.000 64.07181  ? 660  LEU   A CG  1 
ATOM   564  C CD1 . LEU   A 1 114 ? -51.65840 1.53231   0.89140   1.000 64.54102  ? 660  LEU   A CD1 1 
ATOM   565  C CD2 . LEU   A 1 114 ? -51.72007 0.70211   -1.47598  1.000 65.88495  ? 660  LEU   A CD2 1 
ATOM   566  N N   . LEU   A 1 115 ? -55.00860 2.89496   1.42063   1.000 52.25538  ? 661  LEU   A N   1 
ATOM   567  C CA  . LEU   A 1 115 ? -55.62704 4.18261   1.13139   1.000 57.35128  ? 661  LEU   A CA  1 
ATOM   568  C C   . LEU   A 1 115 ? -54.67368 5.20493   0.53371   1.000 59.95357  ? 661  LEU   A C   1 
ATOM   569  O O   . LEU   A 1 115 ? -55.10391 6.04288   -0.26148  1.000 61.10886  ? 661  LEU   A O   1 
ATOM   570  C CB  . LEU   A 1 115 ? -56.23960 4.77176   2.40605   1.000 61.39194  ? 661  LEU   A CB  1 
ATOM   571  C CG  . LEU   A 1 115 ? -57.46495 4.09207   3.01385   1.000 63.92257  ? 661  LEU   A CG  1 
ATOM   572  C CD1 . LEU   A 1 115 ? -57.87231 4.80160   4.28285   1.000 63.01091  ? 661  LEU   A CD1 1 
ATOM   573  C CD2 . LEU   A 1 115 ? -58.59805 4.04499   2.02237   1.000 63.82762  ? 661  LEU   A CD2 1 
ATOM   574  N N   . GLY   A 1 116 ? -53.40021 5.15985   0.89551   1.000 60.80023  ? 662  GLY   A N   1 
ATOM   575  C CA  . GLY   A 1 116 ? -52.44780 6.13526   0.40760   1.000 62.61485  ? 662  GLY   A CA  1 
ATOM   576  C C   . GLY   A 1 116 ? -51.09498 5.91354   1.04516   1.000 64.84786  ? 662  GLY   A C   1 
ATOM   577  O O   . GLY   A 1 116 ? -50.87855 4.94998   1.78692   1.000 63.67597  ? 662  GLY   A O   1 
ATOM   578  N N   . ALA   A 1 117 ? -50.18263 6.83482   0.74385   1.000 64.59336  ? 663  ALA   A N   1 
ATOM   579  C CA  . ALA   A 1 117 ? -48.81568 6.70276   1.22037   1.000 61.36238  ? 663  ALA   A CA  1 
ATOM   580  C C   . ALA   A 1 117 ? -48.11173 8.04944   1.18029   1.000 66.73357  ? 663  ALA   A C   1 
ATOM   581  O O   . ALA   A 1 117 ? -48.48422 8.94404   0.41705   1.000 70.10018  ? 663  ALA   A O   1 
ATOM   582  C CB  . ALA   A 1 117 ? -48.03736 5.67493   0.39337   1.000 56.19283  ? 663  ALA   A CB  1 
ATOM   583  N N   . CYS   A 1 118 ? -47.09567 8.17626   2.02868   1.000 67.14850  ? 664  CYS   A N   1 
ATOM   584  C CA  . CYS   A 1 118 ? -46.18440 9.31270   2.03877   1.000 73.86121  ? 664  CYS   A CA  1 
ATOM   585  C C   . CYS   A 1 118 ? -44.79478 8.78669   1.70826   1.000 74.08118  ? 664  CYS   A C   1 
ATOM   586  O O   . CYS   A 1 118 ? -44.24387 7.97717   2.46065   1.000 72.36185  ? 664  CYS   A O   1 
ATOM   587  C CB  . CYS   A 1 118 ? -46.18578 10.01304  3.39863   1.000 72.84514  ? 664  CYS   A CB  1 
ATOM   588  S SG  . CYS   A 1 118 ? -47.82289 10.45749  4.02669   1.000 67.51366  ? 664  CYS   A SG  1 
ATOM   589  N N   . THR   A 1 119 ? -44.23734 9.22493   0.58317   1.000 77.20554  ? 665  THR   A N   1 
ATOM   590  C CA  . THR   A 1 119 ? -42.94068 8.72746   0.14499   1.000 79.90143  ? 665  THR   A CA  1 
ATOM   591  C C   . THR   A 1 119 ? -41.90299 9.81205   -0.09390  1.000 86.47233  ? 665  THR   A C   1 
ATOM   592  O O   . THR   A 1 119 ? -40.71597 9.55535   0.11566   1.000 90.69375  ? 665  THR   A O   1 
ATOM   593  C CB  . THR   A 1 119 ? -43.08420 7.89440   -1.14198  1.000 78.02266  ? 665  THR   A CB  1 
ATOM   594  O OG1 . THR   A 1 119 ? -43.69859 8.68402   -2.16759  1.000 78.01811  ? 665  THR   A OG1 1 
ATOM   595  C CG2 . THR   A 1 119 ? -43.92601 6.64641   -0.88908  1.000 76.10167  ? 665  THR   A CG2 1 
ATOM   596  N N   . LYS   A 1 120 ? -42.30318 11.00876  -0.51157  1.000 91.84836  ? 666  LYS   A N   1 
ATOM   597  C CA  . LYS   A 1 120 ? -41.33394 12.03716  -0.85478  1.000 100.61614 ? 666  LYS   A CA  1 
ATOM   598  C C   . LYS   A 1 120 ? -40.99386 12.90501  0.35188   1.000 103.69795 ? 666  LYS   A C   1 
ATOM   599  O O   . LYS   A 1 120 ? -41.83436 13.16753  1.21865   1.000 100.90507 ? 666  LYS   A O   1 
ATOM   600  C CB  . LYS   A 1 120 ? -41.83913 12.90596  -2.01078  1.000 104.50159 ? 666  LYS   A CB  1 
ATOM   601  C CG  . LYS   A 1 120 ? -43.29019 13.34814  -1.92469  1.000 106.97424 ? 666  LYS   A CG  1 
ATOM   602  C CD  . LYS   A 1 120 ? -43.79328 13.80433  -3.29055  1.000 112.43596 ? 666  LYS   A CD  1 
ATOM   603  C CE  . LYS   A 1 120 ? -43.58430 12.72618  -4.34689  1.000 112.04152 ? 666  LYS   A CE  1 
ATOM   604  N NZ  . LYS   A 1 120 ? -44.21645 13.07884  -5.64852  1.000 112.10565 ? 666  LYS   A NZ  1 
ATOM   605  N N   . SER   A 1 121 ? -39.72685 13.32302  0.40084   1.000 111.57990 ? 667  SER   A N   1 
ATOM   606  C CA  . SER   A 1 121 ? -39.21204 14.26552  1.39698   1.000 114.93120 ? 667  SER   A CA  1 
ATOM   607  C C   . SER   A 1 121 ? -39.50303 13.80867  2.82550   1.000 109.45819 ? 667  SER   A C   1 
ATOM   608  O O   . SER   A 1 121 ? -39.83963 14.60971  3.70003   1.000 108.44250 ? 667  SER   A O   1 
ATOM   609  C CB  . SER   A 1 121 ? -39.76039 15.67311  1.15648   1.000 121.45115 ? 667  SER   A CB  1 
ATOM   610  O OG  . SER   A 1 121 ? -41.00668 15.86091  1.80397   1.000 123.81397 ? 667  SER   A OG  1 
ATOM   611  N N   . GLY   A 1 122 ? -39.35874 12.50953  3.07426   1.000 102.40814 ? 668  GLY   A N   1 
ATOM   612  C CA  . GLY   A 1 122 ? -39.53855 11.98604  4.40786   1.000 99.14577  ? 668  GLY   A CA  1 
ATOM   613  C C   . GLY   A 1 122 ? -39.59266 10.47325  4.47703   1.000 94.61164  ? 668  GLY   A C   1 
ATOM   614  O O   . GLY   A 1 122 ? -39.54433 9.77416   3.45931   1.000 93.24504  ? 668  GLY   A O   1 
ATOM   615  N N   . PRO   A 1 123 ? -39.72011 9.94030   5.69190   1.000 93.81471  ? 669  PRO   A N   1 
ATOM   616  C CA  . PRO   A 1 123 ? -39.78193 8.48513   5.85578   1.000 91.35604  ? 669  PRO   A CA  1 
ATOM   617  C C   . PRO   A 1 123 ? -41.09998 7.92767   5.34546   1.000 85.10363  ? 669  PRO   A C   1 
ATOM   618  O O   . PRO   A 1 123 ? -42.13240 8.59850   5.35519   1.000 83.33913  ? 669  PRO   A O   1 
ATOM   619  C CB  . PRO   A 1 123 ? -39.64882 8.29708   7.36979   1.000 93.93365  ? 669  PRO   A CB  1 
ATOM   620  C CG  . PRO   A 1 123 ? -40.26574 9.53604   7.93232   1.000 95.02998  ? 669  PRO   A CG  1 
ATOM   621  C CD  . PRO   A 1 123 ? -39.91113 10.64644  6.97150   1.000 96.77861  ? 669  PRO   A CD  1 
ATOM   622  N N   . ILE   A 1 124 ? -41.05873 6.67153   4.90958   1.000 80.98353  ? 670  ILE   A N   1 
ATOM   623  C CA  . ILE   A 1 124 ? -42.20441 6.07699   4.23476   1.000 72.81770  ? 670  ILE   A CA  1 
ATOM   624  C C   . ILE   A 1 124 ? -43.34034 5.85061   5.22414   1.000 67.69928  ? 670  ILE   A C   1 
ATOM   625  O O   . ILE   A 1 124 ? -43.14890 5.26235   6.29680   1.000 71.10310  ? 670  ILE   A O   1 
ATOM   626  C CB  . ILE   A 1 124 ? -41.79304 4.77065   3.54318   1.000 75.33488  ? 670  ILE   A CB  1 
ATOM   627  C CG1 . ILE   A 1 124 ? -40.71695 5.05526   2.49378   1.000 84.93942  ? 670  ILE   A CG1 1 
ATOM   628  C CG2 . ILE   A 1 124 ? -42.99648 4.11385   2.89683   1.000 70.35314  ? 670  ILE   A CG2 1 
ATOM   629  C CD1 . ILE   A 1 124 ? -39.42915 4.29394   2.70789   1.000 90.85172  ? 670  ILE   A CD1 1 
ATOM   630  N N   . TYR   A 1 125 ? -44.53109 6.32927   4.86558   1.000 62.52669  ? 671  TYR   A N   1 
ATOM   631  C CA  . TYR   A 1 125 ? -45.76896 6.04725   5.58119   1.000 60.00623  ? 671  TYR   A CA  1 
ATOM   632  C C   . TYR   A 1 125 ? -46.68239 5.23859   4.67146   1.000 58.57531  ? 671  TYR   A C   1 
ATOM   633  O O   . TYR   A 1 125 ? -46.88794 5.61080   3.51183   1.000 61.04855  ? 671  TYR   A O   1 
ATOM   634  C CB  . TYR   A 1 125 ? -46.49218 7.33332   5.99555   1.000 61.35402  ? 671  TYR   A CB  1 
ATOM   635  C CG  . TYR   A 1 125 ? -45.79391 8.19378   7.02277   1.000 64.53346  ? 671  TYR   A CG  1 
ATOM   636  C CD1 . TYR   A 1 125 ? -44.80465 7.67667   7.84977   1.000 66.10141  ? 671  TYR   A CD1 1 
ATOM   637  C CD2 . TYR   A 1 125 ? -46.14008 9.53211   7.17194   1.000 67.49749  ? 671  TYR   A CD2 1 
ATOM   638  C CE1 . TYR   A 1 125 ? -44.17627 8.47488   8.79238   1.000 72.68481  ? 671  TYR   A CE1 1 
ATOM   639  C CE2 . TYR   A 1 125 ? -45.51858 10.33366  8.10963   1.000 71.86994  ? 671  TYR   A CE2 1 
ATOM   640  C CZ  . TYR   A 1 125 ? -44.53796 9.80310   8.91766   1.000 74.35109  ? 671  TYR   A CZ  1 
ATOM   641  O OH  . TYR   A 1 125 ? -43.92173 10.60603  9.85323   1.000 79.46063  ? 671  TYR   A OH  1 
ATOM   642  N N   . ILE   A 1 126 ? -47.23479 4.14615   5.19223   1.000 57.41000  ? 672  ILE   A N   1 
ATOM   643  C CA  . ILE   A 1 126 ? -48.23358 3.35067   4.48346   1.000 55.25807  ? 672  ILE   A CA  1 
ATOM   644  C C   . ILE   A 1 126 ? -49.55271 3.51041   5.22640   1.000 56.40790  ? 672  ILE   A C   1 
ATOM   645  O O   . ILE   A 1 126 ? -49.66934 3.10768   6.39005   1.000 56.15757  ? 672  ILE   A O   1 
ATOM   646  C CB  . ILE   A 1 126 ? -47.82146 1.87371   4.37605   1.000 54.95113  ? 672  ILE   A CB  1 
ATOM   647  C CG1 . ILE   A 1 126 ? -46.47440 1.75120   3.66575   1.000 62.04154  ? 672  ILE   A CG1 1 
ATOM   648  C CG2 . ILE   A 1 126 ? -48.85478 1.07319   3.59848   1.000 52.34449  ? 672  ILE   A CG2 1 
ATOM   649  C CD1 . ILE   A 1 126 ? -46.00953 0.32336   3.48197   1.000 65.52896  ? 672  ILE   A CD1 1 
ATOM   650  N N   . ILE   A 1 127 ? -50.54119 4.10160   4.55899   1.000 54.27112  ? 673  ILE   A N   1 
ATOM   651  C CA  . ILE   A 1 127 ? -51.81034 4.47362   5.17754   1.000 53.76495  ? 673  ILE   A CA  1 
ATOM   652  C C   . ILE   A 1 127 ? -52.85686 3.42856   4.81247   1.000 53.53414  ? 673  ILE   A C   1 
ATOM   653  O O   . ILE   A 1 127 ? -53.07364 3.13784   3.62918   1.000 52.24804  ? 673  ILE   A O   1 
ATOM   654  C CB  . ILE   A 1 127 ? -52.25476 5.87800   4.73847   1.000 53.97658  ? 673  ILE   A CB  1 
ATOM   655  C CG1 . ILE   A 1 127 ? -51.15295 6.90257   5.03245   1.000 54.42852  ? 673  ILE   A CG1 1 
ATOM   656  C CG2 . ILE   A 1 127 ? -53.54601 6.27030   5.43729   1.000 52.71127  ? 673  ILE   A CG2 1 
ATOM   657  C CD1 . ILE   A 1 127 ? -51.35858 8.23713   4.35259   1.000 58.22200  ? 673  ILE   A CD1 1 
ATOM   658  N N   . ILE   A 1 128 ? -53.51095 2.87029   5.82871   1.000 50.93610  ? 674  ILE   A N   1 
ATOM   659  C CA  . ILE   A 1 128 ? -54.52584 1.84116   5.64829   1.000 54.60468  ? 674  ILE   A CA  1 
ATOM   660  C C   . ILE   A 1 128 ? -55.73853 2.21020   6.48910   1.000 53.46002  ? 674  ILE   A C   1 
ATOM   661  O O   . ILE   A 1 128 ? -55.61404 2.83432   7.54695   1.000 50.59991  ? 674  ILE   A O   1 
ATOM   662  C CB  . ILE   A 1 128 ? -53.98566 0.43443   6.01352   1.000 60.80496  ? 674  ILE   A CB  1 
ATOM   663  C CG1 . ILE   A 1 128 ? -53.55389 -0.32407  4.75530   1.000 65.03925  ? 674  ILE   A CG1 1 
ATOM   664  C CG2 . ILE   A 1 128 ? -54.99881 -0.38411  6.80661   1.000 58.74097  ? 674  ILE   A CG2 1 
ATOM   665  C CD1 . ILE   A 1 128 ? -52.06834 -0.44723  4.61071   1.000 70.51789  ? 674  ILE   A CD1 1 
ATOM   666  N N   . GLU   A 1 129 ? -56.92064 1.84796   5.99521   1.000 56.87240  ? 675  GLU   A N   1 
ATOM   667  C CA  . GLU   A 1 129 ? -58.15204 2.14075   6.71266   1.000 60.80682  ? 675  GLU   A CA  1 
ATOM   668  C C   . GLU   A 1 129 ? -58.18543 1.40569   8.04704   1.000 57.34208  ? 675  GLU   A C   1 
ATOM   669  O O   . GLU   A 1 129 ? -57.83411 0.22632   8.13917   1.000 56.03066  ? 675  GLU   A O   1 
ATOM   670  C CB  . GLU   A 1 129 ? -59.36322 1.76183   5.86215   1.000 66.88410  ? 675  GLU   A CB  1 
ATOM   671  C CG  . GLU   A 1 129 ? -60.67643 2.28706   6.40790   1.000 70.84012  ? 675  GLU   A CG  1 
ATOM   672  C CD  . GLU   A 1 129 ? -61.82435 2.13308   5.43672   1.000 73.39743  ? 675  GLU   A CD  1 
ATOM   673  O OE1 . GLU   A 1 129 ? -61.77781 1.22065   4.58674   1.000 70.38683  ? 675  GLU   A OE1 1 
ATOM   674  O OE2 . GLU   A 1 129 ? -62.77717 2.93221   5.52405   1.000 74.59039  ? 675  GLU   A OE2 1 
ATOM   675  N N   . TYR   A 1 130 ? -58.62234 2.11476   9.08307   1.000 55.71269  ? 676  TYR   A N   1 
ATOM   676  C CA  . TYR   A 1 130 ? -58.61731 1.56333   10.42928  1.000 53.64523  ? 676  TYR   A CA  1 
ATOM   677  C C   . TYR   A 1 130 ? -59.71356 0.51848   10.58546  1.000 49.35491  ? 676  TYR   A C   1 
ATOM   678  O O   . TYR   A 1 130 ? -60.86935 0.75280   10.22323  1.000 51.53199  ? 676  TYR   A O   1 
ATOM   679  C CB  . TYR   A 1 130 ? -58.80172 2.67630   11.45680  1.000 55.43511  ? 676  TYR   A CB  1 
ATOM   680  C CG  . TYR   A 1 130 ? -58.70150 2.20660   12.88747  1.000 61.40566  ? 676  TYR   A CG  1 
ATOM   681  C CD1 . TYR   A 1 130 ? -57.46794 1.91442   13.45651  1.000 62.76972  ? 676  TYR   A CD1 1 
ATOM   682  C CD2 . TYR   A 1 130 ? -59.83789 2.05519   13.67073  1.000 64.70365  ? 676  TYR   A CD2 1 
ATOM   683  C CE1 . TYR   A 1 130 ? -57.36912 1.49125   14.76797  1.000 61.50709  ? 676  TYR   A CE1 1 
ATOM   684  C CE2 . TYR   A 1 130 ? -59.74961 1.62768   14.98114  1.000 63.95787  ? 676  TYR   A CE2 1 
ATOM   685  C CZ  . TYR   A 1 130 ? -58.51351 1.34739   15.52593  1.000 62.90923  ? 676  TYR   A CZ  1 
ATOM   686  O OH  . TYR   A 1 130 ? -58.42813 0.91856   16.83177  1.000 65.85006  ? 676  TYR   A OH  1 
ATOM   687  N N   . CYS   A 1 131 ? -59.34336 -0.63463  11.13589  1.000 49.68153  ? 677  CYS   A N   1 
ATOM   688  C CA  . CYS   A 1 131 ? -60.26820 -1.72659  11.40919  1.000 48.41238  ? 677  CYS   A CA  1 
ATOM   689  C C   . CYS   A 1 131 ? -60.70095 -1.63778  12.86704  1.000 51.47896  ? 677  CYS   A C   1 
ATOM   690  O O   . CYS   A 1 131 ? -59.87483 -1.77041  13.77653  1.000 52.66219  ? 677  CYS   A O   1 
ATOM   691  C CB  . CYS   A 1 131 ? -59.62373 -3.07282  11.09170  1.000 46.33926  ? 677  CYS   A CB  1 
ATOM   692  S SG  . CYS   A 1 131 ? -59.13689 -3.24013  9.35689   1.000 52.59191  ? 677  CYS   A SG  1 
ATOM   693  N N   . PHE   A 1 132 ? -62.00249 -1.42606  13.07297  1.000 50.44199  ? 678  PHE   A N   1 
ATOM   694  C CA  . PHE   A 1 132 ? -62.52374 -0.99366  14.36727  1.000 53.57668  ? 678  PHE   A CA  1 
ATOM   695  C C   . PHE   A 1 132 ? -62.18037 -1.96688  15.49167  1.000 56.54118  ? 678  PHE   A C   1 
ATOM   696  O O   . PHE   A 1 132 ? -61.81156 -1.54804  16.59679  1.000 52.48763  ? 678  PHE   A O   1 
ATOM   697  C CB  . PHE   A 1 132 ? -64.03892 -0.80815  14.24195  1.000 55.05531  ? 678  PHE   A CB  1 
ATOM   698  C CG  . PHE   A 1 132 ? -64.72124 -0.37485  15.50869  1.000 59.11114  ? 678  PHE   A CG  1 
ATOM   699  C CD1 . PHE   A 1 132 ? -64.81790 0.96974   15.83987  1.000 59.63413  ? 678  PHE   A CD1 1 
ATOM   700  C CD2 . PHE   A 1 132 ? -65.30419 -1.31036  16.34799  1.000 57.75663  ? 678  PHE   A CD2 1 
ATOM   701  C CE1 . PHE   A 1 132 ? -65.46276 1.36635   17.00021  1.000 67.43808  ? 678  PHE   A CE1 1 
ATOM   702  C CE2 . PHE   A 1 132 ? -65.94761 -0.91934  17.50942  1.000 64.59462  ? 678  PHE   A CE2 1 
ATOM   703  C CZ  . PHE   A 1 132 ? -66.02729 0.42264   17.83648  1.000 65.71113  ? 678  PHE   A CZ  1 
ATOM   704  N N   . TYR   A 1 133 ? -62.28410 -3.26747  15.23039  1.000 51.82564  ? 679  TYR   A N   1 
ATOM   705  C CA  . TYR   A 1 133 ? -62.19246 -4.25676  16.29699  1.000 50.61004  ? 679  TYR   A CA  1 
ATOM   706  C C   . TYR   A 1 133 ? -60.77205 -4.73813  16.57072  1.000 53.33183  ? 679  TYR   A C   1 
ATOM   707  O O   . TYR   A 1 133 ? -60.56913 -5.52039  17.50924  1.000 60.45291  ? 679  TYR   A O   1 
ATOM   708  C CB  . TYR   A 1 133 ? -63.07202 -5.46175  15.97051  1.000 48.12976  ? 679  TYR   A CB  1 
ATOM   709  C CG  . TYR   A 1 133 ? -64.55089 -5.15415  15.97989  1.000 49.94048  ? 679  TYR   A CG  1 
ATOM   710  C CD1 . TYR   A 1 133 ? -65.22142 -4.92848  17.17350  1.000 50.53395  ? 679  TYR   A CD1 1 
ATOM   711  C CD2 . TYR   A 1 133 ? -65.27645 -5.09682  14.79782  1.000 48.23501  ? 679  TYR   A CD2 1 
ATOM   712  C CE1 . TYR   A 1 133 ? -66.57150 -4.65057  17.19245  1.000 54.49113  ? 679  TYR   A CE1 1 
ATOM   713  C CE2 . TYR   A 1 133 ? -66.62790 -4.81974  14.80525  1.000 56.10235  ? 679  TYR   A CE2 1 
ATOM   714  C CZ  . TYR   A 1 133 ? -67.26880 -4.59741  16.00625  1.000 60.26759  ? 679  TYR   A CZ  1 
ATOM   715  O OH  . TYR   A 1 133 ? -68.61124 -4.31695  16.01679  1.000 69.38489  ? 679  TYR   A OH  1 
ATOM   716  N N   . GLY   A 1 134 ? -59.78921 -4.29464  15.78945  1.000 50.15566  ? 680  GLY   A N   1 
ATOM   717  C CA  . GLY   A 1 134 ? -58.43219 -4.76305  15.98157  1.000 51.34931  ? 680  GLY   A CA  1 
ATOM   718  C C   . GLY   A 1 134 ? -58.23996 -6.20431  15.52711  1.000 49.18187  ? 680  GLY   A C   1 
ATOM   719  O O   . GLY   A 1 134 ? -58.99835 -6.75072  14.72083  1.000 48.61487  ? 680  GLY   A O   1 
ATOM   720  N N   . ASP   A 1 135 ? -57.20195 -6.83156  16.07350  1.000 50.52384  ? 681  ASP   A N   1 
ATOM   721  C CA  . ASP   A 1 135 ? -56.80426 -8.16504  15.63730  1.000 55.88355  ? 681  ASP   A CA  1 
ATOM   722  C C   . ASP   A 1 135 ? -57.74919 -9.23444  16.17890  1.000 54.90749  ? 681  ASP   A C   1 
ATOM   723  O O   . ASP   A 1 135 ? -58.37871 -9.07083  17.22830  1.000 49.04025  ? 681  ASP   A O   1 
ATOM   724  C CB  . ASP   A 1 135 ? -55.36411 -8.46966  16.06291  1.000 57.68696  ? 681  ASP   A CB  1 
ATOM   725  C CG  . ASP   A 1 135 ? -55.23532 -8.73945  17.54761  1.000 65.85215  ? 681  ASP   A CG  1 
ATOM   726  O OD1 . ASP   A 1 135 ? -55.36930 -9.91277  17.94990  1.000 67.04610  ? 681  ASP   A OD1 1 
ATOM   727  O OD2 . ASP   A 1 135 ? -55.00459 -7.77878  18.31031  1.000 72.65691  ? 681  ASP   A OD2 1 
ATOM   728  N N   . LEU   A 1 136 ? -57.82649 -10.35036 15.44597  1.000 52.36053  ? 682  LEU   A N   1 
ATOM   729  C CA  . LEU   A 1 136 ? -58.83680 -11.36721 15.72202  1.000 50.14310  ? 682  LEU   A CA  1 
ATOM   730  C C   . LEU   A 1 136 ? -58.57080 -12.10743 17.02681  1.000 45.94487  ? 682  LEU   A C   1 
ATOM   731  O O   . LEU   A 1 136 ? -59.52204 -12.49050 17.71713  1.000 52.56744  ? 682  LEU   A O   1 
ATOM   732  C CB  . LEU   A 1 136 ? -58.91625 -12.35451 14.55537  1.000 52.06683  ? 682  LEU   A CB  1 
ATOM   733  C CG  . LEU   A 1 136 ? -60.09942 -13.32406 14.53059  1.000 56.19657  ? 682  LEU   A CG  1 
ATOM   734  C CD1 . LEU   A 1 136 ? -61.41208 -12.56514 14.62359  1.000 55.57081  ? 682  LEU   A CD1 1 
ATOM   735  C CD2 . LEU   A 1 136 ? -60.05507 -14.18665 13.28879  1.000 55.89136  ? 682  LEU   A CD2 1 
ATOM   736  N N   . VAL   A 1 137 ? -57.30153 -12.31633 17.38153  1.000 42.81423  ? 683  VAL   A N   1 
ATOM   737  C CA  . VAL   A 1 137 ? -56.98361 -13.03399 18.61524  1.000 50.70093  ? 683  VAL   A CA  1 
ATOM   738  C C   . VAL   A 1 137 ? -57.58166 -12.31960 19.81666  1.000 55.51238  ? 683  VAL   A C   1 
ATOM   739  O O   . VAL   A 1 137 ? -58.31241 -12.91721 20.61485  1.000 54.42926  ? 683  VAL   A O   1 
ATOM   740  C CB  . VAL   A 1 137 ? -55.46336 -13.19414 18.77531  1.000 56.35080  ? 683  VAL   A CB  1 
ATOM   741  C CG1 . VAL   A 1 137 ? -55.13931 -13.90195 20.07721  1.000 60.44855  ? 683  VAL   A CG1 1 
ATOM   742  C CG2 . VAL   A 1 137 ? -54.88146 -13.96255 17.61911  1.000 59.84185  ? 683  VAL   A CG2 1 
ATOM   743  N N   . ASN   A 1 138 ? -57.28510 -11.02494 19.95683  1.000 55.52445  ? 684  ASN   A N   1 
ATOM   744  C CA  . ASN   A 1 138 ? -57.79665 -10.26535 21.09289  1.000 57.49612  ? 684  ASN   A CA  1 
ATOM   745  C C   . ASN   A 1 138 ? -59.31415 -10.14698 21.04099  1.000 53.72956  ? 684  ASN   A C   1 
ATOM   746  O O   . ASN   A 1 138 ? -59.97831 -10.15262 22.08507  1.000 54.23574  ? 684  ASN   A O   1 
ATOM   747  C CB  . ASN   A 1 138 ? -57.14570 -8.87960  21.13785  1.000 58.15677  ? 684  ASN   A CB  1 
ATOM   748  C CG  . ASN   A 1 138 ? -55.73630 -8.91399  21.69432  1.000 66.01545  ? 684  ASN   A CG  1 
ATOM   749  O OD1 . ASN   A 1 138 ? -55.48198 -9.50732  22.74203  1.000 75.11600  ? 684  ASN   A OD1 1 
ATOM   750  N ND2 . ASN   A 1 138 ? -54.80862 -8.28700  20.98564  1.000 68.00365  ? 684  ASN   A ND2 1 
ATOM   751  N N   . TYR   A 1 139 ? -59.88257 -10.05192 19.83544  1.000 46.43321  ? 685  TYR   A N   1 
ATOM   752  C CA  . TYR   A 1 139 ? -61.33711 -10.01531 19.70741  1.000 47.66499  ? 685  TYR   A CA  1 
ATOM   753  C C   . TYR   A 1 139 ? -61.96354 -11.30705 20.21520  1.000 51.26007  ? 685  TYR   A C   1 
ATOM   754  O O   . TYR   A 1 139 ? -62.95097 -11.28437 20.95795  1.000 55.57113  ? 685  TYR   A O   1 
ATOM   755  C CB  . TYR   A 1 139 ? -61.73743 -9.76114  18.25132  1.000 41.93443  ? 685  TYR   A CB  1 
ATOM   756  C CG  . TYR   A 1 139 ? -63.23569 -9.69698  18.03409  1.000 48.04491  ? 685  TYR   A CG  1 
ATOM   757  C CD1 . TYR   A 1 139 ? -63.94144 -8.52545  18.27854  1.000 52.10208  ? 685  TYR   A CD1 1 
ATOM   758  C CD2 . TYR   A 1 139 ? -63.94745 -10.80678 17.58592  1.000 52.26011  ? 685  TYR   A CD2 1 
ATOM   759  C CE1 . TYR   A 1 139 ? -65.30960 -8.45834  18.08374  1.000 57.01654  ? 685  TYR   A CE1 1 
ATOM   760  C CE2 . TYR   A 1 139 ? -65.31762 -10.74726 17.39095  1.000 57.50750  ? 685  TYR   A CE2 1 
ATOM   761  C CZ  . TYR   A 1 139 ? -65.98999 -9.57176  17.64020  1.000 62.20692  ? 685  TYR   A CZ  1 
ATOM   762  O OH  . TYR   A 1 139 ? -67.35396 -9.50640  17.44500  1.000 77.36888  ? 685  TYR   A OH  1 
ATOM   763  N N   . LEU   A 1 140 ? -61.40095 -12.44716 19.81571  1.000 48.97390  ? 686  LEU   A N   1 
ATOM   764  C CA  . LEU   A 1 140 ? -61.91326 -13.73293 20.27694  1.000 50.12816  ? 686  LEU   A CA  1 
ATOM   765  C C   . LEU   A 1 140 ? -61.77696 -13.87415 21.78732  1.000 54.02744  ? 686  LEU   A C   1 
ATOM   766  O O   . LEU   A 1 140 ? -62.69992 -14.35202 22.45882  1.000 58.21076  ? 686  LEU   A O   1 
ATOM   767  C CB  . LEU   A 1 140 ? -61.18603 -14.87308 19.56019  1.000 52.14542  ? 686  LEU   A CB  1 
ATOM   768  C CG  . LEU   A 1 140 ? -61.47167 -15.01689 18.06256  1.000 50.72298  ? 686  LEU   A CG  1 
ATOM   769  C CD1 . LEU   A 1 140 ? -60.56018 -16.05687 17.41840  1.000 50.78221  ? 686  LEU   A CD1 1 
ATOM   770  C CD2 . LEU   A 1 140 ? -62.93459 -15.36521 17.83227  1.000 50.35545  ? 686  LEU   A CD2 1 
ATOM   771  N N   . HIS   A 1 141 ? -60.63446 -13.45713 22.33970  1.000 49.30622  ? 687  HIS   A N   1 
ATOM   772  C CA  . HIS   A 1 141 ? -60.44657 -13.50259 23.78816  1.000 55.00674  ? 687  HIS   A CA  1 
ATOM   773  C C   . HIS   A 1 141 ? -61.48999 -12.66196 24.51287  1.000 55.49640  ? 687  HIS   A C   1 
ATOM   774  O O   . HIS   A 1 141 ? -62.07749 -13.10561 25.50797  1.000 54.90634  ? 687  HIS   A O   1 
ATOM   775  C CB  . HIS   A 1 141 ? -59.04060 -13.02164 24.15303  1.000 55.45288  ? 687  HIS   A CB  1 
ATOM   776  C CG  . HIS   A 1 141 ? -57.94810 -13.95936 23.74399  1.000 61.37769  ? 687  HIS   A CG  1 
ATOM   777  N ND1 . HIS   A 1 141 ? -56.61834 -13.59868 23.77231  1.000 64.75055  ? 687  HIS   A ND1 1 
ATOM   778  C CD2 . HIS   A 1 141 ? -57.98195 -15.23998 23.30417  1.000 62.33960  ? 687  HIS   A CD2 1 
ATOM   779  C CE1 . HIS   A 1 141 ? -55.87967 -14.61294 23.36083  1.000 64.19909  ? 687  HIS   A CE1 1 
ATOM   780  N NE2 . HIS   A 1 141 ? -56.68260 -15.62010 23.06699  1.000 62.26931  ? 687  HIS   A NE2 1 
ATOM   781  N N   . LYS   A 1 142 ? -61.72871 -11.44259 24.02661  1.000 53.41927  ? 688  LYS   A N   1 
ATOM   782  C CA  . LYS   A 1 142 ? -62.68636 -10.54232 24.65576  1.000 57.63803  ? 688  LYS   A CA  1 
ATOM   783  C C   . LYS   A 1 142 ? -64.11234 -11.07974 24.61657  1.000 55.89280  ? 688  LYS   A C   1 
ATOM   784  O O   . LYS   A 1 142 ? -64.91221 -10.73368 25.48940  1.000 55.83658  ? 688  LYS   A O   1 
ATOM   785  C CB  . LYS   A 1 142 ? -62.61743 -9.17125  23.97755  1.000 62.64612  ? 688  LYS   A CB  1 
ATOM   786  C CG  . LYS   A 1 142 ? -63.55347 -8.11251  24.54726  1.000 68.95437  ? 688  LYS   A CG  1 
ATOM   787  C CD  . LYS   A 1 142 ? -63.35872 -6.77803  23.84772  1.000 70.69487  ? 688  LYS   A CD  1 
ATOM   788  C CE  . LYS   A 1 142 ? -64.42483 -5.76953  24.23425  1.000 76.31296  ? 688  LYS   A CE  1 
ATOM   789  N NZ  . LYS   A 1 142 ? -64.27020 -4.50193  23.46578  1.000 76.64109  ? 688  LYS   A NZ  1 
ATOM   790  N N   . ASN   A 1 143 ? -64.44775 -11.92266 23.64056  1.000 55.22235  ? 689  ASN   A N   1 
ATOM   791  C CA  . ASN   A 1 143 ? -65.79974 -12.44906 23.48544  1.000 57.67158  ? 689  ASN   A CA  1 
ATOM   792  C C   . ASN   A 1 143 ? -65.91077 -13.92272 23.86186  1.000 60.72504  ? 689  ASN   A C   1 
ATOM   793  O O   . ASN   A 1 143 ? -66.97645 -14.51825 23.67066  1.000 61.54860  ? 689  ASN   A O   1 
ATOM   794  C CB  . ASN   A 1 143 ? -66.29032 -12.24736 22.04577  1.000 54.59058  ? 689  ASN   A CB  1 
ATOM   795  C CG  . ASN   A 1 143 ? -66.55764 -10.79174 21.71355  1.000 54.00946  ? 689  ASN   A CG  1 
ATOM   796  O OD1 . ASN   A 1 143 ? -67.63074 -10.26117 22.01481  1.000 59.58878  ? 689  ASN   A OD1 1 
ATOM   797  N ND2 . ASN   A 1 143 ? -65.59508 -10.14719 21.06606  1.000 50.19441  ? 689  ASN   A ND2 1 
ATOM   798  N N   . ARG   A 1 144 ? -64.84009 -14.52780 24.38609  1.000 59.37545  ? 690  ARG   A N   1 
ATOM   799  C CA  . ARG   A 1 144 ? -64.87592 -15.95565 24.69450  1.000 59.93176  ? 690  ARG   A CA  1 
ATOM   800  C C   . ARG   A 1 144 ? -65.88757 -16.27344 25.79267  1.000 64.04835  ? 690  ARG   A C   1 
ATOM   801  O O   . ARG   A 1 144 ? -66.61588 -17.26835 25.70293  1.000 64.87684  ? 690  ARG   A O   1 
ATOM   802  C CB  . ARG   A 1 144 ? -63.48540 -16.44774 25.10123  1.000 62.65498  ? 690  ARG   A CB  1 
ATOM   803  C CG  . ARG   A 1 144 ? -63.45071 -17.93283 25.40791  1.000 67.73416  ? 690  ARG   A CG  1 
ATOM   804  C CD  . ARG   A 1 144 ? -62.05425 -18.44888 25.71909  1.000 70.22499  ? 690  ARG   A CD  1 
ATOM   805  N NE  . ARG   A 1 144 ? -62.02310 -19.90712 25.64460  1.000 79.06990  ? 690  ARG   A NE  1 
ATOM   806  C CZ  . ARG   A 1 144 ? -61.08947 -20.66966 26.20428  1.000 87.96618  ? 690  ARG   A CZ  1 
ATOM   807  N NH1 . ARG   A 1 144 ? -60.10220 -20.11759 26.89704  1.000 90.42704  ? 690  ARG   A NH1 1 
ATOM   808  N NH2 . ARG   A 1 144 ? -61.14735 -21.98796 26.07718  1.000 90.21197  ? 690  ARG   A NH2 1 
ATOM   809  N N   . ASP   A 1 145 ? -65.95452 -15.44455 26.83657  1.000 66.93629  ? 691  ASP   A N   1 
ATOM   810  C CA  . ASP   A 1 145 ? -66.75372 -15.81351 28.00284  1.000 69.76623  ? 691  ASP   A CA  1 
ATOM   811  C C   . ASP   A 1 145 ? -68.24787 -15.66419 27.74993  1.000 66.09650  ? 691  ASP   A C   1 
ATOM   812  O O   . ASP   A 1 145 ? -69.04479 -16.41727 28.31737  1.000 62.54233  ? 691  ASP   A O   1 
ATOM   813  C CB  . ASP   A 1 145 ? -66.33846 -14.98254 29.21367  1.000 72.84019  ? 691  ASP   A CB  1 
ATOM   814  C CG  . ASP   A 1 145 ? -64.97612 -15.36822 29.73434  1.000 74.89167  ? 691  ASP   A CG  1 
ATOM   815  O OD1 . ASP   A 1 145 ? -64.43631 -16.38573 29.25614  1.000 73.74283  ? 691  ASP   A OD1 1 
ATOM   816  O OD2 . ASP   A 1 145 ? -64.44614 -14.65725 30.60985  1.000 77.90009  ? 691  ASP   A OD2 1 
ATOM   817  N N   . SER   A 1 146 ? -68.64952 -14.70712 26.91961  1.000 68.59193  ? 692  SER   A N   1 
ATOM   818  C CA  . SER   A 1 146 ? -70.05465 -14.50460 26.59770  1.000 78.89277  ? 692  SER   A CA  1 
ATOM   819  C C   . SER   A 1 146 ? -70.49767 -15.28881 25.36625  1.000 81.22448  ? 692  SER   A C   1 
ATOM   820  O O   . SER   A 1 146 ? -71.57249 -15.01239 24.82431  1.000 81.19707  ? 692  SER   A O   1 
ATOM   821  C CB  . SER   A 1 146 ? -70.33950 -13.01374 26.40034  1.000 79.92943  ? 692  SER   A CB  1 
ATOM   822  O OG  . SER   A 1 146 ? -69.41059 -12.42621 25.50609  1.000 80.21539  ? 692  SER   A OG  1 
ATOM   823  N N   . PHE   A 1 147 ? -69.70591 -16.26288 24.92141  1.000 82.59036  ? 693  PHE   A N   1 
ATOM   824  C CA  . PHE   A 1 147 ? -70.03609 -16.99951 23.70720  1.000 86.61893  ? 693  PHE   A CA  1 
ATOM   825  C C   . PHE   A 1 147 ? -71.31049 -17.81267 23.89558  1.000 93.98069  ? 693  PHE   A C   1 
ATOM   826  O O   . PHE   A 1 147 ? -71.46299 -18.53381 24.88626  1.000 95.46962  ? 693  PHE   A O   1 
ATOM   827  C CB  . PHE   A 1 147 ? -68.88014 -17.92087 23.31229  1.000 84.72722  ? 693  PHE   A CB  1 
ATOM   828  C CG  . PHE   A 1 147 ? -69.05079 -18.56398 21.96230  1.000 78.68409  ? 693  PHE   A CG  1 
ATOM   829  C CD1 . PHE   A 1 147 ? -68.67489 -17.89349 20.81248  1.000 77.25332  ? 693  PHE   A CD1 1 
ATOM   830  C CD2 . PHE   A 1 147 ? -69.58606 -19.83831 21.84310  1.000 79.57486  ? 693  PHE   A CD2 1 
ATOM   831  C CE1 . PHE   A 1 147 ? -68.82903 -18.47879 19.56758  1.000 77.72736  ? 693  PHE   A CE1 1 
ATOM   832  C CE2 . PHE   A 1 147 ? -69.74265 -20.42764 20.60077  1.000 79.11038  ? 693  PHE   A CE2 1 
ATOM   833  C CZ  . PHE   A 1 147 ? -69.36403 -19.74854 19.46476  1.000 77.23516  ? 693  PHE   A CZ  1 
ATOM   834  N N   . LEU   A 1 148 ? -72.22453 -17.69491 22.93624  1.000 97.39846  ? 694  LEU   A N   1 
ATOM   835  C CA  . LEU   A 1 148 ? -73.47815 -18.43810 22.97733  1.000 102.58533 ? 694  LEU   A CA  1 
ATOM   836  C C   . LEU   A 1 148 ? -73.27127 -19.87416 22.50673  1.000 105.70423 ? 694  LEU   A C   1 
ATOM   837  O O   . LEU   A 1 148 ? -73.24448 -20.14408 21.30550  1.000 103.96700 ? 694  LEU   A O   1 
ATOM   838  C CB  . LEU   A 1 148 ? -74.54378 -17.75299 22.11851  1.000 100.22733 ? 694  LEU   A CB  1 
ATOM   839  N N   . GLY   A 1 171 ? -73.60474 -10.55198 21.33383  1.000 102.68724 ? 789  GLY   A N   1 
ATOM   840  C CA  . GLY   A 1 171 ? -72.65095 -11.59783 21.65578  1.000 103.02486 ? 789  GLY   A CA  1 
ATOM   841  C C   . GLY   A 1 171 ? -71.90548 -12.12630 20.44565  1.000 102.50929 ? 789  GLY   A C   1 
ATOM   842  O O   . GLY   A 1 171 ? -71.93120 -11.52181 19.37642  1.000 106.86279 ? 789  GLY   A O   1 
ATOM   843  N N   . LEU   A 1 172 ? -71.22949 -13.25669 20.63013  1.000 89.73729  ? 790  LEU   A N   1 
ATOM   844  C CA  . LEU   A 1 172 ? -70.53814 -13.96625 19.56351  1.000 78.21945  ? 790  LEU   A CA  1 
ATOM   845  C C   . LEU   A 1 172 ? -71.19053 -15.33101 19.40947  1.000 73.96759  ? 790  LEU   A C   1 
ATOM   846  O O   . LEU   A 1 172 ? -71.41339 -16.02761 20.40398  1.000 75.86016  ? 790  LEU   A O   1 
ATOM   847  C CB  . LEU   A 1 172 ? -69.04130 -14.11959 19.87305  1.000 77.14455  ? 790  LEU   A CB  1 
ATOM   848  C CG  . LEU   A 1 172 ? -67.96966 -13.46128 18.99262  1.000 70.21495  ? 790  LEU   A CG  1 
ATOM   849  C CD1 . LEU   A 1 172 ? -66.67245 -14.26816 19.05402  1.000 65.80171  ? 790  LEU   A CD1 1 
ATOM   850  C CD2 . LEU   A 1 172 ? -68.43058 -13.30089 17.56023  1.000 69.38335  ? 790  LEU   A CD2 1 
ATOM   851  N N   . THR   A 1 173 ? -71.50049 -15.70991 18.17342  1.000 67.63698  ? 791  THR   A N   1 
ATOM   852  C CA  . THR   A 1 173 ? -72.19722 -16.95743 17.89795  1.000 68.21611  ? 791  THR   A CA  1 
ATOM   853  C C   . THR   A 1 173 ? -71.34078 -17.85914 17.01539  1.000 63.54147  ? 791  THR   A C   1 
ATOM   854  O O   . THR   A 1 173 ? -70.36985 -17.41776 16.39534  1.000 63.10155  ? 791  THR   A O   1 
ATOM   855  C CB  . THR   A 1 173 ? -73.55078 -16.70503 17.21561  1.000 75.60987  ? 791  THR   A CB  1 
ATOM   856  O OG1 . THR   A 1 173 ? -73.33573 -16.32584 15.85238  1.000 79.23098  ? 791  THR   A OG1 1 
ATOM   857  C CG2 . THR   A 1 173 ? -74.30837 -15.58987 17.92304  1.000 74.78077  ? 791  THR   A CG2 1 
ATOM   858  N N   . LEU   A 1 174 ? -71.71320 -19.14255 16.97172  1.000 58.36636  ? 792  LEU   A N   1 
ATOM   859  C CA  . LEU   A 1 174 ? -71.05722 -20.08619 16.07005  1.000 57.60214  ? 792  LEU   A CA  1 
ATOM   860  C C   . LEU   A 1 174 ? -71.10594 -19.59067 14.63159  1.000 53.61226  ? 792  LEU   A C   1 
ATOM   861  O O   . LEU   A 1 174 ? -70.16540 -19.80300 13.85806  1.000 54.35760  ? 792  LEU   A O   1 
ATOM   862  C CB  . LEU   A 1 174 ? -71.72157 -21.45988 16.18063  1.000 68.47689  ? 792  LEU   A CB  1 
ATOM   863  C CG  . LEU   A 1 174 ? -71.31933 -22.51723 15.14489  1.000 75.70548  ? 792  LEU   A CG  1 
ATOM   864  C CD1 . LEU   A 1 174 ? -69.89880 -22.99362 15.38583  1.000 77.03612  ? 792  LEU   A CD1 1 
ATOM   865  C CD2 . LEU   A 1 174 ? -72.29381 -23.68710 15.14459  1.000 80.32993  ? 792  LEU   A CD2 1 
ATOM   866  N N   . LEU   A 1 175 ? -72.20091 -18.92184 14.25896  1.000 54.35268  ? 793  LEU   A N   1 
ATOM   867  C CA  . LEU   A 1 175 ? -72.33258 -18.38858 12.90690  1.000 53.39104  ? 793  LEU   A CA  1 
ATOM   868  C C   . LEU   A 1 175 ? -71.28044 -17.32544 12.62384  1.000 51.09425  ? 793  LEU   A C   1 
ATOM   869  O O   . LEU   A 1 175 ? -70.72161 -17.27401 11.52232  1.000 51.97222  ? 793  LEU   A O   1 
ATOM   870  C CB  . LEU   A 1 175 ? -73.73938 -17.82369 12.70651  1.000 54.06878  ? 793  LEU   A CB  1 
ATOM   871  C CG  . LEU   A 1 175 ? -74.86706 -18.86201 12.80394  1.000 58.74556  ? 793  LEU   A CG  1 
ATOM   872  C CD1 . LEU   A 1 175 ? -76.23093 -18.25870 12.48665  1.000 63.71487  ? 793  LEU   A CD1 1 
ATOM   873  C CD2 . LEU   A 1 175 ? -74.57027 -20.03867 11.88888  1.000 53.37109  ? 793  LEU   A CD2 1 
ATOM   874  N N   . ASP   A 1 176 ? -71.00071 -16.46509 13.60434  1.000 47.50347  ? 794  ASP   A N   1 
ATOM   875  C CA  . ASP   A 1 176 ? -69.94374 -15.47188 13.43923  1.000 52.44274  ? 794  ASP   A CA  1 
ATOM   876  C C   . ASP   A 1 176 ? -68.60180 -16.13623 13.16640  1.000 49.17458  ? 794  ASP   A C   1 
ATOM   877  O O   . ASP   A 1 176 ? -67.82998 -15.67282 12.31720  1.000 46.49543  ? 794  ASP   A O   1 
ATOM   878  C CB  . ASP   A 1 176 ? -69.85501 -14.59291 14.68343  1.000 59.58596  ? 794  ASP   A CB  1 
ATOM   879  C CG  . ASP   A 1 176 ? -71.06198 -13.69291 14.85061  1.000 67.13958  ? 794  ASP   A CG  1 
ATOM   880  O OD1 . ASP   A 1 176 ? -71.45957 -13.04020 13.86472  1.000 68.91092  ? 794  ASP   A OD1 1 
ATOM   881  O OD2 . ASP   A 1 176 ? -71.61181 -13.63511 15.97196  1.000 74.26133  ? 794  ASP   A OD2 1 
ATOM   882  N N   . LEU   A 1 177 ? -68.30688 -17.22502 13.88205  1.000 48.55433  ? 795  LEU   A N   1 
ATOM   883  C CA  . LEU   A 1 177 ? -67.06230 -17.95444 13.65144  1.000 47.20961  ? 795  LEU   A CA  1 
ATOM   884  C C   . LEU   A 1 177 ? -67.03360 -18.55826 12.25500  1.000 44.66177  ? 795  LEU   A C   1 
ATOM   885  O O   . LEU   A 1 177 ? -66.00171 -18.52846 11.57546  1.000 47.29731  ? 795  LEU   A O   1 
ATOM   886  C CB  . LEU   A 1 177 ? -66.88320 -19.04809 14.70960  1.000 49.40432  ? 795  LEU   A CB  1 
ATOM   887  C CG  . LEU   A 1 177 ? -66.97791 -18.65127 16.18658  1.000 53.73044  ? 795  LEU   A CG  1 
ATOM   888  C CD1 . LEU   A 1 177 ? -66.45078 -19.76100 17.10102  1.000 58.90369  ? 795  LEU   A CD1 1 
ATOM   889  C CD2 . LEU   A 1 177 ? -66.25668 -17.33834 16.44923  1.000 51.62757  ? 795  LEU   A CD2 1 
ATOM   890  N N   . LEU   A 1 178 ? -68.16118 -19.11387 11.81335  1.000 44.96603  ? 796  LEU   A N   1 
ATOM   891  C CA  . LEU   A 1 178 ? -68.25265 -19.62654 10.45209  1.000 48.23383  ? 796  LEU   A CA  1 
ATOM   892  C C   . LEU   A 1 178 ? -68.04177 -18.51595 9.42737   1.000 47.68889  ? 796  LEU   A C   1 
ATOM   893  O O   . LEU   A 1 178 ? -67.37809 -18.72263 8.40268   1.000 43.49547  ? 796  LEU   A O   1 
ATOM   894  C CB  . LEU   A 1 178 ? -69.60576 -20.30187 10.24359  1.000 49.64716  ? 796  LEU   A CB  1 
ATOM   895  C CG  . LEU   A 1 178 ? -69.75052 -21.67763 10.89461  1.000 53.69013  ? 796  LEU   A CG  1 
ATOM   896  C CD1 . LEU   A 1 178 ? -71.16016 -22.21818 10.72604  1.000 54.10980  ? 796  LEU   A CD1 1 
ATOM   897  C CD2 . LEU   A 1 178 ? -68.73252 -22.63583 10.30148  1.000 56.05080  ? 796  LEU   A CD2 1 
ATOM   898  N N   . SER   A 1 179 ? -68.58222 -17.32285 9.69568   1.000 45.77155  ? 797  SER   A N   1 
ATOM   899  C CA  . SER   A 1 179 ? -68.41252 -16.20241 8.77213   1.000 43.17873  ? 797  SER   A CA  1 
ATOM   900  C C   . SER   A 1 179 ? -66.94816 -15.78481 8.67563   1.000 46.27480  ? 797  SER   A C   1 
ATOM   901  O O   . SER   A 1 179 ? -66.41711 -15.58410 7.57573   1.000 46.95450  ? 797  SER   A O   1 
ATOM   902  C CB  . SER   A 1 179 ? -69.28404 -15.02424 9.21195   1.000 41.69083  ? 797  SER   A CB  1 
ATOM   903  O OG  . SER   A 1 179 ? -69.06529 -13.89376 8.38951   1.000 50.07483  ? 797  SER   A OG  1 
ATOM   904  N N   . PHE   A 1 180 ? -66.27779 -15.64648 9.82317   1.000 46.50284  ? 798  PHE   A N   1 
ATOM   905  C CA  . PHE   A 1 180 ? -64.84556 -15.35676 9.81752   1.000 46.67171  ? 798  PHE   A CA  1 
ATOM   906  C C   . PHE   A 1 180 ? -64.09465 -16.39228 8.99576   1.000 46.46902  ? 798  PHE   A C   1 
ATOM   907  O O   . PHE   A 1 180 ? -63.22346 -16.05727 8.18577   1.000 44.34003  ? 798  PHE   A O   1 
ATOM   908  C CB  . PHE   A 1 180 ? -64.29361 -15.33651 11.24516  1.000 44.45852  ? 798  PHE   A CB  1 
ATOM   909  C CG  . PHE   A 1 180 ? -64.92952 -14.31613 12.14087  1.000 46.46582  ? 798  PHE   A CG  1 
ATOM   910  C CD1 . PHE   A 1 180 ? -65.61469 -13.22618 11.62277  1.000 45.69748  ? 798  PHE   A CD1 1 
ATOM   911  C CD2 . PHE   A 1 180 ? -64.82987 -14.45118 13.51566  1.000 47.77305  ? 798  PHE   A CD2 1 
ATOM   912  C CE1 . PHE   A 1 180 ? -66.19598 -12.29172 12.46535  1.000 43.62231  ? 798  PHE   A CE1 1 
ATOM   913  C CE2 . PHE   A 1 180 ? -65.40108 -13.52661 14.36452  1.000 48.75553  ? 798  PHE   A CE2 1 
ATOM   914  C CZ  . PHE   A 1 180 ? -66.08711 -12.44365 13.84156  1.000 46.83239  ? 798  PHE   A CZ  1 
ATOM   915  N N   . THR   A 1 181 ? -64.43032 -17.66532 9.20387   1.000 45.48627  ? 799  THR   A N   1 
ATOM   916  C CA  . THR   A 1 181 ? -63.79653 -18.75526 8.47202   1.000 46.54556  ? 799  THR   A CA  1 
ATOM   917  C C   . THR   A 1 181 ? -63.98091 -18.58930 6.97010   1.000 47.22979  ? 799  THR   A C   1 
ATOM   918  O O   . THR   A 1 181 ? -63.02413 -18.70701 6.19339   1.000 44.78501  ? 799  THR   A O   1 
ATOM   919  C CB  . THR   A 1 181 ? -64.38735 -20.08587 8.94319   1.000 49.48365  ? 799  THR   A CB  1 
ATOM   920  O OG1 . THR   A 1 181 ? -64.11305 -20.26469 10.33900  1.000 48.09373  ? 799  THR   A OG1 1 
ATOM   921  C CG2 . THR   A 1 181 ? -63.81415 -21.23974 8.16018   1.000 53.12165  ? 799  THR   A CG2 1 
ATOM   922  N N   . TYR   A 1 182 ? -65.21396 -18.31171 6.54668   1.000 44.89191  ? 800  TYR   A N   1 
ATOM   923  C CA  . TYR   A 1 182 ? -65.49820 -18.11294 5.12993   1.000 46.03819  ? 800  TYR   A CA  1 
ATOM   924  C C   . TYR   A 1 182 ? -64.75056 -16.90355 4.57444   1.000 47.06554  ? 800  TYR   A C   1 
ATOM   925  O O   . TYR   A 1 182 ? -64.14700 -16.97475 3.49652   1.000 49.92132  ? 800  TYR   A O   1 
ATOM   926  C CB  . TYR   A 1 182 ? -67.01055 -17.96255 4.93852   1.000 45.21517  ? 800  TYR   A CB  1 
ATOM   927  C CG  . TYR   A 1 182 ? -67.44910 -17.50155 3.56924   1.000 47.45537  ? 800  TYR   A CG  1 
ATOM   928  C CD1 . TYR   A 1 182 ? -67.62392 -18.40634 2.53336   1.000 49.59929  ? 800  TYR   A CD1 1 
ATOM   929  C CD2 . TYR   A 1 182 ? -67.71023 -16.16004 3.32176   1.000 49.15120  ? 800  TYR   A CD2 1 
ATOM   930  C CE1 . TYR   A 1 182 ? -68.03476 -17.98731 1.28193   1.000 56.21441  ? 800  TYR   A CE1 1 
ATOM   931  C CE2 . TYR   A 1 182 ? -68.11943 -15.72979 2.07842   1.000 50.45912  ? 800  TYR   A CE2 1 
ATOM   932  C CZ  . TYR   A 1 182 ? -68.28064 -16.64641 1.06360   1.000 53.51192  ? 800  TYR   A CZ  1 
ATOM   933  O OH  . TYR   A 1 182 ? -68.69988 -16.20597 -0.17647  1.000 57.53889  ? 800  TYR   A OH  1 
ATOM   934  N N   . GLN   A 1 183 ? -64.77454 -15.78302 5.30467   1.000 46.53801  ? 801  GLN   A N   1 
ATOM   935  C CA  . GLN   A 1 183 ? -64.16934 -14.55016 4.80358   1.000 47.48245  ? 801  GLN   A CA  1 
ATOM   936  C C   . GLN   A 1 183 ? -62.66228 -14.68678 4.64418   1.000 43.06109  ? 801  GLN   A C   1 
ATOM   937  O O   . GLN   A 1 183 ? -62.08849 -14.20998 3.65761   1.000 43.61131  ? 801  GLN   A O   1 
ATOM   938  C CB  . GLN   A 1 183 ? -64.48754 -13.38401 5.73748   1.000 50.18667  ? 801  GLN   A CB  1 
ATOM   939  C CG  . GLN   A 1 183 ? -65.91304 -12.88673 5.63941   1.000 49.54306  ? 801  GLN   A CG  1 
ATOM   940  C CD  . GLN   A 1 183 ? -66.19964 -11.75215 6.59676   1.000 48.88015  ? 801  GLN   A CD  1 
ATOM   941  O OE1 . GLN   A 1 183 ? -65.72368 -10.63161 6.40869   1.000 50.67938  ? 801  GLN   A OE1 1 
ATOM   942  N NE2 . GLN   A 1 183 ? -66.98252 -12.03481 7.62869   1.000 47.06432  ? 801  GLN   A NE2 1 
ATOM   943  N N   . VAL   A 1 184 ? -61.99811 -15.30405 5.62103   1.000 42.25951  ? 802  VAL   A N   1 
ATOM   944  C CA  . VAL   A 1 184 ? -60.55783 -15.52546 5.51231   1.000 40.12431  ? 802  VAL   A CA  1 
ATOM   945  C C   . VAL   A 1 184 ? -60.23915 -16.31437 4.25097   1.000 43.26165  ? 802  VAL   A C   1 
ATOM   946  O O   . VAL   A 1 184 ? -59.33743 -15.95926 3.48221   1.000 47.25346  ? 802  VAL   A O   1 
ATOM   947  C CB  . VAL   A 1 184 ? -60.03001 -16.24158 6.76542   1.000 45.10576  ? 802  VAL   A CB  1 
ATOM   948  C CG1 . VAL   A 1 184 ? -58.61719 -16.71471 6.53079   1.000 40.90017  ? 802  VAL   A CG1 1 
ATOM   949  C CG2 . VAL   A 1 184 ? -60.08817 -15.31039 7.97140   1.000 44.53869  ? 802  VAL   A CG2 1 
ATOM   950  N N   . ALA   A 1 185 ? -61.01194 -17.37406 3.99966   1.000 41.86864  ? 803  ALA   A N   1 
ATOM   951  C CA  . ALA   A 1 185 ? -60.79741 -18.19352 2.81033   1.000 44.54588  ? 803  ALA   A CA  1 
ATOM   952  C C   . ALA   A 1 185 ? -60.98134 -17.38412 1.53244   1.000 49.93883  ? 803  ALA   A C   1 
ATOM   953  O O   . ALA   A 1 185 ? -60.22744 -17.55558 0.56610   1.000 52.69081  ? 803  ALA   A O   1 
ATOM   954  C CB  . ALA   A 1 185 ? -61.74350 -19.39620 2.82648   1.000 45.19092  ? 803  ALA   A CB  1 
ATOM   955  N N   . ARG   A 1 186 ? -61.97497 -16.49264 1.51075   1.000 46.31016  ? 804  ARG   A N   1 
ATOM   956  C CA  . ARG   A 1 186 ? -62.14902 -15.60909 0.36086   1.000 49.04133  ? 804  ARG   A CA  1 
ATOM   957  C C   . ARG   A 1 186 ? -60.97215 -14.65450 0.21816   1.000 44.32637  ? 804  ARG   A C   1 
ATOM   958  O O   . ARG   A 1 186 ? -60.51198 -14.38615 -0.89799  1.000 44.72887  ? 804  ARG   A O   1 
ATOM   959  C CB  . ARG   A 1 186 ? -63.45745 -14.82518 0.47894   1.000 48.75217  ? 804  ARG   A CB  1 
ATOM   960  C CG  . ARG   A 1 186 ? -64.71523 -15.64487 0.26349   1.000 46.51787  ? 804  ARG   A CG  1 
ATOM   961  C CD  . ARG   A 1 186 ? -64.74762 -16.27348 -1.12148  1.000 53.67087  ? 804  ARG   A CD  1 
ATOM   962  N NE  . ARG   A 1 186 ? -66.08396 -16.75202 -1.46836  1.000 59.56606  ? 804  ARG   A NE  1 
ATOM   963  C CZ  . ARG   A 1 186 ? -66.34582 -17.59844 -2.45913  1.000 65.68230  ? 804  ARG   A CZ  1 
ATOM   964  N NH1 . ARG   A 1 186 ? -65.36168 -18.07899 -3.20759  1.000 68.49580  ? 804  ARG   A NH1 1 
ATOM   965  N NH2 . ARG   A 1 186 ? -67.59602 -17.97277 -2.69450  1.000 64.42436  ? 804  ARG   A NH2 1 
ATOM   966  N N   . GLY   A 1 187 ? -60.46775 -14.13767 1.33711   1.000 42.26416  ? 805  GLY   A N   1 
ATOM   967  C CA  . GLY   A 1 187 ? -59.29718 -13.27762 1.27331   1.000 48.21606  ? 805  GLY   A CA  1 
ATOM   968  C C   . GLY   A 1 187 ? -58.06488 -14.01595 0.79056   1.000 49.65478  ? 805  GLY   A C   1 
ATOM   969  O O   . GLY   A 1 187 ? -57.32388 -13.52144 -0.06336  1.000 49.86964  ? 805  GLY   A O   1 
ATOM   970  N N   . MET   A 1 188 ? -57.83068 -15.21531 1.33431   1.000 48.10858  ? 806  MET   A N   1 
ATOM   971  C CA  . MET   A 1 188 ? -56.68089 -16.00959 0.91359   1.000 47.91940  ? 806  MET   A CA  1 
ATOM   972  C C   . MET   A 1 188 ? -56.80778 -16.43271 -0.53981  1.000 51.19994  ? 806  MET   A C   1 
ATOM   973  O O   . MET   A 1 188 ? -55.80760 -16.50423 -1.26395  1.000 55.81805  ? 806  MET   A O   1 
ATOM   974  C CB  . MET   A 1 188 ? -56.52612 -17.23318 1.81734   1.000 48.52048  ? 806  MET   A CB  1 
ATOM   975  C CG  . MET   A 1 188 ? -56.04105 -16.90334 3.20796   1.000 48.07281  ? 806  MET   A CG  1 
ATOM   976  S SD  . MET   A 1 188 ? -54.57912 -15.84799 3.17329   1.000 52.35559  ? 806  MET   A SD  1 
ATOM   977  C CE  . MET   A 1 188 ? -53.42151 -16.87106 2.26105   1.000 47.95014  ? 806  MET   A CE  1 
ATOM   978  N N   . GLU   A 1 189 ? -58.03308 -16.71847 -0.98159  1.000 47.57510  ? 807  GLU   A N   1 
ATOM   979  C CA  . GLU   A 1 189 ? -58.27117 -16.98956 -2.39420  1.000 48.79202  ? 807  GLU   A CA  1 
ATOM   980  C C   . GLU   A 1 189 ? -57.83966 -15.81077 -3.25228  1.000 50.09503  ? 807  GLU   A C   1 
ATOM   981  O O   . GLU   A 1 189 ? -57.19515 -15.99061 -4.29206  1.000 52.78274  ? 807  GLU   A O   1 
ATOM   982  C CB  . GLU   A 1 189 ? -59.75065 -17.29940 -2.63455  1.000 46.12112  ? 807  GLU   A CB  1 
ATOM   983  C CG  . GLU   A 1 189 ? -60.07205 -17.53244 -4.09807  1.000 50.64070  ? 807  GLU   A CG  1 
ATOM   984  C CD  . GLU   A 1 189 ? -61.54427 -17.40630 -4.42545  1.000 54.05325  ? 807  GLU   A CD  1 
ATOM   985  O OE1 . GLU   A 1 189 ? -62.39045 -17.62424 -3.53162  1.000 53.78036  ? 807  GLU   A OE1 1 
ATOM   986  O OE2 . GLU   A 1 189 ? -61.84909 -17.09044 -5.59616  1.000 60.36325  ? 807  GLU   A OE2 1 
ATOM   987  N N   . PHE   A 1 190 ? -58.18664 -14.59179 -2.82990  1.000 54.56928  ? 808  PHE   A N   1 
ATOM   988  C CA  . PHE   A 1 190 ? -57.75259 -13.40814 -3.56397  1.000 57.78873  ? 808  PHE   A CA  1 
ATOM   989  C C   . PHE   A 1 190 ? -56.23148 -13.32754 -3.62719  1.000 53.08363  ? 808  PHE   A C   1 
ATOM   990  O O   . PHE   A 1 190 ? -55.65425 -13.11138 -4.69938  1.000 55.59461  ? 808  PHE   A O   1 
ATOM   991  C CB  . PHE   A 1 190 ? -58.32428 -12.14323 -2.92760  1.000 53.93649  ? 808  PHE   A CB  1 
ATOM   992  C CG  . PHE   A 1 190 ? -57.87222 -10.88039 -3.60449  1.000 55.97658  ? 808  PHE   A CG  1 
ATOM   993  C CD1 . PHE   A 1 190 ? -58.38276 -10.52887 -4.84282  1.000 57.26930  ? 808  PHE   A CD1 1 
ATOM   994  C CD2 . PHE   A 1 190 ? -56.92280 -10.05863 -3.01919  1.000 58.90727  ? 808  PHE   A CD2 1 
ATOM   995  C CE1 . PHE   A 1 190 ? -57.96859 -9.37375  -5.47714  1.000 65.34229  ? 808  PHE   A CE1 1 
ATOM   996  C CE2 . PHE   A 1 190 ? -56.50196 -8.89818  -3.64886  1.000 59.54448  ? 808  PHE   A CE2 1 
ATOM   997  C CZ  . PHE   A 1 190 ? -57.02743 -8.55681  -4.88018  1.000 64.40011  ? 808  PHE   A CZ  1 
ATOM   998  N N   . LEU   A 1 191 ? -55.56296 -13.49091 -2.48171  1.000 52.39299  ? 809  LEU   A N   1 
ATOM   999  C CA  . LEU   A 1 191 ? -54.10846 -13.36554 -2.45668  1.000 53.90857  ? 809  LEU   A CA  1 
ATOM   1000 C C   . LEU   A 1 191 ? -53.44981 -14.41732 -3.33547  1.000 56.56266  ? 809  LEU   A C   1 
ATOM   1001 O O   . LEU   A 1 191 ? -52.48450 -14.12409 -4.05340  1.000 58.54294  ? 809  LEU   A O   1 
ATOM   1002 C CB  . LEU   A 1 191 ? -53.59565 -13.46823 -1.02118  1.000 49.34768  ? 809  LEU   A CB  1 
ATOM   1003 C CG  . LEU   A 1 191 ? -54.00774 -12.32413 -0.09278  1.000 45.57964  ? 809  LEU   A CG  1 
ATOM   1004 C CD1 . LEU   A 1 191 ? -53.38750 -12.46112 1.29048   1.000 44.68347  ? 809  LEU   A CD1 1 
ATOM   1005 C CD2 . LEU   A 1 191 ? -53.64228 -10.99491 -0.72549  1.000 42.62143  ? 809  LEU   A CD2 1 
ATOM   1006 N N   . ALA   A 1 192 ? -53.96348 -15.64806 -3.29392  1.000 55.26662  ? 810  ALA   A N   1 
ATOM   1007 C CA  . ALA   A 1 192 ? -53.42481 -16.70752 -4.13820  1.000 54.05936  ? 810  ALA   A CA  1 
ATOM   1008 C C   . ALA   A 1 192 ? -53.58108 -16.36695 -5.61597  1.000 59.63447  ? 810  ALA   A C   1 
ATOM   1009 O O   . ALA   A 1 192 ? -52.66311 -16.59510 -6.41280  1.000 62.29765  ? 810  ALA   A O   1 
ATOM   1010 C CB  . ALA   A 1 192 ? -54.11911 -18.03195 -3.81109  1.000 51.30398  ? 810  ALA   A CB  1 
ATOM   1011 N N   . SER   A 1 193 ? -54.73474 -15.80262 -5.99697  1.000 61.48256  ? 811  SER   A N   1 
ATOM   1012 C CA  . SER   A 1 193 ? -54.95740 -15.38888 -7.37993  1.000 67.95947  ? 811  SER   A CA  1 
ATOM   1013 C C   . SER   A 1 193 ? -53.95343 -14.33975 -7.84047  1.000 71.57767  ? 811  SER   A C   1 
ATOM   1014 O O   . SER   A 1 193 ? -53.70851 -14.22238 -9.04549  1.000 76.50608  ? 811  SER   A O   1 
ATOM   1015 C CB  . SER   A 1 193 ? -56.38054 -14.85086 -7.55779  1.000 66.57773  ? 811  SER   A CB  1 
ATOM   1016 O OG  . SER   A 1 193 ? -56.55760 -13.62443 -6.87487  1.000 64.28033  ? 811  SER   A OG  1 
ATOM   1017 N N   . LYS   A 1 194 ? -53.36756 -13.58086 -6.91625  1.000 69.48460  ? 812  LYS   A N   1 
ATOM   1018 C CA  . LYS   A 1 194 ? -52.33106 -12.60836 -7.23270  1.000 78.32004  ? 812  LYS   A CA  1 
ATOM   1019 C C   . LYS   A 1 194 ? -50.92778 -13.17955 -7.06909  1.000 79.12418  ? 812  LYS   A C   1 
ATOM   1020 O O   . LYS   A 1 194 ? -49.95510 -12.42229 -7.13726  1.000 77.76953  ? 812  LYS   A O   1 
ATOM   1021 C CB  . LYS   A 1 194 ? -52.49378 -11.36489 -6.35590  1.000 76.35308  ? 812  LYS   A CB  1 
ATOM   1022 C CG  . LYS   A 1 194 ? -53.85888 -10.70328 -6.46638  1.000 75.31066  ? 812  LYS   A CG  1 
ATOM   1023 C CD  . LYS   A 1 194 ? -54.04275 -10.02076 -7.80937  1.000 82.82682  ? 812  LYS   A CD  1 
ATOM   1024 C CE  . LYS   A 1 194 ? -55.49230 -9.62377  -8.01578  1.000 85.65615  ? 812  LYS   A CE  1 
ATOM   1025 N NZ  . LYS   A 1 194 ? -55.62188 -8.32743  -8.73434  1.000 90.21959  ? 812  LYS   A NZ  1 
ATOM   1026 N N   . ASN   A 1 195 ? -50.81051 -14.49530 -6.86423  1.000 77.44411  ? 813  ASN   A N   1 
ATOM   1027 C CA  . ASN   A 1 195 ? -49.52977 -15.16706 -6.63789  1.000 79.58067  ? 813  ASN   A CA  1 
ATOM   1028 C C   . ASN   A 1 195 ? -48.79806 -14.57873 -5.43355  1.000 74.36183  ? 813  ASN   A C   1 
ATOM   1029 O O   . ASN   A 1 195 ? -47.57132 -14.44707 -5.42543  1.000 76.33853  ? 813  ASN   A O   1 
ATOM   1030 C CB  . ASN   A 1 195 ? -48.64858 -15.13827 -7.88892  1.000 86.54216  ? 813  ASN   A CB  1 
ATOM   1031 C CG  . ASN   A 1 195 ? -49.08272 -16.15369 -8.92483  1.000 99.46320  ? 813  ASN   A CG  1 
ATOM   1032 O OD1 . ASN   A 1 195 ? -48.96601 -17.36112 -8.71177  1.000 103.27662 ? 813  ASN   A OD1 1 
ATOM   1033 N ND2 . ASN   A 1 195 ? -49.57977 -15.67136 -10.05596 1.000 106.50279 ? 813  ASN   A ND2 1 
ATOM   1034 N N   . CYS   A 1 196 ? -49.56423 -14.22487 -4.40745  1.000 65.83492  ? 814  CYS   A N   1 
ATOM   1035 C CA  . CYS   A 1 196 ? -49.02965 -13.79944 -3.12204  1.000 63.49795  ? 814  CYS   A CA  1 
ATOM   1036 C C   . CYS   A 1 196 ? -49.16226 -14.95126 -2.13394  1.000 59.87931  ? 814  CYS   A C   1 
ATOM   1037 O O   . CYS   A 1 196 ? -50.27496 -15.41088 -1.86025  1.000 57.48871  ? 814  CYS   A O   1 
ATOM   1038 C CB  . CYS   A 1 196 ? -49.76839 -12.56408 -2.60633  1.000 63.20893  ? 814  CYS   A CB  1 
ATOM   1039 S SG  . CYS   A 1 196 ? -49.61679 -12.28079 -0.82280  1.000 62.34103  ? 814  CYS   A SG  1 
ATOM   1040 N N   . VAL   A 1 197 ? -48.03256 -15.42834 -1.62192  1.000 59.50937  ? 815  VAL   A N   1 
ATOM   1041 C CA  . VAL   A 1 197 ? -48.00506 -16.39505 -0.53216  1.000 55.49747  ? 815  VAL   A CA  1 
ATOM   1042 C C   . VAL   A 1 197 ? -47.85972 -15.61743 0.76606   1.000 56.19251  ? 815  VAL   A C   1 
ATOM   1043 O O   . VAL   A 1 197 ? -46.94846 -14.79066 0.90399   1.000 61.70697  ? 815  VAL   A O   1 
ATOM   1044 C CB  . VAL   A 1 197 ? -46.85918 -17.40537 -0.70489  1.000 56.13005  ? 815  VAL   A CB  1 
ATOM   1045 C CG1 . VAL   A 1 197 ? -46.88019 -18.42725 0.41807   1.000 59.02970  ? 815  VAL   A CG1 1 
ATOM   1046 C CG2 . VAL   A 1 197 ? -46.94975 -18.09233 -2.05681  1.000 56.91415  ? 815  VAL   A CG2 1 
ATOM   1047 N N   . HIS   A 1 198 ? -48.76203 -15.86514 1.71630   1.000 53.48996  ? 816  HIS   A N   1 
ATOM   1048 C CA  . HIS   A 1 198 ? -48.79202 -15.03155 2.91610   1.000 51.13058  ? 816  HIS   A CA  1 
ATOM   1049 C C   . HIS   A 1 198 ? -47.61380 -15.31425 3.83840   1.000 52.09753  ? 816  HIS   A C   1 
ATOM   1050 O O   . HIS   A 1 198 ? -46.94411 -14.38182 4.29932   1.000 54.93722  ? 816  HIS   A O   1 
ATOM   1051 C CB  . HIS   A 1 198 ? -50.10825 -15.21772 3.67073   1.000 44.87484  ? 816  HIS   A CB  1 
ATOM   1052 C CG  . HIS   A 1 198 ? -50.32532 -14.19660 4.74237   1.000 49.37885  ? 816  HIS   A CG  1 
ATOM   1053 N ND1 . HIS   A 1 198 ? -49.56924 -14.15978 5.89327   1.000 50.87539  ? 816  HIS   A ND1 1 
ATOM   1054 C CD2 . HIS   A 1 198 ? -51.19629 -13.16385 4.83166   1.000 49.87585  ? 816  HIS   A CD2 1 
ATOM   1055 C CE1 . HIS   A 1 198 ? -49.96637 -13.15213 6.64864   1.000 50.46504  ? 816  HIS   A CE1 1 
ATOM   1056 N NE2 . HIS   A 1 198 ? -50.95514 -12.53316 6.02881   1.000 50.25057  ? 816  HIS   A NE2 1 
ATOM   1057 N N   . ARG   A 1 199 ? -47.36972 -16.59228 4.13295   1.000 52.94601  ? 817  ARG   A N   1 
ATOM   1058 C CA  . ARG   A 1 199 ? -46.27069 -17.14929 4.92161   1.000 57.09594  ? 817  ARG   A CA  1 
ATOM   1059 C C   . ARG   A 1 199 ? -46.44093 -16.92306 6.42452   1.000 55.99621  ? 817  ARG   A C   1 
ATOM   1060 O O   . ARG   A 1 199 ? -45.68423 -17.50066 7.19915   1.000 58.46576  ? 817  ARG   A O   1 
ATOM   1061 C CB  . ARG   A 1 199 ? -44.88752 -16.61808 4.49126   1.000 58.58626  ? 817  ARG   A CB  1 
ATOM   1062 C CG  . ARG   A 1 199 ? -44.55741 -16.84076 3.01550   1.000 67.81408  ? 817  ARG   A CG  1 
ATOM   1063 C CD  . ARG   A 1 199 ? -43.37609 -15.97929 2.58451   1.000 75.75824  ? 817  ARG   A CD  1 
ATOM   1064 N NE  . ARG   A 1 199 ? -42.14211 -16.36385 3.25983   1.000 79.54496  ? 817  ARG   A NE  1 
ATOM   1065 C CZ  . ARG   A 1 199 ? -41.15296 -17.04219 2.68513   1.000 84.37276  ? 817  ARG   A CZ  1 
ATOM   1066 N NH1 . ARG   A 1 199 ? -41.23936 -17.40566 1.41277   1.000 86.93478  ? 817  ARG   A NH1 1 
ATOM   1067 N NH2 . ARG   A 1 199 ? -40.06978 -17.35120 3.38361   1.000 82.65767  ? 817  ARG   A NH2 1 
ATOM   1068 N N   . ASP   A 1 200 ? -47.40804 -16.11280 6.86545   1.000 54.93401  ? 818  ASP   A N   1 
ATOM   1069 C CA  . ASP   A 1 200 ? -47.63819 -15.88782 8.29057   1.000 51.81663  ? 818  ASP   A CA  1 
ATOM   1070 C C   . ASP   A 1 200 ? -49.13034 -15.77158 8.57224   1.000 50.60867  ? 818  ASP   A C   1 
ATOM   1071 O O   . ASP   A 1 200 ? -49.56693 -14.95255 9.38950   1.000 47.80787  ? 818  ASP   A O   1 
ATOM   1072 C CB  . ASP   A 1 200 ? -46.90176 -14.64568 8.79594   1.000 50.34917  ? 818  ASP   A CB  1 
ATOM   1073 C CG  . ASP   A 1 200 ? -46.73307 -14.64488 10.30106  1.000 53.84964  ? 818  ASP   A CG  1 
ATOM   1074 O OD1 . ASP   A 1 200 ? -47.11361 -15.65143 10.93612  1.000 52.19373  ? 818  ASP   A OD1 1 
ATOM   1075 O OD2 . ASP   A 1 200 ? -46.22793 -13.64469 10.85050  1.000 51.64876  ? 818  ASP   A OD2 1 
ATOM   1076 N N   . LEU   A 1 201 ? -49.93951 -16.58934 7.90037   1.000 49.82255  ? 819  LEU   A N   1 
ATOM   1077 C CA  . LEU   A 1 201 ? -51.36945 -16.58522 8.17638   1.000 48.73368  ? 819  LEU   A CA  1 
ATOM   1078 C C   . LEU   A 1 201 ? -51.62319 -17.14292 9.56512   1.000 50.54287  ? 819  LEU   A C   1 
ATOM   1079 O O   . LEU   A 1 201 ? -51.14843 -18.22925 9.90610   1.000 46.86325  ? 819  LEU   A O   1 
ATOM   1080 C CB  . LEU   A 1 201 ? -52.13792 -17.39219 7.12960   1.000 42.56523  ? 819  LEU   A CB  1 
ATOM   1081 C CG  . LEU   A 1 201 ? -53.65876 -17.31521 7.30152   1.000 46.40805  ? 819  LEU   A CG  1 
ATOM   1082 C CD1 . LEU   A 1 201 ? -54.13443 -15.87606 7.21441   1.000 40.17227  ? 819  LEU   A CD1 1 
ATOM   1083 C CD2 . LEU   A 1 201 ? -54.38450 -18.18581 6.29246   1.000 49.69179  ? 819  LEU   A CD2 1 
ATOM   1084 N N   . ALA   A 1 202 ? -52.37809 -16.38985 10.35618  1.000 47.78070  ? 820  ALA   A N   1 
ATOM   1085 C CA  . ALA   A 1 202 ? -52.65401 -16.65483 11.75918  1.000 47.29212  ? 820  ALA   A CA  1 
ATOM   1086 C C   . ALA   A 1 202 ? -53.71685 -15.65483 12.17814  1.000 48.23016  ? 820  ALA   A C   1 
ATOM   1087 O O   . ALA   A 1 202 ? -53.90863 -14.63275 11.51585  1.000 45.94257  ? 820  ALA   A O   1 
ATOM   1088 C CB  . ALA   A 1 202 ? -51.40061 -16.51439 12.62734  1.000 43.37204  ? 820  ALA   A CB  1 
ATOM   1089 N N   . ALA   A 1 203 ? -54.40893 -15.95864 13.27824  1.000 44.82731  ? 821  ALA   A N   1 
ATOM   1090 C CA  . ALA   A 1 203 ? -55.45225 -15.05825 13.75713  1.000 44.92264  ? 821  ALA   A CA  1 
ATOM   1091 C C   . ALA   A 1 203 ? -54.89239 -13.69654 14.14224  1.000 48.35450  ? 821  ALA   A C   1 
ATOM   1092 O O   . ALA   A 1 203 ? -55.58670 -12.67733 14.00660  1.000 48.83897  ? 821  ALA   A O   1 
ATOM   1093 C CB  . ALA   A 1 203 ? -56.19389 -15.69259 14.93216  1.000 41.77816  ? 821  ALA   A CB  1 
ATOM   1094 N N   . ARG   A 1 204 ? -53.64081 -13.65650 14.59871  1.000 46.68503  ? 822  ARG   A N   1 
ATOM   1095 C CA  . ARG   A 1 204 ? -52.99483 -12.39208 14.92025  1.000 49.78604  ? 822  ARG   A CA  1 
ATOM   1096 C C   . ARG   A 1 204 ? -52.76841 -11.52009 13.69735  1.000 50.60327  ? 822  ARG   A C   1 
ATOM   1097 O O   . ARG   A 1 204 ? -52.52974 -10.31995 13.85234  1.000 47.57432  ? 822  ARG   A O   1 
ATOM   1098 C CB  . ARG   A 1 204 ? -51.66382 -12.65177 15.61050  1.000 47.71572  ? 822  ARG   A CB  1 
ATOM   1099 C CG  . ARG   A 1 204 ? -50.65280 -13.29721 14.70939  1.000 50.64067  ? 822  ARG   A CG  1 
ATOM   1100 C CD  . ARG   A 1 204 ? -49.38530 -13.68283 15.44726  1.000 49.81033  ? 822  ARG   A CD  1 
ATOM   1101 N NE  . ARG   A 1 204 ? -48.55577 -14.53121 14.60359  1.000 50.48723  ? 822  ARG   A NE  1 
ATOM   1102 C CZ  . ARG   A 1 204 ? -48.60230 -15.85677 14.61819  1.000 51.99156  ? 822  ARG   A CZ  1 
ATOM   1103 N NH1 . ARG   A 1 204 ? -49.43371 -16.48441 15.43815  1.000 47.34750  ? 822  ARG   A NH1 1 
ATOM   1104 N NH2 . ARG   A 1 204 ? -47.81748 -16.55372 13.81331  1.000 50.98584  ? 822  ARG   A NH2 1 
ATOM   1105 N N   . ASN   A 1 205 ? -52.82586 -12.09168 12.49735  1.000 48.30342  ? 823  ASN   A N   1 
ATOM   1106 C CA  . ASN   A 1 205 ? -52.68531 -11.34426 11.25494  1.000 46.39705  ? 823  ASN   A CA  1 
ATOM   1107 C C   . ASN   A 1 205 ? -54.01036 -11.24022 10.50825  1.000 47.40081  ? 823  ASN   A C   1 
ATOM   1108 O O   . ASN   A 1 205 ? -54.03205 -11.11320 9.28256   1.000 48.62493  ? 823  ASN   A O   1 
ATOM   1109 C CB  . ASN   A 1 205 ? -51.60476 -11.96962 10.37336  1.000 47.23281  ? 823  ASN   A CB  1 
ATOM   1110 C CG  . ASN   A 1 205 ? -50.21080 -11.58197 10.81803  1.000 49.91328  ? 823  ASN   A CG  1 
ATOM   1111 O OD1 . ASN   A 1 205 ? -49.97379 -10.44801 11.22787  1.000 49.39616  ? 823  ASN   A OD1 1 
ATOM   1112 N ND2 . ASN   A 1 205 ? -49.27662 -12.52505 10.73775  1.000 51.01943  ? 823  ASN   A ND2 1 
ATOM   1113 N N   . VAL   A 1 206 ? -55.11704 -11.29311 11.24475  1.000 44.68883  ? 824  VAL   A N   1 
ATOM   1114 C CA  . VAL   A 1 206 ? -56.45097 -11.04201 10.71985  1.000 42.45625  ? 824  VAL   A CA  1 
ATOM   1115 C C   . VAL   A 1 206 ? -57.05820 -9.91734  11.54126  1.000 47.32426  ? 824  VAL   A C   1 
ATOM   1116 O O   . VAL   A 1 206 ? -57.16524 -10.02259 12.76931  1.000 50.58620  ? 824  VAL   A O   1 
ATOM   1117 C CB  . VAL   A 1 206 ? -57.33786 -12.29355 10.77286  1.000 42.11579  ? 824  VAL   A CB  1 
ATOM   1118 C CG1 . VAL   A 1 206 ? -58.75610 -11.94978 10.35509  1.000 48.25091  ? 824  VAL   A CG1 1 
ATOM   1119 C CG2 . VAL   A 1 206 ? -56.76228 -13.38489 9.88839   1.000 39.59754  ? 824  VAL   A CG2 1 
ATOM   1120 N N   . LEU   A 1 207 ? -57.43383 -8.84023  10.87257  1.000 44.16789  ? 825  LEU   A N   1 
ATOM   1121 C CA  . LEU   A 1 207 ? -58.11813 -7.73726  11.51922  1.000 45.37725  ? 825  LEU   A CA  1 
ATOM   1122 C C   . LEU   A 1 207 ? -59.61772 -7.86299  11.29181  1.000 46.84982  ? 825  LEU   A C   1 
ATOM   1123 O O   . LEU   A 1 207 ? -60.07626 -8.56188  10.38487  1.000 47.01823  ? 825  LEU   A O   1 
ATOM   1124 C CB  . LEU   A 1 207 ? -57.60478 -6.39920  10.99050  1.000 47.23224  ? 825  LEU   A CB  1 
ATOM   1125 C CG  . LEU   A 1 207 ? -56.11183 -6.13234  11.16185  1.000 55.12357  ? 825  LEU   A CG  1 
ATOM   1126 C CD1 . LEU   A 1 207 ? -55.77033 -4.75025  10.66474  1.000 51.95947  ? 825  LEU   A CD1 1 
ATOM   1127 C CD2 . LEU   A 1 207 ? -55.67325 -6.31000  12.60854  1.000 59.55018  ? 825  LEU   A CD2 1 
ATOM   1128 N N   . LEU   A 1 208 ? -60.38612 -7.19220  12.14690  1.000 49.35400  ? 826  LEU   A N   1 
ATOM   1129 C CA  . LEU   A 1 208 ? -61.84159 -7.21052  12.05559  1.000 50.58897  ? 826  LEU   A CA  1 
ATOM   1130 C C   . LEU   A 1 208 ? -62.34081 -5.77684  11.98273  1.000 52.06416  ? 826  LEU   A C   1 
ATOM   1131 O O   . LEU   A 1 208 ? -62.12505 -4.99315  12.91243  1.000 55.89770  ? 826  LEU   A O   1 
ATOM   1132 C CB  . LEU   A 1 208 ? -62.46914 -7.94463  13.24466  1.000 52.81573  ? 826  LEU   A CB  1 
ATOM   1133 C CG  . LEU   A 1 208 ? -63.87796 -8.48453  12.99767  1.000 58.21542  ? 826  LEU   A CG  1 
ATOM   1134 C CD1 . LEU   A 1 208 ? -63.86358 -9.52396  11.89040  1.000 52.16653  ? 826  LEU   A CD1 1 
ATOM   1135 C CD2 . LEU   A 1 208 ? -64.46741 -9.06323  14.26986  1.000 60.54073  ? 826  LEU   A CD2 1 
ATOM   1136 N N   . ALA   A 1 209 ? -62.98755 -5.43507  10.87711  1.000 49.45669  ? 827  ALA   A N   1 
ATOM   1137 C CA  . ALA   A 1 209 ? -63.61228 -4.13689  10.69647  1.000 56.87354  ? 827  ALA   A CA  1 
ATOM   1138 C C   . ALA   A 1 209 ? -65.07156 -4.20766  11.12795  1.000 56.72689  ? 827  ALA   A C   1 
ATOM   1139 O O   . ALA   A 1 209 ? -65.62361 -5.28068  11.38094  1.000 54.42292  ? 827  ALA   A O   1 
ATOM   1140 C CB  . ALA   A 1 209 ? -63.50456 -3.68657  9.23712   1.000 53.39673  ? 827  ALA   A CB  1 
ATOM   1141 N N   . GLN   A 1 210 ? -65.69821 -3.04090  11.20837  1.000 62.93634  ? 828  GLN   A N   1 
ATOM   1142 C CA  . GLN   A 1 210 ? -67.09392 -2.98795  11.59847  1.000 65.37278  ? 828  GLN   A CA  1 
ATOM   1143 C C   . GLN   A 1 210 ? -67.96978 -3.69045  10.56941  1.000 61.45034  ? 828  GLN   A C   1 
ATOM   1144 O O   . GLN   A 1 210 ? -67.59652 -3.87760  9.40814   1.000 60.90499  ? 828  GLN   A O   1 
ATOM   1145 C CB  . GLN   A 1 210 ? -67.54316 -1.54706  11.76130  1.000 68.70027  ? 828  GLN   A CB  1 
ATOM   1146 N N   . GLY   A 1 211 ? -69.16213 -4.06821  11.01460  1.000 60.81263  ? 829  GLY   A N   1 
ATOM   1147 C CA  . GLY   A 1 211 ? -69.91752 -5.06233  10.29327  1.000 59.53990  ? 829  GLY   A CA  1 
ATOM   1148 C C   . GLY   A 1 211 ? -69.30619 -6.44160  10.35374  1.000 55.18782  ? 829  GLY   A C   1 
ATOM   1149 O O   . GLY   A 1 211 ? -69.71814 -7.32028  9.58831   1.000 55.49414  ? 829  GLY   A O   1 
ATOM   1150 N N   . LYS   A 1 212 ? -68.31704 -6.64063  11.22964  1.000 54.91334  ? 830  LYS   A N   1 
ATOM   1151 C CA  . LYS   A 1 212 ? -67.65487 -7.92523  11.43335  1.000 51.35040  ? 830  LYS   A CA  1 
ATOM   1152 C C   . LYS   A 1 212 ? -67.07040 -8.45718  10.12951  1.000 54.31074  ? 830  LYS   A C   1 
ATOM   1153 O O   . LYS   A 1 212 ? -67.29307 -9.60396  9.73799   1.000 50.44697  ? 830  LYS   A O   1 
ATOM   1154 C CB  . LYS   A 1 212 ? -68.61242 -8.93267  12.07558  1.000 53.93153  ? 830  LYS   A CB  1 
ATOM   1155 C CG  . LYS   A 1 212 ? -69.08799 -8.51118  13.45785  1.000 64.27266  ? 830  LYS   A CG  1 
ATOM   1156 C CD  . LYS   A 1 212 ? -69.82204 -9.62577  14.18635  1.000 72.28785  ? 830  LYS   A CD  1 
ATOM   1157 C CE  . LYS   A 1 212 ? -70.24294 -9.16217  15.57565  1.000 80.41043  ? 830  LYS   A CE  1 
ATOM   1158 N NZ  . LYS   A 1 212 ? -71.22378 -10.06873 16.23302  1.000 84.48538  ? 830  LYS   A NZ  1 
ATOM   1159 N N   . ILE   A 1 213 ? -66.28084 -7.61511  9.47040   1.000 49.37603  ? 831  ILE   A N   1 
ATOM   1160 C CA  . ILE   A 1 213 ? -65.67738 -7.94965  8.18559   1.000 49.02668  ? 831  ILE   A CA  1 
ATOM   1161 C C   . ILE   A 1 213 ? -64.20579 -8.26304  8.40327   1.000 49.17909  ? 831  ILE   A C   1 
ATOM   1162 O O   . ILE   A 1 213 ? -63.45212 -7.42884  8.91869   1.000 54.97960  ? 831  ILE   A O   1 
ATOM   1163 C CB  . ILE   A 1 213 ? -65.86012 -6.81767  7.16308   1.000 55.70689  ? 831  ILE   A CB  1 
ATOM   1164 C CG1 . ILE   A 1 213 ? -67.34498 -6.63983  6.83818   1.000 60.67923  ? 831  ILE   A CG1 1 
ATOM   1165 C CG2 . ILE   A 1 213 ? -65.09268 -7.11884  5.89578   1.000 53.64427  ? 831  ILE   A CG2 1 
ATOM   1166 C CD1 . ILE   A 1 213 ? -67.63919 -5.44993  5.95500   1.000 68.03849  ? 831  ILE   A CD1 1 
ATOM   1167 N N   . VAL   A 1 214 ? -63.80598 -9.47018  8.00544   1.000 48.82956  ? 832  VAL   A N   1 
ATOM   1168 C CA  . VAL   A 1 214 ? -62.42700 -9.90871  8.14756   1.000 48.70465  ? 832  VAL   A CA  1 
ATOM   1169 C C   . VAL   A 1 214 ? -61.53359 -9.13668  7.18639   1.000 49.27054  ? 832  VAL   A C   1 
ATOM   1170 O O   . VAL   A 1 214 ? -61.89123 -8.90394  6.02523   1.000 51.63069  ? 832  VAL   A O   1 
ATOM   1171 C CB  . VAL   A 1 214 ? -62.34459 -11.42495 7.90123   1.000 51.14532  ? 832  VAL   A CB  1 
ATOM   1172 C CG1 . VAL   A 1 214 ? -60.94087 -11.83586 7.49850   1.000 52.24194  ? 832  VAL   A CG1 1 
ATOM   1173 C CG2 . VAL   A 1 214 ? -62.79464 -12.18892 9.13769   1.000 43.32774  ? 832  VAL   A CG2 1 
ATOM   1174 N N   . LYS   A 1 215 ? -60.35959 -8.73331  7.66824   1.000 46.87033  ? 833  LYS   A N   1 
ATOM   1175 C CA  . LYS   A 1 215 ? -59.33567 -8.09451  6.83994   1.000 47.74289  ? 833  LYS   A CA  1 
ATOM   1176 C C   . LYS   A 1 215 ? -58.00267 -8.77798  7.13634   1.000 49.93225  ? 833  LYS   A C   1 
ATOM   1177 O O   . LYS   A 1 215 ? -57.39631 -8.53786  8.18370   1.000 51.14607  ? 833  LYS   A O   1 
ATOM   1178 C CB  . LYS   A 1 215 ? -59.24503 -6.59304  7.10594   1.000 47.72849  ? 833  LYS   A CB  1 
ATOM   1179 C CG  . LYS   A 1 215 ? -60.57145 -5.84509  7.03529   1.000 52.91219  ? 833  LYS   A CG  1 
ATOM   1180 C CD  . LYS   A 1 215 ? -60.90966 -5.38342  5.62368   1.000 53.08565  ? 833  LYS   A CD  1 
ATOM   1181 C CE  . LYS   A 1 215 ? -62.24220 -4.65437  5.58894   1.000 52.63520  ? 833  LYS   A CE  1 
ATOM   1182 N NZ  . LYS   A 1 215 ? -62.67327 -4.31563  4.19945   1.000 50.28674  ? 833  LYS   A NZ  1 
ATOM   1183 N N   . ILE   A 1 216 ? -57.53807 -9.62331  6.21473   1.000 51.87680  ? 834  ILE   A N   1 
ATOM   1184 C CA  . ILE   A 1 216 ? -56.22141 -10.23633 6.35893   1.000 48.04963  ? 834  ILE   A CA  1 
ATOM   1185 C C   . ILE   A 1 216 ? -55.14798 -9.16431  6.26056   1.000 50.15589  ? 834  ILE   A C   1 
ATOM   1186 O O   . ILE   A 1 216 ? -55.22951 -8.24616  5.43387   1.000 52.80039  ? 834  ILE   A O   1 
ATOM   1187 C CB  . ILE   A 1 216 ? -56.00364 -11.32812 5.29651   1.000 47.49343  ? 834  ILE   A CB  1 
ATOM   1188 C CG1 . ILE   A 1 216 ? -57.04871 -12.43323 5.45339   1.000 45.06345  ? 834  ILE   A CG1 1 
ATOM   1189 C CG2 . ILE   A 1 216 ? -54.58734 -11.89929 5.37621   1.000 47.78808  ? 834  ILE   A CG2 1 
ATOM   1190 C CD1 . ILE   A 1 216 ? -57.04262 -13.43869 4.32874   1.000 47.46872  ? 834  ILE   A CD1 1 
ATOM   1191 N N   . CYS   A 1 217 ? -54.12718 -9.28310  7.10298   1.000 46.69940  ? 835  CYS   A N   1 
ATOM   1192 C CA  . CYS   A 1 217 ? -53.03436 -8.32943  7.13353   1.000 49.92397  ? 835  CYS   A CA  1 
ATOM   1193 C C   . CYS   A 1 217 ? -51.73173 -9.06705  7.40332   1.000 49.94628  ? 835  CYS   A C   1 
ATOM   1194 O O   . CYS   A 1 217 ? -51.70667 -10.28256 7.60990   1.000 46.12289  ? 835  CYS   A O   1 
ATOM   1195 C CB  . CYS   A 1 217 ? -53.26859 -7.25022  8.19671   1.000 50.78376  ? 835  CYS   A CB  1 
ATOM   1196 S SG  . CYS   A 1 217 ? -53.10758 -7.84263  9.90411   1.000 54.19970  ? 835  CYS   A SG  1 
ATOM   1197 N N   . ASP   A 1 218 ? -50.63961 -8.30780  7.39078   1.000 57.02965  ? 836  ASP   A N   1 
ATOM   1198 C CA  . ASP   A 1 218 ? -49.32974 -8.77999  7.82508   1.000 57.76257  ? 836  ASP   A CA  1 
ATOM   1199 C C   . ASP   A 1 218 ? -48.63847 -7.60831  8.49901   1.000 58.67815  ? 836  ASP   A C   1 
ATOM   1200 O O   . ASP   A 1 218 ? -48.30187 -6.62621  7.83147   1.000 61.58839  ? 836  ASP   A O   1 
ATOM   1201 C CB  . ASP   A 1 218 ? -48.49658 -9.30411  6.64699   1.000 60.14533  ? 836  ASP   A CB  1 
ATOM   1202 C CG  . ASP   A 1 218 ? -47.24680 -10.04503 7.09448   1.000 63.02335  ? 836  ASP   A CG  1 
ATOM   1203 O OD1 . ASP   A 1 218 ? -46.93727 -10.01797 8.30586   1.000 62.47592  ? 836  ASP   A OD1 1 
ATOM   1204 O OD2 . ASP   A 1 218 ? -46.58312 -10.67075 6.24409   1.000 65.35437  ? 836  ASP   A OD2 1 
ATOM   1205 N N   . PHE   A 1 219 ? -48.44842 -7.70354  9.81717   1.000 55.89374  ? 837  PHE   A N   1 
ATOM   1206 C CA  . PHE   A 1 219 ? -47.76840 -6.63659  10.54149  1.000 60.94399  ? 837  PHE   A CA  1 
ATOM   1207 C C   . PHE   A 1 219 ? -46.29178 -6.55930  10.17546  1.000 63.86287  ? 837  PHE   A C   1 
ATOM   1208 O O   . PHE   A 1 219 ? -45.73136 -5.45691  10.10593  1.000 65.10011  ? 837  PHE   A O   1 
ATOM   1209 C CB  . PHE   A 1 219 ? -47.94326 -6.83523  12.04720  1.000 65.10943  ? 837  PHE   A CB  1 
ATOM   1210 C CG  . PHE   A 1 219 ? -49.27585 -6.37234  12.57177  1.000 66.93347  ? 837  PHE   A CG  1 
ATOM   1211 C CD1 . PHE   A 1 219 ? -49.45608 -5.05872  12.97467  1.000 76.25261  ? 837  PHE   A CD1 1 
ATOM   1212 C CD2 . PHE   A 1 219 ? -50.34866 -7.24629  12.65711  1.000 63.67754  ? 837  PHE   A CD2 1 
ATOM   1213 C CE1 . PHE   A 1 219 ? -50.67799 -4.62595  13.45383  1.000 78.72841  ? 837  PHE   A CE1 1 
ATOM   1214 C CE2 . PHE   A 1 219 ? -51.57365 -6.81600  13.13557  1.000 66.53665  ? 837  PHE   A CE2 1 
ATOM   1215 C CZ  . PHE   A 1 219 ? -51.73687 -5.50769  13.53501  1.000 73.84945  ? 837  PHE   A CZ  1 
ATOM   1216 N N   . GLY   A 1 220 ? -45.65692 -7.70393  9.93442   1.000 61.08739  ? 838  GLY   A N   1 
ATOM   1217 C CA  . GLY   A 1 220 ? -44.27252 -7.71394  9.48791   1.000 63.07848  ? 838  GLY   A CA  1 
ATOM   1218 C C   . GLY   A 1 220 ? -43.34963 -7.04892  10.48883  1.000 68.60936  ? 838  GLY   A C   1 
ATOM   1219 O O   . GLY   A 1 220 ? -43.23484 -7.47643  11.64385  1.000 70.91382  ? 838  GLY   A O   1 
ATOM   1220 N N   . LEU   A 1 221 ? -42.68223 -5.97816  10.04603  1.000 76.09062  ? 839  LEU   A N   1 
ATOM   1221 C CA  . LEU   A 1 221 ? -41.73609 -5.26841  10.90248  1.000 80.03990  ? 839  LEU   A CA  1 
ATOM   1222 C C   . LEU   A 1 221 ? -42.40129 -4.67456  12.13693  1.000 79.62820  ? 839  LEU   A C   1 
ATOM   1223 O O   . LEU   A 1 221 ? -41.70843 -4.35474  13.10876  1.000 83.86148  ? 839  LEU   A O   1 
ATOM   1224 C CB  . LEU   A 1 221 ? -41.03640 -4.15459  10.11657  1.000 85.10961  ? 839  LEU   A CB  1 
ATOM   1225 C CG  . LEU   A 1 221 ? -39.82505 -4.50000  9.23973   1.000 89.43332  ? 839  LEU   A CG  1 
ATOM   1226 C CD1 . LEU   A 1 221 ? -38.75871 -5.22495  10.05369  1.000 90.82384  ? 839  LEU   A CD1 1 
ATOM   1227 C CD2 . LEU   A 1 221 ? -40.21990 -5.30549  8.01147   1.000 89.61896  ? 839  LEU   A CD2 1 
ATOM   1228 N N   . ALA   A 1 222 ? -43.72353 -4.51859  12.12235  1.000 75.50196  ? 840  ALA   A N   1 
ATOM   1229 C CA  . ALA   A 1 222 ? -44.45802 -3.92756  13.22940  1.000 76.46120  ? 840  ALA   A CA  1 
ATOM   1230 C C   . ALA   A 1 222 ? -44.87982 -4.95537  14.27275  1.000 75.00653  ? 840  ALA   A C   1 
ATOM   1231 O O   . ALA   A 1 222 ? -45.72548 -4.65257  15.12259  1.000 80.83973  ? 840  ALA   A O   1 
ATOM   1232 C CB  . ALA   A 1 222 ? -45.68233 -3.17677  12.70198  1.000 76.00824  ? 840  ALA   A CB  1 
ATOM   1233 N N   . ARG   A 1 223 ? -44.32348 -6.16178  14.21938  1.000 70.47179  ? 841  ARG   A N   1 
ATOM   1234 C CA  . ARG   A 1 223 ? -44.44904 -7.14188  15.28885  1.000 71.06489  ? 841  ARG   A CA  1 
ATOM   1235 C C   . ARG   A 1 223 ? -43.05730 -7.50347  15.78994  1.000 71.43253  ? 841  ARG   A C   1 
ATOM   1236 O O   . ARG   A 1 223 ? -42.12371 -7.66100  14.99624  1.000 71.04340  ? 841  ARG   A O   1 
ATOM   1237 C CB  . ARG   A 1 223 ? -45.18841 -8.40510  14.82830  1.000 71.31516  ? 841  ARG   A CB  1 
ATOM   1238 C CG  . ARG   A 1 223 ? -45.29867 -9.46432  15.92055  1.000 72.48338  ? 841  ARG   A CG  1 
ATOM   1239 C CD  . ARG   A 1 223 ? -46.14617 -10.64898 15.49758  1.000 71.56285  ? 841  ARG   A CD  1 
ATOM   1240 N NE  . ARG   A 1 223 ? -47.56568 -10.32113 15.41528  1.000 69.72054  ? 841  ARG   A NE  1 
ATOM   1241 C CZ  . ARG   A 1 223 ? -48.24520 -10.23697 14.27846  1.000 67.69689  ? 841  ARG   A CZ  1 
ATOM   1242 N NH1 . ARG   A 1 223 ? -47.64191 -10.45710 13.11755  1.000 69.04896  ? 841  ARG   A NH1 1 
ATOM   1243 N NH2 . ARG   A 1 223 ? -49.53414 -9.93603  14.30088  1.000 63.06677  ? 841  ARG   A NH2 1 
ATOM   1244 N N   . ASP   A 1 224 ? -42.91552 -7.61449  17.11197  1.000 71.04372  ? 842  ASP   A N   1 
ATOM   1245 C CA  . ASP   A 1 224 ? -41.63437 -7.96681  17.72309  1.000 76.97829  ? 842  ASP   A CA  1 
ATOM   1246 C C   . ASP   A 1 224 ? -41.54988 -9.48663  17.81740  1.000 74.77700  ? 842  ASP   A C   1 
ATOM   1247 O O   . ASP   A 1 224 ? -41.80291 -10.09927 18.85640  1.000 77.45009  ? 842  ASP   A O   1 
ATOM   1248 C CB  . ASP   A 1 224 ? -41.48352 -7.30095  19.08487  1.000 83.10417  ? 842  ASP   A CB  1 
ATOM   1249 C CG  . ASP   A 1 224 ? -40.08963 -7.45988  19.65937  1.000 93.02262  ? 842  ASP   A CG  1 
ATOM   1250 O OD1 . ASP   A 1 224 ? -39.14762 -7.69856  18.87572  1.000 96.36633  ? 842  ASP   A OD1 1 
ATOM   1251 O OD2 . ASP   A 1 224 ? -39.93716 -7.36193  20.89649  1.000 98.30376  ? 842  ASP   A OD2 1 
ATOM   1252 N N   . ILE   A 1 225 ? -41.17156 -10.10193 16.69406  1.000 68.46183  ? 843  ILE   A N   1 
ATOM   1253 C CA  . ILE   A 1 225 ? -41.09603 -11.55665 16.61380  1.000 70.12149  ? 843  ILE   A CA  1 
ATOM   1254 C C   . ILE   A 1 225 ? -39.98272 -12.14020 17.46893  1.000 73.60654  ? 843  ILE   A C   1 
ATOM   1255 O O   . ILE   A 1 225 ? -39.94652 -13.35792 17.67676  1.000 76.66322  ? 843  ILE   A O   1 
ATOM   1256 C CB  . ILE   A 1 225 ? -40.92267 -12.00990 15.14855  1.000 67.45466  ? 843  ILE   A CB  1 
ATOM   1257 C CG1 . ILE   A 1 225 ? -39.62051 -11.46493 14.55650  1.000 71.47631  ? 843  ILE   A CG1 1 
ATOM   1258 C CG2 . ILE   A 1 225 ? -42.11093 -11.56728 14.31156  1.000 62.29847  ? 843  ILE   A CG2 1 
ATOM   1259 C CD1 . ILE   A 1 225 ? -39.30136 -12.00919 13.17474  1.000 73.54719  ? 843  ILE   A CD1 1 
ATOM   1260 N N   . MET   A 1 226 ? -39.07885 -11.30364 17.97902  1.000 79.16926  ? 844  MET   A N   1 
ATOM   1261 C CA  . MET   A 1 226 ? -38.00645 -11.77258 18.84882  1.000 86.21307  ? 844  MET   A CA  1 
ATOM   1262 C C   . MET   A 1 226 ? -38.46522 -11.97864 20.28622  1.000 86.54790  ? 844  MET   A C   1 
ATOM   1263 O O   . MET   A 1 226 ? -37.82164 -12.73029 21.02411  1.000 91.38241  ? 844  MET   A O   1 
ATOM   1264 C CB  . MET   A 1 226 ? -36.84052 -10.78113 18.81975  1.000 93.98948  ? 844  MET   A CB  1 
ATOM   1265 C CG  . MET   A 1 226 ? -36.33397 -10.47173 17.41711  1.000 101.14285 ? 844  MET   A CG  1 
ATOM   1266 S SD  . MET   A 1 226 ? -35.27190 -9.01708  17.34581  1.000 115.96633 ? 844  MET   A SD  1 
ATOM   1267 C CE  . MET   A 1 226 ? -33.90253 -9.53961  18.37041  1.000 120.38442 ? 844  MET   A CE  1 
ATOM   1268 N N   . HIS   A 1 227 ? -39.54983 -11.32306 20.70449  1.000 83.44312  ? 845  HIS   A N   1 
ATOM   1269 C CA  . HIS   A 1 227 ? -40.07706 -11.45724 22.05754  1.000 85.32250  ? 845  HIS   A CA  1 
ATOM   1270 C C   . HIS   A 1 227 ? -41.53272 -11.91383 22.04376  1.000 84.32274  ? 845  HIS   A C   1 
ATOM   1271 O O   . HIS   A 1 227 ? -42.28630 -11.63670 22.97826  1.000 88.02210  ? 845  HIS   A O   1 
ATOM   1272 C CB  . HIS   A 1 227 ? -39.92925 -10.14517 22.82883  1.000 87.24041  ? 845  HIS   A CB  1 
ATOM   1273 C CG  . HIS   A 1 227 ? -38.53544 -9.59953  22.82390  1.000 89.78793  ? 845  HIS   A CG  1 
ATOM   1274 N ND1 . HIS   A 1 227 ? -38.17887 -8.47887  22.10562  1.000 90.20665  ? 845  HIS   A ND1 1 
ATOM   1275 C CD2 . HIS   A 1 227 ? -37.40790 -10.02360 23.44287  1.000 93.15867  ? 845  HIS   A CD2 1 
ATOM   1276 C CE1 . HIS   A 1 227 ? -36.89302 -8.23361  22.28407  1.000 93.06706  ? 845  HIS   A CE1 1 
ATOM   1277 N NE2 . HIS   A 1 227 ? -36.40155 -9.15615  23.09159  1.000 94.69323  ? 845  HIS   A NE2 1 
ATOM   1278 N N   . ASP   A 1 228 ? -41.93957 -12.61156 20.98684  1.000 81.11529  ? 846  ASP   A N   1 
ATOM   1279 C CA  . ASP   A 1 228 ? -43.27861 -13.17336 20.86740  1.000 76.95655  ? 846  ASP   A CA  1 
ATOM   1280 C C   . ASP   A 1 228 ? -43.15394 -14.68937 20.89600  1.000 75.39761  ? 846  ASP   A C   1 
ATOM   1281 O O   . ASP   A 1 228 ? -42.46528 -15.27461 20.05309  1.000 76.21253  ? 846  ASP   A O   1 
ATOM   1282 C CB  . ASP   A 1 228 ? -43.96566 -12.70676 19.58157  1.000 75.13937  ? 846  ASP   A CB  1 
ATOM   1283 C CG  . ASP   A 1 228 ? -45.44024 -13.08976 19.52865  1.000 75.19302  ? 846  ASP   A CG  1 
ATOM   1284 O OD1 . ASP   A 1 228 ? -45.77882 -14.25599 19.82297  1.000 74.52383  ? 846  ASP   A OD1 1 
ATOM   1285 O OD2 . ASP   A 1 228 ? -46.26878 -12.21905 19.18847  1.000 76.58009  ? 846  ASP   A OD2 1 
ATOM   1286 N N   . SER   A 1 229 ? -43.82599 -15.31933 21.86056  1.000 74.17402  ? 847  SER   A N   1 
ATOM   1287 C CA  . SER   A 1 229 ? -43.72618 -16.76458 22.02354  1.000 76.56105  ? 847  SER   A CA  1 
ATOM   1288 C C   . SER   A 1 229 ? -44.23760 -17.52813 20.80800  1.000 72.14352  ? 847  SER   A C   1 
ATOM   1289 O O   . SER   A 1 229 ? -43.85415 -18.68599 20.61393  1.000 74.16249  ? 847  SER   A O   1 
ATOM   1290 C CB  . SER   A 1 229 ? -44.49474 -17.20214 23.26969  1.000 81.77202  ? 847  SER   A CB  1 
ATOM   1291 O OG  . SER   A 1 229 ? -45.87997 -16.92536 23.13503  1.000 81.71765  ? 847  SER   A OG  1 
ATOM   1292 N N   . ASN   A 1 230 ? -45.08590 -16.91029 19.98418  1.000 64.71586  ? 848  ASN   A N   1 
ATOM   1293 C CA  . ASN   A 1 230 ? -45.58207 -17.56703 18.78377  1.000 62.89147  ? 848  ASN   A CA  1 
ATOM   1294 C C   . ASN   A 1 230 ? -44.51960 -17.68634 17.70144  1.000 60.02975  ? 848  ASN   A C   1 
ATOM   1295 O O   . ASN   A 1 230 ? -44.73738 -18.40718 16.72368  1.000 58.60800  ? 848  ASN   A O   1 
ATOM   1296 C CB  . ASN   A 1 230 ? -46.79042 -16.80925 18.23232  1.000 61.43431  ? 848  ASN   A CB  1 
ATOM   1297 C CG  . ASN   A 1 230 ? -47.95620 -16.78369 19.20299  1.000 70.35957  ? 848  ASN   A CG  1 
ATOM   1298 O OD1 . ASN   A 1 230 ? -48.27048 -17.79064 19.84245  1.000 69.70644  ? 848  ASN   A OD1 1 
ATOM   1299 N ND2 . ASN   A 1 230 ? -48.60795 -15.63308 19.31406  1.000 82.84172  ? 848  ASN   A ND2 1 
ATOM   1300 N N   . TYR   A 1 231 ? -43.38908 -16.99931 17.84291  1.000 61.84775  ? 849  TYR   A N   1 
ATOM   1301 C CA  . TYR   A 1 231 ? -42.29454 -17.06477 16.88222  1.000 61.82389  ? 849  TYR   A CA  1 
ATOM   1302 C C   . TYR   A 1 231 ? -41.09361 -17.70303 17.56267  1.000 66.26516  ? 849  TYR   A C   1 
ATOM   1303 O O   . TYR   A 1 231 ? -40.60389 -17.19225 18.57610  1.000 73.25023  ? 849  TYR   A O   1 
ATOM   1304 C CB  . TYR   A 1 231 ? -41.95172 -15.67392 16.34383  1.000 60.13662  ? 849  TYR   A CB  1 
ATOM   1305 C CG  . TYR   A 1 231 ? -43.08608 -15.05862 15.56232  1.000 58.22849  ? 849  TYR   A CG  1 
ATOM   1306 C CD1 . TYR   A 1 231 ? -44.16691 -14.47898 16.21348  1.000 58.03112  ? 849  TYR   A CD1 1 
ATOM   1307 C CD2 . TYR   A 1 231 ? -43.08877 -15.07358 14.17410  1.000 57.30355  ? 849  TYR   A CD2 1 
ATOM   1308 C CE1 . TYR   A 1 231 ? -45.21229 -13.92184 15.50627  1.000 55.97801  ? 849  TYR   A CE1 1 
ATOM   1309 C CE2 . TYR   A 1 231 ? -44.12832 -14.51445 13.45699  1.000 53.49236  ? 849  TYR   A CE2 1 
ATOM   1310 C CZ  . TYR   A 1 231 ? -45.18713 -13.94058 14.12817  1.000 54.39509  ? 849  TYR   A CZ  1 
ATOM   1311 O OH  . TYR   A 1 231 ? -46.23043 -13.38873 13.41899  1.000 52.92616  ? 849  TYR   A OH  1 
ATOM   1312 N N   . VAL   A 1 232 ? -40.63157 -18.81956 17.01084  1.000 63.79950  ? 850  VAL   A N   1 
ATOM   1313 C CA  . VAL   A 1 232 ? -39.57285 -19.62740 17.60238  1.000 65.30463  ? 850  VAL   A CA  1 
ATOM   1314 C C   . VAL   A 1 232 ? -38.27850 -19.35611 16.85281  1.000 68.86920  ? 850  VAL   A C   1 
ATOM   1315 O O   . VAL   A 1 232 ? -38.26780 -19.29872 15.61769  1.000 69.46791  ? 850  VAL   A O   1 
ATOM   1316 C CB  . VAL   A 1 232 ? -39.93273 -21.12729 17.55982  1.000 64.23618  ? 850  VAL   A CB  1 
ATOM   1317 C CG1 . VAL   A 1 232 ? -38.87083 -21.96248 18.25340  1.000 68.28476  ? 850  VAL   A CG1 1 
ATOM   1318 C CG2 . VAL   A 1 232 ? -41.30115 -21.36162 18.18674  1.000 60.77876  ? 850  VAL   A CG2 1 
ATOM   1319 N N   . SER   A 1 233 ? -37.18940 -19.18818 17.60039  1.000 73.92267  ? 851  SER   A N   1 
ATOM   1320 C CA  . SER   A 1 233 ? -35.88057 -19.02379 16.98296  1.000 79.47920  ? 851  SER   A CA  1 
ATOM   1321 C C   . SER   A 1 233 ? -35.52609 -20.26532 16.17676  1.000 85.12490  ? 851  SER   A C   1 
ATOM   1322 O O   . SER   A 1 233 ? -35.62326 -21.39196 16.67112  1.000 86.09495  ? 851  SER   A O   1 
ATOM   1323 C CB  . SER   A 1 233 ? -34.81512 -18.76130 18.05128  1.000 79.79449  ? 851  SER   A CB  1 
ATOM   1324 O OG  . SER   A 1 233 ? -33.51009 -18.75587 17.48890  1.000 82.07503  ? 851  SER   A OG  1 
ATOM   1325 N N   . LYS   A 1 234 ? -35.13323 -20.05647 14.92460  1.000 89.22872  ? 852  LYS   A N   1 
ATOM   1326 C CA  . LYS   A 1 234 ? -34.63131 -21.14502 14.09332  1.000 96.53755  ? 852  LYS   A CA  1 
ATOM   1327 C C   . LYS   A 1 234 ? -33.68743 -20.53119 13.07262  1.000 104.78017 ? 852  LYS   A C   1 
ATOM   1328 O O   . LYS   A 1 234 ? -34.11434 -19.73748 12.22771  1.000 105.08206 ? 852  LYS   A O   1 
ATOM   1329 C CB  . LYS   A 1 234 ? -35.76949 -21.90848 13.41772  1.000 95.24257  ? 852  LYS   A CB  1 
ATOM   1330 C CG  . LYS   A 1 234 ? -35.36055 -23.26880 12.88994  1.000 97.32669  ? 852  LYS   A CG  1 
ATOM   1331 C CD  . LYS   A 1 234 ? -36.56349 -24.16915 12.69825  1.000 94.81093  ? 852  LYS   A CD  1 
ATOM   1332 C CE  . LYS   A 1 234 ? -36.38377 -25.06786 11.49018  1.000 94.73099  ? 852  LYS   A CE  1 
ATOM   1333 N NZ  . LYS   A 1 234 ? -36.57896 -24.29643 10.23361  1.000 93.52176  ? 852  LYS   A NZ  1 
ATOM   1334 N N   . GLY   A 1 235 ? -32.40922 -20.88286 13.16856  1.000 109.00225 ? 853  GLY   A N   1 
ATOM   1335 C CA  . GLY   A 1 235 ? -31.40646 -20.30420 12.29899  1.000 112.51886 ? 853  GLY   A CA  1 
ATOM   1336 C C   . GLY   A 1 235 ? -31.15850 -18.83721 12.57940  1.000 113.31680 ? 853  GLY   A C   1 
ATOM   1337 O O   . GLY   A 1 235 ? -30.79166 -18.46155 13.69745  1.000 113.87651 ? 853  GLY   A O   1 
ATOM   1338 N N   . SER   A 1 236 ? -31.37178 -17.99478 11.56805  1.000 116.32941 ? 854  SER   A N   1 
ATOM   1339 C CA  . SER   A 1 236 ? -31.06281 -16.57543 11.66352  1.000 120.15073 ? 854  SER   A CA  1 
ATOM   1340 C C   . SER   A 1 236 ? -32.23096 -15.72675 12.14105  1.000 115.41925 ? 854  SER   A C   1 
ATOM   1341 O O   . SER   A 1 236 ? -32.01499 -14.56623 12.50285  1.000 118.92653 ? 854  SER   A O   1 
ATOM   1342 C CB  . SER   A 1 236 ? -30.58751 -16.05023 10.30518  1.000 127.10674 ? 854  SER   A CB  1 
ATOM   1343 O OG  . SER   A 1 236 ? -30.34436 -14.65522 10.35313  1.000 130.61471 ? 854  SER   A OG  1 
ATOM   1344 N N   . THR   A 1 237 ? -33.45253 -16.25895 12.15079  1.000 107.30193 ? 855  THR   A N   1 
ATOM   1345 C CA  . THR   A 1 237 ? -34.62506 -15.45368 12.46004  1.000 99.92369  ? 855  THR   A CA  1 
ATOM   1346 C C   . THR   A 1 237 ? -35.61918 -16.28151 13.26246  1.000 92.20377  ? 855  THR   A C   1 
ATOM   1347 O O   . THR   A 1 237 ? -35.38064 -17.45130 13.58058  1.000 93.73052  ? 855  THR   A O   1 
ATOM   1348 C CB  . THR   A 1 237 ? -35.27608 -14.91098 11.18211  1.000 98.49034  ? 855  THR   A CB  1 
ATOM   1349 O OG1 . THR   A 1 237 ? -36.45904 -14.17447 11.51954  1.000 95.20080  ? 855  THR   A OG1 1 
ATOM   1350 C CG2 . THR   A 1 237 ? -35.64216 -16.05442 10.24590  1.000 94.93576  ? 855  THR   A CG2 1 
ATOM   1351 N N   . PHE   A 1 238 ? -36.74801 -15.65576 13.58127  1.000 84.00294  ? 856  PHE   A N   1 
ATOM   1352 C CA  . PHE   A 1 238 ? -37.80419 -16.26445 14.37408  1.000 73.64941  ? 856  PHE   A CA  1 
ATOM   1353 C C   . PHE   A 1 238 ? -38.98896 -16.59012 13.47352  1.000 68.58205  ? 856  PHE   A C   1 
ATOM   1354 O O   . PHE   A 1 238 ? -39.34562 -15.80503 12.58980  1.000 68.90806  ? 856  PHE   A O   1 
ATOM   1355 C CB  . PHE   A 1 238 ? -38.23239 -15.33239 15.50916  1.000 71.19417  ? 856  PHE   A CB  1 
ATOM   1356 C CG  . PHE   A 1 238 ? -37.11854 -14.98541 16.46335  1.000 75.93344  ? 856  PHE   A CG  1 
ATOM   1357 C CD1 . PHE   A 1 238 ? -36.17498 -14.02380 16.13356  1.000 79.77128  ? 856  PHE   A CD1 1 
ATOM   1358 C CD2 . PHE   A 1 238 ? -37.01988 -15.61517 17.69260  1.000 76.14941  ? 856  PHE   A CD2 1 
ATOM   1359 C CE1 . PHE   A 1 238 ? -35.15124 -13.70563 17.00705  1.000 86.16850  ? 856  PHE   A CE1 1 
ATOM   1360 C CE2 . PHE   A 1 238 ? -35.99897 -15.29775 18.57355  1.000 81.86346  ? 856  PHE   A CE2 1 
ATOM   1361 C CZ  . PHE   A 1 238 ? -35.06445 -14.34064 18.23012  1.000 85.26333  ? 856  PHE   A CZ  1 
ATOM   1362 N N   . LEU   A 1 239 ? -39.59521 -17.75421 13.69602  1.000 61.45213  ? 857  LEU   A N   1 
ATOM   1363 C CA  . LEU   A 1 239 ? -40.57649 -18.26634 12.75502  1.000 58.82204  ? 857  LEU   A CA  1 
ATOM   1364 C C   . LEU   A 1 239 ? -41.83505 -18.72915 13.47516  1.000 55.53680  ? 857  LEU   A C   1 
ATOM   1365 O O   . LEU   A 1 239 ? -41.75818 -19.27377 14.58262  1.000 54.15221  ? 857  LEU   A O   1 
ATOM   1366 C CB  . LEU   A 1 239 ? -39.98850 -19.43339 11.94607  1.000 59.21625  ? 857  LEU   A CB  1 
ATOM   1367 C CG  . LEU   A 1 239 ? -38.80208 -19.10253 11.03768  1.000 65.45365  ? 857  LEU   A CG  1 
ATOM   1368 C CD1 . LEU   A 1 239 ? -38.20904 -20.37403 10.46070  1.000 65.82561  ? 857  LEU   A CD1 1 
ATOM   1369 C CD2 . LEU   A 1 239 ? -39.23360 -18.16240 9.92889   1.000 64.50369  ? 857  LEU   A CD2 1 
ATOM   1370 N N   . PRO   A 1 240 ? -43.00636 -18.53783 12.86474  1.000 54.30954  ? 858  PRO   A N   1 
ATOM   1371 C CA  . PRO   A 1 240 ? -44.27599 -19.02124 13.44338  1.000 51.97540  ? 858  PRO   A CA  1 
ATOM   1372 C C   . PRO   A 1 240 ? -44.44911 -20.52269 13.23415  1.000 52.77082  ? 858  PRO   A C   1 
ATOM   1373 O O   . PRO   A 1 240 ? -45.28850 -21.00185 12.46052  1.000 51.64201  ? 858  PRO   A O   1 
ATOM   1374 C CB  . PRO   A 1 240 ? -45.31148 -18.18423 12.68741  1.000 43.73440  ? 858  PRO   A CB  1 
ATOM   1375 C CG  . PRO   A 1 240 ? -44.69909 -18.01038 11.32932  1.000 47.96200  ? 858  PRO   A CG  1 
ATOM   1376 C CD  . PRO   A 1 240 ? -43.21258 -17.87389 11.56476  1.000 49.72612  ? 858  PRO   A CD  1 
ATOM   1377 N N   . VAL   A 1 241 ? -43.64792 -21.29651 13.97149  1.000 53.50814  ? 859  VAL   A N   1 
ATOM   1378 C CA  . VAL   A 1 241 ? -43.49376 -22.72209 13.68651  1.000 53.54374  ? 859  VAL   A CA  1 
ATOM   1379 C C   . VAL   A 1 241 ? -44.81805 -23.46136 13.84310  1.000 52.07401  ? 859  VAL   A C   1 
ATOM   1380 O O   . VAL   A 1 241 ? -45.19126 -24.27646 12.99119  1.000 53.09190  ? 859  VAL   A O   1 
ATOM   1381 C CB  . VAL   A 1 241 ? -42.39235 -23.32396 14.58174  1.000 57.85912  ? 859  VAL   A CB  1 
ATOM   1382 C CG1 . VAL   A 1 241 ? -42.39847 -24.84165 14.49428  1.000 57.73938  ? 859  VAL   A CG1 1 
ATOM   1383 C CG2 . VAL   A 1 241 ? -41.02932 -22.77531 14.18797  1.000 57.99984  ? 859  VAL   A CG2 1 
ATOM   1384 N N   . LYS   A 1 242 ? -45.55363 -23.18597 14.92214  1.000 49.63323  ? 860  LYS   A N   1 
ATOM   1385 C CA  . LYS   A 1 242 ? -46.80941 -23.88695 15.16940  1.000 55.06638  ? 860  LYS   A CA  1 
ATOM   1386 C C   . LYS   A 1 242 ? -47.85438 -23.64126 14.08933  1.000 52.77991  ? 860  LYS   A C   1 
ATOM   1387 O O   . LYS   A 1 242 ? -48.83535 -24.39026 14.02286  1.000 54.18913  ? 860  LYS   A O   1 
ATOM   1388 C CB  . LYS   A 1 242 ? -47.36899 -23.49160 16.53748  1.000 54.03077  ? 860  LYS   A CB  1 
ATOM   1389 C CG  . LYS   A 1 242 ? -46.64719 -24.13046 17.70731  1.000 54.29634  ? 860  LYS   A CG  1 
ATOM   1390 C CD  . LYS   A 1 242 ? -47.33963 -23.81190 19.01402  1.000 53.59933  ? 860  LYS   A CD  1 
ATOM   1391 C CE  . LYS   A 1 242 ? -46.84244 -24.71071 20.13406  1.000 59.48105  ? 860  LYS   A CE  1 
ATOM   1392 N NZ  . LYS   A 1 242 ? -47.64445 -24.52215 21.36956  1.000 64.15115  ? 860  LYS   A NZ  1 
ATOM   1393 N N   . TRP   A 1 243 ? -47.67132 -22.62457 13.25086  1.000 49.36991  ? 861  TRP   A N   1 
ATOM   1394 C CA  . TRP   A 1 243 ? -48.56458 -22.35087 12.13509  1.000 47.40176  ? 861  TRP   A CA  1 
ATOM   1395 C C   . TRP   A 1 243 ? -48.03737 -22.86447 10.80679  1.000 51.74156  ? 861  TRP   A C   1 
ATOM   1396 O O   . TRP   A 1 243 ? -48.74536 -22.76669 9.79574   1.000 49.68561  ? 861  TRP   A O   1 
ATOM   1397 C CB  . TRP   A 1 243 ? -48.82446 -20.84553 12.02489  1.000 48.98531  ? 861  TRP   A CB  1 
ATOM   1398 C CG  . TRP   A 1 243 ? -49.78937 -20.35324 13.02535  1.000 48.36932  ? 861  TRP   A CG  1 
ATOM   1399 C CD1 . TRP   A 1 243 ? -51.11751 -20.12790 12.83776  1.000 48.60626  ? 861  TRP   A CD1 1 
ATOM   1400 C CD2 . TRP   A 1 243 ? -49.51443 -20.04051 14.39318  1.000 49.29875  ? 861  TRP   A CD2 1 
ATOM   1401 N NE1 . TRP   A 1 243 ? -51.69093 -19.68887 14.00741  1.000 44.95013  ? 861  TRP   A NE1 1 
ATOM   1402 C CE2 . TRP   A 1 243 ? -50.72416 -19.62386 14.97639  1.000 47.50959  ? 861  TRP   A CE2 1 
ATOM   1403 C CE3 . TRP   A 1 243 ? -48.35957 -20.06728 15.18120  1.000 52.76373  ? 861  TRP   A CE3 1 
ATOM   1404 C CZ2 . TRP   A 1 243 ? -50.81377 -19.23624 16.31210  1.000 50.75701  ? 861  TRP   A CZ2 1 
ATOM   1405 C CZ3 . TRP   A 1 243 ? -48.44963 -19.67772 16.50679  1.000 55.36127  ? 861  TRP   A CZ3 1 
ATOM   1406 C CH2 . TRP   A 1 243 ? -49.66751 -19.26852 17.05848  1.000 55.63086  ? 861  TRP   A CH2 1 
ATOM   1407 N N   . MET   A 1 244 ? -46.82591 -23.40847 10.78284  1.000 51.71235  ? 862  MET   A N   1 
ATOM   1408 C CA  . MET   A 1 244 ? -46.15258 -23.72572 9.53542   1.000 54.07049  ? 862  MET   A CA  1 
ATOM   1409 C C   . MET   A 1 244 ? -46.38840 -25.16934 9.11321   1.000 53.36411  ? 862  MET   A C   1 
ATOM   1410 O O   . MET   A 1 244 ? -46.51092 -26.07080 9.94461   1.000 55.05252  ? 862  MET   A O   1 
ATOM   1411 C CB  . MET   A 1 244 ? -44.65358 -23.45106 9.65743   1.000 54.45265  ? 862  MET   A CB  1 
ATOM   1412 C CG  . MET   A 1 244 ? -44.30963 -21.96833 9.65274   1.000 51.91090  ? 862  MET   A CG  1 
ATOM   1413 S SD  . MET   A 1 244 ? -42.60234 -21.60810 10.09435  1.000 58.98759  ? 862  MET   A SD  1 
ATOM   1414 C CE  . MET   A 1 244 ? -41.73219 -22.43169 8.77197   1.000 61.14923  ? 862  MET   A CE  1 
ATOM   1415 N N   . ALA   A 1 245 ? -46.45302 -25.37150 7.79990   1.000 51.90189  ? 863  ALA   A N   1 
ATOM   1416 C CA  . ALA   A 1 245 ? -46.52088 -26.69467 7.20807   1.000 55.35568  ? 863  ALA   A CA  1 
ATOM   1417 C C   . ALA   A 1 245 ? -45.16698 -27.39230 7.31352   1.000 60.56704  ? 863  ALA   A C   1 
ATOM   1418 O O   . ALA   A 1 245 ? -44.12468 -26.73331 7.32737   1.000 60.68504  ? 863  ALA   A O   1 
ATOM   1419 C CB  . ALA   A 1 245 ? -46.94631 -26.60252 5.74593   1.000 54.21650  ? 863  ALA   A CB  1 
ATOM   1420 N N   . PRO   A 1 246 ? -45.16126 -28.72789 7.40126   1.000 59.21412  ? 864  PRO   A N   1 
ATOM   1421 C CA  . PRO   A 1 246 ? -43.87920 -29.44028 7.53636   1.000 58.80772  ? 864  PRO   A CA  1 
ATOM   1422 C C   . PRO   A 1 246 ? -42.88654 -29.12447 6.43268   1.000 56.24461  ? 864  PRO   A C   1 
ATOM   1423 O O   . PRO   A 1 246 ? -41.69614 -28.93631 6.71634   1.000 58.32802  ? 864  PRO   A O   1 
ATOM   1424 C CB  . PRO   A 1 246 ? -44.30210 -30.91600 7.51870   1.000 60.74226  ? 864  PRO   A CB  1 
ATOM   1425 C CG  . PRO   A 1 246 ? -45.71582 -30.90637 8.01071   1.000 61.37394  ? 864  PRO   A CG  1 
ATOM   1426 C CD  . PRO   A 1 246 ? -46.31327 -29.64496 7.47311   1.000 61.27336  ? 864  PRO   A CD  1 
ATOM   1427 N N   . GLU   A 1 247 ? -43.34145 -29.05247 5.17745   1.000 54.23757  ? 865  GLU   A N   1 
ATOM   1428 C CA  . GLU   A 1 247 ? -42.43609 -28.71213 4.08392   1.000 57.41636  ? 865  GLU   A CA  1 
ATOM   1429 C C   . GLU   A 1 247 ? -41.84705 -27.31931 4.24215   1.000 61.69836  ? 865  GLU   A C   1 
ATOM   1430 O O   . GLU   A 1 247 ? -40.75316 -27.06159 3.72803   1.000 60.80737  ? 865  GLU   A O   1 
ATOM   1431 C CB  . GLU   A 1 247 ? -43.14967 -28.83226 2.73215   1.000 57.49972  ? 865  GLU   A CB  1 
ATOM   1432 C CG  . GLU   A 1 247 ? -44.16874 -27.73820 2.42600   1.000 62.29154  ? 865  GLU   A CG  1 
ATOM   1433 C CD  . GLU   A 1 247 ? -45.58061 -28.11523 2.82743   1.000 62.49303  ? 865  GLU   A CD  1 
ATOM   1434 O OE1 . GLU   A 1 247 ? -45.73328 -29.05185 3.63779   1.000 60.65719  ? 865  GLU   A OE1 1 
ATOM   1435 O OE2 . GLU   A 1 247 ? -46.53639 -27.48293 2.32500   1.000 63.03995  ? 865  GLU   A OE2 1 
ATOM   1436 N N   . SER   A 1 248 ? -42.53821 -26.42492 4.95155   1.000 57.33540  ? 866  SER   A N   1 
ATOM   1437 C CA  . SER   A 1 248 ? -41.98047 -25.10872 5.23142   1.000 59.15745  ? 866  SER   A CA  1 
ATOM   1438 C C   . SER   A 1 248 ? -40.91898 -25.17926 6.32075   1.000 56.89477  ? 866  SER   A C   1 
ATOM   1439 O O   . SER   A 1 248 ? -39.83712 -24.59811 6.18063   1.000 57.94679  ? 866  SER   A O   1 
ATOM   1440 C CB  . SER   A 1 248 ? -43.09483 -24.14361 5.63241   1.000 59.79882  ? 866  SER   A CB  1 
ATOM   1441 O OG  . SER   A 1 248 ? -44.03012 -23.99499 4.58417   1.000 58.33195  ? 866  SER   A OG  1 
ATOM   1442 N N   . ILE   A 1 249 ? -41.21186 -25.89485 7.40928   1.000 56.85893  ? 867  ILE   A N   1 
ATOM   1443 C CA  . ILE   A 1 249 ? -40.26352 -26.00192 8.51707   1.000 57.59942  ? 867  ILE   A CA  1 
ATOM   1444 C C   . ILE   A 1 249 ? -38.99713 -26.71503 8.06328   1.000 64.06773  ? 867  ILE   A C   1 
ATOM   1445 O O   . ILE   A 1 249 ? -37.89274 -26.16096 8.11236   1.000 71.38684  ? 867  ILE   A O   1 
ATOM   1446 C CB  . ILE   A 1 249 ? -40.90396 -26.73312 9.71013   1.000 56.20627  ? 867  ILE   A CB  1 
ATOM   1447 C CG1 . ILE   A 1 249 ? -42.18471 -26.04026 10.16515  1.000 51.76939  ? 867  ILE   A CG1 1 
ATOM   1448 C CG2 . ILE   A 1 249 ? -39.92861 -26.82103 10.86963  1.000 54.91447  ? 867  ILE   A CG2 1 
ATOM   1449 C CD1 . ILE   A 1 249 ? -42.92634 -26.81117 11.23743  1.000 52.26636  ? 867  ILE   A CD1 1 
ATOM   1450 N N   . PHE   A 1 250 ? -39.14703 -27.95419 7.60001   1.000 65.59984  ? 868  PHE   A N   1 
ATOM   1451 C CA  . PHE   A 1 250 ? -38.00813 -28.83594 7.38855   1.000 67.27371  ? 868  PHE   A CA  1 
ATOM   1452 C C   . PHE   A 1 250 ? -37.40280 -28.72692 5.99720   1.000 69.98034  ? 868  PHE   A C   1 
ATOM   1453 O O   . PHE   A 1 250 ? -36.19584 -28.94503 5.84555   1.000 80.52562  ? 868  PHE   A O   1 
ATOM   1454 C CB  . PHE   A 1 250 ? -38.42266 -30.28306 7.66766   1.000 65.25993  ? 868  PHE   A CB  1 
ATOM   1455 C CG  . PHE   A 1 250 ? -39.19909 -30.44605 8.94432   1.000 61.27557  ? 868  PHE   A CG  1 
ATOM   1456 C CD1 . PHE   A 1 250 ? -38.57440 -30.28684 10.16895  1.000 63.10665  ? 868  PHE   A CD1 1 
ATOM   1457 C CD2 . PHE   A 1 250 ? -40.55734 -30.73738 8.92042   1.000 57.20453  ? 868  PHE   A CD2 1 
ATOM   1458 C CE1 . PHE   A 1 250 ? -39.28227 -30.42205 11.34762  1.000 64.64345  ? 868  PHE   A CE1 1 
ATOM   1459 C CE2 . PHE   A 1 250 ? -41.27235 -30.87628 10.09497  1.000 57.39701  ? 868  PHE   A CE2 1 
ATOM   1460 C CZ  . PHE   A 1 250 ? -40.63468 -30.72046 11.30931  1.000 61.98609  ? 868  PHE   A CZ  1 
ATOM   1461 N N   . ASP   A 1 251 ? -38.19519 -28.38935 4.97991   1.000 67.98361  ? 869  ASP   A N   1 
ATOM   1462 C CA  . ASP   A 1 251 ? -37.69341 -28.32074 3.61357   1.000 72.44710  ? 869  ASP   A CA  1 
ATOM   1463 C C   . ASP   A 1 251 ? -37.77736 -26.92778 2.99989   1.000 73.19094  ? 869  ASP   A C   1 
ATOM   1464 O O   . ASP   A 1 251 ? -37.46091 -26.77384 1.81506   1.000 75.61287  ? 869  ASP   A O   1 
ATOM   1465 C CB  . ASP   A 1 251 ? -38.43755 -29.32998 2.72757   1.000 72.59002  ? 869  ASP   A CB  1 
ATOM   1466 C CG  . ASP   A 1 251 ? -38.20069 -30.76242 3.15980   1.000 73.18562  ? 869  ASP   A CG  1 
ATOM   1467 O OD1 . ASP   A 1 251 ? -37.03531 -31.21241 3.11275   1.000 74.74144  ? 869  ASP   A OD1 1 
ATOM   1468 O OD2 . ASP   A 1 251 ? -39.17242 -31.43133 3.56512   1.000 69.99040  ? 869  ASP   A OD2 1 
ATOM   1469 N N   . ASN   A 1 252 ? -38.19853 -25.91668 3.76480   1.000 73.35523  ? 870  ASN   A N   1 
ATOM   1470 C CA  . ASN   A 1 252 ? -38.12627 -24.50999 3.35422   1.000 75.67461  ? 870  ASN   A CA  1 
ATOM   1471 C C   . ASN   A 1 252 ? -38.94407 -24.23315 2.09194   1.000 74.02215  ? 870  ASN   A C   1 
ATOM   1472 O O   . ASN   A 1 252 ? -38.57050 -23.41013 1.25480   1.000 76.70861  ? 870  ASN   A O   1 
ATOM   1473 C CB  . ASN   A 1 252 ? -36.67250 -24.06552 3.16812   1.000 81.59779  ? 870  ASN   A CB  1 
ATOM   1474 C CG  . ASN   A 1 252 ? -36.51362 -22.55931 3.23594   1.000 84.35713  ? 870  ASN   A CG  1 
ATOM   1475 O OD1 . ASN   A 1 252 ? -37.11916 -21.89894 4.07927   1.000 81.26413  ? 870  ASN   A OD1 1 
ATOM   1476 N ND2 . ASN   A 1 252 ? -35.70761 -22.00569 2.33504   1.000 89.52121  ? 870  ASN   A ND2 1 
ATOM   1477 N N   . LEU   A 1 253 ? -40.07966 -24.90875 1.96257   1.000 70.36308  ? 871  LEU   A N   1 
ATOM   1478 C CA  . LEU   A 1 253 ? -40.97696 -24.72847 0.82945   1.000 68.45215  ? 871  LEU   A CA  1 
ATOM   1479 C C   . LEU   A 1 253 ? -42.19309 -23.92704 1.27608   1.000 65.98254  ? 871  LEU   A C   1 
ATOM   1480 O O   . LEU   A 1 253 ? -42.89413 -24.32566 2.21101   1.000 64.69784  ? 871  LEU   A O   1 
ATOM   1481 C CB  . LEU   A 1 253 ? -41.40501 -26.07939 0.25453   1.000 65.37870  ? 871  LEU   A CB  1 
ATOM   1482 N N   . TYR   A 1 254 ? -42.42814 -22.79325 0.61687   1.000 68.82750  ? 872  TYR   A N   1 
ATOM   1483 C CA  . TYR   A 1 254 ? -43.52060 -21.87873 0.94253   1.000 65.59363  ? 872  TYR   A CA  1 
ATOM   1484 C C   . TYR   A 1 254 ? -44.41164 -21.72460 -0.28300  1.000 66.26674  ? 872  TYR   A C   1 
ATOM   1485 O O   . TYR   A 1 254 ? -44.00329 -21.11553 -1.27808  1.000 69.84916  ? 872  TYR   A O   1 
ATOM   1486 C CB  . TYR   A 1 254 ? -42.98761 -20.51352 1.37894   1.000 66.70132  ? 872  TYR   A CB  1 
ATOM   1487 C CG  . TYR   A 1 254 ? -42.37210 -20.46609 2.75762   1.000 69.04582  ? 872  TYR   A CG  1 
ATOM   1488 C CD1 . TYR   A 1 254 ? -41.01346 -20.68253 2.94060   1.000 74.60802  ? 872  TYR   A CD1 1 
ATOM   1489 C CD2 . TYR   A 1 254 ? -43.14516 -20.17479 3.87399   1.000 64.13094  ? 872  TYR   A CD2 1 
ATOM   1490 C CE1 . TYR   A 1 254 ? -40.44229 -20.62364 4.19840   1.000 74.39511  ? 872  TYR   A CE1 1 
ATOM   1491 C CE2 . TYR   A 1 254 ? -42.58422 -20.11782 5.14113   1.000 63.51242  ? 872  TYR   A CE2 1 
ATOM   1492 C CZ  . TYR   A 1 254 ? -41.22935 -20.34396 5.29799   1.000 71.35639  ? 872  TYR   A CZ  1 
ATOM   1493 O OH  . TYR   A 1 254 ? -40.65074 -20.29026 6.54751   1.000 74.83528  ? 872  TYR   A OH  1 
ATOM   1494 N N   . THR   A 1 255 ? -45.62701 -22.26307 -0.21393  1.000 64.04259  ? 873  THR   A N   1 
ATOM   1495 C CA  . THR   A 1 255 ? -46.59523 -22.14057 -1.29703  1.000 65.80722  ? 873  THR   A CA  1 
ATOM   1496 C C   . THR   A 1 255 ? -47.94900 -21.73178 -0.72999  1.000 62.10051  ? 873  THR   A C   1 
ATOM   1497 O O   . THR   A 1 255 ? -48.14069 -21.65561 0.48535   1.000 57.28647  ? 873  THR   A O   1 
ATOM   1498 C CB  . THR   A 1 255 ? -46.72804 -23.45265 -2.09040  1.000 66.72815  ? 873  THR   A CB  1 
ATOM   1499 O OG1 . THR   A 1 255 ? -47.17521 -24.49681 -1.21998  1.000 67.77064  ? 873  THR   A OG1 1 
ATOM   1500 C CG2 . THR   A 1 255 ? -45.39647 -23.85418 -2.70782  1.000 68.98056  ? 873  THR   A CG2 1 
ATOM   1501 N N   . THR   A 1 256 ? -48.89047 -21.45375 -1.63701  1.000 58.84698  ? 874  THR   A N   1 
ATOM   1502 C CA  . THR   A 1 256 ? -50.28751 -21.31332 -1.24028  1.000 60.68191  ? 874  THR   A CA  1 
ATOM   1503 C C   . THR   A 1 256 ? -50.74480 -22.53643 -0.45654  1.000 61.97246  ? 874  THR   A C   1 
ATOM   1504 O O   . THR   A 1 256 ? -51.52515 -22.42265 0.49660   1.000 62.09238  ? 874  THR   A O   1 
ATOM   1505 C CB  . THR   A 1 256 ? -51.17275 -21.10739 -2.47596  1.000 65.48374  ? 874  THR   A CB  1 
ATOM   1506 O OG1 . THR   A 1 256 ? -50.84020 -19.86691 -3.11039  1.000 68.67258  ? 874  THR   A OG1 1 
ATOM   1507 C CG2 . THR   A 1 256 ? -52.65193 -21.10063 -2.09627  1.000 63.38378  ? 874  THR   A CG2 1 
ATOM   1508 N N   . LEU   A 1 257 ? -50.24017 -23.71723 -0.82679  1.000 58.91649  ? 875  LEU   A N   1 
ATOM   1509 C CA  . LEU   A 1 257 ? -50.60560 -24.93581 -0.11407  1.000 56.58704  ? 875  LEU   A CA  1 
ATOM   1510 C C   . LEU   A 1 257 ? -50.06623 -24.94699 1.31143   1.000 54.78489  ? 875  LEU   A C   1 
ATOM   1511 O O   . LEU   A 1 257 ? -50.68203 -25.55156 2.19818   1.000 53.11093  ? 875  LEU   A O   1 
ATOM   1512 C CB  . LEU   A 1 257 ? -50.11807 -26.15715 -0.88919  1.000 59.47494  ? 875  LEU   A CB  1 
ATOM   1513 C CG  . LEU   A 1 257 ? -50.83284 -26.36691 -2.22499  1.000 65.63473  ? 875  LEU   A CG  1 
ATOM   1514 C CD1 . LEU   A 1 257 ? -50.29770 -27.59739 -2.94370  1.000 69.26543  ? 875  LEU   A CD1 1 
ATOM   1515 C CD2 . LEU   A 1 257 ? -52.33873 -26.47158 -2.02088  1.000 64.70140  ? 875  LEU   A CD2 1 
ATOM   1516 N N   . SER   A 1 258 ? -48.92811 -24.29558 1.55967   1.000 54.95683  ? 876  SER   A N   1 
ATOM   1517 C CA  . SER   A 1 258 ? -48.49150 -24.13620 2.94294   1.000 53.44601  ? 876  SER   A CA  1 
ATOM   1518 C C   . SER   A 1 258 ? -49.34335 -23.10538 3.67067   1.000 51.79970  ? 876  SER   A C   1 
ATOM   1519 O O   . SER   A 1 258 ? -49.57855 -23.23790 4.87731   1.000 52.50427  ? 876  SER   A O   1 
ATOM   1520 C CB  . SER   A 1 258 ? -47.00851 -23.76253 2.99343   1.000 57.38894  ? 876  SER   A CB  1 
ATOM   1521 O OG  . SER   A 1 258 ? -46.67760 -22.82295 1.98505   1.000 63.88227  ? 876  SER   A OG  1 
ATOM   1522 N N   . ASP   A 1 259 ? -49.82169 -22.08402 2.95330   1.000 48.29015  ? 877  ASP   A N   1 
ATOM   1523 C CA  . ASP   A 1 259 ? -50.80740 -21.17019 3.52640   1.000 49.33837  ? 877  ASP   A CA  1 
ATOM   1524 C C   . ASP   A 1 259 ? -52.07118 -21.91587 3.93966   1.000 50.91701  ? 877  ASP   A C   1 
ATOM   1525 O O   . ASP   A 1 259 ? -52.68915 -21.59247 4.95959   1.000 46.56686  ? 877  ASP   A O   1 
ATOM   1526 C CB  . ASP   A 1 259 ? -51.14897 -20.06128 2.52643   1.000 51.90535  ? 877  ASP   A CB  1 
ATOM   1527 C CG  . ASP   A 1 259 ? -50.13191 -18.94316 2.51947   1.000 56.87739  ? 877  ASP   A CG  1 
ATOM   1528 O OD1 . ASP   A 1 259 ? -49.25558 -18.93709 3.40360   1.000 53.72459  ? 877  ASP   A OD1 1 
ATOM   1529 O OD2 . ASP   A 1 259 ? -50.21088 -18.07097 1.62737   1.000 53.79510  ? 877  ASP   A OD2 1 
ATOM   1530 N N   . VAL   A 1 260 ? -52.46400 -22.92501 3.16093   1.000 49.04050  ? 878  VAL   A N   1 
ATOM   1531 C CA  . VAL   A 1 260 ? -53.65782 -23.70051 3.48108   1.000 45.03480  ? 878  VAL   A CA  1 
ATOM   1532 C C   . VAL   A 1 260 ? -53.46916 -24.44978 4.79428   1.000 53.76031  ? 878  VAL   A C   1 
ATOM   1533 O O   . VAL   A 1 260 ? -54.40439 -24.56856 5.59771   1.000 59.30386  ? 878  VAL   A O   1 
ATOM   1534 C CB  . VAL   A 1 260 ? -54.00588 -24.64925 2.31708   1.000 49.83264  ? 878  VAL   A CB  1 
ATOM   1535 C CG1 . VAL   A 1 260 ? -55.02684 -25.68010 2.75560   1.000 52.05220  ? 878  VAL   A CG1 1 
ATOM   1536 C CG2 . VAL   A 1 260 ? -54.52820 -23.85122 1.13655   1.000 48.12178  ? 878  VAL   A CG2 1 
ATOM   1537 N N   . TRP   A 1 261 ? -52.26487 -24.97713 5.03074   1.000 53.77427  ? 879  TRP   A N   1 
ATOM   1538 C CA  . TRP   A 1 261 ? -51.96505 -25.56377 6.33328   1.000 51.74141  ? 879  TRP   A CA  1 
ATOM   1539 C C   . TRP   A 1 261 ? -52.15629 -24.53396 7.44008   1.000 46.50396  ? 879  TRP   A C   1 
ATOM   1540 O O   . TRP   A 1 261 ? -52.81026 -24.80609 8.45449   1.000 50.61187  ? 879  TRP   A O   1 
ATOM   1541 C CB  . TRP   A 1 261 ? -50.53622 -26.11572 6.35732   1.000 51.69167  ? 879  TRP   A CB  1 
ATOM   1542 C CG  . TRP   A 1 261 ? -50.13650 -26.71033 7.69075   1.000 53.76611  ? 879  TRP   A CG  1 
ATOM   1543 C CD1 . TRP   A 1 261 ? -49.92284 -26.03808 8.86209   1.000 50.95926  ? 879  TRP   A CD1 1 
ATOM   1544 C CD2 . TRP   A 1 261 ? -49.88925 -28.09517 7.97752   1.000 54.36315  ? 879  TRP   A CD2 1 
ATOM   1545 N NE1 . TRP   A 1 261 ? -49.57332 -26.91765 9.85849   1.000 50.08422  ? 879  TRP   A NE1 1 
ATOM   1546 C CE2 . TRP   A 1 261 ? -49.54116 -28.18525 9.34116   1.000 51.98673  ? 879  TRP   A CE2 1 
ATOM   1547 C CE3 . TRP   A 1 261 ? -49.93355 -29.26674 7.21534   1.000 58.14996  ? 879  TRP   A CE3 1 
ATOM   1548 C CZ2 . TRP   A 1 261 ? -49.24005 -29.39884 9.95781   1.000 52.76093  ? 879  TRP   A CZ2 1 
ATOM   1549 C CZ3 . TRP   A 1 261 ? -49.63613 -30.47453 7.83305   1.000 59.21570  ? 879  TRP   A CZ3 1 
ATOM   1550 C CH2 . TRP   A 1 261 ? -49.29558 -30.52900 9.18796   1.000 57.11722  ? 879  TRP   A CH2 1 
ATOM   1551 N N   . SER   A 1 262 ? -51.58658 -23.33840 7.25703   1.000 42.02171  ? 880  SER   A N   1 
ATOM   1552 C CA  . SER   A 1 262 ? -51.72283 -22.28086 8.25465   1.000 48.32051  ? 880  SER   A CA  1 
ATOM   1553 C C   . SER   A 1 262 ? -53.18008 -21.89238 8.45758   1.000 46.87314  ? 880  SER   A C   1 
ATOM   1554 O O   . SER   A 1 262 ? -53.59805 -21.58210 9.57932   1.000 44.24227  ? 880  SER   A O   1 
ATOM   1555 C CB  . SER   A 1 262 ? -50.89596 -21.06433 7.83619   1.000 51.05868  ? 880  SER   A CB  1 
ATOM   1556 O OG  . SER   A 1 262 ? -49.51658 -21.38651 7.77834   1.000 56.14972  ? 880  SER   A OG  1 
ATOM   1557 N N   . TYR   A 1 263 ? -53.96750 -21.90554 7.38195   1.000 43.89807  ? 881  TYR   A N   1 
ATOM   1558 C CA  . TYR   A 1 263 ? -55.39606 -21.62866 7.49904   1.000 44.35629  ? 881  TYR   A CA  1 
ATOM   1559 C C   . TYR   A 1 263 ? -56.08007 -22.63897 8.41222   1.000 49.51054  ? 881  TYR   A C   1 
ATOM   1560 O O   . TYR   A 1 263 ? -56.94982 -22.27632 9.21442   1.000 46.87031  ? 881  TYR   A O   1 
ATOM   1561 C CB  . TYR   A 1 263 ? -56.03276 -21.62925 6.10621   1.000 44.75902  ? 881  TYR   A CB  1 
ATOM   1562 C CG  . TYR   A 1 263 ? -57.53861 -21.51487 6.07244   1.000 48.03335  ? 881  TYR   A CG  1 
ATOM   1563 C CD1 . TYR   A 1 263 ? -58.16717 -20.27457 6.11012   1.000 47.85520  ? 881  TYR   A CD1 1 
ATOM   1564 C CD2 . TYR   A 1 263 ? -58.33291 -22.65060 5.97491   1.000 48.84846  ? 881  TYR   A CD2 1 
ATOM   1565 C CE1 . TYR   A 1 263 ? -59.54690 -20.17369 6.06801   1.000 48.90137  ? 881  TYR   A CE1 1 
ATOM   1566 C CE2 . TYR   A 1 263 ? -59.70819 -22.55706 5.92760   1.000 48.80000  ? 881  TYR   A CE2 1 
ATOM   1567 C CZ  . TYR   A 1 263 ? -60.31152 -21.31610 5.97431   1.000 50.83559  ? 881  TYR   A CZ  1 
ATOM   1568 O OH  . TYR   A 1 263 ? -61.68125 -21.22287 5.92223   1.000 45.45793  ? 881  TYR   A OH  1 
ATOM   1569 N N   . GLY   A 1 264 ? -55.69503 -23.91218 8.30648   1.000 46.82609  ? 882  GLY   A N   1 
ATOM   1570 C CA  . GLY   A 1 264 ? -56.22246 -24.91375 9.21932   1.000 45.90043  ? 882  GLY   A CA  1 
ATOM   1571 C C   . GLY   A 1 264 ? -55.87686 -24.61324 10.66470  1.000 48.94804  ? 882  GLY   A C   1 
ATOM   1572 O O   . GLY   A 1 264 ? -56.71547 -24.76097 11.55890  1.000 51.30024  ? 882  GLY   A O   1 
ATOM   1573 N N   . ILE   A 1 265 ? -54.63364 -24.18821 10.91271  1.000 48.15593  ? 883  ILE   A N   1 
ATOM   1574 C CA  . ILE   A 1 265 ? -54.23959 -23.76575 12.25507  1.000 46.85757  ? 883  ILE   A CA  1 
ATOM   1575 C C   . ILE   A 1 265 ? -55.04799 -22.55094 12.68306  1.000 47.35201  ? 883  ILE   A C   1 
ATOM   1576 O O   . ILE   A 1 265 ? -55.47542 -22.44342 13.84045  1.000 48.19573  ? 883  ILE   A O   1 
ATOM   1577 C CB  . ILE   A 1 265 ? -52.72796 -23.47632 12.30833  1.000 45.61145  ? 883  ILE   A CB  1 
ATOM   1578 C CG1 . ILE   A 1 265 ? -51.92514 -24.69296 11.83781  1.000 45.08826  ? 883  ILE   A CG1 1 
ATOM   1579 C CG2 . ILE   A 1 265 ? -52.30438 -23.11190 13.71990  1.000 46.50129  ? 883  ILE   A CG2 1 
ATOM   1580 C CD1 . ILE   A 1 265 ? -52.04005 -25.88900 12.76432  1.000 43.73336  ? 883  ILE   A CD1 1 
ATOM   1581 N N   . LEU   A 1 266 ? -55.27060 -21.61792 11.75327  1.000 46.09310  ? 884  LEU   A N   1 
ATOM   1582 C CA  . LEU   A 1 266 ? -56.10084 -20.45459 12.04584  1.000 46.80810  ? 884  LEU   A CA  1 
ATOM   1583 C C   . LEU   A 1 266 ? -57.51876 -20.86789 12.41424  1.000 46.43646  ? 884  LEU   A C   1 
ATOM   1584 O O   . LEU   A 1 266 ? -58.11158 -20.30416 13.33893  1.000 44.59493  ? 884  LEU   A O   1 
ATOM   1585 C CB  . LEU   A 1 266 ? -56.10485 -19.49689 10.85121  1.000 49.88596  ? 884  LEU   A CB  1 
ATOM   1586 C CG  . LEU   A 1 266 ? -57.19315 -18.43050 10.75581  1.000 50.76366  ? 884  LEU   A CG  1 
ATOM   1587 C CD1 . LEU   A 1 266 ? -57.20702 -17.54514 11.97847  1.000 48.45767  ? 884  LEU   A CD1 1 
ATOM   1588 C CD2 . LEU   A 1 266 ? -56.98480 -17.61410 9.50870   1.000 57.05943  ? 884  LEU   A CD2 1 
ATOM   1589 N N   . LEU   A 1 267 ? -58.07984 -21.85424 11.71095  1.000 44.06346  ? 885  LEU   A N   1 
ATOM   1590 C CA  . LEU   A 1 267 ? -59.41336 -22.32897 12.06597  1.000 47.35028  ? 885  LEU   A CA  1 
ATOM   1591 C C   . LEU   A 1 267 ? -59.43897 -22.88473 13.48245  1.000 52.88835  ? 885  LEU   A C   1 
ATOM   1592 O O   . LEU   A 1 267 ? -60.40824 -22.67504 14.21974  1.000 52.00665  ? 885  LEU   A O   1 
ATOM   1593 C CB  . LEU   A 1 267 ? -59.89341 -23.38204 11.06734  1.000 51.01277  ? 885  LEU   A CB  1 
ATOM   1594 C CG  . LEU   A 1 267 ? -60.14095 -22.90827 9.63989   1.000 50.47076  ? 885  LEU   A CG  1 
ATOM   1595 C CD1 . LEU   A 1 267 ? -61.18771 -23.79278 8.96638   1.000 45.42019  ? 885  LEU   A CD1 1 
ATOM   1596 C CD2 . LEU   A 1 267 ? -60.56520 -21.43831 9.59842   1.000 48.56983  ? 885  LEU   A CD2 1 
ATOM   1597 N N   . TRP   A 1 268 ? -58.37707 -23.58614 13.88461  1.000 51.53537  ? 886  TRP   A N   1 
ATOM   1598 C CA  . TRP   A 1 268 ? -58.29310 -24.08166 15.25488  1.000 49.44058  ? 886  TRP   A CA  1 
ATOM   1599 C C   . TRP   A 1 268 ? -58.25736 -22.92864 16.24917  1.000 49.71692  ? 886  TRP   A C   1 
ATOM   1600 O O   . TRP   A 1 268 ? -58.87006 -22.99990 17.32292  1.000 51.27821  ? 886  TRP   A O   1 
ATOM   1601 C CB  . TRP   A 1 268 ? -57.05862 -24.96973 15.41908  1.000 47.42610  ? 886  TRP   A CB  1 
ATOM   1602 C CG  . TRP   A 1 268 ? -57.06759 -25.74387 16.69602  1.000 46.62281  ? 886  TRP   A CG  1 
ATOM   1603 C CD1 . TRP   A 1 268 ? -57.47377 -27.03280 16.86446  1.000 45.75577  ? 886  TRP   A CD1 1 
ATOM   1604 C CD2 . TRP   A 1 268 ? -56.64788 -25.28166 17.98978  1.000 49.58548  ? 886  TRP   A CD2 1 
ATOM   1605 N NE1 . TRP   A 1 268 ? -57.33965 -27.40139 18.18285  1.000 50.66975  ? 886  TRP   A NE1 1 
ATOM   1606 C CE2 . TRP   A 1 268 ? -56.83668 -26.34398 18.89313  1.000 51.29273  ? 886  TRP   A CE2 1 
ATOM   1607 C CE3 . TRP   A 1 268 ? -56.13212 -24.07373 18.47023  1.000 48.79302  ? 886  TRP   A CE3 1 
ATOM   1608 C CZ2 . TRP   A 1 268 ? -56.53049 -26.23580 20.24733  1.000 52.59970  ? 886  TRP   A CZ2 1 
ATOM   1609 C CZ3 . TRP   A 1 268 ? -55.83271 -23.96713 19.82090  1.000 50.80061  ? 886  TRP   A CZ3 1 
ATOM   1610 C CH2 . TRP   A 1 268 ? -56.02777 -25.04045 20.68783  1.000 53.79388  ? 886  TRP   A CH2 1 
ATOM   1611 N N   . GLU   A 1 269 ? -57.54162 -21.85576 15.90307  1.000 47.93211  ? 887  GLU   A N   1 
ATOM   1612 C CA  . GLU   A 1 269 ? -57.55700 -20.64744 16.72016  1.000 53.24611  ? 887  GLU   A CA  1 
ATOM   1613 C C   . GLU   A 1 269 ? -58.96880 -20.10240 16.87954  1.000 54.18633  ? 887  GLU   A C   1 
ATOM   1614 O O   . GLU   A 1 269 ? -59.38090 -19.73505 17.98718  1.000 53.25472  ? 887  GLU   A O   1 
ATOM   1615 C CB  . GLU   A 1 269 ? -56.65599 -19.58466 16.09462  1.000 52.40443  ? 887  GLU   A CB  1 
ATOM   1616 C CG  . GLU   A 1 269 ? -55.17448 -19.75497 16.35792  1.000 51.38048  ? 887  GLU   A CG  1 
ATOM   1617 C CD  . GLU   A 1 269 ? -54.36951 -18.57336 15.83986  1.000 50.72578  ? 887  GLU   A CD  1 
ATOM   1618 O OE1 . GLU   A 1 269 ? -54.19223 -18.45884 14.61052  1.000 50.13383  ? 887  GLU   A OE1 1 
ATOM   1619 O OE2 . GLU   A 1 269 ? -53.93589 -17.74557 16.66931  1.000 51.39200  ? 887  GLU   A OE2 1 
ATOM   1620 N N   . ILE   A 1 270 ? -59.72199 -20.03963 15.78030  1.000 48.06615  ? 888  ILE   A N   1 
ATOM   1621 C CA  . ILE   A 1 270 ? -61.05252 -19.43914 15.81763  1.000 45.90361  ? 888  ILE   A CA  1 
ATOM   1622 C C   . ILE   A 1 270 ? -61.98535 -20.25366 16.70224  1.000 49.58374  ? 888  ILE   A C   1 
ATOM   1623 O O   . ILE   A 1 270 ? -62.64163 -19.71833 17.60557  1.000 50.26728  ? 888  ILE   A O   1 
ATOM   1624 C CB  . ILE   A 1 270 ? -61.61271 -19.29190 14.39166  1.000 44.51936  ? 888  ILE   A CB  1 
ATOM   1625 C CG1 . ILE   A 1 270 ? -60.85037 -18.20114 13.63280  1.000 42.35109  ? 888  ILE   A CG1 1 
ATOM   1626 C CG2 . ILE   A 1 270 ? -63.10664 -19.00557 14.42339  1.000 48.17154  ? 888  ILE   A CG2 1 
ATOM   1627 C CD1 . ILE   A 1 270 ? -61.28710 -18.04147 12.19126  1.000 46.57286  ? 888  ILE   A CD1 1 
ATOM   1628 N N   . PHE   A 1 271 ? -62.05696 -21.55648 16.45933  1.000 48.45018  ? 889  PHE   A N   1 
ATOM   1629 C CA  . PHE   A 1 271 ? -63.04290 -22.39639 17.12199  1.000 55.66094  ? 889  PHE   A CA  1 
ATOM   1630 C C   . PHE   A 1 271 ? -62.58938 -22.89103 18.48719  1.000 58.73364  ? 889  PHE   A C   1 
ATOM   1631 O O   . PHE   A 1 271 ? -63.34977 -23.59596 19.16038  1.000 65.97102  ? 889  PHE   A O   1 
ATOM   1632 C CB  . PHE   A 1 271 ? -63.41978 -23.56412 16.20841  1.000 53.88477  ? 889  PHE   A CB  1 
ATOM   1633 C CG  . PHE   A 1 271 ? -64.20420 -23.12903 15.00421  1.000 54.57146  ? 889  PHE   A CG  1 
ATOM   1634 C CD1 . PHE   A 1 271 ? -65.58550 -23.04256 15.06173  1.000 56.66855  ? 889  PHE   A CD1 1 
ATOM   1635 C CD2 . PHE   A 1 271 ? -63.55875 -22.75476 13.83156  1.000 53.49824  ? 889  PHE   A CD2 1 
ATOM   1636 C CE1 . PHE   A 1 271 ? -66.31637 -22.61921 13.96951  1.000 57.02612  ? 889  PHE   A CE1 1 
ATOM   1637 C CE2 . PHE   A 1 271 ? -64.28349 -22.32991 12.73499  1.000 54.29527  ? 889  PHE   A CE2 1 
ATOM   1638 C CZ  . PHE   A 1 271 ? -65.66617 -22.26480 12.80431  1.000 56.06178  ? 889  PHE   A CZ  1 
ATOM   1639 N N   . SER   A 1 272 ? -61.37948 -22.53732 18.91152  1.000 53.42881  ? 890  SER   A N   1 
ATOM   1640 C CA  . SER   A 1 272 ? -61.00830 -22.57958 20.31853  1.000 56.09375  ? 890  SER   A CA  1 
ATOM   1641 C C   . SER   A 1 272 ? -61.14991 -21.21908 20.98085  1.000 55.50581  ? 890  SER   A C   1 
ATOM   1642 O O   . SER   A 1 272 ? -60.79153 -21.07422 22.15408  1.000 55.57673  ? 890  SER   A O   1 
ATOM   1643 C CB  . SER   A 1 272 ? -59.57231 -23.08891 20.48425  1.000 58.69603  ? 890  SER   A CB  1 
ATOM   1644 O OG  . SER   A 1 272 ? -58.63617 -22.18624 19.92405  1.000 59.03232  ? 890  SER   A OG  1 
ATOM   1645 N N   . LEU   A 1 273 ? -61.65752 -20.22461 20.24641  1.000 54.68182  ? 891  LEU   A N   1 
ATOM   1646 C CA  . LEU   A 1 273 ? -61.84982 -18.86324 20.74730  1.000 53.44113  ? 891  LEU   A CA  1 
ATOM   1647 C C   . LEU   A 1 273 ? -60.52264 -18.24228 21.18117  1.000 52.61896  ? 891  LEU   A C   1 
ATOM   1648 O O   . LEU   A 1 273 ? -60.40540 -17.63541 22.24591  1.000 50.87114  ? 891  LEU   A O   1 
ATOM   1649 C CB  . LEU   A 1 273 ? -62.88277 -18.83178 21.87544  1.000 55.06903  ? 891  LEU   A CB  1 
ATOM   1650 C CG  . LEU   A 1 273 ? -64.27431 -19.30432 21.45481  1.000 60.71545  ? 891  LEU   A CG  1 
ATOM   1651 C CD1 . LEU   A 1 273 ? -65.18179 -19.45394 22.65664  1.000 61.03551  ? 891  LEU   A CD1 1 
ATOM   1652 C CD2 . LEU   A 1 273 ? -64.87644 -18.35057 20.44062  1.000 63.04919  ? 891  LEU   A CD2 1 
ATOM   1653 N N   . GLY   A 1 274 ? -59.51510 -18.39576 20.32991  1.000 52.54435  ? 892  GLY   A N   1 
ATOM   1654 C CA  . GLY   A 1 274 ? -58.23205 -17.77802 20.57110  1.000 54.40105  ? 892  GLY   A CA  1 
ATOM   1655 C C   . GLY   A 1 274 ? -57.25273 -18.59566 21.37500  1.000 55.32575  ? 892  GLY   A C   1 
ATOM   1656 O O   . GLY   A 1 274 ? -56.41372 -18.01863 22.07692  1.000 57.30522  ? 892  GLY   A O   1 
ATOM   1657 N N   . GLY   A 1 275 ? -57.32682 -19.92188 21.30282  1.000 53.11764  ? 893  GLY   A N   1 
ATOM   1658 C CA  . GLY   A 1 275 ? -56.36035 -20.74396 21.99726  1.000 56.49386  ? 893  GLY   A CA  1 
ATOM   1659 C C   . GLY   A 1 275 ? -55.01530 -20.76365 21.29562  1.000 56.13882  ? 893  GLY   A C   1 
ATOM   1660 O O   . GLY   A 1 275 ? -54.90301 -20.53119 20.09149  1.000 52.65058  ? 893  GLY   A O   1 
ATOM   1661 N N   . THR   A 1 276 ? -53.97421 -21.03466 22.07244  1.000 57.40306  ? 894  THR   A N   1 
ATOM   1662 C CA  . THR   A 1 276 ? -52.66130 -21.22742 21.47798  1.000 54.14480  ? 894  THR   A CA  1 
ATOM   1663 C C   . THR   A 1 276 ? -52.58122 -22.62759 20.88312  1.000 54.34324  ? 894  THR   A C   1 
ATOM   1664 O O   . THR   A 1 276 ? -52.88639 -23.60480 21.57680  1.000 58.37065  ? 894  THR   A O   1 
ATOM   1665 C CB  . THR   A 1 276 ? -51.55891 -21.03253 22.51492  1.000 60.20643  ? 894  THR   A CB  1 
ATOM   1666 O OG1 . THR   A 1 276 ? -51.61851 -19.69992 23.04001  1.000 60.50920  ? 894  THR   A OG1 1 
ATOM   1667 C CG2 . THR   A 1 276 ? -50.19547 -21.26290 21.88590  1.000 61.85679  ? 894  THR   A CG2 1 
ATOM   1668 N N   . PRO   A 1 277 ? -52.21711 -22.76060 19.60733  1.000 53.90305  ? 895  PRO   A N   1 
ATOM   1669 C CA  . PRO   A 1 277 ? -52.09378 -24.09383 19.01047  1.000 53.01102  ? 895  PRO   A CA  1 
ATOM   1670 C C   . PRO   A 1 277 ? -51.12529 -24.96769 19.79131  1.000 57.41917  ? 895  PRO   A C   1 
ATOM   1671 O O   . PRO   A 1 277 ? -50.20179 -24.47673 20.44340  1.000 57.12464  ? 895  PRO   A O   1 
ATOM   1672 C CB  . PRO   A 1 277 ? -51.56877 -23.80172 17.60202  1.000 50.25214  ? 895  PRO   A CB  1 
ATOM   1673 C CG  . PRO   A 1 277 ? -52.04640 -22.42239 17.30232  1.000 47.04316  ? 895  PRO   A CG  1 
ATOM   1674 C CD  . PRO   A 1 277 ? -52.03238 -21.68611 18.61296  1.000 49.91991  ? 895  PRO   A CD  1 
ATOM   1675 N N   . TYR   A 1 278 ? -51.34201 -26.27808 19.69720  1.000 57.88584  ? 896  TYR   A N   1 
ATOM   1676 C CA  . TYR   A 1 278 ? -50.58283 -27.29835 20.41273  1.000 57.12887  ? 896  TYR   A CA  1 
ATOM   1677 C C   . TYR   A 1 278 ? -50.34744 -26.86468 21.87136  1.000 61.98632  ? 896  TYR   A C   1 
ATOM   1678 O O   . TYR   A 1 278 ? -49.19488 -26.78650 22.30951  1.000 63.46588  ? 896  TYR   A O   1 
ATOM   1679 C CB  . TYR   A 1 278 ? -49.26639 -27.59573 19.70688  1.000 56.34799  ? 896  TYR   A CB  1 
ATOM   1680 C CG  . TYR   A 1 278 ? -49.44322 -27.88111 18.23163  1.000 52.16814  ? 896  TYR   A CG  1 
ATOM   1681 C CD1 . TYR   A 1 278 ? -49.74779 -29.15888 17.78846  1.000 50.83050  ? 896  TYR   A CD1 1 
ATOM   1682 C CD2 . TYR   A 1 278 ? -49.32253 -26.86989 17.28750  1.000 52.69112  ? 896  TYR   A CD2 1 
ATOM   1683 C CE1 . TYR   A 1 278 ? -49.91490 -29.43025 16.44866  1.000 51.20920  ? 896  TYR   A CE1 1 
ATOM   1684 C CE2 . TYR   A 1 278 ? -49.48687 -27.12658 15.94348  1.000 50.63653  ? 896  TYR   A CE2 1 
ATOM   1685 C CZ  . TYR   A 1 278 ? -49.78380 -28.40846 15.52503  1.000 52.49838  ? 896  TYR   A CZ  1 
ATOM   1686 O OH  . TYR   A 1 278 ? -49.95178 -28.66791 14.18001  1.000 53.95599  ? 896  TYR   A OH  1 
ATOM   1687 N N   . PRO   A 1 279 ? -51.41119 -26.58079 22.61909  1.000 65.32610  ? 897  PRO   A N   1 
ATOM   1688 C CA  . PRO   A 1 279 ? -51.23110 -25.95639 23.93879  1.000 71.05013  ? 897  PRO   A CA  1 
ATOM   1689 C C   . PRO   A 1 279 ? -50.40086 -26.82864 24.86658  1.000 76.58534  ? 897  PRO   A C   1 
ATOM   1690 O O   . PRO   A 1 279 ? -50.53374 -28.05438 24.88601  1.000 78.39316  ? 897  PRO   A O   1 
ATOM   1691 C CB  . PRO   A 1 279 ? -52.66571 -25.79452 24.45420  1.000 67.39869  ? 897  PRO   A CB  1 
ATOM   1692 C CG  . PRO   A 1 279 ? -53.46049 -26.79969 23.70401  1.000 60.81703  ? 897  PRO   A CG  1 
ATOM   1693 C CD  . PRO   A 1 279 ? -52.81943 -26.91693 22.35578  1.000 59.36618  ? 897  PRO   A CD  1 
ATOM   1694 N N   . GLY   A 1 280 ? -49.53251 -26.17543 25.64109  1.000 81.35058  ? 898  GLY   A N   1 
ATOM   1695 C CA  . GLY   A 1 280 ? -48.62109 -26.85709 26.53255  1.000 86.20373  ? 898  GLY   A CA  1 
ATOM   1696 C C   . GLY   A 1 280 ? -47.35966 -27.37818 25.88345  1.000 85.57865  ? 898  GLY   A C   1 
ATOM   1697 O O   . GLY   A 1 280 ? -46.36838 -27.60964 26.58730  1.000 89.95713  ? 898  GLY   A O   1 
ATOM   1698 N N   . MET   A 1 281 ? -47.35729 -27.56166 24.56579  1.000 79.26073  ? 899  MET   A N   1 
ATOM   1699 C CA  . MET   A 1 281 ? -46.22605 -28.14776 23.86124  1.000 80.18037  ? 899  MET   A CA  1 
ATOM   1700 C C   . MET   A 1 281 ? -45.22117 -27.06376 23.49592  1.000 80.30180  ? 899  MET   A C   1 
ATOM   1701 O O   . MET   A 1 281 ? -45.54724 -26.12861 22.75682  1.000 75.85764  ? 899  MET   A O   1 
ATOM   1702 C CB  . MET   A 1 281 ? -46.69549 -28.88282 22.60656  1.000 75.07298  ? 899  MET   A CB  1 
ATOM   1703 C CG  . MET   A 1 281 ? -47.32114 -30.23608 22.88206  1.000 78.42467  ? 899  MET   A CG  1 
ATOM   1704 S SD  . MET   A 1 281 ? -48.04487 -30.97747 21.40756  1.000 78.41776  ? 899  MET   A SD  1 
ATOM   1705 C CE  . MET   A 1 281 ? -46.60670 -31.09151 20.34888  1.000 73.35456  ? 899  MET   A CE  1 
ATOM   1706 N N   . MET   A 1 282 ? -44.00722 -27.19082 24.02000  1.000 82.91517  ? 900  MET   A N   1 
ATOM   1707 C CA  . MET   A 1 282 ? -42.89643 -26.38617 23.54402  1.000 85.83400  ? 900  MET   A CA  1 
ATOM   1708 C C   . MET   A 1 282 ? -42.50067 -26.83090 22.14229  1.000 82.05248  ? 900  MET   A C   1 
ATOM   1709 O O   . MET   A 1 282 ? -42.60737 -28.00860 21.78867  1.000 83.92243  ? 900  MET   A O   1 
ATOM   1710 C CB  . MET   A 1 282 ? -41.69743 -26.52512 24.48040  1.000 97.25930  ? 900  MET   A CB  1 
ATOM   1711 C CG  . MET   A 1 282 ? -42.02964 -26.44654 25.95754  1.000 109.07976 ? 900  MET   A CG  1 
ATOM   1712 S SD  . MET   A 1 282 ? -42.22840 -24.74917 26.52102  1.000 115.87057 ? 900  MET   A SD  1 
ATOM   1713 C CE  . MET   A 1 282 ? -40.74220 -24.01602 25.83986  1.000 116.82047 ? 900  MET   A CE  1 
ATOM   1714 N N   . VAL   A 1 283 ? -42.04389 -25.87721 21.33571  1.000 76.67456  ? 901  VAL   A N   1 
ATOM   1715 C CA  . VAL   A 1 283 ? -41.45425 -26.21155 20.04407  1.000 74.41081  ? 901  VAL   A CA  1 
ATOM   1716 C C   . VAL   A 1 283 ? -40.03243 -26.69679 20.30528  1.000 74.12007  ? 901  VAL   A C   1 
ATOM   1717 O O   . VAL   A 1 283 ? -39.13354 -25.90349 20.59279  1.000 77.16155  ? 901  VAL   A O   1 
ATOM   1718 C CB  . VAL   A 1 283 ? -41.47338 -25.02688 19.07285  1.000 68.91733  ? 901  VAL   A CB  1 
ATOM   1719 C CG1 . VAL   A 1 283 ? -40.70867 -25.38672 17.80859  1.000 65.81397  ? 901  VAL   A CG1 1 
ATOM   1720 C CG2 . VAL   A 1 283 ? -42.90500 -24.65219 18.73236  1.000 64.55898  ? 901  VAL   A CG2 1 
ATOM   1721 N N   . ASP   A 1 284 ? -39.83551 -28.00833 20.22934  1.000 69.10339  ? 902  ASP   A N   1 
ATOM   1722 C CA  . ASP   A 1 284 ? -38.52490 -28.61892 20.38341  1.000 75.42004  ? 902  ASP   A CA  1 
ATOM   1723 C C   . ASP   A 1 284 ? -38.44974 -29.79141 19.41249  1.000 76.39405  ? 902  ASP   A C   1 
ATOM   1724 O O   . ASP   A 1 284 ? -39.33781 -29.98529 18.57600  1.000 74.80005  ? 902  ASP   A O   1 
ATOM   1725 C CB  . ASP   A 1 284 ? -38.28161 -29.02776 21.84461  1.000 81.07613  ? 902  ASP   A CB  1 
ATOM   1726 C CG  . ASP   A 1 284 ? -39.39544 -29.90249 22.41177  1.000 81.48473  ? 902  ASP   A CG  1 
ATOM   1727 O OD1 . ASP   A 1 284 ? -40.14607 -30.51916 21.62917  1.000 79.19499  ? 902  ASP   A OD1 1 
ATOM   1728 O OD2 . ASP   A 1 284 ? -39.52349 -29.96505 23.65299  1.000 85.72393  ? 902  ASP   A OD2 1 
ATOM   1729 N N   . SER   A 1 285 ? -37.38119 -30.58327 19.52451  1.000 79.40083  ? 903  SER   A N   1 
ATOM   1730 C CA  . SER   A 1 285 ? -37.24034 -31.75231 18.66208  1.000 76.24641  ? 903  SER   A CA  1 
ATOM   1731 C C   . SER   A 1 285 ? -38.38032 -32.74228 18.86903  1.000 75.60626  ? 903  SER   A C   1 
ATOM   1732 O O   . SER   A 1 285 ? -38.79083 -33.42079 17.92055  1.000 75.95307  ? 903  SER   A O   1 
ATOM   1733 C CB  . SER   A 1 285 ? -35.89064 -32.42801 18.90698  1.000 75.92491  ? 903  SER   A CB  1 
ATOM   1734 O OG  . SER   A 1 285 ? -35.74645 -32.80182 20.26438  1.000 82.72552  ? 903  SER   A OG  1 
ATOM   1735 N N   . THR   A 1 286 ? -38.90887 -32.83275 20.09291  1.000 76.27537  ? 904  THR   A N   1 
ATOM   1736 C CA  . THR   A 1 286 ? -40.07648 -33.67513 20.33454  1.000 77.49301  ? 904  THR   A CA  1 
ATOM   1737 C C   . THR   A 1 286 ? -41.28359 -33.17832 19.54592  1.000 75.54536  ? 904  THR   A C   1 
ATOM   1738 O O   . THR   A 1 286 ? -42.03218 -33.97788 18.97108  1.000 77.56620  ? 904  THR   A O   1 
ATOM   1739 C CB  . THR   A 1 286 ? -40.39235 -33.72151 21.83186  1.000 82.97342  ? 904  THR   A CB  1 
ATOM   1740 O OG1 . THR   A 1 286 ? -39.27936 -34.27720 22.54598  1.000 87.91116  ? 904  THR   A OG1 1 
ATOM   1741 C CG2 . THR   A 1 286 ? -41.63333 -34.56808 22.09693  1.000 85.18175  ? 904  THR   A CG2 1 
ATOM   1742 N N   . PHE   A 1 287 ? -41.48349 -31.85929 19.49700  1.000 69.78235  ? 905  PHE   A N   1 
ATOM   1743 C CA  . PHE   A 1 287 ? -42.57626 -31.30844 18.70131  1.000 65.95963  ? 905  PHE   A CA  1 
ATOM   1744 C C   . PHE   A 1 287 ? -42.36399 -31.57343 17.21680  1.000 64.92673  ? 905  PHE   A C   1 
ATOM   1745 O O   . PHE   A 1 287 ? -43.29041 -31.98964 16.51140  1.000 62.19948  ? 905  PHE   A O   1 
ATOM   1746 C CB  . PHE   A 1 287 ? -42.71804 -29.80566 18.95074  1.000 64.35397  ? 905  PHE   A CB  1 
ATOM   1747 C CG  . PHE   A 1 287 ? -43.60938 -29.11500 17.95481  1.000 61.76242  ? 905  PHE   A CG  1 
ATOM   1748 C CD1 . PHE   A 1 287 ? -44.98067 -29.07366 18.14480  1.000 61.96186  ? 905  PHE   A CD1 1 
ATOM   1749 C CD2 . PHE   A 1 287 ? -43.07828 -28.52438 16.81830  1.000 61.74928  ? 905  PHE   A CD2 1 
ATOM   1750 C CE1 . PHE   A 1 287 ? -45.80784 -28.45106 17.22764  1.000 61.17932  ? 905  PHE   A CE1 1 
ATOM   1751 C CE2 . PHE   A 1 287 ? -43.90069 -27.90040 15.89410  1.000 63.96084  ? 905  PHE   A CE2 1 
ATOM   1752 C CZ  . PHE   A 1 287 ? -45.26624 -27.86185 16.10216  1.000 61.87654  ? 905  PHE   A CZ  1 
ATOM   1753 N N   . TYR   A 1 288 ? -41.15399 -31.30634 16.71945  1.000 68.59308  ? 906  TYR   A N   1 
ATOM   1754 C CA  . TYR   A 1 288 ? -40.87648 -31.48970 15.29820  1.000 66.41826  ? 906  TYR   A CA  1 
ATOM   1755 C C   . TYR   A 1 288 ? -41.11931 -32.93135 14.86590  1.000 68.01127  ? 906  TYR   A C   1 
ATOM   1756 O O   . TYR   A 1 288 ? -41.66778 -33.17856 13.78595  1.000 65.91173  ? 906  TYR   A O   1 
ATOM   1757 C CB  . TYR   A 1 288 ? -39.43668 -31.08024 14.98693  1.000 64.75836  ? 906  TYR   A CB  1 
ATOM   1758 C CG  . TYR   A 1 288 ? -39.16679 -29.59044 15.03203  1.000 65.84281  ? 906  TYR   A CG  1 
ATOM   1759 C CD1 . TYR   A 1 288 ? -40.01941 -28.68296 14.41415  1.000 62.71703  ? 906  TYR   A CD1 1 
ATOM   1760 C CD2 . TYR   A 1 288 ? -38.04883 -29.09512 15.69044  1.000 68.95267  ? 906  TYR   A CD2 1 
ATOM   1761 C CE1 . TYR   A 1 288 ? -39.76098 -27.32701 14.45067  1.000 66.05221  ? 906  TYR   A CE1 1 
ATOM   1762 C CE2 . TYR   A 1 288 ? -37.78471 -27.74382 15.73071  1.000 68.24596  ? 906  TYR   A CE2 1 
ATOM   1763 C CZ  . TYR   A 1 288 ? -38.64095 -26.86124 15.11193  1.000 68.69097  ? 906  TYR   A CZ  1 
ATOM   1764 O OH  . TYR   A 1 288 ? -38.36705 -25.51693 15.16301  1.000 73.11918  ? 906  TYR   A OH  1 
ATOM   1765 N N   . ASN   A 1 289 ? -40.72543 -33.89840 15.69873  1.000 65.57433  ? 907  ASN   A N   1 
ATOM   1766 C CA  . ASN   A 1 289 ? -40.87369 -35.30051 15.31861  1.000 68.09517  ? 907  ASN   A CA  1 
ATOM   1767 C C   . ASN   A 1 289 ? -42.33454 -35.73474 15.32337  1.000 64.47794  ? 907  ASN   A C   1 
ATOM   1768 O O   . ASN   A 1 289 ? -42.74148 -36.56915 14.50545  1.000 63.81741  ? 907  ASN   A O   1 
ATOM   1769 C CB  . ASN   A 1 289 ? -40.04731 -36.18270 16.24724  1.000 70.37421  ? 907  ASN   A CB  1 
ATOM   1770 C CG  . ASN   A 1 289 ? -38.58763 -36.19950 15.86763  1.000 74.48188  ? 907  ASN   A CG  1 
ATOM   1771 O OD1 . ASN   A 1 289 ? -38.22317 -35.78148 14.76376  1.000 77.02010  ? 907  ASN   A OD1 1 
ATOM   1772 N ND2 . ASN   A 1 289 ? -37.74255 -36.69139 16.76651  1.000 71.18126  ? 907  ASN   A ND2 1 
ATOM   1773 N N   . LYS   A 1 290 ? -43.13437 -35.19212 16.24308  1.000 64.10160  ? 908  LYS   A N   1 
ATOM   1774 C CA  . LYS   A 1 290 ? -44.55826 -35.51427 16.27363  1.000 67.85466  ? 908  LYS   A CA  1 
ATOM   1775 C C   . LYS   A 1 290 ? -45.24951 -35.06636 14.99088  1.000 64.93710  ? 908  LYS   A C   1 
ATOM   1776 O O   . LYS   A 1 290 ? -46.05536 -35.80573 14.41183  1.000 64.37330  ? 908  LYS   A O   1 
ATOM   1777 C CB  . LYS   A 1 290 ? -45.21177 -34.85728 17.48882  1.000 71.13932  ? 908  LYS   A CB  1 
ATOM   1778 C CG  . LYS   A 1 290 ? -45.04389 -35.61563 18.78885  1.000 78.10949  ? 908  LYS   A CG  1 
ATOM   1779 C CD  . LYS   A 1 290 ? -45.36814 -34.74760 19.98818  1.000 84.08963  ? 908  LYS   A CD  1 
ATOM   1780 C CE  . LYS   A 1 290 ? -45.58531 -35.58355 21.24101  1.000 92.25354  ? 908  LYS   A CE  1 
ATOM   1781 N NZ  . LYS   A 1 290 ? -46.83142 -36.40095 21.17065  1.000 96.97279  ? 908  LYS   A NZ  1 
ATOM   1782 N N   . ILE   A 1 291 ? -44.94209 -33.84822 14.53493  1.000 65.09875  ? 909  ILE   A N   1 
ATOM   1783 C CA  . ILE   A 1 291 ? -45.54030 -33.32171 13.30842  1.000 62.89351  ? 909  ILE   A CA  1 
ATOM   1784 C C   . ILE   A 1 291 ? -45.19199 -34.21187 12.12031  1.000 66.48852  ? 909  ILE   A C   1 
ATOM   1785 O O   . ILE   A 1 291 ? -46.06642 -34.60057 11.33678  1.000 67.19802  ? 909  ILE   A O   1 
ATOM   1786 C CB  . ILE   A 1 291 ? -45.09007 -31.86855 13.06675  1.000 62.37297  ? 909  ILE   A CB  1 
ATOM   1787 C CG1 . ILE   A 1 291 ? -45.54117 -30.94474 14.20695  1.000 68.15916  ? 909  ILE   A CG1 1 
ATOM   1788 C CG2 . ILE   A 1 291 ? -45.61711 -31.36736 11.73446  1.000 60.70389  ? 909  ILE   A CG2 1 
ATOM   1789 C CD1 . ILE   A 1 291 ? -47.04965 -30.72956 14.30455  1.000 67.74586  ? 909  ILE   A CD1 1 
ATOM   1790 N N   . LYS   A 1 292 ? -43.90727 -34.55099 11.96798  1.000 64.51872  ? 910  LYS   A N   1 
ATOM   1791 C CA  . LYS   A 1 292 ? -43.51456 -35.44642 10.88348  1.000 64.92486  ? 910  LYS   A CA  1 
ATOM   1792 C C   . LYS   A 1 292 ? -44.19108 -36.81001 10.99379  1.000 67.63690  ? 910  LYS   A C   1 
ATOM   1793 O O   . LYS   A 1 292 ? -44.44339 -37.45827 9.97025   1.000 69.53645  ? 910  LYS   A O   1 
ATOM   1794 C CB  . LYS   A 1 292 ? -41.99476 -35.63482 10.85826  1.000 64.84426  ? 910  LYS   A CB  1 
ATOM   1795 C CG  . LYS   A 1 292 ? -41.17685 -34.36547 10.77190  1.000 67.43466  ? 910  LYS   A CG  1 
ATOM   1796 C CD  . LYS   A 1 292 ? -39.71974 -34.67060 10.50423  1.000 70.90432  ? 910  LYS   A CD  1 
ATOM   1797 C CE  . LYS   A 1 292 ? -38.80704 -33.85466 11.40467  1.000 72.55988  ? 910  LYS   A CE  1 
ATOM   1798 N NZ  . LYS   A 1 292 ? -37.37769 -34.09896 11.11025  1.000 76.66681  ? 910  LYS   A NZ  1 
ATOM   1799 N N   . SER   A 1 293 ? -44.49266 -37.26138 12.21222  1.000 67.75059  ? 911  SER   A N   1 
ATOM   1800 C CA  . SER   A 1 293 ? -45.10562 -38.56869 12.41863  1.000 65.68516  ? 911  SER   A CA  1 
ATOM   1801 C C   . SER   A 1 293 ? -46.62280 -38.54016 12.30513  1.000 64.60773  ? 911  SER   A C   1 
ATOM   1802 O O   . SER   A 1 293 ? -47.26565 -39.55496 12.59456  1.000 70.40962  ? 911  SER   A O   1 
ATOM   1803 C CB  . SER   A 1 293 ? -44.71066 -39.13715 13.78724  1.000 71.13758  ? 911  SER   A CB  1 
ATOM   1804 O OG  . SER   A 1 293 ? -43.31097 -39.32570 13.88058  1.000 76.90646  ? 911  SER   A OG  1 
ATOM   1805 N N   . GLY   A 1 294 ? -47.20549 -37.40976 11.91943  1.000 63.87694  ? 912  GLY   A N   1 
ATOM   1806 C CA  . GLY   A 1 294 ? -48.63092 -37.31349 11.70064  1.000 66.00494  ? 912  GLY   A CA  1 
ATOM   1807 C C   . GLY   A 1 294 ? -49.44691 -36.81659 12.87116  1.000 66.77764  ? 912  GLY   A C   1 
ATOM   1808 O O   . GLY   A 1 294 ? -50.67653 -36.93331 12.83098  1.000 70.01507  ? 912  GLY   A O   1 
ATOM   1809 N N   . TYR   A 1 295 ? -48.81874 -36.27076 13.91086  1.000 62.45187  ? 913  TYR   A N   1 
ATOM   1810 C CA  . TYR   A 1 295 ? -49.59117 -35.74575 15.02759  1.000 61.49907  ? 913  TYR   A CA  1 
ATOM   1811 C C   . TYR   A 1 295 ? -50.36792 -34.51121 14.59287  1.000 59.15320  ? 913  TYR   A C   1 
ATOM   1812 O O   . TYR   A 1 295 ? -49.82510 -33.62861 13.92335  1.000 61.60985  ? 913  TYR   A O   1 
ATOM   1813 C CB  . TYR   A 1 295 ? -48.68825 -35.40102 16.21393  1.000 63.38345  ? 913  TYR   A CB  1 
ATOM   1814 C CG  . TYR   A 1 295 ? -49.46612 -34.81925 17.37519  1.000 67.09878  ? 913  TYR   A CG  1 
ATOM   1815 C CD1 . TYR   A 1 295 ? -49.99745 -35.64091 18.35918  1.000 67.90775  ? 913  TYR   A CD1 1 
ATOM   1816 C CD2 . TYR   A 1 295 ? -49.68647 -33.44939 17.47474  1.000 63.32582  ? 913  TYR   A CD2 1 
ATOM   1817 C CE1 . TYR   A 1 295 ? -50.72002 -35.11648 19.41352  1.000 69.82420  ? 913  TYR   A CE1 1 
ATOM   1818 C CE2 . TYR   A 1 295 ? -50.40673 -32.91588 18.52221  1.000 63.50695  ? 913  TYR   A CE2 1 
ATOM   1819 C CZ  . TYR   A 1 295 ? -50.92209 -33.75283 19.48993  1.000 70.46864  ? 913  TYR   A CZ  1 
ATOM   1820 O OH  . TYR   A 1 295 ? -51.63516 -33.22424 20.53879  1.000 74.01811  ? 913  TYR   A OH  1 
ATOM   1821 N N   . ARG   A 1 296 ? -51.63969 -34.44746 14.98403  1.000 58.24130  ? 914  ARG   A N   1 
ATOM   1822 C CA  . ARG   A 1 296 ? -52.48174 -33.29046 14.71698  1.000 59.24246  ? 914  ARG   A CA  1 
ATOM   1823 C C   . ARG   A 1 296 ? -53.29533 -32.96235 15.95912  1.000 59.74780  ? 914  ARG   A C   1 
ATOM   1824 O O   . ARG   A 1 296 ? -53.59679 -33.83890 16.77427  1.000 61.44972  ? 914  ARG   A O   1 
ATOM   1825 C CB  . ARG   A 1 296 ? -53.42971 -33.53120 13.53632  1.000 53.99528  ? 914  ARG   A CB  1 
ATOM   1826 C CG  . ARG   A 1 296 ? -52.75060 -33.98444 12.25736  1.000 54.09683  ? 914  ARG   A CG  1 
ATOM   1827 C CD  . ARG   A 1 296 ? -51.89937 -32.87695 11.64778  1.000 53.02479  ? 914  ARG   A CD  1 
ATOM   1828 N NE  . ARG   A 1 296 ? -51.35299 -33.28859 10.35866  1.000 57.69911  ? 914  ARG   A NE  1 
ATOM   1829 C CZ  . ARG   A 1 296 ? -50.10232 -33.69400 10.17195  1.000 60.41352  ? 914  ARG   A CZ  1 
ATOM   1830 N NH1 . ARG   A 1 296 ? -49.25285 -33.73080 11.18957  1.000 53.00669  ? 914  ARG   A NH1 1 
ATOM   1831 N NH2 . ARG   A 1 296 ? -49.70034 -34.06499 8.96630   1.000 63.36407  ? 914  ARG   A NH2 1 
ATOM   1832 N N   . MET   A 1 297 ? -53.65656 -31.68735 16.08258  1.000 58.12461  ? 915  MET   A N   1 
ATOM   1833 C CA  . MET   A 1 297 ? -54.43395 -31.22177 17.22229  1.000 59.88150  ? 915  MET   A CA  1 
ATOM   1834 C C   . MET   A 1 297 ? -55.80727 -31.88469 17.25795  1.000 57.65394  ? 915  MET   A C   1 
ATOM   1835 O O   . MET   A 1 297 ? -56.39143 -32.21948 16.22319  1.000 57.24204  ? 915  MET   A O   1 
ATOM   1836 C CB  . MET   A 1 297 ? -54.59626 -29.70126 17.16627  1.000 63.54786  ? 915  MET   A CB  1 
ATOM   1837 C CG  . MET   A 1 297 ? -53.35823 -28.90571 17.52949  1.000 62.75624  ? 915  MET   A CG  1 
ATOM   1838 S SD  . MET   A 1 297 ? -53.71697 -27.14833 17.70448  1.000 57.08359  ? 915  MET   A SD  1 
ATOM   1839 C CE  . MET   A 1 297 ? -53.66051 -26.59903 16.00257  1.000 47.85730  ? 915  MET   A CE  1 
ATOM   1840 N N   . ALA   A 1 298 ? -56.32195 -32.07179 18.47110  1.000 56.44479  ? 916  ALA   A N   1 
ATOM   1841 C CA  . ALA   A 1 298 ? -57.68327 -32.54854 18.63765  1.000 58.20460  ? 916  ALA   A CA  1 
ATOM   1842 C C   . ALA   A 1 298 ? -58.67722 -31.42559 18.33283  1.000 59.08203  ? 916  ALA   A C   1 
ATOM   1843 O O   . ALA   A 1 298 ? -58.31183 -30.26756 18.13202  1.000 56.64786  ? 916  ALA   A O   1 
ATOM   1844 C CB  . ALA   A 1 298 ? -57.89501 -33.09162 20.04989  1.000 60.96350  ? 916  ALA   A CB  1 
ATOM   1845 N N   . LYS   A 1 299 ? -59.94923 -31.78433 18.30467  1.000 65.45048  ? 917  LYS   A N   1 
ATOM   1846 C CA  . LYS   A 1 299 ? -60.99213 -30.84036 17.92116  1.000 63.27186  ? 917  LYS   A CA  1 
ATOM   1847 C C   . LYS   A 1 299 ? -61.17377 -29.77380 18.99394  1.000 58.99466  ? 917  LYS   A C   1 
ATOM   1848 O O   . LYS   A 1 299 ? -61.33148 -30.11040 20.17396  1.000 60.63004  ? 917  LYS   A O   1 
ATOM   1849 C CB  . LYS   A 1 299 ? -62.31026 -31.58112 17.68461  1.000 67.65545  ? 917  LYS   A CB  1 
ATOM   1850 C CG  . LYS   A 1 299 ? -63.48335 -30.67974 17.34865  1.000 71.11471  ? 917  LYS   A CG  1 
ATOM   1851 C CD  . LYS   A 1 299 ? -64.76954 -31.48389 17.21760  1.000 77.58437  ? 917  LYS   A CD  1 
ATOM   1852 C CE  . LYS   A 1 299 ? -65.25326 -31.98281 18.57545  1.000 85.40804  ? 917  LYS   A CE  1 
ATOM   1853 N NZ  . LYS   A 1 299 ? -65.63451 -30.86279 19.48528  1.000 87.19716  ? 917  LYS   A NZ  1 
ATOM   1854 N N   . PRO   A 1 300 ? -61.17615 -28.49053 18.62843  1.000 58.24120  ? 918  PRO   A N   1 
ATOM   1855 C CA  . PRO   A 1 300 ? -61.47175 -27.44522 19.61333  1.000 58.28272  ? 918  PRO   A CA  1 
ATOM   1856 C C   . PRO   A 1 300 ? -62.89069 -27.58683 20.14134  1.000 60.86485  ? 918  PRO   A C   1 
ATOM   1857 O O   . PRO   A 1 300 ? -63.75457 -28.20816 19.51877  1.000 59.53631  ? 918  PRO   A O   1 
ATOM   1858 C CB  . PRO   A 1 300 ? -61.30091 -26.13952 18.82463  1.000 56.39853  ? 918  PRO   A CB  1 
ATOM   1859 C CG  . PRO   A 1 300 ? -60.58797 -26.50651 17.58084  1.000 55.66904  ? 918  PRO   A CG  1 
ATOM   1860 C CD  . PRO   A 1 300 ? -60.89966 -27.93535 17.29142  1.000 58.57549  ? 918  PRO   A CD  1 
ATOM   1861 N N   . ASP   A 1 301 ? -63.12117 -26.99141 21.31490  1.000 71.58527  ? 919  ASP   A N   1 
ATOM   1862 C CA  . ASP   A 1 301 ? -64.40267 -27.14610 21.99987  1.000 80.37822  ? 919  ASP   A CA  1 
ATOM   1863 C C   . ASP   A 1 301 ? -65.57625 -26.73750 21.11927  1.000 77.30599  ? 919  ASP   A C   1 
ATOM   1864 O O   . ASP   A 1 301 ? -66.59177 -27.44054 21.05994  1.000 80.14224  ? 919  ASP   A O   1 
ATOM   1865 C CB  . ASP   A 1 301 ? -64.40830 -26.32421 23.28948  1.000 91.78044  ? 919  ASP   A CB  1 
ATOM   1866 C CG  . ASP   A 1 301 ? -63.57863 -26.95588 24.38913  1.000 105.96685 ? 919  ASP   A CG  1 
ATOM   1867 O OD1 . ASP   A 1 301 ? -62.98177 -28.02935 24.15366  1.000 112.85378 ? 919  ASP   A OD1 1 
ATOM   1868 O OD2 . ASP   A 1 301 ? -63.52904 -26.37725 25.49493  1.000 113.57548 ? 919  ASP   A OD2 1 
ATOM   1869 N N   . HIS   A 1 302 ? -65.45551 -25.60608 20.42475  1.000 70.51478  ? 920  HIS   A N   1 
ATOM   1870 C CA  . HIS   A 1 302 ? -66.57177 -25.01505 19.70019  1.000 67.95885  ? 920  HIS   A CA  1 
ATOM   1871 C C   . HIS   A 1 302 ? -66.54357 -25.32212 18.20980  1.000 64.86683  ? 920  HIS   A C   1 
ATOM   1872 O O   . HIS   A 1 302 ? -67.22686 -24.64643 17.43121  1.000 65.84362  ? 920  HIS   A O   1 
ATOM   1873 C CB  . HIS   A 1 302 ? -66.60343 -23.50664 19.93413  1.000 63.66710  ? 920  HIS   A CB  1 
ATOM   1874 C CG  . HIS   A 1 302 ? -66.64600 -23.13120 21.38154  1.000 70.44462  ? 920  HIS   A CG  1 
ATOM   1875 N ND1 . HIS   A 1 302 ? -67.81700 -23.09612 22.10774  1.000 75.50714  ? 920  HIS   A ND1 1 
ATOM   1876 C CD2 . HIS   A 1 302 ? -65.65731 -22.79933 22.24528  1.000 72.75901  ? 920  HIS   A CD2 1 
ATOM   1877 C CE1 . HIS   A 1 302 ? -67.54875 -22.74836 23.35403  1.000 77.52865  ? 920  HIS   A CE1 1 
ATOM   1878 N NE2 . HIS   A 1 302 ? -66.24561 -22.56162 23.46383  1.000 76.61067  ? 920  HIS   A NE2 1 
ATOM   1879 N N   . ALA   A 1 303 ? -65.77135 -26.32020 17.79683  1.000 60.21789  ? 921  ALA   A N   1 
ATOM   1880 C CA  . ALA   A 1 303 ? -65.81313 -26.79497 16.42446  1.000 59.54015  ? 921  ALA   A CA  1 
ATOM   1881 C C   . ALA   A 1 303 ? -66.87295 -27.87605 16.28530  1.000 65.38563  ? 921  ALA   A C   1 
ATOM   1882 O O   . ALA   A 1 303 ? -67.02303 -28.73407 17.15826  1.000 70.89807  ? 921  ALA   A O   1 
ATOM   1883 C CB  . ALA   A 1 303 ? -64.45176 -27.33896 15.99442  1.000 52.37815  ? 921  ALA   A CB  1 
ATOM   1884 N N   . THR   A 1 304 ? -67.62289 -27.81466 15.19314  1.000 65.59400  ? 922  THR   A N   1 
ATOM   1885 C CA  . THR   A 1 304 ? -68.45272 -28.94156 14.80259  1.000 63.99152  ? 922  THR   A CA  1 
ATOM   1886 C C   . THR   A 1 304 ? -67.58590 -29.99929 14.12524  1.000 65.68281  ? 922  THR   A C   1 
ATOM   1887 O O   . THR   A 1 304 ? -66.41569 -29.76837 13.80589  1.000 61.84988  ? 922  THR   A O   1 
ATOM   1888 C CB  . THR   A 1 304 ? -69.57276 -28.48901 13.86605  1.000 64.95556  ? 922  THR   A CB  1 
ATOM   1889 O OG1 . THR   A 1 304 ? -68.99867 -27.89146 12.69762  1.000 60.77014  ? 922  THR   A OG1 1 
ATOM   1890 C CG2 . THR   A 1 304 ? -70.46781 -27.47738 14.55149  1.000 63.07817  ? 922  THR   A CG2 1 
ATOM   1891 N N   . SER   A 1 305 ? -68.16436 -31.18297 13.92465  1.000 71.08030  ? 923  SER   A N   1 
ATOM   1892 C CA  . SER   A 1 305 ? -67.43960 -32.22610 13.20850  1.000 70.61902  ? 923  SER   A CA  1 
ATOM   1893 C C   . SER   A 1 305 ? -67.08234 -31.76531 11.80043  1.000 67.45216  ? 923  SER   A C   1 
ATOM   1894 O O   . SER   A 1 305 ? -65.95874 -31.98619 11.32995  1.000 68.27572  ? 923  SER   A O   1 
ATOM   1895 C CB  . SER   A 1 305 ? -68.26827 -33.50915 13.15873  1.000 73.75155  ? 923  SER   A CB  1 
ATOM   1896 O OG  . SER   A 1 305 ? -68.89728 -33.76433 14.40287  1.000 82.34431  ? 923  SER   A OG  1 
ATOM   1897 N N   . GLU   A 1 306 ? -68.02156 -31.09289 11.12674  1.000 64.09066  ? 924  GLU   A N   1 
ATOM   1898 C CA  . GLU   A 1 306 ? -67.76898 -30.58843 9.77982   1.000 69.04963  ? 924  GLU   A CA  1 
ATOM   1899 C C   . GLU   A 1 306 ? -66.58489 -29.63059 9.75577   1.000 64.63657  ? 924  GLU   A C   1 
ATOM   1900 O O   . GLU   A 1 306 ? -65.75338 -29.68069 8.84108   1.000 61.93247  ? 924  GLU   A O   1 
ATOM   1901 C CB  . GLU   A 1 306 ? -69.01965 -29.89705 9.23453   1.000 77.31532  ? 924  GLU   A CB  1 
ATOM   1902 C CG  . GLU   A 1 306 ? -70.19977 -30.82113 8.96501   1.000 89.97270  ? 924  GLU   A CG  1 
ATOM   1903 C CD  . GLU   A 1 306 ? -71.01675 -31.11868 10.20641  1.000 99.69843  ? 924  GLU   A CD  1 
ATOM   1904 O OE1 . GLU   A 1 306 ? -70.80806 -30.43694 11.23250  1.000 103.15151 ? 924  GLU   A OE1 1 
ATOM   1905 O OE2 . GLU   A 1 306 ? -71.86758 -32.03209 10.15587  1.000 112.60715 ? 924  GLU   A OE2 1 
ATOM   1906 N N   . VAL   A 1 307 ? -66.49480 -28.74873 10.75300  1.000 63.99032  ? 925  VAL   A N   1 
ATOM   1907 C CA  . VAL   A 1 307 ? -65.40367 -27.78010 10.79743  1.000 61.32802  ? 925  VAL   A CA  1 
ATOM   1908 C C   . VAL   A 1 307 ? -64.08714 -28.46969 11.13014  1.000 59.18724  ? 925  VAL   A C   1 
ATOM   1909 O O   . VAL   A 1 307 ? -63.02507 -28.09578 10.61458  1.000 56.33200  ? 925  VAL   A O   1 
ATOM   1910 C CB  . VAL   A 1 307 ? -65.72860 -26.65775 11.79977  1.000 58.15450  ? 925  VAL   A CB  1 
ATOM   1911 C CG1 . VAL   A 1 307 ? -64.54161 -25.71987 11.95591  1.000 59.58986  ? 925  VAL   A CG1 1 
ATOM   1912 C CG2 . VAL   A 1 307 ? -66.95414 -25.89114 11.34545  1.000 56.87896  ? 925  VAL   A CG2 1 
ATOM   1913 N N   . TYR   A 1 308 ? -64.12889 -29.49226 11.98484  1.000 58.55835  ? 926  TYR   A N   1 
ATOM   1914 C CA  . TYR   A 1 308 ? -62.90308 -30.22342 12.28546  1.000 57.42735  ? 926  TYR   A CA  1 
ATOM   1915 C C   . TYR   A 1 308 ? -62.39119 -30.95977 11.05745  1.000 60.96703  ? 926  TYR   A C   1 
ATOM   1916 O O   . TYR   A 1 308 ? -61.18770 -30.94411 10.77143  1.000 58.96098  ? 926  TYR   A O   1 
ATOM   1917 C CB  . TYR   A 1 308 ? -63.11957 -31.20151 13.43858  1.000 62.09561  ? 926  TYR   A CB  1 
ATOM   1918 C CG  . TYR   A 1 308 ? -61.82237 -31.80952 13.92122  1.000 62.39289  ? 926  TYR   A CG  1 
ATOM   1919 C CD1 . TYR   A 1 308 ? -60.75161 -31.00046 14.27719  1.000 57.89084  ? 926  TYR   A CD1 1 
ATOM   1920 C CD2 . TYR   A 1 308 ? -61.66439 -33.18686 14.01907  1.000 64.13155  ? 926  TYR   A CD2 1 
ATOM   1921 C CE1 . TYR   A 1 308 ? -59.56105 -31.54165 14.71968  1.000 59.38416  ? 926  TYR   A CE1 1 
ATOM   1922 C CE2 . TYR   A 1 308 ? -60.47675 -33.73818 14.46131  1.000 63.27138  ? 926  TYR   A CE2 1 
ATOM   1923 C CZ  . TYR   A 1 308 ? -59.42968 -32.91133 14.80873  1.000 61.64191  ? 926  TYR   A CZ  1 
ATOM   1924 O OH  . TYR   A 1 308 ? -58.24824 -33.46514 15.24829  1.000 64.75188  ? 926  TYR   A OH  1 
ATOM   1925 N N   . GLU   A 1 309 ? -63.29726 -31.60678 10.31860  1.000 62.96404  ? 927  GLU   A N   1 
ATOM   1926 C CA  . GLU   A 1 309 ? -62.91319 -32.29388 9.08981   1.000 62.60680  ? 927  GLU   A CA  1 
ATOM   1927 C C   . GLU   A 1 309 ? -62.19370 -31.35430 8.13743   1.000 59.07494  ? 927  GLU   A C   1 
ATOM   1928 O O   . GLU   A 1 309 ? -61.21620 -31.74225 7.48711   1.000 54.64577  ? 927  GLU   A O   1 
ATOM   1929 C CB  . GLU   A 1 309 ? -64.14873 -32.88983 8.40922   1.000 61.54666  ? 927  GLU   A CB  1 
ATOM   1930 N N   . ILE   A 1 310 ? -62.65883 -30.10664 8.05605   1.000 55.28598  ? 928  ILE   A N   1 
ATOM   1931 C CA  . ILE   A 1 310 ? -62.00805 -29.11719 7.20315   1.000 55.68131  ? 928  ILE   A CA  1 
ATOM   1932 C C   . ILE   A 1 310 ? -60.57137 -28.88219 7.65513   1.000 55.53036  ? 928  ILE   A C   1 
ATOM   1933 O O   . ILE   A 1 310 ? -59.64774 -28.82858 6.83311   1.000 58.67657  ? 928  ILE   A O   1 
ATOM   1934 C CB  . ILE   A 1 310 ? -62.81853 -27.80771 7.19335   1.000 52.14176  ? 928  ILE   A CB  1 
ATOM   1935 C CG1 . ILE   A 1 310 ? -64.17427 -28.01189 6.51865   1.000 53.66169  ? 928  ILE   A CG1 1 
ATOM   1936 C CG2 . ILE   A 1 310 ? -62.04478 -26.71499 6.49514   1.000 52.93808  ? 928  ILE   A CG2 1 
ATOM   1937 C CD1 . ILE   A 1 310 ? -65.10204 -26.82478 6.67821   1.000 57.63468  ? 928  ILE   A CD1 1 
ATOM   1938 N N   . MET   A 1 311 ? -60.36160 -28.73246 8.96767   1.000 54.41278  ? 929  MET   A N   1 
ATOM   1939 C CA  . MET   A 1 311 ? -59.01256 -28.52952 9.49241   1.000 53.70192  ? 929  MET   A CA  1 
ATOM   1940 C C   . MET   A 1 311 ? -58.09864 -29.69745 9.14305   1.000 57.46105  ? 929  MET   A C   1 
ATOM   1941 O O   . MET   A 1 311 ? -56.96138 -29.50052 8.69477   1.000 54.32429  ? 929  MET   A O   1 
ATOM   1942 C CB  . MET   A 1 311 ? -59.04930 -28.35421 11.00920  1.000 55.21474  ? 929  MET   A CB  1 
ATOM   1943 C CG  . MET   A 1 311 ? -60.00460 -27.30802 11.54113  1.000 57.62959  ? 929  MET   A CG  1 
ATOM   1944 S SD  . MET   A 1 311 ? -59.82742 -27.23794 13.33445  1.000 57.98246  ? 929  MET   A SD  1 
ATOM   1945 C CE  . MET   A 1 311 ? -61.23294 -26.22838 13.79001  1.000 52.75999  ? 929  MET   A CE  1 
ATOM   1946 N N   . VAL   A 1 312 ? -58.57893 -30.92334 9.35964   1.000 59.28974  ? 930  VAL   A N   1 
ATOM   1947 C CA  . VAL   A 1 312 ? -57.76419 -32.11166 9.12018   1.000 61.97878  ? 930  VAL   A CA  1 
ATOM   1948 C C   . VAL   A 1 312 ? -57.35390 -32.19310 7.65908   1.000 64.12817  ? 930  VAL   A C   1 
ATOM   1949 O O   . VAL   A 1 312 ? -56.21006 -32.54113 7.33759   1.000 71.49232  ? 930  VAL   A O   1 
ATOM   1950 C CB  . VAL   A 1 312 ? -58.52306 -33.37539 9.56434   1.000 59.91036  ? 930  VAL   A CB  1 
ATOM   1951 C CG1 . VAL   A 1 312 ? -57.78982 -34.62627 9.09883   1.000 61.24499  ? 930  VAL   A CG1 1 
ATOM   1952 C CG2 . VAL   A 1 312 ? -58.70242 -33.38177 11.07118  1.000 56.13860  ? 930  VAL   A CG2 1 
ATOM   1953 N N   . LYS   A 1 313 ? -58.27757 -31.86763 6.75276   1.000 62.43845  ? 931  LYS   A N   1 
ATOM   1954 C CA  . LYS   A 1 313 ? -57.93088 -31.80549 5.33838   1.000 60.89381  ? 931  LYS   A CA  1 
ATOM   1955 C C   . LYS   A 1 313 ? -56.80429 -30.81326 5.08865   1.000 55.27698  ? 931  LYS   A C   1 
ATOM   1956 O O   . LYS   A 1 313 ? -55.91503 -31.06810 4.26791   1.000 51.36918  ? 931  LYS   A O   1 
ATOM   1957 C CB  . LYS   A 1 313 ? -59.15634 -31.42918 4.50847   1.000 65.73630  ? 931  LYS   A CB  1 
ATOM   1958 C CG  . LYS   A 1 313 ? -60.24206 -32.47867 4.43314   1.000 71.96741  ? 931  LYS   A CG  1 
ATOM   1959 C CD  . LYS   A 1 313 ? -61.36551 -31.99259 3.52957   1.000 74.93912  ? 931  LYS   A CD  1 
ATOM   1960 C CE  . LYS   A 1 313 ? -62.39534 -33.07866 3.27257   1.000 81.02124  ? 931  LYS   A CE  1 
ATOM   1961 N NZ  . LYS   A 1 313 ? -63.45141 -32.62984 2.32113   1.000 87.96975  ? 931  LYS   A NZ  1 
ATOM   1962 N N   . CYS   A 1 314 ? -56.82679 -29.67421 5.78487   1.000 53.45953  ? 932  CYS   A N   1 
ATOM   1963 C CA  . CYS   A 1 314 ? -55.78232 -28.67392 5.59419   1.000 53.93755  ? 932  CYS   A CA  1 
ATOM   1964 C C   . CYS   A 1 314 ? -54.43277 -29.16526 6.09775   1.000 56.82396  ? 932  CYS   A C   1 
ATOM   1965 O O   . CYS   A 1 314 ? -53.38977 -28.66550 5.66255   1.000 59.26975  ? 932  CYS   A O   1 
ATOM   1966 C CB  . CYS   A 1 314 ? -56.15870 -27.36866 6.30062   1.000 52.02845  ? 932  CYS   A CB  1 
ATOM   1967 S SG  . CYS   A 1 314 ? -57.57281 -26.49642 5.59093   1.000 54.12319  ? 932  CYS   A SG  1 
ATOM   1968 N N   . TRP   A 1 315 ? -54.42850 -30.13244 7.01484   1.000 54.37810  ? 933  TRP   A N   1 
ATOM   1969 C CA  . TRP   A 1 315 ? -53.20393 -30.63017 7.62798   1.000 56.01841  ? 933  TRP   A CA  1 
ATOM   1970 C C   . TRP   A 1 315 ? -52.70915 -31.92295 6.98946   1.000 56.95166  ? 933  TRP   A C   1 
ATOM   1971 O O   . TRP   A 1 315 ? -52.04022 -32.71989 7.65356   1.000 56.59824  ? 933  TRP   A O   1 
ATOM   1972 C CB  . TRP   A 1 315 ? -53.40671 -30.84181 9.12571   1.000 56.82342  ? 933  TRP   A CB  1 
ATOM   1973 C CG  . TRP   A 1 315 ? -53.78048 -29.61603 9.87370   1.000 52.96378  ? 933  TRP   A CG  1 
ATOM   1974 C CD1 . TRP   A 1 315 ? -53.47908 -28.32661 9.55320   1.000 54.33225  ? 933  TRP   A CD1 1 
ATOM   1975 C CD2 . TRP   A 1 315 ? -54.54694 -29.56448 11.07910  1.000 54.15480  ? 933  TRP   A CD2 1 
ATOM   1976 N NE1 . TRP   A 1 315 ? -54.00817 -27.47221 10.49430  1.000 55.02048  ? 933  TRP   A NE1 1 
ATOM   1977 C CE2 . TRP   A 1 315 ? -54.67061 -28.20936 11.43994  1.000 54.17900  ? 933  TRP   A CE2 1 
ATOM   1978 C CE3 . TRP   A 1 315 ? -55.13628 -30.53614 11.89162  1.000 53.91239  ? 933  TRP   A CE3 1 
ATOM   1979 C CZ2 . TRP   A 1 315 ? -55.35955 -27.80125 12.57564  1.000 53.95717  ? 933  TRP   A CZ2 1 
ATOM   1980 C CZ3 . TRP   A 1 315 ? -55.82394 -30.12823 13.01929  1.000 56.93716  ? 933  TRP   A CZ3 1 
ATOM   1981 C CH2 . TRP   A 1 315 ? -55.92848 -28.77468 13.35106  1.000 56.56101  ? 933  TRP   A CH2 1 
ATOM   1982 N N   . ASN   A 1 316 ? -53.04352 -32.16731 5.72597   1.000 56.64900  ? 934  ASN   A N   1 
ATOM   1983 C CA  . ASN   A 1 316 ? -52.51584 -33.34508 5.05317   1.000 60.98543  ? 934  ASN   A CA  1 
ATOM   1984 C C   . ASN   A 1 316 ? -51.00961 -33.19465 4.88602   1.000 63.18145  ? 934  ASN   A C   1 
ATOM   1985 O O   . ASN   A 1 316 ? -50.52175 -32.13991 4.46939   1.000 60.88260  ? 934  ASN   A O   1 
ATOM   1986 C CB  . ASN   A 1 316 ? -53.19201 -33.54383 3.69518   1.000 59.52055  ? 934  ASN   A CB  1 
ATOM   1987 C CG  . ASN   A 1 316 ? -53.00245 -34.95506 3.14657   1.000 68.46158  ? 934  ASN   A CG  1 
ATOM   1988 O OD1 . ASN   A 1 316 ? -51.89326 -35.35296 2.78893   1.000 73.32051  ? 934  ASN   A OD1 1 
ATOM   1989 N ND2 . ASN   A 1 316 ? -54.09191 -35.71275 3.07292   1.000 70.80765  ? 934  ASN   A ND2 1 
ATOM   1990 N N   . SER   A 1 317 ? -50.26904 -34.25137 5.23284   1.000 67.89900  ? 935  SER   A N   1 
ATOM   1991 C CA  . SER   A 1 317 ? -48.81400 -34.19825 5.12720   1.000 68.14865  ? 935  SER   A CA  1 
ATOM   1992 C C   . SER   A 1 317 ? -48.36843 -33.96460 3.69226   1.000 73.50065  ? 935  SER   A C   1 
ATOM   1993 O O   . SER   A 1 317 ? -47.30426 -33.37954 3.45957   1.000 80.08693  ? 935  SER   A O   1 
ATOM   1994 C CB  . SER   A 1 317 ? -48.19662 -35.48456 5.67158   1.000 63.65768  ? 935  SER   A CB  1 
ATOM   1995 O OG  . SER   A 1 317 ? -48.70655 -36.61586 4.99045   1.000 68.84436  ? 935  SER   A OG  1 
ATOM   1996 N N   . GLU   A 1 318 ? -49.17076 -34.40025 2.72378   1.000 71.00902  ? 936  GLU   A N   1 
ATOM   1997 C CA  . GLU   A 1 318 ? -48.88134 -34.16194 1.31721   1.000 73.14644  ? 936  GLU   A CA  1 
ATOM   1998 C C   . GLU   A 1 318 ? -49.55627 -32.87413 0.87075   1.000 71.33074  ? 936  GLU   A C   1 
ATOM   1999 O O   . GLU   A 1 318 ? -50.79323 -32.79984 0.88618   1.000 72.15647  ? 936  GLU   A O   1 
ATOM   2000 C CB  . GLU   A 1 318 ? -49.36379 -35.32014 0.46881   1.000 74.34936  ? 936  GLU   A CB  1 
ATOM   2001 N N   . PRO   A 1 319 ? -48.79776 -31.85245 0.46516   1.000 70.02583  ? 937  PRO   A N   1 
ATOM   2002 C CA  . PRO   A 1 319 ? -49.41850 -30.55093 0.16386   1.000 66.65450  ? 937  PRO   A CA  1 
ATOM   2003 C C   . PRO   A 1 319 ? -50.45078 -30.60056 -0.94753  1.000 67.98230  ? 937  PRO   A C   1 
ATOM   2004 O O   . PRO   A 1 319 ? -51.47818 -29.91780 -0.85559  1.000 66.69494  ? 937  PRO   A O   1 
ATOM   2005 C CB  . PRO   A 1 319 ? -48.21437 -29.67851 -0.22088  1.000 65.55206  ? 937  PRO   A CB  1 
ATOM   2006 C CG  . PRO   A 1 319 ? -47.03890 -30.33654 0.43969   1.000 67.99904  ? 937  PRO   A CG  1 
ATOM   2007 C CD  . PRO   A 1 319 ? -47.32770 -31.80195 0.38821   1.000 69.15318  ? 937  PRO   A CD  1 
ATOM   2008 N N   . GLU   A 1 320 ? -50.21503 -31.39501 -1.99366  1.000 66.79189  ? 938  GLU   A N   1 
ATOM   2009 C CA  . GLU   A 1 320 ? -51.13285 -31.43181 -3.12637  1.000 71.65087  ? 938  GLU   A CA  1 
ATOM   2010 C C   . GLU   A 1 320 ? -52.51442 -31.96065 -2.76172  1.000 74.23659  ? 938  GLU   A C   1 
ATOM   2011 O O   . GLU   A 1 320 ? -53.44708 -31.78849 -3.55346  1.000 74.52871  ? 938  GLU   A O   1 
ATOM   2012 C CB  . GLU   A 1 320 ? -50.54091 -32.27514 -4.25736  1.000 71.29007  ? 938  GLU   A CB  1 
ATOM   2013 N N   . LYS   A 1 321 ? -52.68237 -32.57175 -1.58818  1.000 74.20738  ? 939  LYS   A N   1 
ATOM   2014 C CA  . LYS   A 1 321 ? -53.98356 -33.08189 -1.17234  1.000 72.33450  ? 939  LYS   A CA  1 
ATOM   2015 C C   . LYS   A 1 321 ? -54.76210 -32.11135 -0.29685  1.000 67.71677  ? 939  LYS   A C   1 
ATOM   2016 O O   . LYS   A 1 321 ? -55.89697 -32.42064 0.07937   1.000 65.88466  ? 939  LYS   A O   1 
ATOM   2017 C CB  . LYS   A 1 321 ? -53.82818 -34.41321 -0.42942  1.000 73.19970  ? 939  LYS   A CB  1 
ATOM   2018 C CG  . LYS   A 1 321 ? -53.52396 -35.58980 -1.33382  1.000 82.19273  ? 939  LYS   A CG  1 
ATOM   2019 C CD  . LYS   A 1 321 ? -53.42938 -36.88110 -0.54451  1.000 86.65172  ? 939  LYS   A CD  1 
ATOM   2020 C CE  . LYS   A 1 321 ? -53.03320 -38.03098 -1.44748  1.000 96.72755  ? 939  LYS   A CE  1 
ATOM   2021 N NZ  . LYS   A 1 321 ? -52.72051 -39.26428 -0.67593  1.000 103.67295 ? 939  LYS   A NZ  1 
ATOM   2022 N N   . ARG   A 1 322 ? -54.18818 -30.95687 0.03617   1.000 61.06407  ? 940  ARG   A N   1 
ATOM   2023 C CA  . ARG   A 1 322 ? -54.93242 -29.95361 0.77596   1.000 58.99368  ? 940  ARG   A CA  1 
ATOM   2024 C C   . ARG   A 1 322 ? -55.87027 -29.19790 -0.16018  1.000 58.61362  ? 940  ARG   A C   1 
ATOM   2025 O O   . ARG   A 1 322 ? -55.55798 -29.00077 -1.33715  1.000 62.34338  ? 940  ARG   A O   1 
ATOM   2026 C CB  . ARG   A 1 322 ? -53.97965 -28.98030 1.45914   1.000 56.96114  ? 940  ARG   A CB  1 
ATOM   2027 C CG  . ARG   A 1 322 ? -53.04717 -29.65091 2.44861   1.000 56.01750  ? 940  ARG   A CG  1 
ATOM   2028 C CD  . ARG   A 1 322 ? -51.88060 -28.75657 2.80796   1.000 56.13973  ? 940  ARG   A CD  1 
ATOM   2029 N NE  . ARG   A 1 322 ? -50.82661 -29.50364 3.48373   1.000 58.63541  ? 940  ARG   A NE  1 
ATOM   2030 C CZ  . ARG   A 1 322 ? -49.55505 -29.11981 3.52806   1.000 61.09687  ? 940  ARG   A CZ  1 
ATOM   2031 N NH1 . ARG   A 1 322 ? -49.18400 -27.99978 2.92614   1.000 57.43267  ? 940  ARG   A NH1 1 
ATOM   2032 N NH2 . ARG   A 1 322 ? -48.65426 -29.85752 4.16375   1.000 62.00239  ? 940  ARG   A NH2 1 
ATOM   2033 N N   . PRO   A 1 323 ? -57.02831 -28.77505 0.33616   1.000 59.10647  ? 941  PRO   A N   1 
ATOM   2034 C CA  . PRO   A 1 323 ? -57.99663 -28.11619 -0.54032  1.000 58.33839  ? 941  PRO   A CA  1 
ATOM   2035 C C   . PRO   A 1 323 ? -57.56540 -26.70399 -0.89303  1.000 56.27035  ? 941  PRO   A C   1 
ATOM   2036 O O   . PRO   A 1 323 ? -56.83970 -26.04030 -0.14849  1.000 58.29765  ? 941  PRO   A O   1 
ATOM   2037 C CB  . PRO   A 1 323 ? -59.28122 -28.11309 0.29372   1.000 58.03248  ? 941  PRO   A CB  1 
ATOM   2038 C CG  . PRO   A 1 323 ? -58.79262 -28.10271 1.70804   1.000 56.13649  ? 941  PRO   A CG  1 
ATOM   2039 C CD  . PRO   A 1 323 ? -57.53086 -28.90791 1.71641   1.000 55.25234  ? 941  PRO   A CD  1 
ATOM   2040 N N   . SER   A 1 324 ? -58.02883 -26.24826 -2.05124  1.000 55.13813  ? 942  SER   A N   1 
ATOM   2041 C CA  . SER   A 1 324 ? -57.77515 -24.88184 -2.47108  1.000 59.95108  ? 942  SER   A CA  1 
ATOM   2042 C C   . SER   A 1 324 ? -58.54082 -23.91042 -1.57888  1.000 58.40464  ? 942  SER   A C   1 
ATOM   2043 O O   . SER   A 1 324 ? -59.52930 -24.26543 -0.93080  1.000 58.19691  ? 942  SER   A O   1 
ATOM   2044 C CB  . SER   A 1 324 ? -58.18477 -24.68629 -3.93150  1.000 65.16698  ? 942  SER   A CB  1 
ATOM   2045 O OG  . SER   A 1 324 ? -59.59344 -24.67674 -4.06921  1.000 67.91667  ? 942  SER   A OG  1 
ATOM   2046 N N   . PHE   A 1 325 ? -58.06997 -22.66437 -1.54644  1.000 56.51200  ? 943  PHE   A N   1 
ATOM   2047 C CA  . PHE   A 1 325 ? -58.79418 -21.64411 -0.79848  1.000 56.08937  ? 943  PHE   A CA  1 
ATOM   2048 C C   . PHE   A 1 325 ? -60.16867 -21.38205 -1.40072  1.000 57.48276  ? 943  PHE   A C   1 
ATOM   2049 O O   . PHE   A 1 325 ? -61.10297 -21.01074 -0.67991  1.000 54.92983  ? 943  PHE   A O   1 
ATOM   2050 C CB  . PHE   A 1 325 ? -57.97481 -20.35702 -0.73511  1.000 52.65192  ? 943  PHE   A CB  1 
ATOM   2051 C CG  . PHE   A 1 325 ? -56.89830 -20.38619 0.31160   1.000 52.59300  ? 943  PHE   A CG  1 
ATOM   2052 C CD1 . PHE   A 1 325 ? -57.22028 -20.62421 1.64247   1.000 51.62615  ? 943  PHE   A CD1 1 
ATOM   2053 C CD2 . PHE   A 1 325 ? -55.57201 -20.17839 -0.02633  1.000 51.41453  ? 943  PHE   A CD2 1 
ATOM   2054 C CE1 . PHE   A 1 325 ? -56.23975 -20.65020 2.61493   1.000 47.75268  ? 943  PHE   A CE1 1 
ATOM   2055 C CE2 . PHE   A 1 325 ? -54.58113 -20.19940 0.94423   1.000 48.30218  ? 943  PHE   A CE2 1 
ATOM   2056 C CZ  . PHE   A 1 325 ? -54.91779 -20.44043 2.26737   1.000 44.75765  ? 943  PHE   A CZ  1 
ATOM   2057 N N   . TYR   A 1 326 ? -60.31182 -21.57437 -2.71410  1.000 60.77556  ? 944  TYR   A N   1 
ATOM   2058 C CA  . TYR   A 1 326 ? -61.61674 -21.43511 -3.35321  1.000 67.88407  ? 944  TYR   A CA  1 
ATOM   2059 C C   . TYR   A 1 326 ? -62.55801 -22.54612 -2.90720  1.000 68.36964  ? 944  TYR   A C   1 
ATOM   2060 O O   . TYR   A 1 326 ? -63.68551 -22.28415 -2.46940  1.000 66.56196  ? 944  TYR   A O   1 
ATOM   2061 C CB  . TYR   A 1 326 ? -61.45083 -21.43336 -4.87474  1.000 75.29625  ? 944  TYR   A CB  1 
ATOM   2062 C CG  . TYR   A 1 326 ? -62.74479 -21.44586 -5.66173  1.000 83.78461  ? 944  TYR   A CG  1 
ATOM   2063 C CD1 . TYR   A 1 326 ? -63.22416 -22.62112 -6.23036  1.000 88.66014  ? 944  TYR   A CD1 1 
ATOM   2064 C CD2 . TYR   A 1 326 ? -63.48353 -20.28315 -5.84290  1.000 83.73552  ? 944  TYR   A CD2 1 
ATOM   2065 C CE1 . TYR   A 1 326 ? -64.40730 -22.63717 -6.95583  1.000 94.80876  ? 944  TYR   A CE1 1 
ATOM   2066 C CE2 . TYR   A 1 326 ? -64.66690 -20.29025 -6.56519  1.000 90.81326  ? 944  TYR   A CE2 1 
ATOM   2067 C CZ  . TYR   A 1 326 ? -65.12304 -21.46793 -7.11964  1.000 96.63724  ? 944  TYR   A CZ  1 
ATOM   2068 O OH  . TYR   A 1 326 ? -66.30004 -21.47667 -7.83683  1.000 101.81304 ? 944  TYR   A OH  1 
ATOM   2069 N N   . HIS   A 1 327 ? -62.10545 -23.79948 -3.01015  1.000 63.95472  ? 945  HIS   A N   1 
ATOM   2070 C CA  A HIS   A 1 327 ? -62.92275 -24.91954 -2.55363  0.522 65.69548  ? 945  HIS   A CA  1 
ATOM   2071 C CA  B HIS   A 1 327 ? -62.91882 -24.92133 -2.55368  0.478 65.67780  ? 945  HIS   A CA  1 
ATOM   2072 C C   . HIS   A 1 327 ? -63.25932 -24.78688 -1.07447  1.000 61.87237  ? 945  HIS   A C   1 
ATOM   2073 O O   . HIS   A 1 327 ? -64.37103 -25.12563 -0.65043  1.000 62.98956  ? 945  HIS   A O   1 
ATOM   2074 C CB  A HIS   A 1 327 ? -62.20522 -26.24103 -2.82818  0.522 66.66725  ? 945  HIS   A CB  1 
ATOM   2075 C CB  B HIS   A 1 327 ? -62.18679 -26.23819 -2.81773  0.478 66.60301  ? 945  HIS   A CB  1 
ATOM   2076 C CG  A HIS   A 1 327 ? -62.18839 -26.62432 -4.27472  0.522 68.10734  ? 945  HIS   A CG  1 
ATOM   2077 C CG  B HIS   A 1 327 ? -62.98743 -27.45482 -2.47639  0.478 68.29481  ? 945  HIS   A CG  1 
ATOM   2078 N ND1 A HIS   A 1 327 ? -63.28083 -26.45945 -5.09850  0.522 71.31143  ? 945  HIS   A ND1 1 
ATOM   2079 N ND1 B HIS   A 1 327 ? -64.25441 -27.67428 -2.97184  0.478 72.12033  ? 945  HIS   A ND1 1 
ATOM   2080 C CD2 A HIS   A 1 327 ? -61.21088 -27.15199 -5.04842  0.522 67.95628  ? 945  HIS   A CD2 1 
ATOM   2081 C CD2 B HIS   A 1 327 ? -62.69798 -28.52209 -1.69569  0.478 68.84754  ? 945  HIS   A CD2 1 
ATOM   2082 C CE1 A HIS   A 1 327 ? -62.97952 -26.87596 -6.31513  0.522 72.91273  ? 945  HIS   A CE1 1 
ATOM   2083 C CE1 B HIS   A 1 327 ? -64.71287 -28.82247 -2.50722  0.478 73.16018  ? 945  HIS   A CE1 1 
ATOM   2084 N NE2 A HIS   A 1 327 ? -61.72920 -27.30113 -6.31177  0.522 70.62364  ? 945  HIS   A NE2 1 
ATOM   2085 N NE2 B HIS   A 1 327 ? -63.78723 -29.35765 -1.73200  0.478 70.43267  ? 945  HIS   A NE2 1 
ATOM   2086 N N   . LEU   A 1 328 ? -62.31247 -24.29151 -0.27325  1.000 58.73302  ? 946  LEU   A N   1 
ATOM   2087 C CA  . LEU   A 1 328 ? -62.58553 -24.07026 1.14205   1.000 56.09200  ? 946  LEU   A CA  1 
ATOM   2088 C C   . LEU   A 1 328 ? -63.73432 -23.09305 1.33206   1.000 58.80553  ? 946  LEU   A C   1 
ATOM   2089 O O   . LEU   A 1 328 ? -64.59040 -23.29180 2.20292   1.000 56.81242  ? 946  LEU   A O   1 
ATOM   2090 C CB  . LEU   A 1 328 ? -61.32838 -23.56194 1.84176   1.000 53.35456  ? 946  LEU   A CB  1 
ATOM   2091 C CG  . LEU   A 1 328 ? -60.26381 -24.62571 2.12313   1.000 51.35939  ? 946  LEU   A CG  1 
ATOM   2092 C CD1 . LEU   A 1 328 ? -58.97054 -23.98292 2.59634   1.000 51.21954  ? 946  LEU   A CD1 1 
ATOM   2093 C CD2 . LEU   A 1 328 ? -60.78704 -25.60950 3.14310   1.000 50.09655  ? 946  LEU   A CD2 1 
ATOM   2094 N N   . SER   A 1 329 ? -63.77754 -22.04184 0.51030   1.000 57.76875  ? 947  SER   A N   1 
ATOM   2095 C CA  . SER   A 1 329 ? -64.86724 -21.07392 0.58522   1.000 61.13284  ? 947  SER   A CA  1 
ATOM   2096 C C   . SER   A 1 329 ? -66.21582 -21.73992 0.33862   1.000 58.69785  ? 947  SER   A C   1 
ATOM   2097 O O   . SER   A 1 329 ? -67.17500 -21.51880 1.08762   1.000 59.58491  ? 947  SER   A O   1 
ATOM   2098 C CB  . SER   A 1 329 ? -64.62998 -19.94405 -0.41991  1.000 63.44816  ? 947  SER   A CB  1 
ATOM   2099 O OG  . SER   A 1 329 ? -63.48295 -19.19129 -0.07390  1.000 65.99878  ? 947  SER   A OG  1 
ATOM   2100 N N   . GLU   A 1 330 ? -66.29905 -22.57874 -0.69790  1.000 60.23352  ? 948  GLU   A N   1 
ATOM   2101 C CA  . GLU   A 1 330 ? -67.55002 -23.26573 -1.00637  1.000 69.61607  ? 948  GLU   A CA  1 
ATOM   2102 C C   . GLU   A 1 330 ? -67.98615 -24.16359 0.14535   1.000 70.33254  ? 948  GLU   A C   1 
ATOM   2103 O O   . GLU   A 1 330 ? -69.15682 -24.15528 0.54471   1.000 72.83523  ? 948  GLU   A O   1 
ATOM   2104 C CB  . GLU   A 1 330 ? -67.39315 -24.07454 -2.29509  1.000 78.64746  ? 948  GLU   A CB  1 
ATOM   2105 C CG  . GLU   A 1 330 ? -66.63662 -23.34453 -3.39670  1.000 88.82194  ? 948  GLU   A CG  1 
ATOM   2106 C CD  . GLU   A 1 330 ? -67.49729 -22.34644 -4.14714  1.000 102.16749 ? 948  GLU   A CD  1 
ATOM   2107 O OE1 . GLU   A 1 330 ? -67.46655 -22.36242 -5.39483  1.000 108.37620 ? 948  GLU   A OE1 1 
ATOM   2108 O OE2 . GLU   A 1 330 ? -68.20932 -21.55021 -3.49925  1.000 105.49303 ? 948  GLU   A OE2 1 
ATOM   2109 N N   . ILE   A 1 331 ? -67.04922 -24.93806 0.69816   1.000 69.72162  ? 949  ILE   A N   1 
ATOM   2110 C CA  . ILE   A 1 331 ? -67.37958 -25.88143 1.76444   1.000 66.22506  ? 949  ILE   A CA  1 
ATOM   2111 C C   . ILE   A 1 331 ? -67.93095 -25.14613 2.97895   1.000 65.75036  ? 949  ILE   A C   1 
ATOM   2112 O O   . ILE   A 1 331 ? -68.95985 -25.53128 3.54730   1.000 68.08072  ? 949  ILE   A O   1 
ATOM   2113 C CB  . ILE   A 1 331 ? -66.14531 -26.72359 2.13230   1.000 67.78950  ? 949  ILE   A CB  1 
ATOM   2114 C CG1 . ILE   A 1 331 ? -65.79863 -27.69403 0.99908   1.000 72.88892  ? 949  ILE   A CG1 1 
ATOM   2115 C CG2 . ILE   A 1 331 ? -66.37545 -27.46817 3.44177   1.000 69.27193  ? 949  ILE   A CG2 1 
ATOM   2116 C CD1 . ILE   A 1 331 ? -64.58098 -28.54478 1.28340   1.000 76.79678  ? 949  ILE   A CD1 1 
ATOM   2117 N N   . VAL   A 1 332 ? -67.24591 -24.08172 3.40226   1.000 62.32130  ? 950  VAL   A N   1 
ATOM   2118 C CA  . VAL   A 1 332 ? -67.71237 -23.31070 4.55000   1.000 58.51021  ? 950  VAL   A CA  1 
ATOM   2119 C C   . VAL   A 1 332 ? -69.04497 -22.63957 4.24184   1.000 60.34109  ? 950  VAL   A C   1 
ATOM   2120 O O   . VAL   A 1 332 ? -69.88399 -22.46516 5.13407   1.000 61.20310  ? 950  VAL   A O   1 
ATOM   2121 C CB  . VAL   A 1 332 ? -66.64116 -22.28529 4.96730   1.000 56.47826  ? 950  VAL   A CB  1 
ATOM   2122 C CG1 . VAL   A 1 332 ? -67.10876 -21.47975 6.16999   1.000 52.36748  ? 950  VAL   A CG1 1 
ATOM   2123 C CG2 . VAL   A 1 332 ? -65.33480 -22.99129 5.27741   1.000 53.29598  ? 950  VAL   A CG2 1 
ATOM   2124 N N   . GLU   A 1 333 ? -69.27065 -22.27310 2.97910   1.000 63.36796  ? 951  GLU   A N   1 
ATOM   2125 C CA  . GLU   A 1 333 ? -70.52682 -21.63724 2.59688   1.000 70.57637  ? 951  GLU   A CA  1 
ATOM   2126 C C   . GLU   A 1 333 ? -71.71027 -22.56425 2.84060   1.000 69.27715  ? 951  GLU   A C   1 
ATOM   2127 O O   . GLU   A 1 333 ? -72.76750 -22.12571 3.31226   1.000 67.15857  ? 951  GLU   A O   1 
ATOM   2128 C CB  . GLU   A 1 333 ? -70.45979 -21.21594 1.12884   1.000 79.04724  ? 951  GLU   A CB  1 
ATOM   2129 C CG  . GLU   A 1 333 ? -71.41745 -20.11011 0.72923   1.000 89.03788  ? 951  GLU   A CG  1 
ATOM   2130 C CD  . GLU   A 1 333 ? -71.08914 -19.53927 -0.63444  1.000 97.50669  ? 951  GLU   A CD  1 
ATOM   2131 O OE1 . GLU   A 1 333 ? -70.62548 -20.30745 -1.50272  1.000 99.77161  ? 951  GLU   A OE1 1 
ATOM   2132 O OE2 . GLU   A 1 333 ? -71.27881 -18.32251 -0.83640  1.000 102.17616 ? 951  GLU   A OE2 1 
ATOM   2133 N N   . ASN   A 1 334 ? -71.54678 -23.85400 2.53299   1.000 67.21564  ? 952  ASN   A N   1 
ATOM   2134 C CA  . ASN   A 1 334 ? -72.62622 -24.81487 2.72951   1.000 75.63678  ? 952  ASN   A CA  1 
ATOM   2135 C C   . ASN   A 1 334 ? -72.90047 -25.08410 4.20456   1.000 73.23027  ? 952  ASN   A C   1 
ATOM   2136 O O   . ASN   A 1 334 ? -73.97963 -25.57939 4.54252   1.000 77.38185  ? 952  ASN   A O   1 
ATOM   2137 C CB  . ASN   A 1 334 ? -72.30655 -26.12357 2.00242   1.000 84.95543  ? 952  ASN   A CB  1 
ATOM   2138 C CG  . ASN   A 1 334 ? -72.30070 -25.96736 0.49111   1.000 95.28143  ? 952  ASN   A CG  1 
ATOM   2139 O OD1 . ASN   A 1 334 ? -72.77222 -24.96556 -0.04302  1.000 100.07130 ? 952  ASN   A OD1 1 
ATOM   2140 N ND2 . ASN   A 1 334 ? -71.76993 -26.96505 -0.20437  1.000 98.04615  ? 952  ASN   A ND2 1 
ATOM   2141 N N   . LEU   A 1 335 ? -71.95513 -24.77006 5.08952   1.000 70.59283  ? 953  LEU   A N   1 
ATOM   2142 C CA  . LEU   A 1 335 ? -72.21280 -24.86384 6.52065   1.000 68.31755  ? 953  LEU   A CA  1 
ATOM   2143 C C   . LEU   A 1 335 ? -73.00220 -23.67409 7.04695   1.000 69.14597  ? 953  LEU   A C   1 
ATOM   2144 O O   . LEU   A 1 335 ? -73.60617 -23.77055 8.12036   1.000 70.02554  ? 953  LEU   A O   1 
ATOM   2145 C CB  . LEU   A 1 335 ? -70.89678 -24.97776 7.29110   1.000 63.70752  ? 953  LEU   A CB  1 
ATOM   2146 C CG  . LEU   A 1 335 ? -69.98264 -26.14272 6.90975   1.000 64.19318  ? 953  LEU   A CG  1 
ATOM   2147 C CD1 . LEU   A 1 335 ? -68.88718 -26.31146 7.94550   1.000 63.78865  ? 953  LEU   A CD1 1 
ATOM   2148 C CD2 . LEU   A 1 335 ? -70.77983 -27.42886 6.74882   1.000 60.27344  ? 953  LEU   A CD2 1 
ATOM   2149 N N   . LEU   A 1 336 ? -73.01940 -22.56640 6.31664   1.000 66.42151  ? 954  LEU   A N   1 
ATOM   2150 C CA  . LEU   A 1 336 ? -73.73655 -21.39011 6.76948   1.000 66.28822  ? 954  LEU   A CA  1 
ATOM   2151 C C   . LEU   A 1 336 ? -75.21267 -21.47848 6.39563   1.000 67.73861  ? 954  LEU   A C   1 
ATOM   2152 O O   . LEU   A 1 336 ? -75.56936 -22.08819 5.38367   1.000 66.99025  ? 954  LEU   A O   1 
ATOM   2153 C CB  . LEU   A 1 336 ? -73.12428 -20.13239 6.16917   1.000 68.79872  ? 954  LEU   A CB  1 
ATOM   2154 C CG  . LEU   A 1 336 ? -71.86652 -19.65918 6.90025   1.000 65.31944  ? 954  LEU   A CG  1 
ATOM   2155 C CD1 . LEU   A 1 336 ? -71.03851 -18.74541 6.02123   1.000 64.11130  ? 954  LEU   A CD1 1 
ATOM   2156 C CD2 . LEU   A 1 336 ? -72.24012 -18.96219 8.19799   1.000 61.50488  ? 954  LEU   A CD2 1 
ATOM   2157 N N   . PRO   A 1 337 ? -76.08960 -20.90121 7.21501   1.000 68.46214  ? 955  PRO   A N   1 
ATOM   2158 C CA  . PRO   A 1 337 ? -77.51356 -20.88977 6.87339   1.000 75.73440  ? 955  PRO   A CA  1 
ATOM   2159 C C   . PRO   A 1 337 ? -77.79496 -19.95618 5.70834   1.000 83.66881  ? 955  PRO   A C   1 
ATOM   2160 O O   . PRO   A 1 337 ? -77.07379 -18.98581 5.46554   1.000 84.04862  ? 955  PRO   A O   1 
ATOM   2161 C CB  . PRO   A 1 337 ? -78.18168 -20.39495 8.16079   1.000 74.77651  ? 955  PRO   A CB  1 
ATOM   2162 C CG  . PRO   A 1 337 ? -77.13674 -19.56895 8.81882   1.000 70.62968  ? 955  PRO   A CG  1 
ATOM   2163 C CD  . PRO   A 1 337 ? -75.83149 -20.25224 8.51293   1.000 65.88230  ? 955  PRO   A CD  1 
ATOM   2164 N N   . GLY   A 1 338 ? -78.85969 -20.27054 4.97793   1.000 94.13846  ? 956  GLY   A N   1 
ATOM   2165 C CA  . GLY   A 1 338 ? -79.23657 -19.49943 3.81255   1.000 106.66336 ? 956  GLY   A CA  1 
ATOM   2166 C C   . GLY   A 1 338 ? -78.27358 -19.65164 2.65399   1.000 114.75887 ? 956  GLY   A C   1 
ATOM   2167 O O   . GLY   A 1 338 ? -77.11311 -20.03185 2.83591   1.000 113.42227 ? 956  GLY   A O   1 
ATOM   2168 N N   . GLN   A 1 339 ? -78.74774 -19.35290 1.44928   1.000 127.74928 ? 957  GLN   A N   1 
ATOM   2169 C CA  . GLN   A 1 339 ? -77.92581 -19.42689 0.25216   1.000 137.99310 ? 957  GLN   A CA  1 
ATOM   2170 C C   . GLN   A 1 339 ? -78.20120 -18.21095 -0.61331  1.000 155.00255 ? 957  GLN   A C   1 
ATOM   2171 O O   . GLN   A 1 339 ? -79.35320 -17.79744 -0.76895  1.000 156.77890 ? 957  GLN   A O   1 
ATOM   2172 C CB  . GLN   A 1 339 ? -78.19259 -20.71288 -0.53285  1.000 138.89944 ? 957  GLN   A CB  1 
ATOM   2173 C CG  . GLN   A 1 339 ? -77.28380 -21.84866 -0.11362  1.000 133.82509 ? 957  GLN   A CG  1 
ATOM   2174 C CD  . GLN   A 1 339 ? -77.91447 -23.20307 -0.30201  1.000 134.12324 ? 957  GLN   A CD  1 
ATOM   2175 O OE1 . GLN   A 1 339 ? -78.68260 -23.41790 -1.24035  1.000 136.52030 ? 957  GLN   A OE1 1 
ATOM   2176 N NE2 . GLN   A 1 339 ? -77.60089 -24.13011 0.59702   1.000 131.08498 ? 957  GLN   A NE2 1 
ATOM   2177 N N   . TYR   A 1 340 ? -77.14039 -17.63938 -1.16837  1.000 83.78759  ? 958  TYR   A N   1 
ATOM   2178 C CA  . TYR   A 1 340 ? -77.27803 -16.42957 -1.96321  1.000 94.03333  ? 958  TYR   A CA  1 
ATOM   2179 C C   . TYR   A 1 340 ? -77.77640 -16.74711 -3.36714  1.000 94.38174  ? 958  TYR   A C   1 
ATOM   2180 O O   . TYR   A 1 340 ? -78.55803 -15.98441 -3.93898  1.000 95.93673  ? 958  TYR   A O   1 
ATOM   2181 C CB  . TYR   A 1 340 ? -75.95353 -15.66876 -2.03914  1.000 103.09101 ? 958  TYR   A CB  1 
ATOM   2182 C CG  . TYR   A 1 340 ? -76.07952 -14.36737 -2.79327  1.000 112.23477 ? 958  TYR   A CG  1 
ATOM   2183 C CD1 . TYR   A 1 340 ? -76.66579 -13.25589 -2.20108  1.000 115.93541 ? 958  TYR   A CD1 1 
ATOM   2184 C CD2 . TYR   A 1 340 ? -75.63051 -14.25351 -4.10220  1.000 116.27383 ? 958  TYR   A CD2 1 
ATOM   2185 C CE1 . TYR   A 1 340 ? -76.79300 -12.06515 -2.88757  1.000 118.96052 ? 958  TYR   A CE1 1 
ATOM   2186 C CE2 . TYR   A 1 340 ? -75.75359 -13.06593 -4.79701  1.000 119.21928 ? 958  TYR   A CE2 1 
ATOM   2187 C CZ  . TYR   A 1 340 ? -76.33513 -11.97695 -4.18432  1.000 121.35658 ? 958  TYR   A CZ  1 
ATOM   2188 O OH  . TYR   A 1 340 ? -76.46048 -10.79140 -4.87261  1.000 127.06092 ? 958  TYR   A OH  1 
HETATM 2189 C C10 . A1IRC B 2 .   ? -55.88351 -1.10952  10.89792  1.000 45.72054  ? 1001 A1IRC A C10 1 
HETATM 2190 C C15 . A1IRC B 2 .   ? -55.41775 -2.31915  15.28728  1.000 64.55580  ? 1001 A1IRC A C15 1 
HETATM 2191 C C20 . A1IRC B 2 .   ? -49.21222 -6.16770  4.39564   1.000 59.70175  ? 1001 A1IRC A C20 1 
HETATM 2192 C C21 . A1IRC B 2 .   ? -50.27486 -6.95876  3.99323   1.000 61.55177  ? 1001 A1IRC A C21 1 
HETATM 2193 C C22 . A1IRC B 2 .   ? -50.03290 -8.17337  3.35048   1.000 59.16563  ? 1001 A1IRC A C22 1 
HETATM 2194 C C24 . A1IRC B 2 .   ? -47.66898 -7.78246  3.53087   1.000 61.75743  ? 1001 A1IRC A C24 1 
HETATM 2195 C C28 . A1IRC B 2 .   ? -47.81883 -11.30563 0.47153   1.000 61.52684  ? 1001 A1IRC A C28 1 
HETATM 2196 C C01 . A1IRC B 2 .   ? -50.75593 -0.92002  8.10111   1.000 56.62146  ? 1001 A1IRC A C01 1 
HETATM 2197 C C02 . A1IRC B 2 .   ? -51.56320 -1.98331  8.43868   1.000 54.88633  ? 1001 A1IRC A C02 1 
HETATM 2198 C C03 . A1IRC B 2 .   ? -51.43777 -3.20021  7.80638   1.000 53.98820  ? 1001 A1IRC A C03 1 
HETATM 2199 C C04 . A1IRC B 2 .   ? -50.48285 -3.33820  6.81486   1.000 54.73515  ? 1001 A1IRC A C04 1 
HETATM 2200 C C05 . A1IRC B 2 .   ? -49.65213 -2.28505  6.46327   1.000 53.46068  ? 1001 A1IRC A C05 1 
HETATM 2201 C C06 . A1IRC B 2 .   ? -49.79178 -1.06275  7.10889   1.000 55.96766  ? 1001 A1IRC A C06 1 
HETATM 2202 C C07 . A1IRC B 2 .   ? -52.62061 -1.84656  9.53557   1.000 50.28623  ? 1001 A1IRC A C07 1 
HETATM 2203 C C08 . A1IRC B 2 .   ? -53.46967 -1.76645  10.36238  1.000 52.03480  ? 1001 A1IRC A C08 1 
HETATM 2204 C C09 . A1IRC B 2 .   ? -54.66209 -1.61726  11.29904  1.000 47.51876  ? 1001 A1IRC A C09 1 
HETATM 2205 C C12 . A1IRC B 2 .   ? -55.94575 -1.60136  13.02068  1.000 50.57446  ? 1001 A1IRC A C12 1 
HETATM 2206 C C14 . A1IRC B 2 .   ? -56.37119 -1.79018  14.37860  1.000 57.97363  ? 1001 A1IRC A C14 1 
HETATM 2207 C C16 . A1IRC B 2 .   ? -54.12770 -2.62122  14.78676  1.000 56.64256  ? 1001 A1IRC A C16 1 
HETATM 2208 C C18 . A1IRC B 2 .   ? -50.36859 -4.71122  6.15504   1.000 54.53427  ? 1001 A1IRC A C18 1 
HETATM 2209 C C23 . A1IRC B 2 .   ? -48.72510 -8.57891  3.12009   1.000 58.95623  ? 1001 A1IRC A C23 1 
HETATM 2210 C C25 . A1IRC B 2 .   ? -47.91080 -6.57870  4.16676   1.000 61.64203  ? 1001 A1IRC A C25 1 
HETATM 2211 C C27 . A1IRC B 2 .   ? -48.21237 -9.93357  1.03044   1.000 59.53784  ? 1001 A1IRC A C27 1 
HETATM 2212 C C29 . A1IRC B 2 .   ? -48.06368 -11.46574 -1.02867  1.000 52.89182  ? 1001 A1IRC A C29 1 
HETATM 2213 C C31 . A1IRC B 2 .   ? -51.21243 -9.04145  2.91004   1.000 58.52648  ? 1001 A1IRC A C31 1 
HETATM 2214 C C35 . A1IRC B 2 .   ? -50.93817 0.40818   8.82853   1.000 60.95120  ? 1001 A1IRC A C35 1 
HETATM 2215 F F32 . A1IRC B 2 .   ? -51.12622 -10.26135 3.51557   1.000 60.72353  ? 1001 A1IRC A F32 1 
HETATM 2216 F F33 . A1IRC B 2 .   ? -51.18289 -9.19795  1.55880   1.000 58.72742  ? 1001 A1IRC A F33 1 
HETATM 2217 F F34 . A1IRC B 2 .   ? -52.39473 -8.45197  3.25739   1.000 60.61794  ? 1001 A1IRC A F34 1 
HETATM 2218 N N11 . A1IRC B 2 .   ? -56.66067 -1.11036  11.96972  1.000 49.92735  ? 1001 A1IRC A N11 1 
HETATM 2219 N N13 . A1IRC B 2 .   ? -54.74854 -1.90522  12.63776  1.000 51.54179  ? 1001 A1IRC A N13 1 
HETATM 2220 N N17 . A1IRC B 2 .   ? -53.82547 -2.41434  13.52011  1.000 53.60927  ? 1001 A1IRC A N17 1 
HETATM 2221 N N19 . A1IRC B 2 .   ? -49.40831 -4.89294  5.06973   1.000 55.82156  ? 1001 A1IRC A N19 1 
HETATM 2222 N N26 . A1IRC B 2 .   ? -48.38606 -9.82232  2.46980   1.000 60.69785  ? 1001 A1IRC A N26 1 
HETATM 2223 O O30 . A1IRC B 2 .   ? -48.37265 -9.00121  0.31622   1.000 57.01275  ? 1001 A1IRC A O30 1 
HETATM 2224 O O36 . A1IRC B 2 .   ? -51.05289 -5.59295  6.54725   1.000 56.29097  ? 1001 A1IRC A O36 1 
HETATM 2225 O O   . HOH   C 3 .   ? -75.64093 -21.82846 2.86381   1.000 69.95785  ? 1101 HOH   A O   1 
HETATM 2226 O O   . HOH   C 3 .   ? -64.289   -12.476   31.543    1.000 77.59441  ? 1102 HOH   A O   1 
HETATM 2227 O O   . HOH   C 3 .   ? -50.69154 21.82441  2.79593   1.000 72.62788  ? 1103 HOH   A O   1 
HETATM 2228 O O   . HOH   C 3 .   ? -52.37365 -15.98574 15.93199  1.000 46.82557  ? 1104 HOH   A O   1 
HETATM 2229 O O   . HOH   C 3 .   ? -46.44205 12.93616  0.63638   1.000 63.61469  ? 1105 HOH   A O   1 
HETATM 2230 O O   . HOH   C 3 .   ? -47.32605 -11.68467 4.06482   1.000 50.62383  ? 1106 HOH   A O   1 
HETATM 2231 O O   . HOH   C 3 .   ? -69.76657 -4.21192  13.75611  1.000 70.27370  ? 1107 HOH   A O   1 
HETATM 2232 O O   . HOH   C 3 .   ? -48.88884 -26.78124 12.82001  1.000 48.95487  ? 1108 HOH   A O   1 
HETATM 2233 O O   . HOH   C 3 .   ? -60.51225 -3.75416  2.50293   1.000 56.89955  ? 1109 HOH   A O   1 
HETATM 2234 O O   . HOH   C 3 .   ? -63.57168 -7.73376  -2.62797  1.000 69.05334  ? 1110 HOH   A O   1 
HETATM 2235 O O   . HOH   C 3 .   ? -59.08411 -17.69260 26.69033  1.000 60.26402  ? 1111 HOH   A O   1 
HETATM 2236 O O   . HOH   C 3 .   ? -39.86353 -14.85942 19.86482  1.000 56.83568  ? 1112 HOH   A O   1 
HETATM 2237 O O   . HOH   C 3 .   ? -51.79780 -8.90719  15.96674  1.000 54.28957  ? 1113 HOH   A O   1 
HETATM 2238 O O   . HOH   C 3 .   ? -47.01040 -20.33507 3.52971   1.000 53.92234  ? 1114 HOH   A O   1 
HETATM 2239 O O   . HOH   C 3 .   ? -63.88033 -13.49075 27.43024  1.000 61.73464  ? 1115 HOH   A O   1 
HETATM 2240 O O   . HOH   C 3 .   ? -43.46066 -4.57065  7.35957   1.000 78.39640  ? 1116 HOH   A O   1 
HETATM 2241 O O   . HOH   C 3 .   ? -70.787   -12.143   7.306     1.000 55.88963  ? 1117 HOH   A O   1 
HETATM 2242 O O   . HOH   C 3 .   ? -58.42104 -1.77764  6.44572   1.000 48.92648  ? 1118 HOH   A O   1 
HETATM 2243 O O   . HOH   C 3 .   ? -49.24254 -18.61576 6.25995   1.000 50.30893  ? 1119 HOH   A O   1 
HETATM 2244 O O   . HOH   C 3 .   ? -48.32047 -18.05151 10.65701  1.000 47.00135  ? 1120 HOH   A O   1 
HETATM 2245 O O   . HOH   C 3 .   ? -44.98972 -21.12001 16.77118  1.000 49.69386  ? 1121 HOH   A O   1 
HETATM 2246 O O   . HOH   C 3 .   ? -66.126   -12.697   1.811     1.000 50.70259  ? 1122 HOH   A O   1 
HETATM 2247 O O   . HOH   C 3 .   ? -61.69610 -14.46243 -3.38553  1.000 57.65906  ? 1123 HOH   A O   1 
HETATM 2248 O O   . HOH   C 3 .   ? -51.48280 -36.41342 6.45729   1.000 68.30454  ? 1124 HOH   A O   1 
HETATM 2249 O O   . HOH   C 3 .   ? -55.30465 -5.11390  17.61145  1.000 61.07037  ? 1125 HOH   A O   1 
HETATM 2250 O O   . HOH   C 3 .   ? -68.79503 -7.49856  18.70470  1.000 64.64678  ? 1126 HOH   A O   1 
HETATM 2251 O O   . HOH   C 3 .   ? -43.94341 -36.82827 7.31422   1.000 61.60225  ? 1127 HOH   A O   1 
HETATM 2252 O O   . HOH   C 3 .   ? -57.37686 -18.29429 -5.83620  1.000 64.44190  ? 1128 HOH   A O   1 
HETATM 2253 O O   . HOH   C 3 .   ? -51.22793 -18.05122 -1.03598  1.000 50.12950  ? 1129 HOH   A O   1 
HETATM 2254 O O   . HOH   C 3 .   ? -51.95386 -37.49946 10.40436  1.000 60.88285  ? 1130 HOH   A O   1 
HETATM 2255 O O   . HOH   C 3 .   ? -59.86688 11.83070  4.68978   1.000 49.67453  ? 1131 HOH   A O   1 
HETATM 2256 O O   . HOH   C 3 .   ? -66.91599 -12.50708 26.77745  1.000 58.41391  ? 1132 HOH   A O   1 
HETATM 2257 O O   . HOH   C 3 .   ? -60.75522 -34.45724 18.63968  1.000 64.69836  ? 1133 HOH   A O   1 
HETATM 2258 O O   . HOH   C 3 .   ? -63.17901 7.30344   10.11125  1.000 64.87962  ? 1134 HOH   A O   1 
HETATM 2259 O O   . HOH   C 3 .   ? -63.68347 -0.65618  10.92253  1.000 47.25233  ? 1135 HOH   A O   1 
HETATM 2260 O O   . HOH   C 3 .   ? -52.74300 -36.79845 16.15171  1.000 63.35406  ? 1136 HOH   A O   1 
HETATM 2261 O O   . HOH   C 3 .   ? -52.17380 -30.45230 20.95952  1.000 56.75398  ? 1137 HOH   A O   1 
HETATM 2262 O O   . HOH   C 3 .   ? -40.87993 -14.30276 10.70078  1.000 64.27413  ? 1138 HOH   A O   1 
HETATM 2263 O O   . HOH   C 3 .   ? -54.06892 -3.81559  -1.78957  1.000 65.35302  ? 1139 HOH   A O   1 
HETATM 2264 O O   . HOH   C 3 .   ? -58.23712 -4.18325  -0.01563  1.000 55.88929  ? 1140 HOH   A O   1 
HETATM 2265 O O   . HOH   C 3 .   ? -55.85861 -2.89578  -0.51626  1.000 57.78283  ? 1141 HOH   A O   1 
HETATM 2266 O O   . HOH   C 3 .   ? -52.67512 -29.77129 13.94559  1.000 48.30677  ? 1142 HOH   A O   1 
HETATM 2267 O O   . HOH   C 3 .   ? -45.53902 -14.23946 -2.66623  1.000 61.41307  ? 1143 HOH   A O   1 
HETATM 2268 O O   . HOH   C 3 .   ? -48.10408 -21.18482 -4.47268  1.000 70.51631  ? 1144 HOH   A O   1 
HETATM 2269 O O   . HOH   C 3 .   ? -55.73395 -21.77299 -3.16905  1.000 64.96484  ? 1145 HOH   A O   1 
HETATM 2270 O O   . HOH   C 3 .   ? -48.77599 -23.43346 24.74496  1.000 85.95896  ? 1146 HOH   A O   1 
HETATM 2271 O O   . HOH   C 3 .   ? -62.25932 5.12980   9.17452   1.000 60.66505  ? 1147 HOH   A O   1 
HETATM 2272 O O   . HOH   C 3 .   ? -42.46686 -22.92383 21.77958  1.000 59.70945  ? 1148 HOH   A O   1 
HETATM 2273 O O   . HOH   C 3 .   ? -60.57090 -25.72334 22.43633  1.000 59.70791  ? 1149 HOH   A O   1 
HETATM 2274 O O   . HOH   C 3 .   ? -59.43327 -28.67293 -3.30645  1.000 71.29511  ? 1150 HOH   A O   1 
HETATM 2275 O O   . HOH   C 3 .   ? -58.00018 -20.75808 -4.59509  1.000 47.16517  ? 1151 HOH   A O   1 
HETATM 2276 O O   . HOH   C 3 .   ? -43.07886 -30.84509 22.92088  1.000 73.76039  ? 1152 HOH   A O   1 
HETATM 2277 O O   . HOH   C 3 .   ? -55.21913 -30.47284 20.88089  1.000 66.72098  ? 1153 HOH   A O   1 
HETATM 2278 O O   . HOH   C 3 .   ? -53.294   -12.019   -11.201   1.000 73.02099  ? 1154 HOH   A O   1 
HETATM 2279 O O   . HOH   C 3 .   ? -46.96920 -19.76602 8.92172   1.000 62.25903  ? 1155 HOH   A O   1 
HETATM 2280 O O   . HOH   C 3 .   ? -61.98540 -12.39090 -5.40935  1.000 62.97931  ? 1156 HOH   A O   1 
HETATM 2281 O O   . HOH   C 3 .   ? -35.198   -31.611   9.304     1.000 64.92112  ? 1157 HOH   A O   1 
HETATM 2282 O O   . HOH   C 3 .   ? -66.172   -12.557   33.611    1.000 62.30452  ? 1158 HOH   A O   1 
HETATM 2283 O O   . HOH   C 3 .   ? -59.93591 -33.08042 23.08729  1.000 80.24862  ? 1159 HOH   A O   1 
HETATM 2284 O O   . HOH   C 3 .   ? -45.72361 -10.56634 -4.09266  1.000 76.64044  ? 1160 HOH   A O   1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
9    N N   . SER A 38  ? 2.14240 2.07935 1.52744 0.25758  0.31984  0.03252  584 SER A N   
10   C CA  . SER A 38  ? 1.82575 1.75124 1.26591 0.19773  0.32430  0.07009  584 SER A CA  
11   C C   . SER A 38  ? 1.63940 1.49740 1.06715 0.18425  0.26063  0.05024  584 SER A C   
12   O O   . SER A 38  ? 1.54552 1.39150 1.02675 0.13743  0.25446  0.07100  584 SER A O   
13   C CB  . SER A 38  ? 1.83017 1.75130 1.21361 0.19648  0.38344  0.12602  584 SER A CB  
14   O OG  . SER A 38  ? 1.90505 1.76672 1.14717 0.25001  0.37534  0.12177  584 SER A OG  
15   N N   . ARG A 39  ? 1.60588 1.42089 0.96899 0.22549  0.21192  0.00952  585 ARG A N   
16   C CA  . ARG A 39  ? 1.50111 1.26501 0.87079 0.21285  0.15216  -0.00959 585 ARG A CA  
17   C C   . ARG A 39  ? 1.35533 1.14115 0.84070 0.16545  0.12964  -0.02010 585 ARG A C   
18   O O   . ARG A 39  ? 1.31823 1.07939 0.83360 0.13838  0.10439  -0.01608 585 ARG A O   
19   C CB  . ARG A 39  ? 1.52102 1.24253 0.82022 0.26354  0.09892  -0.05508 585 ARG A CB  
20   N N   . TRP A 40  ? 1.28443 1.11538 0.83027 0.15942  0.13936  -0.03297 586 TRP A N   
21   C CA  . TRP A 40  ? 1.17786 1.02329 0.81807 0.12173  0.11650  -0.04340 586 TRP A CA  
22   C C   . TRP A 40  ? 1.09651 0.96454 0.79924 0.07403  0.14291  -0.01039 586 TRP A C   
23   O O   . TRP A 40  ? 0.97156 0.83464 0.73108 0.04427  0.12036  -0.01545 586 TRP A O   
24   C CB  . TRP A 40  ? 1.17572 1.05260 0.85034 0.13749  0.11188  -0.06938 586 TRP A CB  
25   C CG  . TRP A 40  ? 1.24912 1.09156 0.87454 0.18008  0.07191  -0.10894 586 TRP A CG  
26   C CD1 . TRP A 40  ? 1.32921 1.17308 0.88981 0.23168  0.07963  -0.12856 586 TRP A CD1 
27   C CD2 . TRP A 40  ? 1.24544 1.04439 0.88479 0.17583  0.01536  -0.13490 586 TRP A CD2 
28   N NE1 . TRP A 40  ? 1.38310 1.17811 0.91254 0.26014  0.02373  -0.16939 586 TRP A NE1 
29   C CE2 . TRP A 40  ? 1.33183 1.10140 0.91694 0.22287  -0.01620 -0.17194 586 TRP A CE2 
30   C CE3 . TRP A 40  ? 1.19613 0.98025 0.89196 0.13793  -0.01027 -0.12995 586 TRP A CE3 
31   C CZ2 . TRP A 40  ? 1.31951 1.04398 0.91664 0.22656  -0.07717 -0.20321 586 TRP A CZ2 
32   C CZ3 . TRP A 40  ? 1.20963 0.95909 0.92029 0.14220  -0.06187 -0.15667 586 TRP A CZ3 
33   C CH2 . TRP A 40  ? 1.25154 0.97079 0.91873 0.18296  -0.09721 -0.19252 586 TRP A CH2 
34   N N   . GLU A 41  ? 1.12886 1.01857 0.82145 0.06694  0.18932  0.02363  587 GLU A N   
35   C CA  . GLU A 41  ? 1.05169 0.96423 0.81576 0.02042  0.20965  0.05158  587 GLU A CA  
36   C C   . GLU A 41  ? 1.00294 0.86685 0.77292 -0.00725 0.18206  0.05706  587 GLU A C   
37   O O   . GLU A 41  ? 1.06889 0.88591 0.77863 0.00751  0.16690  0.05798  587 GLU A O   
38   C CB  . GLU A 41  ? 1.12679 1.06584 0.88150 0.01516  0.26489  0.09248  587 GLU A CB  
39   C CG  . GLU A 41  ? 1.11142 1.09381 0.96550 -0.03131 0.28540  0.11574  587 GLU A CG  
40   C CD  . GLU A 41  ? 1.06889 1.11782 0.99833 -0.02803 0.28544  0.09422  587 GLU A CD  
41   O OE1 . GLU A 41  ? 1.10229 1.16836 1.00031 0.01377  0.28372  0.06829  587 GLU A OE1 
42   O OE2 . GLU A 41  ? 1.01509 1.09475 1.03363 -0.06452 0.28243  0.10114  587 GLU A OE2 
43   N N   . PHE A 42  ? 0.90524 0.78017 0.74593 -0.04244 0.17262  0.05772  588 PHE A N   
44   C CA  . PHE A 42  ? 0.85891 0.69284 0.71035 -0.06493 0.14739  0.05809  588 PHE A CA  
45   C C   . PHE A 42  ? 0.91074 0.75518 0.81990 -0.10328 0.15852  0.07765  588 PHE A C   
46   O O   . PHE A 42  ? 0.87347 0.76536 0.84089 -0.11439 0.16631  0.07472  588 PHE A O   
47   C CB  . PHE A 42  ? 0.83293 0.66240 0.70487 -0.06018 0.11244  0.02764  588 PHE A CB  
48   C CG  . PHE A 42  ? 0.85125 0.64355 0.72674 -0.07394 0.09170  0.02653  588 PHE A CG  
49   C CD1 . PHE A 42  ? 0.91270 0.66771 0.74608 -0.06061 0.08099  0.02848  588 PHE A CD1 
50   C CD2 . PHE A 42  ? 0.82596 0.62054 0.74262 -0.09412 0.08114  0.02123  588 PHE A CD2 
51   C CE1 . PHE A 42  ? 0.89413 0.62106 0.73348 -0.06695 0.06479  0.02559  588 PHE A CE1 
52   C CE2 . PHE A 42  ? 0.81516 0.57582 0.72582 -0.09907 0.06571  0.01833  588 PHE A CE2 
53   C CZ  . PHE A 42  ? 0.84062 0.57066 0.71613 -0.08522 0.05976  0.02057  588 PHE A CZ  
54   N N   . PRO A 43  ? 0.95590 0.75485 0.85352 -0.12232 0.15489  0.09578  589 PRO A N   
55   C CA  . PRO A 43  ? 0.92377 0.72378 0.87909 -0.16065 0.15846  0.11274  589 PRO A CA  
56   C C   . PRO A 43  ? 0.81651 0.61958 0.81671 -0.17258 0.12594  0.08681  589 PRO A C   
57   O O   . PRO A 43  ? 0.82028 0.59980 0.79446 -0.15711 0.10190  0.06471  589 PRO A O   
58   C CB  . PRO A 43  ? 1.00123 0.73403 0.91622 -0.17029 0.15586  0.13501  589 PRO A CB  
59   C CG  . PRO A 43  ? 1.02552 0.72433 0.87614 -0.13698 0.13605  0.11677  589 PRO A CG  
60   C CD  . PRO A 43  ? 1.01251 0.75392 0.84569 -0.10766 0.14381  0.10109  589 PRO A CD  
61   N N   . ARG A 44  ? 0.84120 0.67520 0.91077 -0.19925 0.12567  0.09118  590 ARG A N   
62   C CA  . ARG A 44  ? 0.80996 0.64451 0.91338 -0.20587 0.09144  0.06596  590 ARG A CA  
63   C C   . ARG A 44  ? 0.84206 0.60791 0.91477 -0.21189 0.06211  0.05783  590 ARG A C   
64   O O   . ARG A 44  ? 0.83957 0.58939 0.89462 -0.19877 0.03748  0.03431  590 ARG A O   
65   C CB  . ARG A 44  ? 0.83846 0.72229 1.02872 -0.23141 0.09105  0.07078  590 ARG A CB  
66   C CG  . ARG A 44  ? 0.89778 0.85658 1.12287 -0.22005 0.12416  0.07811  590 ARG A CG  
67   C CD  . ARG A 44  ? 0.94486 0.96262 1.27252 -0.24475 0.12223  0.08223  590 ARG A CD  
68   N NE  . ARG A 44  ? 0.97949 1.05518 1.33667 -0.22029 0.11798  0.06055  590 ARG A NE  
69   C CZ  . ARG A 44  ? 0.95829 1.08855 1.31664 -0.19528 0.15348  0.06471  590 ARG A CZ  
70   N NH1 . ARG A 44  ? 1.00441 1.14003 1.32959 -0.19061 0.19800  0.09110  590 ARG A NH1 
71   N NH2 . ARG A 44  ? 0.86921 1.04263 1.25331 -0.17036 0.14291  0.04180  590 ARG A NH2 
72   N N   . ASP A 45  ? 0.85957 0.58039 0.92015 -0.22835 0.06575  0.07820  591 ASP A N   
73   C CA  . ASP A 45  ? 0.90729 0.55767 0.93625 -0.22877 0.03539  0.06694  591 ASP A CA  
74   C C   . ASP A 45  ? 0.91416 0.53924 0.87763 -0.19392 0.03128  0.05180  591 ASP A C   
75   O O   . ASP A 45  ? 0.98287 0.55767 0.91638 -0.18453 0.00915  0.03797  591 ASP A O   
76   C CB  . ASP A 45  ? 1.00578 0.60440 1.03835 -0.25433 0.03668  0.09332  591 ASP A CB  
77   C CG  . ASP A 45  ? 1.05799 0.64442 1.04502 -0.24396 0.06835  0.12211  591 ASP A CG  
78   O OD1 . ASP A 45  ? 1.05643 0.66596 1.00212 -0.21308 0.08167  0.11541  591 ASP A OD1 
79   O OD2 . ASP A 45  ? 1.15929 0.70708 1.15086 -0.26713 0.07679  0.15254  591 ASP A OD2 
80   N N   . GLY A 46  ? 0.86424 0.52384 0.80913 -0.17307 0.05029  0.05257  592 GLY A N   
81   C CA  . GLY A 46  ? 0.85064 0.50076 0.75682 -0.14390 0.04426  0.03770  592 GLY A CA  
82   C C   . GLY A 46  ? 0.87173 0.55405 0.79164 -0.13285 0.03733  0.01757  592 GLY A C   
83   O O   . GLY A 46  ? 0.83412 0.51836 0.73711 -0.11261 0.03585  0.00874  592 GLY A O   
84   N N   . LEU A 47  ? 0.87333 0.58024 0.82768 -0.14583 0.03162  0.01187  593 LEU A N   
85   C CA  . LEU A 47  ? 0.82895 0.56075 0.79171 -0.13500 0.02503  -0.00256 593 LEU A CA  
86   C C   . LEU A 47  ? 0.85914 0.56864 0.82007 -0.13873 0.00280  -0.01437 593 LEU A C   
87   O O   . LEU A 47  ? 0.85679 0.56858 0.84797 -0.15650 -0.01052 -0.01539 593 LEU A O   
88   C CB  . LEU A 47  ? 0.78822 0.56942 0.78501 -0.13656 0.03450  -0.00145 593 LEU A CB  
89   C CG  . LEU A 47  ? 0.78502 0.58588 0.78679 -0.12202 0.02784  -0.01363 593 LEU A CG  
90   C CD1 . LEU A 47  ? 0.74006 0.53218 0.71801 -0.10579 0.03163  -0.01579 593 LEU A CD1 
91   C CD2 . LEU A 47  ? 0.79137 0.63712 0.82836 -0.12022 0.03376  -0.01553 593 LEU A CD2 
92   N N   . VAL A 48  ? 0.87186 0.56156 0.79867 -0.12045 -0.00152 -0.02295 594 VAL A N   
93   C CA  . VAL A 48  ? 0.96120 0.62474 0.86456 -0.11341 -0.02150 -0.03533 594 VAL A CA  
94   C C   . VAL A 48  ? 0.94758 0.63658 0.85813 -0.10629 -0.02341 -0.03720 594 VAL A C   
95   O O   . VAL A 48  ? 0.98035 0.68919 0.89383 -0.09832 -0.00701 -0.03049 594 VAL A O   
96   C CB  . VAL A 48  ? 1.02393 0.64964 0.87585 -0.09145 -0.01824 -0.04031 594 VAL A CB  
97   C CG1 . VAL A 48  ? 1.08567 0.69000 0.89581 -0.07320 -0.02967 -0.05035 594 VAL A CG1 
98   C CG2 . VAL A 48  ? 1.06281 0.64550 0.90041 -0.09529 -0.02924 -0.04401 594 VAL A CG2 
99   N N   . LEU A 49  ? 0.95761 0.64189 0.87358 -0.10888 -0.04828 -0.04681 595 LEU A N   
100  C CA  . LEU A 49  ? 0.97253 0.67369 0.89272 -0.09977 -0.05641 -0.04851 595 LEU A CA  
101  C C   . LEU A 49  ? 0.99376 0.65288 0.85025 -0.07820 -0.06953 -0.05368 595 LEU A C   
102  O O   . LEU A 49  ? 1.06014 0.68242 0.88476 -0.07309 -0.09250 -0.06672 595 LEU A O   
103  C CB  . LEU A 49  ? 0.97371 0.70652 0.94981 -0.11271 -0.07732 -0.05562 595 LEU A CB  
104  C CG  . LEU A 49  ? 0.96029 0.74143 0.99731 -0.13016 -0.05804 -0.04742 595 LEU A CG  
105  C CD1 . LEU A 49  ? 1.00825 0.83200 1.11038 -0.13892 -0.07540 -0.05370 595 LEU A CD1 
106  C CD2 . LEU A 49  ? 0.89585 0.69760 0.92788 -0.11946 -0.03150 -0.03958 595 LEU A CD2 
107  N N   . GLY A 50  ? 0.93335 0.59298 0.76768 -0.06433 -0.05594 -0.04274 596 GLY A N   
108  C CA  . GLY A 50  ? 0.98696 0.60690 0.75100 -0.04067 -0.05849 -0.03979 596 GLY A CA  
109  C C   . GLY A 50  ? 1.02834 0.64057 0.77830 -0.02981 -0.07736 -0.03700 596 GLY A C   
110  O O   . GLY A 50  ? 1.03242 0.66379 0.82360 -0.03682 -0.10484 -0.04851 596 GLY A O   
111  N N   . ARG A 51  ? 1.03632 0.62194 0.73082 -0.01144 -0.06092 -0.01918 597 ARG A N   
112  C CA  . ARG A 51  ? 1.12391 0.68467 0.78347 0.00473  -0.08081 -0.01297 597 ARG A CA  
113  C C   . ARG A 51  ? 1.10573 0.69567 0.82830 -0.00745 -0.08487 -0.00763 597 ARG A C   
114  O O   . ARG A 51  ? 1.04461 0.66618 0.82078 -0.02458 -0.06266 -0.00163 597 ARG A O   
115  C CB  . ARG A 51  ? 1.23131 0.75377 0.81261 0.02614  -0.05269 0.01331  597 ARG A CB  
116  C CG  . ARG A 51  ? 1.26773 0.81428 0.88913 0.01084  -0.00857 0.04114  597 ARG A CG  
117  C CD  . ARG A 51  ? 1.39910 0.91802 0.95678 0.02814  0.02894  0.07365  597 ARG A CD  
118  N NE  . ARG A 51  ? 1.41546 0.96612 1.03575 0.00733  0.06758  0.09924  597 ARG A NE  
119  C CZ  . ARG A 51  ? 1.48006 1.02434 1.12967 -0.00541 0.07440  0.12499  597 ARG A CZ  
120  N NH1 . ARG A 51  ? 1.56777 1.07274 1.18167 0.00421  0.04797  0.13021  597 ARG A NH1 
121  N NH2 . ARG A 51  ? 1.43254 1.00625 1.15038 -0.02709 0.10290  0.14454  597 ARG A NH2 
122  N N   . VAL A 52  ? 1.09009 0.66441 0.80039 0.00665  -0.11793 -0.01250 598 VAL A N   
123  C CA  . VAL A 52  ? 1.01453 0.60939 0.77687 0.00369  -0.12712 -0.01147 598 VAL A CA  
124  C C   . VAL A 52  ? 1.06229 0.62752 0.80201 0.00550  -0.10308 0.01819  598 VAL A C   
125  O O   . VAL A 52  ? 1.12553 0.64273 0.79394 0.02076  -0.09713 0.03990  598 VAL A O   
126  C CB  . VAL A 52  ? 1.05659 0.64548 0.81821 0.02237  -0.17449 -0.02799 598 VAL A CB  
127  C CG1 . VAL A 52  ? 1.01727 0.62553 0.82981 0.02655  -0.18397 -0.02927 598 VAL A CG1 
128  C CG2 . VAL A 52  ? 1.04850 0.67175 0.85240 0.01408  -0.20009 -0.05546 598 VAL A CG2 
129  N N   . LEU A 53  ? 1.02225 0.61272 0.82129 -0.00962 -0.08981 0.02034  599 LEU A N   
130  C CA  . LEU A 53  ? 1.05197 0.61277 0.84939 -0.01313 -0.07579 0.04635  599 LEU A CA  
131  C C   . LEU A 53  ? 1.08093 0.61312 0.87761 0.00254  -0.10728 0.04564  599 LEU A C   
132  O O   . LEU A 53  ? 1.13663 0.61843 0.90197 0.00612  -0.10409 0.07365  599 LEU A O   
133  C CB  . LEU A 53  ? 0.99135 0.58361 0.85104 -0.03434 -0.05598 0.04465  599 LEU A CB  
134  C CG  . LEU A 53  ? 0.94675 0.56828 0.81371 -0.04685 -0.02813 0.04393  599 LEU A CG  
135  C CD1 . LEU A 53  ? 0.89531 0.54695 0.82222 -0.06231 -0.02016 0.03649  599 LEU A CD1 
136  C CD2 . LEU A 53  ? 0.99949 0.59678 0.82113 -0.04484 0.00107  0.07269  599 LEU A CD2 
137  N N   . GLY A 54  ? 1.07917 0.64280 0.91256 0.01291  -0.13607 0.01634  600 GLY A N   
138  C CA  . GLY A 54  ? 1.11542 0.65750 0.95166 0.03512  -0.17014 0.00988  600 GLY A CA  
139  C C   . GLY A 54  ? 1.07312 0.66962 0.95634 0.04792  -0.19620 -0.02357 600 GLY A C   
140  O O   . GLY A 54  ? 0.97374 0.62718 0.90365 0.03352  -0.18122 -0.03938 600 GLY A O   
141  N N   . SER A 55  ? 1.09168 0.67329 0.96724 0.07515  -0.23442 -0.03233 601 SER A N   
142  C CA  . SER A 55  ? 1.06706 0.71050 1.00194 0.08753  -0.25986 -0.06259 601 SER A CA  
143  C C   . SER A 55  ? 1.09747 0.73033 1.04729 0.12182  -0.29651 -0.07392 601 SER A C   
144  O O   . SER A 55  ? 1.13877 0.70011 1.02748 0.14047  -0.31817 -0.05746 601 SER A O   
145  C CB  . SER A 55  ? 1.12032 0.76837 1.03499 0.08700  -0.28075 -0.06933 601 SER A CB  
146  O OG  . SER A 55  ? 1.22617 0.80228 1.05663 0.10991  -0.30853 -0.05575 601 SER A OG  
147  N N   . GLY A 56  ? 1.05986 0.76358 1.08929 0.13260  -0.30078 -0.10019 602 GLY A N   
148  C CA  . GLY A 56  ? 1.12526 0.83852 1.18472 0.17115  -0.33809 -0.11845 602 GLY A CA  
149  C C   . GLY A 56  ? 1.12017 0.90169 1.24175 0.18135  -0.36701 -0.14017 602 GLY A C   
150  O O   . GLY A 56  ? 1.07909 0.87611 1.20144 0.15936  -0.36880 -0.13884 602 GLY A O   
151  N N   . ALA A 57  ? 1.10640 0.92976 1.28720 0.21660  -0.39268 -0.16236 603 ALA A N   
152  C CA  . ALA A 57  ? 1.09584 0.99608 1.35867 0.22721  -0.42394 -0.18416 603 ALA A CA  
153  C C   . ALA A 57  ? 1.04923 1.04400 1.39729 0.19146  -0.38719 -0.18903 603 ALA A C   
154  O O   . ALA A 57  ? 1.07185 1.11072 1.47435 0.17832  -0.41030 -0.19763 603 ALA A O   
155  C CB  . ALA A 57  ? 1.09534 1.03351 1.41677 0.27571  -0.45257 -0.20733 603 ALA A CB  
156  N N   . PHE A 58  ? 1.01403 1.03416 1.37197 0.17516  -0.33345 -0.18274 604 PHE A N   
157  C CA  . PHE A 58  ? 0.97984 1.08895 1.41724 0.14599  -0.29419 -0.18312 604 PHE A CA  
158  C C   . PHE A 58  ? 0.93490 1.02230 1.32713 0.11469  -0.24347 -0.16537 604 PHE A C   
159  O O   . PHE A 58  ? 0.87715 1.02868 1.32351 0.09167  -0.20752 -0.16114 604 PHE A O   
160  C CB  . PHE A 58  ? 0.99487 1.20242 1.52956 0.17436  -0.27915 -0.20073 604 PHE A CB  
161  N N   . GLY A 59  ? 0.95135 0.95232 1.25162 0.11292  -0.23974 -0.15290 605 GLY A N   
162  C CA  . GLY A 59  ? 0.89108 0.87174 1.15345 0.08462  -0.19941 -0.13777 605 GLY A CA  
163  C C   . GLY A 59  ? 0.89564 0.79297 1.07659 0.06785  -0.20771 -0.11943 605 GLY A C   
164  O O   . GLY A 59  ? 0.96475 0.80991 1.10383 0.08262  -0.24061 -0.11594 605 GLY A O   
165  N N   . LYS A 60  ? 0.82811 0.71432 0.98449 0.04024  -0.17576 -0.10632 606 LYS A N   
166  C CA  . LYS A 60  ? 0.85254 0.67044 0.93773 0.02689  -0.17456 -0.08775 606 LYS A CA  
167  C C   . LYS A 60  ? 0.84564 0.65831 0.91686 0.00675  -0.13799 -0.07724 606 LYS A C   
168  O O   . LYS A 60  ? 0.82768 0.68633 0.93461 -0.00102 -0.11580 -0.08336 606 LYS A O   
169  C CB  . LYS A 60  ? 0.82922 0.63729 0.89713 0.01656  -0.19209 -0.08673 606 LYS A CB  
170  C CG  . LYS A 60  ? 0.79612 0.65146 0.90933 -0.00890 -0.17732 -0.09161 606 LYS A CG  
171  C CD  . LYS A 60  ? 0.87081 0.70247 0.96323 -0.01462 -0.20724 -0.09652 606 LYS A CD  
172  C CE  . LYS A 60  ? 0.90317 0.76951 1.04370 -0.04341 -0.19785 -0.09998 606 LYS A CE  
173  N NZ  . LYS A 60  ? 0.96279 0.78841 1.06991 -0.04707 -0.23233 -0.10851 606 LYS A NZ  
174  N N   . VAL A 61  ? 0.81719 0.57420 0.83675 0.00048  -0.13164 -0.05951 607 VAL A N   
175  C CA  . VAL A 61  ? 0.83178 0.58195 0.84083 -0.01817 -0.10260 -0.04876 607 VAL A CA  
176  C C   . VAL A 61  ? 0.86542 0.59052 0.83298 -0.03009 -0.09384 -0.03445 607 VAL A C   
177  O O   . VAL A 61  ? 0.91344 0.59573 0.83562 -0.02181 -0.10290 -0.02145 607 VAL A O   
178  C CB  . VAL A 61  ? 0.83200 0.54624 0.83340 -0.01547 -0.10124 -0.04033 607 VAL A CB  
179  C CG1 . VAL A 61  ? 0.81093 0.51949 0.80792 -0.03519 -0.07663 -0.02780 607 VAL A CG1 
180  C CG2 . VAL A 61  ? 0.81114 0.54493 0.84468 0.00179  -0.11124 -0.06095 607 VAL A CG2 
181  N N   . VAL A 62  ? 0.84001 0.58662 0.81532 -0.04526 -0.07607 -0.03630 608 VAL A N   
182  C CA  . VAL A 62  ? 0.87064 0.59276 0.80456 -0.05093 -0.06862 -0.02805 608 VAL A CA  
183  C C   . VAL A 62  ? 0.82988 0.55028 0.76036 -0.06109 -0.03983 -0.01694 608 VAL A C   
184  O O   . VAL A 62  ? 0.76763 0.51328 0.73126 -0.06809 -0.02988 -0.02144 608 VAL A O   
185  C CB  . VAL A 62  ? 0.91625 0.65483 0.86209 -0.05801 -0.08117 -0.04171 608 VAL A CB  
186  C CG1 . VAL A 62  ? 0.97077 0.72438 0.94203 -0.04902 -0.11404 -0.05520 608 VAL A CG1 
187  C CG2 . VAL A 62  ? 0.87845 0.65276 0.86497 -0.07447 -0.06242 -0.04461 608 VAL A CG2 
188  N N   . GLU A 63  ? 0.85221 0.54374 0.74022 -0.05762 -0.02705 -0.00278 609 GLU A N   
189  C CA  . GLU A 63  ? 0.88475 0.58179 0.77510 -0.06398 -0.00083 0.00591  609 GLU A CA  
190  C C   . GLU A 63  ? 0.88703 0.59600 0.78013 -0.06909 -0.00063 -0.00746 609 GLU A C   
191  O O   . GLU A 63  ? 0.86146 0.56281 0.74173 -0.06831 -0.01840 -0.01898 609 GLU A O   
192  C CB  . GLU A 63  ? 1.00145 0.67066 0.84486 -0.05358 0.01760  0.02550  609 GLU A CB  
193  C CG  . GLU A 63  ? 1.16300 0.84663 1.02434 -0.05755 0.04850  0.03990  609 GLU A CG  
194  C CD  . GLU A 63  ? 1.36637 1.02913 1.18104 -0.04382 0.07451  0.06365  609 GLU A CD  
195  O OE1 . GLU A 63  ? 1.49612 1.14053 1.25232 -0.02519 0.07853  0.05765  609 GLU A OE1 
196  O OE2 . GLU A 63  ? 1.42309 1.08385 1.25634 -0.05033 0.09078  0.08913  609 GLU A OE2 
197  N N   . GLY A 64  ? 0.84322 0.56719 0.75615 -0.07466 0.01532  -0.00565 610 GLY A N   
198  C CA  . GLY A 64  ? 0.83604 0.56284 0.74902 -0.07933 0.01483  -0.01451 610 GLY A CA  
199  C C   . GLY A 64  ? 0.81736 0.54977 0.73673 -0.07700 0.03118  -0.01018 610 GLY A C   
200  O O   . GLY A 64  ? 0.72966 0.47298 0.66659 -0.07436 0.04261  -0.00134 610 GLY A O   
201  N N   . THR A 65  ? 0.82629 0.54971 0.73667 -0.07853 0.02939  -0.01571 611 THR A N   
202  C CA  . THR A 65  ? 0.81837 0.54371 0.73256 -0.07238 0.03862  -0.01403 611 THR A CA  
203  C C   . THR A 65  ? 0.84350 0.56886 0.76365 -0.08083 0.03290  -0.01566 611 THR A C   
204  O O   . THR A 65  ? 0.84720 0.55909 0.76065 -0.09143 0.02582  -0.01681 611 THR A O   
205  C CB  . THR A 65  ? 0.81399 0.51354 0.69396 -0.05712 0.04414  -0.01631 611 THR A CB  
206  O OG1 . THR A 65  ? 0.83264 0.52992 0.69336 -0.04598 0.05494  -0.01137 611 THR A OG1 
207  C CG2 . THR A 65  ? 0.77106 0.47967 0.66389 -0.04530 0.05274  -0.01500 611 THR A CG2 
208  N N   . ALA A 66  ? 0.79681 0.53606 0.73019 -0.07594 0.03501  -0.01431 612 ALA A N   
209  C CA  . ALA A 66  ? 0.78980 0.52556 0.71476 -0.07817 0.03371  -0.01164 612 ALA A CA  
210  C C   . ALA A 66  ? 0.81357 0.52888 0.72079 -0.06554 0.03179  -0.00971 612 ALA A C   
211  O O   . ALA A 66  ? 0.74970 0.47645 0.67158 -0.05216 0.02923  -0.01375 612 ALA A O   
212  C CB  . ALA A 66  ? 0.77350 0.53368 0.71171 -0.07438 0.03140  -0.01524 612 ALA A CB  
213  N N   . TYR A 67  ? 0.81689 0.50220 0.69898 -0.07018 0.03169  -0.00218 613 TYR A N   
214  C CA  . TYR A 67  ? 0.86485 0.51854 0.72197 -0.05573 0.02616  0.00088  613 TYR A CA  
215  C C   . TYR A 67  ? 0.92149 0.56821 0.75604 -0.05145 0.02638  0.01147  613 TYR A C   
216  O O   . TYR A 67  ? 0.96887 0.60806 0.79234 -0.06676 0.03673  0.02540  613 TYR A O   
217  C CB  . TYR A 67  ? 0.88087 0.48810 0.71658 -0.06186 0.02169  0.00320  613 TYR A CB  
218  C CG  . TYR A 67  ? 0.93141 0.53645 0.77001 -0.05918 0.01948  -0.00946 613 TYR A CG  
219  C CD1 . TYR A 67  ? 0.91807 0.54505 0.76449 -0.03867 0.02567  -0.01773 613 TYR A CD1 
220  C CD2 . TYR A 67  ? 0.94532 0.52760 0.77951 -0.07595 0.01106  -0.01213 613 TYR A CD2 
221  C CE1 . TYR A 67  ? 0.94482 0.56693 0.77925 -0.03093 0.02918  -0.02576 613 TYR A CE1 
222  C CE2 . TYR A 67  ? 0.98045 0.55293 0.80079 -0.06683 0.00518  -0.02565 613 TYR A CE2 
223  C CZ  . TYR A 67  ? 0.99044 0.58101 0.80334 -0.04237 0.01715  -0.03115 613 TYR A CZ  
224  O OH  . TYR A 67  ? 1.08943 0.66731 0.87437 -0.02824 0.01671  -0.04113 613 TYR A OH  
225  N N   . GLY A 68  ? 0.88939 0.53998 0.71785 -0.02908 0.01510  0.00583  614 GLY A N   
226  C CA  . GLY A 68  ? 0.95747 0.59402 0.74766 -0.01633 0.01095  0.01379  614 GLY A CA  
227  C C   . GLY A 68  ? 0.96312 0.63019 0.75438 -0.01395 0.01304  0.00801  614 GLY A C   
228  O O   . GLY A 68  ? 1.01369 0.66693 0.75868 -0.00154 0.01596  0.01655  614 GLY A O   
229  N N   . LEU A 69  ? 0.87123 0.57375 0.70652 -0.02206 0.01182  -0.00562 615 LEU A N   
230  C CA  . LEU A 69  ? 0.91373 0.63842 0.75070 -0.01521 0.00762  -0.01640 615 LEU A CA  
231  C C   . LEU A 69  ? 0.92515 0.64852 0.75939 0.00879  -0.02192 -0.03353 615 LEU A C   
232  O O   . LEU A 69  ? 1.01535 0.74000 0.82657 0.02421  -0.03197 -0.04486 615 LEU A O   
233  C CB  . LEU A 69  ? 0.91761 0.66947 0.80109 -0.03151 0.01162  -0.02369 615 LEU A CB  
234  C CG  . LEU A 69  ? 0.97121 0.74130 0.86209 -0.02526 0.00622  -0.03659 615 LEU A CG  
235  C CD1 . LEU A 69  ? 0.99720 0.77491 0.85709 -0.02159 0.02701  -0.02887 615 LEU A CD1 
236  C CD2 . LEU A 69  ? 0.97299 0.75777 0.90912 -0.04039 0.00508  -0.04034 615 LEU A CD2 
237  N N   . SER A 70  ? 0.90859 0.63063 0.76866 0.01495  -0.03856 -0.03807 616 SER A N   
238  C CA  . SER A 70  ? 0.96487 0.68594 0.83116 0.03820  -0.07352 -0.05437 616 SER A CA  
239  C C   . SER A 70  ? 0.96205 0.66395 0.81398 0.05343  -0.08164 -0.04809 616 SER A C   
240  O O   . SER A 70  ? 0.90247 0.60441 0.77192 0.04366  -0.06439 -0.03812 616 SER A O   
241  C CB  . SER A 70  ? 0.94755 0.70242 0.89498 0.02932  -0.09166 -0.06946 616 SER A CB  
242  O OG  . SER A 70  ? 1.02655 0.79138 1.01184 0.04466  -0.12199 -0.08023 616 SER A OG  
243  N N   . ARG A 71  ? 1.04689 0.72650 0.85879 0.08242  -0.11121 -0.05590 617 ARG A N   
244  C CA  . ARG A 71  ? 1.08210 0.74163 0.88287 0.10343  -0.12737 -0.05292 617 ARG A CA  
245  C C   . ARG A 71  ? 0.99926 0.70266 0.89397 0.10419  -0.14336 -0.06675 617 ARG A C   
246  O O   . ARG A 71  ? 0.96227 0.66248 0.86874 0.11518  -0.14141 -0.06224 617 ARG A O   
247  C CB  . ARG A 71  ? 1.17464 0.79640 0.90300 0.13920  -0.16048 -0.05860 617 ARG A CB  
248  N N   . SER A 72  ? 0.97073 0.71520 0.93628 0.09319  -0.15758 -0.08216 618 SER A N   
249  C CA  . SER A 72  ? 0.95877 0.75404 1.02778 0.09107  -0.16899 -0.09047 618 SER A CA  
250  C C   . SER A 72  ? 0.87119 0.69771 0.98817 0.06563  -0.12523 -0.07563 618 SER A C   
251  O O   . SER A 72  ? 0.78954 0.65366 0.97081 0.07044  -0.11676 -0.07363 618 SER A O   
252  C CB  . SER A 72  ? 0.97050 0.79034 1.10207 0.08815  -0.20877 -0.11129 618 SER A CB  
253  O OG  . SER A 72  ? 0.98361 0.80933 1.13044 0.06013  -0.19184 -0.10866 618 SER A OG  
254  N N   . GLN A 73  ? 0.86895 0.68220 0.95397 0.04293  -0.09744 -0.06563 619 GLN A N   
255  C CA  . GLN A 73  ? 0.83221 0.66348 0.94151 0.02323  -0.05952 -0.05202 619 GLN A CA  
256  C C   . GLN A 73  ? 0.80959 0.59993 0.84227 0.01873  -0.03676 -0.04146 619 GLN A C   
257  O O   . GLN A 73  ? 0.81175 0.59256 0.82154 0.00110  -0.02530 -0.03717 619 GLN A O   
258  C CB  . GLN A 73  ? 0.83205 0.68528 0.98704 -0.00118 -0.05478 -0.05052 619 GLN A CB  
259  C CG  . GLN A 73  ? 0.91862 0.79834 1.14749 -0.00347 -0.08811 -0.06296 619 GLN A CG  
260  C CD  . GLN A 73  ? 0.94101 0.82473 1.20319 -0.02843 -0.08583 -0.05970 619 GLN A CD  
261  O OE1 . GLN A 73  ? 0.92109 0.81567 1.19887 -0.04522 -0.05302 -0.04167 619 GLN A OE1 
262  N NE2 . GLN A 73  ? 0.96537 0.83245 1.22882 -0.02680 -0.12316 -0.07800 619 GLN A NE2 
263  N N   . PRO A 74  ? 0.79685 0.56140 0.79506 0.03447  -0.03302 -0.03785 620 PRO A N   
264  C CA  . PRO A 74  ? 0.81292 0.53132 0.74584 0.02639  -0.01888 -0.02764 620 PRO A CA  
265  C C   . PRO A 74  ? 0.80857 0.52962 0.74389 0.00751  0.00486  -0.02302 620 PRO A C   
266  O O   . PRO A 74  ? 0.80302 0.49122 0.69880 -0.00501 0.01105  -0.01655 620 PRO A O   
267  C CB  . PRO A 74  ? 0.84193 0.52657 0.74659 0.05045  -0.02723 -0.02711 620 PRO A CB  
268  C CG  . PRO A 74  ? 0.80801 0.53678 0.77479 0.07075  -0.03334 -0.03760 620 PRO A CG  
269  C CD  . PRO A 74  ? 0.77800 0.55162 0.79975 0.06160  -0.04623 -0.04389 620 PRO A CD  
270  N N   . VAL A 75  ? 0.76456 0.52211 0.74518 0.00528  0.01720  -0.02443 621 VAL A N   
271  C CA  . VAL A 75  ? 0.77195 0.52713 0.74281 -0.00587 0.03725  -0.01993 621 VAL A CA  
272  C C   . VAL A 75  ? 0.78529 0.57760 0.80271 -0.01993 0.04367  -0.01563 621 VAL A C   
273  O O   . VAL A 75  ? 0.81626 0.64308 0.88213 -0.01496 0.05437  -0.01121 621 VAL A O   
274  C CB  . VAL A 75  ? 0.77670 0.52609 0.73642 0.01475  0.05190  -0.02166 621 VAL A CB  
275  C CG1 . VAL A 75  ? 0.79658 0.53539 0.72946 0.00889  0.06831  -0.01874 621 VAL A CG1 
276  C CG2 . VAL A 75  ? 0.71165 0.41434 0.62737 0.03135  0.03917  -0.02764 621 VAL A CG2 
277  N N   . MET A 76  ? 0.75185 0.53785 0.76002 -0.03709 0.03812  -0.01521 622 MET A N   
278  C CA  . MET A 76  ? 0.80798 0.61761 0.85843 -0.04887 0.03647  -0.01247 622 MET A CA  
279  C C   . MET A 76  ? 0.77422 0.57196 0.80412 -0.06126 0.04371  -0.00743 622 MET A C   
280  O O   . MET A 76  ? 0.76680 0.54669 0.76251 -0.06523 0.03928  -0.01148 622 MET A O   
281  C CB  . MET A 76  ? 0.87748 0.69233 0.94587 -0.04830 0.01108  -0.02327 622 MET A CB  
282  C CG  . MET A 76  ? 0.88132 0.68195 0.92037 -0.05371 0.00300  -0.02908 622 MET A CG  
283  S SD  . MET A 76  ? 0.95074 0.75672 1.01759 -0.04781 -0.02846 -0.04523 622 MET A SD  
284  C CE  . MET A 76  ? 0.81517 0.61937 0.87395 -0.02734 -0.04693 -0.05321 622 MET A CE  
285  N N   . LYS A 77  ? 0.74431 0.55348 0.80004 -0.06702 0.05507  0.00382  623 LYS A N   
286  C CA  . LYS A 77  ? 0.75353 0.54729 0.78730 -0.07416 0.05913  0.01068  623 LYS A CA  
287  C C   . LYS A 77  ? 0.70993 0.50072 0.75700 -0.08256 0.03866  0.00281  623 LYS A C   
288  O O   . LYS A 77  ? 0.74180 0.54234 0.82820 -0.08584 0.02530  -0.00144 623 LYS A O   
289  C CB  . LYS A 77  ? 0.73834 0.54008 0.78972 -0.07532 0.08130  0.03122  623 LYS A CB  
290  C CG  . LYS A 77  ? 0.83721 0.61382 0.85008 -0.07630 0.08616  0.04204  623 LYS A CG  
291  C CD  . LYS A 77  ? 0.94306 0.72441 0.95591 -0.07193 0.11813  0.06826  623 LYS A CD  
292  C CE  . LYS A 77  ? 0.98914 0.73540 0.94525 -0.06685 0.12110  0.08083  623 LYS A CE  
293  N NZ  . LYS A 77  ? 1.02684 0.77361 0.97430 -0.06171 0.15810  0.11381  623 LYS A NZ  
294  N N   . VAL A 78  ? 0.72468 0.50211 0.74143 -0.08315 0.03280  -0.00197 624 VAL A N   
295  C CA  . VAL A 78  ? 0.76433 0.54278 0.78912 -0.08370 0.01605  -0.01243 624 VAL A CA  
296  C C   . VAL A 78  ? 0.78379 0.54925 0.79458 -0.08379 0.01179  -0.00877 624 VAL A C   
297  O O   . VAL A 78  ? 0.81751 0.56998 0.80177 -0.08274 0.01910  -0.00019 624 VAL A O   
298  C CB  . VAL A 78  ? 0.71181 0.49928 0.72186 -0.07944 0.01293  -0.02422 624 VAL A CB  
299  C CG1 . VAL A 78  ? 0.72272 0.51404 0.73454 -0.07403 0.01202  -0.02745 624 VAL A CG1 
300  C CG2 . VAL A 78  ? 0.70776 0.49057 0.69497 -0.08391 0.01970  -0.02150 624 VAL A CG2 
301  N N   . ALA A 79  ? 0.74590 0.51117 0.76931 -0.07988 -0.00368 -0.01781 625 ALA A N   
302  C CA  . ALA A 79  ? 0.74097 0.49895 0.75437 -0.07417 -0.01436 -0.02029 625 ALA A CA  
303  C C   . ALA A 79  ? 0.75835 0.54281 0.77920 -0.06676 -0.01910 -0.03692 625 ALA A C   
304  O O   . ALA A 79  ? 0.77678 0.57446 0.80447 -0.06139 -0.01751 -0.04636 625 ALA A O   
305  C CB  . ALA A 79  ? 0.66878 0.40228 0.69369 -0.07126 -0.02816 -0.01560 625 ALA A CB  
306  N N   . VAL A 80  ? 0.75769 0.55183 0.77770 -0.06470 -0.02464 -0.03979 626 VAL A N   
307  C CA  . VAL A 80  ? 0.71424 0.54576 0.75541 -0.06138 -0.02190 -0.05004 626 VAL A CA  
308  C C   . VAL A 80  ? 0.73772 0.58061 0.79755 -0.04795 -0.03963 -0.05898 626 VAL A C   
309  O O   . VAL A 80  ? 0.77389 0.60123 0.82589 -0.04859 -0.05501 -0.05605 626 VAL A O   
310  C CB  . VAL A 80  ? 0.73587 0.57751 0.77819 -0.07705 -0.01312 -0.04455 626 VAL A CB  
311  C CG1 . VAL A 80  ? 0.73148 0.61721 0.80713 -0.07886 -0.00214 -0.04745 626 VAL A CG1 
312  C CG2 . VAL A 80  ? 0.76520 0.58596 0.78298 -0.08534 -0.00034 -0.03607 626 VAL A CG2 
313  N N   . LYS A 81  ? 0.71084 0.57864 0.78991 -0.03049 -0.03965 -0.07168 627 LYS A N   
314  C CA  . LYS A 81  ? 0.74193 0.63153 0.84790 -0.01235 -0.05544 -0.08306 627 LYS A CA  
315  C C   . LYS A 81  ? 0.76919 0.71998 0.91976 -0.01673 -0.04169 -0.08512 627 LYS A C   
316  O O   . LYS A 81  ? 0.75808 0.73836 0.91516 -0.02014 -0.01484 -0.08187 627 LYS A O   
317  C CB  . LYS A 81  ? 0.74857 0.63166 0.85300 0.01548  -0.06422 -0.09865 627 LYS A CB  
318  C CG  . LYS A 81  ? 0.77836 0.68706 0.91328 0.04121  -0.08120 -0.11290 627 LYS A CG  
319  C CD  . LYS A 81  ? 0.85128 0.74066 0.97648 0.07421  -0.09481 -0.13186 627 LYS A CD  
320  C CE  . LYS A 81  ? 0.92168 0.73398 1.01557 0.07072  -0.12098 -0.12548 627 LYS A CE  
321  N NZ  . LYS A 81  ? 1.00658 0.78690 1.09285 0.10247  -0.14331 -0.14640 627 LYS A NZ  
322  N N   . MET A 82  ? 0.76491 0.73387 0.94802 -0.01644 -0.06125 -0.08877 628 MET A N   
323  C CA  . MET A 82  ? 0.80499 0.83647 1.05110 -0.02670 -0.05289 -0.08878 628 MET A CA  
324  C C   . MET A 82  ? 0.84460 0.90429 1.13681 -0.00840 -0.08299 -0.10259 628 MET A C   
325  O O   . MET A 82  ? 0.85018 0.86559 1.10979 0.00807  -0.11352 -0.10859 628 MET A O   
326  C CB  . MET A 82  ? 0.83280 0.84894 1.07714 -0.05949 -0.05322 -0.07686 628 MET A CB  
327  C CG  . MET A 82  ? 0.91555 0.87020 1.11145 -0.06149 -0.08403 -0.07779 628 MET A CG  
328  S SD  . MET A 82  ? 0.96829 0.89166 1.14596 -0.09060 -0.08753 -0.07029 628 MET A SD  
329  C CE  . MET A 82  ? 0.99790 0.98191 1.27139 -0.10858 -0.10226 -0.07596 628 MET A CE  
330  N N   . LEU A 83  ? 0.83340 0.96828 1.20524 -0.01089 -0.07386 -0.10524 629 LEU A N   
331  C CA  . LEU A 83  ? 0.81886 0.99234 1.25086 0.00750  -0.10603 -0.12031 629 LEU A CA  
332  C C   . LEU A 83  ? 0.81978 0.97538 1.26793 -0.01386 -0.14530 -0.12139 629 LEU A C   
333  O O   . LEU A 83  ? 0.80891 0.94822 1.25159 -0.04653 -0.13928 -0.11059 629 LEU A O   
334  C CB  . LEU A 83  ? 0.78938 1.06412 1.31629 0.01626  -0.07857 -0.12288 629 LEU A CB  
335  C CG  . LEU A 83  ? 0.78096 1.07973 1.29075 0.05175  -0.04488 -0.12935 629 LEU A CG  
336  C CD1 . LEU A 83  ? 0.80003 1.20816 1.41164 0.06514  -0.01862 -0.13145 629 LEU A CD1 
337  C CD2 . LEU A 83  ? 0.80043 1.04148 1.25474 0.08975  -0.07783 -0.14825 629 LEU A CD2 
338  N N   . LYS A 84  ? 0.86037 1.01194 1.32208 0.00904  -0.19045 -0.13674 630 LYS A N   
339  C CA  . LYS A 84  ? 0.95643 1.10087 1.44364 -0.00296 -0.23717 -0.14474 630 LYS A CA  
340  C C   . LYS A 84  ? 0.98154 1.22693 1.60401 -0.01593 -0.23950 -0.15093 630 LYS A C   
341  O O   . LYS A 84  ? 0.94579 1.26819 1.63510 -0.00406 -0.20570 -0.14994 630 LYS A O   
342  C CB  . LYS A 84  ? 1.02640 1.11690 1.46092 0.03133  -0.28850 -0.15725 630 LYS A CB  
343  C CG  . LYS A 84  ? 1.07290 1.06748 1.38397 0.04108  -0.28132 -0.14431 630 LYS A CG  
344  C CD  . LYS A 84  ? 1.14556 1.06496 1.38018 0.05590  -0.32945 -0.14646 630 LYS A CD  
345  C CE  . LYS A 84  ? 1.19127 1.09276 1.41413 0.09716  -0.36806 -0.15515 630 LYS A CE  
346  N NZ  . LYS A 84  ? 1.27393 1.08270 1.38910 0.11542  -0.40441 -0.14830 630 LYS A NZ  
347  N N   . PRO A 85  ? 1.05438 1.30278 1.72287 -0.04001 -0.27829 -0.15723 631 PRO A N   
348  C CA  . PRO A 85  ? 1.07965 1.43090 1.89883 -0.05608 -0.28570 -0.16200 631 PRO A CA  
349  C C   . PRO A 85  ? 1.08928 1.50758 1.97820 -0.01561 -0.30620 -0.17993 631 PRO A C   
350  O O   . PRO A 85  ? 1.05707 1.58468 2.07576 -0.01944 -0.28431 -0.17834 631 PRO A O   
351  C CB  . PRO A 85  ? 1.09726 1.41144 1.93231 -0.08192 -0.34526 -0.17348 631 PRO A CB  
352  C CG  . PRO A 85  ? 1.09786 1.30146 1.79265 -0.08845 -0.34214 -0.16653 631 PRO A CG  
353  C CD  . PRO A 85  ? 1.07776 1.23819 1.66820 -0.05316 -0.31668 -0.16103 631 PRO A CD  
354  N N   . THR A 86  ? 1.15294 1.50783 1.95810 0.02521  -0.34495 -0.19458 632 THR A N   
355  C CA  . THR A 86  ? 1.16498 1.56874 2.02533 0.07026  -0.37406 -0.21410 632 THR A CA  
356  C C   . THR A 86  ? 1.07632 1.55483 1.98246 0.09251  -0.31605 -0.21024 632 THR A C   
357  O O   . THR A 86  ? 1.05898 1.62453 2.06569 0.12184  -0.32483 -0.22518 632 THR A O   
358  C CB  . THR A 86  ? 1.28547 1.58414 2.02173 0.10884  -0.42047 -0.22295 632 THR A CB  
359  O OG1 . THR A 86  ? 1.35961 1.56683 2.00399 0.08880  -0.44978 -0.21851 632 THR A OG1 
360  C CG2 . THR A 86  ? 1.32169 1.65482 2.11830 0.15138  -0.48095 -0.24755 632 THR A CG2 
361  N N   . ALA A 87  ? 0.99642 1.44379 1.83012 0.08321  -0.25889 -0.19273 633 ALA A N   
362  C CA  . ALA A 87  ? 0.92677 1.41513 1.76297 0.11643  -0.21232 -0.19444 633 ALA A CA  
363  C C   . ALA A 87  ? 0.86835 1.49330 1.84398 0.11568  -0.17227 -0.19201 633 ALA A C   
364  O O   . ALA A 87  ? 0.80247 1.48050 1.85655 0.07122  -0.15358 -0.17521 633 ALA A O   
365  C CB  . ALA A 87  ? 0.88886 1.31365 1.62052 0.10339  -0.16618 -0.17756 633 ALA A CB  
366  N N   . ARG A 88  ? 0.93342 1.61378 1.94042 0.16659  -0.15746 -0.20758 634 ARG A N   
367  C CA  . ARG A 88  ? 0.97391 1.79301 2.11076 0.17728  -0.11046 -0.20475 634 ARG A CA  
368  C C   . ARG A 88  ? 0.98582 1.81642 2.06961 0.18185  -0.03271 -0.18776 634 ARG A C   
369  O O   . ARG A 88  ? 0.98923 1.72363 1.94965 0.17042  -0.02249 -0.17943 634 ARG A O   
370  C CB  . ARG A 88  ? 1.05412 1.93169 2.25539 0.23908  -0.13933 -0.23463 634 ARG A CB  
371  C CG  . ARG A 88  ? 1.14303 1.95510 2.32482 0.25438  -0.22707 -0.25608 634 ARG A CG  
372  C CD  . ARG A 88  ? 1.23612 2.06142 2.42442 0.32766  -0.25397 -0.28589 634 ARG A CD  
373  N NE  . ARG A 88  ? 1.30583 2.02613 2.35183 0.36083  -0.24548 -0.29168 634 ARG A NE  
374  C CZ  . ARG A 88  ? 1.36989 1.98781 2.33045 0.39570  -0.30175 -0.30674 634 ARG A CZ  
375  N NH1 . ARG A 88  ? 1.40056 2.00583 2.39096 0.40798  -0.37003 -0.31804 634 ARG A NH1 
376  N NH2 . ARG A 88  ? 1.41657 1.94088 2.26206 0.41877  -0.29279 -0.30979 634 ARG A NH2 
377  N N   . SER A 89  ? 1.08578 1.41764 2.14193 -0.11626 0.16369  -0.18468 635 SER A N   
378  C CA  . SER A 89  ? 1.10982 1.42271 2.10332 -0.10932 0.21702  -0.19307 635 SER A CA  
379  C C   . SER A 89  ? 1.08548 1.37332 2.06374 -0.05842 0.20382  -0.20581 635 SER A C   
380  O O   . SER A 89  ? 1.07646 1.31436 1.96408 -0.05416 0.22990  -0.19920 635 SER A O   
381  C CB  . SER A 89  ? 1.12185 1.52668 2.17931 -0.12908 0.27044  -0.22143 635 SER A CB  
382  O OG  . SER A 89  ? 1.07872 1.57160 2.26098 -0.09508 0.25870  -0.25640 635 SER A OG  
383  N N   . SER A 90  ? 1.09572 1.41639 2.16039 -0.02140 0.16276  -0.22251 636 SER A N   
384  C CA  . SER A 90  ? 1.15086 1.43979 2.19995 0.02466  0.15001  -0.23658 636 SER A CA  
385  C C   . SER A 90  ? 1.20255 1.39024 2.13308 0.02647  0.12293  -0.20695 636 SER A C   
386  O O   . SER A 90  ? 1.20681 1.35560 2.06901 0.04423  0.13875  -0.21184 636 SER A O   
387  C CB  . SER A 90  ? 1.10695 1.43741 2.27285 0.06310  0.10389  -0.25375 636 SER A CB  
388  O OG  . SER A 90  ? 1.06651 1.35388 2.22205 0.05936  0.03803  -0.22357 636 SER A OG  
389  N N   . GLU A 91  ? 1.23790 1.38721 2.14324 0.00463  0.08379  -0.17849 637 GLU A N   
390  C CA  . GLU A 91  ? 1.25325 1.31399 2.05488 0.00320  0.05869  -0.15388 637 GLU A CA  
391  C C   . GLU A 91  ? 1.23744 1.25400 1.94189 -0.02013 0.10109  -0.13529 637 GLU A C   
392  O O   . GLU A 91  ? 1.32654 1.27892 1.94531 -0.01226 0.09201  -0.12008 637 GLU A O   
393  C CB  . GLU A 91  ? 1.32203 1.36305 2.13610 -0.01672 0.00432  -0.13544 637 GLU A CB  
394  C CG  . GLU A 91  ? 1.38586 1.46320 2.29089 0.00825  -0.04719 -0.14545 637 GLU A CG  
395  C CD  . GLU A 91  ? 1.42455 1.51292 2.36439 -0.02298 -0.09655 -0.12757 637 GLU A CD  
396  O OE1 . GLU A 91  ? 1.43193 1.56498 2.40743 -0.05852 -0.07961 -0.12463 637 GLU A OE1 
397  O OE2 . GLU A 91  ? 1.43726 1.49019 2.36457 -0.01677 -0.15262 -0.11647 637 GLU A OE2 
398  N N   . LYS A 92  ? 1.14739 1.19812 1.86519 -0.04884 0.14608  -0.13517 638 LYS A N   
399  C CA  . LYS A 92  ? 1.07546 1.08322 1.70487 -0.06933 0.18733  -0.11426 638 LYS A CA  
400  C C   . LYS A 92  ? 1.03908 1.05660 1.62991 -0.05092 0.22136  -0.12458 638 LYS A C   
401  O O   . LYS A 92  ? 1.07818 1.04376 1.57856 -0.05117 0.23295  -0.10207 638 LYS A O   
402  C CB  . LYS A 92  ? 1.04945 1.08301 1.69955 -0.11305 0.22238  -0.10865 638 LYS A CB  
403  N N   . GLN A 93  ? 0.98535 1.07250 1.64635 -0.03658 0.23833  -0.15940 639 GLN A N   
404  C CA  . GLN A 93  ? 0.97849 1.07847 1.60317 -0.02362 0.27233  -0.17645 639 GLN A CA  
405  C C   . GLN A 93  ? 0.95488 1.00073 1.51940 0.00770  0.24156  -0.17178 639 GLN A C   
406  O O   . GLN A 93  ? 0.94058 0.96358 1.42308 0.00658  0.26270  -0.16375 639 GLN A O   
407  C CB  . GLN A 93  ? 0.93684 1.12321 1.66253 -0.01241 0.29672  -0.22305 639 GLN A CB  
408  N N   . ALA A 94  ? 0.91229 0.93864 1.51252 0.03127  0.18987  -0.17485 640 ALA A N   
409  C CA  . ALA A 94  ? 0.91648 0.89178 1.46004 0.05694  0.15885  -0.17293 640 ALA A CA  
410  C C   . ALA A 94  ? 0.95611 0.86711 1.39472 0.04451  0.15081  -0.13616 640 ALA A C   
411  O O   . ALA A 94  ? 0.97936 0.86048 1.34751 0.05697  0.14723  -0.13293 640 ALA A O   
412  C CB  . ALA A 94  ? 0.85723 0.82375 1.46129 0.07838  0.10281  -0.18108 640 ALA A CB  
413  N N   . LEU A 95  ? 0.99407 0.88474 1.42413 0.01970  0.14906  -0.10999 641 LEU A N   
414  C CA  . LEU A 95  ? 0.97863 0.80885 1.32216 0.01172  0.14413  -0.07698 641 LEU A CA  
415  C C   . LEU A 95  ? 1.04253 0.87129 1.32037 0.00433  0.18590  -0.06024 641 LEU A C   
416  O O   . LEU A 95  ? 1.05997 0.85403 1.26406 0.01323  0.17923  -0.04101 641 LEU A O   
417  C CB  . LEU A 95  ? 0.96759 0.77179 1.32430 -0.01418 0.13592  -0.05816 641 LEU A CB  
418  C CG  . LEU A 95  ? 0.94153 0.67959 1.23030 -0.01673 0.12024  -0.03208 641 LEU A CG  
419  C CD1 . LEU A 95  ? 0.94081 0.65836 1.21015 0.00308  0.07555  -0.04166 641 LEU A CD1 
420  C CD2 . LEU A 95  ? 0.90682 0.61903 1.21339 -0.04716 0.12140  -0.02061 641 LEU A CD2 
421  N N   . MET A 96  ? 1.05649 0.92715 1.35910 -0.01514 0.22786  -0.06635 642 MET A N   
422  C CA  . MET A 96  ? 1.08576 0.95763 1.32083 -0.02959 0.26635  -0.04812 642 MET A CA  
423  C C   . MET A 96  ? 1.05618 0.94741 1.25417 -0.01242 0.27114  -0.06651 642 MET A C   
424  O O   . MET A 96  ? 1.05617 0.92804 1.17231 -0.01624 0.27861  -0.04168 642 MET A O   
425  C CB  . MET A 96  ? 1.16576 1.08177 1.43420 -0.06184 0.31114  -0.05486 642 MET A CB  
426  C CG  . MET A 96  ? 1.29866 1.21773 1.49304 -0.08640 0.35133  -0.03383 642 MET A CG  
427  S SD  . MET A 96  ? 1.38745 1.22555 1.48034 -0.08679 0.33630  0.02855  642 MET A SD  
428  C CE  . MET A 96  ? 1.35420 1.14315 1.48354 -0.10078 0.32721  0.04851  642 MET A CE  
429  N N   . SER A 97  ? 1.03887 0.96745 1.29741 0.00595  0.26599  -0.10943 643 SER A N   
430  C CA  . SER A 97  ? 1.09379 1.03398 1.31823 0.02055  0.27238  -0.13310 643 SER A CA  
431  C C   . SER A 97  ? 1.05156 0.93976 1.21214 0.03944  0.23163  -0.11608 643 SER A C   
432  O O   . SER A 97  ? 1.07862 0.96274 1.16498 0.03793  0.23992  -0.11171 643 SER A O   
433  C CB  . SER A 97  ? 1.11167 1.09592 1.42744 0.03939  0.27663  -0.18468 643 SER A CB  
434  O OG  . SER A 97  ? 1.10330 1.07074 1.48532 0.06096  0.23018  -0.18856 643 SER A OG  
435  N N   . GLU A 98  ? 1.02073 0.87381 1.20674 0.05232  0.18799  -0.10766 644 GLU A N   
436  C CA  . GLU A 98  ? 1.00353 0.81023 1.12879 0.06461  0.15054  -0.09236 644 GLU A CA  
437  C C   . GLU A 98  ? 1.00145 0.78786 1.04407 0.05352  0.16112  -0.05251 644 GLU A C   
438  O O   . GLU A 98  ? 0.98920 0.76670 0.96486 0.05956  0.15248  -0.04582 644 GLU A O   
439  C CB  . GLU A 98  ? 1.00330 0.77901 1.16726 0.06895  0.10728  -0.08810 644 GLU A CB  
440  C CG  . GLU A 98  ? 1.04724 0.77780 1.15008 0.07496  0.07086  -0.07384 644 GLU A CG  
441  C CD  . GLU A 98  ? 1.04502 0.74812 1.18134 0.06970  0.03157  -0.07240 644 GLU A CD  
442  O OE1 . GLU A 98  ? 1.03737 0.75884 1.24685 0.06458  0.02619  -0.08354 644 GLU A OE1 
443  O OE2 . GLU A 98  ? 1.02127 0.68975 1.11137 0.06743  0.00637  -0.06113 644 GLU A OE2 
444  N N   . LEU A 99  ? 0.97411 0.75291 1.02202 0.03664  0.17882  -0.02431 645 LEU A N   
445  C CA  . LEU A 99  ? 0.93442 0.69186 0.91268 0.02854  0.18892  0.01853  645 LEU A CA  
446  C C   . LEU A 99  ? 0.93622 0.72740 0.85771 0.01843  0.21695  0.02112  645 LEU A C   
447  O O   . LEU A 99  ? 0.92858 0.71208 0.78106 0.02146  0.20802  0.04599  645 LEU A O   
448  C CB  . LEU A 99  ? 0.89397 0.63116 0.89244 0.00966  0.20726  0.04575  645 LEU A CB  
449  C CG  . LEU A 99  ? 0.96237 0.67051 0.89804 0.00228  0.21826  0.09572  645 LEU A CG  
450  C CD1 . LEU A 99  ? 0.92148 0.59204 0.82620 0.02448  0.18455  0.11581  645 LEU A CD1 
451  C CD2 . LEU A 99  ? 0.99830 0.68167 0.95604 -0.02059 0.24180  0.11759  645 LEU A CD2 
452  N N   . LYS A 100 ? 0.93403 0.76877 0.88510 0.00336  0.25162  -0.00652 646 LYS A N   
453  C CA  . LYS A 100 ? 1.00421 0.87558 0.89930 -0.01517 0.28363  -0.01065 646 LYS A CA  
454  C C   . LYS A 100 ? 1.01917 0.89498 0.87047 -0.00086 0.26714  -0.03048 646 LYS A C   
455  O O   . LYS A 100 ? 1.10041 0.98693 0.87223 -0.01463 0.27431  -0.01095 646 LYS A O   
456  C CB  . LYS A 100 ? 0.97409 0.89641 0.92212 -0.03391 0.32622  -0.04946 646 LYS A CB  
457  N N   . ILE A 101 ? 0.94157 0.80857 0.84051 0.02338  0.24346  -0.06728 647 ILE A N   
458  C CA  . ILE A 101 ? 0.96895 0.83188 0.82419 0.03415  0.22791  -0.08861 647 ILE A CA  
459  C C   . ILE A 101 ? 0.97433 0.80771 0.76042 0.03970  0.19398  -0.05030 647 ILE A C   
460  O O   . ILE A 101 ? 0.91814 0.76320 0.63111 0.03183  0.19420  -0.04626 647 ILE A O   
461  C CB  . ILE A 101 ? 0.94890 0.79968 0.87362 0.05834  0.20680  -0.13222 647 ILE A CB  
462  C CG1 . ILE A 101 ? 0.97568 0.86655 0.97802 0.05690  0.24286  -0.17387 647 ILE A CG1 
463  C CG2 . ILE A 101 ? 0.98606 0.81862 0.85834 0.06713  0.18720  -0.15144 647 ILE A CG2 
464  C CD1 . ILE A 101 ? 0.97330 0.85343 1.05568 0.08483  0.21986  -0.21293 647 ILE A CD1 
465  N N   . MET A 102 ? 0.92546 0.72488 0.73536 0.05084  0.16631  -0.02396 648 MET A N   
466  C CA  . MET A 102 ? 0.98031 0.75634 0.73859 0.05876  0.13573  0.00734  648 MET A CA  
467  C C   . MET A 102 ? 1.04368 0.83658 0.73662 0.04562  0.15040  0.05125  648 MET A C   
468  O O   . MET A 102 ? 1.09005 0.88947 0.72452 0.04842  0.13239  0.06812  648 MET A O   
469  C CB  . MET A 102 ? 0.97172 0.70914 0.77463 0.06913  0.11103  0.02136  648 MET A CB  
470  C CG  . MET A 102 ? 1.00275 0.72085 0.85057 0.07902  0.08168  -0.01302 648 MET A CG  
471  S SD  . MET A 102 ? 1.03938 0.71564 0.92334 0.08010  0.05407  0.00171  648 MET A SD  
472  C CE  . MET A 102 ? 1.06088 0.72258 0.88295 0.08756  0.01946  0.00450  648 MET A CE  
473  N N   . THR A 103 ? 1.05026 0.85239 0.75098 0.02871  0.18087  0.07261  649 THR A N   
474  C CA  . THR A 103 ? 1.14570 0.96179 0.78073 0.01247  0.19162  0.12015  649 THR A CA  
475  C C   . THR A 103 ? 1.25435 1.11458 0.82092 -0.00571 0.20291  0.10712  649 THR A C   
476  O O   . THR A 103 ? 1.35299 1.22873 0.85303 -0.01327 0.19220  0.14476  649 THR A O   
477  C CB  . THR A 103 ? 1.16840 0.98307 0.81848 -0.01003 0.22419  0.14234  649 THR A CB  
478  O OG1 . THR A 103 ? 1.22329 1.07230 0.90138 -0.02854 0.25847  0.09708  649 THR A OG1 
479  C CG2 . THR A 103 ? 1.09062 0.85755 0.79880 0.00257  0.21502  0.15828  649 THR A CG2 
480  N N   . HIS A 104 ? 1.28533 1.16749 0.86985 -0.01355 0.22454  0.05323  650 HIS A N   
481  C CA  . HIS A 104 ? 1.38705 1.30950 0.90866 -0.03768 0.24539  0.03120  650 HIS A CA  
482  C C   . HIS A 104 ? 1.33604 1.25440 0.82398 -0.02521 0.21871  0.00803  650 HIS A C   
483  O O   . HIS A 104 ? 1.42558 1.37517 0.84624 -0.04874 0.23220  -0.00430 650 HIS A O   
484  C CB  . HIS A 104 ? 1.46591 1.41425 1.02835 -0.05373 0.28951  -0.02100 650 HIS A CB  
485  C CG  . HIS A 104 ? 1.59331 1.55721 1.17351 -0.07794 0.32247  -0.00215 650 HIS A CG  
486  N ND1 . HIS A 104 ? 1.65247 1.61265 1.18062 -0.09696 0.32018  0.05978  650 HIS A ND1 
487  C CD2 . HIS A 104 ? 1.61978 1.60298 1.26485 -0.08760 0.35758  -0.03608 650 HIS A CD2 
488  C CE1 . HIS A 104 ? 1.68949 1.66037 1.24108 -0.12127 0.35336  0.06333  650 HIS A CE1 
489  N NE2 . HIS A 104 ? 1.66195 1.65176 1.28531 -0.11698 0.37769  0.00391  650 HIS A NE2 
490  N N   . LEU A 105 ? 1.19866 1.07986 0.72539 0.00496  0.18256  0.00077  651 LEU A N   
491  C CA  . LEU A 105 ? 1.13422 1.00966 0.61771 0.01131  0.15472  -0.01485 651 LEU A CA  
492  C C   . LEU A 105 ? 1.15652 1.05426 0.56745 0.00348  0.13577  0.03228  651 LEU A C   
493  O O   . LEU A 105 ? 1.15303 1.07396 0.49802 -0.01066 0.12978  0.02269  651 LEU A O   
494  C CB  . LEU A 105 ? 1.01520 0.84627 0.55265 0.03858  0.11957  -0.03155 651 LEU A CB  
495  C CG  . LEU A 105 ? 0.99603 0.80509 0.60530 0.05000  0.12451  -0.07836 651 LEU A CG  
496  C CD1 . LEU A 105 ? 0.93373 0.70012 0.58043 0.06926  0.08216  -0.08341 651 LEU A CD1 
497  C CD2 . LEU A 105 ? 0.92272 0.74206 0.50558 0.04026  0.14410  -0.12433 651 LEU A CD2 
498  N N   . GLY A 106 ? 1.06255 0.78643 0.65824 0.01655  0.07599  0.06950  652 GLY A N   
499  C CA  . GLY A 106 ? 1.02476 0.75371 0.59675 0.01582  0.03710  0.08825  652 GLY A CA  
500  C C   . GLY A 106 ? 0.94463 0.70946 0.57397 0.02850  0.00974  0.08518  652 GLY A C   
501  O O   . GLY A 106 ? 0.90251 0.68358 0.57681 0.03520  0.01932  0.06809  652 GLY A O   
502  N N   . PRO A 107 ? 0.95046 0.72943 0.58122 0.03272  -0.02364 0.10423  653 PRO A N   
503  C CA  . PRO A 107 ? 0.90886 0.72189 0.59807 0.04558  -0.04474 0.10294  653 PRO A CA  
504  C C   . PRO A 107 ? 0.92534 0.75251 0.60550 0.03603  -0.06099 0.08916  653 PRO A C   
505  O O   . PRO A 107 ? 1.01545 0.83026 0.63835 0.01774  -0.07097 0.08764  653 PRO A O   
506  C CB  . PRO A 107 ? 0.89770 0.71849 0.59668 0.05569  -0.06845 0.13259  653 PRO A CB  
507  C CG  . PRO A 107 ? 0.95788 0.75675 0.58496 0.04127  -0.07692 0.14964  653 PRO A CG  
508  C CD  . PRO A 107 ? 0.96980 0.73567 0.55391 0.02792  -0.04171 0.13209  653 PRO A CD  
509  N N   . HIS A 108 ? 0.85154 0.70232 0.58542 0.04567  -0.06265 0.07832  654 HIS A N   
510  C CA  . HIS A 108 ? 0.82738 0.69543 0.56722 0.03827  -0.07953 0.06887  654 HIS A CA  
511  C C   . HIS A 108 ? 0.77716 0.67673 0.58218 0.05412  -0.08798 0.07195  654 HIS A C   
512  O O   . HIS A 108 ? 0.75895 0.66004 0.59772 0.06701  -0.07276 0.06962  654 HIS A O   
513  C CB  . HIS A 108 ? 0.83975 0.68745 0.56037 0.02789  -0.05791 0.04416  654 HIS A CB  
514  C CG  . HIS A 108 ? 0.82303 0.67919 0.54137 0.01517  -0.07285 0.03364  654 HIS A CG  
515  N ND1 . HIS A 108 ? 0.75297 0.63060 0.52233 0.02383  -0.07475 0.02894  654 HIS A ND1 
516  C CD2 . HIS A 108 ? 0.85987 0.70467 0.52818 -0.00923 -0.08653 0.02668  654 HIS A CD2 
517  C CE1 . HIS A 108 ? 0.79636 0.67525 0.55271 0.00649  -0.08694 0.02014  654 HIS A CE1 
518  N NE2 . HIS A 108 ? 0.85652 0.71632 0.55216 -0.01506 -0.09537 0.01735  654 HIS A NE2 
519  N N   . LEU A 109 ? 0.74308 0.66829 0.56376 0.05015  -0.11147 0.07646  655 LEU A N   
520  C CA  . LEU A 109 ? 0.73047 0.68514 0.61085 0.06457  -0.11650 0.08084  655 LEU A CA  
521  C C   . LEU A 109 ? 0.70137 0.65337 0.60586 0.07005  -0.09583 0.06339  655 LEU A C   
522  O O   . LEU A 109 ? 0.70122 0.66520 0.64339 0.08292  -0.09010 0.06501  655 LEU A O   
523  C CB  . LEU A 109 ? 0.85743 0.84350 0.75359 0.05535  -0.14200 0.08689  655 LEU A CB  
524  C CG  . LEU A 109 ? 0.89875 0.91546 0.85633 0.06700  -0.14148 0.08810  655 LEU A CG  
525  C CD1 . LEU A 109 ? 0.87678 0.91100 0.87544 0.08756  -0.14577 0.10984  655 LEU A CD1 
526  C CD2 . LEU A 109 ? 0.95596 0.99834 0.92480 0.04981  -0.15828 0.08456  655 LEU A CD2 
527  N N   . ASN A 110 ? 0.68025 0.61467 0.56179 0.06027  -0.08349 0.04773  656 ASN A N   
528  C CA  . ASN A 110 ? 0.67705 0.61253 0.58266 0.06556  -0.06837 0.03683  656 ASN A CA  
529  C C   . ASN A 110 ? 0.71724 0.63836 0.62187 0.07187  -0.04739 0.03267  656 ASN A C   
530  O O   . ASN A 110 ? 0.63769 0.55773 0.55653 0.07512  -0.03517 0.02653  656 ASN A O   
531  C CB  . ASN A 110 ? 0.64724 0.57479 0.54126 0.05270  -0.06795 0.02577  656 ASN A CB  
532  C CG  . ASN A 110 ? 0.66481 0.61633 0.57332 0.04394  -0.08912 0.03022  656 ASN A CG  
533  O OD1 . ASN A 110 ? 0.70267 0.64921 0.58505 0.02489  -0.10060 0.02568  656 ASN A OD1 
534  N ND2 . ASN A 110 ? 0.60055 0.57885 0.55103 0.05561  -0.09307 0.03836  656 ASN A ND2 
535  N N   . ILE A 111 ? 0.78529 0.69755 0.67749 0.07350  -0.04314 0.03876  657 ILE A N   
536  C CA  . ILE A 111 ? 0.71588 0.62296 0.61787 0.07763  -0.02449 0.03716  657 ILE A CA  
537  C C   . ILE A 111 ? 0.65272 0.56738 0.57376 0.08298  -0.02825 0.04485  657 ILE A C   
538  O O   . ILE A 111 ? 0.61315 0.52612 0.52908 0.08526  -0.03992 0.05428  657 ILE A O   
539  C CB  . ILE A 111 ? 0.82850 0.70994 0.69392 0.07031  -0.00802 0.03510  657 ILE A CB  
540  C CG1 . ILE A 111 ? 0.77485 0.63773 0.61155 0.06199  -0.00092 0.02356  657 ILE A CG1 
541  C CG2 . ILE A 111 ? 0.86677 0.75019 0.75443 0.07394  0.01379  0.03436  657 ILE A CG2 
542  C CD1 . ILE A 111 ? 0.68645 0.55384 0.55506 0.06945  0.01314  0.01621  657 ILE A CD1 
543  N N   . VAL A 112 ? 0.61846 0.54165 0.56396 0.08427  -0.01840 0.04159  658 VAL A N   
544  C CA  . VAL A 112 ? 0.64627 0.56795 0.60405 0.08432  -0.01782 0.04437  658 VAL A CA  
545  C C   . VAL A 112 ? 0.72001 0.61801 0.65485 0.08257  -0.01298 0.05421  658 VAL A C   
546  O O   . VAL A 112 ? 0.76094 0.64661 0.67247 0.07765  -0.00351 0.05620  658 VAL A O   
547  C CB  . VAL A 112 ? 0.63996 0.57599 0.62217 0.07868  -0.01014 0.03847  658 VAL A CB  
548  C CG1 . VAL A 112 ? 0.58593 0.54361 0.58488 0.08008  -0.01934 0.03350  658 VAL A CG1 
549  C CG2 . VAL A 112 ? 0.62542 0.56511 0.61230 0.07582  0.00369  0.03913  658 VAL A CG2 
550  N N   . ASN A 113 ? 0.68831 0.57628 0.62800 0.08727  -0.01672 0.06158  659 ASN A N   
551  C CA  . ASN A 113 ? 0.85708 0.72155 0.77549 0.08953  -0.01660 0.07813  659 ASN A CA  
552  C C   . ASN A 113 ? 0.83230 0.67547 0.75202 0.08242  0.00204  0.07868  659 ASN A C   
553  O O   . ASN A 113 ? 0.78115 0.61516 0.72071 0.08265  0.00829  0.07499  659 ASN A O   
554  C CB  . ASN A 113 ? 0.92067 0.78643 0.85379 0.10249  -0.02897 0.09029  659 ASN A CB  
555  C CG  . ASN A 113 ? 0.96681 0.81189 0.88172 0.10813  -0.03329 0.11476  659 ASN A CG  
556  O OD1 . ASN A 113 ? 1.06619 0.90014 0.94334 0.10025  -0.03453 0.12313  659 ASN A OD1 
557  N ND2 . ASN A 113 ? 0.85875 0.69617 0.79928 0.12248  -0.03351 0.12790  659 ASN A ND2 
558  N N   . LEU A 114 ? 0.81450 0.64662 0.71130 0.07378  0.01403  0.08182  660 LEU A N   
559  C CA  . LEU A 114 ? 0.81982 0.63190 0.71870 0.06404  0.03388  0.08432  660 LEU A CA  
560  C C   . LEU A 114 ? 0.83368 0.61212 0.71917 0.06995  0.03440  0.10342  660 LEU A C   
561  O O   . LEU A 114 ? 0.90815 0.67475 0.76235 0.07642  0.02482  0.12238  660 LEU A O   
562  C CB  . LEU A 114 ? 0.84845 0.65619 0.72625 0.05436  0.05134  0.08484  660 LEU A CB  
563  C CG  . LEU A 114 ? 0.92370 0.70915 0.80159 0.04217  0.07455  0.09094  660 LEU A CG  
564  C CD1 . LEU A 114 ? 0.90719 0.71201 0.83307 0.03136  0.08105  0.07697  660 LEU A CD1 
565  C CD2 . LEU A 114 ? 0.95950 0.73510 0.80873 0.03397  0.09636  0.09443  660 LEU A CD2 
566  N N   . LEU A 115 ? 0.77208 0.53343 0.67996 0.06664  0.04540  0.09949  661 LEU A N   
567  C CA  . LEU A 115 ? 0.85091 0.57364 0.75454 0.07528  0.05098  0.11799  661 LEU A CA  
568  C C   . LEU A 115 ? 0.90020 0.58603 0.79173 0.06173  0.07442  0.12608  661 LEU A C   
569  O O   . LEU A 115 ? 0.93286 0.58331 0.80569 0.06990  0.07872  0.15138  661 LEU A O   
570  C CB  . LEU A 115 ? 0.89396 0.61019 0.82846 0.08197  0.05301  0.10655  661 LEU A CB  
571  C CG  . LEU A 115 ? 0.91141 0.65515 0.86221 0.09860  0.03504  0.10428  661 LEU A CG  
572  C CD1 . LEU A 115 ? 0.89685 0.62501 0.87227 0.10158  0.04741  0.08966  661 LEU A CD1 
573  C CD2 . LEU A 115 ? 0.91215 0.65806 0.85495 0.11733  0.01863  0.13316  661 LEU A CD2 
574  N N   . GLY A 116 ? 0.90322 0.59861 0.80830 0.04093  0.08915  0.10817  662 GLY A N   
575  C CA  . GLY A 116 ? 0.93859 0.60168 0.83880 0.02384  0.11398  0.11401  662 GLY A CA  
576  C C   . GLY A 116 ? 0.94702 0.63907 0.87784 -0.00041 0.12427  0.09184  662 GLY A C   
577  O O   . GLY A 116 ? 0.90980 0.64702 0.86258 -0.00131 0.11077  0.07565  662 GLY A O   
578  N N   . ALA A 117 ? 0.95071 0.61768 0.88586 -0.02075 0.14791  0.09423  663 ALA A N   
579  C CA  . ALA A 117 ? 0.88616 0.58728 0.85806 -0.04698 0.15741  0.07752  663 ALA A CA  
580  C C   . ALA A 117 ? 0.96439 0.62721 0.94397 -0.07289 0.18191  0.07732  663 ALA A C   
581  O O   . ALA A 117 ? 1.03531 0.64222 0.98596 -0.06849 0.19796  0.09589  663 ALA A O   
582  C CB  . ALA A 117 ? 0.80795 0.54390 0.78322 -0.04630 0.16552  0.08282  663 ALA A CB  
583  N N   . CYS A 118 ? 0.94580 0.64011 0.96542 -0.10144 0.18311  0.05776  664 CYS A N   
584  C CA  . CYS A 118 ? 1.03384 0.70313 1.06942 -0.13514 0.20649  0.05333  664 CYS A CA  
585  C C   . CYS A 118 ? 1.00416 0.72900 1.08159 -0.15445 0.21655  0.05380  664 CYS A C   
586  O O   . CYS A 118 ? 0.94687 0.73760 1.06495 -0.16074 0.19792  0.04187  664 CYS A O   
587  C CB  . CYS A 118 ? 1.01996 0.67970 1.06813 -0.15935 0.19837  0.02751  664 CYS A CB  
588  S SG  . CYS A 118 ? 0.98335 0.58734 0.99452 -0.13356 0.19046  0.02238  664 CYS A SG  
589  N N   . THR A 119 ? 1.05463 0.75434 1.12449 -0.16235 0.24722  0.07026  665 THR A N   
590  C CA  . THR A 119 ? 1.05696 0.80806 1.17087 -0.17770 0.26461  0.07299  665 THR A CA  
591  C C   . THR A 119 ? 1.13685 0.87184 1.27687 -0.21588 0.29477  0.07398  665 THR A C   
592  O O   . THR A 119 ? 1.14939 0.94485 1.35172 -0.23883 0.30113  0.06859  665 THR A O   
593  C CB  . THR A 119 ? 1.04521 0.79248 1.12682 -0.15193 0.28042  0.09134  665 THR A CB  
594  O OG1 . THR A 119 ? 1.09075 0.76410 1.10948 -0.14551 0.29885  0.11114  665 THR A OG1 
595  C CG2 . THR A 119 ? 1.01733 0.79065 1.08353 -0.11987 0.25182  0.08760  665 THR A CG2 
596  N N   . LYS A 120 ? 1.24416 0.90147 1.34420 -0.22353 0.31401  0.08264  666 LYS A N   
597  C CA  . LYS A 120 ? 1.35613 0.98991 1.47692 -0.26112 0.34761  0.08565  666 LYS A CA  
598  C C   . LYS A 120 ? 1.38567 1.01646 1.53792 -0.29960 0.33866  0.06051  666 LYS A C   
599  O O   . LYS A 120 ? 1.36673 0.97061 1.49659 -0.29338 0.31741  0.04565  666 LYS A O   
600  C CB  . LYS A 120 ? 1.45516 1.00058 1.51484 -0.25210 0.37760  0.11204  666 LYS A CB  
601  C CG  . LYS A 120 ? 1.52681 1.00658 1.53114 -0.22272 0.36241  0.12076  666 LYS A CG  
602  C CD  . LYS A 120 ? 1.63873 1.05156 1.58176 -0.20440 0.38478  0.15714  666 LYS A CD  
603  C CE  . LYS A 120 ? 1.62993 1.07783 1.54931 -0.18866 0.38927  0.17190  666 LYS A CE  
604  N NZ  . LYS A 120 ? 1.67629 1.06147 1.52175 -0.17090 0.40285  0.20848  666 LYS A NZ  
605  N N   . SER A 121 ? 1.45791 1.11864 1.66298 -0.34219 0.35672  0.05464  667 SER A N   
606  C CA  . SER A 121 ? 1.49317 1.14762 1.72606 -0.39106 0.35325  0.03002  667 SER A CA  
607  C C   . SER A 121 ? 1.40522 1.10455 1.64915 -0.39508 0.30899  0.00354  667 SER A C   
608  O O   . SER A 121 ? 1.41431 1.06961 1.63640 -0.41864 0.30239  -0.01932 667 SER A O   
609  C CB  . SER A 121 ? 1.62983 1.17213 1.81263 -0.40204 0.38113  0.03180  667 SER A CB  
610  O OG  . SER A 121 ? 1.69206 1.18410 1.82821 -0.37810 0.36295  0.02139  667 SER A OG  
611  N N   . GLY A 122 ? 1.27762 1.06091 1.55251 -0.37309 0.28128  0.00651  668 GLY A N   
612  C CA  . GLY A 122 ? 1.21638 1.04887 1.50184 -0.37790 0.23883  -0.01387 668 GLY A CA  
613  C C   . GLY A 122 ? 1.12536 1.03423 1.43522 -0.34151 0.21338  -0.00283 668 GLY A C   
614  O O   . GLY A 122 ? 1.10233 1.02275 1.41781 -0.31065 0.23021  0.01793  668 GLY A O   
615  N N   . PRO A 123 ? 1.09663 1.05269 1.41521 -0.34559 0.17420  -0.01701 669 PRO A N   
616  C CA  . PRO A 123 ? 1.03448 1.05922 1.37742 -0.31117 0.14991  -0.00519 669 PRO A CA  
617  C C   . PRO A 123 ? 0.99127 0.96705 1.27524 -0.26131 0.15295  0.00272  669 PRO A C   
618  O O   . PRO A 123 ? 1.01306 0.91489 1.23856 -0.25339 0.15873  -0.00460 669 PRO A O   
619  C CB  . PRO A 123 ? 1.04691 1.12089 1.40125 -0.33524 0.10732  -0.02212 669 PRO A CB  
620  C CG  . PRO A 123 ? 1.10657 1.10194 1.40220 -0.36257 0.11192  -0.04757 669 PRO A CG  
621  C CD  . PRO A 123 ? 1.14789 1.08595 1.44330 -0.38127 0.15282  -0.04490 669 PRO A CD  
622  N N   . ILE A 124 ? 0.91800 0.93706 1.22194 -0.22804 0.14957  0.01823  670 ILE A N   
623  C CA  . ILE A 124 ? 0.84600 0.82331 1.09743 -0.18523 0.15433  0.02694  670 ILE A CA  
624  C C   . ILE A 124 ? 0.79861 0.76150 1.01215 -0.17167 0.12470  0.01501  670 ILE A C   
625  O O   . ILE A 124 ? 0.81673 0.83122 1.05364 -0.17722 0.09607  0.00814  670 ILE A O   
626  C CB  . ILE A 124 ? 0.85287 0.87533 1.13419 -0.15838 0.16244  0.04239  670 ILE A CB  
627  C CG1 . ILE A 124 ? 0.96096 0.99058 1.27577 -0.17131 0.20031  0.05352  670 ILE A CG1 
628  C CG2 . ILE A 124 ? 0.82333 0.80392 1.04585 -0.12068 0.16341  0.04817  670 ILE A CG2 
629  C CD1 . ILE A 124 ? 0.97756 1.09404 1.38036 -0.17707 0.20161  0.06078  670 ILE A CD1 
630  N N   . TYR A 125 ? 0.77503 0.66911 0.93159 -0.15377 0.13221  0.01514  671 TYR A N   
631  C CA  . TYR A 125 ? 0.76067 0.63713 0.88216 -0.13393 0.11168  0.00729  671 TYR A CA  
632  C C   . TYR A 125 ? 0.75661 0.61882 0.85016 -0.09516 0.11336  0.02304  671 TYR A C   
633  O O   . TYR A 125 ? 0.80904 0.63186 0.87867 -0.08593 0.13357  0.03707  671 TYR A O   
634  C CB  . TYR A 125 ? 0.81199 0.62106 0.89812 -0.14493 0.12016  -0.00528 671 TYR A CB  
635  C CG  . TYR A 125 ? 0.84818 0.65757 0.94623 -0.18826 0.11803  -0.02775 671 TYR A CG  
636  C CD1 . TYR A 125 ? 0.83182 0.71207 0.96767 -0.21370 0.09545  -0.03604 671 TYR A CD1 
637  C CD2 . TYR A 125 ? 0.91901 0.65595 0.98963 -0.20501 0.13832  -0.03995 671 TYR A CD2 
638  C CE1 . TYR A 125 ? 0.91284 0.79533 1.05352 -0.25962 0.08931  -0.05775 671 TYR A CE1 
639  C CE2 . TYR A 125 ? 0.97588 0.70555 1.04930 -0.25025 0.13806  -0.06498 671 TYR A CE2 
640  C CZ  . TYR A 125 ? 0.97165 0.77598 1.07738 -0.27992 0.11157  -0.07482 671 TYR A CZ  
641  O OH  . TYR A 125 ? 1.03891 0.83835 1.14188 -0.33102 0.10725  -0.10082 671 TYR A OH  
642  N N   . ILE A 126 ? 0.73203 0.62454 0.82475 -0.07552 0.09161  0.02139  672 ILE A N   
643  C CA  . ILE A 126 ? 0.71897 0.59797 0.78261 -0.04366 0.08897  0.03233  672 ILE A CA  
644  C C   . ILE A 126 ? 0.74967 0.60577 0.78780 -0.03151 0.07399  0.02541  672 ILE A C   
645  O O   . ILE A 126 ? 0.73457 0.61703 0.78214 -0.03533 0.05666  0.01361  672 ILE A O   
646  C CB  . ILE A 126 ? 0.69120 0.61900 0.77769 -0.03041 0.08205  0.03684  672 ILE A CB  
647  C CG1 . ILE A 126 ? 0.76147 0.71339 0.88243 -0.04090 0.10347  0.04373  672 ILE A CG1 
648  C CG2 . ILE A 126 ? 0.67674 0.58496 0.72715 -0.00418 0.08029  0.04455  672 ILE A CG2 
649  C CD1 . ILE A 126 ? 0.78263 0.77562 0.93155 -0.02481 0.10493  0.04919  672 ILE A CD1 
650  N N   . ILE A 127 ? 0.74857 0.55741 0.75607 -0.01673 0.08148  0.03513  673 ILE A N   
651  C CA  . ILE A 127 ? 0.75559 0.53899 0.74824 -0.00387 0.07445  0.03115  673 ILE A CA  
652  C C   . ILE A 127 ? 0.75147 0.54987 0.73272 0.02230  0.05921  0.04128  673 ILE A C   
653  O O   . ILE A 127 ? 0.74338 0.53457 0.70724 0.03344  0.06047  0.05775  673 ILE A O   
654  C CB  . ILE A 127 ? 0.78323 0.50664 0.76099 -0.00264 0.09304  0.03943  673 ILE A CB  
655  C CG1 . ILE A 127 ? 0.79223 0.49592 0.77989 -0.03401 0.11089  0.02760  673 ILE A CG1 
656  C CG2 . ILE A 127 ? 0.77687 0.47577 0.75015 0.01345  0.09121  0.03556  673 ILE A CG2 
657  C CD1 . ILE A 127 ? 0.86670 0.50541 0.84006 -0.03399 0.13478  0.04040  673 ILE A CD1 
658  N N   . ILE A 128 ? 0.71024 0.52794 0.69715 0.02866  0.04535  0.03092  674 ILE A N   
659  C CA  . ILE A 128 ? 0.75294 0.58768 0.73412 0.04898  0.03077  0.03795  674 ILE A CA  
660  C C   . ILE A 128 ? 0.74184 0.56428 0.72511 0.05931  0.02871  0.03318  674 ILE A C   
661  O O   . ILE A 128 ? 0.70845 0.51948 0.69464 0.04794  0.03622  0.01739  674 ILE A O   
662  C CB  . ILE A 128 ? 0.81336 0.69138 0.80557 0.04695  0.01928  0.03227  674 ILE A CB  
663  C CG1 . ILE A 128 ? 0.86792 0.75153 0.85175 0.05153  0.02299  0.04263  674 ILE A CG1 
664  C CG2 . ILE A 128 ? 0.78144 0.67585 0.77460 0.05794  0.00556  0.02828  674 ILE A CG2 
665  C CD1 . ILE A 128 ? 0.92479 0.82623 0.92833 0.03829  0.03439  0.04053  674 ILE A CD1 
666  N N   . GLU A 129 ? 0.78497 0.60943 0.76649 0.07898  0.02009  0.04649  675 GLU A N   
667  C CA  . GLU A 129 ? 0.83281 0.65111 0.82646 0.09207  0.02147  0.04503  675 GLU A CA  
668  C C   . GLU A 129 ? 0.77962 0.62186 0.77725 0.08498  0.01758  0.02627  675 GLU A C   
669  O O   . GLU A 129 ? 0.75320 0.62666 0.74905 0.08111  0.00461  0.02429  675 GLU A O   
670  C CB  . GLU A 129 ? 0.90427 0.73346 0.90355 0.11190  0.00825  0.06612  675 GLU A CB  
671  C CG  . GLU A 129 ? 0.94769 0.77120 0.97271 0.12936  0.01411  0.07105  675 GLU A CG  
672  C CD  . GLU A 129 ? 0.97014 0.80950 1.00913 0.14758  -0.00222 0.09810  675 GLU A CD  
673  O OE1 . GLU A 129 ? 0.93025 0.79210 0.95202 0.14263  -0.02227 0.10584  675 GLU A OE1 
674  O OE2 . GLU A 129 ? 0.97887 0.80818 1.04705 0.16606  0.00550  0.11203  675 GLU A OE2 
675  N N   . TYR A 130 ? 0.76473 0.58736 0.76474 0.08335  0.03166  0.01324  676 TYR A N   
676  C CA  . TYR A 130 ? 0.73555 0.57447 0.72825 0.07271  0.03040  -0.00471 676 TYR A CA  
677  C C   . TYR A 130 ? 0.66835 0.53438 0.67253 0.08795  0.02138  0.00240  676 TYR A C   
678  O O   . TYR A 130 ? 0.69089 0.55264 0.71445 0.10647  0.02605  0.01350  676 TYR A O   
679  C CB  . TYR A 130 ? 0.77429 0.57574 0.75625 0.06331  0.05339  -0.02397 676 TYR A CB  
680  C CG  . TYR A 130 ? 0.85312 0.66650 0.81351 0.04652  0.05272  -0.04359 676 TYR A CG  
681  C CD1 . TYR A 130 ? 0.87049 0.70261 0.81186 0.02008  0.03881  -0.05367 676 TYR A CD1 
682  C CD2 . TYR A 130 ? 0.89659 0.70532 0.85654 0.05637  0.06586  -0.04948 676 TYR A CD2 
683  C CE1 . TYR A 130 ? 0.85938 0.70345 0.77416 0.00294  0.03434  -0.06760 676 TYR A CE1 
684  C CE2 . TYR A 130 ? 0.89462 0.71046 0.82503 0.03893  0.06671  -0.06608 676 TYR A CE2 
685  C CZ  . TYR A 130 ? 0.88454 0.71719 0.78853 0.01176  0.04904  -0.07433 676 TYR A CZ  
686  O OH  . TYR A 130 ? 0.93094 0.77193 0.79914 -0.00707 0.04607  -0.08686 676 TYR A OH  
687  N N   . CYS A 131 ? 0.66516 0.56076 0.66176 0.07972  0.00847  -0.00172 677 CYS A N   
688  C CA  . CYS A 131 ? 0.63846 0.55756 0.64343 0.08890  0.00166  0.00325  677 CYS A CA  
689  C C   . CYS A 131 ? 0.68284 0.59697 0.67615 0.08207  0.01433  -0.01117 677 CYS A C   
690  O O   . CYS A 131 ? 0.70488 0.62187 0.67417 0.06422  0.01148  -0.02197 677 CYS A O   
691  C CB  . CYS A 131 ? 0.60423 0.54998 0.60647 0.08538  -0.01549 0.00965  677 CYS A CB  
692  S SG  . CYS A 131 ? 0.68295 0.62752 0.68779 0.09060  -0.02349 0.02264  677 CYS A SG  
693  N N   . PHE A 132 ? 0.66550 0.57475 0.67632 0.09548  0.02828  -0.00969 678 PHE A N   
694  C CA  . PHE A 132 ? 0.71536 0.60714 0.71317 0.09034  0.05158  -0.02587 678 PHE A CA  
695  C C   . PHE A 132 ? 0.75776 0.66561 0.72494 0.07389  0.04517  -0.03321 678 PHE A C   
696  O O   . PHE A 132 ? 0.72462 0.61434 0.65533 0.05598  0.05626  -0.05058 678 PHE A O   
697  C CB  . PHE A 132 ? 0.72035 0.61467 0.75683 0.11170  0.06825  -0.01763 678 PHE A CB  
698  C CG  . PHE A 132 ? 0.78164 0.65518 0.80914 0.10958  0.10080  -0.03443 678 PHE A CG  
699  C CD1 . PHE A 132 ? 0.80454 0.63356 0.82773 0.11158  0.13112  -0.04841 678 PHE A CD1 
700  C CD2 . PHE A 132 ? 0.75981 0.65294 0.78175 0.10529  0.10571  -0.03650 678 PHE A CD2 
701  C CE1 . PHE A 132 ? 0.91633 0.71953 0.92648 0.10886  0.16767  -0.06707 678 PHE A CE1 
702  C CE2 . PHE A 132 ? 0.85829 0.72938 0.86663 0.10210  0.14068  -0.05283 678 PHE A CE2 
703  C CZ  . PHE A 132 ? 0.89002 0.71545 0.89126 0.10388  0.17280  -0.06949 678 PHE A CZ  
704  N N   . TYR A 133 ? 0.68452 0.62296 0.66165 0.07779  0.02747  -0.01958 679 TYR A N   
705  C CA  . TYR A 133 ? 0.67293 0.62443 0.62559 0.06661  0.02400  -0.02034 679 TYR A CA  
706  C C   . TYR A 133 ? 0.71118 0.67512 0.64007 0.05184  0.00280  -0.01739 679 TYR A C   
707  O O   . TYR A 133 ? 0.80553 0.78035 0.71105 0.04229  -0.00313 -0.01360 679 TYR A O   
708  C CB  . TYR A 133 ? 0.62587 0.59938 0.60346 0.07708  0.01926  -0.00628 679 TYR A CB  
709  C CG  . TYR A 133 ? 0.63861 0.61237 0.64654 0.08888  0.03939  -0.00639 679 TYR A CG  
710  C CD1 . TYR A 133 ? 0.65418 0.61713 0.64875 0.08444  0.06536  -0.01670 679 TYR A CD1 
711  C CD2 . TYR A 133 ? 0.59814 0.58561 0.64896 0.10353  0.03275  0.00527  679 TYR A CD2 
712  C CE1 . TYR A 133 ? 0.68964 0.65760 0.72318 0.09732  0.08783  -0.01508 679 TYR A CE1 
713  C CE2 . TYR A 133 ? 0.68101 0.67882 0.77181 0.11535  0.04857  0.00967  679 TYR A CE2 
714  C CZ  . TYR A 133 ? 0.73783 0.72697 0.82509 0.11373  0.07788  -0.00037 679 TYR A CZ  
715  O OH  . TYR A 133 ? 0.83156 0.83531 0.96944 0.12761  0.09763  0.00556  679 TYR A OH  
716  N N   . GLY A 134 ? 0.66781 0.63266 0.60521 0.05006  -0.00812 -0.01613 680 GLY A N   
717  C CA  . GLY A 134 ? 0.67855 0.66407 0.60843 0.03834  -0.02774 -0.00980 680 GLY A CA  
718  C C   . GLY A 134 ? 0.63702 0.64553 0.58613 0.04982  -0.04072 0.00899  680 GLY A C   
719  O O   . GLY A 134 ? 0.62459 0.63051 0.59205 0.06400  -0.03694 0.01469  680 GLY A O   
720  N N   . ASP A 135 ? 0.64781 0.67869 0.59318 0.04227  -0.05630 0.01942  681 ASP A N   
721  C CA  . ASP A 135 ? 0.70264 0.75006 0.67062 0.05476  -0.06465 0.03832  681 ASP A CA  
722  C C   . ASP A 135 ? 0.69488 0.73764 0.65372 0.06050  -0.06034 0.04629  681 ASP A C   
723  O O   . ASP A 135 ? 0.63177 0.66875 0.56279 0.05152  -0.05537 0.04155  681 ASP A O   
724  C CB  . ASP A 135 ? 0.71192 0.78944 0.69048 0.04833  -0.08225 0.05241  681 ASP A CB  
725  C CG  . ASP A 135 ? 0.82048 0.91221 0.76940 0.03472  -0.09524 0.06034  681 ASP A CG  
726  O OD1 . ASP A 135 ? 0.83310 0.93115 0.78320 0.04363  -0.09922 0.07926  681 ASP A OD1 
727  O OD2 . ASP A 135 ? 0.91611 1.00873 0.83580 0.01321  -0.10051 0.04767  681 ASP A OD2 
728  N N   . LEU A 136 ? 0.65603 0.69733 0.63609 0.07356  -0.05895 0.05736  682 LEU A N   
729  C CA  . LEU A 136 ? 0.63255 0.66392 0.60874 0.07727  -0.05152 0.06315  682 LEU A CA  
730  C C   . LEU A 136 ? 0.58283 0.62216 0.54071 0.07280  -0.05736 0.07962  682 LEU A C   
731  O O   . LEU A 136 ? 0.67548 0.70561 0.61623 0.06863  -0.04831 0.08070  682 LEU A O   
732  C CB  . LEU A 136 ? 0.65328 0.67371 0.65131 0.08771  -0.04697 0.06745  682 LEU A CB  
733  C CG  . LEU A 136 ? 0.71024 0.71652 0.70845 0.08710  -0.03783 0.06867  682 LEU A CG  
734  C CD1 . LEU A 136 ? 0.70259 0.71036 0.69848 0.08119  -0.03194 0.05617  682 LEU A CD1 
735  C CD2 . LEU A 136 ? 0.70760 0.69707 0.71895 0.09167  -0.03308 0.06754  682 LEU A CD2 
736  N N   . VAL A 137 ? 0.53487 0.59387 0.49801 0.07318  -0.07252 0.09524  683 VAL A N   
737  C CA  . VAL A 137 ? 0.63734 0.70742 0.58164 0.06933  -0.08303 0.11747  683 VAL A CA  
738  C C   . VAL A 137 ? 0.71596 0.78232 0.61094 0.04998  -0.08189 0.10693  683 VAL A C   
739  O O   . VAL A 137 ? 0.71484 0.76960 0.58363 0.04636  -0.07393 0.11473  683 VAL A O   
740  C CB  . VAL A 137 ? 0.69064 0.79326 0.65717 0.07238  -0.10414 0.13872  683 VAL A CB  
741  C CG1 . VAL A 137 ? 0.74459 0.86267 0.68951 0.06818  -0.12018 0.16747  683 VAL A CG1 
742  C CG2 . VAL A 137 ? 0.71890 0.81986 0.73496 0.09343  -0.09681 0.14849  683 VAL A CG2 
743  N N   . ASN A 138 ? 0.71986 0.79094 0.59888 0.03573  -0.08577 0.08770  684 ASN A N   
744  C CA  . ASN A 138 ? 0.76643 0.82593 0.59223 0.01491  -0.07930 0.07268  684 ASN A CA  
745  C C   . ASN A 138 ? 0.72989 0.76168 0.54990 0.01921  -0.05010 0.05691  684 ASN A C   
746  O O   . ASN A 138 ? 0.75434 0.77337 0.53301 0.00757  -0.03707 0.05328  684 ASN A O   
747  C CB  . ASN A 138 ? 0.77844 0.84053 0.59072 -0.00274 -0.08540 0.05200  684 ASN A CB  
748  C CG  . ASN A 138 ? 0.86866 0.96554 0.67408 -0.01792 -0.11676 0.06767  684 ASN A CG  
749  O OD1 . ASN A 138 ? 0.98986 1.10120 0.76300 -0.02818 -0.13256 0.08644  684 ASN A OD1 
750  N ND2 . ASN A 138 ? 0.87734 0.99103 0.71546 -0.02016 -0.12685 0.06292  684 ASN A ND2 
751  N N   . TYR A 139 ? 0.62590 0.65076 0.48759 0.03481  -0.03943 0.04906  685 TYR A N   
752  C CA  . TYR A 139 ? 0.64350 0.65325 0.51431 0.04006  -0.01548 0.03919  685 TYR A CA  
753  C C   . TYR A 139 ? 0.69095 0.69932 0.55739 0.04111  -0.00903 0.05545  685 TYR A C   
754  O O   . TYR A 139 ? 0.75451 0.75325 0.60369 0.03476  0.01167  0.05033  685 TYR A O   
755  C CB  . TYR A 139 ? 0.55581 0.56552 0.47199 0.05450  -0.01342 0.03341  685 TYR A CB  
756  C CG  . TYR A 139 ? 0.62731 0.63277 0.56541 0.06002  0.00611  0.02733  685 TYR A CG  
757  C CD1 . TYR A 139 ? 0.68142 0.67760 0.62063 0.06025  0.02511  0.01208  685 TYR A CD1 
758  C CD2 . TYR A 139 ? 0.67065 0.68190 0.63310 0.06430  0.00699  0.03738  685 TYR A CD2 
759  C CE1 . TYR A 139 ? 0.73113 0.73187 0.70337 0.06779  0.04307  0.01062  685 TYR A CE1 
760  C CE2 . TYR A 139 ? 0.72558 0.74267 0.71678 0.06673  0.02191  0.03390  685 TYR A CE2 
761  C CZ  . TYR A 139 ? 0.78254 0.79837 0.78266 0.07006  0.03916  0.02234  685 TYR A CZ  
762  O OH  . TYR A 139 ? 0.95621 0.98589 0.99757 0.07503  0.05416  0.02285  685 TYR A OH  
763  N N   . LEU A 140 ? 0.65421 0.66866 0.53791 0.04920  -0.02241 0.07528  686 LEU A N   
764  C CA  . LEU A 140 ? 0.67284 0.67929 0.55251 0.04955  -0.01495 0.09293  686 LEU A CA  
765  C C   . LEU A 140 ? 0.74015 0.74451 0.56813 0.03626  -0.01451 0.10468  686 LEU A C   
766  O O   . LEU A 140 ? 0.80304 0.79516 0.61354 0.02985  0.00425  0.10862  686 LEU A O   
767  C CB  . LEU A 140 ? 0.68958 0.69498 0.59673 0.06201  -0.02603 0.11164  686 LEU A CB  
768  C CG  . LEU A 140 ? 0.66058 0.65988 0.60678 0.07074  -0.02260 0.10016  686 LEU A CG  
769  C CD1 . LEU A 140 ? 0.65729 0.64849 0.62371 0.08243  -0.02796 0.11533  686 LEU A CD1 
770  C CD2 . LEU A 140 ? 0.65506 0.64512 0.61310 0.06508  -0.00605 0.09181  686 LEU A CD2 
771  N N   . HIS A 141 ? 0.68480 0.70263 0.48598 0.02921  -0.03547 0.11109  687 HIS A N   
772  C CA  . HIS A 141 ? 0.77741 0.79477 0.51783 0.01166  -0.03998 0.12234  687 HIS A CA  
773  C C   . HIS A 141 ? 0.80395 0.80169 0.50297 -0.00430 -0.01238 0.09708  687 HIS A C   
774  O O   . HIS A 141 ? 0.81512 0.79931 0.47176 -0.01499 0.00274  0.10504  687 HIS A O   
775  C CB  . HIS A 141 ? 0.78068 0.82303 0.50325 0.00203  -0.07169 0.13023  687 HIS A CB  
776  C CG  . HIS A 141 ? 0.83449 0.90034 0.59725 0.01835  -0.09638 0.16254  687 HIS A CG  
777  N ND1 . HIS A 141 ? 0.86241 0.96189 0.63593 0.01440  -0.12607 0.17277  687 HIS A ND1 
778  C CD2 . HIS A 141 ? 0.83679 0.89616 0.63567 0.03865  -0.09264 0.18691  687 HIS A CD2 
779  C CE1 . HIS A 141 ? 0.83446 0.95025 0.65456 0.03515  -0.13823 0.20392  687 HIS A CE1 
780  N NE2 . HIS A 141 ? 0.81519 0.90243 0.64833 0.05037  -0.11691 0.21188  687 HIS A NE2 
781  N N   . LYS A 142 ? 0.77522 0.76803 0.48645 -0.00524 -0.00184 0.06765  688 LYS A N   
782  C CA  . LYS A 142 ? 0.84661 0.81693 0.52645 -0.01682 0.03031  0.04200  688 LYS A CA  
783  C C   . LYS A 142 ? 0.81911 0.78062 0.52394 -0.00844 0.06193  0.04256  688 LYS A C   
784  O O   . LYS A 142 ? 0.83581 0.77929 0.50643 -0.01947 0.09290  0.03022  688 LYS A O   
785  C CB  . LYS A 142 ? 0.90520 0.86907 0.60600 -0.01419 0.03615  0.01483  688 LYS A CB  
786  C CG  . LYS A 142 ? 1.00287 0.93775 0.67933 -0.02223 0.07468  -0.01324 688 LYS A CG  
787  C CD  . LYS A 142 ? 1.02133 0.94459 0.72016 -0.01795 0.07944  -0.03561 688 LYS A CD  
788  C CE  . LYS A 142 ? 1.10527 0.99613 0.79814 -0.01773 0.12455  -0.06107 688 LYS A CE  
789  N NZ  . LYS A 142 ? 1.10528 0.98013 0.82661 -0.00972 0.13077  -0.07818 688 LYS A NZ  
790  N N   . ASN A 143 ? 0.78739 0.76076 0.55005 0.00809  0.05676  0.05549  689 ASN A N   
791  C CA  . ASN A 143 ? 0.80745 0.77964 0.60417 0.01264  0.08292  0.05631  689 ASN A CA  
792  C C   . ASN A 143 ? 0.84989 0.81834 0.63904 0.00937  0.08191  0.08210  689 ASN A C   
793  O O   . ASN A 143 ? 0.84917 0.81827 0.67113 0.00986  0.10133  0.08469  689 ASN A O   
794  C CB  . ASN A 143 ? 0.74012 0.72693 0.60714 0.02831  0.07921  0.04906  689 ASN A CB  
795  C CG  . ASN A 143 ? 0.72772 0.71410 0.61029 0.03402  0.08978  0.02707  689 ASN A CG  
796  O OD1 . ASN A 143 ? 0.79374 0.77818 0.69218 0.03531  0.11968  0.01640  689 ASN A OD1 
797  N ND2 . ASN A 143 ? 0.67882 0.66603 0.56230 0.03869  0.06832  0.02188  689 ASN A ND2 
798  N N   . ARG A 144 ? 0.84641 0.81208 0.59751 0.00574  0.05965  0.10345  690 ARG A N   
799  C CA  . ARG A 144 ? 0.85799 0.81420 0.60494 0.00588  0.05942  0.13239  690 ARG A CA  
800  C C   . ARG A 144 ? 0.92759 0.86771 0.63825 -0.00895 0.09118  0.13647  690 ARG A C   
801  O O   . ARG A 144 ? 0.93350 0.86442 0.66710 -0.00944 0.10705  0.14881  690 ARG A O   
802  C CB  . ARG A 144 ? 0.90068 0.86111 0.61881 0.00812  0.02841  0.15976  690 ARG A CB  
803  C CG  . ARG A 144 ? 0.97059 0.91563 0.68736 0.01219  0.02937  0.19444  690 ARG A CG  
804  C CD  . ARG A 144 ? 1.00313 0.95797 0.70712 0.02027  -0.00254 0.22776  690 ARG A CD  
805  N NE  . ARG A 144 ? 1.11551 1.04958 0.83920 0.03179  0.00199  0.26036  690 ARG A NE  
806  C CZ  . ARG A 144 ? 1.23214 1.16752 0.94265 0.04007  -0.01746 0.30117  690 ARG A CZ  
807  N NH1 . ARG A 144 ? 1.26487 1.22919 0.94175 0.03507  -0.04768 0.31491  690 ARG A NH1 
808  N NH2 . ARG A 144 ? 1.26243 1.17012 0.99509 0.05236  -0.00698 0.32969  690 ARG A NH2 
809  N N   . ASP A 145 ? 0.98632 0.91942 0.63752 -0.02384 0.10395  0.12473  691 ASP A N   
810  C CA  . ASP A 145 ? 1.04482 0.95854 0.64744 -0.04009 0.13595  0.13167  691 ASP A CA  
811  C C   . ASP A 145 ? 0.98227 0.89662 0.63248 -0.03938 0.17732  0.11371  691 ASP A C   
812  O O   . ASP A 145 ? 0.94372 0.84672 0.58589 -0.04860 0.20469  0.12604  691 ASP A O   
813  C CB  . ASP A 145 ? 1.11769 1.01876 0.63115 -0.06023 0.13916  0.12214  691 ASP A CB  
814  C CG  . ASP A 145 ? 1.15919 1.06594 0.62041 -0.06661 0.09729  0.14975  691 ASP A CG  
815  O OD1 . ASP A 145 ? 1.12960 1.04604 0.62625 -0.05195 0.07291  0.17986  691 ASP A OD1 
816  O OD2 . ASP A 145 ? 1.22367 1.12552 0.61066 -0.08688 0.08916  0.14170  691 ASP A OD2 
817  N N   . SER A 146 ? 0.99109 0.92074 0.69435 -0.02869 0.18271  0.08780  692 SER A N   
818  C CA  . SER A 146 ? 1.09762 1.03879 0.86115 -0.02518 0.21772  0.07463  692 SER A CA  
819  C C   . SER A 146 ? 1.09301 1.05615 0.93700 -0.01560 0.20390  0.08349  692 SER A C   
820  O O   . SER A 146 ? 1.06353 1.04876 0.97284 -0.01125 0.22153  0.07355  692 SER A O   
821  C CB  . SER A 146 ? 1.10359 1.04894 0.88443 -0.01749 0.23326  0.04573  692 SER A CB  
822  O OG  . SER A 146 ? 1.09981 1.05298 0.89502 -0.00601 0.19770  0.03935  692 SER A OG  
823  N N   . PHE A 147 ? 1.11312 1.07060 0.95434 -0.01332 0.17377  0.10225  693 PHE A N   
824  C CA  . PHE A 147 ? 1.13844 1.10840 1.04428 -0.00851 0.16094  0.10596  693 PHE A CA  
825  C C   . PHE A 147 ? 1.21946 1.19280 1.15858 -0.02176 0.18959  0.11212  693 PHE A C   
826  O O   . PHE A 147 ? 1.25812 1.21023 1.15906 -0.03368 0.20921  0.12800  693 PHE A O   
827  C CB  . PHE A 147 ? 1.12520 1.07850 1.01555 -0.00322 0.13139  0.12402  693 PHE A CB  
828  C CG  . PHE A 147 ? 1.02907 0.98673 0.97384 -0.00013 0.11825  0.12153  693 PHE A CG  
829  C CD1 . PHE A 147 ? 0.99644 0.96977 0.96906 0.01068  0.09663  0.10672  693 PHE A CD1 
830  C CD2 . PHE A 147 ? 1.03998 0.98155 1.00195 -0.01125 0.12910  0.13312  693 PHE A CD2 
831  C CE1 . PHE A 147 ? 0.98977 0.96342 1.00009 0.00937  0.08502  0.10256  693 PHE A CE1 
832  C CE2 . PHE A 147 ? 1.02108 0.96113 1.02362 -0.01392 0.11797  0.12660  693 PHE A CE2 
833  C CZ  . PHE A 147 ? 0.98490 0.94131 1.00838 -0.00414 0.09544  0.11086  693 PHE A CZ  
834  N N   . LEU A 148 ? 1.22921 1.23143 1.24006 -0.02152 0.19069  0.10155  694 LEU A N   
835  C CA  . LEU A 148 ? 1.27536 1.29041 1.33200 -0.03741 0.21478  0.10635  694 LEU A CA  
836  C C   . LEU A 148 ? 1.32129 1.31434 1.38066 -0.04909 0.20219  0.11995  694 LEU A C   
837  O O   . LEU A 148 ? 1.28392 1.28619 1.38016 -0.04992 0.17882  0.11353  694 LEU A O   
838  C CB  . LEU A 148 ? 1.20234 1.26493 1.34091 -0.03453 0.21608  0.09306  694 LEU A CB  
839  N N   . GLY A 171 ? 1.21740 1.30179 1.38246 0.05737  0.22199  0.02666  789 GLY A N   
840  C CA  . GLY A 171 ? 1.25069 1.31246 1.35132 0.04182  0.20158  0.03277  789 GLY A CA  
841  C C   . GLY A 171 ? 1.23914 1.30791 1.34783 0.04367  0.15689  0.04045  789 GLY A C   
842  O O   . GLY A 171 ? 1.27577 1.36155 1.42297 0.05545  0.13835  0.03878  789 GLY A O   
843  N N   . LEU A 172 ? 1.09587 1.14798 1.16575 0.03250  0.14241  0.05017  790 LEU A N   
844  C CA  . LEU A 172 ? 0.94872 1.00002 1.02325 0.03274  0.10848  0.05671  790 LEU A CA  
845  C C   . LEU A 172 ? 0.88626 0.94113 0.98304 0.01850  0.11128  0.06722  790 LEU A C   
846  O O   . LEU A 172 ? 0.92287 0.96331 0.99616 0.00797  0.13162  0.07559  790 LEU A O   
847  C CB  . LEU A 172 ? 0.96359 0.98844 0.97911 0.03435  0.09105  0.06052  790 LEU A CB  
848  C CG  . LEU A 172 ? 0.87762 0.90139 0.88884 0.04514  0.06495  0.05484  790 LEU A CG  
849  C CD1 . LEU A 172 ? 0.83841 0.84556 0.81620 0.04485  0.04659  0.06670  790 LEU A CD1 
850  C CD2 . LEU A 172 ? 0.84487 0.88672 0.90467 0.05059  0.05107  0.05100  790 LEU A CD2 
851  N N   . THR A 173 ? 0.78738 0.85820 0.92432 0.01521  0.09170  0.06660  791 THR A N   
852  C CA  . THR A 173 ? 0.78587 0.85890 0.94712 -0.00352 0.09394  0.07245  791 THR A CA  
853  C C   . THR A 173 ? 0.74285 0.78866 0.88277 -0.00795 0.07161  0.07299  791 THR A C   
854  O O   . THR A 173 ? 0.74686 0.78354 0.86717 0.00441  0.05267  0.06862  791 THR A O   
855  C CB  . THR A 173 ? 0.84032 0.95992 1.07258 -0.01112 0.09267  0.06985  791 THR A CB  
856  O OG1 . THR A 173 ? 0.87628 1.01009 1.12405 -0.00718 0.06097  0.06487  791 THR A OG1 
857  C CG2 . THR A 173 ? 0.81025 0.95741 1.07367 0.00092  0.11733  0.06877  791 THR A CG2 
858  N N   . LEU A 174 ? 0.72738 0.74272 0.74755 0.02289  0.16369  0.07060  792 LEU A N   
859  C CA  . LEU A 174 ? 0.72296 0.71549 0.75017 0.00979  0.14299  0.07423  792 LEU A CA  
860  C C   . LEU A 174 ? 0.66864 0.65498 0.71340 0.00548  0.11087  0.05274  792 LEU A C   
861  O O   . LEU A 174 ? 0.69307 0.65821 0.71406 0.00124  0.09029  0.04615  792 LEU A O   
862  C CB  . LEU A 174 ? 0.84034 0.83862 0.92286 -0.00385 0.15949  0.09462  792 LEU A CB  
863  C CG  . LEU A 174 ? 0.93017 0.90619 1.04011 -0.01881 0.13958  0.09072  792 LEU A CG  
864  C CD1 . LEU A 174 ? 0.97212 0.92120 1.03370 -0.01586 0.13596  0.10012  792 LEU A CD1 
865  C CD2 . LEU A 174 ? 0.95991 0.94462 1.14765 -0.03400 0.15395  0.10414  792 LEU A CD2 
866  N N   . LEU A 175 ? 0.65682 0.66459 0.74375 0.00756  0.10703  0.04355  793 LEU A N   
867  C CA  . LEU A 175 ? 0.63996 0.64760 0.74105 0.00500  0.07469  0.02856  793 LEU A CA  
868  C C   . LEU A 175 ? 0.63498 0.62427 0.68210 0.01503  0.05884  0.02045  793 LEU A C   
869  O O   . LEU A 175 ? 0.65506 0.63316 0.68648 0.01049  0.03438  0.01469  793 LEU A O   
870  C CB  . LEU A 175 ? 0.61770 0.65582 0.78085 0.00790  0.07358  0.02524  793 LEU A CB  
871  C CG  . LEU A 175 ? 0.64601 0.70647 0.87958 -0.00489 0.08574  0.03258  793 LEU A CG  
872  C CD1 . LEU A 175 ? 0.67404 0.76877 0.97806 -0.00172 0.07988  0.02875  793 LEU A CD1 
873  C CD2 . LEU A 175 ? 0.57896 0.62624 0.82266 -0.02293 0.06577  0.02761  793 LEU A CD2 
874  N N   . ASP A 176 ? 0.59920 0.58662 0.61910 0.02830  0.07342  0.01875  794 ASP A N   
875  C CA  . ASP A 176 ? 0.68218 0.65045 0.65995 0.03610  0.05936  0.01068  794 ASP A CA  
876  C C   . ASP A 176 ? 0.66210 0.60819 0.59811 0.02920  0.05043  0.01462  794 ASP A C   
877  O O   . ASP A 176 ? 0.63836 0.57123 0.55702 0.02857  0.03141  0.01105  794 ASP A O   
878  C CB  . ASP A 176 ? 0.77881 0.74885 0.73633 0.04993  0.07728  0.00220  794 ASP A CB  
879  C CG  . ASP A 176 ? 0.85279 0.84215 0.85606 0.06023  0.08608  -0.00654 794 ASP A CG  
880  O OD1 . ASP A 176 ? 0.86321 0.85417 0.90092 0.06169  0.06628  -0.00775 794 ASP A OD1 
881  O OD2 . ASP A 176 ? 0.93708 0.94210 0.94241 0.06799  0.11373  -0.01084 794 ASP A OD2 
882  N N   . LEU A 177 ? 0.65918 0.60237 0.58330 0.02474  0.06569  0.02493  795 LEU A N   
883  C CA  . LEU A 177 ? 0.65813 0.58152 0.55410 0.01957  0.05853  0.02985  795 LEU A CA  
884  C C   . LEU A 177 ? 0.62176 0.53883 0.53635 0.00873  0.04214  0.02429  795 LEU A C   
885  O O   . LEU A 177 ? 0.66771 0.57048 0.55890 0.00756  0.03000  0.01996  795 LEU A O   
886  C CB  . LEU A 177 ? 0.68815 0.61125 0.57774 0.01816  0.07808  0.04756  795 LEU A CB  
887  C CG  . LEU A 177 ? 0.74814 0.68392 0.60946 0.02877  0.09706  0.05464  795 LEU A CG  
888  C CD1 . LEU A 177 ? 0.82018 0.75390 0.66399 0.02806  0.11047  0.07954  795 LEU A CD1 
889  C CD2 . LEU A 177 ? 0.73557 0.66693 0.55911 0.03903  0.08559  0.03756  795 LEU A CD2 
890  N N   . LEU A 178 ? 0.60676 0.53704 0.56470 0.00055  0.04199  0.02235  796 LEU A N   
891  C CA  . LEU A 178 ? 0.64374 0.57261 0.61631 -0.00987 0.02302  0.01030  796 LEU A CA  
892  C C   . LEU A 178 ? 0.64299 0.57521 0.59377 -0.00537 0.00131  0.00268  796 LEU A C   
893  O O   . LEU A 178 ? 0.59962 0.52433 0.52868 -0.00961 -0.01185 -0.00530 796 LEU A O   
894  C CB  . LEU A 178 ? 0.63626 0.58340 0.66670 -0.02000 0.02319  0.00722  796 LEU A CB  
895  C CG  . LEU A 178 ? 0.67893 0.61900 0.74205 -0.02908 0.04249  0.01638  796 LEU A CG  
896  C CD1 . LEU A 178 ? 0.65406 0.61516 0.78671 -0.04033 0.04309  0.01377  796 LEU A CD1 
897  C CD2 . LEU A 178 ? 0.72131 0.63679 0.77157 -0.03568 0.03654  0.00770  796 LEU A CD2 
898  N N   . SER A 179 ? 0.61251 0.55622 0.57039 0.00413  -0.00050 0.00637  797 SER A N   
899  C CA  . SER A 179 ? 0.58328 0.52923 0.52808 0.00940  -0.02025 0.00657  797 SER A CA  
900  C C   . SER A 179 ? 0.64420 0.56922 0.54481 0.01282  -0.02062 0.00908  797 SER A C   
901  O O   . SER A 179 ? 0.66021 0.58337 0.54048 0.01057  -0.03429 0.01012  797 SER A O   
902  C CB  . SER A 179 ? 0.55034 0.50925 0.52447 0.02050  -0.01930 0.01051  797 SER A CB  
903  O OG  . SER A 179 ? 0.65905 0.61683 0.62673 0.02667  -0.03745 0.01672  797 SER A OG  
904  N N   . PHE A 180 ? 0.65621 0.56878 0.54190 0.01821  -0.00568 0.01061  798 PHE A N   
905  C CA  . PHE A 180 ? 0.67474 0.57011 0.52846 0.02001  -0.00691 0.01232  798 PHE A CA  
906  C C   . PHE A 180 ? 0.67938 0.56805 0.51819 0.01176  -0.00904 0.01056  798 PHE A C   
907  O O   . PHE A 180 ? 0.66030 0.54365 0.48076 0.01128  -0.01536 0.01213  798 PHE A O   
908  C CB  . PHE A 180 ? 0.65361 0.54178 0.49383 0.02550  0.00605  0.01205  798 PHE A CB  
909  C CG  . PHE A 180 ? 0.67383 0.56824 0.52342 0.03490  0.01147  0.00642  798 PHE A CG  
910  C CD1 . PHE A 180 ? 0.65434 0.55348 0.52847 0.03982  0.00320  0.00410  798 PHE A CD1 
911  C CD2 . PHE A 180 ? 0.69491 0.59170 0.52855 0.04005  0.02532  0.00338  798 PHE A CD2 
912  C CE1 . PHE A 180 ? 0.62146 0.52468 0.51131 0.05007  0.01077  -0.00554 798 PHE A CE1 
913  C CE2 . PHE A 180 ? 0.70339 0.60726 0.54184 0.04976  0.03323  -0.00810 798 PHE A CE2 
914  C CZ  . PHE A 180 ? 0.66789 0.57348 0.53805 0.05497  0.02703  -0.01484 798 PHE A CZ  
915  N N   . THR A 181 ? 0.66261 0.55152 0.51414 0.00543  -0.00126 0.00721  799 THR A N   
916  C CA  . THR A 181 ? 0.68056 0.56094 0.52702 -0.00167 -0.00108 -0.00005 799 THR A CA  
917  C C   . THR A 181 ? 0.68954 0.57909 0.52589 -0.00617 -0.01594 -0.01029 799 THR A C   
918  O O   . THR A 181 ? 0.66822 0.55237 0.48104 -0.00682 -0.01623 -0.01495 799 THR A O   
919  C CB  . THR A 181 ? 0.70830 0.58662 0.58523 -0.00841 0.00895  -0.00173 799 THR A CB  
920  O OG1 . THR A 181 ? 0.69251 0.56526 0.56958 -0.00306 0.02363  0.01366  799 THR A OG1 
921  C CG2 . THR A 181 ? 0.75664 0.62330 0.63844 -0.01535 0.00945  -0.01487 799 THR A CG2 
922  N N   . TYR A 182 ? 0.64823 0.55545 0.50201 -0.00864 -0.02823 -0.01301 800 TYR A N   
923  C CA  . TYR A 182 ? 0.66271 0.58496 0.50157 -0.01220 -0.04698 -0.02037 800 TYR A CA  
924  C C   . TYR A 182 ? 0.68636 0.60895 0.49296 -0.00490 -0.05198 -0.00584 800 TYR A C   
925  O O   . TYR A 182 ? 0.73195 0.65856 0.50628 -0.00686 -0.05609 -0.00914 800 TYR A O   
926  C CB  . TYR A 182 ? 0.63335 0.57852 0.50610 -0.01494 -0.06249 -0.02202 800 TYR A CB  
927  C CG  . TYR A 182 ? 0.65976 0.62743 0.51590 -0.01610 -0.08799 -0.02337 800 TYR A CG  
928  C CD1 . TYR A 182 ? 0.68715 0.66594 0.53145 -0.02606 -0.10160 -0.04570 800 TYR A CD1 
929  C CD2 . TYR A 182 ? 0.67833 0.65712 0.53207 -0.00674 -0.09964 -0.00234 800 TYR A CD2 
930  C CE1 . TYR A 182 ? 0.77034 0.77518 0.59037 -0.02655 -0.12776 -0.04618 800 TYR A CE1 
931  C CE2 . TYR A 182 ? 0.69268 0.69528 0.52926 -0.00657 -0.12479 0.00344  800 TYR A CE2 
932  C CZ  . TYR A 182 ? 0.73352 0.75136 0.54832 -0.01643 -0.13959 -0.01802 800 TYR A CZ  
933  O OH  . TYR A 182 ? 0.78344 0.83035 0.57243 -0.01559 -0.16754 -0.01126 800 TYR A OH  
934  N N   . GLN A 183 ? 0.67740 0.59600 0.49483 0.00351  -0.04971 0.00976  801 GLN A N   
935  C CA  . GLN A 183 ? 0.69511 0.61230 0.49671 0.00953  -0.05479 0.02674  801 GLN A CA  
936  C C   . GLN A 183 ? 0.65242 0.55587 0.42783 0.00855  -0.04283 0.02831  801 GLN A C   
937  O O   . GLN A 183 ? 0.66505 0.57368 0.41830 0.00878  -0.04528 0.03949  801 GLN A O   
938  C CB  . GLN A 183 ? 0.72210 0.63336 0.55141 0.01840  -0.05348 0.03650  801 GLN A CB  
939  C CG  . GLN A 183 ? 0.69723 0.62577 0.55941 0.02258  -0.06587 0.04061  801 GLN A CG  
940  C CD  . GLN A 183 ? 0.68085 0.60162 0.57475 0.03304  -0.06066 0.04441  801 GLN A CD  
941  O OE1 . GLN A 183 ? 0.70508 0.61610 0.60441 0.03876  -0.06442 0.05705  801 GLN A OE1 
942  N NE2 . GLN A 183 ? 0.64827 0.57351 0.56645 0.03561  -0.05005 0.03273  801 GLN A NE2 
943  N N   . VAL A 184 ? 0.64553 0.53427 0.42587 0.00818  -0.02926 0.02060  802 VAL A N   
944  C CA  . VAL A 184 ? 0.62652 0.50533 0.39270 0.00777  -0.01851 0.02168  802 VAL A CA  
945  C C   . VAL A 184 ? 0.67153 0.55799 0.41422 0.00298  -0.01572 0.01227  802 VAL A C   
946  O O   . VAL A 184 ? 0.72708 0.61688 0.45145 0.00366  -0.00985 0.01972  802 VAL A O   
947  C CB  . VAL A 184 ? 0.68985 0.55596 0.46800 0.00885  -0.00846 0.01636  802 VAL A CB  
948  C CG1 . VAL A 184 ? 0.64046 0.50023 0.41333 0.00857  0.00136  0.01597  802 VAL A CG1 
949  C CG2 . VAL A 184 ? 0.68043 0.54181 0.47003 0.01454  -0.01068 0.02225  802 VAL A CG2 
950  N N   . ALA A 185 ? 0.65158 0.54255 0.39669 -0.00224 -0.01894 -0.00582 803 ALA A N   
951  C CA  . ALA A 185 ? 0.69068 0.58923 0.41263 -0.00692 -0.01733 -0.02412 803 ALA A CA  
952  C C   . ALA A 185 ? 0.76381 0.68339 0.45024 -0.00630 -0.02833 -0.01533 803 ALA A C   
953  O O   . ALA A 185 ? 0.80707 0.73421 0.46073 -0.00642 -0.01975 -0.02048 803 ALA A O   
954  C CB  . ALA A 185 ? 0.69218 0.59107 0.43380 -0.01424 -0.02278 -0.04799 803 ALA A CB  
955  N N   . ARG A 186 ? 0.71164 0.64292 0.40502 -0.00449 -0.04604 0.00013  804 ARG A N   
956  C CA  . ARG A 186 ? 0.74950 0.70186 0.41199 -0.00214 -0.05856 0.01831  804 ARG A CA  
957  C C   . ARG A 186 ? 0.69546 0.64170 0.34704 0.00276  -0.04451 0.04459  804 ARG A C   
958  O O   . ARG A 186 ? 0.70801 0.67001 0.32147 0.00330  -0.04146 0.05618  804 ARG A O   
959  C CB  . ARG A 186 ? 0.73358 0.69852 0.42026 0.00077  -0.08096 0.03304  804 ARG A CB  
960  C CG  . ARG A 186 ? 0.69562 0.67720 0.39465 -0.00537 -0.09939 0.01081  804 ARG A CG  
961  C CD  . ARG A 186 ? 0.79427 0.79856 0.44641 -0.01095 -0.11138 -0.00661 804 ARG A CD  
962  N NE  . ARG A 186 ? 0.85560 0.88263 0.52501 -0.01703 -0.13812 -0.02393 804 ARG A NE  
963  C CZ  . ARG A 186 ? 0.93642 0.98281 0.57640 -0.02484 -0.15269 -0.05338 804 ARG A CZ  
964  N NH1 . ARG A 186 ? 0.98993 1.03513 0.57747 -0.02608 -0.13927 -0.07003 804 ARG A NH1 
965  N NH2 . ARG A 186 ? 0.90412 0.97281 0.57090 -0.03147 -0.18045 -0.06921 804 ARG A NH2 
966  N N   . GLY A 187 ? 0.66494 0.59068 0.35022 0.00586  -0.03557 0.05397  805 GLY A N   
967  C CA  . GLY A 187 ? 0.74163 0.66070 0.42966 0.00831  -0.02290 0.07606  805 GLY A CA  
968  C C   . GLY A 187 ? 0.76632 0.68682 0.43351 0.00599  -0.00216 0.06681  805 GLY A C   
969  O O   . GLY A 187 ? 0.77163 0.70273 0.42046 0.00652  0.00880  0.08546  805 GLY A O   
970  N N   . MET A 188 ? 0.74746 0.65818 0.42227 0.00414  0.00562  0.04009  806 MET A N   
971  C CA  . MET A 188 ? 0.74805 0.65951 0.41317 0.00383  0.02670  0.02787  806 MET A CA  
972  C C   . MET A 188 ? 0.79853 0.73115 0.41569 0.00240  0.03113  0.01663  806 MET A C   
973  O O   . MET A 188 ? 0.85985 0.80218 0.45880 0.00398  0.05195  0.01831  806 MET A O   
974  C CB  . MET A 188 ? 0.75247 0.64751 0.44358 0.00345  0.03174  0.00446  806 MET A CB  
975  C CG  . MET A 188 ? 0.73957 0.61909 0.46789 0.00609  0.03079  0.01576  806 MET A CG  
976  S SD  . MET A 188 ? 0.78749 0.66963 0.53216 0.00811  0.04175  0.03878  806 MET A SD  
977  C CE  . MET A 188 ? 0.73070 0.62153 0.46966 0.00954  0.06765  0.02565  806 MET A CE  
978  N N   . GLU A 189 ? 0.75591 0.69917 0.35255 -0.00051 0.01180  0.00360  807 GLU A N   
979  C CA  . GLU A 189 ? 0.78086 0.74968 0.32334 -0.00193 0.00946  -0.00812 807 GLU A CA  
980  C C   . GLU A 189 ? 0.80180 0.79034 0.31125 0.00173  0.01448  0.02908  807 GLU A C   
981  O O   . GLU A 189 ? 0.84442 0.85196 0.30912 0.00295  0.03157  0.02610  807 GLU A O   
982  C CB  . GLU A 189 ? 0.74558 0.72611 0.28070 -0.00637 -0.01969 -0.02411 807 GLU A CB  
983  C CG  . GLU A 189 ? 0.81301 0.82503 0.28608 -0.00807 -0.02902 -0.03842 807 GLU A CG  
984  C CD  . GLU A 189 ? 0.85112 0.88325 0.31941 -0.01159 -0.06504 -0.04106 807 GLU A CD  
985  O OE1 . GLU A 189 ? 0.83492 0.85430 0.35419 -0.01489 -0.07862 -0.04766 807 GLU A OE1 
986  O OE2 . GLU A 189 ? 0.93858 1.00296 0.35199 -0.01068 -0.07961 -0.03494 807 GLU A OE2 
987  N N   . PHE A 190 ? 0.85172 0.83620 0.38546 0.00399  0.00195  0.06513  808 PHE A N   
988  C CA  . PHE A 190 ? 0.89355 0.89266 0.40949 0.00720  0.00783  0.10785  808 PHE A CA  
989  C C   . PHE A 190 ? 0.83270 0.82801 0.35623 0.00761  0.04090  0.11738  808 PHE A C   
990  O O   . PHE A 190 ? 0.87032 0.88837 0.35365 0.00889  0.05837  0.13458  808 PHE A O   
991  C CB  . PHE A 190 ? 0.83402 0.82158 0.39374 0.00997  -0.00959 0.14106  808 PHE A CB  
992  C CG  . PHE A 190 ? 0.85759 0.85507 0.41420 0.01288  -0.00321 0.19024  808 PHE A CG  
993  C CD1 . PHE A 190 ? 0.88040 0.90821 0.38735 0.01556  -0.01388 0.21572  808 PHE A CD1 
994  C CD2 . PHE A 190 ? 0.88487 0.86315 0.49019 0.01245  0.01252  0.21257  808 PHE A CD2 
995  C CE1 . PHE A 190 ? 0.97958 1.01680 0.48633 0.01848  -0.00621 0.26840  808 PHE A CE1 
996  C CE2 . PHE A 190 ? 0.88790 0.87345 0.50107 0.01381  0.02024  0.26116  808 PHE A CE2 
997  C CZ  . PHE A 190 ? 0.95621 0.97066 0.52004 0.01720  0.01241  0.29210  808 PHE A CZ  
998  N N   . LEU A 191 ? 0.81483 0.78517 0.39069 0.00682  0.04997  0.10804  809 LEU A N   
999  C CA  . LEU A 191 ? 0.82721 0.79625 0.42482 0.00695  0.07836  0.11831  809 LEU A CA  
1000 C C   . LEU A 191 ? 0.86771 0.85388 0.42754 0.00825  0.10361  0.09401  809 LEU A C   
1001 O O   . LEU A 191 ? 0.89052 0.89367 0.44017 0.00946  0.13052  0.11190  809 LEU A O   
1002 C CB  . LEU A 191 ? 0.75775 0.70089 0.41635 0.00625  0.07667  0.10848  809 LEU A CB  
1003 C CG  . LEU A 191 ? 0.70196 0.62821 0.40164 0.00562  0.05711  0.12811  809 LEU A CG  
1004 C CD1 . LEU A 191 ? 0.68066 0.58726 0.42985 0.00512  0.05508  0.11532  809 LEU A CD1 
1005 C CD2 . LEU A 191 ? 0.65841 0.59228 0.36873 0.00471  0.06299  0.16943  809 LEU A CD2 
1006 N N   . ALA A 192 ? 0.85802 0.84014 0.40172 0.00805  0.09746  0.05229  810 ALA A N   
1007 C CA  . ALA A 192 ? 0.84910 0.84500 0.35991 0.01012  0.12097  0.02046  810 ALA A CA  
1008 C C   . ALA A 192 ? 0.93266 0.96301 0.37016 0.01126  0.12807  0.03038  810 ALA A C   
1009 O O   . ALA A 192 ? 0.96866 1.01802 0.38035 0.01466  0.16015  0.02630  810 ALA A O   
1010 C CB  . ALA A 192 ? 0.81739 0.79903 0.33290 0.00835  0.10853  -0.02634 810 ALA A CB  
1011 N N   . SER A 193 ? 0.96352 1.00559 0.36694 0.00943  0.09892  0.04551  811 SER A N   
1012 C CA  . SER A 193 ? 1.05827 1.13740 0.38648 0.01130  0.10001  0.06248  811 SER A CA  
1013 C C   . SER A 193 ? 1.09967 1.18814 0.43182 0.01233  0.12655  0.11134  811 SER A C   
1014 O O   . SER A 193 ? 1.17215 1.27669 0.45804 0.01055  0.13858  0.11707  811 SER A O   
1015 C CB  . SER A 193 ? 1.04409 1.12876 0.35680 0.00916  0.05823  0.07704  811 SER A CB  
1016 O OG  . SER A 193 ? 1.00354 1.07749 0.36132 0.01065  0.04702  0.12477  811 SER A OG  
1017 N N   . LYS A 194 ? 1.05761 1.12828 0.45421 0.01283  0.13397  0.14317  812 LYS A N   
1018 C CA  . LYS A 194 ? 1.15976 1.23932 0.57673 0.01254  0.16125  0.18963  812 LYS A CA  
1019 C C   . LYS A 194 ? 1.15950 1.23967 0.60718 0.01400  0.20089  0.17440  812 LYS A C   
1020 O O   . LYS A 194 ? 1.12824 1.21453 0.61211 0.01274  0.22567  0.21155  812 LYS A O   
1021 C CB  . LYS A 194 ? 1.12046 1.17738 0.60323 0.01040  0.14390  0.23064  812 LYS A CB  
1022 C CG  . LYS A 194 ? 1.11259 1.16782 0.58106 0.01096  0.10621  0.24856  812 LYS A CG  
1023 C CD  . LYS A 194 ? 1.21492 1.28738 0.64474 0.00945  0.10467  0.27695  812 LYS A CD  
1024 C CE  . LYS A 194 ? 1.25608 1.32848 0.66999 0.01241  0.06496  0.28464  812 LYS A CE  
1025 N NZ  . LYS A 194 ? 1.30986 1.38574 0.73233 0.01403  0.05993  0.33519  812 LYS A NZ  
1026 N N   . ASN A 195 ? 1.14167 1.21489 0.58597 0.01608  0.20662  0.12099  813 ASN A N   
1027 C CA  . ASN A 195 ? 1.15547 1.22700 0.64123 0.01894  0.24099  0.10153  813 ASN A CA  
1028 C C   . ASN A 195 ? 1.06654 1.11530 0.64358 0.01581  0.23854  0.12407  813 ASN A C   
1029 O O   . ASN A 195 ? 1.07380 1.13153 0.69519 0.01662  0.26838  0.13675  813 ASN A O   
1030 C CB  . ASN A 195 ? 1.24522 1.35402 0.68897 0.02314  0.28522  0.11219  813 ASN A CB  
1031 C CG  . ASN A 195 ? 1.42756 1.55376 0.79783 0.02349  0.28809  0.06424  813 ASN A CG  
1032 O OD1 . ASN A 195 ? 1.47739 1.59517 0.85148 0.03018  0.29762  0.01385  813 ASN A OD1 
1033 N ND2 . ASN A 195 ? 1.53264 1.67322 0.84076 0.01609  0.27871  0.07817  813 ASN A ND2 
1034 N N   . CYS A 196 ? 0.95767 0.97964 0.56412 0.01225  0.20242  0.12691  814 CYS A N   
1035 C CA  . CYS A 196 ? 0.90934 0.90860 0.59469 0.00939  0.19235  0.13661  814 CYS A CA  
1036 C C   . CYS A 196 ? 0.86273 0.84104 0.57137 0.01190  0.17948  0.09683  814 CYS A C   
1037 O O   . CYS A 196 ? 0.84515 0.81111 0.52805 0.01176  0.15612  0.07666  814 CYS A O   
1038 C CB  . CYS A 196 ? 0.90483 0.88948 0.60734 0.00499  0.16358  0.16582  814 CYS A CB  
1039 S SG  . CYS A 196 ? 0.87893 0.83225 0.65749 0.00223  0.13820  0.15766  814 CYS A SG  
1040 N N   . VAL A 197 ? 0.84091 0.81746 0.60272 0.01437  0.19509  0.08878  815 VAL A N   
1041 C CA  . VAL A 197 ? 0.78515 0.74175 0.58175 0.01746  0.18173  0.06248  815 VAL A CA  
1042 C C   . VAL A 197 ? 0.78206 0.72378 0.62922 0.01378  0.15707  0.07987  815 VAL A C   
1043 O O   . VAL A 197 ? 0.83455 0.78413 0.72590 0.01070  0.16345  0.10245  815 VAL A O   
1044 C CB  . VAL A 197 ? 0.77904 0.74429 0.60935 0.02438  0.21033  0.04437  815 VAL A CB  
1045 C CG1 . VAL A 197 ? 0.81010 0.75421 0.67855 0.02866  0.19456  0.02388  815 VAL A CG1 
1046 C CG2 . VAL A 197 ? 0.80115 0.78332 0.57801 0.02851  0.23818  0.02154  815 VAL A CG2 
1047 N N   . HIS A 198 ? 0.75607 0.67810 0.59820 0.01359  0.12955  0.06809  816 HIS A N   
1048 C CA  . HIS A 198 ? 0.71889 0.62887 0.59497 0.01051  0.10510  0.08005  816 HIS A CA  
1049 C C   . HIS A 198 ? 0.71142 0.62249 0.64556 0.01261  0.10337  0.07931  816 HIS A C   
1050 O O   . HIS A 198 ? 0.73244 0.64673 0.70820 0.00839  0.09562  0.09384  816 HIS A O   
1051 C CB  . HIS A 198 ? 0.65354 0.54688 0.50463 0.01078  0.08054  0.06810  816 HIS A CB  
1052 C CG  . HIS A 198 ? 0.70663 0.58985 0.57969 0.00834  0.05794  0.07661  816 HIS A CG  
1053 N ND1 . HIS A 198 ? 0.71351 0.59381 0.62571 0.00901  0.04664  0.07460  816 HIS A ND1 
1054 C CD2 . HIS A 198 ? 0.71836 0.59493 0.58176 0.00602  0.04410  0.08456  816 HIS A CD2 
1055 C CE1 . HIS A 198 ? 0.70828 0.58019 0.62897 0.00657  0.02745  0.07644  816 HIS A CE1 
1056 N NE2 . HIS A 198 ? 0.71537 0.58321 0.61072 0.00520  0.02713  0.08245  816 HIS A NE2 
1057 N N   . ARG A 199 ? 0.72001 0.62857 0.66313 0.01902  0.10799  0.06267  817 ARG A N   
1058 C CA  . ARG A 199 ? 0.75261 0.66539 0.75139 0.02395  0.10611  0.06267  817 ARG A CA  
1059 C C   . ARG A 199 ? 0.73685 0.64057 0.75019 0.02365  0.07343  0.06567  817 ARG A C   
1060 O O   . ARG A 199 ? 0.75355 0.66181 0.80607 0.02892  0.06540  0.06712  817 ARG A O   
1061 C CB  . ARG A 199 ? 0.74713 0.68083 0.79806 0.02258  0.12379  0.07690  817 ARG A CB  
1062 C CG  . ARG A 199 ? 0.86409 0.81310 0.89944 0.02431  0.16203  0.07544  817 ARG A CG  
1063 C CD  . ARG A 199 ? 0.94057 0.91209 1.02581 0.02012  0.18076  0.09745  817 ARG A CD  
1064 N NE  . ARG A 199 ? 0.95876 0.94200 1.12159 0.02430  0.17984  0.09868  817 ARG A NE  
1065 C CZ  . ARG A 199 ? 1.00036 1.00291 1.20251 0.03165  0.21154  0.09499  817 ARG A CZ  
1066 N NH1 . ARG A 199 ? 1.04247 1.05472 1.20593 0.03538  0.24891  0.08658  817 ARG A NH1 
1067 N NH2 . ARG A 199 ? 0.94822 0.96317 1.22922 0.03607  0.20548  0.09861  817 ARG A NH2 
1068 N N   . ASP A 200 ? 0.73701 0.63043 0.71980 0.01885  0.05453  0.06646  818 ASP A N   
1069 C CA  . ASP A 200 ? 0.69837 0.58589 0.68454 0.01947  0.02627  0.06483  818 ASP A CA  
1070 C C   . ASP A 200 ? 0.70380 0.57749 0.64161 0.01880  0.01715  0.05763  818 ASP A C   
1071 O O   . ASP A 200 ? 0.67200 0.54151 0.60298 0.01702  -0.00116 0.05530  818 ASP A O   
1072 C CB  . ASP A 200 ? 0.66504 0.55965 0.68835 0.01377  0.01041  0.07059  818 ASP A CB  
1073 C CG  . ASP A 200 ? 0.70602 0.60263 0.73739 0.01615  -0.01888 0.06469  818 ASP A CG  
1074 O OD1 . ASP A 200 ? 0.69333 0.58735 0.70245 0.02310  -0.02389 0.06292  818 ASP A OD1 
1075 O OD2 . ASP A 200 ? 0.66691 0.56857 0.72693 0.01085  -0.03720 0.06195  818 ASP A OD2 
1076 N N   . LEU A 201 ? 0.70568 0.57352 0.61383 0.02023  0.03006  0.05113  819 LEU A N   
1077 C CA  . LEU A 201 ? 0.70686 0.56525 0.57955 0.01941  0.02193  0.04500  819 LEU A CA  
1078 C C   . LEU A 201 ? 0.73124 0.58557 0.60359 0.02357  0.00886  0.04456  819 LEU A C   
1079 O O   . LEU A 201 ? 0.67952 0.53352 0.56755 0.02805  0.01220  0.04731  819 LEU A O   
1080 C CB  . LEU A 201 ? 0.63765 0.49361 0.48603 0.01845  0.03561  0.03559  819 LEU A CB  
1081 C CG  . LEU A 201 ? 0.69703 0.54761 0.51865 0.01641  0.02659  0.03032  819 LEU A CG  
1082 C CD1 . LEU A 201 ? 0.62007 0.47292 0.43338 0.01430  0.01682  0.03767  819 LEU A CD1 
1083 C CD2 . LEU A 201 ? 0.74451 0.59523 0.54833 0.01395  0.03530  0.01700  819 LEU A CD2 
1084 N N   . ALA A 202 ? 0.70256 0.55484 0.55805 0.02309  -0.00450 0.04247  820 ALA A N   
1085 C CA  . ALA A 202 ? 0.69943 0.55293 0.54452 0.02737  -0.01631 0.04320  820 ALA A CA  
1086 C C   . ALA A 202 ? 0.71905 0.57049 0.54299 0.02659  -0.02293 0.03473  820 ALA A C   
1087 O O   . ALA A 202 ? 0.68933 0.53769 0.51858 0.02325  -0.02329 0.03109  820 ALA A O   
1088 C CB  . ALA A 202 ? 0.63967 0.50291 0.50537 0.03019  -0.03113 0.04767  820 ALA A CB  
1089 N N   . ALA A 203 ? 0.68204 0.53618 0.48502 0.03064  -0.02613 0.03375  821 ALA A N   
1090 C CA  . ALA A 203 ? 0.68875 0.54297 0.47514 0.03194  -0.02860 0.02260  821 ALA A CA  
1091 C C   . ALA A 203 ? 0.72904 0.58321 0.52500 0.03173  -0.04303 0.00960  821 ALA A C   
1092 O O   . ALA A 203 ? 0.73565 0.58440 0.53562 0.03182  -0.04343 -0.00110 821 ALA A O   
1093 C CB  . ALA A 203 ? 0.65496 0.51656 0.41587 0.03704  -0.02478 0.02546  821 ALA A CB  
1094 N N   . ARG A 204 ? 0.70184 0.56195 0.51003 0.03135  -0.05606 0.00982  822 ARG A N   
1095 C CA  . ARG A 204 ? 0.73443 0.59411 0.56310 0.02873  -0.07219 -0.00540 822 ARG A CA  
1096 C C   . ARG A 204 ? 0.73631 0.58527 0.60112 0.02227  -0.06704 -0.00149 822 ARG A C   
1097 O O   . ARG A 204 ? 0.69139 0.53448 0.58174 0.01925  -0.07736 -0.01384 822 ARG A O   
1098 C CB  . ARG A 204 ? 0.69953 0.57245 0.54100 0.02865  -0.09005 -0.00437 822 ARG A CB  
1099 C CG  . ARG A 204 ? 0.72441 0.59985 0.59985 0.02564  -0.08340 0.01413  822 ARG A CG  
1100 C CD  . ARG A 204 ? 0.70154 0.59417 0.59685 0.02737  -0.10244 0.01830  822 ARG A CD  
1101 N NE  . ARG A 204 ? 0.69767 0.59361 0.62700 0.02749  -0.09008 0.03662  822 ARG A NE  
1102 C CZ  . ARG A 204 ? 0.71888 0.61620 0.64036 0.03399  -0.08060 0.05166  822 ARG A CZ  
1103 N NH1 . ARG A 204 ? 0.67374 0.57038 0.55487 0.03970  -0.08208 0.05583  822 ARG A NH1 
1104 N NH2 . ARG A 204 ? 0.69308 0.59244 0.65171 0.03507  -0.06733 0.06277  822 ARG A NH2 
1105 N N   . ASN A 205 ? 0.70679 0.55369 0.57483 0.02010  -0.05121 0.01529  823 ASN A N   
1106 C CA  . ASN A 205 ? 0.67653 0.51763 0.56872 0.01495  -0.04337 0.02557  823 ASN A CA  
1107 C C   . ASN A 205 ? 0.69751 0.53344 0.57006 0.01651  -0.03431 0.02994  823 ASN A C   
1108 O O   . ASN A 205 ? 0.71174 0.54841 0.58737 0.01369  -0.02494 0.04443  823 ASN A O   
1109 C CB  . ASN A 205 ? 0.67894 0.52769 0.58800 0.01177  -0.03200 0.04026  823 ASN A CB  
1110 C CG  . ASN A 205 ? 0.69653 0.55235 0.64760 0.00825  -0.04225 0.03992  823 ASN A CG  
1111 O OD1 . ASN A 205 ? 0.68227 0.53377 0.66079 0.00428  -0.05540 0.03237  823 ASN A OD1 
1112 N ND2 . ASN A 205 ? 0.70243 0.56947 0.66661 0.00967  -0.03706 0.04657  823 ASN A ND2 
1113 N N   . VAL A 206 ? 0.67035 0.50481 0.52282 0.02140  -0.03714 0.01837  824 VAL A N   
1114 C CA  . VAL A 206 ? 0.64513 0.47777 0.49024 0.02363  -0.03271 0.02049  824 VAL A CA  
1115 C C   . VAL A 206 ? 0.70439 0.53052 0.56319 0.02838  -0.03999 0.00534  824 VAL A C   
1116 O O   . VAL A 206 ? 0.74927 0.57815 0.59463 0.03242  -0.04304 -0.01199 824 VAL A O   
1117 C CB  . VAL A 206 ? 0.64715 0.48688 0.46617 0.02520  -0.02483 0.01991  824 VAL A CB  
1118 C CG1 . VAL A 206 ? 0.72344 0.56566 0.54422 0.02745  -0.02392 0.02019  824 VAL A CG1 
1119 C CG2 . VAL A 206 ? 0.61667 0.45974 0.42812 0.02101  -0.01694 0.02873  824 VAL A CG2 
1120 N N   . LEU A 207 ? 0.65802 0.47640 0.54376 0.02882  -0.04208 0.01213  825 LEU A N   
1121 C CA  . LEU A 207 ? 0.66852 0.47807 0.57754 0.03491  -0.04679 -0.00396 825 LEU A CA  
1122 C C   . LEU A 207 ? 0.68639 0.50251 0.59118 0.04137  -0.04116 -0.00159 825 LEU A C   
1123 O O   . LEU A 207 ? 0.68995 0.51581 0.58071 0.03919  -0.03793 0.01542  825 LEU A O   
1124 C CB  . LEU A 207 ? 0.68096 0.47540 0.63826 0.03230  -0.05306 0.00440  825 LEU A CB  
1125 C CG  . LEU A 207 ? 0.77560 0.56519 0.75365 0.02420  -0.05928 0.00269  825 LEU A CG  
1126 C CD1 . LEU A 207 ? 0.72137 0.49416 0.75869 0.02090  -0.06339 0.01305  825 LEU A CD1 
1127 C CD2 . LEU A 207 ? 0.83516 0.62768 0.79980 0.02533  -0.06862 -0.02957 825 LEU A CD2 
1128 N N   . LEU A 208 ? 0.71415 0.52712 0.63395 0.04951  -0.04020 -0.02209 826 LEU A N   
1129 C CA  . LEU A 208 ? 0.72383 0.54598 0.65233 0.05692  -0.03388 -0.02159 826 LEU A CA  
1130 C C   . LEU A 208 ? 0.72953 0.53888 0.70979 0.06487  -0.03775 -0.02656 826 LEU A C   
1131 O O   . LEU A 208 ? 0.77633 0.57409 0.77345 0.06949  -0.03775 -0.05358 826 LEU A O   
1132 C CB  . LEU A 208 ? 0.75684 0.59241 0.65751 0.06161  -0.02189 -0.04091 826 LEU A CB  
1133 C CG  . LEU A 208 ? 0.81729 0.66973 0.72490 0.06514  -0.01266 -0.03351 826 LEU A CG  
1134 C CD1 . LEU A 208 ? 0.74259 0.60290 0.63661 0.05596  -0.01675 -0.01055 826 LEU A CD1 
1135 C CD2 . LEU A 208 ? 0.84920 0.71574 0.73533 0.07014  0.00415  -0.04982 826 LEU A CD2 
1136 N N   . ALA A 209 ? 0.68673 0.49859 0.69381 0.06687  -0.04253 -0.00131 827 ALA A N   
1137 C CA  . ALA A 209 ? 0.76482 0.56547 0.83065 0.07641  -0.04655 0.00138  827 ALA A CA  
1138 C C   . ALA A 209 ? 0.75217 0.56779 0.83541 0.08770  -0.03880 -0.01065 827 ALA A C   
1139 O O   . ALA A 209 ? 0.72692 0.56287 0.77803 0.08606  -0.03098 -0.01477 827 ALA A O   
1140 C CB  . ALA A 209 ? 0.71420 0.51328 0.80135 0.07382  -0.05761 0.04267  827 ALA A CB  
1141 N N   . GLN A 210 ? 0.81411 0.61942 0.95776 0.09940  -0.03961 -0.01530 828 GLN A N   
1142 C CA  . GLN A 210 ? 0.82956 0.65099 1.00331 0.11198  -0.03021 -0.02659 828 GLN A CA  
1143 C C   . GLN A 210 ? 0.77134 0.61913 0.94437 0.11016  -0.03865 0.00481  828 GLN A C   
1144 O O   . GLN A 210 ? 0.76839 0.61878 0.92695 0.10240  -0.05417 0.03679  828 GLN A O   
1145 C CB  . GLN A 210 ? 0.85225 0.65553 1.10251 0.12633  -0.03028 -0.03595 828 GLN A CB  
1146 N N   . GLY A 211 ? 0.75000 0.62031 0.94029 0.11739  -0.02787 -0.00629 829 GLY A N   
1147 C CA  . GLY A 211 ? 0.72741 0.62667 0.90816 0.11158  -0.03509 0.01340  829 GLY A CA  
1148 C C   . GLY A 211 ? 0.69261 0.59791 0.80637 0.09640  -0.03115 0.01121  829 GLY A C   
1149 O O   . GLY A 211 ? 0.69362 0.61849 0.79642 0.08842  -0.04074 0.02592  829 GLY A O   
1150 N N   . LYS A 212 ? 0.70812 0.59727 0.78107 0.09250  -0.01942 -0.00762 830 LYS A N   
1151 C CA  . LYS A 212 ? 0.68081 0.57312 0.69716 0.08031  -0.01427 -0.00893 830 LYS A CA  
1152 C C   . LYS A 212 ? 0.72612 0.61825 0.71920 0.06913  -0.03091 0.01416  830 LYS A C   
1153 O O   . LYS A 212 ? 0.67923 0.58497 0.65256 0.06061  -0.03173 0.01896  830 LYS A O   
1154 C CB  . LYS A 212 ? 0.70642 0.62149 0.72124 0.07969  0.00232  -0.01602 830 LYS A CB  
1155 C CG  . LYS A 212 ? 0.83273 0.75211 0.85723 0.09111  0.02504  -0.04006 830 LYS A CG  
1156 C CD  . LYS A 212 ? 0.92968 0.87218 0.94474 0.08866  0.04672  -0.04134 830 LYS A CD  
1157 C CE  . LYS A 212 ? 1.02994 0.98059 1.04470 0.10135  0.07321  -0.06544 830 LYS A CE  
1158 N NZ  . LYS A 212 ? 1.06996 1.04885 1.09126 0.10109  0.09952  -0.06125 830 LYS A NZ  
1159 N N   . ILE A 213 ? 0.66752 0.54392 0.66463 0.06899  -0.04230 0.02713  831 ILE A N   
1160 C CA  . ILE A 213 ? 0.67064 0.54927 0.64289 0.06024  -0.05462 0.04994  831 ILE A CA  
1161 C C   . ILE A 213 ? 0.68935 0.55252 0.62670 0.05262  -0.04880 0.04562  831 ILE A C   
1162 O O   . ILE A 213 ? 0.76428 0.60956 0.71514 0.05477  -0.04708 0.03990  831 ILE A O   
1163 C CB  . ILE A 213 ? 0.74513 0.62258 0.74889 0.06554  -0.06953 0.07690  831 ILE A CB  
1164 C CG1 . ILE A 213 ? 0.78827 0.68704 0.83023 0.07349  -0.07953 0.08449  831 ILE A CG1 
1165 C CG2 . ILE A 213 ? 0.72959 0.61170 0.69694 0.05701  -0.07774 0.10074  831 ILE A CG2 
1166 C CD1 . ILE A 213 ? 0.86820 0.76687 0.95008 0.08184  -0.09574 0.11555  831 ILE A CD1 
1167 N N   . VAL A 214 ? 0.69492 0.56561 0.59477 0.04374  -0.04663 0.04650  832 VAL A N   
1168 C CA  . VAL A 214 ? 0.70581 0.56587 0.57888 0.03745  -0.04074 0.04393  832 VAL A CA  
1169 C C   . VAL A 214 ? 0.71394 0.56751 0.59061 0.03514  -0.04551 0.06424  832 VAL A C   
1170 O O   . VAL A 214 ? 0.74119 0.60486 0.61568 0.03494  -0.05283 0.08429  832 VAL A O   
1171 C CB  . VAL A 214 ? 0.74384 0.61288 0.58657 0.03023  -0.03564 0.03908  832 VAL A CB  
1172 C CG1 . VAL A 214 ? 0.76691 0.62941 0.58863 0.02470  -0.03114 0.04307  832 VAL A CG1 
1173 C CG2 . VAL A 214 ? 0.64467 0.51531 0.48628 0.03144  -0.02595 0.02381  832 VAL A CG2 
1174 N N   . LYS A 215 ? 0.68596 0.52556 0.56934 0.03313  -0.04180 0.06105  833 LYS A N   
1175 C CA  . LYS A 215 ? 0.69555 0.52998 0.58848 0.02903  -0.04148 0.08216  833 LYS A CA  
1176 C C   . LYS A 215 ? 0.72853 0.56121 0.60746 0.02286  -0.03365 0.07478  833 LYS A C   
1177 O O   . LYS A 215 ? 0.74183 0.56509 0.63640 0.02274  -0.03551 0.05936  833 LYS A O   
1178 C CB  . LYS A 215 ? 0.68446 0.50245 0.62656 0.03260  -0.04687 0.08822  833 LYS A CB  
1179 C CG  . LYS A 215 ? 0.74092 0.55856 0.71094 0.04167  -0.05444 0.09293  833 LYS A CG  
1180 C CD  . LYS A 215 ? 0.73830 0.56528 0.71343 0.04280  -0.06055 0.13093  833 LYS A CD  
1181 C CE  . LYS A 215 ? 0.71954 0.54843 0.73193 0.05354  -0.07075 0.13775  833 LYS A CE  
1182 N NZ  . LYS A 215 ? 0.68511 0.52950 0.69606 0.05582  -0.08133 0.17871  833 LYS A NZ  
1183 N N   . ILE A 216 ? 0.75867 0.60246 0.60996 0.01847  -0.02582 0.08395  834 ILE A N   
1184 C CA  . ILE A 216 ? 0.71106 0.55511 0.55949 0.01416  -0.01668 0.08008  834 ILE A CA  
1185 C C   . ILE A 216 ? 0.72759 0.56521 0.61290 0.01079  -0.01528 0.09433  834 ILE A C   
1186 O O   . ILE A 216 ? 0.75627 0.59364 0.65626 0.01003  -0.01427 0.11774  834 ILE A O   
1187 C CB  . ILE A 216 ? 0.71057 0.56799 0.52597 0.01162  -0.00529 0.08314  834 ILE A CB  
1188 C CG1 . ILE A 216 ? 0.68650 0.54800 0.47770 0.01281  -0.00818 0.06599  834 ILE A CG1 
1189 C CG2 . ILE A 216 ? 0.71105 0.56999 0.53469 0.00906  0.00687  0.08075  834 ILE A CG2 
1190 C CD1 . ILE A 216 ? 0.72310 0.59657 0.48393 0.01007  -0.00007 0.06180  834 ILE A CD1 
1191 N N   . CYS A 217 ? 0.67842 0.51240 0.58354 0.00842  -0.01630 0.08280  835 CYS A N   
1192 C CA  . CYS A 217 ? 0.70533 0.53449 0.65707 0.00315  -0.01683 0.09235  835 CYS A CA  
1193 C C   . CYS A 217 ? 0.69909 0.53760 0.66105 -0.00015 -0.01165 0.08749  835 CYS A C   
1194 O O   . CYS A 217 ? 0.65769 0.50338 0.59140 0.00293  -0.00796 0.07742  835 CYS A O   
1195 C CB  . CYS A 217 ? 0.70987 0.52313 0.69655 0.00399  -0.03314 0.07609  835 CYS A CB  
1196 S SG  . CYS A 217 ? 0.75741 0.57154 0.73040 0.00700  -0.04731 0.04009  835 CYS A SG  
1197 N N   . ASP A 218 ? 0.77204 0.61059 0.78423 -0.00648 -0.01155 0.09636  836 ASP A N   
1198 C CA  . ASP A 218 ? 0.76825 0.61766 0.80880 -0.00967 -0.01178 0.09101  836 ASP A CA  
1199 C C   . ASP A 218 ? 0.76151 0.60406 0.86394 -0.01677 -0.02774 0.08525  836 ASP A C   
1200 O O   . ASP A 218 ? 0.78532 0.62368 0.93107 -0.02341 -0.02022 0.10531  836 ASP A O   
1201 C CB  . ASP A 218 ? 0.79136 0.65725 0.83664 -0.01160 0.01378  0.11215  836 ASP A CB  
1202 C CG  . ASP A 218 ? 0.81283 0.69299 0.88878 -0.01184 0.01492  0.10557  836 ASP A CG  
1203 O OD1 . ASP A 218 ? 0.79966 0.67839 0.89574 -0.01190 -0.00809 0.08844  836 ASP A OD1 
1204 O OD2 . ASP A 218 ? 0.83622 0.73133 0.91562 -0.01090 0.03844  0.11676  836 ASP A OD2 
1205 N N   . PHE A 219 ? 0.72483 0.56702 0.83186 -0.01565 -0.05031 0.05825  837 PHE A N   
1206 C CA  . PHE A 219 ? 0.77067 0.60789 0.93703 -0.02330 -0.07024 0.04388  837 PHE A CA  
1207 C C   . PHE A 219 ? 0.78126 0.63402 1.01122 -0.03233 -0.06577 0.05858  837 PHE A C   
1208 O O   . PHE A 219 ? 0.77647 0.62320 1.07384 -0.04243 -0.07101 0.06164  837 PHE A O   
1209 C CB  . PHE A 219 ? 0.83058 0.66959 0.97369 -0.01893 -0.09690 0.00892  837 PHE A CB  
1210 C CG  . PHE A 219 ? 0.87105 0.69353 0.97859 -0.01246 -0.10218 -0.01095 837 PHE A CG  
1211 C CD1 . PHE A 219 ? 0.98148 0.78692 1.12885 -0.01605 -0.11480 -0.03111 837 PHE A CD1 
1212 C CD2 . PHE A 219 ? 0.85075 0.67484 0.89386 -0.00279 -0.09301 -0.01063 837 PHE A CD2 
1213 C CE1 . PHE A 219 ? 1.02617 0.81775 1.14740 -0.00823 -0.11646 -0.05149 837 PHE A CE1 
1214 C CE2 . PHE A 219 ? 0.89900 0.71177 0.91732 0.00369  -0.09480 -0.02808 837 PHE A CE2 
1215 C CZ  . PHE A 219 ? 0.98421 0.78140 1.04033 0.00194  -0.10564 -0.04897 837 PHE A CZ  
1216 N N   . GLY A 220 ? 0.74337 0.61586 0.96181 -0.02886 -0.05484 0.06779  838 GLY A N   
1217 C CA  . GLY A 220 ? 0.74058 0.63218 1.02394 -0.03582 -0.04505 0.08389  838 GLY A CA  
1218 C C   . GLY A 220 ? 0.78582 0.68421 1.13681 -0.04450 -0.07521 0.06569  838 GLY A C   
1219 O O   . GLY A 220 ? 0.81750 0.72367 1.15324 -0.04048 -0.10320 0.04168  838 GLY A O   
1220 N N   . LEU A 221 ? 0.85522 0.75233 1.28355 -0.05711 -0.07065 0.07817  839 LEU A N   
1221 C CA  . LEU A 221 ? 0.87639 0.78109 1.38367 -0.06833 -0.10076 0.05872  839 LEU A CA  
1222 C C   . LEU A 221 ? 0.88414 0.77154 1.36983 -0.06794 -0.13688 0.01790  839 LEU A C   
1223 O O   . LEU A 221 ? 0.91986 0.81807 1.44843 -0.07451 -0.17040 -0.00955 839 LEU A O   
1224 C CB  . LEU A 221 ? 0.91004 0.81221 1.51153 -0.08349 -0.08540 0.08255  839 LEU A CB  
1225 C CG  . LEU A 221 ? 0.93486 0.86571 1.59749 -0.08869 -0.05705 0.11555  839 LEU A CG  
1226 C CD1 . LEU A 221 ? 0.92992 0.89145 1.62952 -0.08812 -0.08040 0.09852  839 LEU A CD1 
1227 C CD2 . LEU A 221 ? 0.95646 0.89284 1.55582 -0.07831 -0.01375 0.14667  839 LEU A CD2 
1228 N N   . ALA A 222 ? 0.86111 0.72493 1.28269 -0.06003 -0.13105 0.01125  840 ALA A N   
1229 C CA  . ALA A 222 ? 0.88640 0.73400 1.28477 -0.05765 -0.15816 -0.02910 840 ALA A CA  
1230 C C   . ALA A 222 ? 0.89049 0.75164 1.20778 -0.04543 -0.17442 -0.05118 840 ALA A C   
1231 O O   . ALA A 222 ? 0.98188 0.83221 1.25745 -0.03980 -0.18835 -0.08202 840 ALA A O   
1232 C CB  . ALA A 222 ? 0.89610 0.71360 1.27826 -0.05420 -0.14210 -0.02348 840 ALA A CB  
1233 N N   . ARG A 223 ? 0.83187 0.71670 1.12904 -0.04039 -0.17040 -0.03427 841 ARG A N   
1234 C CA  . ARG A 223 ? 0.85383 0.75554 1.09077 -0.03012 -0.18933 -0.04840 841 ARG A CA  
1235 C C   . ARG A 223 ? 0.83225 0.76408 1.11778 -0.03395 -0.21372 -0.04855 841 ARG A C   
1236 O O   . ARG A 223 ? 0.80307 0.74631 1.14994 -0.03935 -0.20017 -0.02476 841 ARG A O   
1237 C CB  . ARG A 223 ? 0.87937 0.78044 1.04984 -0.01814 -0.16351 -0.02546 841 ARG A CB  
1238 C CG  . ARG A 223 ? 0.90691 0.82486 1.02227 -0.00753 -0.18037 -0.03152 841 ARG A CG  
1239 C CD  . ARG A 223 ? 0.91584 0.82813 0.97509 0.00261  -0.15461 -0.01134 841 ARG A CD  
1240 N NE  . ARG A 223 ? 0.91521 0.80746 0.92640 0.00560  -0.14152 -0.02011 841 ARG A NE  
1241 C CZ  . ARG A 223 ? 0.89597 0.77242 0.90379 0.00457  -0.11542 -0.00685 841 ARG A CZ  
1242 N NH1 . ARG A 223 ? 0.90161 0.77974 0.94219 0.00070  -0.09696 0.01448  841 ARG A NH1 
1243 N NH2 . ARG A 223 ? 0.85421 0.71658 0.82546 0.00810  -0.10770 -0.01498 841 ARG A NH2 
1244 N N   . ASP A 224 ? 0.83073 0.77890 1.08971 -0.03061 -0.24984 -0.07505 842 ASP A N   
1245 C CA  . ASP A 224 ? 0.87999 0.86187 1.18296 -0.03295 -0.28112 -0.07593 842 ASP A CA  
1246 C C   . ASP A 224 ? 0.85984 0.85962 1.12173 -0.01881 -0.27398 -0.04759 842 ASP A C   
1247 O O   . ASP A 224 ? 0.90874 0.92277 1.11124 -0.00892 -0.29539 -0.05327 842 ASP A O   
1248 C CB  . ASP A 224 ? 0.95664 0.95116 1.24978 -0.03638 -0.32756 -0.11911 842 ASP A CB  
1249 C CG  . ASP A 224 ? 1.04945 1.08206 1.40293 -0.04147 -0.36653 -0.12218 842 ASP A CG  
1250 O OD1 . ASP A 224 ? 1.06187 1.10625 1.49336 -0.04659 -0.35475 -0.09474 842 ASP A OD1 
1251 O OD2 . ASP A 224 ? 1.11953 1.17373 1.44183 -0.03967 -0.40897 -0.15198 842 ASP A OD2 
1252 N N   . ILE A 225 ? 0.76838 0.76765 1.06521 -0.01750 -0.24162 -0.01568 843 ILE A N   
1253 C CA  . ILE A 225 ? 0.79406 0.80429 1.06595 -0.00399 -0.22928 0.01051  843 ILE A CA  
1254 C C   . ILE A 225 ? 0.81426 0.86031 1.12214 0.00078  -0.26393 0.01645  843 ILE A C   
1255 O O   . ILE A 225 ? 0.85684 0.91235 1.14367 0.01393  -0.26110 0.03801  843 ILE A O   
1256 C CB  . ILE A 225 ? 0.75260 0.75424 1.05613 -0.00361 -0.18463 0.03588  843 ILE A CB  
1257 C CG1 . ILE A 225 ? 0.76423 0.78387 1.16767 -0.01394 -0.18164 0.04326  843 ILE A CG1 
1258 C CG2 . ILE A 225 ? 0.71295 0.68341 0.97069 -0.00620 -0.15417 0.03428  843 ILE A CG2 
1259 C CD1 . ILE A 225 ? 0.78091 0.80036 1.21319 -0.01148 -0.13574 0.06779  843 ILE A CD1 
1260 N N   . MET A 226 ? 0.85800 0.92473 1.22534 -0.00963 -0.29865 -0.00156 844 MET A N   
1261 C CA  . MET A 226 ? 0.92140 1.02783 1.32648 -0.00549 -0.33927 0.00293  844 MET A CA  
1262 C C   . MET A 226 ? 0.94818 1.06819 1.27205 0.00270  -0.37883 -0.01199 844 MET A C   
1263 O O   . MET A 226 ? 0.99671 1.14950 1.32590 0.01202  -0.40901 0.00332  844 MET A O   
1264 C CB  . MET A 226 ? 0.97856 1.10572 1.48690 -0.02164 -0.36389 -0.01251 844 MET A CB  
1265 C CG  . MET A 226 ? 1.04434 1.16256 1.63607 -0.03081 -0.32196 0.00548  844 MET A CG  
1266 S SD  . MET A 226 ? 1.18696 1.31928 1.89995 -0.05440 -0.34443 -0.01475 844 MET A SD  
1267 C CE  . MET A 226 ? 1.20178 1.39031 1.98196 -0.05154 -0.40003 -0.01509 844 MET A CE  
1268 N N   . HIS A 227 ? 0.94063 1.03896 1.19087 0.00049  -0.37872 -0.03990 845 HIS A N   
1269 C CA  . HIS A 227 ? 0.98877 1.10156 1.15154 0.00875  -0.40992 -0.05632 845 HIS A CA  
1270 C C   . HIS A 227 ? 1.01629 1.10237 1.08523 0.01862  -0.37627 -0.04893 845 HIS A C   
1271 O O   . HIS A 227 ? 1.08797 1.17617 1.08030 0.02253  -0.38880 -0.07176 845 HIS A O   
1272 C CB  . HIS A 227 ? 1.00929 1.12951 1.17594 -0.00301 -0.44790 -0.10736 845 HIS A CB  
1273 C CG  . HIS A 227 ? 0.99826 1.14448 1.26879 -0.01588 -0.48250 -0.11835 845 HIS A CG  
1274 N ND1 . HIS A 227 ? 0.98103 1.10961 1.33680 -0.03348 -0.47483 -0.13789 845 HIS A ND1 
1275 C CD2 . HIS A 227 ? 1.01284 1.20334 1.32343 -0.01398 -0.52534 -0.10975 845 HIS A CD2 
1276 C CE1 . HIS A 227 ? 0.97618 1.13692 1.42302 -0.04321 -0.50993 -0.14282 845 HIS A CE1 
1277 N NE2 . HIS A 227 ? 0.99214 1.19204 1.41373 -0.03136 -0.54258 -0.12722 845 HIS A NE2 
1278 N N   . ASP A 228 ? 0.98084 1.04406 1.05711 0.02251  -0.33298 -0.01938 846 ASP A N   
1279 C CA  . ASP A 228 ? 0.96060 1.00066 0.96275 0.03079  -0.30076 -0.00878 846 ASP A CA  
1280 C C   . ASP A 228 ? 0.94065 0.98972 0.93439 0.04373  -0.29128 0.03234  846 ASP A C   
1281 O O   . ASP A 228 ? 0.93062 0.97896 0.98615 0.04463  -0.27638 0.05409  846 ASP A O   
1282 C CB  . ASP A 228 ? 0.94402 0.94912 0.96181 0.02380  -0.26064 -0.01193 846 ASP A CB  
1283 C CG  . ASP A 228 ? 0.97563 0.95945 0.92191 0.03035  -0.23280 -0.00829 846 ASP A CG  
1284 O OD1 . ASP A 228 ? 0.97738 0.96590 0.88828 0.04047  -0.22462 0.01618  846 ASP A OD1 
1285 O OD2 . ASP A 228 ? 1.00462 0.96728 0.93779 0.02530  -0.21910 -0.02830 846 ASP A OD2 
1286 N N   . SER A 229 ? 0.94667 1.00410 0.86750 0.05418  -0.29738 0.04334  847 SER A N   
1287 C CA  . SER A 229 ? 0.97551 1.04041 0.89305 0.06692  -0.29085 0.08599  847 SER A CA  
1288 C C   . SER A 229 ? 0.92235 0.95600 0.86278 0.06784  -0.24573 0.10390  847 SER A C   
1289 O O   . SER A 229 ? 0.93685 0.97203 0.90896 0.07657  -0.23770 0.13551  847 SER A O   
1290 C CB  . SER A 229 ? 1.06588 1.14445 0.89664 0.07676  -0.30060 0.09745  847 SER A CB  
1291 O OG  . SER A 229 ? 1.09178 1.14621 0.86691 0.07454  -0.27024 0.08319  847 SER A OG  
1292 N N   . ASN A 230 ? 0.84153 0.84778 0.76959 0.05955  -0.21789 0.08333  848 ASN A N   
1293 C CA  . ASN A 230 ? 0.82145 0.80148 0.76665 0.05930  -0.17890 0.09461  848 ASN A CA  
1294 C C   . ASN A 230 ? 0.75976 0.73988 0.78122 0.05653  -0.16830 0.09912  848 ASN A C   
1295 O O   . ASN A 230 ? 0.74186 0.70505 0.77992 0.05827  -0.13767 0.10779  848 ASN A O   
1296 C CB  . ASN A 230 ? 0.82275 0.77916 0.73231 0.05188  -0.15713 0.07287  848 ASN A CB  
1297 C CG  . ASN A 230 ? 0.95923 0.91580 0.79831 0.05584  -0.15852 0.06860  848 ASN A CG  
1298 O OD1 . ASN A 230 ? 0.95781 0.92062 0.77010 0.06419  -0.15647 0.09221  848 ASN A OD1 
1299 N ND2 . ASN A 230 ? 1.12795 1.07798 0.94168 0.05047  -0.15949 0.04019  848 ASN A ND2 
1300 N N   . TYR A 231 ? 0.75979 0.76028 0.82986 0.05197  -0.19165 0.09131  849 TYR A N   
1301 C CA  . TYR A 231 ? 0.73091 0.73771 0.88041 0.04955  -0.17956 0.09724  849 TYR A CA  
1302 C C   . TYR A 231 ? 0.75978 0.79727 0.96072 0.05819  -0.20702 0.11618  849 TYR A C   
1303 O O   . TYR A 231 ? 0.83980 0.90204 1.04133 0.05669  -0.24717 0.10990  849 TYR A O   
1304 C CB  . TYR A 231 ? 0.69893 0.70515 0.88084 0.03537  -0.18014 0.07617  849 TYR A CB  
1305 C CG  . TYR A 231 ? 0.69816 0.67553 0.83873 0.02859  -0.15311 0.06363  849 TYR A CG  
1306 C CD1 . TYR A 231 ? 0.72034 0.68581 0.79877 0.02695  -0.16301 0.04680  849 TYR A CD1 
1307 C CD2 . TYR A 231 ? 0.68305 0.64820 0.84602 0.02512  -0.11750 0.06926  849 TYR A CD2 
1308 C CE1 . TYR A 231 ? 0.71208 0.65365 0.76118 0.02223  -0.14057 0.03791  849 TYR A CE1 
1309 C CE2 . TYR A 231 ? 0.65490 0.59772 0.77985 0.01987  -0.09720 0.06164  849 TYR A CE2 
1310 C CZ  . TYR A 231 ? 0.68781 0.61854 0.76041 0.01858  -0.10999 0.04704  849 TYR A CZ  
1311 O OH  . TYR A 231 ? 0.68568 0.59648 0.72879 0.01476  -0.09187 0.04186  849 TYR A OH  
1312 N N   . VAL A 232 ? 0.75076 0.84186 0.83147 0.07134  -0.20794 0.04096  850 VAL A N   
1313 C CA  . VAL A 232 ? 0.75312 0.85779 0.87036 0.09834  -0.23264 0.03346  850 VAL A CA  
1314 C C   . VAL A 232 ? 0.74570 0.90536 0.96565 0.08679  -0.22706 0.01521  850 VAL A C   
1315 O O   . VAL A 232 ? 0.73927 0.91559 0.98460 0.06342  -0.18654 0.01600  850 VAL A O   
1316 C CB  . VAL A 232 ? 0.76031 0.83720 0.84318 0.11769  -0.21696 0.04483  850 VAL A CB  
1317 C CG1 . VAL A 232 ? 0.80083 0.88110 0.91258 0.15063  -0.25040 0.03712  850 VAL A CG1 
1318 C CG2 . VAL A 232 ? 0.76651 0.78676 0.75605 0.12209  -0.20852 0.06058  850 VAL A CG2 
1319 N N   . SER A 233 ? 0.78182 0.96637 1.06053 0.10414  -0.26705 -0.00429 851 SER A N   
1320 C CA  . SER A 233 ? 0.79455 1.03511 1.19018 0.09434  -0.26018 -0.02917 851 SER A CA  
1321 C C   . SER A 233 ? 0.85098 1.10562 1.27776 0.10017  -0.23114 -0.03069 851 SER A C   
1322 O O   . SER A 233 ? 0.88165 1.11330 1.27627 0.13038  -0.24931 -0.02506 851 SER A O   
1323 C CB  . SER A 233 ? 0.76923 1.03287 1.22973 0.11962  -0.31811 -0.05735 851 SER A CB  
1324 O OG  . SER A 233 ? 0.73485 1.05665 1.32697 0.11221  -0.31033 -0.08872 851 SER A OG  
1325 N N   . LYS A 234 ? 0.87364 1.15984 1.35681 0.07122  -0.18354 -0.03783 852 LYS A N   
1326 C CA  . LYS A 234 ? 0.94378 1.25203 1.47218 0.07504  -0.15381 -0.04645 852 LYS A CA  
1327 C C   . LYS A 234 ? 1.00158 1.35506 1.62452 0.04367  -0.11160 -0.06753 852 LYS A C   
1328 O O   . LYS A 234 ? 1.02131 1.36069 1.61064 0.01179  -0.07055 -0.05500 852 LYS A O   
1329 C CB  . LYS A 234 ? 0.96895 1.23999 1.40984 0.07341  -0.12121 -0.02195 852 LYS A CB  
1330 C CG  . LYS A 234 ? 0.97851 1.26457 1.45490 0.08876  -0.10493 -0.03080 852 LYS A CG  
1331 C CD  . LYS A 234 ? 0.99022 1.23229 1.37988 0.09853  -0.09197 -0.00909 852 LYS A CD  
1332 C CE  . LYS A 234 ? 0.97403 1.23355 1.39177 0.09492  -0.05107 -0.01783 852 LYS A CE  
1333 N NZ  . LYS A 234 ? 0.96218 1.22611 1.36510 0.06275  -0.00505 -0.01761 852 LYS A NZ  
1334 N N   . GLY A 235 ? 0.99972 1.40211 1.73975 0.05342  -0.12142 -0.10116 853 GLY A N   
1335 C CA  . GLY A 235 ? 0.99380 1.44115 1.84025 0.02205  -0.07616 -0.12725 853 GLY A CA  
1336 C C   . GLY A 235 ? 0.98978 1.44419 1.87155 -0.00216 -0.08047 -0.13445 853 GLY A C   
1337 O O   . GLY A 235 ? 0.97851 1.44627 1.90201 0.01684  -0.13781 -0.15170 853 GLY A O   
1338 N N   . SER A 236 ? 1.04075 1.47963 1.89961 -0.04232 -0.02169 -0.12147 854 SER A N   
1339 C CA  . SER A 236 ? 1.07375 1.51608 1.97535 -0.07084 -0.01475 -0.12867 854 SER A CA  
1340 C C   . SER A 236 ? 1.06778 1.45978 1.85784 -0.07299 -0.04161 -0.09732 854 SER A C   
1341 O O   . SER A 236 ? 1.09892 1.49378 1.92597 -0.08930 -0.05256 -0.10513 854 SER A O   
1342 C CB  . SER A 236 ? 1.15144 1.59260 2.08543 -0.11476 0.06827  -0.13115 854 SER A CB  
1343 O OG  . SER A 236 ? 1.18625 1.62053 2.15598 -0.14512 0.08050  -0.13456 854 SER A OG  
1344 N N   . THR A 237 ? 1.02129 1.36921 1.68649 -0.05768 -0.05159 -0.06634 855 THR A N   
1345 C CA  . THR A 237 ? 0.97725 1.27762 1.54177 -0.06251 -0.06960 -0.04059 855 THR A CA  
1346 C C   . THR A 237 ? 0.91655 1.19128 1.39550 -0.02935 -0.10967 -0.02538 855 THR A C   
1347 O O   . THR A 237 ? 0.92724 1.21503 1.41906 -0.00279 -0.12394 -0.03143 855 THR A O   
1348 C CB  . THR A 237 ? 0.99874 1.25467 1.48878 -0.09253 -0.01665 -0.01751 855 THR A CB  
1349 O OG1 . THR A 237 ? 1.00242 1.21318 1.40160 -0.09320 -0.04123 0.00272  855 THR A OG1 
1350 C CG2 . THR A 237 ? 0.97553 1.21762 1.41398 -0.08512 0.01698  -0.00770 855 THR A CG2 
1351 N N   . PHE A 238 ? 0.85480 1.08903 1.24790 -0.03198 -0.12497 -0.00672 856 PHE A N   
1352 C CA  . PHE A 238 ? 0.76145 0.96477 1.07213 -0.00651 -0.15442 0.00652  856 PHE A CA  
1353 C C   . PHE A 238 ? 0.73790 0.90242 0.96549 -0.01413 -0.12295 0.02573  856 PHE A C   
1354 O O   . PHE A 238 ? 0.75745 0.90186 0.95889 -0.03773 -0.09827 0.03291  856 PHE A O   
1355 C CB  . PHE A 238 ? 0.74387 0.93296 1.02822 -0.00163 -0.19674 0.00541  856 PHE A CB  
1356 C CG  . PHE A 238 ? 0.76594 0.99010 1.12908 0.01124  -0.23725 -0.01859 856 PHE A CG  
1357 C CD1 . PHE A 238 ? 0.77282 1.03020 1.22792 -0.01147 -0.22974 -0.03695 856 PHE A CD1 
1358 C CD2 . PHE A 238 ? 0.77725 0.99522 1.12086 0.04738  -0.28331 -0.02485 856 PHE A CD2 
1359 C CE1 . PHE A 238 ? 0.81305 1.10627 1.35469 0.00248  -0.27155 -0.06663 856 PHE A CE1 
1360 C CE2 . PHE A 238 ? 0.81708 1.06333 1.23003 0.06518  -0.32964 -0.05190 856 PHE A CE2 
1361 C CZ  . PHE A 238 ? 0.81041 1.09902 1.33019 0.04309  -0.32597 -0.07561 856 PHE A CZ  
1362 N N   . LEU A 239 ? 0.66658 0.81562 0.85270 0.00759  -0.12564 0.03220  857 LEU A N   
1363 C CA  . LEU A 239 ? 0.66182 0.78226 0.79089 0.00397  -0.09642 0.04195  857 LEU A CA  
1364 C C   . LEU A 239 ? 0.65296 0.73886 0.71833 0.01982  -0.11182 0.04884  857 LEU A C   
1365 O O   . LEU A 239 ? 0.63783 0.72034 0.69937 0.04014  -0.13433 0.04964  857 LEU A O   
1366 C CB  . LEU A 239 ? 0.64927 0.78941 0.81127 0.01059  -0.06807 0.03700  857 LEU A CB  
1367 C CG  . LEU A 239 ? 0.69642 0.86828 0.92224 -0.00828 -0.03773 0.02681  857 LEU A CG  
1368 C CD1 . LEU A 239 ? 0.68007 0.87577 0.94524 0.00305  -0.01477 0.01717  857 LEU A CD1 
1369 C CD2 . LEU A 239 ? 0.71038 0.85190 0.88857 -0.03404 -0.00762 0.03506  857 LEU A CD2 
1370 N N   . PRO A 240 ? 0.66485 0.71983 0.67883 0.01202  -0.09925 0.05163  858 PRO A N   
1371 C CA  . PRO A 240 ? 0.66108 0.68482 0.62893 0.02369  -0.10492 0.05189  858 PRO A CA  
1372 C C   . PRO A 240 ? 0.67175 0.69134 0.64196 0.03988  -0.08643 0.05172  858 PRO A C   
1373 O O   . PRO A 240 ? 0.66851 0.67187 0.62178 0.04009  -0.06871 0.04571  858 PRO A O   
1374 C CB  . PRO A 240 ? 0.57719 0.57536 0.50916 0.00962  -0.10168 0.04705  858 PRO A CB  
1375 C CG  . PRO A 240 ? 0.62589 0.63050 0.56594 -0.00158 -0.08077 0.04840  858 PRO A CG  
1376 C CD  . PRO A 240 ? 0.61743 0.65920 0.61274 -0.00669 -0.07857 0.05183  858 PRO A CD  
1377 N N   . VAL A 241 ? 0.66947 0.70078 0.66281 0.05646  -0.09482 0.05591  859 VAL A N   
1378 C CA  . VAL A 241 ? 0.66480 0.69625 0.67336 0.07192  -0.07828 0.05598  859 VAL A CA  
1379 C C   . VAL A 241 ? 0.67159 0.66460 0.64239 0.07806  -0.06344 0.05597  859 VAL A C   
1380 O O   . VAL A 241 ? 0.68144 0.67289 0.66292 0.08042  -0.04169 0.04895  859 VAL A O   
1381 C CB  . VAL A 241 ? 0.70670 0.74909 0.74259 0.09253  -0.09931 0.05937  859 VAL A CB  
1382 C CG1 . VAL A 241 ? 0.70733 0.73697 0.74953 0.11151  -0.08601 0.06142  859 VAL A CG1 
1383 C CG2 . VAL A 241 ? 0.67078 0.76068 0.77228 0.08552  -0.10717 0.04961  859 VAL A CG2 
1384 N N   . LYS A 242 ? 0.66465 0.62591 0.59528 0.08019  -0.07238 0.06026  860 LYS A N   
1385 C CA  . LYS A 242 ? 0.75464 0.67772 0.65991 0.08312  -0.05104 0.05669  860 LYS A CA  
1386 C C   . LYS A 242 ? 0.72226 0.64631 0.63683 0.07039  -0.03664 0.03810  860 LYS A C   
1387 O O   . LYS A 242 ? 0.74678 0.64789 0.66427 0.07308  -0.01589 0.02725  860 LYS A O   
1388 C CB  . LYS A 242 ? 0.76953 0.65646 0.62694 0.08488  -0.05778 0.06230  860 LYS A CB  
1389 C CG  . LYS A 242 ? 0.79210 0.65266 0.61825 0.10617  -0.06923 0.07968  860 LYS A CG  
1390 C CD  . LYS A 242 ? 0.82091 0.63327 0.58234 0.10859  -0.06809 0.08456  860 LYS A CD  
1391 C CE  . LYS A 242 ? 0.93024 0.69234 0.63743 0.13447  -0.07336 0.10366  860 LYS A CE  
1392 N NZ  . LYS A 242 ? 1.03601 0.73729 0.66414 0.13631  -0.06051 0.10905  860 LYS A NZ  
1393 N N   . TRP A 243 ? 0.67079 0.61526 0.58978 0.05814  -0.04794 0.03240  861 TRP A N   
1394 C CA  . TRP A 243 ? 0.64898 0.58640 0.56567 0.05189  -0.04329 0.01376  861 TRP A CA  
1395 C C   . TRP A 243 ? 0.69409 0.64707 0.62479 0.05552  -0.03162 0.00975  861 TRP A C   
1396 O O   . TRP A 243 ? 0.67599 0.61634 0.59549 0.05613  -0.03092 -0.00752 861 TRP A O   
1397 C CB  . TRP A 243 ? 0.67779 0.61073 0.57270 0.03824  -0.06436 0.01055  861 TRP A CB  
1398 C CG  . TRP A 243 ? 0.68057 0.59410 0.56315 0.03488  -0.07296 0.00226  861 TRP A CG  
1399 C CD1 . TRP A 243 ? 0.69014 0.58359 0.57308 0.03308  -0.07457 -0.02221 861 TRP A CD1 
1400 C CD2 . TRP A 243 ? 0.69747 0.60849 0.56717 0.03453  -0.08102 0.01383  861 TRP A CD2 
1401 N NE1 . TRP A 243 ? 0.65047 0.53170 0.52573 0.02848  -0.07724 -0.02656 861 TRP A NE1 
1402 C CE2 . TRP A 243 ? 0.68575 0.57457 0.54482 0.02988  -0.08108 -0.00299 861 TRP A CE2 
1403 C CE3 . TRP A 243 ? 0.73790 0.66192 0.60496 0.04008  -0.09098 0.03274  861 TRP A CE3 
1404 C CZ2 . TRP A 243 ? 0.73903 0.61521 0.57430 0.02940  -0.08587 0.00147  861 TRP A CZ2 
1405 C CZ3 . TRP A 243 ? 0.78470 0.69373 0.62505 0.04305  -0.10292 0.03669  861 TRP A CZ3 
1406 C CH2 . TRP A 243 ? 0.80348 0.68734 0.62290 0.03711  -0.09791 0.02267  861 TRP A CH2 
1407 N N   . MET A 244 ? 0.67762 0.65538 0.63183 0.06012  -0.02436 0.02163  862 MET A N   
1408 C CA  . MET A 244 ? 0.69728 0.69292 0.66423 0.06055  -0.00948 0.01710  862 MET A CA  
1409 C C   . MET A 244 ? 0.68066 0.67655 0.67038 0.07597  0.00762  0.00610  862 MET A C   
1410 O O   . MET A 244 ? 0.69798 0.68778 0.70598 0.08651  0.01040  0.01005  862 MET A O   
1411 C CB  . MET A 244 ? 0.68122 0.70976 0.67797 0.05501  -0.00857 0.02854  862 MET A CB  
1412 C CG  . MET A 244 ? 0.65337 0.68317 0.63584 0.03647  -0.01879 0.03502  862 MET A CG  
1413 S SD  . MET A 244 ? 0.70914 0.78140 0.75072 0.02966  -0.02105 0.04060  862 MET A SD  
1414 C CE  . MET A 244 ? 0.71747 0.81355 0.79238 0.02955  0.01565  0.03103  862 MET A CE  
1415 N N   . ALA A 245 ? 0.66439 0.66088 0.64676 0.07820  0.01937  -0.00789 863 ALA A N   
1416 C CA  . ALA A 245 ? 0.69732 0.69948 0.70646 0.09311  0.03518  -0.02215 863 ALA A CA  
1417 C C   . ALA A 245 ? 0.73798 0.77349 0.78980 0.09756  0.04706  -0.01356 863 ALA A C   
1418 O O   . ALA A 245 ? 0.72968 0.78698 0.78910 0.08730  0.04786  -0.00377 863 ALA A O   
1419 C CB  . ALA A 245 ? 0.69765 0.68666 0.67567 0.09715  0.03999  -0.04251 863 ALA A CB  
1420 N N   . PRO A 246 ? 0.70729 0.74684 0.79574 0.11306  0.05581  -0.02030 864 PRO A N   
1421 C CA  . PRO A 246 ? 0.67588 0.74634 0.81221 0.12080  0.06160  -0.01623 864 PRO A CA  
1422 C C   . PRO A 246 ? 0.62885 0.73075 0.77744 0.11307  0.07886  -0.02532 864 PRO A C   
1423 O O   . PRO A 246 ? 0.63228 0.76451 0.81941 0.10913  0.07897  -0.02089 864 PRO A O   
1424 C CB  . PRO A 246 ? 0.69384 0.75395 0.86014 0.13890  0.07004  -0.02656 864 PRO A CB  
1425 C CG  . PRO A 246 ? 0.72359 0.74445 0.86389 0.13806  0.06699  -0.02778 864 PRO A CG  
1426 C CD  . PRO A 246 ? 0.73886 0.75345 0.83580 0.12415  0.06002  -0.03395 864 PRO A CD  
1427 N N   . GLU A 247 ? 0.61765 0.70945 0.73368 0.11167  0.09422  -0.04079 865 GLU A N   
1428 C CA  . GLU A 247 ? 0.65359 0.76333 0.76464 0.10256  0.11956  -0.04826 865 GLU A CA  
1429 C C   . GLU A 247 ? 0.71363 0.82491 0.80571 0.08026  0.12158  -0.03311 865 GLU A C   
1430 O O   . GLU A 247 ? 0.68683 0.82152 0.80205 0.06858  0.14753  -0.03655 865 GLU A O   
1431 C CB  . GLU A 247 ? 0.68225 0.76479 0.73768 0.10926  0.13157  -0.06687 865 GLU A CB  
1432 C CG  . GLU A 247 ? 0.78461 0.82143 0.76076 0.10358  0.11570  -0.06375 865 GLU A CG  
1433 C CD  . GLU A 247 ? 0.79556 0.80916 0.76972 0.11726  0.08922  -0.07508 865 GLU A CD  
1434 O OE1 . GLU A 247 ? 0.74835 0.77728 0.77907 0.12542  0.08576  -0.07596 865 GLU A OE1 
1435 O OE2 . GLU A 247 ? 0.83381 0.80993 0.75149 0.12034  0.07274  -0.08507 865 GLU A OE2 
1436 N N   . SER A 248 ? 0.67771 0.76513 0.73565 0.07308  0.09762  -0.01921 866 SER A N   
1437 C CA  . SER A 248 ? 0.70292 0.79229 0.75250 0.05233  0.09607  -0.00556 866 SER A CA  
1438 C C   . SER A 248 ? 0.63677 0.76579 0.75918 0.05137  0.08532  -0.00035 866 SER A C   
1439 O O   . SER A 248 ? 0.62936 0.78358 0.78878 0.03642  0.09986  -0.00191 866 SER A O   
1440 C CB  . SER A 248 ? 0.74248 0.79397 0.73563 0.04719  0.07063  0.00349  866 SER A CB  
1441 O OG  . SER A 248 ? 0.75904 0.77073 0.68658 0.05158  0.07296  -0.00613 866 SER A OG  
1442 N N   . ILE A 249 ? 0.62913 0.75906 0.77219 0.06841  0.06007  0.00361  867 ILE A N   
1443 C CA  . ILE A 249 ? 0.61094 0.76746 0.81012 0.07517  0.03929  0.00691  867 ILE A CA  
1444 C C   . ILE A 249 ? 0.65365 0.85275 0.92788 0.08028  0.05580  -0.00947 867 ILE A C   
1445 O O   . ILE A 249 ? 0.71684 0.94936 1.04617 0.06986  0.05893  -0.01760 867 ILE A O   
1446 C CB  . ILE A 249 ? 0.60681 0.73794 0.79083 0.09570  0.01274  0.01662  867 ILE A CB  
1447 C CG1 . ILE A 249 ? 0.58517 0.67720 0.70464 0.08886  0.00220  0.02711  867 ILE A CG1 
1448 C CG2 . ILE A 249 ? 0.57179 0.71825 0.79647 0.10896  -0.01688 0.01939  867 ILE A CG2 
1449 C CD1 . ILE A 249 ? 0.61037 0.66807 0.70744 0.10554  -0.00991 0.03570  867 ILE A CD1 
1450 N N   . PHE A 250 ? 0.66854 0.86874 0.95521 0.09597  0.06758  -0.01881 868 PHE A N   
1451 C CA  . PHE A 250 ? 0.64986 0.88997 1.01626 0.10688  0.07590  -0.03711 868 PHE A CA  
1452 C C   . PHE A 250 ? 0.66857 0.93450 1.05586 0.09129  0.12064  -0.05573 868 PHE A C   
1453 O O   . PHE A 250 ? 0.76066 1.06988 1.22906 0.09017  0.13278  -0.07496 868 PHE A O   
1454 C CB  . PHE A 250 ? 0.62688 0.85205 1.00065 0.13315  0.06524  -0.03847 868 PHE A CB  
1455 C CG  . PHE A 250 ? 0.60448 0.78721 0.93651 0.14661  0.03320  -0.01758 868 PHE A CG  
1456 C CD1 . PHE A 250 ? 0.62249 0.80382 0.97145 0.15849  -0.00179 -0.00963 868 PHE A CD1 
1457 C CD2 . PHE A 250 ? 0.58576 0.72668 0.86107 0.14798  0.03919  -0.00917 868 PHE A CD2 
1458 C CE1 . PHE A 250 ? 0.67654 0.80873 0.97088 0.17120  -0.02605 0.01071  868 PHE A CE1 
1459 C CE2 . PHE A 250 ? 0.61570 0.71332 0.85180 0.15699  0.01999  0.00876  868 PHE A CE2 
1460 C CZ  . PHE A 250 ? 0.67602 0.76571 0.91346 0.16840  -0.01048 0.02097  868 PHE A CZ  
1461 N N   . ASP A 251 ? 0.67706 0.91396 0.99205 0.08064  0.14541  -0.05331 869 ASP A N   
1462 C CA  . ASP A 251 ? 0.73198 0.97825 1.04243 0.06815  0.19184  -0.06925 869 ASP A CA  
1463 C C   . ASP A 251 ? 0.77242 0.99041 1.01809 0.04190  0.21491  -0.05856 869 ASP A C   
1464 O O   . ASP A 251 ? 0.81621 1.02460 1.03213 0.03068  0.25847  -0.06787 869 ASP A O   
1465 C CB  . ASP A 251 ? 0.75235 0.98019 1.02555 0.08503  0.20295  -0.08137 869 ASP A CB  
1466 C CG  . ASP A 251 ? 0.72725 0.98162 1.07185 0.10907  0.18884  -0.09428 869 ASP A CG  
1467 O OD1 . ASP A 251 ? 0.70538 1.00332 1.13113 0.11069  0.20178  -0.11139 869 ASP A OD1 
1468 O OD2 . ASP A 251 ? 0.70167 0.93126 1.02638 0.12606  0.16554  -0.08906 869 ASP A OD2 
1469 N N   . ASN A 252 ? 0.79064 0.98885 1.00767 0.03257  0.18835  -0.03924 870 ASN A N   
1470 C CA  . ASN A 252 ? 0.84517 1.01628 1.01384 0.00656  0.20669  -0.02773 870 ASN A CA  
1471 C C   . ASN A 252 ? 0.88007 0.99378 0.93865 0.00479  0.22797  -0.02444 870 ASN A C   
1472 O O   . ASN A 252 ? 0.93844 1.02421 0.95192 -0.01527 0.26462  -0.02022 870 ASN A O   
1473 C CB  . ASN A 252 ? 0.88199 1.09082 1.12754 -0.01562 0.24341  -0.03900 870 ASN A CB  
1474 C CG  . ASN A 252 ? 0.93246 1.11816 1.15457 -0.04314 0.25222  -0.02481 870 ASN A CG  
1475 O OD1 . ASN A 252 ? 0.90612 1.07605 1.10549 -0.04221 0.21239  -0.00960 870 ASN A OD1 
1476 N ND2 . ASN A 252 ? 0.99841 1.17806 1.22493 -0.06876 0.30832  -0.03050 870 ASN A ND2 
1477 N N   . LEU A 253 ? 0.85699 0.94675 0.86973 0.02710  0.20408  -0.02786 871 LEU A N   
1478 C CA  . LEU A 253 ? 0.88679 0.91893 0.79515 0.03402  0.20996  -0.03094 871 LEU A CA  
1479 C C   . LEU A 253 ? 0.88898 0.87887 0.73918 0.03665  0.16916  -0.01936 871 LEU A C   
1480 O O   . LEU A 253 ? 0.85763 0.86022 0.74038 0.04834  0.13513  -0.02042 871 LEU A O   
1481 C CB  . LEU A 253 ? 0.84521 0.88269 0.75619 0.05949  0.21026  -0.05304 871 LEU A CB  
1482 N N   . TYR A 254 ? 0.97203 0.90741 0.73569 0.02551  0.17501  -0.00910 872 TYR A N   
1483 C CA  . TYR A 254 ? 0.96409 0.85577 0.67240 0.02725  0.13579  -0.00097 872 TYR A CA  
1484 C C   . TYR A 254 ? 1.03276 0.85446 0.63061 0.04424  0.12767  -0.01116 872 TYR A C   
1485 O O   . TYR A 254 ? 1.12139 0.89401 0.63854 0.03614  0.15586  -0.00299 872 TYR A O   
1486 C CB  . TYR A 254 ? 0.98215 0.86432 0.68787 0.00055  0.14034  0.02054  872 TYR A CB  
1487 C CG  . TYR A 254 ? 0.95852 0.90057 0.76433 -0.01027 0.12925  0.02670  872 TYR A CG  
1488 C CD1 . TYR A 254 ? 0.98657 0.97764 0.87055 -0.02382 0.15993  0.02558  872 TYR A CD1 
1489 C CD2 . TYR A 254 ? 0.88978 0.83612 0.71078 -0.00530 0.08689  0.02997  872 TYR A CD2 
1490 C CE1 . TYR A 254 ? 0.93862 0.97877 0.90929 -0.02803 0.14102  0.02710  872 TYR A CE1 
1491 C CE2 . TYR A 254 ? 0.84171 0.83334 0.73813 -0.01097 0.07336  0.03486  872 TYR A CE2 
1492 C CZ  . TYR A 254 ? 0.90174 0.93877 0.87071 -0.02037 0.09670  0.03325  872 TYR A CZ  
1493 O OH  . TYR A 254 ? 0.90850 0.98590 0.94899 -0.02042 0.07512  0.03388  872 TYR A OH  
1494 N N   . THR A 255 ? 1.00983 0.82133 0.60217 0.06870  0.08955  -0.03098 873 THR A N   
1495 C CA  . THR A 255 ? 1.08677 0.83164 0.58196 0.09184  0.06755  -0.04871 873 THR A CA  
1496 C C   . THR A 255 ? 1.04570 0.77131 0.54253 0.10364  0.01446  -0.06134 873 THR A C   
1497 O O   . THR A 255 ? 0.94732 0.71192 0.51738 0.09321  0.00162  -0.05587 873 THR A O   
1498 C CB  . THR A 255 ? 1.09433 0.84814 0.59290 0.11648  0.07593  -0.07652 873 THR A CB  
1499 O OG1 . THR A 255 ? 1.05509 0.86371 0.65617 0.12543  0.06038  -0.09241 873 THR A OG1 
1500 C CG2 . THR A 255 ? 1.11638 0.88937 0.61519 0.10503  0.13137  -0.06903 873 THR A CG2 
1501 N N   . THR A 256 ? 0.91106 0.77254 0.55231 0.10661  0.14251  0.04285  874 THR A N   
1502 C CA  . THR A 256 ? 0.93990 0.79832 0.56741 0.10098  0.10685  0.04301  874 THR A CA  
1503 C C   . THR A 256 ? 0.95228 0.80394 0.59845 0.09202  0.07739  0.01072  874 THR A C   
1504 O O   . THR A 256 ? 0.94667 0.79384 0.61872 0.08146  0.05465  0.01225  874 THR A O   
1505 C CB  . THR A 256 ? 1.02306 0.88941 0.57561 0.11534  0.09982  0.05098  874 THR A CB  
1506 O OG1 . THR A 256 ? 1.06649 0.93754 0.60521 0.12410  0.12788  0.09090  874 THR A OG1 
1507 C CG2 . THR A 256 ? 0.99784 0.86349 0.54696 0.10974  0.06033  0.04676  874 THR A CG2 
1508 N N   . LEU A 257 ? 0.91662 0.76702 0.55491 0.09679  0.08072  -0.01755 875 LEU A N   
1509 C CA  . LEU A 257 ? 0.88086 0.72250 0.54669 0.08886  0.05580  -0.04463 875 LEU A CA  
1510 C C   . LEU A 257 ? 0.83921 0.67390 0.56846 0.07692  0.05359  -0.03746 875 LEU A C   
1511 O O   . LEU A 257 ? 0.81275 0.64020 0.56503 0.06851  0.03118  -0.04414 875 LEU A O   
1512 C CB  . LEU A 257 ? 0.92288 0.76333 0.57357 0.09818  0.06175  -0.07797 875 LEU A CB  
1513 C CG  . LEU A 257 ? 1.02182 0.86987 0.60213 0.11144  0.05366  -0.09553 875 LEU A CG  
1514 C CD1 . LEU A 257 ? 1.07226 0.91854 0.64097 0.12165  0.06038  -0.13616 875 LEU A CD1 
1515 C CD2 . LEU A 257 ? 1.01199 0.85943 0.58694 0.10503  0.01521  -0.10047 875 LEU A CD2 
1516 N N   . SER A 258 ? 0.83020 0.66809 0.58982 0.07688  0.07597  -0.02346 876 SER A N   
1517 C CA  . SER A 258 ? 0.79418 0.62852 0.60800 0.06724  0.06724  -0.01741 876 SER A CA  
1518 C C   . SER A 258 ? 0.77302 0.60734 0.58779 0.05984  0.05422  -0.00012 876 SER A C   
1519 O O   . SER A 258 ? 0.77551 0.60597 0.61344 0.05280  0.03693  -0.00102 876 SER A O   
1520 C CB  . SER A 258 ? 0.82757 0.66754 0.68541 0.06933  0.09071  -0.01251 876 SER A CB  
1521 O OG  . SER A 258 ? 0.91261 0.76009 0.75453 0.07552  0.11963  0.00379  876 SER A OG  
1522 N N   . ASP A 259 ? 0.73576 0.57455 0.52450 0.06308  0.06329  0.01648  877 ASP A N   
1523 C CA  . ASP A 259 ? 0.74844 0.58662 0.53958 0.05761  0.05041  0.02995  877 ASP A CA  
1524 C C   . ASP A 259 ? 0.77446 0.60951 0.55065 0.05361  0.02504  0.01927  877 ASP A C   
1525 O O   . ASP A 259 ? 0.71402 0.54743 0.50788 0.04705  0.01358  0.02288  877 ASP A O   
1526 C CB  . ASP A 259 ? 0.78743 0.63020 0.55454 0.06430  0.06370  0.05250  877 ASP A CB  
1527 C CG  . ASP A 259 ? 0.83719 0.68118 0.64271 0.06429  0.08887  0.07124  877 ASP A CG  
1528 O OD1 . ASP A 259 ? 0.78135 0.62416 0.63578 0.05791  0.09041  0.06267  877 ASP A OD1 
1529 O OD2 . ASP A 259 ? 0.80225 0.64883 0.59289 0.07129  0.10606  0.09570  877 ASP A OD2 
1530 N N   . VAL A 260 ? 0.76018 0.59502 0.50811 0.05791  0.01739  0.00418  878 VAL A N   
1531 C CA  . VAL A 260 ? 0.71029 0.54254 0.45829 0.05318  -0.00587 -0.00677 878 VAL A CA  
1532 C C   . VAL A 260 ? 0.81122 0.63561 0.59582 0.04529  -0.01215 -0.01124 878 VAL A C   
1533 O O   . VAL A 260 ? 0.87744 0.70037 0.67547 0.03910  -0.02377 -0.00707 878 VAL A O   
1534 C CB  . VAL A 260 ? 0.78056 0.61432 0.49853 0.05998  -0.01501 -0.02830 878 VAL A CB  
1535 C CG1 . VAL A 260 ? 0.80261 0.63173 0.54341 0.05297  -0.03795 -0.04353 878 VAL A CG1 
1536 C CG2 . VAL A 260 ? 0.77092 0.61496 0.44254 0.06976  -0.01607 -0.01959 878 VAL A CG2 
1537 N N   . TRP A 261 ? 0.80685 0.62717 0.60916 0.04683  -0.00349 -0.01743 879 TRP A N   
1538 C CA  . TRP A 261 ? 0.77281 0.58691 0.60622 0.04222  -0.01061 -0.01540 879 TRP A CA  
1539 C C   . TRP A 261 ? 0.70320 0.52101 0.54273 0.03831  -0.01255 -0.00062 879 TRP A C   
1540 O O   . TRP A 261 ? 0.75439 0.56972 0.59890 0.03465  -0.02155 0.00507  879 TRP A O   
1541 C CB  . TRP A 261 ? 0.76506 0.57695 0.62204 0.04657  -0.00259 -0.02263 879 TRP A CB  
1542 C CG  . TRP A 261 ? 0.78328 0.59011 0.66947 0.04489  -0.01346 -0.01686 879 TRP A CG  
1543 C CD1 . TRP A 261 ? 0.74412 0.55511 0.63699 0.04339  -0.01977 -0.00536 879 TRP A CD1 
1544 C CD2 . TRP A 261 ? 0.78586 0.58278 0.69691 0.04669  -0.02052 -0.02184 879 TRP A CD2 
1545 N NE1 . TRP A 261 ? 0.72870 0.53463 0.63964 0.04548  -0.03135 -0.00019 879 TRP A NE1 
1546 C CE2 . TRP A 261 ? 0.75080 0.54705 0.67740 0.04718  -0.03102 -0.00722 879 TRP A CE2 
1547 C CE3 . TRP A 261 ? 0.83263 0.62076 0.75604 0.04905  -0.01988 -0.03841 879 TRP A CE3 
1548 C CZ2 . TRP A 261 ? 0.75460 0.54123 0.70884 0.05037  -0.03980 -0.00162 879 TRP A CZ2 
1549 C CZ3 . TRP A 261 ? 0.83745 0.61424 0.79823 0.05060  -0.02768 -0.03659 879 TRP A CZ3 
1550 C CH2 . TRP A 261 ? 0.80613 0.58199 0.78207 0.05142  -0.03697 -0.01487 879 TRP A CH2 
1551 N N   . SER A 262 ? 0.64369 0.46747 0.48548 0.03980  -0.00208 0.00513  880 SER A N   
1552 C CA  . SER A 262 ? 0.71880 0.54577 0.57139 0.03694  -0.00468 0.01214  880 SER A CA  
1553 C C   . SER A 262 ? 0.70489 0.53278 0.54330 0.03415  -0.01001 0.01809  880 SER A C   
1554 O O   . SER A 262 ? 0.66985 0.49876 0.51239 0.03225  -0.01471 0.01949  880 SER A O   
1555 C CB  . SER A 262 ? 0.74585 0.57737 0.61678 0.03838  0.00890  0.01638  880 SER A CB  
1556 O OG  . SER A 262 ? 0.80106 0.63429 0.69808 0.04057  0.01499  0.01058  880 SER A OG  
1557 N N   . TYR A 263 ? 0.67236 0.50166 0.49391 0.03537  -0.00975 0.02044  881 TYR A N   
1558 C CA  . TYR A 263 ? 0.67816 0.51050 0.49668 0.03317  -0.01696 0.02549  881 TYR A CA  
1559 C C   . TYR A 263 ? 0.74143 0.57101 0.56873 0.02868  -0.02469 0.02279  881 TYR A C   
1560 O O   . TYR A 263 ? 0.70420 0.53690 0.53976 0.02639  -0.02426 0.02837  881 TYR A O   
1561 C CB  . TYR A 263 ? 0.68846 0.52494 0.48724 0.03728  -0.02164 0.02640  881 TYR A CB  
1562 C CG  . TYR A 263 ? 0.72601 0.56817 0.53087 0.03567  -0.03389 0.02948  881 TYR A CG  
1563 C CD1 . TYR A 263 ? 0.71900 0.56637 0.53291 0.03753  -0.03201 0.04240  881 TYR A CD1 
1564 C CD2 . TYR A 263 ? 0.73369 0.57622 0.54611 0.03242  -0.04751 0.01880  881 TYR A CD2 
1565 C CE1 . TYR A 263 ? 0.72486 0.57953 0.55363 0.03690  -0.04354 0.04505  881 TYR A CE1 
1566 C CE2 . TYR A 263 ? 0.72451 0.57472 0.55495 0.03056  -0.05932 0.02075  881 TYR A CE2 
1567 C CZ  . TYR A 263 ? 0.74555 0.60279 0.58319 0.03321  -0.05740 0.03415  881 TYR A CZ  
1568 O OH  . TYR A 263 ? 0.66529 0.53219 0.52972 0.03216  -0.06949 0.03598  881 TYR A OH  
1569 N N   . GLY A 264 ? 0.70854 0.53194 0.53870 0.02814  -0.02878 0.01563  882 GLY A N   
1570 C CA  . GLY A 264 ? 0.69317 0.51174 0.53909 0.02432  -0.03254 0.01926  882 GLY A CA  
1571 C C   . GLY A 264 ? 0.73233 0.55119 0.57628 0.02541  -0.02789 0.02914  882 GLY A C   
1572 O O   . GLY A 264 ? 0.76055 0.58072 0.60791 0.02377  -0.02459 0.03899  882 GLY A O   
1573 N N   . ILE A 265 ? 0.72377 0.54308 0.56286 0.02928  -0.02747 0.02571  883 ILE A N   
1574 C CA  . ILE A 265 ? 0.70864 0.53111 0.54063 0.03256  -0.02885 0.02929  883 ILE A CA  
1575 C C   . ILE A 265 ? 0.71494 0.54438 0.53984 0.03216  -0.02332 0.02864  883 ILE A C   
1576 O O   . ILE A 265 ? 0.72883 0.56154 0.54085 0.03487  -0.02116 0.03230  883 ILE A O   
1577 C CB  . ILE A 265 ? 0.68939 0.51349 0.53014 0.03645  -0.03382 0.02105  883 ILE A CB  
1578 C CG1 . ILE A 265 ? 0.68006 0.49767 0.53541 0.03812  -0.03706 0.02031  883 ILE A CG1 
1579 C CG2 . ILE A 265 ? 0.70212 0.53151 0.53321 0.04166  -0.04258 0.01980  883 ILE A CG2 
1580 C CD1 . ILE A 265 ? 0.66504 0.47648 0.52014 0.04086  -0.04420 0.03236  883 ILE A CD1 
1581 N N   . LEU A 266 ? 0.69554 0.52747 0.52832 0.03046  -0.01943 0.02495  884 LEU A N   
1582 C CA  . LEU A 266 ? 0.70146 0.53863 0.53840 0.03066  -0.01386 0.02438  884 LEU A CA  
1583 C C   . LEU A 266 ? 0.69573 0.53582 0.53282 0.02886  -0.00962 0.03191  884 LEU A C   
1584 O O   . LEU A 266 ? 0.67123 0.51622 0.50695 0.03111  -0.00220 0.03064  884 LEU A O   
1585 C CB  . LEU A 266 ? 0.73601 0.57385 0.58557 0.03049  -0.01072 0.02614  884 LEU A CB  
1586 C CG  . LEU A 266 ? 0.74111 0.58303 0.60465 0.03119  -0.00627 0.03004  884 LEU A CG  
1587 C CD1 . LEU A 266 ? 0.70802 0.55190 0.58126 0.03328  -0.00167 0.01944  884 LEU A CD1 
1588 C CD2 . LEU A 266 ? 0.81798 0.65906 0.69096 0.03323  -0.00381 0.03884  884 LEU A CD2 
1589 N N   . LEU A 267 ? 0.66409 0.50210 0.50803 0.02521  -0.01332 0.03736  885 LEU A N   
1590 C CA  . LEU A 267 ? 0.69930 0.54112 0.55867 0.02224  -0.00862 0.04507  885 LEU A CA  
1591 C C   . LEU A 267 ? 0.77308 0.61405 0.62238 0.02423  0.00146  0.05399  885 LEU A C   
1592 O O   . LEU A 267 ? 0.75763 0.60516 0.61323 0.02500  0.01470  0.06062  885 LEU A O   
1593 C CB  . LEU A 267 ? 0.74043 0.57979 0.61803 0.01758  -0.01856 0.04431  885 LEU A CB  
1594 C CG  . LEU A 267 ? 0.73187 0.57550 0.61028 0.01848  -0.03032 0.03704  885 LEU A CG  
1595 C CD1 . LEU A 267 ? 0.65785 0.50474 0.56317 0.01438  -0.04281 0.03249  885 LEU A CD1 
1596 C CD2 . LEU A 267 ? 0.70458 0.55585 0.58500 0.02193  -0.02616 0.04109  885 LEU A CD2 
1597 N N   . TRP A 268 ? 0.76361 0.59767 0.59683 0.02682  -0.00340 0.05610  886 TRP A N   
1598 C CA  . TRP A 268 ? 0.74365 0.57758 0.55729 0.03215  0.00412  0.06901  886 TRP A CA  
1599 C C   . TRP A 268 ? 0.75347 0.59634 0.53920 0.03944  0.01016  0.06085  886 TRP A C   
1600 O O   . TRP A 268 ? 0.77765 0.62578 0.54491 0.04471  0.02450  0.07072  886 TRP A O   
1601 C CB  . TRP A 268 ? 0.72364 0.54932 0.52901 0.03560  -0.00728 0.07300  886 TRP A CB  
1602 C CG  . TRP A 268 ? 0.72038 0.54459 0.50648 0.04249  -0.00128 0.09454  886 TRP A CG  
1603 C CD1 . TRP A 268 ? 0.70551 0.52114 0.51186 0.04074  0.00549  0.11731  886 TRP A CD1 
1604 C CD2 . TRP A 268 ? 0.77014 0.60183 0.51205 0.05390  -0.00175 0.09681  886 TRP A CD2 
1605 N NE1 . TRP A 268 ? 0.77794 0.59485 0.55243 0.05102  0.01221  0.14013  886 TRP A NE1 
1606 C CE2 . TRP A 268 ? 0.79750 0.62544 0.52596 0.06015  0.00639  0.12632  886 TRP A CE2 
1607 C CE3 . TRP A 268 ? 0.76607 0.60731 0.48053 0.06026  -0.00936 0.07546  886 TRP A CE3 
1608 C CZ2 . TRP A 268 ? 0.82923 0.66448 0.50484 0.07458  0.00657  0.13676  886 TRP A CZ2 
1609 C CZ3 . TRP A 268 ? 0.80485 0.65356 0.47178 0.07356  -0.01210 0.07867  886 TRP A CZ3 
1610 C CH2 . TRP A 268 ? 0.85191 0.69848 0.49354 0.08157  -0.00458 0.10982  886 TRP A CH2 
1611 N N   . GLU A 269 ? 0.73049 0.57522 0.51550 0.04053  0.00115  0.04194  887 GLU A N   
1612 C CA  . GLU A 269 ? 0.80012 0.65234 0.57065 0.04676  0.00479  0.02642  887 GLU A CA  
1613 C C   . GLU A 269 ? 0.80600 0.66455 0.58828 0.04633  0.02290  0.02790  887 GLU A C   
1614 O O   . GLU A 269 ? 0.79928 0.66492 0.55924 0.05393  0.03503  0.02294  887 GLU A O   
1615 C CB  . GLU A 269 ? 0.78353 0.63456 0.57305 0.04540  -0.00603 0.00782  887 GLU A CB  
1616 C CG  . GLU A 269 ? 0.77295 0.62295 0.55632 0.04869  -0.02266 -0.00102 887 GLU A CG  
1617 C CD  . GLU A 269 ? 0.75391 0.60398 0.56946 0.04674  -0.02840 -0.01873 887 GLU A CD  
1618 O OE1 . GLU A 269 ? 0.73944 0.58489 0.58053 0.04098  -0.02456 -0.01190 887 GLU A OE1 
1619 O OE2 . GLU A 269 ? 0.76040 0.61547 0.57680 0.05177  -0.03597 -0.03975 887 GLU A OE2 
1620 N N   . ILE A 270 ? 0.71720 0.57493 0.53416 0.03910  0.02442  0.03344  888 ILE A N   
1621 C CA  . ILE A 270 ? 0.67901 0.54452 0.52060 0.03902  0.03881  0.03421  888 ILE A CA  
1622 C C   . ILE A 270 ? 0.72498 0.59612 0.56286 0.04042  0.05801  0.04933  888 ILE A C   
1623 O O   . ILE A 270 ? 0.73267 0.61236 0.56490 0.04678  0.07734  0.04552  888 ILE A O   
1624 C CB  . ILE A 270 ? 0.64916 0.51448 0.52789 0.03273  0.02987  0.03871  888 ILE A CB  
1625 C CG1 . ILE A 270 ? 0.62137 0.48259 0.50519 0.03398  0.01972  0.02922  888 ILE A CG1 
1626 C CG2 . ILE A 270 ? 0.67994 0.55539 0.59496 0.03237  0.04182  0.04369  888 ILE A CG2 
1627 C CD1 . ILE A 270 ? 0.66722 0.52901 0.57333 0.03141  0.00952  0.03751  888 ILE A CD1 
1628 N N   . PHE A 271 ? 0.70977 0.57602 0.55510 0.03512  0.05576  0.06669  889 PHE A N   
1629 C CA  . PHE A 271 ? 0.79491 0.66550 0.65444 0.03446  0.07700  0.08702  889 PHE A CA  
1630 C C   . PHE A 271 ? 0.85022 0.72021 0.66118 0.04389  0.09059  0.10031  889 PHE A C   
1631 O O   . PHE A 271 ? 0.93829 0.81162 0.75669 0.04517  0.11412  0.12339  889 PHE A O   
1632 C CB  . PHE A 271 ? 0.75966 0.62441 0.66331 0.02409  0.06791  0.09843  889 PHE A CB  
1633 C CG  . PHE A 271 ? 0.75122 0.62174 0.70051 0.01766  0.05576  0.08782  889 PHE A CG  
1634 C CD1 . PHE A 271 ? 0.75730 0.63969 0.75615 0.01483  0.06921  0.09386  889 PHE A CD1 
1635 C CD2 . PHE A 271 ? 0.74143 0.60749 0.68377 0.01626  0.03156  0.07331  889 PHE A CD2 
1636 C CE1 . PHE A 271 ? 0.74509 0.63515 0.78649 0.01105  0.05277  0.08463  889 PHE A CE1 
1637 C CE2 . PHE A 271 ? 0.73844 0.61135 0.71318 0.01359  0.01806  0.06670  889 PHE A CE2 
1638 C CZ  . PHE A 271 ? 0.74015 0.62531 0.76463 0.01120  0.02566  0.07175  889 PHE A CZ  
1639 N N   . SER A 272 ? 0.79964 0.66670 0.56371 0.05143  0.07620  0.08800  890 SER A N   
1640 C CA  . SER A 272 ? 0.85119 0.72306 0.55706 0.06514  0.08543  0.09315  890 SER A CA  
1641 C C   . SER A 272 ? 0.84886 0.73153 0.52858 0.07446  0.09252  0.06598  890 SER A C   
1642 O O   . SER A 272 ? 0.86679 0.75588 0.48899 0.08845  0.09628  0.06139  890 SER A O   
1643 C CB  . SER A 272 ? 0.89709 0.76162 0.57147 0.06978  0.06027  0.09375  890 SER A CB  
1644 O OG  . SER A 272 ? 0.89999 0.76353 0.57944 0.06805  0.03688  0.06429  890 SER A OG  
1645 N N   . LEU A 273 ? 0.82388 0.70867 0.54511 0.06843  0.09280  0.04707  891 LEU A N   
1646 C CA  . LEU A 273 ? 0.80798 0.70058 0.52196 0.07634  0.09973  0.01780  891 LEU A CA  
1647 C C   . LEU A 273 ? 0.80997 0.70085 0.48846 0.08363  0.07595  -0.00963 891 LEU A C   
1648 O O   . LEU A 273 ? 0.79838 0.69722 0.43727 0.09648  0.08022  -0.03189 891 LEU A O   
1649 C CB  . LEU A 273 ? 0.83208 0.73703 0.52326 0.08690  0.13429  0.02283  891 LEU A CB  
1650 C CG  . LEU A 273 ? 0.88390 0.79346 0.62955 0.07901  0.15940  0.04695  891 LEU A CG  
1651 C CD1 . LEU A 273 ? 0.89170 0.81436 0.61302 0.09043  0.19982  0.05813  891 LEU A CD1 
1652 C CD2 . LEU A 273 ? 0.89132 0.80187 0.70239 0.07150  0.15361  0.03159  891 LEU A CD2 
1653 N N   . GLY A 274 ? 0.80606 0.68778 0.50261 0.07589  0.05052  -0.01049 892 GLY A N   
1654 C CA  . GLY A 274 ? 0.83379 0.71473 0.51848 0.08026  0.02635  -0.03677 892 GLY A CA  
1655 C C   . GLY A 274 ? 0.86118 0.74423 0.49672 0.08887  0.00957  -0.03161 892 GLY A C   
1656 O O   . GLY A 274 ? 0.89180 0.78052 0.50501 0.09792  -0.00912 -0.05888 892 GLY A O   
1657 N N   . GLY A 275 ? 0.83862 0.71745 0.46216 0.08711  0.01321  0.00172  893 GLY A N   
1658 C CA  . GLY A 275 ? 0.89434 0.77408 0.47809 0.09638  -0.00490 0.01188  893 GLY A CA  
1659 C C   . GLY A 275 ? 0.88115 0.75572 0.49615 0.09111  -0.03366 0.00096  893 GLY A C   
1660 O O   . GLY A 275 ? 0.82269 0.69008 0.48772 0.07867  -0.03397 -0.00254 893 GLY A O   
1661 N N   . THR A 276 ? 0.90549 0.78558 0.48999 0.10237  -0.05778 -0.00376 894 THR A N   
1662 C CA  . THR A 276 ? 0.85289 0.72999 0.47437 0.09845  -0.08329 -0.01036 894 THR A CA  
1663 C C   . THR A 276 ? 0.85349 0.71958 0.49173 0.09352  -0.07911 0.02350  894 THR A C   
1664 O O   . THR A 276 ? 0.91627 0.78094 0.52061 0.10158  -0.07420 0.05172  894 THR A O   
1665 C CB  . THR A 276 ? 0.93516 0.82439 0.52803 0.11308  -0.11570 -0.02944 894 THR A CB  
1666 O OG1 . THR A 276 ? 0.93852 0.83729 0.52326 0.11749  -0.12172 -0.06873 894 THR A OG1 
1667 C CG2 . THR A 276 ? 0.93909 0.82721 0.58397 0.10879  -0.14023 -0.03522 894 THR A CG2 
1668 N N   . PRO A 277 ? 0.83326 0.69100 0.52380 0.08142  -0.07846 0.02208  895 PRO A N   
1669 C CA  . PRO A 277 ? 0.81874 0.66544 0.52999 0.07763  -0.07573 0.04663  895 PRO A CA  
1670 C C   . PRO A 277 ? 0.87833 0.72652 0.57681 0.08963  -0.09663 0.05990  895 PRO A C   
1671 O O   . PRO A 277 ? 0.87452 0.73367 0.56228 0.09881  -0.12016 0.04365  895 PRO A O   
1672 C CB  . PRO A 277 ? 0.76880 0.61090 0.52966 0.06684  -0.07514 0.03238  895 PRO A CB  
1673 C CG  . PRO A 277 ? 0.72494 0.57179 0.49069 0.06175  -0.06659 0.01330  895 PRO A CG  
1674 C CD  . PRO A 277 ? 0.76904 0.62639 0.50130 0.07150  -0.07579 -0.00048 895 PRO A CD  
1675 N N   . TYR A 278 ? 0.88507 0.72214 0.59219 0.08985  -0.09004 0.08907  896 TYR A N   
1676 C CA  . TYR A 278 ? 0.87834 0.71371 0.57859 0.10237  -0.10715 0.11159  896 TYR A CA  
1677 C C   . TYR A 278 ? 0.95579 0.80598 0.59343 0.11975  -0.12385 0.11294  896 TYR A C   
1678 O O   . TYR A 278 ? 0.97158 0.83107 0.60876 0.13023  -0.15432 0.10326  896 TYR A O   
1679 C CB  . TYR A 278 ? 0.85175 0.68542 0.60380 0.10131  -0.12581 0.09930  896 TYR A CB  
1680 C CG  . TYR A 278 ? 0.78604 0.60793 0.58818 0.08681  -0.10894 0.09073  896 TYR A CG  
1681 C CD1 . TYR A 278 ? 0.76494 0.57121 0.59517 0.08403  -0.09934 0.11001  896 TYR A CD1 
1682 C CD2 . TYR A 278 ? 0.78501 0.61137 0.60565 0.07726  -0.10265 0.06329  896 TYR A CD2 
1683 C CE1 . TYR A 278 ? 0.75994 0.55710 0.62868 0.07307  -0.08694 0.09620  896 TYR A CE1 
1684 C CE2 . TYR A 278 ? 0.75106 0.56878 0.60412 0.06734  -0.08795 0.05609  896 TYR A CE2 
1685 C CZ  . TYR A 278 ? 0.77239 0.57638 0.64593 0.06568  -0.08151 0.06953  896 TYR A CZ  
1686 O OH  . TYR A 278 ? 0.78462 0.58159 0.68387 0.05785  -0.06973 0.05622  896 TYR A OH  
1687 N N   . PRO A 279 ? 1.01392 0.86823 0.59994 0.12418  -0.10505 0.12261  897 PRO A N   
1688 C CA  . PRO A 279 ? 1.10395 0.97497 0.62066 0.14206  -0.11974 0.11349  897 PRO A CA  
1689 C C   . PRO A 279 ? 1.18344 1.05851 0.66794 0.16144  -0.14544 0.13984  897 PRO A C   
1690 O O   . PRO A 279 ? 1.20675 1.06959 0.70225 0.16387  -0.13643 0.18183  897 PRO A O   
1691 C CB  . PRO A 279 ? 1.07181 0.94394 0.54509 0.14338  -0.08437 0.12792  897 PRO A CB  
1692 C CG  . PRO A 279 ? 0.97879 0.83410 0.49788 0.13026  -0.05713 0.16037  897 PRO A CG  
1693 C CD  . PRO A 279 ? 0.94007 0.78546 0.53011 0.11505  -0.06953 0.14307  897 PRO A CD  
1694 N N   . GLY A 280 ? 1.24957 1.14217 0.69921 0.17605  -0.18016 0.11409  898 GLY A N   
1695 C CA  . GLY A 280 ? 1.31880 1.21954 0.73700 0.19718  -0.21401 0.13433  898 GLY A CA  
1696 C C   . GLY A 280 ? 1.28713 1.18455 0.77992 0.19385  -0.24260 0.13215  898 GLY A C   
1697 O O   . GLY A 280 ? 1.34302 1.25299 0.82195 0.21173  -0.28212 0.13448  898 GLY A O   
1698 N N   . MET A 281 ? 1.18599 1.06872 0.75684 0.17320  -0.22454 0.12646  899 MET A N   
1699 C CA  . MET A 281 ? 1.17387 1.05247 0.82015 0.17018  -0.24299 0.12548  899 MET A CA  
1700 C C   . MET A 281 ? 1.15582 1.04948 0.84580 0.16532  -0.26699 0.07794  899 MET A C   
1701 O O   . MET A 281 ? 1.09249 0.98502 0.80473 0.14968  -0.24883 0.04958  899 MET A O   
1702 C CB  . MET A 281 ? 1.09701 0.95383 0.80160 0.15253  -0.21056 0.13859  899 MET A CB  
1703 C CG  . MET A 281 ? 1.14763 0.98758 0.84456 0.15752  -0.19419 0.18726  899 MET A CG  
1704 S SD  . MET A 281 ? 1.13291 0.94866 0.89794 0.13600  -0.15875 0.19056  899 MET A SD  
1705 C CE  . MET A 281 ? 1.04215 0.85839 0.88660 0.13211  -0.17630 0.16198  899 MET A CE  
1706 N N   . MET A 282 ? 1.17795 1.08608 0.88637 0.17926  -0.30808 0.07156  900 MET A N   
1707 C CA  . MET A 282 ? 1.18707 1.10861 0.96562 0.17325  -0.32974 0.03104  900 MET A CA  
1708 C C   . MET A 282 ? 1.11466 1.02329 0.97967 0.15762  -0.30644 0.03284  900 MET A C   
1709 O O   . MET A 282 ? 1.13814 1.03176 1.01877 0.15841  -0.29325 0.06354  900 MET A O   
1710 C CB  . MET A 282 ? 1.32263 1.26513 1.10765 0.19346  -0.38318 0.02503  900 MET A CB  
1711 C CG  . MET A 282 ? 1.50185 1.45740 1.18528 0.21582  -0.40979 0.03246  900 MET A CG  
1712 S SD  . MET A 282 ? 1.59418 1.56829 1.24008 0.21533  -0.42448 -0.02588 900 MET A SD  
1713 C CE  . MET A 282 ? 1.55925 1.54807 1.33132 0.20485  -0.45515 -0.07190 900 MET A CE  
1714 N N   . VAL A 283 ? 1.02540 0.93966 0.94822 0.14425  -0.29952 -0.00059 901 VAL A N   
1715 C CA  . VAL A 283 ? 0.97227 0.87940 0.97560 0.13309  -0.27891 -0.00245 901 VAL A CA  
1716 C C   . VAL A 283 ? 0.94237 0.86349 1.01036 0.14464  -0.31248 -0.00483 901 VAL A C   
1717 O O   . VAL A 283 ? 0.95992 0.90083 1.07104 0.14688  -0.33943 -0.03253 901 VAL A O   
1718 C CB  . VAL A 283 ? 0.88954 0.79791 0.93109 0.11644  -0.25470 -0.02983 901 VAL A CB  
1719 C CG1 . VAL A 283 ? 0.82531 0.73026 0.94506 0.10901  -0.23319 -0.03105 901 VAL A CG1 
1720 C CG2 . VAL A 283 ? 0.85793 0.75228 0.84273 0.10634  -0.22277 -0.02397 901 VAL A CG2 
1721 N N   . ASP A 284 ? 0.87711 0.78821 0.96029 0.15239  -0.31244 0.02352  902 ASP A N   
1722 C CA  . ASP A 284 ? 0.92949 0.85218 1.08395 0.16434  -0.34155 0.02544  902 ASP A CA  
1723 C C   . ASP A 284 ? 0.93191 0.83580 1.13492 0.16109  -0.31272 0.04319  902 ASP A C   
1724 O O   . ASP A 284 ? 0.92473 0.80952 1.10781 0.14865  -0.27362 0.04721  902 ASP A O   
1725 C CB  . ASP A 284 ? 1.01230 0.94672 1.12151 0.18683  -0.38953 0.04419  902 ASP A CB  
1726 C CG  . ASP A 284 ? 1.05157 0.96727 1.07721 0.19429  -0.37777 0.08610  902 ASP A CG  
1727 O OD1 . ASP A 284 ? 1.02922 0.92183 1.05800 0.18311  -0.33812 0.10237  902 ASP A OD1 
1728 O OD2 . ASP A 284 ? 1.12485 1.05002 1.08224 0.21218  -0.40819 0.10250  902 ASP A OD2 
1729 N N   . SER A 285 ? 0.94526 0.85542 1.21619 0.17347  -0.33435 0.05104  903 SER A N   
1730 C CA  . SER A 285 ? 0.89353 0.78557 1.21791 0.17283  -0.30883 0.06374  903 SER A CA  
1731 C C   . SER A 285 ? 0.91295 0.77902 1.18072 0.17444  -0.29448 0.09760  903 SER A C   
1732 O O   . SER A 285 ? 0.91655 0.76246 1.20686 0.16623  -0.26107 0.09820  903 SER A O   
1733 C CB  . SER A 285 ? 0.85599 0.76053 1.26828 0.18859  -0.33854 0.06800  903 SER A CB  
1734 O OG  . SER A 285 ? 0.95098 0.86330 1.32892 0.20812  -0.38531 0.09481  903 SER A OG  
1735 N N   . THR A 286 ? 0.94505 0.81199 1.14108 0.18550  -0.31819 0.12485  904 THR A N   
1736 C CA  . THR A 286 ? 0.98508 0.82828 1.13102 0.18567  -0.29945 0.16034  904 THR A CA  
1737 C C   . THR A 286 ? 0.97705 0.80798 1.08535 0.16544  -0.25922 0.14561  904 THR A C   
1738 O O   . THR A 286 ? 1.00684 0.81550 1.12483 0.15815  -0.23212 0.15780  904 THR A O   
1739 C CB  . THR A 286 ? 1.07809 0.92848 1.14605 0.20317  -0.32823 0.19368  904 THR A CB  
1740 O OG1 . THR A 286 ? 1.12513 0.98716 1.22793 0.22462  -0.37001 0.21134  904 THR A OG1 
1741 C CG2 . THR A 286 ? 1.12878 0.95514 1.15260 0.20268  -0.30248 0.23512  904 THR A CG2 
1742 N N   . PHE A 287 ? 0.91118 0.75656 0.98367 0.15664  -0.25703 0.11805  905 PHE A N   
1743 C CA  . PHE A 287 ? 0.87579 0.71168 0.91870 0.13882  -0.22185 0.10421  905 PHE A CA  
1744 C C   . PHE A 287 ? 0.84630 0.67252 0.94810 0.12729  -0.19417 0.08431  905 PHE A C   
1745 O O   . PHE A 287 ? 0.82053 0.62991 0.91285 0.11776  -0.16788 0.08647  905 PHE A O   
1746 C CB  . PHE A 287 ? 0.86246 0.71544 0.86726 0.13346  -0.22664 0.07881  905 PHE A CB  
1747 C CG  . PHE A 287 ? 0.83628 0.68215 0.82825 0.11603  -0.19285 0.06211  905 PHE A CG  
1748 C CD1 . PHE A 287 ? 0.86081 0.69710 0.79637 0.11078  -0.17551 0.07503  905 PHE A CD1 
1749 C CD2 . PHE A 287 ? 0.81913 0.66894 0.85811 0.10626  -0.17741 0.03649  905 PHE A CD2 
1750 C CE1 . PHE A 287 ? 0.85521 0.68656 0.78277 0.09650  -0.14897 0.06103  905 PHE A CE1 
1751 C CE2 . PHE A 287 ? 0.85469 0.69854 0.87699 0.09297  -0.14875 0.02583  905 PHE A CE2 
1752 C CZ  . PHE A 287 ? 0.84962 0.68451 0.81690 0.08830  -0.13734 0.03727  905 PHE A CZ  
1753 N N   . TYR A 288 ? 0.86810 0.70671 1.03142 0.12878  -0.19940 0.06286  906 TYR A N   
1754 C CA  . TYR A 288 ? 0.82638 0.65884 1.03837 0.12054  -0.16921 0.04253  906 TYR A CA  
1755 C C   . TYR A 288 ? 0.84468 0.65560 1.08384 0.12349  -0.15745 0.05410  906 TYR A C   
1756 O O   . TYR A 288 ? 0.82224 0.62089 1.06121 0.11479  -0.12943 0.04022  906 TYR A O   
1757 C CB  . TYR A 288 ? 0.77517 0.62635 1.05900 0.12435  -0.17510 0.02275  906 TYR A CB  
1758 C CG  . TYR A 288 ? 0.78399 0.65414 1.06360 0.11757  -0.17757 0.00378  906 TYR A CG  
1759 C CD1 . TYR A 288 ? 0.76003 0.62650 0.99644 0.10462  -0.15211 -0.00542 906 TYR A CD1 
1760 C CD2 . TYR A 288 ? 0.80006 0.69189 1.12794 0.12463  -0.20753 -0.00541 906 TYR A CD2 
1761 C CE1 . TYR A 288 ? 0.79474 0.67592 1.03902 0.09859  -0.15316 -0.02116 906 TYR A CE1 
1762 C CE2 . TYR A 288 ? 0.78224 0.68998 1.12082 0.11762  -0.21032 -0.02544 906 TYR A CE2 
1763 C CZ  . TYR A 288 ? 0.80360 0.70466 1.10168 0.10443  -0.18150 -0.03226 906 TYR A CZ  
1764 O OH  . TYR A 288 ? 0.84804 0.76257 1.16758 0.09767  -0.18356 -0.05061 906 TYR A OH  
1765 N N   . ASN A 289 ? 0.80703 0.61295 1.07154 0.13681  -0.18038 0.07898  907 ASN A N   
1766 C CA  . ASN A 289 ? 0.83222 0.61559 1.13950 0.14024  -0.17005 0.08964  907 ASN A CA  
1767 C C   . ASN A 289 ? 0.80810 0.57101 1.07076 0.13176  -0.15490 0.10510  907 ASN A C   
1768 O O   . ASN A 289 ? 0.79539 0.53947 1.08991 0.12690  -0.13595 0.09584  907 ASN A O   
1769 C CB  . ASN A 289 ? 0.84605 0.62911 1.19875 0.15825  -0.19964 0.11778  907 ASN A CB  
1770 C CG  . ASN A 289 ? 0.86623 0.66421 1.29953 0.16631  -0.20763 0.09780  907 ASN A CG  
1771 O OD1 . ASN A 289 ? 0.88689 0.69082 1.34870 0.15828  -0.18255 0.06393  907 ASN A OD1 
1772 N ND2 . ASN A 289 ? 0.80897 0.61431 1.28128 0.18354  -0.24146 0.12048  907 ASN A ND2 
1773 N N   . LYS A 290 ? 0.82467 0.59192 1.01898 0.13049  -0.16289 0.12611  908 LYS A N   
1774 C CA  . LYS A 290 ? 0.88921 0.64032 1.04864 0.12169  -0.14578 0.14147  908 LYS A CA  
1775 C C   . LYS A 290 ? 0.85573 0.60388 1.00771 0.10578  -0.12063 0.10793  908 LYS A C   
1776 O O   . LYS A 290 ? 0.84830 0.57899 1.01860 0.09874  -0.10588 0.10549  908 LYS A O   
1777 C CB  . LYS A 290 ? 0.95227 0.71316 1.03754 0.12486  -0.15497 0.16647  908 LYS A CB  
1778 C CG  . LYS A 290 ? 1.04482 0.80221 1.12078 0.14165  -0.17376 0.21185  908 LYS A CG  
1779 C CD  . LYS A 290 ? 1.14258 0.91715 1.13529 0.14918  -0.18619 0.22655  908 LYS A CD  
1780 C CE  . LYS A 290 ? 1.25720 1.02554 1.22248 0.16610  -0.19520 0.28007  908 LYS A CE  
1781 N NZ  . LYS A 290 ? 1.32183 1.06796 1.29474 0.15834  -0.16425 0.31003  908 LYS A NZ  
1782 N N   . ILE A 291 ? 0.85987 0.62541 0.98818 0.10079  -0.11718 0.08228  909 ILE A N   
1783 C CA  . ILE A 291 ? 0.83694 0.60206 0.95067 0.08861  -0.09508 0.05460  909 ILE A CA  
1784 C C   . ILE A 291 ? 0.86967 0.62339 1.03321 0.08876  -0.08137 0.03195  909 ILE A C   
1785 O O   . ILE A 291 ? 0.88384 0.62630 1.04307 0.08166  -0.06887 0.01892  909 ILE A O   
1786 C CB  . ILE A 291 ? 0.83144 0.61639 0.92206 0.08550  -0.09282 0.03703  909 ILE A CB  
1787 C CG1 . ILE A 291 ? 0.91786 0.71325 0.95862 0.08552  -0.10610 0.05130  909 ILE A CG1 
1788 C CG2 . ILE A 291 ? 0.81566 0.60028 0.89053 0.07612  -0.06980 0.01405  909 ILE A CG2 
1789 C CD1 . ILE A 291 ? 0.93036 0.71944 0.92424 0.07726  -0.09527 0.06001  909 ILE A CD1 
1790 N N   . LYS A 292 ? 0.82629 0.58414 1.04098 0.09788  -0.08454 0.02371  910 LYS A N   
1791 C CA  . LYS A 292 ? 0.81840 0.56568 1.08276 0.10056  -0.06924 -0.00118 910 LYS A CA  
1792 C C   . LYS A 292 ? 0.85042 0.57323 1.14625 0.10091  -0.07193 0.00770  910 LYS A C   
1793 O O   . LYS A 292 ? 0.87075 0.58179 1.18952 0.09891  -0.05826 -0.02036 910 LYS A O   
1794 C CB  . LYS A 292 ? 0.79369 0.55056 1.11954 0.11187  -0.07172 -0.00816 910 LYS A CB  
1795 C CG  . LYS A 292 ? 0.82076 0.60204 1.13941 0.11150  -0.06861 -0.01665 910 LYS A CG  
1796 C CD  . LYS A 292 ? 0.83586 0.62704 1.23114 0.12192  -0.06488 -0.02868 910 LYS A CD  
1797 C CE  . LYS A 292 ? 0.84251 0.65568 1.25876 0.12599  -0.08755 -0.01736 910 LYS A CE  
1798 N NZ  . LYS A 292 ? 0.86118 0.68731 1.36450 0.13564  -0.08325 -0.02981 910 LYS A NZ  
1799 N N   . SER A 293 ? 0.85353 0.56848 1.15220 0.10428  -0.08872 0.04593  911 SER A N   
1800 C CA  . SER A 293 ? 0.82137 0.51154 1.16283 0.10464  -0.08926 0.06208  911 SER A CA  
1801 C C   . SER A 293 ? 0.82127 0.50281 1.13072 0.09159  -0.08079 0.06505  911 SER A C   
1802 O O   . SER A 293 ? 0.88812 0.54947 1.23766 0.08998  -0.08009 0.08336  911 SER A O   
1803 C CB  . SER A 293 ? 0.88514 0.57044 1.24732 0.11673  -0.10836 0.10959  911 SER A CB  
1804 O OG  . SER A 293 ? 0.94023 0.63311 1.34875 0.13002  -0.12035 0.10671  911 SER A OG  
1805 N N   . GLY A 294 ? 0.82765 0.52407 1.07531 0.08260  -0.07435 0.04990  912 GLY A N   
1806 C CA  . GLY A 294 ? 0.86385 0.55560 1.08843 0.07062  -0.06754 0.04847  912 GLY A CA  
1807 C C   . GLY A 294 ? 0.88598 0.58311 1.06816 0.06789  -0.06949 0.08620  912 GLY A C   
1808 O O   . GLY A 294 ? 0.92930 0.62119 1.10976 0.05850  -0.06245 0.09099  912 GLY A O   
1809 N N   . TYR A 295 ? 0.83801 0.54690 0.98798 0.07664  -0.07900 0.11065  913 TYR A N   
1810 C CA  . TYR A 295 ? 0.84036 0.55631 0.94001 0.07648  -0.07837 0.14218  913 TYR A CA  
1811 C C   . TYR A 295 ? 0.82221 0.55226 0.87308 0.06637  -0.07001 0.12169  913 TYR A C   
1812 O O   . TYR A 295 ? 0.85493 0.59706 0.88891 0.06503  -0.07154 0.09389  913 TYR A O   
1813 C CB  . TYR A 295 ? 0.87033 0.59810 0.93985 0.09069  -0.09521 0.16582  913 TYR A CB  
1814 C CG  . TYR A 295 ? 0.93529 0.67220 0.94196 0.09332  -0.09275 0.19367  913 TYR A CG  
1815 C CD1 . TYR A 295 ? 0.94948 0.67619 0.95452 0.10007  -0.08744 0.23876  913 TYR A CD1 
1816 C CD2 . TYR A 295 ? 0.89974 0.65502 0.85134 0.08997  -0.09245 0.17541  913 TYR A CD2 
1817 C CE1 . TYR A 295 ? 0.99143 0.72807 0.93350 0.10450  -0.07990 0.26375  913 TYR A CE1 
1818 C CE2 . TYR A 295 ? 0.91816 0.68227 0.81255 0.09384  -0.08765 0.19558  913 TYR A CE2 
1819 C CZ  . TYR A 295 ? 1.01202 0.76781 0.89766 0.10161  -0.08032 0.23911  913 TYR A CZ  
1820 O OH  . TYR A 295 ? 1.07439 0.84067 0.89729 0.10761  -0.07076 0.25898  913 TYR A OH  
1821 N N   . ARG A 296 ? 0.81651 0.54518 0.85122 0.05992  -0.05929 0.13831  914 ARG A N   
1822 C CA  . ARG A 296 ? 0.83824 0.58034 0.83236 0.05187  -0.05183 0.12404  914 ARG A CA  
1823 C C   . ARG A 296 ? 0.85480 0.60297 0.81238 0.05428  -0.04319 0.15526  914 ARG A C   
1824 O O   . ARG A 296 ? 0.87480 0.61349 0.84651 0.05859  -0.03702 0.18965  914 ARG A O   
1825 C CB  . ARG A 296 ? 0.76396 0.50053 0.78708 0.03997  -0.04518 0.10107  914 ARG A CB  
1826 C CG  . ARG A 296 ? 0.75727 0.48751 0.81066 0.03957  -0.05060 0.06758  914 ARG A CG  
1827 C CD  . ARG A 296 ? 0.75087 0.49555 0.76828 0.04264  -0.05229 0.04491  914 ARG A CD  
1828 N NE  . ARG A 296 ? 0.80430 0.54489 0.84311 0.04372  -0.05132 0.01307  914 ARG A NE  
1829 C CZ  . ARG A 296 ? 0.83164 0.56964 0.89415 0.05155  -0.05193 0.00455  914 ARG A CZ  
1830 N NH1 . ARG A 296 ? 0.73452 0.47427 0.80522 0.05874  -0.05861 0.02615  914 ARG A NH1 
1831 N NH2 . ARG A 296 ? 0.86479 0.60008 0.94268 0.05370  -0.04642 -0.02687 914 ARG A NH2 
1832 N N   . MET A 297 ? 0.84406 0.60784 0.75658 0.05247  -0.04010 0.14391  915 MET A N   
1833 C CA  . MET A 297 ? 0.87693 0.64927 0.74903 0.05626  -0.02870 0.16645  915 MET A CA  
1834 C C   . MET A 297 ? 0.84063 0.60577 0.74418 0.04835  -0.00859 0.18617  915 MET A C   
1835 O O   . MET A 297 ? 0.82225 0.58129 0.77140 0.03701  -0.00695 0.16985  915 MET A O   
1836 C CB  . MET A 297 ? 0.93122 0.71995 0.76336 0.05485  -0.02857 0.14311  915 MET A CB  
1837 C CG  . MET A 297 ? 0.92779 0.72655 0.73010 0.06372  -0.04639 0.12822  915 MET A CG  
1838 S SD  . MET A 297 ? 0.86272 0.67788 0.62832 0.06268  -0.04322 0.10434  915 MET A SD  
1839 C CE  . MET A 297 ? 0.73456 0.54769 0.53611 0.05048  -0.04219 0.07738  915 MET A CE  
1840 N N   . ALA A 298 ? 0.83248 0.59989 0.71228 0.05543  0.00683  0.22118  916 ALA A N   
1841 C CA  . ALA A 298 ? 0.84451 0.60869 0.75831 0.04807  0.03166  0.24309  916 ALA A CA  
1842 C C   . ALA A 298 ? 0.85438 0.63376 0.75671 0.04063  0.04196  0.22196  916 ALA A C   
1843 O O   . ALA A 298 ? 0.83288 0.62374 0.69575 0.04258  0.03171  0.19508  916 ALA A O   
1844 C CB  . ALA A 298 ? 0.88824 0.65117 0.77693 0.06019  0.05093  0.29247  916 ALA A CB  
1845 N N   . LYS A 299 ? 0.92007 0.69939 0.86737 0.03218  0.06269  0.23559  917 LYS A N   
1846 C CA  . LYS A 299 ? 0.88540 0.67915 0.83949 0.02490  0.07119  0.21670  917 LYS A CA  
1847 C C   . LYS A 299 ? 0.84761 0.65721 0.73671 0.03566  0.08762  0.22301  917 LYS A C   
1848 O O   . LYS A 299 ? 0.87694 0.68807 0.73865 0.04549  0.10924  0.25634  917 LYS A O   
1849 C CB  . LYS A 299 ? 0.91552 0.70706 0.94803 0.01343  0.08852  0.23042  917 LYS A CB  
1850 C CG  . LYS A 299 ? 0.94734 0.75587 0.99882 0.00697  0.09704  0.21459  917 LYS A CG  
1851 C CD  . LYS A 299 ? 0.99923 0.80768 1.14094 -0.00423 0.11375  0.22977  917 LYS A CD  
1852 C CE  . LYS A 299 ? 1.09719 0.90600 1.24193 0.00165  0.15392  0.27770  917 LYS A CE  
1853 N NZ  . LYS A 299 ? 1.13375 0.96123 1.21812 0.01203  0.17880  0.28379  917 LYS A NZ  
1854 N N   . PRO A 300 ? 0.84263 0.66397 0.70630 0.03544  0.07937  0.19220  918 PRO A N   
1855 C CA  . PRO A 300 ? 0.85549 0.69161 0.66737 0.04551  0.09604  0.19122  918 PRO A CA  
1856 C C   . PRO A 300 ? 0.87601 0.72057 0.71601 0.04389  0.13113  0.21298  918 PRO A C   
1857 O O   . PRO A 300 ? 0.83646 0.67821 0.74744 0.03193  0.13767  0.22040  918 PRO A O   
1858 C CB  . PRO A 300 ? 0.83083 0.67395 0.63811 0.04222  0.07944  0.15333  918 PRO A CB  
1859 C CG  . PRO A 300 ? 0.81611 0.64870 0.65036 0.03419  0.05337  0.13837  918 PRO A CG  
1860 C CD  . PRO A 300 ? 0.84095 0.66203 0.72262 0.02743  0.05586  0.15778  918 PRO A CD  
1861 N N   . ASP A 301 ? 1.02582 0.88234 0.81176 0.05695  0.15404  0.22069  919 ASP A N   
1862 C CA  . ASP A 301 ? 1.12690 0.99342 0.93368 0.05857  0.19554  0.24576  919 ASP A CA  
1863 C C   . ASP A 301 ? 1.05962 0.93403 0.94362 0.04499  0.20141  0.23001  919 ASP A C   
1864 O O   . ASP A 301 ? 1.07236 0.94852 1.02416 0.03702  0.22378  0.25251  919 ASP A O   
1865 C CB  . ASP A 301 ? 1.29343 1.17428 1.01953 0.07715  0.21754  0.24451  919 ASP A CB  
1866 C CG  . ASP A 301 ? 1.49925 1.37640 1.15061 0.09384  0.21925  0.27283  919 ASP A CG  
1867 O OD1 . ASP A 301 ? 1.58547 1.44754 1.25492 0.09047  0.20418  0.29600  919 ASP A OD1 
1868 O OD2 . ASP A 301 ? 1.61713 1.50698 1.19124 0.11194  0.23461  0.27095  919 ASP A OD2 
1869 N N   . HIS A 302 ? 0.97268 0.85237 0.85420 0.04269  0.18056  0.19314  920 HIS A N   
1870 C CA  . HIS A 302 ? 0.91521 0.80562 0.86129 0.03414  0.18413  0.17862  920 HIS A CA  
1871 C C   . HIS A 302 ? 0.86020 0.74352 0.86092 0.02049  0.15011  0.16379  920 HIS A C   
1872 O O   . HIS A 302 ? 0.85583 0.74819 0.89774 0.01575  0.14069  0.14663  920 HIS A O   
1873 C CB  . HIS A 302 ? 0.86794 0.76934 0.78178 0.04274  0.18639  0.15109  920 HIS A CB  
1874 C CG  . HIS A 302 ? 0.97099 0.88131 0.82427 0.05853  0.21828  0.15685  920 HIS A CG  
1875 N ND1 . HIS A 302 ? 1.02304 0.94757 0.89832 0.06318  0.26075  0.17181  920 HIS A ND1 
1876 C CD2 . HIS A 302 ? 1.02864 0.93742 0.79845 0.07228  0.21356  0.14813  920 HIS A CD2 
1877 C CE1 . HIS A 302 ? 1.07205 1.00304 0.87064 0.08035  0.28295  0.17175  920 HIS A CE1 
1878 N NE2 . HIS A 302 ? 1.08536 1.00722 0.81827 0.08626  0.25187  0.15611  920 HIS A NE2 
1879 N N   . ALA A 303 ? 0.80647 0.67458 0.80695 0.01597  0.13101  0.16935  921 ALA A N   
1880 C CA  . ALA A 303 ? 0.78331 0.64531 0.83363 0.00469  0.10178  0.15391  921 ALA A CA  
1881 C C   . ALA A 303 ? 0.82924 0.69162 0.96349 -0.00551 0.11221  0.16986  921 ALA A C   
1882 O O   . ALA A 303 ? 0.89634 0.75340 1.04407 -0.00478 0.13748  0.20010  921 ALA A O   
1883 C CB  . ALA A 303 ? 0.70918 0.55493 0.72602 0.00553  0.07755  0.14658  921 ALA A CB  
1884 N N   . THR A 304 ? 0.80957 0.67911 1.00359 -0.01419 0.09212  0.15062  922 THR A N   
1885 C CA  . THR A 304 ? 0.75936 0.62753 1.04450 -0.02567 0.08989  0.15577  922 THR A CA  
1886 C C   . THR A 304 ? 0.78622 0.63500 1.07444 -0.02983 0.06447  0.14514  922 THR A C   
1887 O O   . THR A 304 ? 0.76260 0.60216 0.98526 -0.02396 0.04744  0.13194  922 THR A O   
1888 C CB  . THR A 304 ? 0.74421 0.62990 1.09391 -0.03175 0.07094  0.13458  922 THR A CB  
1889 O OG1 . THR A 304 ? 0.70507 0.59041 1.01351 -0.02880 0.03283  0.10443  922 THR A OG1 
1890 C CG2 . THR A 304 ? 0.71067 0.61561 1.07040 -0.02698 0.09872  0.14479  922 THR A CG2 
1891 N N   . SER A 305 ? 0.82809 0.67066 1.20198 -0.03995 0.06384  0.15005  923 SER A N   
1892 C CA  . SER A 305 ? 0.82306 0.64685 1.21329 -0.04378 0.03905  0.13372  923 SER A CA  
1893 C C   . SER A 305 ? 0.79110 0.61890 1.15287 -0.04258 -0.00172 0.09000  923 SER A C   
1894 O O   . SER A 305 ? 0.82120 0.63624 1.13672 -0.03803 -0.01734 0.07478  923 SER A O   
1895 C CB  . SER A 305 ? 0.82682 0.64396 1.33145 -0.05593 0.04328  0.14091  923 SER A CB  
1896 O OG  . SER A 305 ? 0.92328 0.74243 1.46300 -0.05688 0.08687  0.18599  923 SER A OG  
1897 N N   . GLU A 306 ? 0.73361 0.58051 1.12104 -0.04483 -0.01781 0.07177  924 GLU A N   
1898 C CA  . GLU A 306 ? 0.80593 0.65911 1.15853 -0.04080 -0.05564 0.03557  924 GLU A CA  
1899 C C   . GLU A 306 ? 0.78514 0.63477 1.03598 -0.02987 -0.05371 0.03597  924 GLU A C   
1900 O O   . GLU A 306 ? 0.76690 0.61051 0.97575 -0.02531 -0.07474 0.01353  924 GLU A O   
1901 C CB  . GLU A 306 ? 0.88873 0.76534 1.28356 -0.04226 -0.07194 0.02451  924 GLU A CB  
1902 C CG  . GLU A 306 ? 1.00874 0.89256 1.51725 -0.05356 -0.08457 0.01398  924 GLU A CG  
1903 C CD  . GLU A 306 ? 1.10692 0.99387 1.68730 -0.06096 -0.04400 0.04898  924 GLU A CD  
1904 O OE1 . GLU A 306 ? 1.16644 1.05421 1.69863 -0.05511 -0.00852 0.07825  924 GLU A OE1 
1905 O OE2 . GLU A 306 ? 1.23419 1.12341 1.92096 -0.07197 -0.04658 0.04629  924 GLU A OE2 
1906 N N   . VAL A 307 ? 0.78766 0.64173 1.00195 -0.02509 -0.02740 0.05944  925 VAL A N   
1907 C CA  . VAL A 307 ? 0.78218 0.63362 0.91439 -0.01579 -0.02596 0.05828  925 VAL A CA  
1908 C C   . VAL A 307 ? 0.77272 0.60630 0.86983 -0.01318 -0.02190 0.06220  925 VAL A C   
1909 O O   . VAL A 307 ? 0.75456 0.58371 0.80210 -0.00755 -0.03221 0.04982  925 VAL A O   
1910 C CB  . VAL A 307 ? 0.74554 0.60705 0.85701 -0.01098 -0.00152 0.07540  925 VAL A CB  
1911 C CG1 . VAL A 307 ? 0.78916 0.64639 0.82860 -0.00247 -0.00055 0.07214  925 VAL A CG1 
1912 C CG2 . VAL A 307 ? 0.71014 0.58975 0.86126 -0.01186 -0.00788 0.06977  925 VAL A CG2 
1913 N N   . TYR A 308 ? 0.75786 0.58138 0.88572 -0.01645 -0.00580 0.08211  926 TYR A N   
1914 C CA  . TYR A 308 ? 0.75716 0.56384 0.86098 -0.01265 -0.00515 0.08786  926 TYR A CA  
1915 C C   . TYR A 308 ? 0.79984 0.59690 0.91973 -0.01466 -0.02957 0.05903  926 TYR A C   
1916 O O   . TYR A 308 ? 0.79009 0.57993 0.87023 -0.00860 -0.03608 0.04936  926 TYR A O   
1917 C CB  . TYR A 308 ? 0.80840 0.60558 0.94537 -0.01400 0.01745  0.12127  926 TYR A CB  
1918 C CG  . TYR A 308 ? 0.82715 0.60886 0.93464 -0.00689 0.01745  0.13319  926 TYR A CG  
1919 C CD1 . TYR A 308 ? 0.79262 0.57752 0.82945 0.00291  0.01460  0.13149  926 TYR A CD1 
1920 C CD2 . TYR A 308 ? 0.83754 0.60172 0.99744 -0.00964 0.01863  0.14563  926 TYR A CD2 
1921 C CE1 . TYR A 308 ? 0.82195 0.59555 0.83883 0.01040  0.01080  0.14176  926 TYR A CE1 
1922 C CE2 . TYR A 308 ? 0.83814 0.58887 0.97702 -0.00149 0.01671  0.15854  926 TYR A CE2 
1923 C CZ  . TYR A 308 ? 0.83968 0.59647 0.90596 0.00882  0.01169  0.15645  926 TYR A CZ  
1924 O OH  . TYR A 308 ? 0.88711 0.63308 0.94009 0.01777  0.00614  0.16878  926 TYR A OH  
1925 N N   . GLU A 309 ? 0.80415 0.60248 0.98571 -0.02240 -0.04338 0.04213  927 GLU A N   
1926 C CA  . GLU A 309 ? 0.79789 0.58898 0.99191 -0.02262 -0.06841 0.00688  927 GLU A CA  
1927 C C   . GLU A 309 ? 0.77449 0.57343 0.89666 -0.01393 -0.08181 -0.01473 927 GLU A C   
1928 O O   . GLU A 309 ? 0.72892 0.51926 0.82811 -0.00879 -0.08939 -0.03437 927 GLU A O   
1929 C CB  . GLU A 309 ? 0.75746 0.55426 1.02678 -0.03131 -0.08703 -0.01420 927 GLU A CB  
1930 N N   . ILE A 310 ? 0.73166 0.54671 0.82225 -0.01140 -0.08169 -0.00919 928 ILE A N   
1931 C CA  . ILE A 310 ? 0.75571 0.57774 0.78219 -0.00263 -0.08979 -0.02122 928 ILE A CA  
1932 C C   . ILE A 310 ? 0.77167 0.58449 0.75375 0.00304  -0.07457 -0.01183 928 ILE A C   
1933 O O   . ILE A 310 ? 0.82354 0.63406 0.77184 0.00936  -0.07913 -0.02749 928 ILE A O   
1934 C CB  . ILE A 310 ? 0.70935 0.54813 0.72367 -0.00085 -0.09004 -0.01086 928 ILE A CB  
1935 C CG1 . ILE A 310 ? 0.70876 0.56022 0.76992 -0.00448 -0.11218 -0.02452 928 ILE A CG1 
1936 C CG2 . ILE A 310 ? 0.73857 0.58167 0.69116 0.00855  -0.09171 -0.01323 928 ILE A CG2 
1937 C CD1 . ILE A 310 ? 0.75135 0.61939 0.81911 -0.00281 -0.11090 -0.01070 928 ILE A CD1 
1938 N N   . MET A 311 ? 0.75868 0.56800 0.74076 0.00207  -0.05630 0.01313  929 MET A N   
1939 C CA  . MET A 311 ? 0.76317 0.56615 0.71110 0.00787  -0.04716 0.02051  929 MET A CA  
1940 C C   . MET A 311 ? 0.81059 0.59995 0.77272 0.00958  -0.05196 0.00910  929 MET A C   
1941 O O   . MET A 311 ? 0.77979 0.56770 0.71658 0.01553  -0.05201 -0.00096 929 MET A O   
1942 C CB  . MET A 311 ? 0.78369 0.58645 0.72777 0.00853  -0.03161 0.04666  929 MET A CB  
1943 C CG  . MET A 311 ? 0.81229 0.62773 0.74964 0.00780  -0.02216 0.05634  929 MET A CG  
1944 S SD  . MET A 311 ? 0.82364 0.63893 0.74049 0.01285  -0.00287 0.08220  929 MET A SD  
1945 C CE  . MET A 311 ? 0.75000 0.58045 0.67419 0.01166  0.01230  0.08769  929 MET A CE  
1946 N N   . VAL A 312 ? 0.82073 0.59974 0.83227 0.00458  -0.05382 0.01119  930 VAL A N   
1947 C CA  . VAL A 312 ? 0.85114 0.61469 0.88908 0.00662  -0.05753 0.00070  930 VAL A CA  
1948 C C   . VAL A 312 ? 0.88260 0.64750 0.90648 0.01048  -0.06956 -0.03634 930 VAL A C   
1949 O O   . VAL A 312 ? 0.98051 0.73878 0.99709 0.01690  -0.06732 -0.04787 930 VAL A O   
1950 C CB  . VAL A 312 ? 0.80617 0.55711 0.91304 -0.00042 -0.05660 0.01055  930 VAL A CB  
1951 C CG1 . VAL A 312 ? 0.81576 0.54913 0.96214 0.00174  -0.06308 -0.00750 930 VAL A CG1 
1952 C CG2 . VAL A 312 ? 0.75806 0.50700 0.86795 -0.00034 -0.03892 0.05306  930 VAL A CG2 
1953 N N   . LYS A 313 ? 0.85950 0.63472 0.87815 0.00837  -0.08227 -0.05539 931 LYS A N   
1954 C CA  . LYS A 313 ? 0.84889 0.62888 0.83591 0.01548  -0.09331 -0.08915 931 LYS A CA  
1955 C C   . LYS A 313 ? 0.79512 0.58145 0.72370 0.02424  -0.08017 -0.08315 931 LYS A C   
1956 O O   . LYS A 313 ? 0.75285 0.53732 0.66162 0.03216  -0.07694 -0.10383 931 LYS A O   
1957 C CB  . LYS A 313 ? 0.90719 0.70115 0.88934 0.01421  -0.11286 -0.10479 931 LYS A CB  
1958 C CG  . LYS A 313 ? 0.96442 0.75445 1.01557 0.00584  -0.13054 -0.12180 931 LYS A CG  
1959 C CD  . LYS A 313 ? 0.99856 0.80672 1.04206 0.00695  -0.15550 -0.13990 931 LYS A CD  
1960 C CE  . LYS A 313 ? 1.05013 0.85646 1.17184 -0.00114 -0.17869 -0.16629 931 LYS A CE  
1961 N NZ  . LYS A 313 ? 1.13333 0.96036 1.24876 0.00194  -0.21020 -0.18819 931 LYS A NZ  
1962 N N   . CYS A 314 ? 0.77687 0.57096 0.68339 0.02322  -0.07059 -0.05646 932 CYS A N   
1963 C CA  . CYS A 314 ? 0.79446 0.59426 0.66067 0.02998  -0.05773 -0.04976 932 CYS A CA  
1964 C C   . CYS A 314 ? 0.82947 0.62054 0.70905 0.03300  -0.04725 -0.04766 932 CYS A C   
1965 O O   . CYS A 314 ? 0.86558 0.66067 0.72573 0.03926  -0.03621 -0.05049 932 CYS A O   
1966 C CB  . CYS A 314 ? 0.77193 0.58039 0.62452 0.02770  -0.05199 -0.02612 932 CYS A CB  
1967 S SG  . CYS A 314 ? 0.79871 0.62038 0.63734 0.02742  -0.06326 -0.02521 932 CYS A SG  
1968 N N   . TRP A 315 ? 0.78947 0.56939 0.70725 0.02943  -0.04979 -0.03983 933 TRP A N   
1969 C CA  . TRP A 315 ? 0.80650 0.57898 0.74296 0.03367  -0.04437 -0.03360 933 TRP A CA  
1970 C C   . TRP A 315 ? 0.81135 0.57194 0.78062 0.03727  -0.04619 -0.05604 933 TRP A C   
1971 O O   . TRP A 315 ? 0.79849 0.54879 0.80319 0.03971  -0.04604 -0.04749 933 TRP A O   
1972 C CB  . TRP A 315 ? 0.81272 0.58067 0.76565 0.03105  -0.04569 -0.00510 933 TRP A CB  
1973 C CG  . TRP A 315 ? 0.77035 0.54963 0.69240 0.02955  -0.04259 0.01188  933 TRP A CG  
1974 C CD1 . TRP A 315 ? 0.79366 0.58432 0.68640 0.03114  -0.03859 0.00773  933 TRP A CD1 
1975 C CD2 . TRP A 315 ? 0.78553 0.56537 0.70673 0.02711  -0.04071 0.03508  933 TRP A CD2 
1976 N NE1 . TRP A 315 ? 0.80529 0.60268 0.68256 0.02958  -0.03692 0.02241  933 TRP A NE1 
1977 C CE2 . TRP A 315 ? 0.79242 0.58448 0.68166 0.02781  -0.03718 0.03849  933 TRP A CE2 
1978 C CE3 . TRP A 315 ? 0.77688 0.54783 0.72371 0.02526  -0.03865 0.05476  933 TRP A CE3 
1979 C CZ2 . TRP A 315 ? 0.79237 0.58926 0.66850 0.02777  -0.03189 0.05576  933 TRP A CZ2 
1980 C CZ3 . TRP A 315 ? 0.81871 0.59529 0.74935 0.02533  -0.03059 0.07764  933 TRP A CZ3 
1981 C CH2 . TRP A 315 ? 0.82214 0.61218 0.71474 0.02710  -0.02742 0.07554  933 TRP A CH2 
1982 N N   . ASN A 316 ? 0.81052 0.57244 0.76945 0.03916  -0.04946 -0.08569 934 ASN A N   
1983 C CA  . ASN A 316 ? 0.85901 0.61002 0.84814 0.04436  -0.04989 -0.11476 934 ASN A CA  
1984 C C   . ASN A 316 ? 0.88725 0.64084 0.87252 0.05365  -0.03400 -0.11769 934 ASN A C   
1985 O O   . ASN A 316 ? 0.86718 0.63427 0.81181 0.05772  -0.02203 -0.11420 934 ASN A O   
1986 C CB  . ASN A 316 ? 0.84625 0.60143 0.81383 0.04698  -0.05906 -0.15160 934 ASN A CB  
1987 C CG  . ASN A 316 ? 0.94927 0.69013 0.96183 0.05048  -0.06467 -0.18806 934 ASN A CG  
1988 O OD1 . ASN A 316 ? 1.00985 0.74682 1.02917 0.05950  -0.05183 -0.20394 934 ASN A OD1 
1989 N ND2 . ASN A 316 ? 0.96829 0.70156 1.02051 0.04339  -0.08331 -0.20347 934 ASN A ND2 
1990 N N   . SER A 317 ? 0.93405 0.67470 0.97111 0.05718  -0.03290 -0.12173 935 SER A N   
1991 C CA  . SER A 317 ? 0.93197 0.67638 0.98099 0.06639  -0.01835 -0.12492 935 SER A CA  
1992 C C   . SER A 317 ? 1.00782 0.76145 1.02343 0.07518  -0.00168 -0.15724 935 SER A C   
1993 O O   . SER A 317 ? 1.08992 0.85435 1.09867 0.08170  0.01706  -0.15433 935 SER A O   
1994 C CB  . SER A 317 ? 0.85739 0.58543 0.97589 0.07021  -0.02234 -0.12490 935 SER A CB  
1995 O OG  . SER A 317 ? 0.91770 0.63125 1.06682 0.07058  -0.02713 -0.15620 935 SER A OG  
1996 N N   . GLU A 318 ? 0.98397 0.73502 0.97903 0.07639  -0.00796 -0.18807 936 GLU A N   
1997 C CA  . GLU A 318 ? 1.02389 0.78560 0.96975 0.08760  0.00710  -0.21884 936 GLU A CA  
1998 C C   . GLU A 318 ? 1.01912 0.79668 0.89444 0.08646  0.00689  -0.20404 936 GLU A C   
1999 O O   . GLU A 318 ? 1.03439 0.81181 0.89542 0.07979  -0.01479 -0.20386 936 GLU A O   
2000 C CB  . GLU A 318 ? 1.03868 0.79084 0.99541 0.09236  -0.00398 -0.26571 936 GLU A CB  
2001 N N   . PRO A 319 ? 1.01011 0.80146 0.84909 0.09301  0.03097  -0.18984 937 PRO A N   
2002 C CA  . PRO A 319 ? 0.98205 0.78629 0.76423 0.09193  0.03127  -0.16757 937 PRO A CA  
2003 C C   . PRO A 319 ? 1.01618 0.82634 0.74050 0.09829  0.01703  -0.18981 937 PRO A C   
2004 O O   . PRO A 319 ? 1.00592 0.82138 0.70680 0.09314  0.00008  -0.17349 937 PRO A O   
2005 C CB  . PRO A 319 ? 0.96885 0.78449 0.73733 0.09984  0.06547  -0.15204 937 PRO A CB  
2006 C CG  . PRO A 319 ? 0.97970 0.78917 0.81478 0.09951  0.07576  -0.15553 937 PRO A CG  
2007 C CD  . PRO A 319 ? 0.98972 0.78526 0.85252 0.10076  0.05975  -0.18839 937 PRO A CD  
2008 N N   . GLU A 320 ? 1.00838 0.81899 0.71041 0.11070  0.02156  -0.22924 938 GLU A N   
2009 C CA  . GLU A 320 ? 1.08812 0.90754 0.72675 0.12005  0.00396  -0.25524 938 GLU A CA  
2010 C C   . GLU A 320 ? 1.11321 0.92647 0.78097 0.10890  -0.03666 -0.26805 938 GLU A C   
2011 O O   . GLU A 320 ? 1.12900 0.95272 0.75003 0.11477  -0.05916 -0.28355 938 GLU A O   
2012 C CB  . GLU A 320 ? 1.09256 0.91364 0.70250 0.13724  0.01670  -0.30258 938 GLU A CB  
2013 N N   . LYS A 321 ? 1.09213 0.89029 0.83712 0.09400  -0.04642 -0.25932 939 LYS A N   
2014 C CA  . LYS A 321 ? 1.05669 0.84917 0.84252 0.08232  -0.07889 -0.26651 939 LYS A CA  
2015 C C   . LYS A 321 ? 0.99482 0.79273 0.78538 0.07081  -0.08535 -0.22353 939 LYS A C   
2016 O O   . LYS A 321 ? 0.95981 0.75580 0.78770 0.06099  -0.10827 -0.22471 939 LYS A O   
2017 C CB  . LYS A 321 ? 1.04587 0.81761 0.91777 0.07400  -0.08333 -0.27962 939 LYS A CB  
2018 C CG  . LYS A 321 ? 1.15756 0.92161 1.04378 0.08360  -0.08797 -0.33453 939 LYS A CG  
2019 C CD  . LYS A 321 ? 1.18904 0.92991 1.17342 0.07489  -0.09251 -0.34170 939 LYS A CD  
2020 C CE  . LYS A 321 ? 1.31237 1.04391 1.31893 0.08550  -0.09496 -0.40055 939 LYS A CE  
2021 N NZ  . LYS A 321 ? 1.37421 1.08064 1.48425 0.07908  -0.09409 -0.40244 939 LYS A NZ  
2022 N N   . ARG A 322 ? 0.91798 0.72279 0.67939 0.07190  -0.06456 -0.18786 940 ARG A N   
2023 C CA  . ARG A 322 ? 0.88935 0.70001 0.65213 0.06323  -0.06969 -0.15272 940 ARG A CA  
2024 C C   . ARG A 322 ? 0.89612 0.72228 0.60865 0.06966  -0.08543 -0.15432 940 ARG A C   
2025 O O   . ARG A 322 ? 0.95964 0.79467 0.61445 0.08368  -0.08179 -0.16847 940 ARG A O   
2026 C CB  . ARG A 322 ? 0.86470 0.67658 0.62299 0.06242  -0.04492 -0.11946 940 ARG A CB  
2027 C CG  . ARG A 322 ? 0.84060 0.64023 0.64758 0.05796  -0.03474 -0.11498 940 ARG A CG  
2028 C CD  . ARG A 322 ? 0.84212 0.64628 0.64465 0.06047  -0.01264 -0.09353 940 ARG A CD  
2029 N NE  . ARG A 322 ? 0.86188 0.65735 0.70864 0.06045  -0.00594 -0.09532 940 ARG A NE  
2030 C CZ  . ARG A 322 ? 0.88819 0.68805 0.74516 0.06519  0.01266  -0.08924 940 ARG A CZ  
2031 N NH1 . ARG A 322 ? 0.84778 0.65903 0.67537 0.06937  0.03019  -0.07949 940 ARG A NH1 
2032 N NH2 . ARG A 322 ? 0.88635 0.67960 0.78986 0.06622  0.01379  -0.09097 940 ARG A NH2 
2033 N N   . PRO A 323 ? 0.89398 0.72481 0.62699 0.06136  -0.10242 -0.13876 941 PRO A N   
2034 C CA  . PRO A 323 ? 0.89178 0.73847 0.58634 0.06851  -0.12302 -0.13993 941 PRO A CA  
2035 C C   . PRO A 323 ? 0.88007 0.73574 0.52220 0.07749  -0.10488 -0.10837 941 PRO A C   
2036 O O   . PRO A 323 ? 0.90360 0.75399 0.55746 0.07313  -0.08015 -0.08166 941 PRO A O   
2037 C CB  . PRO A 323 ? 0.86843 0.71674 0.61980 0.05561  -0.14130 -0.12974 941 PRO A CB  
2038 C CG  . PRO A 323 ? 0.83490 0.67084 0.62719 0.04442  -0.11855 -0.10534 941 PRO A CG  
2039 C CD  . PRO A 323 ? 0.82779 0.65107 0.62048 0.04684  -0.10295 -0.11891 941 PRO A CD  
2040 N N   . SER A 324 ? 0.87955 0.74920 0.46625 0.09107  -0.11919 -0.11160 942 SER A N   
2041 C CA  . SER A 324 ? 0.95284 0.83063 0.49440 0.10088  -0.10310 -0.07601 942 SER A CA  
2042 C C   . SER A 324 ? 0.91911 0.79801 0.50199 0.09124  -0.10699 -0.04448 942 SER A C   
2043 O O   . SER A 324 ? 0.90016 0.77934 0.53172 0.08072  -0.12743 -0.05195 942 SER A O   
2044 C CB  . SER A 324 ? 1.03848 0.93199 0.50557 0.12055  -0.12089 -0.08384 942 SER A CB  
2045 O OG  . SER A 324 ? 1.06493 0.96937 0.54622 0.12002  -0.16116 -0.09083 942 SER A OG  
2046 N N   . PHE A 325 ? 0.94611 0.70819 0.49289 -0.00331 -0.05664 -0.03339 943 PHE A N   
2047 C CA  . PHE A 325 ? 0.94605 0.68690 0.49820 0.00564  -0.05711 -0.01013 943 PHE A CA  
2048 C C   . PHE A 325 ? 0.94650 0.71804 0.51954 0.01702  -0.07820 -0.01470 943 PHE A C   
2049 O O   . PHE A 325 ? 0.90723 0.66933 0.51052 0.02497  -0.07670 -0.00603 943 PHE A O   
2050 C CB  . PHE A 325 ? 0.93038 0.64359 0.42656 0.00626  -0.05158 0.01947  943 PHE A CB  
2051 C CG  . PHE A 325 ? 0.94252 0.62684 0.42894 -0.00495 -0.02898 0.02898  943 PHE A CG  
2052 C CD1 . PHE A 325 ? 0.92596 0.58803 0.44757 -0.00708 -0.01436 0.03244  943 PHE A CD1 
2053 C CD2 . PHE A 325 ? 0.94248 0.62638 0.38466 -0.01408 -0.02237 0.03414  943 PHE A CD2 
2054 C CE1 . PHE A 325 ? 0.88662 0.52989 0.39788 -0.01741 0.00466  0.04227  943 PHE A CE1 
2055 C CE2 . PHE A 325 ? 0.91046 0.57927 0.34553 -0.02465 -0.00312 0.04292  943 PHE A CE2 
2056 C CZ  . PHE A 325 ? 0.86040 0.51065 0.32953 -0.02595 0.00952  0.04759  943 PHE A CZ  
2057 N N   . TYR A 326 ? 0.97964 0.79201 0.53754 0.01781  -0.09775 -0.02838 944 TYR A N   
2058 C CA  . TYR A 326 ? 1.04757 0.90388 0.62784 0.02835  -0.12047 -0.03478 944 TYR A CA  
2059 C C   . TYR A 326 ? 1.02464 0.90292 0.67018 0.02042  -0.11774 -0.06479 944 TYR A C   
2060 O O   . TYR A 326 ? 0.98517 0.87555 0.66833 0.02968  -0.12294 -0.06164 944 TYR A O   
2061 C CB  . TYR A 326 ? 1.13963 1.03819 0.68310 0.02779  -0.14173 -0.04352 944 TYR A CB  
2062 C CG  . TYR A 326 ? 1.21911 1.17895 0.78538 0.03653  -0.16817 -0.05389 944 TYR A CG  
2063 C CD1 . TYR A 326 ? 1.25389 1.26280 0.85199 0.02060  -0.17615 -0.09304 944 TYR A CD1 
2064 C CD2 . TYR A 326 ? 1.21842 1.18943 0.77371 0.06058  -0.18352 -0.02467 944 TYR A CD2 
2065 C CE1 . TYR A 326 ? 1.30217 1.37829 0.92184 0.02574  -0.20157 -0.10448 944 TYR A CE1 
2066 C CE2 . TYR A 326 ? 1.27810 1.31595 0.85643 0.07115  -0.20960 -0.03220 944 TYR A CE2 
2067 C CZ  . TYR A 326 ? 1.32208 1.41663 0.93307 0.05235  -0.21999 -0.07294 944 TYR A CZ  
2068 O OH  . TYR A 326 ? 1.35412 1.52553 0.98878 0.06011  -0.24703 -0.08224 944 TYR A OH  
2069 N N   . HIS A 327 ? 0.96305 0.84453 0.62241 0.00312  -0.10658 -0.09465 945 HIS A N   
2070 C CA  A HIS A 327 ? 0.96204 0.85501 0.67908 -0.00770 -0.09752 -0.12539 945 HIS A CA  
2071 C CA  B HIS A 327 ? 0.96188 0.85475 0.67883 -0.00773 -0.09746 -0.12540 945 HIS A CA  
2072 C C   . HIS A 327 ? 0.91638 0.76803 0.66646 -0.00345 -0.07926 -0.11218 945 HIS A C   
2073 O O   . HIS A 327 ? 0.90971 0.77547 0.70814 -0.00533 -0.07845 -0.12675 945 HIS A O   
2074 C CB  A HIS A 327 ? 0.97577 0.86315 0.69413 -0.02539 -0.08062 -0.15548 945 HIS A CB  
2075 C CB  B HIS A 327 ? 0.97535 0.86195 0.69331 -0.02533 -0.08034 -0.15515 945 HIS A CB  
2076 C CG  A HIS A 327 ? 0.98507 0.91938 0.68332 -0.03553 -0.09628 -0.17964 945 HIS A CG  
2077 C CG  B HIS A 327 ? 0.97692 0.87051 0.74746 -0.03946 -0.06656 -0.19027 945 HIS A CG  
2078 N ND1 A HIS A 327 ? 1.00197 0.99547 0.71207 -0.03656 -0.12145 -0.19301 945 HIS A ND1 
2079 N ND1 B HIS A 327 ? 0.99731 0.94235 0.80058 -0.04638 -0.08189 -0.21452 945 HIS A ND1 
2080 C CD2 A HIS A 327 ? 0.99396 0.92783 0.66024 -0.04561 -0.09003 -0.19287 945 HIS A CD2 
2081 C CD2 B HIS A 327 ? 0.98856 0.84436 0.78297 -0.04842 -0.03693 -0.20545 945 HIS A CD2 
2082 C CE1 A HIS A 327 ? 1.01990 1.04694 0.70351 -0.04898 -0.13049 -0.21422 945 HIS A CE1 
2083 C CE1 B HIS A 327 ? 0.99969 0.93572 0.84434 -0.06239 -0.06064 -0.24587 945 HIS A CE1 
2084 N NE2 A HIS A 327 ? 1.01267 1.00131 0.66940 -0.05493 -0.11061 -0.21507 945 HIS A NE2 
2085 N NE2 B HIS A 327 ? 0.98647 0.86455 0.82510 -0.06263 -0.03230 -0.23988 945 HIS A NE2 
2086 N N   . LEU A 328 ? 0.90143 0.70478 0.62538 0.00018  -0.06383 -0.08593 946 LEU A N   
2087 C CA  . LEU A 328 ? 0.87305 0.63665 0.62154 0.00256  -0.04639 -0.07149 946 LEU A CA  
2088 C C   . LEU A 328 ? 0.89847 0.67167 0.66420 0.01545  -0.05794 -0.05663 946 LEU A C   
2089 O O   . LEU A 328 ? 0.86177 0.62550 0.67134 0.01481  -0.04853 -0.06193 946 LEU A O   
2090 C CB  . LEU A 328 ? 0.86562 0.58608 0.57553 0.00208  -0.03079 -0.04515 946 LEU A CB  
2091 C CG  . LEU A 328 ? 0.84617 0.55195 0.55330 -0.00700 -0.01247 -0.05598 946 LEU A CG  
2092 C CD1 . LEU A 328 ? 0.86688 0.54791 0.53131 -0.00766 -0.00250 -0.02953 946 LEU A CD1 
2093 C CD2 . LEU A 328 ? 0.82119 0.50678 0.57547 -0.01150 0.00664  -0.07022 946 LEU A CD2 
2094 N N   . SER A 329 ? 0.89085 0.68191 0.62218 0.02859  -0.07661 -0.03745 947 SER A N   
2095 C CA  . SER A 329 ? 0.92473 0.72714 0.67090 0.04633  -0.08694 -0.02004 947 SER A CA  
2096 C C   . SER A 329 ? 0.85663 0.71239 0.66123 0.04661  -0.09965 -0.04689 947 SER A C   
2097 O O   . SER A 329 ? 0.85500 0.70824 0.70071 0.05316  -0.09429 -0.04379 947 SER A O   
2098 C CB  . SER A 329 ? 0.96768 0.78139 0.66168 0.06257  -0.10405 0.00493  947 SER A CB  
2099 O OG  . SER A 329 ? 1.03498 0.79637 0.67630 0.06011  -0.08839 0.02981  947 SER A OG  
2100 N N   . GLU A 330 ? 0.85781 0.76373 0.66706 0.03686  -0.11463 -0.07576 948 GLU A N   
2101 C CA  . GLU A 330 ? 0.93895 0.90406 0.80209 0.03153  -0.12624 -0.10638 948 GLU A CA  
2102 C C   . GLU A 330 ? 0.93929 0.87870 0.85433 0.01646  -0.10191 -0.12808 948 GLU A C   
2103 O O   . GLU A 330 ? 0.94649 0.91029 0.91064 0.01927  -0.10340 -0.13631 948 GLU A O   
2104 C CB  . GLU A 330 ? 1.03985 1.05724 0.89115 0.01701  -0.14161 -0.13691 948 GLU A CB  
2105 C CG  . GLU A 330 ? 1.18582 1.21445 0.97456 0.02726  -0.15999 -0.11675 948 GLU A CG  
2106 C CD  . GLU A 330 ? 1.33897 1.42116 1.12176 0.05064  -0.18902 -0.09701 948 GLU A CD  
2107 O OE1 . GLU A 330 ? 1.40988 1.54268 1.16524 0.05014  -0.21142 -0.10418 948 GLU A OE1 
2108 O OE2 . GLU A 330 ? 1.37640 1.45079 1.18106 0.07057  -0.18858 -0.07355 948 GLU A OE2 
2109 N N   . ILE A 331 ? 0.95144 0.84188 0.85578 0.00170  -0.07817 -0.13633 949 ILE A N   
2110 C CA  . ILE A 331 ? 0.90304 0.76311 0.85009 -0.01236 -0.05221 -0.15629 949 ILE A CA  
2111 C C   . ILE A 331 ? 0.90068 0.72785 0.86968 -0.00222 -0.04173 -0.13360 949 ILE A C   
2112 O O   . ILE A 331 ? 0.91085 0.74594 0.92997 -0.00803 -0.03351 -0.15083 949 ILE A O   
2113 C CB  . ILE A 331 ? 0.94680 0.75811 0.87078 -0.02330 -0.02842 -0.16062 949 ILE A CB  
2114 C CG1 . ILE A 331 ? 1.00466 0.84629 0.91850 -0.03696 -0.03180 -0.19185 949 ILE A CG1 
2115 C CG2 . ILE A 331 ? 0.96934 0.73500 0.92768 -0.03199 0.00126  -0.16915 949 ILE A CG2 
2116 C CD1 . ILE A 331 ? 1.07615 0.87266 0.96912 -0.04344 -0.00682 -0.19495 949 ILE A CD1 
2117 N N   . VAL A 332 ? 0.88299 0.67133 0.81360 0.01045  -0.03917 -0.09654 950 VAL A N   
2118 C CA  . VAL A 332 ? 0.84174 0.59403 0.78735 0.01815  -0.02620 -0.07459 950 VAL A CA  
2119 C C   . VAL A 332 ? 0.83909 0.63515 0.81844 0.03350  -0.04266 -0.07207 950 VAL A C   
2120 O O   . VAL A 332 ? 0.84151 0.62447 0.85946 0.03543  -0.03058 -0.07083 950 VAL A O   
2121 C CB  . VAL A 332 ? 0.85035 0.55394 0.74162 0.02436  -0.01807 -0.03817 950 VAL A CB  
2122 C CG1 . VAL A 332 ? 0.80806 0.47038 0.71129 0.02882  -0.00096 -0.01734 950 VAL A CG1 
2123 C CG2 . VAL A 332 ? 0.82972 0.50231 0.69298 0.01074  -0.00318 -0.04078 950 VAL A CG2 
2124 N N   . GLU A 333 ? 0.86335 0.71484 0.82951 0.04551  -0.07000 -0.07097 951 GLU A N   
2125 C CA  . GLU A 333 ? 0.92632 0.83049 0.92477 0.06466  -0.08823 -0.06582 951 GLU A CA  
2126 C C   . GLU A 333 ? 0.87249 0.81973 0.94000 0.05212  -0.08661 -0.10197 951 GLU A C   
2127 O O   . GLU A 333 ? 0.82612 0.78959 0.93601 0.06374  -0.08546 -0.09706 951 GLU A O   
2128 C CB  . GLU A 333 ? 1.02532 0.98613 0.99198 0.07869  -0.11896 -0.05905 951 GLU A CB  
2129 C CG  . GLU A 333 ? 1.13491 1.13633 1.11180 0.10979  -0.13724 -0.03407 951 GLU A CG  
2130 C CD  . GLU A 333 ? 1.24571 1.28544 1.17366 0.12615  -0.16396 -0.01787 951 GLU A CD  
2131 O OE1 . GLU A 333 ? 1.26956 1.34128 1.18002 0.10928  -0.17668 -0.04169 951 GLU A OE1 
2132 O OE2 . GLU A 333 ? 1.31483 1.34844 1.21897 0.15583  -0.16971 0.01909  951 GLU A OE2 
2133 N N   . ASN A 334 ? 0.83673 0.80094 0.91622 0.02738  -0.08337 -0.13963 952 ASN A N   
2134 C CA  . ASN A 334 ? 0.90991 0.91254 1.05140 0.00975  -0.07771 -0.17900 952 ASN A CA  
2135 C C   . ASN A 334 ? 0.88847 0.83206 1.06189 0.00102  -0.04615 -0.18109 952 ASN A C   
2136 O O   . ASN A 334 ? 0.91314 0.88489 1.14212 -0.00940 -0.03948 -0.20735 952 ASN A O   
2137 C CB  . ASN A 334 ? 1.02113 1.04698 1.15981 -0.01684 -0.07647 -0.21956 952 ASN A CB  
2138 C CG  . ASN A 334 ? 1.13524 1.23401 1.25101 -0.01298 -0.10877 -0.22554 952 ASN A CG  
2139 O OD1 . ASN A 334 ? 1.18186 1.32665 1.29374 0.01060  -0.13450 -0.20259 952 ASN A OD1 
2140 N ND2 . ASN A 334 ? 1.17284 1.28084 1.27163 -0.03548 -0.10574 -0.25577 952 ASN A ND2 
2141 N N   . LEU A 335 ? 0.89257 0.75827 1.03137 0.00332  -0.02623 -0.15503 953 LEU A N   
2142 C CA  . LEU A 335 ? 0.87451 0.68378 1.03747 -0.00318 0.00258  -0.15174 953 LEU A CA  
2143 C C   . LEU A 335 ? 0.87894 0.68718 1.06111 0.01619  0.00147  -0.12634 953 LEU A C   
2144 O O   . LEU A 335 ? 0.88822 0.66755 1.10488 0.00988  0.02289  -0.13073 953 LEU A O   
2145 C CB  . LEU A 335 ? 0.85640 0.59020 0.97400 -0.00904 0.02377  -0.13317 953 LEU A CB  
2146 C CG  . LEU A 335 ? 0.87281 0.59687 0.96936 -0.02405 0.03069  -0.15302 953 LEU A CG  
2147 C CD1 . LEU A 335 ? 0.90150 0.55562 0.96656 -0.02791 0.05507  -0.13414 953 LEU A CD1 
2148 C CD2 . LEU A 335 ? 0.79948 0.54877 0.94186 -0.04337 0.03999  -0.19744 953 LEU A CD2 
2149 N N   . LEU A 336 ? 0.84280 0.67867 1.00225 0.04014  -0.02039 -0.09971 954 LEU A N   
2150 C CA  . LEU A 336 ? 0.83805 0.66799 1.01260 0.06224  -0.01795 -0.07274 954 LEU A CA  
2151 C C   . LEU A 336 ? 0.80885 0.71671 1.04820 0.07122  -0.03245 -0.09141 954 LEU A C   
2152 O O   . LEU A 336 ? 0.76934 0.75031 1.02567 0.06661  -0.05504 -0.11666 954 LEU A O   
2153 C CB  . LEU A 336 ? 0.89185 0.71119 1.01099 0.08635  -0.03049 -0.03369 954 LEU A CB  
2154 C CG  . LEU A 336 ? 0.89477 0.63063 0.95645 0.07903  -0.00885 -0.00879 954 LEU A CG  
2155 C CD1 . LEU A 336 ? 0.90171 0.63352 0.90071 0.09438  -0.02246 0.01938  954 LEU A CD1 
2156 C CD2 . LEU A 336 ? 0.86100 0.54075 0.93515 0.08103  0.01874  0.00887  954 LEU A CD2 
2157 N N   . PRO A 337 ? 0.80897 0.70589 1.08639 0.08217  -0.01854 -0.08123 955 PRO A N   
2158 C CA  . PRO A 337 ? 0.85193 0.83095 1.19469 0.09393  -0.03260 -0.09640 955 PRO A CA  
2159 C C   . PRO A 337 ? 0.93513 0.97841 1.26549 0.12841  -0.06403 -0.07134 955 PRO A C   
2160 O O   . PRO A 337 ? 0.97126 0.97617 1.24604 0.14863  -0.06638 -0.03393 955 PRO A O   
2161 C CB  . PRO A 337 ? 0.84302 0.77741 1.22074 0.09842  -0.00428 -0.08602 955 PRO A CB  
2162 C CG  . PRO A 337 ? 0.84202 0.68271 1.15888 0.10300  0.01530  -0.04983 955 PRO A CG  
2163 C CD  . PRO A 337 ? 0.80912 0.62120 1.07291 0.08250  0.01221  -0.05714 955 PRO A CD  
2164 N N   . GLY A 338 ? 1.01704 1.16127 1.39852 0.13411  -0.08742 -0.09285 956 GLY A N   
2165 C CA  . GLY A 338 ? 1.15280 1.37295 1.52697 0.16805  -0.12032 -0.07072 956 GLY A CA  
2166 C C   . GLY A 338 ? 1.27108 1.50522 1.58401 0.16475  -0.14343 -0.06826 956 GLY A C   
2167 O O   . GLY A 338 ? 1.29283 1.45904 1.55765 0.14363  -0.13060 -0.07117 956 GLY A O   
2168 N N   . GLN A 339 ? 1.40461 1.73042 1.71886 0.18633  -0.17764 -0.06224 957 GLN A N   
2169 C CA  . GLN A 339 ? 1.54708 1.89360 1.80244 0.18490  -0.20132 -0.05906 957 GLN A CA  
2170 C C   . GLN A 339 ? 1.75663 2.14580 1.98696 0.23065  -0.22597 -0.01598 957 GLN A C   
2171 O O   . GLN A 339 ? 1.73844 2.20143 2.01701 0.25762  -0.23991 -0.00754 957 GLN A O   
2172 C CB  . GLN A 339 ? 1.52308 1.95200 1.80247 0.15219  -0.21978 -0.10988 957 GLN A CB  
2173 C CG  . GLN A 339 ? 1.48615 1.85077 1.74782 0.10996  -0.19665 -0.14264 957 GLN A CG  
2174 C CD  . GLN A 339 ? 1.45294 1.87944 1.76369 0.07302  -0.19695 -0.19951 957 GLN A CD  
2175 O OE1 . GLN A 339 ? 1.43982 1.97178 1.77555 0.07162  -0.22425 -0.21947 957 GLN A OE1 
2176 N NE2 . GLN A 339 ? 1.43186 1.79371 1.75506 0.04192  -0.16491 -0.22628 957 GLN A NE2 
# 
