data_9GUY
# 
_entry.id   9GUY 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9GUY         pdb_00009guy 10.2210/pdb9guy/pdb 
WWPDB D_1292141816 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-12-04 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9GUY 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-20 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB 'contains the same protein complex with Tubercidin'              8BSD unspecified 
PDB 'contains the same protein complex with Adenosine'               8BZV unspecified 
PDB 'contains the same protein complex with MTA'                     8C5M unspecified 
PDB 'contains the same protein complex with MTA+GLY'                 8OT0 unspecified 
PDB 'contains the same protein complex with ATP'                     8OSX unspecified 
PDB 'contains the same protein complex with ADP'                     8OV1 unspecified 
PDB 'contains the same protein complex with SAM analog BDH 33959089' 8OTR unspecified 
# 
_pdbx_contact_author.id                 4 
_pdbx_contact_author.email              dominik.oberthuer@desy.de 
_pdbx_contact_author.name_first         Dominik 
_pdbx_contact_author.name_last          Oberthuer 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0894-9590 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Kremling, V.'  1 0000-0002-4877-2902 
'Sprenger, J.'  2 0000-0001-7977-3484 
'Oberthuer, D.' 3 0000-0002-0894-9590 
'Kiene, A.'     4 0000-0001-7480-8027 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Crystal structures of SARS-CoV-2 methyltransferase nsp10-16 with Cap0-site binders' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Kremling, V.'   1  0000-0002-4877-2902 
primary 'Sprenger, J.'   2  0000-0001-7977-3484 
primary 'Oberthuer, D.'  3  0000-0002-0894-9590 
primary 'Chapman, H.N.'  4  0000-0002-4655-1743 
primary 'Middendorf, P.' 5  0000-0002-5243-8384 
primary 'Falke, S.'      6  0000-0003-3409-1791 
primary 'Kiene, A.'      7  0000-0001-7480-8027 
primary 'Klopprogge, B.' 8  0000-0002-0718-1786 
primary 'Scheer, T.E.S.' 9  0009-0000-2377-3127 
primary 'Creon, A.'      10 0009-0005-0266-6759 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 
;2'-O-methyltransferase nsp16
;
34150.090 1   2.1.1.57 ? ? ? 
2 polymer     man 'Non-structural protein 10' 14859.983 1   ?        ? ? ? 
3 non-polymer syn 1,2-ETHANEDIOL 62.068    23  ?        ? ? ? 
4 non-polymer syn '2-(N-MORPHOLINO)-ETHANESULFONIC ACID' 195.237   1   ?        ? ? ? 
5 non-polymer syn 
;~{N}-[(5~{S})-5-azanyl-6-[(3~{S},4~{S},6~{R})-3-[1,3-dimethyl-2,6-bis(oxidanylidene)purin-7-yl]-4-methyl-4,6-bis(oxidanyl)azepan-1-yl]-6-oxidanylidene-hexyl]ethanamide
;
493.557   1   ?        ? ? ? 
6 non-polymer syn S-ADENOSYLMETHIONINE 398.437   1   ?        ? ? ? 
7 non-polymer syn 'CHLORIDE ION' 35.453    3   ?        ? ? ? 
8 non-polymer syn 'ZINC ION' 65.409    2   ?        ? ? ? 
9 water       nat water 18.015    314 ?        ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Non-structural protein 16,nsp16'      
2 'nsp10,Growth factor-like peptide,GFL' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;SSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAP
GTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQK
LALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLS
SYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVNNENLYFQ
;
;SSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAP
GTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQK
LALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLS
SYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVNNENLYFQ
;
B ? 
2 'polypeptide(L)' no no 
;GAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC
HIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQ
;
;GAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC
HIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQ
;
C ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 1,2-ETHANEDIOL EDO   
4 '2-(N-MORPHOLINO)-ETHANESULFONIC ACID' MES   
5 
;~{N}-[(5~{S})-5-azanyl-6-[(3~{S},4~{S},6~{R})-3-[1,3-dimethyl-2,6-bis(oxidanylidene)purin-7-yl]-4-methyl-4,6-bis(oxidanyl)azepan-1-yl]-6-oxidanylidene-hexyl]ethanamide
;
A1IOL 
6 S-ADENOSYLMETHIONINE SAM   
7 'CHLORIDE ION' CL    
8 'ZINC ION' ZN    
9 water HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   SER n 
1 3   GLN n 
1 4   ALA n 
1 5   TRP n 
1 6   GLN n 
1 7   PRO n 
1 8   GLY n 
1 9   VAL n 
1 10  ALA n 
1 11  MET n 
1 12  PRO n 
1 13  ASN n 
1 14  LEU n 
1 15  TYR n 
1 16  LYS n 
1 17  MET n 
1 18  GLN n 
1 19  ARG n 
1 20  MET n 
1 21  LEU n 
1 22  LEU n 
1 23  GLU n 
1 24  LYS n 
1 25  CYS n 
1 26  ASP n 
1 27  LEU n 
1 28  GLN n 
1 29  ASN n 
1 30  TYR n 
1 31  GLY n 
1 32  ASP n 
1 33  SER n 
1 34  ALA n 
1 35  THR n 
1 36  LEU n 
1 37  PRO n 
1 38  LYS n 
1 39  GLY n 
1 40  ILE n 
1 41  MET n 
1 42  MET n 
1 43  ASN n 
1 44  VAL n 
1 45  ALA n 
1 46  LYS n 
1 47  TYR n 
1 48  THR n 
1 49  GLN n 
1 50  LEU n 
1 51  CYS n 
1 52  GLN n 
1 53  TYR n 
1 54  LEU n 
1 55  ASN n 
1 56  THR n 
1 57  LEU n 
1 58  THR n 
1 59  LEU n 
1 60  ALA n 
1 61  VAL n 
1 62  PRO n 
1 63  TYR n 
1 64  ASN n 
1 65  MET n 
1 66  ARG n 
1 67  VAL n 
1 68  ILE n 
1 69  HIS n 
1 70  PHE n 
1 71  GLY n 
1 72  ALA n 
1 73  GLY n 
1 74  SER n 
1 75  ASP n 
1 76  LYS n 
1 77  GLY n 
1 78  VAL n 
1 79  ALA n 
1 80  PRO n 
1 81  GLY n 
1 82  THR n 
1 83  ALA n 
1 84  VAL n 
1 85  LEU n 
1 86  ARG n 
1 87  GLN n 
1 88  TRP n 
1 89  LEU n 
1 90  PRO n 
1 91  THR n 
1 92  GLY n 
1 93  THR n 
1 94  LEU n 
1 95  LEU n 
1 96  VAL n 
1 97  ASP n 
1 98  SER n 
1 99  ASP n 
1 100 LEU n 
1 101 ASN n 
1 102 ASP n 
1 103 PHE n 
1 104 VAL n 
1 105 SER n 
1 106 ASP n 
1 107 ALA n 
1 108 ASP n 
1 109 SER n 
1 110 THR n 
1 111 LEU n 
1 112 ILE n 
1 113 GLY n 
1 114 ASP n 
1 115 CYS n 
1 116 ALA n 
1 117 THR n 
1 118 VAL n 
1 119 HIS n 
1 120 THR n 
1 121 ALA n 
1 122 ASN n 
1 123 LYS n 
1 124 TRP n 
1 125 ASP n 
1 126 LEU n 
1 127 ILE n 
1 128 ILE n 
1 129 SER n 
1 130 ASP n 
1 131 MET n 
1 132 TYR n 
1 133 ASP n 
1 134 PRO n 
1 135 LYS n 
1 136 THR n 
1 137 LYS n 
1 138 ASN n 
1 139 VAL n 
1 140 THR n 
1 141 LYS n 
1 142 GLU n 
1 143 ASN n 
1 144 ASP n 
1 145 SER n 
1 146 LYS n 
1 147 GLU n 
1 148 GLY n 
1 149 PHE n 
1 150 PHE n 
1 151 THR n 
1 152 TYR n 
1 153 ILE n 
1 154 CYS n 
1 155 GLY n 
1 156 PHE n 
1 157 ILE n 
1 158 GLN n 
1 159 GLN n 
1 160 LYS n 
1 161 LEU n 
1 162 ALA n 
1 163 LEU n 
1 164 GLY n 
1 165 GLY n 
1 166 SER n 
1 167 VAL n 
1 168 ALA n 
1 169 ILE n 
1 170 LYS n 
1 171 ILE n 
1 172 THR n 
1 173 GLU n 
1 174 HIS n 
1 175 SER n 
1 176 TRP n 
1 177 ASN n 
1 178 ALA n 
1 179 ASP n 
1 180 LEU n 
1 181 TYR n 
1 182 LYS n 
1 183 LEU n 
1 184 MET n 
1 185 GLY n 
1 186 HIS n 
1 187 PHE n 
1 188 ALA n 
1 189 TRP n 
1 190 TRP n 
1 191 THR n 
1 192 ALA n 
1 193 PHE n 
1 194 VAL n 
1 195 THR n 
1 196 ASN n 
1 197 VAL n 
1 198 ASN n 
1 199 ALA n 
1 200 SER n 
1 201 SER n 
1 202 SER n 
1 203 GLU n 
1 204 ALA n 
1 205 PHE n 
1 206 LEU n 
1 207 ILE n 
1 208 GLY n 
1 209 CYS n 
1 210 ASN n 
1 211 TYR n 
1 212 LEU n 
1 213 GLY n 
1 214 LYS n 
1 215 PRO n 
1 216 ARG n 
1 217 GLU n 
1 218 GLN n 
1 219 ILE n 
1 220 ASP n 
1 221 GLY n 
1 222 TYR n 
1 223 VAL n 
1 224 MET n 
1 225 HIS n 
1 226 ALA n 
1 227 ASN n 
1 228 TYR n 
1 229 ILE n 
1 230 PHE n 
1 231 TRP n 
1 232 ARG n 
1 233 ASN n 
1 234 THR n 
1 235 ASN n 
1 236 PRO n 
1 237 ILE n 
1 238 GLN n 
1 239 LEU n 
1 240 SER n 
1 241 SER n 
1 242 TYR n 
1 243 SER n 
1 244 LEU n 
1 245 PHE n 
1 246 ASP n 
1 247 MET n 
1 248 SER n 
1 249 LYS n 
1 250 PHE n 
1 251 PRO n 
1 252 LEU n 
1 253 LYS n 
1 254 LEU n 
1 255 ARG n 
1 256 GLY n 
1 257 THR n 
1 258 ALA n 
1 259 VAL n 
1 260 MET n 
1 261 SER n 
1 262 LEU n 
1 263 LYS n 
1 264 GLU n 
1 265 GLY n 
1 266 GLN n 
1 267 ILE n 
1 268 ASN n 
1 269 ASP n 
1 270 MET n 
1 271 ILE n 
1 272 LEU n 
1 273 SER n 
1 274 LEU n 
1 275 LEU n 
1 276 SER n 
1 277 LYS n 
1 278 GLY n 
1 279 ARG n 
1 280 LEU n 
1 281 ILE n 
1 282 ILE n 
1 283 ARG n 
1 284 GLU n 
1 285 ASN n 
1 286 ASN n 
1 287 ARG n 
1 288 VAL n 
1 289 VAL n 
1 290 ILE n 
1 291 SER n 
1 292 SER n 
1 293 ASP n 
1 294 VAL n 
1 295 LEU n 
1 296 VAL n 
1 297 ASN n 
1 298 ASN n 
1 299 GLU n 
1 300 ASN n 
1 301 LEU n 
1 302 TYR n 
1 303 PHE n 
1 304 GLN n 
2 1   GLY n 
2 2   ALA n 
2 3   GLY n 
2 4   ASN n 
2 5   ALA n 
2 6   THR n 
2 7   GLU n 
2 8   VAL n 
2 9   PRO n 
2 10  ALA n 
2 11  ASN n 
2 12  SER n 
2 13  THR n 
2 14  VAL n 
2 15  LEU n 
2 16  SER n 
2 17  PHE n 
2 18  CYS n 
2 19  ALA n 
2 20  PHE n 
2 21  ALA n 
2 22  VAL n 
2 23  ASP n 
2 24  ALA n 
2 25  ALA n 
2 26  LYS n 
2 27  ALA n 
2 28  TYR n 
2 29  LYS n 
2 30  ASP n 
2 31  TYR n 
2 32  LEU n 
2 33  ALA n 
2 34  SER n 
2 35  GLY n 
2 36  GLY n 
2 37  GLN n 
2 38  PRO n 
2 39  ILE n 
2 40  THR n 
2 41  ASN n 
2 42  CYS n 
2 43  VAL n 
2 44  LYS n 
2 45  MET n 
2 46  LEU n 
2 47  CYS n 
2 48  THR n 
2 49  HIS n 
2 50  THR n 
2 51  GLY n 
2 52  THR n 
2 53  GLY n 
2 54  GLN n 
2 55  ALA n 
2 56  ILE n 
2 57  THR n 
2 58  VAL n 
2 59  THR n 
2 60  PRO n 
2 61  GLU n 
2 62  ALA n 
2 63  ASN n 
2 64  MET n 
2 65  ASP n 
2 66  GLN n 
2 67  GLU n 
2 68  SER n 
2 69  PHE n 
2 70  GLY n 
2 71  GLY n 
2 72  ALA n 
2 73  SER n 
2 74  CYS n 
2 75  CYS n 
2 76  LEU n 
2 77  TYR n 
2 78  CYS n 
2 79  ARG n 
2 80  CYS n 
2 81  HIS n 
2 82  ILE n 
2 83  ASP n 
2 84  HIS n 
2 85  PRO n 
2 86  ASN n 
2 87  PRO n 
2 88  LYS n 
2 89  GLY n 
2 90  PHE n 
2 91  CYS n 
2 92  ASP n 
2 93  LEU n 
2 94  LYS n 
2 95  GLY n 
2 96  LYS n 
2 97  TYR n 
2 98  VAL n 
2 99  GLN n 
2 100 ILE n 
2 101 PRO n 
2 102 THR n 
2 103 THR n 
2 104 CYS n 
2 105 ALA n 
2 106 ASN n 
2 107 ASP n 
2 108 PRO n 
2 109 VAL n 
2 110 GLY n 
2 111 PHE n 
2 112 THR n 
2 113 LEU n 
2 114 LYS n 
2 115 ASN n 
2 116 THR n 
2 117 VAL n 
2 118 CYS n 
2 119 THR n 
2 120 VAL n 
2 121 CYS n 
2 122 GLY n 
2 123 MET n 
2 124 TRP n 
2 125 LYS n 
2 126 GLY n 
2 127 TYR n 
2 128 GLY n 
2 129 CYS n 
2 130 SER n 
2 131 CYS n 
2 132 ASP n 
2 133 GLN n 
2 134 LEU n 
2 135 ARG n 
2 136 GLU n 
2 137 PRO n 
2 138 MET n 
2 139 LEU n 
2 140 GLN n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 304 ? ? 'rep, 1a-1b' ? ? ? ? ? ? 'Severe acute respiratory syndrome coronavirus 2' 2697049 ? ? 
? ? ? ? ? ? 'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 140 ? ? 'rep, 1a-1b' ? ? ? ? ? ? 'Severe acute respiratory syndrome coronavirus 2' 2697049 ? ? 
? ? ? ? ? ? 'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1IOL non-polymer         . 
;~{N}-[(5~{S})-5-azanyl-6-[(3~{S},4~{S},6~{R})-3-[1,3-dimethyl-2,6-bis(oxidanylidene)purin-7-yl]-4-methyl-4,6-bis(oxidanyl)azepan-1-yl]-6-oxidanylidene-hexyl]ethanamide
;
?                 'C22 H35 N7 O6'   493.557 
ALA   'L-peptide linking' y ALANINE ?                 'C3 H7 N O2'      89.093  
ARG   'L-peptide linking' y ARGININE ?                 'C6 H15 N4 O2 1'  175.209 
ASN   'L-peptide linking' y ASPARAGINE ?                 'C4 H8 N2 O3'     132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ?                 'C4 H7 N O4'      133.103 
CL    non-polymer         . 'CHLORIDE ION' ?                 'Cl -1'           35.453  
CYS   'L-peptide linking' y CYSTEINE ?                 'C3 H7 N O2 S'    121.158 
EDO   non-polymer         . 1,2-ETHANEDIOL 'ETHYLENE GLYCOL' 'C2 H6 O2'        62.068  
GLN   'L-peptide linking' y GLUTAMINE ?                 'C5 H10 N2 O3'    146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ?                 'C5 H9 N O4'      147.129 
GLY   'peptide linking'   y GLYCINE ?                 'C2 H5 N O2'      75.067  
HIS   'L-peptide linking' y HISTIDINE ?                 'C6 H10 N3 O2 1'  156.162 
HOH   non-polymer         . WATER ?                 'H2 O'            18.015  
ILE   'L-peptide linking' y ISOLEUCINE ?                 'C6 H13 N O2'     131.173 
LEU   'L-peptide linking' y LEUCINE ?                 'C6 H13 N O2'     131.173 
LYS   'L-peptide linking' y LYSINE ?                 'C6 H15 N2 O2 1'  147.195 
MES   non-polymer         . '2-(N-MORPHOLINO)-ETHANESULFONIC ACID' ?                 'C6 H13 N O4 S'   195.237 
MET   'L-peptide linking' y METHIONINE ?                 'C5 H11 N O2 S'   149.211 
PHE   'L-peptide linking' y PHENYLALANINE ?                 'C9 H11 N O2'     165.189 
PRO   'L-peptide linking' y PROLINE ?                 'C5 H9 N O2'      115.130 
SAM   non-polymer         . S-ADENOSYLMETHIONINE ?                 'C15 H22 N6 O5 S' 398.437 
SER   'L-peptide linking' y SERINE ?                 'C3 H7 N O3'      105.093 
THR   'L-peptide linking' y THREONINE ?                 'C4 H9 N O3'      119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ?                 'C11 H12 N2 O2'   204.225 
TYR   'L-peptide linking' y TYROSINE ?                 'C9 H11 N O3'     181.189 
VAL   'L-peptide linking' y VALINE ?                 'C5 H11 N O2'     117.146 
ZN    non-polymer         . 'ZINC ION' ?                 'Zn 2'            65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   6799 6799 SER SER B . n 
A 1 2   SER 2   6800 6800 SER SER B . n 
A 1 3   GLN 3   6801 6801 GLN GLN B . n 
A 1 4   ALA 4   6802 6802 ALA ALA B . n 
A 1 5   TRP 5   6803 6803 TRP TRP B . n 
A 1 6   GLN 6   6804 6804 GLN GLN B . n 
A 1 7   PRO 7   6805 6805 PRO PRO B . n 
A 1 8   GLY 8   6806 6806 GLY GLY B . n 
A 1 9   VAL 9   6807 6807 VAL VAL B . n 
A 1 10  ALA 10  6808 6808 ALA ALA B . n 
A 1 11  MET 11  6809 6809 MET MET B . n 
A 1 12  PRO 12  6810 6810 PRO PRO B . n 
A 1 13  ASN 13  6811 6811 ASN ASN B . n 
A 1 14  LEU 14  6812 6812 LEU LEU B . n 
A 1 15  TYR 15  6813 6813 TYR TYR B . n 
A 1 16  LYS 16  6814 6814 LYS LYS B . n 
A 1 17  MET 17  6815 6815 MET MET B . n 
A 1 18  GLN 18  6816 6816 GLN GLN B . n 
A 1 19  ARG 19  6817 6817 ARG ARG B . n 
A 1 20  MET 20  6818 6818 MET MET B . n 
A 1 21  LEU 21  6819 6819 LEU LEU B . n 
A 1 22  LEU 22  6820 6820 LEU LEU B . n 
A 1 23  GLU 23  6821 6821 GLU GLU B . n 
A 1 24  LYS 24  6822 6822 LYS LYS B . n 
A 1 25  CYS 25  6823 6823 CYS CYS B . n 
A 1 26  ASP 26  6824 6824 ASP ASP B . n 
A 1 27  LEU 27  6825 6825 LEU LEU B . n 
A 1 28  GLN 28  6826 6826 GLN GLN B . n 
A 1 29  ASN 29  6827 6827 ASN ASN B . n 
A 1 30  TYR 30  6828 6828 TYR TYR B . n 
A 1 31  GLY 31  6829 6829 GLY GLY B . n 
A 1 32  ASP 32  6830 6830 ASP ASP B . n 
A 1 33  SER 33  6831 6831 SER SER B . n 
A 1 34  ALA 34  6832 6832 ALA ALA B . n 
A 1 35  THR 35  6833 6833 THR THR B . n 
A 1 36  LEU 36  6834 6834 LEU LEU B . n 
A 1 37  PRO 37  6835 6835 PRO PRO B . n 
A 1 38  LYS 38  6836 6836 LYS LYS B . n 
A 1 39  GLY 39  6837 6837 GLY GLY B . n 
A 1 40  ILE 40  6838 6838 ILE ILE B . n 
A 1 41  MET 41  6839 6839 MET MET B . n 
A 1 42  MET 42  6840 6840 MET MET B . n 
A 1 43  ASN 43  6841 6841 ASN ASN B . n 
A 1 44  VAL 44  6842 6842 VAL VAL B . n 
A 1 45  ALA 45  6843 6843 ALA ALA B . n 
A 1 46  LYS 46  6844 6844 LYS LYS B . n 
A 1 47  TYR 47  6845 6845 TYR TYR B . n 
A 1 48  THR 48  6846 6846 THR THR B . n 
A 1 49  GLN 49  6847 6847 GLN GLN B . n 
A 1 50  LEU 50  6848 6848 LEU LEU B . n 
A 1 51  CYS 51  6849 6849 CYS CYS B . n 
A 1 52  GLN 52  6850 6850 GLN GLN B . n 
A 1 53  TYR 53  6851 6851 TYR TYR B . n 
A 1 54  LEU 54  6852 6852 LEU LEU B . n 
A 1 55  ASN 55  6853 6853 ASN ASN B . n 
A 1 56  THR 56  6854 6854 THR THR B . n 
A 1 57  LEU 57  6855 6855 LEU LEU B . n 
A 1 58  THR 58  6856 6856 THR THR B . n 
A 1 59  LEU 59  6857 6857 LEU LEU B . n 
A 1 60  ALA 60  6858 6858 ALA ALA B . n 
A 1 61  VAL 61  6859 6859 VAL VAL B . n 
A 1 62  PRO 62  6860 6860 PRO PRO B . n 
A 1 63  TYR 63  6861 6861 TYR TYR B . n 
A 1 64  ASN 64  6862 6862 ASN ASN B . n 
A 1 65  MET 65  6863 6863 MET MET B . n 
A 1 66  ARG 66  6864 6864 ARG ARG B . n 
A 1 67  VAL 67  6865 6865 VAL VAL B . n 
A 1 68  ILE 68  6866 6866 ILE ILE B . n 
A 1 69  HIS 69  6867 6867 HIS HIS B . n 
A 1 70  PHE 70  6868 6868 PHE PHE B . n 
A 1 71  GLY 71  6869 6869 GLY GLY B . n 
A 1 72  ALA 72  6870 6870 ALA ALA B . n 
A 1 73  GLY 73  6871 6871 GLY GLY B . n 
A 1 74  SER 74  6872 6872 SER SER B . n 
A 1 75  ASP 75  6873 6873 ASP ASP B . n 
A 1 76  LYS 76  6874 6874 LYS LYS B . n 
A 1 77  GLY 77  6875 6875 GLY GLY B . n 
A 1 78  VAL 78  6876 6876 VAL VAL B . n 
A 1 79  ALA 79  6877 6877 ALA ALA B . n 
A 1 80  PRO 80  6878 6878 PRO PRO B . n 
A 1 81  GLY 81  6879 6879 GLY GLY B . n 
A 1 82  THR 82  6880 6880 THR THR B . n 
A 1 83  ALA 83  6881 6881 ALA ALA B . n 
A 1 84  VAL 84  6882 6882 VAL VAL B . n 
A 1 85  LEU 85  6883 6883 LEU LEU B . n 
A 1 86  ARG 86  6884 6884 ARG ARG B . n 
A 1 87  GLN 87  6885 6885 GLN GLN B . n 
A 1 88  TRP 88  6886 6886 TRP TRP B . n 
A 1 89  LEU 89  6887 6887 LEU LEU B . n 
A 1 90  PRO 90  6888 6888 PRO PRO B . n 
A 1 91  THR 91  6889 6889 THR THR B . n 
A 1 92  GLY 92  6890 6890 GLY GLY B . n 
A 1 93  THR 93  6891 6891 THR THR B . n 
A 1 94  LEU 94  6892 6892 LEU LEU B . n 
A 1 95  LEU 95  6893 6893 LEU LEU B . n 
A 1 96  VAL 96  6894 6894 VAL VAL B . n 
A 1 97  ASP 97  6895 6895 ASP ASP B . n 
A 1 98  SER 98  6896 6896 SER SER B . n 
A 1 99  ASP 99  6897 6897 ASP ASP B . n 
A 1 100 LEU 100 6898 6898 LEU LEU B . n 
A 1 101 ASN 101 6899 6899 ASN ASN B . n 
A 1 102 ASP 102 6900 6900 ASP ASP B . n 
A 1 103 PHE 103 6901 6901 PHE PHE B . n 
A 1 104 VAL 104 6902 6902 VAL VAL B . n 
A 1 105 SER 105 6903 6903 SER SER B . n 
A 1 106 ASP 106 6904 6904 ASP ASP B . n 
A 1 107 ALA 107 6905 6905 ALA ALA B . n 
A 1 108 ASP 108 6906 6906 ASP ASP B . n 
A 1 109 SER 109 6907 6907 SER SER B . n 
A 1 110 THR 110 6908 6908 THR THR B . n 
A 1 111 LEU 111 6909 6909 LEU LEU B . n 
A 1 112 ILE 112 6910 6910 ILE ILE B . n 
A 1 113 GLY 113 6911 6911 GLY GLY B . n 
A 1 114 ASP 114 6912 6912 ASP ASP B . n 
A 1 115 CYS 115 6913 6913 CYS CYS B . n 
A 1 116 ALA 116 6914 6914 ALA ALA B . n 
A 1 117 THR 117 6915 6915 THR THR B . n 
A 1 118 VAL 118 6916 6916 VAL VAL B . n 
A 1 119 HIS 119 6917 6917 HIS HIS B . n 
A 1 120 THR 120 6918 6918 THR THR B . n 
A 1 121 ALA 121 6919 6919 ALA ALA B . n 
A 1 122 ASN 122 6920 6920 ASN ASN B . n 
A 1 123 LYS 123 6921 6921 LYS LYS B . n 
A 1 124 TRP 124 6922 6922 TRP TRP B . n 
A 1 125 ASP 125 6923 6923 ASP ASP B . n 
A 1 126 LEU 126 6924 6924 LEU LEU B . n 
A 1 127 ILE 127 6925 6925 ILE ILE B . n 
A 1 128 ILE 128 6926 6926 ILE ILE B . n 
A 1 129 SER 129 6927 6927 SER SER B . n 
A 1 130 ASP 130 6928 6928 ASP ASP B . n 
A 1 131 MET 131 6929 6929 MET MET B . n 
A 1 132 TYR 132 6930 6930 TYR TYR B . n 
A 1 133 ASP 133 6931 6931 ASP ASP B . n 
A 1 134 PRO 134 6932 6932 PRO PRO B . n 
A 1 135 LYS 135 6933 6933 LYS LYS B . n 
A 1 136 THR 136 6934 6934 THR THR B . n 
A 1 137 LYS 137 6935 6935 LYS LYS B . n 
A 1 138 ASN 138 6936 6936 ASN ASN B . n 
A 1 139 VAL 139 6937 6937 VAL VAL B . n 
A 1 140 THR 140 6938 6938 THR THR B . n 
A 1 141 LYS 141 6939 6939 LYS LYS B . n 
A 1 142 GLU 142 6940 6940 GLU GLU B . n 
A 1 143 ASN 143 6941 6941 ASN ASN B . n 
A 1 144 ASP 144 6942 6942 ASP ASP B . n 
A 1 145 SER 145 6943 6943 SER SER B . n 
A 1 146 LYS 146 6944 6944 LYS LYS B . n 
A 1 147 GLU 147 6945 6945 GLU GLU B . n 
A 1 148 GLY 148 6946 6946 GLY GLY B . n 
A 1 149 PHE 149 6947 6947 PHE PHE B . n 
A 1 150 PHE 150 6948 6948 PHE PHE B . n 
A 1 151 THR 151 6949 6949 THR THR B . n 
A 1 152 TYR 152 6950 6950 TYR TYR B . n 
A 1 153 ILE 153 6951 6951 ILE ILE B . n 
A 1 154 CYS 154 6952 6952 CYS CYS B . n 
A 1 155 GLY 155 6953 6953 GLY GLY B . n 
A 1 156 PHE 156 6954 6954 PHE PHE B . n 
A 1 157 ILE 157 6955 6955 ILE ILE B . n 
A 1 158 GLN 158 6956 6956 GLN GLN B . n 
A 1 159 GLN 159 6957 6957 GLN GLN B . n 
A 1 160 LYS 160 6958 6958 LYS LYS B . n 
A 1 161 LEU 161 6959 6959 LEU LEU B . n 
A 1 162 ALA 162 6960 6960 ALA ALA B . n 
A 1 163 LEU 163 6961 6961 LEU LEU B . n 
A 1 164 GLY 164 6962 6962 GLY GLY B . n 
A 1 165 GLY 165 6963 6963 GLY GLY B . n 
A 1 166 SER 166 6964 6964 SER SER B . n 
A 1 167 VAL 167 6965 6965 VAL VAL B . n 
A 1 168 ALA 168 6966 6966 ALA ALA B . n 
A 1 169 ILE 169 6967 6967 ILE ILE B . n 
A 1 170 LYS 170 6968 6968 LYS LYS B . n 
A 1 171 ILE 171 6969 6969 ILE ILE B . n 
A 1 172 THR 172 6970 6970 THR THR B . n 
A 1 173 GLU 173 6971 6971 GLU GLU B . n 
A 1 174 HIS 174 6972 6972 HIS HIS B . n 
A 1 175 SER 175 6973 6973 SER SER B . n 
A 1 176 TRP 176 6974 6974 TRP TRP B . n 
A 1 177 ASN 177 6975 6975 ASN ASN B . n 
A 1 178 ALA 178 6976 6976 ALA ALA B . n 
A 1 179 ASP 179 6977 6977 ASP ASP B . n 
A 1 180 LEU 180 6978 6978 LEU LEU B . n 
A 1 181 TYR 181 6979 6979 TYR TYR B . n 
A 1 182 LYS 182 6980 6980 LYS LYS B . n 
A 1 183 LEU 183 6981 6981 LEU LEU B . n 
A 1 184 MET 184 6982 6982 MET MET B . n 
A 1 185 GLY 185 6983 6983 GLY GLY B . n 
A 1 186 HIS 186 6984 6984 HIS HIS B . n 
A 1 187 PHE 187 6985 6985 PHE PHE B . n 
A 1 188 ALA 188 6986 6986 ALA ALA B . n 
A 1 189 TRP 189 6987 6987 TRP TRP B . n 
A 1 190 TRP 190 6988 6988 TRP TRP B . n 
A 1 191 THR 191 6989 6989 THR THR B . n 
A 1 192 ALA 192 6990 6990 ALA ALA B . n 
A 1 193 PHE 193 6991 6991 PHE PHE B . n 
A 1 194 VAL 194 6992 6992 VAL VAL B . n 
A 1 195 THR 195 6993 6993 THR THR B . n 
A 1 196 ASN 196 6994 6994 ASN ASN B . n 
A 1 197 VAL 197 6995 6995 VAL VAL B . n 
A 1 198 ASN 198 6996 6996 ASN ASN B . n 
A 1 199 ALA 199 6997 6997 ALA ALA B . n 
A 1 200 SER 200 6998 6998 SER SER B . n 
A 1 201 SER 201 6999 6999 SER SER B . n 
A 1 202 SER 202 7000 7000 SER SER B . n 
A 1 203 GLU 203 7001 7001 GLU GLU B . n 
A 1 204 ALA 204 7002 7002 ALA ALA B . n 
A 1 205 PHE 205 7003 7003 PHE PHE B . n 
A 1 206 LEU 206 7004 7004 LEU LEU B . n 
A 1 207 ILE 207 7005 7005 ILE ILE B . n 
A 1 208 GLY 208 7006 7006 GLY GLY B . n 
A 1 209 CYS 209 7007 7007 CYS CYS B . n 
A 1 210 ASN 210 7008 7008 ASN ASN B . n 
A 1 211 TYR 211 7009 7009 TYR TYR B . n 
A 1 212 LEU 212 7010 7010 LEU LEU B . n 
A 1 213 GLY 213 7011 7011 GLY GLY B . n 
A 1 214 LYS 214 7012 7012 LYS LYS B . n 
A 1 215 PRO 215 7013 7013 PRO PRO B . n 
A 1 216 ARG 216 7014 7014 ARG ARG B . n 
A 1 217 GLU 217 7015 7015 GLU GLU B . n 
A 1 218 GLN 218 7016 7016 GLN GLN B . n 
A 1 219 ILE 219 7017 7017 ILE ILE B . n 
A 1 220 ASP 220 7018 7018 ASP ASP B . n 
A 1 221 GLY 221 7019 7019 GLY GLY B . n 
A 1 222 TYR 222 7020 7020 TYR TYR B . n 
A 1 223 VAL 223 7021 7021 VAL VAL B . n 
A 1 224 MET 224 7022 7022 MET MET B . n 
A 1 225 HIS 225 7023 7023 HIS HIS B . n 
A 1 226 ALA 226 7024 7024 ALA ALA B . n 
A 1 227 ASN 227 7025 7025 ASN ASN B . n 
A 1 228 TYR 228 7026 7026 TYR TYR B . n 
A 1 229 ILE 229 7027 7027 ILE ILE B . n 
A 1 230 PHE 230 7028 7028 PHE PHE B . n 
A 1 231 TRP 231 7029 7029 TRP TRP B . n 
A 1 232 ARG 232 7030 7030 ARG ARG B . n 
A 1 233 ASN 233 7031 7031 ASN ASN B . n 
A 1 234 THR 234 7032 7032 THR THR B . n 
A 1 235 ASN 235 7033 7033 ASN ASN B . n 
A 1 236 PRO 236 7034 7034 PRO PRO B . n 
A 1 237 ILE 237 7035 7035 ILE ILE B . n 
A 1 238 GLN 238 7036 7036 GLN GLN B . n 
A 1 239 LEU 239 7037 7037 LEU LEU B . n 
A 1 240 SER 240 7038 7038 SER SER B . n 
A 1 241 SER 241 7039 7039 SER SER B . n 
A 1 242 TYR 242 7040 7040 TYR TYR B . n 
A 1 243 SER 243 7041 7041 SER SER B . n 
A 1 244 LEU 244 7042 7042 LEU LEU B . n 
A 1 245 PHE 245 7043 7043 PHE PHE B . n 
A 1 246 ASP 246 7044 7044 ASP ASP B . n 
A 1 247 MET 247 7045 7045 MET MET B . n 
A 1 248 SER 248 7046 7046 SER SER B . n 
A 1 249 LYS 249 7047 7047 LYS LYS B . n 
A 1 250 PHE 250 7048 7048 PHE PHE B . n 
A 1 251 PRO 251 7049 7049 PRO PRO B . n 
A 1 252 LEU 252 7050 7050 LEU LEU B . n 
A 1 253 LYS 253 7051 7051 LYS LYS B . n 
A 1 254 LEU 254 7052 7052 LEU LEU B . n 
A 1 255 ARG 255 7053 7053 ARG ARG B . n 
A 1 256 GLY 256 7054 7054 GLY GLY B . n 
A 1 257 THR 257 7055 7055 THR THR B . n 
A 1 258 ALA 258 7056 7056 ALA ALA B . n 
A 1 259 VAL 259 7057 7057 VAL VAL B . n 
A 1 260 MET 260 7058 7058 MET MET B . n 
A 1 261 SER 261 7059 7059 SER SER B . n 
A 1 262 LEU 262 7060 7060 LEU LEU B . n 
A 1 263 LYS 263 7061 7061 LYS LYS B . n 
A 1 264 GLU 264 7062 7062 GLU GLU B . n 
A 1 265 GLY 265 7063 7063 GLY GLY B . n 
A 1 266 GLN 266 7064 7064 GLN GLN B . n 
A 1 267 ILE 267 7065 7065 ILE ILE B . n 
A 1 268 ASN 268 7066 7066 ASN ASN B . n 
A 1 269 ASP 269 7067 7067 ASP ASP B . n 
A 1 270 MET 270 7068 7068 MET MET B . n 
A 1 271 ILE 271 7069 7069 ILE ILE B . n 
A 1 272 LEU 272 7070 7070 LEU LEU B . n 
A 1 273 SER 273 7071 7071 SER SER B . n 
A 1 274 LEU 274 7072 7072 LEU LEU B . n 
A 1 275 LEU 275 7073 7073 LEU LEU B . n 
A 1 276 SER 276 7074 7074 SER SER B . n 
A 1 277 LYS 277 7075 7075 LYS LYS B . n 
A 1 278 GLY 278 7076 7076 GLY GLY B . n 
A 1 279 ARG 279 7077 7077 ARG ARG B . n 
A 1 280 LEU 280 7078 7078 LEU LEU B . n 
A 1 281 ILE 281 7079 7079 ILE ILE B . n 
A 1 282 ILE 282 7080 7080 ILE ILE B . n 
A 1 283 ARG 283 7081 7081 ARG ARG B . n 
A 1 284 GLU 284 7082 7082 GLU GLU B . n 
A 1 285 ASN 285 7083 7083 ASN ASN B . n 
A 1 286 ASN 286 7084 7084 ASN ASN B . n 
A 1 287 ARG 287 7085 7085 ARG ARG B . n 
A 1 288 VAL 288 7086 7086 VAL VAL B . n 
A 1 289 VAL 289 7087 7087 VAL VAL B . n 
A 1 290 ILE 290 7088 7088 ILE ILE B . n 
A 1 291 SER 291 7089 7089 SER SER B . n 
A 1 292 SER 292 7090 7090 SER SER B . n 
A 1 293 ASP 293 7091 7091 ASP ASP B . n 
A 1 294 VAL 294 7092 7092 VAL VAL B . n 
A 1 295 LEU 295 7093 7093 LEU LEU B . n 
A 1 296 VAL 296 7094 7094 VAL VAL B . n 
A 1 297 ASN 297 7095 7095 ASN ASN B . n 
A 1 298 ASN 298 7096 7096 ASN ASN B . n 
A 1 299 GLU 299 7097 7097 GLU GLU B . n 
A 1 300 ASN 300 7098 7098 ASN ASN B . n 
A 1 301 LEU 301 7099 7099 LEU LEU B . n 
A 1 302 TYR 302 7100 ?    ?   ?   B . n 
A 1 303 PHE 303 7101 ?    ?   ?   B . n 
A 1 304 GLN 304 7102 ?    ?   ?   B . n 
B 2 1   GLY 1   4253 ?    ?   ?   C . n 
B 2 2   ALA 2   4254 ?    ?   ?   C . n 
B 2 3   GLY 3   4255 ?    ?   ?   C . n 
B 2 4   ASN 4   4256 ?    ?   ?   C . n 
B 2 5   ALA 5   4257 ?    ?   ?   C . n 
B 2 6   THR 6   4258 ?    ?   ?   C . n 
B 2 7   GLU 7   4259 ?    ?   ?   C . n 
B 2 8   VAL 8   4260 ?    ?   ?   C . n 
B 2 9   PRO 9   4261 ?    ?   ?   C . n 
B 2 10  ALA 10  4262 ?    ?   ?   C . n 
B 2 11  ASN 11  4263 ?    ?   ?   C . n 
B 2 12  SER 12  4264 ?    ?   ?   C . n 
B 2 13  THR 13  4265 ?    ?   ?   C . n 
B 2 14  VAL 14  4266 ?    ?   ?   C . n 
B 2 15  LEU 15  4267 ?    ?   ?   C . n 
B 2 16  SER 16  4268 ?    ?   ?   C . n 
B 2 17  PHE 17  4269 ?    ?   ?   C . n 
B 2 18  CYS 18  4270 ?    ?   ?   C . n 
B 2 19  ALA 19  4271 4271 ALA ALA C . n 
B 2 20  PHE 20  4272 4272 PHE PHE C . n 
B 2 21  ALA 21  4273 4273 ALA ALA C . n 
B 2 22  VAL 22  4274 4274 VAL VAL C . n 
B 2 23  ASP 23  4275 4275 ASP ASP C . n 
B 2 24  ALA 24  4276 4276 ALA ALA C . n 
B 2 25  ALA 25  4277 4277 ALA ALA C . n 
B 2 26  LYS 26  4278 4278 LYS LYS C . n 
B 2 27  ALA 27  4279 4279 ALA ALA C . n 
B 2 28  TYR 28  4280 4280 TYR TYR C . n 
B 2 29  LYS 29  4281 4281 LYS LYS C . n 
B 2 30  ASP 30  4282 4282 ASP ASP C . n 
B 2 31  TYR 31  4283 4283 TYR TYR C . n 
B 2 32  LEU 32  4284 4284 LEU LEU C . n 
B 2 33  ALA 33  4285 4285 ALA ALA C . n 
B 2 34  SER 34  4286 4286 SER SER C . n 
B 2 35  GLY 35  4287 4287 GLY GLY C . n 
B 2 36  GLY 36  4288 4288 GLY GLY C . n 
B 2 37  GLN 37  4289 4289 GLN GLN C . n 
B 2 38  PRO 38  4290 4290 PRO PRO C . n 
B 2 39  ILE 39  4291 4291 ILE ILE C . n 
B 2 40  THR 40  4292 4292 THR THR C . n 
B 2 41  ASN 41  4293 4293 ASN ASN C . n 
B 2 42  CYS 42  4294 4294 CYS CYS C . n 
B 2 43  VAL 43  4295 4295 VAL VAL C . n 
B 2 44  LYS 44  4296 4296 LYS LYS C . n 
B 2 45  MET 45  4297 4297 MET MET C . n 
B 2 46  LEU 46  4298 4298 LEU LEU C . n 
B 2 47  CYS 47  4299 4299 CYS CYS C . n 
B 2 48  THR 48  4300 4300 THR THR C . n 
B 2 49  HIS 49  4301 4301 HIS HIS C . n 
B 2 50  THR 50  4302 4302 THR THR C . n 
B 2 51  GLY 51  4303 4303 GLY GLY C . n 
B 2 52  THR 52  4304 4304 THR THR C . n 
B 2 53  GLY 53  4305 4305 GLY GLY C . n 
B 2 54  GLN 54  4306 4306 GLN GLN C . n 
B 2 55  ALA 55  4307 4307 ALA ALA C . n 
B 2 56  ILE 56  4308 4308 ILE ILE C . n 
B 2 57  THR 57  4309 4309 THR THR C . n 
B 2 58  VAL 58  4310 4310 VAL VAL C . n 
B 2 59  THR 59  4311 4311 THR THR C . n 
B 2 60  PRO 60  4312 4312 PRO PRO C . n 
B 2 61  GLU 61  4313 4313 GLU GLU C . n 
B 2 62  ALA 62  4314 4314 ALA ALA C . n 
B 2 63  ASN 63  4315 4315 ASN ASN C . n 
B 2 64  MET 64  4316 4316 MET MET C . n 
B 2 65  ASP 65  4317 4317 ASP ASP C . n 
B 2 66  GLN 66  4318 4318 GLN GLN C . n 
B 2 67  GLU 67  4319 4319 GLU GLU C . n 
B 2 68  SER 68  4320 4320 SER SER C . n 
B 2 69  PHE 69  4321 4321 PHE PHE C . n 
B 2 70  GLY 70  4322 4322 GLY GLY C . n 
B 2 71  GLY 71  4323 4323 GLY GLY C . n 
B 2 72  ALA 72  4324 4324 ALA ALA C . n 
B 2 73  SER 73  4325 4325 SER SER C . n 
B 2 74  CYS 74  4326 4326 CYS CYS C . n 
B 2 75  CYS 75  4327 4327 CYS CYS C . n 
B 2 76  LEU 76  4328 4328 LEU LEU C . n 
B 2 77  TYR 77  4329 4329 TYR TYR C . n 
B 2 78  CYS 78  4330 4330 CYS CYS C . n 
B 2 79  ARG 79  4331 4331 ARG ARG C . n 
B 2 80  CYS 80  4332 4332 CYS CYS C . n 
B 2 81  HIS 81  4333 4333 HIS HIS C . n 
B 2 82  ILE 82  4334 4334 ILE ILE C . n 
B 2 83  ASP 83  4335 4335 ASP ASP C . n 
B 2 84  HIS 84  4336 4336 HIS HIS C . n 
B 2 85  PRO 85  4337 4337 PRO PRO C . n 
B 2 86  ASN 86  4338 4338 ASN ASN C . n 
B 2 87  PRO 87  4339 4339 PRO PRO C . n 
B 2 88  LYS 88  4340 4340 LYS LYS C . n 
B 2 89  GLY 89  4341 4341 GLY GLY C . n 
B 2 90  PHE 90  4342 4342 PHE PHE C . n 
B 2 91  CYS 91  4343 4343 CYS CYS C . n 
B 2 92  ASP 92  4344 4344 ASP ASP C . n 
B 2 93  LEU 93  4345 4345 LEU LEU C . n 
B 2 94  LYS 94  4346 4346 LYS LYS C . n 
B 2 95  GLY 95  4347 4347 GLY GLY C . n 
B 2 96  LYS 96  4348 4348 LYS LYS C . n 
B 2 97  TYR 97  4349 4349 TYR TYR C . n 
B 2 98  VAL 98  4350 4350 VAL VAL C . n 
B 2 99  GLN 99  4351 4351 GLN GLN C . n 
B 2 100 ILE 100 4352 4352 ILE ILE C . n 
B 2 101 PRO 101 4353 4353 PRO PRO C . n 
B 2 102 THR 102 4354 4354 THR THR C . n 
B 2 103 THR 103 4355 4355 THR THR C . n 
B 2 104 CYS 104 4356 4356 CYS CYS C . n 
B 2 105 ALA 105 4357 4357 ALA ALA C . n 
B 2 106 ASN 106 4358 4358 ASN ASN C . n 
B 2 107 ASP 107 4359 4359 ASP ASP C . n 
B 2 108 PRO 108 4360 4360 PRO PRO C . n 
B 2 109 VAL 109 4361 4361 VAL VAL C . n 
B 2 110 GLY 110 4362 4362 GLY GLY C . n 
B 2 111 PHE 111 4363 4363 PHE PHE C . n 
B 2 112 THR 112 4364 4364 THR THR C . n 
B 2 113 LEU 113 4365 4365 LEU LEU C . n 
B 2 114 LYS 114 4366 4366 LYS LYS C . n 
B 2 115 ASN 115 4367 4367 ASN ASN C . n 
B 2 116 THR 116 4368 4368 THR THR C . n 
B 2 117 VAL 117 4369 4369 VAL VAL C . n 
B 2 118 CYS 118 4370 4370 CYS CYS C . n 
B 2 119 THR 119 4371 4371 THR THR C . n 
B 2 120 VAL 120 4372 4372 VAL VAL C . n 
B 2 121 CYS 121 4373 4373 CYS CYS C . n 
B 2 122 GLY 122 4374 4374 GLY GLY C . n 
B 2 123 MET 123 4375 4375 MET MET C . n 
B 2 124 TRP 124 4376 4376 TRP TRP C . n 
B 2 125 LYS 125 4377 4377 LYS LYS C . n 
B 2 126 GLY 126 4378 4378 GLY GLY C . n 
B 2 127 TYR 127 4379 4379 TYR TYR C . n 
B 2 128 GLY 128 4380 4380 GLY GLY C . n 
B 2 129 CYS 129 4381 4381 CYS CYS C . n 
B 2 130 SER 130 4382 4382 SER SER C . n 
B 2 131 CYS 131 4383 4383 CYS CYS C . n 
B 2 132 ASP 132 4384 4384 ASP ASP C . n 
B 2 133 GLN 133 4385 4385 GLN GLN C . n 
B 2 134 LEU 134 4386 ?    ?   ?   C . n 
B 2 135 ARG 135 4387 ?    ?   ?   C . n 
B 2 136 GLU 136 4388 ?    ?   ?   C . n 
B 2 137 PRO 137 4389 ?    ?   ?   C . n 
B 2 138 MET 138 4390 ?    ?   ?   C . n 
B 2 139 LEU 139 4391 ?    ?   ?   C . n 
B 2 140 GLN 140 4392 ?    ?   ?   C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1IOL 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1IOL 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C  3 EDO   1   7201 7905 EDO   EDO B . 
D  4 MES   1   7202 7906 MES   MES B . 
E  3 EDO   1   7203 7907 EDO   EDO B . 
F  3 EDO   1   7204 7909 EDO   EDO B . 
G  3 EDO   1   7205 7911 EDO   EDO B . 
H  3 EDO   1   7206 7913 EDO   EDO B . 
I  3 EDO   1   7207 7920 EDO   EDO B . 
J  3 EDO   1   7208 7923 EDO   EDO B . 
K  3 EDO   1   7209 7931 EDO   EDO B . 
L  3 EDO   1   7210 7940 EDO   EDO B . 
M  3 EDO   1   7211 7942 EDO   EDO B . 
N  3 EDO   1   7212 7945 EDO   EDO B . 
O  3 EDO   1   7213 7946 EDO   EDO B . 
P  3 EDO   1   7214 7950 EDO   EDO B . 
Q  3 EDO   1   7215 7952 EDO   EDO B . 
R  3 EDO   1   7216 7953 EDO   EDO B . 
S  3 EDO   1   7217 7965 EDO   EDO B . 
T  3 EDO   1   7218 7967 EDO   EDO B . 
U  5 A1IOL 1   7219 7976 A1IOL C02 B . 
V  6 SAM   1   7220 1    SAM   SAM B . 
W  7 CL    1   7221 1    CL    CL  B . 
X  7 CL    1   7222 3    CL    CL  B . 
Y  3 EDO   1   7223 7    EDO   EDO B . 
Z  3 EDO   1   7224 8    EDO   EDO B . 
AA 3 EDO   1   7225 10   EDO   EDO B . 
BA 3 EDO   1   7226 11   EDO   EDO B . 
CA 8 ZN    1   4401 8654 ZN    ZN  C . 
DA 8 ZN    1   4402 8655 ZN    ZN  C . 
EA 3 EDO   1   4403 8656 EDO   EDO C . 
FA 7 CL    1   4404 2    CL    CL  C . 
GA 3 EDO   1   4405 4    EDO   EDO C . 
HA 9 HOH   1   7301 284  HOH   HOH B . 
HA 9 HOH   2   7302 78   HOH   HOH B . 
HA 9 HOH   3   7303 360  HOH   HOH B . 
HA 9 HOH   4   7304 415  HOH   HOH B . 
HA 9 HOH   5   7305 275  HOH   HOH B . 
HA 9 HOH   6   7306 162  HOH   HOH B . 
HA 9 HOH   7   7307 386  HOH   HOH B . 
HA 9 HOH   8   7308 54   HOH   HOH B . 
HA 9 HOH   9   7309 6    HOH   HOH B . 
HA 9 HOH   10  7310 238  HOH   HOH B . 
HA 9 HOH   11  7311 85   HOH   HOH B . 
HA 9 HOH   12  7312 414  HOH   HOH B . 
HA 9 HOH   13  7313 24   HOH   HOH B . 
HA 9 HOH   14  7314 37   HOH   HOH B . 
HA 9 HOH   15  7315 249  HOH   HOH B . 
HA 9 HOH   16  7316 44   HOH   HOH B . 
HA 9 HOH   17  7317 214  HOH   HOH B . 
HA 9 HOH   18  7318 28   HOH   HOH B . 
HA 9 HOH   19  7319 235  HOH   HOH B . 
HA 9 HOH   20  7320 353  HOH   HOH B . 
HA 9 HOH   21  7321 36   HOH   HOH B . 
HA 9 HOH   22  7322 31   HOH   HOH B . 
HA 9 HOH   23  7323 318  HOH   HOH B . 
HA 9 HOH   24  7324 115  HOH   HOH B . 
HA 9 HOH   25  7325 88   HOH   HOH B . 
HA 9 HOH   26  7326 164  HOH   HOH B . 
HA 9 HOH   27  7327 29   HOH   HOH B . 
HA 9 HOH   28  7328 1    HOH   HOH B . 
HA 9 HOH   29  7329 108  HOH   HOH B . 
HA 9 HOH   30  7330 330  HOH   HOH B . 
HA 9 HOH   31  7331 51   HOH   HOH B . 
HA 9 HOH   32  7332 5    HOH   HOH B . 
HA 9 HOH   33  7333 27   HOH   HOH B . 
HA 9 HOH   34  7334 59   HOH   HOH B . 
HA 9 HOH   35  7335 46   HOH   HOH B . 
HA 9 HOH   36  7336 365  HOH   HOH B . 
HA 9 HOH   37  7337 21   HOH   HOH B . 
HA 9 HOH   38  7338 62   HOH   HOH B . 
HA 9 HOH   39  7339 14   HOH   HOH B . 
HA 9 HOH   40  7340 58   HOH   HOH B . 
HA 9 HOH   41  7341 7    HOH   HOH B . 
HA 9 HOH   42  7342 22   HOH   HOH B . 
HA 9 HOH   43  7343 12   HOH   HOH B . 
HA 9 HOH   44  7344 112  HOH   HOH B . 
HA 9 HOH   45  7345 265  HOH   HOH B . 
HA 9 HOH   46  7346 377  HOH   HOH B . 
HA 9 HOH   47  7347 9    HOH   HOH B . 
HA 9 HOH   48  7348 372  HOH   HOH B . 
HA 9 HOH   49  7349 74   HOH   HOH B . 
HA 9 HOH   50  7350 55   HOH   HOH B . 
HA 9 HOH   51  7351 183  HOH   HOH B . 
HA 9 HOH   52  7352 326  HOH   HOH B . 
HA 9 HOH   53  7353 65   HOH   HOH B . 
HA 9 HOH   54  7354 67   HOH   HOH B . 
HA 9 HOH   55  7355 374  HOH   HOH B . 
HA 9 HOH   56  7356 76   HOH   HOH B . 
HA 9 HOH   57  7357 72   HOH   HOH B . 
HA 9 HOH   58  7358 8    HOH   HOH B . 
HA 9 HOH   59  7359 71   HOH   HOH B . 
HA 9 HOH   60  7360 295  HOH   HOH B . 
HA 9 HOH   61  7361 30   HOH   HOH B . 
HA 9 HOH   62  7362 110  HOH   HOH B . 
HA 9 HOH   63  7363 2    HOH   HOH B . 
HA 9 HOH   64  7364 11   HOH   HOH B . 
HA 9 HOH   65  7365 132  HOH   HOH B . 
HA 9 HOH   66  7366 103  HOH   HOH B . 
HA 9 HOH   67  7367 19   HOH   HOH B . 
HA 9 HOH   68  7368 258  HOH   HOH B . 
HA 9 HOH   69  7369 188  HOH   HOH B . 
HA 9 HOH   70  7370 41   HOH   HOH B . 
HA 9 HOH   71  7371 190  HOH   HOH B . 
HA 9 HOH   72  7372 33   HOH   HOH B . 
HA 9 HOH   73  7373 227  HOH   HOH B . 
HA 9 HOH   74  7374 125  HOH   HOH B . 
HA 9 HOH   75  7375 272  HOH   HOH B . 
HA 9 HOH   76  7376 133  HOH   HOH B . 
HA 9 HOH   77  7377 264  HOH   HOH B . 
HA 9 HOH   78  7378 352  HOH   HOH B . 
HA 9 HOH   79  7379 206  HOH   HOH B . 
HA 9 HOH   80  7380 84   HOH   HOH B . 
HA 9 HOH   81  7381 323  HOH   HOH B . 
HA 9 HOH   82  7382 131  HOH   HOH B . 
HA 9 HOH   83  7383 40   HOH   HOH B . 
HA 9 HOH   84  7384 23   HOH   HOH B . 
HA 9 HOH   85  7385 373  HOH   HOH B . 
HA 9 HOH   86  7386 431  HOH   HOH B . 
HA 9 HOH   87  7387 293  HOH   HOH B . 
HA 9 HOH   88  7388 86   HOH   HOH B . 
HA 9 HOH   89  7389 200  HOH   HOH B . 
HA 9 HOH   90  7390 70   HOH   HOH B . 
HA 9 HOH   91  7391 50   HOH   HOH B . 
HA 9 HOH   92  7392 282  HOH   HOH B . 
HA 9 HOH   93  7393 149  HOH   HOH B . 
HA 9 HOH   94  7394 53   HOH   HOH B . 
HA 9 HOH   95  7395 16   HOH   HOH B . 
HA 9 HOH   96  7396 49   HOH   HOH B . 
HA 9 HOH   97  7397 313  HOH   HOH B . 
HA 9 HOH   98  7398 475  HOH   HOH B . 
HA 9 HOH   99  7399 178  HOH   HOH B . 
HA 9 HOH   100 7400 157  HOH   HOH B . 
HA 9 HOH   101 7401 174  HOH   HOH B . 
HA 9 HOH   102 7402 48   HOH   HOH B . 
HA 9 HOH   103 7403 153  HOH   HOH B . 
HA 9 HOH   104 7404 465  HOH   HOH B . 
HA 9 HOH   105 7405 167  HOH   HOH B . 
HA 9 HOH   106 7406 47   HOH   HOH B . 
HA 9 HOH   107 7407 459  HOH   HOH B . 
HA 9 HOH   108 7408 17   HOH   HOH B . 
HA 9 HOH   109 7409 179  HOH   HOH B . 
HA 9 HOH   110 7410 113  HOH   HOH B . 
HA 9 HOH   111 7411 332  HOH   HOH B . 
HA 9 HOH   112 7412 106  HOH   HOH B . 
HA 9 HOH   113 7413 244  HOH   HOH B . 
HA 9 HOH   114 7414 129  HOH   HOH B . 
HA 9 HOH   115 7415 246  HOH   HOH B . 
HA 9 HOH   116 7416 181  HOH   HOH B . 
HA 9 HOH   117 7417 322  HOH   HOH B . 
HA 9 HOH   118 7418 288  HOH   HOH B . 
HA 9 HOH   119 7419 45   HOH   HOH B . 
HA 9 HOH   120 7420 80   HOH   HOH B . 
HA 9 HOH   121 7421 159  HOH   HOH B . 
HA 9 HOH   122 7422 66   HOH   HOH B . 
HA 9 HOH   123 7423 52   HOH   HOH B . 
HA 9 HOH   124 7424 444  HOH   HOH B . 
HA 9 HOH   125 7425 3    HOH   HOH B . 
HA 9 HOH   126 7426 329  HOH   HOH B . 
HA 9 HOH   127 7427 453  HOH   HOH B . 
HA 9 HOH   128 7428 367  HOH   HOH B . 
HA 9 HOH   129 7429 471  HOH   HOH B . 
HA 9 HOH   130 7430 140  HOH   HOH B . 
HA 9 HOH   131 7431 104  HOH   HOH B . 
HA 9 HOH   132 7432 447  HOH   HOH B . 
HA 9 HOH   133 7433 139  HOH   HOH B . 
HA 9 HOH   134 7434 328  HOH   HOH B . 
HA 9 HOH   135 7435 242  HOH   HOH B . 
HA 9 HOH   136 7436 208  HOH   HOH B . 
HA 9 HOH   137 7437 38   HOH   HOH B . 
HA 9 HOH   138 7438 388  HOH   HOH B . 
HA 9 HOH   139 7439 450  HOH   HOH B . 
HA 9 HOH   140 7440 83   HOH   HOH B . 
HA 9 HOH   141 7441 169  HOH   HOH B . 
HA 9 HOH   142 7442 347  HOH   HOH B . 
HA 9 HOH   143 7443 278  HOH   HOH B . 
HA 9 HOH   144 7444 138  HOH   HOH B . 
HA 9 HOH   145 7445 199  HOH   HOH B . 
HA 9 HOH   146 7446 429  HOH   HOH B . 
HA 9 HOH   147 7447 225  HOH   HOH B . 
HA 9 HOH   148 7448 226  HOH   HOH B . 
HA 9 HOH   149 7449 383  HOH   HOH B . 
HA 9 HOH   150 7450 189  HOH   HOH B . 
HA 9 HOH   151 7451 461  HOH   HOH B . 
HA 9 HOH   152 7452 240  HOH   HOH B . 
HA 9 HOH   153 7453 236  HOH   HOH B . 
HA 9 HOH   154 7454 393  HOH   HOH B . 
HA 9 HOH   155 7455 425  HOH   HOH B . 
HA 9 HOH   156 7456 127  HOH   HOH B . 
HA 9 HOH   157 7457 302  HOH   HOH B . 
HA 9 HOH   158 7458 358  HOH   HOH B . 
HA 9 HOH   159 7459 15   HOH   HOH B . 
HA 9 HOH   160 7460 420  HOH   HOH B . 
HA 9 HOH   161 7461 369  HOH   HOH B . 
HA 9 HOH   162 7462 114  HOH   HOH B . 
HA 9 HOH   163 7463 348  HOH   HOH B . 
HA 9 HOH   164 7464 303  HOH   HOH B . 
HA 9 HOH   165 7465 361  HOH   HOH B . 
HA 9 HOH   166 7466 141  HOH   HOH B . 
HA 9 HOH   167 7467 187  HOH   HOH B . 
HA 9 HOH   168 7468 357  HOH   HOH B . 
HA 9 HOH   169 7469 173  HOH   HOH B . 
HA 9 HOH   170 7470 310  HOH   HOH B . 
HA 9 HOH   171 7471 34   HOH   HOH B . 
HA 9 HOH   172 7472 18   HOH   HOH B . 
HA 9 HOH   173 7473 448  HOH   HOH B . 
HA 9 HOH   174 7474 287  HOH   HOH B . 
HA 9 HOH   175 7475 245  HOH   HOH B . 
HA 9 HOH   176 7476 223  HOH   HOH B . 
HA 9 HOH   177 7477 483  HOH   HOH B . 
HA 9 HOH   178 7478 432  HOH   HOH B . 
HA 9 HOH   179 7479 392  HOH   HOH B . 
HA 9 HOH   180 7480 480  HOH   HOH B . 
HA 9 HOH   181 7481 89   HOH   HOH B . 
HA 9 HOH   182 7482 111  HOH   HOH B . 
HA 9 HOH   183 7483 26   HOH   HOH B . 
HA 9 HOH   184 7484 270  HOH   HOH B . 
HA 9 HOH   185 7485 327  HOH   HOH B . 
HA 9 HOH   186 7486 307  HOH   HOH B . 
HA 9 HOH   187 7487 380  HOH   HOH B . 
HA 9 HOH   188 7488 456  HOH   HOH B . 
HA 9 HOH   189 7489 370  HOH   HOH B . 
HA 9 HOH   190 7490 466  HOH   HOH B . 
HA 9 HOH   191 7491 81   HOH   HOH B . 
HA 9 HOH   192 7492 224  HOH   HOH B . 
HA 9 HOH   193 7493 389  HOH   HOH B . 
HA 9 HOH   194 7494 382  HOH   HOH B . 
HA 9 HOH   195 7495 458  HOH   HOH B . 
HA 9 HOH   196 7496 387  HOH   HOH B . 
HA 9 HOH   197 7497 212  HOH   HOH B . 
HA 9 HOH   198 7498 411  HOH   HOH B . 
HA 9 HOH   199 7499 368  HOH   HOH B . 
HA 9 HOH   200 7500 300  HOH   HOH B . 
HA 9 HOH   201 7501 299  HOH   HOH B . 
HA 9 HOH   202 7502 449  HOH   HOH B . 
HA 9 HOH   203 7503 359  HOH   HOH B . 
HA 9 HOH   204 7504 481  HOH   HOH B . 
HA 9 HOH   205 7505 385  HOH   HOH B . 
HA 9 HOH   206 7506 457  HOH   HOH B . 
HA 9 HOH   207 7507 470  HOH   HOH B . 
HA 9 HOH   208 7508 362  HOH   HOH B . 
HA 9 HOH   209 7509 203  HOH   HOH B . 
HA 9 HOH   210 7510 321  HOH   HOH B . 
HA 9 HOH   211 7511 87   HOH   HOH B . 
HA 9 HOH   212 7512 395  HOH   HOH B . 
HA 9 HOH   213 7513 454  HOH   HOH B . 
HA 9 HOH   214 7514 391  HOH   HOH B . 
HA 9 HOH   215 7515 455  HOH   HOH B . 
HA 9 HOH   216 7516 182  HOH   HOH B . 
HA 9 HOH   217 7517 476  HOH   HOH B . 
HA 9 HOH   218 7518 325  HOH   HOH B . 
HA 9 HOH   219 7519 408  HOH   HOH B . 
HA 9 HOH   220 7520 82   HOH   HOH B . 
HA 9 HOH   221 7521 312  HOH   HOH B . 
HA 9 HOH   222 7522 118  HOH   HOH B . 
HA 9 HOH   223 7523 184  HOH   HOH B . 
HA 9 HOH   224 7524 394  HOH   HOH B . 
IA 9 HOH   1   4501 422  HOH   HOH C . 
IA 9 HOH   2   4502 231  HOH   HOH C . 
IA 9 HOH   3   4503 346  HOH   HOH C . 
IA 9 HOH   4   4504 160  HOH   HOH C . 
IA 9 HOH   5   4505 294  HOH   HOH C . 
IA 9 HOH   6   4506 402  HOH   HOH C . 
IA 9 HOH   7   4507 75   HOH   HOH C . 
IA 9 HOH   8   4508 331  HOH   HOH C . 
IA 9 HOH   9   4509 68   HOH   HOH C . 
IA 9 HOH   10  4510 170  HOH   HOH C . 
IA 9 HOH   11  4511 130  HOH   HOH C . 
IA 9 HOH   12  4512 20   HOH   HOH C . 
IA 9 HOH   13  4513 13   HOH   HOH C . 
IA 9 HOH   14  4514 128  HOH   HOH C . 
IA 9 HOH   15  4515 92   HOH   HOH C . 
IA 9 HOH   16  4516 409  HOH   HOH C . 
IA 9 HOH   17  4517 10   HOH   HOH C . 
IA 9 HOH   18  4518 77   HOH   HOH C . 
IA 9 HOH   19  4519 334  HOH   HOH C . 
IA 9 HOH   20  4520 4    HOH   HOH C . 
IA 9 HOH   21  4521 79   HOH   HOH C . 
IA 9 HOH   22  4522 43   HOH   HOH C . 
IA 9 HOH   23  4523 25   HOH   HOH C . 
IA 9 HOH   24  4524 196  HOH   HOH C . 
IA 9 HOH   25  4525 207  HOH   HOH C . 
IA 9 HOH   26  4526 351  HOH   HOH C . 
IA 9 HOH   27  4527 195  HOH   HOH C . 
IA 9 HOH   28  4528 473  HOH   HOH C . 
IA 9 HOH   29  4529 107  HOH   HOH C . 
IA 9 HOH   30  4530 57   HOH   HOH C . 
IA 9 HOH   31  4531 441  HOH   HOH C . 
IA 9 HOH   32  4532 39   HOH   HOH C . 
IA 9 HOH   33  4533 117  HOH   HOH C . 
IA 9 HOH   34  4534 297  HOH   HOH C . 
IA 9 HOH   35  4535 198  HOH   HOH C . 
IA 9 HOH   36  4536 296  HOH   HOH C . 
IA 9 HOH   37  4537 350  HOH   HOH C . 
IA 9 HOH   38  4538 437  HOH   HOH C . 
IA 9 HOH   39  4539 99   HOH   HOH C . 
IA 9 HOH   40  4540 63   HOH   HOH C . 
IA 9 HOH   41  4541 64   HOH   HOH C . 
IA 9 HOH   42  4542 419  HOH   HOH C . 
IA 9 HOH   43  4543 155  HOH   HOH C . 
IA 9 HOH   44  4544 354  HOH   HOH C . 
IA 9 HOH   45  4545 171  HOH   HOH C . 
IA 9 HOH   46  4546 109  HOH   HOH C . 
IA 9 HOH   47  4547 177  HOH   HOH C . 
IA 9 HOH   48  4548 61   HOH   HOH C . 
IA 9 HOH   49  4549 338  HOH   HOH C . 
IA 9 HOH   50  4550 335  HOH   HOH C . 
IA 9 HOH   51  4551 344  HOH   HOH C . 
IA 9 HOH   52  4552 73   HOH   HOH C . 
IA 9 HOH   53  4553 474  HOH   HOH C . 
IA 9 HOH   54  4554 345  HOH   HOH C . 
IA 9 HOH   55  4555 168  HOH   HOH C . 
IA 9 HOH   56  4556 333  HOH   HOH C . 
IA 9 HOH   57  4557 283  HOH   HOH C . 
IA 9 HOH   58  4558 42   HOH   HOH C . 
IA 9 HOH   59  4559 472  HOH   HOH C . 
IA 9 HOH   60  4560 126  HOH   HOH C . 
IA 9 HOH   61  4561 341  HOH   HOH C . 
IA 9 HOH   62  4562 342  HOH   HOH C . 
IA 9 HOH   63  4563 375  HOH   HOH C . 
IA 9 HOH   64  4564 478  HOH   HOH C . 
IA 9 HOH   65  4565 209  HOH   HOH C . 
IA 9 HOH   66  4566 349  HOH   HOH C . 
IA 9 HOH   67  4567 442  HOH   HOH C . 
IA 9 HOH   68  4568 406  HOH   HOH C . 
IA 9 HOH   69  4569 95   HOH   HOH C . 
IA 9 HOH   70  4570 281  HOH   HOH C . 
IA 9 HOH   71  4571 364  HOH   HOH C . 
IA 9 HOH   72  4572 434  HOH   HOH C . 
IA 9 HOH   73  4573 105  HOH   HOH C . 
IA 9 HOH   74  4574 468  HOH   HOH C . 
IA 9 HOH   75  4575 337  HOH   HOH C . 
IA 9 HOH   76  4576 462  HOH   HOH C . 
IA 9 HOH   77  4577 403  HOH   HOH C . 
IA 9 HOH   78  4578 401  HOH   HOH C . 
IA 9 HOH   79  4579 451  HOH   HOH C . 
IA 9 HOH   80  4580 440  HOH   HOH C . 
IA 9 HOH   81  4581 463  HOH   HOH C . 
IA 9 HOH   82  4582 446  HOH   HOH C . 
IA 9 HOH   83  4583 479  HOH   HOH C . 
IA 9 HOH   84  4584 399  HOH   HOH C . 
IA 9 HOH   85  4585 396  HOH   HOH C . 
IA 9 HOH   86  4586 405  HOH   HOH C . 
IA 9 HOH   87  4587 376  HOH   HOH C . 
IA 9 HOH   88  4588 469  HOH   HOH C . 
IA 9 HOH   89  4589 93   HOH   HOH C . 
IA 9 HOH   90  4590 298  HOH   HOH C . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 N 1 B A1IOL 7219 ? C17 ? U A1IOL 1 C17 
2 1 N 1 B A1IOL 7219 ? C18 ? U A1IOL 1 C18 
3 1 N 1 B A1IOL 7219 ? O5  ? U A1IOL 1 O5  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? BUILT=20210205 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? BUILT=20210205 2 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.21-5207      3 
? 'model building' ? ? ? ? ? ? ? ? ? ? ? Coot   ? ? ? 0.9.8.93       4 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.21-5207      5 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9GUY 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     167.610 
_cell.length_a_esd                 ? 
_cell.length_b                     167.610 
_cell.length_b_esd                 ? 
_cell.length_c                     51.640 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9GUY 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                152 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 31 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9GUY 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             4.27 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          71.21 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '400 mM sodium fluoride, 100 mM 2-(N-morpholino)ethanesulfonic acid' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-08-28 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.033210 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PETRA III, DESY BEAMLINE P11' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.033210 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   P11 
_diffrn_source.pdbx_synchrotron_site       'PETRA III, DESY' 
# 
_reflns.B_iso_Wilson_estimate                          42.32 
_reflns.entry_id                                       9GUY 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.1 
_reflns.d_resolution_low                               43.96 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     47725 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           97.93 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                8.2 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          5.81 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.2887 
_reflns.pdbx_Rpim_I_all                                0.09953 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.991 
_reflns.pdbx_CC_star                                   0.998 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.2707 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.1 
_reflns_shell.d_res_low                                     2.175 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.49 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4740 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               8.3 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               2.825 
_reflns_shell.pdbx_Rpim_I_all                               0.9674 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.256 
_reflns_shell.pdbx_CC_star                                  0.638 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          97.57 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  2.652 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9GUY 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.1 
_refine.ls_d_res_low                             43.96 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     47716 
_refine.ls_number_reflns_R_free                  631 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    97.93 
_refine.ls_percent_reflns_R_free                 1.04 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2008 
_refine.ls_R_factor_R_free                       0.2130 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1840 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.11 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 40.58 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.25 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        3213 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         168 
_refine_hist.number_atoms_solvent             314 
_refine_hist.number_atoms_total               3695 
_refine_hist.d_res_high                       2.1 
_refine_hist.d_res_low                        43.96 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  ? 3501 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.187  ? 4720 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 11.026 ? 495  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.072  ? 519  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.010  ? 592  ? f_plane_restr      ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.1 
_refine_ls_shell.d_res_low                        2.175 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             4 
_refine_ls_shell.number_reflns_R_work             4738 
_refine_ls_shell.percent_reflns_obs               97.57 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.3534 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   ? 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.3837 
# 
_struct.entry_id                     9GUY 
_struct.title                        
'SARS-CoV-2 methyltransferase nsp10-16 in complex with SAM and theophylline derivative LAS 54571098' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9GUY 
_struct_keywords.text            'methyltransferase, complex, inhibitor, viral protein' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A  N N 1 ? 
B  N N 2 ? 
C  N N 3 ? 
D  N N 4 ? 
E  N N 3 ? 
F  N N 3 ? 
G  N N 3 ? 
H  N N 3 ? 
I  N N 3 ? 
J  N N 3 ? 
K  N N 3 ? 
L  N N 3 ? 
M  N N 3 ? 
N  N N 3 ? 
O  N N 3 ? 
P  N N 3 ? 
Q  N N 3 ? 
R  N N 3 ? 
S  N N 3 ? 
T  N N 3 ? 
U  N N 5 ? 
V  N N 6 ? 
W  N N 7 ? 
X  N N 7 ? 
Y  N N 3 ? 
Z  N N 3 ? 
AA N N 3 ? 
BA N N 3 ? 
CA N N 8 ? 
DA N N 8 ? 
EA N N 3 ? 
FA N N 7 ? 
GA N N 3 ? 
HA N N 9 ? 
IA N N 9 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP R1AB_SARS2 P0DTD1 ? 1 
;SSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAP
GTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQK
LALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLS
SYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVNN
;
6799 
2 UNP R1AB_SARS2 P0DTD1 ? 2 
;AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCH
IDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQ
;
4254 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9GUY B 1 ? 298 ? P0DTD1 6799 ? 7096 ? 6799 7096 
2 2 9GUY C 2 ? 140 ? P0DTD1 4254 ? 4392 ? 4254 4392 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9GUY GLU B 299 ? UNP P0DTD1 ? ? 'expression tag' 7097 1 
1 9GUY ASN B 300 ? UNP P0DTD1 ? ? 'expression tag' 7098 2 
1 9GUY LEU B 301 ? UNP P0DTD1 ? ? 'expression tag' 7099 3 
1 9GUY TYR B 302 ? UNP P0DTD1 ? ? 'expression tag' 7100 4 
1 9GUY PHE B 303 ? UNP P0DTD1 ? ? 'expression tag' 7101 5 
1 9GUY GLN B 304 ? UNP P0DTD1 ? ? 'expression tag' 7102 6 
2 9GUY GLY C 1   ? UNP P0DTD1 ? ? 'expression tag' 4253 7 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 7900  ? 
1 MORE         39    ? 
1 'SSA (A^2)'  18980 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,AA,BA,CA,DA,EA,FA,GA,HA,IA 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 1   ? GLN A 6   ? SER B 6799 GLN B 6804 5 ? 6  
HELX_P HELX_P2  AA2 PRO A 12  ? MET A 17  ? PRO B 6810 MET B 6815 1 ? 6  
HELX_P HELX_P3  AA3 MET A 41  ? ASN A 55  ? MET B 6839 ASN B 6853 1 ? 15 
HELX_P HELX_P4  AA4 ALA A 79  ? LEU A 89  ? ALA B 6877 LEU B 6887 1 ? 11 
HELX_P HELX_P5  AA5 ASP A 114 ? ALA A 116 ? ASP B 6912 ALA B 6914 5 ? 3  
HELX_P HELX_P6  AA6 ASP A 133 ? LYS A 137 ? ASP B 6931 LYS B 6935 5 ? 5  
HELX_P HELX_P7  AA7 GLY A 148 ? LYS A 160 ? GLY B 6946 LYS B 6958 1 ? 13 
HELX_P HELX_P8  AA8 ASN A 177 ? GLY A 185 ? ASN B 6975 GLY B 6983 1 ? 9  
HELX_P HELX_P9  AA9 VAL A 197 ? ALA A 199 ? VAL B 6995 ALA B 6997 5 ? 3  
HELX_P HELX_P10 AB1 ASP A 220 ? ASN A 235 ? ASP B 7018 ASN B 7033 1 ? 16 
HELX_P HELX_P11 AB2 SER A 241 ? ASP A 246 ? SER B 7039 ASP B 7044 5 ? 6  
HELX_P HELX_P12 AB3 LYS A 263 ? ILE A 267 ? LYS B 7061 ILE B 7065 5 ? 5  
HELX_P HELX_P13 AB4 ASN A 268 ? LYS A 277 ? ASN B 7066 LYS B 7075 1 ? 10 
HELX_P HELX_P14 AB5 ASP B 23  ? SER B 34  ? ASP C 4275 SER C 4286 1 ? 12 
HELX_P HELX_P15 AB6 ALA B 72  ? CYS B 74  ? ALA C 4324 CYS C 4326 5 ? 3  
HELX_P HELX_P16 AB7 CYS B 75  ? HIS B 81  ? CYS C 4327 HIS C 4333 1 ? 7  
HELX_P HELX_P17 AB8 THR B 103 ? ALA B 105 ? THR C 4355 ALA C 4357 5 ? 3  
HELX_P HELX_P18 AB9 ASP B 107 ? ASN B 115 ? ASP C 4359 ASN C 4367 1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? B CYS 75  SG  ? ? ? 1_555 CA ZN . ZN ? ? C CYS 4327 C ZN 4401 1_555 ? ? ? ? ? ? ? 2.274 ? ? 
metalc2 metalc ? ? B CYS 78  SG  ? ? ? 1_555 CA ZN . ZN ? ? C CYS 4330 C ZN 4401 1_555 ? ? ? ? ? ? ? 2.297 ? ? 
metalc3 metalc ? ? B HIS 84  NE2 ? ? ? 1_555 CA ZN . ZN ? ? C HIS 4336 C ZN 4401 1_555 ? ? ? ? ? ? ? 2.067 ? ? 
metalc4 metalc ? ? B CYS 91  SG  ? ? ? 1_555 CA ZN . ZN ? ? C CYS 4343 C ZN 4401 1_555 ? ? ? ? ? ? ? 2.278 ? ? 
metalc5 metalc ? ? B CYS 118 SG  ? ? ? 1_555 DA ZN . ZN ? ? C CYS 4370 C ZN 4402 1_555 ? ? ? ? ? ? ? 2.311 ? ? 
metalc6 metalc ? ? B CYS 121 SG  ? ? ? 1_555 DA ZN . ZN ? ? C CYS 4373 C ZN 4402 1_555 ? ? ? ? ? ? ? 2.334 ? ? 
metalc7 metalc ? ? B CYS 129 SG  ? ? ? 1_555 DA ZN . ZN ? ? C CYS 4381 C ZN 4402 1_555 ? ? ? ? ? ? ? 2.332 ? ? 
metalc8 metalc ? ? B CYS 131 SG  ? ? ? 1_555 DA ZN . ZN ? ? C CYS 4383 C ZN 4402 1_555 ? ? ? ? ? ? ? 2.322 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  SG  ? B CYS 75  ? C CYS 4327 ? 1_555 ZN ? CA ZN . ? C ZN 4401 ? 1_555 SG  ? B CYS 78  ? C CYS 4330 ? 1_555 115.7 ? 
2  SG  ? B CYS 75  ? C CYS 4327 ? 1_555 ZN ? CA ZN . ? C ZN 4401 ? 1_555 NE2 ? B HIS 84  ? C HIS 4336 ? 1_555 105.9 ? 
3  SG  ? B CYS 78  ? C CYS 4330 ? 1_555 ZN ? CA ZN . ? C ZN 4401 ? 1_555 NE2 ? B HIS 84  ? C HIS 4336 ? 1_555 111.1 ? 
4  SG  ? B CYS 75  ? C CYS 4327 ? 1_555 ZN ? CA ZN . ? C ZN 4401 ? 1_555 SG  ? B CYS 91  ? C CYS 4343 ? 1_555 110.1 ? 
5  SG  ? B CYS 78  ? C CYS 4330 ? 1_555 ZN ? CA ZN . ? C ZN 4401 ? 1_555 SG  ? B CYS 91  ? C CYS 4343 ? 1_555 114.3 ? 
6  NE2 ? B HIS 84  ? C HIS 4336 ? 1_555 ZN ? CA ZN . ? C ZN 4401 ? 1_555 SG  ? B CYS 91  ? C CYS 4343 ? 1_555 98.0  ? 
7  SG  ? B CYS 118 ? C CYS 4370 ? 1_555 ZN ? DA ZN . ? C ZN 4402 ? 1_555 SG  ? B CYS 121 ? C CYS 4373 ? 1_555 107.1 ? 
8  SG  ? B CYS 118 ? C CYS 4370 ? 1_555 ZN ? DA ZN . ? C ZN 4402 ? 1_555 SG  ? B CYS 129 ? C CYS 4381 ? 1_555 108.5 ? 
9  SG  ? B CYS 121 ? C CYS 4373 ? 1_555 ZN ? DA ZN . ? C ZN 4402 ? 1_555 SG  ? B CYS 129 ? C CYS 4381 ? 1_555 111.6 ? 
10 SG  ? B CYS 118 ? C CYS 4370 ? 1_555 ZN ? DA ZN . ? C ZN 4402 ? 1_555 SG  ? B CYS 131 ? C CYS 4383 ? 1_555 107.6 ? 
11 SG  ? B CYS 121 ? C CYS 4373 ? 1_555 ZN ? DA ZN . ? C ZN 4402 ? 1_555 SG  ? B CYS 131 ? C CYS 4383 ? 1_555 107.8 ? 
12 SG  ? B CYS 129 ? C CYS 4381 ? 1_555 ZN ? DA ZN . ? C ZN 4402 ? 1_555 SG  ? B CYS 131 ? C CYS 4383 ? 1_555 113.9 ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 8 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA1 7 8 ? parallel      
AA2 1 2 ? anti-parallel 
AA3 1 2 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLY A 8   ? ALA A 10  ? GLY B 6806 ALA B 6808 
AA1 2 PHE A 187 ? THR A 195 ? PHE B 6985 THR B 6993 
AA1 3 ALA A 204 ? TYR A 211 ? ALA B 7002 TYR B 7009 
AA1 4 LEU A 161 ? ILE A 171 ? LEU B 6959 ILE B 6969 
AA1 5 TRP A 124 ? SER A 129 ? TRP B 6922 SER B 6927 
AA1 6 ARG A 66  ? PHE A 70  ? ARG B 6864 PHE B 6868 
AA1 7 LEU A 94  ? ASP A 99  ? LEU B 6892 ASP B 6897 
AA1 8 SER A 109 ? ILE A 112 ? SER B 6907 ILE B 6910 
AA2 1 VAL A 118 ? THR A 120 ? VAL B 6916 THR B 6918 
AA2 2 ILE A 290 ? SER A 292 ? ILE B 7088 SER B 7090 
AA3 1 ALA A 258 ? MET A 260 ? ALA B 7056 MET B 7058 
AA3 2 LEU A 280 ? ILE A 282 ? LEU B 7078 ILE B 7080 
AA4 1 ILE B 56  ? THR B 57  ? ILE C 4308 THR C 4309 
AA4 2 TYR B 97  ? PRO B 101 ? TYR C 4349 PRO C 4353 
AA4 3 GLN B 66  ? GLY B 70  ? GLN C 4318 GLY C 4322 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 9   ? N VAL B 6807 O VAL A 194 ? O VAL B 6992 
AA1 2 3 N TRP A 189 ? N TRP B 6987 O CYS A 209 ? O CYS B 7007 
AA1 3 4 O ALA A 204 ? O ALA B 7002 N ILE A 171 ? N ILE B 6969 
AA1 4 5 O ALA A 162 ? O ALA B 6960 N TRP A 124 ? N TRP B 6922 
AA1 5 6 O ILE A 128 ? O ILE B 6926 N PHE A 70  ? N PHE B 6868 
AA1 6 7 N VAL A 67  ? N VAL B 6865 O LEU A 94  ? O LEU B 6892 
AA1 7 8 N ASP A 97  ? N ASP B 6895 O LEU A 111 ? O LEU B 6909 
AA2 1 2 N HIS A 119 ? N HIS B 6917 O SER A 291 ? O SER B 7089 
AA3 1 2 N ALA A 258 ? N ALA B 7056 O ILE A 281 ? O ILE B 7079 
AA4 1 2 N THR B 57  ? N THR C 4309 O TYR B 97  ? O TYR C 4349 
AA4 2 3 O ILE B 100 ? O ILE C 4352 N GLU B 67  ? N GLU C 4319 
# 
_pdbx_entry_details.entry_id                   9GUY 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 HH22 B ARG 7014 ? ? OE1 B GLU 7015 ? ? 1.55 
2 1 O    B HOH 7439 ? ? O   B HOH 7502 ? ? 2.02 
3 1 O    B LEU 6887 ? ? O   B HOH 7301 ? ? 2.12 
4 1 O    C HOH 4531 ? ? O   C HOH 4578 ? ? 2.12 
5 1 OG   C SER 4286 ? ? O   C HOH 4501 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER B 6800 ? ? -58.57  -5.83   
2  1 THR B 6856 ? ? -95.64  59.33   
3  1 ASP B 6873 ? ? -69.79  0.27    
4  1 LYS B 6935 ? ? -78.88  41.26   
5  1 GLU B 6945 ? ? -106.65 -110.20 
6  1 ASN B 7008 ? ? 70.13   95.77   
7  1 ASN B 7066 ? ? -103.02 -154.29 
8  1 ASN B 7084 ? ? -74.32  -167.67 
9  1 ASN C 4315 ? ? -100.16 -166.11 
10 1 LYS C 4348 ? ? -125.25 -169.20 
11 1 ASP C 4384 ? ? -100.10 58.71   
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    B 
_pdbx_validate_planes.auth_seq_id     7085 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.076 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      B 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       7524 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.82 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 B TYR 7100 ? A TYR 302 
2  1 Y 1 B PHE 7101 ? A PHE 303 
3  1 Y 1 B GLN 7102 ? A GLN 304 
4  1 Y 1 C GLY 4253 ? B GLY 1   
5  1 Y 1 C ALA 4254 ? B ALA 2   
6  1 Y 1 C GLY 4255 ? B GLY 3   
7  1 Y 1 C ASN 4256 ? B ASN 4   
8  1 Y 1 C ALA 4257 ? B ALA 5   
9  1 Y 1 C THR 4258 ? B THR 6   
10 1 Y 1 C GLU 4259 ? B GLU 7   
11 1 Y 1 C VAL 4260 ? B VAL 8   
12 1 Y 1 C PRO 4261 ? B PRO 9   
13 1 Y 1 C ALA 4262 ? B ALA 10  
14 1 Y 1 C ASN 4263 ? B ASN 11  
15 1 Y 1 C SER 4264 ? B SER 12  
16 1 Y 1 C THR 4265 ? B THR 13  
17 1 Y 1 C VAL 4266 ? B VAL 14  
18 1 Y 1 C LEU 4267 ? B LEU 15  
19 1 Y 1 C SER 4268 ? B SER 16  
20 1 Y 1 C PHE 4269 ? B PHE 17  
21 1 Y 1 C CYS 4270 ? B CYS 18  
22 1 Y 1 C LEU 4386 ? B LEU 134 
23 1 Y 1 C ARG 4387 ? B ARG 135 
24 1 Y 1 C GLU 4388 ? B GLU 136 
25 1 Y 1 C PRO 4389 ? B PRO 137 
26 1 Y 1 C MET 4390 ? B MET 138 
27 1 Y 1 C LEU 4391 ? B LEU 139 
28 1 Y 1 C GLN 4392 ? B GLN 140 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1IOL N1     N  Y N 1   
A1IOL N3     N  N N 2   
A1IOL C4     C  Y N 3   
A1IOL C5     C  N N 4   
A1IOL C6     C  N S 5   
A1IOL C7     C  N S 6   
A1IOL C8     C  N N 7   
A1IOL C10    C  N N 8   
A1IOL C13    C  N N 9   
A1IOL C15    C  N N 10  
A1IOL C17    C  N N 11  
A1IOL C20    C  N N 12  
A1IOL C21    C  N N 13  
A1IOL N      N  N N 14  
A1IOL C      C  N N 15  
A1IOL O      O  N N 16  
A1IOL C1     C  N N 17  
A1IOL C11    C  N N 18  
A1IOL C12    C  N S 19  
A1IOL C14    C  N N 20  
A1IOL C16    C  N N 21  
A1IOL C18    C  N N 22  
A1IOL C19    C  N N 23  
A1IOL C2     C  Y N 24  
A1IOL C3     C  Y N 25  
A1IOL C9     C  N R 26  
A1IOL N2     N  Y N 27  
A1IOL N4     N  N N 28  
A1IOL N5     N  N N 29  
A1IOL N6     N  N N 30  
A1IOL O1     O  N N 31  
A1IOL O2     O  N N 32  
A1IOL O3     O  N N 33  
A1IOL O4     O  N N 34  
A1IOL O5     O  N N 35  
A1IOL H4     H  N N 36  
A1IOL H6     H  N N 37  
A1IOL H5     H  N N 38  
A1IOL H      H  N N 39  
A1IOL H9     H  N N 40  
A1IOL H8     H  N N 41  
A1IOL H12    H  N N 42  
A1IOL H11    H  N N 43  
A1IOL H15    H  N N 44  
A1IOL H16    H  N N 45  
A1IOL H19    H  N N 46  
A1IOL H20    H  N N 47  
A1IOL H29    H  N N 48  
A1IOL H31    H  N N 49  
A1IOL H30    H  N N 50  
A1IOL H32    H  N N 51  
A1IOL H33    H  N N 52  
A1IOL H34    H  N N 53  
A1IOL H2     H  N N 54  
A1IOL H18    H  N N 55  
A1IOL H17    H  N N 56  
A1IOL H22    H  N N 57  
A1IOL H21    H  N N 58  
A1IOL H26    H  N N 59  
A1IOL H24    H  N N 60  
A1IOL H25    H  N N 61  
A1IOL H27    H  N N 62  
A1IOL H28    H  N N 63  
A1IOL H3     H  N N 64  
A1IOL H1     H  N N 65  
A1IOL H13    H  N N 66  
A1IOL H35    H  N N 67  
A1IOL H23    H  N N 68  
A1IOL H7     H  N N 69  
A1IOL H10    H  N N 70  
ALA   N      N  N N 71  
ALA   CA     C  N S 72  
ALA   C      C  N N 73  
ALA   O      O  N N 74  
ALA   CB     C  N N 75  
ALA   OXT    O  N N 76  
ALA   H      H  N N 77  
ALA   H2     H  N N 78  
ALA   HA     H  N N 79  
ALA   HB1    H  N N 80  
ALA   HB2    H  N N 81  
ALA   HB3    H  N N 82  
ALA   HXT    H  N N 83  
ARG   N      N  N N 84  
ARG   CA     C  N S 85  
ARG   C      C  N N 86  
ARG   O      O  N N 87  
ARG   CB     C  N N 88  
ARG   CG     C  N N 89  
ARG   CD     C  N N 90  
ARG   NE     N  N N 91  
ARG   CZ     C  N N 92  
ARG   NH1    N  N N 93  
ARG   NH2    N  N N 94  
ARG   OXT    O  N N 95  
ARG   H      H  N N 96  
ARG   H2     H  N N 97  
ARG   HA     H  N N 98  
ARG   HB2    H  N N 99  
ARG   HB3    H  N N 100 
ARG   HG2    H  N N 101 
ARG   HG3    H  N N 102 
ARG   HD2    H  N N 103 
ARG   HD3    H  N N 104 
ARG   HE     H  N N 105 
ARG   HH11   H  N N 106 
ARG   HH12   H  N N 107 
ARG   HH21   H  N N 108 
ARG   HH22   H  N N 109 
ARG   HXT    H  N N 110 
ASN   N      N  N N 111 
ASN   CA     C  N S 112 
ASN   C      C  N N 113 
ASN   O      O  N N 114 
ASN   CB     C  N N 115 
ASN   CG     C  N N 116 
ASN   OD1    O  N N 117 
ASN   ND2    N  N N 118 
ASN   OXT    O  N N 119 
ASN   H      H  N N 120 
ASN   H2     H  N N 121 
ASN   HA     H  N N 122 
ASN   HB2    H  N N 123 
ASN   HB3    H  N N 124 
ASN   HD21   H  N N 125 
ASN   HD22   H  N N 126 
ASN   HXT    H  N N 127 
ASP   N      N  N N 128 
ASP   CA     C  N S 129 
ASP   C      C  N N 130 
ASP   O      O  N N 131 
ASP   CB     C  N N 132 
ASP   CG     C  N N 133 
ASP   OD1    O  N N 134 
ASP   OD2    O  N N 135 
ASP   OXT    O  N N 136 
ASP   H      H  N N 137 
ASP   H2     H  N N 138 
ASP   HA     H  N N 139 
ASP   HB2    H  N N 140 
ASP   HB3    H  N N 141 
ASP   HD2    H  N N 142 
ASP   HXT    H  N N 143 
CL    CL     CL N N 144 
CYS   N      N  N N 145 
CYS   CA     C  N R 146 
CYS   C      C  N N 147 
CYS   O      O  N N 148 
CYS   CB     C  N N 149 
CYS   SG     S  N N 150 
CYS   OXT    O  N N 151 
CYS   H      H  N N 152 
CYS   H2     H  N N 153 
CYS   HA     H  N N 154 
CYS   HB2    H  N N 155 
CYS   HB3    H  N N 156 
CYS   HG     H  N N 157 
CYS   HXT    H  N N 158 
EDO   C1     C  N N 159 
EDO   O1     O  N N 160 
EDO   C2     C  N N 161 
EDO   O2     O  N N 162 
EDO   H11    H  N N 163 
EDO   H12    H  N N 164 
EDO   HO1    H  N N 165 
EDO   H21    H  N N 166 
EDO   H22    H  N N 167 
EDO   HO2    H  N N 168 
GLN   N      N  N N 169 
GLN   CA     C  N S 170 
GLN   C      C  N N 171 
GLN   O      O  N N 172 
GLN   CB     C  N N 173 
GLN   CG     C  N N 174 
GLN   CD     C  N N 175 
GLN   OE1    O  N N 176 
GLN   NE2    N  N N 177 
GLN   OXT    O  N N 178 
GLN   H      H  N N 179 
GLN   H2     H  N N 180 
GLN   HA     H  N N 181 
GLN   HB2    H  N N 182 
GLN   HB3    H  N N 183 
GLN   HG2    H  N N 184 
GLN   HG3    H  N N 185 
GLN   HE21   H  N N 186 
GLN   HE22   H  N N 187 
GLN   HXT    H  N N 188 
GLU   N      N  N N 189 
GLU   CA     C  N S 190 
GLU   C      C  N N 191 
GLU   O      O  N N 192 
GLU   CB     C  N N 193 
GLU   CG     C  N N 194 
GLU   CD     C  N N 195 
GLU   OE1    O  N N 196 
GLU   OE2    O  N N 197 
GLU   OXT    O  N N 198 
GLU   H      H  N N 199 
GLU   H2     H  N N 200 
GLU   HA     H  N N 201 
GLU   HB2    H  N N 202 
GLU   HB3    H  N N 203 
GLU   HG2    H  N N 204 
GLU   HG3    H  N N 205 
GLU   HE2    H  N N 206 
GLU   HXT    H  N N 207 
GLY   N      N  N N 208 
GLY   CA     C  N N 209 
GLY   C      C  N N 210 
GLY   O      O  N N 211 
GLY   OXT    O  N N 212 
GLY   H      H  N N 213 
GLY   H2     H  N N 214 
GLY   HA2    H  N N 215 
GLY   HA3    H  N N 216 
GLY   HXT    H  N N 217 
HIS   N      N  N N 218 
HIS   CA     C  N S 219 
HIS   C      C  N N 220 
HIS   O      O  N N 221 
HIS   CB     C  N N 222 
HIS   CG     C  Y N 223 
HIS   ND1    N  Y N 224 
HIS   CD2    C  Y N 225 
HIS   CE1    C  Y N 226 
HIS   NE2    N  Y N 227 
HIS   OXT    O  N N 228 
HIS   H      H  N N 229 
HIS   H2     H  N N 230 
HIS   HA     H  N N 231 
HIS   HB2    H  N N 232 
HIS   HB3    H  N N 233 
HIS   HD1    H  N N 234 
HIS   HD2    H  N N 235 
HIS   HE1    H  N N 236 
HIS   HE2    H  N N 237 
HIS   HXT    H  N N 238 
HOH   O      O  N N 239 
HOH   H1     H  N N 240 
HOH   H2     H  N N 241 
ILE   N      N  N N 242 
ILE   CA     C  N S 243 
ILE   C      C  N N 244 
ILE   O      O  N N 245 
ILE   CB     C  N S 246 
ILE   CG1    C  N N 247 
ILE   CG2    C  N N 248 
ILE   CD1    C  N N 249 
ILE   OXT    O  N N 250 
ILE   H      H  N N 251 
ILE   H2     H  N N 252 
ILE   HA     H  N N 253 
ILE   HB     H  N N 254 
ILE   HG12   H  N N 255 
ILE   HG13   H  N N 256 
ILE   HG21   H  N N 257 
ILE   HG22   H  N N 258 
ILE   HG23   H  N N 259 
ILE   HD11   H  N N 260 
ILE   HD12   H  N N 261 
ILE   HD13   H  N N 262 
ILE   HXT    H  N N 263 
LEU   N      N  N N 264 
LEU   CA     C  N S 265 
LEU   C      C  N N 266 
LEU   O      O  N N 267 
LEU   CB     C  N N 268 
LEU   CG     C  N N 269 
LEU   CD1    C  N N 270 
LEU   CD2    C  N N 271 
LEU   OXT    O  N N 272 
LEU   H      H  N N 273 
LEU   H2     H  N N 274 
LEU   HA     H  N N 275 
LEU   HB2    H  N N 276 
LEU   HB3    H  N N 277 
LEU   HG     H  N N 278 
LEU   HD11   H  N N 279 
LEU   HD12   H  N N 280 
LEU   HD13   H  N N 281 
LEU   HD21   H  N N 282 
LEU   HD22   H  N N 283 
LEU   HD23   H  N N 284 
LEU   HXT    H  N N 285 
LYS   N      N  N N 286 
LYS   CA     C  N S 287 
LYS   C      C  N N 288 
LYS   O      O  N N 289 
LYS   CB     C  N N 290 
LYS   CG     C  N N 291 
LYS   CD     C  N N 292 
LYS   CE     C  N N 293 
LYS   NZ     N  N N 294 
LYS   OXT    O  N N 295 
LYS   H      H  N N 296 
LYS   H2     H  N N 297 
LYS   HA     H  N N 298 
LYS   HB2    H  N N 299 
LYS   HB3    H  N N 300 
LYS   HG2    H  N N 301 
LYS   HG3    H  N N 302 
LYS   HD2    H  N N 303 
LYS   HD3    H  N N 304 
LYS   HE2    H  N N 305 
LYS   HE3    H  N N 306 
LYS   HZ1    H  N N 307 
LYS   HZ2    H  N N 308 
LYS   HZ3    H  N N 309 
LYS   HXT    H  N N 310 
MES   O1     O  N N 311 
MES   C2     C  N N 312 
MES   C3     C  N N 313 
MES   N4     N  N N 314 
MES   C5     C  N N 315 
MES   C6     C  N N 316 
MES   C7     C  N N 317 
MES   C8     C  N N 318 
MES   S      S  N N 319 
MES   O1S    O  N N 320 
MES   O2S    O  N N 321 
MES   O3S    O  N N 322 
MES   H21    H  N N 323 
MES   H22    H  N N 324 
MES   H31    H  N N 325 
MES   H32    H  N N 326 
MES   HN4    H  N N 327 
MES   H51    H  N N 328 
MES   H52    H  N N 329 
MES   H61    H  N N 330 
MES   H62    H  N N 331 
MES   H71    H  N N 332 
MES   H72    H  N N 333 
MES   H81    H  N N 334 
MES   H82    H  N N 335 
MET   N      N  N N 336 
MET   CA     C  N S 337 
MET   C      C  N N 338 
MET   O      O  N N 339 
MET   CB     C  N N 340 
MET   CG     C  N N 341 
MET   SD     S  N N 342 
MET   CE     C  N N 343 
MET   OXT    O  N N 344 
MET   H      H  N N 345 
MET   H2     H  N N 346 
MET   HA     H  N N 347 
MET   HB2    H  N N 348 
MET   HB3    H  N N 349 
MET   HG2    H  N N 350 
MET   HG3    H  N N 351 
MET   HE1    H  N N 352 
MET   HE2    H  N N 353 
MET   HE3    H  N N 354 
MET   HXT    H  N N 355 
PHE   N      N  N N 356 
PHE   CA     C  N S 357 
PHE   C      C  N N 358 
PHE   O      O  N N 359 
PHE   CB     C  N N 360 
PHE   CG     C  Y N 361 
PHE   CD1    C  Y N 362 
PHE   CD2    C  Y N 363 
PHE   CE1    C  Y N 364 
PHE   CE2    C  Y N 365 
PHE   CZ     C  Y N 366 
PHE   OXT    O  N N 367 
PHE   H      H  N N 368 
PHE   H2     H  N N 369 
PHE   HA     H  N N 370 
PHE   HB2    H  N N 371 
PHE   HB3    H  N N 372 
PHE   HD1    H  N N 373 
PHE   HD2    H  N N 374 
PHE   HE1    H  N N 375 
PHE   HE2    H  N N 376 
PHE   HZ     H  N N 377 
PHE   HXT    H  N N 378 
PRO   N      N  N N 379 
PRO   CA     C  N S 380 
PRO   C      C  N N 381 
PRO   O      O  N N 382 
PRO   CB     C  N N 383 
PRO   CG     C  N N 384 
PRO   CD     C  N N 385 
PRO   OXT    O  N N 386 
PRO   H      H  N N 387 
PRO   HA     H  N N 388 
PRO   HB2    H  N N 389 
PRO   HB3    H  N N 390 
PRO   HG2    H  N N 391 
PRO   HG3    H  N N 392 
PRO   HD2    H  N N 393 
PRO   HD3    H  N N 394 
PRO   HXT    H  N N 395 
SAM   N      N  N N 396 
SAM   CA     C  N S 397 
SAM   C      C  N N 398 
SAM   O      O  N N 399 
SAM   OXT    O  N N 400 
SAM   CB     C  N N 401 
SAM   CG     C  N N 402 
SAM   SD     S  N S 403 
SAM   CE     C  N N 404 
SAM   "C5'"  C  N N 405 
SAM   "C4'"  C  N S 406 
SAM   "O4'"  O  N N 407 
SAM   "C3'"  C  N S 408 
SAM   "O3'"  O  N N 409 
SAM   "C2'"  C  N R 410 
SAM   "O2'"  O  N N 411 
SAM   "C1'"  C  N R 412 
SAM   N9     N  Y N 413 
SAM   C8     C  Y N 414 
SAM   N7     N  Y N 415 
SAM   C5     C  Y N 416 
SAM   C6     C  Y N 417 
SAM   N6     N  N N 418 
SAM   N1     N  Y N 419 
SAM   C2     C  Y N 420 
SAM   N3     N  Y N 421 
SAM   C4     C  Y N 422 
SAM   HN1    H  N N 423 
SAM   HN2    H  N N 424 
SAM   HA     H  N N 425 
SAM   HB1    H  N N 426 
SAM   HB2    H  N N 427 
SAM   HG1    H  N N 428 
SAM   HG2    H  N N 429 
SAM   HE1    H  N N 430 
SAM   HE2    H  N N 431 
SAM   HE3    H  N N 432 
SAM   "H5'1" H  N N 433 
SAM   "H5'2" H  N N 434 
SAM   "H4'"  H  N N 435 
SAM   "H3'"  H  N N 436 
SAM   "HO3'" H  N N 437 
SAM   "H2'"  H  N N 438 
SAM   "HO2'" H  N N 439 
SAM   "H1'"  H  N N 440 
SAM   H8     H  N N 441 
SAM   HN61   H  N N 442 
SAM   HN62   H  N N 443 
SAM   H2     H  N N 444 
SER   N      N  N N 445 
SER   CA     C  N S 446 
SER   C      C  N N 447 
SER   O      O  N N 448 
SER   CB     C  N N 449 
SER   OG     O  N N 450 
SER   OXT    O  N N 451 
SER   H      H  N N 452 
SER   H2     H  N N 453 
SER   HA     H  N N 454 
SER   HB2    H  N N 455 
SER   HB3    H  N N 456 
SER   HG     H  N N 457 
SER   HXT    H  N N 458 
THR   N      N  N N 459 
THR   CA     C  N S 460 
THR   C      C  N N 461 
THR   O      O  N N 462 
THR   CB     C  N R 463 
THR   OG1    O  N N 464 
THR   CG2    C  N N 465 
THR   OXT    O  N N 466 
THR   H      H  N N 467 
THR   H2     H  N N 468 
THR   HA     H  N N 469 
THR   HB     H  N N 470 
THR   HG1    H  N N 471 
THR   HG21   H  N N 472 
THR   HG22   H  N N 473 
THR   HG23   H  N N 474 
THR   HXT    H  N N 475 
TRP   N      N  N N 476 
TRP   CA     C  N S 477 
TRP   C      C  N N 478 
TRP   O      O  N N 479 
TRP   CB     C  N N 480 
TRP   CG     C  Y N 481 
TRP   CD1    C  Y N 482 
TRP   CD2    C  Y N 483 
TRP   NE1    N  Y N 484 
TRP   CE2    C  Y N 485 
TRP   CE3    C  Y N 486 
TRP   CZ2    C  Y N 487 
TRP   CZ3    C  Y N 488 
TRP   CH2    C  Y N 489 
TRP   OXT    O  N N 490 
TRP   H      H  N N 491 
TRP   H2     H  N N 492 
TRP   HA     H  N N 493 
TRP   HB2    H  N N 494 
TRP   HB3    H  N N 495 
TRP   HD1    H  N N 496 
TRP   HE1    H  N N 497 
TRP   HE3    H  N N 498 
TRP   HZ2    H  N N 499 
TRP   HZ3    H  N N 500 
TRP   HH2    H  N N 501 
TRP   HXT    H  N N 502 
TYR   N      N  N N 503 
TYR   CA     C  N S 504 
TYR   C      C  N N 505 
TYR   O      O  N N 506 
TYR   CB     C  N N 507 
TYR   CG     C  Y N 508 
TYR   CD1    C  Y N 509 
TYR   CD2    C  Y N 510 
TYR   CE1    C  Y N 511 
TYR   CE2    C  Y N 512 
TYR   CZ     C  Y N 513 
TYR   OH     O  N N 514 
TYR   OXT    O  N N 515 
TYR   H      H  N N 516 
TYR   H2     H  N N 517 
TYR   HA     H  N N 518 
TYR   HB2    H  N N 519 
TYR   HB3    H  N N 520 
TYR   HD1    H  N N 521 
TYR   HD2    H  N N 522 
TYR   HE1    H  N N 523 
TYR   HE2    H  N N 524 
TYR   HH     H  N N 525 
TYR   HXT    H  N N 526 
VAL   N      N  N N 527 
VAL   CA     C  N S 528 
VAL   C      C  N N 529 
VAL   O      O  N N 530 
VAL   CB     C  N N 531 
VAL   CG1    C  N N 532 
VAL   CG2    C  N N 533 
VAL   OXT    O  N N 534 
VAL   H      H  N N 535 
VAL   H2     H  N N 536 
VAL   HA     H  N N 537 
VAL   HB     H  N N 538 
VAL   HG11   H  N N 539 
VAL   HG12   H  N N 540 
VAL   HG13   H  N N 541 
VAL   HG21   H  N N 542 
VAL   HG22   H  N N 543 
VAL   HG23   H  N N 544 
VAL   HXT    H  N N 545 
ZN    ZN     ZN N N 546 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1IOL C5    N3     sing N N 1   
A1IOL O     C      doub N N 2   
A1IOL N3    C      sing N N 3   
A1IOL N3    C4     sing N N 4   
A1IOL C     N      sing N N 5   
A1IOL N2    C4     sing Y N 6   
A1IOL N2    C3     doub Y N 7   
A1IOL C4    C2     doub Y N 8   
A1IOL N     C21    sing N N 9   
A1IOL N     C1     sing N N 10  
A1IOL C3    N1     sing Y N 11  
A1IOL C2    C1     sing N N 12  
A1IOL C2    N1     sing Y N 13  
A1IOL C1    O1     doub N N 14  
A1IOL N1    C6     sing N N 15  
A1IOL N5    C12    sing N N 16  
A1IOL O4    C11    doub N N 17  
A1IOL C12   C11    sing N N 18  
A1IOL C12   C13    sing N N 19  
A1IOL C11   N4     sing N N 20  
A1IOL C6    C19    sing N N 21  
A1IOL C6    C7     sing N N 22  
A1IOL C19   N4     sing N N 23  
A1IOL C13   C14    sing N N 24  
A1IOL N4    C10    sing N N 25  
A1IOL C14   C15    sing N N 26  
A1IOL O2    C7     sing N N 27  
A1IOL C7    C20    sing N N 28  
A1IOL C7    C8     sing N N 29  
A1IOL C18   C17    sing N N 30  
A1IOL N6    C17    sing N N 31  
A1IOL N6    C16    sing N N 32  
A1IOL C15   C16    sing N N 33  
A1IOL C10   C9     sing N N 34  
A1IOL C17   O5     doub N N 35  
A1IOL C8    C9     sing N N 36  
A1IOL C9    O3     sing N N 37  
A1IOL C5    H4     sing N N 38  
A1IOL C5    H6     sing N N 39  
A1IOL C5    H5     sing N N 40  
A1IOL C6    H      sing N N 41  
A1IOL C8    H9     sing N N 42  
A1IOL C8    H8     sing N N 43  
A1IOL C10   H12    sing N N 44  
A1IOL C10   H11    sing N N 45  
A1IOL C13   H15    sing N N 46  
A1IOL C13   H16    sing N N 47  
A1IOL C15   H19    sing N N 48  
A1IOL C15   H20    sing N N 49  
A1IOL C20   H29    sing N N 50  
A1IOL C20   H31    sing N N 51  
A1IOL C20   H30    sing N N 52  
A1IOL C21   H32    sing N N 53  
A1IOL C21   H33    sing N N 54  
A1IOL C21   H34    sing N N 55  
A1IOL C12   H2     sing N N 56  
A1IOL C14   H18    sing N N 57  
A1IOL C14   H17    sing N N 58  
A1IOL C16   H22    sing N N 59  
A1IOL C16   H21    sing N N 60  
A1IOL C18   H26    sing N N 61  
A1IOL C18   H24    sing N N 62  
A1IOL C18   H25    sing N N 63  
A1IOL C19   H27    sing N N 64  
A1IOL C19   H28    sing N N 65  
A1IOL C3    H3     sing N N 66  
A1IOL C9    H1     sing N N 67  
A1IOL N5    H13    sing N N 68  
A1IOL N5    H35    sing N N 69  
A1IOL N6    H23    sing N N 70  
A1IOL O2    H7     sing N N 71  
A1IOL O3    H10    sing N N 72  
ALA   N     CA     sing N N 73  
ALA   N     H      sing N N 74  
ALA   N     H2     sing N N 75  
ALA   CA    C      sing N N 76  
ALA   CA    CB     sing N N 77  
ALA   CA    HA     sing N N 78  
ALA   C     O      doub N N 79  
ALA   C     OXT    sing N N 80  
ALA   CB    HB1    sing N N 81  
ALA   CB    HB2    sing N N 82  
ALA   CB    HB3    sing N N 83  
ALA   OXT   HXT    sing N N 84  
ARG   N     CA     sing N N 85  
ARG   N     H      sing N N 86  
ARG   N     H2     sing N N 87  
ARG   CA    C      sing N N 88  
ARG   CA    CB     sing N N 89  
ARG   CA    HA     sing N N 90  
ARG   C     O      doub N N 91  
ARG   C     OXT    sing N N 92  
ARG   CB    CG     sing N N 93  
ARG   CB    HB2    sing N N 94  
ARG   CB    HB3    sing N N 95  
ARG   CG    CD     sing N N 96  
ARG   CG    HG2    sing N N 97  
ARG   CG    HG3    sing N N 98  
ARG   CD    NE     sing N N 99  
ARG   CD    HD2    sing N N 100 
ARG   CD    HD3    sing N N 101 
ARG   NE    CZ     sing N N 102 
ARG   NE    HE     sing N N 103 
ARG   CZ    NH1    sing N N 104 
ARG   CZ    NH2    doub N N 105 
ARG   NH1   HH11   sing N N 106 
ARG   NH1   HH12   sing N N 107 
ARG   NH2   HH21   sing N N 108 
ARG   NH2   HH22   sing N N 109 
ARG   OXT   HXT    sing N N 110 
ASN   N     CA     sing N N 111 
ASN   N     H      sing N N 112 
ASN   N     H2     sing N N 113 
ASN   CA    C      sing N N 114 
ASN   CA    CB     sing N N 115 
ASN   CA    HA     sing N N 116 
ASN   C     O      doub N N 117 
ASN   C     OXT    sing N N 118 
ASN   CB    CG     sing N N 119 
ASN   CB    HB2    sing N N 120 
ASN   CB    HB3    sing N N 121 
ASN   CG    OD1    doub N N 122 
ASN   CG    ND2    sing N N 123 
ASN   ND2   HD21   sing N N 124 
ASN   ND2   HD22   sing N N 125 
ASN   OXT   HXT    sing N N 126 
ASP   N     CA     sing N N 127 
ASP   N     H      sing N N 128 
ASP   N     H2     sing N N 129 
ASP   CA    C      sing N N 130 
ASP   CA    CB     sing N N 131 
ASP   CA    HA     sing N N 132 
ASP   C     O      doub N N 133 
ASP   C     OXT    sing N N 134 
ASP   CB    CG     sing N N 135 
ASP   CB    HB2    sing N N 136 
ASP   CB    HB3    sing N N 137 
ASP   CG    OD1    doub N N 138 
ASP   CG    OD2    sing N N 139 
ASP   OD2   HD2    sing N N 140 
ASP   OXT   HXT    sing N N 141 
CYS   N     CA     sing N N 142 
CYS   N     H      sing N N 143 
CYS   N     H2     sing N N 144 
CYS   CA    C      sing N N 145 
CYS   CA    CB     sing N N 146 
CYS   CA    HA     sing N N 147 
CYS   C     O      doub N N 148 
CYS   C     OXT    sing N N 149 
CYS   CB    SG     sing N N 150 
CYS   CB    HB2    sing N N 151 
CYS   CB    HB3    sing N N 152 
CYS   SG    HG     sing N N 153 
CYS   OXT   HXT    sing N N 154 
EDO   C1    O1     sing N N 155 
EDO   C1    C2     sing N N 156 
EDO   C1    H11    sing N N 157 
EDO   C1    H12    sing N N 158 
EDO   O1    HO1    sing N N 159 
EDO   C2    O2     sing N N 160 
EDO   C2    H21    sing N N 161 
EDO   C2    H22    sing N N 162 
EDO   O2    HO2    sing N N 163 
GLN   N     CA     sing N N 164 
GLN   N     H      sing N N 165 
GLN   N     H2     sing N N 166 
GLN   CA    C      sing N N 167 
GLN   CA    CB     sing N N 168 
GLN   CA    HA     sing N N 169 
GLN   C     O      doub N N 170 
GLN   C     OXT    sing N N 171 
GLN   CB    CG     sing N N 172 
GLN   CB    HB2    sing N N 173 
GLN   CB    HB3    sing N N 174 
GLN   CG    CD     sing N N 175 
GLN   CG    HG2    sing N N 176 
GLN   CG    HG3    sing N N 177 
GLN   CD    OE1    doub N N 178 
GLN   CD    NE2    sing N N 179 
GLN   NE2   HE21   sing N N 180 
GLN   NE2   HE22   sing N N 181 
GLN   OXT   HXT    sing N N 182 
GLU   N     CA     sing N N 183 
GLU   N     H      sing N N 184 
GLU   N     H2     sing N N 185 
GLU   CA    C      sing N N 186 
GLU   CA    CB     sing N N 187 
GLU   CA    HA     sing N N 188 
GLU   C     O      doub N N 189 
GLU   C     OXT    sing N N 190 
GLU   CB    CG     sing N N 191 
GLU   CB    HB2    sing N N 192 
GLU   CB    HB3    sing N N 193 
GLU   CG    CD     sing N N 194 
GLU   CG    HG2    sing N N 195 
GLU   CG    HG3    sing N N 196 
GLU   CD    OE1    doub N N 197 
GLU   CD    OE2    sing N N 198 
GLU   OE2   HE2    sing N N 199 
GLU   OXT   HXT    sing N N 200 
GLY   N     CA     sing N N 201 
GLY   N     H      sing N N 202 
GLY   N     H2     sing N N 203 
GLY   CA    C      sing N N 204 
GLY   CA    HA2    sing N N 205 
GLY   CA    HA3    sing N N 206 
GLY   C     O      doub N N 207 
GLY   C     OXT    sing N N 208 
GLY   OXT   HXT    sing N N 209 
HIS   N     CA     sing N N 210 
HIS   N     H      sing N N 211 
HIS   N     H2     sing N N 212 
HIS   CA    C      sing N N 213 
HIS   CA    CB     sing N N 214 
HIS   CA    HA     sing N N 215 
HIS   C     O      doub N N 216 
HIS   C     OXT    sing N N 217 
HIS   CB    CG     sing N N 218 
HIS   CB    HB2    sing N N 219 
HIS   CB    HB3    sing N N 220 
HIS   CG    ND1    sing Y N 221 
HIS   CG    CD2    doub Y N 222 
HIS   ND1   CE1    doub Y N 223 
HIS   ND1   HD1    sing N N 224 
HIS   CD2   NE2    sing Y N 225 
HIS   CD2   HD2    sing N N 226 
HIS   CE1   NE2    sing Y N 227 
HIS   CE1   HE1    sing N N 228 
HIS   NE2   HE2    sing N N 229 
HIS   OXT   HXT    sing N N 230 
HOH   O     H1     sing N N 231 
HOH   O     H2     sing N N 232 
ILE   N     CA     sing N N 233 
ILE   N     H      sing N N 234 
ILE   N     H2     sing N N 235 
ILE   CA    C      sing N N 236 
ILE   CA    CB     sing N N 237 
ILE   CA    HA     sing N N 238 
ILE   C     O      doub N N 239 
ILE   C     OXT    sing N N 240 
ILE   CB    CG1    sing N N 241 
ILE   CB    CG2    sing N N 242 
ILE   CB    HB     sing N N 243 
ILE   CG1   CD1    sing N N 244 
ILE   CG1   HG12   sing N N 245 
ILE   CG1   HG13   sing N N 246 
ILE   CG2   HG21   sing N N 247 
ILE   CG2   HG22   sing N N 248 
ILE   CG2   HG23   sing N N 249 
ILE   CD1   HD11   sing N N 250 
ILE   CD1   HD12   sing N N 251 
ILE   CD1   HD13   sing N N 252 
ILE   OXT   HXT    sing N N 253 
LEU   N     CA     sing N N 254 
LEU   N     H      sing N N 255 
LEU   N     H2     sing N N 256 
LEU   CA    C      sing N N 257 
LEU   CA    CB     sing N N 258 
LEU   CA    HA     sing N N 259 
LEU   C     O      doub N N 260 
LEU   C     OXT    sing N N 261 
LEU   CB    CG     sing N N 262 
LEU   CB    HB2    sing N N 263 
LEU   CB    HB3    sing N N 264 
LEU   CG    CD1    sing N N 265 
LEU   CG    CD2    sing N N 266 
LEU   CG    HG     sing N N 267 
LEU   CD1   HD11   sing N N 268 
LEU   CD1   HD12   sing N N 269 
LEU   CD1   HD13   sing N N 270 
LEU   CD2   HD21   sing N N 271 
LEU   CD2   HD22   sing N N 272 
LEU   CD2   HD23   sing N N 273 
LEU   OXT   HXT    sing N N 274 
LYS   N     CA     sing N N 275 
LYS   N     H      sing N N 276 
LYS   N     H2     sing N N 277 
LYS   CA    C      sing N N 278 
LYS   CA    CB     sing N N 279 
LYS   CA    HA     sing N N 280 
LYS   C     O      doub N N 281 
LYS   C     OXT    sing N N 282 
LYS   CB    CG     sing N N 283 
LYS   CB    HB2    sing N N 284 
LYS   CB    HB3    sing N N 285 
LYS   CG    CD     sing N N 286 
LYS   CG    HG2    sing N N 287 
LYS   CG    HG3    sing N N 288 
LYS   CD    CE     sing N N 289 
LYS   CD    HD2    sing N N 290 
LYS   CD    HD3    sing N N 291 
LYS   CE    NZ     sing N N 292 
LYS   CE    HE2    sing N N 293 
LYS   CE    HE3    sing N N 294 
LYS   NZ    HZ1    sing N N 295 
LYS   NZ    HZ2    sing N N 296 
LYS   NZ    HZ3    sing N N 297 
LYS   OXT   HXT    sing N N 298 
MES   O1    C2     sing N N 299 
MES   O1    C6     sing N N 300 
MES   C2    C3     sing N N 301 
MES   C2    H21    sing N N 302 
MES   C2    H22    sing N N 303 
MES   C3    N4     sing N N 304 
MES   C3    H31    sing N N 305 
MES   C3    H32    sing N N 306 
MES   N4    C5     sing N N 307 
MES   N4    C7     sing N N 308 
MES   N4    HN4    sing N N 309 
MES   C5    C6     sing N N 310 
MES   C5    H51    sing N N 311 
MES   C5    H52    sing N N 312 
MES   C6    H61    sing N N 313 
MES   C6    H62    sing N N 314 
MES   C7    C8     sing N N 315 
MES   C7    H71    sing N N 316 
MES   C7    H72    sing N N 317 
MES   C8    S      sing N N 318 
MES   C8    H81    sing N N 319 
MES   C8    H82    sing N N 320 
MES   S     O1S    doub N N 321 
MES   S     O2S    doub N N 322 
MES   S     O3S    sing N N 323 
MET   N     CA     sing N N 324 
MET   N     H      sing N N 325 
MET   N     H2     sing N N 326 
MET   CA    C      sing N N 327 
MET   CA    CB     sing N N 328 
MET   CA    HA     sing N N 329 
MET   C     O      doub N N 330 
MET   C     OXT    sing N N 331 
MET   CB    CG     sing N N 332 
MET   CB    HB2    sing N N 333 
MET   CB    HB3    sing N N 334 
MET   CG    SD     sing N N 335 
MET   CG    HG2    sing N N 336 
MET   CG    HG3    sing N N 337 
MET   SD    CE     sing N N 338 
MET   CE    HE1    sing N N 339 
MET   CE    HE2    sing N N 340 
MET   CE    HE3    sing N N 341 
MET   OXT   HXT    sing N N 342 
PHE   N     CA     sing N N 343 
PHE   N     H      sing N N 344 
PHE   N     H2     sing N N 345 
PHE   CA    C      sing N N 346 
PHE   CA    CB     sing N N 347 
PHE   CA    HA     sing N N 348 
PHE   C     O      doub N N 349 
PHE   C     OXT    sing N N 350 
PHE   CB    CG     sing N N 351 
PHE   CB    HB2    sing N N 352 
PHE   CB    HB3    sing N N 353 
PHE   CG    CD1    doub Y N 354 
PHE   CG    CD2    sing Y N 355 
PHE   CD1   CE1    sing Y N 356 
PHE   CD1   HD1    sing N N 357 
PHE   CD2   CE2    doub Y N 358 
PHE   CD2   HD2    sing N N 359 
PHE   CE1   CZ     doub Y N 360 
PHE   CE1   HE1    sing N N 361 
PHE   CE2   CZ     sing Y N 362 
PHE   CE2   HE2    sing N N 363 
PHE   CZ    HZ     sing N N 364 
PHE   OXT   HXT    sing N N 365 
PRO   N     CA     sing N N 366 
PRO   N     CD     sing N N 367 
PRO   N     H      sing N N 368 
PRO   CA    C      sing N N 369 
PRO   CA    CB     sing N N 370 
PRO   CA    HA     sing N N 371 
PRO   C     O      doub N N 372 
PRO   C     OXT    sing N N 373 
PRO   CB    CG     sing N N 374 
PRO   CB    HB2    sing N N 375 
PRO   CB    HB3    sing N N 376 
PRO   CG    CD     sing N N 377 
PRO   CG    HG2    sing N N 378 
PRO   CG    HG3    sing N N 379 
PRO   CD    HD2    sing N N 380 
PRO   CD    HD3    sing N N 381 
PRO   OXT   HXT    sing N N 382 
SAM   N     CA     sing N N 383 
SAM   N     HN1    sing N N 384 
SAM   N     HN2    sing N N 385 
SAM   CA    C      sing N N 386 
SAM   CA    CB     sing N N 387 
SAM   CA    HA     sing N N 388 
SAM   C     O      doub N N 389 
SAM   C     OXT    sing N N 390 
SAM   CB    CG     sing N N 391 
SAM   CB    HB1    sing N N 392 
SAM   CB    HB2    sing N N 393 
SAM   CG    SD     sing N N 394 
SAM   CG    HG1    sing N N 395 
SAM   CG    HG2    sing N N 396 
SAM   SD    CE     sing N N 397 
SAM   SD    "C5'"  sing N N 398 
SAM   CE    HE1    sing N N 399 
SAM   CE    HE2    sing N N 400 
SAM   CE    HE3    sing N N 401 
SAM   "C5'" "C4'"  sing N N 402 
SAM   "C5'" "H5'1" sing N N 403 
SAM   "C5'" "H5'2" sing N N 404 
SAM   "C4'" "O4'"  sing N N 405 
SAM   "C4'" "C3'"  sing N N 406 
SAM   "C4'" "H4'"  sing N N 407 
SAM   "O4'" "C1'"  sing N N 408 
SAM   "C3'" "O3'"  sing N N 409 
SAM   "C3'" "C2'"  sing N N 410 
SAM   "C3'" "H3'"  sing N N 411 
SAM   "O3'" "HO3'" sing N N 412 
SAM   "C2'" "O2'"  sing N N 413 
SAM   "C2'" "C1'"  sing N N 414 
SAM   "C2'" "H2'"  sing N N 415 
SAM   "O2'" "HO2'" sing N N 416 
SAM   "C1'" N9     sing N N 417 
SAM   "C1'" "H1'"  sing N N 418 
SAM   N9    C8     sing Y N 419 
SAM   N9    C4     sing Y N 420 
SAM   C8    N7     doub Y N 421 
SAM   C8    H8     sing N N 422 
SAM   N7    C5     sing Y N 423 
SAM   C5    C6     sing Y N 424 
SAM   C5    C4     doub Y N 425 
SAM   C6    N6     sing N N 426 
SAM   C6    N1     doub Y N 427 
SAM   N6    HN61   sing N N 428 
SAM   N6    HN62   sing N N 429 
SAM   N1    C2     sing Y N 430 
SAM   C2    N3     doub Y N 431 
SAM   C2    H2     sing N N 432 
SAM   N3    C4     sing Y N 433 
SER   N     CA     sing N N 434 
SER   N     H      sing N N 435 
SER   N     H2     sing N N 436 
SER   CA    C      sing N N 437 
SER   CA    CB     sing N N 438 
SER   CA    HA     sing N N 439 
SER   C     O      doub N N 440 
SER   C     OXT    sing N N 441 
SER   CB    OG     sing N N 442 
SER   CB    HB2    sing N N 443 
SER   CB    HB3    sing N N 444 
SER   OG    HG     sing N N 445 
SER   OXT   HXT    sing N N 446 
THR   N     CA     sing N N 447 
THR   N     H      sing N N 448 
THR   N     H2     sing N N 449 
THR   CA    C      sing N N 450 
THR   CA    CB     sing N N 451 
THR   CA    HA     sing N N 452 
THR   C     O      doub N N 453 
THR   C     OXT    sing N N 454 
THR   CB    OG1    sing N N 455 
THR   CB    CG2    sing N N 456 
THR   CB    HB     sing N N 457 
THR   OG1   HG1    sing N N 458 
THR   CG2   HG21   sing N N 459 
THR   CG2   HG22   sing N N 460 
THR   CG2   HG23   sing N N 461 
THR   OXT   HXT    sing N N 462 
TRP   N     CA     sing N N 463 
TRP   N     H      sing N N 464 
TRP   N     H2     sing N N 465 
TRP   CA    C      sing N N 466 
TRP   CA    CB     sing N N 467 
TRP   CA    HA     sing N N 468 
TRP   C     O      doub N N 469 
TRP   C     OXT    sing N N 470 
TRP   CB    CG     sing N N 471 
TRP   CB    HB2    sing N N 472 
TRP   CB    HB3    sing N N 473 
TRP   CG    CD1    doub Y N 474 
TRP   CG    CD2    sing Y N 475 
TRP   CD1   NE1    sing Y N 476 
TRP   CD1   HD1    sing N N 477 
TRP   CD2   CE2    doub Y N 478 
TRP   CD2   CE3    sing Y N 479 
TRP   NE1   CE2    sing Y N 480 
TRP   NE1   HE1    sing N N 481 
TRP   CE2   CZ2    sing Y N 482 
TRP   CE3   CZ3    doub Y N 483 
TRP   CE3   HE3    sing N N 484 
TRP   CZ2   CH2    doub Y N 485 
TRP   CZ2   HZ2    sing N N 486 
TRP   CZ3   CH2    sing Y N 487 
TRP   CZ3   HZ3    sing N N 488 
TRP   CH2   HH2    sing N N 489 
TRP   OXT   HXT    sing N N 490 
TYR   N     CA     sing N N 491 
TYR   N     H      sing N N 492 
TYR   N     H2     sing N N 493 
TYR   CA    C      sing N N 494 
TYR   CA    CB     sing N N 495 
TYR   CA    HA     sing N N 496 
TYR   C     O      doub N N 497 
TYR   C     OXT    sing N N 498 
TYR   CB    CG     sing N N 499 
TYR   CB    HB2    sing N N 500 
TYR   CB    HB3    sing N N 501 
TYR   CG    CD1    doub Y N 502 
TYR   CG    CD2    sing Y N 503 
TYR   CD1   CE1    sing Y N 504 
TYR   CD1   HD1    sing N N 505 
TYR   CD2   CE2    doub Y N 506 
TYR   CD2   HD2    sing N N 507 
TYR   CE1   CZ     doub Y N 508 
TYR   CE1   HE1    sing N N 509 
TYR   CE2   CZ     sing Y N 510 
TYR   CE2   HE2    sing N N 511 
TYR   CZ    OH     sing N N 512 
TYR   OH    HH     sing N N 513 
TYR   OXT   HXT    sing N N 514 
VAL   N     CA     sing N N 515 
VAL   N     H      sing N N 516 
VAL   N     H2     sing N N 517 
VAL   CA    C      sing N N 518 
VAL   CA    CB     sing N N 519 
VAL   CA    HA     sing N N 520 
VAL   C     O      doub N N 521 
VAL   C     OXT    sing N N 522 
VAL   CB    CG1    sing N N 523 
VAL   CB    CG2    sing N N 524 
VAL   CB    HB     sing N N 525 
VAL   CG1   HG11   sing N N 526 
VAL   CG1   HG12   sing N N 527 
VAL   CG1   HG13   sing N N 528 
VAL   CG2   HG21   sing N N 529 
VAL   CG2   HG22   sing N N 530 
VAL   CG2   HG23   sing N N 531 
VAL   OXT   HXT    sing N N 532 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           'DESY Strategy Fund MUXCOSDYN' 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7JIB 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9GUY 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.005966 
_atom_sites.fract_transf_matrix[1][2]   0.003445 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006889 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.019365 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CL 
H  
N  
O  
S  
ZN 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N      . SER   A  1 1   ? 82.585  -47.123 3.510   1.00 96.48  ?  6799 SER   B N      1 
ATOM   2    C  CA     . SER   A  1 1   ? 83.141  -48.045 2.530   1.00 89.72  ?  6799 SER   B CA     1 
ATOM   3    C  C      . SER   A  1 1   ? 83.626  -47.273 1.304   1.00 82.84  ?  6799 SER   B C      1 
ATOM   4    O  O      . SER   A  1 1   ? 84.522  -46.437 1.406   1.00 64.23  ?  6799 SER   B O      1 
ATOM   5    C  CB     . SER   A  1 1   ? 82.097  -49.085 2.124   1.00 92.15  ?  6799 SER   B CB     1 
ATOM   6    O  OG     . SER   A  1 1   ? 81.058  -48.509 1.355   1.00 93.88  ?  6799 SER   B OG     1 
ATOM   7    H  HA     . SER   A  1 1   ? 83.894  -48.520 2.915   1.00 108.18 ?  6799 SER   B HA     1 
ATOM   8    H  HB2    . SER   A  1 1   ? 82.531  -49.774 1.596   1.00 111.11 ?  6799 SER   B HB2    1 
ATOM   9    H  HB3    . SER   A  1 1   ? 81.715  -49.473 2.926   1.00 111.11 ?  6799 SER   B HB3    1 
ATOM   10   H  HG     . SER   A  1 1   ? 80.503  -49.100 1.134   1.00 113.18 ?  6799 SER   B HG     1 
ATOM   11   N  N      . SER   A  1 2   ? 83.011  -47.538 0.149   1.00 78.71  ?  6800 SER   B N      1 
ATOM   12   C  CA     . SER   A  1 2   ? 83.378  -46.872 -1.095  1.00 85.09  ?  6800 SER   B CA     1 
ATOM   13   C  C      . SER   A  1 2   ? 83.244  -45.356 -1.022  1.00 75.89  ?  6800 SER   B C      1 
ATOM   14   O  O      . SER   A  1 2   ? 83.634  -44.672 -1.982  1.00 55.27  ?  6800 SER   B O      1 
ATOM   15   C  CB     . SER   A  1 2   ? 82.489  -47.376 -2.230  1.00 79.81  ?  6800 SER   B CB     1 
ATOM   16   O  OG     . SER   A  1 2   ? 82.949  -48.596 -2.774  1.00 82.21  ?  6800 SER   B OG     1 
ATOM   17   H  H      . SER   A  1 2   ? 82.371  -48.106 0.061   1.00 94.97  ?  6800 SER   B H      1 
ATOM   18   H  HA     . SER   A  1 2   ? 84.303  -47.090 -1.290  1.00 102.63 ?  6800 SER   B HA     1 
ATOM   19   H  HB2    . SER   A  1 2   ? 81.592  -47.510 -1.884  1.00 96.29  ?  6800 SER   B HB2    1 
ATOM   20   H  HB3    . SER   A  1 2   ? 82.477  -46.709 -2.933  1.00 96.29  ?  6800 SER   B HB3    1 
ATOM   21   H  HG     . SER   A  1 2   ? 82.429  -48.854 -3.381  1.00 99.17  ?  6800 SER   B HG     1 
ATOM   22   N  N      . GLN   A  1 3   ? 82.711  -44.812 0.079   1.00 62.09  ?  6801 GLN   B N      1 
ATOM   23   C  CA     . GLN   A  1 3   ? 82.531  -43.369 0.177   1.00 54.55  ?  6801 GLN   B CA     1 
ATOM   24   C  C      . GLN   A  1 3   ? 83.862  -42.643 -0.018  1.00 48.81  ?  6801 GLN   B C      1 
ATOM   25   O  O      . GLN   A  1 3   ? 83.884  -41.486 -0.457  1.00 51.25  ?  6801 GLN   B O      1 
ATOM   26   C  CB     . GLN   A  1 3   ? 81.915  -43.022 1.538   1.00 52.60  ?  6801 GLN   B CB     1 
ATOM   27   C  CG     . GLN   A  1 3   ? 80.394  -42.820 1.486   1.00 59.73  ?  6801 GLN   B CG     1 
ATOM   28   C  CD     . GLN   A  1 3   ? 79.698  -42.836 2.808   1.00 87.61  ?  6801 GLN   B CD     1 
ATOM   29   O  OE1    . GLN   A  1 3   ? 78.476  -42.833 2.865   1.00 73.26  ?  6801 GLN   B OE1    1 
ATOM   30   N  NE2    . GLN   A  1 3   ? 80.452  -42.743 3.871   1.00 69.11  ?  6801 GLN   B NE2    1 
ATOM   31   H  H      . GLN   A  1 3   ? 82.451  -45.254 0.769   1.00 75.03  ?  6801 GLN   B H      1 
ATOM   32   H  HA     . GLN   A  1 3   ? 81.919  -43.064 -0.511  1.00 65.98  ?  6801 GLN   B HA     1 
ATOM   33   H  HB2    . GLN   A  1 3   ? 82.098  -43.745 2.158   1.00 63.64  ?  6801 GLN   B HB2    1 
ATOM   34   H  HB3    . GLN   A  1 3   ? 82.313  -42.199 1.861   1.00 63.64  ?  6801 GLN   B HB3    1 
ATOM   35   H  HG2    . GLN   A  1 3   ? 80.213  -41.960 1.075   1.00 72.20  ?  6801 GLN   B HG2    1 
ATOM   36   H  HG3    . GLN   A  1 3   ? 80.009  -43.531 0.949   1.00 72.20  ?  6801 GLN   B HG3    1 
ATOM   37   H  HE21   . GLN   A  1 3   ? 81.306  -42.677 3.789   1.00 83.46  ?  6801 GLN   B HE21   1 
ATOM   38   H  HE22   . GLN   A  1 3   ? 80.095  -42.748 4.654   1.00 83.46  ?  6801 GLN   B HE22   1 
ATOM   39   N  N      . ALA   A  1 4   ? 84.978  -43.308 0.289   1.00 50.68  ?  6802 ALA   B N      1 
ATOM   40   C  CA     . ALA   A  1 4   ? 86.285  -42.682 0.156   1.00 46.80  ?  6802 ALA   B CA     1 
ATOM   41   C  C      . ALA   A  1 4   ? 86.632  -42.344 -1.291  1.00 44.62  ?  6802 ALA   B C      1 
ATOM   42   O  O      . ALA   A  1 4   ? 87.454  -41.451 -1.514  1.00 42.05  ?  6802 ALA   B O      1 
ATOM   43   C  CB     . ALA   A  1 4   ? 87.363  -43.589 0.756   1.00 46.27  ?  6802 ALA   B CB     1 
ATOM   44   H  H      . ALA   A  1 4   ? 85.001  -44.119 0.574   1.00 61.34  ?  6802 ALA   B H      1 
ATOM   45   H  HA     . ALA   A  1 4   ? 86.278  -41.850 0.655   1.00 56.68  ?  6802 ALA   B HA     1 
ATOM   46   H  HB1    . ALA   A  1 4   ? 88.228  -43.162 0.654   1.00 56.05  ?  6802 ALA   B HB1    1 
ATOM   47   H  HB2    . ALA   A  1 4   ? 87.171  -43.727 1.697   1.00 56.05  ?  6802 ALA   B HB2    1 
ATOM   48   H  HB3    . ALA   A  1 4   ? 87.356  -44.439 0.290   1.00 56.05  ?  6802 ALA   B HB3    1 
ATOM   49   N  N      . TRP   A  1 5   ? 86.030  -43.006 -2.281  1.00 48.37  ?  6803 TRP   B N      1 
ATOM   50   C  CA     . TRP   A  1 5   ? 86.327  -42.686 -3.675  1.00 42.28  ?  6803 TRP   B CA     1 
ATOM   51   C  C      . TRP   A  1 5   ? 85.317  -41.737 -4.285  1.00 41.69  ?  6803 TRP   B C      1 
ATOM   52   O  O      . TRP   A  1 5   ? 85.448  -41.383 -5.459  1.00 47.21  ?  6803 TRP   B O      1 
ATOM   53   C  CB     . TRP   A  1 5   ? 86.411  -43.950 -4.534  1.00 48.39  ?  6803 TRP   B CB     1 
ATOM   54   C  CG     . TRP   A  1 5   ? 87.616  -44.717 -4.202  1.00 49.65  ?  6803 TRP   B CG     1 
ATOM   55   C  CD1    . TRP   A  1 5   ? 88.849  -44.610 -4.773  1.00 49.94  ?  6803 TRP   B CD1    1 
ATOM   56   C  CD2    . TRP   A  1 5   ? 87.729  -45.681 -3.164  1.00 44.09  ?  6803 TRP   B CD2    1 
ATOM   57   N  NE1    . TRP   A  1 5   ? 89.729  -45.464 -4.147  1.00 47.51  ?  6803 TRP   B NE1    1 
ATOM   58   C  CE2    . TRP   A  1 5   ? 89.056  -46.143 -3.161  1.00 45.39  ?  6803 TRP   B CE2    1 
ATOM   59   C  CE3    . TRP   A  1 5   ? 86.827  -46.212 -2.244  1.00 50.16  ?  6803 TRP   B CE3    1 
ATOM   60   C  CZ2    . TRP   A  1 5   ? 89.502  -47.120 -2.267  1.00 46.27  ?  6803 TRP   B CZ2    1 
ATOM   61   C  CZ3    . TRP   A  1 5   ? 87.268  -47.182 -1.361  1.00 57.94  ?  6803 TRP   B CZ3    1 
ATOM   62   C  CH2    . TRP   A  1 5   ? 88.592  -47.623 -1.378  1.00 50.35  ?  6803 TRP   B CH2    1 
ATOM   63   H  H      . TRP   A  1 5   ? 85.454  -43.635 -2.170  1.00 58.56  ?  6803 TRP   B H      1 
ATOM   64   H  HA     . TRP   A  1 5   ? 87.201  -42.266 -3.698  1.00 51.26  ?  6803 TRP   B HA     1 
ATOM   65   H  HB2    . TRP   A  1 5   ? 85.634  -44.506 -4.370  1.00 58.59  ?  6803 TRP   B HB2    1 
ATOM   66   H  HB3    . TRP   A  1 5   ? 86.450  -43.703 -5.472  1.00 58.59  ?  6803 TRP   B HB3    1 
ATOM   67   H  HD1    . TRP   A  1 5   ? 89.064  -44.044 -5.479  1.00 60.45  ?  6803 TRP   B HD1    1 
ATOM   68   H  HE1    . TRP   A  1 5   ? 90.561  -45.556 -4.341  1.00 57.54  ?  6803 TRP   B HE1    1 
ATOM   69   H  HE3    . TRP   A  1 5   ? 85.944  -45.920 -2.224  1.00 60.71  ?  6803 TRP   B HE3    1 
ATOM   70   H  HZ2    . TRP   A  1 5   ? 90.383  -47.417 -2.276  1.00 56.05  ?  6803 TRP   B HZ2    1 
ATOM   71   H  HZ3    . TRP   A  1 5   ? 86.673  -47.546 -0.746  1.00 70.05  ?  6803 TRP   B HZ3    1 
ATOM   72   H  HH2    . TRP   A  1 5   ? 88.862  -48.274 -0.771  1.00 60.94  ?  6803 TRP   B HH2    1 
ATOM   73   N  N      . GLN   A  1 6   ? 84.310  -41.339 -3.532  1.00 47.09  ?  6804 GLN   B N      1 
ATOM   74   C  CA     . GLN   A  1 6   ? 83.414  -40.280 -3.949  1.00 46.23  ?  6804 GLN   B CA     1 
ATOM   75   C  C      . GLN   A  1 6   ? 84.024  -38.923 -3.630  1.00 39.89  ?  6804 GLN   B C      1 
ATOM   76   O  O      . GLN   A  1 6   ? 84.957  -38.822 -2.823  1.00 41.32  ?  6804 GLN   B O      1 
ATOM   77   C  CB     . GLN   A  1 6   ? 82.074  -40.447 -3.245  1.00 46.46  ?  6804 GLN   B CB     1 
ATOM   78   C  CG     . GLN   A  1 6   ? 81.367  -41.718 -3.628  1.00 47.58  ?  6804 GLN   B CG     1 
ATOM   79   C  CD     . GLN   A  1 6   ? 81.167  -41.868 -5.124  1.00 60.94  ?  6804 GLN   B CD     1 
ATOM   80   O  OE1    . GLN   A  1 6   ? 80.787  -40.921 -5.808  1.00 61.90  ?  6804 GLN   B OE1    1 
ATOM   81   N  NE2    . GLN   A  1 6   ? 81.492  -43.039 -5.649  1.00 69.89  ?  6804 GLN   B NE2    1 
ATOM   82   H  H      . GLN   A  1 6   ? 84.120  -41.672 -2.762  1.00 57.03  ?  6804 GLN   B H      1 
ATOM   83   H  HA     . GLN   A  1 6   ? 83.259  -40.320 -4.906  1.00 56.00  ?  6804 GLN   B HA     1 
ATOM   84   H  HB2    . GLN   A  1 6   ? 82.221  -40.463 -2.286  1.00 56.28  ?  6804 GLN   B HB2    1 
ATOM   85   H  HB3    . GLN   A  1 6   ? 81.499  -39.702 -3.480  1.00 56.28  ?  6804 GLN   B HB3    1 
ATOM   86   H  HG2    . GLN   A  1 6   ? 81.892  -42.474 -3.321  1.00 57.62  ?  6804 GLN   B HG2    1 
ATOM   87   H  HG3    . GLN   A  1 6   ? 80.492  -41.730 -3.209  1.00 57.62  ?  6804 GLN   B HG3    1 
ATOM   88   H  HE21   . GLN   A  1 6   ? 81.798  -43.666 -5.146  1.00 84.39  ?  6804 GLN   B HE21   1 
ATOM   89   H  HE22   . GLN   A  1 6   ? 81.396  -43.173 -6.494  1.00 84.39  ?  6804 GLN   B HE22   1 
ATOM   90   N  N      . PRO   A  1 7   ? 83.545  -37.865 -4.290  1.00 38.75  ?  6805 PRO   B N      1 
ATOM   91   C  CA     . PRO   A  1 7   ? 83.962  -36.508 -3.899  1.00 40.27  ?  6805 PRO   B CA     1 
ATOM   92   C  C      . PRO   A  1 7   ? 83.525  -36.160 -2.486  1.00 37.63  ?  6805 PRO   B C      1 
ATOM   93   O  O      . PRO   A  1 7   ? 84.131  -35.297 -1.848  1.00 40.16  ?  6805 PRO   B O      1 
ATOM   94   C  CB     . PRO   A  1 7   ? 83.281  -35.606 -4.939  1.00 41.34  ?  6805 PRO   B CB     1 
ATOM   95   C  CG     . PRO   A  1 7   ? 82.094  -36.404 -5.382  1.00 38.42  ?  6805 PRO   B CG     1 
ATOM   96   C  CD     . PRO   A  1 7   ? 82.561  -37.854 -5.384  1.00 40.12  ?  6805 PRO   B CD     1 
ATOM   97   H  HA     . PRO   A  1 7   ? 84.922  -36.403 -3.986  1.00 48.85  ?  6805 PRO   B HA     1 
ATOM   98   H  HB2    . PRO   A  1 7   ? 83.009  -34.769 -4.530  1.00 50.13  ?  6805 PRO   B HB2    1 
ATOM   99   H  HB3    . PRO   A  1 7   ? 83.884  -35.434 -5.679  1.00 50.13  ?  6805 PRO   B HB3    1 
ATOM   100  H  HG2    . PRO   A  1 7   ? 81.361  -36.278 -4.758  1.00 46.62  ?  6805 PRO   B HG2    1 
ATOM   101  H  HG3    . PRO   A  1 7   ? 81.823  -36.127 -6.271  1.00 46.62  ?  6805 PRO   B HG3    1 
ATOM   102  H  HD2    . PRO   A  1 7   ? 81.825  -38.459 -5.199  1.00 48.67  ?  6805 PRO   B HD2    1 
ATOM   103  H  HD3    . PRO   A  1 7   ? 82.976  -38.086 -6.230  1.00 48.67  ?  6805 PRO   B HD3    1 
ATOM   104  N  N      . GLY   A  1 8   ? 82.493  -36.820 -1.982  1.00 43.26  ?  6806 GLY   B N      1 
ATOM   105  C  CA     . GLY   A  1 8   ? 82.030  -36.563 -0.642  1.00 41.22  ?  6806 GLY   B CA     1 
ATOM   106  C  C      . GLY   A  1 8   ? 80.780  -37.354 -0.361  1.00 37.03  ?  6806 GLY   B C      1 
ATOM   107  O  O      . GLY   A  1 8   ? 80.462  -38.314 -1.063  1.00 48.03  ?  6806 GLY   B O      1 
ATOM   108  H  H      . GLY   A  1 8   ? 82.046  -37.423 -2.402  1.00 52.43  ?  6806 GLY   B H      1 
ATOM   109  H  HA2    . GLY   A  1 8   ? 82.714  -36.818 -0.002  1.00 49.98  ?  6806 GLY   B HA2    1 
ATOM   110  H  HA3    . GLY   A  1 8   ? 81.835  -35.618 -0.536  1.00 49.98  ?  6806 GLY   B HA3    1 
ATOM   111  N  N      . VAL   A  1 9   ? 80.062  -36.927 0.672   1.00 39.61  ?  6807 VAL   B N      1 
ATOM   112  C  CA     . VAL   A  1 9   ? 78.872  -37.621 1.147   1.00 41.44  ?  6807 VAL   B CA     1 
ATOM   113  C  C      . VAL   A  1 9   ? 77.719  -36.631 1.261   1.00 36.50  ?  6807 VAL   B C      1 
ATOM   114  O  O      . VAL   A  1 9   ? 77.856  -35.574 1.885   1.00 41.34  ?  6807 VAL   B O      1 
ATOM   115  C  CB     . VAL   A  1 9   ? 79.118  -38.309 2.499   1.00 37.87  ?  6807 VAL   B CB     1 
ATOM   116  C  CG1    . VAL   A  1 9   ? 77.928  -39.162 2.902   1.00 43.59  ?  6807 VAL   B CG1    1 
ATOM   117  C  CG2    . VAL   A  1 9   ? 80.374  -39.164 2.440   1.00 43.97  ?  6807 VAL   B CG2    1 
ATOM   118  H  H      . VAL   A  1 9   ? 80.250  -36.220 1.125   1.00 48.06  ?  6807 VAL   B H      1 
ATOM   119  H  HA     . VAL   A  1 9   ? 78.623  -38.292 0.492   1.00 50.25  ?  6807 VAL   B HA     1 
ATOM   120  H  HB     . VAL   A  1 9   ? 79.240  -37.621 3.172   1.00 45.97  ?  6807 VAL   B HB     1 
ATOM   121  H  HG11   . VAL   A  1 9   ? 78.168  -39.693 3.677   1.00 52.83  ?  6807 VAL   B HG11   1 
ATOM   122  H  HG12   . VAL   A  1 9   ? 77.181  -38.581 3.116   1.00 52.83  ?  6807 VAL   B HG12   1 
ATOM   123  H  HG13   . VAL   A  1 9   ? 77.692  -39.744 2.163   1.00 52.83  ?  6807 VAL   B HG13   1 
ATOM   124  H  HG21   . VAL   A  1 9   ? 80.401  -39.741 3.220   1.00 53.28  ?  6807 VAL   B HG21   1 
ATOM   125  H  HG22   . VAL   A  1 9   ? 80.353  -39.701 1.632   1.00 53.28  ?  6807 VAL   B HG22   1 
ATOM   126  H  HG23   . VAL   A  1 9   ? 81.151  -38.584 2.431   1.00 53.28  ?  6807 VAL   B HG23   1 
ATOM   127  N  N      . ALA   A  1 10  ? 76.575  -36.998 0.701   1.00 39.59  ?  6808 ALA   B N      1 
ATOM   128  C  CA     . ALA   A  1 10  ? 75.353  -36.220 0.821   1.00 38.69  ?  6808 ALA   B CA     1 
ATOM   129  C  C      . ALA   A  1 10  ? 74.460  -36.801 1.913   1.00 36.76  ?  6808 ALA   B C      1 
ATOM   130  O  O      . ALA   A  1 10  ? 74.421  -38.012 2.137   1.00 42.20  ?  6808 ALA   B O      1 
ATOM   131  C  CB     . ALA   A  1 10  ? 74.607  -36.173 -0.509  1.00 38.57  ?  6808 ALA   B CB     1 
ATOM   132  H  H      . ALA   A  1 10  ? 76.479  -37.713 0.234   1.00 48.04  ?  6808 ALA   B H      1 
ATOM   133  H  HA     . ALA   A  1 10  ? 75.572  -35.309 1.071   1.00 46.95  ?  6808 ALA   B HA     1 
ATOM   134  H  HB1    . ALA   A  1 10  ? 73.811  -35.628 -0.405  1.00 46.81  ?  6808 ALA   B HB1    1 
ATOM   135  H  HB2    . ALA   A  1 10  ? 75.187  -35.786 -1.183  1.00 46.81  ?  6808 ALA   B HB2    1 
ATOM   136  H  HB3    . ALA   A  1 10  ? 74.359  -37.076 -0.764  1.00 46.81  ?  6808 ALA   B HB3    1 
ATOM   137  N  N      . MET   A  1 11  ? 73.733  -35.910 2.589   1.00 44.16  ?  6809 MET   B N      1 
ATOM   138  C  CA     . MET   A  1 11  ? 72.799  -36.279 3.643   1.00 38.36  ?  6809 MET   B CA     1 
ATOM   139  C  C      . MET   A  1 11  ? 71.819  -37.344 3.152   1.00 37.17  ?  6809 MET   B C      1 
ATOM   140  O  O      . MET   A  1 11  ? 71.023  -37.067 2.237   1.00 38.01  ?  6809 MET   B O      1 
ATOM   141  C  CB     . MET   A  1 11  ? 71.981  -35.079 4.091   1.00 44.06  ?  6809 MET   B CB     1 
ATOM   142  C  CG     . MET   A  1 11  ? 71.432  -35.187 5.499   1.00 37.07  ?  6809 MET   B CG     1 
ATOM   143  S  SD     . MET   A  1 11  ? 70.888  -33.569 6.080   1.00 43.13  ?  6809 MET   B SD     1 
ATOM   144  C  CE     . MET   A  1 11  ? 69.521  -34.047 7.134   1.00 39.48  ?  6809 MET   B CE     1 
ATOM   145  H  H      . MET   A  1 11  ? 73.767  -35.062 2.449   1.00 53.52  ?  6809 MET   B H      1 
ATOM   146  H  HA     . MET   A  1 11  ? 73.325  -36.607 4.389   1.00 46.55  ?  6809 MET   B HA     1 
ATOM   147  H  HB2    . MET   A  1 11  ? 72.544  -34.290 4.055   1.00 53.39  ?  6809 MET   B HB2    1 
ATOM   148  H  HB3    . MET   A  1 11  ? 71.227  -34.977 3.489   1.00 53.39  ?  6809 MET   B HB3    1 
ATOM   149  H  HG2    . MET   A  1 11  ? 70.673  -35.792 5.508   1.00 45.00  ?  6809 MET   B HG2    1 
ATOM   150  H  HG3    . MET   A  1 11  ? 72.124  -35.515 6.095   1.00 45.00  ?  6809 MET   B HG3    1 
ATOM   151  H  HE1    . MET   A  1 11  ? 69.129  -33.249 7.523   1.00 47.90  ?  6809 MET   B HE1    1 
ATOM   152  H  HE2    . MET   A  1 11  ? 68.860  -34.514 6.600   1.00 47.90  ?  6809 MET   B HE2    1 
ATOM   153  H  HE3    . MET   A  1 11  ? 69.852  -34.629 7.835   1.00 47.90  ?  6809 MET   B HE3    1 
ATOM   154  N  N      . PRO   A  1 12  ? 71.794  -38.531 3.754   1.00 39.98  ?  6810 PRO   B N      1 
ATOM   155  C  CA     . PRO   A  1 12  ? 70.811  -39.539 3.334   1.00 42.53  ?  6810 PRO   B CA     1 
ATOM   156  C  C      . PRO   A  1 12  ? 69.389  -39.083 3.622   1.00 46.94  ?  6810 PRO   B C      1 
ATOM   157  O  O      . PRO   A  1 12  ? 69.107  -38.478 4.661   1.00 40.83  ?  6810 PRO   B O      1 
ATOM   158  C  CB     . PRO   A  1 12  ? 71.181  -40.773 4.159   1.00 44.24  ?  6810 PRO   B CB     1 
ATOM   159  C  CG     . PRO   A  1 12  ? 72.621  -40.565 4.550   1.00 39.55  ?  6810 PRO   B CG     1 
ATOM   160  C  CD     . PRO   A  1 12  ? 72.784  -39.072 4.700   1.00 39.34  ?  6810 PRO   B CD     1 
ATOM   161  H  HA     . PRO   A  1 12  ? 70.906  -39.739 2.390   1.00 51.56  ?  6810 PRO   B HA     1 
ATOM   162  H  HB2    . PRO   A  1 12  ? 70.613  -40.829 4.944   1.00 53.61  ?  6810 PRO   B HB2    1 
ATOM   163  H  HB3    . PRO   A  1 12  ? 71.081  -41.573 3.620   1.00 53.61  ?  6810 PRO   B HB3    1 
ATOM   164  H  HG2    . PRO   A  1 12  ? 72.803  -41.017 5.389   1.00 47.98  ?  6810 PRO   B HG2    1 
ATOM   165  H  HG3    . PRO   A  1 12  ? 73.203  -40.908 3.855   1.00 47.98  ?  6810 PRO   B HG3    1 
ATOM   166  H  HD2    . PRO   A  1 12  ? 72.586  -38.791 5.607   1.00 47.73  ?  6810 PRO   B HD2    1 
ATOM   167  H  HD3    . PRO   A  1 12  ? 73.682  -38.796 4.456   1.00 47.73  ?  6810 PRO   B HD3    1 
ATOM   168  N  N      . ASN   A  1 13  ? 68.480  -39.410 2.698   1.00 47.61  ?  6811 ASN   B N      1 
ATOM   169  C  CA     . ASN   A  1 13  ? 67.131  -38.863 2.780   1.00 39.35  ?  6811 ASN   B CA     1 
ATOM   170  C  C      . ASN   A  1 13  ? 66.480  -39.184 4.120   1.00 44.23  ?  6811 ASN   B C      1 
ATOM   171  O  O      . ASN   A  1 13  ? 65.746  -38.359 4.674   1.00 49.25  ?  6811 ASN   B O      1 
ATOM   172  C  CB     . ASN   A  1 13  ? 66.281  -39.395 1.634   1.00 42.27  ?  6811 ASN   B CB     1 
ATOM   173  C  CG     . ASN   A  1 13  ? 66.653  -38.747 0.320   1.00 40.79  ?  6811 ASN   B CG     1 
ATOM   174  O  OD1    . ASN   A  1 13  ? 67.352  -37.732 0.306   1.00 50.11  ?  6811 ASN   B OD1    1 
ATOM   175  N  ND2    . ASN   A  1 13  ? 66.158  -39.292 -0.784  1.00 47.94  ?  6811 ASN   B ND2    1 
ATOM   176  H  H      . ASN   A  1 13  ? 68.619  -39.934 2.031   1.00 57.66  ?  6811 ASN   B H      1 
ATOM   177  H  HA     . ASN   A  1 13  ? 67.181  -37.898 2.695   1.00 47.74  ?  6811 ASN   B HA     1 
ATOM   178  H  HB2    . ASN   A  1 13  ? 66.417  -40.352 1.551   1.00 51.24  ?  6811 ASN   B HB2    1 
ATOM   179  H  HB3    . ASN   A  1 13  ? 65.347  -39.206 1.813   1.00 51.24  ?  6811 ASN   B HB3    1 
ATOM   180  H  HD21   . ASN   A  1 13  ? 66.346  -38.954 -1.552  1.00 58.05  ?  6811 ASN   B HD21   1 
ATOM   181  H  HD22   . ASN   A  1 13  ? 65.650  -39.984 -0.731  1.00 58.05  ?  6811 ASN   B HD22   1 
ATOM   182  N  N      . LEU   A  1 14  ? 66.736  -40.371 4.669   1.00 45.42  ?  6812 LEU   B N      1 
ATOM   183  C  CA     . LEU   A  1 14  ? 66.063  -40.727 5.912   1.00 44.06  ?  6812 LEU   B CA     1 
ATOM   184  C  C      . LEU   A  1 14  ? 66.418  -39.770 7.041   1.00 44.71  ?  6812 LEU   B C      1 
ATOM   185  O  O      . LEU   A  1 14  ? 65.623  -39.580 7.969   1.00 47.78  ?  6812 LEU   B O      1 
ATOM   186  C  CB     . LEU   A  1 14  ? 66.399  -42.161 6.303   1.00 49.01  ?  6812 LEU   B CB     1 
ATOM   187  C  CG     . LEU   A  1 14  ? 65.579  -42.654 7.493   1.00 44.37  ?  6812 LEU   B CG     1 
ATOM   188  C  CD1    . LEU   A  1 14  ? 64.091  -42.460 7.327   1.00 46.35  ?  6812 LEU   B CD1    1 
ATOM   189  C  CD2    . LEU   A  1 14  ? 65.894  -44.149 7.718   1.00 47.12  ?  6812 LEU   B CD2    1 
ATOM   190  H  H      . LEU   A  1 14  ? 67.273  -40.964 4.353   1.00 55.02  ?  6812 LEU   B H      1 
ATOM   191  H  HA     . LEU   A  1 14  ? 65.105  -40.676 5.769   1.00 53.40  ?  6812 LEU   B HA     1 
ATOM   192  H  HB2    . LEU   A  1 14  ? 66.218  -42.744 5.550   1.00 59.33  ?  6812 LEU   B HB2    1 
ATOM   193  H  HB3    . LEU   A  1 14  ? 67.338  -42.210 6.543   1.00 59.33  ?  6812 LEU   B HB3    1 
ATOM   194  H  HG     . LEU   A  1 14  ? 65.825  -42.125 8.268   1.00 53.77  ?  6812 LEU   B HG     1 
ATOM   195  H  HD11   . LEU   A  1 14  ? 63.629  -42.941 8.031   1.00 56.14  ?  6812 LEU   B HD11   1 
ATOM   196  H  HD12   . LEU   A  1 14  ? 63.887  -41.514 7.384   1.00 56.14  ?  6812 LEU   B HD12   1 
ATOM   197  H  HD13   . LEU   A  1 14  ? 63.823  -42.805 6.460   1.00 56.14  ?  6812 LEU   B HD13   1 
ATOM   198  H  HD21   . LEU   A  1 14  ? 65.404  -44.461 8.495   1.00 57.07  ?  6812 LEU   B HD21   1 
ATOM   199  H  HD22   . LEU   A  1 14  ? 65.623  -44.650 6.933   1.00 57.07  ?  6812 LEU   B HD22   1 
ATOM   200  H  HD23   . LEU   A  1 14  ? 66.847  -44.252 7.864   1.00 57.07  ?  6812 LEU   B HD23   1 
ATOM   201  N  N      . TYR   A  1 15  ? 67.606  -39.164 7.000   1.00 45.84  ?  6813 TYR   B N      1 
ATOM   202  C  CA     . TYR   A  1 15  ? 67.951  -38.213 8.047   1.00 43.92  ?  6813 TYR   B CA     1 
ATOM   203  C  C      . TYR   A  1 15  ? 67.147  -36.924 7.898   1.00 40.40  ?  6813 TYR   B C      1 
ATOM   204  O  O      . TYR   A  1 15  ? 66.840  -36.268 8.903   1.00 40.70  ?  6813 TYR   B O      1 
ATOM   205  C  CB     . TYR   A  1 15  ? 69.458  -37.950 8.034   1.00 43.38  ?  6813 TYR   B CB     1 
ATOM   206  C  CG     . TYR   A  1 15  ? 70.241  -39.083 8.669   1.00 45.68  ?  6813 TYR   B CG     1 
ATOM   207  C  CD1    . TYR   A  1 15  ? 70.301  -39.227 10.046  1.00 42.62  ?  6813 TYR   B CD1    1 
ATOM   208  C  CD2    . TYR   A  1 15  ? 70.911  -40.010 7.881   1.00 40.91  ?  6813 TYR   B CD2    1 
ATOM   209  C  CE1    . TYR   A  1 15  ? 71.002  -40.260 10.622  1.00 42.16  ?  6813 TYR   B CE1    1 
ATOM   210  C  CE2    . TYR   A  1 15  ? 71.620  -41.047 8.449   1.00 44.71  ?  6813 TYR   B CE2    1 
ATOM   211  C  CZ     . TYR   A  1 15  ? 71.659  -41.167 9.826   1.00 39.58  ?  6813 TYR   B CZ     1 
ATOM   212  O  OH     . TYR   A  1 15  ? 72.357  -42.188 10.432  1.00 46.40  ?  6813 TYR   B OH     1 
ATOM   213  H  H      . TYR   A  1 15  ? 68.207  -39.284 6.397   1.00 55.53  ?  6813 TYR   B H      1 
ATOM   214  H  HA     . TYR   A  1 15  ? 67.740  -38.587 8.917   1.00 53.23  ?  6813 TYR   B HA     1 
ATOM   215  H  HB2    . TYR   A  1 15  ? 69.756  -37.854 7.116   1.00 52.58  ?  6813 TYR   B HB2    1 
ATOM   216  H  HB3    . TYR   A  1 15  ? 69.644  -37.138 8.530   1.00 52.58  ?  6813 TYR   B HB3    1 
ATOM   217  H  HD1    . TYR   A  1 15  ? 69.861  -38.614 10.589  1.00 51.67  ?  6813 TYR   B HD1    1 
ATOM   218  H  HD2    . TYR   A  1 15  ? 70.880  -39.931 6.955   1.00 49.62  ?  6813 TYR   B HD2    1 
ATOM   219  H  HE1    . TYR   A  1 15  ? 71.030  -40.345 11.548  1.00 51.12  ?  6813 TYR   B HE1    1 
ATOM   220  H  HE2    . TYR   A  1 15  ? 72.067  -41.660 7.911   1.00 54.17  ?  6813 TYR   B HE2    1 
ATOM   221  H  HH     . TYR   A  1 15  ? 72.704  -42.684 9.850   1.00 56.20  ?  6813 TYR   B HH     1 
ATOM   222  N  N      . LYS   A  1 16  ? 66.764  -36.571 6.660   1.00 43.69  ?  6814 LYS   B N      1 
ATOM   223  C  CA     . LYS   A  1 16  ? 65.964  -35.376 6.412   1.00 42.68  ?  6814 LYS   B CA     1 
ATOM   224  C  C      . LYS   A  1 16  ? 64.557  -35.536 6.978   1.00 39.63  ?  6814 LYS   B C      1 
ATOM   225  O  O      . LYS   A  1 16  ? 63.892  -34.541 7.300   1.00 46.41  ?  6814 LYS   B O      1 
ATOM   226  C  CB     . LYS   A  1 16  ? 65.891  -35.090 4.901   1.00 39.95  ?  6814 LYS   B CB     1 
ATOM   227  C  CG     . LYS   A  1 16  ? 67.208  -35.233 4.142   1.00 42.97  ?  6814 LYS   B CG     1 
ATOM   228  C  CD     . LYS   A  1 16  ? 67.040  -34.941 2.639   1.00 42.64  ?  6814 LYS   B CD     1 
ATOM   229  C  CE     . LYS   A  1 16  ? 68.371  -35.114 1.909   1.00 43.19  ?  6814 LYS   B CE     1 
ATOM   230  N  NZ     . LYS   A  1 16  ? 68.276  -35.036 0.385   1.00 44.97  ?  6814 LYS   B NZ     1 
ATOM   231  H  H      . LYS   A  1 16  ? 66.958  -37.012 5.948   1.00 52.95  ?  6814 LYS   B H      1 
ATOM   232  H  HA     . LYS   A  1 16  ? 66.389  -34.616 6.840   1.00 51.74  ?  6814 LYS   B HA     1 
ATOM   233  H  HB2    . LYS   A  1 16  ? 65.259  -35.710 4.503   1.00 48.46  ?  6814 LYS   B HB2    1 
ATOM   234  H  HB3    . LYS   A  1 16  ? 65.584  -34.178 4.777   1.00 48.46  ?  6814 LYS   B HB3    1 
ATOM   235  H  HG2    . LYS   A  1 16  ? 67.854  -34.606 4.502   1.00 52.09  ?  6814 LYS   B HG2    1 
ATOM   236  H  HG3    . LYS   A  1 16  ? 67.536  -36.141 4.240   1.00 52.09  ?  6814 LYS   B HG3    1 
ATOM   237  H  HD2    . LYS   A  1 16  ? 66.396  -35.558 2.258   1.00 51.69  ?  6814 LYS   B HD2    1 
ATOM   238  H  HD3    . LYS   A  1 16  ? 66.737  -34.028 2.517   1.00 51.69  ?  6814 LYS   B HD3    1 
ATOM   239  H  HE2    . LYS   A  1 16  ? 68.976  -34.414 2.200   1.00 52.35  ?  6814 LYS   B HE2    1 
ATOM   240  H  HE3    . LYS   A  1 16  ? 68.737  -35.984 2.134   1.00 52.35  ?  6814 LYS   B HE3    1 
ATOM   241  H  HZ1    . LYS   A  1 16  ? 69.081  -35.155 0.023   1.00 54.49  ?  6814 LYS   B HZ1    1 
ATOM   242  H  HZ2    . LYS   A  1 16  ? 67.727  -35.667 0.081   1.00 54.49  ?  6814 LYS   B HZ2    1 
ATOM   243  H  HZ3    . LYS   A  1 16  ? 67.964  -34.239 0.140   1.00 54.49  ?  6814 LYS   B HZ3    1 
ATOM   244  N  N      . MET   A  1 17  ? 64.071  -36.765 7.072   1.00 47.98  ?  6815 MET   B N      1 
ATOM   245  C  CA     . MET   A  1 17  ? 62.704  -37.031 7.514   1.00 43.08  ?  6815 MET   B CA     1 
ATOM   246  C  C      . MET   A  1 17  ? 62.556  -37.070 9.027   1.00 38.37  ?  6815 MET   B C      1 
ATOM   247  O  O      . MET   A  1 17  ? 61.445  -37.294 9.516   1.00 54.02  ?  6815 MET   B O      1 
ATOM   248  C  CB     . MET   A  1 17  ? 62.233  -38.351 6.905   1.00 42.73  ?  6815 MET   B CB     1 
ATOM   249  C  CG     . MET   A  1 17  ? 62.425  -38.392 5.417   1.00 41.60  ?  6815 MET   B CG     1 
ATOM   250  S  SD     . MET   A  1 17  ? 61.954  -39.948 4.693   1.00 47.53  ?  6815 MET   B SD     1 
ATOM   251  C  CE     . MET   A  1 17  ? 60.173  -39.909 4.977   1.00 46.07  ?  6815 MET   B CE     1 
ATOM   252  H  H      . MET   A  1 17  ? 64.517  -37.475 6.882   1.00 58.10  ?  6815 MET   B H      1 
ATOM   253  H  HA     . MET   A  1 17  ? 62.126  -36.324 7.187   1.00 52.22  ?  6815 MET   B HA     1 
ATOM   254  H  HB2    . MET   A  1 17  ? 62.741  -39.080 7.295   1.00 51.80  ?  6815 MET   B HB2    1 
ATOM   255  H  HB3    . MET   A  1 17  ? 61.288  -38.468 7.091   1.00 51.80  ?  6815 MET   B HB3    1 
ATOM   256  H  HG2    . MET   A  1 17  ? 61.883  -37.698 5.011   1.00 50.45  ?  6815 MET   B HG2    1 
ATOM   257  H  HG3    . MET   A  1 17  ? 63.362  -38.241 5.217   1.00 50.45  ?  6815 MET   B HG3    1 
ATOM   258  H  HE1    . MET   A  1 17  ? 59.769  -40.681 4.551   1.00 55.80  ?  6815 MET   B HE1    1 
ATOM   259  H  HE2    . MET   A  1 17  ? 60.006  -39.933 5.933   1.00 55.80  ?  6815 MET   B HE2    1 
ATOM   260  H  HE3    . MET   A  1 17  ? 59.811  -39.094 4.598   1.00 55.80  ?  6815 MET   B HE3    1 
ATOM   261  N  N      . GLN   A  1 18  ? 63.631  -36.870 9.777   1.00 41.94  ?  6816 GLN   B N      1 
ATOM   262  C  CA     . GLN   A  1 18  ? 63.543  -37.006 11.216  1.00 44.13  ?  6816 GLN   B CA     1 
ATOM   263  C  C      . GLN   A  1 18  ? 63.010  -35.718 11.831  1.00 43.14  ?  6816 GLN   B C      1 
ATOM   264  O  O      . GLN   A  1 18  ? 62.714  -34.736 11.143  1.00 45.17  ?  6816 GLN   B O      1 
ATOM   265  C  CB     . GLN   A  1 18  ? 64.901  -37.380 11.814  1.00 42.60  ?  6816 GLN   B CB     1 
ATOM   266  C  CG     . GLN   A  1 18  ? 65.443  -38.697 11.251  1.00 44.16  ?  6816 GLN   B CG     1 
ATOM   267  C  CD     . GLN   A  1 18  ? 64.492  -39.862 11.500  1.00 38.51  ?  6816 GLN   B CD     1 
ATOM   268  O  OE1    . GLN   A  1 18  ? 64.118  -40.138 12.636  1.00 45.52  ?  6816 GLN   B OE1    1 
ATOM   269  N  NE2    . GLN   A  1 18  ? 64.085  -40.540 10.432  1.00 43.00  ?  6816 GLN   B NE2    1 
ATOM   270  H  H      . GLN   A  1 18  ? 64.408  -36.658 9.478   1.00 50.85  ?  6816 GLN   B H      1 
ATOM   271  H  HA     . GLN   A  1 18  ? 62.924  -37.726 11.416  1.00 53.48  ?  6816 GLN   B HA     1 
ATOM   272  H  HB2    . GLN   A  1 18  ? 65.541  -36.679 11.612  1.00 51.65  ?  6816 GLN   B HB2    1 
ATOM   273  H  HB3    . GLN   A  1 18  ? 64.809  -37.477 12.775  1.00 51.65  ?  6816 GLN   B HB3    1 
ATOM   274  H  HG2    . GLN   A  1 18  ? 65.567  -38.607 10.293  1.00 53.52  ?  6816 GLN   B HG2    1 
ATOM   275  H  HG3    . GLN   A  1 18  ? 66.290  -38.901 11.677  1.00 53.52  ?  6816 GLN   B HG3    1 
ATOM   276  H  HE21   . GLN   A  1 18  ? 64.358  -40.313 9.649   1.00 52.12  ?  6816 GLN   B HE21   1 
ATOM   277  H  HE22   . GLN   A  1 18  ? 63.548  -41.206 10.524  1.00 52.12  ?  6816 GLN   B HE22   1 
ATOM   278  N  N      A ARG   A  1 19  ? 62.856  -35.753 13.157  0.56 48.12  ?  6817 ARG   B N      1 
ATOM   279  N  N      B ARG   A  1 19  ? 62.874  -35.716 13.155  0.44 48.05  ?  6817 ARG   B N      1 
ATOM   280  C  CA     A ARG   A  1 19  ? 62.453  -34.608 13.956  0.56 43.77  ?  6817 ARG   B CA     1 
ATOM   281  C  CA     B ARG   A  1 19  ? 62.470  -34.533 13.896  0.44 43.84  ?  6817 ARG   B CA     1 
ATOM   282  C  C      A ARG   A  1 19  ? 63.373  -34.513 15.175  0.56 44.23  ?  6817 ARG   B C      1 
ATOM   283  C  C      B ARG   A  1 19  ? 63.354  -34.454 15.146  0.44 44.28  ?  6817 ARG   B C      1 
ATOM   284  O  O      A ARG   A  1 19  ? 62.963  -34.648 16.324  0.56 50.09  ?  6817 ARG   B O      1 
ATOM   285  O  O      B ARG   A  1 19  ? 62.898  -34.543 16.283  0.44 50.12  ?  6817 ARG   B O      1 
ATOM   286  C  CB     A ARG   A  1 19  ? 60.998  -34.702 14.413  0.56 46.52  ?  6817 ARG   B CB     1 
ATOM   287  C  CB     B ARG   A  1 19  ? 60.984  -34.576 14.245  0.44 46.77  ?  6817 ARG   B CB     1 
ATOM   288  C  CG     A ARG   A  1 19  ? 59.981  -34.020 13.512  0.56 52.98  ?  6817 ARG   B CG     1 
ATOM   289  C  CG     B ARG   A  1 19  ? 60.014  -34.758 13.077  0.44 52.62  ?  6817 ARG   B CG     1 
ATOM   290  C  CD     A ARG   A  1 19  ? 58.715  -33.666 14.275  0.56 54.06  ?  6817 ARG   B CD     1 
ATOM   291  C  CD     B ARG   A  1 19  ? 59.608  -33.466 12.365  0.44 49.03  ?  6817 ARG   B CD     1 
ATOM   292  N  NE     A ARG   A  1 19  ? 58.906  -32.488 15.119  0.56 48.51  ?  6817 ARG   B NE     1 
ATOM   293  N  NE     B ARG   A  1 19  ? 60.279  -33.325 11.083  0.44 51.99  ?  6817 ARG   B NE     1 
ATOM   294  C  CZ     A ARG   A  1 19  ? 58.845  -31.236 14.682  0.56 46.09  ?  6817 ARG   B CZ     1 
ATOM   295  C  CZ     B ARG   A  1 19  ? 59.897  -33.927 9.962   0.44 51.24  ?  6817 ARG   B CZ     1 
ATOM   296  N  NH1    A ARG   A  1 19  ? 58.587  -30.958 13.414  0.56 47.81  ?  6817 ARG   B NH1    1 
ATOM   297  N  NH1    B ARG   A  1 19  ? 58.827  -34.705 9.920   0.44 48.30  ?  6817 ARG   B NH1    1 
ATOM   298  N  NH2    A ARG   A  1 19  ? 59.044  -30.237 15.537  0.56 45.94  ?  6817 ARG   B NH2    1 
ATOM   299  N  NH2    B ARG   A  1 19  ? 60.610  -33.744 8.853   0.44 50.35  ?  6817 ARG   B NH2    1 
ATOM   300  H  H      A ARG   A  1 19  ? 62.985  -36.460 13.629  0.56 58.26  ?  6817 ARG   B H      1 
ATOM   301  H  H      B ARG   A  1 19  ? 63.014  -36.404 13.652  0.44 58.19  ?  6817 ARG   B H      1 
ATOM   302  H  HA     A ARG   A  1 19  ? 62.546  -33.816 13.403  0.56 53.04  ?  6817 ARG   B HA     1 
ATOM   303  H  HA     B ARG   A  1 19  ? 62.610  -33.738 13.357  0.44 53.13  ?  6817 ARG   B HA     1 
ATOM   304  H  HB2    A ARG   A  1 19  ? 60.755  -35.640 14.464  0.56 56.35  ?  6817 ARG   B HB2    1 
ATOM   305  H  HB2    B ARG   A  1 19  ? 60.839  -35.318 14.854  0.44 56.64  ?  6817 ARG   B HB2    1 
ATOM   306  H  HB3    A ARG   A  1 19  ? 60.927  -34.292 15.289  0.56 56.35  ?  6817 ARG   B HB3    1 
ATOM   307  H  HB3    B ARG   A  1 19  ? 60.752  -33.741 14.680  0.44 56.64  ?  6817 ARG   B HB3    1 
ATOM   308  H  HG2    A ARG   A  1 19  ? 60.362  -33.202 13.157  0.56 64.09  ?  6817 ARG   B HG2    1 
ATOM   309  H  HG2    B ARG   A  1 19  ? 60.432  -35.334 12.417  0.44 63.66  ?  6817 ARG   B HG2    1 
ATOM   310  H  HG3    A ARG   A  1 19  ? 59.742  -34.618 12.786  0.56 64.09  ?  6817 ARG   B HG3    1 
ATOM   311  H  HG3    B ARG   A  1 19  ? 59.203  -35.172 13.411  0.44 63.66  ?  6817 ARG   B HG3    1 
ATOM   312  H  HD2    A ARG   A  1 19  ? 58.003  -33.476 13.644  0.56 65.40  ?  6817 ARG   B HD2    1 
ATOM   313  H  HD2    B ARG   A  1 19  ? 58.651  -33.473 12.209  0.44 59.36  ?  6817 ARG   B HD2    1 
ATOM   314  H  HD3    A ARG   A  1 19  ? 58.464  -34.410 14.844  0.56 65.40  ?  6817 ARG   B HD3    1 
ATOM   315  H  HD3    B ARG   A  1 19  ? 59.849  -32.706 12.919  0.44 59.36  ?  6817 ARG   B HD3    1 
ATOM   316  H  HE     A ARG   A  1 19  ? 59.067  -32.615 15.954  0.56 58.73  ?  6817 ARG   B HE     1 
ATOM   317  H  HE     B ARG   A  1 19  ? 60.971  -32.817 11.047  0.44 62.91  ?  6817 ARG   B HE     1 
ATOM   318  H  HH11   A ARG   A  1 19  ? 58.453  -31.595 12.852  0.56 57.89  ?  6817 ARG   B HH11   1 
ATOM   319  H  HH11   B ARG   A  1 19  ? 58.359  -34.831 10.631  0.44 58.48  ?  6817 ARG   B HH11   1 
ATOM   320  H  HH12   A ARG   A  1 19  ? 58.552  -30.140 13.152  0.56 57.89  ?  6817 ARG   B HH12   1 
ATOM   321  H  HH12   B ARG   A  1 19  ? 58.599  -35.084 9.183   0.44 58.48  ?  6817 ARG   B HH12   1 
ATOM   322  H  HH21   A ARG   A  1 19  ? 59.209  -30.405 16.364  0.56 55.65  ?  6817 ARG   B HH21   1 
ATOM   323  H  HH21   B ARG   A  1 19  ? 61.308  -33.242 8.868   0.44 60.95  ?  6817 ARG   B HH21   1 
ATOM   324  H  HH22   A ARG   A  1 19  ? 59.007  -29.422 15.263  0.56 55.65  ?  6817 ARG   B HH22   1 
ATOM   325  H  HH22   B ARG   A  1 19  ? 60.373  -34.129 8.121   0.44 60.95  ?  6817 ARG   B HH22   1 
ATOM   326  N  N      . MET   A  1 20  ? 64.661  -34.323 14.926  1.00 48.53  ?  6818 MET   B N      1 
ATOM   327  C  CA     . MET   A  1 20  ? 65.633  -34.305 16.008  1.00 43.67  ?  6818 MET   B CA     1 
ATOM   328  C  C      . MET   A  1 20  ? 65.680  -32.939 16.679  1.00 42.97  ?  6818 MET   B C      1 
ATOM   329  O  O      . MET   A  1 20  ? 65.113  -31.951 16.204  1.00 47.24  ?  6818 MET   B O      1 
ATOM   330  C  CB     . MET   A  1 20  ? 67.032  -34.650 15.489  1.00 45.36  ?  6818 MET   B CB     1 
ATOM   331  C  CG     . MET   A  1 20  ? 67.096  -35.839 14.581  1.00 48.57  ?  6818 MET   B CG     1 
ATOM   332  S  SD     . MET   A  1 20  ? 66.548  -37.295 15.449  1.00 53.61  ?  6818 MET   B SD     1 
ATOM   333  C  CE     . MET   A  1 20  ? 67.629  -37.264 16.872  1.00 49.37  ?  6818 MET   B CE     1 
ATOM   334  H  H      A MET   A  1 20  ? 64.996  -34.204 14.143  0.56 58.76  ?  6818 MET   B H      1 
ATOM   335  H  H      B MET   A  1 20  ? 65.013  -34.243 14.145  0.44 58.76  ?  6818 MET   B H      1 
ATOM   336  H  HA     . MET   A  1 20  ? 65.365  -34.976 16.656  1.00 52.92  ?  6818 MET   B HA     1 
ATOM   337  H  HB2    . MET   A  1 20  ? 67.372  -33.888 14.994  1.00 54.95  ?  6818 MET   B HB2    1 
ATOM   338  H  HB3    . MET   A  1 20  ? 67.605  -34.833 16.250  1.00 54.95  ?  6818 MET   B HB3    1 
ATOM   339  H  HG2    . MET   A  1 20  ? 66.518  -35.697 13.815  1.00 58.81  ?  6818 MET   B HG2    1 
ATOM   340  H  HG3    . MET   A  1 20  ? 68.010  -35.977 14.287  1.00 58.81  ?  6818 MET   B HG3    1 
ATOM   341  H  HE1    . MET   A  1 20  ? 67.700  -38.161 17.235  1.00 59.76  ?  6818 MET   B HE1    1 
ATOM   342  H  HE2    . MET   A  1 20  ? 68.504  -36.948 16.598  1.00 59.76  ?  6818 MET   B HE2    1 
ATOM   343  H  HE3    . MET   A  1 20  ? 67.256  -36.667 17.539  1.00 59.76  ?  6818 MET   B HE3    1 
ATOM   344  N  N      . LEU   A  1 21  ? 66.399  -32.887 17.791  1.00 49.79  ?  6819 LEU   B N      1 
ATOM   345  C  CA     . LEU   A  1 21  ? 66.690  -31.643 18.485  1.00 48.12  ?  6819 LEU   B CA     1 
ATOM   346  C  C      . LEU   A  1 21  ? 68.152  -31.284 18.282  1.00 41.84  ?  6819 LEU   B C      1 
ATOM   347  O  O      . LEU   A  1 21  ? 69.002  -32.159 18.094  1.00 47.23  ?  6819 LEU   B O      1 
ATOM   348  C  CB     . LEU   A  1 21  ? 66.382  -31.771 19.969  1.00 54.97  ?  6819 LEU   B CB     1 
ATOM   349  C  CG     . LEU   A  1 21  ? 64.899  -32.006 20.232  1.00 62.28  ?  6819 LEU   B CG     1 
ATOM   350  C  CD1    . LEU   A  1 21  ? 64.778  -32.340 21.746  1.00 59.24  ?  6819 LEU   B CD1    1 
ATOM   351  C  CD2    . LEU   A  1 21  ? 64.042  -30.838 19.868  1.00 63.79  ?  6819 LEU   B CD2    1 
ATOM   352  H  H      . LEU   A  1 21  ? 66.739  -33.578 18.173  1.00 60.28  ?  6819 LEU   B H      1 
ATOM   353  H  HA     . LEU   A  1 21  ? 66.146  -30.923 18.128  1.00 58.27  ?  6819 LEU   B HA     1 
ATOM   354  H  HB2    . LEU   A  1 21  ? 66.878  -32.522 20.332  1.00 66.49  ?  6819 LEU   B HB2    1 
ATOM   355  H  HB3    . LEU   A  1 21  ? 66.644  -30.952 20.419  1.00 66.49  ?  6819 LEU   B HB3    1 
ATOM   356  H  HG     . LEU   A  1 21  ? 64.567  -32.729 19.677  1.00 75.26  ?  6819 LEU   B HG     1 
ATOM   357  H  HD11   . LEU   A  1 21  ? 63.841  -32.450 21.971  1.00 71.61  ?  6819 LEU   B HD11   1 
ATOM   358  H  HD12   . LEU   A  1 21  ? 65.261  -33.161 21.927  1.00 71.61  ?  6819 LEU   B HD12   1 
ATOM   359  H  HD13   . LEU   A  1 21  ? 65.159  -31.612 22.261  1.00 71.61  ?  6819 LEU   B HD13   1 
ATOM   360  H  HD21   . LEU   A  1 21  ? 63.136  -31.005 20.171  1.00 77.07  ?  6819 LEU   B HD21   1 
ATOM   361  H  HD22   . LEU   A  1 21  ? 64.394  -30.043 20.297  1.00 77.07  ?  6819 LEU   B HD22   1 
ATOM   362  H  HD23   . LEU   A  1 21  ? 64.053  -30.727 18.905  1.00 77.07  ?  6819 LEU   B HD23   1 
ATOM   363  N  N      . LEU   A  1 22  ? 68.438  -29.985 18.332  1.00 44.76  ?  6820 LEU   B N      1 
ATOM   364  C  CA     . LEU   A  1 22  ? 69.778  -29.505 18.037  1.00 43.19  ?  6820 LEU   B CA     1 
ATOM   365  C  C      . LEU   A  1 22  ? 70.722  -29.903 19.164  1.00 47.13  ?  6820 LEU   B C      1 
ATOM   366  O  O      . LEU   A  1 22  ? 70.495  -29.554 20.327  1.00 56.11  ?  6820 LEU   B O      1 
ATOM   367  C  CB     . LEU   A  1 22  ? 69.793  -27.994 17.865  1.00 42.34  ?  6820 LEU   B CB     1 
ATOM   368  C  CG     . LEU   A  1 22  ? 71.115  -27.407 17.351  1.00 46.84  ?  6820 LEU   B CG     1 
ATOM   369  C  CD1    . LEU   A  1 22  ? 71.640  -28.117 16.132  1.00 46.49  ?  6820 LEU   B CD1    1 
ATOM   370  C  CD2    . LEU   A  1 22  ? 70.942  -25.915 17.124  1.00 42.91  ?  6820 LEU   B CD2    1 
ATOM   371  H  H      . LEU   A  1 22  ? 67.874  -29.367 18.532  1.00 54.23  ?  6820 LEU   B H      1 
ATOM   372  H  HA     . LEU   A  1 22  ? 70.075  -29.908 17.206  1.00 52.35  ?  6820 LEU   B HA     1 
ATOM   373  H  HB2    . LEU   A  1 22  ? 69.101  -27.752 17.230  1.00 51.34  ?  6820 LEU   B HB2    1 
ATOM   374  H  HB3    . LEU   A  1 22  ? 69.610  -27.587 18.726  1.00 51.34  ?  6820 LEU   B HB3    1 
ATOM   375  H  HG     . LEU   A  1 22  ? 71.803  -27.542 18.022  1.00 56.73  ?  6820 LEU   B HG     1 
ATOM   376  H  HD11   . LEU   A  1 22  ? 72.403  -27.629 15.786  1.00 56.31  ?  6820 LEU   B HD11   1 
ATOM   377  H  HD12   . LEU   A  1 22  ? 71.908  -29.016 16.381  1.00 56.31  ?  6820 LEU   B HD12   1 
ATOM   378  H  HD13   . LEU   A  1 22  ? 70.939  -28.154 15.462  1.00 56.31  ?  6820 LEU   B HD13   1 
ATOM   379  H  HD21   . LEU   A  1 22  ? 71.782  -25.543 16.813  1.00 52.02  ?  6820 LEU   B HD21   1 
ATOM   380  H  HD22   . LEU   A  1 22  ? 70.252  -25.775 16.456  1.00 52.02  ?  6820 LEU   B HD22   1 
ATOM   381  H  HD23   . LEU   A  1 22  ? 70.683  -25.496 17.959  1.00 52.02  ?  6820 LEU   B HD23   1 
ATOM   382  N  N      . GLU   A  1 23  ? 71.792  -30.616 18.820  1.00 52.47  ?  6821 GLU   B N      1 
ATOM   383  C  CA     . GLU   A  1 23  ? 72.875  -30.918 19.741  1.00 47.39  ?  6821 GLU   B CA     1 
ATOM   384  C  C      . GLU   A  1 23  ? 74.140  -30.192 19.303  1.00 42.77  ?  6821 GLU   B C      1 
ATOM   385  O  O      . GLU   A  1 23  ? 74.225  -29.631 18.206  1.00 51.94  ?  6821 GLU   B O      1 
ATOM   386  C  CB     . GLU   A  1 23  ? 73.154  -32.424 19.802  1.00 49.53  ?  6821 GLU   B CB     1 
ATOM   387  C  CG     . GLU   A  1 23  ? 71.985  -33.319 20.139  1.00 61.49  ?  6821 GLU   B CG     1 
ATOM   388  C  CD     . GLU   A  1 23  ? 72.431  -34.730 20.418  1.00 74.89  ?  6821 GLU   B CD     1 
ATOM   389  O  OE1    . GLU   A  1 23  ? 73.387  -34.924 21.185  1.00 78.73  ?  6821 GLU   B OE1    1 
ATOM   390  O  OE2    . GLU   A  1 23  ? 71.844  -35.662 19.851  1.00 77.62  ?  6821 GLU   B OE2    1 
ATOM   391  H  H      . GLU   A  1 23  ? 71.913  -30.943 18.034  1.00 63.49  ?  6821 GLU   B H      1 
ATOM   392  H  HA     . GLU   A  1 23  ? 72.619  -30.618 20.627  1.00 57.39  ?  6821 GLU   B HA     1 
ATOM   393  H  HB2    . GLU   A  1 23  ? 73.484  -32.704 18.934  1.00 59.96  ?  6821 GLU   B HB2    1 
ATOM   394  H  HB3    . GLU   A  1 23  ? 73.832  -32.577 20.479  1.00 59.96  ?  6821 GLU   B HB3    1 
ATOM   395  H  HG2    . GLU   A  1 23  ? 71.539  -32.978 20.930  1.00 74.31  ?  6821 GLU   B HG2    1 
ATOM   396  H  HG3    . GLU   A  1 23  ? 71.368  -33.335 19.391  1.00 74.31  ?  6821 GLU   B HG3    1 
ATOM   397  N  N      . LYS   A  1 24  ? 75.139  -30.225 20.183  1.00 43.49  ?  6822 LYS   B N      1 
ATOM   398  C  CA     . LYS   A  1 24  ? 76.492  -29.834 19.806  1.00 41.44  ?  6822 LYS   B CA     1 
ATOM   399  C  C      . LYS   A  1 24  ? 77.048  -30.834 18.788  1.00 45.04  ?  6822 LYS   B C      1 
ATOM   400  O  O      . LYS   A  1 24  ? 76.748  -32.032 18.835  1.00 47.22  ?  6822 LYS   B O      1 
ATOM   401  C  CB     . LYS   A  1 24  ? 77.392  -29.780 21.050  1.00 48.67  ?  6822 LYS   B CB     1 
ATOM   402  C  CG     . LYS   A  1 24  ? 78.874  -29.457 20.766  1.00 70.78  ?  6822 LYS   B CG     1 
ATOM   403  C  CD     . LYS   A  1 24  ? 79.539  -28.740 21.915  1.00 66.04  ?  6822 LYS   B CD     1 
ATOM   404  C  CE     . LYS   A  1 24  ? 81.064  -28.791 21.786  1.00 70.12  ?  6822 LYS   B CE     1 
ATOM   405  N  NZ     . LYS   A  1 24  ? 81.591  -29.936 21.045  1.00 80.08  ?  6822 LYS   B NZ     1 
ATOM   406  H  H      . LYS   A  1 24  ? 75.058  -30.470 21.003  1.00 52.71  ?  6822 LYS   B H      1 
ATOM   407  H  HA     . LYS   A  1 24  ? 76.492  -28.951 19.405  1.00 50.25  ?  6822 LYS   B HA     1 
ATOM   408  H  HB2    . LYS   A  1 24  ? 77.053  -29.093 21.645  1.00 58.92  ?  6822 LYS   B HB2    1 
ATOM   409  H  HB3    . LYS   A  1 24  ? 77.361  -30.644 21.490  1.00 58.92  ?  6822 LYS   B HB3    1 
ATOM   410  H  HG2    . LYS   A  1 24  ? 79.355  -30.285 20.610  1.00 85.45  ?  6822 LYS   B HG2    1 
ATOM   411  H  HG3    . LYS   A  1 24  ? 78.931  -28.888 19.983  1.00 85.45  ?  6822 LYS   B HG3    1 
ATOM   412  H  HD2    . LYS   A  1 24  ? 79.262  -27.810 21.919  1.00 79.76  ?  6822 LYS   B HD2    1 
ATOM   413  H  HD3    . LYS   A  1 24  ? 79.287  -29.165 22.750  1.00 79.76  ?  6822 LYS   B HD3    1 
ATOM   414  H  HE2    . LYS   A  1 24  ? 81.360  -27.989 21.327  1.00 84.67  ?  6822 LYS   B HE2    1 
ATOM   415  H  HE3    . LYS   A  1 24  ? 81.446  -28.822 22.677  1.00 84.67  ?  6822 LYS   B HE3    1 
ATOM   416  H  HZ1    . LYS   A  1 24  ? 82.480  -29.905 21.027  1.00 96.62  ?  6822 LYS   B HZ1    1 
ATOM   417  H  HZ2    . LYS   A  1 24  ? 81.336  -30.695 21.436  1.00 96.62  ?  6822 LYS   B HZ2    1 
ATOM   418  H  HZ3    . LYS   A  1 24  ? 81.284  -29.925 20.209  1.00 96.62  ?  6822 LYS   B HZ3    1 
ATOM   419  N  N      . CYS   A  1 25  ? 77.852  -30.342 17.847  1.00 47.85  ?  6823 CYS   B N      1 
ATOM   420  C  CA     . CYS   A  1 25  ? 78.425  -31.217 16.835  1.00 39.60  ?  6823 CYS   B CA     1 
ATOM   421  C  C      . CYS   A  1 25  ? 79.758  -31.735 17.379  1.00 37.82  ?  6823 CYS   B C      1 
ATOM   422  O  O      . CYS   A  1 25  ? 80.622  -30.947 17.777  1.00 41.69  ?  6823 CYS   B O      1 
ATOM   423  C  CB     . CYS   A  1 25  ? 78.608  -30.491 15.494  1.00 40.91  ?  6823 CYS   B CB     1 
ATOM   424  S  SG     . CYS   A  1 25  ? 79.358  -31.549 14.203  1.00 43.55  ?  6823 CYS   B SG     1 
ATOM   425  H  H      . CYS   A  1 25  ? 78.076  -29.514 17.777  1.00 57.94  ?  6823 CYS   B H      1 
ATOM   426  H  HA     . CYS   A  1 25  ? 77.833  -31.965 16.663  1.00 48.04  ?  6823 CYS   B HA     1 
ATOM   427  H  HB2    . CYS   A  1 25  ? 77.741  -30.197 15.174  1.00 49.62  ?  6823 CYS   B HB2    1 
ATOM   428  H  HB3    . CYS   A  1 25  ? 79.189  -29.725 15.628  1.00 49.62  ?  6823 CYS   B HB3    1 
ATOM   429  H  HG     . CYS   A  1 25  ? 79.453  -30.917 13.187  1.00 52.78  ?  6823 CYS   B HG     1 
ATOM   430  N  N      . ASP   A  1 26  ? 79.899  -33.060 17.430  1.00 45.39  ?  6824 ASP   B N      1 
ATOM   431  C  CA     . ASP   A  1 26  ? 81.084  -33.759 17.924  1.00 49.68  ?  6824 ASP   B CA     1 
ATOM   432  C  C      . ASP   A  1 26  ? 81.510  -34.731 16.832  1.00 44.20  ?  6824 ASP   B C      1 
ATOM   433  O  O      . ASP   A  1 26  ? 80.887  -35.782 16.653  1.00 46.05  ?  6824 ASP   B O      1 
ATOM   434  C  CB     . ASP   A  1 26  ? 80.785  -34.472 19.246  1.00 51.50  ?  6824 ASP   B CB     1 
ATOM   435  C  CG     . ASP   A  1 26  ? 81.972  -35.269 19.788  1.00 53.97  ?  6824 ASP   B CG     1 
ATOM   436  O  OD1    . ASP   A  1 26  ? 83.048  -35.291 19.149  1.00 54.38  ?  6824 ASP   B OD1    1 
ATOM   437  O  OD2    . ASP   A  1 26  ? 81.828  -35.854 20.886  1.00 64.39  ?  6824 ASP   B OD2    1 
ATOM   438  H  H      . ASP   A  1 26  ? 79.287  -33.604 17.169  1.00 55.00  ?  6824 ASP   B H      1 
ATOM   439  H  HA     . ASP   A  1 26  ? 81.808  -33.133 18.082  1.00 60.13  ?  6824 ASP   B HA     1 
ATOM   440  H  HB2    . ASP   A  1 26  ? 80.542  -33.810 19.912  1.00 62.32  ?  6824 ASP   B HB2    1 
ATOM   441  H  HB3    . ASP   A  1 26  ? 80.050  -35.090 19.110  1.00 62.32  ?  6824 ASP   B HB3    1 
ATOM   442  N  N      . LEU   A  1 27  ? 82.568  -34.370 16.110  1.00 51.14  ?  6825 LEU   B N      1 
ATOM   443  C  CA     . LEU   A  1 27  ? 83.113  -35.169 15.023  1.00 49.94  ?  6825 LEU   B CA     1 
ATOM   444  C  C      . LEU   A  1 27  ? 84.339  -35.899 15.552  1.00 50.12  ?  6825 LEU   B C      1 
ATOM   445  O  O      . LEU   A  1 27  ? 85.260  -35.259 16.072  1.00 53.44  ?  6825 LEU   B O      1 
ATOM   446  C  CB     . LEU   A  1 27  ? 83.499  -34.290 13.829  1.00 43.81  ?  6825 LEU   B CB     1 
ATOM   447  C  CG     . LEU   A  1 27  ? 82.366  -33.500 13.187  1.00 43.49  ?  6825 LEU   B CG     1 
ATOM   448  C  CD1    . LEU   A  1 27  ? 82.828  -32.753 11.950  1.00 44.70  ?  6825 LEU   B CD1    1 
ATOM   449  C  CD2    . LEU   A  1 27  ? 81.214  -34.442 12.807  1.00 42.16  ?  6825 LEU   B CD2    1 
ATOM   450  H  H      . LEU   A  1 27  ? 83.001  -33.638 16.238  1.00 61.89  ?  6825 LEU   B H      1 
ATOM   451  H  HA     . LEU   A  1 27  ? 82.452  -35.812 14.723  1.00 60.44  ?  6825 LEU   B HA     1 
ATOM   452  H  HB2    . LEU   A  1 27  ? 84.163  -33.649 14.128  1.00 53.09  ?  6825 LEU   B HB2    1 
ATOM   453  H  HB3    . LEU   A  1 27  ? 83.876  -34.862 13.142  1.00 53.09  ?  6825 LEU   B HB3    1 
ATOM   454  H  HG     . LEU   A  1 27  ? 82.057  -32.845 13.832  1.00 52.71  ?  6825 LEU   B HG     1 
ATOM   455  H  HD11   . LEU   A  1 27  ? 82.097  -32.207 11.620  1.00 54.16  ?  6825 LEU   B HD11   1 
ATOM   456  H  HD12   . LEU   A  1 27  ? 83.582  -32.190 12.184  1.00 54.16  ?  6825 LEU   B HD12   1 
ATOM   457  H  HD13   . LEU   A  1 27  ? 83.092  -33.396 11.274  1.00 54.16  ?  6825 LEU   B HD13   1 
ATOM   458  H  HD21   . LEU   A  1 27  ? 80.568  -33.952 12.275  1.00 51.12  ?  6825 LEU   B HD21   1 
ATOM   459  H  HD22   . LEU   A  1 27  ? 81.570  -35.185 12.295  1.00 51.12  ?  6825 LEU   B HD22   1 
ATOM   460  H  HD23   . LEU   A  1 27  ? 80.795  -34.770 13.618  1.00 51.12  ?  6825 LEU   B HD23   1 
ATOM   461  N  N      . GLN   A  1 28  ? 84.354  -37.227 15.420  1.00 55.05  ?  6826 GLN   B N      1 
ATOM   462  C  CA     . GLN   A  1 28  ? 85.450  -38.015 15.979  1.00 60.60  ?  6826 GLN   B CA     1 
ATOM   463  C  C      . GLN   A  1 28  ? 86.778  -37.730 15.286  1.00 63.40  ?  6826 GLN   B C      1 
ATOM   464  O  O      . GLN   A  1 28  ? 87.822  -37.755 15.944  1.00 70.08  ?  6826 GLN   B O      1 
ATOM   465  C  CB     . GLN   A  1 28  ? 85.083  -39.504 15.933  1.00 61.10  ?  6826 GLN   B CB     1 
ATOM   466  C  CG     . GLN   A  1 28  ? 85.283  -40.203 14.607  1.00 81.19  ?  6826 GLN   B CG     1 
ATOM   467  C  CD     . GLN   A  1 28  ? 84.759  -41.627 14.624  1.00 83.32  ?  6826 GLN   B CD     1 
ATOM   468  O  OE1    . GLN   A  1 28  ? 85.331  -42.516 14.011  1.00 73.71  ?  6826 GLN   B OE1    1 
ATOM   469  N  NE2    . GLN   A  1 28  ? 83.661  -41.844 15.327  1.00 74.02  ?  6826 GLN   B NE2    1 
ATOM   470  H  H      . GLN   A  1 28  ? 83.751  -37.689 15.016  1.00 66.58  ?  6826 GLN   B H      1 
ATOM   471  H  HA     . GLN   A  1 28  ? 85.577  -37.775 16.910  1.00 73.24  ?  6826 GLN   B HA     1 
ATOM   472  H  HB2    . GLN   A  1 28  ? 85.629  -39.970 16.586  1.00 73.84  ?  6826 GLN   B HB2    1 
ATOM   473  H  HB3    . GLN   A  1 28  ? 84.145  -39.591 16.163  1.00 73.84  ?  6826 GLN   B HB3    1 
ATOM   474  H  HG2    . GLN   A  1 28  ? 84.809  -39.715 13.915  1.00 97.95  ?  6826 GLN   B HG2    1 
ATOM   475  H  HG3    . GLN   A  1 28  ? 86.231  -40.232 14.402  1.00 97.95  ?  6826 GLN   B HG3    1 
ATOM   476  H  HE21   . GLN   A  1 28  ? 83.283  -41.194 15.744  1.00 89.35  ?  6826 GLN   B HE21   1 
ATOM   477  H  HE22   . GLN   A  1 28  ? 83.326  -42.635 15.367  1.00 89.35  ?  6826 GLN   B HE22   1 
ATOM   478  N  N      . ASN   A  1 29  ? 86.773  -37.430 13.986  1.00 60.14  ?  6827 ASN   B N      1 
ATOM   479  C  CA     . ASN   A  1 29  ? 88.001  -37.069 13.289  1.00 65.14  ?  6827 ASN   B CA     1 
ATOM   480  C  C      . ASN   A  1 29  ? 88.279  -35.573 13.321  1.00 61.14  ?  6827 ASN   B C      1 
ATOM   481  O  O      . ASN   A  1 29  ? 89.111  -35.090 12.544  1.00 55.40  ?  6827 ASN   B O      1 
ATOM   482  C  CB     . ASN   A  1 29  ? 87.971  -37.569 11.844  1.00 59.77  ?  6827 ASN   B CB     1 
ATOM   483  C  CG     . ASN   A  1 29  ? 86.768  -37.075 11.077  1.00 65.48  ?  6827 ASN   B CG     1 
ATOM   484  O  OD1    . ASN   A  1 29  ? 85.973  -36.290 11.571  1.00 67.18  ?  6827 ASN   B OD1    1 
ATOM   485  N  ND2    . ASN   A  1 29  ? 86.636  -37.528 9.853   1.00 60.44  ?  6827 ASN   B ND2    1 
ATOM   486  H  H      . ASN   A  1 29  ? 86.070  -37.428 13.491  1.00 72.69  ?  6827 ASN   B H      1 
ATOM   487  H  HA     . ASN   A  1 29  ? 88.737  -37.517 13.735  1.00 78.69  ?  6827 ASN   B HA     1 
ATOM   488  H  HB2    . ASN   A  1 29  ? 88.767  -37.256 11.385  1.00 72.24  ?  6827 ASN   B HB2    1 
ATOM   489  H  HB3    . ASN   A  1 29  ? 87.949  -38.538 11.845  1.00 72.24  ?  6827 ASN   B HB3    1 
ATOM   490  H  HD21   . ASN   A  1 29  ? 85.968  -37.279 9.372   1.00 73.04  ?  6827 ASN   B HD21   1 
ATOM   491  H  HD22   . ASN   A  1 29  ? 87.217  -38.075 9.531   1.00 73.04  ?  6827 ASN   B HD22   1 
ATOM   492  N  N      . TYR   A  1 30  ? 87.624  -34.837 14.216  1.00 53.91  ?  6828 TYR   B N      1 
ATOM   493  C  CA     . TYR   A  1 30  ? 87.884  -33.412 14.337  1.00 55.92  ?  6828 TYR   B CA     1 
ATOM   494  C  C      . TYR   A  1 30  ? 89.365  -33.119 14.500  1.00 65.34  ?  6828 TYR   B C      1 
ATOM   495  O  O      . TYR   A  1 30  ? 90.038  -33.701 15.355  1.00 70.09  ?  6828 TYR   B O      1 
ATOM   496  C  CB     . TYR   A  1 30  ? 87.139  -32.828 15.527  1.00 57.46  ?  6828 TYR   B CB     1 
ATOM   497  C  CG     . TYR   A  1 30  ? 87.233  -31.333 15.567  1.00 59.09  ?  6828 TYR   B CG     1 
ATOM   498  C  CD1    . TYR   A  1 30  ? 86.542  -30.574 14.647  1.00 65.68  ?  6828 TYR   B CD1    1 
ATOM   499  C  CD2    . TYR   A  1 30  ? 88.043  -30.680 16.492  1.00 61.57  ?  6828 TYR   B CD2    1 
ATOM   500  C  CE1    . TYR   A  1 30  ? 86.620  -29.206 14.651  1.00 76.40  ?  6828 TYR   B CE1    1 
ATOM   501  C  CE2    . TYR   A  1 30  ? 88.128  -29.290 16.508  1.00 67.90  ?  6828 TYR   B CE2    1 
ATOM   502  C  CZ     . TYR   A  1 30  ? 87.408  -28.567 15.578  1.00 74.69  ?  6828 TYR   B CZ     1 
ATOM   503  O  OH     . TYR   A  1 30  ? 87.465  -27.199 15.552  1.00 76.65  ?  6828 TYR   B OH     1 
ATOM   504  H  H      . TYR   A  1 30  ? 87.030  -35.139 14.760  1.00 65.21  ?  6828 TYR   B H      1 
ATOM   505  H  HA     . TYR   A  1 30  ? 87.569  -32.989 13.523  1.00 67.62  ?  6828 TYR   B HA     1 
ATOM   506  H  HB2    . TYR   A  1 30  ? 86.202  -33.073 15.468  1.00 69.47  ?  6828 TYR   B HB2    1 
ATOM   507  H  HB3    . TYR   A  1 30  ? 87.522  -33.179 16.346  1.00 69.47  ?  6828 TYR   B HB3    1 
ATOM   508  H  HD1    . TYR   A  1 30  ? 86.012  -30.998 14.011  1.00 79.34  ?  6828 TYR   B HD1    1 
ATOM   509  H  HD2    . TYR   A  1 30  ? 88.533  -31.178 17.106  1.00 74.40  ?  6828 TYR   B HD2    1 
ATOM   510  H  HE1    . TYR   A  1 30  ? 86.140  -28.711 14.027  1.00 92.20  ?  6828 TYR   B HE1    1 
ATOM   511  H  HE2    . TYR   A  1 30  ? 88.661  -28.856 17.135  1.00 82.01  ?  6828 TYR   B HE2    1 
ATOM   512  H  HH     . TYR   A  1 30  ? 87.950  -26.920 16.179  1.00 92.51  ?  6828 TYR   B HH     1 
ATOM   513  N  N      . GLY   A  1 31  ? 89.861  -32.180 13.702  1.00 68.76  ?  6829 GLY   B N      1 
ATOM   514  C  CA     . GLY   A  1 31  ? 91.248  -31.799 13.752  1.00 68.68  ?  6829 GLY   B CA     1 
ATOM   515  C  C      . GLY   A  1 31  ? 92.136  -32.538 12.783  1.00 66.60  ?  6829 GLY   B C      1 
ATOM   516  O  O      . GLY   A  1 31  ? 93.194  -32.018 12.421  1.00 62.63  ?  6829 GLY   B O      1 
ATOM   517  H  H      . GLY   A  1 31  ? 89.399  -31.748 13.119  1.00 83.04  ?  6829 GLY   B H      1 
ATOM   518  H  HA2    . GLY   A  1 31  ? 91.318  -30.851 13.556  1.00 82.94  ?  6829 GLY   B HA2    1 
ATOM   519  H  HA3    . GLY   A  1 31  ? 91.584  -31.962 14.648  1.00 82.94  ?  6829 GLY   B HA3    1 
ATOM   520  N  N      . ASP   A  1 32  ? 91.752  -33.750 12.383  1.00 65.87  ?  6830 ASP   B N      1 
ATOM   521  C  CA     . ASP   A  1 32  ? 92.469  -34.436 11.320  1.00 68.83  ?  6830 ASP   B CA     1 
ATOM   522  C  C      . ASP   A  1 32  ? 92.408  -33.631 10.023  1.00 56.91  ?  6830 ASP   B C      1 
ATOM   523  O  O      . ASP   A  1 32  ? 91.499  -32.830 9.793   1.00 58.72  ?  6830 ASP   B O      1 
ATOM   524  C  CB     . ASP   A  1 32  ? 91.882  -35.829 11.082  1.00 63.39  ?  6830 ASP   B CB     1 
ATOM   525  C  CG     . ASP   A  1 32  ? 91.993  -36.729 12.288  1.00 66.61  ?  6830 ASP   B CG     1 
ATOM   526  O  OD1    . ASP   A  1 32  ? 92.656  -36.344 13.265  1.00 66.14  ?  6830 ASP   B OD1    1 
ATOM   527  O  OD2    . ASP   A  1 32  ? 91.437  -37.845 12.252  1.00 58.51  ?  6830 ASP   B OD2    1 
ATOM   528  H  H      . ASP   A  1 32  ? 91.087  -34.188 12.709  1.00 79.57  ?  6830 ASP   B H      1 
ATOM   529  H  HA     . ASP   A  1 32  ? 93.398  -34.536 11.580  1.00 83.11  ?  6830 ASP   B HA     1 
ATOM   530  H  HB2    . ASP   A  1 32  ? 90.942  -35.742 10.860  1.00 76.59  ?  6830 ASP   B HB2    1 
ATOM   531  H  HB3    . ASP   A  1 32  ? 92.359  -36.251 10.350  1.00 76.59  ?  6830 ASP   B HB3    1 
ATOM   532  N  N      . SER   A  1 33  ? 93.390  -33.865 9.164   1.00 62.18  ?  6831 SER   B N      1 
ATOM   533  C  CA     . SER   A  1 33  ? 93.431  -33.265 7.840   1.00 53.42  ?  6831 SER   B CA     1 
ATOM   534  C  C      . SER   A  1 33  ? 93.693  -34.357 6.814   1.00 53.33  ?  6831 SER   B C      1 
ATOM   535  O  O      . SER   A  1 33  ? 94.412  -35.325 7.078   1.00 59.10  ?  6831 SER   B O      1 
ATOM   536  C  CB     . SER   A  1 33  ? 94.509  -32.163 7.747   1.00 57.53  ?  6831 SER   B CB     1 
ATOM   537  O  OG     . SER   A  1 33  ? 94.140  -31.044 8.539   1.00 56.89  ?  6831 SER   B OG     1 
ATOM   538  H  H      . SER   A  1 33  ? 94.058  -34.380 9.329   1.00 75.14  ?  6831 SER   B H      1 
ATOM   539  H  HA     . SER   A  1 33  ? 92.579  -32.851 7.633   1.00 64.63  ?  6831 SER   B HA     1 
ATOM   540  H  HB2    . SER   A  1 33  ? 95.353  -32.516 8.069   1.00 69.56  ?  6831 SER   B HB2    1 
ATOM   541  H  HB3    . SER   A  1 33  ? 94.598  -31.883 6.822   1.00 69.56  ?  6831 SER   B HB3    1 
ATOM   542  H  HG     . SER   A  1 33  ? 94.723  -30.443 8.476   1.00 68.79  ?  6831 SER   B HG     1 
ATOM   543  N  N      . ALA   A  1 34  ? 93.082  -34.206 5.646   1.00 57.72  ?  6832 ALA   B N      1 
ATOM   544  C  CA     . ALA   A  1 34  ? 93.355  -35.106 4.546   1.00 54.73  ?  6832 ALA   B CA     1 
ATOM   545  C  C      . ALA   A  1 34  ? 94.697  -34.755 3.923   1.00 47.93  ?  6832 ALA   B C      1 
ATOM   546  O  O      . ALA   A  1 34  ? 95.214  -33.646 4.077   1.00 50.43  ?  6832 ALA   B O      1 
ATOM   547  C  CB     . ALA   A  1 34  ? 92.255  -35.020 3.496   1.00 52.08  ?  6832 ALA   B CB     1 
ATOM   548  H  H      . ALA   A  1 34  ? 92.507  -33.591 5.470   1.00 69.78  ?  6832 ALA   B H      1 
ATOM   549  H  HA     . ALA   A  1 34  ? 93.386  -36.021 4.867   1.00 66.20  ?  6832 ALA   B HA     1 
ATOM   550  H  HB1    . ALA   A  1 34  ? 92.465  -35.626 2.768   1.00 63.01  ?  6832 ALA   B HB1    1 
ATOM   551  H  HB2    . ALA   A  1 34  ? 91.410  -35.270 3.902   1.00 63.01  ?  6832 ALA   B HB2    1 
ATOM   552  H  HB3    . ALA   A  1 34  ? 92.206  -34.110 3.164   1.00 63.01  ?  6832 ALA   B HB3    1 
ATOM   553  N  N      . THR   A  1 35  ? 95.276  -35.727 3.226   1.00 55.07  ?  6833 THR   B N      1 
ATOM   554  C  CA     . THR   A  1 35  ? 96.541  -35.507 2.536   1.00 50.72  ?  6833 THR   B CA     1 
ATOM   555  C  C      . THR   A  1 35  ? 96.245  -35.002 1.129   1.00 38.86  ?  6833 THR   B C      1 
ATOM   556  O  O      . THR   A  1 35  ? 95.823  -35.755 0.255   1.00 50.30  ?  6833 THR   B O      1 
ATOM   557  C  CB     . THR   A  1 35  ? 97.388  -36.770 2.516   1.00 51.07  ?  6833 THR   B CB     1 
ATOM   558  O  OG1    . THR   A  1 35  ? 97.918  -37.002 3.831   1.00 65.52  ?  6833 THR   B OG1    1 
ATOM   559  C  CG2    . THR   A  1 35  ? 98.546  -36.593 1.523   1.00 58.35  ?  6833 THR   B CG2    1 
ATOM   560  H  H      . THR   A  1 35  ? 94.956  -36.520 3.139   1.00 66.60  ?  6833 THR   B H      1 
ATOM   561  H  HA     . THR   A  1 35  ? 97.047  -34.825 3.005   1.00 61.39  ?  6833 THR   B HA     1 
ATOM   562  H  HB     . THR   A  1 35  ? 96.855  -37.534 2.245   1.00 61.81  ?  6833 THR   B HB     1 
ATOM   563  H  HG1    . THR   A  1 35  ? 98.361  -37.715 3.841   1.00 79.14  ?  6833 THR   B HG1    1 
ATOM   564  H  HG21   . THR   A  1 35  ? 99.245  -37.240 1.709   1.00 70.54  ?  6833 THR   B HG21   1 
ATOM   565  H  HG22   . THR   A  1 35  ? 98.228  -36.725 0.616   1.00 70.54  ?  6833 THR   B HG22   1 
ATOM   566  H  HG23   . THR   A  1 35  ? 98.915  -35.699 1.600   1.00 70.54  ?  6833 THR   B HG23   1 
ATOM   567  N  N      . LEU   A  1 36  ? 96.431  -33.721 0.933   1.00 45.56  ?  6834 LEU   B N      1 
ATOM   568  C  CA     . LEU   A  1 36  ? 96.198  -33.096 -0.352  1.00 44.52  ?  6834 LEU   B CA     1 
ATOM   569  C  C      . LEU   A  1 36  ? 97.353  -33.381 -1.304  1.00 39.32  ?  6834 LEU   B C      1 
ATOM   570  O  O      . LEU   A  1 36  ? 98.501  -33.511 -0.878  1.00 41.34  ?  6834 LEU   B O      1 
ATOM   571  C  CB     . LEU   A  1 36  ? 96.053  -31.598 -0.162  1.00 44.11  ?  6834 LEU   B CB     1 
ATOM   572  C  CG     . LEU   A  1 36  ? 94.914  -31.176 0.755   1.00 44.52  ?  6834 LEU   B CG     1 
ATOM   573  C  CD1    . LEU   A  1 36  ? 94.958  -29.672 0.980   1.00 43.21  ?  6834 LEU   B CD1    1 
ATOM   574  C  CD2    . LEU   A  1 36  ? 93.605  -31.575 0.120   1.00 50.16  ?  6834 LEU   B CD2    1 
ATOM   575  H  H      . LEU   A  1 36  ? 96.698  -33.172 1.539   1.00 55.19  ?  6834 LEU   B H      1 
ATOM   576  H  HA     . LEU   A  1 36  ? 95.386  -33.446 -0.753  1.00 53.94  ?  6834 LEU   B HA     1 
ATOM   577  H  HB2    . LEU   A  1 36  ? 96.877  -31.256 0.218   1.00 53.45  ?  6834 LEU   B HB2    1 
ATOM   578  H  HB3    . LEU   A  1 36  ? 95.894  -31.193 -1.029  1.00 53.45  ?  6834 LEU   B HB3    1 
ATOM   579  H  HG     . LEU   A  1 36  ? 94.995  -31.611 1.619   1.00 53.94  ?  6834 LEU   B HG     1 
ATOM   580  H  HD11   . LEU   A  1 36  ? 94.256  -29.425 1.602   1.00 52.37  ?  6834 LEU   B HD11   1 
ATOM   581  H  HD12   . LEU   A  1 36  ? 95.824  -29.433 1.347   1.00 52.37  ?  6834 LEU   B HD12   1 
ATOM   582  H  HD13   . LEU   A  1 36  ? 94.822  -29.222 0.132   1.00 52.37  ?  6834 LEU   B HD13   1 
ATOM   583  H  HD21   . LEU   A  1 36  ? 92.878  -31.142 0.594   1.00 60.72  ?  6834 LEU   B HD21   1 
ATOM   584  H  HD22   . LEU   A  1 36  ? 93.606  -31.296 -0.809  1.00 60.72  ?  6834 LEU   B HD22   1 
ATOM   585  H  HD23   . LEU   A  1 36  ? 93.507  -32.539 0.175   1.00 60.72  ?  6834 LEU   B HD23   1 
ATOM   586  N  N      . PRO   A  1 37  ? 97.061  -33.500 -2.595  1.00 45.93  ?  6835 PRO   B N      1 
ATOM   587  C  CA     . PRO   A  1 37  ? 98.135  -33.619 -3.584  1.00 42.07  ?  6835 PRO   B CA     1 
ATOM   588  C  C      . PRO   A  1 37  ? 99.143  -32.493 -3.410  1.00 40.82  ?  6835 PRO   B C      1 
ATOM   589  O  O      . PRO   A  1 37  ? 98.818  -31.412 -2.917  1.00 46.04  ?  6835 PRO   B O      1 
ATOM   590  C  CB     . PRO   A  1 37  ? 97.400  -33.537 -4.923  1.00 39.92  ?  6835 PRO   B CB     1 
ATOM   591  C  CG     . PRO   A  1 37  ? 95.979  -33.956 -4.610  1.00 39.97  ?  6835 PRO   B CG     1 
ATOM   592  C  CD     . PRO   A  1 37  ? 95.719  -33.470 -3.208  1.00 39.36  ?  6835 PRO   B CD     1 
ATOM   593  H  HA     . PRO   A  1 37  ? 98.584  -34.477 -3.523  1.00 51.00  ?  6835 PRO   B HA     1 
ATOM   594  H  HB2    . PRO   A  1 37  ? 97.428  -32.628 -5.261  1.00 48.42  ?  6835 PRO   B HB2    1 
ATOM   595  H  HB3    . PRO   A  1 37  ? 97.808  -34.141 -5.563  1.00 48.42  ?  6835 PRO   B HB3    1 
ATOM   596  H  HG2    . PRO   A  1 37  ? 95.367  -33.542 -5.238  1.00 48.49  ?  6835 PRO   B HG2    1 
ATOM   597  H  HG3    . PRO   A  1 37  ? 95.902  -34.922 -4.660  1.00 48.49  ?  6835 PRO   B HG3    1 
ATOM   598  H  HD2    . PRO   A  1 37  ? 95.361  -32.569 -3.214  1.00 47.76  ?  6835 PRO   B HD2    1 
ATOM   599  H  HD3    . PRO   A  1 37  ? 95.112  -34.065 -2.741  1.00 47.76  ?  6835 PRO   B HD3    1 
ATOM   600  N  N      . LYS   A  1 38  ? 100.377 -32.761 -3.833  1.00 45.69  ?  6836 LYS   B N      1 
ATOM   601  C  CA     . LYS   A  1 38  ? 101.469 -31.816 -3.658  1.00 47.64  ?  6836 LYS   B CA     1 
ATOM   602  C  C      . LYS   A  1 38  ? 101.076 -30.451 -4.204  1.00 46.14  ?  6836 LYS   B C      1 
ATOM   603  O  O      . LYS   A  1 38  ? 100.624 -30.326 -5.347  1.00 43.68  ?  6836 LYS   B O      1 
ATOM   604  C  CB     . LYS   A  1 38  ? 102.722 -32.348 -4.366  1.00 53.51  ?  6836 LYS   B CB     1 
ATOM   605  C  CG     . LYS   A  1 38  ? 103.988 -31.524 -4.160  1.00 55.22  ?  6836 LYS   B CG     1 
ATOM   606  C  CD     . LYS   A  1 38  ? 105.212 -32.170 -4.854  1.00 58.27  ?  6836 LYS   B CD     1 
ATOM   607  C  CE     . LYS   A  1 38  ? 106.052 -31.171 -5.632  1.00 73.74  ?  6836 LYS   B CE     1 
ATOM   608  N  NZ     . LYS   A  1 38  ? 106.816 -30.224 -4.809  1.00 89.23  ?  6836 LYS   B NZ     1 
ATOM   609  H  H      . LYS   A  1 38  ? 100.606 -33.490 -4.228  1.00 55.35  ?  6836 LYS   B H      1 
ATOM   610  H  HA     . LYS   A  1 38  ? 101.676 -31.715 -2.716  1.00 57.69  ?  6836 LYS   B HA     1 
ATOM   611  H  HB2    . LYS   A  1 38  ? 102.902 -33.243 -4.036  1.00 64.73  ?  6836 LYS   B HB2    1 
ATOM   612  H  HB3    . LYS   A  1 38  ? 102.546 -32.375 -5.319  1.00 64.73  ?  6836 LYS   B HB3    1 
ATOM   613  H  HG2    . LYS   A  1 38  ? 103.859 -30.639 -4.535  1.00 66.78  ?  6836 LYS   B HG2    1 
ATOM   614  H  HG3    . LYS   A  1 38  ? 104.177 -31.459 -3.211  1.00 66.78  ?  6836 LYS   B HG3    1 
ATOM   615  H  HD2    . LYS   A  1 38  ? 105.779 -32.575 -4.179  1.00 70.44  ?  6836 LYS   B HD2    1 
ATOM   616  H  HD3    . LYS   A  1 38  ? 104.901 -32.846 -5.476  1.00 70.44  ?  6836 LYS   B HD3    1 
ATOM   617  H  HE2    . LYS   A  1 38  ? 106.689 -31.663 -6.174  1.00 89.02  ?  6836 LYS   B HE2    1 
ATOM   618  H  HE3    . LYS   A  1 38  ? 105.463 -30.652 -6.200  1.00 89.02  ?  6836 LYS   B HE3    1 
ATOM   619  H  HZ1    . LYS   A  1 38  ? 107.283 -29.675 -5.332  1.00 107.59 ?  6836 LYS   B HZ1    1 
ATOM   620  H  HZ2    . LYS   A  1 38  ? 106.262 -29.742 -4.307  1.00 107.59 ?  6836 LYS   B HZ2    1 
ATOM   621  H  HZ3    . LYS   A  1 38  ? 107.377 -30.665 -4.278  1.00 107.59 ?  6836 LYS   B HZ3    1 
ATOM   622  N  N      . GLY   A  1 39  ? 101.215 -29.436 -3.352  1.00 45.53  ?  6837 GLY   B N      1 
ATOM   623  C  CA     . GLY   A  1 39  ? 101.023 -28.057 -3.751  1.00 45.60  ?  6837 GLY   B CA     1 
ATOM   624  C  C      . GLY   A  1 39  ? 99.594  -27.617 -3.932  1.00 42.33  ?  6837 GLY   B C      1 
ATOM   625  O  O      . GLY   A  1 39  ? 99.366  -26.506 -4.406  1.00 46.20  ?  6837 GLY   B O      1 
ATOM   626  H  H      . GLY   A  1 39  ? 101.424 -29.527 -2.523  1.00 55.16  ?  6837 GLY   B H      1 
ATOM   627  H  HA2    . GLY   A  1 39  ? 101.421 -27.485 -3.076  1.00 55.24  ?  6837 GLY   B HA2    1 
ATOM   628  H  HA3    . GLY   A  1 39  ? 101.480 -27.916 -4.595  1.00 55.24  ?  6837 GLY   B HA3    1 
ATOM   629  N  N      . ILE   A  1 40  ? 98.624  -28.437 -3.586  1.00 45.27  ?  6838 ILE   B N      1 
ATOM   630  C  CA     . ILE   A  1 40  ? 97.225  -28.119 -3.815  1.00 48.99  ?  6838 ILE   B CA     1 
ATOM   631  C  C      . ILE   A  1 40  ? 96.629  -27.508 -2.550  1.00 41.88  ?  6838 ILE   B C      1 
ATOM   632  O  O      . ILE   A  1 40  ? 96.745  -28.076 -1.458  1.00 43.50  ?  6838 ILE   B O      1 
ATOM   633  C  CB     . ILE   A  1 40  ? 96.465  -29.379 -4.246  1.00 45.10  ?  6838 ILE   B CB     1 
ATOM   634  C  CG1    . ILE   A  1 40  ? 96.871  -29.854 -5.646  1.00 43.40  ?  6838 ILE   B CG1    1 
ATOM   635  C  CG2    . ILE   A  1 40  ? 94.946  -29.139 -4.252  1.00 43.46  ?  6838 ILE   B CG2    1 
ATOM   636  C  CD1    . ILE   A  1 40  ? 96.555  -28.856 -6.738  1.00 43.31  ?  6838 ILE   B CD1    1 
ATOM   637  H  H      . ILE   A  1 40  ? 98.750  -29.199 -3.209  1.00 54.84  ?  6838 ILE   B H      1 
ATOM   638  H  HA     . ILE   A  1 40  ? 97.153  -27.453 -4.516  1.00 59.31  ?  6838 ILE   B HA     1 
ATOM   639  H  HB     . ILE   A  1 40  ? 96.698  -30.060 -3.595  1.00 54.64  ?  6838 ILE   B HB     1 
ATOM   640  H  HG12   . ILE   A  1 40  ? 97.828  -30.013 -5.657  1.00 52.60  ?  6838 ILE   B HG12   1 
ATOM   641  H  HG13   . ILE   A  1 40  ? 96.396  -30.675 -5.848  1.00 52.60  ?  6838 ILE   B HG13   1 
ATOM   642  H  HG21   . ILE   A  1 40  ? 94.523  -29.810 -4.811  1.00 52.68  ?  6838 ILE   B HG21   1 
ATOM   643  H  HG22   . ILE   A  1 40  ? 94.612  -29.206 -3.344  1.00 52.68  ?  6838 ILE   B HG22   1 
ATOM   644  H  HG23   . ILE   A  1 40  ? 94.768  -28.254 -4.606  1.00 52.68  ?  6838 ILE   B HG23   1 
ATOM   645  H  HD11   . ILE   A  1 40  ? 96.847  -29.217 -7.590  1.00 52.50  ?  6838 ILE   B HD11   1 
ATOM   646  H  HD12   . ILE   A  1 40  ? 95.598  -28.700 -6.756  1.00 52.50  ?  6838 ILE   B HD12   1 
ATOM   647  H  HD13   . ILE   A  1 40  ? 97.022  -28.027 -6.552  1.00 52.50  ?  6838 ILE   B HD13   1 
ATOM   648  N  N      . MET   A  1 41  ? 95.999  -26.343 -2.720  1.00 42.89  ?  6839 MET   B N      1 
ATOM   649  C  CA     . MET   A  1 41  ? 95.322  -25.605 -1.659  1.00 44.62  ?  6839 MET   B CA     1 
ATOM   650  C  C      . MET   A  1 41  ? 94.048  -26.325 -1.222  1.00 41.05  ?  6839 MET   B C      1 
ATOM   651  O  O      . MET   A  1 41  ? 93.323  -26.905 -2.038  1.00 42.36  ?  6839 MET   B O      1 
ATOM   652  C  CB     . MET   A  1 41  ? 94.899  -24.225 -2.186  1.00 54.33  ?  6839 MET   B CB     1 
ATOM   653  C  CG     . MET   A  1 41  ? 95.970  -23.162 -2.475  1.00 61.85  ?  6839 MET   B CG     1 
ATOM   654  S  SD     . MET   A  1 41  ? 95.245  -21.700 -3.309  1.00 55.43  ?  6839 MET   B SD     1 
ATOM   655  C  CE     . MET   A  1 41  ? 96.402  -20.393 -2.929  1.00 60.83  ?  6839 MET   B CE     1 
ATOM   656  H  H      . MET   A  1 41  ? 95.948  -25.941 -3.478  1.00 51.99  ?  6839 MET   B H      1 
ATOM   657  H  HA     . MET   A  1 41  ? 95.931  -25.513 -0.910  1.00 54.07  ?  6839 MET   B HA     1 
ATOM   658  H  HB2    . MET   A  1 41  ? 94.426  -24.366 -3.021  1.00 65.71  ?  6839 MET   B HB2    1 
ATOM   659  H  HB3    . MET   A  1 41  ? 94.302  -23.835 -1.528  1.00 65.71  ?  6839 MET   B HB3    1 
ATOM   660  H  HG2    . MET   A  1 41  ? 96.370  -22.872 -1.640  1.00 74.74  ?  6839 MET   B HG2    1 
ATOM   661  H  HG3    . MET   A  1 41  ? 96.650  -23.539 -3.055  1.00 74.74  ?  6839 MET   B HG3    1 
ATOM   662  H  HE1    . MET   A  1 41  ? 96.013  -19.542 -3.184  1.00 73.52  ?  6839 MET   B HE1    1 
ATOM   663  H  HE2    . MET   A  1 41  ? 96.586  -20.400 -1.977  1.00 73.52  ?  6839 MET   B HE2    1 
ATOM   664  H  HE3    . MET   A  1 41  ? 97.222  -20.543 -3.426  1.00 73.52  ?  6839 MET   B HE3    1 
ATOM   665  N  N      . MET   A  1 42  ? 93.738  -26.235 0.071   1.00 39.63  ?  6840 MET   B N      1 
ATOM   666  C  CA     . MET   A  1 42  ? 92.481  -26.789 0.572   1.00 40.53  ?  6840 MET   B CA     1 
ATOM   667  C  C      . MET   A  1 42  ? 91.266  -26.273 -0.190  1.00 39.27  ?  6840 MET   B C      1 
ATOM   668  O  O      . MET   A  1 42  ? 90.352  -27.045 -0.505  1.00 40.94  ?  6840 MET   B O      1 
ATOM   669  C  CB     . MET   A  1 42  ? 92.325  -26.497 2.065   1.00 39.04  ?  6840 MET   B CB     1 
ATOM   670  C  CG     . MET   A  1 42  ? 90.928  -26.806 2.616   1.00 39.25  ?  6840 MET   B CG     1 
ATOM   671  S  SD     . MET   A  1 42  ? 90.407  -28.520 2.451   1.00 49.08  ?  6840 MET   B SD     1 
ATOM   672  C  CE     . MET   A  1 42  ? 91.253  -29.248 3.843   1.00 49.17  ?  6840 MET   B CE     1 
ATOM   673  H  H      . MET   A  1 42  ? 94.230  -25.864 0.670   1.00 48.08  ?  6840 MET   B H      1 
ATOM   674  H  HA     . MET   A  1 42  ? 92.527  -27.751 0.454   1.00 49.15  ?  6840 MET   B HA     1 
ATOM   675  H  HB2    . MET   A  1 42  ? 92.962  -27.038 2.557   1.00 47.37  ?  6840 MET   B HB2    1 
ATOM   676  H  HB3    . MET   A  1 42  ? 92.501  -25.556 2.219   1.00 47.37  ?  6840 MET   B HB3    1 
ATOM   677  H  HG2    . MET   A  1 42  ? 90.916  -26.589 3.561   1.00 47.62  ?  6840 MET   B HG2    1 
ATOM   678  H  HG3    . MET   A  1 42  ? 90.283  -26.260 2.141   1.00 47.62  ?  6840 MET   B HG3    1 
ATOM   679  H  HE1    . MET   A  1 42  ? 91.088  -30.203 3.849   1.00 59.52  ?  6840 MET   B HE1    1 
ATOM   680  H  HE2    . MET   A  1 42  ? 92.205  -29.077 3.759   1.00 59.52  ?  6840 MET   B HE2    1 
ATOM   681  H  HE3    . MET   A  1 42  ? 90.917  -28.849 4.661   1.00 59.52  ?  6840 MET   B HE3    1 
ATOM   682  N  N      . ASN   A  1 43  ? 91.194  -24.967 -0.444  1.00 40.70  ?  6841 ASN   B N      1 
ATOM   683  C  CA     . ASN   A  1 43  ? 89.980  -24.464 -1.073  1.00 42.94  ?  6841 ASN   B CA     1 
ATOM   684  C  C      . ASN   A  1 43  ? 89.869  -24.875 -2.538  1.00 40.56  ?  6841 ASN   B C      1 
ATOM   685  O  O      . ASN   A  1 43  ? 88.753  -24.930 -3.065  1.00 42.30  ?  6841 ASN   B O      1 
ATOM   686  C  CB     . ASN   A  1 43  ? 89.871  -22.938 -0.919  1.00 47.51  ?  6841 ASN   B CB     1 
ATOM   687  C  CG     . ASN   A  1 43  ? 89.291  -22.518 0.451   1.00 59.59  ?  6841 ASN   B CG     1 
ATOM   688  O  OD1    . ASN   A  1 43  ? 89.458  -21.373 0.880   1.00 75.20  ?  6841 ASN   B OD1    1 
ATOM   689  N  ND2    . ASN   A  1 43  ? 88.634  -23.453 1.146   1.00 59.02  ?  6841 ASN   B ND2    1 
ATOM   690  H  H      . ASN   A  1 43  ? 91.803  -24.384 -0.271  1.00 49.37  ?  6841 ASN   B H      1 
ATOM   691  H  HA     . ASN   A  1 43  ? 89.217  -24.843 -0.609  1.00 52.05  ?  6841 ASN   B HA     1 
ATOM   692  H  HB2    . ASN   A  1 43  ? 90.754  -22.547 -1.004  1.00 57.53  ?  6841 ASN   B HB2    1 
ATOM   693  H  HB3    . ASN   A  1 43  ? 89.286  -22.591 -1.611  1.00 57.53  ?  6841 ASN   B HB3    1 
ATOM   694  H  HD21   . ASN   A  1 43  ? 88.550  -24.246 0.825   1.00 71.34  ?  6841 ASN   B HD21   1 
ATOM   695  H  HD22   . ASN   A  1 43  ? 88.297  -23.260 1.913   1.00 71.34  ?  6841 ASN   B HD22   1 
ATOM   696  N  N      . VAL   A  1 44  ? 90.981  -25.200 -3.200  1.00 41.82  ?  6842 VAL   B N      1 
ATOM   697  C  CA     . VAL   A  1 44  ? 90.901  -25.756 -4.550  1.00 38.84  ?  6842 VAL   B CA     1 
ATOM   698  C  C      . VAL   A  1 44  ? 90.328  -27.166 -4.502  1.00 36.04  ?  6842 VAL   B C      1 
ATOM   699  O  O      . VAL   A  1 44  ? 89.422  -27.515 -5.269  1.00 40.71  ?  6842 VAL   B O      1 
ATOM   700  C  CB     . VAL   A  1 44  ? 92.281  -25.737 -5.238  1.00 37.22  ?  6842 VAL   B CB     1 
ATOM   701  C  CG1    . VAL   A  1 44  ? 92.255  -26.589 -6.503  1.00 36.69  ?  6842 VAL   B CG1    1 
ATOM   702  C  CG2    . VAL   A  1 44  ? 92.671  -24.305 -5.571  1.00 42.44  ?  6842 VAL   B CG2    1 
ATOM   703  H  H      . VAL   A  1 44  ? 91.780  -25.109 -2.896  1.00 50.71  ?  6842 VAL   B H      1 
ATOM   704  H  HA     . VAL   A  1 44  ? 90.304  -25.198 -5.073  1.00 47.13  ?  6842 VAL   B HA     1 
ATOM   705  H  HB     . VAL   A  1 44  ? 92.945  -26.109 -4.637  1.00 45.18  ?  6842 VAL   B HB     1 
ATOM   706  H  HG11   . VAL   A  1 44  ? 93.017  -26.355 -7.057  1.00 44.55  ?  6842 VAL   B HG11   1 
ATOM   707  H  HG12   . VAL   A  1 44  ? 92.302  -27.525 -6.254  1.00 44.55  ?  6842 VAL   B HG12   1 
ATOM   708  H  HG13   . VAL   A  1 44  ? 91.431  -26.415 -6.984  1.00 44.55  ?  6842 VAL   B HG13   1 
ATOM   709  H  HG21   . VAL   A  1 44  ? 93.535  -24.308 -6.011  1.00 51.46  ?  6842 VAL   B HG21   1 
ATOM   710  H  HG22   . VAL   A  1 44  ? 92.001  -23.924 -6.160  1.00 51.46  ?  6842 VAL   B HG22   1 
ATOM   711  H  HG23   . VAL   A  1 44  ? 92.719  -23.792 -4.749  1.00 51.46  ?  6842 VAL   B HG23   1 
ATOM   712  N  N      . ALA   A  1 45  ? 90.835  -27.986 -3.575  1.00 42.48  ?  6843 ALA   B N      1 
ATOM   713  C  CA     . ALA   A  1 45  ? 90.353  -29.351 -3.426  1.00 38.63  ?  6843 ALA   B CA     1 
ATOM   714  C  C      . ALA   A  1 45  ? 88.884  -29.371 -3.028  1.00 40.13  ?  6843 ALA   B C      1 
ATOM   715  O  O      . ALA   A  1 45  ? 88.116  -30.224 -3.491  1.00 37.66  ?  6843 ALA   B O      1 
ATOM   716  C  CB     . ALA   A  1 45  ? 91.184  -30.101 -2.388  1.00 37.36  ?  6843 ALA   B CB     1 
ATOM   717  H  H      . ALA   A  1 45  ? 91.458  -27.772 -3.023  1.00 51.50  ?  6843 ALA   B H      1 
ATOM   718  H  HA     . ALA   A  1 45  ? 90.452  -29.805 -4.277  1.00 46.88  ?  6843 ALA   B HA     1 
ATOM   719  H  HB1    . ALA   A  1 45  ? 90.860  -31.013 -2.323  1.00 45.35  ?  6843 ALA   B HB1    1 
ATOM   720  H  HB2    . ALA   A  1 45  ? 92.113  -30.099 -2.667  1.00 45.35  ?  6843 ALA   B HB2    1 
ATOM   721  H  HB3    . ALA   A  1 45  ? 91.095  -29.657 -1.531  1.00 45.35  ?  6843 ALA   B HB3    1 
ATOM   722  N  N      . LYS   A  1 46  ? 88.479  -28.451 -2.151  1.00 42.88  ?  6844 LYS   B N      1 
ATOM   723  C  CA     . LYS   A  1 46  ? 87.109  -28.449 -1.654  1.00 39.31  ?  6844 LYS   B CA     1 
ATOM   724  C  C      . LYS   A  1 46  ? 86.134  -28.126 -2.784  1.00 36.98  ?  6844 LYS   B C      1 
ATOM   725  O  O      . LYS   A  1 46  ? 85.158  -28.855 -3.009  1.00 36.68  ?  6844 LYS   B O      1 
ATOM   726  C  CB     . LYS   A  1 46  ? 86.995  -27.462 -0.485  1.00 38.33  ?  6844 LYS   B CB     1 
ATOM   727  C  CG     . LYS   A  1 46  ? 85.600  -27.309 0.128   1.00 40.44  ?  6844 LYS   B CG     1 
ATOM   728  C  CD     . LYS   A  1 46  ? 85.518  -26.069 0.984   1.00 40.23  ?  6844 LYS   B CD     1 
ATOM   729  C  CE     . LYS   A  1 46  ? 86.407  -26.130 2.231   1.00 40.45  ?  6844 LYS   B CE     1 
ATOM   730  N  NZ     . LYS   A  1 46  ? 86.238  -24.918 3.108   1.00 47.23  ?  6844 LYS   B NZ     1 
ATOM   731  H  H      . LYS   A  1 46  ? 88.974  -27.824 -1.833  1.00 51.98  ?  6844 LYS   B H      1 
ATOM   732  H  HA     . LYS   A  1 46  ? 86.872  -29.326 -1.313  1.00 47.69  ?  6844 LYS   B HA     1 
ATOM   733  H  HB2    . LYS   A  1 46  ? 87.588  -27.760 0.223   1.00 46.51  ?  6844 LYS   B HB2    1 
ATOM   734  H  HB3    . LYS   A  1 46  ? 87.268  -26.586 -0.800  1.00 46.51  ?  6844 LYS   B HB3    1 
ATOM   735  H  HG2    . LYS   A  1 46  ? 84.942  -27.236 -0.581  1.00 49.05  ?  6844 LYS   B HG2    1 
ATOM   736  H  HG3    . LYS   A  1 46  ? 85.404  -28.079 0.684   1.00 49.05  ?  6844 LYS   B HG3    1 
ATOM   737  H  HD2    . LYS   A  1 46  ? 85.797  -25.305 0.457   1.00 48.79  ?  6844 LYS   B HD2    1 
ATOM   738  H  HD3    . LYS   A  1 46  ? 84.601  -25.952 1.279   1.00 48.79  ?  6844 LYS   B HD3    1 
ATOM   739  H  HE2    . LYS   A  1 46  ? 86.174  -26.915 2.751   1.00 49.06  ?  6844 LYS   B HE2    1 
ATOM   740  H  HE3    . LYS   A  1 46  ? 87.337  -26.178 1.957   1.00 49.06  ?  6844 LYS   B HE3    1 
ATOM   741  H  HZ1    . LYS   A  1 46  ? 86.442  -24.182 2.652   1.00 57.20  ?  6844 LYS   B HZ1    1 
ATOM   742  H  HZ2    . LYS   A  1 46  ? 85.395  -24.860 3.388   1.00 57.20  ?  6844 LYS   B HZ2    1 
ATOM   743  H  HZ3    . LYS   A  1 46  ? 86.774  -24.977 3.816   1.00 57.20  ?  6844 LYS   B HZ3    1 
ATOM   744  N  N      . TYR   A  1 47  ? 86.397  -27.050 -3.526  1.00 38.82  ?  6845 TYR   B N      1 
ATOM   745  C  CA     . TYR   A  1 47  ? 85.531  -26.691 -4.645  1.00 43.02  ?  6845 TYR   B CA     1 
ATOM   746  C  C      . TYR   A  1 47  ? 85.551  -27.750 -5.735  1.00 38.70  ?  6845 TYR   B C      1 
ATOM   747  O  O      . TYR   A  1 47  ? 84.540  -27.940 -6.421  1.00 42.92  ?  6845 TYR   B O      1 
ATOM   748  C  CB     . TYR   A  1 47  ? 85.958  -25.350 -5.240  1.00 36.45  ?  6845 TYR   B CB     1 
ATOM   749  C  CG     . TYR   A  1 47  ? 85.357  -24.131 -4.575  1.00 37.61  ?  6845 TYR   B CG     1 
ATOM   750  C  CD1    . TYR   A  1 47  ? 85.758  -23.729 -3.299  1.00 38.92  ?  6845 TYR   B CD1    1 
ATOM   751  C  CD2    . TYR   A  1 47  ? 84.393  -23.367 -5.228  1.00 40.22  ?  6845 TYR   B CD2    1 
ATOM   752  C  CE1    . TYR   A  1 47  ? 85.221  -22.601 -2.704  1.00 45.28  ?  6845 TYR   B CE1    1 
ATOM   753  C  CE2    . TYR   A  1 47  ? 83.850  -22.247 -4.637  1.00 41.89  ?  6845 TYR   B CE2    1 
ATOM   754  C  CZ     . TYR   A  1 47  ? 84.266  -21.873 -3.376  1.00 39.91  ?  6845 TYR   B CZ     1 
ATOM   755  O  OH     . TYR   A  1 47  ? 83.722  -20.763 -2.781  1.00 43.55  ?  6845 TYR   B OH     1 
ATOM   756  H  H      . TYR   A  1 47  ? 87.061  -26.518 -3.404  1.00 47.11  ?  6845 TYR   B H      1 
ATOM   757  H  HA     . TYR   A  1 47  ? 84.625  -26.606 -4.308  1.00 52.15  ?  6845 TYR   B HA     1 
ATOM   758  H  HB2    . TYR   A  1 47  ? 86.923  -25.276 -5.166  1.00 44.26  ?  6845 TYR   B HB2    1 
ATOM   759  H  HB3    . TYR   A  1 47  ? 85.695  -25.331 -6.173  1.00 44.26  ?  6845 TYR   B HB3    1 
ATOM   760  H  HD1    . TYR   A  1 47  ? 86.396  -24.228 -2.841  1.00 47.22  ?  6845 TYR   B HD1    1 
ATOM   761  H  HD2    . TYR   A  1 47  ? 84.111  -23.618 -6.077  1.00 48.79  ?  6845 TYR   B HD2    1 
ATOM   762  H  HE1    . TYR   A  1 47  ? 85.503  -22.337 -1.858  1.00 54.86  ?  6845 TYR   B HE1    1 
ATOM   763  H  HE2    . TYR   A  1 47  ? 83.207  -21.746 -5.085  1.00 50.79  ?  6845 TYR   B HE2    1 
ATOM   764  H  HH     . TYR   A  1 47  ? 84.104  -20.614 -2.048  1.00 52.79  ?  6845 TYR   B HH     1 
ATOM   765  N  N      . THR   A  1 48  ? 86.684  -28.423 -5.946  1.00 43.67  ?  6846 THR   B N      1 
ATOM   766  C  CA     . THR   A  1 48  ? 86.713  -29.475 -6.956  1.00 45.06  ?  6846 THR   B CA     1 
ATOM   767  C  C      . THR   A  1 48  ? 85.751  -30.596 -6.589  1.00 40.14  ?  6846 THR   B C      1 
ATOM   768  O  O      . THR   A  1 48  ? 84.975  -31.070 -7.426  1.00 39.14  ?  6846 THR   B O      1 
ATOM   769  C  CB     . THR   A  1 48  ? 88.139  -30.023 -7.108  1.00 40.34  ?  6846 THR   B CB     1 
ATOM   770  O  OG1    . THR   A  1 48  ? 89.028  -28.960 -7.449  1.00 44.92  ?  6846 THR   B OG1    1 
ATOM   771  C  CG2    . THR   A  1 48  ? 88.205  -31.085 -8.185  1.00 41.54  ?  6846 THR   B CG2    1 
ATOM   772  H  H      . THR   A  1 48  ? 87.425  -28.293 -5.529  1.00 52.92  ?  6846 THR   B H      1 
ATOM   773  H  HA     . THR   A  1 48  ? 86.442  -29.101 -7.809  1.00 54.59  ?  6846 THR   B HA     1 
ATOM   774  H  HB     . THR   A  1 48  ? 88.412  -30.425 -6.269  1.00 48.93  ?  6846 THR   B HB     1 
ATOM   775  H  HG1    . THR   A  1 48  ? 89.051  -28.394 -6.828  1.00 54.42  ?  6846 THR   B HG1    1 
ATOM   776  H  HG21   . THR   A  1 48  ? 89.125  -31.355 -8.328  1.00 50.36  ?  6846 THR   B HG21   1 
ATOM   777  H  HG22   . THR   A  1 48  ? 87.687  -31.860 -7.919  1.00 50.36  ?  6846 THR   B HG22   1 
ATOM   778  H  HG23   . THR   A  1 48  ? 87.846  -30.737 -9.016  1.00 50.36  ?  6846 THR   B HG23   1 
ATOM   779  N  N      . GLN   A  1 49  ? 85.774  -31.017 -5.325  1.00 39.32  ?  6847 GLN   B N      1 
ATOM   780  C  CA     . GLN   A  1 49  ? 84.889  -32.091 -4.900  1.00 38.76  ?  6847 GLN   B CA     1 
ATOM   781  C  C      . GLN   A  1 49  ? 83.437  -31.654 -4.968  1.00 36.12  ?  6847 GLN   B C      1 
ATOM   782  O  O      . GLN   A  1 49  ? 82.568  -32.414 -5.410  1.00 39.79  ?  6847 GLN   B O      1 
ATOM   783  C  CB     . GLN   A  1 49  ? 85.263  -32.555 -3.497  1.00 39.62  ?  6847 GLN   B CB     1 
ATOM   784  C  CG     . GLN   A  1 49  ? 86.431  -33.474 -3.615  1.00 36.55  ?  6847 GLN   B CG     1 
ATOM   785  C  CD     . GLN   A  1 49  ? 86.867  -34.125 -2.333  1.00 35.68  ?  6847 GLN   B CD     1 
ATOM   786  O  OE1    . GLN   A  1 49  ? 86.586  -33.634 -1.264  1.00 40.15  ?  6847 GLN   B OE1    1 
ATOM   787  N  NE2    . GLN   A  1 49  ? 87.582  -35.232 -2.443  1.00 41.52  ?  6847 GLN   B NE2    1 
ATOM   788  H  H      . GLN   A  1 49  ? 86.284  -30.702 -4.708  1.00 47.71  ?  6847 GLN   B H      1 
ATOM   789  H  HA     . GLN   A  1 49  ? 84.998  -32.850 -5.494  1.00 47.04  ?  6847 GLN   B HA     1 
ATOM   790  H  HB2    . GLN   A  1 49  ? 85.508  -31.794 -2.948  1.00 48.07  ?  6847 GLN   B HB2    1 
ATOM   791  H  HB3    . GLN   A  1 49  ? 84.521  -33.030 -3.093  1.00 48.07  ?  6847 GLN   B HB3    1 
ATOM   792  H  HG2    . GLN   A  1 49  ? 86.201  -34.183 -4.236  1.00 44.38  ?  6847 GLN   B HG2    1 
ATOM   793  H  HG3    . GLN   A  1 49  ? 87.186  -32.968 -3.953  1.00 44.38  ?  6847 GLN   B HG3    1 
ATOM   794  H  HE21   . GLN   A  1 49  ? 87.775  -35.543 -3.222  1.00 50.35  ?  6847 GLN   B HE21   1 
ATOM   795  H  HE22   . GLN   A  1 49  ? 87.854  -35.640 -1.737  1.00 50.35  ?  6847 GLN   B HE22   1 
ATOM   796  N  N      . LEU   A  1 50  ? 83.161  -30.420 -4.536  1.00 41.61  ?  6848 LEU   B N      1 
ATOM   797  C  CA     . LEU   A  1 50  ? 81.829  -29.848 -4.686  1.00 40.87  ?  6848 LEU   B CA     1 
ATOM   798  C  C      . LEU   A  1 50  ? 81.343  -29.951 -6.125  1.00 39.94  ?  6848 LEU   B C      1 
ATOM   799  O  O      . LEU   A  1 50  ? 80.222  -30.405 -6.381  1.00 38.01  ?  6848 LEU   B O      1 
ATOM   800  C  CB     . LEU   A  1 50  ? 81.832  -28.393 -4.216  1.00 40.66  ?  6848 LEU   B CB     1 
ATOM   801  C  CG     . LEU   A  1 50  ? 80.542  -27.632 -4.518  1.00 39.31  ?  6848 LEU   B CG     1 
ATOM   802  C  CD1    . LEU   A  1 50  ? 79.404  -28.433 -3.883  1.00 42.79  ?  6848 LEU   B CD1    1 
ATOM   803  C  CD2    . LEU   A  1 50  ? 80.547  -26.235 -4.017  1.00 37.15  ?  6848 LEU   B CD2    1 
ATOM   804  H  H      . LEU   A  1 50  ? 83.728  -29.899 -4.154  1.00 50.45  ?  6848 LEU   B H      1 
ATOM   805  H  HA     . LEU   A  1 50  ? 81.210  -30.342 -4.126  1.00 49.57  ?  6848 LEU   B HA     1 
ATOM   806  H  HB2    . LEU   A  1 50  ? 81.965  -28.378 -3.255  1.00 49.32  ?  6848 LEU   B HB2    1 
ATOM   807  H  HB3    . LEU   A  1 50  ? 82.559  -27.927 -4.658  1.00 49.32  ?  6848 LEU   B HB3    1 
ATOM   808  H  HG     . LEU   A  1 50  ? 80.429  -27.546 -5.478  1.00 47.69  ?  6848 LEU   B HG     1 
ATOM   809  H  HD11   . LEU   A  1 50  ? 78.630  -27.857 -3.782  1.00 51.87  ?  6848 LEU   B HD11   1 
ATOM   810  H  HD12   . LEU   A  1 50  ? 79.186  -29.182 -4.458  1.00 51.87  ?  6848 LEU   B HD12   1 
ATOM   811  H  HD13   . LEU   A  1 50  ? 79.691  -28.755 -3.014  1.00 51.87  ?  6848 LEU   B HD13   1 
ATOM   812  H  HD21   . LEU   A  1 50  ? 79.718  -25.803 -4.276  1.00 45.10  ?  6848 LEU   B HD21   1 
ATOM   813  H  HD22   . LEU   A  1 50  ? 80.626  -26.247 -3.050  1.00 45.10  ?  6848 LEU   B HD22   1 
ATOM   814  H  HD23   . LEU   A  1 50  ? 81.301  -25.763 -4.404  1.00 45.10  ?  6848 LEU   B HD23   1 
ATOM   815  N  N      . CYS   A  1 51  ? 82.166  -29.507 -7.078  1.00 41.77  ?  6849 CYS   B N      1 
ATOM   816  C  CA     . CYS   A  1 51  ? 81.741  -29.533 -8.477  1.00 42.48  ?  6849 CYS   B CA     1 
ATOM   817  C  C      . CYS   A  1 51  ? 81.624  -30.966 -8.986  1.00 36.42  ?  6849 CYS   B C      1 
ATOM   818  O  O      . CYS   A  1 51  ? 80.751  -31.266 -9.803  1.00 37.90  ?  6849 CYS   B O      1 
ATOM   819  C  CB     . CYS   A  1 51  ? 82.736  -28.741 -9.335  1.00 38.54  ?  6849 CYS   B CB     1 
ATOM   820  S  SG     . CYS   A  1 51  ? 82.746  -26.959 -9.086  1.00 40.58  ?  6849 CYS   B SG     1 
ATOM   821  H  H      . CYS   A  1 51  ? 82.955  -29.193 -6.945  1.00 50.64  ?  6849 CYS   B H      1 
ATOM   822  H  HA     . CYS   A  1 51  ? 80.871  -29.112 -8.552  1.00 51.50  ?  6849 CYS   B HA     1 
ATOM   823  H  HB2    . CYS   A  1 51  ? 83.629  -29.063 -9.139  1.00 46.77  ?  6849 CYS   B HB2    1 
ATOM   824  H  HB3    . CYS   A  1 51  ? 82.523  -28.898 -10.268 1.00 46.77  ?  6849 CYS   B HB3    1 
ATOM   825  H  HG     . CYS   A  1 51  ? 83.511  -26.460 -9.864  1.00 49.22  ?  6849 CYS   B HG     1 
ATOM   826  N  N      . GLN   A  1 52  ? 82.523  -31.851 -8.548  1.00 41.46  ?  6850 GLN   B N      1 
ATOM   827  C  CA     . GLN   A  1 52  ? 82.382  -33.276 -8.859  1.00 43.77  ?  6850 GLN   B CA     1 
ATOM   828  C  C      . GLN   A  1 52  ? 81.038  -33.816 -8.397  1.00 40.52  ?  6850 GLN   B C      1 
ATOM   829  O  O      . GLN   A  1 52  ? 80.400  -34.603 -9.107  1.00 41.22  ?  6850 GLN   B O      1 
ATOM   830  C  CB     . GLN   A  1 52  ? 83.521  -34.075 -8.226  1.00 41.24  ?  6850 GLN   B CB     1 
ATOM   831  C  CG     . GLN   A  1 52  ? 84.825  -33.986 -8.949  1.00 41.75  ?  6850 GLN   B CG     1 
ATOM   832  C  CD     . GLN   A  1 52  ? 85.941  -34.664 -8.201  1.00 42.12  ?  6850 GLN   B CD     1 
ATOM   833  O  OE1    . GLN   A  1 52  ? 85.928  -34.716 -6.974  1.00 42.17  ?  6850 GLN   B OE1    1 
ATOM   834  N  NE2    . GLN   A  1 52  ? 86.894  -35.222 -8.932  1.00 40.76  ?  6850 GLN   B NE2    1 
ATOM   835  H  H      . GLN   A  1 52  ? 83.215  -31.656 -8.077  1.00 50.28  ?  6850 GLN   B H      1 
ATOM   836  H  HA     . GLN   A  1 52  ? 82.437  -33.386 -9.822  1.00 53.05  ?  6850 GLN   B HA     1 
ATOM   837  H  HB2    . GLN   A  1 52  ? 83.663  -33.745 -7.325  1.00 50.01  ?  6850 GLN   B HB2    1 
ATOM   838  H  HB3    . GLN   A  1 52  ? 83.264  -35.010 -8.201  1.00 50.01  ?  6850 GLN   B HB3    1 
ATOM   839  H  HG2    . GLN   A  1 52  ? 84.739  -34.414 -9.815  1.00 50.62  ?  6850 GLN   B HG2    1 
ATOM   840  H  HG3    . GLN   A  1 52  ? 85.062  -33.052 -9.063  1.00 50.62  ?  6850 GLN   B HG3    1 
ATOM   841  H  HE21   . GLN   A  1 52  ? 86.855  -35.186 -9.790  1.00 49.43  ?  6850 GLN   B HE21   1 
ATOM   842  H  HE22   . GLN   A  1 52  ? 87.552  -35.622 -8.548  1.00 49.43  ?  6850 GLN   B HE22   1 
ATOM   843  N  N      . TYR   A  1 53  ? 80.601  -33.428 -7.198  1.00 39.28  ?  6851 TYR   B N      1 
ATOM   844  C  CA     . TYR   A  1 53  ? 79.279  -33.834 -6.744  1.00 39.33  ?  6851 TYR   B CA     1 
ATOM   845  C  C      . TYR   A  1 53  ? 78.182  -33.189 -7.579  1.00 40.03  ?  6851 TYR   B C      1 
ATOM   846  O  O      . TYR   A  1 53  ? 77.168  -33.828 -7.888  1.00 37.63  ?  6851 TYR   B O      1 
ATOM   847  C  CB     . TYR   A  1 53  ? 79.080  -33.470 -5.280  1.00 40.29  ?  6851 TYR   B CB     1 
ATOM   848  C  CG     . TYR   A  1 53  ? 77.730  -33.913 -4.803  1.00 37.55  ?  6851 TYR   B CG     1 
ATOM   849  C  CD1    . TYR   A  1 53  ? 77.451  -35.262 -4.621  1.00 39.13  ?  6851 TYR   B CD1    1 
ATOM   850  C  CD2    . TYR   A  1 53  ? 76.722  -32.990 -4.551  1.00 39.52  ?  6851 TYR   B CD2    1 
ATOM   851  C  CE1    . TYR   A  1 53  ? 76.189  -35.683 -4.181  1.00 38.87  ?  6851 TYR   B CE1    1 
ATOM   852  C  CE2    . TYR   A  1 53  ? 75.470  -33.398 -4.118  1.00 38.13  ?  6851 TYR   B CE2    1 
ATOM   853  C  CZ     . TYR   A  1 53  ? 75.213  -34.742 -3.939  1.00 37.06  ?  6851 TYR   B CZ     1 
ATOM   854  O  OH     . TYR   A  1 53  ? 73.983  -35.156 -3.499  1.00 45.16  ?  6851 TYR   B OH     1 
ATOM   855  H  H      . TYR   A  1 53  ? 81.043  -32.942 -6.643  1.00 47.66  ?  6851 TYR   B H      1 
ATOM   856  H  HA     . TYR   A  1 53  ? 79.216  -34.797 -6.833  1.00 47.72  ?  6851 TYR   B HA     1 
ATOM   857  H  HB2    . TYR   A  1 53  ? 79.757  -33.910 -4.743  1.00 48.88  ?  6851 TYR   B HB2    1 
ATOM   858  H  HB3    . TYR   A  1 53  ? 79.145  -32.508 -5.174  1.00 48.88  ?  6851 TYR   B HB3    1 
ATOM   859  H  HD1    . TYR   A  1 53  ? 78.111  -35.894 -4.793  1.00 47.48  ?  6851 TYR   B HD1    1 
ATOM   860  H  HD2    . TYR   A  1 53  ? 76.890  -32.084 -4.675  1.00 47.94  ?  6851 TYR   B HD2    1 
ATOM   861  H  HE1    . TYR   A  1 53  ? 76.013  -36.587 -4.053  1.00 47.16  ?  6851 TYR   B HE1    1 
ATOM   862  H  HE2    . TYR   A  1 53  ? 74.807  -32.769 -3.949  1.00 46.28  ?  6851 TYR   B HE2    1 
ATOM   863  H  HH     . TYR   A  1 53  ? 73.958  -35.995 -3.465  1.00 54.71  ?  6851 TYR   B HH     1 
ATOM   864  N  N      . LEU   A  1 54  ? 78.362  -31.919 -7.947  1.00 40.43  ?  6852 LEU   B N      1 
ATOM   865  C  CA     . LEU   A  1 54  ? 77.339  -31.239 -8.725  1.00 41.12  ?  6852 LEU   B CA     1 
ATOM   866  C  C      . LEU   A  1 54  ? 77.161  -31.895 -10.084 1.00 40.97  ?  6852 LEU   B C      1 
ATOM   867  O  O      . LEU   A  1 54  ? 76.056  -31.867 -10.639 1.00 40.06  ?  6852 LEU   B O      1 
ATOM   868  C  CB     . LEU   A  1 54  ? 77.690  -29.755 -8.868  1.00 43.66  ?  6852 LEU   B CB     1 
ATOM   869  C  CG     . LEU   A  1 54  ? 77.557  -29.013 -7.541  1.00 39.83  ?  6852 LEU   B CG     1 
ATOM   870  C  CD1    . LEU   A  1 54  ? 78.038  -27.574 -7.733  1.00 41.66  ?  6852 LEU   B CD1    1 
ATOM   871  C  CD2    . LEU   A  1 54  ? 76.137  -29.005 -7.038  1.00 39.51  ?  6852 LEU   B CD2    1 
ATOM   872  H  H      . LEU   A  1 54  ? 79.053  -31.442 -7.762  1.00 49.04  ?  6852 LEU   B H      1 
ATOM   873  H  HA     . LEU   A  1 54  ? 76.490  -31.291 -8.259  1.00 49.86  ?  6852 LEU   B HA     1 
ATOM   874  H  HB2    . LEU   A  1 54  ? 78.607  -29.672 -9.174  1.00 52.91  ?  6852 LEU   B HB2    1 
ATOM   875  H  HB3    . LEU   A  1 54  ? 77.088  -29.345 -9.509  1.00 52.91  ?  6852 LEU   B HB3    1 
ATOM   876  H  HG     . LEU   A  1 54  ? 78.096  -29.466 -6.874  1.00 48.32  ?  6852 LEU   B HG     1 
ATOM   877  H  HD11   . LEU   A  1 54  ? 77.969  -27.103 -6.888  1.00 50.52  ?  6852 LEU   B HD11   1 
ATOM   878  H  HD12   . LEU   A  1 54  ? 78.962  -27.586 -8.030  1.00 50.52  ?  6852 LEU   B HD12   1 
ATOM   879  H  HD13   . LEU   A  1 54  ? 77.482  -27.141 -8.399  1.00 50.52  ?  6852 LEU   B HD13   1 
ATOM   880  H  HD21   . LEU   A  1 54  ? 76.054  -28.338 -6.339  1.00 47.94  ?  6852 LEU   B HD21   1 
ATOM   881  H  HD22   . LEU   A  1 54  ? 75.543  -28.788 -7.774  1.00 47.94  ?  6852 LEU   B HD22   1 
ATOM   882  H  HD23   . LEU   A  1 54  ? 75.922  -29.882 -6.686  1.00 47.94  ?  6852 LEU   B HD23   1 
ATOM   883  N  N      . ASN   A  1 55  ? 78.215  -32.536 -10.609 1.00 39.20  ?  6853 ASN   B N      1 
ATOM   884  C  CA     . ASN   A  1 55  ? 78.089  -33.148 -11.922 1.00 41.33  ?  6853 ASN   B CA     1 
ATOM   885  C  C      . ASN   A  1 55  ? 77.104  -34.311 -11.883 1.00 42.45  ?  6853 ASN   B C      1 
ATOM   886  O  O      . ASN   A  1 55  ? 76.651  -34.763 -12.941 1.00 44.53  ?  6853 ASN   B O      1 
ATOM   887  C  CB     . ASN   A  1 55  ? 79.417  -33.682 -12.478 1.00 43.53  ?  6853 ASN   B CB     1 
ATOM   888  C  CG     . ASN   A  1 55  ? 80.313  -32.572 -12.977 1.00 35.52  ?  6853 ASN   B CG     1 
ATOM   889  O  OD1    . ASN   A  1 55  ? 79.829  -31.547 -13.437 1.00 44.47  ?  6853 ASN   B OD1    1 
ATOM   890  N  ND2    . ASN   A  1 55  ? 81.607  -32.819 -12.989 1.00 43.92  ?  6853 ASN   B ND2    1 
ATOM   891  H  H      . ASN   A  1 55  ? 78.984  -32.623 -10.232 1.00 47.57  ?  6853 ASN   B H      1 
ATOM   892  H  HA     . ASN   A  1 55  ? 77.795  -32.448 -12.527 1.00 50.12  ?  6853 ASN   B HA     1 
ATOM   893  H  HB2    . ASN   A  1 55  ? 79.887  -34.159 -11.776 1.00 52.75  ?  6853 ASN   B HB2    1 
ATOM   894  H  HB3    . ASN   A  1 55  ? 79.234  -34.280 -13.220 1.00 52.75  ?  6853 ASN   B HB3    1 
ATOM   895  H  HD21   . ASN   A  1 55  ? 81.902  -33.582 -12.722 1.00 53.23  ?  6853 ASN   B HD21   1 
ATOM   896  H  HD22   . ASN   A  1 55  ? 82.157  -32.218 -13.264 1.00 53.23  ?  6853 ASN   B HD22   1 
ATOM   897  N  N      . THR   A  1 56  ? 76.796  -34.833 -10.694 1.00 44.78  ?  6854 THR   B N      1 
ATOM   898  C  CA     . THR   A  1 56  ? 75.881  -35.958 -10.575 1.00 38.93  ?  6854 THR   B CA     1 
ATOM   899  C  C      . THR   A  1 56  ? 74.427  -35.531 -10.460 1.00 38.85  ?  6854 THR   B C      1 
ATOM   900  O  O      . THR   A  1 56  ? 73.544  -36.399 -10.429 1.00 48.81  ?  6854 THR   B O      1 
ATOM   901  C  CB     . THR   A  1 56  ? 76.215  -36.824 -9.357  1.00 40.22  ?  6854 THR   B CB     1 
ATOM   902  O  OG1    . THR   A  1 56  ? 75.862  -36.130 -8.154  1.00 44.38  ?  6854 THR   B OG1    1 
ATOM   903  C  CG2    . THR   A  1 56  ? 77.701  -37.171 -9.328  1.00 41.33  ?  6854 THR   B CG2    1 
ATOM   904  H  H      . THR   A  1 56  ? 77.107  -34.550 -9.944  1.00 54.26  ?  6854 THR   B H      1 
ATOM   905  H  HA     . THR   A  1 56  ? 75.991  -36.503 -11.370 1.00 47.24  ?  6854 THR   B HA     1 
ATOM   906  H  HB     . THR   A  1 56  ? 75.712  -37.652 -9.408  1.00 48.79  ?  6854 THR   B HB     1 
ATOM   907  H  HG1    . THR   A  1 56  ? 76.340  -35.444 -8.067  1.00 53.78  ?  6854 THR   B HG1    1 
ATOM   908  H  HG21   . THR   A  1 56  ? 77.873  -37.836 -8.643  1.00 50.12  ?  6854 THR   B HG21   1 
ATOM   909  H  HG22   . THR   A  1 56  ? 77.975  -37.526 -10.188 1.00 50.12  ?  6854 THR   B HG22   1 
ATOM   910  H  HG23   . THR   A  1 56  ? 78.223  -36.377 -9.134  1.00 50.12  ?  6854 THR   B HG23   1 
ATOM   911  N  N      . LEU   A  1 57  ? 74.151  -34.238 -10.396 1.00 42.31  ?  6855 LEU   B N      1 
ATOM   912  C  CA     . LEU   A  1 57  ? 72.786  -33.755 -10.274 1.00 38.38  ?  6855 LEU   B CA     1 
ATOM   913  C  C      . LEU   A  1 57  ? 72.293  -33.233 -11.613 1.00 37.56  ?  6855 LEU   B C      1 
ATOM   914  O  O      . LEU   A  1 57  ? 73.038  -33.149 -12.589 1.00 51.10  ?  6855 LEU   B O      1 
ATOM   915  C  CB     . LEU   A  1 57  ? 72.688  -32.658 -9.216  1.00 40.05  ?  6855 LEU   B CB     1 
ATOM   916  C  CG     . LEU   A  1 57  ? 73.344  -32.908 -7.868  1.00 42.38  ?  6855 LEU   B CG     1 
ATOM   917  C  CD1    . LEU   A  1 57  ? 73.104  -31.707 -6.955  1.00 44.40  ?  6855 LEU   B CD1    1 
ATOM   918  C  CD2    . LEU   A  1 57  ? 72.776  -34.173 -7.230  1.00 40.77  ?  6855 LEU   B CD2    1 
ATOM   919  H  H      . LEU   A  1 57  ? 74.744  -33.615 -10.421 1.00 51.29  ?  6855 LEU   B H      1 
ATOM   920  H  HA     . LEU   A  1 57  ? 72.229  -34.500 -9.999  1.00 46.58  ?  6855 LEU   B HA     1 
ATOM   921  H  HB2    . LEU   A  1 57  ? 73.098  -31.859 -9.582  1.00 48.58  ?  6855 LEU   B HB2    1 
ATOM   922  H  HB3    . LEU   A  1 57  ? 71.747  -32.500 -9.043  1.00 48.58  ?  6855 LEU   B HB3    1 
ATOM   923  H  HG     . LEU   A  1 57  ? 74.299  -33.030 -7.986  1.00 51.38  ?  6855 LEU   B HG     1 
ATOM   924  H  HD11   . LEU   A  1 57  ? 73.535  -31.867 -6.102  1.00 53.80  ?  6855 LEU   B HD11   1 
ATOM   925  H  HD12   . LEU   A  1 57  ? 73.477  -30.914 -7.371  1.00 53.80  ?  6855 LEU   B HD12   1 
ATOM   926  H  HD13   . LEU   A  1 57  ? 72.149  -31.594 -6.827  1.00 53.80  ?  6855 LEU   B HD13   1 
ATOM   927  H  HD21   . LEU   A  1 57  ? 73.194  -34.305 -6.365  1.00 49.45  ?  6855 LEU   B HD21   1 
ATOM   928  H  HD22   . LEU   A  1 57  ? 71.818  -34.070 -7.123  1.00 49.45  ?  6855 LEU   B HD22   1 
ATOM   929  H  HD23   . LEU   A  1 57  ? 72.965  -34.930 -7.807  1.00 49.45  ?  6855 LEU   B HD23   1 
ATOM   930  N  N      . THR   A  1 58  ? 71.023  -32.835 -11.641 1.00 52.42  ?  6856 THR   B N      1 
ATOM   931  C  CA     . THR   A  1 58  ? 70.361  -32.414 -12.879 1.00 48.98  ?  6856 THR   B CA     1 
ATOM   932  C  C      . THR   A  1 58  ? 70.411  -30.896 -13.034 1.00 39.09  ?  6856 THR   B C      1 
ATOM   933  O  O      . THR   A  1 58  ? 69.396  -30.209 -13.137 1.00 42.84  ?  6856 THR   B O      1 
ATOM   934  C  CB     . THR   A  1 58  ? 68.923  -32.905 -12.897 1.00 46.65  ?  6856 THR   B CB     1 
ATOM   935  O  OG1    . THR   A  1 58  ? 68.281  -32.522 -11.673 1.00 45.86  ?  6856 THR   B OG1    1 
ATOM   936  C  CG2    . THR   A  1 58  ? 68.886  -34.421 -13.032 1.00 48.52  ?  6856 THR   B CG2    1 
ATOM   937  H  H      . THR   A  1 58  ? 70.515  -32.799 -10.948 1.00 63.43  ?  6856 THR   B H      1 
ATOM   938  H  HA     . THR   A  1 58  ? 70.836  -32.812 -13.625 1.00 59.29  ?  6856 THR   B HA     1 
ATOM   939  H  HB     . THR   A  1 58  ? 68.449  -32.518 -13.649 1.00 56.50  ?  6856 THR   B HB     1 
ATOM   940  H  HG1    . THR   A  1 58  ? 68.285  -31.685 -11.596 1.00 55.55  ?  6856 THR   B HG1    1 
ATOM   941  H  HG21   . THR   A  1 58  ? 67.967  -34.727 -13.081 1.00 58.75  ?  6856 THR   B HG21   1 
ATOM   942  H  HG22   . THR   A  1 58  ? 69.352  -34.693 -13.839 1.00 58.75  ?  6856 THR   B HG22   1 
ATOM   943  H  HG23   . THR   A  1 58  ? 69.316  -34.833 -12.266 1.00 58.75  ?  6856 THR   B HG23   1 
ATOM   944  N  N      . LEU   A  1 59  ? 71.629  -30.373 -13.068 1.00 40.75  ?  6857 LEU   B N      1 
ATOM   945  C  CA     . LEU   A  1 59  ? 71.792  -28.941 -13.279 1.00 42.24  ?  6857 LEU   B CA     1 
ATOM   946  C  C      . LEU   A  1 59  ? 71.365  -28.550 -14.685 1.00 41.79  ?  6857 LEU   B C      1 
ATOM   947  O  O      . LEU   A  1 59  ? 71.691  -29.231 -15.664 1.00 46.52  ?  6857 LEU   B O      1 
ATOM   948  C  CB     . LEU   A  1 59  ? 73.237  -28.520 -13.053 1.00 43.94  ?  6857 LEU   B CB     1 
ATOM   949  C  CG     . LEU   A  1 59  ? 73.827  -28.742 -11.665 1.00 46.20  ?  6857 LEU   B CG     1 
ATOM   950  C  CD1    . LEU   A  1 59  ? 75.095  -27.950 -11.498 1.00 46.30  ?  6857 LEU   B CD1    1 
ATOM   951  C  CD2    . LEU   A  1 59  ? 72.803  -28.326 -10.613 1.00 45.39  ?  6857 LEU   B CD2    1 
ATOM   952  H  H      . LEU   A  1 59  ? 72.361  -30.814 -12.974 1.00 49.42  ?  6857 LEU   B H      1 
ATOM   953  H  HA     . LEU   A  1 59  ? 71.234  -28.470 -12.641 1.00 51.21  ?  6857 LEU   B HA     1 
ATOM   954  H  HB2    . LEU   A  1 59  ? 73.791  -29.016 -13.676 1.00 53.25  ?  6857 LEU   B HB2    1 
ATOM   955  H  HB3    . LEU   A  1 59  ? 73.301  -27.569 -13.236 1.00 53.25  ?  6857 LEU   B HB3    1 
ATOM   956  H  HG     . LEU   A  1 59  ? 74.044  -29.680 -11.546 1.00 55.96  ?  6857 LEU   B HG     1 
ATOM   957  H  HD11   . LEU   A  1 59  ? 75.479  -28.147 -10.629 1.00 56.08  ?  6857 LEU   B HD11   1 
ATOM   958  H  HD12   . LEU   A  1 59  ? 75.718  -28.200 -12.199 1.00 56.08  ?  6857 LEU   B HD12   1 
ATOM   959  H  HD13   . LEU   A  1 59  ? 74.888  -27.004 -11.562 1.00 56.08  ?  6857 LEU   B HD13   1 
ATOM   960  H  HD21   . LEU   A  1 59  ? 73.243  -28.264 -9.751  1.00 55.00  ?  6857 LEU   B HD21   1 
ATOM   961  H  HD22   . LEU   A  1 59  ? 72.431  -27.464 -10.858 1.00 55.00  ?  6857 LEU   B HD22   1 
ATOM   962  H  HD23   . LEU   A  1 59  ? 72.098  -28.992 -10.578 1.00 55.00  ?  6857 LEU   B HD23   1 
ATOM   963  N  N      . ALA   A  1 60  ? 70.632  -27.444 -14.775 1.00 42.95  ?  6858 ALA   B N      1 
ATOM   964  C  CA     . ALA   A  1 60  ? 70.431  -26.775 -16.051 1.00 42.65  ?  6858 ALA   B CA     1 
ATOM   965  C  C      . ALA   A  1 60  ? 71.732  -26.086 -16.458 1.00 45.04  ?  6858 ALA   B C      1 
ATOM   966  O  O      . ALA   A  1 60  ? 72.352  -25.380 -15.655 1.00 40.72  ?  6858 ALA   B O      1 
ATOM   967  C  CB     . ALA   A  1 60  ? 69.286  -25.765 -15.936 1.00 42.99  ?  6858 ALA   B CB     1 
ATOM   968  H  H      . ALA   A  1 60  ? 70.242  -27.062 -14.111 1.00 52.07  ?  6858 ALA   B H      1 
ATOM   969  H  HA     . ALA   A  1 60  ? 70.187  -27.414 -16.739 1.00 51.70  ?  6858 ALA   B HA     1 
ATOM   970  H  HB1    . ALA   A  1 60  ? 69.214  -25.273 -16.769 1.00 52.11  ?  6858 ALA   B HB1    1 
ATOM   971  H  HB2    . ALA   A  1 60  ? 68.460  -26.242 -15.761 1.00 52.11  ?  6858 ALA   B HB2    1 
ATOM   972  H  HB3    . ALA   A  1 60  ? 69.476  -25.154 -15.207 1.00 52.11  ?  6858 ALA   B HB3    1 
ATOM   973  N  N      . VAL   A  1 61  ? 72.172  -26.328 -17.688 1.00 43.38  ?  6859 VAL   B N      1 
ATOM   974  C  CA     . VAL   A  1 61  ? 73.399  -25.736 -18.209 1.00 45.31  ?  6859 VAL   B CA     1 
ATOM   975  C  C      . VAL   A  1 61  ? 73.089  -25.102 -19.561 1.00 48.22  ?  6859 VAL   B C      1 
ATOM   976  O  O      . VAL   A  1 61  ? 73.427  -25.669 -20.613 1.00 43.73  ?  6859 VAL   B O      1 
ATOM   977  C  CB     . VAL   A  1 61  ? 74.519  -26.781 -18.316 1.00 40.04  ?  6859 VAL   B CB     1 
ATOM   978  C  CG1    . VAL   A  1 61  ? 75.830  -26.126 -18.658 1.00 42.08  ?  6859 VAL   B CG1    1 
ATOM   979  C  CG2    . VAL   A  1 61  ? 74.635  -27.538 -16.993 1.00 43.38  ?  6859 VAL   B CG2    1 
ATOM   980  H  H      . VAL   A  1 61  ? 71.771  -26.840 -18.250 1.00 52.58  ?  6859 VAL   B H      1 
ATOM   981  H  HA     . VAL   A  1 61  ? 73.703  -25.039 -17.608 1.00 54.89  ?  6859 VAL   B HA     1 
ATOM   982  H  HB     . VAL   A  1 61  ? 74.306  -27.407 -19.026 1.00 48.57  ?  6859 VAL   B HB     1 
ATOM   983  H  HG11   . VAL   A  1 61  ? 76.524  -26.802 -18.681 1.00 51.02  ?  6859 VAL   B HG11   1 
ATOM   984  H  HG12   . VAL   A  1 61  ? 75.753  -25.700 -19.526 1.00 51.02  ?  6859 VAL   B HG12   1 
ATOM   985  H  HG13   . VAL   A  1 61  ? 76.037  -25.462 -17.981 1.00 51.02  ?  6859 VAL   B HG13   1 
ATOM   986  H  HG21   . VAL   A  1 61  ? 75.412  -28.117 -17.027 1.00 52.58  ?  6859 VAL   B HG21   1 
ATOM   987  H  HG22   . VAL   A  1 61  ? 74.731  -26.897 -16.270 1.00 52.58  ?  6859 VAL   B HG22   1 
ATOM   988  H  HG23   . VAL   A  1 61  ? 73.833  -28.067 -16.860 1.00 52.58  ?  6859 VAL   B HG23   1 
ATOM   989  N  N      . PRO   A  1 62  ? 72.449  -23.938 -19.578 1.00 44.45  ?  6860 PRO   B N      1 
ATOM   990  C  CA     . PRO   A  1 62  ? 72.129  -23.279 -20.848 1.00 45.34  ?  6860 PRO   B CA     1 
ATOM   991  C  C      . PRO   A  1 62  ? 73.375  -22.702 -21.506 1.00 47.98  ?  6860 PRO   B C      1 
ATOM   992  O  O      . PRO   A  1 62  ? 74.449  -22.586 -20.910 1.00 47.67  ?  6860 PRO   B O      1 
ATOM   993  C  CB     . PRO   A  1 62  ? 71.160  -22.168 -20.430 1.00 44.63  ?  6860 PRO   B CB     1 
ATOM   994  C  CG     . PRO   A  1 62  ? 71.538  -21.855 -18.995 1.00 46.94  ?  6860 PRO   B CG     1 
ATOM   995  C  CD     . PRO   A  1 62  ? 72.037  -23.148 -18.401 1.00 45.92  ?  6860 PRO   B CD     1 
ATOM   996  H  HA     . PRO   A  1 62  ? 71.691  -23.893 -21.457 1.00 54.93  ?  6860 PRO   B HA     1 
ATOM   997  H  HB2    . PRO   A  1 62  ? 71.278  -21.392 -21.000 1.00 54.08  ?  6860 PRO   B HB2    1 
ATOM   998  H  HB3    . PRO   A  1 62  ? 70.245  -22.486 -20.488 1.00 54.08  ?  6860 PRO   B HB3    1 
ATOM   999  H  HG2    . PRO   A  1 62  ? 72.235  -21.181 -18.982 1.00 56.85  ?  6860 PRO   B HG2    1 
ATOM   1000 H  HG3    . PRO   A  1 62  ? 70.758  -21.536 -18.515 1.00 56.85  ?  6860 PRO   B HG3    1 
ATOM   1001 H  HD2    . PRO   A  1 62  ? 72.792  -22.987 -17.814 1.00 55.63  ?  6860 PRO   B HD2    1 
ATOM   1002 H  HD3    . PRO   A  1 62  ? 71.329  -23.599 -17.916 1.00 55.63  ?  6860 PRO   B HD3    1 
ATOM   1003 N  N      . TYR   A  1 63  ? 73.206  -22.332 -22.776 1.00 53.07  ?  6861 TYR   B N      1 
ATOM   1004 C  CA     . TYR   A  1 63  ? 74.117  -21.398 -23.429 1.00 49.10  ?  6861 TYR   B CA     1 
ATOM   1005 C  C      . TYR   A  1 63  ? 74.021  -20.045 -22.732 1.00 52.64  ?  6861 TYR   B C      1 
ATOM   1006 O  O      . TYR   A  1 63  ? 72.976  -19.685 -22.177 1.00 51.55  ?  6861 TYR   B O      1 
ATOM   1007 C  CB     . TYR   A  1 63  ? 73.755  -21.272 -24.909 1.00 53.29  ?  6861 TYR   B CB     1 
ATOM   1008 C  CG     . TYR   A  1 63  ? 74.005  -22.526 -25.746 1.00 50.95  ?  6861 TYR   B CG     1 
ATOM   1009 C  CD1    . TYR   A  1 63  ? 75.292  -22.909 -26.108 1.00 62.17  ?  6861 TYR   B CD1    1 
ATOM   1010 C  CD2    . TYR   A  1 63  ? 72.954  -23.318 -26.185 1.00 53.73  ?  6861 TYR   B CD2    1 
ATOM   1011 C  CE1    . TYR   A  1 63  ? 75.519  -24.039 -26.882 1.00 66.19  ?  6861 TYR   B CE1    1 
ATOM   1012 C  CE2    . TYR   A  1 63  ? 73.178  -24.457 -26.957 1.00 54.01  ?  6861 TYR   B CE2    1 
ATOM   1013 C  CZ     . TYR   A  1 63  ? 74.458  -24.811 -27.298 1.00 56.01  ?  6861 TYR   B CZ     1 
ATOM   1014 O  OH     . TYR   A  1 63  ? 74.677  -25.936 -28.064 1.00 69.56  ?  6861 TYR   B OH     1 
ATOM   1015 H  H      . TYR   A  1 63  ? 72.568  -22.609 -23.282 1.00 64.20  ?  6861 TYR   B H      1 
ATOM   1016 H  HA     . TYR   A  1 63  ? 75.034  -21.711 -23.378 1.00 59.44  ?  6861 TYR   B HA     1 
ATOM   1017 H  HB2    . TYR   A  1 63  ? 72.811  -21.061 -24.977 1.00 64.47  ?  6861 TYR   B HB2    1 
ATOM   1018 H  HB3    . TYR   A  1 63  ? 74.284  -20.556 -25.294 1.00 64.47  ?  6861 TYR   B HB3    1 
ATOM   1019 H  HD1    . TYR   A  1 63  ? 76.016  -22.397 -25.826 1.00 75.12  ?  6861 TYR   B HD1    1 
ATOM   1020 H  HD2    . TYR   A  1 63  ? 72.083  -23.085 -25.959 1.00 64.99  ?  6861 TYR   B HD2    1 
ATOM   1021 H  HE1    . TYR   A  1 63  ? 76.387  -24.275 -27.118 1.00 79.95  ?  6861 TYR   B HE1    1 
ATOM   1022 H  HE2    . TYR   A  1 63  ? 72.461  -24.975 -27.240 1.00 65.34  ?  6861 TYR   B HE2    1 
ATOM   1023 H  HH     . TYR   A  1 63  ? 73.953  -26.341 -28.193 1.00 83.99  ?  6861 TYR   B HH     1 
ATOM   1024 N  N      A ASN   A  1 64  ? 75.139  -19.313 -22.750 0.57 53.72  ?  6862 ASN   B N      1 
ATOM   1025 N  N      B ASN   A  1 64  ? 75.110  -19.282 -22.753 0.43 53.76  ?  6862 ASN   B N      1 
ATOM   1026 C  CA     A ASN   A  1 64  ? 75.256  -18.021 -22.075 0.57 56.45  ?  6862 ASN   B CA     1 
ATOM   1027 C  CA     B ASN   A  1 64  ? 75.146  -17.977 -22.083 0.43 56.37  ?  6862 ASN   B CA     1 
ATOM   1028 C  C      A ASN   A  1 64  ? 74.806  -18.124 -20.622 0.57 50.56  ?  6862 ASN   B C      1 
ATOM   1029 C  C      B ASN   A  1 64  ? 74.799  -18.108 -20.599 0.43 50.61  ?  6862 ASN   B C      1 
ATOM   1030 O  O      A ASN   A  1 64  ? 74.064  -17.290 -20.097 0.57 53.22  ?  6862 ASN   B O      1 
ATOM   1031 O  O      B ASN   A  1 64  ? 74.101  -17.269 -20.025 0.43 53.24  ?  6862 ASN   B O      1 
ATOM   1032 C  CB     A ASN   A  1 64  ? 74.477  -16.959 -22.844 0.57 57.34  ?  6862 ASN   B CB     1 
ATOM   1033 C  CB     B ASN   A  1 64  ? 74.207  -16.978 -22.772 0.43 57.42  ?  6862 ASN   B CB     1 
ATOM   1034 C  CG     A ASN   A  1 64  ? 75.044  -16.724 -24.231 0.57 58.49  ?  6862 ASN   B CG     1 
ATOM   1035 C  CG     B ASN   A  1 64  ? 74.491  -15.533 -22.377 0.43 60.96  ?  6862 ASN   B CG     1 
ATOM   1036 O  OD1    A ASN   A  1 64  ? 76.262  -16.661 -24.412 0.57 53.86  ?  6862 ASN   B OD1    1 
ATOM   1037 O  OD1    B ASN   A  1 64  ? 75.514  -14.960 -22.756 0.43 65.66  ?  6862 ASN   B OD1    1 
ATOM   1038 N  ND2    A ASN   A  1 64  ? 74.163  -16.620 -25.220 0.57 58.61  ?  6862 ASN   B ND2    1 
ATOM   1039 N  ND2    B ASN   A  1 64  ? 73.584  -14.938 -21.614 0.43 62.13  ?  6862 ASN   B ND2    1 
ATOM   1040 H  H      A ASN   A  1 64  ? 75.859  -19.551 -23.156 0.57 64.98  ?  6862 ASN   B H      1 
ATOM   1041 H  H      B ASN   A  1 64  ? 75.844  -19.495 -23.148 0.43 65.04  ?  6862 ASN   B H      1 
ATOM   1042 H  HA     A ASN   A  1 64  ? 76.187  -17.750 -22.057 0.57 68.26  ?  6862 ASN   B HA     1 
ATOM   1043 H  HA     B ASN   A  1 64  ? 76.049  -17.628 -22.141 0.43 68.17  ?  6862 ASN   B HA     1 
ATOM   1044 H  HB2    A ASN   A  1 64  ? 73.556  -17.247 -22.939 0.57 69.33  ?  6862 ASN   B HB2    1 
ATOM   1045 H  HB2    B ASN   A  1 64  ? 74.315  -17.054 -23.733 0.43 69.43  ?  6862 ASN   B HB2    1 
ATOM   1046 H  HB3    A ASN   A  1 64  ? 74.515  -16.122 -22.356 0.57 69.33  ?  6862 ASN   B HB3    1 
ATOM   1047 H  HB3    B ASN   A  1 64  ? 73.291  -17.182 -22.524 0.43 69.43  ?  6862 ASN   B HB3    1 
ATOM   1048 H  HD21   A ASN   A  1 64  ? 74.434  -16.486 -26.025 0.57 70.86  ?  6862 ASN   B HD21   1 
ATOM   1049 H  HD21   B ASN   A  1 64  ? 73.699  -14.123 -21.365 0.43 75.07  ?  6862 ASN   B HD21   1 
ATOM   1050 H  HD22   A ASN   A  1 64  ? 73.322  -16.686 -25.055 0.57 70.86  ?  6862 ASN   B HD22   1 
ATOM   1051 H  HD22   B ASN   A  1 64  ? 72.880  -15.367 -21.369 0.43 75.07  ?  6862 ASN   B HD22   1 
ATOM   1052 N  N      . MET   A  1 65  ? 75.284  -19.179 -19.976 1.00 51.99  ?  6863 MET   B N      1 
ATOM   1053 C  CA     . MET   A  1 65  ? 74.989  -19.434 -18.575 1.00 48.26  ?  6863 MET   B CA     1 
ATOM   1054 C  C      . MET   A  1 65  ? 75.571  -18.342 -17.692 1.00 48.28  ?  6863 MET   B C      1 
ATOM   1055 O  O      . MET   A  1 65  ? 76.630  -17.778 -17.978 1.00 46.50  ?  6863 MET   B O      1 
ATOM   1056 C  CB     . MET   A  1 65  ? 75.573  -20.788 -18.183 1.00 48.20  ?  6863 MET   B CB     1 
ATOM   1057 C  CG     . MET   A  1 65  ? 75.242  -21.284 -16.805 1.00 43.56  ?  6863 MET   B CG     1 
ATOM   1058 S  SD     . MET   A  1 65  ? 75.959  -22.920 -16.539 1.00 46.98  ?  6863 MET   B SD     1 
ATOM   1059 C  CE     . MET   A  1 65  ? 75.326  -23.305 -14.907 1.00 38.31  ?  6863 MET   B CE     1 
ATOM   1060 H  H      A MET   A  1 65  ? 75.792  -19.774 -20.333 0.57 62.91  ?  6863 MET   B H      1 
ATOM   1061 H  H      B MET   A  1 65  ? 75.787  -19.772 -20.344 0.43 62.91  ?  6863 MET   B H      1 
ATOM   1062 H  HA     . MET   A  1 65  ? 74.028  -19.455 -18.441 1.00 58.44  ?  6863 MET   B HA     1 
ATOM   1063 H  HB2    . MET   A  1 65  ? 75.246  -21.451 -18.811 1.00 58.36  ?  6863 MET   B HB2    1 
ATOM   1064 H  HB3    . MET   A  1 65  ? 76.540  -20.727 -18.239 1.00 58.36  ?  6863 MET   B HB3    1 
ATOM   1065 H  HG2    . MET   A  1 65  ? 75.606  -20.675 -16.144 1.00 52.80  ?  6863 MET   B HG2    1 
ATOM   1066 H  HG3    . MET   A  1 65  ? 74.279  -21.347 -16.704 1.00 52.80  ?  6863 MET   B HG3    1 
ATOM   1067 H  HE1    . MET   A  1 65  ? 75.644  -24.183 -14.644 1.00 46.50  ?  6863 MET   B HE1    1 
ATOM   1068 H  HE2    . MET   A  1 65  ? 75.644  -22.637 -14.280 1.00 46.50  ?  6863 MET   B HE2    1 
ATOM   1069 H  HE3    . MET   A  1 65  ? 74.357  -23.298 -14.935 1.00 46.50  ?  6863 MET   B HE3    1 
ATOM   1070 N  N      . ARG   A  1 66  ? 74.883  -18.080 -16.588 1.00 49.12  ?  6864 ARG   B N      1 
ATOM   1071 C  CA     . ARG   A  1 66  ? 75.203  -16.986 -15.685 1.00 47.87  ?  6864 ARG   B CA     1 
ATOM   1072 C  C      . ARG   A  1 66  ? 75.326  -17.532 -14.278 1.00 46.07  ?  6864 ARG   B C      1 
ATOM   1073 O  O      . ARG   A  1 66  ? 74.370  -18.100 -13.739 1.00 44.13  ?  6864 ARG   B O      1 
ATOM   1074 C  CB     . ARG   A  1 66  ? 74.148  -15.884 -15.763 1.00 49.18  ?  6864 ARG   B CB     1 
ATOM   1075 C  CG     . ARG   A  1 66  ? 73.559  -15.740 -17.141 1.00 53.67  ?  6864 ARG   B CG     1 
ATOM   1076 C  CD     . ARG   A  1 66  ? 72.241  -15.029 -17.074 1.00 52.35  ?  6864 ARG   B CD     1 
ATOM   1077 N  NE     . ARG   A  1 66  ? 71.976  -14.196 -18.239 1.00 51.40  ?  6864 ARG   B NE     1 
ATOM   1078 C  CZ     . ARG   A  1 66  ? 71.003  -13.295 -18.293 1.00 55.85  ?  6864 ARG   B CZ     1 
ATOM   1079 N  NH1    . ARG   A  1 66  ? 70.134  -13.159 -17.305 1.00 52.13  ?  6864 ARG   B NH1    1 
ATOM   1080 N  NH2    . ARG   A  1 66  ? 70.888  -12.519 -19.372 1.00 68.20  ?  6864 ARG   B NH2    1 
ATOM   1081 H  H      . ARG   A  1 66  ? 74.202  -18.540 -16.333 1.00 59.47  ?  6864 ARG   B H      1 
ATOM   1082 H  HA     . ARG   A  1 66  ? 76.059  -16.601 -15.929 1.00 57.97  ?  6864 ARG   B HA     1 
ATOM   1083 H  HB2    . ARG   A  1 66  ? 73.427  -16.092 -15.148 1.00 59.54  ?  6864 ARG   B HB2    1 
ATOM   1084 H  HB3    . ARG   A  1 66  ? 74.556  -15.038 -15.521 1.00 59.54  ?  6864 ARG   B HB3    1 
ATOM   1085 H  HG2    . ARG   A  1 66  ? 74.161  -15.224 -17.699 1.00 64.93  ?  6864 ARG   B HG2    1 
ATOM   1086 H  HG3    . ARG   A  1 66  ? 73.418  -16.618 -17.528 1.00 64.93  ?  6864 ARG   B HG3    1 
ATOM   1087 H  HD2    . ARG   A  1 66  ? 71.532  -15.687 -17.011 1.00 63.34  ?  6864 ARG   B HD2    1 
ATOM   1088 H  HD3    . ARG   A  1 66  ? 72.233  -14.456 -16.291 1.00 63.34  ?  6864 ARG   B HD3    1 
ATOM   1089 H  HE     . ARG   A  1 66  ? 72.477  -14.293 -18.931 1.00 62.21  ?  6864 ARG   B HE     1 
ATOM   1090 H  HH11   . ARG   A  1 66  ? 70.193  -13.661 -16.609 1.00 63.08  ?  6864 ARG   B HH11   1 
ATOM   1091 H  HH12   . ARG   A  1 66  ? 69.511  -12.569 -17.359 1.00 63.08  ?  6864 ARG   B HH12   1 
ATOM   1092 H  HH21   . ARG   A  1 66  ? 71.441  -12.605 -20.024 1.00 82.36  ?  6864 ARG   B HH21   1 
ATOM   1093 H  HH22   . ARG   A  1 66  ? 70.260  -11.932 -19.414 1.00 82.36  ?  6864 ARG   B HH22   1 
ATOM   1094 N  N      . VAL   A  1 67  ? 76.512  -17.384 -13.705 1.00 40.17  ?  6865 VAL   B N      1 
ATOM   1095 C  CA     . VAL   A  1 67  ? 76.839  -17.919 -12.400 1.00 35.24  ?  6865 VAL   B CA     1 
ATOM   1096 C  C      . VAL   A  1 67  ? 77.394  -16.800 -11.539 1.00 40.43  ?  6865 VAL   B C      1 
ATOM   1097 O  O      . VAL   A  1 67  ? 78.216  -15.998 -11.997 1.00 43.45  ?  6865 VAL   B O      1 
ATOM   1098 C  CB     . VAL   A  1 67  ? 77.851  -19.073 -12.504 1.00 36.58  ?  6865 VAL   B CB     1 
ATOM   1099 C  CG1    . VAL   A  1 67  ? 78.084  -19.691 -11.123 1.00 41.27  ?  6865 VAL   B CG1    1 
ATOM   1100 C  CG2    . VAL   A  1 67  ? 77.358  -20.117 -13.476 1.00 41.26  ?  6865 VAL   B CG2    1 
ATOM   1101 H  H      . VAL   A  1 67  ? 77.166  -16.960 -14.070 1.00 48.72  ?  6865 VAL   B H      1 
ATOM   1102 H  HA     . VAL   A  1 67  ? 76.032  -18.254 -11.979 1.00 42.81  ?  6865 VAL   B HA     1 
ATOM   1103 H  HB     . VAL   A  1 67  ? 78.697  -18.729 -12.833 1.00 44.41  ?  6865 VAL   B HB     1 
ATOM   1104 H  HG11   . VAL   A  1 67  ? 78.610  -20.500 -11.224 1.00 50.05  ?  6865 VAL   B HG11   1 
ATOM   1105 H  HG12   . VAL   A  1 67  ? 78.560  -19.054 -10.568 1.00 50.05  ?  6865 VAL   B HG12   1 
ATOM   1106 H  HG13   . VAL   A  1 67  ? 77.226  -19.902 -10.723 1.00 50.05  ?  6865 VAL   B HG13   1 
ATOM   1107 H  HG21   . VAL   A  1 67  ? 77.898  -20.917 -13.380 1.00 50.04  ?  6865 VAL   B HG21   1 
ATOM   1108 H  HG22   . VAL   A  1 67  ? 76.430  -20.318 -13.279 1.00 50.04  ?  6865 VAL   B HG22   1 
ATOM   1109 H  HG23   . VAL   A  1 67  ? 77.438  -19.771 -14.379 1.00 50.04  ?  6865 VAL   B HG23   1 
ATOM   1110 N  N      . ILE   A  1 68  ? 76.951  -16.749 -10.284 1.00 42.09  ?  6866 ILE   B N      1 
ATOM   1111 C  CA     . ILE   A  1 68  ? 77.452  -15.781 -9.316  1.00 36.68  ?  6866 ILE   B CA     1 
ATOM   1112 C  C      . ILE   A  1 68  ? 77.932  -16.506 -8.067  1.00 35.64  ?  6866 ILE   B C      1 
ATOM   1113 O  O      . ILE   A  1 68  ? 77.306  -17.465 -7.603  1.00 38.47  ?  6866 ILE   B O      1 
ATOM   1114 C  CB     . ILE   A  1 68  ? 76.383  -14.728 -8.969  1.00 39.04  ?  6866 ILE   B CB     1 
ATOM   1115 C  CG1    . ILE   A  1 68  ? 77.001  -13.643 -8.088  1.00 38.55  ?  6866 ILE   B CG1    1 
ATOM   1116 C  CG2    . ILE   A  1 68  ? 75.163  -15.373 -8.293  1.00 44.39  ?  6866 ILE   B CG2    1 
ATOM   1117 C  CD1    . ILE   A  1 68  ? 76.262  -12.330 -8.161  1.00 39.40  ?  6866 ILE   B CD1    1 
ATOM   1118 H  H      . ILE   A  1 68  ? 76.351  -17.276 -9.966  1.00 51.03  ?  6866 ILE   B H      1 
ATOM   1119 H  HA     . ILE   A  1 68  ? 78.218  -15.327 -9.699  1.00 44.54  ?  6866 ILE   B HA     1 
ATOM   1120 H  HB     . ILE   A  1 68  ? 76.069  -14.320 -9.792  1.00 47.37  ?  6866 ILE   B HB     1 
ATOM   1121 H  HG12   . ILE   A  1 68  ? 76.989  -13.942 -7.165  1.00 46.78  ?  6866 ILE   B HG12   1 
ATOM   1122 H  HG13   . ILE   A  1 68  ? 77.915  -13.488 -8.374  1.00 46.78  ?  6866 ILE   B HG13   1 
ATOM   1123 H  HG21   . ILE   A  1 68  ? 74.474  -14.700 -8.176  1.00 53.79  ?  6866 ILE   B HG21   1 
ATOM   1124 H  HG22   . ILE   A  1 68  ? 74.832  -16.091 -8.856  1.00 53.79  ?  6866 ILE   B HG22   1 
ATOM   1125 H  HG23   . ILE   A  1 68  ? 75.430  -15.726 -7.430  1.00 53.79  ?  6866 ILE   B HG23   1 
ATOM   1126 H  HD11   . ILE   A  1 68  ? 76.703  -11.687 -7.583  1.00 47.80  ?  6866 ILE   B HD11   1 
ATOM   1127 H  HD12   . ILE   A  1 68  ? 76.273  -12.012 -9.078  1.00 47.80  ?  6866 ILE   B HD12   1 
ATOM   1128 H  HD13   . ILE   A  1 68  ? 75.348  -12.466 -7.868  1.00 47.80  ?  6866 ILE   B HD13   1 
ATOM   1129 N  N      . HIS   A  1 69  ? 79.040  -16.016 -7.527  1.00 42.12  ?  6867 HIS   B N      1 
ATOM   1130 C  CA     . HIS   A  1 69  ? 79.844  -16.677 -6.505  1.00 41.57  ?  6867 HIS   B CA     1 
ATOM   1131 C  C      . HIS   A  1 69  ? 80.100  -15.670 -5.391  1.00 38.35  ?  6867 HIS   B C      1 
ATOM   1132 O  O      . HIS   A  1 69  ? 80.887  -14.730 -5.562  1.00 41.02  ?  6867 HIS   B O      1 
ATOM   1133 C  CB     . HIS   A  1 69  ? 81.155  -17.183 -7.114  1.00 37.91  ?  6867 HIS   B CB     1 
ATOM   1134 C  CG     . HIS   A  1 69  ? 82.068  -17.886 -6.160  1.00 33.95  ?  6867 HIS   B CG     1 
ATOM   1135 N  ND1    . HIS   A  1 69  ? 83.427  -17.967 -6.371  1.00 34.83  ?  6867 HIS   B ND1    1 
ATOM   1136 C  CD2    . HIS   A  1 69  ? 81.829  -18.546 -5.003  1.00 33.14  ?  6867 HIS   B CD2    1 
ATOM   1137 C  CE1    . HIS   A  1 69  ? 83.987  -18.628 -5.374  1.00 32.94  ?  6867 HIS   B CE1    1 
ATOM   1138 N  NE2    . HIS   A  1 69  ? 83.039  -18.998 -4.536  1.00 37.43  ?  6867 HIS   B NE2    1 
ATOM   1139 H  H      . HIS   A  1 69  ? 79.369  -15.254 -7.750  1.00 51.07  ?  6867 HIS   B H      1 
ATOM   1140 H  HA     . HIS   A  1 69  ? 79.365  -17.431 -6.126  1.00 50.40  ?  6867 HIS   B HA     1 
ATOM   1141 H  HB2    . HIS   A  1 69  ? 80.942  -17.807 -7.825  1.00 46.02  ?  6867 HIS   B HB2    1 
ATOM   1142 H  HB3    . HIS   A  1 69  ? 81.639  -16.423 -7.474  1.00 46.02  ?  6867 HIS   B HB3    1 
ATOM   1143 H  HD1    . HIS   A  1 69  ? 83.845  -17.638 -7.046  1.00 42.31  ?  6867 HIS   B HD1    1 
ATOM   1144 H  HD2    . HIS   A  1 69  ? 81.001  -18.670 -4.599  1.00 40.29  ?  6867 HIS   B HD2    1 
ATOM   1145 H  HE1    . HIS   A  1 69  ? 84.896  -18.803 -5.280  1.00 40.05  ?  6867 HIS   B HE1    1 
ATOM   1146 N  N      . PHE   A  1 70  ? 79.447  -15.866 -4.253  1.00 41.56  ?  6868 PHE   B N      1 
ATOM   1147 C  CA     . PHE   A  1 70  ? 79.628  -14.987 -3.106  1.00 40.05  ?  6868 PHE   B CA     1 
ATOM   1148 C  C      . PHE   A  1 70  ? 80.652  -15.558 -2.128  1.00 37.83  ?  6868 PHE   B C      1 
ATOM   1149 O  O      . PHE   A  1 70  ? 80.764  -16.773 -1.958  1.00 38.68  ?  6868 PHE   B O      1 
ATOM   1150 C  CB     . PHE   A  1 70  ? 78.319  -14.766 -2.351  1.00 41.33  ?  6868 PHE   B CB     1 
ATOM   1151 C  CG     . PHE   A  1 70  ? 77.303  -13.989 -3.102  1.00 38.44  ?  6868 PHE   B CG     1 
ATOM   1152 C  CD1    . PHE   A  1 70  ? 77.349  -12.615 -3.132  1.00 39.91  ?  6868 PHE   B CD1    1 
ATOM   1153 C  CD2    . PHE   A  1 70  ? 76.289  -14.629 -3.767  1.00 39.24  ?  6868 PHE   B CD2    1 
ATOM   1154 C  CE1    . PHE   A  1 70  ? 76.396  -11.894 -3.825  1.00 41.82  ?  6868 PHE   B CE1    1 
ATOM   1155 C  CE2    . PHE   A  1 70  ? 75.340  -13.911 -4.462  1.00 40.68  ?  6868 PHE   B CE2    1 
ATOM   1156 C  CZ     . PHE   A  1 70  ? 75.393  -12.541 -4.489  1.00 41.44  ?  6868 PHE   B CZ     1 
ATOM   1157 H  H      . PHE   A  1 70  ? 78.889  -16.507 -4.120  1.00 50.40  ?  6868 PHE   B H      1 
ATOM   1158 H  HA     . PHE   A  1 70  ? 79.950  -14.134 -3.438  1.00 48.58  ?  6868 PHE   B HA     1 
ATOM   1159 H  HB2    . PHE   A  1 70  ? 77.932  -15.631 -2.143  1.00 50.12  ?  6868 PHE   B HB2    1 
ATOM   1160 H  HB3    . PHE   A  1 70  ? 78.511  -14.283 -1.532  1.00 50.12  ?  6868 PHE   B HB3    1 
ATOM   1161 H  HD1    . PHE   A  1 70  ? 78.028  -12.167 -2.681  1.00 48.42  ?  6868 PHE   B HD1    1 
ATOM   1162 H  HD2    . PHE   A  1 70  ? 76.241  -15.558 -3.749  1.00 47.61  ?  6868 PHE   B HD2    1 
ATOM   1163 H  HE1    . PHE   A  1 70  ? 76.438  -10.965 -3.840  1.00 50.70  ?  6868 PHE   B HE1    1 
ATOM   1164 H  HE2    . PHE   A  1 70  ? 74.662  -14.357 -4.916  1.00 49.34  ?  6868 PHE   B HE2    1 
ATOM   1165 H  HZ     . PHE   A  1 70  ? 74.750  -12.056 -4.954  1.00 50.24  ?  6868 PHE   B HZ     1 
ATOM   1166 N  N      . GLY   A  1 71  ? 81.367  -14.665 -1.446  1.00 43.95  ?  6869 GLY   B N      1 
ATOM   1167 C  CA     . GLY   A  1 71  ? 82.388  -15.090 -0.501  1.00 38.97  ?  6869 GLY   B CA     1 
ATOM   1168 C  C      . GLY   A  1 71  ? 83.624  -15.638 -1.179  1.00 38.18  ?  6869 GLY   B C      1 
ATOM   1169 O  O      . GLY   A  1 71  ? 84.223  -16.607 -0.689  1.00 40.17  ?  6869 GLY   B O      1 
ATOM   1170 H  H      . GLY   A  1 71  ? 81.279  -13.813 -1.514  1.00 53.27  ?  6869 GLY   B H      1 
ATOM   1171 H  HA2    . GLY   A  1 71  ? 82.651  -14.333 0.046   1.00 47.28  ?  6869 GLY   B HA2    1 
ATOM   1172 H  HA3    . GLY   A  1 71  ? 82.023  -15.783 0.072   1.00 47.28  ?  6869 GLY   B HA3    1 
ATOM   1173 N  N      . ALA   A  1 72  ? 84.013  -15.044 -2.304  1.00 44.07  ?  6870 ALA   B N      1 
ATOM   1174 C  CA     . ALA   A  1 72  ? 84.984  -15.635 -3.209  1.00 38.17  ?  6870 ALA   B CA     1 
ATOM   1175 C  C      . ALA   A  1 72  ? 86.427  -15.293 -2.857  1.00 39.50  ?  6870 ALA   B C      1 
ATOM   1176 O  O      . ALA   A  1 72  ? 87.333  -15.925 -3.402  1.00 43.09  ?  6870 ALA   B O      1 
ATOM   1177 C  CB     . ALA   A  1 72  ? 84.700  -15.209 -4.659  1.00 37.53  ?  6870 ALA   B CB     1 
ATOM   1178 H  H      . ALA   A  1 72  ? 83.721  -14.279 -2.568  1.00 53.40  ?  6870 ALA   B H      1 
ATOM   1179 H  HA     . ALA   A  1 72  ? 84.891  -16.599 -3.160  1.00 46.32  ?  6870 ALA   B HA     1 
ATOM   1180 H  HB1    . ALA   A  1 72  ? 85.368  -15.604 -5.241  1.00 45.55  ?  6870 ALA   B HB1    1 
ATOM   1181 H  HB2    . ALA   A  1 72  ? 83.816  -15.518 -4.911  1.00 45.55  ?  6870 ALA   B HB2    1 
ATOM   1182 H  HB3    . ALA   A  1 72  ? 84.741  -14.241 -4.717  1.00 45.55  ?  6870 ALA   B HB3    1 
ATOM   1183 N  N      . GLY   A  1 73  ? 86.672  -14.332 -1.972  1.00 44.22  ?  6871 GLY   B N      1 
ATOM   1184 C  CA     . GLY   A  1 73  ? 88.030  -13.968 -1.621  1.00 43.52  ?  6871 GLY   B CA     1 
ATOM   1185 C  C      . GLY   A  1 73  ? 88.585  -14.853 -0.517  1.00 44.26  ?  6871 GLY   B C      1 
ATOM   1186 O  O      . GLY   A  1 73  ? 87.865  -15.261 0.382   1.00 56.47  ?  6871 GLY   B O      1 
ATOM   1187 H  H      . GLY   A  1 73  ? 86.067  -13.878 -1.563  1.00 53.59  ?  6871 GLY   B H      1 
ATOM   1188 H  HA2    . GLY   A  1 73  ? 88.600  -14.056 -2.401  1.00 52.74  ?  6871 GLY   B HA2    1 
ATOM   1189 H  HA3    . GLY   A  1 73  ? 88.051  -13.047 -1.318  1.00 52.74  ?  6871 GLY   B HA3    1 
ATOM   1190 N  N      . SER   A  1 74  ? 89.886  -15.119 -0.573  1.00 52.06  ?  6872 SER   B N      1 
ATOM   1191 C  CA     . SER   A  1 74  ? 90.574  -15.804 0.512   1.00 50.75  ?  6872 SER   B CA     1 
ATOM   1192 C  C      . SER   A  1 74  ? 91.376  -14.792 1.331   1.00 49.86  ?  6872 SER   B C      1 
ATOM   1193 O  O      . SER   A  1 74  ? 91.523  -13.627 0.955   1.00 49.96  ?  6872 SER   B O      1 
ATOM   1194 C  CB     . SER   A  1 74  ? 91.497  -16.898 -0.024  1.00 48.32  ?  6872 SER   B CB     1 
ATOM   1195 O  OG     . SER   A  1 74  ? 92.598  -16.342 -0.716  1.00 47.07  ?  6872 SER   B OG     1 
ATOM   1196 H  H      . SER   A  1 74  ? 90.394  -14.910 -1.235  1.00 62.99  ?  6872 SER   B H      1 
ATOM   1197 H  HA     . SER   A  1 74  ? 89.918  -16.229 1.086   1.00 61.42  ?  6872 SER   B HA     1 
ATOM   1198 H  HB2    . SER   A  1 74  ? 91.826  -17.425 0.721   1.00 58.50  ?  6872 SER   B HB2    1 
ATOM   1199 H  HB3    . SER   A  1 74  ? 90.995  -17.463 -0.633  1.00 58.50  ?  6872 SER   B HB3    1 
ATOM   1200 H  HG     . SER   A  1 74  ? 92.327  -15.835 -1.329  1.00 57.01  ?  6872 SER   B HG     1 
ATOM   1201 N  N      . ASP   A  1 75  ? 91.921  -15.257 2.458   1.00 55.82  ?  6873 ASP   B N      1 
ATOM   1202 C  CA     . ASP   A  1 75  ? 92.856  -14.422 3.204   1.00 50.26  ?  6873 ASP   B CA     1 
ATOM   1203 C  C      . ASP   A  1 75  ? 94.176  -14.240 2.483   1.00 55.24  ?  6873 ASP   B C      1 
ATOM   1204 O  O      . ASP   A  1 75  ? 95.034  -13.503 2.978   1.00 63.78  ?  6873 ASP   B O      1 
ATOM   1205 C  CB     . ASP   A  1 75  ? 93.061  -14.986 4.624   1.00 57.10  ?  6873 ASP   B CB     1 
ATOM   1206 C  CG     . ASP   A  1 75  ? 93.591  -16.422 4.656   1.00 63.36  ?  6873 ASP   B CG     1 
ATOM   1207 O  OD1    . ASP   A  1 75  ? 93.773  -17.066 3.598   1.00 68.63  ?  6873 ASP   B OD1    1 
ATOM   1208 O  OD2    . ASP   A  1 75  ? 93.804  -16.916 5.788   1.00 65.43  ?  6873 ASP   B OD2    1 
ATOM   1209 H  H      . ASP   A  1 75  ? 91.767  -16.031 2.799   1.00 67.51  ?  6873 ASP   B H      1 
ATOM   1210 H  HA     . ASP   A  1 75  ? 92.473  -13.538 3.316   1.00 60.83  ?  6873 ASP   B HA     1 
ATOM   1211 H  HB2    . ASP   A  1 75  ? 93.701  -14.426 5.092   1.00 69.04  ?  6873 ASP   B HB2    1 
ATOM   1212 H  HB3    . ASP   A  1 75  ? 92.210  -14.976 5.089   1.00 69.04  ?  6873 ASP   B HB3    1 
ATOM   1213 N  N      . LYS   A  1 76  ? 94.339  -14.826 1.299   1.00 57.40  ?  6874 LYS   B N      1 
ATOM   1214 C  CA     . LYS   A  1 76  ? 95.571  -14.697 0.532   1.00 47.61  ?  6874 LYS   B CA     1 
ATOM   1215 C  C      . LYS   A  1 76  ? 95.478  -13.636 -0.562  1.00 49.30  ?  6874 LYS   B C      1 
ATOM   1216 O  O      . LYS   A  1 76  ? 96.494  -13.339 -1.204  1.00 57.64  ?  6874 LYS   B O      1 
ATOM   1217 C  CB     . LYS   A  1 76  ? 95.960  -16.051 -0.094  1.00 52.85  ?  6874 LYS   B CB     1 
ATOM   1218 C  CG     . LYS   A  1 76  ? 95.608  -17.307 0.741   1.00 68.90  ?  6874 LYS   B CG     1 
ATOM   1219 C  CD     . LYS   A  1 76  ? 95.146  -18.471 -0.132  1.00 67.98  ?  6874 LYS   B CD     1 
ATOM   1220 C  CE     . LYS   A  1 76  ? 95.005  -19.776 0.640   1.00 74.32  ?  6874 LYS   B CE     1 
ATOM   1221 N  NZ     . LYS   A  1 76  ? 96.235  -20.585 0.739   1.00 67.44  ?  6874 LYS   B NZ     1 
ATOM   1222 H  H      . LYS   A  1 76  ? 93.740  -15.309 0.914   1.00 69.40  ?  6874 LYS   B H      1 
ATOM   1223 H  HA     . LYS   A  1 76  ? 96.287  -14.442 1.134   1.00 57.66  ?  6874 LYS   B HA     1 
ATOM   1224 H  HB2    . LYS   A  1 76  ? 95.503  -16.135 -0.945  1.00 63.94  ?  6874 LYS   B HB2    1 
ATOM   1225 H  HB3    . LYS   A  1 76  ? 96.920  -16.057 -0.231  1.00 63.94  ?  6874 LYS   B HB3    1 
ATOM   1226 H  HG2    . LYS   A  1 76  ? 96.393  -17.593 1.233   1.00 83.20  ?  6874 LYS   B HG2    1 
ATOM   1227 H  HG3    . LYS   A  1 76  ? 94.891  -17.089 1.357   1.00 83.20  ?  6874 LYS   B HG3    1 
ATOM   1228 H  HD2    . LYS   A  1 76  ? 94.280  -18.255 -0.513  1.00 82.10  ?  6874 LYS   B HD2    1 
ATOM   1229 H  HD3    . LYS   A  1 76  ? 95.794  -18.612 -0.840  1.00 82.10  ?  6874 LYS   B HD3    1 
ATOM   1230 H  HE2    . LYS   A  1 76  ? 94.721  -19.568 1.544   1.00 89.70  ?  6874 LYS   B HE2    1 
ATOM   1231 H  HE3    . LYS   A  1 76  ? 94.335  -20.322 0.199   1.00 89.70  ?  6874 LYS   B HE3    1 
ATOM   1232 H  HZ1    . LYS   A  1 76  ? 96.464  -20.891 -0.065  1.00 81.44  ?  6874 LYS   B HZ1    1 
ATOM   1233 H  HZ2    . LYS   A  1 76  ? 96.901  -20.089 1.060   1.00 81.44  ?  6874 LYS   B HZ2    1 
ATOM   1234 H  HZ3    . LYS   A  1 76  ? 96.102  -21.277 1.284   1.00 81.44  ?  6874 LYS   B HZ3    1 
ATOM   1235 N  N      . GLY   A  1 77  ? 94.295  -13.070 -0.798  1.00 45.61  ?  6875 GLY   B N      1 
ATOM   1236 C  CA     . GLY   A  1 77  ? 94.109  -12.070 -1.824  1.00 42.46  ?  6875 GLY   B CA     1 
ATOM   1237 C  C      . GLY   A  1 77  ? 93.731  -12.619 -3.177  1.00 40.47  ?  6875 GLY   B C      1 
ATOM   1238 O  O      . GLY   A  1 77  ? 93.682  -11.852 -4.146  1.00 44.35  ?  6875 GLY   B O      1 
ATOM   1239 H  H      A GLY   A  1 77  ? 93.576  -13.257 -0.364  0.61 55.26  ?  6875 GLY   B H      1 
ATOM   1240 H  H      B GLY   A  1 77  ? 93.576  -13.257 -0.364  0.39 55.26  ?  6875 GLY   B H      1 
ATOM   1241 H  HA2    . GLY   A  1 77  ? 93.407  -11.463 -1.544  1.00 51.48  ?  6875 GLY   B HA2    1 
ATOM   1242 H  HA3    . GLY   A  1 77  ? 94.935  -11.572 -1.927  1.00 51.48  ?  6875 GLY   B HA3    1 
ATOM   1243 N  N      . VAL   A  1 78  ? 93.452  -13.915 -3.276  1.00 45.38  ?  6876 VAL   B N      1 
ATOM   1244 C  CA     . VAL   A  1 78  ? 93.146  -14.574 -4.530  1.00 41.97  ?  6876 VAL   B CA     1 
ATOM   1245 C  C      . VAL   A  1 78  ? 91.814  -15.300 -4.370  1.00 43.33  ?  6876 VAL   B C      1 
ATOM   1246 O  O      . VAL   A  1 78  ? 91.192  -15.264 -3.310  1.00 41.50  ?  6876 VAL   B O      1 
ATOM   1247 C  CB     . VAL   A  1 78  ? 94.273  -15.529 -4.968  1.00 41.47  ?  6876 VAL   B CB     1 
ATOM   1248 C  CG1    . VAL   A  1 78  ? 95.487  -14.716 -5.407  1.00 43.32  ?  6876 VAL   B CG1    1 
ATOM   1249 C  CG2    . VAL   A  1 78  ? 94.636  -16.470 -3.839  1.00 43.84  ?  6876 VAL   B CG2    1 
ATOM   1250 H  H      . VAL   A  1 78  ? 93.436  -14.449 -2.602  1.00 54.98  ?  6876 VAL   B H      1 
ATOM   1251 H  HA     . VAL   A  1 78  ? 93.037  -13.911 -5.229  1.00 50.89  ?  6876 VAL   B HA     1 
ATOM   1252 H  HB     . VAL   A  1 78  ? 93.972  -16.068 -5.716  1.00 50.29  ?  6876 VAL   B HB     1 
ATOM   1253 H  HG11   . VAL   A  1 78  ? 96.244  -15.312 -5.515  1.00 52.50  ?  6876 VAL   B HG11   1 
ATOM   1254 H  HG12   . VAL   A  1 78  ? 95.287  -14.279 -6.249  1.00 52.50  ?  6876 VAL   B HG12   1 
ATOM   1255 H  HG13   . VAL   A  1 78  ? 95.684  -14.051 -4.728  1.00 52.50  ?  6876 VAL   B HG13   1 
ATOM   1256 H  HG21   . VAL   A  1 78  ? 95.291  -17.110 -4.159  1.00 53.13  ?  6876 VAL   B HG21   1 
ATOM   1257 H  HG22   . VAL   A  1 78  ? 95.007  -15.955 -3.105  1.00 53.13  ?  6876 VAL   B HG22   1 
ATOM   1258 H  HG23   . VAL   A  1 78  ? 93.837  -16.935 -3.545  1.00 53.13  ?  6876 VAL   B HG23   1 
ATOM   1259 N  N      . ALA   A  1 79  ? 91.359  -15.931 -5.446  1.00 44.43  ?  6877 ALA   B N      1 
ATOM   1260 C  CA     . ALA   A  1 79  ? 90.032  -16.542 -5.499  1.00 39.46  ?  6877 ALA   B CA     1 
ATOM   1261 C  C      . ALA   A  1 79  ? 90.161  -17.984 -5.967  1.00 41.51  ?  6877 ALA   B C      1 
ATOM   1262 O  O      . ALA   A  1 79  ? 89.797  -18.320 -7.101  1.00 42.36  ?  6877 ALA   B O      1 
ATOM   1263 C  CB     . ALA   A  1 79  ? 89.106  -15.739 -6.411  1.00 35.61  ?  6877 ALA   B CB     1 
ATOM   1264 H  H      . ALA   A  1 79  ? 91.808  -16.020 -6.174  1.00 53.84  ?  6877 ALA   B H      1 
ATOM   1265 H  HA     . ALA   A  1 79  ? 89.648  -16.556 -4.608  1.00 47.88  ?  6877 ALA   B HA     1 
ATOM   1266 H  HB1    . ALA   A  1 79  ? 88.228  -16.151 -6.411  1.00 43.26  ?  6877 ALA   B HB1    1 
ATOM   1267 H  HB2    . ALA   A  1 79  ? 89.045  -14.830 -6.078  1.00 43.26  ?  6877 ALA   B HB2    1 
ATOM   1268 H  HB3    . ALA   A  1 79  ? 89.471  -15.739 -7.310  1.00 43.26  ?  6877 ALA   B HB3    1 
ATOM   1269 N  N      . PRO   A  1 80  ? 90.672  -18.870 -5.106  1.00 37.93  ?  6878 PRO   B N      1 
ATOM   1270 C  CA     . PRO   A  1 80  ? 90.832  -20.272 -5.525  1.00 39.48  ?  6878 PRO   B CA     1 
ATOM   1271 C  C      . PRO   A  1 80  ? 89.539  -20.903 -6.000  1.00 40.79  ?  6878 PRO   B C      1 
ATOM   1272 O  O      . PRO   A  1 80  ? 89.528  -21.599 -7.020  1.00 36.70  ?  6878 PRO   B O      1 
ATOM   1273 C  CB     . PRO   A  1 80  ? 91.352  -20.974 -4.259  1.00 43.32  ?  6878 PRO   B CB     1 
ATOM   1274 C  CG     . PRO   A  1 80  ? 91.909  -19.843 -3.389  1.00 36.50  ?  6878 PRO   B CG     1 
ATOM   1275 C  CD     . PRO   A  1 80  ? 91.018  -18.651 -3.691  1.00 40.75  ?  6878 PRO   B CD     1 
ATOM   1276 H  HA     . PRO   A  1 80  ? 91.504  -20.321 -6.223  1.00 47.89  ?  6878 PRO   B HA     1 
ATOM   1277 H  HB2    . PRO   A  1 80  ? 90.624  -21.431 -3.811  1.00 52.51  ?  6878 PRO   B HB2    1 
ATOM   1278 H  HB3    . PRO   A  1 80  ? 92.048  -21.608 -4.493  1.00 52.51  ?  6878 PRO   B HB3    1 
ATOM   1279 H  HG2    . PRO   A  1 80  ? 91.856  -20.088 -2.452  1.00 44.32  ?  6878 PRO   B HG2    1 
ATOM   1280 H  HG3    . PRO   A  1 80  ? 92.830  -19.660 -3.632  1.00 44.32  ?  6878 PRO   B HG3    1 
ATOM   1281 H  HD2    . PRO   A  1 80  ? 90.225  -18.657 -3.132  1.00 49.42  ?  6878 PRO   B HD2    1 
ATOM   1282 H  HD3    . PRO   A  1 80  ? 91.500  -17.817 -3.575  1.00 49.42  ?  6878 PRO   B HD3    1 
ATOM   1283 N  N      . GLY   A  1 81  ? 88.446  -20.679 -5.271  1.00 44.18  ?  6879 GLY   B N      1 
ATOM   1284 C  CA     . GLY   A  1 81  ? 87.179  -21.273 -5.651  1.00 37.80  ?  6879 GLY   B CA     1 
ATOM   1285 C  C      . GLY   A  1 81  ? 86.676  -20.785 -6.995  1.00 40.21  ?  6879 GLY   B C      1 
ATOM   1286 O  O      . GLY   A  1 81  ? 86.151  -21.570 -7.795  1.00 43.61  ?  6879 GLY   B O      1 
ATOM   1287 H  H      . GLY   A  1 81  ? 88.416  -20.193 -4.562  1.00 53.54  ?  6879 GLY   B H      1 
ATOM   1288 H  HA2    . GLY   A  1 81  ? 87.280  -22.237 -5.696  1.00 45.89  ?  6879 GLY   B HA2    1 
ATOM   1289 H  HA3    . GLY   A  1 81  ? 86.512  -21.057 -4.980  1.00 45.89  ?  6879 GLY   B HA3    1 
ATOM   1290 N  N      . THR   A  1 82  ? 86.800  -19.480 -7.252  1.00 42.05  ?  6880 THR   B N      1 
ATOM   1291 C  CA     . THR   A  1 82  ? 86.380  -18.950 -8.541  1.00 43.20  ?  6880 THR   B CA     1 
ATOM   1292 C  C      . THR   A  1 82  ? 87.117  -19.640 -9.677  1.00 37.96  ?  6880 THR   B C      1 
ATOM   1293 O  O      . THR   A  1 82  ? 86.521  -19.951 -10.713 1.00 40.78  ?  6880 THR   B O      1 
ATOM   1294 C  CB     . THR   A  1 82  ? 86.590  -17.443 -8.569  1.00 33.10  ?  6880 THR   B CB     1 
ATOM   1295 O  OG1    . THR   A  1 82  ? 85.630  -16.840 -7.695  1.00 39.13  ?  6880 THR   B OG1    1 
ATOM   1296 C  CG2    . THR   A  1 82  ? 86.391  -16.897 -9.963  1.00 34.96  ?  6880 THR   B CG2    1 
ATOM   1297 H  H      . THR   A  1 82  ? 87.117  -18.896 -6.706  1.00 50.98  ?  6880 THR   B H      1 
ATOM   1298 H  HA     . THR   A  1 82  ? 85.433  -19.114 -8.668  1.00 52.37  ?  6880 THR   B HA     1 
ATOM   1299 H  HB     . THR   A  1 82  ? 87.494  -17.231 -8.288  1.00 40.24  ?  6880 THR   B HB     1 
ATOM   1300 H  HG1    . THR   A  1 82  ? 85.768  -16.013 -7.644  1.00 47.48  ?  6880 THR   B HG1    1 
ATOM   1301 H  HG21   . THR   A  1 82  ? 86.312  -15.930 -9.933  1.00 42.48  ?  6880 THR   B HG21   1 
ATOM   1302 H  HG22   . THR   A  1 82  ? 87.146  -17.133 -10.524 1.00 42.48  ?  6880 THR   B HG22   1 
ATOM   1303 H  HG23   . THR   A  1 82  ? 85.583  -17.266 -10.352 1.00 42.48  ?  6880 THR   B HG23   1 
ATOM   1304 N  N      . ALA   A  1 83  ? 88.396  -19.939 -9.478  1.00 37.92  ?  6881 ALA   B N      1 
ATOM   1305 C  CA     . ALA   A  1 83  ? 89.175  -20.581 -10.526 1.00 40.88  ?  6881 ALA   B CA     1 
ATOM   1306 C  C      . ALA   A  1 83  ? 88.679  -21.992 -10.810 1.00 41.37  ?  6881 ALA   B C      1 
ATOM   1307 O  O      . ALA   A  1 83  ? 88.628  -22.417 -11.974 1.00 42.09  ?  6881 ALA   B O      1 
ATOM   1308 C  CB     . ALA   A  1 83  ? 90.648  -20.605 -10.132 1.00 39.71  ?  6881 ALA   B CB     1 
ATOM   1309 H  H      . ALA   A  1 83  ? 88.832  -19.783 -8.753  1.00 46.03  ?  6881 ALA   B H      1 
ATOM   1310 H  HA     . ALA   A  1 83  ? 89.083  -20.064 -11.342 1.00 49.57  ?  6881 ALA   B HA     1 
ATOM   1311 H  HB1    . ALA   A  1 83  ? 91.154  -21.050 -10.830 1.00 48.17  ?  6881 ALA   B HB1    1 
ATOM   1312 H  HB2    . ALA   A  1 83  ? 90.962  -19.693 -10.027 1.00 48.17  ?  6881 ALA   B HB2    1 
ATOM   1313 H  HB3    . ALA   A  1 83  ? 90.743  -21.086 -9.296  1.00 48.17  ?  6881 ALA   B HB3    1 
ATOM   1314 N  N      . VAL   A  1 84  ? 88.337  -22.749 -9.762  1.00 38.52  ?  6882 VAL   B N      1 
ATOM   1315 C  CA     . VAL   A  1 84  ? 87.756  -24.069 -9.986  1.00 44.14  ?  6882 VAL   B CA     1 
ATOM   1316 C  C      . VAL   A  1 84  ? 86.414  -23.942 -10.695 1.00 38.83  ?  6882 VAL   B C      1 
ATOM   1317 O  O      . VAL   A  1 84  ? 86.104  -24.715 -11.607 1.00 40.59  ?  6882 VAL   B O      1 
ATOM   1318 C  CB     . VAL   A  1 84  ? 87.613  -24.841 -8.662  1.00 38.61  ?  6882 VAL   B CB     1 
ATOM   1319 C  CG1    . VAL   A  1 84  ? 86.949  -26.201 -8.916  1.00 38.03  ?  6882 VAL   B CG1    1 
ATOM   1320 C  CG2    . VAL   A  1 84  ? 88.967  -25.050 -8.023  1.00 38.78  ?  6882 VAL   B CG2    1 
ATOM   1321 H  H      . VAL   A  1 84  ? 88.429  -22.525 -8.937  1.00 46.74  ?  6882 VAL   B H      1 
ATOM   1322 H  HA     . VAL   A  1 84  ? 88.360  -24.569 -10.556 1.00 53.49  ?  6882 VAL   B HA     1 
ATOM   1323 H  HB     . VAL   A  1 84  ? 87.060  -24.324 -8.056  1.00 46.85  ?  6882 VAL   B HB     1 
ATOM   1324 H  HG11   . VAL   A  1 84  ? 87.078  -26.766 -8.138  1.00 46.16  ?  6882 VAL   B HG11   1 
ATOM   1325 H  HG12   . VAL   A  1 84  ? 86.001  -26.065 -9.073  1.00 46.16  ?  6882 VAL   B HG12   1 
ATOM   1326 H  HG13   . VAL   A  1 84  ? 87.357  -26.612 -9.694  1.00 46.16  ?  6882 VAL   B HG13   1 
ATOM   1327 H  HG21   . VAL   A  1 84  ? 88.852  -25.534 -7.190  1.00 47.06  ?  6882 VAL   B HG21   1 
ATOM   1328 H  HG22   . VAL   A  1 84  ? 89.527  -25.562 -8.628  1.00 47.06  ?  6882 VAL   B HG22   1 
ATOM   1329 H  HG23   . VAL   A  1 84  ? 89.372  -24.185 -7.850  1.00 47.06  ?  6882 VAL   B HG23   1 
ATOM   1330 N  N      . LEU   A  1 85  ? 85.590  -22.976 -10.277 1.00 38.51  ?  6883 LEU   B N      1 
ATOM   1331 C  CA     . LEU   A  1 85  ? 84.288  -22.793 -10.910 1.00 37.19  ?  6883 LEU   B CA     1 
ATOM   1332 C  C      . LEU   A  1 85  ? 84.435  -22.528 -12.404 1.00 37.33  ?  6883 LEU   B C      1 
ATOM   1333 O  O      . LEU   A  1 85  ? 83.670  -23.065 -13.213 1.00 37.63  ?  6883 LEU   B O      1 
ATOM   1334 C  CB     . LEU   A  1 85  ? 83.528  -21.650 -10.233 1.00 36.53  ?  6883 LEU   B CB     1 
ATOM   1335 C  CG     . LEU   A  1 85  ? 83.055  -21.995 -8.826  1.00 36.30  ?  6883 LEU   B CG     1 
ATOM   1336 C  CD1    . LEU   A  1 85  ? 82.397  -20.783 -8.193  1.00 35.02  ?  6883 LEU   B CD1    1 
ATOM   1337 C  CD2    . LEU   A  1 85  ? 82.096  -23.159 -8.843  1.00 36.76  ?  6883 LEU   B CD2    1 
ATOM   1338 H  H      . LEU   A  1 85  ? 85.760  -22.424 -9.640  1.00 46.73  ?  6883 LEU   B H      1 
ATOM   1339 H  HA     . LEU   A  1 85  ? 83.770  -23.605 -10.797 1.00 45.15  ?  6883 LEU   B HA     1 
ATOM   1340 H  HB2    . LEU   A  1 85  ? 84.112  -20.878 -10.172 1.00 44.36  ?  6883 LEU   B HB2    1 
ATOM   1341 H  HB3    . LEU   A  1 85  ? 82.747  -21.434 -10.767 1.00 44.36  ?  6883 LEU   B HB3    1 
ATOM   1342 H  HG     . LEU   A  1 85  ? 83.822  -22.255 -8.291  1.00 44.08  ?  6883 LEU   B HG     1 
ATOM   1343 H  HD11   . LEU   A  1 85  ? 82.161  -20.995 -7.276  1.00 42.54  ?  6883 LEU   B HD11   1 
ATOM   1344 H  HD12   . LEU   A  1 85  ? 83.021  -20.040 -8.211  1.00 42.54  ?  6883 LEU   B HD12   1 
ATOM   1345 H  HD13   . LEU   A  1 85  ? 81.600  -20.557 -8.696  1.00 42.54  ?  6883 LEU   B HD13   1 
ATOM   1346 H  HD21   . LEU   A  1 85  ? 81.613  -23.183 -8.002  1.00 44.64  ?  6883 LEU   B HD21   1 
ATOM   1347 H  HD22   . LEU   A  1 85  ? 81.474  -23.045 -9.579  1.00 44.64  ?  6883 LEU   B HD22   1 
ATOM   1348 H  HD23   . LEU   A  1 85  ? 82.599  -23.980 -8.959  1.00 44.64  ?  6883 LEU   B HD23   1 
ATOM   1349 N  N      . ARG   A  1 86  ? 85.415  -21.707 -12.788 1.00 40.07  ?  6884 ARG   B N      1 
ATOM   1350 C  CA     . ARG   A  1 86  ? 85.581  -21.351 -14.192 1.00 45.21  ?  6884 ARG   B CA     1 
ATOM   1351 C  C      . ARG   A  1 86  ? 86.154  -22.513 -14.993 1.00 39.29  ?  6884 ARG   B C      1 
ATOM   1352 O  O      . ARG   A  1 86  ? 85.804  -22.701 -16.163 1.00 44.67  ?  6884 ARG   B O      1 
ATOM   1353 C  CB     . ARG   A  1 86  ? 86.479  -20.119 -14.306 1.00 38.13  ?  6884 ARG   B CB     1 
ATOM   1354 C  CG     . ARG   A  1 86  ? 86.501  -19.440 -15.647 1.00 44.79  ?  6884 ARG   B CG     1 
ATOM   1355 C  CD     . ARG   A  1 86  ? 87.341  -18.167 -15.541 1.00 38.46  ?  6884 ARG   B CD     1 
ATOM   1356 N  NE     . ARG   A  1 86  ? 87.297  -17.299 -16.711 1.00 45.81  ?  6884 ARG   B NE     1 
ATOM   1357 C  CZ     . ARG   A  1 86  ? 86.311  -16.452 -16.982 1.00 39.33  ?  6884 ARG   B CZ     1 
ATOM   1358 N  NH1    . ARG   A  1 86  ? 85.171  -16.488 -16.321 1.00 40.75  ?  6884 ARG   B NH1    1 
ATOM   1359 N  NH2    . ARG   A  1 86  ? 86.473  -15.545 -17.944 1.00 44.43  ?  6884 ARG   B NH2    1 
ATOM   1360 H  H      . ARG   A  1 86  ? 85.990  -21.347 -12.259 1.00 48.60  ?  6884 ARG   B H      1 
ATOM   1361 H  HA     . ARG   A  1 86  ? 84.714  -21.132 -14.570 1.00 54.78  ?  6884 ARG   B HA     1 
ATOM   1362 H  HB2    . ARG   A  1 86  ? 86.177  -19.463 -13.658 1.00 46.28  ?  6884 ARG   B HB2    1 
ATOM   1363 H  HB3    . ARG   A  1 86  ? 87.389  -20.388 -14.106 1.00 46.28  ?  6884 ARG   B HB3    1 
ATOM   1364 H  HG2    . ARG   A  1 86  ? 86.899  -20.026 -16.310 1.00 54.27  ?  6884 ARG   B HG2    1 
ATOM   1365 H  HG3    . ARG   A  1 86  ? 85.599  -19.202 -15.914 1.00 54.27  ?  6884 ARG   B HG3    1 
ATOM   1366 H  HD2    . ARG   A  1 86  ? 87.023  -17.651 -14.784 1.00 46.67  ?  6884 ARG   B HD2    1 
ATOM   1367 H  HD3    . ARG   A  1 86  ? 88.267  -18.421 -15.403 1.00 46.67  ?  6884 ARG   B HD3    1 
ATOM   1368 H  HE     . ARG   A  1 86  ? 87.955  -17.338 -17.263 1.00 55.50  ?  6884 ARG   B HE     1 
ATOM   1369 H  HH11   . ARG   A  1 86  ? 85.053  -17.070 -15.698 1.00 49.42  ?  6884 ARG   B HH11   1 
ATOM   1370 H  HH12   . ARG   A  1 86  ? 84.544  -15.931 -16.512 1.00 49.42  ?  6884 ARG   B HH12   1 
ATOM   1371 H  HH21   . ARG   A  1 86  ? 87.212  -15.511 -18.383 1.00 53.84  ?  6884 ARG   B HH21   1 
ATOM   1372 H  HH22   . ARG   A  1 86  ? 85.840  -14.993 -18.126 1.00 53.84  ?  6884 ARG   B HH22   1 
ATOM   1373 N  N      . GLN   A  1 87  ? 87.048  -23.283 -14.390 1.00 40.11  ?  6885 GLN   B N      1 
ATOM   1374 C  CA     . GLN   A  1 87  ? 87.487  -24.528 -15.004 1.00 41.70  ?  6885 GLN   B CA     1 
ATOM   1375 C  C      . GLN   A  1 87  ? 86.314  -25.468 -15.258 1.00 41.95  ?  6885 GLN   B C      1 
ATOM   1376 O  O      . GLN   A  1 87  ? 86.149  -25.998 -16.364 1.00 46.48  ?  6885 GLN   B O      1 
ATOM   1377 C  CB     . GLN   A  1 87  ? 88.517  -25.167 -14.083 1.00 34.67  ?  6885 GLN   B CB     1 
ATOM   1378 C  CG     . GLN   A  1 87  ? 89.010  -26.535 -14.476 1.00 38.56  ?  6885 GLN   B CG     1 
ATOM   1379 C  CD     . GLN   A  1 87  ? 89.830  -27.197 -13.371 1.00 36.99  ?  6885 GLN   B CD     1 
ATOM   1380 O  OE1    . GLN   A  1 87  ? 90.417  -28.270 -13.570 1.00 41.85  ?  6885 GLN   B OE1    1 
ATOM   1381 N  NE2    . GLN   A  1 87  ? 89.890  -26.555 -12.209 1.00 45.50  ?  6885 GLN   B NE2    1 
ATOM   1382 H  H      . GLN   A  1 87  ? 87.414  -23.110 -13.631 1.00 48.65  ?  6885 GLN   B H      1 
ATOM   1383 H  HA     . GLN   A  1 87  ? 87.894  -24.351 -15.866 1.00 50.56  ?  6885 GLN   B HA     1 
ATOM   1384 H  HB2    . GLN   A  1 87  ? 89.292  -24.584 -14.048 1.00 42.12  ?  6885 GLN   B HB2    1 
ATOM   1385 H  HB3    . GLN   A  1 87  ? 88.123  -25.249 -13.201 1.00 42.12  ?  6885 GLN   B HB3    1 
ATOM   1386 H  HG2    . GLN   A  1 87  ? 88.248  -27.104 -14.668 1.00 46.79  ?  6885 GLN   B HG2    1 
ATOM   1387 H  HG3    . GLN   A  1 87  ? 89.572  -26.456 -15.262 1.00 46.79  ?  6885 GLN   B HG3    1 
ATOM   1388 H  HE21   . GLN   A  1 87  ? 89.479  -25.806 -12.110 1.00 55.12  ?  6885 GLN   B HE21   1 
ATOM   1389 H  HE22   . GLN   A  1 87  ? 90.339  -26.888 -11.556 1.00 55.12  ?  6885 GLN   B HE22   1 
ATOM   1390 N  N      . TRP   A  1 88  ? 85.466  -25.644 -14.246 1.00 41.68  ?  6886 TRP   B N      1 
ATOM   1391 C  CA     . TRP   A  1 88  ? 84.339  -26.565 -14.326 1.00 40.16  ?  6886 TRP   B CA     1 
ATOM   1392 C  C      . TRP   A  1 88  ? 83.304  -26.094 -15.335 1.00 32.39  ?  6886 TRP   B C      1 
ATOM   1393 O  O      . TRP   A  1 88  ? 82.865  -26.866 -16.192 1.00 39.71  ?  6886 TRP   B O      1 
ATOM   1394 C  CB     . TRP   A  1 88  ? 83.732  -26.685 -12.937 1.00 38.02  ?  6886 TRP   B CB     1 
ATOM   1395 C  CG     . TRP   A  1 88  ? 82.527  -27.508 -12.775 1.00 39.21  ?  6886 TRP   B CG     1 
ATOM   1396 C  CD1    . TRP   A  1 88  ? 82.386  -28.828 -13.065 1.00 34.44  ?  6886 TRP   B CD1    1 
ATOM   1397 C  CD2    . TRP   A  1 88  ? 81.272  -27.072 -12.245 1.00 38.29  ?  6886 TRP   B CD2    1 
ATOM   1398 N  NE1    . TRP   A  1 88  ? 81.118  -29.245 -12.748 1.00 40.51  ?  6886 TRP   B NE1    1 
ATOM   1399 C  CE2    . TRP   A  1 88  ? 80.415  -28.187 -12.235 1.00 39.01  ?  6886 TRP   B CE2    1 
ATOM   1400 C  CE3    . TRP   A  1 88  ? 80.793  -25.845 -11.771 1.00 40.46  ?  6886 TRP   B CE3    1 
ATOM   1401 C  CZ2    . TRP   A  1 88  ? 79.099  -28.120 -11.781 1.00 40.39  ?  6886 TRP   B CZ2    1 
ATOM   1402 C  CZ3    . TRP   A  1 88  ? 79.482  -25.778 -11.317 1.00 38.70  ?  6886 TRP   B CZ3    1 
ATOM   1403 C  CH2    . TRP   A  1 88  ? 78.650  -26.909 -11.334 1.00 39.27  ?  6886 TRP   B CH2    1 
ATOM   1404 H  H      . TRP   A  1 88  ? 85.522  -25.236 -13.491 1.00 50.54  ?  6886 TRP   B H      1 
ATOM   1405 H  HA     . TRP   A  1 88  ? 84.644  -27.437 -14.621 1.00 48.72  ?  6886 TRP   B HA     1 
ATOM   1406 H  HB2    . TRP   A  1 88  ? 84.407  -27.064 -12.352 1.00 46.15  ?  6886 TRP   B HB2    1 
ATOM   1407 H  HB3    . TRP   A  1 88  ? 83.499  -25.792 -12.639 1.00 46.15  ?  6886 TRP   B HB3    1 
ATOM   1408 H  HD1    . TRP   A  1 88  ? 83.051  -29.369 -13.425 1.00 41.85  ?  6886 TRP   B HD1    1 
ATOM   1409 H  HE1    . TRP   A  1 88  ? 80.814  -30.042 -12.854 1.00 49.13  ?  6886 TRP   B HE1    1 
ATOM   1410 H  HE3    . TRP   A  1 88  ? 81.339  -25.092 -11.760 1.00 49.08  ?  6886 TRP   B HE3    1 
ATOM   1411 H  HZ2    . TRP   A  1 88  ? 78.548  -28.869 -11.783 1.00 48.99  ?  6886 TRP   B HZ2    1 
ATOM   1412 H  HZ3    . TRP   A  1 88  ? 79.150  -24.971 -10.996 1.00 46.96  ?  6886 TRP   B HZ3    1 
ATOM   1413 H  HH2    . TRP   A  1 88  ? 77.773  -26.832 -11.034 1.00 47.65  ?  6886 TRP   B HH2    1 
ATOM   1414 N  N      . LEU   A  1 89  ? 82.903  -24.831 -15.239 1.00 43.84  ?  6887 LEU   B N      1 
ATOM   1415 C  CA     . LEU   A  1 89  ? 81.846  -24.302 -16.075 1.00 41.87  ?  6887 LEU   B CA     1 
ATOM   1416 C  C      . LEU   A  1 89  ? 82.279  -24.283 -17.534 1.00 39.20  ?  6887 LEU   B C      1 
ATOM   1417 O  O      . LEU   A  1 89  ? 83.476  -24.157 -17.844 1.00 40.93  ?  6887 LEU   B O      1 
ATOM   1418 C  CB     . LEU   A  1 89  ? 81.461  -22.904 -15.626 1.00 38.85  ?  6887 LEU   B CB     1 
ATOM   1419 C  CG     . LEU   A  1 89  ? 80.893  -22.861 -14.212 1.00 42.41  ?  6887 LEU   B CG     1 
ATOM   1420 C  CD1    . LEU   A  1 89  ? 80.931  -21.434 -13.700 1.00 37.50  ?  6887 LEU   B CD1    1 
ATOM   1421 C  CD2    . LEU   A  1 89  ? 79.460  -23.390 -14.224 1.00 41.01  ?  6887 LEU   B CD2    1 
ATOM   1422 H  H      . LEU   A  1 89  ? 83.233  -24.256 -14.691 1.00 53.12  ?  6887 LEU   B H      1 
ATOM   1423 H  HA     . LEU   A  1 89  ? 81.064  -24.871 -16.000 1.00 50.77  ?  6887 LEU   B HA     1 
ATOM   1424 H  HB2    . LEU   A  1 89  ? 82.250  -22.340 -15.648 1.00 47.15  ?  6887 LEU   B HB2    1 
ATOM   1425 H  HB3    . LEU   A  1 89  ? 80.787  -22.556 -16.229 1.00 47.15  ?  6887 LEU   B HB3    1 
ATOM   1426 H  HG     . LEU   A  1 89  ? 81.419  -23.417 -13.616 1.00 51.41  ?  6887 LEU   B HG     1 
ATOM   1427 H  HD11   . LEU   A  1 89  ? 80.533  -21.405 -12.816 1.00 45.52  ?  6887 LEU   B HD11   1 
ATOM   1428 H  HD12   . LEU   A  1 89  ? 81.854  -21.139 -13.657 1.00 45.52  ?  6887 LEU   B HD12   1 
ATOM   1429 H  HD13   . LEU   A  1 89  ? 80.430  -20.867 -14.308 1.00 45.52  ?  6887 LEU   B HD13   1 
ATOM   1430 H  HD21   . LEU   A  1 89  ? 79.088  -23.315 -13.331 1.00 49.74  ?  6887 LEU   B HD21   1 
ATOM   1431 H  HD22   . LEU   A  1 89  ? 78.934  -22.863 -14.846 1.00 49.74  ?  6887 LEU   B HD22   1 
ATOM   1432 H  HD23   . LEU   A  1 89  ? 79.468  -24.319 -14.502 1.00 49.74  ?  6887 LEU   B HD23   1 
ATOM   1433 N  N      . PRO   A  1 90  ? 81.331  -24.423 -18.448 1.00 38.20  ?  6888 PRO   B N      1 
ATOM   1434 C  CA     . PRO   A  1 90  ? 81.670  -24.311 -19.866 1.00 47.03  ?  6888 PRO   B CA     1 
ATOM   1435 C  C      . PRO   A  1 90  ? 82.375  -22.994 -20.149 1.00 48.13  ?  6888 PRO   B C      1 
ATOM   1436 O  O      . PRO   A  1 90  ? 82.091  -21.968 -19.523 1.00 45.89  ?  6888 PRO   B O      1 
ATOM   1437 C  CB     . PRO   A  1 90  ? 80.313  -24.388 -20.571 1.00 46.28  ?  6888 PRO   B CB     1 
ATOM   1438 C  CG     . PRO   A  1 90  ? 79.363  -24.970 -19.563 1.00 39.61  ?  6888 PRO   B CG     1 
ATOM   1439 C  CD     . PRO   A  1 90  ? 79.888  -24.603 -18.218 1.00 40.75  ?  6888 PRO   B CD     1 
ATOM   1440 H  HA     . PRO   A  1 90  ? 82.224  -25.054 -20.151 1.00 56.96  ?  6888 PRO   B HA     1 
ATOM   1441 H  HB2    . PRO   A  1 90  ? 80.031  -23.499 -20.837 1.00 56.06  ?  6888 PRO   B HB2    1 
ATOM   1442 H  HB3    . PRO   A  1 90  ? 80.382  -24.961 -21.351 1.00 56.06  ?  6888 PRO   B HB3    1 
ATOM   1443 H  HG2    . PRO   A  1 90  ? 78.478  -24.595 -19.697 1.00 48.05  ?  6888 PRO   B HG2    1 
ATOM   1444 H  HG3    . PRO   A  1 90  ? 79.333  -25.935 -19.665 1.00 48.05  ?  6888 PRO   B HG3    1 
ATOM   1445 H  HD2    . PRO   A  1 90  ? 79.484  -23.779 -17.904 1.00 49.43  ?  6888 PRO   B HD2    1 
ATOM   1446 H  HD3    . PRO   A  1 90  ? 79.727  -25.315 -17.579 1.00 49.43  ?  6888 PRO   B HD3    1 
ATOM   1447 N  N      . THR   A  1 91  ? 83.311  -23.040 -21.090 1.00 43.52  ?  6889 THR   B N      1 
ATOM   1448 C  CA     . THR   A  1 91  ? 83.988  -21.834 -21.506 1.00 47.76  ?  6889 THR   B CA     1 
ATOM   1449 C  C      . THR   A  1 91  ? 82.975  -20.831 -22.033 1.00 44.16  ?  6889 THR   B C      1 
ATOM   1450 O  O      . THR   A  1 91  ? 81.994  -21.194 -22.686 1.00 45.24  ?  6889 THR   B O      1 
ATOM   1451 C  CB     . THR   A  1 91  ? 85.040  -22.158 -22.562 1.00 45.89  ?  6889 THR   B CB     1 
ATOM   1452 O  OG1    . THR   A  1 91  ? 85.974  -23.081 -22.002 1.00 45.11  ?  6889 THR   B OG1    1 
ATOM   1453 C  CG2    . THR   A  1 91  ? 85.761  -20.908 -22.983 1.00 51.59  ?  6889 THR   B CG2    1 
ATOM   1454 H  H      . THR   A  1 91  ? 83.565  -23.753 -21.497 1.00 52.74  ?  6889 THR   B H      1 
ATOM   1455 H  HA     . THR   A  1 91  ? 84.450  -21.433 -20.754 1.00 57.83  ?  6889 THR   B HA     1 
ATOM   1456 H  HB     . THR   A  1 91  ? 84.621  -22.543 -23.348 1.00 55.60  ?  6889 THR   B HB     1 
ATOM   1457 H  HG1    . THR   A  1 91  ? 86.550  -23.291 -22.577 1.00 54.65  ?  6889 THR   B HG1    1 
ATOM   1458 H  HG21   . THR   A  1 91  ? 86.558  -21.139 -23.486 1.00 62.43  ?  6889 THR   B HG21   1 
ATOM   1459 H  HG22   . THR   A  1 91  ? 85.184  -20.364 -23.540 1.00 62.43  ?  6889 THR   B HG22   1 
ATOM   1460 H  HG23   . THR   A  1 91  ? 86.020  -20.395 -22.201 1.00 62.43  ?  6889 THR   B HG23   1 
ATOM   1461 N  N      . GLY   A  1 92  ? 83.199  -19.561 -21.710 1.00 45.87  ?  6890 GLY   B N      1 
ATOM   1462 C  CA     . GLY   A  1 92  ? 82.254  -18.522 -22.018 1.00 46.33  ?  6890 GLY   B CA     1 
ATOM   1463 C  C      . GLY   A  1 92  ? 81.183  -18.303 -20.975 1.00 41.78  ?  6890 GLY   B C      1 
ATOM   1464 O  O      . GLY   A  1 92  ? 80.411  -17.342 -21.097 1.00 46.17  ?  6890 GLY   B O      1 
ATOM   1465 H  H      . GLY   A  1 92  ? 83.905  -19.283 -21.306 1.00 55.57  ?  6890 GLY   B H      1 
ATOM   1466 H  HA2    . GLY   A  1 92  ? 82.736  -17.687 -22.125 1.00 56.12  ?  6890 GLY   B HA2    1 
ATOM   1467 H  HA3    . GLY   A  1 92  ? 81.813  -18.742 -22.853 1.00 56.12  ?  6890 GLY   B HA3    1 
ATOM   1468 N  N      . THR   A  1 93  ? 81.096  -19.158 -19.963 1.00 46.81  ?  6891 THR   B N      1 
ATOM   1469 C  CA     . THR   A  1 93  ? 80.105  -18.949 -18.921 1.00 46.47  ?  6891 THR   B CA     1 
ATOM   1470 C  C      . THR   A  1 93  ? 80.389  -17.634 -18.206 1.00 35.58  ?  6891 THR   B C      1 
ATOM   1471 O  O      . THR   A  1 93  ? 81.518  -17.386 -17.773 1.00 44.17  ?  6891 THR   B O      1 
ATOM   1472 C  CB     . THR   A  1 93  ? 80.133  -20.099 -17.912 1.00 44.19  ?  6891 THR   B CB     1 
ATOM   1473 O  OG1    . THR   A  1 93  ? 79.825  -21.340 -18.551 1.00 43.66  ?  6891 THR   B OG1    1 
ATOM   1474 C  CG2    . THR   A  1 93  ? 79.102  -19.838 -16.804 1.00 45.38  ?  6891 THR   B CG2    1 
ATOM   1475 H  H      . THR   A  1 93  ? 81.591  -19.854 -19.860 1.00 56.70  ?  6891 THR   B H      1 
ATOM   1476 H  HA     . THR   A  1 93  ? 79.221  -18.919 -19.319 1.00 56.29  ?  6891 THR   B HA     1 
ATOM   1477 H  HB     . THR   A  1 93  ? 81.019  -20.162 -17.525 1.00 53.55  ?  6891 THR   B HB     1 
ATOM   1478 H  HG1    . THR   A  1 93  ? 80.456  -21.565 -19.058 1.00 52.91  ?  6891 THR   B HG1    1 
ATOM   1479 H  HG21   . THR   A  1 93  ? 78.941  -20.652 -16.302 1.00 54.98  ?  6891 THR   B HG21   1 
ATOM   1480 H  HG22   . THR   A  1 93  ? 79.432  -19.154 -16.199 1.00 54.98  ?  6891 THR   B HG22   1 
ATOM   1481 H  HG23   . THR   A  1 93  ? 78.266  -19.537 -17.193 1.00 54.98  ?  6891 THR   B HG23   1 
ATOM   1482 N  N      . LEU   A  1 94  ? 79.368  -16.788 -18.091 1.00 41.91  ?  6892 LEU   B N      1 
ATOM   1483 C  CA     . LEU   A  1 94  ? 79.498  -15.533 -17.353 1.00 42.45  ?  6892 LEU   B CA     1 
ATOM   1484 C  C      . LEU   A  1 94  ? 79.640  -15.833 -15.863 1.00 42.06  ?  6892 LEU   B C      1 
ATOM   1485 O  O      . LEU   A  1 94  ? 78.743  -16.436 -15.261 1.00 40.80  ?  6892 LEU   B O      1 
ATOM   1486 C  CB     . LEU   A  1 94  ? 78.269  -14.663 -17.592 1.00 45.25  ?  6892 LEU   B CB     1 
ATOM   1487 C  CG     . LEU   A  1 94  ? 77.996  -14.048 -18.962 1.00 59.89  ?  6892 LEU   B CG     1 
ATOM   1488 C  CD1    . LEU   A  1 94  ? 76.887  -12.973 -18.806 1.00 60.73  ?  6892 LEU   B CD1    1 
ATOM   1489 C  CD2    . LEU   A  1 94  ? 79.208  -13.424 -19.610 1.00 63.85  ?  6892 LEU   B CD2    1 
ATOM   1490 H  H      . LEU   A  1 94  ? 78.589  -16.917 -18.430 1.00 50.81  ?  6892 LEU   B H      1 
ATOM   1491 H  HA     . LEU   A  1 94  ? 80.285  -15.056 -17.658 1.00 51.46  ?  6892 LEU   B HA     1 
ATOM   1492 H  HB2    . LEU   A  1 94  ? 77.493  -15.208 -17.386 1.00 54.82  ?  6892 LEU   B HB2    1 
ATOM   1493 H  HB3    . LEU   A  1 94  ? 78.326  -13.919 -16.973 1.00 54.82  ?  6892 LEU   B HB3    1 
ATOM   1494 H  HG     . LEU   A  1 94  ? 77.720  -14.764 -19.554 1.00 72.40  ?  6892 LEU   B HG     1 
ATOM   1495 H  HD11   . LEU   A  1 94  ? 76.781  -12.505 -19.649 1.00 73.40  ?  6892 LEU   B HD11   1 
ATOM   1496 H  HD12   . LEU   A  1 94  ? 76.056  -13.410 -18.563 1.00 73.40  ?  6892 LEU   B HD12   1 
ATOM   1497 H  HD13   . LEU   A  1 94  ? 77.148  -12.348 -18.112 1.00 73.40  ?  6892 LEU   B HD13   1 
ATOM   1498 H  HD21   . LEU   A  1 94  ? 78.952  -13.060 -20.472 1.00 77.15  ?  6892 LEU   B HD21   1 
ATOM   1499 H  HD22   . LEU   A  1 94  ? 79.543  -12.716 -19.037 1.00 77.15  ?  6892 LEU   B HD22   1 
ATOM   1500 H  HD23   . LEU   A  1 94  ? 79.888  -14.105 -19.727 1.00 77.15  ?  6892 LEU   B HD23   1 
ATOM   1501 N  N      . LEU   A  1 95  ? 80.760  -15.422 -15.269 1.00 37.35  ?  6893 LEU   B N      1 
ATOM   1502 C  CA     . LEU   A  1 95  ? 81.041  -15.677 -13.863 1.00 41.31  ?  6893 LEU   B CA     1 
ATOM   1503 C  C      . LEU   A  1 95  ? 81.306  -14.360 -13.148 1.00 39.54  ?  6893 LEU   B C      1 
ATOM   1504 O  O      . LEU   A  1 95  ? 82.254  -13.641 -13.486 1.00 44.05  ?  6893 LEU   B O      1 
ATOM   1505 C  CB     . LEU   A  1 95  ? 82.242  -16.607 -13.710 1.00 38.41  ?  6893 LEU   B CB     1 
ATOM   1506 C  CG     . LEU   A  1 95  ? 82.572  -17.079 -12.297 1.00 31.04  ?  6893 LEU   B CG     1 
ATOM   1507 C  CD1    . LEU   A  1 95  ? 81.389  -17.734 -11.642 1.00 37.28  ?  6893 LEU   B CD1    1 
ATOM   1508 C  CD2    . LEU   A  1 95  ? 83.764  -18.022 -12.351 1.00 37.65  ?  6893 LEU   B CD2    1 
ATOM   1509 H  H      . LEU   A  1 95  ? 81.382  -14.986 -15.671 1.00 45.35  ?  6893 LEU   B H      1 
ATOM   1510 H  HA     . LEU   A  1 95  ? 80.263  -16.089 -13.457 1.00 50.09  ?  6893 LEU   B HA     1 
ATOM   1511 H  HB2    . LEU   A  1 95  ? 82.075  -17.401 -14.242 1.00 46.62  ?  6893 LEU   B HB2    1 
ATOM   1512 H  HB3    . LEU   A  1 95  ? 83.025  -16.142 -14.044 1.00 46.62  ?  6893 LEU   B HB3    1 
ATOM   1513 H  HG     . LEU   A  1 95  ? 82.801  -16.313 -11.747 1.00 37.77  ?  6893 LEU   B HG     1 
ATOM   1514 H  HD11   . LEU   A  1 95  ? 81.681  -18.168 -10.825 1.00 45.26  ?  6893 LEU   B HD11   1 
ATOM   1515 H  HD12   . LEU   A  1 95  ? 80.726  -17.056 -11.437 1.00 45.26  ?  6893 LEU   B HD12   1 
ATOM   1516 H  HD13   . LEU   A  1 95  ? 81.014  -18.390 -12.250 1.00 45.26  ?  6893 LEU   B HD13   1 
ATOM   1517 H  HD21   . LEU   A  1 95  ? 83.949  -18.349 -11.457 1.00 45.71  ?  6893 LEU   B HD21   1 
ATOM   1518 H  HD22   . LEU   A  1 95  ? 83.553  -18.765 -12.938 1.00 45.71  ?  6893 LEU   B HD22   1 
ATOM   1519 H  HD23   . LEU   A  1 95  ? 84.533  -17.539 -12.693 1.00 45.71  ?  6893 LEU   B HD23   1 
ATOM   1520 N  N      . VAL   A  1 96  ? 80.479  -14.055 -12.155 1.00 41.41  ?  6894 VAL   B N      1 
ATOM   1521 C  CA     . VAL   A  1 96  ? 80.660  -12.898 -11.286 1.00 39.57  ?  6894 VAL   B CA     1 
ATOM   1522 C  C      . VAL   A  1 96  ? 80.994  -13.408 -9.898  1.00 37.67  ?  6894 VAL   B C      1 
ATOM   1523 O  O      . VAL   A  1 96  ? 80.377  -14.370 -9.429  1.00 41.12  ?  6894 VAL   B O      1 
ATOM   1524 C  CB     . VAL   A  1 96  ? 79.395  -12.021 -11.240 1.00 38.19  ?  6894 VAL   B CB     1 
ATOM   1525 C  CG1    . VAL   A  1 96  ? 79.493  -11.001 -10.107 1.00 40.77  ?  6894 VAL   B CG1    1 
ATOM   1526 C  CG2    . VAL   A  1 96  ? 79.166  -11.337 -12.590 1.00 41.89  ?  6894 VAL   B CG2    1 
ATOM   1527 H  H      . VAL   A  1 96  ? 79.783  -14.520 -11.958 1.00 50.22  ?  6894 VAL   B H      1 
ATOM   1528 H  HA     . VAL   A  1 96  ? 81.394  -12.357 -11.618 1.00 48.00  ?  6894 VAL   B HA     1 
ATOM   1529 H  HB     . VAL   A  1 96  ? 78.624  -12.583 -11.063 1.00 46.35  ?  6894 VAL   B HB     1 
ATOM   1530 H  HG11   . VAL   A  1 96  ? 78.839  -10.300 -10.255 1.00 49.44  ?  6894 VAL   B HG11   1 
ATOM   1531 H  HG12   . VAL   A  1 96  ? 79.314  -11.448 -9.264  1.00 49.44  ?  6894 VAL   B HG12   1 
ATOM   1532 H  HG13   . VAL   A  1 96  ? 80.386  -10.624 -10.098 1.00 49.44  ?  6894 VAL   B HG13   1 
ATOM   1533 H  HG21   . VAL   A  1 96  ? 78.357  -10.804 -12.541 1.00 50.79  ?  6894 VAL   B HG21   1 
ATOM   1534 H  HG22   . VAL   A  1 96  ? 79.926  -10.768 -12.789 1.00 50.79  ?  6894 VAL   B HG22   1 
ATOM   1535 H  HG23   . VAL   A  1 96  ? 79.073  -12.016 -13.277 1.00 50.79  ?  6894 VAL   B HG23   1 
ATOM   1536 N  N      . ASP   A  1 97  ? 81.940  -12.761 -9.221  1.00 42.99  ?  6895 ASP   B N      1 
ATOM   1537 C  CA     . ASP   A  1 97  ? 82.180  -13.092 -7.824  1.00 44.77  ?  6895 ASP   B CA     1 
ATOM   1538 C  C      . ASP   A  1 97  ? 82.288  -11.823 -6.986  1.00 38.40  ?  6895 ASP   B C      1 
ATOM   1539 O  O      . ASP   A  1 97  ? 82.343  -10.698 -7.492  1.00 41.39  ?  6895 ASP   B O      1 
ATOM   1540 C  CB     . ASP   A  1 97  ? 83.416  -13.988 -7.638  1.00 38.23  ?  6895 ASP   B CB     1 
ATOM   1541 C  CG     . ASP   A  1 97  ? 84.719  -13.318 -8.026  1.00 36.38  ?  6895 ASP   B CG     1 
ATOM   1542 O  OD1    . ASP   A  1 97  ? 84.722  -12.146 -8.453  1.00 44.49  ?  6895 ASP   B OD1    1 
ATOM   1543 O  OD2    . ASP   A  1 97  ? 85.770  -13.983 -7.904  1.00 39.15  ?  6895 ASP   B OD2    1 
ATOM   1544 H  H      . ASP   A  1 97  ? 82.442  -12.142 -9.545  1.00 52.10  ?  6895 ASP   B H      1 
ATOM   1545 H  HA     . ASP   A  1 97  ? 81.414  -13.587 -7.496  1.00 54.24  ?  6895 ASP   B HA     1 
ATOM   1546 H  HB2    . ASP   A  1 97  ? 83.480  -14.242 -6.704  1.00 46.40  ?  6895 ASP   B HB2    1 
ATOM   1547 H  HB3    . ASP   A  1 97  ? 83.314  -14.779 -8.190  1.00 46.40  ?  6895 ASP   B HB3    1 
ATOM   1548 N  N      . SER   A  1 98  ? 82.255  -12.038 -5.680  1.00 40.02  ?  6896 SER   B N      1 
ATOM   1549 C  CA     . SER   A  1 98  ? 82.128  -10.954 -4.730  1.00 43.69  ?  6896 SER   B CA     1 
ATOM   1550 C  C      . SER   A  1 98  ? 82.693  -11.408 -3.397  1.00 37.52  ?  6896 SER   B C      1 
ATOM   1551 O  O      . SER   A  1 98  ? 82.635  -12.586 -3.044  1.00 41.46  ?  6896 SER   B O      1 
ATOM   1552 C  CB     . SER   A  1 98  ? 80.673  -10.503 -4.547  1.00 42.50  ?  6896 SER   B CB     1 
ATOM   1553 O  OG     . SER   A  1 98  ? 80.616  -9.399  -3.650  1.00 49.22  ?  6896 SER   B OG     1 
ATOM   1554 H  H      . SER   A  1 98  ? 82.305  -12.816 -5.316  1.00 48.54  ?  6896 SER   B H      1 
ATOM   1555 H  HA     . SER   A  1 98  ? 82.640  -10.196 -5.053  1.00 52.94  ?  6896 SER   B HA     1 
ATOM   1556 H  HB2    . SER   A  1 98  ? 80.312  -10.235 -5.406  1.00 51.52  ?  6896 SER   B HB2    1 
ATOM   1557 H  HB3    . SER   A  1 98  ? 80.155  -11.237 -4.183  1.00 51.52  ?  6896 SER   B HB3    1 
ATOM   1558 H  HG     . SER   A  1 98  ? 81.066  -8.759  -3.953  1.00 59.59  ?  6896 SER   B HG     1 
ATOM   1559 N  N      . ASP   A  1 99  ? 83.233  -10.453 -2.658  1.00 40.64  ?  6897 ASP   B N      1 
ATOM   1560 C  CA     . ASP   A  1 99  ? 83.614  -10.697 -1.280  1.00 42.41  ?  6897 ASP   B CA     1 
ATOM   1561 C  C      . ASP   A  1 99  ? 83.784  -9.347  -0.607  1.00 44.45  ?  6897 ASP   B C      1 
ATOM   1562 O  O      . ASP   A  1 99  ? 83.810  -8.299  -1.254  1.00 46.51  ?  6897 ASP   B O      1 
ATOM   1563 C  CB     . ASP   A  1 99  ? 84.872  -11.559 -1.183  1.00 40.50  ?  6897 ASP   B CB     1 
ATOM   1564 C  CG     . ASP   A  1 99  ? 84.996  -12.228 0.162   1.00 42.99  ?  6897 ASP   B CG     1 
ATOM   1565 O  OD1    . ASP   A  1 99  ? 84.928  -11.492 1.176   1.00 61.76  ?  6897 ASP   B OD1    1 
ATOM   1566 O  OD2    . ASP   A  1 99  ? 85.123  -13.475 0.189   1.00 43.05  ?  6897 ASP   B OD2    1 
ATOM   1567 H  H      . ASP   A  1 99  ? 83.388  -9.653  -2.933  1.00 49.29  ?  6897 ASP   B H      1 
ATOM   1568 H  HA     . ASP   A  1 99  ? 82.909  -11.179 -0.820  1.00 51.42  ?  6897 ASP   B HA     1 
ATOM   1569 H  HB2    . ASP   A  1 99  ? 84.839  -12.250 -1.863  1.00 49.12  ?  6897 ASP   B HB2    1 
ATOM   1570 H  HB3    . ASP   A  1 99  ? 85.653  -10.999 -1.316  1.00 49.12  ?  6897 ASP   B HB3    1 
ATOM   1571 N  N      . LEU   A  1 100 ? 83.895  -9.400  0.714   1.00 55.57  ?  6898 LEU   B N      1 
ATOM   1572 C  CA     . LEU   A  1 100 ? 83.948  -8.193  1.527   1.00 50.20  ?  6898 LEU   B CA     1 
ATOM   1573 C  C      . LEU   A  1 100 ? 85.215  -7.403  1.261   1.00 44.87  ?  6898 LEU   B C      1 
ATOM   1574 O  O      . LEU   A  1 100 ? 85.179  -6.175  1.124   1.00 48.13  ?  6898 LEU   B O      1 
ATOM   1575 C  CB     . LEU   A  1 100 ? 83.855  -8.596  2.995   1.00 52.02  ?  6898 LEU   B CB     1 
ATOM   1576 C  CG     . LEU   A  1 100 ? 83.827  -7.510  4.047   1.00 59.95  ?  6898 LEU   B CG     1 
ATOM   1577 C  CD1    . LEU   A  1 100 ? 82.546  -6.747  3.836   1.00 55.93  ?  6898 LEU   B CD1    1 
ATOM   1578 C  CD2    . LEU   A  1 100 ? 83.888  -8.150  5.401   1.00 54.73  ?  6898 LEU   B CD2    1 
ATOM   1579 H  H      . LEU   A  1 100 ? 83.943  -10.128 1.169   1.00 67.21  ?  6898 LEU   B H      1 
ATOM   1580 H  HA     . LEU   A  1 100 ? 83.199  -7.617  1.307   1.00 60.76  ?  6898 LEU   B HA     1 
ATOM   1581 H  HB2    . LEU   A  1 100 ? 83.038  -9.107  3.106   1.00 62.94  ?  6898 LEU   B HB2    1 
ATOM   1582 H  HB3    . LEU   A  1 100 ? 84.624  -9.153  3.194   1.00 62.94  ?  6898 LEU   B HB3    1 
ATOM   1583 H  HG     . LEU   A  1 100 ? 84.578  -6.898  3.989   1.00 72.46  ?  6898 LEU   B HG     1 
ATOM   1584 H  HD11   . LEU   A  1 100 ? 82.386  -6.179  4.607   1.00 67.64  ?  6898 LEU   B HD11   1 
ATOM   1585 H  HD12   . LEU   A  1 100 ? 82.630  -6.203  3.037   1.00 67.64  ?  6898 LEU   B HD12   1 
ATOM   1586 H  HD13   . LEU   A  1 100 ? 81.817  -7.377  3.732   1.00 67.64  ?  6898 LEU   B HD13   1 
ATOM   1587 H  HD21   . LEU   A  1 100 ? 83.846  -7.458  6.080   1.00 66.20  ?  6898 LEU   B HD21   1 
ATOM   1588 H  HD22   . LEU   A  1 100 ? 83.135  -8.755  5.498   1.00 66.20  ?  6898 LEU   B HD22   1 
ATOM   1589 H  HD23   . LEU   A  1 100 ? 84.720  -8.642  5.481   1.00 66.20  ?  6898 LEU   B HD23   1 
ATOM   1590 N  N      . ASN   A  1 101 ? 86.342  -8.091  1.187   1.00 50.41  ?  6899 ASN   B N      1 
ATOM   1591 C  CA     . ASN   A  1 101 ? 87.634  -7.451  1.030   1.00 51.42  ?  6899 ASN   B CA     1 
ATOM   1592 C  C      . ASN   A  1 101 ? 88.136  -7.604  -0.397  1.00 48.58  ?  6899 ASN   B C      1 
ATOM   1593 O  O      . ASN   A  1 101 ? 87.644  -8.427  -1.172  1.00 49.24  ?  6899 ASN   B O      1 
ATOM   1594 C  CB     . ASN   A  1 101 ? 88.630  -8.036  2.034   1.00 57.41  ?  6899 ASN   B CB     1 
ATOM   1595 C  CG     . ASN   A  1 101 ? 88.001  -8.290  3.397   1.00 58.46  ?  6899 ASN   B CG     1 
ATOM   1596 O  OD1    . ASN   A  1 101 ? 87.871  -9.429  3.833   1.00 58.18  ?  6899 ASN   B OD1    1 
ATOM   1597 N  ND2    . ASN   A  1 101 ? 87.541  -7.226  4.035   1.00 48.47  ?  6899 ASN   B ND2    1 
ATOM   1598 H  H      . ASN   A  1 101 ? 86.384  -8.949  1.227   1.00 61.02  ?  6899 ASN   B H      1 
ATOM   1599 H  HA     . ASN   A  1 101 ? 87.552  -6.500  1.206   1.00 62.23  ?  6899 ASN   B HA     1 
ATOM   1600 H  HB2    . ASN   A  1 101 ? 88.963  -8.881  1.694   1.00 69.41  ?  6899 ASN   B HB2    1 
ATOM   1601 H  HB3    . ASN   A  1 101 ? 89.364  -7.414  2.152   1.00 69.41  ?  6899 ASN   B HB3    1 
ATOM   1602 H  HD21   . ASN   A  1 101 ? 87.176  -7.313  4.809   1.00 58.69  ?  6899 ASN   B HD21   1 
ATOM   1603 H  HD22   . ASN   A  1 101 ? 87.608  -6.447  3.676   1.00 58.69  ?  6899 ASN   B HD22   1 
ATOM   1604 N  N      A ASP   A  1 102 ? 89.092  -6.751  -0.764  0.43 49.62  ?  6900 ASP   B N      1 
ATOM   1605 N  N      B ASP   A  1 102 ? 89.156  -6.821  -0.720  0.57 49.63  ?  6900 ASP   B N      1 
ATOM   1606 C  CA     A ASP   A  1 102 ? 89.607  -6.788  -2.126  0.43 48.69  ?  6900 ASP   B CA     1 
ATOM   1607 C  CA     B ASP   A  1 102 ? 89.705  -6.788  -2.063  0.57 48.70  ?  6900 ASP   B CA     1 
ATOM   1608 C  C      A ASP   A  1 102 ? 90.354  -8.092  -2.368  0.43 46.16  ?  6900 ASP   B C      1 
ATOM   1609 C  C      B ASP   A  1 102 ? 90.413  -8.106  -2.366  0.57 46.14  ?  6900 ASP   B C      1 
ATOM   1610 O  O      A ASP   A  1 102 ? 90.956  -8.667  -1.457  0.43 45.70  ?  6900 ASP   B O      1 
ATOM   1611 O  O      B ASP   A  1 102 ? 91.029  -8.712  -1.479  0.57 45.69  ?  6900 ASP   B O      1 
ATOM   1612 C  CB     A ASP   A  1 102 ? 90.525  -5.595  -2.414  0.43 49.00  ?  6900 ASP   B CB     1 
ATOM   1613 C  CB     B ASP   A  1 102 ? 90.679  -5.618  -2.152  0.57 48.75  ?  6900 ASP   B CB     1 
ATOM   1614 C  CG     A ASP   A  1 102 ? 91.104  -5.633  -3.829  0.43 53.34  ?  6900 ASP   B CG     1 
ATOM   1615 C  CG     B ASP   A  1 102 ? 90.158  -4.502  -3.033  0.57 51.75  ?  6900 ASP   B CG     1 
ATOM   1616 O  OD1    A ASP   A  1 102 ? 90.321  -5.732  -4.798  0.43 48.40  ?  6900 ASP   B OD1    1 
ATOM   1617 O  OD1    B ASP   A  1 102 ? 90.024  -4.713  -4.248  0.57 56.25  ?  6900 ASP   B OD1    1 
ATOM   1618 O  OD2    A ASP   A  1 102 ? 92.339  -5.534  -3.975  0.43 54.32  ?  6900 ASP   B OD2    1 
ATOM   1619 O  OD2    B ASP   A  1 102 ? 89.809  -3.422  -2.495  0.57 53.58  ?  6900 ASP   B OD2    1 
ATOM   1620 H  H      A ASP   A  1 102 ? 89.449  -6.157  -0.254  0.43 60.06  ?  6900 ASP   B H      1 
ATOM   1621 H  H      B ASP   A  1 102 ? 89.552  -6.292  -0.170  0.57 60.08  ?  6900 ASP   B H      1 
ATOM   1622 H  HA     A ASP   A  1 102 ? 88.863  -6.731  -2.746  0.43 58.95  ?  6900 ASP   B HA     1 
ATOM   1623 H  HA     B ASP   A  1 102 ? 89.009  -6.669  -2.728  0.57 58.96  ?  6900 ASP   B HA     1 
ATOM   1624 H  HB2    A ASP   A  1 102 ? 90.018  -4.774  -2.318  0.43 59.32  ?  6900 ASP   B HB2    1 
ATOM   1625 H  HB2    B ASP   A  1 102 ? 90.824  -5.258  -1.263  0.57 59.02  ?  6900 ASP   B HB2    1 
ATOM   1626 H  HB3    A ASP   A  1 102 ? 91.264  -5.604  -1.786  0.43 59.32  ?  6900 ASP   B HB3    1 
ATOM   1627 H  HB3    B ASP   A  1 102 ? 91.518  -5.931  -2.525  0.57 59.02  ?  6900 ASP   B HB3    1 
ATOM   1628 N  N      . PHE   A  1 103 ? 90.301  -8.561  -3.615  1.00 46.69  ?  6901 PHE   B N      1 
ATOM   1629 C  CA     . PHE   A  1 103 ? 90.996  -9.774  -4.030  1.00 45.04  ?  6901 PHE   B CA     1 
ATOM   1630 C  C      . PHE   A  1 103 ? 91.107  -9.803  -5.550  1.00 40.34  ?  6901 PHE   B C      1 
ATOM   1631 O  O      . PHE   A  1 103 ? 90.345  -9.142  -6.260  1.00 49.19  ?  6901 PHE   B O      1 
ATOM   1632 C  CB     . PHE   A  1 103 ? 90.305  -11.053 -3.506  1.00 44.35  ?  6901 PHE   B CB     1 
ATOM   1633 C  CG     . PHE   A  1 103 ? 88.911  -11.290 -4.052  1.00 44.89  ?  6901 PHE   B CG     1 
ATOM   1634 C  CD1    . PHE   A  1 103 ? 87.829  -10.624 -3.514  1.00 40.95  ?  6901 PHE   B CD1    1 
ATOM   1635 C  CD2    . PHE   A  1 103 ? 88.695  -12.205 -5.082  1.00 42.42  ?  6901 PHE   B CD2    1 
ATOM   1636 C  CE1    . PHE   A  1 103 ? 86.549  -10.844 -3.994  1.00 41.86  ?  6901 PHE   B CE1    1 
ATOM   1637 C  CE2    . PHE   A  1 103 ? 87.429  -12.427 -5.579  1.00 41.62  ?  6901 PHE   B CE2    1 
ATOM   1638 C  CZ     . PHE   A  1 103 ? 86.343  -11.747 -5.031  1.00 38.51  ?  6901 PHE   B CZ     1 
ATOM   1639 H  H      A PHE   A  1 103 ? 89.860  -8.185  -4.251  0.43 56.55  ?  6901 PHE   B H      1 
ATOM   1640 H  H      B PHE   A  1 103 ? 89.834  -8.187  -4.233  0.57 56.55  ?  6901 PHE   B H      1 
ATOM   1641 H  HA     . PHE   A  1 103 ? 91.895  -9.751  -3.667  1.00 54.57  ?  6901 PHE   B HA     1 
ATOM   1642 H  HB2    . PHE   A  1 103 ? 90.848  -11.818 -3.750  1.00 53.74  ?  6901 PHE   B HB2    1 
ATOM   1643 H  HB3    . PHE   A  1 103 ? 90.234  -10.990 -2.541  1.00 53.74  ?  6901 PHE   B HB3    1 
ATOM   1644 H  HD1    . PHE   A  1 103 ? 87.961  -10.019 -2.819  1.00 49.66  ?  6901 PHE   B HD1    1 
ATOM   1645 H  HD2    . PHE   A  1 103 ? 89.416  -12.673 -5.439  1.00 51.43  ?  6901 PHE   B HD2    1 
ATOM   1646 H  HE1    . PHE   A  1 103 ? 85.827  -10.388 -3.623  1.00 50.75  ?  6901 PHE   B HE1    1 
ATOM   1647 H  HE2    . PHE   A  1 103 ? 87.300  -13.027 -6.277  1.00 50.46  ?  6901 PHE   B HE2    1 
ATOM   1648 H  HZ     . PHE   A  1 103 ? 85.486  -11.896 -5.357  1.00 46.74  ?  6901 PHE   B HZ     1 
ATOM   1649 N  N      A VAL   A  1 104 ? 92.097  -10.546 -6.047  0.49 45.44  ?  6902 VAL   B N      1 
ATOM   1650 N  N      B VAL   A  1 104 ? 92.044  -10.624 -6.026  0.51 45.44  ?  6902 VAL   B N      1 
ATOM   1651 C  CA     A VAL   A  1 104 ? 92.273  -10.719 -7.489  0.49 44.67  ?  6902 VAL   B CA     1 
ATOM   1652 C  CA     B VAL   A  1 104 ? 92.326  -10.810 -7.447  0.51 44.66  ?  6902 VAL   B CA     1 
ATOM   1653 C  C      A VAL   A  1 104 ? 91.589  -12.013 -7.898  0.49 45.24  ?  6902 VAL   B C      1 
ATOM   1654 C  C      B VAL   A  1 104 ? 91.642  -12.078 -7.928  0.51 45.25  ?  6902 VAL   B C      1 
ATOM   1655 O  O      A VAL   A  1 104 ? 91.688  -13.032 -7.203  0.49 46.36  ?  6902 VAL   B O      1 
ATOM   1656 O  O      B VAL   A  1 104 ? 91.811  -13.147 -7.326  0.51 46.49  ?  6902 VAL   B O      1 
ATOM   1657 C  CB     A VAL   A  1 104 ? 93.758  -10.727 -7.907  0.49 44.21  ?  6902 VAL   B CB     1 
ATOM   1658 C  CB     B VAL   A  1 104 ? 93.841  -10.890 -7.696  0.51 44.04  ?  6902 VAL   B CB     1 
ATOM   1659 C  CG1    A VAL   A  1 104 ? 94.526  -9.658  -7.164  0.49 48.64  ?  6902 VAL   B CG1    1 
ATOM   1660 C  CG1    B VAL   A  1 104 ? 94.124  -11.349 -9.119  0.51 46.44  ?  6902 VAL   B CG1    1 
ATOM   1661 C  CG2    A VAL   A  1 104 ? 94.362  -12.105 -7.702  0.49 43.34  ?  6902 VAL   B CG2    1 
ATOM   1662 C  CG2    B VAL   A  1 104 ? 94.498  -9.548  -7.429  0.51 48.43  ?  6902 VAL   B CG2    1 
ATOM   1663 H  H      A VAL   A  1 104 ? 92.679  -10.960 -5.568  0.49 55.04  ?  6902 VAL   B H      1 
ATOM   1664 H  H      B VAL   A  1 104 ? 92.549  -11.104 -5.523  0.51 55.05  ?  6902 VAL   B H      1 
ATOM   1665 H  HA     A VAL   A  1 104 ? 91.852  -9.972  -7.943  0.49 54.13  ?  6902 VAL   B HA     1 
ATOM   1666 H  HA     B VAL   A  1 104 ? 91.961  -10.060 -7.942  0.51 54.12  ?  6902 VAL   B HA     1 
ATOM   1667 H  HB     A VAL   A  1 104 ? 93.824  -10.521 -8.853  0.49 53.57  ?  6902 VAL   B HB     1 
ATOM   1668 H  HB     B VAL   A  1 104 ? 94.223  -11.540 -7.086  0.51 53.37  ?  6902 VAL   B HB     1 
ATOM   1669 H  HG11   A VAL   A  1 104 ? 95.432  -9.624  -7.508  0.49 58.89  ?  6902 VAL   B HG11   1 
ATOM   1670 H  HG11   B VAL   A  1 104 ? 95.071  -11.245 -9.301  0.51 56.25  ?  6902 VAL   B HG11   1 
ATOM   1671 H  HG12   A VAL   A  1 104 ? 94.088  -8.803  -7.299  0.49 58.89  ?  6902 VAL   B HG12   1 
ATOM   1672 H  HG12   B VAL   A  1 104 ? 93.871  -12.282 -9.206  0.51 56.25  ?  6902 VAL   B HG12   1 
ATOM   1673 H  HG13   A VAL   A  1 104 ? 94.538  -9.877  -6.219  0.49 58.89  ?  6902 VAL   B HG13   1 
ATOM   1674 H  HG13   B VAL   A  1 104 ? 93.607  -10.807 -9.735  0.51 56.25  ?  6902 VAL   B HG13   1 
ATOM   1675 H  HG21   A VAL   A  1 104 ? 95.328  -12.028 -7.691  0.49 52.53  ?  6902 VAL   B HG21   1 
ATOM   1676 H  HG21   B VAL   A  1 104 ? 95.458  -9.639  -7.542  0.51 58.64  ?  6902 VAL   B HG21   1 
ATOM   1677 H  HG22   A VAL   A  1 104 ? 94.049  -12.465 -6.857  0.49 52.53  ?  6902 VAL   B HG22   1 
ATOM   1678 H  HG22   B VAL   A  1 104 ? 94.152  -8.896  -8.058  0.51 58.64  ?  6902 VAL   B HG22   1 
ATOM   1679 H  HG23   A VAL   A  1 104 ? 94.084  -12.683 -8.431  0.49 52.53  ?  6902 VAL   B HG23   1 
ATOM   1680 H  HG23   B VAL   A  1 104 ? 94.296  -9.273  -6.522  0.51 58.64  ?  6902 VAL   B HG23   1 
ATOM   1681 N  N      . SER   A  1 105 ? 90.902  -11.976 -9.035  1.00 42.30  ?  6903 SER   B N      1 
ATOM   1682 C  CA     . SER   A  1 105 ? 90.045  -13.063 -9.460  1.00 43.50  ?  6903 SER   B CA     1 
ATOM   1683 C  C      . SER   A  1 105 ? 90.102  -13.285 -10.961 1.00 43.06  ?  6903 SER   B C      1 
ATOM   1684 O  O      . SER   A  1 105 ? 90.428  -12.386 -11.730 1.00 41.95  ?  6903 SER   B O      1 
ATOM   1685 C  CB     . SER   A  1 105 ? 88.599  -12.777 -9.037  1.00 42.13  ?  6903 SER   B CB     1 
ATOM   1686 O  OG     . SER   A  1 105 ? 87.720  -13.767 -9.526  1.00 42.52  ?  6903 SER   B OG     1 
ATOM   1687 H  H      A SER   A  1 105 ? 90.921  -11.316 -9.586  0.49 51.28  ?  6903 SER   B H      1 
ATOM   1688 H  H      B SER   A  1 105 ? 90.886  -11.286 -9.549  0.51 51.28  ?  6903 SER   B H      1 
ATOM   1689 H  HA     . SER   A  1 105 ? 90.365  -13.886 -9.059  1.00 52.72  ?  6903 SER   B HA     1 
ATOM   1690 H  HB2    . SER   A  1 105 ? 88.551  -12.766 -8.068  1.00 51.08  ?  6903 SER   B HB2    1 
ATOM   1691 H  HB3    . SER   A  1 105 ? 88.331  -11.915 -9.392  1.00 51.08  ?  6903 SER   B HB3    1 
ATOM   1692 H  HG     . SER   A  1 105 ? 86.935  -13.601 -9.280  1.00 51.55  ?  6903 SER   B HG     1 
ATOM   1693 N  N      . ASP   A  1 106 ? 89.766  -14.510 -11.356 1.00 39.61  ?  6904 ASP   B N      1 
ATOM   1694 C  CA     . ASP   A  1 106 ? 89.605  -14.892 -12.739 1.00 40.78  ?  6904 ASP   B CA     1 
ATOM   1695 C  C      . ASP   A  1 106 ? 88.177  -14.702 -13.214 1.00 38.46  ?  6904 ASP   B C      1 
ATOM   1696 O  O      . ASP   A  1 106 ? 87.886  -14.994 -14.376 1.00 45.09  ?  6904 ASP   B O      1 
ATOM   1697 C  CB     . ASP   A  1 106 ? 90.022  -16.351 -12.931 1.00 38.35  ?  6904 ASP   B CB     1 
ATOM   1698 C  CG     . ASP   A  1 106 ? 91.494  -16.563 -12.672 1.00 36.91  ?  6904 ASP   B CG     1 
ATOM   1699 O  OD1    . ASP   A  1 106 ? 92.316  -16.027 -13.436 1.00 44.21  ?  6904 ASP   B OD1    1 
ATOM   1700 O  OD2    . ASP   A  1 106 ? 91.854  -17.217 -11.674 1.00 40.38  ?  6904 ASP   B OD2    1 
ATOM   1701 H  H      . ASP   A  1 106 ? 89.622  -15.161 -10.811 1.00 48.05  ?  6904 ASP   B H      1 
ATOM   1702 H  HA     . ASP   A  1 106 ? 90.186  -14.348 -13.292 1.00 49.46  ?  6904 ASP   B HA     1 
ATOM   1703 H  HB2    . ASP   A  1 106 ? 89.523  -16.909 -12.313 1.00 46.54  ?  6904 ASP   B HB2    1 
ATOM   1704 H  HB3    . ASP   A  1 106 ? 89.835  -16.618 -13.844 1.00 46.54  ?  6904 ASP   B HB3    1 
ATOM   1705 N  N      . ALA   A  1 107 ? 87.290  -14.206 -12.358 1.00 43.41  ?  6905 ALA   B N      1 
ATOM   1706 C  CA     . ALA   A  1 107 ? 85.919  -13.984 -12.759 1.00 41.96  ?  6905 ALA   B CA     1 
ATOM   1707 C  C      . ALA   A  1 107 ? 85.839  -12.815 -13.735 1.00 42.44  ?  6905 ALA   B C      1 
ATOM   1708 O  O      . ALA   A  1 107 ? 86.699  -11.933 -13.764 1.00 48.93  ?  6905 ALA   B O      1 
ATOM   1709 C  CB     . ALA   A  1 107 ? 85.030  -13.703 -11.548 1.00 39.58  ?  6905 ALA   B CB     1 
ATOM   1710 H  H      . ALA   A  1 107 ? 87.462  -13.993 -11.543 1.00 52.61  ?  6905 ALA   B H      1 
ATOM   1711 H  HA     . ALA   A  1 107 ? 85.582  -14.782 -13.194 1.00 50.87  ?  6905 ALA   B HA     1 
ATOM   1712 H  HB1    . ALA   A  1 107 ? 84.127  -13.525 -11.854 1.00 48.01  ?  6905 ALA   B HB1    1 
ATOM   1713 H  HB2    . ALA   A  1 107 ? 85.035  -14.478 -10.966 1.00 48.01  ?  6905 ALA   B HB2    1 
ATOM   1714 H  HB3    . ALA   A  1 107 ? 85.377  -12.931 -11.074 1.00 48.01  ?  6905 ALA   B HB3    1 
ATOM   1715 N  N      . ASP   A  1 108 ? 84.770  -12.819 -14.535 1.00 44.03  ?  6906 ASP   B N      1 
ATOM   1716 C  CA     . ASP   A  1 108 ? 84.563  -11.777 -15.533 1.00 44.44  ?  6906 ASP   B CA     1 
ATOM   1717 C  C      . ASP   A  1 108 ? 84.320  -10.417 -14.889 1.00 43.67  ?  6906 ASP   B C      1 
ATOM   1718 O  O      . ASP   A  1 108 ? 84.659  -9.380  -15.470 1.00 45.93  ?  6906 ASP   B O      1 
ATOM   1719 C  CB     . ASP   A  1 108 ? 83.379  -12.149 -16.422 1.00 43.16  ?  6906 ASP   B CB     1 
ATOM   1720 C  CG     . ASP   A  1 108 ? 83.606  -13.439 -17.171 1.00 42.98  ?  6906 ASP   B CG     1 
ATOM   1721 O  OD1    . ASP   A  1 108 ? 84.533  -13.485 -18.003 1.00 47.62  ?  6906 ASP   B OD1    1 
ATOM   1722 O  OD2    . ASP   A  1 108 ? 82.884  -14.424 -16.901 1.00 42.91  ?  6906 ASP   B OD2    1 
ATOM   1723 H  H      . ASP   A  1 108 ? 84.150  -13.414 -14.518 1.00 53.36  ?  6906 ASP   B H      1 
ATOM   1724 H  HA     . ASP   A  1 108 ? 85.359  -11.710 -16.084 1.00 53.86  ?  6906 ASP   B HA     1 
ATOM   1725 H  HB2    . ASP   A  1 108 ? 82.589  -12.256 -15.870 1.00 52.31  ?  6906 ASP   B HB2    1 
ATOM   1726 H  HB3    . ASP   A  1 108 ? 83.237  -11.444 -17.072 1.00 52.31  ?  6906 ASP   B HB3    1 
ATOM   1727 N  N      . SER   A  1 109 ? 83.704  -10.404 -13.712 1.00 41.92  ?  6907 SER   B N      1 
ATOM   1728 C  CA     . SER   A  1 109 ? 83.562  -9.196  -12.915 1.00 43.83  ?  6907 SER   B CA     1 
ATOM   1729 C  C      . SER   A  1 109 ? 83.602  -9.572  -11.447 1.00 36.96  ?  6907 SER   B C      1 
ATOM   1730 O  O      . SER   A  1 109 ? 83.081  -10.612 -11.045 1.00 41.83  ?  6907 SER   B O      1 
ATOM   1731 C  CB     . SER   A  1 109 ? 82.254  -8.450  -13.202 1.00 43.71  ?  6907 SER   B CB     1 
ATOM   1732 O  OG     . SER   A  1 109 ? 82.345  -7.646  -14.360 1.00 67.72  ?  6907 SER   B OG     1 
ATOM   1733 H  H      . SER   A  1 109 ? 83.352  -11.098 -13.347 1.00 50.82  ?  6907 SER   B H      1 
ATOM   1734 H  HA     . SER   A  1 109 ? 84.301  -8.602  -13.122 1.00 53.12  ?  6907 SER   B HA     1 
ATOM   1735 H  HB2    . SER   A  1 109 ? 81.547  -9.101  -13.330 1.00 52.98  ?  6907 SER   B HB2    1 
ATOM   1736 H  HB3    . SER   A  1 109 ? 82.048  -7.880  -12.444 1.00 52.98  ?  6907 SER   B HB3    1 
ATOM   1737 H  HG     . SER   A  1 109 ? 81.630  -7.217  -14.469 1.00 81.79  ?  6907 SER   B HG     1 
ATOM   1738 N  N      . THR   A  1 110 ? 84.203  -8.695  -10.652 1.00 46.43  ?  6908 THR   B N      1 
ATOM   1739 C  CA     . THR   A  1 110 ? 84.319  -8.869  -9.211  1.00 44.56  ?  6908 THR   B CA     1 
ATOM   1740 C  C      . THR   A  1 110 ? 83.760  -7.629  -8.535  1.00 40.14  ?  6908 THR   B C      1 
ATOM   1741 O  O      . THR   A  1 110 ? 84.114  -6.509  -8.906  1.00 45.00  ?  6908 THR   B O      1 
ATOM   1742 C  CB     . THR   A  1 110 ? 85.775  -9.084  -8.800  1.00 40.95  ?  6908 THR   B CB     1 
ATOM   1743 O  OG1    . THR   A  1 110 ? 86.277  -10.287 -9.404  1.00 42.99  ?  6908 THR   B OG1    1 
ATOM   1744 C  CG2    . THR   A  1 110 ? 85.906  -9.172  -7.294  1.00 43.91  ?  6908 THR   B CG2    1 
ATOM   1745 H  H      . THR   A  1 110 ? 84.564  -7.967  -10.934 1.00 56.24  ?  6908 THR   B H      1 
ATOM   1746 H  HA     . THR   A  1 110 ? 83.806  -9.640  -8.925  1.00 54.00  ?  6908 THR   B HA     1 
ATOM   1747 H  HB     . THR   A  1 110 ? 86.307  -8.330  -9.100  1.00 49.66  ?  6908 THR   B HB     1 
ATOM   1748 H  HG1    . THR   A  1 110 ? 85.820  -10.946 -9.155  1.00 52.11  ?  6908 THR   B HG1    1 
ATOM   1749 H  HG21   . THR   A  1 110 ? 86.757  -9.574  -7.058  1.00 53.21  ?  6908 THR   B HG21   1 
ATOM   1750 H  HG22   . THR   A  1 110 ? 85.858  -8.285  -6.905  1.00 53.21  ?  6908 THR   B HG22   1 
ATOM   1751 H  HG23   . THR   A  1 110 ? 85.190  -9.715  -6.930  1.00 53.21  ?  6908 THR   B HG23   1 
ATOM   1752 N  N      . LEU   A  1 111 ? 82.908  -7.830  -7.536  1.00 48.21  ?  6909 LEU   B N      1 
ATOM   1753 C  CA     . LEU   A  1 111 ? 82.362  -6.747  -6.734  1.00 40.91  ?  6909 LEU   B CA     1 
ATOM   1754 C  C      . LEU   A  1 111 ? 82.884  -6.880  -5.318  1.00 40.66  ?  6909 LEU   B C      1 
ATOM   1755 O  O      . LEU   A  1 111 ? 82.781  -7.948  -4.712  1.00 43.35  ?  6909 LEU   B O      1 
ATOM   1756 C  CB     . LEU   A  1 111 ? 80.839  -6.776  -6.753  1.00 39.62  ?  6909 LEU   B CB     1 
ATOM   1757 C  CG     . LEU   A  1 111 ? 80.289  -6.447  -8.134  1.00 44.22  ?  6909 LEU   B CG     1 
ATOM   1758 C  CD1    . LEU   A  1 111 ? 78.763  -6.650  -8.070  1.00 41.16  ?  6909 LEU   B CD1    1 
ATOM   1759 C  CD2    . LEU   A  1 111 ? 80.592  -5.026  -8.533  1.00 52.82  ?  6909 LEU   B CD2    1 
ATOM   1760 H  H      . LEU   A  1 111 ? 82.626  -8.607  -7.299  1.00 58.38  ?  6909 LEU   B H      1 
ATOM   1761 H  HA     . LEU   A  1 111 ? 82.648  -5.890  -7.087  1.00 49.61  ?  6909 LEU   B HA     1 
ATOM   1762 H  HB2    . LEU   A  1 111 ? 80.534  -7.662  -6.505  1.00 48.07  ?  6909 LEU   B HB2    1 
ATOM   1763 H  HB3    . LEU   A  1 111 ? 80.500  -6.120  -6.124  1.00 48.07  ?  6909 LEU   B HB3    1 
ATOM   1764 H  HG     . LEU   A  1 111 ? 80.697  -7.018  -8.803  1.00 53.58  ?  6909 LEU   B HG     1 
ATOM   1765 H  HD11   . LEU   A  1 111 ? 78.378  -6.421  -8.930  1.00 49.91  ?  6909 LEU   B HD11   1 
ATOM   1766 H  HD12   . LEU   A  1 111 ? 78.577  -7.578  -7.859  1.00 49.91  ?  6909 LEU   B HD12   1 
ATOM   1767 H  HD13   . LEU   A  1 111 ? 78.397  -6.074  -7.380  1.00 49.91  ?  6909 LEU   B HD13   1 
ATOM   1768 H  HD21   . LEU   A  1 111 ? 79.796  -4.630  -8.920  1.00 63.91  ?  6909 LEU   B HD21   1 
ATOM   1769 H  HD22   . LEU   A  1 111 ? 80.860  -4.527  -7.745  1.00 63.91  ?  6909 LEU   B HD22   1 
ATOM   1770 H  HD23   . LEU   A  1 111 ? 81.311  -5.027  -9.184  1.00 63.91  ?  6909 LEU   B HD23   1 
ATOM   1771 N  N      . ILE   A  1 112 ? 83.450  -5.800  -4.803  1.00 47.73  ?  6910 ILE   B N      1 
ATOM   1772 C  CA     . ILE   A  1 112 ? 84.008  -5.775  -3.463  1.00 45.12  ?  6910 ILE   B CA     1 
ATOM   1773 C  C      . ILE   A  1 112 ? 83.018  -5.058  -2.554  1.00 42.61  ?  6910 ILE   B C      1 
ATOM   1774 O  O      . ILE   A  1 112 ? 82.535  -3.973  -2.891  1.00 49.93  ?  6910 ILE   B O      1 
ATOM   1775 C  CB     . ILE   A  1 112 ? 85.381  -5.088  -3.459  1.00 43.53  ?  6910 ILE   B CB     1 
ATOM   1776 C  CG1    . ILE   A  1 112 ? 86.290  -5.736  -4.511  1.00 44.56  ?  6910 ILE   B CG1    1 
ATOM   1777 C  CG2    . ILE   A  1 112 ? 86.016  -5.180  -2.061  1.00 44.30  ?  6910 ILE   B CG2    1 
ATOM   1778 C  CD1    . ILE   A  1 112 ? 86.450  -7.238  -4.285  1.00 43.29  ?  6910 ILE   B CD1    1 
ATOM   1779 H  H      . ILE   A  1 112 ? 83.523  -5.052  -5.221  1.00 57.80  ?  6910 ILE   B H      1 
ATOM   1780 H  HA     . ILE   A  1 112 ? 84.124  -6.678  -3.131  1.00 54.67  ?  6910 ILE   B HA     1 
ATOM   1781 H  HB     . ILE   A  1 112 ? 85.267  -4.151  -3.683  1.00 52.76  ?  6910 ILE   B HB     1 
ATOM   1782 H  HG12   . ILE   A  1 112 ? 85.905  -5.601  -5.391  1.00 53.99  ?  6910 ILE   B HG12   1 
ATOM   1783 H  HG13   . ILE   A  1 112 ? 87.169  -5.327  -4.468  1.00 53.99  ?  6910 ILE   B HG13   1 
ATOM   1784 H  HG21   . ILE   A  1 112 ? 86.961  -4.972  -2.129  1.00 53.69  ?  6910 ILE   B HG21   1 
ATOM   1785 H  HG22   . ILE   A  1 112 ? 85.579  -4.545  -1.473  1.00 53.69  ?  6910 ILE   B HG22   1 
ATOM   1786 H  HG23   . ILE   A  1 112 ? 85.899  -6.081  -1.720  1.00 53.69  ?  6910 ILE   B HG23   1 
ATOM   1787 H  HD11   . ILE   A  1 112 ? 87.160  -7.569  -4.856  1.00 52.48  ?  6910 ILE   B HD11   1 
ATOM   1788 H  HD12   . ILE   A  1 112 ? 86.674  -7.395  -3.354  1.00 52.48  ?  6910 ILE   B HD12   1 
ATOM   1789 H  HD13   . ILE   A  1 112 ? 85.615  -7.681  -4.503  1.00 52.48  ?  6910 ILE   B HD13   1 
ATOM   1790 N  N      . GLY   A  1 113 ? 82.709  -5.667  -1.407  1.00 45.11  ?  6911 GLY   B N      1 
ATOM   1791 C  CA     . GLY   A  1 113 ? 81.822  -5.076  -0.436  1.00 42.04  ?  6911 GLY   B CA     1 
ATOM   1792 C  C      . GLY   A  1 113 ? 80.927  -6.083  0.262   1.00 42.53  ?  6911 GLY   B C      1 
ATOM   1793 O  O      . GLY   A  1 113 ? 80.903  -7.264  -0.105  1.00 50.38  ?  6911 GLY   B O      1 
ATOM   1794 H  H      . GLY   A  1 113 ? 83.011  -6.438  -1.174  1.00 54.65  ?  6911 GLY   B H      1 
ATOM   1795 H  HA2    . GLY   A  1 113 ? 82.350  -4.624  0.240   1.00 50.97  ?  6911 GLY   B HA2    1 
ATOM   1796 H  HA3    . GLY   A  1 113 ? 81.254  -4.427  -0.880  1.00 50.97  ?  6911 GLY   B HA3    1 
ATOM   1797 N  N      . ASP   A  1 114 ? 80.190  -5.633  1.289   1.00 48.44  ?  6912 ASP   B N      1 
ATOM   1798 C  CA     . ASP   A  1 114 ? 79.166  -6.478  1.885   1.00 46.64  ?  6912 ASP   B CA     1 
ATOM   1799 C  C      . ASP   A  1 114 ? 78.206  -6.943  0.802   1.00 41.06  ?  6912 ASP   B C      1 
ATOM   1800 O  O      . ASP   A  1 114 ? 77.843  -6.179  -0.087  1.00 46.75  ?  6912 ASP   B O      1 
ATOM   1801 C  CB     . ASP   A  1 114 ? 78.386  -5.758  2.991   1.00 48.49  ?  6912 ASP   B CB     1 
ATOM   1802 C  CG     . ASP   A  1 114 ? 77.497  -6.711  3.785   1.00 47.83  ?  6912 ASP   B CG     1 
ATOM   1803 O  OD1    . ASP   A  1 114 ? 77.990  -7.360  4.716   1.00 59.65  ?  6912 ASP   B OD1    1 
ATOM   1804 O  OD2    . ASP   A  1 114 ? 76.290  -6.792  3.490   1.00 52.40  ?  6912 ASP   B OD2    1 
ATOM   1805 H  H      . ASP   A  1 114 ? 80.267  -4.855  1.647   1.00 58.65  ?  6912 ASP   B H      1 
ATOM   1806 H  HA     . ASP   A  1 114 ? 79.599  -7.239  2.302   1.00 56.48  ?  6912 ASP   B HA     1 
ATOM   1807 H  HB2    . ASP   A  1 114 ? 79.013  -5.347  3.607   1.00 58.71  ?  6912 ASP   B HB2    1 
ATOM   1808 H  HB3    . ASP   A  1 114 ? 77.819  -5.080  2.592   1.00 58.71  ?  6912 ASP   B HB3    1 
ATOM   1809 N  N      . CYS   A  1 115 ? 77.796  -8.208  0.885   1.00 44.96  ?  6913 CYS   B N      1 
ATOM   1810 C  CA     . CYS   A  1 115 ? 76.928  -8.793  -0.133  1.00 46.66  ?  6913 CYS   B CA     1 
ATOM   1811 C  C      . CYS   A  1 115 ? 75.608  -8.046  -0.265  1.00 42.20  ?  6913 CYS   B C      1 
ATOM   1812 O  O      . CYS   A  1 115 ? 74.996  -8.058  -1.340  1.00 41.80  ?  6913 CYS   B O      1 
ATOM   1813 C  CB     . CYS   A  1 115 ? 76.730  -10.271 0.197   1.00 41.53  ?  6913 CYS   B CB     1 
ATOM   1814 S  SG     . CYS   A  1 115 ? 75.719  -10.590 1.664   1.00 44.76  ?  6913 CYS   B SG     1 
ATOM   1815 H  H      . CYS   A  1 115 ? 78.007  -8.749  1.519   1.00 54.47  ?  6913 CYS   B H      1 
ATOM   1816 H  HA     . CYS   A  1 115 ? 77.346  -8.733  -1.006  1.00 56.51  ?  6913 CYS   B HA     1 
ATOM   1817 H  HB2    . CYS   A  1 115 ? 76.295  -10.699 -0.556  1.00 50.36  ?  6913 CYS   B HB2    1 
ATOM   1818 H  HB3    . CYS   A  1 115 ? 77.600  -10.672 0.349   1.00 50.36  ?  6913 CYS   B HB3    1 
ATOM   1819 H  HG     . CYS   A  1 115 ? 75.560  -11.774 1.779   1.00 54.23  ?  6913 CYS   B HG     1 
ATOM   1820 N  N      . ALA   A  1 116 ? 75.175  -7.364  0.797   1.00 48.81  ?  6914 ALA   B N      1 
ATOM   1821 C  CA     . ALA   A  1 116 ? 73.930  -6.609  0.735   1.00 45.61  ?  6914 ALA   B CA     1 
ATOM   1822 C  C      . ALA   A  1 116 ? 74.029  -5.424  -0.216  1.00 43.09  ?  6914 ALA   B C      1 
ATOM   1823 O  O      . ALA   A  1 116 ? 72.993  -4.922  -0.664  1.00 45.95  ?  6914 ALA   B O      1 
ATOM   1824 C  CB     . ALA   A  1 116 ? 73.508  -6.119  2.119   1.00 45.80  ?  6914 ALA   B CB     1 
ATOM   1825 H  H      . ALA   A  1 116 ? 75.581  -7.324  1.554   1.00 59.10  ?  6914 ALA   B H      1 
ATOM   1826 H  HA     . ALA   A  1 116 ? 73.236  -7.207  0.418   1.00 55.26  ?  6914 ALA   B HA     1 
ATOM   1827 H  HB1    . ALA   A  1 116 ? 72.684  -5.614  2.037   1.00 55.48  ?  6914 ALA   B HB1    1 
ATOM   1828 H  HB2    . ALA   A  1 116 ? 73.370  -6.885  2.697   1.00 55.48  ?  6914 ALA   B HB2    1 
ATOM   1829 H  HB3    . ALA   A  1 116 ? 74.208  -5.553  2.481   1.00 55.48  ?  6914 ALA   B HB3    1 
ATOM   1830 N  N      . THR   A  1 117 ? 75.241  -4.951  -0.524  1.00 45.72  ?  6915 THR   B N      1 
ATOM   1831 C  CA     . THR   A  1 117 ? 75.384  -3.877  -1.502  1.00 48.99  ?  6915 THR   B CA     1 
ATOM   1832 C  C      . THR   A  1 117 ? 75.286  -4.362  -2.947  1.00 48.26  ?  6915 THR   B C      1 
ATOM   1833 O  O      . THR   A  1 117 ? 75.383  -3.544  -3.867  1.00 50.17  ?  6915 THR   B O      1 
ATOM   1834 C  CB     . THR   A  1 117 ? 76.729  -3.148  -1.348  1.00 36.92  ?  6915 THR   B CB     1 
ATOM   1835 O  OG1    . THR   A  1 117 ? 77.780  -3.952  -1.888  1.00 45.85  ?  6915 THR   B OG1    1 
ATOM   1836 C  CG2    . THR   A  1 117 ? 77.030  -2.828  0.089   1.00 43.92  ?  6915 THR   B CG2    1 
ATOM   1837 H  H      . THR   A  1 117 ? 75.980  -5.233  -0.186  1.00 55.38  ?  6915 THR   B H      1 
ATOM   1838 H  HA     . THR   A  1 117 ? 74.670  -3.244  -1.323  1.00 59.30  ?  6915 THR   B HA     1 
ATOM   1839 H  HB     . THR   A  1 117 ? 76.680  -2.308  -1.830  1.00 44.83  ?  6915 THR   B HB     1 
ATOM   1840 H  HG1    . THR   A  1 117 ? 77.852  -4.664  -1.448  1.00 55.54  ?  6915 THR   B HG1    1 
ATOM   1841 H  HG21   . THR   A  1 117 ? 77.804  -2.246  0.144   1.00 53.22  ?  6915 THR   B HG21   1 
ATOM   1842 H  HG22   . THR   A  1 117 ? 76.271  -2.382  0.495   1.00 53.22  ?  6915 THR   B HG22   1 
ATOM   1843 H  HG23   . THR   A  1 117 ? 77.214  -3.645  0.579   1.00 53.22  ?  6915 THR   B HG23   1 
ATOM   1844 N  N      . VAL   A  1 118 ? 75.122  -5.657  -3.185  1.00 52.20  ?  6916 VAL   B N      1 
ATOM   1845 C  CA     . VAL   A  1 118 ? 75.153  -6.207  -4.537  1.00 46.93  ?  6916 VAL   B CA     1 
ATOM   1846 C  C      . VAL   A  1 118 ? 73.763  -6.249  -5.137  1.00 44.93  ?  6916 VAL   B C      1 
ATOM   1847 O  O      . VAL   A  1 118 ? 72.833  -6.796  -4.536  1.00 47.50  ?  6916 VAL   B O      1 
ATOM   1848 C  CB     . VAL   A  1 118 ? 75.777  -7.609  -4.552  1.00 45.03  ?  6916 VAL   B CB     1 
ATOM   1849 C  CG1    . VAL   A  1 118 ? 75.686  -8.216  -5.947  1.00 46.75  ?  6916 VAL   B CG1    1 
ATOM   1850 C  CG2    . VAL   A  1 118 ? 77.250  -7.531  -4.146  1.00 44.12  ?  6916 VAL   B CG2    1 
ATOM   1851 H  H      . VAL   A  1 118 ? 74.989  -6.247  -2.573  1.00 63.16  ?  6916 VAL   B H      1 
ATOM   1852 H  HA     . VAL   A  1 118 ? 75.689  -5.607  -5.080  1.00 56.84  ?  6916 VAL   B HA     1 
ATOM   1853 H  HB     . VAL   A  1 118 ? 75.294  -8.169  -3.925  1.00 54.56  ?  6916 VAL   B HB     1 
ATOM   1854 H  HG11   . VAL   A  1 118 ? 76.326  -8.941  -6.019  1.00 56.63  ?  6916 VAL   B HG11   1 
ATOM   1855 H  HG12   . VAL   A  1 118 ? 74.787  -8.553  -6.087  1.00 56.63  ?  6916 VAL   B HG12   1 
ATOM   1856 H  HG13   . VAL   A  1 118 ? 75.887  -7.531  -6.603  1.00 56.63  ?  6916 VAL   B HG13   1 
ATOM   1857 H  HG21   . VAL   A  1 118 ? 77.623  -8.426  -4.138  1.00 53.47  ?  6916 VAL   B HG21   1 
ATOM   1858 H  HG22   . VAL   A  1 118 ? 77.725  -6.981  -4.788  1.00 53.47  ?  6916 VAL   B HG22   1 
ATOM   1859 H  HG23   . VAL   A  1 118 ? 77.313  -7.138  -3.262  1.00 53.47  ?  6916 VAL   B HG23   1 
ATOM   1860 N  N      . HIS   A  1 119 ? 73.646  -5.722  -6.357  1.00 47.13  ?  6917 HIS   B N      1 
ATOM   1861 C  CA     . HIS   A  1 119 ? 72.410  -5.743  -7.115  1.00 46.39  ?  6917 HIS   B CA     1 
ATOM   1862 C  C      . HIS   A  1 119 ? 72.707  -6.169  -8.536  1.00 40.87  ?  6917 HIS   B C      1 
ATOM   1863 O  O      . HIS   A  1 119 ? 73.755  -5.842  -9.094  1.00 47.31  ?  6917 HIS   B O      1 
ATOM   1864 C  CB     . HIS   A  1 119 ? 71.734  -4.374  -7.123  1.00 46.88  ?  6917 HIS   B CB     1 
ATOM   1865 C  CG     . HIS   A  1 119 ? 71.551  -3.815  -5.757  1.00 55.22  ?  6917 HIS   B CG     1 
ATOM   1866 N  ND1    . HIS   A  1 119 ? 70.424  -4.066  -5.008  1.00 59.77  ?  6917 HIS   B ND1    1 
ATOM   1867 C  CD2    . HIS   A  1 119 ? 72.359  -3.052  -4.987  1.00 56.44  ?  6917 HIS   B CD2    1 
ATOM   1868 C  CE1    . HIS   A  1 119 ? 70.543  -3.478  -3.834  1.00 57.45  ?  6917 HIS   B CE1    1 
ATOM   1869 N  NE2    . HIS   A  1 119 ? 71.703  -2.848  -3.797  1.00 58.75  ?  6917 HIS   B NE2    1 
ATOM   1870 H  H      . HIS   A  1 119 ? 74.293  -5.337  -6.773  1.00 57.08  ?  6917 HIS   B H      1 
ATOM   1871 H  HA     . HIS   A  1 119 ? 71.795  -6.381  -6.719  1.00 56.18  ?  6917 HIS   B HA     1 
ATOM   1872 H  HB2    . HIS   A  1 119 ? 72.282  -3.755  -7.630  1.00 56.77  ?  6917 HIS   B HB2    1 
ATOM   1873 H  HB3    . HIS   A  1 119 ? 70.859  -4.457  -7.534  1.00 56.77  ?  6917 HIS   B HB3    1 
ATOM   1874 H  HD2    . HIS   A  1 119 ? 73.200  -2.727  -5.218  1.00 68.25  ?  6917 HIS   B HD2    1 
ATOM   1875 H  HE1    . HIS   A  1 119 ? 69.916  -3.503  -3.147  1.00 69.46  ?  6917 HIS   B HE1    1 
ATOM   1876 H  HE2    . HIS   A  1 119 ? 72.000  -2.385  -3.136  1.00 71.02  ?  6917 HIS   B HE2    1 
ATOM   1877 N  N      . THR   A  1 120 ? 71.768  -6.884  -9.129  1.00 43.19  ?  6918 THR   B N      1 
ATOM   1878 C  CA     . THR   A  1 120 ? 71.895  -7.259  -10.529 1.00 48.49  ?  6918 THR   B CA     1 
ATOM   1879 C  C      . THR   A  1 120 ? 70.548  -7.065  -11.194 1.00 49.25  ?  6918 THR   B C      1 
ATOM   1880 O  O      . THR   A  1 120 ? 69.504  -7.315  -10.580 1.00 53.66  ?  6918 THR   B O      1 
ATOM   1881 C  CB     . THR   A  1 120 ? 72.384  -8.700  -10.680 1.00 48.69  ?  6918 THR   B CB     1 
ATOM   1882 O  OG1    . THR   A  1 120 ? 71.334  -9.615  -10.349 1.00 57.41  ?  6918 THR   B OG1    1 
ATOM   1883 C  CG2    . THR   A  1 120 ? 73.582  -8.938  -9.773  1.00 57.65  ?  6918 THR   B CG2    1 
ATOM   1884 H  H      . THR   A  1 120 ? 71.051  -7.164  -8.745  1.00 52.34  ?  6918 THR   B H      1 
ATOM   1885 H  HA     . THR   A  1 120 ? 72.541  -6.692  -10.979 1.00 58.71  ?  6918 THR   B HA     1 
ATOM   1886 H  HB     . THR   A  1 120 ? 72.653  -8.860  -11.599 1.00 58.96  ?  6918 THR   B HB     1 
ATOM   1887 H  HG1    . THR   A  1 120 ? 70.756  -9.622  -10.958 1.00 69.41  ?  6918 THR   B HG1    1 
ATOM   1888 H  HG21   . THR   A  1 120 ? 73.994  -9.790  -9.984  1.00 69.70  ?  6918 THR   B HG21   1 
ATOM   1889 H  HG22   . THR   A  1 120 ? 74.237  -8.233  -9.896  1.00 69.70  ?  6918 THR   B HG22   1 
ATOM   1890 H  HG23   . THR   A  1 120 ? 73.299  -8.946  -8.845  1.00 69.70  ?  6918 THR   B HG23   1 
ATOM   1891 N  N      . ALA   A  1 121 ? 70.587  -6.602  -12.444 1.00 54.84  ?  6919 ALA   B N      1 
ATOM   1892 C  CA     . ALA   A  1 121 ? 69.370  -6.452  -13.225 1.00 65.82  ?  6919 ALA   B CA     1 
ATOM   1893 C  C      . ALA   A  1 121 ? 68.737  -7.803  -13.525 1.00 61.40  ?  6919 ALA   B C      1 
ATOM   1894 O  O      . ALA   A  1 121 ? 67.525  -7.976  -13.360 1.00 57.16  ?  6919 ALA   B O      1 
ATOM   1895 C  CB     . ALA   A  1 121 ? 69.699  -5.714  -14.523 1.00 56.08  ?  6919 ALA   B CB     1 
ATOM   1896 H  H      . ALA   A  1 121 ? 71.304  -6.370  -12.859 1.00 66.33  ?  6919 ALA   B H      1 
ATOM   1897 H  HA     . ALA   A  1 121 ? 68.725  -5.929  -12.722 1.00 79.50  ?  6919 ALA   B HA     1 
ATOM   1898 H  HB1    . ALA   A  1 121 ? 68.921  -5.732  -15.103 1.00 67.82  ?  6919 ALA   B HB1    1 
ATOM   1899 H  HB2    . ALA   A  1 121 ? 69.934  -4.796  -14.314 1.00 67.82  ?  6919 ALA   B HB2    1 
ATOM   1900 H  HB3    . ALA   A  1 121 ? 70.445  -6.156  -14.957 1.00 67.82  ?  6919 ALA   B HB3    1 
ATOM   1901 N  N      . ASN   A  1 122 ? 69.572  -8.784  -13.830 1.00 54.45  ?  6920 ASN   B N      1 
ATOM   1902 C  CA     . ASN   A  1 122 ? 69.254  -10.060 -14.439 1.00 61.28  ?  6920 ASN   B CA     1 
ATOM   1903 C  C      . ASN   A  1 122 ? 69.222  -11.190 -13.424 1.00 48.42  ?  6920 ASN   B C      1 
ATOM   1904 O  O      . ASN   A  1 122 ? 69.607  -11.034 -12.267 1.00 51.45  ?  6920 ASN   B O      1 
ATOM   1905 C  CB     . ASN   A  1 122 ? 70.301  -10.302 -15.522 1.00 58.69  ?  6920 ASN   B CB     1 
ATOM   1906 C  CG     . ASN   A  1 122 ? 71.700  -10.392 -14.941 1.00 65.04  ?  6920 ASN   B CG     1 
ATOM   1907 O  OD1    . ASN   A  1 122 ? 72.433  -9.403  -14.904 1.00 60.56  ?  6920 ASN   B OD1    1 
ATOM   1908 N  ND2    . ASN   A  1 122 ? 72.076  -11.555 -14.483 1.00 61.59  ?  6920 ASN   B ND2    1 
ATOM   1909 H  H      . ASN   A  1 122 ? 70.416  -8.726  -13.677 1.00 65.87  ?  6920 ASN   B H      1 
ATOM   1910 H  HA     . ASN   A  1 122 ? 68.364  -10.049 -14.823 1.00 74.05  ?  6920 ASN   B HA     1 
ATOM   1911 H  HB2    . ASN   A  1 122 ? 70.105  -11.137 -15.975 1.00 70.96  ?  6920 ASN   B HB2    1 
ATOM   1912 H  HB3    . ASN   A  1 122 ? 70.281  -9.568  -16.156 1.00 70.96  ?  6920 ASN   B HB3    1 
ATOM   1913 H  HD21   . ASN   A  1 122 ? 71.538  -12.225 -14.519 1.00 74.43  ?  6920 ASN   B HD21   1 
ATOM   1914 H  HD22   . ASN   A  1 122 ? 72.861  -11.651 -14.144 1.00 74.43  ?  6920 ASN   B HD22   1 
ATOM   1915 N  N      . LYS   A  1 123 ? 68.720  -12.335 -13.875 1.00 51.38  ?  6921 LYS   B N      1 
ATOM   1916 C  CA     . LYS   A  1 123 ? 68.628  -13.525 -13.049 1.00 44.61  ?  6921 LYS   B CA     1 
ATOM   1917 C  C      . LYS   A  1 123 ? 69.800  -14.449 -13.346 1.00 43.83  ?  6921 LYS   B C      1 
ATOM   1918 O  O      . LYS   A  1 123 ? 70.500  -14.311 -14.353 1.00 49.19  ?  6921 LYS   B O      1 
ATOM   1919 C  CB     . LYS   A  1 123 ? 67.300  -14.242 -13.261 1.00 43.24  ?  6921 LYS   B CB     1 
ATOM   1920 C  CG     . LYS   A  1 123 ? 66.130  -13.429 -12.801 1.00 50.19  ?  6921 LYS   B CG     1 
ATOM   1921 C  CD     . LYS   A  1 123 ? 64.964  -14.318 -12.442 1.00 48.59  ?  6921 LYS   B CD     1 
ATOM   1922 C  CE     . LYS   A  1 123 ? 63.778  -13.480 -11.986 1.00 54.63  ?  6921 LYS   B CE     1 
ATOM   1923 N  NZ     . LYS   A  1 123 ? 62.879  -14.296 -11.150 1.00 76.82  ?  6921 LYS   B NZ     1 
ATOM   1924 H  H      . LYS   A  1 123 ? 68.421  -12.445 -14.673 1.00 62.17  ?  6921 LYS   B H      1 
ATOM   1925 H  HA     . LYS   A  1 123 ? 68.666  -13.271 -12.114 1.00 54.05  ?  6921 LYS   B HA     1 
ATOM   1926 H  HB2    . LYS   A  1 123 ? 67.186  -14.425 -14.207 1.00 52.41  ?  6921 LYS   B HB2    1 
ATOM   1927 H  HB3    . LYS   A  1 123 ? 67.305  -15.073 -12.760 1.00 52.41  ?  6921 LYS   B HB3    1 
ATOM   1928 H  HG2    . LYS   A  1 123 ? 66.380  -12.917 -12.015 1.00 60.75  ?  6921 LYS   B HG2    1 
ATOM   1929 H  HG3    . LYS   A  1 123 ? 65.852  -12.830 -13.512 1.00 60.75  ?  6921 LYS   B HG3    1 
ATOM   1930 H  HD2    . LYS   A  1 123 ? 64.697  -14.834 -13.219 1.00 58.83  ?  6921 LYS   B HD2    1 
ATOM   1931 H  HD3    . LYS   A  1 123 ? 65.219  -14.913 -11.719 1.00 58.83  ?  6921 LYS   B HD3    1 
ATOM   1932 H  HE2    . LYS   A  1 123 ? 64.092  -12.726 -11.462 1.00 66.08  ?  6921 LYS   B HE2    1 
ATOM   1933 H  HE3    . LYS   A  1 123 ? 63.283  -13.165 -12.759 1.00 66.08  ?  6921 LYS   B HE3    1 
ATOM   1934 H  HZ1    . LYS   A  1 123 ? 62.180  -13.810 -10.891 1.00 92.71  ?  6921 LYS   B HZ1    1 
ATOM   1935 H  HZ2    . LYS   A  1 123 ? 62.587  -14.998 -11.612 1.00 92.71  ?  6921 LYS   B HZ2    1 
ATOM   1936 H  HZ3    . LYS   A  1 123 ? 63.313  -14.585 -10.428 1.00 92.71  ?  6921 LYS   B HZ3    1 
ATOM   1937 N  N      . TRP   A  1 124 ? 69.983  -15.434 -12.470 1.00 47.86  ?  6922 TRP   B N      1 
ATOM   1938 C  CA     . TRP   A  1 124 ? 71.164  -16.288 -12.488 1.00 42.34  ?  6922 TRP   B CA     1 
ATOM   1939 C  C      . TRP   A  1 124 ? 70.755  -17.749 -12.568 1.00 41.01  ?  6922 TRP   B C      1 
ATOM   1940 O  O      . TRP   A  1 124 ? 69.683  -18.137 -12.097 1.00 45.56  ?  6922 TRP   B O      1 
ATOM   1941 C  CB     . TRP   A  1 124 ? 72.021  -16.017 -11.251 1.00 44.18  ?  6922 TRP   B CB     1 
ATOM   1942 C  CG     . TRP   A  1 124 ? 72.432  -14.576 -11.236 1.00 45.23  ?  6922 TRP   B CG     1 
ATOM   1943 C  CD1    . TRP   A  1 124 ? 71.701  -13.521 -10.780 1.00 42.66  ?  6922 TRP   B CD1    1 
ATOM   1944 C  CD2    . TRP   A  1 124 ? 73.632  -14.019 -11.790 1.00 42.71  ?  6922 TRP   B CD2    1 
ATOM   1945 N  NE1    . TRP   A  1 124 ? 72.385  -12.347 -10.976 1.00 45.60  ?  6922 TRP   B NE1    1 
ATOM   1946 C  CE2    . TRP   A  1 124 ? 73.572  -12.626 -11.604 1.00 43.76  ?  6922 TRP   B CE2    1 
ATOM   1947 C  CE3    . TRP   A  1 124 ? 74.750  -14.567 -12.414 1.00 42.64  ?  6922 TRP   B CE3    1 
ATOM   1948 C  CZ2    . TRP   A  1 124 ? 74.597  -11.779 -12.006 1.00 42.66  ?  6922 TRP   B CZ2    1 
ATOM   1949 C  CZ3    . TRP   A  1 124 ? 75.759  -13.732 -12.815 1.00 39.82  ?  6922 TRP   B CZ3    1 
ATOM   1950 C  CH2    . TRP   A  1 124 ? 75.678  -12.349 -12.614 1.00 37.56  ?  6922 TRP   B CH2    1 
ATOM   1951 H  H      . TRP   A  1 124 ? 69.426  -15.629 -11.844 1.00 57.95  ?  6922 TRP   B H      1 
ATOM   1952 H  HA     . TRP   A  1 124 ? 71.702  -16.111 -13.275 1.00 51.33  ?  6922 TRP   B HA     1 
ATOM   1953 H  HB2    . TRP   A  1 124 ? 71.509  -16.206 -10.449 1.00 53.54  ?  6922 TRP   B HB2    1 
ATOM   1954 H  HB3    . TRP   A  1 124 ? 72.817  -16.571 -11.275 1.00 53.54  ?  6922 TRP   B HB3    1 
ATOM   1955 H  HD1    . TRP   A  1 124 ? 70.859  -13.587 -10.391 1.00 51.71  ?  6922 TRP   B HD1    1 
ATOM   1956 H  HE1    . TRP   A  1 124 ? 72.114  -11.565 -10.743 1.00 55.24  ?  6922 TRP   B HE1    1 
ATOM   1957 H  HE3    . TRP   A  1 124 ? 74.810  -15.485 -12.557 1.00 51.69  ?  6922 TRP   B HE3    1 
ATOM   1958 H  HZ2    . TRP   A  1 124 ? 74.549  -10.860 -11.867 1.00 51.71  ?  6922 TRP   B HZ2    1 
ATOM   1959 H  HZ3    . TRP   A  1 124 ? 76.512  -14.090 -13.227 1.00 48.31  ?  6922 TRP   B HZ3    1 
ATOM   1960 H  HH2    . TRP   A  1 124 ? 76.376  -11.806 -12.902 1.00 45.60  ?  6922 TRP   B HH2    1 
ATOM   1961 N  N      . ASP   A  1 125 ? 71.603  -18.544 -13.211 1.00 45.13  ?  6923 ASP   B N      1 
ATOM   1962 C  CA     . ASP   A  1 125 ? 71.351  -19.968 -13.337 1.00 43.37  ?  6923 ASP   B CA     1 
ATOM   1963 C  C      . ASP   A  1 125 ? 71.976  -20.774 -12.210 1.00 40.77  ?  6923 ASP   B C      1 
ATOM   1964 O  O      . ASP   A  1 125 ? 71.557  -21.911 -11.979 1.00 40.99  ?  6923 ASP   B O      1 
ATOM   1965 C  CB     . ASP   A  1 125 ? 71.879  -20.482 -14.678 1.00 44.04  ?  6923 ASP   B CB     1 
ATOM   1966 C  CG     . ASP   A  1 125 ? 71.343  -19.690 -15.850 1.00 47.95  ?  6923 ASP   B CG     1 
ATOM   1967 O  OD1    . ASP   A  1 125 ? 70.168  -19.272 -15.820 1.00 46.13  ?  6923 ASP   B OD1    1 
ATOM   1968 O  OD2    . ASP   A  1 125 ? 72.105  -19.471 -16.806 1.00 43.70  ?  6923 ASP   B OD2    1 
ATOM   1969 H  H      . ASP   A  1 125 ? 72.332  -18.279 -13.582 1.00 54.68  ?  6923 ASP   B H      1 
ATOM   1970 H  HA     . ASP   A  1 125 ? 70.393  -20.121 -13.321 1.00 52.56  ?  6923 ASP   B HA     1 
ATOM   1971 H  HB2    . ASP   A  1 125 ? 72.847  -20.414 -14.685 1.00 53.38  ?  6923 ASP   B HB2    1 
ATOM   1972 H  HB3    . ASP   A  1 125 ? 71.611  -21.407 -14.792 1.00 53.38  ?  6923 ASP   B HB3    1 
ATOM   1973 N  N      . LEU   A  1 126 ? 72.935  -20.207 -11.484 1.00 44.13  ?  6924 LEU   B N      1 
ATOM   1974 C  CA     . LEU   A  1 126 ? 73.644  -20.958 -10.460 1.00 39.52  ?  6924 LEU   B CA     1 
ATOM   1975 C  C      . LEU   A  1 126 ? 74.275  -19.983 -9.483  1.00 40.85  ?  6924 LEU   B C      1 
ATOM   1976 O  O      . LEU   A  1 126 ? 74.964  -19.043 -9.898  1.00 43.31  ?  6924 LEU   B O      1 
ATOM   1977 C  CB     . LEU   A  1 126 ? 74.696  -21.876 -11.091 1.00 40.53  ?  6924 LEU   B CB     1 
ATOM   1978 C  CG     . LEU   A  1 126 ? 75.550  -22.670 -10.110 1.00 43.71  ?  6924 LEU   B CG     1 
ATOM   1979 C  CD1    . LEU   A  1 126 ? 74.599  -23.691 -9.506  1.00 44.43  ?  6924 LEU   B CD1    1 
ATOM   1980 C  CD2    . LEU   A  1 126 ? 76.689  -23.342 -10.784 1.00 40.28  ?  6924 LEU   B CD2    1 
ATOM   1981 H  H      . LEU   A  1 126 ? 73.191  -19.390 -11.566 1.00 53.48  ?  6924 LEU   B H      1 
ATOM   1982 H  HA     . LEU   A  1 126 ? 73.021  -21.511 -9.963  1.00 47.95  ?  6924 LEU   B HA     1 
ATOM   1983 H  HB2    . LEU   A  1 126 ? 74.239  -22.516 -11.660 1.00 49.15  ?  6924 LEU   B HB2    1 
ATOM   1984 H  HB3    . LEU   A  1 126 ? 75.297  -21.330 -11.622 1.00 49.15  ?  6924 LEU   B HB3    1 
ATOM   1985 H  HG     . LEU   A  1 126 ? 75.954  -22.100 -9.436  1.00 52.98  ?  6924 LEU   B HG     1 
ATOM   1986 H  HD11   . LEU   A  1 126 ? 75.115  -24.426 -9.139  1.00 53.83  ?  6924 LEU   B HD11   1 
ATOM   1987 H  HD12   . LEU   A  1 126 ? 74.082  -23.266 -8.804  1.00 53.83  ?  6924 LEU   B HD12   1 
ATOM   1988 H  HD13   . LEU   A  1 126 ? 74.006  -24.019 -10.201 1.00 53.83  ?  6924 LEU   B HD13   1 
ATOM   1989 H  HD21   . LEU   A  1 126 ? 77.207  -23.826 -10.122 1.00 48.86  ?  6924 LEU   B HD21   1 
ATOM   1990 H  HD22   . LEU   A  1 126 ? 76.343  -23.959 -11.449 1.00 48.86  ?  6924 LEU   B HD22   1 
ATOM   1991 H  HD23   . LEU   A  1 126 ? 77.243  -22.672 -11.212 1.00 48.86  ?  6924 LEU   B HD23   1 
ATOM   1992 N  N      . ILE   A  1 127 ? 74.026  -20.204 -8.194  1.00 41.28  ?  6925 ILE   B N      1 
ATOM   1993 C  CA     . ILE   A  1 127 ? 74.547  -19.365 -7.124  1.00 41.37  ?  6925 ILE   B CA     1 
ATOM   1994 C  C      . ILE   A  1 127 ? 75.402  -20.218 -6.196  1.00 33.71  ?  6925 ILE   B C      1 
ATOM   1995 O  O      . ILE   A  1 127 ? 74.933  -21.227 -5.662  1.00 39.85  ?  6925 ILE   B O      1 
ATOM   1996 C  CB     . ILE   A  1 127 ? 73.423  -18.684 -6.323  1.00 39.64  ?  6925 ILE   B CB     1 
ATOM   1997 C  CG1    . ILE   A  1 127 ? 72.535  -17.814 -7.207  1.00 39.66  ?  6925 ILE   B CG1    1 
ATOM   1998 C  CG2    . ILE   A  1 127 ? 74.022  -17.831 -5.205  1.00 39.03  ?  6925 ILE   B CG2    1 
ATOM   1999 C  CD1    . ILE   A  1 127 ? 71.241  -17.404 -6.520  1.00 42.01  ?  6925 ILE   B CD1    1 
ATOM   2000 H  H      . ILE   A  1 127 ? 73.541  -20.855 -7.909  1.00 50.06  ?  6925 ILE   B H      1 
ATOM   2001 H  HA     . ILE   A  1 127 ? 75.108  -18.681 -7.522  1.00 50.16  ?  6925 ILE   B HA     1 
ATOM   2002 H  HB     . ILE   A  1 127 ? 72.872  -19.389 -5.948  1.00 48.09  ?  6925 ILE   B HB     1 
ATOM   2003 H  HG12   . ILE   A  1 127 ? 73.018  -17.007 -7.444  1.00 48.11  ?  6925 ILE   B HG12   1 
ATOM   2004 H  HG13   . ILE   A  1 127 ? 72.305  -18.310 -8.009  1.00 48.11  ?  6925 ILE   B HG13   1 
ATOM   2005 H  HG21   . ILE   A  1 127 ? 73.326  -17.270 -4.829  1.00 47.36  ?  6925 ILE   B HG21   1 
ATOM   2006 H  HG22   . ILE   A  1 127 ? 74.381  -18.416 -4.519  1.00 47.36  ?  6925 ILE   B HG22   1 
ATOM   2007 H  HG23   . ILE   A  1 127 ? 74.729  -17.279 -5.573  1.00 47.36  ?  6925 ILE   B HG23   1 
ATOM   2008 H  HD11   . ILE   A  1 127 ? 70.653  -16.993 -7.173  1.00 50.93  ?  6925 ILE   B HD11   1 
ATOM   2009 H  HD12   . ILE   A  1 127 ? 70.819  -18.192 -6.145  1.00 50.93  ?  6925 ILE   B HD12   1 
ATOM   2010 H  HD13   . ILE   A  1 127 ? 71.445  -16.770 -5.814  1.00 50.93  ?  6925 ILE   B HD13   1 
ATOM   2011 N  N      . ILE   A  1 128 ? 76.646  -19.798 -6.001  1.00 35.99  ?  6926 ILE   B N      1 
ATOM   2012 C  CA     . ILE   A  1 128 ? 77.590  -20.415 -5.077  1.00 39.57  ?  6926 ILE   B CA     1 
ATOM   2013 C  C      . ILE   A  1 128 ? 77.909  -19.414 -3.978  1.00 38.97  ?  6926 ILE   B C      1 
ATOM   2014 O  O      . ILE   A  1 128 ? 78.168  -18.243 -4.264  1.00 42.89  ?  6926 ILE   B O      1 
ATOM   2015 C  CB     . ILE   A  1 128 ? 78.889  -20.822 -5.800  1.00 36.53  ?  6926 ILE   B CB     1 
ATOM   2016 C  CG1    . ILE   A  1 128 ? 78.603  -21.571 -7.107  1.00 42.74  ?  6926 ILE   B CG1    1 
ATOM   2017 C  CG2    . ILE   A  1 128 ? 79.755  -21.705 -4.847  1.00 42.11  ?  6926 ILE   B CG2    1 
ATOM   2018 C  CD1    . ILE   A  1 128 ? 77.903  -22.911 -6.909  1.00 40.43  ?  6926 ILE   B CD1    1 
ATOM   2019 H  H      . ILE   A  1 128 ? 76.983  -19.123 -6.414  1.00 43.71  ?  6926 ILE   B H      1 
ATOM   2020 H  HA     . ILE   A  1 128 ? 77.181  -21.199 -4.680  1.00 48.00  ?  6926 ILE   B HA     1 
ATOM   2021 H  HB     . ILE   A  1 128 ? 79.371  -20.013 -6.031  1.00 44.36  ?  6926 ILE   B HB     1 
ATOM   2022 H  HG12   . ILE   A  1 128 ? 78.033  -21.018 -7.664  1.00 51.81  ?  6926 ILE   B HG12   1 
ATOM   2023 H  HG13   . ILE   A  1 128 ? 79.445  -21.741 -7.559  1.00 51.81  ?  6926 ILE   B HG13   1 
ATOM   2024 H  HG21   . ILE   A  1 128 ? 80.504  -22.068 -5.347  1.00 51.06  ?  6926 ILE   B HG21   1 
ATOM   2025 H  HG22   . ILE   A  1 128 ? 80.081  -21.157 -4.117  1.00 51.06  ?  6926 ILE   B HG22   1 
ATOM   2026 H  HG23   . ILE   A  1 128 ? 79.208  -22.427 -4.501  1.00 51.06  ?  6926 ILE   B HG23   1 
ATOM   2027 H  HD11   . ILE   A  1 128 ? 77.665  -23.275 -7.776  1.00 49.04  ?  6926 ILE   B HD11   1 
ATOM   2028 H  HD12   . ILE   A  1 128 ? 78.505  -23.517 -6.450  1.00 49.04  ?  6926 ILE   B HD12   1 
ATOM   2029 H  HD13   . ILE   A  1 128 ? 77.103  -22.774 -6.378  1.00 49.04  ?  6926 ILE   B HD13   1 
ATOM   2030 N  N      . SER   A  1 129 ? 77.918  -19.870 -2.725  1.00 42.89  ?  6927 SER   B N      1 
ATOM   2031 C  CA     . SER   A  1 129 ? 78.344  -19.022 -1.617  1.00 37.22  ?  6927 SER   B CA     1 
ATOM   2032 C  C      . SER   A  1 129 ? 79.266  -19.789 -0.683  1.00 37.81  ?  6927 SER   B C      1 
ATOM   2033 O  O      . SER   A  1 129 ? 78.925  -20.890 -0.229  1.00 42.39  ?  6927 SER   B O      1 
ATOM   2034 C  CB     . SER   A  1 129 ? 77.146  -18.478 -0.827  1.00 36.00  ?  6927 SER   B CB     1 
ATOM   2035 O  OG     . SER   A  1 129 ? 77.570  -17.983 0.437   1.00 42.67  ?  6927 SER   B OG     1 
ATOM   2036 H  H      . SER   A  1 129 ? 77.681  -20.665 -2.495  1.00 51.99  ?  6927 SER   B H      1 
ATOM   2037 H  HA     . SER   A  1 129 ? 78.844  -18.276 -1.983  1.00 45.19  ?  6927 SER   B HA     1 
ATOM   2038 H  HB2    . SER   A  1 129 ? 76.736  -17.757 -1.329  1.00 43.73  ?  6927 SER   B HB2    1 
ATOM   2039 H  HB3    . SER   A  1 129 ? 76.506  -19.194 -0.689  1.00 43.73  ?  6927 SER   B HB3    1 
ATOM   2040 H  HG     . SER   A  1 129 ? 77.683  -18.621 0.972   1.00 51.72  ?  6927 SER   B HG     1 
ATOM   2041 N  N      . ASP   A  1 130 ? 80.437  -19.205 -0.411  1.00 41.84  ?  6928 ASP   B N      1 
ATOM   2042 C  CA     . ASP   A  1 130 ? 81.329  -19.668 0.643   1.00 47.69  ?  6928 ASP   B CA     1 
ATOM   2043 C  C      . ASP   A  1 130 ? 81.455  -18.593 1.720   1.00 39.16  ?  6928 ASP   B C      1 
ATOM   2044 O  O      . ASP   A  1 130 ? 82.464  -18.525 2.416   1.00 44.22  ?  6928 ASP   B O      1 
ATOM   2045 C  CB     . ASP   A  1 130 ? 82.695  -20.034 0.060   1.00 41.00  ?  6928 ASP   B CB     1 
ATOM   2046 C  CG     . ASP   A  1 130 ? 83.523  -20.873 1.004   1.00 41.85  ?  6928 ASP   B CG     1 
ATOM   2047 O  OD1    . ASP   A  1 130 ? 84.737  -20.681 1.093   1.00 48.07  ?  6928 ASP   B OD1    1 
ATOM   2048 O  OD2    . ASP   A  1 130 ? 82.953  -21.752 1.692   1.00 51.07  ?  6928 ASP   B OD2    1 
ATOM   2049 H  H      . ASP   A  1 130 ? 80.740  -18.522 -0.836  1.00 50.73  ?  6928 ASP   B H      1 
ATOM   2050 H  HA     . ASP   A  1 130 ? 80.980  -20.474 1.053   1.00 57.75  ?  6928 ASP   B HA     1 
ATOM   2051 H  HB2    . ASP   A  1 130 ? 82.565  -20.541 -0.757  1.00 49.72  ?  6928 ASP   B HB2    1 
ATOM   2052 H  HB3    . ASP   A  1 130 ? 83.187  -19.220 -0.130  1.00 49.72  ?  6928 ASP   B HB3    1 
ATOM   2053 N  N      . MET   A  1 131 ? 80.457  -17.708 1.808   1.00 41.97  ?  6929 MET   B N      1 
ATOM   2054 C  CA     . MET   A  1 131 ? 80.419  -16.684 2.844   1.00 43.50  ?  6929 MET   B CA     1 
ATOM   2055 C  C      . MET   A  1 131 ? 80.400  -17.344 4.205   1.00 40.07  ?  6929 MET   B C      1 
ATOM   2056 O  O      . MET   A  1 131 ? 79.679  -18.318 4.428   1.00 39.60  ?  6929 MET   B O      1 
ATOM   2057 C  CB     . MET   A  1 131 ? 79.194  -15.794 2.638   1.00 42.70  ?  6929 MET   B CB     1 
ATOM   2058 C  CG     . MET   A  1 131 ? 79.491  -14.642 1.701   1.00 43.08  ?  6929 MET   B CG     1 
ATOM   2059 S  SD     . MET   A  1 131 ? 78.169  -13.461 1.419   1.00 39.98  ?  6929 MET   B SD     1 
ATOM   2060 C  CE     . MET   A  1 131 ? 76.738  -14.509 1.231   1.00 34.70  ?  6929 MET   B CE     1 
ATOM   2061 H  H      . MET   A  1 131 ? 79.785  -17.682 1.273   1.00 50.89  ?  6929 MET   B H      1 
ATOM   2062 H  HA     . MET   A  1 131 ? 81.201  -16.113 2.785   1.00 52.72  ?  6929 MET   B HA     1 
ATOM   2063 H  HB2    . MET   A  1 131 ? 78.476  -16.322 2.255   1.00 51.76  ?  6929 MET   B HB2    1 
ATOM   2064 H  HB3    . MET   A  1 131 ? 78.917  -15.428 3.493   1.00 51.76  ?  6929 MET   B HB3    1 
ATOM   2065 H  HG2    . MET   A  1 131 ? 80.240  -14.145 2.065   1.00 52.22  ?  6929 MET   B HG2    1 
ATOM   2066 H  HG3    . MET   A  1 131 ? 79.727  -15.013 0.836   1.00 52.22  ?  6929 MET   B HG3    1 
ATOM   2067 H  HE1    . MET   A  1 131 ? 75.961  -13.955 1.055   1.00 42.16  ?  6929 MET   B HE1    1 
ATOM   2068 H  HE2    . MET   A  1 131 ? 76.886  -15.116 0.488   1.00 42.16  ?  6929 MET   B HE2    1 
ATOM   2069 H  HE3    . MET   A  1 131 ? 76.606  -15.013 2.049   1.00 42.16  ?  6929 MET   B HE3    1 
ATOM   2070 N  N      . TYR   A  1 132 ? 81.236  -16.835 5.099   1.00 43.86  ?  6930 TYR   B N      1 
ATOM   2071 C  CA     . TYR   A  1 132 ? 81.414  -17.444 6.401   1.00 43.80  ?  6930 TYR   B CA     1 
ATOM   2072 C  C      . TYR   A  1 132 ? 82.124  -16.461 7.323   1.00 41.14  ?  6930 TYR   B C      1 
ATOM   2073 O  O      . TYR   A  1 132 ? 83.173  -15.912 6.977   1.00 48.48  ?  6930 TYR   B O      1 
ATOM   2074 C  CB     . TYR   A  1 132 ? 82.173  -18.764 6.265   1.00 47.08  ?  6930 TYR   B CB     1 
ATOM   2075 C  CG     . TYR   A  1 132 ? 82.460  -19.386 7.602   1.00 44.65  ?  6930 TYR   B CG     1 
ATOM   2076 C  CD1    . TYR   A  1 132 ? 81.419  -19.868 8.390   1.00 44.33  ?  6930 TYR   B CD1    1 
ATOM   2077 C  CD2    . TYR   A  1 132 ? 83.760  -19.481 8.093   1.00 44.75  ?  6930 TYR   B CD2    1 
ATOM   2078 C  CE1    . TYR   A  1 132 ? 81.653  -20.423 9.627   1.00 45.15  ?  6930 TYR   B CE1    1 
ATOM   2079 C  CE2    . TYR   A  1 132 ? 84.002  -20.047 9.332   1.00 48.56  ?  6930 TYR   B CE2    1 
ATOM   2080 C  CZ     . TYR   A  1 132 ? 82.939  -20.508 10.089  1.00 48.40  ?  6930 TYR   B CZ     1 
ATOM   2081 O  OH     . TYR   A  1 132 ? 83.176  -21.058 11.317  1.00 56.78  ?  6930 TYR   B OH     1 
ATOM   2082 H  H      . TYR   A  1 132 ? 81.715  -16.131 4.972   1.00 53.15  ?  6930 TYR   B H      1 
ATOM   2083 H  HA     . TYR   A  1 132 ? 80.558  -17.661 6.804   1.00 53.08  ?  6930 TYR   B HA     1 
ATOM   2084 H  HB2    . TYR   A  1 132 ? 81.638  -19.388 5.748   1.00 57.02  ?  6930 TYR   B HB2    1 
ATOM   2085 H  HB3    . TYR   A  1 132 ? 83.018  -18.602 5.817   1.00 57.02  ?  6930 TYR   B HB3    1 
ATOM   2086 H  HD1    . TYR   A  1 132 ? 80.546  -19.813 8.074   1.00 53.71  ?  6930 TYR   B HD1    1 
ATOM   2087 H  HD2    . TYR   A  1 132 ? 84.470  -19.162 7.584   1.00 54.23  ?  6930 TYR   B HD2    1 
ATOM   2088 H  HE1    . TYR   A  1 132 ? 80.945  -20.737 10.143  1.00 54.71  ?  6930 TYR   B HE1    1 
ATOM   2089 H  HE2    . TYR   A  1 132 ? 84.871  -20.118 9.653   1.00 58.79  ?  6930 TYR   B HE2    1 
ATOM   2090 H  HH     . TYR   A  1 132 ? 83.999  -21.042 11.485  1.00 68.65  ?  6930 TYR   B HH     1 
ATOM   2091 N  N      . ASP   A  1 133 ? 81.523  -16.196 8.474   1.00 46.22  ?  6931 ASP   B N      1 
ATOM   2092 C  CA     . ASP   A  1 133 ? 82.159  -15.427 9.528   1.00 50.64  ?  6931 ASP   B CA     1 
ATOM   2093 C  C      . ASP   A  1 133 ? 82.641  -16.374 10.609  1.00 55.01  ?  6931 ASP   B C      1 
ATOM   2094 O  O      . ASP   A  1 133 ? 81.808  -16.931 11.345  1.00 57.82  ?  6931 ASP   B O      1 
ATOM   2095 C  CB     . ASP   A  1 133 ? 81.184  -14.413 10.111  1.00 57.84  ?  6931 ASP   B CB     1 
ATOM   2096 C  CG     . ASP   A  1 133 ? 81.857  -13.448 11.057  1.00 66.03  ?  6931 ASP   B CG     1 
ATOM   2097 O  OD1    . ASP   A  1 133 ? 82.807  -13.871 11.751  1.00 67.29  ?  6931 ASP   B OD1    1 
ATOM   2098 O  OD2    . ASP   A  1 133 ? 81.440  -12.275 11.126  1.00 75.05  ?  6931 ASP   B OD2    1 
ATOM   2099 H  H      . ASP   A  1 133 ? 80.728  -16.458 8.672   1.00 55.98  ?  6931 ASP   B H      1 
ATOM   2100 H  HA     . ASP   A  1 133 ? 82.923  -14.952 9.166   1.00 61.30  ?  6931 ASP   B HA     1 
ATOM   2101 H  HB2    . ASP   A  1 133 ? 80.788  -13.901 9.388   1.00 69.93  ?  6931 ASP   B HB2    1 
ATOM   2102 H  HB3    . ASP   A  1 133 ? 80.492  -14.883 10.602  1.00 69.93  ?  6931 ASP   B HB3    1 
ATOM   2103 N  N      . PRO   A  1 134 ? 83.953  -16.574 10.771  1.00 63.93  ?  6932 PRO   B N      1 
ATOM   2104 C  CA     . PRO   A  1 134 ? 84.422  -17.605 11.716  1.00 71.43  ?  6932 PRO   B CA     1 
ATOM   2105 C  C      . PRO   A  1 134 ? 84.164  -17.262 13.176  1.00 70.31  ?  6932 PRO   B C      1 
ATOM   2106 O  O      . PRO   A  1 134 ? 84.334  -18.134 14.037  1.00 71.55  ?  6932 PRO   B O      1 
ATOM   2107 C  CB     . PRO   A  1 134 ? 85.923  -17.697 11.419  1.00 64.01  ?  6932 PRO   B CB     1 
ATOM   2108 C  CG     . PRO   A  1 134 ? 86.281  -16.344 10.858  1.00 69.18  ?  6932 PRO   B CG     1 
ATOM   2109 C  CD     . PRO   A  1 134 ? 85.067  -15.814 10.171  1.00 64.71  ?  6932 PRO   B CD     1 
ATOM   2110 H  HA     . PRO   A  1 134 ? 84.007  -18.458 11.514  1.00 86.24  ?  6932 PRO   B HA     1 
ATOM   2111 H  HB2    . PRO   A  1 134 ? 86.413  -17.876 12.237  1.00 77.34  ?  6932 PRO   B HB2    1 
ATOM   2112 H  HB3    . PRO   A  1 134 ? 86.090  -18.399 10.771  1.00 77.34  ?  6932 PRO   B HB3    1 
ATOM   2113 H  HG2    . PRO   A  1 134 ? 86.544  -15.755 11.582  1.00 83.54  ?  6932 PRO   B HG2    1 
ATOM   2114 H  HG3    . PRO   A  1 134 ? 87.011  -16.441 10.226  1.00 83.54  ?  6932 PRO   B HG3    1 
ATOM   2115 H  HD2    . PRO   A  1 134 ? 84.964  -14.864 10.343  1.00 78.17  ?  6932 PRO   B HD2    1 
ATOM   2116 H  HD3    . PRO   A  1 134 ? 85.116  -15.975 9.216   1.00 78.17  ?  6932 PRO   B HD3    1 
ATOM   2117 N  N      . LYS   A  1 135 ? 83.747  -16.032 13.475  1.00 69.76  ?  6933 LYS   B N      1 
ATOM   2118 C  CA     . LYS   A  1 135 ? 83.371  -15.654 14.826  1.00 75.39  ?  6933 LYS   B CA     1 
ATOM   2119 C  C      . LYS   A  1 135 ? 82.111  -16.376 15.287  1.00 74.81  ?  6933 LYS   B C      1 
ATOM   2120 O  O      . LYS   A  1 135 ? 81.771  -16.295 16.472  1.00 83.42  ?  6933 LYS   B O      1 
ATOM   2121 C  CB     . LYS   A  1 135 ? 83.179  -14.131 14.893  1.00 76.15  ?  6933 LYS   B CB     1 
ATOM   2122 C  CG     . LYS   A  1 135 ? 84.461  -13.312 14.825  1.00 80.25  ?  6933 LYS   B CG     1 
ATOM   2123 C  CD     . LYS   A  1 135 ? 84.232  -11.796 14.799  1.00 93.80  ?  6933 LYS   B CD     1 
ATOM   2124 C  CE     . LYS   A  1 135 ? 82.969  -11.380 14.074  1.00 89.60  ?  6933 LYS   B CE     1 
ATOM   2125 N  NZ     . LYS   A  1 135 ? 83.135  -10.201 13.141  1.00 82.71  ?  6933 LYS   B NZ     1 
ATOM   2126 H  H      . LYS   A  1 135 ? 83.673  -15.393 12.903  1.00 84.23  ?  6933 LYS   B H      1 
ATOM   2127 H  HA     . LYS   A  1 135 ? 84.081  -15.885 15.445  1.00 91.00  ?  6933 LYS   B HA     1 
ATOM   2128 H  HB2    . LYS   A  1 135 ? 82.622  -13.860 14.147  1.00 91.90  ?  6933 LYS   B HB2    1 
ATOM   2129 H  HB3    . LYS   A  1 135 ? 82.740  -13.915 15.731  1.00 91.90  ?  6933 LYS   B HB3    1 
ATOM   2130 H  HG2    . LYS   A  1 135 ? 85.002  -13.514 15.605  1.00 96.82  ?  6933 LYS   B HG2    1 
ATOM   2131 H  HG3    . LYS   A  1 135 ? 84.941  -13.551 14.017  1.00 96.82  ?  6933 LYS   B HG3    1 
ATOM   2132 H  HD2    . LYS   A  1 135 ? 84.167  -11.474 15.712  1.00 113.09 ?  6933 LYS   B HD2    1 
ATOM   2133 H  HD3    . LYS   A  1 135 ? 84.981  -11.374 14.351  1.00 113.09 ?  6933 LYS   B HD3    1 
ATOM   2134 H  HE2    . LYS   A  1 135 ? 82.656  -12.129 13.544  1.00 108.04 ?  6933 LYS   B HE2    1 
ATOM   2135 H  HE3    . LYS   A  1 135 ? 82.300  -11.137 14.734  1.00 108.04 ?  6933 LYS   B HE3    1 
ATOM   2136 H  HZ1    . LYS   A  1 135 ? 82.360  -10.017 12.742  1.00 99.78  ?  6933 LYS   B HZ1    1 
ATOM   2137 H  HZ2    . LYS   A  1 135 ? 83.400  -9.485  13.598  1.00 99.78  ?  6933 LYS   B HZ2    1 
ATOM   2138 H  HZ3    . LYS   A  1 135 ? 83.743  -10.388 12.519  1.00 99.78  ?  6933 LYS   B HZ3    1 
ATOM   2139 N  N      . THR   A  1 136 ? 81.423  -17.098 14.395  1.00 69.77  ?  6934 THR   B N      1 
ATOM   2140 C  CA     . THR   A  1 136 ? 80.185  -17.758 14.792  1.00 76.37  ?  6934 THR   B CA     1 
ATOM   2141 C  C      . THR   A  1 136 ? 80.415  -19.048 15.570  1.00 72.87  ?  6934 THR   B C      1 
ATOM   2142 O  O      . THR   A  1 136 ? 79.508  -19.467 16.298  1.00 70.69  ?  6934 THR   B O      1 
ATOM   2143 C  CB     . THR   A  1 136 ? 79.299  -18.080 13.577  1.00 59.38  ?  6934 THR   B CB     1 
ATOM   2144 O  OG1    . THR   A  1 136 ? 80.016  -18.915 12.656  1.00 58.95  ?  6934 THR   B OG1    1 
ATOM   2145 C  CG2    . THR   A  1 136 ? 78.825  -16.819 12.870  1.00 55.27  ?  6934 THR   B CG2    1 
ATOM   2146 H  H      . THR   A  1 136 ? 81.650  -17.216 13.574  1.00 84.25  ?  6934 THR   B H      1 
ATOM   2147 H  HA     . THR   A  1 136 ? 79.703  -17.132 15.355  1.00 92.17  ?  6934 THR   B HA     1 
ATOM   2148 H  HB     . THR   A  1 136 ? 78.510  -18.549 13.888  1.00 71.78  ?  6934 THR   B HB     1 
ATOM   2149 H  HG1    . THR   A  1 136 ? 80.723  -18.534 12.412  1.00 71.26  ?  6934 THR   B HG1    1 
ATOM   2150 H  HG21   . THR   A  1 136 ? 78.181  -17.047 12.181  1.00 66.85  ?  6934 THR   B HG21   1 
ATOM   2151 H  HG22   . THR   A  1 136 ? 78.405  -16.220 13.507  1.00 66.85  ?  6934 THR   B HG22   1 
ATOM   2152 H  HG23   . THR   A  1 136 ? 79.577  -16.365 12.459  1.00 66.85  ?  6934 THR   B HG23   1 
ATOM   2153 N  N      . LYS   A  1 137 ? 81.586  -19.689 15.452  1.00 66.37  ?  6935 LYS   B N      1 
ATOM   2154 C  CA     . LYS   A  1 137 ? 81.785  -20.984 16.114  1.00 80.46  ?  6935 LYS   B CA     1 
ATOM   2155 C  C      . LYS   A  1 137 ? 82.080  -20.841 17.604  1.00 97.66  ?  6935 LYS   B C      1 
ATOM   2156 O  O      . LYS   A  1 137 ? 82.945  -21.521 18.163  1.00 102.53 ?  6935 LYS   B O      1 
ATOM   2157 C  CB     . LYS   A  1 137 ? 82.896  -21.796 15.445  1.00 78.21  ?  6935 LYS   B CB     1 
ATOM   2158 C  CG     . LYS   A  1 137 ? 84.312  -21.280 15.563  1.00 79.03  ?  6935 LYS   B CG     1 
ATOM   2159 C  CD     . LYS   A  1 137 ? 85.321  -22.468 15.532  1.00 105.00 ?  6935 LYS   B CD     1 
ATOM   2160 C  CE     . LYS   A  1 137 ? 85.057  -23.447 14.394  1.00 96.80  ?  6935 LYS   B CE     1 
ATOM   2161 N  NZ     . LYS   A  1 137 ? 86.151  -24.404 14.129  1.00 85.87  ?  6935 LYS   B NZ     1 
ATOM   2162 H  H      . LYS   A  1 137 ? 82.262  -19.401 15.006  1.00 80.16  ?  6935 LYS   B H      1 
ATOM   2163 H  HA     . LYS   A  1 137 ? 80.964  -21.486 15.996  1.00 97.08  ?  6935 LYS   B HA     1 
ATOM   2164 H  HB2    . LYS   A  1 137 ? 82.889  -22.684 15.834  1.00 94.37  ?  6935 LYS   B HB2    1 
ATOM   2165 H  HB3    . LYS   A  1 137 ? 82.696  -21.847 14.497  1.00 94.37  ?  6935 LYS   B HB3    1 
ATOM   2166 H  HG2    . LYS   A  1 137 ? 84.506  -20.688 14.820  1.00 95.36  ?  6935 LYS   B HG2    1 
ATOM   2167 H  HG3    . LYS   A  1 137 ? 84.417  -20.804 16.402  1.00 95.36  ?  6935 LYS   B HG3    1 
ATOM   2168 H  HD2    . LYS   A  1 137 ? 86.219  -22.117 15.421  1.00 126.52 ?  6935 LYS   B HD2    1 
ATOM   2169 H  HD3    . LYS   A  1 137 ? 85.258  -22.958 16.367  1.00 126.52 ?  6935 LYS   B HD3    1 
ATOM   2170 H  HE2    . LYS   A  1 137 ? 84.265  -23.963 14.609  1.00 116.68 ?  6935 LYS   B HE2    1 
ATOM   2171 H  HE3    . LYS   A  1 137 ? 84.911  -22.940 13.579  1.00 116.68 ?  6935 LYS   B HE3    1 
ATOM   2172 H  HZ1    . LYS   A  1 137 ? 86.054  -24.762 13.320  1.00 103.56 ?  6935 LYS   B HZ1    1 
ATOM   2173 H  HZ2    . LYS   A  1 137 ? 86.936  -23.986 14.168  1.00 103.56 ?  6935 LYS   B HZ2    1 
ATOM   2174 H  HZ3    . LYS   A  1 137 ? 86.140  -25.054 14.736  1.00 103.56 ?  6935 LYS   B HZ3    1 
ATOM   2175 N  N      . ASN   A  1 138 ? 81.373  -19.944 18.252  1.00 107.58 ?  6936 ASN   B N      1 
ATOM   2176 C  CA     . ASN   A  1 138 ? 81.569  -19.623 19.642  1.00 113.26 ?  6936 ASN   B CA     1 
ATOM   2177 C  C      . ASN   A  1 138 ? 80.715  -20.649 20.436  1.00 106.81 ?  6936 ASN   B C      1 
ATOM   2178 O  O      . ASN   A  1 138 ? 79.473  -20.650 20.381  1.00 86.66  ?  6936 ASN   B O      1 
ATOM   2179 C  CB     . ASN   A  1 138 ? 81.244  -18.129 19.797  1.00 107.98 ?  6936 ASN   B CB     1 
ATOM   2180 C  CG     . ASN   A  1 138 ? 82.005  -17.502 20.935  1.00 122.99 ?  6936 ASN   B CG     1 
ATOM   2181 O  OD1    . ASN   A  1 138 ? 82.396  -18.203 21.815  1.00 113.31 ?  6936 ASN   B OD1    1 
ATOM   2182 N  ND2    . ASN   A  1 138 ? 81.881  -16.164 21.070  1.00 127.21 ?  6936 ASN   B ND2    1 
ATOM   2183 H  H      . ASN   A  1 138 ? 80.743  -19.485 17.889  1.00 129.61 ?  6936 ASN   B H      1 
ATOM   2184 H  HA     . ASN   A  1 138 ? 82.467  -19.727 19.995  1.00 136.43 ?  6936 ASN   B HA     1 
ATOM   2185 H  HB2    . ASN   A  1 138 ? 81.483  -17.664 18.980  1.00 130.10 ?  6936 ASN   B HB2    1 
ATOM   2186 H  HB3    . ASN   A  1 138 ? 80.296  -18.025 19.973  1.00 130.10 ?  6936 ASN   B HB3    1 
ATOM   2187 H  HD21   . ASN   A  1 138 ? 82.295  -15.756 21.704  1.00 153.17 ?  6936 ASN   B HD21   1 
ATOM   2188 H  HD22   . ASN   A  1 138 ? 81.388  -15.720 20.523  1.00 153.17 ?  6936 ASN   B HD22   1 
ATOM   2189 N  N      . VAL   A  1 139 ? 81.412  -21.625 21.042  1.00 109.80 ?  6937 VAL   B N      1 
ATOM   2190 C  CA     . VAL   A  1 139 ? 80.804  -22.837 21.589  1.00 98.78  ?  6937 VAL   B CA     1 
ATOM   2191 C  C      . VAL   A  1 139 ? 80.221  -22.631 22.973  1.00 107.93 ?  6937 VAL   B C      1 
ATOM   2192 O  O      . VAL   A  1 139 ? 79.730  -23.597 23.573  1.00 92.31  ?  6937 VAL   B O      1 
ATOM   2193 C  CB     . VAL   A  1 139 ? 81.854  -23.968 21.629  1.00 98.68  ?  6937 VAL   B CB     1 
ATOM   2194 C  CG1    . VAL   A  1 139 ? 82.331  -24.321 20.211  1.00 93.30  ?  6937 VAL   B CG1    1 
ATOM   2195 C  CG2    . VAL   A  1 139 ? 83.044  -23.589 22.496  1.00 95.46  ?  6937 VAL   B CG2    1 
ATOM   2196 H  H      . VAL   A  1 139 ? 82.265  -21.604 21.149  1.00 132.28 ?  6937 VAL   B H      1 
ATOM   2197 H  HA     . VAL   A  1 139 ? 80.070  -23.104 21.014  1.00 119.06 ?  6937 VAL   B HA     1 
ATOM   2198 H  HB     . VAL   A  1 139 ? 81.432  -24.750 22.020  1.00 118.94 ?  6937 VAL   B HB     1 
ATOM   2199 H  HG11   . VAL   A  1 139 ? 82.966  -25.052 20.264  1.00 112.49 ?  6937 VAL   B HG11   1 
ATOM   2200 H  HG12   . VAL   A  1 139 ? 81.566  -24.585 19.677  1.00 112.49 ?  6937 VAL   B HG12   1 
ATOM   2201 H  HG13   . VAL   A  1 139 ? 82.755  -23.542 19.818  1.00 112.49 ?  6937 VAL   B HG13   1 
ATOM   2202 H  HG21   . VAL   A  1 139 ? 83.661  -24.338 22.531  1.00 115.07 ?  6937 VAL   B HG21   1 
ATOM   2203 H  HG22   . VAL   A  1 139 ? 83.484  -22.817 22.109  1.00 115.07 ?  6937 VAL   B HG22   1 
ATOM   2204 H  HG23   . VAL   A  1 139 ? 82.730  -23.378 23.390  1.00 115.07 ?  6937 VAL   B HG23   1 
ATOM   2205 N  N      . THR   A  1 140 ? 80.240  -21.405 23.487  1.00 120.53 ?  6938 THR   B N      1 
ATOM   2206 C  CA     . THR   A  1 140 ? 79.735  -21.114 24.815  1.00 116.07 ?  6938 THR   B CA     1 
ATOM   2207 C  C      . THR   A  1 140 ? 78.380  -20.424 24.836  1.00 108.34 ?  6938 THR   B C      1 
ATOM   2208 O  O      . THR   A  1 140 ? 77.856  -20.182 25.928  1.00 108.10 ?  6938 THR   B O      1 
ATOM   2209 C  CB     . THR   A  1 140 ? 80.772  -20.269 25.590  1.00 107.17 ?  6938 THR   B CB     1 
ATOM   2210 O  OG1    . THR   A  1 140 ? 80.712  -18.889 25.198  1.00 98.67  ?  6938 THR   B OG1    1 
ATOM   2211 C  CG2    . THR   A  1 140 ? 82.186  -20.804 25.388  1.00 88.24  ?  6938 THR   B CG2    1 
ATOM   2212 H  H      . THR   A  1 140 ? 80.546  -20.715 23.075  1.00 145.16 ?  6938 THR   B H      1 
ATOM   2213 H  HA     . THR   A  1 140 ? 79.616  -21.950 25.291  1.00 139.81 ?  6938 THR   B HA     1 
ATOM   2214 H  HB     . THR   A  1 140 ? 80.562  -20.327 26.535  1.00 129.13 ?  6938 THR   B HB     1 
ATOM   2215 H  HG1    . THR   A  1 140 ? 81.265  -18.440 25.643  1.00 118.93 ?  6938 THR   B HG1    1 
ATOM   2216 H  HG21   . THR   A  1 140 ? 82.806  -20.329 25.963  1.00 106.41 ?  6938 THR   B HG21   1 
ATOM   2217 H  HG22   . THR   A  1 140 ? 82.217  -21.749 25.603  1.00 106.41 ?  6938 THR   B HG22   1 
ATOM   2218 H  HG23   . THR   A  1 140 ? 82.458  -20.682 24.464  1.00 106.41 ?  6938 THR   B HG23   1 
ATOM   2219 N  N      . LYS   A  1 141 ? 77.814  -20.072 23.685  1.00 100.58 ?  6939 LYS   B N      1 
ATOM   2220 C  CA     . LYS   A  1 141 ? 76.464  -19.523 23.624  1.00 89.14  ?  6939 LYS   B CA     1 
ATOM   2221 C  C      . LYS   A  1 141 ? 75.582  -20.401 22.759  1.00 77.91  ?  6939 LYS   B C      1 
ATOM   2222 O  O      . LYS   A  1 141 ? 76.061  -21.214 21.966  1.00 74.97  ?  6939 LYS   B O      1 
ATOM   2223 C  CB     . LYS   A  1 141 ? 76.390  -18.069 23.101  1.00 91.59  ?  6939 LYS   B CB     1 
ATOM   2224 C  CG     . LYS   A  1 141 ? 77.057  -16.998 23.992  1.00 100.01 ?  6939 LYS   B CG     1 
ATOM   2225 C  CD     . LYS   A  1 141 ? 78.506  -17.296 24.087  1.00 104.59 ?  6939 LYS   B CD     1 
ATOM   2226 C  CE     . LYS   A  1 141 ? 79.128  -17.401 22.707  1.00 114.41 ?  6939 LYS   B CE     1 
ATOM   2227 N  NZ     . LYS   A  1 141 ? 80.264  -18.200 23.034  1.00 133.96 ?  6939 LYS   B NZ     1 
ATOM   2228 H  H      . LYS   A  1 141 ? 78.198  -20.142 22.918  1.00 121.22 ?  6939 LYS   B H      1 
ATOM   2229 H  HA     . LYS   A  1 141 ? 76.128  -19.512 24.534  1.00 107.48 ?  6939 LYS   B HA     1 
ATOM   2230 H  HB2    . LYS   A  1 141 ? 76.826  -18.035 22.235  1.00 110.43 ?  6939 LYS   B HB2    1 
ATOM   2231 H  HB3    . LYS   A  1 141 ? 75.455  -17.826 23.011  1.00 110.43 ?  6939 LYS   B HB3    1 
ATOM   2232 H  HG2    . LYS   A  1 141 ? 76.939  -16.119 23.600  1.00 120.54 ?  6939 LYS   B HG2    1 
ATOM   2233 H  HG3    . LYS   A  1 141 ? 76.671  -17.019 24.882  1.00 120.54 ?  6939 LYS   B HG3    1 
ATOM   2234 H  HD2    . LYS   A  1 141 ? 78.951  -16.584 24.572  1.00 126.02 ?  6939 LYS   B HD2    1 
ATOM   2235 H  HD3    . LYS   A  1 141 ? 78.633  -18.141 24.546  1.00 126.02 ?  6939 LYS   B HD3    1 
ATOM   2236 H  HE2    . LYS   A  1 141 ? 78.547  -17.852 22.075  1.00 137.81 ?  6939 LYS   B HE2    1 
ATOM   2237 H  HE3    . LYS   A  1 141 ? 79.392  -16.536 22.356  1.00 137.81 ?  6939 LYS   B HE3    1 
ATOM   2238 H  HZ1    . LYS   A  1 141 ? 80.563  -18.617 22.307  1.00 161.28 ?  6939 LYS   B HZ1    1 
ATOM   2239 H  HZ2    . LYS   A  1 141 ? 80.914  -17.687 23.361  1.00 161.28 ?  6939 LYS   B HZ2    1 
ATOM   2240 H  HZ3    . LYS   A  1 141 ? 80.043  -18.809 23.645  1.00 161.28 ?  6939 LYS   B HZ3    1 
ATOM   2241 N  N      . GLU   A  1 142 ? 74.277  -20.209 22.924  1.00 62.15  ?  6940 GLU   B N      1 
ATOM   2242 C  CA     . GLU   A  1 142 ? 73.308  -21.032 22.221  1.00 56.49  ?  6940 GLU   B CA     1 
ATOM   2243 C  C      . GLU   A  1 142 ? 73.461  -20.847 20.720  1.00 62.24  ?  6940 GLU   B C      1 
ATOM   2244 O  O      . GLU   A  1 142 ? 73.937  -19.814 20.242  1.00 64.31  ?  6940 GLU   B O      1 
ATOM   2245 C  CB     . GLU   A  1 142 ? 71.898  -20.684 22.681  1.00 55.00  ?  6940 GLU   B CB     1 
ATOM   2246 C  CG     . GLU   A  1 142 ? 70.819  -21.506 22.033  1.00 77.98  ?  6940 GLU   B CG     1 
ATOM   2247 C  CD     . GLU   A  1 142 ? 69.506  -21.299 22.698  1.00 95.62  ?  6940 GLU   B CD     1 
ATOM   2248 O  OE1    . GLU   A  1 142 ? 69.479  -20.675 23.770  1.00 86.82  ?  6940 GLU   B OE1    1 
ATOM   2249 O  OE2    . GLU   A  1 142 ? 68.493  -21.756 22.159  1.00 106.87 ?  6940 GLU   B OE2    1 
ATOM   2250 H  H      . GLU   A  1 142 ? 73.931  -19.611 23.435  1.00 75.10  ?  6940 GLU   B H      1 
ATOM   2251 H  HA     . GLU   A  1 142 ? 73.454  -21.970 22.420  1.00 68.31  ?  6940 GLU   B HA     1 
ATOM   2252 H  HB2    . GLU   A  1 142 ? 71.841  -20.826 23.639  1.00 66.52  ?  6940 GLU   B HB2    1 
ATOM   2253 H  HB3    . GLU   A  1 142 ? 71.725  -19.753 22.472  1.00 66.52  ?  6940 GLU   B HB3    1 
ATOM   2254 H  HG2    . GLU   A  1 142 ? 70.734  -21.248 21.102  1.00 94.10  ?  6940 GLU   B HG2    1 
ATOM   2255 H  HG3    . GLU   A  1 142 ? 71.049  -22.446 22.097  1.00 94.10  ?  6940 GLU   B HG3    1 
ATOM   2256 N  N      . ASN   A  1 143 ? 73.043  -21.857 19.974  1.00 50.95  ?  6941 ASN   B N      1 
ATOM   2257 C  CA     . ASN   A  1 143 ? 73.266  -21.897 18.536  1.00 52.88  ?  6941 ASN   B CA     1 
ATOM   2258 C  C      . ASN   A  1 143 ? 71.927  -21.639 17.856  1.00 48.90  ?  6941 ASN   B C      1 
ATOM   2259 O  O      . ASN   A  1 143 ? 71.165  -22.561 17.559  1.00 50.97  ?  6941 ASN   B O      1 
ATOM   2260 C  CB     . ASN   A  1 143 ? 73.847  -23.241 18.138  1.00 49.97  ?  6941 ASN   B CB     1 
ATOM   2261 C  CG     . ASN   A  1 143 ? 74.170  -23.311 16.674  1.00 43.80  ?  6941 ASN   B CG     1 
ATOM   2262 O  OD1    . ASN   A  1 143 ? 74.264  -22.270 16.010  1.00 45.96  ?  6941 ASN   B OD1    1 
ATOM   2263 N  ND2    . ASN   A  1 143 ? 74.325  -24.524 16.147  1.00 45.15  ?  6941 ASN   B ND2    1 
ATOM   2264 H  H      . ASN   A  1 143 ? 72.621  -22.541 20.281  1.00 61.67  ?  6941 ASN   B H      1 
ATOM   2265 H  HA     . ASN   A  1 143 ? 73.883  -21.196 18.275  1.00 63.98  ?  6941 ASN   B HA     1 
ATOM   2266 H  HB2    . ASN   A  1 143 ? 74.665  -23.394 18.636  1.00 60.48  ?  6941 ASN   B HB2    1 
ATOM   2267 H  HB3    . ASN   A  1 143 ? 73.202  -23.938 18.338  1.00 60.48  ?  6941 ASN   B HB3    1 
ATOM   2268 H  HD21   . ASN   A  1 143 ? 74.511  -24.610 15.312  1.00 54.70  ?  6941 ASN   B HD21   1 
ATOM   2269 H  HD22   . ASN   A  1 143 ? 74.238  -25.222 16.642  1.00 54.70  ?  6941 ASN   B HD22   1 
ATOM   2270 N  N      . ASP   A  1 144 ? 71.647  -20.371 17.607  1.00 52.71  ?  6942 ASP   B N      1 
ATOM   2271 C  CA     . ASP   A  1 144 ? 70.394  -19.913 17.035  1.00 53.83  ?  6942 ASP   B CA     1 
ATOM   2272 C  C      . ASP   A  1 144 ? 70.586  -19.665 15.540  1.00 45.11  ?  6942 ASP   B C      1 
ATOM   2273 O  O      . ASP   A  1 144 ? 71.705  -19.460 15.058  1.00 45.35  ?  6942 ASP   B O      1 
ATOM   2274 C  CB     . ASP   A  1 144 ? 69.937  -18.634 17.750  1.00 64.00  ?  6942 ASP   B CB     1 
ATOM   2275 C  CG     . ASP   A  1 144 ? 69.266  -18.905 19.082  1.00 85.79  ?  6942 ASP   B CG     1 
ATOM   2276 O  OD1    . ASP   A  1 144 ? 68.500  -19.877 19.189  1.00 78.38  ?  6942 ASP   B OD1    1 
ATOM   2277 O  OD2    . ASP   A  1 144 ? 69.537  -18.152 20.034  1.00 88.69  ?  6942 ASP   B OD2    1 
ATOM   2278 H  H      . ASP   A  1 144 ? 72.193  -19.726 17.769  1.00 63.77  ?  6942 ASP   B H      1 
ATOM   2279 H  HA     . ASP   A  1 144 ? 69.696  -20.578 17.143  1.00 65.12  ?  6942 ASP   B HA     1 
ATOM   2280 H  HB2    . ASP   A  1 144 ? 70.710  -18.072 17.914  1.00 77.32  ?  6942 ASP   B HB2    1 
ATOM   2281 H  HB3    . ASP   A  1 144 ? 69.301  -18.168 17.186  1.00 77.32  ?  6942 ASP   B HB3    1 
ATOM   2282 N  N      . SER   A  1 145 ? 69.483  -19.732 14.802  1.00 47.29  ?  6943 SER   B N      1 
ATOM   2283 C  CA     . SER   A  1 145 ? 69.501  -19.368 13.393  1.00 41.12  ?  6943 SER   B CA     1 
ATOM   2284 C  C      . SER   A  1 145 ? 70.157  -18.002 13.227  1.00 41.26  ?  6943 SER   B C      1 
ATOM   2285 O  O      . SER   A  1 145 ? 69.847  -17.057 13.952  1.00 43.59  ?  6943 SER   B O      1 
ATOM   2286 C  CB     . SER   A  1 145 ? 68.086  -19.352 12.815  1.00 41.54  ?  6943 SER   B CB     1 
ATOM   2287 O  OG     . SER   A  1 145 ? 68.120  -18.985 11.444  1.00 46.36  ?  6943 SER   B OG     1 
ATOM   2288 H  H      . SER   A  1 145 ? 68.714  -19.984 15.093  1.00 57.28  ?  6943 SER   B H      1 
ATOM   2289 H  HA     . SER   A  1 145 ? 70.006  -20.029 12.895  1.00 49.86  ?  6943 SER   B HA     1 
ATOM   2290 H  HB2    . SER   A  1 145 ? 67.698  -20.237 12.899  1.00 50.37  ?  6943 SER   B HB2    1 
ATOM   2291 H  HB3    . SER   A  1 145 ? 67.550  -18.708 13.304  1.00 50.37  ?  6943 SER   B HB3    1 
ATOM   2292 H  HG     . SER   A  1 145 ? 67.341  -18.848 11.164  1.00 56.16  ?  6943 SER   B HG     1 
ATOM   2293 N  N      . LYS   A  1 146 ? 71.074  -17.906 12.274  1.00 47.86  ?  6944 LYS   B N      1 
ATOM   2294 C  CA     . LYS   A  1 146 ? 71.827  -16.686 12.030  1.00 42.27  ?  6944 LYS   B CA     1 
ATOM   2295 C  C      . LYS   A  1 146 ? 71.180  -15.898 10.902  1.00 41.37  ?  6944 LYS   B C      1 
ATOM   2296 O  O      . LYS   A  1 146 ? 70.575  -16.470 9.995   1.00 46.36  ?  6944 LYS   B O      1 
ATOM   2297 C  CB     . LYS   A  1 146 ? 73.275  -17.012 11.677  1.00 43.18  ?  6944 LYS   B CB     1 
ATOM   2298 C  CG     . LYS   A  1 146 ? 73.931  -17.959 12.663  1.00 45.47  ?  6944 LYS   B CG     1 
ATOM   2299 C  CD     . LYS   A  1 146 ? 74.065  -17.252 14.011  1.00 46.09  ?  6944 LYS   B CD     1 
ATOM   2300 C  CE     . LYS   A  1 146 ? 74.911  -18.062 14.982  1.00 43.03  ?  6944 LYS   B CE     1 
ATOM   2301 N  NZ     . LYS   A  1 146 ? 74.370  -19.422 15.243  1.00 49.71  ?  6944 LYS   B NZ     1 
ATOM   2302 H  H      . LYS   A  1 146 ? 71.282  -18.550 11.743  1.00 57.95  ?  6944 LYS   B H      1 
ATOM   2303 H  HA     . LYS   A  1 146 ? 71.830  -16.134 12.827  1.00 51.24  ?  6944 LYS   B HA     1 
ATOM   2304 H  HB2    . LYS   A  1 146 ? 73.299  -17.429 10.801  1.00 52.34  ?  6944 LYS   B HB2    1 
ATOM   2305 H  HB3    . LYS   A  1 146 ? 73.789  -16.189 11.666  1.00 52.34  ?  6944 LYS   B HB3    1 
ATOM   2306 H  HG2    . LYS   A  1 146 ? 73.383  -18.752 12.775  1.00 55.08  ?  6944 LYS   B HG2    1 
ATOM   2307 H  HG3    . LYS   A  1 146 ? 74.814  -18.208 12.347  1.00 55.08  ?  6944 LYS   B HG3    1 
ATOM   2308 H  HD2    . LYS   A  1 146 ? 74.490  -16.390 13.880  1.00 55.83  ?  6944 LYS   B HD2    1 
ATOM   2309 H  HD3    . LYS   A  1 146 ? 73.185  -17.132 14.400  1.00 55.83  ?  6944 LYS   B HD3    1 
ATOM   2310 H  HE2    . LYS   A  1 146 ? 75.803  -18.163 14.613  1.00 52.15  ?  6944 LYS   B HE2    1 
ATOM   2311 H  HE3    . LYS   A  1 146 ? 74.954  -17.591 15.829  1.00 52.15  ?  6944 LYS   B HE3    1 
ATOM   2312 H  HZ1    . LYS   A  1 146 ? 74.316  -19.880 14.482  1.00 60.18  ?  6944 LYS   B HZ1    1 
ATOM   2313 H  HZ2    . LYS   A  1 146 ? 74.903  -19.859 15.806  1.00 60.18  ?  6944 LYS   B HZ2    1 
ATOM   2314 H  HZ3    . LYS   A  1 146 ? 73.557  -19.363 15.602  1.00 60.18  ?  6944 LYS   B HZ3    1 
ATOM   2315 N  N      . GLU   A  1 147 ? 71.320  -14.577 10.955  1.00 46.87  ?  6945 GLU   B N      1 
ATOM   2316 C  CA     . GLU   A  1 147 ? 70.752  -13.738 9.908   1.00 47.25  ?  6945 GLU   B CA     1 
ATOM   2317 C  C      . GLU   A  1 147 ? 71.899  -13.227 9.045   1.00 40.56  ?  6945 GLU   B C      1 
ATOM   2318 O  O      . GLU   A  1 147 ? 72.527  -14.007 8.314   1.00 48.26  ?  6945 GLU   B O      1 
ATOM   2319 C  CB     . GLU   A  1 147 ? 69.892  -12.636 10.529  1.00 43.37  ?  6945 GLU   B CB     1 
ATOM   2320 C  CG     . GLU   A  1 147 ? 68.536  -13.224 10.931  1.00 51.98  ?  6945 GLU   B CG     1 
ATOM   2321 C  CD     . GLU   A  1 147 ? 67.768  -12.382 11.882  1.00 68.31  ?  6945 GLU   B CD     1 
ATOM   2322 O  OE1    . GLU   A  1 147 ? 68.394  -11.643 12.656  1.00 76.83  ?  6945 GLU   B OE1    1 
ATOM   2323 O  OE2    . GLU   A  1 147 ? 66.529  -12.485 11.870  1.00 89.39  ?  6945 GLU   B OE2    1 
ATOM   2324 H  H      . GLU   A  1 147 ? 71.732  -14.150 11.577  1.00 56.76  ?  6945 GLU   B H      1 
ATOM   2325 H  HA     . GLU   A  1 147 ? 70.147  -14.224 9.326   1.00 57.22  ?  6945 GLU   B HA     1 
ATOM   2326 H  HB2    . GLU   A  1 147 ? 70.330  -12.282 11.319  1.00 52.56  ?  6945 GLU   B HB2    1 
ATOM   2327 H  HB3    . GLU   A  1 147 ? 69.749  -11.926 9.883   1.00 52.56  ?  6945 GLU   B HB3    1 
ATOM   2328 H  HG2    . GLU   A  1 147 ? 67.996  -13.335 10.133  1.00 62.89  ?  6945 GLU   B HG2    1 
ATOM   2329 H  HG3    . GLU   A  1 147 ? 68.684  -14.085 11.354  1.00 62.89  ?  6945 GLU   B HG3    1 
ATOM   2330 N  N      . GLY   A  1 148 ? 72.193  -11.939 9.120   1.00 43.37  ?  6946 GLY   B N      1 
ATOM   2331 C  CA     . GLY   A  1 148 ? 73.359  -11.421 8.416   1.00 40.57  ?  6946 GLY   B CA     1 
ATOM   2332 C  C      . GLY   A  1 148 ? 73.286  -11.704 6.928   1.00 36.52  ?  6946 GLY   B C      1 
ATOM   2333 O  O      . GLY   A  1 148 ? 72.268  -11.440 6.275   1.00 43.00  ?  6946 GLY   B O      1 
ATOM   2334 H  H      . GLY   A  1 148 ? 71.745  -11.353 9.562   1.00 52.57  ?  6946 GLY   B H      1 
ATOM   2335 H  HA2    . GLY   A  1 148 ? 73.416  -10.461 8.544   1.00 49.21  ?  6946 GLY   B HA2    1 
ATOM   2336 H  HA3    . GLY   A  1 148 ? 74.162  -11.835 8.769   1.00 49.21  ?  6946 GLY   B HA3    1 
ATOM   2337 N  N      . PHE   A  1 149 ? 74.379  -12.246 6.365   1.00 41.88  ?  6947 PHE   B N      1 
ATOM   2338 C  CA     . PHE   A  1 149 ? 74.433  -12.522 4.925   1.00 40.43  ?  6947 PHE   B CA     1 
ATOM   2339 C  C      . PHE   A  1 149 ? 73.418  -13.580 4.513   1.00 41.34  ?  6947 PHE   B C      1 
ATOM   2340 O  O      . PHE   A  1 149 ? 73.050  -13.649 3.337   1.00 42.33  ?  6947 PHE   B O      1 
ATOM   2341 C  CB     . PHE   A  1 149 ? 75.878  -12.896 4.495   1.00 41.44  ?  6947 PHE   B CB     1 
ATOM   2342 C  CG     . PHE   A  1 149 ? 76.385  -14.232 5.006   1.00 44.09  ?  6947 PHE   B CG     1 
ATOM   2343 C  CD1    . PHE   A  1 149 ? 75.824  -15.434 4.585   1.00 39.97  ?  6947 PHE   B CD1    1 
ATOM   2344 C  CD2    . PHE   A  1 149 ? 77.475  -14.273 5.870   1.00 38.05  ?  6947 PHE   B CD2    1 
ATOM   2345 C  CE1    . PHE   A  1 149 ? 76.307  -16.646 5.053   1.00 36.33  ?  6947 PHE   B CE1    1 
ATOM   2346 C  CE2    . PHE   A  1 149 ? 77.971  -15.490 6.344   1.00 39.53  ?  6947 PHE   B CE2    1 
ATOM   2347 C  CZ     . PHE   A  1 149 ? 77.385  -16.677 5.932   1.00 35.78  ?  6947 PHE   B CZ     1 
ATOM   2348 H  H      . PHE   A  1 149 ? 75.095  -12.459 6.792   1.00 50.78  ?  6947 PHE   B H      1 
ATOM   2349 H  HA     . PHE   A  1 149 ? 74.211  -11.716 4.433   1.00 49.04  ?  6947 PHE   B HA     1 
ATOM   2350 H  HB2    . PHE   A  1 149 ? 75.911  -12.926 3.526   1.00 50.25  ?  6947 PHE   B HB2    1 
ATOM   2351 H  HB3    . PHE   A  1 149 ? 76.482  -12.212 4.826   1.00 50.25  ?  6947 PHE   B HB3    1 
ATOM   2352 H  HD1    . PHE   A  1 149 ? 75.116  -15.424 3.982   1.00 48.49  ?  6947 PHE   B HD1    1 
ATOM   2353 H  HD2    . PHE   A  1 149 ? 77.879  -13.478 6.135   1.00 46.18  ?  6947 PHE   B HD2    1 
ATOM   2354 H  HE1    . PHE   A  1 149 ? 75.909  -17.441 4.778   1.00 44.12  ?  6947 PHE   B HE1    1 
ATOM   2355 H  HE2    . PHE   A  1 149 ? 78.690  -15.503 6.933   1.00 47.96  ?  6947 PHE   B HE2    1 
ATOM   2356 H  HZ     . PHE   A  1 149 ? 77.710  -17.491 6.243   1.00 43.46  ?  6947 PHE   B HZ     1 
ATOM   2357 N  N      . PHE   A  1 150 ? 72.918  -14.374 5.464   1.00 44.54  ?  6948 PHE   B N      1 
ATOM   2358 C  CA     . PHE   A  1 150 ? 71.924  -15.383 5.119   1.00 39.32  ?  6948 PHE   B CA     1 
ATOM   2359 C  C      . PHE   A  1 150 ? 70.594  -14.751 4.738   1.00 42.98  ?  6948 PHE   B C      1 
ATOM   2360 O  O      . PHE   A  1 150 ? 69.868  -15.288 3.891   1.00 42.66  ?  6948 PHE   B O      1 
ATOM   2361 C  CB     . PHE   A  1 150 ? 71.697  -16.356 6.279   1.00 43.45  ?  6948 PHE   B CB     1 
ATOM   2362 C  CG     . PHE   A  1 150 ? 72.769  -17.386 6.422   1.00 38.93  ?  6948 PHE   B CG     1 
ATOM   2363 C  CD1    . PHE   A  1 150 ? 72.928  -18.378 5.469   1.00 37.18  ?  6948 PHE   B CD1    1 
ATOM   2364 C  CD2    . PHE   A  1 150 ? 73.609  -17.387 7.520   1.00 40.47  ?  6948 PHE   B CD2    1 
ATOM   2365 C  CE1    . PHE   A  1 150 ? 73.930  -19.342 5.610   1.00 38.15  ?  6948 PHE   B CE1    1 
ATOM   2366 C  CE2    . PHE   A  1 150 ? 74.601  -18.336 7.656   1.00 38.63  ?  6948 PHE   B CE2    1 
ATOM   2367 C  CZ     . PHE   A  1 150 ? 74.760  -19.313 6.709   1.00 40.65  ?  6948 PHE   B CZ     1 
ATOM   2368 H  H      . PHE   A  1 150 ? 73.135  -14.348 6.296   1.00 53.98  ?  6948 PHE   B H      1 
ATOM   2369 H  HA     . PHE   A  1 150 ? 72.268  -15.886 4.365   1.00 47.70  ?  6948 PHE   B HA     1 
ATOM   2370 H  HB2    . PHE   A  1 150 ? 71.661  -15.851 7.107   1.00 52.67  ?  6948 PHE   B HB2    1 
ATOM   2371 H  HB3    . PHE   A  1 150 ? 70.858  -16.821 6.137   1.00 52.67  ?  6948 PHE   B HB3    1 
ATOM   2372 H  HD1    . PHE   A  1 150 ? 72.365  -18.402 4.729   1.00 45.14  ?  6948 PHE   B HD1    1 
ATOM   2373 H  HD2    . PHE   A  1 150 ? 73.504  -16.737 8.177   1.00 49.08  ?  6948 PHE   B HD2    1 
ATOM   2374 H  HE1    . PHE   A  1 150 ? 74.036  -20.002 4.963   1.00 46.30  ?  6948 PHE   B HE1    1 
ATOM   2375 H  HE2    . PHE   A  1 150 ? 75.166  -18.312 8.394   1.00 46.87  ?  6948 PHE   B HE2    1 
ATOM   2376 H  HZ     . PHE   A  1 150 ? 75.426  -19.954 6.808   1.00 49.30  ?  6948 PHE   B HZ     1 
ATOM   2377 N  N      . THR   A  1 151 ? 70.232  -13.642 5.383   1.00 44.34  ?  6949 THR   B N      1 
ATOM   2378 C  CA     . THR   A  1 151 ? 69.013  -12.951 5.001   1.00 44.52  ?  6949 THR   B CA     1 
ATOM   2379 C  C      . THR   A  1 151 ? 69.124  -12.442 3.573   1.00 43.23  ?  6949 THR   B C      1 
ATOM   2380 O  O      . THR   A  1 151 ? 68.193  -12.601 2.770   1.00 47.97  ?  6949 THR   B O      1 
ATOM   2381 C  CB     . THR   A  1 151 ? 68.738  -11.812 5.970   1.00 43.63  ?  6949 THR   B CB     1 
ATOM   2382 O  OG1    . THR   A  1 151 ? 68.581  -12.349 7.289   1.00 51.00  ?  6949 THR   B OG1    1 
ATOM   2383 C  CG2    . THR   A  1 151 ? 67.460  -11.076 5.574   1.00 49.24  ?  6949 THR   B CG2    1 
ATOM   2384 H  H      . THR   A  1 151 ? 70.668  -13.280 6.031   1.00 53.73  ?  6949 THR   B H      1 
ATOM   2385 H  HA     . THR   A  1 151 ? 68.260  -13.560 5.050   1.00 53.95  ?  6949 THR   B HA     1 
ATOM   2386 H  HB     . THR   A  1 151 ? 69.475  -11.181 5.956   1.00 52.88  ?  6949 THR   B HB     1 
ATOM   2387 H  HG1    . THR   A  1 151 ? 68.478  -11.725 7.843   1.00 61.72  ?  6949 THR   B HG1    1 
ATOM   2388 H  HG21   . THR   A  1 151 ? 67.146  -10.534 6.314   1.00 59.61  ?  6949 THR   B HG21   1 
ATOM   2389 H  HG22   . THR   A  1 151 ? 67.632  -10.500 4.813   1.00 59.61  ?  6949 THR   B HG22   1 
ATOM   2390 H  HG23   . THR   A  1 151 ? 66.770  -11.714 5.336   1.00 59.61  ?  6949 THR   B HG23   1 
ATOM   2391 N  N      . TYR   A  1 152 ? 70.268  -11.837 3.234   1.00 45.73  ?  6950 TYR   B N      1 
ATOM   2392 C  CA     . TYR   A  1 152 ? 70.524  -11.436 1.855   1.00 44.65  ?  6950 TYR   B CA     1 
ATOM   2393 C  C      . TYR   A  1 152 ? 70.353  -12.609 0.903   1.00 39.35  ?  6950 TYR   B C      1 
ATOM   2394 O  O      . TYR   A  1 152 ? 69.712  -12.487 -0.147  1.00 43.55  ?  6950 TYR   B O      1 
ATOM   2395 C  CB     . TYR   A  1 152 ? 71.935  -10.853 1.731   1.00 44.57  ?  6950 TYR   B CB     1 
ATOM   2396 C  CG     . TYR   A  1 152 ? 72.265  -10.486 0.303   1.00 46.24  ?  6950 TYR   B CG     1 
ATOM   2397 C  CD1    . TYR   A  1 152 ? 71.732  -9.334  -0.264  1.00 41.11  ?  6950 TYR   B CD1    1 
ATOM   2398 C  CD2    . TYR   A  1 152 ? 73.078  -11.306 -0.484  1.00 47.11  ?  6950 TYR   B CD2    1 
ATOM   2399 C  CE1    . TYR   A  1 152 ? 71.998  -9.000  -1.571  1.00 45.60  ?  6950 TYR   B CE1    1 
ATOM   2400 C  CE2    . TYR   A  1 152 ? 73.366  -10.976 -1.792  1.00 41.04  ?  6950 TYR   B CE2    1 
ATOM   2401 C  CZ     . TYR   A  1 152 ? 72.816  -9.820  -2.334  1.00 46.72  ?  6950 TYR   B CZ     1 
ATOM   2402 O  OH     . TYR   A  1 152 ? 73.078  -9.468  -3.639  1.00 46.98  ?  6950 TYR   B OH     1 
ATOM   2403 H  H      . TYR   A  1 152 ? 70.905  -11.651 3.782   1.00 55.39  ?  6950 TYR   B H      1 
ATOM   2404 H  HA     . TYR   A  1 152 ? 69.887  -10.747 1.609   1.00 54.10  ?  6950 TYR   B HA     1 
ATOM   2405 H  HB2    . TYR   A  1 152 ? 71.999  -10.052 2.274   1.00 54.00  ?  6950 TYR   B HB2    1 
ATOM   2406 H  HB3    . TYR   A  1 152 ? 72.581  -11.511 2.033   1.00 54.00  ?  6950 TYR   B HB3    1 
ATOM   2407 H  HD1    . TYR   A  1 152 ? 71.186  -8.782  0.247   1.00 49.86  ?  6950 TYR   B HD1    1 
ATOM   2408 H  HD2    . TYR   A  1 152 ? 73.431  -12.086 -0.120  1.00 57.05  ?  6950 TYR   B HD2    1 
ATOM   2409 H  HE1    . TYR   A  1 152 ? 71.633  -8.229  -1.940  1.00 55.24  ?  6950 TYR   B HE1    1 
ATOM   2410 H  HE2    . TYR   A  1 152 ? 73.921  -11.519 -2.305  1.00 49.77  ?  6950 TYR   B HE2    1 
ATOM   2411 H  HH     . TYR   A  1 152 ? 72.700  -8.740  -3.821  1.00 56.90  ?  6950 TYR   B HH     1 
ATOM   2412 N  N      . ILE   A  1 153 ? 70.925  -13.758 1.253   1.00 46.75  ?  6951 ILE   B N      1 
ATOM   2413 C  CA     . ILE   A  1 153 ? 70.985  -14.869 0.306   1.00 39.97  ?  6951 ILE   B CA     1 
ATOM   2414 C  C      . ILE   A  1 153 ? 69.599  -15.453 0.059   1.00 41.95  ?  6951 ILE   B C      1 
ATOM   2415 O  O      . ILE   A  1 153 ? 69.280  -15.864 -1.062  1.00 41.59  ?  6951 ILE   B O      1 
ATOM   2416 C  CB     . ILE   A  1 153 ? 71.970  -15.932 0.821   1.00 39.24  ?  6951 ILE   B CB     1 
ATOM   2417 C  CG1    . ILE   A  1 153 ? 73.406  -15.607 0.402   1.00 50.90  ?  6951 ILE   B CG1    1 
ATOM   2418 C  CG2    . ILE   A  1 153 ? 71.594  -17.313 0.276   1.00 40.89  ?  6951 ILE   B CG2    1 
ATOM   2419 C  CD1    . ILE   A  1 153 ? 73.619  -15.588 -1.114  1.00 53.22  ?  6951 ILE   B CD1    1 
ATOM   2420 H  H      . ILE   A  1 153 ? 71.281  -13.919 2.019   1.00 56.62  ?  6951 ILE   B H      1 
ATOM   2421 H  HA     . ILE   A  1 153 ? 71.310  -14.534 -0.544  1.00 48.48  ?  6951 ILE   B HA     1 
ATOM   2422 H  HB     . ILE   A  1 153 ? 71.917  -15.931 1.789   1.00 47.60  ?  6951 ILE   B HB     1 
ATOM   2423 H  HG12   . ILE   A  1 153 ? 73.639  -14.730 0.745   1.00 61.60  ?  6951 ILE   B HG12   1 
ATOM   2424 H  HG13   . ILE   A  1 153 ? 73.999  -16.278 0.775   1.00 61.60  ?  6951 ILE   B HG13   1 
ATOM   2425 H  HG21   . ILE   A  1 153 ? 72.358  -17.905 0.362   1.00 49.60  ?  6951 ILE   B HG21   1 
ATOM   2426 H  HG22   . ILE   A  1 153 ? 70.847  -17.660 0.787   1.00 49.60  ?  6951 ILE   B HG22   1 
ATOM   2427 H  HG23   . ILE   A  1 153 ? 71.345  -17.227 -0.657  1.00 49.60  ?  6951 ILE   B HG23   1 
ATOM   2428 H  HD11   . ILE   A  1 153 ? 74.570  -15.618 -1.300  1.00 64.39  ?  6951 ILE   B HD11   1 
ATOM   2429 H  HD12   . ILE   A  1 153 ? 73.181  -16.360 -1.504  1.00 64.39  ?  6951 ILE   B HD12   1 
ATOM   2430 H  HD13   . ILE   A  1 153 ? 73.237  -14.773 -1.476  1.00 64.39  ?  6951 ILE   B HD13   1 
ATOM   2431 N  N      . CYS   A  1 154 ? 68.768  -15.548 1.100   1.00 41.45  ?  6952 CYS   B N      1 
ATOM   2432 C  CA     . CYS   A  1 154 ? 67.403  -16.016 0.877   1.00 44.55  ?  6952 CYS   B CA     1 
ATOM   2433 C  C      . CYS   A  1 154 ? 66.632  -15.054 -0.017  1.00 44.38  ?  6952 CYS   B C      1 
ATOM   2434 O  O      . CYS   A  1 154 ? 65.845  -15.497 -0.865  1.00 45.77  ?  6952 CYS   B O      1 
ATOM   2435 C  CB     . CYS   A  1 154 ? 66.659  -16.232 2.198   1.00 46.59  ?  6952 CYS   B CB     1 
ATOM   2436 S  SG     . CYS   A  1 154 ? 67.365  -17.445 3.313   1.00 47.23  ?  6952 CYS   B SG     1 
ATOM   2437 H  H      . CYS   A  1 154 ? 68.964  -15.354 1.915   1.00 50.26  ?  6952 CYS   B H      1 
ATOM   2438 H  HA     . CYS   A  1 154 ? 67.454  -16.878 0.436   1.00 53.99  ?  6952 CYS   B HA     1 
ATOM   2439 H  HB2    . CYS   A  1 154 ? 66.636  -15.387 2.673   1.00 56.43  ?  6952 CYS   B HB2    1 
ATOM   2440 H  HB3    . CYS   A  1 154 ? 65.757  -16.523 1.993   1.00 56.43  ?  6952 CYS   B HB3    1 
ATOM   2441 H  HG     . CYS   A  1 154 ? 68.511  -17.161 3.526   1.00 57.20  ?  6952 CYS   B HG     1 
ATOM   2442 N  N      . GLY   A  1 155 ? 66.831  -13.745 0.166   1.00 42.64  ?  6953 GLY   B N      1 
ATOM   2443 C  CA     . GLY   A  1 155 ? 66.210  -12.781 -0.722  1.00 41.95  ?  6953 GLY   B CA     1 
ATOM   2444 C  C      . GLY   A  1 155 ? 66.725  -12.885 -2.143  1.00 44.44  ?  6953 GLY   B C      1 
ATOM   2445 O  O      . GLY   A  1 155 ? 65.946  -12.867 -3.102  1.00 45.27  ?  6953 GLY   B O      1 
ATOM   2446 H  H      . GLY   A  1 155 ? 67.314  -13.401 0.788   1.00 51.69  ?  6953 GLY   B H      1 
ATOM   2447 H  HA2    . GLY   A  1 155 ? 65.251  -12.927 -0.733  1.00 50.86  ?  6953 GLY   B HA2    1 
ATOM   2448 H  HA3    . GLY   A  1 155 ? 66.389  -11.885 -0.397  1.00 50.86  ?  6953 GLY   B HA3    1 
ATOM   2449 N  N      . PHE   A  1 156 ? 68.039  -13.016 -2.297  1.00 45.02  ?  6954 PHE   B N      1 
ATOM   2450 C  CA     . PHE   A  1 156 ? 68.623  -13.083 -3.626  1.00 42.71  ?  6954 PHE   B CA     1 
ATOM   2451 C  C      . PHE   A  1 156 ? 68.149  -14.315 -4.379  1.00 43.36  ?  6954 PHE   B C      1 
ATOM   2452 O  O      . PHE   A  1 156 ? 67.974  -14.256 -5.599  1.00 44.93  ?  6954 PHE   B O      1 
ATOM   2453 C  CB     . PHE   A  1 156 ? 70.143  -13.065 -3.513  1.00 46.47  ?  6954 PHE   B CB     1 
ATOM   2454 C  CG     . PHE   A  1 156 ? 70.844  -12.831 -4.809  1.00 43.02  ?  6954 PHE   B CG     1 
ATOM   2455 C  CD1    . PHE   A  1 156 ? 71.127  -13.882 -5.659  1.00 40.53  ?  6954 PHE   B CD1    1 
ATOM   2456 C  CD2    . PHE   A  1 156 ? 71.222  -11.551 -5.177  1.00 43.80  ?  6954 PHE   B CD2    1 
ATOM   2457 C  CE1    . PHE   A  1 156 ? 71.780  -13.656 -6.858  1.00 45.97  ?  6954 PHE   B CE1    1 
ATOM   2458 C  CE2    . PHE   A  1 156 ? 71.878  -11.321 -6.379  1.00 50.16  ?  6954 PHE   B CE2    1 
ATOM   2459 C  CZ     . PHE   A  1 156 ? 72.153  -12.375 -7.219  1.00 46.40  ?  6954 PHE   B CZ     1 
ATOM   2460 H  H      . PHE   A  1 156 ? 68.608  -13.067 -1.653  1.00 54.55  ?  6954 PHE   B H      1 
ATOM   2461 H  HA     . PHE   A  1 156 ? 68.351  -12.305 -4.138  1.00 51.77  ?  6954 PHE   B HA     1 
ATOM   2462 H  HB2    . PHE   A  1 156 ? 70.402  -12.356 -2.905  1.00 56.28  ?  6954 PHE   B HB2    1 
ATOM   2463 H  HB3    . PHE   A  1 156 ? 70.439  -13.922 -3.168  1.00 56.28  ?  6954 PHE   B HB3    1 
ATOM   2464 H  HD1    . PHE   A  1 156 ? 70.878  -14.747 -5.424  1.00 49.16  ?  6954 PHE   B HD1    1 
ATOM   2465 H  HD2    . PHE   A  1 156 ? 71.034  -10.837 -4.613  1.00 53.08  ?  6954 PHE   B HD2    1 
ATOM   2466 H  HE1    . PHE   A  1 156 ? 71.968  -14.369 -7.424  1.00 55.68  ?  6954 PHE   B HE1    1 
ATOM   2467 H  HE2    . PHE   A  1 156 ? 72.130  -10.458 -6.615  1.00 60.71  ?  6954 PHE   B HE2    1 
ATOM   2468 H  HZ     . PHE   A  1 156 ? 72.589  -12.225 -8.027  1.00 56.20  ?  6954 PHE   B HZ     1 
ATOM   2469 N  N      . ILE   A  1 157 ? 67.903  -15.420 -3.673  1.00 41.38  ?  6955 ILE   B N      1 
ATOM   2470 C  CA     . ILE   A  1 157 ? 67.421  -16.629 -4.330  1.00 45.36  ?  6955 ILE   B CA     1 
ATOM   2471 C  C      . ILE   A  1 157 ? 66.006  -16.419 -4.845  1.00 44.87  ?  6955 ILE   B C      1 
ATOM   2472 O  O      . ILE   A  1 157 ? 65.703  -16.704 -6.008  1.00 48.90  ?  6955 ILE   B O      1 
ATOM   2473 C  CB     . ILE   A  1 157 ? 67.503  -17.830 -3.369  1.00 47.13  ?  6955 ILE   B CB     1 
ATOM   2474 C  CG1    . ILE   A  1 157 ? 68.969  -18.202 -3.191  1.00 46.40  ?  6955 ILE   B CG1    1 
ATOM   2475 C  CG2    . ILE   A  1 157 ? 66.699  -18.986 -3.915  1.00 50.25  ?  6955 ILE   B CG2    1 
ATOM   2476 C  CD1    . ILE   A  1 157 ? 69.233  -19.239 -2.110  1.00 39.59  ?  6955 ILE   B CD1    1 
ATOM   2477 H  H      . ILE   A  1 157 ? 68.007  -15.493 -2.822  1.00 50.17  ?  6955 ILE   B H      1 
ATOM   2478 H  HA     . ILE   A  1 157 ? 67.993  -16.817 -5.091  1.00 54.95  ?  6955 ILE   B HA     1 
ATOM   2479 H  HB     . ILE   A  1 157 ? 67.128  -17.599 -2.506  1.00 57.08  ?  6955 ILE   B HB     1 
ATOM   2480 H  HG12   . ILE   A  1 157 ? 69.300  -18.563 -4.029  1.00 56.20  ?  6955 ILE   B HG12   1 
ATOM   2481 H  HG13   . ILE   A  1 157 ? 69.465  -17.402 -2.956  1.00 56.20  ?  6955 ILE   B HG13   1 
ATOM   2482 H  HG21   . ILE   A  1 157 ? 66.936  -19.792 -3.430  1.00 60.83  ?  6955 ILE   B HG21   1 
ATOM   2483 H  HG22   . ILE   A  1 157 ? 65.755  -18.796 -3.799  1.00 60.83  ?  6955 ILE   B HG22   1 
ATOM   2484 H  HG23   . ILE   A  1 157 ? 66.902  -19.095 -4.857  1.00 60.83  ?  6955 ILE   B HG23   1 
ATOM   2485 H  HD11   . ILE   A  1 157 ? 70.190  -19.305 -1.961  1.00 48.03  ?  6955 ILE   B HD11   1 
ATOM   2486 H  HD12   . ILE   A  1 157 ? 68.790  -18.963 -1.292  1.00 48.03  ?  6955 ILE   B HD12   1 
ATOM   2487 H  HD13   . ILE   A  1 157 ? 68.884  -20.096 -2.402  1.00 48.03  ?  6955 ILE   B HD13   1 
ATOM   2488 N  N      . GLN   A  1 158 ? 65.130  -15.886 -3.999  1.00 45.78  ?  6956 GLN   B N      1 
ATOM   2489 C  CA     . GLN   A  1 158 ? 63.740  -15.723 -4.391  1.00 49.15  ?  6956 GLN   B CA     1 
ATOM   2490 C  C      . GLN   A  1 158 ? 63.603  -14.712 -5.517  1.00 43.95  ?  6956 GLN   B C      1 
ATOM   2491 O  O      . GLN   A  1 158 ? 62.800  -14.902 -6.439  1.00 54.28  ?  6956 GLN   B O      1 
ATOM   2492 C  CB     . GLN   A  1 158 ? 62.930  -15.311 -3.170  1.00 44.11  ?  6956 GLN   B CB     1 
ATOM   2493 C  CG     . GLN   A  1 158 ? 62.561  -16.552 -2.364  1.00 51.43  ?  6956 GLN   B CG     1 
ATOM   2494 C  CD     . GLN   A  1 158 ? 62.021  -16.240 -0.988  1.00 49.94  ?  6956 GLN   B CD     1 
ATOM   2495 O  OE1    . GLN   A  1 158 ? 62.685  -15.598 -0.184  1.00 54.34  ?  6956 GLN   B OE1    1 
ATOM   2496 N  NE2    . GLN   A  1 158 ? 60.833  -16.728 -0.696  1.00 62.14  ?  6956 GLN   B NE2    1 
ATOM   2497 H  H      . GLN   A  1 158 ? 65.314  -15.615 -3.204  1.00 55.46  ?  6956 GLN   B H      1 
ATOM   2498 H  HA     . GLN   A  1 158 ? 63.387  -16.565 -4.719  1.00 59.50  ?  6956 GLN   B HA     1 
ATOM   2499 H  HB2    . GLN   A  1 158 ? 63.457  -14.718 -2.611  1.00 53.45  ?  6956 GLN   B HB2    1 
ATOM   2500 H  HB3    . GLN   A  1 158 ? 62.116  -14.865 -3.451  1.00 53.45  ?  6956 GLN   B HB3    1 
ATOM   2501 H  HG2    . GLN   A  1 158 ? 61.878  -17.045 -2.845  1.00 62.24  ?  6956 GLN   B HG2    1 
ATOM   2502 H  HG3    . GLN   A  1 158 ? 63.353  -17.101 -2.254  1.00 62.24  ?  6956 GLN   B HG3    1 
ATOM   2503 H  HE21   . GLN   A  1 158 ? 60.407  -17.198 -1.277  1.00 75.09  ?  6956 GLN   B HE21   1 
ATOM   2504 H  HE22   . GLN   A  1 158 ? 60.484  -16.578 0.075   1.00 75.09  ?  6956 GLN   B HE22   1 
ATOM   2505 N  N      . GLN   A  1 159 ? 64.415  -13.667 -5.487  1.00 47.09  ?  6957 GLN   B N      1 
ATOM   2506 C  CA     . GLN   A  1 159 ? 64.297  -12.584 -6.445  1.00 50.85  ?  6957 GLN   B CA     1 
ATOM   2507 C  C      . GLN   A  1 159 ? 65.113  -12.784 -7.710  1.00 42.42  ?  6957 GLN   B C      1 
ATOM   2508 O  O      . GLN   A  1 159 ? 64.695  -12.321 -8.773  1.00 44.97  ?  6957 GLN   B O      1 
ATOM   2509 C  CB     . GLN   A  1 159 ? 64.734  -11.266 -5.810  1.00 52.29  ?  6957 GLN   B CB     1 
ATOM   2510 C  CG     . GLN   A  1 159 ? 63.992  -10.857 -4.563  1.00 56.37  ?  6957 GLN   B CG     1 
ATOM   2511 C  CD     . GLN   A  1 159 ? 64.622  -9.670  -3.876  1.00 76.78  ?  6957 GLN   B CD     1 
ATOM   2512 O  OE1    . GLN   A  1 159 ? 64.878  -9.682  -2.679  1.00 75.59  ?  6957 GLN   B OE1    1 
ATOM   2513 N  NE2    . GLN   A  1 159 ? 64.978  -8.681  -4.657  1.00 78.31  ?  6957 GLN   B NE2    1 
ATOM   2514 H  H      . GLN   A  1 159 ? 65.049  -13.561 -4.916  1.00 57.03  ?  6957 GLN   B H      1 
ATOM   2515 H  HA     . GLN   A  1 159 ? 63.362  -12.527 -6.697  1.00 61.54  ?  6957 GLN   B HA     1 
ATOM   2516 H  HB2    . GLN   A  1 159 ? 65.672  -11.338 -5.575  1.00 63.27  ?  6957 GLN   B HB2    1 
ATOM   2517 H  HB3    . GLN   A  1 159 ? 64.609  -10.559 -6.462  1.00 63.27  ?  6957 GLN   B HB3    1 
ATOM   2518 H  HG2    . GLN   A  1 159 ? 63.082  -10.619 -4.799  1.00 68.17  ?  6957 GLN   B HG2    1 
ATOM   2519 H  HG3    . GLN   A  1 159 ? 63.990  -11.599 -3.938  1.00 68.17  ?  6957 GLN   B HG3    1 
ATOM   2520 H  HE21   . GLN   A  1 159 ? 64.848  -8.734  -5.505  1.00 94.50  ?  6957 GLN   B HE21   1 
ATOM   2521 H  HE22   . GLN   A  1 159 ? 65.343  -7.978  -4.321  1.00 94.50  ?  6957 GLN   B HE22   1 
ATOM   2522 N  N      . LYS   A  1 160 ? 66.281  -13.428 -7.636  1.00 49.99  ?  6958 LYS   B N      1 
ATOM   2523 C  CA     . LYS   A  1 160 ? 67.193  -13.398 -8.772  1.00 50.96  ?  6958 LYS   B CA     1 
ATOM   2524 C  C      . LYS   A  1 160 ? 67.683  -14.762 -9.254  1.00 45.55  ?  6958 LYS   B C      1 
ATOM   2525 O  O      . LYS   A  1 160 ? 68.528  -14.799 -10.154 1.00 45.40  ?  6958 LYS   B O      1 
ATOM   2526 C  CB     . LYS   A  1 160 ? 68.405  -12.519 -8.436  1.00 48.54  ?  6958 LYS   B CB     1 
ATOM   2527 C  CG     . LYS   A  1 160 ? 68.046  -11.059 -8.133  1.00 52.18  ?  6958 LYS   B CG     1 
ATOM   2528 C  CD     . LYS   A  1 160 ? 67.540  -10.331 -9.365  1.00 54.83  ?  6958 LYS   B CD     1 
ATOM   2529 C  CE     . LYS   A  1 160 ? 66.991  -8.943  -9.049  1.00 54.94  ?  6958 LYS   B CE     1 
ATOM   2530 N  NZ     . LYS   A  1 160 ? 66.784  -8.123  -10.273 1.00 73.42  ?  6958 LYS   B NZ     1 
ATOM   2531 H  H      . LYS   A  1 160 ? 66.556  -13.876 -6.956  1.00 60.51  ?  6958 LYS   B H      1 
ATOM   2532 H  HA     . LYS   A  1 160 ? 66.715  -13.008 -9.521  1.00 61.67  ?  6958 LYS   B HA     1 
ATOM   2533 H  HB2    . LYS   A  1 160 ? 68.847  -12.883 -7.653  1.00 58.77  ?  6958 LYS   B HB2    1 
ATOM   2534 H  HB3    . LYS   A  1 160 ? 69.012  -12.523 -9.192  1.00 58.77  ?  6958 LYS   B HB3    1 
ATOM   2535 H  HG2    . LYS   A  1 160 ? 67.349  -11.035 -7.459  1.00 63.14  ?  6958 LYS   B HG2    1 
ATOM   2536 H  HG3    . LYS   A  1 160 ? 68.835  -10.596 -7.810  1.00 63.14  ?  6958 LYS   B HG3    1 
ATOM   2537 H  HD2    . LYS   A  1 160 ? 68.272  -10.228 -9.993  1.00 66.32  ?  6958 LYS   B HD2    1 
ATOM   2538 H  HD3    . LYS   A  1 160 ? 66.827  -10.851 -9.768  1.00 66.32  ?  6958 LYS   B HD3    1 
ATOM   2539 H  HE2    . LYS   A  1 160 ? 66.136  -9.034  -8.599  1.00 66.45  ?  6958 LYS   B HE2    1 
ATOM   2540 H  HE3    . LYS   A  1 160 ? 67.619  -8.475  -8.476  1.00 66.45  ?  6958 LYS   B HE3    1 
ATOM   2541 H  HZ1    . LYS   A  1 160 ? 66.466  -7.321  -10.052 1.00 88.63  ?  6958 LYS   B HZ1    1 
ATOM   2542 H  HZ2    . LYS   A  1 160 ? 67.555  -8.020  -10.704 1.00 88.63  ?  6958 LYS   B HZ2    1 
ATOM   2543 H  HZ3    . LYS   A  1 160 ? 66.202  -8.525  -10.813 1.00 88.63  ?  6958 LYS   B HZ3    1 
ATOM   2544 N  N      . LEU   A  1 161 ? 67.185  -15.871 -8.708  1.00 41.78  ?  6959 LEU   B N      1 
ATOM   2545 C  CA     . LEU   A  1 161 ? 67.499  -17.185 -9.240  1.00 44.67  ?  6959 LEU   B CA     1 
ATOM   2546 C  C      . LEU   A  1 161 ? 66.469  -17.538 -10.304 1.00 37.61  ?  6959 LEU   B C      1 
ATOM   2547 O  O      . LEU   A  1 161 ? 65.263  -17.501 -10.042 1.00 44.16  ?  6959 LEU   B O      1 
ATOM   2548 C  CB     . LEU   A  1 161 ? 67.503  -18.243 -8.136  1.00 45.57  ?  6959 LEU   B CB     1 
ATOM   2549 C  CG     . LEU   A  1 161 ? 67.980  -19.629 -8.566  1.00 44.33  ?  6959 LEU   B CG     1 
ATOM   2550 C  CD1    . LEU   A  1 161 ? 69.404  -19.596 -9.080  1.00 46.02  ?  6959 LEU   B CD1    1 
ATOM   2551 C  CD2    . LEU   A  1 161 ? 67.850  -20.577 -7.394  1.00 45.16  ?  6959 LEU   B CD2    1 
ATOM   2552 H  H      . LEU   A  1 161 ? 66.661  -15.883 -8.026  1.00 50.66  ?  6959 LEU   B H      1 
ATOM   2553 H  HA     . LEU   A  1 161 ? 68.383  -17.167 -9.640  1.00 54.13  ?  6959 LEU   B HA     1 
ATOM   2554 H  HB2    . LEU   A  1 161 ? 68.090  -17.941 -7.425  1.00 55.20  ?  6959 LEU   B HB2    1 
ATOM   2555 H  HB3    . LEU   A  1 161 ? 66.598  -18.338 -7.800  1.00 55.20  ?  6959 LEU   B HB3    1 
ATOM   2556 H  HG     . LEU   A  1 161 ? 67.431  -19.946 -9.300  1.00 53.72  ?  6959 LEU   B HG     1 
ATOM   2557 H  HD11   . LEU   A  1 161 ? 69.704  -20.505 -9.236  1.00 55.74  ?  6959 LEU   B HD11   1 
ATOM   2558 H  HD12   . LEU   A  1 161 ? 69.429  -19.092 -9.908  1.00 55.74  ?  6959 LEU   B HD12   1 
ATOM   2559 H  HD13   . LEU   A  1 161 ? 69.969  -19.171 -8.416  1.00 55.74  ?  6959 LEU   B HD13   1 
ATOM   2560 H  HD21   . LEU   A  1 161 ? 68.166  -21.455 -7.661  1.00 54.72  ?  6959 LEU   B HD21   1 
ATOM   2561 H  HD22   . LEU   A  1 161 ? 68.384  -20.244 -6.656  1.00 54.72  ?  6959 LEU   B HD22   1 
ATOM   2562 H  HD23   . LEU   A  1 161 ? 66.917  -20.628 -7.131  1.00 54.72  ?  6959 LEU   B HD23   1 
ATOM   2563 N  N      . ALA   A  1 162 ? 66.948  -17.852 -11.507 1.00 43.22  ?  6960 ALA   B N      1 
ATOM   2564 C  CA     . ALA   A  1 162 ? 66.063  -18.318 -12.561 1.00 44.98  ?  6960 ALA   B CA     1 
ATOM   2565 C  C      . ALA   A  1 162 ? 65.366  -19.596 -12.118 1.00 46.16  ?  6960 ALA   B C      1 
ATOM   2566 O  O      . ALA   A  1 162 ? 65.928  -20.410 -11.378 1.00 45.39  ?  6960 ALA   B O      1 
ATOM   2567 C  CB     . ALA   A  1 162 ? 66.843  -18.578 -13.849 1.00 39.62  ?  6960 ALA   B CB     1 
ATOM   2568 H  H      . ALA   A  1 162 ? 67.776  -17.804 -11.732 1.00 52.38  ?  6960 ALA   B H      1 
ATOM   2569 H  HA     . ALA   A  1 162 ? 65.397  -17.638 -12.750 1.00 54.50  ?  6960 ALA   B HA     1 
ATOM   2570 H  HB1    . ALA   A  1 162 ? 66.231  -18.899 -14.529 1.00 48.06  ?  6960 ALA   B HB1    1 
ATOM   2571 H  HB2    . ALA   A  1 162 ? 67.257  -17.750 -14.140 1.00 48.06  ?  6960 ALA   B HB2    1 
ATOM   2572 H  HB3    . ALA   A  1 162 ? 67.525  -19.246 -13.676 1.00 48.06  ?  6960 ALA   B HB3    1 
ATOM   2573 N  N      . LEU   A  1 163 ? 64.118  -19.757 -12.550 1.00 46.15  ?  6961 LEU   B N      1 
ATOM   2574 C  CA     . LEU   A  1 163 ? 63.483  -21.055 -12.408 1.00 43.51  ?  6961 LEU   B CA     1 
ATOM   2575 C  C      . LEU   A  1 163 ? 64.328  -22.105 -13.112 1.00 40.08  ?  6961 LEU   B C      1 
ATOM   2576 O  O      . LEU   A  1 163 ? 64.852  -21.876 -14.202 1.00 42.36  ?  6961 LEU   B O      1 
ATOM   2577 C  CB     . LEU   A  1 163 ? 62.064  -21.048 -12.975 1.00 49.45  ?  6961 LEU   B CB     1 
ATOM   2578 C  CG     . LEU   A  1 163 ? 61.056  -20.125 -12.305 1.00 44.64  ?  6961 LEU   B CG     1 
ATOM   2579 C  CD1    . LEU   A  1 163 ? 59.665  -20.523 -12.797 1.00 51.20  ?  6961 LEU   B CD1    1 
ATOM   2580 C  CD2    . LEU   A  1 163 ? 61.131  -20.226 -10.809 1.00 46.43  ?  6961 LEU   B CD2    1 
ATOM   2581 H  H      . LEU   A  1 163 ? 63.635  -19.148 -12.917 1.00 55.90  ?  6961 LEU   B H      1 
ATOM   2582 H  HA     . LEU   A  1 163 ? 63.408  -21.278 -11.467 1.00 52.73  ?  6961 LEU   B HA     1 
ATOM   2583 H  HB2    . LEU   A  1 163 ? 62.116  -20.781 -13.907 1.00 59.86  ?  6961 LEU   B HB2    1 
ATOM   2584 H  HB3    . LEU   A  1 163 ? 61.710  -21.949 -12.908 1.00 59.86  ?  6961 LEU   B HB3    1 
ATOM   2585 H  HG     . LEU   A  1 163 ? 61.245  -19.201 -12.531 1.00 54.09  ?  6961 LEU   B HG     1 
ATOM   2586 H  HD11   . LEU   A  1 163 ? 59.010  -19.920 -12.413 1.00 61.96  ?  6961 LEU   B HD11   1 
ATOM   2587 H  HD12   . LEU   A  1 163 ? 59.643  -20.464 -13.765 1.00 61.96  ?  6961 LEU   B HD12   1 
ATOM   2588 H  HD13   . LEU   A  1 163 ? 59.480  -21.433 -12.517 1.00 61.96  ?  6961 LEU   B HD13   1 
ATOM   2589 H  HD21   . LEU   A  1 163 ? 60.347  -19.804 -10.425 1.00 56.24  ?  6961 LEU   B HD21   1 
ATOM   2590 H  HD22   . LEU   A  1 163 ? 61.161  -21.162 -10.557 1.00 56.24  ?  6961 LEU   B HD22   1 
ATOM   2591 H  HD23   . LEU   A  1 163 ? 61.933  -19.775 -10.502 1.00 56.24  ?  6961 LEU   B HD23   1 
ATOM   2592 N  N      . GLY   A  1 164 ? 64.451  -23.274 -12.485 1.00 40.75  ?  6962 GLY   B N      1 
ATOM   2593 C  CA     . GLY   A  1 164 ? 65.336  -24.302 -12.966 1.00 40.95  ?  6962 GLY   B CA     1 
ATOM   2594 C  C      . GLY   A  1 164 ? 66.770  -24.178 -12.498 1.00 40.39  ?  6962 GLY   B C      1 
ATOM   2595 O  O      . GLY   A  1 164 ? 67.551  -25.123 -12.686 1.00 42.47  ?  6962 GLY   B O      1 
ATOM   2596 H  H      . GLY   A  1 164 ? 64.022  -23.487 -11.771 1.00 49.42  ?  6962 GLY   B H      1 
ATOM   2597 H  HA2    . GLY   A  1 164 ? 65.002  -25.163 -12.670 1.00 49.66  ?  6962 GLY   B HA2    1 
ATOM   2598 H  HA3    . GLY   A  1 164 ? 65.339  -24.280 -13.936 1.00 49.66  ?  6962 GLY   B HA3    1 
ATOM   2599 N  N      . GLY   A  1 165 ? 67.143  -23.055 -11.904 1.00 45.52  ?  6963 GLY   B N      1 
ATOM   2600 C  CA     . GLY   A  1 165 ? 68.500  -22.860 -11.455 1.00 41.69  ?  6963 GLY   B CA     1 
ATOM   2601 C  C      . GLY   A  1 165 ? 68.793  -23.594 -10.161 1.00 35.01  ?  6963 GLY   B C      1 
ATOM   2602 O  O      . GLY   A  1 165 ? 67.904  -24.114 -9.498  1.00 42.07  ?  6963 GLY   B O      1 
ATOM   2603 H  H      . GLY   A  1 165 ? 66.622  -22.389 -11.749 1.00 55.15  ?  6963 GLY   B H      1 
ATOM   2604 H  HA2    . GLY   A  1 165 ? 69.112  -23.183 -12.135 1.00 50.55  ?  6963 GLY   B HA2    1 
ATOM   2605 H  HA3    . GLY   A  1 165 ? 68.658  -21.914 -11.313 1.00 50.55  ?  6963 GLY   B HA3    1 
ATOM   2606 N  N      . SER   A  1 166 ? 70.072  -23.604 -9.787  1.00 43.07  ?  6964 SER   B N      1 
ATOM   2607 C  CA     . SER   A  1 166 ? 70.530  -24.380 -8.646  1.00 39.04  ?  6964 SER   B CA     1 
ATOM   2608 C  C      . SER   A  1 166 ? 71.415  -23.516 -7.760  1.00 38.43  ?  6964 SER   B C      1 
ATOM   2609 O  O      . SER   A  1 166 ? 71.949  -22.492 -8.192  1.00 37.94  ?  6964 SER   B O      1 
ATOM   2610 C  CB     . SER   A  1 166 ? 71.278  -25.647 -9.090  1.00 36.24  ?  6964 SER   B CB     1 
ATOM   2611 O  OG     . SER   A  1 166 ? 70.371  -26.563 -9.679  1.00 43.17  ?  6964 SER   B OG     1 
ATOM   2612 H  H      . SER   A  1 166 ? 70.695  -23.164 -10.184 1.00 52.21  ?  6964 SER   B H      1 
ATOM   2613 H  HA     . SER   A  1 166 ? 69.768  -24.658 -8.114  1.00 47.37  ?  6964 SER   B HA     1 
ATOM   2614 H  HB2    . SER   A  1 166 ? 71.956  -25.406 -9.741  1.00 44.01  ?  6964 SER   B HB2    1 
ATOM   2615 H  HB3    . SER   A  1 166 ? 71.693  -26.061 -8.317  1.00 44.01  ?  6964 SER   B HB3    1 
ATOM   2616 H  HG     . SER   A  1 166 ? 69.986  -26.205 -10.334 1.00 52.32  ?  6964 SER   B HG     1 
ATOM   2617 N  N      . VAL   A  1 167 ? 71.536  -23.919 -6.493  1.00 41.66  ?  6965 VAL   B N      1 
ATOM   2618 C  CA     . VAL   A  1 167 ? 72.346  -23.186 -5.524  1.00 39.89  ?  6965 VAL   B CA     1 
ATOM   2619 C  C      . VAL   A  1 167 ? 73.195  -24.156 -4.709  1.00 39.54  ?  6965 VAL   B C      1 
ATOM   2620 O  O      . VAL   A  1 167 ? 72.851  -25.332 -4.546  1.00 38.39  ?  6965 VAL   B O      1 
ATOM   2621 C  CB     . VAL   A  1 167 ? 71.490  -22.315 -4.564  1.00 38.67  ?  6965 VAL   B CB     1 
ATOM   2622 C  CG1    . VAL   A  1 167 ? 70.513  -21.445 -5.327  1.00 40.62  ?  6965 VAL   B CG1    1 
ATOM   2623 C  CG2    . VAL   A  1 167 ? 70.762  -23.182 -3.538  1.00 39.61  ?  6965 VAL   B CG2    1 
ATOM   2624 H  H      . VAL   A  1 167 ? 71.155  -24.620 -6.171  1.00 50.51  ?  6965 VAL   B H      1 
ATOM   2625 H  HA     . VAL   A  1 167 ? 72.940  -22.607 -6.026  1.00 48.39  ?  6965 VAL   B HA     1 
ATOM   2626 H  HB     . VAL   A  1 167 ? 72.090  -21.724 -4.083  1.00 46.93  ?  6965 VAL   B HB     1 
ATOM   2627 H  HG11   . VAL   A  1 167 ? 70.052  -20.864 -4.702  1.00 49.26  ?  6965 VAL   B HG11   1 
ATOM   2628 H  HG12   . VAL   A  1 167 ? 71.002  -20.914 -5.975  1.00 49.26  ?  6965 VAL   B HG12   1 
ATOM   2629 H  HG13   . VAL   A  1 167 ? 69.873  -22.014 -5.783  1.00 49.26  ?  6965 VAL   B HG13   1 
ATOM   2630 H  HG21   . VAL   A  1 167 ? 70.055  -22.659 -3.128  1.00 48.05  ?  6965 VAL   B HG21   1 
ATOM   2631 H  HG22   . VAL   A  1 167 ? 70.384  -23.953 -3.988  1.00 48.05  ?  6965 VAL   B HG22   1 
ATOM   2632 H  HG23   . VAL   A  1 167 ? 71.395  -23.470 -2.862  1.00 48.05  ?  6965 VAL   B HG23   1 
ATOM   2633 N  N      . ALA   A  1 168 ? 74.314  -23.643 -4.187  1.00 41.96  ?  6966 ALA   B N      1 
ATOM   2634 C  CA     . ALA   A  1 168 ? 75.117  -24.330 -3.175  1.00 39.62  ?  6966 ALA   B CA     1 
ATOM   2635 C  C      . ALA   A  1 168 ? 75.665  -23.289 -2.205  1.00 39.74  ?  6966 ALA   B C      1 
ATOM   2636 O  O      . ALA   A  1 168 ? 76.416  -22.394 -2.609  1.00 40.28  ?  6966 ALA   B O      1 
ATOM   2637 C  CB     . ALA   A  1 168 ? 76.253  -25.132 -3.811  1.00 39.15  ?  6966 ALA   B CB     1 
ATOM   2638 H  H      . ALA   A  1 168 ? 74.636  -22.877 -4.411  1.00 50.88  ?  6966 ALA   B H      1 
ATOM   2639 H  HA     . ALA   A  1 168 ? 74.555  -24.946 -2.681  1.00 48.06  ?  6966 ALA   B HA     1 
ATOM   2640 H  HB1    . ALA   A  1 168 ? 76.758  -25.574 -3.110  1.00 47.50  ?  6966 ALA   B HB1    1 
ATOM   2641 H  HB2    . ALA   A  1 168 ? 75.876  -25.792 -4.413  1.00 47.50  ?  6966 ALA   B HB2    1 
ATOM   2642 H  HB3    . ALA   A  1 168 ? 76.830  -24.527 -4.303  1.00 47.50  ?  6966 ALA   B HB3    1 
ATOM   2643 N  N      . ILE   A  1 169 ? 75.337  -23.433 -0.922  1.00 41.40  ?  6967 ILE   B N      1 
ATOM   2644 C  CA     . ILE   A  1 169 ? 75.560  -22.398 0.088   1.00 39.23  ?  6967 ILE   B CA     1 
ATOM   2645 C  C      . ILE   A  1 169 ? 76.279  -23.046 1.260   1.00 37.05  ?  6967 ILE   B C      1 
ATOM   2646 O  O      . ILE   A  1 169 ? 75.735  -23.960 1.896   1.00 40.42  ?  6967 ILE   B O      1 
ATOM   2647 C  CB     . ILE   A  1 169 ? 74.242  -21.762 0.554   1.00 39.56  ?  6967 ILE   B CB     1 
ATOM   2648 C  CG1    . ILE   A  1 169 ? 73.314  -21.389 -0.617  1.00 40.93  ?  6967 ILE   B CG1    1 
ATOM   2649 C  CG2    . ILE   A  1 169 ? 74.503  -20.552 1.457   1.00 36.75  ?  6967 ILE   B CG2    1 
ATOM   2650 C  CD1    . ILE   A  1 169 ? 73.805  -20.274 -1.494  1.00 40.19  ?  6967 ILE   B CD1    1 
ATOM   2651 H  H      . ILE   A  1 169 ? 74.972  -24.143 -0.602  1.00 50.20  ?  6967 ILE   B H      1 
ATOM   2652 H  HA     . ILE   A  1 169 ? 76.125  -21.702 -0.284  1.00 47.60  ?  6967 ILE   B HA     1 
ATOM   2653 H  HB     . ILE   A  1 169 ? 73.778  -22.438 1.072   1.00 47.99  ?  6967 ILE   B HB     1 
ATOM   2654 H  HG12   . ILE   A  1 169 ? 73.203  -22.172 -1.180  1.00 49.64  ?  6967 ILE   B HG12   1 
ATOM   2655 H  HG13   . ILE   A  1 169 ? 72.457  -21.117 -0.254  1.00 49.64  ?  6967 ILE   B HG13   1 
ATOM   2656 H  HG21   . ILE   A  1 169 ? 73.664  -20.094 1.622   1.00 44.62  ?  6967 ILE   B HG21   1 
ATOM   2657 H  HG22   . ILE   A  1 169 ? 74.883  -20.859 2.295   1.00 44.62  ?  6967 ILE   B HG22   1 
ATOM   2658 H  HG23   . ILE   A  1 169 ? 75.124  -19.954 1.012   1.00 44.62  ?  6967 ILE   B HG23   1 
ATOM   2659 H  HD11   . ILE   A  1 169 ? 73.163  -20.127 -2.206  1.00 48.75  ?  6967 ILE   B HD11   1 
ATOM   2660 H  HD12   . ILE   A  1 169 ? 73.896  -19.469 -0.960  1.00 48.75  ?  6967 ILE   B HD12   1 
ATOM   2661 H  HD13   . ILE   A  1 169 ? 74.664  -20.522 -1.869  1.00 48.75  ?  6967 ILE   B HD13   1 
ATOM   2662 N  N      . LYS   A  1 170 ? 77.490  -22.580 1.555   1.00 41.51  ?  6968 LYS   B N      1 
ATOM   2663 C  CA     . LYS   A  1 170 ? 78.229  -23.146 2.681   1.00 42.97  ?  6968 LYS   B CA     1 
ATOM   2664 C  C      . LYS   A  1 170 ? 77.530  -22.838 3.994   1.00 36.43  ?  6968 LYS   B C      1 
ATOM   2665 O  O      . LYS   A  1 170 ? 77.106  -21.704 4.243   1.00 42.45  ?  6968 LYS   B O      1 
ATOM   2666 C  CB     . LYS   A  1 170 ? 79.670  -22.618 2.744   1.00 39.68  ?  6968 LYS   B CB     1 
ATOM   2667 C  CG     . LYS   A  1 170 ? 80.507  -23.136 3.978   1.00 37.78  ?  6968 LYS   B CG     1 
ATOM   2668 C  CD     . LYS   A  1 170 ? 81.521  -22.059 4.501   1.00 40.29  ?  6968 LYS   B CD     1 
ATOM   2669 C  CE     . LYS   A  1 170 ? 82.966  -22.581 4.567   1.00 46.52  ?  6968 LYS   B CE     1 
ATOM   2670 N  NZ     . LYS   A  1 170 ? 83.981  -21.562 4.808   1.00 65.37  ?  6968 LYS   B NZ     1 
ATOM   2671 H  H      . LYS   A  1 170 ? 77.897  -21.953 1.131   1.00 50.33  ?  6968 LYS   B H      1 
ATOM   2672 H  HA     . LYS   A  1 170 ? 78.269  -24.108 2.556   1.00 52.09  ?  6968 LYS   B HA     1 
ATOM   2673 H  HB2    . LYS   A  1 170 ? 80.135  -22.893 1.939   1.00 48.14  ?  6968 LYS   B HB2    1 
ATOM   2674 H  HB3    . LYS   A  1 170 ? 79.641  -21.650 2.796   1.00 48.14  ?  6968 LYS   B HB3    1 
ATOM   2675 H  HG2    . LYS   A  1 170 ? 79.903  -23.358 4.703   1.00 45.85  ?  6968 LYS   B HG2    1 
ATOM   2676 H  HG3    . LYS   A  1 170 ? 81.011  -23.922 3.714   1.00 45.85  ?  6968 LYS   B HG3    1 
ATOM   2677 H  HD2    . LYS   A  1 170 ? 81.506  -21.295 3.903   1.00 48.87  ?  6968 LYS   B HD2    1 
ATOM   2678 H  HD3    . LYS   A  1 170 ? 81.260  -21.787 5.394   1.00 48.87  ?  6968 LYS   B HD3    1 
ATOM   2679 H  HE2    . LYS   A  1 170 ? 83.027  -23.227 5.288   1.00 56.35  ?  6968 LYS   B HE2    1 
ATOM   2680 H  HE3    . LYS   A  1 170 ? 83.179  -23.007 3.721   1.00 56.35  ?  6968 LYS   B HE3    1 
ATOM   2681 H  HZ1    . LYS   A  1 170 ? 83.840  -21.173 5.596   1.00 78.97  ?  6968 LYS   B HZ1    1 
ATOM   2682 H  HZ2    . LYS   A  1 170 ? 84.791  -21.932 4.810   1.00 78.97  ?  6968 LYS   B HZ2    1 
ATOM   2683 H  HZ3    . LYS   A  1 170 ? 83.949  -20.943 4.170   1.00 78.97  ?  6968 LYS   B HZ3    1 
ATOM   2684 N  N      . ILE   A  1 171 ? 77.428  -23.861 4.842   1.00 43.09  ?  6969 ILE   B N      1 
ATOM   2685 C  CA     . ILE   A  1 171 ? 76.966  -23.709 6.208   1.00 40.44  ?  6969 ILE   B CA     1 
ATOM   2686 C  C      . ILE   A  1 171 ? 77.939  -24.447 7.121   1.00 38.08  ?  6969 ILE   B C      1 
ATOM   2687 O  O      . ILE   A  1 171 ? 78.815  -25.178 6.672   1.00 37.19  ?  6969 ILE   B O      1 
ATOM   2688 C  CB     . ILE   A  1 171 ? 75.537  -24.247 6.414   1.00 38.15  ?  6969 ILE   B CB     1 
ATOM   2689 C  CG1    . ILE   A  1 171 ? 75.416  -25.664 5.874   1.00 42.37  ?  6969 ILE   B CG1    1 
ATOM   2690 C  CG2    . ILE   A  1 171 ? 74.530  -23.376 5.680   1.00 39.68  ?  6969 ILE   B CG2    1 
ATOM   2691 C  CD1    . ILE   A  1 171 ? 74.401  -26.497 6.604   1.00 47.52  ?  6969 ILE   B CD1    1 
ATOM   2692 H  H      . ILE   A  1 171 ? 77.627  -24.672 4.637   1.00 52.23  ?  6969 ILE   B H      1 
ATOM   2693 H  HA     . ILE   A  1 171 ? 76.970  -22.767 6.439   1.00 49.05  ?  6969 ILE   B HA     1 
ATOM   2694 H  HB     . ILE   A  1 171 ? 75.359  -24.238 7.368   1.00 46.30  ?  6969 ILE   B HB     1 
ATOM   2695 H  HG12   . ILE   A  1 171 ? 75.151  -25.622 4.942   1.00 51.36  ?  6969 ILE   B HG12   1 
ATOM   2696 H  HG13   . ILE   A  1 171 ? 76.276  -26.105 5.955   1.00 51.36  ?  6969 ILE   B HG13   1 
ATOM   2697 H  HG21   . ILE   A  1 171 ? 73.645  -23.758 5.788   1.00 48.14  ?  6969 ILE   B HG21   1 
ATOM   2698 H  HG22   . ILE   A  1 171 ? 74.552  -22.482 6.056   1.00 48.14  ?  6969 ILE   B HG22   1 
ATOM   2699 H  HG23   . ILE   A  1 171 ? 74.765  -23.346 4.740   1.00 48.14  ?  6969 ILE   B HG23   1 
ATOM   2700 H  HD11   . ILE   A  1 171 ? 74.382  -27.385 6.214   1.00 57.55  ?  6969 ILE   B HD11   1 
ATOM   2701 H  HD12   . ILE   A  1 171 ? 74.652  -26.553 7.539   1.00 57.55  ?  6969 ILE   B HD12   1 
ATOM   2702 H  HD13   . ILE   A  1 171 ? 73.530  -26.080 6.520   1.00 57.55  ?  6969 ILE   B HD13   1 
ATOM   2703 N  N      . THR   A  1 172 ? 77.784  -24.231 8.426   1.00 43.57  ?  6970 THR   B N      1 
ATOM   2704 C  CA     . THR   A  1 172 ? 78.512  -25.011 9.419   1.00 41.16  ?  6970 THR   B CA     1 
ATOM   2705 C  C      . THR   A  1 172 ? 77.538  -25.325 10.544  1.00 37.79  ?  6970 THR   B C      1 
ATOM   2706 O  O      . THR   A  1 172 ? 76.348  -24.990 10.472  1.00 39.57  ?  6970 THR   B O      1 
ATOM   2707 C  CB     . THR   A  1 172 ? 79.748  -24.287 9.966   1.00 37.90  ?  6970 THR   B CB     1 
ATOM   2708 O  OG1    . THR   A  1 172 ? 79.341  -23.115 10.674  1.00 41.37  ?  6970 THR   B OG1    1 
ATOM   2709 C  CG2    . THR   A  1 172 ? 80.707  -23.917 8.870   1.00 44.48  ?  6970 THR   B CG2    1 
ATOM   2710 H  H      . THR   A  1 172 ? 77.261  -23.636 8.761   1.00 52.80  ?  6970 THR   B H      1 
ATOM   2711 H  HA     . THR   A  1 172 ? 78.815  -25.820 8.979   1.00 49.91  ?  6970 THR   B HA     1 
ATOM   2712 H  HB     . THR   A  1 172 ? 80.220  -24.883 10.568  1.00 46.00  ?  6970 THR   B HB     1 
ATOM   2713 H  HG1    . THR   A  1 172 ? 80.008  -22.745 11.025  1.00 50.16  ?  6970 THR   B HG1    1 
ATOM   2714 H  HG21   . THR   A  1 172 ? 81.496  -23.499 9.247   1.00 53.89  ?  6970 THR   B HG21   1 
ATOM   2715 H  HG22   . THR   A  1 172 ? 80.975  -24.711 8.381   1.00 53.89  ?  6970 THR   B HG22   1 
ATOM   2716 H  HG23   . THR   A  1 172 ? 80.285  -23.297 8.255   1.00 53.89  ?  6970 THR   B HG23   1 
ATOM   2717 N  N      . GLU   A  1 173 ? 78.051  -25.954 11.605  1.00 44.21  ?  6971 GLU   B N      1 
ATOM   2718 C  CA     . GLU   A  1 173 ? 77.244  -26.137 12.810  1.00 41.14  ?  6971 GLU   B CA     1 
ATOM   2719 C  C      . GLU   A  1 173 ? 76.642  -24.808 13.256  1.00 36.39  ?  6971 GLU   B C      1 
ATOM   2720 O  O      . GLU   A  1 173 ? 75.451  -24.734 13.575  1.00 40.65  ?  6971 GLU   B O      1 
ATOM   2721 C  CB     . GLU   A  1 173 ? 78.089  -26.758 13.932  1.00 41.06  ?  6971 GLU   B CB     1 
ATOM   2722 C  CG     . GLU   A  1 173 ? 77.403  -26.672 15.312  1.00 40.51  ?  6971 GLU   B CG     1 
ATOM   2723 C  CD     . GLU   A  1 173 ? 78.217  -27.258 16.450  1.00 44.49  ?  6971 GLU   B CD     1 
ATOM   2724 O  OE1    . GLU   A  1 173 ? 79.441  -27.430 16.304  1.00 43.40  ?  6971 GLU   B OE1    1 
ATOM   2725 O  OE2    . GLU   A  1 173 ? 77.624  -27.547 17.510  1.00 47.31  ?  6971 GLU   B OE2    1 
ATOM   2726 H  H      . GLU   A  1 173 ? 78.847  -26.277 11.651  1.00 53.58  ?  6971 GLU   B H      1 
ATOM   2727 H  HA     . GLU   A  1 173 ? 76.521  -26.754 12.615  1.00 49.89  ?  6971 GLU   B HA     1 
ATOM   2728 H  HB2    . GLU   A  1 173 ? 78.242  -27.694 13.731  1.00 49.80  ?  6971 GLU   B HB2    1 
ATOM   2729 H  HB3    . GLU   A  1 173 ? 78.935  -26.287 13.988  1.00 49.80  ?  6971 GLU   B HB3    1 
ATOM   2730 H  HG2    . GLU   A  1 173 ? 77.239  -25.739 15.519  1.00 49.13  ?  6971 GLU   B HG2    1 
ATOM   2731 H  HG3    . GLU   A  1 173 ? 76.564  -27.156 15.272  1.00 49.13  ?  6971 GLU   B HG3    1 
ATOM   2732 N  N      . HIS   A  1 174 ? 77.449  -23.742 13.269  1.00 38.61  ?  6972 HIS   B N      1 
ATOM   2733 C  CA     . HIS   A  1 174 ? 77.001  -22.461 13.788  1.00 39.25  ?  6972 HIS   B CA     1 
ATOM   2734 C  C      . HIS   A  1 174 ? 76.635  -21.462 12.700  1.00 40.72  ?  6972 HIS   B C      1 
ATOM   2735 O  O      . HIS   A  1 174 ? 75.881  -20.524 12.983  1.00 42.28  ?  6972 HIS   B O      1 
ATOM   2736 C  CB     . HIS   A  1 174 ? 78.064  -21.834 14.708  1.00 42.81  ?  6972 HIS   B CB     1 
ATOM   2737 C  CG     . HIS   A  1 174 ? 78.280  -22.613 15.970  1.00 44.63  ?  6972 HIS   B CG     1 
ATOM   2738 N  ND1    . HIS   A  1 174 ? 77.552  -22.388 17.118  1.00 51.54  ?  6972 HIS   B ND1    1 
ATOM   2739 C  CD2    . HIS   A  1 174 ? 79.138  -23.619 16.261  1.00 46.44  ?  6972 HIS   B CD2    1 
ATOM   2740 C  CE1    . HIS   A  1 174 ? 77.935  -23.239 18.052  1.00 53.40  ?  6972 HIS   B CE1    1 
ATOM   2741 N  NE2    . HIS   A  1 174 ? 78.905  -23.990 17.562  1.00 49.69  ?  6972 HIS   B NE2    1 
ATOM   2742 H  H      . HIS   A  1 174 ? 78.260  -23.743 12.982  1.00 46.86  ?  6972 HIS   B H      1 
ATOM   2743 H  HA     . HIS   A  1 174 ? 76.210  -22.616 14.327  1.00 47.62  ?  6972 HIS   B HA     1 
ATOM   2744 H  HB2    . HIS   A  1 174 ? 78.908  -21.795 14.233  1.00 51.89  ?  6972 HIS   B HB2    1 
ATOM   2745 H  HB3    . HIS   A  1 174 ? 77.780  -20.940 14.954  1.00 51.89  ?  6972 HIS   B HB3    1 
ATOM   2746 H  HD1    . HIS   A  1 174 ? 76.944  -21.788 17.211  1.00 62.37  ?  6972 HIS   B HD1    1 
ATOM   2747 H  HD2    . HIS   A  1 174 ? 79.769  -23.991 15.687  1.00 56.25  ?  6972 HIS   B HD2    1 
ATOM   2748 H  HE1    . HIS   A  1 174 ? 77.581  -23.300 18.910  1.00 64.61  ?  6972 HIS   B HE1    1 
ATOM   2749 N  N      . SER   A  1 175 ? 77.131  -21.632 11.472  1.00 40.75  ?  6973 SER   B N      1 
ATOM   2750 C  CA     . SER   A  1 175 ? 76.788  -20.722 10.375  1.00 40.82  ?  6973 SER   B CA     1 
ATOM   2751 C  C      . SER   A  1 175 ? 75.663  -21.356 9.563   1.00 37.22  ?  6973 SER   B C      1 
ATOM   2752 O  O      . SER   A  1 175 ? 75.896  -22.128 8.629   1.00 42.51  ?  6973 SER   B O      1 
ATOM   2753 C  CB     . SER   A  1 175 ? 78.007  -20.409 9.511   1.00 42.92  ?  6973 SER   B CB     1 
ATOM   2754 O  OG     . SER   A  1 175 ? 77.721  -19.325 8.635   1.00 43.34  ?  6973 SER   B OG     1 
ATOM   2755 H  H      . SER   A  1 175 ? 77.667  -22.266 11.249  1.00 49.42  ?  6973 SER   B H      1 
ATOM   2756 H  HA     . SER   A  1 175 ? 76.460  -19.891 10.752  1.00 49.50  ?  6973 SER   B HA     1 
ATOM   2757 H  HB2    . SER   A  1 175 ? 78.751  -20.166 10.085  1.00 52.03  ?  6973 SER   B HB2    1 
ATOM   2758 H  HB3    . SER   A  1 175 ? 78.235  -21.191 8.986   1.00 52.03  ?  6973 SER   B HB3    1 
ATOM   2759 H  HG     . SER   A  1 175 ? 78.399  -19.141 8.175   1.00 52.53  ?  6973 SER   B HG     1 
ATOM   2760 N  N      . TRP   A  1 176 ? 74.428  -21.026 9.926   1.00 38.27  ?  6974 TRP   B N      1 
ATOM   2761 C  CA     . TRP   A  1 176 ? 73.259  -21.601 9.271   1.00 39.17  ?  6974 TRP   B CA     1 
ATOM   2762 C  C      . TRP   A  1 176 ? 72.075  -20.671 9.491   1.00 39.67  ?  6974 TRP   B C      1 
ATOM   2763 O  O      . TRP   A  1 176 ? 72.111  -19.785 10.344  1.00 42.13  ?  6974 TRP   B O      1 
ATOM   2764 C  CB     . TRP   A  1 176 ? 72.962  -22.995 9.819   1.00 39.39  ?  6974 TRP   B CB     1 
ATOM   2765 C  CG     . TRP   A  1 176 ? 72.507  -22.940 11.232  1.00 40.31  ?  6974 TRP   B CG     1 
ATOM   2766 C  CD1    . TRP   A  1 176 ? 73.281  -22.756 12.336  1.00 39.55  ?  6974 TRP   B CD1    1 
ATOM   2767 C  CD2    . TRP   A  1 176 ? 71.160  -23.038 11.693  1.00 37.82  ?  6974 TRP   B CD2    1 
ATOM   2768 N  NE1    . TRP   A  1 176 ? 72.501  -22.741 13.463  1.00 44.87  ?  6974 TRP   B NE1    1 
ATOM   2769 C  CE2    . TRP   A  1 176 ? 71.191  -22.917 13.096  1.00 44.22  ?  6974 TRP   B CE2    1 
ATOM   2770 C  CE3    . TRP   A  1 176 ? 69.933  -23.222 11.053  1.00 41.02  ?  6974 TRP   B CE3    1 
ATOM   2771 C  CZ2    . TRP   A  1 176 ? 70.037  -22.979 13.877  1.00 37.77  ?  6974 TRP   B CZ2    1 
ATOM   2772 C  CZ3    . TRP   A  1 176 ? 68.788  -23.280 11.817  1.00 39.86  ?  6974 TRP   B CZ3    1 
ATOM   2773 C  CH2    . TRP   A  1 176 ? 68.845  -23.162 13.222  1.00 40.68  ?  6974 TRP   B CH2    1 
ATOM   2774 H  H      . TRP   A  1 176 ? 74.240  -20.468 10.553  1.00 46.44  ?  6974 TRP   B H      1 
ATOM   2775 H  HA     . TRP   A  1 176 ? 73.422  -21.666 8.317   1.00 47.53  ?  6974 TRP   B HA     1 
ATOM   2776 H  HB2    . TRP   A  1 176 ? 72.262  -23.405 9.288   1.00 47.79  ?  6974 TRP   B HB2    1 
ATOM   2777 H  HB3    . TRP   A  1 176 ? 73.768  -23.533 9.779   1.00 47.79  ?  6974 TRP   B HB3    1 
ATOM   2778 H  HD1    . TRP   A  1 176 ? 74.206  -22.654 12.327  1.00 47.98  ?  6974 TRP   B HD1    1 
ATOM   2779 H  HE1    . TRP   A  1 176 ? 72.786  -22.639 14.268  1.00 54.37  ?  6974 TRP   B HE1    1 
ATOM   2780 H  HE3    . TRP   A  1 176 ? 69.889  -23.303 10.128  1.00 49.74  ?  6974 TRP   B HE3    1 
ATOM   2781 H  HZ2    . TRP   A  1 176 ? 70.074  -22.899 14.803  1.00 45.84  ?  6974 TRP   B HZ2    1 
ATOM   2782 H  HZ3    . TRP   A  1 176 ? 67.966  -23.400 11.401  1.00 48.35  ?  6974 TRP   B HZ3    1 
ATOM   2783 H  HH2    . TRP   A  1 176 ? 68.058  -23.209 13.715  1.00 49.33  ?  6974 TRP   B HH2    1 
ATOM   2784 N  N      . ASN   A  1 177 ? 71.002  -20.919 8.742   1.00 41.73  ?  6975 ASN   B N      1 
ATOM   2785 C  CA     . ASN   A  1 177 ? 69.821  -20.071 8.745   1.00 39.83  ?  6975 ASN   B CA     1 
ATOM   2786 C  C      . ASN   A  1 177 ? 68.620  -20.951 8.439   1.00 44.88  ?  6975 ASN   B C      1 
ATOM   2787 O  O      . ASN   A  1 177 ? 68.672  -21.785 7.527   1.00 44.73  ?  6975 ASN   B O      1 
ATOM   2788 C  CB     . ASN   A  1 177 ? 69.938  -18.949 7.707   1.00 40.65  ?  6975 ASN   B CB     1 
ATOM   2789 C  CG     . ASN   A  1 177 ? 68.714  -18.072 7.656   1.00 35.70  ?  6975 ASN   B CG     1 
ATOM   2790 O  OD1    . ASN   A  1 177 ? 67.788  -18.329 6.895   1.00 43.33  ?  6975 ASN   B OD1    1 
ATOM   2791 N  ND2    . ASN   A  1 177 ? 68.719  -17.008 8.443   1.00 48.58  ?  6975 ASN   B ND2    1 
ATOM   2792 H  H      . ASN   A  1 177 ? 70.936  -21.592 8.210   1.00 50.59  ?  6975 ASN   B H      1 
ATOM   2793 H  HA     . ASN   A  1 177 ? 69.699  -19.659 9.614   1.00 48.32  ?  6975 ASN   B HA     1 
ATOM   2794 H  HB2    . ASN   A  1 177 ? 70.698  -18.390 7.931   1.00 49.30  ?  6975 ASN   B HB2    1 
ATOM   2795 H  HB3    . ASN   A  1 177 ? 70.063  -19.342 6.829   1.00 49.30  ?  6975 ASN   B HB3    1 
ATOM   2796 H  HD21   . ASN   A  1 177 ? 68.044  -16.476 8.450   1.00 58.82  ?  6975 ASN   B HD21   1 
ATOM   2797 H  HD22   . ASN   A  1 177 ? 69.398  -16.849 8.946   1.00 58.82  ?  6975 ASN   B HD22   1 
ATOM   2798 N  N      . ALA   A  1 178 ? 67.543  -20.774 9.215   1.00 41.32  ?  6976 ALA   B N      1 
ATOM   2799 C  CA     . ALA   A  1 178 ? 66.398  -21.673 9.107   1.00 37.17  ?  6976 ALA   B CA     1 
ATOM   2800 C  C      . ALA   A  1 178 ? 65.589  -21.422 7.840   1.00 38.44  ?  6976 ALA   B C      1 
ATOM   2801 O  O      . ALA   A  1 178 ? 65.029  -22.366 7.271   1.00 38.23  ?  6976 ALA   B O      1 
ATOM   2802 C  CB     . ALA   A  1 178 ? 65.505  -21.564 10.340  1.00 40.94  ?  6976 ALA   B CB     1 
ATOM   2803 H  H      . ALA   A  1 178 ? 67.455  -20.149 9.800   1.00 50.10  ?  6976 ALA   B H      1 
ATOM   2804 H  HA     . ALA   A  1 178 ? 66.729  -22.584 9.073   1.00 45.13  ?  6976 ALA   B HA     1 
ATOM   2805 H  HB1    . ALA   A  1 178 ? 64.748  -22.162 10.236  1.00 49.65  ?  6976 ALA   B HB1    1 
ATOM   2806 H  HB2    . ALA   A  1 178 ? 66.017  -21.814 11.125  1.00 49.65  ?  6976 ALA   B HB2    1 
ATOM   2807 H  HB3    . ALA   A  1 178 ? 65.194  -20.649 10.425  1.00 49.65  ?  6976 ALA   B HB3    1 
ATOM   2808 N  N      . ASP   A  1 179 ? 65.494  -20.171 7.387   1.00 43.87  ?  6977 ASP   B N      1 
ATOM   2809 C  CA     . ASP   A  1 179 ? 64.738  -19.900 6.172   1.00 42.88  ?  6977 ASP   B CA     1 
ATOM   2810 C  C      . ASP   A  1 179 ? 65.435  -20.473 4.954   1.00 39.55  ?  6977 ASP   B C      1 
ATOM   2811 O  O      . ASP   A  1 179 ? 64.772  -20.822 3.975   1.00 44.79  ?  6977 ASP   B O      1 
ATOM   2812 C  CB     . ASP   A  1 179 ? 64.542  -18.404 5.989   1.00 40.86  ?  6977 ASP   B CB     1 
ATOM   2813 C  CG     . ASP   A  1 179 ? 63.310  -17.895 6.680   1.00 60.08  ?  6977 ASP   B CG     1 
ATOM   2814 O  OD1    . ASP   A  1 179 ? 62.321  -18.648 6.781   1.00 62.41  ?  6977 ASP   B OD1    1 
ATOM   2815 O  OD2    . ASP   A  1 179 ? 63.337  -16.745 7.152   1.00 66.19  ?  6977 ASP   B OD2    1 
ATOM   2816 H  H      . ASP   A  1 179 ? 65.851  -19.481 7.757   1.00 53.16  ?  6977 ASP   B H      1 
ATOM   2817 H  HA     . ASP   A  1 179 ? 63.862  -20.309 6.256   1.00 51.97  ?  6977 ASP   B HA     1 
ATOM   2818 H  HB2    . ASP   A  1 179 ? 65.308  -17.937 6.358   1.00 49.55  ?  6977 ASP   B HB2    1 
ATOM   2819 H  HB3    . ASP   A  1 179 ? 64.459  -18.208 5.043   1.00 49.55  ?  6977 ASP   B HB3    1 
ATOM   2820 N  N      . LEU   A  1 180 ? 66.770  -20.528 4.972   1.00 42.34  ?  6978 LEU   B N      1 
ATOM   2821 C  CA     . LEU   A  1 180 ? 67.494  -21.130 3.860   1.00 45.82  ?  6978 LEU   B CA     1 
ATOM   2822 C  C      . LEU   A  1 180 ? 67.123  -22.600 3.719   1.00 42.78  ?  6978 LEU   B C      1 
ATOM   2823 O  O      . LEU   A  1 180 ? 66.855  -23.093 2.611   1.00 41.53  ?  6978 LEU   B O      1 
ATOM   2824 C  CB     . LEU   A  1 180 ? 68.997  -20.956 4.072   1.00 37.74  ?  6978 LEU   B CB     1 
ATOM   2825 C  CG     . LEU   A  1 180 ? 69.827  -21.593 2.962   1.00 37.75  ?  6978 LEU   B CG     1 
ATOM   2826 C  CD1    . LEU   A  1 180 ? 69.537  -20.911 1.632   1.00 40.97  ?  6978 LEU   B CD1    1 
ATOM   2827 C  CD2    . LEU   A  1 180 ? 71.313  -21.486 3.302   1.00 41.13  ?  6978 LEU   B CD2    1 
ATOM   2828 H  H      . LEU   A  1 180 ? 67.268  -20.228 5.607   1.00 51.34  ?  6978 LEU   B H      1 
ATOM   2829 H  HA     . LEU   A  1 180 ? 67.258  -20.681 3.033   1.00 55.50  ?  6978 LEU   B HA     1 
ATOM   2830 H  HB2    . LEU   A  1 180 ? 69.204  -20.008 4.096   1.00 45.81  ?  6978 LEU   B HB2    1 
ATOM   2831 H  HB3    . LEU   A  1 180 ? 69.248  -21.372 4.911   1.00 45.81  ?  6978 LEU   B HB3    1 
ATOM   2832 H  HG     . LEU   A  1 180 ? 69.595  -22.531 2.877   1.00 45.82  ?  6978 LEU   B HG     1 
ATOM   2833 H  HD11   . LEU   A  1 180 ? 70.194  -21.199 0.979   1.00 49.69  ?  6978 LEU   B HD11   1 
ATOM   2834 H  HD12   . LEU   A  1 180 ? 68.647  -21.159 1.337   1.00 49.69  ?  6978 LEU   B HD12   1 
ATOM   2835 H  HD13   . LEU   A  1 180 ? 69.590  -19.950 1.752   1.00 49.69  ?  6978 LEU   B HD13   1 
ATOM   2836 H  HD21   . LEU   A  1 180 ? 71.830  -21.901 2.594   1.00 49.88  ?  6978 LEU   B HD21   1 
ATOM   2837 H  HD22   . LEU   A  1 180 ? 71.552  -20.550 3.382   1.00 49.88  ?  6978 LEU   B HD22   1 
ATOM   2838 H  HD23   . LEU   A  1 180 ? 71.478  -21.942 4.143   1.00 49.88  ?  6978 LEU   B HD23   1 
ATOM   2839 N  N      . TYR   A  1 181 ? 67.120  -23.324 4.840   1.00 39.60  ?  6979 TYR   B N      1 
ATOM   2840 C  CA     . TYR   A  1 181 ? 66.648  -24.706 4.809   1.00 42.01  ?  6979 TYR   B CA     1 
ATOM   2841 C  C      . TYR   A  1 181 ? 65.218  -24.778 4.290   1.00 35.08  ?  6979 TYR   B C      1 
ATOM   2842 O  O      . TYR   A  1 181 ? 64.875  -25.652 3.484   1.00 40.54  ?  6979 TYR   B O      1 
ATOM   2843 C  CB     . TYR   A  1 181 ? 66.694  -25.344 6.201   1.00 40.50  ?  6979 TYR   B CB     1 
ATOM   2844 C  CG     . TYR   A  1 181 ? 68.005  -25.914 6.635   1.00 38.48  ?  6979 TYR   B CG     1 
ATOM   2845 C  CD1    . TYR   A  1 181 ? 68.427  -27.133 6.134   1.00 42.30  ?  6979 TYR   B CD1    1 
ATOM   2846 C  CD2    . TYR   A  1 181 ? 68.781  -25.284 7.599   1.00 37.43  ?  6979 TYR   B CD2    1 
ATOM   2847 C  CE1    . TYR   A  1 181 ? 69.609  -27.678 6.531   1.00 39.79  ?  6979 TYR   B CE1    1 
ATOM   2848 C  CE2    . TYR   A  1 181 ? 69.964  -25.820 8.000   1.00 38.44  ?  6979 TYR   B CE2    1 
ATOM   2849 C  CZ     . TYR   A  1 181 ? 70.369  -27.018 7.468   1.00 38.92  ?  6979 TYR   B CZ     1 
ATOM   2850 O  OH     . TYR   A  1 181 ? 71.555  -27.567 7.867   1.00 39.72  ?  6979 TYR   B OH     1 
ATOM   2851 H  H      . TYR   A  1 181 ? 67.381  -23.046 5.611   1.00 48.04  ?  6979 TYR   B H      1 
ATOM   2852 H  HA     . TYR   A  1 181 ? 67.241  -25.200 4.222   1.00 50.94  ?  6979 TYR   B HA     1 
ATOM   2853 H  HB2    . TYR   A  1 181 ? 66.451  -24.665 6.850   1.00 49.12  ?  6979 TYR   B HB2    1 
ATOM   2854 H  HB3    . TYR   A  1 181 ? 66.049  -26.068 6.221   1.00 49.12  ?  6979 TYR   B HB3    1 
ATOM   2855 H  HD1    . TYR   A  1 181 ? 67.897  -27.585 5.518   1.00 51.29  ?  6979 TYR   B HD1    1 
ATOM   2856 H  HD2    . TYR   A  1 181 ? 68.488  -24.485 7.975   1.00 45.43  ?  6979 TYR   B HD2    1 
ATOM   2857 H  HE1    . TYR   A  1 181 ? 69.899  -28.487 6.174   1.00 48.26  ?  6979 TYR   B HE1    1 
ATOM   2858 H  HE2    . TYR   A  1 181 ? 70.493  -25.380 8.627   1.00 46.65  ?  6979 TYR   B HE2    1 
ATOM   2859 H  HH     . TYR   A  1 181 ? 72.099  -26.959 8.069   1.00 48.19  ?  6979 TYR   B HH     1 
ATOM   2860 N  N      . LYS   A  1 182 ? 64.344  -23.929 4.831   1.00 41.94  ?  6980 LYS   B N      1 
ATOM   2861 C  CA     . LYS   A  1 182 ? 62.970  -23.876 4.359   1.00 37.18  ?  6980 LYS   B CA     1 
ATOM   2862 C  C      . LYS   A  1 182 ? 62.931  -23.671 2.854   1.00 39.12  ?  6980 LYS   B C      1 
ATOM   2863 O  O      . LYS   A  1 182 ? 62.145  -24.312 2.149   1.00 42.86  ?  6980 LYS   B O      1 
ATOM   2864 C  CB     . LYS   A  1 182 ? 62.226  -22.758 5.076   1.00 45.66  ?  6980 LYS   B CB     1 
ATOM   2865 C  CG     . LYS   A  1 182 ? 60.791  -22.631 4.710   1.00 50.11  ?  6980 LYS   B CG     1 
ATOM   2866 C  CD     . LYS   A  1 182 ? 60.131  -21.732 5.717   1.00 60.28  ?  6980 LYS   B CD     1 
ATOM   2867 C  CE     . LYS   A  1 182 ? 58.750  -21.347 5.286   1.00 75.37  ?  6980 LYS   B CE     1 
ATOM   2868 N  NZ     . LYS   A  1 182 ? 58.602  -19.881 5.303   1.00 93.01  ?  6980 LYS   B NZ     1 
ATOM   2869 H  H      . LYS   A  1 182 ? 64.523  -23.378 5.467   1.00 50.84  ?  6980 LYS   B H      1 
ATOM   2870 H  HA     . LYS   A  1 182 ? 62.522  -24.712 4.563   1.00 45.14  ?  6980 LYS   B HA     1 
ATOM   2871 H  HB2    . LYS   A  1 182 ? 62.270  -22.922 6.031   1.00 55.32  ?  6980 LYS   B HB2    1 
ATOM   2872 H  HB3    . LYS   A  1 182 ? 62.657  -21.916 4.863   1.00 55.32  ?  6980 LYS   B HB3    1 
ATOM   2873 H  HG2    . LYS   A  1 182 ? 60.704  -22.239 3.827   1.00 60.66  ?  6980 LYS   B HG2    1 
ATOM   2874 H  HG3    . LYS   A  1 182 ? 60.362  -23.501 4.730   1.00 60.66  ?  6980 LYS   B HG3    1 
ATOM   2875 H  HD2    . LYS   A  1 182 ? 60.067  -22.194 6.568   1.00 72.86  ?  6980 LYS   B HD2    1 
ATOM   2876 H  HD3    . LYS   A  1 182 ? 60.655  -20.922 5.818   1.00 72.86  ?  6980 LYS   B HD3    1 
ATOM   2877 H  HE2    . LYS   A  1 182 ? 58.590  -21.665 4.384   1.00 90.96  ?  6980 LYS   B HE2    1 
ATOM   2878 H  HE3    . LYS   A  1 182 ? 58.099  -21.732 5.894   1.00 90.96  ?  6980 LYS   B HE3    1 
ATOM   2879 H  HZ1    . LYS   A  1 182 ? 57.804  -19.652 4.982   1.00 112.13 ?  6980 LYS   B HZ1    1 
ATOM   2880 H  HZ2    . LYS   A  1 182 ? 58.676  -19.577 6.136   1.00 112.13 ?  6980 LYS   B HZ2    1 
ATOM   2881 H  HZ3    . LYS   A  1 182 ? 59.233  -19.505 4.801   1.00 112.13 ?  6980 LYS   B HZ3    1 
ATOM   2882 N  N      A LEU   A  1 183 ? 63.809  -22.807 2.344   0.49 42.54  ?  6981 LEU   B N      1 
ATOM   2883 N  N      B LEU   A  1 183 ? 63.780  -22.780 2.343   0.51 42.69  ?  6981 LEU   B N      1 
ATOM   2884 C  CA     A LEU   A  1 183 ? 63.857  -22.493 0.923   0.49 40.08  ?  6981 LEU   B CA     1 
ATOM   2885 C  CA     B LEU   A  1 183 ? 63.813  -22.522 0.909   0.51 39.89  ?  6981 LEU   B CA     1 
ATOM   2886 C  C      A LEU   A  1 183 ? 64.352  -23.661 0.079   0.49 38.13  ?  6981 LEU   B C      1 
ATOM   2887 C  C      B LEU   A  1 183 ? 64.174  -23.771 0.122   0.51 38.18  ?  6981 LEU   B C      1 
ATOM   2888 O  O      A LEU   A  1 183 ? 64.159  -23.650 -1.141  0.49 39.00  ?  6981 LEU   B O      1 
ATOM   2889 O  O      B LEU   A  1 183 ? 63.698  -23.949 -1.003  0.51 40.12  ?  6981 LEU   B O      1 
ATOM   2890 C  CB     A LEU   A  1 183 ? 64.769  -21.293 0.707   0.49 40.18  ?  6981 LEU   B CB     1 
ATOM   2891 C  CB     B LEU   A  1 183 ? 64.811  -21.410 0.605   0.51 40.25  ?  6981 LEU   B CB     1 
ATOM   2892 C  CG     A LEU   A  1 183 ? 64.940  -20.678 -0.673  0.49 38.63  ?  6981 LEU   B CG     1 
ATOM   2893 C  CG     B LEU   A  1 183 ? 64.271  -19.984 0.545   0.51 43.90  ?  6981 LEU   B CG     1 
ATOM   2894 C  CD1    A LEU   A  1 183 ? 63.633  -20.230 -1.213  0.49 45.38  ?  6981 LEU   B CD1    1 
ATOM   2895 C  CD1    B LEU   A  1 183 ? 65.434  -19.051 0.265   0.51 44.68  ?  6981 LEU   B CD1    1 
ATOM   2896 C  CD2    A LEU   A  1 183 ? 65.933  -19.526 -0.525  0.49 42.67  ?  6981 LEU   B CD2    1 
ATOM   2897 C  CD2    B LEU   A  1 183 ? 63.201  -19.857 -0.497  0.51 47.54  ?  6981 LEU   B CD2    1 
ATOM   2898 H  H      A LEU   A  1 183 ? 64.396  -22.385 2.809   0.49 51.57  ?  6981 LEU   B H      1 
ATOM   2899 H  H      B LEU   A  1 183 ? 64.340  -22.316 2.801   0.51 51.75  ?  6981 LEU   B H      1 
ATOM   2900 H  HA     A LEU   A  1 183 ? 62.962  -22.270 0.621   0.49 48.62  ?  6981 LEU   B HA     1 
ATOM   2901 H  HA     B LEU   A  1 183 ? 62.933  -22.230 0.625   0.51 48.38  ?  6981 LEU   B HA     1 
ATOM   2902 H  HB2    A LEU   A  1 183 ? 64.437  -20.580 1.276   0.49 48.74  ?  6981 LEU   B HB2    1 
ATOM   2903 H  HB2    B LEU   A  1 183 ? 65.492  -21.425 1.295   0.51 48.82  ?  6981 LEU   B HB2    1 
ATOM   2904 H  HB3    A LEU   A  1 183 ? 65.657  -21.558 0.991   0.49 48.74  ?  6981 LEU   B HB3    1 
ATOM   2905 H  HB3    B LEU   A  1 183 ? 65.211  -21.597 -0.259  0.51 48.82  ?  6981 LEU   B HB3    1 
ATOM   2906 H  HG     A LEU   A  1 183 ? 65.282  -21.318 -1.317  0.49 46.88  ?  6981 LEU   B HG     1 
ATOM   2907 H  HG     B LEU   A  1 183 ? 63.859  -19.739 1.388   0.51 53.21  ?  6981 LEU   B HG     1 
ATOM   2908 H  HD11   A LEU   A  1 183 ? 63.780  -19.767 -2.053  0.49 54.98  ?  6981 LEU   B HD11   1 
ATOM   2909 H  HD11   B LEU   A  1 183 ? 65.105  -18.140 0.223   0.51 54.14  ?  6981 LEU   B HD11   1 
ATOM   2910 H  HD12   A LEU   A  1 183 ? 63.069  -21.006 -1.358  0.49 54.98  ?  6981 LEU   B HD12   1 
ATOM   2911 H  HD12   B LEU   A  1 183 ? 66.085  -19.135 0.980   0.51 54.14  ?  6981 LEU   B HD12   1 
ATOM   2912 H  HD13   A LEU   A  1 183 ? 63.215  -19.632 -0.574  0.49 54.98  ?  6981 LEU   B HD13   1 
ATOM   2913 H  HD13   B LEU   A  1 183 ? 65.840  -19.296 -0.581  0.51 54.14  ?  6981 LEU   B HD13   1 
ATOM   2914 H  HD21   A LEU   A  1 183 ? 65.932  -19.001 -1.341  0.49 51.73  ?  6981 LEU   B HD21   1 
ATOM   2915 H  HD21   B LEU   A  1 183 ? 63.097  -18.922 -0.731  0.51 57.57  ?  6981 LEU   B HD21   1 
ATOM   2916 H  HD22   A LEU   A  1 183 ? 65.664  -18.972 0.225   0.49 51.73  ?  6981 LEU   B HD22   1 
ATOM   2917 H  HD22   B LEU   A  1 183 ? 63.461  -20.367 -1.281  0.51 57.57  ?  6981 LEU   B HD22   1 
ATOM   2918 H  HD23   A LEU   A  1 183 ? 66.818  -19.890 -0.367  0.49 51.73  ?  6981 LEU   B HD23   1 
ATOM   2919 H  HD23   B LEU   A  1 183 ? 62.368  -20.203 -0.139  0.51 57.57  ?  6981 LEU   B HD23   1 
ATOM   2920 N  N      . MET   A  1 184 ? 65.002  -24.655 0.695   1.00 41.92  ?  6982 MET   B N      1 
ATOM   2921 C  CA     . MET   A  1 184 ? 65.406  -25.850 -0.040  1.00 37.56  ?  6982 MET   B CA     1 
ATOM   2922 C  C      . MET   A  1 184 ? 64.176  -26.623 -0.493  1.00 38.46  ?  6982 MET   B C      1 
ATOM   2923 O  O      . MET   A  1 184 ? 64.218  -27.329 -1.509  1.00 38.96  ?  6982 MET   B O      1 
ATOM   2924 C  CB     . MET   A  1 184 ? 66.300  -26.772 0.801   1.00 36.76  ?  6982 MET   B CB     1 
ATOM   2925 C  CG     . MET   A  1 184 ? 67.624  -26.167 1.189   1.00 37.60  ?  6982 MET   B CG     1 
ATOM   2926 S  SD     . MET   A  1 184 ? 68.758  -26.017 -0.200  1.00 43.09  ?  6982 MET   B SD     1 
ATOM   2927 C  CE     . MET   A  1 184 ? 68.745  -24.236 -0.347  1.00 40.62  ?  6982 MET   B CE     1 
ATOM   2928 H  H      A MET   A  1 184 ? 65.217  -24.659 1.528   0.49 50.82  ?  6982 MET   B H      1 
ATOM   2929 H  H      B MET   A  1 184 ? 65.333  -24.584 1.486   0.51 50.82  ?  6982 MET   B H      1 
ATOM   2930 H  HA     . MET   A  1 184 ? 65.940  -25.567 -0.798  1.00 45.60  ?  6982 MET   B HA     1 
ATOM   2931 H  HB2    . MET   A  1 184 ? 65.829  -26.998 1.619   1.00 44.64  ?  6982 MET   B HB2    1 
ATOM   2932 H  HB3    . MET   A  1 184 ? 66.483  -27.576 0.290   1.00 44.64  ?  6982 MET   B HB3    1 
ATOM   2933 H  HG2    . MET   A  1 184 ? 67.472  -25.279 1.549   1.00 45.64  ?  6982 MET   B HG2    1 
ATOM   2934 H  HG3    . MET   A  1 184 ? 68.043  -26.729 1.860   1.00 45.64  ?  6982 MET   B HG3    1 
ATOM   2935 H  HE1    . MET   A  1 184 ? 69.289  -23.978 -1.108  1.00 49.26  ?  6982 MET   B HE1    1 
ATOM   2936 H  HE2    . MET   A  1 184 ? 67.831  -23.937 -0.477  1.00 49.26  ?  6982 MET   B HE2    1 
ATOM   2937 H  HE3    . MET   A  1 184 ? 69.108  -23.849 0.465   1.00 49.26  ?  6982 MET   B HE3    1 
ATOM   2938 N  N      . GLY   A  1 185 ? 63.083  -26.529 0.265   1.00 40.57  ?  6983 GLY   B N      1 
ATOM   2939 C  CA     . GLY   A  1 185 ? 61.824  -27.111 -0.135  1.00 42.95  ?  6983 GLY   B CA     1 
ATOM   2940 C  C      . GLY   A  1 185 ? 61.169  -26.440 -1.313  1.00 43.70  ?  6983 GLY   B C      1 
ATOM   2941 O  O      . GLY   A  1 185 ? 60.116  -26.904 -1.759  1.00 44.51  ?  6983 GLY   B O      1 
ATOM   2942 H  H      . GLY   A  1 185 ? 63.054  -26.125 1.023   1.00 49.21  ?  6983 GLY   B H      1 
ATOM   2943 H  HA2    . GLY   A  1 185 ? 61.971  -28.041 -0.367  1.00 52.07  ?  6983 GLY   B HA2    1 
ATOM   2944 H  HA3    . GLY   A  1 185 ? 61.208  -27.065 0.613   1.00 52.07  ?  6983 GLY   B HA3    1 
ATOM   2945 N  N      . HIS   A  1 186 ? 61.755  -25.350 -1.815  1.00 49.08  ?  6984 HIS   B N      1 
ATOM   2946 C  CA     . HIS   A  1 186 ? 61.290  -24.704 -3.033  1.00 42.41  ?  6984 HIS   B CA     1 
ATOM   2947 C  C      . HIS   A  1 186 ? 62.037  -25.188 -4.263  1.00 41.20  ?  6984 HIS   B C      1 
ATOM   2948 O  O      . HIS   A  1 186 ? 61.917  -24.576 -5.327  1.00 41.92  ?  6984 HIS   B O      1 
ATOM   2949 C  CB     . HIS   A  1 186 ? 61.415  -23.181 -2.940  1.00 46.94  ?  6984 HIS   B CB     1 
ATOM   2950 C  CG     . HIS   A  1 186 ? 60.564  -22.564 -1.876  1.00 45.98  ?  6984 HIS   B CG     1 
ATOM   2951 N  ND1    . HIS   A  1 186 ? 59.945  -21.343 -2.042  1.00 51.04  ?  6984 HIS   B ND1    1 
ATOM   2952 C  CD2    . HIS   A  1 186 ? 60.277  -22.965 -0.615  1.00 44.35  ?  6984 HIS   B CD2    1 
ATOM   2953 C  CE1    . HIS   A  1 186 ? 59.275  -21.040 -0.946  1.00 46.81  ?  6984 HIS   B CE1    1 
ATOM   2954 N  NE2    . HIS   A  1 186 ? 59.466  -22.004 -0.062  1.00 47.37  ?  6984 HIS   B NE2    1 
ATOM   2955 H  H      . HIS   A  1 186 ? 62.435  -24.964 -1.458  1.00 59.42  ?  6984 HIS   B H      1 
ATOM   2956 H  HA     . HIS   A  1 186 ? 60.348  -24.914 -3.132  1.00 51.42  ?  6984 HIS   B HA     1 
ATOM   2957 H  HB2    . HIS   A  1 186 ? 62.338  -22.956 -2.745  1.00 56.85  ?  6984 HIS   B HB2    1 
ATOM   2958 H  HB3    . HIS   A  1 186 ? 61.151  -22.795 -3.789  1.00 56.85  ?  6984 HIS   B HB3    1 
ATOM   2959 H  HD2    . HIS   A  1 186 ? 60.572  -23.744 -0.202  1.00 53.74  ?  6984 HIS   B HD2    1 
ATOM   2960 H  HE1    . HIS   A  1 186 ? 58.757  -20.278 -0.817  1.00 56.69  ?  6984 HIS   B HE1    1 
ATOM   2961 H  HE2    . HIS   A  1 186 ? 59.136  -22.026 0.732   1.00 57.36  ?  6984 HIS   B HE2    1 
ATOM   2962 N  N      . PHE   A  1 187 ? 62.815  -26.252 -4.141  1.00 44.99  ?  6985 PHE   B N      1 
ATOM   2963 C  CA     . PHE   A  1 187 ? 63.537  -26.852 -5.247  1.00 43.62  ?  6985 PHE   B CA     1 
ATOM   2964 C  C      . PHE   A  1 187 ? 62.987  -28.249 -5.484  1.00 44.80  ?  6985 PHE   B C      1 
ATOM   2965 O  O      . PHE   A  1 187 ? 62.312  -28.824 -4.624  1.00 46.07  ?  6985 PHE   B O      1 
ATOM   2966 C  CB     . PHE   A  1 187 ? 65.046  -26.925 -4.973  1.00 42.49  ?  6985 PHE   B CB     1 
ATOM   2967 C  CG     . PHE   A  1 187 ? 65.717  -25.580 -4.863  1.00 40.22  ?  6985 PHE   B CG     1 
ATOM   2968 C  CD1    . PHE   A  1 187 ? 65.556  -24.783 -3.753  1.00 38.97  ?  6985 PHE   B CD1    1 
ATOM   2969 C  CD2    . PHE   A  1 187 ? 66.550  -25.140 -5.870  1.00 42.41  ?  6985 PHE   B CD2    1 
ATOM   2970 C  CE1    . PHE   A  1 187 ? 66.186  -23.562 -3.675  1.00 40.83  ?  6985 PHE   B CE1    1 
ATOM   2971 C  CE2    . PHE   A  1 187 ? 67.189  -23.914 -5.786  1.00 40.31  ?  6985 PHE   B CE2    1 
ATOM   2972 C  CZ     . PHE   A  1 187 ? 67.000  -23.129 -4.696  1.00 40.71  ?  6985 PHE   B CZ     1 
ATOM   2973 H  H      . PHE   A  1 187 ? 62.944  -26.660 -3.395  1.00 54.51  ?  6985 PHE   B H      1 
ATOM   2974 H  HA     . PHE   A  1 187 ? 63.418  -26.314 -6.045  1.00 52.86  ?  6985 PHE   B HA     1 
ATOM   2975 H  HB2    . PHE   A  1 187 ? 65.187  -27.394 -4.135  1.00 51.51  ?  6985 PHE   B HB2    1 
ATOM   2976 H  HB3    . PHE   A  1 187 ? 65.471  -27.407 -5.699  1.00 51.51  ?  6985 PHE   B HB3    1 
ATOM   2977 H  HD1    . PHE   A  1 187 ? 65.018  -25.071 -3.051  1.00 47.29  ?  6985 PHE   B HD1    1 
ATOM   2978 H  HD2    . PHE   A  1 187 ? 66.685  -25.675 -6.619  1.00 51.41  ?  6985 PHE   B HD2    1 
ATOM   2979 H  HE1    . PHE   A  1 187 ? 66.060  -23.025 -2.926  1.00 49.52  ?  6985 PHE   B HE1    1 
ATOM   2980 H  HE2    . PHE   A  1 187 ? 67.746  -23.631 -6.474  1.00 48.89  ?  6985 PHE   B HE2    1 
ATOM   2981 H  HZ     . PHE   A  1 187 ? 67.420  -22.301 -4.639  1.00 49.38  ?  6985 PHE   B HZ     1 
ATOM   2982 N  N      . ALA   A  1 188 ? 63.285  -28.786 -6.667  1.00 42.11  ?  6986 ALA   B N      1 
ATOM   2983 C  CA     . ALA   A  1 188 ? 62.873  -30.144 -6.994  1.00 44.77  ?  6986 ALA   B CA     1 
ATOM   2984 C  C      . ALA   A  1 188 ? 63.603  -31.185 -6.152  1.00 44.12  ?  6986 ALA   B C      1 
ATOM   2985 O  O      . ALA   A  1 188 ? 63.100  -32.304 -5.999  1.00 46.97  ?  6986 ALA   B O      1 
ATOM   2986 C  CB     . ALA   A  1 188 ? 63.109  -30.411 -8.482  1.00 41.73  ?  6986 ALA   B CB     1 
ATOM   2987 H  H      . ALA   A  1 188 ? 63.721  -28.387 -7.291  1.00 51.06  ?  6986 ALA   B H      1 
ATOM   2988 H  HA     . ALA   A  1 188 ? 61.923  -30.238 -6.820  1.00 54.25  ?  6986 ALA   B HA     1 
ATOM   2989 H  HB1    . ALA   A  1 188 ? 62.815  -31.311 -8.692  1.00 50.60  ?  6986 ALA   B HB1    1 
ATOM   2990 H  HB2    . ALA   A  1 188 ? 62.602  -29.768 -9.003  1.00 50.60  ?  6986 ALA   B HB2    1 
ATOM   2991 H  HB3    . ALA   A  1 188 ? 64.055  -30.318 -8.674  1.00 50.60  ?  6986 ALA   B HB3    1 
ATOM   2992 N  N      . TRP   A  1 189 ? 64.764  -30.840 -5.605  1.00 45.62  ?  6987 TRP   B N      1 
ATOM   2993 C  CA     . TRP   A  1 189 ? 65.531  -31.736 -4.765  1.00 42.44  ?  6987 TRP   B CA     1 
ATOM   2994 C  C      . TRP   A  1 189 ? 66.535  -30.879 -4.010  1.00 43.48  ?  6987 TRP   B C      1 
ATOM   2995 O  O      . TRP   A  1 189 ? 66.821  -29.747 -4.395  1.00 41.03  ?  6987 TRP   B O      1 
ATOM   2996 C  CB     . TRP   A  1 189 ? 66.235  -32.813 -5.595  1.00 47.46  ?  6987 TRP   B CB     1 
ATOM   2997 C  CG     . TRP   A  1 189 ? 66.828  -33.923 -4.789  1.00 45.67  ?  6987 TRP   B CG     1 
ATOM   2998 C  CD1    . TRP   A  1 189 ? 66.166  -34.993 -4.252  1.00 50.89  ?  6987 TRP   B CD1    1 
ATOM   2999 C  CD2    . TRP   A  1 189 ? 68.205  -34.093 -4.454  1.00 45.11  ?  6987 TRP   B CD2    1 
ATOM   3000 N  NE1    . TRP   A  1 189 ? 67.051  -35.811 -3.593  1.00 49.95  ?  6987 TRP   B NE1    1 
ATOM   3001 C  CE2    . TRP   A  1 189 ? 68.311  -35.286 -3.707  1.00 44.38  ?  6987 TRP   B CE2    1 
ATOM   3002 C  CE3    . TRP   A  1 189 ? 69.359  -33.351 -4.710  1.00 40.14  ?  6987 TRP   B CE3    1 
ATOM   3003 C  CZ2    . TRP   A  1 189 ? 69.531  -35.755 -3.220  1.00 44.17  ?  6987 TRP   B CZ2    1 
ATOM   3004 C  CZ3    . TRP   A  1 189 ? 70.566  -33.811 -4.223  1.00 39.61  ?  6987 TRP   B CZ3    1 
ATOM   3005 C  CH2    . TRP   A  1 189 ? 70.643  -35.003 -3.482  1.00 41.42  ?  6987 TRP   B CH2    1 
ATOM   3006 H  H      . TRP   A  1 189 ? 65.134  -30.071 -5.711  1.00 55.27  ?  6987 TRP   B H      1 
ATOM   3007 H  HA     . TRP   A  1 189 ? 64.958  -32.190 -4.128  1.00 51.45  ?  6987 TRP   B HA     1 
ATOM   3008 H  HB2    . TRP   A  1 189 ? 65.589  -33.205 -6.204  1.00 57.48  ?  6987 TRP   B HB2    1 
ATOM   3009 H  HB3    . TRP   A  1 189 ? 66.954  -32.397 -6.096  1.00 57.48  ?  6987 TRP   B HB3    1 
ATOM   3010 H  HD1    . TRP   A  1 189 ? 65.251  -35.144 -4.323  1.00 61.59  ?  6987 TRP   B HD1    1 
ATOM   3011 H  HE1    . TRP   A  1 189 ? 66.847  -36.536 -3.176  1.00 60.46  ?  6987 TRP   B HE1    1 
ATOM   3012 H  HE3    . TRP   A  1 189 ? 69.316  -32.562 -5.200  1.00 48.69  ?  6987 TRP   B HE3    1 
ATOM   3013 H  HZ2    . TRP   A  1 189 ? 69.586  -36.547 -2.736  1.00 53.53  ?  6987 TRP   B HZ2    1 
ATOM   3014 H  HZ3    . TRP   A  1 189 ? 71.341  -33.325 -4.388  1.00 48.05  ?  6987 TRP   B HZ3    1 
ATOM   3015 H  HH2    . TRP   A  1 189 ? 71.469  -35.287 -3.163  1.00 50.22  ?  6987 TRP   B HH2    1 
ATOM   3016 N  N      . TRP   A  1 190 ? 67.055  -31.423 -2.919  1.00 44.07  ?  6988 TRP   B N      1 
ATOM   3017 C  CA     . TRP   A  1 190 ? 68.006  -30.688 -2.100  1.00 41.91  ?  6988 TRP   B CA     1 
ATOM   3018 C  C      . TRP   A  1 190 ? 68.806  -31.689 -1.280  1.00 37.28  ?  6988 TRP   B C      1 
ATOM   3019 O  O      . TRP   A  1 190 ? 68.392  -32.838 -1.093  1.00 40.90  ?  6988 TRP   B O      1 
ATOM   3020 C  CB     . TRP   A  1 190 ? 67.311  -29.670 -1.191  1.00 40.59  ?  6988 TRP   B CB     1 
ATOM   3021 C  CG     . TRP   A  1 190 ? 66.801  -30.298 0.064   1.00 43.54  ?  6988 TRP   B CG     1 
ATOM   3022 C  CD1    . TRP   A  1 190 ? 65.602  -30.931 0.217   1.00 39.24  ?  6988 TRP   B CD1    1 
ATOM   3023 C  CD2    . TRP   A  1 190 ? 67.475  -30.399 1.330   1.00 39.36  ?  6988 TRP   B CD2    1 
ATOM   3024 N  NE1    . TRP   A  1 190 ? 65.487  -31.419 1.492   1.00 44.49  ?  6988 TRP   B NE1    1 
ATOM   3025 C  CE2    . TRP   A  1 190 ? 66.620  -31.109 2.198   1.00 39.74  ?  6988 TRP   B CE2    1 
ATOM   3026 C  CE3    . TRP   A  1 190 ? 68.712  -29.962 1.809   1.00 41.02  ?  6988 TRP   B CE3    1 
ATOM   3027 C  CZ2    . TRP   A  1 190 ? 66.960  -31.374 3.525   1.00 38.71  ?  6988 TRP   B CZ2    1 
ATOM   3028 C  CZ3    . TRP   A  1 190 ? 69.057  -30.234 3.110   1.00 41.15  ?  6988 TRP   B CZ3    1 
ATOM   3029 C  CH2    . TRP   A  1 190 ? 68.185  -30.928 3.960   1.00 39.99  ?  6988 TRP   B CH2    1 
ATOM   3030 H  H      . TRP   A  1 190 ? 66.874  -32.214 -2.633  1.00 53.41  ?  6988 TRP   B H      1 
ATOM   3031 H  HA     . TRP   A  1 190 ? 68.616  -30.202 -2.676  1.00 50.82  ?  6988 TRP   B HA     1 
ATOM   3032 H  HB2    . TRP   A  1 190 ? 67.944  -28.976 -0.947  1.00 49.23  ?  6988 TRP   B HB2    1 
ATOM   3033 H  HB3    . TRP   A  1 190 ? 66.559  -29.281 -1.663  1.00 49.23  ?  6988 TRP   B HB3    1 
ATOM   3034 H  HD1    . TRP   A  1 190 ? 64.957  -31.018 -0.447  1.00 47.61  ?  6988 TRP   B HD1    1 
ATOM   3035 H  HE1    . TRP   A  1 190 ? 64.811  -31.852 1.801   1.00 53.90  ?  6988 TRP   B HE1    1 
ATOM   3036 H  HE3    . TRP   A  1 190 ? 69.294  -29.494 1.254   1.00 49.75  ?  6988 TRP   B HE3    1 
ATOM   3037 H  HZ2    . TRP   A  1 190 ? 66.382  -31.833 4.091   1.00 46.98  ?  6988 TRP   B HZ2    1 
ATOM   3038 H  HZ3    . TRP   A  1 190 ? 69.882  -29.952 3.433   1.00 49.91  ?  6988 TRP   B HZ3    1 
ATOM   3039 H  HH2    . TRP   A  1 190 ? 68.442  -31.091 4.839   1.00 48.51  ?  6988 TRP   B HH2    1 
ATOM   3040 N  N      . THR   A  1 191 ? 69.964  -31.239 -0.807  1.00 39.28  ?  6989 THR   B N      1 
ATOM   3041 C  CA     . THR   A  1 191 ? 70.724  -32.018 0.152   1.00 40.42  ?  6989 THR   B CA     1 
ATOM   3042 C  C      . THR   A  1 191 ? 71.734  -31.116 0.848   1.00 39.86  ?  6989 THR   B C      1 
ATOM   3043 O  O      . THR   A  1 191 ? 71.871  -29.935 0.530   1.00 41.19  ?  6989 THR   B O      1 
ATOM   3044 C  CB     . THR   A  1 191 ? 71.447  -33.188 -0.523  1.00 40.87  ?  6989 THR   B CB     1 
ATOM   3045 O  OG1    . THR   A  1 191 ? 71.959  -34.075 0.477   1.00 42.41  ?  6989 THR   B OG1    1 
ATOM   3046 C  CG2    . THR   A  1 191 ? 72.627  -32.670 -1.368  1.00 42.30  ?  6989 THR   B CG2    1 
ATOM   3047 H  H      . THR   A  1 191 ? 70.324  -30.490 -1.026  1.00 47.66  ?  6989 THR   B H      1 
ATOM   3048 H  HA     . THR   A  1 191 ? 70.109  -32.364 0.817   1.00 49.03  ?  6989 THR   B HA     1 
ATOM   3049 H  HB     . THR   A  1 191 ? 70.827  -33.662 -1.100  1.00 49.57  ?  6989 THR   B HB     1 
ATOM   3050 H  HG1    . THR   A  1 191 ? 71.930  -34.867 0.200   1.00 51.42  ?  6989 THR   B HG1    1 
ATOM   3051 H  HG21   . THR   A  1 191 ? 72.898  -33.346 -2.009  1.00 51.28  ?  6989 THR   B HG21   1 
ATOM   3052 H  HG22   . THR   A  1 191 ? 72.365  -31.869 -1.848  1.00 51.28  ?  6989 THR   B HG22   1 
ATOM   3053 H  HG23   . THR   A  1 191 ? 73.380  -32.461 -0.793  1.00 51.28  ?  6989 THR   B HG23   1 
ATOM   3054 N  N      . ALA   A  1 192 ? 72.400  -31.686 1.847   1.00 44.57  ?  6990 ALA   B N      1 
ATOM   3055 C  CA     . ALA   A  1 192 ? 73.587  -31.118 2.470   1.00 38.87  ?  6990 ALA   B CA     1 
ATOM   3056 C  C      . ALA   A  1 192 ? 74.753  -32.011 2.079   1.00 36.30  ?  6990 ALA   B C      1 
ATOM   3057 O  O      . ALA   A  1 192 ? 74.709  -33.222 2.316   1.00 42.16  ?  6990 ALA   B O      1 
ATOM   3058 C  CB     . ALA   A  1 192 ? 73.434  -31.047 3.984   1.00 36.07  ?  6990 ALA   B CB     1 
ATOM   3059 H  H      . ALA   A  1 192 ? 72.171  -32.438 2.196   1.00 54.01  ?  6990 ALA   B H      1 
ATOM   3060 H  HA     . ALA   A  1 192 ? 73.747  -30.214 2.154   1.00 47.17  ?  6990 ALA   B HA     1 
ATOM   3061 H  HB1    . ALA   A  1 192 ? 74.236  -30.657 4.365   1.00 43.80  ?  6990 ALA   B HB1    1 
ATOM   3062 H  HB2    . ALA   A  1 192 ? 72.665  -30.495 4.198   1.00 43.80  ?  6990 ALA   B HB2    1 
ATOM   3063 H  HB3    . ALA   A  1 192 ? 73.305  -31.943 4.331   1.00 43.80  ?  6990 ALA   B HB3    1 
ATOM   3064 N  N      . PHE   A  1 193 ? 75.780  -31.430 1.464   1.00 41.29  ?  6991 PHE   B N      1 
ATOM   3065 C  CA     . PHE   A  1 193 ? 76.898  -32.201 0.928   1.00 40.32  ?  6991 PHE   B CA     1 
ATOM   3066 C  C      . PHE   A  1 193 ? 78.193  -31.857 1.643   1.00 36.18  ?  6991 PHE   B C      1 
ATOM   3067 O  O      . PHE   A  1 193 ? 78.566  -30.681 1.736   1.00 40.38  ?  6991 PHE   B O      1 
ATOM   3068 C  CB     . PHE   A  1 193 ? 77.075  -31.975 -0.575  1.00 39.00  ?  6991 PHE   B CB     1 
ATOM   3069 C  CG     . PHE   A  1 193 ? 78.311  -32.645 -1.155  1.00 40.91  ?  6991 PHE   B CG     1 
ATOM   3070 C  CD1    . PHE   A  1 193 ? 78.331  -34.011 -1.381  1.00 38.47  ?  6991 PHE   B CD1    1 
ATOM   3071 C  CD2    . PHE   A  1 193 ? 79.456  -31.907 -1.452  1.00 38.92  ?  6991 PHE   B CD2    1 
ATOM   3072 C  CE1    . PHE   A  1 193 ? 79.453  -34.618 -1.906  1.00 41.48  ?  6991 PHE   B CE1    1 
ATOM   3073 C  CE2    . PHE   A  1 193 ? 80.578  -32.513 -1.960  1.00 40.11  ?  6991 PHE   B CE2    1 
ATOM   3074 C  CZ     . PHE   A  1 193 ? 80.572  -33.872 -2.194  1.00 39.28  ?  6991 PHE   B CZ     1 
ATOM   3075 H  H      . PHE   A  1 193 ? 75.851  -30.582 1.344   1.00 50.07  ?  6991 PHE   B H      1 
ATOM   3076 H  HA     . PHE   A  1 193 ? 76.708  -33.138 1.088   1.00 48.90  ?  6991 PHE   B HA     1 
ATOM   3077 H  HB2    . PHE   A  1 193 ? 76.301  -32.331 -1.038  1.00 47.33  ?  6991 PHE   B HB2    1 
ATOM   3078 H  HB3    . PHE   A  1 193 ? 77.151  -31.022 -0.741  1.00 47.33  ?  6991 PHE   B HB3    1 
ATOM   3079 H  HD1    . PHE   A  1 193 ? 77.582  -34.523 -1.177  1.00 46.69  ?  6991 PHE   B HD1    1 
ATOM   3080 H  HD2    . PHE   A  1 193 ? 79.459  -30.989 -1.303  1.00 47.22  ?  6991 PHE   B HD2    1 
ATOM   3081 H  HE1    . PHE   A  1 193 ? 79.453  -35.534 -2.066  1.00 50.30  ?  6991 PHE   B HE1    1 
ATOM   3082 H  HE2    . PHE   A  1 193 ? 81.339  -32.011 -2.145  1.00 48.65  ?  6991 PHE   B HE2    1 
ATOM   3083 H  HZ     . PHE   A  1 193 ? 81.326  -34.285 -2.547  1.00 47.66  ?  6991 PHE   B HZ     1 
ATOM   3084 N  N      . VAL   A  1 194 ? 78.897  -32.892 2.101   1.00 37.47  ?  6992 VAL   B N      1 
ATOM   3085 C  CA     . VAL   A  1 194 ? 80.145  -32.742 2.838   1.00 39.04  ?  6992 VAL   B CA     1 
ATOM   3086 C  C      . VAL   A  1 194 ? 81.268  -33.213 1.925   1.00 35.33  ?  6992 VAL   B C      1 
ATOM   3087 O  O      . VAL   A  1 194 ? 81.261  -34.360 1.460   1.00 42.56  ?  6992 VAL   B O      1 
ATOM   3088 C  CB     . VAL   A  1 194 ? 80.127  -33.546 4.146   1.00 40.37  ?  6992 VAL   B CB     1 
ATOM   3089 C  CG1    . VAL   A  1 194 ? 81.475  -33.450 4.839   1.00 44.81  ?  6992 VAL   B CG1    1 
ATOM   3090 C  CG2    . VAL   A  1 194 ? 78.976  -33.114 5.030   1.00 39.82  ?  6992 VAL   B CG2    1 
ATOM   3091 H  H      . VAL   A  1 194 ? 78.663  -33.712 1.992   1.00 45.49  ?  6992 VAL   B H      1 
ATOM   3092 H  HA     . VAL   A  1 194 ? 80.287  -31.808 3.057   1.00 47.37  ?  6992 VAL   B HA     1 
ATOM   3093 H  HB     . VAL   A  1 194 ? 79.977  -34.484 3.950   1.00 48.97  ?  6992 VAL   B HB     1 
ATOM   3094 H  HG11   . VAL   A  1 194 ? 81.379  -33.744 5.758   1.00 54.29  ?  6992 VAL   B HG11   1 
ATOM   3095 H  HG12   . VAL   A  1 194 ? 82.110  -34.018 4.375   1.00 54.29  ?  6992 VAL   B HG12   1 
ATOM   3096 H  HG13   . VAL   A  1 194 ? 81.777  -32.528 4.816   1.00 54.29  ?  6992 VAL   B HG13   1 
ATOM   3097 H  HG21   . VAL   A  1 194 ? 79.027  -33.593 5.872   1.00 48.30  ?  6992 VAL   B HG21   1 
ATOM   3098 H  HG22   . VAL   A  1 194 ? 79.040  -32.159 5.188   1.00 48.30  ?  6992 VAL   B HG22   1 
ATOM   3099 H  HG23   . VAL   A  1 194 ? 78.140  -33.319 4.583   1.00 48.30  ?  6992 VAL   B HG23   1 
ATOM   3100 N  N      . THR   A  1 195 ? 82.250  -32.351 1.675   1.00 41.43  ?  6993 THR   B N      1 
ATOM   3101 C  CA     . THR   A  1 195 ? 83.377  -32.788 0.861   1.00 40.77  ?  6993 THR   B CA     1 
ATOM   3102 C  C      . THR   A  1 195 ? 84.249  -33.733 1.670   1.00 35.48  ?  6993 THR   B C      1 
ATOM   3103 O  O      . THR   A  1 195 ? 84.450  -33.549 2.875   1.00 37.31  ?  6993 THR   B O      1 
ATOM   3104 C  CB     . THR   A  1 195 ? 84.226  -31.611 0.357   1.00 38.53  ?  6993 THR   B CB     1 
ATOM   3105 O  OG1    . THR   A  1 195 ? 84.873  -30.948 1.447   1.00 40.12  ?  6993 THR   B OG1    1 
ATOM   3106 C  CG2    . THR   A  1 195 ? 83.367  -30.640 -0.413  1.00 38.47  ?  6993 THR   B CG2    1 
ATOM   3107 H  H      . THR   A  1 195 ? 82.285  -31.538 1.955   1.00 50.24  ?  6993 THR   B H      1 
ATOM   3108 H  HA     . THR   A  1 195 ? 83.033  -33.241 0.075   1.00 49.44  ?  6993 THR   B HA     1 
ATOM   3109 H  HB     . THR   A  1 195 ? 84.915  -31.947 -0.238  1.00 46.76  ?  6993 THR   B HB     1 
ATOM   3110 H  HG1    . THR   A  1 195 ? 84.300  -30.602 1.954   1.00 48.67  ?  6993 THR   B HG1    1 
ATOM   3111 H  HG21   . THR   A  1 195 ? 83.907  -29.898 -0.728  1.00 46.68  ?  6993 THR   B HG21   1 
ATOM   3112 H  HG22   . THR   A  1 195 ? 82.966  -31.084 -1.176  1.00 46.68  ?  6993 THR   B HG22   1 
ATOM   3113 H  HG23   . THR   A  1 195 ? 82.663  -30.296 0.158   1.00 46.68  ?  6993 THR   B HG23   1 
ATOM   3114 N  N      . ASN   A  1 196 ? 84.767  -34.764 1.004   1.00 37.90  ?  6994 ASN   B N      1 
ATOM   3115 C  CA     . ASN   A  1 196 ? 85.635  -35.726 1.688   1.00 40.29  ?  6994 ASN   B CA     1 
ATOM   3116 C  C      . ASN   A  1 196 ? 86.933  -35.089 2.152   1.00 37.96  ?  6994 ASN   B C      1 
ATOM   3117 O  O      . ASN   A  1 196 ? 87.528  -35.550 3.137   1.00 40.37  ?  6994 ASN   B O      1 
ATOM   3118 C  CB     . ASN   A  1 196 ? 85.926  -36.910 0.769   1.00 41.54  ?  6994 ASN   B CB     1 
ATOM   3119 C  CG     . ASN   A  1 196 ? 84.905  -38.017 0.907   1.00 40.07  ?  6994 ASN   B CG     1 
ATOM   3120 O  OD1    . ASN   A  1 196 ? 84.207  -38.110 1.921   1.00 42.48  ?  6994 ASN   B OD1    1 
ATOM   3121 N  ND2    . ASN   A  1 196 ? 84.807  -38.869 -0.112  1.00 42.51  ?  6994 ASN   B ND2    1 
ATOM   3122 H  H      . ASN   A  1 196 ? 84.635  -34.929 0.170   1.00 46.00  ?  6994 ASN   B H      1 
ATOM   3123 H  HA     . ASN   A  1 196 ? 85.170  -36.057 2.472   1.00 48.87  ?  6994 ASN   B HA     1 
ATOM   3124 H  HB2    . ASN   A  1 196 ? 85.918  -36.606 -0.152  1.00 50.37  ?  6994 ASN   B HB2    1 
ATOM   3125 H  HB3    . ASN   A  1 196 ? 86.797  -37.275 0.990   1.00 50.37  ?  6994 ASN   B HB3    1 
ATOM   3126 H  HD21   . ASN   A  1 196 ? 84.241  -39.515 -0.080  1.00 51.53  ?  6994 ASN   B HD21   1 
ATOM   3127 H  HD22   . ASN   A  1 196 ? 85.311  -38.772 -0.803  1.00 51.53  ?  6994 ASN   B HD22   1 
ATOM   3128 N  N      . VAL   A  1 197 ? 87.409  -34.049 1.457   1.00 38.48  ?  6995 VAL   B N      1 
ATOM   3129 C  CA     . VAL   A  1 197 ? 88.644  -33.430 1.937   1.00 38.10  ?  6995 VAL   B CA     1 
ATOM   3130 C  C      . VAL   A  1 197 ? 88.425  -32.687 3.252   1.00 41.43  ?  6995 VAL   B C      1 
ATOM   3131 O  O      . VAL   A  1 197 ? 89.389  -32.447 3.988   1.00 42.77  ?  6995 VAL   B O      1 
ATOM   3132 C  CB     . VAL   A  1 197 ? 89.313  -32.442 0.959   1.00 39.52  ?  6995 VAL   B CB     1 
ATOM   3133 C  CG1    . VAL   A  1 197 ? 89.987  -33.180 -0.173  1.00 51.68  ?  6995 VAL   B CG1    1 
ATOM   3134 C  CG2    . VAL   A  1 197 ? 88.317  -31.420 0.426   1.00 36.76  ?  6995 VAL   B CG2    1 
ATOM   3135 H  H      . VAL   A  1 197 ? 87.058  -33.708 0.750   1.00 46.70  ?  6995 VAL   B H      1 
ATOM   3136 H  HA     . VAL   A  1 197 ? 89.250  -34.181 2.039   1.00 46.24  ?  6995 VAL   B HA     1 
ATOM   3137 H  HB     . VAL   A  1 197 ? 89.993  -31.954 1.448   1.00 47.94  ?  6995 VAL   B HB     1 
ATOM   3138 H  HG11   . VAL   A  1 197 ? 90.455  -32.540 -0.733  1.00 62.54  ?  6995 VAL   B HG11   1 
ATOM   3139 H  HG12   . VAL   A  1 197 ? 90.617  -33.818 0.196   1.00 62.54  ?  6995 VAL   B HG12   1 
ATOM   3140 H  HG13   . VAL   A  1 197 ? 89.313  -33.644 -0.694  1.00 62.54  ?  6995 VAL   B HG13   1 
ATOM   3141 H  HG21   . VAL   A  1 197 ? 88.780  -30.810 -0.170  1.00 44.63  ?  6995 VAL   B HG21   1 
ATOM   3142 H  HG22   . VAL   A  1 197 ? 87.615  -31.885 -0.056  1.00 44.63  ?  6995 VAL   B HG22   1 
ATOM   3143 H  HG23   . VAL   A  1 197 ? 87.938  -30.930 1.172   1.00 44.63  ?  6995 VAL   B HG23   1 
ATOM   3144 N  N      . ASN   A  1 198 ? 87.195  -32.273 3.561   1.00 40.50  ?  6996 ASN   B N      1 
ATOM   3145 C  CA     . ASN   A  1 198 ? 86.915  -31.494 4.765   1.00 41.86  ?  6996 ASN   B CA     1 
ATOM   3146 C  C      . ASN   A  1 198 ? 85.945  -32.212 5.699   1.00 37.26  ?  6996 ASN   B C      1 
ATOM   3147 O  O      . ASN   A  1 198 ? 85.222  -31.576 6.471   1.00 40.57  ?  6996 ASN   B O      1 
ATOM   3148 C  CB     . ASN   A  1 198 ? 86.383  -30.109 4.409   1.00 38.35  ?  6996 ASN   B CB     1 
ATOM   3149 C  CG     . ASN   A  1 198 ? 86.709  -29.071 5.456   1.00 40.64  ?  6996 ASN   B CG     1 
ATOM   3150 O  OD1    . ASN   A  1 198 ? 87.633  -29.247 6.245   1.00 45.60  ?  6996 ASN   B OD1    1 
ATOM   3151 N  ND2    . ASN   A  1 198 ? 85.944  -27.984 5.477   1.00 39.10  ?  6996 ASN   B ND2    1 
ATOM   3152 H  H      . ASN   A  1 198 ? 86.500  -32.433 3.082   1.00 49.12  ?  6996 ASN   B H      1 
ATOM   3153 H  HA     . ASN   A  1 198 ? 87.750  -31.380 5.245   1.00 50.75  ?  6996 ASN   B HA     1 
ATOM   3154 H  HB2    . ASN   A  1 198 ? 86.779  -29.825 3.570   1.00 46.54  ?  6996 ASN   B HB2    1 
ATOM   3155 H  HB3    . ASN   A  1 198 ? 85.418  -30.154 4.321   1.00 46.54  ?  6996 ASN   B HB3    1 
ATOM   3156 H  HD21   . ASN   A  1 198 ? 86.092  -27.365 6.056   1.00 47.44  ?  6996 ASN   B HD21   1 
ATOM   3157 H  HD22   . ASN   A  1 198 ? 85.301  -27.899 4.912   1.00 47.44  ?  6996 ASN   B HD22   1 
ATOM   3158 N  N      . ALA   A  1 199 ? 85.934  -33.546 5.643   1.00 39.92  ?  6997 ALA   B N      1 
ATOM   3159 C  CA     . ALA   A  1 199 ? 84.970  -34.338 6.399   1.00 40.15  ?  6997 ALA   B CA     1 
ATOM   3160 C  C      . ALA   A  1 199 ? 85.119  -34.161 7.903   1.00 42.02  ?  6997 ALA   B C      1 
ATOM   3161 O  O      . ALA   A  1 199 ? 84.204  -34.518 8.650   1.00 43.99  ?  6997 ALA   B O      1 
ATOM   3162 C  CB     . ALA   A  1 199 ? 85.133  -35.812 6.024   1.00 44.42  ?  6997 ALA   B CB     1 
ATOM   3163 H  H      . ALA   A  1 199 ? 86.479  -34.017 5.173   1.00 48.42  ?  6997 ALA   B H      1 
ATOM   3164 H  HA     . ALA   A  1 199 ? 84.073  -34.055 6.164   1.00 48.70  ?  6997 ALA   B HA     1 
ATOM   3165 H  HB1    . ALA   A  1 199 ? 84.562  -36.348 6.596   1.00 53.83  ?  6997 ALA   B HB1    1 
ATOM   3166 H  HB2    . ALA   A  1 199 ? 84.879  -35.932 5.096   1.00 53.83  ?  6997 ALA   B HB2    1 
ATOM   3167 H  HB3    . ALA   A  1 199 ? 86.060  -36.069 6.149   1.00 53.83  ?  6997 ALA   B HB3    1 
ATOM   3168 N  N      . SER   A  1 200 ? 86.255  -33.640 8.356   1.00 43.99  ?  6998 SER   B N      1 
ATOM   3169 C  CA     . SER   A  1 200 ? 86.515  -33.377 9.760   1.00 43.93  ?  6998 SER   B CA     1 
ATOM   3170 C  C      . SER   A  1 200 ? 85.894  -32.084 10.257  1.00 40.91  ?  6998 SER   B C      1 
ATOM   3171 O  O      . SER   A  1 200 ? 86.098  -31.730 11.422  1.00 49.59  ?  6998 SER   B O      1 
ATOM   3172 C  CB     . SER   A  1 200 ? 88.022  -33.323 9.994   1.00 48.08  ?  6998 SER   B CB     1 
ATOM   3173 O  OG     . SER   A  1 200 ? 88.611  -32.412 9.082   1.00 50.51  ?  6998 SER   B OG     1 
ATOM   3174 H  H      . SER   A  1 200 ? 86.914  -33.423 7.848   1.00 53.31  ?  6998 SER   B H      1 
ATOM   3175 H  HA     . SER   A  1 200 ? 86.139  -34.104 10.281  1.00 53.24  ?  6998 SER   B HA     1 
ATOM   3176 H  HB2    . SER   A  1 200 ? 88.196  -33.027 10.901  1.00 58.22  ?  6998 SER   B HB2    1 
ATOM   3177 H  HB3    . SER   A  1 200 ? 88.401  -34.206 9.856   1.00 58.22  ?  6998 SER   B HB3    1 
ATOM   3178 H  HG     . SER   A  1 200 ? 89.438  -32.362 9.218   1.00 61.14  ?  6998 SER   B HG     1 
ATOM   3179 N  N      . SER   A  1 201 ? 85.151  -31.389 9.411   1.00 42.20  ?  6999 SER   B N      1 
ATOM   3180 C  CA     . SER   A  1 201 ? 84.568  -30.106 9.725   1.00 37.44  ?  6999 SER   B CA     1 
ATOM   3181 C  C      . SER   A  1 201 ? 83.056  -30.249 9.635   1.00 39.55  ?  6999 SER   B C      1 
ATOM   3182 O  O      . SER   A  1 201 ? 82.538  -31.093 8.889   1.00 45.96  ?  6999 SER   B O      1 
ATOM   3183 C  CB     . SER   A  1 201 ? 85.107  -29.033 8.774   1.00 38.14  ?  6999 SER   B CB     1 
ATOM   3184 O  OG     . SER   A  1 201 ? 84.213  -27.957 8.667   1.00 41.34  ?  6999 SER   B OG     1 
ATOM   3185 H  H      . SER   A  1 201 ? 84.964  -31.656 8.616   1.00 51.16  ?  6999 SER   B H      1 
ATOM   3186 H  HA     . SER   A  1 201 ? 84.783  -29.811 10.624  1.00 45.45  ?  6999 SER   B HA     1 
ATOM   3187 H  HB2    . SER   A  1 201 ? 85.954  -28.706 9.116   1.00 46.29  ?  6999 SER   B HB2    1 
ATOM   3188 H  HB3    . SER   A  1 201 ? 85.234  -29.426 7.896   1.00 46.29  ?  6999 SER   B HB3    1 
ATOM   3189 H  HG     . SER   A  1 201 ? 84.578  -27.251 8.941   1.00 50.13  ?  6999 SER   B HG     1 
ATOM   3190 N  N      . SER   A  1 202 ? 82.353  -29.507 10.486  1.00 44.30  ?  7000 SER   B N      1 
ATOM   3191 C  CA     . SER   A  1 202 ? 80.899  -29.496 10.413  1.00 39.85  ?  7000 SER   B CA     1 
ATOM   3192 C  C      . SER   A  1 202 ? 80.388  -28.761 9.182   1.00 40.94  ?  7000 SER   B C      1 
ATOM   3193 O  O      . SER   A  1 202 ? 79.175  -28.718 8.944   1.00 40.42  ?  7000 SER   B O      1 
ATOM   3194 C  CB     . SER   A  1 202 ? 80.314  -28.859 11.671  1.00 36.94  ?  7000 SER   B CB     1 
ATOM   3195 O  OG     . SER   A  1 202 ? 80.596  -27.470 11.689  1.00 39.85  ?  7000 SER   B OG     1 
ATOM   3196 H  H      . SER   A  1 202 ? 82.690  -29.012 11.103  1.00 53.68  ?  7000 SER   B H      1 
ATOM   3197 H  HA     . SER   A  1 202 ? 80.583  -30.412 10.373  1.00 48.35  ?  7000 SER   B HA     1 
ATOM   3198 H  HB2    . SER   A  1 202 ? 79.353  -28.989 11.676  1.00 44.85  ?  7000 SER   B HB2    1 
ATOM   3199 H  HB3    . SER   A  1 202 ? 80.709  -29.275 12.453  1.00 44.85  ?  7000 SER   B HB3    1 
ATOM   3200 H  HG     . SER   A  1 202 ? 80.381  -27.143 12.433  1.00 48.34  ?  7000 SER   B HG     1 
ATOM   3201 N  N      . GLU   A  1 203 ? 81.288  -28.185 8.396   1.00 44.38  ?  7001 GLU   B N      1 
ATOM   3202 C  CA     . GLU   A  1 203 ? 80.917  -27.574 7.130   1.00 40.59  ?  7001 GLU   B CA     1 
ATOM   3203 C  C      . GLU   A  1 203 ? 80.142  -28.550 6.258   1.00 36.03  ?  7001 GLU   B C      1 
ATOM   3204 O  O      . GLU   A  1 203 ? 80.432  -29.747 6.231   1.00 41.92  ?  7001 GLU   B O      1 
ATOM   3205 C  CB     . GLU   A  1 203 ? 82.181  -27.114 6.407   1.00 41.88  ?  7001 GLU   B CB     1 
ATOM   3206 C  CG     . GLU   A  1 203 ? 81.955  -26.516 5.011   1.00 41.05  ?  7001 GLU   B CG     1 
ATOM   3207 C  CD     . GLU   A  1 203 ? 83.244  -26.394 4.226   1.00 36.26  ?  7001 GLU   B CD     1 
ATOM   3208 O  OE1    . GLU   A  1 203 ? 83.697  -27.385 3.626   1.00 39.88  ?  7001 GLU   B OE1    1 
ATOM   3209 O  OE2    . GLU   A  1 203 ? 83.829  -25.297 4.218   1.00 41.18  ?  7001 GLU   B OE2    1 
ATOM   3210 H  H      . GLU   A  1 203 ? 82.128  -28.135 8.575   1.00 53.78  ?  7001 GLU   B H      1 
ATOM   3211 H  HA     . GLU   A  1 203 ? 80.346  -26.807 7.292   1.00 49.23  ?  7001 GLU   B HA     1 
ATOM   3212 H  HB2    . GLU   A  1 203 ? 82.612  -26.433 6.947   1.00 50.78  ?  7001 GLU   B HB2    1 
ATOM   3213 H  HB3    . GLU   A  1 203 ? 82.770  -27.878 6.304   1.00 50.78  ?  7001 GLU   B HB3    1 
ATOM   3214 H  HG2    . GLU   A  1 203 ? 81.351  -27.090 4.513   1.00 49.78  ?  7001 GLU   B HG2    1 
ATOM   3215 H  HG3    . GLU   A  1 203 ? 81.571  -25.630 5.102   1.00 49.78  ?  7001 GLU   B HG3    1 
ATOM   3216 N  N      . ALA   A  1 204 ? 79.145  -28.016 5.558   1.00 38.94  ?  7002 ALA   B N      1 
ATOM   3217 C  CA     . ALA   A  1 204 ? 78.524  -28.670 4.417   1.00 39.53  ?  7002 ALA   B CA     1 
ATOM   3218 C  C      . ALA   A  1 204 ? 78.021  -27.589 3.469   1.00 38.13  ?  7002 ALA   B C      1 
ATOM   3219 O  O      . ALA   A  1 204 ? 77.985  -26.403 3.811   1.00 38.49  ?  7002 ALA   B O      1 
ATOM   3220 C  CB     . ALA   A  1 204 ? 77.378  -29.585 4.842   1.00 43.10  ?  7002 ALA   B CB     1 
ATOM   3221 H  H      . ALA   A  1 204 ? 78.800  -27.247 5.731   1.00 47.25  ?  7002 ALA   B H      1 
ATOM   3222 H  HA     . ALA   A  1 204 ? 79.185  -29.213 3.959   1.00 47.96  ?  7002 ALA   B HA     1 
ATOM   3223 H  HB1    . ALA   A  1 204 ? 76.976  -29.977 4.051   1.00 52.24  ?  7002 ALA   B HB1    1 
ATOM   3224 H  HB2    . ALA   A  1 204 ? 77.728  -30.284 5.417   1.00 52.24  ?  7002 ALA   B HB2    1 
ATOM   3225 H  HB3    . ALA   A  1 204 ? 76.718  -29.061 5.323   1.00 52.24  ?  7002 ALA   B HB3    1 
ATOM   3226 N  N      . PHE   A  1 205 ? 77.646  -28.008 2.264   1.00 40.27  ?  7003 PHE   B N      1 
ATOM   3227 C  CA     . PHE   A  1 205 ? 77.039  -27.134 1.271   1.00 39.32  ?  7003 PHE   B CA     1 
ATOM   3228 C  C      . PHE   A  1 205 ? 75.572  -27.509 1.128   1.00 36.49  ?  7003 PHE   B C      1 
ATOM   3229 O  O      . PHE   A  1 205 ? 75.249  -28.650 0.777   1.00 39.07  ?  7003 PHE   B O      1 
ATOM   3230 C  CB     . PHE   A  1 205 ? 77.766  -27.214 -0.070  1.00 39.05  ?  7003 PHE   B CB     1 
ATOM   3231 C  CG     . PHE   A  1 205 ? 79.130  -26.610 -0.044  1.00 40.39  ?  7003 PHE   B CG     1 
ATOM   3232 C  CD1    . PHE   A  1 205 ? 80.234  -27.370 0.280   1.00 39.46  ?  7003 PHE   B CD1    1 
ATOM   3233 C  CD2    . PHE   A  1 205 ? 79.307  -25.267 -0.335  1.00 40.12  ?  7003 PHE   B CD2    1 
ATOM   3234 C  CE1    . PHE   A  1 205 ? 81.500  -26.801 0.328   1.00 39.12  ?  7003 PHE   B CE1    1 
ATOM   3235 C  CE2    . PHE   A  1 205 ? 80.571  -24.689 -0.298  1.00 38.21  ?  7003 PHE   B CE2    1 
ATOM   3236 C  CZ     . PHE   A  1 205 ? 81.670  -25.461 0.031   1.00 40.74  ?  7003 PHE   B CZ     1 
ATOM   3237 H  H      . PHE   A  1 205 ? 77.736  -28.820 1.993   1.00 48.84  ?  7003 PHE   B H      1 
ATOM   3238 H  HA     . PHE   A  1 205 ? 77.092  -26.214 1.574   1.00 47.70  ?  7003 PHE   B HA     1 
ATOM   3239 H  HB2    . PHE   A  1 205 ? 77.859  -28.146 -0.321  1.00 47.39  ?  7003 PHE   B HB2    1 
ATOM   3240 H  HB3    . PHE   A  1 205 ? 77.245  -26.741 -0.738  1.00 47.39  ?  7003 PHE   B HB3    1 
ATOM   3241 H  HD1    . PHE   A  1 205 ? 80.130  -28.275 0.469   1.00 47.87  ?  7003 PHE   B HD1    1 
ATOM   3242 H  HD2    . PHE   A  1 205 ? 78.570  -24.745 -0.558  1.00 48.66  ?  7003 PHE   B HD2    1 
ATOM   3243 H  HE1    . PHE   A  1 205 ? 82.235  -27.322 0.561   1.00 47.46  ?  7003 PHE   B HE1    1 
ATOM   3244 H  HE2    . PHE   A  1 205 ? 80.677  -23.786 -0.493  1.00 46.38  ?  7003 PHE   B HE2    1 
ATOM   3245 H  HZ     . PHE   A  1 205 ? 82.519  -25.081 0.051   1.00 49.42  ?  7003 PHE   B HZ     1 
ATOM   3246 N  N      . LEU   A  1 206 ? 74.685  -26.563 1.444   1.00 37.93  ?  7004 LEU   B N      1 
ATOM   3247 C  CA     . LEU   A  1 206 ? 73.263  -26.751 1.194   1.00 37.80  ?  7004 LEU   B CA     1 
ATOM   3248 C  C      . LEU   A  1 206 ? 72.992  -26.565 -0.292  1.00 36.94  ?  7004 LEU   B C      1 
ATOM   3249 O  O      . LEU   A  1 206 ? 73.163  -25.466 -0.827  1.00 41.68  ?  7004 LEU   B O      1 
ATOM   3250 C  CB     . LEU   A  1 206 ? 72.408  -25.788 2.016   1.00 42.99  ?  7004 LEU   B CB     1 
ATOM   3251 C  CG     . LEU   A  1 206 ? 72.096  -26.164 3.465   1.00 42.49  ?  7004 LEU   B CG     1 
ATOM   3252 C  CD1    . LEU   A  1 206 ? 71.051  -25.187 3.978   1.00 47.21  ?  7004 LEU   B CD1    1 
ATOM   3253 C  CD2    . LEU   A  1 206 ? 71.622  -27.587 3.580   1.00 44.40  ?  7004 LEU   B CD2    1 
ATOM   3254 H  H      . LEU   A  1 206 ? 74.886  -25.807 1.802   1.00 46.04  ?  7004 LEU   B H      1 
ATOM   3255 H  HA     . LEU   A  1 206 ? 73.017  -27.651 1.461   1.00 45.89  ?  7004 LEU   B HA     1 
ATOM   3256 H  HB2    . LEU   A  1 206 ? 72.867  -24.935 2.042   1.00 52.10  ?  7004 LEU   B HB2    1 
ATOM   3257 H  HB3    . LEU   A  1 206 ? 71.555  -25.692 1.564   1.00 52.10  ?  7004 LEU   B HB3    1 
ATOM   3258 H  HG     . LEU   A  1 206 ? 72.896  -26.108 4.011   1.00 51.51  ?  7004 LEU   B HG     1 
ATOM   3259 H  HD11   . LEU   A  1 206 ? 70.838  -25.407 4.899   1.00 57.18  ?  7004 LEU   B HD11   1 
ATOM   3260 H  HD12   . LEU   A  1 206 ? 71.409  -24.287 3.928   1.00 57.18  ?  7004 LEU   B HD12   1 
ATOM   3261 H  HD13   . LEU   A  1 206 ? 70.255  -25.258 3.428   1.00 57.18  ?  7004 LEU   B HD13   1 
ATOM   3262 H  HD21   . LEU   A  1 206 ? 71.245  -27.724 4.463   1.00 53.80  ?  7004 LEU   B HD21   1 
ATOM   3263 H  HD22   . LEU   A  1 206 ? 70.946  -27.750 2.903   1.00 53.80  ?  7004 LEU   B HD22   1 
ATOM   3264 H  HD23   . LEU   A  1 206 ? 72.375  -28.183 3.445   1.00 53.80  ?  7004 LEU   B HD23   1 
ATOM   3265 N  N      . ILE   A  1 207 ? 72.564  -27.635 -0.957  1.00 43.05  ?  7005 ILE   B N      1 
ATOM   3266 C  CA     . ILE   A  1 207 ? 72.369  -27.639 -2.398  1.00 38.11  ?  7005 ILE   B CA     1 
ATOM   3267 C  C      . ILE   A  1 207 ? 70.878  -27.725 -2.686  1.00 35.25  ?  7005 ILE   B C      1 
ATOM   3268 O  O      . ILE   A  1 207 ? 70.193  -28.632 -2.205  1.00 39.40  ?  7005 ILE   B O      1 
ATOM   3269 C  CB     . ILE   A  1 207 ? 73.118  -28.796 -3.064  1.00 37.50  ?  7005 ILE   B CB     1 
ATOM   3270 C  CG1    . ILE   A  1 207 ? 74.623  -28.562 -2.956  1.00 38.53  ?  7005 ILE   B CG1    1 
ATOM   3271 C  CG2    . ILE   A  1 207 ? 72.696  -28.926 -4.537  1.00 37.01  ?  7005 ILE   B CG2    1 
ATOM   3272 C  CD1    . ILE   A  1 207 ? 75.423  -29.851 -3.059  1.00 35.22  ?  7005 ILE   B CD1    1 
ATOM   3273 H  H      . ILE   A  1 207 ? 72.376  -28.387 -0.582  1.00 52.18  ?  7005 ILE   B H      1 
ATOM   3274 H  HA     . ILE   A  1 207 ? 72.704  -26.805 -2.763  1.00 46.25  ?  7005 ILE   B HA     1 
ATOM   3275 H  HB     . ILE   A  1 207 ? 72.893  -29.622 -2.609  1.00 45.53  ?  7005 ILE   B HB     1 
ATOM   3276 H  HG12   . ILE   A  1 207 ? 74.904  -27.975 -3.674  1.00 46.75  ?  7005 ILE   B HG12   1 
ATOM   3277 H  HG13   . ILE   A  1 207 ? 74.819  -28.155 -2.098  1.00 46.75  ?  7005 ILE   B HG13   1 
ATOM   3278 H  HG21   . ILE   A  1 207 ? 73.374  -29.427 -5.017  1.00 44.94  ?  7005 ILE   B HG21   1 
ATOM   3279 H  HG22   . ILE   A  1 207 ? 71.847  -29.391 -4.583  1.00 44.94  ?  7005 ILE   B HG22   1 
ATOM   3280 H  HG23   . ILE   A  1 207 ? 72.608  -28.039 -4.920  1.00 44.94  ?  7005 ILE   B HG23   1 
ATOM   3281 H  HD11   . ILE   A  1 207 ? 76.365  -29.647 -2.949  1.00 42.79  ?  7005 ILE   B HD11   1 
ATOM   3282 H  HD12   . ILE   A  1 207 ? 75.132  -30.460 -2.363  1.00 42.79  ?  7005 ILE   B HD12   1 
ATOM   3283 H  HD13   . ILE   A  1 207 ? 75.271  -30.248 -3.931  1.00 42.79  ?  7005 ILE   B HD13   1 
ATOM   3284 N  N      . GLY   A  1 208 ? 70.373  -26.758 -3.443  1.00 44.52  ?  7006 GLY   B N      1 
ATOM   3285 C  CA     . GLY   A  1 208 ? 69.031  -26.825 -3.975  1.00 40.99  ?  7006 GLY   B CA     1 
ATOM   3286 C  C      . GLY   A  1 208 ? 69.132  -27.041 -5.466  1.00 37.11  ?  7006 GLY   B C      1 
ATOM   3287 O  O      . GLY   A  1 208 ? 69.789  -26.266 -6.171  1.00 43.68  ?  7006 GLY   B O      1 
ATOM   3288 H  H      . GLY   A  1 208 ? 70.799  -26.044 -3.664  1.00 53.94  ?  7006 GLY   B H      1 
ATOM   3289 H  HA2    . GLY   A  1 208 ? 68.545  -27.561 -3.573  1.00 49.71  ?  7006 GLY   B HA2    1 
ATOM   3290 H  HA3    . GLY   A  1 208 ? 68.556  -25.998 -3.798  1.00 49.71  ?  7006 GLY   B HA3    1 
ATOM   3291 N  N      . CYS   A  1 209 ? 68.492  -28.093 -5.966  1.00 41.90  ?  7007 CYS   B N      1 
ATOM   3292 C  CA     . CYS   A  1 209 ? 68.643  -28.533 -7.347  1.00 43.51  ?  7007 CYS   B CA     1 
ATOM   3293 C  C      . CYS   A  1 209 ? 67.347  -28.257 -8.102  1.00 42.55  ?  7007 CYS   B C      1 
ATOM   3294 O  O      . CYS   A  1 209 ? 66.316  -28.890 -7.836  1.00 43.74  ?  7007 CYS   B O      1 
ATOM   3295 C  CB     . CYS   A  1 209 ? 69.007  -30.009 -7.413  1.00 38.83  ?  7007 CYS   B CB     1 
ATOM   3296 S  SG     . CYS   A  1 209 ? 69.582  -30.569 -9.009  1.00 45.41  ?  7007 CYS   B SG     1 
ATOM   3297 H  H      . CYS   A  1 209 ? 67.949  -28.581 -5.511  1.00 50.80  ?  7007 CYS   B H      1 
ATOM   3298 H  HA     . CYS   A  1 209 ? 69.351  -28.018 -7.765  1.00 52.74  ?  7007 CYS   B HA     1 
ATOM   3299 H  HB2    . CYS   A  1 209 ? 69.715  -30.179 -6.771  1.00 47.12  ?  7007 CYS   B HB2    1 
ATOM   3300 H  HB3    . CYS   A  1 209 ? 68.221  -30.530 -7.186  1.00 47.12  ?  7007 CYS   B HB3    1 
ATOM   3301 H  HG     . CYS   A  1 209 ? 68.878  -30.106 -9.863  1.00 55.01  ?  7007 CYS   B HG     1 
ATOM   3302 N  N      . ASN   A  1 210 ? 67.414  -27.310 -9.038  1.00 40.56  ?  7008 ASN   B N      1 
ATOM   3303 C  CA     . ASN   A  1 210 ? 66.299  -26.913 -9.897  1.00 41.83  ?  7008 ASN   B CA     1 
ATOM   3304 C  C      . ASN   A  1 210 ? 65.205  -26.169 -9.139  1.00 42.23  ?  7008 ASN   B C      1 
ATOM   3305 O  O      . ASN   A  1 210 ? 64.295  -26.783 -8.575  1.00 45.42  ?  7008 ASN   B O      1 
ATOM   3306 C  CB     . ASN   A  1 210 ? 65.710  -28.120 -10.625 1.00 43.49  ?  7008 ASN   B CB     1 
ATOM   3307 C  CG     . ASN   A  1 210 ? 66.779  -29.015 -11.238 1.00 38.42  ?  7008 ASN   B CG     1 
ATOM   3308 O  OD1    . ASN   A  1 210 ? 66.817  -30.214 -10.982 1.00 41.23  ?  7008 ASN   B OD1    1 
ATOM   3309 N  ND2    . ASN   A  1 210 ? 67.625  -28.437 -12.082 1.00 44.65  ?  7008 ASN   B ND2    1 
ATOM   3310 H  H      . ASN   A  1 210 ? 68.128  -26.861 -9.204  1.00 49.20  ?  7008 ASN   B H      1 
ATOM   3311 H  HA     . ASN   A  1 210 ? 66.652  -26.297 -10.558 1.00 50.72  ?  7008 ASN   B HA     1 
ATOM   3312 H  HB2    . ASN   A  1 210 ? 65.199  -28.651 -9.995  1.00 52.71  ?  7008 ASN   B HB2    1 
ATOM   3313 H  HB3    . ASN   A  1 210 ? 65.134  -27.808 -11.340 1.00 52.71  ?  7008 ASN   B HB3    1 
ATOM   3314 H  HD21   . ASN   A  1 210 ? 67.552  -27.598 -12.257 1.00 54.10  ?  7008 ASN   B HD21   1 
ATOM   3315 H  HD22   . ASN   A  1 210 ? 68.246  -28.901 -12.454 1.00 54.10  ?  7008 ASN   B HD22   1 
ATOM   3316 N  N      . TYR   A  1 211 ? 65.268  -24.837 -9.180  1.00 44.14  ?  7009 TYR   B N      1 
ATOM   3317 C  CA     . TYR   A  1 211 ? 64.379  -23.982 -8.410  1.00 38.87  ?  7009 TYR   B CA     1 
ATOM   3318 C  C      . TYR   A  1 211 ? 62.997  -23.932 -9.053  1.00 39.41  ?  7009 TYR   B C      1 
ATOM   3319 O  O      . TYR   A  1 211 ? 62.860  -23.813 -10.278 1.00 40.28  ?  7009 TYR   B O      1 
ATOM   3320 C  CB     . TYR   A  1 211 ? 64.980  -22.583 -8.331  1.00 39.33  ?  7009 TYR   B CB     1 
ATOM   3321 C  CG     . TYR   A  1 211 ? 64.247  -21.557 -7.503  1.00 42.65  ?  7009 TYR   B CG     1 
ATOM   3322 C  CD1    . TYR   A  1 211 ? 63.859  -21.825 -6.194  1.00 43.42  ?  7009 TYR   B CD1    1 
ATOM   3323 C  CD2    . TYR   A  1 211 ? 63.959  -20.310 -8.030  1.00 43.16  ?  7009 TYR   B CD2    1 
ATOM   3324 C  CE1    . TYR   A  1 211 ? 63.207  -20.872 -5.429  1.00 47.34  ?  7009 TYR   B CE1    1 
ATOM   3325 C  CE2    . TYR   A  1 211 ? 63.303  -19.361 -7.285  1.00 46.76  ?  7009 TYR   B CE2    1 
ATOM   3326 C  CZ     . TYR   A  1 211 ? 62.932  -19.640 -5.985  1.00 46.37  ?  7009 TYR   B CZ     1 
ATOM   3327 O  OH     . TYR   A  1 211 ? 62.277  -18.676 -5.256  1.00 51.88  ?  7009 TYR   B OH     1 
ATOM   3328 H  H      . TYR   A  1 211 ? 65.831  -24.398 -9.659  1.00 53.49  ?  7009 TYR   B H      1 
ATOM   3329 H  HA     . TYR   A  1 211 ? 64.271  -24.328 -7.510  1.00 47.16  ?  7009 TYR   B HA     1 
ATOM   3330 H  HB2    . TYR   A  1 211 ? 65.871  -22.663 -7.955  1.00 47.71  ?  7009 TYR   B HB2    1 
ATOM   3331 H  HB3    . TYR   A  1 211 ? 65.032  -22.230 -9.233  1.00 47.71  ?  7009 TYR   B HB3    1 
ATOM   3332 H  HD1    . TYR   A  1 211 ? 64.040  -22.660 -5.826  1.00 52.62  ?  7009 TYR   B HD1    1 
ATOM   3333 H  HD2    . TYR   A  1 211 ? 64.213  -20.112 -8.902  1.00 52.31  ?  7009 TYR   B HD2    1 
ATOM   3334 H  HE1    . TYR   A  1 211 ? 62.958  -21.059 -4.553  1.00 57.33  ?  7009 TYR   B HE1    1 
ATOM   3335 H  HE2    . TYR   A  1 211 ? 63.109  -18.531 -7.656  1.00 56.63  ?  7009 TYR   B HE2    1 
ATOM   3336 H  HH     . TYR   A  1 211 ? 62.113  -18.963 -4.483  1.00 62.78  ?  7009 TYR   B HH     1 
ATOM   3337 N  N      . LEU   A  1 212 ? 61.966  -24.037 -8.218  1.00 46.68  ?  7010 LEU   B N      1 
ATOM   3338 C  CA     . LEU   A  1 212 ? 60.586  -24.075 -8.679  1.00 44.02  ?  7010 LEU   B CA     1 
ATOM   3339 C  C      . LEU   A  1 212 ? 59.791  -22.839 -8.287  1.00 44.50  ?  7010 LEU   B C      1 
ATOM   3340 O  O      . LEU   A  1 212 ? 58.636  -22.709 -8.703  1.00 48.78  ?  7010 LEU   B O      1 
ATOM   3341 C  CB     . LEU   A  1 212 ? 59.889  -25.325 -8.130  1.00 42.62  ?  7010 LEU   B CB     1 
ATOM   3342 C  CG     . LEU   A  1 212 ? 60.544  -26.669 -8.467  1.00 41.58  ?  7010 LEU   B CG     1 
ATOM   3343 C  CD1    . LEU   A  1 212 ? 59.807  -27.797 -7.783  1.00 45.74  ?  7010 LEU   B CD1    1 
ATOM   3344 C  CD2    . LEU   A  1 212 ? 60.607  -26.885 -9.970  1.00 46.03  ?  7010 LEU   B CD2    1 
ATOM   3345 H  H      . LEU   A  1 212 ? 62.044  -24.089 -7.363  1.00 56.54  ?  7010 LEU   B H      1 
ATOM   3346 H  HA     . LEU   A  1 212 ? 60.577  -24.133 -9.647  1.00 53.35  ?  7010 LEU   B HA     1 
ATOM   3347 H  HB2    . LEU   A  1 212 ? 59.861  -25.254 -7.163  1.00 51.67  ?  7010 LEU   B HB2    1 
ATOM   3348 H  HB3    . LEU   A  1 212 ? 58.987  -25.348 -8.487  1.00 51.67  ?  7010 LEU   B HB3    1 
ATOM   3349 H  HG     . LEU   A  1 212 ? 61.457  -26.665 -8.140  1.00 50.42  ?  7010 LEU   B HG     1 
ATOM   3350 H  HD11   . LEU   A  1 212 ? 60.241  -28.636 -8.004  1.00 55.41  ?  7010 LEU   B HD11   1 
ATOM   3351 H  HD12   . LEU   A  1 212 ? 59.831  -27.654 -6.824  1.00 55.41  ?  7010 LEU   B HD12   1 
ATOM   3352 H  HD13   . LEU   A  1 212 ? 58.888  -27.808 -8.094  1.00 55.41  ?  7010 LEU   B HD13   1 
ATOM   3353 H  HD21   . LEU   A  1 212 ? 60.936  -27.780 -10.147 1.00 55.75  ?  7010 LEU   B HD21   1 
ATOM   3354 H  HD22   . LEU   A  1 212 ? 59.717  -26.780 -10.342 1.00 55.75  ?  7010 LEU   B HD22   1 
ATOM   3355 H  HD23   . LEU   A  1 212 ? 61.207  -26.229 -10.359 1.00 55.75  ?  7010 LEU   B HD23   1 
ATOM   3356 N  N      . GLY   A  1 213 ? 60.367  -21.944 -7.485  1.00 48.18  ?  7011 GLY   B N      1 
ATOM   3357 C  CA     . GLY   A  1 213 ? 59.744  -20.680 -7.155  1.00 51.24  ?  7011 GLY   B CA     1 
ATOM   3358 C  C      . GLY   A  1 213 ? 58.639  -20.743 -6.130  1.00 52.77  ?  7011 GLY   B C      1 
ATOM   3359 O  O      . GLY   A  1 213 ? 58.093  -19.694 -5.769  1.00 64.27  ?  7011 GLY   B O      1 
ATOM   3360 H  H      . GLY   A  1 213 ? 61.135  -22.055 -7.114  1.00 58.34  ?  7011 GLY   B H      1 
ATOM   3361 H  HA2    . GLY   A  1 213 ? 60.427  -20.081 -6.812  1.00 62.01  ?  7011 GLY   B HA2    1 
ATOM   3362 H  HA3    . GLY   A  1 213 ? 59.370  -20.301 -7.965  1.00 62.01  ?  7011 GLY   B HA3    1 
ATOM   3363 N  N      . LYS   A  1 214 ? 58.288  -21.927 -5.656  1.00 54.01  ?  7012 LYS   B N      1 
ATOM   3364 C  CA     . LYS   A  1 214 ? 57.165  -22.123 -4.753  1.00 54.18  ?  7012 LYS   B CA     1 
ATOM   3365 C  C      . LYS   A  1 214 ? 57.500  -23.305 -3.866  1.00 51.25  ?  7012 LYS   B C      1 
ATOM   3366 O  O      . LYS   A  1 214 ? 58.343  -24.136 -4.232  1.00 56.04  ?  7012 LYS   B O      1 
ATOM   3367 C  CB     . LYS   A  1 214 ? 55.867  -22.378 -5.531  1.00 54.47  ?  7012 LYS   B CB     1 
ATOM   3368 C  CG     . LYS   A  1 214 ? 55.966  -23.593 -6.427  1.00 62.75  ?  7012 LYS   B CG     1 
ATOM   3369 C  CD     . LYS   A  1 214 ? 54.889  -23.644 -7.486  1.00 72.09  ?  7012 LYS   B CD     1 
ATOM   3370 C  CE     . LYS   A  1 214 ? 53.843  -24.702 -7.197  1.00 78.97  ?  7012 LYS   B CE     1 
ATOM   3371 N  NZ     . LYS   A  1 214 ? 52.947  -24.909 -8.371  1.00 77.89  ?  7012 LYS   B NZ     1 
ATOM   3372 H  H      . LYS   A  1 214 ? 58.698  -22.658 -5.849  1.00 65.33  ?  7012 LYS   B H      1 
ATOM   3373 H  HA     . LYS   A  1 214 ? 57.033  -21.341 -4.196  1.00 65.54  ?  7012 LYS   B HA     1 
ATOM   3374 H  HB2    . LYS   A  1 214 ? 55.143  -22.524 -4.902  1.00 65.88  ?  7012 LYS   B HB2    1 
ATOM   3375 H  HB3    . LYS   A  1 214 ? 55.673  -21.608 -6.087  1.00 65.88  ?  7012 LYS   B HB3    1 
ATOM   3376 H  HG2    . LYS   A  1 214 ? 56.825  -23.583 -6.877  1.00 75.82  ?  7012 LYS   B HG2    1 
ATOM   3377 H  HG3    . LYS   A  1 214 ? 55.886  -24.393 -5.883  1.00 75.82  ?  7012 LYS   B HG3    1 
ATOM   3378 H  HD2    . LYS   A  1 214 ? 54.443  -22.783 -7.527  1.00 87.03  ?  7012 LYS   B HD2    1 
ATOM   3379 H  HD3    . LYS   A  1 214 ? 55.295  -23.848 -8.343  1.00 87.03  ?  7012 LYS   B HD3    1 
ATOM   3380 H  HE2    . LYS   A  1 214 ? 54.282  -25.543 -6.995  1.00 95.28  ?  7012 LYS   B HE2    1 
ATOM   3381 H  HE3    . LYS   A  1 214 ? 53.300  -24.421 -6.444  1.00 95.28  ?  7012 LYS   B HE3    1 
ATOM   3382 H  HZ1    . LYS   A  1 214 ? 52.280  -25.455 -8.152  1.00 93.98  ?  7012 LYS   B HZ1    1 
ATOM   3383 H  HZ2    . LYS   A  1 214 ? 52.608  -24.130 -8.636  1.00 93.98  ?  7012 LYS   B HZ2    1 
ATOM   3384 H  HZ3    . LYS   A  1 214 ? 53.406  -25.269 -9.044  1.00 93.98  ?  7012 LYS   B HZ3    1 
ATOM   3385 N  N      . PRO   A  1 215 ? 56.895  -23.396 -2.680  1.00 50.87  ?  7013 PRO   B N      1 
ATOM   3386 C  CA     . PRO   A  1 215 ? 57.177  -24.555 -1.820  1.00 49.38  ?  7013 PRO   B CA     1 
ATOM   3387 C  C      . PRO   A  1 215 ? 56.648  -25.826 -2.471  1.00 49.79  ?  7013 PRO   B C      1 
ATOM   3388 O  O      . PRO   A  1 215 ? 55.466  -25.921 -2.807  1.00 62.36  ?  7013 PRO   B O      1 
ATOM   3389 C  CB     . PRO   A  1 215 ? 56.452  -24.226 -0.509  1.00 54.13  ?  7013 PRO   B CB     1 
ATOM   3390 C  CG     . PRO   A  1 215 ? 55.454  -23.160 -0.855  1.00 55.30  ?  7013 PRO   B CG     1 
ATOM   3391 C  CD     . PRO   A  1 215 ? 56.014  -22.413 -2.029  1.00 50.62  ?  7013 PRO   B CD     1 
ATOM   3392 H  HA     . PRO   A  1 215 ? 58.127  -24.641 -1.643  1.00 59.78  ?  7013 PRO   B HA     1 
ATOM   3393 H  HB2    . PRO   A  1 215 ? 56.006  -25.019 -0.173  1.00 65.48  ?  7013 PRO   B HB2    1 
ATOM   3394 H  HB3    . PRO   A  1 215 ? 57.090  -23.901 0.146   1.00 65.48  ?  7013 PRO   B HB3    1 
ATOM   3395 H  HG2    . PRO   A  1 215 ? 54.607  -23.572 -1.086  1.00 66.89  ?  7013 PRO   B HG2    1 
ATOM   3396 H  HG3    . PRO   A  1 215 ? 55.339  -22.566 -0.097  1.00 66.89  ?  7013 PRO   B HG3    1 
ATOM   3397 H  HD2    . PRO   A  1 215 ? 55.304  -22.136 -2.630  1.00 61.27  ?  7013 PRO   B HD2    1 
ATOM   3398 H  HD3    . PRO   A  1 215 ? 56.520  -21.639 -1.734  1.00 61.27  ?  7013 PRO   B HD3    1 
ATOM   3399 N  N      . ARG   A  1 216 ? 57.550  -26.778 -2.707  1.00 48.93  ?  7014 ARG   B N      1 
ATOM   3400 C  CA     . ARG   A  1 216 ? 57.181  -28.124 -3.118  1.00 45.45  ?  7014 ARG   B CA     1 
ATOM   3401 C  C      . ARG   A  1 216 ? 56.920  -29.002 -1.899  1.00 46.41  ?  7014 ARG   B C      1 
ATOM   3402 O  O      . ARG   A  1 216 ? 56.046  -29.877 -1.919  1.00 51.50  ?  7014 ARG   B O      1 
ATOM   3403 C  CB     . ARG   A  1 216 ? 58.309  -28.739 -3.957  1.00 44.63  ?  7014 ARG   B CB     1 
ATOM   3404 C  CG     . ARG   A  1 216 ? 57.903  -30.028 -4.651  1.00 50.72  ?  7014 ARG   B CG     1 
ATOM   3405 C  CD     . ARG   A  1 216 ? 59.119  -30.728 -5.216  1.00 50.25  ?  7014 ARG   B CD     1 
ATOM   3406 N  NE     . ARG   A  1 216 ? 60.112  -30.868 -4.167  1.00 59.98  ?  7014 ARG   B NE     1 
ATOM   3407 C  CZ     . ARG   A  1 216 ? 60.162  -31.889 -3.323  1.00 65.62  ?  7014 ARG   B CZ     1 
ATOM   3408 N  NH1    . ARG   A  1 216 ? 59.306  -32.896 -3.403  1.00 54.53  ?  7014 ARG   B NH1    1 
ATOM   3409 N  NH2    . ARG   A  1 216 ? 61.089  -31.894 -2.368  1.00 67.03  ?  7014 ARG   B NH2    1 
ATOM   3410 H  H      . ARG   A  1 216 ? 58.399  -26.664 -2.633  1.00 59.23  ?  7014 ARG   B H      1 
ATOM   3411 H  HA     . ARG   A  1 216 ? 56.384  -28.095 -3.670  1.00 55.06  ?  7014 ARG   B HA     1 
ATOM   3412 H  HB2    . ARG   A  1 216 ? 58.575  -28.103 -4.639  1.00 54.08  ?  7014 ARG   B HB2    1 
ATOM   3413 H  HB3    . ARG   A  1 216 ? 59.060  -28.936 -3.376  1.00 54.08  ?  7014 ARG   B HB3    1 
ATOM   3414 H  HG2    . ARG   A  1 216 ? 57.474  -30.619 -4.013  1.00 61.39  ?  7014 ARG   B HG2    1 
ATOM   3415 H  HG3    . ARG   A  1 216 ? 57.295  -29.827 -5.379  1.00 61.39  ?  7014 ARG   B HG3    1 
ATOM   3416 H  HD2    . ARG   A  1 216 ? 58.873  -31.609 -5.538  1.00 60.82  ?  7014 ARG   B HD2    1 
ATOM   3417 H  HD3    . ARG   A  1 216 ? 59.496  -30.203 -5.940  1.00 60.82  ?  7014 ARG   B HD3    1 
ATOM   3418 H  HE     . ARG   A  1 216 ? 60.705  -30.251 -4.088  1.00 72.50  ?  7014 ARG   B HE     1 
ATOM   3419 H  HH11   . ARG   A  1 216 ? 58.700  -32.897 -4.012  1.00 65.95  ?  7014 ARG   B HH11   1 
ATOM   3420 H  HH12   . ARG   A  1 216 ? 59.357  -33.548 -2.844  1.00 65.95  ?  7014 ARG   B HH12   1 
ATOM   3421 H  HH21   . ARG   A  1 216 ? 61.645  -31.241 -2.305  1.00 80.96  ?  7014 ARG   B HH21   1 
ATOM   3422 H  HH22   . ARG   A  1 216 ? 61.132  -32.551 -1.814  1.00 80.96  ?  7014 ARG   B HH22   1 
ATOM   3423 N  N      . GLU   A  1 217 ? 57.699  -28.780 -0.843  1.00 55.75  ?  7015 GLU   B N      1 
ATOM   3424 C  CA     . GLU   A  1 217 ? 57.524  -29.427 0.446   1.00 54.57  ?  7015 GLU   B CA     1 
ATOM   3425 C  C      . GLU   A  1 217 ? 57.837  -28.380 1.503   1.00 51.71  ?  7015 GLU   B C      1 
ATOM   3426 O  O      . GLU   A  1 217 ? 58.597  -27.443 1.251   1.00 52.76  ?  7015 GLU   B O      1 
ATOM   3427 C  CB     . GLU   A  1 217 ? 58.434  -30.648 0.606   1.00 52.24  ?  7015 GLU   B CB     1 
ATOM   3428 C  CG     . GLU   A  1 217 ? 59.888  -30.337 0.842   1.00 61.57  ?  7015 GLU   B CG     1 
ATOM   3429 C  CD     . GLU   A  1 217 ? 60.783  -31.547 0.721   1.00 79.27  ?  7015 GLU   B CD     1 
ATOM   3430 O  OE1    . GLU   A  1 217 ? 61.153  -31.944 -0.389  1.00 73.14  ?  7015 GLU   B OE1    1 
ATOM   3431 O  OE2    . GLU   A  1 217 ? 61.126  -32.125 1.754   1.00 73.97  ?  7015 GLU   B OE2    1 
ATOM   3432 H  H      . GLU   A  1 217 ? 58.364  -28.235 -0.851  1.00 67.42  ?  7015 GLU   B H      1 
ATOM   3433 H  HA     . GLU   A  1 217 ? 56.612  -29.741 0.555   1.00 66.01  ?  7015 GLU   B HA     1 
ATOM   3434 H  HB2    . GLU   A  1 217 ? 58.122  -31.166 1.364   1.00 63.21  ?  7015 GLU   B HB2    1 
ATOM   3435 H  HB3    . GLU   A  1 217 ? 58.379  -31.179 -0.204  1.00 63.21  ?  7015 GLU   B HB3    1 
ATOM   3436 H  HG2    . GLU   A  1 217 ? 60.180  -29.684 0.187   1.00 74.40  ?  7015 GLU   B HG2    1 
ATOM   3437 H  HG3    . GLU   A  1 217 ? 59.991  -29.978 1.737   1.00 74.40  ?  7015 GLU   B HG3    1 
ATOM   3438 N  N      . GLN   A  1 218 ? 57.236  -28.525 2.678   1.00 47.48  ?  7016 GLN   B N      1 
ATOM   3439 C  CA     . GLN   A  1 218 ? 57.370  -27.543 3.745   1.00 57.37  ?  7016 GLN   B CA     1 
ATOM   3440 C  C      . GLN   A  1 218 ? 58.429  -28.032 4.721   1.00 51.33  ?  7016 GLN   B C      1 
ATOM   3441 O  O      . GLN   A  1 218 ? 58.325  -29.148 5.240   1.00 57.04  ?  7016 GLN   B O      1 
ATOM   3442 C  CB     . GLN   A  1 218 ? 56.032  -27.334 4.455   1.00 56.05  ?  7016 GLN   B CB     1 
ATOM   3443 C  CG     . GLN   A  1 218 ? 55.084  -26.383 3.727   1.00 67.45  ?  7016 GLN   B CG     1 
ATOM   3444 C  CD     . GLN   A  1 218 ? 55.494  -24.923 3.809   1.00 78.06  ?  7016 GLN   B CD     1 
ATOM   3445 O  OE1    . GLN   A  1 218 ? 56.246  -24.531 4.691   1.00 88.79  ?  7016 GLN   B OE1    1 
ATOM   3446 N  NE2    . GLN   A  1 218 ? 54.977  -24.108 2.903   1.00 72.66  ?  7016 GLN   B NE2    1 
ATOM   3447 H  H      . GLN   A  1 218 ? 56.737  -29.195 2.883   1.00 57.50  ?  7016 GLN   B H      1 
ATOM   3448 H  HA     . GLN   A  1 218 ? 57.655  -26.692 3.379   1.00 69.36  ?  7016 GLN   B HA     1 
ATOM   3449 H  HB2    . GLN   A  1 218 ? 55.585  -28.191 4.537   1.00 67.78  ?  7016 GLN   B HB2    1 
ATOM   3450 H  HB3    . GLN   A  1 218 ? 56.202  -26.963 5.335   1.00 67.78  ?  7016 GLN   B HB3    1 
ATOM   3451 H  HG2    . GLN   A  1 218 ? 55.055  -26.630 2.789   1.00 81.46  ?  7016 GLN   B HG2    1 
ATOM   3452 H  HG3    . GLN   A  1 218 ? 54.200  -26.464 4.118   1.00 81.46  ?  7016 GLN   B HG3    1 
ATOM   3453 H  HE21   . GLN   A  1 218 ? 54.438  -24.414 2.307   1.00 87.72  ?  7016 GLN   B HE21   1 
ATOM   3454 H  HE22   . GLN   A  1 218 ? 55.181  -23.273 2.911   1.00 87.72  ?  7016 GLN   B HE22   1 
ATOM   3455 N  N      . ILE   A  1 219 ? 59.448  -27.210 4.962   1.00 53.69  ?  7017 ILE   B N      1 
ATOM   3456 C  CA     . ILE   A  1 219 ? 60.585  -27.596 5.782   1.00 46.28  ?  7017 ILE   B CA     1 
ATOM   3457 C  C      . ILE   A  1 219 ? 60.688  -26.641 6.956   1.00 42.50  ?  7017 ILE   B C      1 
ATOM   3458 O  O      . ILE   A  1 219 ? 60.702  -25.419 6.768   1.00 53.35  ?  7017 ILE   B O      1 
ATOM   3459 C  CB     . ILE   A  1 219 ? 61.894  -27.631 4.972   1.00 46.85  ?  7017 ILE   B CB     1 
ATOM   3460 C  CG1    . ILE   A  1 219 ? 61.807  -28.809 4.009   1.00 45.82  ?  7017 ILE   B CG1    1 
ATOM   3461 C  CG2    . ILE   A  1 219 ? 63.078  -27.755 5.898   1.00 45.11  ?  7017 ILE   B CG2    1 
ATOM   3462 C  CD1    . ILE   A  1 219 ? 62.995  -28.993 3.091   1.00 46.85  ?  7017 ILE   B CD1    1 
ATOM   3463 H  H      . ILE   A  1 219 ? 59.500  -26.408 4.655   1.00 64.94  ?  7017 ILE   B H      1 
ATOM   3464 H  HA     . ILE   A  1 219 ? 60.431  -28.486 6.136   1.00 56.05  ?  7017 ILE   B HA     1 
ATOM   3465 H  HB     . ILE   A  1 219 ? 62.012  -26.809 4.470   1.00 56.74  ?  7017 ILE   B HB     1 
ATOM   3466 H  HG12   . ILE   A  1 219 ? 61.717  -29.623 4.530   1.00 55.51  ?  7017 ILE   B HG12   1 
ATOM   3467 H  HG13   . ILE   A  1 219 ? 61.025  -28.687 3.448   1.00 55.51  ?  7017 ILE   B HG13   1 
ATOM   3468 H  HG21   . ILE   A  1 219 ? 63.859  -28.005 5.380   1.00 54.66  ?  7017 ILE   B HG21   1 
ATOM   3469 H  HG22   . ILE   A  1 219 ? 63.229  -26.901 6.333   1.00 54.66  ?  7017 ILE   B HG22   1 
ATOM   3470 H  HG23   . ILE   A  1 219 ? 62.890  -28.436 6.562   1.00 54.66  ?  7017 ILE   B HG23   1 
ATOM   3471 H  HD11   . ILE   A  1 219 ? 62.770  -29.646 2.410   1.00 56.75  ?  7017 ILE   B HD11   1 
ATOM   3472 H  HD12   . ILE   A  1 219 ? 63.207  -28.142 2.676   1.00 56.75  ?  7017 ILE   B HD12   1 
ATOM   3473 H  HD13   . ILE   A  1 219 ? 63.751  -29.305 3.612   1.00 56.75  ?  7017 ILE   B HD13   1 
ATOM   3474 N  N      . ASP   A  1 220 ? 60.696  -27.201 8.162   1.00 41.42  ?  7018 ASP   B N      1 
ATOM   3475 C  CA     . ASP   A  1 220 ? 61.051  -26.474 9.369   1.00 41.96  ?  7018 ASP   B CA     1 
ATOM   3476 C  C      . ASP   A  1 220 ? 62.574  -26.478 9.457   1.00 39.53  ?  7018 ASP   B C      1 
ATOM   3477 O  O      . ASP   A  1 220 ? 63.185  -27.534 9.647   1.00 46.24  ?  7018 ASP   B O      1 
ATOM   3478 C  CB     . ASP   A  1 220 ? 60.399  -27.134 10.585  1.00 44.12  ?  7018 ASP   B CB     1 
ATOM   3479 C  CG     . ASP   A  1 220 ? 60.757  -26.454 11.885  1.00 43.37  ?  7018 ASP   B CG     1 
ATOM   3480 O  OD1    . ASP   A  1 220 ? 61.915  -26.007 12.039  1.00 47.02  ?  7018 ASP   B OD1    1 
ATOM   3481 O  OD2    . ASP   A  1 220 ? 59.864  -26.360 12.752  1.00 56.99  ?  7018 ASP   B OD2    1 
ATOM   3482 H  H      . ASP   A  1 220 ? 60.494  -28.024 8.308   1.00 50.23  ?  7018 ASP   B H      1 
ATOM   3483 H  HA     . ASP   A  1 220 ? 60.738  -25.556 9.337   1.00 50.87  ?  7018 ASP   B HA     1 
ATOM   3484 H  HB2    . ASP   A  1 220 ? 59.435  -27.100 10.484  1.00 53.47  ?  7018 ASP   B HB2    1 
ATOM   3485 H  HB3    . ASP   A  1 220 ? 60.694  -28.057 10.639  1.00 53.47  ?  7018 ASP   B HB3    1 
ATOM   3486 N  N      . GLY   A  1 221 ? 63.186  -25.308 9.271   1.00 39.89  ?  7019 GLY   B N      1 
ATOM   3487 C  CA     . GLY   A  1 221 ? 64.630  -25.221 9.170   1.00 39.76  ?  7019 GLY   B CA     1 
ATOM   3488 C  C      . GLY   A  1 221 ? 65.371  -25.385 10.474  1.00 36.63  ?  7019 GLY   B C      1 
ATOM   3489 O  O      . GLY   A  1 221 ? 66.560  -25.723 10.453  1.00 40.22  ?  7019 GLY   B O      1 
ATOM   3490 H  H      . GLY   A  1 221 ? 62.783  -24.552 9.200   1.00 48.39  ?  7019 GLY   B H      1 
ATOM   3491 H  HA2    . GLY   A  1 221 ? 64.941  -25.912 8.565   1.00 48.24  ?  7019 GLY   B HA2    1 
ATOM   3492 H  HA3    . GLY   A  1 221 ? 64.864  -24.353 8.805   1.00 48.24  ?  7019 GLY   B HA3    1 
ATOM   3493 N  N      . TYR   A  1 222 ? 64.720  -25.115 11.611  1.00 46.12  ?  7020 TYR   B N      1 
ATOM   3494 C  CA     . TYR   A  1 222 ? 65.341  -25.439 12.893  1.00 44.97  ?  7020 TYR   B CA     1 
ATOM   3495 C  C      . TYR   A  1 222 ? 65.486  -26.945 13.040  1.00 42.93  ?  7020 TYR   B C      1 
ATOM   3496 O  O      . TYR   A  1 222 ? 66.546  -27.444 13.433  1.00 44.96  ?  7020 TYR   B O      1 
ATOM   3497 C  CB     . TYR   A  1 222 ? 64.523  -24.858 14.049  1.00 51.80  ?  7020 TYR   B CB     1 
ATOM   3498 C  CG     . TYR   A  1 222 ? 64.375  -23.346 13.936  1.00 42.37  ?  7020 TYR   B CG     1 
ATOM   3499 C  CD1    . TYR   A  1 222 ? 63.403  -22.803 13.119  1.00 49.82  ?  7020 TYR   B CD1    1 
ATOM   3500 C  CD2    . TYR   A  1 222 ? 65.217  -22.460 14.597  1.00 43.60  ?  7020 TYR   B CD2    1 
ATOM   3501 C  CE1    . TYR   A  1 222 ? 63.255  -21.445 12.979  1.00 47.33  ?  7020 TYR   B CE1    1 
ATOM   3502 C  CE2    . TYR   A  1 222 ? 65.064  -21.078 14.448  1.00 49.87  ?  7020 TYR   B CE2    1 
ATOM   3503 C  CZ     . TYR   A  1 222 ? 64.079  -20.597 13.642  1.00 57.64  ?  7020 TYR   B CZ     1 
ATOM   3504 O  OH     . TYR   A  1 222 ? 63.900  -19.251 13.488  1.00 60.91  ?  7020 TYR   B OH     1 
ATOM   3505 H  H      . TYR   A  1 222 ? 63.941  -24.754 11.663  1.00 55.86  ?  7020 TYR   B H      1 
ATOM   3506 H  HA     . TYR   A  1 222 ? 66.222  -25.035 12.933  1.00 54.49  ?  7020 TYR   B HA     1 
ATOM   3507 H  HB2    . TYR   A  1 222 ? 63.636  -25.251 14.042  1.00 62.68  ?  7020 TYR   B HB2    1 
ATOM   3508 H  HB3    . TYR   A  1 222 ? 64.968  -25.058 14.887  1.00 62.68  ?  7020 TYR   B HB3    1 
ATOM   3509 H  HD1    . TYR   A  1 222 ? 62.834  -23.372 12.651  1.00 60.30  ?  7020 TYR   B HD1    1 
ATOM   3510 H  HD2    . TYR   A  1 222 ? 65.891  -22.790 15.145  1.00 52.84  ?  7020 TYR   B HD2    1 
ATOM   3511 H  HE1    . TYR   A  1 222 ? 62.588  -21.106 12.428  1.00 57.32  ?  7020 TYR   B HE1    1 
ATOM   3512 H  HE2    . TYR   A  1 222 ? 65.632  -20.493 14.895  1.00 60.37  ?  7020 TYR   B HE2    1 
ATOM   3513 H  HH     . TYR   A  1 222 ? 64.499  -18.833 13.903  1.00 73.61  ?  7020 TYR   B HH     1 
ATOM   3514 N  N      . VAL   A  1 223 ? 64.427  -27.680 12.706  1.00 44.73  ?  7021 VAL   B N      1 
ATOM   3515 C  CA     . VAL   A  1 223 ? 64.455  -29.133 12.779  1.00 49.27  ?  7021 VAL   B CA     1 
ATOM   3516 C  C      . VAL   A  1 223 ? 65.440  -29.713 11.776  1.00 45.01  ?  7021 VAL   B C      1 
ATOM   3517 O  O      . VAL   A  1 223 ? 66.174  -30.657 12.094  1.00 40.85  ?  7021 VAL   B O      1 
ATOM   3518 C  CB     . VAL   A  1 223 ? 63.037  -29.689 12.555  1.00 43.76  ?  7021 VAL   B CB     1 
ATOM   3519 C  CG1    . VAL   A  1 223 ? 63.065  -31.198 12.541  1.00 42.82  ?  7021 VAL   B CG1    1 
ATOM   3520 C  CG2    . VAL   A  1 223 ? 62.109  -29.170 13.625  1.00 49.39  ?  7021 VAL   B CG2    1 
ATOM   3521 H  H      . VAL   A  1 223 ? 63.677  -27.358 12.433  1.00 54.20  ?  7021 VAL   B H      1 
ATOM   3522 H  HA     . VAL   A  1 223 ? 64.756  -29.388 13.665  1.00 59.65  ?  7021 VAL   B HA     1 
ATOM   3523 H  HB     . VAL   A  1 223 ? 62.701  -29.392 11.695  1.00 53.03  ?  7021 VAL   B HB     1 
ATOM   3524 H  HG11   . VAL   A  1 223 ? 62.158  -31.532 12.629  1.00 51.91  ?  7021 VAL   B HG11   1 
ATOM   3525 H  HG12   . VAL   A  1 223 ? 63.448  -31.499 11.702  1.00 51.91  ?  7021 VAL   B HG12   1 
ATOM   3526 H  HG13   . VAL   A  1 223 ? 63.606  -31.511 13.283  1.00 51.91  ?  7021 VAL   B HG13   1 
ATOM   3527 H  HG21   . VAL   A  1 223 ? 61.237  -29.580 13.513  1.00 59.79  ?  7021 VAL   B HG21   1 
ATOM   3528 H  HG22   . VAL   A  1 223 ? 62.472  -29.397 14.495  1.00 59.79  ?  7021 VAL   B HG22   1 
ATOM   3529 H  HG23   . VAL   A  1 223 ? 62.035  -28.207 13.539  1.00 59.79  ?  7021 VAL   B HG23   1 
ATOM   3530 N  N      . MET   A  1 224 ? 65.477  -29.166 10.554  1.00 41.86  ?  7022 MET   B N      1 
ATOM   3531 C  CA     . MET   A  1 224 ? 66.326  -29.749 9.529   1.00 44.01  ?  7022 MET   B CA     1 
ATOM   3532 C  C      . MET   A  1 224 ? 67.797  -29.571 9.887   1.00 41.07  ?  7022 MET   B C      1 
ATOM   3533 O  O      . MET   A  1 224 ? 68.604  -30.492 9.705   1.00 42.06  ?  7022 MET   B O      1 
ATOM   3534 C  CB     . MET   A  1 224 ? 66.034  -29.133 8.163   1.00 41.77  ?  7022 MET   B CB     1 
ATOM   3535 C  CG     . MET   A  1 224 ? 66.561  -29.952 6.999   1.00 37.17  ?  7022 MET   B CG     1 
ATOM   3536 S  SD     . MET   A  1 224 ? 65.986  -31.672 7.023   1.00 43.03  ?  7022 MET   B SD     1 
ATOM   3537 C  CE     . MET   A  1 224 ? 64.434  -31.524 6.165   1.00 39.92  ?  7022 MET   B CE     1 
ATOM   3538 H  H      . MET   A  1 224 ? 65.029  -28.475 10.306  1.00 50.76  ?  7022 MET   B H      1 
ATOM   3539 H  HA     . MET   A  1 224 ? 66.119  -30.695 9.466   1.00 53.34  ?  7022 MET   B HA     1 
ATOM   3540 H  HB2    . MET   A  1 224 ? 65.073  -29.051 8.056   1.00 50.65  ?  7022 MET   B HB2    1 
ATOM   3541 H  HB3    . MET   A  1 224 ? 66.448  -28.257 8.120   1.00 50.65  ?  7022 MET   B HB3    1 
ATOM   3542 H  HG2    . MET   A  1 224 ? 66.262  -29.549 6.169   1.00 45.12  ?  7022 MET   B HG2    1 
ATOM   3543 H  HG3    . MET   A  1 224 ? 67.530  -29.961 7.034   1.00 45.12  ?  7022 MET   B HG3    1 
ATOM   3544 H  HE1    . MET   A  1 224 ? 64.031  -32.403 6.088   1.00 48.42  ?  7022 MET   B HE1    1 
ATOM   3545 H  HE2    . MET   A  1 224 ? 63.850  -30.935 6.668   1.00 48.42  ?  7022 MET   B HE2    1 
ATOM   3546 H  HE3    . MET   A  1 224 ? 64.595  -31.156 5.282   1.00 48.42  ?  7022 MET   B HE3    1 
ATOM   3547 N  N      . HIS   A  1 225 ? 68.174  -28.404 10.414  1.00 38.30  ?  7023 HIS   B N      1 
ATOM   3548 C  CA     . HIS   A  1 225 ? 69.565  -28.234 10.810  1.00 40.95  ?  7023 HIS   B CA     1 
ATOM   3549 C  C      . HIS   A  1 225 ? 69.920  -29.216 11.922  1.00 44.49  ?  7023 HIS   B C      1 
ATOM   3550 O  O      . HIS   A  1 225 ? 71.022  -29.780 11.936  1.00 44.48  ?  7023 HIS   B O      1 
ATOM   3551 C  CB     . HIS   A  1 225 ? 69.854  -26.807 11.262  1.00 38.73  ?  7023 HIS   B CB     1 
ATOM   3552 C  CG     . HIS   A  1 225 ? 71.313  -26.537 11.423  1.00 36.24  ?  7023 HIS   B CG     1 
ATOM   3553 N  ND1    . HIS   A  1 225 ? 72.201  -26.693 10.385  1.00 38.23  ?  7023 HIS   B ND1    1 
ATOM   3554 C  CD2    . HIS   A  1 225 ? 72.050  -26.166 12.497  1.00 38.03  ?  7023 HIS   B CD2    1 
ATOM   3555 C  CE1    . HIS   A  1 225 ? 73.421  -26.396 10.804  1.00 39.15  ?  7023 HIS   B CE1    1 
ATOM   3556 N  NE2    . HIS   A  1 225 ? 73.358  -26.073 12.084  1.00 39.13  ?  7023 HIS   B NE2    1 
ATOM   3557 H  H      . HIS   A  1 225 ? 67.663  -27.725 10.546  1.00 46.49  ?  7023 HIS   B H      1 
ATOM   3558 H  HA     . HIS   A  1 225 ? 70.122  -28.402 10.034  1.00 49.66  ?  7023 HIS   B HA     1 
ATOM   3559 H  HB2    . HIS   A  1 225 ? 69.505  -26.189 10.601  1.00 47.00  ?  7023 HIS   B HB2    1 
ATOM   3560 H  HB3    . HIS   A  1 225 ? 69.424  -26.654 12.118  1.00 47.00  ?  7023 HIS   B HB3    1 
ATOM   3561 H  HD2    . HIS   A  1 225 ? 71.731  -26.005 13.356  1.00 46.16  ?  7023 HIS   B HD2    1 
ATOM   3562 H  HE1    . HIS   A  1 225 ? 74.193  -26.412 10.285  1.00 47.51  ?  7023 HIS   B HE1    1 
ATOM   3563 H  HE2    . HIS   A  1 225 ? 74.024  -25.842 12.577  1.00 47.48  ?  7023 HIS   B HE2    1 
ATOM   3564 N  N      . ALA   A  1 226 ? 68.990  -29.438 12.859  1.00 44.07  ?  7024 ALA   B N      1 
ATOM   3565 C  CA     . ALA   A  1 226 ? 69.203  -30.442 13.895  1.00 39.42  ?  7024 ALA   B CA     1 
ATOM   3566 C  C      . ALA   A  1 226 ? 69.319  -31.832 13.285  1.00 38.31  ?  7024 ALA   B C      1 
ATOM   3567 O  O      . ALA   A  1 226 ? 70.140  -32.644 13.730  1.00 40.49  ?  7024 ALA   B O      1 
ATOM   3568 C  CB     . ALA   A  1 226 ? 68.064  -30.402 14.914  1.00 40.02  ?  7024 ALA   B CB     1 
ATOM   3569 H  H      . ALA   A  1 226 ? 68.238  -29.024 12.914  1.00 53.41  ?  7024 ALA   B H      1 
ATOM   3570 H  HA     . ALA   A  1 226 ? 70.029  -30.240 14.361  1.00 47.83  ?  7024 ALA   B HA     1 
ATOM   3571 H  HB1    . ALA   A  1 226 ? 68.217  -31.086 15.585  1.00 48.54  ?  7024 ALA   B HB1    1 
ATOM   3572 H  HB2    . ALA   A  1 226 ? 68.046  -29.527 15.333  1.00 48.54  ?  7024 ALA   B HB2    1 
ATOM   3573 H  HB3    . ALA   A  1 226 ? 67.225  -30.568 14.457  1.00 48.54  ?  7024 ALA   B HB3    1 
ATOM   3574 N  N      . ASN   A  1 227 ? 68.488  -32.131 12.280  1.00 41.00  ?  7025 ASN   B N      1 
ATOM   3575 C  CA     . ASN   A  1 227 ? 68.649  -33.378 11.547  1.00 43.00  ?  7025 ASN   B CA     1 
ATOM   3576 C  C      . ASN   A  1 227 ? 70.034  -33.469 10.928  1.00 40.85  ?  7025 ASN   B C      1 
ATOM   3577 O  O      . ASN   A  1 227 ? 70.664  -34.535 10.942  1.00 39.29  ?  7025 ASN   B O      1 
ATOM   3578 C  CB     . ASN   A  1 227 ? 67.604  -33.478 10.440  1.00 38.72  ?  7025 ASN   B CB     1 
ATOM   3579 C  CG     . ASN   A  1 227 ? 66.209  -33.659 10.975  1.00 39.94  ?  7025 ASN   B CG     1 
ATOM   3580 O  OD1    . ASN   A  1 227 ? 66.029  -34.001 12.145  1.00 38.27  ?  7025 ASN   B OD1    1 
ATOM   3581 N  ND2    . ASN   A  1 227 ? 65.209  -33.424 10.126  1.00 42.95  ?  7025 ASN   B ND2    1 
ATOM   3582 H  H      . ASN   A  1 227 ? 67.838  -31.636 12.013  1.00 49.73  ?  7025 ASN   B H      1 
ATOM   3583 H  HA     . ASN   A  1 227 ? 68.524  -34.115 12.165  1.00 52.13  ?  7025 ASN   B HA     1 
ATOM   3584 H  HB2    . ASN   A  1 227 ? 67.621  -32.663 9.915   1.00 46.98  ?  7025 ASN   B HB2    1 
ATOM   3585 H  HB3    . ASN   A  1 227 ? 67.812  -34.240 9.877   1.00 46.98  ?  7025 ASN   B HB3    1 
ATOM   3586 H  HD21   . ASN   A  1 227 ? 64.394  -33.515 10.385  1.00 52.06  ?  7025 ASN   B HD21   1 
ATOM   3587 H  HD22   . ASN   A  1 227 ? 65.378  -33.183 9.318   1.00 52.06  ?  7025 ASN   B HD22   1 
ATOM   3588 N  N      . TYR   A  1 228 ? 70.506  -32.361 10.349  1.00 42.24  ?  7026 TYR   B N      1 
ATOM   3589 C  CA     . TYR   A  1 228 ? 71.796  -32.371 9.682   1.00 41.13  ?  7026 TYR   B CA     1 
ATOM   3590 C  C      . TYR   A  1 228 ? 72.916  -32.632 10.686  1.00 39.40  ?  7026 TYR   B C      1 
ATOM   3591 O  O      . TYR   A  1 228 ? 73.809  -33.452 10.433  1.00 37.98  ?  7026 TYR   B O      1 
ATOM   3592 C  CB     . TYR   A  1 228 ? 72.022  -31.047 8.950   1.00 37.40  ?  7026 TYR   B CB     1 
ATOM   3593 C  CG     . TYR   A  1 228 ? 73.475  -30.833 8.658   1.00 35.65  ?  7026 TYR   B CG     1 
ATOM   3594 C  CD1    . TYR   A  1 228 ? 74.069  -31.500 7.595   1.00 34.40  ?  7026 TYR   B CD1    1 
ATOM   3595 C  CD2    . TYR   A  1 228 ? 74.260  -30.015 9.452   1.00 39.80  ?  7026 TYR   B CD2    1 
ATOM   3596 C  CE1    . TYR   A  1 228 ? 75.388  -31.350 7.322   1.00 34.96  ?  7026 TYR   B CE1    1 
ATOM   3597 C  CE2    . TYR   A  1 228 ? 75.599  -29.853 9.179   1.00 39.39  ?  7026 TYR   B CE2    1 
ATOM   3598 C  CZ     . TYR   A  1 228 ? 76.157  -30.519 8.098   1.00 33.44  ?  7026 TYR   B CZ     1 
ATOM   3599 O  OH     . TYR   A  1 228 ? 77.496  -30.376 7.796   1.00 38.45  ?  7026 TYR   B OH     1 
ATOM   3600 H  H      . TYR   A  1 228 ? 70.100  -31.603 10.331  1.00 51.21  ?  7026 TYR   B H      1 
ATOM   3601 H  HA     . TYR   A  1 228 ? 71.807  -33.079 9.018   1.00 49.88  ?  7026 TYR   B HA     1 
ATOM   3602 H  HB2    . TYR   A  1 228 ? 71.538  -31.057 8.109   1.00 45.41  ?  7026 TYR   B HB2    1 
ATOM   3603 H  HB3    . TYR   A  1 228 ? 71.709  -30.315 9.504   1.00 45.41  ?  7026 TYR   B HB3    1 
ATOM   3604 H  HD1    . TYR   A  1 228 ? 73.553  -32.060 7.062   1.00 41.81  ?  7026 TYR   B HD1    1 
ATOM   3605 H  HD2    . TYR   A  1 228 ? 73.880  -29.571 10.175  1.00 48.28  ?  7026 TYR   B HD2    1 
ATOM   3606 H  HE1    . TYR   A  1 228 ? 75.771  -31.810 6.610   1.00 42.47  ?  7026 TYR   B HE1    1 
ATOM   3607 H  HE2    . TYR   A  1 228 ? 76.125  -29.302 9.713   1.00 47.79  ?  7026 TYR   B HE2    1 
ATOM   3608 H  HH     . TYR   A  1 228 ? 77.865  -29.869 8.356   1.00 46.66  ?  7026 TYR   B HH     1 
ATOM   3609 N  N      . ILE   A  1 229 ? 72.858  -31.978 11.852  1.00 40.19  ?  7027 ILE   B N      1 
ATOM   3610 C  CA     . ILE   A  1 229 ? 73.867  -32.199 12.888  1.00 43.74  ?  7027 ILE   B CA     1 
ATOM   3611 C  C      . ILE   A  1 229 ? 73.791  -33.626 13.413  1.00 40.55  ?  7027 ILE   B C      1 
ATOM   3612 O  O      . ILE   A  1 229 ? 74.822  -34.271 13.646  1.00 42.17  ?  7027 ILE   B O      1 
ATOM   3613 C  CB     . ILE   A  1 229 ? 73.716  -31.174 14.034  1.00 43.67  ?  7027 ILE   B CB     1 
ATOM   3614 C  CG1    . ILE   A  1 229 ? 74.055  -29.763 13.545  1.00 46.18  ?  7027 ILE   B CG1    1 
ATOM   3615 C  CG2    . ILE   A  1 229 ? 74.569  -31.595 15.221  1.00 43.11  ?  7027 ILE   B CG2    1 
ATOM   3616 C  CD1    . ILE   A  1 229 ? 75.430  -29.630 12.953  1.00 38.91  ?  7027 ILE   B CD1    1 
ATOM   3617 H  H      . ILE   A  1 229 ? 72.250  -31.408 12.064  1.00 48.76  ?  7027 ILE   B H      1 
ATOM   3618 H  HA     . ILE   A  1 229 ? 74.739  -32.069 12.485  1.00 53.00  ?  7027 ILE   B HA     1 
ATOM   3619 H  HB     . ILE   A  1 229 ? 72.792  -31.155 14.327  1.00 52.92  ?  7027 ILE   B HB     1 
ATOM   3620 H  HG12   . ILE   A  1 229 ? 73.414  -29.509 12.862  1.00 55.94  ?  7027 ILE   B HG12   1 
ATOM   3621 H  HG13   . ILE   A  1 229 ? 73.998  -29.152 14.297  1.00 55.94  ?  7027 ILE   B HG13   1 
ATOM   3622 H  HG21   . ILE   A  1 229 ? 74.709  -30.828 15.798  1.00 52.25  ?  7027 ILE   B HG21   1 
ATOM   3623 H  HG22   . ILE   A  1 229 ? 74.108  -32.296 15.708  1.00 52.25  ?  7027 ILE   B HG22   1 
ATOM   3624 H  HG23   . ILE   A  1 229 ? 75.422  -31.925 14.896  1.00 52.25  ?  7027 ILE   B HG23   1 
ATOM   3625 H  HD11   . ILE   A  1 229 ? 75.658  -28.689 12.893  1.00 47.21  ?  7027 ILE   B HD11   1 
ATOM   3626 H  HD12   . ILE   A  1 229 ? 76.065  -30.089 13.524  1.00 47.21  ?  7027 ILE   B HD12   1 
ATOM   3627 H  HD13   . ILE   A  1 229 ? 75.432  -30.028 12.068  1.00 47.21  ?  7027 ILE   B HD13   1 
ATOM   3628 N  N      . PHE   A  1 230 ? 72.575  -34.133 13.624  1.00 44.35  ?  7028 PHE   B N      1 
ATOM   3629 C  CA     . PHE   A  1 230 ? 72.424  -35.515 14.059  1.00 42.67  ?  7028 PHE   B CA     1 
ATOM   3630 C  C      . PHE   A  1 230 ? 73.109  -36.465 13.095  1.00 38.76  ?  7028 PHE   B C      1 
ATOM   3631 O  O      . PHE   A  1 230 ? 73.813  -37.387 13.514  1.00 40.84  ?  7028 PHE   B O      1 
ATOM   3632 C  CB     . PHE   A  1 230 ? 70.947  -35.876 14.201  1.00 40.57  ?  7028 PHE   B CB     1 
ATOM   3633 C  CG     . PHE   A  1 230 ? 70.723  -37.302 14.571  1.00 47.81  ?  7028 PHE   B CG     1 
ATOM   3634 C  CD1    . PHE   A  1 230 ? 71.021  -37.759 15.852  1.00 40.08  ?  7028 PHE   B CD1    1 
ATOM   3635 C  CD2    . PHE   A  1 230 ? 70.212  -38.189 13.646  1.00 46.65  ?  7028 PHE   B CD2    1 
ATOM   3636 C  CE1    . PHE   A  1 230 ? 70.821  -39.083 16.202  1.00 43.63  ?  7028 PHE   B CE1    1 
ATOM   3637 C  CE2    . PHE   A  1 230 ? 70.005  -39.505 13.980  1.00 47.93  ?  7028 PHE   B CE2    1 
ATOM   3638 C  CZ     . PHE   A  1 230 ? 70.314  -39.958 15.272  1.00 43.21  ?  7028 PHE   B CZ     1 
ATOM   3639 H  H      . PHE   A  1 230 ? 71.837  -33.704 13.523  1.00 53.75  ?  7028 PHE   B H      1 
ATOM   3640 H  HA     . PHE   A  1 230 ? 72.837  -35.609 14.932  1.00 51.73  ?  7028 PHE   B HA     1 
ATOM   3641 H  HB2    . PHE   A  1 230 ? 70.554  -35.323 14.894  1.00 49.20  ?  7028 PHE   B HB2    1 
ATOM   3642 H  HB3    . PHE   A  1 230 ? 70.502  -35.715 13.354  1.00 49.20  ?  7028 PHE   B HB3    1 
ATOM   3643 H  HD1    . PHE   A  1 230 ? 71.359  -37.165 16.483  1.00 48.62  ?  7028 PHE   B HD1    1 
ATOM   3644 H  HD2    . PHE   A  1 230 ? 70.006  -37.893 12.789  1.00 56.50  ?  7028 PHE   B HD2    1 
ATOM   3645 H  HE1    . PHE   A  1 230 ? 71.028  -39.378 17.059  1.00 52.87  ?  7028 PHE   B HE1    1 
ATOM   3646 H  HE2    . PHE   A  1 230 ? 69.661  -40.096 13.350  1.00 58.04  ?  7028 PHE   B HE2    1 
ATOM   3647 H  HZ     . PHE   A  1 230 ? 70.175  -40.849 15.498  1.00 52.37  ?  7028 PHE   B HZ     1 
ATOM   3648 N  N      . TRP   A  1 231 ? 72.927  -36.245 11.796  1.00 46.56  ?  7029 TRP   B N      1 
ATOM   3649 C  CA     . TRP   A  1 231 ? 73.587  -37.083 10.809  1.00 37.66  ?  7029 TRP   B CA     1 
ATOM   3650 C  C      . TRP   A  1 231 ? 75.101  -36.989 10.949  1.00 37.96  ?  7029 TRP   B C      1 
ATOM   3651 O  O      . TRP   A  1 231 ? 75.792  -38.011 11.052  1.00 39.06  ?  7029 TRP   B O      1 
ATOM   3652 C  CB     . TRP   A  1 231 ? 73.143  -36.677 9.404   1.00 38.34  ?  7029 TRP   B CB     1 
ATOM   3653 C  CG     . TRP   A  1 231 ? 73.992  -37.245 8.331   1.00 35.39  ?  7029 TRP   B CG     1 
ATOM   3654 C  CD1    . TRP   A  1 231 ? 74.261  -38.563 8.120   1.00 40.91  ?  7029 TRP   B CD1    1 
ATOM   3655 C  CD2    . TRP   A  1 231 ? 74.679  -36.526 7.306   1.00 40.61  ?  7029 TRP   B CD2    1 
ATOM   3656 N  NE1    . TRP   A  1 231 ? 75.072  -38.711 7.028   1.00 43.00  ?  7029 TRP   B NE1    1 
ATOM   3657 C  CE2    . TRP   A  1 231 ? 75.344  -37.474 6.506   1.00 39.93  ?  7029 TRP   B CE2    1 
ATOM   3658 C  CE3    . TRP   A  1 231 ? 74.793  -35.176 6.984   1.00 38.31  ?  7029 TRP   B CE3    1 
ATOM   3659 C  CZ2    . TRP   A  1 231 ? 76.118  -37.115 5.419   1.00 41.22  ?  7029 TRP   B CZ2    1 
ATOM   3660 C  CZ3    . TRP   A  1 231 ? 75.561  -34.822 5.907   1.00 39.34  ?  7029 TRP   B CZ3    1 
ATOM   3661 C  CH2    . TRP   A  1 231 ? 76.208  -35.784 5.129   1.00 38.04  ?  7029 TRP   B CH2    1 
ATOM   3662 H  H      . TRP   A  1 231 ? 72.432  -35.624 11.466  1.00 56.39  ?  7029 TRP   B H      1 
ATOM   3663 H  HA     . TRP   A  1 231 ? 73.326  -38.007 10.948  1.00 45.71  ?  7029 TRP   B HA     1 
ATOM   3664 H  HB2    . TRP   A  1 231 ? 72.235  -36.987 9.260   1.00 46.54  ?  7029 TRP   B HB2    1 
ATOM   3665 H  HB3    . TRP   A  1 231 ? 73.179  -35.710 9.331   1.00 46.54  ?  7029 TRP   B HB3    1 
ATOM   3666 H  HD1    . TRP   A  1 231 ? 73.939  -39.262 8.642   1.00 49.62  ?  7029 TRP   B HD1    1 
ATOM   3667 H  HE1    . TRP   A  1 231 ? 75.365  -39.458 6.720   1.00 52.12  ?  7029 TRP   B HE1    1 
ATOM   3668 H  HE3    . TRP   A  1 231 ? 74.356  -34.529 7.490   1.00 46.50  ?  7029 TRP   B HE3    1 
ATOM   3669 H  HZ2    . TRP   A  1 231 ? 76.559  -37.754 4.906   1.00 49.99  ?  7029 TRP   B HZ2    1 
ATOM   3670 H  HZ3    . TRP   A  1 231 ? 75.655  -33.923 5.690   1.00 47.73  ?  7029 TRP   B HZ3    1 
ATOM   3671 H  HH2    . TRP   A  1 231 ? 76.712  -35.511 4.396   1.00 46.17  ?  7029 TRP   B HH2    1 
ATOM   3672 N  N      . ARG   A  1 232 ? 75.639  -35.764 10.954  1.00 40.15  ?  7030 ARG   B N      1 
ATOM   3673 C  CA     . ARG   A  1 232 ? 77.089  -35.599 11.087  1.00 40.79  ?  7030 ARG   B CA     1 
ATOM   3674 C  C      . ARG   A  1 232 ? 77.568  -36.239 12.388  1.00 38.96  ?  7030 ARG   B C      1 
ATOM   3675 O  O      . ARG   A  1 232 ? 78.621  -36.892 12.418  1.00 40.39  ?  7030 ARG   B O      1 
ATOM   3676 C  CB     . ARG   A  1 232 ? 77.453  -34.115 11.072  1.00 40.64  ?  7030 ARG   B CB     1 
ATOM   3677 C  CG     . ARG   A  1 232 ? 77.143  -33.376 9.793   1.00 36.87  ?  7030 ARG   B CG     1 
ATOM   3678 C  CD     . ARG   A  1 232 ? 77.721  -34.049 8.572   1.00 33.33  ?  7030 ARG   B CD     1 
ATOM   3679 N  NE     . ARG   A  1 232 ? 79.125  -34.424 8.758   1.00 40.50  ?  7030 ARG   B NE     1 
ATOM   3680 C  CZ     . ARG   A  1 232 ? 80.158  -33.613 8.627   1.00 35.93  ?  7030 ARG   B CZ     1 
ATOM   3681 N  NH1    . ARG   A  1 232 ? 79.996  -32.326 8.363   1.00 39.77  ?  7030 ARG   B NH1    1 
ATOM   3682 N  NH2    . ARG   A  1 232 ? 81.388  -34.094 8.775   1.00 43.42  ?  7030 ARG   B NH2    1 
ATOM   3683 H  H      . ARG   A  1 232 ? 75.197  -35.030 10.883  1.00 48.70  ?  7030 ARG   B H      1 
ATOM   3684 H  HA     . ARG   A  1 232 ? 77.532  -36.024 10.336  1.00 49.47  ?  7030 ARG   B HA     1 
ATOM   3685 H  HB2    . ARG   A  1 232 ? 76.964  -33.675 11.784  1.00 49.29  ?  7030 ARG   B HB2    1 
ATOM   3686 H  HB3    . ARG   A  1 232 ? 78.408  -34.035 11.225  1.00 49.29  ?  7030 ARG   B HB3    1 
ATOM   3687 H  HG2    . ARG   A  1 232 ? 76.180  -33.329 9.681   1.00 44.76  ?  7030 ARG   B HG2    1 
ATOM   3688 H  HG3    . ARG   A  1 232 ? 77.515  -32.482 9.846   1.00 44.76  ?  7030 ARG   B HG3    1 
ATOM   3689 H  HD2    . ARG   A  1 232 ? 77.216  -34.856 8.383   1.00 40.52  ?  7030 ARG   B HD2    1 
ATOM   3690 H  HD3    . ARG   A  1 232 ? 77.668  -33.441 7.818   1.00 40.52  ?  7030 ARG   B HD3    1 
ATOM   3691 H  HE     . ARG   A  1 232 ? 79.290  -35.241 8.971   1.00 49.12  ?  7030 ARG   B HE     1 
ATOM   3692 H  HH11   . ARG   A  1 232 ? 79.204  -32.002 8.273   1.00 48.25  ?  7030 ARG   B HH11   1 
ATOM   3693 H  HH12   . ARG   A  1 232 ? 80.682  -31.814 8.281   1.00 48.25  ?  7030 ARG   B HH12   1 
ATOM   3694 H  HH21   . ARG   A  1 232 ? 81.505  -34.927 8.954   1.00 52.63  ?  7030 ARG   B HH21   1 
ATOM   3695 H  HH22   . ARG   A  1 232 ? 82.067  -33.573 8.691   1.00 52.63  ?  7030 ARG   B HH22   1 
ATOM   3696 N  N      . ASN   A  1 233 ? 76.806  -36.068 13.471  1.00 42.21  ?  7031 ASN   B N      1 
ATOM   3697 C  CA     . ASN   A  1 233 ? 77.230  -36.575 14.774  1.00 41.36  ?  7031 ASN   B CA     1 
ATOM   3698 C  C      . ASN   A  1 233 ? 77.299  -38.093 14.794  1.00 40.44  ?  7031 ASN   B C      1 
ATOM   3699 O  O      . ASN   A  1 233 ? 78.113  -38.665 15.527  1.00 47.41  ?  7031 ASN   B O      1 
ATOM   3700 C  CB     . ASN   A  1 233 ? 76.281  -36.081 15.866  1.00 35.48  ?  7031 ASN   B CB     1 
ATOM   3701 C  CG     . ASN   A  1 233 ? 76.715  -34.772 16.472  1.00 38.62  ?  7031 ASN   B CG     1 
ATOM   3702 O  OD1    . ASN   A  1 233 ? 77.818  -34.298 16.219  1.00 46.94  ?  7031 ASN   B OD1    1 
ATOM   3703 N  ND2    . ASN   A  1 233 ? 75.844  -34.165 17.270  1.00 53.13  ?  7031 ASN   B ND2    1 
ATOM   3704 H  H      . ASN   A  1 233 ? 76.046  -35.665 13.478  1.00 51.17  ?  7031 ASN   B H      1 
ATOM   3705 H  HA     . ASN   A  1 233 ? 78.116  -36.231 14.963  1.00 50.16  ?  7031 ASN   B HA     1 
ATOM   3706 H  HB2    . ASN   A  1 233 ? 75.398  -35.955 15.484  1.00 43.10  ?  7031 ASN   B HB2    1 
ATOM   3707 H  HB3    . ASN   A  1 233 ? 76.244  -36.741 16.575  1.00 43.10  ?  7031 ASN   B HB3    1 
ATOM   3708 H  HD21   . ASN   A  1 233 ? 76.048  -33.415 17.639  1.00 64.28  ?  7031 ASN   B HD21   1 
ATOM   3709 H  HD22   . ASN   A  1 233 ? 75.075  -34.522 17.418  1.00 64.28  ?  7031 ASN   B HD22   1 
ATOM   3710 N  N      . THR   A  1 234 ? 76.442  -38.767 14.030  1.00 45.87  ?  7032 THR   B N      1 
ATOM   3711 C  CA     . THR   A  1 234 ? 76.392  -40.219 14.087  1.00 42.22  ?  7032 THR   B CA     1 
ATOM   3712 C  C      . THR   A  1 234 ? 76.981  -40.916 12.872  1.00 40.96  ?  7032 THR   B C      1 
ATOM   3713 O  O      . THR   A  1 234 ? 76.906  -42.146 12.786  1.00 45.78  ?  7032 THR   B O      1 
ATOM   3714 C  CB     . THR   A  1 234 ? 74.947  -40.715 14.259  1.00 38.88  ?  7032 THR   B CB     1 
ATOM   3715 O  OG1    . THR   A  1 234 ? 74.141  -40.259 13.174  1.00 44.41  ?  7032 THR   B OG1    1 
ATOM   3716 C  CG2    . THR   A  1 234 ? 74.357  -40.216 15.552  1.00 39.70  ?  7032 THR   B CG2    1 
ATOM   3717 H  H      . THR   A  1 234 ? 75.888  -38.407 13.479  1.00 55.56  ?  7032 THR   B H      1 
ATOM   3718 H  HA     . THR   A  1 234 ? 76.910  -40.476 14.866  1.00 51.19  ?  7032 THR   B HA     1 
ATOM   3719 H  HB     . THR   A  1 234 ? 74.950  -41.685 14.275  1.00 47.18  ?  7032 THR   B HB     1 
ATOM   3720 H  HG1    . THR   A  1 234 ? 74.107  -39.419 13.175  1.00 53.82  ?  7032 THR   B HG1    1 
ATOM   3721 H  HG21   . THR   A  1 234 ? 73.459  -40.565 15.664  1.00 48.16  ?  7032 THR   B HG21   1 
ATOM   3722 H  HG22   . THR   A  1 234 ? 74.903  -40.507 16.300  1.00 48.16  ?  7032 THR   B HG22   1 
ATOM   3723 H  HG23   . THR   A  1 234 ? 74.321  -39.247 15.548  1.00 48.16  ?  7032 THR   B HG23   1 
ATOM   3724 N  N      . ASN   A  1 235 ? 77.569  -40.184 11.935  1.00 44.35  ?  7033 ASN   B N      1 
ATOM   3725 C  CA     . ASN   A  1 235 ? 78.115  -40.771 10.713  1.00 43.69  ?  7033 ASN   B CA     1 
ATOM   3726 C  C      . ASN   A  1 235 ? 79.491  -40.194 10.441  1.00 41.96  ?  7033 ASN   B C      1 
ATOM   3727 O  O      . ASN   A  1 235 ? 79.641  -39.239 9.662   1.00 52.77  ?  7033 ASN   B O      1 
ATOM   3728 C  CB     . ASN   A  1 235 ? 77.183  -40.529 9.538   1.00 44.51  ?  7033 ASN   B CB     1 
ATOM   3729 C  CG     . ASN   A  1 235 ? 75.944  -41.369 9.606   1.00 43.83  ?  7033 ASN   B CG     1 
ATOM   3730 O  OD1    . ASN   A  1 235 ? 75.855  -42.424 8.978   1.00 50.79  ?  7033 ASN   B OD1    1 
ATOM   3731 N  ND2    . ASN   A  1 235 ? 74.996  -40.938 10.423  1.00 49.32  ?  7033 ASN   B ND2    1 
ATOM   3732 H  H      . ASN   A  1 235 ? 77.667  -39.331 11.983  1.00 53.74  ?  7033 ASN   B H      1 
ATOM   3733 H  HA     . ASN   A  1 235 ? 78.221  -41.725 10.848  1.00 52.94  ?  7033 ASN   B HA     1 
ATOM   3734 H  HB2    . ASN   A  1 235 ? 76.915  -39.597 9.532   1.00 53.93  ?  7033 ASN   B HB2    1 
ATOM   3735 H  HB3    . ASN   A  1 235 ? 77.649  -40.746 8.714   1.00 53.93  ?  7033 ASN   B HB3    1 
ATOM   3736 H  HD21   . ASN   A  1 235 ? 74.262  -41.381 10.502  1.00 59.71  ?  7033 ASN   B HD21   1 
ATOM   3737 H  HD22   . ASN   A  1 235 ? 75.113  -40.216 10.875  1.00 59.71  ?  7033 ASN   B HD22   1 
ATOM   3738 N  N      . PRO   A  1 236 ? 80.523  -40.761 11.059  1.00 44.26  ?  7034 PRO   B N      1 
ATOM   3739 C  CA     . PRO   A  1 236 ? 81.886  -40.334 10.737  1.00 46.39  ?  7034 PRO   B CA     1 
ATOM   3740 C  C      . PRO   A  1 236 ? 82.136  -40.516 9.248   1.00 42.57  ?  7034 PRO   B C      1 
ATOM   3741 O  O      . PRO   A  1 236 ? 81.730  -41.513 8.644   1.00 49.82  ?  7034 PRO   B O      1 
ATOM   3742 C  CB     . PRO   A  1 236 ? 82.768  -41.249 11.592  1.00 51.40  ?  7034 PRO   B CB     1 
ATOM   3743 C  CG     . PRO   A  1 236 ? 81.853  -41.805 12.662  1.00 53.73  ?  7034 PRO   B CG     1 
ATOM   3744 C  CD     . PRO   A  1 236 ? 80.504  -41.911 11.978  1.00 47.42  ?  7034 PRO   B CD     1 
ATOM   3745 H  HA     . PRO   A  1 236 ? 82.051  -39.415 11.000  1.00 56.20  ?  7034 PRO   B HA     1 
ATOM   3746 H  HB2    . PRO   A  1 236 ? 83.131  -41.962 11.043  1.00 62.21  ?  7034 PRO   B HB2    1 
ATOM   3747 H  HB3    . PRO   A  1 236 ? 83.489  -40.734 11.987  1.00 62.21  ?  7034 PRO   B HB3    1 
ATOM   3748 H  HG2    . PRO   A  1 236 ? 82.167  -42.676 12.952  1.00 65.00  ?  7034 PRO   B HG2    1 
ATOM   3749 H  HG3    . PRO   A  1 236 ? 81.815  -41.198 13.418  1.00 65.00  ?  7034 PRO   B HG3    1 
ATOM   3750 H  HD2    . PRO   A  1 236 ? 80.425  -42.746 11.489  1.00 57.42  ?  7034 PRO   B HD2    1 
ATOM   3751 H  HD3    . PRO   A  1 236 ? 79.780  -41.833 12.619  1.00 57.42  ?  7034 PRO   B HD3    1 
ATOM   3752 N  N      . ILE   A  1 237 ? 82.779  -39.520 8.651   1.00 45.23  ?  7035 ILE   B N      1 
ATOM   3753 C  CA     . ILE   A  1 237 ? 83.155  -39.555 7.249   1.00 44.34  ?  7035 ILE   B CA     1 
ATOM   3754 C  C      . ILE   A  1 237 ? 84.671  -39.583 7.196   1.00 37.38  ?  7035 ILE   B C      1 
ATOM   3755 O  O      . ILE   A  1 237 ? 85.337  -38.717 7.776   1.00 45.21  ?  7035 ILE   B O      1 
ATOM   3756 C  CB     . ILE   A  1 237 ? 82.562  -38.378 6.458   1.00 42.97  ?  7035 ILE   B CB     1 
ATOM   3757 C  CG1    . ILE   A  1 237 ? 81.036  -38.446 6.534   1.00 39.89  ?  7035 ILE   B CG1    1 
ATOM   3758 C  CG2    . ILE   A  1 237 ? 83.062  -38.414 5.026   1.00 40.68  ?  7035 ILE   B CG2    1 
ATOM   3759 C  CD1    . ILE   A  1 237 ? 80.334  -37.190 6.139   1.00 44.13  ?  7035 ILE   B CD1    1 
ATOM   3760 H  H      . ILE   A  1 237 ? 83.014  -38.796 9.051   1.00 54.80  ?  7035 ILE   B H      1 
ATOM   3761 H  HA     . ILE   A  1 237 ? 82.820  -40.366 6.835   1.00 53.73  ?  7035 ILE   B HA     1 
ATOM   3762 H  HB     . ILE   A  1 237 ? 82.849  -37.536 6.844   1.00 52.08  ?  7035 ILE   B HB     1 
ATOM   3763 H  HG12   . ILE   A  1 237 ? 80.729  -39.150 5.942   1.00 48.39  ?  7035 ILE   B HG12   1 
ATOM   3764 H  HG13   . ILE   A  1 237 ? 80.782  -38.647 7.448   1.00 48.39  ?  7035 ILE   B HG13   1 
ATOM   3765 H  HG21   . ILE   A  1 237 ? 82.548  -37.784 4.496   1.00 49.34  ?  7035 ILE   B HG21   1 
ATOM   3766 H  HG22   . ILE   A  1 237 ? 84.000  -38.169 5.013   1.00 49.34  ?  7035 ILE   B HG22   1 
ATOM   3767 H  HG23   . ILE   A  1 237 ? 82.949  -39.310 4.674   1.00 49.34  ?  7035 ILE   B HG23   1 
ATOM   3768 H  HD11   . ILE   A  1 237 ? 79.380  -37.305 6.272   1.00 53.47  ?  7035 ILE   B HD11   1 
ATOM   3769 H  HD12   . ILE   A  1 237 ? 80.659  -36.460 6.690   1.00 53.47  ?  7035 ILE   B HD12   1 
ATOM   3770 H  HD13   . ILE   A  1 237 ? 80.518  -37.006 5.205   1.00 53.47  ?  7035 ILE   B HD13   1 
ATOM   3771 N  N      . GLN   A  1 238 ? 85.209  -40.610 6.542   1.00 47.77  ?  7036 GLN   B N      1 
ATOM   3772 C  CA     . GLN   A  1 238 ? 86.653  -40.776 6.422   1.00 52.77  ?  7036 GLN   B CA     1 
ATOM   3773 C  C      . GLN   A  1 238 ? 87.213  -39.721 5.481   1.00 42.54  ?  7036 GLN   B C      1 
ATOM   3774 O  O      . GLN   A  1 238 ? 86.828  -39.653 4.309   1.00 44.35  ?  7036 GLN   B O      1 
ATOM   3775 C  CB     . GLN   A  1 238 ? 86.980  -42.189 5.927   1.00 58.70  ?  7036 GLN   B CB     1 
ATOM   3776 C  CG     . GLN   A  1 238 ? 88.383  -42.383 5.351   1.00 70.04  ?  7036 GLN   B CG     1 
ATOM   3777 C  CD     . GLN   A  1 238 ? 88.579  -43.741 4.680   1.00 84.66  ?  7036 GLN   B CD     1 
ATOM   3778 O  OE1    . GLN   A  1 238 ? 87.826  -44.683 4.898   1.00 76.90  ?  7036 GLN   B OE1    1 
ATOM   3779 N  NE2    . GLN   A  1 238 ? 89.599  -43.838 3.861   1.00 87.30  ?  7036 GLN   B NE2    1 
ATOM   3780 H  H      . GLN   A  1 238 ? 84.755  -41.229 6.156   1.00 57.85  ?  7036 GLN   B H      1 
ATOM   3781 H  HA     . GLN   A  1 238 ? 87.070  -40.660 7.290   1.00 63.85  ?  7036 GLN   B HA     1 
ATOM   3782 H  HB2    . GLN   A  1 238 ? 86.889  -42.801 6.674   1.00 70.96  ?  7036 GLN   B HB2    1 
ATOM   3783 H  HB3    . GLN   A  1 238 ? 86.348  -42.420 5.229   1.00 70.96  ?  7036 GLN   B HB3    1 
ATOM   3784 H  HG2    . GLN   A  1 238 ? 88.547  -41.696 4.686   1.00 84.57  ?  7036 GLN   B HG2    1 
ATOM   3785 H  HG3    . GLN   A  1 238 ? 89.031  -42.310 6.070   1.00 84.57  ?  7036 GLN   B HG3    1 
ATOM   3786 H  HE21   . GLN   A  1 238 ? 90.110  -43.160 3.729   1.00 105.28 ?  7036 GLN   B HE21   1 
ATOM   3787 H  HE22   . GLN   A  1 238 ? 89.756  -44.581 3.456   1.00 105.28 ?  7036 GLN   B HE22   1 
ATOM   3788 N  N      . LEU   A  1 239 ? 88.101  -38.880 6.004   1.00 45.31  ?  7037 LEU   B N      1 
ATOM   3789 C  CA     . LEU   A  1 239 ? 88.817  -37.925 5.176   1.00 43.46  ?  7037 LEU   B CA     1 
ATOM   3790 C  C      . LEU   A  1 239 ? 89.377  -38.603 3.938   1.00 38.04  ?  7037 LEU   B C      1 
ATOM   3791 O  O      . LEU   A  1 239 ? 90.010  -39.657 4.030   1.00 48.63  ?  7037 LEU   B O      1 
ATOM   3792 C  CB     . LEU   A  1 239 ? 89.943  -37.300 5.983   1.00 37.88  ?  7037 LEU   B CB     1 
ATOM   3793 C  CG     . LEU   A  1 239 ? 89.495  -36.228 6.969   1.00 45.97  ?  7037 LEU   B CG     1 
ATOM   3794 C  CD1    . LEU   A  1 239 ? 90.537  -36.060 8.019   1.00 52.86  ?  7037 LEU   B CD1    1 
ATOM   3795 C  CD2    . LEU   A  1 239 ? 89.263  -34.938 6.187   1.00 44.24  ?  7037 LEU   B CD2    1 
ATOM   3796 H  H      . LEU   A  1 239 ? 88.305  -38.844 6.839   1.00 54.89  ?  7037 LEU   B H      1 
ATOM   3797 H  HA     . LEU   A  1 239 ? 88.211  -37.223 4.891   1.00 52.67  ?  7037 LEU   B HA     1 
ATOM   3798 H  HB2    . LEU   A  1 239 ? 90.384  -38.000 6.490   1.00 45.98  ?  7037 LEU   B HB2    1 
ATOM   3799 H  HB3    . LEU   A  1 239 ? 90.572  -36.890 5.369   1.00 45.98  ?  7037 LEU   B HB3    1 
ATOM   3800 H  HG     . LEU   A  1 239 ? 88.670  -36.469 7.420   1.00 55.69  ?  7037 LEU   B HG     1 
ATOM   3801 H  HD11   . LEU   A  1 239 ? 90.275  -35.338 8.612   1.00 63.95  ?  7037 LEU   B HD11   1 
ATOM   3802 H  HD12   . LEU   A  1 239 ? 90.617  -36.887 8.520   1.00 63.95  ?  7037 LEU   B HD12   1 
ATOM   3803 H  HD13   . LEU   A  1 239 ? 91.383  -35.848 7.594   1.00 63.95  ?  7037 LEU   B HD13   1 
ATOM   3804 H  HD21   . LEU   A  1 239 ? 88.962  -34.248 6.798   1.00 53.61  ?  7037 LEU   B HD21   1 
ATOM   3805 H  HD22   . LEU   A  1 239 ? 90.095  -34.669 5.768   1.00 53.61  ?  7037 LEU   B HD22   1 
ATOM   3806 H  HD23   . LEU   A  1 239 ? 88.588  -35.098 5.509   1.00 53.61  ?  7037 LEU   B HD23   1 
ATOM   3807 N  N      . SER   A  1 240 ? 89.184  -37.978 2.781   1.00 42.79  ?  7038 SER   B N      1 
ATOM   3808 C  CA     . SER   A  1 240 ? 89.746  -38.560 1.573   1.00 44.98  ?  7038 SER   B CA     1 
ATOM   3809 C  C      . SER   A  1 240 ? 90.020  -37.521 0.502   1.00 40.06  ?  7038 SER   B C      1 
ATOM   3810 O  O      . SER   A  1 240 ? 89.225  -36.604 0.277   1.00 39.91  ?  7038 SER   B O      1 
ATOM   3811 C  CB     . SER   A  1 240 ? 88.832  -39.639 0.993   1.00 43.51  ?  7038 SER   B CB     1 
ATOM   3812 O  OG     . SER   A  1 240 ? 89.403  -40.201 -0.177  1.00 44.14  ?  7038 SER   B OG     1 
ATOM   3813 H  H      . SER   A  1 240 ? 88.748  -37.244 2.676   1.00 51.87  ?  7038 SER   B H      1 
ATOM   3814 H  HA     . SER   A  1 240 ? 90.603  -38.941 1.821   1.00 54.50  ?  7038 SER   B HA     1 
ATOM   3815 H  HB2    . SER   A  1 240 ? 88.709  -40.339 1.654   1.00 52.74  ?  7038 SER   B HB2    1 
ATOM   3816 H  HB3    . SER   A  1 240 ? 87.976  -39.241 0.768   1.00 52.74  ?  7038 SER   B HB3    1 
ATOM   3817 H  HG     . SER   A  1 240 ? 88.894  -40.792 -0.490  1.00 53.49  ?  7038 SER   B HG     1 
ATOM   3818 N  N      A SER   A  1 241 ? 91.152  -37.698 -0.179  0.56 45.91  ?  7039 SER   B N      1 
ATOM   3819 N  N      B SER   A  1 241 ? 91.158  -37.688 -0.164  0.44 45.85  ?  7039 SER   B N      1 
ATOM   3820 C  CA     A SER   A  1 241 ? 91.514  -36.890 -1.332  0.56 41.21  ?  7039 SER   B CA     1 
ATOM   3821 C  CA     B SER   A  1 241 ? 91.512  -36.895 -1.328  0.44 41.25  ?  7039 SER   B CA     1 
ATOM   3822 C  C      A SER   A  1 241 ? 91.380  -37.655 -2.641  0.56 39.00  ?  7039 SER   B C      1 
ATOM   3823 C  C      B SER   A  1 241 ? 91.582  -37.743 -2.590  0.44 39.28  ?  7039 SER   B C      1 
ATOM   3824 O  O      A SER   A  1 241 ? 91.690  -37.101 -3.700  0.56 39.39  ?  7039 SER   B O      1 
ATOM   3825 O  O      B SER   A  1 241 ? 92.235  -37.347 -3.561  0.44 40.75  ?  7039 SER   B O      1 
ATOM   3826 C  CB     A SER   A  1 241 ? 92.958  -36.396 -1.200  0.56 39.97  ?  7039 SER   B CB     1 
ATOM   3827 C  CB     B SER   A  1 241 ? 92.848  -36.197 -1.084  0.44 39.87  ?  7039 SER   B CB     1 
ATOM   3828 O  OG     A SER   A  1 241 ? 93.856  -37.491 -1.094  0.56 49.62  ?  7039 SER   B OG     1 
ATOM   3829 O  OG     B SER   A  1 241 ? 92.779  -35.350 0.047   0.44 41.05  ?  7039 SER   B OG     1 
ATOM   3830 H  H      A SER   A  1 241 ? 91.738  -38.296 0.016   0.56 55.61  ?  7039 SER   B H      1 
ATOM   3831 H  H      B SER   A  1 241 ? 91.754  -38.271 0.047   0.44 55.54  ?  7039 SER   B H      1 
ATOM   3832 H  HA     A SER   A  1 241 ? 90.930  -36.117 -1.361  0.56 49.98  ?  7039 SER   B HA     1 
ATOM   3833 H  HA     B SER   A  1 241 ? 90.836  -36.214 -1.468  0.44 50.02  ?  7039 SER   B HA     1 
ATOM   3834 H  HB2    A SER   A  1 241 ? 93.187  -35.874 -1.985  0.56 48.48  ?  7039 SER   B HB2    1 
ATOM   3835 H  HB2    B SER   A  1 241 ? 93.532  -36.869 -0.934  0.44 48.37  ?  7039 SER   B HB2    1 
ATOM   3836 H  HB3    A SER   A  1 241 ? 93.033  -35.847 -0.403  0.56 48.48  ?  7039 SER   B HB3    1 
ATOM   3837 H  HB3    B SER   A  1 241 ? 93.073  -35.665 -1.863  0.44 48.37  ?  7039 SER   B HB3    1 
ATOM   3838 H  HG     A SER   A  1 241 ? 94.640  -37.210 -0.984  0.56 60.07  ?  7039 SER   B HG     1 
ATOM   3839 H  HG     B SER   A  1 241 ? 93.502  -34.933 0.138   0.44 49.78  ?  7039 SER   B HG     1 
ATOM   3840 N  N      . TYR   A  1 242 ? 90.927  -38.912 -2.591  1.00 41.85  ?  7040 TYR   B N      1 
ATOM   3841 C  CA     . TYR   A  1 242 ? 91.066  -39.824 -3.724  1.00 42.06  ?  7040 TYR   B CA     1 
ATOM   3842 C  C      . TYR   A  1 242 ? 90.475  -39.226 -5.004  1.00 41.36  ?  7040 TYR   B C      1 
ATOM   3843 O  O      . TYR   A  1 242 ? 91.093  -39.315 -6.075  1.00 44.06  ?  7040 TYR   B O      1 
ATOM   3844 C  CB     . TYR   A  1 242 ? 90.381  -41.160 -3.401  1.00 49.28  ?  7040 TYR   B CB     1 
ATOM   3845 C  CG     . TYR   A  1 242 ? 91.010  -41.984 -2.292  1.00 57.91  ?  7040 TYR   B CG     1 
ATOM   3846 C  CD1    . TYR   A  1 242 ? 92.177  -41.587 -1.675  1.00 53.47  ?  7040 TYR   B CD1    1 
ATOM   3847 C  CD2    . TYR   A  1 242 ? 90.410  -43.149 -1.855  1.00 52.72  ?  7040 TYR   B CD2    1 
ATOM   3848 C  CE1    . TYR   A  1 242 ? 92.743  -42.329 -0.656  1.00 55.67  ?  7040 TYR   B CE1    1 
ATOM   3849 C  CE2    . TYR   A  1 242 ? 90.973  -43.905 -0.818  1.00 47.99  ?  7040 TYR   B CE2    1 
ATOM   3850 C  CZ     . TYR   A  1 242 ? 92.144  -43.487 -0.220  1.00 43.39  ?  7040 TYR   B CZ     1 
ATOM   3851 O  OH     . TYR   A  1 242 ? 92.712  -44.221 0.803   1.00 54.05  ?  7040 TYR   B OH     1 
ATOM   3852 H  H      A TYR   A  1 242 ? 90.534  -39.260 -1.910  0.56 50.74  ?  7040 TYR   B H      1 
ATOM   3853 H  H      B TYR   A  1 242 ? 90.409  -39.190 -1.963  0.44 50.74  ?  7040 TYR   B H      1 
ATOM   3854 H  HA     . TYR   A  1 242 ? 92.010  -39.986 -3.875  1.00 50.99  ?  7040 TYR   B HA     1 
ATOM   3855 H  HB2    . TYR   A  1 242 ? 89.466  -40.975 -3.136  1.00 59.66  ?  7040 TYR   B HB2    1 
ATOM   3856 H  HB3    . TYR   A  1 242 ? 90.390  -41.706 -4.203  1.00 59.66  ?  7040 TYR   B HB3    1 
ATOM   3857 H  HD1    . TYR   A  1 242 ? 92.593  -40.802 -1.951  1.00 64.69  ?  7040 TYR   B HD1    1 
ATOM   3858 H  HD2    . TYR   A  1 242 ? 89.622  -43.436 -2.255  1.00 63.78  ?  7040 TYR   B HD2    1 
ATOM   3859 H  HE1    . TYR   A  1 242 ? 93.536  -42.043 -0.262  1.00 67.33  ?  7040 TYR   B HE1    1 
ATOM   3860 H  HE2    . TYR   A  1 242 ? 90.558  -44.687 -0.533  1.00 58.11  ?  7040 TYR   B HE2    1 
ATOM   3861 H  HH     . TYR   A  1 242 ? 92.282  -44.933 0.918   1.00 65.38  ?  7040 TYR   B HH     1 
ATOM   3862 N  N      . SER   A  1 243 ? 89.296  -38.597 -4.925  1.00 38.74  ?  7041 SER   B N      1 
ATOM   3863 C  CA     . SER   A  1 243 ? 88.623  -38.157 -6.144  1.00 37.94  ?  7041 SER   B CA     1 
ATOM   3864 C  C      . SER   A  1 243 ? 89.383  -37.041 -6.853  1.00 41.86  ?  7041 SER   B C      1 
ATOM   3865 O  O      . SER   A  1 243 ? 89.137  -36.790 -8.038  1.00 40.21  ?  7041 SER   B O      1 
ATOM   3866 C  CB     . SER   A  1 243 ? 87.188  -37.707 -5.831  1.00 37.78  ?  7041 SER   B CB     1 
ATOM   3867 O  OG     . SER   A  1 243 ? 87.128  -36.446 -5.171  1.00 41.23  ?  7041 SER   B OG     1 
ATOM   3868 H  H      . SER   A  1 243 ? 88.878  -38.421 -4.195  1.00 47.01  ?  7041 SER   B H      1 
ATOM   3869 H  HA     . SER   A  1 243 ? 88.566  -38.908 -6.754  1.00 46.05  ?  7041 SER   B HA     1 
ATOM   3870 H  HB2    . SER   A  1 243 ? 86.699  -37.639 -6.666  1.00 45.86  ?  7041 SER   B HB2    1 
ATOM   3871 H  HB3    . SER   A  1 243 ? 86.777  -38.372 -5.258  1.00 45.86  ?  7041 SER   B HB3    1 
ATOM   3872 H  HG     . SER   A  1 243 ? 87.394  -35.838 -5.687  1.00 50.00  ?  7041 SER   B HG     1 
ATOM   3873 N  N      . LEU   A  1 244 ? 90.325  -36.384 -6.169  1.00 45.87  ?  7042 LEU   B N      1 
ATOM   3874 C  CA     . LEU   A  1 244 ? 91.061  -35.289 -6.802  1.00 45.91  ?  7042 LEU   B CA     1 
ATOM   3875 C  C      . LEU   A  1 244 ? 91.990  -35.787 -7.907  1.00 44.94  ?  7042 LEU   B C      1 
ATOM   3876 O  O      . LEU   A  1 244 ? 92.350  -35.019 -8.806  1.00 40.95  ?  7042 LEU   B O      1 
ATOM   3877 C  CB     . LEU   A  1 244 ? 91.872  -34.527 -5.758  1.00 40.65  ?  7042 LEU   B CB     1 
ATOM   3878 C  CG     . LEU   A  1 244 ? 91.057  -34.030 -4.563  1.00 42.73  ?  7042 LEU   B CG     1 
ATOM   3879 C  CD1    . LEU   A  1 244 ? 91.998  -33.419 -3.553  1.00 38.97  ?  7042 LEU   B CD1    1 
ATOM   3880 C  CD2    . LEU   A  1 244 ? 89.989  -33.059 -4.976  1.00 43.24  ?  7042 LEU   B CD2    1 
ATOM   3881 H  H      . LEU   A  1 244 ? 90.551  -36.549 -5.355  1.00 55.57  ?  7042 LEU   B H      1 
ATOM   3882 H  HA     . LEU   A  1 244 ? 90.423  -34.674 -7.196  1.00 55.62  ?  7042 LEU   B HA     1 
ATOM   3883 H  HB2    . LEU   A  1 244 ? 92.564  -35.114 -5.417  1.00 49.30  ?  7042 LEU   B HB2    1 
ATOM   3884 H  HB3    . LEU   A  1 244 ? 92.272  -33.753 -6.183  1.00 49.30  ?  7042 LEU   B HB3    1 
ATOM   3885 H  HG     . LEU   A  1 244 ? 90.592  -34.776 -4.155  1.00 51.80  ?  7042 LEU   B HG     1 
ATOM   3886 H  HD11   . LEU   A  1 244 ? 91.508  -33.235 -2.736  1.00 47.28  ?  7042 LEU   B HD11   1 
ATOM   3887 H  HD12   . LEU   A  1 244 ? 92.718  -34.043 -3.375  1.00 47.28  ?  7042 LEU   B HD12   1 
ATOM   3888 H  HD13   . LEU   A  1 244 ? 92.357  -32.594 -3.916  1.00 47.28  ?  7042 LEU   B HD13   1 
ATOM   3889 H  HD21   . LEU   A  1 244 ? 89.500  -32.773 -4.188  1.00 52.41  ?  7042 LEU   B HD21   1 
ATOM   3890 H  HD22   . LEU   A  1 244 ? 90.405  -32.294 -5.403  1.00 52.41  ?  7042 LEU   B HD22   1 
ATOM   3891 H  HD23   . LEU   A  1 244 ? 89.387  -33.497 -5.598  1.00 52.41  ?  7042 LEU   B HD23   1 
ATOM   3892 N  N      . PHE   A  1 245 ? 92.402  -37.050 -7.837  1.00 41.12  ?  7043 PHE   B N      1 
ATOM   3893 C  CA     . PHE   A  1 245 ? 93.321  -37.633 -8.793  1.00 43.72  ?  7043 PHE   B CA     1 
ATOM   3894 C  C      . PHE   A  1 245 ? 92.635  -38.084 -10.076 1.00 46.03  ?  7043 PHE   B C      1 
ATOM   3895 O  O      . PHE   A  1 245 ? 93.333  -38.499 -11.007 1.00 59.20  ?  7043 PHE   B O      1 
ATOM   3896 C  CB     . PHE   A  1 245 ? 94.047  -38.799 -8.137  1.00 46.13  ?  7043 PHE   B CB     1 
ATOM   3897 C  CG     . PHE   A  1 245 ? 95.016  -38.382 -7.090  1.00 45.25  ?  7043 PHE   B CG     1 
ATOM   3898 C  CD1    . PHE   A  1 245 ? 96.307  -38.095 -7.438  1.00 43.60  ?  7043 PHE   B CD1    1 
ATOM   3899 C  CD2    . PHE   A  1 245 ? 94.623  -38.216 -5.777  1.00 43.05  ?  7043 PHE   B CD2    1 
ATOM   3900 C  CE1    . PHE   A  1 245 ? 97.212  -37.695 -6.488  1.00 44.88  ?  7043 PHE   B CE1    1 
ATOM   3901 C  CE2    . PHE   A  1 245 ? 95.514  -37.816 -4.825  1.00 48.10  ?  7043 PHE   B CE2    1 
ATOM   3902 C  CZ     . PHE   A  1 245 ? 96.811  -37.553 -5.173  1.00 45.09  ?  7043 PHE   B CZ     1 
ATOM   3903 H  H      . PHE   A  1 245 ? 92.152  -37.602 -7.227  1.00 49.87  ?  7043 PHE   B H      1 
ATOM   3904 H  HA     . PHE   A  1 245 ? 93.985  -36.973 -9.047  1.00 52.98  ?  7043 PHE   B HA     1 
ATOM   3905 H  HB2    . PHE   A  1 245 ? 93.392  -39.381 -7.721  1.00 55.88  ?  7043 PHE   B HB2    1 
ATOM   3906 H  HB3    . PHE   A  1 245 ? 94.538  -39.285 -8.819  1.00 55.88  ?  7043 PHE   B HB3    1 
ATOM   3907 H  HD1    . PHE   A  1 245 ? 96.574  -38.172 -8.326  1.00 52.84  ?  7043 PHE   B HD1    1 
ATOM   3908 H  HD2    . PHE   A  1 245 ? 93.739  -38.380 -5.539  1.00 52.18  ?  7043 PHE   B HD2    1 
ATOM   3909 H  HE1    . PHE   A  1 245 ? 98.093  -37.520 -6.728  1.00 54.38  ?  7043 PHE   B HE1    1 
ATOM   3910 H  HE2    . PHE   A  1 245 ? 95.241  -37.722 -3.941  1.00 58.24  ?  7043 PHE   B HE2    1 
ATOM   3911 H  HZ     . PHE   A  1 245 ? 97.421  -37.279 -4.527  1.00 54.63  ?  7043 PHE   B HZ     1 
ATOM   3912 N  N      . ASP   A  1 246 ? 91.306  -38.033 -10.162 1.00 45.13  ?  7044 ASP   B N      1 
ATOM   3913 C  CA     . ASP   A  1 246 ? 90.605  -38.348 -11.409 1.00 49.94  ?  7044 ASP   B CA     1 
ATOM   3914 C  C      . ASP   A  1 246 ? 89.761  -37.169 -11.878 1.00 41.64  ?  7044 ASP   B C      1 
ATOM   3915 O  O      . ASP   A  1 246 ? 88.650  -36.949 -11.385 1.00 44.94  ?  7044 ASP   B O      1 
ATOM   3916 C  CB     . ASP   A  1 246 ? 89.720  -39.588 -11.242 1.00 59.03  ?  7044 ASP   B CB     1 
ATOM   3917 C  CG     . ASP   A  1 246 ? 89.202  -40.110 -12.559 1.00 61.71  ?  7044 ASP   B CG     1 
ATOM   3918 O  OD1    . ASP   A  1 246 ? 89.657  -39.670 -13.623 1.00 48.15  ?  7044 ASP   B OD1    1 
ATOM   3919 O  OD2    . ASP   A  1 246 ? 88.290  -40.935 -12.555 1.00 65.31  ?  7044 ASP   B OD2    1 
ATOM   3920 H  H      . ASP   A  1 246 ? 90.787  -37.818 -9.511  1.00 54.68  ?  7044 ASP   B H      1 
ATOM   3921 H  HA     . ASP   A  1 246 ? 91.286  -38.501 -12.083 1.00 60.46  ?  7044 ASP   B HA     1 
ATOM   3922 H  HB2    . ASP   A  1 246 ? 90.238  -40.292 -10.821 1.00 71.36  ?  7044 ASP   B HB2    1 
ATOM   3923 H  HB3    . ASP   A  1 246 ? 88.958  -39.360 -10.687 1.00 71.36  ?  7044 ASP   B HB3    1 
ATOM   3924 N  N      . MET   A  1 247 ? 90.259  -36.446 -12.873 1.00 42.53  ?  7045 MET   B N      1 
ATOM   3925 C  CA     . MET   A  1 247 ? 89.607  -35.239 -13.356 1.00 45.40  ?  7045 MET   B CA     1 
ATOM   3926 C  C      . MET   A  1 247 ? 89.128  -35.377 -14.794 1.00 40.29  ?  7045 MET   B C      1 
ATOM   3927 O  O      . MET   A  1 247 ? 88.718  -34.379 -15.394 1.00 43.92  ?  7045 MET   B O      1 
ATOM   3928 C  CB     . MET   A  1 247 ? 90.579  -34.067 -13.228 1.00 43.89  ?  7045 MET   B CB     1 
ATOM   3929 C  CG     . MET   A  1 247 ? 91.053  -33.842 -11.806 1.00 45.04  ?  7045 MET   B CG     1 
ATOM   3930 S  SD     . MET   A  1 247 ? 89.723  -33.087 -10.832 1.00 45.09  ?  7045 MET   B SD     1 
ATOM   3931 C  CE     . MET   A  1 247 ? 89.633  -31.484 -11.627 1.00 36.12  ?  7045 MET   B CE     1 
ATOM   3932 H  H      . MET   A  1 247 ? 90.986  -36.639 -13.291 1.00 51.56  ?  7045 MET   B H      1 
ATOM   3933 H  HA     . MET   A  1 247 ? 88.830  -35.051 -12.806 1.00 55.00  ?  7045 MET   B HA     1 
ATOM   3934 H  HB2    . MET   A  1 247 ? 91.358  -34.243 -13.779 1.00 53.19  ?  7045 MET   B HB2    1 
ATOM   3935 H  HB3    . MET   A  1 247 ? 90.137  -33.257 -13.528 1.00 53.19  ?  7045 MET   B HB3    1 
ATOM   3936 H  HG2    . MET   A  1 247 ? 91.293  -34.691 -11.402 1.00 54.56  ?  7045 MET   B HG2    1 
ATOM   3937 H  HG3    . MET   A  1 247 ? 91.818  -33.246 -11.805 1.00 54.56  ?  7045 MET   B HG3    1 
ATOM   3938 H  HE1    . MET   A  1 247 ? 89.141  -30.875 -11.055 1.00 43.87  ?  7045 MET   B HE1    1 
ATOM   3939 H  HE2    . MET   A  1 247 ? 90.533  -31.151 -11.769 1.00 43.87  ?  7045 MET   B HE2    1 
ATOM   3940 H  HE3    . MET   A  1 247 ? 89.178  -31.579 -12.479 1.00 43.87  ?  7045 MET   B HE3    1 
ATOM   3941 N  N      . SER   A  1 248 ? 89.149  -36.589 -15.350 1.00 45.17  ?  7046 SER   B N      1 
ATOM   3942 C  CA     . SER   A  1 248 ? 88.825  -36.782 -16.764 1.00 46.36  ?  7046 SER   B CA     1 
ATOM   3943 C  C      . SER   A  1 248 ? 87.397  -36.365 -17.093 1.00 47.77  ?  7046 SER   B C      1 
ATOM   3944 O  O      . SER   A  1 248 ? 87.141  -35.873 -18.197 1.00 50.70  ?  7046 SER   B O      1 
ATOM   3945 C  CB     . SER   A  1 248 ? 89.044  -38.246 -17.140 1.00 45.98  ?  7046 SER   B CB     1 
ATOM   3946 O  OG     . SER   A  1 248 ? 88.330  -39.085 -16.242 1.00 59.65  ?  7046 SER   B OG     1 
ATOM   3947 H  H      . SER   A  1 248 ? 89.347  -37.315 -14.933 1.00 54.72  ?  7046 SER   B H      1 
ATOM   3948 H  HA     . SER   A  1 248 ? 89.419  -36.228 -17.295 1.00 56.15  ?  7046 SER   B HA     1 
ATOM   3949 H  HB2    . SER   A  1 248 ? 88.722  -38.396 -18.043 1.00 55.70  ?  7046 SER   B HB2    1 
ATOM   3950 H  HB3    . SER   A  1 248 ? 89.990  -38.452 -17.087 1.00 55.70  ?  7046 SER   B HB3    1 
ATOM   3951 H  HG     . SER   A  1 248 ? 88.697  -39.076 -15.487 1.00 72.10  ?  7046 SER   B HG     1 
ATOM   3952 N  N      . LYS   A  1 249 ? 86.455  -36.574 -16.172 1.00 51.89  ?  7047 LYS   B N      1 
ATOM   3953 C  CA     . LYS   A  1 249 ? 85.055  -36.240 -16.401 1.00 50.56  ?  7047 LYS   B CA     1 
ATOM   3954 C  C      . LYS   A  1 249 ? 84.634  -35.005 -15.622 1.00 43.50  ?  7047 LYS   B C      1 
ATOM   3955 O  O      . LYS   A  1 249 ? 83.447  -34.828 -15.319 1.00 50.03  ?  7047 LYS   B O      1 
ATOM   3956 C  CB     . LYS   A  1 249 ? 84.148  -37.416 -16.029 1.00 56.90  ?  7047 LYS   B CB     1 
ATOM   3957 C  CG     . LYS   A  1 249 ? 84.643  -38.779 -16.509 1.00 59.38  ?  7047 LYS   B CG     1 
ATOM   3958 C  CD     . LYS   A  1 249 ? 84.137  -39.128 -17.899 1.00 75.98  ?  7047 LYS   B CD     1 
ATOM   3959 C  CE     . LYS   A  1 249 ? 84.630  -40.486 -18.331 1.00 87.09  ?  7047 LYS   B CE     1 
ATOM   3960 N  NZ     . LYS   A  1 249 ? 85.686  -40.414 -19.372 1.00 93.65  ?  7047 LYS   B NZ     1 
ATOM   3961 H  H      . LYS   A  1 249 ? 86.607  -36.913 -15.396 1.00 62.78  ?  7047 LYS   B H      1 
ATOM   3962 H  HA     . LYS   A  1 249 ? 84.940  -36.062 -17.347 1.00 61.20  ?  7047 LYS   B HA     1 
ATOM   3963 H  HB2    . LYS   A  1 249 ? 84.074  -37.455 -15.062 1.00 68.80  ?  7047 LYS   B HB2    1 
ATOM   3964 H  HB3    . LYS   A  1 249 ? 83.273  -37.267 -16.422 1.00 68.80  ?  7047 LYS   B HB3    1 
ATOM   3965 H  HG2    . LYS   A  1 249 ? 85.613  -38.773 -16.536 1.00 71.77  ?  7047 LYS   B HG2    1 
ATOM   3966 H  HG3    . LYS   A  1 249 ? 84.333  -39.463 -15.896 1.00 71.77  ?  7047 LYS   B HG3    1 
ATOM   3967 H  HD2    . LYS   A  1 249 ? 83.167  -39.141 -17.895 1.00 91.70  ?  7047 LYS   B HD2    1 
ATOM   3968 H  HD3    . LYS   A  1 249 ? 84.458  -38.469 -18.534 1.00 91.70  ?  7047 LYS   B HD3    1 
ATOM   3969 H  HE2    . LYS   A  1 249 ? 85.000  -40.947 -17.562 1.00 105.03 ?  7047 LYS   B HE2    1 
ATOM   3970 H  HE3    . LYS   A  1 249 ? 83.886  -40.991 -18.695 1.00 105.03 ?  7047 LYS   B HE3    1 
ATOM   3971 H  HZ1    . LYS   A  1 249 ? 85.941  -41.234 -19.604 1.00 112.90 ?  7047 LYS   B HZ1    1 
ATOM   3972 H  HZ2    . LYS   A  1 249 ? 85.374  -39.994 -20.093 1.00 112.90 ?  7047 LYS   B HZ2    1 
ATOM   3973 H  HZ3    . LYS   A  1 249 ? 86.390  -39.968 -19.061 1.00 112.90 ?  7047 LYS   B HZ3    1 
ATOM   3974 N  N      . PHE   A  1 250 ? 85.588  -34.155 -15.288 1.00 47.09  ?  7048 PHE   B N      1 
ATOM   3975 C  CA     . PHE   A  1 250 ? 85.292  -33.009 -14.433 1.00 46.97  ?  7048 PHE   B CA     1 
ATOM   3976 C  C      . PHE   A  1 250 ? 84.423  -31.960 -15.103 1.00 38.72  ?  7048 PHE   B C      1 
ATOM   3977 O  O      . PHE   A  1 250 ? 83.456  -31.498 -14.477 1.00 40.23  ?  7048 PHE   B O      1 
ATOM   3978 C  CB     . PHE   A  1 250 ? 86.607  -32.399 -13.943 1.00 45.58  ?  7048 PHE   B CB     1 
ATOM   3979 C  CG     . PHE   A  1 250 ? 86.423  -31.265 -12.994 1.00 40.14  ?  7048 PHE   B CG     1 
ATOM   3980 C  CD1    . PHE   A  1 250 ? 85.929  -31.480 -11.725 1.00 42.91  ?  7048 PHE   B CD1    1 
ATOM   3981 C  CD2    . PHE   A  1 250 ? 86.738  -29.968 -13.390 1.00 37.17  ?  7048 PHE   B CD2    1 
ATOM   3982 C  CE1    . PHE   A  1 250 ? 85.754  -30.444 -10.860 1.00 42.40  ?  7048 PHE   B CE1    1 
ATOM   3983 C  CE2    . PHE   A  1 250 ? 86.555  -28.913 -12.539 1.00 40.96  ?  7048 PHE   B CE2    1 
ATOM   3984 C  CZ     . PHE   A  1 250 ? 86.060  -29.152 -11.261 1.00 40.79  ?  7048 PHE   B CZ     1 
ATOM   3985 H  H      . PHE   A  1 250 ? 86.409  -34.212 -15.537 1.00 57.03  ?  7048 PHE   B H      1 
ATOM   3986 H  HA     . PHE   A  1 250 ? 84.788  -33.347 -13.675 1.00 56.89  ?  7048 PHE   B HA     1 
ATOM   3987 H  HB2    . PHE   A  1 250 ? 87.119  -33.086 -13.489 1.00 55.21  ?  7048 PHE   B HB2    1 
ATOM   3988 H  HB3    . PHE   A  1 250 ? 87.101  -32.068 -14.709 1.00 55.21  ?  7048 PHE   B HB3    1 
ATOM   3989 H  HD1    . PHE   A  1 250 ? 85.713  -32.344 -11.456 1.00 52.02  ?  7048 PHE   B HD1    1 
ATOM   3990 H  HD2    . PHE   A  1 250 ? 87.078  -29.817 -14.243 1.00 45.13  ?  7048 PHE   B HD2    1 
ATOM   3991 H  HE1    . PHE   A  1 250 ? 85.430  -30.601 -10.003 1.00 51.41  ?  7048 PHE   B HE1    1 
ATOM   3992 H  HE2    . PHE   A  1 250 ? 86.758  -28.047 -12.812 1.00 49.67  ?  7048 PHE   B HE2    1 
ATOM   3993 H  HZ     . PHE   A  1 250 ? 85.934  -28.442 -10.674 1.00 49.47  ?  7048 PHE   B HZ     1 
ATOM   3994 N  N      . PRO   A  1 251 ? 84.700  -31.520 -16.327 1.00 43.04  ?  7049 PRO   B N      1 
ATOM   3995 C  CA     . PRO   A  1 251 ? 83.952  -30.378 -16.870 1.00 45.70  ?  7049 PRO   B CA     1 
ATOM   3996 C  C      . PRO   A  1 251 ? 82.458  -30.620 -16.928 1.00 41.01  ?  7049 PRO   B C      1 
ATOM   3997 O  O      . PRO   A  1 251 ? 81.989  -31.702 -17.290 1.00 49.39  ?  7049 PRO   B O      1 
ATOM   3998 C  CB     . PRO   A  1 251 ? 84.552  -30.150 -18.264 1.00 44.81  ?  7049 PRO   B CB     1 
ATOM   3999 C  CG     . PRO   A  1 251 ? 85.571  -31.243 -18.508 1.00 42.80  ?  7049 PRO   B CG     1 
ATOM   4000 C  CD     . PRO   A  1 251 ? 85.606  -32.167 -17.302 1.00 38.72  ?  7049 PRO   B CD     1 
ATOM   4001 H  HA     . PRO   A  1 251 ? 84.122  -29.600 -16.316 1.00 55.36  ?  7049 PRO   B HA     1 
ATOM   4002 H  HB2    . PRO   A  1 251 ? 83.845  -30.193 -18.927 1.00 54.29  ?  7049 PRO   B HB2    1 
ATOM   4003 H  HB3    . PRO   A  1 251 ? 84.978  -29.279 -18.290 1.00 54.29  ?  7049 PRO   B HB3    1 
ATOM   4004 H  HG2    . PRO   A  1 251 ? 85.314  -31.741 -19.300 1.00 51.88  ?  7049 PRO   B HG2    1 
ATOM   4005 H  HG3    . PRO   A  1 251 ? 86.442  -30.836 -18.639 1.00 51.88  ?  7049 PRO   B HG3    1 
ATOM   4006 H  HD2    . PRO   A  1 251 ? 85.281  -33.050 -17.538 1.00 46.99  ?  7049 PRO   B HD2    1 
ATOM   4007 H  HD3    . PRO   A  1 251 ? 86.505  -32.229 -16.944 1.00 46.99  ?  7049 PRO   B HD3    1 
ATOM   4008 N  N      . LEU   A  1 252 ? 81.712  -29.581 -16.567 1.00 42.46  ?  7050 LEU   B N      1 
ATOM   4009 C  CA     . LEU   A  1 252 ? 80.258  -29.614 -16.608 1.00 44.26  ?  7050 LEU   B CA     1 
ATOM   4010 C  C      . LEU   A  1 252 ? 79.804  -29.755 -18.057 1.00 46.10  ?  7050 LEU   B C      1 
ATOM   4011 O  O      . LEU   A  1 252 ? 80.148  -28.927 -18.908 1.00 45.31  ?  7050 LEU   B O      1 
ATOM   4012 C  CB     . LEU   A  1 252 ? 79.708  -28.337 -15.977 1.00 41.61  ?  7050 LEU   B CB     1 
ATOM   4013 C  CG     . LEU   A  1 252 ? 78.199  -28.160 -15.899 1.00 39.95  ?  7050 LEU   B CG     1 
ATOM   4014 C  CD1    . LEU   A  1 252 ? 77.576  -29.330 -15.185 1.00 47.67  ?  7050 LEU   B CD1    1 
ATOM   4015 C  CD2    . LEU   A  1 252 ? 77.852  -26.869 -15.201 1.00 43.14  ?  7050 LEU   B CD2    1 
ATOM   4016 H  H      . LEU   A  1 252 ? 82.031  -28.832 -16.289 1.00 51.47  ?  7050 LEU   B H      1 
ATOM   4017 H  HA     . LEU   A  1 252 ? 79.917  -30.371 -16.108 1.00 53.64  ?  7050 LEU   B HA     1 
ATOM   4018 H  HB2    . LEU   A  1 252 ? 80.039  -28.294 -15.066 1.00 50.45  ?  7050 LEU   B HB2    1 
ATOM   4019 H  HB3    . LEU   A  1 252 ? 80.048  -27.587 -16.490 1.00 50.45  ?  7050 LEU   B HB3    1 
ATOM   4020 H  HG     . LEU   A  1 252 ? 77.835  -28.122 -16.797 1.00 48.46  ?  7050 LEU   B HG     1 
ATOM   4021 H  HD11   . LEU   A  1 252 ? 76.636  -29.145 -15.036 1.00 57.73  ?  7050 LEU   B HD11   1 
ATOM   4022 H  HD12   . LEU   A  1 252 ? 77.674  -30.124 -15.734 1.00 57.73  ?  7050 LEU   B HD12   1 
ATOM   4023 H  HD13   . LEU   A  1 252 ? 78.026  -29.458 -14.335 1.00 57.73  ?  7050 LEU   B HD13   1 
ATOM   4024 H  HD21   . LEU   A  1 252 ? 76.887  -26.767 -15.186 1.00 52.29  ?  7050 LEU   B HD21   1 
ATOM   4025 H  HD22   . LEU   A  1 252 ? 78.195  -26.897 -14.294 1.00 52.29  ?  7050 LEU   B HD22   1 
ATOM   4026 H  HD23   . LEU   A  1 252 ? 78.255  -26.130 -15.684 1.00 52.29  ?  7050 LEU   B HD23   1 
ATOM   4027 N  N      A LYS   A  1 253 ? 79.056  -30.821 -18.349 0.48 56.23  ?  7051 LYS   B N      1 
ATOM   4028 N  N      B LYS   A  1 253 ? 79.035  -30.801 -18.327 0.52 56.24  ?  7051 LYS   B N      1 
ATOM   4029 C  CA     A LYS   A  1 253 ? 78.602  -31.059 -19.717 0.48 56.95  ?  7051 LYS   B CA     1 
ATOM   4030 C  CA     B LYS   A  1 253 ? 78.517  -31.054 -19.665 0.52 56.95  ?  7051 LYS   B CA     1 
ATOM   4031 C  C      A LYS   A  1 253 ? 77.675  -29.921 -20.134 0.48 50.05  ?  7051 LYS   B C      1 
ATOM   4032 C  C      B LYS   A  1 253 ? 77.652  -29.880 -20.111 0.52 50.04  ?  7051 LYS   B C      1 
ATOM   4033 O  O      A LYS   A  1 253 ? 76.670  -29.654 -19.467 0.48 53.29  ?  7051 LYS   B O      1 
ATOM   4034 O  O      B LYS   A  1 253 ? 76.674  -29.539 -19.440 0.52 53.28  ?  7051 LYS   B O      1 
ATOM   4035 C  CB     A LYS   A  1 253 ? 77.892  -32.412 -19.823 0.48 62.98  ?  7051 LYS   B CB     1 
ATOM   4036 C  CB     B LYS   A  1 253 ? 77.719  -32.362 -19.636 0.52 62.97  ?  7051 LYS   B CB     1 
ATOM   4037 C  CG     A LYS   A  1 253 ? 77.985  -33.061 -21.196 0.48 67.44  ?  7051 LYS   B CG     1 
ATOM   4038 C  CG     B LYS   A  1 253 ? 78.540  -33.512 -19.046 0.52 66.36  ?  7051 LYS   B CG     1 
ATOM   4039 C  CD     A LYS   A  1 253 ? 76.867  -32.645 -22.134 0.48 62.47  ?  7051 LYS   B CD     1 
ATOM   4040 C  CD     B LYS   A  1 253 ? 77.754  -34.802 -18.843 0.52 68.53  ?  7051 LYS   B CD     1 
ATOM   4041 C  CE     A LYS   A  1 253 ? 76.904  -33.445 -23.446 0.48 52.61  ?  7051 LYS   B CE     1 
ATOM   4042 C  CE     B LYS   A  1 253 ? 78.678  -35.913 -18.341 0.52 70.50  ?  7051 LYS   B CE     1 
ATOM   4043 N  NZ     A LYS   A  1 253 ? 75.871  -32.977 -24.422 0.48 54.40  ?  7051 LYS   B NZ     1 
ATOM   4044 N  NZ     B LYS   A  1 253 ? 79.937  -35.997 -19.125 0.52 66.71  ?  7051 LYS   B NZ     1 
ATOM   4045 H  H      A LYS   A  1 253 ? 78.802  -31.413 -17.779 0.48 68.00  ?  7051 LYS   B H      1 
ATOM   4046 H  H      B LYS   A  1 253 ? 78.794  -31.388 -17.746 0.52 68.01  ?  7051 LYS   B H      1 
ATOM   4047 H  HA     A LYS   A  1 253 ? 79.364  -31.085 -20.317 0.48 68.86  ?  7051 LYS   B HA     1 
ATOM   4048 H  HA     B LYS   A  1 253 ? 79.238  -31.148 -20.307 0.52 68.86  ?  7051 LYS   B HA     1 
ATOM   4049 H  HB2    A LYS   A  1 253 ? 78.290  -33.022 -19.182 0.48 76.10  ?  7051 LYS   B HB2    1 
ATOM   4050 H  HB2    B LYS   A  1 253 ? 76.927  -32.242 -19.089 0.52 76.08  ?  7051 LYS   B HB2    1 
ATOM   4051 H  HB3    A LYS   A  1 253 ? 76.952  -32.285 -19.620 0.48 76.10  ?  7051 LYS   B HB3    1 
ATOM   4052 H  HB3    B LYS   A  1 253 ? 77.465  -32.602 -20.541 0.52 76.08  ?  7051 LYS   B HB3    1 
ATOM   4053 H  HG2    A LYS   A  1 253 ? 78.827  -32.808 -21.607 0.48 81.45  ?  7051 LYS   B HG2    1 
ATOM   4054 H  HG2    B LYS   A  1 253 ? 79.276  -33.708 -19.647 0.52 80.15  ?  7051 LYS   B HG2    1 
ATOM   4055 H  HG3    A LYS   A  1 253 ? 77.943  -34.024 -21.092 0.48 81.45  ?  7051 LYS   B HG3    1 
ATOM   4056 H  HG3    B LYS   A  1 253 ? 78.882  -33.237 -18.181 0.52 80.15  ?  7051 LYS   B HG3    1 
ATOM   4057 H  HD2    A LYS   A  1 253 ? 76.012  -32.803 -21.705 0.48 75.49  ?  7051 LYS   B HD2    1 
ATOM   4058 H  HD2    B LYS   A  1 253 ? 77.056  -34.659 -18.185 0.52 82.76  ?  7051 LYS   B HD2    1 
ATOM   4059 H  HD3    A LYS   A  1 253 ? 76.961  -31.704 -22.349 0.48 75.49  ?  7051 LYS   B HD3    1 
ATOM   4060 H  HD3    B LYS   A  1 253 ? 77.363  -35.082 -19.686 0.52 82.76  ?  7051 LYS   B HD3    1 
ATOM   4061 H  HE2    A LYS   A  1 253 ? 77.777  -33.343 -23.857 0.48 63.66  ?  7051 LYS   B HE2    1 
ATOM   4062 H  HE2    B LYS   A  1 253 ? 78.911  -35.739 -17.415 0.52 85.12  ?  7051 LYS   B HE2    1 
ATOM   4063 H  HE3    A LYS   A  1 253 ? 76.736  -34.381 -23.253 0.48 63.66  ?  7051 LYS   B HE3    1 
ATOM   4064 H  HE3    B LYS   A  1 253 ? 78.221  -36.765 -18.413 0.52 85.12  ?  7051 LYS   B HE3    1 
ATOM   4065 H  HZ1    A LYS   A  1 253 ? 75.917  -33.459 -25.169 0.48 65.80  ?  7051 LYS   B HZ1    1 
ATOM   4066 H  HZ1    B LYS   A  1 253 ? 79.752  -36.006 -19.995 0.52 80.57  ?  7051 LYS   B HZ1    1 
ATOM   4067 H  HZ2    A LYS   A  1 253 ? 75.058  -33.065 -24.071 0.48 65.80  ?  7051 LYS   B HZ2    1 
ATOM   4068 H  HZ2    B LYS   A  1 253 ? 80.453  -35.294 -18.947 0.52 80.57  ?  7051 LYS   B HZ2    1 
ATOM   4069 H  HZ3    A LYS   A  1 253 ? 76.007  -32.121 -24.622 0.48 65.80  ?  7051 LYS   B HZ3    1 
ATOM   4070 H  HZ3    B LYS   A  1 253 ? 80.377  -36.741 -18.914 0.52 80.57  ?  7051 LYS   B HZ3    1 
ATOM   4071 N  N      . LEU   A  1 254 ? 78.026  -29.227 -21.215 1.00 52.98  ?  7052 LEU   B N      1 
ATOM   4072 C  CA     . LEU   A  1 254 ? 77.187  -28.154 -21.741 1.00 51.07  ?  7052 LEU   B CA     1 
ATOM   4073 C  C      . LEU   A  1 254 ? 75.983  -28.851 -22.372 1.00 56.80  ?  7052 LEU   B C      1 
ATOM   4074 O  O      . LEU   A  1 254 ? 76.117  -29.560 -23.377 1.00 62.94  ?  7052 LEU   B O      1 
ATOM   4075 C  CB     . LEU   A  1 254 ? 77.955  -27.280 -22.732 1.00 58.38  ?  7052 LEU   B CB     1 
ATOM   4076 C  CG     . LEU   A  1 254 ? 77.184  -26.134 -23.404 1.00 70.08  ?  7052 LEU   B CG     1 
ATOM   4077 C  CD1    . LEU   A  1 254 ? 76.356  -25.220 -22.524 1.00 52.30  ?  7052 LEU   B CD1    1 
ATOM   4078 C  CD2    . LEU   A  1 254 ? 78.166  -25.274 -24.268 1.00 63.50  ?  7052 LEU   B CD2    1 
ATOM   4079 H  H      A LEU   A  1 254 ? 78.748  -29.359 -21.662 0.48 64.10  ?  7052 LEU   B H      1 
ATOM   4080 H  H      B LEU   A  1 254 ? 78.743  -29.384 -21.663 0.52 64.10  ?  7052 LEU   B H      1 
ATOM   4081 H  HA     . LEU   A  1 254 ? 76.898  -27.547 -21.041 1.00 61.80  ?  7052 LEU   B HA     1 
ATOM   4082 H  HB2    . LEU   A  1 254 ? 78.700  -26.878 -22.259 1.00 70.57  ?  7052 LEU   B HB2    1 
ATOM   4083 H  HB3    . LEU   A  1 254 ? 78.283  -27.854 -23.442 1.00 70.57  ?  7052 LEU   B HB3    1 
ATOM   4084 H  HG     . LEU   A  1 254 ? 76.515  -26.589 -23.940 1.00 84.61  ?  7052 LEU   B HG     1 
ATOM   4085 H  HD11   . LEU   A  1 254 ? 75.898  -24.573 -23.083 1.00 63.28  ?  7052 LEU   B HD11   1 
ATOM   4086 H  HD12   . LEU   A  1 254 ? 75.709  -25.752 -22.036 1.00 63.28  ?  7052 LEU   B HD12   1 
ATOM   4087 H  HD13   . LEU   A  1 254 ? 76.944  -24.762 -21.903 1.00 63.28  ?  7052 LEU   B HD13   1 
ATOM   4088 H  HD21   . LEU   A  1 254 ? 77.668  -24.559 -24.694 1.00 76.72  ?  7052 LEU   B HD21   1 
ATOM   4089 H  HD22   . LEU   A  1 254 ? 78.851  -24.902 -23.691 1.00 76.72  ?  7052 LEU   B HD22   1 
ATOM   4090 H  HD23   . LEU   A  1 254 ? 78.573  -25.841 -24.942 1.00 76.72  ?  7052 LEU   B HD23   1 
ATOM   4091 N  N      . ARG   A  1 255 ? 74.830  -28.731 -21.722 1.00 54.92  ?  7053 ARG   B N      1 
ATOM   4092 C  CA     . ARG   A  1 255 ? 73.602  -29.379 -22.148 1.00 53.94  ?  7053 ARG   B CA     1 
ATOM   4093 C  C      . ARG   A  1 255 ? 72.756  -28.504 -23.064 1.00 55.20  ?  7053 ARG   B C      1 
ATOM   4094 O  O      . ARG   A  1 255 ? 71.724  -28.965 -23.565 1.00 59.44  ?  7053 ARG   B O      1 
ATOM   4095 C  CB     . ARG   A  1 255 ? 72.773  -29.783 -20.916 1.00 51.44  ?  7053 ARG   B CB     1 
ATOM   4096 C  CG     . ARG   A  1 255 ? 73.522  -30.662 -19.899 1.00 60.31  ?  7053 ARG   B CG     1 
ATOM   4097 C  CD     . ARG   A  1 255 ? 72.763  -30.835 -18.560 1.00 59.47  ?  7053 ARG   B CD     1 
ATOM   4098 N  NE     . ARG   A  1 255 ? 72.990  -32.152 -17.971 1.00 88.67  ?  7053 ARG   B NE     1 
ATOM   4099 C  CZ     . ARG   A  1 255 ? 73.692  -32.368 -16.868 1.00 78.23  ?  7053 ARG   B CZ     1 
ATOM   4100 N  NH1    . ARG   A  1 255 ? 74.204  -31.369 -16.166 1.00 64.42  ?  7053 ARG   B NH1    1 
ATOM   4101 N  NH2    . ARG   A  1 255 ? 73.872  -33.615 -16.448 1.00 72.62  ?  7053 ARG   B NH2    1 
ATOM   4102 H  H      . ARG   A  1 255 ? 74.734  -28.262 -21.007 1.00 66.43  ?  7053 ARG   B H      1 
ATOM   4103 H  HA     . ARG   A  1 255 ? 73.830  -30.184 -22.638 1.00 65.25  ?  7053 ARG   B HA     1 
ATOM   4104 H  HB2    . ARG   A  1 255 ? 72.493  -28.977 -20.455 1.00 62.25  ?  7053 ARG   B HB2    1 
ATOM   4105 H  HB3    . ARG   A  1 255 ? 71.997  -30.281 -21.217 1.00 62.25  ?  7053 ARG   B HB3    1 
ATOM   4106 H  HG2    . ARG   A  1 255 ? 73.654  -31.543 -20.282 1.00 72.90  ?  7053 ARG   B HG2    1 
ATOM   4107 H  HG3    . ARG   A  1 255 ? 74.380  -30.254 -19.703 1.00 72.90  ?  7053 ARG   B HG3    1 
ATOM   4108 H  HD2    . ARG   A  1 255 ? 73.069  -30.164 -17.930 1.00 71.89  ?  7053 ARG   B HD2    1 
ATOM   4109 H  HD3    . ARG   A  1 255 ? 71.811  -30.733 -18.717 1.00 71.89  ?  7053 ARG   B HD3    1 
ATOM   4110 H  HE     . ARG   A  1 255 ? 72.646  -32.833 -18.367 1.00 106.93 ?  7053 ARG   B HE     1 
ATOM   4111 H  HH11   . ARG   A  1 255 ? 74.085  -30.557 -16.424 1.00 77.83  ?  7053 ARG   B HH11   1 
ATOM   4112 H  HH12   . ARG   A  1 255 ? 74.656  -31.532 -15.453 1.00 77.83  ?  7053 ARG   B HH12   1 
ATOM   4113 H  HH21   . ARG   A  1 255 ? 73.535  -34.271 -16.891 1.00 87.67  ?  7053 ARG   B HH21   1 
ATOM   4114 H  HH22   . ARG   A  1 255 ? 74.325  -33.767 -15.733 1.00 87.67  ?  7053 ARG   B HH22   1 
ATOM   4115 N  N      . GLY   A  1 256 ? 73.170  -27.264 -23.291 1.00 52.39  ?  7054 GLY   B N      1 
ATOM   4116 C  CA     . GLY   A  1 256 ? 72.406  -26.333 -24.098 1.00 51.83  ?  7054 GLY   B CA     1 
ATOM   4117 C  C      . GLY   A  1 256 ? 70.982  -26.210 -23.619 1.00 49.21  ?  7054 GLY   B C      1 
ATOM   4118 O  O      . GLY   A  1 256 ? 70.066  -25.936 -24.407 1.00 61.81  ?  7054 GLY   B O      1 
ATOM   4119 H  H      . GLY   A  1 256 ? 73.903  -26.935 -22.983 1.00 63.39  ?  7054 GLY   B H      1 
ATOM   4120 H  HA2    . GLY   A  1 256 ? 72.820  -25.457 -24.060 1.00 62.72  ?  7054 GLY   B HA2    1 
ATOM   4121 H  HA3    . GLY   A  1 256 ? 72.395  -26.637 -25.019 1.00 62.72  ?  7054 GLY   B HA3    1 
ATOM   4122 N  N      . THR   A  1 257 ? 70.782  -26.418 -22.320 1.00 56.16  ?  7055 THR   B N      1 
ATOM   4123 C  CA     . THR   A  1 257 ? 69.456  -26.333 -21.722 1.00 50.41  ?  7055 THR   B CA     1 
ATOM   4124 C  C      . THR   A  1 257 ? 68.714  -25.105 -22.225 1.00 44.34  ?  7055 THR   B C      1 
ATOM   4125 O  O      . THR   A  1 257 ? 69.309  -24.051 -22.447 1.00 54.22  ?  7055 THR   B O      1 
ATOM   4126 C  CB     . THR   A  1 257 ? 69.563  -26.289 -20.193 1.00 42.73  ?  7055 THR   B CB     1 
ATOM   4127 O  OG1    . THR   A  1 257 ? 70.348  -27.397 -19.754 1.00 49.03  ?  7055 THR   B OG1    1 
ATOM   4128 C  CG2    . THR   A  1 257 ? 68.176  -26.345 -19.558 1.00 45.06  ?  7055 THR   B CG2    1 
ATOM   4129 H  H      . THR   A  1 257 ? 71.404  -26.612 -21.759 1.00 67.92  ?  7055 THR   B H      1 
ATOM   4130 H  HA     . THR   A  1 257 ? 68.948  -27.123 -21.966 1.00 61.01  ?  7055 THR   B HA     1 
ATOM   4131 H  HB     . THR   A  1 257 ? 69.982  -25.461 -19.910 1.00 51.80  ?  7055 THR   B HB     1 
ATOM   4132 H  HG1    . THR   A  1 257 ? 70.174  -27.572 -18.951 1.00 59.36  ?  7055 THR   B HG1    1 
ATOM   4133 H  HG21   . THR   A  1 257 ? 68.255  -26.468 -18.599 1.00 54.59  ?  7055 THR   B HG21   1 
ATOM   4134 H  HG22   . THR   A  1 257 ? 67.698  -25.519 -19.730 1.00 54.59  ?  7055 THR   B HG22   1 
ATOM   4135 H  HG23   . THR   A  1 257 ? 67.670  -27.085 -19.930 1.00 54.59  ?  7055 THR   B HG23   1 
ATOM   4136 N  N      . ALA   A  1 258 ? 67.405  -25.257 -22.410 1.00 45.86  ?  7056 ALA   B N      1 
ATOM   4137 C  CA     . ALA   A  1 258 ? 66.606  -24.213 -23.026 1.00 44.08  ?  7056 ALA   B CA     1 
ATOM   4138 C  C      . ALA   A  1 258 ? 66.282  -23.111 -22.025 1.00 47.24  ?  7056 ALA   B C      1 
ATOM   4139 O  O      . ALA   A  1 258 ? 66.113  -23.355 -20.824 1.00 52.95  ?  7056 ALA   B O      1 
ATOM   4140 C  CB     . ALA   A  1 258 ? 65.307  -24.783 -23.604 1.00 47.93  ?  7056 ALA   B CB     1 
ATOM   4141 H  H      . ALA   A  1 258 ? 66.960  -25.957 -22.186 1.00 55.55  ?  7056 ALA   B H      1 
ATOM   4142 H  HA     . ALA   A  1 258 ? 67.112  -23.822 -23.756 1.00 53.42  ?  7056 ALA   B HA     1 
ATOM   4143 H  HB1    . ALA   A  1 258 ? 64.787  -24.059 -23.987 1.00 58.04  ?  7056 ALA   B HB1    1 
ATOM   4144 H  HB2    . ALA   A  1 258 ? 65.525  -25.433 -24.289 1.00 58.04  ?  7056 ALA   B HB2    1 
ATOM   4145 H  HB3    . ALA   A  1 258 ? 64.805  -25.209 -22.891 1.00 58.04  ?  7056 ALA   B HB3    1 
ATOM   4146 N  N      . VAL   A  1 259 ? 66.193  -21.884 -22.542 1.00 47.76  ?  7057 VAL   B N      1 
ATOM   4147 C  CA     . VAL   A  1 259 ? 65.774  -20.714 -21.790 1.00 43.46  ?  7057 VAL   B CA     1 
ATOM   4148 C  C      . VAL   A  1 259 ? 64.494  -20.195 -22.420 1.00 43.46  ?  7057 VAL   B C      1 
ATOM   4149 O  O      . VAL   A  1 259 ? 64.390  -20.101 -23.647 1.00 52.50  ?  7057 VAL   B O      1 
ATOM   4150 C  CB     . VAL   A  1 259 ? 66.849  -19.610 -21.774 1.00 44.32  ?  7057 VAL   B CB     1 
ATOM   4151 C  CG1    . VAL   A  1 259 ? 66.326  -18.380 -21.035 1.00 48.30  ?  7057 VAL   B CG1    1 
ATOM   4152 C  CG2    . VAL   A  1 259 ? 68.132  -20.129 -21.156 1.00 44.66  ?  7057 VAL   B CG2    1 
ATOM   4153 H  H      . VAL   A  1 259 ? 66.380  -21.704 -23.362 1.00 57.84  ?  7057 VAL   B H      1 
ATOM   4154 H  HA     . VAL   A  1 259 ? 65.602  -20.972 -20.870 1.00 52.68  ?  7057 VAL   B HA     1 
ATOM   4155 H  HB     . VAL   A  1 259 ? 67.054  -19.342 -22.683 1.00 53.70  ?  7057 VAL   B HB     1 
ATOM   4156 H  HG11   . VAL   A  1 259 ? 67.062  -17.767 -20.883 1.00 58.48  ?  7057 VAL   B HG11   1 
ATOM   4157 H  HG12   . VAL   A  1 259 ? 65.645  -17.952 -21.577 1.00 58.48  ?  7057 VAL   B HG12   1 
ATOM   4158 H  HG13   . VAL   A  1 259 ? 65.947  -18.659 -20.187 1.00 58.48  ?  7057 VAL   B HG13   1 
ATOM   4159 H  HG21   . VAL   A  1 259 ? 68.782  -19.410 -21.127 1.00 54.11  ?  7057 VAL   B HG21   1 
ATOM   4160 H  HG22   . VAL   A  1 259 ? 67.946  -20.444 -20.258 1.00 54.11  ?  7057 VAL   B HG22   1 
ATOM   4161 H  HG23   . VAL   A  1 259 ? 68.470  -20.859 -21.698 1.00 54.11  ?  7057 VAL   B HG23   1 
ATOM   4162 N  N      . MET   A  1 260 ? 63.521  -19.853 -21.581 1.00 49.81  ?  7058 MET   B N      1 
ATOM   4163 C  CA     . MET   A  1 260 ? 62.292  -19.212 -22.033 1.00 45.04  ?  7058 MET   B CA     1 
ATOM   4164 C  C      . MET   A  1 260 ? 61.954  -18.093 -21.064 1.00 46.87  ?  7058 MET   B C      1 
ATOM   4165 O  O      . MET   A  1 260 ? 61.943  -18.316 -19.851 1.00 51.19  ?  7058 MET   B O      1 
ATOM   4166 C  CB     . MET   A  1 260 ? 61.115  -20.191 -22.099 1.00 53.33  ?  7058 MET   B CB     1 
ATOM   4167 C  CG     . MET   A  1 260 ? 61.128  -21.140 -23.254 1.00 63.57  ?  7058 MET   B CG     1 
ATOM   4168 S  SD     . MET   A  1 260 ? 59.843  -22.411 -23.143 1.00 77.36  ?  7058 MET   B SD     1 
ATOM   4169 C  CE     . MET   A  1 260 ? 59.123  -22.133 -21.538 1.00 69.32  ?  7058 MET   B CE     1 
ATOM   4170 H  H      . MET   A  1 260 ? 63.550  -19.984 -20.732 1.00 60.29  ?  7058 MET   B H      1 
ATOM   4171 H  HA     . MET   A  1 260 ? 62.435  -18.862 -22.925 1.00 54.56  ?  7058 MET   B HA     1 
ATOM   4172 H  HB2    . MET   A  1 260 ? 61.116  -20.724 -21.288 1.00 64.52  ?  7058 MET   B HB2    1 
ATOM   4173 H  HB3    . MET   A  1 260 ? 60.294  -19.677 -22.157 1.00 64.52  ?  7058 MET   B HB3    1 
ATOM   4174 H  HG2    . MET   A  1 260 ? 60.985  -20.640 -24.074 1.00 76.81  ?  7058 MET   B HG2    1 
ATOM   4175 H  HG3    . MET   A  1 260 ? 61.988  -21.587 -23.285 1.00 76.81  ?  7058 MET   B HG3    1 
ATOM   4176 H  HE1    . MET   A  1 260 ? 58.291  -22.628 -21.475 1.00 83.71  ?  7058 MET   B HE1    1 
ATOM   4177 H  HE2    . MET   A  1 260 ? 59.743  -22.439 -20.857 1.00 83.71  ?  7058 MET   B HE2    1 
ATOM   4178 H  HE3    . MET   A  1 260 ? 58.953  -21.184 -21.428 1.00 83.71  ?  7058 MET   B HE3    1 
ATOM   4179 N  N      . SER   A  1 261 ? 61.689  -16.896 -21.575 1.00 55.32  ?  7059 SER   B N      1 
ATOM   4180 C  CA     . SER   A  1 261 ? 60.992  -15.920 -20.754 1.00 58.61  ?  7059 SER   B CA     1 
ATOM   4181 C  C      . SER   A  1 261 ? 59.536  -16.374 -20.645 1.00 63.11  ?  7059 SER   B C      1 
ATOM   4182 O  O      . SER   A  1 261 ? 58.945  -16.833 -21.624 1.00 71.28  ?  7059 SER   B O      1 
ATOM   4183 C  CB     . SER   A  1 261 ? 61.107  -14.520 -21.359 1.00 61.77  ?  7059 SER   B CB     1 
ATOM   4184 O  OG     . SER   A  1 261 ? 60.284  -13.601 -20.667 1.00 76.26  ?  7059 SER   B OG     1 
ATOM   4185 H  H      . SER   A  1 261 ? 61.895  -16.634 -22.368 1.00 66.91  ?  7059 SER   B H      1 
ATOM   4186 H  HA     . SER   A  1 261 ? 61.379  -15.854 -19.867 1.00 70.85  ?  7059 SER   B HA     1 
ATOM   4187 H  HB2    . SER   A  1 261 ? 62.029  -14.225 -21.299 1.00 74.64  ?  7059 SER   B HB2    1 
ATOM   4188 H  HB3    . SER   A  1 261 ? 60.829  -14.554 -22.288 1.00 74.64  ?  7059 SER   B HB3    1 
ATOM   4189 H  HG     . SER   A  1 261 ? 60.340  -12.841 -21.022 1.00 92.03  ?  7059 SER   B HG     1 
ATOM   4190 N  N      . LEU   A  1 262 ? 58.986  -16.325 -19.435 1.00 63.73  ?  7060 LEU   B N      1 
ATOM   4191 C  CA     . LEU   A  1 262 ? 57.631  -16.789 -19.165 1.00 67.23  ?  7060 LEU   B CA     1 
ATOM   4192 C  C      . LEU   A  1 262 ? 57.048  -16.015 -17.993 1.00 76.58  ?  7060 LEU   B C      1 
ATOM   4193 O  O      . LEU   A  1 262 ? 57.777  -15.563 -17.110 1.00 72.83  ?  7060 LEU   B O      1 
ATOM   4194 C  CB     . LEU   A  1 262 ? 57.593  -18.298 -18.857 1.00 70.29  ?  7060 LEU   B CB     1 
ATOM   4195 C  CG     . LEU   A  1 262 ? 56.962  -19.289 -19.840 1.00 69.99  ?  7060 LEU   B CG     1 
ATOM   4196 C  CD1    . LEU   A  1 262 ? 57.546  -19.155 -21.239 1.00 65.02  ?  7060 LEU   B CD1    1 
ATOM   4197 C  CD2    . LEU   A  1 262 ? 57.103  -20.746 -19.358 1.00 66.64  ?  7060 LEU   B CD2    1 
ATOM   4198 H  H      . LEU   A  1 262 ? 59.386  -16.019 -18.738 1.00 77.00  ?  7060 LEU   B H      1 
ATOM   4199 H  HA     . LEU   A  1 262 ? 57.083  -16.618 -19.947 1.00 81.20  ?  7060 LEU   B HA     1 
ATOM   4200 H  HB2    . LEU   A  1 262 ? 58.512  -18.586 -18.743 1.00 84.86  ?  7060 LEU   B HB2    1 
ATOM   4201 H  HB3    . LEU   A  1 262 ? 57.106  -18.404 -18.025 1.00 84.86  ?  7060 LEU   B HB3    1 
ATOM   4202 H  HG     . LEU   A  1 262 ? 56.018  -19.072 -19.883 1.00 84.50  ?  7060 LEU   B HG     1 
ATOM   4203 H  HD11   . LEU   A  1 262 ? 57.287  -19.928 -21.764 1.00 78.55  ?  7060 LEU   B HD11   1 
ATOM   4204 H  HD12   . LEU   A  1 262 ? 57.202  -18.346 -21.648 1.00 78.55  ?  7060 LEU   B HD12   1 
ATOM   4205 H  HD13   . LEU   A  1 262 ? 58.513  -19.108 -21.174 1.00 78.55  ?  7060 LEU   B HD13   1 
ATOM   4206 H  HD21   . LEU   A  1 262 ? 56.748  -21.339 -20.039 1.00 80.49  ?  7060 LEU   B HD21   1 
ATOM   4207 H  HD22   . LEU   A  1 262 ? 58.041  -20.940 -19.207 1.00 80.49  ?  7060 LEU   B HD22   1 
ATOM   4208 H  HD23   . LEU   A  1 262 ? 56.605  -20.856 -18.533 1.00 80.49  ?  7060 LEU   B HD23   1 
ATOM   4209 N  N      A LYS   A  1 263 ? 55.721  -15.879 -17.993 0.81 89.05  ?  7061 LYS   B N      1 
ATOM   4210 N  N      B LYS   A  1 263 ? 55.730  -15.853 -18.006 0.19 88.92  ?  7061 LYS   B N      1 
ATOM   4211 C  CA     A LYS   A  1 263 ? 54.983  -15.188 -16.940 0.81 92.35  ?  7061 LYS   B CA     1 
ATOM   4212 C  CA     B LYS   A  1 263 ? 55.025  -15.200 -16.915 0.19 92.21  ?  7061 LYS   B CA     1 
ATOM   4213 C  C      A LYS   A  1 263 ? 54.384  -16.202 -15.970 0.81 89.41  ?  7061 LYS   B C      1 
ATOM   4214 C  C      B LYS   A  1 263 ? 54.571  -16.242 -15.893 0.19 89.67  ?  7061 LYS   B C      1 
ATOM   4215 O  O      A LYS   A  1 263 ? 54.127  -17.351 -16.337 0.81 92.52  ?  7061 LYS   B O      1 
ATOM   4216 O  O      B LYS   A  1 263 ? 54.608  -17.451 -16.139 0.19 91.22  ?  7061 LYS   B O      1 
ATOM   4217 C  CB     A LYS   A  1 263 ? 53.864  -14.321 -17.533 0.81 94.22  ?  7061 LYS   B CB     1 
ATOM   4218 C  CB     B LYS   A  1 263 ? 53.833  -14.408 -17.455 0.19 94.12  ?  7061 LYS   B CB     1 
ATOM   4219 C  CG     A LYS   A  1 263 ? 54.293  -13.289 -18.563 0.81 95.09  ?  7061 LYS   B CG     1 
ATOM   4220 C  CG     B LYS   A  1 263 ? 54.211  -13.151 -18.217 0.19 94.85  ?  7061 LYS   B CG     1 
ATOM   4221 C  CD     A LYS   A  1 263 ? 53.108  -12.492 -19.127 0.81 100.67 ?  7061 LYS   B CD     1 
ATOM   4222 C  CD     B LYS   A  1 263 ? 53.844  -13.208 -19.703 0.19 96.92  ?  7061 LYS   B CD     1 
ATOM   4223 C  CE     A LYS   A  1 263 ? 52.138  -13.349 -19.936 0.81 102.90 ?  7061 LYS   B CE     1 
ATOM   4224 C  CE     B LYS   A  1 263 ? 52.368  -13.463 -19.939 0.19 101.66 ?  7061 LYS   B CE     1 
ATOM   4225 N  NZ     A LYS   A  1 263 ? 51.886  -12.814 -21.310 0.81 96.49  ?  7061 LYS   B NZ     1 
ATOM   4226 N  NZ     B LYS   A  1 263 ? 52.103  -14.005 -21.313 0.19 97.76  ?  7061 LYS   B NZ     1 
ATOM   4227 H  H      A LYS   A  1 263 ? 55.212  -16.189 -18.613 0.81 107.38 ?  7061 LYS   B H      1 
ATOM   4228 H  H      B LYS   A  1 263 ? 55.217  -16.115 -18.645 0.19 107.23 ?  7061 LYS   B H      1 
ATOM   4229 H  HA     A LYS   A  1 263 ? 55.588  -14.608 -16.450 0.81 111.34 ?  7061 LYS   B HA     1 
ATOM   4230 H  HA     B LYS   A  1 263 ? 55.617  -14.575 -16.468 0.19 111.18 ?  7061 LYS   B HA     1 
ATOM   4231 H  HB2    A LYS   A  1 263 ? 53.224  -14.908 -17.964 0.81 113.58 ?  7061 LYS   B HB2    1 
ATOM   4232 H  HB2    B LYS   A  1 263 ? 53.330  -14.978 -18.058 0.19 113.47 ?  7061 LYS   B HB2    1 
ATOM   4233 H  HB3    A LYS   A  1 263 ? 53.437  -13.841 -16.807 0.81 113.58 ?  7061 LYS   B HB3    1 
ATOM   4234 H  HB3    B LYS   A  1 263 ? 53.274  -14.142 -16.708 0.19 113.47 ?  7061 LYS   B HB3    1 
ATOM   4235 H  HG2    A LYS   A  1 263 ? 54.906  -12.662 -18.148 0.81 114.63 ?  7061 LYS   B HG2    1 
ATOM   4236 H  HG2    B LYS   A  1 263 ? 53.747  -12.394 -17.826 0.19 114.34 ?  7061 LYS   B HG2    1 
ATOM   4237 H  HG3    A LYS   A  1 263 ? 54.730  -13.741 -19.302 0.81 114.63 ?  7061 LYS   B HG3    1 
ATOM   4238 H  HG3    B LYS   A  1 263 ? 55.170  -13.021 -18.153 0.19 114.34 ?  7061 LYS   B HG3    1 
ATOM   4239 H  HD2    A LYS   A  1 263 ? 52.614  -12.098 -18.390 0.81 121.33 ?  7061 LYS   B HD2    1 
ATOM   4240 H  HD2    B LYS   A  1 263 ? 54.071  -12.360 -20.117 0.19 116.82 ?  7061 LYS   B HD2    1 
ATOM   4241 H  HD3    A LYS   A  1 263 ? 53.446  -11.794 -19.709 0.81 121.33 ?  7061 LYS   B HD3    1 
ATOM   4242 H  HD3    B LYS   A  1 263 ? 54.342  -13.926 -20.123 0.19 116.82 ?  7061 LYS   B HD3    1 
ATOM   4243 H  HE2    A LYS   A  1 263 ? 52.507  -14.241 -20.027 0.81 124.00 ?  7061 LYS   B HE2    1 
ATOM   4244 H  HE2    B LYS   A  1 263 ? 52.048  -14.110 -19.291 0.19 122.51 ?  7061 LYS   B HE2    1 
ATOM   4245 H  HE3    A LYS   A  1 263 ? 51.288  -13.387 -19.471 0.81 124.00 ?  7061 LYS   B HE3    1 
ATOM   4246 H  HE3    B LYS   A  1 263 ? 51.881  -12.629 -19.844 0.19 122.51 ?  7061 LYS   B HE3    1 
ATOM   4247 H  HZ1    A LYS   A  1 263 ? 51.315  -13.343 -21.742 0.81 116.31 ?  7061 LYS   B HZ1    1 
ATOM   4248 H  HZ1    B LYS   A  1 263 ? 52.538  -14.773 -21.426 0.19 117.84 ?  7061 LYS   B HZ1    1 
ATOM   4249 H  HZ2    A LYS   A  1 263 ? 51.540  -11.996 -21.259 0.81 116.31 ?  7061 LYS   B HZ2    1 
ATOM   4250 H  HZ2    B LYS   A  1 263 ? 51.231  -14.149 -21.420 0.19 117.84 ?  7061 LYS   B HZ2    1 
ATOM   4251 H  HZ3    A LYS   A  1 263 ? 52.649  -12.777 -21.767 0.81 116.31 ?  7061 LYS   B HZ3    1 
ATOM   4252 H  HZ3    B LYS   A  1 263 ? 52.377  -13.424 -21.928 0.19 117.84 ?  7061 LYS   B HZ3    1 
ATOM   4253 N  N      . GLU   A  1 264 ? 54.139  -15.760 -14.726 1.00 84.10  ?  7062 GLU   B N      1 
ATOM   4254 C  CA     . GLU   A  1 264 ? 53.678  -16.683 -13.689 1.00 95.57  ?  7062 GLU   B CA     1 
ATOM   4255 C  C      . GLU   A  1 264 ? 52.420  -17.435 -14.107 1.00 92.24  ?  7062 GLU   B C      1 
ATOM   4256 O  O      . GLU   A  1 264 ? 52.203  -18.566 -13.661 1.00 93.77  ?  7062 GLU   B O      1 
ATOM   4257 C  CB     . GLU   A  1 264 ? 53.434  -15.946 -12.371 1.00 97.42  ?  7062 GLU   B CB     1 
ATOM   4258 C  CG     . GLU   A  1 264 ? 53.009  -16.840 -11.207 1.00 109.44 ?  7062 GLU   B CG     1 
ATOM   4259 C  CD     . GLU   A  1 264 ? 53.919  -18.035 -10.981 1.00 105.73 ?  7062 GLU   B CD     1 
ATOM   4260 O  OE1    . GLU   A  1 264 ? 55.151  -17.857 -10.921 1.00 101.36 ?  7062 GLU   B OE1    1 
ATOM   4261 O  OE2    . GLU   A  1 264 ? 53.396  -19.162 -10.852 1.00 101.76 ?  7062 GLU   B OE2    1 
ATOM   4262 H  H      A GLU   A  1 264 ? 54.230  -14.945 -14.466 0.81 101.45 ?  7062 GLU   B H      1 
ATOM   4263 H  H      B GLU   A  1 264 ? 54.103  -14.927 -14.516 0.19 101.45 ?  7062 GLU   B H      1 
ATOM   4264 H  HA     . GLU   A  1 264 ? 54.383  -17.333 -13.540 1.00 115.20 ?  7062 GLU   B HA     1 
ATOM   4265 H  HB2    . GLU   A  1 264 ? 54.256  -15.500 -12.111 1.00 117.42 ?  7062 GLU   B HB2    1 
ATOM   4266 H  HB3    . GLU   A  1 264 ? 52.731  -15.292 -12.509 1.00 117.42 ?  7062 GLU   B HB3    1 
ATOM   4267 H  HG2    . GLU   A  1 264 ? 53.008  -16.312 -10.393 1.00 131.85 ?  7062 GLU   B HG2    1 
ATOM   4268 H  HG3    . GLU   A  1 264 ? 52.117  -17.178 -11.384 1.00 131.85 ?  7062 GLU   B HG3    1 
ATOM   4269 N  N      . GLY   A  1 265 ? 51.591  -16.847 -14.968 1.00 90.79  ?  7063 GLY   B N      1 
ATOM   4270 C  CA     . GLY   A  1 265 ? 50.407  -17.548 -15.425 1.00 94.97  ?  7063 GLY   B CA     1 
ATOM   4271 C  C      . GLY   A  1 265 ? 50.699  -18.784 -16.248 1.00 95.91  ?  7063 GLY   B C      1 
ATOM   4272 O  O      . GLY   A  1 265 ? 49.869  -19.701 -16.294 1.00 95.20  ?  7063 GLY   B O      1 
ATOM   4273 H  H      . GLY   A  1 265 ? 51.694  -16.057 -15.294 1.00 109.47 ?  7063 GLY   B H      1 
ATOM   4274 H  HA2    . GLY   A  1 265 ? 49.885  -17.819 -14.653 1.00 114.48 ?  7063 GLY   B HA2    1 
ATOM   4275 H  HA3    . GLY   A  1 265 ? 49.876  -16.946 -15.969 1.00 114.48 ?  7063 GLY   B HA3    1 
ATOM   4276 N  N      . GLN   A  1 266 ? 51.867  -18.841 -16.875 1.00 85.44  ?  7064 GLN   B N      1 
ATOM   4277 C  CA     . GLN   A  1 266 ? 52.186  -19.865 -17.859 1.00 84.69  ?  7064 GLN   B CA     1 
ATOM   4278 C  C      . GLN   A  1 266 ? 52.956  -21.036 -17.274 1.00 88.02  ?  7064 GLN   B C      1 
ATOM   4279 O  O      . GLN   A  1 266 ? 53.279  -21.972 -18.010 1.00 79.46  ?  7064 GLN   B O      1 
ATOM   4280 C  CB     . GLN   A  1 266 ? 52.996  -19.258 -19.006 1.00 95.35  ?  7064 GLN   B CB     1 
ATOM   4281 C  CG     . GLN   A  1 266 ? 52.671  -17.843 -19.325 1.00 95.65  ?  7064 GLN   B CG     1 
ATOM   4282 C  CD     . GLN   A  1 266 ? 53.379  -17.347 -20.570 1.00 87.87  ?  7064 GLN   B CD     1 
ATOM   4283 O  OE1    . GLN   A  1 266 ? 54.150  -16.398 -20.526 1.00 86.66  ?  7064 GLN   B OE1    1 
ATOM   4284 N  NE2    . GLN   A  1 266 ? 53.169  -18.034 -21.668 1.00 81.01  ?  7064 GLN   B NE2    1 
ATOM   4285 H  H      . GLN   A  1 266 ? 52.507  -18.282 -16.745 1.00 103.05 ?  7064 GLN   B H      1 
ATOM   4286 H  HA     . GLN   A  1 266 ? 51.353  -20.206 -18.219 1.00 102.15 ?  7064 GLN   B HA     1 
ATOM   4287 H  HB2    . GLN   A  1 266 ? 53.936  -19.294 -18.770 1.00 114.94 ?  7064 GLN   B HB2    1 
ATOM   4288 H  HB3    . GLN   A  1 266 ? 52.834  -19.781 -19.806 1.00 114.94 ?  7064 GLN   B HB3    1 
ATOM   4289 H  HG2    . GLN   A  1 266 ? 51.716  -17.763 -19.470 1.00 115.30 ?  7064 GLN   B HG2    1 
ATOM   4290 H  HG3    . GLN   A  1 266 ? 52.942  -17.281 -18.582 1.00 115.30 ?  7064 GLN   B HG3    1 
ATOM   4291 H  HE21   . GLN   A  1 266 ? 52.655  -18.723 -21.653 1.00 97.74  ?  7064 GLN   B HE21   1 
ATOM   4292 H  HE22   . GLN   A  1 266 ? 53.547  -17.795 -22.403 1.00 97.74  ?  7064 GLN   B HE22   1 
ATOM   4293 N  N      . ILE   A  1 267 ? 53.285  -21.001 -15.986 1.00 92.10  ?  7065 ILE   B N      1 
ATOM   4294 C  CA     . ILE   A  1 267 ? 54.009  -22.093 -15.341 1.00 85.39  ?  7065 ILE   B CA     1 
ATOM   4295 C  C      . ILE   A  1 267 ? 52.990  -23.148 -14.921 1.00 83.09  ?  7065 ILE   B C      1 
ATOM   4296 O  O      . ILE   A  1 267 ? 52.349  -23.030 -13.872 1.00 89.78  ?  7065 ILE   B O      1 
ATOM   4297 C  CB     . ILE   A  1 267 ? 54.831  -21.615 -14.144 1.00 88.96  ?  7065 ILE   B CB     1 
ATOM   4298 C  CG1    . ILE   A  1 267 ? 55.548  -20.283 -14.393 1.00 80.46  ?  7065 ILE   B CG1    1 
ATOM   4299 C  CG2    . ILE   A  1 267 ? 55.804  -22.717 -13.710 1.00 69.07  ?  7065 ILE   B CG2    1 
ATOM   4300 C  CD1    . ILE   A  1 267 ? 56.753  -20.350 -15.269 1.00 68.05  ?  7065 ILE   B CD1    1 
ATOM   4301 H  H      . ILE   A  1 267 ? 53.098  -20.348 -15.458 1.00 111.05 ?  7065 ILE   B H      1 
ATOM   4302 H  HA     . ILE   A  1 267 ? 54.608  -22.486 -15.994 1.00 103.00 ?  7065 ILE   B HA     1 
ATOM   4303 H  HB     . ILE   A  1 267 ? 54.210  -21.436 -13.421 1.00 107.28 ?  7065 ILE   B HB     1 
ATOM   4304 H  HG12   . ILE   A  1 267 ? 54.921  -19.674 -14.813 1.00 97.07  ?  7065 ILE   B HG12   1 
ATOM   4305 H  HG13   . ILE   A  1 267 ? 55.834  -19.926 -13.538 1.00 97.07  ?  7065 ILE   B HG13   1 
ATOM   4306 H  HG21   . ILE   A  1 267 ? 56.360  -22.382 -12.990 1.00 83.40  ?  7065 ILE   B HG21   1 
ATOM   4307 H  HG22   . ILE   A  1 267 ? 55.295  -23.485 -13.405 1.00 83.40  ?  7065 ILE   B HG22   1 
ATOM   4308 H  HG23   . ILE   A  1 267 ? 56.357  -22.966 -14.467 1.00 83.40  ?  7065 ILE   B HG23   1 
ATOM   4309 H  HD11   . ILE   A  1 267 ? 57.086  -19.451 -15.419 1.00 82.18  ?  7065 ILE   B HD11   1 
ATOM   4310 H  HD12   . ILE   A  1 267 ? 57.433  -20.885 -14.831 1.00 82.18  ?  7065 ILE   B HD12   1 
ATOM   4311 H  HD13   . ILE   A  1 267 ? 56.507  -20.756 -16.115 1.00 82.18  ?  7065 ILE   B HD13   1 
ATOM   4312 N  N      . ASN   A  1 268 ? 52.860  -24.193 -15.729 1.00 85.06  ?  7066 ASN   B N      1 
ATOM   4313 C  CA     . ASN   A  1 268 ? 51.916  -25.270 -15.472 1.00 85.32  ?  7066 ASN   B CA     1 
ATOM   4314 C  C      . ASN   A  1 268 ? 52.624  -26.497 -14.924 1.00 80.39  ?  7066 ASN   B C      1 
ATOM   4315 O  O      . ASN   A  1 268 ? 53.670  -26.362 -14.296 1.00 81.09  ?  7066 ASN   B O      1 
ATOM   4316 C  CB     . ASN   A  1 268 ? 51.173  -25.599 -16.755 1.00 78.01  ?  7066 ASN   B CB     1 
ATOM   4317 C  CG     . ASN   A  1 268 ? 52.104  -26.044 -17.876 1.00 76.56  ?  7066 ASN   B CG     1 
ATOM   4318 O  OD1    . ASN   A  1 268 ? 52.940  -26.915 -17.684 1.00 81.37  ?  7066 ASN   B OD1    1 
ATOM   4319 N  ND2    . ASN   A  1 268 ? 52.021  -25.377 -19.022 1.00 79.45  ?  7066 ASN   B ND2    1 
ATOM   4320 H  H      . ASN   A  1 268 ? 53.318  -24.304 -16.448 1.00 102.59 ?  7066 ASN   B H      1 
ATOM   4321 H  HA     . ASN   A  1 268 ? 51.271  -24.991 -14.804 1.00 102.91 ?  7066 ASN   B HA     1 
ATOM   4322 H  HB2    . ASN   A  1 268 ? 50.546  -26.318 -16.582 1.00 94.13  ?  7066 ASN   B HB2    1 
ATOM   4323 H  HB3    . ASN   A  1 268 ? 50.697  -24.809 -17.057 1.00 94.13  ?  7066 ASN   B HB3    1 
ATOM   4324 H  HD21   . ASN   A  1 268 ? 52.527  -25.593 -19.683 1.00 95.86  ?  7066 ASN   B HD21   1 
ATOM   4325 H  HD22   . ASN   A  1 268 ? 51.460  -24.730 -19.103 1.00 95.86  ?  7066 ASN   B HD22   1 
ATOM   4326 N  N      . ASP   A  1 269 ? 52.049  -27.683 -15.125 1.00 79.82  ?  7067 ASP   B N      1 
ATOM   4327 C  CA     . ASP   A  1 269 ? 52.682  -28.908 -14.651 1.00 71.85  ?  7067 ASP   B CA     1 
ATOM   4328 C  C      . ASP   A  1 269 ? 53.717  -29.443 -15.640 1.00 66.57  ?  7067 ASP   B C      1 
ATOM   4329 O  O      . ASP   A  1 269 ? 54.765  -29.946 -15.218 1.00 70.80  ?  7067 ASP   B O      1 
ATOM   4330 C  CB     . ASP   A  1 269 ? 51.615  -29.964 -14.359 1.00 78.72  ?  7067 ASP   B CB     1 
ATOM   4331 C  CG     . ASP   A  1 269 ? 50.681  -29.555 -13.235 1.00 88.54  ?  7067 ASP   B CG     1 
ATOM   4332 O  OD1    . ASP   A  1 269 ? 51.057  -28.679 -12.434 1.00 79.64  ?  7067 ASP   B OD1    1 
ATOM   4333 O  OD2    . ASP   A  1 269 ? 49.573  -30.114 -13.138 1.00 92.61  ?  7067 ASP   B OD2    1 
ATOM   4334 H  H      . ASP   A  1 269 ? 51.300  -27.802 -15.530 1.00 96.30  ?  7067 ASP   B H      1 
ATOM   4335 H  HA     . ASP   A  1 269 ? 53.146  -28.726 -13.819 1.00 86.74  ?  7067 ASP   B HA     1 
ATOM   4336 H  HB2    . ASP   A  1 269 ? 51.081  -30.104 -15.157 1.00 94.99  ?  7067 ASP   B HB2    1 
ATOM   4337 H  HB3    . ASP   A  1 269 ? 52.051  -30.791 -14.102 1.00 94.99  ?  7067 ASP   B HB3    1 
ATOM   4338 N  N      . MET   A  1 270 ? 53.469  -29.323 -16.949 1.00 63.90  ?  7068 MET   B N      1 
ATOM   4339 C  CA     . MET   A  1 270 ? 54.501  -29.680 -17.917 1.00 66.84  ?  7068 MET   B CA     1 
ATOM   4340 C  C      . MET   A  1 270 ? 55.762  -28.862 -17.661 1.00 62.04  ?  7068 MET   B C      1 
ATOM   4341 O  O      . MET   A  1 270 ? 56.860  -29.412 -17.524 1.00 60.18  ?  7068 MET   B O      1 
ATOM   4342 C  CB     . MET   A  1 270 ? 53.996  -29.451 -19.343 1.00 61.34  ?  7068 MET   B CB     1 
ATOM   4343 C  CG     . MET   A  1 270 ? 55.070  -29.368 -20.412 1.00 64.16  ?  7068 MET   B CG     1 
ATOM   4344 S  SD     . MET   A  1 270 ? 55.477  -30.954 -21.183 1.00 109.81 ?  7068 MET   B SD     1 
ATOM   4345 C  CE     . MET   A  1 270 ? 56.743  -31.578 -20.114 1.00 75.47  ?  7068 MET   B CE     1 
ATOM   4346 H  H      . MET   A  1 270 ? 52.730  -29.044 -17.290 1.00 77.20  ?  7068 MET   B H      1 
ATOM   4347 H  HA     . MET   A  1 270 ? 54.700  -30.625 -17.829 1.00 80.74  ?  7068 MET   B HA     1 
ATOM   4348 H  HB2    . MET   A  1 270 ? 53.409  -30.186 -19.580 1.00 74.13  ?  7068 MET   B HB2    1 
ATOM   4349 H  HB3    . MET   A  1 270 ? 53.504  -28.615 -19.362 1.00 74.13  ?  7068 MET   B HB3    1 
ATOM   4350 H  HG2    . MET   A  1 270 ? 54.765  -28.770 -21.112 1.00 77.51  ?  7068 MET   B HG2    1 
ATOM   4351 H  HG3    . MET   A  1 270 ? 55.882  -29.020 -20.009 1.00 77.51  ?  7068 MET   B HG3    1 
ATOM   4352 H  HE1    . MET   A  1 270 ? 56.665  -32.543 -20.063 1.00 91.09  ?  7068 MET   B HE1    1 
ATOM   4353 H  HE2    . MET   A  1 270 ? 57.610  -31.334 -20.474 1.00 91.09  ?  7068 MET   B HE2    1 
ATOM   4354 H  HE3    . MET   A  1 270 ? 56.631  -31.190 -19.232 1.00 91.09  ?  7068 MET   B HE3    1 
ATOM   4355 N  N      . ILE   A  1 271 ? 55.621  -27.536 -17.610 1.00 61.01  ?  7069 ILE   B N      1 
ATOM   4356 C  CA     . ILE   A  1 271 ? 56.757  -26.661 -17.331 1.00 60.36  ?  7069 ILE   B CA     1 
ATOM   4357 C  C      . ILE   A  1 271 ? 57.451  -27.089 -16.043 1.00 56.24  ?  7069 ILE   B C      1 
ATOM   4358 O  O      . ILE   A  1 271 ? 58.670  -27.299 -16.011 1.00 55.37  ?  7069 ILE   B O      1 
ATOM   4359 C  CB     . ILE   A  1 271 ? 56.282  -25.200 -17.249 1.00 59.10  ?  7069 ILE   B CB     1 
ATOM   4360 C  CG1    . ILE   A  1 271 ? 55.707  -24.737 -18.588 1.00 63.12  ?  7069 ILE   B CG1    1 
ATOM   4361 C  CG2    . ILE   A  1 271 ? 57.437  -24.291 -16.823 1.00 54.16  ?  7069 ILE   B CG2    1 
ATOM   4362 C  CD1    . ILE   A  1 271 ? 56.735  -24.650 -19.687 1.00 58.38  ?  7069 ILE   B CD1    1 
ATOM   4363 H  H      . ILE   A  1 271 ? 54.879  -27.119 -17.733 1.00 73.74  ?  7069 ILE   B H      1 
ATOM   4364 H  HA     . ILE   A  1 271 ? 57.398  -26.739 -18.055 1.00 72.96  ?  7069 ILE   B HA     1 
ATOM   4365 H  HB     . ILE   A  1 271 ? 55.578  -25.150 -16.584 1.00 71.44  ?  7069 ILE   B HB     1 
ATOM   4366 H  HG12   . ILE   A  1 271 ? 55.025  -25.366 -18.869 1.00 76.27  ?  7069 ILE   B HG12   1 
ATOM   4367 H  HG13   . ILE   A  1 271 ? 55.320  -23.856 -18.474 1.00 76.27  ?  7069 ILE   B HG13   1 
ATOM   4368 H  HG21   . ILE   A  1 271 ? 57.199  -23.369 -17.010 1.00 65.52  ?  7069 ILE   B HG21   1 
ATOM   4369 H  HG22   . ILE   A  1 271 ? 57.594  -24.405 -15.873 1.00 65.52  ?  7069 ILE   B HG22   1 
ATOM   4370 H  HG23   . ILE   A  1 271 ? 58.232  -24.535 -17.322 1.00 65.52  ?  7069 ILE   B HG23   1 
ATOM   4371 H  HD11   . ILE   A  1 271 ? 56.298  -24.370 -20.506 1.00 70.57  ?  7069 ILE   B HD11   1 
ATOM   4372 H  HD12   . ILE   A  1 271 ? 57.412  -24.003 -19.435 1.00 70.57  ?  7069 ILE   B HD12   1 
ATOM   4373 H  HD13   . ILE   A  1 271 ? 57.140  -25.522 -19.810 1.00 70.57  ?  7069 ILE   B HD13   1 
ATOM   4374 N  N      . LEU   A  1 272 ? 56.675  -27.215 -14.960 1.00 59.05  ?  7070 LEU   B N      1 
ATOM   4375 C  CA     . LEU   A  1 272 ? 57.239  -27.578 -13.663 1.00 54.88  ?  7070 LEU   B CA     1 
ATOM   4376 C  C      . LEU   A  1 272 ? 57.929  -28.933 -13.735 1.00 48.44  ?  7070 LEU   B C      1 
ATOM   4377 O  O      . LEU   A  1 272 ? 58.993  -29.130 -13.143 1.00 51.32  ?  7070 LEU   B O      1 
ATOM   4378 C  CB     . LEU   A  1 272 ? 56.130  -27.582 -12.613 1.00 60.42  ?  7070 LEU   B CB     1 
ATOM   4379 C  CG     . LEU   A  1 272 ? 55.872  -26.208 -11.983 1.00 69.92  ?  7070 LEU   B CG     1 
ATOM   4380 C  CD1    . LEU   A  1 272 ? 54.577  -26.193 -11.166 1.00 78.24  ?  7070 LEU   B CD1    1 
ATOM   4381 C  CD2    . LEU   A  1 272 ? 57.029  -25.763 -11.106 1.00 68.49  ?  7070 LEU   B CD2    1 
ATOM   4382 H  H      . LEU   A  1 272 ? 55.823  -27.096 -14.952 1.00 71.38  ?  7070 LEU   B H      1 
ATOM   4383 H  HA     . LEU   A  1 272 ? 57.902  -26.921 -13.397 1.00 66.37  ?  7070 LEU   B HA     1 
ATOM   4384 H  HB2    . LEU   A  1 272 ? 55.306  -27.876 -13.032 1.00 73.03  ?  7070 LEU   B HB2    1 
ATOM   4385 H  HB3    . LEU   A  1 272 ? 56.377  -28.193 -11.901 1.00 73.03  ?  7070 LEU   B HB3    1 
ATOM   4386 H  HG     . LEU   A  1 272 ? 55.782  -25.577 -12.714 1.00 84.43  ?  7070 LEU   B HG     1 
ATOM   4387 H  HD11   . LEU   A  1 272 ? 54.379  -25.280 -10.905 1.00 94.41  ?  7070 LEU   B HD11   1 
ATOM   4388 H  HD12   . LEU   A  1 272 ? 53.856  -26.546 -11.710 1.00 94.41  ?  7070 LEU   B HD12   1 
ATOM   4389 H  HD13   . LEU   A  1 272 ? 54.696  -26.744 -10.376 1.00 94.41  ?  7070 LEU   B HD13   1 
ATOM   4390 H  HD21   . LEU   A  1 272 ? 56.773  -24.956 -10.632 1.00 82.71  ?  7070 LEU   B HD21   1 
ATOM   4391 H  HD22   . LEU   A  1 272 ? 57.234  -26.468 -10.472 1.00 82.71  ?  7070 LEU   B HD22   1 
ATOM   4392 H  HD23   . LEU   A  1 272 ? 57.800  -25.586 -11.666 1.00 82.71  ?  7070 LEU   B HD23   1 
ATOM   4393 N  N      . SER   A  1 273 ? 57.337  -29.881 -14.469 1.00 56.75  ?  7071 SER   B N      1 
ATOM   4394 C  CA     . SER   A  1 273 ? 58.004  -31.155 -14.727 1.00 50.43  ?  7071 SER   B CA     1 
ATOM   4395 C  C      . SER   A  1 273 ? 59.375  -30.937 -15.348 1.00 51.53  ?  7071 SER   B C      1 
ATOM   4396 O  O      . SER   A  1 273 ? 60.377  -31.497 -14.890 1.00 51.93  ?  7071 SER   B O      1 
ATOM   4397 C  CB     . SER   A  1 273 ? 57.143  -32.019 -15.651 1.00 65.08  ?  7071 SER   B CB     1 
ATOM   4398 O  OG     . SER   A  1 273 ? 57.757  -33.268 -15.924 1.00 83.18  ?  7071 SER   B OG     1 
ATOM   4399 H  H      . SER   A  1 273 ? 56.557  -29.810 -14.825 1.00 68.62  ?  7071 SER   B H      1 
ATOM   4400 H  HA     . SER   A  1 273 ? 58.117  -31.622 -13.884 1.00 61.04  ?  7071 SER   B HA     1 
ATOM   4401 H  HB2    . SER   A  1 273 ? 56.288  -32.178 -15.221 1.00 78.62  ?  7071 SER   B HB2    1 
ATOM   4402 H  HB3    . SER   A  1 273 ? 57.011  -31.546 -16.487 1.00 78.62  ?  7071 SER   B HB3    1 
ATOM   4403 H  HG     . SER   A  1 273 ? 57.277  -33.715 -16.448 1.00 100.33 ?  7071 SER   B HG     1 
ATOM   4404 N  N      . LEU   A  1 274 ? 59.428  -30.120 -16.400 1.00 56.60  ?  7072 LEU   B N      1 
ATOM   4405 C  CA     . LEU   A  1 274 ? 60.668  -29.857 -17.122 1.00 47.55  ?  7072 LEU   B CA     1 
ATOM   4406 C  C      . LEU   A  1 274 ? 61.689  -29.147 -16.246 1.00 48.77  ?  7072 LEU   B C      1 
ATOM   4407 O  O      . LEU   A  1 274 ? 62.883  -29.468 -16.276 1.00 48.15  ?  7072 LEU   B O      1 
ATOM   4408 C  CB     . LEU   A  1 274 ? 60.334  -29.013 -18.341 1.00 54.40  ?  7072 LEU   B CB     1 
ATOM   4409 C  CG     . LEU   A  1 274 ? 59.575  -29.763 -19.431 1.00 66.80  ?  7072 LEU   B CG     1 
ATOM   4410 C  CD1    . LEU   A  1 274 ? 59.209  -28.788 -20.514 1.00 57.75  ?  7072 LEU   B CD1    1 
ATOM   4411 C  CD2    . LEU   A  1 274 ? 60.446  -30.859 -19.969 1.00 68.30  ?  7072 LEU   B CD2    1 
ATOM   4412 H  H      . LEU   A  1 274 ? 58.749  -29.700 -16.721 1.00 68.44  ?  7072 LEU   B H      1 
ATOM   4413 H  HA     . LEU   A  1 274 ? 61.067  -30.694 -17.405 1.00 57.58  ?  7072 LEU   B HA     1 
ATOM   4414 H  HB2    . LEU   A  1 274 ? 59.784  -28.266 -18.059 1.00 65.80  ?  7072 LEU   B HB2    1 
ATOM   4415 H  HB3    . LEU   A  1 274 ? 61.162  -28.688 -18.729 1.00 65.80  ?  7072 LEU   B HB3    1 
ATOM   4416 H  HG     . LEU   A  1 274 ? 58.762  -30.165 -19.085 1.00 80.68  ?  7072 LEU   B HG     1 
ATOM   4417 H  HD11   . LEU   A  1 274 ? 58.716  -29.255 -21.207 1.00 69.82  ?  7072 LEU   B HD11   1 
ATOM   4418 H  HD12   . LEU   A  1 274 ? 58.658  -28.085 -20.133 1.00 69.82  ?  7072 LEU   B HD12   1 
ATOM   4419 H  HD13   . LEU   A  1 274 ? 60.020  -28.407 -20.884 1.00 69.82  ?  7072 LEU   B HD13   1 
ATOM   4420 H  HD21   . LEU   A  1 274 ? 60.089  -31.158 -20.820 1.00 82.48  ?  7072 LEU   B HD21   1 
ATOM   4421 H  HD22   . LEU   A  1 274 ? 61.346  -30.517 -20.090 1.00 82.48  ?  7072 LEU   B HD22   1 
ATOM   4422 H  HD23   . LEU   A  1 274 ? 60.455  -31.595 -19.337 1.00 82.48  ?  7072 LEU   B HD23   1 
ATOM   4423 N  N      . LEU   A  1 275 ? 61.245  -28.126 -15.515 1.00 45.27  ?  7073 LEU   B N      1 
ATOM   4424 C  CA     . LEU   A  1 275 ? 62.108  -27.485 -14.538 1.00 44.38  ?  7073 LEU   B CA     1 
ATOM   4425 C  C      . LEU   A  1 275 ? 62.724  -28.530 -13.619 1.00 50.08  ?  7073 LEU   B C      1 
ATOM   4426 O  O      . LEU   A  1 275 ? 63.931  -28.510 -13.353 1.00 41.83  ?  7073 LEU   B O      1 
ATOM   4427 C  CB     . LEU   A  1 275 ? 61.301  -26.483 -13.730 1.00 43.62  ?  7073 LEU   B CB     1 
ATOM   4428 C  CG     . LEU   A  1 275 ? 60.825  -25.243 -14.484 1.00 50.29  ?  7073 LEU   B CG     1 
ATOM   4429 C  CD1    . LEU   A  1 275 ? 59.989  -24.367 -13.581 1.00 45.76  ?  7073 LEU   B CD1    1 
ATOM   4430 C  CD2    . LEU   A  1 275 ? 62.010  -24.484 -15.019 1.00 47.20  ?  7073 LEU   B CD2    1 
ATOM   4431 H  H      . LEU   A  1 275 ? 60.455  -27.790 -15.567 1.00 54.85  ?  7073 LEU   B H      1 
ATOM   4432 H  HA     . LEU   A  1 275 ? 62.821  -27.007 -14.990 1.00 53.78  ?  7073 LEU   B HA     1 
ATOM   4433 H  HB2    . LEU   A  1 275 ? 60.512  -26.933 -13.391 1.00 52.86  ?  7073 LEU   B HB2    1 
ATOM   4434 H  HB3    . LEU   A  1 275 ? 61.852  -26.177 -12.992 1.00 52.86  ?  7073 LEU   B HB3    1 
ATOM   4435 H  HG     . LEU   A  1 275 ? 60.270  -25.509 -15.233 1.00 60.87  ?  7073 LEU   B HG     1 
ATOM   4436 H  HD11   . LEU   A  1 275 ? 59.764  -23.550 -14.053 1.00 55.43  ?  7073 LEU   B HD11   1 
ATOM   4437 H  HD12   . LEU   A  1 275 ? 59.180  -24.843 -13.339 1.00 55.43  ?  7073 LEU   B HD12   1 
ATOM   4438 H  HD13   . LEU   A  1 275 ? 60.500  -24.157 -12.783 1.00 55.43  ?  7073 LEU   B HD13   1 
ATOM   4439 H  HD21   . LEU   A  1 275 ? 61.718  -23.606 -15.310 1.00 57.16  ?  7073 LEU   B HD21   1 
ATOM   4440 H  HD22   . LEU   A  1 275 ? 62.673  -24.396 -14.315 1.00 57.16  ?  7073 LEU   B HD22   1 
ATOM   4441 H  HD23   . LEU   A  1 275 ? 62.386  -24.973 -15.768 1.00 57.16  ?  7073 LEU   B HD23   1 
ATOM   4442 N  N      . SER   A  1 276 ? 61.901  -29.467 -13.133 1.00 47.30  ?  7074 SER   B N      1 
ATOM   4443 C  CA     . SER   A  1 276 ? 62.344  -30.429 -12.138 1.00 41.68  ?  7074 SER   B CA     1 
ATOM   4444 C  C      . SER   A  1 276 ? 63.394  -31.387 -12.683 1.00 44.73  ?  7074 SER   B C      1 
ATOM   4445 O  O      . SER   A  1 276 ? 64.128  -31.999 -11.895 1.00 44.64  ?  7074 SER   B O      1 
ATOM   4446 C  CB     . SER   A  1 276 ? 61.133  -31.200 -11.615 1.00 43.38  ?  7074 SER   B CB     1 
ATOM   4447 O  OG     . SER   A  1 276 ? 60.295  -30.320 -10.885 1.00 49.73  ?  7074 SER   B OG     1 
ATOM   4448 H  H      . SER   A  1 276 ? 61.079  -29.561 -13.368 1.00 57.28  ?  7074 SER   B H      1 
ATOM   4449 H  HA     . SER   A  1 276 ? 62.751  -29.959 -11.393 1.00 50.54  ?  7074 SER   B HA     1 
ATOM   4450 H  HB2    . SER   A  1 276 ? 60.639  -31.569 -12.363 1.00 52.57  ?  7074 SER   B HB2    1 
ATOM   4451 H  HB3    . SER   A  1 276 ? 61.435  -31.914 -11.032 1.00 52.57  ?  7074 SER   B HB3    1 
ATOM   4452 H  HG     . SER   A  1 276 ? 60.044  -29.687 -11.378 1.00 60.20  ?  7074 SER   B HG     1 
ATOM   4453 N  N      . LYS   A  1 277 ? 63.499  -31.515 -14.000 1.00 48.98  ?  7075 LYS   B N      1 
ATOM   4454 C  CA     . LYS   A  1 277 ? 64.366  -32.496 -14.632 1.00 47.91  ?  7075 LYS   B CA     1 
ATOM   4455 C  C      . LYS   A  1 277 ? 65.682  -31.896 -15.111 1.00 43.61  ?  7075 LYS   B C      1 
ATOM   4456 O  O      . LYS   A  1 277 ? 66.484  -32.614 -15.712 1.00 50.97  ?  7075 LYS   B O      1 
ATOM   4457 C  CB     . LYS   A  1 277 ? 63.633  -33.166 -15.806 1.00 55.96  ?  7075 LYS   B CB     1 
ATOM   4458 C  CG     . LYS   A  1 277 ? 62.325  -33.847 -15.399 1.00 65.49  ?  7075 LYS   B CG     1 
ATOM   4459 C  CD     . LYS   A  1 277 ? 62.163  -35.200 -16.070 1.00 75.81  ?  7075 LYS   B CD     1 
ATOM   4460 C  CE     . LYS   A  1 277 ? 60.862  -35.301 -16.832 1.00 93.30  ?  7075 LYS   B CE     1 
ATOM   4461 N  NZ     . LYS   A  1 277 ? 59.675  -35.524 -15.964 1.00 99.75  ?  7075 LYS   B NZ     1 
ATOM   4462 H  H      . LYS   A  1 277 ? 63.065  -31.031 -14.563 1.00 59.30  ?  7075 LYS   B H      1 
ATOM   4463 H  HA     . LYS   A  1 277 ? 64.578  -33.188 -13.987 1.00 58.01  ?  7075 LYS   B HA     1 
ATOM   4464 H  HB2    . LYS   A  1 277 ? 63.423  -32.490 -16.470 1.00 67.68  ?  7075 LYS   B HB2    1 
ATOM   4465 H  HB3    . LYS   A  1 277 ? 64.213  -33.841 -16.192 1.00 67.68  ?  7075 LYS   B HB3    1 
ATOM   4466 H  HG2    . LYS   A  1 277 ? 62.319  -33.981 -14.439 1.00 79.11  ?  7075 LYS   B HG2    1 
ATOM   4467 H  HG3    . LYS   A  1 277 ? 61.577  -33.286 -15.661 1.00 79.11  ?  7075 LYS   B HG3    1 
ATOM   4468 H  HD2    . LYS   A  1 277 ? 62.891  -35.336 -16.695 1.00 91.50  ?  7075 LYS   B HD2    1 
ATOM   4469 H  HD3    . LYS   A  1 277 ? 62.172  -35.895 -15.393 1.00 91.50  ?  7075 LYS   B HD3    1 
ATOM   4470 H  HE2    . LYS   A  1 277 ? 60.721  -34.474 -17.319 1.00 112.49 ?  7075 LYS   B HE2    1 
ATOM   4471 H  HE3    . LYS   A  1 277 ? 60.920  -36.045 -17.451 1.00 112.49 ?  7075 LYS   B HE3    1 
ATOM   4472 H  HZ1    . LYS   A  1 277 ? 58.940  -35.586 -16.463 1.00 120.22 ?  7075 LYS   B HZ1    1 
ATOM   4473 H  HZ2    . LYS   A  1 277 ? 59.773  -36.277 -15.500 1.00 120.22 ?  7075 LYS   B HZ2    1 
ATOM   4474 H  HZ3    . LYS   A  1 277 ? 59.581  -34.845 -15.395 1.00 120.22 ?  7075 LYS   B HZ3    1 
ATOM   4475 N  N      . GLY   A  1 278 ? 65.935  -30.616 -14.846 1.00 45.40  ?  7076 GLY   B N      1 
ATOM   4476 C  CA     . GLY   A  1 278 ? 67.123  -29.984 -15.374 1.00 49.68  ?  7076 GLY   B CA     1 
ATOM   4477 C  C      . GLY   A  1 278 ? 67.037  -29.678 -16.848 1.00 48.92  ?  7076 GLY   B C      1 
ATOM   4478 O  O      . GLY   A  1 278 ? 68.073  -29.534 -17.502 1.00 48.99  ?  7076 GLY   B O      1 
ATOM   4479 H  H      . GLY   A  1 278 ? 65.436  -30.104 -14.369 1.00 55.00  ?  7076 GLY   B H      1 
ATOM   4480 H  HA2    . GLY   A  1 278 ? 67.274  -29.151 -14.901 1.00 60.14  ?  7076 GLY   B HA2    1 
ATOM   4481 H  HA3    . GLY   A  1 278 ? 67.883  -30.570 -15.232 1.00 60.14  ?  7076 GLY   B HA3    1 
ATOM   4482 N  N      . ARG   A  1 279 ? 65.828  -29.549 -17.385 1.00 51.83  ?  7077 ARG   B N      1 
ATOM   4483 C  CA     . ARG   A  1 279 ? 65.612  -29.447 -18.811 1.00 57.36  ?  7077 ARG   B CA     1 
ATOM   4484 C  C      . ARG   A  1 279 ? 65.158  -28.048 -19.206 1.00 50.42  ?  7077 ARG   B C      1 
ATOM   4485 O  O      . ARG   A  1 279 ? 64.997  -27.783 -20.397 1.00 51.63  ?  7077 ARG   B O      1 
ATOM   4486 C  CB     . ARG   A  1 279 ? 64.587  -30.502 -19.262 1.00 56.38  ?  7077 ARG   B CB     1 
ATOM   4487 C  CG     . ARG   A  1 279 ? 65.206  -31.895 -19.486 1.00 61.72  ?  7077 ARG   B CG     1 
ATOM   4488 C  CD     . ARG   A  1 279 ? 64.510  -32.765 -20.545 1.00 90.81  ?  7077 ARG   B CD     1 
ATOM   4489 N  NE     . ARG   A  1 279 ? 63.195  -33.257 -20.147 1.00 99.69  ?  7077 ARG   B NE     1 
ATOM   4490 C  CZ     . ARG   A  1 279 ? 62.155  -33.336 -20.968 1.00 110.17 ?  7077 ARG   B CZ     1 
ATOM   4491 N  NH1    . ARG   A  1 279 ? 62.218  -32.886 -22.211 1.00 90.70  ?  7077 ARG   B NH1    1 
ATOM   4492 N  NH2    . ARG   A  1 279 ? 61.031  -33.900 -20.538 1.00 95.05  ?  7077 ARG   B NH2    1 
ATOM   4493 H  H      . ARG   A  1 279 ? 65.102  -29.518 -16.926 1.00 62.71  ?  7077 ARG   B H      1 
ATOM   4494 H  HA     . ARG   A  1 279 ? 66.435  -29.637 -19.288 1.00 69.36  ?  7077 ARG   B HA     1 
ATOM   4495 H  HB2    . ARG   A  1 279 ? 63.903  -30.586 -18.579 1.00 68.17  ?  7077 ARG   B HB2    1 
ATOM   4496 H  HB3    . ARG   A  1 279 ? 64.188  -30.215 -20.098 1.00 68.17  ?  7077 ARG   B HB3    1 
ATOM   4497 H  HG2    . ARG   A  1 279 ? 66.127  -31.779 -19.768 1.00 74.58  ?  7077 ARG   B HG2    1 
ATOM   4498 H  HG3    . ARG   A  1 279 ? 65.175  -32.382 -18.648 1.00 74.58  ?  7077 ARG   B HG3    1 
ATOM   4499 H  HD2    . ARG   A  1 279 ? 64.394  -32.239 -21.352 1.00 109.50 ?  7077 ARG   B HD2    1 
ATOM   4500 H  HD3    . ARG   A  1 279 ? 65.068  -33.537 -20.729 1.00 109.50 ?  7077 ARG   B HD3    1 
ATOM   4501 H  HE     . ARG   A  1 279 ? 63.088  -33.510 -19.332 1.00 120.15 ?  7077 ARG   B HE     1 
ATOM   4502 H  HH11   . ARG   A  1 279 ? 62.945  -32.532 -22.504 1.00 109.36 ?  7077 ARG   B HH11   1 
ATOM   4503 H  HH12   . ARG   A  1 279 ? 61.532  -32.948 -22.726 1.00 109.36 ?  7077 ARG   B HH12   1 
ATOM   4504 H  HH21   . ARG   A  1 279 ? 60.984  -34.208 -19.737 1.00 114.59 ?  7077 ARG   B HH21   1 
ATOM   4505 H  HH22   . ARG   A  1 279 ? 60.351  -33.957 -21.062 1.00 114.59 ?  7077 ARG   B HH22   1 
ATOM   4506 N  N      . LEU   A  1 280 ? 65.003  -27.129 -18.250 1.00 46.40  ?  7078 LEU   B N      1 
ATOM   4507 C  CA     . LEU   A  1 280 ? 64.435  -25.831 -18.561 1.00 46.34  ?  7078 LEU   B CA     1 
ATOM   4508 C  C      . LEU   A  1 280 ? 64.865  -24.754 -17.574 1.00 47.17  ?  7078 LEU   B C      1 
ATOM   4509 O  O      . LEU   A  1 280 ? 64.840  -24.962 -16.357 1.00 48.57  ?  7078 LEU   B O      1 
ATOM   4510 C  CB     . LEU   A  1 280 ? 62.906  -25.895 -18.581 1.00 45.42  ?  7078 LEU   B CB     1 
ATOM   4511 C  CG     . LEU   A  1 280 ? 62.193  -24.569 -18.848 1.00 48.52  ?  7078 LEU   B CG     1 
ATOM   4512 C  CD1    . LEU   A  1 280 ? 62.603  -24.093 -20.248 1.00 47.90  ?  7078 LEU   B CD1    1 
ATOM   4513 C  CD2    . LEU   A  1 280 ? 60.699  -24.696 -18.733 1.00 48.34  ?  7078 LEU   B CD2    1 
ATOM   4514 H  H      . LEU   A  1 280 ? 65.220  -27.240 -17.425 1.00 56.20  ?  7078 LEU   B H      1 
ATOM   4515 H  HA     . LEU   A  1 280 ? 64.782  -25.569 -19.428 1.00 56.13  ?  7078 LEU   B HA     1 
ATOM   4516 H  HB2    . LEU   A  1 280 ? 62.637  -26.514 -19.278 1.00 55.02  ?  7078 LEU   B HB2    1 
ATOM   4517 H  HB3    . LEU   A  1 280 ? 62.604  -26.217 -17.717 1.00 55.02  ?  7078 LEU   B HB3    1 
ATOM   4518 H  HG     . LEU   A  1 280 ? 62.451  -23.912 -18.183 1.00 58.74  ?  7078 LEU   B HG     1 
ATOM   4519 H  HD11   . LEU   A  1 280 ? 62.012  -23.375 -20.523 1.00 58.00  ?  7078 LEU   B HD11   1 
ATOM   4520 H  HD12   . LEU   A  1 280 ? 63.518  -23.775 -20.218 1.00 58.00  ?  7078 LEU   B HD12   1 
ATOM   4521 H  HD13   . LEU   A  1 280 ? 62.531  -24.837 -20.867 1.00 58.00  ?  7078 LEU   B HD13   1 
ATOM   4522 H  HD21   . LEU   A  1 280 ? 60.292  -23.840 -18.939 1.00 58.53  ?  7078 LEU   B HD21   1 
ATOM   4523 H  HD22   . LEU   A  1 280 ? 60.390  -25.369 -19.360 1.00 58.53  ?  7078 LEU   B HD22   1 
ATOM   4524 H  HD23   . LEU   A  1 280 ? 60.474  -24.960 -17.827 1.00 58.53  ?  7078 LEU   B HD23   1 
ATOM   4525 N  N      . ILE   A  1 281 ? 65.256  -23.605 -18.125 1.00 46.85  ?  7079 ILE   B N      1 
ATOM   4526 C  CA     . ILE   A  1 281 ? 65.538  -22.387 -17.373 1.00 45.52  ?  7079 ILE   B CA     1 
ATOM   4527 C  C      . ILE   A  1 281 ? 64.522  -21.333 -17.795 1.00 46.57  ?  7079 ILE   B C      1 
ATOM   4528 O  O      . ILE   A  1 281 ? 64.273  -21.150 -18.990 1.00 50.96  ?  7079 ILE   B O      1 
ATOM   4529 C  CB     . ILE   A  1 281 ? 66.975  -21.872 -17.604 1.00 45.20  ?  7079 ILE   B CB     1 
ATOM   4530 C  CG1    . ILE   A  1 281 ? 67.998  -22.752 -16.875 1.00 46.28  ?  7079 ILE   B CG1    1 
ATOM   4531 C  CG2    . ILE   A  1 281 ? 67.076  -20.405 -17.207 1.00 46.30  ?  7079 ILE   B CG2    1 
ATOM   4532 C  CD1    . ILE   A  1 281 ? 68.139  -22.489 -15.410 1.00 49.04  ?  7079 ILE   B CD1    1 
ATOM   4533 H  H      . ILE   A  1 281 ? 65.370  -23.504 -18.972 1.00 56.74  ?  7079 ILE   B H      1 
ATOM   4534 H  HA     . ILE   A  1 281 ? 65.439  -22.569 -16.425 1.00 55.14  ?  7079 ILE   B HA     1 
ATOM   4535 H  HB     . ILE   A  1 281 ? 67.183  -21.934 -18.549 1.00 54.76  ?  7079 ILE   B HB     1 
ATOM   4536 H  HG12   . ILE   A  1 281 ? 67.733  -23.679 -16.978 1.00 56.06  ?  7079 ILE   B HG12   1 
ATOM   4537 H  HG13   . ILE   A  1 281 ? 68.868  -22.609 -17.280 1.00 56.06  ?  7079 ILE   B HG13   1 
ATOM   4538 H  HG21   . ILE   A  1 281 ? 68.009  -20.177 -17.077 1.00 56.08  ?  7079 ILE   B HG21   1 
ATOM   4539 H  HG22   . ILE   A  1 281 ? 66.697  -19.860 -17.914 1.00 56.08  ?  7079 ILE   B HG22   1 
ATOM   4540 H  HG23   . ILE   A  1 281 ? 66.583  -20.267 -16.382 1.00 56.08  ?  7079 ILE   B HG23   1 
ATOM   4541 H  HD11   . ILE   A  1 281 ? 68.797  -23.098 -15.041 1.00 59.37  ?  7079 ILE   B HD11   1 
ATOM   4542 H  HD12   . ILE   A  1 281 ? 68.428  -21.572 -15.280 1.00 59.37  ?  7079 ILE   B HD12   1 
ATOM   4543 H  HD13   . ILE   A  1 281 ? 67.281  -22.629 -14.980 1.00 59.37  ?  7079 ILE   B HD13   1 
ATOM   4544 N  N      . ILE   A  1 282 ? 63.935  -20.638 -16.825 1.00 47.81  ?  7080 ILE   B N      1 
ATOM   4545 C  CA     . ILE   A  1 282 ? 63.009  -19.546 -17.118 1.00 48.67  ?  7080 ILE   B CA     1 
ATOM   4546 C  C      . ILE   A  1 282 ? 63.562  -18.243 -16.549 1.00 52.92  ?  7080 ILE   B C      1 
ATOM   4547 O  O      . ILE   A  1 282 ? 63.692  -18.091 -15.327 1.00 48.04  ?  7080 ILE   B O      1 
ATOM   4548 C  CB     . ILE   A  1 282 ? 61.595  -19.822 -16.585 1.00 46.63  ?  7080 ILE   B CB     1 
ATOM   4549 C  CG1    . ILE   A  1 282 ? 60.942  -20.934 -17.408 1.00 53.71  ?  7080 ILE   B CG1    1 
ATOM   4550 C  CG2    . ILE   A  1 282 ? 60.752  -18.554 -16.659 1.00 47.50  ?  7080 ILE   B CG2    1 
ATOM   4551 C  CD1    . ILE   A  1 282 ? 59.820  -21.628 -16.720 1.00 59.38  ?  7080 ILE   B CD1    1 
ATOM   4552 H  H      . ILE   A  1 282 ? 64.057  -20.781 -15.986 1.00 57.89  ?  7080 ILE   B H      1 
ATOM   4553 H  HA     . ILE   A  1 282 ? 62.963  -19.445 -18.081 1.00 58.93  ?  7080 ILE   B HA     1 
ATOM   4554 H  HB     . ILE   A  1 282 ? 61.657  -20.105 -15.659 1.00 56.48  ?  7080 ILE   B HB     1 
ATOM   4555 H  HG12   . ILE   A  1 282 ? 60.592  -20.549 -18.226 1.00 64.98  ?  7080 ILE   B HG12   1 
ATOM   4556 H  HG13   . ILE   A  1 282 ? 61.615  -21.601 -17.616 1.00 64.98  ?  7080 ILE   B HG13   1 
ATOM   4557 H  HG21   . ILE   A  1 282 ? 59.813  -18.796 -16.615 1.00 57.53  ?  7080 ILE   B HG21   1 
ATOM   4558 H  HG22   . ILE   A  1 282 ? 60.980  -17.979 -15.912 1.00 57.53  ?  7080 ILE   B HG22   1 
ATOM   4559 H  HG23   . ILE   A  1 282 ? 60.937  -18.100 -17.496 1.00 57.53  ?  7080 ILE   B HG23   1 
ATOM   4560 H  HD11   . ILE   A  1 282 ? 59.495  -22.343 -17.289 1.00 71.78  ?  7080 ILE   B HD11   1 
ATOM   4561 H  HD12   . ILE   A  1 282 ? 60.141  -21.992 -15.881 1.00 71.78  ?  7080 ILE   B HD12   1 
ATOM   4562 H  HD13   . ILE   A  1 282 ? 59.109  -20.989 -16.553 1.00 71.78  ?  7080 ILE   B HD13   1 
ATOM   4563 N  N      . ARG   A  1 283 ? 63.850  -17.296 -17.444 1.00 50.24  ?  7081 ARG   B N      1 
ATOM   4564 C  CA     . ARG   A  1 283 ? 64.375  -15.973 -17.124 1.00 52.03  ?  7081 ARG   B CA     1 
ATOM   4565 C  C      . ARG   A  1 283 ? 64.473  -15.203 -18.433 1.00 53.71  ?  7081 ARG   B C      1 
ATOM   4566 O  O      . ARG   A  1 283 ? 64.364  -15.784 -19.517 1.00 51.62  ?  7081 ARG   B O      1 
ATOM   4567 C  CB     . ARG   A  1 283 ? 65.734  -16.062 -16.443 1.00 48.28  ?  7081 ARG   B CB     1 
ATOM   4568 C  CG     . ARG   A  1 283 ? 66.799  -16.748 -17.267 1.00 43.57  ?  7081 ARG   B CG     1 
ATOM   4569 C  CD     . ARG   A  1 283 ? 68.214  -16.333 -16.818 1.00 41.28  ?  7081 ARG   B CD     1 
ATOM   4570 N  NE     . ARG   A  1 283 ? 69.241  -17.231 -17.339 1.00 40.15  ?  7081 ARG   B NE     1 
ATOM   4571 C  CZ     . ARG   A  1 283 ? 69.807  -17.113 -18.531 1.00 42.60  ?  7081 ARG   B CZ     1 
ATOM   4572 N  NH1    . ARG   A  1 283 ? 69.467  -16.144 -19.362 1.00 47.32  ?  7081 ARG   B NH1    1 
ATOM   4573 N  NH2    . ARG   A  1 283 ? 70.751  -17.978 -18.892 1.00 43.78  ?  7081 ARG   B NH2    1 
ATOM   4574 H  H      . ARG   A  1 283 ? 63.743  -17.405 -18.290 1.00 60.81  ?  7081 ARG   B H      1 
ATOM   4575 H  HA     . ARG   A  1 283 ? 63.766  -15.502 -16.532 1.00 62.96  ?  7081 ARG   B HA     1 
ATOM   4576 H  HB2    . ARG   A  1 283 ? 66.045  -15.163 -16.252 1.00 58.46  ?  7081 ARG   B HB2    1 
ATOM   4577 H  HB3    . ARG   A  1 283 ? 65.635  -16.561 -15.617 1.00 58.46  ?  7081 ARG   B HB3    1 
ATOM   4578 H  HG2    . ARG   A  1 283 ? 66.716  -17.709 -17.163 1.00 52.80  ?  7081 ARG   B HG2    1 
ATOM   4579 H  HG3    . ARG   A  1 283 ? 66.691  -16.505 -18.199 1.00 52.80  ?  7081 ARG   B HG3    1 
ATOM   4580 H  HD2    . ARG   A  1 283 ? 68.402  -15.438 -17.143 1.00 50.06  ?  7081 ARG   B HD2    1 
ATOM   4581 H  HD3    . ARG   A  1 283 ? 68.260  -16.351 -15.850 1.00 50.06  ?  7081 ARG   B HD3    1 
ATOM   4582 H  HE     . ARG   A  1 283 ? 69.495  -17.882 -16.838 1.00 48.70  ?  7081 ARG   B HE     1 
ATOM   4583 H  HH11   . ARG   A  1 283 ? 68.866  -15.573 -19.133 1.00 57.31  ?  7081 ARG   B HH11   1 
ATOM   4584 H  HH12   . ARG   A  1 283 ? 69.847  -16.084 -20.131 1.00 57.31  ?  7081 ARG   B HH12   1 
ATOM   4585 H  HH21   . ARG   A  1 283 ? 70.988  -18.606 -18.354 1.00 53.05  ?  7081 ARG   B HH21   1 
ATOM   4586 H  HH22   . ARG   A  1 283 ? 71.125  -17.910 -19.664 1.00 53.05  ?  7081 ARG   B HH22   1 
ATOM   4587 N  N      . GLU   A  1 284 ? 64.650  -13.885 -18.321 1.00 60.06  ?  7082 GLU   B N      1 
ATOM   4588 C  CA     . GLU   A  1 284 ? 65.083  -13.076 -19.456 1.00 52.58  ?  7082 GLU   B CA     1 
ATOM   4589 C  C      . GLU   A  1 284 ? 66.460  -13.525 -19.917 1.00 56.02  ?  7082 GLU   B C      1 
ATOM   4590 O  O      . GLU   A  1 284 ? 67.261  -14.027 -19.131 1.00 57.84  ?  7082 GLU   B O      1 
ATOM   4591 C  CB     . GLU   A  1 284 ? 65.100  -11.597 -19.069 1.00 61.64  ?  7082 GLU   B CB     1 
ATOM   4592 C  CG     . GLU   A  1 284 ? 65.741  -11.244 -17.725 1.00 80.57  ?  7082 GLU   B CG     1 
ATOM   4593 C  CD     . GLU   A  1 284 ? 67.248  -11.367 -17.626 1.00 77.29  ?  7082 GLU   B CD     1 
ATOM   4594 O  OE1    . GLU   A  1 284 ? 67.970  -10.896 -18.518 1.00 67.15  ?  7082 GLU   B OE1    1 
ATOM   4595 O  OE2    . GLU   A  1 284 ? 67.737  -11.940 -16.636 1.00 63.38  ?  7082 GLU   B OE2    1 
ATOM   4596 H  H      . GLU   A  1 284 ? 64.526  -13.436 -17.598 1.00 72.59  ?  7082 GLU   B H      1 
ATOM   4597 H  HA     . GLU   A  1 284 ? 64.466  -13.181 -20.198 1.00 63.61  ?  7082 GLU   B HA     1 
ATOM   4598 H  HB2    . GLU   A  1 284 ? 65.589  -11.114 -19.752 1.00 74.49  ?  7082 GLU   B HB2    1 
ATOM   4599 H  HB3    . GLU   A  1 284 ? 64.182  -11.286 -19.035 1.00 74.49  ?  7082 GLU   B HB3    1 
ATOM   4600 H  HG2    . GLU   A  1 284 ? 65.520  -10.322 -17.522 1.00 97.21  ?  7082 GLU   B HG2    1 
ATOM   4601 H  HG3    . GLU   A  1 284 ? 65.366  -11.832 -17.051 1.00 97.21  ?  7082 GLU   B HG3    1 
ATOM   4602 N  N      . ASN   A  1 285 ? 66.744  -13.347 -21.202 1.00 57.54  ?  7083 ASN   B N      1 
ATOM   4603 C  CA     . ASN   A  1 285 ? 68.087  -13.610 -21.706 1.00 58.12  ?  7083 ASN   B CA     1 
ATOM   4604 C  C      . ASN   A  1 285 ? 68.764  -12.314 -22.132 1.00 59.35  ?  7083 ASN   B C      1 
ATOM   4605 O  O      . ASN   A  1 285 ? 69.475  -12.265 -23.136 1.00 60.89  ?  7083 ASN   B O      1 
ATOM   4606 C  CB     . ASN   A  1 285 ? 68.067  -14.578 -22.882 1.00 65.10  ?  7083 ASN   B CB     1 
ATOM   4607 C  CG     . ASN   A  1 285 ? 69.404  -15.259 -23.092 1.00 65.36  ?  7083 ASN   B CG     1 
ATOM   4608 O  OD1    . ASN   A  1 285 ? 70.165  -15.440 -22.147 1.00 67.38  ?  7083 ASN   B OD1    1 
ATOM   4609 N  ND2    . ASN   A  1 285 ? 69.715  -15.606 -24.334 1.00 77.55  ?  7083 ASN   B ND2    1 
ATOM   4610 H  H      . ASN   A  1 285 ? 66.181  -13.078 -21.794 1.00 69.57  ?  7083 ASN   B H      1 
ATOM   4611 H  HA     . ASN   A  1 285 ? 68.598  -14.022 -20.992 1.00 70.26  ?  7083 ASN   B HA     1 
ATOM   4612 H  HB2    . ASN   A  1 285 ? 67.401  -15.264 -22.718 1.00 78.65  ?  7083 ASN   B HB2    1 
ATOM   4613 H  HB3    . ASN   A  1 285 ? 67.847  -14.090 -23.691 1.00 78.65  ?  7083 ASN   B HB3    1 
ATOM   4614 H  HD21   . ASN   A  1 285 ? 70.465  -15.995 -24.497 1.00 93.58  ?  7083 ASN   B HD21   1 
ATOM   4615 H  HD22   . ASN   A  1 285 ? 69.168  -15.441 -24.977 1.00 93.58  ?  7083 ASN   B HD22   1 
ATOM   4616 N  N      . ASN   A  1 286 ? 68.533  -11.248 -21.377 1.00 64.20  ?  7084 ASN   B N      1 
ATOM   4617 C  CA     . ASN   A  1 286 ? 69.083  -9.945  -21.718 1.00 69.57  ?  7084 ASN   B CA     1 
ATOM   4618 C  C      . ASN   A  1 286 ? 70.578  -9.928  -21.405 1.00 69.84  ?  7084 ASN   B C      1 
ATOM   4619 O  O      . ASN   A  1 286 ? 71.211  -10.963 -21.176 1.00 63.85  ?  7084 ASN   B O      1 
ATOM   4620 C  CB     . ASN   A  1 286 ? 68.326  -8.843  -20.976 1.00 69.50  ?  7084 ASN   B CB     1 
ATOM   4621 C  CG     . ASN   A  1 286 ? 66.853  -8.780  -21.364 1.00 76.16  ?  7084 ASN   B CG     1 
ATOM   4622 O  OD1    . ASN   A  1 286 ? 66.484  -9.042  -22.507 1.00 70.36  ?  7084 ASN   B OD1    1 
ATOM   4623 N  ND2    . ASN   A  1 286 ? 66.015  -8.384  -20.423 1.00 70.83  ?  7084 ASN   B ND2    1 
ATOM   4624 H  H      . ASN   A  1 286 ? 68.059  -11.254 -20.660 1.00 77.56  ?  7084 ASN   B H      1 
ATOM   4625 H  HA     . ASN   A  1 286 ? 68.968  -9.804  -22.671 1.00 84.01  ?  7084 ASN   B HA     1 
ATOM   4626 H  HB2    . ASN   A  1 286 ? 68.378  -9.010  -20.022 1.00 83.93  ?  7084 ASN   B HB2    1 
ATOM   4627 H  HB3    . ASN   A  1 286 ? 68.728  -7.986  -21.186 1.00 83.93  ?  7084 ASN   B HB3    1 
ATOM   4628 H  HD21   . ASN   A  1 286 ? 65.173  -8.332  -20.591 1.00 85.52  ?  7084 ASN   B HD21   1 
ATOM   4629 H  HD22   . ASN   A  1 286 ? 66.311  -8.178  -19.642 1.00 85.52  ?  7084 ASN   B HD22   1 
ATOM   4630 N  N      . ARG   A  1 287 ? 71.169  -8.741  -21.422 1.00 67.66  ?  7085 ARG   B N      1 
ATOM   4631 C  CA     . ARG   A  1 287 ? 72.549  -8.582  -21.009 1.00 64.45  ?  7085 ARG   B CA     1 
ATOM   4632 C  C      . ARG   A  1 287 ? 72.646  -8.548  -19.490 1.00 55.83  ?  7085 ARG   B C      1 
ATOM   4633 O  O      . ARG   A  1 287 ? 71.653  -8.347  -18.782 1.00 57.58  ?  7085 ARG   B O      1 
ATOM   4634 C  CB     . ARG   A  1 287 ? 73.141  -7.315  -21.631 1.00 61.16  ?  7085 ARG   B CB     1 
ATOM   4635 C  CG     . ARG   A  1 287 ? 72.465  -6.053  -21.173 1.00 71.82  ?  7085 ARG   B CG     1 
ATOM   4636 C  CD     . ARG   A  1 287 ? 72.325  -4.982  -22.235 1.00 75.49  ?  7085 ARG   B CD     1 
ATOM   4637 N  NE     . ARG   A  1 287 ? 72.098  -3.727  -21.537 1.00 86.96  ?  7085 ARG   B NE     1 
ATOM   4638 C  CZ     . ARG   A  1 287 ? 73.052  -2.895  -21.149 1.00 86.90  ?  7085 ARG   B CZ     1 
ATOM   4639 N  NH1    . ARG   A  1 287 ? 74.280  -2.982  -21.627 1.00 80.52  ?  7085 ARG   B NH1    1 
ATOM   4640 N  NH2    . ARG   A  1 287 ? 72.762  -1.949  -20.261 1.00 83.92  ?  7085 ARG   B NH2    1 
ATOM   4641 H  H      . ARG   A  1 287 ? 70.788  -8.010  -21.670 1.00 81.72  ?  7085 ARG   B H      1 
ATOM   4642 H  HA     . ARG   A  1 287 ? 73.080  -9.334  -21.316 1.00 77.86  ?  7085 ARG   B HA     1 
ATOM   4643 H  HB2    . ARG   A  1 287 ? 74.079  -7.255  -21.388 1.00 73.92  ?  7085 ARG   B HB2    1 
ATOM   4644 H  HB3    . ARG   A  1 287 ? 73.051  -7.367  -22.595 1.00 73.92  ?  7085 ARG   B HB3    1 
ATOM   4645 H  HG2    . ARG   A  1 287 ? 71.573  -6.276  -20.865 1.00 86.70  ?  7085 ARG   B HG2    1 
ATOM   4646 H  HG3    . ARG   A  1 287 ? 72.982  -5.673  -20.445 1.00 86.70  ?  7085 ARG   B HG3    1 
ATOM   4647 H  HD2    . ARG   A  1 287 ? 73.136  -4.918  -22.762 1.00 91.11  ?  7085 ARG   B HD2    1 
ATOM   4648 H  HD3    . ARG   A  1 287 ? 71.569  -5.173  -22.812 1.00 91.11  ?  7085 ARG   B HD3    1 
ATOM   4649 H  HE     . ARG   A  1 287 ? 71.284  -3.510  -21.362 1.00 104.88 ?  7085 ARG   B HE     1 
ATOM   4650 H  HH11   . ARG   A  1 287 ? 74.476  -3.590  -22.203 1.00 97.15  ?  7085 ARG   B HH11   1 
ATOM   4651 H  HH12   . ARG   A  1 287 ? 74.885  -2.431  -21.361 1.00 97.15  ?  7085 ARG   B HH12   1 
ATOM   4652 H  HH21   . ARG   A  1 287 ? 71.964  -1.885  -19.946 1.00 101.23 ?  7085 ARG   B HH21   1 
ATOM   4653 H  HH22   . ARG   A  1 287 ? 73.372  -1.402  -20.000 1.00 101.23 ?  7085 ARG   B HH22   1 
ATOM   4654 N  N      . VAL   A  1 288 ? 73.860  -8.766  -18.989 1.00 54.46  ?  7086 VAL   B N      1 
ATOM   4655 C  CA     . VAL   A  1 288 ? 74.089  -8.990  -17.569 1.00 45.03  ?  7086 VAL   B CA     1 
ATOM   4656 C  C      . VAL   A  1 288 ? 74.735  -7.730  -17.016 1.00 42.87  ?  7086 VAL   B C      1 
ATOM   4657 O  O      . VAL   A  1 288 ? 75.814  -7.323  -17.467 1.00 46.60  ?  7086 VAL   B O      1 
ATOM   4658 C  CB     . VAL   A  1 288 ? 74.959  -10.229 -17.328 1.00 49.59  ?  7086 VAL   B CB     1 
ATOM   4659 C  CG1    . VAL   A  1 288 ? 75.376  -10.306 -15.874 1.00 53.14  ?  7086 VAL   B CG1    1 
ATOM   4660 C  CG2    . VAL   A  1 288 ? 74.190  -11.471 -17.757 1.00 58.29  ?  7086 VAL   B CG2    1 
ATOM   4661 H  H      . VAL   A  1 288 ? 74.578  -8.788  -19.462 1.00 65.88  ?  7086 VAL   B H      1 
ATOM   4662 H  HA     . VAL   A  1 288 ? 73.246  -9.132  -17.111 1.00 54.56  ?  7086 VAL   B HA     1 
ATOM   4663 H  HB     . VAL   A  1 288 ? 75.771  -10.175 -17.856 1.00 60.04  ?  7086 VAL   B HB     1 
ATOM   4664 H  HG11   . VAL   A  1 288 ? 75.685  -11.206 -15.682 1.00 64.29  ?  7086 VAL   B HG11   1 
ATOM   4665 H  HG12   . VAL   A  1 288 ? 76.091  -9.670  -15.717 1.00 64.29  ?  7086 VAL   B HG12   1 
ATOM   4666 H  HG13   . VAL   A  1 288 ? 74.614  -10.092 -15.315 1.00 64.29  ?  7086 VAL   B HG13   1 
ATOM   4667 H  HG21   . VAL   A  1 288 ? 74.606  -12.252 -17.360 1.00 70.47  ?  7086 VAL   B HG21   1 
ATOM   4668 H  HG22   . VAL   A  1 288 ? 73.272  -11.395 -17.453 1.00 70.47  ?  7086 VAL   B HG22   1 
ATOM   4669 H  HG23   . VAL   A  1 288 ? 74.214  -11.538 -18.724 1.00 70.47  ?  7086 VAL   B HG23   1 
ATOM   4670 N  N      . VAL   A  1 289 ? 74.052  -7.099  -16.067 1.00 37.94  ?  7087 VAL   B N      1 
ATOM   4671 C  CA     . VAL   A  1 289 ? 74.449  -5.819  -15.515 1.00 43.31  ?  7087 VAL   B CA     1 
ATOM   4672 C  C      . VAL   A  1 289 ? 74.380  -5.935  -14.000 1.00 37.29  ?  7087 VAL   B C      1 
ATOM   4673 O  O      . VAL   A  1 289 ? 73.383  -6.421  -13.458 1.00 43.65  ?  7087 VAL   B O      1 
ATOM   4674 C  CB     . VAL   A  1 289 ? 73.549  -4.673  -16.019 1.00 40.42  ?  7087 VAL   B CB     1 
ATOM   4675 C  CG1    . VAL   A  1 289 ? 73.873  -3.397  -15.257 1.00 40.06  ?  7087 VAL   B CG1    1 
ATOM   4676 C  CG2    . VAL   A  1 289 ? 73.722  -4.508  -17.520 1.00 48.38  ?  7087 VAL   B CG2    1 
ATOM   4677 H  H      . VAL   A  1 289 ? 73.330  -7.408  -15.717 1.00 46.05  ?  7087 VAL   B H      1 
ATOM   4678 H  HA     . VAL   A  1 289 ? 75.362  -5.615  -15.773 1.00 52.49  ?  7087 VAL   B HA     1 
ATOM   4679 H  HB     . VAL   A  1 289 ? 72.615  -4.877  -15.858 1.00 49.03  ?  7087 VAL   B HB     1 
ATOM   4680 H  HG11   . VAL   A  1 289 ? 73.509  -2.639  -15.740 1.00 48.59  ?  7087 VAL   B HG11   1 
ATOM   4681 H  HG12   . VAL   A  1 289 ? 73.476  -3.447  -14.373 1.00 48.59  ?  7087 VAL   B HG12   1 
ATOM   4682 H  HG13   . VAL   A  1 289 ? 74.836  -3.310  -15.182 1.00 48.59  ?  7087 VAL   B HG13   1 
ATOM   4683 H  HG21   . VAL   A  1 289 ? 73.150  -3.786  -17.826 1.00 58.58  ?  7087 VAL   B HG21   1 
ATOM   4684 H  HG22   . VAL   A  1 289 ? 74.649  -4.298  -17.710 1.00 58.58  ?  7087 VAL   B HG22   1 
ATOM   4685 H  HG23   . VAL   A  1 289 ? 73.473  -5.336  -17.960 1.00 58.58  ?  7087 VAL   B HG23   1 
ATOM   4686 N  N      . ILE   A  1 290 ? 75.440  -5.511  -13.323 1.00 41.48  ?  7088 ILE   B N      1 
ATOM   4687 C  CA     . ILE   A  1 290 ? 75.559  -5.664  -11.884 1.00 45.46  ?  7088 ILE   B CA     1 
ATOM   4688 C  C      . ILE   A  1 290 ? 76.034  -4.336  -11.325 1.00 40.65  ?  7088 ILE   B C      1 
ATOM   4689 O  O      . ILE   A  1 290 ? 76.544  -3.479  -12.046 1.00 43.88  ?  7088 ILE   B O      1 
ATOM   4690 C  CB     . ILE   A  1 290 ? 76.515  -6.814  -11.514 1.00 37.04  ?  7088 ILE   B CB     1 
ATOM   4691 C  CG1    . ILE   A  1 290 ? 77.916  -6.525  -12.037 1.00 44.01  ?  7088 ILE   B CG1    1 
ATOM   4692 C  CG2    . ILE   A  1 290 ? 76.016  -8.111  -12.117 1.00 42.94  ?  7088 ILE   B CG2    1 
ATOM   4693 C  CD1    . ILE   A  1 290 ? 78.956  -7.519  -11.620 1.00 41.24  ?  7088 ILE   B CD1    1 
ATOM   4694 H  H      . ILE   A  1 290 ? 76.117  -5.124  -13.685 1.00 50.29  ?  7088 ILE   B H      1 
ATOM   4695 H  HA     . ILE   A  1 290 ? 74.699  -5.865  -11.483 1.00 55.07  ?  7088 ILE   B HA     1 
ATOM   4696 H  HB     . ILE   A  1 290 ? 76.544  -6.891  -10.547 1.00 44.97  ?  7088 ILE   B HB     1 
ATOM   4697 H  HG12   . ILE   A  1 290 ? 77.888  -6.520  -13.007 1.00 53.33  ?  7088 ILE   B HG12   1 
ATOM   4698 H  HG13   . ILE   A  1 290 ? 78.194  -5.655  -11.709 1.00 53.33  ?  7088 ILE   B HG13   1 
ATOM   4699 H  HG21   . ILE   A  1 290 ? 76.504  -8.851  -11.724 1.00 52.05  ?  7088 ILE   B HG21   1 
ATOM   4700 H  HG22   . ILE   A  1 290 ? 75.068  -8.202  -11.930 1.00 52.05  ?  7088 ILE   B HG22   1 
ATOM   4701 H  HG23   . ILE   A  1 290 ? 76.163  -8.090  -13.076 1.00 52.05  ?  7088 ILE   B HG23   1 
ATOM   4702 H  HD11   . ILE   A  1 290 ? 79.834  -7.165  -11.832 1.00 50.00  ?  7088 ILE   B HD11   1 
ATOM   4703 H  HD12   . ILE   A  1 290 ? 78.883  -7.672  -10.665 1.00 50.00  ?  7088 ILE   B HD12   1 
ATOM   4704 H  HD13   . ILE   A  1 290 ? 78.810  -8.349  -12.100 1.00 50.00  ?  7088 ILE   B HD13   1 
ATOM   4705 N  N      . SER   A  1 291 ? 75.832  -4.155  -10.031 1.00 45.87  ?  7089 SER   B N      1 
ATOM   4706 C  CA     . SER   A  1 291 ? 76.313  -2.941  -9.403  1.00 41.01  ?  7089 SER   B CA     1 
ATOM   4707 C  C      . SER   A  1 291 ? 76.547  -3.192  -7.922  1.00 45.39  ?  7089 SER   B C      1 
ATOM   4708 O  O      . SER   A  1 291 ? 75.998  -4.123  -7.326  1.00 43.93  ?  7089 SER   B O      1 
ATOM   4709 C  CB     . SER   A  1 291 ? 75.346  -1.769  -9.613  1.00 42.70  ?  7089 SER   B CB     1 
ATOM   4710 O  OG     . SER   A  1 291 ? 74.114  -1.963  -8.949  1.00 49.23  ?  7089 SER   B OG     1 
ATOM   4711 H  H      . SER   A  1 291 ? 75.429  -4.707  -9.509  1.00 55.56  ?  7089 SER   B H      1 
ATOM   4712 H  HA     . SER   A  1 291 ? 77.166  -2.700  -9.797  1.00 49.73  ?  7089 SER   B HA     1 
ATOM   4713 H  HB2    . SER   A  1 291 ? 75.759  -0.961  -9.270  1.00 51.76  ?  7089 SER   B HB2    1 
ATOM   4714 H  HB3    . SER   A  1 291 ? 75.174  -1.676  -10.563 1.00 51.76  ?  7089 SER   B HB3    1 
ATOM   4715 H  HG     . SER   A  1 291 ? 73.761  -2.682  -9.201  1.00 59.60  ?  7089 SER   B HG     1 
ATOM   4716 N  N      . SER   A  1 292 ? 77.416  -2.364  -7.355  1.00 44.78  ?  7090 SER   B N      1 
ATOM   4717 C  CA     . SER   A  1 292 ? 77.756  -2.395  -5.943  1.00 48.40  ?  7090 SER   B CA     1 
ATOM   4718 C  C      . SER   A  1 292 ? 77.414  -1.034  -5.353  1.00 46.32  ?  7090 SER   B C      1 
ATOM   4719 O  O      . SER   A  1 292 ? 77.937  -0.009  -5.805  1.00 45.73  ?  7090 SER   B O      1 
ATOM   4720 C  CB     . SER   A  1 292 ? 79.247  -2.721  -5.771  1.00 48.30  ?  7090 SER   B CB     1 
ATOM   4721 O  OG     . SER   A  1 292 ? 79.502  -3.307  -4.511  1.00 61.26  ?  7090 SER   B OG     1 
ATOM   4722 H  H      . SER   A  1 292 ? 77.837  -1.751  -7.787  1.00 54.25  ?  7090 SER   B H      1 
ATOM   4723 H  HA     . SER   A  1 292 ? 77.241  -3.069  -5.472  1.00 58.60  ?  7090 SER   B HA     1 
ATOM   4724 H  HB2    . SER   A  1 292 ? 79.515  -3.341  -6.467  1.00 58.48  ?  7090 SER   B HB2    1 
ATOM   4725 H  HB3    . SER   A  1 292 ? 79.758  -1.899  -5.845  1.00 58.48  ?  7090 SER   B HB3    1 
ATOM   4726 H  HG     . SER   A  1 292 ? 79.253  -2.790  -3.898  1.00 74.04  ?  7090 SER   B HG     1 
ATOM   4727 N  N      . ASP   A  1 293 ? 76.503  -1.012  -4.387  1.00 46.18  ?  7091 ASP   B N      1 
ATOM   4728 C  CA     . ASP   A  1 293 ? 76.116  0.252   -3.768  1.00 47.64  ?  7091 ASP   B CA     1 
ATOM   4729 C  C      . ASP   A  1 293 ? 77.268  0.801   -2.923  1.00 50.57  ?  7091 ASP   B C      1 
ATOM   4730 O  O      . ASP   A  1 293 ? 77.933  0.063   -2.185  1.00 54.65  ?  7091 ASP   B O      1 
ATOM   4731 C  CB     . ASP   A  1 293 ? 74.868  0.071   -2.896  1.00 43.64  ?  7091 ASP   B CB     1 
ATOM   4732 C  CG     . ASP   A  1 293 ? 73.572  0.009   -3.696  1.00 47.42  ?  7091 ASP   B CG     1 
ATOM   4733 O  OD1    . ASP   A  1 293 ? 73.608  0.098   -4.928  1.00 57.30  ?  7091 ASP   B OD1    1 
ATOM   4734 O  OD2    . ASP   A  1 293 ? 72.497  -0.105  -3.070  1.00 59.99  ?  7091 ASP   B OD2    1 
ATOM   4735 H  H      . ASP   A  1 293 ? 76.098  -1.705  -4.076  1.00 55.93  ?  7091 ASP   B H      1 
ATOM   4736 H  HA     . ASP   A  1 293 ? 75.904  0.896   -4.461  1.00 57.69  ?  7091 ASP   B HA     1 
ATOM   4737 H  HB2    . ASP   A  1 293 ? 74.951  -0.758  -2.400  1.00 52.90  ?  7091 ASP   B HB2    1 
ATOM   4738 H  HB3    . ASP   A  1 293 ? 74.803  0.820   -2.283  1.00 52.90  ?  7091 ASP   B HB3    1 
ATOM   4739 N  N      . VAL   A  1 294 ? 77.512  2.102   -3.039  1.00 50.25  ?  7092 VAL   B N      1 
ATOM   4740 C  CA     . VAL   A  1 294 ? 78.633  2.761   -2.376  1.00 47.39  ?  7092 VAL   B CA     1 
ATOM   4741 C  C      . VAL   A  1 294 ? 78.111  3.834   -1.440  1.00 45.62  ?  7092 VAL   B C      1 
ATOM   4742 O  O      . VAL   A  1 294 ? 77.369  4.729   -1.863  1.00 43.68  ?  7092 VAL   B O      1 
ATOM   4743 C  CB     . VAL   A  1 294 ? 79.619  3.387   -3.378  1.00 48.35  ?  7092 VAL   B CB     1 
ATOM   4744 C  CG1    . VAL   A  1 294 ? 80.731  4.145   -2.642  1.00 45.33  ?  7092 VAL   B CG1    1 
ATOM   4745 C  CG2    . VAL   A  1 294 ? 80.235  2.306   -4.261  1.00 48.77  ?  7092 VAL   B CG2    1 
ATOM   4746 H  H      . VAL   A  1 294 ? 77.029  2.638   -3.508  1.00 60.82  ?  7092 VAL   B H      1 
ATOM   4747 H  HA     . VAL   A  1 294 ? 79.097  2.090   -1.851  1.00 57.39  ?  7092 VAL   B HA     1 
ATOM   4748 H  HB     . VAL   A  1 294 ? 79.133  4.014   -3.937  1.00 58.54  ?  7092 VAL   B HB     1 
ATOM   4749 H  HG11   . VAL   A  1 294 ? 81.467  4.300   -3.255  1.00 54.92  ?  7092 VAL   B HG11   1 
ATOM   4750 H  HG12   . VAL   A  1 294 ? 80.380  4.992   -2.326  1.00 54.92  ?  7092 VAL   B HG12   1 
ATOM   4751 H  HG13   . VAL   A  1 294 ? 81.033  3.611   -1.890  1.00 54.92  ?  7092 VAL   B HG13   1 
ATOM   4752 H  HG21   . VAL   A  1 294 ? 80.869  2.718   -4.869  1.00 59.05  ?  7092 VAL   B HG21   1 
ATOM   4753 H  HG22   . VAL   A  1 294 ? 80.689  1.660   -3.698  1.00 59.05  ?  7092 VAL   B HG22   1 
ATOM   4754 H  HG23   . VAL   A  1 294 ? 79.530  1.869   -4.764  1.00 59.05  ?  7092 VAL   B HG23   1 
ATOM   4755 N  N      . LEU   A  1 295 ? 78.555  3.773   -0.188  1.00 46.78  ?  7093 LEU   B N      1 
ATOM   4756 C  CA     . LEU   A  1 295 ? 78.181  4.741   0.823   1.00 44.97  ?  7093 LEU   B CA     1 
ATOM   4757 C  C      . LEU   A  1 295 ? 79.164  5.907   0.792   1.00 46.38  ?  7093 LEU   B C      1 
ATOM   4758 O  O      . LEU   A  1 295 ? 80.374  5.708   0.943   1.00 54.69  ?  7093 LEU   B O      1 
ATOM   4759 C  CB     . LEU   A  1 295 ? 78.155  4.100   2.204   1.00 50.91  ?  7093 LEU   B CB     1 
ATOM   4760 C  CG     . LEU   A  1 295 ? 77.885  5.115   3.313   1.00 55.22  ?  7093 LEU   B CG     1 
ATOM   4761 C  CD1    . LEU   A  1 295 ? 76.497  5.696   3.143   1.00 58.08  ?  7093 LEU   B CD1    1 
ATOM   4762 C  CD2    . LEU   A  1 295 ? 78.042  4.441   4.679   1.00 52.85  ?  7093 LEU   B CD2    1 
ATOM   4763 H  H      . LEU   A  1 295 ? 79.088  3.163   0.102   1.00 56.66  ?  7093 LEU   B H      1 
ATOM   4764 H  HA     . LEU   A  1 295 ? 77.293  5.081   0.630   1.00 54.48  ?  7093 LEU   B HA     1 
ATOM   4765 H  HB2    . LEU   A  1 295 ? 77.454  3.430   2.228   1.00 61.62  ?  7093 LEU   B HB2    1 
ATOM   4766 H  HB3    . LEU   A  1 295 ? 79.015  3.685   2.376   1.00 61.62  ?  7093 LEU   B HB3    1 
ATOM   4767 H  HG     . LEU   A  1 295 ? 78.522  5.845   3.267   1.00 66.79  ?  7093 LEU   B HG     1 
ATOM   4768 H  HD11   . LEU   A  1 295 ? 76.255  6.177   3.950   1.00 70.22  ?  7093 LEU   B HD11   1 
ATOM   4769 H  HD12   . LEU   A  1 295 ? 76.499  6.300   2.385   1.00 70.22  ?  7093 LEU   B HD12   1 
ATOM   4770 H  HD13   . LEU   A  1 295 ? 75.869  4.973   2.989   1.00 70.22  ?  7093 LEU   B HD13   1 
ATOM   4771 H  HD21   . LEU   A  1 295 ? 77.866  5.093   5.375   1.00 63.94  ?  7093 LEU   B HD21   1 
ATOM   4772 H  HD22   . LEU   A  1 295 ? 77.410  3.708   4.744   1.00 63.94  ?  7093 LEU   B HD22   1 
ATOM   4773 H  HD23   . LEU   A  1 295 ? 78.948  4.104   4.763   1.00 63.94  ?  7093 LEU   B HD23   1 
ATOM   4774 N  N      . VAL   A  1 296 ? 78.642  7.125   0.615   1.00 49.78  ?  7094 VAL   B N      1 
ATOM   4775 C  CA     . VAL   A  1 296 ? 79.463  8.314   0.434   1.00 48.81  ?  7094 VAL   B CA     1 
ATOM   4776 C  C      . VAL   A  1 296 ? 79.513  9.079   1.748   1.00 52.36  ?  7094 VAL   B C      1 
ATOM   4777 O  O      . VAL   A  1 296 ? 78.472  9.358   2.362   1.00 49.89  ?  7094 VAL   B O      1 
ATOM   4778 C  CB     . VAL   A  1 296 ? 78.919  9.200   -0.697  1.00 49.26  ?  7094 VAL   B CB     1 
ATOM   4779 C  CG1    . VAL   A  1 296 ? 79.878  10.319  -0.990  1.00 47.66  ?  7094 VAL   B CG1    1 
ATOM   4780 C  CG2    . VAL   A  1 296 ? 78.654  8.357   -1.938  1.00 48.50  ?  7094 VAL   B CG2    1 
ATOM   4781 H  H      . VAL   A  1 296 ? 77.797  7.285   0.597   1.00 60.25  ?  7094 VAL   B H      1 
ATOM   4782 H  HA     . VAL   A  1 296 ? 80.366  8.044   0.204   1.00 59.10  ?  7094 VAL   B HA     1 
ATOM   4783 H  HB     . VAL   A  1 296 ? 78.079  9.600   -0.423  1.00 59.63  ?  7094 VAL   B HB     1 
ATOM   4784 H  HG11   . VAL   A  1 296 ? 79.597  10.772  -1.801  1.00 57.71  ?  7094 VAL   B HG11   1 
ATOM   4785 H  HG12   . VAL   A  1 296 ? 79.875  10.941  -0.246  1.00 57.71  ?  7094 VAL   B HG12   1 
ATOM   4786 H  HG13   . VAL   A  1 296 ? 80.767  9.950   -1.109  1.00 57.71  ?  7094 VAL   B HG13   1 
ATOM   4787 H  HG21   . VAL   A  1 296 ? 78.493  8.946   -2.692  1.00 58.72  ?  7094 VAL   B HG21   1 
ATOM   4788 H  HG22   . VAL   A  1 296 ? 79.428  7.800   -2.112  1.00 58.72  ?  7094 VAL   B HG22   1 
ATOM   4789 H  HG23   . VAL   A  1 296 ? 77.875  7.800   -1.781  1.00 58.72  ?  7094 VAL   B HG23   1 
ATOM   4790 N  N      . ASN   A  1 297 ? 80.732  9.392   2.190   1.00 61.12  ?  7095 ASN   B N      1 
ATOM   4791 C  CA     . ASN   A  1 297 ? 80.965  10.193  3.384   1.00 56.96  ?  7095 ASN   B CA     1 
ATOM   4792 C  C      . ASN   A  1 297 ? 82.131  11.145  3.148   1.00 51.66  ?  7095 ASN   B C      1 
ATOM   4793 O  O      . ASN   A  1 297 ? 83.105  10.800  2.473   1.00 55.27  ?  7095 ASN   B O      1 
ATOM   4794 C  CB     . ASN   A  1 297 ? 81.285  9.328   4.616   1.00 66.36  ?  7095 ASN   B CB     1 
ATOM   4795 C  CG     . ASN   A  1 297 ? 80.121  8.523   5.080   1.00 83.23  ?  7095 ASN   B CG     1 
ATOM   4796 O  OD1    . ASN   A  1 297 ? 79.348  8.960   5.922   1.00 86.84  ?  7095 ASN   B OD1    1 
ATOM   4797 N  ND2    . ASN   A  1 297 ? 80.005  7.321   4.569   1.00 86.77  ?  7095 ASN   B ND2    1 
ATOM   4798 H  H      . ASN   A  1 297 ? 81.458  9.143   1.802   1.00 73.87  ?  7095 ASN   B H      1 
ATOM   4799 H  HA     . ASN   A  1 297 ? 80.164  10.710  3.562   1.00 68.88  ?  7095 ASN   B HA     1 
ATOM   4800 H  HB2    . ASN   A  1 297 ? 82.003  8.714   4.393   1.00 80.15  ?  7095 ASN   B HB2    1 
ATOM   4801 H  HB3    . ASN   A  1 297 ? 81.559  9.906   5.345   1.00 80.15  ?  7095 ASN   B HB3    1 
ATOM   4802 H  HD21   . ASN   A  1 297 ? 80.584  7.039   3.999   1.00 104.64 ?  7095 ASN   B HD21   1 
ATOM   4803 H  HD22   . ASN   A  1 297 ? 79.351  6.815   4.803   1.00 104.64 ?  7095 ASN   B HD22   1 
ATOM   4804 N  N      . ASN   A  1 298 ? 82.024  12.349  3.718   1.00 58.71  ?  7096 ASN   B N      1 
ATOM   4805 C  CA     . ASN   A  1 298 ? 83.116  13.322  3.771   1.00 59.90  ?  7096 ASN   B CA     1 
ATOM   4806 C  C      . ASN   A  1 298 ? 83.503  13.487  5.239   1.00 57.68  ?  7096 ASN   B C      1 
ATOM   4807 O  O      . ASN   A  1 298 ? 82.714  14.001  6.038   1.00 57.65  ?  7096 ASN   B O      1 
ATOM   4808 C  CB     . ASN   A  1 298 ? 82.690  14.657  3.158   1.00 53.59  ?  7096 ASN   B CB     1 
ATOM   4809 C  CG     . ASN   A  1 298 ? 83.829  15.658  3.091   1.00 50.34  ?  7096 ASN   B CG     1 
ATOM   4810 O  OD1    . ASN   A  1 298 ? 84.823  15.553  3.816   1.00 55.14  ?  7096 ASN   B OD1    1 
ATOM   4811 N  ND2    . ASN   A  1 298 ? 83.687  16.643  2.219   1.00 46.05  ?  7096 ASN   B ND2    1 
ATOM   4812 H  H      . ASN   A  1 298 ? 81.304  12.633  4.093   1.00 70.98  ?  7096 ASN   B H      1 
ATOM   4813 H  HA     . ASN   A  1 298 ? 83.882  12.994  3.275   1.00 72.40  ?  7096 ASN   B HA     1 
ATOM   4814 H  HB2    . ASN   A  1 298 ? 82.371  14.503  2.255   1.00 64.83  ?  7096 ASN   B HB2    1 
ATOM   4815 H  HB3    . ASN   A  1 298 ? 81.983  15.043  3.699   1.00 64.83  ?  7096 ASN   B HB3    1 
ATOM   4816 H  HD21   . ASN   A  1 298 ? 84.302  17.239  2.139   1.00 55.78  ?  7096 ASN   B HD21   1 
ATOM   4817 H  HD22   . ASN   A  1 298 ? 82.979  16.688  1.732   1.00 55.78  ?  7096 ASN   B HD22   1 
ATOM   4818 N  N      . GLU   A  1 299 ? 84.704  13.035  5.598   1.00 70.69  ?  7097 GLU   B N      1 
ATOM   4819 C  CA     . GLU   A  1 299 ? 85.170  13.029  6.980   1.00 85.96  ?  7097 GLU   B CA     1 
ATOM   4820 C  C      . GLU   A  1 299 ? 85.983  14.266  7.328   1.00 76.78  ?  7097 GLU   B C      1 
ATOM   4821 O  O      . GLU   A  1 299 ? 86.683  14.271  8.344   1.00 70.92  ?  7097 GLU   B O      1 
ATOM   4822 C  CB     . GLU   A  1 299 ? 85.984  11.755  7.242   1.00 101.33 ?  7097 GLU   B CB     1 
ATOM   4823 C  CG     . GLU   A  1 299 ? 85.321  10.483  6.734   1.00 101.44 ?  7097 GLU   B CG     1 
ATOM   4824 C  CD     . GLU   A  1 299 ? 84.110  10.091  7.545   1.00 104.72 ?  7097 GLU   B CD     1 
ATOM   4825 O  OE1    . GLU   A  1 299 ? 83.587  10.932  8.293   1.00 101.16 ?  7097 GLU   B OE1    1 
ATOM   4826 O  OE2    . GLU   A  1 299 ? 83.672  8.934   7.438   1.00 98.76  ?  7097 GLU   B OE2    1 
ATOM   4827 H  H      . GLU   A  1 299 ? 85.279  12.720  5.042   1.00 85.35  ?  7097 GLU   B H      1 
ATOM   4828 H  HA     . GLU   A  1 299 ? 84.401  13.018  7.571   1.00 103.68 ?  7097 GLU   B HA     1 
ATOM   4829 H  HB2    . GLU   A  1 299 ? 86.842  11.837  6.799   1.00 122.11 ?  7097 GLU   B HB2    1 
ATOM   4830 H  HB3    . GLU   A  1 299 ? 86.112  11.659  8.198   1.00 122.11 ?  7097 GLU   B HB3    1 
ATOM   4831 H  HG2    . GLU   A  1 299 ? 85.036  10.620  5.817   1.00 122.25 ?  7097 GLU   B HG2    1 
ATOM   4832 H  HG3    . GLU   A  1 299 ? 85.960  9.754   6.777   1.00 122.25 ?  7097 GLU   B HG3    1 
ATOM   4833 N  N      . ASN   A  1 300 ? 85.881  15.322  6.534   1.00 66.58  ?  7098 ASN   B N      1 
ATOM   4834 C  CA     . ASN   A  1 300 ? 86.655  16.524  6.789   1.00 65.89  ?  7098 ASN   B CA     1 
ATOM   4835 C  C      . ASN   A  1 300 ? 85.924  17.474  7.740   1.00 71.18  ?  7098 ASN   B C      1 
ATOM   4836 O  O      . ASN   A  1 300 ? 84.690  17.545  7.748   1.00 66.32  ?  7098 ASN   B O      1 
ATOM   4837 C  CB     . ASN   A  1 300 ? 86.989  17.229  5.474   1.00 55.60  ?  7098 ASN   B CB     1 
ATOM   4838 C  CG     . ASN   A  1 300 ? 88.048  16.492  4.671   1.00 61.33  ?  7098 ASN   B CG     1 
ATOM   4839 O  OD1    . ASN   A  1 300 ? 87.807  16.033  3.548   1.00 68.26  ?  7098 ASN   B OD1    1 
ATOM   4840 N  ND2    . ASN   A  1 300 ? 89.217  16.311  5.277   1.00 64.06  ?  7098 ASN   B ND2    1 
ATOM   4841 H  H      . ASN   A  1 300 ? 85.370  15.366  5.844   1.00 80.41  ?  7098 ASN   B H      1 
ATOM   4842 H  HA     . ASN   A  1 300 ? 87.488  16.280  7.223   1.00 79.59  ?  7098 ASN   B HA     1 
ATOM   4843 H  HB2    . ASN   A  1 300 ? 86.186  17.287  4.933   1.00 67.25  ?  7098 ASN   B HB2    1 
ATOM   4844 H  HB3    . ASN   A  1 300 ? 87.323  18.119  5.667   1.00 67.25  ?  7098 ASN   B HB3    1 
ATOM   4845 H  HD21   . ASN   A  1 300 ? 89.853  15.900  4.870   1.00 77.40  ?  7098 ASN   B HD21   1 
ATOM   4846 H  HD22   . ASN   A  1 300 ? 89.337  16.604  6.076   1.00 77.40  ?  7098 ASN   B HD22   1 
ATOM   4847 N  N      . LEU   A  1 301 ? 86.718  18.220  8.528   1.00 77.91  ?  7099 LEU   B N      1 
ATOM   4848 C  CA     . LEU   A  1 301 ? 86.305  18.904  9.772   1.00 81.51  ?  7099 LEU   B CA     1 
ATOM   4849 C  C      . LEU   A  1 301 ? 85.284  18.044  10.526  1.00 91.04  ?  7099 LEU   B C      1 
ATOM   4850 O  O      . LEU   A  1 301 ? 85.640  17.202  11.347  1.00 82.20  ?  7099 LEU   B O      1 
ATOM   4851 C  CB     . LEU   A  1 301 ? 85.721  20.277  9.476   1.00 78.75  ?  7099 LEU   B CB     1 
ATOM   4852 C  CG     . LEU   A  1 301 ? 86.627  21.492  9.218   1.00 79.20  ?  7099 LEU   B CG     1 
ATOM   4853 C  CD1    . LEU   A  1 301 ? 85.895  22.831  9.597   1.00 69.15  ?  7099 LEU   B CD1    1 
ATOM   4854 C  CD2    . LEU   A  1 301 ? 88.001  21.485  9.866   1.00 70.28  ?  7099 LEU   B CD2    1 
ATOM   4855 H  H      . LEU   A  1 301 ? 87.549  18.355  8.355   1.00 94.01  ?  7099 LEU   B H      1 
ATOM   4856 H  HA     . LEU   A  1 301 ? 87.082  19.039  10.336  1.00 98.33  ?  7099 LEU   B HA     1 
ATOM   4857 H  HB2    . LEU   A  1 301 ? 85.171  20.184  8.683   1.00 95.02  ?  7099 LEU   B HB2    1 
ATOM   4858 H  HB3    . LEU   A  1 301 ? 85.168  20.517  10.236  1.00 95.02  ?  7099 LEU   B HB3    1 
ATOM   4859 H  HG     . LEU   A  1 301 ? 86.804  21.437  8.266   1.00 95.56  ?  7099 LEU   B HG     1 
ATOM   4860 H  HD11   . LEU   A  1 301 ? 86.482  23.578  9.402   1.00 83.50  ?  7099 LEU   B HD11   1 
ATOM   4861 H  HD12   . LEU   A  1 301 ? 85.081  22.904  9.076   1.00 83.50  ?  7099 LEU   B HD12   1 
ATOM   4862 H  HD13   . LEU   A  1 301 ? 85.682  22.817  10.544  1.00 83.50  ?  7099 LEU   B HD13   1 
ATOM   4863 H  HD21   . LEU   A  1 301 ? 88.477  22.290  9.606   1.00 84.86  ?  7099 LEU   B HD21   1 
ATOM   4864 H  HD22   . LEU   A  1 301 ? 87.896  21.459  10.830  1.00 84.86  ?  7099 LEU   B HD22   1 
ATOM   4865 H  HD23   . LEU   A  1 301 ? 88.488  20.702  9.565   1.00 84.86  ?  7099 LEU   B HD23   1 
ATOM   4866 N  N      . ALA   B  2 19  ? 108.420 11.329  -18.738 1.00 71.76  ?  4271 ALA   C N      1 
ATOM   4867 C  CA     . ALA   B  2 19  ? 107.423 11.046  -17.714 1.00 91.31  ?  4271 ALA   C CA     1 
ATOM   4868 C  C      . ALA   B  2 19  ? 107.835 9.832   -16.882 1.00 90.43  ?  4271 ALA   C C      1 
ATOM   4869 O  O      . ALA   B  2 19  ? 108.786 9.132   -17.234 1.00 79.38  ?  4271 ALA   C O      1 
ATOM   4870 C  CB     . ALA   B  2 19  ? 106.080 10.823  -18.353 1.00 77.16  ?  4271 ALA   C CB     1 
ATOM   4871 H  HA     . ALA   B  2 19  ? 107.349 11.805  -17.116 1.00 110.09 ?  4271 ALA   C HA     1 
ATOM   4872 H  HB1    . ALA   B  2 19  ? 105.425 10.649  -17.659 1.00 93.11  ?  4271 ALA   C HB1    1 
ATOM   4873 H  HB2    . ALA   B  2 19  ? 105.832 11.617  -18.851 1.00 93.11  ?  4271 ALA   C HB2    1 
ATOM   4874 H  HB3    . ALA   B  2 19  ? 106.138 10.061  -18.951 1.00 93.11  ?  4271 ALA   C HB3    1 
ATOM   4875 N  N      . PHE   B  2 20  ? 107.113 9.578   -15.788 1.00 86.00  ?  4272 PHE   C N      1 
ATOM   4876 C  CA     . PHE   B  2 20  ? 107.519 8.589   -14.793 1.00 80.74  ?  4272 PHE   C CA     1 
ATOM   4877 C  C      . PHE   B  2 20  ? 106.462 7.505   -14.663 1.00 82.95  ?  4272 PHE   C C      1 
ATOM   4878 O  O      . PHE   B  2 20  ? 105.331 7.772   -14.228 1.00 73.76  ?  4272 PHE   C O      1 
ATOM   4879 C  CB     . PHE   B  2 20  ? 107.776 9.244   -13.428 1.00 61.76  ?  4272 PHE   C CB     1 
ATOM   4880 C  CG     . PHE   B  2 20  ? 107.889 8.262   -12.276 1.00 50.69  ?  4272 PHE   C CG     1 
ATOM   4881 C  CD1    . PHE   B  2 20  ? 106.771 7.874   -11.558 1.00 51.89  ?  4272 PHE   C CD1    1 
ATOM   4882 C  CD2    . PHE   B  2 20  ? 109.117 7.742   -11.915 1.00 58.62  ?  4272 PHE   C CD2    1 
ATOM   4883 C  CE1    . PHE   B  2 20  ? 106.872 6.979   -10.515 1.00 47.79  ?  4272 PHE   C CE1    1 
ATOM   4884 C  CE2    . PHE   B  2 20  ? 109.226 6.845   -10.871 1.00 56.04  ?  4272 PHE   C CE2    1 
ATOM   4885 C  CZ     . PHE   B  2 20  ? 108.096 6.464   -10.167 1.00 46.42  ?  4272 PHE   C CZ     1 
ATOM   4886 H  H      . PHE   B  2 20  ? 106.372 9.973   -15.600 1.00 103.72 ?  4272 PHE   C H      1 
ATOM   4887 H  HA     . PHE   B  2 20  ? 108.337 8.170   -15.103 1.00 97.41  ?  4272 PHE   C HA     1 
ATOM   4888 H  HB2    . PHE   B  2 20  ? 108.608 9.740   -13.474 1.00 74.63  ?  4272 PHE   C HB2    1 
ATOM   4889 H  HB3    . PHE   B  2 20  ? 107.041 9.845   -13.230 1.00 74.63  ?  4272 PHE   C HB3    1 
ATOM   4890 H  HD1    . PHE   B  2 20  ? 105.939 8.222   -11.783 1.00 62.79  ?  4272 PHE   C HD1    1 
ATOM   4891 H  HD2    . PHE   B  2 20  ? 109.880 7.999   -12.380 1.00 70.87  ?  4272 PHE   C HD2    1 
ATOM   4892 H  HE1    . PHE   B  2 20  ? 106.111 6.724   -10.046 1.00 57.87  ?  4272 PHE   C HE1    1 
ATOM   4893 H  HE2    . PHE   B  2 20  ? 110.057 6.497   -10.640 1.00 67.77  ?  4272 PHE   C HE2    1 
ATOM   4894 H  HZ     . PHE   B  2 20  ? 108.166 5.862   -9.462  1.00 56.22  ?  4272 PHE   C HZ     1 
ATOM   4895 N  N      . ALA   B  2 21  ? 106.847 6.284   -15.023 1.00 77.56  ?  4273 ALA   C N      1 
ATOM   4896 C  CA     . ALA   B  2 21  ? 106.083 5.079   -14.742 1.00 64.20  ?  4273 ALA   C CA     1 
ATOM   4897 C  C      . ALA   B  2 21  ? 106.937 4.150   -13.893 1.00 64.07  ?  4273 ALA   C C      1 
ATOM   4898 O  O      . ALA   B  2 21  ? 108.109 3.921   -14.210 1.00 71.36  ?  4273 ALA   C O      1 
ATOM   4899 C  CB     . ALA   B  2 21  ? 105.678 4.370   -16.038 1.00 79.62  ?  4273 ALA   C CB     1 
ATOM   4900 H  H      . ALA   B  2 21  ? 107.577 6.125   -15.449 1.00 93.60  ?  4273 ALA   C H      1 
ATOM   4901 H  HA     . ALA   B  2 21  ? 105.277 5.306   -14.251 1.00 77.57  ?  4273 ALA   C HA     1 
ATOM   4902 H  HB1    . ALA   B  2 21  ? 105.163 3.578   -15.817 1.00 96.07  ?  4273 ALA   C HB1    1 
ATOM   4903 H  HB2    . ALA   B  2 21  ? 105.141 4.974   -16.574 1.00 96.07  ?  4273 ALA   C HB2    1 
ATOM   4904 H  HB3    . ALA   B  2 21  ? 106.479 4.119   -16.524 1.00 96.07  ?  4273 ALA   C HB3    1 
ATOM   4905 N  N      . VAL   B  2 22  ? 106.355 3.600   -12.827 1.00 60.78  ?  4274 VAL   C N      1 
ATOM   4906 C  CA     . VAL   B  2 22  ? 107.042 2.555   -12.074 1.00 64.34  ?  4274 VAL   C CA     1 
ATOM   4907 C  C      . VAL   B  2 22  ? 107.317 1.360   -12.975 1.00 69.00  ?  4274 VAL   C C      1 
ATOM   4908 O  O      . VAL   B  2 22  ? 106.489 1.003   -13.821 1.00 69.57  ?  4274 VAL   C O      1 
ATOM   4909 C  CB     . VAL   B  2 22  ? 106.194 2.153   -10.861 1.00 56.44  ?  4274 VAL   C CB     1 
ATOM   4910 C  CG1    . VAL   B  2 22  ? 104.957 1.412   -11.311 1.00 68.08  ?  4274 VAL   C CG1    1 
ATOM   4911 C  CG2    . VAL   B  2 22  ? 107.006 1.292   -9.923  1.00 65.52  ?  4274 VAL   C CG2    1 
ATOM   4912 H  H      . VAL   B  2 22  ? 105.577 3.810   -12.525 1.00 73.46  ?  4274 VAL   C H      1 
ATOM   4913 H  HA     . VAL   B  2 22  ? 107.895 2.894   -11.761 1.00 77.73  ?  4274 VAL   C HA     1 
ATOM   4914 H  HB     . VAL   B  2 22  ? 105.918 2.952   -10.386 1.00 68.25  ?  4274 VAL   C HB     1 
ATOM   4915 H  HG11   . VAL   B  2 22  ? 104.311 1.407   -10.587 1.00 82.22  ?  4274 VAL   C HG11   1 
ATOM   4916 H  HG12   . VAL   B  2 22  ? 104.583 1.863   -12.085 1.00 82.22  ?  4274 VAL   C HG12   1 
ATOM   4917 H  HG13   . VAL   B  2 22  ? 105.201 0.503   -11.544 1.00 82.22  ?  4274 VAL   C HG13   1 
ATOM   4918 H  HG21   . VAL   B  2 22  ? 106.485 1.116   -9.124  1.00 79.15  ?  4274 VAL   C HG21   1 
ATOM   4919 H  HG22   . VAL   B  2 22  ? 107.222 0.457   -10.367 1.00 79.15  ?  4274 VAL   C HG22   1 
ATOM   4920 H  HG23   . VAL   B  2 22  ? 107.822 1.762   -9.688  1.00 79.15  ?  4274 VAL   C HG23   1 
ATOM   4921 N  N      . ASP   B  2 23  ? 108.479 0.726   -12.799 1.00 64.03  ?  4275 ASP   C N      1 
ATOM   4922 C  CA     . ASP   B  2 23  ? 108.792 -0.532  -13.491 1.00 73.23  ?  4275 ASP   C CA     1 
ATOM   4923 C  C      . ASP   B  2 23  ? 108.699 -1.691  -12.517 1.00 72.54  ?  4275 ASP   C C      1 
ATOM   4924 O  O      . ASP   B  2 23  ? 109.644 -1.959  -11.769 1.00 63.26  ?  4275 ASP   C O      1 
ATOM   4925 C  CB     . ASP   B  2 23  ? 110.168 -0.535  -14.149 1.00 73.74  ?  4275 ASP   C CB     1 
ATOM   4926 C  CG     . ASP   B  2 23  ? 110.265 -1.566  -15.262 1.00 72.18  ?  4275 ASP   C CG     1 
ATOM   4927 O  OD1    . ASP   B  2 23  ? 109.228 -2.151  -15.621 1.00 69.03  ?  4275 ASP   C OD1    1 
ATOM   4928 O  OD2    . ASP   B  2 23  ? 111.384 -1.843  -15.733 1.00 85.03  ?  4275 ASP   C OD2    1 
ATOM   4929 H  H      . ASP   B  2 23  ? 109.106 1.006   -12.281 1.00 77.36  ?  4275 ASP   C H      1 
ATOM   4930 H  HA     . ASP   B  2 23  ? 108.115 -0.627  -14.179 1.00 88.40  ?  4275 ASP   C HA     1 
ATOM   4931 H  HB2    . ASP   B  2 23  ? 110.342 0.340   -14.531 1.00 89.01  ?  4275 ASP   C HB2    1 
ATOM   4932 H  HB3    . ASP   B  2 23  ? 110.841 -0.746  -13.482 1.00 89.01  ?  4275 ASP   C HB3    1 
ATOM   4933 N  N      . ALA   B  2 24  ? 107.570 -2.398  -12.548 1.00 72.45  ?  4276 ALA   C N      1 
ATOM   4934 C  CA     . ALA   B  2 24  ? 107.345 -3.517  -11.643 1.00 64.20  ?  4276 ALA   C CA     1 
ATOM   4935 C  C      . ALA   B  2 24  ? 108.023 -4.792  -12.133 1.00 52.70  ?  4276 ALA   C C      1 
ATOM   4936 O  O      . ALA   B  2 24  ? 108.598 -5.533  -11.328 1.00 50.93  ?  4276 ALA   C O      1 
ATOM   4937 C  CB     . ALA   B  2 24  ? 105.839 -3.748  -11.475 1.00 62.16  ?  4276 ALA   C CB     1 
ATOM   4938 H  H      . ALA   B  2 24  ? 106.918 -2.247  -13.088 1.00 87.46  ?  4276 ALA   C H      1 
ATOM   4939 H  HA     . ALA   B  2 24  ? 107.712 -3.305  -10.770 1.00 77.56  ?  4276 ALA   C HA     1 
ATOM   4940 H  HB1    . ALA   B  2 24  ? 105.699 -4.492  -10.868 1.00 75.11  ?  4276 ALA   C HB1    1 
ATOM   4941 H  HB2    . ALA   B  2 24  ? 105.435 -2.945  -11.112 1.00 75.11  ?  4276 ALA   C HB2    1 
ATOM   4942 H  HB3    . ALA   B  2 24  ? 105.452 -3.951  -12.341 1.00 75.11  ?  4276 ALA   C HB3    1 
ATOM   4943 N  N      . ALA   B  2 25  ? 107.937 -5.072  -13.438 1.00 56.86  ?  4277 ALA   C N      1 
ATOM   4944 C  CA     . ALA   B  2 25  ? 108.698 -6.172  -14.012 1.00 58.88  ?  4277 ALA   C CA     1 
ATOM   4945 C  C      . ALA   B  2 25  ? 110.138 -6.132  -13.517 1.00 61.20  ?  4277 ALA   C C      1 
ATOM   4946 O  O      . ALA   B  2 25  ? 110.625 -7.096  -12.913 1.00 55.32  ?  4277 ALA   C O      1 
ATOM   4947 C  CB     . ALA   B  2 25  ? 108.651 -6.118  -15.540 1.00 57.74  ?  4277 ALA   C CB     1 
ATOM   4948 H  H      . ALA   B  2 25  ? 107.449 -4.643  -14.001 1.00 68.76  ?  4277 ALA   C H      1 
ATOM   4949 H  HA     . ALA   B  2 25  ? 108.295 -7.012  -13.739 1.00 71.18  ?  4277 ALA   C HA     1 
ATOM   4950 H  HB1    . ALA   B  2 25  ? 109.164 -6.858  -15.898 1.00 69.81  ?  4277 ALA   C HB1    1 
ATOM   4951 H  HB2    . ALA   B  2 25  ? 107.727 -6.185  -15.830 1.00 69.81  ?  4277 ALA   C HB2    1 
ATOM   4952 H  HB3    . ALA   B  2 25  ? 109.031 -5.277  -15.838 1.00 69.81  ?  4277 ALA   C HB3    1 
ATOM   4953 N  N      . LYS   B  2 26  ? 110.823 -4.996  -13.715 1.00 62.69  ?  4278 LYS   C N      1 
ATOM   4954 C  CA     . LYS   B  2 26  ? 112.222 -4.910  -13.302 1.00 58.71  ?  4278 LYS   C CA     1 
ATOM   4955 C  C      . LYS   B  2 26  ? 112.361 -5.056  -11.787 1.00 54.64  ?  4278 LYS   C C      1 
ATOM   4956 O  O      . LYS   B  2 26  ? 113.302 -5.700  -11.298 1.00 57.66  ?  4278 LYS   C O      1 
ATOM   4957 C  CB     . LYS   B  2 26  ? 112.837 -3.583  -13.783 1.00 70.86  ?  4278 LYS   C CB     1 
ATOM   4958 C  CG     . LYS   B  2 26  ? 114.213 -3.287  -13.188 1.00 72.92  ?  4278 LYS   C CG     1 
ATOM   4959 C  CD     . LYS   B  2 26  ? 115.104 -2.448  -14.121 1.00 74.80  ?  4278 LYS   C CD     1 
ATOM   4960 C  CE     . LYS   B  2 26  ? 116.295 -1.821  -13.399 1.00 78.84  ?  4278 LYS   C CE     1 
ATOM   4961 N  NZ     . LYS   B  2 26  ? 115.946 -0.620  -12.595 1.00 91.12  ?  4278 LYS   C NZ     1 
ATOM   4962 H  H      . LYS   B  2 26  ? 110.506 -4.283  -14.077 1.00 75.76  ?  4278 LYS   C H      1 
ATOM   4963 H  HA     . LYS   B  2 26  ? 112.717 -5.633  -13.718 1.00 70.98  ?  4278 LYS   C HA     1 
ATOM   4964 H  HB2    . LYS   B  2 26  ? 112.933 -3.615  -14.748 1.00 85.56  ?  4278 LYS   C HB2    1 
ATOM   4965 H  HB3    . LYS   B  2 26  ? 112.245 -2.856  -13.533 1.00 85.56  ?  4278 LYS   C HB3    1 
ATOM   4966 H  HG2    . LYS   B  2 26  ? 114.100 -2.794  -12.360 1.00 88.03  ?  4278 LYS   C HG2    1 
ATOM   4967 H  HG3    . LYS   B  2 26  ? 114.669 -4.126  -13.015 1.00 88.03  ?  4278 LYS   C HG3    1 
ATOM   4968 H  HD2    . LYS   B  2 26  ? 115.448 -3.018  -14.826 1.00 90.29  ?  4278 LYS   C HD2    1 
ATOM   4969 H  HD3    . LYS   B  2 26  ? 114.574 -1.731  -14.503 1.00 90.29  ?  4278 LYS   C HD3    1 
ATOM   4970 H  HE2    . LYS   B  2 26  ? 116.676 -2.478  -12.796 1.00 95.13  ?  4278 LYS   C HE2    1 
ATOM   4971 H  HE3    . LYS   B  2 26  ? 116.954 -1.553  -14.058 1.00 95.13  ?  4278 LYS   C HE3    1 
ATOM   4972 H  HZ1    . LYS   B  2 26  ? 116.675 -0.294  -12.202 1.00 109.87 ?  4278 LYS   C HZ1    1 
ATOM   4973 H  HZ2    . LYS   B  2 26  ? 115.597 0.008   -13.121 1.00 109.87 ?  4278 LYS   C HZ2    1 
ATOM   4974 H  HZ3    . LYS   B  2 26  ? 115.351 -0.835  -11.969 1.00 109.87 ?  4278 LYS   C HZ3    1 
ATOM   4975 N  N      . ALA   B  2 27  ? 111.430 -4.472  -11.026 1.00 55.67  ?  4279 ALA   C N      1 
ATOM   4976 C  CA     . ALA   B  2 27  ? 111.508 -4.564  -9.572  1.00 55.79  ?  4279 ALA   C CA     1 
ATOM   4977 C  C      . ALA   B  2 27  ? 111.459 -6.012  -9.106  1.00 58.36  ?  4279 ALA   C C      1 
ATOM   4978 O  O      . ALA   B  2 27  ? 112.225 -6.406  -8.215  1.00 54.13  ?  4279 ALA   C O      1 
ATOM   4979 C  CB     . ALA   B  2 27  ? 110.382 -3.767  -8.916  1.00 58.81  ?  4279 ALA   C CB     1 
ATOM   4980 H  H      . ALA   B  2 27  ? 110.756 -4.028  -11.324 1.00 67.32  ?  4279 ALA   C H      1 
ATOM   4981 H  HA     . ALA   B  2 27  ? 112.351 -4.175  -9.292  1.00 67.48  ?  4279 ALA   C HA     1 
ATOM   4982 H  HB1    . ALA   B  2 27  ? 110.453 -3.856  -7.952  1.00 71.10  ?  4279 ALA   C HB1    1 
ATOM   4983 H  HB2    . ALA   B  2 27  ? 110.466 -2.834  -9.169  1.00 71.10  ?  4279 ALA   C HB2    1 
ATOM   4984 H  HB3    . ALA   B  2 27  ? 109.530 -4.116  -9.219  1.00 71.10  ?  4279 ALA   C HB3    1 
ATOM   4985 N  N      . TYR   B  2 28  ? 110.569 -6.823  -9.693  1.00 53.29  ?  4280 TYR   C N      1 
ATOM   4986 C  CA     . TYR   B  2 28  ? 110.484 -8.220  -9.285  1.00 57.69  ?  4280 TYR   C CA     1 
ATOM   4987 C  C      . TYR   B  2 28  ? 111.725 -8.990  -9.732  1.00 55.11  ?  4280 TYR   C C      1 
ATOM   4988 O  O      . TYR   B  2 28  ? 112.273 -9.794  -8.969  1.00 50.23  ?  4280 TYR   C O      1 
ATOM   4989 C  CB     . TYR   B  2 28  ? 109.207 -8.846  -9.856  1.00 55.88  ?  4280 TYR   C CB     1 
ATOM   4990 C  CG     . TYR   B  2 28  ? 108.909 -10.217 -9.298  1.00 49.23  ?  4280 TYR   C CG     1 
ATOM   4991 C  CD1    . TYR   B  2 28  ? 108.899 -10.439 -7.920  1.00 46.44  ?  4280 TYR   C CD1    1 
ATOM   4992 C  CD2    . TYR   B  2 28  ? 108.631 -11.282 -10.137 1.00 51.68  ?  4280 TYR   C CD2    1 
ATOM   4993 C  CE1    . TYR   B  2 28  ? 108.629 -11.690 -7.389  1.00 52.63  ?  4280 TYR   C CE1    1 
ATOM   4994 C  CE2    . TYR   B  2 28  ? 108.361 -12.547 -9.611  1.00 50.19  ?  4280 TYR   C CE2    1 
ATOM   4995 C  CZ     . TYR   B  2 28  ? 108.367 -12.736 -8.239  1.00 52.10  ?  4280 TYR   C CZ     1 
ATOM   4996 O  OH     . TYR   B  2 28  ? 108.111 -13.978 -7.717  1.00 48.07  ?  4280 TYR   C OH     1 
ATOM   4997 H  H      . TYR   B  2 28  ? 110.020 -6.591  -10.312 1.00 64.47  ?  4280 TYR   C H      1 
ATOM   4998 H  HA     . TYR   B  2 28  ? 110.433 -8.276  -8.318  1.00 69.75  ?  4280 TYR   C HA     1 
ATOM   4999 H  HB2    . TYR   B  2 28  ? 108.455 -8.270  -9.647  1.00 67.58  ?  4280 TYR   C HB2    1 
ATOM   5000 H  HB3    . TYR   B  2 28  ? 109.302 -8.931  -10.818 1.00 67.58  ?  4280 TYR   C HB3    1 
ATOM   5001 H  HD1    . TYR   B  2 28  ? 109.077 -9.730  -7.344  1.00 56.24  ?  4280 TYR   C HD1    1 
ATOM   5002 H  HD2    . TYR   B  2 28  ? 108.624 -11.155 -11.058 1.00 62.54  ?  4280 TYR   C HD2    1 
ATOM   5003 H  HE1    . TYR   B  2 28  ? 108.624 -11.820 -6.468  1.00 63.68  ?  4280 TYR   C HE1    1 
ATOM   5004 H  HE2    . TYR   B  2 28  ? 108.178 -13.259 -10.179 1.00 60.75  ?  4280 TYR   C HE2    1 
ATOM   5005 H  HH     . TYR   B  2 28  ? 108.004 -14.534 -8.337  1.00 58.20  ?  4280 TYR   C HH     1 
ATOM   5006 N  N      . LYS   B  2 29  ? 112.219 -8.714  -10.947 1.00 59.36  ?  4281 LYS   C N      1 
ATOM   5007 C  CA     . LYS   B  2 29  ? 113.418 -9.400  -11.428 1.00 52.53  ?  4281 LYS   C CA     1 
ATOM   5008 C  C      . LYS   B  2 29  ? 114.614 -9.115  -10.523 1.00 55.58  ?  4281 LYS   C C      1 
ATOM   5009 O  O      . LYS   B  2 29  ? 115.353 -10.032 -10.142 1.00 59.73  ?  4281 LYS   C O      1 
ATOM   5010 C  CB     . LYS   B  2 29  ? 113.714 -8.996  -12.870 1.00 51.07  ?  4281 LYS   C CB     1 
ATOM   5011 C  CG     . LYS   B  2 29  ? 112.770 -9.623  -13.908 1.00 59.65  ?  4281 LYS   C CG     1 
ATOM   5012 C  CD     . LYS   B  2 29  ? 112.941 -9.043  -15.300 1.00 70.75  ?  4281 LYS   C CD     1 
ATOM   5013 C  CE     . LYS   B  2 29  ? 111.726 -9.357  -16.180 1.00 67.81  ?  4281 LYS   C CE     1 
ATOM   5014 N  NZ     . LYS   B  2 29  ? 111.888 -8.912  -17.600 1.00 70.75  ?  4281 LYS   C NZ     1 
ATOM   5015 H  H      . LYS   B  2 29  ? 111.883 -8.147  -11.499 1.00 71.76  ?  4281 LYS   C H      1 
ATOM   5016 H  HA     . LYS   B  2 29  ? 113.257 -10.356 -11.416 1.00 63.56  ?  4281 LYS   C HA     1 
ATOM   5017 H  HB2    . LYS   B  2 29  ? 113.634 -8.032  -12.944 1.00 61.81  ?  4281 LYS   C HB2    1 
ATOM   5018 H  HB3    . LYS   B  2 29  ? 114.617 -9.272  -13.090 1.00 61.81  ?  4281 LYS   C HB3    1 
ATOM   5019 H  HG2    . LYS   B  2 29  ? 112.946 -10.576 -13.959 1.00 72.10  ?  4281 LYS   C HG2    1 
ATOM   5020 H  HG3    . LYS   B  2 29  ? 111.852 -9.470  -13.633 1.00 72.10  ?  4281 LYS   C HG3    1 
ATOM   5021 H  HD2    . LYS   B  2 29  ? 113.035 -8.079  -15.239 1.00 85.42  ?  4281 LYS   C HD2    1 
ATOM   5022 H  HD3    . LYS   B  2 29  ? 113.729 -9.427  -15.715 1.00 85.42  ?  4281 LYS   C HD3    1 
ATOM   5023 H  HE2    . LYS   B  2 29  ? 111.582 -10.316 -16.184 1.00 81.90  ?  4281 LYS   C HE2    1 
ATOM   5024 H  HE3    . LYS   B  2 29  ? 110.949 -8.906  -15.814 1.00 81.90  ?  4281 LYS   C HE3    1 
ATOM   5025 H  HZ1    . LYS   B  2 29  ? 111.158 -9.114  -18.067 1.00 85.42  ?  4281 LYS   C HZ1    1 
ATOM   5026 H  HZ2    . LYS   B  2 29  ? 112.016 -8.032  -17.631 1.00 85.42  ?  4281 LYS   C HZ2    1 
ATOM   5027 H  HZ3    . LYS   B  2 29  ? 112.589 -9.319  -17.969 1.00 85.42  ?  4281 LYS   C HZ3    1 
ATOM   5028 N  N      . ASP   B  2 30  ? 114.838 -7.844  -10.184 1.00 64.54  ?  4282 ASP   C N      1 
ATOM   5029 C  CA     . ASP   B  2 30  ? 115.939 -7.527  -9.275  1.00 56.42  ?  4282 ASP   C CA     1 
ATOM   5030 C  C      . ASP   B  2 30  ? 115.688 -8.117  -7.881  1.00 55.56  ?  4282 ASP   C C      1 
ATOM   5031 O  O      . ASP   B  2 30  ? 116.619 -8.630  -7.245  1.00 64.70  ?  4282 ASP   C O      1 
ATOM   5032 C  CB     . ASP   B  2 30  ? 116.151 -6.008  -9.195  1.00 58.19  ?  4282 ASP   C CB     1 
ATOM   5033 C  CG     . ASP   B  2 30  ? 116.516 -5.378  -10.533 1.00 67.53  ?  4282 ASP   C CG     1 
ATOM   5034 O  OD1    . ASP   B  2 30  ? 116.951 -6.092  -11.452 1.00 65.42  ?  4282 ASP   C OD1    1 
ATOM   5035 O  OD2    . ASP   B  2 30  ? 116.413 -4.142  -10.651 1.00 68.04  ?  4282 ASP   C OD2    1 
ATOM   5036 H  H      . ASP   B  2 30  ? 114.383 -7.168  -10.457 1.00 77.97  ?  4282 ASP   C H      1 
ATOM   5037 H  HA     . ASP   B  2 30  ? 116.755 -7.917  -9.626  1.00 68.23  ?  4282 ASP   C HA     1 
ATOM   5038 H  HB2    . ASP   B  2 30  ? 115.332 -5.592  -8.885  1.00 70.35  ?  4282 ASP   C HB2    1 
ATOM   5039 H  HB3    . ASP   B  2 30  ? 116.873 -5.824  -8.573  1.00 70.35  ?  4282 ASP   C HB3    1 
ATOM   5040 N  N      . TYR   B  2 31  ? 114.442 -8.059  -7.394  1.00 63.29  ?  4283 TYR   C N      1 
ATOM   5041 C  CA     . TYR   B  2 31  ? 114.091 -8.703  -6.125  1.00 67.47  ?  4283 TYR   C CA     1 
ATOM   5042 C  C      . TYR   B  2 31  ? 114.441 -10.181 -6.143  1.00 65.43  ?  4283 TYR   C C      1 
ATOM   5043 O  O      . TYR   B  2 31  ? 114.991 -10.705 -5.168  1.00 61.75  ?  4283 TYR   C O      1 
ATOM   5044 C  CB     . TYR   B  2 31  ? 112.591 -8.509  -5.844  1.00 60.32  ?  4283 TYR   C CB     1 
ATOM   5045 C  CG     . TYR   B  2 31  ? 111.991 -9.352  -4.728  1.00 58.72  ?  4283 TYR   C CG     1 
ATOM   5046 C  CD1    . TYR   B  2 31  ? 111.926 -8.882  -3.411  1.00 58.34  ?  4283 TYR   C CD1    1 
ATOM   5047 C  CD2    . TYR   B  2 31  ? 111.437 -10.596 -5.004  1.00 63.89  ?  4283 TYR   C CD2    1 
ATOM   5048 C  CE1    . TYR   B  2 31  ? 111.361 -9.646  -2.395  1.00 69.33  ?  4283 TYR   C CE1    1 
ATOM   5049 C  CE2    . TYR   B  2 31  ? 110.878 -11.362 -4.000  1.00 61.78  ?  4283 TYR   C CE2    1 
ATOM   5050 C  CZ     . TYR   B  2 31  ? 110.841 -10.882 -2.704  1.00 70.21  ?  4283 TYR   C CZ     1 
ATOM   5051 O  OH     . TYR   B  2 31  ? 110.278 -11.658 -1.719  1.00 73.98  ?  4283 TYR   C OH     1 
ATOM   5052 H  H      . TYR   B  2 31  ? 113.786 -7.656  -7.777  1.00 76.46  ?  4283 TYR   C H      1 
ATOM   5053 H  HA     . TYR   B  2 31  ? 114.595 -8.285  -5.409  1.00 81.49  ?  4283 TYR   C HA     1 
ATOM   5054 H  HB2    . TYR   B  2 31  ? 112.448 -7.579  -5.606  1.00 72.90  ?  4283 TYR   C HB2    1 
ATOM   5055 H  HB3    . TYR   B  2 31  ? 112.103 -8.722  -6.655  1.00 72.90  ?  4283 TYR   C HB3    1 
ATOM   5056 H  HD1    . TYR   B  2 31  ? 112.269 -8.041  -3.212  1.00 70.53  ?  4283 TYR   C HD1    1 
ATOM   5057 H  HD2    . TYR   B  2 31  ? 111.443 -10.917 -5.876  1.00 77.19  ?  4283 TYR   C HD2    1 
ATOM   5058 H  HE1    . TYR   B  2 31  ? 111.336 -9.327  -1.522  1.00 83.72  ?  4283 TYR   C HE1    1 
ATOM   5059 H  HE2    . TYR   B  2 31  ? 110.526 -12.200 -4.195  1.00 74.66  ?  4283 TYR   C HE2    1 
ATOM   5060 H  HH     . TYR   B  2 31  ? 109.992 -12.376 -2.047  1.00 89.30  ?  4283 TYR   C HH     1 
ATOM   5061 N  N      . LEU   B  2 32  ? 114.145 -10.869 -7.245  1.00 55.87  ?  4284 LEU   C N      1 
ATOM   5062 C  CA     . LEU   B  2 32  ? 114.483 -12.283 -7.333  1.00 63.83  ?  4284 LEU   C CA     1 
ATOM   5063 C  C      . LEU   B  2 32  ? 115.994 -12.493 -7.343  1.00 62.36  ?  4284 LEU   C C      1 
ATOM   5064 O  O      . LEU   B  2 32  ? 116.525 -13.295 -6.563  1.00 59.60  ?  4284 LEU   C O      1 
ATOM   5065 C  CB     . LEU   B  2 32  ? 113.858 -12.881 -8.593  1.00 65.92  ?  4284 LEU   C CB     1 
ATOM   5066 C  CG     . LEU   B  2 32  ? 112.347 -13.076 -8.549  1.00 52.92  ?  4284 LEU   C CG     1 
ATOM   5067 C  CD1    . LEU   B  2 32  ? 111.834 -13.621 -9.878  1.00 52.91  ?  4284 LEU   C CD1    1 
ATOM   5068 C  CD2    . LEU   B  2 32  ? 111.956 -13.977 -7.415  1.00 52.78  ?  4284 LEU   C CD2    1 
ATOM   5069 H  H      . LEU   B  2 32  ? 113.756 -10.545 -7.941  1.00 67.56  ?  4284 LEU   C H      1 
ATOM   5070 H  HA     . LEU   B  2 32  ? 114.122 -12.740 -6.557  1.00 77.11  ?  4284 LEU   C HA     1 
ATOM   5071 H  HB2    . LEU   B  2 32  ? 114.052 -12.290 -9.338  1.00 79.63  ?  4284 LEU   C HB2    1 
ATOM   5072 H  HB3    . LEU   B  2 32  ? 114.258 -13.751 -8.747  1.00 79.63  ?  4284 LEU   C HB3    1 
ATOM   5073 H  HG     . LEU   B  2 32  ? 111.927 -12.214 -8.399  1.00 64.03  ?  4284 LEU   C HG     1 
ATOM   5074 H  HD11   . LEU   B  2 32  ? 110.883 -13.796 -9.801  1.00 64.02  ?  4284 LEU   C HD11   1 
ATOM   5075 H  HD12   . LEU   B  2 32  ? 111.994 -12.963 -10.573 1.00 64.02  ?  4284 LEU   C HD12   1 
ATOM   5076 H  HD13   . LEU   B  2 32  ? 112.306 -14.443 -10.086 1.00 64.02  ?  4284 LEU   C HD13   1 
ATOM   5077 H  HD21   . LEU   B  2 32  ? 111.060 -14.313 -7.574  1.00 63.85  ?  4284 LEU   C HD21   1 
ATOM   5078 H  HD22   . LEU   B  2 32  ? 112.583 -14.716 -7.368  1.00 63.85  ?  4284 LEU   C HD22   1 
ATOM   5079 H  HD23   . LEU   B  2 32  ? 111.978 -13.472 -6.588  1.00 63.85  ?  4284 LEU   C HD23   1 
ATOM   5080 N  N      . ALA   B  2 33  ? 116.702 -11.763 -8.216  1.00 62.19  ?  4285 ALA   C N      1 
ATOM   5081 C  CA     . ALA   B  2 33  ? 118.156 -11.872 -8.290  1.00 58.70  ?  4285 ALA   C CA     1 
ATOM   5082 C  C      . ALA   B  2 33  ? 118.797 -11.643 -6.926  1.00 61.17  ?  4285 ALA   C C      1 
ATOM   5083 O  O      . ALA   B  2 33  ? 119.707 -12.376 -6.527  1.00 62.34  ?  4285 ALA   C O      1 
ATOM   5084 C  CB     . ALA   B  2 33  ? 118.705 -10.884 -9.315  1.00 57.14  ?  4285 ALA   C CB     1 
ATOM   5085 H  H      . ALA   B  2 33  ? 116.362 -11.202 -8.772  1.00 75.15  ?  4285 ALA   C H      1 
ATOM   5086 H  HA     . ALA   B  2 33  ? 118.389 -12.766 -8.584  1.00 70.96  ?  4285 ALA   C HA     1 
ATOM   5087 H  HB1    . ALA   B  2 33  ? 119.672 -10.963 -9.344  1.00 69.09  ?  4285 ALA   C HB1    1 
ATOM   5088 H  HB2    . ALA   B  2 33  ? 118.331 -11.092 -10.186 1.00 69.09  ?  4285 ALA   C HB2    1 
ATOM   5089 H  HB3    . ALA   B  2 33  ? 118.454 -9.985  -9.053  1.00 69.09  ?  4285 ALA   C HB3    1 
ATOM   5090 N  N      . SER   B  2 34  ? 118.333 -10.630 -6.195  1.00 63.26  ?  4286 SER   C N      1 
ATOM   5091 C  CA     . SER   B  2 34  ? 118.825 -10.363 -4.852  1.00 61.85  ?  4286 SER   C CA     1 
ATOM   5092 C  C      . SER   B  2 34  ? 118.462 -11.441 -3.851  1.00 58.46  ?  4286 SER   C C      1 
ATOM   5093 O  O      . SER   B  2 34  ? 118.856 -11.316 -2.690  1.00 63.77  ?  4286 SER   C O      1 
ATOM   5094 C  CB     . SER   B  2 34  ? 118.288 -9.021  -4.364  1.00 64.64  ?  4286 SER   C CB     1 
ATOM   5095 O  OG     . SER   B  2 34  ? 117.114 -9.208  -3.597  1.00 84.16  ?  4286 SER   C OG     1 
ATOM   5096 H  H      . SER   B  2 34  ? 117.727 -10.081 -6.460  1.00 76.44  ?  4286 SER   C H      1 
ATOM   5097 H  HA     . SER   B  2 34  ? 119.793 -10.313 -4.890  1.00 74.74  ?  4286 SER   C HA     1 
ATOM   5098 H  HB2    . SER   B  2 34  ? 118.961 -8.590  -3.815  1.00 78.08  ?  4286 SER   C HB2    1 
ATOM   5099 H  HB3    . SER   B  2 34  ? 118.080 -8.464  -5.131  1.00 78.08  ?  4286 SER   C HB3    1 
ATOM   5100 H  HG     . SER   B  2 34  ? 116.522 -9.581  -4.062  1.00 101.51 ?  4286 SER   C HG     1 
ATOM   5101 N  N      . GLY   B  2 35  ? 117.723 -12.471 -4.255  1.00 69.53  ?  4287 GLY   C N      1 
ATOM   5102 C  CA     . GLY   B  2 35  ? 117.434 -13.578 -3.368  1.00 69.34  ?  4287 GLY   C CA     1 
ATOM   5103 C  C      . GLY   B  2 35  ? 116.112 -13.515 -2.652  1.00 64.00  ?  4287 GLY   C C      1 
ATOM   5104 O  O      . GLY   B  2 35  ? 115.936 -14.235 -1.666  1.00 60.71  ?  4287 GLY   C O      1 
ATOM   5105 H  H      . GLY   B  2 35  ? 117.380 -12.547 -5.040  1.00 83.96  ?  4287 GLY   C H      1 
ATOM   5106 H  HA2    . GLY   B  2 35  ? 117.447 -14.398 -3.886  1.00 83.73  ?  4287 GLY   C HA2    1 
ATOM   5107 H  HA3    . GLY   B  2 35  ? 118.130 -13.619 -2.693  1.00 83.73  ?  4287 GLY   C HA3    1 
ATOM   5108 N  N      . GLY   B  2 36  ? 115.169 -12.695 -3.105  1.00 65.50  ?  4288 GLY   C N      1 
ATOM   5109 C  CA     . GLY   B  2 36  ? 113.889 -12.627 -2.424  1.00 68.27  ?  4288 GLY   C CA     1 
ATOM   5110 C  C      . GLY   B  2 36  ? 112.997 -13.805 -2.770  1.00 63.17  ?  4288 GLY   C C      1 
ATOM   5111 O  O      . GLY   B  2 36  ? 113.098 -14.400 -3.847  1.00 62.05  ?  4288 GLY   C O      1 
ATOM   5112 H  H      . GLY   B  2 36  ? 115.245 -12.181 -3.790  1.00 79.12  ?  4288 GLY   C H      1 
ATOM   5113 H  HA2    . GLY   B  2 36  ? 114.035 -12.623 -1.464  1.00 82.44  ?  4288 GLY   C HA2    1 
ATOM   5114 H  HA3    . GLY   B  2 36  ? 113.432 -11.810 -2.677  1.00 82.44  ?  4288 GLY   C HA3    1 
ATOM   5115 N  N      . GLN   B  2 37  ? 112.107 -14.155 -1.829  1.00 65.29  ?  4289 GLN   C N      1 
ATOM   5116 C  CA     . GLN   B  2 37  ? 111.280 -15.336 -2.058  1.00 67.99  ?  4289 GLN   C CA     1 
ATOM   5117 C  C      . GLN   B  2 37  ? 110.166 -15.020 -3.061  1.00 57.71  ?  4289 GLN   C C      1 
ATOM   5118 O  O      . GLN   B  2 37  ? 109.539 -13.954 -2.986  1.00 60.65  ?  4289 GLN   C O      1 
ATOM   5119 C  CB     . GLN   B  2 37  ? 110.698 -15.848 -0.742  1.00 71.08  ?  4289 GLN   C CB     1 
ATOM   5120 C  CG     . GLN   B  2 37  ? 111.678 -16.599 0.172   1.00 89.70  ?  4289 GLN   C CG     1 
ATOM   5121 C  CD     . GLN   B  2 37  ? 112.493 -17.666 -0.528  1.00 102.42 ?  4289 GLN   C CD     1 
ATOM   5122 O  OE1    . GLN   B  2 37  ? 113.543 -17.388 -1.085  1.00 77.99  ?  4289 GLN   C OE1    1 
ATOM   5123 N  NE2    . GLN   B  2 37  ? 112.028 -18.901 -0.468  1.00 107.38 ?  4289 GLN   C NE2    1 
ATOM   5124 H  H      . GLN   B  2 37  ? 111.972 -13.742 -1.087  1.00 78.87  ?  4289 GLN   C H      1 
ATOM   5125 H  HA     . GLN   B  2 37  ? 111.820 -16.048 -2.435  1.00 82.11  ?  4289 GLN   C HA     1 
ATOM   5126 H  HB2    . GLN   B  2 37  ? 110.363 -15.087 -0.241  1.00 85.82  ?  4289 GLN   C HB2    1 
ATOM   5127 H  HB3    . GLN   B  2 37  ? 109.971 -16.456 -0.946  1.00 85.82  ?  4289 GLN   C HB3    1 
ATOM   5128 H  HG2    . GLN   B  2 37  ? 112.299 -15.959 0.554   1.00 108.16 ?  4289 GLN   C HG2    1 
ATOM   5129 H  HG3    . GLN   B  2 37  ? 111.173 -17.032 0.878   1.00 108.16 ?  4289 GLN   C HG3    1 
ATOM   5130 H  HE21   . GLN   B  2 37  ? 111.297 -19.065 -0.045  1.00 129.37 ?  4289 GLN   C HE21   1 
ATOM   5131 H  HE22   . GLN   B  2 37  ? 112.456 -19.541 -0.851  1.00 129.37 ?  4289 GLN   C HE22   1 
ATOM   5132 N  N      . PRO   B  2 38  ? 109.920 -15.912 -4.024  1.00 55.97  ?  4290 PRO   C N      1 
ATOM   5133 C  CA     . PRO   B  2 38  ? 108.954 -15.598 -5.082  1.00 54.41  ?  4290 PRO   C CA     1 
ATOM   5134 C  C      . PRO   B  2 38  ? 107.556 -15.404 -4.522  1.00 51.43  ?  4290 PRO   C C      1 
ATOM   5135 O  O      . PRO   B  2 38  ? 107.217 -15.882 -3.437  1.00 55.41  ?  4290 PRO   C O      1 
ATOM   5136 C  CB     . PRO   B  2 38  ? 109.011 -16.826 -6.006  1.00 59.26  ?  4290 PRO   C CB     1 
ATOM   5137 C  CG     . PRO   B  2 38  ? 110.308 -17.497 -5.678  1.00 55.87  ?  4290 PRO   C CG     1 
ATOM   5138 C  CD     . PRO   B  2 38  ? 110.568 -17.221 -4.235  1.00 51.10  ?  4290 PRO   C CD     1 
ATOM   5139 H  HA     . PRO   B  2 38  ? 109.228 -14.805 -5.568  1.00 65.81  ?  4290 PRO   C HA     1 
ATOM   5140 H  HB2    . PRO   B  2 38  ? 108.261 -17.413 -5.823  1.00 71.64  ?  4290 PRO   C HB2    1 
ATOM   5141 H  HB3    . PRO   B  2 38  ? 108.992 -16.542 -6.933  1.00 71.64  ?  4290 PRO   C HB3    1 
ATOM   5142 H  HG2    . PRO   B  2 38  ? 110.230 -18.451 -5.836  1.00 67.57  ?  4290 PRO   C HG2    1 
ATOM   5143 H  HG3    . PRO   B  2 38  ? 111.015 -17.126 -6.229  1.00 67.57  ?  4290 PRO   C HG3    1 
ATOM   5144 H  HD2    . PRO   B  2 38  ? 110.163 -17.902 -3.674  1.00 61.85  ?  4290 PRO   C HD2    1 
ATOM   5145 H  HD3    . PRO   B  2 38  ? 111.520 -17.169 -4.058  1.00 61.85  ?  4290 PRO   C HD3    1 
ATOM   5146 N  N      . ILE   B  2 39  ? 106.742 -14.680 -5.294  1.00 50.30  ?  4291 ILE   C N      1 
ATOM   5147 C  CA     . ILE   B  2 39  ? 105.339 -14.511 -4.956  1.00 50.63  ?  4291 ILE   C CA     1 
ATOM   5148 C  C      . ILE   B  2 39  ? 104.692 -15.873 -4.806  1.00 49.16  ?  4291 ILE   C C      1 
ATOM   5149 O  O      . ILE   B  2 39  ? 104.927 -16.789 -5.607  1.00 50.21  ?  4291 ILE   C O      1 
ATOM   5150 C  CB     . ILE   B  2 39  ? 104.634 -13.676 -6.037  1.00 56.34  ?  4291 ILE   C CB     1 
ATOM   5151 C  CG1    . ILE   B  2 39  ? 105.311 -12.315 -6.106  1.00 44.48  ?  4291 ILE   C CG1    1 
ATOM   5152 C  CG2    . ILE   B  2 39  ? 103.172 -13.541 -5.722  1.00 52.90  ?  4291 ILE   C CG2    1 
ATOM   5153 C  CD1    . ILE   B  2 39  ? 104.849 -11.470 -7.239  1.00 43.47  ?  4291 ILE   C CD1    1 
ATOM   5154 H  H      . ILE   B  2 39  ? 106.982 -14.279 -6.016  1.00 60.88  ?  4291 ILE   C H      1 
ATOM   5155 H  HA     . ILE   B  2 39  ? 105.265 -14.040 -4.112  1.00 61.27  ?  4291 ILE   C HA     1 
ATOM   5156 H  HB     . ILE   B  2 39  ? 104.706 -14.116 -6.898  1.00 68.13  ?  4291 ILE   C HB     1 
ATOM   5157 H  HG12   . ILE   B  2 39  ? 105.127 -11.833 -5.284  1.00 53.90  ?  4291 ILE   C HG12   1 
ATOM   5158 H  HG13   . ILE   B  2 39  ? 106.266 -12.447 -6.206  1.00 53.90  ?  4291 ILE   C HG13   1 
ATOM   5159 H  HG21   . ILE   B  2 39  ? 102.755 -12.979 -6.394  1.00 64.01  ?  4291 ILE   C HG21   1 
ATOM   5160 H  HG22   . ILE   B  2 39  ? 102.765 -14.421 -5.728  1.00 64.01  ?  4291 ILE   C HG22   1 
ATOM   5161 H  HG23   . ILE   B  2 39  ? 103.074 -13.137 -4.846  1.00 64.01  ?  4291 ILE   C HG23   1 
ATOM   5162 H  HD11   . ILE   B  2 39  ? 105.486 -10.752 -7.378  1.00 52.69  ?  4291 ILE   C HD11   1 
ATOM   5163 H  HD12   . ILE   B  2 39  ? 104.788 -12.018 -8.038  1.00 52.69  ?  4291 ILE   C HD12   1 
ATOM   5164 H  HD13   . ILE   B  2 39  ? 103.977 -11.102 -7.024  1.00 52.69  ?  4291 ILE   C HD13   1 
ATOM   5165 N  N      . THR   B  2 40  ? 103.847 -15.997 -3.798  1.00 50.87  ?  4292 THR   C N      1 
ATOM   5166 C  CA     . THR   B  2 40  ? 103.235 -17.246 -3.392  1.00 50.24  ?  4292 THR   C CA     1 
ATOM   5167 C  C      . THR   B  2 40  ? 101.731 -17.143 -3.582  1.00 47.54  ?  4292 THR   C C      1 
ATOM   5168 O  O      . THR   B  2 40  ? 101.201 -16.096 -3.981  1.00 47.19  ?  4292 THR   C O      1 
ATOM   5169 C  CB     . THR   B  2 40  ? 103.589 -17.553 -1.939  1.00 50.16  ?  4292 THR   C CB     1 
ATOM   5170 O  OG1    . THR   B  2 40  ? 102.983 -16.577 -1.084  1.00 50.89  ?  4292 THR   C OG1    1 
ATOM   5171 C  CG2    . THR   B  2 40  ? 105.096 -17.509 -1.742  1.00 63.38  ?  4292 THR   C CG2    1 
ATOM   5172 H  H      . THR   B  2 40  ? 103.601 -15.335 -3.308  1.00 61.57  ?  4292 THR   C H      1 
ATOM   5173 H  HA     . THR   B  2 40  ? 103.568 -17.970 -3.945  1.00 60.81  ?  4292 THR   C HA     1 
ATOM   5174 H  HB     . THR   B  2 40  ? 103.268 -18.438 -1.708  1.00 60.72  ?  4292 THR   C HB     1 
ATOM   5175 H  HG1    . THR   B  2 40  ? 103.188 -16.729 -0.284  1.00 61.59  ?  4292 THR   C HG1    1 
ATOM   5176 H  HG21   . THR   B  2 40  ? 105.316 -17.710 -0.819  1.00 76.58  ?  4292 THR   C HG21   1 
ATOM   5177 H  HG22   . THR   B  2 40  ? 105.525 -18.161 -2.318  1.00 76.58  ?  4292 THR   C HG22   1 
ATOM   5178 H  HG23   . THR   B  2 40  ? 105.433 -16.626 -1.961  1.00 76.58  ?  4292 THR   C HG23   1 
ATOM   5179 N  N      . ASN   B  2 41  ? 101.056 -18.253 -3.288  1.00 46.53  ?  4293 ASN   C N      1 
ATOM   5180 C  CA     . ASN   B  2 41  ? 99.610  -18.355 -3.340  1.00 44.79  ?  4293 ASN   C CA     1 
ATOM   5181 C  C      . ASN   B  2 41  ? 99.068  -18.216 -4.748  1.00 42.63  ?  4293 ASN   C C      1 
ATOM   5182 O  O      . ASN   B  2 41  ? 97.873  -17.950 -4.924  1.00 44.41  ?  4293 ASN   C O      1 
ATOM   5183 C  CB     . ASN   B  2 41  ? 98.973  -17.340 -2.396  1.00 44.40  ?  4293 ASN   C CB     1 
ATOM   5184 C  CG     . ASN   B  2 41  ? 99.245  -17.655 -0.950  1.00 46.68  ?  4293 ASN   C CG     1 
ATOM   5185 O  OD1    . ASN   B  2 41  ? 98.954  -18.751 -0.486  1.00 53.03  ?  4293 ASN   C OD1    1 
ATOM   5186 N  ND2    . ASN   B  2 41  ? 99.867  -16.727 -0.250  1.00 53.10  ?  4293 ASN   C ND2    1 
ATOM   5187 H  H      . ASN   B  2 41  ? 101.435 -18.986 -3.047  1.00 56.35  ?  4293 ASN   C H      1 
ATOM   5188 H  HA     . ASN   B  2 41  ? 99.343  -19.239 -3.041  1.00 54.27  ?  4293 ASN   C HA     1 
ATOM   5189 H  HB2    . ASN   B  2 41  ? 99.332  -16.460 -2.587  1.00 53.80  ?  4293 ASN   C HB2    1 
ATOM   5190 H  HB3    . ASN   B  2 41  ? 98.012  -17.342 -2.530  1.00 53.80  ?  4293 ASN   C HB3    1 
ATOM   5191 H  HD21   . ASN   B  2 41  ? 100.044 -16.861 0.580   1.00 64.25  ?  4293 ASN   C HD21   1 
ATOM   5192 H  HD22   . ASN   B  2 41  ? 100.095 -15.987 -0.625  1.00 64.25  ?  4293 ASN   C HD22   1 
ATOM   5193 N  N      . CYS   B  2 42  ? 99.913  -18.386 -5.761  1.00 41.52  ?  4294 CYS   C N      1 
ATOM   5194 C  CA     . CYS   B  2 42  ? 99.379  -18.740 -7.066  1.00 45.79  ?  4294 CYS   C CA     1 
ATOM   5195 C  C      . CYS   B  2 42  ? 98.556  -20.015 -6.985  1.00 41.24  ?  4294 CYS   C C      1 
ATOM   5196 O  O      . CYS   B  2 42  ? 98.963  -21.004 -6.374  1.00 43.66  ?  4294 CYS   C O      1 
ATOM   5197 C  CB     . CYS   B  2 42  ? 100.480 -18.824 -8.137  1.00 43.94  ?  4294 CYS   C CB     1 
ATOM   5198 S  SG     . CYS   B  2 42  ? 101.843 -17.672 -7.932  1.00 46.84  ?  4294 CYS   C SG     1 
ATOM   5199 H  H      . CYS   B  2 42  ? 100.768 -18.305 -5.719  1.00 50.35  ?  4294 CYS   C H      1 
ATOM   5200 H  HA     . CYS   B  2 42  ? 98.786  -18.029 -7.357  1.00 55.47  ?  4294 CYS   C HA     1 
ATOM   5201 H  HB2    . CYS   B  2 42  ? 100.853 -19.719 -8.122  1.00 53.25  ?  4294 CYS   C HB2    1 
ATOM   5202 H  HB3    . CYS   B  2 42  ? 100.078 -18.646 -9.002  1.00 53.25  ?  4294 CYS   C HB3    1 
ATOM   5203 H  HG     . CYS   B  2 42  ? 102.079 -17.550 -6.762  1.00 56.73  ?  4294 CYS   C HG     1 
ATOM   5204 N  N      . VAL   B  2 43  ? 97.374  -19.958 -7.599  1.00 38.22  ?  4295 VAL   C N      1 
ATOM   5205 C  CA     . VAL   B  2 43  ? 96.305  -20.939 -7.440  1.00 42.34  ?  4295 VAL   C CA     1 
ATOM   5206 C  C      . VAL   B  2 43  ? 96.573  -22.070 -8.424  1.00 38.48  ?  4295 VAL   C C      1 
ATOM   5207 O  O      . VAL   B  2 43  ? 96.356  -21.917 -9.624  1.00 41.84  ?  4295 VAL   C O      1 
ATOM   5208 C  CB     . VAL   B  2 43  ? 94.935  -20.300 -7.678  1.00 38.96  ?  4295 VAL   C CB     1 
ATOM   5209 C  CG1    . VAL   B  2 43  ? 93.840  -21.341 -7.672  1.00 41.60  ?  4295 VAL   C CG1    1 
ATOM   5210 C  CG2    . VAL   B  2 43  ? 94.678  -19.208 -6.621  1.00 41.89  ?  4295 VAL   C CG2    1 
ATOM   5211 H  H      . VAL   B  2 43  ? 97.158  -19.326 -8.141  1.00 46.38  ?  4295 VAL   C H      1 
ATOM   5212 H  HA     . VAL   B  2 43  ? 96.330  -21.308 -6.544  1.00 51.32  ?  4295 VAL   C HA     1 
ATOM   5213 H  HB     . VAL   B  2 43  ? 94.925  -19.884 -8.554  1.00 47.27  ?  4295 VAL   C HB     1 
ATOM   5214 H  HG11   . VAL   B  2 43  ? 92.980  -20.895 -7.713  1.00 50.44  ?  4295 VAL   C HG11   1 
ATOM   5215 H  HG12   . VAL   B  2 43  ? 93.950  -21.919 -8.444  1.00 50.44  ?  4295 VAL   C HG12   1 
ATOM   5216 H  HG13   . VAL   B  2 43  ? 93.905  -21.863 -6.857  1.00 50.44  ?  4295 VAL   C HG13   1 
ATOM   5217 H  HG21   . VAL   B  2 43  ? 93.821  -18.790 -6.800  1.00 50.79  ?  4295 VAL   C HG21   1 
ATOM   5218 H  HG22   . VAL   B  2 43  ? 94.669  -19.616 -5.741  1.00 50.79  ?  4295 VAL   C HG22   1 
ATOM   5219 H  HG23   . VAL   B  2 43  ? 95.385  -18.546 -6.671  1.00 50.79  ?  4295 VAL   C HG23   1 
ATOM   5220 N  N      . LYS   B  2 44  ? 97.050  -23.205 -7.922  1.00 41.41  ?  4296 LYS   C N      1 
ATOM   5221 C  CA     . LYS   B  2 44  ? 97.309  -24.360 -8.756  1.00 42.81  ?  4296 LYS   C CA     1 
ATOM   5222 C  C      . LYS   B  2 44  ? 96.057  -25.221 -8.865  1.00 40.18  ?  4296 LYS   C C      1 
ATOM   5223 O  O      . LYS   B  2 44  ? 95.359  -25.465 -7.879  1.00 37.78  ?  4296 LYS   C O      1 
ATOM   5224 C  CB     . LYS   B  2 44  ? 98.460  -25.192 -8.197  1.00 41.51  ?  4296 LYS   C CB     1 
ATOM   5225 C  CG     . LYS   B  2 44  ? 98.946  -26.272 -9.154  1.00 43.81  ?  4296 LYS   C CG     1 
ATOM   5226 C  CD     . LYS   B  2 44  ? 100.326 -26.758 -8.784  1.00 40.15  ?  4296 LYS   C CD     1 
ATOM   5227 C  CE     . LYS   B  2 44  ? 100.252 -27.629 -7.538  1.00 42.93  ?  4296 LYS   C CE     1 
ATOM   5228 N  NZ     . LYS   B  2 44  ? 101.403 -28.587 -7.471  1.00 44.76  ?  4296 LYS   C NZ     1 
ATOM   5229 H  H      . LYS   B  2 44  ? 97.233  -23.327 -7.090  1.00 50.21  ?  4296 LYS   C H      1 
ATOM   5230 H  HA     . LYS   B  2 44  ? 97.558  -24.061 -9.644  1.00 51.89  ?  4296 LYS   C HA     1 
ATOM   5231 H  HB2    . LYS   B  2 44  ? 99.208  -24.604 -8.007  1.00 50.34  ?  4296 LYS   C HB2    1 
ATOM   5232 H  HB3    . LYS   B  2 44  ? 98.165  -25.627 -7.382  1.00 50.34  ?  4296 LYS   C HB3    1 
ATOM   5233 H  HG2    . LYS   B  2 44  ? 98.338  -27.028 -9.122  1.00 53.09  ?  4296 LYS   C HG2    1 
ATOM   5234 H  HG3    . LYS   B  2 44  ? 98.980  -25.913 -10.054 1.00 53.09  ?  4296 LYS   C HG3    1 
ATOM   5235 H  HD2    . LYS   B  2 44  ? 100.694 -27.284 -9.512  1.00 48.70  ?  4296 LYS   C HD2    1 
ATOM   5236 H  HD3    . LYS   B  2 44  ? 100.902 -25.999 -8.600  1.00 48.70  ?  4296 LYS   C HD3    1 
ATOM   5237 H  HE2    . LYS   B  2 44  ? 100.278 -27.065 -6.749  1.00 52.04  ?  4296 LYS   C HE2    1 
ATOM   5238 H  HE3    . LYS   B  2 44  ? 99.429  -28.142 -7.553  1.00 52.04  ?  4296 LYS   C HE3    1 
ATOM   5239 H  HZ1    . LYS   B  2 44  ? 101.130 -29.406 -7.688  1.00 54.24  ?  4296 LYS   C HZ1    1 
ATOM   5240 H  HZ2    . LYS   B  2 44  ? 102.041 -28.336 -8.037  1.00 54.24  ?  4296 LYS   C HZ2    1 
ATOM   5241 H  HZ3    . LYS   B  2 44  ? 101.738 -28.603 -6.646  1.00 54.24  ?  4296 LYS   C HZ3    1 
ATOM   5242 N  N      . MET   B  2 45  ? 95.784  -25.691 -10.074 1.00 39.38  ?  4297 MET   C N      1 
ATOM   5243 C  CA     . MET   B  2 45  ? 94.557  -26.423 -10.342 1.00 38.88  ?  4297 MET   C CA     1 
ATOM   5244 C  C      . MET   B  2 45  ? 94.817  -27.921 -10.351 1.00 36.57  ?  4297 MET   C C      1 
ATOM   5245 O  O      . MET   B  2 45  ? 95.927  -28.380 -10.632 1.00 45.02  ?  4297 MET   C O      1 
ATOM   5246 C  CB     . MET   B  2 45  ? 93.954  -26.015 -11.688 1.00 39.98  ?  4297 MET   C CB     1 
ATOM   5247 C  CG     . MET   B  2 45  ? 94.056  -24.522 -11.960 1.00 42.04  ?  4297 MET   C CG     1 
ATOM   5248 S  SD     . MET   B  2 45  ? 93.198  -23.509 -10.710 1.00 42.05  ?  4297 MET   C SD     1 
ATOM   5249 C  CE     . MET   B  2 45  ? 91.614  -24.322 -10.621 1.00 36.30  ?  4297 MET   C CE     1 
ATOM   5250 H  H      . MET   B  2 45  ? 96.298  -25.598 -10.758 1.00 47.78  ?  4297 MET   C H      1 
ATOM   5251 H  HA     . MET   B  2 45  ? 93.918  -26.212 -9.644  1.00 47.18  ?  4297 MET   C HA     1 
ATOM   5252 H  HB2    . MET   B  2 45  ? 94.425  -26.481 -12.397 1.00 48.50  ?  4297 MET   C HB2    1 
ATOM   5253 H  HB3    . MET   B  2 45  ? 93.015  -26.257 -11.697 1.00 48.50  ?  4297 MET   C HB3    1 
ATOM   5254 H  HG2    . MET   B  2 45  ? 94.992  -24.265 -11.962 1.00 50.97  ?  4297 MET   C HG2    1 
ATOM   5255 H  HG3    . MET   B  2 45  ? 93.658  -24.332 -12.824 1.00 50.97  ?  4297 MET   C HG3    1 
ATOM   5256 H  HE1    . MET   B  2 45  ? 91.029  -23.812 -10.040 1.00 44.09  ?  4297 MET   C HE1    1 
ATOM   5257 H  HE2    . MET   B  2 45  ? 91.234  -24.372 -11.512 1.00 44.09  ?  4297 MET   C HE2    1 
ATOM   5258 H  HE3    . MET   B  2 45  ? 91.738  -25.216 -10.264 1.00 44.09  ?  4297 MET   C HE3    1 
ATOM   5259 N  N      . LEU   B  2 46  ? 93.769  -28.676 -10.051 1.00 41.57  ?  4298 LEU   C N      1 
ATOM   5260 C  CA     . LEU   B  2 46  ? 93.752  -30.099 -10.335 1.00 40.07  ?  4298 LEU   C CA     1 
ATOM   5261 C  C      . LEU   B  2 46  ? 93.331  -30.306 -11.779 1.00 40.76  ?  4298 LEU   C C      1 
ATOM   5262 O  O      . LEU   B  2 46  ? 92.433  -29.629 -12.286 1.00 40.61  ?  4298 LEU   C O      1 
ATOM   5263 C  CB     . LEU   B  2 46  ? 92.795  -30.821 -9.399  1.00 40.52  ?  4298 LEU   C CB     1 
ATOM   5264 C  CG     . LEU   B  2 46  ? 93.248  -30.759 -7.947  1.00 38.60  ?  4298 LEU   C CG     1 
ATOM   5265 C  CD1    . LEU   B  2 46  ? 92.074  -30.976 -7.047  1.00 44.79  ?  4298 LEU   C CD1    1 
ATOM   5266 C  CD2    . LEU   B  2 46  ? 94.339  -31.799 -7.690  1.00 41.39  ?  4298 LEU   C CD2    1 
ATOM   5267 H  H      . LEU   B  2 46  ? 93.050  -28.384 -9.679  1.00 50.41  ?  4298 LEU   C H      1 
ATOM   5268 H  HA     . LEU   B  2 46  ? 94.633  -30.481 -10.200 1.00 48.61  ?  4298 LEU   C HA     1 
ATOM   5269 H  HB2    . LEU   B  2 46  ? 91.919  -30.408 -9.461  1.00 49.14  ?  4298 LEU   C HB2    1 
ATOM   5270 H  HB3    . LEU   B  2 46  ? 92.740  -31.754 -9.660  1.00 49.14  ?  4298 LEU   C HB3    1 
ATOM   5271 H  HG     . LEU   B  2 46  ? 93.624  -29.887 -7.752  1.00 46.85  ?  4298 LEU   C HG     1 
ATOM   5272 H  HD11   . LEU   B  2 46  ? 92.386  -31.032 -6.130  1.00 54.27  ?  4298 LEU   C HD11   1 
ATOM   5273 H  HD12   . LEU   B  2 46  ? 91.461  -30.231 -7.144  1.00 54.27  ?  4298 LEU   C HD12   1 
ATOM   5274 H  HD13   . LEU   B  2 46  ? 91.633  -31.803 -7.298  1.00 54.27  ?  4298 LEU   C HD13   1 
ATOM   5275 H  HD21   . LEU   B  2 46  ? 94.601  -31.758 -6.758  1.00 50.19  ?  4298 LEU   C HD21   1 
ATOM   5276 H  HD22   . LEU   B  2 46  ? 93.990  -32.680 -7.897  1.00 50.19  ?  4298 LEU   C HD22   1 
ATOM   5277 H  HD23   . LEU   B  2 46  ? 95.101  -31.604 -8.257  1.00 50.19  ?  4298 LEU   C HD23   1 
ATOM   5278 N  N      . CYS   B  2 47  ? 93.992  -31.241 -12.439 1.00 44.07  ?  4299 CYS   C N      1 
ATOM   5279 C  CA     . CYS   B  2 47  ? 93.778  -31.500 -13.854 1.00 44.74  ?  4299 CYS   C CA     1 
ATOM   5280 C  C      . CYS   B  2 47  ? 94.414  -32.837 -14.165 1.00 36.21  ?  4299 CYS   C C      1 
ATOM   5281 O  O      . CYS   B  2 47  ? 95.083  -33.436 -13.322 1.00 42.07  ?  4299 CYS   C O      1 
ATOM   5282 C  CB     . CYS   B  2 47  ? 94.365  -30.380 -14.717 1.00 41.73  ?  4299 CYS   C CB     1 
ATOM   5283 S  SG     . CYS   B  2 47  ? 96.114  -30.077 -14.440 1.00 41.38  ?  4299 CYS   C SG     1 
ATOM   5284 H  H      . CYS   B  2 47  ? 94.584  -31.753 -12.083 1.00 53.40  ?  4299 CYS   C H      1 
ATOM   5285 H  HA     . CYS   B  2 47  ? 92.830  -31.559 -14.049 1.00 54.21  ?  4299 CYS   C HA     1 
ATOM   5286 H  HB2    . CYS   B  2 47  ? 94.252  -30.617 -15.651 1.00 50.60  ?  4299 CYS   C HB2    1 
ATOM   5287 H  HB3    . CYS   B  2 47  ? 93.889  -29.558 -14.523 1.00 50.60  ?  4299 CYS   C HB3    1 
ATOM   5288 H  HG     . CYS   B  2 47  ? 96.488  -29.227 -15.200 1.00 50.18  ?  4299 CYS   C HG     1 
ATOM   5289 N  N      . THR   B  2 48  ? 94.194  -33.300 -15.390 1.00 47.85  ?  4300 THR   C N      1 
ATOM   5290 C  CA     . THR   B  2 48  ? 94.663  -34.627 -15.782 1.00 43.01  ?  4300 THR   C CA     1 
ATOM   5291 C  C      . THR   B  2 48  ? 96.160  -34.652 -16.048 1.00 41.84  ?  4300 THR   C C      1 
ATOM   5292 O  O      . THR   B  2 48  ? 96.781  -35.710 -15.915 1.00 43.80  ?  4300 THR   C O      1 
ATOM   5293 C  CB     . THR   B  2 48  ? 93.904  -35.081 -17.025 1.00 40.29  ?  4300 THR   C CB     1 
ATOM   5294 O  OG1    . THR   B  2 48  ? 94.078  -34.112 -18.065 1.00 49.69  ?  4300 THR   C OG1    1 
ATOM   5295 C  CG2    . THR   B  2 48  ? 92.437  -35.201 -16.717 1.00 52.49  ?  4300 THR   C CG2    1 
ATOM   5296 H  H      . THR   B  2 48  ? 93.779  -32.871 -16.009 1.00 57.94  ?  4300 THR   C H      1 
ATOM   5297 H  HA     . THR   B  2 48  ? 94.481  -35.261 -15.070 1.00 52.13  ?  4300 THR   C HA     1 
ATOM   5298 H  HB     . THR   B  2 48  ? 94.239  -35.943 -17.318 1.00 48.86  ?  4300 THR   C HB     1 
ATOM   5299 H  HG1    . THR   B  2 48  ? 93.681  -34.364 -18.762 1.00 60.15  ?  4300 THR   C HG1    1 
ATOM   5300 H  HG21   . THR   B  2 48  ? 91.976  -35.626 -17.457 1.00 63.51  ?  4300 THR   C HG21   1 
ATOM   5301 H  HG22   . THR   B  2 48  ? 92.309  -35.734 -15.917 1.00 63.51  ?  4300 THR   C HG22   1 
ATOM   5302 H  HG23   . THR   B  2 48  ? 92.056  -34.320 -16.572 1.00 63.51  ?  4300 THR   C HG23   1 
ATOM   5303 N  N      . HIS   B  2 49  ? 96.749  -33.508 -16.416 1.00 42.87  ?  4301 HIS   C N      1 
ATOM   5304 C  CA     . HIS   B  2 49  ? 98.118  -33.463 -16.911 1.00 45.53  ?  4301 HIS   C CA     1 
ATOM   5305 C  C      . HIS   B  2 49  ? 98.270  -34.305 -18.174 1.00 44.90  ?  4301 HIS   C C      1 
ATOM   5306 O  O      . HIS   B  2 49  ? 99.309  -34.928 -18.421 1.00 47.93  ?  4301 HIS   C O      1 
ATOM   5307 C  CB     . HIS   B  2 49  ? 99.075  -33.896 -15.818 1.00 44.05  ?  4301 HIS   C CB     1 
ATOM   5308 C  CG     . HIS   B  2 49  ? 99.019  -33.005 -14.623 1.00 40.42  ?  4301 HIS   C CG     1 
ATOM   5309 N  ND1    . HIS   B  2 49  ? 99.876  -31.940 -14.451 1.00 45.67  ?  4301 HIS   C ND1    1 
ATOM   5310 C  CD2    . HIS   B  2 49  ? 98.158  -32.969 -13.579 1.00 46.29  ?  4301 HIS   C CD2    1 
ATOM   5311 C  CE1    . HIS   B  2 49  ? 99.582  -31.320 -13.322 1.00 41.85  ?  4301 HIS   C CE1    1 
ATOM   5312 N  NE2    . HIS   B  2 49  ? 98.546  -31.928 -12.771 1.00 41.36  ?  4301 HIS   C NE2    1 
ATOM   5313 H  H      . HIS   B  2 49  ? 96.367  -32.738 -16.385 1.00 51.96  ?  4301 HIS   C H      1 
ATOM   5314 H  HA     . HIS   B  2 49  ? 98.348  -32.554 -17.163 1.00 55.16  ?  4301 HIS   C HA     1 
ATOM   5315 H  HB2    . HIS   B  2 49  ? 98.845  -34.795 -15.535 1.00 53.38  ?  4301 HIS   C HB2    1 
ATOM   5316 H  HB3    . HIS   B  2 49  ? 99.980  -33.879 -16.165 1.00 53.38  ?  4301 HIS   C HB3    1 
ATOM   5317 H  HD1    . HIS   B  2 49  ? 100.504 -31.714 -14.994 1.00 55.33  ?  4301 HIS   C HD1    1 
ATOM   5318 H  HD2    . HIS   B  2 49  ? 97.438  -33.541 -13.436 1.00 56.07  ?  4301 HIS   C HD2    1 
ATOM   5319 H  HE1    . HIS   B  2 49  ? 100.028 -30.582 -12.974 1.00 50.74  ?  4301 HIS   C HE1    1 
ATOM   5320 N  N      . THR   B  2 50  ? 97.224  -34.292 -19.001 1.00 43.33  ?  4302 THR   C N      1 
ATOM   5321 C  CA     . THR   B  2 50  ? 97.261  -34.886 -20.330 1.00 45.19  ?  4302 THR   C CA     1 
ATOM   5322 C  C      . THR   B  2 50  ? 96.741  -33.895 -21.356 1.00 51.78  ?  4302 THR   C C      1 
ATOM   5323 O  O      . THR   B  2 50  ? 96.139  -34.288 -22.361 1.00 52.24  ?  4302 THR   C O      1 
ATOM   5324 C  CB     . THR   B  2 50  ? 96.450  -36.178 -20.399 1.00 40.51  ?  4302 THR   C CB     1 
ATOM   5325 O  OG1    . THR   B  2 50  ? 95.055  -35.874 -20.293 1.00 45.53  ?  4302 THR   C OG1    1 
ATOM   5326 C  CG2    . THR   B  2 50  ? 96.867  -37.119 -19.283 1.00 39.08  ?  4302 THR   C CG2    1 
ATOM   5327 H  H      . THR   B  2 50  ? 96.466  -33.936 -18.807 1.00 52.51  ?  4302 THR   C H      1 
ATOM   5328 H  HA     . THR   B  2 50  ? 98.181  -35.111 -20.539 1.00 54.75  ?  4302 THR   C HA     1 
ATOM   5329 H  HB     . THR   B  2 50  ? 96.609  -36.625 -21.246 1.00 49.14  ?  4302 THR   C HB     1 
ATOM   5330 H  HG1    . THR   B  2 50  ? 94.599  -36.566 -20.431 1.00 55.16  ?  4302 THR   C HG1    1 
ATOM   5331 H  HG21   . THR   B  2 50  ? 96.443  -37.983 -19.402 1.00 47.42  ?  4302 THR   C HG21   1 
ATOM   5332 H  HG22   . THR   B  2 50  ? 97.830  -37.236 -19.291 1.00 47.42  ?  4302 THR   C HG22   1 
ATOM   5333 H  HG23   . THR   B  2 50  ? 96.601  -36.753 -18.424 1.00 47.42  ?  4302 THR   C HG23   1 
ATOM   5334 N  N      . GLY   B  2 51  ? 96.959  -32.602 -21.110 1.00 50.42  ?  4303 GLY   C N      1 
ATOM   5335 C  CA     . GLY   B  2 51  ? 96.529  -31.557 -22.009 1.00 45.81  ?  4303 GLY   C CA     1 
ATOM   5336 C  C      . GLY   B  2 51  ? 97.604  -31.163 -23.005 1.00 43.68  ?  4303 GLY   C C      1 
ATOM   5337 O  O      . GLY   B  2 51  ? 98.675  -31.761 -23.085 1.00 48.89  ?  4303 GLY   C O      1 
ATOM   5338 H  H      . GLY   B  2 51  ? 97.364  -32.309 -20.410 1.00 61.03  ?  4303 GLY   C H      1 
ATOM   5339 H  HA2    . GLY   B  2 51  ? 95.752  -31.860 -22.504 1.00 55.50  ?  4303 GLY   C HA2    1 
ATOM   5340 H  HA3    . GLY   B  2 51  ? 96.288  -30.771 -21.494 1.00 55.50  ?  4303 GLY   C HA3    1 
ATOM   5341 N  N      . THR   B  2 52  ? 97.305  -30.107 -23.760 1.00 48.61  ?  4304 THR   C N      1 
ATOM   5342 C  CA     . THR   B  2 52  ? 98.074  -29.736 -24.938 1.00 47.65  ?  4304 THR   C CA     1 
ATOM   5343 C  C      . THR   B  2 52  ? 99.437  -29.134 -24.622 1.00 46.87  ?  4304 THR   C C      1 
ATOM   5344 O  O      . THR   B  2 52  ? 100.265 -29.028 -25.533 1.00 51.35  ?  4304 THR   C O      1 
ATOM   5345 C  CB     . THR   B  2 52  ? 97.247  -28.758 -25.764 1.00 45.09  ?  4304 THR   C CB     1 
ATOM   5346 O  OG1    . THR   B  2 52  ? 97.167  -27.513 -25.064 1.00 50.73  ?  4304 THR   C OG1    1 
ATOM   5347 C  CG2    . THR   B  2 52  ? 95.841  -29.297 -25.960 1.00 47.23  ?  4304 THR   C CG2    1 
ATOM   5348 H  H      . THR   B  2 52  ? 96.645  -29.577 -23.605 1.00 58.86  ?  4304 THR   C H      1 
ATOM   5349 H  HA     . THR   B  2 52  ? 98.247  -30.531 -25.466 1.00 57.70  ?  4304 THR   C HA     1 
ATOM   5350 H  HB     . THR   B  2 52  ? 97.659  -28.627 -26.633 1.00 54.63  ?  4304 THR   C HB     1 
ATOM   5351 H  HG1    . THR   B  2 52  ? 96.704  -26.966 -25.503 1.00 61.40  ?  4304 THR   C HG1    1 
ATOM   5352 H  HG21   . THR   B  2 52  ? 95.411  -28.842 -26.702 1.00 57.19  ?  4304 THR   C HG21   1 
ATOM   5353 H  HG22   . THR   B  2 52  ? 95.874  -30.248 -26.151 1.00 57.19  ?  4304 THR   C HG22   1 
ATOM   5354 H  HG23   . THR   B  2 52  ? 95.316  -29.156 -25.157 1.00 57.19  ?  4304 THR   C HG23   1 
ATOM   5355 N  N      . GLY   B  2 53  ? 99.689  -28.735 -23.381 1.00 52.42  ?  4305 GLY   C N      1 
ATOM   5356 C  CA     . GLY   B  2 53  ? 100.950 -28.119 -23.045 1.00 45.81  ?  4305 GLY   C CA     1 
ATOM   5357 C  C      . GLY   B  2 53  ? 101.083 -26.679 -23.482 1.00 36.35  ?  4305 GLY   C C      1 
ATOM   5358 O  O      . GLY   B  2 53  ? 102.141 -26.086 -23.264 1.00 48.48  ?  4305 GLY   C O      1 
ATOM   5359 H  H      . GLY   B  2 53  ? 99.143  -28.813 -22.721 1.00 63.43  ?  4305 GLY   C H      1 
ATOM   5360 H  HA2    . GLY   B  2 53  ? 101.064 -28.149 -22.083 1.00 55.50  ?  4305 GLY   C HA2    1 
ATOM   5361 H  HA3    . GLY   B  2 53  ? 101.664 -28.623 -23.465 1.00 55.50  ?  4305 GLY   C HA3    1 
ATOM   5362 N  N      . GLN   B  2 54  ? 100.043 -26.091 -24.066 1.00 39.66  ?  4306 GLN   C N      1 
ATOM   5363 C  CA     . GLN   B  2 54  ? 100.115 -24.709 -24.506 1.00 43.27  ?  4306 GLN   C CA     1 
ATOM   5364 C  C      . GLN   B  2 54  ? 100.198 -23.756 -23.317 1.00 44.02  ?  4306 GLN   C C      1 
ATOM   5365 O  O      . GLN   B  2 54  ? 99.717  -24.041 -22.221 1.00 48.59  ?  4306 GLN   C O      1 
ATOM   5366 C  CB     . GLN   B  2 54  ? 98.902  -24.350 -25.343 1.00 48.53  ?  4306 GLN   C CB     1 
ATOM   5367 C  CG     . GLN   B  2 54  ? 98.866  -24.977 -26.677 1.00 58.85  ?  4306 GLN   C CG     1 
ATOM   5368 C  CD     . GLN   B  2 54  ? 97.778  -24.389 -27.549 1.00 57.62  ?  4306 GLN   C CD     1 
ATOM   5369 O  OE1    . GLN   B  2 54  ? 98.042  -23.801 -28.595 1.00 63.06  ?  4306 GLN   C OE1    1 
ATOM   5370 N  NE2    . GLN   B  2 54  ? 96.539  -24.518 -27.091 1.00 64.26  ?  4306 GLN   C NE2    1 
ATOM   5371 H  H      . GLN   B  2 54  ? 99.287  -26.472 -24.217 1.00 48.12  ?  4306 GLN   C H      1 
ATOM   5372 H  HA     . GLN   B  2 54  ? 100.913 -24.598 -25.048 1.00 52.45  ?  4306 GLN   C HA     1 
ATOM   5373 H  HB2    . GLN   B  2 54  ? 98.105  -24.631 -24.866 1.00 58.76  ?  4306 GLN   C HB2    1 
ATOM   5374 H  HB3    . GLN   B  2 54  ? 98.889  -23.389 -25.471 1.00 58.76  ?  4306 GLN   C HB3    1 
ATOM   5375 H  HG2    . GLN   B  2 54  ? 99.718  -24.837 -27.119 1.00 71.14  ?  4306 GLN   C HG2    1 
ATOM   5376 H  HG3    . GLN   B  2 54  ? 98.695  -25.927 -26.579 1.00 71.14  ?  4306 GLN   C HG3    1 
ATOM   5377 H  HE21   . GLN   B  2 54  ? 96.397  -24.916 -26.342 1.00 77.64  ?  4306 GLN   C HE21   1 
ATOM   5378 H  HE22   . GLN   B  2 54  ? 95.879  -24.203 -27.543 1.00 77.64  ?  4306 GLN   C HE22   1 
ATOM   5379 N  N      . ALA   B  2 55  ? 100.779 -22.580 -23.571 1.00 47.87  ?  4307 ALA   C N      1 
ATOM   5380 C  CA     . ALA   B  2 55  ? 101.167 -21.681 -22.489 1.00 47.00  ?  4307 ALA   C CA     1 
ATOM   5381 C  C      . ALA   B  2 55  ? 99.950  -21.152 -21.733 1.00 45.17  ?  4307 ALA   C C      1 
ATOM   5382 O  O      . ALA   B  2 55  ? 99.894  -21.228 -20.501 1.00 46.31  ?  4307 ALA   C O      1 
ATOM   5383 C  CB     . ALA   B  2 55  ? 102.001 -20.528 -23.045 1.00 45.75  ?  4307 ALA   C CB     1 
ATOM   5384 H  H      . ALA   B  2 55  ? 100.958 -22.283 -24.358 1.00 57.97  ?  4307 ALA   C H      1 
ATOM   5385 H  HA     . ALA   B  2 55  ? 101.712 -22.176 -21.857 1.00 56.92  ?  4307 ALA   C HA     1 
ATOM   5386 H  HB1    . ALA   B  2 55  ? 102.168 -19.888 -22.335 1.00 55.43  ?  4307 ALA   C HB1    1 
ATOM   5387 H  HB2    . ALA   B  2 55  ? 102.842 -20.878 -23.379 1.00 55.43  ?  4307 ALA   C HB2    1 
ATOM   5388 H  HB3    . ALA   B  2 55  ? 101.511 -20.102 -23.766 1.00 55.43  ?  4307 ALA   C HB3    1 
ATOM   5389 N  N      . ILE   B  2 56  ? 98.985  -20.576 -22.447 1.00 46.45  ?  4308 ILE   C N      1 
ATOM   5390 C  CA     . ILE   B  2 56  ? 97.881  -19.846 -21.834 1.00 43.27  ?  4308 ILE   C CA     1 
ATOM   5391 C  C      . ILE   B  2 56  ? 96.593  -20.299 -22.501 1.00 40.85  ?  4308 ILE   C C      1 
ATOM   5392 O  O      . ILE   B  2 56  ? 96.439  -20.149 -23.717 1.00 51.83  ?  4308 ILE   C O      1 
ATOM   5393 C  CB     . ILE   B  2 56  ? 98.056  -18.326 -21.968 1.00 45.78  ?  4308 ILE   C CB     1 
ATOM   5394 C  CG1    . ILE   B  2 56  ? 99.369  -17.919 -21.290 1.00 46.78  ?  4308 ILE   C CG1    1 
ATOM   5395 C  CG2    . ILE   B  2 56  ? 96.857  -17.624 -21.364 1.00 47.27  ?  4308 ILE   C CG2    1 
ATOM   5396 C  CD1    . ILE   B  2 56  ? 99.745  -16.465 -21.501 1.00 44.73  ?  4308 ILE   C CD1    1 
ATOM   5397 H  H      . ILE   B  2 56  ? 98.949  -20.596 -23.306 1.00 56.26  ?  4308 ILE   C H      1 
ATOM   5398 H  HA     . ILE   B  2 56  ? 97.824  -20.065 -20.891 1.00 52.45  ?  4308 ILE   C HA     1 
ATOM   5399 H  HB     . ILE   B  2 56  ? 98.106  -18.066 -22.901 1.00 55.46  ?  4308 ILE   C HB     1 
ATOM   5400 H  HG12   . ILE   B  2 56  ? 99.285  -18.067 -20.335 1.00 56.66  ?  4308 ILE   C HG12   1 
ATOM   5401 H  HG13   . ILE   B  2 56  ? 100.086 -18.465 -21.649 1.00 56.66  ?  4308 ILE   C HG13   1 
ATOM   5402 H  HG21   . ILE   B  2 56  ? 97.083  -16.695 -21.201 1.00 57.24  ?  4308 ILE   C HG21   1 
ATOM   5403 H  HG22   . ILE   B  2 56  ? 96.113  -17.680 -21.985 1.00 57.24  ?  4308 ILE   C HG22   1 
ATOM   5404 H  HG23   . ILE   B  2 56  ? 96.624  -18.059 -20.529 1.00 57.24  ?  4308 ILE   C HG23   1 
ATOM   5405 H  HD11   . ILE   B  2 56  ? 100.642 -16.318 -21.163 1.00 54.20  ?  4308 ILE   C HD11   1 
ATOM   5406 H  HD12   . ILE   B  2 56  ? 99.712  -16.265 -22.450 1.00 54.20  ?  4308 ILE   C HD12   1 
ATOM   5407 H  HD13   . ILE   B  2 56  ? 99.115  -15.904 -21.023 1.00 54.20  ?  4308 ILE   C HD13   1 
ATOM   5408 N  N      . THR   B  2 57  ? 95.658  -20.827 -21.712 1.00 44.77  ?  4309 THR   C N      1 
ATOM   5409 C  CA     . THR   B  2 57  ? 94.516  -21.541 -22.262 1.00 44.24  ?  4309 THR   C CA     1 
ATOM   5410 C  C      . THR   B  2 57  ? 93.274  -21.222 -21.450 1.00 45.07  ?  4309 THR   C C      1 
ATOM   5411 O  O      . THR   B  2 57  ? 93.348  -20.725 -20.320 1.00 45.02  ?  4309 THR   C O      1 
ATOM   5412 C  CB     . THR   B  2 57  ? 94.778  -23.044 -22.267 1.00 37.88  ?  4309 THR   C CB     1 
ATOM   5413 O  OG1    . THR   B  2 57  ? 95.093  -23.477 -20.939 1.00 42.89  ?  4309 THR   C OG1    1 
ATOM   5414 C  CG2    . THR   B  2 57  ? 95.970  -23.357 -23.168 1.00 46.44  ?  4309 THR   C CG2    1 
ATOM   5415 H  H      . THR   B  2 57  ? 95.666  -20.784 -20.853 1.00 54.24  ?  4309 THR   C H      1 
ATOM   5416 H  HA     . THR   B  2 57  ? 94.349  -21.246 -23.171 1.00 53.61  ?  4309 THR   C HA     1 
ATOM   5417 H  HB     . THR   B  2 57  ? 93.993  -23.512 -22.591 1.00 45.97  ?  4309 THR   C HB     1 
ATOM   5418 H  HG1    . THR   B  2 57  ? 95.179  -24.313 -20.922 1.00 51.98  ?  4309 THR   C HG1    1 
ATOM   5419 H  HG21   . THR   B  2 57  ? 96.041  -24.315 -23.303 1.00 56.25  ?  4309 THR   C HG21   1 
ATOM   5420 H  HG22   . THR   B  2 57  ? 95.857  -22.926 -24.030 1.00 56.25  ?  4309 THR   C HG22   1 
ATOM   5421 H  HG23   . THR   B  2 57  ? 96.789  -23.035 -22.760 1.00 56.25  ?  4309 THR   C HG23   1 
ATOM   5422 N  N      . VAL   B  2 58  ? 92.120  -21.525 -22.046 1.00 41.28  ?  4310 VAL   C N      1 
ATOM   5423 C  CA     . VAL   B  2 58  ? 90.853  -21.163 -21.416 1.00 47.44  ?  4310 VAL   C CA     1 
ATOM   5424 C  C      . VAL   B  2 58  ? 90.446  -22.159 -20.338 1.00 41.97  ?  4310 VAL   C C      1 
ATOM   5425 O  O      . VAL   B  2 58  ? 89.512  -21.896 -19.574 1.00 45.14  ?  4310 VAL   C O      1 
ATOM   5426 C  CB     . VAL   B  2 58  ? 89.708  -21.072 -22.445 1.00 45.86  ?  4310 VAL   C CB     1 
ATOM   5427 C  CG1    . VAL   B  2 58  ? 89.979  -20.018 -23.490 1.00 47.02  ?  4310 VAL   C CG1    1 
ATOM   5428 C  CG2    . VAL   B  2 58  ? 89.489  -22.458 -23.103 1.00 51.77  ?  4310 VAL   C CG2    1 
ATOM   5429 H  H      . VAL   B  2 58  ? 92.045  -21.931 -22.800 1.00 50.06  ?  4310 VAL   C H      1 
ATOM   5430 H  HA     . VAL   B  2 58  ? 90.981  -20.289 -21.016 1.00 57.44  ?  4310 VAL   C HA     1 
ATOM   5431 H  HB     . VAL   B  2 58  ? 88.896  -20.808 -21.985 1.00 55.56  ?  4310 VAL   C HB     1 
ATOM   5432 H  HG11   . VAL   B  2 58  ? 89.213  -19.956 -24.082 1.00 56.95  ?  4310 VAL   C HG11   1 
ATOM   5433 H  HG12   . VAL   B  2 58  ? 90.127  -19.167 -23.049 1.00 56.95  ?  4310 VAL   C HG12   1 
ATOM   5434 H  HG13   . VAL   B  2 58  ? 90.768  -20.270 -23.996 1.00 56.95  ?  4310 VAL   C HG13   1 
ATOM   5435 H  HG21   . VAL   B  2 58  ? 88.829  -22.372 -23.809 1.00 62.64  ?  4310 VAL   C HG21   1 
ATOM   5436 H  HG22   . VAL   B  2 58  ? 90.330  -22.770 -23.472 1.00 62.64  ?  4310 VAL   C HG22   1 
ATOM   5437 H  HG23   . VAL   B  2 58  ? 89.172  -23.080 -22.429 1.00 62.64  ?  4310 VAL   C HG23   1 
ATOM   5438 N  N      . THR   B  2 59  ? 91.089  -23.311 -20.291 1.00 46.50  ?  4311 THR   C N      1 
ATOM   5439 C  CA     . THR   B  2 59  ? 90.882  -24.365 -19.313 1.00 43.89  ?  4311 THR   C CA     1 
ATOM   5440 C  C      . THR   B  2 59  ? 92.249  -24.980 -19.074 1.00 39.94  ?  4311 THR   C C      1 
ATOM   5441 O  O      . THR   B  2 59  ? 93.139  -24.860 -19.923 1.00 45.27  ?  4311 THR   C O      1 
ATOM   5442 C  CB     . THR   B  2 59  ? 89.878  -25.421 -19.792 1.00 44.80  ?  4311 THR   C CB     1 
ATOM   5443 O  OG1    . THR   B  2 59  ? 89.366  -26.142 -18.661 1.00 48.48  ?  4311 THR   C OG1    1 
ATOM   5444 C  CG2    . THR   B  2 59  ? 90.507  -26.363 -20.793 1.00 51.69  ?  4311 THR   C CG2    1 
ATOM   5445 H  H      . THR   B  2 59  ? 91.699  -23.523 -20.859 1.00 56.32  ?  4311 THR   C H      1 
ATOM   5446 H  HA     . THR   B  2 59  ? 90.523  -24.015 -18.482 1.00 53.19  ?  4311 THR   C HA     1 
ATOM   5447 H  HB     . THR   B  2 59  ? 89.139  -24.986 -20.245 1.00 54.28  ?  4311 THR   C HB     1 
ATOM   5448 H  HG1    . THR   B  2 59  ? 88.810  -26.718 -18.915 1.00 58.70  ?  4311 THR   C HG1    1 
ATOM   5449 H  HG21   . THR   B  2 59  ? 89.816  -26.841 -21.278 1.00 62.55  ?  4311 THR   C HG21   1 
ATOM   5450 H  HG22   . THR   B  2 59  ? 91.046  -25.863 -21.425 1.00 62.55  ?  4311 THR   C HG22   1 
ATOM   5451 H  HG23   . THR   B  2 59  ? 91.072  -27.004 -20.335 1.00 62.55  ?  4311 THR   C HG23   1 
ATOM   5452 N  N      . PRO   B  2 60  ? 92.466  -25.600 -17.912 1.00 40.31  ?  4312 PRO   C N      1 
ATOM   5453 C  CA     . PRO   B  2 60  ? 93.779  -26.194 -17.627 1.00 40.25  ?  4312 PRO   C CA     1 
ATOM   5454 C  C      . PRO   B  2 60  ? 94.196  -27.189 -18.701 1.00 39.02  ?  4312 PRO   C C      1 
ATOM   5455 O  O      . PRO   B  2 60  ? 93.440  -28.089 -19.070 1.00 49.67  ?  4312 PRO   C O      1 
ATOM   5456 C  CB     . PRO   B  2 60  ? 93.568  -26.876 -16.273 1.00 39.59  ?  4312 PRO   C CB     1 
ATOM   5457 C  CG     . PRO   B  2 60  ? 92.543  -26.030 -15.601 1.00 40.49  ?  4312 PRO   C CG     1 
ATOM   5458 C  CD     . PRO   B  2 60  ? 91.602  -25.594 -16.716 1.00 40.46  ?  4312 PRO   C CD     1 
ATOM   5459 H  HA     . PRO   B  2 60  ? 94.456  -25.503 -17.551 1.00 48.82  ?  4312 PRO   C HA     1 
ATOM   5460 H  HB2    . PRO   B  2 60  ? 93.245  -27.782 -16.402 1.00 48.03  ?  4312 PRO   C HB2    1 
ATOM   5461 H  HB3    . PRO   B  2 60  ? 94.397  -26.887 -15.771 1.00 48.03  ?  4312 PRO   C HB3    1 
ATOM   5462 H  HG2    . PRO   B  2 60  ? 92.071  -26.550 -14.932 1.00 49.11  ?  4312 PRO   C HG2    1 
ATOM   5463 H  HG3    . PRO   B  2 60  ? 92.968  -25.263 -15.186 1.00 49.11  ?  4312 PRO   C HG3    1 
ATOM   5464 H  HD2    . PRO   B  2 60  ? 90.870  -26.223 -16.816 1.00 49.08  ?  4312 PRO   C HD2    1 
ATOM   5465 H  HD3    . PRO   B  2 60  ? 91.254  -24.704 -16.546 1.00 49.08  ?  4312 PRO   C HD3    1 
ATOM   5466 N  N      . GLU   B  2 61  ? 95.434  -27.034 -19.181 1.00 46.24  ?  4313 GLU   C N      1 
ATOM   5467 C  CA     . GLU   B  2 61  ? 95.943  -27.848 -20.275 1.00 43.69  ?  4313 GLU   C CA     1 
ATOM   5468 C  C      . GLU   B  2 61  ? 97.315  -28.424 -19.949 1.00 41.36  ?  4313 GLU   C C      1 
ATOM   5469 O  O      . GLU   B  2 61  ? 98.043  -28.827 -20.861 1.00 48.25  ?  4313 GLU   C O      1 
ATOM   5470 C  CB     . GLU   B  2 61  ? 96.016  -27.015 -21.558 1.00 42.75  ?  4313 GLU   C CB     1 
ATOM   5471 C  CG     . GLU   B  2 61  ? 94.656  -26.772 -22.203 1.00 38.16  ?  4313 GLU   C CG     1 
ATOM   5472 C  CD     . GLU   B  2 61  ? 94.014  -28.026 -22.728 1.00 38.19  ?  4313 GLU   C CD     1 
ATOM   5473 O  OE1    . GLU   B  2 61  ? 94.650  -29.090 -22.717 1.00 46.91  ?  4313 GLU   C OE1    1 
ATOM   5474 O  OE2    . GLU   B  2 61  ? 92.844  -27.960 -23.138 1.00 44.90  ?  4313 GLU   C OE2    1 
ATOM   5475 H  H      . GLU   B  2 61  ? 95.999  -26.458 -18.883 1.00 56.01  ?  4313 GLU   C H      1 
ATOM   5476 H  HA     . GLU   B  2 61  ? 95.339  -28.591 -20.427 1.00 52.95  ?  4313 GLU   C HA     1 
ATOM   5477 H  HB2    . GLU   B  2 61  ? 96.404  -26.151 -21.349 1.00 51.82  ?  4313 GLU   C HB2    1 
ATOM   5478 H  HB3    . GLU   B  2 61  ? 96.571  -27.482 -22.203 1.00 51.82  ?  4313 GLU   C HB3    1 
ATOM   5479 H  HG2    . GLU   B  2 61  ? 94.059  -26.387 -21.543 1.00 46.31  ?  4313 GLU   C HG2    1 
ATOM   5480 H  HG3    . GLU   B  2 61  ? 94.766  -26.160 -22.948 1.00 46.31  ?  4313 GLU   C HG3    1 
ATOM   5481 N  N      . ALA   B  2 62  ? 97.686  -28.464 -18.673 1.00 41.00  ?  4314 ALA   C N      1 
ATOM   5482 C  CA     . ALA   B  2 62  ? 98.995  -28.963 -18.290 1.00 41.33  ?  4314 ALA   C CA     1 
ATOM   5483 C  C      . ALA   B  2 62  ? 99.202  -30.354 -18.867 1.00 48.89  ?  4314 ALA   C C      1 
ATOM   5484 O  O      . ALA   B  2 62  ? 98.265  -31.149 -18.963 1.00 44.22  ?  4314 ALA   C O      1 
ATOM   5485 C  CB     . ALA   B  2 62  ? 99.128  -29.002 -16.767 1.00 41.24  ?  4314 ALA   C CB     1 
ATOM   5486 H  H      . ALA   B  2 62  ? 97.197  -28.207 -18.014 1.00 49.73  ?  4314 ALA   C H      1 
ATOM   5487 H  HA     . ALA   B  2 62  ? 99.684  -28.372 -18.632 1.00 50.12  ?  4314 ALA   C HA     1 
ATOM   5488 H  HB1    . ALA   B  2 62  ? 100.002 -29.353 -16.535 1.00 50.01  ?  4314 ALA   C HB1    1 
ATOM   5489 H  HB2    . ALA   B  2 62  ? 99.030  -28.102 -16.418 1.00 50.01  ?  4314 ALA   C HB2    1 
ATOM   5490 H  HB3    . ALA   B  2 62  ? 98.434  -29.575 -16.404 1.00 50.01  ?  4314 ALA   C HB3    1 
ATOM   5491 N  N      . ASN   B  2 63  ? 100.433 -30.633 -19.267 1.00 47.53  ?  4315 ASN   C N      1 
ATOM   5492 C  CA     . ASN   B  2 63  ? 100.857 -31.963 -19.645 1.00 47.52  ?  4315 ASN   C CA     1 
ATOM   5493 C  C      . ASN   B  2 63  ? 101.613 -32.597 -18.485 1.00 48.15  ?  4315 ASN   C C      1 
ATOM   5494 O  O      . ASN   B  2 63  ? 101.603 -32.092 -17.355 1.00 49.34  ?  4315 ASN   C O      1 
ATOM   5495 C  CB     . ASN   B  2 63  ? 101.697 -31.898 -20.922 1.00 49.84  ?  4315 ASN   C CB     1 
ATOM   5496 C  CG     . ASN   B  2 63  ? 103.021 -31.204 -20.713 1.00 45.59  ?  4315 ASN   C CG     1 
ATOM   5497 O  OD1    . ASN   B  2 63  ? 103.585 -31.212 -19.618 1.00 52.85  ?  4315 ASN   C OD1    1 
ATOM   5498 N  ND2    . ASN   B  2 63  ? 103.533 -30.603 -21.772 1.00 45.45  ?  4315 ASN   C ND2    1 
ATOM   5499 H  H      . ASN   B  2 63  ? 101.059 -30.046 -19.330 1.00 57.56  ?  4315 ASN   C H      1 
ATOM   5500 H  HA     . ASN   B  2 63  ? 100.075 -32.506 -19.833 1.00 57.55  ?  4315 ASN   C HA     1 
ATOM   5501 H  HB2    . ASN   B  2 63  ? 101.876 -32.801 -21.228 1.00 60.33  ?  4315 ASN   C HB2    1 
ATOM   5502 H  HB3    . ASN   B  2 63  ? 101.205 -31.409 -21.599 1.00 60.33  ?  4315 ASN   C HB3    1 
ATOM   5503 H  HD21   . ASN   B  2 63  ? 104.286 -30.192 -21.711 1.00 55.06  ?  4315 ASN   C HD21   1 
ATOM   5504 H  HD22   . ASN   B  2 63  ? 103.113 -30.622 -22.523 1.00 55.06  ?  4315 ASN   C HD22   1 
ATOM   5505 N  N      . MET   B  2 64  ? 102.307 -33.696 -18.780 1.00 49.12  ?  4316 MET   C N      1 
ATOM   5506 C  CA     . MET   B  2 64  ? 103.002 -34.441 -17.743 1.00 46.25  ?  4316 MET   C CA     1 
ATOM   5507 C  C      . MET   B  2 64  ? 104.049 -33.597 -17.039 1.00 48.81  ?  4316 MET   C C      1 
ATOM   5508 O  O      . MET   B  2 64  ? 104.393 -33.879 -15.884 1.00 53.60  ?  4316 MET   C O      1 
ATOM   5509 C  CB     . MET   B  2 64  ? 103.663 -35.680 -18.353 1.00 55.92  ?  4316 MET   C CB     1 
ATOM   5510 C  CG     . MET   B  2 64  ? 104.384 -36.571 -17.370 1.00 59.76  ?  4316 MET   C CG     1 
ATOM   5511 S  SD     . MET   B  2 64  ? 104.260 -38.329 -17.754 1.00 68.73  ?  4316 MET   C SD     1 
ATOM   5512 C  CE     . MET   B  2 64  ? 105.882 -38.685 -18.423 1.00 60.69  ?  4316 MET   C CE     1 
ATOM   5513 H  H      . MET   B  2 64  ? 102.389 -34.027 -19.570 1.00 59.46  ?  4316 MET   C H      1 
ATOM   5514 H  HA     . MET   B  2 64  ? 102.347 -34.730 -17.089 1.00 56.02  ?  4316 MET   C HA     1 
ATOM   5515 H  HB2    . MET   B  2 64  ? 102.975 -36.215 -18.780 1.00 67.62  ?  4316 MET   C HB2    1 
ATOM   5516 H  HB3    . MET   B  2 64  ? 104.312 -35.388 -19.011 1.00 67.62  ?  4316 MET   C HB3    1 
ATOM   5517 H  HG2    . MET   B  2 64  ? 105.325 -36.334 -17.366 1.00 72.23  ?  4316 MET   C HG2    1 
ATOM   5518 H  HG3    . MET   B  2 64  ? 104.004 -36.433 -16.488 1.00 72.23  ?  4316 MET   C HG3    1 
ATOM   5519 H  HE1    . MET   B  2 64  ? 105.918 -39.619 -18.683 1.00 73.35  ?  4316 MET   C HE1    1 
ATOM   5520 H  HE2    . MET   B  2 64  ? 106.035 -38.120 -19.197 1.00 73.35  ?  4316 MET   C HE2    1 
ATOM   5521 H  HE3    . MET   B  2 64  ? 106.550 -38.504 -17.745 1.00 73.35  ?  4316 MET   C HE3    1 
ATOM   5522 N  N      . ASP   B  2 65  ? 104.581 -32.581 -17.711 1.00 45.95  ?  4317 ASP   C N      1 
ATOM   5523 C  CA     . ASP   B  2 65  ? 105.713 -31.825 -17.195 1.00 51.89  ?  4317 ASP   C CA     1 
ATOM   5524 C  C      . ASP   B  2 65  ? 105.320 -30.400 -16.832 1.00 49.23  ?  4317 ASP   C C      1 
ATOM   5525 O  O      . ASP   B  2 65  ? 106.180 -29.518 -16.739 1.00 55.88  ?  4317 ASP   C O      1 
ATOM   5526 C  CB     . ASP   B  2 65  ? 106.847 -31.809 -18.212 1.00 55.45  ?  4317 ASP   C CB     1 
ATOM   5527 C  CG     . ASP   B  2 65  ? 107.282 -33.183 -18.617 1.00 56.84  ?  4317 ASP   C CG     1 
ATOM   5528 O  OD1    . ASP   B  2 65  ? 107.706 -33.962 -17.753 1.00 60.39  ?  4317 ASP   C OD1    1 
ATOM   5529 O  OD2    . ASP   B  2 65  ? 107.166 -33.501 -19.808 1.00 52.01  ?  4317 ASP   C OD2    1 
ATOM   5530 H  H      . ASP   B  2 65  ? 104.299 -32.308 -18.477 1.00 55.67  ?  4317 ASP   C H      1 
ATOM   5531 H  HA     . ASP   B  2 65  ? 106.038 -32.264 -16.393 1.00 62.79  ?  4317 ASP   C HA     1 
ATOM   5532 H  HB2    . ASP   B  2 65  ? 106.550 -31.341 -19.009 1.00 67.06  ?  4317 ASP   C HB2    1 
ATOM   5533 H  HB3    . ASP   B  2 65  ? 107.612 -31.354 -17.826 1.00 67.06  ?  4317 ASP   C HB3    1 
ATOM   5534 N  N      . GLN   B  2 66  ? 104.033 -30.154 -16.619 1.00 49.97  ?  4318 GLN   C N      1 
ATOM   5535 C  CA     . GLN   B  2 66  ? 103.541 -28.824 -16.308 1.00 44.51  ?  4318 GLN   C CA     1 
ATOM   5536 C  C      . GLN   B  2 66  ? 102.549 -28.899 -15.160 1.00 46.76  ?  4318 GLN   C C      1 
ATOM   5537 O  O      . GLN   B  2 66  ? 101.916 -29.929 -14.915 1.00 47.53  ?  4318 GLN   C O      1 
ATOM   5538 C  CB     . GLN   B  2 66  ? 102.833 -28.165 -17.498 1.00 44.23  ?  4318 GLN   C CB     1 
ATOM   5539 C  CG     . GLN   B  2 66  ? 103.642 -28.031 -18.769 1.00 45.55  ?  4318 GLN   C CG     1 
ATOM   5540 C  CD     . GLN   B  2 66  ? 102.782 -27.627 -19.916 1.00 39.95  ?  4318 GLN   C CD     1 
ATOM   5541 O  OE1    . GLN   B  2 66  ? 101.633 -28.043 -19.992 1.00 50.15  ?  4318 GLN   C OE1    1 
ATOM   5542 N  NE2    . GLN   B  2 66  ? 103.314 -26.815 -20.817 1.00 46.94  ?  4318 GLN   C NE2    1 
ATOM   5543 H  H      . GLN   B  2 66  ? 103.417 -30.753 -16.651 1.00 60.48  ?  4318 GLN   C H      1 
ATOM   5544 H  HA     . GLN   B  2 66  ? 104.302 -28.280 -16.050 1.00 53.93  ?  4318 GLN   C HA     1 
ATOM   5545 H  HB2    . GLN   B  2 66  ? 102.049 -28.694 -17.714 1.00 53.59  ?  4318 GLN   C HB2    1 
ATOM   5546 H  HB3    . GLN   B  2 66  ? 102.568 -27.270 -17.234 1.00 53.59  ?  4318 GLN   C HB3    1 
ATOM   5547 H  HG2    . GLN   B  2 66  ? 104.326 -27.355 -18.645 1.00 55.19  ?  4318 GLN   C HG2    1 
ATOM   5548 H  HG3    . GLN   B  2 66  ? 104.053 -28.884 -18.980 1.00 55.19  ?  4318 GLN   C HG3    1 
ATOM   5549 H  HE21   . GLN   B  2 66  ? 104.124 -26.543 -20.726 1.00 56.86  ?  4318 GLN   C HE21   1 
ATOM   5550 H  HE22   . GLN   B  2 66  ? 102.848 -26.559 -21.494 1.00 56.86  ?  4318 GLN   C HE22   1 
ATOM   5551 N  N      . GLU   B  2 67  ? 102.417 -27.779 -14.463 1.00 51.41  ?  4319 GLU   C N      1 
ATOM   5552 C  CA     . GLU   B  2 67  ? 101.305 -27.518 -13.567 1.00 41.16  ?  4319 GLU   C CA     1 
ATOM   5553 C  C      . GLU   B  2 67  ? 100.438 -26.443 -14.200 1.00 38.06  ?  4319 GLU   C C      1 
ATOM   5554 O  O      . GLU   B  2 67  ? 100.930 -25.588 -14.942 1.00 44.22  ?  4319 GLU   C O      1 
ATOM   5555 C  CB     . GLU   B  2 67  ? 101.786 -27.072 -12.188 1.00 40.22  ?  4319 GLU   C CB     1 
ATOM   5556 C  CG     . GLU   B  2 67  ? 102.724 -28.072 -11.530 1.00 42.20  ?  4319 GLU   C CG     1 
ATOM   5557 C  CD     . GLU   B  2 67  ? 101.991 -29.113 -10.729 1.00 42.92  ?  4319 GLU   C CD     1 
ATOM   5558 O  OE1    . GLU   B  2 67  ? 100.864 -29.480 -11.119 1.00 46.10  ?  4319 GLU   C OE1    1 
ATOM   5559 O  OE2    . GLU   B  2 67  ? 102.520 -29.532 -9.684  1.00 50.22  ?  4319 GLU   C OE2    1 
ATOM   5560 H  H      . GLU   B  2 67  ? 102.982 -27.131 -14.495 1.00 62.22  ?  4319 GLU   C H      1 
ATOM   5561 H  HA     . GLU   B  2 67  ? 100.778 -28.321 -13.431 1.00 49.92  ?  4319 GLU   C HA     1 
ATOM   5562 H  HB2    . GLU   B  2 67  ? 102.260 -26.231 -12.277 1.00 48.79  ?  4319 GLU   C HB2    1 
ATOM   5563 H  HB3    . GLU   B  2 67  ? 101.016 -26.959 -11.608 1.00 48.79  ?  4319 GLU   C HB3    1 
ATOM   5564 H  HG2    . GLU   B  2 67  ? 103.234 -28.527 -12.218 1.00 51.16  ?  4319 GLU   C HG2    1 
ATOM   5565 H  HG3    . GLU   B  2 67  ? 103.322 -27.598 -10.932 1.00 51.16  ?  4319 GLU   C HG3    1 
ATOM   5566 N  N      . SER   B  2 68  ? 99.146  -26.498 -13.919 1.00 45.49  ?  4320 SER   C N      1 
ATOM   5567 C  CA     . SER   B  2 68  ? 98.220  -25.475 -14.375 1.00 40.25  ?  4320 SER   C CA     1 
ATOM   5568 C  C      . SER   B  2 68  ? 97.863  -24.561 -13.214 1.00 39.51  ?  4320 SER   C C      1 
ATOM   5569 O  O      . SER   B  2 68  ? 97.630  -25.020 -12.092 1.00 42.49  ?  4320 SER   C O      1 
ATOM   5570 C  CB     . SER   B  2 68  ? 96.955  -26.079 -14.978 1.00 42.27  ?  4320 SER   C CB     1 
ATOM   5571 O  OG     . SER   B  2 68  ? 97.213  -26.555 -16.288 1.00 40.14  ?  4320 SER   C OG     1 
ATOM   5572 H  H      . SER   B  2 68  ? 98.777  -27.125 -13.461 1.00 55.11  ?  4320 SER   C H      1 
ATOM   5573 H  HA     . SER   B  2 68  ? 98.643  -24.949 -15.071 1.00 48.82  ?  4320 SER   C HA     1 
ATOM   5574 H  HB2    . SER   B  2 68  ? 96.661  -26.818 -14.423 1.00 51.25  ?  4320 SER   C HB2    1 
ATOM   5575 H  HB3    . SER   B  2 68  ? 96.266  -25.398 -15.017 1.00 51.25  ?  4320 SER   C HB3    1 
ATOM   5576 H  HG     . SER   B  2 68  ? 97.452  -25.919 -16.783 1.00 48.69  ?  4320 SER   C HG     1 
ATOM   5577 N  N      . PHE   B  2 69  ? 97.847  -23.259 -13.479 1.00 49.31  ?  4321 PHE   C N      1 
ATOM   5578 C  CA     . PHE   B  2 69  ? 97.480  -22.272 -12.471 1.00 39.13  ?  4321 PHE   C CA     1 
ATOM   5579 C  C      . PHE   B  2 69  ? 96.412  -21.333 -13.015 1.00 37.65  ?  4321 PHE   C C      1 
ATOM   5580 O  O      . PHE   B  2 69  ? 96.373  -21.049 -14.212 1.00 39.91  ?  4321 PHE   C O      1 
ATOM   5581 C  CB     . PHE   B  2 69  ? 98.671  -21.394 -12.033 1.00 35.35  ?  4321 PHE   C CB     1 
ATOM   5582 C  CG     . PHE   B  2 69  ? 99.750  -22.126 -11.329 1.00 38.83  ?  4321 PHE   C CG     1 
ATOM   5583 C  CD1    . PHE   B  2 69  ? 100.723 -22.783 -12.049 1.00 40.88  ?  4321 PHE   C CD1    1 
ATOM   5584 C  CD2    . PHE   B  2 69  ? 99.824  -22.132 -9.953  1.00 38.05  ?  4321 PHE   C CD2    1 
ATOM   5585 C  CE1    . PHE   B  2 69  ? 101.725 -23.467 -11.404 1.00 39.82  ?  4321 PHE   C CE1    1 
ATOM   5586 C  CE2    . PHE   B  2 69  ? 100.821 -22.807 -9.316  1.00 41.16  ?  4321 PHE   C CE2    1 
ATOM   5587 C  CZ     . PHE   B  2 69  ? 101.779 -23.463 -10.039 1.00 40.81  ?  4321 PHE   C CZ     1 
ATOM   5588 H  H      . PHE   B  2 69  ? 98.047  -22.920 -14.244 1.00 59.69  ?  4321 PHE   C H      1 
ATOM   5589 H  HA     . PHE   B  2 69  ? 97.137  -22.759 -11.705 1.00 47.48  ?  4321 PHE   C HA     1 
ATOM   5590 H  HB2    . PHE   B  2 69  ? 99.060  -20.986 -12.822 1.00 42.94  ?  4321 PHE   C HB2    1 
ATOM   5591 H  HB3    . PHE   B  2 69  ? 98.343  -20.707 -11.432 1.00 42.94  ?  4321 PHE   C HB3    1 
ATOM   5592 H  HD1    . PHE   B  2 69  ? 100.701 -22.763 -12.979 1.00 49.57  ?  4321 PHE   C HD1    1 
ATOM   5593 H  HD2    . PHE   B  2 69  ? 99.188  -21.671 -9.456  1.00 46.18  ?  4321 PHE   C HD2    1 
ATOM   5594 H  HE1    . PHE   B  2 69  ? 102.365 -23.930 -11.895 1.00 48.31  ?  4321 PHE   C HE1    1 
ATOM   5595 H  HE2    . PHE   B  2 69  ? 100.850 -22.821 -8.387  1.00 49.92  ?  4321 PHE   C HE2    1 
ATOM   5596 H  HZ     . PHE   B  2 69  ? 102.468 -23.908 -9.601  1.00 49.49  ?  4321 PHE   C HZ     1 
ATOM   5597 N  N      . GLY   B  2 70  ? 95.576  -20.816 -12.118 1.00 41.93  ?  4322 GLY   C N      1 
ATOM   5598 C  CA     . GLY   B  2 70  ? 94.667  -19.742 -12.479 1.00 38.79  ?  4322 GLY   C CA     1 
ATOM   5599 C  C      . GLY   B  2 70  ? 95.458  -18.514 -12.890 1.00 39.22  ?  4322 GLY   C C      1 
ATOM   5600 O  O      . GLY   B  2 70  ? 96.403  -18.115 -12.199 1.00 41.42  ?  4322 GLY   C O      1 
ATOM   5601 H  H      . GLY   B  2 70  ? 95.517  -21.070 -11.298 1.00 50.84  ?  4322 GLY   C H      1 
ATOM   5602 H  HA2    . GLY   B  2 70  ? 94.106  -20.019 -13.220 1.00 47.08  ?  4322 GLY   C HA2    1 
ATOM   5603 H  HA3    . GLY   B  2 70  ? 94.103  -19.517 -11.723 1.00 47.08  ?  4322 GLY   C HA3    1 
ATOM   5604 N  N      . GLY   B  2 71  ? 95.072  -17.894 -14.013 1.00 39.46  ?  4323 GLY   C N      1 
ATOM   5605 C  CA     . GLY   B  2 71  ? 95.930  -16.881 -14.612 1.00 42.06  ?  4323 GLY   C CA     1 
ATOM   5606 C  C      . GLY   B  2 71  ? 96.123  -15.662 -13.731 1.00 39.86  ?  4323 GLY   C C      1 
ATOM   5607 O  O      . GLY   B  2 71  ? 97.253  -15.219 -13.496 1.00 39.49  ?  4323 GLY   C O      1 
ATOM   5608 H  H      . GLY   B  2 71  ? 94.337  -18.042 -14.433 1.00 47.87  ?  4323 GLY   C H      1 
ATOM   5609 H  HA2    . GLY   B  2 71  ? 96.802  -17.267 -14.789 1.00 50.99  ?  4323 GLY   C HA2    1 
ATOM   5610 H  HA3    . GLY   B  2 71  ? 95.538  -16.588 -15.450 1.00 50.99  ?  4323 GLY   C HA3    1 
ATOM   5611 N  N      . ALA   B  2 72  ? 95.021  -15.100 -13.231 1.00 39.92  ?  4324 ALA   C N      1 
ATOM   5612 C  CA     . ALA   B  2 72  ? 95.109  -13.881 -12.438 1.00 42.74  ?  4324 ALA   C CA     1 
ATOM   5613 C  C      . ALA   B  2 72  ? 96.116  -14.021 -11.300 1.00 43.04  ?  4324 ALA   C C      1 
ATOM   5614 O  O      . ALA   B  2 72  ? 96.866  -13.081 -11.008 1.00 44.59  ?  4324 ALA   C O      1 
ATOM   5615 C  CB     . ALA   B  2 72  ? 93.735  -13.504 -11.889 1.00 43.47  ?  4324 ALA   C CB     1 
ATOM   5616 H  H      . ALA   B  2 72  ? 94.222  -15.403 -13.336 1.00 48.43  ?  4324 ALA   C H      1 
ATOM   5617 H  HA     . ALA   B  2 72  ? 95.409  -13.163 -13.017 1.00 51.81  ?  4324 ALA   C HA     1 
ATOM   5618 H  HB1    . ALA   B  2 72  ? 93.795  -12.638 -11.457 1.00 52.69  ?  4324 ALA   C HB1    1 
ATOM   5619 H  HB2    . ALA   B  2 72  ? 93.101  -13.465 -12.622 1.00 52.69  ?  4324 ALA   C HB2    1 
ATOM   5620 H  HB3    . ALA   B  2 72  ? 93.457  -14.175 -11.246 1.00 52.69  ?  4324 ALA   C HB3    1 
ATOM   5621 N  N      . SER   B  2 73  ? 96.149  -15.178 -10.638 1.00 45.88  ?  4325 SER   C N      1 
ATOM   5622 C  CA     . SER   B  2 73  ? 97.042  -15.332 -9.503  1.00 40.48  ?  4325 SER   C CA     1 
ATOM   5623 C  C      . SER   B  2 73  ? 98.505  -15.425 -9.909  1.00 44.47  ?  4325 SER   C C      1 
ATOM   5624 O  O      . SER   B  2 73  ? 99.371  -15.370 -9.028  1.00 45.89  ?  4325 SER   C O      1 
ATOM   5625 C  CB     . SER   B  2 73  ? 96.658  -16.573 -8.691  1.00 39.28  ?  4325 SER   C CB     1 
ATOM   5626 O  OG     . SER   B  2 73  ? 96.927  -17.775 -9.402  1.00 44.30  ?  4325 SER   C OG     1 
ATOM   5627 H  H      . SER   B  2 73  ? 95.674  -15.869 -10.825 1.00 55.58  ?  4325 SER   C H      1 
ATOM   5628 H  HA     . SER   B  2 73  ? 96.941  -14.556 -8.930  1.00 49.09  ?  4325 SER   C HA     1 
ATOM   5629 H  HB2    . SER   B  2 73  ? 97.169  -16.577 -7.867  1.00 47.65  ?  4325 SER   C HB2    1 
ATOM   5630 H  HB3    . SER   B  2 73  ? 95.709  -16.534 -8.492  1.00 47.65  ?  4325 SER   C HB3    1 
ATOM   5631 H  HG     . SER   B  2 73  ? 96.518  -17.773 -10.136 1.00 53.69  ?  4325 SER   C HG     1 
ATOM   5632 N  N      . CYS   B  2 74  ? 98.805  -15.547 -11.199 1.00 46.96  ?  4326 CYS   C N      1 
ATOM   5633 C  CA     . CYS   B  2 74  ? 100.179 -15.621 -11.679 1.00 46.53  ?  4326 CYS   C CA     1 
ATOM   5634 C  C      . CYS   B  2 74  ? 100.596 -14.364 -12.429 1.00 47.82  ?  4326 CYS   C C      1 
ATOM   5635 O  O      . CYS   B  2 74  ? 101.686 -14.326 -13.014 1.00 47.86  ?  4326 CYS   C O      1 
ATOM   5636 C  CB     . CYS   B  2 74  ? 100.354 -16.846 -12.578 1.00 50.13  ?  4326 CYS   C CB     1 
ATOM   5637 S  SG     . CYS   B  2 74  ? 99.906  -18.402 -11.828 1.00 47.38  ?  4326 CYS   C SG     1 
ATOM   5638 H  H      . CYS   B  2 74  ? 98.218  -15.591 -11.825 1.00 56.87  ?  4326 CYS   C H      1 
ATOM   5639 H  HA     . CYS   B  2 74  ? 100.769 -15.722 -10.916 1.00 56.36  ?  4326 CYS   C HA     1 
ATOM   5640 H  HB2    . CYS   B  2 74  ? 99.799  -16.732 -13.365 1.00 60.68  ?  4326 CYS   C HB2    1 
ATOM   5641 H  HB3    . CYS   B  2 74  ? 101.287 -16.906 -12.837 1.00 60.68  ?  4326 CYS   C HB3    1 
ATOM   5642 H  HG     . CYS   B  2 74  ? 98.762  -18.348 -11.472 1.00 57.38  ?  4326 CYS   C HG     1 
ATOM   5643 N  N      . CYS   B  2 75  ? 99.751  -13.340 -12.426 1.00 44.61  ?  4327 CYS   C N      1 
ATOM   5644 C  CA     . CYS   B  2 75  ? 100.021 -12.087 -13.117 1.00 45.99  ?  4327 CYS   C CA     1 
ATOM   5645 C  C      . CYS   B  2 75  ? 100.567 -11.070 -12.124 1.00 42.86  ?  4327 CYS   C C      1 
ATOM   5646 O  O      . CYS   B  2 75  ? 99.891  -10.714 -11.154 1.00 47.69  ?  4327 CYS   C O      1 
ATOM   5647 C  CB     . CYS   B  2 75  ? 98.768  -11.544 -13.797 1.00 45.80  ?  4327 CYS   C CB     1 
ATOM   5648 S  SG     . CYS   B  2 75  ? 99.036  -9.879  -14.450 1.00 48.55  ?  4327 CYS   C SG     1 
ATOM   5649 H  H      . CYS   B  2 75  ? 98.993  -13.348 -12.020 1.00 54.05  ?  4327 CYS   C H      1 
ATOM   5650 H  HA     . CYS   B  2 75  ? 100.693 -12.245 -13.799 1.00 55.71  ?  4327 CYS   C HA     1 
ATOM   5651 H  HB2    . CYS   B  2 75  ? 98.525  -12.126 -14.534 1.00 55.49  ?  4327 CYS   C HB2    1 
ATOM   5652 H  HB3    . CYS   B  2 75  ? 98.045  -11.506 -13.151 1.00 55.49  ?  4327 CYS   C HB3    1 
ATOM   5653 N  N      . LEU   B  2 76  ? 101.774 -10.575 -12.400 1.00 46.67  ?  4328 LEU   C N      1 
ATOM   5654 C  CA     . LEU   B  2 76  ? 102.415 -9.603  -11.517 1.00 46.70  ?  4328 LEU   C CA     1 
ATOM   5655 C  C      . LEU   B  2 76  ? 101.562 -8.355  -11.326 1.00 43.57  ?  4328 LEU   C C      1 
ATOM   5656 O  O      . LEU   B  2 76  ? 101.450 -7.838  -10.211 1.00 45.95  ?  4328 LEU   C O      1 
ATOM   5657 C  CB     . LEU   B  2 76  ? 103.782 -9.221  -12.072 1.00 41.11  ?  4328 LEU   C CB     1 
ATOM   5658 C  CG     . LEU   B  2 76  ? 104.595 -8.210  -11.270 1.00 46.06  ?  4328 LEU   C CG     1 
ATOM   5659 C  CD1    . LEU   B  2 76  ? 105.095 -8.906  -10.013 1.00 44.73  ?  4328 LEU   C CD1    1 
ATOM   5660 C  CD2    . LEU   B  2 76  ? 105.722 -7.675  -12.098 1.00 54.36  ?  4328 LEU   C CD2    1 
ATOM   5661 H  H      . LEU   B  2 76  ? 102.243 -10.785 -13.089 1.00 56.52  ?  4328 LEU   C H      1 
ATOM   5662 H  HA     . LEU   B  2 76  ? 102.533 -10.016 -10.647 1.00 56.56  ?  4328 LEU   C HA     1 
ATOM   5663 H  HB2    . LEU   B  2 76  ? 104.315 -10.029 -12.133 1.00 49.85  ?  4328 LEU   C HB2    1 
ATOM   5664 H  HB3    . LEU   B  2 76  ? 103.651 -8.842  -12.955 1.00 49.85  ?  4328 LEU   C HB3    1 
ATOM   5665 H  HG     . LEU   B  2 76  ? 104.057 -7.445  -11.013 1.00 55.79  ?  4328 LEU   C HG     1 
ATOM   5666 H  HD11   . LEU   B  2 76  ? 105.670 -8.298  -9.523  1.00 54.20  ?  4328 LEU   C HD11   1 
ATOM   5667 H  HD12   . LEU   B  2 76  ? 104.333 -9.154  -9.465  1.00 54.20  ?  4328 LEU   C HD12   1 
ATOM   5668 H  HD13   . LEU   B  2 76  ? 105.592 -9.699  -10.267 1.00 54.20  ?  4328 LEU   C HD13   1 
ATOM   5669 H  HD21   . LEU   B  2 76  ? 106.233 -7.044  -11.568 1.00 65.75  ?  4328 LEU   C HD21   1 
ATOM   5670 H  HD22   . LEU   B  2 76  ? 106.290 -8.412  -12.373 1.00 65.75  ?  4328 LEU   C HD22   1 
ATOM   5671 H  HD23   . LEU   B  2 76  ? 105.357 -7.231  -12.879 1.00 65.75  ?  4328 LEU   C HD23   1 
ATOM   5672 N  N      . TYR   B  2 77  ? 100.988 -7.837  -12.403 1.00 45.34  ?  4329 TYR   C N      1 
ATOM   5673 C  CA     . TYR   B  2 77  ? 100.185 -6.629  -12.311 1.00 48.44  ?  4329 TYR   C CA     1 
ATOM   5674 C  C      . TYR   B  2 77  ? 98.906  -6.888  -11.525 1.00 50.79  ?  4329 TYR   C C      1 
ATOM   5675 O  O      . TYR   B  2 77  ? 98.580  -6.138  -10.593 1.00 51.59  ?  4329 TYR   C O      1 
ATOM   5676 C  CB     . TYR   B  2 77  ? 99.942  -6.118  -13.727 1.00 50.82  ?  4329 TYR   C CB     1 
ATOM   5677 C  CG     . TYR   B  2 77  ? 101.276 -6.048  -14.450 1.00 50.44  ?  4329 TYR   C CG     1 
ATOM   5678 C  CD1    . TYR   B  2 77  ? 102.269 -5.179  -14.017 1.00 52.37  ?  4329 TYR   C CD1    1 
ATOM   5679 C  CD2    . TYR   B  2 77  ? 101.564 -6.875  -15.524 1.00 54.19  ?  4329 TYR   C CD2    1 
ATOM   5680 C  CE1    . TYR   B  2 77  ? 103.489 -5.113  -14.639 1.00 64.45  ?  4329 TYR   C CE1    1 
ATOM   5681 C  CE2    . TYR   B  2 77  ? 102.802 -6.812  -16.164 1.00 59.02  ?  4329 TYR   C CE2    1 
ATOM   5682 C  CZ     . TYR   B  2 77  ? 103.757 -5.930  -15.707 1.00 56.61  ?  4329 TYR   C CZ     1 
ATOM   5683 O  OH     . TYR   B  2 77  ? 104.982 -5.855  -16.321 1.00 60.74  ?  4329 TYR   C OH     1 
ATOM   5684 H  H      . TYR   B  2 77  ? 101.048 -8.165  -13.196 1.00 54.93  ?  4329 TYR   C H      1 
ATOM   5685 H  HA     . TYR   B  2 77  ? 100.648 -5.928  -11.826 1.00 58.64  ?  4329 TYR   C HA     1 
ATOM   5686 H  HB2    . TYR   B  2 77  ? 99.354  -6.726  -14.203 1.00 61.50  ?  4329 TYR   C HB2    1 
ATOM   5687 H  HB3    . TYR   B  2 77  ? 99.549  -5.232  -13.698 1.00 61.50  ?  4329 TYR   C HB3    1 
ATOM   5688 H  HD1    . TYR   B  2 77  ? 102.101 -4.627  -13.288 1.00 63.37  ?  4329 TYR   C HD1    1 
ATOM   5689 H  HD2    . TYR   B  2 77  ? 100.923 -7.479  -15.823 1.00 65.55  ?  4329 TYR   C HD2    1 
ATOM   5690 H  HE1    . TYR   B  2 77  ? 104.135 -4.515  -14.337 1.00 77.86  ?  4329 TYR   C HE1    1 
ATOM   5691 H  HE2    . TYR   B  2 77  ? 102.981 -7.362  -16.892 1.00 71.34  ?  4329 TYR   C HE2    1 
ATOM   5692 H  HH     . TYR   B  2 77  ? 105.010 -6.387  -16.971 1.00 73.41  ?  4329 TYR   C HH     1 
ATOM   5693 N  N      . CYS   B  2 78  ? 98.216  -7.990  -11.820 1.00 50.35  ?  4330 CYS   C N      1 
ATOM   5694 C  CA     . CYS   B  2 78  ? 97.051  -8.366  -11.021 1.00 48.42  ?  4330 CYS   C CA     1 
ATOM   5695 C  C      . CYS   B  2 78  ? 97.400  -8.473  -9.543  1.00 44.18  ?  4330 CYS   C C      1 
ATOM   5696 O  O      . CYS   B  2 78  ? 96.701  -7.916  -8.688  1.00 50.90  ?  4330 CYS   C O      1 
ATOM   5697 C  CB     . CYS   B  2 78  ? 96.472  -9.694  -11.517 1.00 46.44  ?  4330 CYS   C CB     1 
ATOM   5698 S  SG     . CYS   B  2 78  ? 95.453  -9.615  -13.010 1.00 48.75  ?  4330 CYS   C SG     1 
ATOM   5699 H  H      . CYS   B  2 78  ? 98.398  -8.527  -12.466 1.00 60.94  ?  4330 CYS   C H      1 
ATOM   5700 H  HA     . CYS   B  2 78  ? 96.377  -7.677  -11.130 1.00 58.62  ?  4330 CYS   C HA     1 
ATOM   5701 H  HB2    . CYS   B  2 78  ? 97.210  -10.293 -11.706 1.00 56.25  ?  4330 CYS   C HB2    1 
ATOM   5702 H  HB3    . CYS   B  2 78  ? 95.917  -10.063 -10.812 1.00 56.25  ?  4330 CYS   C HB3    1 
ATOM   5703 N  N      . ARG   B  2 79  ? 98.482  -9.185  -9.222  1.00 44.49  ?  4331 ARG   C N      1 
ATOM   5704 C  CA     . ARG   B  2 79  ? 98.779  -9.497  -7.824  1.00 48.14  ?  4331 ARG   C CA     1 
ATOM   5705 C  C      . ARG   B  2 79  ? 99.283  -8.298  -7.036  1.00 47.18  ?  4331 ARG   C C      1 
ATOM   5706 O  O      . ARG   B  2 79  ? 99.261  -8.329  -5.801  1.00 49.35  ?  4331 ARG   C O      1 
ATOM   5707 C  CB     . ARG   B  2 79  ? 99.831  -10.604 -7.729  1.00 49.93  ?  4331 ARG   C CB     1 
ATOM   5708 C  CG     . ARG   B  2 79  ? 99.400  -11.981 -8.142  1.00 43.59  ?  4331 ARG   C CG     1 
ATOM   5709 C  CD     . ARG   B  2 79  ? 98.377  -12.544 -7.157  1.00 44.03  ?  4331 ARG   C CD     1 
ATOM   5710 N  NE     . ARG   B  2 79  ? 98.888  -12.629 -5.794  1.00 45.98  ?  4331 ARG   C NE     1 
ATOM   5711 C  CZ     . ARG   B  2 79  ? 99.458  -13.703 -5.265  1.00 42.63  ?  4331 ARG   C CZ     1 
ATOM   5712 N  NH1    . ARG   B  2 79  ? 99.706  -14.780 -5.989  1.00 41.40  ?  4331 ARG   C NH1    1 
ATOM   5713 N  NH2    . ARG   B  2 79  ? 99.795  -13.693 -3.978  1.00 46.43  ?  4331 ARG   C NH2    1 
ATOM   5714 H  H      . ARG   B  2 79  ? 99.053  -9.494  -9.787  1.00 53.91  ?  4331 ARG   C H      1 
ATOM   5715 H  HA     . ARG   B  2 79  ? 97.953  -9.808  -7.422  1.00 58.29  ?  4331 ARG   C HA     1 
ATOM   5716 H  HB2    . ARG   B  2 79  ? 100.578 -10.359 -8.297  1.00 60.44  ?  4331 ARG   C HB2    1 
ATOM   5717 H  HB3    . ARG   B  2 79  ? 100.122 -10.664 -6.805  1.00 60.44  ?  4331 ARG   C HB3    1 
ATOM   5718 H  HG2    . ARG   B  2 79  ? 98.992  -11.943 -9.022  1.00 52.83  ?  4331 ARG   C HG2    1 
ATOM   5719 H  HG3    . ARG   B  2 79  ? 100.169 -12.572 -8.159  1.00 52.83  ?  4331 ARG   C HG3    1 
ATOM   5720 H  HD2    . ARG   B  2 79  ? 97.597  -11.967 -7.148  1.00 53.36  ?  4331 ARG   C HD2    1 
ATOM   5721 H  HD3    . ARG   B  2 79  ? 98.126  -13.438 -7.439  1.00 53.36  ?  4331 ARG   C HD3    1 
ATOM   5722 H  HE     . ARG   B  2 79  ? 98.814  -11.932 -5.296  1.00 55.69  ?  4331 ARG   C HE     1 
ATOM   5723 H  HH11   . ARG   B  2 79  ? 99.496  -14.795 -6.823  1.00 50.20  ?  4331 ARG   C HH11   1 
ATOM   5724 H  HH12   . ARG   B  2 79  ? 100.076 -15.466 -5.626  1.00 50.20  ?  4331 ARG   C HH12   1 
ATOM   5725 H  HH21   . ARG   B  2 79  ? 99.642  -12.994 -3.500  1.00 56.24  ?  4331 ARG   C HH21   1 
ATOM   5726 H  HH22   . ARG   B  2 79  ? 100.165 -14.384 -3.625  1.00 56.24  ?  4331 ARG   C HH22   1 
ATOM   5727 N  N      . CYS   B  2 80  ? 99.765  -7.261  -7.716  1.00 54.78  ?  4332 CYS   C N      1 
ATOM   5728 C  CA     . CYS   B  2 80  ? 100.354 -6.100  -7.065  1.00 48.76  ?  4332 CYS   C CA     1 
ATOM   5729 C  C      . CYS   B  2 80  ? 99.447  -4.883  -7.145  1.00 47.19  ?  4332 CYS   C C      1 
ATOM   5730 O  O      . CYS   B  2 80  ? 99.829  -3.808  -6.681  1.00 55.87  ?  4332 CYS   C O      1 
ATOM   5731 C  CB     . CYS   B  2 80  ? 101.714 -5.784  -7.687  1.00 47.75  ?  4332 CYS   C CB     1 
ATOM   5732 S  SG     . CYS   B  2 80  ? 103.008 -6.966  -7.227  1.00 59.30  ?  4332 CYS   C SG     1 
ATOM   5733 H  H      . CYS   B  2 80  ? 99.761  -7.207  -8.575  1.00 66.25  ?  4332 CYS   C H      1 
ATOM   5734 H  HA     . CYS   B  2 80  ? 100.507 -6.299  -6.128  1.00 59.04  ?  4332 CYS   C HA     1 
ATOM   5735 H  HB2    . CYS   B  2 80  ? 101.627 -5.800  -8.653  1.00 57.82  ?  4332 CYS   C HB2    1 
ATOM   5736 H  HB3    . CYS   B  2 80  ? 101.996 -4.904  -7.394  1.00 57.82  ?  4332 CYS   C HB3    1 
ATOM   5737 H  HG     . CYS   B  2 80  ? 104.032 -6.655  -7.770  1.00 71.68  ?  4332 CYS   C HG     1 
ATOM   5738 N  N      . HIS   B  2 81  ? 98.247  -5.040  -7.700  1.00 48.99  ?  4333 HIS   C N      1 
ATOM   5739 C  CA     . HIS   B  2 81  ? 97.277  -3.955  -7.812  1.00 52.83  ?  4333 HIS   C CA     1 
ATOM   5740 C  C      . HIS   B  2 81  ? 97.855  -2.767  -8.572  1.00 50.06  ?  4333 HIS   C C      1 
ATOM   5741 O  O      . HIS   B  2 81  ? 97.659  -1.608  -8.195  1.00 69.18  ?  4333 HIS   C O      1 
ATOM   5742 C  CB     . HIS   B  2 81  ? 96.772  -3.513  -6.439  1.00 50.14  ?  4333 HIS   C CB     1 
ATOM   5743 C  CG     . HIS   B  2 81  ? 96.337  -4.643  -5.562  1.00 55.57  ?  4333 HIS   C CG     1 
ATOM   5744 N  ND1    . HIS   B  2 81  ? 96.223  -4.522  -4.194  1.00 63.81  ?  4333 HIS   C ND1    1 
ATOM   5745 C  CD2    . HIS   B  2 81  ? 96.014  -5.926  -5.855  1.00 61.09  ?  4333 HIS   C CD2    1 
ATOM   5746 C  CE1    . HIS   B  2 81  ? 95.831  -5.676  -3.683  1.00 62.70  ?  4333 HIS   C CE1    1 
ATOM   5747 N  NE2    . HIS   B  2 81  ? 95.698  -6.545  -4.668  1.00 56.64  ?  4333 HIS   C NE2    1 
ATOM   5748 H  H      . HIS   B  2 81  ? 97.965  -5.784  -8.027  1.00 59.31  ?  4333 HIS   C H      1 
ATOM   5749 H  HA     . HIS   B  2 81  ? 96.519  -4.287  -8.318  1.00 63.92  ?  4333 HIS   C HA     1 
ATOM   5750 H  HB2    . HIS   B  2 81  ? 97.485  -3.042  -5.981  1.00 60.70  ?  4333 HIS   C HB2    1 
ATOM   5751 H  HB3    . HIS   B  2 81  ? 96.010  -2.925  -6.561  1.00 60.70  ?  4333 HIS   C HB3    1 
ATOM   5752 H  HD2    . HIS   B  2 81  ? 96.007  -6.315  -6.699  1.00 73.83  ?  4333 HIS   C HD2    1 
ATOM   5753 H  HE1    . HIS   B  2 81  ? 95.675  -5.847  -2.782  1.00 75.77  ?  4333 HIS   C HE1    1 
ATOM   5754 H  HE2    . HIS   B  2 81  ? 95.454  -7.366  -4.582  1.00 68.49  ?  4333 HIS   C HE2    1 
ATOM   5755 N  N      . ILE   B  2 82  ? 98.560  -3.047  -9.657  1.00 51.90  ?  4334 ILE   C N      1 
ATOM   5756 C  CA     . ILE   B  2 82  ? 99.103  -1.992  -10.492 1.00 53.37  ?  4334 ILE   C CA     1 
ATOM   5757 C  C      . ILE   B  2 82  ? 98.563  -2.157  -11.903 1.00 56.26  ?  4334 ILE   C C      1 
ATOM   5758 O  O      . ILE   B  2 82  ? 98.052  -3.212  -12.286 1.00 57.66  ?  4334 ILE   C O      1 
ATOM   5759 C  CB     . ILE   B  2 82  ? 100.637 -1.990  -10.507 1.00 53.42  ?  4334 ILE   C CB     1 
ATOM   5760 C  CG1    . ILE   B  2 82  ? 101.173 -3.247  -11.185 1.00 57.49  ?  4334 ILE   C CG1    1 
ATOM   5761 C  CG2    . ILE   B  2 82  ? 101.188 -1.935  -9.090  1.00 55.17  ?  4334 ILE   C CG2    1 
ATOM   5762 C  CD1    . ILE   B  2 82  ? 102.659 -3.435  -10.975 1.00 54.54  ?  4334 ILE   C CD1    1 
ATOM   5763 H  H      . ILE   B  2 82  ? 98.738  -3.843  -9.931  1.00 62.81  ?  4334 ILE   C H      1 
ATOM   5764 H  HA     . ILE   B  2 82  ? 98.801  -1.137  -10.148 1.00 64.56  ?  4334 ILE   C HA     1 
ATOM   5765 H  HB     . ILE   B  2 82  ? 100.919 -1.205  -11.002 1.00 64.63  ?  4334 ILE   C HB     1 
ATOM   5766 H  HG12   . ILE   B  2 82  ? 100.718 -4.021  -10.821 1.00 69.51  ?  4334 ILE   C HG12   1 
ATOM   5767 H  HG13   . ILE   B  2 82  ? 101.011 -3.184  -12.139 1.00 69.51  ?  4334 ILE   C HG13   1 
ATOM   5768 H  HG21   . ILE   B  2 82  ? 102.095 -1.592  -9.118  1.00 66.73  ?  4334 ILE   C HG21   1 
ATOM   5769 H  HG22   . ILE   B  2 82  ? 100.628 -1.349  -8.557  1.00 66.73  ?  4334 ILE   C HG22   1 
ATOM   5770 H  HG23   . ILE   B  2 82  ? 101.183 -2.829  -8.715  1.00 66.73  ?  4334 ILE   C HG23   1 
ATOM   5771 H  HD11   . ILE   B  2 82  ? 103.007 -4.007  -11.676 1.00 65.97  ?  4334 ILE   C HD11   1 
ATOM   5772 H  HD12   . ILE   B  2 82  ? 103.095 -2.569  -11.008 1.00 65.97  ?  4334 ILE   C HD12   1 
ATOM   5773 H  HD13   . ILE   B  2 82  ? 102.806 -3.846  -10.109 1.00 65.97  ?  4334 ILE   C HD13   1 
ATOM   5774 N  N      . ASP   B  2 83  ? 98.678  -1.080  -12.670 1.00 57.49  ?  4335 ASP   C N      1 
ATOM   5775 C  CA     . ASP   B  2 83  ? 98.087  -1.036  -13.989 1.00 60.30  ?  4335 ASP   C CA     1 
ATOM   5776 C  C      . ASP   B  2 83  ? 98.806  -2.006  -14.919 1.00 54.09  ?  4335 ASP   C C      1 
ATOM   5777 O  O      . ASP   B  2 83  ? 99.994  -2.297  -14.759 1.00 54.42  ?  4335 ASP   C O      1 
ATOM   5778 C  CB     . ASP   B  2 83  ? 98.168  0.386   -14.545 1.00 56.18  ?  4335 ASP   C CB     1 
ATOM   5779 C  CG     . ASP   B  2 83  ? 97.174  1.333   -13.885 1.00 68.27  ?  4335 ASP   C CG     1 
ATOM   5780 O  OD1    . ASP   B  2 83  ? 96.341  0.889   -13.064 1.00 65.97  ?  4335 ASP   C OD1    1 
ATOM   5781 O  OD2    . ASP   B  2 83  ? 97.222  2.541   -14.186 1.00 73.90  ?  4335 ASP   C OD2    1 
ATOM   5782 H  H      . ASP   B  2 83  ? 99.095  -0.362  -12.445 1.00 69.51  ?  4335 ASP   C H      1 
ATOM   5783 H  HA     . ASP   B  2 83  ? 97.153  -1.293  -13.947 1.00 72.89  ?  4335 ASP   C HA     1 
ATOM   5784 H  HB2    . ASP   B  2 83  ? 99.061  0.735   -14.393 1.00 67.94  ?  4335 ASP   C HB2    1 
ATOM   5785 H  HB3    . ASP   B  2 83  ? 97.977  0.366   -15.496 1.00 67.94  ?  4335 ASP   C HB3    1 
ATOM   5786 N  N      . HIS   B  2 84  ? 98.074  -2.529  -15.874 1.00 62.10  ?  4336 HIS   C N      1 
ATOM   5787 C  CA     . HIS   B  2 84  ? 98.730  -3.447  -16.788 1.00 65.28  ?  4336 HIS   C CA     1 
ATOM   5788 C  C      . HIS   B  2 84  ? 99.465  -2.671  -17.880 1.00 61.12  ?  4336 HIS   C C      1 
ATOM   5789 O  O      . HIS   B  2 84  ? 99.015  -1.602  -18.296 1.00 67.28  ?  4336 HIS   C O      1 
ATOM   5790 C  CB     . HIS   B  2 84  ? 97.718  -4.392  -17.416 1.00 65.38  ?  4336 HIS   C CB     1 
ATOM   5791 C  CG     . HIS   B  2 84  ? 97.266  -5.486  -16.496 1.00 61.80  ?  4336 HIS   C CG     1 
ATOM   5792 N  ND1    . HIS   B  2 84  ? 96.440  -5.261  -15.416 1.00 53.22  ?  4336 HIS   C ND1    1 
ATOM   5793 C  CD2    . HIS   B  2 84  ? 97.535  -6.811  -16.497 1.00 55.50  ?  4336 HIS   C CD2    1 
ATOM   5794 C  CE1    . HIS   B  2 84  ? 96.211  -6.405  -14.801 1.00 51.78  ?  4336 HIS   C CE1    1 
ATOM   5795 N  NE2    . HIS   B  2 84  ? 96.867  -7.359  -15.434 1.00 53.00  ?  4336 HIS   C NE2    1 
ATOM   5796 H  H      . HIS   B  2 84  ? 97.238  -2.381  -16.012 1.00 75.05  ?  4336 HIS   C H      1 
ATOM   5797 H  HA     . HIS   B  2 84  ? 99.380  -3.979  -16.303 1.00 78.85  ?  4336 HIS   C HA     1 
ATOM   5798 H  HB2    . HIS   B  2 84  ? 96.935  -3.882  -17.677 1.00 78.98  ?  4336 HIS   C HB2    1 
ATOM   5799 H  HB3    . HIS   B  2 84  ? 98.119  -4.806  -18.196 1.00 78.98  ?  4336 HIS   C HB3    1 
ATOM   5800 H  HD1    . HIS   B  2 84  ? 96.123  -4.497  -15.180 1.00 64.38  ?  4336 HIS   C HD1    1 
ATOM   5801 H  HD2    . HIS   B  2 84  ? 98.072  -7.266  -17.106 1.00 67.12  ?  4336 HIS   C HD2    1 
ATOM   5802 H  HE1    . HIS   B  2 84  ? 95.677  -6.520  -14.048 1.00 62.66  ?  4336 HIS   C HE1    1 
ATOM   5803 N  N      . PRO   B  2 85  ? 100.616 -3.169  -18.341 1.00 68.46  ?  4337 PRO   C N      1 
ATOM   5804 C  CA     . PRO   B  2 85  ? 101.371 -2.426  -19.370 1.00 76.32  ?  4337 PRO   C CA     1 
ATOM   5805 C  C      . PRO   B  2 85  ? 100.719 -2.419  -20.746 1.00 81.36  ?  4337 PRO   C C      1 
ATOM   5806 O  O      . PRO   B  2 85  ? 101.155 -1.637  -21.597 1.00 82.24  ?  4337 PRO   C O      1 
ATOM   5807 C  CB     . PRO   B  2 85  ? 102.725 -3.143  -19.394 1.00 69.73  ?  4337 PRO   C CB     1 
ATOM   5808 C  CG     . PRO   B  2 85  ? 102.376 -4.557  -19.014 1.00 72.41  ?  4337 PRO   C CG     1 
ATOM   5809 C  CD     . PRO   B  2 85  ? 101.275 -4.441  -17.983 1.00 74.78  ?  4337 PRO   C CD     1 
ATOM   5810 H  HA     . PRO   B  2 85  ? 101.496 -1.508  -19.083 1.00 92.11  ?  4337 PRO   C HA     1 
ATOM   5811 H  HB2    . PRO   B  2 85  ? 103.113 -3.101  -20.282 1.00 84.20  ?  4337 PRO   C HB2    1 
ATOM   5812 H  HB3    . PRO   B  2 85  ? 103.330 -2.743  -18.749 1.00 84.20  ?  4337 PRO   C HB3    1 
ATOM   5813 H  HG2    . PRO   B  2 85  ? 102.066 -5.040  -19.796 1.00 87.41  ?  4337 PRO   C HG2    1 
ATOM   5814 H  HG3    . PRO   B  2 85  ? 103.154 -4.998  -18.638 1.00 87.41  ?  4337 PRO   C HG3    1 
ATOM   5815 H  HD2    . PRO   B  2 85  ? 100.655 -5.184  -18.053 1.00 90.26  ?  4337 PRO   C HD2    1 
ATOM   5816 H  HD3    . PRO   B  2 85  ? 101.643 -4.399  -17.087 1.00 90.26  ?  4337 PRO   C HD3    1 
ATOM   5817 N  N      . ASN   B  2 86  ? 99.722  -3.265  -21.004 1.00 89.77  ?  4338 ASN   C N      1 
ATOM   5818 C  CA     . ASN   B  2 86  ? 98.902  -3.069  -22.187 1.00 86.06  ?  4338 ASN   C CA     1 
ATOM   5819 C  C      . ASN   B  2 86  ? 98.431  -1.616  -22.182 1.00 98.26  ?  4338 ASN   C C      1 
ATOM   5820 O  O      . ASN   B  2 86  ? 98.188  -1.052  -21.104 1.00 94.15  ?  4338 ASN   C O      1 
ATOM   5821 C  CB     . ASN   B  2 86  ? 97.721  -4.048  -22.178 1.00 90.16  ?  4338 ASN   C CB     1 
ATOM   5822 C  CG     . ASN   B  2 86  ? 96.773  -3.852  -23.340 1.00 106.64 ?  4338 ASN   C CG     1 
ATOM   5823 O  OD1    . ASN   B  2 86  ? 96.395  -2.743  -23.680 1.00 101.86 ?  4338 ASN   C OD1    1 
ATOM   5824 N  ND2    . ASN   B  2 86  ? 96.396  -4.951  -23.968 1.00 101.64 ?  4338 ASN   C ND2    1 
ATOM   5825 H  H      . ASN   B  2 86  ? 99.508  -3.942  -20.519 1.00 108.24 ?  4338 ASN   C H      1 
ATOM   5826 H  HA     . ASN   B  2 86  ? 99.397  -3.241  -23.003 1.00 103.79 ?  4338 ASN   C HA     1 
ATOM   5827 H  HB2    . ASN   B  2 86  ? 98.063  -4.955  -22.223 1.00 108.72 ?  4338 ASN   C HB2    1 
ATOM   5828 H  HB3    . ASN   B  2 86  ? 97.216  -3.924  -21.359 1.00 108.72 ?  4338 ASN   C HB3    1 
ATOM   5829 H  HD21   . ASN   B  2 86  ? 95.857  -4.901  -24.637 1.00 122.50 ?  4338 ASN   C HD21   1 
ATOM   5830 H  HD22   . ASN   B  2 86  ? 96.688  -5.717  -23.708 1.00 122.50 ?  4338 ASN   C HD22   1 
ATOM   5831 N  N      . PRO   B  2 87  ? 98.408  -0.936  -23.329 1.00 111.01 ?  4339 PRO   C N      1 
ATOM   5832 C  CA     . PRO   B  2 87  ? 97.844  0.423   -23.327 1.00 103.04 ?  4339 PRO   C CA     1 
ATOM   5833 C  C      . PRO   B  2 87  ? 96.418  0.473   -22.801 1.00 103.93 ?  4339 PRO   C C      1 
ATOM   5834 O  O      . PRO   B  2 87  ? 96.057  1.412   -22.082 1.00 106.56 ?  4339 PRO   C O      1 
ATOM   5835 C  CB     . PRO   B  2 87  ? 97.924  0.833   -24.802 1.00 103.31 ?  4339 PRO   C CB     1 
ATOM   5836 C  CG     . PRO   B  2 87  ? 99.017  0.001   -25.391 1.00 116.73 ?  4339 PRO   C CG     1 
ATOM   5837 C  CD     . PRO   B  2 87  ? 99.326  -1.143  -24.466 1.00 114.26 ?  4339 PRO   C CD     1 
ATOM   5838 H  HA     . PRO   B  2 87  ? 98.403  1.015   -22.799 1.00 124.18 ?  4339 PRO   C HA     1 
ATOM   5839 H  HB2    . PRO   B  2 87  ? 97.077  0.650   -25.239 1.00 124.50 ?  4339 PRO   C HB2    1 
ATOM   5840 H  HB3    . PRO   B  2 87  ? 98.135  1.777   -24.869 1.00 124.50 ?  4339 PRO   C HB3    1 
ATOM   5841 H  HG2    . PRO   B  2 87  ? 98.722  -0.339  -26.251 1.00 140.60 ?  4339 PRO   C HG2    1 
ATOM   5842 H  HG3    . PRO   B  2 87  ? 99.804  0.555   -25.507 1.00 140.60 ?  4339 PRO   C HG3    1 
ATOM   5843 H  HD2    . PRO   B  2 87  ? 99.150  -1.992  -24.900 1.00 137.63 ?  4339 PRO   C HD2    1 
ATOM   5844 H  HD3    . PRO   B  2 87  ? 100.250 -1.106  -24.173 1.00 137.63 ?  4339 PRO   C HD3    1 
ATOM   5845 N  N      . LYS   B  2 88  ? 95.595  -0.518  -23.139 1.00 101.90 ?  4340 LYS   C N      1 
ATOM   5846 C  CA     . LYS   B  2 88  ? 94.207  -0.575  -22.707 1.00 97.66  ?  4340 LYS   C CA     1 
ATOM   5847 C  C      . LYS   B  2 88  ? 94.056  -1.246  -21.348 1.00 91.20  ?  4340 LYS   C C      1 
ATOM   5848 O  O      . LYS   B  2 88  ? 92.927  -1.419  -20.881 1.00 73.47  ?  4340 LYS   C O      1 
ATOM   5849 C  CB     . LYS   B  2 88  ? 93.370  -1.318  -23.757 1.00 94.26  ?  4340 LYS   C CB     1 
ATOM   5850 C  CG     . LYS   B  2 88  ? 92.470  -0.403  -24.600 1.00 111.00 ?  4340 LYS   C CG     1 
ATOM   5851 C  CD     . LYS   B  2 88  ? 92.227  -0.925  -26.011 1.00 113.52 ?  4340 LYS   C CD     1 
ATOM   5852 C  CE     . LYS   B  2 88  ? 90.908  -0.423  -26.602 1.00 110.44 ?  4340 LYS   C CE     1 
ATOM   5853 N  NZ     . LYS   B  2 88  ? 89.701  -1.081  -26.058 1.00 96.51  ?  4340 LYS   C NZ     1 
ATOM   5854 H  H      . LYS   B  2 88  ? 95.826  -1.184  -23.632 1.00 122.80 ?  4340 LYS   C H      1 
ATOM   5855 H  HA     . LYS   B  2 88  ? 93.853  0.326   -22.634 1.00 117.72 ?  4340 LYS   C HA     1 
ATOM   5856 H  HB2    . LYS   B  2 88  ? 93.970  -1.781  -24.362 1.00 113.63 ?  4340 LYS   C HB2    1 
ATOM   5857 H  HB3    . LYS   B  2 88  ? 92.798  -1.957  -23.303 1.00 113.63 ?  4340 LYS   C HB3    1 
ATOM   5858 H  HG2    . LYS   B  2 88  ? 91.609  -0.320  -24.161 1.00 133.72 ?  4340 LYS   C HG2    1 
ATOM   5859 H  HG3    . LYS   B  2 88  ? 92.890  0.468   -24.674 1.00 133.72 ?  4340 LYS   C HG3    1 
ATOM   5860 H  HD2    . LYS   B  2 88  ? 92.947  -0.627  -26.589 1.00 136.74 ?  4340 LYS   C HD2    1 
ATOM   5861 H  HD3    . LYS   B  2 88  ? 92.197  -1.894  -25.991 1.00 136.74 ?  4340 LYS   C HD3    1 
ATOM   5862 H  HE2    . LYS   B  2 88  ? 90.830  0.527   -26.420 1.00 133.05 ?  4340 LYS   C HE2    1 
ATOM   5863 H  HE3    . LYS   B  2 88  ? 90.919  -0.577  -27.559 1.00 133.05 ?  4340 LYS   C HE3    1 
ATOM   5864 H  HZ1    . LYS   B  2 88  ? 88.972  -0.746  -26.443 1.00 116.34 ?  4340 LYS   C HZ1    1 
ATOM   5865 H  HZ2    . LYS   B  2 88  ? 89.734  -1.956  -26.215 1.00 116.34 ?  4340 LYS   C HZ2    1 
ATOM   5866 H  HZ3    . LYS   B  2 88  ? 89.650  -0.946  -25.179 1.00 116.34 ?  4340 LYS   C HZ3    1 
ATOM   5867 N  N      . GLY   B  2 89  ? 95.164  -1.617  -20.707 1.00 87.00  ?  4341 GLY   C N      1 
ATOM   5868 C  CA     . GLY   B  2 89  ? 95.129  -2.239  -19.399 1.00 83.81  ?  4341 GLY   C CA     1 
ATOM   5869 C  C      . GLY   B  2 89  ? 94.688  -3.687  -19.375 1.00 78.72  ?  4341 GLY   C C      1 
ATOM   5870 O  O      . GLY   B  2 89  ? 94.616  -4.270  -18.289 1.00 83.16  ?  4341 GLY   C O      1 
ATOM   5871 H  H      . GLY   B  2 89  ? 95.959  -1.514  -21.019 1.00 104.92 ?  4341 GLY   C H      1 
ATOM   5872 H  HA2    . GLY   B  2 89  ? 96.019  -2.198  -19.015 1.00 101.09 ?  4341 GLY   C HA2    1 
ATOM   5873 H  HA3    . GLY   B  2 89  ? 94.519  -1.738  -18.836 1.00 101.09 ?  4341 GLY   C HA3    1 
ATOM   5874 N  N      . PHE   B  2 90  ? 94.400  -4.286  -20.531 1.00 84.85  ?  4342 PHE   C N      1 
ATOM   5875 C  CA     . PHE   B  2 90  ? 93.898  -5.654  -20.586 1.00 84.01  ?  4342 PHE   C CA     1 
ATOM   5876 C  C      . PHE   B  2 90  ? 94.949  -6.615  -20.048 1.00 78.48  ?  4342 PHE   C C      1 
ATOM   5877 O  O      . PHE   B  2 90  ? 96.153  -6.342  -20.092 1.00 72.65  ?  4342 PHE   C O      1 
ATOM   5878 C  CB     . PHE   B  2 90  ? 93.496  -5.979  -22.040 1.00 75.05  ?  4342 PHE   C CB     1 
ATOM   5879 C  CG     . PHE   B  2 90  ? 93.557  -7.441  -22.423 1.00 88.65  ?  4342 PHE   C CG     1 
ATOM   5880 C  CD1    . PHE   B  2 90  ? 94.747  -8.053  -22.771 1.00 89.17  ?  4342 PHE   C CD1    1 
ATOM   5881 C  CD2    . PHE   B  2 90  ? 92.402  -8.193  -22.465 1.00 90.60  ?  4342 PHE   C CD2    1 
ATOM   5882 C  CE1    . PHE   B  2 90  ? 94.780  -9.383  -23.130 1.00 85.60  ?  4342 PHE   C CE1    1 
ATOM   5883 C  CE2    . PHE   B  2 90  ? 92.437  -9.530  -22.818 1.00 78.22  ?  4342 PHE   C CE2    1 
ATOM   5884 C  CZ     . PHE   B  2 90  ? 93.628  -10.120 -23.153 1.00 84.83  ?  4342 PHE   C CZ     1 
ATOM   5885 H  H      . PHE   B  2 90  ? 94.487  -3.918  -21.303 1.00 102.35 ?  4342 PHE   C H      1 
ATOM   5886 H  HA     . PHE   B  2 90  ? 93.109  -5.767  -20.034 1.00 101.34 ?  4342 PHE   C HA     1 
ATOM   5887 H  HB2    . PHE   B  2 90  ? 92.583  -5.683  -22.177 1.00 90.58  ?  4342 PHE   C HB2    1 
ATOM   5888 H  HB3    . PHE   B  2 90  ? 94.093  -5.500  -22.636 1.00 90.58  ?  4342 PHE   C HB3    1 
ATOM   5889 H  HD1    . PHE   B  2 90  ? 95.536  -7.561  -22.762 1.00 107.53 ?  4342 PHE   C HD1    1 
ATOM   5890 H  HD2    . PHE   B  2 90  ? 91.589  -7.796  -22.252 1.00 109.25 ?  4342 PHE   C HD2    1 
ATOM   5891 H  HE1    . PHE   B  2 90  ? 95.588  -9.781  -23.359 1.00 103.24 ?  4342 PHE   C HE1    1 
ATOM   5892 H  HE2    . PHE   B  2 90  ? 91.653  -10.029 -22.828 1.00 94.39  ?  4342 PHE   C HE2    1 
ATOM   5893 H  HZ     . PHE   B  2 90  ? 93.653  -11.017 -23.394 1.00 102.32 ?  4342 PHE   C HZ     1 
ATOM   5894 N  N      . CYS   B  2 91  ? 94.489  -7.740  -19.503 1.00 66.36  ?  4343 CYS   C N      1 
ATOM   5895 C  CA     . CYS   B  2 91  ? 95.384  -8.722  -18.905 1.00 58.04  ?  4343 CYS   C CA     1 
ATOM   5896 C  C      . CYS   B  2 91  ? 95.403  -10.003 -19.715 1.00 53.60  ?  4343 CYS   C C      1 
ATOM   5897 O  O      . CYS   B  2 91  ? 94.352  -10.595 -19.986 1.00 57.94  ?  4343 CYS   C O      1 
ATOM   5898 C  CB     . CYS   B  2 91  ? 95.001  -9.056  -17.466 1.00 52.44  ?  4343 CYS   C CB     1 
ATOM   5899 S  SG     . CYS   B  2 91  ? 96.116  -10.275 -16.738 1.00 50.90  ?  4343 CYS   C SG     1 
ATOM   5900 H  H      . CYS   B  2 91  ? 93.657  -7.955  -19.469 1.00 80.16  ?  4343 CYS   C H      1 
ATOM   5901 H  HA     . CYS   B  2 91  ? 96.273  -8.335  -18.912 1.00 70.16  ?  4343 CYS   C HA     1 
ATOM   5902 H  HB2    . CYS   B  2 91  ? 95.041  -8.249  -16.929 1.00 63.45  ?  4343 CYS   C HB2    1 
ATOM   5903 H  HB3    . CYS   B  2 91  ? 94.102  -9.420  -17.451 1.00 63.45  ?  4343 CYS   C HB3    1 
ATOM   5904 N  N      . ASP   B  2 92  ? 96.616  -10.443 -20.055 1.00 63.63  ?  4344 ASP   C N      1 
ATOM   5905 C  CA     . ASP   B  2 92  ? 96.802  -11.689 -20.798 1.00 68.24  ?  4344 ASP   C CA     1 
ATOM   5906 C  C      . ASP   B  2 92  ? 96.254  -12.892 -20.053 1.00 61.57  ?  4344 ASP   C C      1 
ATOM   5907 O  O      . ASP   B  2 92  ? 95.775  -13.849 -20.670 1.00 55.42  ?  4344 ASP   C O      1 
ATOM   5908 C  CB     . ASP   B  2 92  ? 98.295  -11.935 -21.040 1.00 72.35  ?  4344 ASP   C CB     1 
ATOM   5909 C  CG     . ASP   B  2 92  ? 98.790  -11.413 -22.349 1.00 82.46  ?  4344 ASP   C CG     1 
ATOM   5910 O  OD1    . ASP   B  2 92  ? 97.996  -10.879 -23.140 1.00 92.54  ?  4344 ASP   C OD1    1 
ATOM   5911 O  OD2    . ASP   B  2 92  ? 100.001 -11.579 -22.598 1.00 83.59  ?  4344 ASP   C OD2    1 
ATOM   5912 H  H      . ASP   B  2 92  ? 97.350  -10.037 -19.868 1.00 76.88  ?  4344 ASP   C H      1 
ATOM   5913 H  HA     . ASP   B  2 92  ? 96.331  -11.592 -21.641 1.00 82.41  ?  4344 ASP   C HA     1 
ATOM   5914 H  HB2    . ASP   B  2 92  ? 98.801  -11.497 -20.338 1.00 87.34  ?  4344 ASP   C HB2    1 
ATOM   5915 H  HB3    . ASP   B  2 92  ? 98.461  -12.891 -21.022 1.00 87.34  ?  4344 ASP   C HB3    1 
ATOM   5916 N  N      . LEU   B  2 93  ? 96.424  -12.910 -18.738 1.00 52.84  ?  4345 LEU   C N      1 
ATOM   5917 C  CA     . LEU   B  2 93  ? 96.279  -14.127 -17.960 1.00 45.10  ?  4345 LEU   C CA     1 
ATOM   5918 C  C      . LEU   B  2 93  ? 94.948  -14.217 -17.238 1.00 43.86  ?  4345 LEU   C C      1 
ATOM   5919 O  O      . LEU   B  2 93  ? 94.447  -15.324 -17.012 1.00 46.70  ?  4345 LEU   C O      1 
ATOM   5920 C  CB     . LEU   B  2 93  ? 97.404  -14.205 -16.926 1.00 47.37  ?  4345 LEU   C CB     1 
ATOM   5921 C  CG     . LEU   B  2 93  ? 98.816  -14.378 -17.483 1.00 44.89  ?  4345 LEU   C CG     1 
ATOM   5922 C  CD1    . LEU   B  2 93  ? 99.879  -13.960 -16.483 1.00 52.28  ?  4345 LEU   C CD1    1 
ATOM   5923 C  CD2    . LEU   B  2 93  ? 99.049  -15.832 -17.919 1.00 50.58  ?  4345 LEU   C CD2    1 
ATOM   5924 H  H      . LEU   B  2 93  ? 96.626  -12.219 -18.268 1.00 63.93  ?  4345 LEU   C H      1 
ATOM   5925 H  HA     . LEU   B  2 93  ? 96.347  -14.893 -18.552 1.00 54.65  ?  4345 LEU   C HA     1 
ATOM   5926 H  HB2    . LEU   B  2 93  ? 97.398  -13.383 -16.410 1.00 57.36  ?  4345 LEU   C HB2    1 
ATOM   5927 H  HB3    . LEU   B  2 93  ? 97.230  -14.962 -16.346 1.00 57.36  ?  4345 LEU   C HB3    1 
ATOM   5928 H  HG     . LEU   B  2 93  ? 98.902  -13.799 -18.257 1.00 54.39  ?  4345 LEU   C HG     1 
ATOM   5929 H  HD11   . LEU   B  2 93  ? 100.755 -14.114 -16.870 1.00 63.26  ?  4345 LEU   C HD11   1 
ATOM   5930 H  HD12   . LEU   B  2 93  ? 99.768  -13.019 -16.279 1.00 63.26  ?  4345 LEU   C HD12   1 
ATOM   5931 H  HD13   . LEU   B  2 93  ? 99.777  -14.488 -15.675 1.00 63.26  ?  4345 LEU   C HD13   1 
ATOM   5932 H  HD21   . LEU   B  2 93  ? 99.938  -15.910 -18.299 1.00 61.21  ?  4345 LEU   C HD21   1 
ATOM   5933 H  HD22   . LEU   B  2 93  ? 98.968  -16.411 -17.145 1.00 61.21  ?  4345 LEU   C HD22   1 
ATOM   5934 H  HD23   . LEU   B  2 93  ? 98.384  -16.073 -18.583 1.00 61.21  ?  4345 LEU   C HD23   1 
ATOM   5935 N  N      . LYS   B  2 94  ? 94.364  -13.085 -16.876 1.00 45.40  ?  4346 LYS   C N      1 
ATOM   5936 C  CA     . LYS   B  2 94  ? 93.175  -13.096 -16.040 1.00 43.77  ?  4346 LYS   C CA     1 
ATOM   5937 C  C      . LYS   B  2 94  ? 92.026  -13.772 -16.777 1.00 41.93  ?  4346 LYS   C C      1 
ATOM   5938 O  O      . LYS   B  2 94  ? 91.798  -13.544 -17.970 1.00 50.21  ?  4346 LYS   C O      1 
ATOM   5939 C  CB     . LYS   B  2 94  ? 92.817  -11.672 -15.625 1.00 46.73  ?  4346 LYS   C CB     1 
ATOM   5940 C  CG     . LYS   B  2 94  ? 91.481  -11.526 -14.924 1.00 44.15  ?  4346 LYS   C CG     1 
ATOM   5941 C  CD     . LYS   B  2 94  ? 91.317  -10.094 -14.469 1.00 48.35  ?  4346 LYS   C CD     1 
ATOM   5942 C  CE     . LYS   B  2 94  ? 90.115  -9.974  -13.553 1.00 47.53  ?  4346 LYS   C CE     1 
ATOM   5943 N  NZ     . LYS   B  2 94  ? 88.894  -9.872  -14.399 1.00 61.99  ?  4346 LYS   C NZ     1 
ATOM   5944 H  H      . LYS   B  2 94  ? 94.635  -12.300 -17.100 1.00 55.00  ?  4346 LYS   C H      1 
ATOM   5945 H  HA     . LYS   B  2 94  ? 93.335  -13.600 -15.227 1.00 53.05  ?  4346 LYS   C HA     1 
ATOM   5946 H  HB2    . LYS   B  2 94  ? 93.501  -11.348 -15.019 1.00 56.60  ?  4346 LYS   C HB2    1 
ATOM   5947 H  HB3    . LYS   B  2 94  ? 92.790  -11.118 -16.421 1.00 56.60  ?  4346 LYS   C HB3    1 
ATOM   5948 H  HG2    . LYS   B  2 94  ? 90.761  -11.747 -15.535 1.00 53.50  ?  4346 LYS   C HG2    1 
ATOM   5949 H  HG3    . LYS   B  2 94  ? 91.449  -12.109 -14.149 1.00 53.50  ?  4346 LYS   C HG3    1 
ATOM   5950 H  HD2    . LYS   B  2 94  ? 92.107  -9.813  -13.983 1.00 58.54  ?  4346 LYS   C HD2    1 
ATOM   5951 H  HD3    . LYS   B  2 94  ? 91.179  -9.520  -15.239 1.00 58.54  ?  4346 LYS   C HD3    1 
ATOM   5952 H  HE2    . LYS   B  2 94  ? 90.046  -10.759 -12.987 1.00 57.55  ?  4346 LYS   C HE2    1 
ATOM   5953 H  HE3    . LYS   B  2 94  ? 90.191  -9.177  -13.005 1.00 57.55  ?  4346 LYS   C HE3    1 
ATOM   5954 H  HZ1    . LYS   B  2 94  ? 88.947  -9.156  -14.925 1.00 74.91  ?  4346 LYS   C HZ1    1 
ATOM   5955 H  HZ2    . LYS   B  2 94  ? 88.814  -10.598 -14.907 1.00 74.91  ?  4346 LYS   C HZ2    1 
ATOM   5956 H  HZ3    . LYS   B  2 94  ? 88.172  -9.799  -13.884 1.00 74.91  ?  4346 LYS   C HZ3    1 
ATOM   5957 N  N      . GLY   B  2 95  ? 91.326  -14.638 -16.059 1.00 45.95  ?  4347 GLY   C N      1 
ATOM   5958 C  CA     . GLY   B  2 95  ? 90.242  -15.406 -16.629 1.00 42.02  ?  4347 GLY   C CA     1 
ATOM   5959 C  C      . GLY   B  2 95  ? 90.661  -16.627 -17.412 1.00 39.97  ?  4347 GLY   C C      1 
ATOM   5960 O  O      . GLY   B  2 95  ? 89.794  -17.313 -17.959 1.00 43.14  ?  4347 GLY   C O      1 
ATOM   5961 H  H      . GLY   B  2 95  ? 91.466  -14.798 -15.226 1.00 55.66  ?  4347 GLY   C H      1 
ATOM   5962 H  HA2    . GLY   B  2 95  ? 89.662  -15.702 -15.910 1.00 50.95  ?  4347 GLY   C HA2    1 
ATOM   5963 H  HA3    . GLY   B  2 95  ? 89.737  -14.832 -17.226 1.00 50.95  ?  4347 GLY   C HA3    1 
ATOM   5964 N  N      . LYS   B  2 96  ? 91.953  -16.925 -17.473 1.00 42.94  ?  4348 LYS   C N      1 
ATOM   5965 C  CA     . LYS   B  2 96  ? 92.461  -18.066 -18.210 1.00 47.76  ?  4348 LYS   C CA     1 
ATOM   5966 C  C      . LYS   B  2 96  ? 93.302  -18.922 -17.260 1.00 37.05  ?  4348 LYS   C C      1 
ATOM   5967 O  O      . LYS   B  2 96  ? 93.315  -18.722 -16.034 1.00 40.45  ?  4348 LYS   C O      1 
ATOM   5968 C  CB     . LYS   B  2 96  ? 93.272  -17.592 -19.427 1.00 42.20  ?  4348 LYS   C CB     1 
ATOM   5969 C  CG     . LYS   B  2 96  ? 92.424  -16.963 -20.514 1.00 48.10  ?  4348 LYS   C CG     1 
ATOM   5970 C  CD     . LYS   B  2 96  ? 93.301  -16.216 -21.521 1.00 57.16  ?  4348 LYS   C CD     1 
ATOM   5971 C  CE     . LYS   B  2 96  ? 92.468  -15.372 -22.481 1.00 59.01  ?  4348 LYS   C CE     1 
ATOM   5972 N  NZ     . LYS   B  2 96  ? 92.468  -13.954 -22.098 1.00 73.28  ?  4348 LYS   C NZ     1 
ATOM   5973 H  H      . LYS   B  2 96  ? 92.568  -16.466 -17.084 1.00 52.05  ?  4348 LYS   C H      1 
ATOM   5974 H  HA     . LYS   B  2 96  ? 91.720  -18.600 -18.534 1.00 57.83  ?  4348 LYS   C HA     1 
ATOM   5975 H  HB2    . LYS   B  2 96  ? 93.918  -16.929 -19.134 1.00 51.16  ?  4348 LYS   C HB2    1 
ATOM   5976 H  HB3    . LYS   B  2 96  ? 93.731  -18.354 -19.813 1.00 51.16  ?  4348 LYS   C HB3    1 
ATOM   5977 H  HG2    . LYS   B  2 96  ? 91.935  -17.655 -20.985 1.00 58.24  ?  4348 LYS   C HG2    1 
ATOM   5978 H  HG3    . LYS   B  2 96  ? 91.805  -16.331 -20.117 1.00 58.24  ?  4348 LYS   C HG3    1 
ATOM   5979 H  HD2    . LYS   B  2 96  ? 93.905  -15.626 -21.044 1.00 69.12  ?  4348 LYS   C HD2    1 
ATOM   5980 H  HD3    . LYS   B  2 96  ? 93.807  -16.858 -22.043 1.00 69.12  ?  4348 LYS   C HD3    1 
ATOM   5981 H  HE2    . LYS   B  2 96  ? 92.837  -15.445 -23.375 1.00 71.33  ?  4348 LYS   C HE2    1 
ATOM   5982 H  HE3    . LYS   B  2 96  ? 91.551  -15.689 -22.473 1.00 71.33  ?  4348 LYS   C HE3    1 
ATOM   5983 H  HZ1    . LYS   B  2 96  ? 91.969  -13.485 -22.667 1.00 88.45  ?  4348 LYS   C HZ1    1 
ATOM   5984 H  HZ2    . LYS   B  2 96  ? 92.137  -13.860 -21.278 1.00 88.45  ?  4348 LYS   C HZ2    1 
ATOM   5985 H  HZ3    . LYS   B  2 96  ? 93.299  -13.635 -22.113 1.00 88.45  ?  4348 LYS   C HZ3    1 
ATOM   5986 N  N      . TYR   B  2 97  ? 94.015  -19.876 -17.828 1.00 44.85  ?  4349 TYR   C N      1 
ATOM   5987 C  CA     . TYR   B  2 97  ? 94.875  -20.778 -17.089 1.00 41.81  ?  4349 TYR   C CA     1 
ATOM   5988 C  C      . TYR   B  2 97  ? 96.228  -20.803 -17.755 1.00 37.06  ?  4349 TYR   C C      1 
ATOM   5989 O  O      . TYR   B  2 97  ? 96.319  -20.874 -18.982 1.00 46.42  ?  4349 TYR   C O      1 
ATOM   5990 C  CB     . TYR   B  2 97  ? 94.263  -22.160 -17.037 1.00 35.79  ?  4349 TYR   C CB     1 
ATOM   5991 C  CG     . TYR   B  2 97  ? 92.960  -22.080 -16.330 1.00 41.38  ?  4349 TYR   C CG     1 
ATOM   5992 C  CD1    . TYR   B  2 97  ? 92.889  -22.100 -14.943 1.00 37.14  ?  4349 TYR   C CD1    1 
ATOM   5993 C  CD2    . TYR   B  2 97  ? 91.796  -21.874 -17.037 1.00 40.42  ?  4349 TYR   C CD2    1 
ATOM   5994 C  CE1    . TYR   B  2 97  ? 91.673  -22.006 -14.301 1.00 35.66  ?  4349 TYR   C CE1    1 
ATOM   5995 C  CE2    . TYR   B  2 97  ? 90.586  -21.755 -16.407 1.00 42.18  ?  4349 TYR   C CE2    1 
ATOM   5996 C  CZ     . TYR   B  2 97  ? 90.530  -21.824 -15.038 1.00 38.68  ?  4349 TYR   C CZ     1 
ATOM   5997 O  OH     . TYR   B  2 97  ? 89.314  -21.712 -14.410 1.00 40.79  ?  4349 TYR   C OH     1 
ATOM   5998 H  H      . TYR   B  2 97  ? 94.018  -20.026 -18.675 1.00 54.34  ?  4349 TYR   C H      1 
ATOM   5999 H  HA     . TYR   B  2 97  ? 95.000  -20.469 -16.177 1.00 50.70  ?  4349 TYR   C HA     1 
ATOM   6000 H  HB2    . TYR   B  2 97  ? 94.116  -22.491 -17.937 1.00 43.47  ?  4349 TYR   C HB2    1 
ATOM   6001 H  HB3    . TYR   B  2 97  ? 94.849  -22.764 -16.554 1.00 43.47  ?  4349 TYR   C HB3    1 
ATOM   6002 H  HD1    . TYR   B  2 97  ? 93.669  -22.177 -14.442 1.00 45.09  ?  4349 TYR   C HD1    1 
ATOM   6003 H  HD2    . TYR   B  2 97  ? 91.832  -21.815 -17.964 1.00 49.03  ?  4349 TYR   C HD2    1 
ATOM   6004 H  HE1    . TYR   B  2 97  ? 91.627  -22.066 -13.374 1.00 43.31  ?  4349 TYR   C HE1    1 
ATOM   6005 H  HE2    . TYR   B  2 97  ? 89.810  -21.627 -16.902 1.00 51.13  ?  4349 TYR   C HE2    1 
ATOM   6006 H  HH     . TYR   B  2 97  ? 89.417  -21.740 -13.577 1.00 49.46  ?  4349 TYR   C HH     1 
ATOM   6007 N  N      . VAL   B  2 98  ? 97.272  -20.681 -16.944 1.00 39.33  ?  4350 VAL   C N      1 
ATOM   6008 C  CA     . VAL   B  2 98  ? 98.638  -20.637 -17.418 1.00 40.75  ?  4350 VAL   C CA     1 
ATOM   6009 C  C      . VAL   B  2 98  ? 99.328  -21.932 -17.012 1.00 42.71  ?  4350 VAL   C C      1 
ATOM   6010 O  O      . VAL   B  2 98  ? 99.141  -22.430 -15.896 1.00 41.38  ?  4350 VAL   C O      1 
ATOM   6011 C  CB     . VAL   B  2 98  ? 99.369  -19.389 -16.881 1.00 41.70  ?  4350 VAL   C CB     1 
ATOM   6012 C  CG1    . VAL   B  2 98  ? 99.500  -19.443 -15.378 1.00 46.48  ?  4350 VAL   C CG1    1 
ATOM   6013 C  CG2    . VAL   B  2 98  ? 100.709 -19.230 -17.571 1.00 49.62  ?  4350 VAL   C CG2    1 
ATOM   6014 H  H      . VAL   B  2 98  ? 97.206  -20.620 -16.089 1.00 47.72  ?  4350 VAL   C H      1 
ATOM   6015 H  HA     . VAL   B  2 98  ? 98.657  -20.592 -18.387 1.00 49.42  ?  4350 VAL   C HA     1 
ATOM   6016 H  HB     . VAL   B  2 98  ? 98.845  -18.598 -17.082 1.00 50.56  ?  4350 VAL   C HB     1 
ATOM   6017 H  HG11   . VAL   B  2 98  ? 99.860  -18.600 -15.062 1.00 56.30  ?  4350 VAL   C HG11   1 
ATOM   6018 H  HG12   . VAL   B  2 98  ? 98.624  -19.596 -14.990 1.00 56.30  ?  4350 VAL   C HG12   1 
ATOM   6019 H  HG13   . VAL   B  2 98  ? 100.098 -20.169 -15.140 1.00 56.30  ?  4350 VAL   C HG13   1 
ATOM   6020 H  HG21   . VAL   B  2 98  ? 101.089 -18.371 -17.329 1.00 60.07  ?  4350 VAL   C HG21   1 
ATOM   6021 H  HG22   . VAL   B  2 98  ? 101.299 -19.945 -17.285 1.00 60.07  ?  4350 VAL   C HG22   1 
ATOM   6022 H  HG23   . VAL   B  2 98  ? 100.577 -19.274 -18.531 1.00 60.07  ?  4350 VAL   C HG23   1 
ATOM   6023 N  N      . GLN   B  2 99  ? 100.055 -22.515 -17.955 1.00 47.57  ?  4351 GLN   C N      1 
ATOM   6024 C  CA     . GLN   B  2 99  ? 100.780 -23.756 -17.752 1.00 44.55  ?  4351 GLN   C CA     1 
ATOM   6025 C  C      . GLN   B  2 99  ? 102.234 -23.400 -17.476 1.00 44.18  ?  4351 GLN   C C      1 
ATOM   6026 O  O      . GLN   B  2 99  ? 102.836 -22.634 -18.231 1.00 48.91  ?  4351 GLN   C O      1 
ATOM   6027 C  CB     . GLN   B  2 99  ? 100.657 -24.660 -18.977 1.00 42.01  ?  4351 GLN   C CB     1 
ATOM   6028 C  CG     . GLN   B  2 99  ? 99.384  -25.502 -19.041 1.00 42.95  ?  4351 GLN   C CG     1 
ATOM   6029 C  CD     . GLN   B  2 99  ? 98.099  -24.718 -19.083 1.00 43.19  ?  4351 GLN   C CD     1 
ATOM   6030 O  OE1    . GLN   B  2 99  ? 97.235  -24.880 -18.223 1.00 44.13  ?  4351 GLN   C OE1    1 
ATOM   6031 N  NE2    . GLN   B  2 99  ? 97.949  -23.876 -20.094 1.00 44.35  ?  4351 GLN   C NE2    1 
ATOM   6032 H  H      . GLN   B  2 99  ? 100.147 -22.198 -18.749 1.00 57.61  ?  4351 GLN   C H      1 
ATOM   6033 H  HA     . GLN   B  2 99  ? 100.424 -24.250 -16.996 1.00 53.98  ?  4351 GLN   C HA     1 
ATOM   6034 H  HB2    . GLN   B  2 99  ? 100.677 -24.103 -19.771 1.00 50.93  ?  4351 GLN   C HB2    1 
ATOM   6035 H  HB3    . GLN   B  2 99  ? 101.410 -25.272 -18.982 1.00 50.93  ?  4351 GLN   C HB3    1 
ATOM   6036 H  HG2    . GLN   B  2 99  ? 99.417  -26.047 -19.843 1.00 52.06  ?  4351 GLN   C HG2    1 
ATOM   6037 H  HG3    . GLN   B  2 99  ? 99.352  -26.070 -18.256 1.00 52.06  ?  4351 GLN   C HG3    1 
ATOM   6038 H  HE21   . GLN   B  2 99  ? 98.569  -23.798 -20.685 1.00 53.74  ?  4351 GLN   C HE21   1 
ATOM   6039 H  HE22   . GLN   B  2 99  ? 97.231  -23.406 -20.160 1.00 53.74  ?  4351 GLN   C HE22   1 
ATOM   6040 N  N      . ILE   B  2 100 ? 102.774 -23.923 -16.379 1.00 40.39  ?  4352 ILE   C N      1 
ATOM   6041 C  CA     . ILE   B  2 100 ? 104.109 -23.589 -15.904 1.00 41.36  ?  4352 ILE   C CA     1 
ATOM   6042 C  C      . ILE   B  2 100 ? 104.927 -24.872 -15.846 1.00 43.56  ?  4352 ILE   C C      1 
ATOM   6043 O  O      . ILE   B  2 100 ? 104.488 -25.847 -15.232 1.00 48.63  ?  4352 ILE   C O      1 
ATOM   6044 C  CB     . ILE   B  2 100 ? 104.088 -22.906 -14.524 1.00 45.64  ?  4352 ILE   C CB     1 
ATOM   6045 C  CG1    . ILE   B  2 100 ? 103.262 -21.618 -14.587 1.00 42.40  ?  4352 ILE   C CG1    1 
ATOM   6046 C  CG2    . ILE   B  2 100 ? 105.509 -22.603 -14.067 1.00 45.13  ?  4352 ILE   C CG2    1 
ATOM   6047 C  CD1    . ILE   B  2 100 ? 103.857 -20.527 -15.466 1.00 45.59  ?  4352 ILE   C CD1    1 
ATOM   6048 H  H      . ILE   B  2 100 ? 102.370 -24.493 -15.877 1.00 48.99  ?  4352 ILE   C H      1 
ATOM   6049 H  HA     . ILE   B  2 100 ? 104.533 -22.991 -16.539 1.00 50.16  ?  4352 ILE   C HA     1 
ATOM   6050 H  HB     . ILE   B  2 100 ? 103.676 -23.509 -13.885 1.00 55.29  ?  4352 ILE   C HB     1 
ATOM   6051 H  HG12   . ILE   B  2 100 ? 102.384 -21.831 -14.939 1.00 51.41  ?  4352 ILE   C HG12   1 
ATOM   6052 H  HG13   . ILE   B  2 100 ? 103.182 -21.259 -13.689 1.00 51.41  ?  4352 ILE   C HG13   1 
ATOM   6053 H  HG21   . ILE   B  2 100 ? 105.475 -21.989 -13.317 1.00 54.68  ?  4352 ILE   C HG21   1 
ATOM   6054 H  HG22   . ILE   B  2 100 ? 105.937 -23.430 -13.798 1.00 54.68  ?  4352 ILE   C HG22   1 
ATOM   6055 H  HG23   . ILE   B  2 100 ? 105.997 -22.200 -14.802 1.00 54.68  ?  4352 ILE   C HG23   1 
ATOM   6056 H  HD11   . ILE   B  2 100 ? 103.261 -19.762 -15.467 1.00 55.24  ?  4352 ILE   C HD11   1 
ATOM   6057 H  HD12   . ILE   B  2 100 ? 104.722 -20.271 -15.109 1.00 55.24  ?  4352 ILE   C HD12   1 
ATOM   6058 H  HD13   . ILE   B  2 100 ? 103.959 -20.869 -16.368 1.00 55.24  ?  4352 ILE   C HD13   1 
ATOM   6059 N  N      . PRO   B  2 101 ? 106.095 -24.935 -16.486 1.00 50.38  ?  4353 PRO   C N      1 
ATOM   6060 C  CA     . PRO   B  2 101 ? 106.955 -26.117 -16.326 1.00 46.78  ?  4353 PRO   C CA     1 
ATOM   6061 C  C      . PRO   B  2 101 ? 107.093 -26.467 -14.849 1.00 42.84  ?  4353 PRO   C C      1 
ATOM   6062 O  O      . PRO   B  2 101 ? 107.330 -25.604 -14.006 1.00 47.58  ?  4353 PRO   C O      1 
ATOM   6063 C  CB     . PRO   B  2 101 ? 108.287 -25.678 -16.948 1.00 50.23  ?  4353 PRO   C CB     1 
ATOM   6064 C  CG     . PRO   B  2 101 ? 107.979 -24.536 -17.812 1.00 49.96  ?  4353 PRO   C CG     1 
ATOM   6065 C  CD     . PRO   B  2 101 ? 106.600 -24.019 -17.527 1.00 47.25  ?  4353 PRO   C CD     1 
ATOM   6066 H  HA     . PRO   B  2 101 ? 106.614 -26.878 -16.821 1.00 56.66  ?  4353 PRO   C HA     1 
ATOM   6067 H  HB2    . PRO   B  2 101 ? 108.904 -25.419 -16.246 1.00 60.80  ?  4353 PRO   C HB2    1 
ATOM   6068 H  HB3    . PRO   B  2 101 ? 108.660 -26.408 -17.466 1.00 60.80  ?  4353 PRO   C HB3    1 
ATOM   6069 H  HG2    . PRO   B  2 101 ? 108.631 -23.837 -17.643 1.00 60.47  ?  4353 PRO   C HG2    1 
ATOM   6070 H  HG3    . PRO   B  2 101 ? 108.035 -24.825 -18.736 1.00 60.47  ?  4353 PRO   C HG3    1 
ATOM   6071 H  HD2    . PRO   B  2 101 ? 106.635 -23.108 -17.196 1.00 57.22  ?  4353 PRO   C HD2    1 
ATOM   6072 H  HD3    . PRO   B  2 101 ? 106.045 -24.063 -18.321 1.00 57.22  ?  4353 PRO   C HD3    1 
ATOM   6073 N  N      . THR   B  2 102 ? 106.920 -27.750 -14.534 1.00 46.73  ?  4354 THR   C N      1 
ATOM   6074 C  CA     . THR   B  2 102 ? 106.912 -28.171 -13.139 1.00 46.53  ?  4354 THR   C CA     1 
ATOM   6075 C  C      . THR   B  2 102 ? 108.201 -27.772 -12.433 1.00 48.13  ?  4354 THR   C C      1 
ATOM   6076 O  O      . THR   B  2 102 ? 108.210 -27.567 -11.217 1.00 53.80  ?  4354 THR   C O      1 
ATOM   6077 C  CB     . THR   B  2 102 ? 106.693 -29.676 -13.081 1.00 46.22  ?  4354 THR   C CB     1 
ATOM   6078 O  OG1    . THR   B  2 102 ? 105.499 -29.997 -13.806 1.00 55.46  ?  4354 THR   C OG1    1 
ATOM   6079 C  CG2    . THR   B  2 102 ? 106.525 -30.138 -11.669 1.00 49.34  ?  4354 THR   C CG2    1 
ATOM   6080 H  H      . THR   B  2 102 ? 106.806 -28.386 -15.102 1.00 56.60  ?  4354 THR   C H      1 
ATOM   6081 H  HA     . THR   B  2 102 ? 106.183 -27.741 -12.665 1.00 56.35  ?  4354 THR   C HA     1 
ATOM   6082 H  HB     . THR   B  2 102 ? 107.460 -30.129 -13.463 1.00 55.98  ?  4354 THR   C HB     1 
ATOM   6083 H  HG1    . THR   B  2 102 ? 105.363 -30.825 -13.783 1.00 67.08  ?  4354 THR   C HG1    1 
ATOM   6084 H  HG21   . THR   B  2 102 ? 106.286 -31.078 -11.654 1.00 59.73  ?  4354 THR   C HG21   1 
ATOM   6085 H  HG22   . THR   B  2 102 ? 107.353 -30.015 -11.179 1.00 59.73  ?  4354 THR   C HG22   1 
ATOM   6086 H  HG23   . THR   B  2 102 ? 105.824 -29.628 -11.234 1.00 59.73  ?  4354 THR   C HG23   1 
ATOM   6087 N  N      . THR   B  2 103 ? 109.286 -27.614 -13.187 1.00 57.36  ?  4355 THR   C N      1 
ATOM   6088 C  CA     . THR   B  2 103 ? 110.559 -27.211 -12.613 1.00 57.91  ?  4355 THR   C CA     1 
ATOM   6089 C  C      . THR   B  2 103 ? 110.613 -25.731 -12.269 1.00 53.71  ?  4355 THR   C C      1 
ATOM   6090 O  O      . THR   B  2 103 ? 111.462 -25.337 -11.462 1.00 54.33  ?  4355 THR   C O      1 
ATOM   6091 C  CB     . THR   B  2 103 ? 111.670 -27.576 -13.583 1.00 50.26  ?  4355 THR   C CB     1 
ATOM   6092 O  OG1    . THR   B  2 103 ? 111.283 -27.169 -14.900 1.00 52.38  ?  4355 THR   C OG1    1 
ATOM   6093 C  CG2    . THR   B  2 103 ? 111.869 -29.086 -13.586 1.00 55.30  ?  4355 THR   C CG2    1 
ATOM   6094 H  H      . THR   B  2 103 ? 109.309 -27.736 -14.038 1.00 69.35  ?  4355 THR   C H      1 
ATOM   6095 H  HA     . THR   B  2 103 ? 110.709 -27.690 -11.783 1.00 70.01  ?  4355 THR   C HA     1 
ATOM   6096 H  HB     . THR   B  2 103 ? 112.498 -27.142 -13.325 1.00 60.84  ?  4355 THR   C HB     1 
ATOM   6097 H  HG1    . THR   B  2 103 ? 111.903 -27.327 -15.443 1.00 63.38  ?  4355 THR   C HG1    1 
ATOM   6098 H  HG21   . THR   B  2 103 ? 112.591 -29.324 -14.189 1.00 66.88  ?  4355 THR   C HG21   1 
ATOM   6099 H  HG22   . THR   B  2 103 ? 112.091 -29.393 -12.693 1.00 66.88  ?  4355 THR   C HG22   1 
ATOM   6100 H  HG23   . THR   B  2 103 ? 111.057 -29.528 -13.878 1.00 66.88  ?  4355 THR   C HG23   1 
ATOM   6101 N  N      . CYS   B  2 104 ? 109.725 -24.916 -12.833 1.00 53.68  ?  4356 CYS   C N      1 
ATOM   6102 C  CA     . CYS   B  2 104 ? 109.666 -23.497 -12.508 1.00 50.43  ?  4356 CYS   C CA     1 
ATOM   6103 C  C      . CYS   B  2 104 ? 108.430 -23.128 -11.711 1.00 49.27  ?  4356 CYS   C C      1 
ATOM   6104 O  O      . CYS   B  2 104 ? 108.174 -21.938 -11.512 1.00 54.35  ?  4356 CYS   C O      1 
ATOM   6105 C  CB     . CYS   B  2 104 ? 109.714 -22.660 -13.784 1.00 48.68  ?  4356 CYS   C CB     1 
ATOM   6106 S  SG     . CYS   B  2 104 ? 110.992 -23.192 -14.913 1.00 52.65  ?  4356 CYS   C SG     1 
ATOM   6107 H  H      . CYS   B  2 104 ? 109.141 -25.166 -13.413 1.00 64.93  ?  4356 CYS   C H      1 
ATOM   6108 H  HA     . CYS   B  2 104 ? 110.444 -23.281 -11.971 1.00 61.04  ?  4356 CYS   C HA     1 
ATOM   6109 H  HB2    . CYS   B  2 104 ? 108.861 -22.731 -14.240 1.00 58.93  ?  4356 CYS   C HB2    1 
ATOM   6110 H  HB3    . CYS   B  2 104 ? 109.888 -21.735 -13.548 1.00 58.93  ?  4356 CYS   C HB3    1 
ATOM   6111 H  HG     . CYS   B  2 104 ? 110.952 -22.507 -15.898 1.00 63.70  ?  4356 CYS   C HG     1 
ATOM   6112 N  N      . ALA   B  2 105 ? 107.651 -24.103 -11.260 1.00 51.49  ?  4357 ALA   C N      1 
ATOM   6113 C  CA     . ALA   B  2 105 ? 106.378 -23.790 -10.623 1.00 48.03  ?  4357 ALA   C CA     1 
ATOM   6114 C  C      . ALA   B  2 105 ? 106.530 -23.241 -9.214  1.00 45.40  ?  4357 ALA   C C      1 
ATOM   6115 O  O      . ALA   B  2 105 ? 105.523 -22.904 -8.589  1.00 51.69  ?  4357 ALA   C O      1 
ATOM   6116 C  CB     . ALA   B  2 105 ? 105.485 -25.028 -10.599 1.00 47.94  ?  4357 ALA   C CB     1 
ATOM   6117 H  H      . ALA   B  2 105 ? 107.835 -24.941 -11.309 1.00 62.31  ?  4357 ALA   C H      1 
ATOM   6118 H  HA     . ALA   B  2 105 ? 105.932 -23.112 -11.154 1.00 58.15  ?  4357 ALA   C HA     1 
ATOM   6119 H  HB1    . ALA   B  2 105 ? 104.645 -24.803 -10.169 1.00 58.05  ?  4357 ALA   C HB1    1 
ATOM   6120 H  HB2    . ALA   B  2 105 ? 105.323 -25.319 -11.510 1.00 58.05  ?  4357 ALA   C HB2    1 
ATOM   6121 H  HB3    . ALA   B  2 105 ? 105.933 -25.731 -10.102 1.00 58.05  ?  4357 ALA   C HB3    1 
ATOM   6122 N  N      . ASN   B  2 106 ? 107.754 -23.119 -8.706  1.00 51.11  ?  4358 ASN   C N      1 
ATOM   6123 C  CA     . ASN   B  2 106 ? 107.960 -22.402 -7.450  1.00 45.44  ?  4358 ASN   C CA     1 
ATOM   6124 C  C      . ASN   B  2 106 ? 107.781 -20.893 -7.612  1.00 49.98  ?  4358 ASN   C C      1 
ATOM   6125 O  O      . ASN   B  2 106 ? 107.653 -20.186 -6.610  1.00 53.26  ?  4358 ASN   C O      1 
ATOM   6126 C  CB     . ASN   B  2 106 ? 109.351 -22.689 -6.903  1.00 47.03  ?  4358 ASN   C CB     1 
ATOM   6127 C  CG     . ASN   B  2 106 ? 110.439 -22.329 -7.879  1.00 61.64  ?  4358 ASN   C CG     1 
ATOM   6128 O  OD1    . ASN   B  2 106 ? 110.492 -22.853 -8.982  1.00 55.86  ?  4358 ASN   C OD1    1 
ATOM   6129 N  ND2    . ASN   B  2 106 ? 111.312 -21.421 -7.480  1.00 63.38  ?  4358 ASN   C ND2    1 
ATOM   6130 H  H      . ASN   B  2 106 ? 108.469 -23.436 -9.062  1.00 61.86  ?  4358 ASN   C H      1 
ATOM   6131 H  HA     . ASN   B  2 106 ? 107.314 -22.721 -6.800  1.00 55.05  ?  4358 ASN   C HA     1 
ATOM   6132 H  HB2    . ASN   B  2 106 ? 109.488 -22.169 -6.095  1.00 56.95  ?  4358 ASN   C HB2    1 
ATOM   6133 H  HB3    . ASN   B  2 106 ? 109.425 -23.635 -6.705  1.00 56.95  ?  4358 ASN   C HB3    1 
ATOM   6134 H  HD21   . ASN   B  2 106 ? 111.241 -21.070 -6.699  1.00 76.57  ?  4358 ASN   C HD21   1 
ATOM   6135 H  HD22   . ASN   B  2 106 ? 111.952 -21.182 -8.003  1.00 76.57  ?  4358 ASN   C HD22   1 
ATOM   6136 N  N      . ASP   B  2 107 ? 107.790 -20.392 -8.848  1.00 49.53  ?  4359 ASP   C N      1 
ATOM   6137 C  CA     . ASP   B  2 107 ? 107.707 -18.961 -9.122  1.00 48.58  ?  4359 ASP   C CA     1 
ATOM   6138 C  C      . ASP   B  2 107 ? 106.934 -18.772 -10.416 1.00 43.04  ?  4359 ASP   C C      1 
ATOM   6139 O  O      . ASP   B  2 107 ? 107.498 -18.398 -11.450 1.00 44.19  ?  4359 ASP   C O      1 
ATOM   6140 C  CB     . ASP   B  2 107 ? 109.101 -18.348 -9.227  1.00 55.94  ?  4359 ASP   C CB     1 
ATOM   6141 C  CG     . ASP   B  2 107 ? 109.062 -16.855 -9.422  1.00 54.54  ?  4359 ASP   C CG     1 
ATOM   6142 O  OD1    . ASP   B  2 107 ? 107.968 -16.265 -9.352  1.00 56.67  ?  4359 ASP   C OD1    1 
ATOM   6143 O  OD2    . ASP   B  2 107 ? 110.134 -16.257 -9.606  1.00 57.49  ?  4359 ASP   C OD2    1 
ATOM   6144 H  H      . ASP   B  2 107 ? 107.844 -20.874 -9.559  1.00 59.96  ?  4359 ASP   C H      1 
ATOM   6145 H  HA     . ASP   B  2 107 ? 107.233 -18.517 -8.401  1.00 58.82  ?  4359 ASP   C HA     1 
ATOM   6146 H  HB2    . ASP   B  2 107 ? 109.590 -18.531 -8.409  1.00 67.65  ?  4359 ASP   C HB2    1 
ATOM   6147 H  HB3    . ASP   B  2 107 ? 109.563 -18.739 -9.985  1.00 67.65  ?  4359 ASP   C HB3    1 
ATOM   6148 N  N      . PRO   B  2 108 ? 105.627 -19.053 -10.403 1.00 45.09  ?  4360 PRO   C N      1 
ATOM   6149 C  CA     . PRO   B  2 108 ? 104.837 -18.863 -11.636 1.00 44.55  ?  4360 PRO   C CA     1 
ATOM   6150 C  C      . PRO   B  2 108 ? 104.832 -17.424 -12.125 1.00 43.88  ?  4360 PRO   C C      1 
ATOM   6151 O  O      . PRO   B  2 108 ? 104.832 -17.176 -13.340 1.00 47.86  ?  4360 PRO   C O      1 
ATOM   6152 C  CB     . PRO   B  2 108 ? 103.431 -19.337 -11.225 1.00 40.40  ?  4360 PRO   C CB     1 
ATOM   6153 C  CG     . PRO   B  2 108 ? 103.652 -20.221 -10.030 1.00 47.83  ?  4360 PRO   C CG     1 
ATOM   6154 C  CD     . PRO   B  2 108 ? 104.813 -19.609 -9.304  1.00 49.05  ?  4360 PRO   C CD     1 
ATOM   6155 H  HA     . PRO   B  2 108 ? 105.175 -19.441 -12.338 1.00 53.98  ?  4360 PRO   C HA     1 
ATOM   6156 H  HB2    . PRO   B  2 108 ? 102.880 -18.573 -10.994 1.00 49.01  ?  4360 PRO   C HB2    1 
ATOM   6157 H  HB3    . PRO   B  2 108 ? 103.024 -19.832 -11.953 1.00 49.01  ?  4360 PRO   C HB3    1 
ATOM   6158 H  HG2    . PRO   B  2 108 ? 102.859 -20.228 -9.473  1.00 57.92  ?  4360 PRO   C HG2    1 
ATOM   6159 H  HG3    . PRO   B  2 108 ? 103.862 -21.122 -10.321 1.00 57.92  ?  4360 PRO   C HG3    1 
ATOM   6160 H  HD2    . PRO   B  2 108 ? 104.516 -18.908 -8.702  1.00 59.38  ?  4360 PRO   C HD2    1 
ATOM   6161 H  HD3    . PRO   B  2 108 ? 105.308 -20.282 -8.810  1.00 59.38  ?  4360 PRO   C HD3    1 
ATOM   6162 N  N      . VAL   B  2 109 ? 104.806 -16.457 -11.206 1.00 45.76  ?  4361 VAL   C N      1 
ATOM   6163 C  CA     . VAL   B  2 109 ? 104.780 -15.061 -11.628 1.00 49.07  ?  4361 VAL   C CA     1 
ATOM   6164 C  C      . VAL   B  2 109 ? 106.071 -14.716 -12.356 1.00 49.06  ?  4361 VAL   C C      1 
ATOM   6165 O  O      . VAL   B  2 109 ? 106.051 -14.154 -13.457 1.00 48.22  ?  4361 VAL   C O      1 
ATOM   6166 C  CB     . VAL   B  2 109 ? 104.546 -14.118 -10.437 1.00 46.40  ?  4361 VAL   C CB     1 
ATOM   6167 C  CG1    . VAL   B  2 109 ? 104.542 -12.686 -10.937 1.00 44.69  ?  4361 VAL   C CG1    1 
ATOM   6168 C  CG2    . VAL   B  2 109 ? 103.245 -14.450 -9.740  1.00 45.12  ?  4361 VAL   C CG2    1 
ATOM   6169 H  H      . VAL   B  2 109 ? 104.801 -16.582 -10.355 1.00 55.43  ?  4361 VAL   C H      1 
ATOM   6170 H  HA     . VAL   B  2 109 ? 104.035 -14.947 -12.239 1.00 59.41  ?  4361 VAL   C HA     1 
ATOM   6171 H  HB     . VAL   B  2 109 ? 105.256 -14.226 -9.785  1.00 56.21  ?  4361 VAL   C HB     1 
ATOM   6172 H  HG11   . VAL   B  2 109 ? 104.081 -12.127 -10.292 1.00 54.15  ?  4361 VAL   C HG11   1 
ATOM   6173 H  HG12   . VAL   B  2 109 ? 105.458 -12.386 -11.041 1.00 54.15  ?  4361 VAL   C HG12   1 
ATOM   6174 H  HG13   . VAL   B  2 109 ? 104.083 -12.652 -11.792 1.00 54.15  ?  4361 VAL   C HG13   1 
ATOM   6175 H  HG21   . VAL   B  2 109 ? 103.123 -13.845 -8.992  1.00 54.66  ?  4361 VAL   C HG21   1 
ATOM   6176 H  HG22   . VAL   B  2 109 ? 102.514 -14.348 -10.370 1.00 54.66  ?  4361 VAL   C HG22   1 
ATOM   6177 H  HG23   . VAL   B  2 109 ? 103.281 -15.366 -9.422  1.00 54.66  ?  4361 VAL   C HG23   1 
ATOM   6178 N  N      . GLY   B  2 110 ? 107.212 -15.045 -11.752 1.00 48.59  ?  4362 GLY   C N      1 
ATOM   6179 C  CA     . GLY   B  2 110 ? 108.477 -14.823 -12.425 1.00 48.44  ?  4362 GLY   C CA     1 
ATOM   6180 C  C      . GLY   B  2 110 ? 108.540 -15.513 -13.768 1.00 50.45  ?  4362 GLY   C C      1 
ATOM   6181 O  O      . GLY   B  2 110 ? 108.995 -14.933 -14.754 1.00 53.81  ?  4362 GLY   C O      1 
ATOM   6182 H  H      . GLY   B  2 110 ? 107.275 -15.393 -10.968 1.00 58.82  ?  4362 GLY   C H      1 
ATOM   6183 H  HA2    . GLY   B  2 110 ? 108.604 -13.871 -12.564 1.00 58.66  ?  4362 GLY   C HA2    1 
ATOM   6184 H  HA3    . GLY   B  2 110 ? 109.199 -15.160 -11.872 1.00 58.66  ?  4362 GLY   C HA3    1 
ATOM   6185 N  N      . PHE   B  2 111 ? 108.059 -16.757 -13.839 1.00 49.82  ?  4363 PHE   C N      1 
ATOM   6186 C  CA     . PHE   B  2 111 ? 108.068 -17.451 -15.122 1.00 47.30  ?  4363 PHE   C CA     1 
ATOM   6187 C  C      . PHE   B  2 111 ? 107.291 -16.668 -16.176 1.00 45.41  ?  4363 PHE   C C      1 
ATOM   6188 O  O      . PHE   B  2 111 ? 107.824 -16.337 -17.240 1.00 53.67  ?  4363 PHE   C O      1 
ATOM   6189 C  CB     . PHE   B  2 111 ? 107.491 -18.862 -14.983 1.00 46.96  ?  4363 PHE   C CB     1 
ATOM   6190 C  CG     . PHE   B  2 111 ? 107.689 -19.698 -16.208 1.00 43.02  ?  4363 PHE   C CG     1 
ATOM   6191 C  CD1    . PHE   B  2 111 ? 108.848 -20.425 -16.379 1.00 42.00  ?  4363 PHE   C CD1    1 
ATOM   6192 C  CD2    . PHE   B  2 111 ? 106.723 -19.740 -17.193 1.00 50.20  ?  4363 PHE   C CD2    1 
ATOM   6193 C  CE1    . PHE   B  2 111 ? 109.038 -21.181 -17.504 1.00 46.74  ?  4363 PHE   C CE1    1 
ATOM   6194 C  CE2    . PHE   B  2 111 ? 106.901 -20.490 -18.317 1.00 45.88  ?  4363 PHE   C CE2    1 
ATOM   6195 C  CZ     . PHE   B  2 111 ? 108.057 -21.214 -18.478 1.00 47.47  ?  4363 PHE   C CZ     1 
ATOM   6196 H  H      . PHE   B  2 111 ? 107.733 -17.204 -13.180 1.00 60.30  ?  4363 PHE   C H      1 
ATOM   6197 H  HA     . PHE   B  2 111 ? 108.991 -17.531 -15.410 1.00 57.28  ?  4363 PHE   C HA     1 
ATOM   6198 H  HB2    . PHE   B  2 111 ? 107.928 -19.309 -14.241 1.00 56.88  ?  4363 PHE   C HB2    1 
ATOM   6199 H  HB3    . PHE   B  2 111 ? 106.538 -18.797 -14.815 1.00 56.88  ?  4363 PHE   C HB3    1 
ATOM   6200 H  HD1    . PHE   B  2 111 ? 109.507 -20.402 -15.723 1.00 50.92  ?  4363 PHE   C HD1    1 
ATOM   6201 H  HD2    . PHE   B  2 111 ? 105.939 -19.251 -17.088 1.00 60.76  ?  4363 PHE   C HD2    1 
ATOM   6202 H  HE1    . PHE   B  2 111 ? 109.822 -21.669 -17.613 1.00 56.61  ?  4363 PHE   C HE1    1 
ATOM   6203 H  HE2    . PHE   B  2 111 ? 106.242 -20.511 -18.973 1.00 55.57  ?  4363 PHE   C HE2    1 
ATOM   6204 H  HZ     . PHE   B  2 111 ? 108.181 -21.727 -19.244 1.00 57.49  ?  4363 PHE   C HZ     1 
ATOM   6205 N  N      . THR   B  2 112 ? 106.019 -16.372 -15.900 1.00 43.93  ?  4364 THR   C N      1 
ATOM   6206 C  CA     . THR   B  2 112 ? 105.191 -15.695 -16.893 1.00 49.24  ?  4364 THR   C CA     1 
ATOM   6207 C  C      . THR   B  2 112 ? 105.805 -14.366 -17.304 1.00 50.25  ?  4364 THR   C C      1 
ATOM   6208 O  O      . THR   B  2 112 ? 105.730 -13.966 -18.475 1.00 53.08  ?  4364 THR   C O      1 
ATOM   6209 C  CB     . THR   B  2 112 ? 103.775 -15.458 -16.352 1.00 52.54  ?  4364 THR   C CB     1 
ATOM   6210 O  OG1    . THR   B  2 112 ? 103.845 -14.695 -15.138 1.00 59.16  ?  4364 THR   C OG1    1 
ATOM   6211 C  CG2    . THR   B  2 112 ? 103.076 -16.782 -16.087 1.00 48.82  ?  4364 THR   C CG2    1 
ATOM   6212 H  H      . THR   B  2 112 ? 105.621 -16.548 -15.158 1.00 53.23  ?  4364 THR   C H      1 
ATOM   6213 H  HA     . THR   B  2 112 ? 105.127 -16.271 -17.671 1.00 59.61  ?  4364 THR   C HA     1 
ATOM   6214 H  HB     . THR   B  2 112 ? 103.255 -14.968 -17.008 1.00 63.57  ?  4364 THR   C HB     1 
ATOM   6215 H  HG1    . THR   B  2 112 ? 104.293 -15.112 -14.562 1.00 71.51  ?  4364 THR   C HG1    1 
ATOM   6216 H  HG21   . THR   B  2 112 ? 102.161 -16.624 -15.808 1.00 59.10  ?  4364 THR   C HG21   1 
ATOM   6217 H  HG22   . THR   B  2 112 ? 103.071 -17.322 -16.893 1.00 59.10  ?  4364 THR   C HG22   1 
ATOM   6218 H  HG23   . THR   B  2 112 ? 103.540 -17.267 -15.386 1.00 59.10  ?  4364 THR   C HG23   1 
ATOM   6219 N  N      . LEU   B  2 113 ? 106.399 -13.660 -16.349 1.00 56.59  ?  4365 LEU   C N      1 
ATOM   6220 C  CA     . LEU   B  2 113 ? 106.957 -12.346 -16.628 1.00 55.40  ?  4365 LEU   C CA     1 
ATOM   6221 C  C      . LEU   B  2 113 ? 108.151 -12.451 -17.562 1.00 57.57  ?  4365 LEU   C C      1 
ATOM   6222 O  O      . LEU   B  2 113 ? 108.274 -11.669 -18.514 1.00 58.76  ?  4365 LEU   C O      1 
ATOM   6223 C  CB     . LEU   B  2 113 ? 107.361 -11.695 -15.311 1.00 48.86  ?  4365 LEU   C CB     1 
ATOM   6224 C  CG     . LEU   B  2 113 ? 107.730 -10.224 -15.272 1.00 56.86  ?  4365 LEU   C CG     1 
ATOM   6225 C  CD1    . LEU   B  2 113 ? 106.437 -9.441  -15.382 1.00 51.09  ?  4365 LEU   C CD1    1 
ATOM   6226 C  CD2    . LEU   B  2 113 ? 108.433 -9.956  -13.973 1.00 64.50  ?  4365 LEU   C CD2    1 
ATOM   6227 H  H      . LEU   B  2 113 ? 106.491 -13.918 -15.534 1.00 68.42  ?  4365 LEU   C H      1 
ATOM   6228 H  HA     . LEU   B  2 113 ? 106.290 -11.790 -17.060 1.00 67.00  ?  4365 LEU   C HA     1 
ATOM   6229 H  HB2    . LEU   B  2 113 ? 106.617 -11.802 -14.698 1.00 59.15  ?  4365 LEU   C HB2    1 
ATOM   6230 H  HB3    . LEU   B  2 113 ? 108.136 -12.175 -14.980 1.00 59.15  ?  4365 LEU   C HB3    1 
ATOM   6231 H  HG     . LEU   B  2 113 ? 108.322 -9.957  -15.992 1.00 68.76  ?  4365 LEU   C HG     1 
ATOM   6232 H  HD11   . LEU   B  2 113 ? 106.640 -8.493  -15.367 1.00 61.83  ?  4365 LEU   C HD11   1 
ATOM   6233 H  HD12   . LEU   B  2 113 ? 105.998 -9.672  -16.215 1.00 61.83  ?  4365 LEU   C HD12   1 
ATOM   6234 H  HD13   . LEU   B  2 113 ? 105.865 -9.669  -14.632 1.00 61.83  ?  4365 LEU   C HD13   1 
ATOM   6235 H  HD21   . LEU   B  2 113 ? 108.681 -9.019  -13.936 1.00 77.92  ?  4365 LEU   C HD21   1 
ATOM   6236 H  HD22   . LEU   B  2 113 ? 107.834 -10.169 -13.240 1.00 77.92  ?  4365 LEU   C HD22   1 
ATOM   6237 H  HD23   . LEU   B  2 113 ? 109.227 -10.511 -13.923 1.00 77.92  ?  4365 LEU   C HD23   1 
ATOM   6238 N  N      . LYS   B  2 114 ? 109.019 -13.428 -17.324 1.00 50.82  ?  4366 LYS   C N      1 
ATOM   6239 C  CA     . LYS   B  2 114 ? 110.288 -13.536 -18.018 1.00 49.69  ?  4366 LYS   C CA     1 
ATOM   6240 C  C      . LYS   B  2 114 ? 110.196 -14.312 -19.325 1.00 49.40  ?  4366 LYS   C C      1 
ATOM   6241 O  O      . LYS   B  2 114 ? 111.212 -14.440 -20.019 1.00 60.09  ?  4366 LYS   C O      1 
ATOM   6242 C  CB     . LYS   B  2 114 ? 111.330 -14.221 -17.119 1.00 50.64  ?  4366 LYS   C CB     1 
ATOM   6243 C  CG     . LYS   B  2 114 ? 111.672 -13.534 -15.807 1.00 62.72  ?  4366 LYS   C CG     1 
ATOM   6244 C  CD     . LYS   B  2 114 ? 112.489 -14.466 -14.927 1.00 68.53  ?  4366 LYS   C CD     1 
ATOM   6245 C  CE     . LYS   B  2 114 ? 113.106 -13.798 -13.722 1.00 61.77  ?  4366 LYS   C CE     1 
ATOM   6246 N  NZ     . LYS   B  2 114 ? 113.813 -14.769 -12.832 1.00 72.10  ?  4366 LYS   C NZ     1 
ATOM   6247 H  H      . LYS   B  2 114 ? 108.889 -14.054 -16.749 1.00 61.50  ?  4366 LYS   C H      1 
ATOM   6248 H  HA     . LYS   B  2 114 ? 110.592 -12.637 -18.219 1.00 60.16  ?  4366 LYS   C HA     1 
ATOM   6249 H  HB2    . LYS   B  2 114 ? 110.997 -15.105 -16.896 1.00 61.29  ?  4366 LYS   C HB2    1 
ATOM   6250 H  HB3    . LYS   B  2 114 ? 112.156 -14.295 -17.623 1.00 61.29  ?  4366 LYS   C HB3    1 
ATOM   6251 H  HG2    . LYS   B  2 114 ? 112.193 -12.735 -15.983 1.00 75.79  ?  4366 LYS   C HG2    1 
ATOM   6252 H  HG3    . LYS   B  2 114 ? 110.855 -13.300 -15.339 1.00 75.79  ?  4366 LYS   C HG3    1 
ATOM   6253 H  HD2    . LYS   B  2 114 ? 111.912 -15.176 -14.606 1.00 82.75  ?  4366 LYS   C HD2    1 
ATOM   6254 H  HD3    . LYS   B  2 114 ? 113.211 -14.839 -15.457 1.00 82.75  ?  4366 LYS   C HD3    1 
ATOM   6255 H  HE2    . LYS   B  2 114 ? 113.750 -13.137 -14.019 1.00 74.65  ?  4366 LYS   C HE2    1 
ATOM   6256 H  HE3    . LYS   B  2 114 ? 112.406 -13.369 -13.204 1.00 74.65  ?  4366 LYS   C HE3    1 
ATOM   6257 H  HZ1    . LYS   B  2 114 ? 114.166 -14.342 -12.136 1.00 87.04  ?  4366 LYS   C HZ1    1 
ATOM   6258 H  HZ2    . LYS   B  2 114 ? 113.240 -15.382 -12.535 1.00 87.04  ?  4366 LYS   C HZ2    1 
ATOM   6259 H  HZ3    . LYS   B  2 114 ? 114.464 -15.176 -13.282 1.00 87.04  ?  4366 LYS   C HZ3    1 
ATOM   6260 N  N      . ASN   B  2 115 ? 109.039 -14.871 -19.671 1.00 47.35  ?  4367 ASN   C N      1 
ATOM   6261 C  CA     . ASN   B  2 115 ? 108.987 -15.792 -20.798 1.00 52.45  ?  4367 ASN   C CA     1 
ATOM   6262 C  C      . ASN   B  2 115 ? 107.928 -15.356 -21.801 1.00 50.02  ?  4367 ASN   C C      1 
ATOM   6263 O  O      . ASN   B  2 115 ? 107.114 -14.463 -21.549 1.00 54.55  ?  4367 ASN   C O      1 
ATOM   6264 C  CB     . ASN   B  2 115 ? 108.742 -17.233 -20.339 1.00 49.94  ?  4367 ASN   C CB     1 
ATOM   6265 C  CG     . ASN   B  2 115 ? 110.019 -17.908 -19.884 1.00 41.44  ?  4367 ASN   C CG     1 
ATOM   6266 O  OD1    . ASN   B  2 115 ? 110.790 -18.405 -20.695 1.00 51.35  ?  4367 ASN   C OD1    1 
ATOM   6267 N  ND2    . ASN   B  2 115 ? 110.237 -17.952 -18.575 1.00 49.87  ?  4367 ASN   C ND2    1 
ATOM   6268 H  H      . ASN   B  2 115 ? 108.288 -14.734 -19.275 1.00 57.34  ?  4367 ASN   C H      1 
ATOM   6269 H  HA     . ASN   B  2 115 ? 109.841 -15.761 -21.257 1.00 63.46  ?  4367 ASN   C HA     1 
ATOM   6270 H  HB2    . ASN   B  2 115 ? 108.119 -17.229 -19.595 1.00 60.45  ?  4367 ASN   C HB2    1 
ATOM   6271 H  HB3    . ASN   B  2 115 ? 108.374 -17.745 -21.077 1.00 60.45  ?  4367 ASN   C HB3    1 
ATOM   6272 H  HD21   . ASN   B  2 115 ? 110.949 -18.325 -18.270 1.00 60.36  ?  4367 ASN   C HD21   1 
ATOM   6273 H  HD22   . ASN   B  2 115 ? 109.666 -17.607 -18.033 1.00 60.36  ?  4367 ASN   C HD22   1 
ATOM   6274 N  N      . THR   B  2 116 ? 107.945 -16.017 -22.956 1.00 51.43  ?  4368 THR   C N      1 
ATOM   6275 C  CA     . THR   B  2 116 ? 107.215 -15.539 -24.117 1.00 53.09  ?  4368 THR   C CA     1 
ATOM   6276 C  C      . THR   B  2 116 ? 106.516 -16.687 -24.824 1.00 53.74  ?  4368 THR   C C      1 
ATOM   6277 O  O      . THR   B  2 116 ? 107.099 -17.758 -25.025 1.00 57.47  ?  4368 THR   C O      1 
ATOM   6278 C  CB     . THR   B  2 116 ? 108.160 -14.833 -25.099 1.00 58.70  ?  4368 THR   C CB     1 
ATOM   6279 O  OG1    . THR   B  2 116 ? 108.830 -13.755 -24.431 1.00 63.85  ?  4368 THR   C OG1    1 
ATOM   6280 C  CG2    . THR   B  2 116 ? 107.397 -14.292 -26.275 1.00 58.13  ?  4368 THR   C CG2    1 
ATOM   6281 H  H      . THR   B  2 116 ? 108.376 -16.749 -23.088 1.00 62.24  ?  4368 THR   C H      1 
ATOM   6282 H  HA     . THR   B  2 116 ? 106.528 -14.920 -23.825 1.00 64.23  ?  4368 THR   C HA     1 
ATOM   6283 H  HB     . THR   B  2 116 ? 108.816 -15.467 -25.428 1.00 70.96  ?  4368 THR   C HB     1 
ATOM   6284 H  HG1    . THR   B  2 116 ? 109.347 -13.363 -24.964 1.00 77.14  ?  4368 THR   C HG1    1 
ATOM   6285 H  HG21   . THR   B  2 116 ? 107.944 -13.654 -26.761 1.00 70.28  ?  4368 THR   C HG21   1 
ATOM   6286 H  HG22   . THR   B  2 116 ? 107.152 -15.016 -26.873 1.00 70.28  ?  4368 THR   C HG22   1 
ATOM   6287 H  HG23   . THR   B  2 116 ? 106.590 -13.848 -25.971 1.00 70.28  ?  4368 THR   C HG23   1 
ATOM   6288 N  N      . VAL   B  2 117 ? 105.269 -16.435 -25.213 1.00 51.74  ?  4369 VAL   C N      1 
ATOM   6289 C  CA     . VAL   B  2 117 ? 104.432 -17.409 -25.898 1.00 56.24  ?  4369 VAL   C CA     1 
ATOM   6290 C  C      . VAL   B  2 117 ? 104.657 -17.276 -27.396 1.00 57.56  ?  4369 VAL   C C      1 
ATOM   6291 O  O      . VAL   B  2 117 ? 104.597 -16.169 -27.945 1.00 57.60  ?  4369 VAL   C O      1 
ATOM   6292 C  CB     . VAL   B  2 117 ? 102.949 -17.187 -25.551 1.00 52.69  ?  4369 VAL   C CB     1 
ATOM   6293 C  CG1    . VAL   B  2 117 ? 102.104 -18.303 -26.113 1.00 52.38  ?  4369 VAL   C CG1    1 
ATOM   6294 C  CG2    . VAL   B  2 117 ? 102.766 -17.040 -24.042 1.00 48.30  ?  4369 VAL   C CG2    1 
ATOM   6295 H  H      . VAL   B  2 117 ? 104.874 -15.682 -25.085 1.00 62.62  ?  4369 VAL   C H      1 
ATOM   6296 H  HA     . VAL   B  2 117 ? 104.688 -18.304 -25.624 1.00 68.01  ?  4369 VAL   C HA     1 
ATOM   6297 H  HB     . VAL   B  2 117 ? 102.646 -16.360 -25.957 1.00 63.75  ?  4369 VAL   C HB     1 
ATOM   6298 H  HG11   . VAL   B  2 117 ? 101.192 -18.197 -25.801 1.00 63.38  ?  4369 VAL   C HG11   1 
ATOM   6299 H  HG12   . VAL   B  2 117 ? 102.129 -18.261 -27.082 1.00 63.38  ?  4369 VAL   C HG12   1 
ATOM   6300 H  HG13   . VAL   B  2 117 ? 102.461 -19.153 -25.810 1.00 63.38  ?  4369 VAL   C HG13   1 
ATOM   6301 H  HG21   . VAL   B  2 117 ? 101.818 -17.029 -23.839 1.00 58.48  ?  4369 VAL   C HG21   1 
ATOM   6302 H  HG22   . VAL   B  2 117 ? 103.191 -17.790 -23.598 1.00 58.48  ?  4369 VAL   C HG22   1 
ATOM   6303 H  HG23   . VAL   B  2 117 ? 103.176 -16.210 -23.753 1.00 58.48  ?  4369 VAL   C HG23   1 
ATOM   6304 N  N      . CYS   B  2 118 ? 104.917 -18.397 -28.060 1.00 60.87  ?  4370 CYS   C N      1 
ATOM   6305 C  CA     . CYS   B  2 118 ? 104.993 -18.387 -29.516 1.00 62.42  ?  4370 CYS   C CA     1 
ATOM   6306 C  C      . CYS   B  2 118 ? 103.638 -18.041 -30.107 1.00 60.02  ?  4370 CYS   C C      1 
ATOM   6307 O  O      . CYS   B  2 118 ? 102.658 -18.760 -29.897 1.00 62.14  ?  4370 CYS   C O      1 
ATOM   6308 C  CB     . CYS   B  2 118 ? 105.443 -19.742 -30.048 1.00 68.50  ?  4370 CYS   C CB     1 
ATOM   6309 S  SG     . CYS   B  2 118 ? 105.249 -19.888 -31.852 1.00 71.70  ?  4370 CYS   C SG     1 
ATOM   6310 H  H      . CYS   B  2 118 ? 105.052 -19.165 -27.697 1.00 73.57  ?  4370 CYS   C H      1 
ATOM   6311 H  HA     . CYS   B  2 118 ? 105.647 -17.722 -29.784 1.00 75.42  ?  4370 CYS   C HA     1 
ATOM   6312 H  HB2    . CYS   B  2 118 ? 106.380 -19.870 -29.834 1.00 82.73  ?  4370 CYS   C HB2    1 
ATOM   6313 H  HB3    . CYS   B  2 118 ? 104.910 -20.438 -29.631 1.00 82.73  ?  4370 CYS   C HB3    1 
ATOM   6314 N  N      . THR   B  2 119 ? 103.596 -16.959 -30.879 1.00 74.50  ?  4371 THR   C N      1 
ATOM   6315 C  CA     . THR   B  2 119 ? 102.364 -16.498 -31.504 1.00 71.66  ?  4371 THR   C CA     1 
ATOM   6316 C  C      . THR   B  2 119 ? 101.806 -17.478 -32.523 1.00 68.92  ?  4371 THR   C C      1 
ATOM   6317 O  O      . THR   B  2 119 ? 100.673 -17.280 -32.983 1.00 69.33  ?  4371 THR   C O      1 
ATOM   6318 C  CB     . THR   B  2 119 ? 102.629 -15.143 -32.145 1.00 72.40  ?  4371 THR   C CB     1 
ATOM   6319 O  OG1    . THR   B  2 119 ? 103.991 -15.097 -32.607 1.00 76.87  ?  4371 THR   C OG1    1 
ATOM   6320 C  CG2    . THR   B  2 119 ? 102.431 -14.030 -31.133 1.00 66.15  ?  4371 THR   C CG2    1 
ATOM   6321 H  H      . THR   B  2 119 ? 104.279 -16.467 -31.058 1.00 89.92  ?  4371 THR   C H      1 
ATOM   6322 H  HA     . THR   B  2 119 ? 101.675 -16.390 -30.830 1.00 86.51  ?  4371 THR   C HA     1 
ATOM   6323 H  HB     . THR   B  2 119 ? 102.016 -15.009 -32.885 1.00 87.40  ?  4371 THR   C HB     1 
ATOM   6324 H  HG1    . THR   B  2 119 ? 104.173 -14.328 -32.892 1.00 92.77  ?  4371 THR   C HG1    1 
ATOM   6325 H  HG21   . THR   B  2 119 ? 102.648 -13.174 -31.535 1.00 79.90  ?  4371 THR   C HG21   1 
ATOM   6326 H  HG22   . THR   B  2 119 ? 101.509 -14.014 -30.834 1.00 79.90  ?  4371 THR   C HG22   1 
ATOM   6327 H  HG23   . THR   B  2 119 ? 103.008 -14.173 -30.366 1.00 79.90  ?  4371 THR   C HG23   1 
ATOM   6328 N  N      . VAL   B  2 120 ? 102.536 -18.542 -32.854 1.00 67.30  ?  4372 VAL   C N      1 
ATOM   6329 C  CA     . VAL   B  2 120 ? 102.086 -19.463 -33.891 1.00 58.73  ?  4372 VAL   C CA     1 
ATOM   6330 C  C      . VAL   B  2 120 ? 101.516 -20.732 -33.274 1.00 58.07  ?  4372 VAL   C C      1 
ATOM   6331 O  O      . VAL   B  2 120 ? 100.374 -21.109 -33.558 1.00 62.51  ?  4372 VAL   C O      1 
ATOM   6332 C  CB     . VAL   B  2 120 ? 103.222 -19.804 -34.867 1.00 69.49  ?  4372 VAL   C CB     1 
ATOM   6333 C  CG1    . VAL   B  2 120 ? 102.759 -20.846 -35.872 1.00 64.79  ?  4372 VAL   C CG1    1 
ATOM   6334 C  CG2    . VAL   B  2 120 ? 103.709 -18.553 -35.577 1.00 64.40  ?  4372 VAL   C CG2    1 
ATOM   6335 H  H      . VAL   B  2 120 ? 103.290 -18.749 -32.494 1.00 81.29  ?  4372 VAL   C H      1 
ATOM   6336 H  HA     . VAL   B  2 120 ? 101.371 -19.026 -34.379 1.00 71.00  ?  4372 VAL   C HA     1 
ATOM   6337 H  HB     . VAL   B  2 120 ? 103.967 -20.175 -34.367 1.00 83.91  ?  4372 VAL   C HB     1 
ATOM   6338 H  HG11   . VAL   B  2 120 ? 103.346 -20.823 -36.644 1.00 78.27  ?  4372 VAL   C HG11   1 
ATOM   6339 H  HG12   . VAL   B  2 120 ? 102.793 -21.722 -35.457 1.00 78.27  ?  4372 VAL   C HG12   1 
ATOM   6340 H  HG13   . VAL   B  2 120 ? 101.850 -20.643 -36.141 1.00 78.27  ?  4372 VAL   C HG13   1 
ATOM   6341 H  HG21   . VAL   B  2 120 ? 104.355 -18.806 -36.256 1.00 77.80  ?  4372 VAL   C HG21   1 
ATOM   6342 H  HG22   . VAL   B  2 120 ? 102.952 -18.109 -35.990 1.00 77.80  ?  4372 VAL   C HG22   1 
ATOM   6343 H  HG23   . VAL   B  2 120 ? 104.125 -17.963 -34.929 1.00 77.80  ?  4372 VAL   C HG23   1 
ATOM   6344 N  N      . CYS   B  2 121 ? 102.302 -21.413 -32.443 1.00 59.40  ?  4373 CYS   C N      1 
ATOM   6345 C  CA     . CYS   B  2 121 ? 101.894 -22.703 -31.916 1.00 61.49  ?  4373 CYS   C CA     1 
ATOM   6346 C  C      . CYS   B  2 121 ? 101.292 -22.635 -30.520 1.00 64.37  ?  4373 CYS   C C      1 
ATOM   6347 O  O      . CYS   B  2 121 ? 100.710 -23.629 -30.077 1.00 62.78  ?  4373 CYS   C O      1 
ATOM   6348 C  CB     . CYS   B  2 121 ? 103.086 -23.672 -31.924 1.00 56.80  ?  4373 CYS   C CB     1 
ATOM   6349 S  SG     . CYS   B  2 121 ? 104.381 -23.330 -30.687 1.00 58.00  ?  4373 CYS   C SG     1 
ATOM   6350 H  H      . CYS   B  2 121 ? 103.073 -21.145 -32.173 1.00 71.81  ?  4373 CYS   C H      1 
ATOM   6351 H  HA     . CYS   B  2 121 ? 101.210 -23.071 -32.496 1.00 74.31  ?  4373 CYS   C HA     1 
ATOM   6352 H  HB2    . CYS   B  2 121 ? 102.753 -24.567 -31.755 1.00 68.68  ?  4373 CYS   C HB2    1 
ATOM   6353 H  HB3    . CYS   B  2 121 ? 103.504 -23.633 -32.799 1.00 68.68  ?  4373 CYS   C HB3    1 
ATOM   6354 N  N      . GLY   B  2 122 ? 101.382 -21.497 -29.836 1.00 59.11  ?  4374 GLY   C N      1 
ATOM   6355 C  CA     . GLY   B  2 122 ? 100.769 -21.349 -28.539 1.00 61.82  ?  4374 GLY   C CA     1 
ATOM   6356 C  C      . GLY   B  2 122 ? 101.576 -21.889 -27.383 1.00 53.24  ?  4374 GLY   C C      1 
ATOM   6357 O  O      . GLY   B  2 122 ? 101.085 -21.873 -26.249 1.00 56.56  ?  4374 GLY   C O      1 
ATOM   6358 H  H      . GLY   B  2 122 ? 101.798 -20.796 -30.112 1.00 71.46  ?  4374 GLY   C H      1 
ATOM   6359 H  HA2    . GLY   B  2 122 ? 100.615 -20.405 -28.375 1.00 74.71  ?  4374 GLY   C HA2    1 
ATOM   6360 H  HA3    . GLY   B  2 122 ? 99.917  -21.812 -28.545 1.00 74.71  ?  4374 GLY   C HA3    1 
ATOM   6361 N  N      . MET   B  2 123 ? 102.787 -22.368 -27.628 1.00 53.31  ?  4375 MET   C N      1 
ATOM   6362 C  CA     . MET   B  2 123 ? 103.639 -22.900 -26.580 1.00 48.08  ?  4375 MET   C CA     1 
ATOM   6363 C  C      . MET   B  2 123 ? 104.577 -21.811 -26.074 1.00 53.19  ?  4375 MET   C C      1 
ATOM   6364 O  O      . MET   B  2 123 ? 104.770 -20.775 -26.718 1.00 59.67  ?  4375 MET   C O      1 
ATOM   6365 C  CB     . MET   B  2 123 ? 104.445 -24.099 -27.089 1.00 54.69  ?  4375 MET   C CB     1 
ATOM   6366 C  CG     . MET   B  2 123 ? 103.654 -25.096 -27.889 1.00 58.23  ?  4375 MET   C CG     1 
ATOM   6367 S  SD     . MET   B  2 123 ? 102.639 -26.185 -26.888 1.00 57.81  ?  4375 MET   C SD     1 
ATOM   6368 C  CE     . MET   B  2 123 ? 103.894 -27.061 -25.987 1.00 53.57  ?  4375 MET   C CE     1 
ATOM   6369 H  H      . MET   B  2 123 ? 103.144 -22.395 -28.410 1.00 64.50  ?  4375 MET   C H      1 
ATOM   6370 H  HA     . MET   B  2 123 ? 103.088 -23.215 -25.846 1.00 58.22  ?  4375 MET   C HA     1 
ATOM   6371 H  HB2    . MET   B  2 123 ? 105.160 -23.770 -27.657 1.00 66.15  ?  4375 MET   C HB2    1 
ATOM   6372 H  HB3    . MET   B  2 123 ? 104.818 -24.566 -26.325 1.00 66.15  ?  4375 MET   C HB3    1 
ATOM   6373 H  HG2    . MET   B  2 123 ? 103.065 -24.616 -28.492 1.00 70.40  ?  4375 MET   C HG2    1 
ATOM   6374 H  HG3    . MET   B  2 123 ? 104.269 -25.649 -28.395 1.00 70.40  ?  4375 MET   C HG3    1 
ATOM   6375 H  HE1    . MET   B  2 123 ? 103.494 -27.834 -25.560 1.00 64.81  ?  4375 MET   C HE1    1 
ATOM   6376 H  HE2    . MET   B  2 123 ? 104.585 -27.345 -26.605 1.00 64.81  ?  4375 MET   C HE2    1 
ATOM   6377 H  HE3    . MET   B  2 123 ? 104.272 -26.471 -25.317 1.00 64.81  ?  4375 MET   C HE3    1 
ATOM   6378 N  N      . TRP   B  2 124 ? 105.153 -22.049 -24.897 1.00 57.58  ?  4376 TRP   C N      1 
ATOM   6379 C  CA     . TRP   B  2 124 ? 106.183 -21.158 -24.389 1.00 50.87  ?  4376 TRP   C CA     1 
ATOM   6380 C  C      . TRP   B  2 124 ? 107.431 -21.299 -25.253 1.00 54.97  ?  4376 TRP   C C      1 
ATOM   6381 O  O      . TRP   B  2 124 ? 107.880 -22.416 -25.530 1.00 50.92  ?  4376 TRP   C O      1 
ATOM   6382 C  CB     . TRP   B  2 124 ? 106.521 -21.484 -22.936 1.00 58.09  ?  4376 TRP   C CB     1 
ATOM   6383 C  CG     . TRP   B  2 124 ? 105.493 -21.082 -21.925 1.00 53.80  ?  4376 TRP   C CG     1 
ATOM   6384 C  CD1    . TRP   B  2 124 ? 104.721 -21.922 -21.171 1.00 51.61  ?  4376 TRP   C CD1    1 
ATOM   6385 C  CD2    . TRP   B  2 124 ? 105.144 -19.748 -21.520 1.00 56.36  ?  4376 TRP   C CD2    1 
ATOM   6386 N  NE1    . TRP   B  2 124 ? 103.909 -21.195 -20.336 1.00 52.35  ?  4376 TRP   C NE1    1 
ATOM   6387 C  CE2    . TRP   B  2 124 ? 104.150 -19.863 -20.530 1.00 51.06  ?  4376 TRP   C CE2    1 
ATOM   6388 C  CE3    . TRP   B  2 124 ? 105.565 -18.468 -21.903 1.00 54.48  ?  4376 TRP   C CE3    1 
ATOM   6389 C  CZ2    . TRP   B  2 124 ? 103.576 -18.756 -19.921 1.00 46.41  ?  4376 TRP   C CZ2    1 
ATOM   6390 C  CZ3    . TRP   B  2 124 ? 104.989 -17.371 -21.292 1.00 55.25  ?  4376 TRP   C CZ3    1 
ATOM   6391 C  CH2    . TRP   B  2 124 ? 104.011 -17.523 -20.313 1.00 52.17  ?  4376 TRP   C CH2    1 
ATOM   6392 H  H      . TRP   B  2 124 ? 104.965 -22.713 -24.383 1.00 69.62  ?  4376 TRP   C H      1 
ATOM   6393 H  HA     . TRP   B  2 124 ? 105.863 -20.243 -24.419 1.00 61.56  ?  4376 TRP   C HA     1 
ATOM   6394 H  HB2    . TRP   B  2 124 ? 106.640 -22.444 -22.859 1.00 70.23  ?  4376 TRP   C HB2    1 
ATOM   6395 H  HB3    . TRP   B  2 124 ? 107.345 -21.028 -22.705 1.00 70.23  ?  4376 TRP   C HB3    1 
ATOM   6396 H  HD1    . TRP   B  2 124 ? 104.742 -22.850 -21.218 1.00 62.46  ?  4376 TRP   C HD1    1 
ATOM   6397 H  HE1    . TRP   B  2 124 ? 103.341 -21.524 -19.780 1.00 63.34  ?  4376 TRP   C HE1    1 
ATOM   6398 H  HE3    . TRP   B  2 124 ? 106.219 -18.359 -22.556 1.00 65.89  ?  4376 TRP   C HE3    1 
ATOM   6399 H  HZ2    . TRP   B  2 124 ? 102.920 -18.851 -19.269 1.00 56.21  ?  4376 TRP   C HZ2    1 
ATOM   6400 H  HZ3    . TRP   B  2 124 ? 105.260 -16.517 -21.538 1.00 66.82  ?  4376 TRP   C HZ3    1 
ATOM   6401 H  HH2    . TRP   B  2 124 ? 103.644 -16.766 -19.917 1.00 63.12  ?  4376 TRP   C HH2    1 
ATOM   6402 N  N      . LYS   B  2 125 ? 107.975 -20.170 -25.709 1.00 57.80  ?  4377 LYS   C N      1 
ATOM   6403 C  CA     . LYS   B  2 125 ? 109.266 -20.191 -26.394 1.00 57.91  ?  4377 LYS   C CA     1 
ATOM   6404 C  C      . LYS   B  2 125 ? 110.317 -20.823 -25.485 1.00 53.18  ?  4377 LYS   C C      1 
ATOM   6405 O  O      . LYS   B  2 125 ? 110.535 -20.362 -24.361 1.00 61.78  ?  4377 LYS   C O      1 
ATOM   6406 C  CB     . LYS   B  2 125 ? 109.680 -18.772 -26.791 1.00 56.38  ?  4377 LYS   C CB     1 
ATOM   6407 C  CG     . LYS   B  2 125 ? 109.027 -18.169 -28.036 1.00 64.36  ?  4377 LYS   C CG     1 
ATOM   6408 C  CD     . LYS   B  2 125 ? 109.405 -18.889 -29.334 1.00 78.89  ?  4377 LYS   C CD     1 
ATOM   6409 C  CE     . LYS   B  2 125 ? 108.440 -18.539 -30.479 1.00 88.48  ?  4377 LYS   C CE     1 
ATOM   6410 N  NZ     . LYS   B  2 125 ? 109.104 -18.411 -31.826 1.00 94.99  ?  4377 LYS   C NZ     1 
ATOM   6411 H  H      . LYS   B  2 125 ? 107.622 -19.389 -25.634 1.00 69.89  ?  4377 LYS   C H      1 
ATOM   6412 H  HA     . LYS   B  2 125 ? 109.195 -20.717 -27.206 1.00 70.02  ?  4377 LYS   C HA     1 
ATOM   6413 H  HB2    . LYS   B  2 125 ? 109.469 -18.182 -26.050 1.00 68.18  ?  4377 LYS   C HB2    1 
ATOM   6414 H  HB3    . LYS   B  2 125 ? 110.637 -18.775 -26.950 1.00 68.18  ?  4377 LYS   C HB3    1 
ATOM   6415 H  HG2    . LYS   B  2 125 ? 108.063 -18.218 -27.939 1.00 77.76  ?  4377 LYS   C HG2    1 
ATOM   6416 H  HG3    . LYS   B  2 125 ? 109.305 -17.243 -28.118 1.00 77.76  ?  4377 LYS   C HG3    1 
ATOM   6417 H  HD2    . LYS   B  2 125 ? 110.300 -18.624 -29.599 1.00 95.19  ?  4377 LYS   C HD2    1 
ATOM   6418 H  HD3    . LYS   B  2 125 ? 109.371 -19.847 -29.190 1.00 95.19  ?  4377 LYS   C HD3    1 
ATOM   6419 H  HE2    . LYS   B  2 125 ? 107.772 -19.239 -30.547 1.00 106.69 ?  4377 LYS   C HE2    1 
ATOM   6420 H  HE3    . LYS   B  2 125 ? 108.014 -17.691 -30.279 1.00 106.69 ?  4377 LYS   C HE3    1 
ATOM   6421 H  HZ1    . LYS   B  2 125 ? 108.500 -18.197 -32.444 1.00 114.51 ?  4377 LYS   C HZ1    1 
ATOM   6422 H  HZ2    . LYS   B  2 125 ? 109.727 -17.775 -31.799 1.00 114.51 ?  4377 LYS   C HZ2    1 
ATOM   6423 H  HZ3    . LYS   B  2 125 ? 109.487 -19.181 -32.052 1.00 114.51 ?  4377 LYS   C HZ3    1 
ATOM   6424 N  N      . GLY   B  2 126 ? 110.960 -21.887 -25.964 1.00 57.46  ?  4378 GLY   C N      1 
ATOM   6425 C  CA     . GLY   B  2 126 ? 111.986 -22.566 -25.197 1.00 60.29  ?  4378 GLY   C CA     1 
ATOM   6426 C  C      . GLY   B  2 126 ? 111.474 -23.581 -24.208 1.00 61.68  ?  4378 GLY   C C      1 
ATOM   6427 O  O      . GLY   B  2 126 ? 112.284 -24.219 -23.525 1.00 59.36  ?  4378 GLY   C O      1 
ATOM   6428 H  H      . GLY   B  2 126 ? 110.815 -22.232 -26.738 1.00 69.47  ?  4378 GLY   C H      1 
ATOM   6429 H  HA2    . GLY   B  2 126 ? 112.579 -23.026 -25.812 1.00 72.87  ?  4378 GLY   C HA2    1 
ATOM   6430 H  HA3    . GLY   B  2 126 ? 112.495 -21.904 -24.704 1.00 72.87  ?  4378 GLY   C HA3    1 
ATOM   6431 N  N      . TYR   B  2 127 ? 110.162 -23.750 -24.106 1.00 65.55  ?  4379 TYR   C N      1 
ATOM   6432 C  CA     . TYR   B  2 127 ? 109.555 -24.701 -23.189 1.00 57.55  ?  4379 TYR   C CA     1 
ATOM   6433 C  C      . TYR   B  2 127 ? 108.379 -25.371 -23.897 1.00 59.65  ?  4379 TYR   C C      1 
ATOM   6434 O  O      . TYR   B  2 127 ? 107.282 -25.504 -23.351 1.00 60.48  ?  4379 TYR   C O      1 
ATOM   6435 C  CB     . TYR   B  2 127 ? 109.119 -24.016 -21.889 1.00 54.19  ?  4379 TYR   C CB     1 
ATOM   6436 C  CG     . TYR   B  2 127 ? 110.236 -23.429 -21.017 1.00 47.13  ?  4379 TYR   C CG     1 
ATOM   6437 C  CD1    . TYR   B  2 127 ? 110.826 -24.184 -20.005 1.00 51.62  ?  4379 TYR   C CD1    1 
ATOM   6438 C  CD2    . TYR   B  2 127 ? 110.660 -22.115 -21.163 1.00 51.37  ?  4379 TYR   C CD2    1 
ATOM   6439 C  CE1    . TYR   B  2 127 ? 111.818 -23.659 -19.193 1.00 55.46  ?  4379 TYR   C CE1    1 
ATOM   6440 C  CE2    . TYR   B  2 127 ? 111.663 -21.580 -20.348 1.00 55.85  ?  4379 TYR   C CE2    1 
ATOM   6441 C  CZ     . TYR   B  2 127 ? 112.226 -22.363 -19.363 1.00 58.35  ?  4379 TYR   C CZ     1 
ATOM   6442 O  OH     . TYR   B  2 127 ? 113.218 -21.872 -18.540 1.00 55.43  ?  4379 TYR   C OH     1 
ATOM   6443 H  H      . TYR   B  2 127 ? 109.587 -23.313 -24.572 1.00 79.18  ?  4379 TYR   C H      1 
ATOM   6444 H  HA     . TYR   B  2 127 ? 110.203 -25.383 -22.951 1.00 69.58  ?  4379 TYR   C HA     1 
ATOM   6445 H  HB2    . TYR   B  2 127 ? 108.524 -23.286 -22.119 1.00 65.55  ?  4379 TYR   C HB2    1 
ATOM   6446 H  HB3    . TYR   B  2 127 ? 108.648 -24.669 -21.347 1.00 65.55  ?  4379 TYR   C HB3    1 
ATOM   6447 H  HD1    . TYR   B  2 127 ? 110.548 -25.061 -19.872 1.00 62.47  ?  4379 TYR   C HD1    1 
ATOM   6448 H  HD2    . TYR   B  2 127 ? 110.270 -21.579 -21.816 1.00 62.16  ?  4379 TYR   C HD2    1 
ATOM   6449 H  HE1    . TYR   B  2 127 ? 112.206 -24.186 -18.533 1.00 67.07  ?  4379 TYR   C HE1    1 
ATOM   6450 H  HE2    . TYR   B  2 127 ? 111.947 -20.703 -20.469 1.00 67.55  ?  4379 TYR   C HE2    1 
ATOM   6451 H  HH     . TYR   B  2 127 ? 113.483 -22.474 -18.018 1.00 67.03  ?  4379 TYR   C HH     1 
ATOM   6452 N  N      . GLY   B  2 128 ? 108.602 -25.781 -25.147 1.00 61.69  ?  4380 GLY   C N      1 
ATOM   6453 C  CA     . GLY   B  2 128 ? 107.569 -26.442 -25.916 1.00 55.90  ?  4380 GLY   C CA     1 
ATOM   6454 C  C      . GLY   B  2 128 ? 107.477 -26.000 -27.362 1.00 58.62  ?  4380 GLY   C C      1 
ATOM   6455 O  O      . GLY   B  2 128 ? 107.028 -26.765 -28.224 1.00 63.80  ?  4380 GLY   C O      1 
ATOM   6456 H  H      . GLY   B  2 128 ? 109.346 -25.683 -25.567 1.00 74.55  ?  4380 GLY   C H      1 
ATOM   6457 H  HA2    . GLY   B  2 128 ? 107.738 -27.397 -25.909 1.00 67.60  ?  4380 GLY   C HA2    1 
ATOM   6458 H  HA3    . GLY   B  2 128 ? 106.710 -26.270 -25.499 1.00 67.60  ?  4380 GLY   C HA3    1 
ATOM   6459 N  N      . CYS   B  2 129 ? 107.893 -24.771 -27.650 1.00 61.86  ?  4381 CYS   C N      1 
ATOM   6460 C  CA     . CYS   B  2 129 ? 107.820 -24.272 -29.018 1.00 68.06  ?  4381 CYS   C CA     1 
ATOM   6461 C  C      . CYS   B  2 129 ? 108.917 -24.915 -29.861 1.00 72.53  ?  4381 CYS   C C      1 
ATOM   6462 O  O      . CYS   B  2 129 ? 110.110 -24.692 -29.620 1.00 68.12  ?  4381 CYS   C O      1 
ATOM   6463 C  CB     . CYS   B  2 129 ? 107.944 -22.754 -29.057 1.00 63.15  ?  4381 CYS   C CB     1 
ATOM   6464 S  SG     . CYS   B  2 129 ? 108.056 -22.155 -30.765 1.00 67.08  ?  4381 CYS   C SG     1 
ATOM   6465 H  H      . CYS   B  2 129 ? 108.217 -24.215 -27.080 1.00 74.76  ?  4381 CYS   C H      1 
ATOM   6466 H  HA     . CYS   B  2 129 ? 106.956 -24.508 -29.390 1.00 82.19  ?  4381 CYS   C HA     1 
ATOM   6467 H  HB2    . CYS   B  2 129 ? 107.163 -22.356 -28.641 1.00 76.30  ?  4381 CYS   C HB2    1 
ATOM   6468 H  HB3    . CYS   B  2 129 ? 108.746 -22.485 -28.582 1.00 76.30  ?  4381 CYS   C HB3    1 
ATOM   6469 N  N      . SER   B  2 130 ? 108.510 -25.709 -30.853 1.00 75.83  ?  4382 SER   C N      1 
ATOM   6470 C  CA     . SER   B  2 130 ? 109.427 -26.347 -31.792 1.00 82.57  ?  4382 SER   C CA     1 
ATOM   6471 C  C      . SER   B  2 130 ? 109.282 -25.786 -33.203 1.00 89.45  ?  4382 SER   C C      1 
ATOM   6472 O  O      . SER   B  2 130 ? 109.668 -26.448 -34.172 1.00 86.72  ?  4382 SER   C O      1 
ATOM   6473 C  CB     . SER   B  2 130 ? 109.189 -27.855 -31.814 1.00 76.95  ?  4382 SER   C CB     1 
ATOM   6474 O  OG     . SER   B  2 130 ? 107.859 -28.144 -32.220 1.00 79.21  ?  4382 SER   C OG     1 
ATOM   6475 H  H      . SER   B  2 130 ? 107.685 -25.896 -31.005 1.00 91.51  ?  4382 SER   C H      1 
ATOM   6476 H  HA     . SER   B  2 130 ? 110.335 -26.183 -31.493 1.00 99.60  ?  4382 SER   C HA     1 
ATOM   6477 H  HB2    . SER   B  2 130 ? 109.807 -28.265 -32.438 1.00 92.86  ?  4382 SER   C HB2    1 
ATOM   6478 H  HB3    . SER   B  2 130 ? 109.333 -28.212 -30.923 1.00 92.86  ?  4382 SER   C HB3    1 
ATOM   6479 H  HG     . SER   B  2 130 ? 107.743 -28.975 -32.255 1.00 95.57  ?  4382 SER   C HG     1 
ATOM   6480 N  N      . CYS   B  2 131 ? 108.698 -24.594 -33.338 1.00 88.66  ?  4383 CYS   C N      1 
ATOM   6481 C  CA     . CYS   B  2 131 ? 108.535 -23.989 -34.650 1.00 90.51  ?  4383 CYS   C CA     1 
ATOM   6482 C  C      . CYS   B  2 131 ? 109.888 -23.762 -35.315 1.00 96.04  ?  4383 CYS   C C      1 
ATOM   6483 O  O      . CYS   B  2 131 ? 110.003 -23.847 -36.543 1.00 99.56  ?  4383 CYS   C O      1 
ATOM   6484 C  CB     . CYS   B  2 131 ? 107.783 -22.665 -34.494 1.00 78.44  ?  4383 CYS   C CB     1 
ATOM   6485 S  SG     . CYS   B  2 131 ? 106.029 -22.826 -34.030 1.00 81.86  ?  4383 CYS   C SG     1 
ATOM   6486 H  H      . CYS   B  2 131 ? 108.391 -24.122 -32.688 1.00 106.91 ?  4383 CYS   C H      1 
ATOM   6487 H  HA     . CYS   B  2 131 ? 108.015 -24.571 -35.225 1.00 109.13 ?  4383 CYS   C HA     1 
ATOM   6488 H  HB2    . CYS   B  2 131 ? 108.221 -22.144 -33.802 1.00 94.65  ?  4383 CYS   C HB2    1 
ATOM   6489 H  HB3    . CYS   B  2 131 ? 107.818 -22.191 -35.339 1.00 94.65  ?  4383 CYS   C HB3    1 
ATOM   6490 N  N      . ASP   B  2 132 ? 110.928 -23.529 -34.516 1.00 95.55  ?  4384 ASP   C N      1 
ATOM   6491 C  CA     . ASP   B  2 132 ? 112.234 -23.089 -35.012 1.00 95.06  ?  4384 ASP   C CA     1 
ATOM   6492 C  C      . ASP   B  2 132 ? 113.212 -24.267 -35.094 1.00 100.90 ?  4384 ASP   C C      1 
ATOM   6493 O  O      . ASP   B  2 132 ? 114.288 -24.253 -34.492 1.00 97.51  ?  4384 ASP   C O      1 
ATOM   6494 C  CB     . ASP   B  2 132 ? 112.786 -21.990 -34.097 1.00 96.99  ?  4384 ASP   C CB     1 
ATOM   6495 C  CG     . ASP   B  2 132 ? 112.155 -20.625 -34.340 1.00 110.61 ?  4384 ASP   C CG     1 
ATOM   6496 O  OD1    . ASP   B  2 132 ? 112.028 -19.852 -33.371 1.00 112.62 ?  4384 ASP   C OD1    1 
ATOM   6497 O  OD2    . ASP   B  2 132 ? 111.832 -20.296 -35.495 1.00 102.41 ?  4384 ASP   C OD2    1 
ATOM   6498 H  H      . ASP   B  2 132 ? 110.902 -23.620 -33.661 1.00 115.18 ?  4384 ASP   C H      1 
ATOM   6499 H  HA     . ASP   B  2 132 ? 112.122 -22.730 -35.906 1.00 114.59 ?  4384 ASP   C HA     1 
ATOM   6500 H  HB2    . ASP   B  2 132 ? 112.617 -22.236 -33.174 1.00 116.91 ?  4384 ASP   C HB2    1 
ATOM   6501 H  HB3    . ASP   B  2 132 ? 113.741 -21.907 -34.248 1.00 116.91 ?  4384 ASP   C HB3    1 
ATOM   6502 N  N      . GLN   B  2 133 ? 112.853 -25.293 -35.871 1.00 106.44 ?  4385 GLN   C N      1 
ATOM   6503 C  CA     . GLN   B  2 133 ? 113.730 -26.468 -35.991 1.00 105.14 ?  4385 GLN   C CA     1 
ATOM   6504 C  C      . GLN   B  2 133 ? 113.750 -27.154 -37.354 1.00 102.45 ?  4385 GLN   C C      1 
ATOM   6505 O  O      . GLN   B  2 133 ? 112.755 -27.204 -38.061 1.00 97.42  ?  4385 GLN   C O      1 
ATOM   6506 C  CB     . GLN   B  2 133 ? 113.341 -27.509 -34.922 1.00 98.54  ?  4385 GLN   C CB     1 
ATOM   6507 C  CG     . GLN   B  2 133 ? 112.405 -28.623 -35.411 1.00 106.82 ?  4385 GLN   C CG     1 
ATOM   6508 C  CD     . GLN   B  2 133 ? 111.717 -29.402 -34.284 1.00 93.76  ?  4385 GLN   C CD     1 
ATOM   6509 O  OE1    . GLN   B  2 133 ? 112.135 -29.363 -33.136 1.00 82.61  ?  4385 GLN   C OE1    1 
ATOM   6510 N  NE2    . GLN   B  2 133 ? 110.659 -30.117 -34.629 1.00 84.02  ?  4385 GLN   C NE2    1 
ATOM   6511 H  H      . GLN   B  2 133 ? 112.126 -25.334 -36.328 1.00 128.25 ?  4385 GLN   C H      1 
ATOM   6512 H  HA     . GLN   B  2 133 ? 114.632 -26.136 -35.862 1.00 126.68 ?  4385 GLN   C HA     1 
ATOM   6513 H  HB2    . GLN   B  2 133 ? 114.151 -27.931 -34.596 1.00 118.77 ?  4385 GLN   C HB2    1 
ATOM   6514 H  HB3    . GLN   B  2 133 ? 112.892 -27.050 -34.195 1.00 118.77 ?  4385 GLN   C HB3    1 
ATOM   6515 H  HG2    . GLN   B  2 133 ? 111.711 -28.227 -35.961 1.00 128.70 ?  4385 GLN   C HG2    1 
ATOM   6516 H  HG3    . GLN   B  2 133 ? 112.922 -29.256 -35.934 1.00 128.70 ?  4385 GLN   C HG3    1 
ATOM   6517 H  HE21   . GLN   B  2 133 ? 110.395 -30.126 -35.447 1.00 101.34 ?  4385 GLN   C HE21   1 
ATOM   6518 H  HE22   . GLN   B  2 133 ? 110.236 -30.573 -34.035 1.00 101.34 ?  4385 GLN   C HE22   1 
HETATM 6519 C  C1     . EDO   C  3 .   ? 76.306  -15.079 10.250  1.00 45.49  ?  7201 EDO   B C1     1 
HETATM 6520 O  O1     . EDO   C  3 .   ? 77.697  -15.195 9.942   1.00 60.53  ?  7201 EDO   B O1     1 
HETATM 6521 C  C2     . EDO   C  3 .   ? 75.618  -14.246 9.183   1.00 46.80  ?  7201 EDO   B C2     1 
HETATM 6522 O  O2     . EDO   C  3 .   ? 76.301  -13.001 9.008   1.00 63.01  ?  7201 EDO   B O2     1 
HETATM 6523 H  H11    . EDO   C  3 .   ? 76.181  -14.607 11.227  1.00 55.11  ?  7201 EDO   B H11    1 
HETATM 6524 H  H12    . EDO   C  3 .   ? 75.853  -16.071 10.296  1.00 55.11  ?  7201 EDO   B H12    1 
HETATM 6525 H  HO1    . EDO   C  3 .   ? 78.148  -15.662 10.658  1.00 73.16  ?  7201 EDO   B HO1    1 
HETATM 6526 H  H21    . EDO   C  3 .   ? 74.582  -14.060 9.473   1.00 56.69  ?  7201 EDO   B H21    1 
HETATM 6527 H  H22    . EDO   C  3 .   ? 75.608  -14.795 8.239   1.00 56.69  ?  7201 EDO   B H22    1 
HETATM 6528 H  HO2    . EDO   C  3 .   ? 75.982  -12.569 8.204   1.00 76.13  ?  7201 EDO   B HO2    1 
HETATM 6529 O  O1     . MES   D  4 .   ? 69.549  -34.820 -9.418  1.00 41.12  ?  7202 MES   B O1     1 
HETATM 6530 C  C2     . MES   D  4 .   ? 68.322  -34.814 -8.707  1.00 46.85  ?  7202 MES   B C2     1 
HETATM 6531 C  C3     . MES   D  4 .   ? 68.449  -35.574 -7.393  1.00 55.49  ?  7202 MES   B C3     1 
HETATM 6532 N  N4     . MES   D  4 .   ? 68.898  -36.925 -7.682  1.00 56.65  ?  7202 MES   B N4     1 
HETATM 6533 C  C5     . MES   D  4 .   ? 70.077  -37.020 -8.538  1.00 54.63  ?  7202 MES   B C5     1 
HETATM 6534 C  C6     . MES   D  4 .   ? 69.927  -36.140 -9.767  1.00 48.26  ?  7202 MES   B C6     1 
HETATM 6535 C  C7     . MES   D  4 .   ? 68.978  -37.802 -6.504  1.00 63.95  ?  7202 MES   B C7     1 
HETATM 6536 C  C8     . MES   D  4 .   ? 67.567  -38.137 -6.034  1.00 75.71  ?  7202 MES   B C8     1 
HETATM 6537 S  S      . MES   D  4 .   ? 67.467  -39.241 -4.801  1.00 75.56  ?  7202 MES   B S      1 
HETATM 6538 O  O1S    . MES   D  4 .   ? 66.430  -38.829 -3.846  1.00 51.86  ?  7202 MES   B O1S    1 
HETATM 6539 O  O2S    . MES   D  4 .   ? 68.727  -39.430 -4.071  1.00 69.87  ?  7202 MES   B O2S    1 
HETATM 6540 O  O3S    . MES   D  4 .   ? 67.040  -40.508 -5.393  1.00 60.67  ?  7202 MES   B O3S    1 
HETATM 6541 H  H21    . MES   D  4 .   ? 68.024  -33.784 -8.504  1.00 56.75  ?  7202 MES   B H21    1 
HETATM 6542 H  H22    . MES   D  4 .   ? 67.545  -35.275 -9.320  1.00 56.75  ?  7202 MES   B H22    1 
HETATM 6543 H  H31    . MES   D  4 .   ? 69.165  -35.073 -6.738  1.00 67.11  ?  7202 MES   B H31    1 
HETATM 6544 H  H32    . MES   D  4 .   ? 67.485  -35.600 -6.880  1.00 67.11  ?  7202 MES   B H32    1 
HETATM 6545 H  HN4    . MES   D  4 .   ? 68.144  -37.291 -8.246  1.00 68.51  ?  7202 MES   B HN4    1 
HETATM 6546 H  H51    . MES   D  4 .   ? 70.221  -38.058 -8.847  1.00 66.08  ?  7202 MES   B H51    1 
HETATM 6547 H  H52    . MES   D  4 .   ? 70.961  -36.713 -7.975  1.00 66.08  ?  7202 MES   B H52    1 
HETATM 6548 H  H61    . MES   D  4 .   ? 69.171  -36.569 -10.428 1.00 58.43  ?  7202 MES   B H61    1 
HETATM 6549 H  H62    . MES   D  4 .   ? 70.873  -36.114 -10.311 1.00 58.43  ?  7202 MES   B H62    1 
HETATM 6550 H  H71    . MES   D  4 .   ? 69.529  -37.301 -5.705  1.00 77.27  ?  7202 MES   B H71    1 
HETATM 6551 H  H72    . MES   D  4 .   ? 69.514  -38.719 -6.758  1.00 77.27  ?  7202 MES   B H72    1 
HETATM 6552 H  H81    . MES   D  4 .   ? 67.087  -37.212 -5.707  1.00 91.38  ?  7202 MES   B H81    1 
HETATM 6553 H  H82    . MES   D  4 .   ? 67.005  -38.524 -6.886  1.00 91.38  ?  7202 MES   B H82    1 
HETATM 6554 C  C1     . EDO   E  3 .   ? 71.331  -3.328  -12.037 1.00 57.91  ?  7203 EDO   B C1     1 
HETATM 6555 O  O1     . EDO   E  3 .   ? 72.606  -2.882  -11.574 1.00 56.14  ?  7203 EDO   B O1     1 
HETATM 6556 C  C2     . EDO   E  3 .   ? 70.503  -3.696  -10.821 1.00 54.40  ?  7203 EDO   B C2     1 
HETATM 6557 O  O2     . EDO   E  3 .   ? 70.556  -2.597  -9.911  1.00 62.29  ?  7203 EDO   B O2     1 
HETATM 6558 H  H11    . EDO   E  3 .   ? 71.448  -4.194  -12.693 1.00 70.01  ?  7203 EDO   B H11    1 
HETATM 6559 H  H12    . EDO   E  3 .   ? 70.837  -2.539  -12.608 1.00 70.01  ?  7203 EDO   B H12    1 
HETATM 6560 H  HO1    . EDO   E  3 .   ? 73.138  -2.588  -12.326 1.00 67.89  ?  7203 EDO   B HO1    1 
HETATM 6561 H  H21    . EDO   E  3 .   ? 69.470  -3.897  -11.113 1.00 65.80  ?  7203 EDO   B H21    1 
HETATM 6562 H  H22    . EDO   E  3 .   ? 70.900  -4.598  -10.350 1.00 65.80  ?  7203 EDO   B H22    1 
HETATM 6563 H  HO2    . EDO   E  3 .   ? 70.098  -2.835  -9.093  1.00 75.27  ?  7203 EDO   B HO2    1 
HETATM 6564 C  C1     . EDO   F  3 .   ? 77.615  -25.752 20.172  1.00 71.26  ?  7204 EDO   B C1     1 
HETATM 6565 O  O1     . EDO   F  3 .   ? 78.997  -25.880 19.826  1.00 59.98  ?  7204 EDO   B O1     1 
HETATM 6566 C  C2     . EDO   F  3 .   ? 77.427  -24.720 21.272  1.00 85.12  ?  7204 EDO   B C2     1 
HETATM 6567 O  O2     . EDO   F  3 .   ? 76.228  -23.973 21.044  1.00 70.66  ?  7204 EDO   B O2     1 
HETATM 6568 H  H11    . EDO   F  3 .   ? 77.045  -25.454 19.290  1.00 86.04  ?  7204 EDO   B H11    1 
HETATM 6569 H  H12    . EDO   F  3 .   ? 77.232  -26.718 20.508  1.00 86.04  ?  7204 EDO   B H12    1 
HETATM 6570 H  HO1    . EDO   F  3 .   ? 79.091  -26.519 19.107  1.00 72.50  ?  7204 EDO   B HO1    1 
HETATM 6571 H  H21    . EDO   F  3 .   ? 78.284  -24.044 21.293  1.00 102.67 ?  7204 EDO   B H21    1 
HETATM 6572 H  H22    . EDO   F  3 .   ? 77.371  -25.221 22.241  1.00 102.67 ?  7204 EDO   B H22    1 
HETATM 6573 H  HO2    . EDO   F  3 .   ? 76.169  -23.253 21.686  1.00 85.31  ?  7204 EDO   B HO2    1 
HETATM 6574 C  C1     . EDO   G  3 .   ? 93.762  -40.301 1.802   1.00 52.30  ?  7205 EDO   B C1     1 
HETATM 6575 O  O1     . EDO   G  3 .   ? 93.315  -39.183 1.020   1.00 46.73  ?  7205 EDO   B O1     1 
HETATM 6576 C  C2     . EDO   G  3 .   ? 93.671  -39.820 3.240   1.00 62.39  ?  7205 EDO   B C2     1 
HETATM 6577 O  O2     . EDO   G  3 .   ? 93.813  -38.395 3.162   1.00 58.00  ?  7205 EDO   B O2     1 
HETATM 6578 H  H11    . EDO   G  3 .   ? 94.787  -40.577 1.544   1.00 63.28  ?  7205 EDO   B H11    1 
HETATM 6579 H  H12    . EDO   G  3 .   ? 93.127  -41.174 1.639   1.00 63.28  ?  7205 EDO   B H12    1 
HETATM 6580 H  HO1    . EDO   G  3 .   ? 93.392  -39.396 0.080   1.00 56.60  ?  7205 EDO   B HO1    1 
HETATM 6581 H  H21    . EDO   G  3 .   ? 92.712  -40.094 3.684   1.00 75.39  ?  7205 EDO   B H21    1 
HETATM 6582 H  H22    . EDO   G  3 .   ? 94.462  -40.259 3.851   1.00 75.39  ?  7205 EDO   B H22    1 
HETATM 6583 H  HO2    . EDO   G  3 .   ? 93.835  -38.024 4.055   1.00 70.12  ?  7205 EDO   B HO2    1 
HETATM 6584 C  C1     . EDO   H  3 .   ? 103.238 -35.601 -0.994  1.00 65.50  ?  7206 EDO   B C1     1 
HETATM 6585 O  O1     . EDO   H  3 .   ? 103.066 -35.415 -2.395  1.00 47.50  ?  7206 EDO   B O1     1 
HETATM 6586 C  C2     . EDO   H  3 .   ? 101.894 -35.810 -0.330  1.00 76.65  ?  7206 EDO   B C2     1 
HETATM 6587 O  O2     . EDO   H  3 .   ? 100.827 -35.295 -1.123  1.00 61.81  ?  7206 EDO   B O2     1 
HETATM 6588 H  H11    . EDO   H  3 .   ? 103.729 -34.726 -0.563  1.00 79.12  ?  7206 EDO   B H11    1 
HETATM 6589 H  H12    . EDO   H  3 .   ? 103.877 -36.468 -0.813  1.00 79.12  ?  7206 EDO   B H12    1 
HETATM 6590 H  HO1    . EDO   H  3 .   ? 103.788 -34.871 -2.739  1.00 57.52  ?  7206 EDO   B HO1    1 
HETATM 6591 H  H21    . EDO   H  3 .   ? 101.891 -35.315 0.643   1.00 92.51  ?  7206 EDO   B H21    1 
HETATM 6592 H  H22    . EDO   H  3 .   ? 101.736 -36.878 -0.163  1.00 92.51  ?  7206 EDO   B H22    1 
HETATM 6593 H  HO2    . EDO   H  3 .   ? 99.997  -35.366 -0.633  1.00 74.69  ?  7206 EDO   B HO2    1 
HETATM 6594 C  C1     . EDO   I  3 .   ? 61.936  -18.279 3.049   1.00 73.99  ?  7207 EDO   B C1     1 
HETATM 6595 O  O1     . EDO   I  3 .   ? 62.410  -16.941 3.216   1.00 74.49  ?  7207 EDO   B O1     1 
HETATM 6596 C  C2     . EDO   I  3 .   ? 60.434  -18.273 2.801   1.00 76.25  ?  7207 EDO   B C2     1 
HETATM 6597 O  O2     . EDO   I  3 .   ? 59.996  -19.600 2.482   1.00 70.14  ?  7207 EDO   B O2     1 
HETATM 6598 H  H11    . EDO   I  3 .   ? 62.447  -18.749 2.206   1.00 89.31  ?  7207 EDO   B H11    1 
HETATM 6599 H  H12    . EDO   I  3 .   ? 62.159  -18.864 3.944   1.00 89.31  ?  7207 EDO   B H12    1 
HETATM 6600 H  HO1    . EDO   I  3 .   ? 63.363  -16.955 3.382   1.00 89.91  ?  7207 EDO   B HO1    1 
HETATM 6601 H  H21    . EDO   I  3 .   ? 59.912  -17.914 3.690   1.00 92.02  ?  7207 EDO   B H21    1 
HETATM 6602 H  H22    . EDO   I  3 .   ? 60.197  -17.596 1.977   1.00 92.02  ?  7207 EDO   B H22    1 
HETATM 6603 H  HO2    . EDO   I  3 .   ? 59.060  -19.581 2.238   1.00 84.69  ?  7207 EDO   B HO2    1 
HETATM 6604 C  C1     . EDO   J  3 .   ? 76.885  0.438   1.865   1.00 67.82  ?  7208 EDO   B C1     1 
HETATM 6605 O  O1     . EDO   J  3 .   ? 76.932  0.969   3.194   1.00 75.16  ?  7208 EDO   B O1     1 
HETATM 6606 C  C2     . EDO   J  3 .   ? 75.648  0.947   1.133   1.00 54.21  ?  7208 EDO   B C2     1 
HETATM 6607 O  O2     . EDO   J  3 .   ? 74.512  0.126   1.435   1.00 68.67  ?  7208 EDO   B O2     1 
HETATM 6608 H  H11    . EDO   J  3 .   ? 77.782  0.736   1.319   1.00 81.91  ?  7208 EDO   B H11    1 
HETATM 6609 H  H12    . EDO   J  3 .   ? 76.864  -0.653  1.907   1.00 81.91  ?  7208 EDO   B H12    1 
HETATM 6610 H  HO1    . EDO   J  3 .   ? 77.723  0.643   3.644   1.00 90.71  ?  7208 EDO   B HO1    1 
HETATM 6611 H  H21    . EDO   J  3 .   ? 75.444  1.978   1.430   1.00 65.57  ?  7208 EDO   B H21    1 
HETATM 6612 H  H22    . EDO   J  3 .   ? 75.830  0.937   0.056   1.00 65.57  ?  7208 EDO   B H22    1 
HETATM 6613 H  HO2    . EDO   J  3 .   ? 73.738  0.459   0.961   1.00 82.93  ?  7208 EDO   B HO2    1 
HETATM 6614 C  C1     . EDO   K  3 .   ? 68.066  -9.430  -0.386  1.00 70.68  ?  7209 EDO   B C1     1 
HETATM 6615 O  O1     . EDO   K  3 .   ? 67.806  -9.156  -1.770  1.00 65.18  ?  7209 EDO   B O1     1 
HETATM 6616 C  C2     . EDO   K  3 .   ? 66.824  -9.167  0.453   1.00 80.43  ?  7209 EDO   B C2     1 
HETATM 6617 O  O2     . EDO   K  3 .   ? 67.138  -9.238  1.844   1.00 69.75  ?  7209 EDO   B O2     1 
HETATM 6618 H  H11    . EDO   K  3 .   ? 68.885  -8.799  -0.035  1.00 85.34  ?  7209 EDO   B H11    1 
HETATM 6619 H  H12    . EDO   K  3 .   ? 68.372  -10.472 -0.271  1.00 85.34  ?  7209 EDO   B H12    1 
HETATM 6620 H  HO1    . EDO   K  3 .   ? 68.623  -9.260  -2.278  1.00 78.73  ?  7209 EDO   B HO1    1 
HETATM 6621 H  H21    . EDO   K  3 .   ? 66.425  -8.178  0.218   1.00 97.03  ?  7209 EDO   B H21    1 
HETATM 6622 H  H22    . EDO   K  3 .   ? 66.056  -9.905  0.212   1.00 97.03  ?  7209 EDO   B H22    1 
HETATM 6623 H  HO2    . EDO   K  3 .   ? 66.330  -9.126  2.363   1.00 84.23  ?  7209 EDO   B HO2    1 
HETATM 6624 C  C1     . EDO   L  3 .   ? 72.670  -38.111 -4.892  1.00 67.34  ?  7210 EDO   B C1     1 
HETATM 6625 O  O1     . EDO   L  3 .   ? 73.598  -37.796 -3.854  1.00 57.23  ?  7210 EDO   B O1     1 
HETATM 6626 C  C2     . EDO   L  3 .   ? 73.214  -37.715 -6.252  1.00 61.82  ?  7210 EDO   B C2     1 
HETATM 6627 O  O2     . EDO   L  3 .   ? 74.570  -38.138 -6.409  1.00 70.22  ?  7210 EDO   B O2     1 
HETATM 6628 H  H11    . EDO   L  3 .   ? 72.463  -39.183 -4.882  1.00 81.33  ?  7210 EDO   B H11    1 
HETATM 6629 H  H12    . EDO   L  3 .   ? 71.730  -37.586 -4.711  1.00 81.33  ?  7210 EDO   B H12    1 
HETATM 6630 H  HO1    . EDO   L  3 .   ? 73.276  -38.154 -3.015  1.00 69.19  ?  7210 EDO   B HO1    1 
HETATM 6631 H  H21    . EDO   L  3 .   ? 72.600  -38.165 -7.034  1.00 74.71  ?  7210 EDO   B H21    1 
HETATM 6632 H  H22    . EDO   L  3 .   ? 73.158  -36.630 -6.363  1.00 74.71  ?  7210 EDO   B H22    1 
HETATM 6633 H  HO2    . EDO   L  3 .   ? 74.915  -37.809 -7.250  1.00 84.79  ?  7210 EDO   B HO2    1 
HETATM 6634 C  C1     . EDO   M  3 .   ? 63.012  -33.961 2.522   1.00 51.87  ?  7211 EDO   B C1     1 
HETATM 6635 O  O1     . EDO   M  3 .   ? 62.932  -32.594 2.940   1.00 57.37  ?  7211 EDO   B O1     1 
HETATM 6636 C  C2     . EDO   M  3 .   ? 62.245  -34.790 3.535   1.00 61.92  ?  7211 EDO   B C2     1 
HETATM 6637 O  O2     . EDO   M  3 .   ? 61.147  -34.004 4.007   1.00 71.50  ?  7211 EDO   B O2     1 
HETATM 6638 H  H11    . EDO   M  3 .   ? 64.053  -34.284 2.475   1.00 62.77  ?  7211 EDO   B H11    1 
HETATM 6639 H  H12    . EDO   M  3 .   ? 62.578  -34.080 1.527   1.00 62.77  ?  7211 EDO   B H12    1 
HETATM 6640 H  HO1    . EDO   M  3 .   ? 63.076  -32.015 2.179   1.00 69.36  ?  7211 EDO   B HO1    1 
HETATM 6641 H  H21    . EDO   M  3 .   ? 61.881  -35.710 3.073   1.00 74.82  ?  7211 EDO   B H21    1 
HETATM 6642 H  H22    . EDO   M  3 .   ? 62.896  -35.067 4.367   1.00 74.82  ?  7211 EDO   B H22    1 
HETATM 6643 H  HO2    . EDO   M  3 .   ? 60.653  -34.506 4.670   1.00 86.32  ?  7211 EDO   B HO2    1 
HETATM 6644 C  C1     . EDO   N  3 .   ? 78.692  -20.617 -22.558 1.00 65.33  ?  7212 EDO   B C1     1 
HETATM 6645 O  O1     . EDO   N  3 .   ? 77.730  -19.871 -23.307 1.00 75.21  ?  7212 EDO   B O1     1 
HETATM 6646 C  C2     . EDO   N  3 .   ? 78.142  -20.947 -21.181 1.00 60.85  ?  7212 EDO   B C2     1 
HETATM 6647 O  O2     . EDO   N  3 .   ? 77.160  -21.975 -21.291 1.00 67.32  ?  7212 EDO   B O2     1 
HETATM 6648 H  H11    . EDO   N  3 .   ? 79.611  -20.036 -22.458 1.00 78.91  ?  7212 EDO   B H11    1 
HETATM 6649 H  H12    . EDO   N  3 .   ? 78.934  -21.541 -23.088 1.00 78.91  ?  7212 EDO   B H12    1 
HETATM 6650 H  HO1    . EDO   N  3 .   ? 78.084  -19.680 -24.186 1.00 90.78  ?  7212 EDO   B HO1    1 
HETATM 6651 H  H21    . EDO   N  3 .   ? 77.697  -20.054 -20.737 1.00 73.54  ?  7212 EDO   B H21    1 
HETATM 6652 H  H22    . EDO   N  3 .   ? 78.953  -21.278 -20.529 1.00 73.54  ?  7212 EDO   B H22    1 
HETATM 6653 H  HO2    . EDO   N  3 .   ? 76.826  -22.197 -20.411 1.00 81.30  ?  7212 EDO   B HO2    1 
HETATM 6654 C  C1     . EDO   O  3 .   ? 83.489  -25.577 12.196  1.00 64.47  ?  7213 EDO   B C1     1 
HETATM 6655 O  O1     . EDO   O  3 .   ? 83.780  -24.507 11.293  1.00 62.89  ?  7213 EDO   B O1     1 
HETATM 6656 C  C2     . EDO   O  3 .   ? 84.487  -26.701 11.973  1.00 69.31  ?  7213 EDO   B C2     1 
HETATM 6657 O  O2     . EDO   O  3 .   ? 83.956  -27.936 12.452  1.00 53.01  ?  7213 EDO   B O2     1 
HETATM 6658 H  H11    . EDO   O  3 .   ? 82.473  -25.941 12.028  1.00 77.89  ?  7213 EDO   B H11    1 
HETATM 6659 H  H12    . EDO   O  3 .   ? 83.552  -25.222 13.227  1.00 77.89  ?  7213 EDO   B H12    1 
HETATM 6660 H  HO1    . EDO   O  3 .   ? 83.081  -23.841 11.346  1.00 75.99  ?  7213 EDO   B HO1    1 
HETATM 6661 H  H21    . EDO   O  3 .   ? 84.712  -26.786 10.908  1.00 83.69  ?  7213 EDO   B H21    1 
HETATM 6662 H  H22    . EDO   O  3 .   ? 85.419  -26.474 12.495  1.00 83.69  ?  7213 EDO   B H22    1 
HETATM 6663 H  HO2    . EDO   O  3 .   ? 84.615  -28.635 12.340  1.00 64.14  ?  7213 EDO   B HO2    1 
HETATM 6664 C  C1     . EDO   P  3 .   ? 73.516  -35.852 -14.381 1.00 58.47  ?  7214 EDO   B C1     1 
HETATM 6665 O  O1     . EDO   P  3 .   ? 74.387  -36.930 -14.035 1.00 66.87  ?  7214 EDO   B O1     1 
HETATM 6666 C  C2     . EDO   P  3 .   ? 72.102  -36.120 -13.894 1.00 62.57  ?  7214 EDO   B C2     1 
HETATM 6667 O  O2     . EDO   P  3 .   ? 71.966  -37.435 -13.353 1.00 77.96  ?  7214 EDO   B O2     1 
HETATM 6668 H  H11    . EDO   P  3 .   ? 73.509  -35.723 -15.465 1.00 70.69  ?  7214 EDO   B H11    1 
HETATM 6669 H  H12    . EDO   P  3 .   ? 73.885  -34.927 -13.934 1.00 70.69  ?  7214 EDO   B H12    1 
HETATM 6670 H  HO1    . EDO   P  3 .   ? 75.284  -36.729 -14.337 1.00 80.77  ?  7214 EDO   B HO1    1 
HETATM 6671 H  H21    . EDO   P  3 .   ? 71.405  -36.000 -14.726 1.00 75.61  ?  7214 EDO   B H21    1 
HETATM 6672 H  H22    . EDO   P  3 .   ? 71.840  -35.387 -13.128 1.00 75.61  ?  7214 EDO   B H22    1 
HETATM 6673 H  HO2    . EDO   P  3 .   ? 71.062  -37.561 -13.033 1.00 94.07  ?  7214 EDO   B HO2    1 
HETATM 6674 C  C1     . EDO   Q  3 .   ? 104.305 -26.336 -6.961  1.00 60.04  ?  7215 EDO   B C1     1 
HETATM 6675 O  O1     . EDO   Q  3 .   ? 103.140 -25.704 -6.442  1.00 63.20  ?  7215 EDO   B O1     1 
HETATM 6676 C  C2     . EDO   Q  3 .   ? 104.397 -27.764 -6.459  1.00 68.29  ?  7215 EDO   B C2     1 
HETATM 6677 O  O2     . EDO   Q  3 .   ? 104.224 -27.833 -5.045  1.00 61.75  ?  7215 EDO   B O2     1 
HETATM 6678 H  H11    . EDO   Q  3 .   ? 105.193 -25.781 -6.653  1.00 72.57  ?  7215 EDO   B H11    1 
HETATM 6679 H  H12    . EDO   Q  3 .   ? 104.269 -26.332 -8.053  1.00 72.57  ?  7215 EDO   B H12    1 
HETATM 6680 H  HO1    . EDO   Q  3 .   ? 103.070 -24.810 -6.803  1.00 76.36  ?  7215 EDO   B HO1    1 
HETATM 6681 H  H21    . EDO   Q  3 .   ? 105.372 -28.179 -6.725  1.00 82.47  ?  7215 EDO   B H21    1 
HETATM 6682 H  H22    . EDO   Q  3 .   ? 103.630 -28.369 -6.947  1.00 82.47  ?  7215 EDO   B H22    1 
HETATM 6683 H  HO2    . EDO   Q  3 .   ? 104.308 -28.752 -4.754  1.00 74.62  ?  7215 EDO   B HO2    1 
HETATM 6684 C  C1     D EDO   R  3 .   ? 85.190  -23.271 7.514   0.95 55.38  ?  7216 EDO   B C1     1 
HETATM 6685 O  O1     D EDO   R  3 .   ? 86.090  -22.959 6.447   0.95 74.22  ?  7216 EDO   B O1     1 
HETATM 6686 C  C2     D EDO   R  3 .   ? 84.854  -24.751 7.558   0.95 55.44  ?  7216 EDO   B C2     1 
HETATM 6687 O  O2     D EDO   R  3 .   ? 86.034  -25.556 7.450   0.95 50.63  ?  7216 EDO   B O2     1 
HETATM 6688 H  H11    D EDO   R  3 .   ? 85.643  -22.977 8.463   0.95 66.97  ?  7216 EDO   B H11    1 
HETATM 6689 H  H12    D EDO   R  3 .   ? 84.270  -22.697 7.389   0.95 66.97  ?  7216 EDO   B H12    1 
HETATM 6690 H  HO1    D EDO   R  3 .   ? 86.234  -22.004 6.416   0.95 89.59  ?  7216 EDO   B HO1    1 
HETATM 6691 H  H21    D EDO   R  3 .   ? 84.173  -24.992 6.738   0.95 67.05  ?  7216 EDO   B H21    1 
HETATM 6692 H  H22    D EDO   R  3 .   ? 84.343  -24.979 8.496   0.95 67.05  ?  7216 EDO   B H22    1 
HETATM 6693 H  HO2    D EDO   R  3 .   ? 85.812  -26.480 7.632   0.95 61.27  ?  7216 EDO   B HO2    1 
HETATM 6694 C  C1     . EDO   S  3 .   ? 74.991  -43.815 6.497   1.00 66.05  ?  7217 EDO   B C1     1 
HETATM 6695 O  O1     . EDO   S  3 .   ? 73.940  -43.969 7.448   1.00 64.63  ?  7217 EDO   B O1     1 
HETATM 6696 C  C2     . EDO   S  3 .   ? 74.577  -44.351 5.141   1.00 61.51  ?  7217 EDO   B C2     1 
HETATM 6697 O  O2     . EDO   S  3 .   ? 73.352  -43.760 4.708   1.00 62.96  ?  7217 EDO   B O2     1 
HETATM 6698 H  H11    . EDO   S  3 .   ? 75.879  -44.348 6.844   1.00 79.78  ?  7217 EDO   B H11    1 
HETATM 6699 H  H12    . EDO   S  3 .   ? 75.249  -42.757 6.407   1.00 79.78  ?  7217 EDO   B H12    1 
HETATM 6700 H  HO1    . EDO   S  3 .   ? 74.238  -43.654 8.313   1.00 78.07  ?  7217 EDO   B HO1    1 
HETATM 6701 H  H21    . EDO   S  3 .   ? 74.457  -45.435 5.200   1.00 74.34  ?  7217 EDO   B H21    1 
HETATM 6702 H  H22    . EDO   S  3 .   ? 75.361  -44.140 4.411   1.00 74.34  ?  7217 EDO   B H22    1 
HETATM 6703 H  HO2    . EDO   S  3 .   ? 73.072  -44.169 3.878   1.00 76.07  ?  7217 EDO   B HO2    1 
HETATM 6704 C  C1     . EDO   T  3 .   ? 99.321  -25.156 -0.955  1.00 61.96  ?  7218 EDO   B C1     1 
HETATM 6705 O  O1     . EDO   T  3 .   ? 100.754 -25.203 -0.843  1.00 76.25  ?  7218 EDO   B O1     1 
HETATM 6706 C  C2     . EDO   T  3 .   ? 98.807  -23.948 -0.188  1.00 72.75  ?  7218 EDO   B C2     1 
HETATM 6707 O  O2     . EDO   T  3 .   ? 97.422  -24.093 0.121   1.00 69.23  ?  7218 EDO   B O2     1 
HETATM 6708 H  H11    . EDO   T  3 .   ? 98.884  -26.070 -0.548  1.00 74.87  ?  7218 EDO   B H11    1 
HETATM 6709 H  H12    . EDO   T  3 .   ? 99.031  -25.083 -2.005  1.00 74.87  ?  7218 EDO   B H12    1 
HETATM 6710 H  HO1    . EDO   T  3 .   ? 101.089 -25.977 -1.317  1.00 92.02  ?  7218 EDO   B HO1    1 
HETATM 6711 H  H21    . EDO   T  3 .   ? 99.376  -23.834 0.737   1.00 87.82  ?  7218 EDO   B H21    1 
HETATM 6712 H  H22    . EDO   T  3 .   ? 98.954  -23.046 -0.786  1.00 87.82  ?  7218 EDO   B H22    1 
HETATM 6713 H  HO2    . EDO   T  3 .   ? 97.131  -23.343 0.657   1.00 83.60  ?  7218 EDO   B HO2    1 
HETATM 6714 N  N1     . A1IOL U  5 .   ? 84.910  -31.423 18.980  1.00 75.53  ?  7219 A1IOL B N1     1 
HETATM 6715 N  N3     . A1IOL U  5 .   ? 83.594  -29.934 16.211  1.00 63.98  ?  7219 A1IOL B N3     1 
HETATM 6716 C  C4     . A1IOL U  5 .   ? 84.006  -30.756 17.189  1.00 61.38  ?  7219 A1IOL B C4     1 
HETATM 6717 C  C5     . A1IOL U  5 .   ? 82.823  -30.476 15.082  1.00 51.71  ?  7219 A1IOL B C5     1 
HETATM 6718 C  C6     . A1IOL U  5 .   ? 85.733  -31.600 20.224  1.00 81.37  ?  7219 A1IOL B C6     1 
HETATM 6719 C  C7     . A1IOL U  5 .   ? 84.949  -31.289 21.428  1.00 73.33  ?  7219 A1IOL B C7     1 
HETATM 6720 C  C8     . A1IOL U  5 .   ? 85.489  -32.098 22.611  1.00 85.61  ?  7219 A1IOL B C8     1 
HETATM 6721 C  C10    . A1IOL U  5 .   ? 87.995  -31.367 22.498  1.00 98.01  ?  7219 A1IOL B C10    1 
HETATM 6722 C  C13    . A1IOL U  5 .   ? 89.313  -33.496 18.562  1.00 93.17  ?  7219 A1IOL B C13    1 
HETATM 6723 C  C15    . A1IOL U  5 .   ? 88.983  -36.024 18.498  1.00 83.08  ?  7219 A1IOL B C15    1 
HETATM 6724 C  C20    . A1IOL U  5 .   ? 84.947  -29.827 21.738  1.00 75.08  ?  7219 A1IOL B C20    1 
HETATM 6725 C  C21    . A1IOL U  5 .   ? 84.943  -26.694 17.380  1.00 70.86  ?  7219 A1IOL B C21    1 
HETATM 6726 N  N      . A1IOL U  5 .   ? 84.620  -28.134 17.321  1.00 66.66  ?  7219 A1IOL B N      1 
HETATM 6727 C  C      . A1IOL U  5 .   ? 83.898  -28.601 16.260  1.00 61.16  ?  7219 A1IOL B C      1 
HETATM 6728 O  O      . A1IOL U  5 .   ? 83.541  -27.872 15.388  1.00 65.14  ?  7219 A1IOL B O      1 
HETATM 6729 C  C1     . A1IOL U  5 .   ? 85.033  -28.978 18.316  1.00 73.95  ?  7219 A1IOL B C1     1 
HETATM 6730 C  C11    . A1IOL U  5 .   ? 89.594  -32.067 20.620  1.00 103.48 ?  7219 A1IOL B C11    1 
HETATM 6731 C  C12    . A1IOL U  5 .   ? 90.023  -32.247 19.123  1.00 104.80 ?  7219 A1IOL B C12    1 
HETATM 6732 C  C14    . A1IOL U  5 .   ? 89.818  -34.864 19.113  1.00 92.83  ?  7219 A1IOL B C14    1 
HETATM 6733 C  C16    . A1IOL U  5 .   ? 87.787  -36.440 19.385  1.00 96.97  ?  7219 A1IOL B C16    1 
HETATM 6734 C  C19    . A1IOL U  5 .   ? 87.209  -31.011 20.047  1.00 91.60  ?  7219 A1IOL B C19    1 
HETATM 6735 C  C2     . A1IOL U  5 .   ? 84.736  -30.337 18.286  1.00 71.99  ?  7219 A1IOL B C2     1 
HETATM 6736 C  C3     . A1IOL U  5 .   ? 84.447  -32.482 18.567  1.00 67.30  ?  7219 A1IOL B C3     1 
HETATM 6737 C  C9     . A1IOL U  5 .   ? 86.969  -32.434 22.847  1.00 92.11  ?  7219 A1IOL B C9     1 
HETATM 6738 N  N2     . A1IOL U  5 .   ? 83.828  -32.160 17.378  1.00 56.56  ?  7219 A1IOL B N2     1 
HETATM 6739 N  N4     . A1IOL U  5 .   ? 88.236  -31.455 21.057  1.00 95.30  ?  7219 A1IOL B N4     1 
HETATM 6740 N  N5     . A1IOL U  5 .   ? 91.452  -32.339 19.032  1.00 106.00 ?  7219 A1IOL B N5     1 
HETATM 6741 N  N6     . A1IOL U  5 .   ? 86.739  -35.422 19.396  1.00 77.32  ?  7219 A1IOL B N6     1 
HETATM 6742 O  O1     . A1IOL U  5 .   ? 85.652  -28.512 19.203  1.00 75.70  ?  7219 A1IOL B O1     1 
HETATM 6743 O  O2     . A1IOL U  5 .   ? 83.678  -31.749 21.114  1.00 81.02  ?  7219 A1IOL B O2     1 
HETATM 6744 O  O3     . A1IOL U  5 .   ? 87.268  -33.564 22.061  1.00 98.65  ?  7219 A1IOL B O3     1 
HETATM 6745 O  O4     . A1IOL U  5 .   ? 90.369  -32.428 21.456  1.00 108.44 ?  7219 A1IOL B O4     1 
HETATM 6746 H  H4     . A1IOL U  5 .   ? 83.322  -31.364 14.694  1.00 62.58  ?  7219 A1IOL B H4     1 
HETATM 6747 H  H6     . A1IOL U  5 .   ? 81.821  -30.740 15.419  1.00 62.58  ?  7219 A1IOL B H6     1 
HETATM 6748 H  H5     . A1IOL U  5 .   ? 82.755  -29.725 14.294  1.00 62.58  ?  7219 A1IOL B H5     1 
HETATM 6749 H  H      . A1IOL U  5 .   ? 85.970  -32.640 20.407  1.00 98.16  ?  7219 A1IOL B H      1 
HETATM 6750 H  H9     . A1IOL U  5 .   ? 85.168  -31.565 23.496  1.00 103.26 ?  7219 A1IOL B H9     1 
HETATM 6751 H  H8     . A1IOL U  5 .   ? 84.979  -33.052 22.566  1.00 103.26 ?  7219 A1IOL B H8     1 
HETATM 6752 H  H12    . A1IOL U  5 .   ? 88.916  -31.544 23.042  1.00 118.14 ?  7219 A1IOL B H12    1 
HETATM 6753 H  H11    . A1IOL U  5 .   ? 87.614  -30.385 22.754  1.00 118.14 ?  7219 A1IOL B H11    1 
HETATM 6754 H  H15    . A1IOL U  5 .   ? 88.258  -33.412 18.793  1.00 112.33 ?  7219 A1IOL B H15    1 
HETATM 6755 H  H16    . A1IOL U  5 .   ? 89.447  -33.500 17.487  1.00 112.33 ?  7219 A1IOL B H16    1 
HETATM 6756 H  H19    . A1IOL U  5 .   ? 89.628  -36.879 18.365  1.00 100.22 ?  7219 A1IOL B H19    1 
HETATM 6757 H  H20    . A1IOL U  5 .   ? 88.607  -35.706 17.538  1.00 100.22 ?  7219 A1IOL B H20    1 
HETATM 6758 H  H29    . A1IOL U  5 .   ? 84.496  -29.664 22.709  1.00 90.62  ?  7219 A1IOL B H29    1 
HETATM 6759 H  H31    . A1IOL U  5 .   ? 84.377  -29.299 20.983  1.00 90.62  ?  7219 A1IOL B H31    1 
HETATM 6760 H  H30    . A1IOL U  5 .   ? 85.965  -29.458 21.745  1.00 90.62  ?  7219 A1IOL B H30    1 
HETATM 6761 H  H32    . A1IOL U  5 .   ? 86.006  -26.553 17.202  1.00 85.56  ?  7219 A1IOL B H32    1 
HETATM 6762 H  H33    . A1IOL U  5 .   ? 84.375  -26.164 16.620  1.00 85.56  ?  7219 A1IOL B H33    1 
HETATM 6763 H  H34    . A1IOL U  5 .   ? 84.685  -26.305 18.362  1.00 85.56  ?  7219 A1IOL B H34    1 
HETATM 6764 H  H2     . A1IOL U  5 .   ? 89.729  -31.399 18.532  1.00 126.29 ?  7219 A1IOL B H2     1 
HETATM 6765 H  H18    . A1IOL U  5 .   ? 89.711  -34.878 20.190  1.00 111.92 ?  7219 A1IOL B H18    1 
HETATM 6766 H  H17    . A1IOL U  5 .   ? 90.859  -34.994 18.852  1.00 111.92 ?  7219 A1IOL B H17    1 
HETATM 6767 H  H22    . A1IOL U  5 .   ? 87.372  -37.368 19.003  1.00 116.89 ?  7219 A1IOL B H22    1 
HETATM 6768 H  H21    . A1IOL U  5 .   ? 88.139  -36.593 20.401  1.00 116.89 ?  7219 A1IOL B H21    1 
HETATM 6769 H  H27    . A1IOL U  5 .   ? 87.564  -31.300 19.067  1.00 110.44 ?  7219 A1IOL B H27    1 
HETATM 6770 H  H28    . A1IOL U  5 .   ? 87.142  -29.933 20.097  1.00 110.44 ?  7219 A1IOL B H28    1 
HETATM 6771 H  H3     . A1IOL U  5 .   ? 84.261  -33.364 19.158  1.00 81.29  ?  7219 A1IOL B H3     1 
HETATM 6772 H  H1     . A1IOL U  5 .   ? 87.056  -32.568 23.923  1.00 111.06 ?  7219 A1IOL B H1     1 
HETATM 6773 H  H13    . A1IOL U  5 .   ? 91.726  -32.289 18.073  1.00 127.73 ?  7219 A1IOL B H13    1 
HETATM 6774 H  H35    . A1IOL U  5 .   ? 91.867  -31.557 19.520  1.00 127.73 ?  7219 A1IOL B H35    1 
HETATM 6775 H  H23    . A1IOL U  5 .   ? 86.023  -35.664 18.745  1.00 93.31  ?  7219 A1IOL B H23    1 
HETATM 6776 H  H7     . A1IOL U  5 .   ? 83.201  -31.879 21.909  1.00 97.75  ?  7219 A1IOL B H7     1 
HETATM 6777 H  H10    . A1IOL U  5 .   ? 87.832  -34.186 22.488  1.00 118.90 ?  7219 A1IOL B H10    1 
HETATM 6778 H  H292   . A1IOL U  5 .   ? 86.339  -35.374 20.316  1.00 93.31  ?  7219 A1IOL B H292   1 
HETATM 6779 N  N      . SAM   V  6 .   ? 85.930  -18.906 -1.251  1.00 50.64  ?  7220 SAM   B N      1 
HETATM 6780 C  CA     . SAM   V  6 .   ? 87.129  -18.452 -0.629  1.00 56.65  ?  7220 SAM   B CA     1 
HETATM 6781 C  C      . SAM   V  6 .   ? 88.136  -19.274 -1.392  1.00 57.04  ?  7220 SAM   B C      1 
HETATM 6782 O  O      . SAM   V  6 .   ? 89.216  -19.619 -0.927  1.00 64.10  ?  7220 SAM   B O      1 
HETATM 6783 O  OXT    . SAM   V  6 .   ? 87.823  -19.702 -2.501  1.00 56.44  -1 7220 SAM   B OXT    1 
HETATM 6784 C  CB     . SAM   V  6 .   ? 87.102  -18.726 0.848   1.00 61.76  ?  7220 SAM   B CB     1 
HETATM 6785 C  CG     . SAM   V  6 .   ? 86.114  -17.751 1.501   1.00 61.82  ?  7220 SAM   B CG     1 
HETATM 6786 S  SD     . SAM   V  6 .   ? 86.242  -17.664 3.223   1.00 83.62  ?  7220 SAM   B SD     1 
HETATM 6787 C  CE     . SAM   V  6 .   ? 86.400  -19.221 3.835   1.00 78.53  ?  7220 SAM   B CE     1 
HETATM 6788 C  "C5'"  . SAM   V  6 .   ? 84.900  -16.896 3.912   1.00 68.02  ?  7220 SAM   B "C5'"  1 
HETATM 6789 C  "C4'"  . SAM   V  6 .   ? 84.523  -15.617 3.208   1.00 61.24  ?  7220 SAM   B "C4'"  1 
HETATM 6790 O  "O4'"  . SAM   V  6 .   ? 83.310  -15.172 3.440   1.00 62.04  ?  7220 SAM   B "O4'"  1 
HETATM 6791 C  "C3'"  . SAM   V  6 .   ? 85.512  -14.324 3.539   1.00 63.86  ?  7220 SAM   B "C3'"  1 
HETATM 6792 O  "O3'"  . SAM   V  6 .   ? 86.374  -14.168 2.373   1.00 62.85  ?  7220 SAM   B "O3'"  1 
HETATM 6793 C  "C2'"  . SAM   V  6 .   ? 84.801  -13.362 3.881   1.00 63.84  ?  7220 SAM   B "C2'"  1 
HETATM 6794 O  "O2'"  . SAM   V  6 .   ? 85.370  -12.026 3.574   1.00 57.05  ?  7220 SAM   B "O2'"  1 
HETATM 6795 C  "C1'"  . SAM   V  6 .   ? 83.328  -13.632 3.334   1.00 63.37  ?  7220 SAM   B "C1'"  1 
HETATM 6796 N  N9     . SAM   V  6 .   ? 82.263  -12.917 3.713   1.00 67.36  ?  7220 SAM   B N9     1 
HETATM 6797 C  C8     . SAM   V  6 .   ? 82.037  -13.186 4.932   1.00 55.31  ?  7220 SAM   B C8     1 
HETATM 6798 N  N7     . SAM   V  6 .   ? 80.990  -12.473 5.303   1.00 62.15  ?  7220 SAM   B N7     1 
HETATM 6799 C  C5     . SAM   V  6 .   ? 80.540  -11.718 4.345   1.00 64.10  ?  7220 SAM   B C5     1 
HETATM 6800 C  C6     . SAM   V  6 .   ? 79.480  -10.819 4.255   1.00 61.02  ?  7220 SAM   B C6     1 
HETATM 6801 N  N6     . SAM   V  6 .   ? 78.416  -10.264 5.175   1.00 56.88  ?  7220 SAM   B N6     1 
HETATM 6802 N  N1     . SAM   V  6 .   ? 79.306  -10.237 3.097   1.00 53.36  ?  7220 SAM   B N1     1 
HETATM 6803 C  C2     . SAM   V  6 .   ? 80.082  -10.499 2.067   1.00 59.48  ?  7220 SAM   B C2     1 
HETATM 6804 N  N3     . SAM   V  6 .   ? 81.062  -11.384 2.237   1.00 56.80  ?  7220 SAM   B N3     1 
HETATM 6805 C  C4     . SAM   V  6 .   ? 81.328  -12.009 3.351   1.00 67.12  ?  7220 SAM   B C4     1 
HETATM 6806 H  HN1    . SAM   V  6 .   ? 85.263  -18.215 -1.441  1.00 61.29  ?  7220 SAM   B HN1    1 
HETATM 6807 H  HN2    . SAM   V  6 .   ? 85.550  -19.699 -0.839  1.00 61.29  ?  7220 SAM   B HN2    1 
HETATM 6808 H  HA     . SAM   V  6 .   ? 87.323  -17.386 -0.671  1.00 68.51  ?  7220 SAM   B HA     1 
HETATM 6809 H  HB1    . SAM   V  6 .   ? 86.783  -19.746 1.026   1.00 74.63  ?  7220 SAM   B HB1    1 
HETATM 6810 H  HB2    . SAM   V  6 .   ? 88.092  -18.579 1.265   1.00 74.63  ?  7220 SAM   B HB2    1 
HETATM 6811 H  HG1    . SAM   V  6 .   ? 86.297  -16.743 1.088   1.00 74.71  ?  7220 SAM   B HG1    1 
HETATM 6812 H  HG2    . SAM   V  6 .   ? 85.089  -18.074 1.245   1.00 74.71  ?  7220 SAM   B HG2    1 
HETATM 6813 H  HE1    . SAM   V  6 .   ? 85.971  -19.264 4.821   1.00 94.75  ?  7220 SAM   B HE1    1 
HETATM 6814 H  HE2    . SAM   V  6 .   ? 87.442  -19.483 3.886   1.00 94.75  ?  7220 SAM   B HE2    1 
HETATM 6815 H  HE3    . SAM   V  6 .   ? 85.887  -19.914 3.190   1.00 94.75  ?  7220 SAM   B HE3    1 
HETATM 6816 H  "H5'1" . SAM   V  6 .   ? 84.061  -17.571 3.871   1.00 82.14  ?  7220 SAM   B "H5'1" 1 
HETATM 6817 H  "H5'2" . SAM   V  6 .   ? 85.128  -16.668 4.941   1.00 82.14  ?  7220 SAM   B "H5'2" 1 
HETATM 6818 H  "H4'"  . SAM   V  6 .   ? 84.602  -15.887 2.135   1.00 74.02  ?  7220 SAM   B "H4'"  1 
HETATM 6819 H  "H3'"  . SAM   V  6 .   ? 86.123  -14.445 4.411   1.00 77.16  ?  7220 SAM   B "H3'"  1 
HETATM 6820 H  "HO3'" . SAM   V  6 .   ? 85.922  -14.407 1.607   1.00 75.94  ?  7220 SAM   B "HO3'" 1 
HETATM 6821 H  "H2'"  . SAM   V  6 .   ? 84.731  -13.380 4.970   1.00 77.13  ?  7220 SAM   B "H2'"  1 
HETATM 6822 H  "HO2'" . SAM   V  6 .   ? 85.711  -11.933 2.705   1.00 68.98  ?  7220 SAM   B "HO2'" 1 
HETATM 6823 H  "H1'"  . SAM   V  6 .   ? 83.237  -13.260 2.313   1.00 76.57  ?  7220 SAM   B "H1'"  1 
HETATM 6824 H  H8     . SAM   V  6 .   ? 82.596  -13.868 5.549   1.00 66.89  ?  7220 SAM   B H8     1 
HETATM 6825 H  HN61   . SAM   V  6 .   ? 77.454  -10.115 4.896   1.00 68.78  ?  7220 SAM   B HN61   1 
HETATM 6826 H  HN62   . SAM   V  6 .   ? 78.654  -10.051 6.131   1.00 68.78  ?  7220 SAM   B HN62   1 
HETATM 6827 H  H2     . SAM   V  6 .   ? 79.928  -10.006 1.102   1.00 71.90  ?  7220 SAM   B H2     1 
HETATM 6828 CL CL     . CL    W  7 .   ? 61.344  -30.863 8.516   1.00 64.03  ?  7221 CL    B CL     1 
HETATM 6829 CL CL     . CL    X  7 .   ? 58.805  -15.988 -13.641 1.00 77.16  ?  7222 CL    B CL     1 
HETATM 6830 C  C1     . EDO   Y  3 .   ? 66.857  -36.434 20.225  1.00 82.81  ?  7223 EDO   B C1     1 
HETATM 6831 O  O1     . EDO   Y  3 .   ? 65.740  -35.941 19.479  1.00 69.30  ?  7223 EDO   B O1     1 
HETATM 6832 C  C2     . EDO   Y  3 .   ? 67.972  -35.395 20.281  1.00 69.27  ?  7223 EDO   B C2     1 
HETATM 6833 O  O2     . EDO   Y  3 .   ? 68.738  -35.404 19.073  1.00 63.75  ?  7223 EDO   B O2     1 
HETATM 6834 H  H11    . EDO   Y  3 .   ? 67.233  -37.347 19.759  1.00 99.89  ?  7223 EDO   B H11    1 
HETATM 6835 H  H12    . EDO   Y  3 .   ? 66.538  -36.681 21.240  1.00 99.89  ?  7223 EDO   B H12    1 
HETATM 6836 H  HO1    . EDO   Y  3 .   ? 65.064  -36.630 19.418  1.00 83.68  ?  7223 EDO   B HO1    1 
HETATM 6837 H  H21    . EDO   Y  3 .   ? 67.540  -34.404 20.431  1.00 83.65  ?  7223 EDO   B H21    1 
HETATM 6838 H  H22    . EDO   Y  3 .   ? 68.627  -35.608 21.128  1.00 83.65  ?  7223 EDO   B H22    1 
HETATM 6839 H  HO2    . EDO   Y  3 .   ? 69.492  -34.806 19.166  1.00 77.02  ?  7223 EDO   B HO2    1 
HETATM 6840 C  C1     . EDO   Z  3 .   ? 83.749  -38.936 -8.875  1.00 56.99  ?  7224 EDO   B C1     1 
HETATM 6841 O  O1     . EDO   Z  3 .   ? 84.529  -39.662 -7.922  1.00 70.65  ?  7224 EDO   B O1     1 
HETATM 6842 C  C2     . EDO   Z  3 .   ? 84.545  -37.782 -9.452  1.00 57.41  ?  7224 EDO   B C2     1 
HETATM 6843 O  O2     . EDO   Z  3 .   ? 85.683  -38.261 -10.176 1.00 68.06  ?  7224 EDO   B O2     1 
HETATM 6844 H  H11    . EDO   Z  3 .   ? 83.441  -39.606 -9.680  1.00 68.91  ?  7224 EDO   B H11    1 
HETATM 6845 H  H12    . EDO   Z  3 .   ? 82.847  -38.554 -8.393  1.00 68.91  ?  7224 EDO   B H12    1 
HETATM 6846 H  HO1    . EDO   Z  3 .   ? 84.024  -40.423 -7.604  1.00 85.30  ?  7224 EDO   B HO1    1 
HETATM 6847 H  H21    . EDO   Z  3 .   ? 83.908  -37.196 -10.118 1.00 69.41  ?  7224 EDO   B H21    1 
HETATM 6848 H  H22    . EDO   Z  3 .   ? 84.876  -37.127 -8.643  1.00 69.41  ?  7224 EDO   B H22    1 
HETATM 6849 H  HO2    . EDO   Z  3 .   ? 86.197  -37.510 -10.502 1.00 82.19  ?  7224 EDO   B HO2    1 
HETATM 6850 C  C1     . EDO   AA 3 .   ? 69.474  -7.435  -5.915  1.00 64.88  ?  7225 EDO   B C1     1 
HETATM 6851 O  O1     . EDO   AA 3 .   ? 69.122  -6.876  -7.183  1.00 67.14  ?  7225 EDO   B O1     1 
HETATM 6852 C  C2     . EDO   AA 3 .   ? 68.443  -8.473  -5.497  1.00 75.53  ?  7225 EDO   B C2     1 
HETATM 6853 O  O2     . EDO   AA 3 .   ? 68.563  -8.765  -4.099  1.00 74.36  ?  7225 EDO   B O2     1 
HETATM 6854 H  H11    . EDO   AA 3 .   ? 69.523  -6.643  -5.165  1.00 78.37  ?  7225 EDO   B H11    1 
HETATM 6855 H  H12    . EDO   AA 3 .   ? 70.460  -7.900  -5.978  1.00 78.37  ?  7225 EDO   B H12    1 
HETATM 6856 H  HO1    . EDO   AA 3 .   ? 69.785  -6.221  -7.442  1.00 81.09  ?  7225 EDO   B HO1    1 
HETATM 6857 H  H21    . EDO   AA 3 .   ? 68.589  -9.388  -6.076  1.00 91.15  ?  7225 EDO   B H21    1 
HETATM 6858 H  H22    . EDO   AA 3 .   ? 67.439  -8.099  -5.709  1.00 91.15  ?  7225 EDO   B H22    1 
HETATM 6859 H  HO2    . EDO   AA 3 .   ? 67.885  -9.406  -3.844  1.00 89.75  ?  7225 EDO   B HO2    1 
HETATM 6860 C  C1     . EDO   BA 3 .   ? 88.181  -11.714 1.742   1.00 63.45  ?  7226 EDO   B C1     1 
HETATM 6861 O  O1     . EDO   BA 3 .   ? 88.816  -12.280 2.890   1.00 70.91  ?  7226 EDO   B O1     1 
HETATM 6862 C  C2     . EDO   BA 3 .   ? 89.195  -11.494 0.632   1.00 57.30  ?  7226 EDO   B C2     1 
HETATM 6863 O  O2     . EDO   BA 3 .   ? 88.676  -10.514 -0.270  1.00 70.50  ?  7226 EDO   B O2     1 
HETATM 6864 H  H11    . EDO   BA 3 .   ? 87.393  -12.384 1.391   1.00 76.67  ?  7226 EDO   B H11    1 
HETATM 6865 H  H12    . EDO   BA 3 .   ? 87.718  -10.762 2.010   1.00 76.67  ?  7226 EDO   B H12    1 
HETATM 6866 H  HO1    . EDO   BA 3 .   ? 88.208  -12.248 3.642   1.00 85.61  ?  7226 EDO   B HO1    1 
HETATM 6867 H  H21    . EDO   BA 3 .   ? 89.380  -12.431 0.102   1.00 69.28  ?  7226 EDO   B H21    1 
HETATM 6868 H  H22    . EDO   BA 3 .   ? 90.143  -11.153 1.052   1.00 69.28  ?  7226 EDO   B H22    1 
HETATM 6869 H  HO2    . EDO   BA 3 .   ? 89.365  -10.257 -0.898  1.00 85.12  ?  7226 EDO   B HO2    1 
HETATM 6870 ZN ZN     . ZN    CA 8 .   ? 96.858  -9.328  -14.804 1.00 51.12  ?  4401 ZN    C ZN     1 
HETATM 6871 ZN ZN     . ZN    DA 8 .   ? 105.984 -22.079 -31.832 1.00 75.00  ?  4402 ZN    C ZN     1 
HETATM 6872 C  C1     . EDO   EA 3 .   ? 103.373 -13.758 -21.299 1.00 68.66  ?  4403 EDO   C C1     1 
HETATM 6873 O  O1     . EDO   EA 3 .   ? 104.695 -13.364 -20.919 1.00 69.42  ?  4403 EDO   C O1     1 
HETATM 6874 C  C2     . EDO   EA 3 .   ? 102.377 -13.472 -20.185 1.00 61.05  ?  4403 EDO   C C2     1 
HETATM 6875 O  O2     . EDO   EA 3 .   ? 102.112 -12.068 -20.090 1.00 78.67  ?  4403 EDO   C O2     1 
HETATM 6876 H  H11    . EDO   EA 3 .   ? 103.076 -13.217 -22.200 1.00 82.91  ?  4403 EDO   C H11    1 
HETATM 6877 H  H12    . EDO   EA 3 .   ? 103.363 -14.825 -21.530 1.00 82.91  ?  4403 EDO   C H12    1 
HETATM 6878 H  HO1    . EDO   EA 3 .   ? 105.300 -13.509 -21.660 1.00 83.83  ?  4403 EDO   C HO1    1 
HETATM 6879 H  H21    . EDO   EA 3 .   ? 102.778 -13.832 -19.235 1.00 73.78  ?  4403 EDO   C H21    1 
HETATM 6880 H  H22    . EDO   EA 3 .   ? 101.445 -14.007 -20.381 1.00 73.78  ?  4403 EDO   C H22    1 
HETATM 6881 H  HO2    . EDO   EA 3 .   ? 101.510 -11.903 -19.352 1.00 94.92  ?  4403 EDO   C HO2    1 
HETATM 6882 CL CL     . CL    FA 7 .   ? 102.216 -9.913  -3.545  1.00 68.69  ?  4404 CL    C CL     1 
HETATM 6883 C  C1     . EDO   GA 3 .   ? 104.028 -21.383 -5.652  1.00 66.52  ?  4405 EDO   C C1     1 
HETATM 6884 O  O1     . EDO   GA 3 .   ? 103.732 -22.283 -6.720  1.00 71.20  ?  4405 EDO   C O1     1 
HETATM 6885 C  C2     . EDO   GA 3 .   ? 102.760 -20.655 -5.251  1.00 55.66  ?  4405 EDO   C C2     1 
HETATM 6886 O  O2     . EDO   GA 3 .   ? 102.753 -19.454 -6.010  1.00 58.36  ?  4405 EDO   C O2     1 
HETATM 6887 H  H11    . EDO   GA 3 .   ? 104.427 -21.936 -4.799  1.00 80.34  ?  4405 EDO   C H11    1 
HETATM 6888 H  H12    . EDO   GA 3 .   ? 104.786 -20.664 -5.970  1.00 80.34  ?  4405 EDO   C H12    1 
HETATM 6889 H  HO1    . EDO   GA 3 .   ? 104.539 -22.745 -6.986  1.00 85.97  ?  4405 EDO   C HO1    1 
HETATM 6890 H  H21    . EDO   GA 3 .   ? 101.878 -21.260 -5.471  1.00 67.31  ?  4405 EDO   C H21    1 
HETATM 6891 H  H22    . EDO   GA 3 .   ? 102.760 -20.438 -4.180  1.00 67.31  ?  4405 EDO   C H22    1 
HETATM 6892 H  HO2    . EDO   GA 3 .   ? 102.496 -18.715 -5.442  1.00 70.55  ?  4405 EDO   C HO2    1 
HETATM 6893 O  O      . HOH   HA 9 .   ? 85.445  -24.738 -18.367 1.00 46.24  ?  7301 HOH   B O      1 
HETATM 6894 O  O      . HOH   HA 9 .   ? 80.072  -9.728  -1.462  1.00 49.87  ?  7302 HOH   B O      1 
HETATM 6895 O  O      . HOH   HA 9 .   ? 94.734  -39.554 -1.802  1.00 51.50  ?  7303 HOH   B O      1 
HETATM 6896 O  O      . HOH   HA 9 .   ? 66.287  -41.926 -7.124  1.00 59.45  ?  7304 HOH   B O      1 
HETATM 6897 O  O      . HOH   HA 9 .   ? 85.943  -22.409 2.166   1.00 42.26  ?  7305 HOH   B O      1 
HETATM 6898 O  O      . HOH   HA 9 .   ? 83.524  -5.968  -15.575 1.00 56.38  ?  7306 HOH   B O      1 
HETATM 6899 O  O      . HOH   HA 9 .   ? 60.590  -25.667 14.960  1.00 63.27  ?  7307 HOH   B O      1 
HETATM 6900 O  O      . HOH   HA 9 .   ? 63.352  -29.730 -2.585  1.00 50.25  ?  7308 HOH   B O      1 
HETATM 6901 O  O      . HOH   HA 9 .   ? 70.601  -36.536 -0.134  1.00 44.72  ?  7309 HOH   B O      1 
HETATM 6902 O  O      . HOH   HA 9 .   ? 65.112  -7.464  -6.813  1.00 68.01  ?  7310 HOH   B O      1 
HETATM 6903 O  O      . HOH   HA 9 .   ? 65.675  -33.893 -11.359 1.00 51.30  ?  7311 HOH   B O      1 
HETATM 6904 O  O      . HOH   HA 9 .   ? 69.564  -41.163 -5.699  1.00 56.08  ?  7312 HOH   B O      1 
HETATM 6905 O  O      . HOH   HA 9 .   ? 60.477  -19.373 -3.524  1.00 46.97  ?  7313 HOH   B O      1 
HETATM 6906 O  O      . HOH   HA 9 .   ? 87.421  -38.374 -2.513  1.00 39.34  ?  7314 HOH   B O      1 
HETATM 6907 O  O      . HOH   HA 9 .   ? 88.338  -5.054  3.014   1.00 58.14  ?  7315 HOH   B O      1 
HETATM 6908 O  O      . HOH   HA 9 .   ? 74.851  -40.408 1.427   1.00 49.25  ?  7316 HOH   B O      1 
HETATM 6909 O  O      . HOH   HA 9 .   ? 73.522  -38.934 -10.350 1.00 62.60  ?  7317 HOH   B O      1 
HETATM 6910 O  O      . HOH   HA 9 .   ? 74.832  -27.199 17.768  1.00 37.48  ?  7318 HOH   B O      1 
HETATM 6911 O  O      . HOH   HA 9 .   ? 72.089  -44.245 2.548   1.00 57.16  ?  7319 HOH   B O      1 
HETATM 6912 O  O      . HOH   HA 9 .   ? 91.118  -39.138 10.075  1.00 60.83  ?  7320 HOH   B O      1 
HETATM 6913 O  O      . HOH   HA 9 .   ? 82.877  -30.398 5.817   1.00 48.08  ?  7321 HOH   B O      1 
HETATM 6914 O  O      . HOH   HA 9 .   ? 79.119  -17.208 9.230   1.00 44.17  ?  7322 HOH   B O      1 
HETATM 6915 O  O      . HOH   HA 9 .   ? 87.799  -26.573 9.018   1.00 59.66  ?  7323 HOH   B O      1 
HETATM 6916 O  O      . HOH   HA 9 .   ? 87.194  -18.223 -4.554  1.00 39.48  ?  7324 HOH   B O      1 
HETATM 6917 O  O      . HOH   HA 9 .   ? 75.202  -31.864 -13.839 1.00 49.57  ?  7325 HOH   B O      1 
HETATM 6918 O  O      . HOH   HA 9 .   ? 63.554  -15.720 -8.767  1.00 53.73  ?  7326 HOH   B O      1 
HETATM 6919 O  O      . HOH   HA 9 .   ? 83.134  -18.718 -16.262 1.00 39.80  ?  7327 HOH   B O      1 
HETATM 6920 O  O      . HOH   HA 9 .   ? 90.446  -16.725 -9.564  1.00 36.92  ?  7328 HOH   B O      1 
HETATM 6921 O  O      . HOH   HA 9 .   ? 68.718  -23.089 18.223  1.00 60.31  ?  7329 HOH   B O      1 
HETATM 6922 O  O      . HOH   HA 9 .   ? 64.477  -29.424 16.462  1.00 53.46  ?  7330 HOH   B O      1 
HETATM 6923 O  O      . HOH   HA 9 .   ? 69.206  -29.735 -20.070 1.00 51.51  ?  7331 HOH   B O      1 
HETATM 6924 O  O      . HOH   HA 9 .   ? 82.883  -29.812 3.056   1.00 37.84  ?  7332 HOH   B O      1 
HETATM 6925 O  O      . HOH   HA 9 .   ? 87.123  -9.932  -11.862 1.00 47.30  ?  7333 HOH   B O      1 
HETATM 6926 O  O      . HOH   HA 9 .   ? 72.854  -34.972 17.528  1.00 55.32  ?  7334 HOH   B O      1 
HETATM 6927 O  O      . HOH   HA 9 .   ? 62.095  -16.722 -13.753 1.00 54.97  ?  7335 HOH   B O      1 
HETATM 6928 O  O      . HOH   HA 9 .   ? 86.338  -5.209  -8.386  1.00 61.45  ?  7336 HOH   B O      1 
HETATM 6929 O  O      . HOH   HA 9 .   ? 82.477  -27.403 -18.738 1.00 48.22  ?  7337 HOH   B O      1 
HETATM 6930 O  O      . HOH   HA 9 .   ? 65.601  -27.137 -15.072 1.00 52.68  ?  7338 HOH   B O      1 
HETATM 6931 O  O      . HOH   HA 9 .   ? 71.007  -32.318 16.374  1.00 41.20  ?  7339 HOH   B O      1 
HETATM 6932 O  O      . HOH   HA 9 .   ? 81.173  -28.126 18.189  1.00 56.91  ?  7340 HOH   B O      1 
HETATM 6933 O  O      . HOH   HA 9 .   ? 70.073  -25.893 -12.367 1.00 37.82  ?  7341 HOH   B O      1 
HETATM 6934 O  O      . HOH   HA 9 .   ? 70.519  -22.088 -23.766 1.00 46.65  ?  7342 HOH   B O      1 
HETATM 6935 O  O      . HOH   HA 9 .   ? 78.511  -20.179 6.238   1.00 35.86  ?  7343 HOH   B O      1 
HETATM 6936 O  O      . HOH   HA 9 .   ? 89.595  -32.370 -16.911 1.00 44.20  ?  7344 HOH   B O      1 
HETATM 6937 O  O      . HOH   HA 9 .   ? 81.421  -26.594 14.382  1.00 52.48  ?  7345 HOH   B O      1 
HETATM 6938 O  O      . HOH   HA 9 .   ? 75.960  -42.096 3.386   1.00 56.93  ?  7346 HOH   B O      1 
HETATM 6939 O  O      . HOH   HA 9 .   ? 59.665  -25.222 2.577   1.00 42.83  ?  7347 HOH   B O      1 
HETATM 6940 O  O      . HOH   HA 9 .   ? 66.424  -28.514 -22.551 1.00 52.92  ?  7348 HOH   B O      1 
HETATM 6941 O  O      . HOH   HA 9 .   ? 100.417 -32.131 -7.326  1.00 40.38  ?  7349 HOH   B O      1 
HETATM 6942 O  O      . HOH   HA 9 .   ? 79.043  -37.272 17.934  1.00 50.36  ?  7350 HOH   B O      1 
HETATM 6943 O  O      . HOH   HA 9 .   ? 91.698  -31.887 5.650   1.00 54.21  ?  7351 HOH   B O      1 
HETATM 6944 O  O      . HOH   HA 9 .   ? 67.110  -16.510 11.047  1.00 53.49  ?  7352 HOH   B O      1 
HETATM 6945 O  O      . HOH   HA 9 .   ? 59.023  -37.270 8.315   1.00 49.05  ?  7353 HOH   B O      1 
HETATM 6946 O  O      . HOH   HA 9 .   ? 70.903  -22.922 6.507   1.00 46.75  ?  7354 HOH   B O      1 
HETATM 6947 O  O      . HOH   HA 9 .   ? 77.407  -10.871 7.610   1.00 55.39  ?  7355 HOH   B O      1 
HETATM 6948 O  O      . HOH   HA 9 .   ? 92.452  -15.618 -8.240  1.00 41.42  ?  7356 HOH   B O      1 
HETATM 6949 O  O      . HOH   HA 9 .   ? 86.169  -11.620 -19.103 1.00 59.30  ?  7357 HOH   B O      1 
HETATM 6950 O  O      . HOH   HA 9 .   ? 77.663  -19.262 2.834   1.00 37.10  ?  7358 HOH   B O      1 
HETATM 6951 O  O      . HOH   HA 9 .   ? 72.334  -42.468 13.140  1.00 49.67  ?  7359 HOH   B O      1 
HETATM 6952 O  O      . HOH   HA 9 .   ? 101.322 -24.258 -5.018  1.00 59.01  ?  7360 HOH   B O      1 
HETATM 6953 O  O      . HOH   HA 9 .   ? 58.236  -22.517 2.319   1.00 51.85  ?  7361 HOH   B O      1 
HETATM 6954 O  O      . HOH   HA 9 .   ? 71.955  -24.581 -13.075 1.00 39.45  ?  7362 HOH   B O      1 
HETATM 6955 O  O      . HOH   HA 9 .   ? 80.388  -12.170 -0.924  1.00 43.87  ?  7363 HOH   B O      1 
HETATM 6956 O  O      . HOH   HA 9 .   ? 83.875  -20.876 -17.762 1.00 38.66  ?  7364 HOH   B O      1 
HETATM 6957 O  O      . HOH   HA 9 .   ? 79.305  1.017   -7.945  1.00 41.41  ?  7365 HOH   B O      1 
HETATM 6958 O  O      . HOH   HA 9 .   ? 75.799  -9.588  -20.742 1.00 57.11  ?  7366 HOH   B O      1 
HETATM 6959 O  O      . HOH   HA 9 .   ? 84.781  -40.713 2.822   1.00 44.53  ?  7367 HOH   B O      1 
HETATM 6960 O  O      . HOH   HA 9 .   ? 59.717  -17.719 6.573   1.00 59.15  ?  7368 HOH   B O      1 
HETATM 6961 O  O      . HOH   HA 9 .   ? 80.943  -22.103 12.684  1.00 50.42  ?  7369 HOH   B O      1 
HETATM 6962 O  O      . HOH   HA 9 .   ? 83.312  -36.832 9.869   1.00 43.80  ?  7370 HOH   B O      1 
HETATM 6963 O  O      . HOH   HA 9 .   ? 83.820  -25.245 -22.680 1.00 52.18  ?  7371 HOH   B O      1 
HETATM 6964 O  O      . HOH   HA 9 .   ? 80.374  -36.612 10.171  1.00 41.28  ?  7372 HOH   B O      1 
HETATM 6965 O  O      . HOH   HA 9 .   ? 66.133  -5.539  -9.492  1.00 60.70  ?  7373 HOH   B O      1 
HETATM 6966 O  O      . HOH   HA 9 .   ? 60.654  -16.747 -6.432  1.00 54.65  ?  7374 HOH   B O      1 
HETATM 6967 O  O      . HOH   HA 9 .   ? 76.304  -40.863 5.763   1.00 51.62  ?  7375 HOH   B O      1 
HETATM 6968 O  O      . HOH   HA 9 .   ? 73.363  -18.188 18.043  1.00 57.09  ?  7376 HOH   B O      1 
HETATM 6969 O  O      . HOH   HA 9 .   ? 81.656  -36.965 -9.929  1.00 55.35  ?  7377 HOH   B O      1 
HETATM 6970 O  O      . HOH   HA 9 .   ? 84.624  -45.113 3.878   1.00 63.68  ?  7378 HOH   B O      1 
HETATM 6971 O  O      . HOH   HA 9 .   ? 91.413  -42.138 2.538   1.00 57.69  ?  7379 HOH   B O      1 
HETATM 6972 O  O      . HOH   HA 9 .   ? 83.805  -37.817 12.558  1.00 58.94  ?  7380 HOH   B O      1 
HETATM 6973 O  O      . HOH   HA 9 .   ? 90.502  -9.337  -9.976  1.00 53.34  ?  7381 HOH   B O      1 
HETATM 6974 O  O      . HOH   HA 9 .   ? 74.674  -8.718  4.795   1.00 50.51  ?  7382 HOH   B O      1 
HETATM 6975 O  O      . HOH   HA 9 .   ? 62.421  -20.001 9.279   1.00 54.41  ?  7383 HOH   B O      1 
HETATM 6976 O  O      . HOH   HA 9 .   ? 61.847  -22.799 9.245   1.00 47.70  ?  7384 HOH   B O      1 
HETATM 6977 O  O      . HOH   HA 9 .   ? 64.704  -12.187 -22.834 1.00 58.51  ?  7385 HOH   B O      1 
HETATM 6978 O  O      . HOH   HA 9 .   ? 71.374  -1.575  -17.790 1.00 62.83  ?  7386 HOH   B O      1 
HETATM 6979 O  O      . HOH   HA 9 .   ? 58.507  -33.650 -18.659 1.00 62.00  ?  7387 HOH   B O      1 
HETATM 6980 O  O      . HOH   HA 9 .   ? 87.280  -28.393 -17.485 1.00 52.15  ?  7388 HOH   B O      1 
HETATM 6981 O  O      . HOH   HA 9 .   ? 65.348  -9.648  -12.486 1.00 58.52  ?  7389 HOH   B O      1 
HETATM 6982 O  O      . HOH   HA 9 .   ? 58.676  -31.236 -8.676  1.00 57.17  ?  7390 HOH   B O      1 
HETATM 6983 O  O      . HOH   HA 9 .   ? 82.742  -35.303 -12.031 1.00 48.97  ?  7391 HOH   B O      1 
HETATM 6984 O  O      . HOH   HA 9 .   ? 80.665  -34.624 -16.121 1.00 56.04  ?  7392 HOH   B O      1 
HETATM 6985 O  O      . HOH   HA 9 .   ? 63.564  -39.282 -4.043  1.00 50.31  ?  7393 HOH   B O      1 
HETATM 6986 O  O      . HOH   HA 9 .   ? 80.986  -38.124 13.579  1.00 57.03  ?  7394 HOH   B O      1 
HETATM 6987 O  O      . HOH   HA 9 .   ? 90.990  -27.761 -9.798  1.00 36.14  ?  7395 HOH   B O      1 
HETATM 6988 O  O      . HOH   HA 9 .   ? 86.570  -24.940 -24.163 1.00 56.64  ?  7396 HOH   B O      1 
HETATM 6989 O  O      . HOH   HA 9 .   ? 91.444  -41.121 6.113   1.00 56.50  ?  7397 HOH   B O      1 
HETATM 6990 O  O      . HOH   HA 9 .   ? 83.409  -3.410  -6.486  1.00 50.54  ?  7398 HOH   B O      1 
HETATM 6991 O  O      . HOH   HA 9 .   ? 71.353  -9.373  10.241  1.00 57.43  ?  7399 HOH   B O      1 
HETATM 6992 O  O      . HOH   HA 9 .   ? 76.353  -19.761 17.593  1.00 55.45  ?  7400 HOH   B O      1 
HETATM 6993 O  O      . HOH   HA 9 .   ? 86.763  -23.152 -19.179 1.00 49.42  ?  7401 HOH   B O      1 
HETATM 6994 O  O      . HOH   HA 9 .   ? 68.441  -42.547 3.688   1.00 47.32  ?  7402 HOH   B O      1 
HETATM 6995 O  O      . HOH   HA 9 .   ? 53.102  -24.451 -3.760  1.00 59.53  ?  7403 HOH   B O      1 
HETATM 6996 O  O      . HOH   HA 9 .   ? 79.273  -41.835 6.411   1.00 58.05  ?  7404 HOH   B O      1 
HETATM 6997 O  O      . HOH   HA 9 .   ? 83.376  8.375   0.821   1.00 50.44  ?  7405 HOH   B O      1 
HETATM 6998 O  O      . HOH   HA 9 .   ? 60.682  -33.169 -7.445  1.00 51.47  ?  7406 HOH   B O      1 
HETATM 6999 O  O      . HOH   HA 9 .   ? 50.464  -21.018 -12.822 1.00 69.89  ?  7407 HOH   B O      1 
HETATM 7000 O  O      . HOH   HA 9 .   ? 80.319  1.645   0.850   1.00 55.94  ?  7408 HOH   B O      1 
HETATM 7001 O  O      . HOH   HA 9 .   ? 72.401  -13.410 13.447  1.00 51.15  ?  7409 HOH   B O      1 
HETATM 7002 O  O      . HOH   HA 9 .   ? 101.803 -29.471 -0.452  1.00 54.75  ?  7410 HOH   B O      1 
HETATM 7003 O  O      . HOH   HA 9 .   ? 93.067  -37.184 -13.649 1.00 49.19  ?  7411 HOH   B O      1 
HETATM 7004 O  O      . HOH   HA 9 .   ? 95.644  -9.638  -3.910  1.00 55.21  ?  7412 HOH   B O      1 
HETATM 7005 O  O      . HOH   HA 9 .   ? 67.095  -19.912 16.557  1.00 58.39  ?  7413 HOH   B O      1 
HETATM 7006 O  O      . HOH   HA 9 .   ? 88.448  -24.778 5.087   1.00 44.07  ?  7414 HOH   B O      1 
HETATM 7007 O  O      . HOH   HA 9 .   ? 64.109  -15.502 -22.589 1.00 54.89  ?  7415 HOH   B O      1 
HETATM 7008 O  O      . HOH   HA 9 .   ? 65.686  -17.698 15.288  1.00 59.07  ?  7416 HOH   B O      1 
HETATM 7009 O  O      . HOH   HA 9 .   ? 69.656  -8.175  3.039   1.00 57.34  ?  7417 HOH   B O      1 
HETATM 7010 O  O      . HOH   HA 9 .   ? 63.745  -13.174 -15.560 1.00 58.41  ?  7418 HOH   B O      1 
HETATM 7011 O  O      . HOH   HA 9 .   ? 89.162  -39.650 8.712   1.00 55.14  ?  7419 HOH   B O      1 
HETATM 7012 O  O      . HOH   HA 9 .   ? 69.651  -40.308 0.076   1.00 47.77  ?  7420 HOH   B O      1 
HETATM 7013 O  O      . HOH   HA 9 .   ? 74.602  -12.128 -21.991 1.00 53.88  ?  7421 HOH   B O      1 
HETATM 7014 O  O      . HOH   HA 9 .   ? 86.486  -37.687 -13.354 1.00 50.40  ?  7422 HOH   B O      1 
HETATM 7015 O  O      . HOH   HA 9 .   ? 55.794  -31.176 2.749   1.00 55.99  ?  7423 HOH   B O      1 
HETATM 7016 O  O      . HOH   HA 9 .   ? 89.003  -6.970  -7.871  1.00 57.11  ?  7424 HOH   B O      1 
HETATM 7017 O  O      . HOH   HA 9 .   ? 76.623  -39.542 -0.926  1.00 42.86  ?  7425 HOH   B O      1 
HETATM 7018 O  O      . HOH   HA 9 .   ? 66.250  -27.958 17.855  1.00 51.61  ?  7426 HOH   B O      1 
HETATM 7019 O  O      . HOH   HA 9 .   ? 91.265  -39.087 15.000  1.00 62.43  ?  7427 HOH   B O      1 
HETATM 7020 O  O      . HOH   HA 9 .   ? 60.226  -12.870 -11.406 1.00 64.19  ?  7428 HOH   B O      1 
HETATM 7021 O  O      . HOH   HA 9 .   ? 62.107  -11.189 -20.640 1.00 61.05  ?  7429 HOH   B O      1 
HETATM 7022 O  O      . HOH   HA 9 .   ? 66.680  -14.852 7.834   1.00 55.63  ?  7430 HOH   B O      1 
HETATM 7023 O  O      . HOH   HA 9 .   ? 83.361  -42.176 4.505   1.00 55.68  ?  7431 HOH   B O      1 
HETATM 7024 O  O      . HOH   HA 9 .   ? 79.328  -41.122 -1.218  1.00 57.75  ?  7432 HOH   B O      1 
HETATM 7025 O  O      . HOH   HA 9 .   ? 60.866  -17.065 -24.492 1.00 54.05  ?  7433 HOH   B O      1 
HETATM 7026 O  O      . HOH   HA 9 .   ? 95.681  -25.494 2.284   1.00 49.32  ?  7434 HOH   B O      1 
HETATM 7027 O  O      . HOH   HA 9 .   ? 76.372  8.352   6.004   1.00 54.09  ?  7435 HOH   B O      1 
HETATM 7028 O  O      . HOH   HA 9 .   ? 82.494  -34.386 -18.729 1.00 56.82  ?  7436 HOH   B O      1 
HETATM 7029 O  O      . HOH   HA 9 .   ? 89.545  -26.886 6.552   1.00 53.29  ?  7437 HOH   B O      1 
HETATM 7030 O  O      . HOH   HA 9 .   ? 99.435  -37.561 -2.629  1.00 49.54  ?  7438 HOH   B O      1 
HETATM 7031 O  O      . HOH   HA 9 .   ? 70.190  -31.681 -16.785 1.00 56.62  ?  7439 HOH   B O      1 
HETATM 7032 O  O      . HOH   HA 9 .   ? 98.307  -23.633 -4.822  1.00 56.45  ?  7440 HOH   B O      1 
HETATM 7033 O  O      . HOH   HA 9 .   ? 79.679  12.773  5.702   1.00 60.88  ?  7441 HOH   B O      1 
HETATM 7034 O  O      . HOH   HA 9 .   ? 67.053  -15.868 14.581  1.00 62.04  ?  7442 HOH   B O      1 
HETATM 7035 O  O      . HOH   HA 9 .   ? 94.303  -30.678 4.094   1.00 54.01  ?  7443 HOH   B O      1 
HETATM 7036 O  O      . HOH   HA 9 .   ? 80.192  -2.569  1.796   1.00 45.24  ?  7444 HOH   B O      1 
HETATM 7037 O  O      . HOH   HA 9 .   ? 67.106  -21.470 -25.484 1.00 49.94  ?  7445 HOH   B O      1 
HETATM 7038 O  O      . HOH   HA 9 .   ? 83.188  -5.349  -11.643 1.00 61.78  ?  7446 HOH   B O      1 
HETATM 7039 O  O      . HOH   HA 9 .   ? 86.173  -6.962  -12.342 1.00 50.15  ?  7447 HOH   B O      1 
HETATM 7040 O  O      . HOH   HA 9 .   ? 76.626  -34.460 20.796  1.00 50.29  ?  7448 HOH   B O      1 
HETATM 7041 O  O      . HOH   HA 9 .   ? 65.098  -12.509 3.194   1.00 55.83  ?  7449 HOH   B O      1 
HETATM 7042 O  O      . HOH   HA 9 .   ? 60.799  -14.789 -17.307 1.00 56.22  ?  7450 HOH   B O      1 
HETATM 7043 O  O      . HOH   HA 9 .   ? 84.102  -39.473 -12.586 1.00 65.89  ?  7451 HOH   B O      1 
HETATM 7044 O  O      . HOH   HA 9 .   ? 88.084  -12.437 -16.526 1.00 48.98  ?  7452 HOH   B O      1 
HETATM 7045 O  O      . HOH   HA 9 .   ? 81.558  -23.842 -24.319 1.00 66.30  ?  7453 HOH   B O      1 
HETATM 7046 O  O      . HOH   HA 9 .   ? 57.199  -13.043 -20.450 1.00 70.09  ?  7454 HOH   B O      1 
HETATM 7047 O  O      . HOH   HA 9 .   ? 72.826  -28.470 -27.811 1.00 63.07  ?  7455 HOH   B O      1 
HETATM 7048 O  O      . HOH   HA 9 .   ? 97.978  -31.826 2.915   1.00 55.58  ?  7456 HOH   B O      1 
HETATM 7049 O  O      . HOH   HA 9 .   ? 58.203  -16.679 -6.676  1.00 65.28  ?  7457 HOH   B O      1 
HETATM 7050 O  O      . HOH   HA 9 .   ? 90.248  -23.071 3.826   1.00 59.34  ?  7458 HOH   B O      1 
HETATM 7051 O  O      . HOH   HA 9 .   ? 85.500  -19.446 -19.555 1.00 46.19  ?  7459 HOH   B O      1 
HETATM 7052 O  O      . HOH   HA 9 .   ? 67.669  -7.824  -17.789 1.00 63.87  ?  7460 HOH   B O      1 
HETATM 7053 O  O      . HOH   HA 9 .   ? 71.472  -14.799 15.463  1.00 59.34  ?  7461 HOH   B O      1 
HETATM 7054 O  O      . HOH   HA 9 .   ? 89.277  -29.349 -16.323 1.00 40.15  ?  7462 HOH   B O      1 
HETATM 7055 O  O      . HOH   HA 9 .   ? 95.840  -35.287 10.603  1.00 62.60  ?  7463 HOH   B O      1 
HETATM 7056 O  O      . HOH   HA 9 .   ? 57.080  -18.203 -3.152  1.00 62.55  ?  7464 HOH   B O      1 
HETATM 7057 O  O      . HOH   HA 9 .   ? 86.482  -40.305 11.406  1.00 61.17  ?  7465 HOH   B O      1 
HETATM 7058 O  O      . HOH   HA 9 .   ? 66.215  -37.753 -9.190  1.00 59.67  ?  7466 HOH   B O      1 
HETATM 7059 O  O      . HOH   HA 9 .   ? 80.609  -24.139 13.583  1.00 47.02  ?  7467 HOH   B O      1 
HETATM 7060 O  O      . HOH   HA 9 .   ? 88.607  -29.700 12.093  1.00 57.13  ?  7468 HOH   B O      1 
HETATM 7061 O  O      . HOH   HA 9 .   ? 59.693  -35.816 6.228   1.00 56.99  ?  7469 HOH   B O      1 
HETATM 7062 O  O      . HOH   HA 9 .   ? 73.403  -17.165 21.983  1.00 67.39  ?  7470 HOH   B O      1 
HETATM 7063 O  O      . HOH   HA 9 .   ? 71.453  -38.606 -1.592  1.00 46.53  ?  7471 HOH   B O      1 
HETATM 7064 O  O      . HOH   HA 9 .   ? 93.152  -22.690 0.753   1.00 52.90  ?  7472 HOH   B O      1 
HETATM 7065 O  O      . HOH   HA 9 .   ? 78.625  -39.029 -4.305  1.00 48.84  ?  7473 HOH   B O      1 
HETATM 7066 O  O      . HOH   HA 9 .   ? 89.513  -3.974  0.859   1.00 61.46  ?  7474 HOH   B O      1 
HETATM 7067 O  O      . HOH   HA 9 .   ? 70.421  -0.687  -7.290  1.00 55.63  ?  7475 HOH   B O      1 
HETATM 7068 O  O      . HOH   HA 9 .   ? 56.513  -20.705 -10.122 1.00 54.75  ?  7476 HOH   B O      1 
HETATM 7069 O  O      . HOH   HA 9 .   ? 72.315  -24.820 21.103  1.00 46.52  ?  7477 HOH   B O      1 
HETATM 7070 O  O      . HOH   HA 9 .   ? 70.358  1.968   -1.754  1.00 67.60  ?  7478 HOH   B O      1 
HETATM 7071 O  O      . HOH   HA 9 .   ? 78.245  -33.015 -16.035 1.00 55.69  ?  7479 HOH   B O      1 
HETATM 7072 O  O      . HOH   HA 9 .   ? 55.951  -32.944 -0.727  1.00 56.78  ?  7480 HOH   B O      1 
HETATM 7073 O  O      . HOH   HA 9 .   ? 78.466  -1.940  3.490   1.00 52.49  ?  7481 HOH   B O      1 
HETATM 7074 O  O      . HOH   HA 9 .   ? 99.222  -29.603 0.119   1.00 59.86  ?  7482 HOH   B O      1 
HETATM 7075 O  O      . HOH   HA 9 .   ? 85.756  -35.314 -12.041 1.00 47.25  ?  7483 HOH   B O      1 
HETATM 7076 O  O      . HOH   HA 9 .   ? 74.108  -37.961 19.080  1.00 56.22  ?  7484 HOH   B O      1 
HETATM 7077 O  O      . HOH   HA 9 .   ? 65.301  -17.600 9.727   1.00 44.70  ?  7485 HOH   B O      1 
HETATM 7078 O  O      . HOH   HA 9 .   ? 61.727  -31.266 17.286  1.00 59.36  ?  7486 HOH   B O      1 
HETATM 7079 O  O      . HOH   HA 9 .   ? 72.943  -2.667  2.534   1.00 60.96  ?  7487 HOH   B O      1 
HETATM 7080 O  O      . HOH   HA 9 .   ? 88.987  -46.798 2.325   1.00 62.83  ?  7488 HOH   B O      1 
HETATM 7081 O  O      . HOH   HA 9 .   ? 48.573  -26.645 -13.554 1.00 71.03  ?  7489 HOH   B O      1 
HETATM 7082 O  O      . HOH   HA 9 .   ? 79.018  -43.567 8.374   1.00 58.74  ?  7490 HOH   B O      1 
HETATM 7083 O  O      . HOH   HA 9 .   ? 75.417  -3.457  3.338   1.00 55.80  ?  7491 HOH   B O      1 
HETATM 7084 O  O      . HOH   HA 9 .   ? 74.222  -30.550 23.525  1.00 53.84  ?  7492 HOH   B O      1 
HETATM 7085 O  O      . HOH   HA 9 .   ? 84.359  -43.824 8.589   1.00 56.82  ?  7493 HOH   B O      1 
HETATM 7086 O  O      . HOH   HA 9 .   ? 72.057  -8.205  4.882   1.00 56.48  ?  7494 HOH   B O      1 
HETATM 7087 O  O      . HOH   HA 9 .   ? 67.804  -9.791  9.596   1.00 56.07  ?  7495 HOH   B O      1 
HETATM 7088 O  O      . HOH   HA 9 .   ? 58.874  -23.683 10.660  1.00 58.29  ?  7496 HOH   B O      1 
HETATM 7089 O  O      . HOH   HA 9 .   ? 57.220  -30.135 8.456   1.00 52.87  ?  7497 HOH   B O      1 
HETATM 7090 O  O      . HOH   HA 9 .   ? 63.201  -29.710 -23.434 1.00 66.25  ?  7498 HOH   B O      1 
HETATM 7091 O  O      . HOH   HA 9 .   ? 65.047  -14.617 4.889   1.00 59.99  ?  7499 HOH   B O      1 
HETATM 7092 O  O      . HOH   HA 9 .   ? 62.185  -12.153 -0.908  1.00 57.63  ?  7500 HOH   B O      1 
HETATM 7093 O  O      . HOH   HA 9 .   ? 59.183  -16.817 -3.851  1.00 62.15  ?  7501 HOH   B O      1 
HETATM 7094 O  O      . HOH   HA 9 .   ? 69.696  -33.639 -16.876 1.00 62.60  ?  7502 HOH   B O      1 
HETATM 7095 O  O      . HOH   HA 9 .   ? 90.109  -18.113 3.634   1.00 53.95  ?  7503 HOH   B O      1 
HETATM 7096 O  O      . HOH   HA 9 .   ? 95.573  -10.229 1.001   1.00 58.96  ?  7504 HOH   B O      1 
HETATM 7097 O  O      . HOH   HA 9 .   ? 53.862  -27.396 0.111   1.00 56.68  ?  7505 HOH   B O      1 
HETATM 7098 O  O      . HOH   HA 9 .   ? 69.708  -6.177  -23.596 1.00 61.52  ?  7506 HOH   B O      1 
HETATM 7099 O  O      . HOH   HA 9 .   ? 105.251 -33.024 -0.594  1.00 57.24  ?  7507 HOH   B O      1 
HETATM 7100 O  O      . HOH   HA 9 .   ? 81.452  -37.532 -13.732 1.00 61.21  ?  7508 HOH   B O      1 
HETATM 7101 O  O      . HOH   HA 9 .   ? 93.722  -38.520 8.909   1.00 59.67  ?  7509 HOH   B O      1 
HETATM 7102 O  O      . HOH   HA 9 .   ? 65.725  -31.684 -23.035 1.00 65.81  ?  7510 HOH   B O      1 
HETATM 7103 O  O      . HOH   HA 9 .   ? 64.748  -34.410 -8.739  1.00 56.97  ?  7511 HOH   B O      1 
HETATM 7104 O  O      . HOH   HA 9 .   ? 62.311  -34.273 -9.190  1.00 55.18  ?  7512 HOH   B O      1 
HETATM 7105 O  O      . HOH   HA 9 .   ? 89.543  -41.106 13.082  1.00 62.43  ?  7513 HOH   B O      1 
HETATM 7106 O  O      . HOH   HA 9 .   ? 87.586  -42.218 9.167   1.00 60.23  ?  7514 HOH   B O      1 
HETATM 7107 O  O      . HOH   HA 9 .   ? 91.210  -28.438 14.534  1.00 60.88  ?  7515 HOH   B O      1 
HETATM 7108 O  O      . HOH   HA 9 .   ? 55.428  -27.811 -6.856  1.00 55.00  ?  7516 HOH   B O      1 
HETATM 7109 O  O      . HOH   HA 9 .   ? 82.469  -0.778  -5.853  1.00 55.52  ?  7517 HOH   B O      1 
HETATM 7110 O  O      . HOH   HA 9 .   ? 68.137  -30.393 -21.927 1.00 59.49  ?  7518 HOH   B O      1 
HETATM 7111 O  O      . HOH   HA 9 .   ? 75.387  -5.909  -24.504 1.00 61.89  ?  7519 HOH   B O      1 
HETATM 7112 O  O      . HOH   HA 9 .   ? 89.544  -32.499 -19.314 1.00 49.61  ?  7520 HOH   B O      1 
HETATM 7113 O  O      . HOH   HA 9 .   ? 86.556  -48.282 -5.502  1.00 58.14  ?  7521 HOH   B O      1 
HETATM 7114 O  O      . HOH   HA 9 .   ? 65.380  -36.325 -12.636 1.00 59.10  ?  7522 HOH   B O      1 
HETATM 7115 O  O      . HOH   HA 9 .   ? 56.460  -29.888 -7.591  1.00 57.84  ?  7523 HOH   B O      1 
HETATM 7116 O  O      . HOH   HA 9 .   ? 57.360  -25.753 -23.956 1.00 63.74  ?  7524 HOH   B O      1 
HETATM 7117 O  O      . HOH   IA 9 .   ? 115.729 -8.925  -1.926  1.00 60.59  ?  4501 HOH   C O      1 
HETATM 7118 O  O      . HOH   IA 9 .   ? 92.565  -12.219 -20.039 1.00 65.26  ?  4502 HOH   C O      1 
HETATM 7119 O  O      . HOH   IA 9 .   ? 106.360 -11.662 -20.427 1.00 61.16  ?  4503 HOH   C O      1 
HETATM 7120 O  O      . HOH   IA 9 .   ? 112.337 -17.327 -9.331  1.00 57.30  ?  4504 HOH   C O      1 
HETATM 7121 O  O      . HOH   IA 9 .   ? 106.027 -25.800 -31.052 1.00 64.40  ?  4505 HOH   C O      1 
HETATM 7122 O  O      . HOH   IA 9 .   ? 100.059 -25.973 -30.710 1.00 57.66  ?  4506 HOH   C O      1 
HETATM 7123 O  O      . HOH   IA 9 .   ? 99.254  -30.554 -9.377  1.00 43.51  ?  4507 HOH   C O      1 
HETATM 7124 O  O      . HOH   IA 9 .   ? 112.815 -6.554  -16.952 1.00 65.39  ?  4508 HOH   C O      1 
HETATM 7125 O  O      . HOH   IA 9 .   ? 115.056 -15.169 -5.466  1.00 54.84  ?  4509 HOH   C O      1 
HETATM 7126 O  O      . HOH   IA 9 .   ? 105.975 -32.773 -14.085 1.00 51.51  ?  4510 HOH   C O      1 
HETATM 7127 O  O      . HOH   IA 9 .   ? 109.981 -17.970 -23.356 1.00 53.18  ?  4511 HOH   C O      1 
HETATM 7128 O  O      . HOH   IA 9 .   ? 94.178  -16.943 -10.392 1.00 41.51  ?  4512 HOH   C O      1 
HETATM 7129 O  O      . HOH   IA 9 .   ? 98.507  -28.609 -11.985 1.00 38.13  ?  4513 HOH   C O      1 
HETATM 7130 O  O      . HOH   IA 9 .   ? 102.714 -31.708 -8.166  1.00 47.59  ?  4514 HOH   C O      1 
HETATM 7131 O  O      . HOH   IA 9 .   ? 91.067  -29.926 -22.807 1.00 55.73  ?  4515 HOH   C O      1 
HETATM 7132 O  O      . HOH   IA 9 .   ? 99.585  -34.275 -23.092 1.00 52.23  ?  4516 HOH   C O      1 
HETATM 7133 O  O      . HOH   IA 9 .   ? 99.016  -20.348 -25.502 1.00 50.99  ?  4517 HOH   C O      1 
HETATM 7134 O  O      . HOH   IA 9 .   ? 95.899  -31.072 -17.630 1.00 42.82  ?  4518 HOH   C O      1 
HETATM 7135 O  O      . HOH   IA 9 .   ? 114.990 -16.134 -10.799 1.00 61.36  ?  4519 HOH   C O      1 
HETATM 7136 O  O      . HOH   IA 9 .   ? 95.854  -25.251 -5.212  1.00 46.66  ?  4520 HOH   C O      1 
HETATM 7137 O  O      . HOH   IA 9 .   ? 97.108  -30.989 -10.644 1.00 40.94  ?  4521 HOH   C O      1 
HETATM 7138 O  O      . HOH   IA 9 .   ? 94.915  -5.936  -9.356  1.00 51.50  ?  4522 HOH   C O      1 
HETATM 7139 O  O      . HOH   IA 9 .   ? 105.325 -16.506 -8.329  1.00 45.47  ?  4523 HOH   C O      1 
HETATM 7140 O  O      . HOH   IA 9 .   ? 98.130  -10.288 -4.206  1.00 50.36  ?  4524 HOH   C O      1 
HETATM 7141 O  O      . HOH   IA 9 .   ? 95.316  -2.298  -16.055 1.00 56.88  ?  4525 HOH   C O      1 
HETATM 7142 O  O      . HOH   IA 9 .   ? 92.370  -31.861 -16.917 1.00 41.97  ?  4526 HOH   C O      1 
HETATM 7143 O  O      . HOH   IA 9 .   ? 113.558 -18.050 -20.597 1.00 62.95  ?  4527 HOH   C O      1 
HETATM 7144 O  O      . HOH   IA 9 .   ? 109.735 -26.705 -36.962 1.00 76.63  ?  4528 HOH   C O      1 
HETATM 7145 O  O      . HOH   IA 9 .   ? 95.545  -33.057 -24.816 1.00 59.47  ?  4529 HOH   C O      1 
HETATM 7146 O  O      . HOH   IA 9 .   ? 104.460 -24.566 -23.732 1.00 51.94  ?  4530 HOH   C O      1 
HETATM 7147 O  O      . HOH   IA 9 .   ? 99.163  -9.433  -19.369 1.00 62.98  ?  4531 HOH   C O      1 
HETATM 7148 O  O      . HOH   IA 9 .   ? 95.732  -4.788  -11.822 1.00 57.27  ?  4532 HOH   C O      1 
HETATM 7149 O  O      . HOH   IA 9 .   ? 90.697  -28.645 -18.421 1.00 49.41  ?  4533 HOH   C O      1 
HETATM 7150 O  O      . HOH   IA 9 .   ? 89.614  -13.856 -19.783 1.00 56.45  ?  4534 HOH   C O      1 
HETATM 7151 O  O      . HOH   IA 9 .   ? 98.827  -11.688 -2.160  1.00 56.09  ?  4535 HOH   C O      1 
HETATM 7152 O  O      . HOH   IA 9 .   ? 90.739  -18.630 -14.742 1.00 45.91  ?  4536 HOH   C O      1 
HETATM 7153 O  O      . HOH   IA 9 .   ? 93.538  -30.945 -19.500 1.00 48.37  ?  4537 HOH   C O      1 
HETATM 7154 O  O      . HOH   IA 9 .   ? 108.774 -32.820 -15.315 1.00 59.99  ?  4538 HOH   C O      1 
HETATM 7155 O  O      . HOH   IA 9 .   ? 115.531 -12.520 -11.616 1.00 58.13  ?  4539 HOH   C O      1 
HETATM 7156 O  O      . HOH   IA 9 .   ? 106.553 -3.271  -15.417 1.00 55.15  ?  4540 HOH   C O      1 
HETATM 7157 O  O      . HOH   IA 9 .   ? 88.276  -19.264 -19.562 1.00 45.84  ?  4541 HOH   C O      1 
HETATM 7158 O  O      . HOH   IA 9 .   ? 108.227 -18.441 -2.403  1.00 55.94  ?  4542 HOH   C O      1 
HETATM 7159 O  O      . HOH   IA 9 .   ? 95.719  0.352   -7.093  1.00 60.76  ?  4543 HOH   C O      1 
HETATM 7160 O  O      . HOH   IA 9 .   ? 100.855 -13.997 -0.937  1.00 57.81  ?  4544 HOH   C O      1 
HETATM 7161 O  O      . HOH   IA 9 .   ? 103.929 -13.888 -24.338 1.00 62.98  ?  4545 HOH   C O      1 
HETATM 7162 O  O      . HOH   IA 9 .   ? 95.780  -14.663 -23.583 1.00 54.77  ?  4546 HOH   C O      1 
HETATM 7163 O  O      . HOH   IA 9 .   ? 111.145 -25.403 -26.782 1.00 56.84  ?  4547 HOH   C O      1 
HETATM 7164 O  O      . HOH   IA 9 .   ? 109.137 -29.792 -16.016 1.00 52.73  ?  4548 HOH   C O      1 
HETATM 7165 O  O      . HOH   IA 9 .   ? 105.857 -25.442 -34.153 1.00 70.44  ?  4549 HOH   C O      1 
HETATM 7166 O  O      . HOH   IA 9 .   ? 112.117 -20.439 -10.318 1.00 61.29  ?  4550 HOH   C O      1 
HETATM 7167 O  O      . HOH   IA 9 .   ? 106.528 -29.775 -21.881 1.00 57.11  ?  4551 HOH   C O      1 
HETATM 7168 O  O      . HOH   IA 9 .   ? 103.559 -11.600 -14.819 1.00 54.68  ?  4552 HOH   C O      1 
HETATM 7169 O  O      . HOH   IA 9 .   ? 111.187 -16.042 -31.871 1.00 71.06  ?  4553 HOH   C O      1 
HETATM 7170 O  O      . HOH   IA 9 .   ? 111.788 -12.374 0.974   1.00 64.61  ?  4554 HOH   C O      1 
HETATM 7171 O  O      . HOH   IA 9 .   ? 93.549  2.384   -12.862 1.00 58.36  ?  4555 HOH   C O      1 
HETATM 7172 O  O      . HOH   IA 9 .   ? 111.240 -16.692 -12.566 1.00 60.14  ?  4556 HOH   C O      1 
HETATM 7173 O  O      . HOH   IA 9 .   ? 96.523  -21.344 -26.678 1.00 52.38  ?  4557 HOH   C O      1 
HETATM 7174 O  O      . HOH   IA 9 .   ? 101.307 -21.411 -2.713  1.00 60.24  ?  4558 HOH   C O      1 
HETATM 7175 O  O      . HOH   IA 9 .   ? 105.072 -28.376 -30.316 1.00 62.08  ?  4559 HOH   C O      1 
HETATM 7176 O  O      . HOH   IA 9 .   ? 92.898  -22.355 -25.129 1.00 47.80  ?  4560 HOH   C O      1 
HETATM 7177 O  O      . HOH   IA 9 .   ? 103.305 -13.318 -1.963  1.00 49.48  ?  4561 HOH   C O      1 
HETATM 7178 O  O      . HOH   IA 9 .   ? 106.583 -13.087 -1.790  1.00 56.63  ?  4562 HOH   C O      1 
HETATM 7179 O  O      . HOH   IA 9 .   ? 111.676 0.123   -10.145 1.00 64.14  ?  4563 HOH   C O      1 
HETATM 7180 O  O      . HOH   IA 9 .   ? 98.230  -20.669 -31.026 1.00 64.56  ?  4564 HOH   C O      1 
HETATM 7181 O  O      . HOH   IA 9 .   ? 110.643 -19.838 -12.422 1.00 58.15  ?  4565 HOH   C O      1 
HETATM 7182 O  O      . HOH   IA 9 .   ? 92.814  -32.816 -20.928 1.00 55.35  ?  4566 HOH   C O      1 
HETATM 7183 O  O      . HOH   IA 9 .   ? 99.445  -7.227  -20.283 1.00 67.25  ?  4567 HOH   C O      1 
HETATM 7184 O  O      . HOH   IA 9 .   ? 102.134 -2.105  -4.793  1.00 60.41  ?  4568 HOH   C O      1 
HETATM 7185 O  O      . HOH   IA 9 .   ? 102.556 -10.760 -16.935 1.00 56.13  ?  4569 HOH   C O      1 
HETATM 7186 O  O      . HOH   IA 9 .   ? 94.406  -2.125  -9.253  1.00 58.65  ?  4570 HOH   C O      1 
HETATM 7187 O  O      . HOH   IA 9 .   ? 91.223  -8.915  -19.300 1.00 54.71  ?  4571 HOH   C O      1 
HETATM 7188 O  O      . HOH   IA 9 .   ? 118.859 -15.776 -7.335  1.00 61.55  ?  4572 HOH   C O      1 
HETATM 7189 O  O      . HOH   IA 9 .   ? 87.324  -28.612 -20.166 1.00 53.36  ?  4573 HOH   C O      1 
HETATM 7190 O  O      . HOH   IA 9 .   ? 113.828 -19.040 -24.068 1.00 61.39  ?  4574 HOH   C O      1 
HETATM 7191 O  O      . HOH   IA 9 .   ? 106.909 -15.248 -30.562 1.00 60.03  ?  4575 HOH   C O      1 
HETATM 7192 O  O      . HOH   IA 9 .   ? 95.143  -37.453 -23.782 1.00 64.28  ?  4576 HOH   C O      1 
HETATM 7193 O  O      . HOH   IA 9 .   ? 112.222 -27.503 -22.013 1.00 64.29  ?  4577 HOH   C O      1 
HETATM 7194 O  O      . HOH   IA 9 .   ? 100.000 -10.281 -17.610 1.00 61.90  ?  4578 HOH   C O      1 
HETATM 7195 O  O      . HOH   IA 9 .   ? 96.186  0.827   -18.095 1.00 62.02  ?  4579 HOH   C O      1 
HETATM 7196 O  O      . HOH   IA 9 .   ? 110.836 -30.156 -10.652 1.00 62.85  ?  4580 HOH   C O      1 
HETATM 7197 O  O      . HOH   IA 9 .   ? 92.396  -6.425  -16.181 1.00 63.39  ?  4581 HOH   C O      1 
HETATM 7198 O  O      . HOH   IA 9 .   ? 112.129 -18.716 -15.436 1.00 59.27  ?  4582 HOH   C O      1 
HETATM 7199 O  O      . HOH   IA 9 .   ? 107.012 -27.501 -20.085 1.00 53.99  ?  4583 HOH   C O      1 
HETATM 7200 O  O      . HOH   IA 9 .   ? 98.494  -17.314 -25.490 1.00 57.80  ?  4584 HOH   C O      1 
HETATM 7201 O  O      . HOH   IA 9 .   ? 97.782  -33.107 -26.680 1.00 55.88  ?  4585 HOH   C O      1 
HETATM 7202 O  O      . HOH   IA 9 .   ? 98.583  -7.120  -1.985  1.00 59.20  ?  4586 HOH   C O      1 
HETATM 7203 O  O      . HOH   IA 9 .   ? 89.423  -26.095 -24.439 1.00 53.18  ?  4587 HOH   C O      1 
HETATM 7204 O  O      . HOH   IA 9 .   ? 115.336 -11.878 -15.733 1.00 62.59  ?  4588 HOH   C O      1 
HETATM 7205 O  O      . HOH   IA 9 .   ? 89.794  -30.229 -20.376 1.00 54.63  ?  4589 HOH   C O      1 
HETATM 7206 O  O      . HOH   IA 9 .   ? 92.939  -7.761  -12.124 1.00 60.03  ?  4590 HOH   C O      1 
# 
